KEGG   Pan troglodytes (chimpanzee): 737923Help
Entry
737923            CDS       T01005                                 

Gene name
GCK
Definition
(RefSeq) glucokinase (hexokinase 4)
  KO
K12407  
glucokinase [EC:2.7.1.2]
Organism
ptr  Pan troglodytes (chimpanzee)
Pathway
Glycolysis / Gluconeogenesis
Galactose metabolism
Starch and sucrose metabolism
Amino sugar and nucleotide sugar metabolism
Butirosin and neomycin biosynthesis
Metabolic pathways
Biosynthesis of antibiotics
Carbon metabolism
Insulin signaling pathway
Insulin secretion
Prolactin signaling pathway
Glucagon signaling pathway
Type II diabetes mellitus
Maturity onset diabetes of the young
Central carbon metabolism in cancer
Module
Glycolysis (Embden-Meyerhof pathway), glucose => pyruvate
Nucleotide sugar biosynthesis, glucose => UDP-glucose
Brite
KEGG Orthology (KO) [BR:ptr00001]
 Metabolism
  Overview
   01200 Carbon metabolism
    737923 (GCK)
  Carbohydrate metabolism
   00010 Glycolysis / Gluconeogenesis
    737923 (GCK)
   00052 Galactose metabolism
    737923 (GCK)
   00500 Starch and sucrose metabolism
    737923 (GCK)
   00520 Amino sugar and nucleotide sugar metabolism
    737923 (GCK)
  Biosynthesis of other secondary metabolites
   00524 Butirosin and neomycin biosynthesis
    737923 (GCK)
 Organismal Systems
  Endocrine system
   04911 Insulin secretion
    737923 (GCK)
   04910 Insulin signaling pathway
    737923 (GCK)
   04922 Glucagon signaling pathway
    737923 (GCK)
   04917 Prolactin signaling pathway
    737923 (GCK)
 Human Diseases
  Cancers
   05230 Central carbon metabolism in cancer
    737923 (GCK)
  Endocrine and metabolic diseases
   04930 Type II diabetes mellitus
    737923 (GCK)
   04950 Maturity onset diabetes of the young
    737923 (GCK)
Enzymes [BR:ptr01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.1  Phosphotransferases with an alcohol group as acceptor
    2.7.1.2  glucokinase
     737923 (GCK)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif Motif
Other DBs
NCBI-ProteinID: 
NCBI-GI: 
NCBI-GeneID: 
Ensembl: 
Position
7
AA seq 462 aa AA seqDB search
MLTGVAVSDLSFVEQILAEFQLQEEDLKKVMRRMQKEMDRGLRLETHEEASVKMLPTYVR
STPEGSEVGDFLSLDLGGTNFRVMLVKVGEGEEGQWSVKTKHQMYSIPEDAMTGTAEMLF
DYISECISDFLDKHQMKHKKLPLGFTFSFPVRHEDIDKGILLNWTKGFKASGAEGNNVVG
LLRDAIKRRGDFEMDVVAMVNDTVATMISCYYEDHQCEVGMIVGTGCNACYMEEMQNVEL
VEGDEGRMCVNTEWGAFGDSGELDEFLLEYDRLVDESSANPGQQLYEKLIGGKYMGELVR
LVLLRLVDENLLFHGKASEQLRTRGAFETRFVSQVESDTGDRKQIYNILSTLGLRPSTTD
CDIVRRACESVSTRAAHMCSAGLAGVINRMRESRSEDVMRITVGVDGSVYKLHPSFKERF
HASVRRLTPSCEITFIESEEGSGRGAALVSAVACKKACMLGQ
NT seq 1389 nt NT seq  +upstreamnt  +downstreamnt
atgctcacgggagtggcagtatcagatctgagcttcgtagagcagatcctggcagagttc
cagctgcaggaggaggacctgaagaaggtgatgagacggatgcagaaggagatggaccgt
ggcctgaggctggagacccatgaagaggccagtgtgaagatgctgcccacctacgtgcgc
tccaccccagaaggctcagaagtcggggacttcctctccctggacctgggtggcactaac
ttcagggtgatgctggtgaaggtgggagaaggtgaggaggggcagtggagcgtgaagacc
aaacaccagatgtactccatccccgaggacgccatgaccggcactgctgagatgctcttc
gactacatctctgagtgcatctccgacttcctggacaagcatcagatgaagcacaagaag
ctgcccctgggcttcaccttctcctttcctgtgaggcacgaagacatcgataagggcatc
cttctcaactggaccaagggcttcaaggcctcaggagcagaagggaacaatgtcgtgggg
cttctgcgagacgctatcaaacggagaggggactttgaaatggatgtggtggcaatggtg
aatgacacggtggccacgatgatctcctgctactacgaagaccatcagtgcgaggtcggc
atgatcgtgggcacgggctgcaatgcctgctacatggaggagatgcagaatgtggagctg
gtggagggggacgagggccgcatgtgcgtcaataccgagtggggcgccttcggggactcc
ggcgagctggacgagttcctgctggagtatgaccgcctggtggacgagagctctgcaaac
cccggtcagcagctgtatgagaagctcataggtggcaagtacatgggcgagctggtgcgg
ctcgtgctgctcaggctcgtggacgaaaacctgctcttccacgggaaggcctccgagcag
ctgcgcacacgcggagccttcgagacgcgcttcgtgtcgcaggtggagagcgacacgggc
gaccgcaagcagatctacaacatcctgagcacgctggggctgcgaccctcgaccaccgac
tgcgacatcgtgcgccgcgcctgcgagagcgtgtctacgcgcgctgcgcacatgtgctcg
gcggggctggcgggcgtcatcaaccgcatgcgcgagagccgcagcgaggacgtaatgcgc
atcactgtgggcgtggatggctccgtgtacaagctgcaccccagcttcaaggagcggttc
catgccagcgtgcgcaggctgacgcccagctgcgagatcaccttcatcgagtcggaggag
ggcagtggccggggtgcggccctggtctcggcggtggcctgtaagaaggcctgtatgctg
ggccagtga

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