KEGG   Pan paniscus (bonobo): 100968237Help
Entry
100968237         CDS       T02283                                 

Gene name
PRKACA
Definition
protein kinase, cAMP-dependent, catalytic, alpha
Orthology
K04345  
protein kinase A [EC:2.7.11.11]
Organism
pps  Pan paniscus (bonobo)
Pathway
MAPK signaling pathway
Ras signaling pathway
Calcium signaling pathway
cAMP signaling pathway
Chemokine signaling pathway
Oocyte meiosis
Apoptosis
Adrenergic signaling in cardiomyocytes
Vascular smooth muscle contraction
Wnt signaling pathway
Hedgehog signaling pathway
Gap junction
Platelet activation
Circadian entrainment
Long-term potentiation
Retrograde endocannabinoid signaling
Glutamatergic synapse
Cholinergic synapse
Serotonergic synapse
GABAergic synapse
Dopaminergic synapse
Olfactory transduction
Taste transduction
Inflammatory mediator regulation of TRP channels
Insulin signaling pathway
Insulin secretion
GnRH signaling pathway
Ovarian steroidogenesis
Progesterone-mediated oocyte maturation
Estrogen signaling pathway
Melanogenesis
Thyroid hormone synthesis
Thyroid hormone signaling pathway
Oxytocin signaling pathway
Endocrine and other factor-regulated calcium reabsorption
Vasopressin-regulated water reabsorption
Salivary secretion
Gastric acid secretion
Bile secretion
Parkinson's disease
Prion diseases
Cocaine addiction
Amphetamine addiction
Morphine addiction
Amoebiasis
HTLV-I infection
Epstein-Barr virus infection
Viral carcinogenesis
Proteoglycans in cancer
Dilated cardiomyopathy
Brite
KEGG Orthology (KO) [BR:pps00001]
 Environmental Information Processing
  Signal transduction
   04014 Ras signaling pathway
    100968237 (PRKACA)
   04010 MAPK signaling pathway
    100968237 (PRKACA)
   04310 Wnt signaling pathway
    100968237 (PRKACA)
   04340 Hedgehog signaling pathway
    100968237 (PRKACA)
   04020 Calcium signaling pathway
    100968237 (PRKACA)
   04024 cAMP signaling pathway
    100968237 (PRKACA)
 Cellular Processes
  Cell growth and death
   04114 Oocyte meiosis
    100968237 (PRKACA)
   04210 Apoptosis
    100968237 (PRKACA)
  Cellular commiunity
   04540 Gap junction
    100968237 (PRKACA)
 Organismal Systems
  Immune system
   04611 Platelet activation
    100968237 (PRKACA)
   04062 Chemokine signaling pathway
    100968237 (PRKACA)
  Endocrine system
   04911 Insulin secretion
    100968237 (PRKACA)
   04910 Insulin signaling pathway
    100968237 (PRKACA)
   04912 GnRH signaling pathway
    100968237 (PRKACA)
   04913 Ovarian Steroidogenesis
    100968237 (PRKACA)
   04915 Estrogen signaling pathway
    100968237 (PRKACA)
   04914 Progesterone-mediated oocyte maturation
    100968237 (PRKACA)
   04921 Oxytocin signaling pathway
    100968237 (PRKACA)
   04918 Thyroid hormone synthesis
    100968237 (PRKACA)
   04919 Thyroid hormone signaling pathway
    100968237 (PRKACA)
   04916 Melanogenesis
    100968237 (PRKACA)
  Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    100968237 (PRKACA)
   04270 Vascular smooth muscle contraction
    100968237 (PRKACA)
  Digestive system
   04970 Salivary secretion
    100968237 (PRKACA)
   04971 Gastric acid secretion
    100968237 (PRKACA)
   04976 Bile secretion
    100968237 (PRKACA)
  Excretory system
   04962 Vasopressin-regulated water reabsorption
    100968237 (PRKACA)
   04961 Endocrine and other factor-regulated calcium reabsorption
    100968237 (PRKACA)
  Nervous system
   04724 Glutamatergic synapse
    100968237 (PRKACA)
   04727 GABAergic synapse
    100968237 (PRKACA)
   04725 Cholinergic synapse
    100968237 (PRKACA)
   04728 Dopaminergic synapse
    100968237 (PRKACA)
   04726 Serotonergic synapse
    100968237 (PRKACA)
   04720 Long-term potentiation
    100968237 (PRKACA)
   04723 Retrograde endocannabinoid signaling
    100968237 (PRKACA)
  Sensory system
   04740 Olfactory transduction
    100968237 (PRKACA)
   04742 Taste transduction
    100968237 (PRKACA)
   04750 Inflammatory mediator regulation of TRP channels
    100968237 (PRKACA)
  Environmental adaptation
   04713 Circadian entrainment
    100968237 (PRKACA)
 Human Diseases
  Cancers
   05205 Proteoglycans in cancer
    100968237 (PRKACA)
   05203 Viral carcinogenesis
    100968237 (PRKACA)
  Neurodegenerative diseases
   05012 Parkinson's disease
    100968237 (PRKACA)
   05020 Prion diseases
    100968237 (PRKACA)
  Substance dependence
   05030 Cocaine addiction
    100968237 (PRKACA)
   05031 Amphetamine addiction
    100968237 (PRKACA)
   05032 Morphine addiction
    100968237 (PRKACA)
  Cardiovascular diseases
   05414 Dilated cardiomyopathy (DCM)
    100968237 (PRKACA)
  Infectious diseases
   05166 HTLV-I infection
    100968237 (PRKACA)
   05169 Epstein-Barr virus infection
    100968237 (PRKACA)
   05146 Amoebiasis
    100968237 (PRKACA)
Enzymes [BR:pps01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.11  cAMP-dependent protein kinase
     100968237 (PRKACA)
Protein kinases [BR:pps01001]
 Serine/threonine protein kinases: AGC group
  PKA family
   100968237 (PRKACA)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif Motif
Other DBs
NCBI-GI: 
NCBI-GeneID: 
Position
Un
AA seq 343 aa AA seqDB search
MASNSSDVKEFLAKAKEDFLKKWESPAQNTAHLDQFERIKTLGTGSFGRVMLVKHKETGN
HYAMKILDKQKVVKLKQIEHTLNEKRILQAVNFPFLVKLEFSFKDNSNLYMVMEYVPGGE
MFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDQQGYIQVTDFGF
AKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIY
EKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNHKWFATTDWIAIYQ
RKVEAPFIPKFKGPGDTSNFDDYEEEEIRVSINEKCGKEFSEF
NT seq 1032 nt NT seq  +upstreamnt  +downstreamnt
atggcttccaactccagcgatgtgaaagaattcttagccaaagccaaagaagattttctt
aaaaaatgggaaagtcccgctcagaacacagcccacttggatcagtttgaacgaatcaag
accctcggcacgggctccttcgggcgggtgatgctggtgaaacacaaggagaccgggaac
cactatgccatgaagatcctcgacaaacagaaggtggtgaaactgaaacagatcgaacac
accctgaatgaaaagcgcatcctgcaagctgtcaactttccgttcctcgtcaaactcgag
ttctccttcaaggacaactcaaacttatacatggtcatggagtacgtgcccggcggggag
atgttctcacacctacggcggatcggaaggttcagcgagccccatgcccgtttctacgcg
gcccagatcgtcctgacctttgagtatctgcactcgctggatctcatctacagggacctg
aagccggagaatctgctcattgaccagcagggctacattcaggtgacagacttcggtttc
gccaagcgcgtgaagggccgcacttggaccttgtgcggcacccctgagtacctggcccct
gagattatcctgagcaaaggctacaacaaggccgtggactggtgggccctgggggttctt
atctatgaaatggccgctggctacccgcccttcttcgcagaccagcccatccagatctat
gagaagatcgtctctgggaaggtgcggttcccttcccacttcagctctgacttgaaggac
ctgctgcggaacctcctgcaggtagatctcaccaagcgctttgggaacctcaagaatggg
gtcaacgatatcaagaaccacaagtggtttgccacaactgactggattgccatctaccag
aggaaggtggaagctcccttcataccaaagtttaaaggccctggggatacgagtaacttt
gacgactatgaggaagaagaaatccgggtctccatcaatgagaagtgtggcaaggagttt
tctgagttttag

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