KEGG   Rhinopithecus bieti (black snub-nosed monkey): 108521233
Entry
108521233         CDS       T04641                                 
Symbol
PLCE1
Name
(RefSeq) 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase epsilon-1
  KO
K05860  phosphatidylinositol phospholipase C, epsilon [EC:3.1.4.11]
Organism
rbb  Rhinopithecus bieti (black snub-nosed monkey)
Pathway
rbb00562  Inositol phosphate metabolism
rbb01100  Metabolic pathways
rbb04014  Ras signaling pathway
rbb04015  Rap1 signaling pathway
rbb04020  Calcium signaling pathway
rbb04024  cAMP signaling pathway
rbb04070  Phosphatidylinositol signaling system
rbb04919  Thyroid hormone signaling pathway
rbb04933  AGE-RAGE signaling pathway in diabetic complications
rbb05205  Proteoglycans in cancer
Module
rbb_M00130  Inositol phosphate metabolism, PI=> PIP2 => Ins(1,4,5)P3 => Ins(1,3,4,5)P4
Brite
KEGG Orthology (KO) [BR:rbb00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00562 Inositol phosphate metabolism
    108521233 (PLCE1)
 09130 Environmental Information Processing
  09132 Signal transduction
   04014 Ras signaling pathway
    108521233 (PLCE1)
   04015 Rap1 signaling pathway
    108521233 (PLCE1)
   04020 Calcium signaling pathway
    108521233 (PLCE1)
   04070 Phosphatidylinositol signaling system
    108521233 (PLCE1)
   04024 cAMP signaling pathway
    108521233 (PLCE1)
 09150 Organismal Systems
  09152 Endocrine system
   04919 Thyroid hormone signaling pathway
    108521233 (PLCE1)
 09160 Human Diseases
  09161 Cancer: overview
   05205 Proteoglycans in cancer
    108521233 (PLCE1)
  09167 Endocrine and metabolic disease
   04933 AGE-RAGE signaling pathway in diabetic complications
    108521233 (PLCE1)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:rbb04131]
    108521233 (PLCE1)
Enzymes [BR:rbb01000]
 3. Hydrolases
  3.1  Acting on ester bonds
   3.1.4  Phosphoric-diester hydrolases
    3.1.4.11  phosphoinositide phospholipase C
     108521233 (PLCE1)
Membrane trafficking [BR:rbb04131]
 Exocytosis
  Calcium ion-dependent exocytosis
   Phospholipases
    108521233 (PLCE1)
 Endocytosis
  Macropinocytosis
   Phospholipase C
    108521233 (PLCE1)
SSDB
Motif
Pfam: PI-PLC-X PI-PLC-Y RasGEF RA EF-hand_like GDPD
Other DBs
NCBI-GeneID: 108521233
NCBI-ProteinID: XP_017716455
Position
Unknown
AA seq 1765 aa
MEEGIRDCGLPGVEERQPGPSVANSNTLPSSSAGISKELIDLQPLIQFPEEVASILMEQE
QSIYRRVLPVDYLCFLTRDLGTPECQRSLPCLKASISASILTTQNGEHNALEDLVMRFNE
VSSWVTWLILTAGSMEEKREVFSYLVHVAKCCWNMGNYNAVMEFLAGLRSRKVLKMWQFM
DQSDIETMRSLKDAMAQHESSCEYRKVVTRALHIPGCKVVPFCGVFLKELCEVLDGASGL
MKICPRYNSQEETLEFVADYSGQDNFLQRVGQNGLKNSEKESTVNSIFQVIRSCSRSLET
DEEDSPSEGNSSRKSSLKDKSRWQFIIGDLLDSDNDIFEQSKEYDSHGSEDSQKAFDHGT
ELIPWYVLSIQADVHQFLLQGATVIHYDQDTHLSARCFLQLQPDNSTLTWVKPTTASPAS
TKAKLGVLYNTAEPGKFPLLGNAGLSGLTEGVLDLFAVKAVYMGHPGIDIHTVCVQNKLG
SMFLSETGVTLLYGLQTTDNRLLHFVAPKHTAKMLFSGLLELTRAVRKMRKFPDQRQQWL
RKQYVSLYQEDGRYEGPTLAHAVELFGGRRWSARNPSPGTSAKNAEKPSMQRNNTLGIST
TKKKKKILMRGESGEATDDEMATRKAKMHKECRSRSGSDPQDINEQEESEVNTIASPPNP
LPSRRAHSLTTAGSPNLAAGTSSPIRPVSSPVLPSSNKSPSSAWSSSSWHGRIKGGMKGF
QSFMVSDSNMSFVEFVELFKSFSVRSRKDLKDLFDVYAVPCSRSGSESAPLYTNLTIDEN
TSDLQPDLDLLTRNVSDLGLFIKSKQQLSDNQRQISDAIAAASIVTNGTGIESTSLGIFG
VGILQLNDFLVNCQGEHCTYDEILSIIQKFEPNISMCHQGLMSFEGFARFLMDKENFASK
NDESQENIKELQLPLSYYYIESSHNTYLTGHQLKGESSVELYSQVLLQGCRSVELDCWDG
DDGMPIIYHGHTLTTKIPFKEVVEAIDRSAFINSDLPIIISIENHCSLPQQRKMAEIFKT
VFGEKLVAKFLFETDFSDDPMLPSPDQLRRKVLLKNKKLKAHQTPVDILKQKAHQLASMQ
AQAYNGGNANPPPANNEEEEDEEDEYDYDYESLSDDNILEDRPENKSCNDKLQFEYSEEI
PKRIKKADNSAYNKGKVYDMELGEEFYLDQNKKESRQIAPELSDLVIYCQAVKFPGLSTL
NASGSNRGKERKSRKSIFGNNPGRMSPGETASFNKTSGKSSCEGIRQTWEESSSPLNPTT
SLSAIIRTPKCYHISSLNENAAKRLCRRYSQKLIQHTACQLLRTYPAATRIDSSNPNPIM
FWLHGIQLVALNYQTDDLPLHLNAAMFEANGGCGYVLKPPVLWDKNCPMYQKFSPLERDL
DSMDPVVYSLTIVSGPGRGAPVWLCHPGWSAVERLTVSLSNMLPGYRHLQLRNLHNEVLE
ISSLFINSRRMEENSSGSTMSASSMFNTEERKCLQTHRVTVHGVPGPEPFTVFTINGGTK
AKQLLQQILTTEQDIKPVTTDYFLMEEKYFISKEKNECRKQPFQRAIGPEEEIMQILSSW
FPEEGYVGRIVLKTQQENLEEKNTVQDDKEVILSSEEESFFVQVHDVSPEQPRTVIKAPR
VSTAQDVIQQTLCKAKYSYSILSNPNPSDYVLLEEVVKDTTNKKSTTPKSSQRVLLDQEC
VFQAQSKWKGAGKFILKLKEQVQASREDKKKGISFASELKKLTKSTKQARGLTSPSQLLT
SESIQTKEEKPVGGLSSNDTMDYRQ
NT seq 5298 nt   +upstreamnt  +downstreamnt
atggaagaaggaattagggactgtgggctacctggtgtagaagaacgccagccaggcccc
tctgtggccaattccaacaccctcccttcaagttcagctgggatcagcaaggagctgatc
gatctgcagcctctcatccagttcccagaggaagtcgccagcatcctgatggagcaggag
cagagtatttaccgcagggtcttgccggtcgactacctttgcttcttaacacgggacttg
ggcactcccgaatgccagaggtccctgccctgcctcaaagcatccatctcagcatcaatt
cttaccactcagaatggagagcacaatgcccttgaagatctggtgatgaggtttaatgag
gtgagctcctgggtgacgtggctgatcctcacggcaggctccatggaggagaagcgagaa
gtcttttcatatttggtgcatgtggccaaatgctgctggaacatgggcaactacaacgct
gtcatggagttcttggctggcctcaggtcaagaaaagttttaaaaatgtggcagtttatg
gaccagtctgatattgagaccatgaggagcctgaaggatgctatggcccagcatgagtcc
tcttgtgagtacagaaaggtggtgacacgtgccctgcacatccctggctgtaaggtggtt
ccgttctgtggagtgtttctgaaggagctctgtgaagtgcttgacggcgcctctggcctc
atgaagatatgcccgcggtacaattcccaagaagaaactttagagtttgtagcagattac
agtggacaagataatttcttacaacgagtgggacaaaatggcttaaagaattcggagaaa
gagtccactgtcaacagcatctttcaggtcatccggagctgcagtcgaagtctggagaca
gatgaggaggacagccccagtgaagggaacagctccaggaaaagttccttgaaggataaa
agccgatggcagtttataattggagatttgttggattcagacaatgatatctttgagcaa
tccaaagaatacgactctcatggttcagaggactcacagaaggcctttgaccatgggacg
gagctcatcccgtggtatgtgctgtccatccaagccgatgtgcaccagttcctgctgcag
ggggccacggtcatccactatgaccaggacacacacctctctgcccgatgcttcctccag
cttcagcctgacaatagcaccttgacctgggtaaagcccacaactgcctccccagctagc
actaaagcaaaacttggtgtactttataacacagctgagcctggaaaattcccactactg
ggcaatgctggattaagtggcctgacggaaggggtcttggatctttttgcagtgaaggct
gtatacatgggccaccctggcattgatatacacactgtgtgtgttcagaacaaactgggt
agcatgttcctgtcagagactggtgtgacactgctctatgggcttcagaccacggacaat
agattattgcacttcgtggcaccaaagcacacagctaaaatgctcttcagcggattgttg
gaactcactagagctgtgagaaagatgaggaaattccctgaccaaagacagcagtggctg
cggaaacagtacgtcagcctctatcaggaggatggacggtatgaaggcccaactttggct
catgctgtggagttgtttggtggcagacgatggagtgctcgaaaccccagccccggcaca
tctgcaaagaatgctgagaagcccagtatgcagagaaacaacaccctgggcataagcact
accaagaaaaagaagaaaatcctcatgaggggtgagagtggagaggcaactgacgatgag
atggcaacccgaaaggccaagatgcacaaagagtgtcgaagccggagtggttctgatcct
caagacattaatgaacaagaagaatcggaggtgaataccatcgctagcccgccaaacccc
ctcccttccagaagagcccactctttgaccacagctgggtcccccaacttggctgccggg
acgtcatctcccatcaggccagtgtcctcccctgtgctgccttcttcaaacaagagcccg
tccagtgcttggagcagtagtagctggcatgggcggatcaaaggcggcatgaagggattt
cagagcttcatggtttcagacagcaacatgagttttgttgaatttgttgagctgttcaaa
tcattcagtgtcaggagccgcaaggacctgaaggatctgtttgatgtctacgcagtgccc
tgcagccgatctggatccgagtcagccccgctctacaccaacctgacgattgatgaaaac
accagcgatcttcagcctgacctagatctgttgaccagaaatgtctcagatttggggttg
ttcatcaagagtaaacagcagctatcggacaaccagaggcagatatctgatgccattgct
gctgcaagcatcgtgacaaatggcactgggattgagagcacatctctgggcattttcggg
gtgggcatacttcagctcaatgatttcctcgtgaattgccaaggagaacactgcacttat
gatgaaatcctcagcatcatccagaagtttgaacctaacatcagtatgtgtcatcaggga
ctaatgtcatttgaagggtttgcaaggtttctgatggataaagaaaattttgcctcaaaa
aatgatgagtcacaggagaacattaaagaactacagctacccctctcatactattacatc
gaatcttcgcacaatacctacctcacgggccatcagctcaaaggagaatcctcagtagaa
ctctacagccaggtcctcttgcaaggctgtcgaagtgtagaattggactgctgggacgga
gacgatgggatgcccatcatttatcatggacatacactgacaaccaagatccccttcaag
gaagtggtcgaagccattgatcgcagtgccttcatcaactctgacctgccaatcatcata
tcgattgagaatcactgttcattgcctcagcaacgaaaaatggcagaaattttcaagact
gtgtttggagaaaagctggtggctaaattcttatttgagactgatttctcagatgatcca
atgcttccttcacctgaccaactcagaaggaaagtgcttcttaaaaacaagaagctaaaa
gcccatcagacgccagtggatatcttaaagcaaaaggctcatcagttagcatctatgcaa
gcgcaggcttataatggtgggaatgccaaccccccacctgccaataatgaggaagaggaa
gatgaggaggacgaatatgattatgactatgaatccctttctgatgacaacattctggaa
gacagacctgaaaataaatcatgtaatgacaagcttcagtttgagtatagtgaagaaatc
cccaagaggataaagaaggcagataactctgcttacaacaaaggaaaggtttatgatatg
gaactgggagaagaattttatcttgatcagaataaaaaggaaagcagacagattgcacca
gagctttctgaccttgtaatctattgtcaagcagtaaaatttccaggactgtcaactcta
aatgcatctggctctaacagaggaaaggaaaggaaaagcaggaagtccatttttggcaac
aatccgggcagaatgagcccaggggagacagcatcatttaacaaaacatctggaaaaagt
tcctgtgaaggcattcgacagacctgggaggaatcttcttcccctctcaacccaaccaca
tccctcagtgctatcattagaactcctaaatgttatcatatctcgtcgctgaatgaaaat
gccgccaaacgtctgtgtcgcaggtattctcagaaactgatccagcataccgcctgtcag
ctgctgagaacttaccctgctgccacccgcatcgactcctccaacccgaaccccatcatg
ttctggctccatgggatacagctcgtggcactcaactaccagaccgatgatctcccttta
catttaaatgctgcaatgtttgaggcaaatggtggttgtggttatgttttgaaacctcca
gttctgtgggacaagaactgcccgatgtatcagaagttttctccactggaaagagatctg
gacagcatggatcctgtagtctattctttaactattgtctctggtccgggaagaggggcc
ccagtctggctgtgtcacccaggctggagtgcagtggagcgattgacagtttccctttct
aacatgctcccaggatatcgacatcttcagctgcgaaaccttcacaatgaagtcttggaa
atctctagtctattcattaacagcagaaggatggaagaaaattcctctggcagtaccatg
tcagcctcttcgatgtttaatacagaagaaagaaaatgtttgcagactcacagagtcacg
gtgcatggggtcccagggccagagccctttactgttttcactattaatggaggcaccaag
gcaaagcagcttctgcagcaaattctgacaactgaacaagacatcaaacctgttaccaca
gactattttttgatggaagaaaaatattttatatctaaagaaaagaatgaatgtaggaaa
caaccattccagagagccattggtccagaagaggagatcatgcaaattttaagcagctgg
tttccagaagagggatatgtgggcaggattgtcttaaaaacccagcaggaaaacctagaa
gagaaaaacactgttcaagatgacaaagaagtgatcttgagctctgaggaggagagtttc
tttgtccaagtgcatgatgtttctccagagcaacctcgaacagtcatcaaagcaccccgc
gtcagcaccgcacaggatgtcattcagcagaccttatgcaaagccaaatattcctacagc
atcctgagcaaccccaatccgagtgactatgtgcttctggaagaggtggtgaaagacact
accaacaagaagtctaccacacccaagtcctctcagcgggtccttctggatcaggagtgt
gtgtttcaagcccaaagcaagtggaaaggtgcaggaaaattcatccttaagctaaaggag
caagtgcaggcatctcgagaagataaaaagaaaggcatttcttttgcaagtgaactcaag
aagctcaccaagtcaactaaacaggcccgaggacttacatcaccttctcagctcttgacc
tcagaaagtatccaaaccaaggaggagaaacctgtgggtggcctgtcctccaatgacaca
atggattaccgacagtga

  All links  
Ontology (3)   
   KEGG BRITE (3)   
Pathway (11)   
   KEGG PATHWAY (10)   
   KEGG MODULE (1)   
Chemical substance (8)   
   KEGG COMPOUND (8)   
Chemical reaction (4)   
   KEGG ENZYME (1)   
   KEGG REACTION (3)   
Genome (1)   
   KEGG GENOME (1)   
Gene (4)   
   KEGG ORTHOLOGY (1)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   OC (1)   
Protein sequence (1)   
   RefSeq(pep) (1)   
DNA sequence (1)   
   RefSeq(nuc) (1)   
Protein domain (6)   
   Pfam (6)   
All databases (39)   

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