KEGG   Pan troglodytes (chimpanzee): 469367Help
Entry
469367            CDS       T01005                                 

Gene name
PRKACB
Definition
(RefSeq) cAMP-dependent protein kinase catalytic subunit beta isoform X11
  KO
K04345  protein kinase A [EC:2.7.11.11]
Organism
ptr  Pan troglodytes (chimpanzee)
Pathway
ptr01522  Endocrine resistance
ptr04010  MAPK signaling pathway
ptr04014  Ras signaling pathway
ptr04020  Calcium signaling pathway
ptr04024  cAMP signaling pathway
ptr04062  Chemokine signaling pathway
ptr04114  Oocyte meiosis
ptr04140  Autophagy - animal
ptr04211  Longevity regulating pathway
ptr04213  Longevity regulating pathway - multiple species
ptr04261  Adrenergic signaling in cardiomyocytes
ptr04270  Vascular smooth muscle contraction
ptr04310  Wnt signaling pathway
ptr04340  Hedgehog signaling pathway
ptr04371  Apelin signaling pathway
ptr04530  Tight junction
ptr04540  Gap junction
ptr04611  Platelet activation
ptr04713  Circadian entrainment
ptr04714  Thermogenesis
ptr04720  Long-term potentiation
ptr04723  Retrograde endocannabinoid signaling
ptr04724  Glutamatergic synapse
ptr04725  Cholinergic synapse
ptr04726  Serotonergic synapse
ptr04727  GABAergic synapse
ptr04728  Dopaminergic synapse
ptr04740  Olfactory transduction
ptr04742  Taste transduction
ptr04750  Inflammatory mediator regulation of TRP channels
ptr04910  Insulin signaling pathway
ptr04911  Insulin secretion
ptr04912  GnRH signaling pathway
ptr04913  Ovarian steroidogenesis
ptr04914  Progesterone-mediated oocyte maturation
ptr04915  Estrogen signaling pathway
ptr04916  Melanogenesis
ptr04918  Thyroid hormone synthesis
ptr04919  Thyroid hormone signaling pathway
ptr04921  Oxytocin signaling pathway
ptr04922  Glucagon signaling pathway
ptr04923  Regulation of lipolysis in adipocytes
ptr04924  Renin secretion
ptr04925  Aldosterone synthesis and secretion
ptr04926  Relaxin signaling pathway
ptr04927  Cortisol synthesis and secretion
ptr04928  Parathyroid hormone synthesis, secretion and action
ptr04934  Cushing's syndrome
ptr04961  Endocrine and other factor-regulated calcium reabsorption
ptr04962  Vasopressin-regulated water reabsorption
ptr04970  Salivary secretion
ptr04971  Gastric acid secretion
ptr04976  Bile secretion
ptr05012  Parkinson's disease
ptr05020  Prion diseases
ptr05030  Cocaine addiction
ptr05031  Amphetamine addiction
ptr05032  Morphine addiction
ptr05146  Amoebiasis
ptr05165  Human papillomavirus infection
ptr05166  HTLV-I infection
ptr05169  Epstein-Barr virus infection
ptr05200  Pathways in cancer
ptr05203  Viral carcinogenesis
ptr05205  Proteoglycans in cancer
ptr05414  Dilated cardiomyopathy (DCM)
Module
ptr_M00695  cAMP signaling
Brite
KEGG Orthology (KO) [BR:ptr00001]
 Environmental Information Processing
  Signal transduction
   04014 Ras signaling pathway
    469367 (PRKACB)
   04010 MAPK signaling pathway
    469367 (PRKACB)
   04310 Wnt signaling pathway
    469367 (PRKACB)
   04340 Hedgehog signaling pathway
    469367 (PRKACB)
   04371 Apelin signaling pathway
    469367 (PRKACB)
   04020 Calcium signaling pathway
    469367 (PRKACB)
   04024 cAMP signaling pathway
    469367 (PRKACB)
 Cellular Processes
  Transport and catabolism
   04140 Autophagy - animal
    469367 (PRKACB)
  Cell growth and death
   04114 Oocyte meiosis
    469367 (PRKACB)
  Cellular community - eukaryotes
   04530 Tight junction
    469367 (PRKACB)
   04540 Gap junction
    469367 (PRKACB)
 Organismal Systems
  Immune system
   04611 Platelet activation
    469367 (PRKACB)
   04062 Chemokine signaling pathway
    469367 (PRKACB)
  Endocrine system
   04911 Insulin secretion
    469367 (PRKACB)
   04910 Insulin signaling pathway
    469367 (PRKACB)
   04922 Glucagon signaling pathway
    469367 (PRKACB)
   04923 Regulation of lipolysis in adipocyte
    469367 (PRKACB)
   04912 GnRH signaling pathway
    469367 (PRKACB)
   04913 Ovarian Steroidogenesis
    469367 (PRKACB)
   04915 Estrogen signaling pathway
    469367 (PRKACB)
   04914 Progesterone-mediated oocyte maturation
    469367 (PRKACB)
   04921 Oxytocin signaling pathway
    469367 (PRKACB)
   04926 Relaxin signaling pathway
    469367 (PRKACB)
   04918 Thyroid hormone synthesis
    469367 (PRKACB)
   04919 Thyroid hormone signaling pathway
    469367 (PRKACB)
   04928 Parathyroid hormone synthesis, secretion and action
    469367 (PRKACB)
   04916 Melanogenesis
    469367 (PRKACB)
   04924 Renin secretion
    469367 (PRKACB)
   04925 Aldosterone synthesis and secretion
    469367 (PRKACB)
   04927 Cortisol synthesis and secretion
    469367 (PRKACB)
  Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    469367 (PRKACB)
   04270 Vascular smooth muscle contraction
    469367 (PRKACB)
  Digestive system
   04970 Salivary secretion
    469367 (PRKACB)
   04971 Gastric acid secretion
    469367 (PRKACB)
   04976 Bile secretion
    469367 (PRKACB)
  Excretory system
   04962 Vasopressin-regulated water reabsorption
    469367 (PRKACB)
   04961 Endocrine and other factor-regulated calcium reabsorption
    469367 (PRKACB)
  Nervous system
   04724 Glutamatergic synapse
    469367 (PRKACB)
   04727 GABAergic synapse
    469367 (PRKACB)
   04725 Cholinergic synapse
    469367 (PRKACB)
   04728 Dopaminergic synapse
    469367 (PRKACB)
   04726 Serotonergic synapse
    469367 (PRKACB)
   04720 Long-term potentiation
    469367 (PRKACB)
   04723 Retrograde endocannabinoid signaling
    469367 (PRKACB)
  Sensory system
   04740 Olfactory transduction
    469367 (PRKACB)
   04742 Taste transduction
    469367 (PRKACB)
   04750 Inflammatory mediator regulation of TRP channels
    469367 (PRKACB)
  Aging
   04211 Longevity regulating pathway - mammal
    469367 (PRKACB)
   04213 Longevity regulating pathway - multiple species
    469367 (PRKACB)
  Environmental adaptation
   04713 Circadian entrainment
    469367 (PRKACB)
   04714 Thermogenesis
    469367 (PRKACB)
 Human Diseases
  Cancers
   05200 Pathways in cancer
    469367 (PRKACB)
   05205 Proteoglycans in cancer
    469367 (PRKACB)
   05203 Viral carcinogenesis
    469367 (PRKACB)
  Neurodegenerative diseases
   05012 Parkinson's disease
    469367 (PRKACB)
   05020 Prion diseases
    469367 (PRKACB)
  Substance dependence
   05030 Cocaine addiction
    469367 (PRKACB)
   05031 Amphetamine addiction
    469367 (PRKACB)
   05032 Morphine addiction
    469367 (PRKACB)
  Cardiovascular diseases
   05414 Dilated cardiomyopathy (DCM)
    469367 (PRKACB)
  Endocrine and metabolic diseases
   04934 Cushing's syndrome
    469367 (PRKACB)
  Infectious diseases
   05166 HTLV-I infection
    469367 (PRKACB)
   05169 Epstein-Barr virus infection
    469367 (PRKACB)
   05165 Human papillomavirus infection
    469367 (PRKACB)
   05146 Amoebiasis
    469367 (PRKACB)
  Drug resistance
   01522 Endocrine resistance
    469367 (PRKACB)
Enzymes [BR:ptr01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.11  cAMP-dependent protein kinase
     469367 (PRKACB)
Protein kinases [BR:ptr01001]
 Serine/threonine kinases: AGC group
  PKA family
   469367 (PRKACB)
Messenger RNA biogenesis [BR:ptr03019]
 Eukaryotic Type
  mRNA surveillance and transport factors
   mRNA cycle factors
    Common to processing body (P body) and stress granule
     469367 (PRKACB)
Chromosome and associated proteins [BR:ptr03036]
 Eukaryotic Type
  Centrosome formation and ciliogenesis proteins
   Kinases and associated factors
    469367 (PRKACB)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif
Pfam: Pkinase Pkinase_Tyr Kinase-like Haspin_kinase
Motif
Other DBs
NCBI-GeneID: 469367
NCBI-ProteinID: XP_001135693
Ensembl: ENSPTRG00000000899
UniProt: A0A2I3RRJ6
Position
1
AA seq 339 aa AA seqDB search
MGLLKEFLAKAKEDFLKKWENPTQNNAGLEDFERKKTLGTGSFGRVMLVKHKATEQYYAM
KILDKQKVVKLKQIEHTLNEKRILQAVNFPFLVRLEYAFKDNSNLYMVMEYVPGGEMFSH
LRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDHQGYIQVTDFGFAKRV
KGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIV
SGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVSDIKTHKWFATTDWIAIYQRKVE
APFIPKFRGSGDTSNFDDYEEEDIRVSITEKCAKEFGEF
NT seq 1020 nt NT seq  +upstreamnt  +downstreamnt
atgggattgttgaaagagtttctagccaaagccaaagaagactttttgaaaaaatgggag
aatccaactcagaataatgccggacttgaagattttgaaaggaaaaaaacccttggaaca
ggttcatttggaagagtcatgttggtaaaacacaaagccactgaacagtattatgccatg
aagatcttagataagcagaaggttgttaaactgaagcaaatagagcatactttgaatgag
aaaagaatattacaggcagtgaattttcctttccttgttcgactggagtatgcttttaag
gataattctaatttatacatggttatggaatatgtccctgggggtgaaatgttttcacat
ctaagaagaattggaaggttcagtgagccccatgcacggttctatgcagctcagatagtg
ctaacattcgagtacctccattcactagacctcatctacagagatctaaaacctgaaaat
ctcttaattgaccatcaaggctatatccaggtcacagactttgggtttgccaaaagagtt
aaaggcagaacttggacattatgtggaactccagagtatttggctccagaaataattctc
agcaagggctacaataaggcagtggattggtgggcattaggagtgctaatctatgaaatg
gcagctggctatcccccattctttgcagaccaaccaattcagatttatgaaaagattgtt
tctggaaaggtccgattcccatcccacttcagttcagatctcaaggaccttctacggaac
ctgctgcaggtggatttgaccaagagatttggaaatctaaagaatggtgtcagtgatata
aaaacccacaagtggtttgccacgacagattggattgctatttaccagaggaaggttgaa
gctccattcataccaaagtttagaggctctggagataccagcaactttgatgactatgaa
gaagaagatatccgtgtctctataacagaaaaatgtgcaaaagaatttggtgaattttaa

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