KEGG   Pan paniscus (bonobo): 100982480Help
Entry
100982480         CDS       T02283                                 

Gene name
MAPK8
Definition
mitogen-activated protein kinase 8
Orthology
K04440  
c-Jun N-terminal kinase [EC:2.7.11.24]
Organism
pps  Pan paniscus (bonobo)
Pathway
MAPK signaling pathway
ErbB signaling pathway
Ras signaling pathway
cAMP signaling pathway
FoxO signaling pathway
Protein processing in endoplasmic reticulum
Wnt signaling pathway
Osteoclast differentiation
Focal adhesion
Toll-like receptor signaling pathway
NOD-like receptor signaling pathway
RIG-I-like receptor signaling pathway
Fc epsilon RI signaling pathway
TNF signaling pathway
Neurotrophin signaling pathway
Retrograde endocannabinoid signaling
Dopaminergic synapse
Inflammatory mediator regulation of TRP channels
Insulin signaling pathway
GnRH signaling pathway
Progesterone-mediated oocyte maturation
Prolactin signaling pathway
Adipocytokine signaling pathway
Type II diabetes mellitus
Non-alcoholic fatty liver disease (NAFLD)
Salmonella infection
Pertussis
Chagas disease (American trypanosomiasis)
Toxoplasmosis
Tuberculosis
Hepatitis C
Hepatitis B
Influenza A
Herpes simplex infection
Epstein-Barr virus infection
Pathways in cancer
Colorectal cancer
Pancreatic cancer
Choline metabolism in cancer
Module
MAPK (JNK) signaling
Brite
KEGG Orthology (KO) [BR:pps00001]
 Genetic Information Processing
  Folding, sorting and degradation
   04141 Protein processing in endoplasmic reticulum
    100982480 (MAPK8)
 Environmental Information Processing
  Signal transduction
   04014 Ras signaling pathway
    100982480 (MAPK8)
   04010 MAPK signaling pathway
    100982480 (MAPK8)
   04012 ErbB signaling pathway
    100982480 (MAPK8)
   04310 Wnt signaling pathway
    100982480 (MAPK8)
   04668 TNF signaling pathway
    100982480 (MAPK8)
   04068 FoxO signaling pathway
    100982480 (MAPK8)
   04024 cAMP signaling pathway
    100982480 (MAPK8)
 Cellular Processes
  Cellular commiunity
   04510 Focal adhesion
    100982480 (MAPK8)
 Organismal Systems
  Immune system
   04620 Toll-like receptor signaling pathway
    100982480 (MAPK8)
   04621 NOD-like receptor signaling pathway
    100982480 (MAPK8)
   04622 RIG-I-like receptor signaling pathway
    100982480 (MAPK8)
   04664 Fc epsilon RI signaling pathway
    100982480 (MAPK8)
  Endocrine system
   04910 Insulin signaling pathway
    100982480 (MAPK8)
   04920 Adipocytokine signaling pathway
    100982480 (MAPK8)
   04912 GnRH signaling pathway
    100982480 (MAPK8)
   04914 Progesterone-mediated oocyte maturation
    100982480 (MAPK8)
   04917 Prolactin signaling pathway
    100982480 (MAPK8)
  Nervous system
   04728 Dopaminergic synapse
    100982480 (MAPK8)
   04723 Retrograde endocannabinoid signaling
    100982480 (MAPK8)
   04722 Neurotrophin signaling pathway
    100982480 (MAPK8)
  Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    100982480 (MAPK8)
  Development
   04380 Osteoclast differentiation
    100982480 (MAPK8)
 Human Diseases
  Cancers
   05200 Pathways in cancer
    100982480 (MAPK8)
   05231 Choline metabolism in cancer
    100982480 (MAPK8)
   05210 Colorectal cancer
    100982480 (MAPK8)
   05212 Pancreatic cancer
    100982480 (MAPK8)
  Endocrine and metabolic diseases
   04930 Type II diabetes mellitus
    100982480 (MAPK8)
   04932 Non-alcoholic fatty liver disease (NAFLD)
    100982480 (MAPK8)
  Infectious diseases
   05132 Salmonella infection
    100982480 (MAPK8)
   05133 Pertussis
    100982480 (MAPK8)
   05152 Tuberculosis
    100982480 (MAPK8)
   05164 Influenza A
    100982480 (MAPK8)
   05161 Hepatitis B
    100982480 (MAPK8)
   05160 Hepatitis C
    100982480 (MAPK8)
   05168 Herpes simplex infection
    100982480 (MAPK8)
   05169 Epstein-Barr virus infection
    100982480 (MAPK8)
   05145 Toxoplasmosis
    100982480 (MAPK8)
   05142 Chagas disease (American trypanosomiasis)
    100982480 (MAPK8)
Enzymes [BR:pps01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.24  mitogen-activated protein kinase
     100982480 (MAPK8)
Protein kinases [BR:pps01001]
 Serine/threonine protein kinases: CMGC group
  MAPK family [OT]
   100982480 (MAPK8)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif Motif
Other DBs
NCBI-GI: 
NCBI-GeneID: 
Position
Un
AA seq 427 aa AA seqDB search
MSRSKRDNNFYSVEIGDSTFTVLKRYQNLKPIGSGAQGIVCAAYDAILERNVAIKKLSRP
FQNQTHAKRAYRELVLMKCVNHKNIIGLLNVFTPQKSLEEFQDVYIVMELMDANLCQVIQ
MELDHERMSYLLYQMLCGIKHLHSAGIIHRDLKPSNIVVKSDCTLKILDFGLARTAGTSF
MMTPYVVTRYYRAPEVILGMGYKENVDIWSVGCIMGEMIKGGVLFPGTDHIDQWNKVIEQ
LGTPCPEFMKKLQPTVRTYVENRPKYAGYSFEKLFPDVLFPADSEHNKLKASQARDLLSK
MLVIDASKRISVDEALQHPYINVWYDPSEAEAPPPKIPDKQLDEREHTIEEWKELIYKEV
MDLEERTKNGVIRGQPSPLGAAVINGSQHPSSSSSVNDVSSMSTDPTLASDTDSSLEASA
GPLGCCR
NT seq 1284 nt NT seq  +upstreamnt  +downstreamnt
atgagcagaagcaagcgtgacaacaatttttatagtgtagagattggagattctacattc
acagtcctgaaacgatatcagaatttaaaacctataggctcaggagctcaaggaatagta
tgtgcagcttatgatgccattcttgaaagaaatgttgcaatcaagaagctaagccgacca
tttcagaatcagactcatgccaagcgggcctacagagagctagttcttatgaaatgtgtt
aatcacaaaaatataattggccttttgaatgttttcacaccacagaaatccctagaagaa
tttcaagatgtttacatagtcatggagctcatggatgcaaatctttgccaagtgattcag
atggagctagatcatgaaagaatgtcctaccttctctatcagatgctgtgtggaatcaag
caccttcattctgctggaattattcatcgggacttaaagcccagtaatatagtagtaaaa
tctgactgcactttgaagattcttgacttcggtctggccaggactgcaggaacgagtttt
atgatgacgccttacgtagtgactcgctactacagagcacccgaggtcatccttggcatg
ggctacaaggaaaacgttgacatttggtcagttgggtgcatcatgggagaaatgatcaaa
ggtggtgttttgttcccaggtacagatcatattgatcagtggaataaagttattgaacag
cttggaacaccatgtcctgaattcatgaagaaactgcaaccaacagtaaggacttacgtt
gaaaacagacctaaatatgctggatatagctttgagaaactcttccctgatgtccttttc
ccagctgactcagaacacaacaaacttaaagccagtcaggcaagggatttgttatccaaa
atgctggtaatagatgcatctaaaaggatctctgtagatgaagctctccaacacccgtac
atcaatgtctggtatgatccttctgaagcagaagctccaccaccaaagatccctgacaag
cagttagatgaaagggaacacacaatagaagagtggaaagaattgatatataaggaagtt
atggacttggaggagagaaccaagaatggagttatacgggggcagccctctcctttaggt
gcagcagtgatcaatggctctcagcatccatcgtcatcgtcgtctgtcaatgatgtgtct
tcaatgtcaacagatccgactttggcctctgatacagacagcagtctagaagcatcagct
gggcctctgggctgctgtagatga

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