KEGG   Pan troglodytes (chimpanzee): 452897Help
Entry
452897            CDS       T01005                                 

Gene name
SOS2
Definition
son of sevenless homolog 2 (Drosophila)
Orthology
K03099  
son of sevenless
Organism
ptr  Pan troglodytes (chimpanzee)
Pathway
MAPK signaling pathway
ErbB signaling pathway
Ras signaling pathway
Chemokine signaling pathway
FoxO signaling pathway
PI3K-Akt signaling pathway
Dorso-ventral axis formation
Focal adhesion
Gap junction
Jak-STAT signaling pathway
Natural killer cell mediated cytotoxicity
T cell receptor signaling pathway
B cell receptor signaling pathway
Fc epsilon RI signaling pathway
Neurotrophin signaling pathway
Regulation of actin cytoskeleton
Insulin signaling pathway
GnRH signaling pathway
Estrogen signaling pathway
Prolactin signaling pathway
Alcoholism
Hepatitis C
Pathways in cancer
Proteoglycans in cancer
MicroRNAs in cancer
Renal cell carcinoma
Endometrial cancer
Glioma
Prostate cancer
Chronic myeloid leukemia
Acute myeloid leukemia
Non-small cell lung cancer
Class
Environmental Information Processing; Signal transduction; Ras signaling pathway [PATH:ptr04014]
Environmental Information Processing; Signal transduction; MAPK signaling pathway [PATH:ptr04010]
Environmental Information Processing; Signal transduction; ErbB signaling pathway [PATH:ptr04012]
Environmental Information Processing; Signal transduction; Jak-STAT signaling pathway [PATH:ptr04630]
Environmental Information Processing; Signal transduction; FoxO signaling pathway [PATH:ptr04068]
Environmental Information Processing; Signal transduction; PI3K-Akt signaling pathway [PATH:ptr04151]
Cellular Processes; Cell motility; Regulation of actin cytoskeleton [PATH:ptr04810]
Cellular Processes; Cell communication; Focal adhesion [PATH:ptr04510]
Cellular Processes; Cell communication; Gap junction [PATH:ptr04540]
Organismal Systems; Immune system; Natural killer cell mediated cytotoxicity [PATH:ptr04650]
Organismal Systems; Immune system; T cell receptor signaling pathway [PATH:ptr04660]
Organismal Systems; Immune system; B cell receptor signaling pathway [PATH:ptr04662]
Organismal Systems; Immune system; Fc epsilon RI signaling pathway [PATH:ptr04664]
Organismal Systems; Immune system; Chemokine signaling pathway [PATH:ptr04062]
Organismal Systems; Endocrine system; Insulin signaling pathway [PATH:ptr04910]
Organismal Systems; Endocrine system; GnRH signaling pathway [PATH:ptr04912]
Organismal Systems; Endocrine system; Estrogen signaling pathway [PATH:ptr04915]
Organismal Systems; Endocrine system; Prolactin signaling pathway [PATH:ptr04917]
Organismal Systems; Nervous system; Neurotrophin signaling pathway [PATH:ptr04722]
Organismal Systems; Development; Dorso-ventral axis formation [PATH:ptr04320]
Human Diseases; Cancers; Pathways in cancer [PATH:ptr05200]
Human Diseases; Cancers; MicroRNAs in cancer [PATH:ptr05206]
Human Diseases; Cancers; Proteoglycans in cancer [PATH:ptr05205]
Human Diseases; Cancers; Glioma [PATH:ptr05214]
Human Diseases; Cancers; Acute myeloid leukemia [PATH:ptr05221]
Human Diseases; Cancers; Chronic myeloid leukemia [PATH:ptr05220]
Human Diseases; Cancers; Renal cell carcinoma [PATH:ptr05211]
Human Diseases; Cancers; Prostate cancer [PATH:ptr05215]
Human Diseases; Cancers; Endometrial cancer [PATH:ptr05213]
Human Diseases; Cancers; Non-small cell lung cancer [PATH:ptr05223]
Human Diseases; Substance dependence; Alcoholism [PATH:ptr05034]
Human Diseases; Infectious diseases; Hepatitis C [PATH:ptr05160]
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif Motif
Other DBs
NCBI-GI: 
NCBI-GeneID: 
UniProt: 
Position
14
AA seq 1301 aa AA seqDB search
MQQAPQPYEFFSEENSPKWRGLLVSALRKVQEQVHPTLSANEESLYYIEELIFQLLNKLC
MAQPRTVQDVEERVQKTFPHPIDKWAIADAQSAIEKRKRRNPLLLPVDKIHPSLKEVLGY
KVDYHVSLYIVAVLEYISADILKLAGNYVFNIRHYEISQQDIKVSMCADKVLMDMFDQDD
IGLVSLCEDEPSSSGELNYYDLVRTEIAEERQYLRELNMIIKVFREAFLSDRKLFKPSDI
EKIFSNISDIHELTVKLLGLIEDTVEMTDESSPHPLAGSCFEDLAEEQAFDPYETLSQDI
LSPEFHEHFNKLMARPAVALHFQSIADGFKEAVRYVLPRLMLVPVYHCWHYFELLKQLKA
CSEEQEDRECLNQAITALMNLQGSMDRIYKQYSPRRRPGEREYVARRCNEFIMHVPLTRI
GAMHERHIFLFDGLMISCKPNHGQTRLPGYSSAEYRLKEKFVMRKIQICDKEDTCEYKHA
FELVSKDENSIIFAAKSAEEKNNWMAALISLHYRSTLDRMLDSVLLKEENEQPLRLPSPE
VYRFVVKDSEENIVFEDNLQSRSGIPIIKGGTVVKLIERLTYHMYADPNFVRTFLTTYRS
FCKPQELLSLLIERFEIPEPEPTDADKLAIEKGEQPISADLKRFRKEYVQPVQLRILNVF
RHWVEHHFYDFERDLELLERLESFISSVRGKAMKKWVESIAKIIRRKKQAQANGISHNIT
FESPPPPIEWHISKPGQFETFDLMTLHPIEIARQLTLLESDLYRKVQPSELVGSVWTKED
KEINSPNLLKMIRHTTNLTLWFEKCIVEAENFEERVAVLSRIIEILQVFQDLNNFNGVLE
IVSAVNSVSVYRLDHTFEALQERKRKILDEAVELSQDHFKKYLVKLKSINPPCVPFFGIY
LTNILKTEEGNNDFLKKKGKDLINFSKRRKVAEITGEIQQYQNQPYCLRIEPDMRRFFEN
LNPMGSASEKEFTDYLFNKSLEIEPRNCKQPPRFPRKSTFSLKSPGIRPNTGRHGSTSGT
LRGHPTPLEREPCKISFSRIAETELESTVSAPTSPNTPSTPPVSASSDLSVFLDVDLNSS
CGSNSIFAPVLLPHSKSFFSSCGSLHKLSEEPLIPPPLPPRKKFDHDASNSKGNMKSDDD
PPAIPPRQPPPPKVKPRVPVPTGAFDGPLHSPPPPPPRDPLPDTPPPVPLRPPEHFINCP
FNLQPPPLGHLHRDSDWLRDISTCPNSPSTPPSTPSPRVPRRCYVLSSSQNNLAHPPAPP
VPPRQNSSPHLPKLPPKTYKRELSHPPLYRLPLLENAETPQ
NT seq 3906 nt NT seq  +upstreamnt  +downstreamnt
atgcagcaggcgccgcagccttacgagttcttcagcgaggagaacagtccgaaatggcgg
ggactgttggtctcggccctgcggaaggttcaggaacaagtgcatcccactctctcagct
aatgaagagtctctctattatattgaagagctgatttttcagctgcttaataaattatgc
atggcccagccaaggactgttcaagatgtagaggagcgagttcagaagacctttcctcac
ccaattgataaatgggccattgctgatgcacaatctgctatagaaaaacgaaaacgaaga
aatcctcttttactgcctgtggacaaaatccatccttcgttgaaggaagtattagggtac
aaagtggactaccatgtgtccctatatattgtggctgtactagagtatatctcagctgat
attttaaaattggctggtaattatgtttttaatatccggcattatgaaatatctcagcag
gacattaaagtgtcaatgtgtgcggataaggttttgatggacatgtttgatcaggatgac
ataggtttggtttctctctgtgaagatgaacctagttcttctggtgaattaaactactat
gatcttgtcagaactgaaatcgcagaagaaagacagtatctacgggaattaaatatgatc
ataaaagtgtttcgagaagcctttctttctgatagaaagctgtttaaaccttctgatatc
gaaaagatttttagtaacatttcagatatacatgaattgactgtgaaacttttaggtttg
attgaagacacagttgaaatgactgatgaaagcagtcctcatcccttagctggcagctgt
tttgaagatttggcagaagagcaagcatttgatccttatgaaacattatcacaggacatt
ctttcaccagagtttcatgaacatttcaataaattaatggccagacctgcagttgctcta
cactttcagtccattgctgatggttttaaagaggcagttcgttatgtccttccacgtctt
atgctggtgccagtgtatcactgttggcactactttgagttactaaagcaattgaaagca
tgtagtgaagaacaagaagacagagaatgtttgaaccaagctattactgctctcatgaat
ctccaaggtagcatggaccgaatttacaagcagtattcacctagacgtcgacctggagaa
cgcgaatatgttgcacggcggtgcaatgaattcattatgcatgtacccttgacaagaatc
ggtgccatgcatgagcggcatatttttctgtttgatggcttaatgatcagttgtaaacct
aatcatggccagactcggcttccaggttacagtagtgcagaatacaggttaaaagaaaaa
tttgtcatgaggaaaatacaaatttgtgataaagaagatacttgtgagtacaagcatgca
tttgaattagtatccaaagatgagaacagcataatatttgctgctaagtctgctgaagaa
aaaaacaactggatggcagcccttatttctcttcattatcgtagtactctagatcgaatg
ttagattcagtattattgaaagaagaaaatgagcaaccactgagattaccaagtcctgaa
gtatatcgttttgtagtaaaagactctgaggaaaacattgtttttgaagacaacttgcaa
agtagaagtggcatccccattattaaaggaggaactgtagtgaaattaattgaaaggtta
acatatcatatgtatgcagatcccaattttgttcgtacttttcttaccacatatcgttca
ttttgtaaaccacaggaattgctgagcttactgattgaacggtttgaaattccagagcca
gaacctactgatgcagacaaattggcaatagagaaaggcgagcagccaatcagtgcagac
cttaaaagatttcgcaaggaatatgtccaaccagtacaacttaggatcttaaatgtattt
cggcattgggttgaacatcatttttatgactttgaaagagacttggaattgcttgaaaga
ctagaatccttcatttcaagtgtaagagggaaagctatgaaaaaatgggtagagtcaatc
gctaagatcatcaggaggaagaagcaagctcaggcaaatggaataagccataatattacc
tttgaaagtccacctccaccaattgaatggcatatcagcaaaccaggacagtttgaaaca
tttgatctcatgacacttcatccaatagaaattgcacgtcagctgacacttttggagtct
gatctctacaggaaagttcaaccgtctgaacttgtagggagtgtgtggaccaaagaagat
aaagaaataaattctccaaatttattaaaaatgattcgccataccacaaatctcaccctc
tggtttgaaaaatgcattgtggaagcagaaaattttgaagaacgggtggcagtactaagt
agaattatagaaattctgcaagtttttcaagatttgaataatttcaatggcgtattggag
atagtcagtgcagtaaattcagtatcagtatacagactagaccatacctttgaggcattg
caggaaagaaaaaggaaaattttggacgaagctgtggaattaagtcaagatcactttaaa
aaatacctagtaaaacttaagtcaatcaatccaccttgtgtgcctttttttggaatatat
ttaacaaatattctgaagaccgaagaagggaataatgattttttaaaaaagaaagggaaa
gatttaatcaatttcagtaagaggaggaaagtagctgaaattactggagaaattcagcag
tatcagaatcagccttactgtttacggatagaaccagatatgaggagattctttgaaaac
cttaacccaatgggaagtgcatctgaaaaagagtttacagattatttgttcaacaagtca
ctagaaattgaacctcgaaactgcaaacagccacctcgatttcctaggaaatcaactttt
tccttaaaatctcctggaataaggcctaacacaggccgacatggctctacctcaggtact
ttacgaggtcacccaacaccattagaaagagaaccatgtaaaataagctttagtcggatt
gctgaaactgagctggaatcaacagtgtcagcaccaacctctccaaatacaccatctact
ccaccagtatctgcttcttcagaccttagtgtatttttagatgtggatctcaacagctcc
tgtggcagcaatagcatcttcgctccagtgcttttgccacattcaaagtctttctttagt
tcatgtggtagtttacataaactaagtgaagagcccctgattcctcctcctcttcctcct
cgaaaaaagtttgatcatgatgcttcaaattccaagggaaatatgaaatctgatgatgat
cctcctgctattccaccgagacagcctcctcctccaaaggtaaaacccagagttcctgtt
cctactggtgcatttgatgggcctctgcatagtccacctccgccaccaccaagagatcct
cttcctgatacccctccaccagttccccttcggcctccagaacactttataaactgtcca
tttaatcttcagccacctccactggggcatcttcacagagattcagactggctcagagac
attagtacgtgtccaaattcgccaagcactcctcctagcacaccctctccaagggtaccg
cgtcgatgctatgtgctcagttctagtcagaataatcttgctcatcctccagctccccct
gttccaccaaggcagaattcaagccctcatctgccaaaactgccaccaaagacttacaaa
cgggagctttcgcaccccccattgtacagactgcctttgctagaaaatgcagaaactccc
caatga

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