KEGG   Pongo abelii (Sumatran orangutan): 100458733Help
Entry
100458733         CDS       T01416                                 

Gene name
SOS1
Definition
son of sevenless homolog 1 (Drosophila)
Orthology
K03099  
son of sevenless
Organism
pon  Pongo abelii (Sumatran orangutan)
Pathway
MAPK signaling pathway
ErbB signaling pathway
Ras signaling pathway
Chemokine signaling pathway
FoxO signaling pathway
PI3K-Akt signaling pathway
Dorso-ventral axis formation
Focal adhesion
Gap junction
Jak-STAT signaling pathway
Natural killer cell mediated cytotoxicity
T cell receptor signaling pathway
B cell receptor signaling pathway
Fc epsilon RI signaling pathway
Neurotrophin signaling pathway
Regulation of actin cytoskeleton
Insulin signaling pathway
GnRH signaling pathway
Estrogen signaling pathway
Prolactin signaling pathway
Alcoholism
Hepatitis C
Pathways in cancer
Proteoglycans in cancer
MicroRNAs in cancer
Renal cell carcinoma
Endometrial cancer
Glioma
Prostate cancer
Chronic myeloid leukemia
Acute myeloid leukemia
Non-small cell lung cancer
Choline metabolism in cancer
Brite
KEGG Orthology (KO) [BR:pon00001]
 Environmental Information Processing
  Signal transduction
   04014 Ras signaling pathway
    100458733 (SOS1)
   04010 MAPK signaling pathway
    100458733 (SOS1)
   04012 ErbB signaling pathway
    100458733 (SOS1)
   04630 Jak-STAT signaling pathway
    100458733 (SOS1)
   04068 FoxO signaling pathway
    100458733 (SOS1)
   04151 PI3K-Akt signaling pathway
    100458733 (SOS1)
 Cellular Processes
  Cell motility
   04810 Regulation of actin cytoskeleton
    100458733 (SOS1)
  Cellular commiunity
   04510 Focal adhesion
    100458733 (SOS1)
   04540 Gap junction
    100458733 (SOS1)
 Organismal Systems
  Immune system
   04650 Natural killer cell mediated cytotoxicity
    100458733 (SOS1)
   04660 T cell receptor signaling pathway
    100458733 (SOS1)
   04662 B cell receptor signaling pathway
    100458733 (SOS1)
   04664 Fc epsilon RI signaling pathway
    100458733 (SOS1)
   04062 Chemokine signaling pathway
    100458733 (SOS1)
  Endocrine system
   04910 Insulin signaling pathway
    100458733 (SOS1)
   04912 GnRH signaling pathway
    100458733 (SOS1)
   04915 Estrogen signaling pathway
    100458733 (SOS1)
   04917 Prolactin signaling pathway
    100458733 (SOS1)
  Nervous system
   04722 Neurotrophin signaling pathway
    100458733 (SOS1)
  Development
   04320 Dorso-ventral axis formation
    100458733 (SOS1)
 Human Diseases
  Cancers
   05200 Pathways in cancer
    100458733 (SOS1)
   05231 Choline metabolism in cancer
    100458733 (SOS1)
   05206 MicroRNAs in cancer
    100458733 (SOS1)
   05205 Proteoglycans in cancer
    100458733 (SOS1)
   05214 Glioma
    100458733 (SOS1)
   05221 Acute myeloid leukemia
    100458733 (SOS1)
   05220 Chronic myeloid leukemia
    100458733 (SOS1)
   05211 Renal cell carcinoma
    100458733 (SOS1)
   05215 Prostate cancer
    100458733 (SOS1)
   05213 Endometrial cancer
    100458733 (SOS1)
   05223 Non-small cell lung cancer
    100458733 (SOS1)
  Substance dependence
   05034 Alcoholism
    100458733 (SOS1)
  Infectious diseases
   05160 Hepatitis C
    100458733 (SOS1)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif Motif
Other DBs
NCBI-GI: 
NCBI-GeneID: 
Position
2A
AA seq 1318 aa AA seqDB search
MSSYRKPFQVDLYPSTSPQMQTPYIWCLLEGGVENDHCETMPESSETFASSKFEQLERVQ
KSFPHPIDKWAIADAQSAIEKRKRRNPLSLPVEKIHPLLKEVLGYKIDHQVSVYIVAVLE
YISADILKLVGNYVRNIRHYEITKQDIKVAMCADKVLMDMFHQDVEDINVLSLTDEEPST
SGEQTYYDLVKAFMAEIRQYIRELNLIIKVFREPFVSNSKLFSANDVENIFSRIVDIHEL
SVKLLGHIEDTVEMTDEGSPHPLVGSCFEDLAEELAFDPYESYARDILRPGFHDRFLSQL
SKPGAALYLQSIGEGFKEAVQYVLPRLLLAPVYHCLHYFELLKQLEEKSEDQEDKECLKQ
AITALLNVQSGMEKICSKSLAKRRLSESACRFYSQQMKGKQLAIKKMNEIQKNIDGWEGK
DIGQCCNEFIMEGTLTRVGAKHERHIFLFDGLMICCKSNHGQPRLPGASNAEYRLKEKFF
MRKVQINDKDDTNEYKHAFEIILKDENSVIFSAKSAEEKNNWMAALISLQYRSTLERMLD
VTMLQEEKEEQMRLPSADVYRFAEPDSEENIIFEENMQPKAGIPIIKAGTVIKLIERLTY
HMYADPNFVRTFLTTYRSFCKPQELLSLIIERFEIPEPEPTEADRIAIENGDQPLSAELK
RFRKEYIQPVQLRVLNVCRHWVEHHFYDFERDAYLLQRMEEFIGTVRGKAMKKWVESITK
IIQRKKIARDNGPGHNITFQSSPPTVEWHISRPGHIETFDLLTLHPIEIARQLTLLESDL
YRAVQPSELVGSVWTKEDKEINSPNLLKMIRHTTNLTLWFEKCIVETENLEERVAVVSRI
IEILQVFQELNNFNGVLEVVSAMNSSPVYRLDHTFEQIPSRQKKILEEAHELSEDHYKKY
LAKLRSINPPCVPFFGIYLTNILKTEEGNPEVLKRHGKELINFSKRRKVAEITGEIQQYQ
NQPYCLRVESDIKRFFENLNPMGNSMEKEFTDYLFNKSLEIEPRNPKPLPRFPKKYSYPL
KSPGVRPSNPRPGTMRHPTPLQQEPRKISYSRIPESETESTASAPNSPRTPLTPPPASGA
SSTTDVCSVFDSDHSSPFHSSNDTVFIQVTLPHGPRSASVSSISLTKGTDEVPVPPPVPP
RRRPESAPAESSPSKIMSKHLDSPPAIPPRQPTSKAYSPRYSISDRTSVSDPPESPPLLP
PREPVRTPDVFSSSPLHLQPPPLGKKXDHGNAFFPNSPSPFTPPPPQTPSPHGTRRHLPS
PPLTQEVDLHSIAGPPVPPRQSTSQHIPKLPPKTYKREHTHPSMHRDGPPLLENAHSS
NT seq 3957 nt NT seq  +upstreamnt  +downstreamnt
atgtcgtcctacaggaagccttttcaggttgacctgtacccatctaccagtcctcaaatg
caaacaccatacatctggtgtctactggagggtggagttgaaaatgatcattgtgaaaca
atgccagaatcttctgaaacttttgcaagcagcaaatttgaacagctggaacgtgttcaa
aaaagtttccctcatccaattgataaatgggcaatagctgatgcccaatcagctattgaa
aagaggaagcgaagaaaccctttatctctcccagtagaaaaaattcatcctttattaaag
gaggtcctaggttataaaattgaccaccaggtttctgtttacatagtagcagtcttagaa
tacatttctgcagacattttaaagctggttgggaattacgtaagaaatatacggcattat
gaaattacaaaacaagatattaaagtggcaatgtgtgctgacaaggtattgatggatatg
tttcatcaagatgtagaagatattaatgtattatctttaactgatgaagagccttccacc
tcaggagaacaaacttactatgatttggtaaaagcatttatggcagaaattcgacaatat
ataagggaactaaatctaattataaaagtttttagagagccctttgtctccaattcaaaa
ttgttttcagctaatgatgtagaaaatatatttagtcgcatagtagatatacatgaactt
agtgtaaagttactgggccatatagaagatacagtagaaatgacagatgaaggcagtccc
catccactagtaggaagctgctttgaagacttagcagaggaactggcatttgatccatat
gaatcgtatgctcgagatattttgcgacctggttttcatgatcgtttccttagtcagtta
tcaaagcctggggcagcactttatttgcagtcaataggcgaaggtttcaaagaagctgtt
caatacgttttacccaggctgcttctggcccctgtttaccactgtctccattactttgaa
cttttgaagcagttagaagaaaaaagtgaagatcaagaagacaaggaatgtttaaaacaa
gcaataacagctttgcttaatgttcagagtggtatggaaaaaatatgttctaaaagtctt
gcaaaacgaagactgagtgaatctgcatgtcggttttatagtcagcaaatgaaggggaaa
caactagcaatcaagaaaatgaacgagattcagaagaatattgatggttgggagggaaaa
gacattggacagtgttgcaatgaatttataatggaaggaactcttacacgtgtaggagcc
aaacatgagagacacatatttctctttgatggcttaatgatttgctgtaaatcaaatcat
gggcagccaagacttcctggtgctagcaatgcagaatatcgtcttaaagaaaagtttttt
atgcgaaaggtacaaattaatgataaagatgacaccaatgaatacaaacatgcttttgaa
ataattttaaaagatgaaaatagtgttatattttctgccaagtcagctgaagagaaaaac
aattggatggcagcattgatatctttacagtaccggagtacactggaaaggatgcttgat
gtaacaatgctacaggaagagaaagaggagcagatgaggctgcctagtgccgatgtttat
agatttgcagagcctgactctgaagagaatattatatttgaagagaacatgcagcccaag
gctggaattccaattatcaaagcaggaactgttattaaacttatagagaggcttacgtac
catatgtacgcagatcccaattttgttcggacatttcttacaacatacagatccttttgc
aaacctcaagaactactgagtcttataatagaaaggtttgaaattccagagcctgagcca
acagaagctgatcgcatagctatagagaatggagatcaacccttgagtgcagaactaaaa
agatttagaaaagaatatatacagcctgtgcaactgcgagtattaaatgtatgtcggcac
tgggtagagcaccacttctatgattttgaaagagatgcatatcttttgcaacgaatggaa
gaatttattggaacagtaagaggtaaagcaatgaaaaaatgggttgaatccatcactaaa
ataatccaaaggaaaaaaattgcaagagacaatggaccaggtcataatattacatttcag
agttcacctcccacagttgagtggcatataagcagacctgggcacatagagacttttgac
ctgctcaccttacacccaatagaaattgctcgacaactcactttacttgaatcagatcta
taccgagctgtacagccatcagaattagttggaagtgtgtggacaaaagaagacaaagaa
attaactctcctaatcttctgaaaatgattcgacataccaccaacctcactctgtggttt
gagaaatgtattgtagaaactgaaaatttagaagaaagagtagctgtggtgagtcgaata
attgagattctacaagtctttcaagagttgaacaactttaatggtgtccttgaggtcgtc
agtgctatgaattcatcacctgtttacagactagaccacacatttgagcaaataccaagt
cgccagaagaaaattttagaagaagctcatgaattgagtgaagatcactataagaaatat
ttggcaaaactcaggtctattaatccaccatgtgtgcctttctttggaatttatctcact
aatatcttgaaaacagaagaaggcaaccctgaggtcctaaaaagacatgggaaagagctt
ataaactttagcaaaaggaggaaagtagcagaaataacaggagagatccagcagtaccaa
aatcagccttactgtttacgagtagaatcagatatcaaaaggttctttgaaaacttgaat
ccgatgggaaatagcatggagaaagaatttacagattatcttttcaacaaatccctagaa
atagaaccacgaaaccctaagcctctcccaagatttccaaaaaaatatagctatccccta
aaatctcctggtgttcgtccatcaaacccaagaccaggtaccatgaggcatcccacacct
ctgcagcaggagccaaggaaaattagttatagtaggatccctgaaagtgaaacagaaagt
acagcatctgcaccaaattctccaagaacaccgttaacacctccgcctgcttctggtgct
tccagtaccacagatgtttgcagtgtatttgattccgatcattcgagcccttttcactca
agcaatgataccgtctttatccaagttactctgccccatggcccaagatctgcttctgta
tcatctataagtttaaccaaaggcactgatgaagtgcctgtccctcctcctgttcctcca
cgaagacgaccagaatctgccccagcagaatcttcaccatctaagattatgtctaagcat
ttggacagtcccccagccattcctcctaggcaacccacatcaaaagcctattcaccacga
tattcaatatcagaccggacctctgtctcagaccctcctgaaagccctcccttattacca
ccacgagaacctgtgaggacacctgatgttttctcaagctcaccactacatctccaacct
ccccctttgggcaaaaaangtgaccatggcaatgccttcttcccaaacagcccttcccct
tttacaccacctcctcctcaaacaccttctcctcacggcacaagaaggcatctgccatca
ccaccattgacacaagaagtggaccttcattccattgctgggccgcctgttcctccacga
caaagcacttctcaacatatccctaaactccctccaaaaacttacaaaagggagcacaca
cacccatccatgcacagagatggaccaccactgttggagaatgcccattcttcctga

DBGET integrated database retrieval system