KEGG   Pan paniscus (bonobo): 100981268Help
Entry
100981268         CDS       T02283                                 

Gene name
MAPK12
Definition
mitogen-activated protein kinase 12
Orthology
K04441  
p38 MAP kinase [EC:2.7.11.24]
Organism
pps  Pan paniscus (bonobo)
Pathway
MAPK signaling pathway
Rap1 signaling pathway
FoxO signaling pathway
Adrenergic signaling in cardiomyocytes
VEGF signaling pathway
Osteoclast differentiation
Platelet activation
Toll-like receptor signaling pathway
NOD-like receptor signaling pathway
RIG-I-like receptor signaling pathway
T cell receptor signaling pathway
Fc epsilon RI signaling pathway
TNF signaling pathway
Leukocyte transendothelial migration
Neurotrophin signaling pathway
Retrograde endocannabinoid signaling
Dopaminergic synapse
Inflammatory mediator regulation of TRP channels
GnRH signaling pathway
Progesterone-mediated oocyte maturation
Prolactin signaling pathway
Amyotrophic lateral sclerosis (ALS)
Salmonella infection
Pertussis
Leishmaniasis
Chagas disease (American trypanosomiasis)
Toxoplasmosis
Tuberculosis
Hepatitis C
Influenza A
Epstein-Barr virus infection
Proteoglycans in cancer
Brite
KEGG Orthology (KO) [BR:pps00001]
 Environmental Information Processing
  Signal transduction
   04015 Rap1 signaling pathway
    100981268 (MAPK12)
   04010 MAPK signaling pathway
    100981268 (MAPK12)
   04370 VEGF signaling pathway
    100981268 (MAPK12)
   04668 TNF signaling pathway
    100981268 (MAPK12)
   04068 FoxO signaling pathway
    100981268 (MAPK12)
 Organismal Systems
  Immune system
   04611 Platelet activation
    100981268 (MAPK12)
   04620 Toll-like receptor signaling pathway
    100981268 (MAPK12)
   04621 NOD-like receptor signaling pathway
    100981268 (MAPK12)
   04622 RIG-I-like receptor signaling pathway
    100981268 (MAPK12)
   04660 T cell receptor signaling pathway
    100981268 (MAPK12)
   04664 Fc epsilon RI signaling pathway
    100981268 (MAPK12)
   04670 Leukocyte transendothelial migration
    100981268 (MAPK12)
  Endocrine system
   04912 GnRH signaling pathway
    100981268 (MAPK12)
   04914 Progesterone-mediated oocyte maturation
    100981268 (MAPK12)
   04917 Prolactin signaling pathway
    100981268 (MAPK12)
  Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    100981268 (MAPK12)
  Nervous system
   04728 Dopaminergic synapse
    100981268 (MAPK12)
   04723 Retrograde endocannabinoid signaling
    100981268 (MAPK12)
   04722 Neurotrophin signaling pathway
    100981268 (MAPK12)
  Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    100981268 (MAPK12)
  Development
   04380 Osteoclast differentiation
    100981268 (MAPK12)
 Human Diseases
  Cancers
   05205 Proteoglycans in cancer
    100981268 (MAPK12)
  Neurodegenerative diseases
   05014 Amyotrophic lateral sclerosis (ALS)
    100981268 (MAPK12)
  Infectious diseases
   05132 Salmonella infection
    100981268 (MAPK12)
   05133 Pertussis
    100981268 (MAPK12)
   05152 Tuberculosis
    100981268 (MAPK12)
   05164 Influenza A
    100981268 (MAPK12)
   05160 Hepatitis C
    100981268 (MAPK12)
   05169 Epstein-Barr virus infection
    100981268 (MAPK12)
   05145 Toxoplasmosis
    100981268 (MAPK12)
   05140 Leishmaniasis
    100981268 (MAPK12)
   05142 Chagas disease (American trypanosomiasis)
    100981268 (MAPK12)
Enzymes [BR:pps01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.24  mitogen-activated protein kinase
     100981268 (MAPK12)
Protein kinases [BR:pps01001]
 Serine/threonine protein kinases: CMGC group
  MAPK family [OT]
   100981268 (MAPK12)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif Motif
Other DBs
NCBI-GI: 
NCBI-GeneID: 
Position
Un
AA seq 347 aa AA seqDB search
MLGAGTPQMGGAGGGAGGPKGPTGTYGTERPGVAIKKLYRPFQSELFAKRAYRELRLLKH
MRHENVIGLLDVFTPDETLDDFTDFYLVMPFMGTDLGKLMKHEKLGEDRIQFLVYQMLKG
LRYIHAAGIIHRDLKPGNLAVNEDCELKILDFGLARQADSEMTGYVVTRWYRAPEVILNW
MRYTQTVDIWSVGCIMAEMITGKTLFKGSDHLDQLKEIMKVTGTPPAEFVQRLQSDEAKN
YMKGLPELEKKDFASILTNASPLAVNLLEKMLVLDAEQRVTAAEALAHPYFESLHDTEDE
PQVQKYDDSFDDVDRTLDEWKRVTYKEVLSFKPPRQLGARVSKETAL
NT seq 1044 nt NT seq  +upstreamnt  +downstreamnt
atgcttggagcaggcaccccacagatggggggagcagggggaggagctgggggtccaaaa
gggcccacggggacctatggcactgagaggcccggggtggccatcaagaagctgtatcgg
cccttccagtccgagctgttcgccaagcgcgcctaccgcgagctgcgcctgctcaagcac
atgcgccacgagaacgtgatcgggctgctggacgtattcactcctgatgagaccctggat
gacttcacggacttttacctggtgatgccgttcatgggcaccgacctgggcaagctcatg
aaacatgagaagctaggcgaggaccggatccagttcctcgtgtaccagatgctgaagggg
ctgaggtatatccacgctgctggcatcatccacagagacctgaagcccggcaacctggct
gtgaacgaagactgtgagctgaagatcctggacttcggcctggccaggcaggcagacagt
gagatgactgggtacgtggtgacccggtggtaccgggctcccgaggtcatcttgaattgg
atgcgctacacgcagacggtggacatctggtctgtgggctgcatcatggcggagatgatc
acaggcaagacgctgttcaagggcagcgaccacctggaccagctgaaggagatcatgaag
gtgacggggacgcctccggctgagtttgtgcagcggctgcagagcgatgaggccaagaac
tacatgaagggcctccccgaattggagaagaaggattttgcctctatcctgaccaatgca
agccctctggctgtgaacctcctggagaagatgctggtgctggacgcggagcagcgggtg
acagcagccgaggcgctggcccatccctacttcgagtccctgcacgacacggaagatgag
ccccaggtccagaagtatgatgactcctttgacgacgtggaccgcacactggatgaatgg
aagcgtgttacttacaaagaggtgctcagcttcaagcctcctcggcagctgggggccagg
gtctccaaggagacggctctgtga

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