KEGG   Pichia pastoris: PAS_chr1-4_0160Help
Entry
PAS_chr1-4_0160   CDS       T01092                                 

Definition
Multifunctional enzyme HIS4
Orthology
K14152  
phosphoribosyl-ATP pyrophosphohydrolase / phosphoribosyl-AMP cyclohydrolase / histidinol dehydrogenase [EC:3.6.1.31 3.5.4.19 1.1.1.23]
Organism
ppa  Pichia pastoris
Pathway
Histidine metabolism
Metabolic pathways
Biosynthesis of secondary metabolites
Biosynthesis of amino acids
Module
Histidine biosynthesis, PRPP => histidine
Brite
KEGG Orthology (KO) [BR:ppa00001]
 Metabolism
  Overview
   01230 Biosynthesis of amino acids
    PAS_chr1-4_0160
  Amino acid metabolism
   00340 Histidine metabolism
    PAS_chr1-4_0160
Enzymes [BR:ppa01000]
 1. Oxidoreductases
  1.1  Acting on the CH-OH group of donors
   1.1.1  With NAD+ or NADP+ as acceptor
    1.1.1.23  histidinol dehydrogenase
     PAS_chr1-4_0160
 3. Hydrolases
  3.5  Acting on carbon-nitrogen bonds, other than peptide bonds
   3.5.4  In cyclic amidines
    3.5.4.19  phosphoribosyl-AMP cyclohydrolase
     PAS_chr1-4_0160
  3.6  Acting on acid anhydrides
   3.6.1  In phosphorus-containing anhydrides
    3.6.1.31  phosphoribosyl-ATP diphosphatase
     PAS_chr1-4_0160
BRITE hierarchy
SSDB OrthologParalogGene clusterGFIT
Motif Motif
Other DBs
NCBI-GI: 
NCBI-GeneID: 
UniProt: 
Position
1:1701657..1704188
Genome map
AA seq 843 aa AA seqDB search
MTFPLLPAYASVAEFDNSLSLVGKAVFPYAADQLHNLIKFTQSTELQVNVQVESSVTEDQ
FEELIDNLLKLYNNGINEVILDLDLAERVVQRIPGARVIYRTLVDKVASLPANASIAVPF
SSPLGDLKSFTNGGSRTVYAFSETAKLVDVTSTVASGIIPIIDARQLTTEYELSEDVKKF
PVSEILLASLTTDRPDGLFTTLVADSSNYSLGLVYSSKKSIPEAIRTQTGVYQSRRHGLW
YKGATSGATQKLLGIELDCDGDCLKFVVEQTGVGFCHLERTSCFGQSKGLRAMEATLWDR
KSNAPEGSYTKRLFDDEVLLNAKIREEADELAEAKSKEDIAWECADLFYFALVRCAKYGV
TLDEVERNLDMKSLKVTRRKGDAKPGYTKEQPKEESKPKEVPSEGRIELCKIDVSKASSQ
EIEDALRRPIQKTEQIMELVKPIVDNVRQNGDKALLELTAKFDGVALKTPVLEAPFPEEL
MQLPDNVKRAIDLSIDNVRKFHEAQLTETLQVETCPGVVCSRFARPIEKVGLYIPGGTAI
LPSTSLMLGVPAKVAGRKEIVFASPPKKDGTLTPEVIYVAHKVGAKCIVLAGGAQAVAAM
AYGTETVPKCDKIFGPGNQFVTAAKMMVQNDTSALCSIDMPAGPSEVLVIADKYADPDFV
ASDLLSQAEHGIDSQVILLAVDMTDKELARIEDAVHNQAVQLPRVEIVRKCIAHSTTLSV
ATYEQALEMSNQYAPEHLILQIENASSYVDQVQHAGSVFVGAYSPESCGDYSSGTNHTLP
TYGYARQYSGVNTATFQKFITSQDVTPEGLKHIGQAVMDLAAVEGLDAHRNAVKVRMEKL
GLI
NT seq 2532 nt NT seq  +upstreamnt  +downstreamnt
atgacatttcccttgctacctgcatacgcaagtgttgcagagtttgataattccttgagt
ttggtaggaaaagccgtgtttccctatgctgctgaccagctgcacaacctgatcaagttc
actcaatcgactgagcttcaagttaatgtgcaagttgagtcatccgttacagaggaccaa
tttgaggagctgatcgacaacttgctcaagttgtacaataatggtatcaatgaagtgatt
ttggacctagatttggcagaaagagttgtccaaaggatcccaggcgctagggttatctat
aggaccctggttgataaagttgcatccttgcccgctaatgctagtatcgctgtgcctttt
tcttctccactgggcgatttgaaaagtttcactaatggcggtagtagaactgtttatgct
ttttctgagaccgcaaagttggtagatgtgacttccactgttgcttctggtataatcccc
attattgatgctcggcaattgactactgaatacgaactttctgaagatgtcaaaaagttc
cctgtcagtgaaattttgttggcgtctttgactactgaccgccccgatggtctattcact
actttggtggctgactcttctaattactcgttgggcctggtgtactcgtccaaaaagtct
attccggaggctataaggacacaaactggagtctaccaatctcgtcgtcacggtttgtgg
tataaaggtgctacatctggagcaactcaaaagttgctgggtatcgaattggattgtgat
ggagactgcttgaaatttgtggttgaacaaacaggtgttggtttctgtcacttggaacgc
acttcctgttttggccaatcaaagggtcttagagccatggaagccaccttgtgggatcgt
aagagcaatgctccagaaggttcttataccaaacggttatttgacgacgaagttttgttg
aacgctaaaattagggaggaagctgatgaacttgcagaagctaaatccaaggaagatata
gcctgggaatgtgctgacttattttattttgcattagttagatgtgccaagtacggtgtg
acgttggacgaggtggagagaaacctggatatgaagtccctaaaggtcactagaaggaaa
ggagatgccaagccaggatacaccaaggaacaacctaaagaagaatccaaacctaaagaa
gtcccttctgaaggtcgtattgaattgtgcaaaattgacgtttctaaggcctcctcacaa
gaaattgaagatgcccttcgtcgtcctatccagaaaacggaacagattatggaattagtc
aaaccaattgtcgacaatgttcgtcaaaatggtgacaaagcccttttagaactaactgcc
aagtttgatggagtcgctttgaagacacctgtgttagaagctcctttcccagaggaactt
atgcaattgccagataacgttaagagagccattgatctctctatagataacgtcaggaaa
ttccatgaagctcaactaacggagacgttgcaagttgagacttgccctggtgtagtctgc
tctcgttttgcaagacctattgagaaagttggcctctatattcctggtggaaccgcaatt
ctgccttccacttccctgatgctgggtgttcctgccaaagttgctggtcgcaaagaaatt
gtttttgcatctccacctaagaaggatggtacccttaccccagaagtcatctacgttgcc
cacaaggttggtgctaagtgtatcgtgctagcaggaggcgcccaggcagtagctgctatg
gcttacggaacagaaactgttcctaagtgtgacaaaatatttggtccaggaaaccagttc
gttactgctgccaagatgatggttcaaaatgacacatcagccctgtgtagtattgacatg
cctgctgggccttctgaagttctagttattgctgataaatacgctgatccagatttcgtt
gcctcagaccttctgtctcaagctgaacatggtattgattcccaggtgattctgttggct
gtcgatatgacagacaaggagcttgccagaattgaagatgctgttcacaaccaagctgtg
cagttgccaagggttgaaattgtacgcaagtgtattgcacactctacaaccctatcggtt
gcaacctacgagcaggctttggaaatgtccaatcagtacgctcctgaacacttgatcctg
caaatcgagaatgcttcttcttatgttgatcaagtacaacacgctggatctgtgtttgtt
ggtgcctactctccagagagttgtggagattactcctccggtaccaaccacactttgcca
acgtacggatatgcccgtcaatacagcggagttaacactgcaaccttccagaagttcatc
acttcacaagacgtaactcctgagggactgaaacatattggccaagcagtgatggatctg
gctgctgttgaaggtctagatgctcaccgcaatgctgttaaggttcgtatggagaaactg
ggacttatttaa

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