KEGG   Pan troglodytes (chimpanzee): 450161Help
Entry
450161            CDS       T01005                                 

Gene name
MAPK14, CSBP1, SAPK2a
Definition
mitogen-activated protein kinase 14 (EC:2.7.11.24)
Orthology
K04441  
p38 MAP kinase [EC:2.7.11.24]
Organism
ptr  Pan troglodytes (chimpanzee)
Pathway
MAPK signaling pathway
Rap1 signaling pathway
FoxO signaling pathway
Adrenergic signaling in cardiomyocytes
VEGF signaling pathway
Osteoclast differentiation
Platelet activation
Toll-like receptor signaling pathway
NOD-like receptor signaling pathway
RIG-I-like receptor signaling pathway
T cell receptor signaling pathway
Fc epsilon RI signaling pathway
TNF signaling pathway
Leukocyte transendothelial migration
Neurotrophin signaling pathway
Retrograde endocannabinoid signaling
Dopaminergic synapse
Inflammatory mediator regulation of TRP channels
GnRH signaling pathway
Progesterone-mediated oocyte maturation
Prolactin signaling pathway
Amyotrophic lateral sclerosis (ALS)
Salmonella infection
Pertussis
Leishmaniasis
Chagas disease (American trypanosomiasis)
Toxoplasmosis
Tuberculosis
Hepatitis C
Influenza A
Epstein-Barr virus infection
Proteoglycans in cancer
Brite
KEGG Orthology (KO) [BR:ptr00001]
 Environmental Information Processing
  Signal transduction
   04015 Rap1 signaling pathway
    450161 (MAPK14)
   04010 MAPK signaling pathway
    450161 (MAPK14)
   04370 VEGF signaling pathway
    450161 (MAPK14)
   04668 TNF signaling pathway
    450161 (MAPK14)
   04068 FoxO signaling pathway
    450161 (MAPK14)
 Organismal Systems
  Immune system
   04611 Platelet activation
    450161 (MAPK14)
   04620 Toll-like receptor signaling pathway
    450161 (MAPK14)
   04621 NOD-like receptor signaling pathway
    450161 (MAPK14)
   04622 RIG-I-like receptor signaling pathway
    450161 (MAPK14)
   04660 T cell receptor signaling pathway
    450161 (MAPK14)
   04664 Fc epsilon RI signaling pathway
    450161 (MAPK14)
   04670 Leukocyte transendothelial migration
    450161 (MAPK14)
  Endocrine system
   04912 GnRH signaling pathway
    450161 (MAPK14)
   04914 Progesterone-mediated oocyte maturation
    450161 (MAPK14)
   04917 Prolactin signaling pathway
    450161 (MAPK14)
  Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    450161 (MAPK14)
  Nervous system
   04728 Dopaminergic synapse
    450161 (MAPK14)
   04723 Retrograde endocannabinoid signaling
    450161 (MAPK14)
   04722 Neurotrophin signaling pathway
    450161 (MAPK14)
  Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    450161 (MAPK14)
  Development
   04380 Osteoclast differentiation
    450161 (MAPK14)
 Human Diseases
  Cancers
   05205 Proteoglycans in cancer
    450161 (MAPK14)
  Neurodegenerative diseases
   05014 Amyotrophic lateral sclerosis (ALS)
    450161 (MAPK14)
  Infectious diseases
   05132 Salmonella infection
    450161 (MAPK14)
   05133 Pertussis
    450161 (MAPK14)
   05152 Tuberculosis
    450161 (MAPK14)
   05164 Influenza A
    450161 (MAPK14)
   05160 Hepatitis C
    450161 (MAPK14)
   05169 Epstein-Barr virus infection
    450161 (MAPK14)
   05145 Toxoplasmosis
    450161 (MAPK14)
   05140 Leishmaniasis
    450161 (MAPK14)
   05142 Chagas disease (American trypanosomiasis)
    450161 (MAPK14)
Enzymes [BR:ptr01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.24  mitogen-activated protein kinase
     450161 (MAPK14)
Protein kinases [BR:ptr01001]
 Serine/threonine protein kinases: CMGC group
  MAPK family [OT]
   450161 (MAPK14)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif Motif
Other DBs
NCBI-GI: 
NCBI-GeneID: 
UniProt: 
Position
6
AA seq 360 aa AA seqDB search
MSQERPTFYRQELNKTIWEVPERYQNLSPVGSGAYGSVCAAFDTKTGLRVAVKKLSRPFQ
SIIHAKRTYRELRLLKHMKHENVIGLLDVFTPARSLEEFNDVYLVTHLMGADLNNIVKCQ
KLTDDHVQFLIYQILRGLKYIHSADIIHRDLKPSNLAVNEDCELKILDFGLARHTDDEMT
GYVATRWYRAPEIMLNWMHYNQTVDIWSVGCIMAELLTGRTLFPGTDHINQLQQIMRLTG
TPPAYLINRMPSHEARNYIQSLTQMPKMNFANVFIGANPLAVDLLEKMLVLDSDKRITAA
QALAHAYFAQYHDPDDEPVADPYDQSFESRDLLIDEWKSLTYDEVISFVPPPLDQEEMES
NT seq 1083 nt NT seq  +upstreamnt  +downstreamnt
atgtctcaggagaggcccacgttctaccggcaggagctgaacaagacaatctgggaggtg
cccgagcgttaccagaacctgtctccagtgggctctggcgcctatggctctgtgtgtgct
gcttttgacacaaaaacggggttacgtgtggcagtgaagaagctctccagaccatttcag
tccatcattcatgcaaaaagaacctacagagaactgcggttacttaaacatatgaaacat
gaaaatgtgattggtctgttggacgtttttacacctgcaaggtctctggaggaattcaat
gatgtgtatctggtgacccatctcatgggggcagatctgaacaacattgtgaaatgtcag
aagcttacagatgaccatgttcagttccttatctaccaaattctccgaggtctaaagtat
atacattcagctgacataattcacagggacctaaaacctagtaatctagctgtgaatgaa
gactgtgagctgaagattctggattttggactggctcggcacacagatgatgaaatgaca
ggctacgtggccactaggtggtacagggctcctgagatcatgctgaactggatgcattac
aaccagacagttgatatttggtcagtgggatgcataatggccgagctgttgactggaaga
acattgtttcctggtacagaccatattaaccagcttcagcagattatgcgtctgacagga
acaccccccgcttatctcattaacaggatgccaagccatgaggcaagaaactatattcag
tctttgactcagatgccaaagatgaactttgcgaatgtatttattggtgccaatccgctg
gctgtcgacttgctggagaagatgcttgtattggactcagataagagaattacagcggcc
caagcccttgcacatgcctactttgctcagtaccacgatcctgatgatgaaccagtggcc
gatccttatgatcagtcctttgaaagcagggacctccttatagatgagtggaaaagcctg
acctatgatgaagtcatcagctttgtgccaccaccccttgaccaagaagagatggagtcc
tga

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