KEGG   Pongo abelii (Sumatran orangutan): 100453768
Entry
100453768         CDS       T01416                                 
Symbol
ITGB4
Name
(RefSeq) integrin beta-4 isoform X1
  KO
K06525  integrin beta 4
Organism
pon  Pongo abelii (Sumatran orangutan)
Pathway
pon04151  PI3K-Akt signaling pathway
pon04510  Focal adhesion
pon04512  ECM-receptor interaction
pon04810  Regulation of actin cytoskeleton
pon04820  Cytoskeleton in muscle cells
pon05165  Human papillomavirus infection
pon05410  Hypertrophic cardiomyopathy
pon05412  Arrhythmogenic right ventricular cardiomyopathy
pon05414  Dilated cardiomyopathy
Brite
KEGG Orthology (KO) [BR:pon00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04151 PI3K-Akt signaling pathway
    100453768 (ITGB4)
  09133 Signaling molecules and interaction
   04512 ECM-receptor interaction
    100453768 (ITGB4)
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    100453768 (ITGB4)
  09142 Cell motility
   04820 Cytoskeleton in muscle cells
    100453768 (ITGB4)
   04810 Regulation of actin cytoskeleton
    100453768 (ITGB4)
 09160 Human Diseases
  09172 Infectious disease: viral
   05165 Human papillomavirus infection
    100453768 (ITGB4)
  09166 Cardiovascular disease
   05410 Hypertrophic cardiomyopathy
    100453768 (ITGB4)
   05412 Arrhythmogenic right ventricular cardiomyopathy
    100453768 (ITGB4)
   05414 Dilated cardiomyopathy
    100453768 (ITGB4)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04147 Exosome [BR:pon04147]
    100453768 (ITGB4)
   04515 Cell adhesion molecules [BR:pon04515]
    100453768 (ITGB4)
   04090 CD molecules [BR:pon04090]
    100453768 (ITGB4)
Exosome [BR:pon04147]
 Exosomal proteins
  Exosomal proteins of colorectal cancer cells
   100453768 (ITGB4)
  Exosomal proteins of bladder cancer cells
   100453768 (ITGB4)
Cell adhesion molecules [BR:pon04515]
 Integrins
  Integrin beta subunits
   100453768 (ITGB4)
CD molecules [BR:pon04090]
 Proteins
  100453768 (ITGB4)
SSDB
Motif
Pfam: Integrin_beta fn3 Calx-beta Integrin_B_tail Pur_ac_phosph_N I-EGF_1 PSI_integrin EGF_2 SEA
Other DBs
NCBI-GeneID: 100453768
NCBI-ProteinID: XP_024091018
Ensembl: ENSPPYG00000008634
Position
17:68400017..68437240
AA seq 1752 aa
MAGPRPSPWARLLLAALISVSLSGTLANRCKKAPVKSCTECVRVDKDCAYCTDEMFRDRR
CNTQAELLAAGCQRENIVVMESSFQITEETQIDTTLRRSQMSPQGLRVRLRPGEEQHFEL
EVFEPLESPVDLYILMDFSNSMSDDLDNLKKMGQNLARVLSQLTSDYTIGFGKFVDKVSV
PQTDMRPEKLKEPWPNSDPPFSFKNVISLTEDVDEFRNKLQGERISGNLDAPEGGFDAIL
QTAVCTRDIGWRPDSTHLLVFSTESAFHYEADGANVLAGIMSRNDERCHLDATGTYTQYR
TQDYPSVPTLVRLLAKHNIIPIFAVTNYSYSYYEKLHTYFPVSSLGVLQEDSSNIVELLE
EAFNRIRSNLDIRALDSPRGLRTEVTSKMFQKTKTGSFHIRRGEVGVYQVQLRALEHVDG
THVCQLPEDQKGNIHLKPSFSDGLKMDVGIICDVCTCELRKEVRSARCSFNGDFMCGHCV
CSEGWSGQTCNCSTGSLSDIQPCLREDEDKPCSGRGECQCGHCVCYGEGRYEGQFCEYDN
FQCPRTSGFLCNDRGRCSMGQCVCEPGWTGPSCDCPLSNATCIDSNGGICNGRGHCECGR
CHCHQQSLYTDTICEINYSAIHPGLCEDLRSCVQCQAWGTGEKKGRTCEECNFKVKMVDE
LKRAEEVVVRCSFRDEDDDCTYSYTMEGDGAPGPNSTVLVHKKKDCPPGSFWWLIPLLLL
LLPLLALLLLLCWKYCACCKACLALLPCCNRGHMVGFKEDHYMLRENLMASDHLDTPMLR
SGSLKGRDVVRWKVTNNMQRPGFATHAASINPTELVPYGLSLRLARLCTENLLKPDTREC
AQLRQEVEENLNEVYRQISGVHKLQQTKFRQQPNAGKKQDHTIVDTVLMAPRSAKPALLK
LTEKQVEQRAFHDLKVAPGYYTLTADQDARGMVEFQEGVELVDVRVPLFIRPEDDEEKQL
LVEAIDVPAGTATLGRRLVNITIIKEQARDVVSFEQPEFSVSRGDQVARIPVIRRVLDGG
KSQVSYRTQDGTAQGNRDYIPMEGELLFQPGEAWKELQVKLLELQEVDSLLRGRQVRRFH
VQLSNPKFGAHLGQPHSTTIIIRDPDELDRSFTSQMLSSQPPPHGDLGAPQNPNAKAAGS
RKIHFNWLPPSGKPMGYRVKYWIQGDSESEAHLLDSKVPSVELTNLYPYCDYEMKVCAYG
AEGEGPYSSLVSCRTHQEVPSEPGRLAFNVVSSTVTQLSWAEPAETNGEITAYEVCYGLV
NDDNRPIGPMKKVLVDNPKNRMLLIENLRESQPYRYTVKARNGAGWGPEREAIINLATQP
KRPMSIPIIPDIPIVDAQSGEDYDSFLMYSDDVLRSPSGSQRPSVSDDTEHLVNGRMDFA
FPGSTNSLHGMTTTSTAAYGTHLSPHVPHRVLSTSSTLTRDYNSLTRSEHSHSTTLPRDY
STLTSVSSHDSRLTAGVPDTPTRLVFSALGPTSLRVSWQEPRCERPLQGYSVEYQLLNGG
ELHRLNIPNPAQTSVVVEDLLPNHSYVFRVRAQSQEGWGREREGVITIESQVHPQSPLCP
LPGSAFTLSTPSAPGPLVFTALSPDSLQLSWERPRRPNGDIIGYLVTCEMAQGGGPATTF
RVDGDSPESRLTVPGLSENVPYKFKVQARTTEGFGPEREGIITIESQDGGPFPQLGSHAG
LFQHPLQSEYSSITTTHTSATEPFLVDGLTLGAQHLEAGGSLTRHVTQEFVSRTLTTSGT
LSTQVDQQFFQT
NT seq 5259 nt   +upstreamnt  +downstreamnt
atggcagggccacgccccagcccatgggccaggctgctactggcagccttgatcagcgtc
agcctctctgggaccttggcaaaccgctgcaagaaggccccagtgaagagctgcacggag
tgtgtccgtgtggataaggactgcgcctactgcacggacgagatgttcagggaccggcgc
tgcaacacccaggcggagctgctggccgcgggctgccagcgggagaacatcgtggtcatg
gagagcagcttccagatcacagaggagacccagattgacaccaccctgcggcgcagccag
atgtccccccagggcctgcgggtccgtctgcggcccggtgaggagcagcactttgagctg
gaggtgtttgagcccctggagagccctgtggacctgtacatcctcatggacttctccaac
tccatgtccgatgatctggacaacctcaagaagatggggcagaacctggctcgggtcctg
agccagctcaccagcgactacactattggatttggcaagtttgtggacaaagtcagcgtc
ccgcagacggacatgaggcctgagaagctgaaggagccctggcccaacagtgaccccccc
ttctccttcaagaacgtcatcagcctgacagaagatgtggatgagttccggaataaactg
cagggagagcggatctcaggcaacctggatgctcctgagggcggcttcgatgccatcctg
cagacggccgtgtgcacgagggacattggctggcgcccagacagcacccacctgctggtc
ttctccaccgagtcagccttccactatgaggccgacggcgccaacgtgctggctggcatc
atgagccgcaacgatgaacggtgccacctggatgccacgggcacctacacccagtacagg
acacaggactacccgtcggtgcccaccctggtgcgcctgctcgccaagcacaacatcatc
cccatttttgctgtcaccaactactcctatagctactacgagaagcttcacacctatttc
cctgtctcctcgctgggggtgctgcaggaggactcgtccaacatcgtggagctgctggag
gaggccttcaatcgaatccgctccaacctggacatccgggccctagacagcccccgaggc
cttcggacagaggtcacctccaagatgttccagaagacgaagactgggtcctttcacatc
cggcggggggaagtgggtgtataccaggtgcagctgcgggccctcgagcacgtggatggg
actcatgtgtgccagctgccggaggaccagaagggcaacatccatctgaaaccttccttc
tccgatggcctcaagatggacgtgggcatcatctgtgacgtgtgcacctgcgagctgcga
aaagaggtgcggtcagctcgctgcagcttcaacggagacttcatgtgtggacactgtgtg
tgcagtgagggctggagtggccagacctgcaactgctccaccggctctctgagtgacatt
cagccctgcctgcgggaggacgaggacaagccgtgctccggccgtggcgagtgccagtgc
gggcactgtgtgtgctacggcgaaggccgctatgagggtcagttctgcgagtatgacaac
ttccagtgtccccgcacttccgggttcctctgcaatgaccgaggacgctgctccatgggc
cagtgtgtgtgtgagcctggttggacaggcccaagctgtgactgtcccctcagcaatgcc
acctgcatcgacagcaatgggggcatctgcaatggacgtggccactgtgagtgtggccgc
tgccactgccaccagcagtcgctctacacggacaccatctgcgagatcaactactcggcg
atccacccgggcctctgcgaggacctacgctcctgcgtgcagtgccaggcgtggggcacc
ggggagaagaaggggcgcacgtgtgaggaatgcaacttcaaggtcaagatggtggacgag
cttaagagagccgaggaggtggtggtgcgctgctccttccgggacgaggatgacgactgc
acctacagctacaccatggaaggcgacggcgcccctgggcccaacagcactgtcctggtg
cacaagaagaaggactgccctccaggctccttctggtggctcatccccctgctcctcctc
ctcctgccgctcctggccctgctactgctactatgctggaagtactgcgcctgctgcaag
gcctgcctggcacttctcccttgctgcaaccgaggtcacatggtaggctttaaggaagac
cactacatgctgcgggagaacctgatggcctcagaccacctggacacacccatgctgcgt
agcgggagcctcaagggccgtgacgtggtccgctggaaggtcaccaacaacatgcaacgg
cctggctttgccactcatgctgccagcatcaaccccacagagctggtgccctacgggctg
tccttgcgcctggcccgcctttgcaccgagaacctgctgaagcccgacactcgggaatgc
gcccagctgcgccaggaggtggaggagaacctgaacgaggtctacaggcagatctccggt
gtacacaagctccagcagaccaagttccggcagcagcccaatgctgggaaaaagcaagac
cacaccattgtggacacagtgctgatggcaccccgctcggccaagccggccctgctgaag
cttacagagaagcaggtggaacagagggccttccacgacctcaaggtggcccctggctac
tacaccctcactgcagaccaggacgcccggggcatggtggagttccaggagggcgtggag
ctggtggacgtacgggtgcccctctttatccggcctgaggatgacgaggagaagcagctg
ctggtggaggccatcgatgtgcccgcgggcactgccaccctcggccgccgcctggtaaac
atcaccatcatcaaggagcaagccagagacgtggtgtcctttgagcagcctgagttctcg
gtcagccgcggggaccaggtggcccgcatccctgtcatccggcgcgtcctggatggcggg
aagtcccaggtctcctaccgcacacaggatggcaccgcgcagggcaaccgggactacatc
cccatggagggcgagctgctgttccagcctggggaggcctggaaagagctgcaggtgaag
ctcctggagctgcaagaggttgactccctcctgcggggccgccaggtccgccgtttccac
gtccagctcagcaaccctaagtttggggcccacctgggccagccccactccaccaccatc
atcatcagggacccagatgaactggaccggagcttcacgagtcagatgttgtcatcacag
ccaccccctcacggcgacctgggcgccccgcagaaccccaatgctaaggccgctgggtcc
aggaagatccatttcaactggctgcccccttctggcaagccaatggggtacagggtaaag
tactggattcagggtgactccgagtccgaagcccacctgctcgacagcaaggtgccctca
gtggagctcaccaacctgtacccgtattgcgactatgagatgaaggtgtgcgcctacggg
gctgagggcgagggaccctacagctccctggtgtcctgccgcacccaccaggaagtgccc
agcgagccagggcgtctggccttcaatgtcgtctcctccacggtgacccagctgagctgg
gctgagccagccgagaccaacggtgagatcacagcctacgaggtctgctatggcctggtc
aacgatgacaaccgacctatcgggcccatgaagaaggtgctggttgacaaccctaagaac
cggatgctgctcattgagaaccttcgggagtcccagccctaccgctacacggtgaaggcg
cgcaatggggccggctgggggcccgagcgggaggccatcatcaacctggcgacccagccc
aagaggcccatgtccatccccatcattcctgacatccctatcgtggacgcccagagcggg
gaggactacgacagcttccttatgtacagcgatgacgttctacgctctccatctggcagc
cagaggcccagcgtctccgatgacactgagcacctggtgaatggccggatggactttgcc
ttcccgggcagcaccaactccctgcatgggatgaccacgaccagcactgctgcctatggc
acccacctgagcccacacgtgccccaccgcgtgctaagcacatcctccacccttacacgg
gactacaactcgctgacccgctcggaacactcacactcgaccacactgcccagggactac
tccaccctcacctccgtctcctcccacgactctcgcctgactgctggtgtgcccgacacg
cccacccgcctggtgttctctgccctggggcccacatctctcagagtgagctggcaggag
ccgcggtgcgagcggccgctgcagggctacagcgtggagtaccagctgctgaacggcggt
gagctgcatcggctcaacatccccaaccctgcccagacctcggtggtggtagaagacctc
ctgcccaaccactcctacgtgttccgcgtgcgggcccagagccaggaaggctggggccga
gagcgtgagggcgtcatcaccattgaatcccaggtgcacccgcagagcccactctgtccc
ctgccaggctccgccttcactttgagcactcccagtgccccaggcccactggtgttcact
gccctgagcccagactcgctgcagctgagctgggagcggccacggaggcccaatggggat
atcattggctacctggtgacctgtgagatggcccaaggaggagggccagccaccacattc
cgggtggatggagacagccccgagagccggctgaccgtgccgggcctcagtgagaacgtg
ccctacaagttcaaggtgcaggccaggaccactgaaggcttcgggccagagcgcgagggc
atcatcaccatagagtcccaggatggcggacccttcccgcagctgggcagccatgccggg
ctcttccagcacccgctgcaaagcgagtacagcagcatcaccaccacccacaccagcgcc
accgagcccttcctagtggacgggctgaccctgggggcccagcacctagaggcaggtggc
tccctcacccggcatgtgacccaggagtttgtgagccggacgctgaccaccagcggaacc
ctcagcacccaggtggaccaacagttcttccaaacctga

  All links  
Ontology (4)   
   KEGG BRITE (4)   
Pathway (9)   
   KEGG PATHWAY (9)   
Genome (1)   
   KEGG GENOME (1)   
Gene (5)   
   KEGG ORTHOLOGY (1)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   Ensembl (1)   
   OC (1)   
Protein sequence (9)   
   RefSeq(pep) (9)   
DNA sequence (9)   
   RefSeq(nuc) (9)   
Protein domain (9)   
   Pfam (9)   
All databases (46)   

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