KEGG   Pan troglodytes (chimpanzee): 100610515Help
Entry
100610515         CDS       T01005                                 

Gene name
HDAC6
Definition
(RefSeq) histone deacetylase 6 isoform X1
  KO
K11407  histone deacetylase 6 [EC:3.5.1.98]
Organism
ptr  Pan troglodytes (chimpanzee)
Pathway
ptr05034  Alcoholism
ptr05165  Human papillomavirus infection
ptr05203  Viral carcinogenesis
Brite
KEGG Orthology (KO) [BR:ptr00001]
 Human Diseases
  Cancers
   05203 Viral carcinogenesis
    100610515 (HDAC6)
  Substance dependence
   05034 Alcoholism
    100610515 (HDAC6)
  Infectious diseases
   05165 Human papillomavirus infection
    100610515 (HDAC6)
Enzymes [BR:ptr01000]
 3. Hydrolases
  3.5  Acting on carbon-nitrogen bonds, other than peptide bonds
   3.5.1  In linear amides
    3.5.1.98  histone deacetylase
     100610515 (HDAC6)
Protein phosphatases and associated proteins [BR:ptr01009]
 Protein Ser/ Thr phosphatases
  Phosphoprotein phosphatases (PPPs)
   Protein phosphatase-1
    PP1-interacting proteins (PIPs)
     100610515 (HDAC6)
Messenger RNA biogenesis [BR:ptr03019]
 Eukaryotic Type
  mRNA surveillance and transport factors
   mRNA cycle factors
    Stress granule specific factors
     100610515 (HDAC6)
Membrane trafficking [BR:ptr04131]
 Autophagy
  Aggrephagy
   Other aggrephagy associated proteins
    100610515 (HDAC6)
Chromosome and associated proteins [BR:ptr03036]
 Eukaryotic Type
  Histone modification proteins
   HDACs (histone deacetylases)
    Class II HDACs
     100610515 (HDAC6)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif
Pfam: Hist_deacetyl zf-UBP
Motif
Other DBs
NCBI-GeneID: 100610515
NCBI-ProteinID: XP_024209112
Position
X
AA seq 1287 aa AA seqDB search
MEKKSLSARVPTGRQKLGGASQGRSLRKGLRPMSGAASTARRRRRREGGGGRPKAARDWL
KTNRGRGQASSTMTSTGQDSTTTRQRRSRQNPQSPPQDSSVTSKRNIKKGAVPRSIPNLA
EVKKKGKMKKLGQAMEEDLIVGLQGMELNLEAEALAGTGLVLDEQLNEFHCLWDDSFPEG
PERLHAIKEQLIQEGLLDRCVSFQARFAEKEELMLVHSLEYIDLMETTQYMNEGELRVLA
DTYDSVYLHPNSYSCACLASGSVLRLVDAVLGAEIRNGMAIIRPPGHHAQHSLMDGYCMF
NHVAVAARYAQQKHRIRRVLIVDWDVHHGQGTQFTFDQDPSVLYFSIHRYEQGRFWPHLK
ASNWSTTGFGQGQGYTINVPWNQVGMRDADYIAAFLHVLLPVALEFQPQLVLVAAGFDAL
QGDPKGEMAATPAGFAQLTHLLMGLAGGKLILSLEGGYNLRALAEGVSASLHTLLGDPCP
MLESPGAPCRSAQASVSCALEALEPFWEVLVRSTETVERDNMEEDNVEESEEEGPWEPPV
LPILTWPVLQSRTGLVYDQNMMNHCNLWDSHHPEVPQRILRIMCRLEELGLAGRCLTLTP
RPATEAELLTCHSAEYVGHLRATEKMKTRELHRESSNFDSIYICPSTFACAQLATGAACR
LVEAVLSGEVLNGAAVVRPPGHHAEQDAACGFCFFNSVAVAARHAQAISGHALRILIVDW
DVHHGNGTQHMFEDDPSVLYVSLHRYDHGTFFPMGDEGASSQIGRAAGTGFTVNVAWNGP
RMGDADYLAAWHRLVLPIAYEFNPELVLVSAGFDAARGDPLGGCQVSPEGYAHLTHLLMG
LASGRIILILEGGYNLTSISESMAACTRSLLGDPPPLLTLPRPPLSGALASITETIQVHR
RYWRSLRVMKVEDREGPSSSKLVTKKAPQPAKPRLAERMTTREKKVLEAGMGKVTSASFG
EESTPGQTKSETAVVALTQDQPSEAATGGATLAQTISEAAIGGAMLGQTTSEEAVGGATP
DQTTSEETVGGAILDQTTSEDAVGGATLGQTTSEEAVGGATLAQTTSEAAMEGATLDQTT
SEEAPGGTELIQTPLASSTDHQTTPTSPVQGTTPQISPSTLIGSLRTLELGSESQGASES
QAPGEENLLGEAAGGQDMADSMLMQGSRGLTDQAIFYAVTPLPWCPHLVAVCPIPAAGLD
VTQPCGDCGTIQENWVCLSCYQVYCGRYINGHMLQHHGNSGHPLVLSYIDLSAWCYYCQA
YVHHQALLDVKNIAHQNKFGEDMPHPH
NT seq 3864 nt NT seq  +upstreamnt  +downstreamnt
atggaaaagaaaagcctgagcgctcgcgtccccacaggtcgccagaaacttggcggagcg
agccaagggcggagtttgagaaaggggctgcgtccaatgagtggagcggcgagtacagcg
cgtcgacggcggaggcgggaagggggcggaggccgaccgaaggcggctagggactggctg
aagacgaaccgcggcaggggccaagcctcctcaactatgacctcaaccggccaggattcc
accacaaccaggcagcgaagaagtaggcagaacccccagtcgccccctcaggactccagt
gtcacttcgaagcgaaatattaaaaagggagccgttccccgctctatccccaatctagcg
gaggtaaagaagaaaggcaaaatgaagaagctcggccaagcaatggaagaagacctaatc
gtgggactgcaagggatggagctgaaccttgaggctgaagcactggctggcactggcttg
gtgttggatgagcagctaaatgaattccattgcctctgggatgacagcttcccggaaggc
cctgagcggctccatgccatcaaggagcaactgatccaggagggcctcctagatcgctgc
gtgtcctttcaggcccggtttgctgaaaaggaagagctgatgttggttcacagcctagaa
tatattgatctgatggaaacaacccagtacatgaatgagggagaactccgtgtcctagca
gacacctacgactcagtttatctgcatccgaactcatactcctgtgcctgcctggcctca
ggctctgtcctcaggctggtggatgcggtcctgggggctgagatccggaatggcatggcc
atcattaggcctcctggacatcacgcccagcacagtcttatggatggctattgcatgttc
aaccacgtggctgtggcagcccgctatgctcaacagaaacaccgcatccggagggtcctt
atcgtagattgggatgtgcaccacggtcaaggaacacagttcaccttcgaccaggacccc
agtgtcctctatttctccatccaccgctacgagcagggtaggttctggccccacctgaag
gcctctaactggtccaccacaggtttcggccaaggccaaggatataccatcaatgtgcct
tggaaccaggtggggatgcgggatgctgactacattgctgctttcctgcacgtcctgctg
ccagtcgccctcgagttccagcctcagctggtcctggtggctgctggatttgatgccctg
caaggggaccccaagggtgagatggccgccactccggcagggttcgcccaactaacccac
ctgctcatgggtctggcaggaggcaagctgatcctgtctctggagggtggctacaacctc
cgcgccctggctgaaggcgtcagtgcttcgctccacacccttctgggagacccttgcccc
atgctggagtcacctggtgccccctgccggagtgcccaggcttcagtttcctgtgctctg
gaagcccttgagcccttctgggaggttcttgtgagatcaactgagaccgtggagagggac
aacatggaggaggacaatgtagaggagagcgaggaggaaggaccctgggagccccctgtg
ctcccaatcctgacatggccagtgctacagtctcgcacagggctggtctatgaccaaaat
atgatgaatcactgcaacttgtgggacagccaccaccctgaggtaccccagcgcatcttg
cggatcatgtgccgtctggaggagctgggccttgccgggcgctgcctcaccctgacaccg
cgccctgccacagaggctgagctgctcacctgtcacagtgctgagtacgtgggtcatctc
cgggccacagagaaaatgaaaacccgggagctgcaccgtgagagttccaactttgactcc
atctatatctgccccagtaccttcgcctgtgcacagcttgccactggcgctgcctgccgc
ctggtggaggctgtgctctcaggagaggttctgaatggtgctgctgtggtgcgtccccca
ggacaccacgcagagcaggatgcagcttgcggtttttgctttttcaactctgtggctgtg
gctgctcgccatgcccaggctatcagtgggcatgccctacggatcctgattgtggattgg
gatgtccaccacggtaatggaactcagcacatgtttgaggatgaccccagtgtgctatat
gtgtccctgcaccgctatgatcatggcaccttcttccccatgggggatgagggtgccagc
agccagatcggccgggctgcgggcacaggcttcaccgtcaacgtggcatggaacgggccc
cgcatgggtgacgctgactacctagctgcctggcatcgcctggtgcttcccattgcctac
gagtttaacccagaactggtgctggtctcagctggctttgatgctgcacggggggacccg
ctggggggctgccaggtgtcacctgagggttatgcccacctcacccacctgctgatgggc
cttgccagtggccgcattatccttatcctagagggtggctataacctgacatccatctca
gagtccatggctgcctgcactcgctccctccttggagacccaccacccctgctgaccctg
ccacggcccccactatcaggggccctggcctcaatcactgagaccatccaagtccatcgc
agatactggcgcagcttacgggtcatgaaggtagaagacagagaaggaccctccagttct
aagttggtcaccaagaaggcaccccaaccagccaaacctaggttagctgagcggatgacc
acacgagaaaagaaggttctggaagcaggcatggggaaagtcacctcggcatcatttggg
gaagagtccactccaggccagactaagtcagagacagctgtggtggccctcactcaggac
cagccctcagaggcagccacagggggagccactctggcccagaccatttctgaggcagcc
attgggggagccatgctgggccagaccacctcagaggaggctgtcgggggagccactccg
gaccagaccacctcagaggagactgtgggaggagccattctggaccagaccacctcagag
gatgctgttgggggagccacgctgggccagactacctcagaggaggctgtaggaggagct
acactggcccagaccacctcggaggcagccatggagggagccacactggaccagactacg
tcagaggaggctccagggggcaccgagctgatccaaactcctctagcctcgagcacagac
caccagaccaccccaacctcacctgtgcagggaactacaccccagatatctcccagtaca
ctgattgggagtctcaggaccttggagctaggcagcgaatctcagggggcctcagaatct
caggccccaggagaggagaacctactaggagaggcagctggaggtcaggacatggctgat
tcgatgctgatgcagggatctaggggcctcactgatcaggccatattttatgctgtgaca
ccactgccctggtgtccccatttggtggcagtatgccccatacctgcagcaggcctagac
gtgacccaaccttgtggggactgtggaacaatccaagagaattgggtgtgtctctcttgc
tatcaggtctactgtggtcgttacatcaatggccacatgctccaacaccatggaaattct
ggacacccgctggtcctcagctacatcgacctgtcagcctggtgttactactgtcaggcc
tatgtccaccaccaggctctcctagatgtgaagaacatcgcccaccagaacaagtttggg
gaggatatgccccacccacactaa

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