KEGG   Pan paniscus (bonobo): 100995010Help
Entry
100995010         CDS       T02283                                 

Gene name
PLCG1
Definition
phospholipase C, gamma 1
Orthology
K01116  
phosphatidylinositol phospholipase C, gamma-1 [EC:3.1.4.11]
Organism
pps  Pan paniscus (bonobo)
Pathway
Inositol phosphate metabolism
Metabolic pathways
ErbB signaling pathway
Ras signaling pathway
Rap1 signaling pathway
Calcium signaling pathway
NF-kappa B signaling pathway
HIF-1 signaling pathway
Phosphatidylinositol signaling system
VEGF signaling pathway
Natural killer cell mediated cytotoxicity
T cell receptor signaling pathway
Fc epsilon RI signaling pathway
Fc gamma R-mediated phagocytosis
Leukocyte transendothelial migration
Neurotrophin signaling pathway
Inflammatory mediator regulation of TRP channels
Thyroid hormone signaling pathway
Epstein-Barr virus infection
Pathways in cancer
Proteoglycans in cancer
MicroRNAs in cancer
Glioma
Non-small cell lung cancer
Choline metabolism in cancer
Module
Inositol phosphate metabolism, PI=> PIP2 => Ins(1,4,5)P3 => Ins(1,3,4,5)P4
Brite
KEGG Orthology (KO) [BR:pps00001]
 Metabolism
  Carbohydrate metabolism
   00562 Inositol phosphate metabolism
    100995010 (PLCG1)
 Environmental Information Processing
  Signal transduction
   04014 Ras signaling pathway
    100995010 (PLCG1)
   04015 Rap1 signaling pathway
    100995010 (PLCG1)
   04012 ErbB signaling pathway
    100995010 (PLCG1)
   04370 VEGF signaling pathway
    100995010 (PLCG1)
   04064 NF-kappa B signaling pathway
    100995010 (PLCG1)
   04066 HIF-1 signaling pathway
    100995010 (PLCG1)
   04020 Calcium signaling pathway
    100995010 (PLCG1)
   04070 Phosphatidylinositol signaling system
    100995010 (PLCG1)
 Organismal Systems
  Immune system
   04650 Natural killer cell mediated cytotoxicity
    100995010 (PLCG1)
   04660 T cell receptor signaling pathway
    100995010 (PLCG1)
   04664 Fc epsilon RI signaling pathway
    100995010 (PLCG1)
   04666 Fc gamma R-mediated phagocytosis
    100995010 (PLCG1)
   04670 Leukocyte transendothelial migration
    100995010 (PLCG1)
  Endocrine system
   04919 Thyroid hormone signaling pathway
    100995010 (PLCG1)
  Nervous system
   04722 Neurotrophin signaling pathway
    100995010 (PLCG1)
  Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    100995010 (PLCG1)
 Human Diseases
  Cancers
   05200 Pathways in cancer
    100995010 (PLCG1)
   05231 Choline metabolism in cancer
    100995010 (PLCG1)
   05206 MicroRNAs in cancer
    100995010 (PLCG1)
   05205 Proteoglycans in cancer
    100995010 (PLCG1)
   05214 Glioma
    100995010 (PLCG1)
   05223 Non-small cell lung cancer
    100995010 (PLCG1)
  Infectious diseases
   05169 Epstein-Barr virus infection
    100995010 (PLCG1)
Enzymes [BR:pps01000]
 3. Hydrolases
  3.1  Acting on ester bonds
   3.1.4  Phosphoric-diester hydrolases
    3.1.4.11  phosphoinositide phospholipase C
     100995010 (PLCG1)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif Motif
Other DBs
NCBI-GI: 
NCBI-GeneID: 
Position
Un
AA seq 1218 aa AA seqDB search
MEFRLKTLSLQATSEDEVNMWIKGLTWLMEDTLQAPTPLQIERWLRKQFYSVDRNREDRI
SAKDLKNMLSQVNYRVPNMRFLRERLTDLEQRSGDITYGQFAQLYRSLMYSAQKTMDLPF
LEASTLRAGERPELCRVSLPEFQQFLLDYQGELWAVDRLQVQEFMLSFLRDPLREIEEPY
FFLDEFVTFLFSKENSVWNSQLDAVCPDTMNNPLSHYWISSSHNTYLTGDQFSSESSLEA
YARCLRMGCRCIELDCWDGPDGMPVIYHGHTLTTKIKFSDVLHTIKEHAFVASEYPVILS
IEDHCSIAQQRNMAQYFKKVLGDTLLTKPVEISADGLPSPNQLKRKILIKHKKLAEGSAY
EEVPTSMMYSENDISNSIKNGILYLEDPVNHEWYPHYFVLTSSKIYYSEETSSDQGNEDE
EEPKEVSSSTELHSNEKWFHGKLGAGRDGRHIAERLLTEYCIETGAPDGSFLVRESETFV
GDYTLSFWRNGKVQHCRIHSRQDAGTPKFFLTDNLVFDSLYDLITHYQQVPLRCNEFEMR
LSEPVPQTNAHESKEWYHASLTRAQAEHMLMRVPRDGAFLVRKRNEPNSYAISFRAEGKI
KHCRVQQEGQTVMLGNSEFDSLVDLISYYEKHPLYRKMKLRYPINEEALEKIGTAEPDYG
ALYEGRNPGFYVEANPMPTFKCAVKALFDYKAQREDELTFTKSAIIQNVEKQEGGWWRGD
YGGKKQLWFPSNYVEEMVNPVALEPEREHLDENSPLGDLLRGVLDVPACQIAIRPEGKNN
RLFVFSISMASVAHWSLDVAADSQEELQDWVKKIREVAQTADARLTEGKIMERRKKIALE
LSELVVYCRPVPFDEEKIGTERACYRDMSSFPETKAEKYVNKAKGKKFLQYNRLQLSRIY
PKGQRLDSSNYDPLPMWICGSQLVALNFQTPDKPMQMNQALFMTGRHCGYVLQPSTMRDE
AFDPFDKSSLRGLEPCAISIEVLGARHLPKNGRGIVCPFVEIEVAGAEYDSTKQKTEFVG
QSVFPVILLILLGHCKPLPTSHPILSQGDLKPFVVAFTVDNGLNPVWPAKPFHFQISNPE
FAFLRFVVYEEDMFSDQNFLAQATFPVKGLKTGYRAVPLKNNYSEDLELASLLIKIDIFP
AKQENGDLSPFSGTSLRERGSDAAGQLFHGRAREGSFESRYQQPFEDFRISQEHLADHFD
SRERRAPRRTRVNGDNRL
NT seq 3657 nt NT seq  +upstreamnt  +downstreamnt
atggaatttcgcctgaaaacgctgagcctgcaagccacatctgaggatgaagtgaacatg
tggatcaagggcttaacttggctgatggaggatacattgcaggcacccacacccctgcag
attgagaggtggctccggaagcagttttactcagtggatcggaatcgtgaggatcgtata
tcagccaaggacctgaagaacatgctgtcccaggtcaactaccgggtccccaacatgcgc
ttcctccgagagcggctgacggacctggagcagcgcagcggggacatcacctacgggcag
tttgctcaactgtaccgcagcctcatgtacagcgcccagaagacgatggacctccccttc
ttggaagccagtactctgagggctggggagcggccggagctttgccgagtgtcccttcct
gagttccagcagttccttcttgactaccagggggagctgtgggctgttgatcgcctccag
gtgcaggagttcatgctcagcttcctccgagaccccttacgagagatcgaggagccatac
ttcttcctggatgagtttgtcactttcctgttctccaaagagaacagtgtgtggaactcg
cagctggatgcagtatgcccggacaccatgaacaaccctctttcccactactggatctcc
tcctcgcacaacacgtacctgaccggggaccagttctccagtgagtcctccttggaagcc
tatgctcgctgcctgcggatgggctgtcgctgcattgagttggactgctgggacggcccg
gatgggatgccagttatttaccatgggcacacccttaccaccaagatcaagttctcagat
gtcctgcacaccatcaaggagcatgcctttgtggcctcagagtacccagtcatcctgtcc
attgaggaccactgcagcattgcccagcagaggaacatggcccaatacttcaagaaggtg
ctgggggacacactcctcaccaagcccgtggagatctctgccgacgggctcccctcaccc
aaccagcttaagaggaagatcctcatcaagcacaagaagctggctgagggcagtgcctac
gaggaggtgcctacatccatgatgtactctgagaacgacatcagcaactctatcaagaat
ggcatcctctacctggaggaccctgtgaaccacgaatggtatccccactactttgttctg
accagcagcaagatctactactctgaggagaccagcagtgaccagggcaacgaggatgag
gaggagcccaaggaggtcagcagcagcacagagctgcactccaatgagaagtggttccat
gggaagctaggggcagggcgtgacgggcgtcacatcgctgagcgcctgcttactgagtac
tgcatcgagaccggagcccctgacggctccttcctcgtgcgagagagtgagaccttcgtg
ggcgactacacgctctctttctggcggaacgggaaagtccagcactgccgtatccactcc
cggcaagatgctgggacccccaagttcttcttgacagacaacctcgtctttgactccctc
tatgacctcatcacgcactaccagcaggtgcccctgcgctgtaatgagtttgagatgcga
ctttcagagcctgtcccacagaccaacgcccacgagagcaaagagtggtaccacgcaagc
ctgaccagagcacaggctgagcacatgctaatgcgcgtccctcgtgatggggccttcctg
gtgcggaagcggaatgagcccaactcatatgccatctctttccgggctgagggcaagatc
aagcattgccgtgtccagcaagagggccagacagtgatgctagggaactcggagttcgac
agccttgttgacctcatcagctactatgagaaacacccgctataccgcaagatgaagctg
cgctatcccatcaacgaggaggcactggagaagattggcacagctgagcctgactacggg
gccctgtatgagggacgcaaccctggcttctatgtagaggcaaaccctatgccaactttc
aagtgtgcagtcaaagccctctttgactacaaggcccagagggaggacgagctgaccttc
accaagagcgccatcatccagaatgtggagaagcaagagggaggctggtggcgaggggac
tacggagggaagaagcagctgtggttcccatcaaactacgtggaagagatggtcaacccc
gtggccctggagccggagagggagcacttggacgagaacagccccctaggggacttgcta
cggggggtcttggatgtgccggcttgtcagattgccatccgtcctgagggcaagaacaac
cggctcttcgtcttctccatcagcatggcgtcggtggcccactggtccctggatgttgct
gccgactcacaggaggagctgcaggactgggtgaaaaagatccgtgaagtggcccagaca
gcagacgccaggctcactgaagggaagataatggaacggaggaagaagattgccctggag
ctctctgaacttgtcgtctactgccggcctgttcccttcgatgaagagaagattggcaca
gaacgtgcttgctaccgggacatgtcatccttcccggaaaccaaggctgagaaatacgtg
aacaaggccaaaggcaagaagttccttcagtacaatcgactgcagctctcccgcatctac
cccaagggccagcgactggattcctccaactacgatcctttgcccatgtggatctgtggc
agtcagcttgtggccctcaacttccagacccctgacaagcctatgcagatgaaccaggcc
ctcttcatgacgggcaggcactgtggctacgtgctgcagccaagcaccatgcgggatgag
gccttcgacccctttgacaagagcagcctccgcgggctggagccatgtgccatctctatt
gaggtgctgggggcccgacatctgccaaagaatggccgaggcattgtgtgtccttttgtg
gagattgaggtggctggagctgagtatgacagcaccaagcagaagacagagtttgtgggt
cagtctgtcttcccagtcatcctcctcatcctgctggggcactgcaagcctctccccacc
agtcatcccatcctctcccagggtgacctgaagccttttgtcgttgccttcacagtggac
aatggactcaaccctgtatggccagccaagcccttccacttccagatcagtaaccctgaa
tttgcctttctgcgcttcgtggtgtatgaggaagacatgtttagtgaccagaatttcctg
gctcaggctactttcccagtaaaaggcctgaagacaggatacagagcagtgcctttgaag
aataactacagtgaggacctggagttggcctccctgctgatcaagattgacattttccct
gccaagcaggagaatggtgacctcagtcccttcagtggtacgtccctgcgggagcggggc
tcagatgccgcaggccagctgtttcacggccgagcccgggaaggctcctttgaatcccgc
taccagcagccgtttgaggacttccgcatctcccaggagcatctcgcagaccattttgac
agtcgagaacgaagggccccaagaaggactcgggtcaatggagacaaccgcctctag

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