KEGG   REACTION: R00267Help
Entry
R00267                      Reaction                               
Name
Isocitrate:NADP+ oxidoreductase (decarboxylating)
Definition
Isocitrate + NADP+ <=> 2-Oxoglutarate + CO2 + NADPH + H+
Equation
Comment
two-step reaction (see R01899+R00268)
RPair
C00005_C00006 cofac
C00026_C00311 main
C00011_C00311 main
Enzyme
Pathway
Glutathione metabolism
Carbon fixation pathways in prokaryotes
Metabolic pathways
Microbial metabolism in diverse environments
2-Oxocarboxylic acid metabolism
Biosynthesis of amino acids
Orthology
K00031  
isocitrate dehydrogenase [EC:1.1.1.42]
KEGG   REACTION: R00268Help
Entry
R00268                      Reaction                               
Name
oxalosuccinate carboxy-lyase (2-oxoglutarate-forming)
Definition
Oxalosuccinate <=> 2-Oxoglutarate + CO2
Equation
Comment
the second step of two-step reaction (see R00267, R01899+R00268)
following after R01899
RPair
C00026_C05379 main
C00011_C05379 leave
Enzyme
Pathway
Citrate cycle (TCA cycle)
Metabolic pathways
Biosynthesis of secondary metabolites
Microbial metabolism in diverse environments
2-Oxocarboxylic acid metabolism
Orthology
K00031  
isocitrate dehydrogenase [EC:1.1.1.42]
KEGG   REACTION: R01899Help
Entry
R01899                      Reaction                               
Name
Isocitrate:NADP+ oxidoreductase
Definition
Isocitrate + NADP+ <=> Oxalosuccinate + NADPH + H+
Equation
Comment
the first step of two-step reaction (see R00267, R01899+R00268)
subsequently R00268
RPair
C00005_C00006 cofac
C00311_C05379 main
Enzyme
Pathway
Citrate cycle (TCA cycle)
Metabolic pathways
Biosynthesis of secondary metabolites
Microbial metabolism in diverse environments
2-Oxocarboxylic acid metabolism
Orthology
K00031  
isocitrate dehydrogenase [EC:1.1.1.42]
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