KEGG   Pongo abelii (Sumatran orangutan): 100457650Help
Entry
100457650         CDS       T01416                                 

Definition
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2-like
Orthology
K05859  
phosphatidylinositol phospholipase C, gamma-2 [EC:3.1.4.11]
Organism
pon  Pongo abelii (Sumatran orangutan)
Pathway
Inositol phosphate metabolism
Metabolic pathways
ErbB signaling pathway
Ras signaling pathway
Calcium signaling pathway
NF-kappa B signaling pathway
HIF-1 signaling pathway
Phosphatidylinositol signaling system
VEGF signaling pathway
Osteoclast differentiation
Platelet activation
Natural killer cell mediated cytotoxicity
B cell receptor signaling pathway
Fc epsilon RI signaling pathway
Fc gamma R-mediated phagocytosis
Leukocyte transendothelial migration
Neurotrophin signaling pathway
Inflammatory mediator regulation of TRP channels
Thyroid hormone signaling pathway
Epstein-Barr virus infection
Pathways in cancer
Proteoglycans in cancer
MicroRNAs in cancer
Glioma
Non-small cell lung cancer
Module
Inositol phosphate metabolism, PI=> PIP2 => Ins(1,4,5)P3 => Ins(1,3,4,5)P4
Brite
KEGG Orthology (KO) [BR:pon00001]
 Metabolism
  Carbohydrate metabolism
   00562 Inositol phosphate metabolism
    100457650
 Environmental Information Processing
  Signal transduction
   04014 Ras signaling pathway
    100457650
   04012 ErbB signaling pathway
    100457650
   04370 VEGF signaling pathway
    100457650
   04064 NF-kappa B signaling pathway
    100457650
   04066 HIF-1 signaling pathway
    100457650
   04020 Calcium signaling pathway
    100457650
   04070 Phosphatidylinositol signaling system
    100457650
 Organismal Systems
  Immune system
   04611 Platelet activation
    100457650
   04650 Natural killer cell mediated cytotoxicity
    100457650
   04662 B cell receptor signaling pathway
    100457650
   04664 Fc epsilon RI signaling pathway
    100457650
   04666 Fc gamma R-mediated phagocytosis
    100457650
   04670 Leukocyte transendothelial migration
    100457650
  Endocrine system
   04919 Thyroid hormone signaling pathway
    100457650
  Nervous system
   04722 Neurotrophin signaling pathway
    100457650
  Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    100457650
  Development
   04380 Osteoclast differentiation
    100457650
 Human Diseases
  Cancers
   05200 Pathways in cancer
    100457650
   05206 MicroRNAs in cancer
    100457650
   05205 Proteoglycans in cancer
    100457650
   05214 Glioma
    100457650
   05223 Non-small cell lung cancer
    100457650
  Infectious diseases
   05169 Epstein-Barr virus infection
    100457650
Enzymes [BR:pon01000]
 3. Hydrolases
  3.1  Acting on ester bonds
   3.1.4  Phosphoric-diester hydrolases
    3.1.4.11  phosphoinositide phospholipase C
     100457650
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif Motif
Other DBs
NCBI-GI: 
NCBI-GeneID: 
Position
16
AA seq 907 aa AA seqDB search
MGKLPNQIAAVLSPQACALTPRMRSSPERADVGAVPPEQCPVSVAPGPSCPGLSVGQMQR
CVLPLPSCPPSSDCSFPVILSIEEHCSVEQQRHMAKVFKEVFGDLLLTKPTEASADQLPS
PSQLREKIIIKKWTRHYCAIADAKLSFSDDIEQTMEEEVPQDIPPTELHFGEKWFHKKVE
KRTSAEKLLQEYCMETGGKDGTFLVRESETFPNDYTLSFWRSGRVQHCRIRSTMEGGTLK
YYLTDNLTFSSIYALIQHYRETHLRCAEFELRLTDPVPNPNPHESKPWYYDSLSRGEAED
MLMRIPRDGAFLIRKREGSDSYAITFRARGKVKHCRINRDGRHFVLGTSAYFESLVELVS
YYEKHSLYRKMRLRYPVTPELLERYNMERDINSLYDVSRMYVDPSEINPSMPQRTVKALY
DYKAKRSDELSFCRGALIHNVSKEPGGWWKGDYGTRIQQYFPSNYVEDISTADFEELEKQ
IIEDNPLGSLCRGILDLNTYNVVKAPQGKNQKSFVFILEPKKQGDPPVEFATDRVEELFE
WFQSIREITWKIDTKENNMKYWEKNQSIAIELSDLVVYCKPTSKTKDNLENPDFREIRSF
VETKADSIIRQKPVDLLKYNQKGLTRVYPKGQRVDSSNYDPFRLWLCGSQMVALNFQTAD
KYMQMNHALFSLNGRTGYVLQPESMRTEKYDPMPPESQRKILMTLTVKVLGARHLPKPGR
SIACPFVEVEICGAEYDNNKFKTTVVNDNGLSPIWAPTQEKVTFEIYDPNLAFLRFVVYE
EDMFSDPNFLAHATYPIKAIKSGFRSVPLKNGYSEDIELASLLVFCEMRPVLESEEELYS
SCRQLRRRQEELNNQLFLYDTHQNLRNANRDALVKEFNVNENQLQLYQEKCNKRLREKRV
SNSKFYS
NT seq 2724 nt NT seq  +upstreamnt  +downstreamnt
atggggaagctcccgaatcagattgcagctgttctgagtccccaggcttgtgccctcaca
cccaggatgaggtcgtctcctgagagggcagatgtcggggctgtaccccccgagcagtgc
ccggtttctgtcgccccagggccgagctgccccggcctctctgtggggcagatgcagagg
tgcgtgctccccctgccaagctgcccaccctcttccgactgcagcttcccagtgatcctg
tccatcgaggagcactgcagcgtggagcagcagcgtcacatggccaaggtcttcaaggaa
gtgtttggcgacctgctgctgacgaagcccacggaggccagcgctgaccagctgccctcg
cccagccagctgcgggagaagatcatcatcaagaaatggactcgacactactgcgccatc
gccgatgccaagctgtccttcagtgatgacattgaacagactatggaggaggaggtgccc
caggatataccccccacagagctacattttggggagaaatggttccacaagaaggtggag
aagaggacgagtgccgagaagttgctgcaggaatactgcatggagacggggggcaaggat
ggcaccttcctggttcgggagagcgagaccttccccaatgactacaccctgtccttctgg
cggtcaggccgggtccagcactgccggatccgctccaccatggagggtgggaccctgaaa
tactacctgactgacaacctcaccttcagcagcatctacgccctcatccagcactaccgc
gagacgcacctgcgctgcgcagagtttgagctgcggctcacggaccctgtgcccaacccc
aacccccacgagtccaagccgtggtactacgacagcctgagccgcggagaggcagaggac
atgctgatgaggattccccgggatggagccttcctgatccggaagcgagaggggagcgac
tcctacgccatcaccttcagggctaggggcaaggtgaagcattgtcgcatcaaccgggac
ggccggcactttgtgctggggacctccgcctattttgagagtctggtggagcttgtcagt
tactatgagaagcattcactctaccgaaagatgagactgcgctaccctgtgacccctgag
ctcctggagcgctacaatatggaaagagatataaactccctctacgacgtcagcagaatg
tatgtggatcccagtgaaatcaatccgtccatgcctcagagaaccgtgaaagctctgtat
gactacaaagccaagcgaagcgacgagctgagcttctgccgtggtgccctcatccacaat
gtctccaaggagcccgggggctggtggaaaggagactatggaaccaggatccagcagtac
ttcccatccaactacgtcgaggacatctcaactgcagacttcgaggagctagaaaagcag
attattgaagacaatcccttagggtctctttgcagaggaatattggacctcaatacctat
aacgttgtgaaagcccctcagggaaaaaaccagaagtcctttgtcttcatcctggagccc
aagaagcagggcgatcctccggtggagtttgccacagacagagtggaggaactctttgag
tggtttcagagcatccgagagatcacctggaagattgacaccaaggagaacaacatgaag
tactgggagaagaaccagtccatcgccatcgagctctctgacctggttgtctactgcaaa
ccaaccagcaaaaccaaggacaacttagaaaatcctgacttccgagaaatccgctccttt
gtggagacgaaggctgacagcatcatcagacagaagcccgtcgacctcctgaaatacaat
caaaagggcctgacccgcgtctacccaaagggacaaagagttgactcttcaaactacgac
cccttccgcctctggctgtgcggttctcagatggtggcactcaatttccagacagcagat
aagtacatgcagatgaatcacgccttgttttctctcaatgggcgcacgggctacgttctg
cagcctgagagcatgaggacagagaaatatgacccgatgccacccgagtcccagaggaag
atcctgatgacgctgacagtcaaggttctcggtgctcgccatctccccaaacctggacga
agtattgcctgtccctttgtagaggtggagatctgtggagctgagtatgacaacaacaag
ttcaagacaacggttgtgaatgataatggcctcagccctatctgggctccaacacaggag
aaggtgacatttgaaatttatgacccaaacctggcatttctgcgctttgtggtttacgaa
gaagatatgttcagtgatcccaactttcttgctcatgccacttaccccattaaagcaatc
aaatcaggattcaggtccgttcctctgaagaatgggtacagcgaggacatagagctggct
tccctcctggttttctgtgagatgcggccagtcctggaaagtgaggaggaactttactcc
tcctgtcgccagctgaggaggcggcaagaagaattgaacaaccagctctttctgtatgac
acacaccagaacttgcgcaatgccaaccgggatgccctggttaaagagttcaatgttaat
gagaaccagctccagctgtaccaggagaaatgcaacaagaggttaagagagaagagagtc
agcaacagcaagttttactcatag

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