KEGG   REACTION: R07374
Entry
R07374                      Reaction                               
Name
(25R)-3alpha,7alpha,12alpha-trihydroxy-5beta-cholestan-26-oyl-CoA:acceptor 24-oxidoreductase (24R-hydroxylating)
Definition
(25R)-3alpha,7alpha,12alpha-Trihydroxy-5beta-cholestan-26-oyl-CoA + H2O + Acceptor <=> (24R,25R)-3alpha,7alpha,12alpha,24-Tetrahydroxy-5beta-cholestanoyl-CoA + Reduced acceptor
Equation
Reaction class
RC00773  C15613_C15614
Enzyme
Brite
Enzymatic reactions [BR:br08201]
 1. Oxidoreductase reactions
  1.17  Acting on CH or CH2 groups
   1.17.99  With unknown physiological acceptors
    1.17.99.3
     R07374  (25R)-3alpha,7alpha,12alpha-Trihydroxy-5beta-cholestan-26-oyl-CoA + H2O + Acceptor <=> (24R,25R)-3alpha,7alpha,12alpha,24-Tetrahydroxy-5beta-cholestanoyl-CoA + Reduced acceptor
Other DBs
RHEA: 15736

KEGG   REACTION: R08735
Entry
R08735                      Reaction                               
Name
(25S)-3alpha,7alpha,12alpha-trihydroxy-5beta-cholestan-26-oyl-CoA:acceptor 24,25-oxidoreductase
Definition
(25S)-3alpha,7alpha,12alpha-Trihydroxy-5beta-cholestan-26-oyl-CoA + Acceptor <=> (24E)-3alpha,7alpha,12alpha-Trihydroxy-5beta-cholest-24-enoyl-CoA + Reduced acceptor
Equation
Comment
branched-chain acyl-CoA oxidase uses oxygen [CPD:C00007] as the acceptor (similar to ec 1.3.3.6, R00388)
Reaction class
RC01942  C05460_C17343
Enzyme
Pathway
rn00120  Primary bile acid biosynthesis
rn01100  Metabolic pathways
Module
M00104  Bile acid biosynthesis, cholesterol => cholate/chenodeoxycholate
M00862  beta-Oxidation, peroxisome, tri/dihydroxycholestanoyl-CoA => choloyl/chenodeoxycholoyl-CoA
Brite
Enzymatic reactions [BR:br08201]
 1. Oxidoreductase reactions
  1.17  Acting on CH or CH2 groups
   1.17.99  With unknown physiological acceptors
    1.17.99.3
     R08735  (25S)-3alpha,7alpha,12alpha-Trihydroxy-5beta-cholestan-26-oyl-CoA + Acceptor <=> (24E)-3alpha,7alpha,12alpha-Trihydroxy-5beta-cholest-24-enoyl-CoA + Reduced acceptor
Orthology
K10214  3alpha,7alpha,12alpha-trihydroxy-5beta-cholestanoyl-CoA 24-hydroxylase [EC:1.17.99.3]

KEGG   REACTION: R08740
Entry
R08740                      Reaction                               
Name
(25S)-3alpha,7alpha-dihydroxy-5beta-cholestanoyl-CoA:acceptor 24,25-oxidoreductase
Definition
(25S)-3alpha,7alpha-Dihydroxy-5beta-cholestanoyl-CoA + Acceptor <=> (24E)-3alpha,7alpha-Dihydroxy-5beta-cholest-24-enoyl-CoA + Reduced acceptor
Equation
Comment
branched-chain acyl-CoA oxidase uses oxygen [CPD:C00007] as the acceptor (similar to ec 1.3.3.6, R00388)
Reaction class
RC01942  C05447_C17346
Enzyme
Pathway
rn00120  Primary bile acid biosynthesis
rn01100  Metabolic pathways
Module
M00104  Bile acid biosynthesis, cholesterol => cholate/chenodeoxycholate
M00862  beta-Oxidation, peroxisome, tri/dihydroxycholestanoyl-CoA => choloyl/chenodeoxycholoyl-CoA
Brite
Enzymatic reactions [BR:br08201]
 1. Oxidoreductase reactions
  1.17  Acting on CH or CH2 groups
   1.17.99  With unknown physiological acceptors
    1.17.99.3
     R08740  (25S)-3alpha,7alpha-Dihydroxy-5beta-cholestanoyl-CoA + Acceptor <=> (24E)-3alpha,7alpha-Dihydroxy-5beta-cholest-24-enoyl-CoA + Reduced acceptor
Orthology
K10214  3alpha,7alpha,12alpha-trihydroxy-5beta-cholestanoyl-CoA 24-hydroxylase [EC:1.17.99.3]

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