KEGG   Pan troglodytes (chimpanzee): 456067Help
Entry
456067            CDS       T01005                                 

Gene name
ARHGEF1
Definition
Rho guanine nucleotide exchange factor (GEF) 1
Orthology
K12330  
Rho guanine nucleotide exchange factor 1
Organism
ptr  Pan troglodytes (chimpanzee)
Pathway
Vascular smooth muscle contraction
Platelet activation
Regulation of actin cytoskeleton
Proteoglycans in cancer
Brite
KEGG Orthology (KO) [BR:ptr00001]
 Cellular Processes
  Cell motility
   04810 Regulation of actin cytoskeleton
    456067 (ARHGEF1)
 Organismal Systems
  Immune system
   04611 Platelet activation
    456067 (ARHGEF1)
  Circulatory system
   04270 Vascular smooth muscle contraction
    456067 (ARHGEF1)
 Human Diseases
  Cancers
   05205 Proteoglycans in cancer
    456067 (ARHGEF1)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif Motif
Other DBs
NCBI-GI: 
NCBI-GeneID: 
Ensembl: 
Position
19
AA seq 929 aa AA seqDB search
MDAVLPLLDPPGLATLLASIISNPQASVEQPSFPPDTGSVALVRLIKDTEDNSEEQNSQF
QSLEQVKRRPAHLMALLQHVALQFEPGPLLCCLHADMLGSLGPKEAKKAFLDFYHSFLEK
TAVLRVPVPPNVAFELDRTRADLISEDVQRRFVQEVVQSQQAAVGRQLEDFRSKRLMGMT
PWEQELAQLEAWVGRDRASYEARERHVAERLLMHLEEMQHTISTDEEKSAAVVNAIGLYM
RHLGVRTKSGDKKSGRNFFRKKVMGNRRSDEPAKTKKGLSSILDAARWNRGEPQVPDFRH
LKAEVDAEKPGATDRKGGVGMPSRDRNIGAPGQDTPGVSLHPLSLDSPDREPGADAPLEL
GDSSPQGPMSLESLAPPESTDEGAETESPEPGDEGEPGRSGLELEPEEPPGWRELVPPDT
LHSLPKSQVKRQEVISELLVTEAAHVRMLRVLHDLFFQPMAECLFFPLEELQNIFPSLDE
LIEVHSLFLDSLVKRRQESGYLIEEIGDVLLARFDGAEGSWFQKISSRFCSRQSFALEQL
KAKQRKDPRFCAFVQEAESRPRCRRLQLKDMIPTEMQRLTKYPLLLQSIGQNTEEPTERE
KVELAAECCREILHHVNQAVRDMEDLLRLKDYQRRLDLSHLRQSSDPMLSEFKNLDITKK
KLVHEGPLTWRVTKDKAVEVHVLLLDDLLLLLQRQDERLLLKSHSRTLTPTPDGKTMLRP
VLRLTSAMTREVATDHKAFYVLFTWDQEAQIYELVAQTVSERKNWCALITETAGSLKVPA
PASRPKPRPSPSRXGGPWRELEVQGVGPEGGAGFPPQLQNRLCVSMHMCECIPAPWSPDS
APPCPWPVLSLKQLLFPAEEDNGAGPPRDGDGVPGGGPLSPARTQEIQENLLSLEETMKQ
LEELEEEFCRLRPLLSQLGGNSVPQPGCT
NT seq 2790 nt NT seq  +upstreamnt  +downstreamnt
atggacgcagtgctccctctgctggaccccccaggccttgcgacactcctcgcctccatc
atctccaacccccaagcctctgtggagcagccctccttcccgcctgacacgggctccgtg
gcattagtcagactaattaaggacacagaagataactcggaagagcaaaacagccagttc
cagagcctggagcaggtgaagcggcgcccagcccacctcatggccctcctgcagcacgtg
gccctgcagtttgagccaggacccctgctttgctgtctgcatgccgacatgctgggctca
ctgggccccaaggaggccaagaaggccttcctggacttctaccacagcttcctggagaag
acagcggttctccgggtgccggtccctcccaacgtcgcctttgaacttgaccgcactagg
gctgacctcatctccgaggatgtccagcggcggttcgtgcaggaggtggtgcaaagccag
caggcagccgtgggccggcagctggaggacttccgctccaagcggctcatgggcatgacg
ccctgggagcaggagctggcccagctggaggcttgggttgggcgggaccgagccagctac
gaggcccgggagcggcacgtggcggagcggctgctcatgcacctggaggagatgcaacat
accatctctaccgacgaagaaaagagtgctgccgtggtcaacgccattggcctgtacatg
cgccaccttggggtgcggaccaagagtggagacaagaagtcggggaggaacttcttccgg
aaaaaggtgatggggaaccggcggtcggacgagcctgccaagaccaagaaggggctgagc
agcatcctggatgccgcccgctggaaccggggagagccccaggttccagattttcgacac
ctcaaagcagaggttgatgccgagaagccaggtgctacagaccggaagggaggcgtgggg
atgccctctcgggaccggaatatcggggctcctgggcaggacacccctggagtctctctg
caccctctgtccctggacagcccagaccgggaaccaggtgctgacgcccccctggagctg
ggggactcatccccacagggcccaatgagcctggagtccttggcgcccccagagagtacc
gatgagggggccgaaaccgagagccccgagcctggagatgagggggagccggggcggtcg
ggactggagcttgaaccagaagagcctcccggctggcgggaactcgtccccccagacacc
ctgcacagcctgcccaagagccaggtgaagcggcaggaggtcatcagcgagctgctggtg
acagaggcggcccacgtgcgcatgctgcgggtgctgcacgacctcttcttccagcccatg
gcagaatgcctgttcttccccttggaggagctgcagaacatcttccccagcctggacgag
ctcatcgaggtgcattccctgttcctcgattccctggtgaagcggaggcaggagagtggc
tacctcatcgaggagatcggagacgtgctgctggcccggtttgatggtgctgagggctcc
tggttccagaaaatctcctcccgcttctgcagccgccagtcatttgccttagagcagctc
aaagccaagcaacgcaaggaccctcggttctgtgccttcgtgcaggaagctgagagccgc
ccgcggtgccgccgcctgcagctgaaggacatgatccccacggagatgcagcggctaacc
aagtaccccctgctcctgcagagcatcgggcagaacacagaagagcccacagaacgggag
aaagtggagctggcagccgagtgctgccgggaaattctacaccacgtcaaccaagccgtg
cgtgacatggaggacctgctgaggctcaaggactatcagcggcgcctggacttgtcccac
cttcggcagagcagcgaccctatgctgagcgaattcaagaacctggacatcaccaagaaa
aaattggtccacgagggcccactgacgtggcgggtgactaaggacaaggcagtggaggtg
catgtgctgctgctggacgacctgctgctgctgctccagcgccaggacgagcggctgctg
ctcaagtcccatagccggacactgacgcccacacccgatggcaagaccatgctgcggccc
gtgctgcggctcacctccgccatgacccgcgaggtggccaccgatcacaaagccttctac
gtcctttttacctgggaccaggaggcccagatatacgagctggtggcacagactgtgtcg
gagcggaaaaactggtgtgccctcatcactgagactgccggatccctgaaagtccctgcc
cctgcctctcgccctaagccccggcccagcccgagcaggtgaggggggccatggagagag
ctggaggttcagggagtggggccggaaggcggggcaggcttccctccacaactccagaac
cgtctctgtgtgagcatgcacatgtgtgaatgcatcccagccccctggtctcctgactcc
gcccccccttgcccctggccagtgctgtccctgaagcagcttctgtttccggcggaggaa
gacaatggggcggggcctcctcgagatggggatggggtcccagggggcggccccctgagc
ccagcacggacccaggaaatccaggagaacctgctcagcttggaggagaccatgaagcag
ctggaggagttggaggaggaattttgccgcctgcgacccctcctgtctcagcttgggggg
aactctgtcccccagcctggctgcacttga

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