KEGG   REACTION: R00674Help
Entry
R00674                      Reaction                               

Name
L-serine hydro-lyase (adding indole; L-tryptophan-forming)
Definition
L-Serine + Indole <=> L-Tryptophan + H2O
Equation
Comment
multi-step reaction
intermediate (2-aminoacrylate Schiff base with PLP)
Reaction class
C00078_C00463
C00065_C00078
Enzyme
4.2.1.20        4.2.1.122
Pathway
Phenylalanine, tyrosine and tryptophan biosynthesis
Metabolic pathways
Biosynthesis of secondary metabolites
Orthology
K01695  
tryptophan synthase alpha chain [EC:4.2.1.20]
K01696  
tryptophan synthase beta chain [EC:4.2.1.20]
K06001  
tryptophan synthase beta chain [EC:4.2.1.20]

KEGG   REACTION: R02340Help
Entry
R02340                      Reaction                               

Name
(1S,2R)-1-C-(indol-3-yl)glycerol 3-phosphate D-glyceraldehyde-3-phosphate-lyase
Definition
Indoleglycerol phosphate <=> Indole + D-Glyceraldehyde 3-phosphate
Equation
Comment
a part of multi-step reaction (ec 4.2.1.20, see R02722, R02340+R00674)
Reaction class
C00118_C03506
C00463_C03506
Enzyme
4.1.2.8         4.2.1.20
Pathway
Phenylalanine, tyrosine and tryptophan biosynthesis
Benzoxazinoid biosynthesis
Metabolic pathways
Biosynthesis of secondary metabolites
Orthology
K01695  
tryptophan synthase alpha chain [EC:4.2.1.20]
K01696  
tryptophan synthase beta chain [EC:4.2.1.20]
K06001  
tryptophan synthase beta chain [EC:4.2.1.20]
K13222  
indole-3-glycerol-phosphate lyase [EC:4.1.2.8]

KEGG   REACTION: R02722Help
Entry
R02722                      Reaction                               

Name
L-serine hydro-lyase [adding 1-C-(indol-3-yl)glycerol 3-phosphate; L-tryptophan and glyceraldehyde-3-phosphate-forming]
Definition
L-Serine + Indoleglycerol phosphate <=> L-Tryptophan + D-Glyceraldehyde 3-phosphate + H2O
Equation
Comment
multi-step reaction (see R02340+R00674)
Reaction class
C00065_C00078
C00118_C03506
C00078_C03506
Enzyme
Pathway
Glycine, serine and threonine metabolism
Phenylalanine, tyrosine and tryptophan biosynthesis
Metabolic pathways
Biosynthesis of secondary metabolites
Biosynthesis of antibiotics
Biosynthesis of amino acids
Module
M00023  
Tryptophan biosynthesis, chorismate => tryptophan
Orthology
K01694  
tryptophan synthase [EC:4.2.1.20]
K01695  
tryptophan synthase alpha chain [EC:4.2.1.20]
K01696  
tryptophan synthase beta chain [EC:4.2.1.20]
K06001  
tryptophan synthase beta chain [EC:4.2.1.20]

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