KEGG   REACTION: R00674Help
Entry
R00674                      Reaction                               

Name
L-serine hydro-lyase (adding indole; L-tryptophan-forming)
Definition
L-Serine + Indole <=> L-Tryptophan + H2O
Equation
Comment
multi-step reaction
intermediate (2-aminoacrylate Schiff base with PLP)
RPair
C00078_C00463 main
C00065_C00078 main
C00001_C00065 leave
Enzyme
4.2.1.20        4.2.1.122
Pathway
Phenylalanine, tyrosine and tryptophan biosynthesis
Metabolic pathways
Biosynthesis of secondary metabolites
Orthology
K01695  
tryptophan synthase alpha chain [EC:4.2.1.20]
K01696  
tryptophan synthase beta chain [EC:4.2.1.20]
K06001  
tryptophan synthase beta chain [EC:4.2.1.20]

KEGG   REACTION: R02340Help
Entry
R02340                      Reaction                               

Name
(1S,2R)-1-C-(indol-3-yl)glycerol 3-phosphate D-glyceraldehyde-3-phosphate-lyase
Definition
Indoleglycerol phosphate <=> Indole + D-Glyceraldehyde 3-phosphate
Equation
Comment
a part of multi-step reaction (ec 4.2.1.20, see R02722, R02340+R00674)
RPair
C00118_C03506 main
C00463_C03506 main
Enzyme
4.1.2.8         4.2.1.20
Pathway
Phenylalanine, tyrosine and tryptophan biosynthesis
Benzoxazinoid biosynthesis
Metabolic pathways
Biosynthesis of secondary metabolites
Orthology
K01695  
tryptophan synthase alpha chain [EC:4.2.1.20]
K01696  
tryptophan synthase beta chain [EC:4.2.1.20]
K06001  
tryptophan synthase beta chain [EC:4.2.1.20]
K13222  
indole-3-glycerol-phosphate lyase [EC:4.1.2.8]

KEGG   REACTION: R02722Help
Entry
R02722                      Reaction                               

Name
L-serine hydro-lyase [adding 1-C-(indol-3-yl)glycerol 3-phosphate; L-tryptophan and glyceraldehyde-3-phosphate-forming]
Definition
L-Serine + Indoleglycerol phosphate <=> L-Tryptophan + D-Glyceraldehyde 3-phosphate + H2O
Equation
Comment
multi-step reaction (see R02340+R00674)
RPair
C00065_C00078 main
C00118_C03506 main
C00001_C00065 leave
C00078_C03506 main
Enzyme
Pathway
Glycine, serine and threonine metabolism
Phenylalanine, tyrosine and tryptophan biosynthesis
Metabolic pathways
Biosynthesis of secondary metabolites
Biosynthesis of amino acids
Orthology
K01694  
tryptophan synthase [EC:4.2.1.20]
K01695  
tryptophan synthase alpha chain [EC:4.2.1.20]
K01696  
tryptophan synthase beta chain [EC:4.2.1.20]
K06001  
tryptophan synthase beta chain [EC:4.2.1.20]

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