KEGG   Pan troglodytes (chimpanzee): 458602Help
Entry
458602            CDS       T01005                                 

Gene name
PFKL
Definition
phosphofructokinase, liver
Orthology
K00850  
6-phosphofructokinase 1 [EC:2.7.1.11]
Organism
ptr  Pan troglodytes (chimpanzee)
Pathway
Glycolysis / Gluconeogenesis
Pentose phosphate pathway
Fructose and mannose metabolism
Galactose metabolism
Metabolic pathways
Carbon metabolism
Biosynthesis of amino acids
RNA degradation
AMPK signaling pathway
Central carbon metabolism in cancer
Module
Glycolysis (Embden-Meyerhof pathway), glucose => pyruvate
Brite
KEGG Orthology (KO) [BR:ptr00001]
 Metabolism
  Overview
   01200 Carbon metabolism
    458602 (PFKL)
   01230 Biosynthesis of amino acids
    458602 (PFKL)
  Carbohydrate metabolism
   00010 Glycolysis / Gluconeogenesis
    458602 (PFKL)
   00030 Pentose phosphate pathway
    458602 (PFKL)
   00051 Fructose and mannose metabolism
    458602 (PFKL)
   00052 Galactose metabolism
    458602 (PFKL)
 Genetic Information Processing
  Folding, sorting and degradation
   03018 RNA degradation
    458602 (PFKL)
 Environmental Information Processing
  Signal transduction
   04152 AMPK signaling pathway
    458602 (PFKL)
 Human Diseases
  Cancers
   05230 Central carbon metabolism in cancer
    458602 (PFKL)
Enzymes [BR:ptr01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.1  Phosphotransferases with an alcohol group as acceptor
    2.7.1.11  6-phosphofructokinase
     458602 (PFKL)
Protein phosphatases and associated proteins [BR:ptr01009]
 Protein Ser/ Thr phosphatases
  Phosphoprotein phosphatases (PPPs)
   Protein phosphatase-1
    PP1-interacting proteins (PIPs)
     458602 (PFKL)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif
Pfam: 
Motif
Other DBs
NCBI-GI: 
NCBI-GeneID: 
UniProt: 
Position
21
AA seq 780 aa AA seqDB search
MAAVDLEKLRASGAGKAIGVLTSGGDAQGMNAAVRAVTRMGIYVGAKVFLIYEGYEGLVE
GGENIKQANWLSVSNIIQLGGTIIGSARCKAFTTREGRRAAAYNLVQHGITNLCVIGGDG
SLTGANIFRSEWGSLLEELVAEGKISETTARTYSHLNIAGLVGSIDNDFCGTDMTIGTDS
ALHRIMEVIDAITTTAQSHQRTFVLEVMGRHCGYLALVSALASGADWLFIPEAPPEDGWE
NFMCERLGETRSRGSRLNIIIIAEGAIDRNGKPISSSYVKDLVVQRLGFDTRVTVLGHVQ
RGGTPSAFDRILSSKMGMEAVMALLEATPDTPACVVTLSGNQSVRLPLMECVQMTKEVQK
AMDDKRFDEATQLRGGSFENNWNIYKLLAHQKPPKEKSNFSLAILNVGAPAAGMNAAVRS
AVRTGISHGHTVYVVHDGFEGLAKGQVQEVGWHDVAGWLGRGGSMLGTKRTLPKGQLESI
VENIRIYGIHALLVVGGFEAYEGVLQLVEARGRYEELCIVMCVIPATISNNVPGTDFSLG
SDTAVNAAMESCDRIKQSASGTKRRVFIVETMGGYCGYLATVTGIAVGADAAYVFEDPFN
IHDLKVNVEHMTEKMKTDIQRGLVLRNEKCHDYYTTEFLYNLYSSEGKGVFDCRTNVLGH
LQQGGAPTPFDRNYGTKLGVKAMLWLSEKLREVYRKGRVFANAPDSACVIGLKKKAVAFS
PVTELKKDTDFEHRMPREQWWLSLRLMLKMLAQYRISMAAYVSGELEHVTRRTLSMDKGF
NT seq 2343 nt NT seq  +upstreamnt  +downstreamnt
atggccgcggtggacctggagaagctgcgggcgtcgggcgcgggcaaggccatcggcgtc
ctgaccagcggcggcgacgcgcaaggcatgaacgctgctgtccgggctgtgacgcgcatg
ggcatttatgtgggtgccaaagtcttcctcatctacgagggctatgagggcctcgtggag
ggaggtgagaacatcaagcaggccaactggctgagcgtctccaacatcatccagctgggc
ggcactatcattggcagcgctcgctgcaaggcctttaccaccagggaggggcgccgggca
gcggcctacaacctggtccagcacggcatcaccaacctgtgcgtcatcggcggggatggc
agcctcacgggtgccaacatcttccgcagcgagtggggcagcctgctggaggagctggtg
gcggaaggtaagatctcagagactacggcccggacctactcgcacctgaacatcgcgggc
ctagtgggctccattgataacgacttctgcggcaccgacatgaccattggcacggactcg
gccctccaccgcatcatggaggtcatcgatgccatcaccaccactgcccagagccaccag
aggaccttcgtgctggaagtgatgggccggcactgcgggtacctggcgctggtatctgca
ctggcctcaggggccgactggctgttcatccccgaggctccacccgaggacggctgggag
aacttcatgtgcgagaggctgggtgagactcggagccgtgggtcccgactgaacatcatc
attatcgctgagggtgccattgaccgcaacgggaagcccatctcgtccagctacgtgaag
gacctggtggttcagaggctgggcttcgacacccgtgtaactgtgctgggccacgtgcag
cggggagggacgccctctgccttcgaccgaatcctgagcagcaagatgggcatggaggcg
gtgatggcgctgctggaagccacgcctgacacgccagcctgcgtggtcaccctctcgggg
aaccagtcagtgcggctgcccctcatggagtgtgtgcagatgaccaaggaagtgcaaaaa
gccatggatgacaagaggtttgacgaggccacccagctccgtggcgggagcttcgagaac
aactggaacatttacaagctcctcgcccaccagaagccccctaaggagaagtctaacttc
tccctggccatcctgaatgtgggggccccggcggctggcatgaatgcggccgtgcgctcg
gcggtgcggaccggcatctcccacggacacacagtatacgtggtgcatgatggcttcgaa
ggcctagccaagggtcaggtgcaagaagtgggctggcacgacgtggccggctggttgggg
cgtggtggctccatgctggggaccaagaggaccctgcccaagggccagctggagtccatc
gtggagaacatccgcatctatggtattcacgccctgctggtggttggcgggttcgaggcc
tatgaaggggtgctgcagctggtggaggctcgcgggcgctacgaggagctctgcatcgtc
atgtgtgtcatcccagccaccatcagcaacaacgtccctggcaccgacttcagcctgggc
tctgacactgctgtaaatgccgccatggagagctgtgaccgcatcaaacagtccgcctcg
gggaccaagcgccgtgtgttcatcgtggagaccatggggggttactgtggctacctggcc
accgtgactggcattgctgtgggggccgacgccgcctacgtctttgaggaccctttcaac
atccatgacttaaaggtcaacgtggagcacatgacggagaagatgaagacagacattcag
aggggcctggtgctgcggaacgagaagtgccatgactactacaccacagagttcctgtac
aacctgtactcatcagagggcaagggtgtgttcgactgcaggaccaacgtcctgggccac
ctgcagcagggtggcgctccaaccccctttgaccggaactacgggaccaagctgggggtg
aaggccatgctgtggttgtcggagaagctgcgcgaggtttaccgcaagggacgggtgttc
gccaatgccccagactcggcctgcgtgatcggcctgaagaagaaggcggtggccttcagc
cccgtcactgagctcaagaaagatactgatttcgagcaccgcatgccacgggagcagtgg
tggctgagcctgcggctcatgctgaagatgctggcacaataccgcatcagtatggccgcc
tacgtgtcaggggagctggagcacgtgacccgccgcaccctgagcatggacaagggcttc
tga

DBGET integrated database retrieval system