KEGG   Pan troglodytes (chimpanzee): 456390Help
Entry
456390            CDS       T01005                                 

Gene name
MAP2K2
Definition
mitogen-activated protein kinase kinase 2
Orthology
K04369  
mitogen-activated protein kinase kinase 2 [EC:2.7.12.2]
Organism
ptr  Pan troglodytes (chimpanzee)
Pathway
MAPK signaling pathway
ErbB signaling pathway
Ras signaling pathway
Rap1 signaling pathway
HIF-1 signaling pathway
FoxO signaling pathway
PI3K-Akt signaling pathway
Vascular smooth muscle contraction
VEGF signaling pathway
Gap junction
Toll-like receptor signaling pathway
Natural killer cell mediated cytotoxicity
T cell receptor signaling pathway
B cell receptor signaling pathway
Fc epsilon RI signaling pathway
Long-term potentiation
Neurotrophin signaling pathway
Long-term depression
Regulation of actin cytoskeleton
Insulin signaling pathway
GnRH signaling pathway
Estrogen signaling pathway
Melanogenesis
Prolactin signaling pathway
Thyroid hormone signaling pathway
Oxytocin signaling pathway
Prion diseases
Hepatitis B
Influenza A
Pathways in cancer
Proteoglycans in cancer
MicroRNAs in cancer
Renal cell carcinoma
Endometrial cancer
Glioma
Prostate cancer
Thyroid cancer
Melanoma
Bladder cancer
Chronic myeloid leukemia
Acute myeloid leukemia
Non-small cell lung cancer
Class
Environmental Information Processing; Signal transduction; Ras signaling pathway [PATH:ptr04014]
Environmental Information Processing; Signal transduction; Rap1 signaling pathway [PATH:ptr04015]
Environmental Information Processing; Signal transduction; MAPK signaling pathway [PATH:ptr04010]
Environmental Information Processing; Signal transduction; ErbB signaling pathway [PATH:ptr04012]
Environmental Information Processing; Signal transduction; VEGF signaling pathway [PATH:ptr04370]
Environmental Information Processing; Signal transduction; HIF-1 signaling pathway [PATH:ptr04066]
Environmental Information Processing; Signal transduction; FoxO signaling pathway [PATH:ptr04068]
Environmental Information Processing; Signal transduction; PI3K-Akt signaling pathway [PATH:ptr04151]
Cellular Processes; Cell motility; Regulation of actin cytoskeleton [PATH:ptr04810]
Cellular Processes; Cell communication; Gap junction [PATH:ptr04540]
Organismal Systems; Immune system; Toll-like receptor signaling pathway [PATH:ptr04620]
Organismal Systems; Immune system; Natural killer cell mediated cytotoxicity [PATH:ptr04650]
Organismal Systems; Immune system; T cell receptor signaling pathway [PATH:ptr04660]
Organismal Systems; Immune system; B cell receptor signaling pathway [PATH:ptr04662]
Organismal Systems; Immune system; Fc epsilon RI signaling pathway [PATH:ptr04664]
Organismal Systems; Endocrine system; Insulin signaling pathway [PATH:ptr04910]
Organismal Systems; Endocrine system; GnRH signaling pathway [PATH:ptr04912]
Organismal Systems; Endocrine system; Estrogen signaling pathway [PATH:ptr04915]
Organismal Systems; Endocrine system; Prolactin signaling pathway [PATH:ptr04917]
Organismal Systems; Endocrine system; Oxytocin signaling pathway [PATH:ptr04921]
Organismal Systems; Endocrine system; Thyroid hormone signaling pathway [PATH:ptr04919]
Organismal Systems; Endocrine system; Melanogenesis [PATH:ptr04916]
Organismal Systems; Circulatory system; Vascular smooth muscle contraction [PATH:ptr04270]
Organismal Systems; Nervous system; Long-term potentiation [PATH:ptr04720]
Organismal Systems; Nervous system; Long-term depression [PATH:ptr04730]
Organismal Systems; Nervous system; Neurotrophin signaling pathway [PATH:ptr04722]
Human Diseases; Cancers; Pathways in cancer [PATH:ptr05200]
Human Diseases; Cancers; MicroRNAs in cancer [PATH:ptr05206]
Human Diseases; Cancers; Proteoglycans in cancer [PATH:ptr05205]
Human Diseases; Cancers; Glioma [PATH:ptr05214]
Human Diseases; Cancers; Thyroid cancer [PATH:ptr05216]
Human Diseases; Cancers; Acute myeloid leukemia [PATH:ptr05221]
Human Diseases; Cancers; Chronic myeloid leukemia [PATH:ptr05220]
Human Diseases; Cancers; Melanoma [PATH:ptr05218]
Human Diseases; Cancers; Renal cell carcinoma [PATH:ptr05211]
Human Diseases; Cancers; Bladder cancer [PATH:ptr05219]
Human Diseases; Cancers; Prostate cancer [PATH:ptr05215]
Human Diseases; Cancers; Endometrial cancer [PATH:ptr05213]
Human Diseases; Cancers; Non-small cell lung cancer [PATH:ptr05223]
Human Diseases; Neurodegenerative diseases; Prion diseases [PATH:ptr05020]
Human Diseases; Infectious diseases; Influenza A [PATH:ptr05164]
Human Diseases; Infectious diseases; Hepatitis B [PATH:ptr05161]
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif Motif
Other DBs
NCBI-GI: 
NCBI-GeneID: 
Ensembl: 
Position
19
AA seq 303 aa AA seqDB search
MARKLIHLEIKPAIRNQIIRELQVLHECNSPYIVGFYGAFYSDGEISICMEHMDGGSLDQ
VLKEAKRIPEEILGKVSIAVLRGLAYLREKHQIMHRDVKPSNILVNSRGEIKLCDFGVSG
QLIDSMANSFVGTRSYMAPERLQGTHYSVQSDIWSMGLSLVELAVGRYPIPPPDAKELEA
IFGRPVVDGEEGEPHSISPRPRPPGRPVSGHGMDSRPAMAIFELLDYIVNEPPPKLPNGV
FTPDFQEFVNKCLIKNPAERADLKMLTNHTFIKRSEVEEVDFAGWLCKTLRLNQPGTPTR
TAV
NT seq 912 nt NT seq  +upstreamnt  +downstreamnt
atggccaggaagctgatccaccttgagatcaagccggccatccggaaccagatcatccgc
gagctgcaggtcctgcacgaatgcaactcgccgtacatcgtgggcttctacggggccttc
tacagtgacggggagatcagcatctgtatggaacacatggatggcggctccctggaccag
gtgctgaaagaggccaagaggattcccgaggagatcctggggaaagtcagcatcgcggtt
ctccggggcttggcgtacctccgagagaagcaccagatcatgcaccgagatgtgaagccc
tccaacatcctcgtgaactctagaggggagatcaagctgtgtgacttcggggtgagcggc
cagctcatcgactccatggccaactccttcgtgggcacgcgctcctacatggctccggag
cggttgcagggcacacattactcggtgcagtcggacatctggagcatgggcctgtccctg
gtggagctggccgtcggaaggtaccccatccccccgcccgacgccaaagagctggaggcc
atctttggccggcccgtggtcgacggggaagaaggagagcctcacagcatctcgcctcgg
ccgaggccccccgggcgccccgtcagcggtcacgggatggatagccggcccgccatggcc
atctttgaactcctggactatattgtgaacgagccgcctcctaagctgcccaacggtgtg
ttcacccccgacttccaggagtttgtcaataaatgcctcatcaagaacccagcggagcgg
gcggacctgaagatgctcacaaaccacaccttcatcaagcggtccgaggtggaagaagtg
gattttgctggctggttgtgtaaaaccctgcggctgaaccagcccggcacacccacgcgc
accgccgtgtga

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