GenomeNet

Database: RefSeq
Entry: NC_000913
LinkDB: NC_000913
Original site: NC_000913 
LOCUS       NC_000913            4641652 bp    DNA     circular CON 26-AUG-2014
DEFINITION  Escherichia coli str. K-12 substr. MG1655, complete genome.
ACCESSION   NC_000913
VERSION     NC_000913.3  GI:556503834
DBLINK      BioProject: PRJNA57779
            BioSample: SAMN02604091
KEYWORDS    RefSeq.
SOURCE      Escherichia coli str. K-12 substr. MG1655
  ORGANISM  Escherichia coli str. K-12 substr. MG1655
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacteriales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 4641652)
  AUTHORS   Riley,M., Abe,T., Arnaud,M.B., Berlyn,M.K., Blattner,F.R.,
            Chaudhuri,R.R., Glasner,J.D., Horiuchi,T., Keseler,I.M., Kosuge,T.,
            Mori,H., Perna,N.T., Plunkett,G. III, Rudd,K.E., Serres,M.H.,
            Thomas,G.H., Thomson,N.R., Wishart,D. and Wanner,B.L.
  TITLE     Escherichia coli K-12: a cooperatively developed annotation
            snapshot--2005
  JOURNAL   Nucleic Acids Res. 34 (1), 1-9 (2006)
   PUBMED   16397293
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4641652)
  AUTHORS   Hayashi,K., Morooka,N., Yamamoto,Y., Fujita,K., Isono,K., Choi,S.,
            Ohtsubo,E., Baba,T., Wanner,B.L., Mori,H. and Horiuchi,T.
  TITLE     Highly accurate genome sequences of Escherichia coli K-12 strains
            MG1655 and W3110
  JOURNAL   Mol. Syst. Biol. 2, 2006 (2006)
   PUBMED   16738553
REFERENCE   3  (bases 1 to 4641652)
  AUTHORS   Blattner,F.R., Plunkett,G. III, Bloch,C.A., Perna,N.T., Burland,V.,
            Riley,M., Collado-Vides,J., Glasner,J.D., Rode,C.K., Mayhew,G.F.,
            Gregor,J., Davis,N.W., Kirkpatrick,H.A., Goeden,M.A., Rose,D.J.,
            Mau,B. and Shao,Y.
  TITLE     The complete genome sequence of Escherichia coli K-12
  JOURNAL   Science 277 (5331), 1453-1462 (1997)
   PUBMED   9278503
REFERENCE   4  (bases 1 to 4641652)
  AUTHORS   Arnaud,M., Berlyn,M.K.B., Blattner,F.R., Galperin,M.Y.,
            Glasner,J.D., Horiuchi,T., Kosuge,T., Mori,H., Perna,N.T.,
            Plunkett,G. III, Riley,M., Rudd,K.E., Serres,M.H., Thomas,G.H. and
            Wanner,B.L.
  TITLE     Workshop on Annotation of Escherichia coli K-12
  JOURNAL   Unpublished
  REMARK    Woods Hole, Mass., on 14-18 November 2003 (sequence corrections)
REFERENCE   5  (bases 1 to 4641652)
  AUTHORS   Glasner,J.D., Perna,N.T., Plunkett,G. III, Anderson,B.D.,
            Bockhorst,J., Hu,J.C., Riley,M., Rudd,K.E. and Serres,M.H.
  TITLE     ASAP: Escherichia coli K-12 strain MG1655 version m56
  JOURNAL   Unpublished
  REMARK    ASAP download 10 June 2004 (annotation updates)
REFERENCE   6  (bases 1 to 4641652)
  AUTHORS   Hayashi,K., Morooka,N., Mori,H. and Horiuchi,T.
  TITLE     A more accurate sequence comparison between genomes of Escherichia
            coli K12 W3110 and MG1655 strains
  JOURNAL   Unpublished
  REMARK    GenBank accessions AG613214 to AG613378 (sequence corrections)
REFERENCE   7  (bases 1 to 4641652)
  AUTHORS   Perna,N.T.
  TITLE     Escherichia coli K-12 MG1655 yqiK-rfaE intergenic region, genomic
            sequence correction
  JOURNAL   Unpublished
  REMARK    GenBank accession AY605712 (sequence corrections)
REFERENCE   8  (bases 1 to 4641652)
  AUTHORS   Rudd,K.E.
  TITLE     A manual approach to accurate translation start site annotation: an
            E. coli K-12 case study
  JOURNAL   Unpublished
REFERENCE   9  (bases 1 to 4641652)
  CONSRTM   NCBI Genome Project
  TITLE     Direct Submission
  JOURNAL   Submitted (26-AUG-2014) National Center for Biotechnology
            Information, NIH, Bethesda, MD 20894, USA
REFERENCE   10 (bases 1 to 4641652)
  AUTHORS   Blattner,F.R. and Plunkett,G. III.
  TITLE     Direct Submission
  JOURNAL   Submitted (30-JUL-2014) Laboratory of Genetics, University of
            Wisconsin, 425G Henry Mall, Madison, WI 53706-1580, USA
  REMARK    Protein update by submitter
REFERENCE   11 (bases 1 to 4641652)
  AUTHORS   Blattner,F.R. and Plunkett,G. III.
  TITLE     Direct Submission
  JOURNAL   Submitted (15-NOV-2013) Laboratory of Genetics, University of
            Wisconsin, 425G Henry Mall, Madison, WI 53706-1580, USA
  REMARK    Protein update by submitter
REFERENCE   12 (bases 1 to 4641652)
  AUTHORS   Blattner,F.R. and Plunkett,G. III.
  TITLE     Direct Submission
  JOURNAL   Submitted (26-SEP-2013) Laboratory of Genetics, University of
            Wisconsin, 425G Henry Mall, Madison, WI 53706-1580, USA
  REMARK    Sequence update by submitter
REFERENCE   13 (bases 1 to 4641652)
  AUTHORS   Rudd,K.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-FEB-2013) Department of Biochemistry and Molecular
            Biology, University of Miami Miller School of Medicine, 118 Gautier
            Bldg., Miami, FL 33136, USA
  REMARK    Sequence update by submitter
REFERENCE   14 (bases 1 to 4641652)
  AUTHORS   Rudd,K.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (24-APR-2007) Department of Biochemistry and Molecular
            Biology, University of Miami Miller School of Medicine, 118 Gautier
            Bldg., Miami, FL 33136, USA
  REMARK    Annotation update from ecogene.org as a multi-database
            collaboration
REFERENCE   15 (bases 1 to 4641652)
  AUTHORS   Plunkett,G. III.
  TITLE     Direct Submission
  JOURNAL   Submitted (07-FEB-2006) Laboratory of Genetics, University of
            Wisconsin, 425G Henry Mall, Madison, WI 53706-1580, USA
  REMARK    Protein updates by submitter
REFERENCE   16 (bases 1 to 4641652)
  AUTHORS   Plunkett,G. III.
  TITLE     Direct Submission
  JOURNAL   Submitted (10-JUN-2004) Laboratory of Genetics, University of
            Wisconsin, 425G Henry Mall, Madison, WI 53706-1580, USA
  REMARK    Sequence update by submitter
REFERENCE   17 (bases 1 to 4641652)
  AUTHORS   Plunkett,G. III.
  TITLE     Direct Submission
  JOURNAL   Submitted (13-OCT-1998) Laboratory of Genetics, University of
            Wisconsin, 425G Henry Mall, Madison, WI 53706-1580, USA
REFERENCE   18 (bases 1 to 4641652)
  AUTHORS   Blattner,F.R. and Plunkett,G. III.
  TITLE     Direct Submission
  JOURNAL   Submitted (02-SEP-1997) Laboratory of Genetics, University of
            Wisconsin, 425G Henry Mall, Madison, WI 53706-1580, USA
REFERENCE   19 (bases 1 to 4641652)
  AUTHORS   Blattner,F.R. and Plunkett,G. III.
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-1997) Laboratory of Genetics, University of
            Wisconsin, 425G Henry Mall, Madison, WI 53706-1580, USA
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence is identical to U00096.
            On Nov 3, 2013 this sequence version replaced gi:49175990.
            Current U00096 annotation updates are derived from EcoGene
            http://ecogene.org. Suggestions for updates can be sent to Dr.
            Kenneth Rudd (krudd@miami.edu). These updates are being generated
            from a collaboration that also includes ASAP/ERIC, the Coli Genetic
            Stock Center, EcoliHub, EcoCyc, RegulonDB and UniProtKB/Swiss-Prot.
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..4641652
                     /organism="Escherichia coli str. K-12 substr. MG1655"
                     /mol_type="genomic DNA"
                     /strain="K-12"
                     /sub_strain="MG1655"
                     /db_xref="taxon:511145"
     gene            190..255
                     /gene="thrL"
                     /locus_tag="b0001"
                     /gene_synonym="ECK0001; JW4367"
                     /db_xref="EcoGene:EG11277"
                     /db_xref="GeneID:944742"
     CDS             190..255
                     /gene="thrL"
                     /locus_tag="b0001"
                     /gene_synonym="ECK0001; JW4367"
                     /function="leader; Amino acid biosynthesis: Threonine"
                     /GO_process="GO:0009088 - threonine biosynthetic process"
                     /codon_start=1
                     /transl_table=11
                     /product="thr operon leader peptide"
                     /protein_id="NP_414542.1"
                     /db_xref="GI:16127995"
                     /db_xref="ASAP:ABE-0000006"
                     /db_xref="UniProtKB/Swiss-Prot:P0AD86"
                     /db_xref="EcoGene:EG11277"
                     /db_xref="GeneID:944742"
                     /translation="MKRISTTITTTITITTGNGAG"
     gene            337..2799
                     /gene="thrA"
                     /locus_tag="b0002"
                     /gene_synonym="ECK0002; Hs; JW0001; thrA1; thrA2; thrD"
                     /db_xref="EcoGene:EG10998"
                     /db_xref="GeneID:945803"
     CDS             337..2799
                     /gene="thrA"
                     /locus_tag="b0002"
                     /gene_synonym="ECK0002; Hs; JW0001; thrA1; thrA2; thrD"
                     /EC_number="1.1.1.3"
                     /EC_number="2.7.2.4"
                     /function="enzyme; Amino acid biosynthesis: Threonine"
                     /experiment="N-terminus verified by Edman degradation:
                     PMID 354697,4562989"
                     /GO_component="GO:0005737 - cytoplasm"
                     /GO_process="GO:0009088 - threonine biosynthetic process"
                     /GO_process="GO:0009086 - methionine biosynthetic process"
                     /GO_process="GO:0009090 - homoserine biosynthetic process"
                     /note="bifunctional: aspartokinase I (N-terminal);
                     homoserine dehydrogenase I (C-terminal)"
                     /codon_start=1
                     /transl_table=11
                     /product="Bifunctional aspartokinase/homoserine
                     dehydrogenase 1"
                     /protein_id="NP_414543.1"
                     /db_xref="GI:16127996"
                     /db_xref="ASAP:ABE-0000008"
                     /db_xref="UniProtKB/Swiss-Prot:P00561"
                     /db_xref="EcoGene:EG10998"
                     /db_xref="GeneID:945803"
                     /translation="MRVLKFGGTSVANAERFLRVADILESNARQGQVATVLSAPAKIT
                     NHLVAMIEKTISGQDALPNISDAERIFAELLTGLAAAQPGFPLAQLKTFVDQEFAQIK
                     HVLHGISLLGQCPDSINAALICRGEKMSIAIMAGVLEARGHNVTVIDPVEKLLAVGHY
                     LESTVDIAESTRRIAASRIPADHMVLMAGFTAGNEKGELVVLGRNGSDYSAAVLAACL
                     RADCCEIWTDVDGVYTCDPRQVPDARLLKSMSYQEAMELSYFGAKVLHPRTITPIAQF
                     QIPCLIKNTGNPQAPGTLIGASRDEDELPVKGISNLNNMAMFSVSGPGMKGMVGMAAR
                     VFAAMSRARISVVLITQSSSEYSISFCVPQSDCVRAERAMQEEFYLELKEGLLEPLAV
                     TERLAIISVVGDGMRTLRGISAKFFAALARANINIVAIAQGSSERSISVVVNNDDATT
                     GVRVTHQMLFNTDQVIEVFVIGVGGVGGALLEQLKRQQSWLKNKHIDLRVCGVANSKA
                     LLTNVHGLNLENWQEELAQAKEPFNLGRLIRLVKEYHLLNPVIVDCTSSQAVADQYAD
                     FLREGFHVVTPNKKANTSSMDYYHQLRYAAEKSRRKFLYDTNVGAGLPVIENLQNLLN
                     AGDELMKFSGILSGSLSYIFGKLDEGMSFSEATTLAREMGYTEPDPRDDLSGMDVARK
                     LLILARETGRELELADIEIEPVLPAEFNAEGDVAAFMANLSQLDDLFAARVAKARDEG
                     KVLRYVGNIDEDGVCRVKIAEVDGNDPLFKVKNGENALAFYSHYYQPLPLVLRGYGAG
                     NDVTAAGVFADLLRTLSWKLGV"
     misc_feature    337..2796
                     /gene="thrA"
                     /locus_tag="b0002"
                     /gene_synonym="ECK0002; Hs; JW0001; thrA1; thrA2; thrD"
                     /note="bifunctional aspartokinase I/homoserine
                     dehydrogenase I; Provisional; Region: thrA; PRK09436"
                     /db_xref="CDD:181856"
     misc_feature    337..1224
                     /gene="thrA"
                     /locus_tag="b0002"
                     /gene_synonym="ECK0002; Hs; JW0001; thrA1; thrA2; thrD"
                     /note="AAK_AK-HSDH: Amino Acid Kinase Superfamily (AAK),
                     AK-HSDH; this CD includes the N-terminal catalytic domain
                     of aspartokinase (AK) of the bifunctional enzyme AK -
                     homoserine dehydrogenase (HSDH). These aspartokinases are
                     found in bacteria (E. coli...; Region: AAK_AK-HSDH;
                     cd04257"
                     /db_xref="CDD:239790"
     misc_feature    order(349..351,466..468,715..717,958..960,1093..1095,
                     1132..1134)
                     /gene="thrA"
                     /locus_tag="b0002"
                     /gene_synonym="ECK0002; Hs; JW0001; thrA1; thrA2; thrD"
                     /note="putative catalytic residues [active]"
                     /db_xref="CDD:239790"
     misc_feature    order(349..351,355..363,1018..1023,1030..1035)
                     /gene="thrA"
                     /locus_tag="b0002"
                     /gene_synonym="ECK0002; Hs; JW0001; thrA1; thrA2; thrD"
                     /note="putative nucleotide binding site [chemical
                     binding]; other site"
                     /db_xref="CDD:239790"
     misc_feature    order(448..453,466..468,715..717)
                     /gene="thrA"
                     /locus_tag="b0002"
                     /gene_synonym="ECK0002; Hs; JW0001; thrA1; thrA2; thrD"
                     /note="putative aspartate binding site [chemical binding];
                     other site"
                     /db_xref="CDD:239790"
     misc_feature    1279..1518
                     /gene="thrA"
                     /locus_tag="b0002"
                     /gene_synonym="ECK0002; Hs; JW0001; thrA1; thrA2; thrD"
                     /note="ACT domains of the bifunctional enzyme
                     aspartokinase (AK) - homoserine dehydrogenase (HSDH);
                     Region: ACT_AKi-HSDH-ThrA-like_1; cd04921"
                     /db_xref="CDD:153193"
     misc_feature    order(1303..1311,1318..1323,1333..1335,1342..1347,
                     1366..1368,1372..1392,1396..1401,1405..1407,1411..1413)
                     /gene="thrA"
                     /locus_tag="b0002"
                     /gene_synonym="ECK0002; Hs; JW0001; thrA1; thrA2; thrD"
                     /note="dimer interface [polypeptide binding]; other site"
                     /db_xref="CDD:153193"
     misc_feature    1387..1389
                     /gene="thrA"
                     /locus_tag="b0002"
                     /gene_synonym="ECK0002; Hs; JW0001; thrA1; thrA2; thrD"
                     /note="putative threonine allosteric regulatory site;
                     other site"
                     /db_xref="CDD:153193"
     misc_feature    1522..1719
                     /gene="thrA"
                     /locus_tag="b0002"
                     /gene_synonym="ECK0002; Hs; JW0001; thrA1; thrA2; thrD"
                     /note="ACT domains of the bifunctional enzyme
                     aspartokinase (AK) - homoserine dehydrogenase (HSDH);
                     Region: ACT_AKi-HSDH-ThrA_2; cd04922"
                     /db_xref="CDD:153194"
     misc_feature    1630..1632
                     /gene="thrA"
                     /locus_tag="b0002"
                     /gene_synonym="ECK0002; Hs; JW0001; thrA1; thrA2; thrD"
                     /note="putative threonine allosteric regulatory site;
                     other site"
                     /db_xref="CDD:153194"
     misc_feature    1771..2151
                     /gene="thrA"
                     /locus_tag="b0002"
                     /gene_synonym="ECK0002; Hs; JW0001; thrA1; thrA2; thrD"
                     /note="Homoserine dehydrogenase, NAD binding domain;
                     Region: NAD_binding_3; pfam03447"
                     /db_xref="CDD:251960"
     misc_feature    2176..2769
                     /gene="thrA"
                     /locus_tag="b0002"
                     /gene_synonym="ECK0002; Hs; JW0001; thrA1; thrA2; thrD"
                     /note="Homoserine dehydrogenase; Region: Homoserine_dh;
                     pfam00742"
                     /db_xref="CDD:250099"
     gene            2801..3733
                     /gene="thrB"
                     /locus_tag="b0003"
                     /gene_synonym="ECK0003; JW0002"
                     /db_xref="EcoGene:EG10999"
                     /db_xref="GeneID:947498"
     CDS             2801..3733
                     /gene="thrB"
                     /locus_tag="b0003"
                     /gene_synonym="ECK0003; JW0002"
                     /EC_number="2.7.1.39"
                     /function="enzyme; Amino acid biosynthesis: Threonine"
                     /GO_component="GO:0005737 - cytoplasm"
                     /GO_process="GO:0009088 - threonine biosynthetic process"
                     /codon_start=1
                     /transl_table=11
                     /product="homoserine kinase"
                     /protein_id="NP_414544.1"
                     /db_xref="GI:16127997"
                     /db_xref="ASAP:ABE-0000010"
                     /db_xref="UniProtKB/Swiss-Prot:P00547"
                     /db_xref="EcoGene:EG10999"
                     /db_xref="GeneID:947498"
                     /translation="MVKVYAPASSANMSVGFDVLGAAVTPVDGALLGDVVTVEAAETF
                     SLNNLGRFADKLPSEPRENIVYQCWERFCQELGKQIPVAMTLEKNMPIGSGLGSSACS
                     VVAALMAMNEHCGKPLNDTRLLALMGELEGRISGSIHYDNVAPCFLGGMQLMIEENDI
                     ISQQVPGFDEWLWVLAYPGIKVSTAEARAILPAQYRRQDCIAHGRHLAGFIHACYSRQ
                     PELAAKLMKDVIAEPYRERLLPGFRQARQAVAEIGAVASGISGSGPTLFALCDKPETA
                     QRVADWLGKNYLQNQEGFVHICRLDTAGARVLEN"
     misc_feature    2804..3724
                     /gene="thrB"
                     /locus_tag="b0003"
                     /gene_synonym="ECK0003; JW0002"
                     /note="homoserine kinase; Region: thrB; TIGR00191"
                     /db_xref="CDD:129295"
     misc_feature    <2810..3160
                     /gene="thrB"
                     /locus_tag="b0003"
                     /gene_synonym="ECK0003; JW0002"
                     /note="Protein of unknown function; Region: YhfT;
                     pfam10797"
                     /db_xref="CDD:256168"
     misc_feature    3050..3250
                     /gene="thrB"
                     /locus_tag="b0003"
                     /gene_synonym="ECK0003; JW0002"
                     /note="GHMP kinases N terminal domain; Region:
                     GHMP_kinases_N; pfam00288"
                     /db_xref="CDD:249743"
     misc_feature    3428..3661
                     /gene="thrB"
                     /locus_tag="b0003"
                     /gene_synonym="ECK0003; JW0002"
                     /note="GHMP kinases C terminal; Region: GHMP_kinases_C;
                     pfam08544"
                     /db_xref="CDD:254869"
     gene            3734..5020
                     /gene="thrC"
                     /locus_tag="b0004"
                     /gene_synonym="ECK0004; JW0003"
                     /db_xref="EcoGene:EG11000"
                     /db_xref="GeneID:945198"
     CDS             3734..5020
                     /gene="thrC"
                     /locus_tag="b0004"
                     /gene_synonym="ECK0004; JW0003"
                     /EC_number="4.2.3.1"
                     /function="enzyme; Amino acid biosynthesis: Threonine"
                     /experiment="N-terminus verified by Edman degradation:
                     PMID 9298646,9600841,9740056"
                     /GO_component="GO:0005737 - cytoplasm"
                     /GO_process="GO:0009088 - threonine biosynthetic process"
                     /codon_start=1
                     /transl_table=11
                     /product="L-threonine synthase"
                     /protein_id="NP_414545.1"
                     /db_xref="GI:16127998"
                     /db_xref="ASAP:ABE-0000012"
                     /db_xref="UniProtKB/Swiss-Prot:P00934"
                     /db_xref="EcoGene:EG11000"
                     /db_xref="GeneID:945198"
                     /translation="MKLYNLKDHNEQVSFAQAVTQGLGKNQGLFFPHDLPEFSLTEID
                     EMLKLDFVTRSAKILSAFIGDEIPQEILEERVRAAFAFPAPVANVESDVGCLELFHGP
                     TLAFKDFGGRFMAQMLTHIAGDKPVTILTATSGDTGAAVAHAFYGLPNVKVVILYPRG
                     KISPLQEKLFCTLGGNIETVAIDGDFDACQALVKQAFDDEELKVALGLNSANSINISR
                     LLAQICYYFEAVAQLPQETRNQLVVSVPSGNFGDLTAGLLAKSLGLPVKRFIAATNVN
                     DTVPRFLHDGQWSPKATQATLSNAMDVSQPNNWPRVEELFRRKIWQLKELGYAAVDDE
                     TTQQTMRELKELGYTSEPHAAVAYRALRDQLNPGEYGLFLGTAHPAKFKESVEAILGE
                     TLDLPKELAERADLPLLSHNLPADFAALRKLMMNHQ"
     misc_feature    3734..5017
                     /gene="thrC"
                     /locus_tag="b0004"
                     /gene_synonym="ECK0004; JW0003"
                     /note="threonine synthase; Validated; Region: PRK09225"
                     /db_xref="CDD:236418"
     misc_feature    3737..5002
                     /gene="thrC"
                     /locus_tag="b0004"
                     /gene_synonym="ECK0004; JW0003"
                     /note="Threonine synthase catalyzes the final step of
                     threonine biosynthesis. The conversion of
                     O-phosphohomoserine into threonine and inorganic phosphate
                     is pyridoxal 5'-phosphate dependent. The Thr-synth_1 CD
                     includes members from higher plants; Region: Thr-synth_2;
                     cd01560"
                     /db_xref="CDD:107203"
     misc_feature    order(4052..4054,4475..4480,4859..4861)
                     /gene="thrC"
                     /locus_tag="b0004"
                     /gene_synonym="ECK0004; JW0003"
                     /note="pyridoxal 5'-phosphate binding site [chemical
                     binding]; other site"
                     /db_xref="CDD:107203"
     misc_feature    4052..4054
                     /gene="thrC"
                     /locus_tag="b0004"
                     /gene_synonym="ECK0004; JW0003"
                     /note="catalytic residue [active]"
                     /db_xref="CDD:107203"
     gene            5234..5530
                     /gene="yaaX"
                     /locus_tag="b0005"
                     /gene_synonym="ECK0005; JW0004"
                     /db_xref="EcoGene:EG14384"
                     /db_xref="GeneID:944747"
     CDS             5234..5530
                     /gene="yaaX"
                     /locus_tag="b0005"
                     /gene_synonym="ECK0005; JW0004"
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2502 family putative periplasmic protein"
                     /protein_id="NP_414546.1"
                     /db_xref="GI:16127999"
                     /db_xref="ASAP:ABE-0000015"
                     /db_xref="UniProtKB/Swiss-Prot:P75616"
                     /db_xref="EcoGene:EG14384"
                     /db_xref="GeneID:944747"
                     /translation="MKKMQSIVLALSLVLVAPMAAQAAEITLVPSVKLQIGDRDNRGY
                     YWDGGHWRDHGWWKQHYEWRGNRWHLHGPPPPPRHHKKAPHDHHGGHGPGKHHR"
     misc_feature    5306..5485
                     /gene="yaaX"
                     /locus_tag="b0005"
                     /gene_synonym="ECK0005; JW0004"
                     /note="Protein of unknown function (DUF2502); Region:
                     DUF2502; pfam10697"
                     /db_xref="CDD:256125"
     repeat_region   5565..5669
                     /note="RIP1 (repetitive extragenic palindromic) element;
                     contains 2 REP sequences and 1 IHF site"
     gene            complement(5683..6459)
                     /gene="yaaA"
                     /locus_tag="b0006"
                     /gene_synonym="ECK0006; JW0005"
                     /db_xref="EcoGene:EG10011"
                     /db_xref="GeneID:944749"
     CDS             complement(5683..6459)
                     /gene="yaaA"
                     /locus_tag="b0006"
                     /gene_synonym="ECK0006; JW0005"
                     /codon_start=1
                     /transl_table=11
                     /product="peroxide resistance protein, lowers
                     intracellular iron"
                     /protein_id="NP_414547.1"
                     /db_xref="GI:16128000"
                     /db_xref="ASAP:ABE-0000018"
                     /db_xref="UniProtKB/Swiss-Prot:P0A8I3"
                     /db_xref="EcoGene:EG10011"
                     /db_xref="GeneID:944749"
                     /translation="MLILISPAKTLDYQSPLTTTRYTLPELLDNSQQLIHEARKLTPP
                     QISTLMRISDKLAGINAARFHDWQPDFTPANARQAILAFKGDVYTGLQAETFSEDDFD
                     FAQQHLRMLSGLYGVLRPLDLMQPYRLEMGIRLENARGKDLYQFWGDIITNKLNEALA
                     AQGDNVVINLASDEYFKSVKPKKLNAEIIKPVFLDEKNGKFKIISFYAKKARGLMSRF
                     IIENRLTKPEQLTGFNSEGYFFDEDSSSNGELVFKRYEQR"
     misc_feature    complement(5689..6459)
                     /gene="yaaA"
                     /locus_tag="b0006"
                     /gene_synonym="ECK0006; JW0005"
                     /note="hypothetical protein; Validated; Region: PRK02101"
                     /db_xref="CDD:234999"
     gene            complement(6529..7959)
                     /gene="yaaJ"
                     /locus_tag="b0007"
                     /gene_synonym="ECK0007; JW0006"
                     /db_xref="EcoGene:EG11555"
                     /db_xref="GeneID:944745"
     CDS             complement(6529..7959)
                     /gene="yaaJ"
                     /locus_tag="b0007"
                     /gene_synonym="ECK0007; JW0006"
                     /function="putative transport; Transport of small
                     molecules: Amino acids, amines"
                     /GO_component="GO:0009274 - peptidoglycan-based cell wall"
                     /GO_component="GO:0019866 - organelle inner membrane"
                     /note="inner membrane transport protein"
                     /codon_start=1
                     /transl_table=11
                     /product="putative transporter"
                     /protein_id="NP_414548.1"
                     /db_xref="GI:16128001"
                     /db_xref="ASAP:ABE-0000020"
                     /db_xref="UniProtKB/Swiss-Prot:P30143"
                     /db_xref="EcoGene:EG11555"
                     /db_xref="GeneID:944745"
                     /translation="MPDFFSFINSVLWGSVMIYLLFGAGCWFTFRTGFVQFRYIRQFG
                     KSLKNSIHPQPGGLTSFQSLCTSLAARVGSGNLAGVALAITAGGPGAVFWMWVAAFIG
                     MATSFAECSLAQLYKERDVNGQFRGGPAWYMARGLGMRWMGVLFAVFLLIAYGIIFSG
                     VQANAVARALSFSFDFPPLVTGIILAVFTLLAITRGLHGVARLMQGFVPLMAIIWVLT
                     SLVICVMNIGQLPHVIWSIFESAFGWQEAAGGAAGYTLSQAITNGFQRSMFSNEAGMG
                     STPNAAAAAASWPPHPAAQGIVQMIGIFIDTLVICTASAMLILLAGNGTTYMPLEGIQ
                     LIQKAMRVLMGSWGAEFVTLVVILFAFSSIVANYIYAENNLFFLRLNNPKAIWCLRIC
                     TFATVIGGTLLSLPLMWQLADIIMACMAITNLTAILLLSPVVHTIASDYLRQRKLGVR
                     PVFDPLRYPDIGRQLSPDAWDDVSQE"
     misc_feature    complement(6586..7818)
                     /gene="yaaJ"
                     /locus_tag="b0007"
                     /gene_synonym="ECK0007; JW0006"
                     /note="Sodium:alanine symporter family; Region:
                     Na_Ala_symp; pfam01235"
                     /db_xref="CDD:250465"
     gene            8238..9191
                     /gene="talB"
                     /locus_tag="b0008"
                     /gene_synonym="ECK0008; JW0007; yaaK"
                     /db_xref="EcoGene:EG11556"
                     /db_xref="GeneID:944748"
     CDS             8238..9191
                     /gene="talB"
                     /locus_tag="b0008"
                     /gene_synonym="ECK0008; JW0007; yaaK"
                     /EC_number="2.2.1.2"
                     /function="enzyme; Central intermediary metabolism:
                     Non-oxidative branch, pentose pathway"
                     /GO_component="GO:0005737 - cytoplasm"
                     /GO_process="GO:0009052 - pentose-phosphate shunt,
                     non-oxidative branch"
                     /codon_start=1
                     /transl_table=11
                     /product="transaldolase B"
                     /protein_id="NP_414549.1"
                     /db_xref="GI:16128002"
                     /db_xref="ASAP:ABE-0000027"
                     /db_xref="UniProtKB/Swiss-Prot:P0A870"
                     /db_xref="EcoGene:EG11556"
                     /db_xref="GeneID:944748"
                     /translation="MTDKLTSLRQYTTVVADTGDIAAMKLYQPQDATTNPSLILNAAQ
                     IPEYRKLIDDAVAWAKQQSNDRAQQIVDATDKLAVNIGLEILKLVPGRISTEVDARLS
                     YDTEASIAKAKRLIKLYNDAGISNDRILIKLASTWQGIRAAEQLEKEGINCNLTLLFS
                     FAQARACAEAGVFLISPFVGRILDWYKANTDKKEYAPAEDPGVVSVSEIYQYYKEHGY
                     ETVVMGASFRNIGEILELAGCDRLTIAPALLKELAESEGAIERKLSYTGEVKARPARI
                     TESEFLWQHNQDPMAVDKLAEGIRKFAIDQEKLEKMIGDLL"
     misc_feature    8238..9188
                     /gene="talB"
                     /locus_tag="b0008"
                     /gene_synonym="ECK0008; JW0007; yaaK"
                     /note="transaldolase-like protein; Provisional; Region:
                     PTZ00411"
                     /db_xref="CDD:240406"
     misc_feature    8247..9176
                     /gene="talB"
                     /locus_tag="b0008"
                     /gene_synonym="ECK0008; JW0007; yaaK"
                     /note="Transaldolases including both TalA and TalB;
                     Region: Transaldolase_TalAB; cd00957"
                     /db_xref="CDD:188644"
     misc_feature    order(8286..8288,8334..8336,8340..8345,8517..8519,
                     8523..8525,8631..8633,8697..8699,8703..8705,8763..8765,
                     8778..8780)
                     /gene="talB"
                     /locus_tag="b0008"
                     /gene_synonym="ECK0008; JW0007; yaaK"
                     /note="active site"
                     /db_xref="CDD:188644"
     misc_feature    order(8547..8549,9072..9074,9081..9083,9093..9098,
                     9114..9116,9123..9125,9135..9137)
                     /gene="talB"
                     /locus_tag="b0008"
                     /gene_synonym="ECK0008; JW0007; yaaK"
                     /note="dimer interface [polypeptide binding]; other site"
                     /db_xref="CDD:188644"
     misc_feature    8631..8633
                     /gene="talB"
                     /locus_tag="b0008"
                     /gene_synonym="ECK0008; JW0007; yaaK"
                     /note="catalytic residue [active]"
                     /db_xref="CDD:188644"
     gene            9306..9893
                     /gene="mog"
                     /locus_tag="b0009"
                     /gene_synonym="bisD; chlG; ECK0009; JW0008; mogA; yaaG"
                     /db_xref="EcoGene:EG11511"
                     /db_xref="GeneID:944760"
     CDS             9306..9893
                     /gene="mog"
                     /locus_tag="b0009"
                     /gene_synonym="bisD; chlG; ECK0009; JW0008; mogA; yaaG"
                     /function="transport; Biosynthesis of cofactors, carriers:
                     Molybdopterin"
                     /GO_component="GO:0005737 - cytoplasm"
                     /GO_process="GO:0006777 - Mo-molybdopterin cofactor
                     biosynthetic process"
                     /note="putative molybdochetalase in molybdopterine
                     biosynthesis"
                     /codon_start=1
                     /transl_table=11
                     /product="molybdochelatase incorporating molybdenum into
                     molybdopterin"
                     /protein_id="NP_414550.1"
                     /db_xref="GI:16128003"
                     /db_xref="ASAP:ABE-0000030"
                     /db_xref="UniProtKB/Swiss-Prot:P0AF03"
                     /db_xref="EcoGene:EG11511"
                     /db_xref="GeneID:944760"
                     /translation="MNTLRIGLVSISDRASSGVYQDKGIPALEEWLTSALTTPFELET
                     RLIPDEQAIIEQTLCELVDEMSCHLVLTTGGTGPARRDVTPDATLAVADREMPGFGEQ
                     MRQISLHFVPTAILSRQVGVIRKQALILNLPGQPKSIKETLEGVKDAEGNVVVHGIFA
                     SVPYCIQLLEGPYVETAPEVVAAFRPKSARRDVSE"
     misc_feature    9315..9812
                     /gene="mog"
                     /locus_tag="b0009"
                     /gene_synonym="bisD; chlG; ECK0009; JW0008; mogA; yaaG"
                     /note="MogA_MoaB family. Members of this family are
                     involved in biosynthesis of the molybdenum cofactor (MoCF)
                     an essential cofactor of a diverse group of redox enzymes.
                     MoCF biosynthesis is an evolutionarily conserved pathway
                     present in eubacteria, archaea; Region: MogA_MoaB;
                     cd00886"
                     /db_xref="CDD:238451"
     misc_feature    order(9528..9536,9624..9626,9702..9707,9717..9719,
                     9726..9728)
                     /gene="mog"
                     /locus_tag="b0009"
                     /gene_synonym="bisD; chlG; ECK0009; JW0008; mogA; yaaG"
                     /note="MPT binding site; other site"
                     /db_xref="CDD:238451"
     misc_feature    order(9534..9536,9540..9545,9549..9551,9561..9563,
                     9585..9593,9606..9608,9615..9620,9648..9650,9657..9659,
                     9810..9812)
                     /gene="mog"
                     /locus_tag="b0009"
                     /gene_synonym="bisD; chlG; ECK0009; JW0008; mogA; yaaG"
                     /note="trimer interface [polypeptide binding]; other site"
                     /db_xref="CDD:238451"
     gene            complement(9928..10494)
                     /gene="satP"
                     /locus_tag="b0010"
                     /gene_synonym="ECK0010; JW0009; yaaH"
                     /db_xref="EcoGene:EG11512"
                     /db_xref="GeneID:944792"
     CDS             complement(9928..10494)
                     /gene="satP"
                     /locus_tag="b0010"
                     /gene_synonym="ECK0010; JW0009; yaaH"
                     /codon_start=1
                     /transl_table=11
                     /product="succinate-acetate transporter"
                     /protein_id="NP_414551.1"
                     /db_xref="GI:16128004"
                     /db_xref="ASAP:ABE-0000032"
                     /db_xref="UniProtKB/Swiss-Prot:P0AC98"
                     /db_xref="EcoGene:EG11512"
                     /db_xref="GeneID:944792"
                     /translation="MGNTKLANPAPLGLMGFGMTTILLNLHNVGYFALDGIILAMGIF
                     YGGIAQIFAGLLEYKKGNTFGLTAFTSYGSFWLTLVAILLMPKLGLTDAPNAQFLGVY
                     LGLWGVFTLFMFFGTLKGARVLQFVFFSLTVLFALLAIGNIAGNAAIIHFAGWIGLIC
                     GASAIYLAMGEVLNEQFGRTVLPIGESH"
     misc_feature    complement(9931..10494)
                     /gene="satP"
                     /locus_tag="b0010"
                     /gene_synonym="ECK0010; JW0009; yaaH"
                     /note="hypothetical protein; Provisional; Region:
                     PRK10659"
                     /db_xref="CDD:182625"
     gene            complement(10643..11356)
                     /gene="yaaW"
                     /locus_tag="b0011"
                     /gene_synonym="ECK0011; JW0010"
                     /db_xref="EcoGene:EG14340"
                     /db_xref="GeneID:944771"
     CDS             complement(10643..11356)
                     /gene="yaaW"
                     /locus_tag="b0011"
                     /gene_synonym="ECK0011; JW0010"
                     /function="putative enzyme; Not classified"
                     /codon_start=1
                     /transl_table=11
                     /product="UPF0174 family protein"
                     /protein_id="NP_414552.1"
                     /db_xref="GI:16128005"
                     /db_xref="ASAP:ABE-0000037"
                     /db_xref="UniProtKB/Swiss-Prot:P75617"
                     /db_xref="EcoGene:EG14340"
                     /db_xref="GeneID:944771"
                     /translation="MNVNYLNDSDLDFLQHCSEEQLANFARLLTHNEKGKTRLSSVLM
                     RNELFKSMEGHPEQHRRNWQLIAGELQHFGGDSIANKLRGHGKLYRAILLDVSKRLKL
                     KADKEMSTFEIEQQLLEQFLRNTWKKMDEEHKQEFLHAVDARVNELEELLPLLMKDKL
                     LAKGVSHLLSSQLTRILRTHAAMSVLGHGLLRGAGLGGPVGAALNGVKAVSGSAYRVT
                     IPAVLQIACLRRMVSATQV"
     misc_feature    complement(10646..11356)
                     /gene="yaaW"
                     /locus_tag="b0011"
                     /gene_synonym="ECK0011; JW0010"
                     /note="hypothetical protein; Provisional; Region:
                     PRK10236"
                     /db_xref="CDD:182323"
     misc_feature    complement(11240..11344)
                     /gene="yaaW"
                     /locus_tag="b0011"
                     /gene_synonym="ECK0011; JW0010"
                     /note="Domain of unknown function (DUF3944); Region:
                     DUF3944; pfam13099"
                     /db_xref="CDD:257500"
     misc_feature    complement(10646..11242)
                     /gene="yaaW"
                     /locus_tag="b0011"
                     /gene_synonym="ECK0011; JW0010"
                     /note="Uncharacterized protein conserved in bacteria
                     [Function unknown]; Region: COG4735"
                     /db_xref="CDD:227078"
     gene            complement(11382..11786)
                     /gene="yaaI"
                     /locus_tag="b0013"
                     /gene_synonym="ECK0013; JW0012"
                     /db_xref="EcoGene:EG11513"
                     /db_xref="GeneID:944751"
     CDS             complement(11382..11786)
                     /gene="yaaI"
                     /locus_tag="b0013"
                     /gene_synonym="ECK0013; JW0012"
                     /codon_start=1
                     /transl_table=11
                     /product="UPF0412 family protein"
                     /protein_id="NP_414554.1"
                     /db_xref="GI:16128007"
                     /db_xref="ASAP:ABE-0000043"
                     /db_xref="UniProtKB/Swiss-Prot:P28696"
                     /db_xref="EcoGene:EG11513"
                     /db_xref="GeneID:944751"
                     /translation="MKSVFTISASLAISLMLCCTAQANDHKLLGAIAMPRNETNDLAL
                     KLPVCRIVKRIQLSADHGDLQLSGASVYFKAARSASQSLNIPSEIKEGQTTDWININS
                     DNDNKRCVSKITFSGHTVNSSDMATLKIIGDD"
     misc_feature    complement(11385..11786)
                     /gene="yaaI"
                     /locus_tag="b0013"
                     /gene_synonym="ECK0013; JW0012"
                     /note="hypothetical protein; Provisional; Region:
                     PRK10154"
                     /db_xref="CDD:182272"
     gene            12163..14079
                     /gene="dnaK"
                     /locus_tag="b0014"
                     /gene_synonym="ECK0014; groPAB; groPC; groPF; grpC; grpF;
                     JW0013; seg"
                     /db_xref="EcoGene:EG10241"
                     /db_xref="GeneID:944750"
     CDS             12163..14079
                     /gene="dnaK"
                     /locus_tag="b0014"
                     /gene_synonym="ECK0014; groPAB; groPC; groPF; grpC; grpF;
                     JW0013; seg"
                     /function="factor; Chaperones"
                     /GO_component="GO:0005737 - cytoplasm"
                     /GO_process="GO:0006457 - protein folding"
                     /GO_process="GO:0006970 - response to osmotic stress"
                     /note="chaperone Hsp70; DNA biosynthesis; autoregulated
                     heat shock proteins"
                     /codon_start=1
                     /transl_table=11
                     /product="chaperone Hsp70, with co-chaperone DnaJ"
                     /protein_id="NP_414555.1"
                     /db_xref="GI:16128008"
                     /db_xref="ASAP:ABE-0000052"
                     /db_xref="UniProtKB/Swiss-Prot:P0A6Y8"
                     /db_xref="EcoGene:EG10241"
                     /db_xref="GeneID:944750"
                     /translation="MGKIIGIDLGTTNSCVAIMDGTTPRVLENAEGDRTTPSIIAYTQ
                     DGETLVGQPAKRQAVTNPQNTLFAIKRLIGRRFQDEEVQRDVSIMPFKIIAADNGDAW
                     VEVKGQKMAPPQISAEVLKKMKKTAEDYLGEPVTEAVITVPAYFNDAQRQATKDAGRI
                     AGLEVKRIINEPTAAALAYGLDKGTGNRTIAVYDLGGGTFDISIIEIDEVDGEKTFEV
                     LATNGDTHLGGEDFDSRLINYLVEEFKKDQGIDLRNDPLAMQRLKEAAEKAKIELSSA
                     QQTDVNLPYITADATGPKHMNIKVTRAKLESLVEDLVNRSIEPLKVALQDAGLSVSDI
                     DDVILVGGQTRMPMVQKKVAEFFGKEPRKDVNPDEAVAIGAAVQGGVLTGDVKDVLLL
                     DVTPLSLGIETMGGVMTTLIAKNTTIPTKHSQVFSTAEDNQSAVTIHVLQGERKRAAD
                     NKSLGQFNLDGINPAPRGMPQIEVTFDIDADGILHVSAKDKNSGKEQKITIKASSGLN
                     EDEIQKMVRDAEANAEADRKFEELVQTRNQGDHLLHSTRKQVEEAGDKLPADDKTAIE
                     SALTALETALKGEDKAAIEAKMQELAQVSQKLMEIAQQQHAQQQTAGADASANNAKDD
                     DVVDAEFEEVKDKK"
     misc_feature    12163..14076
                     /gene="dnaK"
                     /locus_tag="b0014"
                     /gene_synonym="ECK0014; groPAB; groPC; groPF; grpC; grpF;
                     JW0013; seg"
                     /note="molecular chaperone DnaK; Provisional; Region:
                     dnaK; PRK00290"
                     /db_xref="CDD:234715"
     misc_feature    12163..13308
                     /gene="dnaK"
                     /locus_tag="b0014"
                     /gene_synonym="ECK0014; groPAB; groPC; groPF; grpC; grpF;
                     JW0013; seg"
                     /note="Nucleotide-binding domain of human HSPA9,
                     Escherichia coli DnaK, and similar proteins; Region:
                     HSPA9-like_NBD; cd11733"
                     /db_xref="CDD:212683"
     misc_feature    order(12190..12201,12370..12372,12673..12675,12748..12753,
                     12757..12759,12847..12849,12961..12963,12970..12972,
                     12982..12984,13183..13191,13195..13197)
                     /gene="dnaK"
                     /locus_tag="b0014"
                     /gene_synonym="ECK0014; groPAB; groPC; groPF; grpC; grpF;
                     JW0013; seg"
                     /note="nucleotide binding site [chemical binding]; other
                     site"
                     /db_xref="CDD:212683"
     misc_feature    order(12244..12246,12253..12255,12307..12309,12319..12321,
                     12328..12333,12337..12342,12547..12558,12931..12933,
                     12940..12945,12952..12954,13006..13008,13012..13017)
                     /gene="dnaK"
                     /locus_tag="b0014"
                     /gene_synonym="ECK0014; groPAB; groPC; groPF; grpC; grpF;
                     JW0013; seg"
                     /note="NEF interaction site [polypeptide binding]; other
                     site"
                     /db_xref="CDD:212683"
     misc_feature    order(12604..12609,12613..12618,12661..12666,12670..12672,
                     12808..12819)
                     /gene="dnaK"
                     /locus_tag="b0014"
                     /gene_synonym="ECK0014; groPAB; groPC; groPF; grpC; grpF;
                     JW0013; seg"
                     /note="SBD interface [polypeptide binding]; other site"
                     /db_xref="CDD:212683"
     gene            14168..15298
                     /gene="dnaJ"
                     /locus_tag="b0015"
                     /gene_synonym="ECK0015; faa; groP; grpC; JW0014"
                     /db_xref="EcoGene:EG10240"
                     /db_xref="GeneID:944753"
     CDS             14168..15298
                     /gene="dnaJ"
                     /locus_tag="b0015"
                     /gene_synonym="ECK0015; faa; groP; grpC; JW0014"
                     /function="factor; Chaperones"
                     /GO_component="GO:0005737 - cytoplasm"
                     /GO_process="GO:0006457 - protein folding"
                     /note="chaperone with DnaK; heat shock protein"
                     /codon_start=1
                     /transl_table=11
                     /product="chaperone Hsp40, DnaK co-chaperone"
                     /protein_id="NP_414556.1"
                     /db_xref="GI:16128009"
                     /db_xref="ASAP:ABE-0000054"
                     /db_xref="UniProtKB/Swiss-Prot:P08622"
                     /db_xref="EcoGene:EG10240"
                     /db_xref="GeneID:944753"
                     /translation="MAKQDYYEILGVSKTAEEREIRKAYKRLAMKYHPDRNQGDKEAE
                     AKFKEIKEAYEVLTDSQKRAAYDQYGHAAFEQGGMGGGGFGGGADFSDIFGDVFGDIF
                     GGGRGRQRAARGADLRYNMELTLEEAVRGVTKEIRIPTLEECDVCHGSGAKPGTQPQT
                     CPTCHGSGQVQMRQGFFAVQQTCPHCQGRGTLIKDPCNKCHGHGRVERSKTLSVKIPA
                     GVDTGDRIRLAGEGEAGEHGAPAGDLYVQVQVKQHPIFEREGNNLYCEVPINFAMAAL
                     GGEIEVPTLDGRVKLKVPGETQTGKLFRMRGKGVKSVRGGAQGDLLCRVVVETPVGLN
                     ERQKQLLQELQESFGGPTGEHNSPRSKSFFDGVKKFFDDLTR"
     misc_feature    14168..15283
                     /gene="dnaJ"
                     /locus_tag="b0015"
                     /gene_synonym="ECK0015; faa; groP; grpC; JW0014"
                     /note="chaperone protein DnaJ; Provisional; Region:
                     PRK10767"
                     /db_xref="CDD:236757"
     misc_feature    14180..14344
                     /gene="dnaJ"
                     /locus_tag="b0015"
                     /gene_synonym="ECK0015; faa; groP; grpC; JW0014"
                     /note="DnaJ domain or J-domain.  DnaJ/Hsp40 (heat shock
                     protein 40) proteins are highly conserved and play crucial
                     roles in protein translation, folding, unfolding,
                     translocation, and degradation. They act primarily by
                     stimulating the ATPase activity of Hsp70s; Region: DnaJ;
                     cd06257"
                     /db_xref="CDD:99751"
     misc_feature    order(14264..14272,14297..14299,14306..14311,14318..14323)
                     /gene="dnaJ"
                     /locus_tag="b0015"
                     /gene_synonym="ECK0015; faa; groP; grpC; JW0014"
                     /note="HSP70 interaction site [polypeptide binding]; other
                     site"
                     /db_xref="CDD:99751"
     misc_feature    14510..15166
                     /gene="dnaJ"
                     /locus_tag="b0015"
                     /gene_synonym="ECK0015; faa; groP; grpC; JW0014"
                     /note="C-terminal substrate binding domain of DnaJ and
                     HSP40; Region: DnaJ_C; cd10747"
                     /db_xref="CDD:199909"
     misc_feature    order(14522..14524,14567..14584,14792..14794,14864..14866)
                     /gene="dnaJ"
                     /locus_tag="b0015"
                     /gene_synonym="ECK0015; faa; groP; grpC; JW0014"
                     /note="substrate binding site [polypeptide binding]; other
                     site"
                     /db_xref="CDD:199909"
     misc_feature    14597..14779
                     /gene="dnaJ"
                     /locus_tag="b0015"
                     /gene_synonym="ECK0015; faa; groP; grpC; JW0014"
                     /note="Zinc finger domain of DnaJ and HSP40; Region:
                     DnaJ_zf; cd10719"
                     /db_xref="CDD:199908"
     misc_feature    order(14597..14599,14606..14608,14648..14650,14657..14659,
                     14714..14716,14723..14725,14756..14758,14765..14767)
                     /gene="dnaJ"
                     /locus_tag="b0015"
                     /gene_synonym="ECK0015; faa; groP; grpC; JW0014"
                     /note="Zn binding sites [ion binding]; other site"
                     /db_xref="CDD:199908"
     misc_feature    order(14978..14983,14990..14995,15053..15064,15152..15166)
                     /gene="dnaJ"
                     /locus_tag="b0015"
                     /gene_synonym="ECK0015; faa; groP; grpC; JW0014"
                     /note="dimer interface [polypeptide binding]; other site"
                     /db_xref="CDD:199909"
     mobile_element  15387..16731
                     /mobile_element_type="insertion sequence:IS186A"
     gene            15445..16557
                     /gene="insL1"
                     /locus_tag="b0016"
                     /gene_synonym="ECK0016"
                     /db_xref="EcoGene:EG40012"
                     /db_xref="GeneID:944754"
     CDS             15445..16557
                     /gene="insL1"
                     /locus_tag="b0016"
                     /gene_synonym="ECK0016"
                     /function="IS, phage, Tn; Transposon-related functions;
                     extrachromosomal; transposon related"
                     /codon_start=1
                     /transl_table=11
                     /product="IS186 transposase"
                     /protein_id="NP_414557.1"
                     /db_xref="GI:16128010"
                     /db_xref="ASAP:ABE-0000058"
                     /db_xref="UniProtKB/Swiss-Prot:P0CF91"
                     /db_xref="EcoGene:EG40012"
                     /db_xref="GeneID:944754"
                     /translation="MNYSHDNWSAILAHIGKPEELDTSARNAGALTRRREIRDAATLL
                     RLGLAYGPGGMSLREVTAWAQLHDVATLSDVALLKRLRNAADWFGILAAQTLAVRAAV
                     TGCTSGKRLRLVDGTAISAPGGGSAEWRLHMGYDPHTCQFTDFELTDSRDAERLDRFA
                     QTADEIRIADRGFGSRPECIRSLAFGEADYIVRVHWRGLRWLTAEGMRFDMMGFLRGL
                     DCGKNGETTVMIGNSGNKKAGAPFPARLIAVSLPPEKALISKTRLLSENRRKGRVVQA
                     ETLEAAGHVLLLTSLPEDEYSAEQVADCYRLRWQIELAFKRLKSLLHLDALRAKEPEL
                     AKAWIFANLLAAFLIDDIIQPSLDFPPRSAGSEKKN"
     misc_feature    15526..16491
                     /gene="insL1"
                     /locus_tag="b0016"
                     /gene_synonym="ECK0016"
                     /note="FOG: Transposase and inactivated derivatives [DNA
                     replication, recombination, and repair]; Region: COG3385"
                     /db_xref="CDD:225920"
     misc_feature    15763..16488
                     /gene="insL1"
                     /locus_tag="b0016"
                     /gene_synonym="ECK0016"
                     /note="Transposase DDE domain; Region: DDE_Tnp_1;
                     pfam01609"
                     /db_xref="CDD:250742"
     gene            complement(16751..16960)
                     /gene="mokC"
                     /locus_tag="b0018"
                     /gene_synonym="ECK4466; gefL"
                     /db_xref="EcoGene:EG12074"
                     /db_xref="GeneID:944756"
     CDS             complement(16751..16960)
                     /gene="mokC"
                     /locus_tag="b0018"
                     /gene_synonym="ECK4466; gefL"
                     /note="regulatory peptide whose translation enables hokC
                     (gef) expression;
                     completely contained in another CDS"
                     /codon_start=1
                     /transl_table=11
                     /product="regulatory protein for HokC, overlaps CDS of
                     hokC"
                     /protein_id="NP_414559.1"
                     /db_xref="GI:16128012"
                     /db_xref="ASAP:ABE-0000064"
                     /db_xref="UniProtKB/Swiss-Prot:P33236"
                     /db_xref="EcoGene:EG12074"
                     /db_xref="GeneID:944756"
                     /translation="MLNTCRVPLTDRKVKEKRAMKQHKAMIVALIVICITAVVAALVT
                     RKDLCEVHIRTGQTEVAVFTAYESE"
     misc_feature    complement(16763..16891)
                     /gene="mokC"
                     /locus_tag="b0018"
                     /gene_synonym="ECK4466; gefL"
                     /note="Hok/gef family; Region: HOK_GEF; pfam01848"
                     /db_xref="CDD:202008"
     gene            complement(16751..16903)
                     /gene="hokC"
                     /locus_tag="b4412"
                     /gene_synonym="ECK0018; gef; JW5879"
                     /db_xref="EcoGene:EG10373"
                     /db_xref="GeneID:2847744"
     CDS             complement(16751..16903)
                     /gene="hokC"
                     /locus_tag="b4412"
                     /gene_synonym="ECK0018; gef; JW5879"
                     /note="small toxic membrane polypeptide;
                     completely contained in another CDS"
                     /codon_start=1
                     /transl_table=11
                     /product="toxic membrane protein, small"
                     /protein_id="YP_025292.1"
                     /db_xref="GI:49175991"
                     /db_xref="ASAP:ABE-0047278"
                     /db_xref="UniProtKB/Swiss-Prot:P0ACG4"
                     /db_xref="EcoGene:EG10373"
                     /db_xref="GeneID:2847744"
                     /translation="MKQHKAMIVALIVICITAVVAALVTRKDLCEVHIRTGQTEVAVF
                     TAYESE"
     misc_feature    complement(16763..16891)
                     /gene="hokC"
                     /locus_tag="b4412"
                     /gene_synonym="ECK0018; gef; JW5879"
                     /note="Hok/gef family; Region: HOK_GEF; pfam01848"
                     /db_xref="CDD:202008"
     gene            16952..17006
                     /gene="sokC"
                     /locus_tag="b4413"
                     /gene_synonym="ECK0019; JWR0224; sof"
                     /db_xref="EcoGene:EG31128"
                     /db_xref="GeneID:2847745"
     ncRNA           16952..17006
                     /gene="sokC"
                     /locus_tag="b4413"
                     /gene_synonym="ECK0019; JWR0224; sof"
                     /ncRNA_class="antisense_RNA"
                     /product="sRNA antisense regulator blocking mokC, and
                     hence hokC, translation"
                     /note="IS186A interrupts hokC transcript downstream of
                     hokC gene in K-12"
                     /function="component of addiction module"
                     /db_xref="ASAP:ABE-0047238"
                     /db_xref="EcoGene:EG31128"
                     /db_xref="GeneID:2847745"
     gene            17489..18655
                     /gene="nhaA"
                     /locus_tag="b0019"
                     /gene_synonym="ant; antA; ECK0020; JW0018"
                     /db_xref="EcoGene:EG10652"
                     /db_xref="GeneID:944758"
     CDS             17489..18655
                     /gene="nhaA"
                     /locus_tag="b0019"
                     /gene_synonym="ant; antA; ECK0020; JW0018"
                     /function="transport; Transport of small molecules:
                     Cations"
                     /experiment="N-terminus verified by Edman degradation:
                     PMID 8381959"
                     /GO_component="GO:0009274 - peptidoglycan-based cell wall"
                     /GO_component="GO:0019866 - organelle inner membrane"
                     /GO_process="GO:0009268 - response to pH"
                     /note="Na+/H antiporter, pH dependent"
                     /codon_start=1
                     /transl_table=11
                     /product="sodium-proton antiporter"
                     /protein_id="NP_414560.1"
                     /db_xref="GI:16128013"
                     /db_xref="ASAP:ABE-0000068"
                     /db_xref="UniProtKB/Swiss-Prot:P13738"
                     /db_xref="EcoGene:EG10652"
                     /db_xref="GeneID:944758"
                     /translation="MKHLHRFFSSDASGGIILIIAAILAMIMANSGATSGWYHDFLET
                     PVQLRVGSLEINKNMLLWINDALMAVFFLLVGLEVKRELMQGSLASLRQAAFPVIAAI
                     GGMIVPALLYLAFNYADPITREGWAIPAATDIAFALGVLALLGSRVPLALKIFLMALA
                     IIDDLGAIIIIALFYTNDLSMASLGVAAVAIAVLAVLNLCGARRTGVYILVGVVLWTA
                     VLKSGVHATLAGVIVGFFIPLKEKHGRSPAKRLEHVLHPWVAYLILPLFAFANAGVSL
                     QGVTLDGLTSILPLGIIAGLLIGKPLGISLFCWLALRLKLAHLPEGTTYQQIMVVGIL
                     CGIGFTMSIFIASLAFGSVDPELINWAKLGILVGSISSAVIGYSWLRVRLRPSV"
     misc_feature    17489..18652
                     /gene="nhaA"
                     /locus_tag="b0019"
                     /gene_synonym="ant; antA; ECK0020; JW0018"
                     /note="pH-dependent sodium/proton antiporter; Reviewed;
                     Region: nhaA; PRK09561"
                     /db_xref="CDD:181955"
     gene            18715..19620
                     /gene="nhaR"
                     /locus_tag="b0020"
                     /gene_synonym="antO; ECK0021; JW0019; yaaB"
                     /db_xref="EcoGene:EG11078"
                     /db_xref="GeneID:944757"
     CDS             18715..19620
                     /gene="nhaR"
                     /locus_tag="b0020"
                     /gene_synonym="antO; ECK0021; JW0019; yaaB"
                     /function="regulator; Transport of small molecules:
                     Cations"
                     /GO_component="GO:0005737 - cytoplasm"
                     /GO_function="GO:0016563 - transcription activator
                     activity"
                     /GO_process="GO:0006350 - transcription"
                     /GO_process="GO:0009268 - response to pH"
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional activator of nhaA"
                     /protein_id="NP_414561.1"
                     /db_xref="GI:16128014"
                     /db_xref="ASAP:ABE-0000072"
                     /db_xref="UniProtKB/Swiss-Prot:P0A9G2"
                     /db_xref="EcoGene:EG11078"
                     /db_xref="GeneID:944757"
                     /translation="MSMSHINYNHLYYFWHVYKEGSVVGAAEALYLTPQTITGQIRAL
                     EERLQGKLFKRKGRGLEPSELGELVYRYADKMFTLSQEMLDIVNYRKESNLLFDVGVA
                     DALSKRLVSSVLNAAVVEGEPIHLRCFESTHEMLLEQLSQHKLDMIISDCPIDSTQQE
                     GLFSVRIGECGVSFWCTNPPPEKPFPACLEERRLLIPGRRSMLGRKLLNWFNSQGLNV
                     EILGEFDDAALMKAFGAMHNAIFVAPTLYAYDFYADKTVVEIGRVENVMEEYHAIFAE
                     RMIQHPAVQRICNTDYSALFSPAVR"
     misc_feature    18721..19608
                     /gene="nhaR"
                     /locus_tag="b0020"
                     /gene_synonym="antO; ECK0021; JW0019; yaaB"
                     /note="transcriptional activator NhaR; Provisional;
                     Region: nhaR; PRK11062"
                     /db_xref="CDD:182938"
     misc_feature    18739..18915
                     /gene="nhaR"
                     /locus_tag="b0020"
                     /gene_synonym="antO; ECK0021; JW0019; yaaB"
                     /note="Bacterial regulatory helix-turn-helix protein, lysR
                     family; Region: HTH_1; pfam00126"
                     /db_xref="CDD:249610"
     misc_feature    19000..19602
                     /gene="nhaR"
                     /locus_tag="b0020"
                     /gene_synonym="antO; ECK0021; JW0019; yaaB"
                     /note="The C-terminal substrate binding domain of
                     LysR-type transcriptional activator of the nhaA gene,
                     encoding Na+/H+ antiporter, contains the type 2
                     periplasmic binding fold; Region: PBP2_NhaR; cd08429"
                     /db_xref="CDD:176120"
     misc_feature    order(19045..19050,19054..19059,19066..19068,19078..19080,
                     19084..19104,19375..19392,19408..19413,19417..19422)
                     /gene="nhaR"
                     /locus_tag="b0020"
                     /gene_synonym="antO; ECK0021; JW0019; yaaB"
                     /note="putative dimerization interface [polypeptide
                     binding]; other site"
                     /db_xref="CDD:176120"
     mobile_element  complement(19796..20563)
                     /mobile_element_type="insertion sequence:IS1A"
     gene            complement(19811..20314)
                     /gene="insB1"
                     /locus_tag="b0021"
                     /gene_synonym="ECK0022"
                     /db_xref="EcoGene:EG40002"
                     /db_xref="GeneID:944743"
     CDS             complement(19811..20314)
                     /gene="insB1"
                     /locus_tag="b0021"
                     /gene_synonym="ECK0022"
                     /function="IS, phage, Tn; Transposon-related functions;
                     extrachromosomal; transposon related"
                     /codon_start=1
                     /transl_table=11
                     /product="IS1 transposase B"
                     /protein_id="NP_414562.1"
                     /db_xref="GI:16128015"
                     /db_xref="ASAP:ABE-0000075"
                     /db_xref="UniProtKB/Swiss-Prot:P0CF25"
                     /db_xref="EcoGene:EG40002"
                     /db_xref="GeneID:944743"
                     /translation="MPGNSPHYGRWPQHDFTSLKKLRPQSVTSRIQPGSDVIVCAEMD
                     EQWGYVGAKSRQRWLFYAYDSLRKTVVAHVFGERTMATLGRLMSLLSPFDVVIWMTDG
                     WPLYESRLKGKLHVISKRYTQRIERHNLNLRQHLARLGRKSLSFSKSVELHDKVIGHY
                     LNIKHYQ"
     misc_feature    complement(19814..20203)
                     /gene="insB1"
                     /locus_tag="b0021"
                     /gene_synonym="ECK0022"
                     /note="IS1 transposase; Region: DDE_Tnp_IS1; pfam03400"
                     /db_xref="CDD:112225"
     gene            complement(20233..20508)
                     /gene="insA"
                     /locus_tag="b0022"
                     /gene_synonym="ECK0023"
                     /note="insA1"
                     /db_xref="EcoGene:EG40001"
                     /db_xref="GeneID:948449"
     CDS             complement(20233..20508)
                     /gene="insA"
                     /locus_tag="b0022"
                     /gene_synonym="ECK0023"
                     /function="IS, phage, Tn; Transposon-related functions;
                     extrachromosomal; transposon related"
                     /codon_start=1
                     /transl_table=11
                     /product="IS1 repressor TnpA"
                     /protein_id="NP_414563.1"
                     /db_xref="GI:16128016"
                     /db_xref="ASAP:ABE-0000078"
                     /db_xref="UniProtKB/Swiss-Prot:P0CF07"
                     /db_xref="EcoGene:EG40001"
                     /db_xref="GeneID:948449"
                     /translation="MASVSISCPSCSATDGVVRNGKSTAGHQRYLCSHCRKTWQLQFT
                     YTASQPGTHQKIIDMAMNGVGCRATARIMGVGLNTILRHLKNSGRSR"
     misc_feature    complement(20236..20508)
                     /gene="insA"
                     /locus_tag="b0022"
                     /gene_synonym="ECK0023"
                     /note="Transposase and inactivated derivatives [DNA
                     replication, recombination, and repair]; Region: COG3677"
                     /db_xref="CDD:226202"
     misc_feature    complement(20401..20508)
                     /gene="insA"
                     /locus_tag="b0022"
                     /gene_synonym="ECK0023"
                     /note="InsA N-terminal domain; Region: Zn_Tnp_IS1;
                     pfam03811"
                     /db_xref="CDD:190760"
     misc_feature    complement(20245..20382)
                     /gene="insA"
                     /locus_tag="b0022"
                     /gene_synonym="ECK0023"
                     /note="InsA C-terminal domain; Region: HTH_Tnp_IS1;
                     pfam12759"
                     /db_xref="CDD:257276"
     gene            complement(20815..21078)
                     /gene="rpsT"
                     /locus_tag="b0023"
                     /gene_synonym="ECK0024; JW0022; sup"
                     /db_xref="EcoGene:EG10919"
                     /db_xref="GeneID:944759"
     CDS             complement(20815..21078)
                     /gene="rpsT"
                     /locus_tag="b0023"
                     /gene_synonym="ECK0024; JW0022; sup"
                     /function="structural component; Ribosomal proteins -
                     synthesis, modification"
                     /GO_component="GO:0005737 - cytoplasm"
                     /GO_function="GO:0003735 - structural constituent of
                     ribosome"
                     /GO_process="GO:0006412 - translation"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal subunit protein S20"
                     /protein_id="NP_414564.1"
                     /db_xref="GI:16128017"
                     /db_xref="ASAP:ABE-0000082"
                     /db_xref="UniProtKB/Swiss-Prot:P0A7U7"
                     /db_xref="EcoGene:EG10919"
                     /db_xref="GeneID:944759"
                     /translation="MANIKSAKKRAIQSEKARKHNASRRSMMRTFIKKVYAAIEAGDK
                     AAAQKAFNEMQPIVDRQAAKGLIHKNKAARHKANLTAQINKLA"
     misc_feature    complement(20818..21078)
                     /gene="rpsT"
                     /locus_tag="b0023"
                     /gene_synonym="ECK0024; JW0022; sup"
                     /note="30S ribosomal protein S20; Reviewed; Region: rpsT;
                     PRK00239"
                     /db_xref="CDD:178943"
     gene            21181..21399
                     /gene="yaaY"
                     /locus_tag="b0024"
                     /gene_synonym="ECK0025; JW5003"
                     /db_xref="EcoGene:EG14386"
                     /db_xref="GeneID:949128"
     CDS             21181..21399
                     /gene="yaaY"
                     /locus_tag="b0024"
                     /gene_synonym="ECK0025; JW5003"
                     /codon_start=1
                     /transl_table=11
                     /product="uncharacterized protein"
                     /protein_id="NP_414565.1"
                     /db_xref="GI:16128018"
                     /db_xref="ASAP:ABE-0000089"
                     /db_xref="UniProtKB/Swiss-Prot:P75620"
                     /db_xref="EcoGene:EG14386"
                     /db_xref="GeneID:949128"
                     /translation="MCRHSLRSDGAGFYQLAGCEYSFSAIKIAAGGQFLPVICAMAMK
                     SHFFLISVLNRRLTLTAVQGILGRFSLF"
     misc_feature    21184..21396
                     /gene="yaaY"
                     /locus_tag="b0024"
                     /gene_synonym="ECK0025; JW5003"
                     /note="Protein of unknown function (DUF2575); Region:
                     DUF2575; pfam10837"
                     /db_xref="CDD:151286"
     gene            21407..22348
                     /gene="ribF"
                     /locus_tag="b0025"
                     /gene_synonym="ECK0026; JW0023; yaaC"
                     /db_xref="EcoGene:EG11079"
                     /db_xref="GeneID:949129"
     CDS             21407..22348
                     /gene="ribF"
                     /locus_tag="b0025"
                     /gene_synonym="ECK0026; JW0023; yaaC"
                     /EC_number="2.7.1.26"
                     /EC_number="2.7.7.2"
                     /function="putative regulator; Not classified"
                     /GO_component="GO:0005737 - cytoplasm"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional riboflavin kinase/FAD synthetase"
                     /protein_id="NP_414566.1"
                     /db_xref="GI:16128019"
                     /db_xref="ASAP:ABE-0000091"
                     /db_xref="UniProtKB/Swiss-Prot:P0AG40"
                     /db_xref="EcoGene:EG11079"
                     /db_xref="GeneID:949129"
                     /translation="MKLIRGIHNLSQAPQEGCVLTIGNFDGVHRGHRALLQGLQEEGR
                     KRNLPVMVMLFEPQPLELFATDKAPARLTRLREKLRYLAECGVDYVLCVRFDRRFAAL
                     TAQNFISDLLVKHLRVKFLAVGDDFRFGAGREGDFLLLQKAGMEYGFDITSTQTFCEG
                     GVRISSTAVRQALADDNLALAESLLGHPFAISGRVVHGDELGRTIGFPTANVPLRRQV
                     SPVKGVYAVEVLGLGEKPLPGVANIGTRPTVAGIRQQLEVHLLDVAMDLYGRHIQVVL
                     RKKIRNEQRFASLDELKAQIARDELTAREFFGLTKPA"
     misc_feature    21410..22333
                     /gene="ribF"
                     /locus_tag="b0025"
                     /gene_synonym="ECK0026; JW0023; yaaC"
                     /note="bifunctional riboflavin kinase/FMN
                     adenylyltransferase; Reviewed; Region: PRK05627"
                     /db_xref="CDD:235536"
     misc_feature    21458..22000
                     /gene="ribF"
                     /locus_tag="b0025"
                     /gene_synonym="ECK0026; JW0023; yaaC"
                     /note="FAD synthetase, N-terminal domain of the
                     bifunctional enzyme; Region: FAD_synthetase_N; cd02064"
                     /db_xref="CDD:185679"
     misc_feature    order(21473..21484,21491..21493,21500..21502,21782..21784,
                     21872..21874,21896..21904)
                     /gene="ribF"
                     /locus_tag="b0025"
                     /gene_synonym="ECK0026; JW0023; yaaC"
                     /note="active site"
                     /db_xref="CDD:185679"
     misc_feature    21956..22327
                     /gene="ribF"
                     /locus_tag="b0025"
                     /gene_synonym="ECK0026; JW0023; yaaC"
                     /note="Riboflavin kinase; Region: Flavokinase; smart00904"
                     /db_xref="CDD:214901"
     gene            22391..25207
                     /gene="ileS"
                     /locus_tag="b0026"
                     /gene_synonym="ECK0027; ilvS; JW0024"
                     /db_xref="EcoGene:EG10492"
                     /db_xref="GeneID:944761"
     CDS             22391..25207
                     /gene="ileS"
                     /locus_tag="b0026"
                     /gene_synonym="ECK0027; ilvS; JW0024"
                     /EC_number="6.1.1.5"
                     /function="enzyme; Aminoacyl tRNA synthetases, tRNA
                     modification"
                     /GO_component="GO:0005737 - cytoplasm"
                     /GO_process="GO:0006418 - tRNA aminoacylation for protein
                     translation"
                     /note="isoleucine tRNA synthetase"
                     /codon_start=1
                     /transl_table=11
                     /product="isoleucyl-tRNA synthetase"
                     /protein_id="NP_414567.1"
                     /db_xref="GI:16128020"
                     /db_xref="ASAP:ABE-0000094"
                     /db_xref="UniProtKB/Swiss-Prot:P00956"
                     /db_xref="EcoGene:EG10492"
                     /db_xref="GeneID:944761"
                     /translation="MSDYKSTLNLPETGFPMRGDLAKREPGMLARWTDDDLYGIIRAA
                     KKGKKTFILHDGPPYANGSIHIGHSVNKILKDIIVKSKGLSGYDSPYVPGWDCHGLPI
                     ELKVEQEYGKPGEKFTAAEFRAKCREYAATQVDGQRKDFIRLGVLGDWSHPYLTMDFK
                     TEANIIRALGKIIGNGHLHKGAKPVHWCVDCRSALAEAEVEYYDKTSPSIDVAFQAVD
                     QDALKAKFAVSNVNGPISLVIWTTTPWTLPANRAISIAPDFDYALVQIDGQAVILAKD
                     LVESVMQRIGVTDYTILGTVKGAELELLRFTHPFMGFDVPAILGDHVTLDAGTGAVHT
                     APGHGPDDYVIGQKYGLETANPVGPDGTYLPGTYPTLDGVNVFKANDIVVALLQEKGA
                     LLHVEKMQHSYPCCWRHKTPIIFRATPQWFVSMDQKGLRAQSLKEIKGVQWIPDWGQA
                     RIESMVANRPDWCISRQRTWGVPMSLFVHKDTEELHPRTLELMEEVAKRVEVDGIQAW
                     WDLDAKEILGDEADQYVKVPDTLDVWFDSGSTHSSVVDVRPEFAGHAADMYLEGSDQH
                     RGWFMSSLMISTAMKGKAPYRQVLTHGFTVDGQGRKMSKSIGNTVSPQDVMNKLGADI
                     LRLWVASTDYTGEMAVSDEILKRAADSYRRIRNTARFLLANLNGFDPAKDMVKPEEMV
                     VLDRWAVGCAKAAQEDILKAYEAYDFHEVVQRLMRFCSVEMGSFYLDIIKDRQYTAKA
                     DSVARRSCQTALYHIAEALVRWMAPILSFTADEVWGYLPGEREKYVFTGEWYEGLFGL
                     ADSEAMNDAFWDELLKVRGEVNKVIEQARADKKVGGSLEAAVTLYAEPELSAKLTALG
                     DELRFVLLTSGATVADYNDAPADAQQSEVLKGLKVALSKAEGEKCPRCWHYTQDVGKV
                     AEHAEICGRCVSNVAGDGEKRKFA"
     misc_feature    22391..25180
                     /gene="ileS"
                     /locus_tag="b0026"
                     /gene_synonym="ECK0027; ilvS; JW0024"
                     /note="isoleucyl-tRNA synthetase; Reviewed; Region: ileS;
                     PRK05743"
                     /db_xref="CDD:235588"
     misc_feature    22535..24310
                     /gene="ileS"
                     /locus_tag="b0026"
                     /gene_synonym="ECK0027; ilvS; JW0024"
                     /note="catalytic core domain of isoleucyl-tRNA
                     synthetases; Region: IleRS_core; cd00818"
                     /db_xref="CDD:173909"
     misc_feature    order(22559..22567,22583..22585,22589..22594,22601..22603,
                     23741..23743,23990..23992,23999..24001,24071..24085,
                     24089..24091,24095..24097,24164..24178,24188..24205,
                     24299..24301)
                     /gene="ileS"
                     /locus_tag="b0026"
                     /gene_synonym="ECK0027; ilvS; JW0024"
                     /note="active site"
                     /db_xref="CDD:173909"
     misc_feature    22583..22594
                     /gene="ileS"
                     /locus_tag="b0026"
                     /gene_synonym="ECK0027; ilvS; JW0024"
                     /note="HIGH motif; other site"
                     /db_xref="CDD:173909"
     misc_feature    24194..24208
                     /gene="ileS"
                     /locus_tag="b0026"
                     /gene_synonym="ECK0027; ilvS; JW0024"
                     /note="KMSKS motif; other site"
                     /db_xref="CDD:173909"
     misc_feature    24308..24850
                     /gene="ileS"
                     /locus_tag="b0026"
                     /gene_synonym="ECK0027; ilvS; JW0024"
                     /note="Anticodon-binding domain of bacterial and
                     eukaryotic mitochondrial isoleucyl tRNA synthetases;
                     Region: Anticodon_Ia_Ile_BEm; cd07960"
                     /db_xref="CDD:153414"
     misc_feature    order(24317..24319,24329..24331,24338..24340,24350..24352,
                     24359..24361,24368..24373,24515..24517,24524..24529,
                     24536..24541,24548..24550,24563..24565,24575..24577,
                     24584..24586,24839..24841,24848..24850)
                     /gene="ileS"
                     /locus_tag="b0026"
                     /gene_synonym="ECK0027; ilvS; JW0024"
                     /note="tRNA binding surface [nucleotide binding]; other
                     site"
                     /db_xref="CDD:153414"
     misc_feature    order(24359..24361,24368..24370)
                     /gene="ileS"
                     /locus_tag="b0026"
                     /gene_synonym="ECK0027; ilvS; JW0024"
                     /note="anticodon binding site; other site"
                     /db_xref="CDD:153414"
     misc_feature    25082..25171
                     /gene="ileS"
                     /locus_tag="b0026"
                     /gene_synonym="ECK0027; ilvS; JW0024"
                     /note="Zinc finger found in FPG and IleRS; Region:
                     zf-FPG_IleRS; pfam06827"
                     /db_xref="CDD:253933"
     gene            25207..25701
                     /gene="lspA"
                     /locus_tag="b0027"
                     /gene_synonym="ECK0028; JW0025"
                     /db_xref="EcoGene:EG10548"
                     /db_xref="GeneID:944800"
     CDS             25207..25701
                     /gene="lspA"
                     /locus_tag="b0027"
                     /gene_synonym="ECK0028; JW0025"
                     /EC_number="3.4.23.36"
                     /function="enzyme; Protein, peptide secretion"
                     /GO_component="GO:0009274 - peptidoglycan-based cell wall"
                     /GO_component="GO:0019866 - organelle inner membrane"
                     /note="prolipoprotein signal peptidase (SPase II)"
                     /codon_start=1
                     /transl_table=11
                     /product="prolipoprotein signal peptidase (signal
                     peptidase II)"
                     /protein_id="NP_414568.1"
                     /db_xref="GI:16128021"
                     /db_xref="ASAP:ABE-0000096"
                     /db_xref="UniProtKB/Swiss-Prot:P00804"
                     /db_xref="EcoGene:EG10548"
                     /db_xref="GeneID:944800"
                     /translation="MSQSICSTGLRWLWLVVVVLIIDLGSKYLILQNFALGDTVPLFP
                     SLNLHYARNYGAAFSFLADSGGWQRWFFAGIAIGISVILAVMMYRSKATQKLNNIAYA
                     LIIGGALGNLFDRLWHGFVVDMIDFYVGDWHFATFNLADTAICVGAALIVLEGFLPSR
                     AKKQ"
     misc_feature    25210..25686
                     /gene="lspA"
                     /locus_tag="b0027"
                     /gene_synonym="ECK0028; JW0025"
                     /note="lipoprotein signal peptidase; Reviewed; Region:
                     lspA; PRK00376"
                     /db_xref="CDD:234739"
     repeat_region   25710..25795
                     /note="REP2 (repetitive extragenic palindromic) element;
                     contains 2 REP sequences"
     gene            25826..26275
                     /gene="fkpB"
                     /locus_tag="b0028"
                     /gene_synonym="ECK0029; JW0026; slpA; yaaD"
                     /db_xref="EcoGene:EG11080"
                     /db_xref="GeneID:944807"
     CDS             25826..26275
                     /gene="fkpB"
                     /locus_tag="b0028"
                     /gene_synonym="ECK0029; JW0026; slpA; yaaD"
                     /EC_number="5.2.1.8"
                     /function="putative enzyme; Proteins - translation and
                     modification"
                     /GO_component="GO:0005737 - cytoplasm"
                     /GO_process="GO:0006457 - protein folding"
                     /codon_start=1
                     /transl_table=11
                     /product="FKBP-type peptidyl-prolyl cis-trans isomerase
                     (rotamase)"
                     /protein_id="NP_414569.1"
                     /db_xref="GI:16128022"
                     /db_xref="ASAP:ABE-0000101"
                     /db_xref="UniProtKB/Swiss-Prot:P0AEM0"
                     /db_xref="EcoGene:EG11080"
                     /db_xref="GeneID:944807"
                     /translation="MSESVQSNSAVLVHFTLKLDDGTTAESTRNNGKPALFRLGDASL
                     SEGLEQHLLGLKVGDKTTFSLEPDAAFGVPSPDLIQYFSRREFMDAGEPEIGAIMLFT
                     AMDGSEMPGVIREINGDSITVDFNHPLAGQTVHFDIEVLEIDPALEA"
     misc_feature    25826..26272
                     /gene="fkpB"
                     /locus_tag="b0028"
                     /gene_synonym="ECK0029; JW0026; slpA; yaaD"
                     /note="FKBP-type peptidyl-prolyl cis-trans isomerase;
                     Provisional; Region: PRK15095"
                     /db_xref="CDD:237908"
     misc_feature    25838..26269
                     /gene="fkpB"
                     /locus_tag="b0028"
                     /gene_synonym="ECK0029; JW0026; slpA; yaaD"
                     /note="FKBP-type peptidyl-prolyl cis-trans isomerases 2
                     [Posttranslational modification, protein turnover,
                     chaperones]; Region: SlpA; COG1047"
                     /db_xref="CDD:223976"
     gene            26277..27227
                     /gene="ispH"
                     /locus_tag="b0029"
                     /gene_synonym="ECK0030; JW0027; lytB; yaaE"
                     /db_xref="EcoGene:EG11081"
                     /db_xref="GeneID:944777"
     CDS             26277..27227
                     /gene="ispH"
                     /locus_tag="b0029"
                     /gene_synonym="ECK0030; JW0027; lytB; yaaE"
                     /EC_number="1.17.1.2"
                     /GO_component="GO:0005737 - cytoplasm"
                     /GO_process="GO:0042493 - response to drug"
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxy-3-methylbut-2-enyl diphosphate
                     reductase, 4Fe-4S protein"
                     /protein_id="NP_414570.1"
                     /db_xref="GI:16128023"
                     /db_xref="ASAP:ABE-0000103"
                     /db_xref="UniProtKB/Swiss-Prot:P62623"
                     /db_xref="EcoGene:EG11081"
                     /db_xref="GeneID:944777"
                     /translation="MQILLANPRGFCAGVDRAISIVENALAIYGAPIYVRHEVVHNRY
                     VVDSLRERGAIFIEQISEVPDGAILIFSAHGVSQAVRNEAKSRDLTVFDATCPLVTKV
                     HMEVARASRRGEESILIGHAGHPEVEGTMGQYSNPEGGMYLVESPDDVWKLTVKNEEK
                     LSFMTQTTLSVDDTSDVIDALRKRFPKIVGPRKDDICYATTNRQEAVRALAEQAEVVL
                     VVGSKNSSNSNRLAELAQRMGKRAFLIDDAKDIQEEWVKEVKCVGVTAGASAPDILVQ
                     NVVARLQQLGGGEAIPLEGREENIVFEVPKELRVDIREVD"
     misc_feature    26283..27122
                     /gene="ispH"
                     /locus_tag="b0029"
                     /gene_synonym="ECK0030; JW0027; lytB; yaaE"
                     /note="4-hydroxy-3-methylbut-2-enyl diphosphate reductase;
                     Region: lytB_ispH; cd13944"
                     /db_xref="CDD:260116"
     misc_feature    order(26310..26312,26562..26564,26865..26867)
                     /gene="ispH"
                     /locus_tag="b0029"
                     /gene_synonym="ECK0030; JW0027; lytB; yaaE"
                     /note="Fe-S cluster binding site [ion binding]; other
                     site"
                     /db_xref="CDD:260116"
     misc_feature    order(26319..26321,26394..26399,26493..26498,26646..26648,
                     26652..26654,26775..26780,26946..26957,27081..27083)
                     /gene="ispH"
                     /locus_tag="b0029"
                     /gene_synonym="ECK0030; JW0027; lytB; yaaE"
                     /note="substrate binding site [chemical binding]; other
                     site"
                     /db_xref="CDD:260116"
     misc_feature    order(26646..26648,26652..26654,26949..26951,26955..26957)
                     /gene="ispH"
                     /locus_tag="b0029"
                     /gene_synonym="ECK0030; JW0027; lytB; yaaE"
                     /note="catalytic site [active]"
                     /db_xref="CDD:260116"
     gene            27293..28207
                     /gene="rihC"
                     /locus_tag="b0030"
                     /gene_synonym="ECK0031; JW0028; yaaF"
                     /db_xref="EcoGene:EG11082"
                     /db_xref="GeneID:944796"
     CDS             27293..28207
                     /gene="rihC"
                     /locus_tag="b0030"
                     /gene_synonym="ECK0031; JW0028; yaaF"
                     /EC_number="3.2.2.-"
                     /GO_process="GO:0009226 - nucleotide-sugar biosynthetic
                     process"
                     /codon_start=1
                     /transl_table=11
                     /product="ribonucleoside hydrolase 3"
                     /protein_id="NP_414571.1"
                     /db_xref="GI:16128024"
                     /db_xref="ASAP:ABE-0000109"
                     /db_xref="UniProtKB/Swiss-Prot:P22564"
                     /db_xref="EcoGene:EG11082"
                     /db_xref="GeneID:944796"
                     /translation="MRLPIFLDTDPGIDDAVAIAAAIFAPELDLQLMTTVAGNVSVEK
                     TTRNALQLLHFWNAEIPLAQGAAVPLVRAPRDAASVHGESGMAGYDFVEHNRKPLGIP
                     AFLAIRDALMRAPEPVTLVAIGPLTNIALLLSQCPECKPYIRRLVIMGGSAGRGNCTP
                     NAEFNIAADPEAAACVFRSGIEIVMCGLDVTNQAILTPDYLSTLPQLNRTGKMLHALF
                     SHYRSGSMQSGLRMHDLCAIAWLVRPDLFTLKPCFVAVETQGEFTSGTTVVDIDGCLG
                     KPANVQVALDLDVKGFQQWVAEVLALAS"
     misc_feature    27302..28192
                     /gene="rihC"
                     /locus_tag="b0030"
                     /gene_synonym="ECK0031; JW0028; yaaF"
                     /note="nuc_hydro_IU_UC_XIUA: inosine-uridine preferring,
                     xanthosine-inosine-uridine-adenosine-preferring and,
                     uridine-cytidine preferring nucleoside hydrolases.
                     Nucleoside hydrolases cleave the N-glycosidic bond in
                     nucleosides generating ribose and the...; Region:
                     nuc_hydro_IU_UC_XIUA; cd02651"
                     /db_xref="CDD:239117"
     misc_feature    order(27320..27322,27332..27337,27407..27409,27530..27532,
                     27659..27661,27761..27763,27779..27781,27785..27787,
                     27992..27994)
                     /gene="rihC"
                     /locus_tag="b0030"
                     /gene_synonym="ECK0031; JW0028; yaaF"
                     /note="active site"
                     /db_xref="CDD:239117"
     misc_feature    order(27500..27502,27692..27694,27815..27817,28061..28063,
                     28067..28072,28079..28081)
                     /gene="rihC"
                     /locus_tag="b0030"
                     /gene_synonym="ECK0031; JW0028; yaaF"
                     /note="tetramer interface [polypeptide binding]; other
                     site"
                     /db_xref="CDD:239117"
     gene            28374..29195
                     /gene="dapB"
                     /locus_tag="b0031"
                     /gene_synonym="ECK0032; JW0029"
                     /db_xref="EcoGene:EG10206"
                     /db_xref="GeneID:944762"
     CDS             28374..29195
                     /gene="dapB"
                     /locus_tag="b0031"
                     /gene_synonym="ECK0032; JW0029"
                     /EC_number="1.17.1.8"
                     /function="enzyme; Amino acid biosynthesis: Lysine"
                     /GO_component="GO:0009274 - peptidoglycan-based cell wall"
                     /GO_component="GO:0005737 - cytoplasm"
                     /GO_process="GO:0009089 - lysine biosynthetic process via
                     diaminopimelate"
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrodipicolinate reductase"
                     /protein_id="NP_414572.1"
                     /db_xref="GI:16128025"
                     /db_xref="ASAP:ABE-0000112"
                     /db_xref="UniProtKB/Swiss-Prot:P04036"
                     /db_xref="EcoGene:EG10206"
                     /db_xref="GeneID:944762"
                     /translation="MHDANIRVAIAGAGGRMGRQLIQAALALEGVQLGAALEREGSSL
                     LGSDAGELAGAGKTGVTVQSSLDAVKDDFDVFIDFTRPEGTLNHLAFCRQHGKGMVIG
                     TTGFDEAGKQAIRDAAADIAIVFAANFSVGVNVMLKLLEKAAKVMGDYTDIEIIEAHH
                     RHKVDAPSGTALAMGEAIAHALDKDLKDCAVYSREGHTGERVPGTIGFATVRAGDIVG
                     EHTAMFADIGERLEITHKASSRMTFANGAVRSALWLSGKESGLFDMRDVLDLNNL"
     misc_feature    28389..29183
                     /gene="dapB"
                     /locus_tag="b0031"
                     /gene_synonym="ECK0032; JW0029"
                     /note="Dihydrodipicolinate reductase [Amino acid transport
                     and metabolism]; Region: DapB; COG0289"
                     /db_xref="CDD:223366"
     misc_feature    28389..28760
                     /gene="dapB"
                     /locus_tag="b0031"
                     /gene_synonym="ECK0032; JW0029"
                     /note="Dihydrodipicolinate reductase, N-terminus; Region:
                     DapB_N; pfam01113"
                     /db_xref="CDD:250369"
     misc_feature    28767..29177
                     /gene="dapB"
                     /locus_tag="b0031"
                     /gene_synonym="ECK0032; JW0029"
                     /note="Dihydrodipicolinate reductase, C-terminus; Region:
                     DapB_C; pfam05173"
                     /db_xref="CDD:253059"
     gene            29651..30799
                     /gene="carA"
                     /locus_tag="b0032"
                     /gene_synonym="arg; cap; ECK0033; JW0030; pyrA"
                     /db_xref="EcoGene:EG10134"
                     /db_xref="GeneID:949025"
     CDS             29651..30799
                     /gene="carA"
                     /locus_tag="b0032"
                     /gene_synonym="arg; cap; ECK0033; JW0030; pyrA"
                     /EC_number="6.3.5.5"
                     /function="enzyme; Pyrimidine ribonucleotide biosynthesis"
                     /experiment="N-terminus verified by Edman degradation:
                     PMID 3894020,9298646,9740056"
                     /GO_process="GO:0006526 - arginine biosynthetic process"
                     /GO_process="GO:0006221 - pyrimidine nucleotide
                     biosynthetic process"
                     /codon_start=1
                     /transl_table=11
                     /product="carbamoyl phosphate synthetase small subunit,
                     glutamine amidotransferase"
                     /protein_id="NP_414573.1"
                     /db_xref="GI:16128026"
                     /db_xref="ASAP:ABE-0000118"
                     /db_xref="UniProtKB/Swiss-Prot:P0A6F1"
                     /db_xref="EcoGene:EG10134"
                     /db_xref="GeneID:949025"
                     /translation="MIKSALLVLEDGTQFHGRAIGATGSAVGEVVFNTSMTGYQEILT
                     DPSYSRQIVTLTYPHIGNVGTNDADEESSQVHAQGLVIRDLPLIASNFRNTEDLSSYL
                     KRHNIVAIADIDTRKLTRLLREKGAQNGCIIAGDNPDAALALEKARAFPGLNGMDLAK
                     EVTTAEAYSWTQGSWTLTGGLPEAKKEDELPFHVVAYDFGAKRNILRMLVDRGCRLTI
                     VPAQTSAEDVLKMNPDGIFLSNGPGDPAPCDYAITAIQKFLETDIPVFGICLGHQLLA
                     LASGAKTVKMKFGHHGGNHPVKDVEKNVVMITAQNHGFAVDEATLPANLRVTHKSLFD
                     GTLQGIHRTDKPAFSFQGHPEASPGPHDAAPLFDHFIELIEQYRKTAK"
     misc_feature    29651..30772
                     /gene="carA"
                     /locus_tag="b0032"
                     /gene_synonym="arg; cap; ECK0033; JW0030; pyrA"
                     /note="carbamoyl phosphate synthase small subunit;
                     Reviewed; Region: PRK12564"
                     /db_xref="CDD:237139"
     misc_feature    29657..30046
                     /gene="carA"
                     /locus_tag="b0032"
                     /gene_synonym="arg; cap; ECK0033; JW0030; pyrA"
                     /note="Carbamoyl-phosphate synthase small chain, CPSase
                     domain; Region: CPSase_sm_chain; smart01097"
                     /db_xref="CDD:198165"
     misc_feature    30230..30763
                     /gene="carA"
                     /locus_tag="b0032"
                     /gene_synonym="arg; cap; ECK0033; JW0030; pyrA"
                     /note="Small chain of the glutamine-dependent form of
                     carbamoyl phosphate synthase, CPSase II; Region:
                     GATase1_CPSase; cd01744"
                     /db_xref="CDD:153215"
     misc_feature    order(30455..30457,30707..30709,30713..30715)
                     /gene="carA"
                     /locus_tag="b0032"
                     /gene_synonym="arg; cap; ECK0033; JW0030; pyrA"
                     /note="catalytic site [active]"
                     /db_xref="CDD:153215"
     misc_feature    order(30530..30532,30536..30538,30557..30559,30563..30565,
                     30644..30646,30722..30727,30731..30736)
                     /gene="carA"
                     /locus_tag="b0032"
                     /gene_synonym="arg; cap; ECK0033; JW0030; pyrA"
                     /note="subunit interface [polypeptide binding]; other
                     site"
                     /db_xref="CDD:153215"
     gene            30817..34038
                     /gene="carB"
                     /locus_tag="b0033"
                     /gene_synonym="cap; ECK0034; JW0031; pyrA"
                     /db_xref="EcoGene:EG10135"
                     /db_xref="GeneID:944775"
     CDS             30817..34038
                     /gene="carB"
                     /locus_tag="b0033"
                     /gene_synonym="cap; ECK0034; JW0031; pyrA"
                     /EC_number="6.3.5.5"
                     /function="enzyme; Pyrimidine ribonucleotide biosynthesis"
                     /GO_process="GO:0006526 - arginine biosynthetic process"
                     /GO_process="GO:0006221 - pyrimidine nucleotide
                     biosynthetic process"
                     /codon_start=1
                     /transl_table=11
                     /product="carbamoyl-phosphate synthase large subunit"
                     /protein_id="NP_414574.1"
                     /db_xref="GI:16128027"
                     /db_xref="ASAP:ABE-0000121"
                     /db_xref="UniProtKB/Swiss-Prot:P00968"
                     /db_xref="EcoGene:EG10135"
                     /db_xref="GeneID:944775"
                     /translation="MPKRTDIKSILILGAGPIVIGQACEFDYSGAQACKALREEGYRV
                     ILVNSNPATIMTDPEMADATYIEPIHWEVVRKIIEKERPDAVLPTMGGQTALNCALEL
                     ERQGVLEEFGVTMIGATADAIDKAEDRRRFDVAMKKIGLETARSGIAHTMEEALAVAA
                     DVGFPCIIRPSFTMGGSGGGIAYNREEFEEICARGLDLSPTKELLIDESLIGWKEYEM
                     EVVRDKNDNCIIVCSIENFDAMGIHTGDSITVAPAQTLTDKEYQIMRNASMAVLREIG
                     VETGGSNVQFAVNPKNGRLIVIEMNPRVSRSSALASKATGFPIAKVAAKLAVGYTLDE
                     LMNDITGGRTPASFEPSIDYVVTKIPRFNFEKFAGANDRLTTQMKSVGEVMAIGRTQQ
                     ESLQKALRGLEVGATGFDPKVSLDDPEALTKIRRELKDAGADRIWYIADAFRAGLSVD
                     GVFNLTNIDRWFLVQIEELVRLEEKVAEVGITGLNADFLRQLKRKGFADARLAKLAGV
                     REAEIRKLRDQYDLHPVYKRVDTCAAEFATDTAYMYSTYEEECEANPSTDREKIMVLG
                     GGPNRIGQGIEFDYCCVHASLALREDGYETIMVNCNPETVSTDYDTSDRLYFEPVTLE
                     DVLEIVRIEKPKGVIVQYGGQTPLKLARALEAAGVPVIGTSPDAIDRAEDRERFQHAV
                     ERLKLKQPANATVTAIEMAVEKAKEIGYPLVVRPSYVLGGRAMEIVYDEADLRRYFQT
                     AVSVSNDAPVLLDHFLDDAVEVDVDAICDGEMVLIGGIMEHIEQAGVHSGDSACSLPA
                     YTLSQEIQDVMRQQVQKLAFELQVRGLMNVQFAVKNNEVYLIEVNPRAARTVPFVSKA
                     TGVPLAKVAARVMAGKSLAEQGVTKEVIPPYYSVKEVVLPFNKFPGVDPLLGPEMRST
                     GEVMGVGRTFAEAFAKAQLGSNSTMKKHGRALLSVREGDKERVVDLAAKLLKQGFELD
                     ATHGTAIVLGEAGINPRLVNKVHEGRPHIQDRIKNGEYTYIINTTSGRRAIEDSRVIR
                     RSALQYKVHYDTTLNGGFATAMALNADATEKVISVQEMHAQIK"
     misc_feature    30817..34023
                     /gene="carB"
                     /locus_tag="b0033"
                     /gene_synonym="cap; ECK0034; JW0031; pyrA"
                     /note="carbamoyl phosphate synthase large subunit;
                     Reviewed; Region: carB; PRK05294"
                     /db_xref="CDD:235393"
     misc_feature    30835..31182
                     /gene="carB"
                     /locus_tag="b0033"
                     /gene_synonym="cap; ECK0034; JW0031; pyrA"
                     /note="Carbamoyl-phosphate synthase L chain, N-terminal
                     domain; Region: CPSase_L_chain; pfam00289"
                     /db_xref="CDD:249744"
     misc_feature    31198..31821
                     /gene="carB"
                     /locus_tag="b0033"
                     /gene_synonym="cap; ECK0034; JW0031; pyrA"
                     /note="Carbamoyl-phosphate synthase L chain, ATP binding
                     domain; Region: CPSase_L_D2; pfam02786"
                     /db_xref="CDD:190425"
     misc_feature    32086..32457
                     /gene="carB"
                     /locus_tag="b0033"
                     /gene_synonym="cap; ECK0034; JW0031; pyrA"
                     /note="Carbamoyl-phosphate synthetase large chain,
                     oligomerisation domain; Region: CPSase_L_D3; smart01096"
                     /db_xref="CDD:198164"
     misc_feature    32494..32820
                     /gene="carB"
                     /locus_tag="b0033"
                     /gene_synonym="cap; ECK0034; JW0031; pyrA"
                     /note="Carbamoyl-phosphate synthase L chain, N-terminal
                     domain; Region: CPSase_L_chain; pfam00289"
                     /db_xref="CDD:249744"
     misc_feature    32836..33444
                     /gene="carB"
                     /locus_tag="b0033"
                     /gene_synonym="cap; ECK0034; JW0031; pyrA"
                     /note="ATP-grasp domain; Region: ATP-grasp_4; cl17255"
                     /db_xref="CDD:266590"
     misc_feature    33643..33972
                     /gene="carB"
                     /locus_tag="b0033"
                     /gene_synonym="cap; ECK0034; JW0031; pyrA"
                     /note="Methylglyoxal synthase-like domain from type II
                     glutamine-dependent carbamoyl phosphate synthetase (CSP).
                     CSP, a CarA and CarB heterodimer, catalyzes the production
                     of carbamoyl phosphate which is subsequently employed in
                     the metabolic pathways...; Region: MGS_CPS_II; cd01424"
                     /db_xref="CDD:238712"
     misc_feature    order(33658..33660,33676..33678,33736..33738,33742..33747,
                     33793..33795,33859..33867)
                     /gene="carB"
                     /locus_tag="b0033"
                     /gene_synonym="cap; ECK0034; JW0031; pyrA"
                     /note="IMP binding site; other site"
                     /db_xref="CDD:238712"
     misc_feature    order(33739..33741,33751..33753,33775..33777,33781..33786,
                     33790..33792,33826..33828)
                     /gene="carB"
                     /locus_tag="b0033"
                     /gene_synonym="cap; ECK0034; JW0031; pyrA"
                     /note="dimer interface [polypeptide binding]; other site"
                     /db_xref="CDD:238712"
     misc_feature    order(33934..33936,33949..33951,33961..33963)
                     /gene="carB"
                     /locus_tag="b0033"
                     /gene_synonym="cap; ECK0034; JW0031; pyrA"
                     /note="interdomain contacts; other site"
                     /db_xref="CDD:238712"
     misc_feature    33934..33942
                     /gene="carB"
                     /locus_tag="b0033"
                     /gene_synonym="cap; ECK0034; JW0031; pyrA"
                     /note="partial ornithine binding site; other site"
                     /db_xref="CDD:238712"
     gene            34300..34695
                     /gene="caiF"
                     /locus_tag="b0034"
                     /gene_synonym="ECK0035; JW0033"
                     /db_xref="EcoGene:EG13451"
                     /db_xref="GeneID:944795"
     CDS             34300..34695
                     /gene="caiF"
                     /locus_tag="b0034"
                     /gene_synonym="ECK0035; JW0033"
                     /function="regulator; Central intermediary metabolism:
                     Pool, multipurpose conversions"
                     /GO_component="GO:0005737 - cytoplasm"
                     /GO_function="GO:0016563 - transcription activator
                     activity"
                     /GO_process="GO:0009310 - amine catabolic process"
                     /GO_process="GO:0006350 - transcription"
                     /note="transcriptional regulator of cai operon"
                     /codon_start=1
                     /transl_table=11
                     /product="cai operon transcriptional activator"
                     /protein_id="NP_414576.4"
                     /db_xref="GI:90111079"
                     /db_xref="ASAP:ABE-0000125"
                     /db_xref="UniProtKB/Swiss-Prot:P0AE58"
                     /db_xref="EcoGene:EG13451"
                     /db_xref="GeneID:944795"
                     /translation="MCEGYVEKPLYLLIAEWMMAENRWVIAREISIHFDIEHSKAVNT
                     LTYILSEVTEISCEVKMIPNKLEGRGCQCQRLVKVVDIDEQIYARLRNNSREKLVGVR
                     KTPRIPAVPLTELNREQKWQMMLSKSMRR"
     misc_feature    34354..34692
                     /gene="caiF"
                     /locus_tag="b0034"
                     /gene_synonym="ECK0035; JW0033"
                     /note="DNA-binding transcriptional activator CaiF;
                     Provisional; Region: PRK11476"
                     /db_xref="CDD:183154"
     repeat_region   34727..34762
                     /note="REP3 (repetitive extragenic palindromic) element;
                     contains 1 REP sequences"
     gene            complement(34781..35371)
                     /gene="caiE"
                     /locus_tag="b0035"
                     /gene_synonym="ECK0036; JW5004"
                     /db_xref="EcoGene:EG12608"
                     /db_xref="GeneID:948999"
     CDS             complement(34781..35371)
                     /gene="caiE"
                     /locus_tag="b0035"
                     /gene_synonym="ECK0036; JW5004"
                     /function="putative enzyme; Central intermediary
                     metabolism: Pool, multipurpose conversions"
                     /GO_process="GO:0009310 - amine catabolic process"
                     /GO_process="GO:0042413 - carnitine catabolic process"
                     /note="possible synthesis of cofactor for carnitine
                     racemase and dehydratase"
                     /codon_start=1
                     /transl_table=11
                     /product="stimulator of CaiD and CaiB enzyme activities"
                     /protein_id="NP_414577.2"
                     /db_xref="GI:90111080"
                     /db_xref="ASAP:ABE-0000128"
                     /db_xref="UniProtKB/Swiss-Prot:P39206"
                     /db_xref="EcoGene:EG12608"
                     /db_xref="GeneID:948999"
                     /translation="MSYYAFEGLIPVVHPTAFVHPSAVLIGDVIVGAGVYIGPLASLR
                     GDYGRLIVQAGANIQDGCIMHGYCDTDTIVGENGHIGHGAILHGCLIGRDALVGMNSV
                     IMDGAVIGEESIVAAMSFVKAGFRGEKRQLLMGTPARAVRNVSDDELHWKRLNTKEYQ
                     DLVGRCHVSLHETQPLRQMEENRPRLQGTTDVTPKR"
     misc_feature    complement(34784..35371)
                     /gene="caiE"
                     /locus_tag="b0035"
                     /gene_synonym="ECK0036; JW5004"
                     /note="carnitine operon protein CaiE; Provisional; Region:
                     PRK13627"
                     /db_xref="CDD:184189"
     misc_feature    complement(34877..35341)
                     /gene="caiE"
                     /locus_tag="b0035"
                     /gene_synonym="ECK0036; JW5004"
                     /note="paaY-like: This group is composed by
                     uncharacterized proteins with similarity to the protein
                     product of the E. coli paaY gene, which is part of the paa
                     gene cluster responsible for phenylacetic acid
                     degradation. Proteins in this group are expected to...;
                     Region: LbH_paaY_like; cd04745"
                     /db_xref="CDD:100058"
     misc_feature    complement(order(35075..35077,35111..35113,35117..35128,
                     35177..35179,35189..35194,35234..35236,35240..35242,
                     35246..35251,35258..35260,35294..35296,35303..35308,
                     35312..35314,35318..35320))
                     /gene="caiE"
                     /locus_tag="b0035"
                     /gene_synonym="ECK0036; JW5004"
                     /note="putative trimer interface [polypeptide binding];
                     other site"
                     /db_xref="CDD:100058"
     misc_feature    complement(order(35111..35113,35126..35128,35177..35179))
                     /gene="caiE"
                     /locus_tag="b0035"
                     /gene_synonym="ECK0036; JW5004"
                     /note="putative metal binding site [ion binding]; other
                     site"
                     /db_xref="CDD:100058"
     gene            complement(35377..36162)
                     /gene="caiD"
                     /locus_tag="b0036"
                     /gene_synonym="ECK0037; JW0035; yaaL"
                     /db_xref="EcoGene:EG11557"
                     /db_xref="GeneID:948995"
     CDS             complement(35377..36162)
                     /gene="caiD"
                     /locus_tag="b0036"
                     /gene_synonym="ECK0037; JW0035; yaaL"
                     /EC_number="4.2.1.-"
                     /function="enzyme; Degradation of small molecules: Amines"
                     /GO_process="GO:0009310 - amine catabolic process"
                     /GO_process="GO:0042413 - carnitine catabolic process"
                     /note="carnitine racemase"
                     /codon_start=1
                     /transl_table=11
                     /product="carnitinyl-CoA dehydratase"
                     /protein_id="NP_414578.2"
                     /db_xref="GI:221800779"
                     /db_xref="ASAP:ABE-0000130"
                     /db_xref="UniProtKB/Swiss-Prot:P31551"
                     /db_xref="EcoGene:EG11557"
                     /db_xref="GeneID:948995"
                     /translation="MSESLHLTRNGSILEITLDRPKANAIDAKTSFEMGEVFLNFRDD
                     PQLRVAIITGAGEKFFSAGWDLKAAAEGEAPDADFGPGGFAGLTEIFNLDKPVIAAVN
                     GYAFGGGFELALAADFIVCADNASFALPEAKLGIVPDSGGVLRLPKILPPAIVNEMVM
                     TGRRMGAEEALRWGIVNRVVSQAELMDNARELAQQLVNSAPLAIAALKEIYRTTSEMP
                     VEEAYRYIRSGVLKHYPSVLHSEDAIEGPLAFAEKRDPVWKGR"
     misc_feature    complement(35380..36162)
                     /gene="caiD"
                     /locus_tag="b0036"
                     /gene_synonym="ECK0037; JW0035; yaaL"
                     /note="carnitinyl-CoA dehydratase; Provisional; Region:
                     PRK03580"
                     /db_xref="CDD:179599"
     misc_feature    complement(35575..36150)
                     /gene="caiD"
                     /locus_tag="b0036"
                     /gene_synonym="ECK0037; JW0035; yaaL"
                     /note="Crotonase/Enoyl-Coenzyme A (CoA) hydratase
                     superfamily. This superfamily contains a diverse set of
                     enzymes including enoyl-CoA hydratase, napthoate synthase,
                     methylmalonyl-CoA decarboxylase, 3-hydoxybutyryl-CoA
                     dehydratase, and dienoyl-CoA isomerase; Region:
                     crotonase-like; cd06558"
                     /db_xref="CDD:119339"
     misc_feature    complement(order(35761..35763,35770..35775,35839..35847,
                     35851..35853,35965..35979,35989..35991,36088..36090,
                     36094..36096))
                     /gene="caiD"
                     /locus_tag="b0036"
                     /gene_synonym="ECK0037; JW0035; yaaL"
                     /note="substrate binding site [chemical binding]; other
                     site"
                     /db_xref="CDD:119339"
     misc_feature    complement(order(35839..35841,35971..35973))
                     /gene="caiD"
                     /locus_tag="b0036"
                     /gene_synonym="ECK0037; JW0035; yaaL"
                     /note="oxyanion hole (OAH) forming residues; other site"
                     /db_xref="CDD:119339"
     misc_feature    complement(order(35575..35580,35587..35589,35632..35634,
                     35641..35643,35674..35676,35683..35688,35692..35697,
                     35701..35706,35719..35724,35728..35736,35740..35742,
                     35758..35769,35803..35814,35875..35877,35899..35901))
                     /gene="caiD"
                     /locus_tag="b0036"
                     /gene_synonym="ECK0037; JW0035; yaaL"
                     /note="trimer interface [polypeptide binding]; other site"
                     /db_xref="CDD:119339"
     gene            complement(36271..37824)
                     /gene="caiC"
                     /locus_tag="b0037"
                     /gene_synonym="ECK0038; JW0036; yaaM"
                     /db_xref="EcoGene:EG11558"
                     /db_xref="GeneID:944886"
     CDS             complement(36271..37824)
                     /gene="caiC"
                     /locus_tag="b0037"
                     /gene_synonym="ECK0038; JW0036; yaaM"
                     /EC_number="6.3.2.-"
                     /function="putative enzyme; Central intermediary
                     metabolism: Pool, multipurpose conversions"
                     /GO_component="GO:0009274 - peptidoglycan-based cell wall"
                     /GO_component="GO:0019866 - organelle inner membrane"
                     /GO_process="GO:0009310 - amine catabolic process"
                     /note="probable crotonobetaine/carnitine-CoA ligase"
                     /codon_start=1
                     /transl_table=11
                     /product="putative crotonobetaine/carnitine-CoA ligase"
                     /protein_id="NP_414579.4"
                     /db_xref="GI:221800780"
                     /db_xref="ASAP:ABE-0000133"
                     /db_xref="UniProtKB/Swiss-Prot:P31552"
                     /db_xref="EcoGene:EG11558"
                     /db_xref="GeneID:944886"
                     /translation="MDIIGGQHLRQMWDDLADVYGHKTALICESSGGVVNRYSYLELN
                     QEINRTANLFYTLGIRKGDKVALHLDNCPEFIFCWFGLAKIGAIMVPINARLLCEESA
                     WILQNSQACLLVTSAQFYPMYQQIQQEDATQLRHICLTDVALPADDGVSSFTQLKNQQ
                     PATLCYAPPLSTDDTAEILFTSGTTSRPKGVVITHYNLRFAGYYSAWQCALRDDDVYL
                     TVMPAFHIDCQCTAAMAAFSAGATFVLVEKYSARAFWGQVQKYRATVTECIPMMIRTL
                     MVQPPSANDQQHRLREVMFYLNLSEQEKDAFCERFGVRLLTSYGMTETIVGIIGDRPG
                     DKRRWPSIGRVGFCYEAEIRDDHNRPLPAGEIGEICIKGIPGKTIFKEYFLNPQATAK
                     VLEADGWLHTGDTGYRDEEDFFYFVDRRCNMIKRGGENVSCVELENIIAAHPKIQDIV
                     VVGIKDSIRDEAIKAFVVLNEGETLSEEEFFRFCEQNMAKFKVPSYLEIRKDLPRNCS
                     GKIIRKNLK"
     misc_feature    complement(36274..37824)
                     /gene="caiC"
                     /locus_tag="b0037"
                     /gene_synonym="ECK0038; JW0036; yaaM"
                     /note="putative crotonobetaine/carnitine-CoA ligase;
                     Validated; Region: caiC; PRK08008"
                     /db_xref="CDD:181195"
     misc_feature    complement(36274..37719)
                     /gene="caiC"
                     /locus_tag="b0037"
                     /gene_synonym="ECK0038; JW0036; yaaM"
                     /note="Uncharacterized subfamily of fatty acid CoA ligase
                     (FACL); Region: FACL_DitJ_like; cd05934"
                     /db_xref="CDD:213300"
     misc_feature    complement(order(37258..37263,37267..37284,37291..37293))
                     /gene="caiC"
                     /locus_tag="b0037"
                     /gene_synonym="ECK0038; JW0036; yaaM"
                     /note="acyl-activating enzyme (AAE) consensus motif; other
                     site"
                     /db_xref="CDD:213300"
     misc_feature    complement(order(36295..36297,36535..36537,36568..36570,
                     36577..36579,36613..36615,36859..36876,36934..36939,
                     37282..37284))
                     /gene="caiC"
                     /locus_tag="b0037"
                     /gene_synonym="ECK0038; JW0036; yaaM"
                     /note="putative AMP binding site [chemical binding]; other
                     site"
                     /db_xref="CDD:213300"
     misc_feature    complement(order(36352..36354,36535..36546,36568..36570,
                     36577..36579,36613..36615,36859..36876,36934..36939,
                     36994..36996,37003..37008,37012..37014,37159..37164,
                     37282..37284))
                     /gene="caiC"
                     /locus_tag="b0037"
                     /gene_synonym="ECK0038; JW0036; yaaM"
                     /note="putative active site [active]"
                     /db_xref="CDD:213300"
     misc_feature    complement(order(36352..36354,36370..36372,36538..36546,
                     36937..36939,36994..36996,37003..37008,37162..37164))
                     /gene="caiC"
                     /locus_tag="b0037"
                     /gene_synonym="ECK0038; JW0036; yaaM"
                     /note="putative CoA binding site [chemical binding]; other
                     site"
                     /db_xref="CDD:213300"
     gene            complement(37898..39115)
                     /gene="caiB"
                     /locus_tag="b0038"
                     /gene_synonym="ECK0039; JW0037; yaaN"
                     /db_xref="EcoGene:EG11559"
                     /db_xref="GeneID:948997"
     CDS             complement(37898..39115)
                     /gene="caiB"
                     /locus_tag="b0038"
                     /gene_synonym="ECK0039; JW0037; yaaN"
                     /EC_number="2.8.3.-"
                     /function="enzyme; Central intermediary metabolism: Pool,
                     multipurpose conversions"
                     /experiment="N-terminus verified by Edman degradation:
                     PMID 8188598,10209289"
                     /GO_component="GO:0005737 - cytoplasm"
                     /GO_process="GO:0042413 - carnitine catabolic process"
                     /GO_process="GO:0009310 - amine catabolic process"
                     /note="l-carnitine dehydratase"
                     /codon_start=1
                     /transl_table=11
                     /product="crotonobetainyl CoA:carnitine CoA transferase"
                     /protein_id="NP_414580.1"
                     /db_xref="GI:16128032"
                     /db_xref="ASAP:ABE-0000136"
                     /db_xref="UniProtKB/Swiss-Prot:P31572"
                     /db_xref="EcoGene:EG11559"
                     /db_xref="GeneID:948997"
                     /translation="MDHLPMPKFGPLAGLRVVFSGIEIAGPFAGQMFAEWGAEVIWIE
                     NVAWADTIRVQPNYPQLSRRNLHALSLNIFKDEGREAFLKLMETTDIFIEASKGPAFA
                     RRGITDEVLWQHNPKLVIAHLSGFGQYGTEEYTNLPAYNTIAQAFSGYLIQNGDVDQP
                     MPAFPYTADYFSGLTATTAALAALHKVRETGKGESIDIAMYEVMLRMGQYFMMDYFNG
                     GEMCPRMSKGKDPYYAGCGLYKCADGYIVMELVGITQIEECFKDIGLAHLLGTPEIPE
                     GTQLIHRIECPYGPLVEEKLDAWLATHTIAEVKERFAELNIACAKVLTVPELESNPQY
                     VARESITQWQTMDGRTCKGPNIMPKFKNNPGQIWRGMPSHGMDTAAILKNIGYSENDI
                     QELVSKGLAKVED"
     misc_feature    complement(37901..39115)
                     /gene="caiB"
                     /locus_tag="b0038"
                     /gene_synonym="ECK0039; JW0037; yaaN"
                     /note="crotonobetainyl-CoA:carnitine CoA-transferase;
                     Provisional; Region: PRK03525"
                     /db_xref="CDD:179589"
     repeat_region   39151..39232
                     /note="REP4 (repetitive extragenic palindromic) element;
                     contains 2 REP sequences"
     gene            complement(39244..40386)
                     /gene="caiA"
                     /locus_tag="b0039"
                     /gene_synonym="ECK0040; JW0038; yaaO"
                     /db_xref="EcoGene:EG11560"
                     /db_xref="GeneID:949064"
     CDS             complement(39244..40386)
                     /gene="caiA"
                     /locus_tag="b0039"
                     /gene_synonym="ECK0040; JW0038; yaaO"
                     /EC_number="1.3.99.-"
                     /function="putative regulator; Central intermediary
                     metabolism: Pool, multipurpose conversions"
                     /experiment="N-terminus verified by Edman degradation:
                     PMID 10209289"
                     /GO_component="GO:0005737 - cytoplasm"
                     /GO_process="GO:0006097 - glyoxylate cycle"
                     /GO_process="GO:0009310 - amine catabolic process"
                     /GO_process="GO:0042413 - carnitine catabolic process"
                     /note="probable carnitine operon oxidoreductase"
                     /codon_start=1
                     /transl_table=11
                     /product="crotonobetaine reductase subunit II,
                     FAD-binding"
                     /protein_id="NP_414581.1"
                     /db_xref="GI:16128033"
                     /db_xref="ASAP:ABE-0000139"
                     /db_xref="UniProtKB/Swiss-Prot:P60584"
                     /db_xref="EcoGene:EG11560"
                     /db_xref="GeneID:949064"
                     /translation="MDFNLNDEQELFVAGIRELMASENWEAYFAECDRDSVYPERFVK
                     ALADMGIDSLLIPEEHGGLDAGFVTLAAVWMELGRLGAPTYVLYQLPGGFNTFLREGT
                     QEQIDKIMAFRGTGKQMWNSAITEPGAGSDVGSLKTTYTRRNGKIYLNGSKCFITSSA
                     YTPYIVVMARDGASPDKPVYTEWFVDMSKPGIKVTKLEKLGLRMDSCCEITFDDVELD
                     EKDMFGREGNGFNRVKEEFDHERFLVALTNYGTAMCAFEDAARYANQRVQFGEAIGRF
                     QLIQEKFAHMAIKLNSMKNMLYEAAWKADNGTITSGDAAMCKYFCANAAFEVVDSAMQ
                     VLGGVGIAGNHRISRFWRDLRVDRVSGGSDEMQILTLGRAVLKQYR"
     misc_feature    complement(39247..40386)
                     /gene="caiA"
                     /locus_tag="b0039"
                     /gene_synonym="ECK0040; JW0038; yaaO"
                     /note="crotonobetainyl-CoA dehydrogenase; Validated;
                     Region: PRK03354"
                     /db_xref="CDD:179566"
     misc_feature    complement(39268..40368)
                     /gene="caiA"
                     /locus_tag="b0039"
                     /gene_synonym="ECK0040; JW0038; yaaO"
                     /note="Acyl-CoA dehydrogenase; Region: ACAD; cd00567"
                     /db_xref="CDD:173838"
     misc_feature    complement(order(39292..39294,39298..39300,39304..39312,
                     39916..39918,39922..39924,40015..40017,40021..40023,
                     40237..40239))
                     /gene="caiA"
                     /locus_tag="b0039"
                     /gene_synonym="ECK0040; JW0038; yaaO"
                     /note="active site"
                     /db_xref="CDD:173838"
     gene            complement(40417..41931)
                     /gene="caiT"
                     /locus_tag="b0040"
                     /gene_synonym="ECK0041; JW0039; yaaP"
                     /db_xref="EcoGene:EG11561"
                     /db_xref="GeneID:944765"
     CDS             complement(40417..41931)
                     /gene="caiT"
                     /locus_tag="b0040"
                     /gene_synonym="ECK0041; JW0039; yaaP"
                     /function="putative transport; Central intermediary
                     metabolism: Pool, multipurpose conversions"
                     /GO_component="GO:0009274 - peptidoglycan-based cell wall"
                     /GO_component="GO:0019866 - organelle inner membrane"
                     /GO_process="GO:0016052 - carbohydrate catabolic process"
                     /note="probable carnitine transporter"
                     /codon_start=1
                     /transl_table=11
                     /product="putative transporter"
                     /protein_id="NP_414582.1"
                     /db_xref="GI:16128034"
                     /db_xref="ASAP:ABE-0000141"
                     /db_xref="UniProtKB/Swiss-Prot:P31553"
                     /db_xref="EcoGene:EG11561"
                     /db_xref="GeneID:944765"
                     /translation="MKNEKRKTGIEPKVFFPPLIIVGILCWLTVRDLDAANVVINAVF
                     SYVTNVWGWAFEWYMVVMLFGWFWLVFGPYAKKRLGNEPPEFSTASWIFMMFASCTSA
                     AVLFWGSIEIYYYISTPPFGLEPNSTGAKELGLAYSLFHWGPLPWATYSFLSVAFAYF
                     FFVRKMEVIRPSSTLVPLVGEKHAKGLFGTIVDNFYLVALIFAMGTSLGLATPLVTEC
                     MQWLFGIPHTLQLDAIIITCWIILNAICVACGLQKGVRIASDVRSYLSFLMLGWVFIV
                     SGASFIMNYFTDSVGMLLMYLPRMLFYTDPIAKGGFPQGWTVFYWAWWVIYAIQMSIF
                     LARISRGRTVRELCFGMVLGLTASTWILWTVLGSNTLLLIDKNIINIPNLIEQYGVAR
                     AIIETWAALPLSTATMWGFFILCFIATVTLVNACSYTLAMSTCREVRDGEEPPLLVRI
                     GWSILVGIIGIVLLALGGLKPIQTAIIAGGCPLFFVNIMVTLSFIKDAKQNWKD"
     misc_feature    complement(40420..41931)
                     /gene="caiT"
                     /locus_tag="b0040"
                     /gene_synonym="ECK0041; JW0039; yaaP"
                     /note="L-carnitine/gamma-butyrobetaine antiporter;
                     Provisional; Region: PRK03356"
                     /db_xref="CDD:179568"
     gene            42403..43173
                     /gene="fixA"
                     /locus_tag="b0041"
                     /gene_synonym="ECK0042; JW0040; yaaQ"
                     /db_xref="EcoGene:EG11562"
                     /db_xref="GeneID:947316"
     CDS             42403..43173
                     /gene="fixA"
                     /locus_tag="b0041"
                     /gene_synonym="ECK0042; JW0040; yaaQ"
                     /function="putative enzyme; Energy metabolism, carbon:
                     Electron transport"
                     /GO_process="GO:0016052 - carbohydrate catabolic process"
                     /note="probable flavoprotein subunit, carnitine
                     metabolism"
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic carnitine reduction putative electron
                     transfer flavoprotein subunit"
                     /protein_id="NP_414583.2"
                     /db_xref="GI:90111081"
                     /db_xref="ASAP:ABE-0000145"
                     /db_xref="UniProtKB/Swiss-Prot:P60566"
                     /db_xref="EcoGene:EG11562"
                     /db_xref="GeneID:947316"
                     /translation="MKIITCYKCVPDEQDIAVNNADGSLDFSKADAKISQYDLNAIEA
                     ACQLKQQAAEAQVTALSVGGKALTNAKGRKDVLSRGPDELIVVIDDQFEQALPQQTAS
                     ALAAAAQKAGFDLILCGDGSSDLYAQQVGLLVGEILNIPAVNGVSKIISLTADTLTVE
                     RELEDETETLSIPLPAVVAVSTDINSPQIPSMKAILGAAKKPVQVWSAADIGFNAEAA
                     WSEQQVAAPKQRERQRIVIEGDGEEQIAAFAENLRKVI"
     misc_feature    42406..43023
                     /gene="fixA"
                     /locus_tag="b0041"
                     /gene_synonym="ECK0042; JW0040; yaaQ"
                     /note="The electron transfer flavoprotein (ETF) serves as
                     a specific electron acceptor for various mitochondrial
                     dehydrogenases. ETF transfers electrons to the main
                     respiratory chain via ETF-ubiquinone oxidoreductase. ETF
                     is an heterodimer that consists of an...; Region:
                     ETF_beta; cd01714"
                     /db_xref="CDD:238847"
     misc_feature    order(42418..42423,42505..42507,42514..42516,42586..42588,
                     42754..42759,42763..42768,42781..42792)
                     /gene="fixA"
                     /locus_tag="b0041"
                     /gene_synonym="ECK0042; JW0040; yaaQ"
                     /note="Ligand binding site [chemical binding]; other site"
                     /db_xref="CDD:238847"
     gene            43188..44129
                     /gene="fixB"
                     /locus_tag="b0042"
                     /gene_synonym="ECK0043; JW0041; yaaR"
                     /db_xref="EcoGene:EG11563"
                     /db_xref="GeneID:948939"
     CDS             43188..44129
                     /gene="fixB"
                     /locus_tag="b0042"
                     /gene_synonym="ECK0043; JW0041; yaaR"
                     /function="putative enzyme; Energy metabolism, carbon:
                     Electron transport"
                     /GO_process="GO:0016052 - carbohydrate catabolic process"
                     /note="probable flavoprotein subunit, carnitine
                     metabolism"
                     /codon_start=1
                     /transl_table=11
                     /product="putative electron transfer flavoprotein,
                     NAD/FAD-binding domain and ETFP adenine nucleotide-binding
                     domain-like protein"
                     /protein_id="NP_414584.1"
                     /db_xref="GI:16128036"
                     /db_xref="ASAP:ABE-0000147"
                     /db_xref="UniProtKB/Swiss-Prot:P31574"
                     /db_xref="EcoGene:EG11563"
                     /db_xref="GeneID:948939"
                     /translation="MNTFSQVWVFSDTPSRLPELMNGAQALANQINTFVLNDADGAQA
                     IQLGANHVWKLNGKPDDRMIEDYAGVMADTIRQHGADGLVLLPNTRRGKLLAAKLGYR
                     LKAAVSNDASTVSVQDGKATVKHMVYGGLAIGEERIATPYAVLTISSGTFDAAQPDAS
                     RTGETHTVEWQAPAVAITRTATQARQSNSVDLDKARLVVSVGRGIGSKENIALAEQLC
                     KAIGAELACSRPVAENEKWMEHERYVGISNLMLKPELYLAVGISGQIQHMVGANASQT
                     IFAINKDKNAPIFQYADYGIVGDAVKILPALTAALAR"
     misc_feature    43188..44126
                     /gene="fixB"
                     /locus_tag="b0042"
                     /gene_synonym="ECK0043; JW0041; yaaR"
                     /note="putative electron transfer flavoprotein FixB;
                     Provisional; Region: fixB; PRK03363"
                     /db_xref="CDD:235120"
     misc_feature    43242..43649
                     /gene="fixB"
                     /locus_tag="b0042"
                     /gene_synonym="ECK0043; JW0041; yaaR"
                     /note="Electron transfer flavoprotein domain; Region: ETF;
                     pfam01012"
                     /db_xref="CDD:250293"
     misc_feature    43752..44012
                     /gene="fixB"
                     /locus_tag="b0042"
                     /gene_synonym="ECK0043; JW0041; yaaR"
                     /note="Electron transfer flavoprotein FAD-binding domain;
                     Region: ETF_alpha; pfam00766"
                     /db_xref="CDD:189709"
     gene            44180..45466
                     /gene="fixC"
                     /locus_tag="b0043"
                     /gene_synonym="ECK0044; JW0042; yaaS"
                     /db_xref="EcoGene:EG11564"
                     /db_xref="GeneID:948958"
     CDS             44180..45466
                     /gene="fixC"
                     /locus_tag="b0043"
                     /gene_synonym="ECK0044; JW0042; yaaS"
                     /function="putative carrier; Energy metabolism, carbon:
                     Electron transport"
                     /GO_process="GO:0042413 - carnitine catabolic process"
                     /note="flavoprotein; electron transport"
                     /codon_start=1
                     /transl_table=11
                     /product="putative oxidoreductase"
                     /protein_id="NP_414585.1"
                     /db_xref="GI:16128037"
                     /db_xref="ASAP:ABE-0000149"
                     /db_xref="UniProtKB/Swiss-Prot:P68644"
                     /db_xref="EcoGene:EG11564"
                     /db_xref="GeneID:948958"
                     /translation="MSEDIFDAIIVGAGLAGSVAALVLAREGAQVLVIERGNSAGAKN
                     VTGGRLYAHSLEHIIPGFADSAPVERLITHEKLAFMTEKSAMTMDYCNGDETSPSQRS
                     YSVLRSKFDAWLMEQAEEAGAQLITGIRVDNLVQRDGKVVGVEADGDVIEAKTVILAD
                     GVNSILAEKLGMAKRVKPTDVAVGVKELIELPKSVIEDRFQLQGNQGAACLFAGSPTD
                     GLMGGGFLYTNENTLSLGLVCGLHHLHDAKKSVPQMLEDFKQHPAVAPLIAGGKLVEY
                     SAHVVPEAGINMLPELVGDGVLIAGDAAGMCMNLGFTIRGMDLAIAAGEAAAKTVLSA
                     MKSDDFSKQKLAEYRQHLESGPLRDMRMYQKLPAFLDNPRMFSGYPELAVGVARDLFT
                     IDGSAPELMRKKILRHGKKVGFINLIKDGMKGVTVL"
     misc_feature    44180..45463
                     /gene="fixC"
                     /locus_tag="b0043"
                     /gene_synonym="ECK0044; JW0042; yaaS"
                     /note="NAD(P)-binding Rossmann-like domain; Region:
                     NAD_binding_8; cl19134"
                     /db_xref="CDD:267487"
     misc_feature    44180..45463
                     /gene="fixC"
                     /locus_tag="b0043"
                     /gene_synonym="ECK0044; JW0042; yaaS"
                     /note="putative oxidoreductase FixC; Provisional; Region:
                     PRK10157"
                     /db_xref="CDD:182273"
     gene            45463..45750
                     /gene="fixX"
                     /locus_tag="b0044"
                     /gene_synonym="ECK0045; JW0043; yaaT"
                     /db_xref="EcoGene:EG11565"
                     /db_xref="GeneID:948590"
     CDS             45463..45750
                     /gene="fixX"
                     /locus_tag="b0044"
                     /gene_synonym="ECK0045; JW0043; yaaT"
                     /function="putative carrier; Not classified"
                     /GO_process="GO:0042413 - carnitine catabolic process"
                     /note="putative ferredoxin"
                     /codon_start=1
                     /transl_table=11
                     /product="putative 4Fe-4S ferredoxin-type protein"
                     /protein_id="NP_414586.1"
                     /db_xref="GI:16128038"
                     /db_xref="ASAP:ABE-0000151"
                     /db_xref="UniProtKB/Swiss-Prot:P68646"
                     /db_xref="EcoGene:EG11565"
                     /db_xref="GeneID:948590"
                     /translation="MTSPVNVDVKLGVNKFNVDEEHPHIVVKADADKQALELLVKACP
                     AGLYKKQDDGSVRFDYAGCLECGTCRILGLGSALEQWEYPRGTFGVEFRYG"
     misc_feature    45463..45747
                     /gene="fixX"
                     /locus_tag="b0044"
                     /gene_synonym="ECK0045; JW0043; yaaT"
                     /note="ferredoxin-like protein FixX; Provisional; Region:
                     PRK15449"
                     /db_xref="CDD:185346"
     gene            45807..47138
                     /gene="yaaU"
                     /locus_tag="b0045"
                     /gene_synonym="ECK0046; JW0044; yabE"
                     /db_xref="EcoGene:EG11566"
                     /db_xref="GeneID:944766"
     CDS             45807..47138
                     /gene="yaaU"
                     /locus_tag="b0045"
                     /gene_synonym="ECK0046; JW0044; yabE"
                     /function="putative transport; Not classified"
                     /GO_component="GO:0009274 - peptidoglycan-based cell wall"
                     /GO_component="GO:0019866 - organelle inner membrane"
                     /note="putative transport protein"
                     /codon_start=1
                     /transl_table=11
                     /product="putative MFS sugar transporter; membrane
                     protein"
                     /protein_id="NP_414587.1"
                     /db_xref="GI:16128039"
                     /db_xref="ASAP:ABE-0000156"
                     /db_xref="UniProtKB/Swiss-Prot:P31679"
                     /db_xref="EcoGene:EG11566"
                     /db_xref="GeneID:944766"
                     /translation="MQPSRNFDDLKFSSIHRRILLWGSGGPFLDGYVLVMIGVALEQL
                     TPALKLDADWIGLLGAGTLAGLFVGTSLFGYISDKVGRRKMFLIDIIAIGVISVATMF
                     VSSPVELLVMRVLIGIVIGADYPIATSMITEFSSTRQRAFSISFIAAMWYVGATCADL
                     VGYWLYDVEGGWRWMLGSAAIPCLLILIGRFELPESPRWLLRKGRVKECEEMMIKLFG
                     EPVAFDEEQPQQTRFRDLFNRRHFPFVLFVAAIWTCQVIPMFAIYTFGPQIVGLLGLG
                     VGKNAALGNVVISLFFMLGCIPPMLWLNTAGRRPLLIGSFAMMTLALAVLGLIPDMGI
                     WLVVMAFAVYAFFSGGPGNLQWLYPNELFPTDIRASAVGVIMSLSRIGTIVSTWALPI
                     FINNYGISNTMLMGAGISLFGLLISVAFAPETRGMSLAQTSNMTIRGQRMG"
     misc_feature    45864..47069
                     /gene="yaaU"
                     /locus_tag="b0045"
                     /gene_synonym="ECK0046; JW0044; yabE"
                     /note="The Major Facilitator Superfamily (MFS) is a large
                     and diverse group of secondary transporters that includes
                     uniporters, symporters, and antiporters. MFS proteins
                     facilitate the transport across cytoplasmic or internal
                     membranes of a variety of...; Region: MFS; cd06174"
                     /db_xref="CDD:119392"
     misc_feature    45882..47111
                     /gene="yaaU"
                     /locus_tag="b0045"
                     /gene_synonym="ECK0046; JW0044; yabE"
                     /note="Sugar (and other) transporter; Region: Sugar_tr;
                     pfam00083"
                     /db_xref="CDD:249572"
     misc_feature    order(45906..45908,45915..45923,45927..45932,45981..45983,
                     45990..45995,46002..46004,46014..46019,46023..46028,
                     46164..46169,46176..46181,46188..46193,46200..46202,
                     46236..46241,46248..46253,46269..46271,46572..46574,
                     46581..46586,46593..46598,46605..46607,46647..46649,
                     46659..46661,46671..46673,46680..46682,46692..46694,
                     46839..46841,46848..46853,46860..46862,46872..46877,
                     46884..46886,46917..46922,46929..46934,46941..46946,
                     46953..46955)
                     /gene="yaaU"
                     /locus_tag="b0045"
                     /gene_synonym="ECK0046; JW0044; yabE"
                     /note="putative substrate translocation pore; other site"
                     /db_xref="CDD:119392"
     gene            47246..47776
                     /gene="kefF"
                     /locus_tag="b0046"
                     /gene_synonym="ECK0047; JW0045; yabF"
                     /db_xref="EcoGene:EG11568"
                     /db_xref="GeneID:944767"
     CDS             47246..47776
                     /gene="kefF"
                     /locus_tag="b0046"
                     /gene_synonym="ECK0047; JW0045; yabF"
                     /function="putative enzyme; Not classified"
                     /note="putative NAD(P)H oxidoreductase"
                     /codon_start=1
                     /transl_table=11
                     /product="potassium-efflux system ancillary protein for
                     KefC, glutathione-regulated; quinone oxidoreductase,
                     FMN-dependent"
                     /protein_id="NP_414588.1"
                     /db_xref="GI:16128040"
                     /db_xref="ASAP:ABE-0000159"
                     /db_xref="UniProtKB/Swiss-Prot:P0A754"
                     /db_xref="EcoGene:EG11568"
                     /db_xref="GeneID:944767"
                     /translation="MILIIYAHPYPHHSHANKRMLEQARTLEGVEIRSLYQLYPDFNI
                     DIAAEQEALSRADLIVWQHPMQWYSIPPLLKLWIDKVFSHGWAYGHGGTALHGKHLLW
                     AVTTGGGESHFEIGAHPGFDVLSQPLQATAIYCGLNWLPPFAMHCTFICDDETLEGQA
                     RHYKQRLLEWQEAHHG"
     misc_feature    47246..47773
                     /gene="kefF"
                     /locus_tag="b0046"
                     /gene_synonym="ECK0047; JW0045; yabF"
                     /note="glutathione-regulated potassium-efflux system
                     ancillary protein KefF; Provisional; Region: PRK00871"
                     /db_xref="CDD:234852"
     gene            47769..49631
                     /gene="kefC"
                     /locus_tag="b0047"
                     /gene_synonym="ECK0048; JW0046; trkC"
                     /db_xref="EcoGene:EG10521"
                     /db_xref="GeneID:944773"
     CDS             47769..49631
                     /gene="kefC"
                     /locus_tag="b0047"
                     /gene_synonym="ECK0048; JW0046; trkC"
                     /function="transport; Transport of small molecules:
                     Cations"
                     /GO_component="GO:0009274 - peptidoglycan-based cell wall"
                     /GO_component="GO:0019866 - organelle inner membrane"
                     /GO_function="GO:0015386 - potassium:hydrogen antiporter
                     activity"
                     /note="K+ efflux antiporter, glutathione-regulated"
                     /codon_start=1
                     /transl_table=11
                     /product="potassium:proton antiporter"
                     /protein_id="NP_414589.1"
                     /db_xref="GI:16128041"
                     /db_xref="ASAP:ABE-0000161"
                     /db_xref="UniProtKB/Swiss-Prot:P03819"
                     /db_xref="EcoGene:EG10521"
                     /db_xref="GeneID:944773"
                     /translation="MDSHTLIQALIYLGSAALIVPIAVRLGLGSVLGYLIAGCIIGPW
                     GLRLVTDAESILHFAEIGVVLMLFIIGLELDPQRLWKLRAAVFGCGALQMVICGGLLG
                     LFCMLLGLRWQVAELIGMTLALSSTAIAMQAMNERNLMVTQMGRSAFAVLLFQDIAAI
                     PLVAMIPLLATSSASTTMGAFALSALKVAGALVLVVLLGRYVTRPALRFVARSGLREV
                     FSAVALFLVFGFGLLLEEVGLSMAMGAFLAGVLLASSEYRHALESDIEPFKGLLLGLF
                     FIGVGMSIDFGTLLENPLRIVILLLGFLIIKIAMLWLIARPLQVPNKQRRWFAVLLGQ
                     GSEFAFVVFGAAQMANVLEPEWAKSLTLAVALSMAATPILLVILNRLEQSSTEEAREA
                     DEIDEEQPRVIIAGFGRFGQITGRLLLSSGVKMVVLDHDPDHIETLRKFGMKVFYGDA
                     TRMDLLESAGAAKAEVLINAIDDPQTNLQLTEMVKEHFPHLQIIARARDVDHYIRLRQ
                     AGVEKPERETFEGALKTGRLALESLGLGPYEARERADVFRRFNIQMVEEMAMVENDTK
                     ARAAVYKRTSAMLSEIITEDREHLSLIQRHGWQGTEEGKHTGNMADEPETKPSS"
     misc_feature    47769..49628
                     /gene="kefC"
                     /locus_tag="b0047"
                     /gene_synonym="ECK0048; JW0046; trkC"
                     /note="glutathione-regulated potassium-efflux system
                     protein KefC; Provisional; Region: PRK03562"
                     /db_xref="CDD:235131"
     misc_feature    47805..48623
                     /gene="kefC"
                     /locus_tag="b0047"
                     /gene_synonym="ECK0048; JW0046; trkC"
                     /note="transporter, monovalent cation:proton antiporter-2
                     (CPA2) family; Region: 2a37; TIGR00932"
                     /db_xref="CDD:233195"
     misc_feature    48972..49301
                     /gene="kefC"
                     /locus_tag="b0047"
                     /gene_synonym="ECK0048; JW0046; trkC"
                     /note="TrkA-N domain; Region: TrkA_N; pfam02254"
                     /db_xref="CDD:251184"
     gene            49823..50302
                     /gene="folA"
                     /locus_tag="b0048"
                     /gene_synonym="ECK0049; JW0047; tmrA"
                     /db_xref="EcoGene:EG10326"
                     /db_xref="GeneID:944790"
     CDS             49823..50302
                     /gene="folA"
                     /locus_tag="b0048"
                     /gene_synonym="ECK0049; JW0047; tmrA"
                     /EC_number="1.5.1.3"
                     /function="enzyme; Biosynthesis of cofactors, carriers:
                     Folic acid"
                     /experiment="N-terminus verified by Edman degradation:
                     PMID 350268,4610415"
                     /GO_process="GO:0046656 - folic acid biosynthetic process"
                     /note="dihydrofolate reductase type I; trimethoprim
                     resistance"
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrofolate reductase"
                     /protein_id="NP_414590.1"
                     /db_xref="GI:16128042"
                     /db_xref="ASAP:ABE-0000164"
                     /db_xref="UniProtKB/Swiss-Prot:P0ABQ4"
                     /db_xref="EcoGene:EG10326"
                     /db_xref="GeneID:944790"
                     /translation="MISLIAALAVDRVIGMENAMPWNLPADLAWFKRNTLNKPVIMGR
                     HTWESIGRPLPGRKNIILSSQPGTDDRVTWVKSVDEAIAACGDVPEIMVIGGGRVYEQ
                     FLPKAQKLYLTHIDAEVEGDTHFPDYEPDDWESVFSEFHDADAQNSHSYCFEILERR"
     misc_feature    49826..50293
                     /gene="folA"
                     /locus_tag="b0048"
                     /gene_synonym="ECK0049; JW0047; tmrA"
                     /note="Dihydrofolate reductase (DHFR). Reduces
                     7,8-dihydrofolate to 5,6,7,8-tetrahydrofolate with NADPH
                     as a cofactor. This is an essential step in the
                     biosynthesis of deoxythymidine phosphate since
                     5,6,7,8-tetrahydrofolate is required to regenerate 5;
                     Region: DHFR; cd00209"
                     /db_xref="CDD:238127"
     misc_feature    order(49835..49837,49886..49888,49901..49903,49991..49993,
                     50102..50104,50120..50122,50159..50161)
                     /gene="folA"
                     /locus_tag="b0048"
                     /gene_synonym="ECK0049; JW0047; tmrA"
                     /note="folate binding site [chemical binding]; other site"
                     /db_xref="CDD:238127"
     misc_feature    order(49841..49843,49862..49864,49952..49960,50012..50014,
                     50105..50116)
                     /gene="folA"
                     /locus_tag="b0048"
                     /gene_synonym="ECK0049; JW0047; tmrA"
                     /note="NADP+ binding site [chemical binding]; other site"
                     /db_xref="CDD:238127"
     repeat_region   50327..50363
                     /note="REP5 (repetitive extragenic palindromic) element;
                     contains 1 REP sequences"
     gene            complement(50380..51222)
                     /gene="apaH"
                     /locus_tag="b0049"
                     /gene_synonym="cfcB; ECK0050; JW0048"
                     /db_xref="EcoGene:EG10048"
                     /db_xref="GeneID:944770"
     CDS             complement(50380..51222)
                     /gene="apaH"
                     /locus_tag="b0049"
                     /gene_synonym="cfcB; ECK0050; JW0048"
                     /EC_number="3.6.1.41"
                     /function="enzyme; Salvage of nucleosides and nucleotides"
                     /GO_component="GO:0005737 - cytoplasm"
                     /GO_process="GO:0015949 - nucleobase, nucleoside and
                     nucleotide interconversion"
                     /codon_start=1
                     /transl_table=11
                     /product="diadenosine tetraphosphatase"
                     /protein_id="NP_414591.1"
                     /db_xref="GI:16128043"
                     /db_xref="ASAP:ABE-0000167"
                     /db_xref="UniProtKB/Swiss-Prot:P05637"
                     /db_xref="EcoGene:EG10048"
                     /db_xref="GeneID:944770"
                     /translation="MATYLIGDVHGCYDELIALLHKVEFTPGKDTLWLTGDLVARGPG
                     SLDVLRYVKSLGDSVRLVLGNHDLHLLAVFAGISRNKPKDRLTPLLEAPDADELLNWL
                     RRQPLLQIDEEKKLVMAHAGITPQWDLQTAKECARDVEAVLSSDSYPFFLDAMYGDMP
                     NNWSPELRGLGRLRFITNAFTRMRFCFPNGQLDMYSKESPEEAPAPLKPWFAIPGPVA
                     EEYSIAFGHWASLEGKGTPEGIYALDTGCCWGGTLTCLRWEDKQYFVQPSNRHKDLGE
                     AAAS"
     misc_feature    complement(50386..51222)
                     /gene="apaH"
                     /locus_tag="b0049"
                     /gene_synonym="cfcB; ECK0050; JW0048"
                     /note="bis(5'-nucleosyl)-tetraphosphatase (symmetrical);
                     Region: apaH; TIGR00668"
                     /db_xref="CDD:233082"
     misc_feature    complement(50446..51216)
                     /gene="apaH"
                     /locus_tag="b0049"
                     /gene_synonym="cfcB; ECK0050; JW0048"
                     /note="Escherichia coli ApaH and related proteins,
                     metallophosphatase domain; Region: MPP_ApaH; cd07422"
                     /db_xref="CDD:163665"
     misc_feature    complement(order(50476..50478,50491..50493,50542..50544,
                     50863..50865,51025..51030,51100..51105,51112..51114,
                     51193..51195,51199..51201))
                     /gene="apaH"
                     /locus_tag="b0049"
                     /gene_synonym="cfcB; ECK0050; JW0048"
                     /note="active site"
                     /db_xref="CDD:163665"
     misc_feature    complement(order(50542..50544,50863..50865,51028..51030,
                     51112..51114,51193..51195,51199..51201))
                     /gene="apaH"
                     /locus_tag="b0049"
                     /gene_synonym="cfcB; ECK0050; JW0048"
                     /note="metal binding site [ion binding]; metal-binding
                     site"
                     /db_xref="CDD:163665"
     gene            complement(51229..51606)
                     /gene="apaG"
                     /locus_tag="b0050"
                     /gene_synonym="corD; ECK0051; JW0049; temP"
                     /db_xref="EcoGene:EG10047"
                     /db_xref="GeneID:944772"
     CDS             complement(51229..51606)
                     /gene="apaG"
                     /locus_tag="b0050"
                     /gene_synonym="corD; ECK0051; JW0049; temP"
                     /codon_start=1
                     /transl_table=11
                     /product="protein associated with Co2+ and Mg2+ efflux"
                     /protein_id="NP_414592.1"
                     /db_xref="GI:16128044"
                     /db_xref="ASAP:ABE-0000169"
                     /db_xref="UniProtKB/Swiss-Prot:P62672"
                     /db_xref="EcoGene:EG10047"
                     /db_xref="GeneID:944772"
                     /translation="MINSPRVCIQVQSVYIEAQSSPDNERYVFAYTVTIRNLGRAPVQ
                     LLGRYWLITNGNGRETEVQGEGVVGVQPLIAPGEEYQYTSGAIIETPLGTMQGHYEMI
                     DENGVPFSIDIPVFRLAVPTLIH"
     misc_feature    complement(51232..51606)
                     /gene="apaG"
                     /locus_tag="b0050"
                     /gene_synonym="corD; ECK0051; JW0049; temP"
                     /note="CO2+/MG2+ efflux protein ApaG; Reviewed; Region:
                     apaG; PRK05461"
                     /db_xref="CDD:180098"
     gene            complement(51609..52430)
                     /gene="rsmA"
                     /locus_tag="b0051"
                     /gene_synonym="ECK0052; JW0050; ksgA"
                     /db_xref="EcoGene:EG10523"
                     /db_xref="GeneID:944939"
     CDS             complement(51609..52430)
                     /gene="rsmA"
                     /locus_tag="b0051"
                     /gene_synonym="ECK0052; JW0050; ksgA"
                     /EC_number="2.1.1.-"
                     /function="enzyme; rRNA modification; drug/analog
                     sensitivity"
                     /GO_component="GO:0005737 - cytoplasm"
                     /GO_process="GO:0009451 - RNA modification"
                     /GO_process="GO:0042493 - response to drug"
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA m(6)A1518, m(6)A1519
                     dimethyltransferase, SAM-dependent"
                     /protein_id="NP_414593.1"
                     /db_xref="GI:16128045"
                     /db_xref="ASAP:ABE-0000175"
                     /db_xref="UniProtKB/Swiss-Prot:P06992"
                     /db_xref="EcoGene:EG10523"
                     /db_xref="GeneID:944939"
                     /translation="MNNRVHQGHLARKRFGQNFLNDQFVIDSIVSAINPQKGQAMVEI
                     GPGLAALTEPVGERLDQLTVIELDRDLAARLQTHPFLGPKLTIYQQDAMTFNFGELAE
                     KMGQPLRVFGNLPYNISTPLMFHLFSYTDAIADMHFMLQKEVVNRLVAGPNSKAYGRL
                     SVMAQYYCNVIPVLEVPPSAFTPPPKVDSAVVRLVPHATMPHPVKDVRVLSRITTEAF
                     NQRRKTIRNSLGNLFSVEVLTGMGIDPAMRAENISVAQYCQMANYLAENAPLQES"
     misc_feature    complement(51630..52430)
                     /gene="rsmA"
                     /locus_tag="b0051"
                     /gene_synonym="ECK0052; JW0050; ksgA"
                     /note="16S ribosomal RNA methyltransferase KsgA/Dim1
                     family protein; Reviewed; Region: ksgA; PRK00274"
                     /db_xref="CDD:234708"
     gene            complement(52427..53416)
                     /gene="pdxA"
                     /locus_tag="b0052"
                     /gene_synonym="ECK0053; JW0051"
                     /db_xref="EcoGene:EG10691"
                     /db_xref="GeneID:944919"
     CDS             complement(52427..53416)
                     /gene="pdxA"
                     /locus_tag="b0052"
                     /gene_synonym="ECK0053; JW0051"
                     /EC_number="1.1.1.262"
                     /function="enzyme; Biosynthesis of cofactors, carriers:
                     Pyridoxine"
                     /GO_component="GO:0005737 - cytoplasm"
                     /GO_process="GO:0008615 - pyridoxine biosynthetic process"
                     /note="pyridoxine biosynthesis"
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxy-L-threonine phosphate dehydrogenase,
                     NAD-dependent"
                     /protein_id="NP_414594.1"
                     /db_xref="GI:16128046"
                     /db_xref="ASAP:ABE-0000178"
                     /db_xref="UniProtKB/Swiss-Prot:P19624"
                     /db_xref="EcoGene:EG10691"
                     /db_xref="GeneID:944919"
                     /translation="MVKTQRVVITPGEPAGIGPDLVVQLAQREWPVELVVCADATLLT
                     NRAAMLGLPLTLRPYSPNSPAQPQTAGTLTLLPVALRAPVTAGQLAVENGHYVVETLA
                     RACDGCLNGEFAALITGPVHKGVINDAGIPFTGHTEFFEERSQAKKVVMMLATEELRV
                     ALATTHLPLRDIADAITPALLHEVIAILHHDLRTKFGIAEPRILVCGLNPHAGEGGHM
                     GTEEIDTIIPVLNELRAQGMKLNGPLPADTLFQPKYLDNADAVLAMYHDQGLPVLKYQ
                     GFGRGVNITLGLPFIRTSVDHGTALELAGRGKADVGSFITALNLAIKMIVNTQ"
     misc_feature    complement(52430..53416)
                     /gene="pdxA"
                     /locus_tag="b0052"
                     /gene_synonym="ECK0053; JW0051"
                     /note="4-hydroxythreonine-4-phosphate dehydrogenase;
                     Reviewed; Region: pdxA; PRK00232"
                     /db_xref="CDD:234696"
     gene            complement(53416..54702)
                     /gene="surA"
                     /locus_tag="b0053"
                     /gene_synonym="ECK0054; JW0052"
                     /db_xref="EcoGene:EG10985"
                     /db_xref="GeneID:944812"
     CDS             complement(53416..54702)
                     /gene="surA"
                     /locus_tag="b0053"
                     /gene_synonym="ECK0054; JW0052"
                     /EC_number="5.2.1.8"
                     /function="phenotype; Not classified"
                     /GO_component="GO:0009279 - cell outer membrane"
                     /GO_process="GO:0006457 - protein folding"
                     /note="survival protein"
                     /codon_start=1
                     /transl_table=11
                     /product="peptidyl-prolyl cis-trans isomerase (PPIase)"
                     /protein_id="NP_414595.1"
                     /db_xref="GI:16128047"
                     /db_xref="ASAP:ABE-0000180"
                     /db_xref="UniProtKB/Swiss-Prot:P0ABZ6"
                     /db_xref="EcoGene:EG10985"
                     /db_xref="GeneID:944812"
                     /translation="MKNWKTLLLGIAMIANTSFAAPQVVDKVAAVVNNGVVLESDVDG
                     LMQSVKLNAAQARQQLPDDATLRHQIMERLIMDQIILQMGQKMGVKISDEQLDQAIAN
                     IAKQNNMTLDQMRSRLAYDGLNYNTYRNQIRKEMIISEVRNNEVRRRITILPQEVESL
                     AQQVGNQNDASTELNLSHILIPLPENPTSDQVNEAESQARAIVDQARNGADFGKLAIA
                     HSADQQALNGGQMGWGRIQELPGIFAQALSTAKKGDIVGPIRSGVGFHILKVNDLRGE
                     SKNISVTEVHARHILLKPSPIMTDEQARVKLEQIAADIKSGKTTFAAAAKEFSQDPGS
                     ANQGGDLGWATPDIFDPAFRDALTRLNKGQMSAPVHSSFGWHLIELLDTRNVDKTDAA
                     QKDRAYRMLMNRKFSEEAASWMQEQRASAYVKILSN"
     misc_feature    complement(53419..54648)
                     /gene="surA"
                     /locus_tag="b0053"
                     /gene_synonym="ECK0054; JW0052"
                     /note="peptidyl-prolyl cis-trans isomerase SurA;
                     Provisional; Region: PRK10770"
                     /db_xref="CDD:236758"
     misc_feature    complement(54277..54591)
                     /gene="surA"
                     /locus_tag="b0053"
                     /gene_synonym="ECK0054; JW0052"
                     /note="SurA N-terminal domain; Region: SurA_N; pfam09312"
                     /db_xref="CDD:150092"
     misc_feature    complement(53887..54171)
                     /gene="surA"
                     /locus_tag="b0053"
                     /gene_synonym="ECK0054; JW0052"
                     /note="PPIC-type PPIASE domain; Region: Rotamase;
                     pfam00639"
                     /db_xref="CDD:250020"
     misc_feature    complement(53557..53838)
                     /gene="surA"
                     /locus_tag="b0053"
                     /gene_synonym="ECK0054; JW0052"
                     /note="PPIC-type PPIASE domain; Region: Rotamase;
                     pfam00639"
                     /db_xref="CDD:250020"
     gene            complement(54755..57109)
                     /gene="lptD"
                     /locus_tag="b0054"
                     /gene_synonym="ECK0055; imp; JW0053; ostA; yabG"
                     /db_xref="EcoGene:EG11569"
                     /db_xref="GeneID:945011"
     CDS             complement(54755..57109)
                     /gene="lptD"
                     /locus_tag="b0054"
                     /gene_synonym="ECK0055; imp; JW0053; ostA; yabG"
                     /function="phenotype; Adaptations, atypical conditions"
                     /GO_component="GO:0009274 - peptidoglycan-based cell wall"
                     /GO_component="GO:0019866 - organelle inner membrane"
                     /note="organic solvent tolerance"
                     /codon_start=1
                     /transl_table=11
                     /product="LPS assembly OM complex LptDE, beta-barrel
                     component"
                     /protein_id="NP_414596.1"
                     /db_xref="GI:16128048"
                     /db_xref="ASAP:ABE-0000183"
                     /db_xref="UniProtKB/Swiss-Prot:P31554"
                     /db_xref="EcoGene:EG11569"
                     /db_xref="GeneID:945011"
                     /translation="MKKRIPTLLATMIATALYSQQGLAADLASQCMLGVPSYDRPLVQ
                     GDTNDLPVTINADHAKGDYPDDAVFTGSVDIMQGNSRLQADEVQLHQKEAPGQPEPVR
                     TVDALGNVHYDDNQVILKGPKGWANLNTKDTNVWEGDYQMVGRQGRGKADLMKQRGEN
                     RYTILDNGSFTSCLPGSDTWSVVGSEIIHDREEQVAEIWNARFKVGPVPIFYSPYLQL
                     PVGDKRRSGFLIPNAKYTTTNYFEFYLPYYWNIAPNMDATITPHYMHRRGNIMWENEF
                     RYLSQAGAGLMELDYLPSDKVYEDEHPNDDSSRRWLFYWNHSGVMDQVWRFNVDYTKV
                     SDPSYFNDFDNKYGSSTDGYATQKFSVGYAVQNFNATVSTKQFQVFSEQNTSSYSAEP
                     QLDVNYYQNDVGPFDTRIYGQAVHFVNTRDDMPEATRVHLEPTINLPLSNNWGSINTE
                     AKLLATHYQQTNLDWYNSRNTTKLDESVNRVMPQFKVDGKMVFERDMEMLAPGYTQTL
                     EPRAQYLYVPYRDQSDIYNYDSSLLQSDYSGLFRDRTYGGLDRIASANQVTTGVTSRI
                     YDDAAVERFNISVGQIYYFTESRTGDDNITWENDDKTGSLVWAGDTYWRISERWGLRG
                     GIQYDTRLDNVATSNSSIEYRRDEDRLVQLNYRYASPEYIQATLPKYYSTAEQYKNGI
                     SQVGAVASWPIADRWSIVGAYYYDTNANKQADSMLGVQYSSCCYAIRVGYERKLNGWD
                     NDKQHAVYDNAIGFNIELRGLSSNYGLGTQEMLRSNILPYQNTL"
     misc_feature    complement(54764..57109)
                     /gene="lptD"
                     /locus_tag="b0054"
                     /gene_synonym="ECK0055; imp; JW0053; ostA; yabG"
                     /note="LPS assembly outer membrane complex protein LptD;
                     Provisional; Region: PRK03761"
                     /db_xref="CDD:235158"
     misc_feature    complement(56525..56953)
                     /gene="lptD"
                     /locus_tag="b0054"
                     /gene_synonym="ECK0055; imp; JW0053; ostA; yabG"
                     /note="OstA-like protein; Region: OstA; pfam03968"
                     /db_xref="CDD:252284"
     misc_feature    complement(55019..56182)
                     /gene="lptD"
                     /locus_tag="b0054"
                     /gene_synonym="ECK0055; imp; JW0053; ostA; yabG"
                     /note="Organic solvent tolerance protein; Region: OstA_C;
                     pfam04453"
                     /db_xref="CDD:252606"
     gene            57364..58179
                     /gene="djlA"
                     /locus_tag="b0055"
                     /gene_synonym="ECK0056; JW0054; yabH"
                     /db_xref="EcoGene:EG11570"
                     /db_xref="GeneID:948992"
     CDS             57364..58179
                     /gene="djlA"
                     /locus_tag="b0055"
                     /gene_synonym="ECK0056; JW0054; yabH"
                     /function="factor; Chaperones"
                     /GO_process="GO:0006457 - protein folding"
                     /codon_start=1
                     /transl_table=11
                     /product="membrane-anchored DnaK co-chaperone, DNA-binding
                     protein"
                     /protein_id="NP_414597.1"
                     /db_xref="GI:16128049"
                     /db_xref="ASAP:ABE-0000187"
                     /db_xref="UniProtKB/Swiss-Prot:P31680"
                     /db_xref="EcoGene:EG11570"
                     /db_xref="GeneID:948992"
                     /translation="MQYWGKIIGVAVALLMGGGFWGVVLGLLIGHMFDKARSRKMAWF
                     ANQRERQALFFATTFEVMGHLTKSKGRVTEADIHIASQLMDRMNLHGASRTAAQNAFR
                     VGKSDNYPLREKMRQFRSVCFGRFDLIRMFLEIQIQAAFADGSLHPNERAVLYVIAEE
                     LGISRAQFDQFLRMMQGGAQFGGGYQQQTGGGNWQQAQRGPTLEDACNVLGVKPTDDA
                     TTIKRAYRKLMSEHHPDKLVAKGLPPEMMEMAKQKAQEIQQAYELIKQQKGFK"
     misc_feature    57364..58176
                     /gene="djlA"
                     /locus_tag="b0055"
                     /gene_synonym="ECK0056; JW0054; yabH"
                     /note="Dna-J like membrane chaperone protein; Provisional;
                     Region: djlA; PRK09430"
                     /db_xref="CDD:236512"
     misc_feature    57532..57849
                     /gene="djlA"
                     /locus_tag="b0055"
                     /gene_synonym="ECK0056; JW0054; yabH"
                     /note="N-terminal tellurium resistance protein terB-like
                     domain of heat shock DnaJ-like proteins; Region:
                     terB_like_DjlA; cd07316"
                     /db_xref="CDD:143585"
     misc_feature    order(57568..57570,57589..57591,57790..57792,57811..57813)
                     /gene="djlA"
                     /locus_tag="b0055"
                     /gene_synonym="ECK0056; JW0054; yabH"
                     /note="putative metal binding site [ion binding]; other
                     site"
                     /db_xref="CDD:143585"
     misc_feature    57988..58149
                     /gene="djlA"
                     /locus_tag="b0055"
                     /gene_synonym="ECK0056; JW0054; yabH"
                     /note="DnaJ domain or J-domain.  DnaJ/Hsp40 (heat shock
                     protein 40) proteins are highly conserved and play crucial
                     roles in protein translation, folding, unfolding,
                     translocation, and degradation. They act primarily by
                     stimulating the ATPase activity of Hsp70s; Region: DnaJ;
                     cd06257"
                     /db_xref="CDD:99751"
     misc_feature    order(58060..58068,58114..58116,58123..58128,58135..58140)
                     /gene="djlA"
                     /locus_tag="b0055"
                     /gene_synonym="ECK0056; JW0054; yabH"
                     /note="HSP70 interaction site [polypeptide binding]; other
                     site"
                     /db_xref="CDD:99751"
     gene            58474..59279
                     /gene="yabP"
                     /locus_tag="b4659"
                     /gene_synonym="ECK0057; JW0055; yabQ"
                     /pseudo
                     /db_xref="EcoGene:EG12610"
                     /db_xref="GeneID:944776"
     CDS             join(58474..59052,59052..59279)
                     /gene="yabP"
                     /locus_tag="b4659"
                     /gene_synonym="ECK0057; JW0055; yabQ"
                     /note="pseudogene, pentapeptide repeats-containing"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /db_xref="ASAP:ABE-0000192"
                     /db_xref="ASAP:ABE-0000194"
                     /db_xref="UniProtKB/Swiss-Prot:P39220"
                     /db_xref="EcoGene:EG12610"
                     /db_xref="GeneID:944776"
     gene            complement(59687..60346)
                     /gene="rluA"
                     /locus_tag="b0058"
                     /gene_synonym="ECK0059; JW0057; yabO"
                     /db_xref="EcoGene:EG12609"
                     /db_xref="GeneID:946262"
     CDS             complement(59687..60346)
                     /gene="rluA"
                     /locus_tag="b0058"
                     /gene_synonym="ECK0059; JW0057; yabO"
                     /EC_number="4.2.1.70"
                     /function="enzyme; rRNA modification; tRNA modification"
                     /GO_process="GO:0009451 - RNA modification"
                     /codon_start=1
                     /transl_table=11
                     /product="dual specificity 23S rRNA pseudouridine(746),
                     tRNA pseudouridine(32) synthase, SAM-dependent"
                     /protein_id="NP_414600.1"
                     /db_xref="GI:16128052"
                     /db_xref="ASAP:ABE-0000196"
                     /db_xref="UniProtKB/Swiss-Prot:P0AA37"
                     /db_xref="EcoGene:EG12609"
                     /db_xref="GeneID:946262"
                     /translation="MGMENYNPPQEPWLVILYQDDHIMVVNKPSGLLSVPGRLEEHKD
                     SVMTRIQRDYPQAESVHRLDMATSGVIVVALTKAAERELKRQFREREPKKQYVARVWG
                     HPSPAEGLVDLPLICDWPNRPKQKVCYETGKPAQTEYEVVEYAADNTARVVLKPITGR
                     SHQLRVHMLALGHPILGDRFYASPEARAMAPRLLLHAEMLTITHPAYGNSMTFKAPAD
                     F"
     misc_feature    complement(59690..>60322)
                     /gene="rluA"
                     /locus_tag="b0058"
                     /gene_synonym="ECK0059; JW0057; yabO"
                     /note="Pseudouridylate synthases, 23S RNA-specific
                     [Translation, ribosomal structure and biogenesis]; Region:
                     RluA; COG0564"
                     /db_xref="CDD:223638"
     misc_feature    complement(59741..60280)
                     /gene="rluA"
                     /locus_tag="b0058"
                     /gene_synonym="ECK0059; JW0057; yabO"
                     /note="Pseudouridine synthase, RsuA/RluD family; Region:
                     PseudoU_synth_RluCD_like; cd02869"
                     /db_xref="CDD:211346"
     misc_feature    complement(order(59852..59854,60155..60166))
                     /gene="rluA"
                     /locus_tag="b0058"
                     /gene_synonym="ECK0059; JW0057; yabO"
                     /note="active site"
                     /db_xref="CDD:211346"
     gene            complement(60358..63264)
                     /gene="rapA"
                     /locus_tag="b0059"
                     /gene_synonym="ECK0060; hepA; JW0058; yabA"
                     /db_xref="EcoGene:EG11083"
                     /db_xref="GeneID:948523"
     CDS             complement(60358..63264)
                     /gene="rapA"
                     /locus_tag="b0059"
                     /gene_synonym="ECK0060; hepA; JW0058; yabA"
                     /EC_number="3.6.1.-"
                     /function="putative enzyme; RNA synthesis, modification,
                     DNA transcription"
                     /GO_process="GO:0009451 - RNA modification"
                     /note="probable ATP-dependent RNA helicase"
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase remodeling/recycling factor
                     ATPase; RNA polymerase-associated, ATP-dependent RNA
                     translocase"
                     /protein_id="NP_414601.1"
                     /db_xref="GI:16128053"
                     /db_xref="ASAP:ABE-0000198"
                     /db_xref="UniProtKB/Swiss-Prot:P60240"
                     /db_xref="EcoGene:EG11083"
                     /db_xref="GeneID:948523"
                     /translation="MPFTLGQRWISDTESELGLGTVVAVDARTVTLLFPSTGENRLYA
                     RSDSPVTRVMFNPGDTITSHDGWQMQVEEVKEENGLLTYIGTRLDTEESGVALREVFL
                     DSKLVFSKPQDRLFAGQIDRMDRFALRYRARKYSSEQFRMPYSGLRGQRTSLIPHQLN
                     IAHDVGRRHAPRVLLADEVGLGKTIEAGMILHQQLLSGAAERVLIIVPETLQHQWLVE
                     MLRRFNLRFALFDDERYAEAQHDAYNPFDTEQLVICSLDFARRSKQRLEHLCEAEWDL
                     LVVDEAHHLVWSEDAPSREYQAIEQLAEHVPGVLLLTATPEQLGMESHFARLRLLDPN
                     RFHDFAQFVEEQKNYRPVADAVAMLLAGNKLSNDELNMLGEMIGEQDIEPLLQAANSD
                     SEDAQSARQELVSMLMDRHGTSRVLFRNTRNGVKGFPKRELHTIKLPLPTQYQTAIKV
                     SGIMGARKSAEDRARDMLYPERIYQEFEGDNATWWNFDPRVEWLMGYLTSHRSQKVLV
                     ICAKAATALQLEQVLREREGIRAAVFHEGMSIIERDRAAAWFAEEDTGAQVLLCSEIG
                     SEGRNFQFASHMVMFDLPFNPDLLEQRIGRLDRIGQAHDIQIHVPYLEKTAQSVLVRW
                     YHEGLDAFEHTCPTGRTIYDSVYNDLINYLASPDQTEGFDDLIKNCREQHEALKAQLE
                     QGRDRLLEIHSNGGEKAQALAESIEEQDDDTNLIAFAMNLFDIIGINQDDRGDNMIVL
                     TPSDHMLVPDFPGLSEDGITITFDREVALAREDAQFITWEHPLIRNGLDLILSGDTGS
                     STISLLKNKALPVGTLLVELIYVVEAQAPKQLQLNRFLPPTPVRMLLDKNGNNLAAQV
                     EFETFNRQLNAVNRHTGSKLVNAVQQDVHAILQLGEAQIEKSARALIDAARNEADEKL
                     SAELSRLEALRAVNPNIRDDELTAIESNRQQVMESLDQAGWRLDALRLIVVTHQ"
     misc_feature    complement(60367..63261)
                     /gene="rapA"
                     /locus_tag="b0059"
                     /gene_synonym="ECK0060; hepA; JW0058; yabA"
                     /note="ATP-dependent helicase HepA; Validated; Region:
                     PRK04914"
                     /db_xref="CDD:235319"
     misc_feature    complement(62317..62748)
                     /gene="rapA"
                     /locus_tag="b0059"
                     /gene_synonym="ECK0060; hepA; JW0058; yabA"
                     /note="DEAD-like helicases superfamily. A diverse family
                     of proteins involved in ATP-dependent RNA or DNA
                     unwinding. This domain contains the ATP-binding region;
                     Region: DEXDc; cd00046"
                     /db_xref="CDD:238005"
     misc_feature    complement(62713..62727)
                     /gene="rapA"
                     /locus_tag="b0059"
                     /gene_synonym="ECK0060; hepA; JW0058; yabA"
                     /note="ATP binding site [chemical binding]; other site"
                     /db_xref="CDD:238005"
     misc_feature    complement(62416..62427)
                     /gene="rapA"
                     /locus_tag="b0059"
                     /gene_synonym="ECK0060; hepA; JW0058; yabA"
                     /note="putative Mg++ binding site [ion binding]; other
                     site"
                     /db_xref="CDD:238005"
     misc_feature    complement(61459..61827)
                     /gene="rapA"
                     /locus_tag="b0059"
                     /gene_synonym="ECK0060; hepA; JW0058; yabA"
                     /note="Helicase superfamily c-terminal domain; associated
                     with DEXDc-, DEAD-, and DEAH-box proteins, yeast
                     initiation factor 4A, Ski2p, and Hepatitis C virus NS3
                     helicases; this domain is found in a wide variety of
                     helicases and helicase related proteins; may...; Region:
                     HELICc; cd00079"
                     /db_xref="CDD:238034"
     misc_feature    complement(order(61570..61578,61657..61662,61723..61734))
                     /gene="rapA"
                     /locus_tag="b0059"
                     /gene_synonym="ECK0060; hepA; JW0058; yabA"
                     /note="nucleotide binding region [chemical binding]; other
                     site"
                     /db_xref="CDD:238034"
     misc_feature    complement(order(61468..61470,61477..61479,61489..61491,
                     61552..61554))
                     /gene="rapA"
                     /locus_tag="b0059"
                     /gene_synonym="ECK0060; hepA; JW0058; yabA"
                     /note="ATP-binding site [chemical binding]; other site"
                     /db_xref="CDD:238034"
     misc_feature    complement(60367..61455)
                     /gene="rapA"
                     /locus_tag="b0059"
                     /gene_synonym="ECK0060; hepA; JW0058; yabA"
                     /note="RNA polymerase recycling family C-terminal; Region:
                     RapA_C; pfam12137"
                     /db_xref="CDD:256866"
     gene            complement(63429..65780)
                     /gene="polB"
                     /locus_tag="b0060"
                     /gene_synonym="dinA; ECK0061; JW0059"
                     /db_xref="EcoGene:EG10747"
                     /db_xref="GeneID:944779"
     CDS             complement(63429..65780)
                     /gene="polB"
                     /locus_tag="b0060"
                     /gene_synonym="dinA; ECK0061; JW0059"
                     /EC_number="2.7.7.7"
                     /function="enzyme; DNA - replication, repair,
                     restriction/modification"
                     /GO_component="GO:0005737 - cytoplasm"
                     /GO_process="GO:0006261 - DNA-dependent DNA replication"
                     /GO_process="GO:0006281 - DNA repair"
                     /GO_process="GO:0009314 - response to radiation"
                     /GO_process="GO:0009432 - SOS response"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase II"
                     /protein_id="NP_414602.1"
                     /db_xref="GI:16128054"
                     /db_xref="ASAP:ABE-0000202"
                     /db_xref="UniProtKB/Swiss-Prot:P21189"
                     /db_xref="EcoGene:EG10747"
                     /db_xref="GeneID:944779"
                     /translation="MAQAGFILTRHWRDTPQGTEVSFWLATDNGPLQVTLAPQESVAF
                     IPADQVPRAQHILQGEQGFRLTPLALKDFHRQPVYGLYCRAHRQLMNYEKRLREGGVT
                     VYEADVRPPERYLMERFITSPVWVEGDMHNGTIVNARLKPHPDYRPPLKWVSIDIETT
                     RHGELYCIGLEGCGQRIVYMLGPENGDASSLDFELEYVASRPQLLEKLNAWFANYDPD
                     VIIGWNVVQFDLRMLQKHAERYRLPLRLGRDNSELEWREHGFKNGVFFAQAKGRLIID
                     GIEALKSAFWNFSSFSLETVAQELLGEGKSIDNPWDRMDEIDRRFAEDKPALATYNLK
                     DCELVTQIFHKTEIMPFLLERATVNGLPVDRHGGSVAAFGHLYFPRMHRAGYVAPNLG
                     EVPPHASPGGYVMDSRPGLYDSVLVLDYKSLYPSIIRTFLIDPVGLVEGMAQPDPEHS
                     TEGFLDAWFSREKHCLPEIVTNIWHGRDEAKRQGNKPLSQALKIIMNAFYGVLGTTAC
                     RFFDPRLASSITMRGHQIMRQTKALIEAQGYDVIYGDTDSTFVWLKGAHSEEEAAKIG
                     RALVQHVNAWWAETLQKQRLTSALELEYETHFCRFLMPTIRGADTGSKKRYAGLIQEG
                     DKQRMVFKGLETVRTDWTPLAQQFQQELYLRIFRNEPYQEYVRETIDKLMAGELDARL
                     VYRKRLRRPLSEYQRNVPPHVRAARLADEENQKRGRPLQYQNRGTIKYVWTTNGPEPL
                     DYQRSPLDYEHYLTRQLQPVAEGILPFIEDNFATLMTGQLGLF"
     misc_feature    complement(63432..65780)
                     /gene="polB"
                     /locus_tag="b0060"
                     /gene_synonym="dinA; ECK0061; JW0059"
                     /note="DNA polymerase II; Reviewed; Region: PRK05762"
                     /db_xref="CDD:235595"
     misc_feature    complement(64749..65339)
                     /gene="polB"
                     /locus_tag="b0060"
                     /gene_synonym="dinA; ECK0061; JW0059"
                     /note="DEDDy 3'-5' exonuclease domain of Escherichia coli
                     DNA polymerase II and similar bacterial family-B DNA
                     polymerases; Region: DNA_polB_II_exo; cd05784"
                     /db_xref="CDD:99827"
     misc_feature    complement(order(64776..64778,64788..64790,64902..64907,
                     65094..65102,65109..65114,65304..65315))
                     /gene="polB"
                     /locus_tag="b0060"
                     /gene_synonym="dinA; ECK0061; JW0059"
                     /note="active site"
                     /db_xref="CDD:99827"
     misc_feature    complement(order(64776..64778,64788..64790,65094..65096,
                     65307..65309,65313..65315))
                     /gene="polB"
                     /locus_tag="b0060"
                     /gene_synonym="dinA; ECK0061; JW0059"
                     /note="catalytic site [active]"
                     /db_xref="CDD:99827"
     misc_feature    complement(order(64776..64778,64788..64790,64902..64907,
                     65097..65102,65109..65114,65304..65312))
                     /gene="polB"
                     /locus_tag="b0060"
                     /gene_synonym="dinA; ECK0061; JW0059"
                     /note="substrate binding site [chemical binding]; other
                     site"
                     /db_xref="CDD:99827"
     misc_feature    complement(63474..64592)
                     /gene="polB"
                     /locus_tag="b0060"
                     /gene_synonym="dinA; ECK0061; JW0059"
                     /note="DNA polymerase type-II subfamily catalytic domain.
                     Bacteria contain five DNA polymerases (I, II, III, IV and
                     V). DNA polymerase II (Pol II) is a prototype for the
                     B-family of polymerases. The role of Pol II in a variety
                     of cellular activities, such as...; Region: POLBc_Pol_II;
                     cd05537"
                     /db_xref="CDD:99920"
     misc_feature    complement(order(64140..64142,64290..64292,64302..64304,
                     64350..64352,64509..64517,64524..64526))
                     /gene="polB"
                     /locus_tag="b0060"
                     /gene_synonym="dinA; ECK0061; JW0059"
                     /note="active site"
                     /db_xref="CDD:99920"
     misc_feature    complement(order(64140..64142,64146..64148))
                     /gene="polB"
                     /locus_tag="b0060"
                     /gene_synonym="dinA; ECK0061; JW0059"
                     /note="metal-binding site"
                     /db_xref="CDD:99920"
     gene            complement(65855..66550)
                     /gene="araD"
                     /locus_tag="b0061"
                     /gene_synonym="ECK0062; JW0060"
                     /db_xref="EcoGene:EG10055"
                     /db_xref="GeneID:945294"
     CDS             complement(65855..66550)
                     /gene="araD"
                     /locus_tag="b0061"
                     /gene_synonym="ECK0062; JW0060"
                     /EC_number="5.1.3.4"
                     /function="enzyme; Degradation of small molecules: Carbon
                     compounds"
                     /experiment="N-terminus verified by Edman degradation:
                     PMID 3549454,8520491"
                     /GO_component="GO:0005737 - cytoplasm"
                     /GO_process="GO:0016052 - carbohydrate catabolic process"
                     /codon_start=1
                     /transl_table=11
                     /product="L-ribulose-5-phosphate 4-epimerase"
                     /protein_id="NP_414603.1"
                     /db_xref="GI:16128055"
                     /db_xref="ASAP:ABE-0000209"
                     /db_xref="UniProtKB/Swiss-Prot:P08203"
                     /db_xref="EcoGene:EG10055"
                     /db_xref="GeneID:945294"
                     /translation="MLEDLKRQVLEANLALPKHNLVTLTWGNVSAVDRERGVFVIKPS
                     GVDYSVMTADDMVVVSIETGEVVEGTKKPSSDTPTHRLLYQAFPSIGGIVHTHSRHAT
                     IWAQAGQSIPATGTTHADYFYGTIPCTRKMTDAEINGEYEWETGNVIVETFEKQGIDA
                     AQMPGVLVHSHGPFAWGKNAEDAVHNAIVLEEVAYMGIFCRQLAPQLPDMQQTLLDKH
                     YLRKHGAKAYYGQ"
     misc_feature    complement(65882..66544)
                     /gene="araD"
                     /locus_tag="b0061"
                     /gene_synonym="ECK0062; JW0060"
                     /note="Class II Aldolase and Adducin head (N-terminal)
                     domain. Aldolases are ubiquitous enzymes catalyzing
                     central steps of carbohydrate metabolism. Based on
                     enzymatic mechanisms, this superfamily has been divided
                     into two distinct classes (Class I and II); Region:
                     Aldolase_II; cd00398"
                     /db_xref="CDD:238232"
     misc_feature    complement(order(65894..65896,65954..65956,65975..65977,
                     65987..65989,66008..66010,66041..66043,66158..66160,
                     66200..66205,66209..66211,66230..66238,66251..66256,
                     66260..66262,66401..66406,66410..66412,66482..66484,
                     66506..66508,66518..66520))
                     /gene="araD"
                     /locus_tag="b0061"
                     /gene_synonym="ECK0062; JW0060"
                     /note="intersubunit interface [polypeptide binding]; other
                     site"
                     /db_xref="CDD:238232"
     misc_feature    complement(order(66038..66040,66260..66262,66266..66268,
                     66323..66331,66416..66421,66467..66469))
                     /gene="araD"
                     /locus_tag="b0061"
                     /gene_synonym="ECK0062; JW0060"
                     /note="active site"
                     /db_xref="CDD:238232"
     misc_feature    complement(order(66038..66040,66260..66262,66266..66268))
                     /gene="araD"
                     /locus_tag="b0061"
                     /gene_synonym="ECK0062; JW0060"
                     /note="Zn2+ binding site [ion binding]; other site"
                     /db_xref="CDD:238232"
     repeat_region   66565..66812
                     /note="REP6 (repetitive extragenic palindromic) element;
                     contains 6 REP sequences"
     gene            complement(66835..68337)
                     /gene="araA"
                     /locus_tag="b0062"
                     /gene_synonym="ECK0063; JW0061"
                     /db_xref="EcoGene:EG10052"
                     /db_xref="GeneID:947511"
     CDS             complement(66835..68337)
                     /gene="araA"
                     /locus_tag="b0062"
                     /gene_synonym="ECK0063; JW0061"
                     /EC_number="5.3.1.4"
                     /function="enzyme; Degradation of small molecules: Carbon
                     compounds"
                     /experiment="N-terminus verified by Edman degradation:
                     PMID 3549454"
                     /GO_component="GO:0005737 - cytoplasm"
                     /GO_process="GO:0016052 - carbohydrate catabolic process"
                     /codon_start=1
                     /transl_table=11
                     /product="L-arabinose isomerase"
                     /protein_id="NP_414604.1"
                     /db_xref="GI:16128056"
                     /db_xref="ASAP:ABE-0000221"
                     /db_xref="UniProtKB/Swiss-Prot:P08202"
                     /db_xref="EcoGene:EG10052"
                     /db_xref="GeneID:947511"
                     /translation="MTIFDNYEVWFVIGSQHLYGPETLRQVTQHAEHVVNALNTEAKL
                     PCKLVLKPLGTTPDEITAICRDANYDDRCAGLVVWLHTFSPAKMWINGLTMLNKPLLQ
                     FHTQFNAALPWDSIDMDFMNLNQTAHGGREFGFIGARMRQQHAVVTGHWQDKQAHERI
                     GSWMRQAVSKQDTRHLKVCRFGDNMREVAVTDGDKVAAQIKFGFSVNTWAVGDLVQVV
                     NSISDGDVNALVDEYESCYTMTPATQIHGKKRQNVLEAARIELGMKRFLEQGGFHAFT
                     TTFEDLHGLKQLPGLAVQRLMQQGYGFAGEGDWKTAALLRIMKVMSTGLQGGTSFMED
                     YTYHFEKGNDLVLGSHMLEVCPSIAAEEKPILDVQHLGIGGKDDPARLIFNTQTGPAI
                     VASLIDLGDRYRLLVNCIDTVKTPHSLPKLPVANALWKAQPDLPTASEAWILAGGAHH
                     TVFSHALNLNDMRQFAEMHDIEITVIDNDTRLPAFKDALRWNEVYYGFRR"
     misc_feature    complement(66838..68337)
                     /gene="araA"
                     /locus_tag="b0062"
                     /gene_synonym="ECK0063; JW0061"
                     /note="L-arabinose isomerase; Provisional; Region:
                     PRK02929"
                     /db_xref="CDD:179503"
     misc_feature    complement(66865..68319)
                     /gene="araA"
                     /locus_tag="b0062"
                     /gene_synonym="ECK0063; JW0061"
                     /note="L-Arabinose isomerase (AI) catalyzes the
                     isomerization of L-arabinose to L-ribulose, the first
                     reaction in its conversion into D-xylulose-5-phosphate, an
                     intermediate in the pentose phosphate pathway, which
                     allows L-arabinose to be used as a carbon...; Region:
                     L-arabinose_isomerase; cd03557"
                     /db_xref="CDD:239619"
     misc_feature    complement(order(67495..67500,67525..67527,67690..67692,
                     67702..67722,67741..67743,67750..67752,67786..67788,
                     67807..67809,67915..67920,68074..68076,68134..68136,
                     68143..68145,68155..68157))
                     /gene="araA"
                     /locus_tag="b0062"
                     /gene_synonym="ECK0063; JW0061"
                     /note="putative hexamer (dimer of trimers) interface
                     [polypeptide binding]; other site"
                     /db_xref="CDD:239619"
     misc_feature    complement(order(66865..66870,66937..66939,66991..66993,
                     67000..67002,67009..67011,67018..67023,67066..67068,
                     67072..67077,67081..67083,67138..67146,67321..67338,
                     67768..67779,67861..67863,67894..67896,67900..67902,
                     67915..67917,67921..67926,67933..67935,67942..67947,
                     67954..67959,67975..67977,67984..67992,67999..68001,
                     68005..68007,68011..68013,68020..68022,68026..68028,
                     68074..68085,68089..68091))
                     /gene="araA"
                     /locus_tag="b0062"
                     /gene_synonym="ECK0063; JW0061"
                     /note="trimer interface [polypeptide binding]; other site"
                     /db_xref="CDD:239619"
     misc_feature    complement(order(66988..66993,67339..67341,67420..67422,
                     67501..67503,68089..68091))
                     /gene="araA"
                     /locus_tag="b0062"
                     /gene_synonym="ECK0063; JW0061"
                     /note="putative substrate binding site [chemical binding];
                     other site"
                     /db_xref="CDD:239619"
     misc_feature    complement(order(66988..66990,67339..67341,67420..67422))
                     /gene="araA"
                     /locus_tag="b0062"
                     /gene_synonym="ECK0063; JW0061"
                     /note="putative metal binding site [ion binding]; other
                     site"
                     /db_xref="CDD:239619"
     gene            complement(68348..70048)
                     /gene="araB"
                     /locus_tag="b0063"
                     /gene_synonym="ECK0064; JW0062"
                     /db_xref="EcoGene:EG10053"
                     /db_xref="GeneID:946017"
     CDS             complement(68348..70048)
                     /gene="araB"
                     /locus_tag="b0063"
                     /gene_synonym="ECK0064; JW0062"
                     /EC_number="2.7.1.16"
                     /function="enzyme; Degradation of small molecules: Carbon
                     compounds"
                     /GO_component="GO:0005737 - cytoplasm"
                     /GO_process="GO:0016052 - carbohydrate catabolic process"
                     /codon_start=1
                     /transl_table=11
                     /product="L-ribulokinase"
                     /protein_id="NP_414605.1"
                     /db_xref="GI:16128057"
                     /db_xref="ASAP:ABE-0000223"
                     /db_xref="UniProtKB/Swiss-Prot:P08204"
                     /db_xref="EcoGene:EG10053"
                     /db_xref="GeneID:946017"
                     /translation="MAIAIGLDFGSDSVRALAVDCATGEEIATSVEWYPRWQKGQFCD
                     APNNQFRHHPRDYIESMEAALKTVLAELSVEQRAAVVGIGVDSTGSTPAPIDADGNVL
                     ALRPEFAENPNAMFVLWKDHTAVEEAEEITRLCHAPGNVDYSRYIGGIYSSEWFWAKI
                     LHVTRQDSAVAQSAASWIELCDWVPALLSGTTRPQDIRRGRCSAGHKSLWHESWGGLP
                     PASFFDELDPILNRHLPSPLFTDTWTADIPVGTLCPEWAQRLGLPESVVISGGAFDCH
                     MGAVGAGAQPNALVKVIGTSTCDILIADKQSVGERAVKGICGQVDGSVVPGFIGLEAG
                     QSAFGDIYAWFGRVLGWPLEQLAAQHPELKTQINASQKQLLPALTEAWAKNPSLDHLP
                     VVLDWFNGRRTPNANQRLKGVITDLNLATDAPLLFGGLIAATAFGARAIMECFTDQGI
                     AVNNVMALGGIARKNQVIMQACCDVLNRPLQIVASDQCCALGAAIFAAVAAKVHADIP
                     SAQQKMASAVEKTLQPCSEQAQRFEQLYRRYQQWAMSAEQHYLPTSAPAQAAQAVATL
                     "
     misc_feature    complement(68390..70048)
                     /gene="araB"
                     /locus_tag="b0063"
                     /gene_synonym="ECK0064; JW0062"
                     /note="ribulokinase; Provisional; Region: PRK04123"
                     /db_xref="CDD:235221"
     misc_feature    complement(68507..70045)
                     /gene="araB"
                     /locus_tag="b0063"
                     /gene_synonym="ECK0064; JW0062"
                     /note="Ribulokinases; belongs to the FGGY family of
                     carbohydrate kinases; Region: FGGY_RBK; cd07781"
                     /db_xref="CDD:198358"
     misc_feature    complement(order(68507..68512,68546..68563,68567..68572,
                     68576..68584,68588..68590,68831..68833,68843..68845,
                     69053..69061,69071..69073,69077..69103,69110..69112,
                     69116..69118,69206..69214,69218..69220,69242..69244,
                     69248..69250,69305..69319,69413..69421,69431..69436,
                     69443..69448,69584..69586,69599..69601,69605..69616,
                     69791..69808,69962..69964,69974..69979,69992..69994,
                     69998..70000,70004..70006,70025..70027,70031..70033,
                     70037..70039))
                     /gene="araB"
                     /locus_tag="b0063"
                     /gene_synonym="ECK0064; JW0062"
                     /note="N- and C-terminal domain interface [polypeptide
                     binding]; other site"
                     /db_xref="CDD:198358"
     misc_feature    complement(order(68582..68584,68654..68656,68666..68674,
                     68915..68917,69020..69022,69032..69034,69155..69157,
                     69164..69172,69224..69229,69692..69694,69779..69781,
                     69785..69787,70004..70006,70010..70021,70025..70027))
                     /gene="araB"
                     /locus_tag="b0063"
                     /gene_synonym="ECK0064; JW0062"
                     /note="active site"
                     /db_xref="CDD:198358"
     misc_feature    complement(order(68654..68656,68666..68674,68906..68908,
                     68912..68917,69020..69025,69029..69034,69164..69172,
                     69227..69229,70004..70006,70010..70021,70025..70027))
                     /gene="araB"
                     /locus_tag="b0063"
                     /gene_synonym="ECK0064; JW0062"
                     /note="MgATP binding site [chemical binding]; other site"
                     /db_xref="CDD:198358"
     misc_feature    complement(order(69227..69229,70016..70018,70025..70027))
                     /gene="araB"
                     /locus_tag="b0063"
                     /gene_synonym="ECK0064; JW0062"
                     /note="catalytic site [active]"
                     /db_xref="CDD:198358"
     misc_feature    complement(order(69227..69229,70025..70027))
                     /gene="araB"
                     /locus_tag="b0063"
                     /gene_synonym="ECK0064; JW0062"
                     /note="metal binding site [ion binding]; metal-binding
                     site"
                     /db_xref="CDD:198358"
     misc_feature    complement(order(69053..69055,69155..69157,69164..69166,
                     69224..69229,69428..69430,69587..69589,69692..69694,
                     69779..69787,70016..70021))
                     /gene="araB"
                     /locus_tag="b0063"
                     /gene_synonym="ECK0064; JW0062"
                     /note="carbohydrate binding site [chemical binding]; other
                     site"
                     /db_xref="CDD:198358"
     misc_feature    complement(order(68780..68788,68792..68818,68852..68857,
                     68870..68872,68876..68878,68993..69010,69017..69019,
                     69029..69031))
                     /gene="araB"
                     /locus_tag="b0063"
                     /gene_synonym="ECK0064; JW0062"
                     /note="homodimer interface [polypeptide binding]; other
                     site"
                     /db_xref="CDD:198358"
     gene            70387..71265
                     /gene="araC"
                     /locus_tag="b0064"
                     /gene_synonym="ECK0065; JW0063"
                     /db_xref="EcoGene:EG10054"
                     /db_xref="GeneID:944780"
     CDS             70387..71265
                     /gene="araC"
                     /locus_tag="b0064"
                     /gene_synonym="ECK0065; JW0063"
                     /function="regulator; Degradation of small molecules:
                     Carbon compounds"
                     /GO_component="GO:0005737 - cytoplasm"
                     /GO_function="GO:0016563 - transcription activator
                     activity"
                     /GO_function="GO:0016564 - transcription repressor
                     activity"
                     /GO_process="GO:0016052 - carbohydrate catabolic process"
                     /GO_process="GO:0006350 - transcription"
                     /note="transcriptional regulator for ara operon"
                     /codon_start=1
                     /transl_table=11
                     /product="ara regulon transcriptional activator;
                     autorepressor"
                     /protein_id="NP_414606.1"
                     /db_xref="GI:16128058"
                     /db_xref="ASAP:ABE-0000236"
                     /db_xref="UniProtKB/Swiss-Prot:P0A9E0"
                     /db_xref="EcoGene:EG10054"
                     /db_xref="GeneID:944780"
                     /translation="MAEAQNDPLLPGYSFNAHLVAGLTPIEANGYLDFFIDRPLGMKG
                     YILNLTIRGQGVVKNQGREFVCRPGDILLFPPGEIHHYGRHPEAREWYHQWVYFRPRA
                     YWHEWLNWPSIFANTGFFRPDEAHQPHFSDLFGQIINAGQGEGRYSELLAINLLEQLL
                     LRRMEAINESLHPPMDNRVREACQYISDHLADSNFDIASVAQHVCLSPSRLSHLFRQQ
                     LGISVLSWREDQRISQAKLLLSTTRMPIATVGRNVGFDDQLYFSRVFKKCTGASPSEF
                     RAGCEEKVNDVAVKLS"
     misc_feature    70387..71241
                     /gene="araC"
                     /locus_tag="b0064"
                     /gene_synonym="ECK0065; JW0063"
                     /note="DNA-binding transcriptional regulator AraC;
                     Provisional; Region: PRK10572"
                     /db_xref="CDD:236717"
     misc_feature    70447..70854
                     /gene="araC"
                     /locus_tag="b0064"
                     /gene_synonym="ECK0065; JW0063"
                     /note="AraC-like ligand binding domain; Region:
                     AraC_binding; pfam02311"
                     /db_xref="CDD:145456"
     misc_feature    70942..71067
                     /gene="araC"
                     /locus_tag="b0064"
                     /gene_synonym="ECK0065; JW0063"
                     /note="Bacterial regulatory helix-turn-helix proteins,
                     AraC family; Region: HTH_AraC; pfam00165"
                     /db_xref="CDD:249644"
     misc_feature    71107..71217
                     /gene="araC"
                     /locus_tag="b0064"
                     /gene_synonym="ECK0065; JW0063"
                     /note="Bacterial regulatory helix-turn-helix proteins,
                     AraC family; Region: HTH_AraC; pfam00165"
                     /db_xref="CDD:249644"
     gene            71351..72115
                     /gene="yabI"
                     /locus_tag="b0065"
                     /gene_synonym="ECK0066; JW5005"
                     /db_xref="EcoGene:EG11571"
                     /db_xref="GeneID:944783"
     CDS             71351..72115
                     /gene="yabI"
                     /locus_tag="b0065"
                     /gene_synonym="ECK0066; JW5005"
                     /GO_component="GO:0009274 - peptidoglycan-based cell wall"
                     /codon_start=1
                     /transl_table=11
                     /product="DedA family inner membrane protein"
                     /protein_id="NP_414607.1"
                     /db_xref="GI:16128059"
                     /db_xref="ASAP:ABE-0000241"
                     /db_xref="UniProtKB/Swiss-Prot:P30149"
                     /db_xref="EcoGene:EG11571"
                     /db_xref="GeneID:944783"
                     /translation="MQALLEHFITQSTVYSLMAVVLVAFLESLALVGLILPGTVLMAG
                     LGALIGSGELSFWHAWLAGIIGCLMGDWISFWLGWRFKKPLHRWSFLKKNKALLDKTE
                     HALHQHSMFTILVGRFVGPTRPLVPMVAGMLDLPVAKFITPNIIGCLLWPPFYFLPGI
                     LAGAAIDIPAGMQSGEFKWLLLATAVFLWVGGWLCWRLWRSGKATDRLSHYLSRGRLL
                     WLTPLISAIGVVALVVLIRHPLMPVYIDILRKVVGV"
     misc_feature    71372..71968
                     /gene="yabI"
                     /locus_tag="b0065"
                     /gene_synonym="ECK0066; JW5005"
                     /note="Uncharacterized membrane-associated protein
                     [Function unknown]; Region: DedA; COG0586"
                     /db_xref="CDD:223659"
     repeat_region   72136..72220
                     /note="REP7 (repetitive extragenic palindromic) element;
                     contains 2 REP sequences"
     gene            complement(72229..72927)
                     /gene="thiQ"
                     /locus_tag="b0066"
                     /gene_synonym="ECK0067; JW0065; sfuC; yabJ"
                     /db_xref="EcoGene:EG11572"
                     /db_xref="GeneID:944785"
     CDS             complement(72229..72927)
                     /gene="thiQ"
                     /locus_tag="b0066"
                     /gene_synonym="ECK0067; JW0065; sfuC; yabJ"
                     /function="transport; Transport of small molecules: Other"
                     /GO_component="GO:0009274 - peptidoglycan-based cell wall"
                     /GO_component="GO:0005737 - cytoplasm"
                     /GO_process="GO:0009228 - thiamin biosynthetic process"
                     /note="putative ATP-binding component of a transport
                     system"
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine/thiamine pyrophosphate ABC transporter
                     ATPase"
                     /protein_id="NP_414608.1"
                     /db_xref="GI:16128060"
                     /db_xref="ASAP:ABE-0000244"
                     /db_xref="UniProtKB/Swiss-Prot:P31548"
                     /db_xref="EcoGene:EG11572"
                     /db_xref="GeneID:944785"
                     /translation="MLKLTDITWLYHHLPMRFSLTVERGEQVAILGPSGAGKSTLLNL
                     IAGFLTPASGSLTIDGVDHTTMPPSRRPVSMLFQENNLFSHLTVAQNIGLGLNPGLKL
                     NAVQQGKMHAIARQMGIDNLMARLPGELSGGQRQRVALARCLVREQPILLLDEPFSAL
                     DPALRQEMLTLVSTSCQQQKMTLLMVSHSVEDAARIATRSVVVADGRIAWQGMTNELL
                     SGKASASALLGITG"
     misc_feature    complement(72235..72927)
                     /gene="thiQ"
                     /locus_tag="b0066"
                     /gene_synonym="ECK0067; JW0065; sfuC; yabJ"
                     /note="thiamine transporter ATP-binding subunit;
                     Provisional; Region: thiQ; PRK10771"
                     /db_xref="CDD:182716"
     misc_feature    complement(72292..72924)
                     /gene="thiQ"
                     /locus_tag="b0066"
                     /gene_synonym="ECK0067; JW0065; sfuC; yabJ"
                     /note="ATP-binding cassette domain of the thiamine
                     transport system; Region: ABC_ThiQ_thiamine_transporter;
                     cd03298"
                     /db_xref="CDD:213265"
     misc_feature    complement(72811..72834)
                     /gene="thiQ"
                     /locus_tag="b0066"
                     /gene_synonym="ECK0067; JW0065; sfuC; yabJ"
                     /note="Walker A/P-loop; other site"
                     /db_xref="CDD:213265"
     misc_feature    complement(order(72364..72366,72463..72468,72694..72696,
                     72808..72816,72820..72825))
                     /gene="thiQ"
                     /locus_tag="b0066"
                     /gene_synonym="ECK0067; JW0065; sfuC; yabJ"
                     /note="ATP binding site [chemical binding]; other site"
                     /db_xref="CDD:213265"
     misc_feature    complement(72694..72705)
                     /gene="thiQ"
                     /locus_tag="b0066"
                     /gene_synonym="ECK0067; JW0065; sfuC; yabJ"
                     /note="Q-loop/lid; other site"
                     /db_xref="CDD:213265"
     misc_feature    complement(72511..72540)
                     /gene="thiQ"
                     /locus_tag="b0066"
                     /gene_synonym="ECK0067; JW0065; sfuC; yabJ"
                     /note="ABC transporter signature motif; other site"
                     /db_xref="CDD:213265"
     misc_feature    complement(72463..72480)
                     /gene="thiQ"
                     /locus_tag="b0066"
                     /gene_synonym="ECK0067; JW0065; sfuC; yabJ"
                     /note="Walker B; other site"
                     /db_xref="CDD:213265"
     misc_feature    complement(72445..72456)
                     /gene="thiQ"
                     /locus_tag="b0066"
                     /gene_synonym="ECK0067; JW0065; sfuC; yabJ"
                     /note="D-loop; other site"
                     /db_xref="CDD:213265"
     misc_feature    complement(72358..72378)
                     /gene="thiQ"
                     /locus_tag="b0066"
                     /gene_synonym="ECK0067; JW0065; sfuC; yabJ"
                     /note="H-loop/switch region; other site"
                     /db_xref="CDD:213265"
     gene            complement(72911..74521)
                     /gene="thiP"
                     /locus_tag="b0067"
                     /gene_synonym="ECK0068; JW0066; sfuB; yabK"
                     /db_xref="EcoGene:EG11573"
                     /db_xref="GeneID:944784"
     CDS             complement(72911..74521)
                     /gene="thiP"
                     /locus_tag="b0067"
                     /gene_synonym="ECK0068; JW0066; sfuB; yabK"
                     /GO_component="GO:0009274 - peptidoglycan-based cell wall"
                     /GO_component="GO:0019866 - organelle inner membrane"
                     /GO_process="GO:0009228 - thiamin biosynthetic process"
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine/thiamine pyrophosphate ABC transporter
                     permease"
                     /protein_id="NP_414609.1"
                     /db_xref="GI:16128061"
                     /db_xref="ASAP:ABE-0000246"
                     /db_xref="UniProtKB/Swiss-Prot:P31549"
                     /db_xref="EcoGene:EG11573"
                     /db_xref="GeneID:944784"
                     /translation="MATRRQPLIPGWLIPGVSATTLVVAVALAAFLALWWNAPQDDWV
                     AVWQDSYLWHVVRFSFWQAFLSALLSVIPAIFLARALYRRRFPGRLALLRLCAMTLIL
                     PVLVAVFGILSVYGRQGWLATLCQSLGLEWTFSPYGLQGILLAHVFFNLPMASRLLLQ
                     ALENIPGEQRQLAAQLGMRSWHFFRFVEWPWLRRQIPPVAALIFMLCFASFATVLSLG
                     GGPQATTIELAIYQALSYDYDPARAAMLALLQMVCCLGLVLLSQRLSKAIAPGTTLLQ
                     GWRDPDDRLHSRICDTVLIVLALLLLLPPLLAVIVDGVNRQLPEVLAQPVLWQALWTS
                     LRIALAAGVLCVVLTMMLLWSSRELRARQKMLAGQVLEMSGMLILAMPGIVLATGFFL
                     LLNNTIGLPQSADGIVIFTNALMAIPYALKVLENPMRDITARYSMLCQSLGIEGWSRL
                     KVVELRALKRPLAQALAFACVLSIGDFGVVALFGNDDFRTLPFYLYQQIGSYRSQDGA
                     VTALILLLLCFLLFTVIEKLPGRNVKTD"
     misc_feature    complement(72917..74491)
                     /gene="thiP"
                     /locus_tag="b0067"
                     /gene_synonym="ECK0068; JW0066; sfuB; yabK"
                     /note="thiamine transporter membrane protein; Reviewed;
                     Region: thiP; PRK09433"
                     /db_xref="CDD:181853"
     misc_feature    complement(73757..74353)
                     /gene="thiP"
                     /locus_tag="b0067"
                     /gene_synonym="ECK0068; JW0066; sfuB; yabK"
                     /note="Transmembrane subunit (TM) found in Periplasmic
                     Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC)
                     transporters which generally bind type 2 PBPs. These types
                     of transporters consist of a PBP, two TMs, and two
                     cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2;
                     cd06261"
                     /db_xref="CDD:119394"
     misc_feature    complement(order(73757..73762,73769..73774,73781..73786,
                     73790..73795,73802..73807,73835..73840,73874..73879,
                     73886..73897,73916..73918,73925..73930,73970..73972,
                     74021..74023,74030..74035,74045..74047,74051..74056,
                     74063..74065,74069..74071,74078..74083,74186..74188,
                     74192..74197,74204..74233,74237..74248,74276..74278,
                     74291..74296,74303..74308))
                     /gene="thiP"
                     /locus_tag="b0067"
                     /gene_synonym="ECK0068; JW0066; sfuB; yabK"
                     /note="dimer interface [polypeptide binding]; other site"
                     /db_xref="CDD:119394"
     misc_feature    complement(order(73880..73897,74186..74230))
                     /gene="thiP"
                     /locus_tag="b0067"
                     /gene_synonym="ECK0068; JW0066; sfuB; yabK"
                     /note="conserved gate region; other site"
                     /db_xref="CDD:119394"
     misc_feature    complement(order(73805..73807,73835..73837,73844..73846,
                     73877..73879,74096..74098,74186..74188))
                     /gene="thiP"
                     /locus_tag="b0067"
                     /gene_synonym="ECK0068; JW0066; sfuB; yabK"
                     /note="putative PBP binding loops; other site"
                     /db_xref="CDD:119394"
     misc_feature    complement(order(73949..73951,73961..73966,73982..74020))
                     /gene="thiP"
                     /locus_tag="b0067"
                     /gene_synonym="ECK0068; JW0066; sfuB; yabK"
                     /note="ABC-ATPase subunit interface; other site"
                     /db_xref="CDD:119394"
     misc_feature    complement(72989..73531)
                     /gene="thiP"
                     /locus_tag="b0067"
                     /gene_synonym="ECK0068; JW0066; sfuB; yabK"
                     /note="Transmembrane subunit (TM) found in Periplasmic
                     Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC)
                     transporters which generally bind type 2 PBPs. These types
                     of transporters consist of a PBP, two TMs, and two
                     cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2;
                     cd06261"
                     /db_xref="CDD:119394"
     misc_feature    complement(order(72989..72994,73001..73006,73034..73039,
                     73076..73081,73088..73099,73118..73120,73127..73132,
                     73172..73174,73223..73225,73232..73237,73247..73249,
                     73253..73258,73265..73267,73271..73273,73277..73282,
                     73349..73351,73355..73360,73367..73396,73400..73411,
                     73451..73453,73466..73471,73478..73483))
                     /gene="thiP"
                     /locus_tag="b0067"
                     /gene_synonym="ECK0068; JW0066; sfuB; yabK"
                     /note="dimer interface [polypeptide binding]; other site"
                     /db_xref="CDD:119394"
     misc_feature    complement(order(73082..73099,73349..73393))
                     /gene="thiP"
                     /locus_tag="b0067"
                     /gene_synonym="ECK0068; JW0066; sfuB; yabK"
                     /note="conserved gate region; other site"
                     /db_xref="CDD:119394"
     misc_feature    complement(order(73004..73006,73034..73036,73043..73045,
                     73079..73081,73295..73297,73349..73351))
                     /gene="thiP"
                     /locus_tag="b0067"
                     /gene_synonym="ECK0068; JW0066; sfuB; yabK"
                     /note="putative PBP binding loops; other site"
                     /db_xref="CDD:119394"
     misc_feature    complement(order(73151..73153,73163..73168,73184..73222))
                     /gene="thiP"
                     /locus_tag="b0067"
                     /gene_synonym="ECK0068; JW0066; sfuB; yabK"
                     /note="ABC-ATPase subunit interface; other site"
                     /db_xref="CDD:119394"
     gene            complement(74497..75480)
                     /gene="thiB"
                     /locus_tag="b0068"
                     /gene_synonym="ECK0069; JW0067; sfuA; tbpA; yabL"
                     /db_xref="EcoGene:EG11574"
                     /db_xref="GeneID:946306"
     CDS             complement(74497..75480)
                     /gene="thiB"
                     /locus_tag="b0068"
                     /gene_synonym="ECK0069; JW0067; sfuA; tbpA; yabL"
                     /function="transport; Transport of small molecules: Other"
                     /GO_component="GO:0042597 - periplasmic space"
                     /GO_process="GO:0009228 - thiamin biosynthetic process"
                     /note="thiamin-binding periplasmic protein;
                     periplasmic-binding component of ABC superfamily"
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine/thiamine pyrophosphate/thiamine
                     monophosphate ABC transporter periplasmic binding protein"
                     /protein_id="NP_414610.1"
                     /db_xref="GI:16128062"
                     /db_xref="ASAP:ABE-0000249"
                     /db_xref="UniProtKB/Swiss-Prot:P31550"
                     /db_xref="EcoGene:EG11574"
                     /db_xref="GeneID:946306"
                     /translation="MLKKCLPLLLLCTAPVFAKPVLTVYTYDSFAADWGPGPVVKKAF
                     EADCNCELKLVALEDGVSLLNRLRMEGKNSKADVVLGLDNNLLDAASKTGLFAKSGVA
                     ADAVNVPGGWNNDTFVPFDYGYFAFVYDKNKLKNPPQSLKELVESDQNWRVIYQDPRT
                     STPGLGLLLWMQKVYGDDAPQAWQKLAKKTVTVTKGWSEAYGLFLKGESDLVLSYTTS
                     PAYHILEEKKDNYAAANFSEGHYLQVEVAARTAASKQPELAQKFLQFMVSPAFQNAIP
                     TGNWMYPVANVTLPAGFEKLTKPATTLEFTPAEVAAQRQAWISEWQRAVSR"
     misc_feature    complement(74500..75444)
                     /gene="thiB"
                     /locus_tag="b0068"
                     /gene_synonym="ECK0069; JW0067; sfuA; tbpA; yabL"
                     /note="thiamine transporter substrate binding subunit;
                     Provisional; Region: tbpA; PRK11205"
                     /db_xref="CDD:236883"
     gene            complement(75644..77299)
                     /gene="sgrR"
                     /locus_tag="b0069"
                     /gene_synonym="ECK0070; JW0068; yabN"
                     /db_xref="EcoGene:EG12094"
                     /db_xref="GeneID:944788"
     CDS             complement(75644..77299)
                     /gene="sgrR"
                     /locus_tag="b0069"
                     /gene_synonym="ECK0070; JW0068; yabN"
                     /function="transport; Not classified"
                     /GO_component="GO:0042597 - periplasmic space"
                     /note="putative transport protein"
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional DNA-binding transcriptional
                     activator of sgrS sRNA"
                     /protein_id="NP_414611.1"
                     /db_xref="GI:16128063"
                     /db_xref="ASAP:ABE-0000251"
                     /db_xref="UniProtKB/Swiss-Prot:P33595"
                     /db_xref="EcoGene:EG12094"
                     /db_xref="GeneID:944788"
                     /translation="MPSARLQQQFIRLWQCCEGKSQDTTLNELAALLSCSRRHMRTLL
                     NTMQDRGWLTWEAEVGRGKRSRLTFLYTGLALQQQRAEDLLEQDRIDQLVQLVGDKAT
                     VRQMLVSHLGRSFRQGRHILRVLYYRPLRNLLPGSALRRSETHIARQIFSSLTRINEE
                     NGELEADIAHHWQQISPLHWRFFLRPGVHFHHGRELEMDDVIASLKRINTLPLYSHIA
                     DIVSPTPWTLDIHLTQPDRWLPLLLGQVPAMILPREWETLSNFASHPIGTGPYAVIRN
                     STNQLKIQAFDDFFGYRALIDEVNVWVLPEIADEPAGGLMLKGPQGEEKEIESRLEEG
                     CYYLLFDSRTHRGANQQVRDWVSYVLSPTNLVYFAEEQYQQLWFPAYGLLPRWHHART
                     IKSEKPAGLESLTLTFYQDHSEHRVIAGIMQQILASHQVTLKIKEIDYDQWHTGEIES
                     DIWLNSANFTLPLDFSVFAHLCEVPLLQHCIPIDWQADAARWRNGEMNLANWCQQLVA
                     SKAMVPLLHHWLIIQGQRSMRGLRMNTLGWFDFKSAWFAPPDP"
     misc_feature    complement(75647..77299)
                     /gene="sgrR"
                     /locus_tag="b0069"
                     /gene_synonym="ECK0070; JW0068; yabN"
                     /note="transcriptional regulator SgrR; Provisional;
                     Region: PRK13626"
                     /db_xref="CDD:184188"
     misc_feature    complement(76946..77287)
                     /gene="sgrR"
                     /locus_tag="b0069"
                     /gene_synonym="ECK0070; JW0068; yabN"
                     /note="Sugar transport-related sRNA regulator N-term;
                     Region: SgrR_N; pfam12793"
                     /db_xref="CDD:193269"
     misc_feature    complement(75659..76954)
                     /gene="sgrR"
                     /locus_tag="b0069"
                     /gene_synonym="ECK0070; JW0068; yabN"
                     /note="The C-terminal solute-binding domain of DNA-binding
                     transcriptional regulator SgrR is related to the ABC-type
                     oligopeptide-binding proteins and contains the type 2
                     periplasmic-binding fold; Region: PBP2_SgrR_like; cd08507"
                     /db_xref="CDD:173872"
     gene            77367..77593
                     /gene="sgrS"
                     /locus_tag="b4577"
                     /gene_synonym="ECK0071; JWR0259; ryaA"
                     /db_xref="EcoGene:EG31149"
                     /db_xref="GeneID:4056038"
     ncRNA           77367..77593
                     /gene="sgrS"
                     /locus_tag="b4577"
                     /gene_synonym="ECK0071; JWR0259; ryaA"
                     /ncRNA_class="antisense_RNA"
                     /product="sRNA antisense regulator destabilzes ptsG mRNA,
                     Hfq-dependent; regulated by sgrR"
                     /db_xref="ASAP:ABE-0285090"
                     /db_xref="EcoGene:EG31149"
                     /db_xref="GeneID:4056038"
     gene            77388..77519
                     /gene="sgrT"
                     /locus_tag="b4662"
                     /gene_synonym="ECK4477"
                     /db_xref="EcoGene:EG14467"
                     /db_xref="GeneID:7751624"
     CDS             77388..77519
                     /gene="sgrT"
                     /locus_tag="b4662"
                     /gene_synonym="ECK4477"
                     /codon_start=1
                     /transl_table=11
                     /product="inhibitor of glucose uptake"
                     /protein_id="YP_002791237.1"
                     /db_xref="GI:226524697"
                     /db_xref="UniProtKB/Swiss-Prot:C1P5Z7"
                     /db_xref="EcoGene:EG14467"
                     /db_xref="GeneID:7751624"
                     /translation="MRQFYQHYFTATAKLCWLRWLSVPQRLTMLEGLMQWDDRNSES"
     gene            77621..78799
                     /gene="setA"
                     /locus_tag="b0070"
                     /gene_synonym="ECK0072; JW0069; yabM"
                     /db_xref="EcoGene:EG11754"
                     /db_xref="GeneID:944793"
     CDS             77621..78799
                     /gene="setA"
                     /locus_tag="b0070"
                     /gene_synonym="ECK0072; JW0069; yabM"
                     /function="putative transport; Not classified"
                     /GO_component="GO:0009274 - peptidoglycan-based cell wall"
                     /GO_component="GO:0019866 - organelle inner membrane"
                     /GO_function="GO:0015543 - lactose/glucose efflux
                     transporter activity"
                     /GO_process="GO:0016052 - carbohydrate catabolic process"
                     /codon_start=1
                     /transl_table=11
                     /product="broad specificity sugar efflux system"
                     /protein_id="YP_025293.1"
                     /db_xref="GI:49175994"
                     /db_xref="ASAP:ABE-0000257"
                     /db_xref="UniProtKB/Swiss-Prot:P31675"
                     /db_xref="EcoGene:EG11754"
                     /db_xref="GeneID:944793"
                     /translation="MIWIMTMARRMNGVYAAFMLVAFMMGVAGALQAPTLSLFLSREV
                     GAQPFWIGLFYTVNAIAGIGVSLWLAKRSDSQGDRRKLIIFCCLMAIGNALLFAFNRH
                     YLTLITCGVLLASLANTAMPQLFALAREYADNSAREVVMFSSVMRAQLSLAWVIGPPL
                     AFMLALNYGFTVMFSIAAGIFTLSLVLIAFMLPSVARVELPSENALSMQGGWQDSNVR
                     MLFVASTLMWTCNTMYIIDMPLWISSELGLPDKLAGFLMGTAAGLEIPAMILAGYYVK
                     RYGKRRMMVIAVAAGVLFYTGLIFFNSRMALMTLQLFNAVFIGIVAGIGMLWFQDLMP
                     GRAGAATTLFTNSISTGVILAGVIQGAIAQSWGHFAVYWVIAVISVVALFLTAKVKDV
                     "
     misc_feature    77666..78790
                     /gene="setA"
                     /locus_tag="b0070"
                     /gene_synonym="ECK0072; JW0069; yabM"
                     /note="The Major Facilitator Superfamily (MFS) is a large
                     and diverse group of secondary transporters that includes
                     uniporters, symporters, and antiporters. MFS proteins
                     facilitate the transport across cytoplasmic or internal
                     membranes of a variety of...; Region: MFS; cd06174"
                     /db_xref="CDD:119392"
     misc_feature    77669..78793
                     /gene="setA"
                     /locus_tag="b0070"
                     /gene_synonym="ECK0072; JW0069; yabM"
                     /note="sugar efflux transporter; Region: 2A0120;
                     TIGR00899"
                     /db_xref="CDD:129977"
     misc_feature    order(77705..77707,77714..77722,77726..77731,77783..77785,
                     77792..77797,77804..77806,77816..77821,77825..77830,
                     77969..77974,77981..77986,77993..77998,78005..78007,
                     78041..78043,78050..78052,78059..78064,78080..78082,
                     78302..78304,78311..78316,78323..78328,78335..78337,
                     78377..78379,78389..78391,78401..78403,78410..78412,
                     78422..78424,78563..78565,78572..78577,78584..78586,
                     78596..78601,78608..78610,78638..78643,78650..78655,
                     78662..78667,78674..78676)
                     /gene="setA"
                     /locus_tag="b0070"
                     /gene_synonym="ECK0072; JW0069; yabM"
                     /note="putative substrate translocation pore; other site"
                     /db_xref="CDD:119392"
     gene            complement(78848..79453)
                     /gene="leuD"
                     /locus_tag="b0071"
                     /gene_synonym="ECK0073; JW0070"
                     /db_xref="EcoGene:EG11575"
                     /db_xref="GeneID:945642"
     CDS             complement(78848..79453)
                     /gene="leuD"
                     /locus_tag="b0071"
                     /gene_synonym="ECK0073; JW0070"
                     /EC_number="4.2.1.33"
                     /function="enzyme; Amino acid biosynthesis: Leucine"
                     /GO_component="GO:0005737 - cytoplasm"
                     /GO_process="GO:0009098 - leucine biosynthetic process"
                     /note="isopropylmalate isomerase subunit"
                     /codon_start=1
                     /transl_table=11
                     /product="3-isopropylmalate dehydratase small subunit"
                     /protein_id="NP_414613.1"
                     /db_xref="GI:16128065"
                     /db_xref="ASAP:ABE-0000259"
                     /db_xref="UniProtKB/Swiss-Prot:P30126"
                     /db_xref="EcoGene:EG11575"
                     /db_xref="GeneID:945642"
                     /translation="MAEKFIKHTGLVVPLDAANVDTDAIIPKQFLQKVTRTGFGAHLF
                     NDWRFLDEKGQQPNPDFVLNFPQYQGASILLARENFGCGSSREHAPWALTDYGFKVVI
                     APSFADIFYGNSFNNQLLPVKLSDAEVDELFALVKANPGIHFDVDLEAQEVKAGEKTY
                     RFTIDAFRRHCMMNGLDSIGLTLQHDDAIAAYEAKQPAFMN"
     misc_feature    complement(79010..79411)
                     /gene="leuD"
                     /locus_tag="b0071"
                     /gene_synonym="ECK0073; JW0070"
                     /note="Aconatase-like swivel domain of 3-isopropylmalate
                     dehydratase and related uncharacterized proteins.
                     3-isopropylmalate dehydratase catalyzes the isomerization
                     between 2-isopropylmalate and 3-isopropylmalate, via the
                     formation of 2-isopropylmaleate...; Region: IPMI_Swivel;
                     cd01577"
                     /db_xref="CDD:238809"
     misc_feature    complement(79196..79204)
                     /gene="leuD"
                     /locus_tag="b0071"
                     /gene_synonym="ECK0073; JW0070"
                     /note="substrate binding site [chemical binding]; other
                     site"
                     /db_xref="CDD:238809"
     gene            complement(79464..80864)
                     /gene="leuC"
                     /locus_tag="b0072"
                     /gene_synonym="ECK0074; JW0071"
                     /db_xref="EcoGene:EG11576"
                     /db_xref="GeneID:945076"
     CDS             complement(79464..80864)
                     /gene="leuC"
                     /locus_tag="b0072"
                     /gene_synonym="ECK0074; JW0071"
                     /EC_number="4.2.1.33"
                     /function="enzyme; Amino acid biosynthesis: Leucine"
                     /GO_component="GO:0005737 - cytoplasm"
                     /GO_process="GO:0009098 - leucine biosynthetic process"
                     /note="3-isopropylmalate isomerase (dehydratase) subunit"
                     /codon_start=1
                     /transl_table=11
                     /product="3-isopropylmalate dehydratase large subunit"
                     /protein_id="NP_414614.1"
                     /db_xref="GI:16128066"
                     /db_xref="ASAP:ABE-0000261"
                     /db_xref="UniProtKB/Swiss-Prot:P0A6A6"
                     /db_xref="EcoGene:EG11576"
                     /db_xref="GeneID:945076"
                     /translation="MAKTLYEKLFDAHVVYEAENETPLLYIDRHLVHEVTSPQAFDGL
                     RAHGRPVRQPGKTFATMDHNVSTQTKDINACGEMARIQMQELIKNCKEFGVELYDLNH
                     PYQGIVHVMGPEQGVTLPGMTIVCGDSHTATHGAFGALAFGIGTSEVEHVLATQTLKQ
                     GRAKTMKIEVQGKAAPGITAKDIVLAIIGKTGSAGGTGHVVEFCGEAIRDLSMEGRMT
                     LCNMAIEMGAKAGLVAPDETTFNYVKGRLHAPKGKDFDDAVAYWKTLQTDEGATFDTV
                     VTLQAEEISPQVTWGTNPGQVISVNDNIPDPASFADPVERASAEKALAYMGLKPGIPL
                     TEVAIDKVFIGSCTNSRIEDLRAAAEIAKGRKVAPGVQALVVPGSGPVKAQAEAEGLD
                     KIFIEAGFEWRLPGCSMCLAMNNDRLNPGERCASTSNRNFEGRQGRGGRTHLVSPAMA
                     AAAAVTGHFADIRNIK"
     misc_feature    complement(79488..80780)
                     /gene="leuC"
                     /locus_tag="b0072"
                     /gene_synonym="ECK0074; JW0071"
                     /note="3-isopropylmalate dehydratase catalyzes the
                     isomerization between 2-isopropylmalate and
                     3-isopropylmalate; Region: IPMI; cd01583"
                     /db_xref="CDD:153133"
     misc_feature    complement(order(79560..79562,79575..79577,79632..79634,
                     80478..80483,80757..80759,80766..80768))
                     /gene="leuC"
                     /locus_tag="b0072"
                     /gene_synonym="ECK0074; JW0071"
                     /note="substrate binding site [chemical binding]; other
                     site"
                     /db_xref="CDD:153133"
     misc_feature    complement(order(79578..79580,79632..79637,79644..79646,
                     79824..79826,80475..80477))
                     /gene="leuC"
                     /locus_tag="b0072"
                     /gene_synonym="ECK0074; JW0071"
                     /note="ligand binding site [chemical binding]; other site"
                     /db_xref="CDD:153133"
     gene            complement(80867..81958)
                     /gene="leuB"
                     /locus_tag="b0073"
                     /gene_synonym="ECK0075; JW5807"
                     /db_xref="EcoGene:EG11577"
                     /db_xref="GeneID:944798"
     CDS             complement(80867..81958)
                     /gene="leuB"
                     /locus_tag="b0073"
                     /gene_synonym="ECK0075; JW5807"
                     /EC_number="1.1.1.85"
                     /function="enzyme; Amino acid biosynthesis: Leucine"
                     /GO_component="GO:0005737 - cytoplasm"
                     /GO_process="GO:0009098 - leucine biosynthetic process"
                     /codon_start=1
                     /transl_table=11
                     /product="3-isopropylmalate dehydrogenase,
                     NAD(+)-dependent"
                     /protein_id="NP_414615.4"
                     /db_xref="GI:90111082"
                     /db_xref="ASAP:ABE-0000265"
                     /db_xref="UniProtKB/Swiss-Prot:P30125"
                     /db_xref="EcoGene:EG11577"
                     /db_xref="GeneID:944798"
                     /translation="MSKNYHIAVLPGDGIGPEVMTQALKVLDAVRNRFAMRITTSHYD
                     VGGAAIDNHGQPLPPATVEGCEQADAVLFGSVGGPKWEHLPPDQQPERGALLPLRKHF
                     KLFSNLRPAKLYQGLEAFCPLRADIAANGFDILCVRELTGGIYFGQPKGREGSGQYEK
                     AFDTEVYHRFEIERIARIAFESARKRRHKVTSIDKANVLQSSILWREIVNEIATEYPD
                     VELAHMYIDNATMQLIKDPSQFDVLLCSNLFGDILSDECAMITGSMGMLPSASLNEQG
                     FGLYEPAGGSAPDIAGKNIANPIAQILSLALLLRYSLDADDAACAIERAINRALEEGI
                     RTGDLARGAAAVSTDEMGDIIARYVAEGV"
     misc_feature    complement(80873..81952)
                     /gene="leuB"
                     /locus_tag="b0073"
                     /gene_synonym="ECK0075; JW5807"
                     /note="3-isopropylmalate dehydrogenase; Provisional;
                     Region: PRK00772"
                     /db_xref="CDD:234832"
     gene            complement(81958..83529)
                     /gene="leuA"
                     /locus_tag="b0074"
                     /gene_synonym="ECK0076; JW0073"
                     /db_xref="EcoGene:EG11226"
                     /db_xref="GeneID:947465"
     CDS             complement(81958..83529)
                     /gene="leuA"
                     /locus_tag="b0074"
                     /gene_synonym="ECK0076; JW0073"
                     /EC_number="2.3.3.13"
                     /function="enzyme; Amino acid biosynthesis: Leucine"
                     /GO_component="GO:0005737 - cytoplasm"
                     /GO_process="GO:0009098 - leucine biosynthetic process"
                     /codon_start=1
                     /transl_table=11
                     /product="2-isopropylmalate synthase"
                     /protein_id="NP_414616.1"
                     /db_xref="GI:16128068"
                     /db_xref="ASAP:ABE-0000267"
                     /db_xref="UniProtKB/Swiss-Prot:P09151"
                     /db_xref="EcoGene:EG11226"
                     /db_xref="GeneID:947465"
                     /translation="MSQQVIIFDTTLRDGEQALQASLSVKEKLQIALALERMGVDVME
                     VGFPVSSPGDFESVQTIARQVKNSRVCALARCVEKDIDVAAESLKVAEAFRIHTFIAT
                     SPMHIATKLRSTLDEVIERAIYMVKRARNYTDDVEFSCEDAGRTPIADLARVVEAAIN
                     AGATTINIPDTVGYTMPFEFAGIISGLYERVPNIDKAIISVHTHDDLGLAVGNSLAAV
                     HAGARQVEGAMNGIGERAGNCSLEEVIMAIKVRKDILNVHTAINHQEIWRTSQLVSQI
                     CNMPIPANKAIVGSGAFAHSSGIHQDGVLKNRENYEIMTPESIGLNQIQLNLTSRSGR
                     AAVKHRMDEMGYKESEYNLDNLYDAFLKLADKKGQVFDYDLEALAFIGKQQEEPEHFR
                     LDYFSVQSGSNDIATAAVKLACGEEVKAEAANGNGPVDAVYQAINRITEYNVELVKYS
                     LTAKGHGKDALGQVDIVANYNGRRFHGVGLATDIVESSAKAMVHVLNNIWRAAEVEKE
                     LQRKAQHNENNKETV"
     misc_feature    complement(81994..83529)
                     /gene="leuA"
                     /locus_tag="b0074"
                     /gene_synonym="ECK0076; JW0073"
                     /note="2-isopropylmalate synthase; Validated; Region:
                     PRK00915"
                     /db_xref="CDD:234864"
     misc_feature    complement(82705..83511)
                     /gene="leuA"
                     /locus_tag="b0074"
                     /gene_synonym="ECK0076; JW0073"
                     /note="2-isopropylmalate synthase (IPMS), N-terminal
                     catalytic TIM barrel domain; Region: DRE_TIM_IPMS;
                     cd07940"
                     /db_xref="CDD:163678"
     misc_feature    complement(order(82918..82920,82924..82926,83017..83019,
                     83023..83025,83107..83109,83113..83115,83239..83241,
                     83305..83307,83398..83400,83479..83481,83488..83493))
                     /gene="leuA"
                     /locus_tag="b0074"
                     /gene_synonym="ECK0076; JW0073"
                     /note="active site"
                     /db_xref="CDD:163678"
     misc_feature    complement(order(83398..83400,83488..83493))
                     /gene="leuA"
                     /locus_tag="b0074"
                     /gene_synonym="ECK0076; JW0073"
                     /note="catalytic residues [active]"
                     /db_xref="CDD:163678"
     misc_feature    complement(order(82918..82920,82924..82926))
                     /gene="leuA"
                     /locus_tag="b0074"
                     /gene_synonym="ECK0076; JW0073"
                     /note="metal binding site [ion binding]; metal-binding
                     site"
                     /db_xref="CDD:163678"
     misc_feature    complement(82033..82425)
                     /gene="leuA"
                     /locus_tag="b0074"
                     /gene_synonym="ECK0076; JW0073"
                     /note="LeuA allosteric (dimerisation) domain; Region:
                     LeuA_dimer; smart00917"
                     /db_xref="CDD:214910"
     gene            complement(83622..83708)
                     /gene="leuL"
                     /locus_tag="b0075"
                     /gene_synonym="ECK0077; JW0074; leuLP"
                     /db_xref="EcoGene:EG11280"
                     /db_xref="GeneID:946072"
     CDS             complement(83622..83708)
                     /gene="leuL"
                     /locus_tag="b0075"
                     /gene_synonym="ECK0077; JW0074; leuLP"
                     /function="leader; Amino acid biosynthesis: Leucine"
                     /GO_component="GO:0005737 - cytoplasm"
                     /GO_process="GO:0009098 - leucine biosynthetic process"
                     /codon_start=1
                     /transl_table=11
                     /product="leu operon leader peptide"
                     /protein_id="NP_414617.1"
                     /db_xref="GI:16128069"
                     /db_xref="ASAP:ABE-0000269"
                     /db_xref="UniProtKB/Swiss-Prot:P0AD79"
                     /db_xref="EcoGene:EG11280"
                     /db_xref="GeneID:946072"
                     /translation="MTHIVRFIGLLLLNASSLRGRRVSGIQH"
     misc_feature    complement(83625..83708)
                     /gene="leuL"
                     /locus_tag="b0075"
                     /gene_synonym="ECK0077; JW0074; leuLP"
                     /note="leu operon leader peptide; Provisional; Region:
                     PRK09925"
                     /db_xref="CDD:137592"
     gene            84368..85312
                     /gene="leuO"
                     /locus_tag="b0076"
                     /gene_synonym="ECK0078; JW0075"
                     /db_xref="EcoGene:EG10531"
                     /db_xref="GeneID:949034"
     CDS             84368..85312
                     /gene="leuO"
                     /locus_tag="b0076"
                     /gene_synonym="ECK0078; JW0075"
                     /function="putative regulator; Amino acid biosynthesis:
                     Leucine"
                     /GO_component="GO:0005737 - cytoplasm"
                     /GO_function="GO:0016563 - transcription activator
                     activity"
                     /GO_process="GO:0009098 - leucine biosynthetic process"
                     /GO_process="GO:0006350 - transcription"
                     /note="probable transcriptional activator for leuABCD
                     operon"
                     /codon_start=1
                     /transl_table=11
                     /product="global transcription factor"
                     /protein_id="NP_414618.4"
                     /db_xref="GI:90111083"
                     /db_xref="ASAP:ABE-0000280"
                     /db_xref="UniProtKB/Swiss-Prot:P10151"
                     /db_xref="EcoGene:EG10531"
                     /db_xref="GeneID:949034"
                     /translation="MPEVQTDHPETAELSKPQLRMVDLNLLTVFDAVMQEQNITRAAH
                     VLGMSQPAVSNAVARLKVMFNDELFVRYGRGIQPTARAFQLFGSVRQALQLVQNELPG
                     SGFEPASSERVFHLCVCSPLDSILTSQIYNHIEQIAPNIHVMFKSSLNQNTEHQLRYQ
                     ETEFVISYEDFHRPEFTSVPLFKDEMVLVASKNHPTIKGPLLKHDVYNEQHAAVSLDR
                     FASFSQPWYDTVDKQASIAYQGMAMMSVLSVVSQTHLVAIAPRWLAEEFAESLELQVL
                     PLPLKQNSRTCYLSWHEAAGRDKGHQWMEEQLVSICKR"
     misc_feature    84368..85309
                     /gene="leuO"
                     /locus_tag="b0076"
                     /gene_synonym="ECK0078; JW0075"
                     /note="leucine transcriptional activator; Reviewed;
                     Region: leuO; PRK09508"
                     /db_xref="CDD:181918"
     misc_feature    84437..84613
                     /gene="leuO"
                     /locus_tag="b0076"
                     /gene_synonym="ECK0078; JW0075"
                     /note="Bacterial regulatory helix-turn-helix protein, lysR
                     family; Region: HTH_1; pfam00126"
                     /db_xref="CDD:249610"
     misc_feature    84704..85300
                     /gene="leuO"
                     /locus_tag="b0076"
                     /gene_synonym="ECK0078; JW0075"
                     /note="The C-terminal substrate binding domain of
                     LysR-type transcriptional regulator LeuO, an activator of
                     leucine synthesis operon, contains the type 2 periplasmic
                     binding fold; Region: PBP2_LeuO; cd08466"
                     /db_xref="CDD:176155"
     misc_feature    order(84722..84724,84728..84733,84743..84745,84917..84919,
                     85025..85027,85226..85228)
                     /gene="leuO"
                     /locus_tag="b0076"
                     /gene_synonym="ECK0078; JW0075"
                     /note="putative substrate binding pocket [chemical
                     binding]; other site"
                     /db_xref="CDD:176155"
     misc_feature    order(84725..84727,84734..84739,84746..84751,84758..84763,
                     84767..84772,84779..84784,84788..84802,84806..84808,
                     84995..84997,85076..85090,85097..85102,85109..85114,
                     85121..85123,85163..85165)
                     /gene="leuO"
                     /locus_tag="b0076"
                     /gene_synonym="ECK0078; JW0075"
                     /note="putative dimerization interface [polypeptide
                     binding]; other site"
                     /db_xref="CDD:176155"
     gene            85630..87354
                     /gene="ilvI"
                     /locus_tag="b0077"
                     /gene_synonym="ECK0079; JW0076"
                     /db_xref="EcoGene:EG10500"
                     /db_xref="GeneID:948793"
     CDS             85630..87354
                     /gene="ilvI"
                     /locus_tag="b0077"
                     /gene_synonym="ECK0079; JW0076"
                     /EC_number="2.2.1.6"
                     /function="enzyme; Amino acid biosynthesis: Isoleucine,
                     Valine"
                     /experiment="N-terminus verified by Edman degradation:
                     PMID 3881131,9298646"
                     /note="acetolactate synthase III, valine sensitive, large
                     subunit"
                     /codon_start=1
                     /transl_table=11
                     /product="acetolactate synthase 3 large subunit"
                     /protein_id="YP_025294.2"
                     /db_xref="GI:90111084"
                     /db_xref="ASAP:ABE-0000290"
                     /db_xref="UniProtKB/Swiss-Prot:P00893"
                     /db_xref="EcoGene:EG10500"
                     /db_xref="GeneID:948793"
                     /translation="MEMLSGAEMVVRSLIDQGVKQVFGYPGGAVLDIYDALHTVGGID
                     HVLVRHEQAAVHMADGLARATGEVGVVLVTSGPGATNAITGIATAYMDSIPLVVLSGQ
                     VATSLIGYDAFQECDMVGISRPVVKHSFLVKQTEDIPQVLKKAFWLAASGRPGPVVVD
                     LPKDILNPANKLPYVWPESVSMRSYNPTTTGHKGQIKRALQTLVAAKKPVVYVGGGAI
                     TAGCHQQLKETVEALNLPVVCSLMGLGAFPATHRQALGMLGMHGTYEANMTMHNADVI
                     FAVGVRFDDRTTNNLAKYCPNATVLHIDIDPTSISKTVTADIPIVGDARQVLEQMLEL
                     LSQESAHQPLDEIRDWWQQIEQWRARQCLKYDTHSEKIKPQAVIETLWRLTKGDAYVT
                     SDVGQHQMFAALYYPFDKPRRWINSGGLGTMGFGLPAALGVKMALPEETVVCVTGDGS
                     IQMNIQELSTALQYELPVLVVNLNNRYLGMVKQWQDMIYSGRHSQSYMQSLPDFVRLA
                     EAYGHVGIQISHPHELESKLSEALEQVRNNRLVFVDVTVDGSEHVYPMQIRGGGMDEM
                     WLSKTERT"
     misc_feature    85630..87351
                     /gene="ilvI"
                     /locus_tag="b0077"
                     /gene_synonym="ECK0079; JW0076"
                     /note="acetolactate synthase 3 catalytic subunit;
                     Validated; Region: PRK07979"
                     /db_xref="CDD:181185"
     misc_feature    85651..86118
                     /gene="ilvI"
                     /locus_tag="b0077"
                     /gene_synonym="ECK0079; JW0076"
                     /note="Pyrimidine (PYR) binding domain of POX and related
                     proteins; Region: TPP_PYR_POX_like; cd07035"
                     /db_xref="CDD:132918"
     misc_feature    order(85690..85692,85705..85710,85720..85722,85732..85734,
                     85759..85779,85786..85788,85795..85800,85807..85812,
                     85816..85824,85858..85860,85879..85881,85891..85893,
                     85900..85905)
                     /gene="ilvI"
                     /locus_tag="b0077"
                     /gene_synonym="ECK0079; JW0076"
                     /note="PYR/PP interface [polypeptide binding]; other site"
                     /db_xref="CDD:132918"
     misc_feature    order(85705..85713,85720..85722,85732..85734,85762..85764,
                     85768..85779,85783..85785,85858..85860,85867..85872,
                     85876..85881,85888..85890,85990..85992,85999..86001)
                     /gene="ilvI"
                     /locus_tag="b0077"
                     /gene_synonym="ECK0079; JW0076"
                     /note="dimer interface [polypeptide binding]; other site"
                     /db_xref="CDD:132918"
     misc_feature    order(85705..85707,85780..85782,85858..85860,85870..85872)
                     /gene="ilvI"
                     /locus_tag="b0077"
                     /gene_synonym="ECK0079; JW0076"
                     /note="TPP binding site [chemical binding]; other site"
                     /db_xref="CDD:132918"
     misc_feature    86215..86622
                     /gene="ilvI"
                     /locus_tag="b0077"
                     /gene_synonym="ECK0079; JW0076"
                     /note="Thiamine pyrophosphate enzyme, central domain;
                     Region: TPP_enzyme_M; pfam00205"
                     /db_xref="CDD:249676"
     misc_feature    86743..87297
                     /gene="ilvI"
                     /locus_tag="b0077"
                     /gene_synonym="ECK0079; JW0076"
                     /note="Thiamine pyrophosphate (TPP) family,
                     Acetohydroxyacid synthase (AHAS) subfamily, TPP-binding
                     module; composed of proteins similar to the large
                     catalytic subunit of AHAS. AHAS catalyzes the condensation
                     of two molecules of pyruvate to give the...; Region:
                     TPP_AHAS; cd02015"
                     /db_xref="CDD:238973"
     misc_feature    order(86812..86823,86890..86892,86896..86898,86971..86979,
                     86986..86988,87052..87054)
                     /gene="ilvI"
                     /locus_tag="b0077"
                     /gene_synonym="ECK0079; JW0076"
                     /note="TPP-binding site [chemical binding]; other site"
                     /db_xref="CDD:238973"
     misc_feature    order(86881..86883,86890..86892,86896..86898,86983..86988,
                     86992..86997,87016..87018,87133..87138,87148..87150,
                     87157..87159)
                     /gene="ilvI"
                     /locus_tag="b0077"
                     /gene_synonym="ECK0079; JW0076"
                     /note="dimer interface [polypeptide binding]; other site"
                     /db_xref="CDD:238973"
     gene            87357..87848
                     /gene="ilvH"
                     /locus_tag="b0078"
                     /gene_synonym="brnP; ECK0080; JW0077"
                     /db_xref="EcoGene:EG10499"
                     /db_xref="GeneID:947267"
     CDS             87357..87848
                     /gene="ilvH"
                     /locus_tag="b0078"
                     /gene_synonym="brnP; ECK0080; JW0077"
                     /EC_number="2.2.1.6"
                     /function="enzyme; Amino acid biosynthesis: Isoleucine,
                     Valine"
                     /note="acetolactate synthase III, valine sensitive, small
                     subunit"
                     /codon_start=1
                     /transl_table=11
                     /product="acetolactate synthase 3, small subunit,
                     valine-sensitive"
                     /protein_id="NP_414620.1"
                     /db_xref="GI:16128071"
                     /db_xref="ASAP:ABE-0000294"
                     /db_xref="UniProtKB/Swiss-Prot:P00894"
                     /db_xref="EcoGene:EG10499"
                     /db_xref="GeneID:947267"
                     /translation="MRRILSVLLENESGALSRVIGLFSQRGYNIESLTVAPTDDPTLS
                     RMTIQTVGDEKVLEQIEKQLHKLVDVLRVSELGQGAHVEREIMLVKIQASGYGRDEVK
                     RNTEIFRGQIIDVTPSLYTVQLAGTSGKLDAFLASIRDVAKIVEVARSGVVGLSRGDK
                     IMR"
     misc_feature    87357..87842
                     /gene="ilvH"
                     /locus_tag="b0078"
                     /gene_synonym="brnP; ECK0080; JW0077"
                     /note="acetolactate synthase 3 regulatory subunit;
                     Reviewed; Region: ilvH; PRK11895"
                     /db_xref="CDD:183365"
     misc_feature    87363..87578
                     /gene="ilvH"
                     /locus_tag="b0078"
                     /gene_synonym="brnP; ECK0080; JW0077"
                     /note="N-terminal ACT domain of the Escherichia coli
                     IlvH-like regulatory subunit of acetohydroxyacid synthase
                     (AHAS); Region: ACT_AHAS; cd04878"
                     /db_xref="CDD:153150"
     misc_feature    order(87381..87383,87387..87389,87402..87404,87441..87446,
                     87459..87461,87486..87488)
                     /gene="ilvH"
                     /locus_tag="b0078"
                     /gene_synonym="brnP; ECK0080; JW0077"
                     /note="putative valine binding site [chemical binding];
                     other site"
                     /db_xref="CDD:153150"
     misc_feature    order(87393..87398,87405..87407,87426..87428,87435..87437,
                     87447..87461,87489..87491)
                     /gene="ilvH"
                     /locus_tag="b0078"
                     /gene_synonym="brnP; ECK0080; JW0077"
                     /note="dimer interface [polypeptide binding]; other site"
                     /db_xref="CDD:153150"
     misc_feature    87603..87830
                     /gene="ilvH"
                     /locus_tag="b0078"
                     /gene_synonym="brnP; ECK0080; JW0077"
                     /note="Small subunit of acetolactate synthase; Region:
                     ALS_ss_C; pfam10369"
                     /db_xref="CDD:255942"
     gene            88028..89032
                     /gene="cra"
                     /locus_tag="b0080"
                     /gene_synonym="ECK0081; fruC; fruR; fruS?; JW0078; serR?;
                     shl"
                     /db_xref="EcoGene:EG10338"
                     /db_xref="GeneID:944804"
     CDS             88028..89032
                     /gene="cra"
                     /locus_tag="b0080"
                     /gene_synonym="ECK0081; fruC; fruR; fruS?; JW0078; serR?;
                     shl"
                     /function="regulator; Energy metabolism, carbon:
                     Glycolysis"
                     /GO_component="GO:0005737 - cytoplasm"
                     /GO_function="GO:0016563 - transcription activator
                     activity"
                     /GO_function="GO:0016564 - transcription repressor
                     activity"
                     /GO_process="GO:0006096 - glycolysis"
                     /GO_process="GO:0006350 - transcription"
                     /note="transcriptional repressor of fru operon and others"
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor-activator for carbon
                     metabolism"
                     /protein_id="NP_414622.1"
                     /db_xref="GI:16128073"
                     /db_xref="ASAP:ABE-0000299"
                     /db_xref="UniProtKB/Swiss-Prot:P0ACP1"
                     /db_xref="EcoGene:EG10338"
                     /db_xref="GeneID:944804"
                     /translation="MKLDEIARLAGVSRTTASYVINGKAKQYRVSDKTVEKVMAVVRE
                     HNYHPNAVAAGLRAGRTRSIGLVIPDLENTSYTRIANYLERQARQRGYQLLIACSEDQ
                     PDNEMRCIEHLLQRQVDAIIVSTSLPPEHPFYQRWANDPFPIVALDRALDREHFTSVV
                     GADQDDAEMLAEELRKFPAETVLYLGALPELSVSFLREQGFRTAWKDDPREVHFLYAN
                     SYEREAAAQLFEKWLETHPMPQALFTTSFALLQGVMDVTLRRDGKLPSDLAIATFGDN
                     ELLDFLQCPVLAVAQRHRDVAERVLEIVLASLDEPRKPKPGLTRIKRNLYRRGVLSRS
                     "
     misc_feature    88028..89011
                     /gene="cra"
                     /locus_tag="b0080"
                     /gene_synonym="ECK0081; fruC; fruR; fruS?; JW0078; serR?;
                     shl"
                     /note="DNA-binding transcriptional regulator FruR;
                     Provisional; Region: PRK11303"
                     /db_xref="CDD:236897"
     misc_feature    88040..88201
                     /gene="cra"
                     /locus_tag="b0080"
                     /gene_synonym="ECK0081; fruC; fruR; fruS?; JW0078; serR?;
                     shl"
                     /note="Helix-turn-helix (HTH) DNA binding domain of the
                     LacI family of transcriptional regulators; Region:
                     HTH_LacI; cd01392"
                     /db_xref="CDD:143331"
     misc_feature    order(88061..88075,88079..88084,88091..88093,88115..88120,
                     88127..88129,88166..88168,88175..88177,88184..88189,
                     88193..88198)
                     /gene="cra"
                     /locus_tag="b0080"
                     /gene_synonym="ECK0081; fruC; fruR; fruS?; JW0078; serR?;
                     shl"
                     /note="DNA binding site [nucleotide binding]"
                     /db_xref="CDD:143331"
     misc_feature    88166..88195
                     /gene="cra"
                     /locus_tag="b0080"
                     /gene_synonym="ECK0081; fruC; fruR; fruS?; JW0078; serR?;
                     shl"
                     /note="domain linker motif; other site"
                     /db_xref="CDD:143331"
     misc_feature    88214..89005
                     /gene="cra"
                     /locus_tag="b0080"
                     /gene_synonym="ECK0081; fruC; fruR; fruS?; JW0078; serR?;
                     shl"
                     /note="Ligand binding domain of DNA transcription
                     repressor specific for fructose (FruR) and its close
                     homologs; Region: PBP1_FruR; cd06274"
                     /db_xref="CDD:107269"
     misc_feature    order(88238..88240,88268..88273,88277..88282,88289..88291,
                     88304..88306,88313..88315,88319..88321,88373..88375,
                     88778..88780,88868..88870,88874..88876)
                     /gene="cra"
                     /locus_tag="b0080"
                     /gene_synonym="ECK0081; fruC; fruR; fruS?; JW0078; serR?;
                     shl"
                     /note="dimerization interface [polypeptide binding]; other
                     site"
                     /db_xref="CDD:107269"
     misc_feature    order(88250..88252,88262..88264,88463..88468,88499..88510,
                     88616..88618,88763..88765,88847..88849)
                     /gene="cra"
                     /locus_tag="b0080"
                     /gene_synonym="ECK0081; fruC; fruR; fruS?; JW0078; serR?;
                     shl"
                     /note="ligand binding site [chemical binding]; other site"
                     /db_xref="CDD:107269"
     gene            89634..90092
                     /gene="mraZ"
                     /locus_tag="b0081"
                     /gene_synonym="ECK0082; JW0079; yabB"
                     /db_xref="EcoGene:EG11084"
                     /db_xref="GeneID:944810"
     CDS             89634..90092
                     /gene="mraZ"
                     /locus_tag="b0081"
                     /gene_synonym="ECK0082; JW0079; yabB"
                     /codon_start=1
                     /transl_table=11
                     /product="RsmH methytransferase inhibitor"
                     /protein_id="NP_414623.1"
                     /db_xref="GI:16128074"
                     /db_xref="ASAP:ABE-0000302"
                     /db_xref="UniProtKB/Swiss-Prot:P22186"
                     /db_xref="EcoGene:EG11084"
                     /db_xref="GeneID:944810"
                     /translation="MFRGATLVNLDSKGRLSVPTRYREQLLENAAGQMVCTIDIYHPC
                     LLLYPLPEWEIIEQKLSRLSSMNPVERRVQRLLLGHASECQMDGAGRLLIAPVLRQHA
                     GLTKEVMLVGQFNKFELWDETTWHQQVKEDIDAEQLATGDLSERLQDLSL"
     misc_feature    89634..90086
                     /gene="mraZ"
                     /locus_tag="b0081"
                     /gene_synonym="ECK0082; JW0079; yabB"
                     /note="mraZ protein; Region: TIGR00242"
                     /db_xref="CDD:129345"
     misc_feature    89634..89861
                     /gene="mraZ"
                     /locus_tag="b0081"
                     /gene_synonym="ECK0082; JW0079; yabB"
                     /note="MraZ protein; Region: MraZ; pfam02381"
                     /db_xref="CDD:111290"
     misc_feature    89862..90038
                     /gene="mraZ"
                     /locus_tag="b0081"
                     /gene_synonym="ECK0082; JW0079; yabB"
                     /note="MraZ protein; Region: MraZ; pfam02381"
                     /db_xref="CDD:111290"
     gene            90094..91035
                     /gene="rsmH"
                     /locus_tag="b0082"
                     /gene_synonym="ECK0083; JW0080; mraW; yabC"
                     /db_xref="EcoGene:EG11085"
                     /db_xref="GeneID:944806"
     CDS             90094..91035
                     /gene="rsmH"
                     /locus_tag="b0082"
                     /gene_synonym="ECK0083; JW0080; mraW; yabC"
                     /EC_number="2.1.1.-"
                     /function="enzyme; rRNA modification"
                     /experiment="N-terminus verified by Edman degradation:
                     PMID 10572301"
                     /GO_process="GO:0042158 - lipoprotein biosynthetic
                     process"
                     /note="putative apolipoprotein"
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA m(4)C1402 methyltransferase,
                     SAM-dependent"
                     /protein_id="NP_414624.1"
                     /db_xref="GI:16128075"
                     /db_xref="ASAP:ABE-0000304"
                     /db_xref="UniProtKB/Swiss-Prot:P60390"
                     /db_xref="EcoGene:EG11085"
                     /db_xref="GeneID:944806"
                     /translation="MMENYKHTTVLLDEAVNGLNIRPDGIYIDGTFGRGGHSRLILSQ
                     LGEEGRLLAIDRDPQAIAVAKTIDDPRFSIIHGPFSALGEYVAERDLIGKIDGILLDL
                     GVSSPQLDDAERGFSFMRDGPLDMRMDPTRGQSAAEWLQTAEEADIAWVLKTYGEERF
                     AKRIARAIVERNREQPMTRTKELAEVVAAATPVKDKFKHPATRTFQAVRIWVNSELEE
                     IEQALKSSLNVLAPGGRLSIISFHSLEDRIVKRFMRENSRGPQVPAGLPMTEEQLKKL
                     GGRQLRALGKLMPGEEEVAENPRARSSVLRIAERTNA"
     misc_feature    90106..91029
                     /gene="rsmH"
                     /locus_tag="b0082"
                     /gene_synonym="ECK0083; JW0080; mraW; yabC"
                     /note="16S rRNA m(4)C1402 methyltranserfase; Provisional;
                     Region: PRK00050"
                     /db_xref="CDD:234597"
     gene            91032..91397
                     /gene="ftsL"
                     /locus_tag="b0083"
                     /gene_synonym="ECK0084; JW0081; mraR; yabD"
                     /db_xref="EcoGene:EG11086"
                     /db_xref="GeneID:944803"
     CDS             91032..91397
                     /gene="ftsL"
                     /locus_tag="b0083"
                     /gene_synonym="ECK0084; JW0081; mraR; yabD"
                     /function="phenotype; Cell division"
                     /note="cell division protein; ingrowth of wall at septum"
                     /codon_start=1
                     /transl_table=11
                     /product="membrane bound cell division leucine zipper
                     septum protein"
                     /protein_id="NP_414625.1"
                     /db_xref="GI:16128076"
                     /db_xref="ASAP:ABE-0000306"
                     /db_xref="UniProtKB/Swiss-Prot:P0AEN4"
                     /db_xref="EcoGene:EG11086"
                     /db_xref="GeneID:944803"
                     /translation="MISRVTEALSKVKGSMGSHERHALPGVIGDDLLRFGKLPLCLFI
                     CIILTAVTVVTTAHHTRLLTAQREQLVLERDALDIEWRNLILEENALGDHSRVERIAT
                     EKLQMQHVDPSQENIVVQK"
     misc_feature    91080..91394
                     /gene="ftsL"
                     /locus_tag="b0083"
                     /gene_synonym="ECK0084; JW0081; mraR; yabD"
                     /note="cell division protein FtsL; Provisional; Region:
                     PRK10772"
                     /db_xref="CDD:182717"
     gene            91413..93179
                     /gene="ftsI"
                     /locus_tag="b0084"
                     /gene_synonym="ECK0085; JW0082; pbpB; sep"
                     /db_xref="EcoGene:EG10341"
                     /db_xref="GeneID:944799"
     CDS             91413..93179
                     /gene="ftsI"
                     /locus_tag="b0084"
                     /gene_synonym="ECK0085; JW0082; pbpB; sep"
                     /function="enzyme; Cell division"
                     /GO_component="GO:0009274 - peptidoglycan-based cell wall"
                     /GO_component="GO:0019866 - organelle inner membrane"
                     /GO_process="GO:0009252 - peptidoglycan biosynthetic
                     process"
                     /GO_process="GO:0042493 - response to drug"
                     /note="septum formation; penicillin-binding protein 3;
                     peptidoglycan synthetase"
                     /codon_start=1
                     /transl_table=11
                     /product="transpeptidase involved in septal peptidoglycan
                     synthesis; penicillin-binding protein 3"
                     /protein_id="NP_414626.1"
                     /db_xref="GI:16128077"
                     /db_xref="ASAP:ABE-0000309"
                     /db_xref="UniProtKB/Swiss-Prot:P0AD68"
                     /db_xref="EcoGene:EG10341"
                     /db_xref="GeneID:944799"
                     /translation="MKAAAKTQKPKRQEEHANFISWRFALLCGCILLALAFLLGRVAW
                     LQVISPDMLVKEGDMRSLRVQQVSTSRGMITDRSGRPLAVSVPVKAIWADPKEVHDAG
                     GISVGDRWKALANALNIPLDQLSARINANPKGRFIYLARQVNPDMADYIKKLKLPGIH
                     LREESRRYYPSGEVTAHLIGFTNVDSQGIEGVEKSFDKWLTGQPGERIVRKDRYGRVI
                     EDISSTDSQAAHNLALSIDERLQALVYRELNNAVAFNKAESGSAVLVDVNTGEVLAMA
                     NSPSYNPNNLSGTPKEAMRNRTITDVFEPGSTVKPMVVMTALQRGVVRENSVLNTIPY
                     RINGHEIKDVARYSELTLTGVLQKSSNVGVSKLALAMPSSALVDTYSRFGLGKATNLG
                     LVGERSGLYPQKQRWSDIERATFSFGYGLMVTPLQLARVYATIGSYGIYRPLSITKVD
                     PPVPGERVFPESIVRTVVHMMESVALPGGGGVKAAIKGYRIAIKTGTAKKVGPDGRYI
                     NKYIAYTAGVAPASQPRFALVVVINDPQAGKYYGGAVSAPVFGAIMGGVLRTMNIEPD
                     ALTTGDKNEFVINQGEGTGGRS"
     misc_feature    91416..93149
                     /gene="ftsI"
                     /locus_tag="b0084"
                     /gene_synonym="ECK0085; JW0082; pbpB; sep"
                     /note="peptidoglycan synthase FtsI; Provisional; Region:
                     PRK15105"
                     /db_xref="CDD:185060"
     misc_feature    91623..92078
                     /gene="ftsI"
                     /locus_tag="b0084"
                     /gene_synonym="ECK0085; JW0082; pbpB; sep"
                     /note="Penicillin-binding Protein dimerization domain;
                     Region: PBP_dimer; pfam03717"
                     /db_xref="CDD:252119"
     misc_feature    92190..93074
                     /gene="ftsI"
                     /locus_tag="b0084"
                     /gene_synonym="ECK0085; JW0082; pbpB; sep"
                     /note="Penicillin binding protein transpeptidase domain;
                     Region: Transpeptidase; pfam00905"
                     /db_xref="CDD:250215"
     gene            93166..94653
                     /gene="murE"
                     /locus_tag="b0085"
                     /gene_synonym="ECK0086; JW0083"
                     /db_xref="EcoGene:EG10621"
                     /db_xref="GeneID:944791"
     CDS             93166..94653
                     /gene="murE"
                     /locus_tag="b0085"
                     /gene_synonym="ECK0086; JW0083"
                     /EC_number="6.3.2.13"
                     /function="enzyme; Murein sacculus, peptidoglycan"
                     /GO_component="GO:0009274 - peptidoglycan-based cell wall"
                     /GO_process="GO:0009252 - peptidoglycan biosynthetic
                     process"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-L-alanyl-D-glutamate:meso-
                     diaminopimelate ligase"
                     /protein_id="NP_414627.1"
                     /db_xref="GI:16128078"
                     /db_xref="ASAP:ABE-0000311"
                     /db_xref="UniProtKB/Swiss-Prot:P22188"
                     /db_xref="EcoGene:EG10621"
                     /db_xref="GeneID:944791"
                     /translation="MADRNLRDLLAPWVPDAPSRALREMTLDSRVAAAGDLFVAVVGH
                     QADGRRYIPQAIAQGVAAIIAEAKDEATDGEIREMHGVPVIYLSQLNERLSALAGRFY
                     HEPSDNLRLVGVTGTNGKTTTTQLLAQWSQLLGEISAVMGTVGNGLLGKVIPTENTTG
                     SAVDVQHELAGLVDQGATFCAMEVSSHGLVQHRVAALKFAASVFTNLSRDHLDYHGDM
                     EHYEAAKWLLYSEHHCGQAIINADDEVGRRWLAKLPDAVAVSMEDHINPNCHGRWLKA
                     TEVNYHDSGATIRFSSSWGDGEIESHLMGAFNVSNLLLALATLLALGYPLADLLKTAA
                     RLQPVCGRMEVFTAPGKPTVVVDYAHTPDALEKALQAARLHCAGKLWCVFGCGGDRDK
                     GKRPLMGAIAEEFADVAVVTDDNPRTEEPRAIINDILAGMLDAGHAKVMEGRAEAVTC
                     AVMQAKENDVVLVAGKGHEDYQIVGNQRLDYSDRVTVARLLGVIA"
     misc_feature    93166..94647
                     /gene="murE"
                     /locus_tag="b0085"
                     /gene_synonym="ECK0086; JW0083"
                     /note="UDP-N-acetylmuramoylalanyl-D-glutamate--2,
                     6-diaminopimelate ligase; Provisional; Region: murE;
                     PRK00139"
                     /db_xref="CDD:234660"
     misc_feature    93238..93471
                     /gene="murE"
                     /locus_tag="b0085"
                     /gene_synonym="ECK0086; JW0083"
                     /note="Mur ligase family, catalytic domain; Region:
                     Mur_ligase; pfam01225"
                     /db_xref="CDD:250458"
     misc_feature    93538..94098
                     /gene="murE"
                     /locus_tag="b0085"
                     /gene_synonym="ECK0086; JW0083"
                     /note="Mur ligase middle domain; Region: Mur_ligase_M;
                     pfam08245"
                     /db_xref="CDD:254689"
     misc_feature    94180..94440
                     /gene="murE"
                     /locus_tag="b0085"
                     /gene_synonym="ECK0086; JW0083"
                     /note="Mur ligase family, glutamate ligase domain; Region:
                     Mur_ligase_C; pfam02875"
                     /db_xref="CDD:251584"
     gene            94650..96008
                     /gene="murF"
                     /locus_tag="b0086"
                     /gene_synonym="ECK0087; JW0084; mra"
                     /db_xref="EcoGene:EG10622"
                     /db_xref="GeneID:944813"
     CDS             94650..96008
                     /gene="murF"
                     /locus_tag="b0086"
                     /gene_synonym="ECK0087; JW0084; mra"
                     /EC_number="6.3.2.10"
                     /function="enzyme; Murein sacculus, peptidoglycan"
                     /experiment="N-terminus verified by Edman degradation:
                     PMID 2186811"
                     /GO_component="GO:0009274 - peptidoglycan-based cell wall"
                     /GO_component="GO:0005737 - cytoplasm"
                     /GO_process="GO:0009252 - peptidoglycan biosynthetic
                     process"
                     /GO_process="GO:0000270 - peptidoglycan metabolic process"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-tripeptide:D-alanyl-D-
                     alanine ligase"
                     /protein_id="NP_414628.1"
                     /db_xref="GI:16128079"
                     /db_xref="ASAP:ABE-0000313"
                     /db_xref="UniProtKB/Swiss-Prot:P11880"
                     /db_xref="EcoGene:EG10622"
                     /db_xref="GeneID:944813"
                     /translation="MISVTLSQLTDILNGELQGADITLDAVTTDTRKLTPGCLFVALK
                     GERFDAHDFADQAKAGGAGALLVSRPLDIDLPQLIVKDTRLAFGELAAWVRQQVPARV
                     VALTGSSGKTSVKEMTAAILSQCGNTLYTAGNLNNDIGVPMTLLRLTPEYDYAVIELG
                     ANHQGEIAWTVSLTRPEAALVNNLAAAHLEGFGSLAGVAKAKGEIFSGLPENGIAIMN
                     ADNNDWLNWQSVIGSRKVWRFSPNAANSDFTATNIHVTSHGTEFTLQTPTGSVDVLLP
                     LPGRHNIANALAAAALSMSVGATLDAIKAGLANLKAVPGRLFPIQLAENQLLLDDSYN
                     ANVGSMTAAVQVLAEMPGYRVLVVGDMAELGAESEACHVQVGEAAKAAGIDRVLSVGK
                     QSHAISTASGVGEHFADKTALITRLKLLIAEQQVITILVKGSRSAAMEEVVRALQENG
                     TC"
     misc_feature    94650..96005
                     /gene="murF"
                     /locus_tag="b0086"
                     /gene_synonym="ECK0087; JW0084; mra"
                     /note="UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine
                     ligase; Reviewed; Region: murF; PRK10773"
                     /db_xref="CDD:182718"
     misc_feature    94728..94934
                     /gene="murF"
                     /locus_tag="b0086"
                     /gene_synonym="ECK0087; JW0084; mra"
                     /note="Mur ligase family, catalytic domain; Region:
                     Mur_ligase; pfam01225"
                     /db_xref="CDD:250458"
     misc_feature    94965..95498
                     /gene="murF"
                     /locus_tag="b0086"
                     /gene_synonym="ECK0087; JW0084; mra"
                     /note="Mur ligase middle domain; Region: Mur_ligase_M;
                     pfam08245"
                     /db_xref="CDD:254689"
     misc_feature    95586..95858
                     /gene="murF"
                     /locus_tag="b0086"
                     /gene_synonym="ECK0087; JW0084; mra"
                     /note="Mur ligase family, glutamate ligase domain; Region:
                     Mur_ligase_C; pfam02875"
                     /db_xref="CDD:251584"
     gene            96002..97084
                     /gene="mraY"
                     /locus_tag="b0087"
                     /gene_synonym="ECK0088; JW0085; murX"
                     /db_xref="EcoGene:EG10604"
                     /db_xref="GeneID:944814"
     CDS             96002..97084
                     /gene="mraY"
                     /locus_tag="b0087"
                     /gene_synonym="ECK0088; JW0085; murX"
                     /EC_number="2.7.8.13"
                     /function="enzyme; Murein sacculus, peptidoglycan"
                     /GO_component="GO:0009274 - peptidoglycan-based cell wall"
                     /GO_component="GO:0019866 - organelle inner membrane"
                     /GO_process="GO:0009252 - peptidoglycan biosynthetic
                     process"
                     /note="phospho-N-acetylmuramoyl-pentapeptide transferase?"
                     /codon_start=1
                     /transl_table=11
                     /product="phospho-N-acetylmuramoyl-pentapeptide
                     transferase"
                     /protein_id="NP_414629.1"
                     /db_xref="GI:16128080"
                     /db_xref="ASAP:ABE-0000316"
                     /db_xref="UniProtKB/Swiss-Prot:P0A6W3"
                     /db_xref="EcoGene:EG10604"
                     /db_xref="GeneID:944814"
                     /translation="MLVWLAEHLVKYYSGFNVFSYLTFRAIVSLLTALFISLWMGPRM
                     IAHLQKLSFGQVVRNDGPESHFSKRGTPTMGGIMILTAIVISVLLWAYPSNPYVWCVL
                     VVLVGYGVIGFVDDYRKVVRKDTKGLIARWKYFWMSVIALGVAFALYLAGKDTPATQL
                     VVPFFKDVMPQLGLFYILLAYFVIVGTGNAVNLTDGLDGLAIMPTVFVAGGFALVAWA
                     TGNMNFASYLHIPYLRHAGELVIVCTAIVGAGLGFLWFNTYPAQVFMGDVGSLALGGA
                     LGIIAVLLRQEFLLVIMGGVFVVETLSVILQVGSFKLRGQRIFRMAPIHHHYELKGWP
                     EPRVIVRFWIISLMLVLIGLATLKVR"
     misc_feature    96182..97069
                     /gene="mraY"
                     /locus_tag="b0087"
                     /gene_synonym="ECK0088; JW0085; murX"
                     /note="Phospho-N-acetylmuramoyl-pentapeptide-transferase
                     (mraY) is an enzyme responsible for the formation of the
                     first lipid intermediate in the synthesis of bacterial
                     cell wall peptidoglycan. It catalyzes the formation of...;
                     Region: GT_MraY; cd06852"
                     /db_xref="CDD:133462"
     misc_feature    96344..96349
                     /gene="mraY"
                     /locus_tag="b0087"
                     /gene_synonym="ECK0088; JW0085; murX"
                     /note="Mg++ binding site [ion binding]; other site"
                     /db_xref="CDD:133462"
     misc_feature    96791..96802
                     /gene="mraY"
                     /locus_tag="b0087"
                     /gene_synonym="ECK0088; JW0085; murX"
                     /note="putative catalytic motif [active]"
                     /db_xref="CDD:133462"
     misc_feature    order(96950..96952,96968..96982)
                     /gene="mraY"
                     /locus_tag="b0087"
                     /gene_synonym="ECK0088; JW0085; murX"
                     /note="putative substrate binding site [chemical binding];
                     other site"
                     /db_xref="CDD:133462"
     gene            97087..98403
                     /gene="murD"
                     /locus_tag="b0088"
                     /gene_synonym="ECK0089; JW0086"
                     /db_xref="EcoGene:EG10620"
                     /db_xref="GeneID:944818"
     CDS             97087..98403
                     /gene="murD"
                     /locus_tag="b0088"
                     /gene_synonym="ECK0089; JW0086"
                     /EC_number="6.3.2.9"
                     /function="enzyme; Murein sacculus, peptidoglycan"
                     /GO_component="GO:0009274 - peptidoglycan-based cell wall"
                     /GO_component="GO:0005737 - cytoplasm"
                     /GO_process="GO:0009252 - peptidoglycan biosynthetic
                     process"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-L-alanine:D-glutamate
                     ligase"
                     /protein_id="NP_414630.1"
                     /db_xref="GI:16128081"
                     /db_xref="ASAP:ABE-0000318"
                     /db_xref="UniProtKB/Swiss-Prot:P14900"
                     /db_xref="EcoGene:EG10620"
                     /db_xref="GeneID:944818"
                     /translation="MADYQGKNVVIIGLGLTGLSCVDFFLARGVTPRVMDTRMTPPGL
                     DKLPEAVERHTGSLNDEWLMAADLIVASPGIALAHPSLSAAADAGIEIVGDIELFCRE
                     AQAPIVAITGSNGKSTVTTLVGEMAKAAGVNVGVGGNIGLPALMLLDDECELYVLELS
                     SFQLETTSSLQAVAATILNVTEDHMDRYPFGLQQYRAAKLRIYENAKVCVVNADDALT
                     MPIRGADERCVSFGVNMGDYHLNHQQGETWLRVKGEKVLNVKEMKLSGQHNYTNALAA
                     LALADAAGLPRASSLKALTTFTGLPHRFEVVLEHNGVRWINDSKATNVGSTEAALNGL
                     HVDGTLHLLLGGDGKSADFSPLARYLNGDNVRLYCFGRDGAQLAALRPEVAEQTETME
                     QAMRLLAPRVQPGDMVLLSPACASLDQFKNFEQRGNEFARLAKELG"
     misc_feature    97087..98400
                     /gene="murD"
                     /locus_tag="b0088"
                     /gene_synonym="ECK0089; JW0086"
                     /note="UDP-N-acetylmuramoyl-L-alanyl-D-glutamate
                     synthetase; Provisional; Region: murD; PRK03806"
                     /db_xref="CDD:179651"
     misc_feature    97414..97902
                     /gene="murD"
                     /locus_tag="b0088"
                     /gene_synonym="ECK0089; JW0086"
                     /note="Mur ligase middle domain; Region: Mur_ligase_M;
                     pfam08245"
                     /db_xref="CDD:254689"
     misc_feature    97987..98205
                     /gene="murD"
                     /locus_tag="b0088"
                     /gene_synonym="ECK0089; JW0086"
                     /note="Mur ligase family, glutamate ligase domain; Region:
                     Mur_ligase_C; pfam02875"
                     /db_xref="CDD:251584"
     gene            98403..99647
                     /gene="ftsW"
                     /locus_tag="b0089"
                     /gene_synonym="ECK0090; JW0087"
                     /db_xref="EcoGene:EG10344"
                     /db_xref="GeneID:946322"
     CDS             98403..99647
                     /gene="ftsW"
                     /locus_tag="b0089"
                     /gene_synonym="ECK0090; JW0087"
                     /function="membrane; Cell division"
                     /GO_component="GO:0009274 - peptidoglycan-based cell wall"
                     /GO_component="GO:0019866 - organelle inner membrane"
                     /note="cell division; membrane protein involved in shape
                     determination"
                     /codon_start=1
                     /transl_table=11
                     /product="putative lipid II flippase; integral membrane
                     protein; FtsZ ring stabilizer"
                     /protein_id="NP_414631.1"
                     /db_xref="GI:16128082"
                     /db_xref="ASAP:ABE-0000320"
                     /db_xref="UniProtKB/Swiss-Prot:P0ABG4"
                     /db_xref="EcoGene:EG10344"
                     /db_xref="GeneID:946322"
                     /translation="MRLSLPRLKMPRLPGFSILVWISTALKGWVMGSREKDTDSLIMY
                     DRTLLWLTFGLAAIGFIMVTSASMPIGQRLTNDPFFFAKRDGVYLILAFILAIITLRL
                     PMEFWQRYSATMLLGSIILLMIVLVVGSSVKGASRWIDLGLLRIQPAELTKLSLFCYI
                     ANYLVRKGDEVRNNLRGFLKPMGVILVLAVLLLAQPDLGTVVVLFVTTLAMLFLAGAK
                     LWQFIAIIGMGISAVVLLILAEPYRIRRVTAFWNPWEDPFGSGYQLTQSLMAFGRGEL
                     WGQGLGNSVQKLEYLPEAHTDFIFAIIGEELGYVGVVLALLMVFFVAFRAMSIGRKAL
                     EIDHRFSGFLACSIGIWFSFQALVNVGAAAGMLPTKGLTLPLISYGGSSLLIMSTAIM
                     MLLRIDYETRLEKAQAFVRGSR"
     misc_feature    98433..99644
                     /gene="ftsW"
                     /locus_tag="b0089"
                     /gene_synonym="ECK0090; JW0087"
                     /note="cell division protein FtsW; Provisional; Region:
                     PRK10774"
                     /db_xref="CDD:182719"
     gene            99644..100711
                     /gene="murG"
                     /locus_tag="b0090"
                     /gene_synonym="ECK0091; JW0088"
                     /db_xref="EcoGene:EG10623"
                     /db_xref="GeneID:946321"
     CDS             99644..100711
                     /gene="murG"
                     /locus_tag="b0090"
                     /gene_synonym="ECK0091; JW0088"
                     /EC_number="2.4.1.227"
                     /function="enzyme; Murein sacculus, peptidoglycan"
                     /GO_component="GO:0009274 - peptidoglycan-based cell wall"
                     /GO_component="GO:0019866 - organelle inner membrane"
                     /GO_process="GO:0009252 - peptidoglycan biosynthetic
                     process"
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylglucosaminyl transferase"
                     /protein_id="NP_414632.1"
                     /db_xref="GI:16128083"
                     /db_xref="ASAP:ABE-0000322"
                     /db_xref="UniProtKB/Swiss-Prot:P17443"
                     /db_xref="EcoGene:EG10623"
                     /db_xref="GeneID:946321"
                     /translation="MSGQGKRLMVMAGGTGGHVFPGLAVAHHLMAQGWQVRWLGTADR
                     MEADLVPKHGIEIDFIRISGLRGKGIKALIAAPLRIFNAWRQARAIMKAYKPDVVLGM
                     GGYVSGPGGLAAWSLGIPVVLHEQNGIAGLTNKWLAKIATKVMQAFPGAFPNAEVVGN
                     PVRTDVLALPLPQQRLAGREGPVRVLVVGGSQGARILNQTMPQVAAKLGDSVTIWHQS
                     GKGSQQSVEQAYAEAGQPQHKVTEFIDDMAAAYAWADVVVCRSGALTVSEIAAAGLPA
                     LFVPFQHKDRQQYWNALPLEKAGAAKIIEQPQLSVDAVANTLAGWSRETLLTMAERAR
                     AASIPDATERVANEVSRVARA"
     misc_feature    99659..100708
                     /gene="murG"
                     /locus_tag="b0090"
                     /gene_synonym="ECK0091; JW0088"
                     /note="undecaprenyldiphospho-muramoylpentapeptide beta-N-
                     acetylglucosaminyltransferase; Provisional; Region: murG;
                     PRK00726"
                     /db_xref="CDD:234825"
     misc_feature    99662..100687
                     /gene="murG"
                     /locus_tag="b0090"
                     /gene_synonym="ECK0091; JW0088"
                     /note="MurG is an N-acetylglucosaminyltransferase, the
                     last enzyme involved in the intracellular phase of
                     peptidoglycan biosynthesis. It transfers
                     N-acetyl-D-glucosamine (GlcNAc) from UDP-GlcNAc to the C4
                     hydroxyl of a lipid-linked N-acetylmuramoyl
                     pentapeptide...; Region: GT1_MurG; cd03785"
                     /db_xref="CDD:99961"
     misc_feature    order(99692..99694,100022..100024,100214..100216,
                     100292..100294,100370..100372,100382..100384,
                     100427..100438,100445..100447,100484..100486,
                     100502..100507,100514..100516)
                     /gene="murG"
                     /locus_tag="b0090"
                     /gene_synonym="ECK0091; JW0088"
                     /note="active site"
                     /db_xref="CDD:99961"
     misc_feature    order(99863..99865,99872..99874,99905..99907,99989..99991,
                     100064..100066)
                     /gene="murG"
                     /locus_tag="b0090"
                     /gene_synonym="ECK0091; JW0088"
                     /note="homodimer interface [polypeptide binding]; other
                     site"
                     /db_xref="CDD:99961"
     gene            100765..102240
                     /gene="murC"
                     /locus_tag="b0091"
                     /gene_synonym="ECK0092; JW0089"
                     /db_xref="EcoGene:EG10619"
                     /db_xref="GeneID:946153"
     CDS             100765..102240
                     /gene="murC"
                     /locus_tag="b0091"
                     /gene_synonym="ECK0092; JW0089"
                     /EC_number="6.3.2.8"
                     /function="enzyme; Murein sacculus, peptidoglycan"
                     /experiment="N-terminus verified by Edman degradation:
                     PMID 7601127"
                     /GO_component="GO:0009274 - peptidoglycan-based cell wall"
                     /GO_process="GO:0009252 - peptidoglycan biosynthetic
                     process"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramate:L-alanine ligase"
                     /protein_id="NP_414633.1"
                     /db_xref="GI:16128084"
                     /db_xref="ASAP:ABE-0000324"
                     /db_xref="UniProtKB/Swiss-Prot:P17952"
                     /db_xref="EcoGene:EG10619"
                     /db_xref="GeneID:946153"
                     /translation="MNTQQLAKLRSIVPEMRRVRHIHFVGIGGAGMGGIAEVLANEGY
                     QISGSDLAPNPVTQQLMNLGATIYFNHRPENVRDASVVVVSSAISADNPEIVAAHEAR
                     IPVIRRAEMLAELMRFRHGIAIAGTHGKTTTTAMVSSIYAEAGLDPTFVNGGLVKAAG
                     VHARLGHGRYLIAEADESDASFLHLQPMVAIVTNIEADHMDTYQGDFENLKQTFINFL
                     HNLPFYGRAVMCVDDPVIRELLPRVGRQTTTYGFSEDADVRVEDYQQIGPQGHFTLLR
                     QDKEPMRVTLNAPGRHNALNAAAAVAVATEEGIDDEAILRALESFQGTGRRFDFLGEF
                     PLEPVNGKSGTAMLVDDYGHHPTEVDATIKAARAGWPDKNLVMLFQPHRFTRTRDLYD
                     DFANVLTQVDTLLMLEVYPAGEAPIPGADSRSLCRTIRGRGKIDPILVPDPARVAEML
                     APVLTGNDLILVQGAGNIGKIARSLAEIKLKPQTPEEEQHD"
     misc_feature    100801..102216
                     /gene="murC"
                     /locus_tag="b0091"
                     /gene_synonym="ECK0092; JW0089"
                     /note="UDP-N-acetylmuramate--L-alanine ligase;
                     Provisional; Region: murC; PRK00421"
                     /db_xref="CDD:234757"
     misc_feature    100825..101124
                     /gene="murC"
                     /locus_tag="b0091"
                     /gene_synonym="ECK0092; JW0089"
                     /note="Mur ligase family, catalytic domain; Region:
                     Mur_ligase; pfam01225"
                     /db_xref="CDD:250458"
     misc_feature    101134..101649
                     /gene="murC"
                     /locus_tag="b0091"
                     /gene_synonym="ECK0092; JW0089"
                     /note="Mur ligase middle domain; Region: Mur_ligase_M;
                     pfam08245"
                     /db_xref="CDD:254689"
     misc_feature    101770..102024
                     /gene="murC"
                     /locus_tag="b0091"
                     /gene_synonym="ECK0092; JW0089"
                     /note="Mur ligase family, glutamate ligase domain; Region:
                     Mur_ligase_C; pfam02875"
                     /db_xref="CDD:251584"
     gene            102233..103153
                     /gene="ddlB"
                     /locus_tag="b0092"
                     /gene_synonym="ddl; ECK0093; JW0090"
                     /db_xref="EcoGene:EG10214"
                     /db_xref="GeneID:946324"
     CDS             102233..103153
                     /gene="ddlB"
                     /locus_tag="b0092"
                     /gene_synonym="ddl; ECK0093; JW0090"
                     /EC_number="6.3.2.4"
                     /function="enzyme; Murein sacculus, peptidoglycan"
                     /GO_component="GO:0009274 - peptidoglycan-based cell wall"
                     /GO_component="GO:0005737 - cytoplasm"
                     /GO_process="GO:0009252 - peptidoglycan biosynthetic
                     process"
                     /note="D-alanine-D-alanine ligase B, affects cell
                     division"
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine:D-alanine ligase"
                     /protein_id="NP_414634.1"
                     /db_xref="GI:16128085"
                     /db_xref="ASAP:ABE-0000326"
                     /db_xref="UniProtKB/Swiss-Prot:P07862"
                     /db_xref="EcoGene:EG10214"
                     /db_xref="GeneID:946324"
                     /translation="MTDKIAVLLGGTSAEREVSLNSGAAVLAGLREGGIDAYPVDPKE
                     VDVTQLKSMGFQKVFIALHGRGGEDGTLQGMLELMGLPYTGSGVMASALSMDKLRSKL
                     LWQGAGLPVAPWVALTRAEFEKGLSDKQLAEISALGLPVIVKPSREGSSVGMSKVVAE
                     NALQDALRLAFQHDEEVLIEKWLSGPEFTVAILGEEILPSIRIQPSGTFYDYEAKYLS
                     DETQYFCPAGLEASQEANLQALVLKAWTTLGCKGWGRIDVMLDSDGQFYLLEANTSPG
                     MTSHSLVPMAARQAGMSFSQLVVRILELAD"
     misc_feature    102233..103150
                     /gene="ddlB"
                     /locus_tag="b0092"
                     /gene_synonym="ddl; ECK0093; JW0090"
                     /note="D-alanine--D-alanine ligase; Reviewed; Region: ddl;
                     PRK01372"
                     /db_xref="CDD:234948"
     misc_feature    102242..102490
                     /gene="ddlB"
                     /locus_tag="b0092"
                     /gene_synonym="ddl; ECK0093; JW0090"
                     /note="D-ala D-ala ligase N-terminus; Region:
                     Dala_Dala_lig_N; pfam01820"
                     /db_xref="CDD:250892"
     misc_feature    102539..103141
                     /gene="ddlB"
                     /locus_tag="b0092"
                     /gene_synonym="ddl; ECK0093; JW0090"
                     /note="D-ala D-ala ligase C-terminus; Region:
                     Dala_Dala_lig_C; pfam07478"
                     /db_xref="CDD:254223"
     gene            103155..103985
                     /gene="ftsQ"
                     /locus_tag="b0093"
                     /gene_synonym="ECK0094; JW0091"
                     /db_xref="EcoGene:EG10342"
                     /db_xref="GeneID:944823"
     CDS             103155..103985
                     /gene="ftsQ"
                     /locus_tag="b0093"
                     /gene_synonym="ECK0094; JW0091"
                     /function="phenotype; Cell division"
                     /GO_component="GO:0019866 - organelle inner membrane"
                     /note="cell division protein; ingrowth of wall at septum"
                     /codon_start=1
                     /transl_table=11
                     /product="divisome assembly protein, membrane anchored
                     protein involved in growth of wall at septum"
                     /protein_id="NP_414635.1"
                     /db_xref="GI:16128086"
                     /db_xref="ASAP:ABE-0000329"
                     /db_xref="UniProtKB/Swiss-Prot:P06136"
                     /db_xref="EcoGene:EG10342"
                     /db_xref="GeneID:944823"
                     /translation="MSQAALNTRNSEEEVSSRRNNGTRLAGILFLLTVLTTVLVSGWV
                     VLGWMEDAQRLPLSKLVLTGERHYTRNDDIRQSILALGEPGTFMTQDVNIIQTQIEQR
                     LPWIKQVSVRKQWPDELKIHLVEYVPIARWNDQHMVDAEGNTFSVPPERTSKQVLPML
                     YGPEGSANEVLQGYREMGQMLAKDRFTLKEAAMTARRSWQLTLNNDIKLNLGRGDTMK
                     RLARFVELYPVLQQQAQTDGKRISYVDLRYDSGAAVGWAPLPPEESTQQQNQAQAEQQ
                     "
     misc_feature    103155..103946
                     /gene="ftsQ"
                     /locus_tag="b0093"
                     /gene_synonym="ECK0094; JW0091"
                     /note="cell division protein FtsQ; Provisional; Region:
                     PRK10775"
                     /db_xref="CDD:182720"
     misc_feature    103323..103532
                     /gene="ftsQ"
                     /locus_tag="b0093"
                     /gene_synonym="ECK0094; JW0091"
                     /note="POTRA domain, FtsQ-type; Region: POTRA_1;
                     pfam08478"
                     /db_xref="CDD:254821"
     misc_feature    103539..103895
                     /gene="ftsQ"
                     /locus_tag="b0093"
                     /gene_synonym="ECK0094; JW0091"
                     /note="Cell division protein FtsQ; Region: FtsQ;
                     pfam03799"
                     /db_xref="CDD:252171"
     gene            103982..105244
                     /gene="ftsA"
                     /locus_tag="b0094"
                     /gene_synonym="divA; ECK0095; JW0092"
                     /db_xref="EcoGene:EG10339"
                     /db_xref="GeneID:944778"
     CDS             103982..105244
                     /gene="ftsA"
                     /locus_tag="b0094"
                     /gene_synonym="divA; ECK0095; JW0092"
                     /function="phenotype; Cell division"
                     /GO_component="GO:0009274 - peptidoglycan-based cell wall"
                     /GO_component="GO:0019866 - organelle inner membrane"
                     /note="ATP-binding cell division protein, septation
                     process, complexes with FtsZ, associated with junctions of
                     inner and outer membranes"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cell division FtsK recruitment
                     protein"
                     /protein_id="NP_414636.1"
                     /db_xref="GI:16128087"
                     /db_xref="ASAP:ABE-0000331"
                     /db_xref="UniProtKB/Swiss-Prot:P0ABH0"
                     /db_xref="EcoGene:EG10339"
                     /db_xref="GeneID:944778"
                     /translation="MIKATDRKLVVGLEIGTAKVAALVGEVLPDGMVNIIGVGSCPSR
                     GMDKGGVNDLESVVKCVQRAIDQAELMADCQISSVYLALSGKHISCQNEIGMVPISEE
                     EVTQEDVENVVHTAKSVRVRDEHRVLHVIPQEYAIDYQEGIKNPVGLSGVRMQAKVHL
                     ITCHNDMAKNIVKAVERCGLKVDQLIFAGLASSYSVLTEDERELGVCVVDIGGGTMDI
                     AVYTGGALRHTKVIPYAGNVVTSDIAYAFGTPPSDAEAIKVRHGCALGSIVGKDESVE
                     VPSVGGRPPRSLQRQTLAEVIEPRYTELLNLVNEEILQLQEKLRQQGVKHHLAAGIVL
                     TGGAAQIEGLAACAQRVFHTQVRIGAPLNITGLTDYAQEPYYSTAVGLLHYGKESHLN
                     GEAEVEKRVTASVGSWIKRLNSWLRKEF"
     misc_feature    103982..105241
                     /gene="ftsA"
                     /locus_tag="b0094"
                     /gene_synonym="divA; ECK0095; JW0092"
                     /note="cell division protein FtsA; Reviewed; Region: ftsA;
                     PRK09472"
                     /db_xref="CDD:181887"
     misc_feature    104009..104545
                     /gene="ftsA"
                     /locus_tag="b0094"
                     /gene_synonym="divA; ECK0095; JW0092"
                     /note="Cell division protein FtsA; Region: FtsA;
                     pfam14450"
                     /db_xref="CDD:258601"
     misc_feature    104282..>104665
                     /gene="ftsA"
                     /locus_tag="b0094"
                     /gene_synonym="divA; ECK0095; JW0092"
                     /note="Nucleotide-Binding Domain of the sugar
                     kinase/HSP70/actin superfamily; Region:
                     NBD_sugar-kinase_HSP70_actin; cd00012"
                     /db_xref="CDD:212657"
     misc_feature    104597..105058
                     /gene="ftsA"
                     /locus_tag="b0094"
                     /gene_synonym="divA; ECK0095; JW0092"
                     /note="Cell division protein FtsA; Region: FtsA;
                     pfam14450"
                     /db_xref="CDD:258601"
     STS             104533..104769
                     /gene="ftsA"
                     /locus_tag="b0094"
                     /gene_synonym="divA; ECK0095; JW0092"
                     /standard_name="G34047"
                     /db_xref="UniSTS:10389"
     gene            105305..106456
                     /gene="ftsZ"
                     /locus_tag="b0095"
                     /gene_synonym="ECK0096; JW0093; sfiB; sulB"
                     /db_xref="EcoGene:EG10347"
                     /db_xref="GeneID:944786"
     CDS             105305..106456
                     /gene="ftsZ"
                     /locus_tag="b0095"
                     /gene_synonym="ECK0096; JW0093; sfiB; sulB"
                     /function="enzyme; Cell division"
                     /experiment="N-terminus verified by Edman degradation:
                     PMID 9298646"
                     /GO_component="GO:0005737 - cytoplasm"
                     /note="cell division; forms circumferential ring;
                     tubulin-like GTP-binding protein and GTPase"
                     /codon_start=1
                     /transl_table=11
                     /product="GTP-binding tubulin-like cell division protein"
                     /protein_id="NP_414637.1"
                     /db_xref="GI:16128088"
                     /db_xref="ASAP:ABE-0000333"
                     /db_xref="UniProtKB/Swiss-Prot:P0A9A6"
                     /db_xref="EcoGene:EG10347"
                     /db_xref="GeneID:944786"
                     /translation="MFEPMELTNDAVIKVIGVGGGGGNAVEHMVRERIEGVEFFAVNT
                     DAQALRKTAVGQTIQIGSGITKGLGAGANPEVGRNAADEDRDALRAALEGADMVFIAA
                     GMGGGTGTGAAPVVAEVAKDLGILTVAVVTKPFNFEGKKRMAFAEQGITELSKHVDSL
                     ITIPNDKLLKVLGRGISLLDAFGAANDVLKGAVQGIAELITRPGLMNVDFADVRTVMS
                     EMGYAMMGSGVASGEDRAEEAAEMAISSPLLEDIDLSGARGVLVNITAGFDLRLDEFE
                     TVGNTIRAFASDNATVVIGTSLDPDMNDELRVTVVATGIGMDKRPEITLVTNKQVQQP
                     VMDRYQQHGMAPLTQEQKPVAKVVNDNAPQTAKEPDYLDIPAFLRKQAD"
     misc_feature    105374..106453
                     /gene="ftsZ"
                     /locus_tag="b0095"
                     /gene_synonym="ECK0096; JW0093; sfiB; sulB"
                     /note="cell division protein FtsZ; Validated; Region:
                     PRK09330"
                     /db_xref="CDD:236468"
     misc_feature    105374..106246
                     /gene="ftsZ"
                     /locus_tag="b0095"
                     /gene_synonym="ECK0096; JW0093; sfiB; sulB"
                     /note="FtsZ is a GTPase that is similar to the eukaryotic
                     tubulins and is essential for cell division in
                     prokaryotes.  FtsZ is capable of polymerizing in a
                     GTP-driven process into structures similar to those formed
                     by tubulin. FtsZ forms a ring-shaped septum at...; Region:
                     FtsZ_type1; cd02201"
                     /db_xref="CDD:100021"
     misc_feature    order(105374..105376,105446..105448,105611..105631,
                     105704..105709,105728..105730,105797..105799,
                     105848..105850,105857..105862,105869..105871)
                     /gene="ftsZ"
                     /locus_tag="b0095"
                     /gene_synonym="ECK0096; JW0093; sfiB; sulB"
                     /note="nucleotide binding site [chemical binding]; other
                     site"
                     /db_xref="CDD:100021"
     misc_feature    order(105920..105925,105929..105931,106109..106120,
                     106127..106129)
                     /gene="ftsZ"
                     /locus_tag="b0095"
                     /gene_synonym="ECK0096; JW0093; sfiB; sulB"
                     /note="SulA interaction site; other site"
                     /db_xref="CDD:100021"
     misc_feature    <106322..106453
                     /gene="ftsZ"
                     /locus_tag="b0095"
                     /gene_synonym="ECK0096; JW0093; sfiB; sulB"
                     /note="cell division protein FtsZ, alphaProteobacterial
                     C-terminal extension; Region: FtsZ_alphas_C; TIGR03483"
                     /db_xref="CDD:234228"
     gene            106557..107474
                     /gene="lpxC"
                     /locus_tag="b0096"
                     /gene_synonym="asmB; ECK0097; envA; JW0094"
                     /db_xref="EcoGene:EG10265"
                     /db_xref="GeneID:944816"
     CDS             106557..107474
                     /gene="lpxC"
                     /locus_tag="b0096"
                     /gene_synonym="asmB; ECK0097; envA; JW0094"
                     /EC_number="3.5.1.-"
                     /function="enzyme; Surface polysaccharides & antigens"
                     /experiment="N-terminus verified by Edman degradation:
                     PMID 8530464"
                     /GO_component="GO:0009274 - peptidoglycan-based cell wall"
                     /GO_component="GO:0005737 - cytoplasm"
                     /GO_function="GO:0042280 - cell surface antigen activity,
                     host-interacting"
                     /GO_process="GO:0009245 - lipid A biosynthetic process"
                     /note="UDP-3-O-acyl N-acetylglucosamine deacetylase; lipid
                     A biosynthesis"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-3-O-acyl N-acetylglucosamine deacetylase"
                     /protein_id="NP_414638.1"
                     /db_xref="GI:16128089"
                     /db_xref="ASAP:ABE-0000336"
                     /db_xref="UniProtKB/Swiss-Prot:P0A725"
                     /db_xref="EcoGene:EG10265"
                     /db_xref="GeneID:944816"
                     /translation="MIKQRTLKRIVQATGVGLHTGKKVTLTLRPAPANTGVIYRRTDL
                     NPPVDFPADAKSVRDTMLCTCLVNEHDVRISTVEHLNAALAGLGIDNIVIEVNAPEIP
                     IMDGSAAPFVYLLLDAGIDELNCAKKFVRIKETVRVEDGDKWAEFKPYNGFSLDFTID
                     FNHPAIDSSNQRYAMNFSADAFMRQISRARTFGFMRDIEYLQSRGLCLGGSFDCAIVV
                     DDYRVLNEDGLRFEDEFVRHKMLDAIGDLFMCGHNIIGAFTAYKSGHALNNKLLQAVL
                     AKQEAWEYVTFQDDAELPLAFKAPSAVLA"
     misc_feature    106557..107453
                     /gene="lpxC"
                     /locus_tag="b0096"
                     /gene_synonym="asmB; ECK0097; envA; JW0094"
                     /note="UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine
                     deacetylase; Reviewed; Region: lpxC; PRK13186"
                     /db_xref="CDD:237294"
     misc_feature    106560..107396
                     /gene="lpxC"
                     /locus_tag="b0096"
                     /gene_synonym="asmB; ECK0097; envA; JW0094"
                     /note="UDP-3-O-acyl N-acetylglycosamine deacetylase;
                     Region: LpxC; pfam03331"
                     /db_xref="CDD:202596"
     gene            107705..108217
                     /gene="secM"
                     /locus_tag="b0097"
                     /gene_synonym="ECK0098; JW5007; srrA; yacA"
                     /db_xref="EcoGene:EG11087"
                     /db_xref="GeneID:944831"
     CDS             107705..108217
                     /gene="secM"
                     /locus_tag="b0097"
                     /gene_synonym="ECK0098; JW5007; srrA; yacA"
                     /codon_start=1
                     /transl_table=11
                     /product="regulator of secA translation"
                     /protein_id="NP_414639.2"
                     /db_xref="GI:90111085"
                     /db_xref="ASAP:ABE-0000340"
                     /db_xref="UniProtKB/Swiss-Prot:P62395"
                     /db_xref="EcoGene:EG11087"
                     /db_xref="GeneID:944831"
                     /translation="MSGILTRWRQFGKRYFWPHLLLGMVAASLGLPALSNAAEPNAPA
                     KATTRNHEPSAKVNFGQLALLEANTRRPNSNYSVDYWHQHAIRTVIRHLSFAMAPQTL
                     PVAEESLPLQAQHLALLDTLSALLTQEGTPSEKGYRIDYAHFTPQAKFSTPVWISQAQ
                     GIRAGPQRLT"
     misc_feature    107708..108211
                     /gene="secM"
                     /locus_tag="b0097"
                     /gene_synonym="ECK0098; JW5007; srrA; yacA"
                     /note="SecA regulator SecM; Provisional; Region: PRK02943"
                     /db_xref="CDD:235088"
     gene            108279..110984
                     /gene="secA"
                     /locus_tag="b0098"
                     /gene_synonym="azi; ECK0099; JW0096; pea; prlD"
                     /db_xref="EcoGene:EG10936"
                     /db_xref="GeneID:944821"
     CDS             108279..110984
                     /gene="secA"
                     /locus_tag="b0098"
                     /gene_synonym="azi; ECK0099; JW0096; pea; prlD"
                     /function="transport; Protein, peptide secretion"
                     /experiment="N-terminus verified by Edman degradation:
                     PMID 2841285"
                     /GO_component="GO:0005737 - cytoplasm"
                     /note="preprotein translocase; secretion protein"
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit, ATPase"
                     /protein_id="NP_414640.1"
                     /db_xref="GI:16128091"
                     /db_xref="ASAP:ABE-0000343"
                     /db_xref="UniProtKB/Swiss-Prot:P10408"
                     /db_xref="EcoGene:EG10936"
                     /db_xref="GeneID:944821"
                     /translation="MLIKLLTKVFGSRNDRTLRRMRKVVNIINAMEPEMEKLSDEELK
                     GKTAEFRARLEKGEVLENLIPEAFAVVREASKRVFGMRHFDVQLLGGMVLNERCIAEM
                     RTGEGKTLTATLPAYLNALTGKGVHVVTVNDYLAQRDAENNRPLFEFLGLTVGINLPG
                     MPAPAKREAYAADITYGTNNEYGFDYLRDNMAFSPEERVQRKLHYALVDEVDSILIDE
                     ARTPLIISGPAEDSSEMYKRVNKIIPHLIRQEKEDSETFQGEGHFSVDEKSRQVNLTE
                     RGLVLIEELLVKEGIMDEGESLYSPANIMLMHHVTAALRAHALFTRDVDYIVKDGEVI
                     IVDEHTGRTMQGRRWSDGLHQAVEAKEGVQIQNENQTLASITFQNYFRLYEKLAGMTG
                     TADTEAFEFSSIYKLDTVVVPTNRPMIRKDLPDLVYMTEAEKIQAIIEDIKERTAKGQ
                     PVLVGTISIEKSELVSNELTKAGIKHNVLNAKFHANEAAIVAQAGYPAAVTIATNMAG
                     RGTDIVLGGSWQAEVAALENPTAEQIEKIKADWQVRHDAVLEAGGLHIIGTERHESRR
                     IDNQLRGRSGRQGDAGSSRFYLSMEDALMRIFASDRVSGMMRKLGMKPGEAIEHPWVT
                     KAIANAQRKVESRNFDIRKQLLEYDDVANDQRRAIYSQRNELLDVSDVSETINSIRED
                     VFKATIDAYIPPQSLEEMWDIPGLQERLKNDFDLDLPIAEWLDKEPELHEETLRERIL
                     AQSIEVYQRKEEVVGAEMMRHFEKGVMLQTLDSLWKEHLAAMDYLRQGIHLRGYAQKD
                     PKQEYKRESFSMFAAMLESLKYEVISTLSKVQVRMPEEVEELEQQRRMEAERLAQMQQ
                     LSHQDDDSAAAAALAAQTGERKVGRNDPCPCGSGKKYKQCHGRLQ"
     misc_feature    108282..110981
                     /gene="secA"
                     /locus_tag="b0098"
                     /gene_synonym="azi; ECK0099; JW0096; pea; prlD"
                     /note="preprotein translocase subunit SecA; Reviewed;
                     Region: PRK12904"
                     /db_xref="CDD:237259"
     misc_feature    108960..109352
                     /gene="secA"
                     /locus_tag="b0098"
                     /gene_synonym="azi; ECK0099; JW0096; pea; prlD"
                     /note="SecA preprotein cross-linking domain; Region:
                     SecA_PP_bind; smart00958"
                     /db_xref="CDD:214938"
     misc_feature    110127..110771
                     /gene="secA"
                     /locus_tag="b0098"
                     /gene_synonym="azi; ECK0099; JW0096; pea; prlD"
                     /note="SecA Wing and Scaffold domain; Region: SecA_SW;
                     pfam07516"
                     /db_xref="CDD:254253"
     misc_feature    110919..110975
                     /gene="secA"
                     /locus_tag="b0098"
                     /gene_synonym="azi; ECK0099; JW0096; pea; prlD"
                     /note="SEC-C motif; Region: SEC-C; pfam02810"
                     /db_xref="CDD:251544"
     gene            111044..111433
                     /gene="mutT"
                     /locus_tag="b0099"
                     /gene_synonym="ECK0100; JW0097; nudA"
                     /db_xref="EcoGene:EG10626"
                     /db_xref="GeneID:944824"
     CDS             111044..111433
                     /gene="mutT"
                     /locus_tag="b0099"
                     /gene_synonym="ECK0100; JW0097; nudA"
                     /EC_number="3.6.1.-"
                     /function="enzyme; 2'-Deoxyribonucleotide metabolism"
                     /experiment="N-terminus verified by Edman degradation:
                     PMID 3288626"
                     /GO_component="GO:0005737 - cytoplasm"
                     /note="7,8-dihydro-8-oxoguanine-triphosphatase, prefers
                     dGTP, causes AT-GC transversions"
                     /codon_start=1
                     /transl_table=11
                     /product="dGTP-preferring nucleoside triphosphate
                     pyrophosphohydrolase"
                     /protein_id="NP_414641.1"
                     /db_xref="GI:16128092"
                     /db_xref="ASAP:ABE-0000346"
                     /db_xref="UniProtKB/Swiss-Prot:P08337"
                     /db_xref="EcoGene:EG10626"
                     /db_xref="GeneID:944824"
                     /translation="MKKLQIAVGIIRNENNEIFITRRAADAHMANKLEFPGGKIEMGE
                     TPEQAVVRELQEEVGITPQHFSLFEKLEYEFPDRHITLWFWLVERWEGEPWGKEGQPG
                     EWMSLVGLNADDFPPANEPVIAKLKRL"
     misc_feature    111053..111424
                     /gene="mutT"
                     /locus_tag="b0099"
                     /gene_synonym="ECK0100; JW0097; nudA"
                     /note="The MutT pyrophosphohydrolase is a prototypical
                     Nudix hydrolase that catalyzes the hydrolysis of
                     nucleoside and deoxynucleoside triphosphates (NTPs and
                     dNTPs) by substitution at a beta-phosphorus to yield a
                     nucleotide monophosphate (NMP) and inorganic...; Region:
                     MutT_pyrophosphohydrolase; cd03425"
                     /db_xref="CDD:239517"
     misc_feature    order(111053..111055,111059..111061,111155..111160,
                     111164..111166,111200..111202,111209..111214,
                     111281..111283,111335..111337,111398..111400)
                     /gene="mutT"
                     /locus_tag="b0099"
                     /gene_synonym="ECK0100; JW0097; nudA"
                     /note="active site"
                     /db_xref="CDD:239517"
     misc_feature    order(111053..111055,111059..111061,111155..111160,
                     111275..111277,111281..111283,111398..111400)
                     /gene="mutT"
                     /locus_tag="b0099"
                     /gene_synonym="ECK0100; JW0097; nudA"
                     /note="8-oxo-dGMP binding site [chemical binding]; other
                     site"
                     /db_xref="CDD:239517"
     misc_feature    111155..111223
                     /gene="mutT"
                     /locus_tag="b0099"
                     /gene_synonym="ECK0100; JW0097; nudA"
                     /note="nudix motif; other site"
                     /db_xref="CDD:239517"
     misc_feature    order(111200..111202,111209..111214)
                     /gene="mutT"
                     /locus_tag="b0099"
                     /gene_synonym="ECK0100; JW0097; nudA"
                     /note="metal binding site [ion binding]; metal-binding
                     site"
                     /db_xref="CDD:239517"
     repeat_region   111430..111629
                     /note="RIP8 (repetitive extragenic palindromic) element;
                     contains 4 REP sequences and 1 IHF site"
     gene            complement(111649..111846)
                     /gene="yacG"
                     /locus_tag="b0101"
                     /gene_synonym="ECK0101; JW5008"
                     /db_xref="EcoGene:EG12314"
                     /db_xref="GeneID:945630"
     CDS             complement(111649..111846)
                     /gene="yacG"
                     /locus_tag="b0101"
                     /gene_synonym="ECK0101; JW5008"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA gyrase inhibitor"
                     /protein_id="NP_414643.1"
                     /db_xref="GI:16128094"
                     /db_xref="ASAP:ABE-0000351"
                     /db_xref="UniProtKB/Swiss-Prot:P0A8H8"
                     /db_xref="EcoGene:EG12314"
                     /db_xref="GeneID:945630"
                     /translation="MSETITVNCPTCGKTVVWGEISPFRPFCSKRCQLIDLGEWAAEE
                     KRIPSSGDLSESDDWSEEPKQ"
     misc_feature    complement(111661..111846)
                     /gene="yacG"
                     /locus_tag="b0101"
                     /gene_synonym="ECK0101; JW5008"
                     /note="DNA gyrase inhibitor; Reviewed; Region: PRK00418"
                     /db_xref="CDD:234754"
     gene            complement(111856..112599)
                     /gene="zapD"
                     /locus_tag="b0102"
                     /gene_synonym="ECK0102; JW0099; yacF"
                     /db_xref="EcoGene:EG12313"
                     /db_xref="GeneID:944873"
     CDS             complement(111856..112599)
                     /gene="zapD"
                     /locus_tag="b0102"
                     /gene_synonym="ECK0102; JW0099; yacF"
                     /codon_start=1
                     /transl_table=11
                     /product="FtsZ stabilizer"
                     /protein_id="NP_414644.1"
                     /db_xref="GI:16128095"
                     /db_xref="ASAP:ABE-0000355"
                     /db_xref="UniProtKB/Swiss-Prot:P36680"
                     /db_xref="EcoGene:EG12313"
                     /db_xref="GeneID:944873"
                     /translation="MQTQVLFEHPLNEKMRTWLRIEFLIQQLTVNLPIVDHAGALHFF
                     RNVSELLDVFERGEVRTELLKELDRQQRKLQTWIGVPGVDQSRIEALIQQLKAAGSVL
                     ISAPRIGQFLREDRLIALVRQRLSIPGGCCSFDLPTLHIWLHLPQAQRDSQVETWIAS
                     LNPLTQALTMVLDLIRQSAPFRKQTSLNGFYQDNGGDADLLRLNLSLDSQLYPQISGH
                     KSRFAIRFMPLDTENGQVPERLDFELACC"
     misc_feature    complement(111859..112590)
                     /gene="zapD"
                     /locus_tag="b0102"
                     /gene_synonym="ECK0102; JW0099; yacF"
                     /note="Uncharacterized protein conserved in bacteria
                     [Function unknown]; Region: COG4582"
                     /db_xref="CDD:226948"
     gene            complement(112599..113219)
                     /gene="coaE"
                     /locus_tag="b0103"
                     /gene_synonym="ECK0103; JW0100; yacE"
                     /db_xref="EcoGene:EG12312"
                     /db_xref="GeneID:949060"
     CDS             complement(112599..113219)
                     /gene="coaE"
                     /locus_tag="b0103"
                     /gene_synonym="ECK0103; JW0100; yacE"
                     /EC_number="2.7.1.24"
                     /function="orf; Not classified"
                     /note="putative DNA repair protein"
                     /codon_start=1
                     /transl_table=11
                     /product="dephospho-CoA kinase"
                     /protein_id="NP_414645.1"
                     /db_xref="GI:16128096"
                     /db_xref="ASAP:ABE-0000357"
                     /db_xref="UniProtKB/Swiss-Prot:P0A6I9"
                     /db_xref="EcoGene:EG12312"
                     /db_xref="GeneID:949060"
                     /translation="MRYIVALTGGIGSGKSTVANAFADLGINVIDADIIARQVVEPGA
                     PALHAIADHFGANMIAADGTLQRRALRERIFANPEEKNWLNALLHPLIQQETQHQIQQ
                     ATSPYVLWVVPLLVENSLYKKANRVLVVDVSPETQLKRTMQRDDVTREHVEQILAAQA
                     TREARLAVADDVIDNNGAPDAIASDVARLHAHYLQLASQFVSQEKP"
     misc_feature    complement(112617..113219)
                     /gene="coaE"
                     /locus_tag="b0103"
                     /gene_synonym="ECK0103; JW0100; yacE"
                     /note="Dephospho-CoA kinase [Coenzyme metabolism]; Region:
                     CoaE; COG0237"
                     /db_xref="CDD:223315"
     misc_feature    complement(112677..113210)
                     /gene="coaE"
                     /locus_tag="b0103"
                     /gene_synonym="ECK0103; JW0100; yacE"
                     /note="Dephospho-coenzyme A kinase (DPCK, EC 2.7.1.24)
                     catalyzes the phosphorylation of dephosphocoenzyme A
                     (dCoA) to yield CoA, which is the final step in CoA
                     biosynthesis; Region: DPCK; cd02022"
                     /db_xref="CDD:238980"
     misc_feature    complement(order(112743..112745,112878..112883,
                     112953..112955,113121..113123,113196..113198))
                     /gene="coaE"
                     /locus_tag="b0103"
                     /gene_synonym="ECK0103; JW0100; yacE"
                     /note="CoA-binding site [chemical binding]; other site"
                     /db_xref="CDD:238980"
     misc_feature    complement(order(112695..112697,112800..112802,
                     113175..113180,113187..113195))
                     /gene="coaE"
                     /locus_tag="b0103"
                     /gene_synonym="ECK0103; JW0100; yacE"
                     /note="ATP-binding [chemical binding]; other site"
                     /db_xref="CDD:238980"
     gene            113444..114487
                     /gene="guaC"
                     /locus_tag="b0104"
                     /gene_synonym="ECK0104; JW0101"
                     /db_xref="EcoGene:EG10422"
                     /db_xref="GeneID:948986"
     CDS             113444..114487
                     /gene="guaC"
                     /locus_tag="b0104"
                     /gene_synonym="ECK0104; JW0101"
                     /EC_number="1.7.1.7"
                     /function="enzyme; Purine ribonucleotide biosynthesis"
                     /experiment="N-terminus verified by Edman degradation:
                     PMID 9298646"
                     /GO_component="GO:0005737 - cytoplasm"
                     /GO_process="GO:0009152 - purine ribonucleotide
                     biosynthetic process"
                     /GO_process="GO:0015949 - nucleobase, nucleoside and
                     nucleotide interconversion"
                     /codon_start=1
                     /transl_table=11
                     /product="GMP reductase"
                     /protein_id="NP_414646.1"
                     /db_xref="GI:16128097"
                     /db_xref="ASAP:ABE-0000362"
                     /db_xref="UniProtKB/Swiss-Prot:P60560"
                     /db_xref="EcoGene:EG10422"
                     /db_xref="GeneID:948986"
                     /translation="MRIEEDLKLGFKDVLIRPKRSTLKSRSDVELERQFTFKHSGQSW
                     SGVPIIAANMDTVGTFSMASALASFDILTAVHKHYSVEEWQAFINNSSADVLKHVMVS
                     TGTSDADFEKTKQILDLNPALNFVCIDVANGYSEHFVQFVAKAREAWPTKTICAGNVV
                     TGEMCEELILSGADIVKVGIGPGSVCTTRVKTGVGYPQLSAVIECADAAHGLGGMIVS
                     DGGCTTPGDVAKAFGGGADFVMLGGMLAGHEESGGRIVEENGEKFMLFYGMSSESAMK
                     RHVGGVAEYRAAEGKTVKLPLRGPVENTARDILGGLRSACTYVGASRLKELTKRTTFI
                     RVQEQENRIFNNL"
     misc_feature    113444..114481
                     /gene="guaC"
                     /locus_tag="b0104"
                     /gene_synonym="ECK0104; JW0101"
                     /note="guanosine 5'-monophosphate oxidoreductase;
                     Provisional; Region: PRK05096"
                     /db_xref="CDD:235343"
     misc_feature    113468..114451
                     /gene="guaC"
                     /locus_tag="b0104"
                     /gene_synonym="ECK0104; JW0101"
                     /note="IMPDH: The catalytic domain of the inosine
                     monophosphate dehydrogenase. IMPDH catalyzes the
                     NAD-dependent oxidation of inosine 5'-monophosphate (IMP)
                     to xanthosine 5' monophosphate (XMP). It is a
                     rate-limiting step in the de novo synthesis of...; Region:
                     IMPDH; cd00381"
                     /db_xref="CDD:238223"
     misc_feature    order(113597..113599,113993..114001,114098..114100,
                     114104..114106,114167..114172,114239..114241,
                     114245..114253,114308..114313)
                     /gene="guaC"
                     /locus_tag="b0104"
                     /gene_synonym="ECK0104; JW0101"
                     /note="active site"
                     /db_xref="CDD:238223"
     gene            complement(114522..115724)
                     /gene="hofC"
                     /locus_tag="b0106"
                     /gene_synonym="ECK0105; hopC; JW0102; yacD"
                     /db_xref="EcoGene:EG11798"
                     /db_xref="GeneID:945806"
     CDS             complement(114522..115724)
                     /gene="hofC"
                     /locus_tag="b0106"
                     /gene_synonym="ECK0105; hopC; JW0102; yacD"
                     /function="putative transport; Not classified"
                     /GO_component="GO:0009274 - peptidoglycan-based cell wall"
                     /GO_component="GO:0019866 - organelle inner membrane"
                     /note="putative integral membrane protein involved in
                     biogenesis of fimbriae, protein transport, DNA uptake"
                     /codon_start=1
                     /transl_table=11
                     /product="assembly protein in type IV pilin biogenesis,
                     transmembrane protein"
                     /protein_id="NP_414648.1"
                     /db_xref="GI:16128099"
                     /db_xref="ASAP:ABE-0000366"
                     /db_xref="UniProtKB/Swiss-Prot:P36646"
                     /db_xref="EcoGene:EG11798"
                     /db_xref="GeneID:945806"
                     /translation="MASKQLWRWHGITGDGNAQDGMLWAESRTLLLMALQQQMVTPLS
                     LKRIAINSAQWRGDKSAEVIHQLATLLKAGLTLSEGLALLAEQHPSKQWQALLQSLAH
                     DLEQGIAFSNALLPWSEVFPPLYQAMIRTGELTGKLDECCFELARQQKAQRQLTDKVK
                     SALRYPIIILAMAIMVVVAMLHFVLPEFAAIYKTFNTPLPALTQGIMTLADFSGEWSW
                     LLVLFGFLLAIANKLLMRRPTWLIVRQKLLLRIPIMGSLMRGQKLTQIFTILALTQSA
                     GITFLQGVESVRETMRCPYWVQLLTQIQHDISNGQPIWLALKNTGEFSPLCLQLVRTG
                     EASGSLDLMLDNLAHHHRENTMALADNLAALLEPALLIITGGIIGTLVVAMYLPIFHL
                     GDAMSGMG"
     misc_feature    complement(114534..115724)
                     /gene="hofC"
                     /locus_tag="b0106"
                     /gene_synonym="ECK0105; hopC; JW0102; yacD"
                     /note="type IV pilin biogenesis protein; Provisional;
                     Region: PRK10573"
                     /db_xref="CDD:182559"
     misc_feature    complement(115167..115535)
                     /gene="hofC"
                     /locus_tag="b0106"
                     /gene_synonym="ECK0105; hopC; JW0102; yacD"
                     /note="Type II secretion system (T2SS), protein F; Region:
                     T2SF; pfam00482"
                     /db_xref="CDD:249893"
     misc_feature    complement(114561..114929)
                     /gene="hofC"
                     /locus_tag="b0106"
                     /gene_synonym="ECK0105; hopC; JW0102; yacD"
                     /note="Type II secretion system (T2SS), protein F; Region:
                     T2SF; pfam00482"
                     /db_xref="CDD:249893"
     gene            complement(115714..117099)
                     /gene="hofB"
                     /locus_tag="b0107"
                     /gene_synonym="ECK0106; hopB; JW0103"
                     /db_xref="EcoGene:EG12106"
                     /db_xref="GeneID:947481"
     CDS             complement(115714..117099)
                     /gene="hofB"
                     /locus_tag="b0107"
                     /gene_synonym="ECK0106; hopB; JW0103"
                     /function="putative transport; Not classified"
                     /GO_component="GO:0009289 - pilus"
                     /note="putative integral membrane protein involved in
                     biogenesis of fimbriae, protein transport, DNA uptake"
                     /codon_start=1
                     /transl_table=11
                     /product="T2SE secretion family protein; P-loop ATPase
                     superfamily protein"
                     /protein_id="NP_414649.1"
                     /db_xref="GI:16128100"
                     /db_xref="ASAP:ABE-0000370"
                     /db_xref="UniProtKB/Swiss-Prot:P36645"
                     /db_xref="EcoGene:EG12106"
                     /db_xref="GeneID:947481"
                     /translation="MNIPQLTALCLRYHGVLLDASEEVVHVAVVDAPSHELLDALHFA
                     TTKRIEITCWTRQQMEGHASRTQQTLPVAVQEKHQPKAELLTRTLQSALEQRASDIHI
                     EPADNAYRIRLRIDGVLHPLPDVSPDAGVALTARLKVLGNLDIAEHRLPQDGQFTVEL
                     AGNAVSFRIATLPCRGGEKVVLRLLQQVGQALDVNTLGMQPLQLADFAHALQQPQGLV
                     LVTGPTGSGKTVTLYSALQKLNTADINICSVEDPVEIPIAGLNQTQIHPRAGLTFQGV
                     LRALLRQDPDVIMIGEIRDGETAEIAIKAAQTGHLVLSTLHTNSTCETLVRLQQMGVA
                     RWMLSSALTLVIAQRLVRKLCPHCRRQQGEPIHIPDNVWPSPLPHWQAPGCVHCYHGF
                     YGRTALFEVLPITPVIRQLISANTDVESLETHARQAGMRTLFENGCLAVEQGLTTFEE
                     LIRVLGMPHGE"
     misc_feature    complement(115723..117099)
                     /gene="hofB"
                     /locus_tag="b0107"
                     /gene_synonym="ECK0106; hopB; JW0103"
                     /note="hypothetical protein; Provisional; Region:
                     PRK10436"
                     /db_xref="CDD:236694"
     misc_feature    complement(115915..116694)
                     /gene="hofB"
                     /locus_tag="b0107"
                     /gene_synonym="ECK0106; hopB; JW0103"
                     /note="PulE/GspE The type II secretory pathway is the main
                     terminal branch of the general secretory pathway (GSP).
                     It is responsible for the export the majority of
                     Gram-negative bacterial exoenzymes and toxins. PulE is a
                     cytoplasmic protein of the GSP, which...; Region:
                     PulE-GspE; cd01129"
                     /db_xref="CDD:238549"
     misc_feature    complement(116413..116436)
                     /gene="hofB"
                     /locus_tag="b0107"
                     /gene_synonym="ECK0106; hopB; JW0103"
                     /note="Walker A motif; other site"
                     /db_xref="CDD:238549"
     misc_feature    complement(order(116224..116229,116347..116352,
                     116356..116358,116413..116421,116431..116433))
                     /gene="hofB"
                     /locus_tag="b0107"
                     /gene_synonym="ECK0106; hopB; JW0103"
                     /note="ATP binding site [chemical binding]; other site"
                     /db_xref="CDD:238549"
     misc_feature    complement(116224..116241)
                     /gene="hofB"
                     /locus_tag="b0107"
                     /gene_synonym="ECK0106; hopB; JW0103"
                     /note="Walker B motif; other site"
                     /db_xref="CDD:238549"
     gene            complement(117109..117549)
                     /gene="ppdD"
                     /locus_tag="b0108"
                     /gene_synonym="ECK0107; JW0104"
                     /db_xref="EcoGene:EG12107"
                     /db_xref="GeneID:945817"
     CDS             complement(117109..117549)
                     /gene="ppdD"
                     /locus_tag="b0108"
                     /gene_synonym="ECK0107; JW0104"
                     /function="putative structural component; Surface
                     structures"
                     /GO_component="GO:0009289 - pilus"
                     /note="prelipin peptidase dependent protein"
                     /codon_start=1
                     /transl_table=11
                     /product="putative prepilin peptidase-dependent pilin"
                     /protein_id="NP_414650.1"
                     /db_xref="GI:16128101"
                     /db_xref="ASAP:ABE-0000372"
                     /db_xref="UniProtKB/Swiss-Prot:P36647"
                     /db_xref="EcoGene:EG12107"
                     /db_xref="GeneID:945817"
                     /translation="MDKQRGFTLIELMVVIGIIAILSAIGIPAYQNYLRKAALTDMLQ
                     TFVPYRTAVELCALEHGGLDTCDGGSNGIPSPTTTRYVSAMSVAKGVVSLTGQESLNG
                     LSVVMTPGWDNANGVTGWTRNCNIQSDSALQQACEDVFRFDDAN"
     misc_feature    complement(117112..117549)
                     /gene="ppdD"
                     /locus_tag="b0108"
                     /gene_synonym="ECK0107; JW0104"
                     /note="putative major pilin subunit; Provisional; Region:
                     PRK10574"
                     /db_xref="CDD:236718"
     misc_feature    complement(117469..117540)
                     /gene="ppdD"
                     /locus_tag="b0108"
                     /gene_synonym="ECK0107; JW0104"
                     /note="prepilin-type N-terminal cleavage/methylation
                     domain; Region: IV_pilin_GFxxxE; TIGR02532"
                     /db_xref="CDD:213719"
     misc_feature    complement(117187..117402)
                     /gene="ppdD"
                     /locus_tag="b0108"
                     /gene_synonym="ECK0107; JW0104"
                     /note="Pilin (bacterial filament); Region: Pilin;
                     pfam00114"
                     /db_xref="CDD:249599"
     gene            complement(117752..118645)
                     /gene="nadC"
                     /locus_tag="b0109"
                     /gene_synonym="ECK0108; JW0105"
                     /db_xref="EcoGene:EG11546"
                     /db_xref="GeneID:948869"
     CDS             complement(117752..118645)
                     /gene="nadC"
                     /locus_tag="b0109"
                     /gene_synonym="ECK0108; JW0105"
                     /EC_number="2.4.2.19"
                     /function="enzyme; Biosynthesis of cofactors, carriers:
                     Pyridine nucleotide"
                     /GO_process="GO:0009435 - NAD biosynthetic process"
                     /codon_start=1
                     /transl_table=11
                     /product="quinolinate phosphoribosyltransferase"
                     /protein_id="NP_414651.1"
                     /db_xref="GI:16128102"
                     /db_xref="ASAP:ABE-0000374"
                     /db_xref="UniProtKB/Swiss-Prot:P30011"
                     /db_xref="EcoGene:EG11546"
                     /db_xref="GeneID:948869"
                     /translation="MPPRRYNPDTRRDELLERINLDIPGAVAQALREDLGGTVDANND
                     ITAKLLPENSRSHATVITRENGVFCGKRWVEEVFIQLAGDDVTIIWHVDDGDVINANQ
                     SLFELEGPSRVLLTGERTALNFVQTLSGVASKVRHYVELLEGTNTQLLDTRKTLPGLR
                     SALKYAVLCGGGANHRLGLSDAFLIKENHIIASGSVRQAVEKASWLHPDAPVEVEVEN
                     LEELDEALKAGADIIMLDNFETEQMREAVKRTNGKALLEVSGNVTDKTLREFAETGVD
                     FISVGALTKHVQALDLSMRFR"
     misc_feature    complement(117755..118645)
                     /gene="nadC"
                     /locus_tag="b0109"
                     /gene_synonym="ECK0108; JW0105"
                     /note="quinolinate phosphoribosyltransferase; Validated;
                     Region: PRK09016"
                     /db_xref="CDD:181612"
     misc_feature    complement(117761..118570)
                     /gene="nadC"
                     /locus_tag="b0109"
                     /gene_synonym="ECK0108; JW0105"
                     /note="Quinolinate phosphoribosyl transferase (QAPRTase or
                     QPRTase), also called nicotinate-nucleotide
                     pyrophosphorylase, is involved in the de novo synthesis of
                     NAD in both prokaryotes and eukaryotes. It catalyses the
                     reaction of quinolinic acid (QA) with...; Region: QPRTase;
                     cd01572"
                     /db_xref="CDD:238806"
     misc_feature    complement(order(117791..117793,118037..118039,
                     118070..118072,118079..118084,118088..118090,
                     118094..118096,118106..118111,118166..118171,
                     118181..118183,118187..118189,118277..118279,
                     118289..118294,118505..118510))
                     /gene="nadC"
                     /locus_tag="b0109"
                     /gene_synonym="ECK0108; JW0105"
                     /note="dimerization interface [polypeptide binding]; other
                     site"
                     /db_xref="CDD:238806"
     misc_feature    complement(order(117791..117793,117800..117805,
                     117809..117811,117866..117871,117938..117940,
                     118118..118123,118184..118192))
                     /gene="nadC"
                     /locus_tag="b0109"
                     /gene_synonym="ECK0108; JW0105"
                     /note="active site"
                     /db_xref="CDD:238806"
     gene            118733..119284
                     /gene="ampD"
                     /locus_tag="b0110"
                     /gene_synonym="ECK0109; JW0106"
                     /db_xref="EcoGene:EG10041"
                     /db_xref="GeneID:948877"
     CDS             118733..119284
                     /gene="ampD"
                     /locus_tag="b0110"
                     /gene_synonym="ECK0109; JW0106"
                     /EC_number="3.5.1.28"
                     /function="regulator; Not classified"
                     /GO_component="GO:0009274 - peptidoglycan-based cell wall"
                     /GO_component="GO:0005737 - cytoplasm"
                     /GO_process="GO:0000270 - peptidoglycan metabolic process"
                     /note="regulates ampC"
                     /codon_start=1
                     /transl_table=11
                     /product="1,6-anhydro-N-acetylmuramyl-L-alanine amidase,
                     Zn-dependent; murein amidase"
                     /protein_id="NP_414652.1"
                     /db_xref="GI:16128103"
                     /db_xref="ASAP:ABE-0000380"
                     /db_xref="UniProtKB/Swiss-Prot:P13016"
                     /db_xref="EcoGene:EG10041"
                     /db_xref="GeneID:948877"
                     /translation="MLLEQGWLVGARRVPSPHYDCRPDDETPTLLVVHNISLPPGEFG
                     GPWIDALFTGTIDPQAHPFFAEIAHLRVSAHCLIRRDGEIVQYVPFDKRAWHAGVSQY
                     QGRERCNDFSIGIELEGTDTLAYTDAQYQQLAAVTRALIDCYPDIAKNMTGHCDIAPD
                     RKTDPGPAFDWARFRVLVSKETT"
     misc_feature    118739..>119257
                     /gene="ampD"
                     /locus_tag="b0110"
                     /gene_synonym="ECK0109; JW0106"
                     /note="N-acetyl-anhydromuramyl-L-alanine amidase [Cell
                     envelope biogenesis, outer membrane]; Region: ampD;
                     COG3023"
                     /db_xref="CDD:225567"
     misc_feature    118814..119236
                     /gene="ampD"
                     /locus_tag="b0110"
                     /gene_synonym="ECK0109; JW0106"
                     /note="Peptidoglycan recognition proteins (PGRPs) are
                     pattern recognition receptors that bind, and in certain
                     cases, hydrolyze peptidoglycans (PGNs) of bacterial cell
                     walls. PGRPs have been divided into three classes: short
                     PGRPs (PGRP-S), that are small (20...; Region: PGRP;
                     cd06583"
                     /db_xref="CDD:133475"
     misc_feature    order(118832..118834,118952..118954,119192..119194,
                     119216..119218,119222..119224)
                     /gene="ampD"
                     /locus_tag="b0110"
                     /gene_synonym="ECK0109; JW0106"
                     /note="amidase catalytic site [active]"
                     /db_xref="CDD:133475"
     misc_feature    order(118832..118834,119192..119194,119222..119224)
                     /gene="ampD"
                     /locus_tag="b0110"
                     /gene_synonym="ECK0109; JW0106"
                     /note="Zn binding residues [ion binding]; other site"
                     /db_xref="CDD:133475"
     misc_feature    order(118835..118840,118910..118912,118952..118954,
                     118994..118996,119015..119020,119057..119059,
                     119192..119194,119204..119206,119216..119224)
                     /gene="ampD"
                     /locus_tag="b0110"
                     /gene_synonym="ECK0109; JW0106"
                     /note="substrate binding site [chemical binding]; other
                     site"
                     /db_xref="CDD:133475"
     gene            119281..120135
                     /gene="ampE"
                     /locus_tag="b0111"
                     /gene_synonym="ECK0110; JW0107"
                     /db_xref="EcoGene:EG10042"
                     /db_xref="GeneID:946678"
     CDS             119281..120135
                     /gene="ampE"
                     /locus_tag="b0111"
                     /gene_synonym="ECK0110; JW0107"
                     /function="regulator; Drug/analog sensitivity"
                     /GO_component="GO:0009274 - peptidoglycan-based cell wall"
                     /GO_component="GO:0019866 - organelle inner membrane"
                     /GO_process="GO:0042493 - response to drug"
                     /note="regulates ampC"
                     /codon_start=1
                     /transl_table=11
                     /product="ampicillin resistance inner membrane protein;
                     putative signaling protein in beta-lactamase regulation"
                     /protein_id="NP_414653.1"
                     /db_xref="GI:16128104"
                     /db_xref="ASAP:ABE-0000382"
                     /db_xref="UniProtKB/Swiss-Prot:P0AE14"
                     /db_xref="EcoGene:EG10042"
                     /db_xref="GeneID:946678"
                     /translation="MTLFTTLLVLIFERLFKLGEHWQLDHRLEAFFRRVKHFSLGRTL
                     GMTIIAMGVTFLLLRALQGVLFNVPTLLVWLLIGLLCIGAGKVRLHYHAYLTAASRND
                     SHARATMAGELTMIHGVPAGCDEREYLRELQNALLWINFRFYLAPLFWLIVGGTWGPV
                     TLMGYAFLRAWQYWLARYQTPHHRLQSGIDAVLHVLDWVPVRLAGVVYALIGHGEKAL
                     PAWFASLGDFHTSQYQVLTRLAQFSLAREPHVDKVETPKAAVSMAKKTSFVVVVVIAL
                     LTIYGALV"
     misc_feature    119281..120132
                     /gene="ampE"
                     /locus_tag="b0111"
                     /gene_synonym="ECK0110; JW0107"
                     /note="regulatory protein AmpE; Provisional; Region:
                     PRK10987"
                     /db_xref="CDD:236811"
     gene            complement(120178..121551)
                     /gene="aroP"
                     /locus_tag="b0112"
                     /gene_synonym="ECK0111; JW0108"
                     /db_xref="EcoGene:EG10084"
                     /db_xref="GeneID:946018"
     CDS             complement(120178..121551)
                     /gene="aroP"
                     /locus_tag="b0112"
                     /gene_synonym="ECK0111; JW0108"
                     /function="transport; Transport of small molecules: Amino
                     acids, amines"
                     /GO_component="GO:0009274 - peptidoglycan-based cell wall"
                     /GO_component="GO:0019866 - organelle inner membrane"
                     /GO_process="GO:0009094 - L-phenylalanine biosynthetic
                     process"
                     /GO_process="GO:0006571 - tyrosine biosynthetic process"
                     /note="aromatic amino acid transport protein"
                     /codon_start=1
                     /transl_table=11
                     /product="aromatic amino acid transporter"
                     /protein_id="NP_414654.1"
                     /db_xref="GI:16128105"
                     /db_xref="ASAP:ABE-0000384"
                     /db_xref="UniProtKB/Swiss-Prot:P15993"
                     /db_xref="EcoGene:EG10084"
                     /db_xref="GeneID:946018"
                     /translation="MMEGQQHGEQLKRGLKNRHIQLIALGGAIGTGLFLGSASVIQSA
                     GPGIILGYAIAGFIAFLIMRQLGEMVVEEPVAGSFSHFAYKYWGSFAGFASGWNYWVL
                     YVLVAMAELTAVGKYIQFWYPEIPTWVSAAVFFVVINAINLTNVKVFGEMEFWFAIIK
                     VIAVVAMIIFGGWLLFSGNGGPQATVSNLWDQGGFLPHGFTGLVMMMAIIMFSFGGLE
                     LVGITAAEADNPEQSIPKATNQVIYRILIFYIGSLAVLLSLMPWTRVTADTSPFVLIF
                     HELGDTFVANALNIVVLTAALSVYNSCVYCNSRMLFGLAQQGNAPKALASVDKRGVPV
                     NTILVSALVTALCVLINYLAPESAFGLLMALVVSALVINWAMISLAHMKFRRAKQEQG
                     VVTRFPALLYPLGNWICLLFMAAVLVIMLMTPGMAISVYLIPVWLIVLGIGYLFKEKT
                     AKAVKAH"
     misc_feature    complement(120181..121548)
                     /gene="aroP"
                     /locus_tag="b0112"
                     /gene_synonym="ECK0111; JW0108"
                     /note="aromatic amino acid transporter; Provisional;
                     Region: PRK10238"
                     /db_xref="CDD:182324"
     misc_feature    complement(120214..121431)
                     /gene="aroP"
                     /locus_tag="b0112"
                     /gene_synonym="ECK0111; JW0108"
                     /note="Transmembrane amino acid transporter protein;
                     Region: Aa_trans; cl17468"
                     /db_xref="CDD:266708"
     gene            122092..122856
                     /gene="pdhR"
                     /locus_tag="b0113"
                     /gene_synonym="aceC; ECK0112; genA; JW0109; yacB"
                     /db_xref="EcoGene:EG11088"
                     /db_xref="GeneID:944827"
     CDS             122092..122856
                     /gene="pdhR"
                     /locus_tag="b0113"
                     /gene_synonym="aceC; ECK0112; genA; JW0109; yacB"
                     /function="regulator; Energy metabolism, carbon: Pyruvate
                     dehydrogenase"
                     /GO_component="GO:0005737 - cytoplasm"
                     /GO_function="GO:0016564 - transcription repressor
                     activity"
                     /GO_process="GO:0006096 - glycolysis"
                     /GO_process="GO:0006350 - transcription"
                     /note="transcriptional regulator for pyruvate
                     dehydrogenase complex"
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate dehydrogenase complex repressor;
                     autorepressor"
                     /protein_id="NP_414655.1"
                     /db_xref="GI:16128106"
                     /db_xref="ASAP:ABE-0000394"
                     /db_xref="UniProtKB/Swiss-Prot:P0ACL9"
                     /db_xref="EcoGene:EG11088"
                     /db_xref="GeneID:944827"
                     /translation="MAYSKIRQPKLSDVIEQQLEFLILEGTLRPGEKLPPERELAKQF
                     DVSRPSLREAIQRLEAKGLLLRRQGGGTFVQSSLWQSFSDPLVELLSDHPESQYDLLE
                     TRHALEGIAAYYAALRSTDEDKERIRELHHAIELAQQSGDLDAESNAVLQYQIAVTEA
                     AHNVVLLHLLRCMEPMLAQNVRQNFELLYSRREMLPLVSSHRTRIFEAIMAGKPEEAR
                     EASHRHLAFIEEILLDRSREESRRERSLRRLEQRKN"
     misc_feature    122092..122793
                     /gene="pdhR"
                     /locus_tag="b0113"
                     /gene_synonym="aceC; ECK0112; genA; JW0109; yacB"
                     /note="transcriptional regulator PdhR; Reviewed; Region:
                     pdhR; PRK09464"
                     /db_xref="CDD:181879"
     misc_feature    122119..122313
                     /gene="pdhR"
                     /locus_tag="b0113"
                     /gene_synonym="aceC; ECK0112; genA; JW0109; yacB"
                     /note="Winged helix-turn-helix (WHTH) DNA-binding domain
                     of the GntR family of transcriptional regulators; Region:
                     WHTH_GntR; cd07377"
                     /db_xref="CDD:153418"
     misc_feature    order(122119..122121,122125..122127,122194..122196,
                     122200..122205,122227..122241,122245..122250,
                     122257..122259,122287..122292,122296..122307)
                     /gene="pdhR"
                     /locus_tag="b0113"
                     /gene_synonym="aceC; ECK0112; genA; JW0109; yacB"
                     /note="DNA-binding site [nucleotide binding]; DNA binding
                     site"
                     /db_xref="CDD:153418"
     misc_feature    122386..122769
                     /gene="pdhR"
                     /locus_tag="b0113"
                     /gene_synonym="aceC; ECK0112; genA; JW0109; yacB"
                     /note="This entry represents the C-terminal ligand binding
                     domain of many members of the GntR family; Region: FCD;
                     smart00895"
                     /db_xref="CDD:214892"
     gene            123017..125680
                     /gene="aceE"
                     /locus_tag="b0114"
                     /gene_synonym="ECK0113; JW0110"
                     /db_xref="EcoGene:EG10024"
                     /db_xref="GeneID:944834"
     CDS             123017..125680
                     /gene="aceE"
                     /locus_tag="b0114"
                     /gene_synonym="ECK0113; JW0110"
                     /EC_number="1.2.4.1"
                     /function="enzyme; Energy metabolism, carbon: Pyruvate
                     dehydrogenase"
                     /GO_process="GO:0016052 - carbohydrate catabolic process"
                     /GO_process="GO:0006086 - acetyl-CoA biosynthetic process
                     from pyruvate"
                     /GO_process="GO:0006096 - glycolysis"
                     /GO_process="GO:0009436 - glyoxylate catabolic process"
                     /GO_process="GO:0009061 - anaerobic respiration"
                     /note="pyruvate dehydrogenase (decarboxylase component)"
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate dehydrogenase, decarboxylase component
                     E1, thiamine triphosphate-binding"
                     /protein_id="NP_414656.1"
                     /db_xref="GI:16128107"
                     /db_xref="ASAP:ABE-0000397"
                     /db_xref="UniProtKB/Swiss-Prot:P0AFG8"
                     /db_xref="EcoGene:EG10024"
                     /db_xref="GeneID:944834"
                     /translation="MSERFPNDVDPIETRDWLQAIESVIREEGVERAQYLIDQLLAEA
                     RKGGVNVAAGTGISNYINTIPVEEQPEYPGNLELERRIRSAIRWNAIMTVLRASKKDL
                     ELGGHMASFQSSATIYDVCFNHFFRARNEQDGGDLVYFQGHISPGVYARAFLEGRLTQ
                     EQLDNFRQEVHGNGLSSYPHPKLMPEFWQFPTVSMGLGPIGAIYQAKFLKYLEHRGLK
                     DTSKQTVYAFLGDGEMDEPESKGAITIATREKLDNLVFVINCNLQRLDGPVTGNGKII
                     NELEGIFEGAGWNVIKVMWGSRWDELLRKDTSGKLIQLMNETVDGDYQTFKSKDGAYV
                     REHFFGKYPETAALVADWTDEQIWALNRGGHDPKKIYAAFKKAQETKGKATVILAHTI
                     KGYGMGDAAEGKNIAHQVKKMNMDGVRHIRDRFNVPVSDADIEKLPYITFPEGSEEHT
                     YLHAQRQKLHGYLPSRQPNFTEKLELPSLQDFGALLEEQSKEISTTIAFVRALNVMLK
                     NKSIKDRLVPIIADEARTFGMEGLFRQIGIYSPNGQQYTPQDREQVAYYKEDEKGQIL
                     QEGINELGAGCSWLAAATSYSTNNLPMIPFYIYYSMFGFQRIGDLCWAAGDQQARGFL
                     IGGTSGRTTLNGEGLQHEDGHSHIQSLTIPNCISYDPAYAYEVAVIMHDGLERMYGEK
                     QENVYYYITTLNENYHMPAMPEGAEEGIRKGIYKLETIEGSKGKVQLLGSGSILRHVR
                     EAAEILAKDYGVGSDVYSVTSFTELARDGQDCERWNMLHPLETPRVPYIAQVMNDAPA
                     VASTDYMKLFAEQVRTYVPADDYRVLGTDGFGRSDSRENLRHHFEVDASYVVVAALGE
                     LAKRGEIDKKVVADAIAKFNIDADKVNPRLA"
     misc_feature    123017..125677
                     /gene="aceE"
                     /locus_tag="b0114"
                     /gene_synonym="ECK0113; JW0110"
                     /note="pyruvate dehydrogenase subunit E1; Reviewed;
                     Region: aceE; PRK09405"
                     /db_xref="CDD:236500"
     misc_feature    123242..124399
                     /gene="aceE"
                     /locus_tag="b0114"
                     /gene_synonym="ECK0113; JW0110"
                     /note="Thiamine pyrophosphate (TPP) family, E1 of E. coli
                     PDC-like subfamily, TPP-binding module; composed of
                     proteins similar to the E1 component of the Escherichia
                     coli pyruvate dehydrogenase multienzyme complex (PDC). PDC
                     catalyzes the oxidative...; Region: TPP_E1_EcPDC_like;
                     cd02017"
                     /db_xref="CDD:238975"
     misc_feature    order(123320..123328,123515..123526,123545..123550,
                     123554..123556,123560..123562,123587..123589,
                     123593..123601,123719..123730,123737..123739,
                     123746..123748,123758..123760,123806..123814,
                     123824..123826,123848..123850,123857..123862,
                     123869..123871)
                     /gene="aceE"
                     /locus_tag="b0114"
                     /gene_synonym="ECK0113; JW0110"
                     /note="dimer interface [polypeptide binding]; other site"
                     /db_xref="CDD:238975"
     misc_feature    order(123344..123346,123437..123439,123443..123445,
                     123593..123595,123599..123601,123707..123715,
                     123722..123724,123797..123799,123803..123805,
                     124193..124195)
                     /gene="aceE"
                     /locus_tag="b0114"
                     /gene_synonym="ECK0113; JW0110"
                     /note="TPP-binding site [chemical binding]; other site"
                     /db_xref="CDD:238975"
     gene            125695..127587
                     /gene="aceF"
                     /locus_tag="b0115"
                     /gene_synonym="ECK0114; JW0111"
                     /db_xref="EcoGene:EG10025"
                     /db_xref="GeneID:944794"
     CDS             125695..127587
                     /gene="aceF"
                     /locus_tag="b0115"
                     /gene_synonym="ECK0114; JW0111"
                     /EC_number="2.3.1.12"
                     /function="enzyme; Energy metabolism, carbon: Pyruvate
                     dehydrogenase"
                     /GO_process="GO:0016052 - carbohydrate catabolic process"
                     /GO_process="GO:0006086 - acetyl-CoA biosynthetic process
                     from pyruvate"
                     /GO_process="GO:0006096 - glycolysis"
                     /GO_process="GO:0009436 - glyoxylate catabolic process"
                     /GO_process="GO:0009061 - anaerobic respiration"
                     /note="pyruvate dehydrogenase (dihydrolipoyltransacetylase
                     component)"
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate dehydrogenase,
                     dihydrolipoyltransacetylase component E2"
                     /protein_id="NP_414657.1"
                     /db_xref="GI:16128108"
                     /db_xref="ASAP:ABE-0000400"
                     /db_xref="UniProtKB/Swiss-Prot:P06959"
                     /db_xref="EcoGene:EG10025"
                     /db_xref="GeneID:944794"
                     /translation="MAIEIKVPDIGADEVEITEILVKVGDKVEAEQSLITVEGDKASM
                     EVPSPQAGIVKEIKVSVGDKTQTGALIMIFDSADGAADAAPAQAEEKKEAAPAAAPAA
                     AAAKDVNVPDIGSDEVEVTEILVKVGDKVEAEQSLITVEGDKASMEVPAPFAGTVKEI
                     KVNVGDKVSTGSLIMVFEVAGEAGAAAPAAKQEAAPAAAPAPAAGVKEVNVPDIGGDE
                     VEVTEVMVKVGDKVAAEQSLITVEGDKASMEVPAPFAGVVKELKVNVGDKVKTGSLIM
                     IFEVEGAAPAAAPAKQEAAAPAPAAKAEAPAAAPAAKAEGKSEFAENDAYVHATPLIR
                     RLAREFGVNLAKVKGTGRKGRILREDVQAYVKEAIKRAEAAPAATGGGIPGMLPWPKV
                     DFSKFGEIEEVELGRIQKISGANLSRNWVMIPHVTHFDKTDITELEAFRKQQNEEAAK
                     RKLDVKITPVVFIMKAVAAALEQMPRFNSSLSEDGQRLTLKKYINIGVAVDTPNGLVV
                     PVFKDVNKKGIIELSRELMTISKKARDGKLTAGEMQGGCFTISSIGGLGTTHFAPIVN
                     APEVAILGVSKSAMEPVWNGKEFVPRLMLPISLSFDHRVIDGADGARFITIINNTLSD
                     IRRLVM"
     misc_feature    125695..127584
                     /gene="aceF"
                     /locus_tag="b0115"
                     /gene_synonym="ECK0114; JW0111"
                     /note="pyruvate dehydrogenase dihydrolipoyltransacetylase;
                     Validated; Region: aceF; PRK11854"
                     /db_xref="CDD:236999"
     misc_feature    125701..125916
                     /gene="aceF"
                     /locus_tag="b0115"
                     /gene_synonym="ECK0114; JW0111"
                     /note="Lipoyl domain of the dihydrolipoyl acyltransferase
                     component (E2) of 2-oxo acid dehydrogenases. 2-oxo acid
                     dehydrogenase multienzyme complexes, like pyruvate
                     dehydrogenase (PDH), 2-oxoglutarate dehydrogenase (OGDH)
                     and branched-chain 2-oxo acid...; Region: lipoyl_domain;
                     cd06849"
                     /db_xref="CDD:133458"
     misc_feature    order(125785..125787,125806..125823,125833..125835)
                     /gene="aceF"
                     /locus_tag="b0115"
                     /gene_synonym="ECK0114; JW0111"
                     /note="E3 interaction surface; other site"
                     /db_xref="CDD:133458"
     misc_feature    125815..125817
                     /gene="aceF"
                     /locus_tag="b0115"
                     /gene_synonym="ECK0114; JW0111"
                     /note="lipoyl attachment site [posttranslational
                     modification]; other site"
                     /db_xref="CDD:133458"
     misc_feature    126013..126225
                     /gene="aceF"
                     /locus_tag="b0115"
                     /gene_synonym="ECK0114; JW0111"
                     /note="Lipoyl domain of the dihydrolipoyl acyltransferase
                     component (E2) of 2-oxo acid dehydrogenases. 2-oxo acid
                     dehydrogenase multienzyme complexes, like pyruvate
                     dehydrogenase (PDH), 2-oxoglutarate dehydrogenase (OGDH)
                     and branched-chain 2-oxo acid...; Region: lipoyl_domain;
                     cd06849"
                     /db_xref="CDD:133458"
     misc_feature    order(126094..126096,126115..126132,126142..126144)
                     /gene="aceF"
                     /locus_tag="b0115"
                     /gene_synonym="ECK0114; JW0111"
                     /note="E3 interaction surface; other site"
                     /db_xref="CDD:133458"
     misc_feature    126124..126126
                     /gene="aceF"
                     /locus_tag="b0115"
                     /gene_synonym="ECK0114; JW0111"
                     /note="lipoyl attachment site [posttranslational
                     modification]; other site"
                     /db_xref="CDD:133458"
     misc_feature    126313..126528
                     /gene="aceF"
                     /locus_tag="b0115"
                     /gene_synonym="ECK0114; JW0111"
                     /note="Lipoyl domain of the dihydrolipoyl acyltransferase
                     component (E2) of 2-oxo acid dehydrogenases. 2-oxo acid
                     dehydrogenase multienzyme complexes, like pyruvate
                     dehydrogenase (PDH), 2-oxoglutarate dehydrogenase (OGDH)
                     and branched-chain 2-oxo acid...; Region: lipoyl_domain;
                     cd06849"
                     /db_xref="CDD:133458"
     misc_feature    order(126397..126399,126418..126435,126445..126447)
                     /gene="aceF"
                     /locus_tag="b0115"
                     /gene_synonym="ECK0114; JW0111"
                     /note="E3 interaction surface; other site"
                     /db_xref="CDD:133458"
     misc_feature    126427..126429
                     /gene="aceF"
                     /locus_tag="b0115"
                     /gene_synonym="ECK0114; JW0111"
                     /note="lipoyl attachment site [posttranslational
                     modification]; other site"
                     /db_xref="CDD:133458"
     misc_feature    126673..126783
                     /gene="aceF"
                     /locus_tag="b0115"
                     /gene_synonym="ECK0114; JW0111"
                     /note="e3 binding domain; Region: E3_binding; pfam02817"
                     /db_xref="CDD:251550"
     misc_feature    126940..127584
                     /gene="aceF"
                     /locus_tag="b0115"
                     /gene_synonym="ECK0114; JW0111"
                     /note="2-oxoacid dehydrogenases acyltransferase (catalytic
                     domain); Region: 2-oxoacid_dh; pfam00198"
                     /db_xref="CDD:249671"
     gene            127912..129336
                     /gene="lpd"
                     /locus_tag="b0116"
                     /gene_synonym="dhl; ECK0115; JW0112; lpdA"
                     /db_xref="EcoGene:EG10543"
                     /db_xref="GeneID:944854"
     CDS             127912..129336
                     /gene="lpd"
                     /locus_tag="b0116"
                     /gene_synonym="dhl; ECK0115; JW0112; lpdA"
                     /EC_number="1.8.1.4"
                     /function="enzyme; Energy metabolism, carbon: Pyruvate
                     dehydrogenase"
                     /GO_component="GO:0005737 - cytoplasm"
                     /GO_process="GO:0016052 - carbohydrate catabolic process"
                     /GO_process="GO:0009063 - cellular amino acid catabolic
                     process"
                     /GO_process="GO:0006096 - glycolysis"
                     /GO_process="GO:0006086 - acetyl-CoA biosynthetic process
                     from pyruvate"
                     /GO_process="GO:0006099 - tricarboxylic acid cycle"
                     /GO_process="GO:0009060 - aerobic respiration"
                     /GO_process="GO:0009061 - anaerobic respiration"
                     /GO_process="GO:0009436 - glyoxylate catabolic process"
                     /note="lipoamide dehydrogenase (NADH); component of
                     2-oxodehydrogenase and pyruvate complexes; L-protein of
                     glycine cleavage complex"
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrolipoyl dehydrogenase; E3 component of
                     pyruvate and 2-oxoglutarate dehydrogenases complexes;
                     glycine cleavage system L protein; dihydrolipoamide
                     dehydrogenase"
                     /protein_id="NP_414658.1"
                     /db_xref="GI:16128109"
                     /db_xref="ASAP:ABE-0000404"
                     /db_xref="UniProtKB/Swiss-Prot:P0A9P0"
                     /db_xref="EcoGene:EG10543"
                     /db_xref="GeneID:944854"
                     /translation="MSTEIKTQVVVLGAGPAGYSAAFRCADLGLETVIVERYNTLGGV
                     CLNVGCIPSKALLHVAKVIEEAKALAEHGIVFGEPKTDIDKIRTWKEKVINQLTGGLA
                     GMAKGRKVKVVNGLGKFTGANTLEVEGENGKTVINFDNAIIAAGSRPIQLPFIPHEDP
                     RIWDSTDALELKEVPERLLVMGGGIIGLEMGTVYHALGSQIDVVEMFDQVIPAADKDI
                     VKVFTKRISKKFNLMLETKVTAVEAKEDGIYVTMEGKKAPAEPQRYDAVLVAIGRVPN
                     GKNLDAGKAGVEVDDRGFIRVDKQLRTNVPHIFAIGDIVGQPMLAHKGVHEGHVAAEV
                     IAGKKHYFDPKVIPSIAYTEPEVAWVGLTEKEAKEKGISYETATFPWAASGRAIASDC
                     ADGMTKLIFDKESHRVIGGAIVGTNGGELLGEIGLAIEMGCDAEDIALTIHAHPTLHE
                     SVGLAAEVFEGSITDLPNPKAKKK"
     misc_feature    127918..129327
                     /gene="lpd"
                     /locus_tag="b0116"
                     /gene_synonym="dhl; ECK0115; JW0112; lpdA"
                     /note="dihydrolipoamide dehydrogenase; Reviewed; Region:
                     PRK06467"
                     /db_xref="CDD:180579"
     misc_feature    127936..>128040
                     /gene="lpd"
                     /locus_tag="b0116"
                     /gene_synonym="dhl; ECK0115; JW0112; lpdA"
                     /note="NAD(P)-binding Rossmann-like domain; Region:
                     NAD_binding_8; cl19134"
                     /db_xref="CDD:267487"
     misc_feature    128440..128676
                     /gene="lpd"
                     /locus_tag="b0116"
                     /gene_synonym="dhl; ECK0115; JW0112; lpdA"
                     /note="Pyridine nucleotide-disulphide oxidoreductase;
                     Region: Pyr_redox; pfam00070"
                     /db_xref="CDD:249559"
     misc_feature    128950..129279
                     /gene="lpd"
                     /locus_tag="b0116"
                     /gene_synonym="dhl; ECK0115; JW0112; lpdA"
                     /note="Pyridine nucleotide-disulphide oxidoreductase,
                     dimerization domain; Region: Pyr_redox_dim; pfam02852"
                     /db_xref="CDD:251571"
     repeat_region   129347..129361
                     /note="REP9 (repetitive extragenic palindromic) element;
                     contains 1 REP sequences"
     gene            complement(129407..131260)
                     /gene="yacH"
                     /locus_tag="b0117"
                     /gene_synonym="ECK0116; JW0113"
                     /db_xref="EcoGene:EG12315"
                     /db_xref="GeneID:944868"
     CDS             complement(129407..131260)
                     /gene="yacH"
                     /locus_tag="b0117"
                     /gene_synonym="ECK0116; JW0113"
                     /function="putative membrane; Not classified"
                     /GO_component="GO:0009274 - peptidoglycan-based cell wall"
                     /note="putative membrane protein"
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3300 family protein"
                     /protein_id="NP_414659.1"
                     /db_xref="GI:16128110"
                     /db_xref="ASAP:ABE-0000406"
                     /db_xref="UniProtKB/Swiss-Prot:P36682"
                     /db_xref="EcoGene:EG12315"
                     /db_xref="GeneID:944868"
                     /translation="MKMTLPFKPHVLALICSAGLCAASTGLYIKSRTVEAPVEPQSTQ
                     LAVSDAAAVTFPATVSAPPVTPAVVKSAFSTAQIDQWVAPVALYPDALLSQVLMASTY
                     PTNVAQAVQWSHDNPLKQGDAAIQAVSDQPWDASVKSLVAFPQLMALMGENPQWVQNL
                     GDAFLAQPQDVMDSVQRLRQLAQQTGSLKSSTEQKVITTTKKAVPVKQTVTAPVIPSN
                     TVLTANPVITEPATTVISIEPANPDVVYIPNYNPTVVYGNWANTAYPPVYLPPPAGEP
                     FVDSFVRGFGYSMGVATTYALFSSIDWDDDDHDHHHHDNDDYHHHDGGHRDGNGWQHN
                     GDNINIDVNNFNRITGEHLTDKNMAWRHNPNYRNGVPYHDQDMAKRFHQTDVNGGMSA
                     TQLPAPTRDSQRQAAANQFQQRTHAAPVITRDTQRQAAAQRFNEAEHYGSYDDFHDFS
                     RRQPLTQQQKDAARQRYQSASPEQRQAVRERMQTNPKIQQRREAARERIQSASPEQRQ
                     AVREKMQTNPQNQQRRDAARERIQSASPEQRQVFKEKVQQRPLNQQQRDNARQRVQSA
                     SPEQRQVFREKVQESRPQRLNDSNHTVRLNNEQRSAVCERLSERGARRLER"
     misc_feature    complement(130172..131044)
                     /gene="yacH"
                     /locus_tag="b0117"
                     /gene_synonym="ECK0116; JW0113"
                     /note="Protein of unknown function (DUF3300); Region:
                     DUF3300; pfam11737"
                     /db_xref="CDD:256584"
     misc_feature    complement(129530..129865)
                     /gene="yacH"
                     /locus_tag="b0117"
                     /gene_synonym="ECK0116; JW0113"
                     /note="Protein of unknown function (DUF3106); Region:
                     DUF3106; pfam11304"
                     /db_xref="CDD:256404"
     gene            131615..134212
                     /gene="acnB"
                     /locus_tag="b0118"
                     /gene_synonym="ECK0117; JW0114; yacI; yacJ"
                     /db_xref="EcoGene:EG12316"
                     /db_xref="GeneID:944864"
     CDS             131615..134212
                     /gene="acnB"
                     /locus_tag="b0118"
                     /gene_synonym="ECK0117; JW0114; yacI; yacJ"
                     /EC_number="4.2.1.3"
                     /EC_number="4.2.1.99"
                     /function="enzyme; Energy metabolism, carbon: TCA cycle"
                     /experiment="N-terminus verified by Edman degradation:
                     PMID 8932712,9298646,12473114"
                     /GO_process="GO:0006099 - tricarboxylic acid cycle"
                     /GO_process="GO:0009060 - aerobic respiration"
                     /GO_process="GO:0009061 - anaerobic respiration"
                     /note="aconitate hydrase B"
                     /codon_start=1
                     /transl_table=11
                     /product="aconitate hydratase 2; aconitase B;
                     2-methyl-cis-aconitate hydratase"
                     /protein_id="NP_414660.1"
                     /db_xref="GI:16128111"
                     /db_xref="ASAP:ABE-0000411"
                     /db_xref="UniProtKB/Swiss-Prot:P36683"
                     /db_xref="EcoGene:EG12316"
                     /db_xref="GeneID:944864"
                     /translation="MLEEYRKHVAERAAEGIAPKPLDANQMAALVELLKNPPAGEEEF
                     LLDLLTNRVPPGVDEAAYVKAGFLAAIAKGEAKSPLLTPEKAIELLGTMQGGYNIHPL
                     IDALDDAKLAPIAAKALSHTLLMFDNFYDVEEKAKAGNEYAKQVMQSWADAEWFLNRP
                     ALAEKLTVTVFKVTGETNTDDLSPAPDAWSRPDIPLHALAMLKNAREGIEPDQPGVVG
                     PIKQIEALQQKGFPLAYVGDVVGTGSSRKSATNSVLWFMGDDIPHVPNKRGGGLCLGG
                     KIAPIFFNTMEDAGALPIEVDVSNLNMGDVIDVYPYKGEVRNHETGELLATFELKTDV
                     LIDEVRAGGRIPLIIGRGLTTKAREALGLPHSDVFRQAKDVAESDRGFSLAQKMVGRA
                     CGVKGIRPGAYCEPKMTSVGSQDTTGPMTRDELKDLACLGFSADLVMQSFCHTAAYPK
                     PVDVNTHHTLPDFIMNRGGVSLRPGDGVIHSWLNRMLLPDTVGTGGDSHTRFPIGISF
                     PAGSGLVAFAAATGVMPLDMPESVLVRFKGKMQPGITLRDLVHAIPLYAIKQGLLTVE
                     KKGKKNIFSGRILEIEGLPDLKVEQAFELTDASAERSAAGCTIKLNKEPIIEYLNSNI
                     VLLKWMIAEGYGDRRTLERRIQGMEKWLANPELLEADADAEYAAVIDIDLADIKEPIL
                     CAPNDPDDARPLSAVQGEKIDEVFIGSCMTNIGHFRAAGKLLDAHKGQLPTRLWVAPP
                     TRMDAAQLTEEGYYSVFGKSGARIEIPGCSLCMGNQARVADGATVVSTSTRNFPNRLG
                     TGANVFLASAELAAVAALIGKLPTPEEYQTYVAQVDKTAVDTYRYLNFNQLSQYTEKA
                     DGVIFQTAV"
     misc_feature    131615..134152
                     /gene="acnB"
                     /locus_tag="b0118"
                     /gene_synonym="ECK0117; JW0114; yacI; yacJ"
                     /note="bifunctional aconitate hydratase
                     2/2-methylisocitrate dehydratase; Validated; Region:
                     PRK09238"
                     /db_xref="CDD:236424"
     misc_feature    131624..132082
                     /gene="acnB"
                     /locus_tag="b0118"
                     /gene_synonym="ECK0117; JW0114; yacI; yacJ"
                     /note="Aconitate B N-terminal domain; Region:
                     Aconitase_B_N; pfam11791"
                     /db_xref="CDD:256624"
     misc_feature    132125..132547
                     /gene="acnB"
                     /locus_tag="b0118"
                     /gene_synonym="ECK0117; JW0114; yacI; yacJ"
                     /note="Aconitase B swivel domain. Aconitate hydratase B is
                     involved in energy metabolism as part of the TCA cycle. It
                     catalyses the formation of cis-aconitate from citrate.
                     This is the aconitase swivel domain, which undergoes
                     swivelling conformational change in...; Region:
                     AcnB_Swivel; cd01576"
                     /db_xref="CDD:238808"
     misc_feature    132344..132352
                     /gene="acnB"
                     /locus_tag="b0118"
                     /gene_synonym="ECK0117; JW0114; yacI; yacJ"
                     /note="substrate binding site [chemical binding]; other
                     site"
                     /db_xref="CDD:238808"
     misc_feature    132764..134074
                     /gene="acnB"
                     /locus_tag="b0118"
                     /gene_synonym="ECK0117; JW0114; yacI; yacJ"
                     /note="Aconitate hydratase B catalyses the formation of
                     cis-aconitate from citrate as part of the TCA cycle;
                     Region: AcnB; cd01581"
                     /db_xref="CDD:153131"
     misc_feature    order(132854..132856,132863..132865,133103..133108,
                     133931..133933,133985..133987,134000..134002)
                     /gene="acnB"
                     /locus_tag="b0118"
                     /gene_synonym="ECK0117; JW0114; yacI; yacJ"
                     /note="substrate binding site [chemical binding]; other
                     site"
                     /db_xref="CDD:153131"
     misc_feature    order(133109..133111,133742..133744,133919..133921,
                     133928..133933,133982..133984)
                     /gene="acnB"
                     /locus_tag="b0118"
                     /gene_synonym="ECK0117; JW0114; yacI; yacJ"
                     /note="ligand binding site [chemical binding]; other site"
                     /db_xref="CDD:153131"
     gene            134388..134750
                     /gene="yacL"
                     /locus_tag="b0119"
                     /gene_synonym="ECK0118; JW0115"
                     /db_xref="EcoGene:EG12605"
                     /db_xref="GeneID:944809"
     CDS             134388..134750
                     /gene="yacL"
                     /locus_tag="b0119"
                     /gene_synonym="ECK0118; JW0115"
                     /codon_start=1
                     /transl_table=11
                     /product="UPF0231 family protein"
                     /protein_id="NP_414661.2"
                     /db_xref="GI:90111086"
                     /db_xref="ASAP:ABE-0000414"
                     /db_xref="UniProtKB/Swiss-Prot:P0A8E5"
                     /db_xref="EcoGene:EG12605"
                     /db_xref="GeneID:944809"
                     /translation="MDYEFLRDITGVVKVRMSMGHEVVGHWFNEEVKENLALLDEVEQ
                     AAHALKGSERSWQRAGHEYTLWMDGEEVMVRANQLEFAGDEMEEGMNYYDEESLSLCG
                     VEDFLQVVAAYRNFVQQK"
     misc_feature    134388..134747
                     /gene="yacL"
                     /locus_tag="b0119"
                     /gene_synonym="ECK0118; JW0115"
                     /note="Uncharacterized protein conserved in bacteria
                     [Function unknown]; Region: COG3112"
                     /db_xref="CDD:225654"
     gene            complement(134788..135582)
                     /gene="speD"
                     /locus_tag="b0120"
                     /gene_synonym="ECK0119; JW0116"
                     /db_xref="EcoGene:EG10962"
                     /db_xref="GeneID:947719"
     CDS             complement(134788..135582)
                     /gene="speD"
                     /locus_tag="b0120"
                     /gene_synonym="ECK0119; JW0116"
                     /EC_number="4.1.1.50"
                     /function="enzyme; Central intermediary metabolism:
                     Polyamine biosynthesis"
                     /experiment="N-terminus verified by Edman degradation:
                     PMID 3546296"
                     /GO_process="GO:0006596 - polyamine biosynthetic process"
                     /codon_start=1
                     /transl_table=11
                     /product="S-adenosylmethionine decarboxylase"
                     /protein_id="NP_414662.1"
                     /db_xref="GI:16128113"
                     /db_xref="ASAP:ABE-0000416"
                     /db_xref="UniProtKB/Swiss-Prot:P0A7F6"
                     /db_xref="EcoGene:EG10962"
                     /db_xref="GeneID:947719"
                     /translation="MKKLKLHGFNNLTKSLSFCIYDICYAKTAEERDGYIAYIDELYN
                     ANRLTEILSETCSIIGANILNIARQDYEPQGASVTILVSEEPVDPKLIDKTEHPGPLP
                     ETVVAHLDKSHICVHTYPESHPEGGLCTFRADIEVSTCGVISPLKALNYLIHQLESDI
                     VTIDYRVRGFTRDINGMKHFIDHEINSIQNFMSDDMKALYDMVDVNVYQENIFHTKML
                     LKEFDLKHYMFHTKPEDLTDSERQEITAALWKEMREIYYGRNMPAV"
     misc_feature    complement(134791..135582)
                     /gene="speD"
                     /locus_tag="b0120"
                     /gene_synonym="ECK0119; JW0116"
                     /note="S-adenosylmethionine decarboxylase; Provisional;
                     Region: PRK05462"
                     /db_xref="CDD:235480"
     gene            complement(135598..136464)
                     /gene="speE"
                     /locus_tag="b0121"
                     /gene_synonym="ECK0120; JW0117"
                     /db_xref="EcoGene:EG10963"
                     /db_xref="GeneID:947726"
     CDS             complement(135598..136464)
                     /gene="speE"
                     /locus_tag="b0121"
                     /gene_synonym="ECK0120; JW0117"
                     /EC_number="2.5.1.16"
                     /function="enzyme; Central intermediary metabolism:
                     Polyamine biosynthesis"
                     /GO_process="GO:0006596 - polyamine biosynthetic process"
                     /note="spermidine synthase = putrescine
                     aminopropyltransferase"
                     /codon_start=1
                     /transl_table=11
                     /product="spermidine synthase (putrescine
                     aminopropyltransferase)"
                     /protein_id="NP_414663.1"
                     /db_xref="GI:16128114"
                     /db_xref="ASAP:ABE-0000418"
                     /db_xref="UniProtKB/Swiss-Prot:P09158"
                     /db_xref="EcoGene:EG10963"
                     /db_xref="GeneID:947726"
                     /translation="MAEKKQWHETLHDQFGQYFAVDNVLYHEKTDHQDLIIFENAAFG
                     RVMALDGVVQTTERDEFIYHEMMTHVPLLAHGHAKHVLIIGGGDGAMLREVTRHKNVE
                     SITMVEIDAGVVSFCRQYLPNHNAGSYDDPRFKLVIDDGVNFVNQTSQTFDVIISDCT
                     DPIGPGESLFTSAFYEGCKRCLNPGGIFVAQNGVCFLQQEEAIDSHRKLSHYFSDVGF
                     YQAAIPTYYGGIMTFAWATDNDALRHLSTEIIQARFLASGLKCRYYNPAIHTAAFALP
                     QYLQDALASQPS"
     misc_feature    complement(135892..136224)
                     /gene="speE"
                     /locus_tag="b0121"
                     /gene_synonym="ECK0120; JW0117"
                     /note="S-adenosylmethionine-dependent methyltransferases
                     (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes
                     that use S-adenosyl-L-methionine (SAM or AdoMet) as a
                     substrate for methyltransfer, creating the product
                     S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases;
                     cd02440"
                     /db_xref="CDD:100107"
     misc_feature    complement(order(135991..135993,136042..136050,
                     136138..136143,136195..136215))
                     /gene="speE"
                     /locus_tag="b0121"
                     /gene_synonym="ECK0120; JW0117"
                     /note="S-adenosylmethionine binding site [chemical
                     binding]; other site"
                     /db_xref="CDD:100107"
     gene            complement(136570..136917)
                     /gene="yacC"
                     /locus_tag="b0122"
                     /gene_synonym="ECK0121; gspS; JW0118"
                     /db_xref="EcoGene:EG11089"
                     /db_xref="GeneID:948472"
     CDS             complement(136570..136917)
                     /gene="yacC"
                     /locus_tag="b0122"
                     /gene_synonym="ECK0121; gspS; JW0118"
                     /codon_start=1
                     /transl_table=11
                     /product="PulS_OutS family protein"
                     /protein_id="NP_414664.4"
                     /db_xref="GI:90111087"
                     /db_xref="ASAP:ABE-0000423"
                     /db_xref="UniProtKB/Swiss-Prot:P0AA95"
                     /db_xref="EcoGene:EG11089"
                     /db_xref="GeneID:948472"
                     /translation="MKTFFRTVLFGSLMAVCANSYALSESEAEDMADLTAVFVFLKND
                     CGYQNLPNGQIRRALVFFAQQNQWDLSNYDTFDMKALGEDSYRDLSGIGIPVAKKCKA
                     LARDSLSLLAYVK"
     misc_feature    complement(136603..>136833)
                     /gene="yacC"
                     /locus_tag="b0122"
                     /gene_synonym="ECK0121; gspS; JW0118"
                     /note="Bacterial chaperone lipoprotein (PulS_OutS);
                     Region: PulS_OutS; cl09898"
                     /db_xref="CDD:263908"
     gene            137083..138633
                     /gene="cueO"
                     /locus_tag="b0123"
                     /gene_synonym="cuiD; ECK0122; JW0119; yacK"
                     /db_xref="EcoGene:EG12318"
                     /db_xref="GeneID:947736"
     CDS             137083..138633
                     /gene="cueO"
                     /locus_tag="b0123"
                     /gene_synonym="cuiD; ECK0122; JW0119; yacK"
                     /codon_start=1
                     /transl_table=11
                     /product="multicopper oxidase (laccase)"
                     /protein_id="NP_414665.1"
                     /db_xref="GI:16128116"
                     /db_xref="ASAP:ABE-0000430"
                     /db_xref="UniProtKB/Swiss-Prot:P36649"
                     /db_xref="EcoGene:EG12318"
                     /db_xref="GeneID:947736"
                     /translation="MQRRDFLKYSVALGVASALPLWSRAVFAAERPTLPIPDLLTTDA
                     RNRIQLTIGAGQSTFGGKTATTWGYNGNLLGPAVKLQRGKAVTVDIYNQLTEETTLHW
                     HGLEVPGEVDGGPQGIIPPGGKRSVTLNVDQPAATCWFHPHQHGKTGRQVAMGLAGLV
                     VIEDDEILKLMLPKQWGIDDVPVIVQDKKFSADGQIDYQLDVMTAAVGWFGDTLLTNG
                     AIYPQHAAPRGWLRLRLLNGCNARSLNFATSDNRPLYVIASDGGLLPEPVKVSELPVL
                     MGERFEVLVEVNDNKPFDLVTLPVSQMGMAIAPFDKPHPVMRIQPIAISASGALPDTL
                     SSLPALPSLEGLTVRKLQLSMDPMLDMMGMQMLMEKYGDQAMAGMDHSQMMGHMGHGN
                     MNHMNHGGKFDFHHANKINGQAFDMNKPMFAAAKGQYERWVISGVGDMMLHPFHIHGT
                     QFRILSENGKPPAAHRAGWKDTVKVEGNVSEVLVKFNHDAPKEHAYMAHCHLLEHEDT
                     GMMLGFTV"
     misc_feature    137083..138630
                     /gene="cueO"
                     /locus_tag="b0123"
                     /gene_synonym="cuiD; ECK0122; JW0119; yacK"
                     /note="multicopper oxidase; Provisional; Region: PRK10965"
                     /db_xref="CDD:236810"
     misc_feature    137221..137574
                     /gene="cueO"
                     /locus_tag="b0123"
                     /gene_synonym="cuiD; ECK0122; JW0119; yacK"
                     /note="The first Cupredoxin domain of the multicopper
                     oxidase CueO, the cell division protein FtsP, and similar
                     proteins; Region: CuRO_1_CueO_FtsP; cd04232"
                     /db_xref="CDD:259894"
     misc_feature    order(137266..137280,137299..137304,137311..137313,
                     137389..137394,137485..137499,137527..137532,
                     137536..137544,137557..137559,137563..137565)
                     /gene="cueO"
                     /locus_tag="b0123"
                     /gene_synonym="cuiD; ECK0122; JW0119; yacK"
                     /note="Domain 2 interface [polypeptide binding]; other
                     site"
                     /db_xref="CDD:259894"
     misc_feature    order(137383..137385,137389..137394,137398..137412,
                     137416..137418,137425..137430,137497..137499,
                     137503..137505,137509..137511,137515..137529,
                     137536..137538)
                     /gene="cueO"
                     /locus_tag="b0123"
                     /gene_synonym="cuiD; ECK0122; JW0119; yacK"
                     /note="Domain 3 interface [polypeptide binding]; other
                     site"
                     /db_xref="CDD:259894"
     misc_feature    order(137383..137385,137389..137391,137503..137505,
                     137509..137511)
                     /gene="cueO"
                     /locus_tag="b0123"
                     /gene_synonym="cuiD; ECK0122; JW0119; yacK"
                     /note="trinuclear Cu binding site [ion binding]; other
                     site"
                     /db_xref="CDD:259894"
     misc_feature    137617..138045
                     /gene="cueO"
                     /locus_tag="b0123"
                     /gene_synonym="cuiD; ECK0122; JW0119; yacK"
                     /note="The second Cupredoxin domain of the multicopper
                     oxidase CueO, the cell division protein FtsP, and similar
                     proteins; Region: CuRO_2_CueO_FtsP; cd13867"
                     /db_xref="CDD:259935"
     misc_feature    order(137623..137634,137644..137646,137719..137721,
                     137728..137739,137749..137751,137776..137778,
                     137782..137784,137788..137790,137860..137868,
                     137914..137916,137920..137922,138025..138027,
                     138031..138036)
                     /gene="cueO"
                     /locus_tag="b0123"
                     /gene_synonym="cuiD; ECK0122; JW0119; yacK"
                     /note="Domain 1 interface [polypeptide binding]; other
                     site"
                     /db_xref="CDD:259935"
     misc_feature    order(137803..137805,137809..137811,137848..137853,
                     137857..137871,137878..137886,137890..137892,
                     137902..137904,137908..137925)
                     /gene="cueO"
                     /locus_tag="b0123"
                     /gene_synonym="cuiD; ECK0122; JW0119; yacK"
                     /note="Domain 3 interface [polypeptide binding]; other
                     site"
                     /db_xref="CDD:259935"
     misc_feature    138298..138630
                     /gene="cueO"
                     /locus_tag="b0123"
                     /gene_synonym="cuiD; ECK0122; JW0119; yacK"
                     /note="The third Cupredoxin domain of the multicopper
                     oxidase CueO, the cell division protein FtsP, and similar
                     proteins; Region: CuRO_3_CueO_FtsP; cd13890"
                     /db_xref="CDD:259957"
     misc_feature    order(138304..138306,138403..138408,138412..138414,
                     138433..138435,138475..138480,138487..138498,
                     138502..138504,138583..138597,138604..138606)
                     /gene="cueO"
                     /locus_tag="b0123"
                     /gene_synonym="cuiD; ECK0122; JW0119; yacK"
                     /note="Domain 2 interface [polypeptide binding]; other
                     site"
                     /db_xref="CDD:259957"
     misc_feature    order(138325..138327,138331..138333,138418..138420,
                     138424..138426,138430..138435,138493..138495,
                     138544..138546,138562..138573,138577..138579,
                     138583..138585,138589..138594,138598..138603,
                     138613..138615)
                     /gene="cueO"
                     /locus_tag="b0123"
                     /gene_synonym="cuiD; ECK0122; JW0119; yacK"
                     /note="Domain 1 interface [polypeptide binding]; other
                     site"
                     /db_xref="CDD:259957"
     misc_feature    order(138409..138411,138580..138582,138595..138597,
                     138610..138612)
                     /gene="cueO"
                     /locus_tag="b0123"
                     /gene_synonym="cuiD; ECK0122; JW0119; yacK"
                     /note="Type 1 (T1) Cu binding site [ion binding]; other
                     site"
                     /db_xref="CDD:259957"
     misc_feature    order(138418..138420,138424..138426,138577..138579,
                     138583..138585)
                     /gene="cueO"
                     /locus_tag="b0123"
                     /gene_synonym="cuiD; ECK0122; JW0119; yacK"
                     /note="trinuclear Cu binding site [ion binding]; other
                     site"
                     /db_xref="CDD:259957"
     repeat_region   138699..138796
                     /note="RIP10 (repetitive extragenic palindromic) element;
                     contains 2 REP sequences and 1 IHF site"
     gene            complement(138835..141225)
                     /gene="gcd"
                     /locus_tag="b0124"
                     /gene_synonym="ECK0123; JW0120"
                     /db_xref="EcoGene:EG10369"
                     /db_xref="GeneID:944830"
     CDS             complement(138835..141225)
                     /gene="gcd"
                     /locus_tag="b0124"
                     /gene_synonym="ECK0123; JW0120"
                     /EC_number="1.1.5.2"
                     /function="enzyme; Degradation of small molecules: Carbon
                     compounds"
                     /experiment="N-terminus verified by Edman degradation:
                     PMID 8509415"
                     /GO_component="GO:0009274 - peptidoglycan-based cell wall"
                     /GO_component="GO:0019866 - organelle inner membrane"
                     /GO_process="GO:0006006 - glucose metabolic process"
                     /GO_process="GO:0016052 - carbohydrate catabolic process"
                     /codon_start=1
                     /transl_table=11
                     /product="glucose dehydrogenase"
                     /protein_id="NP_414666.1"
                     /db_xref="GI:16128117"
                     /db_xref="ASAP:ABE-0000433"
                     /db_xref="UniProtKB/Swiss-Prot:P15877"
                     /db_xref="EcoGene:EG10369"
                     /db_xref="GeneID:944830"
                     /translation="MAINNTGSRRLLVTLTALFAALCGLYLLIGGGWLVAIGGSWYYP
                     IAGLVMLGVAWMLWRSKRAALWLYAALLLGTMIWGVWEVGFDFWALTPRSDILVFFGI
                     WLILPFVWRRLVIPASGAVAALVVALLISGGILTWAGFNDPQEINGTLSADATPAEAI
                     SPVADQDWPAYGRNQEGQRFSPLKQINADNVHNLKEAWVFRTGDVKQPNDPGEITNEV
                     TPIKVGDTLYLCTAHQRLFALDAASGKEKWHYDPELKTNESFQHVTCRGVSYHEAKAE
                     TASPEVMADCPRRIILPVNDGRLIAINAENGKLCETFANKGVLNLQSNMPDTKPGLYE
                     PTSPPIITDKTIVMAGSVTDNFSTRETSGVIRGFDVNTGELLWAFDPGAKDPNAIPSD
                     EHTFTFNSPNSWAPAAYDAKLDLVYLPMGVTTPDIWGGNRTPEQERYASSILALNATT
                     GKLAWSYQTVHHDLWDMDLPAQPTLADITVNGQKVPVIYAPAKTGNIFVLDRRNGELV
                     VPAPEKPVPQGAAKGDYVTPTQPFSELSFRPTKDLSGADMWGATMFDQLVCRVMFHQM
                     RYEGIFTPPSEQGTLVFPGNLGMFEWGGISVDPNREVAIANPMALPFVSKLIPRGPGN
                     PMEQPKDAKGTGTESGIQPQYGVPYGVTLNPFLSPFGLPCKQPAWGYISALDLKTNEV
                     VWKKRIGTPQDSMPFPMPVPVPFNMGMPMLGGPISTAGNVLFIAATADNYLRAYNMSN
                     GEKLWQGRLPAGGQATPMTYEVNGKQYVVISAGGHGSFGTKMGDYIVAYALPDDVK"
     misc_feature    complement(138847..141195)
                     /gene="gcd"
                     /locus_tag="b0124"
                     /gene_synonym="ECK0123; JW0120"
                     /note="Glucose dehydrogenase [Carbohydrate transport and
                     metabolism]; Region: Gcd; COG4993"
                     /db_xref="CDD:227326"
     misc_feature    complement(138853..140724)
                     /gene="gcd"
                     /locus_tag="b0124"
                     /gene_synonym="ECK0123; JW0120"
                     /note="Membrane-bound PQQ-dependent glucose dehydrogenase;
                     Region: PQQ_mGDH; cd10280"
                     /db_xref="CDD:199838"
     misc_feature    complement(order(138856..138858,138862..138864,
                     138991..138993,139000..139008,139015..139017,
                     139021..139023,139174..139176,139183..139191,
                     139198..139200,139204..139206,139699..139701,
                     139708..139716,139723..139725,139729..139731,
                     139861..139863,139870..139878,139885..139887,
                     139891..139893,140095..140097,140104..140112,
                     140119..140121,140125..140127,140293..140295,
                     140302..140310,140317..140319,140323..140325,
                     140482..140484,140491..140499,140506..140508,
                     140512..140514,140632..140634,140641..140649))
                     /gene="gcd"
                     /locus_tag="b0124"
                     /gene_synonym="ECK0123; JW0120"
                     /note="Trp docking motif [polypeptide binding]; other
                     site"
                     /db_xref="CDD:199838"
     misc_feature    complement(order(139090..139092,139747..139749,
                     140014..140016,140170..140175,140218..140220,
                     140428..140430,140443..140448,140575..140577))
                     /gene="gcd"
                     /locus_tag="b0124"
                     /gene_synonym="ECK0123; JW0120"
                     /note="putative active site [active]"
                     /db_xref="CDD:199838"
     gene            141431..141967
                     /gene="hpt"
                     /locus_tag="b0125"
                     /gene_synonym="ECK0124; JW5009"
                     /db_xref="EcoGene:EG20098"
                     /db_xref="GeneID:946624"
     CDS             141431..141967
                     /gene="hpt"
                     /locus_tag="b0125"
                     /gene_synonym="ECK0124; JW5009"
                     /EC_number="2.4.2.8"
                     /function="enzyme; Salvage of nucleosides and nucleotides"
                     /GO_component="GO:0005737 - cytoplasm"
                     /GO_process="GO:0015949 - nucleobase, nucleoside and
                     nucleotide interconversion"
                     /codon_start=1
                     /transl_table=11
                     /product="hypoxanthine phosphoribosyltransferase"
                     /protein_id="NP_414667.4"
                     /db_xref="GI:90111088"
                     /db_xref="ASAP:ABE-0000440"
                     /db_xref="UniProtKB/Swiss-Prot:P0A9M2"
                     /db_xref="EcoGene:EG20098"
                     /db_xref="GeneID:946624"
                     /translation="MKHTVEVMIPEAEIKARIAELGRQITERYKDSGSDMVLVGLLRG
                     SFMFMADLCREVQVSHEVDFMTASSYGSGMSTTRDVKILKDLDEDIRGKDVLIVEDII
                     DSGNTLSKVREILSLREPKSLAICTLLDKPSRREVNVPVEFIGFSIPDEFVVGYGIDY
                     AQRYRHLPYIGKVILLDE"
     misc_feature    141482..141838
                     /gene="hpt"
                     /locus_tag="b0125"
                     /gene_synonym="ECK0124; JW5009"
                     /note="Phosphoribosyl transferase (PRT)-type I domain;
                     Region: PRTases_typeI; cd06223"
                     /db_xref="CDD:206754"
     misc_feature    order(141554..141556,141560..141562,141725..141733,
                     141737..141751,141821..141823)
                     /gene="hpt"
                     /locus_tag="b0125"
                     /gene_synonym="ECK0124; JW5009"
                     /note="active site"
                     /db_xref="CDD:206754"
     repeat_region   141978..141998
                     /note="REP11 (repetitive extragenic palindromic) element;
                     contains 1 REP sequences"
     gene            complement(142008..142670)
                     /gene="can"
                     /locus_tag="b0126"
                     /gene_synonym="ECK0125; JW0122; yadF"
                     /db_xref="EcoGene:EG12319"
                     /db_xref="GeneID:944832"
     CDS             complement(142008..142670)
                     /gene="can"
                     /locus_tag="b0126"
                     /gene_synonym="ECK0125; JW0122; yadF"
                     /EC_number="4.2.1.1"
                     /function="enzyme; Central intermediary metabolism: Pool,
                     multipurpose conversions"
                     /note="putative carbonic anhdrase"
                     /codon_start=1
                     /transl_table=11
                     /product="carbonic anhydrase"
                     /protein_id="NP_414668.1"
                     /db_xref="GI:16128119"
                     /db_xref="ASAP:ABE-0000442"
                     /db_xref="UniProtKB/Swiss-Prot:P61517"
                     /db_xref="EcoGene:EG12319"
                     /db_xref="GeneID:944832"
                     /translation="MKDIDTLISNNALWSKMLVEEDPGFFEKLAQAQKPRFLWIGCSD
                     SRVPAERLTGLEPGELFVHRNVANLVIHTDLNCLSVVQYAVDVLEVEHIIICGHYGCG
                     GVQAAVENPELGLINNWLLHIRDIWFKHSSLLGEMPQERRLDTLCELNVMEQVYNLGH
                     STIMQSAWKRGQKVTIHGWAYGIHDGLLRDLDVTATNRETLEQRYRHGISNLKLKHAN
                     HK"
     misc_feature    complement(142098..142640)
                     /gene="can"
                     /locus_tag="b0126"
                     /gene_synonym="ECK0125; JW0122; yadF"
                     /note="Carbonic anhydrases (CA) are zinc-containing
                     enzymes that catalyze the reversible hydration of carbon
                     dioxide in a two-step mechanism in which the nucleophilic
                     attack of a zinc-bound hydroxide ion on carbon dioxide is
                     followed by the regeneration of an...; Region:
                     beta_CA_cladeA; cd00883"
                     /db_xref="CDD:238448"
     misc_feature    complement(order(142128..142130,142368..142370,
                     142377..142379,142407..142409,142422..142424,
                     142488..142490,142497..142499,142533..142541,
                     142545..142547,142566..142568,142572..142574))
                     /gene="can"
                     /locus_tag="b0126"
                     /gene_synonym="ECK0125; JW0122; yadF"
                     /note="active site clefts [active]"
                     /db_xref="CDD:238448"
     misc_feature    complement(order(142368..142370,142377..142379,
                     142539..142541,142545..142547))
                     /gene="can"
                     /locus_tag="b0126"
                     /gene_synonym="ECK0125; JW0122; yadF"
                     /note="zinc binding site [ion binding]; other site"
                     /db_xref="CDD:238448"
     misc_feature    complement(order(142107..142109,142113..142115,
                     142119..142124,142128..142130,142314..142316,
                     142422..142427,142434..142439,142479..142481,
                     142485..142487,142491..142499,142512..142514,
                     142518..142523,142527..142529,142533..142544))
                     /gene="can"
                     /locus_tag="b0126"
                     /gene_synonym="ECK0125; JW0122; yadF"
                     /note="dimer interface [polypeptide binding]; other site"
                     /db_xref="CDD:238448"
     gene            142779..143705
                     /gene="yadG"
                     /locus_tag="b0127"
                     /gene_synonym="ECK0126; JW0123"
                     /db_xref="EcoGene:EG12320"
                     /db_xref="GeneID:944833"
     CDS             142779..143705
                     /gene="yadG"
                     /locus_tag="b0127"
                     /gene_synonym="ECK0126; JW0123"
                     /function="putative transport; Not classified"
                     /GO_component="GO:0005737 - cytoplasm"
                     /note="putative ATP-binding component of a transport
                     system"
                     /codon_start=1
                     /transl_table=11
                     /product="putative ABC transporter ATPase"
                     /protein_id="NP_414669.1"
                     /db_xref="GI:16128120"
                     /db_xref="ASAP:ABE-0000447"
                     /db_xref="UniProtKB/Swiss-Prot:P36879"
                     /db_xref="EcoGene:EG12320"
                     /db_xref="GeneID:944833"
                     /translation="MTIALELQQLKKTYPGGVQALRGIDLQVEAGDFYALLGPNGAGK
                     STTIGIISSLVNKTSGRVSVFGYDLEKDVVNAKRQLGLVPQEFNFNPFETVQQIVVNQ
                     AGYYGVERKEAYIRSEKYLKQLDLWGKRNERARMLSGGMKRRLMIARALMHEPKLLIL
                     DEPTAGVDIELRRSMWGFLKDLNDKGTTIILTTHYLEEAEMLCRNIGIIQHGELVENT
                     SMKALLAKLKSETFILDLAPKSPLPKLDGYQYRLVDTATLEVEVLREQGINSVFTQLS
                     EQGIQVLSMRNKANRLEELFVSLVNEKQGDRA"
     misc_feature    142779..143684
                     /gene="yadG"
                     /locus_tag="b0127"
                     /gene_synonym="ECK0126; JW0123"
                     /note="ABC-type multidrug transport system, ATPase
                     component [Defense mechanisms]; Region: CcmA; COG1131"
                     /db_xref="CDD:224054"
     misc_feature    142791..143420
                     /gene="yadG"
                     /locus_tag="b0127"
                     /gene_synonym="ECK0126; JW0123"
                     /note="ATP-binding cassette domain of the drug resistance
                     transporter and related proteins, subfamily A; Region:
                     ABC_DR_subfamily_A; cd03230"
                     /db_xref="CDD:213197"
     misc_feature    142890..142913
                     /gene="yadG"
                     /locus_tag="b0127"
                     /gene_synonym="ECK0126; JW0123"
                     /note="Walker A/P-loop; other site"
                     /db_xref="CDD:213197"
     misc_feature    order(142899..142904,142908..142916,143031..143033,
                     143259..143264,143358..143360)
                     /gene="yadG"
                     /locus_tag="b0127"
                     /gene_synonym="ECK0126; JW0123"
                     /note="ATP binding site [chemical binding]; other site"
                     /db_xref="CDD:213197"
     misc_feature    143022..143033
                     /gene="yadG"
                     /locus_tag="b0127"
                     /gene_synonym="ECK0126; JW0123"
                     /note="Q-loop/lid; other site"
                     /db_xref="CDD:213197"
     misc_feature    143187..143216
                     /gene="yadG"
                     /locus_tag="b0127"
                     /gene_synonym="ECK0126; JW0123"
                     /note="ABC transporter signature motif; other site"
                     /db_xref="CDD:213197"
     misc_feature    143247..143264
                     /gene="yadG"
                     /locus_tag="b0127"
                     /gene_synonym="ECK0126; JW0123"
                     /note="Walker B; other site"
                     /db_xref="CDD:213197"
     misc_feature    143271..143282
                     /gene="yadG"
                     /locus_tag="b0127"
                     /gene_synonym="ECK0126; JW0123"
                     /note="D-loop; other site"
                     /db_xref="CDD:213197"
     misc_feature    143346..143366
                     /gene="yadG"
                     /locus_tag="b0127"
                     /gene_synonym="ECK0126; JW0123"
                     /note="H-loop/switch region; other site"
                     /db_xref="CDD:213197"
     gene            143702..144472
                     /gene="yadH"
                     /locus_tag="b0128"
                     /gene_synonym="ECK0127; JW0124"
                     /db_xref="EcoGene:EG12321"
                     /db_xref="GeneID:944836"
     CDS             143702..144472
                     /gene="yadH"
                     /locus_tag="b0128"
                     /gene_synonym="ECK0127; JW0124"
                     /GO_component="GO:0009274 - peptidoglycan-based cell wall"
                     /GO_component="GO:0019866 - organelle inner membrane"
                     /codon_start=1
                     /transl_table=11
                     /product="putative ABC transporter permease"
                     /protein_id="NP_414670.1"
                     /db_xref="GI:16128121"
                     /db_xref="ASAP:ABE-0000450"
                     /db_xref="UniProtKB/Swiss-Prot:P0AFN6"
                     /db_xref="EcoGene:EG12321"
                     /db_xref="GeneID:944836"
                     /translation="MMHLYWVALKSIWAKEIHRFMRIWVQTLVPPVITMTLYFIIFGN
                     LIGSRIGDMHGFSYMQFIVPGLIMMSVITNAYANVASSFFGAKFQRNIEELLVAPVPT
                     HVIIAGYVGGGVARGLFVGILVTAISLFFVPFQVHSWVFVALTLVLTAVLFSLAGLLN
                     GVFAKTFDDISLVPTFVLTPLTYLGGVFYSLTLLPPFWQGLSHLNPIVYMISGFRYGF
                     LGINDVPLVTTFGVLVVFIVAFYLICWSLIQRGRGLRS"
     misc_feature    143702..144469
                     /gene="yadH"
                     /locus_tag="b0128"
                     /gene_synonym="ECK0127; JW0124"
                     /note="inner membrane transport permease; Provisional;
                     Region: PRK15066"
                     /db_xref="CDD:237896"
     misc_feature    143702..144466
                     /gene="yadH"
                     /locus_tag="b0128"
                     /gene_synonym="ECK0127; JW0124"
                     /note="ABC-type multidrug transport system, permease
                     component [Defense mechanisms]; Region: COG0842"
                     /db_xref="CDD:223912"
     gene            144577..145017
                     /gene="yadI"
                     /locus_tag="b0129"
                     /gene_synonym="agaX; ECK0128; JW0125"
                     /db_xref="EcoGene:EG12322"
                     /db_xref="GeneID:947397"
     CDS             144577..145017
                     /gene="yadI"
                     /locus_tag="b0129"
                     /gene_synonym="agaX; ECK0128; JW0125"
                     /function="putative transport; Not classified"
                     /GO_process="GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system"
                     /note="putative PTS enzyme II B component"
                     /codon_start=1
                     /transl_table=11
                     /product="putative PTS Enzyme IIA"
                     /protein_id="NP_414671.1"
                     /db_xref="GI:16128122"
                     /db_xref="ASAP:ABE-0000453"
                     /db_xref="UniProtKB/Swiss-Prot:P36881"
                     /db_xref="EcoGene:EG12322"
                     /db_xref="GeneID:947397"
                     /translation="MLGWVITCHDDRAQEILDALEKKHGALLQCRAVNFWRGLSSNML
                     SRMMCDALHEADSGEGVIFLTDIAGAPPYRVASLLSHKHSRCEVISGVTLPLIEQMMA
                     CRETMTSSEFRERIVELGAPEVSSLWHQQQKNPPFVLKHNLYEY"
     misc_feature    144583..144936
                     /gene="yadI"
                     /locus_tag="b0129"
                     /gene_synonym="agaX; ECK0128; JW0125"
                     /note="PTS_IIA, PTS system, mannose/sorbose specific IIA
                     subunit. The bacterial phosphoenolpyruvate: sugar
                     phosphotransferase system (PTS) is a multi-protein system
                     involved in the regulation of a variety of metabolic and
                     transcriptional processes. This family...; Region:
                     PTS_IIA_man; cd00006"
                     /db_xref="CDD:237978"
     misc_feature    order(144601..144603,144643..144648,144679..144681,
                     144787..144789,144880..144882)
                     /gene="yadI"
                     /locus_tag="b0129"
                     /gene_synonym="agaX; ECK0128; JW0125"
                     /note="active pocket/dimerization site"
                     /db_xref="CDD:237978"
     misc_feature    order(144601..144603,144772..144774,144787..144789)
                     /gene="yadI"
                     /locus_tag="b0129"
                     /gene_synonym="agaX; ECK0128; JW0125"
                     /note="active site"
                     /db_xref="CDD:237978"
     misc_feature    144601..144603
                     /gene="yadI"
                     /locus_tag="b0129"
                     /gene_synonym="agaX; ECK0128; JW0125"
                     /note="phosphorylation site [posttranslational
                     modification]"
                     /db_xref="CDD:237978"
     gene            145081..146310
                     /gene="yadE"
                     /locus_tag="b0130"
                     /gene_synonym="ECK0129; JW0126"
                     /db_xref="EcoGene:EG11749"
                     /db_xref="GeneID:946536"
     CDS             145081..146310
                     /gene="yadE"
                     /locus_tag="b0130"
                     /gene_synonym="ECK0129; JW0126"
                     /note="conserved hypothetical protein"
                     /codon_start=1
                     /transl_table=11
                     /product="putative polysaccharide deacetylase lipoprotein"
                     /protein_id="NP_414672.1"
                     /db_xref="GI:16128123"
                     /db_xref="ASAP:ABE-0000457"
                     /db_xref="UniProtKB/Swiss-Prot:P31666"
                     /db_xref="EcoGene:EG11749"
                     /db_xref="GeneID:946536"
                     /translation="MYKQAVILLLMLFTASVSAALPARYMQTIENAAVWAQIGDKMVT
                     VGNIRAGQIIAVEPTAASYYAFNFGFGKGFIDKGHLEPVQGRQKVEDGLGDLNKPLSN
                     QNLVTWKDTPVYNAPSAGSAPFGVLADNLRYPILHKLKDRLNQTWYQIRIGDRLAYIS
                     ALDAQPDNGLSVLTYHHILRDEENTRFRHTSTTTSVRAFNNQMAWLRDRGYATLSMVQ
                     LEGYVKNKINLPARAVVITFDDGLKSVSRYAYPVLKQYGMKATAFIVTSRIKRHPQKW
                     NPKSLQFMSVSELNEIRDVFDFQSHTHFLHRVDGYRRPILLSRSEHNILFDFARSRRA
                     LAQFNPHVWYLSYPFGGFNDNAVKAANDAGFHLAVTTMKGKVKPGDNPLLLKRLYILR
                     TDSLETMSRLVSNQPQG"
     misc_feature    145768..146277
                     /gene="yadE"
                     /locus_tag="b0130"
                     /gene_synonym="ECK0129; JW0126"
                     /note="Putative catalytic polysaccharide deacetylase
                     domain of uncharacterized protein yadE and similar
                     proteins; Region: CE4_yadE_5s; cd10966"
                     /db_xref="CDD:213024"
     misc_feature    order(145795..145800,145981..145983,145996..145998,
                     146122..146130)
                     /gene="yadE"
                     /locus_tag="b0130"
                     /gene_synonym="ECK0129; JW0126"
                     /note="putative active site [active]"
                     /db_xref="CDD:213024"
     misc_feature    order(145798..145800,145981..145983,145996..145998)
                     /gene="yadE"
                     /locus_tag="b0130"
                     /gene_synonym="ECK0129; JW0126"
                     /note="putative metal binding site [ion binding]; other
                     site"
                     /db_xref="CDD:213024"
     gene            complement(146314..146694)
                     /gene="panD"
                     /locus_tag="b0131"
                     /gene_synonym="ECK0130; JW0127"
                     /db_xref="EcoGene:EG11747"
                     /db_xref="GeneID:945686"
     CDS             complement(146314..146694)
                     /gene="panD"
                     /locus_tag="b0131"
                     /gene_synonym="ECK0130; JW0127"
                     /EC_number="4.1.1.11"
                     /function="enzyme; Biosynthesis of cofactors, carriers:
                     Pantothenate"
                     /experiment="N-terminus verified by Edman degradation:
                     PMID 9169598"
                     /GO_component="GO:0005737 - cytoplasm"
                     /GO_process="GO:0015937 - coenzyme A biosynthetic process"
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate 1-decarboxylase"
                     /protein_id="NP_414673.1"
                     /db_xref="GI:16128124"
                     /db_xref="ASAP:ABE-0000459"
                     /db_xref="UniProtKB/Swiss-Prot:P0A790"
                     /db_xref="EcoGene:EG11747"
                     /db_xref="GeneID:945686"
                     /translation="MIRTMLQGKLHRVKVTHADLHYEGSCAIDQDFLDAAGILENEAI
                     DIWNVTNGKRFSTYAIAAERGSRIISVNGAAAHCASVGDIVIIASFVTMPDEEARTWR
                     PNVAYFEGDNEMKRTAKAIPVQVA"
     misc_feature    complement(146359..146688)
                     /gene="panD"
                     /locus_tag="b0131"
                     /gene_synonym="ECK0130; JW0127"
                     /note="Aspartate alpha-decarboxylase or L-aspartate
                     1-decarboxylase, a pyruvoyl group-dependent  decarboxylase
                     in beta-alanine production; Region: Asp_decarbox; cd06919"
                     /db_xref="CDD:132994"
     misc_feature    complement(order(146392..146394,146419..146427,
                     146437..146439,146461..146466,146470..146475,
                     146521..146535,146539..146541,146548..146550,
                     146554..146556,146566..146571,146578..146580,
                     146584..146586,146626..146637,146659..146664,
                     146668..146670,146674..146688))
                     /gene="panD"
                     /locus_tag="b0131"
                     /gene_synonym="ECK0130; JW0127"
                     /note="tetramerization interface [polypeptide binding];
                     other site"
                     /db_xref="CDD:132994"
     misc_feature    complement(order(146521..146523,146620..146625,
                     146662..146664,146668..146670))
                     /gene="panD"
                     /locus_tag="b0131"
                     /gene_synonym="ECK0130; JW0127"
                     /note="active site"
                     /db_xref="CDD:132994"
     gene            146968..147870
                     /gene="yadD"
                     /locus_tag="b0132"
                     /gene_synonym="ECK0131; JW5010"
                     /db_xref="EcoGene:EG11748"
                     /db_xref="GeneID:944781"
     CDS             146968..147870
                     /gene="yadD"
                     /locus_tag="b0132"
                     /gene_synonym="ECK0131; JW5010"
                     /codon_start=1
                     /transl_table=11
                     /product="transposase_31 family protein"
                     /protein_id="NP_414674.1"
                     /db_xref="GI:16128125"
                     /db_xref="ASAP:ABE-0000463"
                     /db_xref="UniProtKB/Swiss-Prot:P31665"
                     /db_xref="EcoGene:EG11748"
                     /db_xref="GeneID:944781"
                     /translation="MDAPSTTPHDAVFKQFLMHAETARDFLEIHLPVELRELCDLNTL
                     HLESGSFIEESLKGHSTDVLYSVQMQGNPGYLHVVIEHQSKPDKKMAFRMMRYSIAAM
                     HRHLEADHDKLPLVVPILFYQGEATPYPLSMCWFDMFYSPELARRVYNSPFPLVDITI
                     TPDDEIMQHRRIAILELLQKHIRQRDLMLLLEQLVTLIDEGYTSGSQLVAMQNYMLQR
                     GHTEQADLFYGVLRDRETGGESMMTLAQWFEEKGIEKGIQQGRQEVSQEFAQRLLSKG
                     MSREDVAEMANLPLAEIDKVINLI"
     misc_feature    146986..147846
                     /gene="yadD"
                     /locus_tag="b0132"
                     /gene_synonym="ECK0131; JW5010"
                     /note="Uncharacterized conserved protein [Function
                     unknown]; Region: COG5464"
                     /db_xref="CDD:227751"
     misc_feature    146986..147591
                     /gene="yadD"
                     /locus_tag="b0132"
                     /gene_synonym="ECK0131; JW5010"
                     /note="Putative transposase, YhgA-like; Region:
                     Transposase_31; pfam04754"
                     /db_xref="CDD:252779"
     gene            complement(147944..148795)
                     /gene="panC"
                     /locus_tag="b0133"
                     /gene_synonym="ECK0132; JW0129"
                     /db_xref="EcoGene:EG11746"
                     /db_xref="GeneID:944958"
     CDS             complement(147944..148795)
                     /gene="panC"
                     /locus_tag="b0133"
                     /gene_synonym="ECK0132; JW0129"
                     /EC_number="6.3.2.1"
                     /function="enzyme; Biosynthesis of cofactors, carriers:
                     Pantothenate"
                     /GO_component="GO:0005737 - cytoplasm"
                     /GO_process="GO:0015937 - coenzyme A biosynthetic process"
                     /codon_start=1
                     /transl_table=11
                     /product="pantothenate synthetase"
                     /protein_id="NP_414675.1"
                     /db_xref="GI:16128126"
                     /db_xref="ASAP:ABE-0000465"
                     /db_xref="UniProtKB/Swiss-Prot:P31663"
                     /db_xref="EcoGene:EG11746"
                     /db_xref="GeneID:944958"
                     /translation="MLIIETLPLLRQQIRRLRMEGKRVALVPTMGNLHDGHMKLVDEA
                     KARADVVVVSIFVNPMQFDRPEDLARYPRTLQEDCEKLNKRKVDLVFAPSVKEIYPNG
                     TETHTYVDVPGLSTMLEGASRPGHFRGVSTIVSKLFNLVQPDIACFGEKDFQQLALIR
                     KMVADMGFDIEIVGVPIMRAKDGLALSSRNGYLTAEQRKIAPGLYKVLSSIADKLQAG
                     ERDLDEIITIAGQELNEKGFRADDIQIRDADTLLEVSETSKRAVILVAAWLGDARLID
                     NKMVELA"
     misc_feature    complement(147965..148795)
                     /gene="panC"
                     /locus_tag="b0133"
                     /gene_synonym="ECK0132; JW0129"
                     /note="Pantoate-beta-alanine ligase; Region: PanC;
                     cd00560"
                     /db_xref="CDD:185673"
     misc_feature    complement(order(148229..148240,148262..148270,
                     148331..148333,148340..148345,148349..148354,
                     148394..148399,148406..148408,148583..148585,
                     148613..148615,148622..148624,148676..148678,
                     148685..148690,148694..148696,148703..148714))
                     /gene="panC"
                     /locus_tag="b0133"
                     /gene_synonym="ECK0132; JW0129"
                     /note="active site"
                     /db_xref="CDD:185673"
     misc_feature    complement(order(148238..148243,148262..148267,
                     148331..148333,148340..148345,148349..148354,
                     148394..148399,148613..148615,148676..148678,
                     148685..148687,148694..148696,148706..148714))
                     /gene="panC"
                     /locus_tag="b0133"
                     /gene_synonym="ECK0132; JW0129"
                     /note="ATP-binding site [chemical binding]; other site"
                     /db_xref="CDD:185673"
     misc_feature    complement(order(148331..148333,148385..148387,
                     148394..148399,148613..148615,148622..148624,
                     148706..148708,148712..148714))
                     /gene="panC"
                     /locus_tag="b0133"
                     /gene_synonym="ECK0132; JW0129"
                     /note="pantoate-binding site; other site"
                     /db_xref="CDD:185673"
     misc_feature    complement(148685..148696)
                     /gene="panC"
                     /locus_tag="b0133"
                     /gene_synonym="ECK0132; JW0129"
                     /note="HXXH motif; other site"
                     /db_xref="CDD:185673"
     gene            complement(148807..149601)
                     /gene="panB"
                     /locus_tag="b0134"
                     /gene_synonym="ECK0133; JW0130; panA"
                     /db_xref="EcoGene:EG11675"
                     /db_xref="GeneID:944839"
     CDS             complement(148807..149601)
                     /gene="panB"
                     /locus_tag="b0134"
                     /gene_synonym="ECK0133; JW0130; panA"
                     /EC_number="2.1.2.11"
                     /function="enzyme; Biosynthesis of cofactors, carriers:
                     Pantothenate"
                     /experiment="N-terminus verified by Edman degradation:
                     PMID 8096212,9298646"
                     /GO_component="GO:0005737 - cytoplasm"
                     /GO_process="GO:0015937 - coenzyme A biosynthetic process"
                     /codon_start=1
                     /transl_table=11
                     /product="3-methyl-2-oxobutanoate
                     hydroxymethyltransferase"
                     /protein_id="NP_414676.1"
                     /db_xref="GI:16128127"
                     /db_xref="ASAP:ABE-0000467"
                     /db_xref="UniProtKB/Swiss-Prot:P31057"
                     /db_xref="EcoGene:EG11675"
                     /db_xref="GeneID:944839"
                     /translation="MKPTTISLLQKYKQEKKRFATITAYDYSFAKLFADEGLNVMLVG
                     DSLGMTVQGHDSTLPVTVADIAYHTAAVRRGAPNCLLLADLPFMAYATPEQAFENAAT
                     VMRAGANMVKIEGGEWLVETVQMLTERAVPVCGHLGLTPQSVNIFGGYKVQGRGDEAG
                     DQLLSDALALEAAGAQLLVLECVPVELAKRITEALAIPVIGIGAGNVTDGQILVMHDA
                     FGITGGHIPKFAKNFLAETGDIRAAVRQYMAEVESGVYPGEEHSFH"
     misc_feature    complement(148831..149586)
                     /gene="panB"
                     /locus_tag="b0134"
                     /gene_synonym="ECK0133; JW0130; panA"
                     /note="Ketopantoate hydroxymethyltransferase (KPHMT) is
                     the first enzyme in the pantothenate biosynthesis pathway.
                     Ketopantoate hydroxymethyltransferase (KPHMT) catalyzes
                     the first committed step in the biosynthesis of
                     pantothenate (vitamin B5), which is a...; Region:
                     KPHMT-like; cd06557"
                     /db_xref="CDD:119342"
     misc_feature    complement(order(148879..148893,148900..148902,
                     148942..148947,148954..148956,149074..149076,
                     149158..149169,149173..149178,149206..149223,
                     149275..149277,149287..149292,149299..149301,
                     149311..149313,149338..149343,149380..149382,
                     149389..149391,149398..149403,149410..149412,
                     149425..149430,149440..149457,149461..149463,
                     149506..149508,149515..149526,149581..149586))
                     /gene="panB"
                     /locus_tag="b0134"
                     /gene_synonym="ECK0133; JW0130; panA"
                     /note="oligomerization interface [polypeptide binding];
                     other site"
                     /db_xref="CDD:119342"
     misc_feature    complement(order(148960..148962,148966..148968,
                     149059..149061,149179..149181,149194..149196,
                     149266..149268,149350..149352,149464..149472,
                     149476..149478,149533..149535))
                     /gene="panB"
                     /locus_tag="b0134"
                     /gene_synonym="ECK0133; JW0130; panA"
                     /note="active site"
                     /db_xref="CDD:119342"
     misc_feature    complement(order(149266..149268,149350..149352,
                     149467..149469))
                     /gene="panB"
                     /locus_tag="b0134"
                     /gene_synonym="ECK0133; JW0130; panA"
                     /note="metal binding site [ion binding]; metal-binding
                     site"
                     /db_xref="CDD:119342"
     gene            complement(149715..150953)
                     /gene="yadC"
                     /locus_tag="b0135"
                     /gene_synonym="ECK0134; JW0131"
                     /db_xref="EcoGene:EG11678"
                     /db_xref="GeneID:944837"
     CDS             complement(149715..150953)
                     /gene="yadC"
                     /locus_tag="b0135"
                     /gene_synonym="ECK0134; JW0131"
                     /function="putative structural component; Surface
                     structures"
                     /GO_component="GO:0009289 - pilus"
                     /note="putative fimbrial-like protein"
                     /codon_start=1
                     /transl_table=11
                     /product="putative fimbrial-like adhesin protein"
                     /protein_id="NP_414677.1"
                     /db_xref="GI:16128128"
                     /db_xref="ASAP:ABE-0000470"
                     /db_xref="UniProtKB/Swiss-Prot:P31058"
                     /db_xref="EcoGene:EG11678"
                     /db_xref="GeneID:944837"
                     /translation="MKTIFRYILFLALYSCCNTVSAYTSFIVGNNAGVDNYRGPSTAA
                     QMTFNYTSTASNLVFYKPTQLGPTGVKMYWSYLDTGTGGGILYCNTSGRANPGPITIE
                     NAMVYSGKDYGGHKLFNTSVPGLYYTMLISRVWSAYDTITDIQSPGIYIGDPSNQEFF
                     FSVTDSDLQTKGCNKADDYDKFWAIGGIVHNITVEFYTDTNFDPTLNQQVQLSSSSNY
                     LYSFKAYSPGTKVVDHSNHIYVNFTLNNVKLTLPTCFTSILTGPSVNGSTVRMGEYSS
                     GTIKNGASPVPFDISLQNCIRVRNIETKLVTGKVGTQNTQLLGNTLTGSTAAKGVGVL
                     IEGLATSKNPLMTLKPNDTNSVYIDYETEDDTSDGVYPNQGNGTSQPLHFQATLKQDG
                     NIAIEPGEFKATSTFQVTYP"
     misc_feature    complement(149718..150953)
                     /gene="yadC"
                     /locus_tag="b0135"
                     /gene_synonym="ECK0134; JW0131"
                     /note="putative fimbrial-like adhesin protein;
                     Provisional; Region: PRK09723"
                     /db_xref="CDD:236617"
     gene            complement(151003..151599)
                     /gene="yadK"
                     /locus_tag="b0136"
                     /gene_synonym="ECK0135; JW0132"
                     /db_xref="EcoGene:EG12325"
                     /db_xref="GeneID:944835"
     CDS             complement(151003..151599)
                     /gene="yadK"
                     /locus_tag="b0136"
                     /gene_synonym="ECK0135; JW0132"
                     /function="putative structural component; Surface
                     structures"
                     /note="putative fimbrial protein"
                     /codon_start=1
                     /transl_table=11
                     /product="putative fimbrial-like adhesin protein"
                     /protein_id="NP_414678.1"
                     /db_xref="GI:16128129"
                     /db_xref="ASAP:ABE-0000472"
                     /db_xref="UniProtKB/Swiss-Prot:P37016"
                     /db_xref="EcoGene:EG12325"
                     /db_xref="GeneID:944835"
                     /translation="MHPTQRKLMKRIILFLSLLFCIACPAIAGQDIDLVANVKNSTCK
                     SGISNQGNIDLGVVGVGYFSGNVTPESYQPGGKEFTITVSDCALQGTGDVLNQLHIDF
                     RALSGVMAAGSRQIFANEISSGASNVGVVIFSTQDSANTFNVLNASGGSRSVYPVMSD
                     DMNGSSWKFSTRMQKIDPALSVTSGQLMSHVLVDIYYE"
     misc_feature    complement(151006..151590)
                     /gene="yadK"
                     /locus_tag="b0136"
                     /gene_synonym="ECK0135; JW0132"
                     /note="putative fimbrial protein StaF; Provisional;
                     Region: PRK15262"
                     /db_xref="CDD:237933"
     gene            complement(151626..152231)
                     /gene="yadL"
                     /locus_tag="b0137"
                     /gene_synonym="ECK0136; JW0133"
                     /db_xref="EcoGene:EG12326"
                     /db_xref="GeneID:944829"
     CDS             complement(151626..152231)
                     /gene="yadL"
                     /locus_tag="b0137"
                     /gene_synonym="ECK0136; JW0133"
                     /function="putative structural component; Surface
                     structures"
                     /note="putative fimbrial protein"
                     /codon_start=1
                     /transl_table=11
                     /product="putative fimbrial-like adhesin protein"
                     /protein_id="NP_414679.1"
                     /db_xref="GI:16128130"
                     /db_xref="ASAP:ABE-0000475"
                     /db_xref="UniProtKB/Swiss-Prot:P37017"
                     /db_xref="EcoGene:EG12326"
                     /db_xref="GeneID:944829"
                     /translation="MMTFKNLRYGLSSSVVLAASLFSVLSYAATDSIGLTVITTVEMG
                     TCTATLVNDSDQDISVVDFGDVYISEINAKTKVKTFKLKFKDCAGIPNKKAQIKLTKR
                     ATCEGTANDGAGFANGSTAADKASAVAVEVWSTVTPATGSATQFSCVTPASQEVTIST
                     AANAVVYYPMSARLVVEKNKTVNNVTAGKFSAPATFTVTYN"
     misc_feature    complement(151629..152213)
                     /gene="yadL"
                     /locus_tag="b0137"
                     /gene_synonym="ECK0136; JW0133"
                     /note="putative fimbrial protein StaE; Provisional;
                     Region: PRK15263"
                     /db_xref="CDD:185171"
     gene            complement(152243..152812)
                     /gene="yadM"
                     /locus_tag="b0138"
                     /gene_synonym="ECK0137; JW0134"
                     /db_xref="EcoGene:EG12327"
                     /db_xref="GeneID:944828"
     CDS             complement(152243..152812)
                     /gene="yadM"
                     /locus_tag="b0138"
                     /gene_synonym="ECK0137; JW0134"
                     /function="putative structural component; Surface
                     structures"
                     /GO_component="GO:0009289 - pilus"
                     /note="putative fimbrial-like protein"
                     /codon_start=1
                     /transl_table=11
                     /product="putative fimbrial-like adhesin protein"
                     /protein_id="NP_414680.4"
                     /db_xref="GI:90111089"
                     /db_xref="ASAP:ABE-0000477"
                     /db_xref="UniProtKB/Swiss-Prot:P37018"
                     /db_xref="EcoGene:EG12327"
                     /db_xref="GeneID:944828"
                     /translation="MIKTTPHKIVILMGILLSPSVFATDINVEFTATVKATTCNITLT
                     GNNVTNDGNNNYTLRIPKMGLDKIANKTTESQADFKLVASGCSSGISWIDTTLTGNAS
                     SSSPKLIIPQSGDSSSTTSNIGMGFKKRTTDDATFLKPNSAEKIRWSTDEMQPDKGLE
                     MTVALRETDAGQGVPGNFRALATFNFIYQ"
     misc_feature    complement(152246..152746)
                     /gene="yadM"
                     /locus_tag="b0138"
                     /gene_synonym="ECK0137; JW0134"
                     /note="Fimbrial protein; Region: Fimbrial; cl01416"
                     /db_xref="CDD:260929"
     gene            complement(152829..155426)
                     /gene="htrE"
                     /locus_tag="b0139"
                     /gene_synonym="ECK0138; JW0135"
                     /db_xref="EcoGene:EG11972"
                     /db_xref="GeneID:944819"
     CDS             complement(152829..155426)
                     /gene="htrE"
                     /locus_tag="b0139"
                     /gene_synonym="ECK0138; JW0135"
                     /function="putative membrane; Surface structures"
                     /GO_component="GO:0009274 - peptidoglycan-based cell wall"
                     /GO_component="GO:0009279 - cell outer membrane"
                     /note="probable outer membrane porin protein involved in
                     fimbrial assembly"
                     /codon_start=1
                     /transl_table=11
                     /product="putative outer membrane usher protein"
                     /protein_id="NP_414681.1"
                     /db_xref="GI:16128132"
                     /db_xref="ASAP:ABE-0000479"
                     /db_xref="UniProtKB/Swiss-Prot:P33129"
                     /db_xref="EcoGene:EG11972"
                     /db_xref="GeneID:944819"
                     /translation="MTIEYTKNYHHLTRIATFCALLYCNTAFSAELVEYDHTFLMGQN
                     ASNIDLSRYSEGNPAIPGVYDVSVYVNDQPIINQSITFVAIEGKKNAQACITLKNLLQ
                     FHINSPDINNEKAVLLARDETLGNCLNLTEIIPQASVRYDVNDQRLDIDVPQAWVMKN
                     YQNYVDPSLWENGINAAMLSYNLNGYHSETPGRKNESIYAAFNGGMNLGAWRLRASGN
                     YNWMTDSGSNYDFKNRYVQRDIASLRSQLILGESYTTGETFDSVSIRGIRLYSDSRML
                     PPTLASFAPIIHGVANTNAKVTITQGGYKIYETTVPPGAFVIDDLSPSGYGSDLIVTI
                     EESDGSKRTFSQPFSSVVQMLRPGVGRWDISGGQVLKDDIQDEPNLFQASYYYGLNNY
                     LTGYTGIQITDNNYTAGLLGLGLNTSVGAFSFDVTHSNVRIPDDKTYQGQSYRVSWNK
                     LFEETSTSLNIAAYRYSTQNYLGLNDALTLIDEVKHPEQDLEPKSMRNYSRMKNQVTV
                     SINQPLKFEKKDYGSFYLSGSWSDYWASGQNRSNYSIGYSNSTSWGSYSVSAQRSWNE
                     DGDTDDSVYLSFTIPIEKLLGTEQRTSGFQSIDTQISSDFKGNNQLNVSSSGYSDNAR
                     VSYSVNTGYTMNKASKDLSYVGGYASYESPWGTLAGSISANSDNSRQVSLSTDGGFVL
                     HSGGLTFSNDSFSDSDTLAVVQAPGAQGARINYGNSTIDRWGYGVTSALSPYHENRIA
                     LDINDLENDVELKSTSAVAVPRQGSVVFADFETVQGQSAIMNITRSDGKNIPFAADIY
                     DEQGNVIGNVGQGGQAFVRGIEQQGNISIKWLEQSKPVSCLAHYQQSPEAEKIAQSII
                     LNGIRCQIQ"
     misc_feature    complement(152832..155426)
                     /gene="htrE"
                     /locus_tag="b0139"
                     /gene_synonym="ECK0138; JW0135"
                     /note="putative fimbrial outer membrane usher protein;
                     Provisional; Region: PRK09828"
                     /db_xref="CDD:182098"
     misc_feature    complement(154869..155330)
                     /gene="htrE"
                     /locus_tag="b0139"
                     /gene_synonym="ECK0138; JW0135"
                     /note="PapC N-terminal domain; Region: PapC_N; pfam13954"
                     /db_xref="CDD:258209"
     misc_feature    complement(153114..154832)
                     /gene="htrE"
                     /locus_tag="b0139"
                     /gene_synonym="ECK0138; JW0135"
                     /note="Outer membrane usher protein; Region: Usher;
                     pfam00577"
                     /db_xref="CDD:249973"
     misc_feature    complement(152880..153086)
                     /gene="htrE"
                     /locus_tag="b0139"
                     /gene_synonym="ECK0138; JW0135"
                     /note="PapC C-terminal domain; Region: PapC_C; pfam13953"
                     /db_xref="CDD:258208"
     gene            complement(155461..156201)
                     /gene="yadV"
                     /locus_tag="b0140"
                     /gene_synonym="ECK0139; ecpD; JW0136"
                     /db_xref="EcoGene:EG11973"
                     /db_xref="GeneID:944859"
     CDS             complement(155461..156201)
                     /gene="yadV"
                     /locus_tag="b0140"
                     /gene_synonym="ECK0139; ecpD; JW0136"
                     /function="putative factor; Surface structures"
                     /GO_component="GO:0019866 - organelle inner membrane"
                     /GO_process="GO:0006457 - protein folding"
                     /note="probable pilin chaperone similar to PapD"
                     /codon_start=1
                     /transl_table=11
                     /product="putative periplasmic pilin chaperone"
                     /protein_id="NP_414682.1"
                     /db_xref="GI:16128133"
                     /db_xref="ASAP:ABE-0000482"
                     /db_xref="UniProtKB/Swiss-Prot:P33128"
                     /db_xref="EcoGene:EG11973"
                     /db_xref="GeneID:944859"
                     /translation="MFFNTKHTTALCFVTCMAFSSSSIADIVISGTRVIYKSDQKSVN
                     VRLENKGNNPLLVQSWLDTGDDNAEPGSITVPFTATPPVSRIDAKRGQTIKLMYTAST
                     SLPKDRESVFWFNVLEVPPKPDAEKVANQSLLQLAFRTRIKLFYRPDGLKGNPSEAPL
                     ALKWFWSGSEGKASLRVTNPTPYYVSFSSGDLEASGKRYPIDVKMIAPFSDEVMKVNG
                     LNGKANSAKVHFYAINDFGGAIEGNARL"
     misc_feature    complement(155464..156201)
                     /gene="yadV"
                     /locus_tag="b0140"
                     /gene_synonym="ECK0139; ecpD; JW0136"
                     /note="putative chaperone protein EcpD; Provisional;
                     Region: PRK09926"
                     /db_xref="CDD:236634"
     misc_feature    complement(155746..156123)
                     /gene="yadV"
                     /locus_tag="b0140"
                     /gene_synonym="ECK0139; ecpD; JW0136"
                     /note="Pili and flagellar-assembly chaperone, PapD
                     N-terminal domain; Region: PapD_N; pfam00345"
                     /db_xref="CDD:249787"
     misc_feature    complement(155476..155679)
                     /gene="yadV"
                     /locus_tag="b0140"
                     /gene_synonym="ECK0139; ecpD; JW0136"
                     /note="Pili assembly chaperone PapD, C-terminal domain;
                     Region: PapD_C; pfam02753"
                     /db_xref="CDD:251514"
     gene            complement(156299..156883)
                     /gene="yadN"
                     /locus_tag="b0141"
                     /gene_synonym="ECK0140; JW0137"
                     /db_xref="EcoGene:EG12328"
                     /db_xref="GeneID:944841"
     CDS             complement(156299..156883)
                     /gene="yadN"
                     /locus_tag="b0141"
                     /gene_synonym="ECK0140; JW0137"
                     /function="putative structural component; Surface
                     structures"
                     /GO_component="GO:0009289 - pilus"
                     /note="putative fimbrial-like protein"
                     /codon_start=1
                     /transl_table=11
                     /product="putative fimbrial-like adhesin protein"
                     /protein_id="NP_414683.1"
                     /db_xref="GI:16128134"
                     /db_xref="ASAP:ABE-0000487"
                     /db_xref="UniProtKB/Swiss-Prot:P37050"
                     /db_xref="EcoGene:EG12328"
                     /db_xref="GeneID:944841"
                     /translation="MSKKLGFALSGLMLAMVAGTASADMDGGQLNISGLVVDNTCETR
                     VDGGNKDGLILLQTATVGEIDAGVLNDTVGAKAKPFSITVDCSKANPNPGSTAKMTFG
                     SVFFGNSKGTLNNDMSINNPSDGVNIALHNIDGSTIKQVQINNPGDVYTKALDATTKS
                     AVYDFKASYVRAVADQTATAGYVKTNTAYTITYQ"
     misc_feature    complement(156302..156859)
                     /gene="yadN"
                     /locus_tag="b0141"
                     /gene_synonym="ECK0140; JW0137"
                     /note="Fimbrial protein; Region: Fimbrial; cl01416"
                     /db_xref="CDD:260929"
     gene            complement(157253..157732)
                     /gene="folK"
                     /locus_tag="b0142"
                     /gene_synonym="ECK0141; JW0138"
                     /db_xref="EcoGene:EG11374"
                     /db_xref="GeneID:948792"
     CDS             complement(157253..157732)
                     /gene="folK"
                     /locus_tag="b0142"
                     /gene_synonym="ECK0141; JW0138"
                     /EC_number="2.7.6.3"
                     /function="enzyme; Biosynthesis of cofactors, carriers:
                     Folic acid"
                     /GO_process="GO:0046656 - folic acid biosynthetic process"
                     /note="7,8-dihydro-6-hydroxymethylpterin-
                     pyrophosphokinase"
                     /codon_start=1
                     /transl_table=11
                     /product="2-amino-4-hydroxy-6-hydroxymethyldihyropteridine
                     pyrophosphokinase"
                     /protein_id="NP_414684.1"
                     /db_xref="GI:16128135"
                     /db_xref="ASAP:ABE-0000491"
                     /db_xref="UniProtKB/Swiss-Prot:P26281"
                     /db_xref="EcoGene:EG11374"
                     /db_xref="GeneID:948792"
                     /translation="MTVAYIAIGSNLASPLEQVNAALKALGDIPESHILTVSSFYRTP
                     PLGPQDQPDYLNAAVALETSLAPEELLNHTQRIELQQGRVRKAERWGPRTLDLDIMLF
                     GNEVINTERLTVPHYDMKNRGFMLWPLFEIAPELVFPDGEMLRQILHTRAFDKLNKW"
     misc_feature    complement(157337..157723)
                     /gene="folK"
                     /locus_tag="b0142"
                     /gene_synonym="ECK0141; JW0138"
                     /note="7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase
                     (HPPK). Folate derivatives are essential cofactors in the
                     biosynthesis of purines, pyrimidines, and amino acids as
                     well as formyl-tRNA. Mammalian cells are able to utilize
                     pre-formed folates after...; Region: HPPK; cd00483"
                     /db_xref="CDD:238269"
     misc_feature    complement(order(157361..157363,157367..157369,
                     157382..157387,157394..157396,157436..157441,
                     157445..157447,157454..157456,157463..157465,
                     157478..157480,157484..157486,157499..157501,
                     157508..157510,157520..157522,157565..157567,
                     157571..157573,157595..157597,157601..157606,
                     157706..157708))
                     /gene="folK"
                     /locus_tag="b0142"
                     /gene_synonym="ECK0141; JW0138"
                     /note="catalytic center binding site [active]"
                     /db_xref="CDD:238269"
     misc_feature    complement(order(157367..157369,157382..157387,
                     157394..157396,157436..157441,157454..157456,
                     157478..157480,157484..157486,157499..157501,
                     157508..157510,157520..157522))
                     /gene="folK"
                     /locus_tag="b0142"
                     /gene_synonym="ECK0141; JW0138"
                     /note="ATP binding site [chemical binding]; other site"
                     /db_xref="CDD:238269"
     gene            complement(157729..159126)
                     /gene="pcnB"
                     /locus_tag="b0143"
                     /gene_synonym="ECK0142; JW5808"
                     /db_xref="EcoGene:EG10690"
                     /db_xref="GeneID:947318"
     CDS             complement(157729..159126)
                     /gene="pcnB"
                     /locus_tag="b0143"
                     /gene_synonym="ECK0142; JW5808"
                     /EC_number="2.7.7.19"
                     /function="enzyme; RNA synthesis, modification, DNA
                     transcription"
                     /GO_component="GO:0005737 - cytoplasm"
                     /GO_process="GO:0009451 - RNA modification"
                     /codon_start=1
                     /transl_table=11
                     /product="poly(A) polymerase"
                     /protein_id="NP_414685.4"
                     /db_xref="GI:162135892"
                     /db_xref="ASAP:ABE-0000493"
                     /db_xref="UniProtKB/Swiss-Prot:P0ABF1"
                     /db_xref="EcoGene:EG10690"
                     /db_xref="GeneID:947318"
                     /translation="MFTRVANFCRKVLSREESEAEQAVARPQVTVIPREQHAISRKDI
                     SENALKVMYRLNKAGYEAWLVGGGVRDLLLGKKPKDFDVTTNATPEQVRKLFRNCRLV
                     GRRFRLAHVMFGPEIIEVATFRGHHEGNVSDRTTSQRGQNGMLLRDNIFGSIEEDAQR
                     RDFTINSLYYSVADFTVRDYVGGMKDLKDGVIRLIGNPETRYREDPVRMLRAVRFAAK
                     LGMRISPETAEPIPRLATLLNDIPPARLFEESLKLLQAGYGYETYKLLCEYHLFQPLF
                     PTITRYFTENGDSPMERIIEQVLKNTDTRIHNDMRVNPAFLFAAMFWYPLLETAQKIA
                     QESGLTYHDAFALAMNDVLDEACRSLAIPKRLTTLTRDIWQLQLRMSRRQGKRAWKLL
                     EHPKFRAAYDLLALRAEVERNAELQRLVKWWGEFQVSAPPDQKGMLNELDEEPSPRRR
                     TRRPRKRAPRREGTA"
     misc_feature    complement(157795..159126)
                     /gene="pcnB"
                     /locus_tag="b0143"
                     /gene_synonym="ECK0142; JW5808"
                     /note="poly(A) polymerase I; Provisional; Region: pcnB;
                     PRK11623"
                     /db_xref="CDD:236939"
     misc_feature    complement(158560..158994)
                     /gene="pcnB"
                     /locus_tag="b0143"
                     /gene_synonym="ECK0142; JW5808"
                     /note="Nucleotidyltransferase (NT) domain of ClassII
                     CCA-adding enzymes; Region: NT_ClassII-CCAase; cd05398"
                     /db_xref="CDD:143388"
     misc_feature    complement(order(158629..158631,158638..158649,
                     158755..158757,158770..158772,158809..158811,
                     158881..158883,158887..158889,158914..158919,
                     158926..158931))
                     /gene="pcnB"
                     /locus_tag="b0143"
                     /gene_synonym="ECK0142; JW5808"
                     /note="active site"
                     /db_xref="CDD:143388"
     misc_feature    complement(order(158629..158631,158641..158649,
                     158881..158883,158887..158889,158917..158919,
                     158926..158931))
                     /gene="pcnB"
                     /locus_tag="b0143"
                     /gene_synonym="ECK0142; JW5808"
                     /note="NTP binding site [chemical binding]; other site"
                     /db_xref="CDD:143388"
     misc_feature    complement(order(158770..158772,158881..158883,
                     158887..158889))
                     /gene="pcnB"
                     /locus_tag="b0143"
                     /gene_synonym="ECK0142; JW5808"
                     /note="metal binding triad [ion binding]; metal-binding
                     site"
                     /db_xref="CDD:143388"
     misc_feature    complement(158278..158469)
                     /gene="pcnB"
                     /locus_tag="b0143"
                     /gene_synonym="ECK0142; JW5808"
                     /note="Probable RNA and SrmB- binding site of polymerase
                     A; Region: PolyA_pol_RNAbd; pfam12627"
                     /db_xref="CDD:257174"
     misc_feature    complement(157795..158124)
                     /gene="pcnB"
                     /locus_tag="b0143"
                     /gene_synonym="ECK0142; JW5808"
                     /note="Polymerase A arginine-rich C-terminus; Region:
                     PolyA_pol_arg_C; pfam12626"
                     /db_xref="CDD:257173"
     gene            complement(159186..160112)
                     /gene="gluQ"
                     /locus_tag="b0144"
                     /gene_synonym="ECK0143; JW5892; yadB"
                     /db_xref="EcoGene:EG11362"
                     /db_xref="GeneID:944846"
     CDS             complement(159186..160112)
                     /gene="gluQ"
                     /locus_tag="b0144"
                     /gene_synonym="ECK0143; JW5892; yadB"
                     /EC_number="6.1.1.-"
                     /function="putative enzyme; Aminoacyl tRNA synthetases,
                     tRNA modification"
                     /GO_process="GO:0006418 - tRNA aminoacylation for protein
                     translation"
                     /note="putative tRNA synthetase"
                     /codon_start=1
                     /transl_table=11
                     /product="glutamyl-Q tRNA(Asp) synthetase"
                     /protein_id="NP_414686.3"
                     /db_xref="GI:226524698"
                     /db_xref="ASAP:ABE-0000497"
                     /db_xref="UniProtKB/Swiss-Prot:P27305"
                     /db_xref="EcoGene:EG11362"
                     /db_xref="GeneID:944846"
                     /translation="MLPPYFLFKEMTDTQYIGRFAPSPSGELHFGSLIAALGSYLQAR
                     ARQGRWLVRIEDIDPPREVPGAAETILRQLEHYGLHWDGDVLWQSQRHDAYREALAWL
                     HEQGLSYYCTCTRARIQSIGGIYDGHCRVLHHGPDNAAVRIRQQHPVTQFTDQLRGII
                     HADEKLAREDFIIHRRDGLFAYNLAVVVDDHFQGVTEIVRGADLIEPTVRQISLYQLF
                     GWKVPDYIHLPLALNPQGAKLSKQNHAPALPKGDPRPVLIAALQFLGQQAEAHWQDFS
                     VEQILQSAVKNWRLTAVPESAIVNSTFSNASC"
     misc_feature    complement(159204..160082)
                     /gene="gluQ"
                     /locus_tag="b0144"
                     /gene_synonym="ECK0143; JW5892; yadB"
                     /note="glutamyl-Q tRNA(Asp) synthetase; Reviewed; Region:
                     PRK05710"
                     /db_xref="CDD:235573"
     misc_feature    complement(159264..160058)
                     /gene="gluQ"
                     /locus_tag="b0144"
                     /gene_synonym="ECK0143; JW5892; yadB"
                     /note="tRNA synthetases class I (E and Q), catalytic
                     domain; Region: tRNA-synt_1c; pfam00749"
                     /db_xref="CDD:250104"
     misc_feature    complement(order(159390..159395,160017..160028))
                     /gene="gluQ"
                     /locus_tag="b0144"
                     /gene_synonym="ECK0143; JW5892; yadB"
                     /note="active site"
                     /db_xref="CDD:173912"
     misc_feature    complement(order(159390..159392,160017..160019,
                     160026..160028))
                     /gene="gluQ"
                     /locus_tag="b0144"
                     /gene_synonym="ECK0143; JW5892; yadB"
                     /note="nucleotide binding site [chemical binding]; other
                     site"
                     /db_xref="CDD:173912"
     misc_feature    complement(160017..160028)
                     /gene="gluQ"
                     /locus_tag="b0144"
                     /gene_synonym="ECK0143; JW5892; yadB"
                     /note="HIGH motif; other site"
                     /db_xref="CDD:173912"
     misc_feature    complement(159390..159395)
                     /gene="gluQ"
                     /locus_tag="b0144"
                     /gene_synonym="ECK0143; JW5892; yadB"
                     /note="KMSKS motif; other site"
                     /db_xref="CDD:173912"
     gene            complement(160149..160604)
                     /gene="dksA"
                     /locus_tag="b0145"
                     /gene_synonym="ECK0144; JW0141; msmA"
                     /db_xref="EcoGene:EG10230"
                     /db_xref="GeneID:944850"
     CDS             complement(160149..160604)
                     /gene="dksA"
                     /locus_tag="b0145"
                     /gene_synonym="ECK0144; JW0141; msmA"
                     /function="phenotype; DNA - replication, repair,
                     restriction/modification"
                     /experiment="N-terminus verified by Edman degradation:
                     PMID 9298646,9600841,9740056"
                     /GO_component="GO:0005737 - cytoplasm"
                     /GO_process="GO:0006457 - protein folding"
                     /note="dnaK suppressor protein"
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator of rRNA transcription;
                     DnaK suppressor protein"
                     /protein_id="NP_414687.1"
                     /db_xref="GI:16128138"
                     /db_xref="ASAP:ABE-0000499"
                     /db_xref="UniProtKB/Swiss-Prot:P0ABS1"
                     /db_xref="EcoGene:EG10230"
                     /db_xref="GeneID:944850"
                     /translation="MQEGQNRKTSSLSILAIAGVEPYQEKPGEEYMNEAQLAHFRRIL
                     EAWRNQLRDEVDRTVTHMQDEAANFPDPVDRAAQEEEFSLELRNRDRERKLIKKIEKT
                     LKKVEDEDFGYCESCGVEIGIRRLEARPTADLCIDCKTLAEIREKQMAG"
     misc_feature    complement(160152..160604)
                     /gene="dksA"
                     /locus_tag="b0145"
                     /gene_synonym="ECK0144; JW0141; msmA"
                     /note="RNA polymerase-binding transcription factor;
                     Provisional; Region: dksA; PRK10778"
                     /db_xref="CDD:182722"
     gene            complement(160782..161486)
                     /gene="sfsA"
                     /locus_tag="b0146"
                     /gene_synonym="ECK0145; JW0142; sfs; sfs1"
                     /db_xref="EcoGene:EG10949"
                     /db_xref="GeneID:944855"
     CDS             complement(160782..161486)
                     /gene="sfsA"
                     /locus_tag="b0146"
                     /gene_synonym="ECK0145; JW0142; sfs; sfs1"
                     /function="putative regulator; Degradation of small
                     molecules: Carbon compounds"
                     /GO_process="GO:0016052 - carbohydrate catabolic process"
                     /note="probable regulator for maltose metabolism"
                     /codon_start=1
                     /transl_table=11
                     /product="sugar fermentation stimulation protein A"
                     /protein_id="NP_414688.1"
                     /db_xref="GI:16128139"
                     /db_xref="ASAP:ABE-0000503"
                     /db_xref="UniProtKB/Swiss-Prot:P0A823"
                     /db_xref="EcoGene:EG10949"
                     /db_xref="GeneID:944855"
                     /translation="MEFSPPLQRATLIQRYKRFLADVITPDGRELTLHCPNTGAMTGC
                     ATPGDTVWYSTSDNTKRKYPHTWELTQSQSGAFICVNTLWANRLTKEAILNESISELS
                     GYSSLKSEVKYGAERSRIDFMLQADSRPDCYIEVKSVTLAENEQGYFPDAVTERGQKH
                     LRELMSVAAEGQRAVIFFAVLHSAITRFSPARHIDEKYAQLLSEAQQRGVEILAYKAE
                     ISAEGMALKKSLPVTL"
     misc_feature    complement(160785..161486)
                     /gene="sfsA"
                     /locus_tag="b0146"
                     /gene_synonym="ECK0145; JW0142; sfs; sfs1"
                     /note="putative DNA-binding transcriptional regulator;
                     Reviewed; Region: PRK00347"
                     /db_xref="CDD:234733"
     gene            complement(161501..162031)
                     /gene="ligT"
                     /locus_tag="b0147"
                     /gene_synonym="ECK0146; JW5011; yadP"
                     /db_xref="EcoGene:EG12330"
                     /db_xref="GeneID:944848"
     CDS             complement(161501..162031)
                     /gene="ligT"
                     /locus_tag="b0147"
                     /gene_synonym="ECK0146; JW5011; yadP"
                     /EC_number="6.5.1.-"
                     /function="enzyme; tRNA modification"
                     /GO_component="GO:0005737 - cytoplasm"
                     /GO_process="GO:0009451 - RNA modification"
                     /codon_start=1
                     /transl_table=11
                     /product="2'-5' RNA ligase"
                     /protein_id="NP_414689.4"
                     /db_xref="GI:90111091"
                     /db_xref="ASAP:ABE-0000505"
                     /db_xref="UniProtKB/Swiss-Prot:P37025"
                     /db_xref="EcoGene:EG12330"
                     /db_xref="GeneID:944848"
                     /translation="MSEPQRLFFAIDLPAEIREQIIHWRATHFPPEAGRPVAADNLHL
                     TLAFLGEVSAEKEKALSLLAGRIRQPGFTLTLDDAGQWLRSRVVWLGMRQPPRGLIQL
                     ANMLRSQAARSGCFQSNRPFHPHITLLRDASEAVTIPPPGFNWSYAVTEFTLYASSFA
                     RGRTRYTPLKRWALTQ"
     misc_feature    complement(161504..162031)
                     /gene="ligT"
                     /locus_tag="b0147"
                     /gene_synonym="ECK0146; JW5011; yadP"
                     /note="2'-5' RNA ligase; Provisional; Region: PRK15124"
                     /db_xref="CDD:185079"
     misc_feature    complement(161765..162001)
                     /gene="ligT"
                     /locus_tag="b0147"
                     /gene_synonym="ECK0146; JW5011; yadP"
                     /note="LigT like Phosphoesterase; Region: LigT_PEase;
                     pfam02834"
                     /db_xref="CDD:251562"
     misc_feature    complement(161534..161758)
                     /gene="ligT"
                     /locus_tag="b0147"
                     /gene_synonym="ECK0146; JW5011; yadP"
                     /note="LigT like Phosphoesterase; Region: LigT_PEase;
                     pfam02834"
                     /db_xref="CDD:251562"
     gene            162105..164534
                     /gene="hrpB"
                     /locus_tag="b0148"
                     /gene_synonym="ECK0147; JW0144; yadO"
                     /db_xref="EcoGene:EG12329"
                     /db_xref="GeneID:944845"
     CDS             162105..164534
                     /gene="hrpB"
                     /locus_tag="b0148"
                     /gene_synonym="ECK0147; JW0144; yadO"
                     /function="enzyme; DNA - replication, repair,
                     restriction/modification"
                     /GO_component="GO:0005737 - cytoplasm"
                     /GO_process="GO:0006261 - DNA-dependent DNA replication"
                     /note="helicase, ATP-dependent"
                     /codon_start=1
                     /transl_table=11
                     /product="putative ATP-dependent helicase"
                     /protein_id="NP_414690.4"
                     /db_xref="GI:162135893"
                     /db_xref="ASAP:ABE-0000510"
                     /db_xref="UniProtKB/Swiss-Prot:P37024"
                     /db_xref="EcoGene:EG12329"
                     /db_xref="GeneID:944845"
                     /translation="MSSLPVAAVLPELLTALDCAPQVLLSAPTGAGKSTWLPLQLLAH
                     PGINGKIILLEPRRLAARNVAQRLAELLNEKPGDTVGYRMRAQNCVGPNTRLEVVTEG
                     VLTRMIQRDPELSGVGLVILDEFHERSLQADLALALLLDVQQGLRDDLKLLIMSATLD
                     NDRLQQMLPEAPVVISEGRSFPVERRYLPLPAHQRFDDAVAVATAEMLRQESGSLLLF
                     LPGVGEIQRVQEQLASRIGSDVLLCPLYGALSLNDQRKAILPAPQGMRKVVLATNIAE
                     TSLTIEGIRLVVDCAQERVARFDPRTGLTRLITQRVSQASMTQRAGRAGRLEPGISLH
                     LIAKEQAERAAAQSEPEILQSDLSGLLMELLQWGCSDPAQMSWLDQPPVVNLLAAKRL
                     LQMLGALEGERLSAQGQKMAALGNDPRLAAMLVSAKNDDEAATAAKIAAILEEPPRMG
                     NSDLGVAFSRNQPAWQQRSQQLLKRLNVRGGEADSSLIAPLLAGAFADRIARRRGQDG
                     RYQLANGMGAMLDANDALSRHEWLIAPLLLQGSASPDARILLALLVDIDELVQRCPQL
                     VQQSDTVEWDDAQGTLKAWRRLQIGQLTVKVQPLAKPSEDELHQAMLNGIRDKGLSVL
                     NWTAEAEQLRLRLLCAAKWLPEYDWPAVDDESLLAALETWLLPHMTGVHSLRGLKSLD
                     IYQALRGLLDWGMQQRLDSELPAHYTVPTGSRIAIRYHEDNPPALAVRMQEMFGEATN
                     PTIAQGRVPLVLELLSPAQRPLQITRDLSDFWKGAYREVQKEMKGRYPKHVWPDDPAN
                     TAPTRRTKKYS"
     misc_feature    162105..164531
                     /gene="hrpB"
                     /locus_tag="b0148"
                     /gene_synonym="ECK0147; JW0144; yadO"
                     /note="ATP-dependent RNA helicase HrpB; Provisional;
                     Region: PRK11664"
                     /db_xref="CDD:236950"
     misc_feature    162171..162581
                     /gene="hrpB"
                     /locus_tag="b0148"
                     /gene_synonym="ECK0147; JW0144; yadO"
                     /note="DEAD-like helicases superfamily. A diverse family
                     of proteins involved in ATP-dependent RNA or DNA
                     unwinding. This domain contains the ATP-binding region;
                     Region: DEXDc; cd00046"
                     /db_xref="CDD:238005"
     misc_feature    162192..162206
                     /gene="hrpB"
                     /locus_tag="b0148"
                     /gene_synonym="ECK0147; JW0144; yadO"
                     /note="ATP binding site [chemical binding]; other site"
                     /db_xref="CDD:238005"
     misc_feature    162471..162482
                     /gene="hrpB"
                     /locus_tag="b0148"
                     /gene_synonym="ECK0147; JW0144; yadO"
                     /note="putative Mg++ binding site [ion binding]; other
                     site"
                     /db_xref="CDD:238005"
     misc_feature    162720..163109
                     /gene="hrpB"
                     /locus_tag="b0148"
                     /gene_synonym="ECK0147; JW0144; yadO"
                     /note="Helicase superfamily c-terminal domain; associated
                     with DEXDc-, DEAD-, and DEAH-box proteins, yeast
                     initiation factor 4A, Ski2p, and Hepatitis C virus NS3
                     helicases; this domain is found in a wide variety of
                     helicases and helicase related proteins; may...; Region:
                     HELICc; cd00079"
                     /db_xref="CDD:238034"
     misc_feature    order(162762..162773,162840..162845,162918..162926)
                     /gene="hrpB"
                     /locus_tag="b0148"
                     /gene_synonym="ECK0147; JW0144; yadO"
                     /note="nucleotide binding region [chemical binding]; other
                     site"
                     /db_xref="CDD:238034"
     misc_feature    order(162942..162944,163059..163061,163071..163073,
                     163080..163082)
                     /gene="hrpB"
                     /locus_tag="b0148"
                     /gene_synonym="ECK0147; JW0144; yadO"
                     /note="ATP-binding site [chemical binding]; other site"
                     /db_xref="CDD:238034"
     misc_feature    163287..>163388
                     /gene="hrpB"
                     /locus_tag="b0148"
                     /gene_synonym="ECK0147; JW0144; yadO"
                     /note="Helicase associated domain (HA2) Add an annotation;
                     Region: HA2; smart00847"
                     /db_xref="CDD:214852"
     misc_feature    164094..164492
                     /gene="hrpB"
                     /locus_tag="b0148"
                     /gene_synonym="ECK0147; JW0144; yadO"
                     /note="ATP-dependent helicase C-terminal; Region: HrpB_C;
                     pfam08482"
                     /db_xref="CDD:254823"
     gene            164730..167264
                     /gene="mrcB"
                     /locus_tag="b0149"
                     /gene_synonym="ECK0148; JW0145; pbpF; ponB"
                     /db_xref="EcoGene:EG10605"
                     /db_xref="GeneID:944843"
     CDS             164730..167264
                     /gene="mrcB"
                     /locus_tag="b0149"
                     /gene_synonym="ECK0148; JW0145; pbpF; ponB"
                     /EC_number="2.4.1.129"
                     /EC_number="3.4.-.-"
                     /function="enzyme; Murein sacculus, peptidoglycan"
                     /GO_component="GO:0009274 - peptidoglycan-based cell wall"
                     /GO_component="GO:0019866 - organelle inner membrane"
                     /GO_process="GO:0046349 - amino sugar biosynthetic
                     process"
                     /GO_process="GO:0009252 - peptidoglycan biosynthetic
                     process"
                     /GO_process="GO:0042493 - response to drug"
                     /note="peptidoglycan synthetase; penicillin-binding
                     protein 1B"
                     /codon_start=1
                     /transl_table=11
                     /product="fused glycosyl transferase and transpeptidase"
                     /protein_id="NP_414691.1"
                     /db_xref="GI:16128142"
                     /db_xref="ASAP:ABE-0000516"
                     /db_xref="UniProtKB/Swiss-Prot:P02919"
                     /db_xref="EcoGene:EG10605"
                     /db_xref="GeneID:944843"
                     /translation="MAGNDREPIGRKGKPTRPVKQKVSRRRYEDDDDYDDYDDYEDEE
                     PMPRKGKGKGKGRKPRGKRGWLWLLLKLAIVFAVLIAIYGVYLDQKIRSRIDGKVWQL
                     PAAVYGRMVNLEPDMTISKNEMVKLLEATQYRQVSKMTRPGEFTVQANSIEMIRRPFD
                     FPDSKEGQVRARLTFDGDHLATIVNMENNRQFGFFRLDPRLITMISSPNGEQRLFVPR
                     SGFPDLLVDTLLATEDRHFYEHDGISLYSIGRAVLANLTAGRTVQGASTLTQQLVKNL
                     FLSSERSYWRKANEAYMALIMDARYSKDRILELYMNEVYLGQSGDNEIRGFPLASLYY
                     FGRPVEELSLDQQALLVGMVKGASIYNPWRNPKLALERRNLVLRLLQQQQIIDQELYD
                     MLSARPLGVQPRGGVISPQPAFMQLVRQELQAKLGDKVKDLSGVKIFTTFDSVAQDAA
                     EKAAVEGIPALKKQRKLSDLETAIVVVDRFSGEVRAMVGGSEPQFAGYNRAMQARRSI
                     GSLAKPATYLTALSQPKIYRLNTWIADAPIALRQPNGQVWSPQNDDRRYSESGRVMLV
                     DALTRSMNVPTVNLGMALGLPAVTETWIKLGVPKDQLHPVPAMLLGALNLTPIEVAQA
                     FQTIASGGNRAPLSALRSVIAEDGKVLYQSFPQAERAVPAQAAYLTLWTMQQVVQRGT
                     GRQLGAKYPNLHLAGKTGTTNNNVDTWFAGIDGSTVTITWVGRDNNQPTKLYGASGAM
                     SIYQRYLANQTPTPLNLVPPEDIADMGVDYDGNFVCSGGMRILPVWTSDPQSLCQQSE
                     MQQQPSGNPFDQSSQPQQQPQQQPAQQEQKDSDGVAGWIKDMFGSN"
     misc_feature    164730..167258
                     /gene="mrcB"
                     /locus_tag="b0149"
                     /gene_synonym="ECK0148; JW0145; pbpF; ponB"
                     /note="bifunctional glycosyl transferase/transpeptidase;
                     Reviewed; Region: mrcB; PRK09506"
                     /db_xref="CDD:236544"
     misc_feature    164730..164966
                     /gene="mrcB"
                     /locus_tag="b0149"
                     /gene_synonym="ECK0148; JW0145; pbpF; ponB"
                     /note="Transmembrane domain of transglycosylase PBP1 at
                     N-terminal; Region: PBP1_TM; pfam14812"
                     /db_xref="CDD:258949"
     misc_feature    165066..165320
                     /gene="mrcB"
                     /locus_tag="b0149"
                     /gene_synonym="ECK0148; JW0145; pbpF; ponB"
                     /note="Bifunctional transglycosylase second domain;
                     Region: UB2H; pfam14814"
                     /db_xref="CDD:258951"
     misc_feature    165336..165851
                     /gene="mrcB"
                     /locus_tag="b0149"
                     /gene_synonym="ECK0148; JW0145; pbpF; ponB"
                     /note="Transglycosylase; Region: Transgly; pfam00912"
                     /db_xref="CDD:250219"
     misc_feature    166146..166871
                     /gene="mrcB"
                     /locus_tag="b0149"
                     /gene_synonym="ECK0148; JW0145; pbpF; ponB"
                     /note="Penicillin binding protein transpeptidase domain;
                     Region: Transpeptidase; cl17760"
                     /db_xref="CDD:266819"
     repeat_region   167281..167305
                     /note="REP12 (repetitive extragenic palindromic) element;
                     contains 1 REP sequences"
     gene            167484..169727
                     /gene="fhuA"
                     /locus_tag="b0150"
                     /gene_synonym="ECK0149; JW0146; T1; tonA"
                     /db_xref="EcoGene:EG10302"
                     /db_xref="GeneID:944856"
     CDS             167484..169727
                     /gene="fhuA"
                     /locus_tag="b0150"
                     /gene_synonym="ECK0149; JW0146; T1; tonA"
                     /function="membrane; Outer membrane constituents"
                     /GO_component="GO:0009274 - peptidoglycan-based cell wall"
                     /GO_component="GO:0009279 - cell outer membrane"
                     /note="outer membrane protein receptor for ferrichrome,
                     colicin M, and phages T1, T5, and phi80"
                     /codon_start=1
                     /transl_table=11
                     /product="ferrichrome outer membrane transporter"
                     /protein_id="NP_414692.1"
                     /db_xref="GI:16128143"
                     /db_xref="ASAP:ABE-0000520"
                     /db_xref="UniProtKB/Swiss-Prot:P06971"
                     /db_xref="EcoGene:EG10302"
                     /db_xref="GeneID:944856"
                     /translation="MARSKTAQPKHSLRKIAVVVATAVSGMSVYAQAAVEPKEDTITV
                     TAAPAPQESAWGPAATIAARQSATGTKTDTPIQKVPQSISVVTAEEMALHQPKSVKEA
                     LSYTPGVSVGTRGASNTYDHLIIRGFAAEGQSQNNYLNGLKLQGNFYNDAVIDPYMLE
                     RAEIMRGPVSVLYGKSSPGGLLNMVSKRPTTEPLKEVQFKAGTDSLFQTGFDFSDSLD
                     DDGVYSYRLTGLARSANAQQKGSEEQRYAIAPAFTWRPDDKTNFTFLSYFQNEPETGY
                     YGWLPKEGTVEPLPNGKRLPTDFNEGAKNNTYSRNEKMVGYSFDHEFNDTFTVRQNLR
                     FAENKTSQNSVYGYGVCSDPANAYSKQCAALAPADKGHYLARKYVVDDEKLQNFSVDT
                     QLQSKFATGDIDHTLLTGVDFMRMRNDINAWFGYDDSVPLLNLYNPVNTDFDFNAKDP
                     ANSGPYRILNKQKQTGVYVQDQAQWDKVLVTLGGRYDWADQESLNRVAGTTDKRDDKQ
                     FTWRGGVNYLFDNGVTPYFSYSESFEPSSQVGKDGNIFAPSKGKQYEVGVKYVPEDRP
                     IVVTGAVYNLTKTNNLMADPEGSFFSVEGGEIRARGVEIEAKAALSASVNVVGSYTYT
                     DAEYTTDTTYKGNTPAQVPKHMASLWADYTFFDGPLSGLTLGTGGRYTGSSYGDPANS
                     FKVGSYTVVDALVRYDLARVGMAGSNVALHVNNLFDREYVASCFNTYGCFWGAERQVV
                     ATATFRF"
     misc_feature    167484..169724
                     /gene="fhuA"
                     /locus_tag="b0150"
                     /gene_synonym="ECK0149; JW0146; T1; tonA"
                     /note="ferrichrome outer membrane transporter;
                     Provisional; Region: PRK10044"
                     /db_xref="CDD:236643"
     misc_feature    167727..169724
                     /gene="fhuA"
                     /locus_tag="b0150"
                     /gene_synonym="ECK0149; JW0146; T1; tonA"
                     /note="TonB dependent/Ligand-Gated channels are created by
                     a monomeric 22 strand (22,24) anti-parallel beta-barrel.
                     Ligands apparently bind to the large extracellular loops.
                     The N-terminal 150-200 residues form a plug from the
                     periplasmic end of barrel; Region: ligand_gated_channel;
                     cd01347"
                     /db_xref="CDD:238657"
     misc_feature    order(167727..167756,167784..167813,167850..167867,
                     167886..167888,167895..167915,167949..167981,
                     168015..168041)
                     /gene="fhuA"
                     /locus_tag="b0150"
                     /gene_synonym="ECK0149; JW0146; T1; tonA"
                     /note="N-terminal plug; other site"
                     /db_xref="CDD:238657"
     misc_feature    order(168501..168503,168630..168632)
                     /gene="fhuA"
                     /locus_tag="b0150"
                     /gene_synonym="ECK0149; JW0146; T1; tonA"
                     /note="ligand-binding site [chemical binding]; other site"
                     /db_xref="CDD:238657"
     gene            169778..170575
                     /gene="fhuC"
                     /locus_tag="b0151"
                     /gene_synonym="ECK0150; JW0147"
                     /db_xref="EcoGene:EG10304"
                     /db_xref="GeneID:945250"
     CDS             169778..170575
                     /gene="fhuC"
                     /locus_tag="b0151"
                     /gene_synonym="ECK0150; JW0147"
                     /function="transport; Transport of small molecules:
                     Cations"
                     /GO_component="GO:0005737 - cytoplasm"
                     /note="ATP-binding component of hydroxymate-dependent iron
                     transport"
                     /codon_start=1
                     /transl_table=11
                     /product="iron(3+)-hydroxamate import ABC transporter
                     ATPase"
                     /protein_id="NP_414693.1"
                     /db_xref="GI:16128144"
                     /db_xref="ASAP:ABE-0000522"
                     /db_xref="UniProtKB/Swiss-Prot:P07821"
                     /db_xref="EcoGene:EG10304"
                     /db_xref="GeneID:945250"
                     /translation="MQEYTNHSDTTFALRNISFRVPGRTLLHPLSLTFPAGKVTGLIG
                     HNGSGKSTLLKMLGRHQPPSEGEILLDAQPLESWSSKAFARKVAYLPQQLPPAEGMTV
                     RELVAIGRYPWHGALGRFGAADREKVEEAISLVGLKPLAHRLVDSLSGGERQRAWIAM
                     LVAQDSRCLLLDEPTSALDIAHQVDVLSLVHRLSQERGLTVIAVLHDINMAARYCDYL
                     VALRGGEMIAQGTPAEIMRGETLEMIYGIPMGILPHPAGAAPVSFVY"
     misc_feature    169778..170572
                     /gene="fhuC"
                     /locus_tag="b0151"
                     /gene_synonym="ECK0150; JW0147"
                     /note="iron-hydroxamate transporter ATP-binding subunit;
                     Provisional; Region: PRK10575"
                     /db_xref="CDD:182561"
     misc_feature    169814..170467
                     /gene="fhuC"
                     /locus_tag="b0151"
                     /gene_synonym="ECK0150; JW0147"
                     /note="ATP-binding component of iron-siderophores, vitamin
                     B12 and hemin transporters and related proteins; Region:
                     ABC_Iron-Siderophores_B12_Hemin; cd03214"
                     /db_xref="CDD:213181"
     misc_feature    169907..169930
                     /gene="fhuC"
                     /locus_tag="b0151"
                     /gene_synonym="ECK0150; JW0147"
                     /note="Walker A/P-loop; other site"
                     /db_xref="CDD:213181"
     misc_feature    order(169916..169921,169925..169933,170051..170053,
                     170291..170296,170393..170395)
                     /gene="fhuC"
                     /locus_tag="b0151"
                     /gene_synonym="ECK0150; JW0147"
                     /note="ATP binding site [chemical binding]; other site"
                     /db_xref="CDD:213181"
     misc_feature    170042..170053
                     /gene="fhuC"
                     /locus_tag="b0151"
                     /gene_synonym="ECK0150; JW0147"
                     /note="Q-loop/lid; other site"
                     /db_xref="CDD:213181"
     misc_feature    170219..170248
                     /gene="fhuC"
                     /locus_tag="b0151"
                     /gene_synonym="ECK0150; JW0147"
                     /note="ABC transporter signature motif; other site"
                     /db_xref="CDD:213181"
     misc_feature    170279..170296
                     /gene="fhuC"
                     /locus_tag="b0151"
                     /gene_synonym="ECK0150; JW0147"
                     /note="Walker B; other site"
                     /db_xref="CDD:213181"
     misc_feature    170303..170314
                     /gene="fhuC"
                     /locus_tag="b0151"
                     /gene_synonym="ECK0150; JW0147"
                     /note="D-loop; other site"
                     /db_xref="CDD:213181"
     misc_feature    170381..170401
                     /gene="fhuC"
                     /locus_tag="b0151"
                     /gene_synonym="ECK0150; JW0147"
                     /note="H-loop/switch region; other site"
                     /db_xref="CDD:213181"
     gene            170575..171465
                     /gene="fhuD"
                     /locus_tag="b0152"
                     /gene_synonym="ECK0151; JW0148"
                     /db_xref="EcoGene:EG10305"
                     /db_xref="GeneID:947510"
     CDS             170575..171465
                     /gene="fhuD"
                     /locus_tag="b0152"
                     /gene_synonym="ECK0151; JW0148"
                     /function="transport; Transport of small molecules:
                     Cations"
                     /GO_component="GO:0042597 - periplasmic space"
                     /GO_process="GO:0006826 - iron ion transport"
                     /note="hydroxamate-dependent iron uptake, cytoplasmic
                     membrane component; periplasmic-binding component of ABC
                     superfamily"
                     /codon_start=1
                     /transl_table=11
                     /product="iron(3+)-hydroxamate import ABC transporter
                     periplasmic binding protein"
                     /protein_id="NP_414694.1"
                     /db_xref="GI:16128145"
                     /db_xref="ASAP:ABE-0000524"
                     /db_xref="UniProtKB/Swiss-Prot:P07822"
                     /db_xref="EcoGene:EG10305"
                     /db_xref="GeneID:947510"
                     /translation="MSGLPLISRRRLLTAMALSPLLWQMNTAHAAAIDPNRIVALEWL
                     PVELLLALGIVPYGVADTINYRLWVSEPPLPDSVIDVGLRTEPNLELLTEMKPSFMVW
                     SAGYGPSPEMLARIAPGRGFNFSDGKQPLAMARKSLTEMADLLNLQSAAETHLAQYED
                     FIRSMKPRFVKRGARPLLLTTLIDPRHMLVFGPNSLFQEILDEYGIPNAWQGETNFWG
                     STAVSIDRLAAYKDVDVLCFDHDNSKDMDALMATPLWQAMPFVRAGRFQRVPAVWFYG
                     ATLSAMHFVRVLDNAIGGKA"
     misc_feature    170674..171429
                     /gene="fhuD"
                     /locus_tag="b0152"
                     /gene_synonym="ECK0151; JW0148"
                     /note="Fe3+-siderophore binding domain FhuD.  These
                     proteins have been shown to function as initial receptors
                     in ABC transport of Fe3+-siderophores in many eubacterial
                     species. They belong to the TroA-like superfamily of
                     helical backbone metal receptor proteins...; Region: FhuD;
                     cd01146"
                     /db_xref="CDD:238566"
     misc_feature    170686..171393
                     /gene="fhuD"
                     /locus_tag="b0152"
                     /gene_synonym="ECK0151; JW0148"
                     /note="Periplasmic binding protein; Region: Peripla_BP_2;
                     pfam01497"
                     /db_xref="CDD:250662"
     misc_feature    order(170776..170778,170824..170829,170890..170892,
                     171139..171141)
                     /gene="fhuD"
                     /locus_tag="b0152"
                     /gene_synonym="ECK0151; JW0148"
                     /note="siderophore binding site; other site"
                     /db_xref="CDD:238566"
     gene            171462..173444
                     /gene="fhuB"
                     /locus_tag="b0153"
                     /gene_synonym="ECK0152; JW0149"
                     /db_xref="EcoGene:EG10303"
                     /db_xref="GeneID:946890"
     CDS             171462..173444
                     /gene="fhuB"
                     /locus_tag="b0153"
                     /gene_synonym="ECK0152; JW0149"
                     /function="transport; Transport of small molecules:
                     Cations"
                     /GO_component="GO:0009274 - peptidoglycan-based cell wall"
                     /GO_component="GO:0019866 - organelle inner membrane"
                     /codon_start=1
                     /transl_table=11
                     /product="iron(3+)-hydroxamate import ABC transporter
                     permease"
                     /protein_id="NP_414695.1"
                     /db_xref="GI:16128146"
                     /db_xref="ASAP:ABE-0000526"
                     /db_xref="UniProtKB/Swiss-Prot:P06972"
                     /db_xref="EcoGene:EG10303"
                     /db_xref="GeneID:946890"
                     /translation="MSKRIALFPALLLALLVIVATALTWMNFSQALPRSQWAQAAWSP
                     DIDVIEQMIFHYSLLPRLAISLLVGAGLGLVGVLFQQVLRNPLAEPTTLGVATGAQLG
                     ITVTTLWAIPGAMASQFAAQAGACVVGLIVFGVAWGKRLSPVTLILAGLVVSLYCGAI
                     NQLLVIFHHDQLQSMFLWSTGTLTQTDWGGVERLWPQLLGGVMLTLLLLRPLTLMGLD
                     DGVARNLGLALSLARLAALSLAIVISALLVNAVGIIGFIGLFAPLLAKMLGARRLLPR
                     LMLASLIGALILWLSDQIILWLTRVWMEVSTGSVTALIGAPLLLWLLPRLRSISAPDM
                     KVNDRVAAERQHVLAFALAGGVLLLMAVVVALSFGRDAHGWTWASGALLEDLMPWRWP
                     RIMAALFAGVMLAVAGCIIQRLTGNPMASPEVLGISSGAAFGVVLMLFLVPGNAFGWL
                     LPAGSLGAAVTLLIIMIAAGRGGFSPHRMLLAGMALSTAFTMLLMMLQASGDPRMAQV
                     LTWISGSTYNATDAQVWRTGIVMVILLAITPLCRRWLTILPLGGDTARAVGMALTPTR
                     IALLLLAACLTATATMTIGPLSFVGLMAPHIARMMGFRRTMPHIVISALVGGLLLVFA
                     DWCGRMVLFPFQIPAGLLSTFIGAPYFIYLLRKQSR"
     misc_feature    171462..173441
                     /gene="fhuB"
                     /locus_tag="b0153"
                     /gene_synonym="ECK0152; JW0149"
                     /note="iron-hydroxamate transporter permease subunit;
                     Provisional; Region: PRK10577"
                     /db_xref="CDD:236720"
     misc_feature    171645..172409
                     /gene="fhuB"
                     /locus_tag="b0153"
                     /gene_synonym="ECK0152; JW0149"
                     /note="Transmembrane subunit (TM), of Periplasmic Binding
                     Protein (PBP)-dependent ATP-Binding Cassette (ABC)
                     transporters involved in the uptake of siderophores, heme,
                     vitamin B12, or the divalent cations Mg2+ and Zn2+.
                     PBP-dependent ABC transporters consist of...; Region:
                     TM_ABC_iron-siderophores_like; cd06550"
                     /db_xref="CDD:119348"
     misc_feature    order(171699..171701,171711..171719,172077..172082,
                     172086..172094,172098..172103,172107..172124,
                     172128..172136,172257..172259,172278..172280)
                     /gene="fhuB"
                     /locus_tag="b0153"
                     /gene_synonym="ECK0152; JW0149"
                     /note="ABC-ATPase subunit  interface; other site"
                     /db_xref="CDD:119348"
     misc_feature    order(171714..171716,171720..171722,171735..171737,
                     171894..171896,171900..171905,171912..171917,
                     171924..171929,171936..171938,171945..171950,
                     171954..171956,171987..171992,171999..172001,
                     172227..172229,172386..172388,172395..172400,
                     172407..172409)
                     /gene="fhuB"
                     /locus_tag="b0153"
                     /gene_synonym="ECK0152; JW0149"
                     /note="dimer interface [polypeptide binding]; other site"
                     /db_xref="CDD:119348"
     misc_feature    order(171954..171956,172029..172031,172203..172205,
                     172215..172217,172347..172349,172377..172379)
                     /gene="fhuB"
                     /locus_tag="b0153"
                     /gene_synonym="ECK0152; JW0149"
                     /note="putative PBP binding regions; other site"
                     /db_xref="CDD:119348"
     misc_feature    172641..173426
                     /gene="fhuB"
                     /locus_tag="b0153"
                     /gene_synonym="ECK0152; JW0149"
                     /note="Transmembrane subunit (TM), of Periplasmic Binding
                     Protein (PBP)-dependent ATP-Binding Cassette (ABC)
                     transporters involved in the uptake of siderophores, heme,
                     vitamin B12, or the divalent cations Mg2+ and Zn2+.
                     PBP-dependent ABC transporters consist of...; Region:
                     TM_ABC_iron-siderophores_like; cd06550"
                     /db_xref="CDD:119348"
     misc_feature    order(172695..172697,172707..172715,173076..173081,
                     173085..173093,173097..173102,173106..173123,
                     173127..173135,173256..173258,173277..173279)
                     /gene="fhuB"
                     /locus_tag="b0153"
                     /gene_synonym="ECK0152; JW0149"
                     /note="ABC-ATPase subunit  interface; other site"
                     /db_xref="CDD:119348"
     misc_feature    order(172710..172712,172716..172718,172731..172733,
                     172893..172895,172899..172904,172911..172916,
                     172923..172928,172935..172937,172944..172949,
                     172953..172955,172986..172991,172998..173000,
                     173226..173228,173382..173384,173391..173396,
                     173403..173405,173412..173417,173424..173426)
                     /gene="fhuB"
                     /locus_tag="b0153"
                     /gene_synonym="ECK0152; JW0149"
                     /note="dimer interface [polypeptide binding]; other site"
                     /db_xref="CDD:119348"
     misc_feature    order(172953..172955,173028..173030,173202..173204,
                     173214..173216,173346..173348,173373..173375)
                     /gene="fhuB"
                     /locus_tag="b0153"
                     /gene_synonym="ECK0152; JW0149"
                     /note="putative PBP binding regions; other site"
                     /db_xref="CDD:119348"
     repeat_region   173504..173588
                     /note="REP13 (repetitive extragenic palindromic) element;
                     contains 2 REP sequences"
     gene            complement(173602..174882)
                     /gene="hemL"
                     /locus_tag="b0154"
                     /gene_synonym="ECK0153; gsa?; JW0150; popC"
                     /db_xref="EcoGene:EG10432"
                     /db_xref="GeneID:946892"
     CDS             complement(173602..174882)
                     /gene="hemL"
                     /locus_tag="b0154"
                     /gene_synonym="ECK0153; gsa?; JW0150; popC"
                     /EC_number="5.4.3.8"
                     /function="enzyme; Biosynthesis of cofactors, carriers:
                     Heme, porphyrin"
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate-1-semialdehyde aminotransferase
                     (aminomutase)"
                     /protein_id="NP_414696.1"
                     /db_xref="GI:16128147"
                     /db_xref="ASAP:ABE-0000529"
                     /db_xref="UniProtKB/Swiss-Prot:P23893"
                     /db_xref="EcoGene:EG10432"
                     /db_xref="GeneID:946892"
                     /translation="MSKSENLYSAARELIPGGVNSPVRAFTGVGGTPLFIEKADGAYL
                     YDVDGKAYIDYVGSWGPMVLGHNHPAIRNAVIEAAERGLSFGAPTEMEVKMAQLVTEL
                     VPTMDMVRMVNSGTEATMSAIRLARGFTGRDKIIKFEGCYHGHADCLLVKAGSGALTL
                     GQPNSPGVPADFAKYTLTCTYNDLASVRAAFEQYPQEIACIIVEPVAGNMNCVPPLPE
                     FLPGLRALCDEFGALLIIDEVMTGFRVALAGAQDYYGVVPDLTCLGKIIGGGMPVGAF
                     GGRRDVMDALAPTGPVYQAGTLSGNPIAMAAGFACLNEVAQPGVHETLDELTTRLAEG
                     LLEAAEEAGIPLVVNHVGGMFGIFFTDAESVTCYQDVMACDVERFKRFFHMMLDEGVY
                     LAPSAFEAGFMSVAHSMEDINNTIDAARRVFAKL"
     misc_feature    complement(173605..174882)
                     /gene="hemL"
                     /locus_tag="b0154"
                     /gene_synonym="ECK0153; gsa?; JW0150; popC"
                     /note="glutamate-1-semialdehyde aminotransferase;
                     Provisional; Region: PRK00062"
                     /db_xref="CDD:234607"
     misc_feature    complement(173614..174864)
                     /gene="hemL"
                     /locus_tag="b0154"
                     /gene_synonym="ECK0153; gsa?; JW0150; popC"
                     /note="Acetyl ornithine aminotransferase family. This
                     family belongs to pyridoxal phosphate (PLP)-dependent
                     aspartate aminotransferase superfamily (fold I). The major
                     groups in this CD correspond to ornithine
                     aminotransferase, acetylornithine aminotransferase;
                     Region: OAT_like; cd00610"
                     /db_xref="CDD:99735"
     misc_feature    complement(order(174088..174090,174163..174168,
                     174172..174174,174271..174273,174448..174450,
                     174454..174459,174535..174543))
                     /gene="hemL"
                     /locus_tag="b0154"
                     /gene_synonym="ECK0153; gsa?; JW0150; popC"
                     /note="inhibitor-cofactor binding pocket; inhibition site"
                     /db_xref="CDD:99735"
     misc_feature    complement(order(174088..174090,174163..174165,
                     174172..174174,174271..174273,174454..174459,
                     174535..174540))
                     /gene="hemL"
                     /locus_tag="b0154"
                     /gene_synonym="ECK0153; gsa?; JW0150; popC"
                     /note="pyridoxal 5'-phosphate binding site [chemical
                     binding]; other site"
                     /db_xref="CDD:99735"
     misc_feature    complement(174088..174090)
                     /gene="hemL"
                     /locus_tag="b0154"
                     /gene_synonym="ECK0153; gsa?; JW0150; popC"
                     /note="catalytic residue [active]"
                     /db_xref="CDD:99735"
     gene            175107..176528
                     /gene="clcA"
                     /locus_tag="b0155"
                     /gene_synonym="ECK0154; eriC; JW5012; yadQ"
                     /db_xref="EcoGene:EG12331"
                     /db_xref="GeneID:946715"
     CDS             175107..176528
                     /gene="clcA"
                     /locus_tag="b0155"
                     /gene_synonym="ECK0154; eriC; JW5012; yadQ"
                     /function="transport; Not classified"
                     /note="putative channel transporter"
                     /codon_start=1
                     /transl_table=11
                     /product="H(+)/Cl(-) exchange transporter"
                     /protein_id="NP_414697.1"
                     /db_xref="GI:16128148"
                     /db_xref="ASAP:ABE-0000533"
                     /db_xref="UniProtKB/Swiss-Prot:P37019"
                     /db_xref="EcoGene:EG12331"
                     /db_xref="GeneID:946715"
                     /translation="MKTDTPSLETPQAARLRRRQLIRQLLERDKTPLAILFMAAVVGT
                     LVGLAAVAFDKGVAWLQNQRMGALVHTADNYPLLLTVAFLCSAVLAMFGYFLVRKYAP
                     EAGGSGIPEIEGALEDQRPVRWWRVLPVKFFGGLGTLGGGMVLGREGPTVQIGGNIGR
                     MVLDIFRLKGDEARHTLLATGAAAGLAAAFNAPLAGILFIIEEMRPQFRYTLISIKAV
                     FIGVIMSTIMYRIFNHEVALIDVGKLSDAPLNTLWLYLILGIIFGIFGPIFNKWVLGM
                     QDLLHRVHGGNITKWVLMGGAIGGLCGLLGFVAPATSGGGFNLIPIATAGNFSMGMLV
                     FIFVARVITTLLCFSSGAPGGIFAPMLALGTVLGTAFGMVAVELFPQYHLEAGTFAIA
                     GMGALLAASIRAPLTGIILVLEMTDNYQLILPMIITGLGATLLAQFTGGKPLYSAILA
                     RTLAKQEAEQLARSKAASASENT"
     misc_feature    175230..176456
                     /gene="clcA"
                     /locus_tag="b0155"
                     /gene_synonym="ECK0154; eriC; JW5012; yadQ"
                     /note="ClC chloride channel EriC.  This domain is found in
                     the EriC chloride transporters that mediate the extreme
                     acid resistance response in eubacteria and archaea. This
                     response allows bacteria to survive in the acidic
                     environments by decarboxylation-linked...; Region: EriC;
                     cd01031"
                     /db_xref="CDD:238504"
     misc_feature    order(175422..175436,175542..175556,176169..176183,
                     176439..176441)
                     /gene="clcA"
                     /locus_tag="b0155"
                     /gene_synonym="ECK0154; eriC; JW5012; yadQ"
                     /note="Cl- selectivity filter; other site"
                     /db_xref="CDD:238504"
     misc_feature    order(175425..175427,175431..175433,175548..175553,
                     176169..176177,176439..176441)
                     /gene="clcA"
                     /locus_tag="b0155"
                     /gene_synonym="ECK0154; eriC; JW5012; yadQ"
                     /note="Cl- binding residues [ion binding]; other site"
                     /db_xref="CDD:238504"
     misc_feature    175548..175550
                     /gene="clcA"
                     /locus_tag="b0155"
                     /gene_synonym="ECK0154; eriC; JW5012; yadQ"
                     /note="pore gating glutamate residue; other site"
                     /db_xref="CDD:238504"
     misc_feature    order(175686..175688,175713..175715,175752..175754,
                     175773..175775,176313..176315,176322..176324,
                     176346..176348,176382..176384,176403..176408,
                     176415..176417)
                     /gene="clcA"
                     /locus_tag="b0155"
                     /gene_synonym="ECK0154; eriC; JW5012; yadQ"
                     /note="dimer interface [polypeptide binding]; other site"
                     /db_xref="CDD:238504"
     misc_feature    175713..175715
                     /gene="clcA"
                     /locus_tag="b0155"
                     /gene_synonym="ECK0154; eriC; JW5012; yadQ"
                     /note="H+/Cl- coupling transport residue; other site"
                     /db_xref="CDD:238504"
     gene            176610..176954
                     /gene="erpA"
                     /locus_tag="b0156"
                     /gene_synonym="ECK0155; JW0152; yadR"
                     /db_xref="EcoGene:EG12332"
                     /db_xref="GeneID:944857"
     CDS             176610..176954
                     /gene="erpA"
                     /locus_tag="b0156"
                     /gene_synonym="ECK0155; JW0152; yadR"
                     /codon_start=1
                     /transl_table=11
                     /product="iron-sulfur cluster insertion protein"
                     /protein_id="NP_414698.1"
                     /db_xref="GI:16128149"
                     /db_xref="ASAP:ABE-0000538"
                     /db_xref="UniProtKB/Swiss-Prot:P0ACC3"
                     /db_xref="EcoGene:EG12332"
                     /db_xref="GeneID:944857"
                     /translation="MSDDVALPLEFTDAAANKVKSLIADEDNPNLKLRVYITGGGCSG
                     FQYGFTFDDQVNEGDMTIEKQGVGLVVDPMSLQYLVGGSVDYTEGLEGSRFIVTNPNA
                     KSTCGCGSSFSI"
     misc_feature    176610..176951
                     /gene="erpA"
                     /locus_tag="b0156"
                     /gene_synonym="ECK0155; JW0152; yadR"
                     /note="iron-sulfur cluster insertion protein ErpA;
                     Provisional; Region: PRK13623"
                     /db_xref="CDD:184186"
     repeat_region   176969..176987
                     /note="REP14 (repetitive extragenic palindromic) element;
                     contains 1 REP sequences"
     gene            complement(177001..177624)
                     /gene="yadS"
                     /locus_tag="b0157"
                     /gene_synonym="ECK0156; JW0153"
                     /db_xref="EcoGene:EG12333"
                     /db_xref="GeneID:949062"
     CDS             complement(177001..177624)
                     /gene="yadS"
                     /locus_tag="b0157"
                     /gene_synonym="ECK0156; JW0153"
                     /codon_start=1
                     /transl_table=11
                     /product="UPF0126 family inner membrane protein"
                     /protein_id="NP_414699.1"
                     /db_xref="GI:16128150"
                     /db_xref="ASAP:ABE-0000540"
                     /db_xref="UniProtKB/Swiss-Prot:P0AFP0"
                     /db_xref="EcoGene:EG12333"
                     /db_xref="GeneID:949062"
                     /translation="MLVYWLDIVGTAVFAISGVLLAGKLRMDPFGVLVLGVVTAVGGG
                     TIRDMALDHGPVFWVKDPTDLVVAMVTSMLTIVLVRQPRRLPKWMLPVLDAVGLAVFV
                     GIGVNKAFNAEAGPLIAVCMGVITGVGGGIIRDVLAREIPMILRTEIYATACIIGGIV
                     HATAYYTFSVPLETASMMGMVVTLLIRLAAIRWHLKLPTFALDENGR"
     misc_feature    complement(177004..177624)
                     /gene="yadS"
                     /locus_tag="b0157"
                     /gene_synonym="ECK0156; JW0153"
                     /note="hypothetical protein; Provisional; Region:
                     PRK10578"
                     /db_xref="CDD:182564"
     misc_feature    complement(177385..177618)
                     /gene="yadS"
                     /locus_tag="b0157"
                     /gene_synonym="ECK0156; JW0153"
                     /note="UPF0126 domain; Region: UPF0126; pfam03458"
                     /db_xref="CDD:251969"
     misc_feature    complement(177145..177357)
                     /gene="yadS"
                     /locus_tag="b0157"
                     /gene_synonym="ECK0156; JW0153"
                     /note="UPF0126 domain; Region: UPF0126; pfam03458"
                     /db_xref="CDD:251969"
     gene            complement(177662..178462)
                     /gene="btuF"
                     /locus_tag="b0158"
                     /gene_synonym="ECK0157; JW0154; yadT"
                     /db_xref="EcoGene:EG12334"
                     /db_xref="GeneID:947574"
     CDS             complement(177662..178462)
                     /gene="btuF"
                     /locus_tag="b0158"
                     /gene_synonym="ECK0157; JW0154; yadT"
                     /GO_component="GO:0042597 - periplasmic space"
                     /codon_start=1
                     /transl_table=11
                     /product="vitamin B12 ABC transporter periplasmic binding
                     protein"
                     /protein_id="NP_414700.1"
                     /db_xref="GI:16128151"
                     /db_xref="ASAP:ABE-0000542"
                     /db_xref="UniProtKB/Swiss-Prot:P37028"
                     /db_xref="EcoGene:EG12334"
                     /db_xref="GeneID:947574"
                     /translation="MAKSLFRALVALSFLAPLWLNAAPRVITLSPANTELAFAAGITP
                     VGVSSYSDYPPQAQKIEQVSTWQGMNLERIVALKPDLVIAWRGGNAERQVDQLASLGI
                     KVMWVDATSIEQIANALRQLAPWSPQPDKAEQAAQSLLDQYAQLKAQYADKPKKRVFL
                     QFGINPPFTSGKESIQNQVLEVCGGENIFKDSRVPWPQVSREQVLARSPQAIVITGGP
                     DQIPKIKQYWGEQLKIPVIPLTSDWFERASPRIILAAQQLCNALSQVD"
     misc_feature    complement(177671..178390)
                     /gene="btuF"
                     /locus_tag="b0158"
                     /gene_synonym="ECK0157; JW0154; yadT"
                     /note="ABC-type Fe3+-hydroxamate transport system,
                     periplasmic component [Inorganic ion transport and
                     metabolism]; Region: FepB; COG0614"
                     /db_xref="CDD:223687"
     misc_feature    complement(177683..178390)
                     /gene="btuF"
                     /locus_tag="b0158"
                     /gene_synonym="ECK0157; JW0154; yadT"
                     /note="Cobalamin binding protein BtuF.  These proteins
                     have been shown to function as initial receptors in ABC
                     transport of vitamin B12 (cobalamin) in eubacterial and
                     some archaeal species.  They belong to the TroA
                     superfamily of helical backbone metal receptor...; Region:
                     BtuF; cd01144"
                     /db_xref="CDD:238564"
     misc_feature    complement(order(177875..177877,177959..177961,
                     178202..178204,178208..178210,178313..178315,
                     178367..178372))
                     /gene="btuF"
                     /locus_tag="b0158"
                     /gene_synonym="ECK0157; JW0154; yadT"
                     /note="cobalamin binding residues [chemical binding];
                     other site"
                     /db_xref="CDD:238564"
     misc_feature    complement(order(177857..177859,178247..178249))
                     /gene="btuF"
                     /locus_tag="b0158"
                     /gene_synonym="ECK0157; JW0154; yadT"
                     /note="putative BtuC binding residues; other site"
                     /db_xref="CDD:238564"
     misc_feature    complement(order(178100..178105,178112..178114,
                     178121..178126,178130..178132,178139..178141,
                     178151..178153,178169..178171,178178..178180,
                     178205..178207))
                     /gene="btuF"
                     /locus_tag="b0158"
                     /gene_synonym="ECK0157; JW0154; yadT"
                     /note="dimer interface [polypeptide binding]; other site"
                     /db_xref="CDD:238564"
     gene            complement(178455..179153)
                     /gene="mtn"
                     /locus_tag="b0159"
                     /gene_synonym="ECK0158; JW0155; mtnN; pfs; yadA"
                     /db_xref="EcoGene:EG11090"
                     /db_xref="GeneID:948542"
     CDS             complement(178455..179153)
                     /gene="mtn"
                     /locus_tag="b0159"
                     /gene_synonym="ECK0158; JW0155; mtnN; pfs; yadA"
                     /EC_number="3.2.2.16"
                     /EC_number="3.2.2.9"
                     /GO_process="GO:0015949 - nucleobase, nucleoside and
                     nucleotide interconversion"
                     /codon_start=1
                     /transl_table=11
                     /product="5'-methylthioadenosine/S-adenosylhomocysteine
                     nucleosidase"
                     /protein_id="NP_414701.1"
                     /db_xref="GI:16128152"
                     /db_xref="ASAP:ABE-0000545"
                     /db_xref="UniProtKB/Swiss-Prot:P0AF12"
                     /db_xref="EcoGene:EG11090"
                     /db_xref="GeneID:948542"
                     /translation="MKIGIIGAMEEEVTLLRDKIENRQTISLGGCEIYTGQLNGTEVA
                     LLKSGIGKVAAALGATLLLEHCKPDVIINTGSAGGLAPTLKVGDIVVSDEARYHDADV
                     TAFGYEYGQLPGCPAGFKADDKLIAAAEACIAELNLNAVRGLIVSGDAFINGSVGLAK
                     IRHNFPQAIAVEMEATAIAHVCHNFNVPFVVVRAISDVADQQSHLSFDEFLAVAAKQS
                     SLMVESLVQKLAHG"
     misc_feature    complement(178464..179153)
                     /gene="mtn"
                     /locus_tag="b0159"
                     /gene_synonym="ECK0158; JW0155; mtnN; pfs; yadA"
                     /note="5'-methylthioadenosine/S-adenosylhomocysteine
                     nucleosidase; Validated; Region: PRK05584"
                     /db_xref="CDD:180148"
     gene            179237..180754
                     /gene="dgt"
                     /locus_tag="b0160"
                     /gene_synonym="ECK0159; JW0156; optA"
                     /db_xref="EcoGene:EG10225"
                     /db_xref="GeneID:947177"
     CDS             179237..180754
                     /gene="dgt"
                     /locus_tag="b0160"
                     /gene_synonym="ECK0159; JW0156; optA"
                     /EC_number="3.1.5.1"
                     /function="enzyme; Central intermediary metabolism:
                     Nucleotide hydrolysis"
                     /GO_component="GO:0005737 - cytoplasm"
                     /GO_process="GO:0015949 - nucleobase, nucleoside and
                     nucleotide interconversion"
                     /codon_start=1
                     /transl_table=11
                     /product="deoxyguanosine triphosphate triphosphohydrolase"
                     /protein_id="NP_414702.1"
                     /db_xref="GI:16128153"
                     /db_xref="ASAP:ABE-0000548"
                     /db_xref="UniProtKB/Swiss-Prot:P15723"
                     /db_xref="EcoGene:EG10225"
                     /db_xref="GeneID:947177"
                     /translation="MAQIDFRKKINWHRRYRSPQGVKTEHEILRIFESDRGRIINSPA
                     IRRLQQKTQVFPLERNAAVRTRLTHSMEVQQVGRYIAKEILSRLKELKLLEAYGLDEL
                     TGPFESIVEMSCLMHDIGNPPFGHFGEAAINDWFRQRLHPEDAESQPLTDDRCSVAAL
                     RLRDGEEPLNELRRKIRQDLCHFEGNAQGIRLVHTLMRMNLTWAQVGGILKYTRPAWW
                     RGETPETHHYLMKKPGYYLSEEAYIARLRKELNLALYSRFPLTWIMEAADDISYCVAD
                     LEDAVEKRIFTVEQLYHHLHEAWGQHEKGSLFSLVVENAWEKSRSNSLSRSTEDQFFM
                     YLRVNTLNKLVPYAAQRFIDNLPAIFAGTFNHALLEDASECSDLLKLYKNVAVKHVFS
                     HPDVERLELQGYRVISGLLEIYRPLLSLSLSDFTELVEKERVKRFPIESRLFHKLSTR
                     HRLAYVEAVSKLPSDSPEFPLWEYYYRCRLLQDYISGMTDLYAWDEYRRLMAVEQ"
     misc_feature    179237..180748
                     /gene="dgt"
                     /locus_tag="b0160"
                     /gene_synonym="ECK0159; JW0156; optA"
                     /note="deoxyguanosinetriphosphate triphosphohydrolase;
                     Provisional; Region: dgt; PRK04926"
                     /db_xref="CDD:235320"
     misc_feature    179426..>179674
                     /gene="dgt"
                     /locus_tag="b0160"
                     /gene_synonym="ECK0159; JW0156; optA"
                     /note="Metal dependent phosphohydrolases with conserved
                     'HD' motif; Region: HDc; cd00077"
                     /db_xref="CDD:238032"
     misc_feature    order(179441..179443,179585..179590)
                     /gene="dgt"
                     /locus_tag="b0160"
                     /gene_synonym="ECK0159; JW0156; optA"
                     /note="Zn2+ binding site [ion binding]; other site"
                     /db_xref="CDD:238032"
     misc_feature    179588..179590
                     /gene="dgt"
                     /locus_tag="b0160"
                     /gene_synonym="ECK0159; JW0156; optA"
                     /note="Mg2+ binding site [ion binding]; other site"
                     /db_xref="CDD:238032"
     misc_feature    180371..180733
                     /gene="dgt"
                     /locus_tag="b0160"
                     /gene_synonym="ECK0159; JW0156; optA"
                     /note="Phosphohydrolase-associated domain; Region:
                     HD_assoc; pfam13286"
                     /db_xref="CDD:257627"
     gene            180884..182308
                     /gene="degP"
                     /locus_tag="b0161"
                     /gene_synonym="ECK0160; htrA; JW0157; ptd"
                     /db_xref="EcoGene:EG10463"
                     /db_xref="GeneID:947139"
     CDS             180884..182308
                     /gene="degP"
                     /locus_tag="b0161"
                     /gene_synonym="ECK0160; htrA; JW0157; ptd"
                     /EC_number="3.4.21.-"
                     /function="enzyme; Degradation of proteins, peptides,
                     glycopeptides"
                     /GO_component="GO:0042597 - periplasmic space"
                     /GO_process="GO:0009266 - response to temperature
                     stimulus"
                     /note="periplasmic serine protease Do; heat shock protein
                     HtrA"
                     /codon_start=1
                     /transl_table=11
                     /product="serine endoprotease (protease Do),
                     membrane-associated"
                     /protein_id="NP_414703.1"
                     /db_xref="GI:16128154"
                     /db_xref="ASAP:ABE-0000551"
                     /db_xref="UniProtKB/Swiss-Prot:P0C0V0"
                     /db_xref="EcoGene:EG10463"
                     /db_xref="GeneID:947139"
                     /translation="MKKTTLALSALALSLGLALSPLSATAAETSSATTAQQMPSLAPM
                     LEKVMPSVVSINVEGSTTVNTPRMPRNFQQFFGDDSPFCQEGSPFQSSPFCQGGQGGN
                     GGGQQQKFMALGSGVIIDADKGYVVTNNHVVDNATVIKVQLSDGRKFDAKMVGKDPRS
                     DIALIQIQNPKNLTAIKMADSDALRVGDYTVAIGNPFGLGETVTSGIVSALGRSGLNA
                     ENYENFIQTDAAINRGNSGGALVNLNGELIGINTAILAPDGGNIGIGFAIPSNMVKNL
                     TSQMVEYGQVKRGELGIMGTELNSELAKAMKVDAQRGAFVSQVLPNSSAAKAGIKAGD
                     VITSLNGKPISSFAALRAQVGTMPVGSKLTLGLLRDGKQVNVNLELQQSSQNQVDSSS
                     IFNGIEGAEMSNKGKDQGVVVNNVKTGTPAAQIGLKKGDVIIGANQQAVKNIAELRKV
                     LDSKPSVLALNIQRGDSTIYLLMQ"
     misc_feature    180887..182305
                     /gene="degP"
                     /locus_tag="b0161"
                     /gene_synonym="ECK0160; htrA; JW0157; ptd"
                     /note="serine endoprotease; Provisional; Region: PRK10942"
                     /db_xref="CDD:236802"
     misc_feature    181223..181633
                     /gene="degP"
                     /locus_tag="b0161"
                     /gene_synonym="ECK0160; htrA; JW0157; ptd"
                     /note="Trypsin-like peptidase domain; Region: Trypsin_2;
                     pfam13365"
                     /db_xref="CDD:257693"
     misc_feature    181754..182017
                     /gene="degP"
                     /locus_tag="b0161"
                     /gene_synonym="ECK0160; htrA; JW0157; ptd"
                     /note="PDZ domain of trypsin-like serine proteases, such
                     as DegP/HtrA, which are oligomeric proteins involved in
                     heat-shock response, chaperone function, and apoptosis.
                     May be responsible for substrate recognition and/or
                     binding, as most PDZ domains bind...; Region:
                     PDZ_serine_protease; cd00987"
                     /db_xref="CDD:238487"
     misc_feature    order(181754..181762,181766..181768,181919..181924,
                     181931..181936)
                     /gene="degP"
                     /locus_tag="b0161"
                     /gene_synonym="ECK0160; htrA; JW0157; ptd"
                     /note="protein binding site [polypeptide binding]; other
                     site"
                     /db_xref="CDD:238487"
     misc_feature    182063..182296
                     /gene="degP"
                     /locus_tag="b0161"
                     /gene_synonym="ECK0160; htrA; JW0157; ptd"
                     /note="PDZ domain of trypsin-like serine proteases, such
                     as DegP/HtrA, which are oligomeric proteins involved in
                     heat-shock response, chaperone function, and apoptosis.
                     May be responsible for substrate recognition and/or
                     binding, as most PDZ domains bind...; Region:
                     PDZ_serine_protease; cd00987"
                     /db_xref="CDD:238487"
     misc_feature    order(182063..182074,182078..182080,182210..182215,
                     182222..182227)
                     /gene="degP"
                     /locus_tag="b0161"
                     /gene_synonym="ECK0160; htrA; JW0157; ptd"
                     /note="protein binding site [polypeptide binding]; other
                     site"
                     /db_xref="CDD:238487"
     gene            182463..183620
                     /gene="cdaR"
                     /locus_tag="b0162"
                     /gene_synonym="ECK0161; JW5013; sdaR; yaeG"
                     /db_xref="EcoGene:EG12335"
                     /db_xref="GeneID:944860"
     CDS             182463..183620
                     /gene="cdaR"
                     /locus_tag="b0162"
                     /gene_synonym="ECK0161; JW5013; sdaR; yaeG"
                     /function="regulator; Not classified"
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate diacid regulon transcriptional
                     regulator; autoregulator"
                     /protein_id="NP_414704.4"
                     /db_xref="GI:90111093"
                     /db_xref="ASAP:ABE-0000554"
                     /db_xref="UniProtKB/Swiss-Prot:P37047"
                     /db_xref="EcoGene:EG12335"
                     /db_xref="GeneID:944860"
                     /translation="MAGWHLDTKMAQDIVARTMRIIDTNINVMDARGRIIGSGDRERI
                     GELHEGALLVLSQGRVVDIDDAVARHLHGVRQGINLPLRLEGEIVGVIGLTGEPENLR
                     KYGELVCMTAEMMLEQSRLMHLLAQDSRLREELVMNLIQAEENTPALTEWAQRLGIDL
                     NQPRVVAIVEVDSGQLGVDSAMAELQQLQNALTTPERNNLVAIVSLTEMVVLKPALNS
                     FGRWDAEDHRKRVEQLITRMKEYGQLRFRVSLGNYFTGPGSIARSYRTAKTTMVVGKQ
                     RMPESRCYFYQDLMLPVLLDSLRGDWQANELARPLARLKTMDNNGLLRRTLAAWFRHN
                     VQPLATSKALFIHRNTLEYRLNRISELTGLDLGNFDDRLLLYVALQLDEER"
     misc_feature    182463..183617
                     /gene="cdaR"
                     /locus_tag="b0162"
                     /gene_synonym="ECK0161; JW5013; sdaR; yaeG"
                     /note="carbohydrate diacid transcriptional activator CdaR;
                     Provisional; Region: PRK11477"
                     /db_xref="CDD:183155"
     misc_feature    182478..182882
                     /gene="cdaR"
                     /locus_tag="b0162"
                     /gene_synonym="ECK0161; JW5013; sdaR; yaeG"
                     /note="Putative sugar diacid recognition; Region:
                     Diacid_rec; pfam05651"
                     /db_xref="CDD:147680"
     misc_feature    183438..183605
                     /gene="cdaR"
                     /locus_tag="b0162"
                     /gene_synonym="ECK0161; JW5013; sdaR; yaeG"
                     /note="PucR C-terminal helix-turn-helix domain; Region:
                     HTH_30; pfam13556"
                     /db_xref="CDD:257873"
     gene            complement(183709..184095)
                     /gene="yaeH"
                     /locus_tag="b0163"
                     /gene_synonym="ECK0162; JW0159"
                     /db_xref="EcoGene:EG12336"
                     /db_xref="GeneID:947044"
     CDS             complement(183709..184095)
                     /gene="yaeH"
                     /locus_tag="b0163"
                     /gene_synonym="ECK0162; JW0159"
                     /function="putative structure; Not classified"
                     /note="putative structural protein"
                     /codon_start=1
                     /transl_table=11
                     /product="UPF0325 family protein"
                     /protein_id="NP_414705.1"
                     /db_xref="GI:16128156"
                     /db_xref="ASAP:ABE-0000556"
                     /db_xref="UniProtKB/Swiss-Prot:P62768"
                     /db_xref="EcoGene:EG12336"
                     /db_xref="GeneID:947044"
                     /translation="MYDNLKSLGITNPEEIDRYSLRQEANNDILKIYFQKDKGEFFAK
                     SVKFKYPRQRKTVVADGVGQGYKEVQEISPNLRYIIDELDQICQRDRSEVDLKRKILD
                     DLRHLESVVTNKISEIEADLEKLTRK"
     misc_feature    complement(183721..184095)
                     /gene="yaeH"
                     /locus_tag="b0163"
                     /gene_synonym="ECK0162; JW0159"
                     /note="hypothetical protein; Provisional; Region:
                     PRK13677"
                     /db_xref="CDD:184234"
     gene            complement(184257..185069)
                     /gene="yaeI"
                     /locus_tag="b0164"
                     /gene_synonym="ECK0163; JW5014"
                     /db_xref="EcoGene:EG12337"
                     /db_xref="GeneID:945002"
     CDS             complement(184257..185069)
                     /gene="yaeI"
                     /locus_tag="b0164"
                     /gene_synonym="ECK0163; JW5014"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphodiesterase with model substrate bis-pNPP"
                     /protein_id="NP_414706.2"
                     /db_xref="GI:90111094"
                     /db_xref="ASAP:ABE-0000559"
                     /db_xref="UniProtKB/Swiss-Prot:P37049"
                     /db_xref="EcoGene:EG12337"
                     /db_xref="GeneID:945002"
                     /translation="MISRRRFLQATAATIATSSGFGYMHYCEPGWFELIRHRLAFFKD
                     NAAPFKILFLADLHYSRFVPLSLISDAIALGIEQKPDLILLGGDYVLFDMSLNFSAFS
                     DVLSPLAECAPTFACFGNHDRPVGTEKNHLIGETLKSAGITVLFNQATVIATPNRQFE
                     LVGTGDLWAGQCKPPPASEANLPRLVLAHNPDSKEVMRDEPWDLMLCGHTHGGQLRVP
                     LVGEPFAPVEDKRYVAGLNAFGERHIYTTRGVGSLYGLRLNCRPEVTMLELV"
     misc_feature    complement(184263..184928)
                     /gene="yaeI"
                     /locus_tag="b0164"
                     /gene_synonym="ECK0163; JW5014"
                     /note="Bacillus subtilis YkuE and related proteins,
                     C-terminal metallophosphatase domain; Region: MPP_YkuE_C;
                     cd07385"
                     /db_xref="CDD:163628"
     misc_feature    complement(order(184437..184439,184443..184445,
                     184503..184505,184707..184712,184806..184808,
                     184896..184898,184902..184904))
                     /gene="yaeI"
                     /locus_tag="b0164"
                     /gene_synonym="ECK0163; JW5014"
                     /note="putative active site [active]"
                     /db_xref="CDD:163628"
     misc_feature    complement(order(184437..184439,184443..184445,
                     184503..184505,184710..184712,184806..184808,
                     184896..184898,184902..184904))
                     /gene="yaeI"
                     /locus_tag="b0164"
                     /gene_synonym="ECK0163; JW5014"
                     /note="putative metal binding site [ion binding]; other
                     site"
                     /db_xref="CDD:163628"
     gene            complement(185123..185947)
                     /gene="dapD"
                     /locus_tag="b0166"
                     /gene_synonym="ECK0164; JW0161; ssa"
                     /db_xref="EcoGene:EG10207"
                     /db_xref="GeneID:944862"
     CDS             complement(185123..185947)
                     /gene="dapD"
                     /locus_tag="b0166"
                     /gene_synonym="ECK0164; JW0161; ssa"
                     /EC_number="2.3.1.117"
                     /function="enzyme; Amino acid biosynthesis: Lysine"
                     /experiment="N-terminus verified by Edman degradation:
                     PMID 8740179,9298646"
                     /GO_component="GO:0005737 - cytoplasm"
                     /GO_process="GO:0009089 - lysine biosynthetic process via
                     diaminopimelate"
                     /codon_start=1
                     /transl_table=11
                     /product="2,3,4,5-tetrahydropyridine-2-carboxylate
                     N-succinyltransferase"
                     /protein_id="NP_414708.1"
                     /db_xref="GI:16128159"
                     /db_xref="ASAP:ABE-0000565"
                     /db_xref="UniProtKB/Swiss-Prot:P0A9D8"
                     /db_xref="EcoGene:EG10207"
                     /db_xref="GeneID:944862"
                     /translation="MQQLQNIIETAFERRAEITPANADTVTREAVNQVIALLDSGALR
                     VAEKIDGQWVTHQWLKKAVLLSFRINDNQVIEGAESRYFDKVPMKFADYDEARFQKEG
                     FRVVPPAAVRQGAFIARNTVLMPSYVNIGAYVDEGTMVDTWATVGSCAQIGKNVHLSG
                     GVGIGGVLEPLQANPTIIEDNCFIGARSEVVEGVIVEEGSVISMGVYIGQSTRIYDRE
                     TGEIHYGRVPAGSVVVSGNLPSKDGKYSLYCAVIVKKVDAKTRGKVGINELLRTID"
     misc_feature    complement(185135..185947)
                     /gene="dapD"
                     /locus_tag="b0166"
                     /gene_synonym="ECK0164; JW0161; ssa"
                     /note="2,3,4,5-tetrahydropyridine-2,6-carboxylate
                     N-succinyltransferase; Provisional; Region: dapD;
                     PRK11830"
                     /db_xref="CDD:236996"
     misc_feature    complement(185741..185944)
                     /gene="dapD"
                     /locus_tag="b0166"
                     /gene_synonym="ECK0164; JW0161; ssa"
                     /note="Tetrahydrodipicolinate N-succinyltransferase
                     N-terminal; Region: THDPS_N_2; pfam14805"
                     /db_xref="CDD:258942"
     misc_feature    complement(185231..185644)
                     /gene="dapD"
                     /locus_tag="b0166"
                     /gene_synonym="ECK0164; JW0161; ssa"
                     /note="2,3,4,5-tetrahydropyridine-2,6-dicarboxylate (THDP)
                     N-succinyltransferase (also called THP
                     succinyltransferase): THDP N-succinyltransferase catalyzes
                     the conversion of tetrahydrodipicolinate and succinyl-CoA
                     to N-succinyltetrahydrodipicolinate and CoA; Region:
                     LbH_THP_succinylT; cd03350"
                     /db_xref="CDD:100041"
     misc_feature    complement(order(185231..185233,185237..185248,
                     185327..185329,185381..185383,185387..185389,
                     185465..185467,185513..185521,185567..185569,
                     185573..185575,185621..185626,185633..185638))
                     /gene="dapD"
                     /locus_tag="b0166"
                     /gene_synonym="ECK0164; JW0161; ssa"
                     /note="trimer interface [polypeptide binding]; other site"
                     /db_xref="CDD:100041"
     misc_feature    complement(order(185336..185341,185372..185374,
                     185387..185395,185432..185434,185441..185446,
                     185450..185452,185471..185473,185477..185479,
                     185504..185506,185525..185527,185561..185563,
                     185576..185578,185612..185614,185636..185638))
                     /gene="dapD"
                     /locus_tag="b0166"
                     /gene_synonym="ECK0164; JW0161; ssa"
                     /note="active site"
                     /db_xref="CDD:100041"
     misc_feature    complement(order(185444..185446,185504..185506,
                     185525..185527,185561..185563,185576..185578,
                     185612..185614,185636..185638))
                     /gene="dapD"
                     /locus_tag="b0166"
                     /gene_synonym="ECK0164; JW0161; ssa"
                     /note="substrate binding site [chemical binding]; other
                     site"
                     /db_xref="CDD:100041"
     misc_feature    complement(order(185336..185341,185372..185374,
                     185387..185395,185432..185434,185450..185452,
                     185468..185473))
                     /gene="dapD"
                     /locus_tag="b0166"
                     /gene_synonym="ECK0164; JW0161; ssa"
                     /note="CoA binding site [chemical binding]; other site"
                     /db_xref="CDD:100041"
     gene            complement(185978..188650)
                     /gene="glnD"
                     /locus_tag="b0167"
                     /gene_synonym="ECK0165; JW0162"
                     /db_xref="EcoGene:EG11411"
                     /db_xref="GeneID:944863"
     CDS             complement(185978..188650)
                     /gene="glnD"
                     /locus_tag="b0167"
                     /gene_synonym="ECK0165; JW0162"
                     /EC_number="2.7.7.59"
                     /function="enzyme; Amino acid biosynthesis: Glutamine"
                     /GO_component="GO:0005737 - cytoplasm"
                     /GO_process="GO:0006807 - nitrogen compound metabolic
                     process"
                     /GO_process="GO:0006542 - glutamine biosynthetic process"
                     /GO_process="GO:0006464 - protein modification process"
                     /note="protein PII; uridylyltransferase acts on regulator
                     of glnA"
                     /codon_start=1
                     /transl_table=11
                     /product="uridylyltransferase"
                     /protein_id="NP_414709.1"
                     /db_xref="GI:16128160"
                     /db_xref="ASAP:ABE-0000568"
                     /db_xref="UniProtKB/Swiss-Prot:P27249"
                     /db_xref="EcoGene:EG11411"
                     /db_xref="GeneID:944863"
                     /translation="MNTLPEQYANTALPTLPGQPQNPCVWPRDELTVGGIKAHIDTFQ
                     RWLGDAFDNGISAEQLIEARTEFIDQLLQRLWIEAGFSQIADLALVAVGGYGRGELHP
                     LSDVDLLILSRKKLPDDQAQKVGELLTLLWDVKLEVGHSVRTLEECMLEGLSDLTVAT
                     NLIESRLLIGDVALFLELQKHIFSEGFWPSDKFYAAKVEEQNQRHQRYHGTSYNLEPD
                     IKSSPGGLRDIHTLQWVARRHFGATSLDEMVGFGFLTSAERAELNECLHILWRIRFAL
                     HLVVSRYDNRLLFDRQLSVAQRLNYSGEGNEPVERMMKDYFRVTRRVSELNQMLLQLF
                     DEAILALPADEKPRPIDDEFQLRGTLIDLRDETLFMRQPEAILRMFYTMVHNSAITGI
                     YSTTLRQLRHARRHLQQPLCNIPEARKLFLSILRHPGAVRRGLLPMHRHSVLGAYMPQ
                     WSHIVGQMQFDLFHAYTVDEHTIRVMLKLESFASEETRQRHPLCVDVWPRLPSTELIF
                     IAALFHDIAKGRGGDHSILGAQDVVHFAELHGLNSRETQLVAWLVRQHLLMSVTAQRR
                     DIQDPEVIKQFAEEVQTENRLRYLVCLTVADICATNETLWNSWKQSLLRELYFATEKQ
                     LRRGMQNTPDMRERVRHHQLQALALLRMDNIDEEALHQIWSRCRANYFVRHSPNQLAW
                     HARHLLQHDLSKPLVLLSPQATRGGTEIFIWSPDRPYLFAAVCAELDRRNLSVHDAQI
                     FTTRDGMAMDTFIVLEPDGNPLSADRHEVIRFGLEQVLTQSSWQPPQPRRQPAKLRHF
                     TVETEVTFLPTHTDRKSFLELIALDQPGLLARVGKIFADLGISLHGARITTIGERVED
                     LFIIATADRRALNNELQQEVHQRLTEALNPNDKG"
     misc_feature    complement(185981..188632)
                     /gene="glnD"
                     /locus_tag="b0167"
                     /gene_synonym="ECK0165; JW0162"
                     /note="PII uridylyl-transferase; Provisional; Region:
                     PRK05007"
                     /db_xref="CDD:235329"
     misc_feature    complement(188102..188500)
                     /gene="glnD"
                     /locus_tag="b0167"
                     /gene_synonym="ECK0165; JW0162"
                     /note="Nucleotidyltransferase (NT) domain of Escherichia
                     coli adenylyltransferase (GlnE), Escherichia coli uridylyl
                     transferase (GlnD), and similar proteins; Region:
                     NT_GlnE_GlnD_like; cd05401"
                     /db_xref="CDD:143391"
     misc_feature    complement(order(188252..188254,188330..188332,
                     188336..188338))
                     /gene="glnD"
                     /locus_tag="b0167"
                     /gene_synonym="ECK0165; JW0162"
                     /note="metal binding triad; metal-binding site"
                     /db_xref="CDD:143391"
     misc_feature    complement(187658..188077)
                     /gene="glnD"
                     /locus_tag="b0167"
                     /gene_synonym="ECK0165; JW0162"
                     /note="GlnD PII-uridylyltransferase; Region:
                     GlnD_UR_UTase; pfam08335"
                     /db_xref="CDD:254738"
     misc_feature    complement(186797..187255)
                     /gene="glnD"
                     /locus_tag="b0167"
                     /gene_synonym="ECK0165; JW0162"
                     /note="Metal dependent phosphohydrolases with conserved
                     'HD' motif; Region: HDc; cd00077"
                     /db_xref="CDD:238032"
     misc_feature    complement(order(186860..186862,187106..187111,
                     187238..187240))
                     /gene="glnD"
                     /locus_tag="b0167"
                     /gene_synonym="ECK0165; JW0162"
                     /note="Zn2+ binding site [ion binding]; other site"
                     /db_xref="CDD:238032"
     misc_feature    complement(187106..187108)
                     /gene="glnD"
                     /locus_tag="b0167"
                     /gene_synonym="ECK0165; JW0162"
                     /note="Mg2+ binding site [ion binding]; other site"
                     /db_xref="CDD:238032"
     misc_feature    complement(186317..186532)
                     /gene="glnD"
                     /locus_tag="b0167"
                     /gene_synonym="ECK0165; JW0162"
                     /note="ACT domain family, ACT_UUR-like_1, includes the
                     first of two C-terminal ACT domains of the bacterial
                     signal-transducing uridylyltransferase /uridylyl-removing
                     (UUR) enzyme, GlnD and related domains; Region:
                     ACT_UUR-like_1; cd04900"
                     /db_xref="CDD:153172"
     misc_feature    complement(185999..186202)
                     /gene="glnD"
                     /locus_tag="b0167"
                     /gene_synonym="ECK0165; JW0162"
                     /note="C-terminal ACT domains of the bacterial
                     signal-transducing uridylyltransferase /uridylyl-removing
                     (UUR) enzyme, GlnD and related domains; Region:
                     ACT_ACR-UUR-like_2; cd04899"
                     /db_xref="CDD:153171"
     gene            complement(188712..189506)
                     /gene="map"
                     /locus_tag="b0168"
                     /gene_synonym="ECK0166; JW0163; pepM"
                     /db_xref="EcoGene:EG10570"
                     /db_xref="GeneID:947882"
     CDS             complement(188712..189506)
                     /gene="map"
                     /locus_tag="b0168"
                     /gene_synonym="ECK0166; JW0163; pepM"
                     /EC_number="3.4.11.18"
                     /function="enzyme; Proteins - translation and
                     modification"
                     /GO_process="GO:0006457 - protein folding"
                     /codon_start=1
                     /transl_table=11
                     /product="methionine aminopeptidase"
                     /protein_id="NP_414710.1"
                     /db_xref="GI:16128161"
                     /db_xref="ASAP:ABE-0000571"
                     /db_xref="UniProtKB/Swiss-Prot:P0AE18"
                     /db_xref="EcoGene:EG10570"
                     /db_xref="GeneID:947882"
                     /translation="MAISIKTPEDIEKMRVAGRLAAEVLEMIEPYVKPGVSTGELDRI
                     CNDYIVNEQHAVSACLGYHGYPKSVCISINEVVCHGIPDDAKLLKDGDIVNIDVTVIK
                     DGFHGDTSKMFIVGKPTIMGERLCRITQESLYLALRMVKPGINLREIGAAIQKFVEAE
                     GFSVVREYCGHGIGRGFHEEPQVLHYDSRETNVVLKPGMTFTIEPMVNAGKKEIRTMK
                     DGWTVKTKDRSLSAQYEHTIVVTDNGCEILTLRKDDTIPAIISHDE"
     misc_feature    complement(188757..189476)
                     /gene="map"
                     /locus_tag="b0168"
                     /gene_synonym="ECK0166; JW0163; pepM"
                     /note="Methionine Aminopeptidase 1. E.C. 3.4.11.18. Also
                     known as methionyl aminopeptidase and Peptidase M.
                     Catalyzes release of N-terminal amino acids,
                     preferentially methionine, from peptides and arylamides;
                     Region: MetAP1; cd01086"
                     /db_xref="CDD:238519"
     misc_feature    complement(order(188802..188804,188895..188897,
                     188994..188996,189183..189185,189216..189218,
                     189270..189272))
                     /gene="map"
                     /locus_tag="b0168"
                     /gene_synonym="ECK0166; JW0163; pepM"
                     /note="active site"
                     /db_xref="CDD:238519"
     gene            189712..189847
                     /gene="tff"
                     /locus_tag="b4414"
                     /gene_synonym="ECK0167; JWR0225; t44"
                     /db_xref="EcoGene:EG31135"
                     /db_xref="GeneID:2847773"
     ncRNA           189712..189847
                     /gene="tff"
                     /locus_tag="b4414"
                     /gene_synonym="ECK0167; JWR0225; t44"
                     /ncRNA_class="other"
                     /product="novel sRNA, function unknown"
                     /note="identified in a large scale screen"
                     /db_xref="ASAP:ABE-0047239"
                     /db_xref="EcoGene:EG31135"
                     /db_xref="GeneID:2847773"
     gene            189874..190599
                     /gene="rpsB"
                     /locus_tag="b0169"
                     /gene_synonym="ECK0168; JW0164"
                     /db_xref="EcoGene:EG10901"
                     /db_xref="GeneID:947874"
     CDS             189874..190599
                     /gene="rpsB"
                     /locus_tag="b0169"
                     /gene_synonym="ECK0168; JW0164"
                     /function="structural component; Ribosomal proteins -
                     synthesis, modification"
                     /GO_component="GO:0005737 - cytoplasm"
                     /GO_function="GO:0003735 - structural constituent of
                     ribosome"
                     /GO_process="GO:0006412 - translation"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal subunit protein S2"
                     /protein_id="NP_414711.1"
                     /db_xref="GI:16128162"
                     /db_xref="ASAP:ABE-0000575"
                     /db_xref="UniProtKB/Swiss-Prot:P0A7V0"
                     /db_xref="EcoGene:EG10901"
                     /db_xref="GeneID:947874"
                     /translation="MATVSMRDMLKAGVHFGHQTRYWNPKMKPFIFGARNKVHIINLE
                     KTVPMFNEALAELNKIASRKGKILFVGTKRAASEAVKDAALSCDQFFVNHRWLGGMLT
                     NWKTVRQSIKRLKDLETQSQDGTFDKLTKKEALMRTRELEKLENSLGGIKDMGGLPDA
                     LFVIDADHEHIAIKEANNLGIPVFAIVDTNSDPDGVDFVIPGNDDAIRAVTLYLGAVA
                     ATVREGRSQDLASQAEESFVEAE"
     misc_feature    189898..190542
                     /gene="rpsB"
                     /locus_tag="b0169"
                     /gene_synonym="ECK0168; JW0164"
                     /note="Ribosomal protein S2 (RPS2), involved in formation
                     of the translation initiation complex, where it might
                     contact the messenger RNA and several components of the
                     ribosome. It has been shown that in Escherichia coli RPS2
                     is essential for the binding of...; Region: RPS2; cd01425"
                     /db_xref="CDD:100106"
     misc_feature    order(189946..189951,189976..189984,190156..190158,
                     190162..190170,190177..190182,190396..190398,
                     190405..190407)
                     /gene="rpsB"
                     /locus_tag="b0169"
                     /gene_synonym="ECK0168; JW0164"
                     /note="rRNA interaction site [nucleotide binding]; other
                     site"
                     /db_xref="CDD:100106"
     misc_feature    order(190402..190407,190411..190413,190453..190464)
                     /gene="rpsB"
                     /locus_tag="b0169"
                     /gene_synonym="ECK0168; JW0164"
                     /note="S8 interaction site; other site"
                     /db_xref="CDD:100106"
     misc_feature    190507..190524
                     /gene="rpsB"
                     /locus_tag="b0169"
                     /gene_synonym="ECK0168; JW0164"
                     /note="putative laminin-1 binding site; other site"
                     /db_xref="CDD:100106"
     gene            190857..191708
                     /gene="tsf"
                     /locus_tag="b0170"
                     /gene_synonym="ECK0169; JW0165"
                     /db_xref="EcoGene:EG11033"
                     /db_xref="GeneID:944866"
     CDS             190857..191708
                     /gene="tsf"
                     /locus_tag="b0170"
                     /gene_synonym="ECK0169; JW0165"
                     /function="factor; Proteins - translation and
                     modification"
                     /GO_component="GO:0005737 - cytoplasm"
                     /GO_process="GO:0006412 - translation"
                     /codon_start=1
                     /transl_table=11
                     /product="translation elongation factor EF-Ts"
                     /protein_id="NP_414712.1"
                     /db_xref="GI:16128163"
                     /db_xref="ASAP:ABE-0000579"
                     /db_xref="UniProtKB/Swiss-Prot:P0A6P1"
                     /db_xref="EcoGene:EG11033"
                     /db_xref="GeneID:944866"
                     /translation="MAEITASLVKELRERTGAGMMDCKKALTEANGDIELAIENMRKS
                     GAIKAAKKAGNVAADGVIKTKIDGNYGIILEVNCQTDFVAKDAGFQAFADKVLDAAVA
                     GKITDVEVLKAQFEEERVALVAKIGENINIRRVAALEGDVLGSYQHGARIGVLVAAKG
                     ADEELVKHIAMHVAASKPEFIKPEDVSAEVVEKEYQVQLDIAMQSGKPKEIAEKMVEG
                     RMKKFTGEVSLTGQPFVMEPSKTVGQLLKEHNAEVTGFIRFEVGEGIEKVETDFAAEV
                     AAMSKQS"
     misc_feature    190857..191699
                     /gene="tsf"
                     /locus_tag="b0170"
                     /gene_synonym="ECK0169; JW0165"
                     /note="elongation factor Ts; Provisional; Region: tsf;
                     PRK09377"
                     /db_xref="CDD:236491"
     misc_feature    190866..190973
                     /gene="tsf"
                     /locus_tag="b0170"
                     /gene_synonym="ECK0169; JW0165"
                     /note="UBA/TS-N domain; Region: UBA; pfam00627"
                     /db_xref="CDD:250010"
     misc_feature    <191169..>191294
                     /gene="tsf"
                     /locus_tag="b0170"
                     /gene_synonym="ECK0169; JW0165"
                     /note="Bacterial virulence factor haemolysin; Region:
                     SMP_2; cl11479"
                     /db_xref="CDD:264392"
     gene            191855..192580
                     /gene="pyrH"
                     /locus_tag="b0171"
                     /gene_synonym="ECK0170; JW0166; smbA; umk"
                     /db_xref="EcoGene:EG11539"
                     /db_xref="GeneID:944989"
     CDS             191855..192580
                     /gene="pyrH"
                     /locus_tag="b0171"
                     /gene_synonym="ECK0170; JW0166; smbA; umk"
                     /EC_number="2.7.4.-"
                     /function="enzyme; Central intermediary metabolism:
                     Nucleotide interconversions"
                     /GO_component="GO:0005737 - cytoplasm"
                     /GO_process="GO:0015949 - nucleobase, nucleoside and
                     nucleotide interconversion"
                     /codon_start=1
                     /transl_table=11
                     /product="uridylate kinase"
                     /protein_id="NP_414713.1"
                     /db_xref="GI:16128164"
                     /db_xref="ASAP:ABE-0000582"
                     /db_xref="UniProtKB/Swiss-Prot:P0A7E9"
                     /db_xref="EcoGene:EG11539"
                     /db_xref="GeneID:944989"
                     /translation="MATNAKPVYKRILLKLSGEALQGTEGFGIDASILDRMAQEIKEL
                     VELGIQVGVVIGGGNLFRGAGLAKAGMNRVVGDHMGMLATVMNGLAMRDALHRAYVNA
                     RLMSAIPLNGVCDSYSWAEAISLLRNNRVVILSAGTGNPFFTTDSAACLRGIEIEADV
                     VLKATKVDGVFTADPAKDPTATMYEQLTYSEVLEKELKVMDLAAFTLARDHKLPIRVF
                     NMNKPGALRRVVMGEKEGTLITE"
     misc_feature    191882..192574
                     /gene="pyrH"
                     /locus_tag="b0171"
                     /gene_synonym="ECK0170; JW0166; smbA; umk"
                     /note="UMP kinase (UMPK)-Ec, the microbial/chloroplast
                     uridine monophosphate kinase (uridylate kinase) enzyme
                     that catalyzes UMP phosphorylation and plays a key role in
                     pyrimidine nucleotide biosynthesis; regulation of this
                     process is via feed-back control and...; Region:
                     AAK_UMPK-PyrH-Ec; cd04254"
                     /db_xref="CDD:239787"
     misc_feature    order(191897..191899,191906..191911,192020..192028,
                     192287..192292,192347..192352,192359..192361,
                     192365..192367,192371..192376)
                     /gene="pyrH"
                     /locus_tag="b0171"
                     /gene_synonym="ECK0170; JW0166; smbA; umk"
                     /note="putative nucleotide binding site [chemical
                     binding]; other site"
                     /db_xref="CDD:239787"
     misc_feature    order(192020..192028,192038..192043,192083..192085,
                     192092..192097,192266..192268,192272..192277,
                     192281..192289)
                     /gene="pyrH"
                     /locus_tag="b0171"
                     /gene_synonym="ECK0170; JW0166; smbA; umk"
                     /note="uridine monophosphate binding site [chemical
                     binding]; other site"
                     /db_xref="CDD:239787"
     misc_feature    order(192059..192064,192086..192091,192110..192112,
                     192131..192133,192161..192163,192203..192205,
                     192215..192217,192224..192226,192242..192244,
                     192266..192268,192272..192280,192305..192307,
                     192314..192319,192485..192487)
                     /gene="pyrH"
                     /locus_tag="b0171"
                     /gene_synonym="ECK0170; JW0166; smbA; umk"
                     /note="homohexameric interface [polypeptide binding];
                     other site"
                     /db_xref="CDD:239787"
     gene            192872..193429
                     /gene="frr"
                     /locus_tag="b0172"
                     /gene_synonym="ECK0171; JW0167; rrf"
                     /db_xref="EcoGene:EG10335"
                     /db_xref="GeneID:946122"
     CDS             192872..193429
                     /gene="frr"
                     /locus_tag="b0172"
                     /gene_synonym="ECK0171; JW0167; rrf"
                     /function="factor; Proteins - translation and
                     modification"
                     /experiment="N-terminus verified by Edman degradation:
                     PMID 2684966,8740179,9298646"
                     /GO_component="GO:0005737 - cytoplasm"
                     /GO_process="GO:0006412 - translation"
                     /GO_process="GO:0009386 - translational attenuation"
                     /note="ribosome releasing factor"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome recycling factor"
                     /protein_id="NP_414714.1"
                     /db_xref="GI:16128165"
                     /db_xref="ASAP:ABE-0000588"
                     /db_xref="UniProtKB/Swiss-Prot:P0A805"
                     /db_xref="EcoGene:EG10335"
                     /db_xref="GeneID:946122"
                     /translation="MISDIRKDAEVRMDKCVEAFKTQISKIRTGRASPSLLDGIVVEY
                     YGTPTPLRQLASVTVEDSRTLKINVFDRSMSPAVEKAIMASDLGLNPNSAGSDIRVPL
                     PPLTEERRKDLTKIVRGEAEQARVAVRNVRRDANDKVKALLKDKEISEDDDRRSQDDV
                     QKLTDAAIKKIEAALADKEAELMQF"
     misc_feature    192884..193420
                     /gene="frr"
                     /locus_tag="b0172"
                     /gene_synonym="ECK0171; JW0167; rrf"
                     /note="Ribosome recycling factor (RRF). Ribosome recycling
                     factor dissociates the posttermination complex, composed
                     of the ribosome, deacylated tRNA, and mRNA, after
                     termination of translation.  Thus ribosomes are 'recycled'
                     and ready for another...; Region: RRF; cd00520"
                     /db_xref="CDD:238288"
     misc_feature    order(192956..192967,193175..193186)
                     /gene="frr"
                     /locus_tag="b0172"
                     /gene_synonym="ECK0171; JW0167; rrf"
                     /note="hinge region; other site"
                     /db_xref="CDD:238288"
     gene            193521..194717
                     /gene="dxr"
                     /locus_tag="b0173"
                     /gene_synonym="ECK0172; ispC; JW0168; yaeM"
                     /db_xref="EcoGene:EG12715"
                     /db_xref="GeneID:945019"
     CDS             193521..194717
                     /gene="dxr"
                     /locus_tag="b0173"
                     /gene_synonym="ECK0172; ispC; JW0168; yaeM"
                     /EC_number="1.1.1.267"
                     /function="putative transport; Not classified"
                     /codon_start=1
                     /transl_table=11
                     /product="1-deoxy-D-xylulose 5-phosphate reductoisomerase"
                     /protein_id="NP_414715.1"
                     /db_xref="GI:16128166"
                     /db_xref="ASAP:ABE-0000592"
                     /db_xref="UniProtKB/Swiss-Prot:P45568"
                     /db_xref="EcoGene:EG12715"
                     /db_xref="GeneID:945019"
                     /translation="MKQLTILGSTGSIGCSTLDVVRHNPEHFRVVALVAGKNVTRMVE
                     QCLEFSPRYAVMDDEASAKLLKTMLQQQGSRTEVLSGQQAACDMAALEDVDQVMAAIV
                     GAAGLLPTLAAIRAGKTILLANKESLVTCGRLFMDAVKQSKAQLLPVDSEHNAIFQSL
                     PQPIQHNLGYADLEQNGVVSILLTGSGGPFRETPLRDLATMTPDQACRHPNWSMGRKI
                     SVDSATMMNKGLEYIEARWLFNASASQMEVLIHPQSVIHSMVRYQDGSVLAQLGEPDM
                     RTPIAHTMAWPNRVNSGVKPLDFCKLSALTFAAPDYDRYPCLKLAMEAFEQGQAATTA
                     LNAANEITVAAFLAQQIRFTDIAALNLSVLEKMDMREPQCVDDVLSVDANAREVARKE
                     VMRLAS"
     misc_feature    193521..194714
                     /gene="dxr"
                     /locus_tag="b0173"
                     /gene_synonym="ECK0172; ispC; JW0168; yaeM"
                     /note="1-deoxy-D-xylulose 5-phosphate reductoisomerase;
                     Region: Dxr; TIGR00243"
                     /db_xref="CDD:161787"
     misc_feature    193530..193916
                     /gene="dxr"
                     /locus_tag="b0173"
                     /gene_synonym="ECK0172; ispC; JW0168; yaeM"
                     /note="1-deoxy-D-xylulose 5-phosphate reductoisomerase;
                     Region: DXP_reductoisom; pfam02670"
                     /db_xref="CDD:251461"
     misc_feature    193956..194237
                     /gene="dxr"
                     /locus_tag="b0173"
                     /gene_synonym="ECK0172; ispC; JW0168; yaeM"
                     /note="1-deoxy-D-xylulose 5-phosphate reductoisomerase
                     C-terminal; Region: DXP_redisom_C; pfam08436"
                     /db_xref="CDD:254800"
     misc_feature    194331..194687
                     /gene="dxr"
                     /locus_tag="b0173"
                     /gene_synonym="ECK0172; ispC; JW0168; yaeM"
                     /note="DXP reductoisomerase C-terminal domain; Region:
                     DXPR_C; pfam13288"
                     /db_xref="CDD:257629"
     gene            194903..195664
                     /gene="ispU"
                     /locus_tag="b0174"
                     /gene_synonym="ECK0173; JW0169; rth; uppS; yaeS"
                     /db_xref="EcoGene:EG13329"
                     /db_xref="GeneID:944874"
     CDS             194903..195664
                     /gene="ispU"
                     /locus_tag="b0174"
                     /gene_synonym="ECK0173; JW0169; rth; uppS; yaeS"
                     /EC_number="2.5.1.31"
                     /experiment="N-terminus verified by Edman degradation:
                     PMID 9882662"
                     /GO_component="GO:0005737 - cytoplasm"
                     /GO_function="GO:0042280 - cell surface antigen activity,
                     host-interacting"
                     /note="undecaprenyl pyrophosphate synthetase
                     (di-trans,poly-cis-decaprenylcistransferase)"
                     /codon_start=1
                     /transl_table=11
                     /product="undecaprenyl pyrophosphate synthase"
                     /protein_id="NP_414716.1"
                     /db_xref="GI:16128167"
                     /db_xref="ASAP:ABE-0000595"
                     /db_xref="UniProtKB/Swiss-Prot:P60472"
                     /db_xref="EcoGene:EG13329"
                     /db_xref="GeneID:944874"
                     /translation="MMLSATQPLSEKLPAHGCRHVAIIMDGNGRWAKKQGKIRAFGHK
                     AGAKSVRRAVSFAANNGIEALTLYAFSSENWNRPAQEVSALMELFVWALDSEVKSLHR
                     HNVRLRIIGDTSRFNSRLQERIRKSEALTAGNTGLTLNIAANYGGRWDIVQGVRQLAE
                     KVQQGNLQPDQIDEEMLNQHVCMHELAPVDLVIRTGGEHRISNFLLWQIAYAELYFTD
                     VLWPDFDEQDFEGALNAFANRERRFGGTEPGDETA"
     misc_feature    194960..195616
                     /gene="ispU"
                     /locus_tag="b0174"
                     /gene_synonym="ECK0173; JW0169; rth; uppS; yaeS"
                     /note="Cis (Z)-Isoprenyl Diphosphate Synthases; Region:
                     Cis_IPPS; cd00475"
                     /db_xref="CDD:259850"
     misc_feature    order(194975..194992,195017..195019,195029..195031,
                     195041..195043,195050..195052,195107..195109,
                     195131..195133,195143..195145,195164..195169,
                     195176..195178,195323..195325,195482..195484,
                     195500..195502,195506..195508)
                     /gene="ispU"
                     /locus_tag="b0174"
                     /gene_synonym="ECK0173; JW0169; rth; uppS; yaeS"
                     /note="active site"
                     /db_xref="CDD:259850"
     misc_feature    order(195344..195349,195353..195358,195365..195370,
                     195416..195424,195431..195433,195464..195466,
                     195497..195511,195518..195526,195530..195544,
                     195548..195550)
                     /gene="ispU"
                     /locus_tag="b0174"
                     /gene_synonym="ECK0173; JW0169; rth; uppS; yaeS"
                     /note="dimer interface [polypeptide binding]; other site"
                     /db_xref="CDD:259850"
     gene            195677..196534
                     /gene="cdsA"
                     /locus_tag="b0175"
                     /gene_synonym="ECK0174; JW5810"
                     /db_xref="EcoGene:EG10139"
                     /db_xref="GeneID:944876"
     CDS             195677..196534
                     /gene="cdsA"
                     /locus_tag="b0175"
                     /gene_synonym="ECK0174; JW5810"
                     /EC_number="2.7.7.41"
                     /function="enzyme; Fatty acid and phosphatidic acid
                     biosynthesis"
                     /GO_component="GO:0009274 - peptidoglycan-based cell wall"
                     /GO_component="GO:0019866 - organelle inner membrane"
                     /GO_process="GO:0008654 - phospholipid biosynthetic
                     process"
                     /note="CDP-diglyceride synthetase"
                     /codon_start=1
                     /transl_table=11
                     /product="CDP-diglyceride synthase"
                     /protein_id="NP_414717.2"
                     /db_xref="GI:90111095"
                     /db_xref="ASAP:ABE-0000600"
                     /db_xref="UniProtKB/Swiss-Prot:P0ABG1"
                     /db_xref="EcoGene:EG10139"
                     /db_xref="GeneID:944876"
                     /translation="MLKYRLISAFVLIPVVIAALFLLPPVGFAIVTLVVCMLAAWEWG
                     QLSGFTTRSQRVWLAVLCGLLLALMLFLLPEYHRNIHQPLVEISLWASLGWWIVALLL
                     VLFYPGSAAIWRNSKTLRLIFGVLTIVPFFWGMLALRAWHYDENHYSGAIWLLYVMIL
                     VWGADSGAYMFGKLFGKHKLAPKVSPGKTWQGFIGGLATAAVISWGYGMWANLDVAPV
                     TLLICSIVAALASVLGDLTESMFKREAGIKDSGHLIPGHGGILDRIDSLTAAVPVFAC
                     LLLLVFRTL"
     misc_feature    195677..196531
                     /gene="cdsA"
                     /locus_tag="b0175"
                     /gene_synonym="ECK0174; JW5810"
                     /note="CDP-diglyceride synthase; Provisional; Region:
                     cdsA; PRK11624"
                     /db_xref="CDD:183240"
     gene            196546..197898
                     /gene="rseP"
                     /locus_tag="b0176"
                     /gene_synonym="ecfE; ECK0175; JW0171; yaeL"
                     /db_xref="EcoGene:EG12436"
                     /db_xref="GeneID:944871"
     CDS             196546..197898
                     /gene="rseP"
                     /locus_tag="b0176"
                     /gene_synonym="ecfE; ECK0175; JW0171; yaeL"
                     /EC_number="3.4.24.-"
                     /codon_start=1
                     /transl_table=11
                     /product="inner membrane zinc RIP metalloprotease; RpoE
                     activator, by degrading RseA; cleaved signal peptide
                     endoprotease"
                     /protein_id="NP_414718.1"
                     /db_xref="GI:16128169"
                     /db_xref="ASAP:ABE-0000603"
                     /db_xref="UniProtKB/Swiss-Prot:P0AEH1"
                     /db_xref="EcoGene:EG12436"
                     /db_xref="GeneID:944871"
                     /translation="MLSFLWDLASFIVALGVLITVHEFGHFWVARRCGVRVERFSIGF
                     GKALWRRTDKLGTEYVIALIPLGGYVKMLDERAEPVVPELRHHAFNNKSVGQRAAIIA
                     AGPVANFIFAIFAYWLVFIIGVPGVRPVVGEIAANSIAAEAQIAPGTELKAVDGIETP
                     DWDAVRLQLVDKIGDESTTITVAPFGSDQRRDVKLDLRHWAFEPDKEDPVSSLGIRPR
                     GPQIEPVLENVQPNSAASKAGLQAGDRIVKVDGQPLTQWVTFVMLVRDNPGKSLALEI
                     ERQGSPLSLTLIPESKPGNGKAIGFVGIEPKVIPLPDEYKVVRQYGPFNAIVEATDKT
                     WQLMKLTVSMLGKLITGDVKLNNLSGPISIAKGAGMTAELGVVYYLPFLALISVNLGI
                     INLFPLPVLDGGHLLFLAIEKIKGGPVSERVQDFCYRIGSILLVLLMGLALFNDFSRL
                     "
     misc_feature    196549..197895
                     /gene="rseP"
                     /locus_tag="b0176"
                     /gene_synonym="ecfE; ECK0175; JW0171; yaeL"
                     /note="zinc metallopeptidase RseP; Provisional; Region:
                     PRK10779"
                     /db_xref="CDD:182723"
     misc_feature    196567..>196905
                     /gene="rseP"
                     /locus_tag="b0176"
                     /gene_synonym="ecfE; ECK0175; JW0171; yaeL"
                     /note="RseP-like Site-2 proteases (S2P), zinc
                     metalloproteases (MEROPS family M50A), cleave
                     transmembrane domains of substrate proteins, regulating
                     intramembrane proteolysis (RIP) of diverse signal
                     transduction mechanisms. In Escherichia coli, the S2P
                     homolog...; Region: S2P-M50_PDZ_RseP-like; cd06163"
                     /db_xref="CDD:100084"
     misc_feature    order(196609..196614,196621..196623)
                     /gene="rseP"
                     /locus_tag="b0176"
                     /gene_synonym="ecfE; ECK0175; JW0171; yaeL"
                     /note="active site"
                     /db_xref="CDD:100084"
     misc_feature    196891..197130
                     /gene="rseP"
                     /locus_tag="b0176"
                     /gene_synonym="ecfE; ECK0175; JW0171; yaeL"
                     /note="PDZ domain of bacterial and plant zinc
                     metalloprotases, presumably membrane-associated or
                     integral membrane proteases, which may be involved in
                     signalling and regulatory mechanisms. May be responsible
                     for substrate recognition and/or binding, as most PDZ...;
                     Region: PDZ_metalloprotease; cd00989"
                     /db_xref="CDD:238489"
     misc_feature    order(196894..196905,196909..196911,197038..197043,
                     197050..197055)
                     /gene="rseP"
                     /locus_tag="b0176"
                     /gene_synonym="ecfE; ECK0175; JW0171; yaeL"
                     /note="protein binding site [polypeptide binding]; other
                     site"
                     /db_xref="CDD:238489"
     misc_feature    197176..197412
                     /gene="rseP"
                     /locus_tag="b0176"
                     /gene_synonym="ecfE; ECK0175; JW0171; yaeL"
                     /note="PDZ domain of bacterial and plant zinc
                     metalloprotases, presumably membrane-associated or
                     integral membrane proteases, which may be involved in
                     signalling and regulatory mechanisms. May be responsible
                     for substrate recognition and/or binding, as most PDZ...;
                     Region: PDZ_metalloprotease; cd00989"
                     /db_xref="CDD:238489"
     misc_feature    order(197179..197190,197194..197196,197323..197328,
                     197335..197340)
                     /gene="rseP"
                     /locus_tag="b0176"
                     /gene_synonym="ecfE; ECK0175; JW0171; yaeL"
                     /note="protein binding site [polypeptide binding]; other
                     site"
                     /db_xref="CDD:238489"
     misc_feature    <197683..197892
                     /gene="rseP"
                     /locus_tag="b0176"
                     /gene_synonym="ecfE; ECK0175; JW0171; yaeL"
                     /note="Site-2 protease (S2P) class of zinc
                     metalloproteases (MEROPS family M50) cleaves transmembrane
                     domains of substrate proteins, regulating intramembrane
                     proteolysis (RIP) of diverse signal transduction
                     mechanisms. Members of this family use proteolytic...;
                     Region: S2P-M50; cl10020"
                     /db_xref="CDD:245232"
     misc_feature    197725..197736
                     /gene="rseP"
                     /locus_tag="b0176"
                     /gene_synonym="ecfE; ECK0175; JW0171; yaeL"
                     /note="putative substrate binding region [chemical
                     binding]; other site"
                     /db_xref="CDD:100078"
     gene            197928..200360
                     /gene="bamA"
                     /locus_tag="b0177"
                     /gene_synonym="ecfK; ECK0176; JW0172; omp85; yaeT; yzzN;
                     yzzY"
                     /db_xref="EcoGene:EG12676"
                     /db_xref="GeneID:944870"
     CDS             197928..200360
                     /gene="bamA"
                     /locus_tag="b0177"
                     /gene_synonym="ecfK; ECK0176; JW0172; omp85; yaeT; yzzN;
                     yzzY"
                     /GO_component="GO:0009274 - peptidoglycan-based cell wall"
                     /GO_component="GO:0009279 - cell outer membrane"
                     /note="putative outer membrane antigen"
                     /codon_start=1
                     /transl_table=11
                     /product="BamABCDE complex OM biogenesis outer membrane
                     pore-forming assembly factor"
                     /protein_id="NP_414719.1"
                     /db_xref="GI:16128170"
                     /db_xref="ASAP:ABE-0000605"
                     /db_xref="UniProtKB/Swiss-Prot:P0A940"
                     /db_xref="EcoGene:EG12676"
                     /db_xref="GeneID:944870"
                     /translation="MAMKKLLIASLLFSSATVYGAEGFVVKDIHFEGLQRVAVGAALL
                     SMPVRTGDTVNDEDISNTIRALFATGNFEDVRVLRDGDTLLVQVKERPTIASITFSGN
                     KSVKDDMLKQNLEASGVRVGESLDRTTIADIEKGLEDFYYSVGKYSASVKAVVTPLPR
                     NRVDLKLVFQEGVSAEIQQINIVGNHAFTTDELISHFQLRDEVPWWNVVGDRKYQKQK
                     LAGDLETLRSYYLDRGYARFNIDSTQVSLTPDKKGIYVTVNITEGDQYKLSGVEVSGN
                     LAGHSAEIEQLTKIEPGELYNGTKVTKMEDDIKKLLGRYGYAYPRVQSMPEINDADKT
                     VKLRVNVDAGNRFYVRKIRFEGNDTSKDAVLRREMRQMEGAWLGSDLVDQGKERLNRL
                     GFFETVDTDTQRVPGSPDQVDVVYKVKERNTGSFNFGIGYGTESGVSFQAGVQQDNWL
                     GTGYAVGINGTKNDYQTYAELSVTNPYFTVDGVSLGGRLFYNDFQADDADLSDYTNKS
                     YGTDVTLGFPINEYNSLRAGLGYVHNSLSNMQPQVAMWRYLYSMGEHPSTSDQDNSFK
                     TDDFTFNYGWTYNKLDRGYFPTDGSRVNLTGKVTIPGSDNEYYKVTLDTATYVPIDDD
                     HKWVVLGRTRWGYGDGLGGKEMPFYENFYAGGSSTVRGFQSNTIGPKAVYFPHQASNY
                     DPDYDYECATQDGAKDLCKSDDAVGGNAMAVASLEFITPTPFISDKYANSVRTSFFWD
                     MGTVWDTNWDSSQYSGYPDYSDPSNIRMSAGIALQWMSPLGPLVFSYAQPFKKYDGDK
                     AEQFQFNIGKTW"
     misc_feature    197928..200357
                     /gene="bamA"
                     /locus_tag="b0177"
                     /gene_synonym="ecfK; ECK0176; JW0172; omp85; yaeT; yzzN;
                     yzzY"
                     /note="outer membrane protein assembly factor YaeT;
                     Provisional; Region: PRK11067"
                     /db_xref="CDD:236834"
     misc_feature    197997..198200
                     /gene="bamA"
                     /locus_tag="b0177"
                     /gene_synonym="ecfK; ECK0176; JW0172; omp85; yaeT; yzzN;
                     yzzY"
                     /note="Surface antigen variable number repeat; Region:
                     Surf_Ag_VNR; pfam07244"
                     /db_xref="CDD:254121"
     misc_feature    198201..198443
                     /gene="bamA"
                     /locus_tag="b0177"
                     /gene_synonym="ecfK; ECK0176; JW0172; omp85; yaeT; yzzN;
                     yzzY"
                     /note="Surface antigen variable number repeat; Region:
                     Surf_Ag_VNR; pfam07244"
                     /db_xref="CDD:254121"
     misc_feature    198450..198716
                     /gene="bamA"
                     /locus_tag="b0177"
                     /gene_synonym="ecfK; ECK0176; JW0172; omp85; yaeT; yzzN;
                     yzzY"
                     /note="Surface antigen variable number repeat; Region:
                     Surf_Ag_VNR; pfam07244"
                     /db_xref="CDD:254121"
     misc_feature    198723..198959
                     /gene="bamA"
                     /locus_tag="b0177"
                     /gene_synonym="ecfK; ECK0176; JW0172; omp85; yaeT; yzzN;
                     yzzY"
                     /note="Surface antigen variable number repeat; Region:
                     Surf_Ag_VNR; pfam07244"
                     /db_xref="CDD:254121"
     misc_feature    198966..199190
                     /gene="bamA"
                     /locus_tag="b0177"
                     /gene_synonym="ecfK; ECK0176; JW0172; omp85; yaeT; yzzN;
                     yzzY"
                     /note="Surface antigen variable number repeat; Region:
                     Surf_Ag_VNR; pfam07244"
                     /db_xref="CDD:254121"
     misc_feature    199269..200357
                     /gene="bamA"
                     /locus_tag="b0177"
                     /gene_synonym="ecfK; ECK0176; JW0172; omp85; yaeT; yzzN;
                     yzzY"
                     /note="Surface antigen; Region: Bac_surface_Ag; pfam01103"
                     /db_xref="CDD:250364"
     gene            200482..200967
                     /gene="skp"
                     /locus_tag="b0178"
                     /gene_synonym="ECK0177; hlpA; JW0173; ompH"
                     /db_xref="EcoGene:EG10455"
                     /db_xref="GeneID:944861"
     CDS             200482..200967
                     /gene="skp"
                     /locus_tag="b0178"
                     /gene_synonym="ECK0177; hlpA; JW0173; ompH"
                     /function="factor; Basic proteins - synthesis,
                     modification"
                     /GO_component="GO:0009274 - peptidoglycan-based cell wall"
                     /GO_component="GO:0042597 - periplasmic space"
                     /GO_process="GO:0006457 - protein folding"
                     /note="periplasmic molecular chaperone for outer membrane
                     proteins"
                     /codon_start=1
                     /transl_table=11
                     /product="periplasmic chaperone"
                     /protein_id="NP_414720.1"
                     /db_xref="GI:16128171"
                     /db_xref="ASAP:ABE-0000608"
                     /db_xref="UniProtKB/Swiss-Prot:P0AEU7"
                     /db_xref="EcoGene:EG10455"
                     /db_xref="GeneID:944861"
                     /translation="MKKWLLAAGLGLALATSAQAADKIAIVNMGSLFQQVAQKTGVSN
                     TLENEFKGRASELQRMETDLQAKMKKLQSMKAGSDRTKLEKDVMAQRQTFAQKAQAFE
                     QDRARRSNEERGKLVTRIQTAVKSVANSQDIDLVVDANAVAYNSSDVKDITADVLKQV
                     K"
     misc_feature    200482..200964
                     /gene="skp"
                     /locus_tag="b0178"
                     /gene_synonym="ECK0177; hlpA; JW0173; ompH"
                     /note="periplasmic chaperone; Provisional; Region:
                     PRK10780"
                     /db_xref="CDD:182724"
     gene            200971..201996
                     /gene="lpxD"
                     /locus_tag="b0179"
                     /gene_synonym="ECK0178; firA; JW0174; omsA; ssc"
                     /db_xref="EcoGene:EG10316"
                     /db_xref="GeneID:944882"
     CDS             200971..201996
                     /gene="lpxD"
                     /locus_tag="b0179"
                     /gene_synonym="ECK0178; firA; JW0174; omsA; ssc"
                     /EC_number="2.3.1.-"
                     /function="enzyme; Surface polysaccharides & antigens"
                     /GO_function="GO:0042280 - cell surface antigen activity,
                     host-interacting"
                     /GO_process="GO:0009245 - lipid A biosynthetic process"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-3-O-(3-hydroxymyristoyl)-glucosamine
                     N-acyltransferase"
                     /protein_id="NP_414721.1"
                     /db_xref="GI:16128172"
                     /db_xref="ASAP:ABE-0000610"
                     /db_xref="UniProtKB/Swiss-Prot:P21645"
                     /db_xref="EcoGene:EG10316"
                     /db_xref="GeneID:944882"
                     /translation="MPSIRLADLAQQLDAELHGDGDIVITGVASMQSAQTGHITFMVN
                     PKYREHLGLCQASAVVMTQDDLPFAKSAALVVKNPYLTYARMAQILDTTPQPAQNIAP
                     SAVIDATAKLGNNVSIGANAVIESGVELGDNVIIGAGCFVGKNSKIGAGSRLWANVTI
                     YHEIQIGQNCLIQSGTVVGADGFGYANDRGNWVKIPQIGRVIIGDRVEIGACTTIDRG
                     ALDDTIIGNGVIIDNQCQIAHNVVIGDNTAVAGGVIMAGSLKIGRYCMIGGASVINGH
                     MEICDKVTVTGMGMVMRPITEPGVYSSGIPLQPNKVWRKTAALVMNIDDMSKRLKSLE
                     RKVNQQD"
     misc_feature    200974..201990
                     /gene="lpxD"
                     /locus_tag="b0179"
                     /gene_synonym="ECK0178; firA; JW0174; omsA; ssc"
                     /note="UDP-3-O-[3-hydroxymyristoyl] glucosamine
                     N-acyltransferase; Provisional; Region: lpxD; PRK00892"
                     /db_xref="CDD:234858"
     misc_feature    201031..201240
                     /gene="lpxD"
                     /locus_tag="b0179"
                     /gene_synonym="ECK0178; firA; JW0174; omsA; ssc"
                     /note="UDP-3-O-[3-hydroxymyristoyl] glucosamine
                     N-acyltransferase, LpxD; Region: LpxD; pfam04613"
                     /db_xref="CDD:252703"
     misc_feature    201295..201912
                     /gene="lpxD"
                     /locus_tag="b0179"
                     /gene_synonym="ECK0178; firA; JW0174; omsA; ssc"
                     /note="UDP-3-O-acyl-glucosamine N-acyltransferase (LpxD):
                     The enzyme catalyzes the transfer of 3-hydroxymyristic
                     acid or 3-hydroxy-arachidic acid, depending on the
                     organism, from the acyl carrier protein (ACP) to
                     UDP-3-O-acyl-glucosamine to produce UDP-2; Region:
                     LbH_LpxD; cd03352"
                     /db_xref="CDD:100043"
     misc_feature    order(201331..201333,201343..201348,201400..201402,
                     201439..201441,201445..201447,201451..201453,
                     201487..201489,201493..201495,201511..201513,
                     201517..201519,201550..201558,201592..201594,
                     201604..201606,201610..201612,201616..201618,
                     201625..201633,201658..201660,201664..201672,
                     201676..201678,201688..201690,201706..201708,
                     201712..201714,201724..201732,201760..201762,
                     201778..201786,201796..201798,201832..201840,
                     201892..201894,201904..201906)
                     /gene="lpxD"
                     /locus_tag="b0179"
                     /gene_synonym="ECK0178; firA; JW0174; omsA; ssc"
                     /note="trimer interface [polypeptide binding]; other site"
                     /db_xref="CDD:100043"
     misc_feature    order(201517..201525,201664..201666,201676..201678,
                     201685..201690,201718..201723,201736..201744,
                     201793..201798,201829..201831)
                     /gene="lpxD"
                     /locus_tag="b0179"
                     /gene_synonym="ECK0178; firA; JW0174; omsA; ssc"
                     /note="active site"
                     /db_xref="CDD:100043"
     misc_feature    order(201517..201525,201685..201690,201739..201744,
                     201793..201798)
                     /gene="lpxD"
                     /locus_tag="b0179"
                     /gene_synonym="ECK0178; firA; JW0174; omsA; ssc"
                     /note="UDP-GlcNAc binding site [chemical binding]; other
                     site"
                     /db_xref="CDD:100043"
     misc_feature    order(201664..201666,201676..201678,201718..201723,
                     201736..201738,201829..201831)
                     /gene="lpxD"
                     /locus_tag="b0179"
                     /gene_synonym="ECK0178; firA; JW0174; omsA; ssc"
                     /note="lipid binding site [chemical binding];
                     lipid-binding site"
                     /db_xref="CDD:100043"
     gene            202101..202556
                     /gene="fabZ"
                     /locus_tag="b0180"
                     /gene_synonym="ECK0179; JW0175; sabA; sefA; sfhC; yaeA"
                     /db_xref="EcoGene:EG11284"
                     /db_xref="GeneID:944888"
     CDS             202101..202556
                     /gene="fabZ"
                     /locus_tag="b0180"
                     /gene_synonym="ECK0179; JW0175; sabA; sefA; sfhC; yaeA"
                     /EC_number="4.2.1.-"
                     /function="enzyme; Fatty acid and phosphatidic acid
                     biosynthesis"
                     /GO_component="GO:0005737 - cytoplasm"
                     /codon_start=1
                     /transl_table=11
                     /product="(3R)-hydroxymyristol acyl carrier protein
                     dehydratase"
                     /protein_id="NP_414722.1"
                     /db_xref="GI:16128173"
                     /db_xref="ASAP:ABE-0000613"
                     /db_xref="UniProtKB/Swiss-Prot:P0A6Q6"
                     /db_xref="EcoGene:EG11284"
                     /db_xref="GeneID:944888"
                     /translation="MTTNTHTLQIEEILELLPHRFPFLLVDRVLDFEEGRFLRAVKNV
                     SVNEPFFQGHFPGKPIFPGVLILEAMAQATGILAFKSVGKLEPGELYYFAGIDEARFK
                     RPVVPGDQMIMEVTFEKTRRGLTRFKGVALVDGKVVCEATMMCARSREA"
     misc_feature    202149..202538
                     /gene="fabZ"
                     /locus_tag="b0180"
                     /gene_synonym="ECK0179; JW0175; sabA; sefA; sfhC; yaeA"
                     /note="FabZ is a 17kD beta-hydroxyacyl-acyl carrier
                     protein (ACP) dehydratase that primarily catalyzes the
                     dehydration of beta-hydroxyacyl-ACP to trans-2-acyl-ACP,
                     the third step in the elongation phase of the bacterial/
                     plastid, type II, fatty-acid...; Region: FabZ; cd01288"
                     /db_xref="CDD:238615"
     gene            202560..203348
                     /gene="lpxA"
                     /locus_tag="b0181"
                     /gene_synonym="ECK0180; JW0176"
                     /db_xref="EcoGene:EG10545"
                     /db_xref="GeneID:944849"
     CDS             202560..203348
                     /gene="lpxA"
                     /locus_tag="b0181"
                     /gene_synonym="ECK0180; JW0176"
                     /EC_number="2.3.1.129"
                     /function="enzyme; Surface polysaccharides & antigens"
                     /experiment="N-terminus verified by Edman degradation:
                     PMID 8366124"
                     /GO_component="GO:0005737 - cytoplasm"
                     /GO_function="GO:0042280 - cell surface antigen activity,
                     host-interacting"
                     /GO_process="GO:0009245 - lipid A biosynthetic process"
                     /note="UDP-N-acetylglucosamine acetyltransferase; lipid A
                     biosynthesis"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine acetyltransferase"
                     /protein_id="NP_414723.1"
                     /db_xref="GI:16128174"
                     /db_xref="ASAP:ABE-0000618"
                     /db_xref="UniProtKB/Swiss-Prot:P0A722"
                     /db_xref="EcoGene:EG10545"
                     /db_xref="GeneID:944849"
                     /translation="MIDKSAFVHPTAIVEEGASIGANAHIGPFCIVGPHVEIGEGTVL
                     KSHVVVNGHTKIGRDNEIYQFASIGEVNQDLKYAGEPTRVEIGDRNRIRESVTIHRGT
                     VQGGGLTKVGSDNLLMINAHIAHDCTVGNRCILANNATLAGHVSVDDFAIIGGMTAVH
                     QFCIIGAHVMVGGCSGVAQDVPPYVIAQGNHATPFGVNIEGLKRRGFSREAITAIRNA
                     YKLIYRSGKTLDEVKPEIAELAETYPEVKAFTDFFARSTRGLIR"
     misc_feature    202569..203345
                     /gene="lpxA"
                     /locus_tag="b0181"
                     /gene_synonym="ECK0180; JW0176"
                     /note="UDP-N-acetylglucosamine acyltransferase;
                     Provisional; Region: PRK05289"
                     /db_xref="CDD:235390"
     misc_feature    202581..203339
                     /gene="lpxA"
                     /locus_tag="b0181"
                     /gene_synonym="ECK0180; JW0176"
                     /note="UDP-N-acetylglucosamine O-acyltransferase
                     (UDP-GlcNAc acyltransferase): Proteins in this family
                     catalyze the transfer of (R)-3-hydroxymyristic acid from
                     its acyl carrier protein thioester to UDP-GlcNAc. It is
                     the first enzyme in the lipid A biosynthetic...; Region:
                     LbH_UDP-GlcNAc_AT; cd03351"
                     /db_xref="CDD:100042"
     misc_feature    order(202776..202778,202785..202787,202854..202856,
                     202923..202925,202932..202934,202989..202991,
                     203037..203042,203076..203078,203151..203153,
                     203169..203174)
                     /gene="lpxA"
                     /locus_tag="b0181"
                     /gene_synonym="ECK0180; JW0176"
                     /note="active site"
                     /db_xref="CDD:100042"
     gene            203348..204496
                     /gene="lpxB"
                     /locus_tag="b0182"
                     /gene_synonym="ECK0181; JW0177; pgsB"
                     /db_xref="EcoGene:EG10546"
                     /db_xref="GeneID:944838"
     CDS             203348..204496
                     /gene="lpxB"
                     /locus_tag="b0182"
                     /gene_synonym="ECK0181; JW0177; pgsB"
                     /EC_number="2.4.1.182"
                     /function="enzyme; Macromolecule metabolism:
                     Lipopolysaccharide"
                     /experiment="N-terminus verified by Edman degradation:
                     PMID 3049593"
                     /GO_component="GO:0009274 - peptidoglycan-based cell wall"
                     /GO_component="GO:0005737 - cytoplasm"
                     /GO_function="GO:0042280 - cell surface antigen activity,
                     host-interacting"
                     /GO_process="GO:0009245 - lipid A biosynthetic process"
                     /note="tetraacyldisaccharide-1-P; lipid A biosynthesis,
                     penultimate step"
                     /codon_start=1
                     /transl_table=11
                     /product="tetraacyldisaccharide-1-P synthase"
                     /protein_id="NP_414724.1"
                     /db_xref="GI:16128175"
                     /db_xref="ASAP:ABE-0000620"
                     /db_xref="UniProtKB/Swiss-Prot:P10441"
                     /db_xref="EcoGene:EG10546"
                     /db_xref="GeneID:944838"
                     /translation="MTEQRPLTIALVAGETSGDILGAGLIRALKEHVPNARFVGVAGP
                     RMQAEGCEAWYEMEELAVMGIVEVLGRLRRLLHIRADLTKRFGELKPDVFVGIDAPDF
                     NITLEGNLKKQGIKTIHYVSPSVWAWRQKRVFKIGRATDLVLAFLPFEKAFYDKYNVP
                     CRFIGHTMADAMPLDPDKNAARDVLGIPHDAHCLALLPGSRGAEVEMLSADFLKTAQL
                     LRQTYPDLEIVVPLVNAKRREQFERIKAEVAPDLSVHLLDGMGREAMVASDAALLASG
                     TAALECMLAKCPMVVGYRMKPFTFWLAKRLVKTDYVSLPNLLAGRELVKELLQEECEP
                     QKLAAALLPLLANGKTSHAMHDTFRELHQQIRCNADEQAAQAVLELAQ"
     misc_feature    203363..204493
                     /gene="lpxB"
                     /locus_tag="b0182"
                     /gene_synonym="ECK0181; JW0177; pgsB"
                     /note="lipid-A-disaccharide synthase; Reviewed; Region:
                     lpxB; PRK00025"
                     /db_xref="CDD:234580"
     misc_feature    203369..204340
                     /gene="lpxB"
                     /locus_tag="b0182"
                     /gene_synonym="ECK0181; JW0177; pgsB"
                     /note="ipid-A-disaccharide synthase; Provisional; Region:
                     PRK14089"
                     /db_xref="CDD:237606"
     gene            204493..205089
                     /gene="rnhB"
                     /locus_tag="b0183"
                     /gene_synonym="ECK0182; JW0178"
                     /db_xref="EcoGene:EG10861"
                     /db_xref="GeneID:944852"
     CDS             204493..205089
                     /gene="rnhB"
                     /locus_tag="b0183"
                     /gene_synonym="ECK0182; JW0178"
                     /EC_number="3.1.26.4"
                     /function="enzyme; Degradation of RNA"
                     /experiment="N-terminus verified by Edman degradation:
                     PMID 2172991"
                     /GO_component="GO:0005737 - cytoplasm"
                     /GO_process="GO:0006401 - RNA catabolic process"
                     /note="RNAse HII, degrades RNA of DNA-RNA hybrids"
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease HII, degrades RNA of DNA-RNA
                     hybrids"
                     /protein_id="NP_414725.1"
                     /db_xref="GI:16128176"
                     /db_xref="ASAP:ABE-0000622"
                     /db_xref="UniProtKB/Swiss-Prot:P10442"
                     /db_xref="EcoGene:EG10861"
                     /db_xref="GeneID:944852"
                     /translation="MIEFVYPHTQLVAGVDEVGRGPLVGAVVTAAVILDPARPIAGLN
                     DSKKLSEKRRLALYEEIKEKALSWSLGRAEPHEIDELNILHATMLAMQRAVAGLHIAP
                     EYVLIDGNRCPKLPMPAMAVVKGDSRVPEISAASILAKVTRDAEMAALDIVFPQYGFA
                     QHKGYPTAFHLEKLAEHGATEHHRRSFGPVKRALGLAS"
     misc_feature    204529..205059
                     /gene="rnhB"
                     /locus_tag="b0183"
                     /gene_synonym="ECK0182; JW0178"
                     /note="Bacterial Ribonuclease HII-like; Region:
                     RNase_HII_bacteria_HII_like; cd07182"
                     /db_xref="CDD:260003"
     misc_feature    order(204538..204555,204631..204633,204736..204744,
                     204814..204822,204859..204864,204868..204870,
                     204910..204912,204973..204981,204985..204993,
                     205051..205059)
                     /gene="rnhB"
                     /locus_tag="b0183"
                     /gene_synonym="ECK0182; JW0178"
                     /note="RNA/DNA hybrid binding site [nucleotide binding];
                     other site"
                     /db_xref="CDD:260003"
     misc_feature    order(204538..204543,204814..204816,204868..204870)
                     /gene="rnhB"
                     /locus_tag="b0183"
                     /gene_synonym="ECK0182; JW0178"
                     /note="active site"
                     /db_xref="CDD:260003"
     gene            205126..208608
                     /gene="dnaE"
                     /locus_tag="b0184"
                     /gene_synonym="ECK0183; JW0179; polC; sdgC"
                     /db_xref="EcoGene:EG10238"
                     /db_xref="GeneID:944877"
     CDS             205126..208608
                     /gene="dnaE"
                     /locus_tag="b0184"
                     /gene_synonym="ECK0183; JW0179; polC; sdgC"
                     /EC_number="2.7.7.7"
                     /function="enzyme; DNA - replication, repair,
                     restriction/modification"
                     /GO_component="GO:0005737 - cytoplasm"
                     /GO_process="GO:0006261 - DNA-dependent DNA replication"
                     /note="DNA polymerase III, alpha subunit"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III alpha subunit"
                     /protein_id="NP_414726.1"
                     /db_xref="GI:16128177"
                     /db_xref="ASAP:ABE-0000624"
                     /db_xref="UniProtKB/Swiss-Prot:P10443"
                     /db_xref="EcoGene:EG10238"
                     /db_xref="GeneID:944877"
                     /translation="MSEPRFVHLRVHSDYSMIDGLAKTAPLVKKAAALGMPALAITDF
                     TNLCGLVKFYGAGHGAGIKPIVGADFNVQCDLLGDELTHLTVLAANNTGYQNLTLLIS
                     KAYQRGYGAAGPIIDRDWLIELNEGLILLSGGRMGDVGRSLLRGNSALVDECVAFYEE
                     HFPDRYFLELIRTGRPDEESYLHAAVELAEARGLPVVATNDVRFIDSSDFDAHEIRVA
                     IHDGFTLDDPKRPRNYSPQQYMRSEEEMCELFADIPEALANTVEIAKRCNVTVRLGEY
                     FLPQFPTGDMSTEDYLVKRAKEGLEERLAFLFPDEEERLKRRPEYDERLETELQVINQ
                     MGFPGYFLIVMEFIQWSKDNGVPVGPGRGSGAGSLVAYALKITDLDPLEFDLLFERFL
                     NPERVSMPDFDVDFCMEKRDQVIEHVADMYGRDAVSQIITFGTMAAKAVIRDVGRVLG
                     HPYGFVDRISKLIPPDPGMTLAKAFEAEPQLPEIYEADEEVKALIDMARKLEGVTRNA
                     GKHAGGVVIAPTKITDFAPLYCDEEGKHPVTQFDKSDVEYAGLVKFDFLGLRTLTIIN
                     WALEMINKRRAKNGEPPLDIAAIPLDDKKSFDMLQRSETTAVFQLESRGMKDLIKRLQ
                     PDCFEDMIALVALFRPGPLQSGMVDNFIDRKHGREEISYPDVQWQHESLKPVLEPTYG
                     IILYQEQVMQIAQVLSGYTLGGADMLRRAMGKKKPEEMAKQRSVFAEGAEKNGINAEL
                     AMKIFDLVEKFAGYGFNKSHSAAYALVSYQTLWLKAHYPAEFMAAVMTADMDNTEKVV
                     GLVDECWRMGLKILPPDINSGLYHFHVNDDGEIVYGIGAIKGVGEGPIEAIIEARNKG
                     GYFRELFDLCARTDTKKLNRRVLEKLIMSGAFDRLGPHRAALMNSLGDALKAADQHAK
                     AEAIGQADMFGVLAEEPEQIEQSYASCQPWPEQVVLDGERETLGLYLTGHPINQYLKE
                     IERYVGGVRLKDMHPTERGKVITAAGLVVAARVMVTKRGNRIGICTLDDRSGRLEVML
                     FTDALDKYQQLLEKDRILIVSGQVSFDDFSGGLKMTAREVMDIDEAREKYARGLAISL
                     TDRQIDDQLLNRLRQSLEPHRSGTIPVHLYYQRADARARLRFGATWRVSPSDRLLNDL
                     RGLIGSEQVELEFD"
     misc_feature    205138..208578
                     /gene="dnaE"
                     /locus_tag="b0184"
                     /gene_synonym="ECK0183; JW0179; polC; sdgC"
                     /note="DNA polymerase III subunit alpha; Validated;
                     Region: dnaE; PRK05673"
                     /db_xref="CDD:235554"
     misc_feature    205138..205968
                     /gene="dnaE"
                     /locus_tag="b0184"
                     /gene_synonym="ECK0183; JW0179; polC; sdgC"
                     /note="Polymerase and Histidinol Phosphatase domain of
                     alpha-subunit of bacterial polymerase III DnaE1; Region:
                     PHP_PolIIIA_DnaE1; cd07433"
                     /db_xref="CDD:213988"
     misc_feature    order(205153..205155,205159..205161,205180..205182,
                     205255..205257,205330..205332,205726..205728,
                     205732..205734)
                     /gene="dnaE"
                     /locus_tag="b0184"
                     /gene_synonym="ECK0183; JW0179; polC; sdgC"
                     /note="putative active site [active]"
                     /db_xref="CDD:213988"
     misc_feature    order(205297..205299,205309..205317,205927..205929)
                     /gene="dnaE"
                     /locus_tag="b0184"
                     /gene_synonym="ECK0183; JW0179; polC; sdgC"
                     /note="putative PHP Thumb interface [polypeptide binding];
                     other site"
                     /db_xref="CDD:213988"
     misc_feature    205993..207330
                     /gene="dnaE"
                     /locus_tag="b0184"
                     /gene_synonym="ECK0183; JW0179; polC; sdgC"
                     /note="Bacterial DNA polymerase III alpha subunit; Region:
                     DNA_pol3_alpha; pfam07733"
                     /db_xref="CDD:254393"
     misc_feature    207547..207819
                     /gene="dnaE"
                     /locus_tag="b0184"
                     /gene_synonym="ECK0183; JW0179; polC; sdgC"
                     /note="Helix-hairpin-helix motif; Region: HHH_6;
                     pfam14579"
                     /db_xref="CDD:258717"
     misc_feature    208108..208365
                     /gene="dnaE"
                     /locus_tag="b0184"
                     /gene_synonym="ECK0183; JW0179; polC; sdgC"
                     /note="DnaE_OBF: A subfamily of OB folds corresponding to
                     the C-terminal OB-fold nucleic acid binding domain of
                     Thermus aquaticus and Escherichia coli type C replicative
                     DNA polymerase III alpha subunit (DnaE). The DNA
                     polymerase holoenzyme of E. coli contains...; Region:
                     DnaE_OBF; cd04485"
                     /db_xref="CDD:239931"
     misc_feature    order(208108..208110,208264..208266,208270..208272,
                     208276..208278,208336..208338)
                     /gene="dnaE"
                     /locus_tag="b0184"
                     /gene_synonym="ECK0183; JW0179; polC; sdgC"
                     /note="generic binding surface II; other site"
                     /db_xref="CDD:239931"
     misc_feature    order(208123..208131,208171..208182,208186..208188,
                     208204..208212,208216..208218,208261..208263,
                     208282..208290,208315..208323)
                     /gene="dnaE"
                     /locus_tag="b0184"
                     /gene_synonym="ECK0183; JW0179; polC; sdgC"
                     /note="generic binding surface I; other site"
                     /db_xref="CDD:239931"
     gene            208621..209580
                     /gene="accA"
                     /locus_tag="b0185"
                     /gene_synonym="ECK0184; JW0180"
                     /db_xref="EcoGene:EG11647"
                     /db_xref="GeneID:944895"
     CDS             208621..209580
                     /gene="accA"
                     /locus_tag="b0185"
                     /gene_synonym="ECK0184; JW0180"
                     /EC_number="6.4.1.2"
                     /function="enzyme; Fatty acid and phosphatidic acid
                     biosynthesis"
                     /GO_component="GO:0005737 - cytoplasm"
                     /note="acetylCoA carboxylase, carboxytransferase
                     component, alpha subunit"
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase, carboxytransferase,
                     alpha subunit"
                     /protein_id="NP_414727.1"
                     /db_xref="GI:16128178"
                     /db_xref="ASAP:ABE-0000630"
                     /db_xref="UniProtKB/Swiss-Prot:P0ABD5"
                     /db_xref="EcoGene:EG11647"
                     /db_xref="GeneID:944895"
                     /translation="MSLNFLDFEQPIAELEAKIDSLTAVSRQDEKLDINIDEEVHRLR
                     EKSVELTRKIFADLGAWQIAQLARHPQRPYTLDYVRLAFDEFDELAGDRAYADDKAIV
                     GGIARLDGRPVMIIGHQKGRETKEKIRRNFGMPAPEGYRKALRLMQMAERFKMPIITF
                     IDTPGAYPGVGAEERGQSEAIARNLREMSRLGVPVVCTVIGEGGSGGALAIGVGDKVN
                     MLQYSTYSVISPEGCASILWKSADKAPLAAEAMGIIAPRLKELKLIDSIIPEPLGGAH
                     RNPEAMAASLKAQLLADLADLDVLSTEDLKNRRYQRLMSYGYA"
     misc_feature    208621..209574
                     /gene="accA"
                     /locus_tag="b0185"
                     /gene_synonym="ECK0184; JW0180"
                     /note="acetyl-CoA carboxylase carboxyltransferase subunit
                     alpha; Validated; Region: PRK05724"
                     /db_xref="CDD:235580"
     gene            209679..211820
                     /gene="ldcC"
                     /locus_tag="b0186"
                     /gene_synonym="ECK0185; JW0181; ldc; LDC2; ldcH"
                     /db_xref="EcoGene:EG13219"
                     /db_xref="GeneID:944887"
     CDS             209679..211820
                     /gene="ldcC"
                     /locus_tag="b0186"
                     /gene_synonym="ECK0185; JW0181; ldc; LDC2; ldcH"
                     /EC_number="4.1.1.18"
                     /function="enzyme; Energy metabolism, carbon: Pyruvate
                     dehydrogenase"
                     /experiment="N-terminus verified by Edman degradation:
                     PMID 9226257,9339543"
                     /GO_process="GO:0006096 - glycolysis"
                     /GO_process="GO:0016052 - carbohydrate catabolic process"
                     /codon_start=1
                     /transl_table=11
                     /product="lysine decarboxylase 2, constitutive"
                     /protein_id="NP_414728.1"
                     /db_xref="GI:16128179"
                     /db_xref="ASAP:ABE-0000633"
                     /db_xref="UniProtKB/Swiss-Prot:P52095"
                     /db_xref="EcoGene:EG13219"
                     /db_xref="GeneID:944887"
                     /translation="MNIIAIMGPHGVFYKDEPIKELESALVAQGFQIIWPQNSVDLLK
                     FIEHNPRICGVIFDWDEYSLDLCSDINQLNEYLPLYAFINTHSTMDVSVQDMRMALWF
                     FEYALGQAEDIAIRMRQYTDEYLDNITPPFTKALFTYVKERKYTFCTPGHMGGTAYQK
                     SPVGCLFYDFFGGNTLKADVSISVTELGSLLDHTGPHLEAEEYIARTFGAEQSYIVTN
                     GTSTSNKIVGMYAAPSGSTLLIDRNCHKSLAHLLMMNDVVPVWLKPTRNALGILGGIP
                     RREFTRDSIEEKVAATTQAQWPVHAVITNSTYDGLLYNTDWIKQTLDVPSIHFDSAWV
                     PYTHFHPIYQGKSGMSGERVAGKVIFETQSTHKMLAALSQASLIHIKGEYDEEAFNEA
                     FMMHTTTSPSYPIVASVETAAAMLRGNPGKRLINRSVERALHFRKEVQRLREESDGWF
                     FDIWQPPQVDEAECWPVAPGEQWHGFNDADADHMFLDPVKVTILTPGMDEQGNMSEEG
                     IPAALVAKFLDERGIVVEKTGPYNLLFLFSIGIDKTKAMGLLRGLTEFKRSYDLNLRI
                     KNMLPDLYAEDPDFYRNMRIQDLAQGIHKLIRKHDLPGLMLRAFDTLPEMIMTPHQAW
                     QRQIKGEVETIALEQLVGRVSANMILPYPPGVPLLMPGEMLTKESRTVLDFLLMLCSV
                     GQHYPGFETDIHGAKQDEDGVYRVRVLKMAG"
     misc_feature    209679..211817
                     /gene="ldcC"
                     /locus_tag="b0186"
                     /gene_synonym="ECK0185; JW0181; ldc; LDC2; ldcH"
                     /note="lysine decarboxylase LdcC; Provisional; Region:
                     PRK15399"
                     /db_xref="CDD:185297"
     misc_feature    209718..210050
                     /gene="ldcC"
                     /locus_tag="b0186"
                     /gene_synonym="ECK0185; JW0181; ldc; LDC2; ldcH"
                     /note="Orn/Lys/Arg decarboxylase, N-terminal domain;
                     Region: OKR_DC_1_N; pfam03709"
                     /db_xref="CDD:252113"
     misc_feature    210069..211001
                     /gene="ldcC"
                     /locus_tag="b0186"
                     /gene_synonym="ECK0185; JW0181; ldc; LDC2; ldcH"
                     /note="Ornithine decarboxylase family. This family belongs
                     to pyridoxal phosphate (PLP)-dependent aspartate
                     aminotransferase superfamily (fold I). The major groups in
                     this CD corresponds to ornithine decarboxylase (ODC),
                     arginine decarboxylase (ADC) and lysine...; Region:
                     Orn_deC_like; cd00615"
                     /db_xref="CDD:99739"
     misc_feature    order(210213..210215,210228..210230,210252..210254,
                     210327..210335,210339..210344,210351..210353,
                     210363..210371,210375..210380,210411..210416,
                     210774..210779,210786..210800,210849..210854,
                     210858..210866,210870..210872,210891..210893,
                     210900..210902,210909..210911,210948..210953)
                     /gene="ldcC"
                     /locus_tag="b0186"
                     /gene_synonym="ECK0185; JW0181; ldc; LDC2; ldcH"
                     /note="homodimer interface [polypeptide binding]; other
                     site"
                     /db_xref="CDD:99739"
     misc_feature    order(210333..210341,210411..210413,210417..210419,
                     210588..210590,210666..210668,210672..210677,
                     210768..210770,210774..210779)
                     /gene="ldcC"
                     /locus_tag="b0186"
                     /gene_synonym="ECK0185; JW0181; ldc; LDC2; ldcH"
                     /note="pyridoxal 5'-phosphate binding site [chemical
                     binding]; other site"
                     /db_xref="CDD:99739"
     misc_feature    210777..210779
                     /gene="ldcC"
                     /locus_tag="b0186"
                     /gene_synonym="ECK0185; JW0181; ldc; LDC2; ldcH"
                     /note="catalytic residue [active]"
                     /db_xref="CDD:99739"
     misc_feature    211386..211790
                     /gene="ldcC"
                     /locus_tag="b0186"
                     /gene_synonym="ECK0185; JW0181; ldc; LDC2; ldcH"
                     /note="Orn/Lys/Arg decarboxylase, C-terminal domain;
                     Region: OKR_DC_1_C; pfam03711"
                     /db_xref="CDD:112521"
     gene            211877..212266
                     /gene="yaeR"
                     /locus_tag="b0187"
                     /gene_synonym="ECK0186; JW0182"
                     /db_xref="EcoGene:EG13224"
                     /db_xref="GeneID:944875"
     CDS             211877..212266
                     /gene="yaeR"
                     /locus_tag="b0187"
                     /gene_synonym="ECK0186; JW0182"
                     /codon_start=1
                     /transl_table=11
                     /product="putative lyase"
                     /protein_id="NP_414729.4"
                     /db_xref="GI:90111096"
                     /db_xref="ASAP:ABE-0000635"
                     /db_xref="UniProtKB/Swiss-Prot:P52096"
                     /db_xref="EcoGene:EG13224"
                     /db_xref="GeneID:944875"
                     /translation="MLGLKQVHHIAIIATDYAVSKAFYCDILGFTLQSEVYREARDSW
                     KGDLALNGQYVIELFSFPFPPERPSRPEACGLRHLAFSVDDIDAAVAHLESHNVKCET
                     IRVDPYTQKRFTFFNDPDGLPLELYEQ"
     misc_feature    211886..212260
                     /gene="yaeR"
                     /locus_tag="b0187"
                     /gene_synonym="ECK0186; JW0182"
                     /note="This conserved domain belongs to a superfamily
                     including the bleomycin resistance protein, glyoxalase I,
                     and type I ring-cleaving dioxygenases; Region:
                     Glo_EDI_BRP_like_1; cd08352"
                     /db_xref="CDD:211358"
     misc_feature    order(211901..211903,212108..212110,212249..212251)
                     /gene="yaeR"
                     /locus_tag="b0187"
                     /gene_synonym="ECK0186; JW0182"
                     /note="putative metal binding site [ion binding]; other
                     site"
                     /db_xref="CDD:211358"
     gene            212331..213629
                     /gene="tilS"
                     /locus_tag="b0188"
                     /gene_synonym="ECK0187; JW0183; mesJ; yaeN"
                     /db_xref="EcoGene:EG13220"
                     /db_xref="GeneID:944889"
     CDS             212331..213629
                     /gene="tilS"
                     /locus_tag="b0188"
                     /gene_synonym="ECK0187; JW0183; mesJ; yaeN"
                     /EC_number="6.1.1.5"
                     /function="enzyme; tRNA modification"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA(Ile)-lysidine synthetase"
                     /protein_id="NP_414730.1"
                     /db_xref="GI:16128181"
                     /db_xref="ASAP:ABE-0000638"
                     /db_xref="UniProtKB/Swiss-Prot:P52097"
                     /db_xref="EcoGene:EG13220"
                     /db_xref="GeneID:944889"
                     /translation="MTLTLNRQLLTSRQILVAFSGGLDSTVLLHQLVQWRTENPGVAL
                     RAIHVHHGLSANADAWVTHCENVCQQWQVPLVVERVQLAQEGLGIEAQARQARYQAFA
                     RTLLPGEVLVTAQHLDDQCETFLLALKRGSGPAGLSAMAEVSEFAGTRLIRPLLARTR
                     GELVQWARQYDLRWIEDESNQDDSYDRNFLRLRVVPLLQQRWPHFAEATARSAALCAE
                     QESLLDELLADDLAHCQSPQGTLQIVPMLAMSDARRAAIIRRWLAGQNAPMPSRDALV
                     RIWQEVALAREDASPCLRLGAFEIRRYQSQLWWIKSVTGQSENIVPWQTWLQPLELPA
                     GLGSVQLNAGGDIRPPRADEAVSVRFKAPGLLHIVGRNGGRKLKKIWQELGVPPWLRD
                     TTPLLFYGETLIAAAGVFVTQEGVAEGENGVSFVWQKTLS"
     misc_feature    212331..213626
                     /gene="tilS"
                     /locus_tag="b0188"
                     /gene_synonym="ECK0187; JW0183; mesJ; yaeN"
                     /note="tRNA(Ile)-lysidine synthetase; Provisional; Region:
                     tilS; PRK10660"
                     /db_xref="CDD:182626"
     misc_feature    212370..212918
                     /gene="tilS"
                     /locus_tag="b0188"
                     /gene_synonym="ECK0187; JW0183; mesJ; yaeN"
                     /note="N-terminal domain of predicted ATPase of the
                     PP-loop faimly implicated in cell cycle control [Cell
                     division and chromosome partitioning]. This is a subfamily
                     of Adenine nucleotide alpha hydrolases
                     superfamily.Adeninosine nucleotide alpha hydrolases...;
                     Region: PP-ATPase; cd01992"
                     /db_xref="CDD:238950"
     misc_feature    order(212382..212390,212394..212405,212472..212474,
                     212478..212480)
                     /gene="tilS"
                     /locus_tag="b0188"
                     /gene_synonym="ECK0187; JW0183; mesJ; yaeN"
                     /note="Ligand Binding Site [chemical binding]; other site"
                     /db_xref="CDD:238950"
     misc_feature    213051..213257
                     /gene="tilS"
                     /locus_tag="b0188"
                     /gene_synonym="ECK0187; JW0183; mesJ; yaeN"
                     /note="TilS substrate binding domain; Region: TilS;
                     pfam09179"
                     /db_xref="CDD:255218"
     misc_feature    213396..213599
                     /gene="tilS"
                     /locus_tag="b0188"
                     /gene_synonym="ECK0187; JW0183; mesJ; yaeN"
                     /note="TilS substrate C-terminal domain; Region: TilS_C;
                     pfam11734"
                     /db_xref="CDD:256581"
     repeat_region   213632..213668
                     /note="REP15 (repetitive extragenic palindromic) element;
                     contains 1 REP sequences"
     gene            complement(213678..213932)
                     /gene="rof"
                     /locus_tag="b0189"
                     /gene_synonym="ECK0188; JW0184; mesJ; yaeO"
                     /db_xref="EcoGene:EG13221"
                     /db_xref="GeneID:944891"
     CDS             complement(213678..213932)
                     /gene="rof"
                     /locus_tag="b0189"
                     /gene_synonym="ECK0188; JW0184; mesJ; yaeO"
                     /experiment="N-terminus verified by Edman degradation:
                     PMID 10739205"
                     /GO_component="GO:0005737 - cytoplasm"
                     /GO_process="GO:0006350 - transcription"
                     /codon_start=1
                     /transl_table=11
                     /product="modulator of Rho-dependent transcription
                     termination"
                     /protein_id="NP_414731.2"
                     /db_xref="GI:90111097"
                     /db_xref="ASAP:ABE-0000641"
                     /db_xref="UniProtKB/Swiss-Prot:P0AFW8"
                     /db_xref="EcoGene:EG13221"
                     /db_xref="GeneID:944891"
                     /translation="MNDTYQPINCDDYDNLELACQHHLMLTLELKDGEKLQAKASDLV
                     SRKNVEYLVVEAAGETRELRLDKITSFSHPEIGTVVVSES"
     misc_feature    complement(213681..213932)
                     /gene="rof"
                     /locus_tag="b0189"
                     /gene_synonym="ECK0188; JW0184; mesJ; yaeO"
                     /note="Rho-binding antiterminator; Provisional; Region:
                     PRK11625"
                     /db_xref="CDD:183241"
     gene            complement(213925..214125)
                     /gene="yaeP"
                     /locus_tag="b4406"
                     /gene_synonym="ECK0189; JW0185"
                     /db_xref="EcoGene:EG13222"
                     /db_xref="GeneID:1450233"
     CDS             complement(213925..214125)
                     /gene="yaeP"
                     /locus_tag="b4406"
                     /gene_synonym="ECK0189; JW0185"
                     /note="conserved hypothetical protein"
                     /codon_start=1
                     /transl_table=11
                     /product="UPF0253 family protein"
                     /protein_id="YP_026160.1"
                     /db_xref="GI:49176004"
                     /db_xref="ASAP:ABE-0047214"
                     /db_xref="UniProtKB/Swiss-Prot:P0A8K5"
                     /db_xref="EcoGene:EG13222"
                     /db_xref="GeneID:1450233"
                     /translation="MEKYCELIRKRYAEIASGDLGYVPDALGCVLKVLNEMAADDALS
                     EAVREKAAYAAANLLVSDYVNE"
     misc_feature    complement(213928..214125)
                     /gene="yaeP"
                     /locus_tag="b4406"
                     /gene_synonym="ECK0189; JW0185"
                     /note="hypothetical protein; Provisional; Region:
                     PRK04964"
                     /db_xref="CDD:179901"
     gene            214291..214836
                     /gene="yaeQ"
                     /locus_tag="b0190"
                     /gene_synonym="ECK0190; JW0186"
                     /db_xref="EcoGene:EG13223"
                     /db_xref="GeneID:946809"
     CDS             214291..214836
                     /gene="yaeQ"
                     /locus_tag="b0190"
                     /gene_synonym="ECK0190; JW0186"
                     /function="putative enzyme; Not classified"
                     /codon_start=1
                     /transl_table=11
                     /product="PDDEXK superfamily protein"
                     /protein_id="NP_414732.1"
                     /db_xref="GI:16128183"
                     /db_xref="ASAP:ABE-0000648"
                     /db_xref="UniProtKB/Swiss-Prot:P0AA97"
                     /db_xref="EcoGene:EG13223"
                     /db_xref="GeneID:946809"
                     /translation="MALKATIYKATVNVADLDRNQFLDASLTLARHPSETQERMMLRL
                     LAWLKYADERLQFTRGLCADDEPEAWLRNDHLGIDLWIELGLPDERRIKKACTQAAEV
                     ALFTYNSRAAQIWWQQNQSKCVQFANLSVWYLDDEQLAKVSAFADRTMTLQATIQDGV
                     IWLSDDKNNLEVNLTAWQQPS"
     misc_feature    214291..214833
                     /gene="yaeQ"
                     /locus_tag="b0190"
                     /gene_synonym="ECK0190; JW0186"
                     /note="Uncharacterized protein conserved in bacteria
                     [Function unknown]; Region: COG4681"
                     /db_xref="CDD:227026"
     gene            214833..215255
                     /gene="arfB"
                     /locus_tag="b0191"
                     /gene_synonym="ECK0191; JW0187; yaeJ"
                     /db_xref="EcoGene:EG12354"
                     /db_xref="GeneID:946046"
     CDS             214833..215255
                     /gene="arfB"
                     /locus_tag="b0191"
                     /gene_synonym="ECK0191; JW0187; yaeJ"
                     /codon_start=1
                     /transl_table=11
                     /product="alternative stalled-ribosome rescue factor B;
                     peptidyl-tRNA hydrolase, ribosome-attached"
                     /protein_id="NP_414733.1"
                     /db_xref="GI:16128184"
                     /db_xref="ASAP:ABE-0000650"
                     /db_xref="UniProtKB/Swiss-Prot:P40711"
                     /db_xref="EcoGene:EG12354"
                     /db_xref="GeneID:946046"
                     /translation="MIVISRHVAIPDGELEITAIRAQGAGGQHVNKTSTAIHLRFDIR
                     ASSLPEYYKERLLAASHHLISSDGVIVIKAQEYRSQELNREAALARLVAMIKELTTEK
                     KARRPTRPTRASKERRLASKAQKSSVKAMRGKVRSGRE"
     misc_feature    214833..215240
                     /gene="arfB"
                     /locus_tag="b0191"
                     /gene_synonym="ECK0191; JW0187; yaeJ"
                     /note="hypothetical protein; Provisional; Region:
                     PRK09256"
                     /db_xref="CDD:181730"
     misc_feature    <214836..215252
                     /gene="arfB"
                     /locus_tag="b0191"
                     /gene_synonym="ECK0191; JW0187; yaeJ"
                     /note="Protein chain release factor B [Translation,
                     ribosomal structure and biogenesis]; Region: PrfB;
                     COG1186"
                     /db_xref="CDD:224107"
     gene            215269..215979
                     /gene="nlpE"
                     /locus_tag="b0192"
                     /gene_synonym="cutF; ECK0192; JW0188"
                     /db_xref="EcoGene:EG12137"
                     /db_xref="GeneID:946782"
     CDS             215269..215979
                     /gene="nlpE"
                     /locus_tag="b0192"
                     /gene_synonym="cutF; ECK0192; JW0188"
                     /function="putative transport; Detoxification"
                     /GO_component="GO:0009274 - peptidoglycan-based cell wall"
                     /GO_component="GO:0009279 - cell outer membrane"
                     /GO_process="GO:0006805 - xenobiotic metabolic process"
                     /note="copper homeostasis protein (lipoprotein)"
                     /codon_start=1
                     /transl_table=11
                     /product="lipoprotein involved with copper homeostasis and
                     adhesion"
                     /protein_id="NP_414734.1"
                     /db_xref="GI:16128185"
                     /db_xref="ASAP:ABE-0000652"
                     /db_xref="UniProtKB/Swiss-Prot:P40710"
                     /db_xref="EcoGene:EG12137"
                     /db_xref="GeneID:946782"
                     /translation="MVKKAIVTAMAVISLFTLMGCNNRAEVDTLSPAQAAELKPMPQS
                     WRGVLPCADCEGIETSLFLEKDGTWVMNERYLGAREEPSSFASYGTWARTADKLVLTD
                     SKGEKSYYRAKGDALEMLDREGNPIESQFNYTLEAAQSSLPMTPMTLRGMYFYMADAA
                     TFTDCATGKRFMVANNAELERSYLAARGHSEKPVLLSVEGHFTLEGNPDTGAPTKVLA
                     PDTAGKFYPNQDCSSLGQ"
     misc_feature    215269..215967
                     /gene="nlpE"
                     /locus_tag="b0192"
                     /gene_synonym="cutF; ECK0192; JW0188"
                     /note="lipoprotein involved with copper homeostasis and
                     adhesion; Provisional; Region: PRK10523"
                     /db_xref="CDD:236708"
     misc_feature    215269..215952
                     /gene="nlpE"
                     /locus_tag="b0192"
                     /gene_synonym="cutF; ECK0192; JW0188"
                     /note="Uncharacterized lipoprotein NlpE involved in copper
                     resistance [Cell envelope biogenesis, outer membrane /
                     Inorganic ion transport and metabolism]; Region: CutF;
                     COG3015"
                     /db_xref="CDD:225560"
     repeat_region   216027..216137
                     /note="RIP16 (repetitive extragenic palindromic) element;
                     contains 2 REP sequences and 1 IHF site"
     gene            complement(216179..217003)
                     /gene="yaeF"
                     /locus_tag="b0193"
                     /gene_synonym="ECK0193; JW5016; yaeK"
                     /db_xref="EcoGene:EG12138"
                     /db_xref="GeneID:944892"
     CDS             complement(216179..217003)
                     /gene="yaeF"
                     /locus_tag="b0193"
                     /gene_synonym="ECK0193; JW5016; yaeK"
                     /codon_start=1
                     /transl_table=11
                     /product="putative lipoprotein"
                     /protein_id="NP_414735.4"
                     /db_xref="GI:90111098"
                     /db_xref="ASAP:ABE-0000655"
                     /db_xref="UniProtKB/Swiss-Prot:P37056"
                     /db_xref="EcoGene:EG12138"
                     /db_xref="GeneID:944892"
                     /translation="MDKPKAYCRLFLPSFLLLSACTVDISQPDPSATAVDAEAKTWAV
                     KFQHQSSFTEQSIKEITAPDLKPGDLLFSSSLGVTSFGIRVFSTSSVSHVAIFLGDNN
                     VAEATGAGVQIVSLKKAMKHSDKLFVLRVPDLTPQQATDITAFANKIKDSGYNYRGIV
                     EFIPFMVTRQMCSLNPFSEDFRQQCVSGLAKAQLSSVGEGDKKSWFCSEFVTDAFAKA
                     GHPLTLAQSGWISPADLMHMRIGDVSAFKPETQLQYVGHLKPGIYIKAGRFVGLTR"
     misc_feature    complement(216182..217003)
                     /gene="yaeF"
                     /locus_tag="b0193"
                     /gene_synonym="ECK0193; JW5016; yaeK"
                     /note="hypothetical protein; Provisional; Region:
                     PRK11479"
                     /db_xref="CDD:183157"
     misc_feature    complement(216656..>216832)
                     /gene="yaeF"
                     /locus_tag="b0193"
                     /gene_synonym="ECK0193; JW5016; yaeK"
                     /note="Cell wall-associated hydrolases
                     (invasion-associated proteins) [Cell envelope biogenesis,
                     outer membrane]; Region: Spr; COG0791"
                     /db_xref="CDD:223862"
     gene            complement(217057..218775)
                     /gene="proS"
                     /locus_tag="b0194"
                     /gene_synonym="drpA; ECK0194; JW0190"
                     /db_xref="EcoGene:EG10770"
                     /db_xref="GeneID:949116"
     CDS             complement(217057..218775)
                     /gene="proS"
                     /locus_tag="b0194"
                     /gene_synonym="drpA; ECK0194; JW0190"
                     /EC_number="6.1.1.15"
                     /function="enzyme; Aminoacyl tRNA synthetases, tRNA
                     modification"
                     /experiment="N-terminus verified by Edman degradation:
                     PMID 2203971,9298646"
                     /GO_component="GO:0005737 - cytoplasm"
                     /GO_process="GO:0006418 - tRNA aminoacylation for protein
                     translation"
                     /note="proline tRNA synthetase"
                     /codon_start=1
                     /transl_table=11
                     /product="prolyl-tRNA synthetase"
                     /protein_id="NP_414736.1"
                     /db_xref="GI:16128187"
                     /db_xref="ASAP:ABE-0000657"
                     /db_xref="UniProtKB/Swiss-Prot:P16659"
                     /db_xref="EcoGene:EG10770"
                     /db_xref="GeneID:949116"
                     /translation="MRTSQYLLSTLKETPADAEVISHQLMLRAGMIRKLASGLYTWLP
                     TGVRVLKKVENIVREEMNNAGAIEVSMPVVQPADLWQESGRWEQYGPELLRFVDRGER
                     PFVLGPTHEEVITDLIRNELSSYKQLPLNFYQIQTKFRDEVRPRFGVMRSREFLMKDA
                     YSFHTSQESLQETYDAMYAAYSKIFSRMGLDFRAVQADTGSIGGSASHEFQVLAQSGE
                     DDVVFSDTSDYAANIELAEAIAPKEPRAAATQEMTLVDTPNAKTIAELVEQFNLPIEK
                     TVKTLLVKAVEGSSFPQVALLVRGDHELNEVKAEKLPQVASPLTFATEEEIRAVVKAG
                     PGSLGPVNMPIPVVIDRTVAAMSDFAAGANIDGKHYFGINWDRDVATPEVADIRNVVA
                     GDPSPDGQGRLLIKRGIEVGHIFQLGTKYSEALKASVQGEDGRNQILTMGCYGIGVTR
                     VVAAAIEQNYDERGIVWPDAIAPFQVAILPMNMHKSFRVQELAEKLYSELRAQGIEVL
                     LDDRKERPGVMFADMELIGIPHTIVLGDRNLDNDDIEYKYRRNGEKQLIKTGDIVEYL
                     VKQIKG"
     misc_feature    complement(217063..218775)
                     /gene="proS"
                     /locus_tag="b0194"
                     /gene_synonym="drpA; ECK0194; JW0190"
                     /note="prolyl-tRNA synthetase; Provisional; Region:
                     PRK09194"
                     /db_xref="CDD:236405"
     misc_feature    complement(217402..218727)
                     /gene="proS"
                     /locus_tag="b0194"
                     /gene_synonym="drpA; ECK0194; JW0190"
                     /note="Prolyl-tRNA synthetase (ProRS) class II core
                     catalytic domain. ProRS is a homodimer. It is responsible
                     for the attachment of proline to the 3' OH group of ribose
                     of the appropriate tRNA. This domain is primarily
                     responsible for ATP-dependent...; Region: ProRS_core_prok;
                     cd00779"
                     /db_xref="CDD:238402"
     misc_feature    complement(order(218314..218316,218365..218367,
                     218425..218427,218479..218493,218497..218499,
                     218557..218562,218566..218574,218623..218625,
                     218644..218655,218674..218679))
                     /gene="proS"
                     /locus_tag="b0194"
                     /gene_synonym="drpA; ECK0194; JW0190"
                     /note="dimer interface [polypeptide binding]; other site"
                     /db_xref="CDD:238402"
     misc_feature    complement(218557..218580)
                     /gene="proS"
                     /locus_tag="b0194"
                     /gene_synonym="drpA; ECK0194; JW0190"
                     /note="motif 1; other site"
                     /db_xref="CDD:238402"
     misc_feature    complement(order(217426..217428,217435..217437,
                     217441..217449,217537..217539,217543..217548,
                     217552..217554,218299..218301,218305..218307,
                     218311..218313,218320..218328,218350..218352,
                     218356..218358,218443..218445,218449..218451))
                     /gene="proS"
                     /locus_tag="b0194"
                     /gene_synonym="drpA; ECK0194; JW0190"
                     /note="active site"
                     /db_xref="CDD:238402"
     misc_feature    complement(218350..218361)
                     /gene="proS"
                     /locus_tag="b0194"
                     /gene_synonym="drpA; ECK0194; JW0190"
                     /note="motif 2; other site"
                     /db_xref="CDD:238402"
     misc_feature    complement(217615..218100)
                     /gene="proS"
                     /locus_tag="b0194"
                     /gene_synonym="drpA; ECK0194; JW0190"
                     /note="INS is an amino acid-editing domain inserted (INS)
                     into the bacterial class II prolyl-tRNA synthetase (ProRS)
                     however, this CD is not exclusively bacterial. It is also
                     found at the N-terminus of the eukaryotic/archaea-like
                     ProRS's of yeasts and...; Region: ProRS-INS; cd04334"
                     /db_xref="CDD:239826"
     misc_feature    complement(order(217690..217692,217765..217770,
                     217939..217941))
                     /gene="proS"
                     /locus_tag="b0194"
                     /gene_synonym="drpA; ECK0194; JW0190"
                     /note="putative deacylase active site [active]"
                     /db_xref="CDD:239826"
     misc_feature    complement(217426..217443)
                     /gene="proS"
                     /locus_tag="b0194"
                     /gene_synonym="drpA; ECK0194; JW0190"
                     /note="motif 3; other site"
                     /db_xref="CDD:238402"
     misc_feature    complement(217075..217359)
                     /gene="proS"
                     /locus_tag="b0194"
                     /gene_synonym="drpA; ECK0194; JW0190"
                     /note="ProRS Prolyl-anticodon binding domain, short
                     version found predominantly in bacteria. ProRS belongs to
                     class II aminoacyl-tRNA synthetases (aaRS). This alignment
                     contains the anticodon binding domain, which is
                     responsible for specificity in tRNA-binding; Region:
                     ProRS_anticodon_short; cd00861"
                     /db_xref="CDD:238438"
     misc_feature    complement(order(217135..217137,217141..217143,
                     217171..217173,217195..217197,217213..217215,
                     217330..217335))
                     /gene="proS"
                     /locus_tag="b0194"
                     /gene_synonym="drpA; ECK0194; JW0190"
                     /note="anticodon binding site; other site"
                     /db_xref="CDD:238438"
     gene            complement(218887..219594)
                     /gene="tsaA"
                     /locus_tag="b0195"
                     /gene_synonym="ECK0195; JW0191; yaeB"
                     /db_xref="EcoGene:EG11503"
                     /db_xref="GeneID:949112"
     CDS             complement(218887..219594)
                     /gene="tsaA"
                     /locus_tag="b0195"
                     /gene_synonym="ECK0195; JW0191; yaeB"
                     /function="enzyme; tRNA modification"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA-Thr(GGU) m(6)t(6)A37 methyltransferase,
                     SAM-dependent"
                     /protein_id="NP_414737.1"
                     /db_xref="GI:16128188"
                     /db_xref="ASAP:ABE-0000661"
                     /db_xref="UniProtKB/Swiss-Prot:P28634"
                     /db_xref="EcoGene:EG11503"
                     /db_xref="GeneID:949112"
                     /translation="MSSFQFEQIGVIRSPYKEKFAVPRQPGLVKSANGELHLIAPYNQ
                     ADAVRGLEAFSHLWILFVFHQTMEGGWRPTVRPPRLGGNARMGVFATRSTFRPNPIGM
                     SLVELKEVVCHKDSVILKLGSLDLVDGTPVVDIKPYLPFAESLPDASASYAQSAPAAE
                     MAVSFTAEVEKQLLTLEKRYPQLTLFIREVLAQDPRPAYRKGEETGKTYAVWLHDFNV
                     RWRVTDAGFEVFALEPR"
     misc_feature    complement(219181..219570)
                     /gene="tsaA"
                     /locus_tag="b0195"
                     /gene_synonym="ECK0195; JW0191; yaeB"
                     /note="Escherichia coli YaeB and related proteins; Region:
                     UPF0066; cd09281"
                     /db_xref="CDD:187753"
     misc_feature    complement(order(219181..219198,219295..219297,
                     219301..219303,219307..219309,219319..219336,
                     219409..219411,219421..219423,219442..219444,
                     219448..219456,219568..219570))
                     /gene="tsaA"
                     /locus_tag="b0195"
                     /gene_synonym="ECK0195; JW0191; yaeB"
                     /note="homodimer interaction site [polypeptide binding];
                     other site"
                     /db_xref="CDD:187753"
     misc_feature    complement(order(219205..219207,219220..219222,
                     219289..219291,219295..219297,219319..219321,
                     219403..219408,219412..219414))
                     /gene="tsaA"
                     /locus_tag="b0195"
                     /gene_synonym="ECK0195; JW0191; yaeB"
                     /note="cofactor binding site; other site"
                     /db_xref="CDD:187753"
     gene            complement(219591..219995)
                     /gene="rcsF"
                     /locus_tag="b0196"
                     /gene_synonym="ECK0196; JW0192"
                     /db_xref="EcoGene:EG11502"
                     /db_xref="GeneID:949113"
     CDS             complement(219591..219995)
                     /gene="rcsF"
                     /locus_tag="b0196"
                     /gene_synonym="ECK0196; JW0192"
                     /function="regulator; Surface polysaccharides & antigens"
                     /GO_function="GO:0042280 - cell surface antigen activity,
                     host-interacting"
                     /GO_process="GO:0009242 - colanic acid biosynthetic
                     process"
                     /note="regulator in colanic acid synthesis; interacts with
                     RcsB"
                     /codon_start=1
                     /transl_table=11
                     /product="putative outer membrane protein"
                     /protein_id="NP_414738.1"
                     /db_xref="GI:16128189"
                     /db_xref="ASAP:ABE-0000663"
                     /db_xref="UniProtKB/Swiss-Prot:P69411"
                     /db_xref="EcoGene:EG11502"
                     /db_xref="GeneID:949113"
                     /translation="MRALPICLVALMLSGCSMLSRSPVEPVQSTAPQPKAEPAKPKAP
                     RATPVRIYTNAEELVGKPFRDLGEVSGDSCQASNQDSPPSIPTARKRMQINASKMKAN
                     AVLLHSCEVTSGTPGCYRQAVCIGSALNITAK"
     misc_feature    complement(219597..219995)
                     /gene="rcsF"
                     /locus_tag="b0196"
                     /gene_synonym="ECK0196; JW0192"
                     /note="outer membrane lipoprotein; Reviewed; Region: rcsF;
                     PRK10781"
                     /db_xref="CDD:182725"
     gene            complement(220113..220928)
                     /gene="metQ"
                     /locus_tag="b0197"
                     /gene_synonym="ECK0197; JW0193; metD; yaeC"
                     /db_xref="EcoGene:EG11504"
                     /db_xref="GeneID:944893"
     CDS             complement(220113..220928)
                     /gene="metQ"
                     /locus_tag="b0197"
                     /gene_synonym="ECK0197; JW0193; metD; yaeC"
                     /function="transport; Transport of small molecules: Amino
                     acids, amines"
                     /GO_component="GO:0009274 - peptidoglycan-based cell wall"
                     /GO_component="GO:0042597 - periplasmic space"
                     /note="D-methionine transport protein (ABC superfamily,
                     peri_bind)"
                     /codon_start=1
                     /transl_table=11
                     /product="DL-methionine transporter subunit"
                     /protein_id="NP_414739.1"
                     /db_xref="GI:16128190"
                     /db_xref="ASAP:ABE-0000666"
                     /db_xref="UniProtKB/Swiss-Prot:P28635"
                     /db_xref="EcoGene:EG11504"
                     /db_xref="GeneID:944893"
                     /translation="MAFKFKTFAAVGALIGSLALVGCGQDEKDPNHIKVGVIVGAEQQ
                     VAEVAQKVAKDKYGLDVELVTFNDYVLPNEALSKGDIDANAFQHKPYLDQQLKDRGYK
                     LVAVGNTFVYPIAGYSKKIKSLDELQDGSQVAVPNDPTNLGRSLLLLQKVGLIKLKDG
                     VGLLPTVLDVVENPKNLKIVELEAPQLPRSLDDAQIALAVINTTYASQIGLTPAKDGI
                     FVEDKESPYVNLIVTREDNKDAENVKKFVQAYQSDEVYEAANKVFNGGAVKGW"
     misc_feature    complement(220116..220928)
                     /gene="metQ"
                     /locus_tag="b0197"
                     /gene_synonym="ECK0197; JW0193; metD; yaeC"
                     /note="DL-methionine transporter substrate-binding
                     subunit; Provisional; Region: metQ; PRK11063"
                     /db_xref="CDD:182939"
     gene            complement(220968..221621)
                     /gene="metI"
                     /locus_tag="b0198"
                     /gene_synonym="ECK0198; JW0194; metD; yaeE"
                     /db_xref="EcoGene:EG11737"
                     /db_xref="GeneID:944894"
     CDS             complement(220968..221621)
                     /gene="metI"
                     /locus_tag="b0198"
                     /gene_synonym="ECK0198; JW0194; metD; yaeE"
                     /function="transport; Transport of small molecules: Amino
                     acids, amines"
                     /GO_component="GO:0009274 - peptidoglycan-based cell wall"
                     /GO_component="GO:0019866 - organelle inner membrane"
                     /note="D- and L-methionine transport protein (ABC
                     superfamily, membrane)"
                     /codon_start=1
                     /transl_table=11
                     /product="DL-methionine transporter subunit"
                     /protein_id="NP_414740.1"
                     /db_xref="GI:16128191"
                     /db_xref="ASAP:ABE-0000668"
                     /db_xref="UniProtKB/Swiss-Prot:P31547"
                     /db_xref="EcoGene:EG11737"
                     /db_xref="GeneID:944894"
                     /translation="MSEPMMWLLVRGVWETLAMTFVSGFFGFVIGLPVGVLLYVTRPG
                     QIIANAKLYRTVSAIVNIFRSIPFIILLVWMIPFTRVIVGTSIGLQAAIVPLTVGAAP
                     FIARMVENALLEIPTGLIEASRAMGATPMQIVRKVLLPEALPGLVNAATITLITLVGY
                     SAMGGAVGAGGLGQIGYQYGYIGYNATVMNTVLVLLVILVYLIQFAGDRIVRAVTRK"
     misc_feature    complement(221091..221582)
                     /gene="metI"
                     /locus_tag="b0198"
                     /gene_synonym="ECK0198; JW0194; metD; yaeE"
                     /note="Transmembrane subunit (TM) found in Periplasmic
                     Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC)
                     transporters which generally bind type 2 PBPs. These types
                     of transporters consist of a PBP, two TMs, and two
                     cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2;
                     cd06261"
                     /db_xref="CDD:119394"
     misc_feature    complement(order(221124..221129,221136..221147,
                     221166..221168,221175..221180,221220..221222,
                     221271..221273,221280..221285,221295..221297,
                     221301..221306,221313..221315,221319..221321,
                     221325..221330,221394..221396,221400..221405,
                     221412..221441,221445..221456,221505..221507,
                     221520..221525,221532..221537))
                     /gene="metI"
                     /locus_tag="b0198"
                     /gene_synonym="ECK0198; JW0194; metD; yaeE"
                     /note="dimer interface [polypeptide binding]; other site"
                     /db_xref="CDD:119394"
     misc_feature    complement(order(221130..221147,221394..221438))
                     /gene="metI"
                     /locus_tag="b0198"
                     /gene_synonym="ECK0198; JW0194; metD; yaeE"
                     /note="conserved gate region; other site"
                     /db_xref="CDD:119394"
     misc_feature    complement(order(221091..221093,221127..221129,
                     221343..221345,221394..221396))
                     /gene="metI"
                     /locus_tag="b0198"
                     /gene_synonym="ECK0198; JW0194; metD; yaeE"
                     /note="putative PBP binding loops; other site"
                     /db_xref="CDD:119394"
     misc_feature    complement(order(221199..221201,221211..221216,
                     221232..221270))
                     /gene="metI"
                     /locus_tag="b0198"
                     /gene_synonym="ECK0198; JW0194; metD; yaeE"
                     /note="ABC-ATPase subunit interface; other site"
                     /db_xref="CDD:119394"
     gene            complement(221614..222645)
                     /gene="metN"
                     /locus_tag="b0199"
                     /gene_synonym="abc; ECK0199; JW0195; metD"
                     /db_xref="EcoGene:EG11621"
                     /db_xref="GeneID:944896"
     CDS             complement(221614..222645)
                     /gene="metN"
                     /locus_tag="b0199"
                     /gene_synonym="abc; ECK0199; JW0195; metD"
                     /function="transport; Transport of small molecules: Amino
                     acids, amines"
                     /GO_component="GO:0005737 - cytoplasm"
                     /note="D- and L-methionine transport protein (ABC
                     superfamily, atp_bind)"
                     /codon_start=1
                     /transl_table=11
                     /product="DL-methionine transporter subunit"
                     /protein_id="NP_414741.1"
                     /db_xref="GI:16128192"
                     /db_xref="ASAP:ABE-0000671"
                     /db_xref="UniProtKB/Swiss-Prot:P30750"
                     /db_xref="EcoGene:EG11621"
                     /db_xref="GeneID:944896"
                     /translation="MIKLSNITKVFHQGTRTIQALNNVSLHVPAGQIYGVIGASGAGK
                     STLIRCVNLLERPTEGSVLVDGQELTTLSESELTKARRQIGMIFQHFNLLSSRTVFGN
                     VALPLELDNTPKDEVKRRVTELLSLVGLGDKHDSYPSNLSGGQKQRVAIARALASNPK
                     VLLCDEATSALDPATTRSILELLKDINRRLGLTILLITHEMDVVKRICDCVAVISNGE
                     LIEQDTVSEVFSHPKTPLAQKFIQSTLHLDIPEDYQERLQAEPFTDCVPMLRLEFTGQ
                     SVDAPLLSETARRFNVNNNIISAQMDYAGGVKFGIMLTEMHGTQQDTQAAIAWLQEHH
                     VKVEVLGYV"
     misc_feature    complement(221617..222645)
                     /gene="metN"
                     /locus_tag="b0199"
                     /gene_synonym="abc; ECK0199; JW0195; metD"
                     /note="DL-methionine transporter ATP-binding subunit;
                     Provisional; Region: metN; PRK11153"
                     /db_xref="CDD:236863"
     misc_feature    complement(221947..222645)
                     /gene="metN"
                     /locus_tag="b0199"
                     /gene_synonym="abc; ECK0199; JW0195; metD"
                     /note="ATP-binding cassette domain of methionine
                     transporter; Region: ABC_MetN_methionine_transporter;
                     cd03258"
                     /db_xref="CDD:213225"
     misc_feature    complement(222511..222534)
                     /gene="metN"
                     /locus_tag="b0199"
                     /gene_synonym="abc; ECK0199; JW0195; metD"
                     /note="Walker A/P-loop; other site"
                     /db_xref="CDD:213225"
     misc_feature    complement(order(222049..222051,222148..222153,
                     222379..222381,222508..222516,222520..222525))
                     /gene="metN"
                     /locus_tag="b0199"
                     /gene_synonym="abc; ECK0199; JW0195; metD"
                     /note="ATP binding site [chemical binding]; other site"
                     /db_xref="CDD:213225"
     misc_feature    complement(222379..222390)
                     /gene="metN"
                     /locus_tag="b0199"
                     /gene_synonym="abc; ECK0199; JW0195; metD"
                     /note="Q-loop/lid; other site"
                     /db_xref="CDD:213225"
     misc_feature    complement(222196..222225)
                     /gene="metN"
                     /locus_tag="b0199"
                     /gene_synonym="abc; ECK0199; JW0195; metD"
                     /note="ABC transporter signature motif; other site"
                     /db_xref="CDD:213225"
     misc_feature    complement(222148..222165)
                     /gene="metN"
                     /locus_tag="b0199"
                     /gene_synonym="abc; ECK0199; JW0195; metD"
                     /note="Walker B; other site"
                     /db_xref="CDD:213225"
     misc_feature    complement(222130..222141)
                     /gene="metN"
                     /locus_tag="b0199"
                     /gene_synonym="abc; ECK0199; JW0195; metD"
                     /note="D-loop; other site"
                     /db_xref="CDD:213225"
     misc_feature    complement(222043..222063)
                     /gene="metN"
                     /locus_tag="b0199"
                     /gene_synonym="abc; ECK0199; JW0195; metD"
                     /note="H-loop/switch region; other site"
                     /db_xref="CDD:213225"
     misc_feature    complement(221626..221847)
                     /gene="metN"
                     /locus_tag="b0199"
                     /gene_synonym="abc; ECK0199; JW0195; metD"
                     /note="This domain is found at the C-terminus of ABC
                     transporter proteins involved in D-methionine transport as
                     well as a number of ferredoxin-like proteins; Region: NIL;
                     smart00930"
                     /db_xref="CDD:197998"
     gene            222833..223408
                     /gene="gmhB"
                     /locus_tag="b0200"
                     /gene_synonym="ECK0200; gmbC; gmbX; gmhX; JW0196; wcbN;
                     yaeD"
                     /db_xref="EcoGene:EG11736"
                     /db_xref="GeneID:944879"
     CDS             222833..223408
                     /gene="gmhB"
                     /locus_tag="b0200"
                     /gene_synonym="ECK0200; gmbC; gmbX; gmhX; JW0196; wcbN;
                     yaeD"
                     /function="enzyme; Surface polysaccharides and antigens"
                     /codon_start=1
                     /transl_table=11
                     /product="D,D-heptose 1,7-bisphosphate phosphatase"
                     /protein_id="NP_414742.1"
                     /db_xref="GI:16128193"
                     /db_xref="ASAP:ABE-0000675"
                     /db_xref="UniProtKB/Swiss-Prot:P63228"
                     /db_xref="EcoGene:EG11736"
                     /db_xref="GeneID:944879"
                     /translation="MAKSVPAIFLDRDGTINVDHGYVHEIDNFEFIDGVIDAMRELKK
                     MGFALVVVTNQSGIARGKFTEAQFETLTEWMDWSLADRDVDLDGIYYCPHHPQGSVEE
                     FRQVCDCRKPHPGMLLSARDYLHIDMAASYMVGDKLEDMQAAVAANVGTKVLVRTGKP
                     ITPEAENAADWVLNSLADLPQAIKKQQKPAQ"
     misc_feature    222845..223375
                     /gene="gmhB"
                     /locus_tag="b0200"
                     /gene_synonym="ECK0200; gmbC; gmbX; gmhX; JW0196; wcbN;
                     yaeD"
                     /note="D,D-heptose 1,7-bisphosphate phosphatase; Region:
                     GmhB_yaeD; TIGR00213"
                     /db_xref="CDD:129317"
     misc_feature    222851..223297
                     /gene="gmhB"
                     /locus_tag="b0200"
                     /gene_synonym="ECK0200; gmbC; gmbX; gmhX; JW0196; wcbN;
                     yaeD"
                     /note="Haloacid dehalogenase-like hydrolases. The haloacid
                     dehalogenase-like (HAD) superfamily includes L-2-haloacid
                     dehalogenase, epoxide hydrolase, phosphoserine
                     phosphatase, phosphomannomutase, phosphoglycolate
                     phosphatase, P-type ATPase, and many others; Region:
                     HAD_like; cd01427"
                     /db_xref="CDD:119389"
     misc_feature    order(222863..222871,222989..222994)
                     /gene="gmhB"
                     /locus_tag="b0200"
                     /gene_synonym="ECK0200; gmbC; gmbX; gmhX; JW0196; wcbN;
                     yaeD"
                     /note="active site"
                     /db_xref="CDD:119389"
     misc_feature    222863..222880
                     /gene="gmhB"
                     /locus_tag="b0200"
                     /gene_synonym="ECK0200; gmbC; gmbX; gmhX; JW0196; wcbN;
                     yaeD"
                     /note="motif I; other site"
                     /db_xref="CDD:119389"
     misc_feature    222989..222991
                     /gene="gmhB"
                     /locus_tag="b0200"
                     /gene_synonym="ECK0200; gmbC; gmbX; gmhX; JW0196; wcbN;
                     yaeD"
                     /note="motif II; other site"
                     /db_xref="CDD:119389"
     gene            223771..225312
                     /gene="rrsH"
                     /locus_tag="b0201"
                     /gene_synonym="ECK0201; JWR0001"
                     /db_xref="EcoGene:EG30090"
                     /db_xref="GeneID:944897"
     rRNA            223771..225312
                     /gene="rrsH"
                     /locus_tag="b0201"
                     /gene_synonym="ECK0201; JWR0001"
                     /product="16S ribosomal RNA of rrnH operon"
                     /db_xref="ASAP:ABE-0000677"
                     /db_xref="EcoGene:EG30090"
                     /db_xref="GeneID:944897"
     gene            225381..225457
                     /gene="ileV"
                     /locus_tag="b0202"
                     /gene_synonym="ECK0202; JWR0002"
                     /db_xref="EcoGene:EG30045"
                     /db_xref="GeneID:944884"
     tRNA            225381..225457
                     /gene="ileV"
                     /locus_tag="b0202"
                     /gene_synonym="ECK0202; JWR0002"
                     /product="tRNA-Ile"
                     /note="anticodon: GAU"
                     /db_xref="ASAP:ABE-0000679"
                     /db_xref="EcoGene:EG30045"
                     /db_xref="GeneID:944884"
     gene            225500..225575
                     /gene="alaV"
                     /locus_tag="b0203"
                     /gene_synonym="ECK0203; JWR0003"
                     /db_xref="EcoGene:EG30010"
                     /db_xref="GeneID:944890"
     tRNA            225500..225575
                     /gene="alaV"
                     /locus_tag="b0203"
                     /gene_synonym="ECK0203; JWR0003"
                     /product="tRNA-Ala"
                     /note="anticodon: UGC"
                     /db_xref="ASAP:ABE-0000682"
                     /db_xref="EcoGene:EG30010"
                     /db_xref="GeneID:944890"
     gene            225759..228662
                     /gene="rrlH"
                     /locus_tag="b0204"
                     /gene_synonym="ECK0204; JWR0004"
                     /db_xref="EcoGene:EG30083"
                     /db_xref="GeneID:944900"
     rRNA            225759..228662
                     /gene="rrlH"
                     /locus_tag="b0204"
                     /gene_synonym="ECK0204; JWR0004"
                     /product="23S ribosomal RNA of rrnH operon"
                     /db_xref="ASAP:ABE-0000684"
                     /db_xref="EcoGene:EG30083"
                     /db_xref="GeneID:944900"
     gene            228756..228875
                     /gene="rrfH"
                     /locus_tag="b0205"
                     /gene_synonym="ECK0205; JWR0005"
                     /db_xref="EcoGene:EG30076"
                     /db_xref="GeneID:944898"
     rRNA            228756..228875
                     /gene="rrfH"
                     /locus_tag="b0205"
                     /gene_synonym="ECK0205; JWR0005"
                     /product="5S ribosomal RNA of rrnH operon"
                     /db_xref="ASAP:ABE-0000686"
                     /db_xref="EcoGene:EG30076"
                     /db_xref="GeneID:944898"
     gene            228928..229004
                     /gene="aspU"
                     /locus_tag="b0206"
                     /gene_synonym="ECK0206; JWR0006"
                     /db_xref="EcoGene:EG30024"
                     /db_xref="GeneID:944880"
     tRNA            228928..229004
                     /gene="aspU"
                     /locus_tag="b0206"
                     /gene_synonym="ECK0206; JWR0006"
                     /product="tRNA-Asp"
                     /note="anticodon: GUC"
                     /db_xref="ASAP:ABE-0000688"
                     /db_xref="EcoGene:EG30024"
                     /db_xref="GeneID:944880"
     gene            229167..229970
                     /gene="dkgB"
                     /locus_tag="b0207"
                     /gene_synonym="ECK0207; JW0197; yafB"
                     /db_xref="EcoGene:EG11648"
                     /db_xref="GeneID:944901"
     CDS             229167..229970
                     /gene="dkgB"
                     /locus_tag="b0207"
                     /gene_synonym="ECK0207; JW0197; yafB"
                     /EC_number="1.1.1.274"
                     /function="putative enzyme; Not classified"
                     /GO_component="GO:0005737 - cytoplasm"
                     /GO_process="GO:0016052 - carbohydrate catabolic process"
                     /codon_start=1
                     /transl_table=11
                     /product="2,5-diketo-D-gluconate reductase B"
                     /protein_id="NP_414743.1"
                     /db_xref="GI:16128194"
                     /db_xref="ASAP:ABE-0000692"
                     /db_xref="UniProtKB/Swiss-Prot:P30863"
                     /db_xref="EcoGene:EG11648"
                     /db_xref="GeneID:944901"
                     /translation="MAIPAFGLGTFRLKDDVVISSVITALELGYRAIDTAQIYDNEAA
                     VGQAIAESGVPRHELYITTKIWIENLSKDKLIPSLKESLQKLRTDYVDLTLIHWPSPN
                     DEVSVEEFMQALLEAKKQGLTREIGISNFTIPLMEKAIAAVGAENIATNQIELSPYLQ
                     NRKVVAWAKQHGIHITSYMTLAYGKALKDEVIARIAAKHNATPAQVILAWAMGEGYSV
                     IPSSTKRKNLESNLKAQNLQLDAEDKKAIAALDCNDRLVSPEGLAPEWD"
     misc_feature    229173..229916
                     /gene="dkgB"
                     /locus_tag="b0207"
                     /gene_synonym="ECK0207; JW0197; yafB"
                     /note="Aldo-keto reductases (AKRs) are a superfamily of
                     soluble NAD(P)(H) oxidoreductases whose chief purpose is
                     to reduce aldehydes and ketones to primary and secondary
                     alcohols. AKRs are present in all phyla and are of
                     importance to both health and industrial...; Region:
                     Aldo_ket_red; cd06660"
                     /db_xref="CDD:119408"
     misc_feature    229173..229883
                     /gene="dkgB"
                     /locus_tag="b0207"
                     /gene_synonym="ECK0207; JW0197; yafB"
                     /note="voltage-dependent potassium channel beta subunit,
                     animal; Region: Kv_beta; TIGR01293"
                     /db_xref="CDD:213602"
     misc_feature    order(229191..229199,229266..229268,229281..229283,
                     229356..229358,229455..229460,229551..229556,
                     229620..229622,229698..229715,229776..229778,
                     229821..229832,229845..229847,229854..229859)
                     /gene="dkgB"
                     /locus_tag="b0207"
                     /gene_synonym="ECK0207; JW0197; yafB"
                     /note="active site"
                     /db_xref="CDD:119408"
     misc_feature    order(229266..229268,229281..229283,229356..229358,
                     229455..229457)
                     /gene="dkgB"
                     /locus_tag="b0207"
                     /gene_synonym="ECK0207; JW0197; yafB"
                     /note="catalytic tetrad [active]"
                     /db_xref="CDD:119408"
     gene            complement(229967..230881)
                     /gene="yafC"
                     /locus_tag="b0208"
                     /gene_synonym="ECK0208; JW0198"
                     /db_xref="EcoGene:EG11649"
                     /db_xref="GeneID:947507"
     CDS             complement(229967..230881)
                     /gene="yafC"
                     /locus_tag="b0208"
                     /gene_synonym="ECK0208; JW0198"
                     /function="putative transport; Not classified"
                     /GO_function="GO:0016563 - transcription activator
                     activity"
                     /GO_function="GO:0016564 - transcription repressor
                     activity"
                     /GO_process="GO:0006350 - transcription"
                     /note="putative transcriptional regulator LYSR-type"
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family putative transcriptional regulator"
                     /protein_id="NP_414744.1"
                     /db_xref="GI:16128195"
                     /db_xref="ASAP:ABE-0000694"
                     /db_xref="UniProtKB/Swiss-Prot:P30864"
                     /db_xref="EcoGene:EG11649"
                     /db_xref="GeneID:947507"
                     /translation="MKATSEELAIFVSVVESGSFSRAAEQLGQANSAVSRAVKKLEMK
                     LGVSLLNRTTRQLSLTEEGERYFRRVQSILQEMAAAESEIMETRNTPRGLLRIDAATP
                     VVLHFLMPLIKPFRERYPEVTLSLVSSETIINLIERKVDVAIRAGTLTDSSLRARPLF
                     NSYRKIIASPDYISRYGKPETIDDLKQHICLGFTEPASLNTWPIARSDGQLHEVKYGL
                     SSNSGETLKQLCLSGNGIACLSDYMIDKEIARGELVELMADKVLPVEMPFSAVYYSDR
                     AVSTRIRAFIDFLSEHVKTAPGGAVREA"
     misc_feature    complement(230000..230866)
                     /gene="yafC"
                     /locus_tag="b0208"
                     /gene_synonym="ECK0208; JW0198"
                     /note="Transcriptional regulator [Transcription]; Region:
                     LysR; COG0583"
                     /db_xref="CDD:223656"
     misc_feature    complement(230690..230860)
                     /gene="yafC"
                     /locus_tag="b0208"
                     /gene_synonym="ECK0208; JW0198"
                     /note="Bacterial regulatory helix-turn-helix protein, lysR
                     family; Region: HTH_1; pfam00126"
                     /db_xref="CDD:249610"
     misc_feature    complement(230015..230611)
                     /gene="yafC"
                     /locus_tag="b0208"
                     /gene_synonym="ECK0208; JW0198"
                     /note="The C-terminal substrate binding domain of
                     LysR-type transcriptional regulator CrgA, contains the
                     type 2 periplasmic binding domain; Region: PBP2_CrgA;
                     cd08478"
                     /db_xref="CDD:176167"
     misc_feature    complement(order(230078..230080,230162..230164,
                     230213..230215,230396..230398,230402..230404,
                     230444..230446,230561..230563,230573..230575))
                     /gene="yafC"
                     /locus_tag="b0208"
                     /gene_synonym="ECK0208; JW0198"
                     /note="putative effector binding pocket; other site"
                     /db_xref="CDD:176167"
     misc_feature    complement(order(230186..230188,230195..230200,
                     230219..230233,230315..230317,230498..230518,
                     230522..230524,230534..230536,230543..230548,
                     230552..230557,230567..230572))
                     /gene="yafC"
                     /locus_tag="b0208"
                     /gene_synonym="ECK0208; JW0198"
                     /note="dimerization interface [polypeptide binding]; other
                     site"
                     /db_xref="CDD:176167"
     gene            231122..231922
                     /gene="yafD"
                     /locus_tag="b0209"
                     /gene_synonym="ECK0209; JW5017"
                     /db_xref="EcoGene:EG11650"
                     /db_xref="GeneID:946286"
     CDS             231122..231922
                     /gene="yafD"
                     /locus_tag="b0209"
                     /gene_synonym="ECK0209; JW5017"
                     /codon_start=1
                     /transl_table=11
                     /product="endo/exonuclease/phosphatase family protein"
                     /protein_id="NP_414745.1"
                     /db_xref="GI:16128196"
                     /db_xref="ASAP:ABE-0000700"
                     /db_xref="UniProtKB/Swiss-Prot:P0A8U2"
                     /db_xref="EcoGene:EG11650"
                     /db_xref="GeneID:946286"
                     /translation="MRKNTYAMRYVAGQPAERILPPGSFASIGQALPPGEPLSTEERI
                     RILVWNIYKQQRAEWLSVLKNYGKDAHLVLLQEAQTTPELVQFATANYLAADQVPAFV
                     LPQHPSGVMTLSAAHPVYCCPLREREPILRLAKSALVTVYPLPDTRLLMVVNIHAVNF
                     SLGVDVYSKQLLPIGDQIAHHSGPVIMAGDFNAWSRRRMNALYRFAREMSLRQVRFTD
                     DQRRRAFGRPLDFVFYRGLNVSEASVLVTRASDHNPLLVEFSPGKPDK"
     misc_feature    231122..231910
                     /gene="yafD"
                     /locus_tag="b0209"
                     /gene_synonym="ECK0209; JW5017"
                     /note="hypothetical protein; Provisional; Region:
                     PRK05421"
                     /db_xref="CDD:235454"
     misc_feature    order(231269..231271,231350..231352,231587..231589,
                     231689..231691,231695..231697)
                     /gene="yafD"
                     /locus_tag="b0209"
                     /gene_synonym="ECK0209; JW5017"
                     /note="putative catalytic site [active]"
                     /db_xref="CDD:197306"
     misc_feature    231350..231352
                     /gene="yafD"
                     /locus_tag="b0209"
                     /gene_synonym="ECK0209; JW5017"
                     /note="putative metal binding site [ion binding]; other
                     site"
                     /db_xref="CDD:197306"
     misc_feature    order(231587..231589,231695..231697)
                     /gene="yafD"
                     /locus_tag="b0209"
                     /gene_synonym="ECK0209; JW5017"
                     /note="putative phosphate binding site [ion binding];
                     other site"
                     /db_xref="CDD:197306"
     misc_feature    order(231689..231691,231695..231697,231809..231811,
                     231872..231877)
                     /gene="yafD"
                     /locus_tag="b0209"
                     /gene_synonym="ECK0209; JW5017"
                     /note="putative catalytic site [active]"
                     /db_xref="CDD:197306"
     misc_feature    order(231695..231697,231875..231877)
                     /gene="yafD"
                     /locus_tag="b0209"
                     /gene_synonym="ECK0209; JW5017"
                     /note="putative phosphate binding site [ion binding];
                     other site"
                     /db_xref="CDD:197306"
     misc_feature    231872..231874
                     /gene="yafD"
                     /locus_tag="b0209"
                     /gene_synonym="ECK0209; JW5017"
                     /note="putative metal binding site [ion binding]; other
                     site"
                     /db_xref="CDD:197306"
     gene            231926..232549
                     /gene="yafE"
                     /locus_tag="b0210"
                     /gene_synonym="ECK0210; JW0200"
                     /db_xref="EcoGene:EG11651"
                     /db_xref="GeneID:946197"
     CDS             231926..232549
                     /gene="yafE"
                     /locus_tag="b0210"
                     /gene_synonym="ECK0210; JW0200"
                     /function="putative enzyme; Not classified"
                     /GO_process="GO:0009102 - biotin biosynthetic process"
                     /note="putative biotin synthesis protein"
                     /codon_start=1
                     /transl_table=11
                     /product="putative S-adenosyl-L-methionine-dependent
                     methyltransferase"
                     /protein_id="NP_414746.1"
                     /db_xref="GI:16128197"
                     /db_xref="ASAP:ABE-0000702"
                     /db_xref="UniProtKB/Swiss-Prot:P30866"
                     /db_xref="EcoGene:EG11651"
                     /db_xref="GeneID:946197"
                     /translation="MSGLPQGRPTFGAAQNVSAVVAYDLSAHMLDVVAQAAEARQLKN
                     ITTRQGYAESLPFADNAFDIVISRYSAHHWHDVGAALREVNRILKPGGRLIVMDVMSP
                     GHPVRDIWLQTVEALRDTSHVRNYASGEWLTLINEANLIVDNLITDKLPLEFSSWVAR
                     MRTPEALVDAIRIYQQSASTEVRTYFALQNDGFFTSDIIMVDAHKAA"
     misc_feature    231944..232342
                     /gene="yafE"
                     /locus_tag="b0210"
                     /gene_synonym="ECK0210; JW0200"
                     /note="Methyltransferase domain; Region: Methyltransf_31;
                     pfam13847"
                     /db_xref="CDD:258120"
     misc_feature    231944..232222
                     /gene="yafE"
                     /locus_tag="b0210"
                     /gene_synonym="ECK0210; JW0200"
                     /note="S-adenosylmethionine-dependent methyltransferases
                     (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes
                     that use S-adenosyl-L-methionine (SAM or AdoMet) as a
                     substrate for methyltransfer, creating the product
                     S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases;
                     cd02440"
                     /db_xref="CDD:100107"
     misc_feature    order(231944..231949,231995..232000,232073..232081,
                     232127..232129)
                     /gene="yafE"
                     /locus_tag="b0210"
                     /gene_synonym="ECK0210; JW0200"
                     /note="S-adenosylmethionine binding site [chemical
                     binding]; other site"
                     /db_xref="CDD:100107"
     gene            complement(232597..233955)
                     /gene="mltD"
                     /locus_tag="b0211"
                     /gene_synonym="dniR; ECK0211; JW5018; yafG"
                     /db_xref="EcoGene:EG10246"
                     /db_xref="GeneID:945694"
     CDS             complement(232597..233955)
                     /gene="mltD"
                     /locus_tag="b0211"
                     /gene_synonym="dniR; ECK0211; JW5018; yafG"
                     /EC_number="3.2.1.-"
                     /function="regulator; Energy metabolism, carbon: Anaerobic
                     respiration"
                     /GO_component="GO:0005737 - cytoplasm"
                     /GO_function="GO:0016563 - transcription activator
                     activity"
                     /GO_process="GO:0009061 - anaerobic respiration"
                     /GO_process="GO:0017004 - cytochrome complex assembly"
                     /GO_process="GO:0006350 - transcription"
                     /codon_start=1
                     /transl_table=11
                     /product="putative membrane-bound lytic murein
                     transglycosylase D"
                     /protein_id="NP_414747.1"
                     /db_xref="GI:16128198"
                     /db_xref="ASAP:ABE-0000704"
                     /db_xref="UniProtKB/Swiss-Prot:P0AEZ7"
                     /db_xref="EcoGene:EG10246"
                     /db_xref="GeneID:945694"
                     /translation="MKAKAILLASVLLVGCQSTGNVQQHAQSLSAAGQGEAAKFTSQA
                     RWMDDGTSIAPDGDLWAFIGDELKMGIPENDRIREQKQKYLRNKSYLHDVTLRAEPYM
                     YWIAGQVKKRNMPMELVLLPIVESAFDPHATSGANAAGIWQIIPSTGRNYGLKQTRNY
                     DARRDVVASTTAALNMMQRLNKMFDGDWLLTVAAYNSGEGRVMKAIKTNKARGKSTDF
                     WSLPLPQETKQYVPKMLALSDILKNSKRYGVRLPTTDESRALARVHLSSPVEMAKVAD
                     MAGISVSKLKTFNAGVKGSTLGASGPQYVMVPKKHADQLRESLASGEIAAVQSTLVAD
                     NTPLNSRVYTVRSGDTLSSIASRLGVSTKDLQQWNKLRGSKLKPGQSLTIGAGSSAQR
                     LANNSDSITYRVRKGDSLSSIAKRHGVNIKDVMRWNSDTANLQPGDKLTLFVKNNNMP
                     DS"
     misc_feature    complement(232600..233955)
                     /gene="mltD"
                     /locus_tag="b0211"
                     /gene_synonym="dniR; ECK0211; JW5018; yafG"
                     /note="membrane-bound lytic murein transglycosylase D;
                     Provisional; Region: mltD; PRK10783"
                     /db_xref="CDD:182727"
     misc_feature    complement(233239..233613)
                     /gene="mltD"
                     /locus_tag="b0211"
                     /gene_synonym="dniR; ECK0211; JW5018; yafG"
                     /note="Lytic Transglycosylase (LT)  and Goose Egg White
                     Lysozyme (GEWL) domain. Members include the soluble and
                     insoluble membrane-bound LTs in bacteria, the LTs in
                     bacteriophage lambda, as well as, the eukaryotic
                     'goose-type' lysozymes (GEWL).  LTs...; Region: LT_GEWL;
                     cd00254"
                     /db_xref="CDD:238157"
     misc_feature    complement(order(233371..233373,233428..233430,
                     233521..233523,233581..233583))
                     /gene="mltD"
                     /locus_tag="b0211"
                     /gene_synonym="dniR; ECK0211; JW5018; yafG"
                     /note="N-acetyl-D-glucosamine binding site [chemical
                     binding]; other site"
                     /db_xref="CDD:238157"
     misc_feature    complement(233581..233583)
                     /gene="mltD"
                     /locus_tag="b0211"
                     /gene_synonym="dniR; ECK0211; JW5018; yafG"
                     /note="catalytic residue [active]"
                     /db_xref="CDD:238157"
     misc_feature    complement(232804..232935)
                     /gene="mltD"
                     /locus_tag="b0211"
                     /gene_synonym="dniR; ECK0211; JW5018; yafG"
                     /note="Lysine Motif is a small domain involved in binding
                     peptidoglycan; Region: LysM; cd00118"
                     /db_xref="CDD:212030"
     misc_feature    complement(232630..232758)
                     /gene="mltD"
                     /locus_tag="b0211"
                     /gene_synonym="dniR; ECK0211; JW5018; yafG"
                     /note="Lysine Motif is a small domain involved in binding
                     peptidoglycan; Region: LysM; cd00118"
                     /db_xref="CDD:212030"
     gene            complement(234027..234782)
                     /gene="gloB"
                     /locus_tag="b0212"
                     /gene_synonym="ECK0212; JW0202; yafR"
                     /db_xref="EcoGene:EG13330"
                     /db_xref="GeneID:944902"
     CDS             complement(234027..234782)
                     /gene="gloB"
                     /locus_tag="b0212"
                     /gene_synonym="ECK0212; JW0202; yafR"
                     /function="putative enzyme; Central intermediary
                     metabolism: Pool, multipurpose conversions"
                     /GO_process="GO:0009438 - methylglyoxal metabolic process"
                     /note="probable hydroxyacylglutathione hydrolase"
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxyacylglutathione hydrolase"
                     /protein_id="NP_414748.1"
                     /db_xref="GI:16128199"
                     /db_xref="ASAP:ABE-0000707"
                     /db_xref="UniProtKB/Swiss-Prot:P0AC84"
                     /db_xref="EcoGene:EG13330"
                     /db_xref="GeneID:944902"
                     /translation="MNLNSIPAFDDNYIWVLNDEAGRCLIVDPGDAEPVLNAIAANNW
                     QPEAIFLTHHHHDHVGGVKELVEKFPQIVVYGPQETQDKGTTQVVKDGETAFVLGHEF
                     SVIATPGHTLGHICYFSKPYLFCGDTLFSGGCGRLFEGTASQMYQSLKKLSALPDDTL
                     VCCAHEYTLSNMKFALSILPHDLSINDYYRKVKELRAKNQITLPVILKNERQINVFLR
                     TEDIDLINVINEETLLQQPEERFAWLRSKKDRF"
     misc_feature    complement(234030..234782)
                     /gene="gloB"
                     /locus_tag="b0212"
                     /gene_synonym="ECK0212; JW0202; yafR"
                     /note="hydroxyacylglutathione hydrolase; Provisional;
                     Region: PRK10241"
                     /db_xref="CDD:182327"
     gene            234816..235538
                     /gene="yafS"
                     /locus_tag="b0213"
                     /gene_synonym="ECK0213; JW0203"
                     /db_xref="EcoGene:EG13331"
                     /db_xref="GeneID:944903"
     CDS             234816..235538
                     /gene="yafS"
                     /locus_tag="b0213"
                     /gene_synonym="ECK0213; JW0203"
                     /codon_start=1
                     /transl_table=11
                     /product="putative S-adenosyl-L-methionine-dependent
                     methyltransferase"
                     /protein_id="NP_414749.2"
                     /db_xref="GI:90111099"
                     /db_xref="ASAP:ABE-0000713"
                     /db_xref="UniProtKB/Swiss-Prot:P75672"
                     /db_xref="EcoGene:EG13331"
                     /db_xref="GeneID:944903"
                     /translation="MKPARVPQTVVAPDCWGDLPWGKLYRKALERQLNPWFTKMYGFH
                     LLKIGNLSAEINCEACAVSHQVNVSAQGMPVQVQADPLHLPFADKSVDVCLLAHTLPW
                     CTDPHRLLREADRVLIDDGWLVISGFNPISFMGLRKLVPVLRKTSPYNSRMFTLMRQL
                     DWLSLLNFEVLHASRFHVLPWNKHGGKLLNAHIPALGCLQLIVARKRTIPLTLNPMKQ
                     SKNKPRIRQAVGATRQCRKPQA"
     misc_feature    <234975..235193
                     /gene="yafS"
                     /locus_tag="b0213"
                     /gene_synonym="ECK0213; JW0203"
                     /note="S-adenosylmethionine-dependent methyltransferases
                     (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes
                     that use S-adenosyl-L-methionine (SAM or AdoMet) as a
                     substrate for methyltransfer, creating the product
                     S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases;
                     cd02440"
                     /db_xref="CDD:100107"
     gene            complement(235535..236002)
                     /gene="rnhA"
                     /locus_tag="b0214"
                     /gene_synonym="cer; dasF; ECK0214; herA; JW0204; rnh;
                     sdrA; sin"
                     /db_xref="EcoGene:EG10860"
                     /db_xref="GeneID:946955"
     CDS             complement(235535..236002)
                     /gene="rnhA"
                     /locus_tag="b0214"
                     /gene_synonym="cer; dasF; ECK0214; herA; JW0204; rnh;
                     sdrA; sin"
                     /EC_number="3.1.26.4"
                     /function="enzyme; Degradation of RNA"
                     /experiment="N-terminus verified by Edman degradation:
                     PMID 2171503"
                     /GO_component="GO:0005737 - cytoplasm"
                     /GO_process="GO:0006401 - RNA catabolic process"
                     /GO_process="GO:0006261 - DNA-dependent DNA replication"
                     /GO_process="GO:0006508 - proteolysis"
                     /note="RNase HI, degrades RNA of DNA-RNA hybrids,
                     participates in DNA replication"
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease HI, degrades RNA of DNA-RNA
                     hybrids"
                     /protein_id="NP_414750.1"
                     /db_xref="GI:16128201"
                     /db_xref="ASAP:ABE-0000717"
                     /db_xref="UniProtKB/Swiss-Prot:P0A7Y4"
                     /db_xref="EcoGene:EG10860"
                     /db_xref="GeneID:946955"
                     /translation="MLKQVEIFTDGSCLGNPGPGGYGAILRYRGREKTFSAGYTRTTN
                     NRMELMAAIVALEALKEHCEVILSTDSQYVRQGITQWIHNWKKRGWKTADKKPVKNVD
                     LWQRLDAALGQHQIKWEWVKGHAGHPENERCDELARAAAMNPTLEDTGYQVEV"
     misc_feature    complement(235580..235993)
                     /gene="rnhA"
                     /locus_tag="b0214"
                     /gene_synonym="cer; dasF; ECK0214; herA; JW0204; rnh;
                     sdrA; sin"
                     /note="RNase HI family found mainly in prokaryotes;
                     Region: RNase_HI_prokaryote_like; cd09278"
                     /db_xref="CDD:260010"
     misc_feature    complement(order(235589..235591,235643..235645,
                     235793..235795,235859..235861,235868..235876,
                     235964..235975))
                     /gene="rnhA"
                     /locus_tag="b0214"
                     /gene_synonym="cer; dasF; ECK0214; herA; JW0204; rnh;
                     sdrA; sin"
                     /note="RNA/DNA hybrid binding site [nucleotide binding];
                     other site"
                     /db_xref="CDD:260010"
     misc_feature    complement(order(235601..235603,235793..235795,
                     235859..235861,235973..235975))
                     /gene="rnhA"
                     /locus_tag="b0214"
                     /gene_synonym="cer; dasF; ECK0214; herA; JW0204; rnh;
                     sdrA; sin"
                     /note="active site"
                     /db_xref="CDD:260010"
     gene            236067..236798
                     /gene="dnaQ"
                     /locus_tag="b0215"
                     /gene_synonym="ECK0215; JW0205; mutD"
                     /db_xref="EcoGene:EG10243"
                     /db_xref="GeneID:946441"
     CDS             236067..236798
                     /gene="dnaQ"
                     /locus_tag="b0215"
                     /gene_synonym="ECK0215; JW0205; mutD"
                     /EC_number="2.7.7.7"
                     /function="enzyme; DNA - replication, repair,
                     restriction/modification"
                     /GO_component="GO:0005737 - cytoplasm"
                     /GO_process="GO:0006261 - DNA-dependent DNA replication"
                     /GO_process="GO:0006457 - protein folding"
                     /note="DNA polymerase III, epsilon subunit"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III epsilon subunit"
                     /protein_id="NP_414751.1"
                     /db_xref="GI:16128202"
                     /db_xref="ASAP:ABE-0000722"
                     /db_xref="UniProtKB/Swiss-Prot:P03007"
                     /db_xref="EcoGene:EG10243"
                     /db_xref="GeneID:946441"
                     /translation="MSTAITRQIVLDTETTGMNQIGAHYEGHKIIEIGAVEVVNRRLT
                     GNNFHVYLKPDRLVDPEAFGVHGIADEFLLDKPTFAEVADEFMDYIRGAELVIHNAAF
                     DIGFMDYEFSLLKRDIPKTNTFCKVTDSLAVARKMFPGKRNSLDALCARYEIDNSKRT
                     LHGALLDAQILAEVYLAMTGGQTSMAFAMEGETQQQQGEATIQRIVRQASKLRVVFAT
                     DEEIAAHEARLDLVQKKGGSCLWRA"
     misc_feature    236085..236774
                     /gene="dnaQ"
                     /locus_tag="b0215"
                     /gene_synonym="ECK0215; JW0205; mutD"
                     /note="DNA polymerase III, epsilon subunit,
                     Proteobacterial; Region: dnaQ_proteo; TIGR01406"
                     /db_xref="CDD:130473"
     misc_feature    236088..236603
                     /gene="dnaQ"
                     /locus_tag="b0215"
                     /gene_synonym="ECK0215; JW0205; mutD"
                     /note="DEDDh 3'-5' exonuclease domain of the epsilon
                     subunit of Escherichia coli DNA polymerase III and similar
                     proteins; Region: DNA_pol_III_epsilon_Ecoli_like; cd06131"
                     /db_xref="CDD:99835"
     misc_feature    order(236100..236111,236115..236120,236247..236252,
                     236259..236264,236358..236363,236367..236375,
                     236496..236501,236541..236543,236550..236552,
                     236565..236567)
                     /gene="dnaQ"
                     /locus_tag="b0215"
                     /gene_synonym="ECK0215; JW0205; mutD"
                     /note="active site"
                     /db_xref="CDD:99835"
     misc_feature    order(236100..236111,236115..236120,236247..236252,
                     236259..236264,236358..236363,236367..236372,
                     236496..236501,236541..236543,236550..236552,
                     236565..236567)
                     /gene="dnaQ"
                     /locus_tag="b0215"
                     /gene_synonym="ECK0215; JW0205; mutD"
                     /note="substrate binding site [chemical binding]; other
                     site"
                     /db_xref="CDD:99835"
     misc_feature    order(236100..236102,236106..236108,236373..236375,
                     236550..236552,236565..236567)
                     /gene="dnaQ"
                     /locus_tag="b0215"
                     /gene_synonym="ECK0215; JW0205; mutD"
                     /note="catalytic site [active]"
                     /db_xref="CDD:99835"
     gene            236931..237007
                     /gene="aspV"
                     /locus_tag="b0216"
                     /gene_synonym="ECK0216; JWR0007"
                     /db_xref="EcoGene:EG30025"
                     /db_xref="GeneID:947541"
     tRNA            236931..237007
                     /gene="aspV"
                     /locus_tag="b0216"
                     /gene_synonym="ECK0216; JWR0007"
                     /product="tRNA-Asp"
                     /note="anticodon: GUC"
                     /db_xref="ASAP:ABE-0000724"
                     /db_xref="EcoGene:EG30025"
                     /db_xref="GeneID:947541"
     gene            237335..238120
                     /gene="yafT"
                     /locus_tag="b0217"
                     /gene_synonym="ECK0217; JW0206"
                     /db_xref="EcoGene:EG13332"
                     /db_xref="GeneID:949009"
     CDS             237335..238120
                     /gene="yafT"
                     /locus_tag="b0217"
                     /gene_synonym="ECK0217; JW0206"
                     /function="putative enzyme; Not classified"
                     /note="putative aminopeptidase"
                     /codon_start=1
                     /transl_table=11
                     /product="lipoprotein"
                     /protein_id="NP_414752.1"
                     /db_xref="GI:16128203"
                     /db_xref="ASAP:ABE-0000727"
                     /db_xref="UniProtKB/Swiss-Prot:P77339"
                     /db_xref="EcoGene:EG13332"
                     /db_xref="GeneID:949009"
                     /translation="MNSKKLCCICVLFSLLAGCASESSIDEKKKKAQVTQSNINKNTP
                     QQLTDKDLFGNETTLAVSEEDIQAALDGDEFRVPLNSPVILVQSGNRAPETIMQEEMR
                     KYYTVSTFSGIPDRQKPLTCNKNKDKNENEDVASAENMNWMQALRFVAAKGHQKAIIV
                     YQDMLQTGKYDSALKSTVWSDYKNDKLTDAISLRYLVRFTLVDVATGEWATWSPVNYE
                     YKVLPPLPDKNEASTTDMTEQQIMQLKQKTYKAMVKDLVNRYQ"
     gene            complement(238257..238736)
                     /gene="ykfM"
                     /locus_tag="b4586"
                     /gene_synonym="ECK4397"
                     /db_xref="EcoGene:EG14451"
                     /db_xref="GeneID:5061498"
     CDS             complement(238257..238736)
                     /gene="ykfM"
                     /locus_tag="b4586"
                     /gene_synonym="ECK4397"
                     /codon_start=1
                     /transl_table=11
                     /product="lethality reduction protein, putative inner
                     membrane protein"
                     /protein_id="YP_001165307.1"
                     /db_xref="GI:145698220"
                     /db_xref="UniProtKB/Swiss-Prot:A5A605"
                     /db_xref="EcoGene:EG14451"
                     /db_xref="GeneID:5061498"
                     /translation="MRLHVKLKEFLSMFFMAILFFPAFNASLFFTGVKPLYSIIKCST
                     EIFYDWRMLILCFGFMSFSFLNIHVILLTIIKSFLIKKTKVVNFATDITIQLTLIFLL
                     IAIVIAPLIAPFVTGYVNTNYHPCGNNTGIFPGAIYIKNGMKCNNGYISRKEDSAVK"
     gene            complement(238746..239102)
                     /gene="yafU"
                     /locus_tag="b0218"
                     /gene_synonym="ECK0218; JW0207"
                     /pseudo
                     /db_xref="EcoGene:EG13333"
                     /db_xref="GeneID:946644"
     CDS             complement(238746..239102)
                     /gene="yafU"
                     /locus_tag="b0218"
                     /gene_synonym="ECK0218; JW0207"
                     /note="pseudogene"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /db_xref="ASAP:ABE-0000729"
                     /db_xref="UniProtKB/Swiss-Prot:P77354"
                     /db_xref="EcoGene:EG13333"
                     /db_xref="GeneID:946644"
     gene            239106..239378
                     /gene="yafF"
                     /locus_tag="b4503"
                     /gene_synonym="ECK0219; JW0208"
                     /pseudo
                     /db_xref="EcoGene:EG11772"
                     /db_xref="GeneID:1450235"
     CDS             239106..239378
                     /gene="yafF"
                     /locus_tag="b4503"
                     /gene_synonym="ECK0219; JW0208"
                     /GO_component="GO:0005737 - cytoplasm"
                     /note="pseudogene, H repeat-associated protein"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /db_xref="ASAP:ABE-0285024"
                     /db_xref="UniProtKB/Swiss-Prot:Q2EEP9"
                     /db_xref="EcoGene:EG11772"
                     /db_xref="GeneID:1450235"
     gene            complement(239419..240189)
                     /gene="yafV"
                     /locus_tag="b0219"
                     /gene_synonym="ECK0220; JW5019"
                     /db_xref="EcoGene:EG13334"
                     /db_xref="GeneID:946585"
     CDS             complement(239419..240189)
                     /gene="yafV"
                     /locus_tag="b0219"
                     /gene_synonym="ECK0220; JW5019"
                     /function="putative enzyme; Not classified"
                     /note="putative EC 3.5. amidase-type enzyme"
                     /codon_start=1
                     /transl_table=11
                     /product="putative NAD(P)-binding C-N hydrolase family
                     amidase"
                     /protein_id="NP_414754.1"
                     /db_xref="GI:16128205"
                     /db_xref="ASAP:ABE-0000734"
                     /db_xref="UniProtKB/Swiss-Prot:Q47679"
                     /db_xref="EcoGene:EG13334"
                     /db_xref="GeneID:946585"
                     /translation="MPGLKITLLQQPLVWMDGPANLRHFDRQLEGITGRDVIVLPEMF
                     TSGFAMEAAASSLAQDDVVNWMTAKAQQCNALIAGSVALQTESGSVNRFLLVEPGGTV
                     HFYDKRHLFRMADEHLHYKAGNARVIVEWRGWRILPLVCYDLRFPVWSRNLNDYDLAL
                     YVANWPAPRSLHWQALLTARAIENQAYVAGCNRVGSDGNGCHYRGDSRVINPQGEIIA
                     TADAHQATRIDAELSMAALREYREKFPAWQDADEFRLW"
     misc_feature    complement(239431..240180)
                     /gene="yafV"
                     /locus_tag="b0219"
                     /gene_synonym="ECK0220; JW5019"
                     /note="Xanthomonas campestris XC1258 and related proteins,
                     members of the nitrilase superfamily (putative class 13
                     nitrilases); Region: Xc-1258_like; cd07575"
                     /db_xref="CDD:143599"
     misc_feature    complement(order(239695..239700,239755..239760,
                     239764..239769,239842..239844,239857..239859,
                     239869..239871,240046..240048,240064..240066))
                     /gene="yafV"
                     /locus_tag="b0219"
                     /gene_synonym="ECK0220; JW5019"
                     /note="putative active site [active]"
                     /db_xref="CDD:143599"
     misc_feature    complement(order(239767..239769,239869..239871,
                     240064..240066))
                     /gene="yafV"
                     /locus_tag="b0219"
                     /gene_synonym="ECK0220; JW5019"
                     /note="catalytic triad [active]"
                     /db_xref="CDD:143599"
     misc_feature    complement(order(239431..239448,239452..239463,
                     239500..239502,239506..239511,239515..239517,
                     239527..239553,239557..239559,239641..239646,
                     239650..239658,239662..239667,239674..239679,
                     239737..239739,239743..239757,239764..239766,
                     239851..239853,239863..239868))
                     /gene="yafV"
                     /locus_tag="b0219"
                     /gene_synonym="ECK0220; JW5019"
                     /note="multimer interface [polypeptide binding]; other
                     site"
                     /db_xref="CDD:143599"
     misc_feature    complement(order(239431..239448,239452..239463,
                     239545..239553,239641..239646,239650..239658,
                     239662..239667,239674..239679,239737..239739,
                     239743..239757,239764..239766,239851..239853,
                     239863..239868))
                     /gene="yafV"
                     /locus_tag="b0219"
                     /gene_synonym="ECK0220; JW5019"
                     /note="dimer interface [polypeptide binding]; other site"
                     /db_xref="CDD:143599"
     gene            240343..240816
                     /gene="ivy"
                     /locus_tag="b0220"
                     /gene_synonym="ECK0221; JW0210; ykfE"
                     /db_xref="EcoGene:EG13547"
                     /db_xref="GeneID:946530"
     CDS             240343..240816
                     /gene="ivy"
                     /locus_tag="b0220"
                     /gene_synonym="ECK0221; JW0210; ykfE"
                     /note="inhibitor of vertebrate C-type lysozyme,
                     periplasmic"
                     /codon_start=1
                     /transl_table=11
                     /product="inhibitor of c-type lysozyme, periplasmic"
                     /protein_id="NP_414755.1"
                     /db_xref="GI:16128206"
                     /db_xref="ASAP:ABE-0000740"
                     /db_xref="UniProtKB/Swiss-Prot:P0AD59"
                     /db_xref="EcoGene:EG13547"
                     /db_xref="GeneID:946530"
                     /translation="MGRISSGGMMFKAITTVAALVIATSAMAQDDLTISSLAKGETTK
                     AAFNQMVQGHKLPAWVMKGGTYTPAQTVTLGDETYQVMSACKPHDCGSQRIAVMWSEK
                     SNQMTGLFSTIDEKTSQEKLTWLNVNDALSIDGKTVLFAALTGSLENHPDGFNFK"
     misc_feature    240355..240813
                     /gene="ivy"
                     /locus_tag="b0220"
                     /gene_synonym="ECK0221; JW0210; ykfE"
                     /note="C-lysozyme inhibitor; Provisional; Region:
                     PRK09993"
                     /db_xref="CDD:182187"
     gene            complement(240859..243303)
                     /gene="fadE"
                     /locus_tag="b0221"
                     /gene_synonym="ECK0222; fadF; JW5020; yafH"
                     /db_xref="EcoGene:EG13145"
                     /db_xref="GeneID:949007"
     CDS             complement(240859..243303)
                     /gene="fadE"
                     /locus_tag="b0221"
                     /gene_synonym="ECK0222; fadF; JW5020; yafH"
                     /EC_number="1.3.99.-"
                     /function="putative enzyme; Not classified"
                     /GO_process="GO:0019395 - fatty acid oxidation"
                     /codon_start=1
                     /transl_table=11
                     /product="acyl coenzyme A dehydrogenase"
                     /protein_id="NP_414756.2"
                     /db_xref="GI:90111100"
                     /db_xref="ASAP:ABE-0000743"
                     /db_xref="UniProtKB/Swiss-Prot:Q47146"
                     /db_xref="EcoGene:EG13145"
                     /db_xref="GeneID:949007"
                     /translation="MMILSILATVVLLGALFYHRVSLFISSLILLAWTAALGVAGLWS
                     AWVLVPLAIILVPFNFAPMRKSMISAPVFRGFRKVMPPMSRTEKEAIDAGTTWWEGDL
                     FQGKPDWKKLHNYPQPRLTAEEQAFLDGPVEEACRMANDFQITHELADLPPELWAYLK
                     EHRFFAMIIKKEYGGLEFSAYAQSRVLQKLSGVSGILAITVGVPNSLGPGELLQHYGT
                     DEQKDHYLPRLARGQEIPCFALTSPEAGSDAGAIPDTGIVCMGEWQGQQVLGMRLTWN
                     KRYITLAPIATVLGLAFKLSDPEKLLGGAEDLGITCALIPTTTPGVEIGRRHFPLNVP
                     FQNGPTRGKDVFVPIDYIIGGPKMAGQGWRMLVECLSVGRGITLPSNSTGGVKSVALA
                     TGAYAHIRRQFKISIGKMEGIEEPLARIAGNAYVMDAAASLITYGIMLGEKPAVLSAI
                     VKYHCTHRGQQSIIDAMDITGGKGIMLGQSNFLARAYQGAPIAITVEGANILTRSMMI
                     FGQGAIRCHPYVLEEMEAAKNNDVNAFDKLLFKHIGHVGSNKVRSFWLGLTRGLTSST
                     PTGDATKRYYQHLNRLSANLALLSDVSMAVLGGSLKRRERISARLGDILSQLYLASAV
                     LKRYDDEGRNEADLPLVHWGVQDALYQAEQAMDDLLQNFPNRVVAGLLNVVIFPTGRH
                     YLAPSDKLDHKVAKILQVPNATRSRIGRGQYLTPSEHNPVGLLEEALVDVIAADPIHQ
                     RICKELGKNLPFTRLDELAHNALVKGLIDKDEAAILVKAEESRLRSINVDDFDPEELA
                     TKPVKLPEKVRKVEAA"
     misc_feature    complement(240862..243180)
                     /gene="fadE"
                     /locus_tag="b0221"
                     /gene_synonym="ECK0222; fadF; JW5020; yafH"
                     /note="acyl-CoA dehydrogenase; Reviewed; Region: fadE;
                     PRK09463"
                     /db_xref="CDD:236528"
     misc_feature    complement(241804..242850)
                     /gene="fadE"
                     /locus_tag="b0221"
                     /gene_synonym="ECK0222; fadF; JW5020; yafH"
                     /note="Acyl-CoA dehydrogenase; Region: ACAD; cl09933"
                     /db_xref="CDD:263927"
     misc_feature    complement(order(241807..241809,241813..241821,
                     242461..242463,242467..242469,242584..242586,
                     242590..242592,242683..242685))
                     /gene="fadE"
                     /locus_tag="b0221"
                     /gene_synonym="ECK0222; fadF; JW5020; yafH"
                     /note="active site"
                     /db_xref="CDD:173838"
     misc_feature    complement(240928..241764)
                     /gene="fadE"
                     /locus_tag="b0221"
                     /gene_synonym="ECK0222; fadF; JW5020; yafH"
                     /note="Domain of unknown function (DUF1974); Region:
                     DUF1974; pfam09317"
                     /db_xref="CDD:255283"
     gene            243543..244121
                     /gene="gmhA"
                     /locus_tag="b0222"
                     /gene_synonym="ECK0223; isn; JW0212; lpcA; tfrA; yafI"
                     /db_xref="EcoGene:EG13146"
                     /db_xref="GeneID:949134"
     CDS             243543..244121
                     /gene="gmhA"
                     /locus_tag="b0222"
                     /gene_synonym="ECK0223; isn; JW0212; lpcA; tfrA; yafI"
                     /EC_number="5.-.-.-"
                     /function="enzyme; Surface polysaccharides & antigens"
                     /GO_component="GO:0005737 - cytoplasm"
                     /GO_function="GO:0042280 - cell surface antigen activity,
                     host-interacting"
                     /GO_process="GO:0009244 - lipopolysaccharide core region
                     biosynthetic process"
                     /note="phosphoheptose isomerase"
                     /codon_start=1
                     /transl_table=11
                     /product="D-sedoheptulose 7-phosphate isomerase"
                     /protein_id="NP_414757.1"
                     /db_xref="GI:16128208"
                     /db_xref="ASAP:ABE-0000751"
                     /db_xref="UniProtKB/Swiss-Prot:P63224"
                     /db_xref="EcoGene:EG13146"
                     /db_xref="GeneID:949134"
                     /translation="MYQDLIRNELNEAAETLANFLKDDANIHAIQRAAVLLADSFKAG
                     GKVLSCGNGGSHCDAMHFAEELTGRYRENRPGYPAIAISDVSHISCVGNDFGFNDIFS
                     RYVEAVGREGDVLLGISTSGNSANVIKAIAAAREKGMKVITLTGKDGGKMAGTADIEI
                     RVPHFGYADRIQEIHIKVIHILIQLIEKEMVK"
     misc_feature    243570..244106
                     /gene="gmhA"
                     /locus_tag="b0222"
                     /gene_synonym="ECK0223; isn; JW0212; lpcA; tfrA; yafI"
                     /note="Phosphoheptose isomerase is a member of the SIS
                     (Sugar ISomerase) superfamily. Phosphoheptose isomerase
                     catalyzes the isomerization of sedoheptulose 7-phosphate
                     into D-glycero-D-mannoheptose 7-phosphate. This is the
                     first step of the biosynthesis of...; Region: SIS_GmhA;
                     cd05006"
                     /db_xref="CDD:240139"
     misc_feature    order(243579..243581,243591..243593,243633..243635,
                     243642..243644,243702..243704,243720..243725,
                     244056..244061,244071..244073,244080..244082,
                     244092..244094,244104..244106)
                     /gene="gmhA"
                     /locus_tag="b0222"
                     /gene_synonym="ECK0223; isn; JW0212; lpcA; tfrA; yafI"
                     /note="dimer interface [polypeptide binding]; other site"
                     /db_xref="CDD:240139"
     misc_feature    order(243696..243704,243897..243905,243912..243914,
                     244041..244043,244056..244058)
                     /gene="gmhA"
                     /locus_tag="b0222"
                     /gene_synonym="ECK0223; isn; JW0212; lpcA; tfrA; yafI"
                     /note="active site"
                     /db_xref="CDD:240139"
     repeat_region   244129..244263
                     /note="REP17 (repetitive extragenic palindromic) element;
                     contains 3 REP sequences"
     gene            244327..245094
                     /gene="yafJ"
                     /locus_tag="b0223"
                     /gene_synonym="ECK0224; JW0213"
                     /db_xref="EcoGene:EG13147"
                     /db_xref="GeneID:944906"
     CDS             244327..245094
                     /gene="yafJ"
                     /locus_tag="b0223"
                     /gene_synonym="ECK0224; JW0213"
                     /function="putative enzyme; Not classified"
                     /note="putative amidotransferase"
                     /codon_start=1
                     /transl_table=11
                     /product="type 2 glutamine amidotransferase family
                     protein"
                     /protein_id="NP_414758.1"
                     /db_xref="GI:16128209"
                     /db_xref="ASAP:ABE-0000755"
                     /db_xref="UniProtKB/Swiss-Prot:Q47147"
                     /db_xref="EcoGene:EG13147"
                     /db_xref="GeneID:944906"
                     /translation="MCELLGMSANVPTDICFSFTGLVQRGGGTGPHKDGWGITFYEGK
                     GCRTFKDPQPSFNSPIAKLVQDYPIKSCSVVAHIRQANRGEVALENTHPFTRELWGRN
                     WTYAHNGQLTGYKSLETGNFRPVGETDSEKAFCWLLHKLTQRYPRTPGNMAAVFKYIA
                     SLADELRQKGVFNMLLSDGRYVMAYCSTNLHWITRRAPFGVATLLDQDVEIDFSSQTT
                     PNDVVTVIATQPLTGNETWQKIMPGEWRLFCLGERVV"
     misc_feature    244327..245079
                     /gene="yafJ"
                     /locus_tag="b0223"
                     /gene_synonym="ECK0224; JW0213"
                     /note="Glutamine amidotransferases class-II
                     (Gn-AT)_YafJ-type.  YafJ is a glutamine
                     amidotransferase-like protein of unknown function found in
                     prokaryotes, eukaryotes and archaea.  YafJ has a conserved
                     structural fold similar to those of other class II...;
                     Region: YafJ; cd01908"
                     /db_xref="CDD:238889"
     misc_feature    order(244330..244332,244561..244563,244648..244656,
                     244711..244713)
                     /gene="yafJ"
                     /locus_tag="b0223"
                     /gene_synonym="ECK0224; JW0213"
                     /note="putative active site [active]"
                     /db_xref="CDD:238889"
     misc_feature    244348..244977
                     /gene="yafJ"
                     /locus_tag="b0223"
                     /gene_synonym="ECK0224; JW0213"
                     /note="Glutamine amidotransferases class-II; Region:
                     GATase_2; pfam00310"
                     /db_xref="CDD:249761"
     misc_feature    order(244465..244467,244474..244479,244612..244614,
                     244684..244689,244750..244752)
                     /gene="yafJ"
                     /locus_tag="b0223"
                     /gene_synonym="ECK0224; JW0213"
                     /note="putative dimer interface [polypeptide binding];
                     other site"
                     /db_xref="CDD:238889"
     gene            complement(245065..245805)
                     /gene="yafK"
                     /locus_tag="b0224"
                     /gene_synonym="ECK0225; JW0214"
                     /db_xref="EcoGene:EG13148"
                     /db_xref="GeneID:944910"
     CDS             complement(245065..245805)
                     /gene="yafK"
                     /locus_tag="b0224"
                     /gene_synonym="ECK0225; JW0214"
                     /codon_start=1
                     /transl_table=11
                     /product="L,D-transpeptidase-related protein"
                     /protein_id="NP_414759.1"
                     /db_xref="GI:16128210"
                     /db_xref="ASAP:ABE-0000757"
                     /db_xref="UniProtKB/Swiss-Prot:P0AA99"
                     /db_xref="EcoGene:EG13148"
                     /db_xref="GeneID:944910"
                     /translation="MRKIALILAMLLIPCVSFAGLLGSSSSTTPVSKEYKQQLMGSPV
                     YIQIFKEERTLDLYVKMGEQYQLLDSYKICKYSGGLGPKQRQGDFKSPEGFYSVQRNQ
                     LKPDSRYYKAINIGFPNAYDRAHGYEGKYLMIHGDCVSIGCYAMTNQGIDEIFQFVTG
                     ALVFGQPSVQVSIYPFRMTDANMKRHKYSNFKDFWEQLKPGYDYFEQTRKPPTVSVVN
                     GRYVVSKPLSHEVVQPQLASNYTLPEAK"
     misc_feature    complement(245068..245805)
                     /gene="yafK"
                     /locus_tag="b0224"
                     /gene_synonym="ECK0225; JW0214"
                     /note="Uncharacterized protein conserved in bacteria
                     [Function unknown]; Region: COG3034"
                     /db_xref="CDD:225577"
     misc_feature    complement(245329..245679)
                     /gene="yafK"
                     /locus_tag="b0224"
                     /gene_synonym="ECK0225; JW0214"
                     /note="L,D-transpeptidase catalytic domain; Region: YkuD;
                     pfam03734"
                     /db_xref="CDD:252135"
     gene            complement(245961..246239)
                     /gene="yafQ"
                     /locus_tag="b0225"
                     /gene_synonym="ECK0226; JW0215"
                     /db_xref="EcoGene:EG13154"
                     /db_xref="GeneID:944911"
     CDS             complement(245961..246239)
                     /gene="yafQ"
                     /locus_tag="b0225"
                     /gene_synonym="ECK0226; JW0215"
                     /codon_start=1
                     /transl_table=11
                     /product="mRNA interferase toxin of toxin-antitoxin pair
                     YafQ/DinJ"
                     /protein_id="NP_414760.1"
                     /db_xref="GI:16128211"
                     /db_xref="ASAP:ABE-0000761"
                     /db_xref="UniProtKB/Swiss-Prot:Q47149"
                     /db_xref="EcoGene:EG13154"
                     /db_xref="GeneID:944911"
                     /translation="MIQRDIEYSGQYSKDVKLAQKRHKDMNKLKYLMTLLINNTLPLP
                     AVYKDHPLQGSWKGYRDAHVEPDWILIYKLTDKLLRFERTGTHAALFG"
     misc_feature    complement(245967..246233)
                     /gene="yafQ"
                     /locus_tag="b0225"
                     /gene_synonym="ECK0226; JW0215"
                     /note="Uncharacterized protein conserved in bacteria
                     [Function unknown]; Region: COG3041"
                     /db_xref="CDD:225583"
     gene            complement(246242..246502)
                     /gene="dinJ"
                     /locus_tag="b0226"
                     /gene_synonym="ECK0227; JW0216; sosA"
                     /db_xref="EcoGene:EG13142"
                     /db_xref="GeneID:944914"
     CDS             complement(246242..246502)
                     /gene="dinJ"
                     /locus_tag="b0226"
                     /gene_synonym="ECK0227; JW0216; sosA"
                     /function="phenotype; Not classified"
                     /GO_process="GO:0006281 - DNA repair"
                     /note="damage-inducible protein J"
                     /codon_start=1
                     /transl_table=11
                     /product="antitoxin of YafQ-DinJ toxin-antitoxin system"
                     /protein_id="NP_414761.1"
                     /db_xref="GI:16128212"
                     /db_xref="ASAP:ABE-0000764"
                     /db_xref="UniProtKB/Swiss-Prot:Q47150"
                     /db_xref="EcoGene:EG13142"
                     /db_xref="GeneID:944914"
                     /translation="MAANAFVRARIDEDLKNQAADVLAGMGLTISDLVRITLTKVARE
                     KALPFDLREPNQLTIQSIKNSEAGIDVHKAKDADDLFDKLGI"
     misc_feature    complement(246251..246493)
                     /gene="dinJ"
                     /locus_tag="b0226"
                     /gene_synonym="ECK0227; JW0216; sosA"
                     /note="RelB antitoxin; Region: RelB; pfam04221"
                     /db_xref="CDD:252459"
     gene            246712..247461
                     /gene="yafL"
                     /locus_tag="b0227"
                     /gene_synonym="ECK0228; JW0217"
                     /db_xref="EcoGene:EG13149"
                     /db_xref="GeneID:944899"
     CDS             246712..247461
                     /gene="yafL"
                     /locus_tag="b0227"
                     /gene_synonym="ECK0228; JW0217"
                     /function="putative membrane; Not classified"
                     /GO_component="GO:0009274 - peptidoglycan-based cell wall"
                     /note="putative lipoprotein"
                     /codon_start=1
                     /transl_table=11
                     /product="putative lipoprotein and C40 family peptidase"
                     /protein_id="NP_414762.1"
                     /db_xref="GI:16128213"
                     /db_xref="ASAP:ABE-0000775"
                     /db_xref="UniProtKB/Swiss-Prot:Q47151"
                     /db_xref="EcoGene:EG13149"
                     /db_xref="GeneID:944899"
                     /translation="MSLPSIPSFVLSGLLLICLPFSSFASATTSHISFSYAARQRMQN
                     RARLLKQYQTHLKKQASYIVEGNAESKRALRQHNREQIKQHPEWFPAPLKASDRRWQA
                     LAENNHFLSSDHLHNITEVAIHRLEQQLGKPYVWGGTRPDKGFDCSGLVFYAYNKILE
                     AKLPRTANEMYHYRRATIVANNDLRRGDLLFFHIHSREIADHMGVYLGDGQFIESPRT
                     GETIRISRLAEPFWQDHFLGARRILTEETIL"
     misc_feature    <247012..247431
                     /gene="yafL"
                     /locus_tag="b0227"
                     /gene_synonym="ECK0228; JW0217"
                     /note="Cell wall-associated hydrolases
                     (invasion-associated proteins) [Cell envelope biogenesis,
                     outer membrane]; Region: Spr; COG0791"
                     /db_xref="CDD:223862"
     misc_feature    247102..247434
                     /gene="yafL"
                     /locus_tag="b0227"
                     /gene_synonym="ECK0228; JW0217"
                     /note="NlpC/P60 family; Region: NLPC_P60; pfam00877"
                     /db_xref="CDD:189752"
     repeat_region   247458..247541
                     /note="REP18 (repetitive extragenic palindromic) element;
                     contains 2 REP sequences"
     gene            247637..248134
                     /gene="rayT"
                     /locus_tag="b0228"
                     /gene_synonym="ECK0229; JW0218; tnpAREP; yafM"
                     /db_xref="EcoGene:EG13150"
                     /db_xref="GeneID:944913"
     CDS             247637..248134
                     /gene="rayT"
                     /locus_tag="b0228"
                     /gene_synonym="ECK0229; JW0218; tnpAREP; yafM"
                     /codon_start=1
                     /transl_table=11
                     /product="RAYT REP element-mobilizing transposase;
                     TnpA(REP)"
                     /protein_id="NP_414763.1"
                     /db_xref="GI:16128214"
                     /db_xref="ASAP:ABE-0000779"
                     /db_xref="UniProtKB/Swiss-Prot:Q47152"
                     /db_xref="EcoGene:EG13150"
                     /db_xref="GeneID:944913"
                     /translation="MSEYRRYYIKGGTWFFTVNLRNRRSQLLTTQYQMLRHAIIKVKR
                     DRPFEINAWVVLPEHMHCIWTLPEGDDDFSSRWREIKKQFTHACGLKNIWQPRFWEHA
                     IRNTKDYRHHVDYIYINPVKHGWVKQVSDWPFSTFHRDVARGLYPIDWAGDVTDFSAG
                     ERIIS"
     misc_feature    247637..248041
                     /gene="rayT"
                     /locus_tag="b0228"
                     /gene_synonym="ECK0229; JW0218; tnpAREP; yafM"
                     /note="Transposase and inactivated derivatives [DNA
                     replication, recombination, and repair]; Region: COG1943"
                     /db_xref="CDD:224854"
     repeat_region   248147..248334
                     /note="REP19 (repetitive extragenic palindromic) element;
                     contains 4 REP sequences"
     gene            complement(248358..250070)
                     /gene="lfhA"
                     /locus_tag="b0229"
                     /gene_synonym="ECK0230; fhiA; JW5811"
                     /pseudo
                     /db_xref="EcoGene:EG13144"
                     /db_xref="GeneID:944908"
     CDS             complement(248358..250070)
                     /gene="lfhA"
                     /locus_tag="b0229"
                     /gene_synonym="ECK0230; fhiA; JW5811"
                     /GO_component="GO:0019861 - flagellum"
                     /GO_component="GO:0009274 - peptidoglycan-based cell wall"
                     /GO_component="GO:0019866 - organelle inner membrane"
                     /note="pseudogene, flagellar system protein, promoterless
                     fragment;
                     flagellar biosynthesis"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /db_xref="ASAP:ABE-0000782"
                     /db_xref="UniProtKB/Swiss-Prot:Q47153"
                     /db_xref="EcoGene:EG13144"
                     /db_xref="GeneID:944908"
     gene            250072..250827
                     /gene="lafU"
                     /locus_tag="b0230"
                     /gene_synonym="ECK0231; JW5812; mbhA"
                     /pseudo
                     /db_xref="EcoGene:EG13143"
                     /db_xref="GeneID:944921"
     CDS             250072..250827
                     /gene="lafU"
                     /locus_tag="b0230"
                     /gene_synonym="ECK0231; JW5812; mbhA"
                     /GO_process="GO:0042330 - taxis"
                     /note="pseudogene, lateral flagellar motor protein
                     fragment"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /db_xref="ASAP:ABE-0000785"
                     /db_xref="UniProtKB/Swiss-Prot:Q47154"
                     /db_xref="EcoGene:EG13143"
                     /db_xref="GeneID:944921"
     gene            250898..251953
                     /gene="dinB"
                     /locus_tag="b0231"
                     /gene_synonym="dinP; ECK0232; JW0221"
                     /db_xref="EcoGene:EG13141"
                     /db_xref="GeneID:944922"
     CDS             250898..251953
                     /gene="dinB"
                     /locus_tag="b0231"
                     /gene_synonym="dinP; ECK0232; JW0221"
                     /EC_number="2.7.7.7"
                     /GO_component="GO:0005737 - cytoplasm"
                     /GO_process="GO:0006261 - DNA-dependent DNA replication"
                     /GO_process="GO:0009432 - SOS response"
                     /note="DNA polymerase IV;
                     DNA polymerase IV, devoid of proofreading,
                     damage-inducible protein P"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase IV"
                     /protein_id="NP_414766.1"
                     /db_xref="GI:16128217"
                     /db_xref="ASAP:ABE-0000789"
                     /db_xref="UniProtKB/Swiss-Prot:Q47155"
                     /db_xref="EcoGene:EG13141"
                     /db_xref="GeneID:944922"
                     /translation="MRKIIHVDMDCFFAAVEMRDNPALRDIPIAIGGSRERRGVISTA
                     NYPARKFGVRSAMPTGMALKLCPHLTLLPGRFDAYKEASNHIREIFSRYTSRIEPLSL
                     DEAYLDVTDSVHCHGSATLIAQEIRQTIFNELQLTASAGVAPVKFLAKIASDMNKPNG
                     QFVITPAEVPAFLQTLPLAKIPGVGKVSAAKLEAMGLRTCGDVQKCDLVMLLKRFGKF
                     GRILWERSQGIDERDVNSERLRKSVGVERTMAEDIHHWSECEAIIERLYPELERRLAK
                     VKPDLLIARQGVKLKFDDFQQTTQEHVWPRLNKADLIATARKTWDERRGGRGVRLVGL
                     HVTLLDPQMERQLVLGL"
     misc_feature    250910..251914
                     /gene="dinB"
                     /locus_tag="b0231"
                     /gene_synonym="dinP; ECK0232; JW0221"
                     /note="DNA Polymerase IV/Kappa; Region: PolY_Pol_IV_kappa;
                     cd03586"
                     /db_xref="CDD:176459"
     misc_feature    order(250919..250924,250928..250936,251021..251026,
                     251033..251035,251042..251044,251204..251206,
                     251366..251368)
                     /gene="dinB"
                     /locus_tag="b0231"
                     /gene_synonym="dinP; ECK0232; JW0221"
                     /note="active site"
                     /db_xref="CDD:176459"
     misc_feature    250922..251950
                     /gene="dinB"
                     /locus_tag="b0231"
                     /gene_synonym="dinP; ECK0232; JW0221"
                     /note="DNA polymerase IV; Validated; Region: PRK02406"
                     /db_xref="CDD:235035"
     misc_feature    order(250994..250996,251069..251071,251198..251200,
                     251204..251209,251345..251347,251441..251461,
                     251546..251551,251618..251641,251714..251716,
                     251789..251800,251885..251890,251900..251902,
                     251909..251911)
                     /gene="dinB"
                     /locus_tag="b0231"
                     /gene_synonym="dinP; ECK0232; JW0221"
                     /note="DNA binding site [nucleotide binding]"
                     /db_xref="CDD:176459"
     gene            252005..252298
                     /gene="yafN"
                     /locus_tag="b0232"
                     /gene_synonym="ECK0233; JW0222"
                     /db_xref="EcoGene:EG13151"
                     /db_xref="GeneID:944920"
     CDS             252005..252298
                     /gene="yafN"
                     /locus_tag="b0232"
                     /gene_synonym="ECK0233; JW0222"
                     /codon_start=1
                     /transl_table=11
                     /product="antitoxin of the YafO-YafN toxin-antitoxin
                     system"
                     /protein_id="NP_414767.1"
                     /db_xref="GI:16128218"
                     /db_xref="ASAP:ABE-0000793"
                     /db_xref="UniProtKB/Swiss-Prot:Q47156"
                     /db_xref="EcoGene:EG13151"
                     /db_xref="GeneID:944920"
                     /translation="MHRILAEKSVNITELRKNPAKYFIDQPVAVLSNNRPAGYLLSAS
                     AFEALMDMLAEQEEKKPIKARFRPSAARLEEITRRAEQYLNDMTDDDFNDFKE"
     misc_feature    252005..252295
                     /gene="yafN"
                     /locus_tag="b0232"
                     /gene_synonym="ECK0233; JW0222"
                     /note="putative antitoxin of the YafO-YafN toxin-antitoxin
                     system; Provisional; Region: PRK09778"
                     /db_xref="CDD:170091"
     gene            252301..252699
                     /gene="yafO"
                     /locus_tag="b0233"
                     /gene_synonym="ECK0234; JW0223"
                     /db_xref="EcoGene:EG13152"
                     /db_xref="GeneID:944916"
     CDS             252301..252699
                     /gene="yafO"
                     /locus_tag="b0233"
                     /gene_synonym="ECK0234; JW0223"
                     /codon_start=1
                     /transl_table=11
                     /product="mRNA interferase toxin of the YafO-YafN
                     toxin-antitoxin system"
                     /protein_id="NP_414768.1"
                     /db_xref="GI:16128219"
                     /db_xref="ASAP:ABE-0000795"
                     /db_xref="UniProtKB/Swiss-Prot:Q47157"
                     /db_xref="EcoGene:EG13152"
                     /db_xref="GeneID:944916"
                     /translation="MRVFKTKLIRLQLTAEELDALTADFISYKRDGVLPDIFGRDALY
                     DDSFTWPLIKFERVAHIHLANENNPFPPQLRQFSRTNDEAHLVYCQGAFDEQAWLLIA
                     ILKPEPHKLARDNNQMHKIGKMAEAFRMRF"
     misc_feature    252301..252696
                     /gene="yafO"
                     /locus_tag="b0233"
                     /gene_synonym="ECK0234; JW0223"
                     /note="putative toxin YafO; Provisional; Region: PRK09885"
                     /db_xref="CDD:236631"
     gene            252709..253161
                     /gene="yafP"
                     /locus_tag="b0234"
                     /gene_synonym="ECK0235; JW0224"
                     /db_xref="EcoGene:EG13153"
                     /db_xref="GeneID:944912"
     CDS             252709..253161
                     /gene="yafP"
                     /locus_tag="b0234"
                     /gene_synonym="ECK0235; JW0224"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family putative N-acetyltransferase"
                     /protein_id="NP_414769.1"
                     /db_xref="GI:16128220"
                     /db_xref="ASAP:ABE-0000801"
                     /db_xref="UniProtKB/Swiss-Prot:Q47158"
                     /db_xref="EcoGene:EG13153"
                     /db_xref="GeneID:944912"
                     /translation="MNNIQIRNYQPGDFQQLCAIFIRAVTMTASQHYSPQQISAWAQI
                     DESRWKEKLAKSQVWVAIINAQPVGFISRIEHYIDMLFVDPEYTRRGVASALLKPLIK
                     SESELTVDASITAKPFFERYGFQTVKQQRVECRGAWFTNFYMRYKPQH"
     misc_feature    252745..253080
                     /gene="yafP"
                     /locus_tag="b0234"
                     /gene_synonym="ECK0235; JW0224"
                     /note="Acetyltransferase (GNAT) domain; Region:
                     Acetyltransf_10; pfam13673"
                     /db_xref="CDD:257979"
     misc_feature    252880..>253014
                     /gene="yafP"
                     /locus_tag="b0234"
                     /gene_synonym="ECK0235; JW0224"
                     /note="N-Acyltransferase superfamily: Various enzymes that
                     characteristically catalyze the transfer of an acyl group
                     to a substrate; Region: NAT_SF; cd04301"
                     /db_xref="CDD:173926"
     misc_feature    order(252949..252957,252985..252990)
                     /gene="yafP"
                     /locus_tag="b0234"
                     /gene_synonym="ECK0235; JW0224"
                     /note="Coenzyme A binding pocket [chemical binding]; other
                     site"
                     /db_xref="CDD:173926"
     gene            253479..253685
                     /gene="ykfJ"
                     /locus_tag="b0235"
                     /gene_synonym="ECK0236; JW0225"
                     /pseudo
                     /db_xref="EcoGene:EG14368"
                     /db_xref="GeneID:944924"
     CDS             253479..253685
                     /gene="ykfJ"
                     /locus_tag="b0235"
                     /gene_synonym="ECK0236; JW0225"
                     /note="pseudogene"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /db_xref="ASAP:ABE-0000805"
                     /db_xref="UniProtKB/Swiss-Prot:P75675"
                     /db_xref="EcoGene:EG14368"
                     /db_xref="GeneID:944924"
     gene            253702..254202
                     /gene="prfH"
                     /locus_tag="b0236"
                     /gene_synonym="ECK0237; JW0226"
                     /pseudo
                     /db_xref="EcoGene:EG11496"
                     /db_xref="GeneID:947374"
     CDS             253702..254202
                     /gene="prfH"
                     /locus_tag="b0236"
                     /gene_synonym="ECK0237; JW0226"
                     /GO_component="GO:0005737 - cytoplasm"
                     /GO_process="GO:0006412 - translation"
                     /note="pseudogene, RF-1 domain family;
                     probable peptide chain release factor"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /db_xref="ASAP:ABE-0000807"
                     /db_xref="UniProtKB/Swiss-Prot:P28369"
                     /db_xref="EcoGene:EG11496"
                     /db_xref="GeneID:947374"
     repeat_region   254217..254244
                     /note="REP20 (repetitive extragenic palindromic) element;
                     contains 1 REP sequences"
     gene            complement(254259..255716)
                     /gene="pepD"
                     /locus_tag="b0237"
                     /gene_synonym="ECK0238; JW0227; pepH"
                     /db_xref="EcoGene:EG10695"
                     /db_xref="GeneID:945013"
     CDS             complement(254259..255716)
                     /gene="pepD"
                     /locus_tag="b0237"
                     /gene_synonym="ECK0238; JW0227; pepH"
                     /EC_number="3.4.13.18"
                     /function="enzyme; Degradation of proteins, peptides,
                     glyco"
                     /GO_component="GO:0005737 - cytoplasm"
                     /codon_start=1
                     /transl_table=11
                     /product="aminoacyl-histidine dipeptidase (peptidase D)"
                     /protein_id="NP_414772.1"
                     /db_xref="GI:16128223"
                     /db_xref="ASAP:ABE-0000809"
                     /db_xref="UniProtKB/Swiss-Prot:P15288"
                     /db_xref="EcoGene:EG10695"
                     /db_xref="GeneID:945013"
                     /translation="MSELSQLSPQPLWDIFAKICSIPHPSYHEEQLAEYIVGWAKEKG
                     FHVERDQVGNILIRKPATAGMENRKPVVLQAHLDMVPQKNNDTVHDFTKDPIQPYIDG
                     EWVKARGTTLGADNGIGMASALAVLADENVVHGPLEVLLTMTEEAGMDGAFGLQGNWL
                     QADILINTDSEEEGEIYMGCAGGIDFTSNLHLDREAVPAGFETFKLTLKGLKGGHSGG
                     EIHVGLGNANKLLVRFLAGHAEELDLRLIDFNGGTLRNAIPREAFATIAVAADKVDVL
                     KSLVNTYQEILKNELAEKEKNLALLLDSVANDKAALIAKSRDTFIRLLNATPNGVIRN
                     SDVAKGVVETSLNVGVVTMTDNNVEIHCLIRSLIDSGKDYVVSMLDSLGKLAGAKTEA
                     KGAYPGWQPDANSPVMHLVRETYQRLFNKTPNIQIIHAGLECGLFKKPYPEMDMVSIG
                     PTITGPHSPDEQVHIESVGHYWTLLTELLKEIPAK"
     misc_feature    complement(254271..255698)
                     /gene="pepD"
                     /locus_tag="b0237"
                     /gene_synonym="ECK0238; JW0227; pepH"
                     /note="Xaa-His dipeptidase; Region: aa-his-dipept;
                     TIGR01893"
                     /db_xref="CDD:233622"
     misc_feature    complement(254271..255692)
                     /gene="pepD"
                     /locus_tag="b0237"
                     /gene_synonym="ECK0238; JW0227; pepH"
                     /note="M20 Peptidase D has specificity for
                     beta-alanyl-L-histidine dipeptide; Region: M20_pepD;
                     cd03890"
                     /db_xref="CDD:193510"
     misc_feature    complement(order(254346..254348,255210..255212,
                     255279..255284,255372..255374,255489..255491))
                     /gene="pepD"
                     /locus_tag="b0237"
                     /gene_synonym="ECK0238; JW0227; pepH"
                     /note="metal binding site [ion binding]; metal-binding
                     site"
                     /db_xref="CDD:193510"
     misc_feature    complement(order(254571..254576,254583..254588,
                     254595..254597,254706..254711,254718..254720,
                     254739..254744,254748..254753,254847..254849,
                     254859..254861,255018..255020,255048..255050))
                     /gene="pepD"
                     /locus_tag="b0237"
                     /gene_synonym="ECK0238; JW0227; pepH"
                     /note="dimer interface [polypeptide binding]; other site"
                     /db_xref="CDD:193510"
     gene            255977..256435
                     /gene="gpt"
                     /locus_tag="b0238"
                     /gene_synonym="ECK0239; gpp; gxu; JW0228"
                     /db_xref="EcoGene:EG10414"
                     /db_xref="GeneID:944817"
     CDS             255977..256435
                     /gene="gpt"
                     /locus_tag="b0238"
                     /gene_synonym="ECK0239; gpp; gxu; JW0228"
                     /EC_number="2.4.2.22"
                     /function="enzyme; Salvage of nucleosides and nucleotides"
                     /GO_component="GO:0005737 - cytoplasm"
                     /GO_process="GO:0015949 - nucleobase, nucleoside and
                     nucleotide interconversion"
                     /codon_start=1
                     /transl_table=11
                     /product="xanthine phosphoribosyltransferase;
                     xanthine-guanine phosphoribosyltransferase"
                     /protein_id="NP_414773.1"
                     /db_xref="GI:16128224"
                     /db_xref="ASAP:ABE-0000814"
                     /db_xref="UniProtKB/Swiss-Prot:P0A9M5"
                     /db_xref="EcoGene:EG10414"
                     /db_xref="GeneID:944817"
                     /translation="MSEKYIVTWDMLQIHARKLASRLMPSEQWKGIIAVSRGGLVPGA
                     LLARELGIRHVDTVCISSYDHDNQRELKVLKRAEGDGEGFIVIDDLVDTGGTAVAIRE
                     MYPKAHFVTIFAKPAGRPLVDDYVVDIPQDTWIEQPWDMGVVFVPPISGR"
     misc_feature    256070..256363
                     /gene="gpt"
                     /locus_tag="b0238"
                     /gene_synonym="ECK0239; gpp; gxu; JW0228"
                     /note="Phosphoribosyl transferase (PRT)-type I domain;
                     Region: PRTases_typeI; cd06223"
                     /db_xref="CDD:206754"
     misc_feature    order(256082..256084,256088..256090,256238..256246,
                     256250..256264,256319..256321)
                     /gene="gpt"
                     /locus_tag="b0238"
                     /gene_synonym="ECK0239; gpp; gxu; JW0228"
                     /note="active site"
                     /db_xref="CDD:206754"
     gene            256527..257771
                     /gene="frsA"
                     /locus_tag="b0239"
                     /gene_synonym="ECK0240; JW0229; yafA"
                     /db_xref="EcoGene:EG11091"
                     /db_xref="GeneID:946039"
     CDS             256527..257771
                     /gene="frsA"
                     /locus_tag="b0239"
                     /gene_synonym="ECK0240; JW0229; yafA"
                     /codon_start=1
                     /transl_table=11
                     /product="fermentation-respiration switch protein; PTS
                     Enzyme IIA(Glc)-binding protein; pNP-butyrate esterase
                     activity"
                     /protein_id="NP_414774.1"
                     /db_xref="GI:16128225"
                     /db_xref="ASAP:ABE-0000817"
                     /db_xref="UniProtKB/Swiss-Prot:P04335"
                     /db_xref="EcoGene:EG11091"
                     /db_xref="GeneID:946039"
                     /translation="MTQANLSETLFKPRFKHPETSTLVRRFNHGAQPPVQSALDGKTI
                     PHWYRMINRLMWIWRGIDPREILDVQARIVMSDAERTDDDLYDTVIGYRGGNWIYEWA
                     TQAMVWQQKACAEDDPQLSGRHWLHAATLYNIAAYPHLKGDDLAEQAQALSNRAYEEA
                     AQRLPGTMRQMEFTVPGGAPITGFLHMPKGDGPFPTVLMCGGLDAMQTDYYSLYERYF
                     APRGIAMLTIDMPSVGFSSKWKLTQDSSLLHQHVLKALPNVPWVDHTRVAAFGFRFGA
                     NVAVRLAYLESPRLKAVACLGPVVHTLLSDFKCQQQVPEMYLDVLASRLGMHDASDEA
                     LRVELNRYSLKVQGLLGRRCPTPMLSGYWKNDPFSPEEDSRLITSSSADGKLLEIPFN
                     PVYRNFDKGLQEITDWIEKRLC"
     misc_feature    256527..257768
                     /gene="frsA"
                     /locus_tag="b0239"
                     /gene_synonym="ECK0240; JW0229; yafA"
                     /note="Alpha/beta hydrolase of unknown function (DUF1100);
                     Region: DUF1100; pfam06500"
                     /db_xref="CDD:115172"
     misc_feature    256527..257768
                     /gene="frsA"
                     /locus_tag="b0239"
                     /gene_synonym="ECK0240; JW0229; yafA"
                     /note="fermentation/respiration switch protein; Reviewed;
                     Region: frsA; PRK05077"
                     /db_xref="CDD:235337"
     gene            join(257829..257899,258676..259006)
                     /gene="crl"
                     /locus_tag="b0240"
                     /gene_synonym="ECK0241; JW0230"
                     /pseudo
                     /db_xref="EcoGene:EG11092"
                     /db_xref="GeneID:945077"
     CDS             join(257829..257899,258676..259006)
                     /gene="crl"
                     /locus_tag="b0240"
                     /gene_synonym="ECK0241; JW0230"
                     /GO_component="GO:0009289 - pilus"
                     /GO_component="GO:0005737 - cytoplasm"
                     /GO_function="GO:0016563 - transcription activator
                     activity"
                     /GO_process="GO:0006350 - transcription"
                     /note="pseudogene, sigma factor-binding protein, RNA
                     polymerase holoenzyme formation stimulator;regulator;
                     Surface structures;
                     transcriptional regulator of cryptic csgA gene for curli
                     surface fibers"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /db_xref="ASAP:ABE-0000821"
                     /db_xref="UniProtKB/Swiss-Prot:P24251"
                     /db_xref="EcoGene:EG11092"
                     /db_xref="GeneID:945077"
     mobile_element  complement(257908..258675)
                     /mobile_element_type="insertion sequence:IS1I"
     repeat_region   259016..259036
                     /note="REP21 (repetitive extragenic palindromic) element;
                     contains 1 REP sequences"
     gene            complement(259045..260100)
                     /gene="phoE"
                     /locus_tag="b0241"
                     /gene_synonym="ECK0242; JW0231; ompE"
                     /db_xref="EcoGene:EG10729"
                     /db_xref="GeneID:944926"
     CDS             complement(259045..260100)
                     /gene="phoE"
                     /locus_tag="b0241"
                     /gene_synonym="ECK0242; JW0231; ompE"
                     /function="membrane; Outer membrane constituents"
                     /GO_component="GO:0009274 - peptidoglycan-based cell wall"
                     /GO_component="GO:0009279 - cell outer membrane"
                     /note="outer membrane pore protein E (E,Ic,NmpAB)"
                     /codon_start=1
                     /transl_table=11
                     /product="outer membrane phosphoporin protein E"
                     /protein_id="NP_414776.1"
                     /db_xref="GI:16128227"
                     /db_xref="ASAP:ABE-0000823"
                     /db_xref="UniProtKB/Swiss-Prot:P02932"
                     /db_xref="EcoGene:EG10729"
                     /db_xref="GeneID:944926"
                     /translation="MKKSTLALVVMGIVASASVQAAEIYNKDGNKLDVYGKVKAMHYM
                     SDNASKDGDQSYIRFGFKGETQINDQLTGYGRWEAEFAGNKAESDTAQQKTRLAFAGL
                     KYKDLGSFDYGRNLGALYDVEAWTDMFPEFGGDSSAQTDNFMTKRASGLATYRNTDFF
                     GVIDGLNLTLQYQGKNENRDVKKQNGDGFGTSLTYDFGGSDFAISGAYTNSDRTNEQN
                     LQSRGTGKRAEAWATGLKYDANNIYLATFYSETRKMTPITGGFANKTQNFEAVAQYQF
                     DFGLRPSLGYVLSKGKDIEGIGDEDLVNYIDVGATYYFNKNMSAFVDYKINQLDSDNK
                     LNINNDDIVAVGMTYQF"
     misc_feature    complement(259048..260013)
                     /gene="phoE"
                     /locus_tag="b0241"
                     /gene_synonym="ECK0242; JW0231; ompE"
                     /note="Porins form aqueous channels for the diffusion of
                     small hydrophillic molecules across the outer membrane.
                     Individual 16-strand anti-parallel beta-barrels form a
                     central pore, and trimerizes thru mainly hydrophobic
                     interactions at the interface. Trimers...; Region:
                     gram_neg_porins; cd00342"
                     /db_xref="CDD:238208"
     misc_feature    complement(order(259048..259050,259054..259056,
                     259060..259062,259147..259149,259156..259161,
                     259651..259656,259660..259662,259759..259767,
                     259795..259809,259813..259818,259849..259860,
                     259864..259866,259870..259878,259882..259884,
                     259900..259914,259975..259983,259987..259989,
                     260005..260007,260011..260013))
                     /gene="phoE"
                     /locus_tag="b0241"
                     /gene_synonym="ECK0242; JW0231; ompE"
                     /note="trimer interface [polypeptide binding]; other site"
                     /db_xref="CDD:238208"
     misc_feature    complement(order(259660..259662,259720..259722,
                     259813..259815,259927..259929,259990..259992))
                     /gene="phoE"
                     /locus_tag="b0241"
                     /gene_synonym="ECK0242; JW0231; ompE"
                     /note="eyelet of channel; other site"
                     /db_xref="CDD:238208"
     gene            260388..261491
                     /gene="proB"
                     /locus_tag="b0242"
                     /gene_synonym="ECK0243; JW0232; pro"
                     /db_xref="EcoGene:EG10768"
                     /db_xref="GeneID:946425"
     CDS             260388..261491
                     /gene="proB"
                     /locus_tag="b0242"
                     /gene_synonym="ECK0243; JW0232; pro"
                     /EC_number="2.7.2.11"
                     /function="enzyme; Amino acid biosynthesis: Proline"
                     /experiment="N-terminus verified by Edman degradation:
                     PMID 6089111"
                     /GO_component="GO:0005737 - cytoplasm"
                     /GO_process="GO:0006561 - proline biosynthetic process"
                     /codon_start=1
                     /transl_table=11
                     /product="gamma-glutamate kinase"
                     /protein_id="NP_414777.1"
                     /db_xref="GI:16128228"
                     /db_xref="ASAP:ABE-0000830"
                     /db_xref="UniProtKB/Swiss-Prot:P0A7B5"
                     /db_xref="EcoGene:EG10768"
                     /db_xref="GeneID:946425"
                     /translation="MSDSQTLVVKLGTSVLTGGSRRLNRAHIVELVRQCAQLHAAGHR
                     IVIVTSGAIAAGREHLGYPELPATIASKQLLAAVGQSRLIQLWEQLFSIYGIHVGQML
                     LTRADMEDRERFLNARDTLRALLDNNIVPVINENDAVATAEIKVGDNDNLSALAAILA
                     GADKLLLLTDQKGLYTADPRSNPQAELIKDVYGIDDALRAIAGDSVSGLGTGGMSTKL
                     QAADVACRAGIDTIIAAGSKPGVIGDVMEGISVGTLFHAQATPLENRKRWIFGAPPAG
                     EITVDEGATAAILERGSSLLPKGIKSVTGNFSRGEVIRICNLEGRDIAHGVSRYNSDA
                     LRRIAGHHSQEIDAILGYEYGPVAVHRDDMITR"
     misc_feature    260388..261482
                     /gene="proB"
                     /locus_tag="b0242"
                     /gene_synonym="ECK0243; JW0232; pro"
                     /note="gamma-glutamyl kinase; Provisional; Region:
                     PRK05429"
                     /db_xref="CDD:235460"
     misc_feature    260403..261155
                     /gene="proB"
                     /locus_tag="b0242"
                     /gene_synonym="ECK0243; JW0232; pro"
                     /note="AAK_G5K_ProB: Glutamate-5-kinase (G5K) catalyzes
                     glutamate-dependent ATP cleavage; G5K transfers the
                     terminal phosphoryl group of ATP to the gamma-carboxyl
                     group of glutamate, in the first and controlling step of
                     proline (and, in mammals, ornithine)...; Region:
                     AAK_G5K_ProB; cd04242"
                     /db_xref="CDD:239775"
     misc_feature    order(260427..260429,260892..260900,260907..260912,
                     261018..261020,261024..261026,261036..261038)
                     /gene="proB"
                     /locus_tag="b0242"
                     /gene_synonym="ECK0243; JW0232; pro"
                     /note="nucleotide binding site [chemical binding]; other
                     site"
                     /db_xref="CDD:239775"
     misc_feature    order(260502..260507,260514..260516,260604..260606,
                     260616..260618,260685..260687,260691..260693,
                     260733..260738,260754..260756,260763..260765,
                     260793..260795,260799..260804)
                     /gene="proB"
                     /locus_tag="b0242"
                     /gene_synonym="ECK0243; JW0232; pro"
                     /note="homotetrameric interface [polypeptide binding];
                     other site"
                     /db_xref="CDD:239775"
     misc_feature    260538..260561
                     /gene="proB"
                     /locus_tag="b0242"
                     /gene_synonym="ECK0243; JW0232; pro"
                     /note="putative phosphate binding site [ion binding];
                     other site"
                     /db_xref="CDD:239775"
     misc_feature    order(260541..260543,260796..260798,260829..260831)
                     /gene="proB"
                     /locus_tag="b0242"
                     /gene_synonym="ECK0243; JW0232; pro"
                     /note="putative allosteric binding site; other site"
                     /db_xref="CDD:239775"
     misc_feature    261213..261437
                     /gene="proB"
                     /locus_tag="b0242"
                     /gene_synonym="ECK0243; JW0232; pro"
                     /note="PUA domain; Region: PUA; pfam01472"
                     /db_xref="CDD:250644"
     gene            261503..262756
                     /gene="proA"
                     /locus_tag="b0243"
                     /gene_synonym="ECK0244; JW0233; pro"
                     /db_xref="EcoGene:EG10767"
                     /db_xref="GeneID:946680"
     CDS             261503..262756
                     /gene="proA"
                     /locus_tag="b0243"
                     /gene_synonym="ECK0244; JW0233; pro"
                     /EC_number="1.2.1.41"
                     /function="enzyme; Amino acid biosynthesis: Proline"
                     /experiment="N-terminus verified by Edman degradation:
                     PMID 6089111"
                     /GO_component="GO:0005737 - cytoplasm"
                     /GO_process="GO:0006561 - proline biosynthetic process"
                     /codon_start=1
                     /transl_table=11
                     /product="gamma-glutamylphosphate reductase"
                     /protein_id="NP_414778.1"
                     /db_xref="GI:16128229"
                     /db_xref="ASAP:ABE-0000832"
                     /db_xref="UniProtKB/Swiss-Prot:P07004"
                     /db_xref="EcoGene:EG10767"
                     /db_xref="GeneID:946680"
                     /translation="MLEQMGIAAKQASYKLAQLSSREKNRVLEKIADELEAQSEIILN
                     ANAQDVADARANGLSEAMLDRLALTPARLKGIADDVRQVCNLADPVGQVIDGGVLDSG
                     LRLERRRVPLGVIGVIYEARPNVTVDVASLCLKTGNAVILRGGKETCRTNAATVAVIQ
                     DALKSCGLPAGAVQAIDNPDRALVSEMLRMDKYIDMLIPRGGAGLHKLCREQSTIPVI
                     TGGIGVCHIYVDESVEIAEALKVIVNAKTQRPSTCNTVETLLVNKNIADSFLPALSKQ
                     MAESGVTLHADAAALAQLQAGPAKVVAVKAEEYDDEFLSLDLNVKIVSDLDDAIAHIR
                     EHGTQHSDAILTRDMRNAQRFVNEVDSSAVYVNASTRFTDGGQFGLGAEVAVSTQKLH
                     ARGPMGLEALTTYKWIGIGDYTIRA"
     misc_feature    261509..262738
                     /gene="proA"
                     /locus_tag="b0243"
                     /gene_synonym="ECK0244; JW0233; pro"
                     /note="Gamma-glutamyl phosphate reductase (GPR), aldehyde
                     dehydrogenase families 18 and 19; Region:
                     ALDH_F18-19_ProA-GPR; cd07079"
                     /db_xref="CDD:143398"
     misc_feature    262259..262261
                     /gene="proA"
                     /locus_tag="b0243"
                     /gene_synonym="ECK0244; JW0233; pro"
                     /note="putative catalytic cysteine [active]"
                     /db_xref="CDD:143398"
     gene            262871..262946
                     /gene="thrW"
                     /locus_tag="b0244"
                     /gene_synonym="ECK0245; JWR0008"
                     /db_xref="EcoGene:EG30104"
                     /db_xref="GeneID:947202"
     tRNA            262871..262946
                     /gene="thrW"
                     /locus_tag="b0244"
                     /gene_synonym="ECK0245; JWR0008"
                     /product="tRNA-Thr"
                     /note="anticodon: CGU"
                     /db_xref="ASAP:ABE-0000834"
                     /db_xref="EcoGene:EG30104"
                     /db_xref="GeneID:947202"
     misc_feature    262958..297265
                     /note="cryptic prophage CP4-6"
     gene            complement(263150..263212)
                     /gene="ykfN"
                     /locus_tag="b4626"
                     /gene_synonym="ECK4458"
                     /pseudo
                     /db_xref="EcoGene:EG14454"
                     /db_xref="GeneID:5625552"
     CDS             complement(263150..263212)
                     /gene="ykfN"
                     /locus_tag="b4626"
                     /gene_synonym="ECK4458"
                     /note="pseudogene, YdiA family"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /db_xref="EcoGene:EG14454"
                     /db_xref="GeneID:5625552"
     gene            complement(263328..263669)
                     /gene="ykfI"
                     /locus_tag="b0245"
                     /gene_synonym="ECK0246; JW0234"
                     /db_xref="EcoGene:EG14333"
                     /db_xref="GeneID:946726"
     CDS             complement(263328..263669)
                     /gene="ykfI"
                     /locus_tag="b0245"
                     /gene_synonym="ECK0246; JW0234"
                     /function="Phage or Prophage Related"
                     /codon_start=1
                     /transl_table=11
                     /product="CP4-6 prophage; toxin of the YkfI-YafW
                     toxin-antitoxin system"
                     /protein_id="NP_414779.1"
                     /db_xref="GI:16128230"
                     /db_xref="ASAP:ABE-0000836"
                     /db_xref="UniProtKB/Swiss-Prot:P77692"
                     /db_xref="EcoGene:EG14333"
                     /db_xref="GeneID:946726"
                     /translation="MKTLPAITQRAVKPCLSPVAVWQMLLTRLLEQHYGLTINDTPFC
                     NEAVIKEHIDAGITLADAVNFLVEKYELVRIDRKGFSWQEQSPYLRAADILRARQATG
                     LLRQSRNNVVR"
     misc_feature    complement(263355..263669)
                     /gene="ykfI"
                     /locus_tag="b0245"
                     /gene_synonym="ECK0246; JW0234"
                     /note="Protein of unknown function (DUF1219); Region:
                     DUF1219; pfam06755"
                     /db_xref="CDD:253895"
     gene            complement(263690..264007)
                     /gene="yafW"
                     /locus_tag="b0246"
                     /gene_synonym="ECK0247; JW0235"
                     /db_xref="EcoGene:EG13335"
                     /db_xref="GeneID:944929"
     CDS             complement(263690..264007)
                     /gene="yafW"
                     /locus_tag="b0246"
                     /gene_synonym="ECK0247; JW0235"
                     /function="Phage or Prophage Related"
                     /codon_start=1
                     /transl_table=11
                     /product="CP4-6 prophage; antitoxin of the YkfI-YafW
                     toxin-antitoxin system"
                     /protein_id="NP_414780.1"
                     /db_xref="GI:16128231"
                     /db_xref="ASAP:ABE-0000838"
                     /db_xref="UniProtKB/Swiss-Prot:Q47684"
                     /db_xref="EcoGene:EG13335"
                     /db_xref="GeneID:944929"
                     /translation="MSNPTRGLQREITLRLGARLVQEGNRLHYLADRASITGKFSDIE
                     CRKLDETFPHFILQMESMLTTGELSPHHAHCVTLYHNDLTCEADTLGSCGYVYIAIYP
                     TQR"
     misc_feature    complement(263693..264004)
                     /gene="yafW"
                     /locus_tag="b0246"
                     /gene_synonym="ECK0247; JW0235"
                     /note="YagB/YeeU/YfjZ family; Region: YagB_YeeU_YfjZ;
                     pfam06154"
                     /db_xref="CDD:114849"
     gene            complement(264026..264247)
                     /gene="ykfH"
                     /locus_tag="b4504"
                     /gene_synonym="ECK0248; JW5956"
                     /db_xref="EcoGene:EG14332"
                     /db_xref="GeneID:1450236"
     CDS             complement(264026..264247)
                     /gene="ykfH"
                     /locus_tag="b4504"
                     /gene_synonym="ECK0248; JW5956"
                     /GO_component="GO:0005737 - cytoplasm"
                     /codon_start=1
                     /transl_table=11
                     /product="uncharacterized protein"
                     /protein_id="YP_588435.1"
                     /db_xref="GI:94541094"
                     /db_xref="ASAP:ABE-0285025"
                     /db_xref="UniProtKB/Swiss-Prot:Q9XB42"
                     /db_xref="EcoGene:EG14332"
                     /db_xref="GeneID:1450236"
                     /translation="MKIISKRRAMTIYRQHPESRIFRYCTGKYQWHGSVCHYTGRDVP
                     DIAGVLAVYAERRQDRNGPYTCLMSITLN"
     misc_feature    complement(264050..264247)
                     /gene="ykfH"
                     /locus_tag="b4504"
                     /gene_synonym="ECK0248; JW5956"
                     /note="Protein of unknown function (DUF987); Region:
                     DUF987; pfam06174"
                     /db_xref="CDD:114867"
     gene            complement(264256..264732)
                     /gene="ykfG"
                     /locus_tag="b0247"
                     /gene_synonym="ECK0249; JW0236"
                     /db_xref="EcoGene:EG14331"
                     /db_xref="GeneID:944930"
     CDS             complement(264256..264732)
                     /gene="ykfG"
                     /locus_tag="b0247"
                     /gene_synonym="ECK0249; JW0236"
                     /function="Phage or Prophage Related"
                     /note="putative DNA repair protein"
                     /codon_start=1
                     /transl_table=11
                     /product="CP4-6 prophage; RadC-like JAB domain protein"
                     /protein_id="NP_414781.1"
                     /db_xref="GI:16128232"
                     /db_xref="ASAP:ABE-0000841"
                     /db_xref="UniProtKB/Swiss-Prot:Q47685"
                     /db_xref="EcoGene:EG14331"
                     /db_xref="GeneID:944930"
                     /translation="MKQLSFLPGEMTPQDRRLIQRALRALDRHLHEPGVAFTSTHAVR
                     EWLRLHMAALEREEFRVLYLDNQNQLIAHETLFTGTINRTEVHPREVVKRALHFNAAA
                     VILAHNHPSGETTPSQADKTLTQRLVQVLQLVDIRVPDHLIVGGRQIYSFAEHGLL"
     misc_feature    complement(264259..>264732)
                     /gene="ykfG"
                     /locus_tag="b0247"
                     /gene_synonym="ECK0249; JW0236"
                     /note="DNA repair proteins [DNA replication,
                     recombination, and repair]; Region: RadC; COG2003"
                     /db_xref="CDD:224914"
     misc_feature    complement(264274..264612)
                     /gene="ykfG"
                     /locus_tag="b0247"
                     /gene_synonym="ECK0249; JW0236"
                     /note="Mov34/MPN/PAD-1 family; Region: MPN_DUF2466;
                     cd08071"
                     /db_xref="CDD:163702"
     misc_feature    complement(order(264373..264375,264382..264384,
                     264406..264408,264412..264414,264562..264564))
                     /gene="ykfG"
                     /locus_tag="b0247"
                     /gene_synonym="ECK0249; JW0236"
                     /note="MPN+ (JAMM) motif; other site"
                     /db_xref="CDD:163702"
     misc_feature    complement(order(264373..264375,264406..264408,
                     264412..264414))
                     /gene="ykfG"
                     /locus_tag="b0247"
                     /gene_synonym="ECK0249; JW0236"
                     /note="Zinc-binding site [ion binding]; other site"
                     /db_xref="CDD:163702"
     gene            complement(264748..265206)
                     /gene="yafX"
                     /locus_tag="b0248"
                     /gene_synonym="ECK0250; JW5022"
                     /db_xref="EcoGene:EG13336"
                     /db_xref="GeneID:944931"
     CDS             complement(264748..265206)
                     /gene="yafX"
                     /locus_tag="b0248"
                     /gene_synonym="ECK0250; JW5022"
                     /function="Phage or Prophage Related"
                     /codon_start=1
                     /transl_table=11
                     /product="CP4-6 prophage; uncharacterized protein"
                     /protein_id="NP_414782.1"
                     /db_xref="GI:16128233"
                     /db_xref="ASAP:ABE-0000843"
                     /db_xref="UniProtKB/Swiss-Prot:P75676"
                     /db_xref="EcoGene:EG13336"
                     /db_xref="GeneID:944931"
                     /translation="MTTQTQHDLAPANQPEFELTVTPVPDEQRIDFWPQYFGAIPQWL
                     LLEPHIFAWMDRFCEGYSGGIWSFYTLSNGGAFMSPEPDNDETWRLFNCLNGNDAQMS
                     AEAAGIAVCLIAYSHHACRTECDAMTAHYYRLREYAMQHPEAHAILRIID"
     misc_feature    complement(264751..265038)
                     /gene="yafX"
                     /locus_tag="b0248"
                     /gene_synonym="ECK0250; JW5022"
                     /note="Antirestriction protein; Region: Antirestrict;
                     pfam03230"
                     /db_xref="CDD:251814"
     gene            complement(265304..265543)
                     /gene="ykfF"
                     /locus_tag="b0249"
                     /gene_synonym="ECK0251; JW5023"
                     /db_xref="EcoGene:EG14283"
                     /db_xref="GeneID:948839"
     CDS             complement(265304..265543)
                     /gene="ykfF"
                     /locus_tag="b0249"
                     /gene_synonym="ECK0251; JW5023"
                     /function="Phage or Prophage Related"
                     /codon_start=1
                     /transl_table=11
                     /product="CP4-6 prophage; uncharacterized protein"
                     /protein_id="NP_414783.1"
                     /db_xref="GI:16128234"
                     /db_xref="ASAP:ABE-0000846"
                     /db_xref="UniProtKB/Swiss-Prot:P75677"
                     /db_xref="EcoGene:EG14283"
                     /db_xref="GeneID:948839"
                     /translation="MTQSVLLPPGPFTRRQAQAVTTTYSNITLEDDQGSHFRLVVRDT
                     EGRMVWRAWNFEPDAGEGLNRYIRTSGIRTDTATR"
     misc_feature    complement(265322..265534)
                     /gene="ykfF"
                     /locus_tag="b0249"
                     /gene_synonym="ECK0251; JW5023"
                     /note="Bacterial protein of unknown function (DUF905);
                     Region: DUF905; pfam06006"
                     /db_xref="CDD:114712"
     gene            complement(265620..266087)
                     /gene="ykfB"
                     /locus_tag="b0250"
                     /gene_synonym="ECK0252; JW0239"
                     /db_xref="EcoGene:EG13548"
                     /db_xref="GeneID:946846"
     CDS             complement(265620..266087)
                     /gene="ykfB"
                     /locus_tag="b0250"
                     /gene_synonym="ECK0252; JW0239"
                     /function="Phage or Prophage Related"
                     /codon_start=1
                     /transl_table=11
                     /product="CP4-6 prophage; uncharacterized protein"
                     /protein_id="NP_414784.1"
                     /db_xref="GI:16128235"
                     /db_xref="ASAP:ABE-0000851"
                     /db_xref="UniProtKB/Swiss-Prot:P77162"
                     /db_xref="EcoGene:EG13548"
                     /db_xref="GeneID:946846"
                     /translation="MTILSLSRFMLAGVLLASFNASAIPGFWQQGYGQGNTEYSVTEA
                     SGKTFTINCTGNPDQNGFYQHSVFLTLADDKMVSSHDDDTTITVVMDHQQYIIPSSLG
                     WRNGDNAWFDFISNISEAGQFDVYVNDHKAGTFTADRKNAEKVLSTLGDCSND"
     gene            complement(266110..266553)
                     /gene="yafY"
                     /locus_tag="b0251"
                     /gene_synonym="ECK0253; JW0240"
                     /db_xref="EcoGene:EG13337"
                     /db_xref="GeneID:944934"
     CDS             complement(266110..266553)
                     /gene="yafY"
                     /locus_tag="b0251"
                     /gene_synonym="ECK0253; JW0240"
                     /function="Phage or Prophage Related"
                     /note="hypothetical transcriptional regulator"
                     /codon_start=1
                     /transl_table=11
                     /product="lipoprotein, inner membrane; degP regulator;
                     CP4-6 prophage"
                     /protein_id="NP_414785.4"
                     /db_xref="GI:145698221"
                     /db_xref="ASAP:ABE-0000853"
                     /db_xref="UniProtKB/Swiss-Prot:P77365"
                     /db_xref="EcoGene:EG13337"
                     /db_xref="GeneID:944934"
                     /translation="MKRKTLPLLALVATTLFLIACDDRSDDLKAISKFKDLTPPRFSD
                     VVSHQDDVSEEWSQVDYLSGPTLQVLRTRQSPDGCEDGSYYYLVDMQEKTVQPLMNAL
                     CIADNIKLEYQEVTDPYTKEKYFEYAHDGKLMGQLLIPSNPDNQE"
     misc_feature    complement(266116..>266553)
                     /gene="yafY"
                     /locus_tag="b0251"
                     /gene_synonym="ECK0253; JW0240"
                     /note="Predicted transcriptional regulator
                     [Transcription]; Region: COG2378"
                     /db_xref="CDD:225253"
     gene            complement(266553..266774)
                     /gene="ykfL"
                     /locus_tag="b4627"
                     /gene_synonym="ECK4445"
                     /pseudo
                     /db_xref="EcoGene:EG14378"
                     /db_xref="GeneID:5625553"
     CDS             complement(266553..266774)
                     /gene="ykfL"
                     /locus_tag="b4627"
                     /gene_synonym="ECK4445"
                     /note="pseudogene, CP4-6 putative prophage remnant;Phage
                     or Prophage Related"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /db_xref="EcoGene:EG14378"
                     /db_xref="GeneID:5625553"
     gene            complement(266776..266967)
                     /gene="ykfK"
                     /locus_tag="b4628"
                     /gene_synonym="ECK4444; yafY"
                     /pseudo
                     /db_xref="EcoGene:EG14377"
                     /db_xref="GeneID:5625554"
     CDS             complement(266776..266967)
                     /gene="ykfK"
                     /locus_tag="b4628"
                     /gene_synonym="ECK4444; yafY"
                     /note="CP4-6 prophage; putative DNA-binding
                     transcriptional regulator;Phage or Prophage Related"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /db_xref="EcoGene:EG14377"
                     /db_xref="GeneID:5625554"
     gene            complement(267184..268005)
                     /gene="yafZ"
                     /locus_tag="b0252"
                     /gene_synonym="ECK0254; JW0242"
                     /db_xref="EcoGene:EG13338"
                     /db_xref="GeneID:945373"
     CDS             complement(267184..268005)
                     /gene="yafZ"
                     /locus_tag="b0252"
                     /gene_synonym="ECK0254; JW0242"
                     /function="Phage or Prophage Related"
                     /codon_start=1
                     /transl_table=11
                     /product="CP4-6 prophage; conserved protein"
                     /protein_id="NP_414786.4"
                     /db_xref="GI:90111102"
                     /db_xref="ASAP:ABE-0000856"
                     /db_xref="UniProtKB/Swiss-Prot:P77206"
                     /db_xref="EcoGene:EG13338"
                     /db_xref="GeneID:945373"
                     /translation="MTRLASRFGAANLIRRDRPLTREELFRVVPSVFSEDKHESRSER
                     YTYIPTISLLDSLQREGFQPFFACQTRVRDPGRREHTKHMLRLRREGQITGKQVPEII
                     LLNSHDGTSSYQMLPGLFRAVCQNGLVCGESFGEVRVPHKGDVVSQVIEGAYEVLGIF
                     DRVEEKRDAMQSLLLPPPAQQALAKAALTYRFGEDHQPVTESQILSPRRWQDESNDLW
                     TTYQRIQENLIKGGLSGRNAKGGRSHTRAVRGIDGDVKLNRALWVMAEALLTQLQ"
     misc_feature    complement(267220..267897)
                     /gene="yafZ"
                     /locus_tag="b0252"
                     /gene_synonym="ECK0254; JW0242"
                     /note="Domain of unknown function (DUF932); Region:
                     DUF932; pfam06067"
                     /db_xref="CDD:253543"
     gene            complement(268097..268960)
                     /gene="ykfA"
                     /locus_tag="b0253"
                     /gene_synonym="ECK0255; JW0243"
                     /db_xref="EcoGene:EG13339"
                     /db_xref="GeneID:949004"
     CDS             complement(268097..268960)
                     /gene="ykfA"
                     /locus_tag="b0253"
                     /gene_synonym="ECK0255; JW0243"
                     /function="Phage or Prophage Related"
                     /note="putative GTP-binding protein"
                     /codon_start=1
                     /transl_table=11
                     /product="CP4-6 prophage; putative GTP-binding protein"
                     /protein_id="NP_414787.4"
                     /db_xref="GI:90111103"
                     /db_xref="ASAP:ABE-0000858"
                     /db_xref="UniProtKB/Swiss-Prot:P75678"
                     /db_xref="EcoGene:EG13339"
                     /db_xref="GeneID:949004"
                     /translation="MNNSEGLKSFQQSLADLPQWVSERLLQQINQLTNYEPVIGIMGK
                     TGVGKSSLCNALFAGDISPVSDVAACTREPLRFRLQVGDRYITLMDLPGVGESGARDT
                     EYAALYREQLPRLDLVLWLIKADDRALTVDEHFYHQVIGEVYRHKVLFVISQSDKAEP
                     TSGGGQLSTAQKQNISRKICLLHELFQPVHPVCAVSVRLQWGLKVMAERMIKCLPREA
                     TSPVVSQLHPSFRTTVVREQARSDFGETVGAVLDSISAFPLIPAPVRAVIQAVRTTVV
                     SVARAVWDFFF"
     misc_feature    complement(268100..268960)
                     /gene="ykfA"
                     /locus_tag="b0253"
                     /gene_synonym="ECK0255; JW0243"
                     /note="Predicted GTPase [General function prediction
                     only]; Region: COG3596"
                     /db_xref="CDD:226124"
     misc_feature    complement(268319..268843)
                     /gene="ykfA"
                     /locus_tag="b0253"
                     /gene_synonym="ECK0255; JW0243"
                     /note="YfjP GTPase; Region: YfjP; cd11383"
                     /db_xref="CDD:206743"
     misc_feature    complement(268811..268834)
                     /gene="ykfA"
                     /locus_tag="b0253"
                     /gene_synonym="ECK0255; JW0243"
                     /note="G1 box; other site"
                     /db_xref="CDD:206743"
     misc_feature    complement(order(268370..268375,268493..268495,
                     268499..268504,268808..268825))
                     /gene="ykfA"
                     /locus_tag="b0253"
                     /gene_synonym="ECK0255; JW0243"
                     /note="GTP/Mg2+ binding site [chemical binding]; other
                     site"
                     /db_xref="CDD:206743"
     misc_feature    complement(268739..268753)
                     /gene="ykfA"
                     /locus_tag="b0253"
                     /gene_synonym="ECK0255; JW0243"
                     /note="Switch I region; other site"
                     /db_xref="CDD:206743"
     misc_feature    complement(268748..268750)
                     /gene="ykfA"
                     /locus_tag="b0253"
                     /gene_synonym="ECK0255; JW0243"
                     /note="G2 box; other site"
                     /db_xref="CDD:206743"
     misc_feature    complement(order(268619..268621,268679..268696))
                     /gene="ykfA"
                     /locus_tag="b0253"
                     /gene_synonym="ECK0255; JW0243"
                     /note="Switch II region; other site"
                     /db_xref="CDD:206743"
     misc_feature    complement(268682..268693)
                     /gene="ykfA"
                     /locus_tag="b0253"
                     /gene_synonym="ECK0255; JW0243"
                     /note="G3 box; other site"
                     /db_xref="CDD:206743"
     misc_feature    complement(268493..268504)
                     /gene="ykfA"
                     /locus_tag="b0253"
                     /gene_synonym="ECK0255; JW0243"
                     /note="G4 box; other site"
                     /db_xref="CDD:206743"
     misc_feature    complement(268367..268375)
                     /gene="ykfA"
                     /locus_tag="b0253"
                     /gene_synonym="ECK0255; JW0243"
                     /note="G5 box; other site"
                     /db_xref="CDD:206743"
     gene            complement(269289..270182)
                     /gene="perR"
                     /locus_tag="b0254"
                     /gene_synonym="ECK0256; JW0244"
                     /db_xref="EcoGene:EG13340"
                     /db_xref="GeneID:945417"
     CDS             complement(269289..270182)
                     /gene="perR"
                     /locus_tag="b0254"
                     /gene_synonym="ECK0256; JW0244"
                     /function="Phage or Prophage Related"
                     /note="peroxide resistance protein"
                     /codon_start=1
                     /transl_table=11
                     /product="CP4-6 prophage; putative DNA-binding
                     transcriptional regulator"
                     /protein_id="NP_414788.1"
                     /db_xref="GI:16128239"
                     /db_xref="ASAP:ABE-0000862"
                     /db_xref="UniProtKB/Swiss-Prot:Q57083"
                     /db_xref="EcoGene:EG13340"
                     /db_xref="GeneID:945417"
                     /translation="MKLLAKAPLNLLRAFEAAGRTGAFALAASELELSPSAISHAIRK
                     LENLLDVRLFQRSTREITLTKEGEILLEHIQRGFNELQQGLALVTADESRPLRLHTAP
                     SFAHQWLLPRLGKFIRENPSIDLRLSASTEYARFEQDDFDLDIVYGEPRPSPYEKIPL
                     AVEELTPLCSPQLAERLKKPEDLYALTLIQCDVQLYQWKGWFEANKMTPPNNYGLRFD
                     RSFMAIAAAVDGLGVVLESKLLAEREIASGKLVCPLVNSTSEIHYIGHYLVFPQHQHM
                     HSALDVFKTWLLNELNLGKIR"
     misc_feature    complement(269307..270161)
                     /gene="perR"
                     /locus_tag="b0254"
                     /gene_synonym="ECK0256; JW0244"
                     /note="DNA-binding transcriptional activator GcvA;
                     Provisional; Region: PRK11139"
                     /db_xref="CDD:182990"
     misc_feature    complement(269979..270158)
                     /gene="perR"
                     /locus_tag="b0254"
                     /gene_synonym="ECK0256; JW0244"
                     /note="Bacterial regulatory helix-turn-helix protein, lysR
                     family; Region: HTH_1; pfam00126"
                     /db_xref="CDD:249610"
     misc_feature    complement(269322..269900)
                     /gene="perR"
                     /locus_tag="b0254"
                     /gene_synonym="ECK0256; JW0244"
                     /note="The C-terminal substrate domain of LysR-type GcdR,
                     TrPI, HvR and beta-lactamase regulators, and that of other
                     closely related homologs; contains the type 2 periplasmic
                     binding fold; Region: PBP2_GcdR_TrpI_HvrB_AmpR_like;
                     cd08432"
                     /db_xref="CDD:176123"
     misc_feature    complement(order(269796..269816,269820..269873,
                     269877..269900))
                     /gene="perR"
                     /locus_tag="b0254"
                     /gene_synonym="ECK0256; JW0244"
                     /note="dimerization interface [polypeptide binding]; other
                     site"
                     /db_xref="CDD:176123"
     misc_feature    complement(order(269463..269465,269523..269531,
                     269871..269873,269877..269882))
                     /gene="perR"
                     /locus_tag="b0254"
                     /gene_synonym="ECK0256; JW0244"
                     /note="substrate binding pocket [chemical binding]; other
                     site"
                     /db_xref="CDD:176123"
     mobile_element  270206..270540
                     /mobile_element_type="insertion sequence:IS911A"
     gene            join(270278..270535,271764..272189)
                     /gene="insN"
                     /locus_tag="b4587"
                     /gene_synonym="ECK0257; insN1; insO; ORFAB"
                     /pseudo
                     /db_xref="EcoGene:EG40014"
                     /db_xref="GeneID:5061501"
     CDS             join(270278..270535,271764..272189)
                     /gene="insN"
                     /locus_tag="b4587"
                     /gene_synonym="ECK0257; insN1; insO; ORFAB"
                     /experiment="N-terminus verified by Edman degradation:
                     PMID 1660923"
                     /note="pseudogene, IS911 transposase A;IS, phage, Tn;
                     Transposon-related functions; extrachromosomal; transposon
                     related"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /db_xref="ASAP:ABE-0000867"
                     /db_xref="UniProtKB/Swiss-Prot:P75679"
                     /db_xref="EcoGene:EG40014"
                     /db_xref="GeneID:5061501"
     mobile_element  270541..271761
                     /mobile_element_type="insertion sequence:IS30A"
     gene            270603..271754
                     /gene="insI1"
                     /locus_tag="b0256"
                     /gene_synonym="ECK0258"
                     /db_xref="EcoGene:EG40009"
                     /db_xref="GeneID:949005"
     CDS             270603..271754
                     /gene="insI1"
                     /locus_tag="b0256"
                     /gene_synonym="ECK0258"
                     /function="IS, phage, Tn; Transposon-related functions;
                     extrachromosomal; transposon related"
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 transposase"
                     /protein_id="NP_414790.1"
                     /db_xref="GI:16128241"
                     /db_xref="ASAP:ABE-0000871"
                     /db_xref="UniProtKB/Swiss-Prot:P0CF88"
                     /db_xref="EcoGene:EG40009"
                     /db_xref="GeneID:949005"
                     /translation="MRRTFTAEEKASVFELWKNGTGFSEIANILGSKPGTIFTMLRDT
                     GGIKPHERKRAVAHLTLSEREEIRAGLSAKMSIRAIATALNRSPSTISREVQRNRGRR
                     YYKAVDANNRANRMAKRPKPCLLDQNLPLRKLVLEKLEMKWSPEQISGWLRRTKPRQK
                     TLRISPETIYKTLYFRSREALHHLNIQHLRRSHSLRHGRRHTRKGERGTINIVNGTPI
                     HERSRNIDNRRSLGHWEGDLVSGTKNSHIATLVDRKSRYTIIVRLRGKDSVSVNQALT
                     DKFLSLPSELRKSLTWDRGMELARHLEFTVSTGVKVYFCDPQSPWQRGTNENTNGLIR
                     QYFPKKTCLAQYTQHELDLVAAQLNNRPRKTLKFKTPKEIIERGVALTD"
     misc_feature    270756..271751
                     /gene="insI1"
                     /locus_tag="b0256"
                     /gene_synonym="ECK0258"
                     /note="Transposase and inactivated derivatives, IS30
                     family [DNA replication, recombination, and repair];
                     Region: Tra8; COG2826"
                     /db_xref="CDD:225382"
     misc_feature    270774..270896
                     /gene="insI1"
                     /locus_tag="b0256"
                     /gene_synonym="ECK0258"
                     /note="Helix-turn-helix domain; Region: HTH_38; pfam13936"
                     /db_xref="CDD:258198"
     misc_feature    270870..271121
                     /gene="insI1"
                     /locus_tag="b0256"
                     /gene_synonym="ECK0258"
                     /note="Homeodomain-like domain; Region: HTH_32; pfam13565"
                     /db_xref="CDD:257882"
     misc_feature    271284..271613
                     /gene="insI1"
                     /locus_tag="b0256"
                     /gene_synonym="ECK0258"
                     /note="Integrase core domain; Region: rve; pfam00665"
                     /db_xref="CDD:250040"
     mobile_element  271762..272190
                     /mobile_element_type="insertion sequence:IS911A"
     gene            272580..272654
                     /gene="eyeA"
                     /locus_tag="b4690"
                     /gene_synonym="ECK4506; I001"
                     /db_xref="EcoGene:EG31183"
                     /db_xref="GeneID:7751631"
     ncRNA           272580..272654
                     /gene="eyeA"
                     /locus_tag="b4690"
                     /gene_synonym="ECK4506; I001"
                     /ncRNA_class="other"
                     /product="novel sRNA, function unknown, CP4-6 propahge"
                     /db_xref="EcoGene:EG31183"
                     /db_xref="GeneID:7751631"
     gene            272847..273954
                     /gene="ykfC"
                     /locus_tag="b0258"
                     /gene_synonym="ECK0260; JW5813"
                     /pseudo
                     /db_xref="EcoGene:EG13341"
                     /db_xref="GeneID:944940"
     CDS             272847..273954
                     /gene="ykfC"
                     /locus_tag="b0258"
                     /gene_synonym="ECK0260; JW5813"
                     /note="CP4-6 prophage; conserved protein;Phage or Prophage
                     Related"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /db_xref="ASAP:ABE-0000885"
                     /db_xref="UniProtKB/Swiss-Prot:Q47688"
                     /db_xref="EcoGene:EG13341"
                     /db_xref="GeneID:944940"
     mobile_element  complement(273955..275149)
                     /mobile_element_type="insertion sequence:IS5A"
     gene            complement(274101..275117)
                     /gene="insH1"
                     /locus_tag="b0259"
                     /gene_synonym="ECK0261"
                     /db_xref="EcoGene:EG40008"
                     /db_xref="GeneID:944941"
     CDS             complement(274101..275117)
                     /gene="insH1"
                     /locus_tag="b0259"
                     /gene_synonym="ECK0261"
                     /function="IS, phage, Tn; Transposon-related functions;
                     extrachromosomal; transposon related"
                     /codon_start=1
                     /transl_table=11
                     /product="IS5 transposase and trans-activator"
                     /protein_id="NP_414793.1"
                     /db_xref="GI:16128244"
                     /db_xref="ASAP:ABE-0000888"
                     /db_xref="UniProtKB/Swiss-Prot:P0CE49"
                     /db_xref="EcoGene:EG40008"
                     /db_xref="GeneID:944941"
                     /translation="MFVIWSHRTGFIMSHQLTFADSEFSSKRRQTRKEIFLSRMEQIL
                     PWQNMVEVIEPFYPKAGNGRRPYPLETMLRIHCMQHWYNLSDGAMEDALYEIASMRLF
                     ARLSLDSALPDRTTIMNFRHLLEQHQLARQLFKTINRWLAEAGVMMTQGTLVDATIIE
                     APSSTKNKEQQRDPEMHQTKKGNQWHFGMKAHIGVDAKSGLTHSLVTTAANEHDLNQL
                     GNLLHGEEQFVSADAGYQGAPQREELAEVDVDWLIAERPGKVRTLKQHPRKNKTAINI
                     EYMKASIRARVEHPFRIIKRQFGFVKARYKGLLKNDNQLAMLFTLANLFRADQMIRQW
                     ERSH"
     misc_feature    complement(274704..274931)
                     /gene="insH1"
                     /locus_tag="b0259"
                     /gene_synonym="ECK0261"
                     /note="Transposase domain (DUF772); Region: DUF772;
                     pfam05598"
                     /db_xref="CDD:253271"
     misc_feature    complement(274116..274895)
                     /gene="insH1"
                     /locus_tag="b0259"
                     /gene_synonym="ECK0261"
                     /note="Transposase and inactivated derivatives, IS5 family
                     [DNA replication, recombination, and repair]; Region:
                     COG3039"
                     /db_xref="CDD:225581"
     misc_feature    complement(274149..274658)
                     /gene="insH1"
                     /locus_tag="b0259"
                     /gene_synonym="ECK0261"
                     /note="DDE superfamily endonuclease; Region: DDE_Tnp_4;
                     cl17710"
                     /db_xref="CDD:266781"
     misc_feature    complement(274146..>274346)
                     /gene="insH1"
                     /locus_tag="b0259"
                     /gene_synonym="ECK0261"
                     /note="Transposase DDE domain; Region: DDE_Tnp_1_6;
                     pfam13751"
                     /db_xref="CDD:258043"
     gene            275325..276728
                     /gene="mmuP"
                     /locus_tag="b0260"
                     /gene_synonym="ECK0262; JW5027; ykfD"
                     /db_xref="EcoGene:EG13342"
                     /db_xref="GeneID:946284"
     CDS             275325..276728
                     /gene="mmuP"
                     /locus_tag="b0260"
                     /gene_synonym="ECK0262; JW5027; ykfD"
                     /function="Phage or Prophage Related"
                     /GO_component="GO:0009274 - peptidoglycan-based cell wall"
                     /GO_component="GO:0019866 - organelle inner membrane"
                     /GO_process="GO:0009086 - methionine biosynthetic process"
                     /codon_start=1
                     /transl_table=11
                     /product="CP4-6 prophage; putative S-methylmethionine
                     transporter"
                     /protein_id="NP_414794.4"
                     /db_xref="GI:90111105"
                     /db_xref="ASAP:ABE-0000893"
                     /db_xref="UniProtKB/Swiss-Prot:Q47689"
                     /db_xref="EcoGene:EG13342"
                     /db_xref="GeneID:946284"
                     /translation="MQTTQQNAPLKRTMKTRHLIMLSLGGVIGTGLFFNTGYIISTTG
                     AAGTLLAYLIGALVVWLVMQCLGELSVAMPETGAFHVYAARYLGPATGYTVAWLYWLT
                     WTVALGSSFTAAGFCMQYWFPQVPVWVWCVVFCAIIFGLNVISTRFFAEGEFWFSLVK
                     VVTIIAFIILGGAAIFGFIPMQDGSPAPGLSNITAEGWFPHGGLPILMTMVAVNFAFS
                     GTELIGIAAGETENPRKVIPVAIRTTIARLIIFFIGTVFVLAALIPMQQVGVEKSPFV
                     LVFEKVGIPYAADIFNFVILTAILSAANSGLYASGRMLWSLSNERTLPACFARVTKNG
                     VPLTALSVSMLGGVLALFSSVVAPDTVFVALSAISGFAVVAVWLSICASHFVFRRRHL
                     QQGKALSELHYRAPWYPLVPVLGFVLCLVACVGLAFDPAQRIALWCGLPFVALCYGAY
                     FLTQPRNAKQEPEHVAE"
     misc_feature    275325..276725
                     /gene="mmuP"
                     /locus_tag="b0260"
                     /gene_synonym="ECK0262; JW5027; ykfD"
                     /note="S-methylmethionine transporter; Provisional;
                     Region: PRK11387"
                     /db_xref="CDD:236904"
     misc_feature    275412..>276359
                     /gene="mmuP"
                     /locus_tag="b0260"
                     /gene_synonym="ECK0262; JW5027; ykfD"
                     /note="Transmembrane amino acid transporter protein;
                     Region: Aa_trans; cl17468"
                     /db_xref="CDD:266708"
     gene            276715..277647
                     /gene="mmuM"
                     /locus_tag="b0261"
                     /gene_synonym="ECK0263; JW0253; yagD"
                     /db_xref="EcoGene:EG13343"
                     /db_xref="GeneID:946143"
     CDS             276715..277647
                     /gene="mmuM"
                     /locus_tag="b0261"
                     /gene_synonym="ECK0263; JW0253; yagD"
                     /EC_number="2.1.1.10"
                     /function="Phage or Prophage Related"
                     /GO_process="GO:0006071 - glycerol metabolic process"
                     /GO_process="GO:0009086 - methionine biosynthetic process"
                     /codon_start=1
                     /transl_table=11
                     /product="CP4-6 prophage; S-methylmethionine:homocysteine
                     methyltransferase"
                     /protein_id="NP_414795.1"
                     /db_xref="GI:16128246"
                     /db_xref="ASAP:ABE-0000895"
                     /db_xref="UniProtKB/Swiss-Prot:Q47690"
                     /db_xref="EcoGene:EG13343"
                     /db_xref="GeneID:946143"
                     /translation="MSQNNPLRALLDKQDILLLDGAMATELEARGCNLADSLWSAKVL
                     VENPELIREVHLDYYRAGAQCAITASYQATPAGFAARGLDEAQSKALIGKSVELARKA
                     REAYLAENPQAGTLLVAGSVGPYGAYLADGSEYRGDYHCSVEAFQAFHRPRVEALLDA
                     GADLLACETLPNFSEIEALAELLTAYPRARAWFSFTLRDSEHLSDGTPLRDVVALLAG
                     YPQVVALGINCIALENTTAALQHLHGLTVLPLVVYPNSGEHYDAVSKTWHHHGEHCAQ
                     LADYLPQWQAAGARLIGGCCRTTPADIAALKARS"
     misc_feature    276724..277641
                     /gene="mmuM"
                     /locus_tag="b0261"
                     /gene_synonym="ECK0263; JW0253; yagD"
                     /note="homocysteine methyltransferase; Provisional;
                     Region: mmuM; PRK09485"
                     /db_xref="CDD:181899"
     repeat_region   277675..277741
                     /note="REP22 (repetitive extragenic palindromic) element;
                     contains 2 REP sequences"
     gene            complement(277756..278802)
                     /gene="afuC"
                     /locus_tag="b0262"
                     /gene_synonym="ECK0264; fbpC; JW0254; yagC"
                     /db_xref="EcoGene:EG12340"
                     /db_xref="GeneID:947676"
     CDS             complement(277756..278802)
                     /gene="afuC"
                     /locus_tag="b0262"
                     /gene_synonym="ECK0264; fbpC; JW0254; yagC"
                     /function="putative transport; Not classified; Phage or
                     Prophage Related"
                     /note="putative ATP-binding component of a transport
                     system"
                     /codon_start=1
                     /transl_table=11
                     /product="CP4-6 prophage; putative ferric transporter
                     subunit"
                     /protein_id="NP_414796.2"
                     /db_xref="GI:90111106"
                     /db_xref="ASAP:ABE-0000898"
                     /db_xref="UniProtKB/Swiss-Prot:P37009"
                     /db_xref="EcoGene:EG12340"
                     /db_xref="GeneID:947676"
                     /translation="MTQKNFVELRNVTKRFGSNTVIDNINLTIPQGQMVTLLGPSGCG
                     KTTILRLVAGLEKPSEGQIFIDGEDVTHRSIQQRDICMVFQSYALFPHMSLGENVGYG
                     LKMLGVPRAELKARVKEALAMVDLEGFEDRFVDQISGGQQQRVALARALILKPKVLLF
                     DEPLSNLDANLRRSMRDKIRELQKQFDITSLYVTHDQSEAFAVSDTVLVMNKGHIMQI
                     GSPQDLYRQPASRFMASFMGDANLFPATFSDGYVDIYGYHLPRPLHFGTQGEGMVGVR
                     PEAITLSDRGEESQRCVIRHVAYMGPQYEVTVEWHGQEILLQVNATRLQPDVGEQYYL
                     EIHPYGMFVLADAA"
     misc_feature    complement(277759..278802)
                     /gene="afuC"
                     /locus_tag="b0262"
                     /gene_synonym="ECK0264; fbpC; JW0254; yagC"
                     /note="ferric transporter ATP-binding subunit;
                     Provisional; Region: fbpC; PRK11432"
                     /db_xref="CDD:183133"
     misc_feature    complement(278089..278784)
                     /gene="afuC"
                     /locus_tag="b0262"
                     /gene_synonym="ECK0264; fbpC; JW0254; yagC"
                     /note="ATP-binding cassette transporter nucleotide-binding
                     domain; Region: ABC_ATPase; cl17201"
                     /db_xref="CDD:266551"
     misc_feature    complement(278665..278688)
                     /gene="afuC"
                     /locus_tag="b0262"
                     /gene_synonym="ECK0264; fbpC; JW0254; yagC"
                     /note="Walker A/P-loop; other site"
                     /db_xref="CDD:213179"
     misc_feature    complement(order(278218..278220,278317..278322,
                     278548..278550,278662..278670,278674..278679))
                     /gene="afuC"
                     /locus_tag="b0262"
                     /gene_synonym="ECK0264; fbpC; JW0254; yagC"
                     /note="ATP binding site [chemical binding]; other site"
                     /db_xref="CDD:213179"
     misc_feature    complement(278548..278559)
                     /gene="afuC"
                     /locus_tag="b0262"
                     /gene_synonym="ECK0264; fbpC; JW0254; yagC"
                     /note="Q-loop/lid; other site"
                     /db_xref="CDD:213179"
     misc_feature    complement(278365..278394)
                     /gene="afuC"
                     /locus_tag="b0262"
                     /gene_synonym="ECK0264; fbpC; JW0254; yagC"
                     /note="ABC transporter signature motif; other site"
                     /db_xref="CDD:213179"
     misc_feature    complement(278317..278334)
                     /gene="afuC"
                     /locus_tag="b0262"
                     /gene_synonym="ECK0264; fbpC; JW0254; yagC"
                     /note="Walker B; other site"
                     /db_xref="CDD:213179"
     misc_feature    complement(278299..278310)
                     /gene="afuC"
                     /locus_tag="b0262"
                     /gene_synonym="ECK0264; fbpC; JW0254; yagC"
                     /note="D-loop; other site"
                     /db_xref="CDD:213179"
     misc_feature    complement(278212..278232)
                     /gene="afuC"
                     /locus_tag="b0262"
                     /gene_synonym="ECK0264; fbpC; JW0254; yagC"
                     /note="H-loop/switch region; other site"
                     /db_xref="CDD:213179"
     misc_feature    complement(277771..277986)
                     /gene="afuC"
                     /locus_tag="b0262"
                     /gene_synonym="ECK0264; fbpC; JW0254; yagC"
                     /note="TOBE domain; Region: TOBE_2; pfam08402"
                     /db_xref="CDD:254779"
     gene            complement(278814..279161)
                     /gene="afuB"
                     /locus_tag="b0263"
                     /gene_synonym="ECK0265; fbpB; JW0255"
                     /pseudo
                     /db_xref="EcoGene:EG14277"
                     /db_xref="GeneID:947073"
     CDS             complement(278814..279161)
                     /gene="afuB"
                     /locus_tag="b0263"
                     /gene_synonym="ECK0265; fbpB; JW0255"
                     /note="pseudogene, CP4-6 prophage; ferric iron ABC
                     transporter permease gene fragment;Phage or Prophage
                     Related"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /db_xref="ASAP:ABE-0000900"
                     /db_xref="UniProtKB/Swiss-Prot:P75681"
                     /db_xref="EcoGene:EG14277"
                     /db_xref="GeneID:947073"
     mobile_element  complement(279163..279930)
                     /mobile_element_type="insertion sequence:IS1B"
     gene            complement(279178..279681)
                     /gene="insB1"
                     /locus_tag="b0264"
                     /gene_synonym="ECK0022"
                     /db_xref="EcoGene:EG40002"
                     /db_xref="GeneID:947698"
     CDS             complement(279178..279681)
                     /gene="insB1"
                     /locus_tag="b0264"
                     /gene_synonym="ECK0022"
                     /function="IS, phage, Tn; Transposon-related functions;
                     extrachromosomal; transposon related"
                     /codon_start=1
                     /transl_table=11
                     /product="IS1 transposase B"
                     /protein_id="NP_414798.1"
                     /db_xref="GI:16128249"
                     /db_xref="ASAP:ABE-0000906"
                     /db_xref="UniProtKB/Swiss-Prot:P0CF26"
                     /db_xref="EcoGene:EG40002"
                     /db_xref="GeneID:947698"
                     /translation="MPGNRPHYGRWPQHDFPPFKKLRPQSVTSRIQPGSDVIVCAEMD
                     EQWGYVGAKSRQRWLFYAYDRLRKTVVAHVFGERTMATLGRLMSLLSPFDVVIWMTDG
                     WPLYESRLKGKLHVISKRYTQRIERHNLNLRQHLARLGRKSLSFSKSVEQHDKVIGHY
                     LNIKHYQ"
     misc_feature    complement(279181..279570)
                     /gene="insB1"
                     /locus_tag="b0264"
                     /gene_synonym="ECK0022"
                     /note="IS1 transposase; Region: DDE_Tnp_IS1; pfam03400"
                     /db_xref="CDD:112225"
     gene            complement(279600..279875)
                     /gene="insA"
                     /locus_tag="b0265"
                     /gene_synonym="ECK4521"
                     /note="insA2"
                     /db_xref="EcoGene:EG40001"
                     /db_xref="GeneID:944946"
     CDS             complement(279600..279875)
                     /gene="insA"
                     /locus_tag="b0265"
                     /gene_synonym="ECK4521"
                     /function="IS, phage, Tn; Transposon-related functions;
                     extrachromosomal; transposon related"
                     /codon_start=1
                     /transl_table=11
                     /product="IS1 repressor TnpA"
                     /protein_id="NP_414799.1"
                     /db_xref="GI:16128250"
                     /db_xref="ASAP:ABE-0000909"
                     /db_xref="UniProtKB/Swiss-Prot:P0CF08"
                     /db_xref="EcoGene:EG40001"
                     /db_xref="GeneID:944946"
                     /translation="MASVSISCPSCSATDGVVRNGKSTAGHQRYLCSHCRKTWQLQFT
                     YTASQPGTHQKIIDMAMNGVGCRATARIMGVGLNTIFRHLKNSGRSR"
     misc_feature    complement(279603..279875)
                     /gene="insA"
                     /locus_tag="b0265"
                     /gene_synonym="ECK4521"
                     /note="Transposase and inactivated derivatives [DNA
                     replication, recombination, and repair]; Region: COG3677"
                     /db_xref="CDD:226202"
     misc_feature    complement(279768..279875)
                     /gene="insA"
                     /locus_tag="b0265"
                     /gene_synonym="ECK4521"
                     /note="InsA N-terminal domain; Region: Zn_Tnp_IS1;
                     pfam03811"
                     /db_xref="CDD:190760"
     misc_feature    complement(279612..279749)
                     /gene="insA"
                     /locus_tag="b0265"
                     /gene_synonym="ECK4521"
                     /note="InsA C-terminal domain; Region: HTH_Tnp_IS1;
                     pfam12759"
                     /db_xref="CDD:257276"
     mobile_element  279931..280111
                     /mobile_element_type="insertion sequence:IS30B"
     gene            279931..280104
                     /gene="insI1"
                     /locus_tag="b4708"
                     /gene_synonym="ECK0258"
                     /pseudo
                     /db_xref="EcoGene:EG40009"
                     /db_xref="GeneID:14678508"
     CDS             279931..280104
                     /gene="insI1"
                     /locus_tag="b4708"
                     /gene_synonym="ECK0258"
                     /note="IS30 transposase;IS, phage, Tn; Transposon-related
                     functions; extrachromosomal; transposon related"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /db_xref="EcoGene:EG40009"
                     /db_xref="GeneID:14678508"
     mobile_element  complement(280114..280425)
                     /mobile_element_type="insertion sequence:ISX"
     gene            complement(280114..280362)
                     /gene="insX"
                     /locus_tag="b4505"
                     /gene_synonym="ECK4473; ykgN"
                     /pseudo
                     /db_xref="EcoGene:EG14418"
                     /db_xref="GeneID:1450237"
     CDS             complement(280114..280362)
                     /gene="insX"
                     /locus_tag="b4505"
                     /gene_synonym="ECK4473; ykgN"
                     /note="pseudogene, IS3 family transposase family"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /db_xref="ASAP:ABE-0285026"
                     /db_xref="UniProtKB/Swiss-Prot:Q79E92"
                     /db_xref="EcoGene:EG14418"
                     /db_xref="GeneID:1450237"
     gene            complement(280427..280735)
                     /gene="yagB"
                     /locus_tag="b0266"
                     /gene_synonym="ECK0267; JW0259"
                     /pseudo
                     /db_xref="EcoGene:EG12339"
                     /db_xref="GeneID:944944"
     CDS             complement(280427..280735)
                     /gene="yagB"
                     /locus_tag="b0266"
                     /gene_synonym="ECK0267; JW0259"
                     /note="pseudogene, CP4-6 prophage;Phage or Prophage
                     Related"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /db_xref="ASAP:ABE-0000912"
                     /db_xref="UniProtKB/Swiss-Prot:P37008"
                     /db_xref="EcoGene:EG12339"
                     /db_xref="GeneID:944944"
     gene            complement(280829..281983)
                     /gene="yagA"
                     /locus_tag="b0267"
                     /gene_synonym="ECK0268; JW0260"
                     /db_xref="EcoGene:EG12338"
                     /db_xref="GeneID:944937"
     CDS             complement(280829..281983)
                     /gene="yagA"
                     /locus_tag="b0267"
                     /gene_synonym="ECK0268; JW0260"
                     /function="Phage or Prophage Related"
                     /codon_start=1
                     /transl_table=11
                     /product="CP4-6 prophage; putative DNA-binding
                     transcriptional regulator"
                     /protein_id="NP_414801.1"
                     /db_xref="GI:16128252"
                     /db_xref="ASAP:ABE-0000915"
                     /db_xref="UniProtKB/Swiss-Prot:P37007"
                     /db_xref="EcoGene:EG12338"
                     /db_xref="GeneID:944937"
                     /translation="MESLMPWDARDTMSLRTEFVLFASQDGANIRSLCRRFGISPATG
                     YKWLQRWAQEGAAGLQDRPRIPHHSPNRSSDDITALLRMAHDRHERWGARKIKRWLED
                     QGHTMPAFSTVHNLMARHGLLPGASPGIPATGRFEHDAPNRLWQMDFKGHFPFGGGRC
                     HPLTLLDDHSRFSLCLAHCTDERRETVQQQLVSVFERYGLPDRMTMDNGSPWGDTTGT
                     WTALELWLMRLGIRVGHSRPYHPQTQGKLERFHRSLKAEVLQGKWFADSGELQRAFDH
                     WRTVYNLERPHEALDMAVPGSRYQPSARQYSGNTTPPEYDEGVMVRKVDISGKLSVKG
                     VSLSAGKAFRGERVGLKEMQEDGSYEVWWYSTKVGVIDLKKKSITMGKGC"
     misc_feature    complement(<281714..281950)
                     /gene="yagA"
                     /locus_tag="b0267"
                     /gene_synonym="ECK0268; JW0260"
                     /note="Transposase and inactivated derivatives [DNA
                     replication, recombination, and repair]; Region: COG2963"
                     /db_xref="CDD:225511"
     misc_feature    complement(281792..281926)
                     /gene="yagA"
                     /locus_tag="b0267"
                     /gene_synonym="ECK0268; JW0260"
                     /note="Helix-turn-helix domain; Region: HTH_28; pfam13518"
                     /db_xref="CDD:257838"
     misc_feature    complement(281633..281857)
                     /gene="yagA"
                     /locus_tag="b0267"
                     /gene_synonym="ECK0268; JW0260"
                     /note="Homeodomain-like domain; Region: HTH_32; pfam13565"
                     /db_xref="CDD:257882"
     misc_feature    complement(281069..281782)
                     /gene="yagA"
                     /locus_tag="b0267"
                     /gene_synonym="ECK0268; JW0260"
                     /note="Transposase and inactivated derivatives [DNA
                     replication, recombination, and repair]; Region: Tra5;
                     COG2801"
                     /db_xref="CDD:225361"
     misc_feature    complement(281210..281575)
                     /gene="yagA"
                     /locus_tag="b0267"
                     /gene_synonym="ECK0268; JW0260"
                     /note="Integrase core domain; Region: rve; pfam00665"
                     /db_xref="CDD:250040"
     misc_feature    complement(281099..281299)
                     /gene="yagA"
                     /locus_tag="b0267"
                     /gene_synonym="ECK0268; JW0260"
                     /note="Integrase core domain; Region: rve_3; pfam13683"
                     /db_xref="CDD:257986"
     gene            282278..283186
                     /gene="yagE"
                     /locus_tag="b0268"
                     /gene_synonym="ECK0269; JW0261"
                     /db_xref="EcoGene:EG13344"
                     /db_xref="GeneID:944925"
     CDS             282278..283186
                     /gene="yagE"
                     /locus_tag="b0268"
                     /gene_synonym="ECK0269; JW0261"
                     /function="Phage or Prophage Related"
                     /note="putative lyase/synthase"
                     /codon_start=1
                     /transl_table=11
                     /product="2-keto-3-deoxy gluconate (KDG) aldolase; CP4-6
                     prophage"
                     /protein_id="NP_414802.2"
                     /db_xref="GI:345452715"
                     /db_xref="ASAP:ABE-0000921"
                     /db_xref="UniProtKB/Swiss-Prot:P75682"
                     /db_xref="EcoGene:EG13344"
                     /db_xref="GeneID:944925"
                     /translation="MPQSALFTGIIPPVSTIFTADGQLDKPGTAALIDDLIKAGVDGL
                     FFLGSGGEFSQLGAEERKAIARFAIDHVDRRVPVLIGTGGTNARETIELSQHAQQAGA
                     DGIVVINPYYWKVSEANLIRYFEQVADSVTLPVMLYNFPALTGQDLTPALVKTLADSR
                     SNIIGIKDTIDSVAHLRSMIHTVKGAHPHFTVLCGYDDHLFNTLLLGGDGAISASGNF
                     APQVSVNLLKAWRDGDVAKAAGYHQTLLQIPQMYQLDTPFVNVIKEAIVLCGRPVSTH
                     VLPPASPLDEPRKAQLKTLLQQLKLC"
     misc_feature    282305..283147
                     /gene="yagE"
                     /locus_tag="b0268"
                     /gene_synonym="ECK0269; JW0261"
                     /note="Dihydrodipicolinate synthase family; Region:
                     DHDPS-like; cd00408"
                     /db_xref="CDD:188630"
     misc_feature    order(282314..282316,282410..282412,282419..282427,
                     282689..282691,282776..282778)
                     /gene="yagE"
                     /locus_tag="b0268"
                     /gene_synonym="ECK0269; JW0261"
                     /note="inhibitor site; inhibition site"
                     /db_xref="CDD:188630"
     misc_feature    order(282410..282412,282419..282427,282689..282691,
                     282776..282778,282911..282913)
                     /gene="yagE"
                     /locus_tag="b0268"
                     /gene_synonym="ECK0269; JW0261"
                     /note="active site"
                     /db_xref="CDD:188630"
     misc_feature    order(282422..282424,282437..282442,282533..282538,
                     282608..282613,282632..282634,282644..282646,
                     283112..283117)
                     /gene="yagE"
                     /locus_tag="b0268"
                     /gene_synonym="ECK0269; JW0261"
                     /note="dimer interface [polypeptide binding]; other site"
                     /db_xref="CDD:188630"
     misc_feature    282776..282778
                     /gene="yagE"
                     /locus_tag="b0268"
                     /gene_synonym="ECK0269; JW0261"
                     /note="catalytic residue [active]"
                     /db_xref="CDD:188630"
     gene            283201..285168
                     /gene="yagF"
                     /locus_tag="b0269"
                     /gene_synonym="ECK0270; JW0262"
                     /db_xref="EcoGene:EG13345"
                     /db_xref="GeneID:944928"
     CDS             283201..285168
                     /gene="yagF"
                     /locus_tag="b0269"
                     /gene_synonym="ECK0270; JW0262"
                     /function="Phage or Prophage Related"
                     /note="putative dehydratase"
                     /codon_start=1
                     /transl_table=11
                     /product="CP4-6 prophage; dehydratase family protein"
                     /protein_id="NP_414803.1"
                     /db_xref="GI:16128254"
                     /db_xref="ASAP:ABE-0000923"
                     /db_xref="UniProtKB/Swiss-Prot:P77596"
                     /db_xref="EcoGene:EG13345"
                     /db_xref="GeneID:944928"
                     /translation="MTIEKIFTPQDDAFYAVITHAAGPQGALPLTPQMLMESPSGNLF
                     GMTQNAGMGWDANKLTGKEVLIIGTQGGIRAGDGRPIALGYHTGHWEIGMQMQAAAKE
                     ITRNGGIPFAAFVSDPCDGRSQGTHGMFDSLPYRNDAAIVFRRLIRSLPTRRAVIGVA
                     TCDKGLPATMIALAAMHDLPTILVPGGATLPPTVGEDAGKVQTIGARFANHELSLQEA
                     AELGCRACASPGGGCQFLGTAGTSQVVAEALGLALPHSALAPSGQAVWLEIARQSARA
                     VSELDSRGITTRDILSDKAIENAMVIHAAFGGSTNLLLHIPAIAHAAGCTIPDVEHWT
                     RINRKVPRLVSVLPNGPDYHPTVRAFLAGGVPEVMLHLRDLGLLHLDAMTVTGQTVGE
                     NLEWWQASERRARFRQCLREQDGVEPDDVILPPEKAKAKGLTSTVCFPTGNIAPEGSV
                     IKATAIDPSVVGEDGVYHHTGRVRVFVSEAQAIKAIKREEIVQGDIMVVIGGGPSGTG
                     MEETYQLTSALKHISWGKTVSLITDARFSGVSTGACFGHVSPEALAGGPIGKLRDNDI
                     IEIAVDRLTLTGSVNFIGTADNPLTPEEGARELARRQTHPDLHAHDFLPDDTRLWAAL
                     QSVSGGTWKGCIYDTDKIIEVINAGKKALGI"
     misc_feature    283201..285162
                     /gene="yagF"
                     /locus_tag="b0269"
                     /gene_synonym="ECK0270; JW0262"
                     /note="putative dehydratase; Provisional; Region:
                     PRK08211"
                     /db_xref="CDD:236189"
     gene            285395..286777
                     /gene="yagG"
                     /locus_tag="b0270"
                     /gene_synonym="ECK0271; JW0263"
                     /db_xref="EcoGene:EG13346"
                     /db_xref="GeneID:944947"
     CDS             285395..286777
                     /gene="yagG"
                     /locus_tag="b0270"
                     /gene_synonym="ECK0271; JW0263"
                     /function="Phage or Prophage Related"
                     /note="putative permease"
                     /codon_start=1
                     /transl_table=11
                     /product="CP4-6 prophage; putative sugar transporter"
                     /protein_id="NP_414804.1"
                     /db_xref="GI:16128255"
                     /db_xref="ASAP:ABE-0000929"
                     /db_xref="UniProtKB/Swiss-Prot:P75683"
                     /db_xref="EcoGene:EG13346"
                     /db_xref="GeneID:944947"
                     /translation="MTQLTMKDKIGYGLGDTACGFVWQATMFLLAYFYTDVFGLSAGI
                     MGTLFLVSRVLDAVTDPLMGLLVDRTRTRHGQFRPFLLWGAIPFGIVCVLTFYTPDFS
                     AQGKIIYACVTYILLTLVYTFVNVPYCAMPGVITADPKERHALQSWRFFLAAAGSLAI
                     SGIALPLVSIIGKGDEQVGYFGAMCVLGLSGVVLLYVCFFTTKERYTFEVQPGSSVAK
                     DLKLLLGNSQWRIMCAFKMMATCSNVVRGGATLYFVKYVMDHPELATQFLLYGSLATM
                     FGSLCSSRLLGRFDRVTAFKWIIVAYSLISLLIFVTPAEHIALIFALNILFLFVFNTT
                     TPLQWLMASDVVDYEESRSGRRLDGLVFSTYLFSLKIGLAIGGAVVGWILAYVNYSAS
                     SSVQPVEVLTTIKILFCVVPVVLYAGMFIMLSLYKLTDARVEAISRQLIKHRAAQGEA
                     VPDAATAASH"
     misc_feature    285419..286717
                     /gene="yagG"
                     /locus_tag="b0270"
                     /gene_synonym="ECK0271; JW0263"
                     /note="sugar (Glycoside-Pentoside-Hexuronide) transporter;
                     Region: gph; TIGR00792"
                     /db_xref="CDD:233128"
     misc_feature    285422..286570
                     /gene="yagG"
                     /locus_tag="b0270"
                     /gene_synonym="ECK0271; JW0263"
                     /note="The Major Facilitator Superfamily (MFS) is a large
                     and diverse group of secondary transporters that includes
                     uniporters, symporters, and antiporters. MFS proteins
                     facilitate the transport across cytoplasmic or internal
                     membranes of a variety of...; Region: MFS; cd06174"
                     /db_xref="CDD:119392"
     misc_feature    order(285461..285463,285470..285478,285482..285487,
                     285539..285541,285548..285553,285560..285562,
                     285572..285577,285581..285586,285755..285760,
                     285767..285772,285779..285784,285791..285793,
                     285830..285835,285842..285847,285863..285865,
                     286109..286111,286118..286123,286130..286135,
                     286142..286144,286184..286186,286196..286198,
                     286208..286210,286217..286219,286229..286231,
                     286376..286378,286385..286390,286397..286399,
                     286409..286414,286421..286423,286475..286480,
                     286487..286492,286499..286504,286511..286513)
                     /gene="yagG"
                     /locus_tag="b0270"
                     /gene_synonym="ECK0271; JW0263"
                     /note="putative substrate translocation pore; other site"
                     /db_xref="CDD:119392"
     gene            286789..288399
                     /gene="yagH"
                     /locus_tag="b0271"
                     /gene_synonym="ECK0272; JW0264"
                     /db_xref="EcoGene:EG13347"
                     /db_xref="GeneID:944949"
     CDS             286789..288399
                     /gene="yagH"
                     /locus_tag="b0271"
                     /gene_synonym="ECK0272; JW0264"
                     /function="Phage or Prophage Related"
                     /note="putative beta-xylosidase"
                     /codon_start=1
                     /transl_table=11
                     /product="CP4-6 prophage; putative
                     xylosidase/arabinosidase"
                     /protein_id="NP_414805.1"
                     /db_xref="GI:16128256"
                     /db_xref="ASAP:ABE-0000931"
                     /db_xref="UniProtKB/Swiss-Prot:P77713"
                     /db_xref="EcoGene:EG13347"
                     /db_xref="GeneID:944949"
                     /translation="MEITNPILTGFNPDPSLCRQGEDYYIATSTFEWFPGVRIYHSRD
                     LKNWSLVSTPLDRVSMLDMKGNPDSGGIWAPCLSYADGKFWLLYTDVKIVDSPWKNGR
                     NFLVTAPSIEGPWSEPIPMGNGGFDPSLFHDDDGRKYYIYRPWGPRHHSNPHNTIVLQ
                     AFDPQTGTLSPERKTLFTGTPLCYTEGAHLYRHAGWYYLMAAEGGTSYEHAVVVLRSK
                     NIDGPYELHPDVTMMTSWHLPENPLQKSGHGSLLQTHTGEWYMAYLTSRPLRLPGVPL
                     LASGGRGYCPLGRETGIARIEWRDGWPYVEGGKHAQLTVKGPQVAEQPAAVPGNWRDD
                     FDASSLDPELQTLRIPFDDTLGSLTARPGFLRLYGNDSLNSTFTQSTVARRWQHFAFR
                     AETRMEFSPVHFQQSAGLTCYYNSKNWSYCFVDYEEGQGRTIKVIQLDHNVPSWPLHE
                     QPIPVPEHAESVWLRVDVDTLVYRYSYSFDGETWHTVPVTYEAWKLSDDYIGGRGFFT
                     GAFVGLHCEDISGDGCYADFDYFTYEPV"
     misc_feature    286789..288396
                     /gene="yagH"
                     /locus_tag="b0271"
                     /gene_synonym="ECK0272; JW0264"
                     /note="Beta-xylosidase [Carbohydrate transport and
                     metabolism]; Region: XynB; COG3507"
                     /db_xref="CDD:226038"
     misc_feature    286801..287703
                     /gene="yagH"
                     /locus_tag="b0271"
                     /gene_synonym="ECK0272; JW0264"
                     /note="Glycosyl hydrolase family 43, beta-D-xylosidase;
                     Region: GH43_XYL_1; cd09000"
                     /db_xref="CDD:185741"
     misc_feature    order(286828..286830,286879..286881,287005..287010,
                     287164..287169,287344..287346,287401..287406,
                     287530..287532,287653..287655)
                     /gene="yagH"
                     /locus_tag="b0271"
                     /gene_synonym="ECK0272; JW0264"
                     /note="inhibitor binding site; inhibition site"
                     /db_xref="CDD:185741"
     misc_feature    order(286828..286830,287167..287169,287344..287346)
                     /gene="yagH"
                     /locus_tag="b0271"
                     /gene_synonym="ECK0272; JW0264"
                     /note="active site"
                     /db_xref="CDD:185741"
     misc_feature    <287956..288393
                     /gene="yagH"
                     /locus_tag="b0271"
                     /gene_synonym="ECK0272; JW0264"
                     /note="Protein of unknown function (DUF1349); Region:
                     DUF1349; cl01397"
                     /db_xref="CDD:242478"
     gene            complement(288404..289162)
                     /gene="yagI"
                     /locus_tag="b0272"
                     /gene_synonym="ECK0273; JW0265"
                     /db_xref="EcoGene:EG13349"
                     /db_xref="GeneID:945016"
     CDS             complement(288404..289162)
                     /gene="yagI"
                     /locus_tag="b0272"
                     /gene_synonym="ECK0273; JW0265"
                     /function="Phage or Prophage Related"
                     /GO_function="GO:0016564 - transcription repressor
                     activity"
                     /GO_process="GO:0006350 - transcription"
                     /note="putative regulator"
                     /codon_start=1
                     /transl_table=11
                     /product="CP4-6 prophage; putative DNA-binding
                     transcriptional regulator"
                     /protein_id="NP_414806.1"
                     /db_xref="GI:16128257"
                     /db_xref="ASAP:ABE-0000933"
                     /db_xref="UniProtKB/Swiss-Prot:P77300"
                     /db_xref="EcoGene:EG13349"
                     /db_xref="GeneID:945016"
                     /translation="MPIIQSVERALQILDLFNEQATELKITDISKLMGLSKSTLHSLL
                     KTLQLHGYIDQNPENGKYRLGMKLVERGHFVVGSIDIRQKAKGWLTELSRRTGQTTHL
                     GILDGREGVYIEKIEGKLAAIAYSRIGRRLPVHATAIGKVLIAWLGEAELNALLEGYQ
                     YTTFTPATLASREALMSALAQTREQGYALDSEENEQGVRCVAVPVWNHESRVIAALSL
                     STLTSRVDDAELANFREQLQQAGLALSRALGYPA"
     misc_feature    complement(288881..289153)
                     /gene="yagI"
                     /locus_tag="b0272"
                     /gene_synonym="ECK0273; JW0265"
                     /note="helix_turn_helix isocitrate lyase regulation;
                     Region: HTH_ICLR; smart00346"
                     /db_xref="CDD:214629"
     misc_feature    complement(288413..289150)
                     /gene="yagI"
                     /locus_tag="b0272"
                     /gene_synonym="ECK0273; JW0265"
                     /note="Transcriptional regulator [Transcription]; Region:
                     IclR; COG1414"
                     /db_xref="CDD:224332"
     misc_feature    complement(288422..288793)
                     /gene="yagI"
                     /locus_tag="b0272"
                     /gene_synonym="ECK0273; JW0265"
                     /note="Bacterial transcriptional regulator; Region: IclR;
                     pfam01614"
                     /db_xref="CDD:250746"
     gene            complement(289301..290305)
                     /gene="argF"
                     /locus_tag="b0273"
                     /gene_synonym="Arg5; argD; ECK0274; JW0266"
                     /db_xref="EcoGene:EG10067"
                     /db_xref="GeneID:944844"
     CDS             complement(289301..290305)
                     /gene="argF"
                     /locus_tag="b0273"
                     /gene_synonym="Arg5; argD; ECK0274; JW0266"
                     /EC_number="2.1.3.3"
                     /function="enzyme; Amino acid biosynthesis: Arginine;
                     Phage or Prophage Related"
                     /GO_component="GO:0005737 - cytoplasm"
                     /GO_process="GO:0006526 - arginine biosynthetic process"
                     /note="ornithine carbamoyltransferase 2, chain F"
                     /codon_start=1
                     /transl_table=11
                     /product="ornithine carbamoyltransferase 2, chain F; CP4-6
                     prophage"
                     /protein_id="NP_414807.1"
                     /db_xref="GI:16128258"
                     /db_xref="ASAP:ABE-0000939"
                     /db_xref="UniProtKB/Swiss-Prot:P06960"
                     /db_xref="EcoGene:EG10067"
                     /db_xref="GeneID:944844"
                     /translation="MSDLYKKHFLKLLDFTPAQFTSLLTLAAQLKADKKNGKEVQKLT
                     GKNIALIFEKDSTRTRCSFEVAAFDQGARVTYLGPSGSQIGHKESIKDTARVLGRMYD
                     GIQYRGHGQEVVETLAQYAGVPVWNGLTNEFHPTQLLADLMTMQEHLPGKAFNEMTLV
                     YAGDARNNMGNSMLEAAALTGLDLRLLAPKACWPEESLVAECSALAEKHGGKITLTED
                     VAAGVKGADFIYTDVWVSMGEAKEKWAERIALLRGYQVNAQMMALTDNPNVKFLHCLP
                     AFHDDQTTLGKQMAKEFDLHGGMEVTDEVFESAASIVFDQAENRMHTIKAVMMATLGE
                     "
     misc_feature    complement(289310..290305)
                     /gene="argF"
                     /locus_tag="b0273"
                     /gene_synonym="Arg5; argD; ECK0274; JW0266"
                     /note="ornithine carbamoyltransferase subunit I;
                     Provisional; Region: PRK03515"
                     /db_xref="CDD:179587"
     misc_feature    complement(289862..290287)
                     /gene="argF"
                     /locus_tag="b0273"
                     /gene_synonym="Arg5; argD; ECK0274; JW0266"
                     /note="Aspartate/ornithine carbamoyltransferase,
                     carbamoyl-P binding domain; Region: OTCace_N; pfam02729"
                     /db_xref="CDD:251498"
     misc_feature    complement(289322..289843)
                     /gene="argF"
                     /locus_tag="b0273"
                     /gene_synonym="Arg5; argD; ECK0274; JW0266"
                     /note="Aspartate/ornithine carbamoyltransferase, Asp/Orn
                     binding domain; Region: OTCace; pfam00185"
                     /db_xref="CDD:249663"
     gene            290429..290633
                     /gene="ykgS"
                     /locus_tag="b4688"
                     /gene_synonym="ECK4504"
                     /pseudo
                     /db_xref="EcoGene:EG14492"
                     /db_xref="GeneID:7751632"
     CDS             290429..290633
                     /gene="ykgS"
                     /locus_tag="b4688"
                     /gene_synonym="ECK4504"
                     /note="pseudogene"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /db_xref="EcoGene:EG14492"
                     /db_xref="GeneID:7751632"
     mobile_element  complement(290634..291401)
                     /mobile_element_type="insertion sequence:IS1C"
     gene            complement(290649..291152)
                     /gene="insB1"
                     /locus_tag="b0274"
                     /gene_synonym="ECK0022"
                     /db_xref="EcoGene:EG40002"
                     /db_xref="GeneID:944950"
     CDS             complement(290649..291152)
                     /gene="insB1"
                     /locus_tag="b0274"
                     /gene_synonym="ECK0022"
                     /function="IS, phage, Tn; Transposon-related functions;
                     extrachromosomal; transposon related"
                     /codon_start=1
                     /transl_table=11
                     /product="IS1 transposase B"
                     /protein_id="NP_414808.1"
                     /db_xref="GI:16128259"
                     /db_xref="ASAP:ABE-0000948"
                     /db_xref="UniProtKB/Swiss-Prot:P0CF27"
                     /db_xref="EcoGene:EG40002"
                     /db_xref="GeneID:944950"
                     /translation="MPGNRPHYGRWPQHDFPPFKKLRPQSVTSRIQPGSDVIVCAEMD
                     EQWGYVGAKSRQRWLFYAYDRLRKTVVAHVFGERTMATLGRLMSLLSPFDVVIWMTDG
                     WPLYESRLKGKLHVISKRYTQRIERHNLNLRQHLARLGRKSLSFSKSVEQHDKVIGHY
                     LNIKHYQ"
     misc_feature    complement(290652..291041)
                     /gene="insB1"
                     /locus_tag="b0274"
                     /gene_synonym="ECK0022"
                     /note="IS1 transposase; Region: DDE_Tnp_IS1; pfam03400"
                     /db_xref="CDD:112225"
     gene            complement(291071..291346)
                     /gene="insA"
                     /locus_tag="b0275"
                     /gene_synonym="ECK4523"
                     /note="insA3"
                     /db_xref="EcoGene:EG40001"
                     /db_xref="GeneID:944951"
     CDS             complement(291071..291346)
                     /gene="insA"
                     /locus_tag="b0275"
                     /gene_synonym="ECK4523"
                     /function="IS, phage, Tn; Transposon-related functions;
                     extrachromosomal; transposon related"
                     /codon_start=1
                     /transl_table=11
                     /product="IS1 repressor TnpA"
                     /protein_id="NP_414809.1"
                     /db_xref="GI:16128260"
                     /db_xref="ASAP:ABE-0000951"
                     /db_xref="UniProtKB/Swiss-Prot:P0CF09"
                     /db_xref="EcoGene:EG40001"
                     /db_xref="GeneID:944951"
                     /translation="MASVSISCPSCSATDGVVRNGKSTAGHQRYLCSHCRKTWQLQFT
                     YTASQPGTHQKIIDMAMNGVGCRATARIMGVGLNTIFRHLKNSGRSR"
     misc_feature    complement(291074..291346)
                     /gene="insA"
                     /locus_tag="b0275"
                     /gene_synonym="ECK4523"
                     /note="Transposase and inactivated derivatives [DNA
                     replication, recombination, and repair]; Region: COG3677"
                     /db_xref="CDD:226202"
     misc_feature    complement(291239..291346)
                     /gene="insA"
                     /locus_tag="b0275"
                     /gene_synonym="ECK4523"
                     /note="InsA N-terminal domain; Region: Zn_Tnp_IS1;
                     pfam03811"
                     /db_xref="CDD:190760"
     misc_feature    complement(291083..291220)
                     /gene="insA"
                     /locus_tag="b0275"
                     /gene_synonym="ECK4523"
                     /note="InsA C-terminal domain; Region: HTH_Tnp_IS1;
                     pfam12759"
                     /db_xref="CDD:257276"
     gene            291404..292231
                     /gene="yagJ"
                     /locus_tag="b0276"
                     /gene_synonym="ECK0275; JW0270"
                     /pseudo
                     /db_xref="EcoGene:EG13549"
                     /db_xref="GeneID:949094"
     CDS             291404..292231
                     /gene="yagJ"
                     /locus_tag="b0276"
                     /gene_synonym="ECK0275; JW0270"
                     /note="CP4-6 prophage; uncharacterized protein;Phage or
                     Prophage Related"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /db_xref="ASAP:ABE-0000963"
                     /db_xref="UniProtKB/Swiss-Prot:P77169"
                     /db_xref="EcoGene:EG13549"
                     /db_xref="GeneID:949094"
     gene            complement(292322..292948)
                     /gene="yagK"
                     /locus_tag="b0277"
                     /gene_synonym="ECK0276; JW0271"
                     /db_xref="EcoGene:EG13550"
                     /db_xref="GeneID:945847"
     CDS             complement(292322..292948)
                     /gene="yagK"
                     /locus_tag="b0277"
                     /gene_synonym="ECK0276; JW0271"
                     /function="Phage or Prophage Related"
                     /codon_start=1
                     /transl_table=11
                     /product="CP4-6 prophage; conserved protein"
                     /protein_id="NP_414811.1"
                     /db_xref="GI:16128262"
                     /db_xref="ASAP:ABE-0000965"
                     /db_xref="UniProtKB/Swiss-Prot:P77657"
                     /db_xref="EcoGene:EG13550"
                     /db_xref="GeneID:945847"
                     /translation="MKTYQGTHGVHILEYQSKINKLLCYLTNRYPRLIAVRVDLHYPK
                     IVDNGDNICCFPNLEPGVISRMRESLRAKLEADRTRKVREDKRIYRCPLFIIWAKEYS
                     ESGKCHYHICLLFNKDAYYHLGDYDQDDNLRGMITGAWYSALRLERDDHPGLVHFPEN
                     CKYVLDTNSTDFQQNYQALLTRLDYLTKVESKVFGEGDRNFGCSQIEL"
     misc_feature    complement(292334..292897)
                     /gene="yagK"
                     /locus_tag="b0277"
                     /gene_synonym="ECK0276; JW0271"
                     /note="Protein of unknown function (DUF3296); Region:
                     DUF3296; pfam11726"
                     /db_xref="CDD:256576"
     gene            complement(293220..293918)
                     /gene="yagL"
                     /locus_tag="b0278"
                     /gene_synonym="ECK0277; JW0272"
                     /db_xref="EcoGene:EG13551"
                     /db_xref="GeneID:945845"
     CDS             complement(293220..293918)
                     /gene="yagL"
                     /locus_tag="b0278"
                     /gene_synonym="ECK0277; JW0272"
                     /function="Phage or Prophage Related"
                     /note="DNA-binding protein"
                     /codon_start=1
                     /transl_table=11
                     /product="CP4-6 prophage; DNA-binding protein"
                     /protein_id="NP_414812.1"
                     /db_xref="GI:16128263"
                     /db_xref="ASAP:ABE-0000970"
                     /db_xref="UniProtKB/Swiss-Prot:P77607"
                     /db_xref="EcoGene:EG13551"
                     /db_xref="GeneID:945845"
                     /translation="MRGKILLYQLKYRWQSLSIFGCFLCKMTLFRYQKIIYDTGVHQM
                     RSFFYTICSSEQQESITDHHSLAEICQKFNILPEHVVIEQVDIKEVVSEQRLLRQLIH
                     HEMNRQDTLVIPDLSCLGRTVEDLQNILFFCLQKEMFIYSYHPASRIEPSAESCLSFL
                     IARQDTIDIHNLKSTKSRYRHVKKKLGRKEGSKYRRDITILKKGGFTQAEIAKKLSIS
                     LSTVKRHWNNGIIG"
     misc_feature    complement(293226..293915)
                     /gene="yagL"
                     /locus_tag="b0278"
                     /gene_synonym="ECK0277; JW0272"
                     /note="Site-specific recombinases, DNA invertase Pin
                     homologs [DNA replication, recombination, and repair];
                     Region: PinR; COG1961"
                     /db_xref="CDD:224872"
     misc_feature    complement(<293244..293336)
                     /gene="yagL"
                     /locus_tag="b0278"
                     /gene_synonym="ECK0277; JW0272"
                     /note="C-terminal DNA-binding domain of LuxR-like
                     proteins. This domain contains a helix-turn-helix motif
                     and binds DNA. Proteins belonging to this group are
                     response regulators; some act as transcriptional
                     activators, others as transcriptional repressors. Many...;
                     Region: LuxR_C_like; cl17315"
                     /db_xref="CDD:266624"
     gene            complement(293945..294799)
                     /gene="yagM"
                     /locus_tag="b0279"
                     /gene_synonym="ECK0278; JW0273"
                     /db_xref="EcoGene:EG13552"
                     /db_xref="GeneID:944959"
     CDS             complement(293945..294799)
                     /gene="yagM"
                     /locus_tag="b0279"
                     /gene_synonym="ECK0278; JW0273"
                     /function="Phage or Prophage Related"
                     /codon_start=1
                     /transl_table=11
                     /product="CP4-6 prophage; uncharacterized protein"
                     /protein_id="NP_414813.1"
                     /db_xref="GI:16128264"
                     /db_xref="ASAP:ABE-0000972"
                     /db_xref="UniProtKB/Swiss-Prot:P71296"
                     /db_xref="EcoGene:EG13552"
                     /db_xref="GeneID:944959"
                     /translation="MSNSVTNFEMSSVLPGKKPCQGKNNESQVVQTTPIKKHSVTFKN
                     QSSLGVIDHYARLTNKSHSSVIAEVVDLAIPILEKCNRHNWSINEIKNDLLKFSIKES
                     INRSRGKTEVTLEEYCSLIWKTNIMSPLKIPIADYFQLNANDEFMGKDEKTVIRERLS
                     SLRENYDMEKAIYIYNQRHFDVKHQSVSGYSNIILIHRTTFEGYYFDAGQALLLSTSQ
                     LIIFGINEVLRRKGIVMPYPVVCWIDIYHVNEMVVMLPVLRKTDVSNRVNVPDDIIIN
                     PYSQESRT"
     gene            complement(295139..295579)
                     /gene="yagN"
                     /locus_tag="b0280"
                     /gene_synonym="ECK0279; JW0274"
                     /db_xref="EcoGene:EG13553"
                     /db_xref="GeneID:945349"
     CDS             complement(295139..295579)
                     /gene="yagN"
                     /locus_tag="b0280"
                     /gene_synonym="ECK0279; JW0274"
                     /function="Phage or Prophage Related"
                     /codon_start=1
                     /transl_table=11
                     /product="CP4-6 prophage; uncharacterized protein"
                     /protein_id="NP_414814.1"
                     /db_xref="GI:16128265"
                     /db_xref="ASAP:ABE-0000976"
                     /db_xref="UniProtKB/Swiss-Prot:P71297"
                     /db_xref="EcoGene:EG13553"
                     /db_xref="GeneID:945349"
                     /translation="MATPATVSIEPTLAAIRARWCINSSKTTQSFNDPASMEEVVEYL
                     KGTYSALRKSVACAKLKILHLKQRMQNATNFLARLMSCKNQASRSHHSTAKSAKSALS
                     SDSGDGSDPDPEPETFPSAFITTPTNSIMLKAFFANISITEVAK"
     gene            complement(295696..297096)
                     /gene="intF"
                     /locus_tag="b0281"
                     /gene_synonym="ECK0280; JW0275; yagO"
                     /db_xref="EcoGene:EG13554"
                     /db_xref="GeneID:947351"
     CDS             complement(295696..297096)
                     /gene="intF"
                     /locus_tag="b0281"
                     /gene_synonym="ECK0280; JW0275; yagO"
                     /function="Phage or Prophage Related"
                     /note="putative phage integrase"
                     /codon_start=1
                     /transl_table=11
                     /product="CP4-6 prophage; putative phage integrase"
                     /protein_id="NP_414815.1"
                     /db_xref="GI:16128266"
                     /db_xref="ASAP:ABE-0000979"
                     /db_xref="UniProtKB/Swiss-Prot:P71298"
                     /db_xref="EcoGene:EG13554"
                     /db_xref="GeneID:947351"
                     /translation="MFIPSIYLHQQLHYCKTAILNWSRKMALSRQKFTFERLRRFTLP
                     EGKKQTFLWDADVTTLACRATSGAKAFVFQSVYAGKTLRMTIGNINDWKIDDARAEAR
                     RLQTLIDTGIDPRIAKAVKIAEAESLQAESRKTKVTFSVAWEDYLQELRTGISAKTKR
                     PYSTRYIADHINLSSRGGESKKRGQGPTSAGPLASLLNLPLSELTPDYIAAWLSTERQ
                     NRPTVTAHAYRLLRAFIKWSNYQKKYQGIIPGDLAQDYNVRKMVPVSASKADDCLQKE
                     QLKSWFSAVRSLNNPIASAYLQVLLLTGARREEIASLRWSDVDFKWSSMRIKDKIEGE
                     RIIPLTPYVSELLNVLAQSPNSDVNKEGWVFRSNSKSGKIIEPRSAHNRALVLAELPH
                     ISLHGLRRSFGTLAEWVEVPTGIVAQIMGHKPSALAEKHYRRRPLDLLRKWHEKIETW
                     ILNEAGITIKNNVDMR"
     misc_feature    complement(295762..296904)
                     /gene="intF"
                     /locus_tag="b0281"
                     /gene_synonym="ECK0280; JW0275; yagO"
                     /note="DNA breaking-rejoining enzymes, C-terminal
                     catalytic domain. The DNA breaking-rejoining enzyme
                     superfamily includes type IB topoisomerases and tyrosine
                     recombinases that share the same fold in their catalytic
                     domain containing six conserved active site...; Region:
                     DNA_BRE_C; cl00213"
                     /db_xref="CDD:260266"
     misc_feature    complement(order(295801..295803,295909..295917,
                     296176..296181))
                     /gene="intF"
                     /locus_tag="b0281"
                     /gene_synonym="ECK0280; JW0275; yagO"
                     /note="DNA binding site [nucleotide binding]"
                     /db_xref="CDD:238231"
     misc_feature    complement(order(295801..295803,295831..295833,
                     295900..295902,295909..295911,296179..296181))
                     /gene="intF"
                     /locus_tag="b0281"
                     /gene_synonym="ECK0280; JW0275; yagO"
                     /note="active site"
                     /db_xref="CDD:238231"
     misc_feature    complement(order(295801..295803,295831..295833,
                     295900..295902,295909..295911,296179..296181))
                     /gene="intF"
                     /locus_tag="b0281"
                     /gene_synonym="ECK0280; JW0275; yagO"
                     /note="Int/Topo IB signature motif; other site"
                     /db_xref="CDD:238231"
     gene            297206..297254
                     /gene="ptwF"
                     /locus_tag="b4629"
                     /gene_synonym="ECK4462"
                     /pseudo
                     /db_xref="EcoGene:EG31171"
                     /db_xref="GeneID:5625555"
     tRNA            297206..297254
                     /gene="ptwF"
                     /locus_tag="b4629"
                     /gene_synonym="ECK4462"
                     /product="tRNA-OTHER"
                     /pseudo
                     /db_xref="EcoGene:EG31171"
                     /db_xref="GeneID:5625555"
     gene            complement(297381..297719)
                     /gene="yagP"
                     /locus_tag="b4694"
                     /gene_synonym="ECK0281; JW0276"
                     /pseudo
                     /db_xref="EcoGene:EG13555"
                     /db_xref="GeneID:7751633"
     CDS             complement(297381..297719)
                     /gene="yagP"
                     /locus_tag="b4694"
                     /gene_synonym="ECK0281; JW0276"
                     /GO_process="GO:0006355 - regulation of transcription,
                     DNA-dependent"
                     /note="pseudogene, LysR family, fragment;putative
                     regulator; Not classified;
                     putative transcriptional regulator LYSR-type"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /db_xref="ASAP:ABE-0000982"
                     /db_xref="UniProtKB/Swiss-Prot:P75684"
                     /db_xref="EcoGene:EG13555"
                     /db_xref="GeneID:7751633"
     gene            complement(297714..297791)
                     /gene="ykgT"
                     /locus_tag="b4695"
                     /gene_synonym="ECK4508; yagP"
                     /pseudo
                     /db_xref="EcoGene:EG14496"
                     /db_xref="GeneID:7751634"
     CDS             complement(297714..297791)
                     /gene="ykgT"
                     /locus_tag="b4695"
                     /gene_synonym="ECK4508; yagP"
                     /note="pseudogene, MobA-related"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /db_xref="EcoGene:EG14496"
                     /db_xref="GeneID:7751634"
     gene            complement(297770..298726)
                     /gene="paoD"
                     /locus_tag="b0283"
                     /gene_synonym="ECK0282; JW0277; yagQ"
                     /db_xref="EcoGene:EG13556"
                     /db_xref="GeneID:945010"
     CDS             complement(297770..298726)
                     /gene="paoD"
                     /locus_tag="b0283"
                     /gene_synonym="ECK0282; JW0277; yagQ"
                     /codon_start=1
                     /transl_table=11
                     /product="moco insertion factor for PaoABC aldehyde
                     oxidoreductase"
                     /protein_id="NP_414817.1"
                     /db_xref="GI:16128268"
                     /db_xref="ASAP:ABE-0000984"
                     /db_xref="UniProtKB/Swiss-Prot:P77183"
                     /db_xref="EcoGene:EG13556"
                     /db_xref="GeneID:945010"
                     /translation="MSYPLFDKDEHWHKPEQAFLTDDHRTILRFAVEALMSGKGAVLV
                     TLVEIRGGAARPLGAQMVVREDGRYCGFVSGGCVEAAAAFEALEMMGSGRDREIRYGE
                     GSPWFDIVLPCGGGITLTLHKLRSAQPLLAVLNRLEQRKPVGLRYDPQAQSLVCLPTQ
                     TRTGWNLNGFEVGFRPCVRLMIYGRSLEAQATASLAAATGYDSHIFDLFPASASAQID
                     TDTAVILLCHDLNRELPVLQAAREAKPFYLGALGSYRTHTLRLQKLHELGWSREETTQ
                     IRAPVGIFPKARDAHTLALSVLAEVASVRLHQEEDSCLPPSS"
     misc_feature    complement(297773..298654)
                     /gene="paoD"
                     /locus_tag="b0283"
                     /gene_synonym="ECK0282; JW0277; yagQ"
                     /note="Xanthine and CO dehydrogenases maturation factor,
                     XdhC/CoxF family [Posttranslational modification, protein
                     turnover, chaperones]; Region: XdhC; COG1975"
                     /db_xref="CDD:224886"
     misc_feature    complement(298424..298633)
                     /gene="paoD"
                     /locus_tag="b0283"
                     /gene_synonym="ECK0282; JW0277; yagQ"
                     /note="XdhC and CoxI family; Region: XdhC_CoxI; pfam02625"
                     /db_xref="CDD:251428"
     misc_feature    complement(297824..298132)
                     /gene="paoD"
                     /locus_tag="b0283"
                     /gene_synonym="ECK0282; JW0277; yagQ"
                     /note="XdhC Rossmann domain; Region: XdhC_C; pfam13478"
                     /db_xref="CDD:257802"
     gene            complement(298736..300934)
                     /gene="paoC"
                     /locus_tag="b0284"
                     /gene_synonym="ECK0283; hsm; JW0278; yagR"
                     /db_xref="EcoGene:EG13557"
                     /db_xref="GeneID:944961"
     CDS             complement(298736..300934)
                     /gene="paoC"
                     /locus_tag="b0284"
                     /gene_synonym="ECK0283; hsm; JW0278; yagR"
                     /function="enzyme; Not classified"
                     /codon_start=1
                     /transl_table=11
                     /product="PaoABC aldehyde oxidoreductase, Moco-containing
                     subunit"
                     /protein_id="NP_414818.1"
                     /db_xref="GI:16128269"
                     /db_xref="ASAP:ABE-0000988"
                     /db_xref="UniProtKB/Swiss-Prot:P77489"
                     /db_xref="EcoGene:EG13557"
                     /db_xref="GeneID:944961"
                     /translation="MKFDKPAGENPIDQLKVVGRPHDRIDGPLKTTGTARYAYEWHEE
                     APNAAYGYIVGSAIAKGRLTALDTDAAQKAPGVLAVITASNAGALGKGDKNTARLLGG
                     PTIEHYHQAIALVVAETFEQARAAASLVQAHYRRNKGAYSLADEKQAVNQPPEDTPDK
                     NVGDFDGAFTSAAVKIDATYTTPDQSHMAMEPHASMAVWDGNKLTLWTSNQMIDWCRT
                     DLAKTLKVPVENVRIISPYIGGGFGGKLFLRSDALLAALAARAVKRPVKVMLPRPSIP
                     NNTTHRPATLQHLRIGADQSGKITAISHESWSGNLPGGTPETAVQQSELLYAGANRHT
                     GLRLATLDLPEGNAMRAPGEAPGLMALEIAIDELAEKAGIDPVEFRILNDTQVDPADP
                     TRCFSRRQLIECLRTGADKFGWKQRNATPGQVRDGEWLVGHGVAAGFRNNLLEKSGAR
                     VHLEQNGTVTVETDMTDIGTGSYTILAQTAAEMLGVPLEQVAVHLGDSSFPVSAGSGG
                     QWGANTSTSGVYAACMKLREMIASAVGFDPEQSQFADGKITNGTRSATLHEATAGGRL
                     TAEESIEFGTLSKEYQQSTFAGHFVEVGVHSATGEVRVRRMLAVCAAGRILNPKTARS
                     QVIGAMTMGMGAALMEELAVDDRLGYFVNHDMAGYEVPVHADIPKQEVIFLDDTDPIS
                     SPMKAKGVGELGLCGVSAAIANAVYNATGIRVRDYPITLDKLLDKLPDVV"
     misc_feature    complement(298745..300898)
                     /gene="paoC"
                     /locus_tag="b0284"
                     /gene_synonym="ECK0283; hsm; JW0278; yagR"
                     /note="Aerobic-type carbon monoxide dehydrogenase, large
                     subunit CoxL/CutL homologs [Energy production and
                     conversion]; Region: CoxL; COG1529"
                     /db_xref="CDD:224446"
     misc_feature    complement(300521..300835)
                     /gene="paoC"
                     /locus_tag="b0284"
                     /gene_synonym="ECK0283; hsm; JW0278; yagR"
                     /note="Aldehyde oxidase and xanthine dehydrogenase, a/b
                     hammerhead domain; Region: Ald_Xan_dh_C; pfam01315"
                     /db_xref="CDD:250528"
     misc_feature    complement(298931..300493)
                     /gene="paoC"
                     /locus_tag="b0284"
                     /gene_synonym="ECK0283; hsm; JW0278; yagR"
                     /note="Molybdopterin-binding domain of aldehyde
                     dehydrogenase; Region: Ald_Xan_dh_C2; pfam02738"
                     /db_xref="CDD:251506"
     gene            complement(300931..301887)
                     /gene="paoB"
                     /locus_tag="b0285"
                     /gene_synonym="ECK0284; JW0279; yagS"
                     /db_xref="EcoGene:EG13558"
                     /db_xref="GeneID:945710"
     CDS             complement(300931..301887)
                     /gene="paoB"
                     /locus_tag="b0285"
                     /gene_synonym="ECK0284; JW0279; yagS"
                     /function="enzyme; Not classified"
                     /codon_start=1
                     /transl_table=11
                     /product="PaoABC aldehyde oxidoreductase, FAD-containing
                     subunit"
                     /protein_id="NP_414819.1"
                     /db_xref="GI:16128270"
                     /db_xref="ASAP:ABE-0000990"
                     /db_xref="UniProtKB/Swiss-Prot:P77324"
                     /db_xref="EcoGene:EG13558"
                     /db_xref="GeneID:945710"
                     /translation="MKAFTYERVNTPAEAALSAQRVPGAKFIAGGTNLLDLMKLEIET
                     PTHLIDVNGLGLDKIEVTDAGGLRIGALVRNTDLAAHERVRRDYAVLSRALLAGASGQ
                     LRNQATTAGNLLQRTRCPYFYDTNQPCNKRLPGSGCAALEGFSRQHAVVGVSEACIAT
                     HPSDMAVAMRLLDAVVETITPEGKTRSITLADFYHPPGKTPHIETALLPGELIVAVTL
                     PPPLGGKHIYRKVRDRASYAFALVSVAAIIQPDGSGRVALGGVAHKPWRIEAADAQLS
                     QGAQAVYDTLFASAHPTAENTFKLLLAKRTLASVLAEARAQA"
     misc_feature    complement(300934..301887)
                     /gene="paoB"
                     /locus_tag="b0285"
                     /gene_synonym="ECK0284; JW0279; yagS"
                     /note="Aerobic-type carbon monoxide dehydrogenase, middle
                     subunit CoxM/CutM homologs [Energy production and
                     conversion]; Region: CoxM; COG1319"
                     /db_xref="CDD:224238"
     misc_feature    complement(301225..301884)
                     /gene="paoB"
                     /locus_tag="b0285"
                     /gene_synonym="ECK0284; JW0279; yagS"
                     /note="FAD binding domain in molybdopterin dehydrogenase;
                     Region: FAD_binding_5; pfam00941"
                     /db_xref="CDD:250245"
     misc_feature    complement(300946..301206)
                     /gene="paoB"
                     /locus_tag="b0285"
                     /gene_synonym="ECK0284; JW0279; yagS"
                     /note="CO dehydrogenase flavoprotein C-terminal domain;
                     Region: CO_deh_flav_C; smart01092"
                     /db_xref="CDD:215021"
     gene            complement(301884..302573)
                     /gene="paoA"
                     /locus_tag="b0286"
                     /gene_synonym="ECK0285; JW0280; yagT"
                     /db_xref="EcoGene:EG13559"
                     /db_xref="GeneID:945330"
     CDS             complement(301884..302573)
                     /gene="paoA"
                     /locus_tag="b0286"
                     /gene_synonym="ECK0285; JW0280; yagT"
                     /function="enzyme; Not classified"
                     /note="putative xanthine dehydrogenase"
                     /codon_start=1
                     /transl_table=11
                     /product="PaoABC aldehyde oxidoreductase, 2Fe-2S subunit"
                     /protein_id="NP_414820.1"
                     /db_xref="GI:16128271"
                     /db_xref="ASAP:ABE-0000992"
                     /db_xref="UniProtKB/Swiss-Prot:P77165"
                     /db_xref="EcoGene:EG13559"
                     /db_xref="GeneID:945330"
                     /translation="MSNQGEYPEDNRVGKHEPHDLSLTRRDLIKVSAATAATAVVYPH
                     STLAASVPAATPAPEIMPLTLKVNGKTEQLEVDTRTTLLDTLRENLHLIGTKKGCDHG
                     QCGACTVLVNGRRLNACLTLAVMHQGAEITTIEGLGSPDNLHPMQAAFIKHDGFQCGY
                     CTSGQICSSVAVLKEIQDGIPSHVTVDLVSAPETTADEIRERMSGNICRCGAYANILA
                     AIEDAAGEIKS"
     misc_feature    complement(301890..302540)
                     /gene="paoA"
                     /locus_tag="b0286"
                     /gene_synonym="ECK0285; JW0280; yagT"
                     /note="aldehyde oxidoreductase 2Fe-2S subunit;
                     Provisional; Region: PRK11433"
                     /db_xref="CDD:236910"
     misc_feature    complement(<302238..302387)
                     /gene="paoA"
                     /locus_tag="b0286"
                     /gene_synonym="ECK0285; JW0280; yagT"
                     /note="2Fe-2S iron-sulfur cluster binding domain.
                     Iron-sulfur proteins play an important role in electron
                     transfer processes and in various enzymatic reactions. The
                     family includes plant and algal ferredoxins, which act as
                     electron carriers in photosynthesis...; Region: fer2;
                     cd00207"
                     /db_xref="CDD:238126"
     misc_feature    complement(order(302253..302264,302268..302270,
                     302277..302279,302286..302291))
                     /gene="paoA"
                     /locus_tag="b0286"
                     /gene_synonym="ECK0285; JW0280; yagT"
                     /note="catalytic loop [active]"
                     /db_xref="CDD:238126"
     misc_feature    complement(order(302253..302255,302262..302264,
                     302277..302279))
                     /gene="paoA"
                     /locus_tag="b0286"
                     /gene_synonym="ECK0285; JW0280; yagT"
                     /note="iron binding site [ion binding]; other site"
                     /db_xref="CDD:238126"
     misc_feature    complement(301908..302177)
                     /gene="paoA"
                     /locus_tag="b0286"
                     /gene_synonym="ECK0285; JW0280; yagT"
                     /note="[2Fe-2S] binding domain; Region: Fer2_2; pfam01799"
                     /db_xref="CDD:250876"
     gene            302991..303605
                     /gene="yagU"
                     /locus_tag="b0287"
                     /gene_synonym="ECK0286; JW0281"
                     /db_xref="EcoGene:EG13560"
                     /db_xref="GeneID:945677"
     CDS             302991..303605
                     /gene="yagU"
                     /locus_tag="b0287"
                     /gene_synonym="ECK0286; JW0281"
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1440 family inner membrane acid resistance
                     protein"
                     /protein_id="NP_414821.1"
                     /db_xref="GI:16128272"
                     /db_xref="ASAP:ABE-0000995"
                     /db_xref="UniProtKB/Swiss-Prot:P0AAA1"
                     /db_xref="EcoGene:EG13560"
                     /db_xref="GeneID:945677"
                     /translation="MNIFEQTPPNRRRYGLAAFIGLIAGVVSAFVKWGAEVPLPPRSP
                     VDMFNAACGPESLIRAAGQIDCSRNFLNPPYIFLRDWLGLTDPNAAVYTFAGHVFNWV
                     GVTHIIFSIVFAVGYCVVAEVFPKIKLWQGLLAGALAQLFVHMISFPLMGLTPPLFDL
                     PWYENVSEIFGHLVWFWSIEIIRRDLRNRITHEPDPEIPLGSNR"
     misc_feature    302997..303590
                     /gene="yagU"
                     /locus_tag="b0287"
                     /gene_synonym="ECK0286; JW0281"
                     /note="Predicted periplasmic/secreted protein [Function
                     unknown]; Region: COG3477"
                     /db_xref="CDD:226008"
     gene            complement(303853..304182)
                     /gene="ykgJ"
                     /locus_tag="b0288"
                     /gene_synonym="ECK0287; JW0282"
                     /db_xref="EcoGene:EG14323"
                     /db_xref="GeneID:945905"
     CDS             complement(303853..304182)
                     /gene="ykgJ"
                     /locus_tag="b0288"
                     /gene_synonym="ECK0287; JW0282"
                     /function="putative carrier; Not classified"
                     /GO_function="GO:0009055 - electron carrier activity"
                     /note="putative ferredoxin"
                     /codon_start=1
                     /transl_table=11
                     /product="UPF0153 cysteine cluster protein"
                     /protein_id="NP_414822.1"
                     /db_xref="GI:16128273"
                     /db_xref="ASAP:ABE-0000997"
                     /db_xref="UniProtKB/Swiss-Prot:P0AAL9"
                     /db_xref="EcoGene:EG14323"
                     /db_xref="GeneID:945905"
                     /translation="MSNLNPCMTCGACCAFFRVSFYWAEADDAGGTIPARLTEQISPF
                     HRCMSGTNQKNPRCIALAGTPGKNACCTIYKNRSSTCREFAMSGENGVVNEACNRARA
                     KYGLTPL"
     misc_feature    complement(303856..304182)
                     /gene="ykgJ"
                     /locus_tag="b0288"
                     /gene_synonym="ECK0287; JW0282"
                     /note="Predicted Fe-S-cluster oxidoreductase [General
                     function prediction only]; Region: COG0727"
                     /db_xref="CDD:223799"
     gene            complement(304495..305205)
                     /gene="ecpE"
                     /locus_tag="b0289"
                     /gene_synonym="ECK0288; JW5030; matF; yagV"
                     /db_xref="EcoGene:EG13561"
                     /db_xref="GeneID:946631"
     CDS             complement(304495..305205)
                     /gene="ecpE"
                     /locus_tag="b0289"
                     /gene_synonym="ECK0288; JW5030; matF; yagV"
                     /function="factor; Surface structures"
                     /codon_start=1
                     /transl_table=11
                     /product="ECP production pilus chaperone"
                     /protein_id="NP_414823.2"
                     /db_xref="GI:90111108"
                     /db_xref="ASAP:ABE-0001000"
                     /db_xref="UniProtKB/Swiss-Prot:P77263"
                     /db_xref="EcoGene:EG13561"
                     /db_xref="GeneID:946631"
                     /translation="MFRRRGVTLTKALLTAVCMLAAPLTQAISVGNLTFSLPSETDFV
                     SKRVVNNNKSARIYRIAISAIDSPGSSELRTRPVDGELLFAPRQLALQAGESEYFKFY
                     YHGPRDNRERYYRVSFREVPTRNHTRRSPTGGVVSTEPVVVMDTILVVRPRQVQFKWS
                     FDKVTGTVSNTGNTWFKLLIKPGCDSTEEEGDAWYLRPGDVVHQPELRQPGNHYLVYN
                     DKFIKISDSCPAKPPSAD"
     gene            complement(305174..306817)
                     /gene="ecpD"
                     /locus_tag="b0290"
                     /gene_synonym="ECK0289; JW0284; matE; yagW"
                     /db_xref="EcoGene:EG13562"
                     /db_xref="GeneID:947349"
     CDS             complement(305174..306817)
                     /gene="ecpD"
                     /locus_tag="b0290"
                     /gene_synonym="ECK0289; JW0284; matE; yagW"
                     /function="structural component; Surface structures"
                     /note="putative receptor"
                     /codon_start=1
                     /transl_table=11
                     /product="polymerized tip adhesin of ECP fibers"
                     /protein_id="NP_414824.1"
                     /db_xref="GI:16128275"
                     /db_xref="ASAP:ABE-0001002"
                     /db_xref="UniProtKB/Swiss-Prot:P77694"
                     /db_xref="EcoGene:EG13562"
                     /db_xref="GeneID:947349"
                     /translation="MRVNLLITMIIFALIWPVTALRAAVSKTTWADAPAREFVFVENN
                     SDDNFFVTPGGALDPRLTGANRWTGLKYTGSGTIYQQSLGYIDNGYNTGLYTNWKFDM
                     WLENSPVSSPLTGLRCINWYAGCNMTTSLILPQTTDASGFYGATVTSGGAKWMHGMLS
                     DAFYQYMQQMPVGSSFTMTINACQTSVNYDASSGARCKDQASGNWYVRNVTHTKAANL
                     RLINTHSLAEVFINSDGVPTLGEGNADCRTQTIGSRSGLSCKMVNYTLQTNGLSNTSI
                     HIFPAIANSSLASAVGAYDMQFSLNGSSWKPVSNTAYYYTFNEMKSADSIYVFFSSNF
                     FKQMVNLGISDINTKDLFNFRFQNTTSPESGWYEFSTSNTLIIKPRDFSISIISDEYT
                     QTPSREGYVGSGESALDFGYIVTTSGKTAADEVLIKVTGPAQVIGGRSYCVFSSDDGK
                     AKVPFPATLSFITRNGATKTYDAGCDDSWRDMTDALWLTTPWTDISGEVGQMDKTTVK
                     FSIPMDNAISLRTVDDNGWFGEVSASGEIHVQATWRNIN"
     gene            complement(306807..309332)
                     /gene="ecpC"
                     /locus_tag="b0291"
                     /gene_synonym="ECK0290; JW0285; matD; yagX"
                     /db_xref="EcoGene:EG13563"
                     /db_xref="GeneID:947606"
     CDS             complement(306807..309332)
                     /gene="ecpC"
                     /locus_tag="b0291"
                     /gene_synonym="ECK0290; JW0285; matD; yagX"
                     /function="membrane; Outer membrane constituents"
                     /note="putative enzyme"
                     /codon_start=1
                     /transl_table=11
                     /product="ECP production outer membrane protein"
                     /protein_id="NP_414825.1"
                     /db_xref="GI:16128276"
                     /db_xref="ASAP:ABE-0001005"
                     /db_xref="UniProtKB/Swiss-Prot:P77802"
                     /db_xref="EcoGene:EG13563"
                     /db_xref="GeneID:947606"
                     /translation="MPLRRFSPGLKAQFAFGMVFLFVQPDASAADISAQQIGGVIIPQ
                     AFSQALQDGMSVPLYIHLAGSQGRQDDQRIGSAFIWLDDGQLRIRKIQLEESEDNASV
                     SEQTRQQLMALANAPFNEALTIPLTDNAQLDLSLRQLLLQLVVKREALGTVLRSRSED
                     IGQSSVNTLSSNLSYNLGVYNNQLRNGGSNTSSYLSLNNVTALREHHVVLDGSLYGIG
                     SGQQDSELYKAMYERDFAGHRFAGGMLDTWNLQSLGPMTAISAGKIYGLSWGNQASST
                     IFDSSQSATPVIAFLPAAGEVHLTRDGRLLSVQNFTMGNHEVDTRGLPYGIYDVEVEV
                     IVNGRVISKRTQRVNKLFSRGRGVGAPLAWQVWGGSFHMDRWSENGKKTRPAKESWLA
                     GASTSGSLSTLSWAATGYGYDNQAVGETRLTLPLGGAINVNLQNMLASDSSWSSIGSI
                     SATLPGGFSSLWVNQEKTRIGNQLRRSDADNRAIGGTLNLNSLWSKLGTFSISYNDDR
                     RYNSHYYTADYYQNVYSGTFGSLGLRAGIQRYNNGDSNANTGKYIALDLSLPLGNWFS
                     AGMTHQNGYTMANLSARKQFDEGTIRTVGANLSRAISGDTGDDKTLSGGAYAQFDARY
                     ASGTLNVNSAADGYVNTNLTANGSVGWQGKNIAASGRTDGNAGVIFNTGLEDDGQISA
                     KINGRIFPLNGKRNYLPLSPYGRYEVELQNSKNSLDSYDIVSGRKSRLTLYPGNVAVI
                     EPEVKQMVTVSGRIRAEDGTLLANARINNHIGRTRTDENGEFVMDVDKKYPTIDFRYS
                     GNKTCEVALELNQARGAVWVGDVVCSGLSSWAAVTQTGEENES"
     misc_feature    complement(306861..>308645)
                     /gene="ecpC"
                     /locus_tag="b0291"
                     /gene_synonym="ECK0290; JW0285; matD; yagX"
                     /note="fimbrial outer membrane usher protein TcfC;
                     Provisional; Region: PRK15310"
                     /db_xref="CDD:185210"
     misc_feature    complement(307326..>307874)
                     /gene="ecpC"
                     /locus_tag="b0291"
                     /gene_synonym="ECK0290; JW0285; matD; yagX"
                     /note="Outer membrane usher protein; Region: Usher;
                     pfam00577"
                     /db_xref="CDD:249973"
     misc_feature    complement(<306903..307088)
                     /gene="ecpC"
                     /locus_tag="b0291"
                     /gene_synonym="ECK0290; JW0285; matD; yagX"
                     /note="Domain of unknown function (DUF4480); Region:
                     DUF4480; pfam13715"
                     /db_xref="CDD:258012"
     gene            complement(309358..310026)
                     /gene="ecpB"
                     /locus_tag="b0292"
                     /gene_synonym="ECK0291; JW0286; matC; yagY"
                     /db_xref="EcoGene:EG13564"
                     /db_xref="GeneID:948806"
     CDS             complement(309358..310026)
                     /gene="ecpB"
                     /locus_tag="b0292"
                     /gene_synonym="ECK0291; JW0286; matC; yagY"
                     /function="factor; Surface structures"
                     /codon_start=1
                     /transl_table=11
                     /product="ECP production pilus chaperone"
                     /protein_id="NP_414826.1"
                     /db_xref="GI:16128277"
                     /db_xref="ASAP:ABE-0001007"
                     /db_xref="UniProtKB/Swiss-Prot:P77188"
                     /db_xref="EcoGene:EG13564"
                     /db_xref="GeneID:948806"
                     /translation="MKKHLLPLALLFSGISPAQALDVGDISSFMNSDSSTLSKTIKNS
                     TDSGRLINIRLERLSSPLDDGQVISMDKPDELLLTPASLLLPAQASEVIRFFYKGPAD
                     EKERYYRIVWFDQALSDAQRDNANRSAVATASARIGTILVVAPRQANYHFQYANGSLT
                     NTGNATLRILAYGPCLKAANGKECKENYYLMPGKSRRFTRVDTADNKGRVALWQGDKF
                     IPVK"
     misc_feature    complement(<309502..310014)
                     /gene="ecpB"
                     /locus_tag="b0292"
                     /gene_synonym="ECK0291; JW0286; matC; yagY"
                     /note="putative fimbrial protein TcfA; Provisional;
                     Region: PRK15308"
                     /db_xref="CDD:237939"
     gene            complement(310084..310671)
                     /gene="ecpA"
                     /locus_tag="b0293"
                     /gene_synonym="ECK0292; JW0287; matB; yagZ"
                     /db_xref="EcoGene:EG13565"
                     /db_xref="GeneID:948759"
     CDS             complement(310084..310671)
                     /gene="ecpA"
                     /locus_tag="b0293"
                     /gene_synonym="ECK0292; JW0287; matB; yagZ"
                     /function="structural component; Surface structures"
                     /codon_start=1
                     /transl_table=11
                     /product="ECP pilin"
                     /protein_id="NP_414827.1"
                     /db_xref="GI:16128278"
                     /db_xref="ASAP:ABE-0001009"
                     /db_xref="UniProtKB/Swiss-Prot:P0AAA3"
                     /db_xref="EcoGene:EG13565"
                     /db_xref="GeneID:948759"
                     /translation="MKKKVLAIALVTVFTGMGVAQAADVTAQAVATWSATAKKDTTSK
                     LVVTPLGSLAFQYAEGIKGFNSQKGLFDVAIEGDSTATAFKLTSRLITNTLTQLDTSG
                     STLNVGVDYNGAAVEKTGDTVMIDTANGVLGGNLSPLANGYNASNRTTAQDGFTFSII
                     SGTTNGTTAVTDYSTLPEGIWSGDVSVQFDATWTS"
     gene            complement(310746..311336)
                     /gene="ecpR"
                     /locus_tag="b0294"
                     /gene_synonym="ECK0293; JW5031; matA; ykgK"
                     /db_xref="EcoGene:EG14324"
                     /db_xref="GeneID:944966"
     CDS             complement(310746..311336)
                     /gene="ecpR"
                     /locus_tag="b0294"
                     /gene_synonym="ECK0293; JW5031; matA; ykgK"
                     /function="putative regulator; Not classified"
                     /note="putative regulator"
                     /codon_start=1
                     /transl_table=11
                     /product="putative transcriptional regulator for the ecp
                     operon"
                     /protein_id="NP_414828.1"
                     /db_xref="GI:16128279"
                     /db_xref="ASAP:ABE-0001011"
                     /db_xref="UniProtKB/Swiss-Prot:P71301"
                     /db_xref="EcoGene:EG14324"
                     /db_xref="GeneID:944966"
                     /translation="MTWQSDYSRDYEVKNHMECQNRSDKYIWSPHDAYFYKGLSELIV
                     DIDRLIYLSLEKIRKDFVFINLSTDSLSEFINRDNEWLSAVKGKQVVLIAARKSEALA
                     NYWYYNSNIRGVVYAGLSRDIRKELVYVINGRFLRKDIKKDKITDREMEIIRMTAQGM
                     QPKSIARIENCSVKTVYTHRRNAEAKLYSKIYKLVQ"
     misc_feature    complement(310776..>311081)
                     /gene="ecpR"
                     /locus_tag="b0294"
                     /gene_synonym="ECK0293; JW5031; matA; ykgK"
                     /note="DNA-binding transcriptional activator UhpA;
                     Provisional; Region: PRK10360"
                     /db_xref="CDD:182408"
     misc_feature    complement(<310776..310901)
                     /gene="ecpR"
                     /locus_tag="b0294"
                     /gene_synonym="ECK0293; JW5031; matA; ykgK"
                     /note="C-terminal DNA-binding domain of LuxR-like
                     proteins. This domain contains a helix-turn-helix motif
                     and binds DNA. Proteins belonging to this group are
                     response regulators; some act as transcriptional
                     activators, others as transcriptional repressors. Many...;
                     Region: LuxR_C_like; cd06170"
                     /db_xref="CDD:99777"
     misc_feature    complement(order(310794..310808,310812..310817,
                     310821..310826,310848..310856,310893..310901))
                     /gene="ecpR"
                     /locus_tag="b0294"
                     /gene_synonym="ECK0293; JW5031; matA; ykgK"
                     /note="DNA binding residues [nucleotide binding]"
                     /db_xref="CDD:99777"
     gene            312112..312339
                     /gene="ykgL"
                     /locus_tag="b0295"
                     /gene_synonym="ECK0294; JW5033"
                     /db_xref="EcoGene:EG14325"
                     /db_xref="GeneID:944962"
     CDS             312112..312339
                     /gene="ykgL"
                     /locus_tag="b0295"
                     /gene_synonym="ECK0294; JW5033"
                     /codon_start=1
                     /transl_table=11
                     /product="uncharacterized protein"
                     /protein_id="NP_414829.1"
                     /db_xref="GI:16128280"
                     /db_xref="ASAP:ABE-0001019"
                     /db_xref="UniProtKB/Swiss-Prot:P56257"
                     /db_xref="EcoGene:EG14325"
                     /db_xref="GeneID:944962"
                     /translation="MQAAPQREETEWRVQSKRGLMPAYRGEAGQQVNIKIMEYSERNV
                     RQLASNEQEEYIPRKINVGVINTPTLIRSDY"
     gene            complement(312374..312514)
                     /gene="ykgO"
                     /locus_tag="b4506"
                     /gene_synonym="ECK0295; JW5034; rpmJ2"
                     /db_xref="EcoGene:EG14432"
                     /db_xref="GeneID:1450238"
     CDS             complement(312374..312514)
                     /gene="ykgO"
                     /locus_tag="b4506"
                     /gene_synonym="ECK0295; JW5034; rpmJ2"
                     /codon_start=1
                     /transl_table=11
                     /product="RpmJ-like protein"
                     /protein_id="YP_588437.1"
                     /db_xref="GI:94541137"
                     /db_xref="ASAP:ABE-0285027"
                     /db_xref="UniProtKB/Swiss-Prot:Q2EEQ2"
                     /db_xref="EcoGene:EG14432"
                     /db_xref="GeneID:1450238"
                     /translation="MKVLNSLRTAKERHPDCQIVKRKGRLYVICKSNPRFKAVQGRKK
                     KR"
     misc_feature    complement(312392..312514)
                     /gene="ykgO"
                     /locus_tag="b4506"
                     /gene_synonym="ECK0295; JW5034; rpmJ2"
                     /note="50S ribosomal protein L36; Validated; Region: rpmJ;
                     PRK00831"
                     /db_xref="CDD:179138"
     gene            complement(312514..312777)
                     /gene="ykgM"
                     /locus_tag="b0296"
                     /gene_synonym="ECK0296; JW5035; rpmE2"
                     /db_xref="EcoGene:EG14326"
                     /db_xref="GeneID:944960"
     CDS             complement(312514..312777)
                     /gene="ykgM"
                     /locus_tag="b0296"
                     /gene_synonym="ECK0296; JW5035; rpmE2"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L31 type B; alternative
                     zinc-limitation L31 protein"
                     /protein_id="NP_414830.1"
                     /db_xref="GI:16128281"
                     /db_xref="ASAP:ABE-0001021"
                     /db_xref="UniProtKB/Swiss-Prot:P0A7N1"
                     /db_xref="EcoGene:EG14326"
                     /db_xref="GeneID:944960"
                     /translation="MKPNIHPEYRTVVFHDTSVDEYFKIGSTIKTDREIELDGVTYPY
                     VTIDVSSKSHPFYTGKLRTVASEGNVARFTQRFGRFVSTKKGA"
     misc_feature    complement(312520..312777)
                     /gene="ykgM"
                     /locus_tag="b0296"
                     /gene_synonym="ECK0296; JW5035; rpmE2"
                     /note="50S ribosomal protein L31 type B; Reviewed; Region:
                     rpmE2; PRK01678"
                     /db_xref="CDD:234969"
     gene            complement(313141..313242)
                     /gene="ykgR"
                     /locus_tag="b4671"
                     /gene_synonym="ECK4486"
                     /db_xref="EcoGene:EG14476"
                     /db_xref="GeneID:7751635"
     CDS             complement(313141..313242)
                     /gene="ykgR"
                     /locus_tag="b4671"
                     /gene_synonym="ECK4486"
                     /codon_start=1
                     /transl_table=11
                     /product="uncharacterized protein"
                     /protein_id="YP_002791238.1"
                     /db_xref="GI:226524699"
                     /db_xref="UniProtKB/Swiss-Prot:C1P5Z8"
                     /db_xref="EcoGene:EG14476"
                     /db_xref="GeneID:7751635"
                     /translation="MKENKVQQISHKLINIVVFVAIVEYAYLFLHFY"
     gene            complement(313716..313805)
                     /gene="ykgP"
                     /locus_tag="b4630"
                     /gene_synonym="ECK4446"
                     /pseudo
                     /db_xref="EcoGene:EG14433"
                     /db_xref="GeneID:5625556"
     CDS             complement(313716..313805)
                     /gene="ykgP"
                     /locus_tag="b4630"
                     /gene_synonym="ECK4446"
                     /note="pseudogene, oxidoreductase family"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /db_xref="EcoGene:EG14433"
                     /db_xref="GeneID:5625556"
     gene            314357..315228
                     /gene="eaeH"
                     /locus_tag="b0297"
                     /gene_synonym="ECK0297; JW0291"
                     /pseudo
                     /db_xref="EcoGene:EG12161"
                     /db_xref="GeneID:944957"
     CDS             314357..315228
                     /gene="eaeH"
                     /locus_tag="b0297"
                     /gene_synonym="ECK0297; JW0291"
                     /GO_component="GO:0009274 - peptidoglycan-based cell wall"
                     /GO_component="GO:0009279 - cell outer membrane"
                     /note="pseudogene, attaching and effacing protein
                     homology;factor; Not classified"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /db_xref="ASAP:ABE-0001025"
                     /db_xref="UniProtKB/Swiss-Prot:P36943"
                     /db_xref="EcoGene:EG12161"
                     /db_xref="GeneID:944957"
     mobile_element  315229..316483
                     /mobile_element_type="insertion sequence:IS3A"
     gene            315291..315590
                     /gene="insE1"
                     /locus_tag="b0298"
                     /gene_synonym="ECK0298"
                     /db_xref="EcoGene:EG40005"
                     /db_xref="GeneID:944952"
     CDS             315291..315590
                     /gene="insE1"
                     /locus_tag="b0298"
                     /gene_synonym="ECK0298"
                     /function="IS, phage, Tn; Transposon-related functions;
                     extrachromosomal; transposon related"
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 transposase A"
                     /protein_id="NP_414832.2"
                     /db_xref="GI:226524700"
                     /db_xref="ASAP:ABE-0001028"
                     /db_xref="UniProtKB/Swiss-Prot:P0CF66"
                     /db_xref="EcoGene:EG40005"
                     /db_xref="GeneID:944952"
                     /translation="MTKTVSTSKKPRKQHSPEFRSEALKLAERIGVTAAARELSLYES
                     QLYNWRSKQQNQQTSSERELEMSTEIARLKRQLAERDEELAILQKAATYFAKRLK"
     misc_feature    315315..315527
                     /gene="insE1"
                     /locus_tag="b0298"
                     /gene_synonym="ECK0298"
                     /note="Transposase; Region: HTH_Tnp_1; cl17663"
                     /db_xref="CDD:266764"
     misc_feature    315318..315587
                     /gene="insE1"
                     /locus_tag="b0298"
                     /gene_synonym="ECK0298"
                     /note="Transposase and inactivated derivatives [DNA
                     replication, recombination, and repair]; Region: COG2963"
                     /db_xref="CDD:225511"
     gene            315587..316453
                     /gene="insF1"
                     /locus_tag="b0299"
                     /gene_synonym="ECK0299"
                     /db_xref="EcoGene:EG40006"
                     /db_xref="GeneID:944948"
     CDS             315587..316453
                     /gene="insF1"
                     /locus_tag="b0299"
                     /gene_synonym="ECK0299"
                     /function="IS, phage, Tn; Transposon-related functions;
                     extrachromosomal; transposon related"
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 transposase B"
                     /protein_id="NP_414833.1"
                     /db_xref="GI:16128284"
                     /db_xref="ASAP:ABE-0001030"
                     /db_xref="UniProtKB/Swiss-Prot:P0CF79"
                     /db_xref="EcoGene:EG40006"
                     /db_xref="GeneID:944948"
                     /translation="MKYVFIEKHQAEFSIKAMCRVLRVARSGWYTWCQRRTRISTRQQ
                     FRQHCDSVVLAAFTRSKQRYGAPRLTDELRAQGYPFNVKTVAASLRRQGLRAKASRKF
                     SPVSYRAHGLPVSENLLEQDFYASGPNQKWAGDITYLRTDEGWLYLAVVIDLWSRAVI
                     GWSMSPRMTAQLACDALQMALWRRKRPRNVIVHTDRGGQYCSADYQAQLKRHNLRGSM
                     SAKGCCYDNACVESFFHSLKVECIHGEHFISREIMRATVFNYIECDYNRWRRHSWCGG
                     LSPEQFENKNLA"
     misc_feature    315650..316450
                     /gene="insF1"
                     /locus_tag="b0299"
                     /gene_synonym="ECK0299"
                     /note="putative transposase OrfB; Reviewed; Region:
                     PHA02517"
                     /db_xref="CDD:222853"
     misc_feature    315722..315892
                     /gene="insF1"
                     /locus_tag="b0299"
                     /gene_synonym="ECK0299"
                     /note="HTH-like domain; Region: HTH_21; pfam13276"
                     /db_xref="CDD:257619"
     misc_feature    315959..316309
                     /gene="insF1"
                     /locus_tag="b0299"
                     /gene_synonym="ECK0299"
                     /note="Integrase core domain; Region: rve; pfam00665"
                     /db_xref="CDD:250040"
     misc_feature    316277..316447
                     /gene="insF1"
                     /locus_tag="b0299"
                     /gene_synonym="ECK0299"
                     /note="Integrase core domain; Region: rve_2; pfam13333"
                     /db_xref="CDD:257663"
     gene            complement(316486..317169)
                     /gene="ykgA"
                     /locus_tag="b0300"
                     /gene_synonym="ECK0300; JW5037"
                     /pseudo
                     /db_xref="EcoGene:EG13381"
                     /db_xref="GeneID:944956"
     CDS             complement(316486..317169)
                     /gene="ykgA"
                     /locus_tag="b0300"
                     /gene_synonym="ECK0300; JW5037"
                     /GO_function="GO:0016564 - transcription repressor
                     activity"
                     /GO_process="GO:0006350 - transcription"
                     /note="pseudogene, AraC family;putative regulator; Not
                     classified;
                     putative ARAC-type regulatory protein"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /db_xref="ASAP:ABE-0001032"
                     /db_xref="UniProtKB/Swiss-Prot:P77601"
                     /db_xref="EcoGene:EG13381"
                     /db_xref="GeneID:944956"
     gene            317439..317567
                     /gene="ykgQ"
                     /locus_tag="b4631"
                     /gene_synonym="ECK4454"
                     /pseudo
                     /db_xref="EcoGene:EG14443"
                     /db_xref="GeneID:5625557"
     CDS             317439..317567
                     /gene="ykgQ"
                     /locus_tag="b4631"
                     /gene_synonym="ECK4454"
                     /note="pseudogene, putative dehydrogenase"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /db_xref="EcoGene:EG14443"
                     /db_xref="GeneID:5625557"
     gene            complement(317726..318319)
                     /gene="rclC"
                     /locus_tag="b0301"
                     /gene_synonym="ECK0301; JW5038"
                     /db_xref="EcoGene:EG13579"
                     /db_xref="GeneID:944974"
     CDS             complement(317726..318319)
                     /gene="rclC"
                     /locus_tag="b0301"
                     /gene_synonym="ECK0301; JW5038"
                     /codon_start=1
                     /transl_table=11
                     /product="reactive chlorine species (RCS) stress
                     resistance inner membrane protein"
                     /protein_id="NP_414835.2"
                     /db_xref="GI:90111110"
                     /db_xref="ASAP:ABE-0001038"
                     /db_xref="UniProtKB/Swiss-Prot:P75685"
                     /db_xref="EcoGene:EG13579"
                     /db_xref="GeneID:944974"
                     /translation="MEKYLHLLSRGDKIGLTLIRLSIAIVFMWIGLLKFVPYEADSIT
                     PFVANSPLMSFFYEHPEDYKQYLTHEGEYKPEARAWQTANNTYGFSNGLGVVEVIIAL
                     LVLANPVNRWLGLLGGLMAFTTPLVTLSFLITTPEAWVPALGDAHHGFPYLSGAGRLV
                     LKDTLMLAGAVMIMADSAREILKQRSNESSSTLKTEY"
     misc_feature    complement(317762..318319)
                     /gene="rclC"
                     /locus_tag="b0301"
                     /gene_synonym="ECK0301; JW5038"
                     /note="Predicted membrane protein [Function unknown];
                     Region: COG3059"
                     /db_xref="CDD:225601"
     gene            complement(318331..318567)
                     /gene="rclB"
                     /locus_tag="b0303"
                     /gene_synonym="ECK0302; JW5039; ykgB; ykgI"
                     /db_xref="EcoGene:EG14278"
                     /db_xref="GeneID:945658"
     CDS             complement(318331..318567)
                     /gene="rclB"
                     /locus_tag="b0303"
                     /gene_synonym="ECK0302; JW5039; ykgB; ykgI"
                     /note="the overlapping ORF b0302 on the opposite strand is
                     no longer thought to be an actual gene, and has been
                     deaccessioned"
                     /codon_start=1
                     /transl_table=11
                     /product="reactive chlorine species (RCS) stress
                     resistance periplasmic protein"
                     /protein_id="NP_414837.2"
                     /db_xref="GI:90111111"
                     /db_xref="ASAP:ABE-0001043"
                     /db_xref="UniProtKB/Swiss-Prot:P75687"
                     /db_xref="EcoGene:EG14278"
                     /db_xref="GeneID:945658"
                     /translation="MFKKSVLFATLLSGVMAFSTNADDKIILKHISVSSVSASPTVLE
                     DTIADIARKYNASSWKVTSMRIDNNSTATAVLYK"
     misc_feature    complement(318334..318477)
                     /gene="rclB"
                     /locus_tag="b0303"
                     /gene_synonym="ECK0302; JW5039; ykgB; ykgI"
                     /note="Protein of unknown function (DUF1471); Region:
                     DUF1471; pfam07338"
                     /db_xref="CDD:254164"
     gene            complement(318676..320001)
                     /gene="rclA"
                     /locus_tag="b0304"
                     /gene_synonym="ECK0303; JW5040; ykgC"
                     /db_xref="EcoGene:EG13580"
                     /db_xref="GeneID:946092"
     CDS             complement(318676..320001)
                     /gene="rclA"
                     /locus_tag="b0304"
                     /gene_synonym="ECK0303; JW5040; ykgC"
                     /function="putative enzyme; Not classified"
                     /note="putative oxidoreductase"
                     /codon_start=1
                     /transl_table=11
                     /product="reactive chlorine stress species (RCS)
                     resistance protein; pyridine nucleotide-dependent
                     disulfide oxidoreductase family"
                     /protein_id="NP_414838.2"
                     /db_xref="GI:90111112"
                     /db_xref="ASAP:ABE-0001048"
                     /db_xref="UniProtKB/Swiss-Prot:P77212"
                     /db_xref="EcoGene:EG13580"
                     /db_xref="GeneID:946092"
                     /translation="MNKYQAVIIGFGKAGKTLAVTLAKAGWRVALIEQSNAMYGGTCI
                     NIGCIPTKTLVHDAQQHTDFVRAIQRKNEVVNFLRNKNFHNLADMPNIDVIDGQAEFI
                     NNHSLRVHRPEGNLEIHGEKIFINTGAQTVVPPIPGITTTPGVYDSTGLLNLKELPGH
                     LGILGGGYIGVEFASMFANFGSKVTILEAASLFLPREDRDIADNIATILRDQGVDIIL
                     NAHVERISHHENQVQVHSEHAQLAVDALLIASGRQPATASLHPENAGIAVNERGAIVV
                     DKRLHTTADNIWAMGDVTGGLQFTYISLDDYRIVRDELLGEGKRSTDDRKNVPYSVFM
                     TPPLSRVGMTEEQARESGADIQVVTLPVAAIPRARVMNDTRGVLKAIVDNKTQRMLGA
                     SLLCVDSHEMINIVKMVMDAGLPYSILRDQIFTHPSMSESLNDLFSLVK"
     misc_feature    complement(318679..320001)
                     /gene="rclA"
                     /locus_tag="b0304"
                     /gene_synonym="ECK0303; JW5040; ykgC"
                     /note="pyridine nucleotide-disulfide oxidoreductase;
                     Provisional; Region: PRK08010"
                     /db_xref="CDD:181196"
     misc_feature    complement(<319900..319995)
                     /gene="rclA"
                     /locus_tag="b0304"
                     /gene_synonym="ECK0303; JW5040; ykgC"
                     /note="Squalene epoxidase; Region: SE; cl17314"
                     /db_xref="CDD:266623"
     misc_feature    complement(319297..319491)
                     /gene="rclA"
                     /locus_tag="b0304"
                     /gene_synonym="ECK0303; JW5040; ykgC"
                     /note="Pyridine nucleotide-disulphide oxidoreductase;
                     Region: Pyr_redox; pfam00070"
                     /db_xref="CDD:249559"
     misc_feature    complement(318703..319020)
                     /gene="rclA"
                     /locus_tag="b0304"
                     /gene_synonym="ECK0303; JW5040; ykgC"
                     /note="Pyridine nucleotide-disulphide oxidoreductase,
                     dimerization domain; Region: Pyr_redox_dim; pfam02852"
                     /db_xref="CDD:251571"
     gene            320227..321081
                     /gene="rclR"
                     /locus_tag="b0305"
                     /gene_synonym="ECK0304; JW0298; ykgD"
                     /db_xref="EcoGene:EG13581"
                     /db_xref="GeneID:945616"
     CDS             320227..321081
                     /gene="rclR"
                     /locus_tag="b0305"
                     /gene_synonym="ECK0304; JW0298; ykgD"
                     /function="regulator; Not classified"
                     /GO_function="GO:0016563 - transcription activator
                     activity"
                     /GO_process="GO:0006350 - transcription"
                     /note="putative ARAC-type regulatory protein"
                     /codon_start=1
                     /transl_table=11
                     /product="reactive chlorine species (RCS)-specific
                     activator of the rcl genes"
                     /protein_id="NP_414839.1"
                     /db_xref="GI:16128290"
                     /db_xref="ASAP:ABE-0001054"
                     /db_xref="UniProtKB/Swiss-Prot:P77379"
                     /db_xref="EcoGene:EG13581"
                     /db_xref="GeneID:945616"
                     /translation="MDALSRLLMLNAPQGTIDKNCVLGSDWQLPHGAGELSVIRWHAL
                     TQGAAKLEMPTGEIFTLRPGNVVLLPQNSAHRLSHVDNESTCIVCGTLRLQHSARYFL
                     TSLPETLFLAPVNHSVEYNWLREAIPFLQQESRSAMPGVDALCSQICATFFTLAVREW
                     IAQVNTEKNILSLLLHPRLGAVIQQMLEMPGHAWTVESLASIAHMSRASFAQLFRDVS
                     GTTPLAVLTKLRLQIAAQMFSRETLPVVVIAESVGYASESSFHKAFVREFGCTPGEYR
                     ERVRQLAP"
     misc_feature    320230..320712
                     /gene="rclR"
                     /locus_tag="b0305"
                     /gene_synonym="ECK0304; JW0298; ykgD"
                     /note="Cupin; Region: Cupin_6; pfam12852"
                     /db_xref="CDD:257350"
     misc_feature    320710..321075
                     /gene="rclR"
                     /locus_tag="b0305"
                     /gene_synonym="ECK0304; JW0298; ykgD"
                     /note="AraC-type DNA-binding domain-containing proteins
                     [Transcription]; Region: AraC; COG2207"
                     /db_xref="CDD:225117"
     misc_feature    320782..320907
                     /gene="rclR"
                     /locus_tag="b0305"
                     /gene_synonym="ECK0304; JW0298; ykgD"
                     /note="Bacterial regulatory helix-turn-helix proteins,
                     AraC family; Region: HTH_AraC; pfam00165"
                     /db_xref="CDD:249644"
     misc_feature    <320968..321054
                     /gene="rclR"
                     /locus_tag="b0305"
                     /gene_synonym="ECK0304; JW0298; ykgD"
                     /note="Bacterial regulatory helix-turn-helix proteins,
                     AraC family; Region: HTH_AraC; pfam00165"
                     /db_xref="CDD:249644"
     gene            321608..322327
                     /gene="ykgE"
                     /locus_tag="b0306"
                     /gene_synonym="ECK0305; JW5041"
                     /db_xref="EcoGene:EG13582"
                     /db_xref="GeneID:948438"
     CDS             321608..322327
                     /gene="ykgE"
                     /locus_tag="b0306"
                     /gene_synonym="ECK0305; JW5041"
                     /function="putative carrier; Energy metabolism, carbon:
                     Electron transport"
                     /note="putative dehydrogenase subunit"
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine-rich LutA family protein; putative
                     electron transport chain YkgEFG component"
                     /protein_id="NP_414840.1"
                     /db_xref="GI:16128291"
                     /db_xref="ASAP:ABE-0001058"
                     /db_xref="UniProtKB/Swiss-Prot:P77252"
                     /db_xref="EcoGene:EG13582"
                     /db_xref="GeneID:948438"
                     /translation="MNVNFFVTCIGDALKSRMARDSVLLLEKLGCRVNFPEKQGCCGQ
                     PAINSGYIKEAIPGMKNLIAALEDNDDPIISPAGSCTYAVKSYPTYLADEPEWASRAA
                     KVAARMQDLTSFIVNKLGVVDVGASLQGRAVYHPSCSLARKLGVKDEPLTLLKNVRGL
                     ELLTFAEQDTCCGFGGTFSVKMAEISGEMVKEKVAHLMEVRPEYLIGADVSCLLNISG
                     RLQREGQKVKVMHIAEVLMSR"
     misc_feature    <321608..322324
                     /gene="ykgE"
                     /locus_tag="b0306"
                     /gene_synonym="ECK0305; JW5041"
                     /note="Fe-S oxidoreductase [Energy production and
                     conversion]; Region: GlpC; COG0247"
                     /db_xref="CDD:223325"
     misc_feature    321614..321862
                     /gene="ykgE"
                     /locus_tag="b0306"
                     /gene_synonym="ECK0305; JW5041"
                     /note="Cysteine-rich domain; Region: CCG; pfam02754"
                     /db_xref="CDD:202376"
     misc_feature    322001..322258
                     /gene="ykgE"
                     /locus_tag="b0306"
                     /gene_synonym="ECK0305; JW5041"
                     /note="Cysteine-rich domain; Region: CCG; pfam02754"
                     /db_xref="CDD:202376"
     gene            322338..323765
                     /gene="ykgF"
                     /locus_tag="b0307"
                     /gene_synonym="ECK0306; JW0300"
                     /db_xref="EcoGene:EG13583"
                     /db_xref="GeneID:944980"
     CDS             322338..323765
                     /gene="ykgF"
                     /locus_tag="b0307"
                     /gene_synonym="ECK0306; JW0300"
                     /function="putative carrier; Energy metabolism, carbon:
                     Electron transport"
                     /codon_start=1
                     /transl_table=11
                     /product="ferridoxin-like LutB family protein; putative
                     electron transport chain YkgEFG component"
                     /protein_id="NP_414841.1"
                     /db_xref="GI:16128292"
                     /db_xref="ASAP:ABE-0001060"
                     /db_xref="UniProtKB/Swiss-Prot:P77536"
                     /db_xref="EcoGene:EG13583"
                     /db_xref="GeneID:944980"
                     /translation="MSIKTSNTDFKTRIRQQIEDPIMRKAVANAQQRIGANRQKMVDE
                     LGHWEEWRDRAAQIRDHVLSNLDAYLYQLSEKVTQNGGHVYFARTKEDATRYILQVAQ
                     RKNARKVVKSKSMVTEEIGVNHVLQDAGIQVIETDLGEYILQLDQDPPSHVVVPAIHK
                     DRHQIRRVLHERLGYEGPETPEAMTLFIRQKIREDFLSAEIGITGCNFAVAETGSVCL
                     VTNEGNARMCTTLPKTHIAVMGMERIAPTFAEVDVLITMLARSAVGARLTGYNTWLTG
                     PREAGHVDGPEEFHLVIVDNGRSEVLASEFRDVLRCIRCGACMNTCPAYRHIGGHGYG
                     SIYPGPIGAVISPLLGGYKDFKDLPYACSLCTACDNVCPVRIPLSKLILRHRRVMAEK
                     GITAKAEQRAIKMFAYANSHPGLWKVGMMAGAHAASWFINGGKTPLKFGAISDWMEAR
                     DLPEADGESFRSWFKKHQAQEKKNG"
     misc_feature    322389..323696
                     /gene="ykgF"
                     /locus_tag="b0307"
                     /gene_synonym="ECK0306; JW0300"
                     /note="iron-sulfur cluster-binding protein; Region:
                     TIGR00273"
                     /db_xref="CDD:129374"
     misc_feature    322551..323219
                     /gene="ykgF"
                     /locus_tag="b0307"
                     /gene_synonym="ECK0306; JW0300"
                     /note="Uncharacterized ACR, YkgG family COG1556; Region:
                     DUF162; pfam02589"
                     /db_xref="CDD:251397"
     misc_feature    323259..323465
                     /gene="ykgF"
                     /locus_tag="b0307"
                     /gene_synonym="ECK0306; JW0300"
                     /note="4Fe-4S dicluster domain; Region: Fer4_8; pfam13183"
                     /db_xref="CDD:257551"
     misc_feature    323490..323750
                     /gene="ykgF"
                     /locus_tag="b0307"
                     /gene_synonym="ECK0306; JW0300"
                     /note="Domain of unknown function (DUF3390); Region:
                     DUF3390; pfam11870"
                     /db_xref="CDD:256687"
     gene            323758..324453
                     /gene="ykgG"
                     /locus_tag="b0308"
                     /gene_synonym="ECK0307; JW5042"
                     /db_xref="EcoGene:EG13584"
                     /db_xref="GeneID:945906"
     CDS             323758..324453
                     /gene="ykgG"
                     /locus_tag="b0308"
                     /gene_synonym="ECK0307; JW5042"
                     /function="putative carrier; Energy metabolism, carbon:
                     Electron transport"
                     /note="putative transporter"
                     /codon_start=1
                     /transl_table=11
                     /product="LutC family protein; putative electron transport
                     chain YkgEFG component"
                     /protein_id="NP_414842.4"
                     /db_xref="GI:90111113"
                     /db_xref="ASAP:ABE-0001062"
                     /db_xref="UniProtKB/Swiss-Prot:P77433"
                     /db_xref="EcoGene:EG13584"
                     /db_xref="GeneID:945906"
                     /translation="MDNRGEFLNNVAQALGRPLRLEPQAEDAPLNNYANERLTQLNQQ
                     QRCDAFIQFASDVMLTRCELTSEAKAAEAAIRLCKELGDQSVVISGDTRLEELGISER
                     LQQECNAVVWDPAKGAENISQAEQAKVGVVYAEYGLTESGGVVLFSAAERGRSLSLLP
                     EYSLFILRKSTILPRVAQLAEKLHQKAQAGERMPSCINIISGPSSTADIELIKVVGVH
                     GPVKAVYLIIEDC"
     misc_feature    323758..324450
                     /gene="ykgG"
                     /locus_tag="b0308"
                     /gene_synonym="ECK0307; JW5042"
                     /note="Uncharacterized conserved protein [Function
                     unknown]; Region: COG1556"
                     /db_xref="CDD:224473"
     gene            complement(324696..325364)
                     /gene="ykgH"
                     /locus_tag="b0310"
                     /gene_synonym="ECK0308; JW0302"
                     /db_xref="EcoGene:EG13585"
                     /db_xref="GeneID:947513"
     CDS             complement(324696..325364)
                     /gene="ykgH"
                     /locus_tag="b0310"
                     /gene_synonym="ECK0308; JW0302"
                     /codon_start=1
                     /transl_table=11
                     /product="putative inner membrane protein"
                     /protein_id="NP_414844.1"
                     /db_xref="GI:16128295"
                     /db_xref="ASAP:ABE-0001066"
                     /db_xref="UniProtKB/Swiss-Prot:P77180"
                     /db_xref="EcoGene:EG13585"
                     /db_xref="GeneID:947513"
                     /translation="MREQIKQDIDLIEILFYLKKKIRVILFIMAICMAMVLLFLYINK
                     DNIKVIYSLKINQTTPGILVSCDSNNNFACQTTMTEDVIQRITTFFHTSPDVKNREIR
                     LEWSGDKRALPTAEEEISRVQASIIKWYASEYHNGRQVLDEIQTPSAINSELYTKMIY
                     LTRNWSLYPNGDGCVTISSPEIKNKYPAAICLALGFFLSIVISVMFCLVKKMVDEYQQ
                     NSGQ"
     misc_feature    complement(324729..324962)
                     /gene="ykgH"
                     /locus_tag="b0310"
                     /gene_synonym="ECK0308; JW0302"
                     /note="G-rich domain on putative tyrosine kinase; Region:
                     GNVR; pfam13807"
                     /db_xref="CDD:258087"
     gene            complement(325577..327247)
                     /gene="betA"
                     /locus_tag="b0311"
                     /gene_synonym="ECK0309; JW0303"
                     /db_xref="EcoGene:EG10109"
                     /db_xref="GeneID:945716"
     CDS             complement(325577..327247)
                     /gene="betA"
                     /locus_tag="b0311"
                     /gene_synonym="ECK0309; JW0303"
                     /EC_number="1.1.99.1"
                     /function="enzyme; Osmotic adaptation"
                     /GO_component="GO:0009274 - peptidoglycan-based cell wall"
                     /GO_component="GO:0019866 - organelle inner membrane"
                     /GO_process="GO:0006578 - betaine biosynthetic process"
                     /GO_process="GO:0006970 - response to osmotic stress"
                     /codon_start=1
                     /transl_table=11
                     /product="choline dehydrogenase, a flavoprotein"
                     /protein_id="NP_414845.1"
                     /db_xref="GI:16128296"
                     /db_xref="ASAP:ABE-0001070"
                     /db_xref="UniProtKB/Swiss-Prot:P17444"
                     /db_xref="EcoGene:EG10109"
                     /db_xref="GeneID:945716"
                     /translation="MQFDYIIIGAGSAGNVLATRLTEDPNTSVLLLEAGGPDYRFDFR
                     TQMPAALAFPLQGKRYNWAYETEPEPFMNNRRMECGRGKGLGGSSLINGMCYIRGNAL
                     DLDNWAQEPGLENWSYLDCLPYYRKAETRDMGENDYHGGDGPVSVTTSKPGVNPLFEA
                     MIEAGVQAGYPRTDDLNGYQQEGFGPMDRTVTPQGRRASTARGYLDQAKSRPNLTIRT
                     HAMTDHIIFDGKRAVGVEWLEGDSTIPTRATANKEVLLCAGAIASPQILQRSGVGNAE
                     LLAEFDIPLVHELPGVGENLQDHLEMYLQYECKEPVSLYPALQWWNQPKIGAEWLFGG
                     TGVGASNHFEAGGFIRSREEFAWPNIQYHFLPVAINYNGSNAVKEHGFQCHVGSMRSP
                     SRGHVRIKSRDPHQHPAILFNYMSHEQDWQEFRDAIRITREIMHQPALDQYRGREISP
                     GVECQTDEQLDEFVRNHAETAFHPCGTCKMGYDEMSVVDGEGRVHGLEGLRVVDASIM
                     PQIITGNLNATTIMIGEKIADMIRGQEALPRSTAGYFVANGMPVRAKK"
     misc_feature    complement(325583..327247)
                     /gene="betA"
                     /locus_tag="b0311"
                     /gene_synonym="ECK0309; JW0303"
                     /note="choline dehydrogenase; Validated; Region: PRK02106"
                     /db_xref="CDD:235000"
     misc_feature    complement(<327044..327238)
                     /gene="betA"
                     /locus_tag="b0311"
                     /gene_synonym="ECK0309; JW0303"
                     /note="NAD(P)-binding Rossmann-like domain; Region:
                     NAD_binding_8; cl19134"
                     /db_xref="CDD:267487"
     misc_feature    complement(326345..327031)
                     /gene="betA"
                     /locus_tag="b0311"
                     /gene_synonym="ECK0309; JW0303"
                     /note="GMC oxidoreductase; Region: GMC_oxred_N; pfam00732"
                     /db_xref="CDD:250093"
     misc_feature    complement(325673..326071)
                     /gene="betA"
                     /locus_tag="b0311"
                     /gene_synonym="ECK0309; JW0303"
                     /note="GMC oxidoreductase; Region: GMC_oxred_C; pfam05199"
                     /db_xref="CDD:253079"
     gene            complement(327261..328733)
                     /gene="betB"
                     /locus_tag="b0312"
                     /gene_synonym="ECK0310; JW0304"
                     /db_xref="EcoGene:EG10110"
                     /db_xref="GeneID:947376"
     CDS             complement(327261..328733)
                     /gene="betB"
                     /locus_tag="b0312"
                     /gene_synonym="ECK0310; JW0304"
                     /EC_number="1.2.1.8"
                     /function="enzyme; Osmotic adaptation"
                     /GO_process="GO:0006578 - betaine biosynthetic process"
                     /GO_process="GO:0006970 - response to osmotic stress"
                     /note="NAD+-dependent betaine aldehyde dehydrogenase"
                     /codon_start=1
                     /transl_table=11
                     /product="betaine aldehyde dehydrogenase, NAD-dependent"
                     /protein_id="NP_414846.1"
                     /db_xref="GI:16128297"
                     /db_xref="ASAP:ABE-0001072"
                     /db_xref="UniProtKB/Swiss-Prot:P17445"
                     /db_xref="EcoGene:EG10110"
                     /db_xref="GeneID:947376"
                     /translation="MSRMAEQQLYIHGGYTSATSGRTFETINPANGNVLATVQAAGRE
                     DVDRAVKSAQQGQKIWASMTAMERSRILRRAVDILRERNDELAKLETLDTGKAYSETS
                     TVDIVTGADVLEYYAGLIPALEGSQIPLRETSFVYTRREPLGVVAGIGAWNYPIQIAL
                     WKSAPALAAGNAMIFKPSEVTPLTALKLAEIYSEAGLPDGVFNVLPGVGAETGQYLTE
                     HPGIAKVSFTGGVASGKKVMANSAASSLKEVTMELGGKSPLIVFDDADLDLAADIAMM
                     ANFFSSGQVCTNGTRVFVPAKCKAAFEQKILARVERIRAGDVFDPQTNFGPLVSFPHR
                     DNVLRYIAKGKEEGARVLCGGDVLKGDGFDNGAWVAPTVFTDCSDDMTIVREEIFGPV
                     MSILTYESEDEVIRRANDTDYGLAAGIVTADLNRAHRVIHQLEAGICWINTWGESPAE
                     MPVGGYKHSGIGRENGVMTLQSYTQVKSIQVEMAKFQSIF"
     misc_feature    complement(327285..328658)
                     /gene="betB"
                     /locus_tag="b0312"
                     /gene_synonym="ECK0310; JW0304"
                     /note="NAD+-dependent 4-trimethylaminobutyraldehyde
                     dehydrogenase, ALDH family 9A1; Region: ALDH_F9_TMBADH;
                     cd07090"
                     /db_xref="CDD:143409"
     misc_feature    complement(order(327285..327290,327294..327311,
                     327345..327347,327351..327353,327360..327362,
                     327366..327368,327378..327380,327384..327386,
                     327408..327413,327417..327428,327432..327434,
                     327441..327443,327447..327452,327459..327470,
                     327762..327764,327807..327809,327906..327911,
                     327918..327920,327927..327929,327993..327995,
                     328029..328031,328311..328319,328323..328325,
                     328347..328361,328380..328382,328392..328394,
                     328494..328496,328503..328505,328515..328517,
                     328524..328526,328536..328538,328542..328544))
                     /gene="betB"
                     /locus_tag="b0312"
                     /gene_synonym="ECK0310; JW0304"
                     /note="tetrameric interface [polypeptide binding]; other
                     site"
                     /db_xref="CDD:143409"
     misc_feature    complement(order(327375..327377,327567..327569,
                     327573..327575,327876..327878,327972..327980,
                     328035..328037,328044..328049,328053..328055,
                     328107..328109,328206..328208,328275..328280,
                     328284..328289))
                     /gene="betB"
                     /locus_tag="b0312"
                     /gene_synonym="ECK0310; JW0304"
                     /note="NAD binding site [chemical binding]; other site"
                     /db_xref="CDD:143409"
     misc_feature    complement(order(327876..327878,327885..327887,
                     327978..327980,328275..328277))
                     /gene="betB"
                     /locus_tag="b0312"
                     /gene_synonym="ECK0310; JW0304"
                     /note="catalytic residues [active]"
                     /db_xref="CDD:143409"
     gene            complement(328747..329334)
                     /gene="betI"
                     /locus_tag="b0313"
                     /gene_synonym="ECK0311; JW0305"
                     /db_xref="EcoGene:EG10111"
                     /db_xref="GeneID:944981"
     CDS             complement(328747..329334)
                     /gene="betI"
                     /locus_tag="b0313"
                     /gene_synonym="ECK0311; JW0305"
                     /function="putative regulator; Osmotic adaptation"
                     /GO_function="GO:0016564 - transcription repressor
                     activity"
                     /GO_process="GO:0006350 - transcription"
                     /GO_process="GO:0006970 - response to osmotic stress"
                     /note="probably transcriptional repressor of bet genes"
                     /codon_start=1
                     /transl_table=11
                     /product="choline-inducible betIBA-betT divergent operon
                     transcriptional repressor"
                     /protein_id="NP_414847.3"
                     /db_xref="GI:49176011"
                     /db_xref="ASAP:ABE-0001076"
                     /db_xref="UniProtKB/Swiss-Prot:P17446"
                     /db_xref="EcoGene:EG10111"
                     /db_xref="GeneID:944981"
                     /translation="MPKLGMQSIRRRQLIDATLEAINEVGMHDATIAQIARRAGVSTG
                     IISHYFRDKNGLLEATMRDITSQLRDAVLNRLHALPQGSAEQRLQAIVGGNFDETQVS
                     SAAMKAWLAFWASSMHQPMLYRLQQVSSRRLLSNLVSEFRRELPREQAQEAGYGLAAL
                     IDGLWLRAALSGKPLDKTRANSLTRHFITQHLPTD"
     misc_feature    complement(328753..329334)
                     /gene="betI"
                     /locus_tag="b0313"
                     /gene_synonym="ECK0311; JW0305"
                     /note="transcriptional regulator BetI; Validated; Region:
                     PRK00767"
                     /db_xref="CDD:179115"
     misc_feature    complement(329158..329295)
                     /gene="betI"
                     /locus_tag="b0313"
                     /gene_synonym="ECK0311; JW0305"
                     /note="Bacterial regulatory proteins, tetR family; Region:
                     TetR_N; pfam00440"
                     /db_xref="CDD:249860"
     misc_feature    complement(328756..329085)
                     /gene="betI"
                     /locus_tag="b0313"
                     /gene_synonym="ECK0311; JW0305"
                     /note="Bacterial transcriptional repressor; Region:
                     TetR_C_6; pfam13977"
                     /db_xref="CDD:258229"
     gene            329463..331496
                     /gene="betT"
                     /locus_tag="b0314"
                     /gene_synonym="ECK0312; JW0306"
                     /db_xref="EcoGene:EG10112"
                     /db_xref="GeneID:945079"
     CDS             329463..331496
                     /gene="betT"
                     /locus_tag="b0314"
                     /gene_synonym="ECK0312; JW0306"
                     /function="transport; Transport of small molecules: Other"
                     /GO_component="GO:0009274 - peptidoglycan-based cell wall"
                     /GO_component="GO:0019866 - organelle inner membrane"
                     /GO_process="GO:0006578 - betaine biosynthetic process"
                     /note="high-affinity choline transport"
                     /codon_start=1
                     /transl_table=11
                     /product="choline transporter of high affinity"
                     /protein_id="NP_414848.1"
                     /db_xref="GI:16128299"
                     /db_xref="ASAP:ABE-0001080"
                     /db_xref="UniProtKB/Swiss-Prot:P0ABC9"
                     /db_xref="EcoGene:EG10112"
                     /db_xref="GeneID:945079"
                     /translation="MTDLSHSREKDKINPVVFYTSAGLILLFSLTTILFRDFSALWIG
                     RTLDWVSKTFGWYYLLAATLYIVFVVCIACSRFGSVKLGPEQSKPEFSLLSWAAMLFA
                     AGIGIDLMFFSVAEPVTQYMQPPEGAGQTIEAARQAMVWTLFHYGLTGWSMYALMGMA
                     LGYFSYRYNLPLTIRSALYPIFGKRINGPIGHSVDIAAVIGTIFGIATTLGIGVVQLN
                     YGLSVLFDIPDSMAAKAALIALSVIIATISVTSGVDKGIRVLSELNVALALGLILFVL
                     FMGDTSFLLNALVLNVGDYVNRFMGMTLNSFAFDRPVEWMNNWTLFFWAWWVAWSPFV
                     GLFLARISRGRTIRQFVLGTLIIPFTFTLLWLSVFGNSALYEIIHGGAAFAEEAMVHP
                     ERGFYSLLAQYPAFTFSASVATITGLLFYVTSADSGALVLGNFTSQLKDINSDAPGWL
                     RVFWSVAIGLLTLGMLMTNGISALQNTTVIMGLPFSFVIFFVMAGLYKSLKVEDYRRE
                     SANRDTAPRPLGLQDRLSWKKRLSRLMNYPGTRYTKQMMETVCYPAMEEVAQELRLRG
                     AYVELKSLPPEEGQQLGHLDLLVHMGEEQNFVYQIWPQQYSVPGFTYRARSGKSTYYR
                     LETFLLEGSQGNDLMDYSKEQVITDILDQYERHLNFIHLHREAPGHSVMFPDA"
     misc_feature    329463..331493
                     /gene="betT"
                     /locus_tag="b0314"
                     /gene_synonym="ECK0312; JW0306"
                     /note="choline transport protein BetT; Provisional;
                     Region: PRK09928"
                     /db_xref="CDD:236635"
     gene            332371..333459
                     /gene="yahA"
                     /locus_tag="b0315"
                     /gene_synonym="ECK0313; JW0307"
                     /db_xref="EcoGene:EG11236"
                     /db_xref="GeneID:947459"
     CDS             332371..333459
                     /gene="yahA"
                     /locus_tag="b0315"
                     /gene_synonym="ECK0313; JW0307"
                     /GO_process="GO:0006355 - regulation of transcription,
                     DNA-dependent"
                     /codon_start=1
                     /transl_table=11
                     /product="c-di-GMP-specific phosphodiesterase"
                     /protein_id="NP_414849.1"
                     /db_xref="GI:16128300"
                     /db_xref="ASAP:ABE-0001086"
                     /db_xref="UniProtKB/Swiss-Prot:P21514"
                     /db_xref="EcoGene:EG11236"
                     /db_xref="GeneID:947459"
                     /translation="MNSCDFRVFLQEFGTTVHLSLPGSVSEKERLLLKLLMQGMSVTE
                     ISQYRNRSAKTISHQKKQLFEKLGIQSDITFWRDIFFQYNPEIISATGSNSHRYINDN
                     HYHHIVTPEAISLALENHEFKPWIQPVFCAQTGVLTGCEVLVRWEHPQTGIIPPDQFI
                     PLAESSGLIVIMTRQLMKQTADILMPVKHLLPDNFHIGINVSAGCFLAAGFEKECLNL
                     VNKLGNDKIKLVLELTERNPIPVTPEARAIFDSLHQHNITFALDDFGTGYATYRYLQA
                     FPVDFIKIDKSFVQMASVDEISGHIVDNIVELARKPGLSIVAEGVETQEQADLMIGKG
                     VHFLQGYLYSPPVPGNKFISEWVMKAGG"
     misc_feature    332446..332610
                     /gene="yahA"
                     /locus_tag="b0315"
                     /gene_synonym="ECK0313; JW0307"
                     /note="C-terminal DNA-binding domain of LuxR-like
                     proteins. This domain contains a helix-turn-helix motif
                     and binds DNA. Proteins belonging to this group are
                     response regulators; some act as transcriptional
                     activators, others as transcriptional repressors. Many...;
                     Region: LuxR_C_like; cd06170"
                     /db_xref="CDD:99777"
     misc_feature    order(332446..332454,332491..332499,332521..332526,
                     332530..332535,332539..332553,332584..332586)
                     /gene="yahA"
                     /locus_tag="b0315"
                     /gene_synonym="ECK0313; JW0307"
                     /note="DNA binding residues [nucleotide binding]"
                     /db_xref="CDD:99777"
     misc_feature    order(332479..332481,332485..332487,332491..332493,
                     332584..332592,332599..332601,332608..332610)
                     /gene="yahA"
                     /locus_tag="b0315"
                     /gene_synonym="ECK0313; JW0307"
                     /note="dimerization interface [polypeptide binding]; other
                     site"
                     /db_xref="CDD:99777"
     misc_feature    332701..333414
                     /gene="yahA"
                     /locus_tag="b0315"
                     /gene_synonym="ECK0313; JW0307"
                     /note="EAL domain. This domain is found in diverse
                     bacterial signaling proteins. It is called EAL after its
                     conserved residues and is also known as domain of unknown
                     function 2 (DUF2).  The EAL domain has been shown to
                     stimulate degradation of a second...; Region: EAL;
                     cd01948"
                     /db_xref="CDD:238923"
     gene            complement(333501..334433)
                     /gene="yahB"
                     /locus_tag="b0316"
                     /gene_synonym="ECK0314; JW0308"
                     /db_xref="EcoGene:EG13586"
                     /db_xref="GeneID:945278"
     CDS             complement(333501..334433)
                     /gene="yahB"
                     /locus_tag="b0316"
                     /gene_synonym="ECK0314; JW0308"
                     /function="putative regulator; Not classified"
                     /GO_function="GO:0016563 - transcription activator
                     activity"
                     /GO_function="GO:0016564 - transcription repressor
                     activity"
                     /GO_process="GO:0006350 - transcription"
                     /note="putative transcriptional regulator LYSR-type"
                     /codon_start=1
                     /transl_table=11
                     /product="putative DNA-bindng transcriptional regulator"
                     /protein_id="NP_414850.1"
                     /db_xref="GI:16128301"
                     /db_xref="ASAP:ABE-0001088"
                     /db_xref="UniProtKB/Swiss-Prot:P77700"
                     /db_xref="EcoGene:EG13586"
                     /db_xref="GeneID:945278"
                     /translation="MNSIFTEENLLAFTTAARFGSFSKAAEELGLTTSAISYTIKRME
                     TGLDVVLFTRSTRSIELTESGRYFFRKATDLLNDFYAIKRRIDTISQGIEARVRICIN
                     QLLYTPKHTARLLQVLKKQFPTCQITVTTEVYNGVWDAIINNQANIAIGAPDTLLDGG
                     GIDYTEIGAIRWAFAIAPDHPLAFVPEPIAESQLRLYPNIMVEDTAHTINKKVGWLLH
                     GQESILVPDFNTKCQCQILGEGIGFLPDYMVREAMTQSLLVTRQIHNPRQDSRMLLAT
                     QHSATGQVTQWIKKQFAPNGILTGIYQDLLHREN"
     misc_feature    complement(333555..334421)
                     /gene="yahB"
                     /locus_tag="b0316"
                     /gene_synonym="ECK0314; JW0308"
                     /note="DNA-binding transcriptional activator AllS;
                     Provisional; Region: PRK10094"
                     /db_xref="CDD:182237"
     misc_feature    complement(334236..334406)
                     /gene="yahB"
                     /locus_tag="b0316"
                     /gene_synonym="ECK0314; JW0308"
                     /note="Bacterial regulatory helix-turn-helix protein, lysR
                     family; Region: HTH_1; pfam00126"
                     /db_xref="CDD:249610"
     misc_feature    complement(333573..334142)
                     /gene="yahB"
                     /locus_tag="b0316"
                     /gene_synonym="ECK0314; JW0308"
                     /note="The substrate binding domain of LysR-type
                     transcriptional regulators (LTTRs), a member of the type 2
                     periplasmic binding fold protein superfamily; Region:
                     PBP2_LTTR_substrate; cl11398"
                     /db_xref="CDD:264351"
     misc_feature    complement(order(333723..333728,333732..333737,
                     333753..333770,334041..334061,334065..334067,
                     334077..334082,334086..334091))
                     /gene="yahB"
                     /locus_tag="b0316"
                     /gene_synonym="ECK0314; JW0308"
                     /note="dimerization interface [polypeptide binding]; other
                     site"
                     /db_xref="CDD:176102"
     gene            complement(334525..335022)
                     /gene="yahC"
                     /locus_tag="b0317"
                     /gene_synonym="ECK0315; JW0309"
                     /db_xref="EcoGene:EG13587"
                     /db_xref="GeneID:947337"
     CDS             complement(334525..335022)
                     /gene="yahC"
                     /locus_tag="b0317"
                     /gene_synonym="ECK0315; JW0309"
                     /codon_start=1
                     /transl_table=11
                     /product="putative inner membrane protein"
                     /protein_id="NP_414851.1"
                     /db_xref="GI:16128302"
                     /db_xref="ASAP:ABE-0001091"
                     /db_xref="UniProtKB/Swiss-Prot:P77219"
                     /db_xref="EcoGene:EG13587"
                     /db_xref="GeneID:947337"
                     /translation="MNGLTATGVTVGICAGLWQLVSSHVGLSQGWELLGTIGFVAFCS
                     FYAAGGGKSGFIRSLAVNYSGMVWAFFAALTAGWLASVSGLSAFWASVITTVPFSAVV
                     VWQGRFWLLSFIPGGFLGMTLFFASGMNWTVTLLGFLAGNCVGVISEYGGQKLSEATT
                     KRDGY"
     misc_feature    complement(334552..334998)
                     /gene="yahC"
                     /locus_tag="b0317"
                     /gene_synonym="ECK0315; JW0309"
                     /note="Protein of unknown function (DUF1097); Region:
                     DUF1097; pfam06496"
                     /db_xref="CDD:253770"
     gene            335280..335885
                     /gene="yahD"
                     /locus_tag="b0318"
                     /gene_synonym="ECK0316; JW0310"
                     /db_xref="EcoGene:EG13588"
                     /db_xref="GeneID:947681"
     CDS             335280..335885
                     /gene="yahD"
                     /locus_tag="b0318"
                     /gene_synonym="ECK0316; JW0310"
                     /function="putative regulator; Not classified"
                     /note="putative transcription factor"
                     /codon_start=1
                     /transl_table=11
                     /product="ankyrin repeat protein"
                     /protein_id="NP_414852.1"
                     /db_xref="GI:16128303"
                     /db_xref="ASAP:ABE-0001095"
                     /db_xref="UniProtKB/Swiss-Prot:P77736"
                     /db_xref="EcoGene:EG13588"
                     /db_xref="GeneID:947681"
                     /translation="MSIKNLPADYLLAAQQGDIDKVKTCLALGVDINTCDRQGKTAIT
                     LASLYQQYACVQALIDAGADINKQDHTCLNPFLISCLNDDLTLLRIILPAKPDLNCVT
                     RFGGVGLTPACEKGHLSIVKELLAHTEINVNQTNHVGWTPLLEAIVLNDGGIKQQAIV
                     QLLLEHGASPHLTDKYGKTPLELARERGFEEIAQLLIAAGA"
     misc_feature    335313..335576
                     /gene="yahD"
                     /locus_tag="b0318"
                     /gene_synonym="ECK0316; JW0310"
                     /note="Ankyrin repeats (3 copies); Region: Ank_2;
                     pfam12796"
                     /db_xref="CDD:257303"
     misc_feature    335376..335870
                     /gene="yahD"
                     /locus_tag="b0318"
                     /gene_synonym="ECK0316; JW0310"
                     /note="ankyrin repeats;  ankyrin repeats mediate
                     protein-protein interactions in very diverse families of
                     proteins. The number of ANK repeats in a protein can range
                     from 2 to over 20 (ankyrins, for example). ANK repeats may
                     occur in combinations with other...; Region: ANK; cd00204"
                     /db_xref="CDD:238125"
     misc_feature    335505..335801
                     /gene="yahD"
                     /locus_tag="b0318"
                     /gene_synonym="ECK0316; JW0310"
                     /note="Ankyrin repeats (3 copies); Region: Ank_2;
                     pfam12796"
                     /db_xref="CDD:257303"
     gene            335925..336788
                     /gene="yahE"
                     /locus_tag="b0319"
                     /gene_synonym="ECK0317; JW0311"
                     /db_xref="EcoGene:EG13589"
                     /db_xref="GeneID:947134"
     CDS             335925..336788
                     /gene="yahE"
                     /locus_tag="b0319"
                     /gene_synonym="ECK0317; JW0311"
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2877 family protein"
                     /protein_id="NP_414853.1"
                     /db_xref="GI:16128304"
                     /db_xref="ASAP:ABE-0001097"
                     /db_xref="UniProtKB/Swiss-Prot:P77297"
                     /db_xref="EcoGene:EG13589"
                     /db_xref="GeneID:947134"
                     /translation="MWALTADADFLAQRGQGQVEQVFARAVNIALPARQQLLTLLCEE
                     YDNAPNSCRLALTHFDDLFRHGDKVQFDDQGITVGQHLHIEMSRCRRWLSPTLQMTAV
                     NFHLIAWLQWHDIIHQHLGENETLFNYRGDNPFYQALNKELHIKRRAVIQAVNDKQNI
                     ASAVASMMGLGIGLTPSADDYLTGLALILFIPGHPAEKYKEEFYLGLQRGKNNTTLLS
                     AITLEAALQQRCRENIHRFIHNIIYDIPGNATQAIEKIKHIGSSSGCDMLYGMADGCA
                     LSQTYGGNYVS"
     misc_feature    336423..336755
                     /gene="yahE"
                     /locus_tag="b0319"
                     /gene_synonym="ECK0317; JW0311"
                     /note="Protein of unknown function (DUF2877); Region:
                     DUF2877; pfam11392"
                     /db_xref="CDD:256444"
     gene            336778..338325
                     /gene="yahF"
                     /locus_tag="b0320"
                     /gene_synonym="ECK0318; JW0312"
                     /db_xref="EcoGene:EG13590"
                     /db_xref="GeneID:947298"
     CDS             336778..338325
                     /gene="yahF"
                     /locus_tag="b0320"
                     /gene_synonym="ECK0318; JW0312"
                     /function="putative enzyme; Not classified"
                     /note="putative oxidoreductase subunit"
                     /codon_start=1
                     /transl_table=11
                     /product="putative NAD(P)-binding succinyl-CoA synthase"
                     /protein_id="NP_414854.1"
                     /db_xref="GI:16128305"
                     /db_xref="ASAP:ABE-0001099"
                     /db_xref="UniProtKB/Swiss-Prot:P77187"
                     /db_xref="EcoGene:EG13590"
                     /db_xref="GeneID:947298"
                     /translation="MSVKIVIKPNTYFDSVSLMSISTRANKLDGVEQAFVAMATEMNK
                     GVLKNLGLLTPELEQAKNGDLMIVINGKSGADNEQLLVEIEELFNTKAQSGSHEARYA
                     TIGSAKKHIPESNLAVISVNGLFAAREARQALQNDLNVMLFSDNVSVEDELALKQLAH
                     EKGLLMMGPDCGTAIINGAALCFGNAVRRGNIGIVGASGTGSQELSVRIHEFGGGVSQ
                     LIGTGGRDLSEKIGGLMMLDAIGMLENDPQTEIIALISKPPAPAVARKVLERARACRK
                     PVVVCFLDRGETPVDEQGLQFARGTKEAALKAVMLSGVKQENLDLHTLNQPLIADVRA
                     RLQPQQKYIRGLFCGGTLCDETMFAVMEKHGDVYSNIQPDPEFRLKDINRSIKHTFLD
                     FGDDDFTNGKPHPMIDPTNRISRLIEEARDPEVAVIVMDFVLGFGSHEDPVGSTIETI
                     KEAKAIAAAEGRELIILAYVLGTDLDTPSLEQQSQMLLDAGVILASSSTNTGLLAREF
                     ICKGEEA"
     misc_feature    336832..337893
                     /gene="yahF"
                     /locus_tag="b0320"
                     /gene_synonym="ECK0318; JW0312"
                     /note="Succinyl-CoA synthetase, alpha subunit [Energy
                     production and conversion]; Region: SucD; COG0074"
                     /db_xref="CDD:223152"
     misc_feature    337153..>337341
                     /gene="yahF"
                     /locus_tag="b0320"
                     /gene_synonym="ECK0318; JW0312"
                     /note="Type 1 periplasmic binding fold superfamily;
                     Region: Periplasmic_Binding_Protein_Type_1; cl10011"
                     /db_xref="CDD:263940"
     misc_feature    337336..337626
                     /gene="yahF"
                     /locus_tag="b0320"
                     /gene_synonym="ECK0318; JW0312"
                     /note="CoA binding domain; Region: CoA_binding; pfam02629"
                     /db_xref="CDD:251432"
     misc_feature    337813..338292
                     /gene="yahF"
                     /locus_tag="b0320"
                     /gene_synonym="ECK0318; JW0312"
                     /note="CoA-ligase; Region: Ligase_CoA; pfam00549"
                     /db_xref="CDD:249950"
     gene            338325..339743
                     /gene="yahG"
                     /locus_tag="b0321"
                     /gene_synonym="ECK0319; JW0313"
                     /db_xref="EcoGene:EG13591"
                     /db_xref="GeneID:945379"
     CDS             338325..339743
                     /gene="yahG"
                     /locus_tag="b0321"
                     /gene_synonym="ECK0319; JW0313"
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1116 family protein"
                     /protein_id="NP_414855.1"
                     /db_xref="GI:16128306"
                     /db_xref="ASAP:ABE-0001101"
                     /db_xref="UniProtKB/Swiss-Prot:P77221"
                     /db_xref="EcoGene:EG13591"
                     /db_xref="GeneID:945379"
                     /translation="MSQSLFSQPLNVINVGIAMFSDDLKKQHVEVTQLDWTPPGQGNM
                     QVVQALDNIADSPLADKIAAANQQALERIIQSHPVLIGFDQAINVVPGMTAKTILHAG
                     PPITWEKMCGAMKGAVTGALVFEGLAKDLDEAAELAASGEITFSPCHEHDCVGSMAGV
                     TSASMFMHIVKNKTYGNIAYTNMSEQMAKILRMGANDQSVIDRLNWMRDVQGPILRDA
                     MKIIGEIDLRLMLAQALHMGDECHNRNNAGTTLLIQALTPGIIQAGYSVEQQREVFEF
                     VASSDYFSGPTWMAMCKAAMDAAHGIEYSTVVTTMARNGVEFGLRVSGLPGQWFTGPA
                     QQVIGPMFAGYKPEDSGLDIGDSAITETYGIGGFAMATAPAIVALVGGTVEEAIDFSR
                     QMREITLGENPNVTIPLLGFMGVPSAIDITRVGSSGILPVINTAIAHKDAGVGMIGAG
                     IVHPPFACFEKAILGWCERYGV"
     misc_feature    338751..339398
                     /gene="yahG"
                     /locus_tag="b0321"
                     /gene_synonym="ECK0319; JW0313"
                     /note="Protein of unknown function (DUF1116); Region:
                     DUF1116; pfam06545"
                     /db_xref="CDD:148259"
     repeat_region   339757..340114
                     /note="REP23 (repetitive extragenic palindromic) element;
                     contains 8 REP sequences"
     gene            340165..341115
                     /gene="yahI"
                     /locus_tag="b0323"
                     /gene_synonym="ECK0321; JW0315"
                     /db_xref="EcoGene:EG13593"
                     /db_xref="GeneID:944984"
     CDS             340165..341115
                     /gene="yahI"
                     /locus_tag="b0323"
                     /gene_synonym="ECK0321; JW0315"
                     /function="putative enzyme; Not classified"
                     /GO_process="GO:0006526 - arginine biosynthetic process"
                     /GO_process="GO:0006221 - pyrimidine nucleotide
                     biosynthetic process"
                     /note="putative kinase"
                     /codon_start=1
                     /transl_table=11
                     /product="carbamate kinase-like protein"
                     /protein_id="NP_414857.1"
                     /db_xref="GI:16128308"
                     /db_xref="ASAP:ABE-0001107"
                     /db_xref="UniProtKB/Swiss-Prot:P77624"
                     /db_xref="EcoGene:EG13593"
                     /db_xref="GeneID:944984"
                     /translation="MKELVVVAIGGNSIIKDNASQSIEHQAEAVKAVADTVLEMLASD
                     YDIVLTHGNGPQVGLDLRRAEIAHKREGLPLTPLANCVADTQGGIGYLIQQALNNRLA
                     RHGEKKAVTVVTQVEVDKNDPGFAHPTKPIGAFFSDSQRDELQKANPDWCFVEDAGRG
                     YRRVVASPEPKRIVEAPAIKALIQQGFVVIGAGGGGIPVVRTDAGDYQSVDAVIDKDL
                     STALLAREIHADILVITTGVEKVCIHFGKPQQQALDRVDIATMTRYMQEGHFPPGSML
                     PKIIASLTFLEQGGKEVIITTPECLPAALRGETGTHIIKT"
     misc_feature    340174..341106
                     /gene="yahI"
                     /locus_tag="b0323"
                     /gene_synonym="ECK0321; JW0315"
                     /note="AAK_CK: Carbamate kinase (CK) catalyzes both the
                     ATP-phosphorylation of carbamate and carbamoyl phosphate
                     (CP) utilization with the production of ATP from ADP and
                     CP. Both CK (this CD) and nonhomologous CP synthetase
                     synthesize carbamoyl phosphate, an...; Region: AAK_CK;
                     cd04235"
                     /db_xref="CDD:239768"
     misc_feature    order(340186..340188,340192..340197,340318..340326,
                     340552..340554,340807..340815)
                     /gene="yahI"
                     /locus_tag="b0323"
                     /gene_synonym="ECK0321; JW0315"
                     /note="putative substrate binding site [chemical binding];
                     other site"
                     /db_xref="CDD:239768"
     misc_feature    order(340195..340197,340870..340875,340888..340890,
                     340897..340899,340972..340974,340984..340989,
                     340996..340998)
                     /gene="yahI"
                     /locus_tag="b0323"
                     /gene_synonym="ECK0321; JW0315"
                     /note="nucleotide binding site [chemical binding]; other
                     site"
                     /db_xref="CDD:239768"
     misc_feature    order(340195..340197,340870..340875,340888..340890,
                     340897..340899,340972..340974,340984..340989,
                     340996..340998)
                     /gene="yahI"
                     /locus_tag="b0323"
                     /gene_synonym="ECK0321; JW0315"
                     /note="nucleotide binding site [chemical binding]; other
                     site"
                     /db_xref="CDD:239768"
     misc_feature    order(340348..340350,340390..340392,340399..340404,
                     340411..340413,340423..340428,340435..340437,
                     340444..340449,340459..340461,340495..340503,
                     340507..340509,340687..340689,340696..340698,
                     340783..340785,340789..340791)
                     /gene="yahI"
                     /locus_tag="b0323"
                     /gene_synonym="ECK0321; JW0315"
                     /note="homodimer interface [polypeptide binding]; other
                     site"
                     /db_xref="CDD:239768"
     gene            341125..342507
                     /gene="yahJ"
                     /locus_tag="b0324"
                     /gene_synonym="ECK0322; JW0316"
                     /db_xref="EcoGene:EG13594"
                     /db_xref="GeneID:944976"
     CDS             341125..342507
                     /gene="yahJ"
                     /locus_tag="b0324"
                     /gene_synonym="ECK0322; JW0316"
                     /function="putative enzyme; Not classified"
                     /GO_process="GO:0009310 - amine catabolic process"
                     /note="putative deaminase"
                     /codon_start=1
                     /transl_table=11
                     /product="putative metallo-dependent hydrolase domain
                     deaminase"
                     /protein_id="NP_414858.1"
                     /db_xref="GI:16128309"
                     /db_xref="ASAP:ABE-0001109"
                     /db_xref="UniProtKB/Swiss-Prot:P77554"
                     /db_xref="EcoGene:EG13594"
                     /db_xref="GeneID:944976"
                     /translation="MKESNSRREFLSQSGKMVTAAALFGTSVPLAHAAVAGTLNCEAN
                     NTMKITDPHYYLDNVLLETGFDYENGVAVQTRTARQTVEIQDGKIVALRENKLHPDAT
                     LPHYDAGGKLMLPTTRDMHIHLDKTFYGGPWRSLNRPAGTTIQDMIKLEQKMLPELQP
                     YTQERAEKLIDLLQSKGTTIARSHCNIEPVSGLKNLQNLQAVLARRQAGFECEIVAFP
                     QHGLLLSKSEPLMREAMQAGAHYVGGLDPTSVDGAMEKSLDTMFQIALDYDKGVDIHL
                     HETTPAGVAAINYMVETVEKTPQLKGKLTISHAFALATLNEQQVDELANRMVVQQISI
                     ASTVPIGTLHMPLKQLHDKGVKVMTGTDSVIDHWSPYGLGDMLEKANLYAQLYIRPNE
                     QNLSRSLFLATGDVLPLNEKGERVWPKAQDDASFVLVDASCSAEAVARISPRTATFHK
                     GQLVWGSVAG"
     misc_feature    341287..342486
                     /gene="yahJ"
                     /locus_tag="b0324"
                     /gene_synonym="ECK0322; JW0316"
                     /note="Bacterial cytosine deaminase and related
                     metal-dependent hydrolases. Cytosine deaminases (CDs)
                     catalyze the deamination of cytosine, producing uracil and
                     ammonia. They play an important role in pyrimidine
                     salvage. CDs are present in prokaryotes and fungi; Region:
                     Bact_CD; cd01293"
                     /db_xref="CDD:238618"
     misc_feature    341356..342486
                     /gene="yahJ"
                     /locus_tag="b0324"
                     /gene_synonym="ECK0322; JW0316"
                     /note="cytosine deaminase; Provisional; Region: PRK05985"
                     /db_xref="CDD:180337"
     misc_feature    order(341485..341487,341491..341493,341947..341949,
                     341956..341958,342046..342048,342208..342210)
                     /gene="yahJ"
                     /locus_tag="b0324"
                     /gene_synonym="ECK0322; JW0316"
                     /note="active site"
                     /db_xref="CDD:238618"
     gene            342884..343933
                     /gene="yahK"
                     /locus_tag="b0325"
                     /gene_synonym="ECK0323; JW0317"
                     /db_xref="EcoGene:EG13595"
                     /db_xref="GeneID:944975"
     CDS             342884..343933
                     /gene="yahK"
                     /locus_tag="b0325"
                     /gene_synonym="ECK0323; JW0317"
                     /function="enzyme; Degradation of small molecules: Carbon
                     compounds"
                     /note="putative oxidoreductase"
                     /codon_start=1
                     /transl_table=11
                     /product="broad specificity NADPH-dependent aldehyde
                     reductase, Zn-containing"
                     /protein_id="NP_414859.1"
                     /db_xref="GI:16128310"
                     /db_xref="ASAP:ABE-0001113"
                     /db_xref="UniProtKB/Swiss-Prot:P75691"
                     /db_xref="EcoGene:EG13595"
                     /db_xref="GeneID:944975"
                     /translation="MKIKAVGAYSAKQPLEPMDITRREPGPNDVKIEIAYCGVCHSDL
                     HQVRSEWAGTVYPCVPGHEIVGRVVAVGDQVEKYAPGDLVGVGCIVDSCKHCEECEDG
                     LENYCDHMTGTYNSPTPDEPGHTLGGYSQQIVVHERYVLRIRHPQEQLAAVAPLLCAG
                     ITTYSPLRHWQAGPGKKVGVVGIGGLGHMGIKLAHAMGAHVVAFTTSEAKREAAKALG
                     ADEVVNSRNADEMAAHLKSFDFILNTVAAPHNLDDFTTLLKRDGTMTLVGAPATPHKS
                     PEVFNLIMKRRAIAGSMIGGIPETQEMLDFCAEHGIVADIEMIRADQINEAYERMLRG
                     DVKYRFVIDNRTLTD"
     misc_feature    342884..343921
                     /gene="yahK"
                     /locus_tag="b0325"
                     /gene_synonym="ECK0323; JW0317"
                     /note="Zn-dependent alcohol dehydrogenases [General
                     function prediction only]; Region: AdhP; COG1064"
                     /db_xref="CDD:223992"
     misc_feature    342893..343912
                     /gene="yahK"
                     /locus_tag="b0325"
                     /gene_synonym="ECK0323; JW0317"
                     /note="Cinnamyl alcohol dehydrogenases (CAD); Region:
                     CAD1; cd05283"
                     /db_xref="CDD:176186"
     misc_feature    order(343001..343009,343016..343018,343355..343357,
                     343367..343369,343427..343444,343496..343501,
                     343511..343513,343556..343558,343613..343618,
                     343622..343624,343682..343687,343757..343765)
                     /gene="yahK"
                     /locus_tag="b0325"
                     /gene_synonym="ECK0323; JW0317"
                     /note="putative NAD(P) binding site [chemical binding];
                     other site"
                     /db_xref="CDD:176186"
     misc_feature    order(343001..343003,343007..343009,343067..343069,
                     343145..343147,343355..343357,343763..343765)
                     /gene="yahK"
                     /locus_tag="b0325"
                     /gene_synonym="ECK0323; JW0317"
                     /note="putative substrate binding site [chemical binding];
                     other site"
                     /db_xref="CDD:176186"
     misc_feature    order(343001..343003,343067..343069,343355..343357)
                     /gene="yahK"
                     /locus_tag="b0325"
                     /gene_synonym="ECK0323; JW0317"
                     /note="catalytic Zn binding site [ion binding]; other
                     site"
                     /db_xref="CDD:176186"
     misc_feature    order(343160..343162,343169..343171,343178..343180,
                     343202..343204)
                     /gene="yahK"
                     /locus_tag="b0325"
                     /gene_synonym="ECK0323; JW0317"
                     /note="structural Zn binding site [ion binding]; other
                     site"
                     /db_xref="CDD:176186"
     misc_feature    order(343199..343201,343376..343378,343388..343390,
                     343664..343666,343679..343687,343691..343693,
                     343721..343723,343727..343732,343739..343762)
                     /gene="yahK"
                     /locus_tag="b0325"
                     /gene_synonym="ECK0323; JW0317"
                     /note="dimer interface [polypeptide binding]; other site"
                     /db_xref="CDD:176186"
     gene            344176..344991
                     /gene="yahL"
                     /locus_tag="b0326"
                     /gene_synonym="ECK0324; JW0318"
                     /db_xref="EcoGene:EG13596"
                     /db_xref="GeneID:944970"
     CDS             344176..344991
                     /gene="yahL"
                     /locus_tag="b0326"
                     /gene_synonym="ECK0324; JW0318"
                     /codon_start=1
                     /transl_table=11
                     /product="uncharacterized protein"
                     /protein_id="NP_414860.1"
                     /db_xref="GI:16128311"
                     /db_xref="ASAP:ABE-0001117"
                     /db_xref="UniProtKB/Swiss-Prot:P77393"
                     /db_xref="EcoGene:EG13596"
                     /db_xref="GeneID:944970"
                     /translation="MISLKAPHNNLMPYTQQSILNTVKNNQLPEDIKSSLVSCVDIFK
                     VLIKQYYDYPYDCRDDLVDDDKLIHLMAAVRDCEWSDDNALTINVQFNDFPGFYDWMD
                     YPDHPVKFVFHILENQKGTVWVYDQDDAFLDIKANVQAGRFTGLKKLVQFIDSVRTDC
                     KCILLEYHMPLLRIFPKGKECMHVEKWLREMSSIPETDAPIKQALAHGLLLHLKNIYP
                     VFPESLVMLLLSVLDVKTYRDDARLNEWISNRVQELGDRYYPVNKHVKIRYTL"
     gene            345404..345649
                     /gene="yahM"
                     /locus_tag="b0327"
                     /gene_synonym="ECK0325; JW5044"
                     /db_xref="EcoGene:EG13597"
                     /db_xref="GeneID:944969"
     CDS             345404..345649
                     /gene="yahM"
                     /locus_tag="b0327"
                     /gene_synonym="ECK0325; JW5044"
                     /codon_start=1
                     /transl_table=11
                     /product="uncharacterized protein"
                     /protein_id="NP_414861.2"
                     /db_xref="GI:90111114"
                     /db_xref="ASAP:ABE-0001120"
                     /db_xref="UniProtKB/Swiss-Prot:P75692"
                     /db_xref="EcoGene:EG13597"
                     /db_xref="GeneID:944969"
                     /translation="MAVQLFKTLLNQIPLLSSLQSGTLPLFGYSGWGRPMKKAHTGES
                     GLKWEAKDSSKLIGNKDHALRGLSSPMAVIRQIRLIT"
     gene            complement(345666..346337)
                     /gene="yahN"
                     /locus_tag="b0328"
                     /gene_synonym="ECK0326; JW0320"
                     /db_xref="EcoGene:EG13598"
                     /db_xref="GeneID:944968"
     CDS             complement(345666..346337)
                     /gene="yahN"
                     /locus_tag="b0328"
                     /gene_synonym="ECK0326; JW0320"
                     /function="transport; Not classified"
                     /note="putative cytochrome subunit of dehydrogenase"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid exporter for proline, lysine,
                     glutamate, homoserine"
                     /protein_id="NP_414862.1"
                     /db_xref="GI:16128313"
                     /db_xref="ASAP:ABE-0001122"
                     /db_xref="UniProtKB/Swiss-Prot:P75693"
                     /db_xref="EcoGene:EG13598"
                     /db_xref="GeneID:944968"
                     /translation="MMQLVHLFMDEITMDPLHAVYLTVGLFVITFFNPGANLFVVVQT
                     SLASGRRAGVLTGLGVALGDAFYSGLGLFGLATLITQCEEIFSLIRIVGGAYLLWFAW
                     CSMRRQSTPQMSTLQQPISAPWYVFFRRGLITDLSNPQTVLFFISIFSVTLNAETPTW
                     ARLMAWAGIVLASIIWRVFLSQAFSLPAVRRAYGRMQRVASRVIGAIIGVFALRLIYE
                     GVTQR"
     misc_feature    complement(345693..346241)
                     /gene="yahN"
                     /locus_tag="b0328"
                     /gene_synonym="ECK0326; JW0320"
                     /note="The Resistance to Homoserine/Threonine (RhtB)
                     Family protein; Region: 2A76; TIGR00949"
                     /db_xref="CDD:233204"
     STS             346455..347086
                     /standard_name="D14S163"
                     /db_xref="UniSTS:148387"
     gene            346484..346759
                     /gene="yahO"
                     /locus_tag="b0329"
                     /gene_synonym="ECK0327; JW0321"
                     /db_xref="EcoGene:EG13599"
                     /db_xref="GeneID:944985"
     CDS             346484..346759
                     /gene="yahO"
                     /locus_tag="b0329"
                     /gene_synonym="ECK0327; JW0321"
                     /codon_start=1
                     /transl_table=11
                     /product="periplasmic protein, function unknown, YhcN
                     family"
                     /protein_id="NP_414863.1"
                     /db_xref="GI:16128314"
                     /db_xref="ASAP:ABE-0001130"
                     /db_xref="UniProtKB/Swiss-Prot:P75694"
                     /db_xref="EcoGene:EG13599"
                     /db_xref="GeneID:944985"
                     /translation="MKIISKMLVGALALAVTNVYAAELMTKAEFEKVESQYEKIGDIS
                     TSNEMSTADAKEDLIKKADEKGADVLVLTSGQTDNKIHGTANIYKKK"
     misc_feature    346484..346756
                     /gene="yahO"
                     /locus_tag="b0329"
                     /gene_synonym="ECK0327; JW0321"
                     /note="hypothetical protein; Provisional; Region:
                     PRK09929"
                     /db_xref="CDD:182151"
     repeat_region   346824..346853
                     /note="REP24 (repetitive extragenic palindromic) element;
                     contains 1 REP sequences"
     gene            complement(346857..348443)
                     /gene="prpR"
                     /locus_tag="b0330"
                     /gene_synonym="ECK0328; JW0322; yahP"
                     /db_xref="EcoGene:EG13600"
                     /db_xref="GeneID:944987"
     CDS             complement(346857..348443)
                     /gene="prpR"
                     /locus_tag="b0330"
                     /gene_synonym="ECK0328; JW0322; yahP"
                     /function="regulator; Not classified"
                     /GO_component="GO:0005737 - cytoplasm"
                     /GO_function="GO:0016564 - transcription repressor
                     activity"
                     /GO_process="GO:0019395 - fatty acid oxidation"
                     /GO_process="GO:0006350 - transcription"
                     /note="regulator for prp operon"
                     /codon_start=1
                     /transl_table=11
                     /product="propionate catabolism operon regulatory protein"
                     /protein_id="NP_414864.1"
                     /db_xref="GI:16128315"
                     /db_xref="ASAP:ABE-0001133"
                     /db_xref="UniProtKB/Swiss-Prot:P77743"
                     /db_xref="EcoGene:EG13600"
                     /db_xref="GeneID:944987"
                     /translation="MAHPPRLNDDKPVIWTVSVTRLFELFRDISLEFDHLANITPIQL
                     GFEKAVTYIRKKLANERCDAIIAAGSNGAYLKSRLSVPVILIKPSGYDVLQALAKAGK
                     LTSSIGVVTYQETIPALVAFQKTFNLRLDQRSYITEEDARGQINELKANGTEAVVGAG
                     LITDLAEEAGMTGIFIYSAATVRQAFSDALDMTRMSLRHNTHDATRNALRTRYVLGDM
                     LGQSPQMEQVRQTILLYARSSAAVLIEGETGTGKELAAQAIHREYFARHDARQGKKSH
                     PFVAVNCGAIAESLLEAELFGYEEGAFTGSRRGGRAGLFEIAHGGTLFLDEIGEMPLP
                     LQTRLLRVLEEKEVTRVGGHQPVPVDVRVISATHCNLEEDMQQGRFRRDLFYRLSILR
                     LQLPPLRERVADILPLAESFLKVSLAALSAPFSAALRQGLQASETVLLHYDWPGNIRE
                     LRNMMERLALFLSVEPTPDLTPQFMQLLLPELARESAKTPAPRLLTPQQALEKFNGDK
                     TAAANYLGISRTTFWRRLKS"
     misc_feature    complement(346860..348443)
                     /gene="prpR"
                     /locus_tag="b0330"
                     /gene_synonym="ECK0328; JW0322; yahP"
                     /note="propionate catabolism operon regulatory protein
                     PrpR; Provisional; Region: PRK15424"
                     /db_xref="CDD:237963"
     misc_feature    complement(347859..348362)
                     /gene="prpR"
                     /locus_tag="b0330"
                     /gene_synonym="ECK0328; JW0322; yahP"
                     /note="Propionate catabolism activator; Region: PrpR_N;
                     pfam06506"
                     /db_xref="CDD:253773"
     misc_feature    complement(347253..347786)
                     /gene="prpR"
                     /locus_tag="b0330"
                     /gene_synonym="ECK0328; JW0322; yahP"
                     /note="The AAA+ (ATPases Associated with a wide variety of
                     cellular Activities) superfamily represents an ancient
                     group of ATPases belonging to the ASCE (for additional
                     strand, catalytic E) division of the P-loop NTPase fold.
                     The ASCE division also includes ABC; Region: AAA; cd00009"
                     /db_xref="CDD:99707"
     misc_feature    complement(347685..347708)
                     /gene="prpR"
                     /locus_tag="b0330"
                     /gene_synonym="ECK0328; JW0322; yahP"
                     /note="Walker A motif; other site"
                     /db_xref="CDD:99707"
     misc_feature    complement(order(347340..347342,347466..347468,
                     347682..347705))
                     /gene="prpR"
                     /locus_tag="b0330"
                     /gene_synonym="ECK0328; JW0322; yahP"
                     /note="ATP binding site [chemical binding]; other site"
                     /db_xref="CDD:99707"
     misc_feature    complement(347463..347480)
                     /gene="prpR"
                     /locus_tag="b0330"
                     /gene_synonym="ECK0328; JW0322; yahP"
                     /note="Walker B motif; other site"
                     /db_xref="CDD:99707"
     misc_feature    complement(347283..347285)
                     /gene="prpR"
                     /locus_tag="b0330"
                     /gene_synonym="ECK0328; JW0322; yahP"
                     /note="arginine finger; other site"
                     /db_xref="CDD:99707"
     misc_feature    complement(346863..>346952)
                     /gene="prpR"
                     /locus_tag="b0330"
                     /gene_synonym="ECK0328; JW0322; yahP"
                     /note="Bacterial regulatory protein, Fis family; Region:
                     HTH_8; pfam02954"
                     /db_xref="CDD:251640"
     gene            348682..349572
                     /gene="prpB"
                     /locus_tag="b0331"
                     /gene_synonym="ECK0329; JW0323; yahQ"
                     /db_xref="EcoGene:EG13601"
                     /db_xref="GeneID:944990"
     CDS             348682..349572
                     /gene="prpB"
                     /locus_tag="b0331"
                     /gene_synonym="ECK0329; JW0323; yahQ"
                     /EC_number="4.1.3.30"
                     /function="putative enzyme; Not classified"
                     /GO_component="GO:0005737 - cytoplasm"
                     /GO_process="GO:0019395 - fatty acid oxidation"
                     /note="putative phosphonomutase 2"
                     /codon_start=1
                     /transl_table=11
                     /product="2-methylisocitrate lyase"
                     /protein_id="NP_414865.1"
                     /db_xref="GI:16128316"
                     /db_xref="ASAP:ABE-0001138"
                     /db_xref="UniProtKB/Swiss-Prot:P77541"
                     /db_xref="EcoGene:EG13601"
                     /db_xref="GeneID:944990"
                     /translation="MSLHSPGKAFRAALTKENPLQIVGTINANHALLAQRAGYQAIYL
                     SGGGVAAGSLGLPDLGISTLDDVLTDIRRITDVCSLPLLVDADIGFGSSAFNVARTVK
                     SMIKAGAAGLHIEDQVGAKRCGHRPNKAIVSKEEMVDRIRAAVDAKTDPDFVIMARTD
                     ALAVEGLDAAIERAQAYVEAGAEMLFPEAITELAMYRQFADAVQVPILANITEFGATP
                     LFTTDELRSAHVAMALYPLSAFRAMNRAAEHVYNVLRQEGTQKSVIDTMQTRNELYES
                     INYYQYEEKLDNLFARSQVK"
     misc_feature    348709..349434
                     /gene="prpB"
                     /locus_tag="b0331"
                     /gene_synonym="ECK0329; JW0323; yahQ"
                     /note="Members of the ICL/PEPM enzyme family catalyze
                     either P-C or C-C bond formation/cleavage. Known members
                     are phosphoenolpyruvate mutase (PEPM), phosphonopyruvate
                     hydrolase (PPH), carboxyPEP mutase (CPEP mutase),
                     oxaloacetate hydrolase (OAH), isocitrate...; Region:
                     ICL_PEPM; cd00377"
                     /db_xref="CDD:119340"
     misc_feature    order(348715..348717,348736..348738,348742..348753,
                     348757..348771,348775..348780,348787..348789,
                     348793..348801,348820..348822,348832..348834,
                     348838..348840,348847..348852,348859..348870,
                     348874..348879,348886..348891,348895..348900,
                     348907..348912,348952..348954,348973..348978,
                     348988..348990,348997..348999,349084..349089,
                     349096..349098,349105..349110,349117..349119,
                     349405..349413,349417..349425,349429..349434)
                     /gene="prpB"
                     /locus_tag="b0331"
                     /gene_synonym="ECK0329; JW0323; yahQ"
                     /note="tetramer interface [polypeptide binding]; other
                     site"
                     /db_xref="CDD:119340"
     misc_feature    order(348808..348810,348814..348822,348853..348855,
                     348934..348936,348940..348942,349024..349026,
                     349153..349155,349243..349245,349309..349311,
                     349315..349317,349387..349389)
                     /gene="prpB"
                     /locus_tag="b0331"
                     /gene_synonym="ECK0329; JW0323; yahQ"
                     /note="active site"
                     /db_xref="CDD:119340"
     misc_feature    order(348853..348855,348934..348936,348940..348942,
                     349024..349026)
                     /gene="prpB"
                     /locus_tag="b0331"
                     /gene_synonym="ECK0329; JW0323; yahQ"
                     /note="Mg2+/Mn2+ binding site [ion binding]; other site"
                     /db_xref="CDD:119340"
     repeat_region   349605..349969
                     /note="REP25 (repetitive extragenic palindromic) element;
                     contains 8 REP sequences"
     gene            350012..351181
                     /gene="prpC"
                     /locus_tag="b0333"
                     /gene_synonym="ECK0330; JW0324; yahS; yzzD"
                     /db_xref="EcoGene:EG11756"
                     /db_xref="GeneID:947528"
     CDS             350012..351181
                     /gene="prpC"
                     /locus_tag="b0333"
                     /gene_synonym="ECK0330; JW0324; yahS; yzzD"
                     /EC_number="2.3.3.1"
                     /function="putative enzyme; Not classified"
                     /GO_component="GO:0005737 - cytoplasm"
                     /GO_process="GO:0019395 - fatty acid oxidation"
                     /note="putative citrate synthase; propionate metabolism?"
                     /codon_start=1
                     /transl_table=11
                     /product="2-methylcitrate synthase"
                     /protein_id="NP_414867.1"
                     /db_xref="GI:16128318"
                     /db_xref="ASAP:ABE-0001148"
                     /db_xref="UniProtKB/Swiss-Prot:P31660"
                     /db_xref="EcoGene:EG11756"
                     /db_xref="GeneID:947528"
                     /translation="MSDTTILQNSTHVIKPKKSVALSGVPAGNTALCTVGKSGNDLHY
                     RGYDILDLAKHCEFEEVAHLLIHGKLPTRDELAAYKTKLKALRGLPANVRTVLEALPA
                     ASHPMDVMRTGVSALGCTLPEKEGHTVSGARDIADKLLASLSSILLYWYHYSHNGERI
                     QPETDDDSIGGHFLHLLHGEKPSQSWEKAMHISLVLYAEHEFNASTFTSRVIAGTGSD
                     MYSAIIGAIGALRGPKHGGANEVSLEIQQRYETPDEAEADIRKRVENKEVVIGFGHPV
                     YTIADPRHQVIKRVAKQLSQEGGSLKMYNIADRLETVMWESKKMFPNLDWFSAVSYNM
                     MGVPTEMFTPLFVIARVTGWAAHIIEQRQDNKIIRPSANYVGPEDRPFVALDKRQ"
     misc_feature    350039..351175
                     /gene="prpC"
                     /locus_tag="b0333"
                     /gene_synonym="ECK0330; JW0324; yahS; yzzD"
                     /note="Citrate synthase [Energy production and
                     conversion]; Region: GltA; COG0372"
                     /db_xref="CDD:223449"
     misc_feature    350069..351166
                     /gene="prpC"
                     /locus_tag="b0333"
                     /gene_synonym="ECK0330; JW0324; yahS; yzzD"
                     /note="Subgroup of Escherichia coli (Ec) 2-methylcitrate
                     synthase (2MCS)_like. 2MCS catalyzes the condensation of
                     propionyl-coenzyme A (PrCoA) and oxalacetate (OAA) to form
                     2-methylcitrate and coenzyme A (CoA) during propionate
                     metabolism. Citrate synthase (CS)...; Region:
                     Ec2MCS_like_1; cd06117"
                     /db_xref="CDD:99870"
     misc_feature    order(350069..350077,350084..350098,350282..350287,
                     350294..350299,350321..350323,350333..350335,
                     350345..350347,350354..350356,350498..350500,
                     350609..350623,350630..350635,350645..350647,
                     350654..350665,350672..350674,350693..350698,
                     350702..350713,350834..350836,351107..351139)
                     /gene="prpC"
                     /locus_tag="b0333"
                     /gene_synonym="ECK0330; JW0324; yahS; yzzD"
                     /note="dimer interface [polypeptide binding]; other site"
                     /db_xref="CDD:99870"
     misc_feature    order(350078..350080,350609..350611,350618..350620,
                     350711..350719,350723..350725,350732..350734,
                     350813..350836,350843..350845,350858..350860,
                     350963..350965,350969..350971,350978..350980,
                     350984..350986,351047..351049,351059..351061,
                     351107..351109,351116..351118)
                     /gene="prpC"
                     /locus_tag="b0333"
                     /gene_synonym="ECK0330; JW0324; yahS; yzzD"
                     /note="active site"
                     /db_xref="CDD:99870"
     misc_feature    order(350078..350080,350609..350611,350618..350620,
                     350711..350716,350813..350818,350822..350836,
                     350858..350860,350978..350980,351059..351061)
                     /gene="prpC"
                     /locus_tag="b0333"
                     /gene_synonym="ECK0330; JW0324; yahS; yzzD"
                     /note="citrylCoA binding site [chemical binding]; other
                     site"
                     /db_xref="CDD:99870"
     misc_feature    order(350609..350611,350618..350620,350714..350719,
                     350831..350833,350858..350860,350984..350986,
                     351047..351049,351059..351061,351116..351118)
                     /gene="prpC"
                     /locus_tag="b0333"
                     /gene_synonym="ECK0330; JW0324; yahS; yzzD"
                     /note="oxalacetate/citrate binding site [chemical
                     binding]; other site"
                     /db_xref="CDD:99870"
     misc_feature    order(350711..350716,350723..350725,350732..350734,
                     350813..350830,350834..350836,350843..350845,
                     350963..350965,350969..350971,350978..350980,
                     350984..350986,351107..351109)
                     /gene="prpC"
                     /locus_tag="b0333"
                     /gene_synonym="ECK0330; JW0324; yahS; yzzD"
                     /note="coenzyme A binding site [chemical binding]; other
                     site"
                     /db_xref="CDD:99870"
     misc_feature    order(350714..350716,350831..350833,350984..350986)
                     /gene="prpC"
                     /locus_tag="b0333"
                     /gene_synonym="ECK0330; JW0324; yahS; yzzD"
                     /note="catalytic triad [active]"
                     /db_xref="CDD:99870"
     gene            351215..352666
                     /gene="prpD"
                     /locus_tag="b0334"
                     /gene_synonym="acnC; ECK0331; JW0325; yahT"
                     /db_xref="EcoGene:EG13603"
                     /db_xref="GeneID:945931"
     CDS             351215..352666
                     /gene="prpD"
                     /locus_tag="b0334"
                     /gene_synonym="acnC; ECK0331; JW0325; yahT"
                     /EC_number="4.2.1.79"
                     /GO_process="GO:0016052 - carbohydrate catabolic process"
                     /codon_start=1
                     /transl_table=11
                     /product="2-methylcitrate dehydratase"
                     /protein_id="NP_414868.1"
                     /db_xref="GI:16128319"
                     /db_xref="ASAP:ABE-0001152"
                     /db_xref="UniProtKB/Swiss-Prot:P77243"
                     /db_xref="EcoGene:EG13603"
                     /db_xref="GeneID:945931"
                     /translation="MSAQINNIRPEFDREIVDIVDYVMNYEISSKVAYDTAHYCLLDT
                     LGCGLEALEYPACKKLLGPIVPGTVVPNGVRVPGTQFQLDPVQAAFNIGAMIRWLDFN
                     DTWLAAEWGHPSDNLGGILATADWLSRNAVASGKAPLTMKQVLTAMIKAHEIQGCIAL
                     ENSFNRVGLDHVLLVKVASTAVVAEMLGLTREEILNAVSLAWVDGQSLRTYRHAPNTG
                     TRKSWAAGDATSRAVRLALMAKTGEMGYPSALTAPVWGFYDVSFKGESFRFQRPYGSY
                     VMENVLFKISFPAEFHSQTAVEAAMTLYEQMQAAGKTAADIEKVTIRTHEACIRIIDK
                     KGPLNNPADRDHCIQYMVAIPLLFGRLTAADYEDNVAQDKRIDALREKINCFEDPAFT
                     ADYHDPEKRAIANAITLEFTDGTRFEEVVVEYPIGHARRRQDGIPKLVDKFKINLARQ
                     FPTRQQQRILEVSLDRARLEQMPVNEYLDLYVI"
     misc_feature    351215..352663
                     /gene="prpD"
                     /locus_tag="b0334"
                     /gene_synonym="acnC; ECK0331; JW0325; yahT"
                     /note="2-methylcitrate dehydratase; Provisional; Region:
                     prpD; PRK09425"
                     /db_xref="CDD:181845"
     gene            352706..354592
                     /gene="prpE"
                     /locus_tag="b0335"
                     /gene_synonym="ECK0332; JW0326; yahU"
                     /db_xref="EcoGene:EG13604"
                     /db_xref="GeneID:946891"
     CDS             352706..354592
                     /gene="prpE"
                     /locus_tag="b0335"
                     /gene_synonym="ECK0332; JW0326; yahU"
                     /function="putative enzyme; Not classified"
                     /GO_component="GO:0005737 - cytoplasm"
                     /GO_process="GO:0019395 - fatty acid oxidation"
                     /note="putative propionyl-CoA synthetase"
                     /codon_start=1
                     /transl_table=11
                     /product="propionate--CoA ligase"
                     /protein_id="NP_414869.1"
                     /db_xref="GI:16128320"
                     /db_xref="ASAP:ABE-0001154"
                     /db_xref="UniProtKB/Swiss-Prot:P77495"
                     /db_xref="EcoGene:EG13604"
                     /db_xref="GeneID:946891"
                     /translation="MSFSEFYQRSINEPEQFWAEQARRIDWQTPFTQTLDHSNPPFAR
                     WFCEGRTNLCHNAIDRWLEKQPEALALIAVSSETEEERTFTFRQLHDEVNAVASMLRS
                     LGVQRGDRVLVYMPMIAEAHITLLACARIGAIHSVVFGGFASHSVAARIDDAKPVLIV
                     SADAGARGGKIIPYKKLLDDAISQAQHQPRHVLLVDRGLAKMARVSGRDVDFASLRHQ
                     HIGARVPVAWLESNETSCILYTSGTTGKPKGVQRDVGGYAVALATSMDTIFGGKAGSV
                     FFCASDIGWVVGHSYIVYAPLLAGMATIVYEGLPTWPDCGVWWTIVEKYQVSRMFSAP
                     TAIRVLKKFPTAEIRKHDLSSLEVLYLAGEPLDEPTASWVSNTLDVPVIDNYWQTESG
                     WPIMAIARGLDDRPTRLGSPGVPMYGYNVQLLNEVTGEPCGVNEKGMLVVEGPLPPGC
                     IQTIWGDDGRFVKTYWSLFSRPVYATFDWGIRDADGYHFILGRTDDVINVAGHRLGTR
                     EIEESISSHPGVAEVAVVGVKDALKGQVAVAFVIPKESDSLEDRDVAHSQEKAIMALV
                     DSQIGNFGRPAHVWFVSQLPKTRSGKMLRRTIQAICEGRDPGDLTTIDDPASLDQIRQ
                     AMEE"
     misc_feature    352706..354589
                     /gene="prpE"
                     /locus_tag="b0335"
                     /gene_synonym="ECK0332; JW0326; yahU"
                     /note="propionyl-CoA synthetase; Provisional; Region:
                     prpE; PRK10524"
                     /db_xref="CDD:182517"
     misc_feature    352739..354571
                     /gene="prpE"
                     /locus_tag="b0335"
                     /gene_synonym="ECK0332; JW0326; yahU"
                     /note="Propionyl-CoA synthetase (PrpE); Region: PrpE;
                     cd05967"
                     /db_xref="CDD:213314"
     misc_feature    order(353414..353416,353423..353440,353444..353449)
                     /gene="prpE"
                     /locus_tag="b0335"
                     /gene_synonym="ECK0332; JW0326; yahU"
                     /note="acyl-activating enzyme (AAE) consensus motif; other
                     site"
                     /db_xref="CDD:213314"
     misc_feature    order(353423..353425,353789..353794,353855..353872,
                     354137..354139,354173..354175,354182..354184,
                     354215..354217,354479..354481)
                     /gene="prpE"
                     /locus_tag="b0335"
                     /gene_synonym="ECK0332; JW0326; yahU"
                     /note="putative AMP binding site [chemical binding]; other
                     site"
                     /db_xref="CDD:213314"
     misc_feature    order(353423..353425,353546..353551,353702..353704,
                     353708..353713,353720..353722,353789..353794,
                     353855..353872,354137..354139,354173..354175,
                     354182..354184,354206..354217,354422..354424)
                     /gene="prpE"
                     /locus_tag="b0335"
                     /gene_synonym="ECK0332; JW0326; yahU"
                     /note="putative active site [active]"
                     /db_xref="CDD:213314"
     misc_feature    order(353546..353548,353708..353713,353720..353722,
                     353789..353791,354206..354214,354404..354406,
                     354422..354424)
                     /gene="prpE"
                     /locus_tag="b0335"
                     /gene_synonym="ECK0332; JW0326; yahU"
                     /note="putative CoA binding site [chemical binding]; other
                     site"
                     /db_xref="CDD:213314"
     repeat_region   354599..354769
                     /note="REP26 (repetitive extragenic palindromic) element;
                     contains 4 REP sequences"
     gene            354922..356181
                     /gene="codB"
                     /locus_tag="b0336"
                     /gene_synonym="ECK0333; JW0327"
                     /db_xref="EcoGene:EG11327"
                     /db_xref="GeneID:944994"
     CDS             354922..356181
                     /gene="codB"
                     /locus_tag="b0336"
                     /gene_synonym="ECK0333; JW0327"
                     /function="transport; Transport of small molecules:
                     Nucleosides, purines, pyrimidines"
                     /GO_component="GO:0009274 - peptidoglycan-based cell wall"
                     /GO_component="GO:0019866 - organelle inner membrane"
                     /GO_process="GO:0015949 - nucleobase, nucleoside and
                     nucleotide interconversion"
                     /note="cytosine permease/transport"
                     /codon_start=1
                     /transl_table=11
                     /product="cytosine transporter"
                     /protein_id="NP_414870.1"
                     /db_xref="GI:16128321"
                     /db_xref="ASAP:ABE-0001159"
                     /db_xref="UniProtKB/Swiss-Prot:P0AA82"
                     /db_xref="EcoGene:EG11327"
                     /db_xref="GeneID:944994"
                     /translation="MSQDNNFSQGPVPQSARKGVLALTFVMLGLTFFSASMWTGGTLG
                     TGLSYHDFFLAVLIGNLLLGIYTSFLGYIGAKTGLTTHLLARFSFGVKGSWLPSLLLG
                     GTQVGWFGVGVAMFAIPVGKATGLDINLLIAVSGLLMTVTVFFGISALTVLSVIAVPA
                     IACLGGYSVWLAVNGMGGLDALKAVVPAQPLDFNVALALVVGSFISAGTLTADFVRFG
                     RNAKLAVLVAMVAFFLGNSLMFIFGAAGAAALGMADISDVMIAQGLLLPAIVVLGLNI
                     WTTNDNALYASGLGFANITGMSSKTLSVINGIIGTVCALWLYNNFVGWLTFLSAAIPP
                     VGGVIIADYLMNRRRYEHFATTRMMSVNWVAILAVALGIAAGHWLPGIVPVNAVLGGA
                     LSYLILNPILNRKTTAAMTHVEANSVE"
     misc_feature    354928..356133
                     /gene="codB"
                     /locus_tag="b0336"
                     /gene_synonym="ECK0333; JW0327"
                     /note="nucleobase-cation-symport-1 (NCS1) transporter
                     CobB-like; solute-binding domain; Region:
                     SLC-NCS1sbd_CobB-like; cd11484"
                     /db_xref="CDD:212053"
     misc_feature    order(355006..355008,355015..355017,355744..355746,
                     355753..355758)
                     /gene="codB"
                     /locus_tag="b0336"
                     /gene_synonym="ECK0333; JW0327"
                     /note="Na binding site [ion binding]; other site"
                     /db_xref="CDD:212053"
     misc_feature    order(355018..355020,355243..355245,355255..355257,
                     355528..355533,355537..355539,355759..355761,
                     355771..355773)
                     /gene="codB"
                     /locus_tag="b0336"
                     /gene_synonym="ECK0333; JW0327"
                     /note="putative substrate binding site [chemical binding];
                     other site"
                     /db_xref="CDD:212053"
     gene            356171..357454
                     /gene="codA"
                     /locus_tag="b0337"
                     /gene_synonym="ECK0334; JW0328"
                     /db_xref="EcoGene:EG11326"
                     /db_xref="GeneID:944996"
     CDS             356171..357454
                     /gene="codA"
                     /locus_tag="b0337"
                     /gene_synonym="ECK0334; JW0328"
                     /EC_number="3.5.4.1"
                     /function="enzyme; Salvage of nucleosides and nucleotides"
                     /GO_component="GO:0005737 - cytoplasm"
                     /GO_process="GO:0015949 - nucleobase, nucleoside and
                     nucleotide interconversion"
                     /codon_start=1
                     /transl_table=11
                     /product="cytosine/isoguanine deaminase"
                     /protein_id="NP_414871.1"
                     /db_xref="GI:16128322"
                     /db_xref="ASAP:ABE-0001161"
                     /db_xref="UniProtKB/Swiss-Prot:P25524"
                     /db_xref="EcoGene:EG11326"
                     /db_xref="GeneID:944996"
                     /translation="MSNNALQTIINARLPGEEGLWQIHLQDGKISAIDAQSGVMPITE
                     NSLDAEQGLVIPPFVEPHIHLDTTQTAGQPNWNQSGTLFEGIERWAERKALLTHDDVK
                     QRAWQTLKWQIANGIQHVRTHVDVSDATLTALKAMLEVKQEVAPWIDLQIVAFPQEGI
                     LSYPNGEALLEEALRLGADVVGAIPHFEFTREYGVESLHKTFALAQKYDRLIDVHCDE
                     IDDEQSRFVETVAALAHHEGMGARVTASHTTAMHSYNGAYTSRLFRLLKMSGINFVAN
                     PLVNIHLQGRFDTYPKRRGITRVKEMLESGINVCFGHDDVFDPWYPLGTANMLQVLHM
                     GLHVCQLMGYGQINDGLNLITHHSARTLNLQDYGIAAGNSANLIILPAENGFDALRRQ
                     VPVRYSVRGGKVIASTQPAQTTVYLEQPEAIDYKR"
     misc_feature    356189..357424
                     /gene="codA"
                     /locus_tag="b0337"
                     /gene_synonym="ECK0334; JW0328"
                     /note="Cytosine deaminase and related metal-dependent
                     hydrolases [Nucleotide transport and metabolism / General
                     function prediction only]; Region: SsnA; COG0402"
                     /db_xref="CDD:223479"
     misc_feature    356192..357385
                     /gene="codA"
                     /locus_tag="b0337"
                     /gene_synonym="ECK0334; JW0328"
                     /note="Bacterial cytosine deaminase and related
                     metal-dependent hydrolases. Cytosine deaminases (CDs)
                     catalyze the deamination of cytosine, producing uracil and
                     ammonia. They play an important role in pyrimidine
                     salvage. CDs are present in prokaryotes and fungi; Region:
                     Bact_CD; cd01293"
                     /db_xref="CDD:238618"
     misc_feature    order(356354..356356,356360..356362,356813..356815,
                     356822..356824,356909..356911,357110..357112)
                     /gene="codA"
                     /locus_tag="b0337"
                     /gene_synonym="ECK0334; JW0328"
                     /note="active site"
                     /db_xref="CDD:238618"
     repeat_region   357484..357562
                     /note="REP27 (repetitive extragenic palindromic) element;
                     contains 2 REP sequences"
     repeat_region   357684..357762
                     /note="REP28 (repetitive extragenic palindromic) element;
                     contains 2 REP sequences"
     gene            complement(357791..358690)
                     /gene="cynR"
                     /locus_tag="b0338"
                     /gene_synonym="ECK0335; JW5894"
                     /db_xref="EcoGene:EG11421"
                     /db_xref="GeneID:945001"
     CDS             complement(357791..358690)
                     /gene="cynR"
                     /locus_tag="b0338"
                     /gene_synonym="ECK0335; JW5894"
                     /function="regulator; Central intermediary metabolism:
                     Pool, multipurpose conversions"
                     /GO_component="GO:0005737 - cytoplasm"
                     /GO_function="GO:0016563 - transcription activator
                     activity"
                     /GO_function="GO:0016564 - transcription repressor
                     activity"
                     /GO_process="GO:0006350 - transcription"
                     /GO_process="GO:0006805 - xenobiotic metabolic process"
                     /note="cyn operon positive regulator"
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional activator of cyn operon;
                     autorepressor"
                     /protein_id="NP_414872.3"
                     /db_xref="GI:157783149"
                     /db_xref="ASAP:ABE-0001165"
                     /db_xref="UniProtKB/Swiss-Prot:P27111"
                     /db_xref="EcoGene:EG11421"
                     /db_xref="GeneID:945001"
                     /translation="MLSRHINYFLAVAEHGSFTRAASALHVSQPALSQQIRQLEESLG
                     VPLFDRSGRTIRLTDAGEVWRQYASRALQELGAGKRAIHDVADLTRGSLRIAVTPTFT
                     SYFIGPLMADFYARYPSITLQLQEMSQEKIEDMLCRDELDVGIAFAPVHSPELEAIPL
                     LTESLALVVAQHHPLAVHEQVALSRLHDEKLVLLSAEFATREQIDHYCEKAGLHPQVV
                     IEANSISAVLELIRRTSLSTLLPAAIATQHDGLKAISLAPPLLERTAVLLRRKNSWQT
                     AAAKAFLHMALDKCAVVGGNESR"
     misc_feature    complement(357809..358690)
                     /gene="cynR"
                     /locus_tag="b0338"
                     /gene_synonym="ECK0335; JW5894"
                     /note="DNA-binding transcriptional regulator CynR;
                     Provisional; Region: PRK11242"
                     /db_xref="CDD:183051"
     misc_feature    complement(358505..358681)
                     /gene="cynR"
                     /locus_tag="b0338"
                     /gene_synonym="ECK0335; JW5894"
                     /note="Bacterial regulatory helix-turn-helix protein, lysR
                     family; Region: HTH_1; pfam00126"
                     /db_xref="CDD:249610"
     misc_feature    complement(357833..358420)
                     /gene="cynR"
                     /locus_tag="b0338"
                     /gene_synonym="ECK0335; JW5894"
                     /note="The C-terminal substrate-binding domain of the
                     LysR-type transcriptional regulator CynR, contains the
                     type 2 periplasmic binding fold; Region: PBP2_CynR;
                     cd08425"
                     /db_xref="CDD:176116"
     misc_feature    complement(order(357983..357985,357989..357994,
                     358001..358006,358013..358018,358022..358039,
                     358121..358123,358313..358330,358349..358351,
                     358358..358363,358367..358372,358385..358387))
                     /gene="cynR"
                     /locus_tag="b0338"
                     /gene_synonym="ECK0335; JW5894"
                     /note="dimerization interface [polypeptide binding]; other
                     site"
                     /db_xref="CDD:176116"
     gene            358799..359458
                     /gene="cynT"
                     /locus_tag="b0339"
                     /gene_synonym="ECK0336; JW0330"
                     /db_xref="EcoGene:EG10176"
                     /db_xref="GeneID:946548"
     CDS             358799..359458
                     /gene="cynT"
                     /locus_tag="b0339"
                     /gene_synonym="ECK0336; JW0330"
                     /EC_number="4.2.1.1"
                     /function="enzyme; Central intermediary metabolism: Pool,
                     multipurpose conversions"
                     /experiment="N-terminus verified by Edman degradation:
                     PMID 1740425"
                     /GO_component="GO:0005737 - cytoplasm"
                     /GO_process="GO:0009440 - cyanate catabolic process"
                     /GO_process="GO:0006805 - xenobiotic metabolic process"
                     /codon_start=1
                     /transl_table=11
                     /product="carbonic anhydrase"
                     /protein_id="NP_414873.1"
                     /db_xref="GI:16128324"
                     /db_xref="ASAP:ABE-0001171"
                     /db_xref="UniProtKB/Swiss-Prot:P0ABE9"
                     /db_xref="EcoGene:EG10176"
                     /db_xref="GeneID:946548"
                     /translation="MKEIIDGFLKFQREAFPKREALFKQLATQQSPRTLFISCSDSRL
                     VPELVTQREPGDLFVIRNAGNIVPSYGPEPGGVSASVEYAVAALRVSDIVICGHSNCG
                     AMTAIASCQCMDHMPAVSHWLRYADSARVVNEARPHSDLPSKAAAMVRENVIAQLANL
                     QTHPSVRLALEEGRIALHGWVYDIESGSIAAFDGATRQFVPLAANPRVCAIPLRQPTA
                     A"
     misc_feature    358817..359374
                     /gene="cynT"
                     /locus_tag="b0339"
                     /gene_synonym="ECK0336; JW0330"
                     /note="Carbonic anhydrases (CA) are zinc-containing
                     enzymes that catalyze the reversible hydration of carbon
                     dioxide in a two-step mechanism in which the nucleophilic
                     attack of a zinc-bound hydroxide ion on carbon dioxide is
                     followed by the regeneration of an...; Region:
                     beta_CA_cladeB; cd00884"
                     /db_xref="CDD:238449"
     misc_feature    order(358886..358888,358892..358894,358913..358915,
                     358919..358927,358961..358963,358970..358972,
                     359045..359047,359060..359062,359090..359092,
                     359099..359101,359342..359344)
                     /gene="cynT"
                     /locus_tag="b0339"
                     /gene_synonym="ECK0336; JW0330"
                     /note="active site clefts [active]"
                     /db_xref="CDD:238449"
     misc_feature    order(358913..358915,358919..358921,359090..359092,
                     359099..359101)
                     /gene="cynT"
                     /locus_tag="b0339"
                     /gene_synonym="ECK0336; JW0330"
                     /note="zinc binding site [ion binding]; other site"
                     /db_xref="CDD:238449"
     misc_feature    order(358916..358927,358931..358933,358937..358948,
                     358961..358969,358973..358975,358979..358981,
                     359030..359035,359042..359047,359162..359164,
                     359342..359344,359348..359353,359357..359359,
                     359363..359365)
                     /gene="cynT"
                     /locus_tag="b0339"
                     /gene_synonym="ECK0336; JW0330"
                     /note="dimer interface [polypeptide binding]; other site"
                     /db_xref="CDD:238449"
     gene            359489..359959
                     /gene="cynS"
                     /locus_tag="b0340"
                     /gene_synonym="cnt; ECK0337; JW0331"
                     /db_xref="EcoGene:EG10175"
                     /db_xref="GeneID:948998"
     CDS             359489..359959
                     /gene="cynS"
                     /locus_tag="b0340"
                     /gene_synonym="cnt; ECK0337; JW0331"
                     /EC_number="4.2.1.104"
                     /function="enzyme; Central intermediary metabolism: Pool,
                     multipurpose conversions"
                     /experiment="N-terminus verified by Edman degradation:
                     PMID 6336748"
                     /GO_process="GO:0009440 - cyanate catabolic process"
                     /GO_process="GO:0006807 - nitrogen compound metabolic
                     process"
                     /GO_process="GO:0006805 - xenobiotic metabolic process"
                     /note="cyanate aminohydrolase, cyanase"
                     /codon_start=1
                     /transl_table=11
                     /product="cyanate aminohydrolase"
                     /protein_id="NP_414874.1"
                     /db_xref="GI:16128325"
                     /db_xref="ASAP:ABE-0001173"
                     /db_xref="UniProtKB/Swiss-Prot:P00816"
                     /db_xref="EcoGene:EG10175"
                     /db_xref="GeneID:948998"
                     /translation="MIQSQINRNIRLDLADAILLSKAKKDLSFAEIADGTGLAEAFVT
                     AALLGQQALPADAARLVGAKLDLDEDSILLLQMIPLRGCIDDRIPTDPTMYRFYEMLQ
                     VYGTTLKALVHEKFGDGIISAINFKLDVKKVADPEGGERAVITLDGKYLPTKPF"
     misc_feature    359504..359956
                     /gene="cynS"
                     /locus_tag="b0340"
                     /gene_synonym="cnt; ECK0337; JW0331"
                     /note="Cyanate lyase [Inorganic ion transport and
                     metabolism]; Region: CynS; COG1513"
                     /db_xref="CDD:224430"
     misc_feature    359747..359956
                     /gene="cynS"
                     /locus_tag="b0340"
                     /gene_synonym="cnt; ECK0337; JW0331"
                     /note="Cyanase C-terminal domain. Cyanase (Cyanate lyase)
                     is responsible for the hydrolysis of cyanate.  It
                     catalyzes the reaction of cyanate with bicarbonate to
                     produce ammonia and carbon dioxide. This allows organisms
                     that possess the enzyme to overcome the...; Region:
                     Cyanase_C; cd00559"
                     /db_xref="CDD:238313"
     misc_feature    order(359756..359767,359771..359776,359780..359785,
                     359789..359791,359798..359800,359813..359815,
                     359819..359821,359825..359836,359840..359851,
                     359858..359863,359876..359878,359882..359884,
                     359909..359914,359918..359920,359924..359926,
                     359930..359938,359945..359947,359954..359956)
                     /gene="cynS"
                     /locus_tag="b0340"
                     /gene_synonym="cnt; ECK0337; JW0331"
                     /note="oligomer interface [polypeptide binding]; other
                     site"
                     /db_xref="CDD:238313"
     misc_feature    order(359774..359776,359852..359857)
                     /gene="cynS"
                     /locus_tag="b0340"
                     /gene_synonym="cnt; ECK0337; JW0331"
                     /note="active site"
                     /db_xref="CDD:238313"
     gene            359992..361146
                     /gene="cynX"
                     /locus_tag="b0341"
                     /gene_synonym="ECK0338; JW0332"
                     /db_xref="EcoGene:EG10177"
                     /db_xref="GeneID: