KEGG   Pan troglodytes (chimpanzee): 452897Help
Entry
452897            CDS       T01005                                 

Gene name
SOS2
Definition
son of sevenless homolog 2 (Drosophila)
Orthology
K03099  
son of sevenless
Organism
ptr  Pan troglodytes (chimpanzee)
Pathway
MAPK signaling pathway
ErbB signaling pathway
Ras signaling pathway
Chemokine signaling pathway
FoxO signaling pathway
PI3K-Akt signaling pathway
Dorso-ventral axis formation
Focal adhesion
Gap junction
Jak-STAT signaling pathway
Natural killer cell mediated cytotoxicity
T cell receptor signaling pathway
B cell receptor signaling pathway
Fc epsilon RI signaling pathway
Neurotrophin signaling pathway
Regulation of actin cytoskeleton
Insulin signaling pathway
GnRH signaling pathway
Estrogen signaling pathway
Prolactin signaling pathway
Alcoholism
Hepatitis C
Pathways in cancer
Proteoglycans in cancer
MicroRNAs in cancer
Renal cell carcinoma
Endometrial cancer
Glioma
Prostate cancer
Chronic myeloid leukemia
Acute myeloid leukemia
Non-small cell lung cancer
Brite
KEGG Orthology (KO) [BR:ptr00001]
 Environmental Information Processing
  Signal transduction
   04014 Ras signaling pathway
    452897 (SOS2)
   04010 MAPK signaling pathway
    452897 (SOS2)
   04012 ErbB signaling pathway
    452897 (SOS2)
   04630 Jak-STAT signaling pathway
    452897 (SOS2)
   04068 FoxO signaling pathway
    452897 (SOS2)
   04151 PI3K-Akt signaling pathway
    452897 (SOS2)
 Cellular Processes
  Cell motility
   04810 Regulation of actin cytoskeleton
    452897 (SOS2)
  Cellular commiunity
   04510 Focal adhesion
    452897 (SOS2)
   04540 Gap junction
    452897 (SOS2)
 Organismal Systems
  Immune system
   04650 Natural killer cell mediated cytotoxicity
    452897 (SOS2)
   04660 T cell receptor signaling pathway
    452897 (SOS2)
   04662 B cell receptor signaling pathway
    452897 (SOS2)
   04664 Fc epsilon RI signaling pathway
    452897 (SOS2)
   04062 Chemokine signaling pathway
    452897 (SOS2)
  Endocrine system
   04910 Insulin signaling pathway
    452897 (SOS2)
   04912 GnRH signaling pathway
    452897 (SOS2)
   04915 Estrogen signaling pathway
    452897 (SOS2)
   04917 Prolactin signaling pathway
    452897 (SOS2)
  Nervous system
   04722 Neurotrophin signaling pathway
    452897 (SOS2)
  Development
   04320 Dorso-ventral axis formation
    452897 (SOS2)
 Human Diseases
  Cancers
   05200 Pathways in cancer
    452897 (SOS2)
   05206 MicroRNAs in cancer
    452897 (SOS2)
   05205 Proteoglycans in cancer
    452897 (SOS2)
   05214 Glioma
    452897 (SOS2)
   05221 Acute myeloid leukemia
    452897 (SOS2)
   05220 Chronic myeloid leukemia
    452897 (SOS2)
   05211 Renal cell carcinoma
    452897 (SOS2)
   05215 Prostate cancer
    452897 (SOS2)
   05213 Endometrial cancer
    452897 (SOS2)
   05223 Non-small cell lung cancer
    452897 (SOS2)
  Substance dependence
   05034 Alcoholism
    452897 (SOS2)
  Infectious diseases
   05160 Hepatitis C
    452897 (SOS2)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif Motif
Other DBs
NCBI-GI: 
NCBI-GeneID: 
Ensembl: 
UniProt: 
Position
14
AA seq 1301 aa AA seqDB search
MQQAPQPYEFFSEENSPKWRGLLVSALRKVQEQVHPTLSANEESLYYIEELIFQLLNKLC
MAQPRTVQDVEERVQKTFPHPIDKWAIADAQSAIEKRKRRNPLLLPVDKIHPSLKEVLGY
KVDYHVSLYIVAVLEYISADILKLAGNYVFNIRHYEISQQDIKVSMCADKVLMDMFDQDD
IGLVSLCEDEPSSSGELNYYDLVRTEIAEERQYLRELNMIIKVFREAFLSDRKLFKPSDI
EKIFSNISDIHELTVKLLGLIEDTVEMTDESSPHPLAGSCFEDLAEEQAFDPYETLSQDI
LSPEFHEHFNKLMARPAVALHFQSIADGFKEAVRYVLPRLMLVPVYHCWHYFELLKQLKA
CSEEQEDRECLNQAITALMNLQGSMDRIYKQYSPRRRPGEREYVARRCNEFIMHVPLTRI
GAMHERHIFLFDGLMISCKPNHGQTRLPGYSSAEYRLKEKFVMRKIQICDKEDTCEYKHA
FELVSKDENSIIFAAKSAEEKNNWMAALISLHYRSTLDRMLDSVLLKEENEQPLRLPSPE
VYRFVVKDSEENIVFEDNLQSRSGIPIIKGGTVVKLIERLTYHMYADPNFVRTFLTTYRS
FCKPQELLSLLIERFEIPEPEPTDADKLAIEKGEQPISADLKRFRKEYVQPVQLRILNVF
RHWVEHHFYDFERDLELLERLESFISSVRGKAMKKWVESIAKIIRRKKQAQANGISHNIT
FESPPPPIEWHISKPGQFETFDLMTLHPIEIARQLTLLESDLYRKVQPSELVGSVWTKED
KEINSPNLLKMIRHTTNLTLWFEKCIVEAENFEERVAVLSRIIEILQVFQDLNNFNGVLE
IVSAVNSVSVYRLDHTFEALQERKRKILDEAVELSQDHFKKYLVKLKSINPPCVPFFGIY
LTNILKTEEGNNDFLKKKGKDLINFSKRRKVAEITGEIQQYQNQPYCLRIEPDMRRFFEN
LNPMGSASEKEFTDYLFNKSLEIEPRNCKQPPRFPRKSTFSLKSPGIRPNTGRHGSTSGT
LRGHPTPLEREPCKISFSRIAETELESTVSAPTSPNTPSTPPVSASSDLSVFLDVDLNSS
CGSNSIFAPVLLPHSKSFFSSCGSLHKLSEEPLIPPPLPPRKKFDHDASNSKGNMKSDDD
PPAIPPRQPPPPKVKPRVPVPTGAFDGPLHSPPPPPPRDPLPDTPPPVPLRPPEHFINCP
FNLQPPPLGHLHRDSDWLRDISTCPNSPSTPPSTPSPRVPRRCYVLSSSQNNLAHPPAPP
VPPRQNSSPHLPKLPPKTYKRELSHPPLYRLPLLENAETPQ
NT seq 3906 nt NT seq  +upstreamnt  +downstreamnt
atgcagcaggcgccgcagccttacgagttcttcagcgaggagaacagtccgaaatggcgg
ggactgttggtctcggccctgcggaaggttcaggaacaagtgcatcccactctctcagct
aatgaagagtctctctattatattgaagagctgatttttcagctgcttaataaattatgc
atggcccagccaaggactgttcaagatgtagaggagcgagttcagaagacctttcctcac
ccaattgataaatgggccattgctgatgcacaatctgctatagaaaaacgaaaacgaaga
aatcctcttttactgcctgtggacaaaatccatccttcgttgaaggaagtattagggtac
aaagtggactaccatgtgtccctatatattgtggctgtactagagtatatctcagctgat
attttaaaattggctggtaattatgtttttaatatccggcattatgaaatatctcagcag
gacattaaagtgtcaatgtgtgcggataaggttttgatggacatgtttgatcaggatgac
ataggtttggtttctctctgtgaagatgaacctagttcttctggtgaattaaactactat
gatcttgtcagaactgaaatcgcagaagaaagacagtatctacgggaattaaatatgatc
ataaaagtgtttcgagaagcctttctttctgatagaaagctgtttaaaccttctgatatc
gaaaagatttttagtaacatttcagatatacatgaattgactgtgaaacttttaggtttg
attgaagacacagttgaaatgactgatgaaagcagtcctcatcccttagctggcagctgt
tttgaagatttggcagaagagcaagcatttgatccttatgaaacattatcacaggacatt
ctttcaccagagtttcatgaacatttcaataaattaatggccagacctgcagttgctcta
cactttcagtccattgctgatggttttaaagaggcagttcgttatgtccttccacgtctt
atgctggtgccagtgtatcactgttggcactactttgagttactaaagcaattgaaagca
tgtagtgaagaacaagaagacagagaatgtttgaaccaagctattactgctctcatgaat
ctccaaggtagcatggaccgaatttacaagcagtattcacctagacgtcgacctggagaa
cgcgaatatgttgcacggcggtgcaatgaattcattatgcatgtacccttgacaagaatc
ggtgccatgcatgagcggcatatttttctgtttgatggcttaatgatcagttgtaaacct
aatcatggccagactcggcttccaggttacagtagtgcagaatacaggttaaaagaaaaa
tttgtcatgaggaaaatacaaatttgtgataaagaagatacttgtgagtacaagcatgca
tttgaattagtatccaaagatgagaacagcataatatttgctgctaagtctgctgaagaa
aaaaacaactggatggcagcccttatttctcttcattatcgtagtactctagatcgaatg
ttagattcagtattattgaaagaagaaaatgagcaaccactgagattaccaagtcctgaa
gtatatcgttttgtagtaaaagactctgaggaaaacattgtttttgaagacaacttgcaa
agtagaagtggcatccccattattaaaggaggaactgtagtgaaattaattgaaaggtta
acatatcatatgtatgcagatcccaattttgttcgtacttttcttaccacatatcgttca
ttttgtaaaccacaggaattgctgagcttactgattgaacggtttgaaattccagagcca
gaacctactgatgcagacaaattggcaatagagaaaggcgagcagccaatcagtgcagac
cttaaaagatttcgcaaggaatatgtccaaccagtacaacttaggatcttaaatgtattt
cggcattgggttgaacatcatttttatgactttgaaagagacttggaattgcttgaaaga
ctagaatccttcatttcaagtgtaagagggaaagctatgaaaaaatgggtagagtcaatc
gctaagatcatcaggaggaagaagcaagctcaggcaaatggaataagccataatattacc
tttgaaagtccacctccaccaattgaatggcatatcagcaaaccaggacagtttgaaaca
tttgatctcatgacacttcatccaatagaaattgcacgtcagctgacacttttggagtct
gatctctacaggaaagttcaaccgtctgaacttgtagggagtgtgtggaccaaagaagat
aaagaaataaattctccaaatttattaaaaatgattcgccataccacaaatctcaccctc
tggtttgaaaaatgcattgtggaagcagaaaattttgaagaacgggtggcagtactaagt
agaattatagaaattctgcaagtttttcaagatttgaataatttcaatggcgtattggag
atagtcagtgcagtaaattcagtatcagtatacagactagaccatacctttgaggcattg
caggaaagaaaaaggaaaattttggacgaagctgtggaattaagtcaagatcactttaaa
aaatacctagtaaaacttaagtcaatcaatccaccttgtgtgcctttttttggaatatat
ttaacaaatattctgaagaccgaagaagggaataatgattttttaaaaaagaaagggaaa
gatttaatcaatttcagtaagaggaggaaagtagctgaaattactggagaaattcagcag
tatcagaatcagccttactgtttacggatagaaccagatatgaggagattctttgaaaac
cttaacccaatgggaagtgcatctgaaaaagagtttacagattatttgttcaacaagtca
ctagaaattgaacctcgaaactgcaaacagccacctcgatttcctaggaaatcaactttt
tccttaaaatctcctggaataaggcctaacacaggccgacatggctctacctcaggtact
ttacgaggtcacccaacaccattagaaagagaaccatgtaaaataagctttagtcggatt
gctgaaactgagctggaatcaacagtgtcagcaccaacctctccaaatacaccatctact
ccaccagtatctgcttcttcagaccttagtgtatttttagatgtggatctcaacagctcc
tgtggcagcaatagcatcttcgctccagtgcttttgccacattcaaagtctttctttagt
tcatgtggtagtttacataaactaagtgaagagcccctgattcctcctcctcttcctcct
cgaaaaaagtttgatcatgatgcttcaaattccaagggaaatatgaaatctgatgatgat
cctcctgctattccaccgagacagcctcctcctccaaaggtaaaacccagagttcctgtt
cctactggtgcatttgatgggcctctgcatagtccacctccgccaccaccaagagatcct
cttcctgatacccctccaccagttccccttcggcctccagaacactttataaactgtcca
tttaatcttcagccacctccactggggcatcttcacagagattcagactggctcagagac
attagtacgtgtccaaattcgccaagcactcctcctagcacaccctctccaagggtaccg
cgtcgatgctatgtgctcagttctagtcagaataatcttgctcatcctccagctccccct
gttccaccaaggcagaattcaagccctcatctgccaaaactgccaccaaagacttacaaa
cgggagctttcgcaccccccattgtacagactgcctttgctagaaaatgcagaaactccc
caatga

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