KEGG   Propionibacterium propionicum: HMPREF9154_0442Help
Entry
HMPREF9154_0442   CDS       T02180                                 

Gene name
hemD
Definition
uroporphyrinogen-III synthase (EC:4.2.1.75)
Orthology
K13542  
uroporphyrinogen III methyltransferase / synthase [EC:2.1.1.107 4.2.1.75]
Organism
ppc  Propionibacterium propionicum
Pathway
Porphyrin and chlorophyll metabolism
Metabolic pathways
Biosynthesis of secondary metabolites
Brite
KEGG Orthology (KO) [BR:ppc00001]
 Metabolism
  Metabolism of cofactors and vitamins
   00860 Porphyrin and chlorophyll metabolism
    HMPREF9154_0442 (hemD)
Enzymes [BR:ppc01000]
 2. Transferases
  2.1  Transferring one-carbon groups
   2.1.1  Methyltransferases
    2.1.1.107  uroporphyrinogen-III C-methyltransferase
     HMPREF9154_0442 (hemD)
 4. Lyases
  4.2  Carbon-oxygen lyases
   4.2.1  Hydro-lyases
    4.2.1.75  uroporphyrinogen-III synthase
     HMPREF9154_0442 (hemD)
BRITE hierarchy
SSDB OrthologParalogGene clusterGFIT
Motif Motif
Other DBs
NCBI-GI: 
NCBI-GeneID: 
UniProt: 
Position
465726..467306
Genome map
AA seq 526 aa AA seqDB search
MIHTEEPEPTGTPMGVVTFVGFGPGDPGLITWAGSREVTGADLLVVDSPTMVEELASVGI
EPLGEVVQVEADEVAQLVAAVSDGRSVVRLVEGDFFTEAGHVDVLRRLLEGKRIRTHLIP
GITTWNAALTYGAVAPTSVMGFCDASVELPGKDGWPKRGTVVIRATDESISRVVAEARAV
YGETAEVLELTGLGGTSQKTRLTTWGDLGSEPCGGPRFLLFGPGIGDVARARVDWFESKP
LFDWSVLVPRTKDEVTELTDHLARFGASTEVVATMSIEPPRTEQAMEKAVRGIVDGRFLW
VVFTSQHAVRAIVDRLAEYGLDSRALSGIQLAAVGRGTVEALGRVGLTPDLTPSEGDTAH
DLALEFPAYDDLIDPMARVLVPTADVSVADLVQGLTNLGWEVEEVTAYRTVRAAPPPAEI
RDRIKTGLFDAVVFTSSSAVRNMIGIAGKPHTTSIIAAIGQATASTCEMHGLRVDVVADS
PNFESVAVGLARFADERRADRLAQGLPDTKPSQRRRRRRRDPNRGA
NT seq 1581 nt NT seq  +upstreamnt  +downstreamnt
gtgatccacaccgaggaaccggaaccgaccgggacgcccatgggggtggtcacgtttgtc
ggtttcggccctggggaccccgggctcatcacgtgggcgggcagccgcgaggtaacaggg
gctgatcttctcgtggtcgactccccgaccatggtggaagaactcgcctcggtcggtatc
gaacccttgggcgaggtcgtccaggtcgaggccgacgaggtggcccagttggtcgctgcc
gtgagcgacgggcgttccgtagtgaggctcgtcgagggggacttcttcaccgaggccggg
cacgtggacgttctgcggcggctcctggagggcaagcgcatccgcacccacctgattccc
ggaatcacgacctggaacgcggccctgacctacggggccgtcgctcccacttctgtgatg
ggtttctgcgacgcctccgtcgagctgcccggcaaggatggctggcccaagcgcggcacc
gtggtgatccgtgccaccgacgagtcgatttcccgggtggtcgctgaggcccgagccgtc
tatggggagaccgccgaggtgctggagttgaccgggctcggcggcacctcccagaaaacc
cgcctgaccacgtggggtgatctcggatccgaaccctgcggtgggccgcggttcctgctg
ttcggtcccggcatcggtgacgtcgcccgcgcccgcgtcgactggtttgagtccaaaccg
ctgttcgactggagcgttctcgtgccgcgcaccaaggacgaagtcacggagctgaccgat
cacctggcccgtttcggggcatccaccgaggtggtggcgacgatgtccatcgaaccgccc
cgcacggaacaggccatggagaaggcggttcgcggcatcgtcgacgggcgtttcctgtgg
gtggttttcacctcccaacacgcggtgcgggccatcgtcgacagactcgcggagtatggc
ctggattcgcgtgccctctccggtatccaactggcggcggtcggccgcggcacggtggag
gccctcggccgggtcggcctcacccccgacctgacaccgtcggagggcgacaccgcccac
gacctggcgttggagttccccgcctacgacgacctgatcgaccccatggcgcgggtgctc
gtgccgaccgccgacgtgtcggtggcggatctggtgcagggcctgacgaatctcggctgg
gaggtcgaggaggtcaccgcctaccgcacggtgcgggccgccccgccgcccgccgagatc
agggaccgcatcaagaccgggttgttcgacgcggtggtgttcacctcgtcgtcggcggtg
cgcaacatgatcggcatcgcgggcaaaccccacacgacctccatcatcgcggccatcggg
caggcaaccgcctcgacctgcgagatgcacggcctcagggtggatgtggtggcggactcc
ccgaacttcgaatcggtggccgtcggtctggcgcgtttcgcggacgaacgccgcgccgac
cggctggcgcaggggctgccggacacgaaaccctcccagcggcgacgccggcgccgcagg
gaccccaaccggggggcttga

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