KEGG   Pongo abelii (Sumatran orangutan): 100458733Help
Entry
100458733         CDS       T01416                                 

Gene name
SOS1
Definition
son of sevenless homolog 1 (Drosophila)
Orthology
K03099  
son of sevenless
Organism
pon  Pongo abelii (Sumatran orangutan)
Pathway
MAPK signaling pathway
ErbB signaling pathway
Ras signaling pathway
Chemokine signaling pathway
FoxO signaling pathway
PI3K-Akt signaling pathway
Dorso-ventral axis formation
Focal adhesion
Gap junction
Jak-STAT signaling pathway
Natural killer cell mediated cytotoxicity
T cell receptor signaling pathway
B cell receptor signaling pathway
Fc epsilon RI signaling pathway
Neurotrophin signaling pathway
Regulation of actin cytoskeleton
Insulin signaling pathway
GnRH signaling pathway
Estrogen signaling pathway
Prolactin signaling pathway
Alcoholism
Hepatitis C
Pathways in cancer
Proteoglycans in cancer
MicroRNAs in cancer
Renal cell carcinoma
Endometrial cancer
Glioma
Prostate cancer
Chronic myeloid leukemia
Acute myeloid leukemia
Non-small cell lung cancer
Brite
KEGG Orthology (KO) [BR:pon00001]
 Environmental Information Processing
  Signal transduction
   04014 Ras signaling pathway
    100458733 (SOS1)
   04010 MAPK signaling pathway
    100458733 (SOS1)
   04012 ErbB signaling pathway
    100458733 (SOS1)
   04630 Jak-STAT signaling pathway
    100458733 (SOS1)
   04068 FoxO signaling pathway
    100458733 (SOS1)
   04151 PI3K-Akt signaling pathway
    100458733 (SOS1)
 Cellular Processes
  Cell motility
   04810 Regulation of actin cytoskeleton
    100458733 (SOS1)
  Cellular commiunity
   04510 Focal adhesion
    100458733 (SOS1)
   04540 Gap junction
    100458733 (SOS1)
 Organismal Systems
  Immune system
   04650 Natural killer cell mediated cytotoxicity
    100458733 (SOS1)
   04660 T cell receptor signaling pathway
    100458733 (SOS1)
   04662 B cell receptor signaling pathway
    100458733 (SOS1)
   04664 Fc epsilon RI signaling pathway
    100458733 (SOS1)
   04062 Chemokine signaling pathway
    100458733 (SOS1)
  Endocrine system
   04910 Insulin signaling pathway
    100458733 (SOS1)
   04912 GnRH signaling pathway
    100458733 (SOS1)
   04915 Estrogen signaling pathway
    100458733 (SOS1)
   04917 Prolactin signaling pathway
    100458733 (SOS1)
  Nervous system
   04722 Neurotrophin signaling pathway
    100458733 (SOS1)
  Development
   04320 Dorso-ventral axis formation
    100458733 (SOS1)
 Human Diseases
  Cancers
   05200 Pathways in cancer
    100458733 (SOS1)
   05206 MicroRNAs in cancer
    100458733 (SOS1)
   05205 Proteoglycans in cancer
    100458733 (SOS1)
   05214 Glioma
    100458733 (SOS1)
   05221 Acute myeloid leukemia
    100458733 (SOS1)
   05220 Chronic myeloid leukemia
    100458733 (SOS1)
   05211 Renal cell carcinoma
    100458733 (SOS1)
   05215 Prostate cancer
    100458733 (SOS1)
   05213 Endometrial cancer
    100458733 (SOS1)
   05223 Non-small cell lung cancer
    100458733 (SOS1)
  Substance dependence
   05034 Alcoholism
    100458733 (SOS1)
  Infectious diseases
   05160 Hepatitis C
    100458733 (SOS1)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif Motif
Other DBs
NCBI-GI: 
NCBI-GeneID: 
Position
2A
AA seq 1396 aa AA seqDB search
MQAQQLPYEFFSEENAPKWRGLLVPALKKVRSTRDPASRPQPPSAGAGPALGKGWGGGAR
AGPSFFPVSPRLQKDGAHGEAPLIRLALGVDIHRVCGKAAGSRGEFIQIIQPLRACNGRG
VGGLCDARSWCPDRERVQKSFPHPIDKWAIADAQSAIEKRKRRNPLSLPVEKIHPLLKEV
LGYKIDHQVSVYIVAVLEYISADILKLVGNYVRNIRHYEITKQDIKVAMCADKVLMDMFH
QDVEDINVLSLTDEEPSTSGEQTYYDLVKAFMAEIRQYIRELNLIIKVFREPFVSNSKLF
SANDVENIFSRIVDIHELSVKLLGHIEDTVEMTDEGSPHPLVGSCFEDLAEELAFDPYES
YARDILRPGFHDRFLSQLSKPGAALYLQSIGEGFKEAVQYVLPRLLLAPVYHCLHYFELL
KQLEEKSEDQEDKECLKQAITALLNVQSGMEKICSKSLAKRRLSESACRFYSQQMKGKQL
AIKKMNEIQKNIDGWEGKDIGQCCNEFIMEGTLTRVGAKHERHIFLFDGLMICCKSNHGQ
PRLPGASNAEYRLKEKFFMRKVQINDKDDTNEYKHAFEIILKDENSVIFSAKSAEEKNNW
MAALISLQYRSTLERMLDVTMLQEEKEEQMRLPSADVYRFAEPDSEENIIFEENMQPKAG
IPIIKAGTVIKLIERLTYHMYADPNFVRTFLTTYRSFCKPQELLSLIIERFEIPEPEPTE
ADRIAIENGDQPLSAELKRFRKEYIQPVQLRVLNVCRHWVEHHFYDFERDAYLLQRMEEF
IGTVRGKAMKKWVESITKIIQRKKIARDNGPGHNITFQSSPPTVEWHISRPGHIETFDLL
TLHPIEIARQLTLLESDLYRAVQPSELVGSVWTKEDKEINSPNLLKMIRHTTNLTLWFEK
CIVETENLEERVAVVSRIIEILQVFQELNNFNGVLEVVSAMNSSPVYRLDHTFEQIPSRQ
KKILEEAHELSEDHYKKYLAKLRSINPPCVPFFGIYLTNILKTEEGNPEVLKRHGKELIN
FSKRRKVAEITGEIQQYQNQPYCLRVESDIKRFFENLNPMGNSMEKEFTDYLFNKSLEIE
PRNPKPLPRFPKKYSYPLKSPGVRPSNPRPGTMRHPTPLQQEPRKISYSRIPESETESTA
SAPNSPRTPLTPPPASGASSTTDVCSVFDSDHSSPFHSSNDTVFIQVTLPHGPRSASVSS
ISLTKGTDEVPVPPPVPPRRRPESAPAESSPSKIMSKHLDSPPAIPPRQPTSKAYSPRYS
ISDRTSVSDPPESPPLLPPREPVRTPDVFSSSPLHLQPPPLGKKXDHGNAFFPNSPSPFT
PPPPQTPSPHGTRRHLPSPPLTQEVDLHSIAGPPVPPRQSTSQHIPKLPPKTYKREHTHP
SMHRDGPPLLENAHSS
NT seq 4191 nt NT seq  +upstreamnt  +downstreamnt
atgcaggcgcagcagctgccctacgagtttttcagcgaagagaacgcgcccaagtggcgg
ggactgctggtgcctgcgctgaaaaaggtgaggagcacgcgggaccccgcttcccggccg
cagccccccagcgcgggcgccgggccggcgctggggaagggctggggaggcggggcgcgc
gcagggccgtctttcttcccggtctcgccgcgtctccaaaaggacggcgcacacggagag
gcccccctcatacggctggctctcggtgttgacatccaccgggtgtgtgggaaggccgca
gggagccggggggagtttatccagataatccaacccctgagagcttgtaatggaaggggt
gtaggaggtctctgtgatgctagaagctggtgtccggatagggaacgtgttcaaaaaagt
ttccctcatccaattgataaatgggcaatagctgatgcccaatcagctattgaaaagagg
aagcgaagaaaccctttatctctcccagtagaaaaaattcatcctttattaaaggaggtc
ctaggttataaaattgaccaccaggtttctgtttacatagtagcagtcttagaatacatt
tctgcagacattttaaagctggttgggaattacgtaagaaatatacggcattatgaaatt
acaaaacaagatattaaagtggcaatgtgtgctgacaaggtattgatggatatgtttcat
caagatgtagaagatattaatgtattatctttaactgatgaagagccttccacctcagga
gaacaaacttactatgatttggtaaaagcatttatggcagaaattcgacaatatataagg
gaactaaatctaattataaaagtttttagagagccctttgtctccaattcaaaattgttt
tcagctaatgatgtagaaaatatatttagtcgcatagtagatatacatgaacttagtgta
aagttactgggccatatagaagatacagtagaaatgacagatgaaggcagtccccatcca
ctagtaggaagctgctttgaagacttagcagaggaactggcatttgatccatatgaatcg
tatgctcgagatattttgcgacctggttttcatgatcgtttccttagtcagttatcaaag
cctggggcagcactttatttgcagtcaataggcgaaggtttcaaagaagctgttcaatac
gttttacccaggctgcttctggcccctgtttaccactgtctccattactttgaacttttg
aagcagttagaagaaaaaagtgaagatcaagaagacaaggaatgtttaaaacaagcaata
acagctttgcttaatgttcagagtggtatggaaaaaatatgttctaaaagtcttgcaaaa
cgaagactgagtgaatctgcatgtcggttttatagtcagcaaatgaaggggaaacaacta
gcaatcaagaaaatgaacgagattcagaagaatattgatggttgggagggaaaagacatt
ggacagtgttgcaatgaatttataatggaaggaactcttacacgtgtaggagccaaacat
gagagacacatatttctctttgatggcttaatgatttgctgtaaatcaaatcatgggcag
ccaagacttcctggtgctagcaatgcagaatatcgtcttaaagaaaagttttttatgcga
aaggtacaaattaatgataaagatgacaccaatgaatacaaacatgcttttgaaataatt
ttaaaagatgaaaatagtgttatattttctgccaagtcagctgaagagaaaaacaattgg
atggcagcattgatatctttacagtaccggagtacactggaaaggatgcttgatgtaaca
atgctacaggaagagaaagaggagcagatgaggctgcctagtgccgatgtttatagattt
gcagagcctgactctgaagagaatattatatttgaagagaacatgcagcccaaggctgga
attccaattatcaaagcaggaactgttattaaacttatagagaggcttacgtaccatatg
tacgcagatcccaattttgttcggacatttcttacaacatacagatccttttgcaaacct
caagaactactgagtcttataatagaaaggtttgaaattccagagcctgagccaacagaa
gctgatcgcatagctatagagaatggagatcaacccttgagtgcagaactaaaaagattt
agaaaagaatatatacagcctgtgcaactgcgagtattaaatgtatgtcggcactgggta
gagcaccacttctatgattttgaaagagatgcatatcttttgcaacgaatggaagaattt
attggaacagtaagaggtaaagcaatgaaaaaatgggttgaatccatcactaaaataatc
caaaggaaaaaaattgcaagagacaatggaccaggtcataatattacatttcagagttca
cctcccacagttgagtggcatataagcagacctgggcacatagagacttttgacctgctc
accttacacccaatagaaattgctcgacaactcactttacttgaatcagatctataccga
gctgtacagccatcagaattagttggaagtgtgtggacaaaagaagacaaagaaattaac
tctcctaatcttctgaaaatgattcgacataccaccaacctcactctgtggtttgagaaa
tgtattgtagaaactgaaaatttagaagaaagagtagctgtggtgagtcgaataattgag
attctacaagtctttcaagagttgaacaactttaatggtgtccttgaggtcgtcagtgct
atgaattcatcacctgtttacagactagaccacacatttgagcaaataccaagtcgccag
aagaaaattttagaagaagctcatgaattgagtgaagatcactataagaaatatttggca
aaactcaggtctattaatccaccatgtgtgcctttctttggaatttatctcactaatatc
ttgaaaacagaagaaggcaaccctgaggtcctaaaaagacatgggaaagagcttataaac
tttagcaaaaggaggaaagtagcagaaataacaggagagatccagcagtaccaaaatcag
ccttactgtttacgagtagaatcagatatcaaaaggttctttgaaaacttgaatccgatg
ggaaatagcatggagaaagaatttacagattatcttttcaacaaatccctagaaatagaa
ccacgaaaccctaagcctctcccaagatttccaaaaaaatatagctatcccctaaaatct
cctggtgttcgtccatcaaacccaagaccaggtaccatgaggcatcccacacctctgcag
caggagccaaggaaaattagttatagtaggatccctgaaagtgaaacagaaagtacagca
tctgcaccaaattctccaagaacaccgttaacacctccgcctgcttctggtgcttccagt
accacagatgtttgcagtgtatttgattccgatcattcgagcccttttcactcaagcaat
gataccgtctttatccaagttactctgccccatggcccaagatctgcttctgtatcatct
ataagtttaaccaaaggcactgatgaagtgcctgtccctcctcctgttcctccacgaaga
cgaccagaatctgccccagcagaatcttcaccatctaagattatgtctaagcatttggac
agtcccccagccattcctcctaggcaacccacatcaaaagcctattcaccacgatattca
atatcagaccggacctctgtctcagaccctcctgaaagccctcccttattaccaccacga
gaacctgtgaggacacctgatgttttctcaagctcaccactacatctccaacctccccct
ttgggcaaaaaangtgaccatggcaatgccttcttcccaaacagcccttccccttttaca
ccacctcctcctcaaacaccttctcctcacggcacaagaaggcatctgccatcaccacca
ttgacacaagaagtggaccttcattccattgctgggccgcctgttcctccacgacaaagc
acttctcaacatatccctaaactccctccaaaaacttacaaaagggagcacacacaccca
tccatgcacagagatggaccaccactgttggagaatgcccattcttcctga

DBGET integrated database retrieval system