KEGG   REACTION: R04590
Entry
R04590                      Reaction                               
Name
CMP-N-acetylneuraminate:beta-D-galactoside alpha-2,3-N-acetylneuraminyltransferase
Definition
CMP-N-acetylneuraminate + beta-D-Galactosyl-1,3-N-acetyl-alpha-D-galactosaminyl-R <=> CMP + alpha-N-Acetylneuraminyl-2,3-beta-D-galactosyl-1,3-N-acetyl-alpha-D-galactosaminyl-R
Equation
C00128 + C04750 <=> C00055 + C04901
Remark
Same as: R05913
Reaction class
RC00009  C00055_C00128
RC00077  C04750_C04901
Enzyme
2.4.3.4
Brite
Enzymatic reactions [BR:br08201]
 2. Transferase reactions
  2.4  Glycosyltransferases
   2.4.3  Sialyltransferases
    2.4.3.4
     R04590  CMP-N-acetylneuraminate + beta-D-Galactosyl-1,3-N-acetyl-alpha-D-galactosaminyl-R <=> CMP + alpha-N-Acetylneuraminyl-2,3-beta-D-galactosyl-1,3-N-acetyl-alpha-D-galactosaminyl-R
Other DBs
RHEA: 21619

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Ontology (1)   
   KEGG BRITE (1)   
Chemical substance (4)   
   KEGG COMPOUND (4)   
Chemical reaction (3)   
   KEGG ENZYME (1)   
   KEGG RCLASS (2)   
All databases (8)   

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KEGG   REACTION: R05913
Entry
R05913                      Reaction                               
Definition
CMP-N-acetylneuraminate + Thomsen-Friedenreich antigen <=> CMP + Sialyl T antigen
Equation
G10616 + G00024 <=> G10621 + G00026
Remark
Same as: R04590
Enzyme
2.4.3.4
Pathway
rn00512  Mucin type O-glycan biosynthesis
rn01100  Metabolic pathways
Brite
Enzymatic reactions [BR:br08201]
 2. Transferase reactions
  2.4  Glycosyltransferases
   2.4.3  Sialyltransferases
    2.4.3.4
     R05913  CMP-N-acetylneuraminate + Thomsen-Friedenreich antigen <=> CMP + Sialyl T antigen
Glycosyltransferase reactions [BR:br08203]
 Sialyltransferase reactions
  R05913  Neu5Ac a2-3 Gal
Orthology
K00780  beta-galactoside alpha-2,3-sialyltransferase (sialyltransferase 4A) [EC:2.4.3.2 2.4.3.4]
K03368  beta-galactoside alpha-2,3-sialyltransferase (sialyltransferase 4B) [EC:2.4.3.2 2.4.3.4]
Other DBs
RHEA: 56207 56211

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Ontology (2)   
   KEGG BRITE (2)   
Pathway (4)   
   KEGG PATHWAY (4)   
Chemical substance (4)   
   KEGG GLYCAN (4)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Gene (825)   
   KEGG ORTHOLOGY (2)   
   KEGG GENES (823)   
All databases (836)   

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KEGG   REACTION: R04648
Entry
R04648                      Reaction                               
Name
CMP-N-acetylneuraminate:D-galactosyl-N-acetyl-D-galactosaminyl-(N-acetylneuraminyl)-D-galactosyl-D-glucosylceramide N-acetylneuraminyltransferase
Definition
CMP-N-acetylneuraminate + D-Galactosyl-N-acetyl-D-galactosaminyl-(N-acetylneuraminyl)-D-galactosyl-D-glucosylceramide <=> CMP + N-Acetylneuraminyl-D-galactosyl-N-acetyl-D-galactosaminyl-(N-acetylneuraminyl)-D-galactosyl-D-glucosylceramide
Equation
C00128 + C04911 <=> C00055 + C04927
Remark
Same as: R05942
Reaction class
RC00009  C00055_C00128
RC00077  C04911_C04927
Enzyme
2.4.3.2
Brite
Enzymatic reactions [BR:br08201]
 2. Transferase reactions
  2.4  Glycosyltransferases
   2.4.3  Sialyltransferases
    2.4.3.2
     R04648  CMP-N-acetylneuraminate + D-Galactosyl-N-acetyl-D-galactosaminyl-(N-acetylneuraminyl)-D-galactosyl-D-glucosylceramide <=> CMP + N-Acetylneuraminyl-D-galactosyl-N-acetyl-D-galactosaminyl-(N-acetylneuraminyl)-D-galactosyl-D-glucosylceramide
Other DBs
RHEA: 18024

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Ontology (1)   
   KEGG BRITE (1)   
Chemical substance (4)   
   KEGG COMPOUND (4)   
Chemical reaction (3)   
   KEGG ENZYME (1)   
   KEGG RCLASS (2)   
All databases (8)   

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KEGG   REACTION: R05116
Entry
R05116                      Reaction                               
Definition
CMP-N-acetylneuraminate + GD1b <=> CMP + GT1b
Equation
C00128 + C06141 <=> C00055 + C06140
Remark
Same as: R05949
Reaction class
RC00009  C00055_C00128
RC00077  C06140_C06141
Enzyme
2.4.3.2
Brite
Enzymatic reactions [BR:br08201]
 2. Transferase reactions
  2.4  Glycosyltransferases
   2.4.3  Sialyltransferases
    2.4.3.2
     R05116  CMP-N-acetylneuraminate + GD1b <=> CMP + GT1b

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Ontology (1)   
   KEGG BRITE (1)   
Chemical substance (4)   
   KEGG COMPOUND (4)   
Chemical reaction (3)   
   KEGG ENZYME (1)   
   KEGG RCLASS (2)   
All databases (8)   

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KEGG   REACTION: R05942
Entry
R05942                      Reaction                               
Definition
CMP-N-acetylneuraminate + GM1 <=> CMP + GD1a
Equation
G10616 + G00110 <=> G10621 + G00111
Remark
Same as: R04648
Enzyme
2.4.3.2
Pathway
rn00604  Glycosphingolipid biosynthesis - ganglio series
rn01100  Metabolic pathways
Brite
Enzymatic reactions [BR:br08201]
 2. Transferase reactions
  2.4  Glycosyltransferases
   2.4.3  Sialyltransferases
    2.4.3.2
     R05942  CMP-N-acetylneuraminate + GM1 <=> CMP + GD1a
Glycosyltransferase reactions [BR:br08203]
 Sialyltransferase reactions
  R05942  Neu5Ac a2-3 Gal
Orthology
K00780  beta-galactoside alpha-2,3-sialyltransferase (sialyltransferase 4A) [EC:2.4.3.2 2.4.3.4]
K03368  beta-galactoside alpha-2,3-sialyltransferase (sialyltransferase 4B) [EC:2.4.3.2 2.4.3.4]

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Ontology (2)   
   KEGG BRITE (2)   
Pathway (4)   
   KEGG PATHWAY (4)   
Chemical substance (4)   
   KEGG GLYCAN (4)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Gene (825)   
   KEGG ORTHOLOGY (2)   
   KEGG GENES (823)   
All databases (836)   

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KEGG   REACTION: R05949
Entry
R05949                      Reaction                               
Definition
CMP-N-acetylneuraminate + GD1b <=> CMP + GT1b
Equation
G10616 + G00115 <=> G10621 + G00116
Remark
Same as: R05116
Enzyme
2.4.3.2
Pathway
rn00604  Glycosphingolipid biosynthesis - ganglio series
rn01100  Metabolic pathways
Brite
Enzymatic reactions [BR:br08201]
 2. Transferase reactions
  2.4  Glycosyltransferases
   2.4.3  Sialyltransferases
    2.4.3.2
     R05949  CMP-N-acetylneuraminate + GD1b <=> CMP + GT1b
Glycosyltransferase reactions [BR:br08203]
 Sialyltransferase reactions
  R05949  Neu5Ac a2-3 Gal
Orthology
K00780  beta-galactoside alpha-2,3-sialyltransferase (sialyltransferase 4A) [EC:2.4.3.2 2.4.3.4]
K03368  beta-galactoside alpha-2,3-sialyltransferase (sialyltransferase 4B) [EC:2.4.3.2 2.4.3.4]

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Ontology (2)   
   KEGG BRITE (2)   
Pathway (4)   
   KEGG PATHWAY (4)   
Chemical substance (4)   
   KEGG GLYCAN (4)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Gene (825)   
   KEGG ORTHOLOGY (2)   
   KEGG GENES (823)   
All databases (836)   

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KEGG   REACTION: R05957
Entry
R05957                      Reaction                               
Definition
CMP-N-acetylneuraminate + Asialo-GM1 <=> CMP + GM1b
Equation
G10616 + G00124 <=> G10621 + G00125
Enzyme
2.4.3.2
Pathway
rn00604  Glycosphingolipid biosynthesis - ganglio series
rn01100  Metabolic pathways
Brite
Enzymatic reactions [BR:br08201]
 2. Transferase reactions
  2.4  Glycosyltransferases
   2.4.3  Sialyltransferases
    2.4.3.2
     R05957  CMP-N-acetylneuraminate + Asialo-GM1 <=> CMP + GM1b
IUBMB reaction hierarchy [BR:br08202]
 2. Transferase reactions
  2.4.3.2
   R11715  beta-D-Galactosyl-(1->3)-N-acetyl-beta-D-galactosaminyl-R <=> N-Acetyl-alpha-neuraminyl-(2->3)-beta-D-galactosyl-(1->3)-N-acetyl-beta-D-galactosaminyl-R
    R05957  Asialo-GM1 <=> GM1b
Glycosyltransferase reactions [BR:br08203]
 Sialyltransferase reactions
  R05957  Neu5Ac a2-3 Gal
Orthology
K00780  beta-galactoside alpha-2,3-sialyltransferase (sialyltransferase 4A) [EC:2.4.3.2 2.4.3.4]
K03368  beta-galactoside alpha-2,3-sialyltransferase (sialyltransferase 4B) [EC:2.4.3.2 2.4.3.4]

  All links  
Ontology (3)   
   KEGG BRITE (3)   
Pathway (4)   
   KEGG PATHWAY (4)   
Chemical substance (4)   
   KEGG GLYCAN (4)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Gene (825)   
   KEGG ORTHOLOGY (2)   
   KEGG GENES (823)   
All databases (837)   

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KEGG   REACTION: R05967
Entry
R05967                      Reaction                               
Definition
CMP-N-acetylneuraminate + Galactosylgloboside <=> CMP + Monosialylgalactosylgloboside
Equation
G10616 + G00097 <=> G10621 + G00098
Enzyme
2.4.3.2
Pathway
rn00603  Glycosphingolipid biosynthesis - globo and isoglobo series
rn01100  Metabolic pathways
Brite
Enzymatic reactions [BR:br08201]
 2. Transferase reactions
  2.4  Glycosyltransferases
   2.4.3  Sialyltransferases
    2.4.3.2
     R05967  CMP-N-acetylneuraminate + Galactosylgloboside <=> CMP + Monosialylgalactosylgloboside
IUBMB reaction hierarchy [BR:br08202]
 2. Transferase reactions
  2.4.3.2
   R11715  beta-D-Galactosyl-(1->3)-N-acetyl-beta-D-galactosaminyl-R <=> N-Acetyl-alpha-neuraminyl-(2->3)-beta-D-galactosyl-(1->3)-N-acetyl-beta-D-galactosaminyl-R
    R05967  Galactosylgloboside <=> Monosialylgalactosylgloboside
Glycosyltransferase reactions [BR:br08203]
 Sialyltransferase reactions
  R05967  Neu5Ac a2-3 Gal
Orthology
K00780  beta-galactoside alpha-2,3-sialyltransferase (sialyltransferase 4A) [EC:2.4.3.2 2.4.3.4]
K03368  beta-galactoside alpha-2,3-sialyltransferase (sialyltransferase 4B) [EC:2.4.3.2 2.4.3.4]

  All links  
Ontology (3)   
   KEGG BRITE (3)   
Pathway (4)   
   KEGG PATHWAY (4)   
Chemical substance (4)   
   KEGG GLYCAN (4)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Gene (825)   
   KEGG ORTHOLOGY (2)   
   KEGG GENES (823)   
All databases (837)   

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