KEGG   REACTION: R01088
Entry
R01088                      Reaction                               
Name
L-leucine:NAD+ oxidoreductase (deaminating)
Definition
L-Leucine + H2O + NAD+ <=> 4-Methyl-2-oxopentanoate + Ammonia + NADH + H+
Equation
C00123 + C00001 + C00003 <=> C00233 + C00014 + C00004 + C00080
Reaction class
RC00001  C00003_C00004
RC00006  C00123_C00233
Enzyme
1.4.1.9
Pathway
rn00280  Valine, leucine and isoleucine degradation
rn00290  Valine, leucine and isoleucine biosynthesis
rn01100  Metabolic pathways
rn01110  Biosynthesis of secondary metabolites
Brite
Enzymatic reactions [BR:br08201]
 1. Oxidoreductase reactions
  1.4  Acting on the CH-NH2 group of donors
   1.4.1  With NAD+ or NADP+ as acceptor
    1.4.1.9
     R01088  L-Leucine + H2O + NAD+ <=> 4-Methyl-2-oxopentanoate + Ammonia + NADH + H+
Orthology
K00263  leucine dehydrogenase [EC:1.4.1.9]
Other DBs
RHEA: 12223

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Ontology (1)   
   KEGG BRITE (1)   
Pathway (8)   
   KEGG PATHWAY (8)   
Chemical substance (7)   
   KEGG COMPOUND (7)   
Chemical reaction (4)   
   KEGG ENZYME (1)   
   KEGG RCLASS (2)   
   SABIO-RK (1)   
Gene (2099)   
   KEGG ORTHOLOGY (1)   
   KEGG GENES (2098)   
All databases (2119)   

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KEGG   REACTION: R00145
Entry
R00145                      Reaction                               
Name
alpha-amino acid:NAD+ oxidoreductase (deaminating)
Definition
alpha-Amino acid + H2O + NAD+ <=> 2-Oxo acid + Ammonia + NADH + H+
Equation
C05167 + C00001 + C00003 <=> C00161 + C00014 + C00004 + C00080
Comment
general reaction, NADPH(see R00146)
Reaction class
RC00001  C00003_C00004
RC00025  C00161_C05167
Enzyme
1.4.1.1         1.4.1.2         1.4.1.3         1.4.1.4         
1.4.1.5         1.4.1.7         1.4.1.8         1.4.1.9         
1.4.1.10        1.4.1.12        1.4.1.15        1.4.1.19        
1.4.1.20
Brite
Enzymatic reactions [BR:br08201]
 1. Oxidoreductase reactions
  1.4  Acting on the CH-NH2 group of donors
   1.4.1  With NAD+ or NADP+ as acceptor
    1.4.1.1
     R00145  alpha-Amino acid + H2O + NAD+ <=> 2-Oxo acid + Ammonia + NADH + H+
    1.4.1.2
     R00145  alpha-Amino acid + H2O + NAD+ <=> 2-Oxo acid + Ammonia + NADH + H+
    1.4.1.3
     R00145  alpha-Amino acid + H2O + NAD+ <=> 2-Oxo acid + Ammonia + NADH + H+
    1.4.1.4
     R00145  alpha-Amino acid + H2O + NAD+ <=> 2-Oxo acid + Ammonia + NADH + H+
    1.4.1.5
     R00145  alpha-Amino acid + H2O + NAD+ <=> 2-Oxo acid + Ammonia + NADH + H+
    1.4.1.7
     R00145  alpha-Amino acid + H2O + NAD+ <=> 2-Oxo acid + Ammonia + NADH + H+
    1.4.1.8
     R00145  alpha-Amino acid + H2O + NAD+ <=> 2-Oxo acid + Ammonia + NADH + H+
    1.4.1.9
     R00145  alpha-Amino acid + H2O + NAD+ <=> 2-Oxo acid + Ammonia + NADH + H+
    1.4.1.10
     R00145  alpha-Amino acid + H2O + NAD+ <=> 2-Oxo acid + Ammonia + NADH + H+
    1.4.1.12
     R00145  alpha-Amino acid + H2O + NAD+ <=> 2-Oxo acid + Ammonia + NADH + H+
    1.4.1.15
     R00145  alpha-Amino acid + H2O + NAD+ <=> 2-Oxo acid + Ammonia + NADH + H+
    1.4.1.19
     R00145  alpha-Amino acid + H2O + NAD+ <=> 2-Oxo acid + Ammonia + NADH + H+
    1.4.1.20
     R00145  alpha-Amino acid + H2O + NAD+ <=> 2-Oxo acid + Ammonia + NADH + H+

  All links  
Ontology (1)   
   KEGG BRITE (1)   
Chemical substance (7)   
   KEGG COMPOUND (7)   
Chemical reaction (15)   
   KEGG ENZYME (13)   
   KEGG RCLASS (2)   
All databases (23)   

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KEGG   REACTION: R00146
Entry
R00146                      Reaction                               
Name
alpha-amino acid:NADP+ oxidoreductase (deaminating)
Definition
alpha-Amino acid + H2O + NADP+ <=> 2-Oxo acid + Ammonia + NADPH + H+
Equation
C05167 + C00001 + C00006 <=> C00161 + C00014 + C00005 + C00080
Comment
general reaction, NADH(see R00145)
Reaction class
RC00001  C00005_C00006
RC00025  C00161_C05167
Enzyme
1.4.1.1         1.4.1.2         1.4.1.3         1.4.1.4         
1.4.1.5         1.4.1.7         1.4.1.8         1.4.1.9         
1.4.1.10        1.4.1.12        1.4.1.15        1.4.1.19        
1.4.1.20
Brite
Enzymatic reactions [BR:br08201]
 1. Oxidoreductase reactions
  1.4  Acting on the CH-NH2 group of donors
   1.4.1  With NAD+ or NADP+ as acceptor
    1.4.1.1
     R00146  alpha-Amino acid + H2O + NADP+ <=> 2-Oxo acid + Ammonia + NADPH + H+
    1.4.1.2
     R00146  alpha-Amino acid + H2O + NADP+ <=> 2-Oxo acid + Ammonia + NADPH + H+
    1.4.1.3
     R00146  alpha-Amino acid + H2O + NADP+ <=> 2-Oxo acid + Ammonia + NADPH + H+
    1.4.1.4
     R00146  alpha-Amino acid + H2O + NADP+ <=> 2-Oxo acid + Ammonia + NADPH + H+
    1.4.1.5
     R00146  alpha-Amino acid + H2O + NADP+ <=> 2-Oxo acid + Ammonia + NADPH + H+
    1.4.1.7
     R00146  alpha-Amino acid + H2O + NADP+ <=> 2-Oxo acid + Ammonia + NADPH + H+
    1.4.1.8
     R00146  alpha-Amino acid + H2O + NADP+ <=> 2-Oxo acid + Ammonia + NADPH + H+
    1.4.1.9
     R00146  alpha-Amino acid + H2O + NADP+ <=> 2-Oxo acid + Ammonia + NADPH + H+
    1.4.1.10
     R00146  alpha-Amino acid + H2O + NADP+ <=> 2-Oxo acid + Ammonia + NADPH + H+
    1.4.1.12
     R00146  alpha-Amino acid + H2O + NADP+ <=> 2-Oxo acid + Ammonia + NADPH + H+
    1.4.1.15
     R00146  alpha-Amino acid + H2O + NADP+ <=> 2-Oxo acid + Ammonia + NADPH + H+
    1.4.1.19
     R00146  alpha-Amino acid + H2O + NADP+ <=> 2-Oxo acid + Ammonia + NADPH + H+
    1.4.1.20
     R00146  alpha-Amino acid + H2O + NADP+ <=> 2-Oxo acid + Ammonia + NADPH + H+

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Ontology (1)   
   KEGG BRITE (1)   
Chemical substance (7)   
   KEGG COMPOUND (7)   
Chemical reaction (15)   
   KEGG ENZYME (13)   
   KEGG RCLASS (2)   
All databases (23)   

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KEGG   REACTION: R01434
Entry
R01434                      Reaction                               
Name
L-valine:NAD+ oxidoreductase(deaminating)
Definition
L-Valine + H2O + NAD+ <=> 3-Methyl-2-oxobutanoic acid + Ammonia + NADH + H+
Equation
C00183 + C00001 + C00003 <=> C00141 + C00014 + C00004 + C00080
Reaction class
RC00001  C00003_C00004
RC00036  C00141_C00183
Enzyme
1.4.1.9         1.4.1.23
Pathway
rn00280  Valine, leucine and isoleucine degradation
rn00290  Valine, leucine and isoleucine biosynthesis
rn01100  Metabolic pathways
rn01110  Biosynthesis of secondary metabolites
Brite
Enzymatic reactions [BR:br08201]
 1. Oxidoreductase reactions
  1.4  Acting on the CH-NH2 group of donors
   1.4.1  With NAD+ or NADP+ as acceptor
    1.4.1.9
     R01434  L-Valine + H2O + NAD+ <=> 3-Methyl-2-oxobutanoic acid + Ammonia + NADH + H+
    1.4.1.23
     R01434  L-Valine + H2O + NAD+ <=> 3-Methyl-2-oxobutanoic acid + Ammonia + NADH + H+
Orthology
K00263  leucine dehydrogenase [EC:1.4.1.9]
K00271  valine dehydrogenase (NAD+) [EC:1.4.1.23]
Other DBs
RHEA: 30766

  All links  
Ontology (1)   
   KEGG BRITE (1)   
Pathway (8)   
   KEGG PATHWAY (8)   
Chemical substance (7)   
   KEGG COMPOUND (7)   
Chemical reaction (5)   
   KEGG ENZYME (2)   
   KEGG RCLASS (2)   
   SABIO-RK (1)   
Gene (2483)   
   KEGG ORTHOLOGY (2)   
   KEGG GENES (2481)   
All databases (2504)   

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KEGG   REACTION: R02196
Entry
R02196                      Reaction                               
Name
L-isoleucine:NAD+ oxidoreductase(deaminating)
Definition
L-Isoleucine + NAD+ + H2O <=> (S)-3-Methyl-2-oxopentanoic acid + Ammonia + NADH + H+
Equation
C00407 + C00003 + C00001 <=> C00671 + C00014 + C00004 + C00080
Reaction class
RC00001  C00003_C00004
RC00036  C00407_C00671
Enzyme
1.4.1.9
Pathway
rn00290  Valine, leucine and isoleucine biosynthesis
rn01100  Metabolic pathways
rn01110  Biosynthesis of secondary metabolites
Brite
Enzymatic reactions [BR:br08201]
 1. Oxidoreductase reactions
  1.4  Acting on the CH-NH2 group of donors
   1.4.1  With NAD+ or NADP+ as acceptor
    1.4.1.9
     R02196  L-Isoleucine + NAD+ + H2O <=> (S)-3-Methyl-2-oxopentanoic acid + Ammonia + NADH + H+
Orthology
K00263  leucine dehydrogenase [EC:1.4.1.9]
Other DBs
RHEA: 32962

  All links  
Ontology (1)   
   KEGG BRITE (1)   
Pathway (6)   
   KEGG PATHWAY (6)   
Chemical substance (7)   
   KEGG COMPOUND (7)   
Chemical reaction (3)   
   KEGG ENZYME (1)   
   KEGG RCLASS (2)   
Gene (2099)   
   KEGG ORTHOLOGY (1)   
   KEGG GENES (2098)   
All databases (2116)   

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