KEGG   Ricinus communis (castor bean): RCOM_1595270Help
Entry
RCOM_1595270      CDS       T01087                                 

Definition
bifunctional dihydrofolate reductase-thymidylate synthase, putative (EC:1.5.1.3 2.1.1.45)
Orthology
K13998  
dihydrofolate reductase / thymidylate synthase [EC:1.5.1.3 2.1.1.45]
Organism
rcu  Ricinus communis (castor bean)
Pathway
Pyrimidine metabolism
One carbon pool by folate
Folate biosynthesis
Metabolic pathways
Module
Tetrahydrofolate biosynthesis, GTP => THF
Brite
KEGG Orthology (KO) [BR:rcu00001]
 Metabolism
  Nucleotide metabolism
   00240 Pyrimidine metabolism
    RCOM_1595270
  Metabolism of cofactors and vitamins
   00790 Folate biosynthesis
    RCOM_1595270
   00670 One carbon pool by folate
    RCOM_1595270
Enzymes [BR:rcu01000]
 1. Oxidoreductases
  1.5  Acting on the CH-NH group of donors
   1.5.1  With NAD+ or NADP+ as acceptor
    1.5.1.3  dihydrofolate reductase
     RCOM_1595270
 2. Transferases
  2.1  Transferring one-carbon groups
   2.1.1  Methyltransferases
    2.1.1.45  thymidylate synthase
     RCOM_1595270
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif Motif
Other DBs
NCBI-GI: 
NCBI-GeneID: 
UniProt: 
AA seq 591 aa AA seqDB search
MYGKIRLAFRRYLDFDAAMLTRVLLSSCKNSFWNSSYLSVAVTRLQIVSCESPKWRSYRR
LSVMSGDVSIGIPRGNANMHLDRNRRYQVVVAATRDMGIGKDGKLPWRLPSDLKFFKELT
LTTSSPGKRNAVVMGRKTWESIPLKYRPLPGRLNIVLTCSGGCDITTAEDVLTCGSIPSA
LELLAEAPYSFLIEKVFFIGGGQILRKTINAPGCDAIHITEIETSIECDTFIPVIDFSLF
HPWYSSLPIVENNVRYSFATYVRVKNSENGTLSKSASANGNLSSNTFEVKNFTFLPSIIY
KKHDEYMYLRLAEQIISNGTLKDDRTGTGTLSKFGGQMQYNLRKSFPLLTTKRVFWMGVV
EELLWFISGSTNAKVLQEKGIHIWDGNASRDYLDSIGLKDIEESDLGPIYGFQWRYFGAR
YTDMHADYSGQGFDQLVDVIDKIKSKPDDRCIILRSWNPSDLKLMAFPPCHMFAQFYVAN
GELSCQMYQRSADIGLGVPFNIAFYALLTCIIAHVCALVPGDFIHLIGDARVCTTHIGPL
QKQLQKLPTPFPILRINPAKKDIDSFEASDFQLIGYDPHEYIDMKNLSVDL
NT seq 1776 nt NT seq  +upstreamnt  +downstreamnt
atgtatggaaagatccggcttgctttcagaagatatctagattttgatgcagctatgctc
acccgagttttattgagttcttgtaagaatagcttctggaattcttcttatctatctgta
gcagtcacccgactacagatagtatcttgtgaatctccaaagtggagatcttacagaaga
ttatctgttatgagtggcgacgtttcaataggcattcctagaggcaatgccaatatgcat
cttgatcgaaataggagatatcaagttgtggttgctgctactcgtgatatggggattggg
aaggatgggaagttaccatggagattgccatctgatcttaagtttttcaaggagcttaca
ttgactacatcaagtcctggaaaaaggaatgcagttgtgatgggtaggaaaacatgggaa
agtattcccttgaagtacagacccctacctggacgcttgaatattgtgctgacttgttct
gggggttgtgatatcacaactgcagaagatgttttaacatgtggaagtattccatcagca
ttggagttattggcagaagcaccttacagttttttaattgagaaggttttttttatcggc
ggtggccagatattgaggaaaacaattaatgcaccaggatgtgatgctatccacatcact
gaaattgagacaagcattgaatgtgacaccttcattccagttattgatttttctttattt
cacccatggtattcctctctaccaatagtggaaaacaatgtccgatattcttttgcgaca
tatgttcgtgttaagaattcagaaaatggtactctttctaaaagcgcttcagcaaatggc
aatttaagttccaacacgtttgaagtaaagaattttacctttcttccaagtatcatttat
aagaaacatgatgaatatatgtatctaagactggctgaacaaattatctcaaatggcacc
ttgaaagatgacaggacaggcactggtaccctatcaaaatttggtggtcagatgcagtac
aatctgcgcaaatcttttccgcttcttacaacaaagagagtgttttggatgggagttgtt
gaagaacttttgtggtttattagtggttcaaccaatgcaaaggttctacaagagaaaggc
attcatatatgggacggtaatgcatccagagactaccttgacagtattggcctgaaagat
atagaagagagtgacctgggacccatatatggcttccagtggagatactttggcgctaga
tatacagatatgcatgctgactactctggccaaggatttgatcagctggtagacgttatt
gataagatcaagagtaaaccagatgacaggtgtattatcctcagatcatggaatccatca
gatcttaaattgatggcgtttccaccttgtcacatgtttgcacagttctatgtggctaat
ggggagctgtcttgtcaaatgtaccagcgatctgctgatatcggtcttggagtgccattt
aacattgccttttatgctttattgacatgcataattgcccatgtttgtgctcttgttcct
ggtgattttatccatttgattggggatgctcgtgtttgtacaactcatattgggcctttg
cagaagcagcttcagaaacttcctacacctttccctattctgaggataaatcctgcgaaa
aaggatattgattcatttgaggcatctgactttcaactcataggctatgatcctcatgag
tatatagatatgaaaaatctcagtgtagatctttaa

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