KEGG   Pan troglodytes (chimpanzee): 455776Help
Entry
455776            CDS       T01005                                 

Gene name
PRKACA
Definition
protein kinase, cAMP-dependent, catalytic, alpha
Orthology
K04345  
protein kinase A [EC:2.7.11.11]
Organism
ptr  Pan troglodytes (chimpanzee)
Pathway
MAPK signaling pathway
Ras signaling pathway
Calcium signaling pathway
cAMP signaling pathway
Chemokine signaling pathway
Oocyte meiosis
Apoptosis
Adrenergic signaling in cardiomyocytes
Vascular smooth muscle contraction
Wnt signaling pathway
Hedgehog signaling pathway
Gap junction
Platelet activation
Circadian entrainment
Long-term potentiation
Retrograde endocannabinoid signaling
Glutamatergic synapse
Cholinergic synapse
Serotonergic synapse
GABAergic synapse
Dopaminergic synapse
Olfactory transduction
Taste transduction
Inflammatory mediator regulation of TRP channels
Insulin signaling pathway
Insulin secretion
GnRH signaling pathway
Ovarian steroidogenesis
Progesterone-mediated oocyte maturation
Estrogen signaling pathway
Melanogenesis
Thyroid hormone synthesis
Thyroid hormone signaling pathway
Oxytocin signaling pathway
Endocrine and other factor-regulated calcium reabsorption
Vasopressin-regulated water reabsorption
Salivary secretion
Gastric acid secretion
Bile secretion
Parkinson's disease
Prion diseases
Cocaine addiction
Amphetamine addiction
Morphine addiction
Amoebiasis
HTLV-I infection
Epstein-Barr virus infection
Pathways in cancer
Viral carcinogenesis
Proteoglycans in cancer
Dilated cardiomyopathy
Brite
KEGG Orthology (KO) [BR:ptr00001]
 Environmental Information Processing
  Signal transduction
   04014 Ras signaling pathway
    455776 (PRKACA)
   04010 MAPK signaling pathway
    455776 (PRKACA)
   04310 Wnt signaling pathway
    455776 (PRKACA)
   04340 Hedgehog signaling pathway
    455776 (PRKACA)
   04020 Calcium signaling pathway
    455776 (PRKACA)
   04024 cAMP signaling pathway
    455776 (PRKACA)
 Cellular Processes
  Cell growth and death
   04114 Oocyte meiosis
    455776 (PRKACA)
   04210 Apoptosis
    455776 (PRKACA)
  Cellular commiunity
   04540 Gap junction
    455776 (PRKACA)
 Organismal Systems
  Immune system
   04611 Platelet activation
    455776 (PRKACA)
   04062 Chemokine signaling pathway
    455776 (PRKACA)
  Endocrine system
   04911 Insulin secretion
    455776 (PRKACA)
   04910 Insulin signaling pathway
    455776 (PRKACA)
   04912 GnRH signaling pathway
    455776 (PRKACA)
   04913 Ovarian Steroidogenesis
    455776 (PRKACA)
   04915 Estrogen signaling pathway
    455776 (PRKACA)
   04914 Progesterone-mediated oocyte maturation
    455776 (PRKACA)
   04921 Oxytocin signaling pathway
    455776 (PRKACA)
   04918 Thyroid hormone synthesis
    455776 (PRKACA)
   04919 Thyroid hormone signaling pathway
    455776 (PRKACA)
   04916 Melanogenesis
    455776 (PRKACA)
  Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    455776 (PRKACA)
   04270 Vascular smooth muscle contraction
    455776 (PRKACA)
  Digestive system
   04970 Salivary secretion
    455776 (PRKACA)
   04971 Gastric acid secretion
    455776 (PRKACA)
   04976 Bile secretion
    455776 (PRKACA)
  Excretory system
   04962 Vasopressin-regulated water reabsorption
    455776 (PRKACA)
   04961 Endocrine and other factor-regulated calcium reabsorption
    455776 (PRKACA)
  Nervous system
   04724 Glutamatergic synapse
    455776 (PRKACA)
   04727 GABAergic synapse
    455776 (PRKACA)
   04725 Cholinergic synapse
    455776 (PRKACA)
   04728 Dopaminergic synapse
    455776 (PRKACA)
   04726 Serotonergic synapse
    455776 (PRKACA)
   04720 Long-term potentiation
    455776 (PRKACA)
   04723 Retrograde endocannabinoid signaling
    455776 (PRKACA)
  Sensory system
   04740 Olfactory transduction
    455776 (PRKACA)
   04742 Taste transduction
    455776 (PRKACA)
   04750 Inflammatory mediator regulation of TRP channels
    455776 (PRKACA)
  Environmental adaptation
   04713 Circadian entrainment
    455776 (PRKACA)
 Human Diseases
  Cancers
   05200 Pathways in cancer
    455776 (PRKACA)
   05205 Proteoglycans in cancer
    455776 (PRKACA)
   05203 Viral carcinogenesis
    455776 (PRKACA)
  Neurodegenerative diseases
   05012 Parkinson's disease
    455776 (PRKACA)
   05020 Prion diseases
    455776 (PRKACA)
  Substance dependence
   05030 Cocaine addiction
    455776 (PRKACA)
   05031 Amphetamine addiction
    455776 (PRKACA)
   05032 Morphine addiction
    455776 (PRKACA)
  Cardiovascular diseases
   05414 Dilated cardiomyopathy (DCM)
    455776 (PRKACA)
  Infectious diseases
   05166 HTLV-I infection
    455776 (PRKACA)
   05169 Epstein-Barr virus infection
    455776 (PRKACA)
   05146 Amoebiasis
    455776 (PRKACA)
Enzymes [BR:ptr01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.11  cAMP-dependent protein kinase
     455776 (PRKACA)
Protein kinases [BR:ptr01001]
 Serine/threonine protein kinases: AGC group
  PKA family
   455776 (PRKACA)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif Motif
Other DBs
NCBI-GI: 
NCBI-GeneID: 
Ensembl: 
UniProt: 
Position
19
AA seq 427 aa AA seqDB search
MFTLGYHGAEEWASGETSLEPALEQCPCNCHGEEQGQLGAKVTAEPPKGTCYPSPRGLHP
RPGLPREGARGTAKSQGYKYLGWRRPWPWNVVKEFLAKAKEDFLKKWESPAQNTAHLDQF
ERIKTLGTGSFGRVMLVKHKETGNHYAMKILDKQKVVKLKQIEHTLNEKRILQAVNFPFL
VKLEFSFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLI
YRDLKPENLLIDQQGYIQVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWA
LGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGN
LKNGVNDIKNHKWFATTDWIAIYQRKVEAPFIPKFKGPGDTSNFDDYEEEEIRVSINEKC
GKEFSEF
NT seq 1284 nt NT seq  +upstreamnt  +downstreamnt
atgttcaccttgggataccatggggccgaggagtgggcatcaggcgagacttcccttgaa
ccagctctggagcaatgcccttgcaattgccatggagaggaacagggccagctgggggcc
aaggtgacagctgagccccccaagggcacctgctacccgagcccccgaggcctccatccc
aggcccggcctccccagagaaggggccagaggaacagccaaatcccaaggctataaatac
ctcggctggcgtcggccctggccgtggaatgtcgtgaaagaattcttagccaaagccaaa
gaagattttcttaaaaaatgggaaagtcccgctcagaacacagcccacttggatcagttt
gaacgaatcaagaccctcggcacgggctccttcgggcgggtgatgctggtgaaacacaag
gagaccgggaaccactatgccatgaagatcctcgacaaacagaaggtggtgaaactgaaa
cagatcgaacacaccctgaatgaaaagcgcatcctgcaagctgtcaactttccgttcctc
gtcaaactcgagttctccttcaaggacaactcaaacttatacatggtcatggagtacgtg
cccggcggggagatgttctcacacctacggcggatcggaaggttcagcgagccccatgcc
cgtttctacgcggcccagatcgtcctgacctttgagtatctgcactcgctggatctcatc
tacagggacctgaagccggagaatctgctcattgaccagcagggctacattcaggtgaca
gacttcggtttcgccaagcgcgtgaagggccgcacttggaccttgtgcggcacccctgag
tacctggcccctgagattatcctgagcaaaggctacaacaaggccgtggactggtgggcc
ctgggggttcttatctatgaaatggccgctggctacccgcccttcttcgcagaccagccc
atccagatctatgagaagatcgtctctgggaaggtgcggttcccttcccacttcagctct
gacttgaaggacctgctgcggaacctcctgcaggtagatctcaccaagcgctttgggaac
ctcaagaatggggtcaacgatatcaagaaccacaagtggtttgccacaactgactggatt
gccatctaccagaggaaggtggaagctcccttcataccaaagtttaaaggccctggggat
acgagtaactttgacgactatgaggaagaagaaatccgggtctccatcaatgagaagtgt
ggcaaggagttttctgagttttag

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