KEGG   Pan troglodytes (chimpanzee): 745709Help
Entry
745709            CDS       T01005                                 

Gene name
PPP1CA
Definition
protein phosphatase 1, catalytic subunit, alpha isozyme
Orthology
K06269  
serine/threonine-protein phosphatase PP1 catalytic subunit [EC:3.1.3.16]
Organism
ptr  Pan troglodytes (chimpanzee)
Pathway
mRNA surveillance pathway
cGMP-PKG signaling pathway
cAMP signaling pathway
Oocyte meiosis
Adrenergic signaling in cardiomyocytes
Vascular smooth muscle contraction
Hippo signaling pathway
Focal adhesion
Platelet activation
Long-term potentiation
Dopaminergic synapse
Inflammatory mediator regulation of TRP channels
Regulation of actin cytoskeleton
Insulin signaling pathway
Oxytocin signaling pathway
Amphetamine addiction
Alcoholism
Herpes simplex infection
Proteoglycans in cancer
Brite
KEGG Orthology (KO) [BR:ptr00001]
 Genetic Information Processing
  Translation
   03015 mRNA surveillance pathway
    745709 (PPP1CA)
 Environmental Information Processing
  Signal transduction
   04390 Hippo signaling pathway
    745709 (PPP1CA)
   04024 cAMP signaling pathway
    745709 (PPP1CA)
   04022 cGMP - PKG signaling pathway
    745709 (PPP1CA)
 Cellular Processes
  Cell motility
   04810 Regulation of actin cytoskeleton
    745709 (PPP1CA)
  Cell growth and death
   04114 Oocyte meiosis
    745709 (PPP1CA)
  Cellular commiunity
   04510 Focal adhesion
    745709 (PPP1CA)
 Organismal Systems
  Immune system
   04611 Platelet activation
    745709 (PPP1CA)
  Endocrine system
   04910 Insulin signaling pathway
    745709 (PPP1CA)
   04921 Oxytocin signaling pathway
    745709 (PPP1CA)
  Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    745709 (PPP1CA)
   04270 Vascular smooth muscle contraction
    745709 (PPP1CA)
  Nervous system
   04728 Dopaminergic synapse
    745709 (PPP1CA)
   04720 Long-term potentiation
    745709 (PPP1CA)
  Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    745709 (PPP1CA)
 Human Diseases
  Cancers
   05205 Proteoglycans in cancer
    745709 (PPP1CA)
  Substance dependence
   05031 Amphetamine addiction
    745709 (PPP1CA)
   05034 Alcoholism
    745709 (PPP1CA)
  Infectious diseases
   05168 Herpes simplex infection
    745709 (PPP1CA)
Enzymes [BR:ptr01000]
 3. Hydrolases
  3.1  Acting on ester bonds
   3.1.3  Phosphoric-monoester hydrolases
    3.1.3.16  protein-serine/threonine phosphatase
     745709 (PPP1CA)
Protein phosphatases and associated proteins [BR:ptr01009]
 Protein Ser/ Thr phosphatases
  Phosphoprotein phosphatases (PPPs)
   Protein phosphatase-1
    Catalytic subunits
     745709 (PPP1CA)
Transcription machinery [BR:ptr03021]
 Eukaryotic type
  RNA polymerase II system
   Other transcription-related factors
    Transcription termination factor
     745709 (PPP1CA)
Spliceosome [BR:ptr03041]
 Other splicing related proteins
  Spliceosome associated proteins (SAPs)
   Other SAPs
    745709 (PPP1CA)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif Motif
Other DBs
NCBI-GI: 
NCBI-GeneID: 
Ensembl: 
Position
11
AA seq 330 aa AA seqDB search
MSDSEKLNLDSIIGRLLEVQGSRPGKNVQLTENEIRGLCLKSREIFLSQPILLELEAPLK
ICGDIHGQYYDLLRLFEYGGFPPESNYLFLGDYVDRGKQSLETICLLLAYKIKYPENFFL
LRGNHECASINRIYGFYDECKRRYNIKLWKTFTDCFNCLPIAAIVDEKIFCCHGGLSPDL
QSMEQIRRIMRPTDVPDQGLLCDLLWSDPDKDVQGWGENDRGVSFTFGAEVVAKFLHKHD
LDLICRAHQVVEDGYEFFAKRQLVTLFSAPNYCGEFDNAGAMMSVDETLMCSFQILKPAD
KNKGKYGQFSGLNPGGRPITPPRNSAKAKK
NT seq 993 nt NT seq  +upstreamnt  +downstreamnt
atgtccgacagcgagaagctcaacctggactcgatcatcgggcgcctgctggaagtgcag
ggctcgcggcctggcaagaatgtacagctgacagagaacgagatccgcggtctgtgcctg
aaatcccgggagattttcctgagccagcccattcttctggagctggaggcacccctcaag
atctgcggtgacatacacggccagtactacgaccttctgcgactatttgagtatggcggt
ttccctcccgagagcaactacctctttctgggggactatgtggacaggggcaagcagtcc
ttggagaccatctgcctgctgctggcctataagatcaagtaccccgagaacttcttcctg
ctccgtgggaaccacgagtgtgccagcatcaaccgcatctatggtttctacgatgagtgc
aagagacgctacaacatcaaactgtggaaaaccttcactgactgcttcaactgcctgccc
atcgcggccatagtggacgaaaagatcttctgctgccacggaggcctgtccccggacctg
cagtctatggaacagattcggcggatcatgcggcccacagatgtgcctgaccagggcctg
ctgtgtgacctgctgtggtctgaccctgacaaggacgtgcagggctggggcgagaacgac
cgtggcgtctcttttacctttggagccgaggtggtggccaagttcctccacaagcacgac
ttggacctcatctgccgagcacaccaggtggtagaagacggctacgagttctttgccaag
cggcagctggtgacacttttctcagctcccaactactgtggcgagtttgacaatgctggc
gccatgatgagcgtggacgagaccctcatgtgctctttccagatcctcaagcccgccgac
aagaacaaggggaagtacgggcagttcagtggcctgaaccctggaggccgacccatcacc
ccaccccgcaattccgccaaagccaagaaataa

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