KEGG   Pan troglodytes (chimpanzee): 748998
Entry
748998            CDS       T01005                                 
Symbol
CYP11A1
Name
(RefSeq) cholesterol side-chain cleavage enzyme, mitochondrial
  KO
K00498  cholesterol monooxygenase (side-chain-cleaving) [EC:1.14.15.6]
Organism
ptr  Pan troglodytes (chimpanzee)
Pathway
ptr00140  Steroid hormone biosynthesis
ptr01100  Metabolic pathways
ptr04913  Ovarian steroidogenesis
ptr04925  Aldosterone synthesis and secretion
ptr04927  Cortisol synthesis and secretion
ptr04934  Cushing syndrome
Module
ptr_M00107  Steroid hormone biosynthesis, cholesterol => pregnenolone => progesterone
Brite
KEGG Orthology (KO) [BR:ptr00001]
 09100 Metabolism
  09103 Lipid metabolism
   00140 Steroid hormone biosynthesis
    748998 (CYP11A1)
 09150 Organismal Systems
  09152 Endocrine system
   04913 Ovarian steroidogenesis
    748998 (CYP11A1)
   04925 Aldosterone synthesis and secretion
    748998 (CYP11A1)
   04927 Cortisol synthesis and secretion
    748998 (CYP11A1)
 09160 Human Diseases
  09167 Endocrine and metabolic disease
   04934 Cushing syndrome
    748998 (CYP11A1)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   00199 Cytochrome P450 [BR:ptr00199]
    748998 (CYP11A1)
Enzymes [BR:ptr01000]
 1. Oxidoreductases
  1.14  Acting on paired donors, with incorporation or reduction of molecular oxygen
   1.14.15  With reduced iron-sulfur protein as one donor, and incorporation of one atom of oxygen into the other donor
    1.14.15.6  cholesterol monooxygenase (side-chain-cleaving)
     748998 (CYP11A1)
Cytochrome P450 [BR:ptr00199]
 Cytochrome P450, animal type
  CYP11 family
   748998 (CYP11A1)
SSDB
Motif
Pfam: p450
Other DBs
NCBI-GeneID: 748998
NCBI-ProteinID: NP_001267337
Ensembl: ENSPTRG00000046983
UniProt: G2HDT8 A0A6D2WK84
Position
15:complement(52740563..52770496)
AA seq 521 aa
MLAKGLPPRSVLVKGCQTFLSAPREGLGRLRVPTGEGAGISTRSPRPFNEIPSPGDNGWL
NLYHFWRETGTHKVHLHHVQNFQKYGPIYREKLGNVESVYVIDPEDVALLFKSEGPNPER
FLIPPWVAYHQYYQRPIGVLLKKSAAWKKDRVALNQEVMAPEATKNFLPLLDAVSRDFVS
VLHRRIKKAGSGNYSGDISDDLFRFAFESITNVIFGERQGMLEEVVNPEAQRFIDAIYQM
FHTSVPMLNLPPDLFRLFRTKTWKDHVAAWDVIFSKADIYTQNFYWELRQKGSVHHDYRG
ILYRLLGDSKMSFEDIKANVTEMLAGGVDTTSMTLQWHLYEMARNLKVQDMLRAEVLAAR
RQAQGDMATMLQLVPLLKASIKETLRLHPISVTLQRYLVNDLVLRDYMIPAKTLVQVAIY
ALGREPTFFFDPENFDPTRWLSKDKNVTYFRNLGFGWGVRQCLGRRIAELEMTIFLINML
ENFRVEIQHLSDVGTTFNLILMPEKPISFTFWPFNQEATQQ
NT seq 1566 nt   +upstreamnt  +downstreamnt
atgctggccaagggtcttcccccacgctcagtcctggtcaaaggctgccagacctttctg
agtgcccccagggaggggctggggcgtctcagggtgcccactggcgagggagctggcatc
tccacccgcagtcctcgccccttcaatgagatcccctctcctggtgacaatggctggcta
aacctgtatcatttctggagggagacgggcacacacaaagtccaccttcaccatgtccag
aatttccagaagtatggcccgatttacagggagaagctcggcaacgtggagtcggtttat
gtcatcgaccctgaagatgtggcccttctctttaagtctgagggccccaacccagaacga
ttcctcatcccgccctgggtcgcctatcaccagtattaccagagacccataggagtcctg
ttgaagaagtcggcagcctggaagaaagaccgggtggccctgaaccaggaggtgatggct
ccagaggccaccaagaactttttgcccctgttggatgcagtatctcgggacttcgtcagt
gtcctgcacaggcgcatcaagaaggcgggctccggaaattactcgggggacatcagtgat
gacctgttccgctttgcttttgagtccatcactaacgtcatttttggggagcgccagggg
atgctggaagaagtagtgaaccccgaggcccagcgattcattgatgccatctaccagatg
ttccacaccagcgtccccatgctcaaccttcccccagacctgttccgtctgttcagaacc
aagacctggaaggaccatgtggctgcatgggacgtgattttcagtaaagctgacatatac
acccagaacttctactgggaattgagacagaaaggaagtgttcaccacgattaccgtggc
atcctctacagactcctgggagacagcaagatgtccttcgaggacatcaaggccaacgtc
acggagatgctggcaggaggggtggacacgacgtccatgaccctgcagtggcacttgtac
gagatggcacgcaacctgaaggtgcaggatatgctgcgggcagaggtcttggctgcgcgg
cgccaggcccagggagacatggccacgatgctacagctggtccccctcctcaaagccagc
atcaaggagacactaagacttcaccccatctccgtgaccctgcagagatatcttgtaaat
gacttggttcttcgagattacatgattcctgccaagacactggtgcaagtggccatctat
gctttgggccgagagcccaccttcttcttcgacccggaaaattttgacccaacccgatgg
ctgagcaaagacaagaacgtcacctacttccggaacttgggctttggctggggtgtgcgg
cagtgtctgggacggcggatcgctgagctagagatgaccatcttcctcatcaatatgctg
gagaacttcagagttgaaatccaacacctcagcgatgtgggcaccacattcaacctcatt
ctgatgcctgaaaagcccatctccttcaccttctggccctttaaccaggaagcaacccag
cagtga

  All links  
Ontology (3)   
   KEGG BRITE (3)   
Pathway (7)   
   KEGG PATHWAY (6)   
   KEGG MODULE (1)   
Chemical substance (13)   
   KEGG COMPOUND (13)   
Chemical reaction (7)   
   KEGG ENZYME (1)   
   KEGG REACTION (6)   
Genome (1)   
   KEGG GENOME (1)   
Gene (5)   
   KEGG ORTHOLOGY (1)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   Ensembl (1)   
   OC (1)   
Protein sequence (7)   
   UniProt (2)   
   RefSeq(pep) (5)   
DNA sequence (9)   
   RefSeq(nuc) (5)   
   GenBank (2)   
   EMBL (2)   
Protein domain (1)   
   Pfam (1)   
All databases (53)   

Download RDF
DBGET integrated database retrieval system