KEGG   Pongo abelii (Sumatran orangutan): 100459152Help
Entry
100459152         CDS       T01416                                 

Gene name
GCK
Definition
glucokinase (hexokinase 4)
Orthology
K12407  
glucokinase [EC:2.7.1.2]
Organism
pon  Pongo abelii (Sumatran orangutan)
Pathway
Glycolysis / Gluconeogenesis
Galactose metabolism
Starch and sucrose metabolism
Amino sugar and nucleotide sugar metabolism
Butirosin and neomycin biosynthesis
Metabolic pathways
Carbon metabolism
Insulin signaling pathway
Insulin secretion
Prolactin signaling pathway
Type II diabetes mellitus
Maturity onset diabetes of the young
Module
Glycolysis (Embden-Meyerhof pathway), glucose => pyruvate
Nucleotide sugar biosynthesis, glucose => UDP-glucose
Brite
KEGG Orthology (KO) [BR:pon00001]
 Metabolism
  Overview
   01200 Carbon metabolism
    100459152 (GCK)
  Carbohydrate metabolism
   00010 Glycolysis / Gluconeogenesis
    100459152 (GCK)
   00052 Galactose metabolism
    100459152 (GCK)
   00500 Starch and sucrose metabolism
    100459152 (GCK)
   00520 Amino sugar and nucleotide sugar metabolism
    100459152 (GCK)
  Biosynthesis of other secondary metabolites
   00524 Butirosin and neomycin biosynthesis
    100459152 (GCK)
 Organismal Systems
  Endocrine system
   04911 Insulin secretion
    100459152 (GCK)
   04910 Insulin signaling pathway
    100459152 (GCK)
   04917 Prolactin signaling pathway
    100459152 (GCK)
 Human Diseases
  Endocrine and metabolic diseases
   04930 Type II diabetes mellitus
    100459152 (GCK)
   04950 Maturity onset diabetes of the young
    100459152 (GCK)
Enzymes [BR:pon01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.1  Phosphotransferases with an alcohol group as acceptor
    2.7.1.2  glucokinase
     100459152 (GCK)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif Motif
Other DBs
NCBI-GI: 
NCBI-GeneID: 
Ensembl: 
UniProt: 
Position
7
AA seq 466 aa AA seqDB search
MAMDVTRSQVQTALTLVEQILAEFQLQEEDLKKVMRRMQKEMDRGLRLETHEEASVKMLP
TYVRSTPEGSEVGDFLSLDLGGTNFRVMLVKVGEGEEGQWSVKTKHQMYSIPEDAMTGTA
EMLFDYISECISDFLDKHQMKHKKLPLGFTFSFPVRHEDIDKGILLNWTKGFKASGAEGN
NVVGLLRDAIKRRGDFEMDVVAMVNDTVATMISCYYEDHQCEVGMIVGTGCNACYMEEME
NVELVEGDEGRMCVNTEWGAFGDSGELDEFLLEYDRLVDESSANPGQQLYEKLIGGKYMG
ELVRLVLLRLVDENLLFHGEASEQLRTRGAFETRFVSQVESDTGDRKQIYNILSTLGLRP
STTDCDIVRRACESVSTRAAHMCSAGLAGVINRMRESRSEDVMRITVGVDGSVYKLHPSF
KERFHASVRRLTPSCEITFIESEEGSGRGAALVSAVACKKACMLGQ
NT seq 1401 nt NT seq  +upstreamnt  +downstreamnt
atggcgatggatgtcacaaggagccaggtccagacagccttgactctggtagagcagatc
ctggcagagttccagctgcaggaggaggacctgaagaaggtgatgagacggatgcagaag
gagatggaccgtggcctgaggctggagacccatgaagaggccagtgtgaagatgttgccc
acctacgtgcgctccaccccagaaggctcagaagtcggggacttcctctccctggacctg
ggtggcactaacttcagggtgatgctggtgaaggtgggagaaggtgaggaggggcagtgg
agcgtgaagaccaaacaccagatgtactccatccccgaggacgccatgaccggcactgct
gagatgctcttcgactacatctccgagtgcatctccgacttcctggacaagcatcagatg
aagcacaagaagctgcccctgggcttcaccttctcctttcctgtgaggcacgaagacatc
gataagggcatccttctcaactggaccaagggcttcaaggcctcaggagcagaagggaac
aatgtcgtggggcttctgcgagacgccatcaaacggagaggggactttgaaatggatgtg
gtggcaatggtgaatgacacggtggccacgatgatctcctgctactatgaagaccatcag
tgcgaggtcggcatgattgtgggtacaggctgcaatgcctgctacatggaggagatggag
aatgtggagctggtggagggggacgagggccgcatgtgcgtcaacactgagtggggcgcc
ttcggggactccggcgagctggacgagttcctgctggagtatgaccgcctggtggacgag
agctctgcaaaccccggtcagcagctgtatgagaagctcataggtggcaagtacatgggc
gagctggtgcggctcgtgctgctcagactagtggacgaaaacctgctcttccacggggag
gcctccgagcagctgcgcacacgcggagccttcgagacgcgcttcgtgtcgcaggtggag
agcgacacgggcgaccgcaagcagatctacaacatcctgagcacgctggggctgcgaccc
tcgaccaccgactgtgacatcgtgcgccgcgcctgcgagagcgtgtctacgcgcgctgcg
cacatgtgctcggcggggctggcgggtgtcatcaatcgcatgcgcgagagccgcagcgag
gacgtaatgcgcatcactgtgggcgtggatggctccgtgtacaagctgcaccccagcttc
aaggagcggttccacgctagcgtgcgcaggctgacgcccagctgcgagatcaccttcatc
gagtcggaggagggcagtggccggggcgcagccctggtctcggcggtggcctgtaagaag
gcctgcatgctgggccagtga

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