KEGG   REACTION: R02570Help
Entry
R02570                      Reaction                               

Name
succinyl-CoA:enzyme N6-(dihydrolipoyl)lysine S-succinyltransferase
Definition
Succinyl-CoA + Enzyme N6-(dihydrolipoyl)lysine <=> CoA + [Dihydrolipoyllysine-residue succinyltransferase] S-succinyldihydrolipoyllysine
Equation
Comment
2-oxoglutarate dehydrogenase complex:dihydrolipoyllysine-residue succinyltransferase
a part of multi-step reaction (see R08549, R01700+R02570+R07618)
following after R01700
RPair
C00010_C00091 main [RC:RC00004]
C00091_C16254 main [RC:RC02727]
C15973_C16254 main [RC:RC00004]
Enzyme
Pathway
Citrate cycle (TCA cycle)
Metabolic pathways
Biosynthesis of secondary metabolites
Microbial metabolism in diverse environments
Module
M00009  
Citrate cycle (TCA cycle, Krebs cycle)
M00011  
Citrate cycle, second carbon oxidation, 2-oxoglutarate => oxaloacetate
Orthology
K00658  
2-oxoglutarate dehydrogenase E2 component (dihydrolipoamide succinyltransferase) [EC:2.3.1.61]

KEGG   REACTION: R01933Help
Entry
R01933                      Reaction                               

Name
2-oxoadipate dehydrogenase complex
Definition
2-Oxoadipate + CoA + NAD+ <=> Glutaryl-CoA + CO2 + NADH + H+
Equation
Comment
2-oxoglutarate dehydrogenase complex (see R08549)
multi-step reaction (see R01940+R02571+R07618)
RPair
C00003_C00004 cofac [RC:RC00001]
C00010_C00527 main [RC:RC00004]
C00322_C00527 main [RC:RC02833]
C00011_C00322 leave
Enzyme
1.2.4.2         1.8.1.4         2.3.1.61
Pathway
Tryptophan metabolism
Orthology
K00164  
2-oxoglutarate dehydrogenase E1 component [EC:1.2.4.2]

KEGG   REACTION: R02571Help
Entry
R02571                      Reaction                               

Name
Glutaryl-CoA:dihydrolipoamide S-succinyltransferase
Definition
Glutaryl-CoA + Enzyme N6-(dihydrolipoyl)lysine <=> CoA + [Dihydrolipoyllysine-residue succinyltransferase] S-glutaryldihydrolipoyllysine
Equation
Comment
2-oxoglutarate dehydrogenase complex:dihydrolipoyllysine-residue succinyltransferase
a part of multi-step reaction (see R01933, R01940+R02571+R07618)
following after R01940
RPair
C00010_C00527 main [RC:RC00004]
C06157_C15973 main [RC:RC00004]
C00527_C06157 main [RC:RC02727]
Enzyme
Pathway
Lysine degradation
Metabolic pathways
Module
M00032  
Lysine degradation, lysine => saccharopine => acetoacetyl-CoA
Orthology
K00658  
2-oxoglutarate dehydrogenase E2 component (dihydrolipoamide succinyltransferase) [EC:2.3.1.61]

KEGG   REACTION: R08549Help
Entry
R08549                      Reaction                               

Name
2-Oxoglutarate dehydrogenase complex
Definition
2-Oxoglutarate + CoA + NAD+ <=> Succinyl-CoA + CO2 + NADH + H+
Equation
Comment
multi-step reaction (see R01700+R02570+R07618)
RPair
C00003_C00004 cofac [RC:RC00001]
C00010_C00091 main [RC:RC00004]
C00026_C00091 main [RC:RC02833]
C00011_C00026 leave
Enzyme
1.2.4.2         1.8.1.4         2.3.1.61
Pathway
Metabolic pathways
Biosynthesis of secondary metabolites
Carbon metabolism
Orthology
K00164  
2-oxoglutarate dehydrogenase E1 component [EC:1.2.4.2]
K00382  
dihydrolipoamide dehydrogenase [EC:1.8.1.4]
K00658  
2-oxoglutarate dehydrogenase E2 component (dihydrolipoamide succinyltransferase) [EC:2.3.1.61]

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