KEGG   Prosthecochloris sp. GSB1: CHL67_00920
Entry
CHL67_00920       CDS       T04996                                 
Symbol
leuA
Name
(GenBank) 2-isopropylmalate synthase
  KO
K01649  2-isopropylmalate synthase [EC:2.3.3.13]
Organism
pros  Prosthecochloris sp. GSB1
Pathway
pros00290  Valine, leucine and isoleucine biosynthesis
pros00620  Pyruvate metabolism
pros01100  Metabolic pathways
pros01110  Biosynthesis of secondary metabolites
pros01210  2-Oxocarboxylic acid metabolism
pros01230  Biosynthesis of amino acids
Module
pros_M00432  Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
Brite
KEGG Orthology (KO) [BR:pros00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00620 Pyruvate metabolism
    CHL67_00920 (leuA)
  09105 Amino acid metabolism
   00290 Valine, leucine and isoleucine biosynthesis
    CHL67_00920 (leuA)
Enzymes [BR:pros01000]
 2. Transferases
  2.3  Acyltransferases
   2.3.3  Acyl groups converted into alkyl groups on transfer
    2.3.3.13  2-isopropylmalate synthase
     CHL67_00920 (leuA)
SSDB
Motif
Pfam: HMGL-like LeuA_dimer
Other DBs
NCBI-ProteinID: ASQ89673
UniProt: A0A222SFB5
Position
184378..186060
AA seq 560 aa
MGVMDSSRYAAYPAVEIAERTWPDKRIDAAPVWCSIDLRDGNQALPVPMSVEEKIEMFRL
LVDIGFREIEVGFPSASAVEYRFVRKLIEEDMIPDGVTIQVLTQAREHLIRRTFESLEGV
RNAVVHLYNSTSTVQRDVVFGKSRGEIRDIAVQGTKLVRELRDASGNRGIRFQYSPESFT
GTELDYALDVCHAVMDAWGASATEKIIINLPSTVEMSTPNIFADRIEWFCRTIRQRDAVI
ISVHTHNDRGTAVASAELAVMAGADRVEGALFGNGERSGNLDIVTMALNLHTQGVDPGLD
LSGLSRISEVYSNCTRMTVHSRHPYAGELVYTAFSGSHQDAINKGMKAYETSRNALWNVP
YLPIDPKDVGCSYTAIVRINSQSGKGGIAYVLESAFGYQIPKWMQPDFGAVVQALVDENG
RELLPREIHDSFHREYVRAQVGPFVLRRCHISWEDEEPPAGDQESTLITATLVREGRELP
FSAKGNGPVDAFVKGLGTQTGLRFSVDEYAEHAIGHTADSEAVAYVRIETPEGRKSIGAG
IDSNISLASIKAVLSAVNRL
NT seq 1683 nt   +upstreamnt  +downstreamnt
atgggagtgatggacagcagcaggtatgcagcctatcccgcagtggagatagcggaaagg
acctggccggacaagaggatcgatgctgcgccggtctggtgcagcatcgatttgagggac
ggtaaccaggcgcttccggttccgatgagcgtggaggagaagatcgagatgttcaggctg
cttgtcgatatcggttttcgggaaatagaggtcggttttccttccgcttcggccgtcgag
taccggtttgtcagaaagctcatcgaagaggacatgataccggacggtgtgaccatacag
gtgctgacccaggctcgggagcatctcataaggcgcacgttcgaatcgctggaaggcgtc
cgcaacgccgtcgtccacctctataattcaacgtcgaccgtgcagcgcgacgtggtgttc
ggaaagagccggggcgagatcagggatatcgccgtccagggaacgaaactcgtcagggaa
ctgcgggatgcgtcgggcaatcggggaatacggtttcaatacagcccggaaagcttcact
ggcactgaactcgattacgccctcgatgtctgtcatgccgtgatggatgcatggggcgcg
tcggcgacggaaaaaatcattatcaacctgccgtctacggtcgagatgtcgacaccgaac
atttttgccgacaggatagagtggttttgccgcactattcggcaacgcgacgcggtcatt
atcagcgttcatactcataacgaccggggaacggccgtagcgtcggccgaactcgctgtc
atggcgggcgctgaccgagtcgaaggcgcgctgttcggcaacggagagcgttcaggcaac
ctcgatatcgtcacgatggcgctcaacctccatacgcagggagttgatccgggactcgat
ctttccggcctttcccgcatcagcgaggtctacagcaactgtacgcgcatgaccgtccat
tcacgccatccttatgcgggagaactcgtttacacagcgttttcagggtcgcatcaggat
gccatcaacaagggaatgaaagcctacgagacatcgcggaacgcactctggaacgtaccc
tacctgccgatagatccgaaagacgtcggttgctcgtacacggcgatcgtgaggatcaac
agtcagtcgggcaagggaggaatcgcctacgtgctggagtctgcattcggttatcagatt
cccaaatggatgcaacccgatttcggagcggtcgtgcaggcgctcgtcgacgaaaacggc
agggaactccttccccgcgaaattcatgacagcttccatcgggaatatgtccgggcgcag
gtcggtccgttcgtgctcaggcggtgccatatcagttgggaagacgaagagcctcccgcc
ggtgaccaggaatcgacgctcattaccgctacgcttgtgcgcgaggggcgggaactgcct
ttttcggcgaagggcaacggtcctgtagacgcttttgtcaaggggctggggacgcagacc
ggtttgcgtttcagcgtcgatgagtacgccgagcacgccatcgggcatacggcggattcc
gaggcggtcgcctatgtgcggatcgaaaccccggaaggccgcaagtccattggcgcgggc
atcgattccaacatcagcctcgcgtcgatcaaggctgtgctcagcgctgtcaacagactg
taa

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