KEGG   Pan troglodytes (chimpanzee): 456067Help
Entry
456067            CDS       T01005                                 

Gene name
ARHGEF1
Definition
(RefSeq) Rho guanine nucleotide exchange factor (GEF) 1
  KO
K12330  
Rho guanine nucleotide exchange factor 1
Organism
ptr  Pan troglodytes (chimpanzee)
Pathway
Vascular smooth muscle contraction
Platelet activation
Regulation of actin cytoskeleton
Pathways in cancer
Proteoglycans in cancer
Brite
KEGG Orthology (KO) [BR:ptr00001]
 Cellular Processes
  Cell motility
   04810 Regulation of actin cytoskeleton
    456067 (ARHGEF1)
 Organismal Systems
  Immune system
   04611 Platelet activation
    456067 (ARHGEF1)
  Circulatory system
   04270 Vascular smooth muscle contraction
    456067 (ARHGEF1)
 Human Diseases
  Cancers
   05200 Pathways in cancer
    456067 (ARHGEF1)
   05205 Proteoglycans in cancer
    456067 (ARHGEF1)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif Motif
Other DBs
NCBI-GI: 
NCBI-GeneID: 
Ensembl: 
Position
19
AA seq 930 aa AA seqDB search
MASLSTWSSPAEPREMEDFARGAASPGPSRPGLVPVSIIGAEDEDFENELETNSEEQNSQ
FQSLEQVKRRPAHLMALLQHVALQFEPGPLLCCLHADMLGSLGPKEAKKAFLDFYHSFLE
KTAVLRVPVPPNVAFELDRTRADLISEDVQRRFVQEVVQSQQAAVGRQLEDFRSKRLMGM
TPWEQELAQLEAWVGRDRASYEARERHVAERLLMHLEEMQHTISTDEEKSAAVVNAIGLY
MRHLGVRTKSGDKKSGRNFFRKKVMGNRRSDEPAKTKKGLSSILDAARWNRGEPQVPDFR
HLKAEVDAEKPGATDRKGGVGMPSRDRNIGAPGQDTPGVSLHPLSLDSPDREPGADAPLE
LGDSSPQGPMSLESLAPPESTDEGAETESPEPGDEGEPGRSGLELEPEEPPGWRELVPPD
TLHSLPKSQVKRQEVISELLVTEAAHVRMLRVLHDLFFQPMAECLFFPLEELQNIFPSLD
ELIEVHSLFLDSLVKRRQESGYLIEEIGDVLLARFDGAEGSWFQKISSRFCSRQSFALEQ
LKAKQRKDPRFCAFVQEAESRPRCRRLQLKDMIPTEMQRLTKYPLLLQSIGQNTEEPTER
EKVELAAECCREILHHVNQAVRDMEDLLRLKDYQRRLDLSHLRQSSDPMLSEFKNLDITK
KKLVHEGPLTWRVTKDKAVEVHVLLLDDLLLLLQRQDERLLLKSHSRTLTPTPDGKTMLR
PVLRLTSAMTREVATDHKAFYVLFTWDQEAQIYELVAQTVSERKNWCALITETAGSLKVP
APASRPKPRPSPSRXGGPWRELEVQGVGPEGGAGFPPQLQNRLCVSMHMCECIPAPWSPD
SAPPCPWPVLSLKQLLFPAEEDNGAGPPRDGDGVPGGGPLSPARTQEIQENLLSLEETMK
QLEELEEEFCRLRPLLSQLGGNSVPQPGCT
NT seq 2793 nt NT seq  +upstreamnt  +downstreamnt
atggcttctctttccacctggagcagccctgcagagcccagggagatggaagacttcgcc
cgaggggcggcctccccaggcccctcccggcctggcctggttcccgtcagcatcatcggg
gctgaggatgaggattttgagaacgagctggagacaaactcggaagagcaaaacagccag
ttccagagcctggagcaggtgaagcggcgcccagcccacctcatggccctcctgcagcac
gtggccctgcagtttgagccaggacccctgctttgctgtctgcatgccgacatgctgggc
tcactgggccccaaggaggccaagaaggccttcctggacttctaccacagcttcctggag
aagacagcggttctccgggtgccggtccctcccaacgtcgcctttgaacttgaccgcact
agggctgacctcatctccgaggatgtccagcggcggttcgtgcaggaggtggtgcaaagc
cagcaggcagccgtgggccggcagctggaggacttccgctccaagcggctcatgggcatg
acgccctgggagcaggagctggcccagctggaggcttgggttgggcgggaccgagccagc
tacgaggcccgggagcggcacgtggcggagcggctgctcatgcacctggaggagatgcaa
cataccatctctaccgacgaagaaaagagtgctgccgtggtcaacgccattggcctgtac
atgcgccaccttggggtgcggaccaagagtggagacaagaagtcggggaggaacttcttc
cggaaaaaggtgatggggaaccggcggtcggacgagcctgccaagaccaagaaggggctg
agcagcatcctggatgccgcccgctggaaccggggagagccccaggttccagattttcga
cacctcaaagcagaggttgatgccgagaagccaggtgctacagaccggaagggaggcgtg
gggatgccctctcgggaccggaatatcggggctcctgggcaggacacccctggagtctct
ctgcaccctctgtccctggacagcccagaccgggaaccaggtgctgacgcccccctggag
ctgggggactcatccccacagggcccaatgagcctggagtccttggcgcccccagagagt
accgatgagggggccgaaaccgagagccccgagcctggagatgagggggagccggggcgg
tcgggactggagcttgaaccagaagagcctcccggctggcgggaactcgtccccccagac
accctgcacagcctgcccaagagccaggtgaagcggcaggaggtcatcagcgagctgctg
gtgacagaggcggcccacgtgcgcatgctgcgggtgctgcacgacctcttcttccagccc
atggcagaatgcctgttcttccccttggaggagctgcagaacatcttccccagcctggac
gagctcatcgaggtgcattccctgttcctcgattccctggtgaagcggaggcaggagagt
ggctacctcatcgaggagatcggagacgtgctgctggcccggtttgatggtgctgagggc
tcctggttccagaaaatctcctcccgcttctgcagccgccagtcatttgccttagagcag
ctcaaagccaagcaacgcaaggaccctcggttctgtgccttcgtgcaggaagctgagagc
cgcccgcggtgccgccgcctgcagctgaaggacatgatccccacggagatgcagcggcta
accaagtaccccctgctcctgcagagcatcgggcagaacacagaagagcccacagaacgg
gagaaagtggagctggcagccgagtgctgccgggaaattctacaccacgtcaaccaagcc
gtgcgtgacatggaggacctgctgaggctcaaggactatcagcggcgcctggacttgtcc
caccttcggcagagcagcgaccctatgctgagcgaattcaagaacctggacatcaccaag
aaaaaattggtccacgagggcccactgacgtggcgggtgactaaggacaaggcagtggag
gtgcatgtgctgctgctggacgacctgctgctgctgctccagcgccaggacgagcggctg
ctgctcaagtcccatagccggacactgacgcccacacccgatggcaagaccatgctgcgg
cccgtgctgcggctcacctccgccatgacccgcgaggtggccaccgatcacaaagccttc
tacgtcctttttacctgggaccaggaggcccagatatacgagctggtggcacagactgtg
tcggagcggaaaaactggtgtgccctcatcactgagactgccggatccctgaaagtccct
gcccctgcctctcgccctaagccccggcccagcccgagcaggtgaggggggccatggaga
gagctggaggttcagggagtggggccggaaggcggggcaggcttccctccacaactccag
aaccgtctctgtgtgagcatgcacatgtgtgaatgcatcccagccccctggtctcctgac
tccgcccccccttgcccctggccagtgctgtccctgaagcagcttctgtttccggcggag
gaagacaatggggcggggcctcctcgagatggggatggggtcccagggggcggccccctg
agcccagcacggacccaggaaatccaggagaacctgctcagcttggaggagaccatgaag
cagctggaggagttggaggaggaattttgccgcctgcgacccctcctgtctcagcttggg
gggaactctgtcccccagcctggctgcacttga

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