KEGG   REACTION: R01158Help
Entry
R01158                      Reaction                               

Name
L-histidinol:NAD+ oxidoreductase
Definition
L-Histidinol + 2 NAD+ + H2O <=> L-Histidine + 2 NADH + 2 H+
Equation
C00860 + 2 C00003 + C00001 <=> C00135 + 2 C00004 + 2 C00080
Comment
two-step reaction (see R03012+R01163)
RPair
C00003_C00004 cofac [RC:RC00001]
C00135_C00860 main [RC:RC00463]
C00001_C00135 leave
Enzyme
Pathway
Biosynthesis of amino acids
Orthology
K00013  
histidinol dehydrogenase [EC:1.1.1.23]
K14152  
phosphoribosyl-ATP pyrophosphohydrolase / phosphoribosyl-AMP cyclohydrolase / histidinol dehydrogenase [EC:3.6.1.31 3.5.4.19 1.1.1.23]

KEGG   REACTION: R01163Help
Entry
R01163                      Reaction                               

Name
L-histidinal:NAD+ oxidoreductase
Definition
L-Histidinal + H2O + NAD+ <=> L-Histidine + NADH + H+
Equation
Comment
second step of two-step reaction (R01158, R03012+R01163)
following after R03012
RPair
C00003_C00004 cofac [RC:RC00001]
C00135_C01929 main [RC:RC00242]
C00001_C00135 leave
Enzyme
Pathway
Histidine metabolism
Metabolic pathways
Biosynthesis of secondary metabolites
Module
M00026  
Histidine biosynthesis, PRPP => histidine
Orthology
K00013  
histidinol dehydrogenase [EC:1.1.1.23]
K14152  
phosphoribosyl-ATP pyrophosphohydrolase / phosphoribosyl-AMP cyclohydrolase / histidinol dehydrogenase [EC:3.6.1.31 3.5.4.19 1.1.1.23]

KEGG   REACTION: R03012Help
Entry
R03012                      Reaction                               

Name
L-Histidinol:NAD+ oxidoreductase
Definition
L-Histidinol + NAD+ <=> L-Histidinal + NADH + H+
Equation
Comment
first step of two-step reaction (R01158, R03012+R01163)
subsequently R01163
RPair
C00003_C00004 cofac [RC:RC00001]
C00860_C01929 main [RC:RC00099]
Enzyme
Pathway
Histidine metabolism
Metabolic pathways
Biosynthesis of secondary metabolites
Module
M00026  
Histidine biosynthesis, PRPP => histidine
Orthology
K00013  
histidinol dehydrogenase [EC:1.1.1.23]
K14152  
phosphoribosyl-ATP pyrophosphohydrolase / phosphoribosyl-AMP cyclohydrolase / histidinol dehydrogenase [EC:3.6.1.31 3.5.4.19 1.1.1.23]

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