KEGG   Pan paniscus (bonobo): 100989732Help
Entry
100989732         CDS       T02283                                 

Gene name
PIK3CD
Definition
phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta
Orthology
K00922  
phosphatidylinositol-4,5-bisphosphate 3-kinase [EC:2.7.1.153]
Organism
pps  Pan paniscus (bonobo)
Pathway
Inositol phosphate metabolism
ErbB signaling pathway
Ras signaling pathway
Rap1 signaling pathway
cGMP-PKG signaling pathway
Chemokine signaling pathway
HIF-1 signaling pathway
FoxO signaling pathway
Phosphatidylinositol signaling system
mTOR signaling pathway
PI3K-Akt signaling pathway
AMPK signaling pathway
Apoptosis
Adrenergic signaling in cardiomyocytes
VEGF signaling pathway
Osteoclast differentiation
Focal adhesion
Platelet activation
Toll-like receptor signaling pathway
Jak-STAT signaling pathway
Natural killer cell mediated cytotoxicity
T cell receptor signaling pathway
B cell receptor signaling pathway
Fc epsilon RI signaling pathway
Fc gamma R-mediated phagocytosis
TNF signaling pathway
Leukocyte transendothelial migration
Neurotrophin signaling pathway
Cholinergic synapse
Inflammatory mediator regulation of TRP channels
Regulation of actin cytoskeleton
Insulin signaling pathway
Progesterone-mediated oocyte maturation
Estrogen signaling pathway
Prolactin signaling pathway
Thyroid hormone signaling pathway
Oxytocin signaling pathway
Type II diabetes mellitus
Non-alcoholic fatty liver disease (NAFLD)
Aldosterone-regulated sodium reabsorption
Carbohydrate digestion and absorption
Bacterial invasion of epithelial cells
Chagas disease (American trypanosomiasis)
Toxoplasmosis
Amoebiasis
Hepatitis C
Hepatitis B
Measles
Influenza A
HTLV-I infection
Epstein-Barr virus infection
Pathways in cancer
Viral carcinogenesis
Proteoglycans in cancer
Colorectal cancer
Renal cell carcinoma
Pancreatic cancer
Endometrial cancer
Glioma
Prostate cancer
Melanoma
Chronic myeloid leukemia
Acute myeloid leukemia
Small cell lung cancer
Non-small cell lung cancer
Brite
KEGG Orthology (KO) [BR:pps00001]
 Metabolism
  Carbohydrate metabolism
   00562 Inositol phosphate metabolism
    100989732 (PIK3CD)
 Environmental Information Processing
  Signal transduction
   04014 Ras signaling pathway
    100989732 (PIK3CD)
   04015 Rap1 signaling pathway
    100989732 (PIK3CD)
   04012 ErbB signaling pathway
    100989732 (PIK3CD)
   04370 VEGF signaling pathway
    100989732 (PIK3CD)
   04630 Jak-STAT signaling pathway
    100989732 (PIK3CD)
   04668 TNF signaling pathway
    100989732 (PIK3CD)
   04066 HIF-1 signaling pathway
    100989732 (PIK3CD)
   04068 FoxO signaling pathway
    100989732 (PIK3CD)
   04070 Phosphatidylinositol signaling system
    100989732 (PIK3CD)
   04022 cGMP - PKG signaling pathway
    100989732 (PIK3CD)
   04151 PI3K-Akt signaling pathway
    100989732 (PIK3CD)
   04152 AMPK signaling pathway
    100989732 (PIK3CD)
   04150 mTOR signaling pathway
    100989732 (PIK3CD)
 Cellular Processes
  Cell motility
   04810 Regulation of actin cytoskeleton
    100989732 (PIK3CD)
  Cell growth and death
   04210 Apoptosis
    100989732 (PIK3CD)
  Cell communication
   04510 Focal adhesion
    100989732 (PIK3CD)
 Organismal Systems
  Immune system
   04611 Platelet activation
    100989732 (PIK3CD)
   04620 Toll-like receptor signaling pathway
    100989732 (PIK3CD)
   04650 Natural killer cell mediated cytotoxicity
    100989732 (PIK3CD)
   04660 T cell receptor signaling pathway
    100989732 (PIK3CD)
   04662 B cell receptor signaling pathway
    100989732 (PIK3CD)
   04664 Fc epsilon RI signaling pathway
    100989732 (PIK3CD)
   04666 Fc gamma R-mediated phagocytosis
    100989732 (PIK3CD)
   04670 Leukocyte transendothelial migration
    100989732 (PIK3CD)
   04062 Chemokine signaling pathway
    100989732 (PIK3CD)
  Endocrine system
   04910 Insulin signaling pathway
    100989732 (PIK3CD)
   04915 Estrogen signaling pathway
    100989732 (PIK3CD)
   04914 Progesterone-mediated oocyte maturation
    100989732 (PIK3CD)
   04917 Prolactin signaling pathway
    100989732 (PIK3CD)
   04921 Oxytocin signaling pathway
    100989732 (PIK3CD)
   04919 Thyroid hormone signaling pathway
    100989732 (PIK3CD)
  Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    100989732 (PIK3CD)
  Digestive system
   04973 Carbohydrate digestion and absorption
    100989732 (PIK3CD)
  Excretory system
   04960 Aldosterone-regulated sodium reabsorption
    100989732 (PIK3CD)
  Nervous system
   04725 Cholinergic synapse
    100989732 (PIK3CD)
   04722 Neurotrophin signaling pathway
    100989732 (PIK3CD)
  Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    100989732 (PIK3CD)
  Development
   04380 Osteoclast differentiation
    100989732 (PIK3CD)
 Human Diseases
  Cancers
   05200 Pathways in cancer
    100989732 (PIK3CD)
   05205 Proteoglycans in cancer
    100989732 (PIK3CD)
   05203 Viral carcinogenesis
    100989732 (PIK3CD)
   05210 Colorectal cancer
    100989732 (PIK3CD)
   05212 Pancreatic cancer
    100989732 (PIK3CD)
   05214 Glioma
    100989732 (PIK3CD)
   05221 Acute myeloid leukemia
    100989732 (PIK3CD)
   05220 Chronic myeloid leukemia
    100989732 (PIK3CD)
   05218 Melanoma
    100989732 (PIK3CD)
   05211 Renal cell carcinoma
    100989732 (PIK3CD)
   05215 Prostate cancer
    100989732 (PIK3CD)
   05213 Endometrial cancer
    100989732 (PIK3CD)
   05222 Small cell lung cancer
    100989732 (PIK3CD)
   05223 Non-small cell lung cancer
    100989732 (PIK3CD)
  Endocrine and metabolic diseases
   04930 Type II diabetes mellitus
    100989732 (PIK3CD)
   04932 Non-alcoholic fatty liver disease (NAFLD)
    100989732 (PIK3CD)
  Infectious diseases
   05100 Bacterial invasion of epithelial cells
    100989732 (PIK3CD)
   05166 HTLV-I infection
    100989732 (PIK3CD)
   05162 Measles
    100989732 (PIK3CD)
   05164 Influenza A
    100989732 (PIK3CD)
   05161 Hepatitis B
    100989732 (PIK3CD)
   05160 Hepatitis C
    100989732 (PIK3CD)
   05169 Epstein-Barr virus infection
    100989732 (PIK3CD)
   05146 Amoebiasis
    100989732 (PIK3CD)
   05145 Toxoplasmosis
    100989732 (PIK3CD)
   05142 Chagas disease (American trypanosomiasis)
    100989732 (PIK3CD)
Enzymes [BR:pps01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.1  Phosphotransferases with an alcohol group as acceptor
    2.7.1.153  phosphatidylinositol-4,5-bisphosphate 3-kinase
     100989732 (PIK3CD)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif Motif
Other DBs
NCBI-GI: 
NCBI-GeneID: 
Position
Un
AA seq 1068 aa AA seqDB search
MPPGVDCPMEFWTKEENQSVVVDFLLPTGVYLNFPVSRNANLSTIKQLLWHRAQYEPLFH
MLSGPEAYVFTCINQTAEQQELEDEQRRLCDVQPFLPVLRLVAREGDRVKKLINSQISLL
IGKGLHEFDSLCDPEVNDFRAKMCQFCEEAAARRQQLGWEAWLQYSFPLQLEPSARTWGP
GTLRLPNRALLVNVKFEGSEESFTFQVSTKDVPLALMACALRKKATVFRQPLVEQPEDYT
LQVNGRHEYLYGSYPLCQFQVQKPRAKPPPIPAKKPSSVSLWSLEQPFRIELIQGSKVNA
DERMKLVVQAGLFHGNEMLCKTVSSSEVSVCSEPVWKQRLEFDINICDLPRMARLCFALY
AVIEKAKKARSTKKKSKKADCPIAWANLMLFDYKDQLKTGERCLYMWPSVPDEKGELLNP
TGTVRSNPNTDSAAALLICLPEVAPHPVYYPALEKLPGGMLLASCEWRPELLWMRLHAED
SAPSRMIGVAMPGLGVLPGLVQAPGDAECSCLLQILELGRHSECVHVTEEEQLQLREILE
RRGSGELYEHEKDLVWKLRHEIQEHFPEALARLLLVTKWNKHEDVAQMLYLLCSWPELPV
LSALELLDFSFPDCHVGSFAIKSLRKLTDDELFQYLLQLVQVLKYESYLDCELTKFLLDR
ALANRKIGHFLFWHLRSEMHVPSVALRFGLILEAYCRGSTHHMKVLMKQGEALSKLKALN
DFVKLSSQKTPKPQTKELMHLCMRQEAYLEALSHLQSPLDPSTLLAEVCVEQCTFMDSKM
KPLWIMYSNEEAGSGGSVGIIFKNGDDLRQDMLTLQMIQLMDVLWKQEGLDLRMTPYGCL
PTGDRTGLIEVVLRSDTIANIQLNKSNMAATAAFNKDALLNWLKSKNPGEALDRAIEEFT
LSCAGYCVATYVLGIGDRHSDNIMIRESGQLFHIDFGHFLGNFKTKFGINRERVPFILTY
DFVHVIQQGKTNNSEKFERFRGYCERAYTILRRHGLLFLHLFALMRAAGLPELSCSKDIQ
YLKDSLALGKTEEEALKHFRVKFNEALRESWKTKVNWLAHNVSKDNRQ
NT seq 3207 nt NT seq  +upstreamnt  +downstreamnt
atgccccctggggtggactgccccatggaattctggaccaaggaggagaatcagagcgtc
gtggttgacttcctgctgcccacaggggtctacctgaacttccctgtgtcccgcaatgcc
aacctcagcaccatcaagcagctgctgtggcaccgcgcccagtatgagccgctcttccac
atgctcagtggccccgaggcctatgtgttcacctgcatcaaccagacagcggagcagcaa
gagctggaggacgagcaacggcgtctgtgtgacgtgcagcccttcctgcccgtcctgcgc
ctggtggcccgtgagggcgaccgcgtgaagaagctcatcaactcacagatcagcctcctc
atcggcaaaggcctccacgagtttgactccttgtgcgacccagaagtgaacgactttcgc
gccaagatgtgccaattctgcgaggaggcggccgcccgccggcagcagctgggctgggag
gcctggctgcagtacagtttccccctgcagctggagccctcggctcgaacctgggggcct
ggcaccctgcggctcccaaaccgggcccttctggtcaacgttaagtttgagggcagcgag
gagagcttcaccttccaggtgtccaccaaggacgtgccgctggcgctgatggcctgtgcc
ctgcggaagaaggccacggtgttccggcagccgctggtggagcagccggaagactacacg
ctgcaggtgaacggcaggcatgagtacctgtatggcagctacccgctctgccagttccag
gtccagaaaccgcgtgccaaaccacctcccattcctgcgaagaagccttcctctgtgtcc
ctgtggtccctggagcagccgttccgcatcgagctcatccagggcagcaaagtgaacgcc
gacgagcggatgaagctggtggtgcaggccgggcttttccacggcaacgagatgctgtgc
aagacggtgtccagctcggaggtgagcgtgtgctcggagcccgtgtggaagcagcggctg
gagttcgacatcaacatctgtgacctgccccgcatggcccgtctctgctttgcgctgtac
gccgtgatcgagaaagccaagaaggctcgctccaccaagaagaagtccaagaaggcggac
tgccccattgcctgggccaacctcatgctgtttgactacaaggaccagcttaagaccggg
gaacgctgcctctatatgtggccctccgtcccagatgagaagggcgagctgctgaacccc
acgggcactgtgcgcagtaaccccaacacggatagcgccgccgccctgctcatctgcctg
cccgaggtggccccgcaccccgtgtactaccctgccctggagaagctgccgggagggatg
ctcttggcatcttgtgagtggaggccagagctgctgtggatgcgcctccatgcagaggac
agcgccccctcaaggatgatcggggtggcaatgcccggcctgggggtcctgcccgggctg
gtccaggcccctggggacgctgagtgcagctgtttgttgcagatcttggagctggggcga
cacagcgagtgtgtgcatgtcactgaggaggagcagctgcagctgcgggaaatcctggag
cggcgggggtctggggagttgtatgagcacgagaaggacctggtgtggaagctgcggcat
gaaatccaggagcacttcccggaggcgctagcccggctgctgctggtcaccaagtggaac
aagcatgaggatgtggcccagatgctctacctgctgtgctcctggccggagctgcccgtc
ctgagcgccctggagctgctagacttcagcttccccgattgccacgtaggctccttcgcc
atcaagtcgctgaggaaactgacggacgatgagctgttccagtacctgctgcagctggtg
caggtgctcaagtacgagtcctacctggactgcgagctgaccaaattcctgctggaccgg
gccctggccaaccgcaagatcggccacttccttttctggcacctccgctccgagatgcac
gtgccgtcggtggccctgcgcttcggcctcatcctggaggcctactgcaggggcagcacc
caccacatgaaggtgctgatgaagcagggggaagcactgagcaaactgaaggccctgaat
gacttcgtcaagctgagctctcagaagacccccaagccccagaccaaggagctgatgcac
ttgtgcatgcggcaggaggcctacctagaggccctctcccacctgcagtccccactcgac
cccagcaccctgctggctgaagtctgcgtggagcagtgcaccttcatggactccaagatg
aagcccctgtggatcatgtacagcaacgaggaggcaggcagtggcggcagcgtgggcatc
atctttaagaacggggatgacctccggcaggacatgctgaccctgcagatgatccagctc
atggacgtcctgtggaagcaggaggggctggacctgaggatgaccccctacggctgcctc
cccaccggggaccgcacaggcctcattgaggtggtactccgttcagacaccatcgccaac
atccaactcaacaagagcaacatggcagccacagccgccttcaacaaggacgccctgctc
aactggctgaagtccaagaacccgggggaggccctggatcgagccattgaggagttcacc
ctctcctgtgctggctattgtgtggccacatatgtgctgggcatcggcgatcggcacagc
gacaacatcatgatccgagagagtgggcagctgttccacattgattttggccactttctg
gggaatttcaagaccaagtttggaatcaaccgcgagcgtgtcccattcatcctcacctat
gactttgtccatgtgattcagcaggggaagactaataatagtgagaaatttgaacggttc
cggggctactgtgaaagggcctacaccatcctgcggcgccacgggcttctcttcctccac
ctctttgccctgatgcgggcggcaggcctgcctgagctcagctgctccaaagacatccag
tatctcaaggactccctggcactggggaaaacagaggaggaggcactgaagcacttccga
gtgaagtttaacgaagccctccgtgagagctggaaaaccaaagtgaactggctggcccat
aacgtgtccaaagacaacaggcagtag

DBGET integrated database retrieval system