KEGG   Pan troglodytes (chimpanzee): 460457Help
Entry
460457            CDS       T01005                                 

Gene name
CACNA2D3
Definition
calcium channel, voltage-dependent, alpha 2/delta subunit 3
Orthology
K04860  
voltage-dependent calcium channel alpha-2/delta-3
Organism
ptr  Pan troglodytes (chimpanzee)
Pathway
MAPK signaling pathway
Cardiac muscle contraction
Adrenergic signaling in cardiomyocytes
Oxytocin signaling pathway
Hypertrophic cardiomyopathy (HCM)
Arrhythmogenic right ventricular cardiomyopathy (ARVC)
Dilated cardiomyopathy
Brite
KEGG Orthology (KO) [BR:ptr00001]
 Environmental Information Processing
  Signal transduction
   04010 MAPK signaling pathway
    460457 (CACNA2D3)
 Organismal Systems
  Endocrine system
   04921 Oxytocin signaling pathway
    460457 (CACNA2D3)
  Circulatory system
   04260 Cardiac muscle contraction
    460457 (CACNA2D3)
   04261 Adrenergic signaling in cardiomyocytes
    460457 (CACNA2D3)
 Human Diseases
  Cardiovascular diseases
   05410 Hypertrophic cardiomyopathy (HCM)
    460457 (CACNA2D3)
   05412 Arrhythmogenic right ventricular cardiomyopathy (ARVC)
    460457 (CACNA2D3)
   05414 Dilated cardiomyopathy (DCM)
    460457 (CACNA2D3)
Ion channels [BR:ptr04040]
 Voltage-gated cation channels
  Ca2+ channel, CACN alpha-2 delta
   460457 (CACNA2D3)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif Motif
Other DBs
NCBI-GI: 
NCBI-GeneID: 
Ensembl: 
UniProt: 
Position
3
AA seq 1069 aa AA seqDB search
MAGPGSPRRASRGASALLAAALLYAALGDVVRSEQQIPLSVVKLWASAFGGEIKSIAAKY
SGSQLLQKKYKEYEKDVAIEEIDGLQLVKKLAKNMEEMFHKKSEAVRRLVEAAEEAHLKH
EFDADLQYEYFNAVLINERDKDGNFLELGKEFILAPNDHFNNLPVNISLSDVQVPTNMYN
KDPAIVNGVYWSESLNKVFVDNFDRDPSLIWQYFGSAKGFFRQYPGIKWEPDENGVIAFD
CRNRKWYIQAATSPKDVVILVDVSGSMKGLRLTIAKQTVSSILDTLGDDDFFNIIAYNEE
LHYVEPCLNGTLVQADRTNKEHFREHLDKLFAKGIGMLDIALNEAFNILSDVSSSLICLS
HPLENRWVRIFTYLIGREAAFADNLKWMACANKGFFTQISTLADVQENVMEYLHVLSRPK
VIDQEHDVVWTEAYIDSTLPQAQKLTDDQGPVLMTTVAMPVFSKQNETRSKGILLGVVGT
DVPVKELLKTIPKYKLGIHGYAFAITNNGYILTHPELRLLYEEGKKRRKPNYSSVDLSEV
EWEDRDDVLRNAMVNRKTGKFSMEVKKTVDKGKRVLVMTNDYYYTDIKGTPFSLGVALSR
GHGKYFFRGNVTIEEGLHDLEHPDVSLADEWSYCNTDLHPEHRHLSQLEAIKLYLKGKEP
LLQCDKELIQEVLFDAVVSAPIEAYWTSLALNKSENSDKGVEVAFLGTRTGLSRINLFVG
AEQLTNQDFLKAGDKENIFNADHFPLWYRRAAEQIPGSFVYSIPFSTGPVNKSNVVTAST
SIQLLDERKSPVVAAVGIQMKLEFFQRKFWTASRQCASLDGKCSISCDDETVNCYLIDNN
GFILVSEDYTQTGDFFGEIEGAVMNKLLTMGSFKRITLYDYQAMCRANKESSDGAHGLLD
PYNAFLSAVKWIMTELVLFLVEFNLCSWWHSDMTAKAQKLKQTLEPCDTEYPAFVSERTI
KETTGNIACEDCSKSFVIQQIPSSNLFMVVVDSSCLCESVAPITMAPIEIRYNESLKCER
LKAQKIRRRPESCHGFHPEENARECGGAPSLEAQTVLLLLPLLLMLFSR
NT seq 3210 nt NT seq  +upstreamnt  +downstreamnt
atggccgggccgggctcgccgcgccgcgcgtcccggggggcctcggcgcttctcgccgcc
gcgcttctctacgccgcgctgggggacgtggtgcgctcggagcagcagataccgctctcc
gtggtgaagctctgggcctcggcttttggtggggagataaaatccattgctgctaagtac
tccggttcccagcttctgcaaaagaaatacaaagagtatgagaaagacgttgccatagaa
gaaatcgatggcctccaactggtaaagaagctggcaaagaacatggaagagatgtttcac
aagaagtctgaggccgtcaggcgtctggtggaggctgcagaagaagcacacctgaaacat
gaatttgatgcagacttacagtatgaatacttcaatgctgtgctgataaatgaaagggac
aaagacgggaattttttggagctggggaaggaattcatcttagccccaaatgaccatttt
aataatttgcctgtgaacatcagtctaagtgacgtccaagtaccaacgaacatgtacaac
aaagaccctgcaattgtcaatggggtttattggtctgaatctctaaacaaagtttttgta
gataactttgaccgtgacccatctctcatatggcagtactttggaagtgcaaagggcttt
tttaggcagtatccggggattaaatgggaaccagatgagaatggagtcattgccttcgac
tgcaggaaccgaaaatggtacatccaggcagcaacttctccgaaagacgtggtcatttta
gttgacgtcagtggcagcatgaaaggactccgtctgactatcgcgaagcaaacagtctca
tccattttggatacacttggggatgatgacttcttcaacataattgcttataatgaggag
cttcactatgtggaaccttgcctgaatggaactttggtgcaagccgacaggacaaacaaa
gagcacttcagggagcatctggacaaacttttcgccaaaggaattggaatgttggatata
gctctgaatgaggccttcaacattctgagtgatgtaagttcctctttgatttgcctttct
catcccttggagaatagatgggttcgcatcttcacatacctcattggacgagaggctgcg
tttgcagacaatctaaagtggatggcctgtgccaacaaaggattttttacccagatctcc
accttggctgatgtgcaggagaatgtcatggaataccttcacgtgcttagccggcccaaa
gtcatcgaccaggagcatgatgtggtgtggaccgaagcttacattgacagcactctccct
caggcacaaaagctgactgatgatcagggccccgtcctgatgaccactgtagccatgcct
gtgtttagtaagcagaacgaaaccagatcgaagggcattcttctgggagtggttggcaca
gatgtcccagtcaaagaacttctgaagaccatccccaaatacaagttagggattcacggt
tatgcctttgcaatcacaaataatggatatatcctgacgcatccggaactcaggctgctg
tacgaagaaggaaaaaagcgaaggaaacctaactatagtagcgttgacctctctgaggtg
gaatgggaagaccgagatgacgtgttgagaaatgctatggtgaatcgaaagacggggaag
ttttccatggaggtgaagaagacagtggacaaagggaaacgggttttggtgatgacaaat
gactactattatacagacatcaagggtactcctttcagtttaggtgtggcgctttccaga
ggtcatgggaaatatttcttccgagggaatgtaaccatcgaagaaggcctgcatgactta
gaacatcccgatgtgtccttggcagatgaatggtcctactgcaacactgacctacaccct
gagcaccgccatctgtctcagttagaagcgattaagctctacctaaaaggcaaagaacct
ctgctccagtgtgataaagaattgatccaagaagtcctttttgacgcggtggtgagtgcc
cccattgaagcgtattggaccagcctggccctcaacaaatctgaaaattctgacaagggc
gtggaggttgccttcctcggcactcgcacgggcctctccagaatcaacctgtttgtcggg
gctgagcagctcaccaatcaggacttcctgaaagctggcgacaaggagaacatttttaac
gcagaccatttccctctctggtaccgaagagccgctgagcagattccagggagcttcgtc
tactcgatcccgttcagcactggaccagtcaataaaagcaatgtggtgacagcgagtaca
tccatccagctcctggatgaacggaaatctcctgtggtggcagctgtaggcattcagatg
aaacttgaatttttccaaaggaagttctggactgccagcagacagtgtgcttccctggat
ggcaaatgctccatcagctgtgatgatgagactgtgaattgttacctcatagacaataat
ggatttattttggtgtctgaagactacacacagactggagacttttttggtgagatcgag
ggagctgtgatgaacaaattgctaacaatgggctcctttaaaagaattaccctttatgac
taccaagccatgtgtagagccaacaaggaaagcagcgatggcgcccatggcctcctggat
ccttataatgccttcctctctgcagtaaaatggatcatgacagaacttgtcttgttcctg
gtggaatttaacctctgcagttggtggcactccgatatgacagctaaagcccagaaattg
aaacagaccctggagccttgtgatactgaatatccagcattcgtctctgagcgcaccatc
aaggagactacagggaatattgcttgtgaagactgctccaagtcctttgtcatccagcaa
atcccaagcagcaacctgttcatggtggtggtggacagcagctgcctctgtgaatctgtg
gcccccatcaccatggcacccattgaaatcaggtataatgaatcccttaagtgtgaacgt
ctaaaggcccagaagatcagaaggcgcccagaatcttgtcatggcttccatcctgaggag
aatgcaagggagtgtgggggtgcaccgagtctcgaagcccagacagtcctccttctgctc
cctctgcttttgatgctcttctcaaggtga

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