KEGG   Pongo abelii (Sumatran orangutan): 100459236Help
Entry
100459236         CDS       T01416                                 

Gene name
TGFBR2
Definition
transforming growth factor, beta receptor II (70/80kDa)
Orthology
K04388  
TGF-beta receptor type-2 [EC:2.7.11.30]
Organism
pon  Pongo abelii (Sumatran orangutan)
Pathway
MAPK signaling pathway
Cytokine-cytokine receptor interaction
FoxO signaling pathway
Endocytosis
TGF-beta signaling pathway
Osteoclast differentiation
Hippo signaling pathway
Adherens junction
Chagas disease (American trypanosomiasis)
HTLV-I infection
Pathways in cancer
Transcriptional misregulation in cancer
Colorectal cancer
Pancreatic cancer
Chronic myeloid leukemia
Brite
KEGG Orthology (KO) [BR:pon00001]
 Environmental Information Processing
  Signal transduction
   04010 MAPK signaling pathway
    100459236 (TGFBR2)
   04350 TGF-beta signaling pathway
    100459236 (TGFBR2)
   04390 Hippo signaling pathway
    100459236 (TGFBR2)
   04068 FoxO signaling pathway
    100459236 (TGFBR2)
  Signaling molecules and interaction
   04060 Cytokine-cytokine receptor interaction
    100459236 (TGFBR2)
 Cellular Processes
  Transport and catabolism
   04144 Endocytosis
    100459236 (TGFBR2)
  Cellular commiunity
   04520 Adherens junction
    100459236 (TGFBR2)
 Organismal Systems
  Development
   04380 Osteoclast differentiation
    100459236 (TGFBR2)
 Human Diseases
  Cancers
   05200 Pathways in cancer
    100459236 (TGFBR2)
   05202 Transcriptional misregulation in cancers
    100459236 (TGFBR2)
   05210 Colorectal cancer
    100459236 (TGFBR2)
   05212 Pancreatic cancer
    100459236 (TGFBR2)
   05220 Chronic myeloid leukemia
    100459236 (TGFBR2)
  Infectious diseases
   05166 HTLV-I infection
    100459236 (TGFBR2)
   05142 Chagas disease (American trypanosomiasis)
    100459236 (TGFBR2)
Enzymes [BR:pon01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.30  receptor protein serine/threonine kinase
     100459236 (TGFBR2)
Protein kinases [BR:pon01001]
 Serine/threonine protein kinases: TKL group
  TGFBR2 family [OT]
   100459236 (TGFBR2)
Enzyme-linked receptors [BR:pon01020]
 Receptor serine/threonine kinases
  Type II TGF-beta receptor
   100459236 (TGFBR2)
Cytokine receptors [BR:pon04050]
 TGF-beta receptors
  Type II TGF-beta receptor
   100459236 (TGFBR2)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif Motif
Other DBs
NCBI-GI: 
NCBI-GeneID: 
Ensembl: 
UniProt: 
Position
3
AA seq 592 aa AA seqDB search
MGRGLLRGLWPLHIVLWTRIASTIPPHVQKSDVEMEAQKDEIICPSCNRTAHPLRHINND
MMVTDNNGAVKFPQLCKFCDVRFSTCDNQKSCMSNCSITSICEKPQEVCVAVWRKNDENI
TLETVCHDPKLPYHDFILEDAASPKCIMKEKKKPGETFFMCSCSSDECNDNIIFSEEYNT
SNPDLLLVIFQVTGISLLPPLGVAISVIIIFYCYRVNRQQKLSSSWETGKTRKLMEFSEH
CAIILEDDRSDISSTCANNINHNTELLPIELDTLVGKGRFAEVYKAKLKQNTSEQFETVA
VKIFPYEEYASWKTEKDIFSDINLKHENILQFLTAEERKTELGKQYWLITAFHAKGNLQE
YLTRHVISWEDLRKLGSSLARGIAHLHSDHTPCGRPKMPIVHRDLKSSNILVKNDLTCCL
CDFGLSLRLDPTLSVDDLANSGQVGTARYMAPEVLESRMNLENVESFKQTDVYSMALVLW
EMTSRCNAVGEVKDYEPPFGSKVREHPCVESMKDNVLRDRGRPEIPSFWLNHQGIQMVCE
TLTECWDHDPEARLTAQCVAERFSELEHLDRLSGRSCSEEKIPEDGSLNTTK
NT seq 1779 nt NT seq  +upstreamnt  +downstreamnt
atgggtcgggggctgctcaggggcctgtggccgctgcacatcgtcctgtggacgcgtatc
gccagcacgatcccaccgcacgttcagaagtcggatgtggaaatggaggcccagaaagat
gaaatcatctgccccagctgtaataggactgcccatccactgagacatattaataatgac
atgatggtcactgacaacaatggtgcagtcaagtttccacaactgtgtaaattttgtgat
gtgagattttccacctgtgacaaccagaaatcctgcatgagcaactgcagcatcacctcc
atctgtgagaagccacaggaagtctgtgtggctgtatggagaaagaatgatgagaacata
acactagagacagtttgccatgaccccaagctgccctaccatgactttattctggaagat
gctgcttctccaaagtgcattatgaaggaaaaaaaaaagcctggtgagactttcttcatg
tgttcctgtagctctgatgagtgcaatgacaacatcatcttctcagaagaatataacacc
agcaatcctgacttgttgctagtcatatttcaagtgacaggcatcagcctcctgccacca
ctgggagttgccatatctgtcatcatcatcttctactgctaccgcgttaaccggcagcag
aagctgagttcatcctgggaaaccggcaagacgcggaagctcatggagttcagtgagcac
tgtgccatcatcctggaagacgaccgctctgacatcagctccacgtgcgccaacaacatc
aaccacaacacagagctgctgcccattgagctggacacgctggtggggaaaggtcgcttt
gctgaggtctataaggccaagctgaagcagaacacttcagagcagtttgagacagtggca
gtcaagatctttccctatgaggagtatgcctcttggaagacagagaaggacatcttctca
gacatcaacctgaagcatgagaacatactccagttcctgacggctgaggagcggaagacg
gagttggggaaacagtactggctgatcaccgctttccacgccaagggcaacctacaggag
tacctgacacggcatgtcatcagctgggaggacctgcgcaagctgggcagctccctcgcc
cgggggattgctcacctccacagtgatcacactccatgtgggaggcccaagatgcccatc
gtgcacagggacctcaagagctccaatatcctcgtgaagaacgacctaacctgctgcctg
tgtgactttgggctttccctgcgtctggaccctactctgtctgtggatgacctggctaac
agtgggcaggtgggaactgcaagatacatggctccagaagtcctagaatccaggatgaat
ttggagaatgttgagtccttcaagcagaccgatgtctactccatggctctggtgctctgg
gaaatgacatctcgttgtaatgcagtgggagaagtaaaagattatgagcctccatttggt
tccaaggtgcgggagcacccctgtgtggaaagcatgaaggacaacgtgttgagagatcga
gggcgaccagaaattcccagcttctggctcaaccaccagggcatccagatggtgtgtgag
acgttgactgagtgctgggaccacgacccagaggcccgtctcacagcccagtgtgtggca
gaacgcttcagtgagctggagcatctggacaggctctcggggaggagctgctcggaggag
aagattcctgaagacggctccctaaacactaccaagtag

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