KEGG   Pan paniscus (bonobo): 100991777
Entry
100991777         CDS       T02283                                 
Symbol
MET
Name
(RefSeq) hepatocyte growth factor receptor isoform X1
  KO
K05099  proto-oncogene tyrosine-protein kinase Met [EC:2.7.10.1]
Organism
pps  Pan paniscus (bonobo)
Pathway
pps01521  EGFR tyrosine kinase inhibitor resistance
pps04010  MAPK signaling pathway
pps04014  Ras signaling pathway
pps04015  Rap1 signaling pathway
pps04020  Calcium signaling pathway
pps04151  PI3K-Akt signaling pathway
pps04360  Axon guidance
pps04510  Focal adhesion
pps04520  Adherens junction
pps05100  Bacterial invasion of epithelial cells
pps05144  Malaria
pps05200  Pathways in cancer
pps05202  Transcriptional misregulation in cancer
pps05205  Proteoglycans in cancer
pps05206  MicroRNAs in cancer
pps05208  Chemical carcinogenesis - reactive oxygen species
pps05211  Renal cell carcinoma
pps05218  Melanoma
pps05223  Non-small cell lung cancer
pps05225  Hepatocellular carcinoma
pps05226  Gastric cancer
pps05230  Central carbon metabolism in cancer
Brite
KEGG Orthology (KO) [BR:pps00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    100991777 (MET)
   04014 Ras signaling pathway
    100991777 (MET)
   04015 Rap1 signaling pathway
    100991777 (MET)
   04020 Calcium signaling pathway
    100991777 (MET)
   04151 PI3K-Akt signaling pathway
    100991777 (MET)
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    100991777 (MET)
   04520 Adherens junction
    100991777 (MET)
 09150 Organismal Systems
  09158 Development and regeneration
   04360 Axon guidance
    100991777 (MET)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    100991777 (MET)
   05202 Transcriptional misregulation in cancer
    100991777 (MET)
   05206 MicroRNAs in cancer
    100991777 (MET)
   05205 Proteoglycans in cancer
    100991777 (MET)
   05208 Chemical carcinogenesis - reactive oxygen species
    100991777 (MET)
   05230 Central carbon metabolism in cancer
    100991777 (MET)
  09162 Cancer: specific types
   05225 Hepatocellular carcinoma
    100991777 (MET)
   05226 Gastric cancer
    100991777 (MET)
   05218 Melanoma
    100991777 (MET)
   05211 Renal cell carcinoma
    100991777 (MET)
   05223 Non-small cell lung cancer
    100991777 (MET)
  09171 Infectious disease: bacterial
   05100 Bacterial invasion of epithelial cells
    100991777 (MET)
  09174 Infectious disease: parasitic
   05144 Malaria
    100991777 (MET)
  09176 Drug resistance: antineoplastic
   01521 EGFR tyrosine kinase inhibitor resistance
    100991777 (MET)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:pps01001]
    100991777 (MET)
Enzymes [BR:pps01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.10  Protein-tyrosine kinases
    2.7.10.1  receptor protein-tyrosine kinase
     100991777 (MET)
Protein kinases [BR:pps01001]
 Receptor tyrosine kinases (RTK)
  MET family
   100991777 (MET)
SSDB
Motif
Pfam: PK_Tyr_Ser-Thr TIG Pkinase Sema PSI Kinase-like Pkinase_fungal Linker_histone
Other DBs
NCBI-GeneID: 100991777
NCBI-ProteinID: XP_034820753
Ensembl: ENSPPAG00000038004
Position
7:108646278..108772238
AA seq 1409 aa
MKSKSKSLAECLPHDKPLIMKAPAVLAPGILVLLFTLVQRSNGECKEALAKSEMNVNMKY
QLPNFTAETPIQNVILHEHHIFLGATNYIYVLNEEDLQKVAEYKTGPVLEHPDCFPCQDC
SSKANLSGGVWKDNINMALVVDTYYDDQLISCGSVNRGTCQRHVFPHNHTADIQSEVHCI
FSPQIEEPSQCPDCVVSALGAKVLSSVKDRFINFFVGNTINSSYFPDHPLHSISVRRLKE
TKDGFMFLTDQSYIDVLPEFRDSYPIKYVHAFESNNFIYFLTVQRETLDAQTFHTRIIRF
CSINSGLHSYMEMPLECILTEKRKKRSTKKEVFNILQAAYVSKPGAQLARQIGASLNDDI
LFGVFAQSKPDSAEPMDRSAMCAFPIKYVNDFFNKIVNKNNVRCLQHFYGPNHEHCFNRT
LLRNSSSCEARRDEYRTEFTTALQRVDLFMGQFSEVLLTSISTFIKGDLTIANLGTSEGR
FMQVVVSRSGPSTPHVNFLLDSHPVSPEVIVEHTLNQNGYTLVVTGKKITKIPLNGLGCR
HFQSCSQCLSAPPFVQCGWCHDKCVRSEECLSGTWTQQICLPAIYKVFPNSAPLEGGTRL
TICGWDFGFRRNNKFDLKKTRVLLGNESCTLTLSESTMNTLKCTVGPAMNKHFNMSIIIS
NGHGTTQYSTFSYVDPVITSISPKYGPMAGGTLLTLTGNYLNSGNSRHISIGGKTCTLKS
VSNSILECYTPAQTISTEFAVKLKIDLANRETSIFSYREDPIVYEIHPTKSFISGGSTIT
GVGKNLNSVSVPRMVINVHEAGRNFTVACQHRSNSEIICCTTPSLQQLNLQLPLKTKAFF
MLDGILSKYFDLIYVHNPVFKPFEKPVMISMGNENVLEIKGNDIDPEAVKGEVLKVGNKS
CENIHLHSEAVLCTVPNDLLKLNSELNIEWKQAISSTVLGKVIVQPDQNFTGLIAGVVSI
SIALLLLLGFFLWLKKRKQIKDLGSELVRYDARVHTPHLDRLVSARSVSPTTEMVSNESV
DYRATFPEDQFPNSSQNGSCRQVQYPLTDMSPILTSGDSDISSPLLQNTVHIDLSALNPE
LVQAVQHVVIGPSSLIVHFNEVIGRGHFGCVYHGTLLDNDGKKIHCAVKSLNRITDIGEV
SQFLTEGIIMKDFSHPNVLSLLGICLRSEGSPLVVLPYMKHGDLRNFIRNETHNPTVKDL
IGFGLQVAKGMKYLASKKFVHRDLAARNCMLDEKFTVKVADFGLARDMYDKEYYSVHNKT
GAKLPVKWMALESLQTQKFTTKSDVWSFGVLLWELMTRGAPPYPDVNTFDITVYLLQGRR
LLQPEYCPDPLYEVMLKCWHPKAEMRPSFSELVSRISAIFSTFIGEHYVHVNATYVNVKC
VAPYPSLLSSEDNADDEVDTRPASFWETS
NT seq 4230 nt   +upstreamnt  +downstreamnt
atgaagagtaaatcaaagagtttagcagaatgcctcccacatgataaacctctcataatg
aaggcccccgctgtgcttgcacctggcatcctcgtgctcctgtttaccttggtgcagagg
agcaatggggagtgtaaagaggcactagcaaagtccgagatgaatgtgaatatgaagtat
cagcttcccaacttcaccgcggaaacacccatccagaatgtcattctacatgagcatcac
attttcctcggtgccactaactacatttatgttttaaatgaggaagaccttcagaaggtt
gctgagtacaagactgggcctgtgctggaacacccagattgtttcccatgtcaggactgc
agcagcaaagccaatttatcaggaggtgtttggaaagataacatcaacatggctctagtt
gtcgacacctactatgatgatcaactcattagctgtggcagcgtcaacagagggacctgc
cagcgacatgtctttccccacaatcatactgctgacatacagtcggaggttcactgcata
ttctccccacagatagaagagcccagccagtgtcctgactgtgtggtgagcgccctggga
gccaaagtcctttcatctgtaaaggaccggttcatcaacttctttgtaggcaataccata
aattcttcttatttcccagatcatccgttgcattcaatatcagtgagaaggctaaaggaa
acgaaagatggttttatgtttttgacagaccagtcctacattgatgttttacctgagttc
agagattcttaccccattaagtatgtccatgcctttgaaagcaacaattttatttacttc
ttgacggtccaaagggaaactctagatgctcagacttttcacacaagaataatcaggttc
tgttccataaactctggattgcattcctacatggaaatgcctctggagtgtattctcaca
gaaaagagaaaaaagagatccacaaagaaggaagtgtttaatatccttcaggctgcgtat
gtcagcaagcctggggcccagcttgctagacaaataggagccagcctgaatgatgacatt
cttttcggggtgttcgcacaaagcaagccagattctgccgaaccaatggatcgatctgcc
atgtgtgcattccctatcaaatatgtcaacgacttcttcaacaagatcgtcaacaaaaac
aatgtgagatgtctccagcatttttacggacccaatcatgagcactgttttaataggaca
cttctgagaaattcatcaagctgtgaagcgcgccgtgatgaatatcgaacagagtttacc
acagctttgcagcgcgttgacttattcatgggtcaattcagcgaagtcctcttaacatct
atatccaccttcattaaaggagacctcaccatagctaatcttgggacatcagagggtcgc
ttcatgcaggttgtggtttctcgatcaggaccatcaacccctcatgtgaattttctcctg
gactcccatccagtgtctccagaagtgattgtggagcatacattaaaccagaatggctac
acactggttgtcactgggaagaagatcacgaagatcccattgaatggcttgggctgcaga
catttccagtcctgcagtcagtgcctctctgccccaccctttgttcagtgtggctggtgc
cacgacaaatgtgtgcgatcggaggaatgcctgagcgggacatggactcaacagatctgt
ctgcctgcaatctacaaggttttcccaaatagtgcaccccttgaaggagggacaaggctg
accatatgtggctgggactttggatttcggaggaataataaatttgatttaaagaaaact
agagttctccttggaaatgagagctgcaccttgactttaagtgagagcacgatgaataca
ttgaaatgcacagttggtcctgccatgaataagcatttcaatatgtccataattatttca
aatggccacgggacaacacaatacagtacattctcctatgtggatcctgtaataacaagt
atttcgccgaaatacggtcctatggctggtggcactttacttactttaactggaaattac
ctaaacagtgggaattctagacacatttcaattggtggaaaaacatgtactttaaaaagt
gtgtcaaacagtattcttgaatgttataccccagcccaaaccatttcaactgagtttgct
gttaaattgaaaattgacttagccaaccgagagacaagcatcttcagttaccgggaagat
cccattgtctatgaaattcatccaaccaaatcttttattagtggtgggagcacaataaca
ggtgttgggaaaaacctgaattcagttagtgtcccgaggatggtcataaatgtgcatgaa
gcaggaaggaattttacagtggcatgtcaacatcgctctaattcagagataatctgttgt
accactccttccctgcaacagctgaatctgcaactccccctgaaaaccaaagcctttttc
atgttagatgggatcctttccaaatactttgatctcatttatgtacataatcctgtgttt
aagccttttgaaaagccagtgatgatctcaatgggcaatgaaaatgtactggaaattaag
ggaaatgatattgaccctgaagcagttaaaggtgaagtgttaaaagttggaaataagagc
tgtgagaatatacacttacattctgaagccgttttatgcacggtccccaatgacctgctg
aaattgaacagcgagctaaatatagagtggaagcaagcaatttcttcaaccgtccttgga
aaagtaatagttcaaccagatcagaatttcacaggattgattgctggtgttgtctcaata
tcaatagcactgttattactacttgggtttttcctgtggctgaaaaagagaaagcaaatt
aaagatctgggcagtgaattagttcgctacgatgcaagagtacacactcctcatttggat
aggctcgtaagtgcccgaagtgtaagcccaactacagaaatggtttcaaatgaatctgta
gactaccgagctacttttccagaagatcagtttcctaattcatctcagaacggttcatgc
cgacaagtgcagtatcctctgacagacatgtcccccatcctaactagtggggactctgat
atatccagtccattactgcaaaatactgtccacattgacctcagtgctctaaatccagag
ctggtccaggcagtgcagcatgtagtgattgggcccagtagcctgattgtgcatttcaat
gaagtcataggaagagggcattttggttgtgtatatcatgggactttgttggacaatgat
ggcaagaaaattcactgtgctgtgaaatccttgaacagaatcactgacataggagaagtt
tcccaatttctgaccgagggaatcatcatgaaagattttagtcatcccaatgtcctctcg
ctcctgggaatctgcctgcgaagtgaagggtctccgctggtggtcctaccatacatgaaa
catggagatcttcgaaatttcattcgaaatgagactcataatccaactgtaaaagatctt
attggctttggtcttcaagtagccaaaggcatgaaatatcttgcaagcaaaaagtttgtc
cacagagacttggctgcaagaaactgtatgctggatgaaaaattcacagtcaaggttgct
gattttggtcttgccagagacatgtatgataaagaatactatagtgtacacaacaaaaca
ggtgcaaagctgccagtgaagtggatggctttggaaagtctgcaaactcaaaagtttacc
accaagtcagatgtgtggtcctttggcgtgctcctctgggagctgatgacaagaggagcc
ccaccttatcctgatgtgaacacctttgatataactgtttacttgttgcaagggagaagg
ctcctacaacccgaatactgcccagaccccttatacgaagtaatgctaaaatgctggcac
cctaaagccgaaatgcgcccatccttttctgaactggtgtcccggatatcagcgatcttc
tctactttcattggggagcactatgtccatgtgaacgctacttatgtgaacgtaaaatgt
gtcgctccatatccttctctgttgtcatcagaagataacgctgatgatgaggtggacaca
cgaccagcctccttctgggagacatcatag

  All links  
Ontology (3)   
   KEGG BRITE (3)   
Pathway (22)   
   KEGG PATHWAY (22)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (5)   
   KEGG ORTHOLOGY (1)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   Ensembl (1)   
   OC (1)   
Protein sequence (3)   
   RefSeq(pep) (3)   
DNA sequence (3)   
   RefSeq(nuc) (3)   
Protein domain (8)   
   Pfam (8)   
All databases (46)   

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