KEGG T01005: 459118

Pan troglodytes (chimpanzee): 459118

Entry

459118            CDS       T01005

Symbol

PPP1CB

Name

(RefSeq) serine/threonine-protein phosphatase PP1-beta catalytic subunit isoform X1

K06269

serine/threonine-protein phosphatase PP1 catalytic subunit [EC:3.1.3.16]

Organism

ptr Pan troglodytes (chimpanzee)

Pathway

ptr03015

mRNA surveillance pathway

ptr04022

cGMP-PKG signaling pathway

ptr04024

cAMP signaling pathway

ptr04114

Oocyte meiosis

ptr04218

Cellular senescence

ptr04261

Adrenergic signaling in cardiomyocytes

ptr04270

Vascular smooth muscle contraction

ptr04390

Hippo signaling pathway

ptr04510

Focal adhesion

ptr04611

Platelet activation

ptr04720

Long-term potentiation

ptr04728

Dopaminergic synapse

ptr04750

Inflammatory mediator regulation of TRP channels

ptr04810

Regulation of actin cytoskeleton

ptr04910

Insulin signaling pathway

ptr04921

Oxytocin signaling pathway

ptr04931

Insulin resistance

ptr05031

Amphetamine addiction

ptr05034

Alcoholism

ptr05168

Herpes simplex virus 1 infection

ptr05205

Proteoglycans in cancer

ptr05415

Diabetic cardiomyopathy

Brite

KEGG Orthology (KO) [BR:ptr00001]
09120 Genetic Information Processing
  09122 Translation
   03015 mRNA surveillance pathway
    459118 (PPP1CB)
09130 Environmental Information Processing
  09132 Signal transduction
   04390 Hippo signaling pathway
    459118 (PPP1CB)
   04024 cAMP signaling pathway
    459118 (PPP1CB)
   04022 cGMP-PKG signaling pathway
    459118 (PPP1CB)
09140 Cellular Processes
  09143 Cell growth and death
   04114 Oocyte meiosis
    459118 (PPP1CB)
   04218 Cellular senescence
    459118 (PPP1CB)
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    459118 (PPP1CB)
  09142 Cell motility
   04810 Regulation of actin cytoskeleton
    459118 (PPP1CB)
09150 Organismal Systems
  09151 Immune system
   04611 Platelet activation
    459118 (PPP1CB)
  09152 Endocrine system
   04910 Insulin signaling pathway
    459118 (PPP1CB)
   04921 Oxytocin signaling pathway
    459118 (PPP1CB)
  09153 Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    459118 (PPP1CB)
   04270 Vascular smooth muscle contraction
    459118 (PPP1CB)
  09156 Nervous system
   04728 Dopaminergic synapse
    459118 (PPP1CB)
   04720 Long-term potentiation
    459118 (PPP1CB)
  09157 Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    459118 (PPP1CB)
09160 Human Diseases
  09161 Cancer: overview
   05205 Proteoglycans in cancer
    459118 (PPP1CB)
  09172 Infectious disease: viral
   05168 Herpes simplex virus 1 infection
    459118 (PPP1CB)
  09165 Substance dependence
   05031 Amphetamine addiction
    459118 (PPP1CB)
   05034 Alcoholism
    459118 (PPP1CB)
  09166 Cardiovascular disease
   05415 Diabetic cardiomyopathy
    459118 (PPP1CB)
  09167 Endocrine and metabolic disease
   04931 Insulin resistance
    459118 (PPP1CB)
09180 Brite Hierarchies
  09181 Protein families: metabolism
   01009 Protein phosphatases and associated proteins [BR:ptr01009]
    459118 (PPP1CB)
  09182 Protein families: genetic information processing
   03021 Transcription machinery [BR:ptr03021]
    459118 (PPP1CB)
   03019 Messenger RNA biogenesis [BR:ptr03019]
    459118 (PPP1CB)
   03041 Spliceosome [BR:ptr03041]
    459118 (PPP1CB)
Enzymes [BR:ptr01000]
3. Hydrolases
  3.1  Acting on ester bonds
   3.1.3  Phosphoric-monoester hydrolases
    3.1.3.16  protein-serine/threonine phosphatase
     459118 (PPP1CB)
Protein phosphatases and associated proteins [BR:ptr01009]
Protein serine/threonine phosphatases
  Phosphoprotein phosphatases (PPPs)
   Protein phosphatase-1
    Catalytic subunits
     459118 (PPP1CB)
Transcription machinery [BR:ptr03021]
Eukaryotic type
  RNA polymerase II system
   Other transcription-related factors
    Transcription termination factor
     459118 (PPP1CB)
Messenger RNA biogenesis [BR:ptr03019]
Eukaryotic type
  mRNA processing factors
   3' end processing
    Cleavage and polyadenylation specificity factor (CPSF) complex
     459118 (PPP1CB)
Spliceosome [BR:ptr03041]
Other splicing related proteins
  Spliceosome associated proteins (SAPs)
   Other SAPs
    459118 (PPP1CB)

SSDB

Motif

Pfam:

Metallophos STPPase_N

Other DBs

NCBI-GeneID:

NCBI-ProteinID:

Ensembl:

VGNC:

UniProt:

Position

2A:28765883..28817459

AA seq 327 aa
MADGELNVDSLITRLLEVRGCRPGKIVQMTEAEVRGLCIKSREIFLSQPILLELEAPLKI
CGDIHGQYTDLLRLFEYGGFPPEANYLFLGDYVDRGKQSLETICLLLAYKIKYPENFFLL
RGNHECASINRIYGFYDECKRRFNIKLWKTFTDCFNCLPIAAIVDEKIFCCHGGLSPDLQ
SMEQIRRIMRPTDVPDTGLLCDLLWSDPDKDVQGWGENDRGVSFTFGADVVSKFLNRHDL
DLICRAHQVVEDGYEFFAKRQLVTLFSAPNYCGEFDNAGGMMSVDETLMCSFQILKPSEK
KAKYQYGGLNSGRPVTPPRTANPPKKR

NT seq 984 nt +upstreamnt +downstreamnt
atggcggacggggagctgaacgtggacagcctcatcacccggctgctggaggtacgagga
tgtcgtccaggaaagattgtgcagatgactgaagcagaagttcgaggcttatgtatcaag
tctcgggagatctttctcagccagcctattcttttggaattggaagcaccgctgaaaatt
tgtggagatattcatggacagtatacagatttactgagattatttgaatatggaggtttc
ccaccagaagccaactatcttttcttaggagattatgtggacagaggaaagcagtctttg
gaaaccatttgtttgctattggcttataaaatcaaatatccagagaacttctttctctta
agaggaaaccatgagtgtgctagcatcaatcgcatttatggattctatgatgaatgcaaa
cgaagatttaatattaaattgtggaagaccttcactgattgttttaactgtctgcctata
gcagccattgtggatgagaagatcttctgttgtcatggaggattgtcaccagacctgcaa
tctatggagcagattcggagaattatgagacctactgatgtccctgatacaggtttgctc
tgtgatttgctatggtctgatccagataaggatgtgcaaggctggggagaaaatgatcgt
ggtgtttcctttacttttggagctgatgtagtcagtaaatttctgaatcgtcatgattta
gatttgatttgtcgagctcatcaggtggtggaagatggatatgaattttttgctaaacga
cagttggtaaccttattttcagccccaaattactgtggcgagtttgataatgctggtgga
atgatgagtgtggatgaaactttgatgtgttcatttcagatattgaaaccatctgaaaag
aaagctaagtaccagtatggtggactgaattctggacgtcctgtcactccacctcgaaca
gctaatccgccgaagaaaaggtga

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