KEGG   Pan paniscus (bonobo): 100992725Help
Entry
100992725         CDS       T02283                                 

Gene name
GSTM1
Definition
(RefSeq) glutathione S-transferase Mu 1
  KO
K00799  glutathione S-transferase [EC:2.5.1.18]
Organism
pps  Pan paniscus (bonobo)
Pathway
pps00480  Glutathione metabolism
pps00980  Metabolism of xenobiotics by cytochrome P450
pps00982  Drug metabolism - cytochrome P450
pps00983  Drug metabolism - other enzymes
pps01524  Platinum drug resistance
pps05200  Pathways in cancer
pps05204  Chemical carcinogenesis
pps05225  Hepatocellular carcinoma
pps05418  Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:pps00001]
 Metabolism
  Metabolism of other amino acids
   00480 Glutathione metabolism
    100992725 (GSTM1)
  Xenobiotics biodegradation and metabolism
   00980 Metabolism of xenobiotics by cytochrome P450
    100992725 (GSTM1)
   00982 Drug metabolism - cytochrome P450
    100992725 (GSTM1)
   00983 Drug metabolism - other enzymes
    100992725 (GSTM1)
 Human Diseases
  Cancers
   05200 Pathways in cancer
    100992725 (GSTM1)
   05204 Chemical carcinogenesis
    100992725 (GSTM1)
   05225 Hepatocellular carcinoma
    100992725 (GSTM1)
  Cardiovascular diseases
   05418 Fluid shear stress and atherosclerosis
    100992725 (GSTM1)
  Drug resistance
   01524 Platinum drug resistance
    100992725 (GSTM1)
Enzymes [BR:pps01000]
 2. Transferases
  2.5  Transferring alkyl or aryl groups, other than methyl groups
   2.5.1  Transferring alkyl or aryl groups, other than methyl groups (only sub-subclass identified to date)
    2.5.1.18  glutathione transferase
     100992725 (GSTM1)
Transporters [BR:pps02000]
 Other Transporters
  Pores ion channels [TC:1]
   100992725 (GSTM1)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif
Pfam: GST_N GST_C_3 GST_C GST_C_6 GST_C_2 GST_N_3
Motif
Other DBs
NCBI-GeneID: 100992725
NCBI-ProteinID: XP_003810690
Position
1
AA seq 218 aa AA seqDB search
MPMTLGYWDIRGLAHAIRLLLEYTDSSYEEKKYSMGDAPDYDRSQWLNEKFKLGLDFPNL
PYLIDGAHKITQSNAILCYIARKHNLCGETEEEKIRVDILENQTMDNHMQLGMICYNPEF
EKLKPKYLEELPEKLKLYSEFLGKRPWFAGNKITFVDFLVYDVLDLHRIFEPKCLDAFPN
LKDFISRFEGLEKISAYMKSSRFLPRPVFTKMAVWGNK
NT seq 657 nt NT seq  +upstreamnt  +downstreamnt
atgcccatgacactggggtactgggacatccgcgggctggcccacgccatccgcctgctc
ctggaatacacagactcaagctatgaggaaaagaagtactcgatgggggacgctcctgac
tatgacagaagccagtggctgaatgaaaaattcaagctgggcctggactttcccaatctg
ccctacttgattgatggggctcacaagatcacccagagcaacgccatcttgtgctacatt
gcccgcaagcacaacctgtgtggggagacagaagaggagaagattcgtgtggacattttg
gagaaccagaccatggacaaccatatgcagctgggcatgatctgctacaatccagaattt
gagaaactgaagccaaagtacttggaggaactccctgaaaagctaaagctctactcagag
tttctggggaagcggccatggtttgcaggaaacaagatcacttttgtagattttctcgtc
tatgatgtccttgacctccaccgtatatttgagcccaagtgcttggacgccttcccaaat
ctgaaggacttcatctcccgctttgagggcttggagaagatctctgcctacatgaagtcc
agccgcttcctcccaagacctgtgttcacaaagatggctgtctggggcaacaagtag

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