KEGG   Pan troglodytes (chimpanzee): 747077Help
Entry
747077            CDS       T01005                                 

Gene name
MAPK12
Definition
mitogen-activated protein kinase 12
Orthology
K04441  
p38 MAP kinase [EC:2.7.11.24]
Organism
ptr  Pan troglodytes (chimpanzee)
Pathway
MAPK signaling pathway
Rap1 signaling pathway
FoxO signaling pathway
Adrenergic signaling in cardiomyocytes
VEGF signaling pathway
Osteoclast differentiation
Platelet activation
Toll-like receptor signaling pathway
NOD-like receptor signaling pathway
RIG-I-like receptor signaling pathway
T cell receptor signaling pathway
Fc epsilon RI signaling pathway
TNF signaling pathway
Leukocyte transendothelial migration
Neurotrophin signaling pathway
Retrograde endocannabinoid signaling
Dopaminergic synapse
Inflammatory mediator regulation of TRP channels
GnRH signaling pathway
Progesterone-mediated oocyte maturation
Prolactin signaling pathway
Amyotrophic lateral sclerosis (ALS)
Salmonella infection
Pertussis
Leishmaniasis
Chagas disease (American trypanosomiasis)
Toxoplasmosis
Tuberculosis
Hepatitis C
Influenza A
Epstein-Barr virus infection
Proteoglycans in cancer
Brite
KEGG Orthology (KO) [BR:ptr00001]
 Environmental Information Processing
  Signal transduction
   04015 Rap1 signaling pathway
    747077 (MAPK12)
   04010 MAPK signaling pathway
    747077 (MAPK12)
   04370 VEGF signaling pathway
    747077 (MAPK12)
   04668 TNF signaling pathway
    747077 (MAPK12)
   04068 FoxO signaling pathway
    747077 (MAPK12)
 Organismal Systems
  Immune system
   04611 Platelet activation
    747077 (MAPK12)
   04620 Toll-like receptor signaling pathway
    747077 (MAPK12)
   04621 NOD-like receptor signaling pathway
    747077 (MAPK12)
   04622 RIG-I-like receptor signaling pathway
    747077 (MAPK12)
   04660 T cell receptor signaling pathway
    747077 (MAPK12)
   04664 Fc epsilon RI signaling pathway
    747077 (MAPK12)
   04670 Leukocyte transendothelial migration
    747077 (MAPK12)
  Endocrine system
   04912 GnRH signaling pathway
    747077 (MAPK12)
   04914 Progesterone-mediated oocyte maturation
    747077 (MAPK12)
   04917 Prolactin signaling pathway
    747077 (MAPK12)
  Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    747077 (MAPK12)
  Nervous system
   04728 Dopaminergic synapse
    747077 (MAPK12)
   04723 Retrograde endocannabinoid signaling
    747077 (MAPK12)
   04722 Neurotrophin signaling pathway
    747077 (MAPK12)
  Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    747077 (MAPK12)
  Development
   04380 Osteoclast differentiation
    747077 (MAPK12)
 Human Diseases
  Cancers
   05205 Proteoglycans in cancer
    747077 (MAPK12)
  Neurodegenerative diseases
   05014 Amyotrophic lateral sclerosis (ALS)
    747077 (MAPK12)
  Infectious diseases
   05132 Salmonella infection
    747077 (MAPK12)
   05133 Pertussis
    747077 (MAPK12)
   05152 Tuberculosis
    747077 (MAPK12)
   05164 Influenza A
    747077 (MAPK12)
   05160 Hepatitis C
    747077 (MAPK12)
   05169 Epstein-Barr virus infection
    747077 (MAPK12)
   05145 Toxoplasmosis
    747077 (MAPK12)
   05140 Leishmaniasis
    747077 (MAPK12)
   05142 Chagas disease (American trypanosomiasis)
    747077 (MAPK12)
Enzymes [BR:ptr01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.24  mitogen-activated protein kinase
     747077 (MAPK12)
Protein kinases [BR:ptr01001]
 Serine/threonine protein kinases: CMGC group
  MAPK family [OT]
   747077 (MAPK12)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif Motif
Other DBs
NCBI-GI: 
NCBI-GeneID: 
Position
22
AA seq 437 aa AA seqDB search
MSGPRAGFYRQELNKTVWEVPQRLQGLRPVGSGAYGSVWPEAWGVTAGVRARTYIQSLPP
MPQKDLSSIFRGANPLAIDLLGRMLVLDSDQRVSAAEALAHAYFSQYHDPEDEPEAEPYD
ESVEAKERTLEEWKAPGRTQPLNSAPQPGPDQGTRLGQAQGILQISLQALPPAMKPAVIG
LLDVFTPDETLDDFTDFYLVMPFMGTDLGKLMKHEKLGEDRIQFLVYQMLKGLRYIHAAG
IIHRDLKPGNLAVNEDCELKILDFGLARQADSEMTGYVVTRWYRAPEVILNWMRYTQTVD
IWSVGCIMAEMITGKTLFKGSDHLDQLKEIMKVTGTPPAEFVQRLQSDEAKNYMKGLPEL
EKKDFASILTNASPLAVNLLEKMLVLDAEQRVTAAEALAHPYFESLHDTEDEPQVQKYDD
SFDDVDRTLDEWKRFCC
NT seq 1314 nt NT seq  +upstreamnt  +downstreamnt
atgtcgggccctcgcgccggcttctaccggcaggagctgaacaagaccgtgtgggaggtg
ccgcagcggctgcaggggctgcgcccggtgggctccggcgcctacggctccgtctggcct
gaggcctggggggtcacagctggcgtgagggcccggacatatatccagtccctgcccccc
atgccccagaaggacctgagcagcatcttccgtggagccaaccccctggccatagacctc
cttggaaggatgctggtgctggacagtgaccagagggtcagtgcggctgaggcactggcc
cacgcctacttcagccagtaccacgaccccgaggatgagccagaggccgagccatatgat
gagagcgttgaggccaaggagcgcacgctggaggagtggaaggccccgggaaggactcag
ccccttaactcggcgcctcagccaggccctgatcaggggacacgacttggccaggcccag
gggatcctccagatctcactccaagccttgcccccagccatgaagcccgcggtgatcggg
ctgctggacgtattcactcctgatgagaccctggatgacttcacggacttttacctggtg
atgccgttcatgggcaccgacctgggcaagctcatgaaacatgagaagctaggcgaggac
cggatccagttcctcgtgtaccagatgctgaaggggctgaggtatatccacgctgctggc
atcatccacagagacctgaagcccggcaacctggctgtgaacgaagactgtgagctgaag
atcctggacttcggcctggccaggcaggcagacagtgagatgactgggtacgtggtgacc
cggtggtaccgggctcccgaggtcatcttgaattggatgcgctacacgcagacggtggac
atctggtctgtgggctgcatcatggcggagatgatcacaggcaagacgctgttcaagggc
agcgaccacctggaccagctgaaggagatcatgaaggtgacggggacgcctccggctgag
tttgtgcagcggctgcagagcgatgaggccaagaactacatgaagggcctccccgaattg
gagaagaaggattttgcctctatcctgaccaatgcaagccctctggctgtgaacctcctg
gagaagatgctggtgctggacgcggagcagcgggtgacagcagccgaggcgctggcccat
ccctacttcgagtccctgcacgacacggaagatgagccccaggtccagaagtatgatgac
tcctttgacgacgtggaccgcacactggatgaatggaagcgtttctgctgctag

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