KEGG   Pan troglodytes (chimpanzee): 450909Help
Entry
450909            CDS       T01005                                 

Gene name
CYP2C8
Definition
cytochrome P450, family 2, subfamily C, polypeptide 8
Orthology
K17718  
cytochrome P450, family 2, subfamily C, polypeptide 8 [EC:1.14.14.1]
Organism
ptr  Pan troglodytes (chimpanzee)
Pathway
Arachidonic acid metabolism
Linoleic acid metabolism
Retinol metabolism
Drug metabolism - cytochrome P450
Metabolic pathways
Serotonergic synapse
Chemical carcinogenesis
Brite
KEGG Orthology (KO) [BR:ptr00001]
 Metabolism
  Lipid metabolism
   00590 Arachidonic acid metabolism
    450909 (CYP2C8)
   00591 Linoleic acid metabolism
    450909 (CYP2C8)
  Metabolism of cofactors and vitamins
   00830 Retinol metabolism
    450909 (CYP2C8)
  Xenobiotics biodegradation and metabolism
   00982 Drug metabolism - cytochrome P450
    450909 (CYP2C8)
 Organismal Systems
  Nervous system
   04726 Serotonergic synapse
    450909 (CYP2C8)
 Human Diseases
  Cancers
   05204 Chemical carcinogenesis
    450909 (CYP2C8)
Enzymes [BR:ptr01000]
 1. Oxidoreductases
  1.14  Acting on paired donors with incorporation of molecular oxygen
   1.14.14  With reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen into the other donor
    1.14.14.1  unspecific monooxygenase
     450909 (CYP2C8)
Cytochrome P450 [BR:ptr00199]
 Cytochrome P450, animal type
  CYP2 family
   450909 (CYP2C8)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif
Pfam: 
Motif
Other DBs
NCBI-GI: 
NCBI-GeneID: 
Ensembl: 
UniProt: 
Position
10
AA seq 420 aa AA seqDB search
MNPIVVLHGYEAVKEALIDNGEEFSGRGSSPISQRITKGLGIISSNGKRWKEIRRFSLTT
LRNFGMGKRSIEDRVQEEAHCLVEELRKTKASPCDPTFILGCAPCNVICSVVFQKRFDYK
DQNFLTLMKRFNENFRILNSPWIQVCNNFPLLIDCFPGTHNKVLTNVALTQSYIREKVKE
HQASLDVNNPRDFIDCFLIKMEQEKDNQKSEFNIENLVGTVADLFVAGTETTSTTLRYGL
LLLLMHPEVTAKVQEEIDHVIGRHRTPCMQDRSHMPYTDAVVHEIQRYSDLVPTGVPHAV
TTDTKFRNYLIPKGTTIMTLLTSVLHDDKEFPNPNIFDPGHFLDKNGNFKKSDYFMPFSA
GKRICAGEGLARMELFLFLTTILQNFNLKSVDDLKNLNTTAVTKGIVSLPPSYQICFIPV
NT seq 1263 nt NT seq  +upstreamnt  +downstreamnt
atgaatcccatagtggtgttgcatggatatgaggcagtgaaggaagccctgattgataat
ggagaggagttttctggaagaggcagttccccaatatctcaaagaattactaaaggactt
ggaatcatttccagcaatggaaagagatggaaggagatccggcgtttctccctcacaacc
ttgcggaattttgggatggggaagaggagcattgaggaccgtgttcaagaggaagctcac
tgccttgtggaggagttaagaaaaaccaaggcctcaccctgtgatcccactttcatcctg
ggctgcgctccctgcaatgtgatctgctccgttgttttccagaaacgatttgattataaa
gatcagaattttctcaccctgatgaaaagattcaatgaaaacttcaggattctgaactcc
ccatggatccaggtctgcaataatttccctctactcattgattgtttcccaggaactcac
aacaaagtgcttacaaatgttgctcttacacaaagttacattagggagaaagtaaaagaa
caccaagcatcactggatgttaacaatcctcgggactttatcgattgcttcctgatcaaa
atggagcaggaaaaggacaaccaaaagtcagaattcaatattgaaaacttggttggcact
gtagctgatctatttgttgctggaacagagacaacaagcaccactctgagatatggactc
ctgctcctgctgatgcacccggaggtcacagctaaagtccaggaagagattgatcatgta
attggcagacacaggaccccctgcatgcaggataggagccacatgccttacactgatgct
gtagtgcacgagatccagagatacagtgaccttgtccccaccggtgtgccccatgcagtg
accactgatactaagttcagaaactacctcatccccaagggcacaaccataatgacatta
ctgacttccgtgctacacgatgacaaagaatttcctaatccaaatatctttgaccctggc
cactttctagataagaatggcaactttaagaaaagtgactacttcatgcctttctcagca
ggaaaacgaatttgtgcaggagaaggacttgcccgcatggagctatttttatttctaacc
acaattttacagaactttaacctgaaatctgttgatgatttaaagaacctcaatactact
gcagttaccaaagggattgtttctctgccaccctcgtaccagatctgcttcatccctgtc
tga

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