KEGG   Pongo abelii (Sumatran orangutan): 100457992Help
Entry
100457992         CDS       T01416                                 
Gene name
EIF2AK4
Definition
eukaryotic translation initiation factor 2 alpha kinase 4
Orthology
K16196  
eukaryotic translation initiation factor 2-alpha kinase 4 [EC:2.7.11.1]
Organism
pon  Pongo abelii (Sumatran orangutan)
Pathway
Protein processing in endoplasmic reticulum
Hepatitis C
Measles
Influenza A
Herpes simplex infection
Epstein-Barr virus infection
Class
Genetic Information Processing; Folding, sorting and degradation; Protein processing in endoplasmic reticulum [PATH:pon04141]
Human Diseases; Infectious diseases; Measles [PATH:pon05162]
Human Diseases; Infectious diseases; Influenza A [PATH:pon05164]
Human Diseases; Infectious diseases; Hepatitis C [PATH:pon05160]
Human Diseases; Infectious diseases; Herpes simplex infection [PATH:pon05168]
Human Diseases; Infectious diseases; Epstein-Barr virus infection [PATH:pon05169]
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif Motif
Other DBs
NCBI-GI: 
NCBI-GeneID: 
Position
15
AA seq 1575 aa AA seqDB search
MAGGRGAPGRGRDEPPESYPQRQDHELQALEAIYGADFQDLRPDACGPVKKPPEINLVLY
PQGLTGEEVYVKVDLRVKCPPTYPDVVPEIELKNAKGLSNESVNLLKSRLEELAKKHCGE
VMIFELAYHVQSFLSEHNKPPPKSFHEEMLERRAQEEQQRLLEAKRKEEQEQREILHEIQ
RRKEEIKEEKKRKEMAKQERLEIANLSNQDHTSKKDPGGHRTTAILHGGSPDFVGNGKHR
ANSSGRSRRERQYSVCNSEDSPGSCEILYFNMGSPDQLMVHKGKCIGSDEQLGKLVYNAL
ETATGGFVLLYEWVLQWQKKMGPFLTSQEKEKIDKCKKQIQGTETEFNSLIKLSHPNVVR
YLAMNLKEQDDSIVVDILVEHISGVSLAAHLSHSGPIPVHQLRRYTAQLLSGLDYLHSNS
VVHKVLSASNVLVDAEGTVKITDYSISKRLADICKEDVFEQTRVRFSDNALPYKTGKKGD
VWRLGLLLLSLSQGQECGEYPVTIPSDLPADFQDFLKKCVCLDDKERWSPQQLLKHSFIN
PQPKMPLVEQSPEDSGGQDYVETVIPSNRLPSAAFFSETQRQFSRYFIEFEELQLLGKGA
FGAVIKVQNKLDGCCYAVKRIPINPASRQFRRIKGEVTLLSRLHHENIVRYYNAWIERHE
RPAGPGTPPPDSGPLAKDDRAARGQPASDTDGLDSVEAAAPPPILSSSVEWSTSGERSAS
ARFPATGPGSSDDEDDDEDEHGGVFSQSFLPASDSESDIIFDNEDENSKSQNQDEDCNEK
NGCHESEPSVTTEAVHYLYIQMEYCEKSTLRDTIDQGLYRDTVRLWRLFREILDGLAYIH
EKGMIHRDLKPVNIFLDSDDHVKIGDFGLATDHLAFSVSHLTGMVGTALYVSPEVQGSTK
SAYNQKVDLFSLGIIFFEMSYHPMVTASERIFVLNQLRDPTSPKFPEDFDDGEHAKQKSV
ISWLLNHDPAKRPTATELLKSELLPPPQMEESELHEVLHHTLTNVDGKAYRTMMAQIFSQ
RISPAIDYTYDSDILKGNFSIRTAKMQQHVCETIIRIFKRHGAVQLCTPLLLPRNRQIYE
HNEAALFMDHSGMLVMLPFDLRIPFARYVARNNILNLKRYCIERVFRPRKLDRFHPKELL
ECAFDIVTSTTNSFLPTAEIIYTIYEIIQEFPALQERNYSIYLNHTMLLKAILLHCGIPE
DKLSQVYIILYDAVTEKLTRREVEAKFCNLSLSSNSVLINLGLVYKVQQHNGIIFQFVAF
IKRRQRAVPEILAAGGRYDLLIPQFRGPQALGPVPTAIGVSIAIDKISAAVLNMEEPVTI
SSCDLLVVSVGQMSMSRAINLTQKLWTAGITAEIMYDWSQSQEELQEYCRHHEITYVALV
SDKEGSHVKVKSFEKERQTEKRVLETELVDHVLQKLRTKVGDERNGRDASDNLAVQNLKG
SFSNASGLFEIHGATVVPIVSVLAPEKLSASTRRRYETQVQTRLQTSLANLHQKSSEIEI
LAVDLPKETILQFLSLEWDADEQAFNTTVKQLLSRLPKQRYLKLVCDEIYNIKVEKKVSV
LFLYSYRDDYYRILF
NT seq 4728 nt NT seq  +upstreamnt  +downstreamnt
atggctgggggccgtggggcccccggacgcggccgggacgagcctccggagagctacccg
caacgacaggaccacgagctacaggccctggaggccatctacggcgcggacttccaagac
ctgcggccggacgcttgcggaccggtcaaaaagccccctgaaatcaatttagttttgtac
cctcaaggcctaaccggtgaagaagtatatgtaaaagtggatttgagggttaaatgccca
cctacctatccagatgtagttcctgaaatagagttaaaaaatgccaaaggtctatcaaat
gaaagtgttaatttgttaaaatctcgccttgaagaactggccaagaaacactgtggggag
gtgatgatctttgaactggcttaccatgtgcagtcatttctcagcgagcataacaagccc
cctcccaagtcttttcacgaagaaatgctggaaaggcgggctcaagaggagcagcagagg
ctgttggaggccaagcggaaagaagagcaggagcaacgtgaaatcctacatgagattcag
agaaggaaagaagagataaaagaagagaaaaaaaggaaagaaatggctaagcaggaacgt
ttggaaattgctaatttgtcaaaccaagatcatacctctaagaaggacccaggaggacac
agaacgactgccattctacatggaggctctcctgactttgtaggaaatggtaaacatcgg
gcaaactcctcaggaaggtctaggcgagaacgtcagtattctgtatgtaatagtgaagat
tctcctggctcttgtgaaattctgtatttcaatatggggagtcctgatcagctcatggta
cacaaagggaaatgtattggcagtgatgaacaacttggaaaattagtctacaatgctttg
gaaacagccactggtggctttgtcttgttgtatgagtgggtccttcagtggcagaaaaaa
atgggtccattccttaccagtcaagaaaaagagaagattgataagtgcaaaaagcagatt
caaggaacagaaacagaattcaactcactgataaaattgagccatccaaatgtagtacgc
taccttgcaatgaatctcaaagagcaagacgactccatcgtggtggacattttagtggag
cacattagtggggtctctcttgctgcacacctgagccactcaggccccatccctgtgcat
caacttcgcaggtacacagctcagctcctgtcgggccttgattatctgcacagcaattct
gtggtgcataaggtcctgagtgcatctaatgtcttggtggatgcagaaggcaccgtcaag
attacggactatagcatttctaagcgcctcgcagacatttgcaaggaggatgtgtttgag
caaacccgagttcgttttagtgacaatgctctgccttataaaacggggaagaaaggagat
gtttggcgtcttggccttctgctgctgtccctcagccaagggcaggaatgtggagagtac
cctgtgaccatccctagtgacttaccagctgactttcaagattttctaaagaaatgtgtg
tgcttggatgacaaggaaagatggagtccccagcagttgttgaaacacagctttataaat
ccccagccaaaaatgcctctagtggaacaaagtcctgaagattctggaggacaagattat
gttgagactgttattcctagcaaccggctacccagtgctgccttctttagtgagacacag
agacagttttccagatacttcattgagtttgaagaattacagcttcttggtaaaggagct
tttggagctgtcatcaaggtgcagaacaagttggacggctgctgctacgcagtgaagcgc
atccccatcaacccggccagccggcagttccgcaggatcaagggcgaggtgacactgctg
tcacggctgcaccatgaaaacattgtgcgctactacaacgcctggattgagcggcacgag
cggccggcgggaccggggacgccgcccccggactccgggcccctggccaaggatgaccga
gctgcacgcgggcagccggcgagcgacacagacggcctggacagcgtagaagccgccgcg
ccgccacccatcctcagcagctcggtggagtggagcacttcgggcgagcgctcggccagt
gcccgtttccctgccaccggcccgggctccagcgatgacgaggacgacgacgaggacgag
cacggtggcgtcttctcccagtccttcctgcctgcttcagattctgaaagtgacattatc
tttgacaatgaagatgagaacagtaaaagtcagaatcaggatgaagactgcaatgaaaag
aatggctgccatgaaagtgagccatcagtgacgaccgaggctgtgcactacctatacatc
cagatggagtactgtgagaagagcactttacgagacaccattgaccagggactgtatcga
gacaccgtcagactctggaggctttttcgagagattctggatggattagcttatatccat
gagaaaggaatgattcaccgggatttgaagcctgtcaacatttttttggattctgatgac
catgtgaaaataggtgattttggtttggcgacagaccatctagccttttctgtaagtcac
ttaactgggatggttggcactgctctctatgtaagcccagaggtccaaggaagcaccaaa
tctgcatacaaccagaaagtggatctcttcagcctgggaattatcttctttgagatgtcc
tatcaccccatggtcacagcttcagaaaggatctttgttctcaaccaactcagagatcct
acttcgcctaagtttccagaagactttgatgatggagagcatgcaaagcagaaatcagtc
atctcctggctgttgaaccacgatccagcaaaacggcccacagccacagaactgctcaag
agtgagctgctgcccccaccccagatggaggagtcagagctgcatgaagtactgcaccac
acactgaccaacgtggatgggaaggcctaccgcaccatgatggcccagatcttctcccag
cgcatctcccctgccatcgattatacctatgacagtgacatactgaagggcaacttctca
atccgtacagccaagatgcagcagcacgtgtgtgaaaccatcatccgcatctttaagaga
cacggagctgttcagttgtgtaccccactactacttccccgaaacagacaaatatatgag
cacaacgaagctgccctattcatggaccacagcgggatgctggtgatgcttccttttgac
ctgcggatcccttttgcaagatatgtggcaagaaataatatattgaatttaaaacgatac
tgcatagaacgtgtgttcaggccgcgcaaattagatcgatttcatcccaaagaacttctg
gagtgtgcatttgatattgtcacttctaccaccaacagctttctgccaactgctgaaatt
atctacactatctatgaaatcatccaagagtttccagcacttcaggaaagaaattacagt
atttatttgaaccataccatgttattgaaagcaatactcttacactgtgggatcccagaa
gataaactcagtcaagtctacattattctgtatgatgctgtgacagagaagctgacgagg
agagaagtggaagctaaattttgtaatctgtctttgtcttctaatagtgtcttgatcaat
ttgggcttggtttacaaggtgcagcagcacaatggaatcatcttccagtttgtagcgttc
atcaaacgaaggcaaagggctgtacctgaaatccttgcagctggaggcagatatgacctg
ctgattccccagtttagagggccacaagctctggggccagttcccactgccattggggtc
agtatagctatagacaagatatctgctgctgtcctcaacatggaggaacctgttacaata
agctcttgtgacctcctggttgtaagtgttggccagatgtctatgtccagggccatcaac
ctaacgcagaaactctggacagcaggcatcacagcagaaatcatgtacgactggtcacag
tcccaagaggaattacaagagtactgcagacatcacgaaatcacctatgtggcccttgtc
tcggataaagaaggaagccatgtcaaggttaagtctttcgagaaggaaaggcagacggag
aagcgtgtgctggagactgaacttgtggaccacgtactgcagaaactgaggactaaagtc
ggtgatgaaaggaatggcagagacgcttccgataatcttgcagtgcaaaatctgaagggg
tcattttctaatgcttcaggtttgtttgaaatccatggagcaacagtggttcccattgtg
agtgtgctagccccggagaagctgtcagccagcactaggaggcgctatgaaactcaggta
caaactcgacttcagacctcccttgccaacttacatcagaaaagcagtgaaattgaaatt
ctggctgtggatctacccaaagaaacaatattacagtttttatcattagagtgggatgct
gatgaacaggcatttaacacaactgtaaagcagctgctgtcacgcctgccaaagcaaaga
tacctcaaattagtctgtgatgaaatttataacatcaaagtagaaaaaaaggtgtctgtg
ctatttctgtacagctatagagatgactactacagaatcttattttaa
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