KEGG   Ricinus communis (castor bean): RCOM_1447960Help
Entry
RCOM_1447960      CDS       T01087                                 

Definition
bifunctional dihydrofolate reductase-thymidylate synthase, putative (EC:1.5.1.3 2.1.1.45)
Orthology
K13998  
dihydrofolate reductase / thymidylate synthase [EC:1.5.1.3 2.1.1.45]
Organism
rcu  Ricinus communis (castor bean)
Pathway
Pyrimidine metabolism
One carbon pool by folate
Folate biosynthesis
Metabolic pathways
Module
Tetrahydrofolate biosynthesis, GTP => THF
Brite
KEGG Orthology (KO) [BR:rcu00001]
 Metabolism
  Nucleotide metabolism
   00240 Pyrimidine metabolism
    RCOM_1447960
  Metabolism of cofactors and vitamins
   00790 Folate biosynthesis
    RCOM_1447960
   00670 One carbon pool by folate
    RCOM_1447960
Enzymes [BR:rcu01000]
 1. Oxidoreductases
  1.5  Acting on the CH-NH group of donors
   1.5.1  With NAD+ or NADP+ as acceptor
    1.5.1.3  dihydrofolate reductase
     RCOM_1447960
 2. Transferases
  2.1  Transferring one-carbon groups
   2.1.1  Methyltransferases
    2.1.1.45  thymidylate synthase
     RCOM_1447960
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif Motif
Other DBs
NCBI-GI: 
NCBI-GeneID: 
UniProt: 
AA seq 528 aa AA seqDB search
MAGDTKANLSNGNANIEQHDPRRTYQVVVAATRDMGIGKDGKLPWRLPSDLKFFKDVTLT
TTDSGKKNAVIMGRKTWESIPLEHRPLPGRLNVVLTRSGSFDIATAENVVMCGSFASALE
LLAASPYCLSIEKVYVIGGGQILREALNAPGCDAVHITEIETSFDCDTFIPAIDSSIFHP
WYLSFPMVENNIRYSFATYVRVRSSAVESNGHDSGLSSESSSENSKFDVKKFSFLPKMVF
DRHEEFLYLRLVQEIISDGILKDDRTGTGTLSKFGCQVRFNLRKTFPLLTTKKVFWRGVV
EELLWFISGSTNAKVLQEKGIHIWDGNASRDYLDSIGLKNREEGDLGPVYGFQWRHFGAR
YTDMHADYTGQGFDQLLDVVNKIKNNPDDRRIILSAWNPSDLKLMALPPCHMFAQFYVAN
GELSCQMYQRSADMGLGVPFNIASYGLLTCIIAHVCDLVPGDFVHVIGDTHVYRTHVRPL
QEQLQKLPKPFPILKINPEKKNIDSFVAADFKLIGYDPHHKIEMKMAV
NT seq 1587 nt NT seq  +upstreamnt  +downstreamnt
atggctggtgatacgaaggcaaatctttctaatggtaatgctaatatagagcagcatgat
ccaagaagaacttaccaagttgttgtggctgcaactagggatatgggtattgggaaggat
gggaaacttccatggagattaccttctgatctcaaattttttaaggatgttactttgact
actactgattctgggaaaaagaatgctgttataatgggtagaaaaacatgggaaagtatt
cctctagagcatcgacctcttcctggtcgtctgaatgttgttttgactcgatcaggcagt
tttgatattgctactgctgagaatgttgtgatgtgtggaagctttgcttctgctttggaa
ttattggctgcttctccatattgtctctcaatcgagaaagtatatgtcataggaggaggc
caaattttaagggaagctcttaatgcacctggatgtgatgctgtccacattacagaaatt
gagacaagctttgattgtgatactttcattcctgcaattgattcttctatatttcatcct
tggtatttatcctttcccatggtagaaaataacatacgatattcatttgcaacttatgtt
cgagttaggagctctgcagttgaatccaatggtcacgatagtggtctgagctctgaaagc
agttcagaaaatagtaagttcgatgtaaaaaagttttctttccttcctaagatggttttt
gacagacacgaggagttcttgtatctgagacttgttcaagaaatcatctctgatggcatc
ttgaaggatgacagaactggaactggtactttatcaaaatttgggtgtcaggtgcggttc
aacttgcgaaaaacttttccgcttcttacaacaaagaaagtattctggcgaggtgttgtt
gaagaactcctgtggttcattagtggttcaacaaatgccaaggtccttcaggaaaaggga
attcatatttgggatggcaatgcatccagggattacctcgatagtattgggttgaagaac
agagaggagggtgacctgggacctgtttatggattccagtggagacactttggtgctagg
tatactgacatgcatgctgactacactggtcaaggatttgatcagttgttagacgttgtt
aacaagattaagaataatccagatgatcgtcgaattatcctttcagcttggaatccctct
gatctgaaattgatggcactacctccctgtcatatgtttgctcagttctatgtagcaaac
ggggagttatcatgtcaaatgtatcagcgatctgctgacatgggactgggtgtgccattc
aacattgcatcttatggtctcttgacatgcataattgctcatgtttgtgatctcgttcct
ggtgattttgttcatgtgatcggggatactcatgtttatcgcactcatgttaggcctctc
caggagcagcttcagaaactcccaaaaccttttccaatattgaagatcaacccagagaaa
aagaacatagattctttcgtggcagctgattttaaactcataggatatgatcctcaccac
aaaattgaaatgaaaatggcagtataa

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