GenomeNet

Database: RefSeq
Entry: NC_001136
LinkDB: NC_001136
Original site: NC_001136 
LOCUS       NC_001136            1531933 bp    DNA     linear   PLN 22-AUG-2014
DEFINITION  Saccharomyces cerevisiae S288c chromosome IV, complete sequence.
ACCESSION   NC_001136
VERSION     NC_001136.10  GI:330443520
DBLINK      BioProject: PRJNA128
KEYWORDS    RefSeq; TPA:inferential.
SOURCE      Saccharomyces cerevisiae S288c
  ORGANISM  Saccharomyces cerevisiae S288c
            Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina;
            Saccharomycetes; Saccharomycetales; Saccharomycetaceae;
            Saccharomyces.
REFERENCE   1  (bases 1 to 1531933)
  AUTHORS   Jacq,C., Alt-Morbe,J., Andre,B., Arnold,W., Bahr,A., Ballesta,J.P.,
            Bargues,M., Baron,L., Becker,A., Biteau,N., Blocker,H., Blugeon,C.,
            Boskovic,J., Brandt,P., Bruckner,M., Buitrago,M.J., Coster,F.,
            Delaveau,T., del Rey,F., Dujon,B., Eide,L.G.,
            Garcia-Cantalejo,J.M., Goffeau,A., Gomez-Peris,A., Zaccaria,P. et
            al.
  TITLE     The nucleotide sequence of Saccharomyces cerevisiae chromosome IV
  JOURNAL   Nature 387 (6632 SUPPL), 75-78 (1997)
   PUBMED   9169867
REFERENCE   2  (bases 1 to 1531933)
  AUTHORS   Goffeau,A., Barrell,B.G., Bussey,H., Davis,R.W., Dujon,B.,
            Feldmann,H., Galibert,F., Hoheisel,J.D., Jacq,C., Johnston,M.,
            Louis,E.J., Mewes,H.W., Murakami,Y., Philippsen,P., Tettelin,H. and
            Oliver,S.G.
  TITLE     Life with 6000 genes
  JOURNAL   Science 274 (5287), 546 (1996)
   PUBMED   8849441
REFERENCE   3  (bases 1 to 1531933)
  CONSRTM   NCBI Genome Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-AUG-2014) National Center for Biotechnology
            Information, NIH, Bethesda, MD 20894, USA
REFERENCE   4  (bases 1 to 1531933)
  CONSRTM   Saccharomyces Genome Database
  TITLE     Direct Submission
  JOURNAL   Submitted (06-FEB-2013) Department of Genetics, Stanford
            University, Stanford, CA 94305-5120, USA
  REMARK    Protein update by submitter
REFERENCE   5  (bases 1 to 1531933)
  CONSRTM   Saccharomyces Genome Database
  TITLE     Direct Submission
  JOURNAL   Submitted (04-MAY-2012) Department of Genetics, Stanford
            University, Stanford, CA 94305-5120, USA
  REMARK    Protein update by submitter
REFERENCE   6  (bases 1 to 1531933)
  CONSRTM   Saccharomyces Genome Database
  TITLE     Direct Submission
  JOURNAL   Submitted (31-MAR-2011) Department of Genetics, Stanford
            University, Stanford, CA 94305-5120, USA
  REMARK    Sequence update by submitter
REFERENCE   7  (bases 1 to 1531933)
  CONSRTM   Saccharomyces Genome Database
  TITLE     Direct Submission
  JOURNAL   Submitted (11-DEC-2009) Department of Genetics, Stanford
            University, Stanford, CA 94305-5120, USA
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence is identical to BK006938.
            On Apr 26, 2011 this sequence version replaced gi:269970296.
            Sequence assembly version R64-1-1.
            COMPLETENESS: full length.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-5984              Z74296.1           1-5984
            2954-8682           Z74295.1           1-5729
            7815-11656          Z74294.1           1-3842
            9757-16203          Z74293.1           1-6447
            13361-17576         Z74292.1           1-4216
            17227-18958         Z74291.1           1-1732
            18567-20634         Z74290.1           1-2068
            19313-22822         Z74289.1           1-3510
            21007-26402         Z74288.1           1-5396
            25877-28984         Z74287.1           1-3108
            28776-30656         Z74286.1           1-1881
            30455-32295         Z74285.1           1-1841
            31830-33414         Z74284.1           1-1585
            33235-34236         Z74283.1           1-1003
            33919-36796         Z74282.1           1-2879
            35232-38486         Z74281.1           1-3255
            38174-38866         Z74280.1           1-693
            38598-42699         Z74279.1           1-4102
            42245-44064         Z74278.1           1-1820
            43708-46270         Z74277.1           1-2563
            45919-51114         Z74275.1           1-5196
            48032-52444         Z74274.1           1-4413
            52174-54396         Z74273.1           1-2223
            54101-57264         Z74272.1           1-3164
            56347-60871         Z74271.1           1-4525
            60406-62010         Z74270.1           1-1605
            61802-65241         Z74269.1           1-3440
            65019-66492         Z74267.1           1-1474
            65766-67982         Z74266.1           1-2217
            67348-68996         Z74265.1           1-1649
            68607-70639         Z74264.1           1-2033
            70365-74445         Z74263.1           1-4081
            73919-77288         Z74262.1           1-3370
            76546-78425         Z74261.1           1-1880
            77967-79293         Z74260.1           1-1327
            79059-84269         Z74259.1           1-5211
            80413-86206         Z74258.1           1-5794
            85986-87460         Z74257.1           1-1475
            87227-88247         Z74256.1           1-1021
            87983-90175         Z74255.1           1-2193
            89865-92761         Z74254.1           1-2897
            92465-94604         Z74253.1           1-2140
            93746-96081         Z74252.1           1-2336
            95787-98474         Z74251.1           1-2688
            97954-99560         Z74250.1           1-1607
            99225-100500        Z74249.1           1-1276
            100422-101289       Z74248.1           1-868
            100664-103648       Z74247.1           1-2985
            103354-104916       Z74246.1           1-1563
            104552-106740       Z74245.1           1-2189
            106495-107207       Z74244.1           1-713
            107071-111579       Z74243.1           1-4509
            111030-114671       Z74242.1           1-3642
            114235-116320       Z74241.1           1-2086
            115800-117663       Z74240.1           1-1864
            116867-118706       Z74239.1           1-1840
            118518-121977       Z74238.1           1-3460
            121593-123864       Z74237.1           1-2272
            123590-125508       Z74236.1           1-1919
            124999-126786       Z74235.1           1-1788
            126450-130406       Z74233.1           1-3957
            130003-130870       Z74232.1           1-868
            130485-133436       Z74231.1           1-2952
            131834-135178       Z74230.1           1-3345
            133958-135895       Z74229.1           1-1938
            135437-138290       Z74228.1           1-2854
            137540-139521       Z74227.1           1-1982
            139206-141208       Z74226.1           1-2003
            141115-142096       Z74225.1           1-982
            141722-144483       Z74224.1           1-2762
            144224-145825       Z74223.1           1-1602
            145519-148190       Z74222.1           1-2672
            147590-149202       Z74221.1           1-1613
            149087-156317       Z74219.1           1-7231
            155641-158063       Z74218.1           1-2423
            157905-159603       Z74217.1           1-1699
            158736-160994       Z74216.1           1-2259
            160765-163448       Z74215.1           1-2684
            163155-164289       Z74214.1           1-1135
            164043-164986       Z74213.1           1-944
            164866-167358       Z74212.1           1-2493
            167259-170409       Z74210.1           1-3151
            169079-172480       Z74208.1           1-3402
            171931-174231       Z74207.1           1-2301
            174175-174917       Z74205.1           1-743
            174589-176772       Z74204.1           1-2184
            176487-178333       Z74203.1           1-1847
            178057-181185       Z74202.1           1-3129
            181040-183317       Z74201.1           1-2278
            183188-184924       Z74199.1           1-1737
            184612-188153       Z74197.1           1-3542
            187919-190923       Z74196.1           1-3005
            190587-192749       Z74195.1           1-2163
            192262-194570       Z74194.1           1-2309
            194226-198661       Z74193.1           1-4436
            194953-199995       Z74192.1           1-5043
            199742-201718       Z74191.1           1-1977
            201583-203038       Z74190.1           1-1456
            202571-205359       Z74189.1           1-2789
            205112-211374       Z74188.1           1-6263
            210562-213350       Z74187.1           1-2789
            212119-216528       Z74186.1           1-4409
            215643-217599       Z74185.1           1-1956
            217075-218679       Z74184.1           1-1605
            218368-219661       Z74183.1           1-1294
            219289-222426       Z74182.1           1-3138
            220772-224303       Z74181.1           1-3532
            222523-227392       Z74180.1           1-4870
            226752-229905       Z74179.1           1-3154
            228716-231023       Z74178.1           1-2308
            230528-232651       Z74177.1           1-2124
            231900-234926       Z74176.1           1-3027
            233888-236156       Z74175.1           1-2268
            235768-239018       Z74174.1           1-3251
            238665-240258       Z74173.1           1-1594
            239607-241417       Z74172.1           1-1811
            241198-242551       Z74171.1           1-1354
            241841-245132       Z74170.1           1-3292
            244982-245922       Z74169.1           1-941
            245583-246688       Z74168.1           1-1106
            246448-248580       Z74167.1           1-2133
            247683-251565       Z74165.1           1-3883
            251239-253994       Z74164.1           1-2756
            253747-255603       Z74163.1           1-1857
            254718-256632       Z74162.1           1-1915
            256531-258914       Z74161.1           1-2384
            258556-263312       Z74160.1           1-4757
            261776-264511       Z74159.1           1-2736
            264111-265257       Z74158.1           1-1147
            264965-267697       Z74157.1           1-2733
            267202-268920       Z74156.1           1-1719
            268700-270221       Z74155.1           1-1522
            269977-272388       Z74154.1           1-2412
            271902-273652       Z74153.1           1-1751
            273598-275147       Z74152.1           1-1550
            274877-276871       Z74151.1           1-1995
            276582-280306       Z74150.1           1-3725
            280166-282111       Z74149.1           1-1946
            281849-283418       Z74148.1           1-1570
            283177-284580       Z74147.1           1-1404
            284445-285390       Z74146.1           1-946
            285166-286997       Z74145.1           1-1832
            286696-289571       Z74144.1           1-2876
            289513-292780       Z74142.1           1-3268
            292141-293391       Z74140.1           1-1251
            292901-295033       Z74139.1           1-2133
            294760-296819       Z74138.1           1-2060
            296330-298416       Z74137.1           1-2087
            298275-300213       Z74136.1           1-1939
            300004-301412       Z74135.1           1-1409
            301000-303210       Z74134.1           1-2211
            302235-305236       Z74133.1           1-3002
            304849-306925       Z74132.1           1-2077
            306578-308423       Z74131.1           1-1846
            307790-309801       Z74130.1           1-2012
            309389-310641       Z74129.1           1-1253
            310123-312950       Z74128.1           1-2828
            312472-315356       Z74127.1           1-2885
            314749-316970       Z74126.1           1-2222
            316389-320667       Z74125.1           1-4279
            320121-322225       Z74124.1           1-2105
            321553-324046       Z74123.1           1-2494
            322989-326612       Z74122.1           1-3624
            326150-329835       Z74121.1           1-3686
            329568-330665       Z74120.1           1-1099
            330047-333120       Z74119.1           1-3074
            332941-334216       Z74117.1           1-1275
            333830-334834       Z74115.1           1-1005
            334397-336248       Z74114.1           1-1852
            336122-337486       Z74113.1           1-1365
            337302-338271       Z74112.1           1-970
            338071-340627       Z74111.1           1-2557
            340002-341618       Z74109.1           1-1617
            340799-344236       Z74108.1           1-3438
            343986-345664       Z74107.1           1-1679
            344954-351433       Z74106.1           1-6480
            347229-352876       Z74105.1           1-5648
            352421-355673       Z74104.1           1-3253
            355379-359824       Z74103.1           1-4446
            356760-361698       Z74102.1           1-4939
            361286-362671       Z74101.1           1-1386
            362257-363951       Z74100.1           1-1695
            363584-365067       Z74099.1           1-1484
            364818-366738       Z74097.1           1-1921
            365875-369770       Z74096.1           1-3894
            367701-371239       Z74095.1           1-3536
            370707-372687       Z74094.1           1-1980
            371762-373966       Z74093.1           1-2205
            373609-375679       Z74092.1           1-2071
            375290-376756       Z74091.1           1-1467
            376481-378873       Z74090.1           1-2393
            378456-381984       Z74088.1           1-3530
            381439-384600       Z74087.1           1-3162
            384082-387512       Z74085.1           1-3431
            385588-389171       Z74084.1           1-3584
            388902-392658       Z74083.1           1-3757
            392128-394216       Z74081.1           1-2089
            394002-397536       Z74079.1           1-3535
            397205-399339       Z74078.1           1-2135
            399130-400996       Z74077.1           1-1867
            400639-403694       Z74076.1           1-3056
            403292-405343       Z74075.1           1-2052
            405061-408450       Z74073.1           1-3390
            407207-411760       Z74072.1           1-4554
            409858-413952       Z74071.1           1-4095
            413001-415112       Z74069.1           1-2112
            414889-417662       Z74068.1           1-2774
            416709-422832       Z74067.1           1-6124
            420773-424208       Z74066.1           1-3436
            423511-426001       Z74065.1           1-2491
            425873-427363       Z74063.1           1-1491
            426935-429066       Z74062.1           1-2132
            427883-431107       Z74061.1           1-3225
            430927-432307       Z74060.1           1-1381
            431518-433496       Z74059.1           1-1979
            433233-438046       Z74056.1           1-4814
            433995-439908       Z74055.1           1-5914
            439361-441013       Z74054.1           1-1653
            440407-477810       Z48008.1           1-37404
            440755-443028       Z74053.1           1-2274
            443029-470424       "ATGT...GTAA"      1-27396
            470425-473156       Z74308.1           1-2732
            473157-475989       "ATGT...ATAA"      1-2833
            475990-478473       Z74311.1           1-2483
            477677-488627       Z49770.1           1-10951
            478200-479114       Z74312.1           1-915
            478759-482669       Z74313.1           1-3911
            480292-484162       Z74314.1           1-3871
            483861-485745       Z74315.1           1-1885
            485366-486803       Z74316.1           1-1438
            486445-488071       Z74317.1           1-1627
            488004-489507       Z74318.1           1-1504
            488449-503273       Z47814.1           1-14825
            488663-491016       Z74319.1           1-2354
            490897-491514       Z74320.1           1-618
            491145-492555       Z74321.1           1-1411
            492325-494648       Z74322.1           1-2324
            494269-497834       Z74323.1           1-3566
            497835-501414       "CTAA...GTGA"      1-3580
            501415-503497       Z74326.1           1-2083
            503267-527893       Z68196.1           1-24628
            503274-504098       Z74327.1           1-824
            504099-512109       "TCAA...ACAT"      1-8011
            512110-523210       Z74331.1           1-11101
            523211-527215       "TTAT...TTAA"      1-4005
            527216-531306       Z74334.1           1-4091
            527894-535191       Z74335.1           1-7298
            531779-541777       Z54075.1           1-9999
            541755-547918       Z49812.1           1-6165
            547831-588929       Z49209.1           1-41099
            565641-567722       Z74353.1           1-2082
            567723-578159       "TTAA...TTGA"      1-10437
            578160-579457       Z74359.1           1-1299
            579113-580686       Z74360.1           1-1574
            580687-583465       "ATGG...TCAT"      1-2779
            583466-584938       Z74364.1           1-1473
            584132-622891       Z46796.1           1-38760
            589403-592438       Z74368.1           1-3035
            589772-593892       Z74369.1           1-4120
            593893-603399       "ATGA...ATGA"      1-9507
            603400-607303       Z74376.1           1-3904
            607304-609162       "CTAA...TTTT"      1-1859
            609163-612015       Z74378.1           1-2853
            612016-617170       "ATGC...CCAT"      1-5155
            617171-618496       Z74383.1           1-1326
            618307-622111       Z74384.1           1-3805
            619132-625065       Z74385.1           1-5934
            622854-631313       Z50111.1           1-8460
            631241-667457       Z47746.1           1-36217
            665212-704024       Z48758.1           1-38813
            703670-741221       Z48179.1           1-37552
            741200-745540       Z54139.1           1-4341
            745514-788981       Z50046.1           1-43468
            787984-801614       Z47813.1           1-13631
            800596-839930       Z46727.1           1-39334
            838927-858162       Z48784.1           1-19236
            858126-897953       Z68194.1           1-39827
            897516-932101       Z48612.1           1-34586
            932083-962589       Z49701.1           1-30507
            962590-986590       Z68329.1           1-24000
            962590-981170       Z70202.1           1-18581
            979210-994241       Z74387.1           1-15032
            992643-996304       Z70202.1           18592-22253
            992754-996304       Z68290.1           1-3551
            995078-1030143      U51030.1           1-35066
            1027544-1052485     U51031.1           1-24942
            1051686-1095571     U28374.1           1-43887
            1095372-1134546     U32517.2           1-39173
            1133147-1172460     U51032.1           1-39313
            1172061-1203242     U28372.1           1-31184
            1202643-1244775     U28373.1           1-42133
            1237261-1292619     U32274.1           1-55359
            1291770-1370269     U33007.1           1-78500
            1369270-1438278     U33050.4           1-69009
            1437729-1509848     U33057.1           1-72119
            1509733-1527005     U43834.1           1-17267
            1526028-1531933     Z74389.1           1-5906
FEATURES             Location/Qualifiers
     source          1..1531933
                     /organism="Saccharomyces cerevisiae S288c"
                     /mol_type="genomic DNA"
                     /strain="S288c"
                     /db_xref="taxon:559292"
                     /chromosome="IV"
     telomere        complement(1..904)
                     /note="TEL04L; Telomeric region on the left arm of
                     Chromosome IV; composed of an X element core sequence, X
                     element combinatorial repeats, and a terminal stretch of
                     telomeric repeats"
                     /db_xref="SGD:S000028875"
     repeat_region   complement(1..154)
                     /note="TEL04L-TR; Terminal telomeric repeats on the left
                     arm of Chromosome IV"
                     /rpt_family="Telomeric Repeat"
                     /db_xref="SGD:S000028876"
     rep_origin      137..1392
                     /note="ARS400;
                     Autonomously Replicating Sequence"
                     /db_xref="SGD:S000121226"
     repeat_region   complement(155..434)
                     /note="TEL04L-XR; Telomeric X element combinatorial repeat
                     on the left arm of Chr IV; spans 279 bp and contains
                     repeats of the D, C, B and A types, as well as Tbf1p
                     binding sites; formerly called SubTelomeric Repeats"
                     /rpt_family="X element Combinatorial Repeats"
                     /db_xref="SGD:S000028878"
     repeat_region   complement(435..904)
                     /note="TEL04L-XC; Telomeric X element Core sequence on the
                     left arm of Chromosome IV; spans 469 bp and contains an
                     ARS consensus sequence and an Abf1p binding site consensus
                     sequence"
                     /rpt_family="X element Core sequence"
                     /db_xref="SGD:S000028877"
     gene            <1802..>2953
                     /gene="COS7"
                     /locus_tag="YDL248W"
                     /db_xref="GeneID:851348"
     mRNA            <1802..>2953
                     /gene="COS7"
                     /locus_tag="YDL248W"
                     /product="Cos7p"
                     /transcript_id="NM_001180308.1"
                     /db_xref="GI:296143127"
                     /db_xref="GeneID:851348"
     CDS             1802..2953
                     /gene="COS7"
                     /locus_tag="YDL248W"
                     /note="hypothetical protein; member of the DUP380
                     subfamily of conserved, often subtelomerically-encoded
                     proteins; the authentic, non-tagged protein is detected in
                     highly purified mitochondria in high-throughput studies"
                     /codon_start=1
                     /product="Cos7p"
                     /protein_id="NP_010033.1"
                     /db_xref="GI:6319953"
                     /db_xref="SGD:S000002407"
                     /db_xref="GeneID:851348"
                     /translation="MKENEVKDEKSVDVLSFKQLESQKIVLPQDLFRSSFTWFCYEIY
                     KSLAFRIWMLLWLPLSVWWKLSNNCIYPLIVSLLVLFLGPIFVLVICGLSRKRSLSKQ
                     LIQFCKEITENTPSSDPHDWEVVVANLNSYLYENKAWNTKNFFFNATDCEKMFRTTVL
                     EPFSLKKDKAAKVKSFKDSVPYIEEALQVYATGFDKQWKLFITEKSWSPVGLEDVQLP
                     KDIHRSKLTWFLKRIFTIYSLPLWLAFLNCICVSQHFCLAFRILCPGLFFLMMVWLFQ
                     NMRTTALLVKMEHKMQFLLTIINEQESGANGWDEIARKMNRYLFEKKAWKNEEFFFDG
                     IDCEWFFSHFFYRLLSAKKSMWLLPLNVELWPYIKEAQLSRNEESLMKK"
     gene            <5985..>7814
                     /gene="MPH2"
                     /locus_tag="YDL247W"
                     /db_xref="GeneID:851350"
     mRNA            <5985..>7814
                     /gene="MPH2"
                     /locus_tag="YDL247W"
                     /product="Mph2p"
                     /transcript_id="NM_001180307.1"
                     /db_xref="GI:296143128"
                     /db_xref="GeneID:851350"
     CDS             5985..7814
                     /gene="MPH2"
                     /locus_tag="YDL247W"
                     /note="Alpha-glucoside permease; transports maltose,
                     maltotriose, alpha-methylglucoside, and turanose;
                     identical to Mph3p; encoded in a subtelomeric position in
                     a region likely to have undergone duplication"
                     /codon_start=1
                     /product="Mph2p"
                     /protein_id="NP_010034.1"
                     /db_xref="GI:6319954"
                     /db_xref="SGD:S000002406"
                     /db_xref="GeneID:851350"
                     /translation="MKNLSFLINRRKENTSDSNVYPGKAKSHEPSWIEMDDQTKKDGL
                     DIVHVEFSPDTRAPSDSNKVITEIFDATEDAKEADESERGMPLATALNTYPKAAAWSL
                     LVSTTLIMEGYDTAILGAFYALPIFQRKFGSQNDKTGEWEISASWQIGLTLCYMAGEI
                     VGLQLTGPSVDLVGNRYTLIIALFFLAAFTFILYFCNSLGMIAVGQALCGMPWGCFQC
                     LTVSYASEICPLALRYYLTTYSNLCWLFGQLFAAGIMKNSQKKYADSELGYKLPFALQ
                     WILPVPLALGIFFAPESPWWLVKKGRFDEARRSLRRTLSGKGPEKEILVTLEVDKIKV
                     TIDKEKRLTSKEGSYSDCFEDKINRRRTRITCLCWAGQATCGSILIGYSTYFYEKAGV
                     STEMSFTFSIIQYCLGICATFLSWWASKYFGRYDLYAFGLAFQTIVFFIIGGLGCSST
                     HGSKMGSGSLLMAVAFFYNLGIAPVVFCLVSEMPSSRLRTKTIILARNTYNVVSIICS
                     VLILYQLNSKKWNWGAKSGFFWGVLCFCTLIWAVVDLPETAGKTFVEINELFKLGVSA
                     RKFKSTKVDPFVVKTPLKTSLITTPREISKLPLQRNSNVSHHL"
     gene            complement(<8683..>9756)
                     /gene="SOR2"
                     /locus_tag="YDL246C"
                     /db_xref="GeneID:851351"
     mRNA            complement(<8683..>9756)
                     /gene="SOR2"
                     /locus_tag="YDL246C"
                     /product="L-iditol 2-dehydrogenase SOR2"
                     /transcript_id="NM_001180306.1"
                     /db_xref="GI:296143129"
                     /db_xref="GeneID:851351"
     CDS             complement(8683..9756)
                     /gene="SOR2"
                     /locus_tag="YDL246C"
                     /EC_number="1.1.1.14"
                     /note="hypothetical protein; protein sequence is 99%
                     identical to the Sor1p sorbitol dehydrogenase;
                     computational analysis of large-scale protein-protein
                     interaction data also suggests a role in fructose or
                     mannose metabolism"
                     /codon_start=1
                     /product="L-iditol 2-dehydrogenase SOR2"
                     /protein_id="NP_010035.1"
                     /db_xref="GI:6319955"
                     /db_xref="SGD:S000002405"
                     /db_xref="GeneID:851351"
                     /translation="MSQNSNPAVVLEKVGDIAIEQRPIPTIKDPHYVKLAIKATGICG
                     SDIHYYRSGGIGKYILKAPMVLGHESSGQVVEVGDAVTRVKVGDRVAIEPGVPSRYSD
                     ETKEGSYNLCPHMAFAATPPIDGTLVKYYLSPEDFLVKLPEGVSYEEGACVEPLSVGV
                     HSNKLAGVRFGTKVVVFGAGPVGLLTGAVARAFGATDVIFVDVFDNKLQRAKDFGATN
                     TFNSSQFSTDKAQDLADGVQKLLGGNHADVVFECSGADVCIDAAVKTTKVGGTMVQVG
                     MGKNYTNFPIAEVSGKEMKLIGCFRYSFGDYRDAVNLVATGKVNVKPLITHKFKFEDA
                     AKAYDYNIAHGGEVVKTIIFGPE"
     gene            complement(<11657..>13360)
                     /gene="HXT15"
                     /locus_tag="YDL245C"
                     /db_xref="GeneID:851352"
     mRNA            complement(<11657..>13360)
                     /gene="HXT15"
                     /locus_tag="YDL245C"
                     /product="Hxt15p"
                     /transcript_id="NM_001180305.1"
                     /db_xref="GI:296143130"
                     /db_xref="GeneID:851352"
     CDS             complement(11657..13360)
                     /gene="HXT15"
                     /locus_tag="YDL245C"
                     /note="hypothetical protein with similarity to hexose
                     transporters; expression is induced by low levels of
                     glucose and repressed by high levels of glucose"
                     /codon_start=1
                     /product="Hxt15p"
                     /protein_id="NP_010036.1"
                     /db_xref="GI:6319956"
                     /db_xref="SGD:S000002404"
                     /db_xref="GeneID:851352"
                     /translation="MASEQSSPEINADNLNSSAADVHVQPPGEKEWSDGFYDKEVING
                     NTPDAPKRGFLGYLIIYLLCYPVSFGGFLPGWDSGITAGFINMDNFKMNFGSYKHSTG
                     EYYLSNVRMGLLVAMFSVGCSIGGVAFARLADTLGRRLAIVIVVLVYMVGAIIQISSN
                     HKWYQYFVGKIIYGLGAGGCSVLCPMLLSEIAPTDLRGGLVSLYQLNMTFGIFLGYCS
                     VYGTRKYSNTAQWRIPVGLCFLWALIIIVGMLLVPESPRYLIECERHEEACVSIAKIN
                     KVSPEDPWVLKQADEINAGVLAQRELGEASWKELFSVKTKVLQRLITGILVQTFLQLT
                     GENYFFFYGTTIFKSVGLTDGFETSIVLGTVNFFSTIIAVMVVDKIGRRKCLLFGAAS
                     MMACMVIFASIGVKCLYPHGQDGPSSKGAGNAMIVFTCFYIFCFATTWAPVAYIVVAE
                     SFPSKVKSKAMSISTAFNWLWQFLIGFFTPFITGSIHFYYGYVFVGCLVAMFLYVFFF
                     LPETIGLSLEEIQLLYEEGIKPWKSASWVPPSRRGASSRETEAKKKSWKEVLKFPKSF
                     N"
     rep_origin      15493..15739
                     /note="ARS403;
                     Autonomously Replicating Sequence"
                     /db_xref="SGD:S000118427"
     gene            <16204..>17226
                     /gene="THI13"
                     /locus_tag="YDL244W"
                     /db_xref="GeneID:851353"
     mRNA            <16204..>17226
                     /gene="THI13"
                     /locus_tag="YDL244W"
                     /product="Thi13p"
                     /transcript_id="NM_001180304.1"
                     /db_xref="GI:296143131"
                     /db_xref="GeneID:851353"
     CDS             16204..17226
                     /gene="THI13"
                     /locus_tag="YDL244W"
                     /note="Protein involved in synthesis of the thiamine
                     precursor HMP; member of a subtelomeric gene family
                     including THI5, THI11, THI12, and THI13;
                     hydroxymethylpyrimidine is also known as HMP"
                     /codon_start=1
                     /product="Thi13p"
                     /protein_id="NP_010037.1"
                     /db_xref="GI:6319957"
                     /db_xref="SGD:S000002403"
                     /db_xref="GeneID:851353"
                     /translation="MSTDKITFLLNWQPTPYHIPIFLAQTKGYFKEQGLDIAILEPTN
                     PSDVTELIGSGKVDMGLKAMIHTLAAKARGFPVTSVASLLDEPFTGVLYLKGSGITED
                     FQSLKGKKIGYVGEFGKIQIDELTKHYGMKPEDYTAVRCGMNVAKYIIEGKIDAGIGI
                     ECMQQVELEEYLAKQGRPASDAKMLRIDKLACLGCCCFCTVLYICNDEFLKKNPEKVR
                     KFLKAIKKATDYVLADPVKAWKEYIDFKPQLNNDLSYKQYQRCYAYFSSSLYNVHRDW
                     KKVTGYGKRLAILPPDYVSNYTNEYLSWPEPEEVSDPLEAQRLMAIHQEKCRQEGTFK
                     RLALPA"
     gene            complement(<17577..>18566)
                     /gene="AAD4"
                     /locus_tag="YDL243C"
                     /db_xref="GeneID:851354"
     mRNA            complement(<17577..>18566)
                     /gene="AAD4"
                     /locus_tag="YDL243C"
                     /product="Aad4p"
                     /transcript_id="NM_001180303.1"
                     /db_xref="GI:296143132"
                     /db_xref="GeneID:851354"
     CDS             complement(17577..18566)
                     /gene="AAD4"
                     /locus_tag="YDL243C"
                     /EC_number="1.1.1.-"
                     /note="Putative aryl-alcohol dehydrogenase; involved in
                     oxidative stress response; similar to P. chrysosporium
                     aryl-alcohol dehydrogenase; expression induced in cells
                     treated with the mycotoxin patulin; members of the AAD
                     gene family comprise three pairs (AAD3 + AAD15, AAD6/AAD16
                     + AAD4, AAD10 + AAD14) whose two genes are more related to
                     one another than to other members of the family"
                     /codon_start=1
                     /product="Aad4p"
                     /protein_id="NP_010038.1"
                     /db_xref="GI:6319958"
                     /db_xref="SGD:S000002402"
                     /db_xref="GeneID:851354"
                     /translation="MGSMNKEQAFELLDAFYEAGGNCIDTANSYQNEESEIWIGEWMK
                     SRKLRDQIVIATKFTGDYKKYEVGGGKSANYCGNHKHSLHVSVRDSLRKLQTDWIDIL
                     YVHWWDYMSSIEEVMDSLHILVQQGKVLYLGVSDTPAWVVSAANYYATSHGKTPFSIY
                     QGKWNVLNRDFERDIIPMARHFGMALAPWDVMGGGRFQSKKAMEERKKNGEGLRTVSG
                     TSKQTDKEVKISEALAKVAEEHGTESVTAIAIAYVRSKAKNVFPLVGGRKIEHLKQNI
                     EALSIKLTPEQIEYLESIIPFDVGFPTNFIGDDPAVTKKASLLTAMSAQISFD"
     gene            <20635..>21006
                     /locus_tag="YDL241W"
                     /db_xref="GeneID:851356"
     mRNA            <20635..>21006
                     /locus_tag="YDL241W"
                     /product="hypothetical protein"
                     /transcript_id="NM_001180301.1"
                     /db_xref="GI:296143133"
                     /db_xref="GeneID:851356"
     CDS             20635..21006
                     /locus_tag="YDL241W"
                     /note="hypothetical protein; YDL241W is not an essential
                     gene"
                     /codon_start=1
                     /product="hypothetical protein"
                     /protein_id="NP_010040.1"
                     /db_xref="GI:6319960"
                     /db_xref="SGD:S000002400"
                     /db_xref="GeneID:851356"
                     /translation="MNVTENALLFKCGSKGYINQTYTPTEIYNCGVAEGKKTAKEKNP
                     TYSIFYDTFLTGQPAESPETFTCGSHGFTNASYVASDFYACGFLQGKGTETNAGIHNT
                     RPSHSLAKFTILFMLVLYTIV"
     gene            <22823..>25876
                     /gene="LRG1"
                     /locus_tag="YDL240W"
                     /db_xref="GeneID:851358"
     mRNA            <22823..>25876
                     /gene="LRG1"
                     /locus_tag="YDL240W"
                     /product="Lrg1p"
                     /transcript_id="NM_001180300.2"
                     /db_xref="GI:330443490"
                     /db_xref="GeneID:851358"
     CDS             22823..25876
                     /gene="LRG1"
                     /locus_tag="YDL240W"
                     /note="GTPase-activating protein (GAP); contains
                     Rho1p-specific GAP activity, interacting with activated
                     forms of Rho1p; functions along with Sac7p as a negative
                     regulator of the Pkc1p-mediated cell wall integrity
                     signaling pathway; negative regulator of cell wall
                     1,3-beta-glucan biosynthesis; required for efficient cell
                     fusion; contains a RhoGAP domain and three
                     Lin-11-Isl1-Mec-3 (LIM) domains"
                     /codon_start=1
                     /product="Lrg1p"
                     /protein_id="NP_010041.2"
                     /db_xref="GI:330443491"
                     /db_xref="SGD:S000002399"
                     /db_xref="GeneID:851358"
                     /translation="MIQNSAGYRSLNTASPMTVQVKNQKKICARCNKLVIPDSQRTKT
                     TLKALGKYYHESCFTCQDCQKPLKPKYFPYQVDKTSESILLCQYDYFRRHNLLCHVCD
                     TPLRGLYYTAFGYRYDEEHFSCTICATPCGVKKCFMYGNQLYCKYHFLKYFSKRCKGC
                     EFPISDQYIEFPKGEEIHCWHPECYGIHKYWHVNLAAETVGLQYLPKLEYNPNSGDKD
                     INPTAYELDKQMQAFNFILSKTWSVLYRFEEEAASCISDMFQYLTSNDQLKGIESTGL
                     LVLKIDCLFRGLDTLNLSTNKSMPVNSDQECIENNAMAASKYSKFPKNLSTKIMIYLQ
                     LLRKLGTENKNETITISSFMSVITGLAHFLKLLTRFGLYTALENNKLTHSVNPLLRFL
                     REVEKNELFENNPFQYIKTPVNATDSCAGCNKYIQEECIQFYEHRWHIACFTCSSCHK
                     NINPRSLTDPTFNKEKKKILCSHCSIDDPASVPGFKFVTKLAQLIFLLKIALVKSRTV
                     MLKSKASNKVGRNSLQSTMLKEQTYIRTLNDIKRLRSRRESVRVTHNKQQARKSVILE
                     TAETDLNDPTKQGDSKNLVIQTDDPSSSQQVSTRENVFSNTKTLTLDDISRIVAAEQA
                     RELRPNAFAHFKKLKETDDETSNVVPKKSGVYYSELSTMELSMIRAISLSLLAGKQLI
                     SKTDPNYTSLVSMVFSNEKQVTGSFWNRMKIMMSMEPKKPITKTVFGAPLDVLCEKWG
                     VDSDLGVGPVKIRIPIIIDELISSLRQMDMSVEGIFRKNGNIRRLRELTANIDSNPTE
                     APDFSKENAIQLSALLKKFIRELPQPILSTDLYELWIKAAKIDLEDEKQRVILLIYSL
                     LPTYNRNLLEALLSFLHWTSSFSYIENEMGSKMDIHNLSTVITPNILYLRHKEISNDN
                     VPDEPESGLVDSFAQNKGENYFLAIEIVDYLITHNEEMAMVPKFLMNLLKDVQLQKLD
                     NYESINHFISTVMQSKTIDYSECDIKTPVTVKDSTTTVIQGEINK"
     gene            complement(<26403..>28775)
                     /gene="ADY3"
                     /locus_tag="YDL239C"
                     /db_xref="GeneID:851359"
     mRNA            complement(<26403..>28775)
                     /gene="ADY3"
                     /locus_tag="YDL239C"
                     /product="Ady3p"
                     /transcript_id="NM_001180299.2"
                     /db_xref="GI:330443492"
                     /db_xref="GeneID:851359"
     CDS             complement(26403..28775)
                     /gene="ADY3"
                     /locus_tag="YDL239C"
                     /note="Protein required for spore wall formation; thought
                     to mediate assembly of a Don1p-containing structure at the
                     leading edge of the prospore membrane via interaction with
                     spindle pole body components; potentially phosphorylated
                     by Cdc28p; ADY3 has a paralog, CNM67, that arose from the
                     whole genome duplication"
                     /codon_start=1
                     /product="Ady3p"
                     /protein_id="NP_010042.2"
                     /db_xref="GI:330443493"
                     /db_xref="SGD:S000002398"
                     /db_xref="GeneID:851359"
                     /translation="MNHWLAFLNKPESLKEQNSDCDQQGEMRHVTDGTLTKSPESKPF
                     RERRSQTWIDSEVPTSTEKSNVQESISSDIISKLSNRRSRRNRSESWAGSEASSPSGN
                     ISTLENATEKNTLKSPNKFLQRGGLPTVGIGSQALSPAGKPSTLGNVSPGKFTTYKVH
                     NSIEVNRFSSTPTKLLTNPHKVAAISNDEHYVVSNESLEENIEVAHLENVFRSSKTPD
                     EEQSEYMKLGEIRLSSSSYGGSISKENSLPKVLDELQSQNEEIKALRQKLEEKDDRIQ
                     ELEELNSMNDAKLQRIEDLQKEFHNERKAASKRLNIVQDRFRKEIKKIREEKITDFQN
                     KNASKKEKNEVTSAKTKCKAFSQRNILVSELYRKQKQILNLQQENDKFLKDINESNNS
                     IVKLRSEVEILKSNLQLSQDENKKLHDNGSFYEKRLNDVYSYMQNLSLFEKDLGKFIL
                     EEMKCGHSPSMFQNGFAKLYPDFQDIKNLENMEQYKQLKGKIELLEKNDRIRLEKIIS
                     VFKLINERLHFMQQQHSHKIKYLQKEALTKEQQFRLEKRRWHDILNLKEENFQKLKSE
                     LKEKLILSEKIQKNAEDKLNDYMNEHQEIVEKLQNQALIASRWSTQIQESENTHKKIT
                     DELAGKQSEILKLEETILSLKEDVFQEKLNLKKLYGDPSTELNFETVGKSFPHITKEK
                     YDSLGLDILTDLTYVQSQNLIKNLLIVLDIPLKTFLKIVPTIVIQLRCELTLLTKFAN
                     DLNLKVFGKQLDFKSRRKVAMNEFLNNHDIAEVKHPLEYDLQALFKYFFS"
     gene            complement(<28985..>30454)
                     /gene="GUD1"
                     /locus_tag="YDL238C"
                     /db_xref="GeneID:851360"
     mRNA            complement(<28985..>30454)
                     /gene="GUD1"
                     /locus_tag="YDL238C"
                     /product="guanine deaminase"
                     /transcript_id="NM_001180298.1"
                     /db_xref="GI:296143136"
                     /db_xref="GeneID:851360"
     CDS             complement(28985..30454)
                     /gene="GUD1"
                     /locus_tag="YDL238C"
                     /EC_number="3.5.4.3"
                     /note="Guanine deaminase; a catabolic enzyme of the
                     guanine salvage pathway producing xanthine and ammonia
                     from guanine; activity is low in exponentially-growing
                     cultures but expression is increased in post-diauxic and
                     stationary-phase cultures"
                     /codon_start=1
                     /product="guanine deaminase"
                     /protein_id="NP_010043.1"
                     /db_xref="GI:6319963"
                     /db_xref="SGD:S000002397"
                     /db_xref="GeneID:851360"
                     /translation="MTKSDLLFDKFNDKHGKFLVFFGTFVDTPKLGELRIREKTSVGV
                     LNGIIRFVNRNSLDPVKDCLDHDSSLSPEDVTVVDIIGKDKTRNNSFYFPGFVDTHNH
                     VSQYPNVGVFGNSTLLDWLEKYTFPIEAALANENIAREVYNKVISKTLSHGTTTVAYY
                     NTIDLKSTKLLAQLSSLLGQRVLVGKVCMDTNGPEYYIEDTKTSFESTVKVVKYIRET
                     ICDPLVNPIVTPRFAPSCSRELMQQLSKLVKDENIHVQTHLSENKEEIQWVQDLFPEC
                     ESYTDVYDKYGLLTEKTVLAHCIHLTDAEARVIKQRRCGISHCPISNSSLTSGECRVR
                     WLLDQGIKVGLGTDVSAGHSCSILTTGRQAFAVSRHLAMRETDHAKLSVSECLFLATM
                     GGAQVLRMDETLGTFDVGKQFDAQMIDTNAPGSNVDMFHWQLKEKDQMQEQEQEQGQD
                     PYKNPPLLTNEDIIAKWFFNGDDRNTTKVWVAGQQVYQI"
     gene            <30657..>31829
                     /gene="AIM6"
                     /locus_tag="YDL237W"
                     /db_xref="GeneID:851361"
     mRNA            <30657..>31829
                     /gene="AIM6"
                     /locus_tag="YDL237W"
                     /product="Aim6p"
                     /transcript_id="NM_001180297.2"
                     /db_xref="GI:330443494"
                     /db_xref="GeneID:851361"
     CDS             30657..31829
                     /gene="AIM6"
                     /locus_tag="YDL237W"
                     /note="hypothetical protein; required for respiratory
                     growth; YDL237W is not an essential gene"
                     /codon_start=1
                     /product="Aim6p"
                     /protein_id="NP_010044.2"
                     /db_xref="GI:330443495"
                     /db_xref="SGD:S000002396"
                     /db_xref="GeneID:851361"
                     /translation="MLGLKGCLTILIGYVIAVCALFSSRGRNPSLTDWEKLKDQKISN
                     IDNFGLTGQHLLEFFQENLPFLSFSEEKYRHKHVSLYYDVFKEYILRRASSKKCLPVD
                     SAIAKLNKDVNPMPVHSHNDYWRKLPLFEGLAYGASSTEADVWNIDEKILAVGHNEAY
                     LDPVELTLDKLYTGPLLEILDEVNCQDSDADRKNGVFFNSPETSLFFYIDFKSDDNEL
                     TYKLLMEQYFKSLIDSGYLTYYDMKKDEIIWRPVTVILTGNYPTSLDILDNGNDNGYF
                     ESSQRFAFLDAPLLSLEPKYSKLSVAATVSFSQLMKHCGSDHWKVSLRGRMDSNEISC
                     AKSIIDGAHALKLKTRIWGAPTWPANLVETISRQIIHDLGSDLLNLDNLFMASSLI"
     gene            <32296..>33234
                     /gene="PHO13"
                     /locus_tag="YDL236W"
                     /db_xref="GeneID:851362"
     mRNA            <32296..>33234
                     /gene="PHO13"
                     /locus_tag="YDL236W"
                     /product="Pho13p"
                     /transcript_id="NM_001180296.1"
                     /db_xref="GI:296143138"
                     /db_xref="GeneID:851362"
     CDS             32296..33234
                     /gene="PHO13"
                     /locus_tag="YDL236W"
                     /EC_number="3.1.3.41"
                     /note="Alkaline phosphatase specific for p-nitrophenyl
                     phosphate; also has protein phosphatase activity"
                     /codon_start=1
                     /product="Pho13p"
                     /protein_id="NP_010045.1"
                     /db_xref="GI:6319965"
                     /db_xref="SGD:S000002395"
                     /db_xref="GeneID:851362"
                     /translation="MTAQQGVPIKITNKEIAQEFLDKYDTFLFDCDGVLWLGSQALPY
                     TLEILNLLKQLGKQLIFVTNNSTKSRLAYTKKFASFGIDVKEEQIFTSGYASAVYIRD
                     FLKLQPGKDKVWVFGESGIGEELKLMGYESLGGADSRLDTPFDAAKSPFLVNGLDKDV
                     SCVIAGLDTKVNYHRLAVTLQYLQKDSVHFVGTNVDSTFPQKGYTFPGAGSMIESLAF
                     SSNRRPSYCGKPNQNMLNSIISAFNLDRSKCCMVGDRLNTDMKFGVEGGLGGTLLVLS
                     GIETEERALKISHDYPRPKFYIDKLGDIYTLTNNEL"
     gene            complement(<33415..>33918)
                     /gene="YPD1"
                     /locus_tag="YDL235C"
                     /db_xref="GeneID:851363"
     mRNA            complement(<33415..>33918)
                     /gene="YPD1"
                     /locus_tag="YDL235C"
                     /product="Ypd1p"
                     /transcript_id="NM_001180295.1"
                     /db_xref="GI:296143139"
                     /db_xref="GeneID:851363"
     CDS             complement(33415..33918)
                     /gene="YPD1"
                     /locus_tag="YDL235C"
                     /note="Phosphorelay intermediate protein; phosphorylated
                     by the plasma membrane sensor Sln1p in response to osmotic
                     stress and then in turn phosphorylates the response
                     regulators Ssk1p in the cytosol and Skn7p in the nucleus"
                     /codon_start=1
                     /product="Ypd1p"
                     /protein_id="NP_010046.1"
                     /db_xref="GI:6319966"
                     /db_xref="SGD:S000002394"
                     /db_xref="GeneID:851363"
                     /translation="MSTIPSEIINWTILNEIISMDDDDSDFSKGLIIQFIDQAQTTFA
                     QMQRQLDGEKNLTELDNLGHFLKGSSAALGLQRIAWVCERIQNLGRKMEHFFPNKTEL
                     VNTLSDKSIINGINIDEDDEEIKIQVDDKDENSIYLILIAKALNQSRLEFKLARIELS
                     KYYNTNL"
     gene            complement(<34237..>36477)
                     /gene="GYP7"
                     /locus_tag="YDL234C"
                     /db_xref="GeneID:851364"
     mRNA            complement(<34237..>36477)
                     /gene="GYP7"
                     /locus_tag="YDL234C"
                     /product="Gyp7p"
                     /transcript_id="NM_001180294.1"
                     /db_xref="GI:296143140"
                     /db_xref="GeneID:851364"
     CDS             complement(34237..36477)
                     /gene="GYP7"
                     /locus_tag="YDL234C"
                     /note="GTPase-activating protein for yeast Rab family
                     members; members include Ypt7p (most effective), Ypt1p,
                     Ypt31p, and Ypt32p (in vitro); involved in vesicle
                     mediated protein trafficking"
                     /codon_start=1
                     /product="Gyp7p"
                     /protein_id="NP_010047.1"
                     /db_xref="GI:6319967"
                     /db_xref="SGD:S000002393"
                     /db_xref="GeneID:851364"
                     /translation="MSKILFCKSKVFLHPTSDARDNIAGFLLLTLEANKLSHQAILQY
                     IPESGLSTLEISKLLKHEAKVGTCPTSTPFVIENSINFSNLVNTSLGQAFEISLSQIY
                     CIQFRPPSPNGWYVGSLVIYPLTEQFTGFQPPVLFFHDQLCPSTTDKLKRLRKSMNPF
                     DDSDELYWGGVDLRNKINELMELKKSNLEPEFWLVNPSLNDLRNFVSKDLLESYNNSK
                     KDTTELATAGVKLNEKFQEWKWNVMSKIADVTTKSTNFIDSWLTNNSPIQKSQIDNEY
                     LQKLLNNEKVKQIEQDYDSARVYLANWSLGVKQEAERYQKQNKLFDSYRNNIFNDLNL
                     TDELSDTEINNALQRQFPLTEAKWNSLWDENDGRLRVTVNEVKDFIFHGGLENDSLRG
                     KVWGFLLEIYPWDSSQDERVQIDQTLAAEYDQLKLTWSKDFLQFDDEDEEEYWNDQLF
                     RISKDVRRCDRNLEIFQYNTIDGLPPPPQQLPANENNSTSPESANDESDDADDGVRNP
                     HLIHLQNILITYNVYNTNLGYVQGMTDLLSPIYVIMKEEWKTFWCFTHFMDIMERNFL
                     RDQSGIHEQMLTLVELVQLMLPELSEHLNKCDSGNLFFCFRMLLVWFKREFEMEDIMH
                     IWENFWTFYYSSQFQLFFMLAILQKNSQAILQHLNQFDQILKFFNELNGKLDWNDLMV
                     RAELLFKKFEKMMHVMERDLQNVSSSSSSSSTGVLPCQSERLTLLLSKKPIIRHEGQR
                     SKNSVK"
     gene            <36797..>38173
                     /gene="MFG1"
                     /locus_tag="YDL233W"
                     /db_xref="GeneID:851365"
     mRNA            <36797..>38173
                     /gene="MFG1"
                     /locus_tag="YDL233W"
                     /product="Mfg1p"
                     /transcript_id="NM_001180293.1"
                     /db_xref="GI:296143141"
                     /db_xref="GeneID:851365"
     CDS             36797..38173
                     /gene="MFG1"
                     /locus_tag="YDL233W"
                     /note="Regulator of filamentous growth; interacts with
                     FLO11 promoter and regulates FLO11 expression; binds to
                     transcription factors Flo8p and Mss11p; green fluorescent
                     protein (GFP)-fusion protein localizes to the nucleus;
                     YDL233W is not an essential gene"
                     /codon_start=1
                     /product="Mfg1p"
                     /protein_id="NP_010048.1"
                     /db_xref="GI:6319968"
                     /db_xref="SGD:S000002392"
                     /db_xref="GeneID:851365"
                     /translation="MYQGPPQPPPQAVPMPYIVNNNTPPYPNGNINFPPTAQQNIPPT
                     VYPQQVPFPGQPQGGQFPQPSSEQQVFNQLPQVTQTFHNSAQNTNATGGPGSGSMPMF
                     TPVASFPHPMATAATAAAPLPRSASQASLSMLRVPYHVRKYLSNLAMLKLYEIINEVN
                     TAMGKIGLLSFWTELISDIFTPDAVIRYSKKSMTDYREFEFIIPVFPVICSTLGRFGI
                     VRMEVKVLQLKTQVLSNSTIFFNCPRVTFVYYYPDGSYITHFSQMKGAFDLDLKINWL
                     DVSMHSFVPDIEWNAVERLLSDDTKSTEIEQIFRKLKQEDVKEQGNSFAENNATNVPP
                     NFEAITQLRSYFDVFRNVSVFGTQEGLMRVMQISTVMSTLKNLRKFQIEKNIDSPVTA
                     LSAYIDADKKDSGSEPLHAKRRRNSGISPRTTTLGPNGNSNTSNEELPTSDVNDINKD
                     MTKKKMKF"
     gene            <38487..>38597
                     /gene="OST4"
                     /locus_tag="YDL232W"
                     /db_xref="GeneID:851366"
     mRNA            <38487..>38597
                     /gene="OST4"
                     /locus_tag="YDL232W"
                     /product="Ost4p"
                     /transcript_id="NM_001180292.1"
                     /db_xref="GI:296143142"
                     /db_xref="GeneID:851366"
     CDS             38487..38597
                     /gene="OST4"
                     /locus_tag="YDL232W"
                     /EC_number="2.4.99.18"
                     /note="Subunit of the oligosaccharyltransferase complex of
                     the ER lumen; complex catalyzes protein asparagine-linked
                     glycosylation; type I membrane protein required for
                     incorporation of Ost3p or Ost6p into the OST complex"
                     /codon_start=1
                     /product="Ost4p"
                     /protein_id="NP_010049.1"
                     /db_xref="GI:6319969"
                     /db_xref="SGD:S000002391"
                     /db_xref="GeneID:851366"
                     /translation="MISDEQLNSLAITFGIVMMTLIVIYHAVDSTMSPKN"
     gene            complement(<38867..>42244)
                     /gene="BRE4"
                     /locus_tag="YDL231C"
                     /db_xref="GeneID:851367"
     mRNA            complement(<38867..>42244)
                     /gene="BRE4"
                     /locus_tag="YDL231C"
                     /product="Bre4p"
                     /transcript_id="NM_001180291.1"
                     /db_xref="GI:296143143"
                     /db_xref="GeneID:851367"
     CDS             complement(38867..42244)
                     /gene="BRE4"
                     /locus_tag="YDL231C"
                     /note="Zinc finger protein containing five transmembrane
                     domains; null mutant exhibits strongly fragmented vacuoles
                     and sensitivity to brefeldin A, a drug which is known to
                     affect intracellular transport"
                     /codon_start=1
                     /product="Bre4p"
                     /protein_id="NP_010050.1"
                     /db_xref="GI:6319970"
                     /db_xref="SGD:S000002390"
                     /db_xref="GeneID:851367"
                     /translation="MKRYERDRSPTPDPDIVKGSYSQTSLRSLHELNYKNPAGISGLS
                     FAGSPQQSVASLSQMRLENLVKDKHWEEVEDFGLEELRDGFFDAAFTKPDSKARSPNS
                     DIDDDNGAARKKLQSGFTKLSEYVWTAIYRPIIHFPRDIRKNGVSIFKFFIAYFIAIV
                     ICVIRPSGRWIGHEFRYFLPIAVLIHHPVRNIGVQLEMTISSIIGASFGLGWSALAWY
                     ISTATKPTANYQGGILFQSLTMALLFAIWLRSVYRRFFYFTTSFSISIIFTHTVRLAS
                     SKFDLKWQIFWDFGISYLFGLLLSLLVCVCVSPHSGNAELMEHYNKCLQTTKTFLMAL
                     VDTELIKSKEQIYLAQVKMVKTLNIDLSQGFRDFVNQLTISRFDLQSLKSLRNSLTAM
                     ETSLRVLPIAPKIFNDDELKKMYEELEKYRSDSATLSKEASASPQSSGIPTRENTPSA
                     FKPIGPGLLKNEIYINALKASFSKSIFNLILEMIFVLENLSRVLKKYESPNQKNNLDE
                     CVKILSHSHSKLKRKIYKLDVCYRDFVNSSFFSQELLNDEESVDIFLFLRYLRNSARQ
                     LVTVIHDCQVLGENIHWRIALPSYPLSRALTRLPKQCVLDEGAGNVLHYFEAKRDVDE
                     IFERVYNTYTSRHKYNKGEEEALRLDSQGGDEKSQNRKNHTISIRAIDHNDFNFHTTQ
                     NPWRFKLWKLSRILSGDECKWTLKITFCMIFLCLPTWLPESYHWYQEFHCWWAPLTFY
                     LLAHRRYSGNWALVMRRLICGIVGIFWGWAANQSRHFGSPYVVCTFAGLIVVPFSINF
                     LVYRNTKSSFTALMCFTIIALEPYSKPNRHYNLTTAGIWKSTWVTGLALIIGILVSIP
                     INWIVWPFRARTELRDSMSSLLAHLGQSYQTVADRYLYRDADDAPTDLTFAFSHIREV
                     RLTQSLEAIRELLKKARHEPIIISNFNPEKYASLINSCQFLLSKIIEARISGAFFEIW
                     DQDFDIETTRALLSLRRDSVSSVIFVFYILSNCFRSKNKIPRYLPNPIMSRKKLYHFI
                     KKFSEMKDQSHSNLNSGGNSMEKNLFKKIYQQKASSSGQQQLPLPSVANSSEIDSEKM
                     HWTEVHGIAFARAFTDISEALFQVESCAKDILGEENF"
     gene            <42700..>43707
                     /gene="PTP1"
                     /locus_tag="YDL230W"
                     /db_xref="GeneID:851368"
     mRNA            <42700..>43707
                     /gene="PTP1"
                     /locus_tag="YDL230W"
                     /product="Ptp1p"
                     /transcript_id="NM_001180290.1"
                     /db_xref="GI:296143144"
                     /db_xref="GeneID:851368"
     CDS             42700..43707
                     /gene="PTP1"
                     /locus_tag="YDL230W"
                     /EC_number="3.1.3.48"
                     /note="Phosphotyrosine-specific protein phosphatase;
                     dephosphorylates a broad range of substrates in vivo,
                     including Fpr3p; localized to the cytoplasm and the
                     mitochondria; proposed to be a negative regulator of
                     filamentation"
                     /codon_start=1
                     /product="Ptp1p"
                     /protein_id="NP_010051.1"
                     /db_xref="GI:6319971"
                     /db_xref="SGD:S000002389"
                     /db_xref="GeneID:851368"
                     /translation="MAAAPWYIRQRDTDLLGKFKFIQNQEDGRLREATNGTVNSRWSL
                     GVSIEPRNDARNRYVNIMPYERNRVHLKTLSGNDYINASYVKVNVPGQSIEPGYYIAT
                     QGPTRKTWDQFWQMCYHNCPLDNIVIVMVTPLVEYNREKCYQYWPRGGVDDTVRIASK
                     WESPGGANDMTQFPSDLKIEFVNVHKVKDYYTVTDIKLTPTDPLVGPVKTVHHFYFDL
                     WKDMNKPEEVVPIMELCAHSHSLNSRGNPIIVHCSAGVGRTGTFIALDHLMHDTLDFK
                     NITERSRHSDRATEEYTRDLIEQIVLQLRSQRMKMVQTKDQFLFIYHAAKYLNSLSVN
                     Q"
     gene            <44065..>45906
                     /gene="SSB1"
                     /locus_tag="YDL229W"
                     /gene_synonym="YG101"
                     /db_xref="GeneID:851369"
     mRNA            <44065..>45906
                     /gene="SSB1"
                     /locus_tag="YDL229W"
                     /gene_synonym="YG101"
                     /product="Hsp70 family ATPase SSB1"
                     /transcript_id="NM_001180289.1"
                     /db_xref="GI:296143145"
                     /db_xref="GeneID:851369"
     CDS             44065..45906
                     /gene="SSB1"
                     /locus_tag="YDL229W"
                     /gene_synonym="YG101"
                     /note="Cytoplasmic ATPase that is a ribosome-associated
                     molecular chaperone; functions with J-protein partner
                     Zuo1p; may be involved in folding of newly-made
                     polypeptide chains; member of the HSP70 family; interacts
                     with phosphatase subunit Reg1p; SSB1 has a paralog, SSB2,
                     that arose from the whole genome duplication"
                     /codon_start=1
                     /product="Hsp70 family ATPase SSB1"
                     /protein_id="NP_010052.1"
                     /db_xref="GI:6319972"
                     /db_xref="SGD:S000002388"
                     /db_xref="GeneID:851369"
                     /translation="MAEGVFQGAIGIDLGTTYSCVATYESSVEIIANEQGNRVTPSFV
                     AFTPEERLIGDAAKNQAALNPRNTVFDAKRLIGRRFDDESVQKDMKTWPFKVIDVDGN
                     PVIEVQYLEETKTFSPQEISAMVLTKMKEIAEAKIGKKVEKAVITVPAYFNDAQRQAT
                     KDAGAISGLNVLRIINEPTAAAIAYGLGAGKSEKERHVLIFDLGGGTFDVSLLHIAGG
                     VYTVKSTSGNTHLGGQDFDTNLLEHFKAEFKKKTGLDISDDARALRRLRTAAERAKRT
                     LSSVTQTTVEVDSLFDGEDFESSLTRARFEDLNAALFKSTLEPVEQVLKDAKISKSQI
                     DEVVLVGGSTRIPKVQKLLSDFFDGKQLEKSINPDEAVAYGAAVQGAILTGQSTSDET
                     KDLLLLDVAPLSLGVGMQGDMFGIVVPRNTTVPTIKRRTFTTCADNQTTVQFPVYQGE
                     RVNCKENTLLGEFDLKNIPMMPAGEPVLEAIFEVDANGILKVTAVEKSTGKSSNITIS
                     NAVGRLSSEEIEKMVNQAEEFKAADEAFAKKHEARQRLESYVASIEQTVTDPVLSSKL
                     KRGSKSKIEAALSDALAALQIEDPSADELRKAEVGLKRVVTKAMSSR"
     rep_origin      45918..46271
                     /note="ARS404;
                     Autonomously Replicating Sequence"
                     /db_xref="SGD:S000114787"
     gene            complement(<46271..>48031)
                     /gene="HO"
                     /locus_tag="YDL227C"
                     /db_xref="GeneID:851371"
     mRNA            complement(<46271..>48031)
                     /gene="HO"
                     /locus_tag="YDL227C"
                     /product="Hop"
                     /transcript_id="NM_001180287.1"
                     /db_xref="GI:296143146"
                     /db_xref="GeneID:851371"
     CDS             complement(46271..48031)
                     /gene="HO"
                     /locus_tag="YDL227C"
                     /note="Site-specific endonuclease; required for gene
                     conversion at the MAT locus (homothallic switching)
                     through the generation of a ds DNA break; expression
                     restricted to mother cells in late G1 as controlled by
                     Swi4p-Swi6p, Swi5p, and Ash1p"
                     /codon_start=1
                     /product="Hop"
                     /protein_id="NP_010054.1"
                     /db_xref="GI:6319974"
                     /db_xref="SGD:S000002386"
                     /db_xref="GeneID:851371"
                     /translation="MLSENTTILMANGEIKDIANVTANSYVMCADGSAARVINVTQGY
                     QKIYNIQQKTKHRAFEGEPGRLDPRRRTVYQRLALQCTAGHKLSVRVPTKPLLEKSGR
                     NATKYKVRWRNLQQCQTLDGRIIIIPKNHHKTFPMTVEGEFAAKRFIEEMERSKGEYF
                     NFDIEVRDLDYLDAQLRISSCIRFGPVLAGNGVLSKFLTGRSDLVTPAVKSMAWMLGL
                     WLGDSTTKEPEISVDSLDPKLMESLRENAKIWGLYLTVCDDHVPLRAKHVRLHYGDGP
                     DENRKTRNLRKNNPFWKAVTILKFKRDLDGEKQIPEFMYGEHIEVREAFLAGLIDSDG
                     YVVKKGEGPESYKIAIQTVYSSIMDGIVHISRSLGMSATVTTRSAREEIIEGRKVQCQ
                     FTYDCNVAGGTTSQNVLSYCRSGHKTREVPPIIKREPVYFSFTDDFQGESTVYGLTIE
                     GHKNFLLGNKIEVKSCRGCCVGEQLKISQKKNLKHCVACPRKGIKYFYKDWSGKNRVC
                     ARCYGRYKFSGHHCINCKYVPEAREVKKAKDKGEKLGITPEGLPVKGPECIKCGGILQ
                     FDAVRGPHKSCGNNAGARIC"
     gene            complement(<51115..>52173)
                     /gene="GCS1"
                     /locus_tag="YDL226C"
                     /db_xref="GeneID:851372"
     mRNA            complement(<51115..>52173)
                     /gene="GCS1"
                     /locus_tag="YDL226C"
                     /product="Gcs1p"
                     /transcript_id="NM_001180286.1"
                     /db_xref="GI:296143147"
                     /db_xref="GeneID:851372"
     CDS             complement(51115..52173)
                     /gene="GCS1"
                     /locus_tag="YDL226C"
                     /note="ADP-ribosylation factor GTPase activating protein
                     (ARF GAP); involved in ER-Golgi transport; required for
                     prospore membrane formation; regulates phospholipase
                     Spo14p; shares functional similarity with Glo3p; GCS1 has
                     a paralog, SPS18, that arose from the whole genome
                     duplication"
                     /codon_start=1
                     /product="Gcs1p"
                     /protein_id="NP_010055.1"
                     /db_xref="GI:6319975"
                     /db_xref="SGD:S000002385"
                     /db_xref="GeneID:851372"
                     /translation="MSDWKVDPDTRRRLLQLQKIGANKKCMDCGAPNPQWATPKFGAF
                     ICLECAGIHRGLGVHISFVRSITMDQFKPEELLRMEKGGNEPLTEWFKSHNIDLSLPQ
                     KVKYDNPVAEDYKEKLTCLCEDRVFEEREHLDFDASKLSATSQTAASATPGVAQSREG
                     TPLENRRSATPANSSNGANFQKEKNEAYFAELGKKNQSRPDHLPPSQGGKYQGFGSTP
                     AKPPQERSAGSSNTLSLENFQADPLGTLSRGWGLFSSAVTKSFEDVNETVIKPHVQQW
                     QSGELSEETKRAAAQFGQKFQETSSYGFQAFSNFTKNFNGNAEDSSTAGNTTHTEYQK
                     IDNNDKKNEQDEDKWDDF"
     gene            <52445..>54100
                     /gene="SHS1"
                     /locus_tag="YDL225W"
                     /gene_synonym="SEP7"
                     /db_xref="GeneID:851373"
     mRNA            <52445..>54100
                     /gene="SHS1"
                     /locus_tag="YDL225W"
                     /gene_synonym="SEP7"
                     /product="septin SHS1"
                     /transcript_id="NM_001180285.1"
                     /db_xref="GI:296143148"
                     /db_xref="GeneID:851373"
     CDS             52445..54100
                     /gene="SHS1"
                     /locus_tag="YDL225W"
                     /gene_synonym="SEP7"
                     /note="Component of the septin ring that is required for
                     cytokinesis; septins are GTP-binding proteins that
                     assemble into rod-like hetero-oligomers that can associate
                     with other rods to form filaments; septin rings at the
                     mother-bud neck act as scaffolds for recruiting cell
                     division factors and as barriers to prevent diffusion of
                     specific proteins; undergoes sumoylation and
                     phosphorylation during mitosis; protein abundance
                     increases in response to DNA replication stress"
                     /codon_start=1
                     /product="septin SHS1"
                     /protein_id="NP_010056.1"
                     /db_xref="GI:6319976"
                     /db_xref="SGD:S000002384"
                     /db_xref="GeneID:851373"
                     /translation="MSTASTPPINLFRRKKEHKRGITYTMLLCGPAGTGKTAFANNLL
                     ETKIFPHKYQYGKSNASISSNPEVKVIAPTKVVSFNSKNGIPSYVSEFDPMRANLEPG
                     ITITSTSLELGGNKDQGKPEMNEDDTVFFNLIMTHGIGENLDDSLCSEEVMSYLEQQF
                     DIVLAEETRIKRNPRFEDTRVHVALYFIEPTGHGLREVDVELMKSISKYTNVLPIITR
                     ADSFTKEELTQFRKNIMFDVERYNVPIYKFEVDPEDDDLESMEENQALASLQPFAIIT
                     SDTRDSEGRYVREYPWGIISIDDDKISDLKVLKNVLFGSHLQEFKDTTQNLLYENYRS
                     EKLSSVANAEEIGPNSTKRQSNAPSLSNFASLISTGQFNSSQTLANNLRADTPRNQVS
                     GNFKENEYEDNGEHDSAENEQEMSPVRQLGREIKQENENLIRSIKTESSPKFLNSPDL
                     PERTKLRNISETVPYVLRHERILARQQKLEELEAQSAKELQKRIQELERKAHELKLRE
                     KLINQNKLNGSSSSINSLQQSTRSQIKKNDTYTDLASIASGRD"
     gene            complement(<54397..>56346)
                     /gene="WHI4"
                     /locus_tag="YDL224C"
                     /db_xref="GeneID:851302"
     mRNA            complement(<54397..>56346)
                     /gene="WHI4"
                     /locus_tag="YDL224C"
                     /product="Whi4p"
                     /transcript_id="NM_001180284.1"
                     /db_xref="GI:296143149"
                     /db_xref="GeneID:851302"
     CDS             complement(54397..56346)
                     /gene="WHI4"
                     /locus_tag="YDL224C"
                     /note="Putative RNA binding protein; regulates the cell
                     size requirement for passage through Start and commitment
                     to cell division; WHI4 has a paralog, WHI3, that arose
                     from the whole genome duplication"
                     /codon_start=1
                     /product="Whi4p"
                     /protein_id="NP_010057.1"
                     /db_xref="GI:6319977"
                     /db_xref="SGD:S000002383"
                     /db_xref="GeneID:851302"
                     /translation="MSLVHNQTNLNESKFLIERAFSSSSETVPLSKEATYPMPTAYSF
                     SAVRSNSETNIKRENPQGFAKEPIMTSMLHNLTMSTGKGNGNDVNSLAPHDVDVGPYC
                     LLLRNLPKDITLRECYCIFSLATGVSSIELKRDDREPFNDNEKVVVVKFGSLSLVTHY
                     ANILNSKSEIFGPSFPFRSHIDVVNEQTQLPVSFQEHVSSGTTNSSPKNYQLSSSAQN
                     EIQNQSFNTISYGKTSSSPLGPSAAKPRPSLLSERSLRFSFNDPFGLETISQRKESVP
                     FLRNSISQHDLSNVTTTPVPAGMPPQKDAGKSLLLLEKDEINESIWNGDELVNDVGNS
                     SFGASLQEPPMSSTPVMEWNASSTANIPLFQLSSQENHQSNLLPPSHHSISQDVPHIQ
                     SQPNLNNSGVIHSATSLPHYHLLNQINASTKTQSIQQSVSNVPSNLDLNLQTENGHPQ
                     SSAPNGSSIFNNQKVNQGFLVSEQDTSTISRQKECSSTASASAFSKNNETNVAGSTTI
                     SQADLSLLAKVPPPANPADQNPPCNTLYVGNLPPDATEQELRQLFSNQQGFRRLSFRN
                     KMNSHGHGNGHGHGPICFVEFEDVSFATRALAELYGSQLPHPRPSLNNKGGIRLSFSK
                     NPLGVRGSNSRSKSGYSFNGSYGKS"
     gene            complement(<57265..>60405)
                     /gene="HBT1"
                     /locus_tag="YDL223C"
                     /db_xref="GeneID:851303"
     mRNA            complement(<57265..>60405)
                     /gene="HBT1"
                     /locus_tag="YDL223C"
                     /product="Hbt1p"
                     /transcript_id="NM_001180283.1"
                     /db_xref="GI:296143150"
                     /db_xref="GeneID:851303"
     CDS             complement(57265..60405)
                     /gene="HBT1"
                     /locus_tag="YDL223C"
                     /note="Shmoo tip protein, substrate of Hub1p
                     ubiquitin-like protein; mutants are defective for mating
                     projection formation, thereby implicating Hbt1p in
                     polarized cell morphogenesis; HBT1 has a paralog, YNL195C,
                     that arose from the whole genome duplication"
                     /codon_start=1
                     /product="Hbt1p"
                     /protein_id="NP_010058.1"
                     /db_xref="GI:6319978"
                     /db_xref="SGD:S000002382"
                     /db_xref="GeneID:851303"
                     /translation="MNMNESISKDGQGEEEQNNFSFGGKPGSYDSNSDSAQRKKSFST
                     TKPTEYNLPKEQPESTSKNLETKAKNILLPWRKKHNKDSETPHEDTEADANRRANVTS
                     DVNPVSADTKSSSGPNATITTHGYSYVKTTTPAATSEQSKVKTSPPTSHEHSNIKASP
                     TAHRHSKGDAGHPSIATTHNHSTSKAATSPVTHTHGHSSATTSPVTHTHGHASVKTTS
                     PTNTHEHSKANTGPSATATTHGHINVKTTHPVSHGHSGSSTGPKSTAAAQDHSSTKTN
                     PSVTHGHTSVKDNSSATKGYSNTDSNSDRDVIPGSFRGMTGTDVNPVDPSVYTSTGPK
                     SNVSSGMNAVDPSVYTDTSSKSADRRKYSGNTATGPPQDTIKEIAQNVKMDESEQTGL
                     KNDQVSGSDAIQQQTMEPEPKAAVGTSGFVSQQPSYHDSNKNIQHPEKNKVDNKNISE
                     RAAEKFNIERDDILESADDYQQKNIKSKTDSNWGPIEYSSSAGKNKNLQDVVIPSSMK
                     EKFDSGTSGSQNMPKAGTELGHMKYNDNGRDNLQYVAGSQAGSQNTNNNIDMSPRHEA
                     EWSGLSNDATTRNNVVSPAMKDEDMNEDSTKPHQYGLDYLDDVEDYHENDIDDYSNAK
                     KNDLYSKKAYQGKPSDYNYEQREKIPGTFEPDTLSKSVQKQDEDPLSPRQTTNRAGME
                     TARDESLGNYEYSNTSGNKKLSDLSKNKSGPTPTRSNFIDQIEPRRAKTTQDIASDAK
                     DFTNNPETGTTGNVDTTGRMGAKSKTFSSNPFDDSKNTDTHLENANVAAFDNSRSGDT
                     TYSKSGDAETAAYDNIKNADPTYAKSQDITGMTHDQEPSSEQKASYGSGGNSQNQEYS
                     SDDNIDVNKNAKVLEEDAPGYKREVDLKNKRRTDLGGADASNAYAAEVGNFPSLIDPH
                     VPTYGFKDTNTSSSQKPSEGTYPETTSYSIHNETTSQGRKVSVGSMGSGKSKHHHNHH
                     RHSRQNSSKGSDYDYNNSTHSAEHTPRHHQYGSDEGEQDYHDDEQGEEQAGKQSFMGR
                     VRKSISGGTFGFRSEI"
     gene            complement(<60872..>61801)
                     /gene="FMP45"
                     /locus_tag="YDL222C"
                     /db_xref="GeneID:851304"
     mRNA            complement(<60872..>61801)
                     /gene="FMP45"
                     /locus_tag="YDL222C"
                     /product="Fmp45p"
                     /transcript_id="NM_001180282.1"
                     /db_xref="GI:296143151"
                     /db_xref="GeneID:851304"
     CDS             complement(60872..61801)
                     /gene="FMP45"
                     /locus_tag="YDL222C"
                     /note="Integral membrane protein localized to
                     mitochondria; required for sporulation and maintaining
                     sphingolipid content; similar to SUR7; FMP45 has a
                     paralog, YNL194C, that arose from the whole genome
                     duplication"
                     /codon_start=1
                     /product="Fmp45p"
                     /protein_id="NP_010059.1"
                     /db_xref="GI:6319979"
                     /db_xref="SGD:S000002381"
                     /db_xref="GeneID:851304"
                     /translation="MIFKRFVNLLVFLFLLGAGLLTFFLILSGGRESGTLKNFYWLQA
                     DTNGFNSAPSTTRWYNYNWCGYEDGQLANCSSRAPAKPFSPRDNFGNSVNLPSSFRNN
                     RDTYYYLSRVGWAMLLISLFFIVLALVPGFLATFLPFKAVPVLYCVLSWLAFFFIILA
                     ACLYTGCYVKARKTFRNSGRSARLGPKNFAFIWTSVFLMLVNAIWSTIFSATHKAHST
                     YSDHDMYAQYESPSVDTGAQMEKSTYNSGATDGAGPITAAPVVGQPQPTTTTTPAGNG
                     KFFQKLKTRKQVPSAELEPAGDGGLAGPVTVRD"
     gene            complement(<62244..>65018)
                     /gene="CDC13"
                     /locus_tag="YDL220C"
                     /gene_synonym="EST4"
                     /db_xref="GeneID:851306"
     mRNA            complement(<62244..>65018)
                     /gene="CDC13"
                     /locus_tag="YDL220C"
                     /gene_synonym="EST4"
                     /product="Cdc13p"
                     /transcript_id="NM_001180280.1"
                     /db_xref="GI:296143152"
                     /db_xref="GeneID:851306"
     CDS             complement(62244..65018)
                     /gene="CDC13"
                     /locus_tag="YDL220C"
                     /gene_synonym="EST4"
                     /note="Single stranded DNA-binding protein found at TG1-3
                     telomere G-tails; key roles in regulation of telomerase,
                     telomere end protection, conventional telomere
                     replication; regulates telomere replication through
                     recruitment of specific sub-complexes, essential function
                     is telomere capping; forms homodimer via N-terminus;
                     disruption of dimerization leads to short telomeres;
                     autophagy and proteasome are involved in Cdc13p
                     degradation; differentially phosphorylated through cell
                     cycle"
                     /codon_start=1
                     /product="Cdc13p"
                     /protein_id="NP_010061.1"
                     /db_xref="GI:6319981"
                     /db_xref="SGD:S000002379"
                     /db_xref="GeneID:851306"
                     /translation="MDTLEEPECPPHKNRIFVSSSKDFEGYPSKAIVPVQFVALLTSI
                     HLTETKCLLGFSNFERRGDQSQEDQYLIKLKFKDRGSERLARITISLLCQYFDIELPD
                     LDSDSGASPTVILRDIHLERLCFSSCKALYVSKHGNYTLFLEDIKPLDLVSVISTIST
                     KSTNSSKHSSSELISECDLNNSLVDIFNNLIEMNRDEKNRFKFVKLIHYDIELKKFVQ
                     DQQKVLSQKSKAAAINPFFVPNRLGIPYIESQNEFNSQLMTLNVDEPTTDISNMGEEM
                     HDSADPIEDSDSSTTSSTGKYFSSKSYIQSQTPERKTSVPNNWHDDDSGSKRKRKLSF
                     HSPNASSIRKAISYEQLSLASVGSVERLEGKIVGMNPPQFASINEFKYCTLKLYFTQL
                     LPNVPDKVLVPGVNCIEIVIPTRERICELFGVLNCQSDKISDILLLEKPDRISVEVER
                     ILWDNDKTASPGMAVWSLKNISTDTQAQAQVQVPAQSSASIDPSRTRMSKMARKDPTI
                     EFCQLGLDTFETKYITMFGMLVSCSFDKPAFISFVFSDFTKNDIVQNYLYDRYLIDYE
                     NKLELNEGFKAIMYKNQFETFDSKLRKIFNNGLRDLQNGRDENLSQYGIVCKMNIKVK
                     MYNGKLNAIVRECEPVPHSQISSIASPSQCEHLRLFYQRAFKRIGESAISRYFEEYRR
                     FFPIHRNGSHLAKLRFDEVKHEPKKSPTTPALAEHIPDLNADVSSFDVKFTDISSLLD
                     SSARLPRPQQTHKSNTLYSCEGRIIAIEYHASDLCFHITNELPLLQTRGLAPERVLQL
                     HIITSKNFAYFFNRSSAYLQRQPLEEKYTQLAQFLGHSFKFNITSSLTLFPDTTVALQ
                     IWCPIECTFRELQQQLAHPKVAAAPDSGSLDCAINATVNPLRLLAAQNGVTVKKEEDN
                     DDDAGAVPTS"
     gene            <65242..>65765
                     /gene="DTD1"
                     /locus_tag="YDL219W"
                     /db_xref="GeneID:851307"
     mRNA            join(<65242..65306,65378..>65765)
                     /gene="DTD1"
                     /locus_tag="YDL219W"
                     /product="Dtd1p"
                     /transcript_id="NM_001180279.1"
                     /db_xref="GI:296143153"
                     /db_xref="GeneID:851307"
     CDS             join(65242..65306,65378..65765)
                     /gene="DTD1"
                     /locus_tag="YDL219W"
                     /EC_number="3.1.-.-"
                     /note="D-Tyr-tRNA(Tyr) deacylase; functions in protein
                     translation, may affect nonsense suppression via
                     alteration of the protein synthesis machinery; ubiquitous
                     among eukaryotes"
                     /codon_start=1
                     /product="Dtd1p"
                     /protein_id="NP_010062.1"
                     /db_xref="GI:6319982"
                     /db_xref="SGD:S000002378"
                     /db_xref="GeneID:851307"
                     /translation="MKIVLQKVSQASVVVDSKVISSIKHGYMLLVGISIDDSMAEIDK
                     LSKKVLSLRIFEDESRNLWKKNIKEANGEILSVSQFTLMAKTKKGTKPDFHLAQKGHI
                     AKELYEEFLKLLRSDLGEEKVKDGEFGAMMSCSLTNEGPVTIILDSDQ"
     gene            <66493..>67446
                     /locus_tag="YDL218W"
                     /db_xref="GeneID:851308"
     mRNA            <66493..>67446
                     /locus_tag="YDL218W"
                     /product="hypothetical protein"
                     /transcript_id="NM_001180278.1"
                     /db_xref="GI:296143154"
                     /db_xref="GeneID:851308"
     CDS             66493..67446
                     /locus_tag="YDL218W"
                     /note="hypothetical protein; YDL218W transcription is
                     regulated by Azf1p and induced by starvation and aerobic
                     conditions; expression also induced in cells treated with
                     the mycotoxin patulin"
                     /codon_start=1
                     /product="hypothetical protein"
                     /protein_id="NP_010063.1"
                     /db_xref="GI:6319983"
                     /db_xref="SGD:S000002377"
                     /db_xref="GeneID:851308"
                     /translation="MKRVTGVFLTLLRFSQFASSVLVMSLLAYAIHAYGNRGNKKTNF
                     TLATGVISVFYLIALGILCLALPTLIYIGMYFCAELIVCMLWLAAFVVLAKAQGERSC
                     SNTNADGLYYNPYSGQYTADSHRRACNSSQAAIAFSGLCFVLFLISVILLGINVLTPI
                     RKRYQTQGMWRSGASMGTKLHRWSGLALSEPFEETAAYDNTNVRTGDVEAGAGDNAAY
                     TSEPNGDARYATNDPNGQYHTTTTNTRYTTTTADPKTRYTTNDRNPGSANVANSAVDQ
                     HAYSTDESGDRSYQEKVTEGAHSGAMSGSTAEPNRNVNQMP"
     gene            complement(<67983..>68606)
                     /gene="TIM22"
                     /locus_tag="YDL217C"
                     /db_xref="GeneID:851309"
     mRNA            complement(<67983..>68606)
                     /gene="TIM22"
                     /locus_tag="YDL217C"
                     /product="Tim22p"
                     /transcript_id="NM_001180277.1"
                     /db_xref="GI:296143155"
                     /db_xref="GeneID:851309"
     CDS             complement(67983..68606)
                     /gene="TIM22"
                     /locus_tag="YDL217C"
                     /note="Essential core component of the mitochondrial TIM22
                     complex; involved in insertion of polytopic proteins into
                     the inner membrane; forms the channel through which
                     proteins are imported"
                     /codon_start=1
                     /product="Tim22p"
                     /protein_id="NP_010064.1"
                     /db_xref="GI:6319984"
                     /db_xref="SGD:S000002376"
                     /db_xref="GeneID:851309"
                     /translation="MVYTGFGLEQISPAQKKPYNELTPEEQGERGAEMIMNFMTSCPG
                     KSVVSGVTGFALGGVLGLFMASMAYDTPLHTPTPANTAATATAGNIGVGGISRTVQQI
                     SDLPFRQQMKLQFTDMGKKSYSSAKNFGYIGMIYAGVECVIESLRAKNDIYNGVTAGF
                     FTGAGLAYKAGPQAALMGGAGFAAFSAAIDLYMKSEDGRPPQNDFKE"
     gene            complement(<68997..>70319)
                     /gene="RRI1"
                     /locus_tag="YDL216C"
                     /gene_synonym="CSN5; JAB1"
                     /db_xref="GeneID:851310"
     mRNA            complement(<68997..>70319)
                     /gene="RRI1"
                     /locus_tag="YDL216C"
                     /gene_synonym="CSN5; JAB1"
                     /product="Rri1p"
                     /transcript_id="NM_001180276.1"
                     /db_xref="GI:296143156"
                     /db_xref="GeneID:851310"
     CDS             complement(68997..70319)
                     /gene="RRI1"
                     /locus_tag="YDL216C"
                     /gene_synonym="CSN5; JAB1"
                     /EC_number="3.4.-.-"
                     /note="Catalytic subunit of the COP9 signalosome (CSN)
                     complex; acts as an isopeptidase in cleaving the
                     ubiquitin-like protein Nedd8 from SCF ubiquitin ligases;
                     metalloendopeptidase involved in the adaptation to
                     pheromone signaling"
                     /codon_start=1
                     /product="Rri1p"
                     /protein_id="NP_010065.2"
                     /db_xref="GI:93117369"
                     /db_xref="SGD:S000002375"
                     /db_xref="GeneID:851310"
                     /translation="MSLSNKTVKELRQLLKERYTVEDELTESIALSSMRFKPSQEPEF
                     HALSQSSLLKTKLKQQSSTDIPSYTHVLISKLSCEKITHYAVRGGNIEIMGILMGFTL
                     KDNIVVMDCFNLPVVGTETRVNAQLESYEYMVQYIDEMYNHNDGGDGRDYKGAKLNVV
                     GWFHSHPGYDCWLSNIDIQTQDLNQRFQDPYVAIVVDPLKSLEDKILRMGAFRTIESK
                     SDDNSATSYYELETIIFDSELNRALFETKLNLHCVIEDDESEQISLNRLIDSMKQYSY
                     LMDSKNVRTRIKLATTSERVSNENKKNIDYQNRSTRSQFCLNTQRGDSTETSSFGSMF
                     SGDNTSDVDMEDRNLTEFDSTDTSLCINGEPSIHVNRVERSSRSTDNFHNSKKRMNSN
                     QERCHDEGNDMLQRNVLETDYARAKNRILASKIKQYERLRFYKDTFTL"
     gene            complement(<70640..>73918)
                     /gene="GDH2"
                     /locus_tag="YDL215C"
                     /db_xref="GeneID:851311"
     mRNA            complement(<70640..>73918)
                     /gene="GDH2"
                     /locus_tag="YDL215C"
                     /product="glutamate dehydrogenase (NAD(+))"
                     /transcript_id="NM_001180275.1"
                     /db_xref="GI:296143157"
                     /db_xref="GeneID:851311"
     CDS             complement(70640..73918)
                     /gene="GDH2"
                     /locus_tag="YDL215C"
                     /EC_number="1.4.1.2"
                     /note="NAD(+)-dependent glutamate dehydrogenase; degrades
                     glutamate to ammonia and alpha-ketoglutarate; expression
                     sensitive to nitrogen catabolite repression and
                     intracellular ammonia levels; genetically interacts with
                     GDH3 by suppressing stress-induced apoptosis"
                     /codon_start=1
                     /product="glutamate dehydrogenase (NAD(+))"
                     /protein_id="NP_010066.1"
                     /db_xref="GI:6319986"
                     /db_xref="SGD:S000002374"
                     /db_xref="GeneID:851311"
                     /translation="MLFDNKNRGALNSLNTPDIASLSISSMSDYHVFDFPGKDLQREE
                     VIDLLDQQGFIPDDLIEQEVDWFYNSLGIDDLFFSRESPQLISNIIHSLYASKLDFFA
                     KSKFNGIQPRLFSIKNKIITNDNHAIFMESNTGVSISDSQQKNFKFASDAVGNDTLEH
                     GKDTIKKNRIEMDDSCPPYELDSEIDDLFLDNKSQKNCRLVSFWAPESELKLTFVYES
                     VYPNDDPAGVDISSQDLLKGDIESISDKTMYKVSSNENKKLYGLLLKLVKEREGPVIK
                     TTRSVENKDEIRLLVAYKRFTTKRYYSALNSLFHYYKLKPSKFYLESFNVKDDDIIIF
                     SVYLNENQQLEDVLLHDVEAALKQVEREASLLYAIPNNSFHEVYQRRQFSPKEAIYAH
                     IGAIFINHFVNRLGSDYQNLLSQITIKRNDTTLLEIVENLKRKLRNETLTQQTIINIM
                     SKHYTIISKLYKNFAQIHYYHNSTKDMEKTLSFQRLEKVEPFKNDQEFEAYLNKFIPN
                     DSPDLLILKTLNIFNKSILKTNFFITRKVAISFRLDPSLVMTKFEYPETPYGIFFVVG
                     NTFKGFHIRFRDIARGGIRIVCSRNQDIYDLNSKNVIDENYQLASTQQRKNKDIPEGG
                     SKGVILLNPGLVEHDQTFVAFSQYVDAMIDILINDPLKENYVNLLPKEEILFFGPDEG
                     TAGFVDWATNHARVRNCPWWKSFLTGKSPSLGGIPHDEYGMTSLGVRAYVNKIYETLN
                     LTNSTVYKFQTGGPDGDLGSNEILLSSPNECYLAILDGSGVLCDPKGLDKDELCRLAH
                     ERKMISDFDTSKLSNNGFFVSVDAMDIMLPNGTIVANGTTFRNTFHTQIFKFVDHVDI
                     FVPCGGRPNSITLNNLHYFVDEKTGKCKIPYIVEGANLFITQPAKNALEEHGCILFKD
                     ASANKGGVTSSSMEVLASLALNDNDFVHKFIGDVSGERSALYKSYVVEVQSRIQKNAE
                     LEFGQLWNLNQLNGTHISEISNQLSFTINKLNDDLVASQELWLNDLKLRNYLLLDKII
                     PKILIDVAGPQSVLENIPESYLKVLLSSYLSSTFVYQNGIDVNIGKFLEFIGGLKREA
                     EASA"
     gene            complement(<74446..>76545)
                     /gene="PRR2"
                     /locus_tag="YDL214C"
                     /db_xref="GeneID:851312"
     mRNA            complement(<74446..>76545)
                     /gene="PRR2"
                     /locus_tag="YDL214C"
                     /product="Prr2p"
                     /transcript_id="NM_001180274.1"
                     /db_xref="GI:296143158"
                     /db_xref="GeneID:851312"
     CDS             complement(74446..76545)
                     /gene="PRR2"
                     /locus_tag="YDL214C"
                     /EC_number="2.7.11.1"
                     /note="Serine/threonine protein kinase; inhibits pheromone
                     induced signalling downstream of MAPK, possibly at the
                     level of the Ste12p transcription factor; mutant has
                     increased aneuploidy tolerance; PRR2 has a paralog, NPR1,
                     that arose from the whole genome duplication"
                     /codon_start=1
                     /product="Prr2p"
                     /protein_id="NP_010067.1"
                     /db_xref="GI:6319987"
                     /db_xref="SGD:S000002373"
                     /db_xref="GeneID:851312"
                     /translation="MSLSRILRYNQRNNKTTASLTAEHAYSDNWAYSVSLGDPTSVGV
                     NMAAKTGEALNKSYDSVFSSLPVADSVPRTDFTASSRDDENTDVQKLTTSWMEKIDTK
                     MPENISKIDSNIISSPMVSKVEARFIVPKGRLRKNSTDFTSSFSNSLSLPKSYGKLIF
                     FTSKKNSSSTKKNLANDISDNKHNNNSSNTIGHNIPVTTATATCDEIACTSTEHEYNV
                     YEEERMFTTRVYSLEDSVSSLSTNPLDDTYSEAVQVNTRHIEDTESTAHIRKHSYTTS
                     LSSIKRLFKITSFSNNNSNSCDHQESTVADDCAISSSLKETTSSPVSTGSFSLMIENE
                     DSDRDQIIQALYSNIEASTDLVSRKYRDLDVVLGEGSGGKVKLVQRVLDNKVFALKEY
                     RSKKKRESERKYIKNIISEYCIASTLKNPNICETLEILYEKGKIFQILEYCEYDLFSL
                     VMSEKMHYEEICCLFKQLINGVKYLHDIGLSHRDLKLDNCVVTRRGILKLIDFGASSV
                     FHYPLSSQMIEANGIVGSDPYLSPEVFYFNEYDPRALDVWSVGIIFFCMITRRFPWKY
                     PKVKDVQFKAFCSGRGVSSFKDLVTRPATDDSNNYDNDGYEEGVIDMGPNFILHRLPE
                     ETHKIMRRILEVSPFRRITINGILQDGWIKEIETCQVVGAASPNEASLRIINKGNHIH
                     TNIDQRYAHIGGLHQRT"
     gene            complement(<77289..>77966)
                     /gene="NOP6"
                     /locus_tag="YDL213C"
                     /db_xref="GeneID:851313"
     mRNA            complement(<77289..>77966)
                     /gene="NOP6"
                     /locus_tag="YDL213C"
                     /product="Nop6p"
                     /transcript_id="NM_001180273.1"
                     /db_xref="GI:296143159"
                     /db_xref="GeneID:851313"
     CDS             complement(77289..77966)
                     /gene="NOP6"
                     /locus_tag="YDL213C"
                     /note="rRNA-binding protein required for 40S ribosomal
                     subunit biogenesis; contains an RNA recognition motif
                     (RRM); hydrophilin essential to overcome the stress of the
                     desiccation-rehydration process; NOP6 may be a
                     fungal-specific gene as no homologs have been yet
                     identified in higher eukaryotes"
                     /codon_start=1
                     /product="Nop6p"
                     /protein_id="NP_010068.1"
                     /db_xref="GI:6319988"
                     /db_xref="SGD:S000002372"
                     /db_xref="GeneID:851313"
                     /translation="MGSEEDKKLTKKQLKAQQFRKSKEEKDQEKDVKKEQAPEGKRPN
                     SAAGNDGEEPVKKKRKTRRGRGGKGKNGKKGNRFIVFVGSLPRDITAVELQNHFKNSS
                     PDQIRLRADKGIAFLEFDADKDRTGIQRRMDIALLQHGTLLKEKKINVELTVGGGGNS
                     QERLEKLKNKNIKLDEERKERLTKMINDGNQKKIAKTTATAAQTSGTDNKPVPAGIHP
                     DRAKLLK"
     gene            <78426..>79058
                     /gene="SHR3"
                     /locus_tag="YDL212W"
                     /gene_synonym="APF1"
                     /db_xref="GeneID:851314"
     mRNA            <78426..>79058
                     /gene="SHR3"
                     /locus_tag="YDL212W"
                     /gene_synonym="APF1"
                     /product="Shr3p"
                     /transcript_id="NM_001180272.1"
                     /db_xref="GI:296143160"
                     /db_xref="GeneID:851314"
     CDS             78426..79058
                     /gene="SHR3"
                     /locus_tag="YDL212W"
                     /gene_synonym="APF1"
                     /note="Endoplasmic reticulum packaging chaperone; required
                     for incorporation of amino acid permeases into COPII
                     coated vesicles for transport to the cell surface"
                     /codon_start=1
                     /product="Shr3p"
                     /protein_id="NP_010069.1"
                     /db_xref="GI:6319989"
                     /db_xref="SGD:S000002371"
                     /db_xref="GeneID:851314"
                     /translation="MFSYSDFCSIGTAMILSATTFLMGVFFSNMPYDYHLLFNPNSTQ
                     EHFDLALRHYQILHETPLPVIVTLCVVAGIGLVGGTIKVFKPNPELQMFEYCSLGLYV
                     LAICVFLTNVKTGIDCSVSHNWGEVTENQGLAVIASSNIILLVMFAGVIILQIGLWYS
                     NWDLQKRLKEFYAQEEREAANAGKKTEKVDNAKKNDNKSKGAQKRKNAKK"
     gene            complement(<79294..>80412)
                     /locus_tag="YDL211C"
                     /db_xref="GeneID:851315"
     mRNA            complement(<79294..>80412)
                     /locus_tag="YDL211C"
                     /product="hypothetical protein"
                     /transcript_id="NM_001180271.1"
                     /db_xref="GI:296143161"
                     /db_xref="GeneID:851315"
     CDS             complement(79294..80412)
                     /locus_tag="YDL211C"
                     /note="hypothetical protein; green fluorescent protein
                     (GFP)-fusion protein localizes to the vacuole; YDL211C has
                     a paralog, TDA7, that arose from the whole genome
                     duplication"
                     /codon_start=1
                     /product="hypothetical protein"
                     /protein_id="NP_010070.1"
                     /db_xref="GI:6319990"
                     /db_xref="SGD:S000002370"
                     /db_xref="GeneID:851315"
                     /translation="MLLNVTSSQYISTPQSRSLSEIDTSETASLSSATDHIFALSTEV
                     VSSITTNLIEGLESSIQVPISTAYGTTSFRNNTSSPQYLVSNCTSSVQSNITIDRGLL
                     STLKTFTTSQVPTIEPSTTKLTTPLSTTFTSTSTSEIYSVFTSENSVYIIYDQEYKFT
                     ERSTTFNTHFPQTTVLQESNPPLTFTIPSNTITGDAKLYQYLSGALNTQDTSDANNRR
                     TGVIVGSTVGVVIGVVIVIFIGFIIIRNRRNVKNHSKKGFSHDIGKRVSCDEVTETEA
                     PSNPFLNVLNYKVTTNGEGKRDSFENGRDLHRASSSDGIYIAHPYYGMADHESGRFSY
                     VSSYNESAESSIEETSSSASTITRPNIQQTNSFLREII"
     gene            83548..83618
                     /locus_tag="tG(GCC)D1"
                     /db_xref="GeneID:851316"
     tRNA            83548..83618
                     /locus_tag="tG(GCC)D1"
                     /product="tRNA-Gly"
                     /note="Glycine tRNA (tRNA-Gly), predicted by tRNAscan-SE
                     analysis"
                     /db_xref="SGD:S000006576"
                     /db_xref="GeneID:851316"
     gene            <84270..>85985
                     /gene="UGA4"
                     /locus_tag="YDL210W"
                     /db_xref="GeneID:851317"
     mRNA            <84270..>85985
                     /gene="UGA4"
                     /locus_tag="YDL210W"
                     /product="Uga4p"
                     /transcript_id="NM_001180270.1"
                     /db_xref="GI:296143162"
                     /db_xref="GeneID:851317"
     CDS             84270..85985
                     /gene="UGA4"
                     /locus_tag="YDL210W"
                     /note="GABA (gamma-aminobutyrate) permease; serves as a
                     GABA transport protein involved in the utilization of GABA
                     as a nitrogen source; catalyzes the transport of
                     putrescine and delta-aminolevulinic acid (ALA); localized
                     to the vacuolar membrane"
                     /codon_start=1
                     /product="Uga4p"
                     /protein_id="NP_010071.1"
                     /db_xref="GI:6319991"
                     /db_xref="SGD:S000002369"
                     /db_xref="GeneID:851317"
                     /translation="MSMSSKNENKISVEQRISTDIGQAYQLQGLGSNLRSIRSKTGAG
                     EVNYIDAAKSVNDNQLLAEIGYKQELKRQFSTLQVFGIAFSIMGLLPSIASVMGGGLG
                     GGPATLVWGWFVAAFFILLVGITMAEHASSIPTAGGLYYWTYYYAPEGYKEIISFIIG
                     CSNSLALAAGVCSIDYGLAEEIAAAVTLTKDGNFEVTSGKLYGIFAGAVVVMCICTCV
                     ASGAIARLQTLSIFANLFIIVLLFIALPIGTKHRMGGFNDGDFIFGKYENLSDWNNGW
                     QFCLAGFMPAVWTIGSFDSCVHQSEEAKDAKKSVPIGIISSIAVCWILGWLIIICLMA
                     CINPDIDSVLDSKYGFALAQIIYDSLGKKWAIAFMSLIAFCQFLMGASITTAVSRQVW
                     AFSRDNGLPLSKYIKRVDSKYSVPFFAILAACVGSLILGLLCLIDDAATDALFSLAVA
                     GNNLAWSTPTVFRLTSGRDLFRPGPFYLGKIWSPIVAWTGVAFQLFIIILVMFPSQQH
                     GITKSTMNYACVIGPGIWILAGIYYKVYKKKYYHGPATNLSDDDYTEAVGADVIDTIM
                     SKQEP"
     rep_origin      85945..86176
                     /note="ARS405;
                     Autonomously Replicating Sequence"
                     /db_xref="SGD:S000118428"
     gene            complement(<86207..>87226)
                     /gene="CWC2"
                     /locus_tag="YDL209C"
                     /gene_synonym="NTC40"
                     /db_xref="GeneID:851318"
     mRNA            complement(<86207..>87226)
                     /gene="CWC2"
                     /locus_tag="YDL209C"
                     /gene_synonym="NTC40"
                     /product="Cwc2p"
                     /transcript_id="NM_001180269.1"
                     /db_xref="GI:296143163"
                     /db_xref="GeneID:851318"
     CDS             complement(86207..87226)
                     /gene="CWC2"
                     /locus_tag="YDL209C"
                     /gene_synonym="NTC40"
                     /note="Member of the NineTeen Complex (NTC); this complex
                     contains Prp19p and stabilizes U6 snRNA in catalytic forms
                     of the spliceosome containing U2, U5, and U6 snRNAs; binds
                     directly to U6 snRNA; similar to S. pombe Cwf2"
                     /codon_start=1
                     /product="Cwc2p"
                     /protein_id="NP_010072.1"
                     /db_xref="GI:6319992"
                     /db_xref="SGD:S000002368"
                     /db_xref="GeneID:851318"
                     /translation="MTSWRDKSAKVQVKESELPSSIPAQTGLTFNIWYNKWSQGFAGN
                     TRFVSPFALQPQLHSGKTRGDNDGQLFFCLFFAKGMCCLGPKCEYLHHIPDEEDIGKL
                     ALRTEVLDCFGREKFADYREDMGGIGSFRKKNKTLYVGGIDGALNSKHLKPAQIESRI
                     RFVFSRLGDIDRIRYVESKNCGFVKFKYQANAEFAKEAMSNQTLLLPSDKEWDDRREG
                     TGLLVKWANEDPDPAAQKRLQEELKLESLNMMVHLINNNTNSAGTEVNNKNNERLDRT
                     FPEASVDNVKKRLLPLDNGMESDDFIEKLKKVKKNISRENISSKPSVGKLGGPLLDYL
                     SSDED"
     gene            <87512..>87982
                     /gene="NHP2"
                     /locus_tag="YDL208W"
                     /db_xref="GeneID:851319"
     mRNA            <87512..>87982
                     /gene="NHP2"
                     /locus_tag="YDL208W"
                     /product="snoRNA-binding protein NHP2"
                     /transcript_id="NM_001180268.1"
                     /db_xref="GI:296143164"
                     /db_xref="GeneID:851319"
     CDS             87512..87982
                     /gene="NHP2"
                     /locus_tag="YDL208W"
                     /note="Protein related to mammalian high mobility group
                     (HMG) proteins; nuclear protein; essential for function of
                     H/ACA-type snoRNPs, which are involved in 18S rRNA
                     processing"
                     /codon_start=1
                     /product="snoRNA-binding protein NHP2"
                     /protein_id="NP_010073.2"
                     /db_xref="GI:82795243"
                     /db_xref="SGD:S000002367"
                     /db_xref="GeneID:851319"
                     /translation="MGKDNKEHKESKESKTVDNYEARMPAVLPFAKPLASKKLNKKVL
                     KTVKKASKAKNVKRGVKEVVKALRKGEKGLVVIAGDISPADVISHIPVLCEDHSVPYI
                     FIPSKQDLGAAGATKRPTSVVFIVPGSNKKKDGKNKEEEYKESFNEVVKEVQAL"
     gene            <88248..>89864
                     /gene="GLE1"
                     /locus_tag="YDL207W"
                     /gene_synonym="BRR3; NLE2; RSS1"
                     /db_xref="GeneID:851320"
     mRNA            <88248..>89864
                     /gene="GLE1"
                     /locus_tag="YDL207W"
                     /gene_synonym="BRR3; NLE2; RSS1"
                     /product="Gle1p"
                     /transcript_id="NM_001180267.1"
                     /db_xref="GI:296143165"
                     /db_xref="GeneID:851320"
     CDS             88248..89864
                     /gene="GLE1"
                     /locus_tag="YDL207W"
                     /gene_synonym="BRR3; NLE2; RSS1"
                     /note="Cytoplasmic nucleoporin required for polyadenylated
                     mRNA export; contains a nuclear export signal; when bound
                     to inositol hexakisphosphate (IP6), functions as an
                     activator for the Dbp5p ATPase activity at the nuclear
                     pore complex during mRNA export; mediates translation
                     initiation; required for efficient translation
                     termination"
                     /codon_start=1
                     /product="Gle1p"
                     /protein_id="NP_010074.1"
                     /db_xref="GI:6319994"
                     /db_xref="SGD:S000002366"
                     /db_xref="GeneID:851320"
                     /translation="MRFVFDEVFNSDTDSPEFEETCSTTSSTSSQCPTPEPSPAIKLP
                     SFTKVGTKKLVNESVVILDPALENALRDLNLQSKLIPINEPIVAASSIIVPHSTNMPL
                     PRASHSSLLDNAKNSNATAPLLEAIEESFQRKMQNLVLANQKEIQSIRENKRRVEEQR
                     KRKEEEERKRKEAEEKAKREQELLRQKKDEEERKRKEAEAKLAQQKQEEERKKIEEQN
                     EKERQLKKEHEAKLLQQKDKLGKAVTNFDKISKMFWHYKDKIAQIKQDIVLPIKKADV
                     NVRNLLSRHKRKINPKFGQLTNSNQQLFKIQNELTQLINDTKGDSLAYHWILNFIAKA
                     VVHQAETEVRVKPESALPLGKLTLYLLVQFPELQELFMARLVKKCPFVIGFTCEIDTE
                     KGRQNMGWKRNNENKWEDNTSYDERMGGILSLFAIITRLQLPQEFITTTSHPFPIALS
                     WHILARICNTPLNLITNTHFVILGSWWDAAAVQFLQAYGNQASKLLILIGEELTSRMA
                     EKKYVGAARLRILLEAWQNNNMESFPEMSP"
     gene            <90176..>92464
                     /locus_tag="YDL206W"
                     /db_xref="GeneID:851321"
     mRNA            <90176..>92464
                     /locus_tag="YDL206W"
                     /product="hypothetical protein"
                     /transcript_id="NM_001180266.1"
                     /db_xref="GI:296143166"
                     /db_xref="GeneID:851321"
     CDS             90176..92464
                     /locus_tag="YDL206W"
                     /note="hypothetical protein; YDL206W is not an essential
                     protein"
                     /codon_start=1
                     /product="hypothetical protein"
                     /protein_id="NP_010075.1"
                     /db_xref="GI:6319995"
                     /db_xref="SGD:S000002365"
                     /db_xref="GeneID:851321"
                     /translation="MHKPLRWLITIAFYVSNVILIGYSLSSNGSISEFYLHSVVLIEC
                     FSLLGVVTSDCLTPSLSYISSNIFHISDRVSGMTLLALGNALPDITSTYQSMKSGVTS
                     LAIGELFGGIFFLLTVVIGLMGCVATIQFQHDKSIETYTEESFDQNLSYDRSNYILDV
                     GIFTFMLLVSGTFLADGRLYFWECIVMVLTYCCCAVYLIKSYKYPCEINDALEREVEI
                     KKTVLANNHITVPNRFTLTTTSDITSTDDGIRYVRPLGDTQIDEDNAISLDPTRLPSK
                     SLDNISRFNQGIPERRDLIRRRIRGYLRSHYHGWVRMTLQDLLNIWEKQNLFNNTVKS
                     LSLPSDDTHLFTKASLDEEGRPLIRKRMNSLQPKDFYKYLSLRNGENSNALDTAISAP
                     QNEYQTYYNEPTSLFLTVPQKKTSKKSLSCDRIPNLVRSNNIILNDEATRTQESTNAL
                     NSISDVIDNSLLQYERDDIILDRTLSLCSTKSRTAWHSFQLYNYLTDVSLEIGFFEFL
                     SLLVTTPVSIILYLSIPSEISQTDHDLPLSYLQNIQLIASPIILNQLITNNFSFWLLI
                     LSLVIAILLYFKTRTIPNKFNSDIIFTVAFLLSLACLSKAVHIIVVTLTHWINVFNIS
                     ETILGLTIFTWGNSIGDLVSNITFVKIGVLEIAIGACFGSPLLYFLFGVGFDGIMIML
                     GDKTGKIVSGRDSNILMHHIDFKVDKNLINTGVGILIAFLIFTVLIPLNDWKIDKKIS
                     IALLTLYIVVTCISVFLEVHQV"
     gene            complement(<92762..>93745)
                     /gene="HEM3"
                     /locus_tag="YDL205C"
                     /gene_synonym="OLE2"
                     /db_xref="GeneID:851322"
     mRNA            complement(<92762..>93745)
                     /gene="HEM3"
                     /locus_tag="YDL205C"
                     /gene_synonym="OLE2"
                     /product="hydroxymethylbilane synthase"
                     /transcript_id="NM_001180265.1"
                     /db_xref="GI:296143167"
                     /db_xref="GeneID:851322"
     CDS             complement(92762..93745)
                     /gene="HEM3"
                     /locus_tag="YDL205C"
                     /gene_synonym="OLE2"
                     /EC_number="2.5.1.61"
                     /note="Porphobilinogen deaminase; catalyzes the conversion
                     of 4-porphobilinogen to hydroxymethylbilane, the third
                     step in heme biosynthesis; localizes to the cytoplasm and
                     nucleus; expression is regulated by Hap2p-Hap3p, but not
                     by levels of heme"
                     /codon_start=1
                     /product="hydroxymethylbilane synthase"
                     /protein_id="NP_010076.1"
                     /db_xref="GI:6319996"
                     /db_xref="SGD:S000002364"
                     /db_xref="GeneID:851322"
                     /translation="MGPETLHIGGRKSKLAVIQSNHVLKLIEEKYPDYDCKVFTLQTL
                     GDQIQFKPLYSFGGKALWTKELEDHLYHDDPSKKLDLIVHSLKDMPTLLPEGFELGGI
                     TKRVDPTDCLVMPFYSAYKSLDDLPDGGIVGTSSVRRSAQLKRKYPHLKFESVRGNIQ
                     TRLQKLDDPKSPYQCIILASAGLMRMGLENRITQRFHSDTMYHAVGQGALGIEIRKGD
                     TKMMKILDEICDLNATICCLSERALMRTLEGGCSVPIGVESKYNEETKKLLLKAIVVD
                     VEGTEAVEDEIEMLIENVKEDSMACGKILAERMIADGAKKILDEINLDRIK"
     gene            <94605..>95786
                     /gene="RTN2"
                     /locus_tag="YDL204W"
                     /db_xref="GeneID:851323"
     mRNA            <94605..>95786
                     /gene="RTN2"
                     /locus_tag="YDL204W"
                     /product="Rtn2p"
                     /transcript_id="NM_001180264.1"
                     /db_xref="GI:296143168"
                     /db_xref="GeneID:851323"
     CDS             94605..95786
                     /gene="RTN2"
                     /locus_tag="YDL204W"
                     /note="Reticulon protein; stabilizes membrane curvature;
                     involved in nuclear pore assembly and maintenance of
                     tubular ER morphology; interacts with exocyst subunit
                     Sec6p, Yip3p, and Sbh1p; much less abundant than Rtn1p;
                     rtn1 rtn2 yop1 triple mutant lacks tubular ER; member of
                     RTNLA (reticulon-like A) subfamily; protein increases in
                     abundance and relocalizes to plasma membrane upon DNA
                     replication stress; RTN2 has a paralog, RTN1, that arose
                     from the whole genome duplication"
                     /codon_start=1
                     /product="Rtn2p"
                     /protein_id="NP_010077.1"
                     /db_xref="GI:6319997"
                     /db_xref="SGD:S000002363"
                     /db_xref="GeneID:851323"
                     /translation="MNRNTTTNKNANLNNSRNANAPGEAGHQNKTGLIYWTNPSKSGA
                     SFAATLVSLLILRNVNVISVLLKIGYMVLFTSFAVELSTKVLFDKGVVSRFGMQESPD
                     LVGVLKPHIDRELDRLPALEDRIRKLVFAHRTRNNFTIGVSLYFLHGLFAIFSMNTVL
                     IMTTIFLYTVPLIYDRKQARIDRAIDRMKDLVIHRFHKNYNKVVEKTEPYIDKIIPPQ
                     TDEGSYSTSISNENKSSTSQRNKSGLSSSEFDNMNDTSASKSGKDSYSTSQYNRAEYP
                     VSQNENIGTLKSGKQEIPTEKDFNNRHENFSKPDVKTYDPRTVDIEEELAAHQRELEQ
                     NLKDGDYNLVGSKEIPDPITVPAPTRHTTKPAESQSIPIKNNETLHKTTHGLKQKLQH
                     A"
     gene            complement(<96082..>97953)
                     /gene="ACK1"
                     /locus_tag="YDL203C"
                     /db_xref="GeneID:851324"
     mRNA            complement(<96082..>97953)
                     /gene="ACK1"
                     /locus_tag="YDL203C"
                     /product="Ack1p"
                     /transcript_id="NM_001180263.1"
                     /db_xref="GI:296143169"
                     /db_xref="GeneID:851324"
     CDS             complement(96082..97953)
                     /gene="ACK1"
                     /locus_tag="YDL203C"
                     /note="Protein that functions in the cell wall integrity
                     pathway; functions upstream of Pkc1p; GFP-fusion protein
                     expression is induced in response to the DNA-damaging
                     agent MMS; non-tagged Ack1p is detected in purified
                     mitochondria"
                     /codon_start=1
                     /product="Ack1p"
                     /protein_id="NP_010078.1"
                     /db_xref="GI:6319998"
                     /db_xref="SGD:S000002362"
                     /db_xref="GeneID:851324"
                     /translation="MVNQGQPQPNLYDKHINMFPPARARESSHKLGNANSDRHGLPAQ
                     NIVPAPYPVDDSIVELTPAIPFTSPSSSSSLSLPLSALNFTDGNADGGQLGTPVTINS
                     NNGMDIFNSKPTGEIGYANNGTNSTGSRYELPFNFSSTKESLGSPAVQDASISSGNRI
                     SESVRDNSAPPPYEESESRILQEKVYRTEEKAPIRPLNNNPVPPQKINQPPTGSAKTD
                     DNGSSGGEDKLSSYSPEALAFYQVYKKTITDSSKFTPEIQMQWCETLLTYAFNEDFIS
                     QYNINAEKLKRSLKPEEMLKNQKVILEHSFKVLTKLITLKWPPAMYLMGTLYSHQPYL
                     PIKNKNIVIKNDEKALEYYCKAAKLNNSDACYRAGVCFEYQRGTSSLDPSPTKEQCIK
                     KAFQYYQHGAEVCSNSACMYKLGMSHLYGLNMQKTDVLLAIKWFDKAAQKGDSPQTLY
                     ELGKIYEFSVLPPEIQNLLFANGIRKDSQLAIKYYQQCAKDFEYPLAQWKLGNCYEFG
                     DLGLPVVAKKSIYWYSKAAAAQPKGNPMAMLSLSGWYLTGAPNILKPNNKEAFNWALK
                     SSKCSDGKLARTEFALGFYYEKGVGCEVDLDLAKQYYQRAARMGFRKAVDALRSLTN"
     gene            <98475..>99224
                     /gene="MRPL11"
                     /locus_tag="YDL202W"
                     /db_xref="GeneID:851325"
     mRNA            <98475..>99224
                     /gene="MRPL11"
                     /locus_tag="YDL202W"
                     /product="mitochondrial 54S ribosomal protein YmL11"
                     /transcript_id="NM_001180262.1"
                     /db_xref="GI:296143170"
                     /db_xref="GeneID:851325"
     CDS             98475..99224
                     /gene="MRPL11"
                     /locus_tag="YDL202W"
                     /note="Mitochondrial ribosomal protein of the large
                     subunit; localizes to vacuole in response to H2O2"
                     /codon_start=1
                     /product="mitochondrial 54S ribosomal protein YmL11"
                     /protein_id="NP_010079.1"
                     /db_xref="GI:6319999"
                     /db_xref="SGD:S000002361"
                     /db_xref="GeneID:851325"
                     /translation="MLQLRFMPGWVPRNGFFGLKETIGTVHKRFYALASEQPSRKTVK
                     PLDSRKTFLIDTYKHLMENSSMIFFVHYNNLSKTEDHHFRFKIKQTGGKLTKVRNNLF
                     EVYLRNSHLPDPCGFVKRKEQNWKHPLLPLLKGPTATITYEDTNPQQVAKLLKVLQSA
                     QDKLMVIGAKVENEVLNVEKINTFKTLPTKPEMQSQLVSVLQMLSGLGLVRTLENSSN
                     ALYLTLKSHNDNQKPKEDVESTTDAESKGSK"
     gene            <99561..>100421
                     /gene="TRM8"
                     /locus_tag="YDL201W"
                     /db_xref="GeneID:851326"
     mRNA            <99561..>100421
                     /gene="TRM8"
                     /locus_tag="YDL201W"
                     /product="Trm8p"
                     /transcript_id="NM_001180261.1"
                     /db_xref="GI:296143171"
                     /db_xref="GeneID:851326"
     CDS             99561..100421
                     /gene="TRM8"
                     /locus_tag="YDL201W"
                     /EC_number="2.1.1.33"
                     /note="Noncatalytic subunit of a tRNA methyltransferase
                     complex; Trm8p and Trm82p comprise an enzyme that
                     catalyzes a methyl-transfer from S-adenosyl-l-methionine
                     to the N(7) atom of guanine at position 46 in tRNA; Trm8
                     lacks catalytic activity if not bound to Trm82p"
                     /codon_start=1
                     /product="Trm8p"
                     /protein_id="NP_010080.1"
                     /db_xref="GI:6320000"
                     /db_xref="SGD:S000002360"
                     /db_xref="GeneID:851326"
                     /translation="MKAKPLSQDPGSKRYAYRINKEENRKELKHVKINESSLVQEGQK
                     IDLPKKRYYRQRAHSNPFSDHQLEYPVSPQDMDWSKLYPYYKNAENGQMTKKVTIADI
                     GCGFGGLMIDLSPAFPEDLILGMEIRVQVTNYVEDRIIALRNNTASKHGFQNINVLRG
                     NAMKFLPNFFEKGQLSKMFFCFPDPHFKQRKHKARIITNTLLSEYAYVLKEGGVVYTI
                     TDVKDLHEWMVKHLEEHPLFERLSKEWEENDECVKIMRNATEEGKKVERKKGDKFVAC
                     FTRLPTPAIL"
     gene            complement(<100501..>101067)
                     /gene="MGT1"
                     /locus_tag="YDL200C"
                     /db_xref="GeneID:851327"
     mRNA            complement(<100501..>101067)
                     /gene="MGT1"
                     /locus_tag="YDL200C"
                     /product="Mgt1p"
                     /transcript_id="NM_001180260.1"
                     /db_xref="GI:296143172"
                     /db_xref="GeneID:851327"
     CDS             complement(100501..101067)
                     /gene="MGT1"
                     /locus_tag="YDL200C"
                     /EC_number="2.1.1.63"
                     /note="DNA repair methyltransferase (6-O-methylguanine-DNA
                     methylase); involved in protection against DNA alkylation
                     damage"
                     /codon_start=1
                     /product="Mgt1p"
                     /protein_id="NP_010081.2"
                     /db_xref="GI:93117370"
                     /db_xref="SGD:S000002359"
                     /db_xref="GeneID:851327"
                     /translation="MKELLYYTFIETEVTGAFLVFREKTQNLVFASLGNDKLFLLGKV
                     EGFLKKHEKQDTMYDLQELKEAETYKKSIENYTICLENKMPLPSGAIPFEFLFGTDFQ
                     RKVWNELLNVEHGHVVTYGDIAKRIGKPTAARSVGRACGSNNLALLVPCHRIVGSNRK
                     LTGYKWSCKLKEQLLNNEKENSLSLSRL"
     gene            complement(<101290..>103353)
                     /locus_tag="YDL199C"
                     /db_xref="GeneID:851328"
     mRNA            complement(<101290..>103353)
                     /locus_tag="YDL199C"
                     /product="hypothetical protein"
                     /transcript_id="NM_001180259.1"
                     /db_xref="GI:296143173"
                     /db_xref="GeneID:851328"
     CDS             complement(101290..103353)
                     /locus_tag="YDL199C"
                     /note="Putative transporter; member of the sugar porter
                     family"
                     /codon_start=1
                     /product="hypothetical protein"
                     /protein_id="NP_010082.1"
                     /db_xref="GI:6320002"
                     /db_xref="SGD:S000002358"
                     /db_xref="GeneID:851328"
                     /translation="MKPPLNMSRSNKPLTQEANSSAHIDRAHQLAQDFNSKQDDTALT
                     SLPHKNPDIFRFENNITAHSSRRGSLYRDSDATVVLPLSEHTPRLSMDDPYRQLLQQA
                     EISQLRSKKKRHSSRVLRTSFISFVVLVSSLSGLDQGLISGNVMTLSFQKYFHYPLTS
                     PLGNIVSIVNLGAFMASLFVYSGILEPCSRKKMLQISTMIYSLGAIVQVLALNQWCLL
                     LGRFLLGVGMGFAFSMVIIYQFEFPLPCIRKRTLISIQCVSSVIAYSFGIWINCAFRY
                     LGFAWRYPLSTHVALGIILNLMSFYLILESPSWLLKQKNDVEALVLISNVFDDGNFEE
                     NQTQLKFRVLKRDILLKSHLQKNSYPYAYILKDFSSIIKLLIGFQLLTRTNGVDAFLY
                     YSPLILQQMGRGERKSIYLTGLNALIYSIVILAYVPLVLRKRKEKTNVLLGSIVMCAL
                     LFTISFTDWFPKSTTRYISILFAVFLFTHFISWDSIGWVMTIELLPHLSQAPVILLVS
                     NFYWIFKWFVSLITPILIDRLSWKFYLIPSLSSFISIIFVLKIFPIETRDERLDSDDD
                     STGNGSGNHDDVFDDTGSEFSSSPSFSAYQINTLGSSIKQNNQAYSSIQNEQILPKNG
                     NLSNQTHGSAQNVYFITSDSGPSRTGEFFSFHNRTDPNISDNIAANKPSSGGGQNSPG
                     DMAVA"
     gene            complement(<103649..>104551)
                     /gene="GGC1"
                     /locus_tag="YDL198C"
                     /gene_synonym="SHM1; YHM1"
                     /db_xref="GeneID:851329"
     mRNA            complement(<103649..>104551)
                     /gene="GGC1"
                     /locus_tag="YDL198C"
                     /gene_synonym="SHM1; YHM1"
                     /product="Ggc1p"
                     /transcript_id="NM_001180258.1"
                     /db_xref="GI:296143174"
                     /db_xref="GeneID:851329"
     CDS             complement(103649..104551)
                     /gene="GGC1"
                     /locus_tag="YDL198C"
                     /gene_synonym="SHM1; YHM1"
                     /note="Mitochondrial GTP/GDP transporter; essential for
                     mitochondrial genome maintenance; has a role in
                     mitochondrial iron transport; member of the mitochondrial
                     carrier family"
                     /codon_start=1
                     /product="Ggc1p"
                     /protein_id="NP_010083.1"
                     /db_xref="GI:6320003"
                     /db_xref="SGD:S000002357"
                     /db_xref="GeneID:851329"
                     /translation="MPHTDKKQSGLARLLGSASAGIMEIAVFHPVDTISKRLMSNHTK
                     ITSGQELNRVIFRDHFSEPLGKRLFTLFPGLGYAASYKVLQRVYKYGGQPFANEFLNK
                     HYKKDFDNLFGEKTGKAMRSAAAGSLIGIGEIVLLPLDVLKIKRQTNPESFKGRGFIK
                     ILRDEGLFNLYRGWGWTAARNAPGSFALFGGNAFAKEYILGLKDYSQATWSQNFISSI
                     VGACSSLIVSAPLDVIKTRIQNRNFDNPESGLRIVKNTLKNEGVTAFFKGLTPKLLTT
                     GPKLVFSFALAQSLIPRFDNLLSK"
     gene            complement(<104917..>106494)
                     /gene="ASF2"
                     /locus_tag="YDL197C"
                     /db_xref="GeneID:851330"
     mRNA            complement(<104917..>106494)
                     /gene="ASF2"
                     /locus_tag="YDL197C"
                     /product="Asf2p"
                     /transcript_id="NM_001180257.1"
                     /db_xref="GI:296143175"
                     /db_xref="GeneID:851330"
     CDS             complement(104917..106494)
                     /gene="ASF2"
                     /locus_tag="YDL197C"
                     /note="Anti-silencing protein; causes derepression of
                     silent loci when overexpressed"
                     /codon_start=1
                     /product="Asf2p"
                     /protein_id="NP_010084.1"
                     /db_xref="GI:6320004"
                     /db_xref="SGD:S000002356"
                     /db_xref="GeneID:851330"
                     /translation="MPKNRGVLDAITRSVIDGSDQESSSSFNSDKEYAAVTKGLSSSR
                     VQKKSSLRQMKSKVKELQSLVNHYRENEAALVSSAKLLSGEIIGYEIKMASLHGKMKS
                     ILDENNALKETHKSSAEKRIELVRLPSSKEERNYDEYTLLVNLKKEICAKLQDYKNVQ
                     NTVNTKLDEIHTFHEKYYEGLELSLDSKVFDAESSKELAKVRRELNNVRKNSEIKVNN
                     LKMQLLQATKSLEHLKKQAKAKDDYLKCIPELVDKANLTMLSYKKSIANQRETIEALQ
                     AELSQQSETKGQIETETQNQVQIPTNVTLVDPFEENNPEDLFAIQEQELQDLRLHKKM
                     ADERSRTTHLHLERKNNTIKLLQSYVQSLIQRLPPAQRKHHLGIFQKLGSEKSCPLAP
                     AVASTYAPLLLLSQHSNHQEIDNTPQRLLLAAPDGQSYSEKSTTLNLDYSSRKSYLSR
                     LQPPHIANLKSLTLKTLPRVPTDSPQLPSKDKSQETAKKDDRPKLVANEPVTLDTSTP
                     PVAQSLADSKHCSGLHK"
     gene            <107208..>111029
                     /gene="SEC31"
                     /locus_tag="YDL195W"
                     /gene_synonym="WEB1"
                     /db_xref="GeneID:851332"
     mRNA            <107208..>111029
                     /gene="SEC31"
                     /locus_tag="YDL195W"
                     /gene_synonym="WEB1"
                     /product="Sec31p"
                     /transcript_id="NM_001180255.2"
                     /db_xref="GI:330443496"
                     /db_xref="GeneID:851332"
     CDS             107208..111029
                     /gene="SEC31"
                     /locus_tag="YDL195W"
                     /gene_synonym="WEB1"
                     /note="Component of the Sec13p-Sec31p complex of the COPII
                     vesicle coat; COPII coat is required for vesicle formation
                     in ER to Golgi transport; mutant has increased aneuploidy
                     tolerance"
                     /codon_start=1
                     /product="Sec31p"
                     /protein_id="NP_010086.2"
                     /db_xref="GI:330443497"
                     /db_xref="SGD:S000002354"
                     /db_xref="GeneID:851332"
                     /translation="MVKLAEFSRTATFAWSHDKIPLLVSGTVSGTVDANFSTDSSLEL
                     WSLLAADSEKPIASLQVDSKFNDLDWSHNNKIIAGALDNGSLELYSTNEANNAINSMA
                     RFSNHSSSVKTVKFNAKQDNVLASGGNNGEIFIWDMNKCTESPSNYTPLTPGQSMSSV
                     DEVISLAWNQSLAHVFASAGSSNFASIWDLKAKKEVIHLSYTSPNSGIKQQLSVVEWH
                     PKNSTRVATATGSDNDPSILIWDLRNANTPLQTLNQGHQKGILSLDWCHQDEHLLLSS
                     GRDNTVLLWNPESAEQLSQFPARGNWCFKTKFAPEAPDLFACASFDNKIEVQTLQNLT
                     NTLDEQETETKQQESETDFWNNVSREESKEKPTVFHLQAPTWYGEPSPAAHWAFGGKL
                     VQITPDGKGVSITNPKISGLESNTTLSEALKTKDFKPLINQRLVKVIDDVNEEDWNLL
                     EKLSMDGTEEFLKEALAFDNDESDAQDDANNEKEDDGEEFFQQIETNFQPEGDFSLSG
                     NIEQTISKNLVSGNIKSAVKNSLENDLLMEAMVIALDSNNERLKESVKNAYFAKYGSK
                     SSLSRILYSISKREVDDLVENLDVSQWKFISKAIQNLYPNDIAQRNEMLIKLGDRLKE
                     NGHRQDSLTLYLAAGSLDKVASIWLSEFPDLEDKLKKDNKTIYEAHSECLTEFIERFT
                     VFSNFINGSSTINNEQLIAKFLEFINLTTSTGNFELATEFLNSLPSDNEEVKTEKARV
                     LIASGKSLPAQNPATATTSKAKYTNAKTNKNVPVLPTPGMPSTTSIPSMQAPFYGMTP
                     GASANALPPKPYVPATTTSAPVHTEGKYAPPSQPSMASPFVNKTNSSTRLNSFAPPPN
                     PYATATVPATNVSTTSIPQNTFAPIQPGMPIMGDYNAQSSSIPSQPPINAVSGQTPHL
                     NRKANDGWNDLPLKVKEKPSRAKAVSVAPPNILSTPTPLNGIPANAASTMPPPPLSRA
                     PSSVSMVSPPPLHKNSRVPSLVATSESPRASISNPYAPPQSSQQFPIGTISTANQTSN
                     TAQVASSNPYAPPPQQRVATPLSGGVPPAPLPKASNPYAPTATTQPNGSSYPPTGPYT
                     NNHTMTSPPPVFNKPPTGPPPISMKKRSNKLASIEQNPSQGATYPPTLSSSASPLQPS
                     QPPTLASQVNTSAENVSHEIPADQQPIVDFLKEELARVTPLTPKEYSKQLKDCDKRLK
                     ILFYHLEKQDLLTQPTIDCLHDLVALMKEKKYKEAMVIHANIATNHAQEGGNWLTGVK
                     RLIGIAEATLN"
     gene            <111580..>114234
                     /gene="SNF3"
                     /locus_tag="YDL194W"
                     /db_xref="GeneID:851333"
     mRNA            <111580..>114234
                     /gene="SNF3"
                     /locus_tag="YDL194W"
                     /product="Snf3p"
                     /transcript_id="NM_001180254.1"
                     /db_xref="GI:296143177"
                     /db_xref="GeneID:851333"
     CDS             111580..114234
                     /gene="SNF3"
                     /locus_tag="YDL194W"
                     /note="Plasma membrane low glucose sensor, regulates
                     glucose transport; contains 12 predicted transmembrane
                     segments and a long C-terminal tail required for induction
                     of hexose transporters; also senses fructose and mannose;
                     SNF3 has a paralog, RGT2, that arose from the whole genome
                     duplication"
                     /codon_start=1
                     /product="Snf3p"
                     /protein_id="NP_010087.1"
                     /db_xref="GI:6320007"
                     /db_xref="SGD:S000002353"
                     /db_xref="GeneID:851333"
                     /translation="MDPNSNSSSETLRQEKQGFLDKALQRVKGIALRRNNSNKDHTTD
                     DTTGSIRTPTSLQRQNSDRQSNMTSVFTDDISTIDDNSILFSEPPQKQSMMMSICVGV
                     FVAVGGFLFGYDTGLINSITSMNYVKSHVAPNHDSFTAQQMSILVSFLSLGTFFGALT
                     APFISDSYGRKPTIIFSTIFIFSIGNSLQVGAGGITLLIVGRVISGIGIGAISAVVPL
                     YQAEATHKSLRGAIISTYQWAITWGLLVSSAVSQGTHARNDASSYRIPIGLQYVWSSF
                     LAIGMFFLPESPRYYVLKDKLDEAAKSLSFLRGVPVHDSGLLEELVEIKATYDYEASF
                     GSSNFIDCFISSKSRPKQTLRMFTGIALQAFQQFSGINFIFYYGVNFFNKTGVSNSYL
                     VSFITYAVNVVFNVPGLFFVEFFGRRKVLVVGGVIMTIANFIVAIVGCSLKTVAAAKV
                     MIAFICLFIAAFSATWGGVVWVISAELYPLGVRSKCTAICAAANWLVNFICALITPYI
                     VDTGSHTSSLGAKIFFIWGSLNAMGVIVVYLTVYETKGLTLEEIDELYIKSSTGVVSP
                     KFNKDIRERALKFQYDPLQRLEDGKNTFVAKRNNFDDETPRNDFRNTISGEIDHSPNQ
                     KEVHSIPERVDIPTSTEILESPNKSSGMTVPVSPSLQDVPIPQTTEPAEIRTKYVDLG
                     NGLGLNTYNRGPPSLSSDSSEDYTEDEIGGPSSQGDQSNRSTMNDINDYMARLIHSTS
                     TASNTTDKFSGNQSTLRYHTASSHSDTTEEDSNLMDLGNGLALNAYNRGPPSILMNSS
                     DEEANGGETSDNLNTAQDLAGMKERMAQFAQSYIDKRGGLEPETQSNILSTSLSVMAD
                     TNEHNNEILHSSEENATNQPVNENNDLK"
     gene            <114672..>115799
                     /gene="NUS1"
                     /locus_tag="YDL193W"
                     /db_xref="GeneID:851334"
     mRNA            <114672..>115799
                     /gene="NUS1"
                     /locus_tag="YDL193W"
                     /product="Nus1p"
                     /transcript_id="NM_001180253.1"
                     /db_xref="GI:296143178"
                     /db_xref="GeneID:851334"
     CDS             114672..115799
                     /gene="NUS1"
                     /locus_tag="YDL193W"
                     /EC_number="2.5.1.31"
                     /note="Putative prenyltransferase; required for cell
                     viability; proposed to be involved in protein trafficking
                     because tet-repressible mutant shows accumulation of
                     hypoglycosylated forms of CPY"
                     /codon_start=1
                     /product="Nus1p"
                     /protein_id="NP_010088.1"
                     /db_xref="GI:6320008"
                     /db_xref="SGD:S000002352"
                     /db_xref="GeneID:851334"
                     /translation="MPTMIKKDDKAMEPPNEKPHRKIERDDVPESSNHIPPPESGVLK
                     GGKVNSKTRALKAVTSIIADADENPQKKVNNETNGVQKQKTEDLSKRIGKFEYLFYKF
                     LLVLLYICFGLFRYGQYQYNKMKLRIFSIIYNHAYTPQLIRQDVIPLKKIPKRLAAIL
                     EVKPVGDVGGGVTGLLNDASEIVCWTVSAGIKHLMLYDYDGILQRNVPELRMEIHSNL
                     AKYFGPAHVPNYAVKIPHSNKIFYNLDGIETETDVGNEIEANQEKDKIAIEISLLSNR
                     DGRETIVDLTKTMAELCAVNELSVSDITMDLVDSELKQLVGPEPDLLLYFGPSLDLQG
                     FPPWHIRLTEFYWEKDNNEVIYSVFIRGLRQYAGCKVNVGK"
     gene            <116321..>116866
                     /gene="ARF1"
                     /locus_tag="YDL192W"
                     /db_xref="GeneID:851335"
     mRNA            <116321..>116866
                     /gene="ARF1"
                     /locus_tag="YDL192W"
                     /product="Arf family GTPase ARF1"
                     /transcript_id="NM_001180252.1"
                     /db_xref="GI:296143179"
                     /db_xref="GeneID:851335"
     CDS             116321..116866
                     /gene="ARF1"
                     /locus_tag="YDL192W"
                     /note="ADP-ribosylation factor; GTPase of the Ras
                     superfamily involved in regulation of coated vesicle
                     formation in intracellular trafficking within the Golgi;
                     ARF1 has a paralog, ARF2, that arose from the whole genome
                     duplication"
                     /codon_start=1
                     /product="Arf family GTPase ARF1"
                     /protein_id="NP_010089.1"
                     /db_xref="GI:6320009"
                     /db_xref="SGD:S000002351"
                     /db_xref="GeneID:851335"
                     /translation="MGLFASKLFSNLFGNKEMRILMVGLDGAGKTTVLYKLKLGEVIT
                     TIPTIGFNVETVQYKNISFTVWDVGGQDRIRSLWRHYYRNTEGVIFVVDSNDRSRIGE
                     AREVMQRMLNEDELRNAAWLVFANKQDLPEAMSAAEITEKLGLHSIRNRPWFIQATCA
                     TSGEGLYEGLEWLSNSLKNST"
     gene            <117664..>118517
                     /gene="RPL35A"
                     /locus_tag="YDL191W"
                     /gene_synonym="SOS1"
                     /db_xref="GeneID:851336"
     mRNA            join(<117664..117666,118158..>118517)
                     /gene="RPL35A"
                     /locus_tag="YDL191W"
                     /gene_synonym="SOS1"
                     /product="ribosomal 60S subunit protein L35A"
                     /transcript_id="NM_001180196.2"
                     /db_xref="GI:330443498"
                     /db_xref="GeneID:851336"
     CDS             join(117664..117666,118158..118517)
                     /gene="RPL35A"
                     /locus_tag="YDL191W"
                     /gene_synonym="SOS1"
                     /note="Ribosomal 60S subunit protein L35A; homologous to
                     mammalian ribosomal protein L35 and bacterial L29; RPL35A
                     has a paralog, RPL35B, that arose from the whole genome
                     duplication"
                     /codon_start=1
                     /product="ribosomal 60S subunit protein L35A"
                     /protein_id="NP_010145.1"
                     /db_xref="GI:6320065"
                     /db_xref="SGD:S000002350"
                     /db_xref="GeneID:851336"
                     /translation="MAGVKAYELRTKSKEQLASQLVDLKKELAELKVQKLSRPSLPKI
                     KTVRKSIACVLTVINEQQREAVRQLYKGKKYQPKDLRAKKTRALRRALTKFEASQVTE
                     KQRKKQIAFPQRKYAIKA"
     gene            complement(<118707..>121592)
                     /gene="UFD2"
                     /locus_tag="YDL190C"
                     /db_xref="GeneID:851337"
     mRNA            complement(<118707..>121592)
                     /gene="UFD2"
                     /locus_tag="YDL190C"
                     /product="ubiquitin-ubiquitin ligase UFD2"
                     /transcript_id="NM_001180250.2"
                     /db_xref="GI:330443499"
                     /db_xref="GeneID:851337"
     CDS             complement(118707..121592)
                     /gene="UFD2"
                     /locus_tag="YDL190C"
                     /EC_number="6.3.2.-"
                     /note="Ubiquitin chain assembly factor (E4); cooperates
                     with a ubiquitin-activating enzyme (E1), a
                     ubiquitin-conjugating enzyme (E2), and a ubiquitin protein
                     ligase (E3) to conjugate ubiquitin to substrates; also
                     functions as an E3"
                     /codon_start=1
                     /product="ubiquitin-ubiquitin ligase UFD2"
                     /protein_id="NP_010091.2"
                     /db_xref="GI:330443500"
                     /db_xref="SGD:S000002349"
                     /db_xref="GeneID:851337"
                     /translation="MTAIEDILQITTDPSDTRGYSLLKSEEVPQGSTLGVDFIDTLLL
                     YQLTENEKLDKPFEYLNDCFRRNQQQKRITKNKPNAESLHSTFQEIDRLVIGYGVVAL
                     QIENFCMNGAFINYITGIVSNVNSYTDFLSQIIQRAILEGTALDLLNAVFPTLLEYCN
                     KHVSHFDLNESVIYNNVLTIFELFVTFKPIAEIFTKIDGFFADYSCKPQDFERKTILG
                     PILSLSPIEAAVAIRNYGDNLLRSKQQTAMIHESLQAEHKVVIDRLFFIVDKLVRGSL
                     NSRTDMISYFAHIANKNHLRRADHPPFKELSSNGFMSNITLLLVRFSQPFLDISYKKI
                     DKIDANYFNNPSLFIDLSGETRLNSDFKEADAFYDKNRKTADSKPNFISDCFFLTLTY
                     LHYGLGGTLSFEEKMGSEIKALKEEIEKVKKIAANHDVFARFITAQLSKMEKALKTTE
                     SLRFALQGFFAHRSLQLEVFDFICGASTFLIRVVDPEHEFPFKQIKLPLIPDQIGVEN
                     VDNADFLRAHAPVPFKYYPEFVVEGPVNYSLYISKYQTSPIFRNPRLGSFVEFTTMVL
                     RCPELVSNPHLKGKLVQLLSVGAMPLTDNSPGFMMDIFEHDELVNKNLLYALLDFYVI
                     VEKTGSSSQFYDKFNSRYSISIILEELYYKIPSYKNQLIWQSQNNADFFVRFVARMLN
                     DLTFLLDEGLSNLAEVHNIQNELDNRARGAPPTREEEDKELQTRLASASRQAKSSCGL
                     ADKSMKLFEIYSKDIPAAFVTPEIVYRLASMLNYNLESLVGPKCGELKVKDPQSYSFN
                     PKDLLKALTTVYINLSEQSEFISAVAKDERSFNRNLFVRAVDILGRKTGLASPEFIEK
                     LLNFANKAEEQRKADEEEDLEYGDVPDEFLDPLMYTIMKDPVILPASKMNIDRSTIKA
                     HLLSDSTDPFNRMPLKLEDVTPNEELRQKILCFKKQKKEEAKHKASE"
     gene            <122216..>123589
                     /gene="RBS1"
                     /locus_tag="YDL189W"
                     /db_xref="GeneID:851338"
     mRNA            <122216..>123589
                     /gene="RBS1"
                     /locus_tag="YDL189W"
                     /product="Rbs1p"
                     /transcript_id="NM_001180249.1"
                     /db_xref="GI:296143182"
                     /db_xref="GeneID:851338"
     CDS             122216..123589
                     /gene="RBS1"
                     /locus_tag="YDL189W"
                     /note="hypothetical protein; identified as a high copy
                     suppressor of psk1 psk2 mutations that confer
                     temperature-sensitivity for galactose utilization;
                     proposed to bind single-stranded nucleic acids via its R3H
                     domain"
                     /codon_start=1
                     /product="Rbs1p"
                     /protein_id="NP_010092.2"
                     /db_xref="GI:9755328"
                     /db_xref="SGD:S000002348"
                     /db_xref="GeneID:851338"
                     /translation="MTALDSRNWGLTPAMETGLFQKPQDRIFIIELENSIVSFINSNT
                     ESFQLRPMNSYYRLLSHQIAEYHNLNHVLARTQDSCVILFKGENFQKIEGKPLLQELQ
                     LNKKPEECASSSESIEKSNNNRIFRILKRKEVGNECDYKIDGNTRTPNSNLTANSNKD
                     QKIEIDDKSSTDLEQERIEKERLYEQRKQEIFDKLNKSEDDVKSTNSSGSSDSDNEWS
                     DWLNGDDSNTQTSNGSVSSSSPFNSSVTTIQVNKPQQQFYDSRRGRGGRRRGTNNYKD
                     AYRGQSRRNKENGGYQSGYSSPYLVYPPPQMGGNSLPTYPLMYNPAGPAPGPAPSPMV
                     MGNNTVFMNPYMYNMNPQGSCSFGTPIPMYPPYQYQYQYQYNTQYHSGPYSNTPSYNS
                     NNYTRSSANKYHHFQGKNSYSGAIPKRSDDSNSNKNEGIRRASVEGSPSSRDTDSVEM
                     KFDKLNI"
     rep_origin      123617..123901
                     /note="ARS406;
                     Autonomously Replicating Sequence"
                     /db_xref="SGD:S000118429"
     gene            complement(<123865..>124998)
                     /gene="PPH22"
                     /locus_tag="YDL188C"
                     /gene_synonym="PPH2"
                     /db_xref="GeneID:851339"
     mRNA            complement(<123865..>124998)
                     /gene="PPH22"
                     /locus_tag="YDL188C"
                     /gene_synonym="PPH2"
                     /product="phosphoprotein phosphatase 2A catalytic subunit
                     PPH22"
                     /transcript_id="NM_001180248.1"
                     /db_xref="GI:296143183"
                     /db_xref="GeneID:851339"
     CDS             complement(123865..124998)
                     /gene="PPH22"
                     /locus_tag="YDL188C"
                     /gene_synonym="PPH2"
                     /EC_number="3.1.3.16"
                     /note="Catalytic subunit of protein phosphatase 2A (PP2A);
                     functionally redundant with Pph21p; methylated at C
                     terminus; forms alternate complexes with several
                     regulatory subunits; involved in signal transduction and
                     regulation of mitosis; protein abundance increases in
                     response to DNA replication stress; PPH22 has a paralog,
                     PPH21, that arose from the whole genome duplication"
                     /codon_start=1
                     /product="phosphoprotein phosphatase 2A catalytic subunit
                     PPH22"
                     /protein_id="NP_010093.1"
                     /db_xref="GI:6320013"
                     /db_xref="SGD:S000002347"
                     /db_xref="GeneID:851339"
                     /translation="MDMEIDDPMHGSDEDQLSPTLDEDMNSDDGKNNTKARSNDEDTD
                     EELEDFNFKPGSSGIADHKSSKPLKLTNTNINQLDQWIEHLSKCEPLSEDDVARLCKM
                     AVDVLQFEENVKPINVPVTICGDVHGQFHDLLELFKIGGPCPDTNYLFMGDYVDRGYY
                     SVETVSYLVAMKVRYPHRITILRGNHESRQITQVYGFYDECLRKYGSANVWKMFTDLF
                     DYFPVTALVDNKIFCLHGGLSPMIETIDQVRDLNRIQEVPHEGPMCDLLWSDPDDRGG
                     WGISPRGAGFTFGQDISEQFNHTNDLSLIARAHQLVMEGYSWSHQQNVVTIFSAPNYC
                     YRCGNQAAIMEVDENHNRQFLQYDPSVRPGEPTVTRKTPDYFL"
     gene            <125616..>126449
                     /locus_tag="YDL186W"
                     /db_xref="GeneID:851340"
     mRNA            <125616..>126449
                     /locus_tag="YDL186W"
                     /product="hypothetical protein"
                     /transcript_id="NM_001180246.1"
                     /db_xref="GI:296143184"
                     /db_xref="GeneID:851340"
     CDS             125616..126449
                     /locus_tag="YDL186W"
                     /note="hypothetical protein; YDL186W is not an essential
                     gene"
                     /codon_start=1
                     /product="hypothetical protein"
                     /protein_id="NP_010095.1"
                     /db_xref="GI:6320014"
                     /db_xref="SGD:S000002345"
                     /db_xref="GeneID:851340"
                     /translation="MQCNTSIEDGLDGGDITFPSYSPEAEAQNRFLPRSEFPSVRQLV
                     ISKQKSRRRREENVFVGKMEDVLVKWRPPASSHRGAIEAINGTHPYQLSTAQFNSRRS
                     DPFGSTKRDESVRSIVESFTDWWKRNSKMFFRDEEEGVRTEHSASQDDQELQLFEEDL
                     FSFHLSPNDMSTRNSEHQVQTPVLFPYEAPTRTKQNPAERKVIEIGDGEELSIYRDVY
                     SNPIPVSYLDTLNLNHSMSVRQTQQQQQQRQQQQYVDSSSAFQCCTDSNWARIFFCHH
                     D"
     gene            <126787..>130002
                     /gene="VMA1"
                     /locus_tag="YDL185W"
                     /gene_synonym="CLS8; TFP1"
                     /db_xref="GeneID:851342"
     mRNA            <126787..>130002
                     /gene="VMA1"
                     /locus_tag="YDL185W"
                     /gene_synonym="CLS8; TFP1"
                     /product="H(+)-transporting V1 sector ATPase subunit A"
                     /transcript_id="NM_001180245.1"
                     /db_xref="GI:296143185"
                     /db_xref="GeneID:851342"
     CDS             126787..130002
                     /gene="VMA1"
                     /locus_tag="YDL185W"
                     /gene_synonym="CLS8; TFP1"
                     /EC_number="3.6.3.14"
                     /EC_number="3.1.-.-"
                     /note="Subunit A of the V1 peripheral membrane domain of
                     V-ATPase; protein precursor undergoes self-catalyzed
                     splicing to yield the extein Tfp1p and the intein Vde
                     (PI-SceI), which is a site-specific endonuclease; the V1
                     peripheral membrane domain of the vacuolar H+-ATPase
                     (V-ATPase) has eight subunits; involved in methionine
                     restriction extension of chronological lifespan in an
                     autophagy-dependent manner"
                     /codon_start=1
                     /product="H(+)-transporting V1 sector ATPase subunit A"
                     /protein_id="NP_010096.1"
                     /db_xref="GI:6320016"
                     /db_xref="SGD:S000002344"
                     /db_xref="GeneID:851342"
                     /translation="MAGAIENARKEIKRISLEDHAESEYGAIYSVSGPVVIAENMIGC
                     AMYELVKVGHDNLVGEVIRIDGDKATIQVYEETAGLTVGDPVLRTGKPLSVELGPGLM
                     ETIYDGIQRPLKAIKEESQSIYIPRGIDTPALDRTIKWQFTPGKFQVGDHISGGDIYG
                     SVFENSLISSHKILLPPRSRGTITWIAPAGEYTLDEKILEVEFDGKKSDFTLYHTWPV
                     RVPRPVTEKLSADYPLLTGQRVLDALFPCVQGGTTCIPGAFGCGKTVISQSLSKYSNS
                     DAIIYVGCFAKGTNVLMADGSIECIENIEVGNKVMGKDGRPREVIKLPRGRETMYSVV
                     QKSQHRAHKSDSSREVPELLKFTCNATHELVVRTPRSVRRLSRTIKGVEYFEVITFEM
                     GQKKAPDGRIVELVKEVSKSYPISEGPERANELVESYRKASNKAYFEWTIEARDLSLL
                     GSHVRKATYQTYAPILYENDHFFDYMQKSKFHLTIEGPKVLAYLLGLWIGDGLSDRAT
                     FSVDSRDTSLMERVTEYAEKLNLCAEYKDRKEPQVAKTVNLYSKVVRGNGIRNNLNTE
                     NPLWDAIVGLGFLKDGVKNIPSFLSTDNIGTRETFLAGLIDSDGYVTDEHGIKATIKT
                     IHTSVRDGLVSLARSLGLVVSVNAEPAKVDMNGTKHKISYAIYMSGGDVLLNVLSKCA
                     GSKKFRPAPAAAFARECRGFYFELQELKEDDYYGITLSDDSDHQFLLANQVVVHNCGE
                     RGNEMAEVLMEFPELYTEMSGTKEPIMKRTTLVANTSNMPVAAREASIYTGITLAEYF
                     RDQGKNVSMIADSSSRWAEALREISGRLGEMPADQGFPAYLGAKLASFYERAGKAVAL
                     GSPDRTGSVSIVAAVSPAGGDFSDPVTTATLGITQVFWGLDKKLAQRKHFPSINTSVS
                     YSKYTNVLNKFYDSNYPEFPVLRDRMKEILSNAEELEQVVQLVGKSALSDSDKITLDV
                     ATLIKEDFLQQNGYSTYDAFCPIWKTFDMMRAFISYHDEAQKAVANGANWSKLADSTG
                     DVKHAVSSSKFFEPSRGEKEVHGEFEKLLSTMQERFAESTD"
     gene            complement(<130407..>130484)
                     /gene="RPL41A"
                     /locus_tag="YDL184C"
                     /gene_synonym="RPL47A"
                     /db_xref="GeneID:851344"
     mRNA            complement(<130407..>130484)
                     /gene="RPL41A"
                     /locus_tag="YDL184C"
                     /gene_synonym="RPL47A"
                     /product="ribosomal 60S subunit protein L41A"
                     /transcript_id="NM_001180244.1"
                     /db_xref="GI:296143186"
                     /db_xref="GeneID:851344"
     CDS             complement(130407..130484)
                     /gene="RPL41A"
                     /locus_tag="YDL184C"
                     /gene_synonym="RPL47A"
                     /note="Ribosomal 60S subunit protein L41A; comprises only
                     25 amino acids; rpl41a rpl41b double null mutant is
                     viable; homologous to mammalian ribosomal protein L41, no
                     bacterial homolog; RPL41A has a paralog, RPL41B, that
                     arose from the whole genome duplication"
                     /codon_start=1
                     /product="ribosomal 60S subunit protein L41A"
                     /protein_id="NP_010097.1"
                     /db_xref="GI:6320017"
                     /db_xref="SGD:S000002343"
                     /db_xref="GeneID:851344"
                     /translation="MRAKWRKKRTRRLKRKRRKVRARSK"
     gene            complement(<130871..>131833)
                     /locus_tag="YDL183C"
                     /db_xref="GeneID:851345"
     mRNA            complement(<130871..>131833)
                     /locus_tag="YDL183C"
                     /product="hypothetical protein"
                     /transcript_id="NM_001180243.1"
                     /db_xref="GI:296143187"
                     /db_xref="GeneID:851345"
     CDS             complement(130871..131833)
                     /locus_tag="YDL183C"
                     /note="Protein that may form an active mitochondrial KHE
                     system; mitochondrial inner-membrane protein;
                     non-essential gene; KHE system stands for K+/H+ exchanger
                     system"
                     /codon_start=1
                     /product="hypothetical protein"
                     /protein_id="NP_010098.1"
                     /db_xref="GI:6320018"
                     /db_xref="SGD:S000002342"
                     /db_xref="GeneID:851345"
                     /translation="MIRSIFIPPTSITATSRLFYGMRAYSTKLEKASLQKYLHDPVKV
                     TVIPITDKESFIYYKHTDNLFNSQSRILKAEKWIVEKSAKLWRKLKKSPKSYNKKIVS
                     MVQSLLNSTPWSENSLLTIPSESYILKRIKGEKDKTQEIRLTLKDYTVKAEQVDTQPL
                     HVYYPPGISSPDECLRQMKKLYQEGLIYHKKWTLYCLLGLPLTIPLILIPLIPNVPGF
                     YLSYRAYVNIKAYLGAKHLKSLLESSKQNLEFRELLGYTEVYKRGTSSRTQGNQKESK
                     GAPELLLNKKTLPLILDFLEVHELESDLNKVILQESKSQEKNKI"
     gene            <133437..>134723
                     /gene="LYS20"
                     /locus_tag="YDL182W"
                     /db_xref="GeneID:851346"
     mRNA            <133437..>134723
                     /gene="LYS20"
                     /locus_tag="YDL182W"
                     /product="homocitrate synthase LYS20"
                     /transcript_id="NM_001180242.1"
                     /db_xref="GI:296143188"
                     /db_xref="GeneID:851346"
     CDS             133437..134723
                     /gene="LYS20"
                     /locus_tag="YDL182W"
                     /EC_number="2.3.3.14"
                     /note="Homocitrate synthase isozyme; catalyzes the
                     condensation of acetyl-CoA and alpha-ketoglutarate to form
                     homocitrate, which is the first step in the lysine
                     biosynthesis pathway; LYS20 has a paralog, LYS21, that
                     arose from the whole genome duplication"
                     /codon_start=1
                     /product="homocitrate synthase LYS20"
                     /protein_id="NP_010099.1"
                     /db_xref="GI:6320019"
                     /db_xref="SGD:S000002341"
                     /db_xref="GeneID:851346"
                     /translation="MTAAKPNPYAAKPGDYLSNVNNFQLIDSTLREGEQFANAFFDTE
                     KKIEIARALDDFGVDYIELTSPVASEQSRKDCEAICKLGLKAKILTHIRCHMDDAKVA
                     VETGVDGVDVVIGTSKFLRQYSHGKDMNYIAKSAVEVIEFVKSKGIEIRFSSEDSFRS
                     DLVDLLNIYKTVDKIGVNRVGIADTVGCANPRQVYELIRTLKSVVSCDIECHFHNDTG
                     CAIANAYTALEGGARLIDVSVLGIGERNGITPLGGLMARMIVAAPDYVKSKYKLHKIR
                     DIENLVADAVEVNIPFNNPITGFCAFTHKAGIHAKAILANPSTYEILDPHDFGMKRYI
                     HFANRLTGWNAIKARVDQLNLNLTDDQIKEVTAKIKKLGDVRSLNIDDVDSIIKNFHA
                     EVSTPQVLSAKKNKKNDSDVPELATIPAAKRTKPSA"
     gene            <135179..>135436
                     /gene="INH1"
                     /locus_tag="YDL181W"
                     /db_xref="GeneID:851347"
     mRNA            <135179..>135436
                     /gene="INH1"
                     /locus_tag="YDL181W"
                     /product="Inh1p"
                     /transcript_id="NM_001180241.1"
                     /db_xref="GI:296143189"
                     /db_xref="GeneID:851347"
     CDS             135179..135436
                     /gene="INH1"
                     /locus_tag="YDL181W"
                     /note="Protein that inhibits ATP hydrolysis by the
                     F1F0-ATP synthase; inhibitory function is enhanced by
                     stabilizing proteins Stf1p and Stf2p; has a
                     calmodulin-binding motif and binds calmodulin in vitro;
                     INH1 has a paralog, STF1, that arose from the whole genome
                     duplication"
                     /codon_start=1
                     /product="Inh1p"
                     /protein_id="NP_010100.1"
                     /db_xref="GI:6320020"
                     /db_xref="SGD:S000002340"
                     /db_xref="GeneID:851347"
                     /translation="MLPRSALARSLQLQRGVAARFYSEGSTGTPRGSGSEDSFVKRER
                     ATEDFFVRQREKEQLRHLKEQLEKQRKKIDSLENKIDSMTK"
     gene            <135896..>137539
                     /locus_tag="YDL180W"
                     /db_xref="GeneID:851374"
     mRNA            <135896..>137539
                     /locus_tag="YDL180W"
                     /product="hypothetical protein"
                     /transcript_id="NM_001180240.1"
                     /db_xref="GI:296143190"
                     /db_xref="GeneID:851374"
     CDS             135896..137539
                     /locus_tag="YDL180W"
                     /note="hypothetical protein; green fluorescent protein
                     (GFP)-fusion protein localizes to the vacuole"
                     /codon_start=1
                     /product="hypothetical protein"
                     /protein_id="NP_010101.1"
                     /db_xref="GI:6320021"
                     /db_xref="SGD:S000002339"
                     /db_xref="GeneID:851374"
                     /translation="MVRLNHAASYFMPIFCSTRPHIVILSALFSISLFSLFYASSELL
                     LHQYDDPLMFKPNSQDYFRTFLLGLFSPFLYYFLKTFLFNINQRFLILNLIVDFPIND
                     VFMLLILIGLAYPQVQDHEGGTIKHKECSWHIIPRQAYIFGISWALGEFTICIIGNLF
                     NYQEIADPNINSGFTHQESANTYCNNNDMSHNDDCGCSTEYRPNVVDRSDITLSKCIE
                     VRNDSSSISNNVYSSEYHPIKPLRSSSSTYGSIRQQPHENKKQLHVPDNSQDDTIIMM
                     NPIDNSLKLTTLDTGDLSFPIDEEQPILKKSFGYTWAVPNENTQNTTKSFTPIKRFIA
                     FSTAYQLVTGLLLMILVVGSNIMLTIGESLILSMYFVYVRGHEGLFTPVVNYFGSRTI
                     SNFILCVIIPFISLNFLINTSIYLRRELDDWFNNSQGEFEDDDENTISKRVATNQEYQ
                     HPLSANYISMDSPDVINSSPGHFGMNSGQLLGNTTLYYGSLNGDDDDMTNDSALLRFC
                     KKLVKNWRALARNDSFVLGVMVSWSLLVFVTGILSTVYI"
     gene            <138291..>139205
                     /gene="PCL9"
                     /locus_tag="YDL179W"
                     /db_xref="GeneID:851375"
     mRNA            <138291..>139205
                     /gene="PCL9"
                     /locus_tag="YDL179W"
                     /product="Pcl9p"
                     /transcript_id="NM_001180239.1"
                     /db_xref="GI:296143191"
                     /db_xref="GeneID:851375"
     CDS             138291..139205
                     /gene="PCL9"
                     /locus_tag="YDL179W"
                     /note="Cyclin; forms a functional kinase complex with
                     Pho85p cyclin-dependent kinase (Cdk), expressed in late
                     M/early G1 phase, activated by Swi5p; PCL9 has a paralog,
                     PCL2, that arose from the whole genome duplication"
                     /codon_start=1
                     /product="Pcl9p"
                     /protein_id="NP_010102.1"
                     /db_xref="GI:6320022"
                     /db_xref="SGD:S000002338"
                     /db_xref="GeneID:851375"
                     /translation="MISDYDALLQFNKKPVSQEMIQFLATSTASIIKIRENNNPIQGC
                     RPPDLSIFIKNVVIQSNVQTPTLMATSVYLNKLKSVIPKNVYGINTTRHRIFLGCLIL
                     AAKTLNDSSPWNKHWTTYTEGLLRIREVNTIERELLEYLNWDVRITTPDLIDSLSYFL
                     GPIKEQLFLQRRQEMLLFNAPSPGQLKEYINHRRPVSHSRTSSAISVPSLTSMATVST
                     TDSRSSLLAKYQPSLPLVESDNFNKKNHVPLRNNNDICNNFRAEENIHSVNHIDVTMG
                     SSPVMSHKPTIHQRLNFTRRGWSSFFKQ"
     gene            <139522..>141114
                     /gene="DLD2"
                     /locus_tag="YDL178W"
                     /gene_synonym="AIP2"
                     /db_xref="GeneID:851376"
     mRNA            <139522..>141114
                     /gene="DLD2"
                     /locus_tag="YDL178W"
                     /gene_synonym="AIP2"
                     /product="Dld2p"
                     /transcript_id="NM_001180238.1"
                     /db_xref="GI:296143192"
                     /db_xref="GeneID:851376"
     CDS             139522..141114
                     /gene="DLD2"
                     /locus_tag="YDL178W"
                     /gene_synonym="AIP2"
                     /EC_number="1.1.2.4"
                     /note="D-lactate dehydrogenase; located in the
                     mitochondrial matrix"
                     /codon_start=1
                     /product="Dld2p"
                     /protein_id="NP_010103.1"
                     /db_xref="GI:6320023"
                     /db_xref="SGD:S000002337"
                     /db_xref="GeneID:851376"
                     /translation="MLRNILVRSTGSNFKFAGRYMKSSALLGYYRRVNYYSTKIQTRL
                     TSENYPDVHRDPRFKKLTSDDLNYFKSILSEQEILRASESEDLSFYNEDWMRKYKGQS
                     KLVLRPKSVEKVSLILNYCNDEKIAVVPQGGNTGLVGGSVPIFDELILSLANLNKIRD
                     FDPVSGILKCDAGVILENANNYVMEQNYMFPLDLGAKGSCHVGGVVATNAGGLRLLRY
                     GSLHGSVLGLEVVMPNGQIVNSMHSMRKDNTGYDLKQLFIGSEGTIGIITGVSILTVP
                     KPKAFNVSYLSVESFEDVQKVFVRARQELSEILSAFEFMDAKSQVLAKSQLKDAAFPL
                     EDEHPFYILIETSGSNKDHDDSKLETFLENVMEEGIVTDGVVAQDETELQNLWKWREM
                     IPEASQANGGVYKYDVSLPLKDLYSLVEATNARLSEAELVGDSPKPVVGAIGYGHVGD
                     GNLHLNVAVREYNKNIEKTLEPFVYEFVSSKHGSVSAEHGLGFQKKNYIGYSKSPEEV
                     KMMKDLKVHYDPNGILNPYKYI"
     gene            complement(<141209..>141721)
                     /locus_tag="YDL177C"
                     /db_xref="GeneID:851377"
     mRNA            complement(<141209..>141721)
                     /locus_tag="YDL177C"
                     /product="hypothetical protein"
                     /transcript_id="NM_001180237.1"
                     /db_xref="GI:296143193"
                     /db_xref="GeneID:851377"
     CDS             complement(141209..141721)
                     /locus_tag="YDL177C"
                     /note="hypothetical protein; similar to the mouse IMPACT
                     gene; YDL177C is not an essential gene"
                     /codon_start=1
                     /product="hypothetical protein"
                     /protein_id="NP_010104.1"
                     /db_xref="GI:6320024"
                     /db_xref="SGD:S000002336"
                     /db_xref="GeneID:851377"
                     /translation="MSKNVGKLVKIWNESEVLVDRKSKFQARCCPLQNQKDIPSILQE
                     LTQNNKSVSKASHMHMYAWRTAEVSNNLHLQQEQKKKGNKANKSNNSHVNKSRNITVQ
                     PKNIEQGCADCGEAGAGQRLLTLLERANIFNVLVIVTRWYGGTPLGSSRFRHISTCAV
                     ETLKKGGFLP"
     gene            <142097..>144223
                     /locus_tag="YDL176W"
                     /db_xref="GeneID:851378"
     mRNA            <142097..>144223
                     /locus_tag="YDL176W"
                     /product="hypothetical protein"
                     /transcript_id="NM_001180236.1"
                     /db_xref="GI:296143194"
                     /db_xref="GeneID:851378"
     CDS             142097..144223
                     /locus_tag="YDL176W"
                     /note="hypothetical protein; predicted by computational
                     methods to be involved in fructose-1,6-bisphosphatase
                     (Fbp1p) degradation; interacts with components of the GID
                     complex; YDL176W is not an essential gene"
                     /codon_start=1
                     /product="hypothetical protein"
                     /protein_id="NP_010105.1"
                     /db_xref="GI:6320025"
                     /db_xref="SGD:S000002335"
                     /db_xref="GeneID:851378"
                     /translation="MATGRIQFAVSTPCNTKGKPSGYRLFEFKNDRLALVPSERGCTK
                     VDVNANIQAFCYLRPNGRDTSISPDATHILDSCDYMVLAKSNGFIEIISNYQYKIKNG
                     LRLAPSYILRCTPEDFESNFFSDYMIAGLEYSQGLLYCCMCSGRIYVFVMNLPTDYIQ
                     YKNMYNPMFPDCFFKVHHDNNTTHSSEEEKLFEGSTRYTGRSCSKHICYFLLPIEPSH
                     LRSSPVVSSFCNMYQGLPIYRPSMYLHIERGISTFHINPLDRFCFMTVSPRSPLFIRK
                     IILPLTYVTFLSTFISLKNSIQGDTCGEILSWDNVAQQNGFGSLFSWISNKFTFDTDI
                     INSTIWDDIVKYSGTGMLDSGIVWKQRQGHAKDDIYELFHTQDMLGSSRRNSSFSTAS
                     SEPRPLSRRRRESFQALTRDAFRERMDVPCSTKWELDSFIRGLRRNTFMVDFEIVEKI
                     SHRNGNDGVNEDDNTTDESDETMTSFLTDNYKKMDIVCIDHFVTLSAFRPRYYDEPII
                     KIDSLSNKNGSENGTNEEEWAESQMKVDGQVIDDETAQFKQALGNLCSFKKLFMLDDS
                     LCFILDTHGVLLINRFEIKNTKNLLRNSKDTIRIIPHDFGLINDTIVIINDIDVGTDN
                     VCALTFHLVVTSMAGEITVLKGEFFKNCRLGRIKLCDSLKLNRKDRFVDKLALIDYDG
                     LNAQKRRLDYDEKDLYTFIVKKVKRD"
     gene            complement(<144484..>145518)
                     /gene="AIR2"
                     /locus_tag="YDL175C"
                     /db_xref="GeneID:851379"
     mRNA            complement(<144484..>145518)
                     /gene="AIR2"
                     /locus_tag="YDL175C"
                     /product="Air2p"
                     /transcript_id="NM_001180235.1"
                     /db_xref="GI:296143195"
                     /db_xref="GeneID:851379"
     CDS             complement(144484..145518)
                     /gene="AIR2"
                     /locus_tag="YDL175C"
                     /note="RNA-binding subunit of the TRAMP nuclear RNA
                     surveillance complex; involved in nuclear RNA processing
                     and degradation; involved in TRAMP complex assembly as a
                     bridge between Mtr4p and Trf4p; stimulates the poly(A)
                     polymerase activity of Pap2p in vitro; has 5 zinc knuckle
                     motifs; AIR2 has a paralog, AIR1, that arose from the
                     whole genome duplication; Air2p and Air1p have
                     nonredundant roles in regulation of substrate specificity
                     of the exosome"
                     /codon_start=1
                     /product="Air2p"
                     /protein_id="NP_010106.1"
                     /db_xref="GI:6320026"
                     /db_xref="SGD:S000002334"
                     /db_xref="GeneID:851379"
                     /translation="MEKNTAPFVVDTAPTTPPDKLVAPSIEEVNSNPNELRALRGQGR
                     YFGVSDDDKDAIKEAAPKCNNCSQRGHLKKDCPHIICSYCGATDDHYSRHCPKAIQCS
                     KCDEVGHYRSQCPHKWKKVQCTLCKSKKHSKERCPSIWRAYILVDDNEKAKPKVLPFH
                     TIYCYNCGGKGHFGDDCKEKRSSRVPNEDGSAFTGSNLSVELKQEYYRHMNRNSDENE
                     DYQFSESIYDEDPLPRPSHKRHSQNDHSHSGRNKRRASNFHPPPYQKSNVIQPTIRGE
                     TLSLNNNISKNSRYQNTKVNVSSISENMYGSRYNPSTYVDNNSISNSSNYRNYNSYQP
                     YRSGTLGKRR"
     gene            complement(<145826..>147589)
                     /gene="DLD1"
                     /locus_tag="YDL174C"
                     /db_xref="GeneID:851380"
     mRNA            complement(<145826..>147589)
                     /gene="DLD1"
                     /locus_tag="YDL174C"
                     /product="Dld1p"
                     /transcript_id="NM_001180234.1"
                     /db_xref="GI:296143196"
                     /db_xref="GeneID:851380"
     CDS             complement(145826..147589)
                     /gene="DLD1"
                     /locus_tag="YDL174C"
                     /EC_number="1.1.2.4"
                     /note="D-lactate dehydrogenase; oxidizes D-lactate to
                     pyruvate, transcription is heme-dependent, repressed by
                     glucose, and derepressed in ethanol or lactate; located in
                     the mitochondrial inner membrane"
                     /codon_start=1
                     /product="Dld1p"
                     /protein_id="NP_010107.1"
                     /db_xref="GI:6320027"
                     /db_xref="SGD:S000002333"
                     /db_xref="GeneID:851380"
                     /translation="MLWKRTCTRLIKPIAQPRGRLVRRSCYRYASTGTGSTDSSSQWL
                     KYSVIASSATLFGYLFAKNLYSRETKEDLIEKLEMVKKIDPVNSTLKLSSLDSPDYLH
                     DPVKIDKVVEDLKQVLGNKPENYSDAKSDLDAHSDTYFNTHHPSPEQRPRIILFPHTT
                     EEVSKILKICHDNNMPVVPFSGGTSLEGHFLPTRIGDTITVDLSKFMNNVVKFDKLDL
                     DITVQAGLPWEDLNDYLSDHGLMFGCDPGPGAQIGGCIANSCSGTNAYRYGTMKENII
                     NMTIVLPDGTIVKTKKRPRKSSAGYNLNGLFVGSEGTLGIVTEATVKCHVKPKAETVA
                     VVSFDTIKDAAACASNLTQSGIHLNAMELLDENMMKLINASESTDRCDWVEKPTMFFK
                     IGGRSPNIVNALVDEVKAVAQLNHCNSFQFAKDDDEKLELWEARKVALWSVLDADKSK
                     DKSAKIWTTDVAVPVSQFDKVIHETKKDMQASKLINAIVGHAGDGNFHAFIVYRTPEE
                     HETCSQLVDRMVKRALNAEGTCTGEHGVGIGKREYLLEELGEAPVDLMRKIKLAIDPK
                     RIMNPDKIFKTDPNEPANDYR"
     gene            <148191..>149078
                     /gene="PAR32"
                     /locus_tag="YDL173W"
                     /db_xref="GeneID:851381"
     mRNA            <148191..>149078
                     /gene="PAR32"
                     /locus_tag="YDL173W"
                     /product="Par32p"
                     /transcript_id="NM_001180233.1"
                     /db_xref="GI:296143197"
                     /db_xref="GeneID:851381"
     CDS             148191..149078
                     /gene="PAR32"
                     /locus_tag="YDL173W"
                     /note="hypothetical protein; hyperphosphorylated upon
                     rapamycin treatment in a Tap42p-dependent manner; green
                     fluorescent protein (GFP)-fusion protein localizes to the
                     cytoplasm; PAR32 is not an essential gene"
                     /codon_start=1
                     /product="Par32p"
                     /protein_id="NP_010108.1"
                     /db_xref="GI:6320028"
                     /db_xref="SGD:S000002332"
                     /db_xref="GeneID:851381"
                     /translation="MATFNPQNEMENQARVQEYKVSTGRGGAGNIHKSMSKPSPVLLP
                     LKSNSKTVANNNNNGSNQEKVPRFAIGRGGAGNIFHDPHLTRSAQQLDSNDNINYNDV
                     INDIDDYISPITSDMVDEGGSNPVTNTRSRISATRSHQSLHATTSSPNNNAPIVVGRG
                     GAGNIFFNKKKVASNGGNEEDEIRGGNIEDEDTINANEDNLFVVTSNGNALAAIKSTS
                     KKPKNKLKGKSAPEKFAIGRGGAGNIISPKSSRNTINHNLNDDDEDKFNLKDDNGKEK
                     KKKKKKKSGFFSSLKTMFN"
     gene            complement(<149203..>155640)
                     /gene="GLT1"
                     /locus_tag="YDL171C"
                     /db_xref="GeneID:851383"
     mRNA            complement(<149203..>155640)
                     /gene="GLT1"
                     /locus_tag="YDL171C"
                     /product="glutamate synthase (NADH)"
                     /transcript_id="NM_001180231.1"
                     /db_xref="GI:296143198"
                     /db_xref="GeneID:851383"
     CDS             complement(149203..155640)
                     /gene="GLT1"
                     /locus_tag="YDL171C"
                     /EC_number="1.4.1.14"
                     /note="NAD(+)-dependent glutamate synthase (GOGAT);
                     synthesizes glutamate from glutamine and
                     alpha-ketoglutarate; with Gln1p, forms the secondary
                     pathway for glutamate biosynthesis from ammonia;
                     expression regulated by nitrogen source; assembles into
                     filaments as cells approach stationary phase and under
                     cytosolic acidification and starvation conditions"
                     /codon_start=1
                     /product="glutamate synthase (NADH)"
                     /protein_id="NP_010110.1"
                     /db_xref="GI:6320030"
                     /db_xref="SGD:S000002330"
                     /db_xref="GeneID:851383"
                     /translation="MPVLKSDNFDPLEEAYEGGTIQNYNDEHHLHKSWANVIPDKRGL
                     YDPDYEHDACGVGFVANKHGEQSHKIVTDARYLLVNMTHRGAVSSDGNGDGAGILLGI
                     PHEFMKREFKLDLDLDIPEMGKYAVGNVFFKKNEKNNKKNLIKCQKIFEDLAASFNLS
                     VLGWRNVPVDSTILGDVALSREPTILQPLLVPLYDEKQPEFNETKFRTQLYLLRKEAS
                     LQIGLENWFYVCSLNNTTIVYKGQLTPAQVYNYYPDLTNAHFKSHMALVHSRFSTNTF
                     PSWDRAQPLRWLAHNGEINTLRGNKNWMRSREGVMNSATFKDELDKLYPIIEEGGSDS
                     AALDNVLELLTINGTLSLPEAVMMMVPEAYHKDMDSDLKAWYDWAACLMEPWDGPALL
                     TFTDGRYCGAILDRNGLRPCRYYITSDDRVICASEVGVIPIENSLVVQKGKLKPGDLF
                     LVDTQLGEMVDTKKLKSQISKRQDFKSWLSKVIKLDDLLSKTANLVPKEFISQDSLSL
                     KVQSDPRLLANGYTFEQVTFLLTPMALTGKEALGSMGNDAPLACLNENPVLLYDYFRQ
                     LFAQVTNPPIDPIREANVMSLECYVGPQGNLLEMHSSQCDRLLLKSPILHWNEFQALK
                     NIEAAYPSWSVAEIDITFDKSEGLLGYTDTIDKITKLASEAIDDGKKILIITDRKMGA
                     NRVSISSLIAISCIHHHLIRNKQRSQVALILETGEAREIHHFCVLLGYGCDGVYPYLA
                     METLVRMNREGLLRNVNNDNDTLEEGQILENYKHAIDAGILKVMSKMGISTLASYKGA
                     QIFEALGLDNSIVDLCFTGTSSRIRGVTFEYLAQDAFSLHERGYPSRQTISKSVNLPE
                     SGEYHFRDGGYKHVNEPTAIASLQDTVRNKNDVSWQLYVKKEMEAIRDCTLRGLLELD
                     FENSVSIPLEQVEPWTEIARRFASGAMSYGSISMEAHSTLAIAMNRLGAKSNCGEGGE
                     DAERSAVQENGDTMRSAIKQVASARFGVTSYYLSDADEIQIKIAQGAKPGEGGELPAH
                     KVSKDIAKTRHSTPNVGLISPPPHHDIYSIEDLKQLIYDLKCANPRAGISVKLVSEVG
                     VGIVASGVAKAKADHILVSGHDGGTGAARWTSVKYAGLPWELGLAETHQTLVLNDLRR
                     NVVVQTDGQLRTGFDIAVAVLLGAESFTLATVPLIAMGCVMLRRCHLNSCAVGIATQD
                     PYLRSKFKGQPEHVINFFYYLIQDLRQIMAKLGFRTIDEMVGHSEKLKKRDDVNAKAI
                     NIDLSPILTPAHVIRPGVPTKFTKKQDHKLHTRLDNKLIDEAEVTLDRGLPVNIDASI
                     INTDRALGSTLSYRVSKKFGEDGLPKDTVVVNIEGSAGQSFGAFLASGITFILNGDAN
                     DYVGKGLSGGIIVIKPPKDSKFKSDENVIVGNTCFYGATSGTAFISGSAGERFGVRNS
                     GATIVVERIKGNNAFEYMTGGRAIVLSQMESLNAFSGATGGIAYCLTSDYDDFVGKIN
                     KDTVELESLCDPVEIAFVKNLIQEHWNYTQSDLAARILGNFNHYLKDFVKVIPTDYKK
                     VLLKEKAEAAKAKAKATSEYLKKFRSNQEVDDEVNTLLIANQKAKEQEKKKSITISNK
                     ATLKEPKVVDLEDAVPDSKQLEKNSERIEKTRGFMIHKRRHETHRDPRTRVNDWKEFT
                     NPITKKDAKYQTARCMDCGTPFCLSDTGCPLSNIIPKFNELLFKNQWKLALDKLLETN
                     NFPEFTGRVCPAPCEGACTLGIIEDPVGIKSVERIIIDNAFKEGWIKPCPPSTRTGFT
                     VGVIGSGPAGLACADMLNRAGHTVTVYERSDRCGGLLMYGIPNMKLDKAIVQRRIDLL
                     SAEGIDFVTNTEIGKTISMDELKNKHNAVVYAIGSTIPRDLPIKGRELKNIDFAMQLL
                     ESNTKALLNKDLEIIREKIQGKKVIVVGGGDTGNDCLGTSVRHGAASVLNFELLPEPP
                     VERAKDNPWPQWPRVMRVDYGHAEVKEHYGRDPREYCILSKEFIGNDEGEVTAIRTVR
                     VEWKKSQSGVWQMVEIPNSEEIFEADIILLSMGFVGPELINGNDNEVKKTRRGTIATL
                     DDSSYSIDGGKTFACGDCRRGQSLIVWAIQEGRKCAASVDKFLMDGTTYLPSNGGIVQ
                     RDYKLLKELASQV"
     gene            <156318..>157904
                     /gene="UGA3"
                     /locus_tag="YDL170W"
                     /db_xref="GeneID:851384"
     mRNA            <156318..>157904
                     /gene="UGA3"
                     /locus_tag="YDL170W"
                     /product="Uga3p"
                     /transcript_id="NM_001180230.1"
                     /db_xref="GI:296143199"
                     /db_xref="GeneID:851384"
     CDS             156318..157904
                     /gene="UGA3"
                     /locus_tag="YDL170W"
                     /note="Transcriptional activator for GABA-dependent
                     induction of GABA genes; binds to DNA elements found in
                     the promoters of target genes and increases their
                     expression in the presence of GABA (gamma-aminobutyrate);
                     zinc finger transcription factor of the Zn(2)-Cys(6)
                     binuclear cluster domain type; localized to the nucleus;
                     examples of GABA genes include UGA1, UGA2, and UGA4"
                     /codon_start=1
                     /product="Uga3p"
                     /protein_id="NP_010111.1"
                     /db_xref="GI:6320031"
                     /db_xref="SGD:S000002329"
                     /db_xref="GeneID:851384"
                     /translation="MNYGVEKLKLKYSKHGCITCKIRKKRCSEDKPVCRDCRRLSFPC
                     IYISESVDKQSLKKIKADIQHQLISKKRKHAPDSAQKAAVATRTRRVGSDEQDNQVYL
                     SKPLEDCISQKLDSMGLQLYNYYRSHLANIISIAPMNQNYYLNIFLPMAHENDGILFA
                     ILAWSANHLSISSSNELRKDEIFVNLANKYTYMSLSHLKTNEGSSACAKLGFLYSLAQ
                     ILILCGSEICQGDVKFWKILLNIGKNLIENHVGKDVSRILTTTTEEPSLEERIIFPNF
                     NSVVKYWLIVNFIYHDILNFNTTSFPIEQYEKFFQRDQNSLPSSANFIESIDSPIEEI
                     DPLIGINKPILLLLGQVTNLTRFLQTMEQEEMLEHGDKILSLQVEIYKLQPSLMALEH
                     LDDEKKFYYLELFEIMKISTLMFFQLTLLKIDKDSLELQILRNKLDSKLDKVIGTFLE
                     GSLCFPLFIYGVCIQVEDMEKKIDLEAKFDDILKRYKCYNFQNARLLIRKIWQNEADG
                     ISEHDLVHMIDELDYNINFA"
     gene            complement(<158064..>158735)
                     /gene="UGX2"
                     /locus_tag="YDL169C"
                     /db_xref="GeneID:851385"
     mRNA            complement(<158064..>158735)
                     /gene="UGX2"
                     /locus_tag="YDL169C"
                     /product="Ugx2p"
                     /transcript_id="NM_001180229.1"
                     /db_xref="GI:296143200"
                     /db_xref="GeneID:851385"
     CDS             complement(158064..158735)
                     /gene="UGX2"
                     /locus_tag="YDL169C"
                     /note="hypothetical protein; transcript accumulates in
                     response to any combination of stress conditions"
                     /codon_start=1
                     /product="Ugx2p"
                     /protein_id="NP_010112.1"
                     /db_xref="GI:6320032"
                     /db_xref="SGD:S000002328"
                     /db_xref="GeneID:851385"
                     /translation="MEDKEKLIVYSNTSSVFTYSAEIRPNFKISVSQSQGFAWNQDLF
                     ATQYQQSYKVVYDAHEDNFDELILKIKGKLKTKSNKRAKMKSKTKLTRTAKQRRESPV
                     CERDESDEDNDSDHYQRIQVLDGHEFPRANRYKSVWAHDVHSNEDSTSDGESNHDIDM
                     IGGTGTSYAGAAIMDRPRRKSERSISFVEDSKTGDYRYQTGQVDVVEVDSDTPENNHL
                     KWLIK"
     gene            <159604..>160764
                     /gene="SFA1"
                     /locus_tag="YDL168W"
                     /gene_synonym="ADH5"
                     /db_xref="GeneID:851386"
     mRNA            <159604..>160764
                     /gene="SFA1"
                     /locus_tag="YDL168W"
                     /gene_synonym="ADH5"
                     /product="bifunctional alcohol
                     dehydrogenase/S-(hydroxymethyl)glutathione dehydrogenase"
                     /transcript_id="NM_001180228.1"
                     /db_xref="GI:296143201"
                     /db_xref="GeneID:851386"
     CDS             159604..160764
                     /gene="SFA1"
                     /locus_tag="YDL168W"
                     /gene_synonym="ADH5"
                     /EC_number="1.1.1.-"
                     /EC_number="1.1.1.284"
                     /EC_number="1.1.1.1"
                     /note="Bifunctional alcohol dehydrogenase and formaldehyde
                     dehydrogenase; formaldehyde dehydrogenase activity is
                     glutathione-dependent; functions in formaldehyde
                     detoxification and formation of long chain and complex
                     alcohols, regulated by Hog1p-Sko1p; protein abundance
                     increases in response to DNA replication stress"
                     /codon_start=1
                     /product="bifunctional alcohol
                     dehydrogenase/S-(hydroxymethyl)glutathione dehydrogenase"
                     /protein_id="NP_010113.1"
                     /db_xref="GI:6320033"
                     /db_xref="SGD:S000002327"
                     /db_xref="GeneID:851386"
                     /translation="MSAATVGKPIKCIAAVAYDAKKPLSVEEITVDAPKAHEVRIKIE
                     YTAVCHTDAYTLSGSDPEGLFPCVLGHEGAGIVESVGDDVITVKPGDHVIALYTAECG
                     KCKFCTSGKTNLCGAVRATQGKGVMPDGTTRFHNAKGEDIYHFMGCSTFSEYTVVADV
                     SVVAIDPKAPLDAACLLGCGVTTGFGAALKTANVQKGDTVAVFGCGTVGLSVIQGAKL
                     RGASKIIAIDINNKKKQYCSQFGATDFVNPKEDLAKDQTIVEKLIEMTDGGLDFTFDC
                     TGNTKIMRDALEACHKGWGQSIIIGVAAAGEEISTRPFQLVTGRVWKGSAFGGIKGRS
                     EMGGLIKDYQKGALKVEEFITHRRPFKEINQAFEDLHNGDCLRTVLKSDEIK"
     gene            complement(<160995..>163154)
                     /gene="NRP1"
                     /locus_tag="YDL167C"
                     /db_xref="GeneID:851387"
     mRNA            complement(<160995..>163154)
                     /gene="NRP1"
                     /locus_tag="YDL167C"
                     /product="Nrp1p"
                     /transcript_id="NM_001180227.1"
                     /db_xref="GI:296143202"
                     /db_xref="GeneID:851387"
     CDS             complement(160995..163154)
                     /gene="NRP1"
                     /locus_tag="YDL167C"
                     /note="Putative RNA binding hypothetical protein;
                     localizes to stress granules induced by glucose
                     deprivation; predicted to be involved in ribosome
                     biogenesis"
                     /codon_start=1
                     /product="Nrp1p"
                     /protein_id="NP_010114.1"
                     /db_xref="GI:6320034"
                     /db_xref="SGD:S000002326"
                     /db_xref="GeneID:851387"
                     /translation="MHYVVLELQVAHLPDTPKDQCRIANIAFQIVNAETLVCHYGTNS
                     LPSIEVNGTTKSLESAMVQLDKDIHDVIGNDDFVLVSLYSTWHIRVTLPRQARDDGFI
                     LTSYLQHPKVFDLWKEFDRWCVNHPEILGQKKAISNNNCNTKSISINAAKNTKDLDEI
                     VRILEVSIPTEEAGSVPEIYSLLKRTTDILIQLHKKCTSPEDMESVLTKPYDSHTDIR
                     AFLQEKSKILYMNNLPPDTTQSELESWFTQYGVRPVGFWTVKNIVEDTSNVNNNWSLN
                     NSPYVEDQDSISGFVVFQTHEEATEVLALNGRSILSNLANTKQPRVVEHVLELQPSST
                     GVLDKAQEILSPFPQSKNKPRPGDWNCPSCGFSNFQRRTACFRCSFPAPSNSQIHTAN
                     SNNNVNSSRNNLNNRVNSGSSSNISNTAANHPYGAPEFNMIANNTPAALTYNRAHFPA
                     ITPLSRQNSLNMAPSNSGSPIIIADHFSGNNNIAPNYRYNNNINNNNNNINNMTNNRY
                     NINNNINGNGNGNGNNSNNNNNHNNNHNNNHHNGSINSNSNTNNNNNNNNGNNSNNCN
                     SNIGMGGCGSNMPFRAGDWKCSTCTYHNFAKNVVCLRCGGPKSISGDASETNHYIDSS
                     TFGPASRTPSNNNISVNTNGGSNAGRTDGNDNKGRDISLMEFMSPPLSMATKSMKEGD
                     GNGSSFNEFKSDKANVNFSNVGDNSAFGNGFNSSIRW"
     gene            complement(<163449..>164042)
                     /gene="FAP7"
                     /locus_tag="YDL166C"
                     /db_xref="GeneID:851388"
     mRNA            complement(<163449..>164042)
                     /gene="FAP7"
                     /locus_tag="YDL166C"
                     /product="Fap7p"
                     /transcript_id="NM_001180226.1"
                     /db_xref="GI:296143203"
                     /db_xref="GeneID:851388"
     CDS             complement(163449..164042)
                     /gene="FAP7"
                     /locus_tag="YDL166C"
                     /EC_number="2.7.4.3"
                     /note="Essential NTPase required for small ribosome
                     subunit synthesis; mediates processing of the 20S pre-rRNA
                     at site D in the cytoplasm but associates only transiently
                     with 43S preribosomes via Rps14p, may be the endonuclease
                     for site D; depletion leads to accumulation of pre-40S
                     ribosomes in 80S-like ribosomes"
                     /codon_start=1
                     /product="Fap7p"
                     /protein_id="NP_010115.1"
                     /db_xref="GI:6320035"
                     /db_xref="SGD:S000002325"
                     /db_xref="GeneID:851388"
                     /translation="MEARRYGPNIIVTGTPGCGKSSTCEFLKNKLKDYKYYNISDFAK
                     DNDCFEGYDEGRKSHIVDEDKLLDMLEPLLRQGNSIVDWHVNDVFPERLIDLVVVLRC
                     DNSNLYSRLHARGYHDSKIEENLDAEIMGVVKQDAVESYEPHIVVELQSDTKEDMVSN
                     VSRIVAWEKMWLEQHPDGVTNEYQGPRSDDEDDEDSE"
     gene            <164290..>164865
                     /gene="CDC36"
                     /locus_tag="YDL165W"
                     /gene_synonym="DNA19; NOT2"
                     /db_xref="GeneID:851389"
     mRNA            <164290..>164865
                     /gene="CDC36"
                     /locus_tag="YDL165W"
                     /gene_synonym="DNA19; NOT2"
                     /product="CCR4-NOT core subunit CDC36"
                     /transcript_id="NM_001180225.1"
                     /db_xref="GI:296143204"
                     /db_xref="GeneID:851389"
     CDS             164290..164865
                     /gene="CDC36"
                     /locus_tag="YDL165W"
                     /gene_synonym="DNA19; NOT2"
                     /note="Component of the CCR4-NOT core complex; this
                     complex has multiple roles in regulating mRNA levels
                     including regulation of transcription and destabilizing
                     mRNAs through deadenylation; basal transcription factor"
                     /codon_start=1
                     /product="CCR4-NOT core subunit CDC36"
                     /protein_id="NP_010116.1"
                     /db_xref="GI:6320036"
                     /db_xref="SGD:S000002324"
                     /db_xref="GeneID:851389"
                     /translation="MEKFGLKALVPLLKLEDKELSSTYDHSMTLGADLSSMLYSLGIP
                     RDSQDHRVLDTFQSPWAETSRSEVEPRFFTPESFTNIPGVLQSTVTPPCFNSIQNDQQ
                     RVALFQDETLFFLFYKHPGTVIQELTYLELRKRNWRYHKTLKAWLTKDPMMEPIVSAD
                     GLSERGSYVFFDPQRWEKCQRDFLLFYNAIM"
     gene            complement(<164987..>167254)
                     /gene="CDC9"
                     /locus_tag="YDL164C"
                     /gene_synonym="MMS8"
                     /db_xref="GeneID:851391"
     mRNA            complement(<164987..>167254)
                     /gene="CDC9"
                     /locus_tag="YDL164C"
                     /gene_synonym="MMS8"
                     /product="DNA ligase (ATP) CDC9"
                     /transcript_id="NM_001180224.1"
                     /db_xref="GI:296143205"
                     /db_xref="GeneID:851391"
     CDS             complement(164987..167254)
                     /gene="CDC9"
                     /locus_tag="YDL164C"
                     /gene_synonym="MMS8"
                     /EC_number="6.5.1.1"
                     /note="DNA ligase found in the nucleus and mitochondria;
                     an essential enzyme that joins Okazaki fragments during
                     DNA replication; also acts in ribonucleotide excision
                     repair, base excision repair, and recombination"
                     /codon_start=1
                     /product="DNA ligase (ATP) CDC9"
                     /protein_id="NP_010117.1"
                     /db_xref="GI:6320038"
                     /db_xref="SGD:S000002323"
                     /db_xref="GeneID:851391"
                     /translation="MRRLLTGCLLSSARPLKSRLPLLMSSSLPSSAGKKPKQATLARF
                     FTSMKNKPTEGTPSPKKSSKHMLEDRMDNVSGEEEYATKKLKQTAVTHTVAAPSSMGS
                     NFSSIPSSAPSSGVADSPQQSQRLVGEVEDALSSNNNDHYSSNIPYSEVCEVFNKIEA
                     ISSRLEIIRICSDFFIKIMKQSSKNLIPTTYLFINRLGPDYEAGLELGLGENLLMKTI
                     SETCGKSMSQIKLKYKDIGDLGEIAMGARNVQPTMFKPKPLTVGEVFKNLRAIAKTQG
                     KDSQLKKMKLIKRMLTACKGIEAKFLIRSLESKLRIGLAEKTVLISLSKALLLHDENR
                     EDSPDKDVPMDVLESAQQKIRDAFCQVPNYEIVINSCLEHGIMNLDKYCTLRPGIPLK
                     PMLAKPTKAINEVLDRFQGETFTSEYKYDGERAQVHLLNDGTMRIYSRNGENMTERYP
                     EINITDFIQDLDTTKNLILDCEAVAWDKDQGKILPFQVLSTRKRKDVELNDVKVKVCL
                     FAFDILCYNDERLINKSLKERREYLTKVTKVVPGEFQYATQITTNNLDELQKFLDESV
                     NHSCEGLMVKMLEGPESHYEPSKRSRNWLKLKKDYLEGVGDSLDLCVLGAYYGRGKRT
                     GTYGGFLLGCYNQDTGEFETCCKIGTGFSDEMLQLLHDRLTPTIIDGPKATFVFDSSA
                     EPDVWFEPTTLFEVLTADLSLSPIYKAGSATFDKGVSLRFPRFLRIREDKGVEDATSS
                     DQIVELYENQSHMQN"
     gene            <167714..>169078
                     /gene="ENT1"
                     /locus_tag="YDL161W"
                     /db_xref="GeneID:851392"
     mRNA            <167714..>169078
                     /gene="ENT1"
                     /locus_tag="YDL161W"
                     /product="Ent1p"
                     /transcript_id="NM_001180221.1"
                     /db_xref="GI:296143206"
                     /db_xref="GeneID:851392"
     CDS             167714..169078
                     /gene="ENT1"
                     /locus_tag="YDL161W"
                     /note="Epsin-like protein involved in endocytosis and
                     actin patch assembly; functionally redundant with Ent2p;
                     binds clathrin via a clathrin-binding domain motif at
                     C-terminus; relocalizes from bud neck to cytoplasm upon
                     DNA replication stress; ENT1 has a paralog, ENT2, that
                     arose from the whole genome duplication"
                     /codon_start=1
                     /product="Ent1p"
                     /protein_id="NP_010120.1"
                     /db_xref="GI:6320039"
                     /db_xref="SGD:S000002320"
                     /db_xref="GeneID:851392"
                     /translation="MSKQFVRSAKNLVKGYSSTQVLVRNATSNDNHQVSKDSLIELAE
                     KSYDSADFFEIMDMLDKRLNDKGKYWRHIAKALTVIDYLIRFGSENCVLWCRENLYII
                     KTLKEFRHEDDEGIDQGQIVRVKAKELTALLSDDERLNEERNMNIKGRNRKGRRRRGT
                     GRSDENDDDLQRAISASRLTAEEDERRRKQDEDYETALQLSKEEEELKRLQDLQRMQQ
                     QQGQQQLQQPMYYDIFGNPITPEEYAQFQLQQQQQQQQQQLQQQPMYYDVFGNPITPE
                     ELAQFQQQQQLQEQQYLASMQQQQQAMSNNPFAKSEQSSSSPKRNQLVAASSPQQLQQ
                     QKQQEPLIQNRTGNQSMTDKYSKLNELLATGTGIDTFGNVGEARIPAQHTKTGTFINS
                     QGTGYRQVSDDPNHNPFLNSQYTGLPSTSVVPTQTGYGFGNQSQQQSQNNGSNNRGYT
                     LIDL"
     gene            complement(<169366..>169608)
                     /gene="MHF2"
                     /locus_tag="YDL160C-A"
                     /db_xref="GeneID:1466431"
     mRNA            complement(<169366..>169608)
                     /gene="MHF2"
                     /locus_tag="YDL160C-A"
                     /product="Mhf2p"
                     /transcript_id="NM_001184530.1"
                     /db_xref="GI:296143207"
                     /db_xref="GeneID:1466431"
     CDS             complement(169366..169608)
                     /gene="MHF2"
                     /locus_tag="YDL160C-A"
                     /note="Component of the heterotetrameric MHF histone-fold
                     complex; in humans the MMF complex interacts with both DNA
                     and Mph1p ortholog FANCM to stabilize and remodel blocked
                     replication forks and repair damaged DNA; mhf2 srs2 double
                     mutants are MMS hypersensitive; orthologous to human
                     centromere constitutive-associated network (CCAN) subunit
                     CENP-X, also known as MHF2"
                     /codon_start=1
                     /product="Mhf2p"
                     /protein_id="NP_878060.1"
                     /db_xref="GI:33438778"
                     /db_xref="SGD:S000028520"
                     /db_xref="GeneID:1466431"
                     /translation="MLSKEALIKILSQNEGGNDMKIADEVVPMIQKYLDIFIDEAVLR
                     SLQSHKDINGERGDKSPLELSHQDLERIVGLLLMDM"
     gene            complement(<170410..>171930)
                     /gene="DHH1"
                     /locus_tag="YDL160C"
                     /db_xref="GeneID:851394"
     mRNA            complement(<170410..>171930)
                     /gene="DHH1"
                     /locus_tag="YDL160C"
                     /product="DExD/H-box ATP-dependent RNA helicase DHH1"
                     /transcript_id="NM_001180220.1"
                     /db_xref="GI:296143208"
                     /db_xref="GeneID:851394"
     CDS             complement(170410..171930)
                     /gene="DHH1"
                     /locus_tag="YDL160C"
                     /EC_number="3.6.4.13"
                     /note="Cytoplasmic DExD/H-box helicase, stimulates mRNA
                     decapping; coordinates distinct steps in mRNA function and
                     decay, interacts with both the decapping and deadenylase
                     complexes, role in translational repression, mRNA decay,
                     and processing body dynamics; may have a role in mRNA
                     export; C-terminus of Dhh1p interacts with Ngr1p and
                     promotes POR1, but not EDC1 mRNA decay; forms cytoplasmic
                     foci upon DNA replication stress"
                     /codon_start=1
                     /product="DExD/H-box ATP-dependent RNA helicase DHH1"
                     /protein_id="NP_010121.1"
                     /db_xref="GI:6320041"
                     /db_xref="SGD:S000002319"
                     /db_xref="GeneID:851394"
                     /translation="MGSINNNFNTNNNSNTDLDRDWKTALNIPKKDTRPQTDDVLNTK
                     GNTFEDFYLKRELLMGIFEAGFEKPSPIQEEAIPVAITGRDILARAKNGTGKTAAFVI
                     PTLEKVKPKLNKIQALIMVPTRELALQTSQVVRTLGKHCGISCMVTTGGTNLRDDILR
                     LNETVHILVGTPGRVLDLASRKVADLSDCSLFIMDEADKMLSRDFKTIIEQILSFLPP
                     THQSLLFSATFPLTVKEFMVKHLHKPYEINLMEELTLKGITQYYAFVEERQKLHCLNT
                     LFSKLQINQAIIFCNSTNRVELLAKKITDLGYSCYYSHARMKQQERNKVFHEFRQGKV
                     RTLVCSDLLTRGIDIQAVNVVINFDFPKTAETYLHRIGRSGRFGHLGLAINLINWNDR
                     FNLYKIEQELGTEIAAIPATIDKSLYVAENDETVPVPFPIEQQSYHQQAIPQQQLPSQ
                     QQFAIPPQQHHPQFMVPPSHQQQQAYPPPQMPSQQGYPPQQEHFMAMPPGQSQPQY"
     gene            <172182..>172313
                     /locus_tag="YDL159W-A"
                     /gene_synonym="YDL159W-B"
                     /db_xref="GeneID:851395"
     mRNA            <172182..>172313
                     /locus_tag="YDL159W-A"
                     /gene_synonym="YDL159W-B"
                     /product="hypothetical protein"
                     /transcript_id="NM_001184465.1"
                     /db_xref="GI:296143209"
                     /db_xref="GeneID:851395"
     CDS             172182..172313
                     /locus_tag="YDL159W-A"
                     /gene_synonym="YDL159W-B"
                     /note="hypothetical protein; identified by sequence
                     comparison with hemiascomycetous yeast species"
                     /codon_start=1
                     /product="hypothetical protein"
                     /protein_id="NP_076884.1"
                     /db_xref="GI:13129162"
                     /db_xref="SGD:S000007599"
                     /db_xref="GeneID:851395"
                     /translation="MYNQIINTFIDDCLFLQTPMLQSPISSKIVLSFFLRNFFPSLF"
     gene            <172481..>174028
                     /gene="STE7"
                     /locus_tag="YDL159W"
                     /db_xref="GeneID:851396"
     mRNA            <172481..>174028
                     /gene="STE7"
                     /locus_tag="YDL159W"
                     /product="Ste7p"
                     /transcript_id="NM_001180219.1"
                     /db_xref="GI:296143210"
                     /db_xref="GeneID:851396"
     CDS             172481..174028
                     /gene="STE7"
                     /locus_tag="YDL159W"
                     /EC_number="2.7.12.2"
                     /note="Signal transducing MAP kinase kinase; involved in
                     pheromone response where it phosphorylates Fus3p; involved
                     in the pseudohyphal/invasive growth pathway where it
                     phosphorylates of Kss1p; phosphorylated by Ste11p;
                     degraded by ubiquitin pathway"
                     /codon_start=1
                     /product="Ste7p"
                     /protein_id="NP_010122.1"
                     /db_xref="GI:6320042"
                     /db_xref="SGD:S000002318"
                     /db_xref="GeneID:851396"
                     /translation="MFQRKTLQRRNLKGLNLNLHPDVGNNGQLQEKTETHQGQSRIEG
                     HVMSNINAIQNNSNLFLRRGIKKKLTLDAFGDDQAISKPNTVVIQQPQNEPVLVLSSL
                     SQSPCVSSSSSLSTPCIIDAYSNNFGLSPSSTNSTPSTIQGLSNIATPVENEHSISLP
                     PLEESLSPAAADLKDTLSGTSNGNYIQLQDLVQLGKIGAGNSGTVVKALHVPDSKIVA
                     KKTIPVEQNNSTIINQLVRELSIVKNVKPHENIITFYGAYYNQHINNEIIILMEYSDC
                     GSLDKILSVYKRFVQRGTVSSKKTWFNELTISKIAYGVLNGLDHLYRQYKIIHRDIKP
                     SNVLINSKGQIKLCDFGVSKKLINSIADTFVGTSTYMSPERIQGNVYSIKGDVWSLGL
                     MIIELVTGEFPLGGHNDTPDGILDLLQRIVNEPSPRLPKDRIYSKEMTDFVNRCCIKN
                     ERERSSIHELLHHDLIMKYVSPSKDDKFRHWCRKIKSKIKEDKRIKREALDRAKLEKK
                     QSERSTH"
     gene            complement(<174232..>174588)
                     /locus_tag="YDL157C"
                     /db_xref="GeneID:851398"
     mRNA            complement(<174232..>174588)
                     /locus_tag="YDL157C"
                     /product="hypothetical protein"
                     /transcript_id="NM_001180217.1"
                     /db_xref="GI:296143211"
                     /db_xref="GeneID:851398"
     CDS             complement(174232..174588)
                     /locus_tag="YDL157C"
                     /note="hypothetical protein; the authentic, non-tagged
                     protein is detected in highly purified mitochondria in
                     high-throughput studies"
                     /codon_start=1
                     /product="hypothetical protein"
                     /protein_id="NP_010124.1"
                     /db_xref="GI:6320044"
                     /db_xref="SGD:S000002316"
                     /db_xref="GeneID:851398"
                     /translation="MSNILAVFNPPPQRELEKEETMDCVPCQVMSTMFSVGFGSYLAS
                     GKPFKYGKKEAKRGISLTEFEKRNPQWWKVTLRSFGGLLIAFGFVRGTEGWLWHKNKE
                     YKNYKKLSNDGETQAN"
     gene            <174918..>176486
                     /gene="CMR1"
                     /locus_tag="YDL156W"
                     /db_xref="GeneID:851399"
     mRNA            <174918..>176486
                     /gene="CMR1"
                     /locus_tag="YDL156W"
                     /product="Cmr1p"
                     /transcript_id="NM_001180216.1"
                     /db_xref="GI:296143212"
                     /db_xref="GeneID:851399"
     CDS             174918..176486
                     /gene="CMR1"
                     /locus_tag="YDL156W"
                     /note="DNA-binding protein with preference for UV-damaged
                     DNA; protein sequence contains three WD domains (WD-40
                     repeat); green fluorescent protein (GFP)-fusion protein
                     localizes to the cytoplasm and nucleus; potential
                     regulatory target of Mbp1p, which binds to the promoter
                     region; co-localizes with Hos2p in nuclear foci in
                     response to DNA damage by MMS"
                     /codon_start=1
                     /product="Cmr1p"
                     /protein_id="NP_010125.1"
                     /db_xref="GI:6320045"
                     /db_xref="SGD:S000002315"
                     /db_xref="GeneID:851399"
                     /translation="MPELTEFQKKRLENIKRNNDLLKKLHLSGVASQIKHEAGVLEKS
                     RAPAKKKQKTTNTRATKSASPTLPTRRSRRLRGESADDVKGIPNVNDNQLLKMGSPDG
                     QDKNFIDAIKEKPVIGDVKLSDLIKDEDESALLEKFKRFNNGNFSSGDFFEEIKKRQG
                     DVTGMDEFDLDLYDVFQPNEIKITYERISATYFHPAMEKKLIIAGDTSGTVGFWNVRD
                     EPLADSEEDRMEEPDITRVKLFTKNVGRIDCFPADTSKILLTSYDGSIRSVHLNNLQS
                     EEVLTLKNEYDDSLGISDCQFSYENPNVLFLTTLGGEFTTFDTRVKKSEYNLRRLADK
                     KIGSMAINPMRPYEIATGSLDRTLKIWDTRNLVKKPEWSQYEDYPSHEIVSTYDSRLS
                     VSAVSYSPTDGTLVCNGYDDTIRLFDVKSRDHLSAKLEPKLTIQHNCQTGRWTSILKA
                     RFKPNKNVFAIANMKRAIDIYNSEGQQLAHLPTATVPAVISWHPLRNWIAGGNSSGKI
                     FLFTDDSGTIKQEE"
     gene            <176773..>178056
                     /gene="CLB3"
                     /locus_tag="YDL155W"
                     /db_xref="GeneID:851400"
     mRNA            <176773..>178056
                     /gene="CLB3"
                     /locus_tag="YDL155W"
                     /product="Clb3p"
                     /transcript_id="NM_001180215.1"
                     /db_xref="GI:296143213"
                     /db_xref="GeneID:851400"
     CDS             176773..178056
                     /gene="CLB3"
                     /locus_tag="YDL155W"
                     /note="B-type cyclin involved in cell cycle progression;
                     activates Cdc28p to promote the G2/M transition; may be
                     involved in DNA replication and spindle assembly;
                     accumulates during S phase and G2, then targeted for
                     ubiquitin-mediated degradation; relative distribution to
                     the nucleus increases upon DNA replication stress; CLB3
                     has a paralog, CLB4, that arose from the whole genome
                     duplication"
                     /codon_start=1
                     /product="Clb3p"
                     /protein_id="NP_010126.1"
                     /db_xref="GI:6320046"
                     /db_xref="SGD:S000002314"
                     /db_xref="GeneID:851400"
                     /translation="MHHNSQSLSSGHIRSPEDENVAPIGNLKHRTGSLSHISSAHPRV
                     ALSDVTNIVATNSSNNSISKPKVAPIKERLDSAAIIEEERLDANSVAQRKEADHNDLL
                     TDREQEEPVEDDGESEEDEEEDQEPLLLQHYASDTLVWEHAFRTYYRTTLDPNDDDVY
                     DVVMVAELSNEIFEYMRKLEDLYKPNPYYMDKQPELRWSFRSTLIDWIVQVHEKFQLL
                     PETLYLCINIIDRYLCKEVVPVNKFQLVGAASLFIAAKYEEINCPTIKDFVYMSENCY
                     SRNDLLDAERTILNGLEFELGWPGPMSFLRRISKADDYEHDTRTLAKYLLESTIMDHR
                     LVSAQPSWLAAGAYFLSKIILGQNQWSLAHVYYSNYTQEQILPLATIILENCRYASKR
                     HNAIWRKYSSRRYLHSSQIVAKWIALAEHRVERSN"
     gene            <178334..>181039
                     /gene="MSH5"
                     /locus_tag="YDL154W"
                     /db_xref="GeneID:851401"
     mRNA            <178334..>181039
                     /gene="MSH5"
                     /locus_tag="YDL154W"
                     /product="MutS family protein MSH5"
                     /transcript_id="NM_001180214.1"
                     /db_xref="GI:296143214"
                     /db_xref="GeneID:851401"
     CDS             178334..181039
                     /gene="MSH5"
                     /locus_tag="YDL154W"
                     /note="Protein of the MutS family; forms a dimer with
                     Msh4p that facilitates crossovers between homologs during
                     meiosis; msh5-Y823H mutation confers tolerance to DNA
                     alkylating agents; homologs present in C. elegans and
                     humans"
                     /codon_start=1
                     /product="MutS family protein MSH5"
                     /protein_id="NP_010127.1"
                     /db_xref="GI:6320047"
                     /db_xref="SGD:S000002313"
                     /db_xref="GeneID:851401"
                     /translation="MSHEWLISASETMRSIGNGEGLRDKGAVVANNDGEFNEGDTNRE
                     EDSSTIFSFDFDEEIVMCIDFSGGKLGCSILDYHTKTLKAFDQDYVVNKTTISSHDLI
                     DDADMSSNDISLLLGLLIMEANPTVCLVPARLEDWIFDYIKTKCDEINCRLELQPIKR
                     FKKWDLLQSLQLRGHDNQTILNDILSNSKFTTTVTLGTVGCILANHEQLGEYNDSTAS
                     SNMVTGRLVQNAFEDVIHGIRYIDIRDRMVLDENTISALHIFPTAHKLGHDKMMRNGF
                     FSVFELFNQVSSDYARRILKSWLINPLTNKKRIETRYSIIRTLLDKQNAIIFSDLSQS
                     IKRCPDAFGFINQLRSGKSTLGTWSKVASFLEKGIAIFQLVSSLKLGSDEANILHDIK
                     NKVDISALKECLRKVETVIDFDTSRDTKTLTINTGVDNRLDECRNIYNHLEGILLDVA
                     RETQIFLLNTMPQEDCKTTKSLEKLVNAVYIPQLGYLVTISVLMEPLLDGIPNLQWEE
                     IFRSSENIYFKNGRVLELDETYGDIYGAISDFEIEILFSLQEQILRRKTQLTAYNILL
                     SELEILLSFAQVSAERNYAEPQLVEDECILEIINGRHALYETFLDNYIPNSTMIDGGL
                     FSELSWCEQNKGRIIVVTGANASGKSVYLTQNGLIVYLAQIGCFVPAERARIGIADKI
                     LTRIRTQETVYKTQSSFLLDSQQMAKSLSLATEKSLILIDEYGKGTDILDGPSLFGSI
                     MLNMSKSEKCPRIIACTHFHELFNENVLTENIKGIKHYCTDILISQKYNLLETAHVGE
                     DHESEGITFLFKVKEGISKQSFGIYCAKVCGLSRDIVERAEELSRMINRGDDVVQQCG
                     NLTEKEMREFQKNQEIVKKFLSWDLDLETTTTSENLRLKLKNFLR"
     gene            complement(<181186..>183018)
                     /gene="SAS10"
                     /locus_tag="YDL153C"
                     /gene_synonym="UTP3"
                     /db_xref="GeneID:851403"
     mRNA            complement(<181186..>183018)
                     /gene="SAS10"
                     /locus_tag="YDL153C"
                     /gene_synonym="UTP3"
                     /product="Sas10p"
                     /transcript_id="NM_001180213.1"
                     /db_xref="GI:296143215"
                     /db_xref="GeneID:851403"
     CDS             complement(181186..183018)
                     /gene="SAS10"
                     /locus_tag="YDL153C"
                     /gene_synonym="UTP3"
                     /note="Subunit of U3-containing Small Subunit (SSU)
                     processome complex; involved in production of 18S rRNA and
                     assembly of small ribosomal subunit; disrupts silencing
                     when overproduced; mutant has increased aneuploidy
                     tolerance; essential gene"
                     /codon_start=1
                     /product="Sas10p"
                     /protein_id="NP_010128.1"
                     /db_xref="GI:6320049"
                     /db_xref="SGD:S000002312"
                     /db_xref="GeneID:851403"
                     /translation="MVRKGSNRTKTSEVGDEINPYGLNEVDDFASKREKVLLGQSTFG
                     DSNKDDDHSLLEDEDEEEVLAMDEDDESIDEREDEEEEEEEELDGAAAYKKIFGRNLE
                     TDQLPEEDEENGMLDNENAWGSTKGEYYGADDLDDDEAAKEIEKEALRQQKKHLEELN
                     MNDYLDEEEEEEWVKSAKEFDMGEFKNSTKQADTKTSITDILNMDDEARDNYLRTMFP
                     EFAPLSKEFTELAPKFDELKKSEENEFNKLKLIALGSYLGTISCYYSILLHELHNNED
                     FTSMKGHPVMEKILTTKEIWRQASELPSSFDVNEGDGSESEETANIEAFNEKKLNELQ
                     NSEDSDAEDGGKQKQEIDEEERESDEEEEEEDVDIDDFEEYVAQSRLHSKPKTSSMPE
                     ADDFIESEIADVDAQDKKARRRTLRFYTSKIDQQENKKTDRFKGDDDIPYKERLFERQ
                     QRLLDEARKRGMHDNNGADLDDKDYGSEDEAVSRSINTQGENDYYQQVQRGKQDKKIS
                     RKEAHKNAVIAAREGKLAELAENVSGDGKRAINYQILKNKGLTPKRNKDNRNSRVKKR
                     KKYQKAQKKLKSVRAVYSGGQSGVYEGEKTGIKKGLTRSVKFKN"
     gene            <183343..>184611
                     /gene="RPC53"
                     /locus_tag="YDL150W"
                     /gene_synonym="RPC4"
                     /db_xref="GeneID:851404"
     mRNA            <183343..>184611
                     /gene="RPC53"
                     /locus_tag="YDL150W"
                     /gene_synonym="RPC4"
                     /product="Rpc53p"
                     /transcript_id="NM_001180210.1"
                     /db_xref="GI:296143216"
                     /db_xref="GeneID:851404"
     CDS             183343..184611
                     /gene="RPC53"
                     /locus_tag="YDL150W"
                     /gene_synonym="RPC4"
                     /note="RNA polymerase III subunit C53"
                     /codon_start=1
                     /product="Rpc53p"
                     /protein_id="NP_010131.1"
                     /db_xref="GI:6320050"
                     /db_xref="SGD:S000002309"
                     /db_xref="GeneID:851404"
                     /translation="MSSNKGNGRLPSLKDSSSNGGGSAKPSLKFKPKAVARKSKEERE
                     AAASKVKLEEESKRGNDKKHFNNKNKRVTGAGGQQRRMAKYLNNTHVISSGPLAAGNF
                     VSEKGDLRRGFIKSEGSGSSLVQKGLETIDNGAESSENEAEDDDNEGVASKSKKKFNM
                     GKEFEARNLIEDEDDGESEKSSDVDMDDEEWRSKRIEQLFPVRPVRVRHEDVETVKRE
                     IQEALSEKPTREPTPSVKTEPVGTGLQSYLEERERQVNEKLADLGLEKEFQSVDGKEA
                     AAELELLNADHQHILRKLKKMNNKPERFMVFQLPTRLPAFERPAVKEEKEDMETQASD
                     PSKKKKNIKKKDTKDALSTRELAGKVGSIRVHKSGKLSVKIGNVVMDIGKGAETTFLQ
                     DVIALSIADDASSAELLGRVDGKIVVTPQI"
     gene            <184925..>187918
                     /gene="ATG9"
                     /locus_tag="YDL149W"
                     /gene_synonym="APG9; AUT9; CVT6; CVT7"
                     /db_xref="GeneID:851406"
     mRNA            <184925..>187918
                     /gene="ATG9"
                     /locus_tag="YDL149W"
                     /gene_synonym="APG9; AUT9; CVT6; CVT7"
                     /product="Atg9p"
                     /transcript_id="NM_001180209.1"
                     /db_xref="GI:296143217"
                     /db_xref="GeneID:851406"
     CDS             184925..187918
                     /gene="ATG9"
                     /locus_tag="YDL149W"
                     /gene_synonym="APG9; AUT9; CVT6; CVT7"
                     /note="Transmembrane protein involved in forming Cvt and
                     autophagic vesicles; cycles between the phagophore
                     assembly site (PAS) and other cytosolic punctate
                     structures, not found in autophagosomes; may be involved
                     in membrane delivery to the PAS"
                     /codon_start=1
                     /product="Atg9p"
                     /protein_id="NP_010132.1"
                     /db_xref="GI:6320052"
                     /db_xref="SGD:S000002308"
                     /db_xref="GeneID:851406"
                     /translation="MERDEYQLPNSHGKNTFLSRIFGLQSDEVNPSLNSQEMSNFPLP
                     DIERGSSLLHSTNDSREDVDENDLRVPESDQGTSTEEEDEVDEEQVQAYAPQISDGLD
                     GDHQLNSVTSKENVLETEKSNLERLVEGSTDDSVPKVGQLSSEEEEDNEFINNDGFDD
                     DTPLFQKSKIHEFSSKKSNTIEDGKRPLFFRHILQNNRPQRDTQKLFTSSNAIHHDKD
                     KSANNGPRNINGNQKHGTKYFGSATQPRFTGSPLNNTNRFTKLFPLRKPNLLSNISVL
                     NNTPEDRINTLSVKERALWKWANVENLDIFLQDVYNYYLGNGFYCIILEKILNICTLL
                     FVVFVSTYMGHCVDYSKLPTSHRVSDIIIDKCYSNSITGFTKFFLWMFYFFVILKIVQ
                     LYFDVQKLSELQNFYKYLLNISDDELQTLPWQNVIQQLMYLKDQNAMTANVVEVKAKN
                     RIDAHDVANRIMRRENYLIALYNSDILNLSLPIPLFRTNVLTKTLEWNINLCVMGFVF
                     NESGFIKQSILKPSQREFTREELQKRFMLAGFLNIILAPFLVTYFVLLYFFRYFNEYK
                     TSPGSIGARQYTPIAEWKFREYNELYHIFKKRISLSTTLANKYVDQFPKEKTNLFLKF
                     VSFICGSFVAILAFLTVFDPENFLNFEITSDRSVIFYITILGAIWSVSRNTITQEYHV
                     FDPEETLKELYEYTHYLPKEWEGRYHKEEIKLEFCKLYNLRIVILLRELTSLMITPFV
                     LWFSLPSSAGRIVDFFRENSEYVDGLGYVCKYAMFNMKNIDGEDTHSMDEDSLTKKIA
                     VNGSHTLNSKRRSKFTAEDHSDKDLANNKMLQSYVYFMDDYSNSENLTGKYQLPAKKG
                     YPNNEGDSFLNNKYSWRKQFQPGQKPELFRIGKHALGPGHNISPAIYSTRNPGKNWDN
                     NNNGDDIKNGTNNATAKNDDNNGNNDHEYVLTESFLDSGAFPNHDVIDHNKMLNSNYN
                     GNGILNKGGVLGLVKEYYKKSDVGR"
     gene            complement(<188154..>190586)
                     /gene="NOP14"
                     /locus_tag="YDL148C"
                     /gene_synonym="UTP2"
                     /db_xref="GeneID:851407"
     mRNA            complement(<188154..>190586)
                     /gene="NOP14"
                     /locus_tag="YDL148C"
                     /gene_synonym="UTP2"
                     /product="Nop14p"
                     /transcript_id="NM_001180208.1"
                     /db_xref="GI:296143218"
                     /db_xref="GeneID:851407"
     CDS             complement(188154..190586)
                     /gene="NOP14"
                     /locus_tag="YDL148C"
                     /gene_synonym="UTP2"
                     /note="Nucleolar protein; forms a complex with Noc4p that
                     mediates maturation and nuclear export of 40S ribosomal
                     subunits; also present in the small subunit processome
                     complex, which is required for processing of pre-18S rRNA"
                     /codon_start=1
                     /product="Nop14p"
                     /protein_id="NP_010133.1"
                     /db_xref="GI:6320053"
                     /db_xref="SGD:S000002307"
                     /db_xref="GeneID:851407"
                     /translation="MAGSQLKNLKAALKARGLTGQTNVKSKNKKNSKRQAKEYDREEK
                     KKAIAEIREEFNPFEIKAARNKRRDGLPSKTADRIAVGKPGISKQIGEEQRKRAFEAR
                     KMMKNKRGGVIDKRFGERDKLLTEEEKMLERFTRERQSQSKRNANLFNLEDDEDDGDM
                     FGDGLTHLGQSLSLEDELANDEEDFLASKRFNEDDAELQQPQRKKTKAEVMKEVIAKS
                     KFYKQERQKAQGIMEDQIDNLDDNFEDVMSELMMTQPKKNPMEPKTDLDKEYDIKVKE
                     LQLDKRAAPSDRTKTEEEKNAEAEEKKRELEQQRLDRMNGMIELEEGEERGVEDLDDG
                     FWENEEDYEDDNDGIADSDDDIKFEDQGRDEGFSQILKKKNISISCPRTHDALLDQVK
                     KLDLDDHPKIVKNIIKAYQPKLAEGNKEKLGKFTAVLLRHIIFLSNQNYLKNVQSFKR
                     TQNALISILKSLSEKYNRELSEECRDYINEMQARYKKNHFDALSNGDLVFFSIIGILF
                     STSDQYHLVITPALILMSQFLEQIKFNSLKRIAFGAVLVRIVSQYQRISKRYIPEVVY
                     FFQKILLTFIVEKENQEKPLDFENIRLDSYELGLPLDVDFTKKRSTIIPLHTLSTMDT
                     EAHPVDQCVSVLLNVMESLDATISTVWKSLPAFNEIILPIQQLLSAYTSKYSDFEKPR
                     NILNKVEKLTKFTEHIPLALQNHKPVSIPTHAPKYEENFNPDKKSYDPDRTRSEINKM
                     KAQLKKERKFTMKEIRKDAKFEARQRIEEKNKESSDYHAKMAHIVNTINTEEGAEKNK
                     YERERKLRGGKK"
     gene            <190924..>192261
                     /gene="RPN5"
                     /locus_tag="YDL147W"
                     /gene_synonym="NAS5"
                     /db_xref="GeneID:851408"
     mRNA            <190924..>192261
                     /gene="RPN5"
                     /locus_tag="YDL147W"
                     /gene_synonym="NAS5"
                     /product="proteasome regulatory particle lid subunit RPN5"
                     /transcript_id="NM_001180207.1"
                     /db_xref="GI:296143219"
                     /db_xref="GeneID:851408"
     CDS             190924..192261
                     /gene="RPN5"
                     /locus_tag="YDL147W"
                     /gene_synonym="NAS5"
                     /note="Subunit of the CSN and 26S proteasome lid
                     complexes; similar to mammalian p55 subunit and to another
                     S. cerevisiae regulatory subunit, Rpn7p; Rpn5p is an
                     essential protein; the COP9 signalosome is also known as
                     the CSN"
                     /codon_start=1
                     /product="proteasome regulatory particle lid subunit RPN5"
                     /protein_id="NP_010134.1"
                     /db_xref="GI:6320054"
                     /db_xref="SGD:S000002306"
                     /db_xref="GeneID:851408"
                     /translation="MSRDAPIKADKDYSQILKEEFPKIDSLAQNDCNSALDQLLVLEK
                     KTRQASDLASSKEVLAKIVDLLASRNKWDDLNEQLTLLSKKHGQLKLSIQYMIQKVME
                     YLKSSKSLDLNTRISVIETIRVVTENKIFVEVERARVTKDLVEIKKEEGKIDEAADIL
                     CELQVETYGSMEMSEKIQFILEQMELSILKGDYSQATVLSRKILKKTFKNPKYESLKL
                     EYYNLLVKISLHKREYLEVAQYLQEIYQTDAIKSDEAKWKPVLSHIVYFLVLSPYGNL
                     QNDLIHKIQNDNNLKKLESQESLVKLFTTNELMRWPIVQKTYEPVLNEDDLAFGGEAN
                     KHHWEDLQKRVIEHNLRVISEYYSRITLLRLNELLDLTESQTETYISDLVNQGIIYAK
                     VNRPAKIVNFEKPKNSSQLLNEWSHNVDELLEHIETIGHLITKEEIMHGLQAK"
     gene            <192750..>194225
                     /gene="LDB17"
                     /locus_tag="YDL146W"
                     /db_xref="GeneID:851409"
     mRNA            <192750..>194225
                     /gene="LDB17"
                     /locus_tag="YDL146W"
                     /product="Ldb17p"
                     /transcript_id="NM_001180206.1"
                     /db_xref="GI:296143220"
                     /db_xref="GeneID:851409"
     CDS             192750..194225
                     /gene="LDB17"
                     /locus_tag="YDL146W"
                     /note="Protein involved in the regulation of endocytosis;
                     transiently recruited to actin cortical patches in a
                     SLA1-dependent manner after late coat component assembly;
                     GFP-fusion protein localizes to the periphery, cytoplasm,
                     bud, and bud neck"
                     /codon_start=1
                     /product="Ldb17p"
                     /protein_id="NP_010135.1"
                     /db_xref="GI:6320055"
                     /db_xref="SGD:S000002305"
                     /db_xref="GeneID:851409"
                     /translation="MILDPLSPNIENHTQDEIIEFWEKTESIANIPKENLDESHVNSS
                     LVAYLKFATDSYKVFINTDRDLYRMSLILLESSLFEFKKEFCLSKLQSLLNIDLLEMN
                     MKFIIVYILLCEAKKNVYSLEIMLKFQGFTVFYNTLYTQFAYLSKYGKERTVASKHQY
                     NSNNSSTGTSLDSLDRSLTDIDLGIIDEMKQISTVLMDLLFQIMKYCKCVIANLQIVD
                     DFFVYYMMESMRSDTMDDMFNNAEFKLLLALNEQYMMFAKEYDIENKVYKYLINGSVS
                     RCFTELLLLKFNRASDPPLQIMMCKIIYLILTPRGDYSPMNFFYTNDLRVLIDVLIRE
                     LQNISEDEEVLRNTLLRVLIPLLKNTQLSKTHYRKDDLNKLLNYLSTLDNICVDSPAL
                     HEHQVTVALSRKCLQQIPWLETPSTPSDGGSSVSSNNTSRNSSIVALGTPDNQNILAR
                     KGHLYSNRELDVSAESLTKRKAKAPPPPPPPPPSRKCGTPK"
     gene            complement(<194571..>198176)
                     /gene="COP1"
                     /locus_tag="YDL145C"
                     /gene_synonym="RET1; SEC33; SOO1"
                     /db_xref="GeneID:851410"
     mRNA            complement(<194571..>198176)
                     /gene="COP1"
                     /locus_tag="YDL145C"
                     /gene_synonym="RET1; SEC33; SOO1"
                     /product="Cop1p"
                     /transcript_id="NM_001180205.1"
                     /db_xref="GI:296143221"
                     /db_xref="GeneID:851410"
     CDS             complement(194571..198176)
                     /gene="COP1"
                     /locus_tag="YDL145C"
                     /gene_synonym="RET1; SEC33; SOO1"
                     /note="Alpha subunit of COPI vesicle coatomer complex;
                     complex surrounds transport vesicles in the early
                     secretory pathway"
                     /codon_start=1
                     /product="Cop1p"
                     /protein_id="NP_010136.1"
                     /db_xref="GI:6320056"
                     /db_xref="SGD:S000002304"
                     /db_xref="GeneID:851410"
                     /translation="MKMLTKFESKSTRAKGIAFHPSRPWVLVALFSSTIQLWDYRMGT
                     LLHRFEDHEGPVRGLDFHPTQPIFVSAGDDYTIKVWSLDTNKCLYTLTGHLDYVRTVF
                     FHRELPWIISASDDQTIRIWNWQNRKEIACLTGHNHFVMCAQFHPTDDLIVSASLDET
                     IRIWDISGLRKRHSAPGTSSFEEQMSAQQNLLDGSLGDCVVKFILEGHTRGVNWASFH
                     PTLPLIVSGSDDRQVKLWRMSATKAWEVDTCRGHTNNVDSVIFHPHQNLIISVGEDKT
                     LRVWDLDKRTPVKQFKRENDRFWLIAAHPHINLFGAAHDSGIMVFKLDRERPCSFIHQ
                     NQLFFVNAEKQIQSFNFQKRVASLPYASLKGIGQPWDAFRSISYNPSQHSVLVNEANG
                     KFALVILPKQPVGAVEPTSVTQDTGNFATFVGRNRFVVYNKNTESVEVRSLENKVTRN
                     IKVEETVRTIVAAGPGSVLVIHPREVILYDVQQGKKVSQLAVKNVKYVSWSLDGQYVA
                     LMSKHTITLATKKLELINSMHETIRIKSAAWDETGVLIYSTLNHIRYSLLNGDRGIIK
                     TLEKTLYITKVQGKLVYCLNREGEIEILTIDPTEYRFKKALVNKNFPEVLRLIKDSNL
                     VGQNIISYLQKSGYPEIALQFVQDPHIRFDLALEYGNLDVALDEAKKLNDSSTWERLI
                     QEALAQGNASLAEMIYQTQHSFDKLSFLYLVTGDVNKLSKMQNIAQTREDFGSMLLNT
                     FYNNSTKERSSIFAEGGSLPLAYAVAKANGDEAAASAFLEQAEVDEQDVTLPDQMDAS
                     NFVQRPVISKPLEKWPLKEAELSYFEKAVLGQIDDLTIDDETPAVNTTQEQEEPLGEE
                     NFNDEDIGEDEGAWDLGDEDLDVGEELPEEVEQGEITSPAQEVETAIWIKNSKLPAVL
                     VAAGAFDAAVQALSKQVGVVKLEPLKKYFTNIYEGCRTYIPSTPCELPAQLGYVRAYD
                     DTVSEDQILPYVPGLDVVNEKMNEGYKNFKLNKPDIAIECFREAIYRITLLMVDDAED
                     EKLAHKILETAREYILGLSIELERRSLKEGNTVRMLELAAYFTKAKLSPIHRTNALQV
                     AMSQHFKHKNFLQASYFAGEFLKIISSGPRAEQARKIKNKADSMASDAIPIDFDPYAK
                     FDICAATYKPIYEDTPSVSDPLTGSKYVITEKDKIDRIAMISKIGAPASGLRIRV"
     gene            complement(<198662..>199732)
                     /locus_tag="YDL144C"
                     /db_xref="GeneID:851411"
     mRNA            complement(<198662..>199732)
                     /locus_tag="YDL144C"
                     /product="hypothetical protein"
                     /transcript_id="NM_001180204.1"
                     /db_xref="GI:296143222"
                     /db_xref="GeneID:851411"
     CDS             complement(198662..199732)
                     /locus_tag="YDL144C"
                     /note="hypothetical protein; green fluorescent protein
                     (GFP)-fusion protein localizes to the cytoplasm and
                     nucleus; YDL144C is not an essential gene; protein
                     abundance increases in response to DNA replication stress"
                     /codon_start=1
                     /product="hypothetical protein"
                     /protein_id="NP_010137.2"
                     /db_xref="GI:37362628"
                     /db_xref="SGD:S000002303"
                     /db_xref="GeneID:851411"
                     /translation="MSRILVIGAGGVGVITALSLWLKKESDVSLVVRSDYDRVLKHGY
                     TIESCDYGRLEGWRPHHIYSSVEDAASAADNQGYNYIVVTTKNIIDGPVNSRVSNIIR
                     PVLEKNKELHGPQLTTHILLVQNGIDIEKEIWAEFPREQYRYTVLSGIQLIGSTKIGS
                     GHISQVGQDHLSCGAFDPQDAAAIQAANDFVRMYSNEGQNFVEFDPRVRYSRWKKLLY
                     NAAINTSTALVGLDVPRCLEFGVNKKSTEIEVFHPAMREIIAIAASEGIIIEEEFITM
                     FTEITRKKVFKPSMCVDCEKGQLMELEVILGNPIRIAKRNGVATPTLSILYNLLVLVQ
                     AKLKERKGLLKFDEKTATLVDE"
     gene            <199996..>201582
                     /gene="CCT4"
                     /locus_tag="YDL143W"
                     /gene_synonym="ANC2; TCP4"
                     /db_xref="GeneID:851412"
     mRNA            <199996..>201582
                     /gene="CCT4"
                     /locus_tag="YDL143W"
                     /gene_synonym="ANC2; TCP4"
                     /product="Cct4p"
                     /transcript_id="NM_001180203.1"
                     /db_xref="GI:296143223"
                     /db_xref="GeneID:851412"
     CDS             199996..201582
                     /gene="CCT4"
                     /locus_tag="YDL143W"
                     /gene_synonym="ANC2; TCP4"
                     /note="Subunit of the cytosolic chaperonin Cct ring
                     complex; related to Tcp1p, required for the assembly of
                     actin and tubulins in vivo"
                     /codon_start=1
                     /product="Cct4p"
                     /protein_id="NP_010138.1"
                     /db_xref="GI:6320058"
                     /db_xref="SGD:S000002302"
                     /db_xref="GeneID:851412"
                     /translation="MSAKVPSNATFKNKEKPQEVRKANIIAARSVADAIRTSLGPKGM
                     DKMIKTSRGEIIISNDGHTILKQMAILHPVARMLVEVSAAQDSEAGDGTTSVVILTGA
                     LLGAAERLLNKGIHPTIIADSFQSAAKRSVDILLEMCHKVSLSDREQLVRAASTSLSS
                     KIVSQYSSFLAPLAVDSVLKISDENSKNVDLNDIRLVKKVGGTIDDTEMIDGVVLTQT
                     AIKSAGGPTRKEKAKIGLIQFQISPPKPDTENNIIVNDYRQMDKILKEERAYLLNICK
                     KIKKAKCNVLLIQKSILRDAVNDLALHFLSKLNIMVVKDIEREEIEFLSKGLGCKPIA
                     DIELFTEDRLGSADLVEEIDSDGSKIVRVTGIRNNNARPTVSVVIRGANNMIIDETER
                     SLHDALCVIRCLVKERGLIAGGGAPEIEISRRLSKEARSMEGVQAFIWQEFASALEVI
                     PTTLAENAGLNSIKVVTELRSKHENGELNDGISVRRSGTTNTYEEHILQPVLVSTSAI
                     TLASECVKSILRIDDIAFSR"
     gene            complement(<201719..>202570)
                     /gene="CRD1"
                     /locus_tag="YDL142C"
                     /gene_synonym="CLS1"
                     /db_xref="GeneID:851413"
     mRNA            complement(<201719..>202570)
                     /gene="CRD1"
                     /locus_tag="YDL142C"
                     /gene_synonym="CLS1"
                     /product="cardiolipin synthase"
                     /transcript_id="NM_001180202.1"
                     /db_xref="GI:296143224"
                     /db_xref="GeneID:851413"
     CDS             complement(201719..202570)
                     /gene="CRD1"
                     /locus_tag="YDL142C"
                     /gene_synonym="CLS1"
                     /EC_number="2.7.8.-"
                     /note="Cardiolipin synthase; produces cardiolipin, which
                     is a phospholipid of the mitochondrial inner membrane that
                     is required for normal mitochondrial membrane potential
                     and function; required to maintain tubular mitochondrial
                     morphology and functions in mitochondrial fusion; also
                     required for normal vacuolar ion homeostasis"
                     /codon_start=1
                     /product="cardiolipin synthase"
                     /protein_id="NP_010139.1"
                     /db_xref="GI:6320059"
                     /db_xref="SGD:S000002301"
                     /db_xref="GeneID:851413"
                     /translation="MIQMVPIYSCSALLRRTIPKRPFYHVLSGLTVRFKVNPQLNYNL
                     FRDLTRREYATNPSKTPHIKSKLLNIPNILTLSRIGCTPFIGLFIITNNLTPALGLFA
                     FSSITDFMDGYIARKYGLKTIAGTILDPLADKLLMITTTLALSVPSGPQIIPVSIAAI
                     ILGRDVLLAISALFIRYSTLKLKYPGRVAWNSYWDIVRYPSAEVRPSQLSKWNTFFQM
                     VYLGSGVLLLLYEKEEGCEKTEEDFEDRKQDFQKAFSYLGYVTATTTIMSGVSYALKR
                     NAFKLLK"
     gene            <203039..>205111
                     /gene="BPL1"
                     /locus_tag="YDL141W"
                     /gene_synonym="ACC2"
                     /db_xref="GeneID:851414"
     mRNA            <203039..>205111
                     /gene="BPL1"
                     /locus_tag="YDL141W"
                     /gene_synonym="ACC2"
                     /product="biotin--[acetyl-CoA-carboxylase] ligase BPL1"
                     /transcript_id="NM_001180201.1"
                     /db_xref="GI:296143225"
                     /db_xref="GeneID:851414"
     CDS             203039..205111
                     /gene="BPL1"
                     /locus_tag="YDL141W"
                     /gene_synonym="ACC2"
                     /EC_number="6.3.4.11"
                     /EC_number="6.3.4.10"
                     /EC_number="6.3.4.9"
                     /EC_number="6.3.4.15"
                     /EC_number="6.3.4.-"
                     /note="Biotin:apoprotein ligase; covalently modifies
                     proteins with the addition of biotin, required for
                     acetyl-CoA carboxylase (Acc1p) holoenzyme formation"
                     /codon_start=1
                     /product="biotin--[acetyl-CoA-carboxylase] ligase BPL1"
                     /protein_id="NP_010140.1"
                     /db_xref="GI:6320060"
                     /db_xref="SGD:S000002300"
                     /db_xref="GeneID:851414"
                     /translation="MNVLVYNGPGTTPGSVKHAVESLRDFLEPYYAVSTVNVKVLQTE
                     PWMSKTSAVVFPGGADLPYVQACQPIISRLKHFVSKQGGVFIGFCAGGYFGTSRVEFA
                     QGDPTMEVSGSRDLRFFPGTSRGPAYNGFQYNSEAGARAVKLNLPDGSQFSTYFNGGA
                     VFVDADKFDNVEILATYAEHPDVPSSDSGKGQSENPAAVVLCTVGRGKVLLTGPHPEF
                     NVRFMRKSTDKHFLETVVENLKAQEIMRLKFMRTVLTKTGLNCNNDFNYVRAPNLTPL
                     FMASAPNKRNYLQEMENNLAHHGMHANNVELCSELNAETDSFQFYRGYRASYDAASSS
                     LLHKEPDEVPKTVIFPGVDEDIPPFQYTPNFDMKEYFKYLNVQNTIGSLLLYGEVVTS
                     TSTILNNNKSLLSSIPESTLLHVGTIQVSGRGRGGNTWINPKGVCASTAVVTMPLQSP
                     VTNRNISVVFVQYLSMLAYCKAILSYAPGFSDIPVRIKWPNDLYALSPTYYKRKNLKL
                     VNTGFEHTKLPLGDIEPAYLKISGLLVNTHFINNKYCLLLGCGINLTSDGPTTSLQTW
                     IDILNEERQQLHLDLLPAIKAEKLQALYMNNLEVILKQFINYGAAEILPSYYELWLHS
                     NQIVTLPDHGNTQAMITGITEDYGLLIAKELVSGSSTQFTGNVYNLQPDGNTFDIFKS
                     LIAKKVQS"
     gene            complement(<205360..>210561)
                     /gene="RPO21"
                     /locus_tag="YDL140C"
                     /gene_synonym="RPB1; RPB220; SUA8"
                     /db_xref="GeneID:851415"
     mRNA            complement(<205360..>210561)
                     /gene="RPO21"
                     /locus_tag="YDL140C"
                     /gene_synonym="RPB1; RPB220; SUA8"
                     /product="DNA-directed RNA polymerase II core subunit
                     RPO21"
                     /transcript_id="NM_001180200.1"
                     /db_xref="GI:296143226"
                     /db_xref="GeneID:851415"
     CDS             complement(205360..210561)
                     /gene="RPO21"
                     /locus_tag="YDL140C"
                     /gene_synonym="RPB1; RPB220; SUA8"
                     /EC_number="2.7.7.6"
                     /note="RNA polymerase II largest subunit B220; part of
                     central core; phosphorylation of C-terminal heptapeptide
                     repeat domain regulates association with transcription and
                     splicing factors; similar to bacterial beta-prime"
                     /codon_start=1
                     /product="DNA-directed RNA polymerase II core subunit
                     RPO21"
                     /protein_id="NP_010141.1"
                     /db_xref="GI:6320061"
                     /db_xref="SGD:S000002299"
                     /db_xref="GeneID:851415"
                     /translation="MVGQQYSSAPLRTVKEVQFGLFSPEEVRAISVAKIRFPETMDET
                     QTRAKIGGLNDPRLGSIDRNLKCQTCQEGMNECPGHFGHIDLAKPVFHVGFIAKIKKV
                     CECVCMHCGKLLLDEHNELMRQALAIKDSKKRFAAIWTLCKTKMVCETDVPSEDDPTQ
                     LVSRGGCGNTQPTIRKDGLKLVGSWKKDRATGDADEPELRVLSTEEILNIFKHISVKD
                     FTSLGFNEVFSRPEWMILTCLPVPPPPVRPSISFNESQRGEDDLTFKLADILKANISL
                     ETLEHNGAPHHAIEEAESLLQFHVATYMDNDIAGQPQALQKSGRPVKSIRARLKGKEG
                     RIRGNLMGKRVDFSARTVISGDPNLELDQVGVPKSIAKTLTYPEVVTPYNIDRLTQLV
                     RNGPNEHPGAKYVIRDSGDRIDLRYSKRAGDIQLQYGWKVERHIMDNDPVLFNRQPSL
                     HKMSMMAHRVKVIPYSTFRLNLSVTSPYNADFDGDEMNLHVPQSEETRAELSQLCAVP
                     LQIVSPQSNKPCMGIVQDTLCGIRKLTLRDTFIELDQVLNMLYWVPDWDGVIPTPAII
                     KPKPLWSGKQILSVAIPNGIHLQRFDEGTTLLSPKDNGMLIIDGQIIFGVVEKKTVGS
                     SNGGLIHVVTREKGPQVCAKLFGNIQKVVNFWLLHNGFSTGIGDTIADGPTMREITET
                     IAEAKKKVLDVTKEAQANLLTAKHGMTLRESFEDNVVRFLNEARDKAGRLAEVNLKDL
                     NNVKQMVMAGSKGSFINIAQMSACVGQQSVEGKRIAFGFVDRTLPHFSKDDYSPESKG
                     FVENSYLRGLTPQEFFFHAMGGREGLIDTAVKTAETGYIQRRLVKALEDIMVHYDNTT
                     RNSLGNVIQFIYGEDGMDAAHIEKQSLDTIGGSDAAFEKRYRVDLLNTDHTLDPSLLE
                     SGSEILGDLKLQVLLDEEYKQLVKDRKFLREVFVDGEANWPLPVNIRRIIQNAQQTFH
                     IDHTKPSDLTIKDIVLGVKDLQENLLVLRGKNEIIQNAQRDAVTLFCCLLRSRLATRR
                     VLQEYRLTKQAFDWVLSNIEAQFLRSVVHPGEMVGVLAAQSIGEPATQMTLNTFHFAG
                     VASKKVTSGVPRLKEILNVAKNMKTPSLTVYLEPGHAADQEQAKLIRSAIEHTTLKSV
                     TIASEIYYDPDPRSTVIPEDEEIIQLHFSLLDEEAEQSFDQQSPWLLRLELDRAAMND
                     KDLTMGQVGERIKQTFKNDLFVIWSEDNDEKLIIRCRVVRPKSLDAETEAEEDHMLKK
                     IENTMLENITLRGVENIERVVMMKYDRKVPSPTGEYVKEPEWVLETDGVNLSEVMTVP
                     GIDPTRIYTNSFIDIMEVLGIEAGRAALYKEVYNVIASDGSYVNYRHMALLVDVMTTQ
                     GGLTSVTRHGFNRSNTGALMRCSFEETVEILFEAGASAELDDCRGVSENVILGQMAPI
                     GTGAFDVMIDEESLVKYMPEQKITEIEDGQDGGVTPYSNESGLVNADLDVKDELMFSP
                     LVDSGSNDAMAGGFTAYGGADYGEATSPFGAYGEAPTSPGFGVSSPGFSPTSPTYSPT
                     SPAYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSP
                     SYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPAYSPTSPSY
                     SPTSPSYSPTSPSYSPTSPSYSPTSPNYSPTSPSYSPTSPGYSPGSPAYSPKQDEQKH
                     NENENSR"
     gene            complement(<211375..>212046)
                     /gene="SCM3"
                     /locus_tag="YDL139C"
                     /db_xref="GeneID:851416"
     mRNA            complement(<211375..>212046)
                     /gene="SCM3"
                     /locus_tag="YDL139C"
                     /product="Scm3p"
                     /transcript_id="NM_001180199.1"
                     /db_xref="GI:296143227"
                     /db_xref="GeneID:851416"
     CDS             complement(211375..212046)
                     /gene="SCM3"
                     /locus_tag="YDL139C"
                     /note="Nonhistone component of centromeric chromatin;
                     binds to histone H3 variant, Cse4p, and recruits it to
                     centromeres; involved in the assembly and maintenance of
                     Cse4-H4 at centromeres; required for kinetochore assembly
                     and G2/M progression; may protect Cse4p from
                     ubiquitylation; homolog of mammalian HJURP"
                     /codon_start=1
                     /product="Scm3p"
                     /protein_id="NP_010142.2"
                     /db_xref="GI:37362629"
                     /db_xref="SGD:S000002298"
                     /db_xref="GeneID:851416"
                     /translation="MKTNKKISKRRSLKNLHGALKGLLKESGKKSESKIRKHSDCNPV
                     HRVYPPNIEKRKTKKDDGISRPIAERNGHVYIMSKENHIIPKLTDDEVMERHKLADEN
                     MRKVWSNIISKYESIEEQGDLVDLKTGEIVEDNGHIKTLTANNSTKDKRTKYTSVLRD
                     IIDISDEEDGDKNDEYTLWANDSEASDSEVDADNDTEEEKDEKLIDADFKKYEAKLSK
                     RILRD"
     rep_origin      212420..212668
                     /note="ARS409;
                     Autonomously Replicating Sequence"
                     /db_xref="SGD:S000118430"
     gene            <213351..>215642
                     /gene="RGT2"
                     /locus_tag="YDL138W"
                     /db_xref="GeneID:851417"
     mRNA            <213351..>215642
                     /gene="RGT2"
                     /locus_tag="YDL138W"
                     /product="Rgt2p"
                     /transcript_id="NM_001180198.1"
                     /db_xref="GI:296143228"
                     /db_xref="GeneID:851417"
     CDS             213351..215642
                     /gene="RGT2"
                     /locus_tag="YDL138W"
                     /note="Plasma membrane high glucose sensor that regulates
                     glucose transport; contains 12 predicted transmembrane
                     segments and a long C-terminal tail required for induction
                     of hexose transporters; RGT2 has a paralog, SNF3, that
                     arose from the whole genome duplication"
                     /codon_start=1
                     /product="Rgt2p"
                     /protein_id="NP_010143.1"
                     /db_xref="GI:6320063"
                     /db_xref="SGD:S000002297"
                     /db_xref="GeneID:851417"
                     /translation="MNDSQNCLRQREENSHLNPGNDFGHHQGAECTINHNNMPHRNAY
                     TESTNDTEAKSIVMCDDPNAYQISYTNNEPAGDGAIETTSILLSQPLPLRSNVMSVLV
                     GIFVAVGGFLFGYDTGLINSITDMPYVKTYIAPNHSYFTTSQIAILVSFLSLGTFFGA
                     LIAPYISDSYGRKPTIMFSTAVIFSIGNSLQVASGGLVLLIVGRVISGIGIGIISAVV
                     PLYQAEAAQKNLRGAIISSYQWAITIGLLVSSAVSQGTHSKNGPSSYRIPIGLQYVWS
                     SILAVGMIFLPESPRYYVLKDELNKAAKSLSFLRGLPIEDPRLLEELVEIKATYDYEA
                     SFGPSTLLDCFKTSENRPKQILRIFTGIAIQAFQQASGINFIFYYGVNFFNNTGVDNS
                     YLVSFISYAVNVAFSIPGMYLVDRIGRRPVLLAGGVIMAIANLVIAIVGVSEGKTVVA
                     SKIMIAFICLFIAAFSATWGGVVWVVSAELYPLGVRSKCTAICAAANWLVNFTCALIT
                     PYIVDVGSHTSSMGPKIFFIWGGLNVVAVIVVYFAVYETRGLTLEEIDELFRKAPNSV
                     ISSKWNKKIRKRCLAFPISQQIEMKTNIKNAGKLDNNNSPIVQDDSHNIIDVDGFLEN
                     QIQSNDHMIAADKGSGSLVNIIDTAPLTSTEFKPVEHPPVNYVDLGNGLGLNTYNRGP
                     PSIISDSTDEFYEENDSSYYNNNTERNGANSVNTYMAQLINSSSTTSNDTSFSPSHNS
                     NARTSSNWTSDLASKHSQYTSPQ"
     gene            <216529..>217074
                     /gene="ARF2"
                     /locus_tag="YDL137W"
                     /db_xref="GeneID:851418"
     mRNA            <216529..>217074
                     /gene="ARF2"
                     /locus_tag="YDL137W"
                     /product="Arf family GTPase ARF2"
                     /transcript_id="NM_001180197.1"
                     /db_xref="GI:296143229"
                     /db_xref="GeneID:851418"
     CDS             216529..217074
                     /gene="ARF2"
                     /locus_tag="YDL137W"
                     /note="ADP-ribosylation factor; GTPase of the Ras
                     superfamily involved in regulation of coated formation
                     vesicles in intracellular trafficking within the Golgi;
                     ARF2 has a paralog, ARF1, that arose from the whole genome
                     duplication"
                     /codon_start=1
                     /product="Arf family GTPase ARF2"
                     /protein_id="NP_010144.1"
                     /db_xref="GI:6320064"
                     /db_xref="SGD:S000002296"
                     /db_xref="GeneID:851418"
                     /translation="MGLYASKLFSNLFGNKEMRILMVGLDGAGKTTVLYKLKLGEVIT
                     TIPTIGFNVETVQYKNISFTVWDVGGQDRIRSLWRHYYRNTEGVIFVIDSNDRSRIGE
                     AREVMQRMLNEDELRNAVWLVFANKQDLPEAMSAAEITEKLGLHSIRNRPWFIQSTCA
                     TSGEGLYEGLEWLSNNLKNQS"
     gene            <217600..>218367
                     /gene="RPL35B"
                     /locus_tag="YDL136W"
                     /gene_synonym="SOS2"
                     /db_xref="GeneID:851419"
     mRNA            join(<217600..217602,218008..>218367)
                     /gene="RPL35B"
                     /locus_tag="YDL136W"
                     /gene_synonym="SOS2"
                     /product="ribosomal 60S subunit protein L35B"
                     /transcript_id="NM_001180251.2"
                     /db_xref="GI:330443501"
                     /db_xref="GeneID:851419"
     CDS             join(217600..217602,218008..218367)
                     /gene="RPL35B"
                     /locus_tag="YDL136W"
                     /gene_synonym="SOS2"
                     /note="Ribosomal 60S subunit protein L35B; homologous to
                     mammalian ribosomal protein L35 and bacterial L29; RPL35B
                     has a paralog, RPL35A, that arose from the whole genome
                     duplication"
                     /codon_start=1
                     /product="ribosomal 60S subunit protein L35B"
                     /protein_id="NP_010090.1"
                     /db_xref="GI:6320010"
                     /db_xref="SGD:S000002295"
                     /db_xref="GeneID:851419"
                     /translation="MAGVKAYELRTKSKEQLASQLVDLKKELAELKVQKLSRPSLPKI
                     KTVRKSIACVLTVINEQQREAVRQLYKGKKYQPKDLRAKKTRALRRALTKFEASQVTE
                     KQRKKQIAFPQRKYAIKA"
     gene            complement(<218680..>219288)
                     /gene="RDI1"
                     /locus_tag="YDL135C"
                     /db_xref="GeneID:851420"
     mRNA            complement(<218680..>219288)
                     /gene="RDI1"
                     /locus_tag="YDL135C"
                     /product="Rdi1p"
                     /transcript_id="NM_001180195.1"
                     /db_xref="GI:296143231"
                     /db_xref="GeneID:851420"
     CDS             complement(218680..219288)
                     /gene="RDI1"
                     /locus_tag="YDL135C"
                     /note="Rho GDP dissociation inhibitor; involved in the
                     localization and regulation of Cdc42p and Rho1p; protein
                     abundance increases in response to DNA replication stress"
                     /codon_start=1
                     /product="Rdi1p"
                     /protein_id="NP_010146.1"
                     /db_xref="GI:6320066"
                     /db_xref="SGD:S000002294"
                     /db_xref="GeneID:851420"
                     /translation="MAEESTDFSQFEEERNNDQYKVSAKKTVDEYKNLDAEDESLAKW
                     KESLGLSSDVLPLEFPGDKRKVVVQKIQLLVNTEPNPITFDLTNEKTIKELASKRYKI
                     KENSIYKLKIVFKVQHEIITGLRYVQYIKKAGIAVDKIDDHLGSYAPNTKTKPFYEVE
                     LPESEAPSGFLARGNYSAVSKFIDDDKTNHLTLNWGVEIVKK"
     gene            complement(<219662..>220771)
                     /gene="PPH21"
                     /locus_tag="YDL134C"
                     /db_xref="GeneID:851421"
     mRNA            complement(<219662..>220771)
                     /gene="PPH21"
                     /locus_tag="YDL134C"
                     /product="phosphoprotein phosphatase 2A catalytic subunit
                     PPH21"
                     /transcript_id="NM_001180193.1"
                     /db_xref="GI:296143232"
                     /db_xref="GeneID:851421"
     CDS             complement(219662..220771)
                     /gene="PPH21"
                     /locus_tag="YDL134C"
                     /EC_number="3.1.3.16"
                     /note="Catalytic subunit of protein phosphatase 2A (PP2A);
                     functionally redundant with Pph22p; methylated at C
                     terminus; forms alternate complexes with several
                     regulatory subunits; involved in signal transduction and
                     regulation of mitosis; forms nuclear foci upon DNA
                     replication stress; PPH21 has a paralog, PPH22, that arose
                     from the whole genome duplication"
                     /codon_start=1
                     /product="phosphoprotein phosphatase 2A catalytic subunit
                     PPH21"
                     /protein_id="NP_010147.1"
                     /db_xref="GI:6320067"
                     /db_xref="SGD:S000002292"
                     /db_xref="GeneID:851421"
                     /translation="MDTDLDVPMQDAVTEQLTPTVSEDMDLNNNSSDNNAEEFSVDDL
                     KPGSSGIADHKSSKPLELNNTNINQLDQWIEHLSKCEPLSEDDVARLCKMAVDVLQFE
                     ENVKPINVPVTICGDVHGQFHDLLELFKIGGPCPDTNYLFMGDYVDRGYYSVETVSYL
                     VAMKVRYPHRITILRGNHESRQITQVYGFYDECLRKYGSANVWKMFTDLFDYFPITAL
                     VDNKIFCLHGGLSPMIETIDQVRELNRIQEVPHEGPMCDLLWSDPDDRGGWGISPRGA
                     GFTFGQDVSEQFNHTNDLSLIARAHQLVMEGYAWSHQQNVVTIFSAPNYCYRCGNQAA
                     IMEVDENHNRQFLQYDPSVRPGEPSVSRKTPDYFL"
     gene            complement(<221724..>221801)
                     /gene="RPL41B"
                     /locus_tag="YDL133C-A"
                     /gene_synonym="RPL47B; YDL134C-A"
                     /db_xref="GeneID:851422"
     mRNA            complement(<221724..>221801)
                     /gene="RPL41B"
                     /locus_tag="YDL133C-A"
                     /gene_synonym="RPL47B; YDL134C-A"
                     /product="ribosomal 60S subunit protein L41B"
                     /transcript_id="NM_001180194.1"
                     /db_xref="GI:296143233"
                     /db_xref="GeneID:851422"
     CDS             complement(221724..221801)
                     /gene="RPL41B"
                     /locus_tag="YDL133C-A"
                     /gene_synonym="RPL47B; YDL134C-A"
                     /note="Ribosomal 60S subunit protein L41B; comprises only
                     25 amino acids; rpl41a rpl41b double null mutant is
                     viable; homologous to mammalian ribosomal protein L41, no
                     bacterial homolog; RPL41B has a paralog, RPL41A, that
                     arose from the whole genome duplication"
                     /codon_start=1
                     /product="ribosomal 60S subunit protein L41B"
                     /protein_id="NP_010148.1"
                     /db_xref="GI:6320068"
                     /db_xref="SGD:S000002293"
                     /db_xref="GeneID:851422"
                     /translation="MRAKWRKKRTRRLKRKRRKVRARSK"
     gene            <222427..>223740
                     /gene="SRF1"
                     /locus_tag="YDL133W"
                     /db_xref="GeneID:851423"
     mRNA            <222427..>223740
                     /gene="SRF1"
                     /locus_tag="YDL133W"
                     /product="Srf1p"
                     /transcript_id="NM_001180192.1"
                     /db_xref="GI:296143234"
                     /db_xref="GeneID:851423"
     CDS             222427..223740
                     /gene="SRF1"
                     /locus_tag="YDL133W"
                     /note="Regulator of phospholipase D (Spo14p); interacts
                     with Spo14p and regulates its catalytic activity; capable
                     of buffering the toxicity of C16:0 platelet activating
                     factor, a lipid that accumulates intraneuronally in
                     Alzheimer's patients"
                     /codon_start=1
                     /product="Srf1p"
                     /protein_id="NP_010149.1"
                     /db_xref="GI:6320069"
                     /db_xref="SGD:S000002291"
                     /db_xref="GeneID:851423"
                     /translation="MGDSNSSQEAYSDTTSTNASRIADQNQLNLNVDLEKNQTVRKSG
                     SLEALQNAKIHVPKHSDGSPLDYPKLNTYTFVPTTVPPYVLEAQFDKLRLQDKGTVDG
                     NVTDDKNLPKEFKWGQFASTIGCHSAYTRDQNYNPSHKSYDGYSLSSSTSSKNAALRE
                     ILGDMCSEWGGEERLEGVLHSEIGANLEFNTTEERKEWLQYIEKVKDFYYGDNKKNPE
                     SPESVHNKVYKSDWVNELNKEREKWRRLKQRKLQQWRPPLTSLLLDNQYLILGLRIFT
                     GILSCISLALAIKIFQNSRSNNTISESKIGQQPSTIMAICVNAVAIAYIIYIAHDEFA
                     GKPVGLRNPLSKLKLILLDLLFIIFSSANLALAFNTRFDKEWVCTSIRRSNGSTYGYP
                     KIPRICRKQEALSAFLFVALFMWVITFSISIVRVVEKVSSITNRN"
     gene            <224304..>226751
                     /gene="CDC53"
                     /locus_tag="YDL132W"
                     /db_xref="GeneID:851424"
     mRNA            <224304..>226751
                     /gene="CDC53"
                     /locus_tag="YDL132W"
                     /product="cullin CDC53"
                     /transcript_id="NM_001180191.1"
                     /db_xref="GI:296143235"
                     /db_xref="GeneID:851424"
     CDS             224304..226751
                     /gene="CDC53"
                     /locus_tag="YDL132W"
                     /note="Cullin; structural protein of SCF complexes (which
                     also contain Skp1p, Cdc34p, Hrt1p and an F-box protein)
                     involved in ubiquitination; SCF promotes the G1-S
                     transition by targeting G1 cyclins and the Cln-CDK
                     inhibitor Sic1p for degradation"
                     /codon_start=1
                     /product="cullin CDC53"
                     /protein_id="NP_010150.1"
                     /db_xref="GI:6320070"
                     /db_xref="SGD:S000002290"
                     /db_xref="GeneID:851424"
                     /translation="MSETLPRSDDLEATWNFIEPGINQILGNEKNQASTSKRVYKILS
                     PTMYMEVYTAIYNYCVNKSRSSGHFSTDSRTGQSTILVGSEIYEKLKNYLKNYILNFK
                     QSNSETFLQFYVKRWKRFTIGAIFLNHAFDYMNRYWVQKERSDGKRHIFDVNTLCLMT
                     WKEVMFDPSKDVLINELLDQVTLGREGQIIQRSNISTAIKSLVALGIDPQDLKKLNLN
                     VYIQVFEKPFLKKTQEYYTQYTNDYLEKHSVTEYIFEAHEIIKREEKAMTIYWDDHTK
                     KPLSMALNKVLITDHIEKLENEFVVLLDARDIEKITSLYALIRRDFTLIPRMASVFEN
                     YVKKTGENEISSLLAMHKHNIMKNENANPKKLALMTAHSLSPKDYIKKLLEVHDIFSK
                     IFNESFPDDIPLAKALDNACGAFININEFALPAGSPKSATSKTSEMLAKYSDILLKKA
                     TKPEVASDMSDEDIITIFKYLTDKDAFETHYRRLFAKRLIHGTSTSAEDEENIIQRLQ
                     AANSMEYTGKITKMFQDIRLSKILEDDFAVALKNEPDYSKAKYPDLQPFVLAENMWPF
                     SYQEVEFKLPKELVPSHEKLKESYSQKHNGRILKWLWPLCRGELKADIGKPGRMPFNF
                     TVTLFQMAILLLYNDADVLTLENIQEGTSLTIQHIAAAMVPFIKFKLIQQVPPGLDAL
                     VKPETQFKLSRPYKALKTNINFASGVKNDILQSLSGGGHDNHGNKLGNKRLTEDERIE
                     KELNTERQIFLEACIVRIMKAKRNLPHTTLVNECIAQSHQRFNAKVSMVKRAIDSLIQ
                     KGYLQRGDDGESYAYLA"
     gene            <227393..>228715
                     /gene="LYS21"
                     /locus_tag="YDL131W"
                     /db_xref="GeneID:851425"
     mRNA            <227393..>228715
                     /gene="LYS21"
                     /locus_tag="YDL131W"
                     /product="homocitrate synthase LYS21"
                     /transcript_id="NM_001180190.1"
                     /db_xref="GI:296143236"
                     /db_xref="GeneID:851425"
     CDS             227393..228715
                     /gene="LYS21"
                     /locus_tag="YDL131W"
                     /EC_number="2.3.3.14"
                     /note="Homocitrate synthase isozyme; catalyzes the
                     condensation of acetyl-CoA and alpha-ketoglutarate to form
                     homocitrate, which is the first step in the lysine
                     biosynthesis pathway; LYS21 has a paralog, LYS20, that
                     arose from the whole genome duplication"
                     /codon_start=1
                     /product="homocitrate synthase LYS21"
                     /protein_id="NP_010151.1"
                     /db_xref="GI:6320071"
                     /db_xref="SGD:S000002289"
                     /db_xref="GeneID:851425"
                     /translation="MSENNEFQSVTESTTAPTTSNPYGPNPADYLSNVKNFQLIDSTL
                     REGEQFANAFFDTEKKIEIARALDDFGVDYIELTSPVASEQSRKDCEAICKLGLKAKI
                     LTHIRCHMDDARVAVETGVDGVDVVIGTSKFLRQYSHGKDMNYIAKSAVEVIEFVKSK
                     GIEIRFSSEDSFRSDLVDLLNIYKTVDKIGVNRVGIADTVGCANPRQVYELIRTLKSV
                     VSCDIECHFHNDTGCAIANAYTALEGGARLIDVSVLGIGERNGITPLGGLMARMIVAA
                     PDYVRSKYKLHKIRDIENLVADAVEVNIPFNNPITGFCAFTHKAGIHAKAILANPSTY
                     EILDPHDFGMKRYIHFANRLTGWNAIKSRVDQLNLNLTDDQIKEVTAKIKKLGDVRPL
                     NIDDVDSIIKDFHAELSTPLLKPVNKGTDDDNIDISNGHVSKKAKVTK"
     gene            <229171..>229431
                     /gene="STF1"
                     /locus_tag="YDL130W-A"
                     /gene_synonym="AIS2"
                     /db_xref="GeneID:851426"
     mRNA            <229171..>229431
                     /gene="STF1"
                     /locus_tag="YDL130W-A"
                     /gene_synonym="AIS2"
                     /product="Stf1p"
                     /transcript_id="NM_001184325.1"
                     /db_xref="GI:296143237"
                     /db_xref="GeneID:851426"
     CDS             229171..229431
                     /gene="STF1"
                     /locus_tag="YDL130W-A"
                     /gene_synonym="AIS2"
                     /note="Protein involved in regulation of the mitochondrial
                     F1F0-ATP synthase; Stf1p and Stf2p act as stabilizing
                     factors that enhance inhibitory action of the Inh1p
                     protein; protein abundance increases in response to DNA
                     replication stress; STF1 has a paralog, INH1, that arose
                     from the whole genome duplication"
                     /codon_start=1
                     /product="Stf1p"
                     /protein_id="NP_010152.1"
                     /db_xref="GI:6320072"
                     /db_xref="SGD:S000007232"
                     /db_xref="GeneID:851426"
                     /translation="MLNRCISRNTRLPVNLRIASRFYSDGPLGGAGPGNPQDIFIKRE
                     RAKEDYYARQQEREQLAHVKEQLKEHKKKLENLENKINNLSK"
     gene            <229906..>230527
                     /gene="RPP1B"
                     /locus_tag="YDL130W"
                     /gene_synonym="RPL44'; RPLA3"
                     /db_xref="GeneID:851427"
     mRNA            join(<229906..230019,230321..>230527)
                     /gene="RPP1B"
                     /locus_tag="YDL130W"
                     /gene_synonym="RPL44'; RPLA3"
                     /product="ribosomal protein P1B"
                     /transcript_id="NM_001180189.1"
                     /db_xref="GI:296143238"
                     /db_xref="GeneID:851427"
     CDS             join(229906..230019,230321..230527)
                     /gene="RPP1B"
                     /locus_tag="YDL130W"
                     /gene_synonym="RPL44'; RPLA3"
                     /note="Ribosomal protein P1 beta; component of the
                     ribosomal stalk, which is involved in interaction of
                     translational elongation factors with ribosome; free
                     (non-ribosomal) P1 stimulates the phosphorylation of the
                     eIF2 alpha subunit (Sui2p) by Gcn2p; accumulation is
                     regulated by phosphorylation and interaction with the P2
                     stalk component"
                     /codon_start=1
                     /product="ribosomal protein P1B"
                     /protein_id="NP_010153.1"
                     /db_xref="GI:6320073"
                     /db_xref="SGD:S000002288"
                     /db_xref="GeneID:851427"
                     /translation="MSDSIISFAAFILADAGLEITSDNLLTITKAAGANVDNVWADVY
                     AKALEGKDLKEILSGFHNAGPVAGAGAASGAAAAGGDAAAEEEKEEEAAEESDDDMGF
                     GLFD"
     gene            <231024..>231899
                     /locus_tag="YDL129W"
                     /db_xref="GeneID:851428"
     mRNA            <231024..>231899
                     /locus_tag="YDL129W"
                     /product="hypothetical protein"
                     /transcript_id="NM_001180188.1"
                     /db_xref="GI:296143239"
                     /db_xref="GeneID:851428"
     CDS             231024..231899
                     /locus_tag="YDL129W"
                     /note="hypothetical protein; green fluorescent protein
                     (GFP)-fusion protein localizes to the cytoplasm and the
                     nucleus; YDL129W is not an essential gene; relative
                     distribution to the nucleus increases upon DNA replication
                     stress"
                     /codon_start=1
                     /product="hypothetical protein"
                     /protein_id="NP_010154.1"
                     /db_xref="GI:6320074"
                     /db_xref="SGD:S000002287"
                     /db_xref="GeneID:851428"
                     /translation="MELRSRRSAEAYLVTPEEPAKNKSERSIESNERVGTREAKSENT
                     SVFSPAYSDTATTDSSKKVDDNEYYNFTSHFMPSLKNTRELENTILNLIQRIKEGDDE
                     TLVSEKDLILSVLNRSLASTSHWKLQAQLSELRATSEGRYAVETNLLKKEVEFLKNKT
                     PKTNESASSAELRPLLERPLKRKLSLPGLAQRPLSTGARLEGGYGGVSPNSWKTKVPK
                     LPLPASRPSLNLSPQKVPTGTDKVEEDTKIDTLELVENNKPHPRMRRRSDNPATNEYV
                     RVFHLEKKEPKSRKK"
     gene            <232652..>233887
                     /gene="VCX1"
                     /locus_tag="YDL128W"
                     /gene_synonym="HUM1; MNR1"
                     /db_xref="GeneID:851429"
     mRNA            <232652..>233887
                     /gene="VCX1"
                     /locus_tag="YDL128W"
                     /gene_synonym="HUM1; MNR1"
                     /product="Vcx1p"
                     /transcript_id="NM_001180187.1"
                     /db_xref="GI:296143240"
                     /db_xref="GeneID:851429"
     CDS             232652..233887
                     /gene="VCX1"
                     /locus_tag="YDL128W"
                     /gene_synonym="HUM1; MNR1"
                     /note="Vacuolar membrane antiporter with Ca2+/H+ and K+/H+
                     exchange activity; involved in control of cytosolic Ca2+
                     and K+ concentrations; has similarity to sodium/calcium
                     exchangers, including the bovine Na+/Ca2+,K+ antiporter"
                     /codon_start=1
                     /product="Vcx1p"
                     /protein_id="NP_010155.1"
                     /db_xref="GI:6320075"
                     /db_xref="SGD:S000002286"
                     /db_xref="GeneID:851429"
                     /translation="MDATTPLLTVANSHPARNPKHTAWRAAVYDLQYILKASPLNFLL
                     VFVPLGLIWGHFQLSHTLTFLFNFLAIIPLAAILANATEELADKAGNTIGGLLNATFG
                     NAVELIVSIIALKKGQVRIVQASMLGSLLSNLLLVLGLCFIFGGYNRVQQTFNQTAAQ
                     TMSSLLAIACASLLIPAAFRATLPHGKEDHFIDGKILELSRGTSIVILIVYVLFLYFQ
                     LGSHHALFEQQEEETDEVMSTISRNPHHSLSVKSSLVILLGTTVIISFCADFLVGTID
                     NVVESTGLSKTFIGLIVIPIVGNAAEHVTSVLVAMKDKMDLALGVAIGSSLQVALFVT
                     PFMVLVGWMIDVPMTLNFSTFETATLFIAVFLSNYLILDGESNWLEGVMSLAMYILIA
                     MAFFYYPDEKTLDSIGNSL"
     gene            <234927..>235853
                     /gene="PCL2"
                     /locus_tag="YDL127W"
                     /gene_synonym="CLN4"
                     /db_xref="GeneID:851430"
     mRNA            <234927..>235853
                     /gene="PCL2"
                     /locus_tag="YDL127W"
                     /gene_synonym="CLN4"
                     /product="Pcl2p"
                     /transcript_id="NM_001180186.1"
                     /db_xref="GI:296143241"
                     /db_xref="GeneID:851430"
     CDS             234927..235853
                     /gene="PCL2"
                     /locus_tag="YDL127W"
                     /gene_synonym="CLN4"
                     /note="Cyclin, interacts with cyclin-dependent kinase
                     Pho85p; member of the Pcl1,2-like subfamily, involved in
                     the regulation of polarized growth and morphogenesis and
                     progression through the cell cycle; localizes to sites of
                     polarized cell growth; PCL2 has a paralog, PCL9, that
                     arose from the whole genome duplication"
                     /codon_start=1
                     /product="Pcl2p"
                     /protein_id="NP_010156.2"
                     /db_xref="GI:42742057"
                     /db_xref="SGD:S000002285"
                     /db_xref="GeneID:851430"
                     /translation="MSNYEALLKFNRKAVSKEMVQYLASTTASIIKIKKTNSMIDIAL
                     PAPPLTKFINRLIKHSNVQTPTLMATSVYLAKLRSIIPSNVYGIETTRHRIFLGCLIL
                     AAKTLNDSSPLNKHWAEYTDGLLILREVNTIERELLEYFDWDVTISTDDLITCLSPFL
                     KPIKEEQLYKSQRDCRTLKNFSAQEKDIVNKTSISHSRSSSNMSIPSLASTSTLSTLE
                     SRRSNLSNYSNRIRTLPELHESNNISDKFSPRTYNIDSKHDNKENRPIPTIKPFNFSK
                     ARPVILKTGLNKQIIKEDTKVKKSNWSNYFKS"
     gene            complement(<236157..>238664)
                     /gene="CDC48"
                     /locus_tag="YDL126C"
                     /db_xref="GeneID:851431"
     mRNA            complement(<236157..>238664)
                     /gene="CDC48"
                     /locus_tag="YDL126C"
                     /product="AAA family ATPase CDC48"
                     /transcript_id="NM_001180185.1"
                     /db_xref="GI:296143242"
                     /db_xref="GeneID:851431"
     CDS             complement(236157..238664)
                     /gene="CDC48"
                     /locus_tag="YDL126C"
                     /note="AAA ATPase; subunit of polyubiquitin-selective
                     segregase complex involved in ERAD, cell wall integrity
                     during heat stress, mitotic spindle disassembly; subunit
                     of complex involved in mitochondria-associated
                     degradation; role in mobilizing membrane bound
                     transcription factors by regulated
                     ubiquitin/proteasome-dependent processing, in
                     macroautophagy, PMN, RAD, ribophagy, homotypic ER membrane
                     fusion, disassembly of Met30p from SCF complex, functional
                     ortholog of human p97/VCP"
                     /codon_start=1
                     /product="AAA family ATPase CDC48"
                     /protein_id="NP_010157.1"
                     /db_xref="GI:6320077"
                     /db_xref="SGD:S000002284"
                     /db_xref="GeneID:851431"
                     /translation="MGEEHKPLLDASGVDPREEDKTATAILRRKKKDNMLLVDDAIND
                     DNSVIAINSNTMDKLELFRGDTVLVKGKKRKDTVLIVLIDDELEDGACRINRVVRNNL
                     RIRLGDLVTIHPCPDIKYATRISVLPIADTIEGITGNLFDVFLKPYFVEAYRPVRKGD
                     HFVVRGGMRQVEFKVVDVEPEEYAVVAQDTIIHWEGEPINREDEENNMNEVGYDDIGG
                     CRKQMAQIREMVELPLRHPQLFKAIGIKPPRGVLMYGPPGTGKTLMARAVANETGAFF
                     FLINGPEVMSKMAGESESNLRKAFEEAEKNAPAIIFIDEIDSIAPKRDKTNGEVERRV
                     VSQLLTLMDGMKARSNVVVIAATNRPNSIDPALRRFGRFDREVDIGIPDATGRLEVLR
                     IHTKNMKLADDVDLEALAAETHGYVGADIASLCSEAAMQQIREKMDLIDLDEDEIDAE
                     VLDSLGVTMDNFRFALGNSNPSALRETVVESVNVTWDDVGGLDEIKEELKETVEYPVL
                     HPDQYTKFGLSPSKGVLFYGPPGTGKTLLAKAVATEVSANFISVKGPELLSMWYGESE
                     SNIRDIFDKARAAAPTVVFLDELDSIAKARGGSLGDAGGASDRVVNQLLTEMDGMNAK
                     KNVFVIGATNRPDQIDPAILRPGRLDQLIYVPLPDENARLSILNAQLRKTPLEPGLEL
                     TAIAKATQGFSGADLLYIVQRAAKYAIKDSIEAHRQHEAEKEVKVEGEDVEMTDEGAK
                     AEQEPEVDPVPYITKEHFAEAMKTAKRSVSDAELRRYEAYSQQMKASRGQFSNFNFND
                     APLGTTATDNANSNNSAPSGAGAAFGSNAEEDDDLYS"
     gene            complement(<239019..>239606)
                     /gene="HNT1"
                     /locus_tag="YDL125C"
                     /db_xref="GeneID:851432"
     mRNA            complement(join(<239019..239398,239510..>239606))
                     /gene="HNT1"
                     /locus_tag="YDL125C"
                     /product="Hnt1p"
                     /transcript_id="NM_001180184.1"
                     /db_xref="GI:296143243"
                     /db_xref="GeneID:851432"
     CDS             complement(join(239019..239398,239510..239606))
                     /gene="HNT1"
                     /locus_tag="YDL125C"
                     /EC_number="3.-.-.-"
                     /note="Adenosine 5'-monophosphoramidase; interacts
                     physically and genetically with Kin28p, a CDK and TFIIK
                     subunit, and genetically with CAK1; member of the
                     histidine triad (HIT) superfamily of nucleotide-binding
                     proteins and similar to Hint; protein abundance increases
                     in response to DNA replication stress"
                     /codon_start=1
                     /product="Hnt1p"
                     /protein_id="NP_010158.1"
                     /db_xref="GI:6320078"
                     /db_xref="SGD:S000002283"
                     /db_xref="GeneID:851432"
                     /translation="MEPLISAPYLTTTKMSAPATLDAACIFCKIIKSEIPSFKLIETK
                     YSYAFLDIQPTAEGHALIIPKYHGAKLHDIPDEFLTDAMPIAKRLAKAMKLDTYNVLQ
                     NNGKIAHQEVDHVHFHLIPKRDEKSGLIVGWPAQETDFDKLGKLHKELLAKLEGSD"
     gene            <240259..>241197
                     /locus_tag="YDL124W"
                     /db_xref="GeneID:851433"
     mRNA            <240259..>241197
                     /locus_tag="YDL124W"
                     /product="aldo-keto reductase superfamily protein"
                     /transcript_id="NM_001180183.1"
                     /db_xref="GI:296143244"
                     /db_xref="GeneID:851433"
     CDS             240259..241197
                     /locus_tag="YDL124W"
                     /EC_number="1.2.1.-"
                     /note="NADPH-dependent alpha-keto amide reductase; reduces
                     aromatic alpha-keto amides, aliphatic alpha-keto esters,
                     and aromatic alpha-keto esters; member of the aldo-keto
                     reductase (AKR) family; protein abundance increases in
                     response to DNA replication stress"
                     /codon_start=1
                     /product="aldo-keto reductase superfamily protein"
                     /protein_id="NP_010159.1"
                     /db_xref="GI:6320079"
                     /db_xref="SGD:S000002282"
                     /db_xref="GeneID:851433"
                     /translation="MSFHQQFFTLNNGNKIPAIAIIGTGTRWYKNEETDATFSNSLVE
                     QIVYALKLPGIIHIDAAEIYRTYPEVGKALSLTEKPRNAIFLTDKYSPQIKMSDSPAD
                     GLDLALKKMGTDYVDLYLLHSPFVSKEVNGLSLEEAWKDMEQLYKSGKAKNIGVSNFA
                     VEDLQRILKVAEVKPQVNQIEFSPFLQNQTPGIYKFCQEHDILVEAYSPLGPLQKKTA
                     QDDSQPFFEYVKELSEKYIKSEAQIILRWVTKRGVLPVTTSSKPQRISDAQNLFSFDL
                     TAEEVDKITELGLEHEPLRLYWNKLYGKYNYAAQKV"
     gene            <241418..>241840
                     /gene="SNA4"
                     /locus_tag="YDL123W"
                     /db_xref="GeneID:851434"
     mRNA            <241418..>241840
                     /gene="SNA4"
                     /locus_tag="YDL123W"
                     /product="Sna4p"
                     /transcript_id="NM_001180182.1"
                     /db_xref="GI:296143245"
                     /db_xref="GeneID:851434"
     CDS             241418..241840
                     /gene="SNA4"
                     /locus_tag="YDL123W"
                     /note="hypothetical protein; localized to the vacuolar
                     outer membrane; predicted to be palmitoylated"
                     /codon_start=1
                     /product="Sna4p"
                     /protein_id="NP_010160.1"
                     /db_xref="GI:6320080"
                     /db_xref="SGD:S000002281"
                     /db_xref="GeneID:851434"
                     /translation="MCCYCVCCTVSDFILYIVAFFFPPAAVLLRSGPCSSDFLLNVLL
                     TLLGFLPGMLHAFYYITITSPLRNAEYVYYYQQGWVDSERNVPSNRPQNSQTPQNRPQ
                     QGSSARNVYPSVETPLLQGAAPHDNKQSLVESPPPYVP"
     gene            <242552..>244981
                     /gene="UBP1"
                     /locus_tag="YDL122W"
                     /db_xref="GeneID:851435"
     mRNA            <242552..>244981
                     /gene="UBP1"
                     /locus_tag="YDL122W"
                     /product="Ubp1p"
                     /transcript_id="NM_001180181.1"
                     /db_xref="GI:296143246"
                     /db_xref="GeneID:851435"
     CDS             242552..244981
                     /gene="UBP1"
                     /locus_tag="YDL122W"
                     /EC_number="3.4.19.12"
                     /note="Ubiquitin-specific protease; removes ubiquitin from
                     ubiquitinated proteins; cleaves at the C terminus of
                     ubiquitin fusions irrespective of their size; capable of
                     cleaving polyubiquitin chains"
                     /codon_start=1
                     /product="Ubp1p"
                     /protein_id="NP_010161.1"
                     /db_xref="GI:6320081"
                     /db_xref="SGD:S000002280"
                     /db_xref="GeneID:851435"
                     /translation="MDLFIESKINSLLQFLFGSRQDFLRNFKTWSNNNNNLSIYLLIF
                     GIVVFFYKKPDHLNYIVESVSEMTTNFRNNNSLSRWLPRSKFTHLDEEILKRGGFIAG
                     LVNDGNTCFMNSVLQSLASSRELMEFLDNNVIRTYEEIEQNEHNEEGNGQESAQDEAT
                     HKKNTRKGGKVYGKHKKKLNRKSSSKEDEEKSQEPDITFSVALRDLLSALNAKYYRDK
                     PYFKTNSLLKAMSKSPRKNILLGYDQEDAQEFFQNILAELESNVKSLNTEKLDTTPVA
                     KSELPDDALVGQLNLGEVGTVYIPTEQIDPNSILHDKSIQNFTPFKLMTPLDGITAER
                     IGCLQCGENGGIRYSVFSGLSLNLPNENIGSTLKLSQLLSDWSKPEIIEGVECNRCAL
                     TAAHSHLFGQLKEFEKKPEGSIPEKLINAVKDRVHQIEEVLAKPVIDDEDYKKLHTAN
                     MVRKCSKSKQILISRPPPLLSIHINRSVFDPRTYMIRKNNSKVLFKSRLNLAPWCCDI
                     NEINLDARLPMSKKEKAAQQDSSEDENIGGEYYTKLHERFEQEFEDSEEEKEYDDAEG
                     NYASHYNHTKDISNYDPLNGEVDGVTSDDEDEYIEETDALGNTIKKRIIEHSDVENEN
                     VKDNEELQEIDNVSLDEPKINVEDQLETSSDEEDVIPAPPINYARSFSTVPATPLTYS
                     LRSVIVHYGTHNYGHYIAFRKYRGCWWRISDETVYVVDEAEVLSTPGVFMLFYEYDFD
                     EETGKMKDDLEAIQSNNEEDDEKEQEQKGVQEPKESQEQGEGEEQEEGQEQMKFERTE
                     DHRDISGKDVN"
     gene            complement(<245133..>245582)
                     /locus_tag="YDL121C"
                     /db_xref="GeneID:851436"
     mRNA            complement(<245133..>245582)
                     /locus_tag="YDL121C"
                     /product="hypothetical protein"
                     /transcript_id="NM_001180180.1"
                     /db_xref="GI:296143247"
                     /db_xref="GeneID:851436"
     CDS             complement(245133..245582)
                     /locus_tag="YDL121C"
                     /note="hypothetical protein; green fluorescent protein
                     (GFP)-fusion protein localizes to the endoplasmic
                     reticulum; YDL121C is not an essential protein"
                     /codon_start=1
                     /product="hypothetical protein"
                     /protein_id="NP_010162.1"
                     /db_xref="GI:6320082"
                     /db_xref="SGD:S000002279"
                     /db_xref="GeneID:851436"
                     /translation="MNLYGYFLLLIIVIAFIALLPLFSGIGTFKLTKPKSSATAQSAT
                     GKLGKREYLKKKLDHTNVLKFDLKDTEESLGHDSASASSASRKFEIDSKTGLKRRVIG
                     QYNKDPNDFDFDIDDLINEDELDERREEEKKLKKYNGKKNEAYEGFV"
     gene            <245923..>246447
                     /gene="YFH1"
                     /locus_tag="YDL120W"
                     /db_xref="GeneID:851437"
     mRNA            <245923..>246447
                     /gene="YFH1"
                     /locus_tag="YDL120W"
                     /product="Yfh1p"
                     /transcript_id="NM_001180179.1"
                     /db_xref="GI:296143248"
                     /db_xref="GeneID:851437"
     CDS             245923..246447
                     /gene="YFH1"
                     /locus_tag="YDL120W"
                     /EC_number="1.16.3.1"
                     /note="Mitochondrial matrix iron chaperone; oxidizes and
                     stores iron; interacts with Isu1p to promote Fe-S cluster
                     assembly; mutation results in multiple Fe/S-dependent
                     enzyme deficiencies; human frataxin homolog is mutated in
                     Friedrich's ataxia"
                     /codon_start=1
                     /product="Yfh1p"
                     /protein_id="NP_010163.1"
                     /db_xref="GI:6320083"
                     /db_xref="SGD:S000002278"
                     /db_xref="GeneID:851437"
                     /translation="MIKRSLASLVRVSSVMGRRYMIAAAGGERARFCPAVTNKKNHTV
                     NTFQKRFVESSTDGQVVPQEVLNLPLEKYHEEADDYLDHLLDSLEELSEAHPDCIPDV
                     ELSHGVMTLEIPAFGTYVINKQPPNKQIWLASPLSGPNRFDLLNGEWVSLRNGTKLTD
                     ILTEEVEKAISKSQ"
     gene            complement(<246689..>247612)
                     /locus_tag="YDL119C"
                     /db_xref="GeneID:851439"
     mRNA            complement(<246689..>247612)
                     /locus_tag="YDL119C"
                     /product="hypothetical protein"
                     /transcript_id="NM_001180178.1"
                     /db_xref="GI:296143249"
                     /db_xref="GeneID:851439"
     CDS             complement(246689..247612)
                     /locus_tag="YDL119C"
                     /note="Putative mitochondrial transport protein;
                     GFP-fusion protein is induced in response to the
                     DNA-damaging agent MMS; the authentic, non-tagged protein
                     is detected in purified mitochondria"
                     /codon_start=1
                     /product="hypothetical protein"
                     /protein_id="NP_010164.1"
                     /db_xref="GI:6320085"
                     /db_xref="SGD:S000002277"
                     /db_xref="GeneID:851439"
                     /translation="MTEQATKPRNSSHLIGGFFGGLTSAVALQPLDLLKTRIQQDKKA
                     TLWKNLKEIDSPLQLWRGTLPSALRTSIGSALYLSCLNLMRSSLAKRRNAVPSLTNDS
                     NIVYNKSSSLPRLTMYENLLTGAFARGLVGYITMPITVIKVRYESTLYNYSSLKEAIT
                     HIYTKEGLFGFFRGFGATCLRDAPYAGLYVLLYEKSKQLLPMVLPSRFIHYNPEGGFT
                     TYTSTTVNTTSAVLSASLATTVTAPFDTIKTRMQLEPSKFTNSFNTFTSIVKNENVLK
                     LFSGLSMRLARKAFSAGIAWGIYEELVKRFM"
     gene            <248581..>251238
                     /gene="CYK3"
                     /locus_tag="YDL117W"
                     /db_xref="GeneID:851440"
     mRNA            <248581..>251238
                     /gene="CYK3"
                     /locus_tag="YDL117W"
                     /product="Cyk3p"
                     /transcript_id="NM_001180176.1"
                     /db_xref="GI:296143251"
                     /db_xref="GeneID:851440"
     CDS             248581..251238
                     /gene="CYK3"
                     /locus_tag="YDL117W"
                     /note="SH3-domain protein located in the bud neck and
                     cytokinetic actin ring; relocalizes from bud neck to
                     nucleus upon DNA replication stress; activates the chitin
                     synthase activity of Chs2p during cytokinesis; suppressor
                     of growth and cytokinesis defects of chs2 phospho-mutants"
                     /codon_start=1
                     /product="Cyk3p"
                     /protein_id="NP_010166.1"
                     /db_xref="GI:6320086"
                     /db_xref="SGD:S000002275"
                     /db_xref="GeneID:851440"
                     /translation="MATNLTSLKPPFKVKARYGWSGQTKGDLGFLEGDIMEVTRIAGS
                     WFYGKLLRNKKCSGYFPHNFVILLEERLNSSTENGRQPSKIVESFEKSNKVVIPPVPS
                     RYSDERPRPKKKLSSSMPNSPKKPVDSLTKARKAKSKEMVNEKNIYNTQSSRHHNNSA
                     PNLPLASHSKPQVRNFEESMNNPLPPLPPLPDLDNMRKTDKRAPKKSYSANDLHMARS
                     SREYNYYKDNQKFYDGFIPEKRYSLEEDSISSGLFSNSQYLNDSACSSENSFALMSDF
                     SATSAGSFARHKYAQSFSDSLQRSQNANGCSTKINDSQEFGDSNASSRNGKMGDILRK
                     IIIPKRNTNIYSSSVSSPKSPKAYPKLPDIQNLNLSATPDEARDWIAVKCHLNRARTL
                     TKYDKHPRYMRALEENRDLILHPQDSIYNGLNTNEVKGNTKPGLVDVELAELNIEYID
                     KMTWKRCIRDGTMTLDSWAQTTFSARYSTVLEKLRGIYIFCTEMFALTDDNGTSDFSA
                     EPQNLEKILYRKHCTPYELTWLFKKLANSLGITCEIVIGFLKTPSAINWEFKYNHCWL
                     RILVNKEWRFIDVILGNVTNPIHEFVNNRKIKKAENSYFLMAPLEMIYTHIPPREFEQ
                     HIVPSIDQLSALYLPLVFPSFFKNELKLYKFSTALSFLEDSEIYECSLEIPNDVEVFA
                     SVVIPTDNEEASSAYRNMELALTQIKKQKAESGRRIALIKAVLPPNVNKGSLYIHSGV
                     RGTQTSIANIHPLSMMVPLTHKGSNMKYEFVIKIPSESIQKIELYIVEPQSRYLFVGN
                     EYSFEVIQSPSDGIVYSSDEGPNQNRKQPMAIKSPSGRVHELVKSDPHFPYGTWKGSI
                     KIKEPGVWSALVIADSGIGWSVFAEWLCV"
     gene            <251566..>253746
                     /gene="NUP84"
                     /locus_tag="YDL116W"
                     /db_xref="GeneID:851441"
     mRNA            <251566..>253746
                     /gene="NUP84"
                     /locus_tag="YDL116W"
                     /product="Nup84p"
                     /transcript_id="NM_001180175.1"
                     /db_xref="GI:296143252"
                     /db_xref="GeneID:851441"
     CDS             251566..253746
                     /gene="NUP84"
                     /locus_tag="YDL116W"
                     /note="Subunit of the Nup84p subcomplex of the nuclear
                     pore complex (NPC); contributes to nucleocytoplasmic
                     transport and NPC biogenesis; also plays roles in several
                     processes that may require localization of genes or
                     chromosomes at the nuclear periphery, including
                     double-strand break repair, transcription and chromatin
                     silencing; homologous to human NUP107"
                     /codon_start=1
                     /product="Nup84p"
                     /protein_id="NP_010167.1"
                     /db_xref="GI:6320087"
                     /db_xref="SGD:S000002274"
                     /db_xref="GeneID:851441"
                     /translation="MELSPTYQTERFTKFSDTLKEFKIEQNNEQNPIDPFNIIREFRS
                     AAGQLALDLANSGDESNVISSKDWELEARFWHLVELLLVFRNADLDLDEMELHPYNSR
                     GLFEKKLMQDNKQLYQIWIVMVWLKENTYVMERPKNVPTSKWLNSITSGGLKSCDLDF
                     PLRENTNVLDVKDKEEDHIFFKYIYELILAGAIDEALEEAKLSDNISICMILCGIQEY
                     LNPVIDTQIANEFNTQQGIKKHSLWRRTVYSLSQQAGLDPYERAIYSYLSGAIPNQEV
                     LQYSDWESDLHIHLNQILQTEIENYLLENNQVGTDELILPLPSHALTVQEVLNRVASR
                     HPSESEHPIRVLMASVILDSLPSVIHSSVEMLLDVVKGTEASNDIIDKPYLLRIVTHL
                     AICLDIINPGSVEEVDKSKLITTYISLLKLQGLYENIPIYATFLNESDCLEACSFILS
                     SLEDPQVRKKQIETINFLRLPASNILRRTTQRVFDETEQEYSPSNEISISFDVNNIDM
                     HLIYGVEWLIEGKLYVDAVHSIIALSRRFLLNGRVKALEQFMERNNIGEICKNYELEK
                     IADNISKDENEDQFLEEITQYEHLIKGIREYEEWQKSVSLLSSESNIPTLIEKLQGFS
                     KDTFELIKTFLVDLTSSNFADSADYEILYEIRALYTPFLLMELHKKLVEAAKLLKIPK
                     FISEALAFTSLVANENDKIYLLFQSSGKLKEYLDLVARTATLSN"
     rep_origin      253791..254039
                     /note="ARS410;
                     Autonomously Replicating Sequence"
                     /db_xref="SGD:S000118431"
     gene            complement(<253995..>255126)
                     /gene="IWR1"
                     /locus_tag="YDL115C"
                     /db_xref="GeneID:851442"
     mRNA            complement(join(<253995..254974,255045..>255126))
                     /gene="IWR1"
                     /locus_tag="YDL115C"
                     /product="Iwr1p"
                     /transcript_id="NM_001180174.1"
                     /db_xref="GI:296143253"
                     /db_xref="GeneID:851442"
     CDS             complement(join(253995..254974,255045..255126))
                     /gene="IWR1"
                     /locus_tag="YDL115C"
                     /note="RNA polymerase II transport factor, conserved from
                     yeast to humans; also has a role in transporting RNA
                     polymerase III into the nucleus; interacts with most of
                     the RNAP II subunits; nucleo-cytoplasmic shuttling
                     protein; deletion causes hypersensitivity to K1 killer
                     toxin; protein increases in abundance and relocalizes from
                     nucleus to cytoplasm upon DNA replication stress"
                     /codon_start=1
                     /product="Iwr1p"
                     /protein_id="NP_010168.4"
                     /db_xref="GI:154199603"
                     /db_xref="SGD:S000002273"
                     /db_xref="GeneID:851442"
                     /translation="MSTISTTTAPEFIRVKRRRDEDSVQALLIDEGKRVKKQKFIFKL
                     SKTVSSESYQSEQESSTPLLKLAHEDHRHFVLEQRKKSRRDSDDEKSQQRLAAEGSTV
                     DDDGLPPEINQMVNDYLKLNKGVEKTERKKPSRKYFTGDSAKIASLPSLDYVFDIYHL
                     EKIHDDEVARYNNEKNIGFVKIIEHIDLALDEESDPNEARSDDEDSNDENYYQNDYPE
                     DEDDDRSILFGSEGEDIAALGEEIVIGVNKSRFSSWNDDKIQGSNGYHDVEEEYGDLF
                     NRLGGKSDVLKSINSSNFIDLDGQEGEIEISDNEDDSDEGDDIEYPRNEFFPTDVDDP
                     LAHHRDRIFHQLQKKINRS"
     gene            <255604..>256530
                     /locus_tag="YDL114W"
                     /db_xref="GeneID:851444"
     mRNA            <255604..>256530
                     /locus_tag="YDL114W"
                     /product="short-chain dehydrogenase/reductase"
                     /transcript_id="NM_001180173.1"
                     /db_xref="GI:296143254"
                     /db_xref="GeneID:851444"
     CDS             255604..256530
                     /locus_tag="YDL114W"
                     /EC_number="1.-.-.-"
                     /note="Putative short-chain dehydrogenase/reductase;
                     YDL114W is not an essential gene"
                     /codon_start=1
                     /product="short-chain dehydrogenase/reductase"
                     /protein_id="NP_010169.1"
                     /db_xref="GI:6320089"
                     /db_xref="SGD:S000002272"
                     /db_xref="GeneID:851444"
                     /translation="MVRKNKINRASGTTKHLKDFPSVILSLPSYNPSILSKNATALIT
                     GGSSGLGFELAKELSRRINKVIVADIQSFPTFAQVEYNNIFYYQCDITSLDEIKNLKK
                     AIERDHGNINIIINNAGVAHIKKLEHMTNKEVEQLIDINLIGAYRIISTFAEDMIDNR
                     EGFIINIASVLGELTPARLTSYGASKGAMIGFHKCMSRHFRSLSTECNKTGIKTLLVC
                     PGKIKTNMFIDVPTPSKLLAPDIIPSQLALAIISAMEHNHLQTLNAPYYVNLVPFFKT
                     LSWPYRHLLKHFSGMDHVTSTSPRAINPKRSA"
     rep_origin      256530..256633
                     /note="ARS411;
                     Putative replication origin; identified in multiple array
                     studies, not yet confirmed by plasmid-based assay"
                     /db_xref="SGD:S000130171"
     gene            complement(<256633..>258555)
                     /gene="ATG20"
                     /locus_tag="YDL113C"
                     /gene_synonym="CVT20; SNX42"
                     /db_xref="GeneID:851445"
     mRNA            complement(<256633..>258555)
                     /gene="ATG20"
                     /locus_tag="YDL113C"
                     /gene_synonym="CVT20; SNX42"
                     /product="Atg20p"
                     /transcript_id="NM_001180172.1"
                     /db_xref="GI:296143255"
                     /db_xref="GeneID:851445"
     CDS             complement(256633..258555)
                     /gene="ATG20"
                     /locus_tag="YDL113C"
                     /gene_synonym="CVT20; SNX42"
                     /note="Sorting nexin family member; required for the
                     cytoplasm-to-vacuole targeting (Cvt) pathway and for
                     endosomal sorting; has a Phox homology domain that binds
                     phosphatidylinositol-3-phosphate; interacts with Snx4p;
                     potential Cdc28p substrate"
                     /codon_start=1
                     /product="Atg20p"
                     /protein_id="NP_010170.1"
                     /db_xref="GI:6320090"
                     /db_xref="SGD:S000002271"
                     /db_xref="GeneID:851445"
                     /translation="MSDLNDVQENAKLNSETRNTGKAEPPHGTTEYVAEAEISKNGVG
                     SPKKSPKKGKVGKGDNNKVETELVHTALLEKDNPFMEEGPTGFTKSALLEIPGMRSHN
                     LKNPNEDYEDDSEGLLPLNQESNAETCRTSLSGSINSMNGETSASEEPSVSNRKKSAR
                     IHILEAKRVSEGQGRAYIAYVIQFENSTVQRRYSDFESLRSILIRLFPMTLIPPIPEK
                     QSIKNYGKSITGSSSKYLLPSEGSGSVDLSLSVIHASVNNSDEKLIRHRIRMLTEFLN
                     KLLTNEEITKTSIITDFLDPNNHNWHEFVNSSSTFSSLPKSILQCNPLDPTNTTRIHA
                     MLPIPGSSSQLLLNKESNDKKMDKERSKSFTNIEQDYKQYENLLDNGIYKYNRRTTKT
                     YHDLKSDYNEIGEVFAQFAHEQAQVGELAEQLSYLSNAFSGSSISLEKLVGRLYYNIN
                     EPLNESVHMATSARELIKYRKLKYLQNEMIKKSLNSKRAQLEKLEAQNNEYKDVDKII
                     DNEMSKSHTINLERPNNNTGSGGKSYGGKLFNGFNKLASMVKDSVKYQETDPHTASIN
                     LKKEIEQLSESLEVTENDLEVISKVIKNDQLPKFSKEREVDLSEILKHYSRYMRNYAR
                     QNLEIWKEVKRHQDFA"
     gene            <258915..>263225
                     /gene="TRM3"
                     /locus_tag="YDL112W"
                     /db_xref="GeneID:851446"
     mRNA            <258915..>263225
                     /gene="TRM3"
                     /locus_tag="YDL112W"
                     /product="Trm3p"
                     /transcript_id="NM_001180171.1"
                     /db_xref="GI:296143256"
                     /db_xref="GeneID:851446"
     CDS             258915..263225
                     /gene="TRM3"
                     /locus_tag="YDL112W"
                     /EC_number="2.1.1.34"
                     /note="2'-O-ribose methyltransferase; catalyzes the ribose
                     methylation of the guanosine nucleotide at position 18 of
                     tRNAs"
                     /codon_start=1
                     /product="Trm3p"
                     /protein_id="NP_010171.1"
                     /db_xref="GI:6320091"
                     /db_xref="SGD:S000002270"
                     /db_xref="GeneID:851446"
                     /translation="MVGGALICKYLPREEQLKLISDLIQNDSLEEVLELIETSPLDIT
                     TDSNIETPIFEKITEQVIAYASIDGEAREMFRSSRAEMNKALRTSAQLLCCLPSVWHK
                     FQVWMSYRLNDIISENYKHLFNDNFGKKIVQPFFDSFAEEQNANIKHENLHLDILSLL
                     HYLEVVYLFDECKNGISSKCLDFIIVPLLGCNSEEIADSCSKLMRWHIKYLSKCCNTD
                     SNFDKLIWTFIKQLYAEGSQQAWKQKNSLSFLLRFLLAAELSPELITYIKTDAYWRHI
                     QTELDNDVHEHRKLALSILKLTIQKLSSHGITLQTTFYKCNDLANIEMLGSWKKFTTL
                     YEMIALDTSLNQIQAAKQDIIKIFDNEHLHHSWGLILLSTGLKSSMESVRKYMMTLMF
                     SITNMSAFSSNLPLLTKTLLPAAMSAHYFDVKGVSCPHGEKLSLFVNNLLSQTTEGIS
                     DILFEILKLLVEKGTSFDPSRIYLSYGILVFFQNNKQKTINSDHLSLIRKLYDFAAEE
                     EVLETTIQTIYLKFLLYIDPSVSASELLFTLVSHIKLKGGTYKYVEPLFEDYRDLAVS
                     HFDDLQAKENLTTNIGKDTIFDLLASIIFDFKDIDITPDFLIEVAKSKQDIPVYTSKA
                     VTFLTQLLSGEPSNGYTYENATALLSYPNFTISTWKSINVNNLFKSVMEKFSLDKFKF
                     FAEIYQKTYECRFDTIELNFNDLLSLYEMVKKSANQCSRESFKVKDSAYSSYFELLNT
                     FLKTYALNRDSSEGNDDELHILLRLVDENINKDNGNYLGNLAVCKLLYFIIDSYIHCS
                     TSVSDDDIFIVKFIFEKFSFIWECINSERLVLKERDLHLMLIKGLFHPVILYFGSNQY
                     IDTLTSKLEEHAQTIISLSYSRRSLLPLLGSQLRVFMKFYGKLLREDVNYWWLINIIV
                     GVFKQPQMDVNLYKLKPVISSLFDHKLNNYYIKGDELYEKVYGPDEILARVSIIDSIL
                     YANDQLKIRLIEKVTEKTNALYAIKRTDGAEALQRLLQWQLLLLSLLTTNEKKLSETS
                     MIRILKSIEDESSPLVRVYKEWFISSKVVDYYKTGNPKFAEDYLFSLLEDHSKPVFVV
                     SAEKICFMVLKDLRNDEKKYGFTQLLDRFICTLVPNAASNKPLVRHFSNSLIISLWPT
                     FKAYLSDHTLRNIIENLYSNAKKTQIFGQYRAGDANIWDLKGDRKLTNMFGGVLKKVT
                     DHDCPYISESVFEKYLQEKDIVPIGTDERSLWLDKRDTNTESVNNANISCDTSPLQTK
                     SGAWETVLDLDNKKSNDVVTRSELIVVSSLVDKPPNLGGICRLCDVLGVGLLTVQDIK
                     VKNHPQFKNVAVTADRWMPMEEVALDEIASFMKEKKKEGYTLIGLEQTDKSVKLDNNF
                     QFPKKSLILLGTEAFGIPGTLLSELDLCLEIQQFGVIRSMNIQTATAVIVHSYTVQHM
                     "
     gene            complement(<263313..>264110)
                     /gene="RRP42"
                     /locus_tag="YDL111C"
                     /db_xref="GeneID:851447"
     mRNA            complement(<263313..>264110)
                     /gene="RRP42"
                     /locus_tag="YDL111C"
                     /product="Rrp42p"
                     /transcript_id="NM_001180170.1"
                     /db_xref="GI:296143257"
                     /db_xref="GeneID:851447"
     CDS             complement(263313..264110)
                     /gene="RRP42"
                     /locus_tag="YDL111C"
                     /note="Exosome non-catalytic core component; involved in
                     3'-5' RNA processing and degradation in both the nucleus
                     and the cytoplasm; has similarity to E. coli RNase PH and
                     to human hRrp42p (EXOSC7)"
                     /codon_start=1
                     /product="Rrp42p"
                     /protein_id="NP_010172.1"
                     /db_xref="GI:6320092"
                     /db_xref="SGD:S000002269"
                     /db_xref="GeneID:851447"
                     /translation="MSLSVAEKSYLYDSLASTPSIRPDGRLPHQFRPIEIFTDFLPSS
                     NGSSRIIASDGSECIVSIKSKVVDHHVENELLQVDVDIAGQRDDALVVETITSLLNKV
                     LKSGSGVDSSKLQLTKKYSFKIFVDVLVISSHSHPVSLISFAIYSALNSTYLPKLISA
                     FDDLEVEELPTFHDYDMVKLDINPPLVFILAVVGNNMLLDPAANESEVANNGLIISWS
                     NGKITSPIRSVALNDSNVKSFKPHLLKQGLAMVEKYAPDVVRSLENL"
     gene            complement(<264512..>264964)
                     /gene="TMA17"
                     /locus_tag="YDL110C"
                     /db_xref="GeneID:851448"
     mRNA            complement(<264512..>264964)
                     /gene="TMA17"
                     /locus_tag="YDL110C"
                     /product="Tma17p"
                     /transcript_id="NM_001180169.1"
                     /db_xref="GI:296143258"
                     /db_xref="GeneID:851448"
     CDS             complement(264512..264964)
                     /gene="TMA17"
                     /locus_tag="YDL110C"
                     /note="hypothetical protein that associates with
                     ribosomes; heterozygous deletion demonstrated increases in
                     chromosome instability in a rad9 deletion background;
                     protein abundance is decreased upon intracellular iron
                     depletion"
                     /codon_start=1
                     /product="Tma17p"
                     /protein_id="NP_010173.1"
                     /db_xref="GI:6320093"
                     /db_xref="SGD:S000002268"
                     /db_xref="GeneID:851448"
                     /translation="MCSAGGIRRPIQIEEFKTAISGMSDMELAQIKTEIENSINHLQR
                     SNARLGKYIAKLEGADDRLEADDSDDLENIDSGDLALYKDSVRENEIVLNNYNERVDA
                     LEQETVYRKTGHGKSKHEVEAKDNTNKGPDVDMDNSNVDVVTPNSIFI"
     gene            complement(<265258..>267201)
                     /locus_tag="YDL109C"
                     /db_xref="GeneID:851449"
     mRNA            complement(<265258..>267201)
                     /locus_tag="YDL109C"
                     /product="putative lipase"
                     /transcript_id="NM_001180168.1"
                     /db_xref="GI:296143259"
                     /db_xref="GeneID:851449"
     CDS             complement(265258..267201)
                     /locus_tag="YDL109C"
                     /EC_number="3.1.-.-"
                     /note="Putative lipase; involved in lipid metabolism; not
                     an essential gene; YDL109C has a paralog, ROG1, that arose
                     from the whole genome duplication"
                     /codon_start=1
                     /product="putative lipase"
                     /protein_id="NP_010174.1"
                     /db_xref="GI:6320094"
                     /db_xref="SGD:S000002267"
                     /db_xref="GeneID:851449"
                     /translation="MEAGRSADEVLYHNQSSVKLGELERYVITYELYQGDSIPADITL
                     DSLWVKIKNTTKLSYKPAYLLGPFILYCDVRAKDYESSYKIICSADKPVFQSNLQAQQ
                     KFIAELSLHHIKPRYVWIVDIVSQILFNKETKVTFEIVVGNSKASLKRKIRCNDSLPD
                     KACNILHTGLSVHRLTTADIWKVPRPIDMSQKSHLVILTHGFQSNVSADMEYLMEEIY
                     KAQMNNPNERLVIKGYMKNACETEKGIKFLGVGLANYIIDELYDDSVGKISFIGHSLG
                     GLTQTFAICYIKTKYPYFFKKVEPINFISLASPLLGIATSTPNYVKMSLSMGIIGTTG
                     QELGLKDGNYGDKPLLYLLSEESLISVLARFKRRTLYANAVNDGIVPLYSSSLLFLDY
                     SQLLQKLGGQTTAPCDPLFQPEVSPIGELPNHSDVANDDDGINASSWNTFWKSKENNC
                     DKKSKRLMNASVIKSMKSVLLSPCPDAKFFSDPDARVATIIHDKIYTEKNLPPPSPTL
                     YEGTAAKEGETRKTRKEMEEIIARRWHKGMHWRKVVVLLKPDAHNNIIVRRRFSNAYG
                     WPVVDHLVTAHFQRDDPIASPMQDKQFAEEDINMATGGVEPNKFYSWLTKIEDPSVYH
                     GGIVSTASQLASSWISKHSSVTD"
     gene            <267698..>268699
                     /gene="KIN28"
                     /locus_tag="YDL108W"
                     /db_xref="GeneID:851450"
     mRNA            join(<267698..267725,267807..>268699)
                     /gene="KIN28"
                     /locus_tag="YDL108W"
                     /product="TFIIH complex serine/threonine-protein kinase
                     subunit KIN28"
                     /transcript_id="NM_001180167.1"
                     /db_xref="GI:296143260"
                     /db_xref="GeneID:851450"
     CDS             join(267698..267725,267807..268699)
                     /gene="KIN28"
                     /locus_tag="YDL108W"
                     /EC_number="2.7.11.23"
                     /note="Serine/threonine protein kinase, subunit of
                     transcription factor TFIIH; involved in transcription
                     initiation at RNA polymerase II promoters; phosphorylates
                     Ser5 residue of the PolII C-terminal domain (CTD) at gene
                     promoters; relocalizes to the cytosol in response to
                     hypoxia"
                     /codon_start=1
                     /product="TFIIH complex serine/threonine-protein kinase
                     subunit KIN28"
                     /protein_id="NP_010175.1"
                     /db_xref="GI:6320095"
                     /db_xref="SGD:S000002266"
                     /db_xref="GeneID:851450"
                     /translation="MKVNMEYTKEKKVGEGTYAVVYLGCQHSTGRKIAIKEIKTSEFK
                     DGLDMSAIREVKYLQEMQHPNVIELIDIFMAYDNLNLVLEFLPTDLEVVIKDKSILFT
                     PADIKAWMLMTLRGVYHCHRNFILHRDLKPNNLLFSPDGQIKVADFGLARAIPAPHEI
                     LTSNVVTRWYRAPELLFGAKHYTSAIDIWSVGVIFAELMLRIPYLPGQNDVDQMEVTF
                     RALGTPTDRDWPEVSSFMTYNKLQIYPPPSRDELRKRFIAASEYALDFMCGMLTMNPQ
                     KRWTAVQCLESDYFKELPPPSDPSSIKIRN"
     gene            <268921..>269976
                     /gene="MSS2"
                     /locus_tag="YDL107W"
                     /db_xref="GeneID:851451"
     mRNA            <268921..>269976
                     /gene="MSS2"
                     /locus_tag="YDL107W"
                     /product="Mss2p"
                     /transcript_id="NM_001180166.1"
                     /db_xref="GI:296143261"
                     /db_xref="GeneID:851451"
     CDS             268921..269976
                     /gene="MSS2"
                     /locus_tag="YDL107W"
                     /note="Peripherally bound inner membrane protein of the
                     mitochondrial matrix; involved in membrane insertion of
                     C-terminus of Cox2p, interacts genetically and physically
                     with Cox18p"
                     /codon_start=1
                     /product="Mss2p"
                     /protein_id="NP_010176.1"
                     /db_xref="GI:6320096"
                     /db_xref="SGD:S000002265"
                     /db_xref="GeneID:851451"
                     /translation="MQRFVSKFVSTPPVPKKFQEIFPKKRTVNKILFQLDTRLTYHEM
                     YPIFLQVSQNTNEENIPWRKKYPYIRSSDIMQMRNVLITLRTQNKFVHKDLLAMEDKL
                     LNIAAELGNNDAISILSFNVIHEYKKENVKSSYEKDIETANEFIKKLYARNHHLTVKL
                     IGDLFFENKTYDKAEKYYQEFLKLENSTKLAGEVHGKLGEIQIKQVNGFLKAEKSWLS
                     CIELLEIERSSRWYFLLARLYMSSEPMKAKALLENCASIGFKECFKTLGFLELNYFNN
                     YERAKEWFKTGMEIMDLECFFGFFDCCVKEENFKGARDCLESVKKLGNDKDKKTMINV
                     FLESRKDSIKLLDKARL"
     gene            complement(<270222..>271901)
                     /gene="PHO2"
                     /locus_tag="YDL106C"
                     /gene_synonym="BAS2; GRF10"
                     /db_xref="GeneID:851452"
     mRNA            complement(<270222..>271901)
                     /gene="PHO2"
                     /locus_tag="YDL106C"
                     /gene_synonym="BAS2; GRF10"
                     /product="Pho2p"
                     /transcript_id="NM_001180165.1"
                     /db_xref="GI:296143262"
                     /db_xref="GeneID:851452"
     CDS             complement(270222..271901)
                     /gene="PHO2"
                     /locus_tag="YDL106C"
                     /gene_synonym="BAS2; GRF10"
                     /note="Homeobox transcription factor; regulatory targets
                     include genes involved in phosphate metabolism; binds
                     cooperatively with Pho4p to the PHO5 promoter;
                     phosphorylation of Pho2p facilitates interaction with
                     Pho4p; relocalizes to the cytosol in response to hypoxia"
                     /codon_start=1
                     /product="Pho2p"
                     /protein_id="NP_010177.1"
                     /db_xref="GI:6320097"
                     /db_xref="SGD:S000002264"
                     /db_xref="GeneID:851452"
                     /translation="MMEEFSYDHDFNTHFATDLDYLQHDQQQQQQQQHDQQHNQQQQP
                     QPQPIQTQNLEHDHDQHTNDMSASSNASDSGPQRPKRTRAKGEALDVLKRKFEINPTP
                     SLVERKKISDLIGMPEKNVRIWFQNRRAKLRKKQHGSNKDTIPSSQSRDIANDYDRGS
                     TDNNLVTTTSTSSIFHDEDLTFFDRIPLNSNNNYYFFDICSITVGSWNRMKSGALQRR
                     NFQSIKELRNLSPIKINNIMSNATDLMVLISKKNSEINYFFSAMANNTKILFRIFFPL
                     SSVTNCSLTLETDDDIINSNNTSDKNNSNTNNDDDNDDNSNEDNDNSSEDKRNAKDNF
                     GELKLTVTRSPTFAVYFLNNAPDEDPNLNNQWSICDDFSEGRQVNDAFVGGSNIPHTL
                     KGLQKSLRFMNSLILDYKSSNEILPTINTAIPTAAVPQQNIAPPFLNTNSSATDSNPN
                     TNLEDSLFFDHDLLSSSITNTNNGQGSNNGRQASKDDTLNLLDTTVNSNNNHNANNEE
                     NHLAQEHLSNDADIVANPNDHLLSLPTDSELPNTPDFLKNTNELTDEHRWI"
     gene            <272389..>273597
                     /gene="NSE4"
                     /locus_tag="YDL105W"
                     /gene_synonym="QRI2"
                     /db_xref="GeneID:851453"
     mRNA            <272389..>273597
                     /gene="NSE4"
                     /locus_tag="YDL105W"
                     /gene_synonym="QRI2"
                     /product="Nse4p"
                     /transcript_id="NM_001180164.1"
                     /db_xref="GI:296143263"
                     /db_xref="GeneID:851453"
     CDS             272389..273597
                     /gene="NSE4"
                     /locus_tag="YDL105W"
                     /gene_synonym="QRI2"
                     /note="Component of the SMC5-SMC6 complex; this complex
                     plays a key role in the removal of X-shaped DNA structures
                     that arise between sister chromatids during DNA
                     replication and repair"
                     /codon_start=1
                     /product="Nse4p"
                     /protein_id="NP_010178.1"
                     /db_xref="GI:6320098"
                     /db_xref="SGD:S000002263"
                     /db_xref="GeneID:851453"
                     /translation="MSSTVISRKRRNSTVTEPDSSGETRKQKKSRSDEKSSSSKDGDP
                     QLEFKVLQGYRDLESEMHKGRAQVTRTGDIGVAMDNLNAVDSLFNKVIGIKNNGLFAH
                     DARAMVSISELAQISVRNLKFDDSRSMVNLENIVNSLKRYMLKEHFKLNNIAENRNDL
                     TLAADEQSAADQQEESDGDIDRTPDDNHTDKATSSFKATSMRHSYLQQFSHYNEFSQF
                     NWFRIGALYNTISKNAPITDHLMGPLSIEKKPRVLTQRRRNNDQVGEKITAEKITQHS
                     LNSTQQETTPEQVKKCFKKLSKKLGPEGSINLFKFIIDPNSFSRSIENLFYTSFLIKE
                     GKLLMEHDEEGLPTIKIKQSISHTDSRSKEIERQRRRAAHQNHIIFQMDMPTWRKLIK
                     KYNITSPFLD"
     gene            complement(<273653..>274876)
                     /gene="QRI7"
                     /locus_tag="YDL104C"
                     /db_xref="GeneID:851454"
     mRNA            complement(<273653..>274876)
                     /gene="QRI7"
                     /locus_tag="YDL104C"
                     /product="Qri7p"
                     /transcript_id="NM_001180163.1"
                     /db_xref="GI:296143264"
                     /db_xref="GeneID:851454"
     CDS             complement(273653..274876)
                     /gene="QRI7"
                     /locus_tag="YDL104C"
                     /EC_number="2.3.1.-"
                     /EC_number="2.6.99.4"
                     /EC_number="3.4.24.-"
                     /note="Protein involved in threonylcarbamoyl adenosine
                     biosynthesis; Sua5p and Qri7p are necessary and sufficient
                     for RNA t6A modification in vitro; highly conserved
                     mitochondrial protein; essential for t6A modification of
                     mitochondrial tRNAs that decode ANN codons; similar to
                     Kae1p and E. coli YgjD, both of which are also required
                     for tRNA t6A modification; when directed to the cytoplasm,
                     complements the essential function of Kae1p in the KEOPS
                     complex"
                     /codon_start=1
                     /product="Qri7p"
                     /protein_id="NP_010179.1"
                     /db_xref="GI:6320099"
                     /db_xref="SGD:S000002262"
                     /db_xref="GeneID:851454"
                     /translation="MISIKGTGRFLLDNYRIWQRRAFNRPIQLRKGYKVLAIETSCDD
                     TCVSVLDRFSKSAAPNVLANLKDTLDSIDEGGIIPTKAHIHHQARIGPLTERALIESN
                     AREGIDLICVTRGPGMPGSLSGGLDFAKGLAVAWNKPLIGVHHMLGHLLIPRMGTNGK
                     VPQFPFVSLLVSGGHTTFVLSRAIDDHEILCDTIDIAVGDSLDKCGRELGFKGTMIAR
                     EMEKFINQDINDQDFALKLEMPSPLKNSASKRNMLSFSFSAFITALRTNLTKLGKTEI
                     QELPEREIRSIAYQVQESVFDHIINKLKHVLKSQPEKFKNVREFVCSGGVSSNQRLRT
                     KLETELGTLNSTSFFNFYYPPMDLCSDNSIMIGWAGIEIWESLRLVSDLDICPIRQWP
                     LNDLLSVDGWRTDQL"
     gene            complement(<275148..>276581)
                     /gene="QRI1"
                     /locus_tag="YDL103C"
                     /gene_synonym="UAP1"
                     /db_xref="GeneID:851455"
     mRNA            complement(<275148..>276581)
                     /gene="QRI1"
                     /locus_tag="YDL103C"
                     /gene_synonym="UAP1"
                     /product="UDP-N-acetylglucosamine diphosphorylase"
                     /transcript_id="NM_001180162.1"
                     /db_xref="GI:296143265"
                     /db_xref="GeneID:851455"
     CDS             complement(275148..276581)
                     /gene="QRI1"
                     /locus_tag="YDL103C"
                     /gene_synonym="UAP1"
                     /EC_number="2.7.7.23"
                     /note="UDP-N-acetylglucosamine pyrophosphorylase;
                     catalyzes the formation of UDP-N-acetylglucosamine
                     (UDP-GlcNAc), which is important in cell wall
                     biosynthesis, protein N-glycosylation, and GPI anchor
                     biosynthesis; protein abundance increases in response to
                     DNA replication stress"
                     /codon_start=1
                     /product="UDP-N-acetylglucosamine diphosphorylase"
                     /protein_id="NP_010180.1"
                     /db_xref="GI:6320100"
                     /db_xref="SGD:S000002261"
                     /db_xref="GeneID:851455"
                     /translation="MTDTKQLFIEAGQSQLFHNWESLSRKDQEELLSNLEQISSKRSP
                     AKLLEDCQNAIKFSLANSSKDTGVEISPLPPTSYESLIGNSKKENEYWRLGLEAIGKG
                     EVAVILMAGGQGTRLGSSQPKGCYDIGLPSKKSLFQIQAEKLIRLQDMVKDKKVEIPW
                     YIMTSGPTRAATEAYFQEHNYFGLNKEQITFFNQGTLPAFDLTGKHFLMKDPVNLSQS
                     PDGNGGLYRAIKENKLNEDFDRRGIKHVYMYCVDNVLSKIADPVFIGFAIKHGFELAT
                     KAVRKRDAHESVGLIATKNEKPCVIEYSEISNELAEAKDKDGLLKLRAGNIVNHYYLV
                     DLLKRDLDQWCENMPYHIAKKKIPAYDSVTGKYTKPTEPNGIKLEQFIFDVFDTVPLN
                     KFGCLEVDRCKEFSPLKNGPGSKNDNPETSRLAYLKLGTSWLEDAGAIVKDGVLVEVS
                     SKLSYAGENLSQFKGKVFDRSGIVLEK"
     gene            <276872..>280165
                     /gene="POL3"
                     /locus_tag="YDL102W"
                     /gene_synonym="CDC2; HPR6; TEX1"
                     /db_xref="GeneID:851456"
     mRNA            <276872..>280165
                     /gene="POL3"
                     /locus_tag="YDL102W"
                     /gene_synonym="CDC2; HPR6; TEX1"
                     /product="DNA-directed DNA polymerase delta POL3"
                     /transcript_id="NM_001180161.2"
                     /db_xref="GI:330443502"
                     /db_xref="GeneID:851456"
     CDS             276872..280165
                     /gene="POL3"
                     /locus_tag="YDL102W"
                     /gene_synonym="CDC2; HPR6; TEX1"
                     /EC_number="2.7.7.7"
                     /note="Catalytic subunit of DNA polymerase delta; required
                     for chromosomal DNA replication during mitosis and
                     meiosis, intragenic recombination, repair of double strand
                     DNA breaks, and DNA replication during nucleotide excision
                     repair (NER)"
                     /codon_start=1
                     /product="DNA-directed DNA polymerase delta POL3"
                     /protein_id="NP_010181.2"
                     /db_xref="GI:330443503"
                     /db_xref="SGD:S000002260"
                     /db_xref="GeneID:851456"
                     /translation="MSEKRSLPMVDVKIDDEDTPQLEKKIKRQSIDHGVGSEPVSTIE
                     IIPSDSFRKYNSQGFKAKDTDLMGTQLESTFEQELSQMEHDMADQEEHDLSSFERKKL
                     PTDFDPSLYDISFQQIDAEQSVLNGIKDENTSTVVRFFGVTSEGHSVLCNVTGFKNYL
                     YVPAPNSSDANDQEQINKFVHYLNETFDHAIDSIEVVSKQSIWGYSGDTKLPFWKIYV
                     TYPHMVNKLRTAFERGHLSFNSWFSNGTTTYDNIAYTLRLMVDCGIVGMSWITLPKGK
                     YSMIEPNNRVSSCQLEVSINYRNLIAHPAEGDWSHTAPLRIMSFDIECAGRIGVFPEP
                     EYDPVIQIANVVSIAGAKKPFIRNVFTLNTCSPITGSMIFSHATEEEMLSNWRNFIIK
                     VDPDVIIGYNTTNFDIPYLLNRAKALKVNDFPYFGRLKTVKQEIKESVFSSKAYGTRE
                     TKNVNIDGRLQLDLLQFIQREYKLRSYTLNAVSAHFLGEQKEDVHYSIISDLQNGDSE
                     TRRRLAVYCLKDAYLPLRLMEKLMALVNYTEMARVTGVPFSYLLARGQQIKVVSQLFR
                     KCLEIDTVIPNMQSQASDDQYEGATVIEPIRGYYDVPIATLDFNSLYPSIMMAHNLCY
                     TTLCNKATVERLNLKIDEDYVITPNGDYFVTTKRRRGILPIILDELISARKRAKKDLR
                     DEKDPFKRDVLNGRQLALKISANSVYGFTGATVGKLPCLAISSSVTAYGRTMILKTKT
                     AVQEKYCIKNGYKHDAVVVYGDTDSVMVKFGTTDLKEAMDLGTEAAKYVSTLFKHPIN
                     LEFEKAYFPYLLINKKRYAGLFWTNPDKFDKLDQKGLASVRRDSCSLVSIVMNKVLKK
                     ILIERNVDGALAFVRETINDILHNRVDISKLIISKTLAPNYTNPQPHAVLAERMKRRE
                     GVGPNVGDRVDYVIIGGNDKLYNRAEDPLFVLENNIQVDSRYYLTNQLQNPIISIVAP
                     IIGDKQANGMFVVKSIKINTGSQKGGLMSFIKKVEACKSCKGPLRKGEGPLCSNCLAR
                     SGELYIKALYDVRDLEEKYSRLWTQCQRCAGNLHSEVLCSNKNCDIFYMRVKVKKELQ
                     EKVEQLSKW"
     gene            complement(<280307..>281848)
                     /gene="DUN1"
                     /locus_tag="YDL101C"
                     /db_xref="GeneID:851457"
     mRNA            complement(<280307..>281848)
                     /gene="DUN1"
                     /locus_tag="YDL101C"
                     /product="Dun1p"
                     /transcript_id="NM_001180160.1"
                     /db_xref="GI:296143267"
                     /db_xref="GeneID:851457"
     CDS             complement(280307..281848)
                     /gene="DUN1"
                     /locus_tag="YDL101C"
                     /EC_number="2.7.11.1"
                     /note="Cell-cycle checkpoint serine-threonine kinase;
                     required for DNA damage-induced transcription of certain
                     target genes, phosphorylation of Rad55p and Sml1p, and
                     transient G2/M arrest after DNA damage; Mec1p and Dun1p
                     function in same pathway to regulate both dNTP pools and
                     telomere length; also regulates postreplicative DNA
                     repair"
                     /codon_start=1
                     /product="Dun1p"
                     /protein_id="NP_010182.1"
                     /db_xref="GI:6320102"
                     /db_xref="SGD:S000002259"
                     /db_xref="GeneID:851457"
                     /translation="MSLSTKREHSGDVTDSSFKRQQRSNKPSSEYTCLGHLVNLIPGK
                     EQKVEITNRNVTTIGRSRSCDVILSEPDISTFHAEFHLLQMDVDNFQRNLINVIDKSR
                     NGTFINGNRLVKKDYILKNGDRIVFGKSCSFLFKYASSSSTDIENDDEKVSSESRSYK
                     NDDEVFKKPQISATSSQNATTSAAIRKLNKTRPVSFFDKYLLGKELGAGHYALVKEAK
                     NKKTGQQVAVKIFHAQQNDDQKKNKQFREETNILMRVQHPNIVNLLDSFVEPISKSQI
                     QKYLVLEKIDDGELFERIVRKTCLRQDESKALFKQLLTGLKYLHEQNIIHRDIKPENI
                     LLNITRRENPSQVQLGPWDEDEIDIQVKIADFGLAKFTGEMQFTNTLCGTPSYVAPEV
                     LTKKGYTSKVDLWSAGVILYVCLCGFPPFSDQLGPPSLKEQILQAKYAFYSPYWDKID
                     DSVLHLISNLLVLNPDERYNIDEALNHPWFNDIQQQSSVSLELQRLQITDNKIPKTYS
                     ELSCL"
     gene            complement(<282112..>283176)
                     /gene="GET3"
                     /locus_tag="YDL100C"
                     /gene_synonym="ARR4"
                     /db_xref="GeneID:851458"
     mRNA            complement(<282112..>283176)
                     /gene="GET3"
                     /locus_tag="YDL100C"
                     /gene_synonym="ARR4"
                     /product="guanine nucleotide exchange factor GET3"
                     /transcript_id="NM_001180159.1"
                     /db_xref="GI:296143268"
                     /db_xref="GeneID:851458"
     CDS             complement(282112..283176)
                     /gene="GET3"
                     /locus_tag="YDL100C"
                     /gene_synonym="ARR4"
                     /EC_number="3.6.-.-"
                     /note="Guanine nucleotide exchange factor for Gpa1p;
                     amplifies G protein signaling; subunit of the GET complex,
                     which is involved in Golgi to ER trafficking and insertion
                     of proteins into the ER membrane; has low-level ATPase
                     activity; protein abundance increases in response to DNA
                     replication stress"
                     /codon_start=1
                     /product="guanine nucleotide exchange factor GET3"
                     /protein_id="NP_010183.1"
                     /db_xref="GI:6320103"
                     /db_xref="SGD:S000002258"
                     /db_xref="GeneID:851458"
                     /translation="MDLTVEPNLHSLITSTTHKWIFVGGKGGVGKTTSSCSIAIQMAL
                     SQPNKQFLLISTDPAHNLSDAFGEKFGKDARKVTGMNNLSCMEIDPSAALKDMNDMAV
                     SRANNNGSDGQGDDLGSLLQGGALADLTGSIPGIDEALSFMEVMKHIKRQEQGEGETF
                     DTVIFDTAPTGHTLRFLQLPNTLSKLLEKFGEITNKLGPMLNSFMGAGNVDISGKLNE
                     LKANVETIRQQFTDPDLTTFVCVCISEFLSLYETERLIQELISYDMDVNSIIVNQLLF
                     AENDQEHNCKRCQARWKMQKKYLDQIDELYEDFHVVKMPLCAGEIRGLNNLTKFSQFL
                     NKEYNPITDGKVIYELEDKE"
     gene            <283419..>284444
                     /gene="BUG1"
                     /locus_tag="YDL099W"
                     /db_xref="GeneID:851459"
     mRNA            <283419..>284444
                     /gene="BUG1"
                     /locus_tag="YDL099W"
                     /product="Bug1p"
                     /transcript_id="NM_001180158.1"
                     /db_xref="GI:296143269"
                     /db_xref="GeneID:851459"
     CDS             283419..284444
                     /gene="BUG1"
                     /locus_tag="YDL099W"
                     /note="Cis-golgi localized protein involved in ER to Golgi
                     transport; forms a complex with the mammalian GRASP65
                     homolog, Grh1p; mutants are compromised for the fusion of
                     ER-derived vesicles with Golgi membranes"
                     /codon_start=1
                     /product="Bug1p"
                     /protein_id="NP_010184.1"
                     /db_xref="GI:6320104"
                     /db_xref="SGD:S000002257"
                     /db_xref="GeneID:851459"
                     /translation="MSEQESDEVKRMKQLEEARKRVEELKKKKNKKNKGKKNKNSSAT
                     GSIGSETPDLEGTPGEESTQEETVKANSTKSENNDQNDVDEESEEKEIEQVKSDPSGT
                     TEKDIEEINSTSSNVGKDDAENTKKEEVQEVIKNNNDEQTADAGKTIEPQEEKKIVQT
                     QEGNEPSNTSEAADDLFANDGNEESDFLTTIKKQKEEDELTKLRAENEKLTQENKQLK
                     FLNMENETTVDDLQDQLQEKEDIINGLQNDLQTARDELIAAVEKLKLAEAKAARNTTA
                     TPIQFADFNTSSNNLTPSQSVTNSGTQVAHGNNMEVDRVMLNKWRQWNVDMTTWRSIG
                     SGPIMEF"
     gene            complement(<284581..>285165)
                     /gene="SNU23"
                     /locus_tag="YDL098C"
                     /db_xref="GeneID:851460"
     mRNA            complement(<284581..>285165)
                     /gene="SNU23"
                     /locus_tag="YDL098C"
                     /product="Snu23p"
                     /transcript_id="NM_001180157.1"
                     /db_xref="GI:296143270"
                     /db_xref="GeneID:851460"
     CDS             complement(284581..285165)
                     /gene="SNU23"
                     /locus_tag="YDL098C"
                     /note="Component of the U4/U6.U5 snRNP complex; involved
                     in mRNA splicing via spliceosome"
                     /codon_start=1
                     /product="Snu23p"
                     /protein_id="NP_010185.1"
                     /db_xref="GI:6320105"
                     /db_xref="SGD:S000002256"
                     /db_xref="GeneID:851460"
                     /translation="MSNFGRRTWDREEYAEQARSGYDDRSLKATLTPIELQALKSKYT
                     NYDHLIKGSLKDLNKRKLTANTESLSSFKRGKKFGFYCDICNLTFKDTLQYIDHLNHK
                     VHAIKFENLFDEPLIIDIRDNDDVPQEEFELCYHNLIKDFVEVRSMETQSKRKRLLDT
                     DVEKAKKVATKPSIESESKVSQMMGFSNFATSKK"
     gene            complement(<285391..>286695)
                     /gene="RPN6"
                     /locus_tag="YDL097C"
                     /gene_synonym="NAS4"
                     /db_xref="GeneID:851461"
     mRNA            complement(<285391..>286695)
                     /gene="RPN6"
                     /locus_tag="YDL097C"
                     /gene_synonym="NAS4"
                     /product="proteasome regulatory particle lid subunit RPN6"
                     /transcript_id="NM_001180156.1"
                     /db_xref="GI:296143271"
                     /db_xref="GeneID:851461"
     CDS             complement(285391..286695)
                     /gene="RPN6"
                     /locus_tag="YDL097C"
                     /gene_synonym="NAS4"
                     /note="Essential, non-ATPase regulatory subunit of the 26S
                     proteasome lid; required for the assembly and activity of
                     the 26S proteasome; the human homolog (S9 protein)
                     partially rescues Rpn6p depletion; protein abundance
                     increases in response to DNA replication stress"
                     /codon_start=1
                     /product="proteasome regulatory particle lid subunit RPN6"
                     /protein_id="NP_010186.1"
                     /db_xref="GI:6320106"
                     /db_xref="SGD:S000002255"
                     /db_xref="GeneID:851461"
                     /translation="MSLPGSKLEEARRLVNEKQYNEAEQVYLSLLDKDSSQSSAAAGA
                     SVDDKRRNEQETSILELGQLYVTMGAKDKLREFIPHSTEYMMQFAKSKTVKVLKTLIE
                     KFEQVPDSLDDQIFVCEKSIEFAKREKRVFLKHSLSIKLATLHYQKKQYKDSLALIND
                     LLREFKKLDDKPSLVDVHLLESKVYHKLRNLAKSKASLTAARTAANSIYCPTQTVAEL
                     DLMSGILHCEDKDYKTAFSYFFESFESYHNLTTHNSYEKACQVLKYMLLSKIMLNLID
                     DVKNILNAKYTKETYQSRGIDAMKAVAEAYNNRSLLDFNTALKQYEKELMGDELTRSH
                     FNALYDTLLESNLCKIIEPFECVEISHISKIIGLDTQQVEGKLSQMILDKIFYGVLDQ
                     GNGWLYVYETPNQDATYDSALELVGQLNKVVDQLFEKASVLY"
     gene            <287059..>289512
                     /gene="PMT1"
                     /locus_tag="YDL095W"
                     /db_xref="GeneID:851462"
     mRNA            <287059..>289512
                     /gene="PMT1"
                     /locus_tag="YDL095W"
                     /product="Pmt1p"
                     /transcript_id="NM_001180154.1"
                     /db_xref="GI:296143272"
                     /db_xref="GeneID:851462"
     CDS             287059..289512
                     /gene="PMT1"
                     /locus_tag="YDL095W"
                     /EC_number="2.4.1.109"
                     /note="Protein O-mannosyltransferase of the ER membrane;
                     transfers mannose from dolichyl phosphate-D-mannose to
                     protein serine and threonine residues; 1 of 7 related
                     proteins involved in O-glycosylation which is essential
                     for cell wall rigidity; involved in ER quality control;
                     amino terminus faces cytoplasm, carboxyl terminus faces ER
                     lumen"
                     /codon_start=1
                     /product="Pmt1p"
                     /protein_id="NP_010188.1"
                     /db_xref="GI:6320107"
                     /db_xref="SGD:S000002253"
                     /db_xref="GeneID:851462"
                     /translation="MSEEKTYKRVEQDDPVPELDIKQGPVRPFIVTDPSAELASLRTM
                     VTLKEKLLVACLAVFTAVIRLHGLAWPDSVVFDEVHFGGFASQYIRGTYFMDVHPPLA
                     KMLYAGVASLGGFQGDFDFENIGDSFPSTTPYVLMRFFSASLGALTVILMYMTLRYSG
                     VRMWVALMSAICFAVENSYVTISRYILLDAPLMFFIAAAVYSFKKYEMYPANSLNAYK
                     SLLATGIALGMASSSKWVGLFTVTWVGLLCIWRLWFMIGDLTKSSKSIFKVAFAKLAF
                     LLGVPFALYLVFFYIHFQSLTLDGDGASFFSPEFRSTLKNNKIPQNVVADVGIGSIIS
                     LRHLSTMGGYLHSHSHNYPAGSEQQQSTLYPHMDANNDWLLELYNAPGESLTTFQNLT
                     DGTKVRLFHTVTRCRLHSHDHKPPVSESSDWQKEVSCYGYSGFDGDANDDWVVEIDKK
                     NSAPGVAQERVIALDTKFRLRHAMTGCYLFSHEVKLPAWGFEQQEVTCASSGRHDLTL
                     WYVENNSNPLLPEDTKRISYKPASFISKFIESHKKMWHINKNLVEPHVYESQPTSWPF
                     LLRGISYWGENNRNVYLLGNAIVWWAVTAFIGIFGLIVITELFSWQLGKPILKDSKVV
                     NFHVQVIHYLLGFAVHYAPSFLMQRQMFLHHYLPAYYFGILALGHALDIIVSYVFRSK
                     RQMGYAVVITFLAASVYFFKSFSPIIYGTPWTQELCQKSQWLSGWDYNCNTYFSSLEE
                     YKNQTLTKRESQPAATSTVEEITIEGDGPSYEDLMNEDGKKIFKDTEGNELDPEVVKK
                     MLEEEGANILKVEKRAVLE"
     gene            <289909..>292140
                     /gene="PMT5"
                     /locus_tag="YDL093W"
                     /db_xref="GeneID:851464"
     mRNA            <289909..>292140
                     /gene="PMT5"
                     /locus_tag="YDL093W"
                     /product="Pmt5p"
                     /transcript_id="NM_001180152.1"
                     /db_xref="GI:296143273"
                     /db_xref="GeneID:851464"
     CDS             289909..292140
                     /gene="PMT5"
                     /locus_tag="YDL093W"
                     /EC_number="2.4.1.109"
                     /note="Protein O-mannosyltransferase; transfers mannose
                     residues from dolichyl phosphate-D-mannose to protein
                     serine/threonine residues; acts in a complex with Pmt3p,
                     can instead interact with Pmt2p in some conditions; target
                     for new antifungals"
                     /codon_start=1
                     /product="Pmt5p"
                     /protein_id="NP_010190.1"
                     /db_xref="GI:6320109"
                     /db_xref="SGD:S000002251"
                     /db_xref="GeneID:851464"
                     /translation="MNKEHLLKVDPIPDVTIKRGPLRSFLITKPCDNLSSLRTVTSSK
                     EKLLVGCLLIFTAIVRLHNISLPNSVVFGENEVGTFVSQYVNNIFFTDVHPPLVAMLY
                     ATVSSVFGYKGLFNYGNIGTEYTANVPYVAMRFFSATLGIVSVLVLYLTLRVSGVKIA
                     VAAICAVCFAIENSFVTLSRFTLIEGPFVFFMACAVYFFRRSELYLPNSCKANKSLLA
                     ASIALGFAVSSKWAGLFTIAWAGIIVLWRVWFMIGDLSRPIGSSIKYMAFQFTCLLAI
                     PAFIYFLIFSVHIKTLNVNGISSSFFPAEFRKTLKYNNVIKETVAEVAVGSAVSLNHV
                     GTAGGYLHSHLHNYPAGSMQQQVTLYPHIDQNNKWIIELAEHPNENVTSFQNLTDGTI
                     IKLRQLKNGCRLHSHDHKPPVSQNADWQKEVSCYGYEGFEGDINDDWIIEIDKKRSEP
                     GPAQEHIRAIETKFRLKHYLTGCYLFSHPEKLPEWGFGQQEVTCAYFAREDLTSWYIE
                     ENENEISLPNPEKVSYKKMSFWQKFVAIHKFMFYLNNYMDTSHAYSSEPKTWPLMLRG
                     IDFWNENGREVYFLGNAVLWWSVTAFICTFIIGVAVELLAWKLGVNILRDKHIINFHY
                     QVFQYLLGFAAHYFPYFFVGQKLFLYDYLPAYYFGILAFGHALDLISTYISNKRNNTG
                     YIVVAIFMVVCFYFFSEHSPLIYATGWSSNLCKRSKWLGSWDFYCNSLLLSDSHYELN
                     AES"
     gene            <292781..>293221
                     /gene="SRP14"
                     /locus_tag="YDL092W"
                     /db_xref="GeneID:851466"
     mRNA            <292781..>293221
                     /gene="SRP14"
                     /locus_tag="YDL092W"
                     /product="Srp14p"
                     /transcript_id="NM_001180151.1"
                     /db_xref="GI:296143274"
                     /db_xref="GeneID:851466"
     CDS             292781..293221
                     /gene="SRP14"
                     /locus_tag="YDL092W"
                     /note="Signal recognition particle (SRP) subunit;
                     interacts with the RNA component of SRP to form the Alu
                     domain, which is the region of SRP responsible for arrest
                     of nascent chain elongation during membrane targeting;
                     homolog of mammalian SRP14"
                     /codon_start=1
                     /product="Srp14p"
                     /protein_id="NP_010191.1"
                     /db_xref="GI:6320111"
                     /db_xref="SGD:S000002250"
                     /db_xref="GeneID:851466"
                     /translation="MANTGCLSPGAFLSKVPEFFQTANEKHITVRLTAKRLIEHDPVE
                     GNLEFDSTNHPDYDVSKKASEISVSSRSDREYPLLIRMSYGSHDKKTKCSTVVKASEL
                     DQFWQEYSSVFKGGMQNLIKKKKKKSKNGTISKTGKKNKVAKKN"
     gene            complement(<293392..>294759)
                     /gene="UBX3"
                     /locus_tag="YDL091C"
                     /db_xref="GeneID:851467"
     mRNA            complement(<293392..>294759)
                     /gene="UBX3"
                     /locus_tag="YDL091C"
                     /product="Ubx3p"
                     /transcript_id="NM_001180150.1"
                     /db_xref="GI:296143275"
                     /db_xref="GeneID:851467"
     CDS             complement(293392..294759)
                     /gene="UBX3"
                     /locus_tag="YDL091C"
                     /note="Subunit of the DSC ubiquitin ligase complex; UBX
                     (ubiquitin regulatory X) domain-containing protein that
                     interacts with Cdc48p; green fluorescent protein
                     (GFP)-fusion protein localizes to the cytoplasm in a
                     punctate pattern; ortholog of fission yeast Ucp10"
                     /codon_start=1
                     /product="Ubx3p"
                     /protein_id="NP_010192.1"
                     /db_xref="GI:6320112"
                     /db_xref="SGD:S000002249"
                     /db_xref="GeneID:851467"
                     /translation="MDIFRHTFGNNDDSFIRIPGAFREEPPADLNGRTEDQNSNTNEP
                     TQSRDGRLKSILHFLFQAPLIVLYYLLNFIVRSSRLLKPLLRLHGFYQRKHNRLLDHS
                     SQLHRLLENLENEAQAVTCSEGNGNNDDGSNTDSTSNNESSGVQFSFGSLYNPENGTF
                     SKSIMQNSYTELLDACSEQVKFGVIYLHDPLLDNHMDYVNKILCSEAFVNMIRKYQVL
                     LWYGDVTTSEGLQVSNALKIRQYPLLGIISLKAEKKIELIARVEGSISNYKAQDLEAI
                     FSKNYSRLIQLRQQRQNIEMQRLIRQQQDSRYQDSLRRDQQRESERLEQTQREQMERE
                     HQRIENQWLLWRKSQLKPEPSSDKDASKVAIRLENGQRLVRKFDASLPTEEIYAFVEL
                     QLHDMLNSENDTLPVYQPANYQHQYSFKLITPVPRRELDLSTKISDVSGIYPSGNIVM
                     ERLDE"
     gene            complement(<295034..>296329)
                     /gene="RAM1"
                     /locus_tag="YDL090C"
                     /gene_synonym="DPR1; FUS8; SCG2; SGP2; STE16"
                     /db_xref="GeneID:851468"
     mRNA            complement(<295034..>296329)
                     /gene="RAM1"
                     /locus_tag="YDL090C"
                     /gene_synonym="DPR1; FUS8; SCG2; SGP2; STE16"
                     /product="protein farnesyltransferase"
                     /transcript_id="NM_001180149.1"
                     /db_xref="GI:296143276"
                     /db_xref="GeneID:851468"
     CDS             complement(295034..296329)
                     /gene="RAM1"
                     /locus_tag="YDL090C"
                     /gene_synonym="DPR1; FUS8; SCG2; SGP2; STE16"
                     /EC_number="2.5.1.58"
                     /note="Beta subunit of the CAAX farnesyltransferase
                     (FTase); this complex prenylates the a-factor mating
                     pheromone and Ras proteins; required for the membrane
                     localization of Ras proteins and a-factor; homolog of the
                     mammalian FTase beta subunit"
                     /codon_start=1
                     /product="protein farnesyltransferase"
                     /protein_id="NP_010193.1"
                     /db_xref="GI:6320113"
                     /db_xref="SGD:S000002248"
                     /db_xref="GeneID:851468"
                     /translation="MRQRVGRSIARAKFINTALLGRKRPVMERVVDIAHVDSSKAIQP
                     LMKELETDTTEARYKVLQSVLEIYDDEKNIEPALTKEFHKMYLDVAFEISLPPQMTAL
                     DASQPWMLYWIANSLKVMDRDWLSDDTKRKIVDKLFTISPSGGPFGGGPGQLSHLAST
                     YAAINALSLCDNIDGCWDRIDRKGIYQWLISLKEPNGGFKTCLEVGEVDTRGIYCALS
                     IATLLNILTEELTEGVLNYLKNCQNYEGGFGSCPHVDEAHGGYTFCATASLAILRSMD
                     QINVEKLLEWSSARQLQEERGFCGRSNKLVDGCYSFWVGGSAAILEAFGYGQCFNKHA
                     LRDYILYCCQEKEQPGLRDKPGAHSDFYHTNYCLLGLAVAESSYSCTPNDSPHNIKCT
                     PDRLIGSSKLTDVNPVYGLPIENVRKIIHYFKSNLSSPS"
     gene            <296820..>298274
                     /gene="NUR1"
                     /locus_tag="YDL089W"
                     /db_xref="GeneID:851469"
     mRNA            <296820..>298274
                     /gene="NUR1"
                     /locus_tag="YDL089W"
                     /product="Nur1p"
                     /transcript_id="NM_001180148.1"
                     /db_xref="GI:296143277"
                     /db_xref="GeneID:851469"
     CDS             296820..298274
                     /gene="NUR1"
                     /locus_tag="YDL089W"
                     /note="hypothetical protein; interacts with Csm1p, Lrs4p;
                     required for rDNA repeat stability; null mutant causes
                     increase in unequal sister-chromatid exchange; GFP-fusion
                     protein localizes to the nuclear periphery, possible
                     Cdc28p substrate"
                     /codon_start=1
                     /product="Nur1p"
                     /protein_id="NP_010194.1"
                     /db_xref="GI:6320114"
                     /db_xref="SGD:S000002247"
                     /db_xref="GeneID:851469"
                     /translation="MGSNDLINEAYDDSEVVGEERESKSAWMKRWYQLLTSPLDLQLV
                     INEKLEMINWDAYAKSLAKPLGNFLTILFFIIRLLQDNLIKPNYYKLNVKSGAFDLSK
                     SNKLKEFDYLWEISSSFQNNNQFYAFQSWYFVTLRFLNNLFRFTIFILLSLNLYVSCK
                     FMFGYFKTYNLFHLKKEFNSPNLTKHNLKDLSKEYYEDIYKQSLWSMLKHFFRGSRDD
                     GPHVNQNEDEIFFQLRKWIPTNFMINLFVSFSPTAIVFLSFSDVSFTSAIAIVFHQYI
                     LDYIITKRFQRSVDDDLILSSAALQEYEDKHIMARINQCSNIDTLSSAMGTRSKTPRI
                     FTTHSLCGEEIREVYNYEKREFEALPKMTESVPGSRETRIKDYGGISQVSDHQSHPIG
                     FHYSPRMSPYYRDKVLDNNLAQSSSNENLEKGGAYLPNQDQNRPSKSLSPLRKTPLSA
                     RQKRFEGSEFNVLNKNDINSILRSPKKKKNYHKR"
     gene            complement(<298417..>300003)
                     /gene="ASM4"
                     /locus_tag="YDL088C"
                     /gene_synonym="NUP59"
                     /db_xref="GeneID:851470"
     mRNA            complement(<298417..>300003)
                     /gene="ASM4"
                     /locus_tag="YDL088C"
                     /gene_synonym="NUP59"
                     /product="Asm4p"
                     /transcript_id="NM_001180147.1"
                     /db_xref="GI:296143278"
                     /db_xref="GeneID:851470"
     CDS             complement(298417..300003)
                     /gene="ASM4"
                     /locus_tag="YDL088C"
                     /gene_synonym="NUP59"
                     /note="FG-nucleoporin component of central core of nuclear
                     pore complex (NPC); contributes directly to
                     nucleocytoplasmic transport; induces membrane tubulation,
                     which may contribute to nuclear pore assembly; ASM4 has a
                     paralog, NUP53, that arose from the whole genome
                     duplication"
                     /codon_start=1
                     /product="Asm4p"
                     /protein_id="NP_010195.1"
                     /db_xref="GI:6320115"
                     /db_xref="SGD:S000002246"
                     /db_xref="GeneID:851470"
                     /translation="MFGIRSGNNNGGFTNLTSQAPQTTQMFQSQSQLQPQPQPQPQQQ
                     QQHLQFNGSSDASSLRFGNSLSNTVNANNYSSNIGNNSINNNNIKNGTNNISQHGQGN
                     NPSWVNNPKKRFTPHTVIRRKTTKQNSSSDINQNDDSSSMNATMRNFSKQNQDSKHNE
                     RNKSAANNDINSLLSNFNDIPPSVTLQDWQREDEFGSIPSLTTQFVTDKYTAKKTNRS
                     AYDSKNTPNVFDKDSYVRIANIEQNHLDNNYNTAETNNKVHETSSKSSSLSAIIVFGY
                     PESISNELIEHFSHFGHIMEDFQVLRLGRGINPNTFRIFHNHDTGCDENDSTVNKSIT
                     LKGRNNESNNKKYPIFTGESWVKLTYNSPSSALRALQENGTIFRGSLIGCIPYSKNAV
                     EQLAGCKIDNVDDIGEFNVSMYQNSSTSSTSNTPSPPNVIITDGTLLREDDNTPAGHA
                     GNPTNISSPIVANSPNKRLDVIDGKLPFMQNAGPNSNIPNLLRNLESKMRQQEAKYRN
                     NEPAGFTHKLSNWLFGWNDL"
     gene            complement(<300214..>300999)
                     /gene="LUC7"
                     /locus_tag="YDL087C"
                     /gene_synonym="EPE1; EXM2"
                     /db_xref="GeneID:851471"
     mRNA            complement(<300214..>300999)
                     /gene="LUC7"
                     /locus_tag="YDL087C"
                     /gene_synonym="EPE1; EXM2"
                     /product="Luc7p"
                     /transcript_id="NM_001180146.1"
                     /db_xref="GI:296143279"
                     /db_xref="GeneID:851471"
     CDS             complement(300214..300999)
                     /gene="LUC7"
                     /locus_tag="YDL087C"
                     /gene_synonym="EPE1; EXM2"
                     /note="Essential protein associated with the U1 snRNP
                     complex; splicing factor involved in recognition of 5'
                     splice site; contains two zinc finger motifs; N-terminal
                     zinc finger binds pre-mRNA; relocalizes to the cytosol in
                     response to hypoxia"
                     /codon_start=1
                     /product="Luc7p"
                     /protein_id="NP_010196.1"
                     /db_xref="GI:6320116"
                     /db_xref="SGD:S000002245"
                     /db_xref="GeneID:851471"
                     /translation="MSTMSTPAAEQRKLVEQLMGRDFSFRHNRYSHQKRDLGLHDPKI
                     CKSYLVGECPYDLFQGTKQSLGKCPQMHLTKHKIQYEREVKQGKTFPEFEREYLAILS
                     RFVNECNGQISVALQNLKHTAEERMKIQQVTEELDVLDVRIGLMGQEIDSLIRADEVS
                     MGMLQSVKLQELISKRKEVAKRVRNITENVGQSAQQKLQVCEVCGAYLSRLDTDRRLA
                     DHFLGKIHLGYVKMREDYDRLMKNNRTTNASKTATTLPGRRFV"
     gene            <301413..>302234
                     /locus_tag="YDL086W"
                     /db_xref="GeneID:851472"
     mRNA            <301413..>302234
                     /locus_tag="YDL086W"
                     /product="carboxymethylenebutenolidase"
                     /transcript_id="NM_001180145.1"
                     /db_xref="GI:296143280"
                     /db_xref="GeneID:851472"
     CDS             301413..302234
                     /locus_tag="YDL086W"
                     /EC_number="3.1.1.45"
                     /note="Putative carboxymethylenebutenolidase; the
                     authentic, non-tagged protein is detected in highly
                     purified mitochondria in high-throughput studies; YDL086W
                     is not an essential gene"
                     /codon_start=1
                     /product="carboxymethylenebutenolidase"
                     /protein_id="NP_010197.1"
                     /db_xref="GI:6320117"
                     /db_xref="SGD:S000002244"
                     /db_xref="GeneID:851472"
                     /translation="MLITETFHDVQTSYGTTLRIYVYSPKIAGYPQAKFPGVILYSEI
                     YQVTGPVRRFGQRIASEGYVVVAPAIYHNFMGPEALPYDVQGTDIGNEYKIKKPLESY
                     DEDNKLCCDLLFQLPQFDGKRIGSTGMCLGGHLAFRALLDKRVTCATCFFPTDIHSRT
                     LGLGQNDNSLERVSKELGNNQEMVLIFGTADTHVDPQGRDLIRKTLRDHGVKFTFLEI
                     LAAQHAFIRDEFSKGRFDSAITQSCLGFLFEQFNRKLRIDLGEFVDDNTPLEHVC"
     gene            complement(<302464..>302670)
                     /locus_tag="YDL085C-A"
                     /db_xref="GeneID:851473"
     mRNA            complement(<302464..>302670)
                     /locus_tag="YDL085C-A"
                     /product="hypothetical protein"
                     /transcript_id="NM_001184455.1"
                     /db_xref="GI:296143281"
                     /db_xref="GeneID:851473"
     CDS             complement(302464..302670)
                     /locus_tag="YDL085C-A"
                     /note="hypothetical protein; green fluorescent protein
                     (GFP)-fusion protein localizes to the cytoplasm and
                     nucleus"
                     /codon_start=1
                     /product="hypothetical protein"
                     /protein_id="NP_075208.1"
                     /db_xref="GI:12621478"
                     /db_xref="SGD:S000007588"
                     /db_xref="GeneID:851473"
                     /translation="MARGNQRDLARQKNLKKQKDMAKNQKKSGDPKKRMESDAEILRQ
                     KQAAADARREAEKLEKLKAEKTRR"
     gene            <303211..>304848
                     /gene="NDE2"
                     /locus_tag="YDL085W"
                     /gene_synonym="NDH2"
                     /db_xref="GeneID:851474"
     mRNA            <303211..>304848
                     /gene="NDE2"
                     /locus_tag="YDL085W"
                     /gene_synonym="NDH2"
                     /product="NADH-ubiquinone reductase (H(+)-translocating)
                     NDE2"
                     /transcript_id="NM_001180144.1"
                     /db_xref="GI:296143282"
                     /db_xref="GeneID:851474"
     CDS             303211..304848
                     /gene="NDE2"
                     /locus_tag="YDL085W"
                     /gene_synonym="NDH2"
                     /EC_number="1.6.5.9"
                     /EC_number="1.6.5.3"
                     /note="Mitochondrial external NADH dehydrogenase;
                     catalyzes the oxidation of cytosolic NADH; Nde1p and Nde2p
                     are involved in providing the cytosolic NADH to the
                     mitochondrial respiratory chain; NDE2 has a paralog, NDE1,
                     that arose from the whole genome duplication"
                     /codon_start=1
                     /product="NADH-ubiquinone reductase (H(+)-translocating)
                     NDE2"
                     /protein_id="NP_010198.1"
                     /db_xref="GI:6320118"
                     /db_xref="SGD:S000002243"
                     /db_xref="GeneID:851474"
                     /translation="MLPRLGFARTARSIHRFKMTQISKPFFHSTEVGKPGPQQKLSKS
                     YTAVFKKWFVRGLKLTFYTTLAGTLYVSYELYKESNPPKQVPQSTAFANGLKKKELVI
                     LGTGWGAISLLKKLDTSLYNVTVVSPRSFFLFTPLLPSTPVGTIEMKSIVEPVRSIAR
                     RTPGEVHYIEAEALDVDPKAKKVMVQSVSEDEYFVSSLSYDYLVVSVGAKTTTFNIPG
                     VYGNANFLKEIEDAQNIRMKLMKTIEQASSFPVNDPERKRLLTFVVVGGGPTGVEFAA
                     ELQDYINQDLRKWMPDLSKEMKVILIEALPNILNMFDKTLIKYAEDLFARDEIDLQVN
                     TAVKVVEPTYIRTLQNGQTNTDIEYGMLVWATGNEPIDFSKTLMSRIPEQTNRRGLLI
                     NDKLELLGSENSIYAIGDCTAHTGFFPTAQVAHQEGEYLAKILDKKLQIEQLEWDMLN
                     STDETEVSRLQKEVNLRKSKLDKFNYKHMGALAYIGSETAIADLHMGDSSYQLKGMFA
                     FLFWKSAYLAMCLSIRNRILIAMDWTKVYFLGRDSSV"
     gene            <305237..>306577
                     /gene="SUB2"
                     /locus_tag="YDL084W"
                     /db_xref="GeneID:851475"
     mRNA            <305237..>306577
                     /gene="SUB2"
                     /locus_tag="YDL084W"
                     /product="ATP-dependent RNA helicase SUB2"
                     /transcript_id="NM_001180143.1"
                     /db_xref="GI:296143283"
                     /db_xref="GeneID:851475"
     CDS             305237..306577
                     /gene="SUB2"
                     /locus_tag="YDL084W"
                     /EC_number="3.6.4.13"
                     /note="Component of the TREX complex required for nuclear
                     mRNA export; member of the DEAD-box RNA helicase
                     superfamily and is involved in early and late steps of
                     spliceosome assembly; homolog of the human splicing factor
                     hUAP56; relocalizes from nucleus to cytoplasm upon DNA
                     replication stress"
                     /codon_start=1
                     /product="ATP-dependent RNA helicase SUB2"
                     /protein_id="NP_010199.1"
                     /db_xref="GI:6320119"
                     /db_xref="SGD:S000002242"
                     /db_xref="GeneID:851475"
                     /translation="MSHEGEEDLLEYSDNEQEIQIDASKAAEAGETGAATSATEGDNN
                     NNTAAGDKKGSYVGIHSTGFKDFLLKPELSRAIIDCGFEHPSEVQQHTIPQSIHGTDV
                     LCQAKSGLGKTAVFVLSTLQQLDPVPGEVAVVVICNARELAYQIRNEYLRFSKYMPDV
                     KTAVFYGGTPISKDAELLKNKDTAPHIVVATPGRLKALVREKYIDLSHVKNFVIDECD
                     KVLEELDMRRDVQEIFRATPRDKQVMMFSATLSQEIRPICRRFLQNPLEIFVDDEAKL
                     TLHGLQQYYIKLEEREKNRKLAQLLDDLEFNQVIIFVKSTTRANELTKLLNASNFPAI
                     TVHGHMKQEERIARYKAFKDFEKRICVSTDVFGRGIDIERINLAINYDLTNEADQYLH
                     RVGRAGRFGTKGLAISFVSSKEDEEVLAKIQERFDVKIAEFPEEGIDPSTYLNN"
     gene            complement(<306926..>307789)
                     /gene="RPS16B"
                     /locus_tag="YDL083C"
                     /db_xref="GeneID:851476"
     mRNA            complement(join(<306926..307333,307766..>307789))
                     /gene="RPS16B"
                     /locus_tag="YDL083C"
                     /product="ribosomal 40S subunit protein S16B"
                     /transcript_id="NM_001180142.1"
                     /db_xref="GI:296143284"
                     /db_xref="GeneID:851476"
     CDS             complement(join(306926..307333,307766..307789))
                     /gene="RPS16B"
                     /locus_tag="YDL083C"
                     /note="Protein component of the small (40S) ribosomal
                     subunit; homologous to mammalian ribosomal protein S16 and
                     bacterial S9; RPS16B has a paralog, RPS16A, that arose
                     from the whole genome duplication"
                     /codon_start=1
                     /product="ribosomal 40S subunit protein S16B"
                     /protein_id="NP_010200.1"
                     /db_xref="GI:6320120"
                     /db_xref="SGD:S000002241"
                     /db_xref="GeneID:851476"
                     /translation="MSAVPSVQTFGKKKSATAVAHVKAGKGLIKVNGSPITLVEPEIL
                     RFKVYEPLLLVGLDKFSNIDIRVRVTGGGHVSQVYAIRQAIAKGLVAYHQKYVDEQSK
                     NELKKAFTSYDRTLLIADSRRPEPKKFGGKGARSRFQKSYR"
     gene            <308424..>309388
                     /gene="RPL13A"
                     /locus_tag="YDL082W"
                     /db_xref="GeneID:851477"
     mRNA            join(<308424..308427,308793..>309388)
                     /gene="RPL13A"
                     /locus_tag="YDL082W"
                     /product="ribosomal 60S subunit protein L13A"
                     /transcript_id="NM_001180141.1"
                     /db_xref="GI:296143285"
                     /db_xref="GeneID:851477"
     CDS             join(308424..308427,308793..309388)
                     /gene="RPL13A"
                     /locus_tag="YDL082W"
                     /note="Ribosomal 60S subunit protein L13A; not essential
                     for viability; homologous to mammalian ribosomal protein
                     L13, no bacterial homolog; RPL13A has a paralog, RPL13B,
                     that arose from the whole genome duplication"
                     /codon_start=1
                     /product="ribosomal 60S subunit protein L13A"
                     /protein_id="NP_010201.1"
                     /db_xref="GI:6320121"
                     /db_xref="SGD:S000002240"
                     /db_xref="GeneID:851477"
                     /translation="MAISKNLPILKNHFRKHWQERVKVHFDQAGKKVSRRNARATRAA
                     KIAPRPLDLLRPVVRAPTVKYNRKVRAGRGFTLAEVKAAGLTAAYARTIGIAVDHRRQ
                     NRNQEIFDANVQRLKEYQSKIIVFPRNGKAPEAEQVLSAAATFPIAQPATDVEARAVQ
                     DNGESAFRTLRLARSEKKFRGIREKRAREKAEAEAEKKK"
     gene            complement(<309802..>310122)
                     /gene="RPP1A"
                     /locus_tag="YDL081C"
                     /gene_synonym="RPLA1"
                     /db_xref="GeneID:851478"
     mRNA            complement(<309802..>310122)
                     /gene="RPP1A"
                     /locus_tag="YDL081C"
                     /gene_synonym="RPLA1"
                     /product="ribosomal protein P1A"
                     /transcript_id="NM_001180140.1"
                     /db_xref="GI:296143286"
                     /db_xref="GeneID:851478"
     CDS             complement(309802..310122)
                     /gene="RPP1A"
                     /locus_tag="YDL081C"
                     /gene_synonym="RPLA1"
                     /note="Ribosomal stalk protein P1 alpha; involved in the
                     interaction between translational elongation factors and
                     the ribosome; free (non-ribosomal) P1 stimulates the
                     phosphorylation of the eIF2 alpha subunit (Sui2p) by
                     Gcn2p; accumulation of P1 in the cytoplasm is regulated by
                     phosphorylation and interaction with the P2 stalk
                     component"
                     /codon_start=1
                     /product="ribosomal protein P1A"
                     /protein_id="NP_010202.1"
                     /db_xref="GI:6320122"
                     /db_xref="SGD:S000002239"
                     /db_xref="GeneID:851478"
                     /translation="MSTESALSYAALILADSEIEISSEKLLTLTNAANVPVENIWADI
                     FAKALDGQNLKDLLVNFSAGAAAPAGVAGGVAGGEAGEAEAEKEEEEAKEESDDDMGF
                     GLFD"
     gene            complement(<310642..>312471)
                     /gene="THI3"
                     /locus_tag="YDL080C"
                     /gene_synonym="KID1"
                     /db_xref="GeneID:851479"
     mRNA            complement(<310642..>312471)
                     /gene="THI3"
                     /locus_tag="YDL080C"
                     /gene_synonym="KID1"
                     /product="branched-chain-2-oxoacid decarboxylase THI3"
                     /transcript_id="NM_001180139.1"
                     /db_xref="GI:296143287"
                     /db_xref="GeneID:851479"
     CDS             complement(310642..312471)
                     /gene="THI3"
                     /locus_tag="YDL080C"
                     /gene_synonym="KID1"
                     /EC_number="4.1.1.-"
                     /note="Regulatory protein that binds Pdc2p and Thi2p
                     transcription factors; activates thiamine biosynthesis
                     transcription factors Pdc2p and Thi2p by binding to them,
                     but releases and de-activates them upon binding to
                     thiamine pyrophosphate (TPP), the end product of the
                     pathway; has similarity to decarboxylases but enzymatic
                     activity is not detected"
                     /codon_start=1
                     /product="branched-chain-2-oxoacid decarboxylase THI3"
                     /protein_id="NP_010203.1"
                     /db_xref="GI:6320123"
                     /db_xref="SGD:S000002238"
                     /db_xref="GeneID:851479"
                     /translation="MNSSYTQRYALPKCIAISDYLFHRLNQLNIHTIFGLSGEFSMPL
                     LDKLYNIPNLRWAGNSNELNAAYAADGYSRLKGLGCLITTFGVGELSAINGVAGSYAE
                     HVGILHIVGMPPTSAQTKQLLLHHTLGNGDFTVFHRIASDVACYTTLIIDSELCADEV
                     DKCIKKAWIEQRPVYMGMPVNQVNLPIESARLNTPLDLQLHKNDPDVEKEVISRILSF
                     IYKSQNPAIIVDACTSRQNLIEETKELCNRLKFPVFVTPMGKGTVNETDPQFGGVFTG
                     SISAPEVREVVDFADFIIVIGCMLSEFSTSTFHFQYKTKNCALLYSTSVKLKNATYPD
                     LSIKLLLQKILANLDESKLSYQPSEQPSMMVPRPYPAGNVLLRQEWVWNEISHWFQPG
                     DIIITETGASAFGVNQTRFPVNTLGISQALWGSVGYTMGACLGAEFAVQEINKDKFPA
                     TKHRVILFMGDGAFQLTVQELSTIVKWGLTPYIFVMNNQGYSVDRFLHHRSDASYYDI
                     QPWNYLGLLRVFGCTNYETKKIITVGEFRSMISDPNFATNDKIRMIEIMLPPRDVPQA
                     LLDRWVVEKEQSKQVQEENENSSAVNTPTPEFQPLLKKNQVGY"
     gene            complement(<312951..>314748)
                     /gene="MRK1"
                     /locus_tag="YDL079C"
                     /db_xref="GeneID:851480"
     mRNA            complement(join(<312951..314044,314337..>314748))
                     /gene="MRK1"
                     /locus_tag="YDL079C"
                     /product="Mrk1p"
                     /transcript_id="NM_001180138.1"
                     /db_xref="GI:296143288"
                     /db_xref="GeneID:851480"
     CDS             complement(join(312951..314044,314337..314748))
                     /gene="MRK1"
                     /locus_tag="YDL079C"
                     /EC_number="2.7.11.1"
                     /note="Glycogen synthase kinase 3 (GSK-3) homolog; one of
                     four GSK-3 homologs in S. cerevisiae that function to
                     activate Msn2p-dependent transcription of stress
                     responsive genes and that function in protein degradation;
                     MRK1 has a paralog, RIM11, that arose from the whole
                     genome duplication"
                     /codon_start=1
                     /product="Mrk1p"
                     /protein_id="NP_010204.1"
                     /db_xref="GI:6320124"
                     /db_xref="SGD:S000002237"
                     /db_xref="GeneID:851480"
                     /translation="MTDVLRSLVRKISFNNSDNLQLKHKTSIQSNTALEKKKRKPDTI
                     KKVSDVQVHHTVPNFNNSSEYINDIENLIISKLIDGGKEGIAVDHIEHANISDSKTDG
                     KVANKHENISSKLSKEKVEKMINFDYRYIKTKERTIHKRVYKHDRKTDVDRKNHGGTI
                     DISYPTTEVVGHGSFGVVVTTVIIETNQKVAIKKVLQDRRYKNRELETMKMLCHPNTV
                     GLQYYFYEKDEEDEVYLNLVLDYMPQSLYQRLRHFVNLKMQMPRVEIKFYAYQLFKAL
                     NYLHNVPRICHRDIKPQNLLVDPTTFSFKICDFGSAKCLKPDQPNVSYICSRYYRAPE
                     LMFGATNYSNQVDVWSSACVIAELLLGKPLFSGESGIDQLVEIIKIMGIPTKDEISGM
                     NPNYEDHVFPNIKPITLAEIFKAEDPDTLDLLTKTLKYHPCERLVPLQCLLSSYFDET
                     KRCDTDTYVKAQNLRIFDFDVETELGHVPLVERPAIEERLKHFVSAPSSSL"
     gene            complement(<315357..>316388)
                     /gene="MDH3"
                     /locus_tag="YDL078C"
                     /db_xref="GeneID:851481"
     mRNA            complement(<315357..>316388)
                     /gene="MDH3"
                     /locus_tag="YDL078C"
                     /product="malate dehydrogenase MDH3"
                     /transcript_id="NM_001180137.1"
                     /db_xref="GI:296143289"
                     /db_xref="GeneID:851481"
     CDS             complement(315357..316388)
                     /gene="MDH3"
                     /locus_tag="YDL078C"
                     /EC_number="1.1.1.37"
                     /note="Peroxisomal malate dehydrogenase; catalyzes
                     interconversion of malate and oxaloacetate; involved in
                     the glyoxylate cycle"
                     /codon_start=1
                     /product="malate dehydrogenase MDH3"
                     /protein_id="NP_010205.1"
                     /db_xref="GI:6320125"
                     /db_xref="SGD:S000002236"
                     /db_xref="GeneID:851481"
                     /translation="MVKVAILGASGGVGQPLSLLLKLSPYVSELALYDIRAAEGIGKD
                     LSHINTNSSCVGYDKDSIENTLSNAQVVLIPAGVPRKPGLTRDDLFKMNAGIVKSLVT
                     AVGKFAPNARILVISNPVNSLVPIAVETLKKMGKFKPGNVMGVTNLDLVRAETFLVDY
                     LMLKNPKIGQEQDKTTMHRKVTVIGGHSGETIIPIITDKSLVFQLDKQYEHFIHRVQF
                     GGDEIVKAKQGAGSATLSMAFAGAKFAEEVLRSFHNEKPETESLSAFVYLPGLKNGKK
                     AQQLVGDNSIEYFSLPIVLRNGSVVSIDTSVLEKLSPREEQLVNTAVKELRKNIEKGK
                     SFILDSSKL"
     rep_origin      316388..316971
                     /note="ARS412;
                     Putative replication origin; identified in multiple array
                     studies, not yet confirmed by plasmid-based assay"
                     /db_xref="SGD:S000130172"
     gene            complement(<316971..>320120)
                     /gene="VAM6"
                     /locus_tag="YDL077C"
                     /gene_synonym="CVT4; VPL18; VPL22; VPS39"
                     /db_xref="GeneID:851482"
     mRNA            complement(<316971..>320120)
                     /gene="VAM6"
                     /locus_tag="YDL077C"
                     /gene_synonym="CVT4; VPL18; VPL22; VPS39"
                     /product="Vam6p"
                     /transcript_id="NM_001180136.1"
                     /db_xref="GI:296143290"
                     /db_xref="GeneID:851482"
     CDS             complement(316971..320120)
                     /gene="VAM6"
                     /locus_tag="YDL077C"
                     /gene_synonym="CVT4; VPL18; VPL22; VPS39"
                     /note="Vacuolar protein involved in vacuolar membrane
                     fusion tethering; plays a critical role in the tethering
                     steps of vacuolar membrane fusion by facilitating guanine
                     nucleotide exchange on small guanosine triphosphatase
                     Ypt7p"
                     /codon_start=1
                     /product="Vam6p"
                     /protein_id="NP_010206.1"
                     /db_xref="GI:6320126"
                     /db_xref="SGD:S000002235"
                     /db_xref="GeneID:851482"
                     /translation="MLRAQKLHSLKSSDITAILPTEQSQKLVLAKKNGDVEVYSRDGN
                     TLKLFQVYPDLLQNAKNDPLPPVIENFYFANELSTIFAQCKETLILLSTTNLHEYDRI
                     IDRRGINHCWLFERSHKNKEEKNTYLIYSTINTAKMRVLIWEGRTYKNMMEASLSYRK
                     ETIRSIYPGETGITLATDLGIYHWPYNKPSLIRIEKTVKNKFPKDMISALTELKEQAE
                     KVIEKKPKKNSHFDAQSFSSMDRMSRKSSMSSLWYRTIRNERGNKIRYTFELDGNDAT
                     PMIIDGATKKIFKVELMHNNEEPFLIATDHATFSESNSEFDHMQYLSSNLLMLYNSST
                     IKFVDYENGFTFLQQKIPEGIKWVKNLSGTYFLVWTSNDEVQLFSYHVDDGSEDDDQE
                     SICGDINDPDFYQLWRKVLFYKFFIDSPHSKELCVSDNPEESLDICAMKLRDLTVMWC
                     LRIFDKFQNYMVQLERSRNSRMIRSKCEEMIIKSIFDLFIKFWAPPQLVILKVFPSAI
                     SSLVLEITGQEHHCLLKEAEEVKETYDIPPHLLNRWCLPYLTDTRRHLQNLLSKENDD
                     ESRITWCYRDREIKQSFDFFLISNHDDVDLNTMLTLIDTVLFKCYLYYNPPMVGPFIR
                     VENHCDSHVIVTELKIRHMFKDLIDFYYKRGNHEEALKFLTDLVDELENDNTDQKQRQ
                     KIDHGVKILVIYYLKKLSNPQLDVIFTYTDWLLNRHNDSIKEILSSIFFYDSQACSSR
                     DHLKVYGYIKKFDKLLAIQYLEFAISTFRLEGNKLHTVLIKLYLENLDIPSTRIKLKS
                     LLETTSVYEPRTILKLLNDAIESGSDQLPTNQLNFVKYLKIFPLSKLENHKEAVHILL
                     DEIDDYKAATSYCNDVYQSDSTKGEELLLYLYSKLVSIYDSNRNSKLILNFLQDHGSK
                     LNSAEIYKNLPQDISLYDIGRVVSQLLKKHTSKMDETRLEKALLQVELVATTYKLNER
                     MSSYGVLSDSHKCPICKKVISNFGTDSISWFTREGRNIITHYNCGKVLQERFNAKNEK
                     SSRIKQKTLGEVINELNNK"
     gene            complement(<320668..>321552)
                     /gene="RXT3"
                     /locus_tag="YDL076C"
                     /db_xref="GeneID:851483"
     mRNA            complement(<320668..>321552)
                     /gene="RXT3"
                     /locus_tag="YDL076C"
                     /product="Rxt3p"
                     /transcript_id="NM_001180135.1"
                     /db_xref="GI:296143291"
                     /db_xref="GeneID:851483"
     CDS             complement(320668..321552)
                     /gene="RXT3"
                     /locus_tag="YDL076C"
                     /note="Component of the Rpd3L histone deacetylase complex;
                     involved in histone deacetylation; protein abundance
                     increases in response to DNA replication stress"
                     /codon_start=1
                     /product="Rxt3p"
                     /protein_id="NP_010207.1"
                     /db_xref="GI:6320127"
                     /db_xref="SGD:S000002234"
                     /db_xref="GeneID:851483"
                     /translation="MSVSEQDPNRAYRETQSQIYKLQETLLNSARTKNKQEEGQESNT
                     HSFPEQYMHYQNGRNSAYDLPNVSSQSVLAFTEKHYPNKLKNLGTLYYNRFKEGSFDE
                     DSTSYSDRHSFPYNLYDNTLPPPFLPAIGIQNINNIATLKITYEDIQASFNNIESPRK
                     RNNEIWGCDIYSDDSDPILVLRHCGFKIGAPSGGSFHKLRRTPVNVTNQDNVTGNLPL
                     LEGTPFDLEVELLFLPTLQKYPSVKRFDITSREWGSEATVIHDGLSYGIYSIVIKQRL
                     DRDKPHEPNGYIKNLKWT"
     gene            <322226..>322988
                     /gene="RPL31A"
                     /locus_tag="YDL075W"
                     /gene_synonym="RPL34"
                     /db_xref="GeneID:851484"
     mRNA            join(<322226..322282,322704..>322988)
                     /gene="RPL31A"
                     /locus_tag="YDL075W"
                     /gene_synonym="RPL34"
                     /product="ribosomal 60S subunit protein L31A"
                     /transcript_id="NM_001180134.1"
                     /db_xref="GI:296143292"
                     /db_xref="GeneID:851484"
     CDS             join(322226..322282,322704..322988)
                     /gene="RPL31A"
                     /locus_tag="YDL075W"
                     /gene_synonym="RPL34"
                     /note="Ribosomal 60S subunit protein L31A; associates with
                     karyopherin Sxm1p; loss of both Rpl31p and Rpl39p confers
                     lethality; homologous to mammalian ribosomal protein L31,
                     no bacterial homolog; RPL31A has a paralog, RPL31B, that
                     arose from the whole genome duplication"
                     /codon_start=1
                     /product="ribosomal 60S subunit protein L31A"
                     /protein_id="NP_010208.1"
                     /db_xref="GI:6320128"
                     /db_xref="SGD:S000002233"
                     /db_xref="GeneID:851484"
                     /translation="MAGLKDVVTREYTINLHKRLHGVSFKKRAPRAVKEIKKFAKLHM
                     GTDDVRLAPELNQAIWKRGVKGVEYRLRLRISRKRNEEEDAKNPLFSYVEPVLVASAK
                     GLQTVVVEEDA"
     gene            complement(323217..323471)
                     /locus_tag="snR63"
                     /db_xref="GeneID:9164876"
     ncRNA           complement(323217..323471)
                     /locus_tag="snR63"
                     /ncRNA_class="snoRNA"
                     /product="SNR63"
                     /note="C/D box small nucleolar RNA (snoRNA); guides
                     2'-O-methylation of large subunit (LSU) rRNA at position
                     A2256"
                     /db_xref="SGD:S000006454"
                     /db_xref="GeneID:9164876"
     gene            complement(<324047..>326149)
                     /gene="BRE1"
                     /locus_tag="YDL074C"
                     /db_xref="GeneID:851485"
     mRNA            complement(<324047..>326149)
                     /gene="BRE1"
                     /locus_tag="YDL074C"
                     /product="E3 ubiquitin-protein ligase BRE1"
                     /transcript_id="NM_001180133.1"
                     /db_xref="GI:296143293"
                     /db_xref="GeneID:851485"
     CDS             complement(324047..326149)
                     /gene="BRE1"
                     /locus_tag="YDL074C"
                     /EC_number="6.3.2.-"
                     /note="E3 ubiquitin ligase; forms heterodimer with Rad6p
                     to monoubiquinate histone H2B-K123, which is required for
                     the subsequent methylation of histone H3-K4 and H3-K79;
                     required for DSBR, transcription, silencing, and
                     checkpoint control; interacts with RNA-binding protein
                     Npl3p, linking histone ubiquitination to mRNA processing;
                     Bre1p-dependent histone ubiquitination promotes pre-mRNA
                     splicing"
                     /codon_start=1
                     /product="E3 ubiquitin-protein ligase BRE1"
                     /protein_id="NP_010209.1"
                     /db_xref="GI:6320129"
                     /db_xref="SGD:S000002232"
                     /db_xref="GeneID:851485"
                     /translation="MTAEPATKKIKLELSDPSEPLTQSDVIAFQKEALFRCINRRRVD
                     FEALRKQYELSRRECIDVSRKLANIMALIVTLARFIETFCTDANEKQLCREIAQGDET
                     LIVQRSDSFMKLLTKYGKPNTTDSNTNSNASDHIQELTTELKNLRKSKEELFYENSQL
                     TEEISALKEYYTNIIRKYDRDESFTIKRVFKEDKTDAVKELREDEKESNENNIKSGNK
                     DSSAINGDNTSKKSEKGDELVQAEDERKEDAENEKLELDLKFSDLRAEINSLSSTIKD
                     LENIRRENEEELIKTRSEVSNLKKQQIAAADQDPDFKSYDHESLLAKIQHLTEQNAEL
                     SEINSSFLSKFQVLAKEKEIYTKKVREEFQKSLDSLVEMNSSLEKDVVRIRTARDDLL
                     SKIAILEAEKSKTEVLSDLQHAIDILKEQWTKIDQRSNDTKSSSTQDALIKEIQDLEK
                     GFRELSDLTHKKYSEIINHESVISKLTVEKTKADQKYFAAMRSKDSILIEIKTLSKSL
                     SKSNELILQLKDSDRLLQQKIGNLHKQLDLSQNNERRLIDSSKTETLKIIDLNNTSTK
                     LKRSLEKLQEESNKSIADMTHLETKLNDTEIELKHFKQKASHLESKCEKLHDTLFRGN
                     NKNKGSSDEALVEELANFRTLVYCSLCSKNWKNMAIKTCGHVFCENCCKERLAARMRK
                     CPTCNKAFSSNDLLTVHL"
     gene            <326613..>329567
                     /locus_tag="YDL073W"
                     /db_xref="GeneID:851486"
     mRNA            <326613..>329567
                     /locus_tag="YDL073W"
                     /product="hypothetical protein"
                     /transcript_id="NM_001180132.1"
                     /db_xref="GI:296143294"
                     /db_xref="GeneID:851486"
     CDS             326613..329567
                     /locus_tag="YDL073W"
                     /note="hypothetical protein; YDL073W is not an essential
                     gene"
                     /codon_start=1
                     /product="hypothetical protein"
                     /protein_id="NP_010210.1"
                     /db_xref="GI:6320130"
                     /db_xref="SGD:S000002231"
                     /db_xref="GeneID:851486"
                     /translation="MGPAIHNQLYECGLKTTSQDGFLMDNYETQLFQSLNRFINFINN
                     ANQSASNKEQNTKFCKSSSNFLRLKLLTVLRQWCDSSRSNCTLEVRDVLTQWWVTLLN
                     FLNSDTSLQIDTALELSLSIELTSVCLECLSKIMTILIILPFHSSRDMEIYSHHLLLT
                     IHCITNKLILISKNSKKLKRTNSDDKCSINDKKLQYLNKYSSLLRAFIGKLNAYAFFY
                     LPEDFHFDTILLLTVSPQISSSIQTSLFSWKKRQYKFTDDQGQMIRTEAFENKDTKFF
                     KIIVSYIKNDFVLMSFYWHYWYIILQFMKFSDSDVGIKKSTLSCIPGSEILLTHVTTR
                     FLNSDLNKFTRIIKQTPNPRIANENVTESHPNFKSLNSSNALITSERINDYVFSNFKT
                     IKLWECLRSLSGCILKENHPEYLENMLSLHESLLIDYVSTISAYDYIAANVIYNKVLQ
                     FIIFQFESLPSLKFIQWRSWYNGLLSMLRTKNVNCQTVSLLCLFNIWKHVTIEDRDEI
                     VKVLLSDFWESLIFENEFPLIRILFMKVLVFKIIPSVQNSSSLRFLPHDRIKQLYEEL
                     LVNKEELFEMQKHDSNDIVAHRKNALVFNGNSRLMMIPKKPNTEDHLVYKINHDKNLT
                     TERFPSVSSVANTRPNVILKNGKYAYDILDEMTSKAAFLLAEKKTRLNPKKNHKIMDG
                     YEGGQENEDNDEDSEDSGSHKNKRKEGNSSLSATLNTWLSKFSSTSEDSQKKKEQANE
                     LGNDFEYDEDVADFAEILPKQSSSNIEKIFKHGNNSGSMVSYNSSIKLNRRENILIGP
                     PELRFSNEIKEHNSIATIFKLVFIQTNRRVVEKIDLANMKWGTIHGGSKYMKPLPVPK
                     DLVASVAKNESETRNLATLCGNGLDFEIPVPDFNIFGKCMEDEQDVAKIGNQNVEDLK
                     VTGGREVTIWKQIQDMKLRTRIQKICVLIETFNATVREYFEFSNRLEHDGIFIDFEVR
                     KPSSNNSINIKV"
     rep_origin      329566..329814
                     /note="ARS413;
                     Autonomously Replicating Sequence"
                     /db_xref="SGD:S000118432"
     gene            complement(<329836..>330447)
                     /gene="YET3"
                     /locus_tag="YDL072C"
                     /db_xref="GeneID:851487"
     mRNA            complement(<329836..>330447)
                     /gene="YET3"
                     /locus_tag="YDL072C"
                     /product="Yet3p"
                     /transcript_id="NM_001180131.1"
                     /db_xref="GI:296143295"
                     /db_xref="GeneID:851487"
     CDS             complement(329836..330447)
                     /gene="YET3"
                     /locus_tag="YDL072C"
                     /note="hypothetical protein; YET3 null mutant decreases
                     the level of secreted invertase; homolog of human BAP31
                     protein; protein abundance increases in response to DNA
                     replication stress"
                     /codon_start=1
                     /product="Yet3p"
                     /protein_id="NP_010211.1"
                     /db_xref="GI:6320131"
                     /db_xref="SGD:S000002230"
                     /db_xref="GeneID:851487"
                     /translation="MSLYYTLVFAILVVEIFMFSILALPIPSRYRRPLTLLLLKPFKS
                     STVQVAIKCVLGFILLLFIDCINRVYSIDKELQLSSASQNNGAIIAQDRIEVLSRKFF
                     AQRNMYLTGITLFLTFVVVRTFGLVIELLTMKDIYRASPPVASSDVKKNDSVTAEAAA
                     QSGASKDDHGDEKNFELLKKIQDIDDEIARLKEKSESLQEEIN"
     gene            <331024..>332940
                     /gene="BDF2"
                     /locus_tag="YDL070W"
                     /db_xref="GeneID:851488"
     mRNA            <331024..>332940
                     /gene="BDF2"
                     /locus_tag="YDL070W"
                     /product="Bdf2p"
                     /transcript_id="NM_001180129.1"
                     /db_xref="GI:296143296"
                     /db_xref="GeneID:851488"
     CDS             331024..332940
                     /gene="BDF2"
                     /locus_tag="YDL070W"
                     /note="Protein involved in transcription initiation; acts
                     at TATA-containing promoters; associates with the basal
                     transcription factor TFIID; contains two bromodomains;
                     corresponds to the C-terminal region of mammalian TAF1;
                     redundant with Bdf1p; protein abundance increases in
                     response to DNA replication stress; BDF2 has a paralog,
                     BDF1, that arose from the whole genome duplication"
                     /codon_start=1
                     /product="Bdf2p"
                     /protein_id="NP_010213.1"
                     /db_xref="GI:6320132"
                     /db_xref="SGD:S000002228"
                     /db_xref="GeneID:851488"
                     /translation="MSRTNMDTRHAHSALLAAPQSATANSRSSNSSSESSSNKNNINV
                     GVGDDSGNVSAVSIDDGPHFRDIFHYGHEENYKLASSGITNLNSSSHAHQTLSPISIS
                     NASTPESFPEHPLGLERETEPALEAEMEAEELPPHQSKYLLSSIKATKRLKDARPFLK
                     PVDPIALNIPHYFNYVQTPMDLSLIETKLQGNVYHSVEQVTSDFKTMVDNCLNFNGPE
                     SSISSMAKRIQKYFEKKLSAMPPRVLPASALKKTSRNRKKNEDMDSPLVIRRSVSTTN
                     DNIGESGNREGVSGGRPKRTIHPPKSKDLFDIYENSKPKSKTLQKKFRTCLKILKVLM
                     SKKNSDINFPFLQPVDPIALNLPNYFDVVKNPMDLGTISNNLMNWKYKTIDQFVDDLN
                     LVFYNCFQFNPEGNEVHSMGKKLKELFNFHWLENQDILNEIETDSDLEEDNYSSSYSS
                     DDEYDDEDINENDITNPAIQYLEQKLKKMEVELQQLKRQELSKLSKERKRKHLGKTLL
                     RRKAMKHSVDDLKKSITDKINELSDLEMNGMIRIIKNSLPADEILTSNEDEIEIDLDI
                     LDEATIARIYERYFEKKNNNNSKRKLSGNYSTAPTNKKKKTLKFLEKDEIINNNNYSD
                     SEEDSSDSSDSDSD"
     gene            complement(<333121..>333810)
                     /gene="CBS1"
                     /locus_tag="YDL069C"
                     /db_xref="GeneID:851491"
     mRNA            complement(<333121..>333810)
                     /gene="CBS1"
                     /locus_tag="YDL069C"
                     /product="Cbs1p"
                     /transcript_id="NM_001180128.1"
                     /db_xref="GI:296143297"
                     /db_xref="GeneID:851491"
     CDS             complement(333121..333810)
                     /gene="CBS1"
                     /locus_tag="YDL069C"
                     /note="Mitochondrial translational activator of the COB
                     mRNA; membrane protein that interacts with translating
                     ribosomes, acts on the COB mRNA 5'-untranslated leader"
                     /codon_start=1
                     /product="Cbs1p"
                     /protein_id="NP_010214.2"
                     /db_xref="GI:37362630"
                     /db_xref="SGD:S000002227"
                     /db_xref="GeneID:851491"
                     /translation="MLRTKVFATTVARISGIRRYIPIRTINTVTKKNISKIEKLCEVL
                     EVNPDGYKGKERIPTKELTKLLYTTSRNMLVRVPMTGDLSTGNTFETRNETLQKLGEQ
                     LIHLEINKMLTITFTNFNQFNIMNKNFNYIHNLDRARVVNMDSISWLIKNSLKINQLA
                     HLRIPANLPKEMGLTSSSNDFQNLNDWKVILSFIGYLKLLEIKNDNKKFIESIIKTIC
                     IPLINYHLRKS"
     gene            complement(<334217..>334396)
                     /gene="COX9"
                     /locus_tag="YDL067C"
                     /db_xref="GeneID:851492"
     mRNA            complement(<334217..>334396)
                     /gene="COX9"
                     /locus_tag="YDL067C"
                     /product="cytochrome c oxidase subunit VIIa"
                     /transcript_id="NM_001180126.1"
                     /db_xref="GI:296143298"
                     /db_xref="GeneID:851492"
     CDS             complement(334217..334396)
                     /gene="COX9"
                     /locus_tag="YDL067C"
                     /EC_number="1.9.3.1"
                     /note="Subunit VIIa of cytochrome c oxidase (Complex IV);
                     Complex IV is the terminal member of the mitochondrial
                     inner membrane electron transport chain"
                     /codon_start=1
                     /product="cytochrome c oxidase subunit VIIa"
                     /protein_id="NP_010216.1"
                     /db_xref="GI:6320136"
                     /db_xref="SGD:S000002225"
                     /db_xref="GeneID:851492"
                     /translation="MTIAPITGTIKRRVIMDIVLGFSLGGVMASYWWWGFHMDKINKR
                     EKFYAELAERKKQEN"
     gene            <334835..>336121
                     /gene="IDP1"
                     /locus_tag="YDL066W"
                     /db_xref="GeneID:851493"
     mRNA            <334835..>336121
                     /gene="IDP1"
                     /locus_tag="YDL066W"
                     /product="isocitrate dehydrogenase (NADP(+)) IDP1"
                     /transcript_id="NM_001180125.1"
                     /db_xref="GI:296143299"
                     /db_xref="GeneID:851493"
     CDS             334835..336121
                     /gene="IDP1"
                     /locus_tag="YDL066W"
                     /EC_number="1.1.1.42"
                     /note="Mitochondrial NADP-specific isocitrate
                     dehydrogenase; catalyzes the oxidation of isocitrate to
                     alpha-ketoglutarate; not required for mitochondrial
                     respiration and may function to divert alpha-ketoglutarate
                     to biosynthetic processes"
                     /codon_start=1
                     /product="isocitrate dehydrogenase (NADP(+)) IDP1"
                     /protein_id="NP_010217.1"
                     /db_xref="GI:6320137"
                     /db_xref="SGD:S000002224"
                     /db_xref="GeneID:851493"
                     /translation="MSMLSRRLFSTSRLAAFSKIKVKQPVVELDGDEMTRIIWDKIKK
                     KLILPYLDVDLKYYDLSVESRDATSDKITQDAAEAIKKYGVGIKCATITPDEARVKEF
                     NLHKMWKSPNGTIRNILGGTVFREPIVIPRIPRLVPRWEKPIIIGRHAHGDQYKATDT
                     LIPGPGSLELVYKPSDPTTAQPQTLKVYDYKGSGVAMAMYNTDESIEGFAHSSFKLAI
                     DKKLNLFLSTKNTILKKYDGRFKDIFQEVYEAQYKSKFEQLGIHYEHRLIDDMVAQMI
                     KSKGGFIMALKNYDGDVQSDIVAQGFGSLGLMTSILVTPDGKTFESEAAHGTVTRHYR
                     KYQKGEETSTNSIASIFAWSRGLLKRGELDNTPALCKFANILESATLNTVQQDGIMTK
                     DLALACGNNERSAYVTTEEFLDAVEKRLQKEIKSIE"
     gene            complement(<336249..>337277)
                     /gene="PEX19"
                     /locus_tag="YDL065C"
                     /gene_synonym="PAS12"
                     /db_xref="GeneID:851494"
     mRNA            complement(<336249..>337277)
                     /gene="PEX19"
                     /locus_tag="YDL065C"
                     /gene_synonym="PAS12"
                     /product="Pex19p"
                     /transcript_id="NM_001180124.1"
                     /db_xref="GI:296143300"
                     /db_xref="GeneID:851494"
     CDS             complement(336249..337277)
                     /gene="PEX19"
                     /locus_tag="YDL065C"
                     /gene_synonym="PAS12"
                     /note="Chaperone and import receptor for newly-synthesized
                     class I PMPs; binds peroxisomal membrane proteins (PMPs)
                     in the cytoplasm and delivers them to the peroxisome for
                     subsequent insertion into the peroxisomal membrane;
                     interacts with Myo2p and contributes to peroxisome
                     partitioning"
                     /codon_start=1
                     /product="Pex19p"
                     /protein_id="NP_010218.2"
                     /db_xref="GI:93117371"
                     /db_xref="SGD:S000002223"
                     /db_xref="GeneID:851494"
                     /translation="MNENEYDNFDDLDDLLDEDPTKLDEAEPDDVQAKGSVYNDSENK
                     EKNAESKDSDGVQVANESEEDPELKEMMVDLQNEFANLMKNNGNENNVKTEDFNKLIS
                     ALEEAAKVPHQQMEQGCSSLKSNSTDKGTVNGSNPGFKNIVSNTLDRLKENGNKVDTS
                     LAEETKESQRSGQNNNIDDILSQLLDQMVASGGKESAENQFDLKDGEMDDAITKILDQ
                     MTSKEVLYEPMKEMRSEFGVWFQENGENEEHKEKIGTYKRQFNIVDEIVNIYELKDYD
                     ELKHKDRVTELLDELEQLGDSPIRSANSPLKHGNEEEELMKMLEIDGNDPNLGNLDKE
                     LTDGCKQQ"
     gene            <337487..>338070
                     /gene="UBC9"
                     /locus_tag="YDL064W"
                     /db_xref="GeneID:851495"
     mRNA            join(<337487..337524,337635..>338070)
                     /gene="UBC9"
                     /locus_tag="YDL064W"
                     /product="E2 SUMO-conjugating protein UBC9"
                     /transcript_id="NM_001180123.1"
                     /db_xref="GI:296143301"
                     /db_xref="GeneID:851495"
     CDS             join(337487..337524,337635..338070)
                     /gene="UBC9"
                     /locus_tag="YDL064W"
                     /EC_number="6.3.2.-"
                     /note="SUMO-conjugating enzyme involved in the Smt3p
                     conjugation pathway; nuclear protein required for S- and
                     M-phase cyclin degradation and mitotic control; involved
                     in proteolysis mediated by the anaphase-promoting complex
                     cyclosome (APCC)"
                     /codon_start=1
                     /product="E2 SUMO-conjugating protein UBC9"
                     /protein_id="NP_010219.1"
                     /db_xref="GI:6320139"
                     /db_xref="SGD:S000002222"
                     /db_xref="GeneID:851495"
                     /translation="MSSLCLQRLQEERKKWRKDHPFGFYAKPVKKADGSMDLQKWEAG
                     IPGKEGTNWAGGVYPITVEYPNEYPSKPPKVKFPAGFYHPNVYPSGTICLSILNEDQD
                     WRPAITLKQIVLGVQDLLDSPNPNSPAQEPAWRSFSRNKAEYDKKVLLQAKQYSK"
     gene            complement(<338272..>340134)
                     /gene="SYO1"
                     /locus_tag="YDL063C"
                     /db_xref="GeneID:851497"
     mRNA            complement(<338272..>340134)
                     /gene="SYO1"
                     /locus_tag="YDL063C"
                     /product="Syo1p"
                     /transcript_id="NM_001180122.1"
                     /db_xref="GI:296143302"
                     /db_xref="GeneID:851497"
     CDS             complement(338272..340134)
                     /gene="SYO1"
                     /locus_tag="YDL063C"
                     /note="Transport adaptor or symportin; facilitates
                     synchronized nuclear coimport of the two 5S-rRNA binding
                     proteins Rpl5p and Rpl11p; required for biogenesis of the
                     large ribosomal subunit; green fluorescent protein
                     (GFP)-fusion protein localizes to the cytoplasm and
                     nucleus"
                     /codon_start=1
                     /product="Syo1p"
                     /protein_id="NP_010220.1"
                     /db_xref="GI:6320141"
                     /db_xref="SGD:S000002221"
                     /db_xref="GeneID:851497"
                     /translation="MGRSKKRSRASSSRLNPLRKAGSNDNNKDTNVVNKKLQPLLQNL
                     SSVVPNDRSIALSSISVLCEDAHMRQLLLKEKLVPIILNKLLNDSNSDIVVESFGLLR
                     NLSLEEGYDVSIYLWRSDIWTSITSNFGRIVESLSALQAAEQQPQLKPAGKSKIESKR
                     LLFDFADNLLSLVVALSNGSDDILNEILTESKINEIFQVISQLLKYGVEKLPINLFNT
                     TLDLIYDLSSESFEFIDHVSNNELLSQFLNGLSPALHPQANELTKVLIEGIHCQFLDM
                     KITYDQCNKMIHSVCHSINNIDPVQLVNDINNPVEIGPATSKDESSKVITKIKDYNAK
                     RNESMIKLQSIEIAIDLITAIIEIVASKYESPESQEVAIPEELINTLTNFLPHVFMIL
                     KDTFTSRILIGWNNLIWLFVSLSLTELSGELLTTLWSYVTQLDSQDDLSIKIGRMGCI
                     WALLKLIFPDGAFESENRALINVQMLNNSGFARGIIEEFQNNNDLELQQKCINVLSTY
                     AMIQGQIDANKEIGQFFIQTLTQLNVRPEILIEMTNSLFQIYGDASYDYNEPIFVRGG
                     FLSILKDQVVPNLRQQFKMVDKNKNPELKERCHDCFTTLDSFIHYKMNENSTNQ"
     gene            complement(<340628..>340798)
                     /gene="RPS29B"
                     /locus_tag="YDL061C"
                     /db_xref="GeneID:851498"
     mRNA            complement(<340628..>340798)
                     /gene="RPS29B"
                     /locus_tag="YDL061C"
                     /product="ribosomal 40S subunit protein S29B"
                     /transcript_id="NM_001180120.1"
                     /db_xref="GI:296143303"
                     /db_xref="GeneID:851498"
     CDS             complement(340628..340798)
                     /gene="RPS29B"
                     /locus_tag="YDL061C"
                     /note="Protein component of the small (40S) ribosomal
                     subunit; homologous to mammalian ribosomal protein S29 and
                     bacterial S14; RPS29B has a paralog, RPS29A, that arose
                     from the whole genome duplication"
                     /codon_start=1
                     /product="ribosomal 40S subunit protein S29B"
                     /protein_id="NP_010222.1"
                     /db_xref="GI:6320142"
                     /db_xref="SGD:S000002219"
                     /db_xref="GeneID:851498"
                     /translation="MAHENVWFSHPRRFGKGSRQCRVCSSHTGLVRKYDLNICRQCFR
                     EKANDIGFHKYR"
     gene            <341619..>343985
                     /gene="TSR1"
                     /locus_tag="YDL060W"
                     /db_xref="GeneID:851499"
     mRNA            <341619..>343985
                     /gene="TSR1"
                     /locus_tag="YDL060W"
                     /product="Tsr1p"
                     /transcript_id="NM_001180119.1"
                     /db_xref="GI:296143304"
                     /db_xref="GeneID:851499"
     CDS             341619..343985
                     /gene="TSR1"
                     /locus_tag="YDL060W"
                     /note="Protein required for processing of 20S pre-rRNA in
                     the cytoplasm; associates with pre-40S ribosomal
                     particles; inhibits the premature association of 60S
                     subunits with assembling 40S subunits in the cytoplasm;
                     similar to Bms1p; relocalizes from nucleus to cytoplasm
                     upon DNA replication stress"
                     /codon_start=1
                     /product="Tsr1p"
                     /protein_id="NP_010223.1"
                     /db_xref="GI:6320143"
                     /db_xref="SGD:S000002218"
                     /db_xref="GeneID:851499"
                     /translation="MAGHSHRSSLKNGHKSYKSKHASKGALKRLYKGKVEKEPVGTGK
                     PDKQVSKLQRKNKAKQLRAQRILDSIENRKLFEGKNGAAKIITIVPLVNDLDPLDILY
                     KLLKCADDEGIMVQEVDSKRIFNVHIKKFKSNLKIIIPDMTNFLNILDCAKVADFVVF
                     GLSGVQEVDEEFGEQIIRALELQGIASYIGVISNLSAVHEKEKFQLDVKQSLESYFKH
                     FFPSEERVYNLEKNSDALNVLRTLCQRLPRSINWRDNRGYVVADFVDFVETSPDSGDL
                     VIEGTVRGIGFNANRLVHIPDFGDFQLNKIEKISESSQKRKIIKEKATDSLSLELDLQ
                     TVFESNMNRDTLDEYAPEGTEDWSDYDEDFEYDGLTTARYDDHGFLPGREQTSKKAAV
                     PKGTSDYQAKWYLDDVIDANEEEEAEQTNGKDETMMEIDDEMMVEQDNEEVAGDEEYD
                     IEDNEGFEELSPEEEERQLREFRDMEKEDREFPDEIELEPSESAIERLKRYRGLKNLY
                     NCDWQVDEKDPSSPAEWKRLLRIGNYKNTKNRIIKETKNEAQAIAGDRIRMFIRFPKF
                     LLEKIQDPKQLLFAVYGLLLHEHKNAVVNFSLQRWEQYDKPVPSQEPIVVQYGVRRYT
                     IQPLFSQGSNSPNNVHKYERFLHPDTVSVATCIAPVDFTQSPAIFFKPSPTDAKNIEL
                     IGHGTFLNADHSRILAKRAILTGHPFRFHKTVVTVRYMFFRPEDVEWFKSIPLFTKSG
                     RSGFIKESLGTHGYFKATFDGKLSAQDVVAMSLYKRMWPMPSLPWNGM"
     gene            complement(<344237..>344953)
                     /gene="RAD59"
                     /locus_tag="YDL059C"
                     /db_xref="GeneID:851500"
     mRNA            complement(<344237..>344953)
                     /gene="RAD59"
                     /locus_tag="YDL059C"
                     /product="Rad59p"
                     /transcript_id="NM_001180118.1"
                     /db_xref="GI:296143305"
                     /db_xref="GeneID:851500"
     CDS             complement(344237..344953)
                     /gene="RAD59"
                     /locus_tag="YDL059C"
                     /note="Protein involved DNA double-strand break repair;
                     repairs breaks in DNA during vegetative growth via
                     recombination and single-strand annealing; anneals
                     complementary single-stranded DNA; forms nuclear foci upon
                     DNA replication stress; required for loading of Rad52p to
                     DSBs; paralog of Rad52p"
                     /codon_start=1
                     /product="Rad59p"
                     /protein_id="NP_010224.1"
                     /db_xref="GI:6320144"
                     /db_xref="SGD:S000002217"
                     /db_xref="GeneID:851500"
                     /translation="MTIQAKPSSSISYDSTTYGTAPGLDIKEFQIIEDWNGRPASAWS
                     VQRIGLLQSKIERYTYNIYHNNKYGKHNLSKLIPGHALIQFANETFGYDGWRMDVIDV
                     EARECQPFTAVNNGENTNTSEVKYTVVAEAQVKVTLKDGTNTQCGGLGRITLSSRGEC
                     YNRSKKEAVGDALKKALLSFEKIILDYETKITNNYYVDGLYGSKKIKNEANTNYNLLS
                     ATNSKPTFIKLEDAKGTHIK"
     gene            <345665..>351037
                     /gene="USO1"
                     /locus_tag="YDL058W"
                     /gene_synonym="INT1"
                     /db_xref="GeneID:851501"
     mRNA            <345665..>351037
                     /gene="USO1"
                     /locus_tag="YDL058W"
                     /gene_synonym="INT1"
                     /product="Uso1p"
                     /transcript_id="NM_001180117.1"
                     /db_xref="GI:296143306"
                     /db_xref="GeneID:851501"
     CDS             345665..351037
                     /gene="USO1"
                     /locus_tag="YDL058W"
                     /gene_synonym="INT1"
                     /note="Essential protein involved in vesicle-mediated ER
                     to Golgi transport; binds membranes and functions during
                     vesicle docking to the Golgi; required for assembly of the
                     ER-to-Golgi SNARE complex"
                     /codon_start=1
                     /product="Uso1p"
                     /protein_id="NP_010225.1"
                     /db_xref="GI:6320145"
                     /db_xref="SGD:S000002216"
                     /db_xref="GeneID:851501"
                     /translation="MDIIQGLIQQPKIQSVDETIPTLCDRVENSTLISDRRSAVLGLK
                     AFSRQYRESVIASGLKPLLNTLKRDYMDEDSVKAILETILILFIRGDGHDDLTRGWIS
                     QQSRLQNGKYPSPLVMKQEKEQVDQFSLWIADALTQSEDLIHLLVEFWEIDNFHIRLY
                     TIQLLEAVMATRPLKARSALISLPTSISTMVSLLDDMHEPIRDEAILLLMAVVNDSPH
                     VQKLVAFENIFERLFSIIEEEGGLRGSLVVNDCLSLINNILKYNTSNQTLFLETGNLP
                     KLAHLLSEPISQDEVFFWNDQRIVNINTALDIVSLTVEPGNTVTTKHQNALLDSSVLM
                     VVLRLAFFHNIPKKVRPVALLTAANMVRSNEHAQLEFSKIDVPYFDPSLPVNSTANGG
                     PIKLIPVVSILINWMLYANSVHTFDTRVACSRLLKAYFMDNFDLQRDFLLKQVQLCNN
                     STNNVGDNAKENGGSNKSDKESDSDKDTDGKDGTEYEGSFKANLFEVLLNYDAELNLN
                     PFKLFFTTDIFMFFFQQDHKYSEELREITRNVTTGNDLEDEEPLKAIQTISELLTTSL
                     TAADIRIPISYLTFLIYWLFGDFKATNDFLSDKSVIKSLLSFSYQIQDEDVTIKCLVT
                     MLLGVAYEFSSKESPFPRKEYFEFITKTLGKDNYASRIKQFKKDSYFSKVDMNEDSIL
                     TPELDETGLPKVYFSTYFIQLFNENIYRIRTALSHDPDEEPINKISFEEVEKLQRQCT
                     KLKGEITSLQTETESTHENLTEKLIALTNEHKELDEKYQILNSSHSSLKENFSILETE
                     LKNVRDSLDEMTQLRDVLETKDKENQTALLEYKSTIHKQEDSIKTLEKGLETILSQKK
                     KAEDGINKMGKDLFALSREMQAVEENCKNLQKEKDKSNVNHQKETKSLKEDIAAKITE
                     IKAINENLEEMKIQCNNLSKEKEHISKELVEYKSRFQSHDNLVAKLTEKLKSLANNYK
                     DMQAENESLIKAVEESKNESSIQLSNLQNKIDSMSQEKENFQIERGSIEKNIEQLKKT
                     ISDLEQTKEEIISKSDSSKDEYESQISLLKEKLETATTANDENVNKISELTKTREELE
                     AELAAYKNLKNELETKLETSEKALKEVKENEEHLKEEKIQLEKEATETKQQLNSLRAN
                     LESLEKEHEDLAAQLKKYEEQIANKERQYNEEISQLNDEITSTQQENESIKKKNDELE
                     GEVKAMKSTSEEQSNLKKSEIDALNLQIKELKKKNETNEASLLESIKSVESETVKIKE
                     LQDECNFKEKEVSELEDKLKASEDKNSKYLELQKESEKIKEELDAKTTELKIQLEKIT
                     NLSKAKEKSESELSRLKKTSSEERKNAEEQLEKLKNEIQIKNQAFEKERKLLNEGSST
                     ITQEYSEKINTLEDELIRLQNENELKAKEIDNTRSELEKVSLSNDELLEEKQNTIKSL
                     QDEILSYKDKITRNDEKLLSIERDNKRDLESLKEQLRAAQESKAKVEEGLKKLEEESS
                     KEKAELEKSKEMMKKLESTIESNETELKSSMETIRKSDEKLEQSKKSAEEDIKNLQHE
                     KSDLISRINESEKDIEELKSKLRIEAKSGSELETVKQELNNAQEKIRINAEENTVLKS
                     KLEDIERELKDKQAEIKSNQEEKELLTSRLKELEQELDSTQQKAQKSEEERRAEVRKF
                     QVEKSQLDEKAMLLETKYNDLVNKEQAWKRDEDTVKKTTDSQRQEIEKLAKELDNLKA
                     ENSKLKEANEDRSEIDDLMLLVTDLDEKNAKYRSKLKDLGVEISSDEEDDEEDDEEDE
                     EEGQVA"
     gene            <351434..>352420
                     /locus_tag="YDL057W"
                     /db_xref="GeneID:851502"
     mRNA            <351434..>352420
                     /locus_tag="YDL057W"
                     /product="hypothetical protein"
                     /transcript_id="NM_001180116.1"
                     /db_xref="GI:296143307"
                     /db_xref="GeneID:851502"
     CDS             351434..352420
                     /locus_tag="YDL057W"
                     /note="hypothetical protein; YDL057W is not an essential
                     gene"
                     /codon_start=1
                     /product="hypothetical protein"
                     /protein_id="NP_010226.1"
                     /db_xref="GI:6320146"
                     /db_xref="SGD:S000002215"
                     /db_xref="GeneID:851502"
                     /translation="MEKKHVTVQIQSAPPSYIKLEANEKFVYITSTMNGLSYQIAAIV
                     SYPEKRNSSTANKEDGKLLCKENKLALLLHGSQSHKNAIYQTLLAKRLAEFGYWVLRI
                     DFRGQGDSSDNCDPGLGRTLAQDLEDLSTVYQTVSDRSLRVQLYKTSTISLDVVVAHS
                     RGSLAMFKFCLKLHAAESPLPSHLINCAGRYDGRGLIERCTRLHPHWQAEGGFWANGP
                     RNGEYKDFWIPLSETYSIAGVCVPEFATIPQTCSVMSCYGMCDHIVPISAASNYARLF
                     EGRHSLKLIENADHNYYGIEGDPNALGLPIRRGRVNYSPLVVDLIMEYLQDT"
     gene            <352877..>355378
                     /gene="MBP1"
                     /locus_tag="YDL056W"
                     /db_xref="GeneID:851503"
     mRNA            <352877..>355378
                     /gene="MBP1"
                     /locus_tag="YDL056W"
                     /product="Mbp1p"
                     /transcript_id="NM_001180115.1"
                     /db_xref="GI:296143308"
                     /db_xref="GeneID:851503"
     CDS             352877..355378
                     /gene="MBP1"
                     /locus_tag="YDL056W"
                     /note="Transcription factor; involved in regulation of
                     cell cycle progression from G1 to S phase, forms a complex
                     with Swi6p that binds to MluI cell cycle box regulatory
                     element in promoters of DNA synthesis genes"
                     /codon_start=1
                     /product="Mbp1p"
                     /protein_id="NP_010227.1"
                     /db_xref="GI:6320147"
                     /db_xref="SGD:S000002214"
                     /db_xref="GeneID:851503"
                     /translation="MSNQIYSARYSGVDVYEFIHSTGSIMKRKKDDWVNATHILKAAN
                     FAKAKRTRILEKEVLKETHEKVQGGFGKYQGTWVPLNIAKQLAEKFSVYDQLKPLFDF
                     TQTDGSASPPPAPKHHHASKVDRKKAIRSASTSAIMETKRNNKKAEENQFQSSKILGN
                     PTAAPRKRGRPVGSTRGSRRKLGVNLQRSQSDMGFPRPAIPNSSISTTQLPSIRSTMG
                     PQSPTLGILEEERHDSRQQQPQQNNSAQFKEIDLEDGLSSDVEPSQQLQQVFNQNTGF
                     VPQQQSSLIQTQQTESMATSVSSSPSLPTSPGDFADSNPFEERFPGGGTSPIISMIPR
                     YPVTSRPQTSDINDKVNKYLSKLVDYFISNEMKSNKSLPQVLLHPPPHSAPYIDAPID
                     PELHTAFHWACSMGNLPIAEALYEAGTSIRSTNSQGQTPLMRSSLFHNSYTRRTFPRI
                     FQLLHETVFDIDSQSQTVIHHIVKRKSTTPSAVYYLDVVLSKIKDFSPQYRIELLLNT
                     QDKNGDTALHIASKNGDVVFFNTLVKMGALTTISNKEGLTANEIMNQQYEQMMIQNGT
                     NQHVNSSNTDLNIHVNTNNIETKNDVNSMVIMSPVSPSDYITYPSQIATNISRNIPNV
                     VNSMKQMASIYNDLHEQHDNEIKSLQKTLKSISKTKIQVSLKTLEVLKESSKDENGEA
                     QTNDDFEILSRLQEQNTKKLRKRLIRYKRLIKQKLEYRQTVLLNKLIEDETQATTNNT
                     VEKDNNTLERLELAQELTMLQLQRKNKLSSLVKKFEDNAKIHKYRRIIREGTEMNIEE
                     VDSSLDVILQTLIANNNKNKGAEQIITISNANSHA"
     gene            complement(<355674..>356759)
                     /gene="PSA1"
                     /locus_tag="YDL055C"
                     /gene_synonym="MPG1; SRB1; VIG9"
                     /db_xref="GeneID:851504"
     mRNA            complement(<355674..>356759)
                     /gene="PSA1"
                     /locus_tag="YDL055C"
                     /gene_synonym="MPG1; SRB1; VIG9"
                     /product="mannose-1-phosphate guanylyltransferase"
                     /transcript_id="NM_001180114.1"
                     /db_xref="GI:296143309"
                     /db_xref="GeneID:851504"
     CDS             complement(355674..356759)
                     /gene="PSA1"
                     /locus_tag="YDL055C"
                     /gene_synonym="MPG1; SRB1; VIG9"
                     /EC_number="2.7.7.13"
                     /note="GDP-mannose pyrophosphorylase (mannose-1-phosphate
                     guanyltransferase); synthesizes GDP-mannose from GTP and
                     mannose-1-phosphate in cell wall biosynthesis; required
                     for normal cell wall structure"
                     /codon_start=1
                     /product="mannose-1-phosphate guanylyltransferase"
                     /protein_id="NP_010228.1"
                     /db_xref="GI:6320148"
                     /db_xref="SGD:S000002213"
                     /db_xref="GeneID:851504"
                     /translation="MKGLILVGGYGTRLRPLTLTVPKPLVEFGNRPMILHQIEALANA
                     GVTDIVLAVNYRPEVMVETLKKYEKEYGVNITFSVETEPLGTAGPLKLAEDVLKKDNS
                     PFFVLNSDVICEYPFKELADFHKAHGGKGTIVATKVDEPSKYGVIVHDIATPNLIDRF
                     VEKPKEFVGNRINAGLYILNPEVIDLIEMKPTSIEKETFPILVEEKQLYSFDLEGFWM
                     DVGQPKDFLSGTVLYLNSLAKRQPKKLATGANIVGNALIDPTAKISSTAKIGPDVVIG
                     PNVTIGDGVRITRSVVLCNSTIKNHSLVKSTIVGWNSTVGQWCRLEGVTVLGDDVEVK
                     DEIYINGGKVLPHKSISDNVPKEAIIM"
     gene            359577..359672
                     /locus_tag="tK(UUU)D"
                     /db_xref="GeneID:851505"
     tRNA            join(359577..359613,359637..359672)
                     /locus_tag="tK(UUU)D"
                     /product="tRNA-Lys"
                     /note="Lysine tRNA (tRNA-Lys), predicted by tRNAscan-SE
                     analysis; thiolation of uridine at wobble position (34)
                     requires Ncs6p"
                     /db_xref="SGD:S000006629"
                     /db_xref="GeneID:851505"
     gene            complement(<359825..>361285)
                     /gene="MCH1"
                     /locus_tag="YDL054C"
                     /db_xref="GeneID:851506"
     mRNA            complement(<359825..>361285)
                     /gene="MCH1"
                     /locus_tag="YDL054C"
                     /product="Mch1p"
                     /transcript_id="NM_001180113.1"
                     /db_xref="GI:296143310"
                     /db_xref="GeneID:851506"
     CDS             complement(359825..361285)
                     /gene="MCH1"
                     /locus_tag="YDL054C"
                     /note="Protein with similarity to mammalian
                     monocarboxylate permeases; monocarboxylate permeases are
                     involved in transport of monocarboxylic acids across the
                     plasma membrane but mutant is not deficient in
                     monocarboxylate transport"
                     /codon_start=1
                     /product="Mch1p"
                     /protein_id="NP_010229.1"
                     /db_xref="GI:6320149"
                     /db_xref="SGD:S000002212"
                     /db_xref="GeneID:851506"
                     /translation="MPLSKVEHYLSYHTRLLLPHVLSLQSSHRVAYIFSLLSAVSTGF
                     ITLISLYSQPWQKHLNYSSWQINTIASMTNLGMYLTPPILGMIADSHGPITLSLLAII
                     GFIPSYSYLAYVFNHPELSLGGNGDSSFNLSIICFVFIGISTSALYFSALLTCTKLYP
                     HTKLLSISLPTTCYGISSVVGSQLLRIKWFWSSNASSSSSNSDLNLGRVFQTFALVYV
                     VIGLLAWIATSVVSLLHFNEEQDNQKRLDDQTDVEQSPLLERSNHVQEKFTQTMLRIF
                     SDPVTYILAVSILLSLGPLEMFIANMGSLTNLLVQLDAPTLSTKLLSTYALSSTFTRL
                     LTGIVADFFAKKKISIKWILLTFLSLGVCAQLFLLKMTSSASPWGLVPTGSLVGIVYG
                     GLFTVYPTLVLLVWGERSFGTVYGSLLIAPAIGSMIFCMLYAKFYDSRCMSGGGDLRN
                     PSCISAVYKYSSIAFVVSAVLSAVVFWKLKSRKLRI"
     gene            complement(<361699..>362256)
                     /gene="PBP4"
                     /locus_tag="YDL053C"
                     /db_xref="GeneID:851507"
     mRNA            complement(<361699..>362256)
                     /gene="PBP4"
                     /locus_tag="YDL053C"
                     /product="Pbp4p"
                     /transcript_id="NM_001180112.1"
                     /db_xref="GI:296143311"
                     /db_xref="GeneID:851507"
     CDS             complement(361699..362256)
                     /gene="PBP4"
                     /locus_tag="YDL053C"
                     /note="Pbp1p binding protein; interacts strongly with
                     Pab1p-binding protein 1 (Pbp1p) in the yeast two-hybrid
                     system; also interacts with Lsm12p in a copurification
                     assay; relative distribution to the nucleus increases upon
                     DNA replication stress"
                     /codon_start=1
                     /product="Pbp4p"
                     /protein_id="NP_010230.1"
                     /db_xref="GI:6320150"
                     /db_xref="SGD:S000002211"
                     /db_xref="GeneID:851507"
                     /translation="MTTTSTTSVDGRTSSTLKATLSASGPNSNGPTPAVLPQKPKLTG
                     WAQAAAKALPRQQQQQQQARKDDSVAVQPANTKTKTIASTAPPANIKGSSTANGSSTN
                     KKFKRANKQPYNREEVRSYMHKLFQSYTAGEKSHSMKTYKQVLSETASGRVSTATDWG
                     TVSSSKNKNKKYGCLSDIAKVLRNQ"
     gene            complement(<362672..>363583)
                     /gene="SLC1"
                     /locus_tag="YDL052C"
                     /db_xref="GeneID:851508"
     mRNA            complement(<362672..>363583)
                     /gene="SLC1"
                     /locus_tag="YDL052C"
                     /product="1-acylglycerol-3-phosphate O-acyltransferase
                     SLC1"
                     /transcript_id="NM_001180111.1"
                     /db_xref="GI:296143312"
                     /db_xref="GeneID:851508"
     CDS             complement(362672..363583)
                     /gene="SLC1"
                     /locus_tag="YDL052C"
                     /EC_number="2.3.1.51"
                     /note="1-acyl-sn-glycerol-3-phosphate acyltransferase;
                     catalyzes the acylation of lysophosphatidic acid to form
                     phosphatidic acid, a key intermediate in lipid metabolism;
                     enzymatic activity detected in lipid particles and
                     microsomes"
                     /codon_start=1
                     /product="1-acylglycerol-3-phosphate O-acyltransferase
                     SLC1"
                     /protein_id="NP_010231.1"
                     /db_xref="GI:6320151"
                     /db_xref="SGD:S000002210"
                     /db_xref="GeneID:851508"
                     /translation="MSVIGRFLYYLRSVLVVLALAGCGFYGVIASILCTLIGKQHLAQ
                     WITARCFYHVMKLMLGLDVKVVGEENLAKKPYIMIANHQSTLDIFMLGRIFPPGCTVT
                     AKKSLKYVPFLGWFMALSGTYFLDRSKRQEAIDTLNKGLENVKKNKRALWVFPEGTRS
                     YTSELTMLPFKKGAFHLAQQGKIPIVPVVVSNTSTLVSPKYGVFNRGCMIVRILKPIS
                     TENLTKDKIGEFAEKVRDQMVDTLKEIGYSPAINDTTLPPQAIEYAALQHDKKVNKKI
                     KNEPVPSVSISNDVNTHNEGSSVKKMH"
     gene            <363952..>364779
                     /gene="LHP1"
                     /locus_tag="YDL051W"
                     /gene_synonym="LAH1; YLA1"
                     /db_xref="GeneID:851509"
     mRNA            <363952..>364779
                     /gene="LHP1"
                     /locus_tag="YDL051W"
                     /gene_synonym="LAH1; YLA1"
                     /product="Lhp1p"
                     /transcript_id="NM_001180110.1"
                     /db_xref="GI:296143313"
                     /db_xref="GeneID:851509"
     CDS             363952..364779
                     /gene="LHP1"
                     /locus_tag="YDL051W"
                     /gene_synonym="LAH1; YLA1"
                     /note="RNA binding protein required for maturation of tRNA
                     and U6 snRNA; acts as a molecular chaperone for RNAs
                     transcribed by polymerase III; homologous to human La
                     (SS-B) autoantigen"
                     /codon_start=1
                     /product="Lhp1p"
                     /protein_id="NP_010232.1"
                     /db_xref="GI:6320152"
                     /db_xref="SGD:S000002209"
                     /db_xref="GeneID:851509"
                     /translation="MSEKPQQEEQEKPQSRRNSFAVIEFTPEVLDRCLKQVEFYFSEF
                     NFPYDRFLRTTAEKNDGWVPISTIATFNRMKKYRPVDKVIEALRSSEILEVSADGENV
                     KRRVPLDLTAARNARIEQNQRTLAVMNFPHEDVEASQIPELQENLEAFFKKLGEINQV
                     RLRRDHRNKKFNGTVLVEFKTIPECEAFLKSYSNDDESNEILSYEGKKLSVLTKKQFD
                     LQREASKSKNFSGRSRSFNGHKKKNLPKFPKNKKKNGKEESKEDSSAIADDDEEHKE"
     gene            complement(<365068..>365874)
                     /gene="KNH1"
                     /locus_tag="YDL049C"
                     /db_xref="GeneID:851511"
     mRNA            complement(<365068..>365874)
                     /gene="KNH1"
                     /locus_tag="YDL049C"
                     /product="Knh1p"
                     /transcript_id="NM_001180108.1"
                     /db_xref="GI:296143314"
                     /db_xref="GeneID:851511"
     CDS             complement(365068..365874)
                     /gene="KNH1"
                     /locus_tag="YDL049C"
                     /note="Protein with similarity to Kre9p; Kre9p is involved
                     in cell wall beta 1,6-glucan synthesis; overproduction
                     suppresses growth defects of a kre9 null mutant; required
                     for propionic acid resistance"
                     /codon_start=1
                     /product="Knh1p"
                     /protein_id="NP_010234.1"
                     /db_xref="GI:6320154"
                     /db_xref="SGD:S000002207"
                     /db_xref="GeneID:851511"
                     /translation="MLIVLFLTLFCSVVFRTAYCDVAIVAPEPNSVYDLSGTSQAVVK
                     VKWMHTDNTPQEKDFVRYTFTLCSGTNAMIEAMATLQTLSASDLTDNEFNAIIENTVG
                     TDGVYFIQVFAQTAIGYTIHYTNRFKLKGMIGTKAANPSMITIAPEAQTRITTGDVGA
                     TIDSKSFTVPYNLQTGVVKYAPMQLQPATKVTAKTWKRKYATSEVTYYYTLRNSVDQH
                     TTVTPGWSYIITADSNYATPAPMPADNGGWYNPRKRLSLTARKVNALRHR"
     gene            complement(<366739..>368211)
                     /gene="STP4"
                     /locus_tag="YDL048C"
                     /db_xref="GeneID:851512"
     mRNA            complement(<366739..>368211)
                     /gene="STP4"
                     /locus_tag="YDL048C"
                     /product="Stp4p"
                     /transcript_id="NM_001180107.1"
                     /db_xref="GI:296143315"
                     /db_xref="GeneID:851512"
     CDS             complement(366739..368211)
                     /gene="STP4"
                     /locus_tag="YDL048C"
                     /note="Protein containing a Kruppel-type zinc-finger
                     domain; similar to Stp1p, Stp2p; predicted transcription
                     factor; relative distribution to the nucleus increases
                     upon DNA replication stress; STP4 has a paralog, STP3,
                     that arose from the whole genome duplication"
                     /codon_start=1
                     /product="Stp4p"
                     /protein_id="NP_010235.1"
                     /db_xref="GI:6320155"
                     /db_xref="SGD:S000002206"
                     /db_xref="GeneID:851512"
                     /translation="MLVSSSFASSIDSVMSHETMSLRRNPPFIDTPEKMPNPTASPNG
                     TIHHLIDPSLPLLSSTTSSSRSTLSSTLNSPPPPPLTTSYSSYNSSACQSITSSPTDN
                     TALAHNSKCYFPHSLSPTPLSSNSSSHVILPPISSFTNLITVAEREFNGRSNSLHANF
                     TSPVPRTVLDHHRHELTFCNPNNTTGFKTITPSPPTQHQSILPTAVDNVPRSKSVSSL
                     PVSGFPPLIVKQQQQQQLNSSSSASALPSIHSPLTNEHTSRYSSSLKDSAKITKQRKK
                     KECPICHNFYANLSTHKSTHLTPEDRPHKCPICQRGFARNNDLIRHKKRHWKDEFMQI
                     YARESDNNSGADDQDDTARTSANNDSDDSNDKLAASSSSEETKLLKKNQLKSLYKIKG
                     AFKCPYNSTLINLDMEVYPHKSRSLYFEPINCHQTGVFSRCDTFKNHLKALHFEYPPK
                     TKKEDRGVVPGKCKHCGLQFPNVDVWLNKHVGKGCGYSYH"
     gene            <369771..>370706
                     /gene="SIT4"
                     /locus_tag="YDL047W"
                     /gene_synonym="PPH1"
                     /db_xref="GeneID:851513"
     mRNA            <369771..>370706
                     /gene="SIT4"
                     /locus_tag="YDL047W"
                     /gene_synonym="PPH1"
                     /product="type 2A-related serine/threonine-protein
                     phosphatase SIT4"
                     /transcript_id="NM_001180106.1"
                     /db_xref="GI:296143316"
                     /db_xref="GeneID:851513"
     CDS             369771..370706
                     /gene="SIT4"
                     /locus_tag="YDL047W"
                     /gene_synonym="PPH1"
                     /EC_number="3.1.3.16"
                     /note="Type 2A-related serine-threonine phosphatase;
                     functions in the G1/S transition of the mitotic cycle;
                     regulator of COPII coat dephosphorylation; required for ER
                     to Golgi traffic; interacts with Hrr25p kinase;
                     cytoplasmic and nuclear protein that modulates functions
                     mediated by Pkc1p including cell wall and actin
                     cytoskeleton organization; similar to human PP6"
                     /codon_start=1
                     /product="type 2A-related serine/threonine-protein
                     phosphatase SIT4"
                     /protein_id="NP_010236.1"
                     /db_xref="GI:6320156"
                     /db_xref="SGD:S000002205"
                     /db_xref="GeneID:851513"
                     /translation="MVSRGPDEWLETIKKCQALTENEMKQLCEMVKELLMEESNIQPV
                     QTPVTVCGDIHGQFHDLLELFRTAGGFPDDINYIFLGDYVDRGYYSLETFTLLMCLKV
                     KYPAKITLVRGNHESRQITQVYGFYEECLNKYGSTTVWKYCCQVFDFLTLAAIIDGKI
                     LCVHGGLSPEIRMLDQIRVLSRAQEVPHEGGFSDLLWSDPDNVEAWQVSPRGAGWLFG
                     SKVAREFNHVNGLNLIARAHQLVMEGFKYHFPEKDVVTVWSAPNYCYRCGNVASVMKV
                     DEDLEPTFKIFSAVPDDYIRESTANHNNQRAGYFL"
     gene            <371240..>371761
                     /gene="NPC2"
                     /locus_tag="YDL046W"
                     /db_xref="GeneID:851514"
     mRNA            <371240..>371761
                     /gene="NPC2"
                     /locus_tag="YDL046W"
                     /product="Npc2p"
                     /transcript_id="NM_001180105.1"
                     /db_xref="GI:296143317"
                     /db_xref="GeneID:851514"
     CDS             371240..371761
                     /gene="NPC2"
                     /locus_tag="YDL046W"
                     /note="Functional homolog of human NPC2/He1; human NPC2 is
                     a cholesterol-binding protein whose deficiency causes
                     Niemann-Pick type C2 disease involving retention of
                     cholesterol in lysosomes"
                     /codon_start=1
                     /product="Npc2p"
                     /protein_id="NP_010237.1"
                     /db_xref="GI:6320157"
                     /db_xref="SGD:S000002204"
                     /db_xref="GeneID:851514"
                     /translation="MTHSLKALFALLFLYTAAVNAGVIGIFNALPPPNTKPINGESPL
                     YQCDILDKQLVEIKEVNLDPNPPVRGENLTISANGEVFETIEEGAYIDVEVRLGYIRL
                     LSQTFDLCETLEDNDIEGLSCPIEPGEYNIKKIVEIPGEVPPGKYVVVARAYTEKDDL
                     ITCLTGEVIFPPR"
     gene            <372248..>372535
                     /gene="MRP10"
                     /locus_tag="YDL045W-A"
                     /db_xref="GeneID:851515"
     mRNA            <372248..>372535
                     /gene="MRP10"
                     /locus_tag="YDL045W-A"
                     /product="mitochondrial 37S ribosomal protein YmS-T"
                     /transcript_id="NM_001184304.1"
                     /db_xref="GI:296143318"
                     /db_xref="GeneID:851515"
     CDS             372248..372535
                     /gene="MRP10"
                     /locus_tag="YDL045W-A"
                     /note="Mitochondrial ribosomal protein of the small
                     subunit; contains twin cysteine-x9-cysteine motifs;
                     oxidized by Mia40p during import into mitochondria"
                     /codon_start=1
                     /product="mitochondrial 37S ribosomal protein YmS-T"
                     /protein_id="NP_010238.1"
                     /db_xref="GI:6320158"
                     /db_xref="SGD:S000006430"
                     /db_xref="GeneID:851515"
                     /translation="MSGKPPVYRLPPLPRLKVKKPIIRQEANKCLVLMSNLLQCWSSY
                     GHMSPKCAGLVTELKSCTSESALGKRNNVQKSNINYHAARLYDRINGKPHD"
     gene            complement(<372688..>373608)
                     /gene="FAD1"
                     /locus_tag="YDL045C"
                     /db_xref="GeneID:851516"
     mRNA            complement(<372688..>373608)
                     /gene="FAD1"
                     /locus_tag="YDL045C"
                     /product="FMN adenylyltransferase"
                     /transcript_id="NM_001180104.1"
                     /db_xref="GI:296143319"
                     /db_xref="GeneID:851516"
     CDS             complement(372688..373608)
                     /gene="FAD1"
                     /locus_tag="YDL045C"
                     /EC_number="2.7.7.2"
                     /note="Flavin adenine dinucleotide (FAD) synthetase;
                     performs the second step in synthesis of FAD from
                     riboflavin"
                     /codon_start=1
                     /product="FMN adenylyltransferase"
                     /protein_id="NP_010239.1"
                     /db_xref="GI:6320159"
                     /db_xref="SGD:S000002203"
                     /db_xref="GeneID:851516"
                     /translation="MQLSKAAEMCYEITNSYLHIDQKSQIIASTQEAIRLTRKYLLSE
                     IFVRWSPLNGEISFSYNGGKDCQVLLLLYLSCLWEYFFIKAQNSQFDFEFQSFPMQRL
                     PTVFIDQEETFPTLENFVLETSERYCLSLYESQRQSGASVNMADAFRDFIKIYPETEA
                     IVIGIRHTDPFGEALKPIQRTDSNWPDFMRLQPLLHWDLTNIWSFLLYSNEPICGLYG
                     KGFTSIGGINNSLPNPHLRKDSNNPALHFEWEIIHAFGKDAEGERSSAINTSPISVVD
                     KERFSKYHDNYYPGWYLVDDTLERAGRIKN"
     gene            complement(<373967..>375289)
                     /gene="MTF2"
                     /locus_tag="YDL044C"
                     /gene_synonym="NAM1"
                     /db_xref="GeneID:851517"
     mRNA            complement(<373967..>375289)
                     /gene="MTF2"
                     /locus_tag="YDL044C"
                     /gene_synonym="NAM1"
                     /product="Mtf2p"
                     /transcript_id="NM_001180103.1"
                     /db_xref="GI:296143320"
                     /db_xref="GeneID:851517"
     CDS             complement(373967..375289)
                     /gene="MTF2"
                     /locus_tag="YDL044C"
                     /gene_synonym="NAM1"
                     /note="Mitochondrial protein that interacts with
                     mitochondrial RNA polymerase; interacts with an N-terminal
                     region of mitochondrial RNA polymerase (Rpo41p) and
                     couples RNA processing and translation to transcription"
                     /codon_start=1
                     /product="Mtf2p"
                     /protein_id="NP_010240.1"
                     /db_xref="GI:6320160"
                     /db_xref="SGD:S000002202"
                     /db_xref="GeneID:851517"
                     /translation="MIRTSSILKNCNYRYIHCIHRCLLNEANLKDRKTHNVERVSNEK
                     TFEQALEEERKVFGELFEAGARVENMRHTNASKIIDKYYNGLQDNSEGTSVKKEKIVF
                     NHSQRAQRKLPNKDHEFLKETAGNDYVYERAEPSAISTKTISEQTRTLLEKIFDEDNS
                     INKSNRELLNLNLRKGSGMEALRQPVAHSNVKFSEEVMQEIGNKIRYQTTLDQVLEPH
                     IDYLREAVKSDYDLLRYLKQSLDIYKKRNKDLELKMNAESSNIFEDIRSACINKPAEL
                     PKPLAMTLPYIIVKSLRLGDFDFPADRKYTLISYVYNECKNNMDASLYLTICNVDFYN
                     LLVQLLWENFQEIRYLRRVVTEMSVNGVIGNIETVDILDKIVKEMRSLNEDVFLEAGE
                     QLSADEEVSSSANKIVNVGVLWNKDTNNDLLIVENYLKSLKKNLTRDR"
     gene            complement(<375680..>376480)
                     /gene="PRP11"
                     /locus_tag="YDL043C"
                     /gene_synonym="RNA11"
                     /db_xref="GeneID:851518"
     mRNA            complement(<375680..>376480)
                     /gene="PRP11"
                     /locus_tag="YDL043C"
                     /gene_synonym="RNA11"
                     /product="Prp11p"
                     /transcript_id="NM_001180102.1"
                     /db_xref="GI:296143321"
                     /db_xref="GeneID:851518"
     CDS             complement(375680..376480)
                     /gene="PRP11"
                     /locus_tag="YDL043C"
                     /gene_synonym="RNA11"
                     /note="Subunit of the SF3a splicing factor complex;
                     required for spliceosome assembly"
                     /codon_start=1
                     /product="Prp11p"
                     /protein_id="NP_010241.1"
                     /db_xref="GI:6320161"
                     /db_xref="SGD:S000002201"
                     /db_xref="GeneID:851518"
                     /translation="MNYLEGVGSKKGGGGIASESQFNLQRRKEVESLLSKGENVPYTF
                     QDEKDDQVRSNPYIYKNHSGKLVCKLCNTMHMSWSSVERHLGGKKHGLNVLRRGISIE
                     KSSLGREGQTTHDFRQQQKIIEAKQSLKNNGTIPVCKIATVKNPKNGSVGLAIQVNYS
                     SEVKENSVDSDDKAKVPPLIRIVSGLELSDTKQKGKKFLVIAYEPFENIAIELPPNEI
                     LFSENNDMDNNNDGVDELNKKCTFWDAISKLYYVQFFFKQAEQEQADV"
     gene            complement(<376757..>378445)
                     /gene="SIR2"
                     /locus_tag="YDL042C"
                     /gene_synonym="MAR1"
                     /db_xref="GeneID:851520"
     mRNA            complement(<376757..>378445)
                     /gene="SIR2"
                     /locus_tag="YDL042C"
                     /gene_synonym="MAR1"
                     /product="Sir2p"
                     /transcript_id="NM_001180101.1"
                     /db_xref="GI:296143322"
                     /db_xref="GeneID:851520"
     CDS             complement(376757..378445)
                     /gene="SIR2"
                     /locus_tag="YDL042C"
                     /gene_synonym="MAR1"
                     /EC_number="3.5.1.-"
                     /note="Conserved NAD+ dependent histone deacetylase of the
                     Sirtuin family; involved in regulation of lifespan; plays
                     roles in silencing at HML, HMR, telomeres, and the rDNA
                     locus; negatively regulates initiation of DNA replication;
                     functions as a regulator of autophagy like mammalian
                     homolog SIRT1, and also of mitophagy; SIR2 has a paralog,
                     HST1, that arose from the whole genome duplication"
                     /codon_start=1
                     /product="Sir2p"
                     /protein_id="NP_010242.1"
                     /db_xref="GI:6320163"
                     /db_xref="SGD:S000002200"
                     /db_xref="GeneID:851520"
                     /translation="MTIPHMKYAVSKTSENKVSNTVSPTQDKDAIRKQPDDIINNDEP
                     SHKKIKVAQPDSLRETNTTDPLGHTKAALGEVASMELKPTNDMDPLAVSAASVVSMSN
                     DVLKPETPKGPIIISKNPSNGIFYGPSFTKRESLNARMFLKYYGAHKFLDTYLPEDLN
                     SLYIYYLIKLLGFEVKDQALIGTINSIVHINSQERVQDLGSAISVTNVEDPLAKKQTV
                     RLIKDLQRAINKVLCTRLRLSNFFTIDHFIQKLHTARKILVLTGAGVSTSLGIPDFRS
                     SEGFYSKIKHLGLDDPQDVFNYNIFMHDPSVFYNIANMVLPPEKIYSPLHSFIKMLQM
                     KGKLLRNYTQNIDNLESYAGISTDKLVQCHGSFATATCVTCHWNLPGERIFNKIRNLE
                     LPLCPYCYKKRREYFPEGYNNKVGVAASQGSMSERPPYILNSYGVLKPDITFFGEALP
                     NKFHKSIREDILECDLLICIGTSLKVAPVSEIVNMVPSHVPQVLINRDPVKHAEFDLS
                     LLGYCDDIAAMVAQKCGWTIPHKKWNDLKNKNFKCQEKDKGVYVVTSDEHPKTL"
     gene            complement(<378874..>381438)
                     /gene="NAT1"
                     /locus_tag="YDL040C"
                     /gene_synonym="AAA1; NAA15"
                     /db_xref="GeneID:851521"
     mRNA            complement(<378874..>381438)
                     /gene="NAT1"
                     /locus_tag="YDL040C"
                     /gene_synonym="AAA1; NAA15"
                     /product="Nat1p"
                     /transcript_id="NM_001180099.1"
                     /db_xref="GI:296143323"
                     /db_xref="GeneID:851521"
     CDS             complement(378874..381438)
                     /gene="NAT1"
                     /locus_tag="YDL040C"
                     /gene_synonym="AAA1; NAA15"
                     /note="Subunit of protein N-terminal acetyltransferase
                     NatA; NatA is comprised of Nat1p, Ard1p, and Nat5p;
                     N-terminally acetylates many proteins, which influences
                     multiple processes such as the cell cycle, heat-shock
                     resistance, mating, sporulation, and telomeric silencing"
                     /codon_start=1
                     /product="Nat1p"
                     /protein_id="NP_010244.1"
                     /db_xref="GI:6320164"
                     /db_xref="SGD:S000002198"
                     /db_xref="GeneID:851521"
                     /translation="MSRKRSTKPKPAAKIALKKENDQFLEALKLYEGKQYKKSLKLLD
                     AILKKDGSHVDSLALKGLDLYSVGEKDDAASYVANAIRKIEGASASPICCHVLGIYMR
                     NTKEYKESIKWFTAALNNGSTNKQIYRDLATLQSQIGDFKNALVSRKKYWEAFLGYRA
                     NWTSLAVAQDVNGERQQAINTLSQFEKLAEGKISDSEKYEHSECLMYKNDIMYKAASD
                     NQDKLQNVLKHLNDIEPCVFDKFGLLERKATIYMKLGQLKDASIVYRTLIKRNPDNFK
                     YYKLLEVSLGIQGDNKLKKALYGKLEQFYPRCEPPKFIPLTFLQDKEELSKKLREYVL
                     PQLERGVPATFSNVKPLYQRRKSKVSPLLEKIVLDYLSGLDPTQDPIPFIWTNYYLSQ
                     HFLFLKDFPKAQEYIDAALDHTPTLVEFYILKARILKHLGLMDTAAGILEEGRQLDLQ
                     DRFINCKTVKYFLRANNIDKAVEVASLFTKNDDSVNGIKDLHLVEASWFIVEQAEAYY
                     RLYLDRKKKLDDLASLKKEVESDKSEQIANDIKENQWLVRKYKGLALKRFNAIPKFYK
                     QFEDDQLDFHSYCMRKGTPRAYLEMLEWGKALYTKPMYVRAMKEASKLYFQMHDDRLK
                     RKSDSLDENSDEIQNNGQNSSSQKKKAKKEAAAMNKRKETEAKSVAAYPSDQDNDVFG
                     EKLIETSTPMEDFATEFYNNYSMQVREDERDYILDFEFNYRIGKLALCFASLNKFAKR
                     FGTTSGLFGSMAIVLLHATRNDTPFDPILKKVVTKSLEKEYSENFPLNEISNNSFDWL
                     NFYQEKFGKNDINGLLFLYRYRDDVPIGSSNLKEMIISSLSPLEPHSQNEILQYYL"
     gene            complement(<381985..>384081)
                     /gene="PRM7"
                     /locus_tag="YDL039C"
                     /gene_synonym="YDL038C"
                     /db_xref="GeneID:851522"
     mRNA            complement(<381985..>384081)
                     /gene="PRM7"
                     /locus_tag="YDL039C"
                     /gene_synonym="YDL038C"
                     /product="Prm7p"
                     /transcript_id="NM_001180098.1"
                     /db_xref="GI:296143324"
                     /db_xref="GeneID:851522"
     CDS             complement(381985..384081)
                     /gene="PRM7"
                     /locus_tag="YDL039C"
                     /gene_synonym="YDL038C"
                     /note="Pheromone-regulated protein; predicted to have one
                     transmembrane segment; promoter contains Gcn4p binding
                     elements"
                     /codon_start=1
                     /product="Prm7p"
                     /protein_id="NP_010245.2"
                     /db_xref="GI:269970297"
                     /db_xref="SGD:S000002197"
                     /db_xref="GeneID:851522"
                     /translation="MYRTRSSDEVTTSTDLTSSSDVATSVDPTTSVISSTSADPTTSA
                     DSTTSTVQTTSAGPSNNIGNSTLANSTTFAVSSTSIDPTSSSDVITSTVQTTSIEPTT
                     SLVSSNDITTSTSLNISVVISTSTDSTSLIESTTTVGPHASSSVAGMYRTRSSDEVTT
                     STDPTSSSDVATSADPTSSSAVTTLVDPTTSVVISTSVDQTSSSDVATSVDPTTSVIS
                     STSADPTTSADSTTSTVQTTSVDPTSSVVSSAPVDPASSVVSLTSSYPTSSSTVTISA
                     NSNGSATLAAQTTSIDPVSSIVSSSGATTIISSASIDPASSVVSSTSSEPTSFIVSST
                     SVYSTRPSGPTTSTDLATFSDTIILRVSTTSTSQDTQTVSSSLTDMVSSTGSADLSVS
                     SIQRSQVDPSTFAVSNSPVYPTASTGSTSTGIPIASESLSLSRQQGISATSSSSIVTL
                     TPVDSASSSRSSATSIIKPNMPVSSNDSKTQSSVSVVDAFQSTKSSYPSITSADPTTL
                     ASENGLVGSSSSAHPITLDRTYASAHASVTDIVSRVTDSTRHTTLVTSNINIQSEVGN
                     PNYSGPKDTTITKQSAFMTSPASTSTISNVQSTASVMNHSIEDNISAAASLESVSGTS
                     TKDYSSQSSAIHYTNSFTTTTTNAFITSKHSIAAVSTGAITSSASISLIMEGSANIEA
                     VGKLVWLAAALPLAFI"
     gene            complement(<384601..>385587)
                     /gene="BSC1"
                     /locus_tag="YDL037C"
                     /db_xref="GeneID:851524"
     mRNA            complement(<384601..>385587)
                     /gene="BSC1"
                     /locus_tag="YDL037C"
                     /product="Bsc1p"
                     /transcript_id="NM_001180096.1"
                     /db_xref="GI:296143325"
                     /db_xref="GeneID:851524"
     CDS             complement(384601..385587)
                     /gene="BSC1"
                     /locus_tag="YDL037C"
                     /note="Protein of unconfirmed function; similar to cell
                     surface flocculin Flo11p; ORF exhibits genomic
                     organization compatible with a translational
                     readthrough-dependent mode of expression"
                     /codon_start=1
                     /product="Bsc1p"
                     /protein_id="NP_010247.1"
                     /db_xref="GI:6320167"
                     /db_xref="SGD:S000002195"
                     /db_xref="GeneID:851524"
                     /translation="MSQQNILHYDMDVTSVSWVKDNTYQITIHVKAVKDIPLKYLWSL
                     KIIGVNGPSSTVQLYGKNEKTYLISDPTDFTSTFQVYAYPSSDGCTVWMPNFQIQFEY
                     LQGDAAQYWQTWQWGTTTFDLSTGCNNYDNQGHSQTDFPGFYWTYQCKGNNDGTCTKA
                     SSSSITTSSITTSSTTTSSTTTSSTTTSSSTTSSSTTSSSTTSSSTTSSSTTSSSTTS
                     SSTTSSSTTSSSTTSSSTTSSSTTSSSTKTSTTTSSTVKSSSTTSIDFTTSVDSHTSS
                     SVADIYRSRTSTDVTTLAASTSPFSSFTSSDSSSSSDVTSSTIQTTSVDPTT"
     gene            complement(<387513..>388901)
                     /gene="PUS9"
                     /locus_tag="YDL036C"
                     /db_xref="GeneID:851525"
     mRNA            complement(<387513..>388901)
                     /gene="PUS9"
                     /locus_tag="YDL036C"
                     /product="pseudouridine synthase PUS9"
                     /transcript_id="NM_001180095.1"
                     /db_xref="GI:296143326"
                     /db_xref="GeneID:851525"
     CDS             complement(387513..388901)
                     /gene="PUS9"
                     /locus_tag="YDL036C"
                     /EC_number="5.4.99.28"
                     /note="Mitochondrial tRNA:pseudouridine synthase;
                     catalyzes the formation of pseudouridine at position 32 in
                     mitochondrial tRNAs; contains an N-terminal mitochondrial
                     targeting sequence; PUS9 has a paralog, RIB2, that arose
                     from the whole genome duplication"
                     /codon_start=1
                     /product="pseudouridine synthase PUS9"
                     /protein_id="NP_010248.1"
                     /db_xref="GI:6320168"
                     /db_xref="SGD:S000002194"
                     /db_xref="GeneID:851525"
                     /translation="MQRNNRLRNLFTVPVIMARQLKRNALSAGLAFAGNATSNEFDEH
                     LQNEVEREREIQKKKKIKRTQSKKSPDLINKSTFQSRTIGSKKEKHRQLDPEYEIVID
                     GPLRKIKPYHFTYRTFCKERWRDKKLVDVFISEFRDRESEYYKRTIENGDVHINDETA
                     DLSTVIRNGDLITHQVHRHEPPVTSRPIKVIFEDDNIMVIDKPSGIPVHPTGRYRFNT
                     ITKMLQNNLGFVVNPCNRLDRLTSGLMFLAKTPKGADNIGDQLKAREVTKEYVAKVVG
                     EFPETEVIVEKPLKLIEPRLALNAVCQMDEKGAKHAKTVFNRISYDGKTSIVKCKPLT
                     GRSHQIRVHLQYLGHPIANDPIYSNDEVWGNNLGKGGQADFDIVITKLDEIGKRKPAK
                     SWFHSNGGYGEVLRQEKCSICESDLYTDPGPNDLDLWLHAYLYESTETEEGTEKKKWC
                     YKTEYPEWALRR"
     gene            complement(<389172..>392057)
                     /gene="GPR1"
                     /locus_tag="YDL035C"
                     /db_xref="GeneID:851527"
     mRNA            complement(<389172..>392057)
                     /gene="GPR1"
                     /locus_tag="YDL035C"
                     /product="Gpr1p"
                     /transcript_id="NM_001180094.1"
                     /db_xref="GI:296143327"
                     /db_xref="GeneID:851527"
     CDS             complement(389172..392057)
                     /gene="GPR1"
                     /locus_tag="YDL035C"
                     /note="Plasma membrane G protein coupled receptor (GPCR);
                     interacts with the heterotrimeric G protein alpha subunit,
                     Gpa2p, and with Plc1p; sensor that integrates nutritional
                     signals with the modulation of cell fate via PKA and cAMP
                     synthesis"
                     /codon_start=1
                     /product="Gpr1p"
                     /protein_id="NP_010249.1"
                     /db_xref="GI:6320170"
                     /db_xref="SGD:S000002193"
                     /db_xref="GeneID:851527"
                     /translation="MITEGFPPNLNALKGSSLLEKRVDSLRQLNTTTVNQLLGLPGMT
                     STFTAPQLLQLRIIAITASAVSLIAGCLGMFFLSKMDKRRKVFRHDLIAFLIICDFLK
                     AFILMIYPMIILINNSVYATPAFFNTLGWFTAFAIEGADMAIMIFAIHFAILIFKPNW
                     KWRNKRSGNMEGGLYKKRSYIWPITALVPAILASLAFINYNKLNDDSDTTIILDNNNY
                     NFPDSPRQGGYKPWSAWCYLPPKPYWYKIVLSWGPRYFIIIFIFAVYLSIYIFITSES
                     KRIKAQIGDFNHNVLEEEKEKKKLFGLGHWGKAKWYFRSYFKLPLLHLLRNLKNFFTI
                     SFIDPNEETDDSGSSNGTFNFGESSNEIPTLFRKTNTGSDENVSASGGVRLLDYNSAK
                     PLDMSKYAMSEQPDLERNNPFDCENDITLNPSELVSKQKEHKVTFSVENEGLDTRKSS
                     MLGHQTFSCQNSLESPLAMYDNKNDNSDITSNIKEKGGIINNNSNNDDDDNNNNNDND
                     NDNNNSNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNSNNIKNNVDNNNTNPADNIPTL
                     SNEAFTPSQQFSQERVNNNADRCENSSFTNVQQHFQAQTYKQMKKRRAQIQKNLRAIF
                     IYPLSYIGIWLFPIIADALQYNHEIKHGPTMWVTYIDTCVRPLSCLVDVIVYLFKEKP
                     WNYSWAKTESKYLIEKYILKGELGEKEILKFCHSNWGKRGWYYRGKWKKRKCWKYSTN
                     PLKRILWFVERFFKQLFELKLHFSFYDNCDDFEYWENYYSAKDSNDNKRTESDETKTN
                     SSDRSLPSNSLELQAMLNNITAEEVEVPLFWRIIHHIPMLGGIDLDELNRLLKIRYNN
                     DHFSLPGLKFALNQNKSHDKHQDVSTNSMVKSSFFSSNIVTNDDENSIEEDKNLRYSD
                     ASASENYLVKPTIPGTTPDPIIEAQNDNDSSDSSGIDLIAFLRNGPL"
     gene            complement(<392659..>393912)
                     /gene="SLM3"
                     /locus_tag="YDL033C"
                     /gene_synonym="MTO2; MTU1"
                     /db_xref="GeneID:851529"
     mRNA            complement(<392659..>393912)
                     /gene="SLM3"
                     /locus_tag="YDL033C"
                     /gene_synonym="MTO2; MTU1"
                     /product="Slm3p"
                     /transcript_id="NM_001180092.1"
                     /db_xref="GI:296143328"
                     /db_xref="GeneID:851529"
     CDS             complement(392659..393912)
                     /gene="SLM3"
                     /locus_tag="YDL033C"
                     /gene_synonym="MTO2; MTU1"
                     /EC_number="2.8.1.-"
                     /note="tRNA-specific 2-thiouridylase; responsible for
                     2-thiolation of the wobble base of mitochondrial tRNAs;
                     human ortholog is implicated in myoclonus epilepsy
                     associated with ragged red fibers (MERRF)"
                     /codon_start=1
                     /product="Slm3p"
                     /protein_id="NP_010251.1"
                     /db_xref="GI:6320172"
                     /db_xref="SGD:S000002191"
                     /db_xref="GeneID:851529"
                     /translation="MLARYLNLIGRRSASPYRPQRLPAKFDNVIVAMSSGVDSSVAAA
                     LFAGEFPNTRGVYMQNWSESQSLDDPGKEPCYERDWRDVNRVAKHLNIRVDKVNFEQD
                     YWIDVFEPMLRGYSEGSTPNPDIGCNKFVKFGKLREWLDEKYGTGNYWLVTGHYARVM
                     QEMNGKGLFHLLRSIYRPKDQSYYLSQINSTVLSSLLLPIGHLTKPEVRDLAKYAGLP
                     TAEKPDSQGICFVNNSQHGKFKNFLKHYLPSSPGDIITVDPQSGAKTTWGRHDGLWSY
                     TIGQKVGISMPQADPNYQGTWFVSEKLRDTNEILIVRGRDNPALYSDTMRIENFSSLG
                     PREDTINAFQNTGALTLQFRSLQVPVQIKSCKLNRSADNLDITIHLASKQRAITPGQS
                     CCLYIDDRVLGSGPISHVNNNDTHA"
     gene            <394217..>397204
                     /gene="DBP10"
                     /locus_tag="YDL031W"
                     /db_xref="GeneID:851530"
     mRNA            <394217..>397204
                     /gene="DBP10"
                     /locus_tag="YDL031W"
                     /product="Dbp10p"
                     /transcript_id="NM_001180090.2"
                     /db_xref="GI:330443504"
                     /db_xref="GeneID:851530"
     CDS             394217..397204
                     /gene="DBP10"
                     /locus_tag="YDL031W"
                     /EC_number="3.6.4.13"
                     /note="Putative ATP-dependent RNA helicase of the DEAD-box
                     protein family; constituent of 66S pre-ribosomal
                     particles; essential protein involved in ribosome
                     biogenesis"
                     /codon_start=1
                     /product="Dbp10p"
                     /protein_id="NP_010253.2"
                     /db_xref="GI:330443505"
                     /db_xref="SGD:S000002189"
                     /db_xref="GeneID:851530"
                     /translation="MAGVQKRKRDLEDQDDNGSEEDDIAFDIANEIALNDSESDANDS
                     DSEVEADYGPNDVQDVIEYSSDEEEGVNNKKKAENKDIKKKKNSKKEIAAFPMLEMSD
                     DENNASGKTQTGDDEDDVNEYFSTNNLEKTKHKKGSFPSFGLSKIVLNNIKRKGFRQP
                     TPIQRKTIPLILQSRDIVGMARTGSGKTAAFILPMVEKLKSHSGKIGARAVILSPSRE
                     LAMQTFNVFKDFARGTELRSVLLTGGDSLEEQFGMMMTNPDVIIATPGRFLHLKVEMN
                     LDLKSVEYVVFDEADRLFEMGFQEQLNELLASLPTTRQTLLFSATLPNSLVDFVKAGL
                     VNPVLVRLDAETKVSENLEMLFLSSKNADREANLLYILQEIIKIPLATSEQLQKLQNS
                     NNEADSDSDDENDRQKKRRNFKKEKFRKQKMPAANELPSEKATILFVPTRHHVEYISQ
                     LLRDCGYLISYIYGTLDQHARKRQLYNFRAGLTSILVVTDVAARGVDIPMLANVINYT
                     LPGSSKIFVHRVGRTARAGNKGWAYSIVAENELPYLLDLELFLGKKILLTPMYDSLVD
                     VMKKRWIDEGKPEYQFQPPKLSYTKRLVLGSCPRLDVEGLGDLYKNLMSSNFDLQLAK
                     KTAMKAEKLYYRTRTSASPESLKRSKEIISSGWDAQNAFFGKNEEKEKLDFLAKLQNR
                     RNKETVFEFTRNPDDEMAVFMKRRRKQLAPIQRKATERRELLEKERMAGLSHSIEDEI
                     LKGDDGETGYTVSEDALKEFEDADQLLEAQENENKKKKKPKSFKDPTFFLSHYAPAGD
                     IQDKQLQITNGFANDAAQAAYDLNSDDKVQVHKQTATVKWDKKRKKYVNTQGIDNKKY
                     IIGESGQKIAASFRSGRFDDWSKARNLKPLKVGSRETSIPSNLLEDPSQGPAANGRTV
                     RGKFKHKQMKAPKMPDKHRDNYYSQKKKVEKALQSGISVKGYNNAPGLRSELKSTEQI
                     RKDRIIAEKKRAKNARPSKKRKF"
     gene            <397537..>399129
                     /gene="PRP9"
                     /locus_tag="YDL030W"
                     /db_xref="GeneID:851531"
     mRNA            <397537..>399129
                     /gene="PRP9"
                     /locus_tag="YDL030W"
                     /product="Prp9p"
                     /transcript_id="NM_001180089.1"
                     /db_xref="GI:296143330"
                     /db_xref="GeneID:851531"
     CDS             397537..399129
                     /gene="PRP9"
                     /locus_tag="YDL030W"
                     /note="Subunit of the SF3a splicing factor complex;
                     required for spliceosome assembly; acts after the
                     formation of the U1 snRNP-pre-mRNA complex"
                     /codon_start=1
                     /product="Prp9p"
                     /protein_id="NP_010254.1"
                     /db_xref="GI:6320174"
                     /db_xref="SGD:S000002188"
                     /db_xref="GeneID:851531"
                     /translation="MNLLETRRSLLEEMEIIENAIAERIQRNPELYYHYIQESSKVFP
                     DTKLPRSSLIAENKIYKFKKVKRKRKQIILQQHEINIFLRDYQEKQQTFNKINRPEET
                     QEDDKDLPNFERKLQQLEKELKNEDENFELDINSKKDKYALFSSSSDPSRRTNILSDR
                     ARDLDLNEIFTRDEQYGEYMELEQFHSLWLNVIKRGDCSLLQFLDILELFLDDEKYLL
                     TPPMDRKNDRYMAFLLKLSKYVETFFFKSYALLDAAAVENLIKSDFEHSYCRGSLRSE
                     AKGIYCPFCSRWFKTSSVFESHLVGKIHKKNESKRRNFVYSEYKLHRYLKYLNDEFSR
                     TRSFVERKLAFTANERMAEMDILTQKYEAPAYDSTEKEGAEQVDGEQRDGQLQEEHLS
                     GKSFDMPLGPDGLPMPYWLYKLHGLDREYRCEICSNKVYNGRRTFERHFNEERHIYHL
                     RCLGIEPSSVFKGITKIKEAQELWKNMQGQSQLTSIAAVPPKPNPSQLKVPTELELEE
                     EDEEGNVMSKKVYDELKKQGLV"
     gene            <399340..>400638
                     /gene="ARP2"
                     /locus_tag="YDL029W"
                     /gene_synonym="ACT2"
                     /db_xref="GeneID:851532"
     mRNA            join(<399340..399361,399485..>400638)
                     /gene="ARP2"
                     /locus_tag="YDL029W"
                     /gene_synonym="ACT2"
                     /product="actin-related protein 2"
                     /transcript_id="NM_001180088.1"
                     /db_xref="GI:296143331"
                     /db_xref="GeneID:851532"
     CDS             join(399340..399361,399485..400638)
                     /gene="ARP2"
                     /locus_tag="YDL029W"
                     /gene_synonym="ACT2"
                     /note="Essential component of the Arp2/3 complex; Arp2/3
                     is a highly conserved actin nucleation center required for
                     the motility and integrity of actin patches; involved in
                     endocytosis and membrane growth and polarity; required for
                     efficient Golgi-to-ER trafficking in COPI mutants"
                     /codon_start=1
                     /product="actin-related protein 2"
                     /protein_id="NP_010255.1"
                     /db_xref="GI:6320175"
                     /db_xref="SGD:S000002187"
                     /db_xref="GeneID:851532"
                     /translation="MDPHNPIVLDQGTGFVKIGRAGENFPDYTFPSIVGRPILRAEER
                     ASVATPLKDIMIGDEASEVRSYLQISYPMENGIIKNWTDMELLWDYAFFEQMKLPSTS
                     NGKILLTEPPMNPLKNREKMCEVMFEKYDFGGVYVAIQAVLALYAQGLSSGVVVDSGD
                     GVTHIVPVYESVVLSHLTRRLDVAGRDVTRHLIDLLSRRGYAFNRTADFETVRQIKEK
                     LCYVSYDLDLDTKLARETTALVESYELPDGRTIKVGQERFEAPECLFQPGLVDVEQPG
                     VGELLFNTVQSADVDIRSSLYKAIVLSGGSSMYPGLPSRLEKELKQLWFSRVLHNDPS
                     RLDKFKVRIEDPPRRKHMVFIGGAVLASIMADKDHMWLSKQEWQESGPSAMTKFGPR"
     gene            complement(<400997..>403291)
                     /gene="MPS1"
                     /locus_tag="YDL028C"
                     /gene_synonym="PAC8; RPK1"
                     /db_xref="GeneID:851533"
     mRNA            complement(<400997..>403291)
                     /gene="MPS1"
                     /locus_tag="YDL028C"
                     /gene_synonym="PAC8; RPK1"
                     /product="Mps1p"
                     /transcript_id="NM_001180087.2"
                     /db_xref="GI:330443506"
                     /db_xref="GeneID:851533"
     CDS             complement(400997..403291)
                     /gene="MPS1"
                     /locus_tag="YDL028C"
                     /gene_synonym="PAC8; RPK1"
                     /EC_number="2.7.12.2"
                     /note="Dual-specificity kinase; autophosphorylation
                     required for function; required for spindle pole body
                     (SPB) duplication and spindle checkpoint function;
                     contributes to bi-orientation by promoting formation of
                     force-generating kinetochore-microtubule attachments in
                     meiosis I; substrates include SPB proteins Spc42p,
                     Spc110p, and Spc98p, mitotic exit network protein Mob1p,
                     kinetochore protein Cnn1p, and checkpoint protein Mad1p;
                     substrate of APCC(Cdh1); similar to human Mps1p"
                     /codon_start=1
                     /product="Mps1p"
                     /protein_id="NP_010256.2"
                     /db_xref="GI:330443507"
                     /db_xref="SGD:S000002186"
                     /db_xref="GeneID:851533"
                     /translation="MSTNSFHDYVDLKSRTNTRQFSDDEEFTTPPKLSNFGSALLSHT
                     EKTSASEILSSHNNDKIANRLEEMDRSSSRSHPPPSMGNLTSGHTSTSSHSTLFGRYL
                     RNNHQTSMTTMNTSDIEINVGNSLDKSFERIRNLRQNMKEDITAKYAERRSKRFLISN
                     RTTKLGPAKRAMTLTNIFDEDVPNSPNQPINARETVELPLEDSHQTNFKETKRNTDYD
                     SIDFGDLNPIQYIKKHNLPTSDLPLISQIYFDKQREENRQAALRKHSSRELLYKSRSS
                     SSSLSSNNLLANKDNSITSNNGSQPRRKVSTGSSSSKSSIEIRRALKENIDTSNNSNF
                     NSPIHKIYKGISRNKDSDSEKREVLRNISINANHADNLLQQENKRLKRSLDDAITNEN
                     INSKNLEVFYHRPAPKPPVTKKVEIVEPAKSASLSNNRNIITVNDSQYEKIELLGRGG
                     SSRVYKVKGSGNRVYALKRVSFDAFDDSSIDGFKGEIELLEKLKDQKRVIQLLDYEMG
                     DGLLYLIMECGDHDLSQILNQRSGMPLDFNFVRFYTKEMLLCIKVVHDAGIVHSDLKP
                     ANFVLVKGILKIIDFGIANAVPEHTVNIYRETQIGTPNYMAPEALVAMNYTQNSENQH
                     EGNKWKVGRPSDMWSCGCIIYQMIYGKPPYGSFQGQNRLLAIMNPDVKIPFPEHTSNN
                     EKIPKSAIELMKACLYRNPDKRWTVDKVLSSTFLQPFMISGSIMEDLIRNAVRYGSEK
                     PHISQDDLNDVVDTVLRKFADYKI"
     gene            complement(<403695..>404957)
                     /locus_tag="YDL027C"
                     /db_xref="GeneID:851535"
     mRNA            complement(<403695..>404957)
                     /locus_tag="YDL027C"
                     /product="hypothetical protein"
                     /transcript_id="NM_001180086.1"
                     /db_xref="GI:296143333"
                     /db_xref="GeneID:851535"
     CDS             complement(403695..404957)
                     /locus_tag="YDL027C"
                     /note="hypothetical protein; the authentic, non-tagged
                     protein is detected in highly purified mitochondria in
                     high-throughput studies; YDL027C is not an essential gene"
                     /codon_start=1
                     /product="hypothetical protein"
                     /protein_id="NP_010257.1"
                     /db_xref="GI:6320178"
                     /db_xref="SGD:S000002185"
                     /db_xref="GeneID:851535"
                     /translation="MFKVPVGLASRTRELMNSVTLNSLNNGKGFNMYLPGILRAFPKP
                     VPSAITSPAIPKYRGESFQFRKLSCISSNYCSTTHQFLSSLKSSTSRLVGKRAFHSSR
                     RAEIKFIFSSKSPKNGNKPFVKVYKVSPFFIIFATASIFTFILTSTIVVIPLIFHFFF
                     PLLIMFFFFKQFKKWQKNIFYKDVLTSLPKTKLKITLPTMRSLQLQPMVQSWKEISSR
                     MGIPNEFAKGLNVDLVKQEETRKQFLSFLQKRVLESFTKNELGIRSYFLGDSVEKWIK
                     ESYDLELDIDNCRSELRKFQTFIFSSVRYKLYLDSMKNLPLNPSKKLEGKKHIADVYV
                     IILDESFPAIMFNGGAYSKADFFKILQESETSNSSKTLNTIIAIKSVNTLLSKHFVIT
                     TNGDSGEFFSKYNISKINDKNTEYTLKE"
     gene            complement(<405344..>407206)
                     /gene="RTK1"
                     /locus_tag="YDL025C"
                     /db_xref="GeneID:851536"
     mRNA            complement(<405344..>407206)
                     /gene="RTK1"
                     /locus_tag="YDL025C"
                     /product="Rtk1p"
                     /transcript_id="NM_001180084.1"
                     /db_xref="GI:296143334"
                     /db_xref="GeneID:851536"
     CDS             complement(405344..407206)
                     /gene="RTK1"
                     /locus_tag="YDL025C"
                     /EC_number="2.7.11.1"
                     /note="Putative protein kinase, potentially phosphorylated
                     by Cdc28p; interacts with ribosome biogenesis factors,
                     Cka2, Gus1 and Arc1; protein abundance increases in
                     response to DNA replication stress"
                     /codon_start=1
                     /product="Rtk1p"
                     /protein_id="NP_010259.1"
                     /db_xref="GI:6320179"
                     /db_xref="SGD:S000002183"
                     /db_xref="GeneID:851536"
                     /translation="MVKETPLHSSSSTSLSSLFRPTKLKNLSAKIFNGGGNQSYSKTD
                     DVSRSSSRSSKKNTDSDQEDQIKYNKPNDRRSTIGKSPQGNGALSKESHVVASSTLTG
                     ISPTSAKKAPIDYSPSRPLPNNHNPVRTGHTVPHLPHSIHNPINYIHQGSKDAFHHPH
                     PVRSTAHSNISTVSSAKSDTPSSNLSYQAHMHPVEILQKQIEDKHFMDSQASTPGSVE
                     LQHNSSSGSDDTSSRKKKSLRLTRFFKKIHNDYHDNHHHHHHHNRGSTPTKPKLNLNT
                     NENIVESNGKALYETDNPVELLEKYGIPGRKLGEGASGSVSVVERTDGKLFACKMFRK
                     PHLNNEGTNQSQLANYSKKVTTEFCIGSTLHHENIVETLDMLTEGDTYLLVMEYAPYD
                     FFNLVMSNLMTQDEVNCYFKQLCHGVNYLHSMGLAHRDLKLDNCVVTKDGILKLIDFG
                     SAVVFQYPYEDTIVKSHGIVGSDPYLAPELLKQTSYDPRVADVWSIAIIFYCMVLKRF
                     PWKAPKKSFNSFRLFTEEPEDEDDIVRGPNKILRLLPRHSRTIIGRMLALEPKQRVLM
                     NDVVKDDWLVSVPSCEVDPTSGDLVEKPKNHKHHLVTEEELNELTKQHGNKDSN"
     rep_origin      408075..408316
                     /note="ARS414;
                     Autonomously Replicating Sequence"
                     /db_xref="SGD:S000118433"
     gene            complement(<408451..>409857)
                     /gene="DIA3"
                     /locus_tag="YDL024C"
                     /db_xref="GeneID:851537"
     mRNA            complement(<408451..>409857)
                     /gene="DIA3"
                     /locus_tag="YDL024C"
                     /product="Dia3p"
                     /transcript_id="NM_001180083.1"
                     /db_xref="GI:296143335"
                     /db_xref="GeneID:851537"
     CDS             complement(408451..409857)
                     /gene="DIA3"
                     /locus_tag="YDL024C"
                     /EC_number="3.1.3.2"
                     /note="hypothetical protein; involved in invasive and
                     pseudohyphal growth"
                     /codon_start=1
                     /product="Dia3p"
                     /protein_id="NP_010260.1"
                     /db_xref="GI:6320180"
                     /db_xref="SGD:S000002182"
                     /db_xref="GeneID:851537"
                     /translation="MVKPVIFAICLGVLLSKALSIPLRSFADIELIGSQKSLFPFLGG
                     SAPYFSFPANYGIPTDIPEGCRLTQVQMIGRHGERYPTRSEAKDIFEVWYKISNYTGK
                     YEGSLSFLNNGYEFFIPDESLLEMETTLQNSIDVLNPYTGEMNAKRHAREFLAKYGKL
                     MENCTNFPIFTTNSKRIYDTAQYFAEALGDGFNISLQTLSENSSSGANTLAAKSSCPN
                     WNSNANNDILMSYSRDYLENISDRLNDENKGLNLSRKDAAALFSWCAFELNAKGYSNI
                     CDIFSAAELIHYSYETDLTSFYQNGPGYKLIKSIGANLFNATVKLIRQSAHLDQKVWL
                     SFTHDTDILNYLTTAGLIDDTRNLTTNHVPFRDHSYHRSWYIPQGARVYTEKFQCSND
                     SYVRYVVNDAVVPIESCSSGPGFSCEEGTFYEYAKDRLRGVSFYEDCDVSKVSKEKEL
                     TFYWDWNTTRYNASLVNQ"
     gene            complement(<409808..>410056)
                     /locus_tag="YDL022C-A"
                     /db_xref="GeneID:13393611"
     mRNA            complement(<409808..>410056)
                     /locus_tag="YDL022C-A"
                     /product="hypothetical protein"
                     /transcript_id="NM_001270741.1"
                     /db_xref="GI:398364786"
                     /db_xref="GeneID:13393611"
     CDS             complement(409808..410056)
                     /locus_tag="YDL022C-A"
                     /note="hypothetical protein; partially overlaps the
                     verified gene DIA3; identified by fungal homology and
                     RT-PCR; mRNA identified as translated by ribosome
                     profiling data"
                     /codon_start=1
                     /product="hypothetical protein"
                     /protein_id="NP_001257670.1"
                     /db_xref="GI:398364787"
                     /db_xref="SGD:S000028537"
                     /db_xref="GeneID:13393611"
                     /translation="MYYLVPKTTYGNLQCSSLAMTFHERGESGDVLSCACRLYLYIMP
                     LFFNTFLRQKYFQLCSNTPYRNNGEARYFCHLFRCSII"
     gene            410379..410451
                     /locus_tag="tA(AGC)D"
                     /db_xref="GeneID:851538"
     tRNA            410379..410451
                     /locus_tag="tA(AGC)D"
                     /product="tRNA-Ala"
                     /note="Alanine tRNA (tRNA-Ala), predicted by tRNAscan-SE
                     analysis; one of 11 nuclear tRNA genes containing the
                     tDNA-anticodon AGC (converted to IGC in the mature tRNA),
                     decodes GCU and GCC codons into alanine, one of 16 nuclear
                     tRNAs for alanine"
                     /db_xref="SGD:S000006510"
                     /db_xref="GeneID:851538"
     gene            <411825..>413000
                     /gene="GPD1"
                     /locus_tag="YDL022W"
                     /gene_synonym="DAR1; HOR1; OSG1; OSR5"
                     /db_xref="GeneID:851539"
     mRNA            <411825..>413000
                     /gene="GPD1"
                     /locus_tag="YDL022W"
                     /gene_synonym="DAR1; HOR1; OSG1; OSR5"
                     /product="glycerol-3-phosphate dehydrogenase (NAD(+))
                     GPD1"
                     /transcript_id="NM_001180081.1"
                     /db_xref="GI:296143336"
                     /db_xref="GeneID:851539"
     CDS             411825..413000
                     /gene="GPD1"
                     /locus_tag="YDL022W"
                     /gene_synonym="DAR1; HOR1; OSG1; OSR5"
                     /EC_number="1.1.1.8"
                     /note="NAD-dependent glycerol-3-phosphate dehydrogenase;
                     key enzyme of glycerol synthesis, essential for growth
                     under osmotic stress; expression regulated by
                     high-osmolarity glycerol response pathway; protein
                     abundance increases in response to DNA replication stress;
                     constitutively inactivated via phosphorylation by the
                     protein kinases YPK1 and YPK2, dephosphorylation increases
                     catalytic activity; GPD1 has a paralog, GPD2, that arose
                     from the whole genome duplication"
                     /codon_start=1
                     /product="glycerol-3-phosphate dehydrogenase (NAD(+))
                     GPD1"
                     /protein_id="NP_010262.1"
                     /db_xref="GI:6320181"
                     /db_xref="SGD:S000002180"
                     /db_xref="GeneID:851539"
                     /translation="MSAAADRLNLTSGHLNAGRKRSSSSVSLKAAEKPFKVTVIGSGN
                     WGTTIAKVVAENCKGYPEVFAPIVQMWVFEEEINGEKLTEIINTRHQNVKYLPGITLP
                     DNLVANPDLIDSVKDVDIIVFNIPHQFLPRICSQLKGHVDSHVRAISCLKGFEVGAKG
                     VQLLSSYITEELGIQCGALSGANIATEVAQEHWSETTVAYHIPKDFRGEGKDVDHKVL
                     KALFHRPYFHVSVIEDVAGISICGALKNVVALGCGFVEGLGWGNNASAAIQRVGLGEI
                     IRFGQMFFPESREETYYQESAGVADLITTCAGGRNVKVARLMATSGKDAWECEKELLN
                     GQSAQGLITCKEVHEWLETCGSVEDFPLFEAVYQIVYNNYPMKNLPDMIEELDLHED"
     gene            <413953..>414888
                     /gene="GPM2"
                     /locus_tag="YDL021W"
                     /db_xref="GeneID:851541"
     mRNA            <413953..>414888
                     /gene="GPM2"
                     /locus_tag="YDL021W"
                     /product="phosphoglycerate mutase family protein GPM2"
                     /transcript_id="NM_001180080.1"
                     /db_xref="GI:296143337"
                     /db_xref="GeneID:851541"
     CDS             413953..414888
                     /gene="GPM2"
                     /locus_tag="YDL021W"
                     /EC_number="5.4.2.11"
                     /note="Homolog of Gpm1p phosphoglycerate mutase; converts
                     3-phosphoglycerate to 2-phosphoglycerate in glycolysis;
                     may be non-functional; GPM2 has a paralog, GPM3, that
                     arose from the whole genome duplication"
                     /codon_start=1
                     /product="phosphoglycerate mutase family protein GPM2"
                     /protein_id="NP_010263.1"
                     /db_xref="GI:6320183"
                     /db_xref="SGD:S000002179"
                     /db_xref="GeneID:851541"
                     /translation="MTASTPSNVMTLFLLRHGQSELNHENIFCGWIDAKLTEKGKEQA
                     RHSAELIEQYCKANNLRLPQIGYTSRLIRTQQTIETMCEEFKLKPQLQVVYDFNKIKL
                     GDEFGSDDKDNMKIPILQTWRLNERHYGSWQGQRKPNVLKEYGKDKYMFIRRDYEGKP
                     PPVDLDREMIQQENEKGSSTGYEFKEPNRQIKYELECSNHDIVLPDSESLREVVYRLN
                     PFLQNVILKLANQYDESSCLIVGHGSSVRSLLKILEGISDDDIKNVDIPNGIPLVVEL
                     DKNNGLKFIRKFYLDPESAKINAEKVRNEGFIKNP"
     gene            complement(<415113..>416708)
                     /gene="RPN4"
                     /locus_tag="YDL020C"
                     /gene_synonym="SON1; UFD5"
                     /db_xref="GeneID:851542"
     mRNA            complement(<415113..>416708)
                     /gene="RPN4"
                     /locus_tag="YDL020C"
                     /gene_synonym="SON1; UFD5"
                     /product="Rpn4p"
                     /transcript_id="NM_001180079.3"
                     /db_xref="GI:398364804"
                     /db_xref="GeneID:851542"
     CDS             complement(415113..416708)
                     /gene="RPN4"
                     /locus_tag="YDL020C"
                     /gene_synonym="SON1; UFD5"
                     /note="Transcription factor that stimulates expression of
                     proteasome genes; Rpn4p levels are in turn regulated by
                     the 26S proteasome in a negative feedback control
                     mechanism; RPN4 is transcriptionally regulated by various
                     stress responses; relative distribution to the nucleus
                     increases upon DNA replication stress"
                     /codon_start=1
                     /product="Rpn4p"
                     /protein_id="NP_010264.3"
                     /db_xref="GI:398364805"
                     /db_xref="SGD:S000002178"
                     /db_xref="GeneID:851542"
                     /translation="MASTELSLKRTLTDILEDELYHTNPGHSQFTSHYQNYHPNASIT
                     PYKLVNKNKENNTFTWNHSLQHQNESSAASIPPQQTYHFPIFNKYADPTLTTTTSFTT
                     SEATANDRQINNVHLIPNEIKGASETPLQKTVNLKNIMKVSDPYVPTRNTFNYDVKIS
                     NDFFDNGDNLYGNDEEVLFYEDNYNPKMQWSLQDNSAAINNEDARAIFNNEFDSDDDD
                     ISDDEEDEIEENCLQQEQHQEEPLLSLDVTPISMFGSDQKTGRAKSSSHLFNEYSYVD
                     SNMDSISSVVSEDLLDERGHEKIEDEDEDNDLDEDDIYDISLLKNRRKQSFVLNKNTI
                     DFERFPSPSTSANVPSTATTGKRKPAKSSSNRSCVSNSNENGTLERIKKPTSAVVSSN
                     ASRRKLINYTKKHLSSHSSTNSNSKPSTASPSAHTSSSDGNNEIFTCQIMNLITNEPC
                     GAQFSRSYDLTRHQNTIHAKRKIVFRCSECIKILGSEGYQKTFSRLDALTRHIKSKHE
                     DLSLEQRQEVTKFAKANIGYVMG"
     gene            complement(<417663..>421514)
                     /gene="OSH2"
                     /locus_tag="YDL019C"
                     /db_xref="GeneID:851543"
     mRNA            complement(<417663..>421514)
                     /gene="OSH2"
                     /locus_tag="YDL019C"
                     /product="oxysterol-binding protein related protein OSH2"
                     /transcript_id="NM_001180078.1"
                     /db_xref="GI:296143339"
                     /db_xref="GeneID:851543"
     CDS             complement(417663..421514)
                     /gene="OSH2"
                     /locus_tag="YDL019C"
                     /note="Member of an oxysterol-binding protein family with
                     seven members; in S. cerevisiae, family members have
                     overlapping, redundant functions in sterol metabolism and
                     collectively perform a function essential for viability;
                     OSH2 has a paralog, SWH1, that arose from the whole genome
                     duplication"
                     /codon_start=1
                     /product="oxysterol-binding protein related protein OSH2"
                     /protein_id="NP_010265.1"
                     /db_xref="GI:6320185"
                     /db_xref="SGD:S000002177"
                     /db_xref="GeneID:851543"
                     /translation="MSREDLSIAEDLNQVSKPLLKVKLLEVLGQGDFKHLKALVDNEF
                     QPKDDPSVQQVLNLILHYAVQVAPILLIKEIVAHWVDQVGDEKSSSKSDDGIHLDLNY
                     QDENGNTPLHLAAAQSRSDVISFLLSQKSINDCVKNKAHQQPLDMCKDLNVAQMIQLK
                     RDDYFLETVHSLRAAMNKRDFSKLDSIWKNPRNLNLLDINGIDPETGTTLLYEYSQKK
                     DIEMCQWLLKHGAEATVKDGKGRSPLDLVKNIKLPAKPSNNVTPEIKLKNLLEKNLRE
                     QAIVHEDVASSKPPTYKGFLKKWTNFAHGYKLRWFILSGDGNLSYYKDQSHVDRPRGT
                     LKVSTCRLHIDSSEKLNFELLGGITGTTRWRLKGNHPIETTRWVNAIQSAIRFAKDKE
                     ILNKKKAVPPSLALKNKSPALISHSKTQGSLPEASQYYQHTLHKEVIQPSSVSLYRRP
                     SNNLSVVSSEIQLNDNLTESGKRFVSKMIENRLDGSKTPVGVHTGSALQRVRSSNTLK
                     SNRSMQSGSGVASPIDKVPNGANLSQSNTTTGSTASLSDNNYIDNFEGDEANSDDEEE
                     DLGINFDRDEEYIKAQYGPYKEKLDMYEQAISIELSSLIELIEQEEPSPEVWLTIKKS
                     LINTSTIFGKLKDLTYKRDKRLVDMVSKQGDVNNVWVQSVKELEMELSNKTERLASID
                     KERRGLKKILHKKLLESHATAGNKESLENDKEQESDTTASTLGQIAKFISATKEEDEA
                     SDADEFYDAAELVDEVTELTEAHPEISTAAAPKHAPPPVPNETDNDSQYVQDEKSKIE
                     SNVEKTSQKFEKQNNLVTEDEPKTDQSLKNFKAEDKESQVKEKTKEIASSVIGEKTIV
                     AVTTVQKRKEEYLLKEGSYLGYEDGIRKRLSMDKDDRPKISLWAVLKSMVGKDMTRMT
                     LPVTFNEPTSLLQRVAEDLEYSELLDQAATFEDSTLRTLYVAAFTASSYASTTKRVAK
                     PFNPLLGETFEYSRPDKQYRFFTEQVSHHPPISATWTESPRWDFWGESFVDTKFNGRS
                     FNVKHLGLWHIKLRPNDNEKEELYTWKKPNNTVIGILIGNPQVDNHGEVNVVNHTTGD
                     HCKLYFKARGWRSSGAYEITGEVYNKKKQKVWILGGHWNEAIFAKKVVKDGDLSLEKT
                     RTAASAGNGPTDDGTKFLIWKANDRPEEPFNLTPFAITLNAPQPHLLPWLPPTDTRLR
                     PDQRAMEDGRYDEAGDEKFRVEEKQRAARRKREENNLEYHPQWFVRDTHPITKAKYWR
                     YTGKYWVKRRDHDLKDCGDIF"
     gene            complement(<422833..>423510)
                     /gene="ERP3"
                     /locus_tag="YDL018C"
                     /db_xref="GeneID:851544"
     mRNA            complement(<422833..>423510)
                     /gene="ERP3"
                     /locus_tag="YDL018C"
                     /product="Erp3p"
                     /transcript_id="NM_001180077.1"
                     /db_xref="GI:296143340"
                     /db_xref="GeneID:851544"
     CDS             complement(422833..423510)
                     /gene="ERP3"
                     /locus_tag="YDL018C"
                     /note="Protein with similarity to Emp24p and Erv25p;
                     member of the p24 family involved in ER to Golgi
                     transport"
                     /codon_start=1
                     /product="Erp3p"
                     /protein_id="NP_010266.1"
                     /db_xref="GI:6320186"
                     /db_xref="SGD:S000002176"
                     /db_xref="GeneID:851544"
                     /translation="MSNLCVLFFQFFFLAQFFAEASPLTFELNKGRKECLYTLTPEID
                     CTISYYFAVQQGESNDFDVNYEIFAPDDKNKPIIERSGERQGEWSFIGQHKGEYAICF
                     YGGKAHDKIVDLDFKYNCERQDDIRNERRKARKAQRNLRDSKTDPLQDSVENSIDTIE
                     RQLHVLERNIQYYKSRNTRNHHTVCSTEHRIVMFSIYGILLIIGMSCAQIAILEFIFR
                     ESRKHNV"
     gene            <424209..>425732
                     /gene="CDC7"
                     /locus_tag="YDL017W"
                     /gene_synonym="LSD6; SAS1"
                     /db_xref="GeneID:851545"
     mRNA            <424209..>425732
                     /gene="CDC7"
                     /locus_tag="YDL017W"
                     /gene_synonym="LSD6; SAS1"
                     /product="Cdc7p"
                     /transcript_id="NM_001180076.3"
                     /db_xref="GI:398364828"
                     /db_xref="GeneID:851545"
     CDS             424209..425732
                     /gene="CDC7"
                     /locus_tag="YDL017W"
                     /gene_synonym="LSD6; SAS1"
                     /EC_number="2.7.11.1"
                     /note="DDK (Dbf4-dependent kinase) catalytic subunit;
                     required for origin firing and replication fork
                     progression in mitotic S phase through phosphorylation of
                     Mcm2-7p complexes and Cdc45p; kinase activity correlates
                     with cyclical DBF4 expression; required for pre-meiotic
                     DNA replication, meiotic DSB formation, recruitment of the
                     monopolin complex to kinetochores during meiosis I and as
                     a gene-specific regulator of the meiosis-specific
                     transcription factor Ndt80p"
                     /codon_start=1
                     /product="Cdc7p"
                     /protein_id="NP_010267.3"
                     /db_xref="GI:398364829"
                     /db_xref="SGD:S000002175"
                     /db_xref="GeneID:851545"
                     /translation="MTSKTKNIDDIPPEIKEEMIQLYHDLPGIENEYKLIDKIGEGTF
                     SSVYKAKDITGKITKKFASHFWNYGSNYVALKKIYVTSSPQRIYNELNLLYIMTGSSR
                     VAPLCDAKRVRDQVIAVLPYYPHEEFRTFYRDLPIKGIKKYIWELLRALKFVHSKGII
                     HRDIKPTNFLFNLELGRGVLVDFGLAEAQMDYKSMISSQNDYDNYANTNHDGGYSMRN
                     HEQFCPCIMRNQYSPNSHNQTPPMVTIQNGKVVHLNNVNGVDLTKGYPKNETRRIKRA
                     NRAGTRGFRAPEVLMKCGAQSTKIDIWSVGVILLSLLGRRFPMFQSLDDADSLLELCT
                     IFGWKELRKCAALHGLGFEASGLIWDKPNGYSNGLKEFVYDLLNKECTIGTFPEYSVA
                     FETFGFLQQELHDRMSIEPQLPDPKTNMDAVDAYELKKYQEEIWSDHYWCFQVLEQCF
                     EMDPQKRSSAEDLLKTPFFNELNENTYLLDGESTDEDDVVSSSEADLLDKDVLLISE"
     gene            complement(<426002..>426934)
                     /gene="TSC13"
                     /locus_tag="YDL015C"
                     /db_xref="GeneID:851547"
     mRNA            complement(<426002..>426934)
                     /gene="TSC13"
                     /locus_tag="YDL015C"
                     /product="trans-2-enoyl-CoA reductase (NADPH) TSC13"
                     /transcript_id="NM_001180074.1"
                     /db_xref="GI:296143342"
                     /db_xref="GeneID:851547"
     CDS             complement(426002..426934)
                     /gene="TSC13"
                     /locus_tag="YDL015C"
                     /EC_number="1.3.1.93"
                     /note="Enoyl reductase; catalyzes the last step in each
                     cycle of very long chain fatty acid elongation; localizes
                     to the ER, highly enriched in a structure marking
                     nuclear-vacuolar junctions; coimmunoprecipitates with
                     elongases Fen1p and Sur4p; protein increases in abundance
                     and relative distribution to ER foci increases upon DNA
                     replication stress"
                     /codon_start=1
                     /product="trans-2-enoyl-CoA reductase (NADPH) TSC13"
                     /protein_id="NP_010269.1"
                     /db_xref="GI:6320189"
                     /db_xref="SGD:S000002173"
                     /db_xref="GeneID:851547"
                     /translation="MPITIKSRSKGLRDTEIDLSKKPTLDDVLKKISANNHNISKYRI
                     RLTYKKESKQVPVISESFFQEEADDSMEFFIKDLGPQISWRLVFFCEYLGPVLVHSLF
                     YYLSTIPTVVDRWHSASSDYNPFLNRVAYFLILGHYGKRLFETLFVHQFSLATMPIFN
                     LFKNCFHYWVLSGLISFGYFGYGFPFGNAKLFKYYSYLKLDDLSTLIGLFVLSELWNF
                     YCHIKLRLWGDYQKKHGNAKIRVPLNQGIFNLFVAPNYTFEVWSWIWFTFVFKFNLFA
                     VLFLTVSTAQMYAWAQKKNKKYHTRRAFLIPFVF"
     gene            <427364..>428347
                     /gene="NOP1"
                     /locus_tag="YDL014W"
                     /gene_synonym="LOT3"
                     /db_xref="GeneID:851548"
     mRNA            <427364..>428347
                     /gene="NOP1"
                     /locus_tag="YDL014W"
                     /gene_synonym="LOT3"
                     /product="rRNA methyltransferase NOP1"
                     /transcript_id="NM_001180073.1"
                     /db_xref="GI:296143343"
                     /db_xref="GeneID:851548"
     CDS             427364..428347
                     /gene="NOP1"
                     /locus_tag="YDL014W"
                     /gene_synonym="LOT3"
                     /EC_number="2.1.1.-"
                     /note="Histone glutamine methyltransferase, modifies H2A
                     at Q105 in nucleolus; component of the small subunit
                     processome complex, which is required for processing of
                     pre-18S rRNA; ortholog of mammalian fibrillarin"
                     /codon_start=1
                     /product="rRNA methyltransferase NOP1"
                     /protein_id="NP_010270.1"
                     /db_xref="GI:6320190"
                     /db_xref="SGD:S000002172"
                     /db_xref="GeneID:851548"
                     /translation="MSFRPGSRGGSRGGSRGGFGGRGGSRGGARGGSRGGFGGRGGSR
                     GGARGGSRGGFGGRGGSRGGARGGSRGGRGGAAGGARGGAKVVIEPHRHAGVYIARGK
                     EDLLVTKNMAPGESVYGEKRISVEEPSKEDGVPPTKVEYRVWNPFRSKLAAGIMGGLD
                     ELFIAPGKKVLYLGAASGTSVSHVSDVVGPEGVVYAVEFSHRPGRELISMAKKRPNII
                     PIIEDARHPQKYRMLIGMVDCVFADVAQPDQARIIALNSHMFLKDQGGVVISIKANCI
                     DSTVDAETVFAREVQKLREERIKPLEQLTLEPYERDHCIVVGRYMRSGLKK"
     gene            <429067..>430926
                     /gene="SLX5"
                     /locus_tag="YDL013W"
                     /gene_synonym="HEX3; ULS2"
                     /db_xref="GeneID:851549"
     mRNA            <429067..>430926
                     /gene="SLX5"
                     /locus_tag="YDL013W"
                     /gene_synonym="HEX3; ULS2"
                     /product="SUMO-targeted ubiquitin ligase complex subunit
                     SLX5"
                     /transcript_id="NM_001180072.3"
                     /db_xref="GI:398364838"
                     /db_xref="GeneID:851549"
     CDS             429067..430926
                     /gene="SLX5"
                     /locus_tag="YDL013W"
                     /gene_synonym="HEX3; ULS2"
                     /EC_number="6.3.2.-"
                     /note="Subunit of the Slx5-Slx8 SUMO-targeted ubiquitin
                     ligase complex; stimulated by SUMO-modified substrates;
                     contains a RING domain and two SIMs (SUMO-interacting
                     motifs); forms SUMO-dependent nuclear foci, including DNA
                     repair centers; the SUMO-targeted ubiquitin ligase complex
                     is also known as the STUbL complex"
                     /codon_start=1
                     /product="SUMO-targeted ubiquitin ligase complex subunit
                     SLX5"
                     /protein_id="NP_010271.3"
                     /db_xref="GI:398364839"
                     /db_xref="SGD:S000002171"
                     /db_xref="GeneID:851549"
                     /translation="MHSDTNGRTKSNNSPSDNNPNETVILIDSDKEEDASIREANLPV
                     RLYPDRRVGRRRDALNRFVRSDSRSRNSQRTHITASSERPDFQANNDDITIIREVGRF
                     FGDDGPIDPSAHYVDLDQEPGSETLETPRTIQVDNTNGYLNDNGNNNESDDGLTIVEE
                     RTTRPRVTLNLPGGERLEVTATTTDIPIRRSFEFQEDLGASRRQLLRRSATRARNLFV
                     DRSDENDEDWTDDTHNLPEAIQRARRESRMRMSRRIAERQRRVQQQRVSSDENISTSI
                     RLQSIRERIQSYTPDIRSAFHRAESLHEFRSILQNVAPITLQECEEELMALFTEFRNQ
                     LLQNWAIDRVRNTQEEALRLHREALERQERTAGRVFHRGTLRESITNYLNFNGEDGFL
                     SRLWSGPALSDADEERHTQNIIDMIQEREERERDVVMKNLMNKTRAQQEEFEARAASL
                     PEGYSASFDTTPKMKLDITKNGKEETIIVTDDDLAKTLEDIPVCCLCGAELGVGIPDD
                     FTGISQKDRGVSFEGLVSKYKFHCPYQTLARPSMLDRDLSKRTFIASCGHAFCGRCFA
                     RIDNAKKKSKMPKKKLAQLKGSAHPDNYGPKLCPADSCKKLIRSRGRLKEVYF"
     gene            complement(<431108..>431517)
                     /locus_tag="YDL012C"
                     /db_xref="GeneID:851550"
     mRNA            complement(join(<431108..431386,431473..>431517))
                     /locus_tag="YDL012C"
                     /product="hypothetical protein"
                     /transcript_id="NM_001180071.1"
                     /db_xref="GI:296143345"
                     /db_xref="GeneID:851550"
     CDS             complement(join(431108..431386,431473..431517))
                     /locus_tag="YDL012C"
                     /note="Tail-anchored plasma membrane protein with a
                     conserved CYSTM module; possibly involved in response to
                     stress; may contribute to non-homologous end-joining
                     (NHEJ) based on ydl012c htz1 double null phenotype;
                     YDL012C has a paralog, YBR016W, that arose from the whole
                     genome duplication"
                     /codon_start=1
                     /product="hypothetical protein"
                     /protein_id="NP_010272.1"
                     /db_xref="GI:6320192"
                     /db_xref="SGD:S000002170"
                     /db_xref="GeneID:851550"
                     /translation="MSAQDYYGNSASKQSYSRPSAPPPGYETASRGYAPSQSQQNYYP
                     PQQQQQQYQQQPQYYQQQQPQYYQQHPQQPIYVQQQPASSGNEDCLAGCLAGLCLCCT
                     LDMLF"
     gene            <432330..>433025
                     /gene="GRX6"
                     /locus_tag="YDL010W"
                     /db_xref="GeneID:851551"
     mRNA            <432330..>433025
                     /gene="GRX6"
                     /locus_tag="YDL010W"
                     /product="glutathione-disulfide reductase GRX6"
                     /transcript_id="NM_001180069.1"
                     /db_xref="GI:296143346"
                     /db_xref="GeneID:851551"
     CDS             432330..433025
                     /gene="GRX6"
                     /locus_tag="YDL010W"
                     /note="Cis-golgi localized monothiol glutaredoxin, binds
                     Fe-S cluster; more similar in activity to dithiol than
                     other monothiol glutaredoxins; involved in the oxidative
                     stress response; GRX6 has a paralog, GRX7, that arose from
                     the whole genome duplication"
                     /codon_start=1
                     /product="glutathione-disulfide reductase GRX6"
                     /protein_id="NP_010274.1"
                     /db_xref="GI:6320193"
                     /db_xref="SGD:S000002168"
                     /db_xref="GeneID:851551"
                     /translation="MIPSNKRNARILSITTLLLLLVFFVAQNANFLTVEIKEETSKAF
                     STNMDNMAGGSSREYAAMPTSTTNKGSSEVDEEINEIKQKVGLQQPIASVDDSLSAIK
                     NDKGSRITKAFNVQKEYSLILDLSPIIIFSKSTCSYSKGMKELLENEYQFIPNYYIIE
                     LDKHGHGEELQEYIKLVTGRGTVPNLLVNGVSRGGNEEIKKLHTQGKLLESLQVWSDG
                     KFSVEQREKPSNN"
     gene            complement(<432925..>433248)
                     /locus_tag="YDL009C"
                     /db_xref="GeneID:851553"
     mRNA            complement(<432925..>433248)
                     /locus_tag="YDL009C"
                     /product="hypothetical protein"
                     /transcript_id="NM_001270742.1"
                     /db_xref="GI:398364862"
                     /db_xref="GeneID:851553"
     CDS             complement(432925..433248)
                     /locus_tag="YDL009C"
                     /note="hypothetical protein; mRNA identified as translated
                     by ribosome profiling data; partially overlaps the
                     verified ORF YDL010W; YDL009C is not an essential gene"
                     /codon_start=1
                     /product="hypothetical protein"
                     /protein_id="NP_001257671.1"
                     /db_xref="GI:398364863"
                     /db_xref="SGD:S000002167"
                     /db_xref="GeneID:851553"
                     /translation="MKALSVLCFHNPFKRCLGQKSFFVGDSFFIPTPKRLVLGKLRLS
                     NYTAFHDLIIHDLFIYIFILNFFFFPFCNNFNYWKVFHVAQPRIYHHSRLVMILKVSL
                     ECAVS"
     gene            <433497..>433994
                     /gene="APC11"
                     /locus_tag="YDL008W"
                     /db_xref="GeneID:851554"
     mRNA            <433497..>433994
                     /gene="APC11"
                     /locus_tag="YDL008W"
                     /product="anaphase promoting complex subunit 11"
                     /transcript_id="NM_001180067.3"
                     /db_xref="GI:398364868"
                     /db_xref="GeneID:851554"
     CDS             433497..433994
                     /gene="APC11"
                     /locus_tag="YDL008W"
                     /EC_number="6.3.2.-"
                     /note="Catalytic core subunit, Anaphase-Promoting
                     Complex/Cyclosome (APC/C); which is a ubiquitin-protein
                     ligase required for degradation of anaphase inhibitors,
                     including mitotic cyclins, during the metaphase/anaphase
                     transition; contains a RING-H2 domain that is required for
                     activity"
                     /codon_start=1
                     /product="anaphase promoting complex subunit 11"
                     /protein_id="NP_010276.3"
                     /db_xref="GI:398364869"
                     /db_xref="SGD:S000002166"
                     /db_xref="GeneID:851554"
                     /translation="MKVKINEVHSVFAWSWHIPSTSDEDAANNDPIGNDEDEDVCGIC
                     RASYNGTCPSCKFPGDQCPLVIGLCHHNFHDHCIYRWLDTPTSKGLCPMCRQTFQLQK
                     GLAINDAHVQKFVEIVSRRREEMIEEGVAEEFVDFDEPIRQNTDNPIGRQQVDTILDE
                     DFLLR"
     gene            complement(434264..434336)
                     /locus_tag="tT(AGU)D"
                     /db_xref="GeneID:851555"
     tRNA            complement(434264..434336)
                     /locus_tag="tT(AGU)D"
                     /product="tRNA-Thr"
                     /note="Threonine tRNA (tRNA-Thr), predicted by tRNAscan-SE
                     analysis"
                     /db_xref="SGD:S000006739"
                     /db_xref="GeneID:851555"
     LTR             complement(434423..434739)
                     /note="Ty1 LTR"
                     /db_xref="SGD:S000006842"
     rep_origin      434784..435989
                     /note="ARS415;
                     Putative replication origin; identified in multiple array
                     studies, not yet confirmed by plasmid-based assay"
                     /db_xref="SGD:S000130173"
     gene            complement(<436567..>436824)
                     /locus_tag="YDL007C-A"
                     /db_xref="GeneID:3799969"
     mRNA            complement(<436567..>436824)
                     /locus_tag="YDL007C-A"
                     /product="hypothetical protein"
                     /transcript_id="NM_001184682.1"
                     /db_xref="GI:296143348"
                     /db_xref="GeneID:3799969"
     CDS             complement(436567..436824)
                     /locus_tag="YDL007C-A"
                     /codon_start=1
                     /product="hypothetical protein"
                     /protein_id="NP_001032574.1"
                     /db_xref="GI:82795244"
                     /db_xref="SGD:S000113557"
                     /db_xref="GeneID:3799969"
                     /translation="MFLPIIFHTILTLLNFGKYYCLPIQEDDDKSGKEIEQILDNNIE
                     SLGLLLNSMSLSSNFTTGDPELDSLFQDDLIPELYSVLDGF"
     LTR             437149..437518
                     /note="Ty4 LTR"
                     /db_xref="SGD:S000006843"
     gene            437772..437853
                     /locus_tag="tS(AGA)D1"
                     /db_xref="GeneID:851556"
     tRNA            437772..437853
                     /locus_tag="tS(AGA)D1"
                     /product="tRNA-Ser"
                     /note="Serine tRNA (tRNA-Ser), predicted by tRNAscan-SE
                     analysis"
                     /db_xref="SGD:S000006721"
                     /db_xref="GeneID:851556"
     gene            <438047..>439360
                     /gene="RPT2"
                     /locus_tag="YDL007W"
                     /gene_synonym="YHS4; YTA5"
                     /db_xref="GeneID:851557"
     mRNA            <438047..>439360
                     /gene="RPT2"
                     /locus_tag="YDL007W"
                     /gene_synonym="YHS4; YTA5"
                     /product="proteasome regulatory particle base subunit
                     RPT2"
                     /transcript_id="NM_001180066.1"
                     /db_xref="GI:296143349"
                     /db_xref="GeneID:851557"
     CDS             438047..439360
                     /gene="RPT2"
                     /locus_tag="YDL007W"
                     /gene_synonym="YHS4; YTA5"
                     /note="ATPase of the 19S regulatory particle of the 26S
                     proteasome; one of six ATPases of the regulatory particle;
                     involved in the degradation of ubiquitinated substrates;
                     required for normal peptide hydrolysis by the core 20S
                     particle; N-myristoylation of Rpt2p at Gly2 is involved in
                     regulating the proper intracellular distribution of
                     proteasome activity by controlling the nuclear
                     localization of the 26S proteasome"
                     /codon_start=1
                     /product="proteasome regulatory particle base subunit
                     RPT2"
                     /protein_id="NP_010277.1"
                     /db_xref="GI:6320197"
                     /db_xref="SGD:S000002165"
                     /db_xref="GeneID:851557"
                     /translation="MGQGVSSGQDKKKKKGSNQKPKYEPPVQSKFGRKKRKGGPATAE
                     KLPNIYPSTRCKLKLLRMERIKDHLLLEEEFVSNSEILKPFEKKQEEEKKQLEEIRGN
                     PLSIGTLEEIIDDDHAIVTSPTMPDYYVSILSFVDKELLEPGCSVLLHHKTMSIVGVL
                     QDDADPMVSVMKMDKSPTESYSDIGGLESQIQEIKESVELPLTHPELYEEMGIKPPKG
                     VILYGAPGTGKTLLAKAVANQTSATFLRIVGSELIQKYLGDGPRLCRQIFKVAGENAP
                     SIVFIDEIDAIGTKRYDSNSGGEREIQRTMLELLNQLDGFDDRGDVKVIMATNKIETL
                     DPALIRPGRIDRKILFENPDLSTKKKILGIHTSKMNLSEDVNLETLVTTKDDLSGADI
                     QAMCTEAGLLALRERRMQVTAEDFKQAKERVMKNKVEENLEGLYL"
     gene            <439909..>440754
                     /gene="PTC1"
                     /locus_tag="YDL006W"
                     /gene_synonym="CWH47; KCS2; TPD1"
                     /db_xref="GeneID:851558"
     mRNA            <439909..>440754
                     /gene="PTC1"
                     /locus_tag="YDL006W"
                     /gene_synonym="CWH47; KCS2; TPD1"
                     /product="type 2C protein phosphatase PTC1"
                     /transcript_id="NM_001180065.3"
                     /db_xref="GI:398364892"
                     /db_xref="GeneID:851558"
     CDS             439909..440754
                     /gene="PTC1"
                     /locus_tag="YDL006W"
                     /gene_synonym="CWH47; KCS2; TPD1"
                     /EC_number="3.1.3.16"
                     /note="Type 2C protein phosphatase (PP2C);
                     dephosphorylates Hog1p, inactivating osmosensing MAPK
                     cascade; involved in Fus3p activation during pheromone
                     response; deletion affects precursor tRNA splicing,
                     mitochondrial inheritance, and sporulation"
                     /codon_start=1
                     /product="type 2C protein phosphatase PTC1"
                     /protein_id="NP_010278.3"
                     /db_xref="GI:398364893"
                     /db_xref="SGD:S000002164"
                     /db_xref="GeneID:851558"
                     /translation="MSNHSEILERPETPYDITYRVGVAENKNSKFRRTMEDVHTYVKN
                     FASRLDWGYFAVFDGHAGIQASKWCGKHLHTIIEQNILADETRDVRDVLNDSFLAIDE
                     EINTKLVGNSGCTAAVCVLRWELPDSVSDDSMDLAQHQRKLYTANVGDSRIVLFRNGN
                     SIRLTYDHKASDTLEMQRVEQAGGLIMKSRVNGMLAVTRSLGDKFFDSLVVGSPFTTS
                     VEITSEDKFLILACDGLWDVIDDQDACELIKDITEPNEAAKVLVRYALENGTTDNVTV
                     MVVFL"
     gene            complement(<441014..>442309)
                     /gene="MED2"
                     /locus_tag="YDL005C"
                     /db_xref="GeneID:851559"
     mRNA            complement(<441014..>442309)
                     /gene="MED2"
                     /locus_tag="YDL005C"
                     /product="Med2p"
                     /transcript_id="NM_001180064.3"
                     /db_xref="GI:398364900"
                     /db_xref="GeneID:851559"
     CDS             complement(441014..442309)
                     /gene="MED2"
                     /locus_tag="YDL005C"
                     /note="Subunit of the RNA polymerase II mediator complex;
                     associates with core polymerase subunits to form the RNA
                     polymerase II holoenzyme; essential for transcriptional
                     regulation; relocalizes to the cytosol in response to
                     hypoxia"
                     /codon_start=1
                     /product="Med2p"
                     /protein_id="NP_010279.3"
                     /db_xref="GI:398364901"
                     /db_xref="SGD:S000002163"
                     /db_xref="GeneID:851559"
                     /translation="MVVQNSPVSSVHTANFSERGSNTRTMTYKNKLTVCFDDILKVGA
                     EMMMQQQLKNVQLDSYLVNGFSQSQQKLLKEKVKLFHGILDDLETSLSQSSSYLETLT
                     ALGKEKEKEREEAEKKRAEQENMRKVREQEELKKRQELEEASQQQQLQQNSKEKNGLG
                     LNFSTTAPANTTDANGSKENYQELGSLQSSSQTQLENANAANNGAAFSPLTTTRIQSQ
                     QAQPSDVMFNDLNSMDISMFSGLDSTGFDSTAFNATVDETKGFDDNDSGNNYNDINIS
                     SIENNINNNINSTKNGKDNNNESNKNNNGDEKNKNNNEDNENNNNSSEKNNNNNNNNN
                     NNNDDNGNNNNNNSGNDNNNTTNNDSNNKNNSITTGNDNENIVNNDLPTTVVSNPGDN
                     PPPADNGEEYLTLNDFNDLNIDWSTTGDNGELDLSGFNI"
     gene            <443029..>443511
                     /gene="ATP16"
                     /locus_tag="YDL004W"
                     /db_xref="GeneID:851560"
     mRNA            <443029..>443511
                     /gene="ATP16"
                     /locus_tag="YDL004W"
                     /product="F1F0 ATP synthase subunit delta"
                     /transcript_id="NM_001180063.1"
                     /db_xref="GI:296143352"
                     /db_xref="GeneID:851560"
     CDS             443029..443511
                     /gene="ATP16"
                     /locus_tag="YDL004W"
                     /EC_number="3.6.3.14"
                     /note="Delta subunit of the central stalk of mitochondrial
                     F1F0 ATP synthase; F1F0 ATP synthase is a large,
                     evolutionarily conserved enzyme complex required for ATP
                     synthesis; F1 translationally regulates ATP6 and ATP8
                     expression to achieve a balanced output of ATP synthase
                     genes encoded in nucleus and mitochondria; phosphorylated"
                     /codon_start=1
                     /product="F1F0 ATP synthase subunit delta"
                     /protein_id="NP_010280.1"
                     /db_xref="GI:6320200"
                     /db_xref="SGD:S000002162"
                     /db_xref="GeneID:851560"
                     /translation="MLRSIIGKSASRSLNFVAKRSYAEAAAASSGLKLQFALPHETLY
                     SGSEVTQVNLPAKSGRIGVLANHVPTVEQLLPGVVEVMEGSNSKKFFISGGFATVQPD
                     SQLCVTAIEAFPLESFSQENIKNLLAEAKKNVSSSDAREAAEAAIQVEVLENLQSVLK
                     "
     gene            <444683..>446383
                     /gene="MCD1"
                     /locus_tag="YDL003W"
                     /gene_synonym="PDS3; RHC21; SCC1"
                     /db_xref="GeneID:851561"
     mRNA            <444683..>446383
                     /gene="MCD1"
                     /locus_tag="YDL003W"
                     /gene_synonym="PDS3; RHC21; SCC1"
                     /product="Mcd1p"
                     /transcript_id="NM_001180062.1"
                     /db_xref="GI:296143353"
                     /db_xref="GeneID:851561"
     CDS             444683..446383
                     /gene="MCD1"
                     /locus_tag="YDL003W"
                     /gene_synonym="PDS3; RHC21; SCC1"
                     /note="Essential alpha-kleisin subunit of the cohesin
                     complex; required for sister chromatid cohesion in mitosis
                     and meiosis; apoptosis induces cleavage and translocation
                     of a C-terminal fragment to mitochondria; expression peaks
                     in S phase"
                     /codon_start=1
                     /product="Mcd1p"
                     /protein_id="NP_010281.1"
                     /db_xref="GI:6320201"
                     /db_xref="SGD:S000002161"
                     /db_xref="GeneID:851561"
                     /translation="MVTENPQRLTVLRLATNKGPLAQIWLASNMSNIPRGSVIQTHIA
                     ESAKEIAKASGCDDESGDNEYITLRTSGELLQGIVRVYSKQATFLLTDIKDTLTKISM
                     LFKTSQKMTSTVNRLNTVTRVHQLMLEDAVTEREVLVTPGLEFLDDTTIPVGLMAQEN
                     SMERKVQGAAPWDTSLEVGRRFSPDEDFEHNNLSSMNLDFDIEEGPITSKSWEEGTRQ
                     SSRNFDTHENYIQDDDFPLDDAGTIGWDLGITEKNDQNNDDDDNSVEQGRRLGESIMS
                     EEPTDFGFDLDIEKEAPAGNIDTITDAMTESQPKQTGTRRNSKLLNTKSIQIDEETEN
                     SESIASSNTYKEERSNNLLTPQPTNFTTKRLWSEITESMSYLPDPILKNFLSYESLKK
                     RKIHNGREGSIEEPELNVSLNLTDDVISNAGTNDNSFNELTDNMSDFVPIDAGLNEAP
                     FPEENIIDAKTRNEQTTIQTEKVRPTPGEVASKAIVQMAKILRKELSEEKEVIFTDVL
                     KSQANTEPENITKREASRGFFDILSLATEGCIGLSQTEAFGNIKIDAKPALFERFINA
                     "
     gene            complement(<446967..>447578)
                     /gene="NHP10"
                     /locus_tag="YDL002C"
                     /gene_synonym="HMO2"
                     /db_xref="GeneID:851562"
     mRNA            complement(<446967..>447578)
                     /gene="NHP10"
                     /locus_tag="YDL002C"
                     /gene_synonym="HMO2"
                     /product="Nhp10p"
                     /transcript_id="NM_001180061.3"
                     /db_xref="GI:398364916"
                     /db_xref="GeneID:851562"
     CDS             complement(446967..447578)
                     /gene="NHP10"
                     /locus_tag="YDL002C"
                     /gene_synonym="HMO2"
                     /note="Non-essential INO80 chromatin remodeling complex
                     subunit; preferentially binds DNA ends, protecting them
                     from exonucleatic cleavage; deletion affects telomere
                     maintenance via recombination; related to mammalian high
                     mobility group proteins"
                     /codon_start=1
                     /product="Nhp10p"
                     /protein_id="NP_010282.3"
                     /db_xref="GI:398364917"
                     /db_xref="SGD:S000002160"
                     /db_xref="GeneID:851562"
                     /translation="MSVEEKKRRLEELKDQNVVLGLAIQRSRLSVKRLKLEYGVLLER
                     LESRIELDPELNCEDPLPTLASFKQELLTKPFRKSKTKRHKVKERDPNMPKRPTNAYL
                     LYCEMNKERIRQNGSLDVTRDLAEGWKNLNEQDRKPYYKLYSEDRERYQMEMEIYNKK
                     ISNIDADDDKEENEQKIKNNEEGSSTKVADSKGGEDGSLVSSN"
     gene            <447984..>449276
                     /gene="RMD1"
                     /locus_tag="YDL001W"
                     /db_xref="GeneID:851563"
     mRNA            <447984..>449276
                     /gene="RMD1"
                     /locus_tag="YDL001W"
                     /product="Rmd1p"
                     /transcript_id="NM_001180060.3"
                     /db_xref="GI:398364922"
                     /db_xref="GeneID:851563"
     CDS             447984..449276
                     /gene="RMD1"
                     /locus_tag="YDL001W"
                     /note="Cytoplasmic protein required for sporulation"
                     /codon_start=1
                     /product="Rmd1p"
                     /protein_id="NP_010283.3"
                     /db_xref="GI:398364923"
                     /db_xref="SGD:S000002159"
                     /db_xref="GeneID:851563"
                     /translation="MVDSNDDQPERHALLHNDIQTSNNSRPSLVQKKYLPTPQDTRKS
                     RASYTGSAMINPTSKQSRTGSGAQRTSRTAQKLKLLPEEPFQRDSERLTDLKNQEVYS
                     QVNRIKDKPARRDAEKLGKAHRHLLPRSTAYCTASSYNMKELVRWLKDCRKLHHTHPK
                     LFDECLYTPFIYNDWRGDKRFEDEDVIRLDDEGGEIIVSDKHPDLFIFEYGVVVMWGF
                     TEREEKAFLNDIEKFEKEKLAEEDIQVEEFNYYVTKSYQPRIYNDFITLRDGSNYMVK
                     LSISHAIAQSVKISLFEELVDNTIEDTQDIPQEIAYSGKVSMSKEDIMKSIGELFILR
                     ININLHGSVLDSPEIMWSEPQLEPIYQATRGYLEINQRVSLLNQRLEVISDLLQMLKE
                     QLGHSHEEYLEFIVILLVGVEVLISVINIVVDMLASQH"
     centromere      449711..449821
                     /note="CEN4; Chromosome IV centromere"
                     /db_xref="SGD:S000006466"
     centromere      449711..449720
                     /note="CEN4_CDEI of CEN4"
     centromere      449721..449796
                     /note="CEN4_CDEII of CEN4"
     centromere      449797..449821
                     /note="CEN4_CDEIII of CEN4"
     gene            complement(<450220..>452475)
                     /gene="NTH1"
                     /locus_tag="YDR001C"
                     /db_xref="GeneID:851564"
     mRNA            complement(<450220..>452475)
                     /gene="NTH1"
                     /locus_tag="YDR001C"
                     /product="alpha,alpha-trehalase NTH1"
                     /transcript_id="NM_001180309.1"
                     /db_xref="GI:296143356"
                     /db_xref="GeneID:851564"
     CDS             complement(450220..452475)
                     /gene="NTH1"
                     /locus_tag="YDR001C"
                     /EC_number="3.2.1.28"
                     /note="Neutral trehalase, degrades trehalose; required for
                     thermotolerance and may mediate resistance to other
                     cellular stresses; may be phosphorylated by Cdc28p;
                     inhibited by Dcs1p; NTH1 has a paralog, NTH2, that arose
                     from the whole genome duplication"
                     /codon_start=1
                     /product="alpha,alpha-trehalase NTH1"
                     /protein_id="NP_010284.1"
                     /db_xref="GI:6320204"
                     /db_xref="SGD:S000002408"
                     /db_xref="GeneID:851564"
                     /translation="MSQVNTSQGPVAQGRQRRLSSLSEFNDPFSNAEVYYGPPTDPRK
                     QKQAKPAKINRTRTMSVFDNVSPFKKTGFGKLQQTRRGSEDDTYSSSQGNRRFFIEDV
                     DKTLNELLAAEDTDKNYQITIEDTGPKVLKVGTANSYGYKHINIRGTYMLSNLLQELT
                     IAKSFGRHQIFLDEARINENPVNRLSRLINTQFWNSLTRRVDLNNVGEIAKDTKIDTP
                     GAKNPRIYVPYDCPEQYEFYVQASQMHPSLKLEVEYLPKKITAEYVKSVNDTPGLLAL
                     AMEEHFNPSTGEKTLIGYPYAVPGGRFNELYGWDSYMMALGLLEANKTDVARGMVEHF
                     IFEINHYGKILNANRSYYLCRSQPPFLTEMALVVFKKLGGRSNPDAVDLLKRAFQASI
                     KEYKTVWTASPRLDPETGLSRYHPNGLGIPPETESDHFDTVLLPYASKHGVTLDEFKQ
                     LYNDGKIKEPKLDEFFLHDRGVRESGHDTTYRFEGVCAYLATIDLNSLLYKYEIDIAD
                     FIKEFCDDKYEDPLDHSITTSAMWKEMAKIRQEKITKYMWDDESGFFFDYNTKIKHRT
                     SYESATTFWALWAGLATKEQAQKMVEKALPKLEMLGGLAACTERSRGPISISRPIRQW
                     DYPFGWAPHQILAWEGLRSYGYLTVTNRLAYRWLFMMTKAFVDYNGIVVEKYDVTRGT
                     DPHRVEAEYGNQGADFKGAATEGFGWVNASYILGLKYMNSHARRALGACIPPISFFSS
                     LRPQERNLYGL"
     gene            <453045..>453650
                     /gene="YRB1"
                     /locus_tag="YDR002W"
                     /gene_synonym="CST20; HTN1; SFO1; STP52"
                     /db_xref="GeneID:851565"
     mRNA            <453045..>453650
                     /gene="YRB1"
                     /locus_tag="YDR002W"
                     /gene_synonym="CST20; HTN1; SFO1; STP52"
                     /product="Yrb1p"
                     /transcript_id="NM_001180310.1"
                     /db_xref="GI:296143357"
                     /db_xref="GeneID:851565"
     CDS             453045..453650
                     /gene="YRB1"
                     /locus_tag="YDR002W"
                     /gene_synonym="CST20; HTN1; SFO1; STP52"
                     /note="Ran GTPase binding protein; involved in nuclear
                     protein import and RNA export, ubiquitin-mediated protein
                     degradation during the cell cycle; shuttles between the
                     nucleus and cytoplasm; is essential; homolog of human
                     RanBP1"
                     /codon_start=1
                     /product="Yrb1p"
                     /protein_id="NP_010285.1"
                     /db_xref="GI:6320205"
                     /db_xref="SGD:S000002409"
                     /db_xref="GeneID:851565"
                     /translation="MSSEDKKPVVDKKEEAAPKPPSSAVFSMFGGKKAEKPETKKDEE
                     DTKEETKKEGDDAPESPDIHFEPVVHLEKVDVKTMEEDEEVLYKVRAKLFRFDADAKE
                     WKERGTGDCKFLKNKKTNKVRILMRRDKTLKICANHIIAPEYTLKPNVGSDRSWVYAC
                     TADIAEGEAEAFTFAIRFGSKENADKFKEEFEKAQEINKKA"
     gene            <454122..>454754
                     /gene="RCR2"
                     /locus_tag="YDR003W"
                     /gene_synonym="SSH5"
                     /db_xref="GeneID:851566"
     mRNA            <454122..>454754
                     /gene="RCR2"
                     /locus_tag="YDR003W"
                     /gene_synonym="SSH5"
                     /product="Rcr2p"
                     /transcript_id="NM_001180311.3"
                     /db_xref="GI:398364940"
                     /db_xref="GeneID:851566"
     CDS             454122..454754
                     /gene="RCR2"
                     /locus_tag="YDR003W"
                     /gene_synonym="SSH5"
                     /note="Vacuolar protein; presumably functions within the
                     endosomal-vacuolar trafficking pathway, affecting events
                     that determine whether plasma membrane proteins are
                     degraded or routed to the plasma membrane; RCR2 has a
                     paralog, RCR1, that arose from the whole genome
                     duplication"
                     /codon_start=1
                     /product="Rcr2p"
                     /protein_id="NP_010286.3"
                     /db_xref="GI:398364941"
                     /db_xref="SGD:S000002410"
                     /db_xref="GeneID:851566"
                     /translation="MILREQIDFLIHKRQDDNNNNGEAITDDDPFSSSSWRWGRWIFF
                     IFFIVALLILLFSTAKVNRRRRIMGQAPIRGTAWLTPPTYRQSERDYNGTQRCVEDYV
                     PEYTETANENDLGFYDERGEFHPNGKTEYLAPPPLSEEQASSTDKDLQRPVAAVVRIP
                     SESEFDFNLLRPTMNNFVNGQSNRNEQHSPTVESSSFDVNNAPARAKVSK"
     gene            <454782..>454904
                     /locus_tag="YDR003W-A"
                     /db_xref="GeneID:1466432"
     mRNA            <454782..>454904
                     /locus_tag="YDR003W-A"
                     /product="hypothetical protein"
                     /transcript_id="NM_001184646.3"
                     /db_xref="GI:398364946"
                     /db_xref="GeneID:1466432"
     CDS             454782..454904
                     /locus_tag="YDR003W-A"
                     /note="hypothetical protein; identified by expression
                     profiling and mass spectrometry"
                     /codon_start=1
                     /product="hypothetical protein"
                     /protein_id="NP_878061.3"
                     /db_xref="GI:398364947"
                     /db_xref="SGD:S000028819"
                     /db_xref="GeneID:1466432"
                     /translation="MTCGIENSYKSAEKKKKYRSFRFFESRDYSELCIIVGTYY"
     gene            <455201..>456583
                     /gene="RAD57"
                     /locus_tag="YDR004W"
                     /db_xref="GeneID:851567"
     mRNA            <455201..>456583
                     /gene="RAD57"
                     /locus_tag="YDR004W"
                     /product="Rad57p"
                     /transcript_id="NM_001180312.1"
                     /db_xref="GI:296143360"
                     /db_xref="GeneID:851567"
     CDS             455201..456583
                     /gene="RAD57"
                     /locus_tag="YDR004W"
                     /note="Protein that stimulates strand exchange; stimulates
                     strand exchange by stabilizing the binding of Rad51p to
                     single-stranded DNA; involved in the recombinational
                     repair of double-strand breaks in DNA during vegetative
                     growth and meiosis; forms heterodimer with Rad55p"
                     /codon_start=1
                     /product="Rad57p"
                     /protein_id="NP_010287.1"
                     /db_xref="GI:6320207"
                     /db_xref="SGD:S000002411"
                     /db_xref="GeneID:851567"
                     /translation="MPRALSIKFDNTYMDLYDELPESKLLYDEEFSYLLDAVRQNGVC
                     VVDFLTLTPKELARLIQRSINEVFRFQQLLVHEYNEKYLEICEKNSISPDNGPECFTT
                     ADVAMDELLGGGIFTHGITEIFGESSTGKSQLLMQLALSVQLSEPAGGLGGKCVYITT
                     EGDLPTQRLESMLSSRPAYEKLGITQSNIFTVSCNDLINQEHIINVQLPILLERSKGS
                     IKLVIIDSISHHLRVELQNKSFRESQENKNYLDRMAEKLQILAHDYSLSVVVANQVGD
                     KPLANSPVAHRTYVTDYDYQLGWLVGWKNSTILYRQMNSLLGASSNNDEILSDDEDYM
                     LIERVMSTVNDRNYDFFSKKKPPIIENKTVERNSSSPISRQSKKRKFDYRVPNLGLTW
                     SNHVSTRILLQKSFKASTIIQRGEAHLYKGGDSASFWQVKRTMKVVYSTFAKPGQIAY
                     QITKRGIETA"
     gene            complement(<456836..>458103)
                     /gene="MAF1"
                     /locus_tag="YDR005C"
                     /db_xref="GeneID:851568"
     mRNA            complement(join(<456836..458017,458098..>458103))
                     /gene="MAF1"
                     /locus_tag="YDR005C"
                     /product="Maf1p"
                     /transcript_id="NM_001180313.1"
                     /db_xref="GI:296143361"
                     /db_xref="GeneID:851568"
     CDS             complement(join(456836..458017,458098..458103))
                     /gene="MAF1"
                     /locus_tag="YDR005C"
                     /note="Highly conserved negative regulator of RNA
                     polymerase III; involved in tRNA processing and stability;
                     inhibits tRNA degradation via rapid tRNA decay (RTD)
                     pathway; binds N-terminal domain of Rpc160p subunit of Pol
                     III to prevent closed-complex formation; localization and
                     activity are regulated by phosphorylation, mediated by
                     TORC1, protein kinase A, and Sch9p; localizes to cytoplasm
                     during vegetative growth and translocates to nucleus and
                     nucleolus under stress conditions"
                     /codon_start=1
                     /product="Maf1p"
                     /protein_id="NP_010288.1"
                     /db_xref="GI:6320208"
                     /db_xref="SGD:S000002412"
                     /db_xref="GeneID:851568"
                     /translation="MKFIDELDIERVNQTLNFETNDCKIVGSCDIFTTKAVASDRKLY
                     KTIDQHLDTILQENENYNATLQQQLAAPETNQSPCSSPFYSNRRDSNSFWEQKRRISF
                     SEYNSNNNTNNSNGNSSNNNNYSGPNGSSPATFPKSAKLNDQNLKELVSNYDSGSMSS
                     SSLDSSSKNDERIRRRSSSSISSFKSGKSSNNNYSSGTATNNVNKRRKSSINERPSNL
                     SLGPFGPINEPSSRKIFAYLIAILNASYPDHDFSSVEPTDFVKTSLKTFISKFENTLY
                     SLGRQPEEWVWEVINSHMTLSDCVLFQYSPSNSFLEDEPGYLWNLIGFLYNRKRKRVA
                     YLYLICSRLNSSTGEVEDALAKKPQGKLIIDDGSNEYEGEYDFTYDENVIDDKSDQEE
                     SLQ"
     gene            complement(<458542..>461247)
                     /gene="SOK1"
                     /locus_tag="YDR006C"
                     /db_xref="GeneID:851569"
     mRNA            complement(<458542..>461247)
                     /gene="SOK1"
                     /locus_tag="YDR006C"
                     /product="Sok1p"
                     /transcript_id="NM_001180314.3"
                     /db_xref="GI:398364966"
                     /db_xref="GeneID:851569"
     CDS             complement(458542..461247)
                     /gene="SOK1"
                     /locus_tag="YDR006C"
                     /note="hypothetical protein; overexpression suppresses the
                     growth defect of mutants lacking protein kinase A
                     activity; involved in cAMP-mediated signaling; localized
                     to the nucleus; similar to the mouse testis-specific
                     protein PBS13"
                     /codon_start=1
                     /product="Sok1p"
                     /protein_id="NP_010289.3"
                     /db_xref="GI:398364967"
                     /db_xref="SGD:S000002413"
                     /db_xref="GeneID:851569"
                     /translation="MDQPRTHSGPTTASNPAPSSTNSSSAPSATNSKQERSSSSLSKP
                     SSVVPSKDSPDGDAIAKTQAAALKNDMKSGDTSTLDGSSQNIIPNRASMQKYIDQSSD
                     LLSRSSGVITPSMSLNASTNATNNDSSGNSANSSDLKIPIDRDNTIFKTFDTKTGQFL
                     KNDDNEEEIRRNNKVDSIPPKNIYTNINNPSPSPPPSSKQPPSASAPQLPPATEPHKE
                     QAAQQQPPGNASNFLRIFSNKKMRSHSVPTILHSSLRKLSSHNQYYRNQNILLNHPTP
                     SGISKKKFSRNHHQPYLHSNNPLSSNPLSLKRAIFLNQQISGNASTNANNDNINNSTA
                     TSMTNQSFLSSSNFDLTLEDRINYIKATPTPVPFPPINLQGLKEIDLQEILKNPQLRH
                     DIIFDPLLQFRPNLDGERGNKKRQLANIYWNDVQNEIYVYSKRPEIFQYNRSRLVPLF
                     DTLRDVLLTIVPQKESPMINNVLDTELNIQELLKGSLIMSNLSGWLADLFKHHCAPMR
                     DPWVDKMSNKFKEAERDSSLTRLIEGLRLVFQILETMKLDIANHQIRILRPALLSNAV
                     EFEKQYFNTLIASKRVNLNTSLLWFDKKFNENVTAGLVRNPSSITIPDVYNICIRSII
                     NLLSCRKMVREYPTPLSFDHARLILLRADIRQIVCILVCRLLFQQLVANDPSMDKATK
                     EYVIHTYSTKRLKNEIISIITDEHGNCRWTKNTMSIAVHLCKVIDDLHREYDNNGSCE
                     QARRPQLPSLDNSKITFAKSWLSKQTQPLSEVYGVLENRVFKSLEDAIFNRSECTIDG
                     RVKQDFVYLYNTNNGNVGSTNTLSTTTDTASVKISPSLMSPSKTSTTTPTGNAIASRG
                     LFAATELEEFENVYRHLYALINLHWSVFGPHYIEMLGDKVNKKGI"
     STS             461739..461835
                     /standard_name="D17S1252"
                     /db_xref="UniSTS:149865"
     gene            <461842..>462516
                     /gene="TRP1"
                     /locus_tag="YDR007W"
                     /db_xref="GeneID:851570"
     mRNA            <461842..>462516
                     /gene="TRP1"
                     /locus_tag="YDR007W"
                     /product="phosphoribosylanthranilate isomerase TRP1"
                     /transcript_id="NM_001180315.3"
                     /db_xref="GI:398364970"
                     /db_xref="GeneID:851570"
     CDS             461842..462516
                     /gene="TRP1"
                     /locus_tag="YDR007W"
                     /EC_number="5.3.1.24"
                     /note="Phosphoribosylanthranilate isomerase; catalyzes the
                     third step in tryptophan biosynthesis; in 2004, the
                     sequence of TRP1 from strain S228C was updated by changing
                     the previously annotated internal STOP (TAA) to serine
                     (TCA)"
                     /codon_start=1
                     /product="phosphoribosylanthranilate isomerase TRP1"
                     /protein_id="NP_010290.3"
                     /db_xref="GI:398364971"
                     /db_xref="SGD:S000002414"
                     /db_xref="GeneID:851570"
                     /translation="MSVINFTGSSGPLVKVCGLQSTEAAECALDSDADLLGIICVPNR
                     KRTIDPVIARKISSLVKAYKNSSGTPKYLVGVFRNQPKEDVLALVNDYGIDIVQLHGD
                     ESWQEYQEFLGLPVIKRLVFPKDCNILLSAASQKPHSFIPLFDSEAGGTGELLDWNSI
                     SDWVGRQESPESLHFMLAGGLTPENVGDALRLNGVIGVDVSGGVETNGVKDSNKIANF
                     VKNAKK"
     rep_origin      462354..463192
                     /note="ARS1;
                     Early-firing autonomously replicating sequence; highly
                     efficient chromosomal replicator active in nearly every
                     cell cycle"
                     /db_xref="SGD:S000029652"
     gene            <463434..>464996
                     /gene="GAL3"
                     /locus_tag="YDR009W"
                     /db_xref="GeneID:851572"
     mRNA            <463434..>464996
                     /gene="GAL3"
                     /locus_tag="YDR009W"
                     /product="transcriptional regulator GAL3"
                     /transcript_id="NM_001180317.1"
                     /db_xref="GI:296143364"
                     /db_xref="GeneID:851572"
     CDS             463434..464996
                     /gene="GAL3"
                     /locus_tag="YDR009W"
                     /note="Transcriptional regulator; involved in activation
                     of the GAL genes in response to galactose; forms a complex
                     with Gal80p to relieve Gal80p inhibition of Gal4p; binds
                     galactose and ATP but does not have galactokinase
                     activity; GAL3 has a paralog, GAL1, that arose from the
                     whole genome duplication"
                     /codon_start=1
                     /product="transcriptional regulator GAL3"
                     /protein_id="NP_010292.1"
                     /db_xref="GI:6320212"
                     /db_xref="SGD:S000002416"
                     /db_xref="GeneID:851572"
                     /translation="MNTNVPIFSSPVRDLPRSFEQKHLAVVDAFFQTYHVKPDFIARS
                     PGRVNLIGEHIDYCDFSVLPLAIDVDMLCAVKILDEKNPSITLTNADPKFAQRKFDLP
                     LDGSYMAIDPSVSEWSNYFKCGLHVAHSYLKKIAPERFNNTPLVGAQIFCQSDIPTGG
                     GLSSAFTCAAALATIRANMGKNFDISKKDLTRITAVAEHYVGVNNGGMDQATSVYGEE
                     DHALYVEFRPKLKATPFKFPQLKNHEISFVIANTLVKSNKFETAPTNYNLRVIEVTVA
                     ANALATRYSVALPSHKDNSNSERGNLRDFMDAYYARYENQAQPWNGDIGTGIERLLKM
                     LQLVEESFSRKKSGFTVHEASTALNCSREEFTRDYLTTFPVRFQVLKLYQRAKHVYSE
                     SLRVLKALKMMTSATFHTDEDFFTDFGRLMNESQASCDKLYECSCIETNQICSIALAN
                     GSFGSRLTGAGWGGCTIHLVPSGANGNVEQVRKALIEKFYNVRYPDLTDEELKDAIIV
                     SKPALGTCLYEQ"
     gene            <465919..>470424
                     /gene="SNQ2"
                     /locus_tag="YDR011W"
                     /db_xref="GeneID:851574"
     mRNA            <465919..>470424
                     /gene="SNQ2"
                     /locus_tag="YDR011W"
                     /product="ATP-binding cassette transporter SNQ2"
                     /transcript_id="NM_001180319.1"
                     /db_xref="GI:296143365"
                     /db_xref="GeneID:851574"
     CDS             465919..470424
                     /gene="SNQ2"
                     /locus_tag="YDR011W"
                     /note="Plasma membrane ATP-binding cassette (ABC)
                     transporter; multidrug transporter involved in multidrug
                     resistance and resistance to singlet oxygen species"
                     /codon_start=1
                     /product="ATP-binding cassette transporter SNQ2"
                     /protein_id="NP_010294.1"
                     /db_xref="GI:6320214"
                     /db_xref="SGD:S000002418"
                     /db_xref="GeneID:851574"
                     /translation="MSNIKSTQDSSHNAVARSSSASFAASEESFTGITHDKDEQSDTP
                     ADKLTKMLTGPARDTASQISATVSEMAPDVVSKVESFADALSRHTTRSGAFNMDSDSD
                     DGFDAHAIFESFVRDADEQGIHIRKAGVTIEDVSAKGVDASALEGATFGNILCLPLTI
                     FKGIKAKRHQKMRQIISNVNALAEAGEMILVLGRPGAGCSSFLKVTAGEIDQFAGGVS
                     GEVAYDGIPQEEMMKRYKADVIYNGELDVHFPYLTVKQTLDFAIACKTPALRVNNVSK
                     KEYIASRRDLYATIFGLRHTYNTKVGNDFVRGVSGGERKRVSIAEALAAKGSIYCWDN
                     ATRGLDASTALEYAKAIRIMTNLLKSTAFVTIYQASENIYETFDKVTVLYSGKQIYFG
                     LIHEAKPYFAKMGYLCPPRQATAEFLTALTDPNGFHLIKPGYENKVPRTAEEFETYWL
                     NSPEFAQMKKDIAAYKEKVNTEKTKEVYDESMAQEKSKYTRKKSYYTVSYWEQVKLCT
                     QRGFQRIYGNKSYTVINVCSAIIQSFITGSLFYNTPSSTSGAFSRGGVLYFALLYYSL
                     MGLANISFEHRPILQKHKGYSLYHPSAEAIGSTLASFPFRMIGLTCFFIILFFLSGLH
                     RTAGSFFTIYLFLTMCSEAINGLFEMVSSVCDTLSQANSISGILMMSISMYSTYMIQL
                     PSMHPWFKWISYVLPIRYAFESMLNAEFHGRHMDCANTLVPSGGDYDNLSDDYKVCAF
                     VGSKPGQSYVLGDDYLKNQFQYVYKHTWRNFGILWCFLLGYVVLKVIFTEYKRPVKGG
                     GDALIFKKGSKRFIAHADEESPDNVNDIDAKEQFSSESSGANDEVFDDLEAKGVFIWK
                     DVCFTIPYEGGKRMLLDNVSGYCIPGTMTALMGESGAGKTTLLNTLAQRNVGIITGDM
                     LVNGRPIDASFERRTGYVQQQDIHIAELTVRESLQFSARMRRPQHLPDSEKMDYVEKI
                     IRVLGMEEYAEALVGEVGCGLNVEQRKKLSIGVELVAKPDLLLFLDEPTSGLDSQSSW
                     AIIQLLRKLSKAGQSILCTIHQPSATLFEEFDRLLLLRKGGQTVYFGDIGKNSATILN
                     YFERNGARKCDSSENPAEYILEAIGAGATASVKEDWHEKWLNSVEFEQTKEKVQDLIN
                     DLSKQETKSEVGDKPSKYATSYAYQFRYVLIRTSTSFWRSLNYIMSKMMLMLVGGLYI
                     GFTFFNVGKSYVGLQNAMFAAFISIILSAPAMNQIQGRAIASRELFEVRESQSNMFHW
                     SLVLITQYLSELPYHLFFSTIFFVSSYFPLRIFFEASRSAVYFLNYCIMFQLYYVGLG
                     LMILYMSPNLPSANVILGLCLSFMLSFCGVTQPVSLMPGFWTFMWKASPYTYFVQNLV
                     GIMLHKKPVVCKKKELNYFNPPNGSTCGEYMKPFLEKATGYIENPDATSDCAYCIYEV
                     GDNYLTHISSKYSYLWRNFGIFWIYIFFNIIAMVCVYYLFHVRQSSFLSPVSILNKIK
                     NIRKKKQ"
     gene            <471853..>472941
                     /gene="RPL4B"
                     /locus_tag="YDR012W"
                     /db_xref="GeneID:851575"
     mRNA            <471853..>472941
                     /gene="RPL4B"
                     /locus_tag="YDR012W"
                     /product="ribosomal 60S subunit protein L4B"
                     /transcript_id="NM_001180320.3"
                     /db_xref="GI:398364990"
                     /db_xref="GeneID:851575"
     CDS             471853..472941
                     /gene="RPL4B"
                     /locus_tag="YDR012W"
                     /note="Ribosomal 60S subunit protein L4B; homologous to
                     mammalian ribosomal protein L4 and bacterial L4; RPL4B has
                     a paralog, RPL4A, that arose from the whole genome
                     duplication"
                     /codon_start=1
                     /product="ribosomal 60S subunit protein L4B"
                     /protein_id="NP_010295.3"
                     /db_xref="GI:398364991"
                     /db_xref="SGD:S000002419"
                     /db_xref="GeneID:851575"
                     /translation="MSRPQVTVHSLTGEATANALPLPAVFSAPIRPDIVHTVFTSVNK
                     NKRQAYAVSEKAGHQTSAESWGTGRAVARIPRVGGGGTGRSGQGAFGNMCRGGRMFAP
                     TKTWRKWNVKVNHNEKRYATASAIAATAVASLVLARGHRVEKIPEIPLVVSTDLESIQ
                     KTKEAVAALKAVGAHSDLLKVLKSKKLRAGKGKYRNRRWTQRRGPLVVYAEDNGIVKA
                     LRNVPGVETANVASLNLLQLAPGAHLGRFVIWTEAAFTKLDQVWGSETVASSKVGYTL
                     PSHIISTSDVTRIINSSEIQSAIRPAGQATQKRTHVLKKNPLKNKQVLLRLNPYAKVF
                     AAEKLGSKKAEKTGTKPAAVFAETLKHD"
     gene            <473157..>473783
                     /gene="PSF1"
                     /locus_tag="YDR013W"
                     /gene_synonym="CDC101"
                     /db_xref="GeneID:851576"
     mRNA            <473157..>473783
                     /gene="PSF1"
                     /locus_tag="YDR013W"
                     /gene_synonym="CDC101"
                     /product="Psf1p"
                     /transcript_id="NM_001180321.3"
                     /db_xref="GI:398365002"
                     /db_xref="GeneID:851576"
     CDS             473157..473783
                     /gene="PSF1"
                     /locus_tag="YDR013W"
                     /gene_synonym="CDC101"
                     /note="Subunit of the GINS complex (Sld5p, Psf1p, Psf2p,
                     Psf3p); complex is localized to DNA replication origins
                     and implicated in assembly of the DNA replication
                     machinery"
                     /codon_start=1
                     /product="Psf1p"
                     /protein_id="NP_010296.3"
                     /db_xref="GI:398365003"
                     /db_xref="SGD:S000002420"
                     /db_xref="GeneID:851576"
                     /translation="MYGDLGNKLVLEAKRTKQLYARSNQDVNLPMYHEDIIRNILKEV
                     SNLRKNTEYLKEQQQLGMLDDKVAKCQYFVTLLCMERNKRCLLAYQRLRTDILDSMAW
                     NNNGLDLMSSITFSQQDTNNLSHQEQEYLKEYCDLITDLKSGDLVDIDLSGSLVPPSD
                     VFIDVRVLKDAGEIQTEYGVFNLIKDSQFFVRQSDVERLIQQGYLQKI"
     gene            <474046..>475989
                     /gene="RAD61"
                     /locus_tag="YDR014W"
                     /gene_synonym="WPL1"
                     /db_xref="GeneID:851577"
     mRNA            <474046..>475989
                     /gene="RAD61"
                     /locus_tag="YDR014W"
                     /gene_synonym="WPL1"
                     /product="Rad61p"
                     /transcript_id="NM_001180322.1"
                     /db_xref="GI:296143368"
                     /db_xref="GeneID:851577"
     CDS             474046..475989
                     /gene="RAD61"
                     /locus_tag="YDR014W"
                     /gene_synonym="WPL1"
                     /note="Subunit of a complex that inhibits sister chromatid
                     cohesion; also negatively regulates chromosome
                     condensation; inhibited by Eco1p-acetylated cohesin
                     subunits Smc3p and Mcd1p; binds Smc3p ATPase head of
                     cohesin; related to the human Wapl protein that controls
                     the association of cohesin with chromatin"
                     /codon_start=1
                     /product="Rad61p"
                     /protein_id="NP_010297.1"
                     /db_xref="GI:6320217"
                     /db_xref="SGD:S000002421"
                     /db_xref="GeneID:851577"
                     /translation="MRAYGKRGPVLRTPFRSNKGLPSSSDVEFSDDDVNSVIPDVSST
                     ISSSIADHPIEGLLDEPRKAQDSSSSFDGANEKPSSQLDSKRNDQNVKIITSSDTSMA
                     FMKDEKLSAFNFLDGSKASKRKRRRTYQKHDANITSSIEPDVQDEDSITMHNEFESIR
                     KIYNDINEFILKLPRADDDILNKMLENEMKMDDSIENNSIRTSKDKKYGKFRTILINK
                     NKENEIMGEEVDQKANTLSLNNADNSNAEKEGLTSTNHYNELKNMGDTIKYQDDIEFL
                     LSNSKSNDNTTVPINEYFKKLLNLSLMIINDEEFFQYAKRYFKKEIIKLSFAQFRSDF
                     PELILLQGYLLHKVSESQSDFPPSFDNFSIELSKDDGKIRTKKNKHIKKLSHLNFEDF
                     LRKTQFKTGLYYSLSLWEMHGNLSLDIIKRISILASNKDLFSRHVKTFIPLLEKLITA
                     SEFCHMYIEQPEMFDSLISNLNNQFKDMLDDDSLIKILILLTNMEVHNYTLWKEADMI
                     FQSSMNTILESIHPLTDAKVDNILLHLGLCLNICSRENSRLKLDGKLWYDMKTIFVKM
                     IRDGSDTENRLVQGLFYLNFSFLIKQRKENSNLDPGELNLLLVELEAFKSETSQFNEG
                     ISNKIEIALNYLKSIYTSERITI"
     gene            <477797..>478285
                     /gene="HED1"
                     /locus_tag="YDR014W-A"
                     /db_xref="GeneID:4036073"
     mRNA            <477797..>478285
                     /gene="HED1"
                     /locus_tag="YDR014W-A"
                     /product="Hed1p"
                     /transcript_id="NM_001184688.1"
                     /db_xref="GI:296143369"
                     /db_xref="GeneID:4036073"
     CDS             477797..478285
                     /gene="HED1"
                     /locus_tag="YDR014W-A"
                     /note="Meiosis-specific protein; down-regulates
                     Rad51p-mediated mitotic recombination when the meiotic
                     recombination machinery is impaired; prevents the
                     recruitment of Rad54p to site-specific DNA double-strand
                     breaks in vivo; early meiotic gene, transcribed
                     specifically during meiotic prophase"
                     /codon_start=1
                     /product="Hed1p"
                     /protein_id="NP_001035220.1"
                     /db_xref="GI:93117372"
                     /db_xref="SGD:S000113613"
                     /db_xref="GeneID:4036073"
                     /translation="MQQRSNRRSCSYIPLGVHNNAEKSLCTEVAPARKNKRSITTSPI
                     VNINVVERRLFNLELEKQQLRAKNLSENTGGGSPNGGAYLDAKKGVREQDQYQGGPSK
                     ELDRLQPPPSMKKSPPRKKKSLKDLIYETNKTFYQVDSNKVKYKVGLSKKQLLPSKTV
                     DN"
     gene            complement(<478474..>478758)
                     /gene="DAD1"
                     /locus_tag="YDR016C"
                     /db_xref="GeneID:851579"
     mRNA            complement(<478474..>478758)
                     /gene="DAD1"
                     /locus_tag="YDR016C"
                     /product="Dad1p"
                     /transcript_id="NM_001180324.3"
                     /db_xref="GI:398365022"
                     /db_xref="GeneID:851579"
     CDS             complement(478474..478758)
                     /gene="DAD1"
                     /locus_tag="YDR016C"
                     /note="Essential subunit of the Dam1 complex (aka DASH
                     complex); complex couples kinetochores to the force
                     produced by MT depolymerization thereby aiding in
                     chromosome segregation; is transferred to the kinetochore
                     prior to mitosis"
                     /codon_start=1
                     /product="Dad1p"
                     /protein_id="NP_010299.3"
                     /db_xref="GI:398365023"
                     /db_xref="SGD:S000002423"
                     /db_xref="GeneID:851579"
                     /translation="MMASTSNDEEKLISTTDKYFIEQRNIVLQEINETMNSILNGLNG
                     LNISLESSIAVGREFQSVSDLWKTLYDGLESLSDEAPIDEQPTLSQSKTK"
     gene            complement(<479115..>482267)
                     /gene="KCS1"
                     /locus_tag="YDR017C"
                     /db_xref="GeneID:851580"
     mRNA            complement(<479115..>482267)
                     /gene="KCS1"
                     /locus_tag="YDR017C"
                     /product="inositol polyphosphate kinase KCS1"
                     /transcript_id="NM_001180325.3"
                     /db_xref="GI:398365024"
                     /db_xref="GeneID:851580"
     CDS             complement(479115..482267)
                     /gene="KCS1"
                     /locus_tag="YDR017C"
                     /EC_number="2.7.4.21"
                     /note="Inositol hexakisphosphate and inositol
                     heptakisphosphate kinase; generation of high energy
                     inositol pyrophosphates by Kcs1p is required for many
                     processes such as vacuolar biogenesis, stress response,
                     and telomere maintenance; inositol hexakisphosphate is
                     also known as IP6; inositol heptakisphosphate is also
                     known as IP7"
                     /codon_start=1
                     /product="inositol polyphosphate kinase KCS1"
                     /protein_id="NP_010300.3"
                     /db_xref="GI:398365025"
                     /db_xref="SGD:S000002424"
                     /db_xref="GeneID:851580"
                     /translation="MDTSHEIHDKIPDTLREQQQHLRQKESEGCITTLKDLNVPETKK
                     LSSVLHGRKASTYLRIFRDDECLADNNNGVDSNNGGSVTCADKITRSEATPKSVPEGL
                     QVSEKKNNPDTLSSSLSSFILSNHEEPAIKPNKHVAHRNNITETGQGSGEDIAKQQSH
                     QPQVLHHQTSLKPIQNVDEGCISPKSTYQESLHGISEDLTLKPVSSATYYPHKSKADS
                     GYEEKDKMENDIDTIQPATINCASGIATLPSSYNRHTFKVKTYSTLSQSLRQENVNNR
                     SNEKKPQQFVPHSESIKEKPNTFEQDKEGEQADEEEDEGDNEHREYPLAVELKPFTNR
                     VGGHTAIFRFSKRAVCKALVNRENRWYENIELCHKELLQFMPRYIGVLNVRQHFQSKD
                     DFLSDLDQENNGKNDTSNENKDIEVNHNNNDDIALNTEPTGTPLTHIHSFPLEHSSRQ
                     VLEKEHPEIESVHPHVKRSLSSSNQPSLLPEVVLNDNRHIIPESLWYKYSDSPNSAPN
                     DSYFSSSSSHNSCSFGERGNTNKLKRRDSGSTMINTELKNLVIREVFAPKCFRRKRNS
                     NTTTMGNHNARLGSSPSFLTQKSRASSHDASNTSMKTLGDSSSQASLQMDDSKVNPNL
                     QDPFLKKSLHEKISNALDGSHSVMDLKQFHKNEQIKHKNSFCNSLSPILTATNSRDDG
                     EFATSPNYISNAQDGVFDMDEDTGNETINMDNHGCHLDSGKNMIIKSLAYNVSNDYSH
                     HDIESITFEETSHTIVSKFILLEDLTRNMNKPCALDLKMGTRQYGVDAKRAKQLSQRA
                     KCLKTTSRRLGVRICGLKVWNKDYYITRDKYFGRRVKVGWQFARVLARFLYDGKTIES
                     LIRQIPRLIKQLDTLYSEIFNLKGYRLYGASLLLMYDGDANKSNSKRKKAANVKVNLI
                     DFARCVTKEDAMECMDKFRIPPKSPNIEDKGFLRGVKSLRFYLLLIWNYLTSDMPLIF
                     DEVEMNDMISEEADSNSFTSATGSKINFNSKWDWLDEFDKEDEEMYNDPNSKLRQKWR
                     KYELIFDAEPRYNDDAQVSD"
     gene            complement(<482670..>483860)
                     /locus_tag="YDR018C"
                     /db_xref="GeneID:851581"
     mRNA            complement(<482670..>483860)
                     /locus_tag="YDR018C"
                     /product="putative acyltransferase"
                     /transcript_id="NM_001180326.1"
                     /db_xref="GI:296143372"
                     /db_xref="GeneID:851581"
     CDS             complement(482670..483860)
                     /locus_tag="YDR018C"
                     /EC_number="2.3.-.-"
                     /note="Probable membrane protein with three predicted
                     transmembrane domains; similar to C. elegans F55A11.5 and
                     maize 1-acyl-glycerol-3-phosphate acyltransferase; YDR018C
                     has a paralog, CST26, that arose from the whole genome
                     duplication"
                     /codon_start=1
                     /product="putative acyltransferase"
                     /protein_id="NP_010301.1"
                     /db_xref="GI:6320221"
                     /db_xref="SGD:S000002425"
                     /db_xref="GeneID:851581"
                     /translation="MKHSQKYRRYGIYEKTGNPFIKGLQRLLIACLFISGSLSIVVFQ
                     ICLQVLLPWSKIRFQNGINQSKKAFIVLLCMILNMVAPSSLNVTFETSRPLKNSSNAK
                     PCFRFKDRAIIIANHQMYADWIYLWWLSFVSNLGGNVYIILKKALQYIPLLGFGMRNF
                     KFIFLSRNWQKDEKALTNSLVSMDLNARCKGPLTNYKSCYSKTNESIAAYNLIMFPEG
                     TNLSLKTREKSEAFCQRAHLDHVQLRHLLLPHSKGLKFAVEKLAPSLDAIYDVTIGYS
                     PALRTEYVGTKFTLKKIFLMGVYPEKVDFYIREFRVNEIPLQDDEVFFNWLLGVWKEK
                     DQLLEDYYNTGQFKSNAKNDNQSIVVTTQTTGFQHETLTPRILSYYGFFAFLILVFVM
                     KKNH"
     rep_origin      483852..484096
                     /note="ARS417;
                     Autonomously Replicating Sequence"
                     /db_xref="SGD:S000118434"
     gene            complement(<484163..>485365)
                     /gene="GCV1"
                     /locus_tag="YDR019C"
                     /gene_synonym="GSD1"
                     /db_xref="GeneID:851582"
     mRNA            complement(<484163..>485365)
                     /gene="GCV1"
                     /locus_tag="YDR019C"
                     /gene_synonym="GSD1"
                     /product="glycine decarboxylase subunit T"
                     /transcript_id="NM_001180327.1"
                     /db_xref="GI:296143373"
                     /db_xref="GeneID:851582"
     CDS             complement(484163..485365)
                     /gene="GCV1"
                     /locus_tag="YDR019C"
                     /gene_synonym="GSD1"
                     /EC_number="2.1.2.10"
                     /note="T subunit of the mitochondrial glycine
                     decarboxylase complex; glycine decarboxylase is required
                     for the catabolism of glycine to 5,10-methylene-THF;
                     expression is regulated by levels of levels of
                     5,10-methylene-THF in the cytoplasm"
                     /codon_start=1
                     /product="glycine decarboxylase subunit T"
                     /protein_id="NP_010302.1"
                     /db_xref="GI:6320222"
                     /db_xref="SGD:S000002426"
                     /db_xref="GeneID:851582"
                     /translation="MSIIKKIVFKRFNSTLKKTALHDLHVSLGGTMVPYAGYSMPVLY
                     KGQTHIESHNWTRTNAGLFDVSHMLQSKLSGPHSVKFLQRVTPTDFNALPVGSGTLSV
                     LLNPQGGVVDDTIITKENDDNEFYIVTNAGCAERDTEFFHDELQNGSTLDCQWKIIEG
                     RSLLALQGPKAKDVLEPLLSKTAPGKDLKELFFGQRHEFALKDGSLVQIARGGYTGED
                     GFEISIANEKAVEFAEQLLANPVMKPIGLAARDSLRLEAGMCLYGHELDESITPVEAA
                     LNWVISKSRRDLVDQKYWFNGYAKIMDQLNNKTYSKVRVGFKYLKKGPAARNGVKIFL
                     PDAETEVGLVTSGSASPTLNNINIGQAYVQKGYHKKGTKLLVQVRNKFYPIELAKMPL
                     VPTHYYKQ"
     gene            complement(<485746..>486444)
                     /gene="DAS2"
                     /locus_tag="YDR020C"
                     /gene_synonym="RRT3"
                     /db_xref="GeneID:851583"
     mRNA            complement(<485746..>486444)
                     /gene="DAS2"
                     /locus_tag="YDR020C"
                     /gene_synonym="RRT3"
                     /product="putative uridine kinase DAS2"
                     /transcript_id="NM_001180328.3"
                     /db_xref="GI:398365046"
                     /db_xref="GeneID:851583"
     CDS             complement(485746..486444)
                     /gene="DAS2"
                     /locus_tag="YDR020C"
                     /gene_synonym="RRT3"
                     /EC_number="2.7.1.48"
                     /note="hypothetical protein; non-essential gene identified
                     in a screen for mutants with increased levels of rDNA
                     transcription; weak similarity with uridine kinases and
                     with phosphoribokinases"
                     /codon_start=1
                     /product="putative uridine kinase DAS2"
                     /protein_id="NP_010303.3"
                     /db_xref="GI:398365047"
                     /db_xref="SGD:S000002427"
                     /db_xref="GeneID:851583"
                     /translation="MDRKAVEEKRIVISIGGGHATGVGAIALDLQNTFKSLYNSINIR
                     VINLDNMIEGNIKSYNNNDYDFDNILNLVYEKHAVTSQNDMIQHDYEDPIDLIIVCGC
                     YALYDKRINEISQLKVFLDSDADKRLISLIKKKNVGSNEQLAQLITEYMDHLRPEMQQ
                     YIEPTRTFADLIIPSTNENLGRAVLVDGIVKAIEDTKSQIEGNNTNNKIRPRLWDFEA
                     ETMDLEKDRYYDLS"
     gene            <486804..>488003
                     /gene="FAL1"
                     /locus_tag="YDR021W"
                     /db_xref="GeneID:851584"
     mRNA            <486804..>488003
                     /gene="FAL1"
                     /locus_tag="YDR021W"
                     /product="ATP-dependent RNA helicase FAL1"
                     /transcript_id="NM_001180329.3"
                     /db_xref="GI:398365052"
                     /db_xref="GeneID:851584"
     CDS             486804..488003
                     /gene="FAL1"
                     /locus_tag="YDR021W"
                     /EC_number="3.6.4.13"
                     /note="Nucleolar protein required for maturation of 18S
                     rRNA; member of the eIF4A subfamily of DEAD-box
                     ATP-dependent RNA helicases"
                     /codon_start=1
                     /product="ATP-dependent RNA helicase FAL1"
                     /protein_id="NP_010304.3"
                     /db_xref="GI:398365053"
                     /db_xref="SGD:S000002428"
                     /db_xref="GeneID:851584"
                     /translation="MSFDREEDQKLKFKTSKKLKVSSTFESMNLKDDLLRGIYSYGFE
                     APSSIQSRAITQIISGKDVIAQAQSGTGKTATFTIGLLQAIDLRKKDLQALILSPTRE
                     LASQIGQVVKNLGDYMNVNAFAITGGKTLKDDLKKMQKHGCQAVSGTPGRVLDMIKKQ
                     MLQTRNVQMLVLDEADELLSETLGFKQQIYDIFAKLPKNCQVVVVSATMNKDILEVTR
                     KFMNDPVKILVKRDEISLEGIKQYVVNVDKEEWKFDTLCDIYDSLTITQCVIFCNTKK
                     KVDWLSQRLIQSNFAVVSMHGDMKQEERDKVMNDFRTGHSRVLISTDVWARGIDVQQV
                     SLVINYDLPEIIENYIHRIGRSGRFGRKGVAINFITKADLAKLREIEKFYSIKINPMP
                     ANFAELS"
     gene            complement(<488072..>488662)
                     /gene="ATG31"
                     /locus_tag="YDR022C"
                     /gene_synonym="CIS1"
                     /db_xref="GeneID:851585"
     mRNA            complement(<488072..>488662)
                     /gene="ATG31"
                     /locus_tag="YDR022C"
                     /gene_synonym="CIS1"
                     /product="Atg31p"
                     /transcript_id="NM_001180330.1"
                     /db_xref="GI:296143376"
                     /db_xref="GeneID:851585"
     CDS             complement(488072..488662)
                     /gene="ATG31"
                     /locus_tag="YDR022C"
                     /gene_synonym="CIS1"
                     /note="Autophagy-specific protein required for
                     autophagosome formation; may form a complex with Atg17p
                     and Atg29p that localizes other proteins to the
                     pre-autophagosomal structure; high-copy suppressor of CIK1
                     deletion"
                     /codon_start=1
                     /product="Atg31p"
                     /protein_id="NP_010305.1"
                     /db_xref="GI:6320225"
                     /db_xref="SGD:S000002429"
                     /db_xref="GeneID:851585"
                     /translation="MNVTVTVYDKNVKYRLEENIKNNKGPSNDDQPAYNNESKSTDGS
                     DYAMFPTNIKYIFEDNNDELVDSSDAALTAGIDKVGDELENVIIVQLDESGSLEDITL
                     ISDQYELLSHRTNSLSLEENQMRTLSSHGDDKSNDEEEELSVDSDRFRVDSDIELDVI
                     SQFCDLSPFLRDLSLNDLIKLYVTQNEQLQMLSNSV"
     gene            complement(488797..488870)
                     /locus_tag="tV(UAC)D"
                     /db_xref="GeneID:851586"
     tRNA            complement(488797..488870)
                     /locus_tag="tV(UAC)D"
                     /product="tRNA-Val"
                     /note="Valine tRNA (tRNA-Val), predicted by tRNAscan-SE
                     analysis"
                     /db_xref="SGD:S000006770"
                     /db_xref="GeneID:851586"
     gene            <489508..>490896
                     /gene="SES1"
                     /locus_tag="YDR023W"
                     /db_xref="GeneID:851587"
     mRNA            <489508..>490896
                     /gene="SES1"
                     /locus_tag="YDR023W"
                     /product="serine--tRNA ligase SES1"
                     /transcript_id="NM_001180331.1"
                     /db_xref="GI:296143377"
                     /db_xref="GeneID:851587"
     CDS             489508..490896
                     /gene="SES1"
                     /locus_tag="YDR023W"
                     /EC_number="6.1.1.11"
                     /note="Cytosolic seryl-tRNA synthetase; class II
                     aminoacyl-tRNA synthetase that aminoacylates tRNA(Ser),
                     displays tRNA-dependent amino acid recognition which
                     enhances discrimination of the serine substrate, interacts
                     with peroxin Pex21p"
                     /codon_start=1
                     /product="serine--tRNA ligase SES1"
                     /protein_id="NP_010306.1"
                     /db_xref="GI:6320226"
                     /db_xref="SGD:S000002430"
                     /db_xref="GeneID:851587"
                     /translation="MLDINQFIEDKGGNPELIRQSQKARNASVEIVDEIISDYKDWVK
                     TRFELDELNKKFNKLQKDIGLKFKNKEDASGLLAEKEKLTQQKKELTEKEQQEDKDLK
                     KKVFQVGNIVHPSVVVSNDEENNELVRTWKPEDLEAVGPIASVTGKPASLSHHEILLR
                     LDGYDPDRGVKICGHRGYFFRNYGVFLNQALINYGLQFLAAKGYIPLQAPVMMNKELM
                     SKTAQLSEFDEELYKVIDGEDEKYLIATSEQPISAYHSGEWFEKPQEQLPIHYVGYSS
                     CFRREAGSHGKDAWGVFRVHAFEKIEQFVITEPEKSWEEFEKMISYSEEFYKSLKLPY
                     RIVGIVSGELNNAAAKKYDLEAWFPYQKEYKELVSCSNCTDYQSRNLEIRCGIKKMGD
                     REKKYVHCLNSTLAATQRALCCILENYQTEDGLVVPEVLRKYIPGEPEFLPFVNELPK
                     NSTSSKDKKKKN"
     gene            <491515..>492324
                     /gene="RPS11A"
                     /locus_tag="YDR025W"
                     /db_xref="GeneID:851589"
     mRNA            join(<491515..491559,491899..>492324)
                     /gene="RPS11A"
                     /locus_tag="YDR025W"
                     /product="ribosomal 40S subunit protein S11A"
                     /transcript_id="NM_001180333.3"
                     /db_xref="GI:398365070"
                     /db_xref="GeneID:851589"
     CDS             join(491515..491559,491899..492324)
                     /gene="RPS11A"
                     /locus_tag="YDR025W"
                     /note="Protein component of the small (40S) ribosomal
                     subunit; homologous to mammalian ribosomal protein S11 and
                     bacterial S17; N-terminally propionylated in vivo; RPS11A
                     has a paralog, RPS11B, that arose from the whole genome
                     duplication"
                     /codon_start=1
                     /product="ribosomal 40S subunit protein S11A"
                     /protein_id="NP_010308.3"
                     /db_xref="GI:398365071"
                     /db_xref="SGD:S000002432"
                     /db_xref="GeneID:851589"
                     /translation="MSTELTVQSERAFQKQPHIFNNPKVKTSKRTKRWYKNAGLGFKT
                     PKTAIEGSYIDKKCPFTGLVSIRGKILTGTVVSTKMHRTIVIRRAYLHYIPKYNRYEK
                     RHKNVPVHVSPAFRVQVGDIVTVGQCRPISKTVRFNVVKVSAAAGKANKQFAKF"
     gene            complement(<492556..>494268)
                     /gene="NSI1"
                     /locus_tag="YDR026C"
                     /db_xref="GeneID:851590"
     mRNA            complement(<492556..>494268)
                     /gene="NSI1"
                     /locus_tag="YDR026C"
                     /product="Nsi1p"
                     /transcript_id="NM_001180334.3"
                     /db_xref="GI:398365076"
                     /db_xref="GeneID:851590"
     CDS             complement(492556..494268)
                     /gene="NSI1"
                     /locus_tag="YDR026C"
                     /note="RNA polymerase I termination factor; binds to rDNA
                     terminator element, required for efficient Pol I
                     termination; required for rDNA silencing at NTS1;
                     facilities association of Sir2p with NTS1, contributes to
                     rDNA stability and cell longevity; interacts physically
                     with Fob1p and RENT subunits, Sir2p and Net1p; may
                     interact with ribosomes, based on co-purification
                     experiments; Myb-like DNA-binding protein; NSI1 has a
                     paralog, REB1, that arose from the whole genome
                     duplication"
                     /codon_start=1
                     /product="Nsi1p"
                     /protein_id="NP_010309.3"
                     /db_xref="GI:398365077"
                     /db_xref="SGD:S000002433"
                     /db_xref="GeneID:851590"
                     /translation="MDSVSNLKSTNFQNNNDPKESVEEAVLRYVGVDLKNHIKKTKKK
                     LKKQKKRKHGSKMSHEDEDTDMDWYLKTSGSKDLRKVDDIEPNSVAVAAVAAAYNSSM
                     REKDKRSCHKKSSNSRSERKKHRKRKSSKERKAKIKMVLDPQLTTLDDGITTTAFLPD
                     DLIAETAFDKYVDTEKAYLAKHPSKSLEVNEDDKENNFNNNSSTLVRIYTDLEGIPND
                     GSYIKRTPKIPEKDVKSDDLILAPEENNGDTALLRSDIVKASVIDGAITKSIGKKFTP
                     SEENALDQFIEEYMKIRGLDRRQMCERIWSTDGVIRDGFWANISKVLPYRTRSSIYKH
                     IRRKYHIFEQRGKWTPEEDQELARLCLEKEGHWTEVGKLLGRMPEDCRDRWRNYMKCG
                     SKRGSKRWSKEEEELLTTVVNEMIEEAHQYQRMKALEAANKNDRYNQMYSRGPKGKRI
                     SDNPTFKDMINWTVVSERMSGTRSRIQCRYKWNKLVTDEAARSMLSIPVSERKWLLER
                     LKQLPKTSYSNIDWNSIATYKPGYPRTGLELRLCYEQMREKIHDFKGRSTAEIIDSLL
                     EQIN"
     gene            complement(<494649..>497318)
                     /gene="VPS54"
                     /locus_tag="YDR027C"
                     /gene_synonym="CGP1; LUV1; TCS3"
                     /db_xref="GeneID:851591"
     mRNA            complement(<494649..>497318)
                     /gene="VPS54"
                     /locus_tag="YDR027C"
                     /gene_synonym="CGP1; LUV1; TCS3"
                     /product="Vps54p"
                     /transcript_id="NM_001180335.1"
                     /db_xref="GI:296143380"
                     /db_xref="GeneID:851591"
     CDS             complement(494649..497318)
                     /gene="VPS54"
                     /locus_tag="YDR027C"
                     /gene_synonym="CGP1; LUV1; TCS3"
                     /note="Component of the GARP (Golgi-associated retrograde
                     protein) complex; GARP is required for the recycling of
                     proteins from endosomes to the late Golgi, and for mitosis
                     after DNA damage induced checkpoint arrest; potentially
                     phosphorylated by Cdc28p; members of the GARP complex are
                     Vps51p-Vps52p-Vps53p-Vps54p"
                     /codon_start=1
                     /product="Vps54p"
                     /protein_id="NP_010310.1"
                     /db_xref="GI:6320230"
                     /db_xref="SGD:S000002434"
                     /db_xref="GeneID:851591"
                     /translation="MSISETPHNKSQGLQKAAGRPKIVVPEGSPSRNSDSGSFTIEGD
                     TSLNDDLLSISGSVTPRARRSSRLSLDSITPRRSFDSRTLSVANSRSFGFENETHSGS
                     MDFSPLGNNSIYEIVMNTRRKNWLNYPTVADIPQVSLSKNDLDDHWKTHVIEYVKNIK
                     SDYQIFQSTNNIRNMNQMEQLKELREGENMHEESFEANLRQGDAELINSIPDFYFSDK
                     FQLDNPRTFHKVLDAIDLFLTKLDMKRQAERDEAFSELRDRLNDFLDIVETLLVTEIS
                     KSSHKFFHALSEVDNIQKRALDTMSELKELAQNIKTIDAENIRKKISHLEMIFKRKNV
                     EKLEQGLLQAKLVLNKTDECKSMYEENKLDNCLELIKSIDYLIKGDDSINEDVQSWTR
                     CWPYKLSNLRTIPALSATREFLTNMKIEIGGKFSLQLSILLIDDLRSFCKSIKPKETL
                     HRIQTGSNDKKQTIFTDNFSSKITELIVRLNRCEELTSAFDLYREKSITELKSIIKIY
                     LPTENAHADNNHDEKHLNNGSTSGSKLSRLIKEQTPAEFQSMLVNIFTHALEALRRLY
                     GHQKLLLDISLNELASVKSPNENQHNMITQLDIRTGINEIIRIIQLRTGKIIAVRREL
                     NLSLRYDYFLKFYAICVIFIQECEVLSGEFLTKYLSNVLASQIKHYANAQSSKNYRNI
                     KKKIDAEEWIPYIVDSSIQSDVNDIVSSIDIDPLSWTTILDMVGGSHDCENGRSEDKE
                     KDEGNETYQGHRKSVVVGDKTFVASSSLLATIEVIKELMVLSINLPSIYLSNFEKLCY
                     DALQYYNSSAMASVTQPGNSLLKTGRNLSIMGESLDCLAEFVIIVQRFYQRLSNSNRD
                     FEPFDASHYTTLLGQFQASSNKIYMANAPPPPV"
     gene            complement(<497835..>500879)
                     /gene="REG1"
                     /locus_tag="YDR028C"
                     /gene_synonym="HEX2; PZF240; SPP43; SRN1"
                     /db_xref="GeneID:851592"
     mRNA            complement(<497835..>500879)
                     /gene="REG1"
                     /locus_tag="YDR028C"
                     /gene_synonym="HEX2; PZF240; SPP43; SRN1"
                     /product="Reg1p"
                     /transcript_id="NM_001180336.1"
                     /db_xref="GI:296143381"
                     /db_xref="GeneID:851592"
     CDS             complement(497835..500879)
                     /gene="REG1"
                     /locus_tag="YDR028C"
                     /gene_synonym="HEX2; PZF240; SPP43; SRN1"
                     /note="Regulatory subunit of type 1 protein phosphatase
                     Glc7p; involved in negative regulation of
                     glucose-repressible genes; involved in regulation of the
                     nucleocytoplasmic shuttling of Hxk2p; REG1 has a paralog,
                     REG2, that arose from the whole genome duplication"
                     /codon_start=1
                     /product="Reg1p"
                     /protein_id="NP_010311.1"
                     /db_xref="GI:6320231"
                     /db_xref="SGD:S000002435"
                     /db_xref="GeneID:851592"
                     /translation="MSTNLANYFAGKKDIENEHVNRNASHESNSKSDVKISGNDNDND
                     EDMGPSVSMAVQAKNDDDFHKSTFNLKRTRSMGLLDEYIDPTKKLLGRSDDLYDNDNE
                     YYDNSSNNSSSNSSDDDYDDGYQEHSTSVSPPPADNDSYLIPQDDNDVVVEPERHVDY
                     LSHEWKESEISNSWKYIILKKKKRDVDLVNAARLENASWRTWAKARNNLKTVSPEVVN
                     WSKDSDVTWLYGPIVRDSEGNAQSEEEHDLERGYGSDDENSKRISMPTKNSKSIAAAP
                     KPILKKRTVTEIIEDNALWKLNEARKHMTEMKHASVIMDPNGNKNVHDDFDALAAQVN
                     AQYYHYPKESNSSVSLKSQHSDKKDNSTIPNPVGENSNGGGDKGEEDLHLKSALHVQN
                     NRSTAQSNKSILENSTNDRKANLDQNLNSPDNNRFPSSTSSSNRDNENNSMGLSSILT
                     SNPSEKSNKPTKNRHIHFNDRVEQCMALRYPASQSEDDESDDENKQYVDVNNNANVTT
                     INNNRTPLLAIQHKSIPINSATEHLNKNTSDDDTSSQSSSSSHSDDEEHGGLYINARF
                     SRRSDSGVHSPITDNSSVASSTTSRAHVRPIIKLLPDTTLNYGSDEESDNGEFNGYGN
                     AVSHNVNTSRGYDYIYDYNSVYTGDTSSFLPVDSCDIVDVPEGMDLQTAIADDNASNY
                     EFNNAVESKEKHVPQLHKASANNTTRQHGSHMLLYDDDNYSSSSDSEQQFIEDSQYNS
                     SDDEEEEDDDDQEVDDNHDEGLSLRRTLSLGKSGSTNSLYDLAQPSLSSATPQQKNPT
                     NFTGGKTDVDKDAQLAVRPYPLKRNSSSGNFIFNSDSEEESSSEEEQRPLPANSQLVN
                     RSVLKGSVTPANISSQKKKALPKQPKASDSSQSFRIVNNTPSPAEVGASDVAIEGYFS
                     PRNESIKSVVSGGNMMDHQDHSEMDTLAKGFENCHINNASKLKDKKVDSVQTTRKEAS
                     LTDSSNESLHKVVQNARGMASKYLHSWKKSDVKPQENGNDSS"
     gene            complement(<501753..>503273)
                     /gene="RAD28"
                     /locus_tag="YDR030C"
                     /db_xref="GeneID:851594"
     mRNA            complement(<501753..>503273)
                     /gene="RAD28"
                     /locus_tag="YDR030C"
                     /product="Rad28p"
                     /transcript_id="NM_001180338.3"
                     /db_xref="GI:398365096"
                     /db_xref="GeneID:851594"
     CDS             complement(501753..503273)
                     /gene="RAD28"
                     /locus_tag="YDR030C"
                     /note="Protein involved in DNA repair; related to the
                     human CSA protein that is involved in
                     transcription-coupled repair nucleotide excision repair"
                     /codon_start=1
                     /product="Rad28p"
                     /protein_id="NP_010313.3"
                     /db_xref="GI:398365097"
                     /db_xref="SGD:S000002437"
                     /db_xref="GeneID:851594"
                     /translation="MDPFLEFRVGNISLNEFYRRTIQSEFERILEDPLSNMKNYRFSK
                     QSNYSTKEKTPLSIGVNCLDIDDTGQVLLGGGDDGSLSIWGLDESLHRNDEGEQELIN
                     KRLNYIKRQPHQSDDEPAQIMGYKNKRTRINDNNTMRLVHSFQTQRNKYRMYRQSSAA
                     VPVQRSHISNKTDSPIGFSETLSETDSEASISHHKYGITTLKWYKADNGMFFTGSNDK
                     TVKIWDTNRFEAVQDINLGYKINQIDNNVVDDSSLLVVASEDYYPRLIDLRTMNSGVT
                     ALGMGNQTRMQSEILCCKFNPVREQIIACGDMEGGVKLWDLRMRNRLYSELKRNKNRF
                     KTINNDDNDDQSDVYFSSNQSKAHLRCCSDIVWNSEGSELCSVGMDGKLNVWRPFTEI
                     LQPEGLASYSQLGTQDLSRIKYKKRVSRRLLWFDKFLLCITDNGEVEIYNTEEKKLWN
                     KLEYPMVNQVKKNQASHCQFSSMIVQTNIMNSVGLKLFFGTNNNTVSDGGSIFECS"
     gene            <503498..>503863
                     /gene="MIX14"
                     /locus_tag="YDR031W"
                     /gene_synonym="MIC14"
                     /db_xref="GeneID:851595"
     mRNA            <503498..>503863
                     /gene="MIX14"
                     /locus_tag="YDR031W"
                     /gene_synonym="MIC14"
                     /product="Mix14p"
                     /transcript_id="NM_001180339.3"
                     /db_xref="GI:398365108"
                     /db_xref="GeneID:851595"
     CDS             503498..503863
                     /gene="MIX14"
                     /locus_tag="YDR031W"
                     /gene_synonym="MIC14"
                     /note="Mitochondrial intermembrane space hypothetical
                     protein; required for normal oxygen consumption; contains
                     twin cysteine-x9-cysteine motifs; protein abundance
                     increases in response to DNA replication stress"
                     /codon_start=1
                     /product="Mix14p"
                     /protein_id="NP_010314.4"
                     /db_xref="GI:398365109"
                     /db_xref="SGD:S000002438"
                     /db_xref="GeneID:851595"
                     /translation="MSDILDEIVIEDVVANCPQEFLQYHKCIRDNEENPGKCKDGRMI
                     LSTCIREKVPSVKSIMSECSEPMKKYDQCIRDNMGTRTINENCLGFLQDLRKCAELQV
                     KNKNIKPSINGVNLELIKD"
     gene            complement(<504099..>504695)
                     /gene="PST2"
                     /locus_tag="YDR032C"
                     /db_xref="GeneID:851596"
     mRNA            complement(<504099..>504695)
                     /gene="PST2"
                     /locus_tag="YDR032C"
                     /product="Pst2p"
                     /transcript_id="NM_001180340.1"
                     /db_xref="GI:296143384"
                     /db_xref="GeneID:851596"
     CDS             complement(504099..504695)
                     /gene="PST2"
                     /locus_tag="YDR032C"
                     /note="Protein with similarity to a family of
                     flavodoxin-like proteins; induced by oxidative stress in a
                     Yap1p dependent manner; the authentic, non-tagged protein
                     is detected in highly purified mitochondria in
                     high-throughput studies; protein abundance increases in
                     response to DNA replication stress; PST2 has a paralog,
                     RFS1, that arose from the whole genome duplication"
                     /codon_start=1
                     /product="Pst2p"
                     /protein_id="NP_010315.1"
                     /db_xref="GI:6320235"
                     /db_xref="SGD:S000002439"
                     /db_xref="GeneID:851596"
                     /translation="MPRVAIIIYTLYGHVAATAEAEKKGIEAAGGSADIYQVEETLSP
                     EVVKALGGAPKPDYPIATQDTLTEYDAFLFGIPTRFGNFPAQWKAFWDRTGGLWAKGA
                     LHGKVAGCFVSTGTGGGNEATIMNSLSTLAHHGIIFVPLGYKNVFAELTNMDEVHGGS
                     PWGAGTIAGSDGSRSPSALELQVHEIQGKTFYETVAKF"
     rep_origin      505343..505584
                     /note="ARS450;
                     Autonomously Replicating Sequence"
                     /db_xref="SGD:S000119069"
     gene            <508147..>509109
                     /gene="MRH1"
                     /locus_tag="YDR033W"
                     /db_xref="GeneID:851597"
     mRNA            <508147..>509109
                     /gene="MRH1"
                     /locus_tag="YDR033W"
                     /product="Mrh1p"
                     /transcript_id="NM_001180341.1"
                     /db_xref="GI:296143385"
                     /db_xref="GeneID:851597"
     CDS             508147..509109
                     /gene="MRH1"
                     /locus_tag="YDR033W"
                     /note="Protein that localizes primarily to the plasma
                     membrane; also found at the nuclear envelope; the
                     authentic, non-tagged protein is detected in mitochondria
                     in a phosphorylated state; MRH1 has a paralog, YRO2, that
                     arose from the whole genome duplication"
                     /codon_start=1
                     /product="Mrh1p"
                     /protein_id="NP_010316.1"
                     /db_xref="GI:6320236"
                     /db_xref="SGD:S000002440"
                     /db_xref="GeneID:851597"
                     /translation="MSTFETLIKRGGNEAIKINPPTGADFHITSRGSDWFWTCFCCYL
                     LFGLILTFLMFRKPVNDRFFYLTGIAPNFFMCIAYFTMASNLGWIPVKAKYNHVQTST
                     QKEHPGYRQIFYSRFVGWFLALPWPIIQICMLAGTPFWQMAFNVCITEFFTVCWLIAA
                     CVHSTYKWGYYTIGLGAAIVVSISVMTTSYNLVKQRDNDIRLTFLVFFSIIMFLWIIA
                     YPTCFGITDGGNVLQPDSAGIFYGIIDLILMCFIPTLLVPIANHFGADKLGYHFGPSD
                     AEAVMAPKAPVASPRPAATPNLSKDKKKKSKKSKKSKKSKKSEE"
     gene            complement(<509737..>512109)
                     /gene="LYS14"
                     /locus_tag="YDR034C"
                     /db_xref="GeneID:851598"
     mRNA            complement(<509737..>512109)
                     /gene="LYS14"
                     /locus_tag="YDR034C"
                     /product="Lys14p"
                     /transcript_id="NM_001180342.3"
                     /db_xref="GI:398365128"
                     /db_xref="GeneID:851598"
     CDS             complement(509737..512109)
                     /gene="LYS14"
                     /locus_tag="YDR034C"
                     /note="Transcriptional activator involved in regulating
                     lysine biosynthesis; involved in the regulation of genes
                     of the lysine biosynthesis pathway; requires
                     2-aminoadipate semialdehyde as co-inducer"
                     /codon_start=1
                     /product="Lys14p"
                     /protein_id="NP_010317.3"
                     /db_xref="GI:398365129"
                     /db_xref="SGD:S000002441"
                     /db_xref="GeneID:851598"
                     /translation="MFESVNLDENSPEDRELAKVLSPPGSYLSPASLDSGSSFTNSGT
                     STSCFEPKNNLPSLSFLNARAGSLGGIFNHKQMTSPSNSNIGGENVESTTSSNDGSNE
                     NAGHPTTSEQDQNADHPTISQADDNGHSSLTPNPAVTSTVTDKKGNTVKRKYSRNGCS
                     ECKRRRMKCDETKPTCWQCARLNRQCVYVLNPKNKKRRTSNAQRVKEFRKHSTSLDND
                     HNNARKRQHSSCKAEKKKKVRQNLSEDTTDPKPITDNGKNVPLDEIESLEIPNLDLTT
                     TMNGYDVNLLMQNLNDMVNMKLHDSYLLNEELKGLDLPDLDIPELLPASNVNSSVPIS
                     FLVNNVITFNTKLSSFKLGGIHDKYLKIFYYDCLDSIAPFFQNQGNPLRDILLSFAKN
                     EAYLLSSILATGASIAYRKSNNLEDERNYCAYLSHCLSLLGEQFKNESNVLNRIEPII
                     LTVIMLAWDCIYSMNSQWRSHLKGVTDLFKKINAGNSSKVLNVAKCWFKVMETFASIS
                     TVFGGSLIDNNDLDAIFDPYDYQYVDSLKFLNIMTPLNEFNLLRGHKEDFDLVIKEVF
                     KSLNTIRSTEKNYFSKEEGLFTKKLDYLLLSSQTSSEKSKDQISYFNTQKILVEIDKQ
                     LDYEFIDKSGIIPSDNQSHPRISNIHDNAIDMVTLKNGEEVAISWYDISHQTQVLSFL
                     LIVLLKLLGMPKESSTIQQVVKKIMSFFKFLDSDSPPQNSRTCYSNFAVLIAGLNAMD
                     EETRAIVKRYYKINGGKFQKLTEHNLNRLEKVWYGKNQNYRLEEQDVLTW"
     LTR             complement(512986..513258)
                     /note="Ty1 LTR"
                     /db_xref="SGD:S000006844"
     LTR             complement(513259..513590)
                     /note="Ty1 LTR"
                     /db_xref="SGD:S000006845"
     mobile_element  complement(513692..519647)
                     /note="YDRCTy2-1; Ty2 element, LTR retrotransposon of the
                     Copia (Pseudoviridae) group; contains co-transcribed genes
                     TYA Gag and TYB Pol, encoding proteins involved in
                     structure and function of virus-like particles, flanked by
                     two direct repeats"
                     /mobile_element_type="retrotransposon:YDRCTy2-1"
                     /db_xref="SGD:S000006862"
     LTR             complement(513692..514020)
                     /note="Ty2 LTR"
                     /db_xref="SGD:S000006846"
     gene            complement(<514043..>519356)
                     /locus_tag="YDR034C-D"
                     /db_xref="GeneID:851599"
     mRNA            complement(join(<514043..518062,518064..>519356))
                     /locus_tag="YDR034C-D"
                     /product="gag-pol fusion protein"
                     /transcript_id="NM_001184379.3"
                     /db_xref="GI:398365134"
                     /db_xref="GeneID:851599"
     CDS             complement(join(514043..518062,518064..519356))
                     /locus_tag="YDR034C-D"
                     /EC_number="3.4.23.-"
                     /EC_number="3.1.26.4"
                     /EC_number="2.7.7.7"
                     /EC_number="2.7.7.49"
                     /ribosomal_slippage
                     /note="Retrotransposon TYA Gag and TYB Pol genes;
                     transcribed/translated as one unit; polyprotein is
                     processed to make a nucleocapsid-like protein (Gag),
                     reverse transcriptase (RT), protease (PR), and integrase
                     (IN); similar to retroviral genes"
                     /codon_start=1
                     /product="gag-pol fusion protein"
                     /protein_id="NP_058138.3"
                     /db_xref="GI:398365135"
                     /db_xref="SGD:S000007345"
                     /db_xref="GeneID:851599"
                     /translation="MESQQLSQNSPNLHGSAYASVTSKEVPSNQDPLAVSASNLPEFD
                     RDSTKVNSQQETTPGTSAVPENHHHVSPQPASVPPPQNGQYQQHGMMTPNKAMASNWA
                     HYQQPSMMTCSHYQTSPAYYQPDPHYPLPQYIPPLSTSSPDPIDLKNQHSEIPQAKTK
                     VGNNVLPPHTLTSEENFSTWVKFYIRFLKNSNLGDIIPNDQGEIKRQMTYEEHAYIYN
                     TFQAFAPFHLLPTWVKQILEINYADILTVLCKSVSKMQTNNQELKDWIALANLEYDGS
                     TSADTFEITVSTIIQRLKENNINVSDRLACQLILKGLSGDFKYLRNQYRTKTNMKLSQ
                     LFAEIQLIYDENKIMNLNKPSQYKQHSEYKNVSRTSPNTTNTKVTTRNYQRTNSSKPR
                     AAKAHNIATSSKFSRVNNDHINESTVSSQYLSDDNELSLGQQQKESKPTHTIDSNDEL
                     PDHLLIDSGASQTLVRSAHYLHHATPNSEINIVDAQKQDIPINAIGNLHFNFQNGTKT
                     SIKALHTPNIAYDLLSLSELANQNITACFTRNTLERSDGTVLAPIVKHGDFYWLSKKY
                     LIPSHISKLTINNVNKSKSVNKYPYPLIHRMLGHANFRSIQKSLKKNAVTYLKESDIE
                     WSNASTYQCPDCLIGKSTKHRHVKGSRLKYQESYEPFQYLHTDIFGPVHHLPKSAPSY
                     FISFTDEKTRFQWVYPLHDRREESILNVFTSILAFIKNQFNARVLVIQMDRGSEYTNK
                     TLHKFFTNRGITACYTTTADSRAHGVAERLNRTLLNDCRTLLHCSGLPNHLWFSAVEF
                     STIIRNSLVSPKNDKSARQHAGLAGLDITTILPFGQPVIVNNHNPDSKIHPRGIPGYA
                     LHPSRNSYGYIIYLPSLKKTVDTTNYVILQDKQSKLDQFNYDTLTFDDDLNRLTAHNQ
                     SFIEKNETEQSYDQNTESDHDYQSEIEINSDPLVNDFSSQSINPLQLDKEPVQKVRAP
                     KEVDADISEYNILPSTIRSRTPHIINKESTEMGGTIESDTTSPRHSSTFTARNQKRPG
                     SPNDMIDLTSQDRVNYGLENIKTTRLGGTEEPYIQRNSDTNIKYRTTNSTPSIDDRSS
                     NSESTTPIISIETKAACDNTPSIDTDPPEYRSSDHATPNIMPDKSSKNVTADSILDDL
                     PLPDLTNKSPTDTSDVSKDIPHIHSRQTNSSLGGMDDSNVLTTTKSKKRSLEDNETEI
                     EVSRDTWNNKNMRSLEPPRSKKRINLIAAIKGVKSIKPVRTTLRYDEAITYNEDNKEK
                     DRYIEAYHKEINQLLRMNTWDTNKYYDRNDIDPKKVINSMFIFNKKRDGTHKARFVAR
                     GDIQHPDTYDSDMQSNTVHHYALMTSLSIALDNDYYITQLDISSAYLYADIKEELYIR
                     PPPHLGLNDKLLRLRKSLYGLKQSGANWYETIKSYLINCCDMQEVRGWSCVFKNSQVT
                     ICLFVDDMILFSKDLNANKKIITTLKKQYDTKIINLGEGDNEIQYDILGLEIKYQRSK
                     YMKLGMEKSLTEKLPKLNVPLNPKGKKLRAPGQPGHYIDQDELEIDEDEYKEKVHEMQ
                     KLIGLASYVGYKFRFDLLYYINTLAQHILFPSRQVLDMTYELIQFMWDTRDKQLIWHK
                     NKPTKPDNKLVAISDASYGNQPYYKSQIGNIFLLNGKVIGGKSTKASLTCTSTTEAEI
                     HAVSEAIPLLNNLSHLVQELNKKPIIKGLLTDSRSTISIIKSTNEEKFRNRFFGTKAM
                     RLRDEVSGNNLYVYYIETKKNIADVMTKPLPIKTFKLLTNKWIH"
     gene            complement(<518040..>519356)
                     /locus_tag="YDR034C-C"
                     /db_xref="GeneID:851600"
     mRNA            complement(<518040..>519356)
                     /locus_tag="YDR034C-C"
                     /product="gag protein"
                     /transcript_id="NM_001184378.1"
                     /db_xref="GI:296143388"
                     /db_xref="GeneID:851600"
     CDS             complement(518040..519356)
                     /locus_tag="YDR034C-C"
                     /note="Retrotransposon TYA Gag gene co-transcribed with
                     TYB Pol; translated as TYA or TYA-TYB polyprotein; Gag is
                     a nucleocapsid protein that is the structural constituent
                     of virus-like particles (VLPs); similar to retroviral Gag"
                     /codon_start=1
                     /product="gag protein"
                     /protein_id="NP_058139.1"
                     /db_xref="GI:7839149"
                     /db_xref="SGD:S000007344"
                     /db_xref="GeneID:851600"
                     /translation="MESQQLSQNSPNLHGSAYASVTSKEVPSNQDPLAVSASNLPEFD
                     RDSTKVNSQQETTPGTSAVPENHHHVSPQPASVPPPQNGQYQQHGMMTPNKAMASNWA
                     HYQQPSMMTCSHYQTSPAYYQPDPHYPLPQYIPPLSTSSPDPIDLKNQHSEIPQAKTK
                     VGNNVLPPHTLTSEENFSTWVKFYIRFLKNSNLGDIIPNDQGEIKRQMTYEEHAYIYN
                     TFQAFAPFHLLPTWVKQILEINYADILTVLCKSVSKMQTNNQELKDWIALANLEYDGS
                     TSADTFEITVSTIIQRLKENNINVSDRLACQLILKGLSGDFKYLRNQYRTKTNMKLSQ
                     LFAEIQLIYDENKIMNLNKPSQYKQHSEYKNVSRTSPNTTNTKVTTRNYQRTNSSKPR
                     AAKAHNIATSSKFSRVNNDHINESTVSSQYLSDDNELSLRPATERI"
     LTR             complement(519316..519647)
                     /note="Ty2 LTR"
                     /db_xref="SGD:S000006847"
     gene            519743..519826
                     /locus_tag="tL(UAA)D"
                     /db_xref="GeneID:851601"
     tRNA            519743..519826
                     /locus_tag="tL(UAA)D"
                     /product="tRNA-Leu"
                     /note="Leucine tRNA (tRNA-Leu), predicted by tRNAscan-SE
                     analysis"
                     /db_xref="SGD:S000006649"
                     /db_xref="GeneID:851601"
     LTR             complement(520173..520475)
                     /note="Ty1 LTR"
                     /db_xref="SGD:S000006848"
     LTR             520477..520805
                     /note="Ty1 LTR"
                     /db_xref="SGD:S000006863"
     gene            complement(<520516..>520692)
                     /locus_tag="YDR034C-A"
                     /db_xref="GeneID:851602"
     mRNA            complement(<520516..>520692)
                     /locus_tag="YDR034C-A"
                     /product="hypothetical protein"
                     /transcript_id="NM_001184326.1"
                     /db_xref="GI:296143389"
                     /db_xref="GeneID:851602"
     CDS             complement(520516..520692)
                     /locus_tag="YDR034C-A"
                     /note="hypothetical protein; contained within the solo Ty1
                     LTR element YDRWdelta7"
                     /codon_start=1
                     /product="hypothetical protein"
                     /protein_id="NP_010318.1"
                     /db_xref="GI:6320238"
                     /db_xref="SGD:S000007233"
                     /db_xref="GeneID:851602"
                     /translation="MESIFLHANITIIPHSVLYVSLSYYIINPCVSVSTNLDDYFSSF
                     VSSSNTVYDNILVT"
     LTR             complement(520806..520833)
                     /note="Ty1 LTR"
                     /db_xref="SGD:S000006849"
     gene            520972..521043
                     /locus_tag="tQ(UUG)D1"
                     /db_xref="GeneID:851603"
     tRNA            520972..521043
                     /locus_tag="tQ(UUG)D1"
                     /product="tRNA-Gln"
                     /note="Glutamine tRNA (tRNA-Gln), predicted by tRNAscan-SE
                     analysis; thiolation of uridine at wobble position (34)
                     requires Ncs6p"
                     /db_xref="SGD:S000006693"
                     /db_xref="GeneID:851603"
     gene            <521314..>521469
                     /locus_tag="YDR034W-B"
                     /db_xref="GeneID:851604"
     mRNA            <521314..>521469
                     /locus_tag="YDR034W-B"
                     /product="hypothetical protein"
                     /transcript_id="NM_001184327.3"
                     /db_xref="GI:398365164"
                     /db_xref="GeneID:851604"
     CDS             521314..521469
                     /locus_tag="YDR034W-B"
                     /note="Predicted tail-anchored plasma membrane protein;
                     contains conserved CYSTM module; related proteins in other
                     organisms may be involved in response to stress; green
                     fluorescent protein (GFP)-fusion protein localizes to the
                     cell periphery; YDR034W-B has a paralog, YBR056W-A, that
                     arose from the whole genome duplication"
                     /codon_start=1
                     /product="hypothetical protein"
                     /protein_id="NP_010319.3"
                     /db_xref="GI:398365165"
                     /db_xref="SGD:S000007234"
                     /db_xref="GeneID:851604"
                     /translation="MRHHQNMHYAPQQQPVYVQQPPPRRESGGCCRTCCHFLCCLCLI
                     NLCCDVF"
     gene            <521816..>522928
                     /gene="ARO3"
                     /locus_tag="YDR035W"
                     /db_xref="GeneID:851605"
     mRNA            <521816..>522928
                     /gene="ARO3"
                     /locus_tag="YDR035W"
                     /product="3-deoxy-7-phosphoheptulonate synthase ARO3"
                     /transcript_id="NM_001180343.3"
                     /db_xref="GI:398365166"
                     /db_xref="GeneID:851605"
     CDS             521816..522928
                     /gene="ARO3"
                     /locus_tag="YDR035W"
                     /EC_number="2.5.1.54"
                     /note="3-deoxy-D-arabino-heptulosonate-7-phosphate (DAHP)
                     synthase; catalyzes the first step in aromatic amino acid
                     biosynthesis and is feedback-inhibited by phenylalanine or
                     high concentration of tyrosine or tryptophan"
                     /codon_start=1
                     /product="3-deoxy-7-phosphoheptulonate synthase ARO3"
                     /protein_id="NP_010320.3"
                     /db_xref="GI:398365167"
                     /db_xref="SGD:S000002442"
                     /db_xref="GeneID:851605"
                     /translation="MFIKNDHAGDRKRLEDWRIKGYDPLTPPDLLQHEFPISAKGEEN
                     IIKARDSVCDILNGKDDRLVIVIGPCSLHDPKAAYDYADRLAKISEKLSKDLLIIMRA
                     YLEKPRTTVGWKGLINDPDMNNSFQINKGLRISREMFIKLVEKLPIAGEMLDTISPQF
                     LSDCFSLGAIGARTTESQLHRELASGLSFPIGFKNGTDGGLQVAIDAMRAAAHEHYFL
                     SVTKPGVTAIVGTEGNKDTFLILRGGKNGTNFDKESVQNTKKQLEKAGLTDDSQKRIM
                     IDCSHGNSNKDFKNQPKVAKCIYDQLTEGENSLCGVMIESNINEGRQDIPKEGGREGL
                     KYGCSVTDACIGWESTEQVLELLAEGVRNRRKALKK"
     gene            complement(<523211..>524713)
                     /gene="EHD3"
                     /locus_tag="YDR036C"
                     /db_xref="GeneID:851606"
     mRNA            complement(<523211..>524713)
                     /gene="EHD3"
                     /locus_tag="YDR036C"
                     /product="Ehd3p"
                     /transcript_id="NM_001180344.1"
                     /db_xref="GI:296143392"
                     /db_xref="GeneID:851606"
     CDS             complement(523211..524713)
                     /gene="EHD3"
                     /locus_tag="YDR036C"
                     /EC_number="3.1.2.4"
                     /note="3-hydroxyisobutyryl-CoA hydrolase; member of a
                     family of enoyl-CoA hydratase/isomerases; non-tagged
                     protein is detected in highly purified mitochondria in
                     high-throughput studies; phosphorylated; mutation affects
                     fluid-phase endocytosis"
                     /codon_start=1
                     /product="Ehd3p"
                     /protein_id="NP_010321.1"
                     /db_xref="GI:6320241"
                     /db_xref="SGD:S000002443"
                     /db_xref="GeneID:851606"
                     /translation="MLRNTLKCAQLSSKYGFKTTTRTFMTTQPQLNVTDAPPVLFTVQ
                     DTARVITLNRPKKLNALNAEMSESMFKTLNEYAKSDTTNLVILKSSNRPRSFCAGGDV
                     ATVAIFNFNKEFAKSIKFFTDEYSLNFQIATYLKPIVTFMDGITMGGGVGLSIHTPFR
                     IATENTKWAMPEMDIGFFPDVGSTFALPRIVTLANSNSQMALYLCLTGEVVTGADAYM
                     LGLASHYVSSENLDALQKRLGEISPPFNNDPQSAYFFGMVNESIDEFVSPLPKDYVFK
                     YSNEKLNVIEACFNLSKNGTIEDIMNNLRQYEGSAEGKAFAQEIKTKLLTKSPSSLQI
                     ALRLVQENSRDHIESAIKRDLYTAANMCMNQDSLVEFSEATKHKLIDKQRVPYPWTKK
                     EQLFVSQLTSITSPKPSLPMSLLRNTSNVTWTQYPYHSKYQLPTEQEIAAYIEKRTND
                     DTGAKVTEREVLNHFANVIPSRRGKLGIQSLCKIVCERKCEEVNDGLRWK"
     gene            <525440..>527215
                     /gene="KRS1"
                     /locus_tag="YDR037W"
                     /gene_synonym="GCD5"
                     /db_xref="GeneID:851607"
     mRNA            <525440..>527215
                     /gene="KRS1"
                     /locus_tag="YDR037W"
                     /gene_synonym="GCD5"
                     /product="lysine--tRNA ligase KRS1"
                     /transcript_id="NM_001180345.1"
                     /db_xref="GI:296143393"
                     /db_xref="GeneID:851607"
     CDS             525440..527215
                     /gene="KRS1"
                     /locus_tag="YDR037W"
                     /gene_synonym="GCD5"
                     /EC_number="6.1.1.6"
                     /note="Lysyl-tRNA synthetase"
                     /codon_start=1
                     /product="lysine--tRNA ligase KRS1"
                     /protein_id="NP_010322.1"
                     /db_xref="GI:6320242"
                     /db_xref="SGD:S000002444"
                     /db_xref="GeneID:851607"
                     /translation="MSQQDNVKAAAEGVANLHLDEATGEMVSKSELKKRIKQRQVEAK
                     KAAKKAAAQPKPASKKKTDLFADLDPSQYFETRSRQIQELRKTHEPNPYPHKFHVSIS
                     NPEFLAKYAHLKKGETLPEEKVSIAGRIHAKRESGSKLKFYVLHGDGVEVQLMSQLQD
                     YCDPDSYEKDHDLLKRGDIVGVEGYVGRTQPKKGGEGEVSVFVSRVQLLTPCLHMLPA
                     DHFGFKDQETRYRKRYLDLIMNKDARNRFITRSEIIRYIRRFLDQRKFIEVETPMMNV
                     IAGGATAKPFITHHNDLDMDMYMRIAPELFLKQLVVGGLDRVYEIGRQFRNEGIDMTH
                     NPEFTTCEFYQAYADVYDLMDMTELMFSEMVKEITGSYIIKYHPDPADPAKELELNFS
                     RPWKRINMIEELEKVFNVKFPSGDQLHTAETGEFLKKILVDNKLECPPPLTNARMLDK
                     LVGELEDTCINPTFIFGHPQMMSPLAKYSRDQPGLCERFEVFVATKEICNAYTELNDP
                     FDQRARFEEQARQKDQGDDEAQLVDETFCNALEYGLPPTGGWGCGIDRLAMFLTDSNT
                     IREVLLFPTLKPDVLREEVKKEEEN"
     gene            complement(<527422..>530697)
                     /gene="ENA5"
                     /locus_tag="YDR038C"
                     /db_xref="GeneID:851608"
     mRNA            complement(<527422..>530697)
                     /gene="ENA5"
                     /locus_tag="YDR038C"
                     /product="putative Na(+)-exporting P-type ATPase ENA5"
                     /transcript_id="NM_001180346.3"
                     /db_xref="GI:398365196"
                     /db_xref="GeneID:851608"
     CDS             complement(527422..530697)
                     /gene="ENA5"
                     /locus_tag="YDR038C"
                     /EC_number="3.6.3.7"
                     /note="Protein with similarity to P-type ATPase sodium
                     pumps; member of the Na+ efflux ATPase family"
                     /codon_start=1
                     /product="putative Na(+)-exporting P-type ATPase ENA5"
                     /protein_id="NP_010323.3"
                     /db_xref="GI:398365197"
                     /db_xref="SGD:S000002445"
                     /db_xref="GeneID:851608"
                     /translation="MSEGTVKENNNEEFNAYHTLTTEEAAEFIGTSLTEGLTQDESLR
                     RLKAVGENTLGDDTKIDYKAMVLHQVCNAMIMVLVISMAISFAVRDWITGGVISFVIA
                     VNVLIGLVQEYKATKTMNSLKNLSSPNAHVIRNGKSETINSKDVVPGDICLVKVGDTI
                     PADLRLIETKNFDTDESLLTGESLPVSKDANLVFGKEEETSVGDRLNLAFSSSAVVKG
                     RAKGIVIKTALNSEIGKIAKSLQGDSGLISRDPSKSWLQNTWISTKKVTGAFLGTNVG
                     TPLHRKLSKLAVLLFWIAVLFAIIVMASQKFDVDKRVAIYAICVALSMIPSSLVVVLT
                     ITMSVGAAVMVSRNVIVRKLDSLEALGAVNDICSDKTGTLTQGKMLARQIWIPRFGTI
                     TISNSDDPFNPNEGNVSLIPRFSPYEYSHNEDGDVGILQNFKDRLYEKDLPEDIDMDL
                     FQKWLETATLANIATVFKDDATDCWKAHGDPTEIAIQVFATKMDLPHNALTGEKSTNQ
                     SNENDQSSLSQHNEKPGSAQFEHIAEFPFDSTVKRMSSVYYNNHNETYNIYGKGAFES
                     IISCCSSWYGKDGVKITPLTDCDVETIRKNVYSLSNEGLRVLGFASKSFTKDQVNDDQ
                     LKNITSNRATAESDLVFLGLIGIYDPPRNETAGAVKKFHQAGINVHMLTGDFVGTAKA
                     IAQEVGILPTNLYHYSQEIVDSMVMTGSQFDGLSEEEVDDLPVLPLVIARCSPQTKVR
                     MIEALHRRKKFCAMTGDGVNDSPSLKMANVGIAMGINGSDVSKEASDIVLSDDNFASI
                     LNAVEEGRRMTDNIQKFVLQLLAENVAQALYLIIGLVFRDENGKSVFPLSPVEVLWII
                     VVTSCFPAMGLGLEKAAPDLMDRPPNDSEVGIFTWEVIIDTFAYGIIMTGSCMASFTG
                     SLYGINSGRLGHDCDGTYNSSCRDVYRSRSAAFATMTWCALILAWEVVDMRRSFFRMH
                     PDTDSPVKEFFRSIWGNQFLFWSIIFGFVSAFPVVYIPVINDKVFLHKPIGAEWGLAI
                     AFTIAFWIGAELYKCGKRRYFKTQRAHNSENDLERSSKHDPFEAYSTSTTLQSEINIS
                     VKH"
     gene            complement(<531307..>534582)
                     /gene="ENA2"
                     /locus_tag="YDR039C"
                     /db_xref="GeneID:851609"
     mRNA            complement(<531307..>534582)
                     /gene="ENA2"
                     /locus_tag="YDR039C"
                     /product="Na(+)-exporting P-type ATPase ENA2"
                     /transcript_id="NM_001180347.3"
                     /db_xref="GI:398365206"
                     /db_xref="GeneID:851609"
     CDS             complement(531307..534582)
                     /gene="ENA2"
                     /locus_tag="YDR039C"
                     /EC_number="3.6.3.7"
                     /note="P-type ATPase sodium pump; involved in Na+ efflux
                     to allow salt tolerance; likely not involved in Li+
                     efflux"
                     /codon_start=1
                     /product="Na(+)-exporting P-type ATPase ENA2"
                     /protein_id="NP_010324.3"
                     /db_xref="GI:398365207"
                     /db_xref="SGD:S000002446"
                     /db_xref="GeneID:851609"
                     /translation="MSEGTVKENNNEEFNAYHTLTTEEAAEFIGTSLTEGLTQDESLR
                     RLKAVGENTLGDDTKIDYKAMVLHQVCNAMIMVLVISMAISFAVRDWITGGVISFVIA
                     VNVLIGLVQEYKATKTMNSLKNLSSPNAHVIRNGKSETINSKDVVPGDICLVKVGDTI
                     PADLRLIETKNFDTDESLLTGESLPVSKDANLVFGKEEETSVGDRLNLAFSSSAVVKG
                     RAKGIVIKTALNSEIGKIAKSLQGDSGLISRDPSKSWLQNTWISTKKVTGAFLGTNVG
                     TPLHRKLSKLAVLLFWIAVLFAIIVMASQKFDVDKRVAIYAICVALSMIPSSLVVVLT
                     ITMSVGAAVMVSRNVIVRKLDSLEALGAVNDICSDKTGTLTQGKMLARQIWIPRFGTI
                     TISNSDDPFNPNEGNVSLIPRFSPYEYSHNEDGDVGILQNFKDRLYEKDLPEDIDMDL
                     FQKWLETATLANIATVFKDDATDCWKAHGDPTEIAIQVFATKMDLPHNALTGEKSTNQ
                     SNENDQSSLSQHNEKPGSAQFEHIAEFPFDSTVKRMSSVYYNNHNETYNIYGKGAFES
                     IISCCSSWYGKDGVKITPLTDCDVETIRKNVYSLSNEGLRVLGFASKSFTKDQVNDDQ
                     LKNITSNRATAESDLVFLGLIGIYDPPRNETAGAVKKFHQAGINVHMLTGDFVGTAKA
                     IAQEVGILPTNLYHYSQEIVDSMVMTGSQFDGLSEEEVDDLPVLPLVIARCSPQTKVR
                     MIEALHRRKKFCAMTGDGVNDSPSLKMANVGIAMGINGSDVSKEASDIVLSDDNFASI
                     LNAVEEGRRMTDNIQKFVLQLLAENVAQALYLIIGLVFRDENGKSVFPLSPVEVLWII
                     VVTSCFPAMGLGLEKAAPDLMDRPPHDSEVGIFTWEVIIDTFAYGIIMTGSCMASFTG
                     SLYGINSGRLGHDCDGTYNSSCRDVYRSRSAAFATMTWCALILAWEVVDMRRSFFRMH
                     PDTDSPVKEFFRSIWGNQFLFWSIIFGFVSAFPVVYIPVINDKVFLHKPIGAEWGLAI
                     AFTIAFWIGAELYKCGKRRYFKTQRAHNPENDLESNNKRDPFEAYSTSTTIHTEVNIG
                     IKQ"
     gene            complement(<535192..>538467)
                     /gene="ENA1"
                     /locus_tag="YDR040C"
                     /gene_synonym="HOR6; PMR2"
                     /db_xref="GeneID:851610"
     mRNA            complement(<535192..>538467)
                     /gene="ENA1"
                     /locus_tag="YDR040C"
                     /gene_synonym="HOR6; PMR2"
                     /product="Na(+)/Li(+)-exporting P-type ATPase ENA1"
                     /transcript_id="NM_001180348.1"
                     /db_xref="GI:296143396"
                     /db_xref="GeneID:851610"
     CDS             complement(535192..538467)
                     /gene="ENA1"
                     /locus_tag="YDR040C"
                     /gene_synonym="HOR6; PMR2"
                     /EC_number="3.6.3.7"
                     /note="P-type ATPase sodium pump; involved in Na+ and Li+
                     efflux to allow salt tolerance"
                     /codon_start=1
                     /product="Na(+)/Li(+)-exporting P-type ATPase ENA1"
                     /protein_id="NP_010325.1"
                     /db_xref="GI:6320245"
                     /db_xref="SGD:S000002447"
                     /db_xref="GeneID:851610"
                     /translation="MGEGTTKENNNAEFNAYHTLTAEEAAEFIGTSLTEGLTQDEFVH
                     RLKTVGENTLGDDTKIDYKAMVLHQVCNAMIMVLLISMIISFAMHDWITGGVISFVIA
                     VNVLIGLVQEYKATKTMNSLKNLSSPNAHVIRNGKSETINSKDVVPGDICLVKVGDTI
                     PADLRLIETKNFDTDESLLTGESLPVSKDANLVFGKEEETSVGDRLNLAFSSSAVVKG
                     RAKGIVIKTALNSEIGKIAKSLQGDSGLISRDPSKSWLQNTWISTKKVTGAFLGTNVG
                     TPLHRKLSKLAVLLFWIAVLFAIIVMASQKFDVDKRVAIYAICVALSMIPSSLVVVLT
                     ITMSVGAAVMVSRNVIVRKLDSLEALGAVNDICSDKTGTLTQGKMLARQIWIPRFGTI
                     TISNSDDPFNPNEGNVSLIPRFSPYEYSHNEDGDVGILQNFKDRLYEKDLPEDIDMDL
                     FQKWLETATLANIATVFKDDATDCWKAHGDPTEIAIQVFATKMDLPHNALTGEKSTNQ
                     SNENDQSSLSQHNEKPGSAQFEHIAEFPFDSTVKRMSSVYYNNHNETYNIYGKGAFES
                     IISCCSSWYGKDGVKITPLTDCDVETIRKNVYSLSNEGLRVLGFASKSFTKDQVNDDQ
                     LKNITSNRATAESDLVFLGLIGIYDPPRNETAGAVKKFHQAGINVHMLTGDFVGTAKA
                     IAQEVGILPTNLYHYSQEIVDSMVMTGSQFDGLSEEEVDDLPVLPLVIARCSPQTKVR
                     MIEALHRRKKFCTMTGDGVNDSPSLKMANVGIAMGINGSDVSKEASDIVLSDDNFASI
                     LNAVEEGRRMTDNIQKFVLQLLAENVAQALYLIIGLVFRDENGKSVFPLSPVEVLWII
                     VVTSCFPAMGLGLEKAAPDLMDRPPHDSEVGIFTWEVIIDTFAYGIIMTGSCMASFTG
                     SLYGINSGRLGHDCDGTYNSSCRDVYRSRSAAFATMTWCALILAWEVVDMRRSFFRMH
                     PDTDSPVKEFFRSIWGNQFLFWSIIFGFVSAFPVVYIPVINDKVFLHKPIGAEWGLAI
                     AFTIAFWIGAELYKCGKRRYFKTQRAHNPENDLESNNKRDPFEAYSTSTTIHTEVNIG
                     IKQ"
     gene            <539803..>540414
                     /gene="RSM10"
                     /locus_tag="YDR041W"
                     /db_xref="GeneID:851611"
     mRNA            <539803..>540414
                     /gene="RSM10"
                     /locus_tag="YDR041W"
                     /product="mitochondrial 37S ribosomal protein RSM10"
                     /transcript_id="NM_001180349.1"
                     /db_xref="GI:296143397"
                     /db_xref="GeneID:851611"
     CDS             539803..540414
                     /gene="RSM10"
                     /locus_tag="YDR041W"
                     /note="Mitochondrial ribosomal protein of the small
                     subunit; has similarity to E. coli S10 ribosomal protein;
                     essential for viability, unlike most other mitoribosomal
                     proteins"
                     /codon_start=1
                     /product="mitochondrial 37S ribosomal protein RSM10"
                     /protein_id="NP_010326.1"
                     /db_xref="GI:6320246"
                     /db_xref="SGD:S000002448"
                     /db_xref="GeneID:851611"
                     /translation="MLRNTIALRSFIRTQSTRPYPVNVEAVYYAPLKLPIKYGDLVAD
                     IQLRSYDNENLDFYSDFILRTGYYLGIPLTGPKPLPTRRERWTVIKSPFVHAKSKENF
                     ERHTHKRLIRAWDTNPEVLQMLIAYITKHSMAGVGMKCNFFQRSEISLDLGSDANGLE
                     KSLSNIDELYSLRNDDKAQTSAVGQKVLELLDSPDFKKHLEKK"
     gene            complement(<540601..>541203)
                     /locus_tag="YDR042C"
                     /db_xref="GeneID:851612"
     mRNA            complement(<540601..>541203)
                     /locus_tag="YDR042C"
                     /product="hypothetical protein"
                     /transcript_id="NM_001180350.3"
                     /db_xref="GI:398365226"
                     /db_xref="GeneID:851612"
     CDS             complement(540601..541203)
                     /locus_tag="YDR042C"
                     /note="hypothetical protein; expression is increased in
                     ssu72-ts69 mutant"
                     /codon_start=1
                     /product="hypothetical protein"
                     /protein_id="NP_010327.3"
                     /db_xref="GI:398365227"
                     /db_xref="SGD:S000002449"
                     /db_xref="GeneID:851612"
                     /translation="MEQILYNQSLKISTLSTFQGLKFLKVLIFSIFQQLFYNPVIQLF
                     GTKASIMESDSTTLLESSWSTERNFLNMNSDSISATKNVFILFFTIFRLAEYIVYKLS
                     DQKYRLHTSLNVQHFRWNSKKNTNRKRTLSFSKAYLPRTNILPIFVADGLKNRFSGPL
                     PGKSLESFQKLNLLSDNNIKRYAVPGNKAVNTLLWQEQYS"
     gene            complement(541602..541700)
                     /locus_tag="snR47"
                     /db_xref="GeneID:9164877"
     ncRNA           complement(541602..541700)
                     /locus_tag="snR47"
                     /ncRNA_class="snoRNA"
                     /product="SNR47"
                     /note="C/D box small nucleolar RNA (snoRNA); guides
                     2'-O-methylation of large subunit (LSU) rRNA at position
                     A2220 and small subunit (SSU) rRNA at position A619"
                     /db_xref="SGD:S000006507"
                     /db_xref="GeneID:9164877"
     gene            complement(<542674..>543369)
                     /gene="NRG1"
                     /locus_tag="YDR043C"
                     /db_xref="GeneID:851613"
     mRNA            complement(<542674..>543369)
                     /gene="NRG1"
                     /locus_tag="YDR043C"
                     /product="Nrg1p"
                     /transcript_id="NM_001180351.3"
                     /db_xref="GI:398365236"
                     /db_xref="GeneID:851613"
     CDS             complement(542674..543369)
                     /gene="NRG1"
                     /locus_tag="YDR043C"
                     /note="Transcriptional repressor; recruits the Cyc8p-Tup1p
                     complex to promoters; mediates glucose repression and
                     negatively regulates a variety of processes including
                     filamentous growth and alkaline pH response; NRG1 has a
                     paralog, NRG2, that arose from the whole genome
                     duplication"
                     /codon_start=1
                     /product="Nrg1p"
                     /protein_id="NP_010328.3"
                     /db_xref="GI:398365237"
                     /db_xref="SGD:S000002450"
                     /db_xref="GeneID:851613"
                     /translation="MFYPYNYSNLNVSTMPALPGISAFDGMQDEENVEISPERKYQTL
                     LPVLTNSHVVENELKHKLNKTAFDFRYQTKSENGSEKWEPKYLITPNLQTRSVSFDNS
                     SVQYNSDSSEKSSLSQLTCNSSIIQQPENGIVSNDAYNKMANSRYSLKTRKQRTDPRN
                     TLSDEEDLEQRRKYICKICARGFTTSGHLARHNRIHTGEKNHCCPYKGCTQRFSRHDN
                     CLQHYRTHLKKGQ"
     gene            <546642..>547628
                     /gene="HEM13"
                     /locus_tag="YDR044W"
                     /db_xref="GeneID:851614"
     mRNA            <546642..>547628
                     /gene="HEM13"
                     /locus_tag="YDR044W"
                     /product="coproporphyrinogen oxidase"
                     /transcript_id="NM_001180352.1"
                     /db_xref="GI:296143400"
                     /db_xref="GeneID:851614"
     CDS             546642..547628
                     /gene="HEM13"
                     /locus_tag="YDR044W"
                     /EC_number="1.3.3.3"
                     /note="Coproporphyrinogen III oxidase; an oxygen requiring
                     enzyme that catalyzes the sixth step in the heme
                     biosynthetic pathway; transcription is repressed by oxygen
                     and heme (via Rox1p and Hap1p)"
                     /codon_start=1
                     /product="coproporphyrinogen oxidase"
                     /protein_id="NP_010329.1"
                     /db_xref="GI:6320249"
                     /db_xref="SGD:S000002451"
                     /db_xref="GeneID:851614"
                     /translation="MPAPQDPRNLPIRQQMEALIRRKQAEITQGLESIDTVKFHADTW
                     TRGNDGGGGTSMVIQDGTTFEKGGVNVSVVYGQLSPAAVSAMKADHKNLRLPEDPKTG
                     LPVTDGVKFFACGLSMVIHPVNPHAPTTHLNYRYFETWNQDGTPQTWWFGGGADLTPS
                     YLYEEDGQLFHQLHKDALDKHDTALYPRFKKWCDEYFYITHRKETRGIGGIFFDDYDE
                     RDPQEILKMVEDCFDAFLPSYLTIVKRRKDMPYTKEEQQWQAIRRGRYVEFNLIYDRG
                     TQFGLRTPGSRVESILMSLPEHASWLYNHHPAPGSREAKLLEVTTKPREWVK"
     gene            complement(<547978..>548310)
                     /gene="RPC11"
                     /locus_tag="YDR045C"
                     /db_xref="GeneID:851615"
     mRNA            complement(<547978..>548310)
                     /gene="RPC11"
                     /locus_tag="YDR045C"
                     /product="DNA-directed RNA polymerase III core subunit
                     RPC11"
                     /transcript_id="NM_001180353.1"
                     /db_xref="GI:296143401"
                     /db_xref="GeneID:851615"
     CDS             complement(547978..548310)
                     /gene="RPC11"
                     /locus_tag="YDR045C"
                     /note="RNA polymerase III subunit C11; mediates pol III
                     RNA cleavage activity and is important for termination of
                     transcription; homologous to TFIIS"
                     /codon_start=1
                     /product="DNA-directed RNA polymerase III core subunit
                     RPC11"
                     /protein_id="NP_010330.1"
                     /db_xref="GI:6320250"
                     /db_xref="SGD:S000002452"
                     /db_xref="GeneID:851615"
                     /translation="MLSFCPSCNNMLLITSGDSGVYTLACRSCPYEFPIEGIEIYDRK
                     KLPRKEVDDVLGGGWDNVDQTKTQCPNYDTCGGESAYFFQLQIRSADEPMTTFYKCVN
                     CGHRWKEN"
     gene            complement(<548762..>550576)
                     /gene="BAP3"
                     /locus_tag="YDR046C"
                     /gene_synonym="PAP1"
                     /db_xref="GeneID:851616"
     mRNA            complement(<548762..>550576)
                     /gene="BAP3"
                     /locus_tag="YDR046C"
                     /gene_synonym="PAP1"
                     /product="amino acid transporter BAP3"
                     /transcript_id="NM_001180354.3"
                     /db_xref="GI:398365248"
                     /db_xref="GeneID:851616"
     CDS             complement(548762..550576)
                     /gene="BAP3"
                     /locus_tag="YDR046C"
                     /gene_synonym="PAP1"
                     /note="Amino acid permease; involved in uptake of
                     cysteine, leucine, isoleucine and valine; BAP3 has a
                     paralog, BAP2, that arose from the whole genome
                     duplication"
                     /codon_start=1
                     /product="amino acid transporter BAP3"
                     /protein_id="NP_010331.3"
                     /db_xref="GI:398365249"
                     /db_xref="SGD:S000002453"
                     /db_xref="GeneID:851616"
                     /translation="MSDPIVTSSKMEKSAEFEVTDSALYNNFNTSTTASLTPEIKEHS
                     EESRNGLVHRFVDSFRRAESQRLEEDNDLEDGTKSMKSNNHLKKSMKSRHVVMMSLGT
                     GIGTGLLVANAKGLSLAGPGSLVIGYVMVSFVTYFMVQAAGEMGVTYPTLPGNFNAYN
                     SIFISKSFGFATTWLFCIQWLTVLPLELITSSMTVKYWNDTINADVFIVIFYVFLLFI
                     HFFGVKAYGETEFIFNSCKILMVAGFIILSVVINCGGAGVDGYIGGKYWRDPGSFAEG
                     SGATRFKGICYILVSAYFSFGGIELFVLSINEQSNPRKSTPVAAKRSVYRILIIYLLT
                     MILIGFNVPHNNDQLMGSGGSATHASPYVLAASIHKVRVIPHIINAVILISVISVANS
                     ALYAAPRLMCSLAQQGYAPKFLNYIDREGRPLRALVVCSLVGVVGFVACSPQEEQAFT
                     WLAAIAGLSELFTWSGIMLSHIRFRKAMKVQGRSLDEVGYKANTGIWGSYYGVFFNML
                     VFMAQFWVALSPIGNGGKCDAQAFFESYLAAPLWIFMYVGYMVYKRDFTFLNPLDKID
                     LDFHRRVYDPEIMRQEDEENKERLKNSSIFVRVYKFWC"
     gene            <551860..>552948
                     /gene="HEM12"
                     /locus_tag="YDR047W"
                     /gene_synonym="HEM6"
                     /db_xref="GeneID:851617"
     mRNA            <551860..>552948
                     /gene="HEM12"
                     /locus_tag="YDR047W"
                     /gene_synonym="HEM6"
                     /product="uroporphyrinogen decarboxylase HEM12"
                     /transcript_id="NM_001180355.3"
                     /db_xref="GI:398365256"
                     /db_xref="GeneID:851617"
     CDS             551860..552948
                     /gene="HEM12"
                     /locus_tag="YDR047W"
                     /gene_synonym="HEM6"
                     /EC_number="4.1.1.37"
                     /note="Uroporphyrinogen decarboxylase; catalyzes the fifth
                     step in the heme biosynthetic pathway; localizes to both
                     the cytoplasm and nucleus; a hem12 mutant has phenotypes
                     similar to patients with porphyria cutanea tarda"
                     /codon_start=1
                     /product="uroporphyrinogen decarboxylase HEM12"
                     /protein_id="NP_010332.3"
                     /db_xref="GI:398365257"
                     /db_xref="SGD:S000002454"
                     /db_xref="GeneID:851617"
                     /translation="MGNFPAPKNDLILRAAKGEKVERPPCWIMRQAGRYLPEYHEVKN
                     NRDFFQTCRDAEIASEITIQPVRRYRGLIDAAIIFSDILVIPQAMGMRVEMLEGKGPH
                     FPEPLRNPEDLQTVLDYKVDVLKELDWAFKAITMTRIKLDGEVPLFGFCGGPWTLMVY
                     MTEGGGSRLFRFAKQWINMYPELSHKLLQKITDVAVEFLSQQVVAGAQILQVFESWGG
                     ELSSVDFDEFSLPYLRQIAERVPKRLQELGIMEQIPMIVFAKGSWYALDKLCCSGFDV
                     VSLDWSWDPREAVKINKNRVTLQGNLDPGVMYGSKEVITKKVKQMIEAFGGGKSRYIV
                     NFGHGTHPFMDPDVIKFFLEECHRIGSK"
     gene            <553254..>555152
                     /gene="VMS1"
                     /locus_tag="YDR049W"
                     /db_xref="GeneID:851618"
     mRNA            <553254..>555152
                     /gene="VMS1"
                     /locus_tag="YDR049W"
                     /product="Vms1p"
                     /transcript_id="NM_001180357.1"
                     /db_xref="GI:296143404"
                     /db_xref="GeneID:851618"
     CDS             553254..555152
                     /gene="VMS1"
                     /locus_tag="YDR049W"
                     /note="Component of a Cdc48p-complex involved in protein
                     quality control; exhibits cytosolic and ER-membrane
                     localization, with Cdc48p, during normal growth, and
                     contributes to ER-associated degradation (ERAD) of
                     specific substrates at a step after their ubiquitination;
                     forms a mitochondrially-associated complex with Cdc48p and
                     Npl4p under oxidative stress that is required for
                     ubiquitin-mediated mitochondria-associated protein
                     degradation (MAD); conserved in C. elegans and humans"
                     /codon_start=1
                     /product="Vms1p"
                     /protein_id="NP_010334.1"
                     /db_xref="GI:6320253"
                     /db_xref="SGD:S000002456"
                     /db_xref="GeneID:851618"
                     /translation="MNSQKASKMTGSLKKNDLYIFDLSEQLLNSLKLMSFDSTLREVE
                     VEKTSDNDRNKESGDLQIARKKVTSNVMRCSVCQMSFDSRNEQKAHYQTDYHLMNVKR
                     NLRGLDILSVEEFDALISKEHGIKSEDENSGGEQTSSDHEESEEASDRDPDLQTNNYM
                     ETIIENDLQKLGFQKDESDAISHINTQSPYIYFKSKYLQKNEVLAIYKSLFNKRSLSN
                     PNEALTFWNSQENPMAISALFMVGGGHFAGAIVSHQRLNVKGNAHKKDETLIEQAVNF
                     LEHKTFHRYTTRRKQGGSQSAMDNAKGKANSAGSALRRYNESALKTDIQGVLKDWEPY
                     LSKCDNIFIRARNVSDKKIFTDNTVLNKGDERIKSFPFTTNRPTVLELKKAWCELSYL
                     KILPKPEPLAVKETVQKLEVSNKKDEFKEKQEPLLEEIQTEEIISLLKKGRAPLLISF
                     LKKNKLDGNFRLKPESKYSLTPTMLHYASQQGMKQMALILLSNIKCDPTIKNRLGRTA
                     WDLNRNDDVRHAFQIARYNLGESFTNWDETHIGQPLSREQVDEINEKKKAIENEKAEK
                     LIKLELEAAKEKQRFAKDAERGPGKKLTNIPSIQQQNLNSLTDEQRRRLMREQRARAA
                     EERMKKKY"
     STS             554268..554494
                     /gene="VMS1"
                     /locus_tag="YDR049W"
                     /standard_name="px-6e8"
                     /db_xref="UniSTS:258142"
     rep_origin      555230..555466
                     /note="ARS418;
                     Autonomously Replicating Sequence"
                     /db_xref="SGD:S000118435"
     gene            complement(<555726..>556472)
                     /gene="TPI1"
                     /locus_tag="YDR050C"
                     /db_xref="GeneID:851620"
     mRNA            complement(<555726..>556472)
                     /gene="TPI1"
                     /locus_tag="YDR050C"
                     /product="triose-phosphate isomerase TPI1"
                     /transcript_id="NM_001180358.1"
                     /db_xref="GI:296143405"
                     /db_xref="GeneID:851620"
     CDS             complement(555726..556472)
                     /gene="TPI1"
                     /locus_tag="YDR050C"
                     /EC_number="5.3.1.1"
                     /note="Triose phosphate isomerase, abundant glycolytic
                     enzyme; mRNA half-life is regulated by iron availability;
                     transcription is controlled by activators Reb1p, Gcr1p,
                     and Rap1p through binding sites in the 5' non-coding
                     region; inhibition of Tpi1p activity by PEP
                     (phosphoenolpyruvate) stimulates redox metabolism in
                     respiring cells; E104D mutation in human TPI causes a rare
                     autosomal disease"
                     /codon_start=1
                     /product="triose-phosphate isomerase TPI1"
                     /protein_id="NP_010335.1"
                     /db_xref="GI:6320255"
                     /db_xref="SGD:S000002457"
                     /db_xref="GeneID:851620"
                     /translation="MARTFFVGGNFKLNGSKQSIKEIVERLNTASIPENVEVVICPPA
                     TYLDYSVSLVKKPQVTVGAQNAYLKASGAFTGENSVDQIKDVGAKWVILGHSERRSYF
                     HEDDKFIADKTKFALGQGVGVILCIGETLEEKKAGKTLDVVERQLNAVLEEVKDWTNV
                     VVAYEPVWAIGTGLAATPEDAQDIHASIRKFLASKLGDKAASELRILYGGSANGSNAV
                     TFKDKADVDGFLVGGASLKPEFVDIINSRN"
     gene            complement(<557056..>558060)
                     /gene="DET1"
                     /locus_tag="YDR051C"
                     /db_xref="GeneID:851621"
     mRNA            complement(<557056..>558060)
                     /gene="DET1"
                     /locus_tag="YDR051C"
                     /product="Det1p"
                     /transcript_id="NM_001180359.3"
                     /db_xref="GI:398365272"
                     /db_xref="GeneID:851621"
     CDS             complement(557056..558060)
                     /gene="DET1"
                     /locus_tag="YDR051C"
                     /EC_number="3.1.3.-"
                     /note="Acid phosphatase; involved in the non-vesicular
                     transport of sterols in both directions between the
                     endoplasmic reticulum and plasma membrane; deletion
                     confers sensitivity to nickel"
                     /codon_start=1
                     /product="Det1p"
                     /protein_id="NP_010336.3"
                     /db_xref="GI:398365273"
                     /db_xref="SGD:S000002458"
                     /db_xref="GeneID:851621"
                     /translation="MCEENVHVSEDVAGSHGSFTNARPRLIVLIRHGESESNKNKEVN
                     GYIPNHLISLTKTGQIQARQAGIDLLRVLNVDDHNLVEDLAKKYIKDESSRRTLPLKD
                     YTRLSREKDTNIVFYTSPYRRARETLKGILDVIDEYNELNSGVRICEDMRYDPHGKQK
                     HAFWPRGLNNTGGVYENNEDNICEGKPGKCYLQYRVKDEPRIREQDFGNFQKINSMQD
                     VMKKRSTYGHFFFRFPHGESAADVYDRVASFQETLFRHFHDRQERRPRDVVVLVTHGI
                     YSRVFLMKWFRWTYEEFESFTNVPNGSVMVMELDESINRYVLRTVLPKWTDCEGDLTT
                     "
     gene            complement(<558511..>560625)
                     /gene="DBF4"
                     /locus_tag="YDR052C"
                     /gene_synonym="DNA52; LSD7"
                     /db_xref="GeneID:851623"
     mRNA            complement(<558511..>560625)
                     /gene="DBF4"
                     /locus_tag="YDR052C"
                     /gene_synonym="DNA52; LSD7"
                     /product="Dbf4p"
                     /transcript_id="NM_001180360.3"
                     /db_xref="GI:398365276"
                     /db_xref="GeneID:851623"
     CDS             complement(558511..560625)
                     /gene="DBF4"
                     /locus_tag="YDR052C"
                     /gene_synonym="DNA52; LSD7"
                     /note="Regulatory subunit of Cdc7p-Dbf4p kinase complex;
                     required for Cdc7p kinase activity and initiation of DNA
                     replication; phosphorylates the Mcm2-7 family of proteins;
                     cell cycle regulated; relative distribution to the nucleus
                     increases upon DNA replication stress"
                     /codon_start=1
                     /product="Dbf4p"
                     /protein_id="NP_010337.3"
                     /db_xref="GI:398365277"
                     /db_xref="SGD:S000002459"
                     /db_xref="GeneID:851623"
                     /translation="MVSPTKMIIRSPLKETDTNLKHNNGIAASTTAAGHLNVFSNDNN
                     CNNNNTTESFPKKRSLERLELQQQQHLHEKKRARIERARSIEGAVQVSKGTGLKNVEP
                     RVTPKELLEWQTNWKKIMKRDSRIYFDITDDVEMNTYNKSKMDKRRDLLKRGFLTLGA
                     QITQFFDTTVTIVITRRSVENIYLLKDTDILSRAKKNYMKVWSYEKAARFLKNLDVDL
                     DHLSKTKSASLAAPTLSNLLHNEKLYGPTDRDPRTKRDDIHYFKYPHVYLYDLWQTWA
                     PIITLEWKPQELTNLDELPYPILKIGSFGRCPFIGDRNYDESSYKRVVKRYSRDKANK
                     KYALQLRALFQYHADTLLNTSSVNDQTKNLIFIPHTCNDSTKSFKKWMQEKAKNFEKT
                     ELKKTDDSAVQDVRNEHADQTDEKNSILLNETETKEPPLKEEKENKQSIAEESNKYPQ
                     RKELAATPKLNHPVLATFARQETEEVPDDLCTLKTKSRQAFEIKASGAHQSNDVATSF
                     GNGLGPTRASVMSKNMKSLSRLMVDRKLGVKQTNGNNKNYTATIATTAETSKENRHRL
                     DFNALKKDEAPSKETGKDSAVHLETNRKPQNFPKVATKSVSADSKVHNDIKITTTESP
                     TASKKSTSTNVTLHFNAQTAQTAQPVKKETVKNSGYCENCRVKYESLEQHIVSEKHLS
                     FAENDLNFEAIDSLIENLRFQI"
     gene            complement(<561440..>562327)
                     /gene="CDC34"
                     /locus_tag="YDR054C"
                     /gene_synonym="DNA6; UBC3"
                     /db_xref="GeneID:851624"
     mRNA            complement(<561440..>562327)
                     /gene="CDC34"
                     /locus_tag="YDR054C"
                     /gene_synonym="DNA6; UBC3"
                     /product="SCF E2 ubiquitin-protein ligase catalytic
                     subunit CDC34"
                     /transcript_id="NM_001180362.1"
                     /db_xref="GI:296143408"
                     /db_xref="GeneID:851624"
     CDS             complement(561440..562327)
                     /gene="CDC34"
                     /locus_tag="YDR054C"
                     /gene_synonym="DNA6; UBC3"
                     /EC_number="6.3.2.19"
                     /note="Ubiquitin-conjugating enzyme (E2); catalytic
                     subunit of SCF ubiquitin-protein ligase complex (together
                     with Skp1p, Rbx1p, Cdc53p, and an F-box protein) that
                     regulates cell cycle progression by targeting key
                     substrates for degradation; protein abundance increases in
                     response to DNA replication stress"
                     /codon_start=1
                     /product="SCF E2 ubiquitin-protein ligase catalytic
                     subunit CDC34"
                     /protein_id="NP_010339.1"
                     /db_xref="GI:6320259"
                     /db_xref="SGD:S000002461"
                     /db_xref="GeneID:851624"
                     /translation="MSSRKSTASSLLLRQYRELTDPKKAIPSFHIELEDDSNIFTWNI
                     GVMVLNEDSIYHGGFFKAQMRFPEDFPFSPPQFRFTPAIYHPNVYRDGRLCISILHQS
                     GDPMTDEPDAETWSPVQTVESVLISIVSLLEDPNINSPANVDAAVDYRKNPEQYKQRV
                     KMEVERSKQDIPKGFIMPTSESAYISQSKLDEPESNKDMADNFWYDSDLDDDENGSVI
                     LQDDDYDDGNNHIPFEDDDVYNYNDNDDDDERIEFEDDDDDDDDSIDNDSVMDRKQPH
                     KAEDESEDVEDVERVSKKI"
     gene            <563527..>564861
                     /gene="PST1"
                     /locus_tag="YDR055W"
                     /gene_synonym="HPF2"
                     /db_xref="GeneID:851625"
     mRNA            <563527..>564861
                     /gene="PST1"
                     /locus_tag="YDR055W"
                     /gene_synonym="HPF2"
                     /product="Pst1p"
                     /transcript_id="NM_001180363.1"
                     /db_xref="GI:296143409"
                     /db_xref="GeneID:851625"
     CDS             563527..564861
                     /gene="PST1"
                     /locus_tag="YDR055W"
                     /gene_synonym="HPF2"
                     /note="Cell wall protein that contains a putative
                     GPI-attachment site; secreted by regenerating protoplasts;
                     up-regulated by activation of the cell integrity pathway,
                     as mediated by Rlm1p; upregulated by cell wall damage via
                     disruption of FKS1; PST1 has a paralog, ECM33, that arose
                     from the whole genome duplication"
                     /codon_start=1
                     /product="Pst1p"
                     /protein_id="NP_010340.1"
                     /db_xref="GI:6320260"
                     /db_xref="SGD:S000002462"
                     /db_xref="GeneID:851625"
                     /translation="MQLHSLIASTALLITSALAATSSSSSIPSSCTISSHATATAQSD
                     LDKYSRCDTLVGNLTIGGGLKTGALANVKEINGSLTIFNATNLTSFAADSLESITDSL
                     NLQSLTILTSASFGSLQSVDSIKLITLPAISSFTSNIKSANNIYISDTSLQSVDGFSA
                     LKKVNVFNVNNNKKLTSIKSPVETVSDSLQFSFNGNQTKITFDDLVWANNISLTDVHS
                     VSFANLQKINSSLGFINNSISSLNFTKLNTIGQTFSIVSNDYLKNLSFSNLSTIGGAL
                     VVANNTGLQKIGGLDNLTTIGGTLEVVGNFTSLNLDSLKSVKGGADVESKSSNFSCNA
                     LKALQKKGGIKGESFVCKNGASSTSVKLSSTSKSQSSQTTAKVSKSSSKAEEKKFTSG
                     DIKAAASASSVSSSGASSSSSKSSKGNAAIMAPIGQTTPLVGLLTAIIMSIM"
     gene            complement(<565023..>565640)
                     /locus_tag="YDR056C"
                     /db_xref="GeneID:851626"
     mRNA            complement(<565023..>565640)
                     /locus_tag="YDR056C"
                     /product="hypothetical protein"
                     /transcript_id="NM_001180364.3"
                     /db_xref="GI:398365294"
                     /db_xref="GeneID:851626"
     CDS             complement(565023..565640)
                     /locus_tag="YDR056C"
                     /note="hypothetical protein; green fluorescent protein
                     (GFP)-fusion protein localizes to the endoplasmic
                     reticulum; YDR056C is not an essential protein"
                     /codon_start=1
                     /product="hypothetical protein"
                     /protein_id="NP_010341.3"
                     /db_xref="GI:398365295"
                     /db_xref="SGD:S000002463"
                     /db_xref="GeneID:851626"
                     /translation="MLVRLLRVILLASMVFCADILQLSYSDDAKDAIPLGTFEIDSTS
                     DGNVTVTTVNIQDVEVSGEYCLNAQIEGKLDMPCFSYMKLRTPLKYDLIVDVDEDNEV
                     KQVSLSYDETNDAITATVRYPEAGPTAPVTKLKKKTKTYADKKASKNKDGSTAQFEED
                     EEVKEVSWFQKNWKMLLLGLLIYNFVAGSAKKQQQGGAGADQKTE"
     gene            <565927..>567555
                     /gene="YOS9"
                     /locus_tag="YDR057W"
                     /db_xref="GeneID:851627"
     mRNA            <565927..>567555
                     /gene="YOS9"
                     /locus_tag="YDR057W"
                     /product="Yos9p"
                     /transcript_id="NM_001180365.3"
                     /db_xref="GI:398365296"
                     /db_xref="GeneID:851627"
     CDS             565927..567555
                     /gene="YOS9"
                     /locus_tag="YDR057W"
                     /note="ER quality-control lectin; integral subunit of the
                     HRD ligase; participates in efficient ER retention of
                     misfolded proteins by recognizing them and delivering them
                     to Hrd1p; binds to glycans with terminal alpha-1,6 linked
                     mannose on misfolded N-glycosylated proteins and
                     participates in targeting proteins to ERAD; member of the
                     OS-9 protein family"
                     /codon_start=1
                     /product="Yos9p"
                     /protein_id="NP_010342.3"
                     /db_xref="GI:398365297"
                     /db_xref="SGD:S000002464"
                     /db_xref="GeneID:851627"
                     /translation="MQAKIIYALSAISALIPLGSSLLAPIEDPIVSNKYLISYIDEDD
                     WSDRILQNQSVMNSGYIVNMGDDLECFIQNASTQLNDVLEDSNEHSNSEKTALLTKTL
                     NQGVKTIFDKLNERCIFYQAGFWIYEYCPGIEFVQFHGRVNTKTGEIVNRDESLVYRL
                     GKPKANVEEREFELLYDDVGYYISEIIGSGDICDVTGAERMVEIQYVCGGSNSGPSTI
                     QWVRETKICVYEAQVTIPELCNLELLAKNEDQKNASPILCRMPAKSKIGSNSIDLITK
                     YEPIFLGSGIYFLRPFNTDERDKLMVTDNAMSNWDEITETYYQKFGNAINKMLSLRLV
                     SLPNGHILQPGDSCVWLAEVVDMKDRFQTTLSLNILNSQRAEIFFNKTFTFNEDNGNF
                     LSYKIGDHGESTELGQITHSNKADINTAEIRSDEYLINTDNELFLRISKEIAEVKELL
                     NEIVSPHEMEVIFENMRNQPNNDFELALMNKLKSSLNDDNKVEQINNARMDDDESTSH
                     TTRDIGEAGSQTTGNTESEVTNVAAGVFIEHDEL"
     rep_origin      567496..567742
                     /note="ARS419;
                     Autonomously Replicating Sequence"
                     /db_xref="SGD:S000118436"
     gene            complement(<567723..>568703)
                     /gene="TGL2"
                     /locus_tag="YDR058C"
                     /db_xref="GeneID:851628"
     mRNA            complement(<567723..>568703)
                     /gene="TGL2"
                     /locus_tag="YDR058C"
                     /product="Tgl2p"
                     /transcript_id="NM_001180366.1"
                     /db_xref="GI:296143412"
                     /db_xref="GeneID:851628"
     CDS             complement(567723..568703)
                     /gene="TGL2"
                     /locus_tag="YDR058C"
                     /EC_number="3.1.1.3"
                     /note="Triacylglycerol lipase that is localized to the
                     mitochondria; has lipolytic activity towards
                     triacylglycerols and diacylglycerols when expressed in E.
                     coli"
                     /codon_start=1
                     /product="Tgl2p"
                     /protein_id="NP_010343.1"
                     /db_xref="GI:6320263"
                     /db_xref="SGD:S000002465"
                     /db_xref="GeneID:851628"
                     /translation="MKNDNKANDIIIDSVKVPDSYKPPKNPIVFCHGLSGFDKLILIP
                     SVFHLTNLISNSIVHNMAENFMQDDEDKSDNKYTNLLEIEYWIGVKKFLQSKGCTVIT
                     TKVPGFGSIEERAMALDAQLQKEVKKIESKDKRHSLNLIAHSMGGLDCRYLICNIKNR
                     NYDILSLTTISTPHRGSEMADYVVDLFENLNALRVSQKILPICFYQLTTAYMKYFNLV
                     TPNSPKVSYFSYGCSFVPKWYNVFCTPWKIVYERSKGCPNDGLVTINSSKWGEYRGTL
                     KDMDHLDVINWKNKLQDDWSKFFRTTTVGEKVDILNFYLKITDDLARKGF"
     gene            568882..568953
                     /locus_tag="tR(UCU)D"
                     /db_xref="GeneID:851629"
     tRNA            568882..568953
                     /locus_tag="tR(UCU)D"
                     /product="tRNA-Arg"
                     /note="Arginine tRNA (tRNA-Arg), predicted by tRNAscan-SE
                     analysis; one of 11 nuclear tRNA genes containing the
                     tDNA-anticodon UCU (converted to mcm5-UCU in the mature
                     tRNA), decodes AGA codons into arginine, one of 19 nuclear
                     tRNAs for arginine"
                     /db_xref="SGD:S000006709"
                     /db_xref="GeneID:851629"
     gene            568964..569035
                     /locus_tag="tD(GUC)D"
                     /db_xref="GeneID:851630"
     tRNA            568964..569035
                     /locus_tag="tD(GUC)D"
                     /product="tRNA-Asp"
                     /note="Aspartate tRNA (tRNA-Asp), predicted by tRNAscan-SE
                     analysis"
                     /db_xref="SGD:S000006531"
                     /db_xref="GeneID:851630"
     gene            complement(<569234..>569770)
                     /gene="UBC5"
                     /locus_tag="YDR059C"
                     /db_xref="GeneID:851631"
     mRNA            complement(join(<569234..569633,569724..>569770))
                     /gene="UBC5"
                     /locus_tag="YDR059C"
                     /product="E2 ubiquitin-conjugating protein UBC5"
                     /transcript_id="NM_001180367.1"
                     /db_xref="GI:296143413"
                     /db_xref="GeneID:851631"
     CDS             complement(join(569234..569633,569724..569770))
                     /gene="UBC5"
                     /locus_tag="YDR059C"
                     /EC_number="6.3.2.19"
                     /note="Ubiquitin-conjugating enzyme; mediates selective
                     degradation of short-lived, abnormal, or excess proteins,
                     including histone H3; central component of the cellular
                     stress response; expression is heat inducible; protein
                     abundance increases in response to DNA replication stress;
                     UBC5 has a paralog, UBC4, that arose from the whole genome
                     duplication"
                     /codon_start=1
                     /product="E2 ubiquitin-conjugating protein UBC5"
                     /protein_id="NP_010344.1"
                     /db_xref="GI:6320264"
                     /db_xref="SGD:S000002466"
                     /db_xref="GeneID:851631"
                     /translation="MSSSKRIAKELSDLGRDPPASCSAGPVGDDLYHWQASIMGPSDS
                     PYAGGVFFLSIHFPTDYPFKPPKVNFTTKIYHPNINSSGNICLDILKDQWSPALTLSK
                     VLLSICSLLTDANPDDPLVPEIAQIYKTDKAKYEATAKEWTKKYAV"
     gene            <570649..>573726
                     /gene="MAK21"
                     /locus_tag="YDR060W"
                     /gene_synonym="NOC1"
                     /db_xref="GeneID:851632"
     mRNA            <570649..>573726
                     /gene="MAK21"
                     /locus_tag="YDR060W"
                     /gene_synonym="NOC1"
                     /product="Mak21p"
                     /transcript_id="NM_001180368.3"
                     /db_xref="GI:398365318"
                     /db_xref="GeneID:851632"
     CDS             570649..573726
                     /gene="MAK21"
                     /locus_tag="YDR060W"
                     /gene_synonym="NOC1"
                     /note="Constituent of 66S pre-ribosomal particles;
                     required for large (60S) ribosomal subunit biogenesis;
                     acts as part of a Mak21p-Noc2p-Rrp5p module that
                     associates with nascent pre-rRNA during transcription and
                     has a role in bigenesis of the large ribosomal subunit;
                     involved in nuclear export of pre-ribosomes; required for
                     maintenance of dsRNA virus; homolog of human CAATT-binding
                     protein"
                     /codon_start=1
                     /product="Mak21p"
                     /protein_id="NP_010345.3"
                     /db_xref="GI:398365319"
                     /db_xref="SGD:S000002467"
                     /db_xref="GeneID:851632"
                     /translation="MSENNGNPLDLSSLRNKISSKLRDNNSKKAKKTHKGKDVKASSN
                     SKKVNEDIRREALALGASEEDLKLIQGLSDDDDAKSEQEFDAVADEDADDKGFKNDLQ
                     NFMKNVGFDQHKLEDVDDDDIEEESTSSKESKIPAQEKEHAQSNIASSTIEKTSQESI
                     DNGSEQEENTVEEANLSSDQEPESESAEKEKKEEKDGGLITQTTIISSDKLIIPYDKP
                     WYEIPLDPQVGQNDDVEELSKEQIEKLFERGKQTLEADNQTYYEEFTKDSSQAKFMSQ
                     ILSDGTLNDKISAVTLLIQDSPLHNTKSLETLVSYCGKKSRNSALQSLNALKDLFLNG
                     LLPNRKLRYFKNQPGLSMMLNKKTLAIFYFEDYLKKLFFRVLEVLEVLSHDPIIHVRL
                     QILNHVFDLLTNQPEQEFNLLRLGVNKIGDIDSKVSSKASYLLLKLEQAHPNMKSIVI
                     DAIVDIALRPNADYHTTYYSVITLNQTILKRSEDSVANKLVKTYFTLFEKFLINTDKD
                     NTNGVVKSNSKSYEEKRKKNFKKGKHGGKSVKIEKTENEVLDEKNSKLFSALLTGINR
                     AFPFAQIPASVYEVHMETLFKITHSSNFNTSIQALVLINQVTVKAKLNSDRYYRTLYE
                     SLFDPRLVNSSKQGIYLNLLYKSLKQDALNVERVEAFVKRILQVCSHWLNVGTITGFF
                     FLLIQLAKTVPQIKNLLTNTPVDYEYESDAEEEQGDKDIKRKEYDGRKRDPKFANAEK
                     SSLWEINNFINHFHPTVKTYANAYVTGETEQIAKPDLGLFTLSHFLDRFVYRSAKQTN
                     TARGTSIMQPLFSGSRVNDSVLVKASDIMHDQGPVNTEDWLTKKVEDIKPEDKFFYQY
                     FTTKKTADGKGKKSNKASNFDSDDEMDENEIWSALVKSRPDVEDDSDDSELDFAEDDF
                     SDSTSDDEPKLDAIDDEDAKSEGSQESDQEEGLDEDIFYSFDGEQDNSDKKRSFAESS
                     EEDESSEEEKEEEENKEVSAKRAKKKQRKNMLKSLPVFASADDYAQYLDQDSD"
     gene            <574164..>575783
                     /locus_tag="YDR061W"
                     /db_xref="GeneID:851633"
     mRNA            <574164..>575783
                     /locus_tag="YDR061W"
                     /product="hypothetical protein"
                     /transcript_id="NM_001180369.3"
                     /db_xref="GI:398365332"
                     /db_xref="GeneID:851633"
     CDS             574164..575783
                     /locus_tag="YDR061W"
                     /note="Protein with similarity to ABC transporter family
                     members; lacks predicted membrane-spanning regions;
                     transcriptionally activated by Yrm1p along with genes
                     involved in multidrug resistance"
                     /codon_start=1
                     /product="hypothetical protein"
                     /protein_id="NP_010346.3"
                     /db_xref="GI:398365333"
                     /db_xref="SGD:S000002468"
                     /db_xref="GeneID:851633"
                     /translation="MSTNKFVVRITNALFKSSLASNSPPVYPKRIRHFEILPNEKWVI
                     WGPGKGKFLDVLNNKYICEPPLSLRFGFLKESSNILPRIEQVAFKGVMPTAHLSARYE
                     YFKDDYDQTCKQFIFDKASGSNAVSYKVETNNRQINMELYNALVENLNLSSLQDRWVM
                     GLSNGQMRRARLARSILKEPDLLLIDDPFLGLDPAAIATISQFLAKYDSIEVSGGCPI
                     VIGLRYQDTIPAWCTHICCVDEKNGILFEGPIEKLQSKMDETRSRALKELEQLKKASN
                     SKEDISINDLICIHPMYGKKEHEIIKMPHLIELDGLSVSYKGEAVLENLHWKVQPGSK
                     WHIRGDNGSGKSTLLSLLTAEHPQSWNSRVIDNGVPRRTGKTNYFDLNSKIGMSSPEL
                     HAIFLKNAGGRLNIRESVATGYHEASSNNYLPIWKRLDKNSQEIVNMYLKYFGLDKDA
                     DSVLFEQLSVSDQKLVLFVRSLIKMPQILILDEAFSGMEVEPMMRCHEFLEEWPGTVL
                     VVAHVAEETPKCAHYLRLISPGEYEIGDMEN"
     gene            <576474..>578159
                     /gene="LCB2"
                     /locus_tag="YDR062W"
                     /gene_synonym="SCS1; TSC1"
                     /db_xref="GeneID:851634"
     mRNA            <576474..>578159
                     /gene="LCB2"
                     /locus_tag="YDR062W"
                     /gene_synonym="SCS1; TSC1"
                     /product="serine C-palmitoyltransferase LCB2"
                     /transcript_id="NM_001180370.1"
                     /db_xref="GI:296143416"
                     /db_xref="GeneID:851634"
     CDS             576474..578159
                     /gene="LCB2"
                     /locus_tag="YDR062W"
                     /gene_synonym="SCS1; TSC1"
                     /EC_number="2.3.1.50"
                     /note="Component of serine palmitoyltransferase;
                     responsible along with Lcb1p for the first committed step
                     in sphingolipid synthesis, which is the condensation of
                     serine with palmitoyl-CoA to form 3-ketosphinganine"
                     /codon_start=1
                     /product="serine C-palmitoyltransferase LCB2"
                     /protein_id="NP_010347.1"
                     /db_xref="GI:6320267"
                     /db_xref="SGD:S000002469"
                     /db_xref="GeneID:851634"
                     /translation="MSTPANYTRVPLCEPEELPDDIQKENEYGTLDSPGHLYQVKSRH
                     GKPLPEPVVDTPPYYISLLTYLNYLILIILGHVHDFLGMTFQKNKHLDLLEHDGLAPW
                     FSNFESFYVRRIKMRIDDCFSRPTTGVPGRFIRCIDRISHNINEYFTYSGAVYPCMNL
                     SSYNYLGFAQSKGQCTDAALESVDKYSIQSGGPRAQIGTTDLHIKAEKLVARFIGKED
                     ALVFSMGYGTNANLFNAFLDKKCLVISDELNHTSIRTGVRLSGAAVRTFKHGDMVGLE
                     KLIREQIVLGQPKTNRPWKKILICAEGLFSMEGTLCNLPKLVELKKKYKCYLFIDEAH
                     SIGAMGPTGRGVCEIFGVDPKDVDILMGTFTKSFGAAGGYIAADQWIIDRLRLDLTTV
                     SYSESMPAPVLAQTISSLQTISGEICPGQGTERLQRIAFNSRYLRLALQRLGFIVYGV
                     ADSPVIPLLLYCPSKMPAFSRMMLQRRIAVVVVAYPATPLIESRVRFCMSASLTKEDI
                     DYLLRHVSEVGDKLNLKSNSGKSSYDGKRQRWDIEEVIRRTPEDCKDDKYFVN"
     gene            <578663..>579112
                     /gene="AIM7"
                     /locus_tag="YDR063W"
                     /gene_synonym="GMF1"
                     /db_xref="GeneID:851635"
     mRNA            <578663..>579112
                     /gene="AIM7"
                     /locus_tag="YDR063W"
                     /gene_synonym="GMF1"
                     /product="Aim7p"
                     /transcript_id="NM_001180371.1"
                     /db_xref="GI:296143417"
                     /db_xref="GeneID:851635"
     CDS             578663..579112
                     /gene="AIM7"
                     /locus_tag="YDR063W"
                     /gene_synonym="GMF1"
                     /note="Protein that interacts with Arp2/3 complex;
                     interacts with Arp2/3 complex to stimulate actin filament
                     debranching and inhibit actin nucleation; has similarity
                     to Cof1p and also to human glia maturation factor (GMF);
                     null mutant displays elevated mitochondrial genome loss"
                     /codon_start=1
                     /product="Aim7p"
                     /protein_id="NP_010348.1"
                     /db_xref="GI:6320268"
                     /db_xref="SGD:S000002470"
                     /db_xref="GeneID:851635"
                     /translation="MSNLYKIGTETRNKIKKFRTSTARTDSIKALSIKIEPKPSYEII
                     VDEDEQEELDEIEDLSELAEILPDNSPRFVLTAYPTTTKDGFKQTPLVLVYWKPMTVV
                     SQEWKMLYAGALEMIREECGTFKLIEVSSGLEDDSDVEELREQLENC"
     gene            <579458..>580452
                     /gene="RPS13"
                     /locus_tag="YDR064W"
                     /gene_synonym="RPS13B; RPS13C"
                     /db_xref="GeneID:851636"
     mRNA            join(<579458..579478,580018..>580452)
                     /gene="RPS13"
                     /locus_tag="YDR064W"
                     /gene_synonym="RPS13B; RPS13C"
                     /product="ribosomal 40S subunit protein S13"
                     /transcript_id="NM_001180372.3"
                     /db_xref="GI:398365350"
                     /db_xref="GeneID:851636"
     CDS             join(579458..579478,580018..580452)
                     /gene="RPS13"
                     /locus_tag="YDR064W"
                     /gene_synonym="RPS13B; RPS13C"
                     /note="Protein component of the small (40S) ribosomal
                     subunit; homologous to mammalian ribosomal protein S13 and
                     bacterial S15"
                     /codon_start=1
                     /product="ribosomal 40S subunit protein S13"
                     /protein_id="NP_010349.3"
                     /db_xref="GI:398365351"
                     /db_xref="SGD:S000002471"
                     /db_xref="GeneID:851636"
                     /translation="MGRMHSAGKGISSSAIPYSRNAPAWFKLSSESVIEQIVKYARKG
                     LTPSQIGVLLRDAHGVTQARVITGNKIMRILKSNGLAPEIPEDLYYLIKKAVSVRKHL
                     ERNRKDKDAKFRLILIESRIHRLARYYRTVAVLPPNWKYESATASALVN"
     gene            <580687..>581784
                     /gene="RRG1"
                     /locus_tag="YDR065W"
                     /db_xref="GeneID:851637"
     mRNA            <580687..>581784
                     /gene="RRG1"
                     /locus_tag="YDR065W"
                     /product="Rrg1p"
                     /transcript_id="NM_001180373.3"
                     /db_xref="GI:398365356"
                     /db_xref="GeneID:851637"
     CDS             580687..581784
                     /gene="RRG1"
                     /locus_tag="YDR065W"
                     /note="hypothetical protein; required for vacuolar
                     acidification and mitochondrial genome maintenance; the
                     authentic, non-tagged protein is detected in highly
                     purified mitochondria in high-throughput studies"
                     /codon_start=1
                     /product="Rrg1p"
                     /protein_id="NP_010350.3"
                     /db_xref="GI:398365357"
                     /db_xref="SGD:S000002472"
                     /db_xref="GeneID:851637"
                     /translation="MAQNFGKIPSHKSYVLSLYRTVLRNIPKCCHSYAFQYEIKKTLS
                     IQLFKHKHDKSSWSVYTLLNEFSLLNNCLLEGKLQEIKNLMKPLKKMKKQLKTTKILN
                     SLTSLGDVKTNDPEEVRRFHVLSAYIKRKQDLGLLPAYIPKTYQHKLLLPLALNEHAC
                     LKLFHIQQKLKNGPPSAGLSYTKEGRNQIWFVRSPINKGRQQSKKLGILIRKERKDSQ
                     KNIDNLNFCEINAAWALHEAIWEEYLESKKIIKVNLPKYLEYAANIPKSTKCNPSSQY
                     QKVKEWVDPVREIMFELHSKSFQRVEYFNKYKEKLLKNGGQLAYFDKKSKEMYAKRLT
                     LFRKMSKETLPYVTLFIEGRDLPSVLAKYGF"
     gene            complement(<581908..>582498)
                     /gene="RTR2"
                     /locus_tag="YDR066C"
                     /db_xref="GeneID:851638"
     mRNA            complement(<581908..>582498)
                     /gene="RTR2"
                     /locus_tag="YDR066C"
                     /product="Rtr2p"
                     /transcript_id="NM_001180374.1"
                     /db_xref="GI:296143420"
                     /db_xref="GeneID:851638"
     CDS             complement(581908..582498)
                     /gene="RTR2"
                     /locus_tag="YDR066C"
                     /EC_number="3.1.3.16"
                     /note="hypothetical protein; exhibits genetic interactions
                     with Rtr1p; green fluorescent protein (GFP)-fusion protein
                     localizes to the cytoplasm; YDR066C is not an essential
                     gene; relocalizes from nucleus to cytoplasmic foci upon
                     DNA replication stress; RTR2 has a paralog, RTR1, that
                     arose from the whole genome duplication"
                     /codon_start=1
                     /product="Rtr2p"
                     /protein_id="NP_010351.1"
                     /db_xref="GI:6320271"
                     /db_xref="SGD:S000002473"
                     /db_xref="GeneID:851638"
                     /translation="MQIITTTFIQKVILGSHQLHEQLSIVEARMIESAIVSMLTESFC
                     ENEQTLKYLARLLSPMSYMDVINARRGKKICGYPLCYKSAAENSSDGFFIHSMYCNNY
                     HSKCSLYLMRQLSQTPLHERRGVHLTSYINLEFDDMYSVSLLEELVGSEVPIDTVKSL
                     ITSFKDLEFDDTYKNEPLPLDVYFGQLTTDEETCIE"
     gene            complement(<582791..>583465)
                     /gene="OCA6"
                     /locus_tag="YDR067C"
                     /db_xref="GeneID:851639"
     mRNA            complement(<582791..>583465)
                     /gene="OCA6"
                     /locus_tag="YDR067C"
                     /product="Oca6p"
                     /transcript_id="NM_001180375.1"
                     /db_xref="GI:296143421"
                     /db_xref="GeneID:851639"
     CDS             complement(582791..583465)
                     /gene="OCA6"
                     /locus_tag="YDR067C"
                     /EC_number="3.1.3.48"
                     /note="Cytoplasmic protein required for replication of
                     Brome mosaic virus; S. cerevisiae is a model system for
                     studying positive-strand RNA virus replication; null
                     mutation confers sensitivity to tunicamycin and DTT"
                     /codon_start=1
                     /product="Oca6p"
                     /protein_id="NP_010352.1"
                     /db_xref="GI:6320272"
                     /db_xref="SGD:S000002474"
                     /db_xref="GeneID:851639"
                     /translation="MTLVTPLQFSTVQPNLYRGSYPREINLPFLRTLRLKYILSLTPE
                     PLSTDPLMVKFCEENNIKTIHIKCQSERKADKTKPKIKRKKKTVPIEYDVVVRCVKFL
                     IDKGHYPCYMHCTNGELIISLVVACMRKFSYWSTVSILNEFLVYNSSINIHERNFIEN
                     FNSEIEVDDLDIKDKVPWITVRYIARTATESKDELRVDDANASEKVARVSSVSNSLPK
                     LKFHSM"
     gene            <583713..>584645
                     /gene="DOS2"
                     /locus_tag="YDR068W"
                     /db_xref="GeneID:851640"
     mRNA            <583713..>584645
                     /gene="DOS2"
                     /locus_tag="YDR068W"
                     /product="Dos2p"
                     /transcript_id="NM_001180376.3"
                     /db_xref="GI:398365380"
                     /db_xref="GeneID:851640"
     CDS             583713..584645
                     /gene="DOS2"
                     /locus_tag="YDR068W"
                     /note="hypothetical protein; green fluorescent protein
                     (GFP)-fusion protein localizes to the cytoplasm"
                     /codon_start=1
                     /product="Dos2p"
                     /protein_id="NP_010353.3"
                     /db_xref="GI:398365381"
                     /db_xref="SGD:S000002475"
                     /db_xref="GeneID:851640"
                     /translation="MEFFYEEQVACIEDDKISNSHTKETGSTENTENNELQSRDDKTN
                     EAFQKLEEEVNKRYEKTTSAFKKLVIEKDDGIEINLPISNETTETAQKYLKKLDENIH
                     SVESLAQSYWSKMKTKNFWSGFSSFDNAAENDSNDKDENSKENEIAVGGNRTEAELRT
                     LSKDKSVYLDNKMDLQLDPFDVDEKTEEICSILQGDKDISKLMNDIVPHKISYKDFWH
                     IYFLQRNKILDKESKRKEILSKKEKETEEKEVEWDDEEEEEDDDKVEAVADNKSKGET
                     KVAVSQEGLKDVSDHVGLANKDESKDDDDDDDWE"
     gene            complement(<584939..>587719)
                     /gene="DOA4"
                     /locus_tag="YDR069C"
                     /gene_synonym="DOS1; MUT4; NPI2; SSV7; UBP4"
                     /db_xref="GeneID:851641"
     mRNA            complement(<584939..>587719)
                     /gene="DOA4"
                     /locus_tag="YDR069C"
                     /gene_synonym="DOS1; MUT4; NPI2; SSV7; UBP4"
                     /product="Doa4p"
                     /transcript_id="NM_001180377.3"
                     /db_xref="GI:398365390"
                     /db_xref="GeneID:851641"
     CDS             complement(584939..587719)
                     /gene="DOA4"
                     /locus_tag="YDR069C"
                     /gene_synonym="DOS1; MUT4; NPI2; SSV7; UBP4"
                     /EC_number="3.4.19.12"
                     /note="Ubiquitin hydrolase that deubiquitinates ILV cargo
                     proteins; required for recycling ubiquitin from
                     proteasome-bound ubiquitinated intermediates, acts at the
                     late endosome/prevacuolar compartment to recover ubiquitin
                     from ubiquitinated membrane proteins en route to the
                     vacuole; DOA4 has a paralog, UBP5, that arose from the
                     whole genome duplication"
                     /codon_start=1
                     /product="Doa4p"
                     /protein_id="NP_010354.3"
                     /db_xref="GI:398365391"
                     /db_xref="SGD:S000002476"
                     /db_xref="GeneID:851641"
                     /translation="MEQNIISTIRDECIRHRSKYLTIAQLTAIAEAKINEFIITGKAK
                     DQDLSSLLDKCIDILSIYKKNSKDIKNIISCKNKGAMISSNSVMIIQLNYVYYKVIHI
                     IVTTNIPHLSEFAKIKLHKSTSDEGNGNNNNNEFQLMNIYNTLLETLLKDENIAKIKS
                     FIKSSIKQTKLNHEQEECNLMRTGSYITSNQLNSLISSSANSASSQMEILLIDIRSRL
                     EFNKSHIDTKNIICLEPISFKMSYSDHDLEKKSLITSPNSEIKMFQSRNLFKFIILYT
                     DANEYNVKQQSVLLDILVNHSFEKPISDDFTKIFILESGFPGWLKSNYGRQVSSSFPS
                     NNNIKDDSVYINGNTSGLSLQHLPKMSPSIRHSMDDSMKEMLVAPTPLNHLQQQQQQQ
                     SDNDHVLKRSSSFKKLFSNYTSPNPKNSNSNLYSISSLSISSSPSPLPLHSPDPVKGN
                     SLPINYPETPHLWKNSETDFMTNQREQLNHNSFAHIAPINTKAITSPSRTATPKLQRF
                     PQTISMNLNMNSNGHSSATSTIQPSCLSLSNNDSLDHTDVTPTSSHNYDLDFAVGLEN
                     LGNSCYMNCIIQCILGTHELTQIFLDDSYAKHININSKLGSKGILAKYFARLVHMMYK
                     EQVDGSKKISISPIKFKLACGSVNSLFKTASQQDCQEFCQFLLDGLHEDLNQCGSNPP
                     LKELSQEAEARREKLSLRIASSIEWERFLTTDFSVIVDLFQGQYASRLKCKVCSHTST
                     TYQPFTVLSIPIPKKNSRNNITIEDCFREFTKCENLEVDEQWLCPHCEKRQPSTKQLT
                     ITRLPRNLIVHLKRFDNLLNKNNDFVIYPFLLDLTPFWANDFDGVFPPGVNDDELPIR
                     GQIPPFKYELYGVACHFGTLYGGHYTAYVKKGLKKGWLYFDDTKYKPVKNKADAINSN
                     AYVLFYHRVYGV"
     gene            complement(<588098..>588379)
                     /gene="FMP16"
                     /locus_tag="YDR070C"
                     /db_xref="GeneID:851642"
     mRNA            complement(<588098..>588379)
                     /gene="FMP16"
                     /locus_tag="YDR070C"
                     /product="Fmp16p"
                     /transcript_id="NM_001180378.1"
                     /db_xref="GI:296143424"
                     /db_xref="GeneID:851642"
     CDS             complement(588098..588379)
                     /gene="FMP16"
                     /locus_tag="YDR070C"
                     /note="hypothetical protein; may be involved in responding
                     to conditions of stress; the authentic, non-tagged protein
                     is detected in highly purified mitochondria in
                     high-throughput studies; protein abundance increases in
                     response to DNA replication stress"
                     /codon_start=1
                     /product="Fmp16p"
                     /protein_id="NP_010355.1"
                     /db_xref="GI:6320275"
                     /db_xref="SGD:S000002477"
                     /db_xref="GeneID:851642"
                     /translation="MLRTTFLRTPRQLMRKSPRASFSIVTRAAFPHLKNNQDEAEKKE
                     QGLFDSNKKRLDTLEHGKNPDYKQPGMEDLKKKGDDARIEQNRPDDGVY"
     gene            complement(<588827..>589402)
                     /gene="PAA1"
                     /locus_tag="YDR071C"
                     /db_xref="GeneID:851643"
     mRNA            complement(<588827..>589402)
                     /gene="PAA1"
                     /locus_tag="YDR071C"
                     /product="Paa1p"
                     /transcript_id="NM_001180379.1"
                     /db_xref="GI:296143425"
                     /db_xref="GeneID:851643"
     CDS             complement(588827..589402)
                     /gene="PAA1"
                     /locus_tag="YDR071C"
                     /EC_number="2.3.1.-"
                     /note="Polyamine acetyltransferase; acetylates polyamines
                     (e.g. putrescine, spermidine, spermine) and also
                     aralkylamines (e.g. tryptamine, phenylethylamine); may be
                     involved in transcription and/or DNA replication"
                     /codon_start=1
                     /product="Paa1p"
                     /protein_id="NP_010356.1"
                     /db_xref="GI:6320276"
                     /db_xref="SGD:S000002478"
                     /db_xref="GeneID:851643"
                     /translation="MASSSSTLPLHMYIRPLIIEDLKQILNLESQGFPPNERASEEII
                     SFRLINCPELCSGLFIREIEGKEVKKETLIGHIMGTKIPHEYITIESMGKLQVESSNH
                     IGIHSVVIKPEYQKKNLATLLLTDYIQKLSNQEIGNKIVLIAHEPLIPFYERVGFKII
                     AENTNVAKDKNFAEQKWIDMERELIKEEYDN"
     gene            complement(<589761..>591344)
                     /gene="IPT1"
                     /locus_tag="YDR072C"
                     /gene_synonym="KTI6; MIC2; SYR4"
                     /db_xref="GeneID:851644"
     mRNA            complement(<589761..>591344)
                     /gene="IPT1"
                     /locus_tag="YDR072C"
                     /gene_synonym="KTI6; MIC2; SYR4"
                     /product="inositolphosphotransferase"
                     /transcript_id="NM_001180380.3"
                     /db_xref="GI:398365414"
                     /db_xref="GeneID:851644"
     CDS             complement(589761..591344)
                     /gene="IPT1"
                     /locus_tag="YDR072C"
                     /gene_synonym="KTI6; MIC2; SYR4"
                     /EC_number="2.-.-.-"
                     /note="Inositolphosphotransferase; involved in synthesis
                     of mannose-(inositol-P)2-ceramide (M(IP)2C), the most
                     abundant sphingolipid; can mutate to resistance to the
                     antifungals syringomycin E and DmAMP1 and to K. lactis
                     zymocin"
                     /codon_start=1
                     /product="inositolphosphotransferase"
                     /protein_id="NP_010357.3"
                     /db_xref="GI:398365415"
                     /db_xref="SGD:S000002479"
                     /db_xref="GeneID:851644"
                     /translation="MNVIFSLASFVKNMYNASLNQRNLISLPFNFMLNFAPVFIWLSI
                     FKRAGLIPIRLRPDIHSKFAFFADQFLFGDYWHELTVQLPDNTSKLFFWSFISSSAFL
                     LVFLICIPFAIWYYIYYIKHVNYNLLEWFANIFHYPCKRKQRPIQKRFRTIFIPFALP
                     LFTFVILNIDHFFAYQSDANFTKTKDLLAWFSYVILHLTAPILTAVYLYVFQPPGTLK
                     CFSFALGLQNIAGVLTHLLVPMASPWFTHLYGIDDTEHVNYTQEGFAAGLIRVDSHLG
                     THLNTKGFHMSPIVFGAVPSLHSAIAFQCFLFLVSRSTSLKHRFSNAGGFTMHNNDSS
                     TFKLSEEDSEDEGDNSIPPTIGPNDLEMEPLGTVEPVDISNERSSSPSSSFTVSSNER
                     STGGGDGSIINSNGNKKPLQFVHLYDEDTNFTNKWIFKIVNDGFIPKFWAILYIILQW
                     WATMYLDHHYRFDLFVGVLYAMTSFIIINWFVLQPKVLKKWIHIRLGDKVDTRNEART
                     FGMRVFCGTKMEWFFDPLA"
     gene            <592439..>592948
                     /gene="SNF11"
                     /locus_tag="YDR073W"
                     /db_xref="GeneID:851645"
     mRNA            <592439..>592948
                     /gene="SNF11"
                     /locus_tag="YDR073W"
                     /product="Snf11p"
                     /transcript_id="NM_001180381.3"
                     /db_xref="GI:398365424"
                     /db_xref="GeneID:851645"
     CDS             592439..592948
                     /gene="SNF11"
                     /locus_tag="YDR073W"
                     /note="Subunit of the SWI/SNF chromatin remodeling
                     complex; involved in transcriptional regulation; interacts
                     with a highly conserved 40-residue sequence of Snf2p;
                     relocates to the cytosol under hypoxic conditions"
                     /codon_start=1
                     /product="Snf11p"
                     /protein_id="NP_010358.3"
                     /db_xref="GI:398365425"
                     /db_xref="SGD:S000002480"
                     /db_xref="GeneID:851645"
                     /translation="MSSEIAYSNTNTNTENENRNTGAGVDVNTNANANANATANATAN
                     ATANATAELNLPTVDEQRQYKVQLLLHINSILLARVIQMNNSLQNNLQNNINNSNNNN
                     IIRIQQLISQFLKRVHANLQCISQINQGVPSAKPLILTPPQLANQQQPPQDILSKLYL
                     LLARVFEIW"
     gene            <593893..>596583
                     /gene="TPS2"
                     /locus_tag="YDR074W"
                     /gene_synonym="HOG2; PFK3"
                     /db_xref="GeneID:851646"
     mRNA            <593893..>596583
                     /gene="TPS2"
                     /locus_tag="YDR074W"
                     /gene_synonym="HOG2; PFK3"
                     /product="trehalose-phosphatase TPS2"
                     /transcript_id="NM_001180382.1"
                     /db_xref="GI:296143428"
                     /db_xref="GeneID:851646"
     CDS             593893..596583
                     /gene="TPS2"
                     /locus_tag="YDR074W"
                     /gene_synonym="HOG2; PFK3"
                     /EC_number="3.1.3.12"
                     /note="Phosphatase subunit of the trehalose-6-P
                     synthase/phosphatase complex; involved in synthesis of the
                     storage carbohydrate trehalose; expression is induced by
                     stress conditions and repressed by the Ras-cAMP pathway;
                     protein abundance increases in response to DNA replication
                     stress"
                     /codon_start=1
                     /product="trehalose-phosphatase TPS2"
                     /protein_id="NP_010359.1"
                     /db_xref="GI:6320279"
                     /db_xref="SGD:S000002481"
                     /db_xref="GeneID:851646"
                     /translation="MTTTAQDNSPKKRQRIINCVTQLPYKIQLGESNDDWKISATTGN
                     SALFSSLEYLQFDSTEYEQHVVGWTGEITRTERNLFTREAKEKPQDLDDDPLYLTKEQ
                     INGLTTTLQDHMKSDKEAKTDTTQTAPVTNNVHPVWLLRKNQSRWRNYAEKVIWPTFH
                     YILNPSNEGEQEKNWWYDYVKFNEAYAQKIGEVYRKGDIIWIHDYYLLLLPQLLRMKF
                     NDESIIIGYFHHAPWPSNEYFRCLPRRKQILDGLVGANRICFQNESFSRHFVSSCKRL
                     LDATAKKSKNSSNSDQYQVSVYGGDVLVDSLPIGVNTTQILKDAFTKDIDSKVLSIKQ
                     AYQNKKIIIGRDRLDSVRGVVQKLRAFETFLAMYPEWRDQVVLIQVSSPTANRNSPQT
                     IRLEQQVNELVNSINSEYGNLNFSPVQHYYMRIPKDVYLSLLRVADLCLITSVRDGMN
                     TTALEYVTVKSHMSNFLCYGNPLILSEFSGSSNVLKDAIVVNPWDSVAVAKSINMALK
                     LDKEEKSNLESKLWKEVPTIQDWTNKFLSSLKEQASSNDDMERKMTPALNRPVLLENY
                     KQAKRRLFLFDYDGTLTPIVKDPAAAIPSARLYTILQKLCADPHNQIWIISGRDQKFL
                     NKWLGGKLPQLGLSAEHGCFMKDVSCQDWVNLTEKVDMSWQVRVNEVMEEFTTRTPGS
                     FIERKKVALTWHYRRTVPELGEFHAKELKEKLLSFTDDFDLEVMDGKANIEVRPRFVN
                     KGEIVKRLVWHQHGKPQDMLKGISEKLPKDEMPDFVLCLGDDFTDEDMFRQLNTIETC
                     WKEKYPDQKNQWGNYGFYPVTVGSASKKTVAKAHLTDPQQVLETLGLLVGDVSLFQSA
                     GTVDLDSRGHVKNSESSLKSKLASKAYVMKRSASYTGAKV"
     gene            <597156..>598082
                     /gene="PPH3"
                     /locus_tag="YDR075W"
                     /db_xref="GeneID:851647"
     mRNA            <597156..>598082
                     /gene="PPH3"
                     /locus_tag="YDR075W"
                     /product="phosphoprotein phosphatase PP4 catalytic subunit
                     PPH3"
                     /transcript_id="NM_001180383.1"
                     /db_xref="GI:296143429"
                     /db_xref="GeneID:851647"
     CDS             597156..598082
                     /gene="PPH3"
                     /locus_tag="YDR075W"
                     /EC_number="3.1.3.16"
                     /note="Catalytic subunit of protein phosphatase PP4
                     complex; active complex is composed of Pph3p and Psy2p,
                     with Psy4p apparently providing additional substrate
                     specificity in some cases; regulates recovery from the DNA
                     damage checkpoint and also the gene conversion- and
                     single-strand annealing-mediated pathways of meiotic
                     double-strand break repair; involved in activation of
                     Gln3p to alleviate nitrogen catabolite repression; Pph3p
                     and Psy2p localize to foci on meiotic chromosomes"
                     /codon_start=1
                     /product="phosphoprotein phosphatase PP4 catalytic subunit
                     PPH3"
                     /protein_id="NP_010360.1"
                     /db_xref="GI:6320280"
                     /db_xref="SGD:S000002482"
                     /db_xref="GeneID:851647"
                     /translation="MMDLDKIIASLRDGKHIPEETVFRLCLNSQELLMNEGNVTQVDT
                     PVTICGDIHGQLHDLLTLFEKSGGVEKTRYIFLGDFVDRGFYSLESFLLLLCYKLRYP
                     DRITLIRGNHETRQITKVYGFYDEVVRKYGNSNVWRYCCEVFDYLSLGAIINNSIFCV
                     HGGLSPDMTTVDEIRTIDRKQEVPHEGAMCDLLWSDPEDVDTWSLSPRGAGFLFGKRE
                     VDQFLEKNNVELIARAHQLVMEGYKEMFDGGLVTVWSAPNYCYRCGNVAAVLKIDDDL
                     NREYTIFEAVQAQNEVGNAIIPTKKSQMDYFL"
     gene            <598468..>599688
                     /gene="RAD55"
                     /locus_tag="YDR076W"
                     /db_xref="GeneID:851648"
     mRNA            <598468..>599688
                     /gene="RAD55"
                     /locus_tag="YDR076W"
                     /product="Rad55p"
                     /transcript_id="NM_001180384.3"
                     /db_xref="GI:398365442"
                     /db_xref="GeneID:851648"
     CDS             598468..599688
                     /gene="RAD55"
                     /locus_tag="YDR076W"
                     /note="Protein that stimulates strand exchange; stimulates
                     strand exchange by stabilizing the binding of Rad51p to
                     single-stranded DNA; involved in the recombinational
                     repair of double-strand breaks in DNA during vegetative
                     growth and meiosis; forms heterodimer with Rad57p"
                     /codon_start=1
                     /product="Rad55p"
                     /protein_id="NP_010361.3"
                     /db_xref="GI:398365443"
                     /db_xref="SGD:S000002483"
                     /db_xref="GeneID:851648"
                     /translation="MSLGIPLSQLIVESPKPLSSGITGLDEILNLGFQARSIYEIFGP
                     PGIGKTNFGIQLVCNSLEGIQQSEINDDKILWIETFQEMPINILRERFQKFKIVEENV
                     KRVRITKFGQLLYFFQNLFKLSQSVRYKLVIIDGFSQLVCDHLCTLSKRGGGMIDKTI
                     HELKCRHLILIFTVMTKYTHSTGSTIIVLNDCMNTAFQSNEFESLEEYYEILDDGSNF
                     FVNSNNERRKNNVHILKSALVANIAMGSKDSTWEVFLRDRIGLFRDWNEQVDETVFVK
                     SKRVKASSSQSNEGCTTIKEMRINKRNFENLRIAIVFNLHGEDRKREGRNLKRSRSSD
                     DRNYIVKFDFDKATGQLRDIIDLKPDTANIASFPTLSTSSSSCSQVFNNIDSNDNPLP
                     NAEGKEEIIYDSEG"
     gene            <600793..>601809
                     /gene="SED1"
                     /locus_tag="YDR077W"
                     /db_xref="GeneID:851649"
     mRNA            <600793..>601809
                     /gene="SED1"
                     /locus_tag="YDR077W"
                     /product="Sed1p"
                     /transcript_id="NM_001180385.3"
                     /db_xref="GI:398365448"
                     /db_xref="GeneID:851649"
     CDS             600793..601809
                     /gene="SED1"
                     /locus_tag="YDR077W"
                     /note="Major stress-induced structural GPI-cell wall
                     glycoprotein; associates with translating ribosomes,
                     possible role in mitochondrial genome maintenance; ORF
                     contains two distinct variable minisatellites; SED1 has a
                     paralog, SPI1, that arose from the whole genome
                     duplication"
                     /codon_start=1
                     /product="Sed1p"
                     /protein_id="NP_010362.3"
                     /db_xref="GI:398365449"
                     /db_xref="SGD:S000002484"
                     /db_xref="GeneID:851649"
                     /translation="MKLSTVLLSAGLASTTLAQFSNSTSASSTDVTSSSSISTSSGSV
                     TITSSEAPESDNGTSTAAPTETSTEAPTTAIPTNGTSTEAPTTAIPTNGTSTEAPTDT
                     TTEAPTTALPTNGTSTEAPTDTTTEAPTTGLPTNGTTSAFPPTTSLPPSNTTTTPPYN
                     PSTDYTTDYTVVTEYTTYCPEPTTFTTNGKTYTVTEPTTLTITDCPCTIEKPTTTSTT
                     EYTVVTEYTTYCPEPTTFTTNGKTYTVTEPTTLTITDCPCTIEKSEAPESSVPVTESK
                     GTTTKETGVTTKQTTANPSLTVSTVVPVSSSASSHSVVINSNGANVVVPGALGLAGVA
                     MLFL"
     gene            complement(<602198..>602869)
                     /gene="SHU2"
                     /locus_tag="YDR078C"
                     /db_xref="GeneID:851650"
     mRNA            complement(<602198..>602869)
                     /gene="SHU2"
                     /locus_tag="YDR078C"
                     /product="Shu2p"
                     /transcript_id="NM_001180386.1"
                     /db_xref="GI:296143432"
                     /db_xref="GeneID:851650"
     CDS             complement(602198..602869)
                     /gene="SHU2"
                     /locus_tag="YDR078C"
                     /note="Component of the Shu complex, which promotes
                     error-free DNA repair; Shu complex mediates inhibition of
                     Srs2p function"
                     /codon_start=1
                     /product="Shu2p"
                     /protein_id="NP_010363.1"
                     /db_xref="GI:6320283"
                     /db_xref="SGD:S000002485"
                     /db_xref="GeneID:851650"
                     /translation="MSKDVIEYSKLFAKLVNTNDDTKLDDTIASFLYYMFPRELFIRA
                     ISLLESSDMFIYILDRVHNKEGNEHTSLIDVLVDEFYKGSSNSLLEYRLIVKDTNDGA
                     PPILVDIAHWFCSCEEFCKYFHEALEKTDEKEELHDVLINEVDDHLQFSDDRFAQLDP
                     HSLSKQWYFKFDKVCCSHLLAFSILLRSSINVLKFFTVNSNKVFVIAIDNIDEWLNLH
                     INIVE"
     gene            <603064..>603399
                     /gene="PET100"
                     /locus_tag="YDR079W"
                     /db_xref="GeneID:851651"
     mRNA            <603064..>603399
                     /gene="PET100"
                     /locus_tag="YDR079W"
                     /product="Pet100p"
                     /transcript_id="NM_001180387.1"
                     /db_xref="GI:296143433"
                     /db_xref="GeneID:851651"
     CDS             603064..603399
                     /gene="PET100"
                     /locus_tag="YDR079W"
                     /note="Chaperone that facilitates the assembly of
                     cytochrome c oxidase; integral to the mitochondrial inner
                     membrane; interacts with a subcomplex of subunits VII,
                     VIIa, and VIII (Cox7p, Cox9p, and Cox8p) but not with the
                     holoenzyme"
                     /codon_start=1
                     /product="Pet100p"
                     /protein_id="NP_010364.1"
                     /db_xref="GI:6320284"
                     /db_xref="SGD:S000002486"
                     /db_xref="GeneID:851651"
                     /translation="MGLFNNFKFKYTRAQLEIFRFSFCLLAPVAVMYYIGTDTDKKLN
                     VPGFWPDPATLNQIPKEPYEIKAELARMKKERLEKRLRLEKKIQEEFGLDLEEEKEKI
                     KRDLALKKG"
     gene            complement(<603593..>603811)
                     /gene="TFB5"
                     /locus_tag="YDR079C-A"
                     /db_xref="GeneID:851652"
     mRNA            complement(<603593..>603811)
                     /gene="TFB5"
                     /locus_tag="YDR079C-A"
                     /product="TFIIH complex subunit TFB5"
                     /transcript_id="NM_001184469.3"
                     /db_xref="GI:398365464"
                     /db_xref="GeneID:851652"
     CDS             complement(603593..603811)
                     /gene="TFB5"
                     /locus_tag="YDR079C-A"
                     /note="Component of RNA polymerase II general
                     transcription factor TFIIH; involved in transcription
                     initiation and in nucleotide-excision repair; relocalizes
                     to the cytosol in response to hypoxia; homolog of
                     Chlamydomonas reinhardtii REX1-S protein involved in DNA
                     repair"
                     /codon_start=1
                     /product="TFIIH complex subunit TFB5"
                     /protein_id="NP_076886.3"
                     /db_xref="GI:398365465"
                     /db_xref="SGD:S000007603"
                     /db_xref="GeneID:851652"
                     /translation="MARARKGALVQCDPSIKALILQIDAKMSDIVLEELDDTHLLVNP
                     SKVEFVKHELNRLLSKNIYNPMDEEENQ"
     gene            <604008..>606986
                     /gene="VPS41"
                     /locus_tag="YDR080W"
                     /gene_synonym="CVT8; FET2; SVL2; VAM2; VPL20"
                     /db_xref="GeneID:851653"
     mRNA            <604008..>606986
                     /gene="VPS41"
                     /locus_tag="YDR080W"
                     /gene_synonym="CVT8; FET2; SVL2; VAM2; VPL20"
                     /product="Vps41p"
                     /transcript_id="NM_001180388.3"
                     /db_xref="GI:398365474"
                     /db_xref="GeneID:851653"
     CDS             604008..606986
                     /gene="VPS41"
                     /locus_tag="YDR080W"
                     /gene_synonym="CVT8; FET2; SVL2; VAM2; VPL20"
                     /note="Vacuolar membrane protein that is a subunit of the
                     HOPS complex; essential for membrane docking and fusion at
                     the Golgi-to-endosome and endosome-to-vacuole stages of
                     protein transport; the homotypic vacuole fusion and
                     vacuole protein sorting complex is also known as the HOPS
                     complex"
                     /codon_start=1
                     /product="Vps41p"
                     /protein_id="NP_010365.3"
                     /db_xref="GI:398365475"
                     /db_xref="SGD:S000002487"
                     /db_xref="GeneID:851653"
                     /translation="MTTDNHQNDSVLDQQSGERTIDESNSISDENNVDNKREDVNVTS
                     PTKSVSCISQAENGVASRTDESTITGSATDAETGDDDDDDDDDDDEDEDDEDEPPLLK
                     YTRISQLPKNFFQRDSISSCLFGDTFFAFGTHSGILHLTTCAFEPIKTIKCHRSSILC
                     INTDGKYFATGSIDGTVIIGSMDDPQNITQYDFKRPINSVALHSNFQASRMFVSGGMA
                     GDVVLSQRNWLGNRIDIVLNKKKKKKTRKDDLSSDMKGPIMGIYTMGDLILWMDDDGI
                     TFCDVPTRSQLLNIPFPSRIFNVQDVRPDLFRPHVHFLESDRVVIGWGSNIWLFKVSF
                     TKDSNSIKSGDSNSQSNNMSHFNPTTNIGSLLSSAASSFRGTPDKKVELECHFTVSML
                     ITGLASFKDDQLLCLGFDIDIEEEATIDEDMKEGKNFSKRPENLLAKGNAPELKIVDL
                     FNGDEIYNDEVIMKNYEKLSINDYHLGKHIDKTTPEYYLISSNDAIRVQELSLKDHFD
                     WFMERKQYYKAWKIGKYVIGSEERFSIGLKFLNSLVTKKDWGTLVDHLNIIFEETLNS
                     LDSNSYDVTQNVLKEWADIIEILITSGNIVEIAPLIPKKPALRKSVYDDVLHYFLAND
                     MINKFHEYITKWDLKLFSVEDFEEELETRIEAASEPTASSKEEGSNITYRTELVHLYL
                     KENKYTKAIPHLLKAKDLRALTIIKIQNLLPQYLDQIVDIILLPYKGEISHISKLSIF
                     EIQTIFNKPIDLLFENRHTISVARIYEIFEHDCPKSFKKILFCYLIKFLDTDDSFMIS
                     PYENQLIELYSEYDRQSLLPFLQKHNNYNVESAIEVCSSKLGLYNELIYLWGKIGETK
                     KALSLIIDELKNPQLAIDFVKNWGDSELWEFMINYSLDKPNFTKAILTCSDETSEIYL
                     KVIRGMSDDLQIDNLQDIIKHIVQENSLSLEVRDNILVIINDETKKFANEFLKIRSQG
                     KLFQVDESDIEINDDLNGVL"
     gene            complement(<607304..>610081)
                     /gene="PDC2"
                     /locus_tag="YDR081C"
                     /db_xref="GeneID:851654"
     mRNA            complement(<607304..>610081)
                     /gene="PDC2"
                     /locus_tag="YDR081C"
                     /product="Pdc2p"
                     /transcript_id="NM_001180389.1"
                     /db_xref="GI:296143436"
                     /db_xref="GeneID:851654"
     CDS             complement(607304..610081)
                     /gene="PDC2"
                     /locus_tag="YDR081C"
                     /note="Transcription factor for thiamine-regulated genes;
                     required for expression of the two isoforms of pyruvate
                     decarboxylase (PDC1 and PDC5) along with thiamine
                     biosynthetic genes; binds a DNA sequence in the PDC5
                     promoter; mutant fails to grow on 2% glucose and thus is
                     scored as inviable under standard conditions"
                     /codon_start=1
                     /product="Pdc2p"
                     /protein_id="NP_010366.1"
                     /db_xref="GI:6320286"
                     /db_xref="SGD:S000002488"
                     /db_xref="GeneID:851654"
                     /translation="MLSIQQRYNICLMAERHPKWTQLELAKWAYETFQLPKIPSQGTI
                     SRLLARKSTYMNCKEHEKDANRLRKPNNLLVRKILQEWISQSLWNGIPITSPIIQDTA
                     QAVWHRIPAEHREGNGSFSYKWISNFLSKMDVNISVLDEELPKTPKVWTFEERDVLKA
                     YFSKIPPKDLFTLDEAFLSYNLPLDYAQYEASSIQRRIEVATVMLCSNLDGSEKLKPV
                     VVGKYDSYKSFRNYFPNEPNDPVSQSMLGTKMAKKFDISYHSNRKAWLTSNLFHNWLV
                     RWDKRLVAVNRKIWIVLDDSCCHRIINLRLQNIKLVYTSSNSKFLPFNWGVWDEFKTR
                     YRIQQYQALIDLQNRISKNIQNKNKSERNECIPNGKKCLISFEQSQLTMSNAFKFIKK
                     AWDDIPVDAIKANWKSSGLLPPEMIHLNENVSMAFKKNEVLESVLNRLCDEYYCVKKW
                     EYEMLLDLNIENKNTNFLSTEELVESAIVEPCEPDFDTAPKGNEVHDDNFDVSVFANE
                     DDNNQNHLSMSQASHNPDYNSNHSNNAIENTNNRGSNNNNNNNGSSNNINDNDSSVKY
                     LQQNTVDNSTKTGNPGQPNISSMESQRNSSTTDLVVDGNYDVNFNGLLNDPYNTMKQP
                     GPLDYNVSTLIDKPNLFLSPDLDLSTVGVDMQLPSSEYFSEVFSSAIRNNEKAASDQN
                     KSTDELPSSTAMANSNSITTALLESRNQAQPFDVPHMNGLLSDTSKSGHSVNSSNAIS
                     QNSLNNFQHNSASVAEASSPSITPSPVAINSTGAPARSIISAPIDSNSSASSPSALEH
                     LEGAVSGMSPSSTTILSNLQTNINIAKSLSTIMKHAESNEISLTKETINELNFNYLTL
                     LKRIKKTRKQLNSESIKINSKNAQDHLETLLSGAAAAAATSANNLDLPTGGSNLPDSN
                     NLHLPGNTGFF"
     gene            <610441..>611925
                     /gene="STN1"
                     /locus_tag="YDR082W"
                     /db_xref="GeneID:851655"
     mRNA            <610441..>611925
                     /gene="STN1"
                     /locus_tag="YDR082W"
                     /product="Stn1p"
                     /transcript_id="NM_001180390.1"
                     /db_xref="GI:296143437"
                     /db_xref="GeneID:851655"
     CDS             610441..611925
                     /gene="STN1"
                     /locus_tag="YDR082W"
                     /note="Telomere end-binding and capping protein; plays a
                     key role with Pol12p in linking telomerase action with
                     completion of lagging strand synthesis, and in a
                     regulatory step required for telomere capping; similar to
                     human Stn1"
                     /codon_start=1
                     /product="Stn1p"
                     /protein_id="NP_010367.1"
                     /db_xref="GI:6320287"
                     /db_xref="SGD:S000002489"
                     /db_xref="GeneID:851655"
                     /translation="MDKYGHIAHQEGDVCYYIPRLFKYNSYYSGTEDVRIFVGDLKYR
                     MRVSLQICEKYYDRRLSMLFWKNHPLQQIHLIGCIIGLQFKWIGKQEYIFFQLDDCTS
                     DSSLVGYTSDMRFLTCKVKKDSILSWGLNITDLIGLTLHVYGQASLNYQELQVEYLRL
                     CYSLTEEIDHWKITMNMREQLDTPWSLSDFVIGELFTQEQEWTPETSQIEVVNPDFVG
                     IGYKTPESKRNETTFIEQLQEERLKDELEIISPYNSTDTSNSVHSLSFRFVSSLKDFP
                     ETHFLNSGDQIDNGNDEQLKKLEYQSANLPVMIPNRTSAKSNLMLILLGLQMKEISNS
                     DLYKLKEVRSVVTSLASFLFQQQNVGVMKSFDSLEKEAFRDLVNRLVSQGLIGLKDKT
                     SETFDLLPLKNLFEYAEKRISVLMKLQCYTGTVQLSHVQEKLHLPYITTNGIVDVFKE
                     CLKRTKKQYPEVLKNWWIDLDPKNGMEDQNSGILLHLEYAAAYS"
     gene            <612073..>613251
                     /gene="RRP8"
                     /locus_tag="YDR083W"
                     /db_xref="GeneID:851656"
     mRNA            <612073..>613251
                     /gene="RRP8"
                     /locus_tag="YDR083W"
                     /product="Rrp8p"
                     /transcript_id="NM_001180391.3"
                     /db_xref="GI:398365486"
                     /db_xref="GeneID:851656"
     CDS             612073..613251
                     /gene="RRP8"
                     /locus_tag="YDR083W"
                     /EC_number="2.1.1.287"
                     /note="Nucleolar S-adenosylmethionine-dependent rRNA
                     methyltransferase; methylates adenine (m1A) of the large
                     subunit (LSU) rRNA at position 645; involved in pre-rRNA
                     cleavage at site A2; mutation is synthetically lethal with
                     a gar1 mutation; deletion disrupts telomere maintenance by
                     influencing the expression of neighboring gene STN1"
                     /codon_start=1
                     /product="Rrp8p"
                     /protein_id="NP_010368.5"
                     /db_xref="GI:398365487"
                     /db_xref="SGD:S000002490"
                     /db_xref="GeneID:851656"
                     /translation="MALFNVEGWSIKTKTVAFDNKTNKSSKDKKKNNRKNGKLTREQK
                     LKEETEAELKEQVEDIPSEGSVAKDIPKKNQEKSDQNETSKKRKHDEEAPLMQVKENI
                     EKPTKKQLTPLQQKMMAKLTGSRFRWINEQLYTISSDEALKLIKEQPQLFDEYHDGFR
                     SQVQAWPENPVDVFVDQIRYRCMKPVNAPGGLPGLKDSKEIVIADMGCGEAQLALEIN
                     NFFKNYNKKAKKYLKRRHKVHSFDLKKANERITVADIRNVPLPDESCTIVVFCLALMG
                     TNFLDFIKEAYRILAPRGELWIAEIKSRFSDGKGNEFVDALKLMGFFHKKTFDENKMF
                     TRFEFFKPPAEIIEERRQKLERRQKFIEVETEKEELEKKRRKIAEGKWLLKPCIYKRR
                     "
     gene            complement(<613405..>614004)
                     /gene="TVP23"
                     /locus_tag="YDR084C"
                     /db_xref="GeneID:851657"
     mRNA            complement(<613405..>614004)
                     /gene="TVP23"
                     /locus_tag="YDR084C"
                     /product="Tvp23p"
                     /transcript_id="NM_001180392.3"
                     /db_xref="GI:398365490"
                     /db_xref="GeneID:851657"
     CDS             complement(613405..614004)
                     /gene="TVP23"
                     /locus_tag="YDR084C"
                     /note="Integral membrane protein; localized to late Golgi
                     vesicles along with the v-SNARE Tlg2p; green fluorescent
                     protein (GFP)-fusion protein localizes to the cytoplasm in
                     a punctate pattern"
                     /codon_start=1
                     /product="Tvp23p"
                     /protein_id="NP_010369.3"
                     /db_xref="GI:398365491"
                     /db_xref="SGD:S000002491"
                     /db_xref="GeneID:851657"
                     /translation="MDQARNFYNTILKSSHPLLLSFHLAGKAVPIVFYIIGSMFLNFT
                     PQFITVVLLLSFDFYLTKNITGRKLVQLRWWYDSTDVNKDSNFTFESYKQYAPGPPIN
                     AIDSKLFWWSMYVTPVIWGVFAVLCLLRLKIFYLILVIVAMCLTAWNTYGFRCCDRWE
                     PNSGQSDGQDTNNWFALPSVPGFENLSRLANIQSFFQRQ"
     gene            complement(<614288..>616150)
                     /gene="AFR1"
                     /locus_tag="YDR085C"
                     /db_xref="GeneID:851658"
     mRNA            complement(<614288..>616150)
                     /gene="AFR1"
                     /locus_tag="YDR085C"
                     /product="Afr1p"
                     /transcript_id="NM_001180393.1"
                     /db_xref="GI:296143440"
                     /db_xref="GeneID:851658"
     CDS             complement(614288..616150)
                     /gene="AFR1"
                     /locus_tag="YDR085C"
                     /note="Protein required for pheromone-induced projection
                     (shmoo) formation; regulates septin architecture during
                     mating; has an RVXF motif that mediates targeting of Glc7p
                     to mating projections; interacts with Cdc12p; AFR1 has a
                     paralog, YER158C, that arose from the whole genome
                     duplication"
                     /codon_start=1
                     /product="Afr1p"
                     /protein_id="NP_010370.1"
                     /db_xref="GI:6320290"
                     /db_xref="SGD:S000002492"
                     /db_xref="GeneID:851658"
                     /translation="MEGSYLSAQENQPIPERLIPRSNSTSNLFALSSTFSKLNVRNDA
                     DYNYSNPNKKRHIYSGEIDCRSVTAARKFPVRSCSMTAAQQRKRTALFTVRERNSYHE
                     GFNNDQDYVSQYQKPQYTFGVYKELTPYQLQRSKMKRSFQFPNGEIYKPKLDGKCTHS
                     LKKPELNSRDSSLFKFSEKKGRNLSKDFVGPHNGTSVIHIPPNDTGYGVNSLELNTSV
                     PSTIKSSVSSTSPISAVNTLTSLPESQTDDDDGYENKTVTISYCFENTVNEKHGSHIE
                     KLDLSTKEKTKPTTNSGLFDRKKKTILGTEKYRCIKSQSKLKLGSVLKKLWRTSGNSN
                     TKHGKKDTKRRRIPIDDMVTHSDGNSEAENDIELMDANLDGIEFDDDETLMDTDSIFD
                     DLLSKENDKYDLRRRQLEIRQKLHETSHNDDGKVSFRDTEKHNVNEGLIDKTIIEEFS
                     KLGEYIIDTRNQPPPRSSKRPSLDDNESARYFYNISTDLRQSLSGPISLPMHVGNDMV
                     NRLRNDWEYIRFEDRRNSLPDSSFDKVETPPKPIKKDVRFAKEVCLASTWSSNAYERA
                     NPEFIMNRHRLLWMMKVHPSMNSAMNEIKLELNSYKKNEMVVHENSKCFTHYLI"
     gene            complement(<616928..>617170)
                     /gene="SSS1"
                     /locus_tag="YDR086C"
                     /db_xref="GeneID:851659"
     mRNA            complement(<616928..>617170)
                     /gene="SSS1"
                     /locus_tag="YDR086C"
                     /product="translocon subunit SSS1"
                     /transcript_id="NM_001180394.1"
                     /db_xref="GI:296143441"
                     /db_xref="GeneID:851659"
     CDS             complement(616928..617170)
                     /gene="SSS1"
                     /locus_tag="YDR086C"
                     /note="Subunit of the Sec61p translocation complex
                     (Sec61p-Sss1p-Sbh1p); this complex forms a channel for
                     passage of secretory proteins through the endoplasmic
                     reticulum membrane, and of the Ssh1p complex
                     (Ssh1p-Sbh2p-Sss1p); interacts with Ost4p and Wbp1p"
                     /codon_start=1
                     /product="translocon subunit SSS1"
                     /protein_id="NP_010371.1"
                     /db_xref="GI:6320291"
                     /db_xref="SGD:S000002493"
                     /db_xref="GeneID:851659"
                     /translation="MARASEKGEEKKQSNNQVEKLVEAPVEFVREGTQFLAKCKKPDL
                     KEYTKIVKAVGIGFIAVGIIGYAIKLIHIPIRYVIV"
     gene            complement(<617470..>618306)
                     /gene="RRP1"
                     /locus_tag="YDR087C"
                     /db_xref="GeneID:851660"
     mRNA            complement(<617470..>618306)
                     /gene="RRP1"
                     /locus_tag="YDR087C"
                     /product="Rrp1p"
                     /transcript_id="NM_001180395.3"
                     /db_xref="GI:398365508"
                     /db_xref="GeneID:851660"
     CDS             complement(617470..618306)
                     /gene="RRP1"
                     /locus_tag="YDR087C"
                     /note="Essential evolutionarily conserved nucleolar
                     protein; necessary for biogenesis of 60S ribosomal
                     subunits and for processing of pre-rRNAs to mature rRNA;
                     associated with several distinct 66S pre-ribosomal
                     particles"
                     /codon_start=1
                     /product="Rrp1p"
                     /protein_id="NP_010372.3"
                     /db_xref="GI:398365509"
                     /db_xref="SGD:S000002494"
                     /db_xref="GeneID:851660"
                     /translation="METSNFVKQLSSNNRKTRVNALEALKKYLTAKQFKENKQIEFNK
                     LWKGLYYAMWFSDRPRPQQRLANELGELHGLYFDPKDNSTADELTTNDKAFIKFSRGF
                     WKVMCFEWFNIDRYRLDKYLLLIRRVLFSQLKYLQSRNWDKKLVDEYIKKVLRWLPLS
                     GSPKVYTGIPIHIVDILLDEWERLLKDGDEDDEDEENKEEEMRKIAESAKKTPLADVI
                     AIFQDIVADYNNSKVLREKIKEDLFSDTRLVSWDILEGETQHNDSSNESEEEEEEEWK
                     GF"
     gene            complement(<618497..>619645)
                     /gene="SLU7"
                     /locus_tag="YDR088C"
                     /gene_synonym="SLT17"
                     /db_xref="GeneID:851661"
     mRNA            complement(<618497..>619645)
                     /gene="SLU7"
                     /locus_tag="YDR088C"
                     /gene_synonym="SLT17"
                     /product="Slu7p"
                     /transcript_id="NM_001180396.3"
                     /db_xref="GI:398365514"
                     /db_xref="GeneID:851661"
     CDS             complement(618497..619645)
                     /gene="SLU7"
                     /locus_tag="YDR088C"
                     /gene_synonym="SLT17"
                     /note="RNA splicing factor; required for ATP-independent
                     portion of 2nd catalytic step of spliceosomal RNA
                     splicing; interacts with Prp18p; contains zinc knuckle
                     domain"
                     /codon_start=1
                     /product="Slu7p"
                     /protein_id="NP_010373.3"
                     /db_xref="GI:398365515"
                     /db_xref="SGD:S000002495"
                     /db_xref="GeneID:851661"
                     /translation="MNNNSRNNENRSTINRNKRQLQQAKEKNENIHIPRYIRNQPWYY
                     KDTPKEQEGKKPGNDDTSTAEGGEKSDYLVHHRQKAKGGALDIDNNSEPKIGMGIKDE
                     FKLIRPQKMSVRDSHSLSFCRNCGEAGHKEKDCMEKPRKMQKLVPDLNSQKNNGTVLV
                     RATDDDWDSRKDRWYGYSGKEYNELISKWERDKRNKIKGKDKSQTDETLWDTDEEIEL
                     MKLELYKDSVGSLKKDDADNSQLYRTSTRLREDKAAYLNDINSTESNYDPKSRLYKTE
                     TLGAVDEKSKMFRRHLTGEGLKLNELNQFARSHAKEMGIRDEIEDKEKVQHVLVANPT
                     KYEYLKKKREQEETKQPKIVSIGDLEARKVDGTKQSEEQRNHLKDLYG"
     gene            complement(619969..620041)
                     /locus_tag="tR(ACG)D"
                     /db_xref="GeneID:851662"
     tRNA            complement(619969..620041)
                     /locus_tag="tR(ACG)D"
                     /product="tRNA-Arg"
                     /note="Arginine tRNA (tRNA-Arg), predicted by tRNAscan-SE
                     analysis; one of 6 nuclear tRNA genes containing the
                     tDNA-anticodon ACG (converted to ICG in the mature tRNA),
                     decodes CGU, CGC, and probably CGA codons into arginine,
                     one of 19 nuclear tRNAs for arginine"
                     /db_xref="SGD:S000006700"
                     /db_xref="GeneID:851662"
     gene            <622112..>624721
                     /locus_tag="YDR089W"
                     /db_xref="GeneID:851663"
     mRNA            <622112..>624721
                     /locus_tag="YDR089W"
                     /product="hypothetical protein"
                     /transcript_id="NM_001180397.1"
                     /db_xref="GI:296143444"
                     /db_xref="GeneID:851663"
     CDS             622112..624721
                     /locus_tag="YDR089W"
                     /note="hypothetical protein; deletion confers resistance
                     to nickel; contains an SPX domain, which is found in
                     proteins involved in phosphate homeostasis; relocalizes
                     from vacuole to cytoplasm upon DNA replication stress"
                     /codon_start=1
                     /product="hypothetical protein"
                     /protein_id="NP_010374.1"
                     /db_xref="GI:6320294"
                     /db_xref="SGD:S000002496"
                     /db_xref="GeneID:851663"
                     /translation="MKFEDRILNKSIPEWKFYNINYEKLKVAIKKVTAYDYDNPNDSG
                     MEKLLNQCSVAFDQEFQNVNLFVSLKIKEISTRILSVESSIIDFSKGLNKTSRNRFNL
                     RKLKIINAHVDDCNFELQLLSRFLIIQRIALRKLFKKLLNEFPQDSENPLTASEYVTS
                     IRNSESLRNGHEGISFMKLDLDPYLLEVSLIVDVLHDLENKLEDATEPAVEQRSLNRS
                     DESAHTSSSPEANNSSLPASPRSIPLLSNKKTSKMIDSSLEFDTALIDKAENLGRFLL
                     SSEDIEGLKFMLLNIGFRIIDDSIISTSKEILDTTDNINSAGNKSIRSAKSFNDLQHT
                     LSLSKQKNILPSAVQSNEKYVSISILDTVGNEGSPLLLTDDNINQHPNMIVSSTAEDT
                     CIVMCHVGGLRNHVVTNDLLLRDVKNILSAMRSGNDTKNISALINSLDPSPISKIALE
                     WIQSHRLKTIEPKLDFKRTRFISADNGDIYLIALDESITIGNVSTLPFPILEIKKLSR
                     SSGLSQTAINEDNKFKQLMKSVVTNEFQCSLIPPDLTTWKICLELVHSNELQNDLFQL
                     LLRDQYKLNSDDSLSPDEFFQLGKDRLEEEFDLTGPINNSQGSVDSGRRVRIHKKSKQ
                     SDNETKKKPIRYWNEFDEQEEDNLDNAFYIDTNGSRSTTDNEESLLLRNSPPDYGFIL
                     FSRNFINRTYDFCEKLRNLIRHDKKTSPDLFQNSKHPHCSSTNYGSVASFGSQSTSAS
                     YDDVQRYLQYQQQDIEDSQSIYEYRHDEVVTFLYLSALLTSCIMASVCLGIVLSLFRG
                     QSNNEIDLEIQNILIAIIIISLLVSLILICACLLLLFSRFTLAPIWHYVGCFTMFFSV
                     TGTVCYGMIEIFF"
     gene            complement(<625066..>625998)
                     /locus_tag="YDR090C"
                     /db_xref="GeneID:851664"
     mRNA            complement(<625066..>625998)
                     /locus_tag="YDR090C"
                     /product="hypothetical protein"
                     /transcript_id="NM_001180398.1"
                     /db_xref="GI:296143445"
                     /db_xref="GeneID:851664"
     CDS             complement(625066..625998)
                     /locus_tag="YDR090C"
                     /codon_start=1
                     /product="hypothetical protein"
                     /protein_id="NP_010375.1"
                     /db_xref="GI:6320295"
                     /db_xref="SGD:S000002497"
                     /db_xref="GeneID:851664"
                     /translation="MISEKAATALATIATVCWCVQLIPQIIYNWKKKDCTGLPPLMMF
                     LWVVSGIPFAIYFCVSKGNVILQVQPHLFMFFCSISFVQSCYYPPISMARSKIVMIVA
                     AIIAADVGMEVGFILWLRPLYEKGVKWPDLIFGISASVLLAVGLLPPYFELAKRKGRV
                     IGINFAFLFIDSLGAWLSIISVILGNMDIMGIILYSIVAGMELGIFASHFIWWCRFRF
                     LAKGNTFDEESGQAQKEEPDEKIEQDISKSDRNVTNYNLDNCSIPDDASSFADDFNIY
                     DSTDGGTLSRAQTLHAVHGVVVRTDPDRYSRLSV"
     gene            complement(<626708..>628534)
                     /gene="RLI1"
                     /locus_tag="YDR091C"
                     /db_xref="GeneID:851665"
     mRNA            complement(<626708..>628534)
                     /gene="RLI1"
                     /locus_tag="YDR091C"
                     /product="Rli1p"
                     /transcript_id="NM_001180399.3"
                     /db_xref="GI:398365536"
                     /db_xref="GeneID:851665"
     CDS             complement(626708..628534)
                     /gene="RLI1"
                     /locus_tag="YDR091C"
                     /note="Essential Fe-S protein; required for ribosome
                     biogenesis, translation initiation/termination;
                     facilitates binding of multifactor complex (MFC) of
                     initiation factors to small ribosomal subunit; Dom34-Hbs1
                     complex and Rli1p work in dissociating inactive ribosomes,
                     thereby facilitating translation restart; forms complex
                     with Lto1p and Yae1p; dependency on ROS-labile FeS
                     clusters, activity in nuclear ribosomal-subunit export
                     impaired by mild oxidative stress"
                     /codon_start=1
                     /product="Rli1p"
                     /protein_id="NP_010376.3"
                     /db_xref="GI:398365537"
                     /db_xref="SGD:S000002498"
                     /db_xref="GeneID:851665"
                     /translation="MSDKNSRIAIVSADKCKPKKCRQECKRSCPVVKTGKLCIEVTPT
                     SKIAFISEILCIGCGICVKKCPFDAIQIINLPTNLEAHVTHRYSANSFKLHRLPTPRP
                     GQVLGLVGTNGIGKSTALKILAGKQKPNLGRFDDPPEWQEIIKYFRGSELQNYFTKML
                     EDDIKAIIKPQYVDNIPRAIKGPVQKVGELLKLRMEKSPEDVKRYIKILQLENVLKRD
                     IEKLSGGELQRFAIGMSCVQEADVYMFDEPSSYLDVKQRLNAAQIIRSLLAPTKYVIC
                     VEHDLSVLDYLSDFVCIIYGVPSVYGVVTLPASVREGINIFLDGHIPAENLRFRTEAL
                     QFRIADATEDLQNDSASRAFSYPSLKKTQGDFVLNVEEGEFSDSEILVMMGENGTGKT
                     TLIKLLAGALKPDEGQDIPKLNVSMKPQKIAPKFPGTVRQLFFKKIRGQFLNPQFQTD
                     VVKPLRIDDIIDQEVQHLSGGELQRVAIVLALGIPADIYLIDEPSAYLDSEQRIICSK
                     VIRRFILHNKKTAFIVEHDFIMATYLADKVIVFEGIPSKNAHARAPESLLTGCNRFLK
                     NLNVTFRRDPNSFRPRINKLDSQMDKEQKSSGNYFFLDNTGI"
     rep_origin      628579..629921
                     /note="ARS420;
                     Putative replication origin; identified in multiple array
                     studies, not yet confirmed by plasmid-based assay"
                     /db_xref="SGD:S000130174"
     gene            <629876..>630605
                     /gene="UBC13"
                     /locus_tag="YDR092W"
                     /db_xref="GeneID:851666"
     mRNA            join(<629876..629905,630174..>630605)
                     /gene="UBC13"
                     /locus_tag="YDR092W"
                     /product="E2 ubiquitin-conjugating protein UBC13"
                     /transcript_id="NM_001180400.3"
                     /db_xref="GI:398365540"
                     /db_xref="GeneID:851666"
     CDS             join(629876..629905,630174..630605)
                     /gene="UBC13"
                     /locus_tag="YDR092W"
                     /EC_number="6.3.2.19"
                     /note="E2 ubiquitin-conjugating enzyme; involved in the
                     error-free DNA postreplication repair pathway; interacts
                     with Mms2p to assemble ubiquitin chains at the Ub Lys-63
                     residue; DNA damage triggers redistribution from the
                     cytoplasm to the nucleus"
                     /codon_start=1
                     /product="E2 ubiquitin-conjugating protein UBC13"
                     /protein_id="NP_010377.3"
                     /db_xref="GI:398365541"
                     /db_xref="SGD:S000002499"
                     /db_xref="GeneID:851666"
                     /translation="MASLPKRIIKETEKLVSDPVPGITAEPHDDNLRYFQVTIEGPEQ
                     SPYEDGIFELELYLPDDYPMEAPKVRFLTKIYHPNIDRLGRICLDVLKTNWSPALQIR
                     TVLLSIQALLASPNPNDPLANDVAEDWIKNEQGAKAKAREWTKLYAKKKPE"
     gene            <631282..>636120
                     /gene="DNF2"
                     /locus_tag="YDR093W"
                     /db_xref="GeneID:851667"
     mRNA            <631282..>636120
                     /gene="DNF2"
                     /locus_tag="YDR093W"
                     /product="aminophospholipid-translocating P4-type ATPase
                     DNF2"
                     /transcript_id="NM_001180401.1"
                     /db_xref="GI:296143448"
                     /db_xref="GeneID:851667"
     CDS             631282..636120
                     /gene="DNF2"
                     /locus_tag="YDR093W"
                     /EC_number="3.6.3.1"
                     /note="Aminophospholipid translocase (flippase); localizes
                     primarily to the plasma membrane; contributes to
                     endocytosis, protein transport and cell polarity; type 4
                     P-type ATPase; DNF2 has a paralog, DNF1, that arose from
                     the whole genome duplication"
                     /codon_start=1
                     /product="aminophospholipid-translocating P4-type ATPase
                     DNF2"
                     /protein_id="NP_010378.1"
                     /db_xref="GI:6320298"
                     /db_xref="SGD:S000002500"
                     /db_xref="GeneID:851667"
                     /translation="MSSPSKPTSPFVDDIEHESGSASNGLSSMSPFDDSFQFEKPSSA
                     HGNIEVAKTGGSVLKRQSKPMKDISTPDLSKVTFDGIDDYSNDNDINDDDELNGKKTE
                     IHEHENEVDDDLHSFQATPMPNTGGFEDVELDNNEGSNNDSQADHKLKRVRFGTRRNK
                     SGRIDINRSKTLKWAKKNFHNAIDEFSTKEDSLENSALQNRSDELRTVYYNLPLPEDM
                     LDEDGLPLAVYPRNKIRTTKYTPLTFFPKNILFQFHNFANIYFLILLILGAFQIFGVT
                     NPGFASVPLIVIVIITAIKDGIEDSRRTVLDLEVNNTRTHILSGVKNENVAVDNVSLW
                     RRFKKANTRALIKIFEYFSENLTAAGREKKLQKKREELRRKRNSRSFGPRGSLDSIGS
                     YRMSADFGRPSLDYENLNQTMSQANRYNDGENLVDRTLQPNPECRFAKDYWKNVKVGD
                     IVRVHNNDEIPADMILLSTSDVDGACYVETKNLDGETNLKVRQSLKCSKIIKSSRDIT
                     RTKFWVESEGPHANLYSYQGNFKWQDTQNGNIRNEPVNINNLLLRGCTLRNTKWAMGM
                     VIFTGDDTKIMINAGVTPTKKSRISRELNFSVILNFVLLFILCFTAGIVNGVYYKQKP
                     RSRDYFEFGTIGGSASTNGFVSFWVAVILYQSLVPISLYISVEIIKTAQAIFIYTDVL
                     LYNAKLDYPCTPKSWNISDDLGQIEYIFSDKTGTLTQNVMEFKKCTINGVSYGRAYTE
                     ALAGLRKRQGVDVESEGRREKEEIAKDRETMIDELRSMSDNTQFCPEDLTFVSKEIVE
                     DLKGSSGDHQQKCCEHFLLALALCHSVLVEPNKDDPKKLDIKAQSPDESALVSTARQL
                     GYSFVGSSKSGLIVEIQGVQKEFQVLNVLEFNSSRKRMSCIIKIPGSTPKDEPKALLI
                     CKGADSVIYSRLDRTQNDATLLEKTALHLEEYATEGLRTLCLAQRELTWSEYERWVKT
                     YDVAAASVTNREEELDKVTDVIERELILLGGTAIEDRLQDGVPDSIALLAEAGIKLWV
                     LTGDKVETAINIGFSCNVLNNDMELLVVKASGEDVEEFGSDPIQVVNNLVTKYLREKF
                     GMSGSEEELKEAKREHGLPQGNFAVIIDGDALKVALNGEEMRRKFLLLCKNCKAVLCC
                     RVSPAQKAAVVKLVKKTLDVMTLAIGDGSNDVAMIQSADVGVGIAGEEGRQAVMCSDY
                     AIGQFRYVTRLVLVHGKWCYKRLAEMIPQFFYKNVIFTLSLFWYGIYNNFDGSYLFEY
                     TYLTFYNLAFTSVPVILLAVLDQDVSDTVSMLVPQLYRVGILRKEWNQTKFLWYMLDG
                     VYQSVICFFFPYLAYHKNMVVTENGLGLDHRYFVGVFVTAIAVTSCNFYVFMEQYRWD
                     WFCGLFICLSLAVFYGWTGIWTSSSSSNEFYKGAARVFAQPAYWAVLFVGVLFCLLPR
                     FTIDCIRKIFYPKDIEIVREMWLRGDFDLYPQGYDPTDPSRPRINEIRPLTDFKEPIS
                     LDTHFDGVSHSQETIVTEEIPMSILNGEQGSRKGYRVSTTLERRDQLSPVTTTNNLPR
                     RSMASARGNKLRTSLDRTREEMLANHQLDTRYSVERARASLDLPGINHAETLLSQRSR
                     DR"
     gene            <637139..>639823
                     /gene="GIS1"
                     /locus_tag="YDR096W"
                     /db_xref="GeneID:851670"
     mRNA            <637139..>639823
                     /gene="GIS1"
                     /locus_tag="YDR096W"
                     /product="Gis1p"
                     /transcript_id="NM_001180404.1"
                     /db_xref="GI:296143449"
                     /db_xref="GeneID:851670"
     CDS             637139..639823
                     /gene="GIS1"
                     /locus_tag="YDR096W"
                     /note="Histone demethylase and transcription factor;
                     regulates genes during nutrient limitation; activity
                     modulated by proteasome-mediated proteolysis; has JmjC and
                     JmjN domain in N-terminus that interact, promoting
                     stability and proper transcriptional activity; contains
                     two transactivating domains downstream of Jmj domains and
                     a C-terminal DNA binding domain; relocalizes to the
                     cytosol in response to hypoxia; GIS1 has a paralog, RPH1,
                     that arose from the whole genome duplication"
                     /codon_start=1
                     /product="Gis1p"
                     /protein_id="NP_010381.1"
                     /db_xref="GI:6320301"
                     /db_xref="SGD:S000002503"
                     /db_xref="GeneID:851670"
                     /translation="MEIKPVEVIDGVPVFKPSMMEFANFQYFIDEITKFGIENGIVKV
                     IPPKEWLELLEGSPPAESLKTIQLDSPIQQQAKRWDKHENGVFSIENEYDNKSYNLTQ
                     WKNLAESLDSRISQGDFNDKTLKENCRVDSQQDCYDLAQLQILESDFWKTIAFSKPFY
                     AVDENSSIFPYDLTLWNLNNLPDSINSSNRRLLTGQSKCIFPWHLDEQNKCSINYLHF
                     GAPKQWYSIPSANTDQFLKILSKEPSSNKENCPAFIRHQNIITSPDFLRKNNIKFNRV
                     VQFQHEFIITFPYCMYSGFNYGYNFGESIEFILDQQAVVRKQPLKCGCGNKKEERKSG
                     PFSNLSYDSNESEQRGSITDNDNDLFQKVRSFDELLNHSSQELQNLEDNKNPLFSNIN
                     MNRPQSSSLRSTTPNGVNQFLNMNQTTISRISSPLLSRMMDLSNIVEPTLDDPGSKFK
                     RKVLTPQLPQMNIPSNSSNFGTPSLTNTNSLLSNITATSTNPSTTTNGSQNHNNVNAN
                     GINTSAAASINNNISSTNNSANNSSSNNNVSTVPSSMMHSSTLNGTSGLGGDNDDNML
                     ALSLATLANSATASPRLTLPPLSSPMNPNGHTSYNGNMMNNNSGNGSNGSNSYSNGVT
                     TAAATTTSAPHNLSIVSPNPTYSPNPLSLYLTNSKNPLNSGLAPLSPSTSNIPFLKRN
                     NVVTLNISREASKSPISSFVNDYRSPLGVSNPLMYSSTINDYSNGTGIRQNSNNINPL
                     DAGPSFSPLHKKPKILNGNDNSNLDSNNFDYSFTGNKQESNPSILNNNTNNNDNYRTS
                     SMNNNGNNYQAHSSKFGENEVIMSDHGKIYICRECNRQFSSGHHLTRHKKSVHSGEKP
                     HSCPRCGKRFKRRDHVLQHLNKKIPCTQEMENTKLAES"
     rep_origin      639867..640115
                     /note="ARS421;
                     Autonomously Replicating Sequence"
                     /db_xref="SGD:S000118437"
     gene            complement(<640109..>643837)
                     /gene="MSH6"
                     /locus_tag="YDR097C"
                     /gene_synonym="PMS3; PMS6"
                     /db_xref="GeneID:851671"
     mRNA            complement(<640109..>643837)
                     /gene="MSH6"
                     /locus_tag="YDR097C"
                     /gene_synonym="PMS3; PMS6"
                     /product="mismatch repair ATPase MSH6"
                     /transcript_id="NM_001180405.3"
                     /db_xref="GI:398365558"
                     /db_xref="GeneID:851671"
     CDS             complement(640109..643837)
                     /gene="MSH6"
                     /locus_tag="YDR097C"
                     /gene_synonym="PMS3; PMS6"
                     /note="Protein required for mismatch repair in mitosis and
                     meiosis; forms a complex with Msh2p to repair both
                     single-base & insertion-deletion mispairs; also involved
                     in interstrand cross-link repair; potentially
                     phosphorylated by Cdc28p"
                     /codon_start=1
                     /product="mismatch repair ATPase MSH6"
                     /protein_id="NP_010382.3"
                     /db_xref="GI:398365559"
                     /db_xref="SGD:S000002504"
                     /db_xref="GeneID:851671"
                     /translation="MAPATPKTSKTAHFENGSTSSQKKMKQSSLLSFFSKQVPSGTPS
                     KKVQKPTPATLENTATDKITKNPQGGKTGKLFVDVDEDNDLTIAEETVSTVRSDIMHS
                     QEPQSDTMLNSNTTEPKSTTTDEDLSSSQSRRNHKRRVNYAESDDDDSDTTFTAKRKK
                     GKVVDSESDEDEYLPDKNDGDEDDDIADDKEDIKGELAEDSGDDDDLISLAETTSKKK
                     FSYNTSHSSSPFTRNISRDNSKKKSRPNQAPSRSYNPSHSQPSATSKSSKFNKQNEER
                     YQWLVDERDAQRRPKSDPEYDPRTLYIPSSAWNKFTPFEKQYWEIKSKMWDCIVFFKK
                     GKFFELYEKDALLANALFDLKIAGGGRANMQLAGIPEMSFEYWAAQFIQMGYKVAKVD
                     QRESMLAKEMREGSKGIVKRELQCILTSGTLTDGDMLHSDLATFCLAIREEPGNFYNE
                     TQLDSSTIVQKLNTKIFGAAFIDTATGELQMLEFEDDSECTKLDTLMSQVRPMEVVME
                     RNNLSTLANKIVKFNSAPNAIFNEVKAGEEFYDCDKTYAEIISSEYFSTEEDWPEVLK
                     SYYDTGKKVGFSAFGGLLYYLKWLKLDKNLISMKNIKEYDFVKSQHSMVLDGITLQNL
                     EIFSNSFDGSDKGTLFKLFNRAITPMGKRMMKKWLMHPLLRKNDIESRLDSVDSLLQD
                     ITLREQLEITFSKLPDLERMLARIHSRTIKVKDFEKVITAFETIIELQDSLKNNDLKG
                     DVSKYISSFPEGLVEAVKSWTNAFERQKAINENIIVPQRGFDIEFDKSMDRIQELEDE
                     LMEILMTYRKQFKCSNIQYKDSGKEIYTIEIPISATKNVPSNWVQMAANKTYKRYYSD
                     EVRALARSMAEAKEIHKTLEEDLKNRLCQKFDAHYNTIWMPTIQAISNIDCLLAITRT
                     SEYLGAPSCRPTIVDEVDSKTNTQLNGFLKFKSLRHPCFNLGATTAKDFIPNDIELGK
                     EQPRLGLLTGANAAGKSTILRMACIAVIMAQMGCYVPCESAVLTPIDRIMTRLGANDN
                     IMQGKSTFFVELAETKKILDMATNRSLLVVDELGRGGSSSDGFAIAESVLHHVATHIQ
                     SLGFFATHYGTLASSFKHHPQVRPLKMSILVDEATRNVTFLYKMLEGQSEGSFGMHVA
                     SMCGISKEIIDNAQIAADNLEHTSRLVKERDLAANNLNGEVVSVPGGLQSDFVRIAYG
                     DGLKNTKLGSGEGVLNYDWNIKRNVLKSLFSIIDDLQS"
     gene            complement(<644178..>645035)
                     /gene="GRX3"
                     /locus_tag="YDR098C"
                     /db_xref="GeneID:851672"
     mRNA            complement(<644178..>645035)
                     /gene="GRX3"
                     /locus_tag="YDR098C"
                     /product="monothiol glutaredoxin GRX3"
                     /transcript_id="NM_001180406.3"
                     /db_xref="GI:398365572"
                     /db_xref="GeneID:851672"
     CDS             complement(644178..645035)
                     /gene="GRX3"
                     /locus_tag="YDR098C"
                     /note="Glutathione-dependent oxidoreductase; hydroperoxide
                     and superoxide-radical responsive; monothiol glutaredoxin
                     subfamily member along with Grx4p and Grx5p; protects
                     cells from oxidative damage; with Grx4p, binds to Aft1p in
                     iron-replete conditions, promoting its dissociation from
                     promoters; evidence exists indicating that the translation
                     start site is not Met1 as currently annotated, but rather
                     Met36; GRX3 has a paralog, GRX4, that arose from the whole
                     genome duplication"
                     /codon_start=1
                     /product="monothiol glutaredoxin GRX3"
                     /protein_id="NP_010383.3"
                     /db_xref="GI:398365573"
                     /db_xref="SGD:S000002505"
                     /db_xref="GeneID:851672"
                     /translation="MCSFQVPSAFSFNYTSYCYKRHQARYYTAAKLFQEMPVIEINDQ
                     EQFTYLTTTAAGDKLIVLYFHTSWAEPCKALKQVFEAISNEPSNSNVSFLSIDADENS
                     EISELFEISAVPYFIIIHKGTILKELSGADPKEYVSLLEDCKNSVNSGSSQTHTMENA
                     NVNEGSHNDEDDDDEEEEEETEEQINARLTKLVNAAPVMLFMKGSPSEPKCGFSRQLV
                     GILREHQVRFGFFDILRDESVRQNLKKFSEWPTFPQLYINGEFQGGLDIIKESLEEDP
                     DFLQHALQS"
     gene            complement(645153..645224)
                     /locus_tag="tQ(UUG)D2"
                     /db_xref="GeneID:851673"
     tRNA            complement(645153..645224)
                     /locus_tag="tQ(UUG)D2"
                     /product="tRNA-Gln"
                     /note="Glutamine tRNA (tRNA-Gln), predicted by tRNAscan-SE
                     analysis; thiolation of uridine at wobble position (34)
                     requires Ncs6p"
                     /db_xref="SGD:S000006694"
                     /db_xref="GeneID:851673"
     mobile_element  complement(645502..651419)
                     /note="YDRCTy1-1; Ty1 element, LTR retrotransposon of the
                     Copia (Pseudoviridae) group; contains co-transcribed genes
                     TYA Gag and TYB Pol, encoding proteins involved in
                     structure and function of virus-like particles, flanked by
                     two direct repeats"
                     /mobile_element_type="retrotransposon:YDRCTy1-1"
                     /db_xref="SGD:S000006859"
     LTR             complement(645502..645835)
                     /note="Ty1 LTR"
                     /db_xref="SGD:S000006850"
     gene            complement(<645858..>651126)
                     /locus_tag="YDR098C-B"
                     /db_xref="GeneID:851674"
     mRNA            complement(join(<645858..649820,649822..>651126))
                     /locus_tag="YDR098C-B"
                     /product="gag-pol fusion protein"
                     /transcript_id="NM_001184417.1"
                     /db_xref="GI:296143452"
                     /db_xref="GeneID:851674"
     CDS             complement(join(645858..649820,649822..651126))
                     /locus_tag="YDR098C-B"
                     /EC_number="3.4.23.-"
                     /EC_number="3.1.26.4"
                     /EC_number="2.7.7.7"
                     /EC_number="2.7.7.49"
                     /ribosomal_slippage
                     /note="Retrotransposon TYA Gag and TYB Pol genes;
                     transcribed/translated as one unit; polyprotein is
                     processed to make a nucleocapsid-like protein (Gag),
                     reverse transcriptase (RT), protease (PR), and integrase
                     (IN); similar to retroviral genes"
                     /codon_start=1
                     /product="gag-pol fusion protein"
                     /protein_id="NP_058140.1"
                     /db_xref="GI:7839152"
                     /db_xref="SGD:S000007391"
                     /db_xref="GeneID:851674"
                     /translation="MESQQLSNYPHISHGSACASVTSKEVHTNQDPLDVSASKIQEYD
                     KASTKANSQQTTTPASSAVPENPHHASPQPASVPPPQNGPYPQQCMMTQNQANPSGWS
                     FYGHPSMIPYTPYQMSPMYFPPGPQSQFPQYPSSVGTPLSTPSPESGNTFTDSSSADS
                     DMTSTKKYVRPPPMLTSPNDFPNWVKTYIKFLQNSNLGGIIPTVNGKPVRQITDDELT
                     FLYNTFQIFAPSQFLPTWVKDILSVDYTDIMKILSKSIEKMQSDTQEANDIVTLANLQ
                     YNGSTPADAFETKVTNIIDRLNNNGIHINNKVACQLIMRGLSGEYKFLRYTRHRHLNM
                     TVAELFLDIHAIYEEQQGSRNSKPNYRRNPSDEKNDSRSYTNTTKPKVIARNPQKTNN
                     SKSKTARAHNVSTSNNSPSTDNDSISKSTTEPIQLNNKHDLHLGQELTESTVNHTNHS
                     DDELPGHLLLDSGASRTLIRSAHHIHSASSNPGINVVDAQKRNIPINAIGDLQFHFQD
                     NTKTSIKVLHTPNIAYDLLSLNELAAVDITACFTKNVLERSDGTVLAPIVKYGDFYWV
                     SKKYLLPSNISVPTINNVHTSESTRKYPYPFIHRMLAHANAQTIRYSLKNNTITYFNE
                     SDVDWSSAIDYQCPDCLIGKSTKHRHIKGSRLKYQNSYEPFQYLHTDIFGPVHNLPNS
                     APSYFISFTDETTKFRWVYPLHDRREDSILDVFTTILAFIKNQFQASVLVIQMDRGSE
                     YTNRTLHKFLEKNGITPCYTTTADSRAHGVAERLNRTLLDDCRTQLQCSGLPNHLWFS
                     AIEFSTIVRNSLASPKSKKSARQHAGLAGLDISTLLPFGQPVIVNDHNPNSKIHPRGI
                     PGYALHPSRNSYGYIIYLPSLKKTVDTTNYVILQGKESRLDQFNYDALTFDEDLNRLT
                     ASYHSFIASNEIQESNDLNIESDHDFQSDIELHPEQPRNVLSKAVSPTDSTPPSTHTE
                     DSKRVSKTNIRAPREVDPNISESNILPSKKRSSTPQISNIESTGSGGMHKLNVPLLAP
                     MSQSNTHESSHASKSKDFRHSDSYSENETNHTNVPISSTGGTNNKTVPQISDQETEKR
                     IIHRSPSIDASPPENNSSHNIVPIKTPTTVSEQNTEESIIADLPLPDLPPESPTEFPD
                     PFKELPPINSHQTNSSLGGIGDSNAYTTINSKKRSLEDNETEIKVSRDTWNTKNMRSL
                     EPPRSKKRIHLIAAVKAVKSIKPIRTTLRYDEAITYNKDIKEKEKYIEAYHKEVNQLL
                     KMNTWDTDKYYDRKEIDPKRVINSMFIFNRKRDGTHKARFVARGDIQHPDTYDSGMQS
                     NTVHHYALMTSLSLALDNNYYITQLDISSAYLYADIKEELYIRPPPHLGMNDKLIRLK
                     KSLYGLKQSGANWYETIKSYLIKQCGMEEVRGWSCVFKNSQVTICLFVDDMILFSKDL
                     NANKKIITTLKKQYDTKIINLGEGDNEIQYDILGLEIKYQRSKYMKLGMEKSLTEKLP
                     KLNVPLNPKGKKLRAPGQPGHYIDQDELEIDEDEYKEKVHEMQKLIGLASYVGYKFRF
                     DLLYYINTLAQHILFPSRQVLDMTYELIQFMWDTRDKQLIWHKNKPTKPDNKLVAISD
                     ASYGNQPYYKSQIGNIFLLNGKVIGGKSTKASLTCTSTTEAEIHAVSEAIPLLNNLSH
                     LVQELNKKPIIKGSLTDSRSTISIIKSTNEEKFRNRFFGTKAMRLRDEVSGNNLYVYY
                     IETKKNIADVMTKPLPIKTFKLLTNKWIH"
     gene            complement(<649804..>651126)
                     /locus_tag="YDR098C-A"
                     /db_xref="GeneID:851675"
     mRNA            complement(<649804..>651126)
                     /locus_tag="YDR098C-A"
                     /product="gag protein"
                     /transcript_id="NM_001184416.1"
                     /db_xref="GI:296143453"
                     /db_xref="GeneID:851675"
     CDS             complement(649804..651126)
                     /locus_tag="YDR098C-A"
                     /note="Retrotransposon TYA Gag gene co-transcribed with
                     TYB Pol; translated as TYA or TYA-TYB polyprotein; Gag is
                     a nucleocapsid protein that is the structural constituent
                     of virus-like particles (VLPs); similar to retroviral Gag"
                     /codon_start=1
                     /product="gag protein"
                     /protein_id="NP_058141.1"
                     /db_xref="GI:7839151"
                     /db_xref="SGD:S000007390"
                     /db_xref="GeneID:851675"
                     /translation="MESQQLSNYPHISHGSACASVTSKEVHTNQDPLDVSASKIQEYD
                     KASTKANSQQTTTPASSAVPENPHHASPQPASVPPPQNGPYPQQCMMTQNQANPSGWS
                     FYGHPSMIPYTPYQMSPMYFPPGPQSQFPQYPSSVGTPLSTPSPESGNTFTDSSSADS
                     DMTSTKKYVRPPPMLTSPNDFPNWVKTYIKFLQNSNLGGIIPTVNGKPVRQITDDELT
                     FLYNTFQIFAPSQFLPTWVKDILSVDYTDIMKILSKSIEKMQSDTQEANDIVTLANLQ
                     YNGSTPADAFETKVTNIIDRLNNNGIHINNKVACQLIMRGLSGEYKFLRYTRHRHLNM
                     TVAELFLDIHAIYEEQQGSRNSKPNYRRNPSDEKNDSRSYTNTTKPKVIARNPQKTNN
                     SKSKTARAHNVSTSNNSPSTDNDSISKSTTEPIQLNNKHDLHLRPGTY"
     LTR             complement(651086..651419)
                     /note="Ty1 LTR"
                     /db_xref="SGD:S000006851"
     LTR             complement(651420..651503)
                     /note="Ty3 LTR"
                     /db_xref="SGD:S000006855"
     LTR             complement(651682..651980)
                     /note="Ty1 LTR"
                     /db_xref="SGD:S000006852"
     gene            <653607..>654428
                     /gene="BMH2"
                     /locus_tag="YDR099W"
                     /gene_synonym="SCD3"
                     /db_xref="GeneID:851676"
     mRNA            <653607..>654428
                     /gene="BMH2"
                     /locus_tag="YDR099W"
                     /gene_synonym="SCD3"
                     /product="14-3-3 family protein BMH2"
                     /transcript_id="NM_001180407.3"
                     /db_xref="GI:398365596"
                     /db_xref="GeneID:851676"
     CDS             653607..654428
                     /gene="BMH2"
                     /locus_tag="YDR099W"
                     /gene_synonym="SCD3"
                     /note="14-3-3 protein, minor isoform; controls proteome at
                     post-transcriptional level, binds proteins and DNA,
                     involved in regulation of many processes including
                     exocytosis, vesicle transport, Ras/MAPK signaling, and
                     rapamycin-sensitive signaling; protein increases in
                     abundance and relative distribution to the nucleus
                     increases upon DNA replication stress; BMH2 has a paralog,
                     BMH1, that arose from the whole genome duplication"
                     /codon_start=1
                     /product="14-3-3 family protein BMH2"
                     /protein_id="NP_010384.3"
                     /db_xref="GI:398365597"
                     /db_xref="SGD:S000002506"
                     /db_xref="GeneID:851676"
                     /translation="MSQTREDSVYLAKLAEQAERYEEMVENMKAVASSGQELSVEERN
                     LLSVAYKNVIGARRASWRIVSSIEQKEESKEKSEHQVELIRSYRSKIETELTKISDDI
                     LSVLDSHLIPSATTGESKVFYYKMKGDYHRYLAEFSSGDAREKATNSSLEAYKTASEI
                     ATTELPPTHPIRLGLALNFSVFYYEIQNSPDKACHLAKQAFDDAIAELDTLSEESYKD
                     STLIMQLLRDNLTLWTSDISESGQEDQQQQQQQQQQQQQQQQQAPAEQTQGEPTK"
     gene            <655013..>655444
                     /gene="TVP15"
                     /locus_tag="YDR100W"
                     /db_xref="GeneID:851677"
     mRNA            <655013..>655444
                     /gene="TVP15"
                     /locus_tag="YDR100W"
                     /product="Tvp15p"
                     /transcript_id="NM_001180408.3"
                     /db_xref="GI:398365600"
                     /db_xref="GeneID:851677"
     CDS             655013..655444
                     /gene="TVP15"
                     /locus_tag="YDR100W"
                     /note="Integral membrane protein; localized to late Golgi
                     vesicles along with the v-SNARE Tlg2p"
                     /codon_start=1
                     /product="Tvp15p"
                     /protein_id="NP_010385.3"
                     /db_xref="GI:398365601"
                     /db_xref="SGD:S000002507"
                     /db_xref="GeneID:851677"
                     /translation="MSVIPPKFFKIANISIGCIDIIAALSQLTYIFTNLNVFLLAVYG
                     LALSVPIVYLEFKVPSNLYRYASFYFSFLGRGLSYILLSLIISFGGIYNILAGMFTFI
                     LGVAFIVFHFSQFVEEPANFRAPGSSLSIGDDDIDDDDDMI"
     gene            complement(<655686..>657467)
                     /gene="ARX1"
                     /locus_tag="YDR101C"
                     /db_xref="GeneID:851678"
     mRNA            complement(<655686..>657467)
                     /gene="ARX1"
                     /locus_tag="YDR101C"
                     /product="Arx1p"
                     /transcript_id="NM_001180409.1"
                     /db_xref="GI:296143456"
                     /db_xref="GeneID:851678"
     CDS             complement(655686..657467)
                     /gene="ARX1"
                     /locus_tag="YDR101C"
                     /EC_number="3.-.-.-"
                     /note="Nuclear export factor for the ribosomal pre-60S
                     subunit; shuttling factor which directly binds FG rich
                     nucleoporins and facilities translocation through the
                     nuclear pore complex; interacts directly with Alb1p;
                     responsible for Tif6p recycling defects in the absence of
                     Rei1; associated with the ribosomal export complex"
                     /codon_start=1
                     /product="Arx1p"
                     /protein_id="NP_010386.1"
                     /db_xref="GI:6320306"
                     /db_xref="SGD:S000002508"
                     /db_xref="GeneID:851678"
                     /translation="MALAISHEDTQILLKDKNILQESVLNKYRTAGQIAQTALKYVTS
                     LINDSYHSKTTQRQLTVPELCLLTDSFILTRLEQYYKNKVNERGIAIPTTIDIDQISG
                     GWCPEIDDTQNLLNWNKGKDSTFASSVTGTLRPGDLVKITLGVHIDGYTSEVSHTMVI
                     YPVDETKPILQPTGPLLGGKADAVAAAHIAMETVVALLACALTPEKLPASLGGTSSGI
                     TGQLIRTIVDTIARSYNCGVVPGSRVRRIRRFLAGQNEGIVAEREYKGVVWTESHQEA
                     DLLSNTDAKDLTVVDRGQSTPFTNVSAIPSDDFVVQSGEVYLIDLKMASLEHCTKKGL
                     VTLETVDSYTGKSHKAGELIARPGAYVRDFAQTHILKLKTSRQLLTKIDKQGVYPFKL
                     SHLSSNFPFVHENEEELQSLKKDLKSFRLGMSEISNNYLCVESPIQIARWVPWDHILK
                     ATNPNGNLSYDATSTLTLPGHELPLPKLGVSAIKLKSLMNSTKESISLPVARECNTIV
                     LCDSSVSTTDRPELLRLTGGSKTCQPSWIHSQHELNPQDSIVQGIFQLATLAKDKRFG
                     LLLKETQPMKQKSVETSNGGVEETMKM"
     gene            <658350..>661103
                     /gene="STE5"
                     /locus_tag="YDR103W"
                     /gene_synonym="HMD3; NUL3"
                     /db_xref="GeneID:851680"
     mRNA            <658350..>661103
                     /gene="STE5"
                     /locus_tag="YDR103W"
                     /gene_synonym="HMD3; NUL3"
                     /product="Ste5p"
                     /transcript_id="NM_001180411.1"
                     /db_xref="GI:296143457"
                     /db_xref="GeneID:851680"
     CDS             658350..661103
                     /gene="STE5"
                     /locus_tag="YDR103W"
                     /gene_synonym="HMD3; NUL3"
                     /note="Pheromone-responsive MAPK scaffold protein; couples
                     activation of the G-protein-coupled pheromone receptor to
                     MAPK activation; intramolecular interaction of PH and VWA
                     domains blocks activation of assembled signaling cascade
                     components (Ste11p, Ste7p and Fus3p) under basal
                     conditions; Gbeta-gamma (Ste4p-Ste18p)-dependent docking
                     at the plasma membrane and binding of PI(4,5)P2 by the PH
                     domain relieves autoinhibition, resulting in
                     pheromone-dependent pathway activation"
                     /codon_start=1
                     /product="Ste5p"
                     /protein_id="NP_010388.1"
                     /db_xref="GI:6320308"
                     /db_xref="SGD:S000002510"
                     /db_xref="GeneID:851680"
                     /translation="MMETPTDNIVSPFHNFGSSTQYSGTLSRTPNQIIELEKPSTLSP
                     LSRGKKWTEKLARFQRSSAKKKRFSPSPISSSTFSFSPKSRVTSSNSSGNEDGNLMNT
                     PSTVSTDYLPQHPHRTSSLPRPNSNLFHASNSNLSRANEPPRAENLSDNIPPKVAPFG
                     YPIQRTSIKKSFLNASCTLCDEPISNRRKGEKIIELACGHLSHQECLIISFGTTSKAD
                     VRALFPFCTKCKKDTNKAVQCIPENDELKDILISDFLIHKIPDSELSITPQSRFPPYS
                     PLLPPFGLSYTPVERQTIYSQAPSLNPNLILAAPPKERNQIPQKKSNYTFLHSPLGHR
                     RIPSGANSILADTSVALSANDSISAVSNSVRAKDDETKTTLPLLRSYFIQILLNNFQE
                     ELQDWRIDGDYGLLRLVDKLMISKDGQRYIQCWCFLFEDAFVIAEVDNDVDVLEIRLK
                     NLEVFTPIANLRMTTLEASVLKCTLNKQHCADLSDLYIVQNINSDESTTVQKWISGIL
                     NQDFVFNEDNITSTLPILPIIKNFSKDVGNGRHETSTFLGLINPNKVVEVGNVHDNDT
                     VIIRRGFTLNSGECSRQSTVDSIQSVLTTISSILSLKREKPDNLAIILQIDFTKLKEE
                     DSLIVVYNSLKALTIKFARLQFCFVDRNNYVLDYGSVLHKIDSLDSISNLKSKSSSTQ
                     FSPIWLKNTLYPENIHEHLGIVAVSNSNMEAKKSILFQDYRCFTSFGRRRPNELKIKV
                     GYLNVDYSDKIDELVEASSWTFVLETLCYSFGLSFDEHDDDDEEDNDDSTDNELDNSS
                     GSLSDAESTTTIHIDSPFDNENATANMVNDRNLLTEGEHSNIENLETVASSVQPALIP
                     NIRFSLHSEEEGTNENENENDMPVLLLSDMDKGIDGITRRSSFSSLIESGNNNCPLHM
                     DYI"
     gene            complement(<661173..>664910)
                     /gene="SPO71"
                     /locus_tag="YDR104C"
                     /db_xref="GeneID:851681"
     mRNA            complement(<661173..>664910)
                     /gene="SPO71"
                     /locus_tag="YDR104C"
                     /product="Spo71p"
                     /transcript_id="NM_001180412.3"
                     /db_xref="GI:398365612"
                     /db_xref="GeneID:851681"
     CDS             complement(661173..664910)
                     /gene="SPO71"
                     /locus_tag="YDR104C"
                     /note="Meiosis-specific protein required for spore wall
                     formation; localizes to prospore membrane (PSM) and is
                     required for PSM closure during sporulation; mediates PSM
                     size; interacts with Spo1p and Vps13p and recruits Vps13p
                     to the PSM during sporulation; mutants exhibit reduction
                     in PSM PtdIns-phosphate pools; dispensable for both
                     nuclear divisions during meiosis; contains two PH domains"
                     /codon_start=1
                     /product="Spo71p"
                     /protein_id="NP_010389.3"
                     /db_xref="GI:398365613"
                     /db_xref="SGD:S000002511"
                     /db_xref="GeneID:851681"
                     /translation="MDSIVNVVEDDVKYAQRVTSFSSPQNANVKVFTIPRHSFTAFRL
                     SYVSPTELSACSQVTLLGGIPKQWYADQNNQVWKLLTKISLRKVRKQSDMLRRYGYGT
                     IYKKRVGKIPTALYLRKHFTWSYEDNTSIHNGHRLKEAEMEMKRTRSSPVQKSEYKLS
                     LPRRCRSSSDQNFMRQELLKEKKSELSRNNSLPLIDTAQAVDIHPVLHEEDQENTNKR
                     NKSLLSNLKRKDLGESKSISRKDYSHFDRIPSPSSARSVGETDFNYNREPSEDTLRYP
                     DSIIEVTNRTSPAPNSILSRSGQFVNSNDLSDGFSTSNTINNVGLNANEKIFFNALQS
                     MEKENLMLWKTSQKYGTYLDERRKSADAFQKRERGSCVDIGKLHSSHLPFINILPPWP
                     TELTEEERIIHDRLASKHSHHIRKHVHNARNKTSCKIKDSVGTFLGMTNSLTNKATVK
                     KRTGQILKKEKMLVMVKEAIQNKVPLPNFSENECFDTRVSERWKEYIVIARSTGRFDP
                     PILLQFYRHRHIPEIEDISSIATKYHRNPLDFFLSRNCIVKFYSSLDKTISIQKPDKR
                     LGGFIDESIEKKDELKHYSPIKIFILRCSSIRSSGRWYKFLLESLDRQLFTPAINLKI
                     PLTEISIKINLNEIIFQKLIDLGKQEKDRLKICFLQRGYKIFQHPILRYFTVAILEKL
                     KLAHYDYLIRKWDTENPVLGCALKRYDRLEWIPCDEDSLVTGIFAFCQSHLIQYRPIA
                     NRLRETKSLEGKCLKEPTPIEGFLIRLTDKYGSARTNFGKYSISTAYFFTCENLLFSM
                     KAYRANPPLPIDSMIDDTSTEIEKEEIWKQWKKIPEVYEQQPYPLDTNDHIEWMNCQT
                     TQSEYDSRDFYAFHCFHRRIDQILKTDNVIDLTEVKDIYQGTRTDYEADKIKYGVYKE
                     ASEIFWHRNYEIDDVSRSVINIETSNGLLLKLLATSATVAEEWVIKLKQMISYWKNKQ
                     REDTERLLKIRRSNAGLLMLNGEEETKIGENTLRWIVEHGRADEQTFNANGISLSRPL
                     IQKGPLYQKPHKHSVFSKYYVVLISGFIVLFHCFHRSTTGFAKEVLEYAHYVTIPIDD
                     CYLYSGTTTELDLLQRDRTFDEINYGSHALPRVYGDGWRSVEDESSRCFTLWFGTRRA
                     LSSNRLQKKGNEKQYTQDYGRQDNNIDPPSAPEADLNNSNVPSNTDKIHFTKKLGVSG
                     KSMVFMARSRQERDLWVMSIYYELERLRRTASTSNSRNQTM"
     gene            complement(<665349..>666770)
                     /gene="TMS1"
                     /locus_tag="YDR105C"
                     /db_xref="GeneID:851682"
     mRNA            complement(<665349..>666770)
                     /gene="TMS1"
                     /locus_tag="YDR105C"
                     /product="Tms1p"
                     /transcript_id="NM_001180413.3"
                     /db_xref="GI:398365622"
                     /db_xref="GeneID:851682"
     CDS             complement(665349..666770)
                     /gene="TMS1"
                     /locus_tag="YDR105C"
                     /note="Vacuolar membrane hypothetical protein; is
                     conserved in mammals; predicted to contain eleven
                     transmembrane helices; interacts with Pdr5p, a protein
                     involved in multidrug resistance"
                     /codon_start=1
                     /product="Tms1p"
                     /protein_id="NP_010390.3"
                     /db_xref="GI:398365623"
                     /db_xref="SGD:S000002512"
                     /db_xref="GeneID:851682"
                     /translation="MGAVISLPVSMAGSFVASCFGGCCSNLVTKTASSLGSSSLGTRL
                     LYAVWLLLNSLISWVSYSANKSILWPGKTCTGTGECGFFTVHRLNFALGCLHLILALV
                     LTGVKSTNDVRAALQNSWWSLKFILYLCLIVLSFVIPNDFYIFFSKWVSVPSGAIFIL
                     VGLILLVDFAHEWAETCISHVESEDEDSSFWQRFLVLGTTSMYTASIIMTVVMYVMFC
                     HQQCNMNQTAVTVNLILTVITLVLSVNPKIQEANPKSGLAQSSMVSVYCTYLTMSAMS
                     SEPDDKMCNPLVRSSGTRKFSIILGSLFTFIAIAYTTTRAAANSAFQGTNTNGAIYLG
                     NDIEYEGLGGQTRNQLRYEAIKQAVEEGSLPESALYDTAWLGTSSPTGAMDNQNDDER
                     TGTKYNYTLFHVIFFLATQWIAILLTINVTQDDVGDFIPVGRTYFYSWVKIVSAWICY
                     ALYGWTVVAPAIMPDRFDYENYY"
     gene            <667004..>667858
                     /gene="ARP10"
                     /locus_tag="YDR106W"
                     /db_xref="GeneID:851683"
     mRNA            <667004..>667858
                     /gene="ARP10"
                     /locus_tag="YDR106W"
                     /product="Arp10p"
                     /transcript_id="NM_001180414.1"
                     /db_xref="GI:296143460"
                     /db_xref="GeneID:851683"
     CDS             667004..667858
                     /gene="ARP10"
                     /locus_tag="YDR106W"
                     /note="Component of the dynactin complex; localized to the
                     pointed end of the Arp1p filament; may regulate membrane
                     association of the complex"
                     /codon_start=1
                     /product="Arp10p"
                     /protein_id="NP_010391.1"
                     /db_xref="GI:6320311"
                     /db_xref="SGD:S000002513"
                     /db_xref="GeneID:851683"
                     /translation="MSNTIVIVYLGANRIEIGRSADACPQEIIAWKTGSINEKNREEL
                     KKIFEHYFQICNILGNREVQVLILEDIFISVVEKRIICSILFKEFDCAHVSFVPRAIV
                     HCLSCNTRNAIVIDIGTNYTTCVPIFDLRPLQQFIKYSKRGKRQVESRIPLPGSLYMP
                     IFFDEEYNSKNCEVDETPVINLVKNIVESLPIDLRRPLRENIIIVNIEEAYETVIRNL
                     FKLKMDTSKIQFPKNYWQAGSACAKILLHYKGSNIVGIERDEFYNNPHIAPDWFDYYF
                     RTGVKRLQ"
     gene            complement(668007..668080)
                     /locus_tag="tI(AAU)D"
                     /db_xref="GeneID:851684"
     tRNA            complement(668007..668080)
                     /locus_tag="tI(AAU)D"
                     /product="tRNA-Ile"
                     /note="Isoleucine tRNA (tRNA-Ile), predicted by
                     tRNAscan-SE analysis"
                     /db_xref="SGD:S000006601"
                     /db_xref="GeneID:851684"
     LTR             668096..668436
                     /note="Ty3 LTR"
                     /db_xref="SGD:S000006856"
     LTR             668543..668784
                     /note="Ty1 LTR"
                     /db_xref="SGD:S000006864"
     gene            complement(<669016..>671034)
                     /gene="TMN2"
                     /locus_tag="YDR107C"
                     /db_xref="GeneID:851685"
     mRNA            complement(<669016..>671034)
                     /gene="TMN2"
                     /locus_tag="YDR107C"
                     /product="Tmn2p"
                     /transcript_id="NM_001180415.1"
                     /db_xref="GI:296143461"
                     /db_xref="GeneID:851685"
     CDS             complement(669016..671034)
                     /gene="TMN2"
                     /locus_tag="YDR107C"
                     /note="Protein with a role in cellular adhesion and
                     filamentous growth; similar to Tmn3p; member of the
                     evolutionarily conserved Transmembrane Nine family of
                     proteins with nine membrane-spanning segments; TMN2 has a
                     paralog, EMP70, that arose from the whole genome
                     duplication"
                     /codon_start=1
                     /product="Tmn2p"
                     /protein_id="NP_010392.1"
                     /db_xref="GI:6320312"
                     /db_xref="SGD:S000002514"
                     /db_xref="GeneID:851685"
                     /translation="MKRGVWLLIYCYATLTKGFSLPGLSPTTYHSGDEIPLLVNRLTP
                     SIYFQHQDEEGNDVSGDKEHFLYSYDYYNKRFHFCRPEHVEKQPESLGSVIFGDRIYN
                     SPFQLNMLEEKECVALCKSTIPGKDAKFINTLIKSGFFQNWLVDGLPAARKAYDSRTK
                     TNYYGTGFELGFTDVKQTVDGKAVPSTMEELTSEASNEDVILDARLPKNVKPNLVKTV
                     ELPYFVNHFDIEVEFHDRGNDNYRVVGVIVNPVSIERSSPGACSTTGKPLILDEDKDN
                     EVYFTYSVKFVASDTVWATRWDKYLHIYDPQIQWFSLINFSVIVILLSSVVMHSLLRA
                     LKSDLARYNELNLDNEFHEDSGWKLGHGDVFRTPSKSMLLSILVGSGMQLFLMVMCSI
                     FFAAVGLVSPVSRGSLPTVMFVLYALFGFVGSYASMGVYKFFRGPYWKANMILTPILL
                     PGAIFLLIVIMNFFLLFAHSSGVIPARSLFFIILLWFLVSVPLSFAGSIVAHKQCNWD
                     EHPTKTNQIARQIPYQPWYLRTAQATLIAGIFSFGSIAVELYFIYSSLWFNKIFYMFG
                     FLLFSFLLLTLTTSLVTILITYYSLCLENWLWQWRSFIIGGLGCSIYTFIHSILFTKF
                     KLGGVITVVLYLGYSLIISALCCVVTGAIGFFSSMFFIRKIYSAIKVE"
     gene            <671269..>673365
                     /gene="TRS85"
                     /locus_tag="YDR108W"
                     /gene_synonym="GSG1; MUM1"
                     /db_xref="GeneID:851686"
     mRNA            <671269..>673365
                     /gene="TRS85"
                     /locus_tag="YDR108W"
                     /gene_synonym="GSG1; MUM1"
                     /product="Trs85p"
                     /transcript_id="NM_001180416.3"
                     /db_xref="GI:398365642"
                     /db_xref="GeneID:851686"
     CDS             671269..673365
                     /gene="TRS85"
                     /locus_tag="YDR108W"
                     /gene_synonym="GSG1; MUM1"
                     /note="Component of transport protein particle (TRAPP)
                     complex III; TRAPPIII is a multimeric guanine
                     nucleotide-exchange factor for the GTPase Ypt1p,
                     regulating endosome-Golgi traffic and required for
                     membrane expansion during autophagy and the CVT pathway;
                     directs Ypt1p to the PAS; late post-replication meiotic
                     role"
                     /codon_start=1
                     /product="Trs85p"
                     /protein_id="NP_010393.3"
                     /db_xref="GI:398365643"
                     /db_xref="SGD:S000002515"
                     /db_xref="GeneID:851686"
                     /translation="MVFSYEHYMNLLFHLDNSKETVPPEIAKRIISNAIAPVITVTST
                     PLFDKHIQETYKVDSLYMLLRFFGGCVSDRDQANEAKVGQHEHEVCDASDSTDSIPKN
                     KNLEVPNLSKKGSRSRSNSLFQRDSTQSQYIRFTRPLGDLIETRDANDMLFNYHSLEV
                     FLDNYLKLVAANTDEMVPHNLLKKSIYHSFFSLAISSTNNLSPYETFNHPILSLIALD
                     ISNGEVYEDARDLLVNFKNLNHNTENFPIFMNTNEMLPVFLLCYNDDSQEEFEKCQAL
                     AKKLKKQLFVESILLALWKDSFIYDENSVIQLHQPVMSSLEEILFFLQAPTQTTLSLA
                     LINSIYDMLDYLVYDLMIPFMKRKVSFWEETILQPRKSLFNGAKFFKKFMNKNPVNGN
                     HQHNSLTRDSQGNEYFASSSSEFLMRKLADWSMMLSDFKTAYSTYESLMDDLDAFPKY
                     LASCIEWCAVSLLMGAQSIVTVKMIKNDINPLIERALATYENCSRIQRGKGKESNSLD
                     VTEPVRSYETRCMILASELFLSLSNTWTSTPYAIQYLETILDECKLGPCSQIMVWERL
                     SDCYNLRVDPRIKHRVGAMKKDAKDTEDLRGEHKYSTDHFTDEDILSEGLTRRRKAAF
                     FRLIAAKKWAEQKQWRQVSWCLKDIESTYSEIKFLHGNGLILSKLKNQLNLKDVDSAP
                     RPSEKNLTRTSVSFIG"
     gene            complement(<673520..>675667)
                     /locus_tag="YDR109C"
                     /db_xref="GeneID:851687"
     mRNA            complement(<673520..>675667)
                     /locus_tag="YDR109C"
                     /product="putative phosphotransferase"
                     /transcript_id="NM_001180417.3"
                     /db_xref="GI:398365648"
                     /db_xref="GeneID:851687"
     CDS             complement(673520..675667)
                     /locus_tag="YDR109C"
                     /EC_number="2.7.1.-"
                     /note="Putative kinase"
                     /codon_start=1
                     /product="putative phosphotransferase"
                     /protein_id="NP_010394.3"
                     /db_xref="GI:398365649"
                     /db_xref="SGD:S000002516"
                     /db_xref="GeneID:851687"
                     /translation="MKSRKRQNNMQNETREPAVLSSQETSISRISPQDPEAKFYVGVD
                     VGTGSARACVIDQSGNMLSLAEKPIKREQLISNFITQSSREIWNAVCYCVRTVVEESG
                     VDPERVRGIGFDATCSLVVVSATNFEEIAVGPDFTNNDQNIILWMDHRAMKETEEINS
                     SGDKCLKYVGGQMSVEMEIPKIKWLKNNLEAGIFQDCKFFDLPDYLTFKATGKENRSF
                     CSAVCKQGFLPVGVEGSDIGWSKEFLNSIGLSELTKNDFERLGGSLREKKNFLTAGEC
                     ISPLDKKAACQLGLTEHCVVSSGIIDAYAGWVGTVAAKPESAVKGLAETENYKKDFNG
                     AIGRLAAVAGTSTCHILLSKNPIFVHGVWGPYRDVLARGFWAAEGGQSCTGVLLDHLI
                     TTHPAFTELSHMANLAGVSKFEYLNKILETLVEKRKVRSVISLAKHLFFYGDYHGNRS
                     PIADPNMRACIIGQSMDNSIEDLAVMYLSACEFISQQTRQIIEVMLKSGHEINAIFMS
                     GGQCRNSLLMRLLADCTGLPIVIPRYVDAAVVFGSALLGAAASEDFDYTREKRTLKGQ
                     KSSQTKTERFNDSYSSIQKLSMEDRNSTNGFVSPHNLQLSTPSAPAKINNYSLPICTQ
                     QPLDKTSEESSKDASLTVGQESLGEGRYNGTSFLWKVMQELTGNARIVNPNEKTHPDR
                     ILLDTKYQIFLDMIETQRKYRRMVDKVEGSFSR"
     gene            <676102..>677802
                     /gene="FOB1"
                     /locus_tag="YDR110W"
                     /gene_synonym="HRM1"
                     /db_xref="GeneID:851688"
     mRNA            <676102..>677802
                     /gene="FOB1"
                     /locus_tag="YDR110W"
                     /gene_synonym="HRM1"
                     /product="Fob1p"
                     /transcript_id="NM_001180418.1"
                     /db_xref="GI:296143464"
                     /db_xref="GeneID:851688"
     CDS             676102..677802
                     /gene="FOB1"
                     /locus_tag="YDR110W"
                     /gene_synonym="HRM1"
                     /note="Nucleolar protein that binds the rDNA replication
                     fork barrier site; required for replication fork blocking,
                     recombinational hotspot activity, condensin recruitment to
                     replication fork barrier (RFB), and rDNA repeat
                     segregation; related to retroviral integrases"
                     /codon_start=1
                     /product="Fob1p"
                     /protein_id="NP_010395.1"
                     /db_xref="GI:6320315"
                     /db_xref="SGD:S000002517"
                     /db_xref="GeneID:851688"
                     /translation="MTKPRYNDVLFDDDDSVPSESVTRKSQRRKATSPGESRESSKDR
                     LLILPSMGESYTEYVDSYLNLELLERGERETPIFLESLTRQLTQKIYELIKTKSLTAD
                     TLQQISDKYDGVVAENKLLFLQRQYYVDDEGNVRDGRNNDKIYCEPKHVYDMVMATHL
                     MNKHLRGKTLHSFLFSHFANISHAIIDWVQQFCSKCNKKGKIKPLKEYKRPDMYDKLL
                     PMERIHIEVFEPFNGEAIEGKYSYVLLCRDYRSSFMWLLPLKSTKFKHLIPVVSSLFL
                     TFARVPIFVTSSTLDKDDLYDICEEIASKYGLRIGLGLKSSARFHTGGILCIQYALNS
                     YKKECLADWGKCLRYGPYRFNRRRNKRTKRKPVQVLLSEVPGHNAKFETKRERVIENT
                     YSRNMFKMAGGKGLIYLEDVNTFALANEADNSCNNNGILHNNNIGNDNFEEEVQKQFD
                     LTEKNYIDEYDDLAHDSSEGEFEPNTLTPEEKPPHNVDEDRIESTGVAAPMQGTEEPE
                     KGDQKESDGASQVDQSVEITRPETSYYQTLESPSTKRQKLDQQGNGDQTRDFGTSMEL
                     "
     gene            complement(<678241..>679764)
                     /gene="ALT2"
                     /locus_tag="YDR111C"
                     /db_xref="GeneID:851690"
     mRNA            complement(<678241..>679764)
                     /gene="ALT2"
                     /locus_tag="YDR111C"
                     /product="alanine transaminase ALT2"
                     /transcript_id="NM_001180419.1"
                     /db_xref="GI:296143465"
                     /db_xref="GeneID:851690"
     CDS             complement(678241..679764)
                     /gene="ALT2"
                     /locus_tag="YDR111C"
                     /EC_number="2.6.1.2"
                     /note="Catalytically inactive alanine transaminase;
                     expression is repressed in the presence of alanine and
                     repression is mediated by Nrg1p; ALT2 has a paralog, ALT1,
                     that arose from the whole genome duplication"
                     /codon_start=1
                     /product="alanine transaminase ALT2"
                     /protein_id="NP_010396.1"
                     /db_xref="GI:6320317"
                     /db_xref="SGD:S000002518"
                     /db_xref="GeneID:851690"
                     /translation="MTMTHQQDLKGVFTAKDLDFKPAGKITKKDLNTGVTKAEYAVRG
                     AIPTRADELKEELKKNPEVLPFDDIINANIGNPQQLDQKPLTFTRQVLAILEYPEILR
                     VGHNELASLNLFSRDALERAERLLNDIGGSIGAYSHSQGVPGIRQTVADFITRRDGGE
                     PATPEDIYLTTGASSAATSLLSLLCKDSQTGLLIPIPQYPLYTASASLFNAQVLPYYL
                     DEESNWSTNSDEIEKVVQDALKKQIRPSVLIVINPGNPTGAVLSEETIARICLIAAKY
                     GITIISDEVYQENIFNDVKFHSMKKVLRKLQHLYPGKFDNVQLASLHSISKGFMDECG
                     QRGGYMEIIGFSQEIRDALFKLMSISICSVVTGQAVVDLMVKPPQPGDESYEQDHDER
                     LKIFHEMRTRANLLYETFKELEGIECQKPQGAMYLFPRLVLPKKALCESERLGIEPDE
                     FYCTSLLESTGICTVPGSGFGQRPGTYHVRTTFLAPGTKWIQDWKEFHQDFFSKYRN"
     gene            complement(<680496..>681617)
                     /gene="PDS1"
                     /locus_tag="YDR113C"
                     /db_xref="GeneID:851691"
     mRNA            complement(<680496..>681617)
                     /gene="PDS1"
                     /locus_tag="YDR113C"
                     /product="Pds1p"
                     /transcript_id="NM_001180421.3"
                     /db_xref="GI:398365666"
                     /db_xref="GeneID:851691"
     CDS             complement(680496..681617)
                     /gene="PDS1"
                     /locus_tag="YDR113C"
                     /note="Securin; inhibits anaphase by binding separin
                     Esp1p; blocks cyclin destruction and mitotic exit,
                     essential for meiotic progression and mitotic cell cycle
                     arrest; localization is cell-cycle dependent and regulated
                     by Cdc28p phosphorylation"
                     /codon_start=1
                     /product="Pds1p"
                     /protein_id="NP_010398.3"
                     /db_xref="GI:398365667"
                     /db_xref="SGD:S000002520"
                     /db_xref="GeneID:851691"
                     /translation="MMPANEDKENNIVYTGNESSGINFPQTPAHLLKRSHSNILKPPV
                     RLDQLKRDANSNNGNTLKYIQGGKEVSPTKRLHTHAQQQGRLPLAAKDNNRSKSFIFP
                     ETSNQSKDADLPQLQNTLSIRKNDQLRKLSQISRSRSRANHNDLLSNSRKLQKYGSVL
                     GYNALPKMKSLVLKDLADSGKNEESSDDDEGNEDSESKLGKKLQSALLKQDSSDGENE
                     LNGGLGLFNEQGGLQQLIKNSTKNEQKTKNDKSDKTDDYDIEIAPQRQEPLPYVPEGY
                     SPFQQDDIEKLKTFNSPYKLDLEDEDDTPDKVDLLPLEQIDEEGEKDETECITRNQEE
                     GAALPLLSKNFKEVAAVPTMELVYSEEGLDPEELEDLVT"
     gene            complement(<681924..>682226)
                     /locus_tag="YDR114C"
                     /db_xref="GeneID:851693"
     mRNA            complement(<681924..>682226)
                     /locus_tag="YDR114C"
                     /product="hypothetical protein"
                     /transcript_id="NM_001180422.3"
                     /db_xref="GI:398365672"
                     /db_xref="GeneID:851693"
     CDS             complement(681924..682226)
                     /locus_tag="YDR114C"
                     /note="hypothetical protein; deletion mutant exhibits poor
                     growth at elevated pH and calcium"
                     /codon_start=1
                     /product="hypothetical protein"
                     /protein_id="NP_010399.3"
                     /db_xref="GI:398365673"
                     /db_xref="SGD:S000002521"
                     /db_xref="GeneID:851693"
                     /translation="MKTFFLIEAGRALQIVAFRPAITTVLFQRFSVSFSCSYFTCCTS
                     QLLRENWLFKFLTAFDHVIRASNDLSTMRFMIMYIYVYIYIYTVLRKRLSCYMLIL"
     gene            <682175..>682492
                     /locus_tag="YDR115W"
                     /db_xref="GeneID:851692"
     mRNA            <682175..>682492
                     /locus_tag="YDR115W"
                     /product="putative mitochondrial 54S ribosomal protein"
                     /transcript_id="NM_001180423.1"
                     /db_xref="GI:296143468"
                     /db_xref="GeneID:851692"
     CDS             682175..682492
                     /locus_tag="YDR115W"
                     /note="Putative mitochondrial ribosomal protein of the
                     large subunit; similar to E. coli L34 ribosomal protein;
                     required for respiratory growth, as are most mitochondrial
                     ribosomal proteins; protein increases in abundance and
                     relocalizes to the plasma membrane upon DNA replication
                     stress"
                     /codon_start=1
                     /product="putative mitochondrial 54S ribosomal protein"
                     /protein_id="NP_010400.1"
                     /db_xref="GI:6320319"
                     /db_xref="SGD:S000002522"
                     /db_xref="GeneID:851692"
                     /translation="MPLFARLCQPQSRRMFSSISSFSALSVLRPQTGMLLNSSPLKTP
                     SFTPLGFGLIGQRRWKSRGNTYQPSTLKRKRTFGFLARAKSKQGSKILKRRKLKGRWF
                     LSH"
     gene            complement(<682724..>683581)
                     /gene="MRPL1"
                     /locus_tag="YDR116C"
                     /db_xref="GeneID:851694"
     mRNA            complement(<682724..>683581)
                     /gene="MRPL1"
                     /locus_tag="YDR116C"
                     /product="mitochondrial 54S ribosomal protein MRPL1"
                     /transcript_id="NM_001180424.1"
                     /db_xref="GI:296143469"
                     /db_xref="GeneID:851694"
     CDS             complement(682724..683581)
                     /gene="MRPL1"
                     /locus_tag="YDR116C"
                     /note="Mitochondrial ribosomal protein of the large
                     subunit"
                     /codon_start=1
                     /product="mitochondrial 54S ribosomal protein MRPL1"
                     /protein_id="NP_010401.1"
                     /db_xref="GI:6320321"
                     /db_xref="SGD:S000002523"
                     /db_xref="GeneID:851694"
                     /translation="MLSVVAIPKICVTGPARRCFFHTAKKLYADDYKPAAMSSNAPSL
                     TKDQAKKRELKRLVQRKAEAKRPATASPLYMPVTKALRYLRAAEVGRPQSQQTINLTT
                     LVVGERGTAPLSGSVTFPKPLRYIKIAAFTNDESKLEELREKYPNHLIGGADLVAKIK
                     SGEISVDFDKAFATPDIVPALQSQVARILGPRGVLPSVKKGTVSDDISSLLQESLGSM
                     PFRQRGNSISIGVGKCYFTDREILQNIISARAAFKTAVDNQKSKKPNILSKTTLSSTH
                     GPGIVIDFA"
     gene            complement(<683946..>685643)
                     /gene="TMA64"
                     /locus_tag="YDR117C"
                     /db_xref="GeneID:851695"
     mRNA            complement(<683946..>685643)
                     /gene="TMA64"
                     /locus_tag="YDR117C"
                     /product="Tma64p"
                     /transcript_id="NM_001180425.3"
                     /db_xref="GI:398365692"
                     /db_xref="GeneID:851695"
     CDS             complement(683946..685643)
                     /gene="TMA64"
                     /locus_tag="YDR117C"
                     /note="hypothetical protein that associates with
                     ribosomes; has a putative RNA binding domain; in mammals
                     the corresponding protein, eIF2D, has been shown to
                     possess translation initiation factor activity"
                     /codon_start=1
                     /product="Tma64p"
                     /protein_id="NP_010402.3"
                     /db_xref="GI:398365693"
                     /db_xref="SGD:S000002524"
                     /db_xref="GeneID:851695"
                     /translation="MFKKEPHIKALSNLKNSERKKLLQTFQKQTNNEEYSFRTSTIKQ
                     TNFNGQKSVGTVYTDENNTPILFKEKHKEQLFPTVYSCWEYPALLPIVLTHGFVIEEH
                     LFNGANLMISGSIPPFDPRCKIGTLCGIASKQAPETVLAIGIVELDLPSFDKVIGETG
                     VAVKIIHHFNDGLSKVFKMKLEPPFVLSTQSKDNNISSKQIESSEQIKAVEKEQEDVK
                     EASVDVEEIAEVLDHFTVSDVDYFITRALYYTLTQDKGLELPISASNFISNHIMRNLP
                     PIDHNEVNVKKTSWKKSAKFLKHFEKEGFLKLKGKGDDLTIVGKNTDKDELKNFVPYK
                     LGCSKSATESRESTTSKEKTSGMMYSLTLYKPFNLAKDLLKEVNLASHTYYTSQDIRS
                     AVSQYISVKNLADTKDKGKVIMDDLLFDMVNKKKKVLNASRIIARGEILHPLLTNNFT
                     EFYQIFKSDDTLLFKAPMKGSLPHIKIITEMKIGRKVITRVSNFEVFQVDPESLAADL
                     RKICSGSTTISESQTFKCAEVQVQGPHGQSIIDHLNKLGIPSKWIDFENKLKKKKRK"
     gene            <685882..>687840
                     /gene="APC4"
                     /locus_tag="YDR118W"
                     /db_xref="GeneID:851696"
     mRNA            <685882..>687840
                     /gene="APC4"
                     /locus_tag="YDR118W"
                     /product="anaphase promoting complex subunit 4"
                     /transcript_id="NM_001180426.3"
                     /db_xref="GI:398365698"
                     /db_xref="GeneID:851696"
     CDS             685882..687840
                     /gene="APC4"
                     /locus_tag="YDR118W"
                     /note="Subunit of the Anaphase-Promoting Complex/Cyclosome
                     (APC/C); APC/C is a ubiquitin-protein ligase required for
                     degradation of anaphase inhibitors, including mitotic
                     cyclins, during the metaphase/anaphase transition;
                     component of the platform domain of the APC/C, based on
                     structural analysis; relative distribution to the nucleus
                     increases upon DNA replication stress"
                     /codon_start=1
                     /product="anaphase promoting complex subunit 4"
                     /protein_id="NP_010403.3"
                     /db_xref="GI:398365699"
                     /db_xref="SGD:S000002525"
                     /db_xref="GeneID:851696"
                     /translation="MSSPINDYFIDYNPLFPIFATRIAKGLAIYRVSDHARLAVIPIR
                     NINLVANYDWDTTTGKFLSIFFKDGTIRIHDIFKDGRLVSFLRIPSTKISKGIWDRIP
                     LRYEPNNRDFACNIIDDLPKLIRFVKDSKRINIVPYTQPNSLWRGPDEDDLDSNEKLD
                     VHVVFNEGNDKITVFFNGDYAVFLSVDNIENENSLKSIIKVQDGFYQCFYEDGTVQTL
                     NLGPLLQSKSSVNLLNYIMVIKELIGYMLTHLEFINRELATPYLDFVKRLCDEAYGYG
                     KLKSELEALFLLGEISCDLEDWLCNSVGEKNFKRWKYLGCEAYQKTVQILTLIFVPAC
                     ERIIIYVEKLRAILQAFSIQNKLSYTSDLTAVEVLLKSSQKLLTMTLNSIIGLGRDET
                     LFEKFFIWFNDRLHEALDEDYKLKFQFEDDLYFGYDLLSYFDRILSKKGTEPSSIIDV
                     KLYRDLINSMSDMEKDIAQSNVNSHIQQHILVDLKTDVFAQKYPSSQINLLDAIKLPK
                     HNYIVYLIQVTKHNSAQEPFSEENKKKLYIGTLKDENLGIISKESSVKIPALFKSYRL
                     SSTRFVPNRVHSLLRDIGLSDSNYHSSHVTDYRGENYENEEDDGTIAIPAYIRENREN
                     DDFIACTAKVSVDGRSASLVFPKEKQNV"
     gene            <688227..>690533
                     /gene="VBA4"
                     /locus_tag="YDR119W"
                     /db_xref="GeneID:851697"
     mRNA            <688227..>690533
                     /gene="VBA4"
                     /locus_tag="YDR119W"
                     /product="Vba4p"
                     /transcript_id="NM_001180427.1"
                     /db_xref="GI:296143472"
                     /db_xref="GeneID:851697"
     CDS             688227..690533
                     /gene="VBA4"
                     /locus_tag="YDR119W"
                     /note="hypothetical protein; proposed role as a basic
                     amino acid permease based on phylogeny; GFP-fusion protein
                     localizes to vacuolar membrane; physical interaction with
                     Atg27p suggests a possible role in autophagy;
                     non-essential gene"
                     /codon_start=1
                     /product="Vba4p"
                     /protein_id="NP_010404.1"
                     /db_xref="GI:6320324"
                     /db_xref="SGD:S000002526"
                     /db_xref="GeneID:851697"
                     /translation="MGKKDRQRKKLREFAKLKNRQRNLRKSVQTLKNEVQREAKVPRT
                     SNQIALGNDKIEEINENSPLLSAPSKQEEVSIPKAVDIDTIDAQPLHEGPKIDDSPQD
                     EVNSIKGKPADKANEDDLKPPSQHEACGNSALQSSITDFSDRSVSPLQSITSCNTPMS
                     EHELPVSSSNSFERADDMPVVQADNQTSSSKSLHIVAPSPEVPVSGDEITSYGYGSIP
                     QSIGDVENGLNPPYVENTSSDELVHDLTRRRIFSSCMCTYLFFIAMDSSIILVIASKI
                     ASEFHELWRLSLVISAYLLSNAIGQLVFLKLSLISSVKLLLCIAQFSFILGGYLSWSS
                     AHFWTFIFARCVTGFGGGSLIALKSTIMNRFSQKNDSRYSLSASMITFAMGVVIGPFM
                     MNLFDSSHGSGWRNAFLIPVPFCLVNASIMLADMYSVKSTLYGRPTPTLWKRFKNTLL
                     SPDLYEILTLTLFLLCFVQVTSLDLTGLKNNTMIQALLFSVIIVCGILFFLIETSDTY
                     MNSVISMSLQGDKRLIWTMIGISFCFAALMCIIPFGTTYFIIVLNLSTLQLAERLSPF
                     FFSIVLGYFSVSYFWKSKGQNFLLKFVLSGATLLLYVALMGVSLNLPVWKQYICLSLP
                     FLGSSMILTLLSNLYHEYHEQRKSPISGSIVYCFGAVGGTVGISLGGYVFHKTLIKLM
                     HEKVMPFSKQGYLKKDLLKIIKHATESSDWVHESAPKFVFQTLIECYLQACRNVFKLS
                     TLFFTITVVAIFIFNRIHCRSQNCLSLS"
     gene            <691014..>691214
                     /gene="COX26"
                     /locus_tag="YDR119W-A"
                     /db_xref="GeneID:3799970"
     mRNA            <691014..>691214
                     /gene="COX26"
                     /locus_tag="YDR119W-A"
                     /product="Cox26p"
                     /transcript_id="NM_001184681.1"
                     /db_xref="GI:296143473"
                     /db_xref="GeneID:3799970"
     CDS             691014..691214
                     /gene="COX26"
                     /locus_tag="YDR119W-A"
                     /note="hypothetical protein; copurifies with respiratory
                     chain supercomplexes composed of Complex III
                     (ubiquinol-cytochrome c reductase) and Complex IV
                     (cytochrome c oxidase)"
                     /codon_start=1
                     /product="Cox26p"
                     /protein_id="NP_001032575.1"
                     /db_xref="GI:82795245"
                     /db_xref="SGD:S000113555"
                     /db_xref="GeneID:3799970"
                     /translation="MFFSQVLRSSARAAPIKRYTGGRIGESWVITEGRRLIPEIFQWS
                     AVLSVCLGWPGAVYFFSKARKA"
     gene            complement(<691549..>693261)
                     /gene="TRM1"
                     /locus_tag="YDR120C"
                     /db_xref="GeneID:851698"
     mRNA            complement(<691549..>693261)
                     /gene="TRM1"
                     /locus_tag="YDR120C"
                     /product="Trm1p"
                     /transcript_id="NM_001180428.3"
                     /db_xref="GI:398365716"
                     /db_xref="GeneID:851698"
     CDS             complement(691549..693261)
                     /gene="TRM1"
                     /locus_tag="YDR120C"
                     /EC_number="2.1.1.216"
                     /note="tRNA methyltransferase; two forms of the protein
                     are made by alternative translation starts; localizes to
                     both the nucleus and mitochondrion to produce the modified
                     base N2,N2-dimethylguanosine in tRNAs in both
                     compartments"
                     /codon_start=1
                     /product="Trm1p"
                     /protein_id="NP_010405.3"
                     /db_xref="GI:398365717"
                     /db_xref="SGD:S000002527"
                     /db_xref="GeneID:851698"
                     /translation="MEGFFRIPLKRANLHGMLKAAISKIKANFTAYGAPRINIEDFNI
                     VKEGKAEILFPKKETVFYNPIQQFNRDLSVTCIKAWDNLYGEECGQKRNNKKSKKKRC
                     AETNDDSSKRQKMGNGSPKEAVGNSNRNEPYINILEALSATGLRAIRYAHEIPHVREV
                     IANDLLPEAVESIKRNVEYNSVENIVKPNLDDANVLMYRNKATNNKFHVIDLDPYGTV
                     TPFVDAAIQSIEEGGLMLVTCTDLSVLAGNGYPEKCFALYGGANMVSHESTHESALRL
                     VLNLLKQTAAKYKKTVEPLLSLSIDFYVRVFVKVKTSPIEVKNVMSSTMTTYHCSRCG
                     SYHNQPLGRISQREGRNNKTFTKYSVAQGPPVDTKCKFCEGTYHLAGPMYAGPLHNKE
                     FIEEVLRINKEEHRDQDDTYGTRKRIEGMLSLAKNELSDSPFYFSPNHIASVIKLQVP
                     PLKKVVAGLGSLGFECSLTHAQPSSLKTNAPWDAIWYVMQKCDDEKKDLSKMNPNTTG
                     YKILSAMPGWLSGTVKSEYDSKLSFAPNEQSGNIEKLRKLKIVRYQENPTKNWGPKAR
                     PNTS"
     gene            <693585..>694175
                     /gene="DPB4"
                     /locus_tag="YDR121W"
                     /db_xref="GeneID:851699"
     mRNA            <693585..>694175
                     /gene="DPB4"
                     /locus_tag="YDR121W"
                     /product="Dpb4p"
                     /transcript_id="NM_001180429.3"
                     /db_xref="GI:398365722"
                     /db_xref="GeneID:851699"
     CDS             693585..694175
                     /gene="DPB4"
                     /locus_tag="YDR121W"
                     /EC_number="2.7.7.7"
                     /note="Subunit of DNA pol epsilon and of ISW2 chromatin
                     accessibility complex; involved in both chromosomal DNA
                     replication and inheritance of telomeric silencing;
                     stabilizes the interaction of Pol epsilon with
                     primer-template DNA, positively affecting the processivity
                     of the polymerase and exonuclease activities of Pol
                     epsilon; interacts with extranucleosomal DNA and acts as
                     anchor point for ISW2 complex that retains its position on
                     DNA during nucleosome mobilization"
                     /codon_start=1
                     /product="Dpb4p"
                     /protein_id="NP_010406.3"
                     /db_xref="GI:398365723"
                     /db_xref="SGD:S000002528"
                     /db_xref="GeneID:851699"
                     /translation="MPPKGWRKDAQGNYPTTSYIKEQENITIQDLLFPKSTIVNLARE
                     VPQQSGKKLLINKDASLALQRGATVFVNHLLLFAREIAKSQDKKSCSVDDVLSALDHI
                     GHSALKGPVRDKLDEYQAAVEQRKKEKLDSGEVDADGDIDMGEDKENVPVEKVKEHDE
                     IEEQGDALQDVEESSEKKQKTESQDVETRVQNLEQT"
     gene            <694700..>697894
                     /gene="KIN1"
                     /locus_tag="YDR122W"
                     /db_xref="GeneID:851700"
     mRNA            <694700..>697894
                     /gene="KIN1"
                     /locus_tag="YDR122W"
                     /product="Kin1p"
                     /transcript_id="NM_001180430.1"
                     /db_xref="GI:296143476"
                     /db_xref="GeneID:851700"
     CDS             694700..697894
                     /gene="KIN1"
                     /locus_tag="YDR122W"
                     /EC_number="2.7.11.1"
                     /note="Serine/threonine protein kinase involved in
                     regulation of exocytosis; localizes to the cytoplasmic
                     face of the plasma membrane; KIN1 has a paralog, KIN2,
                     that arose from the whole genome duplication"
                     /codon_start=1
                     /product="Kin1p"
                     /protein_id="NP_010407.1"
                     /db_xref="GI:6320327"
                     /db_xref="SGD:S000002529"
                     /db_xref="GeneID:851700"
                     /translation="MDDYHVNTAFSMGRGNQQDDGNSESNSMHTQPSTMAPATLRMMG
                     KSPQQQQQQNTPLMPPADIKYANNGNSHQAEQKERQVELEGKSRENAPKPNTTSQSRV
                     SSSQGMPKQFHRKSLGDWEFVETVGAGSMGKVKLAKHRYTNEVCAVKIVNRATKAFLH
                     KEQMLPPPKNEQDVLERQKKLEKEISRDKRTIREASLGQILYHPHICRLFEMCTLSNH
                     FYMLFEYVSGGQLLDYIIQHGSIREHQARKFARGIASALIYLHANNIVHRDLKIENIM
                     ISDSSEIKIIDFGLSNIYDSRKQLHTFCGSLYFAAPELLKANPYTGPEVDVWSFGVVL
                     FVLVCGKVPFDDENSSVLHEKIKQGKVEYPQHLSIEVISLLSKMLVVDPKRRATLKQV
                     VEHHWMVRGFNGPPPSYLPKRVPLTIEMLDINVLKEMYRLEFIDDVEETRSVLVSIIT
                     DPTYVLLSRQYWTLAAKMNAESSDNGNAPNITESFEDPTRAYHPMISIYYLTSEMLDR
                     KHAKIRNQQQRQSHENIEKLSEIPESVKQRDVEVNTTAMKSEPEATLATKDTSVPFTP
                     KNSDGTEPPLHVLIPPRLAMPEQAHTSPTSRKSSDNQRREMEYALSPTPQGNDYQQFR
                     VPSTTGDPSEKAKFGNIFRKLSQRRKKTIEQTSVNSNNSINKPVQKTHSRAVSDFVPG
                     FAKPSYDSNYTMNEPVKTNDSRGGNKGDFPALPADAENMVEKQREKQIEEDIMKLHDI
                     NKQNNEVAKGSGREAYAAQKFEGSDDDENHPLPPLNVAKGRKLHPSARAKSVGHARRE
                     SLKYMRPPMPSSAYPQQELIDTGFLESSDDNKSDSLGNVTSQTNDSVSVHSVNAHINS
                     PSVEKELTDEEILQEASRAPAGSMPSIDFPRSLFLKGFFSVQTTSSKPLPIVRYKIMF
                     VLRKMNIEFKEVKGGFVCMQRFSSNNVAAKREGTPRSIMPLSHHESIRRQGSNKYSPS
                     SPLTTNSIHQRKTSITETYGDDKHSGTSLENIHQQGDGSEGMTTTEKEPIKFEIHIVK
                     VRIVGLAGVHFKKISGNTWLYKELASSILKELKL"
     gene            complement(<698554..>699468)
                     /gene="INO2"
                     /locus_tag="YDR123C"
                     /gene_synonym="DIE1; SCS1"
                     /db_xref="GeneID:851701"
     mRNA            complement(<698554..>699468)
                     /gene="INO2"
                     /locus_tag="YDR123C"
                     /gene_synonym="DIE1; SCS1"
                     /product="Ino2p"
                     /transcript_id="NM_001180431.1"
                     /db_xref="GI:296143477"
                     /db_xref="GeneID:851701"
     CDS             complement(698554..699468)
                     /gene="INO2"
                     /locus_tag="YDR123C"
                     /gene_synonym="DIE1; SCS1"
                     /note="Transcription factor; component of the heteromeric
                     Ino2p/Ino4p basic helix-loop-helix transcription activator
                     that binds inositol/choline-responsive elements (ICREs),
                     required for derepression of phospholipid biosynthetic
                     genes in response to inositol depletion; involved in
                     diauxic shift"
                     /codon_start=1
                     /product="Ino2p"
                     /protein_id="NP_010408.1"
                     /db_xref="GI:6320328"
                     /db_xref="SGD:S000002530"
                     /db_xref="GeneID:851701"
                     /translation="MQQATGNELLGILDLDNDIDFETAYQMLSSNFDDQMSAHIHENT
                     FSATSPPLLTHELGIIPNVATVQPSHVETIPADNQTHHAPLHTHAHYLNHNPHQPSMG
                     FDQALGLKLSPSSSGLLSTNESNAIEQFLDNLISQDMMSSNASMNSESHLHIRSPKKQ
                     HRYTELNQRYPETHPHSNTGELPTNTADVPTEFTTREGPHQPIGNDHYNPPPFSVPEI
                     RIPDSDIPANIEDDPVKVRKWKHVQMEKIRRINTKEAFERLIKSVRTPPKENGKRIPK
                     HILLTCVMNDIKSIRSANEALQHILDDS"
     gene            <700315..>701289
                     /locus_tag="YDR124W"
                     /db_xref="GeneID:851702"
     mRNA            <700315..>701289
                     /locus_tag="YDR124W"
                     /product="hypothetical protein"
                     /transcript_id="NM_001180432.3"
                     /db_xref="GI:398365734"
                     /db_xref="GeneID:851702"
     CDS             700315..701289
                     /locus_tag="YDR124W"
                     /note="hypothetical protein; non-essential gene;
                     expression is strongly induced by alpha factor"
                     /codon_start=1
                     /product="hypothetical protein"
                     /protein_id="NP_010409.3"
                     /db_xref="GI:398365735"
                     /db_xref="SGD:S000002531"
                     /db_xref="GeneID:851702"
                     /translation="MRIGMEELRRALALLNGQGYEFMVFIKEKDHLISESIPKNLFSE
                     SFISSSIEKNPPLTFDPLVNRKRITVYEENIQPAIMLPLDQPLLIQNYLYTAFKLLRQ
                     VPCKAIAKLWIKIIEPRKKTRFPYIKGNAGRPEWWPKDVEHKEPDHLQKADRLKLMCT
                     IIMNVLPQSPFSLEILDELTGVTAAMTIFKKETVKKVIMKNVFEIAKCLCNKDFKQKT
                     ISLDDLNDLAQKQKKSYHSRRFDVNKMVKVEKDLLQQSSGSDSSPSMILPSKESDTEY
                     FPREYPKDPVSEDYSNSISRLENLVEFDPLFLTKLDELTSSDDCKDFI"
     gene            complement(<701397..>702758)
                     /gene="ECM18"
                     /locus_tag="YDR125C"
                     /db_xref="GeneID:851703"
     mRNA            complement(<701397..>702758)
                     /gene="ECM18"
                     /locus_tag="YDR125C"
                     /product="alpha/beta hydrolase family protein"
                     /transcript_id="NM_001180433.3"
                     /db_xref="GI:398365742"
                     /db_xref="GeneID:851703"
     CDS             complement(701397..702758)
                     /gene="ECM18"
                     /locus_tag="YDR125C"
                     /EC_number="2.3.1.-"
                     /note="hypothetical protein; ECM18 has a paralog, ICT1,
                     that arose from the whole genome duplication"
                     /codon_start=1
                     /product="alpha/beta hydrolase family protein"
                     /protein_id="NP_010410.3"
                     /db_xref="GI:398365743"
                     /db_xref="SGD:S000002532"
                     /db_xref="GeneID:851703"
                     /translation="MLLIKRYLMDPESLRRQIMNVYKCYMWKRAFHSNRSLLEVKRRE
                     KSLQRKILERILRPKEENAVKKSGFKLWSSHLNNPHKTYMRLEELQRRIMEEVHVEGI
                     KKNDKLFNEINQWHFQNENTSTVRTPTLLIHGYAASSMSFFRNYPGLSKHIRNLYSID
                     MPASGLSSVPSLEINTTTPLPLDIKFIGENKFKVPYTINANHNKFVIQMYEDFYLDRI
                     EQWRIDNKLGKMNVVGHSFGGYLSFKYAVKYPNSVNKLCLVSPLGVERNIWSVNNNFH
                     SNTLYTIDFKNPNSKFYSKRNMIPKYLFEQQFHILRMMGPLGAKLCWNYIMAAYSRVP
                     SLAYKEYIFELFYGKGGIPEVTTDIFKALFSRCILAKDPLMDSLQYLNVKKLLIVYGQ
                     YDWMNKKAGMFMVKELNNLKNCLEGASYLEIPSSGHNLFLDNPESFNQSIVSFLSDET
                     KSP"
     rep_origin      702887..703132
                     /note="ARS422;
                     Autonomously Replicating Sequence"
                     /db_xref="SGD:S000114834"
     gene            <703234..>704244
                     /gene="SWF1"
                     /locus_tag="YDR126W"
                     /gene_synonym="PSL10"
                     /db_xref="GeneID:851704"
     mRNA            <703234..>704244
                     /gene="SWF1"
                     /locus_tag="YDR126W"
                     /gene_synonym="PSL10"
                     /product="Swf1p"
                     /transcript_id="NM_001180434.1"
                     /db_xref="GI:296143480"
                     /db_xref="GeneID:851704"
     CDS             703234..704244
                     /gene="SWF1"
                     /locus_tag="YDR126W"
                     /gene_synonym="PSL10"
                     /EC_number="2.3.1.225"
                     /note="Palmitoyltransferase that acts on transmembrane
                     proteins; including the SNAREs Snc1p, Syn8p, Tlg1p and
                     likely all SNAREs; contains an Asp-His-His-Cys-cysteine
                     rich (DHHC-CRD) domain; may have a role in vacuole fusion"
                     /codon_start=1
                     /product="Swf1p"
                     /protein_id="NP_010411.1"
                     /db_xref="GI:6320331"
                     /db_xref="SGD:S000002533"
                     /db_xref="GeneID:851704"
                     /translation="MSWNLLFVLLIGFVVLILLSPVFKSTWPFSTFYRNVFQPFLVDD
                     QKYRWKLHLVPLFYTSIYLYLVYTYHMRVESTIKNELFLLERILIVPIIILPPVALGI
                     LAMVSRAEDSKDHKSGSTEEYPYDYLLYYPAIKCSTCRIVKPARSKHCSICNRCVLVA
                     DHHCIWINNCIGKGNYLQFYLFLISNIFSMCYAFLRLWYISLNSTSTLPRAVLTLTIL
                     CGCFTIICAIFTYLQLAIVKEGMTTNEQDKWYTIQEYMREGKLVRSLDDDCPSWFFKC
                     TEQKDDAAEPLQDQHVTFYSTNAYDHKHYNLTHYITIKDASEIPNIYDKGTFLANLTD
                     LI"
     gene            <704484..>709250
                     /gene="ARO1"
                     /locus_tag="YDR127W"
                     /db_xref="GeneID:851705"
     mRNA            <704484..>709250
                     /gene="ARO1"
                     /locus_tag="YDR127W"
                     /product="pentafunctional protein ARO1p"
                     /transcript_id="NM_001180435.1"
                     /db_xref="GI:296143481"
                     /db_xref="GeneID:851705"
     CDS             704484..709250
                     /gene="ARO1"
                     /locus_tag="YDR127W"
                     /EC_number="4.2.3.4"
                     /EC_number="4.2.1.10"
                     /EC_number="2.7.1.71"
                     /EC_number="2.5.1.19"
                     /EC_number="1.1.1.25"
                     /note="Pentafunctional arom protein; catalyzes steps 2
                     through 6 in the biosynthesis of chorismate, which is a
                     precursor to aromatic amino acids"
                     /codon_start=1
                     /product="pentafunctional protein ARO1p"
                     /protein_id="NP_010412.1"
                     /db_xref="GI:6320332"
                     /db_xref="SGD:S000002534"
                     /db_xref="GeneID:851705"
                     /translation="MVQLAKVPILGNDIIHVGYNIHDHLVETIIKHCPSSTYVICNDT
                     NLSKVPYYQQLVLEFKASLPEGSRLLTYVVKPGETSKSRETKAQLEDYLLVEGCTRDT
                     VMVAIGGGVIGDMIGFVASTFMRGVRVVQVPTSLLAMVDSSIGGKTAIDTPLGKNFIG
                     AFWQPKFVLVDIKWLETLAKREFINGMAEVIKTACIWNADEFTRLESNASLFLNVVNG
                     AKNVKVTNQLTNEIDEISNTDIEAMLDHTYKLVLESIKVKAEVVSSDERESSLRNLLN
                     FGHSIGHAYEAILTPQALHGECVSIGMVKEAELSRYFGILSPTQVARLSKILVAYGLP
                     VSPDEKWFKELTLHKKTPLDILLKKMSIDKKNEGSKKKVVILESIGKCYGDSAQFVSD
                     EDLRFILTDETLVYPFKDIPADQQKVVIPPGSKSISNRALILAALGEGQCKIKNLLHS
                     DDTKHMLTAVHELKGATISWEDNGETVVVEGHGGSTLSACADPLYLGNAGTASRFLTS
                     LAALVNSTSSQKYIVLTGNARMQQRPIAPLVDSLRANGTKIEYLNNEGSLPIKVYTDS
                     VFKGGRIELAATVSSQYVSSILMCAPYAEEPVTLALVGGKPISKLYVDMTIKMMEKFG
                     INVETSTTEPYTYYIPKGHYINPSEYVIESDASSATYPLAFAAMTGTTVTVPNIGFES
                     LQGDARFARDVLKPMGCKITQTATSTTVSGPPVGTLKPLKHVDMEPMTDAFLTACVVA
                     AISHDSDPNSANTTTIEGIANQRVKECNRILAMATELAKFGVKTTELPDGIQVHGLNS
                     IKDLKVPSDSSGPVGVCTYDDHRVAMSFSLLAGMVNSQNERDEVANPVRILERHCTGK
                     TWPGWWDVLHSELGAKLDGAEPLECTSKKNSKKSVVIIGMRAAGKTTISKWCASALGY
                     KLVDLDELFEQQHNNQSVKQFVVENGWEKFREEETRIFKEVIQNYGDDGYVFSTGGGI
                     VESAESRKALKDFASSGGYVLHLHRDIEETIVFLQSDPSRPAYVEEIREVWNRREGWY
                     KECSNFSFFAPHCSAEAEFQALRRSFSKYIATITGVREIEIPSGRSAFVCLTFDDLTE
                     QTENLTPICYGCEAVEVRVDHLANYSADFVSKQLSILRKATDSIPIIFTVRTMKQGGN
                     FPDEEFKTLRELYDIALKNGVEFLDLELTLPTDIQYEVINKRGNTKIIGSHHDFQGLY
                     SWDDAEWENRFNQALTLDVDVVKFVGTAVNFEDNLRLEHFRDTHKNKPLIAVNMTSKG
                     SISRVLNNVLTPVTSDLLPNSAAPGQLTVAQINKMYTSMGGIEPKELFVVGKPIGHSR
                     SPILHNTGYEILGLPHKFDKFETESAQLVKEKLLDGNKNFGGAAVTIPLKLDIMQYMD
                     ELTDAAKVIGAVNTVIPLGNKKFKGDNTDWLGIRNALINNGVPEYVGHTAGLVIGAGG
                     TSRAALYALHSLGCKKIFIINRTTSKLKPLIESLPSEFNIIGIESTKSIEEIKEHVGV
                     AVSCVPADKPLDDELLSKLERFLVKGAHAAFVPTLLEAAYKPSVTPVMTISQDKYQWH
                     VVPGSQMLVHQGVAQFEKWTGFKGPFKAIFDAVTKE"
     gene            <709549..>712995
                     /gene="MTC5"
                     /locus_tag="YDR128W"
                     /gene_synonym="SEA3"
                     /db_xref="GeneID:851706"
     mRNA            <709549..>712995
                     /gene="MTC5"
                     /locus_tag="YDR128W"
                     /gene_synonym="SEA3"
                     /product="Mtc5p"
                     /transcript_id="NM_001180436.3"
                     /db_xref="GI:398365748"
                     /db_xref="GeneID:851706"
     CDS             709549..712995
                     /gene="MTC5"
                     /locus_tag="YDR128W"
                     /gene_synonym="SEA3"
                     /note="Subunit of the SEA (Seh1-associated) complex; SEA
                     is a coatomer-related complex that associates dynamically
                     with the vacuole; has N-terminal WD-40 repeats and a
                     C-terminal RING motif; mtc5 is synthetically sick with
                     cdc13-1; relative distribution to vacuolar membrane
                     punctae decreases upon DNA replication stress"
                     /codon_start=1
                     /product="Mtc5p"
                     /protein_id="NP_010413.3"
                     /db_xref="GI:398365749"
                     /db_xref="SGD:S000002535"
                     /db_xref="GeneID:851706"
                     /translation="MCSSINEGPYNSPTFGKSLSLKVDGGFNAVSINPSGRDIVLASR
                     QGLYIIDLDDPFTPPRWLHHITPWQVADVQWSPHPAKPYWIVSTSNQKAIIWNLAKSS
                     SNAIEFVLHGHSRAITDINFNPQHPDVLATCSVDTYVHAWDMRSPHRPFYSTSSWRSA
                     ASQVKWNYKDPNVLASSHGNDIFVWDLRKGSTPLCSLKGHVSSVNSIDFNRFKYSEIM
                     SSSNDGTVKFWDYSKSTTESKRTVTTNFPIWRGRYLPFGEGYCIMPMVGGNNAVYLIN
                     LCDDDDSEQNKKTKLQPIYAFKGHSDRVIDFLWRSRHTCDGDYDDREFQLVTWSKDCD
                     LKLWPISDSIYGKVNFDRGKRLEEKLPDYDYCSYNKEPENRENVQKNEFRRLRENFVT
                     TSGLKKNKTNHITWLSGIRMNSATSQEDLFNETKIQNLGEEVSAIGHKFPKVVFEKIS
                     VSTRELCLTLNGPWSEENPDDYIFLRISINFPLNYPNKGDPPKFTIEENSNLTMSKRQ
                     EILSNLATIGQKYTDSNLYCLEPCIRFVLGEKVSLEDIEEGQEPLLNFDIADHIDFEE
                     LSSLDSSYSDSQNPENLSSQSDIESYKEALVFPDTSNQGLDFGRNLALDTTPVPNGCG
                     SCWTATGELFCFFANEKKPEKKQNAIIKLSQKEAGVEKHPFKIEPQVLYDKEVDSSVI
                     TAADELKARPKRYVDTLGLGGGTNGDSRTYFDDETSSDDSFDSVADDWDDILRNDIIV
                     RTKIPILRGNFKAFSSVHSESGKTVESTKKNKNLVISKNFSSLLSDRKELALEYLFMD
                     ATPEGFARNNALVAEKFDLDEISHCWQILSDMLIDQSDYDPYTTIWNNHPMGIKWFIK
                     EAIVYFERQQNLQMLAMLCCVILSARRKKIPARYYGQELENMEGTIVFNDNESQNTSF
                     WKGSDAFSTRSRSSTVTPNFYGNHLRGKNIHGGDNSSIRSDDHHARLRTHNTLNGSSK
                     FTEPAQKQGSRAISSSPFHSRMPDIKVELLHDDIIEAYEQEDLLHLEVSDIPKFQTYI
                     YQYSKLLFRWGLPLERVKILKVSTDFRSSYSSQGIPPNNNKKSPYNGVLTHWIENNEF
                     GEEKFLARNCNYCDLRVTRSSFICGNCQHVLHSSCARIWWEIGDECPSGCGCNCPEMF
                     DA"
     gene            complement(<713340..>715379)
                     /gene="SAC6"
                     /locus_tag="YDR129C"
                     /gene_synonym="ABP67"
                     /db_xref="GeneID:851707"
     mRNA            complement(join(<713340..715247,715359..>715379))
                     /gene="SAC6"
                     /locus_tag="YDR129C"
                     /gene_synonym="ABP67"
                     /product="fimbrin"
                     /transcript_id="NM_001180437.3"
                     /db_xref="GI:398365758"
                     /db_xref="GeneID:851707"
     CDS             complement(join(713340..715247,715359..715379))
                     /gene="SAC6"
                     /locus_tag="YDR129C"
                     /gene_synonym="ABP67"
                     /note="Fimbrin, actin-bundling protein; cooperates with
                     Scp1p (calponin/transgelin) in the organization and
                     maintenance of the actin cytoskeleton; relocalizes from
                     plasma membrane to cytoplasm upon DNA replication stress"
                     /codon_start=1
                     /product="fimbrin"
                     /protein_id="NP_010414.3"
                     /db_xref="GI:398365759"
                     /db_xref="SGD:S000002536"
                     /db_xref="GeneID:851707"
                     /translation="MNIVKLQRKFPILTQEDLFSTIEKFRAIDLDDKGWVEKQQALEA
                     VSKDGDATYDEARETLKHVGVDASGRVELDDYVGLVAKLRESKTGAAPQTTFNVAPNS
                     TPIVSTAATGLQHKGKGTQAKIIVAGSQTGTTHTINEEERREFTKHINSVLAGDQDIG
                     DLLPFPTDTFQLFDECRDGLVLSKLINDSVPDTIDTRVLNWPKKGKELNNFQASENAN
                     IVINSAKAIGCVVVNVHSEDIIEGREHLILGLIWQIIRRGLLSKIDIKLHPELYRLLE
                     DDETLEQFLRLPPEQILLRWFNYHLKQANWNRRVTNFSKDVSDGENYTILLNQLDPAL
                     CSKAPLQTTDLMERAEQVLQNAEKLDCRKYLTPSSLVAGNPKLNLAFVAHLFNTHPGL
                     EPIQEEEKPEIEEFDAEGEREARVFTLWLNSLDVDPPVISLFDDLKDGLILLQAYEKV
                     MPGAVDFKHVNKRPASGAEISRFKALENTNYAVDLGRAKGFSLVGIEGSDIVDGNKLL
                     TLGLVWQLMRRNISITMKTLSSSGRDMSDSQILKWAQDQVTKGGKNSTIRSFKDQALS
                     NAHFLLDVLNGIAPGYVDYDLVTPGNTEEERYANARLAISIARKLGALIWLVPEDINE
                     VRARLIITFIASLMTLNK"
     gene            complement(<715747..>716622)
                     /gene="FIN1"
                     /locus_tag="YDR130C"
                     /db_xref="GeneID:851708"
     mRNA            complement(<715747..>716622)
                     /gene="FIN1"
                     /locus_tag="YDR130C"
                     /product="Fin1p"
                     /transcript_id="NM_001180438.1"
                     /db_xref="GI:296143484"
                     /db_xref="GeneID:851708"
     CDS             complement(715747..716622)
                     /gene="FIN1"
                     /locus_tag="YDR130C"
                     /note="Spindle pole body-related intermediate filament
                     protein; forms cell cycle-specific filaments between
                     spindle pole bodies in dividing cells; localizes to poles
                     and microtubules of spindle during anaphase and
                     contributes to spindle stability; involved in Glc7p
                     localization and regulation; relative distribution to the
                     nucleus increases upon DNA replication stress"
                     /codon_start=1
                     /product="Fin1p"
                     /protein_id="NP_010415.1"
                     /db_xref="GI:6320335"
                     /db_xref="SGD:S000002537"
                     /db_xref="GeneID:851708"
                     /translation="MSNKSNRRSLRDIGNTIGRNNIPSDKDNVFVRLSMSPLRTTSQK
                     EFLKPPMRISPNKTDGMKHSIQVTPRRIMSPECLKGYVSKETQSLDRPQFKNSNKNVK
                     IQNSDHITNIIFPTSPTKLTFSNENKIGGDGSLTRIRARFKNGLMSPERIQQQQQQHI
                     LPSDAKSNTDLCSNTELKDAPFENDLPRAKLKGKNLLVELKKEEEDVGNGIESLTKSN
                     TKLNSMLANEGKIHKASFQKSVKFKLPDNIVTEETVELKEIKDLLLQMLRRQREIESR
                     LSNIELQLTEIPKHK"
     gene            complement(<716790..>718460)
                     /locus_tag="YDR131C"
                     /db_xref="GeneID:851709"
     mRNA            complement(<716790..>718460)
                     /locus_tag="YDR131C"
                     /product="hypothetical protein"
                     /transcript_id="NM_001180439.1"
                     /db_xref="GI:296143485"
                     /db_xref="GeneID:851709"
     CDS             complement(716790..718460)
                     /locus_tag="YDR131C"
                     /note="F-box protein subunit of SCF ubiquitin ligase
                     complex; substrate-specific adaptor subunit that recruits
                     substrates to a core ubiquitination complex"
                     /codon_start=1
                     /product="hypothetical protein"
                     /protein_id="NP_010416.1"
                     /db_xref="GI:6320336"
                     /db_xref="SGD:S000002538"
                     /db_xref="GeneID:851709"
                     /translation="MFDKLPYEIFKQIAWRIPQEDKISLTYVCKRSYESIIPFIYQNL
                     FLNETYHINGDYDNSFGTCYWSVLNFHYIDEDDSNTKNDMSNRRLAKVKFSYFERTLA
                     ESPKRLCPLINRIRCTWHLNEDVMTNVLKLLSEYGSNLKFVDQFVRSSVNKGLEPLSK
                     QLKTLTLTPPTLMPTHNSVSGSYLNKIDRLLLKCDLSRLEKLSIHINALKYFKNTGSP
                     MKIKALVLNLRPDTLNLAEYDASDDFLKELEYIDIFDASTLRQLEILSWYSRDDFPSG
                     EEGGFDRLYVKWGLEGFWKFPNIEKLSLASLVYSEFFLMNCLAVFHNLKILKLDYMGK
                     FDFDVSLINFLSKQVCGKKLQRFDIHCQLNHRLFFPMTDNPLTRLNFDGFCPCSTCKN
                     TIHEVILKKIFPETRSKLLKNPNKFQAHNFFYQMFFENKIMPYTNIIDNESPAMGWDS
                     VPIETFVRKFNENLQSTIENTENITVNKITREDAISLYHLYLHYLKDVFKVFEQSLPN
                     LEYLTINGIPTKIIQVDELQRCAVPLFYNNGYKSNSVYELVDAEALFS"
     gene            complement(<718816..>720303)
                     /locus_tag="YDR132C"
                     /db_xref="GeneID:851710"
     mRNA            complement(<718816..>720303)
                     /locus_tag="YDR132C"
                     /product="hypothetical protein"
                     /transcript_id="NM_001180440.3"
                     /db_xref="GI:398365764"
                     /db_xref="GeneID:851710"
     CDS             complement(718816..720303)
                     /locus_tag="YDR132C"
                     /note="hypothetical protein; protein increases in
                     abundance and relative distribution to the nucleus
                     increases upon DNA replication stress; YDR132C has a
                     paralog, YLR108C, that arose from the whole genome
                     duplication"
                     /codon_start=1
                     /product="hypothetical protein"
                     /protein_id="NP_010417.3"
                     /db_xref="GI:398365765"
                     /db_xref="SGD:S000002539"
                     /db_xref="GeneID:851710"
                     /translation="MSNSPTVATLSQEYFDPNIPQILPHEKMYKIQVGKSLFKISGAS
                     LSSDGPSFFTEYFSKKRSPSNNDDSNNDTMESNKNEVLFIDRSAEVFEWIYQHLQGYI
                     IEIKDEVQYTMLFADAMYYNLPRLRSLLKETDYYFTNIGGQSFKIAKNLFRREGDSPN
                     YFEIYAATVYIDVEELIISKKLLRPPSHSAPYIPRSSEYFKDLLTLLGGASIDLDDNK
                     RNALIKECRYYRLLNLEQRLIKSHISYNPITRKEEICLLLKDLSKKGITFPASSAFST
                     SPYFEDDFCSINECDSLSKTREQPANKKIKLDMTEKYNDSWNMLCYKRPFLDKHPREL
                     IFQINSTDCTIILNKESQSIHVDITGESAYKFEALFGSHLPNTPSGAPKLKNYQYRFP
                     SDSTQTKIETHYLLPACIYLCDLDINGIKISQVQTLLTDKNKFNDRVIDVSDPLDLRF
                     CSGLKLYLRKSLWKLAVKDGNIMLIAIKAIAFNGTKEYYKGYEYL"
     gene            complement(721071..721481)
                     /locus_tag="YDR134C"
                     /note="hypothetical protein; YDR134C has a paralog, CCW12,
                     that arose from the whole genome duplication"
                     /pseudo
                     /db_xref="GeneID:851712"
                     /db_xref="SGD:S000002541"
     gene            complement(<723004..>727551)
                     /gene="YCF1"
                     /locus_tag="YDR135C"
                     /db_xref="GeneID:851713"
     mRNA            complement(<723004..>727551)
                     /gene="YCF1"
                     /locus_tag="YDR135C"
                     /product="ATP-binding cassette glutathione S-conjugate
                     transporter YCF1"
                     /transcript_id="NM_001180442.3"
                     /db_xref="GI:398365778"
                     /db_xref="GeneID:851713"
     CDS             complement(723004..727551)
                     /gene="YCF1"
                     /locus_tag="YDR135C"
                     /note="Vacuolar glutathione S-conjugate transporter;
                     member of ATP-binding cassette family; ATPase activity
                     required to support vacuole fusion; forms stable complexes
                     with vacuole fusion machinery; regulates Vam7p recruitment
                     to vacuoles; has role in detoxifying metals such as
                     cadmium, mercury, and arsenite; also transports
                     unconjugated bilirubin, selenodigluthatione, and oxidized
                     glutathione; similar to human cystic fibrosis protein
                     CFTR"
                     /codon_start=1
                     /product="ATP-binding cassette glutathione S-conjugate
                     transporter YCF1"
                     /protein_id="NP_010419.3"
                     /db_xref="GI:398365779"
                     /db_xref="SGD:S000002542"
                     /db_xref="GeneID:851713"
                     /translation="MAGNLVSWACKLCRSPEGFGPISFYGDFTQCFIDGVILNLSAIF
                     MITFGIRDLVNLCKKKHSGIKYRRNWIIVSRMALVLLEIAFVSLASLNISKEEAENFT
                     IVSQYASTMLSLFVALALHWIEYDRSVVANTVLLFYWLFETFGNFAKLINILIRHTYE
                     GIWYSGQTGFILTLFQVITCASILLLEALPKKPLMPHQHIHQTLTRRKPNPYDSANIF
                     SRITFSWMSGLMKTGYEKYLVEADLYKLPRNFSSEELSQKLEKNWENELKQKSNPSLS
                     WAICRTFGSKMLLAAFFKAIHDVLAFTQPQLLRILIKFVTDYNSERQDDHSSLQGFEN
                     NHPQKLPIVRGFLIAFAMFLVGFTQTSVLHQYFLNVFNTGMYIKSALTALIYQKSLVL
                     SNEASGLSSTGDIVNLMSVDVQKLQDLTQWLNLIWSGPFQIIICLYSLYKLLGNSMWV
                     GVIILVIMMPLNSFLMRIQKKLQKSQMKYKDERTRVISEILNNIKSLKLYAWEKPYRE
                     KLEEVRNNKELKNLTKLGCYMAVTSFQFNIVPFLVSCCTFAVFVYTEDRALTTDLVFP
                     ALTLFNLLSFPLMIIPMVLNSFIEASVSIGRLFTFFTNEELQPDSVQRLPKVKNIGDV
                     AINIGDDATFLWQRKPEYKVALKNINFQAKKGNLTCIVGKVGSGKTALLSCMLGDLFR
                     VKGFATVHGSVAYVSQVPWIMNGTVKENILFGHRYDAEFYEKTIKACALTIDLAILMD
                     GDKTLVGEKGISLSGGQKARLSLARAVYARADTYLLDDPLAAVDEHVARHLIEHVLGP
                     NGLLHTKTKVLATNKVSALSIADSIALLDNGEITQQGTYDEITKDADSPLWKLLNNYG
                     KKNNGKSNEFGDSSESSVRESSIPVEGELEQLQKLNDLDFGNSDAISLRRASDATLGS
                     IDFGDDENIAKREHREQGKVKWNIYLEYAKACNPKSVCVFILFIVISMFLSVMGNVWL
                     KHWSEVNSRYGSNPNAARYLAIYFALGIGSALATLIQTIVLWVFCTIHASKYLHNLMT
                     NSVLRAPMTFFETTPIGRILNRFSNDIYKVDALLGRTFSQFFVNAVKVTFTITVICAT
                     TWQFIFIIIPLSVFYIYYQQYYLRTSRELRRLDSITRSPIYSHFQETLGGLATVRGYS
                     QQKRFSHINQCRIDNNMSAFYPSINANRWLAYRLELIGSIIILGAATLSVFRLKQGTL
                     TAGMVGLSLSYALQITQTLNWIVRMTVEVETNIVSVERIKEYADLKSEAPLIVEGHRP
                     PKEWPSQGDIKFNNYSTRYRPELDLVLKHINIHIKPNEKVGIVGRTGAGKSSLTLALF
                     RMIEASEGNIVIDNIAINEIGLYDLRHKLSIIPQDSQVFEGTVRENIDPINQYTDEAI
                     WRALELSHLKEHVLSMSNDGLDAQLTEGGGNLSVGQRQLLCLARAMLVPSKILVLDEA
                     TAAVDVETDKVVQETIRTAFKDRTILTIAHRLNTIMDSDRIIVLDNGKVAEFDSPGQL
                     LSDNKSLFYSLCMEAGLVNEN"
     gene            <728259..>730250
                     /gene="RGP1"
                     /locus_tag="YDR137W"
                     /db_xref="GeneID:851714"
     mRNA            <728259..>730250
                     /gene="RGP1"
                     /locus_tag="YDR137W"
                     /product="Rgp1p"
                     /transcript_id="NM_001180444.1"
                     /db_xref="GI:296143488"
                     /db_xref="GeneID:851714"
     CDS             728259..730250
                     /gene="RGP1"
                     /locus_tag="YDR137W"
                     /note="Subunit of a Golgi membrane exchange factor
                     (Ric1p-Rgp1p); this complex catalyzes nucleotide exchange
                     on Ypt6p"
                     /codon_start=1
                     /product="Rgp1p"
                     /protein_id="NP_010421.1"
                     /db_xref="GI:6320340"
                     /db_xref="SGD:S000002544"
                     /db_xref="GeneID:851714"
                     /translation="MRAHRIDTFLIRENIKLEIIHESNSYFGGEHISIAFRFKHLGSQ
                     HELFNYKEKLLTVDKAVEEKLEQQAKVQDDGEGTMENQTWSLKSLLGAFKRTGEPEES
                     VDVDNMKMLNESKMLREKIQKQMYFHQPVTLISGYVQISGVFQYDSEVISESKFKQDE
                     VKMVGLDIVPGHTTNSVLALEDGEHFKGKRNLTNYLNSDYTNVTNGLLFSESGSRGRT
                     GTYNERTLMISNDTSIKTLPLLLIPQTLLFSEISLEPGEVRTFYFKSTKLPKDICPSY
                     SSSKVASINYTLEVGADVLSDDNIEKFSNRVPITIAPYISSNAEQYTSRLDKPAIILK
                     TGNIKELKPRLFTRKVSTASAVSFGRRKSSIIDIDSPLEDNEFVKRVKKNFIELVESN
                     QNVSRDIDELIDLQMGVQFGKDEDSSDPEPNDSHFSNEMVTSAESSLRSDAVTKRRKS
                     YSVRDNISNLEQKMWNDCSLVKSDENSNLLPQLINLQNAYQINRNNETMAKVSLSAPF
                     YKTTDDINLVIELDPITTPLLKVTSLTVSLESFEIINPKYKTEGKGIGSKPKGNSVYE
                     KHFICFDECKSVSVKLLPPRSPTNQITGQFKTDVFQHKWMIGLKFVIIAKTESITLDQ
                     FYEDKKGILFHSKENLEGEEFTCYVPIPILCTSEDFMGW"
     gene            <730578..>732836
                     /gene="HPR1"
                     /locus_tag="YDR138W"
                     /gene_synonym="TRF1"
                     /db_xref="GeneID:851716"
     mRNA            <730578..>732836
                     /gene="HPR1"
                     /locus_tag="YDR138W"
                     /gene_synonym="TRF1"
                     /product="Hpr1p"
                     /transcript_id="NM_001180445.1"
                     /db_xref="GI:296143489"
                     /db_xref="GeneID:851716"
     CDS             730578..732836
                     /gene="HPR1"
                     /locus_tag="YDR138W"
                     /gene_synonym="TRF1"
                     /note="Subunit of THO/TREX complexes; this complex couple
                     transcription elongation with mitotic recombination and
                     with mRNA metabolism and export, subunit of an RNA Pol II
                     complex; regulates lifespan; involved in telomere
                     maintenance; similar to Top1p"
                     /codon_start=1
                     /product="Hpr1p"
                     /protein_id="NP_010422.1"
                     /db_xref="GI:6320342"
                     /db_xref="SGD:S000002545"
                     /db_xref="GeneID:851716"
                     /translation="MSNTEELIQNSIGFLQKTFKALPVSFDSIRHEPLPSSMLHASVL
                     NFEWEPLEKNISAIHDRDSLIDIILKRFIIDSMTNAIEDEEENNLEKGLLNSCIGLDF
                     VYNSRFNRSNPASWGNTFFELFSTIIDLLNSPSTFLKFWPYAESRIEWFKMNTSVEPV
                     SLGESNLISYKQPLYEKLRHWNDILAKLENNDILNTVKHYNMKYKLENFLSELLPINE
                     ESNFNRSASISALQESDNEWNRSARERESNRSSDVIFAADYNFVFYHLIICPIEFAFS
                     DLEYKNDVDRSLSPLLDAILEIEENFYSKIKMNNRTRYSLEEALNTEYYANYDVMTPK
                     LPVYMKHSNAMKMDRNEFWANLQNIKESDDYTLRPTIMDISLSNTTCLYKQLTQEDDD
                     YYRKQFILQLCFTTNLIRNLISSDETRNFYKSCYLRENPLSDIDFENLDEVNKKRGLN
                     LCSYICDNRVLKFYKIKDPDFYRVIRKLMSSDEKFTTAKIDGFKEFQNFRISKEKIPP
                     PAFDETFKKFTFIKMGNKLINNVWKIPTGLDKIEQEVKKPEGVYEAAQAKWESKISSE
                     TSGGEAKDEIIRQWQTLRFLRSRYLFDFDKVNEKTGVDGLFEEPRKVEALDDSFKEKL
                     LYKINQEHRKKLQDAREYKIGKERKKRALEEEASFPEREQKIKSQRINSASQTEGDEL
                     KSEQTQPKGEISEENTKIKSSEVSSQDPDSGVAGEFAPQNTTAQLENPKTEDNNAATS
                     NISNGSSTQDMK"
     gene            complement(<733618..>733924)
                     /gene="RUB1"
                     /locus_tag="YDR139C"
                     /db_xref="GeneID:851717"
     mRNA            complement(join(<733618..733702,733776..>733924))
                     /gene="RUB1"
                     /locus_tag="YDR139C"
                     /product="NEDD8 family protein RUB1"
                     /transcript_id="NM_001180446.3"
                     /db_xref="GI:398365788"
                     /db_xref="GeneID:851717"
     CDS             complement(join(733618..733702,733776..733924))
                     /gene="RUB1"
                     /locus_tag="YDR139C"
                     /note="Ubiquitin-like protein with similarity to mammalian
                     NEDD8; conjugation (neddylation) substrates include the
                     cullins Cdc53p, Rtt101p, and Cul3p; activated by Ula1p and
                     Uba3p (E1 enzyme pair); conjugation mediated by Ubc12p (E2
                     enzyme)"
                     /codon_start=1
                     /product="NEDD8 family protein RUB1"
                     /protein_id="NP_010423.4"
                     /db_xref="GI:398365789"
                     /db_xref="SGD:S000002546"
                     /db_xref="GeneID:851717"
                     /translation="MIVKVKTLTGKEISVELKESDLVYHIKELLEEKEGIPPSQQRLI
                     FQGKQIDDKLTVTDAHLVEGMQLHLVLTLRGGN"
     gene            <734138..>734803
                     /gene="MTQ2"
                     /locus_tag="YDR140W"
                     /db_xref="GeneID:851718"
     mRNA            <734138..>734803
                     /gene="MTQ2"
                     /locus_tag="YDR140W"
                     /product="Mtq2p"
                     /transcript_id="NM_001180447.3"
                     /db_xref="GI:398365790"
                     /db_xref="GeneID:851718"
     CDS             734138..734803
                     /gene="MTQ2"
                     /locus_tag="YDR140W"
                     /EC_number="2.1.1.-"
                     /note="S-adenosylmethionine-dependent methyltransferase;
                     subunit of complex with Trm112p that methylates
                     translation release factor Sup45p (eRF1) in the ternary
                     complex eRF1-eRF3-GTP; similar to E.coli PrmC; member of
                     the seven beta-strand family"
                     /codon_start=1
                     /product="Mtq2p"
                     /protein_id="NP_010424.3"
                     /db_xref="GI:398365791"
                     /db_xref="SGD:S000002547"
                     /db_xref="GeneID:851718"
                     /translation="MLPTPYVKCDYDKVYEPAEDSFLILDCLEKEHDFLKQKFGNRLA
                     IVCEIGSGSGIVTTFLMQNKIIPQENSIHLAVDINPWALEATLDTAKLNSCKSSFLEV
                     IQADLNSSIRNNQVDVLIFNPPYVPAECVPDVPGSREEADQWLDLALLGGKDGMAITD
                     KLLRQLEQILSPDGVAYILFCARNKPKEVIKRFVDTYKWNVKLIETRKAGWEVLSVYS
                     FTR"
     gene            complement(<734901..>739997)
                     /gene="DOP1"
                     /locus_tag="YDR141C"
                     /db_xref="GeneID:851719"
     mRNA            complement(<734901..>739997)
                     /gene="DOP1"
                     /locus_tag="YDR141C"
                     /product="Dop1p"
                     /transcript_id="NM_001180448.1"
                     /db_xref="GI:296143492"
                     /db_xref="GeneID:851719"
     CDS             complement(734901..739997)
                     /gene="DOP1"
                     /locus_tag="YDR141C"
                     /note="Golgi-localized, leucine-zipper domain containing
                     protein; involved in endosome to Golgi transport,
                     organization of the ER, establishing cell polarity, and
                     morphogenesis; detected in highly purified mitochondria in
                     high-throughput studies"
                     /codon_start=1
                     /product="Dop1p"
                     /protein_id="NP_010425.1"
                     /db_xref="GI:6320345"
                     /db_xref="SGD:S000002548"
                     /db_xref="GeneID:851719"
                     /translation="MSLPLKPLTIDSNNKQLDSKQKKFRANVERALERFDSVTEWADY
                     IASLGTLLKALQSWSPKFQNVRYYVPSPYQVSRRLTSSLSPALPAGVHQKTLEVYTYI
                     FEHIGLETLATECNIWIPGILPLMTYASMSVRSHLIELYDNYILLLPQTTLRLLIRPL
                     ISSLLPGIDDESNDFLPLTLKLIETLQENLDDDSLFWQTLFLVMTANKGRRLGGLTWL
                     TRKFPSLNAVPHLVNKIKMEAEENPSETETNDSHLDRKKRKEEAFKVLLPAAKDLVTP
                     EPGLLIRCLVGCLEDENDILIKRSVLDLLLQRLRLDSPVLNVLITSEDKKLLIMSCCR
                     TTLSKDMSLNRRIWNWLLGPTAGGMLNNNGGNSMEYTTSVKSANEESNVYFTKYGLSA
                     LLEGLSDLLSEEESVLTAFRISMAVMDRWEIGSLVIPELFIPLLYSSEKFKQNEQIMK
                     TARTFFDNTETNIIWGKLFQELEDIKNLKILDFVLTNFNIGNDEEIIVRHLPLILLTL
                     LALPSNDKDFDNIYKLQKFSLYNKLLNYIPERALLPLSHSKLKHDDEVSCEELLAKIR
                     GFYTNVSNPSSILEKENIAERLPPFTTEDLTFLIADLIQKKLLSSLWDLENINESSKL
                     FIAIFEKIPESEELKGRSHISWSDKKITQSIFEAIPRLCESNNDAKSEEIVGIVEIFG
                     NYLYSRMEFIESMKLLKVVMMAVWKSLKDPRHQILGVKNLKTLNRFIPSKFIESALVY
                     TFVEEEDISERLSVLDLLWTQLDSDSNLIRRPLELILGELFDDQNPFYLTVSKWILSI
                     LNSGSASRLFYILTDNILKVNRLEKERLDERDDLDMLTYEFQMLAYVLKTNNGRTRKV
                     FSTELTSIKSSTIWKNEDVSTYKSLLLVTLMRFLNIKSNTHAKSIRSALILLDILLDG
                     TEQNFKDIVIFLLQMSSKYIAEEGIEPELIAVSLLDIVSKVLRLSHDNGIKLDIFDDN
                     AAHLKYIDFLVTSVSNMKSPLIVTAYVKLLSESIVYFENSIFRMILPLSASLVQCVQR
                     LFLLEKREGGYYQPIALLLGGLEELLEISHGYLVTEEREGYFSGSNLKGDFIQSVVSN
                     VFSSDSSNEESKIQGERDVILQSFRQVISCCLDIWYWAHNISCKSNDDSSLDATNHNS
                     YKFKFRSKKLLETLFLLEPLELLENLISIRSDNTTVTLVHVLDGNKPAITIPHLLYGV
                     IIRYNRTASVKFSNRDGSRSSTTKLTKGEPSMLKRLSGESIIAFLFNYVDSVENSAME
                     EFYGDFLLFFREVATNYNLYSDVSLSILKLVALISGKVSKTQFGEQKRVRREISDVFF
                     KYLPNAFINFTNLYRGHPDSFKDLEFVVWRVQYIVNDQIGGDKFNTTLATIVNQCLTP
                     YIKPKSEKTIPGYVLELAAVVSHLGSKVKSWRLLIAELFQNDKKLSVIGSDQTWEKII
                     YEWSIYPENKSKILNDLLLEIGSKRSSVTPTLITFNLGSDSEVEYKCQNLLKISYLLM
                     VSPNDAYLLHFSSLISCIFHYLVSKDIKLKGSCWILLRVLLLRFSESHFNDYWSMISY
                     CLQTNLQEFYESLQIQSEVDPQTILQVCKTLDLLLLLNMEGFTSTNEWIFVIDTINCV
                     YKTNSFVALVDEIAEFKDYEITKTDDLELPTTLKDGLPLLRGIHKIERHTQLRSFFQN
                     LSYLHYEKVYGLGSVDLYGCGEDLKKDILS"
     gene            complement(<740473..>741600)
                     /gene="PEX7"
                     /locus_tag="YDR142C"
                     /gene_synonym="PAS7; PEB1"
                     /db_xref="GeneID:851720"
     mRNA            complement(<740473..>741600)
                     /gene="PEX7"
                     /locus_tag="YDR142C"
                     /gene_synonym="PAS7; PEB1"
                     /product="Pex7p"
                     /transcript_id="NM_001180449.1"
                     /db_xref="GI:296143493"
                     /db_xref="GeneID:851720"
     CDS             complement(740473..741600)
                     /gene="PEX7"
                     /locus_tag="YDR142C"
                     /gene_synonym="PAS7; PEB1"
                     /note="Peroxisomal signal receptor for peroxisomal matrix
                     proteins; recognizes the N-terminal nonapeptide signal
                     (PTS2); WD repeat protein; defects in human homolog cause
                     lethal rhizomelic chondrodysplasia punctata (RCDP)"
                     /codon_start=1
                     /product="Pex7p"
                     /protein_id="NP_010426.1"
                     /db_xref="GI:6320346"
                     /db_xref="SGD:S000002549"
                     /db_xref="GeneID:851720"
                     /translation="MLRYHMQGFSGYGVQYSPFFDNRLAVAAGSNFGLVGNGKLFILE
                     IDRSGRIVEVNSFLTQDCLFDLAWNESHENQVLVAQGDGTLRLFDTTFKEFPIAIFKE
                     HEREVFSCNWNLVNRQNFLSSSWDGSIKIWSPLRKQSLMTLTPRPLEITKMVDPLNAI
                     ILKKKSFTGISKNRNCVYQAQFSPHDQNLVLSCSGNSYASLFDIRLPSGKNQNNFLVH
                     SGLEALTCDFNKYRPYVVATGGVDNAIRIWDIRMLNKNESATIKRTVPGQLHNSSCIN
                     EIPNAHGLAIRKVTWSPHHSNILMSASYDMTCRIWRDLSNDGAKETYKTNSTDATKGS
                     IFNFTQHSEFVFGADWSLWGKPGYVASTAWDGNLFVWNGLG"
     gene            complement(<742042..>743874)
                     /gene="SAN1"
                     /locus_tag="YDR143C"
                     /db_xref="GeneID:851721"
     mRNA            complement(<742042..>743874)
                     /gene="SAN1"
                     /locus_tag="YDR143C"
                     /product="ubiquitin-protein ligase SAN1"
                     /transcript_id="NM_001180450.3"
                     /db_xref="GI:398365818"
                     /db_xref="GeneID:851721"
     CDS             complement(742042..743874)
                     /gene="SAN1"
                     /locus_tag="YDR143C"
                     /note="Ubiquitin-protein ligase; involved in
                     proteasome-dependent degradation of aberrant nuclear
                     proteins; targets substrates with regions of exposed
                     hydrophobicity containing 5 or more contiguous hydrophobic
                     residues; contains intrinsically disordered regions that
                     contribute to substrate recognition; prefers a window of
                     exposed hydrophobicity that causes a particular level of
                     protein insolubility, suggesting that San1p evolved to
                     target highly aggregation-prone proteins"
                     /codon_start=1
                     /product="ubiquitin-protein ligase SAN1"
                     /protein_id="NP_010427.3"
                     /db_xref="GI:398365819"
                     /db_xref="SGD:S000002550"
                     /db_xref="GeneID:851721"
                     /translation="MSESGQEQNRGTNTSPNNAENNNNSNAASGPLNGGAEQTRNITV
                     SIQYSYFTPERLAHLSNISNNDNNENNSAASGSTIANGTGPSFGIGNGGHQPDGALVL
                     SFRDVPASTPQDRLNSFISVAAQLAMERFNRLLNRPKGISKDEFDKLPVLQVSDLPKA
                     EGPLCSICYDEYEDEVDSTKAKRKRDSENEEESEGTKKRKDNEGAPLRTTADNDSNPS
                     ITNATVVEPPSIPLTEQQRTLNDEETNPSYKHSPIKLPCGHIFGRECIYKWSRLENSC
                     PLCRQKISESVGVQRAAQQDTDEVAANEAAFERIRRVLYDPTAVNSTNENSSAPSENT
                     SNTTVPTIGNASSGEQMLSRTGFFLVPQNGQPLHNPVRLPPNDSDRNGVNGPSSTTQN
                     PPSNSGGSNNNQSPRWVPIPLTLFQFHSPNPNPSASDSSASPSAANGPNSNNTSSDAT
                     DPHHNRLRAVLDHIFNVAQRGTSDTSATTAPGAQTVHNQGRNDSSSSDTTQGSSFLEN
                     ISRLTGHFTNGSRDNNNDNNHSNDQQRGGSTGENNRNNLFSSGVASYRNQNGDVTTVE
                     LRNNNSAAFPPTDENPSQGQGSSSSDTTIHNDVPNDNNEQRSSQ"
     gene            complement(<744311..>746101)
                     /gene="MKC7"
                     /locus_tag="YDR144C"
                     /gene_synonym="YPS2"
                     /db_xref="GeneID:851722"
     mRNA            complement(<744311..>746101)
                     /gene="MKC7"
                     /locus_tag="YDR144C"
                     /gene_synonym="YPS2"
                     /product="Mkc7p"
                     /transcript_id="NM_001180451.3"
                     /db_xref="GI:398365834"
                     /db_xref="GeneID:851722"
     CDS             complement(744311..746101)
                     /gene="MKC7"
                     /locus_tag="YDR144C"
                     /gene_synonym="YPS2"
                     /EC_number="3.4.23.41"
                     /note="GPI-anchored aspartyl protease; member of the
                     yapsin family of proteases involved in cell wall growth
                     and maintenance; shares functions with Yap3p and Kex2p;
                     MKC7 has a paralog, YPS1, that arose from the whole genome
                     duplication"
                     /codon_start=1
                     /product="Mkc7p"
                     /protein_id="NP_010428.3"
                     /db_xref="GI:398365835"
                     /db_xref="SGD:S000002551"
                     /db_xref="GeneID:851722"
                     /translation="MKLSVLTFVVDALLVCSSIVDAGVTDFPSLPSNEVYVKMNFQKK
                     YGSSFENALDDTKGRTRLMTRDDDYELVELTNQNSFYSVELDIGTPPQKVTVLVDTGS
                     SDLWVTGSDNPYCSTKKKDTTGSSFKQVNKDALASVVESVFTEISYDTTIVTSEATAT
                     FDSTASTSQLIDCATYGTFNTSKSSTFNSNNTEFSIAYGDTTFASGTWGHDQLSLNDL
                     NITGLSFAVANETNSTVGVLGIGLPGLESTYSGVSLSSVQKSYTYNNFPMVLKNSGVI
                     KSTAYSLFANDSDSKHGTILFGAVDHGKYAGDLYTIPIINTLQHRGYKDPIQFQVTLQ
                     GLGTSKGDKEDNLTTLTTTKIPVLLDSGTTISYMPTELVKMLADQVGATYSSAYGYYI
                     MDCIKEMEEESSIIFDFGGFYLSNWLSDFQLVTDSRSNICILGIAPQSDPTIILGDNF
                     LANTYVVYDLDNMEISMAQANFSDDGEYIEIIESAVPSALKAPGYSSTWSTYESIVSG
                     GNMFSTAANSSISYFASTSHSATSSSSSKGQKTQTSTTALSISKSTSSTSSTGMLSPT
                     SSSSTRKENGGHNLNPPFFARFITAIFHHI"
     gene            <746738..>748357
                     /gene="TAF12"
                     /locus_tag="YDR145W"
                     /gene_synonym="TAF61; TAF68"
                     /db_xref="GeneID:851723"
     mRNA            <746738..>748357
                     /gene="TAF12"
                     /locus_tag="YDR145W"
                     /gene_synonym="TAF61; TAF68"
                     /product="Taf12p"
                     /transcript_id="NM_001180452.1"
                     /db_xref="GI:296143496"
                     /db_xref="GeneID:851723"
     CDS             746738..748357
                     /gene="TAF12"
                     /locus_tag="YDR145W"
                     /gene_synonym="TAF61; TAF68"
                     /note="Subunit (61/68 kDa) of TFIID and SAGA complexes;
                     involved in RNA polymerase II transcription initiation and
                     in chromatin modification, similar to histone H2A"
                     /codon_start=1
                     /product="Taf12p"
                     /protein_id="NP_010429.1"
                     /db_xref="GI:6320349"
                     /db_xref="SGD:S000002552"
                     /db_xref="GeneID:851723"
                     /translation="MSSNPENSGVNANNNTGTGNADAITGAQQNMVLQPRQLQEMAAK
                     FRTLLTEARNVGETTPRGKELMFQAAKIKQVYDALTLNRRRQQAAQAYNNTSNSNSSN
                     PASIPTENVPNSSQQQQQQQQQTRNNSNKFSNMIKQVLTPEENQEYEKLWQNFQVRHT
                     SIKEKETYLKQNIDRLEQEINKQTDEGPKQQLQEKKIELLNDWKVLKIEYTKLFNNYQ
                     NSKKTFYVECARHNPALHKFLQESTQQQRVQQQRVQQQQQQQQQQQQQQQQQQQQQQQ
                     RQGQNQRKISSSNSTEIPSVTGPDALKSQQQQQNTITATNNPRGNVNTSQTEQSKAKV
                     TNVNATASMLNNISSSKSAIFKQTEPAIPISENISTKTPAPVAYRSNRPTITGGSAMN
                     ASALNTPATTKLPPYEMDTQRVMSKRKLRELVKTVGIDEGDGETVIDGDVEELLLDLA
                     DDFVTNVTAFSCRLAKHRKSDNLEARDIQLHLERNWNIRIPGYSADEIRSTRKWNPSQ
                     NYNQKLQSITSDKVAAAKNNGNNVASLNTKK"
     rep_origin      748392..748637
                     /note="ARS451;
                     Autonomously Replicating Sequence"
                     /db_xref="SGD:S000119070"
     gene            complement(<748613..>750742)
                     /gene="SWI5"
                     /locus_tag="YDR146C"
                     /db_xref="GeneID:851724"
     mRNA            complement(<748613..>750742)
                     /gene="SWI5"
                     /locus_tag="YDR146C"
                     /product="Swi5p"
                     /transcript_id="NM_001180453.1"
                     /db_xref="GI:296143497"
                     /db_xref="GeneID:851724"
     CDS             complement(748613..750742)
                     /gene="SWI5"
                     /locus_tag="YDR146C"
                     /note="Transcription factor that recruits Mediator and
                     Swi/Snf complexes; activates transcription of genes
                     expressed at the M/G1 phase boundary and in G1 phase;
                     required for expression of the HO gene controlling mating
                     type switching; localization to nucleus occurs during G1
                     and appears to be regulated by phosphorylation by Cdc28p
                     kinase; SWI5 has a paralog, ACE2, that arose from the
                     whole genome duplication"
                     /codon_start=1
                     /product="Swi5p"
                     /protein_id="NP_010430.1"
                     /db_xref="GI:6320350"
                     /db_xref="SGD:S000002553"
                     /db_xref="GeneID:851724"
                     /translation="MDTSNSWFDASKVQSLNFDLQTNSYYSNARGSDPSSYAIEGEYK
                     TLATDDLGNILNLNYGETNEVIMNEINDLNLPLGPLSDEKSVKVSTFSELIGNDWQSM
                     NFDLENNSREVTLNATSLLNENRLNQDSGMTVYQKTMSDKPHDEKKISMADNLLSTIN
                     KSEINKGFDRNLGELLLQQQQELREQLRAQQEANKKLELELKQTQYKQQQLQATLENS
                     DGPQFLSPKRKISPASENVEDVYANSLSPMISPPMSNTSFTGSPSRRNNRQKYCLQRK
                     NSSGTVGPLCFQELNEGFNDSLISPKKIRSNPNENLSSKTKFITPFTPKSRVSSATSN
                     SANITPNNLRLDFKINVEDQESEYSEKPLGLGIELLGKPGPSPTKSVSLKSASVDIMP
                     TIPGSVNNTPSVNKVSLSSSYIDQYTPRGKQLHFSSISENALGINAATPHLKPPSQQA
                     RHREGVFNDLDPNVLTKNTDNEGDDNEENEPESRFVISETPSPVLKSQSKYEGRSPQF
                     GTHIKEINTYTTNSPSKITRKLTTLPRGSIDKYVKEMPDKTFECLFPGCTKTFKRRYN
                     IRSHIQTHLEDRPYSCDHPGCDKAFVRNHDLIRHKKSHQEKAYACPCGKKFNREDALV
                     VHRSRMICSGGKKYENVVIKRSPRKRGRPRKDGTSSVSSSPIKENINKDHNGQLMFKL
                     EDQLRRERSYDGNGTGIMVSPMKTNQR"
     gene            <751631..>753235
                     /gene="EKI1"
                     /locus_tag="YDR147W"
                     /db_xref="GeneID:851725"
     mRNA            <751631..>753235
                     /gene="EKI1"
                     /locus_tag="YDR147W"
                     /product="bifunctional choline kinase/ethanolamine kinase
                     EKI1"
                     /transcript_id="NM_001180454.3"
                     /db_xref="GI:398365848"
                     /db_xref="GeneID:851725"
     CDS             751631..753235
                     /gene="EKI1"
                     /locus_tag="YDR147W"
                     /EC_number="2.7.1.82"
                     /note="Ethanolamine kinase; primarily responsible for
                     phosphatidylethanolamine synthesis via the
                     CDP-ethanolamine pathway; exhibits some choline kinase
                     activity, thus contributing to phosphatidylcholine
                     synthesis via the CDP-choline pathway; EKI1 has a paralog,
                     CKI1, that arose from the whole genome duplication"
                     /codon_start=1
                     /product="bifunctional choline kinase/ethanolamine kinase
                     EKI1"
                     /protein_id="NP_010431.3"
                     /db_xref="GI:398365849"
                     /db_xref="SGD:S000002554"
                     /db_xref="GeneID:851725"
                     /translation="MYTNYSLTSSDAMPRTYLVGTASPEMSKKKRQSANCDKPTRRVI
                     HIIDTNEHSEVDLKNELPITCTNEDGEMTSSSWTSQTANDFLKLAYVNAKLDPSLPSQ
                     YFKQDIINVLQSLEIPGWSVPGSKESSLNKNLLTLTQIKGALTNVIYKIHYPNLPPLL
                     MRIFGDSIDSVIDREYELKVIARLSFYDLGPKLEGFFENGRFEKYIEGSRTSTQADFI
                     DRDTSIKIAKKLKELHCTVPLTHKEITDQPSCWTTFDQWIKLIDSHKEWVSNNVNISE
                     NLRCSSWNFFLKSFKNYKRWLYNDSAFTSKLLREDDKDSMINSGLKMVFCHNDLQHGN
                     LLFKSKGKDDISVGDLTIIDFEYAGPNPVVFDLSNHLNEWMQDYNDVQSFKSHIDKYP
                     KEEDILVFAQSYINHMNENHVKIASQEVRILYNLIIEWRPCTQLFWCLWALLQSGRLP
                     QRPLIEGEKLMSEKAGLGDETHLMEHKNKENGKYDCSEDDSFNYLGFCKEKMSVFWGD
                     LITLGVIDKDCPDIGKTDYLDTKLIF"
     rep_origin      753167..753398
                     /note="ARS423;
                     Autonomously Replicating Sequence"
                     /db_xref="SGD:S000118438"
     gene            complement(<753675..>755066)
                     /gene="KGD2"
                     /locus_tag="YDR148C"
                     /db_xref="GeneID:851726"
     mRNA            complement(<753675..>755066)
                     /gene="KGD2"
                     /locus_tag="YDR148C"
                     /product="alpha-ketoglutarate dehydrogenase KGD2"
                     /transcript_id="NM_001180455.3"
                     /db_xref="GI:398365854"
                     /db_xref="GeneID:851726"
     CDS             complement(753675..755066)
                     /gene="KGD2"
                     /locus_tag="YDR148C"
                     /EC_number="2.3.1.61"
                     /note="Dihydrolipoyl transsuccinylase; component of the
                     mitochondrial alpha-ketoglutarate dehydrogenase complex,
                     which catalyzes the oxidative decarboxylation of
                     alpha-ketoglutarate to succinyl-CoA in the TCA cycle;
                     phosphorylated"
                     /codon_start=1
                     /product="alpha-ketoglutarate dehydrogenase KGD2"
                     /protein_id="NP_010432.3"
                     /db_xref="GI:398365855"
                     /db_xref="SGD:S000002555"
                     /db_xref="GeneID:851726"
                     /translation="MLSRATRTAAAKSLVKSKVARNVMAASFVKRHASTSLFKQANKV
                     ESLGSIYLSGKKISVAANPFSITSNRFKSTSIEVPPMAESLTEGSLKEYTKNVGDFIK
                     EDELLATIETDKIDIEVNSPVSGTVTKLNFKPEDTVTVGEELAQVEPGEAPAEGSGES
                     KPEPTEQAEPSQGVAARENSSEETASKKEAAPKKEAAPKKEVTEPKKADQPKKTVSKA
                     QEPPVASNSFTPFPRTETRVKMNRMRLRIAERLKESQNTAASLTTFNEVDMSALMEMR
                     KLYKDEIIKKTGTKFGFMGLFSKACTLAAKDIPAVNGAIEGDQIVYRDYTDISVAVAT
                     PKGLVTPVVRNAESLSVLDIENEIVRLSHKARDGKLTLEDMTGGTFTISNGGVFGSLY
                     GTPIINSPQTAVLGLHGVKERPVTVNGQIVSRPMMYLALTYDHRLLDGREAVTFLKTV
                     KELIEDPRKMLLW"
     gene            <755628..>763874
                     /gene="NUM1"
                     /locus_tag="YDR150W"
                     /gene_synonym="PAC12"
                     /db_xref="GeneID:851727"
     mRNA            <755628..>763874
                     /gene="NUM1"
                     /locus_tag="YDR150W"
                     /gene_synonym="PAC12"
                     /product="Num1p"
                     /transcript_id="NM_001180457.1"
                     /db_xref="GI:296143500"
                     /db_xref="GeneID:851727"
     CDS             755628..763874
                     /gene="NUM1"
                     /locus_tag="YDR150W"
                     /gene_synonym="PAC12"
                     /note="Protein required for nuclear migration; component
                     of the mitochondria-ER-cortex-ancor (MECA); required for
                     the association of mitochondria with the cell cortex and
                     for accurate distribution of mitochondrial network;
                     interacts with Mdm36p to link the ER and motochondria at
                     the cortex; localizes to the mother cell cortex and the
                     bud tip; may mediate interactions of dynein and
                     cytoplasmic microtubules with the cell cortex"
                     /codon_start=1
                     /product="Num1p"
                     /protein_id="NP_010434.1"
                     /db_xref="GI:6320353"
                     /db_xref="SGD:S000002557"
                     /db_xref="GeneID:851727"
                     /translation="MSHNNRHKKNNDKDSSAGQYANSIDNSLSQESVSTNGVTRMANL
                     KADECGSGDEGDKTKRFSISSILSKRETKDVLPEFAGSSSHNGVLTANSSKDMNFTLE
                     LSENLLVECRKLQSSNEAKNEQIKSLKQIKESLSDKIEELTNQKKSFMKELDSTKDLN
                     WDLESKLTNLSMECRQLKELKKKTEKSWNDEKESLKLLKTDLEILTLTKNGMENDLSS
                     QKLHYDKEISELKERILDLNNENDRLLISVSDLTSEINSLQSNRTERIKIQKQLDDAK
                     ASISSLKRKVQKKYYQKQHTSDTTVTSDPDSEGTTSEEDIFDIVIEIDHMIETGPSVE
                     DISEDLVKKYSEKNNMILLSNDSYKNLLQKSESASKPKDDELMTKEVAENLNMIALPN
                     DDNYSKKEFSLESHIKYLEASGYKVLPLEEFENLNESLSNPSYNYLKEKLQALKKIPI
                     DQSTFNLLKEPTIDFLLPLTSKIDCLIIPTKDYNDLFESVKNPSIEQMKKCLEAKNDL
                     QSNICKWLEERNGCKWLSNDLYFSMVNKIETPSKQYLSDKAKEYDQVLIDTKALEGLK
                     NPTIDFLREKASASDYLLLKKEDYVSPSLEYLVEHAKATNHHLLSDSAYEDLVKCKEN
                     PDMEFLKEKSAKLGHTVVSNEAYSELEKKLEQPSLEYLVEHAKATNHHLLSDSAYEDL
                     VKCKENPDMEFLKEKSAKLGHTVVSNEAYSELQRKYSELEKEVEQPSLAYLVEHAKAT
                     DHHLLSDSAYEDLVKCKENPDVEFLKEKSAKLGHTVVSSEEYSELQRKYSELEKEVEQ
                     PSLAYLVEHAKATDHHLLSDSAYEELVKCKENPDMEFLKEKSAKLGHTVVSNEAYSEL
                     EKKLEQPSLAYLVEHAKATDHHLLSDSAYEDLVKCKENSDVEFLKEKSAKLGHTVVSN
                     EAYSELEKKLEQPSLAYLVEHAKATDHHLLSDSAYEDLVKCKENPDMEFLKEKSAKLG
                     HTVVSNEAYSELEKKLEQPSLEYLVEHAKATNHHLLSDSAYEDLVKCKENPDMEFLKE
                     KSAKLGHTVVSNEAYSELEKKLEQPSLEYLVEHAKATNHHLLSDSAYEELVKCKENPD
                     VEFLKEKSAKLGHTVVSNEAYSELEKKLEQPSLEYLVEHAKATNHHLLSDSAYEELVK
                     CKENPDVEFLKEKSAKLGHTVVSNEAYSELEKKLEQPSLAYLVEHAKATDHHLLSDSA
                     YEDLVKCKENPDVEFLKEKSAKLGHTVVSNEAYSELEKKLEQPSLAYLVEHAKATDHH
                     LLSDSAYEDLVKCKENPDMEFLKEKSAKLGHTVVSNEAYSELEKKLEQPSLEYLVEHA
                     KATNHHLLSDSAYEDLVKCKENPDMEFLKEKSAKLGHTVVSNKEYSELEKKLEQPSLE
                     YLVKHAEQIQSKIISISDFNTLANPSMEDMASKLQKLEYQIVSNDEYIALKNTMEKPD
                     VELLRSKLKGYHIIDTTTYNELVSNFNSPTLKFIEEKAKSKGYRLIEPNEYLDLNRIA
                     TTPSKEEIDNFCKQIGCYALDSKEYERLKNSLENPSKKFIEENAALLDLVLVDKTEYQ
                     AMKDNASNKKSLIPSTKALDFVTMPAPQLASAEKSSLQKRTLSDIENELKALGYVAIR
                     KENLPNLEKPIVDNASKNDVLNLCSKFSLVPLSTEEYDNMRKEHTKILNILGDPSIDF
                     LKEKCEKYQMLIISKHDYEEKQEAIENPGYEFILEKASALGYELVSEVELDRMKQMID
                     SPDIDYMQEKAARNEMVLLRNEEKEALQKKIEYPSLTFLIEKAAGMNKILVDQIEYDE
                     TIRKCNHPTRMELEESCHHLNLVLLDQNEYSTLREPLENRNVEDLINTLSKLNYIAIP
                     NTIYQDLIGKYENPNFDYLKDSLNKMDYVAISRQDYELMVAKYEKPQLDYLKISSEKI
                     DHIVVPLSEYNLMVTNYRNPSLSYLKEKAVLNNHILIKEDDYKNILAVSEHPTVIHLS
                     EKASLLNKVLVDKDDFATMSRSIEKPTIDFLSTKALSMGKILVNESTHKRNEKLLSEP
                     DSEFLTMKAKEQGLIIISEKEYSELRDQIDRPSLDVLKEKAAIFDSIIVENIEYQQLV
                     NTTSPCPPITYEDLKVYAHQFGMELCLQKPNKLSGAERAERIDEQSINTTSSNSTTTS
                     SMFTDALDDNIEELNRVELQNNEDYTDIISKSSTVKDATIFIPAYENIKNSAEKLGYK
                     LVPFEKSNINLKNIEAPLFSKDNDDTSVASSIDLDHLSRKAEKYGMTLISDQEFEEYH
                     ILKDNAVNLNGGMEEMNNPLSENQNLAAKTTNTAQEGAFQNTVPHNDMDNEEVEYGPD
                     DPTFTVRQLKKPAGDRNLILTSREKTLLSRDDNIMSQNEAVYGDDISDSFVDESQEIK
                     NDVDIIKTQAMKYGMLCIPESNFVGASYASAQDMSDIVVLSASYYHNLMSPEDMKWNC
                     VSNEELQAEVKKRGLQIALTTKEDKKGQATASKHEYVSHKLNNKTSTVSTKSGAKKGL
                     AEAAATTAYEDSESHPQIEEQSHRTNHHKHHKRQQSLNSNSTSKTTHSSRNTPASRRD
                     IVASFMSRAGSASRTASLQTLASLNEPSIIPALTQTVIGEYLFKYYPRLGPFGFESRH
                     ERFFWVHPYTLTLYWSASNPILENPANTKTKGVAILGVESVTDPNPYPTGLYHKSIVV
                     TTETRTIKFTCPTRQRHNIWYNSLRYLLQRNMQGISLEDIADDPTDNMYSGKIFPLPG
                     ENTKSSSKRLSASRRSVSTRSLRHRVPQSRSFGNLR"
     gene            complement(<764178..>765155)
                     /gene="CTH1"
                     /locus_tag="YDR151C"
                     /db_xref="GeneID:851729"
     mRNA            complement(<764178..>765155)
                     /gene="CTH1"
                     /locus_tag="YDR151C"
                     /product="Cth1p"
                     /transcript_id="NM_001180458.1"
                     /db_xref="GI:296143501"
                     /db_xref="GeneID:851729"
     CDS             complement(764178..765155)
                     /gene="CTH1"
                     /locus_tag="YDR151C"
                     /note="Member of the CCCH zinc finger family; similar to
                     mammalian Tis11 protein, which activates transcription and
                     also has a role in mRNA degradation; may function with
                     Tis11p in iron homeostasis; CTH1 has a paralog, TIS11,
                     that arose from the whole genome duplication"
                     /codon_start=1
                     /product="Cth1p"
                     /protein_id="NP_010435.1"
                     /db_xref="GI:6320355"
                     /db_xref="SGD:S000002558"
                     /db_xref="GeneID:851729"
                     /translation="MMPNVAPNSYYLNIPNANSTSTTTSSIFSDLNKEYESKIKEIEE
                     YYIKTLLNENTDNDDSSSSEGHNINETDILSEYSPRPSPWLPSKPNCYHPLGDFKDLI
                     ISDSRPTNTLPINNPFAGNNNISTLATTEKKRKKRSLEVEINPTYTTSAFSLPLTAEN
                     LQKLSQVDSQSTGLPYTLPIQKTTKLEPCRRAPLQLPQLVNKTLYKTELCESFTIKGY
                     CKYGNKCQFAHGLNELKFKKKSNNYRTKPCINWSKLGYCPYGKRCCFKHGDDKDVEIY
                     QNANDGRSKDTALTPLPTSLAPSNNDNITNLSKPRNLHTSVKALQRMTW"
     gene            <765706..>766503
                     /gene="GIR2"
                     /locus_tag="YDR152W"
                     /db_xref="GeneID:851730"
     mRNA            <765706..>766503
                     /gene="GIR2"
                     /locus_tag="YDR152W"
                     /product="Gir2p"
                     /transcript_id="NM_001180459.3"
                     /db_xref="GI:398365864"
                     /db_xref="GeneID:851730"
     CDS             765706..766503
                     /gene="GIR2"
                     /locus_tag="YDR152W"
                     /note="Highly-acidic RWD domain-containing hypothetical
                     protein; cytoplasmic; forms a complex with Rbg2p;
                     interacts with Rbg1p and Gcn1p; associates with
                     translating ribosomes; putative intrinsically unstructured
                     protein"
                     /codon_start=1
                     /product="Gir2p"
                     /protein_id="NP_010436.3"
                     /db_xref="GI:398365865"
                     /db_xref="SGD:S000002559"
                     /db_xref="GeneID:851730"
                     /translation="MDYKEEQKQELEVLESIYPDELRIINDEYPKIKFEVAIKLELDT
                     GDSTSVLTKEHTIIAEFKLPENYPDEPCLISLEAQEVALNDNEEDNEEDEDEVEYDDH
                     GNKVLKKFENLPDLISFKGYLPELTVQLESQIETDMLLGMQMCFALISSIKERCEQWY
                     SEQLNKLEKQYELEAQEREKKEQAKFHGTKVTRESYLEWRSKFRQELKLDERDQVRRM
                     KAHHGKLTGKQMFEQGVVGTGDEYMEEDDASVDDVAKGLAKTEIANQ"
     gene            complement(<766736..>767971)
                     /gene="ENT5"
                     /locus_tag="YDR153C"
                     /db_xref="GeneID:851731"
     mRNA            complement(<766736..>767971)
                     /gene="ENT5"
                     /locus_tag="YDR153C"
                     /product="Ent5p"
                     /transcript_id="NM_001180460.3"
                     /db_xref="GI:398365866"
                     /db_xref="GeneID:851731"
     CDS             complement(766736..767971)
                     /gene="ENT5"
                     /locus_tag="YDR153C"
                     /note="Protein containing an N-terminal epsin-like domain;
                     involved in clathrin recruitment and traffic between the
                     Golgi and endosomes; associates with the clathrin adaptor
                     Gga2p, clathrin adaptor complex AP-1, and clathrin"
                     /codon_start=1
                     /product="Ent5p"
                     /protein_id="NP_010437.3"
                     /db_xref="GI:398365867"
                     /db_xref="SGD:S000002560"
                     /db_xref="GeneID:851731"
                     /translation="MDSLSKKIQNLGIHDIRNAARFAQNVIVQYEPYQIDIRRATNTD
                     AWGPTPKHLAKVLRNRYQVPLYLMTEYTLKRLVDHIATRPKNLYEKARKDYVNYGSEW
                     RVVLKCLVVIEFLLLNVDTGDELNQIRSCLLTHKHILTREIAQFKVKFSNDGKMEIHE
                     RGIRKKGELILQYLEDSQFLKKERAKNKKNALKIRQQGESSIYNANQISTSASYDNID
                     DDEFDADADGFDSEMDANNVTNFNVPVETEANSNTRRRSHMEEQRRQRREILREQIKN
                     KEQQRKRKQQQDSIPDLIDLDDSTSTTNNITIDNGNNDNKNNNINSNSDDDDDEFGDF
                     QSETSPDTTAPKTSNSKIDDLLDWDGPKSDTDTTAAAQTSLPFAEKKQQKARPQATKD
                     KSKGNDAFSDLFSYSKSLV"
     gene            complement(<768512..>769000)
                     /gene="CPR1"
                     /locus_tag="YDR155C"
                     /gene_synonym="CPH1; CYP1"
                     /db_xref="GeneID:851733"
     mRNA            complement(<768512..>769000)
                     /gene="CPR1"
                     /locus_tag="YDR155C"
                     /gene_synonym="CPH1; CYP1"
                     /product="peptidylprolyl isomerase CPR1"
                     /transcript_id="NM_001180462.1"
                     /db_xref="GI:296143504"
                     /db_xref="GeneID:851733"
     CDS             complement(768512..769000)
                     /gene="CPR1"
                     /locus_tag="YDR155C"
                     /gene_synonym="CPH1; CYP1"
                     /EC_number="5.2.1.8"
                     /note="Cytoplasmic peptidyl-prolyl cis-trans isomerase
                     (cyclophilin); catalyzes the cis-trans isomerization of
                     peptide bonds N-terminal to proline residues; binds the
                     drug cyclosporin A; N-terminally propionylated in vivo;
                     protein abundance increases in response to DNA replication
                     stress"
                     /codon_start=1
                     /product="peptidylprolyl isomerase CPR1"
                     /protein_id="NP_010439.1"
                     /db_xref="GI:6320359"
                     /db_xref="SGD:S000002562"
                     /db_xref="GeneID:851733"
                     /translation="MSQVYFDVEADGQPIGRVVFKLYNDIVPKTAENFRALCTGEKGF
                     GYAGSPFHRVIPDFMLQGGDFTAGNGTGGKSIYGGKFPDENFKKHHDRPGLLSMANAG
                     PNTNGSQFFITTVPCPWLDGKHVVFGEVVDGYDIVKKVESLGSPSGATKARIVVAKSG
                     EL"
     gene            <769525..>769938
                     /gene="RPA14"
                     /locus_tag="YDR156W"
                     /db_xref="GeneID:851734"
     mRNA            <769525..>769938
                     /gene="RPA14"
                     /locus_tag="YDR156W"
                     /product="DNA-directed RNA polymerase I subunit RPA14"
                     /transcript_id="NM_001180463.1"
                     /db_xref="GI:296143505"
                     /db_xref="GeneID:851734"
     CDS             769525..769938
                     /gene="RPA14"
                     /locus_tag="YDR156W"
                     /note="RNA polymerase I subunit A14"
                     /codon_start=1
                     /product="DNA-directed RNA polymerase I subunit RPA14"
                     /protein_id="NP_010440.1"
                     /db_xref="GI:6320360"
                     /db_xref="SGD:S000002563"
                     /db_xref="GeneID:851734"
                     /translation="MMKGSRRTGNNTATTLNTPVVIHATQLPQHVSTDEVLQFLESFI
                     DEKENIIDSTTMNTISGNAADADAAAVANTSLNIDTNLSSSISQLKRIQRDFKGLPPA
                     QDFSAAPIQVSTTEKKETSIGVSATGGKKTTFADE"
     gene            <770357..>771454
                     /gene="HOM2"
                     /locus_tag="YDR158W"
                     /gene_synonym="THR2"
                     /db_xref="GeneID:851736"
     mRNA            <770357..>771454
                     /gene="HOM2"
                     /locus_tag="YDR158W"
                     /gene_synonym="THR2"
                     /product="aspartate-semialdehyde dehydrogenase"
                     /transcript_id="NM_001180465.3"
                     /db_xref="GI:398365876"
                     /db_xref="GeneID:851736"
     CDS             770357..771454
                     /gene="HOM2"
                     /locus_tag="YDR158W"
                     /gene_synonym="THR2"
                     /EC_number="1.2.1.11"
                     /note="Aspartic beta semi-aldehyde dehydrogenase;
                     catalyzes the second step in the common pathway for
                     methionine and threonine biosynthesis; expression
                     regulated by Gcn4p and the general control of amino acid
                     synthesis"
                     /codon_start=1
                     /product="aspartate-semialdehyde dehydrogenase"
                     /protein_id="NP_010442.3"
                     /db_xref="GI:398365877"
                     /db_xref="SGD:S000002565"
                     /db_xref="GeneID:851736"
                     /translation="MAGKKIAGVLGATGSVGQRFILLLANHPHFELKVLGASSRSAGK
                     KYVDAVNWKQTDLLPESATDIIVSECKSEFFKECDIVFSGLDADYAGAIEKEFMEAGI
                     AIVSNAKNYRREQDVPLIVPVVNPEHLDIVAQKLDTAKAQGKPRPGFIICISNCSTAG
                     LVAPLKPLIEKFGPIDALTTTTLQAISGAGFSPGVPGIDILDNIIPYIGGEEDKMEWE
                     TKKILAPLAEDKTHVKLLTPEEIKVSAQCNRVAVSDGHTECISLRFKNRPAPSVEQVK
                     TCLKEYVCDAYKLGCHSAPKQTIHVLEQPDRPQPRLDRNRDSGYGVSVGRIREDPLLD
                     FKMVVLSHNTIIGAAGSGVLIAEILLARNLI"
     gene            <771877..>775782
                     /gene="SAC3"
                     /locus_tag="YDR159W"
                     /gene_synonym="LEP1"
                     /db_xref="GeneID:851737"
     mRNA            <771877..>775782
                     /gene="SAC3"
                     /locus_tag="YDR159W"
                     /gene_synonym="LEP1"
                     /product="Sac3p"
                     /transcript_id="NM_001180466.3"
                     /db_xref="GI:398365882"
                     /db_xref="GeneID:851737"
     CDS             771877..775782
                     /gene="SAC3"
                     /locus_tag="YDR159W"
                     /gene_synonym="LEP1"
                     /note="mRNA export factor; required for biogenesis of the
                     small ribosomal subunit; component of TREX-2 complex
                     (Sac3p-Thp1p-Sus1p-Cdc31p) involved in transcription
                     elongation and mRNA export from the nucleus; involved in
                     post-transcriptional tethering of active genes to the
                     nuclear periphery and to non-nascent mRNP; similar to the
                     human germinal center-associated nuclear protein (GANP)"
                     /codon_start=1
                     /product="Sac3p"
                     /protein_id="NP_010443.3"
                     /db_xref="GI:398365883"
                     /db_xref="SGD:S000002566"
                     /db_xref="GeneID:851737"
                     /translation="MNTSFGSVVPSTNFNFFKGHGNNDNTSANSTVNNSNFFLNSNET
                     KPSKNVFMVHSTSQKKSQQPLQNLSHSPSYTENKPDKKKKYMINDAKTIQLVGPLISS
                     PDNLGFQKRSHKARELPRFLINQEPQLEKRAFVQDPWDKANQEKMISLEESIDDLNEL
                     YETLKKMRNTERSIMEEKGLVDKADSAKDLYDAIVFQGTCLDMCPTFERSRRNVEYTV
                     YSYEKNQPNDKKASRTKALKVFARPAAAAAPPLPSDVRPPHILVKTLDYIVDNLLTTL
                     PESEGFLWDRMRSIRQDFTYQNYSGPEAVDCNERIVRIHLLILHIMVKSNVEFSLQQE
                     LEQLHKSLITLSEIYDDVRSSGGTCPNEAEFRAYALLSKIRDPQYDENIQRLPKHIFQ
                     DKLVQMALCFRRVISNSAYTERGFVKTENCLNFYARFFQLMQSPSLPLLMGFFLQMHL
                     TDIRFYALRALSHTLNKKHKPIPFIYLENMLLFNNRQEIIEFCNYYSIEIINGDAADL
                     KTLQHYSHKLSETQPLKKTYLTCLERRLQKTTYKGLINGGEDNLASSVYVKDPKKDRI
                     PSIADQSFLMENFQNNYNEKLNQNSSVKPQINTSPKRVATRPNHFPFSQESKQLPQIS
                     QSHTLSTNPLLTPQVHGDLSEQKQQQIKTVTDGGSPFVFDQSAQNSTVEASKAHMIST
                     TSNGAYDEKLSSEQEEMRKKEEQRIEEEKTQLKKKQENADKQVITEQIANDLVKEVVN
                     SSVISIVKREFSEANYRKDFIDTMTRELYDAFLHERLYLIYMDSRAELKRNSTLKKKF
                     FEKWQASYSQAKKNRILEEKKREEIKLVSHQLGVPGFKKSTCLFRTPYKGNVNSSFML
                     SSSDKNLIFSPVNDEFNKFATHLTKISKLWRPLEMQSIYYDNLTKKFPSNSLTPANLF
                     IYAKDWTSLSNRWILSKFNLQTAQDSKKFSNNIISSRIICIDDEYEPSDFSDLQLLIF
                     NTGVTNPDIFDLEMKLKDDGEELIKLITGISLNTNICFSLLIIYWESAENTLSESTIK
                     HLLKLNRISKNYSSVIERIDLMNLTEESPHKCLEDKLSEISHSYVYKLTERGKYDKTL
                     RQKRSLAGIHSRSTQLQTTKDIDQKMKKMLEKEKNKYQQQIGERNTYAHLESHIDASP
                     RSKKRKLPILLSTSHSSQFKTPLASRLNTSGSSTSPPLPSHLAMKFRKNSRVTSLHTV
                     LPVSTPSHSNNIPAASFSGNNTTDIQSQQLIENQKSTSVYLNNVSERILGNQEICQTP
                     INPVTPVLDGADQGKEDIPDSILELKILIDSVKKKVNND"
     gene            <776163..>778721
                     /gene="SSY1"
                     /locus_tag="YDR160W"
                     /gene_synonym="RAA1; SHR10"
                     /db_xref="GeneID:851738"
     mRNA            <776163..>778721
                     /gene="SSY1"
                     /locus_tag="YDR160W"
                     /gene_synonym="RAA1; SHR10"
                     /product="Ssy1p"
                     /transcript_id="NM_001180467.1"
                     /db_xref="GI:296143508"
                     /db_xref="GeneID:851738"
     CDS             776163..778721
                     /gene="SSY1"
                     /locus_tag="YDR160W"
                     /gene_synonym="RAA1; SHR10"
                     /note="Component of the SPS plasma membrane amino acid
                     sensor system; senses external amino acid concentration
                     and transmits intracellular signals that result in
                     regulation of expression of amino acid permease genes;
                     other members are Ssy1p, Ptr3p, and Ssy5p"
                     /codon_start=1
                     /product="Ssy1p"
                     /protein_id="NP_010444.1"
                     /db_xref="GI:6320364"
                     /db_xref="SGD:S000002567"
                     /db_xref="GeneID:851738"
                     /translation="MSSVNQIYDLFPNKHNIQFTDSHSQEHDTSSSLAKNDTDGTISI
                     PGSIDTGILKSIIEEQGWNDAELYRSSIQNQRFFLTDKYTKKKHLTMEDMLSPEEEQI
                     YQEPIQDFQTYNKRVQREYELRERMEEFFRQNTKNDLHILNEDSLNQQYSPLGPADYV
                     LPLDRYSRMKHIASNFFRKKLGIPRKLKRRSHYNPNAEGHTKGNSSILSSTTDVIDNA
                     SYRNIAIDENVDITHKEHAIDEINEQGASGSESVVEGGSLLHDIEKVFNRSRATRKYH
                     IQRKLKVRHIQMLSIGACFSVGLFLTSGKAFSIAGPFGTLLGFGLTGSIILATMLSFT
                     ELSTLIPVSSGFSGLASRFVEDAFGFALGWTYWISCMLALPAQVSSSTFYLSYYNNVN
                     ISKGVTAGFITLFSAFSIVVNLLDVSIMGEIVYVAGISKVIIAILMVFTMIILNAGHG
                     NDIHEGVGFRYWDSSKSVRNLTYGLYRPTFDLADAGEGSKKGISGPKGRFLATASVML
                     ISTFAFSGVEMTFLASGEAINPRKTIPSATKRTFSIVLISYVFLIFSVGINIYSGDPR
                     LLSYFPGISEKRYEAIIKGTGMDWRLRTNCRGGIDYRQISVGTGYSSPWVVALQNFGL
                     CTFASAFNAILIFFTATAGISSLFSCSRTLYAMSVQRKAPPVFEICSKRGVPYVSVIF
                     SSLFSVIAYIAVDQTAIENFDVLANVSSASTSIIWMGLNLSFLRFYYALKQRKDIISR
                     NDSSYPYKSPFQPYLAIYGLVGCSLFVIFMGYPNFIHHFWSTKAFFSAYGGLMFFFIS
                     YTAYKVLGTSKIQRLDQLDMDSGRREMDRTDWTEHSQYLGTYRERAKKLVTWLI"
     gene            <779043..>780206
                     /locus_tag="YDR161W"
                     /db_xref="GeneID:851739"
     mRNA            <779043..>780206
                     /locus_tag="YDR161W"
                     /product="hypothetical protein"
                     /transcript_id="NM_001180468.1"
                     /db_xref="GI:296143509"
                     /db_xref="GeneID:851739"
     CDS             779043..780206
                     /locus_tag="YDR161W"
                     /note="hypothetical protein; non-essential gene; proposed
                     function in rRNA and ribosome biosynthesis based on
                     transcriptional co-regulation; genetic interactions
                     suggest a role in ER-associated protein degradation
                     (ERAD)"
                     /codon_start=1
                     /product="hypothetical protein"
                     /protein_id="NP_010445.1"
                     /db_xref="GI:6320365"
                     /db_xref="SGD:S000002568"
                     /db_xref="GeneID:851739"
                     /translation="MSELEATIRQAKEALAENNAKKALKILKPFKSSLKKENANNVIL
                     NEVFADAYLDNGQVEKAYPILARACELDPEGQVGGPDKFFTMGQIMGGQDGVSIITRG
                     IMNISNTGGEMLTNVQVEKIVGGLLSVIEIWMTDLCMEPNAEEQCEELIQKAMELTEG
                     KSPETWSTLGSIKISQQKFGEAYEAFSQAWNFFELKKQEIGSGINENGDTTQKAGLQS
                     EYVDLLQPLLSLTKMCLEVGAYEVALKVIAAVRDIDEDNIEGYYLEGFTYYLMSKLEI
                     FKLNNPEVSLRPENIYEFNQLIQEVPLDLSHEPISQLIYDSRLALSFALQAGVNADSK
                     DEIVQELLGGANALLQEIGGPLDPSELTQIKKGDLVNENEDLEELDIEEEYSD"
     gene            complement(<780390..>781100)
                     /gene="NBP2"
                     /locus_tag="YDR162C"
                     /db_xref="GeneID:851740"
     mRNA            complement(<780390..>781100)
                     /gene="NBP2"
                     /locus_tag="YDR162C"
                     /product="Nbp2p"
                     /transcript_id="NM_001180469.3"
                     /db_xref="GI:398365894"
                     /db_xref="GeneID:851740"
     CDS             complement(780390..781100)
                     /gene="NBP2"
                     /locus_tag="YDR162C"
                     /note="Protein involved in the HOG (high osmolarity
                     glycerol) pathway; negatively regulates Hog1p by
                     recruitment of phosphatase Ptc1p the Pbs2p-Hog1p complex;
                     interacts with Bck1p and down regulates the cell wall
                     integrity pathway; found in the nucleus and cytoplasm,
                     contains an SH3 domain and a Ptc1p binding domain (PBM)"
                     /codon_start=1
                     /product="Nbp2p"
                     /protein_id="NP_010446.3"
                     /db_xref="GI:398365895"
                     /db_xref="SGD:S000002569"
                     /db_xref="GeneID:851740"
                     /translation="MATMETTTQKDTNILKSGLKKTIGVLNEAVLQNGREVEAVQAGN
                     SDTMEDTETTTIGYISIKDYAYADSNPLHYGYFDGDNEEDEMVSDSSNGEDTYNKRQS
                     ITLPDDYIVNQRAVALYDFEPENDNELRLAEGDIVFISYKHGQGWLVAENESGSKTGL
                     VPEEFVSYIQPEDGENEVENKARPFYLTHLITQSVSPKNNIDNTNEDEYDDNDEWEDI
                     DDVAEVEADMKTKLDISD"
     gene            <781423..>781950
                     /gene="CWC15"
                     /locus_tag="YDR163W"
                     /db_xref="GeneID:851741"
     mRNA            <781423..>781950
                     /gene="CWC15"
                     /locus_tag="YDR163W"
                     /product="Cwc15p"
                     /transcript_id="NM_001180470.3"
                     /db_xref="GI:398365896"
                     /db_xref="GeneID:851741"
     CDS             781423..781950
                     /gene="CWC15"
                     /locus_tag="YDR163W"
                     /note="Non-essential protein involved in pre-mRNA
                     splicing; component of a complex containing Cef1p; has
                     similarity to S. pombe Cwf15p"
                     /codon_start=1
                     /product="Cwc15p"
                     /protein_id="NP_010447.3"
                     /db_xref="GI:398365897"
                     /db_xref="SGD:S000002570"
                     /db_xref="GeneID:851741"
                     /translation="MTTSHRPQLEARSGAKAAAYTPTGIEHARLLPGHTTLKYRKFKE
                     EENLRANCAQEDRSNDKSLEEAVMNEEKQDVVGSGNLQETRSEKDQKDSLQELLVTQK
                     NKVEDKAELEGNEQLKGGNSSRRSWRKGTAFGRHKVTKETNIKEHATKKSASGYINDM
                     TKSEYHQEFLHKHVR"
     gene            complement(<782041..>784215)
                     /gene="SEC1"
                     /locus_tag="YDR164C"
                     /db_xref="GeneID:851742"
     mRNA            complement(<782041..>784215)
                     /gene="SEC1"
                     /locus_tag="YDR164C"
                     /product="Sec1p"
                     /transcript_id="NM_001180471.1"
                     /db_xref="GI:296143512"
                     /db_xref="GeneID:851742"
     CDS             complement(782041..784215)
                     /gene="SEC1"
                     /locus_tag="YDR164C"
                     /note="Sm-like protein involved in docking and fusion of
                     exocytic vesicles; binds to assembled SNARE complexes at
                     the membrane and stimulates membrane fusion; localization
                     to sites of secretion (bud neck and bud tip) is dependent
                     on SNARE function; interacts directly with essential
                     exocyst subunit Sec6p"
                     /codon_start=1
                     /product="Sec1p"
                     /protein_id="NP_010448.1"
                     /db_xref="GI:6320368"
                     /db_xref="SGD:S000002571"
                     /db_xref="GeneID:851742"
                     /translation="MSDLIELQRNYLIGVLNQIETKNNLKFLIIDKTVETILSYLFLT
                     PQELLNNVTSVDLIDSPTRKGQSSIEAIYILEPTKYNINCIDADFMVRPPKYRRCHIR
                     FLPGLTNPIFQFFQSKRYIAQNLESFKPIELGFFVKESQFFETLQMEHSLQVFFNNNC
                     KALIPTNVRKIVGSLVSLCVITGEYPIVRYSVSNPVEEEDARNGNAVVNANSLTRSIA
                     NAFQIAIDTYARNNPDFPPQNTERPRSILIITDRTLDPFAPILHDFSYQAMAYDLVAN
                     VDTQKDIYHYSAENEAGEQEEKVSKLVDLYDPDWIDLKHQHIMDANEYIQGRIKELIA
                     KNPLLVDRSNVKNTTDLLSVVAHLKDFDEERRRLILHKTLVDECLGENAERKLADISA
                     IEQNLSGFGMDFSGEKIKHIIDDLLPALAMKEPTILDKLRYIIAYALFRGGIIELDFI
                     KLLNFIGVTHEHENFQQYLKIFRNYDLIDFKLIKDKPKDKPFQKEWFHDTLVNDPNIY
                     HTSRFVPAVGNILSKVIANPLLLSEQYFPYLKDKPIELLNEEEFQAGLANTSANSSSS
                     LRNPRHKAAWTTKSSNIKKNIPRQRFFYYVIGGISIPEIKAAYDQSNLKNRDIFIGSD
                     EILTPTKFLDEVERLQNPREFFKFKEDQRQQVNPPDFLLREMKPVAQPVSHVHLKSQD
                     NSPKSGTSSPKAAGSLKSEPPEKEKKRSKFSRFLKRKSHHDK"
     gene            <784871..>786205
                     /gene="TRM82"
                     /locus_tag="YDR165W"
                     /db_xref="GeneID:851743"
     mRNA            <784871..>786205
                     /gene="TRM82"
                     /locus_tag="YDR165W"
                     /product="Trm82p"
                     /transcript_id="NM_001180472.1"
                     /db_xref="GI:296143513"
                     /db_xref="GeneID:851743"
     CDS             784871..786205
                     /gene="TRM82"
                     /locus_tag="YDR165W"
                     /note="Catalytic subunit of a tRNA methyltransferase
                     complex; Trm8p and Trm82p comprise an enzyme that
                     catalyzes a methyl-transfer from S-adenosyl-l-methionine
                     to the N(7) atom of guanine at position 46 in tRNA; Trm8
                     lacks catalytic activity if not bound to Trm82p;
                     relocalizes to the cytosol in response to hypoxia"
                     /codon_start=1
                     /product="Trm82p"
                     /protein_id="NP_010449.1"
                     /db_xref="GI:6320369"
                     /db_xref="SGD:S000002572"
                     /db_xref="GeneID:851743"
                     /translation="MSVIHPLQNLLTSRDGSLVFAIIKNCILSFKYQSPNHWEFAGKW
                     SDDFDKIQESRNTTAKEQQGQSSENENENKKLKSNKGDSIKRTAAKVPSPGLGAPPIY
                     SYIRNLRLTSDESRLIACADSDKSLLVFDVDKTSKNVLKLRKRFCFSKRPNAISIAED
                     DTTVIIADKFGDVYSIDINSIPEEKFTQEPILGHVSMLTDVHLIKDSDGHQFIITSDR
                     DEHIKISHYPQCFIVDKWLFGHKHFVSSICCGKDYLLLSAGGDDKIFAWDWKTGKNLS
                     TFDYNSLIKPYLNDQHLAPPRFQNENNDIIEFAVSKIIKSKNLPFVAFFVEATKCIII
                     LEMSEKQKGDLALKQIITFPYNVISLSAHNDEFQVTLDNKESSGVQKNFAKFIEYNLN
                     ENSFVVNNEKSNEFDSAIIQSVQGDSNLVTKKEEIYPLYNVSSLRKHGEHYS"
     gene            complement(<786306..>789221)
                     /gene="SEC5"
                     /locus_tag="YDR166C"
                     /db_xref="GeneID:851744"
     mRNA            complement(<786306..>789221)
                     /gene="SEC5"
                     /locus_tag="YDR166C"
                     /product="Sec5p"
                     /transcript_id="NM_001180473.3"
                     /db_xref="GI:398365918"
                     /db_xref="GeneID:851744"
     CDS             complement(786306..789221)
                     /gene="SEC5"
                     /locus_tag="YDR166C"
                     /note="Essential 107kDa subunit of the exocyst complex;
                     the exocyst mediates polarized targeting and tethering of
                     post-Golgi secretory vesicles to active sites of
                     exocytosis at the plasma membrane prior to SNARE-mediated
                     fusion; involved in assembly of the exocyst complex;
                     required with Sec3p for ER inheritance where it promotes
                     anchoring of the cortical ER at the bud tip"
                     /codon_start=1
                     /product="Sec5p"
                     /protein_id="NP_010450.3"
                     /db_xref="GI:398365919"
                     /db_xref="SGD:S000002573"
                     /db_xref="GeneID:851744"
                     /translation="MDRFQIGDEQLLRFYQLKTINPTHSWAQDSSKLNNEEATSNELG
                     VETSFDILKDFKYGNQISIDKESRAYLNDESLSYIRDPLNGQEMSKELQHLPNDSMRL
                     NYLVNSKQFNVKAFLRDMHKQDSFNDLNNSLDRLDSDIQDQSIHLKQLVGKNFTKYVK
                     IKNKLDQIYKEFDEKTNEKNQCDSPKENQINVESLNKKVDEVIRTTTFKLKPLMDNYQ
                     KILNYQATKKFIELNKFYFNLPKSLKRCLTNNDFNEFIIEYSKGLTLRRRFNQSSDAS
                     QSLVIKRIWTQIENLLVTYKDLIWNSLINSNFNIDQPQETILSLFSKLLNLENFINNN
                     QRESESGNKNTTSSSNENPILRWMSIKMNGFQNELNELSGHMISKIIHSQRLILQNNT
                     NQDKSQGCVELSYYLKINQLFQIISDTGKDSEGLKSTVEPNKVNTISGTSYLNLNCQP
                     SSQGLTDSPTIIEMWLLILKYINDLWKICDQFIEFWEHIEKFLDGTYQNSIINEKRKE
                     NILIGDSNIIESYQKSLILKEEQINEVRLKGEEFITSVSQNLISFFTSSQSSLPSSLK
                     DSTGDITRSNKDSGSPLDYGFIPPNCNGLSCLRYLPKIVEPILKFSTELAQLNITTNG
                     ITICRNTLSTIINRCVGAISSTKLRDISNFYQLENWQVYETVTFSSKSQDSSKNLTFE
                     YGVTQFPEIVTSFQEVSIKTTRDLLFAYEKLPIINGISVVSYPSKQLLTGIEIQQIIS
                     MEAVLEAILKNAAKDKDNPRNSHTILTLTNLQYFRECAFPNILQYFDDAFEWNLASKN
                     LELFSLLSKMESSIFGNYLSDLKINLRDTLEEKFHEINWPMYTSNSFRVGDYIIEALM
                     ILIVVHSECFRIGPQLIHKILIETQIFIARYLFEAFKPYVGNLSNDGSLQIIVDLEFF
                     QKVMGPLLEKDTEATLRACLQNCFQNDTNRLQKCINEINPIVSANLKRTAIQFAAFS"
     gene            <789449..>790069
                     /gene="TAF10"
                     /locus_tag="YDR167W"
                     /gene_synonym="TAF23; TAF25"
                     /db_xref="GeneID:851745"
     mRNA            <789449..>790069
                     /gene="TAF10"
                     /locus_tag="YDR167W"
                     /gene_synonym="TAF23; TAF25"
                     /product="Taf10p"
                     /transcript_id="NM_001180474.3"
                     /db_xref="GI:398365920"
                     /db_xref="GeneID:851745"
     CDS             789449..790069
                     /gene="TAF10"
                     /locus_tag="YDR167W"
                     /gene_synonym="TAF23; TAF25"
                     /note="Subunit (145 kDa) of TFIID and SAGA complexes;
                     involved in RNA polymerase II transcription initiation and
                     in chromatin modification"
                     /codon_start=1
                     /product="Taf10p"
                     /protein_id="NP_010451.3"
                     /db_xref="GI:398365921"
                     /db_xref="SGD:S000002574"
                     /db_xref="GeneID:851745"
                     /translation="MDFEEDYDAEFDDNQEGQLETPFPSVAGADDGDNDNDDSVAENM
                     KKKQKREAVVDDGSENAFGIPEFTRKDKTLEEILEMMDSTPPIIPDAVIDYYLTKNGF
                     NVADVRVKRLLALATQKFVSDIAKDAYEYSRIRSSVAVSNANNSQARARQLLQGQQQP
                     GVQQISQQQHQQNEKTTASKVVLTVNDLSSAVAEYGLNIGRPDFYR"
     gene            <790328..>791848
                     /gene="CDC37"
                     /locus_tag="YDR168W"
                     /gene_synonym="SMO1"
                     /db_xref="GeneID:851746"
     mRNA            <790328..>791848
                     /gene="CDC37"
                     /locus_tag="YDR168W"
                     /gene_synonym="SMO1"
                     /product="Cdc37p"
                     /transcript_id="NM_001180475.1"
                     /db_xref="GI:296143516"
                     /db_xref="GeneID:851746"
     CDS             790328..791848
                     /gene="CDC37"
                     /locus_tag="YDR168W"
                     /gene_synonym="SMO1"
                     /note="Essential Hsp90p co-chaperone; necessary for
                     passage through the START phase of the cell cycle;
                     stabilizes protein kinase nascent chains and participates
                     along with Hsp90p in their folding"
                     /codon_start=1
                     /product="Cdc37p"
                     /protein_id="NP_010452.1"
                     /db_xref="GI:6320372"
                     /db_xref="SGD:S000002575"
                     /db_xref="GeneID:851746"
                     /translation="MAIDYSKWDKIELSDDSDVEVHPNVDKKSFIKWKQQSIHEQRFK
                     RNQDIKNLETQVDMYSHLNKRVDRILSNLPESSLTDLPAVTKFLNANFDKMEKSKGEN
                     VDPEIATYNEMVEDLFEQLAKDLDKEGKDSKSPSLIRDAILKHRAKIDSVTVEAKKKL
                     DELYKEKNAHISSEDIHTGFDSSFMNKQKGGAKPLEATPSEALSSAAESNILNKLAKS
                     SVPQTFIDFKDDPMKLAKETEEFGKISINEYSKSQKFLLEHLPIISEQQKDALMMKAF
                     EYQLHGDDKMTLQVIHQSELMAYIKEIYDMKKIPYLNPMELSNVINMFFEKVIFNKDK
                     PMGKESFLRSVQEKFLHIQKRSKILQQEEMDESNAEGVETIQLKSLDDSTELEVNLPD
                     FNSKDPEEMKKVKVFKTLIPEKMQEAIMTKNLDNINKVFEDIPIEEAEKLLEVFNDID
                     IIGIKAILENEKDFQSLKDQYEQDHEDATMENLSLNDRDGGGDNHEEVKHTADTVD"
     gene            complement(<792348..>793889)
                     /gene="STB3"
                     /locus_tag="YDR169C"
                     /db_xref="GeneID:851747"
     mRNA            complement(<792348..>793889)
                     /gene="STB3"
                     /locus_tag="YDR169C"
                     /product="Stb3p"
                     /transcript_id="NM_001180476.1"
                     /db_xref="GI:296143517"
                     /db_xref="GeneID:851747"
     CDS             complement(792348..793889)
                     /gene="STB3"
                     /locus_tag="YDR169C"
                     /note="Ribosomal RNA processing element (RRPE)-binding
                     protein; involved in the glucose-induced transition from
                     quiescence to growth; restricted to nucleus in quiescent
                     cells, released into cytoplasm after glucose repletion;
                     binds Sin3p; relative distribution to the nucleus
                     increases upon DNA replication stress"
                     /codon_start=1
                     /product="Stb3p"
                     /protein_id="NP_010453.1"
                     /db_xref="GI:6320373"
                     /db_xref="SGD:S000002576"
                     /db_xref="GeneID:851747"
                     /translation="MSENQKEVSPPQAISVKSEASSSIFSKPISTSSPAGLAAAQRVT
                     PGKLSTLLLEMGPLAIRHITQTLCLDIPCFKDLSSSKQRRLIMSAMESGDKEKSVVFE
                     KIGWGQWSAKRVDPANFDKELEATNFANAKVKDLISQESQRRKSNNSNSNSGGKVEMP
                     MKVEHNITNIDGATTPPTAVASTTIPVNIKRSKSPLAAANVVYIDENALASEDEDEEF
                     DEDDHHLHYQNKSRNSSNNFGKSSNGDPYSFGRRRSQVVFADSTPENIEHEIIAQKIR
                     PLLRNRRRSSIKPHTPFISKLNTHQDSSYLSPNTTSTTTPSNNNSNSNQAKIDLEKLT
                     ATSEPTSRRASRLSVSKESSIRSTLFPNKNYLIVTTNPNSKATSVSTSPKLEEQMNVS
                     SNPIVLSDKEKHRVASQHLNGESSPQLVPHSHHQPHSDTDEEDWESIGAASLRNNSLA
                     PNIDSVASSTNGVVSPKPTNPSFTNSQNGDIEPPLQHDQQKHEQQPRNGEDNSAAFLL
                     MSLKS"
     gene            complement(<794574..>794723)
                     /locus_tag="YDR169C-A"
                     /db_xref="GeneID:1466433"
     mRNA            complement(<794574..>794723)
                     /locus_tag="YDR169C-A"
                     /product="hypothetical protein"
                     /transcript_id="NM_001184544.3"
                     /db_xref="GI:398365936"
                     /db_xref="GeneID:1466433"
     CDS             complement(794574..794723)
                     /locus_tag="YDR169C-A"
                     /note="hypothetical protein; identified by fungal homology
                     and RT-PCR"
                     /codon_start=1
                     /product="hypothetical protein"
                     /protein_id="NP_878062.3"
                     /db_xref="GI:398365937"
                     /db_xref="SGD:S000028538"
                     /db_xref="GeneID:1466433"
                     /translation="MMRMSLKQMQSQRFSATSRVRMLLIGASGLRSSSSKLECPRFSN
                     KHGRN"
     gene            complement(<796193..>802222)
                     /gene="SEC7"
                     /locus_tag="YDR170C"
                     /db_xref="GeneID:851748"
     mRNA            complement(<796193..>802222)
                     /gene="SEC7"
                     /locus_tag="YDR170C"
                     /product="Sec7p"
                     /transcript_id="NM_001180477.3"
                     /db_xref="GI:398365940"
                     /db_xref="GeneID:851748"
     CDS             complement(796193..802222)
                     /gene="SEC7"
                     /locus_tag="YDR170C"
                     /note="Guanine nucleotide exchange factor (GEF) for ADP
                     ribosylation factors; involved in proliferation of the
                     Golgi, intra-Golgi transport and ER-to-Golgi transport;
                     found in the cytoplasm and on Golgi-associated coated
                     vesicles"
                     /codon_start=1
                     /product="Sec7p"
                     /protein_id="NP_010454.3"
                     /db_xref="GI:398365941"
                     /db_xref="SGD:S000002577"
                     /db_xref="GeneID:851748"
                     /translation="MSEQNSVVNAEKGDGEISSNVETASSVNPSVKPQNAIKEEAKET
                     NGEDQKCKGPENAGSTAETKETSNDATNGMKTPEETEDTNDKRHDDEGEDGDEDEDED
                     EDEDEDNGDEDDEDVDSSSSETSSEDGEDSESVSGESTESSSGEDEESDESDGNTSNS
                     SSGDESGSEEEEEEEEEEEEEENAGEPAIAHQDSVPTNDSTAPRSTHTRNISLSSNGS
                     NTNSTIILVKTTLETILNDKDIKKNSNAQKAIERTLQKFKEFDPQTTNNPHYVDSILV
                     FEALRASCRTKSSKVQSLALDCLSKLFSFRSLDETLLVNPPDSLASNDQRQDAADGIT
                     PPPKQKIIDAAIDTISDCFQGEGTDDRVELQIVRALSSCILEEDSSSLCHGASLLKAI
                     RTIYNVFVFSLNPSNQGIAQATLTQIISSVYDKIDLKQSTSSAVSLSTKNHQQQSAIE
                     LSEASENAETPAPLTLENMDKLNDDEERLMDAQQPDSIAITNQDLAVKDAFLVFRVMA
                     KICAKPLETELDMRSHAVRSKLLSLHIIYSIIKDHIDVFLSHNIFLPGKERVCFIDSI
                     RQYLRLVLSRNAASPLAPVFEVTLEIMWLLIANLRADFVKEIPVFLTEIYFPISELTT
                     STSQQKRYFLSVIQRICNDPRTLVEFYLNYDCNPGMPNVMEITVDYLTRLALTRVEIT
                     QTQRSYYDEQISKSLSTYNFSQLPLLTSSNLSSSPDVGQVNLLFPLDFALKMVSLNCI
                     VSVLRSLSSWAHKALNPNTHTANKVLLNTTSSARQESRSSLSNDVRSSIMTSNDDFKP
                     TYEDEESRSLSSQNIDADDPTQFENLKLRKTALSECIAIFNNKPKKAIPVLIKKGFLK
                     DDSPISIAKWLLETEGLDMAAVGDYLGEGDDKNIAIMHAFVDEFDFTGMSIVDALRSF
                     LQSFRLPGEGQKIDRFMLKFAERFVDQNPGVFSKADTAYVLSYSLIMLNTDLHSSQIK
                     NKMSLQEFLENNEGIDNGRDLPRDFLEGLFNEIANNEIKLISEQHQAMLSGDTNLVQQ
                     QQSAFNFFNSRDLTREAYNQVSKEISSKTELVFKNLNKNKGGPDVYYAASHVEHVKSI
                     FETLWMSFLAALTPPFKDYDDIDTTNKCLEGLKISIKIASTFRINDARTSFVGALVQF
                     CNLQNLEEIKVKNVNAMVILLEVALSEGNYLEGSWKDILLVVSQMERLQLISKGIDRD
                     TVPDVAQARVANPRVSYESSRSNNTSFFDVWGKKATPTELAQEKHHNQTLSPEISKFI
                     SSSELVVLMDNIFTKSSELSGNAIVDFIKALTAVSLEEIESSENASTPRMFSLQKMVD
                     VCYYNMDRIKLEWTPLWAVMGKAFNKIATNSNLAVVFFAIDSLRQLSMRFLDIEELSG
                     FEFQHDFLKPFEYTVQNSGNTEVQEMIIECFRNFILTKSESIKSGWKPILESLQYTAR
                     SSTESIVLKTQLLVSNDIVTNHFENVFSQEDAFSELVGVFREITKNKRFQKLSLHALE
                     SLRKMTQNVADICFYNENKTEEERKHNDALLRGKDIFQDVWFPMLFCFNDTIMTAEDL
                     EVRSRALNYMFDALVAYGGKFNDDFWEKICKKLLFPIFGVLSKHWEVNQFNSHDDLSV
                     WLSTTLIQALRNLIALFTHYFESLNRMLDGFLGLLVSCICQENDTIARIGRSCLQQLI
                     LQNVSKFNEYHWNQIGDVFDKLFDLTTANELFDYDPLQQGRKSSVSHHQTTNDTSQHS
                     DDDSNDRRENDSNISETVERAHQEESSEDVGGDMVETLNGQTKLNNGNSVPTVKDELN
                     PKPASLSIPKKTKHMKRNESNEDIRRRINIKNSIVVKCVLQLLMIELLNELFENEDFA
                     HCIPYKEAIRITRLLEKSYEFSRDFNEDYGLRTRLVEARVVDKIPNLLKQETSAAAVL
                     LDIMFQLYLNDDEKKADLITRLITICIQVVEGYVSLDDRTMERSINAWRSVIVEILQG
                     YYEFDDEDFRLYCPAMYALVIQILDKSVPTELRHAIKQFLSRVGELYLSTD"
     gene            complement(802731..802802)
                     /locus_tag="tQ(UUG)D3"
                     /db_xref="GeneID:851749"
     tRNA            complement(802731..802802)
                     /locus_tag="tQ(UUG)D3"
                     /product="tRNA-Gln"
                     /note="Glutamine tRNA (tRNA-Gln), predicted by tRNAscan-SE
                     analysis; thiolation of uridine at wobble position (34)
                     requires Ncs6p"
                     /db_xref="SGD:S000006695"
                     /db_xref="GeneID:851749"
     LTR             802905..803235
                     /note="Ty1 LTR"
                     /db_xref="SGD:S000006865"
     gene            <803195..>804517
                     /locus_tag="YDR170W-A"
                     /db_xref="GeneID:851750"
     mRNA            <803195..>804517
                     /locus_tag="YDR170W-A"
                     /product="gag protein"
                     /transcript_id="NM_001184320.1"
                     /db_xref="GI:296143520"
                     /db_xref="GeneID:851750"
     CDS             803195..804517
                     /locus_tag="YDR170W-A"
                     /note="Retrotransposon TYA Gag gene; Gag is a nucleocapsid
                     protein that is the structural constituent of virus-like
                     particles (VLPs); similar to retroviral Gag; YDR170W-A is
                     part of a mutant retrotransposon; distribution in the
                     cytoplasm becomes irregular rather than punctate upon DNA
                     replication stress"
                     /codon_start=1
                     /product="gag protein"
                     /protein_id="NP_010455.1"
                     /db_xref="GI:6320375"
                     /db_xref="SGD:S000007227"
                     /db_xref="GeneID:851750"
                     /translation="MESQQLSQHSPISHGSACASVTSKEVQTTQDPLDISASKTEECE
                     KVFTQANSQQPTTPPSAAVPENHHHASPQAAQVPLPQNGPYPQQRMMTPQQANISGWP
                     VYGHPSLMPYPPYQMSPMYAPPGAQSQFTQYPQYVGTHLNTPSPESGNSFPDSSSAKS
                     NMTSTNQHVRPPPILTSPNDFLNWVKIYIKFLQNSNLGDIIPTATRKAVRQMTDDELT
                     FLCHTFQLFALSQFLPTWVKDILSVDYTDIMKILSKSINKMQSDTQEVNDITTLANLH
                     YNGSTPADAFEAEVTNILDRLKNNGIPINNKVACQFIMRGLSGEYKFLRYARHRYIHM
                     TVADLFSDIHSMYEEQQESKRNKSTYRRSPSDEKKDSRTYTNTTKPKSITRNSQKPNN
                     SQSRTARAHNVSTSNNFPGPDNDLIRGSTTEPIQLKNKHDLHLRPGTY"
     rep_origin      806052..806277
                     /note="ARS425;
                     Autonomously Replicating Sequence"
                     /db_xref="SGD:S000118439"
     gene            <806621..>807748
                     /gene="HSP42"
                     /locus_tag="YDR171W"
                     /db_xref="GeneID:851751"
     mRNA            <806621..>807748
                     /gene="HSP42"
                     /locus_tag="YDR171W"
                     /product="Hsp42p"
                     /transcript_id="NM_001180478.1"
                     /db_xref="GI:296143521"
                     /db_xref="GeneID:851751"
     CDS             806621..807748
                     /gene="HSP42"
                     /locus_tag="YDR171W"
                     /note="Small heat shock protein (sHSP) with chaperone
                     activity; forms barrel-shaped oligomers that suppress
                     unfolded protein aggregation; involved in cytoskeleton
                     reorganization after heat shock; protein abundance
                     increases and forms cytoplasmic foci in response to DNA
                     replication stress"
                     /codon_start=1
                     /product="Hsp42p"
                     /protein_id="NP_010456.1"
                     /db_xref="GI:6320376"
                     /db_xref="SGD:S000002578"
                     /db_xref="GeneID:851751"
                     /translation="MSFYQPSLSLYDVLNALSNQTGQRGQQGYPRQPQRPQRYHPHYG
                     QVHVGGHHPRHHPLYSRYNGVPNTYYYQFPGQAYYYSPEYGYDDEDGEEEDQDEDMVG
                     DSGTTRQEDGGEDSNSRRYPSYYHCNTARNNRTNQQANSLNDLLTALIGVPPYEGTEP
                     EIEANTEQEGEKGEEKDKKDKSEAPKEEAGETNKEKPLNQLEESSRPPLAKKSSSFAH
                     LQAPSPIPDPLQVSKPETRMDLPFSPEVNVYDTEDTYVVVLALPGANSRAFHIDYHPS
                     SHEMLIKGKIEDRVGIDEKFLKITELKYGAFERTVKFPVLPRIKDEEIKATYNNGLLQ
                     IKVPKIVNDTEKPKPKKRIAIEEIPDEELEFEENPNPTVEN"
     gene            <808324..>810381
                     /gene="SUP35"
                     /locus_tag="YDR172W"
                     /gene_synonym="GST1; PNM2; SAL3; SUF12; SUP2; SUP36"
                     /db_xref="GeneID:851752"
     mRNA            <808324..>810381
                     /gene="SUP35"
                     /locus_tag="YDR172W"
                     /gene_synonym="GST1; PNM2; SAL3; SUF12; SUP2; SUP36"
                     /product="translation termination factor GTPase eRF3"
                     /transcript_id="NM_001180479.3"
                     /db_xref="GI:398365952"
                     /db_xref="GeneID:851752"
     CDS             808324..810381
                     /gene="SUP35"
                     /locus_tag="YDR172W"
                     /gene_synonym="GST1; PNM2; SAL3; SUF12; SUP2; SUP36"
                     /note="Translation termination factor eRF3; has a role in
                     mRNA deadenylation and decay; altered protein conformation
                     creates the [PSI(+)] prion that alters translational
                     fidelity and results in a nonsense suppressor phenotype"
                     /codon_start=1
                     /product="translation termination factor GTPase eRF3"
                     /protein_id="NP_010457.3"
                     /db_xref="GI:398365953"
                     /db_xref="SGD:S000002579"
                     /db_xref="GeneID:851752"
                     /translation="MSDSNQGNNQQNYQQYSQNGNQQQGNNRYQGYQAYNAQAQPAGG
                     YYQNYQGYSGYQQGGYQQYNPDAGYQQQYNPQGGYQQYNPQGGYQQQFNPQGGRGNYK
                     NFNYNNNLQGYQAGFQPQSQGMSLNDFQKQQKQAAPKPKKTLKLVSSSGIKLANATKK
                     VGTKPAESDKKEEEKSAETKEPTKEPTKVEEPVKKEEKPVQTEEKTEEKSELPKVEDL
                     KISESTHNTNNANVTSADALIKEQEEEVDDEVVNDMFGGKDHVSLIFMGHVDAGKSTM
                     GGNLLYLTGSVDKRTIEKYEREAKDAGRQGWYLSWVMDTNKEERNDGKTIEVGKAYFE
                     TEKRRYTILDAPGHKMYVSEMIGGASQADVGVLVISARKGEYETGFERGGQTREHALL
                     AKTQGVNKMVVVVNKMDDPTVNWSKERYDQCVSNVSNFLRAIGYNIKTDVVFMPVSGY
                     SGANLKDHVDPKECPWYTGPTLLEYLDTMNHVDRHINAPFMLPIAAKMKDLGTIVEGK
                     IESGHIKKGQSTLLMPNKTAVEIQNIYNETENEVDMAMCGEQVKLRIKGVEEEDISPG
                     FVLTSPKNPIKSVTKFVAQIAIVELKSIIAAGFSCVMHVHTAIEEVHIVKLLHKLEKG
                     TNRKSKKPPAFAKKGMKVIAVLETEAPVCVETYQDYPQLGRFTLRDQGTTIAIGKIVK
                     IAE"
     gene            complement(<810565..>811632)
                     /gene="ARG82"
                     /locus_tag="YDR173C"
                     /gene_synonym="ARGR3; IPK2"
                     /db_xref="GeneID:851753"
     mRNA            complement(<810565..>811632)
                     /gene="ARG82"
                     /locus_tag="YDR173C"
                     /gene_synonym="ARGR3; IPK2"
                     /product="inositol polyphosphate multikinase"
                     /transcript_id="NM_001180480.3"
                     /db_xref="GI:398365956"
                     /db_xref="GeneID:851753"
     CDS             complement(810565..811632)
                     /gene="ARG82"
                     /locus_tag="YDR173C"
                     /gene_synonym="ARGR3; IPK2"
                     /EC_number="2.7.1.151"
                     /note="Inositol polyphosphate multikinase (IPMK);
                     sequentially phosphorylates Ins(1,4,5)P3 to form
                     Ins(1,3,4,5,6)P5; also has diphosphoinositol polyphosphate
                     synthase activity; regulates arginine-, phosphate-, and
                     nitrogen-responsive genes"
                     /codon_start=1
                     /product="inositol polyphosphate multikinase"
                     /protein_id="NP_010458.3"
                     /db_xref="GI:398365957"
                     /db_xref="SGD:S000002580"
                     /db_xref="GeneID:851753"
                     /translation="MDTVNNYRVLEHKAAGHDGTLTDGDGLLIFKPAFPQELEFYKAI
                     QVRDVSRRKSSADGDAPLCSWMPTYLGVLNEGAKIEQSGDAALLKIDERLSDSTDNLD
                     SIPVKSEKSKQYLVLENLLYGFSKPNILDIKLGKTLYDSKASLEKRERMKRVSETTTS
                     GSLGFRICGMKIQKNPSVLNQLSLEYYEEEADSDYIFINKLYGRSRTDQNVSDAIELY
                     FNNPHLSDARKHQLKKTFLKRLQLFYNTMLEEEVRMISSSLLFIYEGDPERWELLNDV
                     DKLMRDDFIDDDDDDDDNDDDDDDDAEGSSEGPKDKKTTGSLSSMSLIDFAHSEITPG
                     KGYDENVIEGVETLLDIFMKF"
     gene            <812110..>812850
                     /gene="HMO1"
                     /locus_tag="YDR174W"
                     /gene_synonym="HSM2"
                     /db_xref="GeneID:851754"
     mRNA            <812110..>812850
                     /gene="HMO1"
                     /locus_tag="YDR174W"
                     /gene_synonym="HSM2"
                     /product="Hmo1p"
                     /transcript_id="NM_001180481.1"
                     /db_xref="GI:296143524"
                     /db_xref="GeneID:851754"
     CDS             812110..812850
                     /gene="HMO1"
                     /locus_tag="YDR174W"
                     /gene_synonym="HSM2"
                     /note="Chromatin associated high mobility group (HMG)
                     family member; involved in genome maintenance;
                     rDNA-binding component of the Pol I transcription system;
                     associates with a 5'-3' DNA helicase and Fpr1p, a prolyl
                     isomerase; relocalizes to the cytosol in response to
                     hypoxia"
                     /codon_start=1
                     /product="Hmo1p"
                     /protein_id="NP_010459.1"
                     /db_xref="GI:6320379"
                     /db_xref="SGD:S000002581"
                     /db_xref="GeneID:851754"
                     /translation="MTTDPSVKLKSAKDSLVSSLFELSKAANQTASSIVDFYNAIGDD
                     EEEKIEAFTTLTESLQTLTSGVNHLHGISSELVNPIDDDKDAIIAAPVKAVRRKIERD
                     PNAPKKPLTVFFAYSAYVRQELREDRQKAGLPPLSSTEITQEISKKWKELSDNEKEKW
                     KQAYNVELENYQREKSKYLEAKKNGTLPPASLENGPTHAPVPIPFSLQHAAEPPVEKR
                     PHDDDGSSEKKKKKKKKDKKKDKSNSSI"
     gene            complement(<813193..>814152)
                     /gene="RSM24"
                     /locus_tag="YDR175C"
                     /db_xref="GeneID:851755"
     mRNA            complement(<813193..>814152)
                     /gene="RSM24"
                     /locus_tag="YDR175C"
                     /product="mitochondrial 37S ribosomal protein RSM24"
                     /transcript_id="NM_001180482.1"
                     /db_xref="GI:296143525"
                     /db_xref="GeneID:851755"
     CDS             complement(813193..814152)
                     /gene="RSM24"
                     /locus_tag="YDR175C"
                     /note="Mitochondrial ribosomal protein of the small
                     subunit"
                     /codon_start=1
                     /product="mitochondrial 37S ribosomal protein RSM24"
                     /protein_id="NP_010460.1"
                     /db_xref="GI:6320380"
                     /db_xref="SGD:S000002582"
                     /db_xref="GeneID:851755"
                     /translation="MKVPLGLWKVSRGNLWSTQKRVLTMSRCLNSDAGNEAKTVREGP
                     AFSADLYMHPEKWKGLPPQRILELYWERMARLGSEYKPNKDELNALLTTSEYSNVPVN
                     DIKKLYHRGEQGAIDIKGGNVNRDNSLRPFMFDELPSQAQELVAQHREQRFYNRLAAY
                     ELPLLAQYRQEYKRPSPESHPVTYRYTSYVGEEHPNSRKVVLSVKTKELGLEEKSLHK
                     FRILARSRYDHTTDIFKMSSDKFEHASQNARYLHDILQRLLAESKDLTEDDFSDVPLD
                     TRHTIAKSLRKKKRDYEFPEHWKRPEDAPKKKFDIVDQLLSTL"
     gene            <814452..>816560
                     /gene="NGG1"
                     /locus_tag="YDR176W"
                     /gene_synonym="ADA3; SWI7"
                     /db_xref="GeneID:851756"
     mRNA            <814452..>816560
                     /gene="NGG1"
                     /locus_tag="YDR176W"
                     /gene_synonym="ADA3; SWI7"
                     /product="Ngg1p"
                     /transcript_id="NM_001180483.3"
                     /db_xref="GI:398365962"
                     /db_xref="GeneID:851756"
     CDS             814452..816560
                     /gene="NGG1"
                     /locus_tag="YDR176W"
                     /gene_synonym="ADA3; SWI7"
                     /note="Subunit of chromatin modifying histone
                     acetyltransferase complexes; member of the ADA complex,
                     the SAGA complex, and the SLIK complex; transcriptional
                     regulator involved in glucose repression of
                     Gal4p-regulated genes"
                     /codon_start=1
                     /product="Ngg1p"
                     /protein_id="NP_010461.3"
                     /db_xref="GI:398365963"
                     /db_xref="SGD:S000002583"
                     /db_xref="GeneID:851756"
                     /translation="MPRHGRRGKLPKGEKLPKKEGGDNTPSKLLSSMLKTLDLTFERD
                     IGMLNGKSVRSIPNKKTLLELQSQLDSLNEILGTIARGDQETIEALRKIRDSKNEKQA
                     NDEKQETSNADGQHESSTATEETNIIDKGVQSPPKPPPSNEISGTIENDVESIKQAAD
                     NMAKEEINEDKDLQVHRDQPREKRPFDSETENRATENENTQRPDNKKQKIDVDKMEND
                     PTVKNPKSEFVVSQTLPRAAAALGLFNEEGLESTGEDFLKKKYNVASYPTNDLKDLLP
                     GELPDMDFSHPKPTNQIQFNTFLAFVENFFKDLSDDNLKFLKMKYIIPDSLQFDKTYD
                     PEVNPFIIPKLGPLYTDVWFKDENDKNSAYKKPSPYSNDASTILPKKSANELDDNALE
                     SGSISCGPLLSRLLSAVLKDDNDKSELQSSKIIRDGGLPRTGGEDDIQSFRNNNNDTV
                     DMTLSQENGPSVQTPDNDIDEEASFQAKLAENKGSNGGTTSTLPQQIGWITNGINLDY
                     PTFEERLKRELKYVGIYMNLPKDENNPNSDDPDWVTGREDDEISAELRELQGTLKQVT
                     KKNQKRKAQLIPLVERQLAWQEYSSILEDLDKQIDQAYVKRIRVPKKRKKHHTAASNN
                     VNTGTTSQIAQQKAANSSLKSLLDKRQRWINKIGPLFDKPEIMKRIPNESVFKDMDQE
                     EDEDEADVFAQNTNKDVELN"
     gene            <816878..>817525
                     /gene="UBC1"
                     /locus_tag="YDR177W"
                     /db_xref="GeneID:851757"
     mRNA            <816878..>817525
                     /gene="UBC1"
                     /locus_tag="YDR177W"
                     /product="E2 ubiquitin-conjugating protein UBC1"
                     /transcript_id="NM_001180484.3"
                     /db_xref="GI:398365964"
                     /db_xref="GeneID:851757"
     CDS             816878..817525
                     /gene="UBC1"
                     /locus_tag="YDR177W"
                     /EC_number="6.3.2.19"
                     /note="Ubiquitin-conjugating enzyme; key E2 partner with
                     Ubc4p for the anaphase-promoting complex (APC); mediates
                     selective degradation of short-lived and abnormal
                     proteins; plays a role in vesicle biogenesis and
                     ER-associated protein degradation (ERAD); component of the
                     cellular stress response; protein abundance increases in
                     response to DNA replication stress key E2 partner with
                     Ubc4p for the anaphase-promoting complex (APC)"
                     /codon_start=1
                     /product="E2 ubiquitin-conjugating protein UBC1"
                     /protein_id="NP_010462.3"
                     /db_xref="GI:398365965"
                     /db_xref="SGD:S000002584"
                     /db_xref="GeneID:851757"
                     /translation="MSRAKRIMKEIQAVKDDPAAHITLEFVSESDIHHLKGTFLGPPG
                     TPYEGGKFVVDIEVPMEYPFKPPKMQFDTKVYHPNISSVTGAICLDILKNAWSPVITL
                     KSALISLQALLQSPEPNDPQDAEVAQHYLRDRESFNKTAALWTRLYASETSNGQKGNV
                     EESDLYGIDHDLIDEFESQGFEKDKIVEVLRRLGVKSLDPNDNNTANRIIEELLK"
     gene            <817950..>818495
                     /gene="SDH4"
                     /locus_tag="YDR178W"
                     /gene_synonym="ACN18"
                     /db_xref="GeneID:851758"
     mRNA            <817950..>818495
                     /gene="SDH4"
                     /locus_tag="YDR178W"
                     /gene_synonym="ACN18"
                     /product="succinate dehydrogenase membrane anchor subunit
                     SDH4"
                     /transcript_id="NM_001180485.1"
                     /db_xref="GI:296143528"
                     /db_xref="GeneID:851758"
     CDS             817950..818495
                     /gene="SDH4"
                     /locus_tag="YDR178W"
                     /gene_synonym="ACN18"
                     /note="Membrane anchor subunit of succinate dehydrogenase;
                     involved in coupling the oxidation of succinate to the
                     transfer of electrons to ubiquinone as part of the TCA
                     cycle and the mitochondrial respiratory chain; SDH4 has a
                     paralog, SHH4, that arose from the whole genome
                     duplication"
                     /codon_start=1
                     /product="succinate dehydrogenase membrane anchor subunit
                     SDH4"
                     /protein_id="NP_010463.1"
                     /db_xref="GI:6320383"
                     /db_xref="SGD:S000002585"
                     /db_xref="GeneID:851758"
                     /translation="MMLPRSMKFMTGRRIFHTATVRAFQSTAKKSLTIPFLPVLPQKP
                     GGVRGTPNDAYVPPPENKLEGSYHWYMEKIFALSVVPLATTAMLTTGPLSTAADSFFS
                     VMLLGYCYMEFNSCITDYISERVYGVWHKYAMYMLGLGSAVSLFGIYKLETENDGVVG
                     LVKSLWDSSEKDNSQKIEAKK"
     gene            complement(<818708..>819196)
                     /gene="CSN9"
                     /locus_tag="YDR179C"
                     /db_xref="GeneID:851759"
     mRNA            complement(<818708..>819196)
                     /gene="CSN9"
                     /locus_tag="YDR179C"
                     /product="Csn9p"
                     /transcript_id="NM_001180486.1"
                     /db_xref="GI:296143529"
                     /db_xref="GeneID:851759"
     CDS             complement(818708..819196)
                     /gene="CSN9"
                     /locus_tag="YDR179C"
                     /note="Subunit of the Cop9 signalosome; Cop9 signalosome
                     is required for deneddylation, or removal of the
                     ubiquitin-like protein Rub1p from Cdc53p (cullin);
                     involved in adaptation to pheromone signaling"
                     /codon_start=1
                     /product="Csn9p"
                     /protein_id="NP_010464.1"
                     /db_xref="GI:6320384"
                     /db_xref="SGD:S000002586"
                     /db_xref="GeneID:851759"
                     /translation="MVMREETIKSLEDPYKYHYKEEWLNTKDPDEQQLFEIFAFGNIK
                     DLPENIILTSLMRSKLEKLTLVTLSEIYNELSYELIKEECQIEDDGIIESHLIQLQNI
                     FKAEMDSVSKSMKFSRRFDCRDVYCHEKELTIIKNPRVTKEYLVQNLRSWETKLKQNI
                     LE"
     gene            <819433..>820824
                     /locus_tag="YDR179W-A"
                     /db_xref="GeneID:851760"
     mRNA            <819433..>820824
                     /locus_tag="YDR179W-A"
                     /product="hypothetical protein"
                     /transcript_id="NM_001180487.3"
                     /db_xref="GI:398365980"
                     /db_xref="GeneID:851760"
     CDS             819433..820824
                     /locus_tag="YDR179W-A"
                     /codon_start=1
                     /product="hypothetical protein"
                     /protein_id="NP_010465.4"
                     /db_xref="GI:398365981"
                     /db_xref="SGD:S000002587"
                     /db_xref="GeneID:851760"
                     /translation="MPTILYNTNSSLITKYRRPNASNQYKGFLSKKGHTRLNSKSSGD
                     IWEKDCSHTKNSGNDVSFESEFEKDSVEYLRDLCFSIYPNSLHQKIRSIEALPDLQVN
                     TFIALIFQNFVKSWYGIKIPTDDSKFLTELYNLVQDLITYLKSSKINYHALLLDYIPC
                     LLSSHLKALNDSSQNNDLVYEQYCKLTLYDSKRYPMLFTEIIQSKMSTKSLLQRSFLD
                     SFLNELVFGHIFNSIAEPYYLLEGLNKICIRIKLNSAGNTRNEVTHGKPKCDPWLFVS
                     NVKHKILQMTRLLAYSTSTEAANMNTAEIQETAFLQRYIFTFFTDDFFKLSMRKPFLF
                     SICRTLQHWISKLNALNRVMYRTFDNIVQTKITSPVTIGNLFSLLRHSLFPNDNMMGP
                     PRVLPVGDAFLEFREECISNLWDVCMTYKLDHILAIKRSDIADLIICISKNRDCNKLL
                     IYRIIDCVIAQLP"
     gene            <821295..>825776
                     /gene="SCC2"
                     /locus_tag="YDR180W"
                     /db_xref="GeneID:851761"
     mRNA            <821295..>825776
                     /gene="SCC2"
                     /locus_tag="YDR180W"
                     /product="Scc2p"
                     /transcript_id="NM_001180488.3"
                     /db_xref="GI:398365986"
                     /db_xref="GeneID:851761"
     CDS             821295..825776
                     /gene="SCC2"
                     /locus_tag="YDR180W"
                     /note="Subunit of cohesin loading factor (Scc2p-Scc4p); a
                     complex required for loading of cohesin complexes onto
                     chromosomes; involved in establishing sister chromatid
                     cohesion during DSB repair via histone H2AX;
                     evolutionarily-conserved adherin; relocalizes to the
                     cytosol in response to hypoxia"
                     /codon_start=1
                     /product="Scc2p"
                     /protein_id="NP_010466.3"
                     /db_xref="GI:398365987"
                     /db_xref="SGD:S000002588"
                     /db_xref="GeneID:851761"
                     /translation="MSYPGKDKNIPGRIIEALEDLPLSYLVPKDGLAALVNAPMRVSL
                     PFDKTIFTSADDGRDVNINVLGTANSTTSSIKNEAEKERLVFKRPSNFTSSANSVDYV
                     PTNFLEGLSPLAQSVLSTHKGLNDSINIEKKSEIVSRPEAKHKLESVTSNAGNLSFND
                     NSSNKKTKTSTGVTMTQANLAEQYLNDLKNILDIVGFDQNSAEIGNIEYWLQLPNKKF
                     VLTTNCLTKLQMTIKNITDNPQLSNSIEITWLLRLLDVMVCNIKFSKSSLKMGLDDSM
                     LRYIALLSTIVLFNIFLLGKNDSNLHRESYIMEPVNFLSDLIESLKILTIEYGSLKIE
                     FDTFQEALELLPKYIRNGPFLDDNVTAKLVYIFSDLLMNNDIEATTNIQFQSFWDNVK
                     RISSDILVSLFGSFDQQRGFIIEELLSHIEKLPTKRIQKKLRKVGNQNIYITDFTFTL
                     MSMLENINCYSFCNQMKDIAPENIDLLKNEYKKQEEFLFNIVEHINDTILERFFKNPS
                     ALRYVIDNFVQDLLLLISSPQWPVTEKILSSLLKRLLSVYSPSMQVSANIETICLQLI
                     GNIGSTIFDIKCSTRDHEDNNLIKMINYPETLPHFFKSFEECIAYNETIKCRRSATRF
                     LWNLRLGTILILEEYTKDAKEQIITVDNELKKILEQIKDGGLGPELENREADFSTIKL
                     DYFSILHAFELLNLYDPYLKLILSLLAKDKIKLRSTAIKCLSMLASKDKVILSNPMVK
                     ETIHRRLNDSSASVKDAILDLVSINSSYFEFYQQINNNYNDDSIMVRKHVLRINEKMY
                     DETNDIVTKVYVIARILMKIEDEEDNIIDMARLILLNRWILKVHEVLDQPEKLKEISS
                     SVLLVMSRVAIMNEKCSQLFDLFLNFYLLNKEAHSKEAYDKITHVLTILTDFLVQKIV
                     ELNSDDTNEKNSIVDKQNFLNLLAKFADSTVSFLTKDHITALYPYMVSDEKSDFHYYI
                     LQVFRCTFEKLANFKQKFLYDLETTLLSRLPKMNVREIDEAMPLIWSVATHRHDTARV
                     AKACSSCLSHLHPYINKANNEEAAIVVDGKLQRLIYLSTGFARFCFPKPSNDKIAFLQ
                     EGETLYEHITKCLLVLSKDKITHVIRRVAVKNLTKLCGNHPKLFNSRHVLHLLDKEFQ
                     SDQLDIKLVILESLYDLFLLEERKSVRNTGVNSTLSSNSILKKKLLKTNRVEFANDGV
                     CSALATRFLDNILQLCLLRDLKNSLVAIRLLKLILKFGYTNPSHSIPTVIALFASTSQ
                     YIRHVAYELLEDLFEKYETLVFSSLSRGVTKAIHYSIHTDEKYYYKHDHFLSLLEKLC
                     GTGKKNGPKFFKVLKRIMQSYLDDITDLTSTNSSVQKSIFVLCTNISNITFVSQYDLV
                     SLLKTIDLTTDRLKEVIMDEIGDNVSSLSVSEEKLSGIILIQLSLQDLGTYLLHLYGL
                     RDDVLLLDIVEESELKNKQLPAKKPDISKFSAQLENIEQYSSNGKLLTYFRKHVKDT"
     gene            complement(<825910..>827355)
                     /gene="SAS4"
                     /locus_tag="YDR181C"
                     /db_xref="GeneID:851762"
     mRNA            complement(<825910..>827355)
                     /gene="SAS4"
                     /locus_tag="YDR181C"
                     /product="Sas4p"
                     /transcript_id="NM_001180489.1"
                     /db_xref="GI:296143532"
                     /db_xref="GeneID:851762"
     CDS             complement(825910..827355)
                     /gene="SAS4"
                     /locus_tag="YDR181C"
                     /note="Subunit of the SAS complex (Sas2p, Sas4p, Sas5p);
                     acetylates free histones and nucleosomes and regulates
                     transcriptional silencing; required for the HAT activity
                     of Sas2p"
                     /codon_start=1
                     /product="Sas4p"
                     /protein_id="NP_010467.1"
                     /db_xref="GI:6320387"
                     /db_xref="SGD:S000002589"
                     /db_xref="GeneID:851762"
                     /translation="MGIFQSIEEANNTSERLLRSEIKNSHGEFEKFDFDTEEYEINPK
                     RKLRLVSRINPNAGHLRKSKSCFTVDEHVDETRCQKPVMKSPFMSNVDDEIKKKRETI
                     TKMTLEIEHHELSQNIRKPTDDLLPDSTYQPYHKKMLKQENRMIQSDIVNGENEADRL
                     SLISDRLGMLNWEVTLQKVTKINDPTDENEMETKRYQTKELIDSMLHKFESMKKKSRN
                     LARRPASSDSLLKLVSGKDWPKIYTRIDRTFIPDYASSSDEEEEKITVEEIRERRLKK
                     REQQCGGSIIVLLSDHQSQKGMTRFAIVAEPLRKPYLIKTSTKERNSWKNKVPTNPKK
                     FKKAPRISTQIAVKRRREVIPLTMEVEPEVIRDIRQDTQKSMKLNVKAEEISVTETVK
                     SKEMNALRNNAASISPTLSEKAPLGSISSCTASQISQRSSENVGAIINNINPNLAIVP
                     SCNEKTFVKTHNGMKTNSGINILPVRKKKKV"
     gene            <827582..>829057
                     /gene="CDC1"
                     /locus_tag="YDR182W"
                     /gene_synonym="DSC1; DSR1; ESP2"
                     /db_xref="GeneID:851763"
     mRNA            <827582..>829057
                     /gene="CDC1"
                     /locus_tag="YDR182W"
                     /gene_synonym="DSC1; DSR1; ESP2"
                     /product="putative lipid phosphatase CDC1"
                     /transcript_id="NM_001180490.1"
                     /db_xref="GI:296143533"
                     /db_xref="GeneID:851763"
     CDS             827582..829057
                     /gene="CDC1"
                     /locus_tag="YDR182W"
                     /gene_synonym="DSC1; DSR1; ESP2"
                     /EC_number="3.1.-.-"
                     /note="Putative lipid phosphatase of the endoplasmic
                     reticulum; shows Mn2+ dependence and may affect Ca2+
                     signaling; mutants display actin and general growth
                     defects and pleiotropic defects in cell cycle progression
                     and organelle distribution"
                     /codon_start=1
                     /product="putative lipid phosphatase CDC1"
                     /protein_id="NP_010468.1"
                     /db_xref="GI:6320388"
                     /db_xref="SGD:S000002590"
                     /db_xref="GeneID:851763"
                     /translation="MVYRNRSKSVLSTHSKKSDDKAHYKSRSKKKSKSRSKKRLRIYW
                     RYISIVWILWLGLISYYESVVVKRAMKKCQWSTWEDWPEGAESHRVGLFADPQIMDEY
                     SYPGRPQIVNYFTRVIVDHYHRRNWKYVQYYLDPDSNFFLGDLFDGGRNWDDKQWIKE
                     YTRFNQIFPKKPLRRTVMSLPGNHDIGFGDTVVESSLQRFSSYFGETSSSLDAGNHTF
                     VLLDTISLSDKTNPNVSRVPRQFLDNFAMGSHPLPRILLTHVPLWRDPEQQTCGQLRE
                     SKEPFPIQKGHQYQTVIENDISQEILTKIQPEILFSGDDHDHCQISHSYPFQGKTKNA
                     QEITVKSCAMNMGISRPAIQLLSLYNPSDLTMVNAGGEYASKTYQTELCYMPDPYKAI
                     RMYLWGLLFSAAFIAYMHFFPKSFNNRVATIMNRVFTRPDGNTSDLPLPTSISKSKSK
                     KSLTHSKYAVNDTRSIKQFLVNAIVLFVSVMPIFIYFYTVV"
     gene            <829151..>829354
                     /locus_tag="YDR182W-A"
                     /db_xref="GeneID:1466434"
     mRNA            <829151..>829354
                     /locus_tag="YDR182W-A"
                     /product="hypothetical protein"
                     /transcript_id="NM_001184545.3"
                     /db_xref="GI:398365992"
                     /db_xref="GeneID:1466434"
     CDS             829151..829354
                     /locus_tag="YDR182W-A"
                     /note="hypothetical protein; identified by fungal homology
                     and RT-PCR"
                     /codon_start=1
                     /product="hypothetical protein"
                     /protein_id="NP_878063.3"
                     /db_xref="GI:398365993"
                     /db_xref="SGD:S000028539"
                     /db_xref="GeneID:1466434"
                     /translation="MNKRYKLYRVWYYYAHQTVCITSTGFALCFVVQAKTAGLGVTPI
                     TSLYGDKKEHLGKLLVPLVLYQI"
     gene            <829585..>830277
                     /gene="PLP1"
                     /locus_tag="YDR183W"
                     /db_xref="GeneID:851764"
     mRNA            <829585..>830277
                     /gene="PLP1"
                     /locus_tag="YDR183W"
                     /product="Plp1p"
                     /transcript_id="NM_001180491.3"
                     /db_xref="GI:398366004"
                     /db_xref="GeneID:851764"
     CDS             829585..830277
                     /gene="PLP1"
                     /locus_tag="YDR183W"
                     /note="Protein that interacts with CCT (chaperonin
                     containing TCP-1) complex; has a role in actin and tubulin
                     folding; has weak similarity to phosducins, which are
                     G-protein regulators"
                     /codon_start=1
                     /product="Plp1p"
                     /protein_id="NP_010469.3"
                     /db_xref="GI:398366005"
                     /db_xref="SGD:S000002591"
                     /db_xref="GeneID:851764"
                     /translation="MEDKLDRYYTNVLSNAEKDKHTTVDSDDKSSGEENLDELLNELD
                     RELDEDHEFLSAYRSERLQQISDHLKQVKKNVEDDGYGRLQCIDNEADAIQICTKTTM
                     VVIHFELETFGKCQYMNEKLENLAKRYLTTRFIKVNVQTCPFLVNKLNIKVLPFVVGY
                     KNGLEKVRYVGFSKLGNDPNGFDIRRLEQSLAHSGVIEDTFEIRKHSSVNTERFASTN
                     HDRSESDSDLDI"
     gene            complement(<830629..>831513)
                     /gene="ATC1"
                     /locus_tag="YDR184C"
                     /gene_synonym="LIC4"
                     /db_xref="GeneID:851765"
     mRNA            complement(<830629..>831513)
                     /gene="ATC1"
                     /locus_tag="YDR184C"
                     /gene_synonym="LIC4"
                     /product="Atc1p"
                     /transcript_id="NM_001180492.1"
                     /db_xref="GI:296143536"
                     /db_xref="GeneID:851765"
     CDS             complement(830629..831513)
                     /gene="ATC1"
                     /locus_tag="YDR184C"
                     /gene_synonym="LIC4"
                     /note="Nuclear protein; possibly involved in regulation of
                     cation stress responses and/or in the establishment of
                     bipolar budding pattern; relative distribution to the
                     nucleus decreases upon DNA replication stress"
                     /codon_start=1
                     /product="Atc1p"
                     /protein_id="NP_010470.1"
                     /db_xref="GI:6320390"
                     /db_xref="SGD:S000002592"
                     /db_xref="GeneID:851765"
                     /translation="MNTNQSNPNTDLTDDANIEHTLHRLLTQANNHFDDTVKIDGQSL
                     DLGKDLEQVMMDNLDCTDIFDSDIASQKHLTLESLFNDEHNTDSSTLLEMQRSANDSL
                     VGIDLDRHKKGYTGKASLDKSTNQNNVHKPDKEQKNYKIDKPTIKKKKSLLKTTNEPM
                     LSPASLSPSSSLASSDANESHLKIESMITDITSKIDSARQDIVSATKPAKFTNEFTIS
                     QISEMKARIINTHKLLLNFNFIKEGYARSCIQLKKSMDSLKDSEIHRAHLLVENDDLK
                     QQILELTQKLNEKSSKES"
     gene            complement(<831934..>832473)
                     /gene="UPS3"
                     /locus_tag="YDR185C"
                     /gene_synonym="GEP2"
                     /db_xref="GeneID:851766"
     mRNA            complement(<831934..>832473)
                     /gene="UPS3"
                     /locus_tag="YDR185C"
                     /gene_synonym="GEP2"
                     /product="Ups3p"
                     /transcript_id="NM_001180493.1"
                     /db_xref="GI:296143537"
                     /db_xref="GeneID:851766"
     CDS             complement(831934..832473)
                     /gene="UPS3"
                     /locus_tag="YDR185C"
                     /gene_synonym="GEP2"
                     /note="Mitochondrial hypothetical protein; similar to
                     Ups1p and Ups2p which are involved in regulation of
                     mitochondrial cardiolipin and phosphatidylethanolamine
                     levels; null is viable but interacts synthetically with
                     ups1 and ups2 mutations; UPS3 has a paralog, UPS2, that
                     arose from the whole genome duplication"
                     /codon_start=1
                     /product="Ups3p"
                     /protein_id="NP_010471.1"
                     /db_xref="GI:6320391"
                     /db_xref="SGD:S000002593"
                     /db_xref="GeneID:851766"
                     /translation="MKSFQKSYEFDYPWEKVTTANWMKYPNKISTHVIAVDVLRRELK
                     EHGDVLLTERLITIRQNTPHWMSILVGNTNLAYVREVSTVDRRDRSLTMRSCNMTFPH
                     ILKCYETVRYVPHPKNPSNVTLFKQDAKFLSGVPTKTFSEKVENWGVKRFSDNAVKGK
                     VGFDSILAMFNDIWKNANE"
     gene            complement(<832859..>835492)
                     /locus_tag="YDR186C"
                     /db_xref="GeneID:851767"
     mRNA            complement(<832859..>835492)
                     /locus_tag="YDR186C"
                     /product="hypothetical protein"
                     /transcript_id="NM_001180494.3"
                     /db_xref="GI:398366012"
                     /db_xref="GeneID:851767"
     CDS             complement(832859..835492)
                     /locus_tag="YDR186C"
                     /note="hypothetical protein; may interact with ribosomes,
                     based on co-purification experiments; green fluorescent
                     protein (GFP)-fusion protein localizes to the cytoplasm"
                     /codon_start=1
                     /product="hypothetical protein"
                     /protein_id="NP_010472.3"
                     /db_xref="GI:398366013"
                     /db_xref="SGD:S000002594"
                     /db_xref="GeneID:851767"
                     /translation="MDTVGTDAAAASINERRFAQSTSPKVSVKSQDSLFLITYSNMQQ
                     TVVQASLADRYPSLKKLNILLYIDIPTIDYYNDEMTHNKLSRLNKRFKLHRLRNSIAQ
                     SFSNTSTAEDNDKFWEELKSLISSRSTPENKFDLNVLVSSSGSLRYVETIRFLVEKLF
                     NSFKDLYVQKKLNLCFQINVSPTSLKWFSTFLNAELLNLKIINWQNIGSFTKTIQNSK
                     SLPFKEYYTKLNEKFTGSNQSNGSMQDQTVLDSIVIVTNSTGVKALLTLLSDHPLTSL
                     ISQESIKALHEYSDAVNEDKGDDQSNTSLKRNSSSLLNFQNSVLTSNKDKSVRIRSLS
                     INRKSNRAHMFKTNESITTIPSTSINNLIGQESNLRKQPSGTALHLQSHLHPHSRSQS
                     YSSSNMSRSPSPFPYGKTPSNDELVYDELNNQINEVQDRAKNEEIVLYNNNNYDDYTK
                     ERGEQEQDRTSYADEYGFNYDDEEGGNEDNYDDDEDDDDDDDDDDESDDEGLSFYAPS
                     ILSRSGSSTDVLSSGIDSMAKNSKETRGRFRSLSLMDPALQKPFNQKFPNSQQPDSAG
                     ASSPKRSTSSNHFTNVYVHDGDFDGTDTINNKKNLSSATLIKRKSLMNRNLAPSISNG
                     LIPPEFISRISTPSTSASSSNSSLNDMSTVSNAFSKLLNDTSKKQKFLNSPIPQHTQQ
                     ASPLLMRNNSNSNLLFEKNLINKSFEELRRQPSVNLFSTLMNGNMEKNGLALNFKSRT
                     PTDALMANSIKNSNNSSHRLLNLEEEDQIMSGSLPKEREDDNDSTNSTIVPNHPDNDN
                     YNDNDNDNNTGINSNNFNLNLYDDNDSAGFTDVTTEGVKYSNSNSTVTKPVYKKAVTL
                     DLYGEDDMDNMGGWVLGGNAR"
     gene            <836421..>838061
                     /gene="CCT6"
                     /locus_tag="YDR188W"
                     /gene_synonym="HTR3; TCP20; TCP6"
                     /db_xref="GeneID:851768"
     mRNA            <836421..>838061
                     /gene="CCT6"
                     /locus_tag="YDR188W"
                     /gene_synonym="HTR3; TCP20; TCP6"
                     /product="Cct6p"
                     /transcript_id="NM_001180496.3"
                     /db_xref="GI:398366020"
                     /db_xref="GeneID:851768"
     CDS             836421..838061
                     /gene="CCT6"
                     /locus_tag="YDR188W"
                     /gene_synonym="HTR3; TCP20; TCP6"
                     /note="Subunit of the cytosolic chaperonin Cct ring
                     complex; related to Tcp1p, essential protein that is
                     required for the assembly of actin and tubulins in vivo;
                     contains an ATP-binding motif"
                     /codon_start=1
                     /product="Cct6p"
                     /protein_id="NP_010474.3"
                     /db_xref="GI:398366021"
                     /db_xref="SGD:S000002596"
                     /db_xref="GeneID:851768"
                     /translation="MSLQLLNPKAESLRRDAALKVNVTSAEGLQSVLETNLGPKGTLK
                     MLVDGAGNIKLTKDGKVLLTEMQIQSPTAVLIARAAAAQDEITGDGTTTVVCLVGELL
                     RQAHRFIQEGVHPRIITDGFEIARKESMKFLDEFKISKTNLSNDREFLLQVARSSLLT
                     KVDADLTEVLTPIVTDAVLSVYDAQADNLDLHMVEIMQMQHLSPKDTTFIKGLVLDHG
                     GRHPDMPTRVKNAYVLILNVSLEYEKTEVNSGFFYSSADQRDKLAASERKFVDAKLKK
                     IIDLKNEVCGMDPDKGFVIINQKGIDPMSLDVFAKHNILALRRAKRRNMERLQLVTGG
                     EAQNSVEDLSPQILGFSGLVYQETIGEEKFTYVTENTDPKSCTILIKGSTHYALAQTK
                     DAVRDGLRAVANVLKDKNIIPGAGAFYIALSRYLRSANMNKLGAKGKTKTGIEAFAEA
                     LLVIPKTLVKNSGFDPLDVLAMVEDELDDAQDSDETRYVGVDLNIGDSCDPTIEGIWD
                     SYRVLRNAITGATGIASNLLLCDELLRAGRSTLKETPQ"
     gene            <838392..>840392
                     /gene="SLY1"
                     /locus_tag="YDR189W"
                     /db_xref="GeneID:851770"
     mRNA            <838392..>840392
                     /gene="SLY1"
                     /locus_tag="YDR189W"
                     /product="Sly1p"
                     /transcript_id="NM_001180497.1"
                     /db_xref="GI:296143540"
                     /db_xref="GeneID:851770"
     CDS             838392..840392
                     /gene="SLY1"
                     /locus_tag="YDR189W"
                     /note="Hydrophilic protein involved in ER/Golgi vesicle
                     trafficking; SM (Sec1/Munc-18) family protein that binds
                     the tSNARE Sed5p and stimulates its assembly into a
                     trans-SNARE membrane-protein complex"
                     /codon_start=1
                     /product="Sly1p"
                     /protein_id="NP_010475.1"
                     /db_xref="GI:6320395"
                     /db_xref="SGD:S000002597"
                     /db_xref="GeneID:851770"
                     /translation="MAVEEIASRKDISLRDMQISAILKMLFLNKDLNNNDNITTITDD
                     IFNQQEIIWKVLILDIKSTATISSVLRVNDLLKAGITVHSLIKQDRSPLPDVPAIYFV
                     SPTKENIDIIVNDLKSDKYSEFYINFTSSLPRNLLEDLAQQVSITGKSDKIKQVYDQY
                     LDFIVTEPELFSLEISNAYLTLNDPKTTEEEITGLCANIADGLFNTVLTINSIPIIRA
                     AKGGPAEIIAEKLGTKLRDFVINTNSSSTSTLQGNDSLERGVLIILDRNIDFASMFSH
                     SWIYQCMVFDIFKLSRNTVTIPLESKENGTDNTTAKPLATKKYDIEPNDFFWMENSHL
                     PFPEAAENVEAALNTYKEEAAEITRKTGVTNISDLDPNSNNDTVQIQEVVKKLPELTA
                     KKNTIDTHMNIFAALLSQLESKSLDTFFEVEQDPGSTKTRSRFLDILKDGKTNNLEDK
                     LRSFIVLYLTSTTGLPKDFVQNVENYFKENDYDINALKYVYKLREFMQLSNMSLQNKS
                     LEDGSDSAFKPSNLTLSGIYGLTEGKLQGGVGSLISGIKKLLPEKKTIPITNVVDAIM
                     DPLNSSQKNLETTDSYLYIDPKITRGSHTRKPKRQSYNKSLVFVVGGGNYLEYQNLQE
                     WAHSQLHNPKKVMYGSTAITTPAEFLNEISRLGASNSSNNDA"
     gene            complement(<840604..>841995)
                     /gene="RVB1"
                     /locus_tag="YDR190C"
                     /gene_synonym="TIH1; TIP49; TIP49A"
                     /db_xref="GeneID:851771"
     mRNA            complement(<840604..>841995)
                     /gene="RVB1"
                     /locus_tag="YDR190C"
                     /gene_synonym="TIH1; TIP49; TIP49A"
                     /product="RuvB family ATP-dependent DNA helicase pontin"
                     /transcript_id="NM_001180498.1"
                     /db_xref="GI:296143541"
                     /db_xref="GeneID:851771"
     CDS             complement(840604..841995)
                     /gene="RVB1"
                     /locus_tag="YDR190C"
                     /gene_synonym="TIH1; TIP49; TIP49A"
                     /EC_number="3.6.4.12"
                     /note="ATP-dependent DNA helicase, also known as pontin;
                     member of the AAA+ and RuvB-like protein families; similar
                     to Rvb2p; conserved component of multiple complexes
                     including the INO80 complex, the Swr1 complex, and the
                     R2TP complex (Rvb1-Rvb2-Tah1-Pih1); involved in multiple
                     processes such as chromatin remodeling, box C/D snoRNP
                     assembly, and RNA polymerase II assembly"
                     /codon_start=1
                     /product="RuvB family ATP-dependent DNA helicase pontin"
                     /protein_id="NP_010476.1"
                     /db_xref="GI:6320396"
                     /db_xref="SGD:S000002598"
                     /db_xref="GeneID:851771"
                     /translation="MVAISEVKENPGVNSSNSGAVTRTAAHTHIKGLGLDESGVAKRV
                     EGGFVGQIEAREACGVIVDLIKAKKMSGRAILLAGGPSTGKTALALAISQELGPKVPF
                     CPLVGSELYSVEVKKTETLMENFRRAIGLRIKETKEVYEGEVTELTPEDAENPLGGYG
                     KTISHVIVGLKSAKGTKTLRLDPTIYESIQREKVSIGDVIYIEANTGAVKRVGRSDAY
                     ATEFDLETEEYVPLPKGEVHKKKEIVQDVTLHDLDVANARPQGGQDVISMMGQLLKPK
                     KTEITEKLRQEVNKVVAKYIDQGVAELIPGVLFIDEVNMLDIEIFTYLNKALESNIAP
                     VVVLASNRGMTTVRGTEDVISPHGVPPDLIDRLLIVRTLPYDKDEIRTIIERRATVER
                     LQVESSALDLLATMGTETSLRYALQLLAPCGILAQTSNRKEIVVNDVNEAKLLFLDAK
                     RSTKILETSANYL"
     gene            <842337..>843449
                     /gene="HST4"
                     /locus_tag="YDR191W"
                     /db_xref="GeneID:851772"
     mRNA            <842337..>843449
                     /gene="HST4"
                     /locus_tag="YDR191W"
                     /product="Hst4p"
                     /transcript_id="NM_001180499.3"
                     /db_xref="GI:398366028"
                     /db_xref="GeneID:851772"
     CDS             842337..843449
                     /gene="HST4"
                     /locus_tag="YDR191W"
                     /EC_number="3.5.1.-"
                     /note="Member of the Sir2 family of NAD(+)-dependent
                     protein deacetylases; involved along with Hst3p in
                     silencing at telomeres, cell cycle progression, radiation
                     resistance, genomic stability and short-chain fatty acid
                     metabolism"
                     /codon_start=1
                     /product="Hst4p"
                     /protein_id="NP_010477.3"
                     /db_xref="GI:398366029"
                     /db_xref="SGD:S000002599"
                     /db_xref="GeneID:851772"
                     /translation="MKQKFVLPITPPSTAEKKPQTENRCNENLKPRRLLPQLKKSVRN
                     RKPRLSYRPELNSVFDLDAYVDSTHLSKSQRHHMDRDAGFISYALNYSKRMVVVSGAG
                     ISVAAGIPDFRSSEGIFSTVNGGSGKDLFDYNRVYGDESMSLKFNQLMVSLFRLSKNC
                     QPTKFHEMLNEFARDGRLLRLYTQNIDGLDTQLPHLSTNVPLAKPIPSTVQLHGSIKH
                     MECNKCLNIKPFDPELFKCDDKFDSRTEIIPSCPQCEEYETVRKMAGLRSTGVGKLRP
                     RVILYNEVHPEGDFIGEIANNDLKKRIDCLIIVGTSLKIPGVKNICRQFAAKVHANRG
                     IVLYLNTSMPPKNVLDSLKFVDLVVLGDCQHVTSLL"
     gene            complement(<843569..>844861)
                     /gene="NUP42"
                     /locus_tag="YDR192C"
                     /gene_synonym="RIP1; UIP1"
                     /db_xref="GeneID:851774"
     mRNA            complement(<843569..>844861)
                     /gene="NUP42"
                     /locus_tag="YDR192C"
                     /gene_synonym="RIP1; UIP1"
                     /product="Nup42p"
                     /transcript_id="NM_001180500.3"
                     /db_xref="GI:398366036"
                     /db_xref="GeneID:851774"
     CDS             complement(843569..844861)
                     /gene="NUP42"
                     /locus_tag="YDR192C"
                     /gene_synonym="RIP1; UIP1"
                     /note="FG-nucleoporin component of central core of the
                     nuclear pore complex; also part of the nuclear pore
                     complex (NPC) cytoplasmic filaments; contributes directly
                     to nucleocytoplasmic transport and maintenance of the NPC
                     permeability barrier and is involved in gene tethering at
                     the nuclear periphery; interacts with Gle1p"
                     /codon_start=1
                     /product="Nup42p"
                     /protein_id="NP_010478.3"
                     /db_xref="GI:398366037"
                     /db_xref="SGD:S000002600"
                     /db_xref="GeneID:851774"
                     /translation="MSAFGNPFTSGAKPNLSNTSGINPFTNNAASTNNMGGSAFGRPS
                     FGTANTMTGGTTTSAFGMPQFGTNTGNTGNTSISAFGNTSNAAKPSAFGAPAFGSSAP
                     INVNPPSTTSAFGAPSFGSTGFGAMAATSNPFGKSPGSMGSAFGQPAFGANKTAIPSS
                     SVSNSNNSAFGAASNTPLTTTSPFGSLQQNASQNASSTSSAFGKPTFGAATNTQSPFG
                     TIQNTSTSSGTGVSPFGTFGTNSNNKSPFSNLQSGAGAGSSPFGTTTSKANNNNNVGS
                     SAFGTTNNQSPFSGGSGGTFGSASNLNKNTNGNFQSSFGNKGFSFGITPQNDANKVSQ
                     SNPSFGQTMPNTDPNISLKSNGNATSFGFGQQQMNATNVNANTATGKIRFVQGLSSEK
                     DGILELADLAEETLKIFRANKFELGLVPDIPPPPALVA"
     gene            complement(<845952..>847946)
                     /gene="MSS116"
                     /locus_tag="YDR194C"
                     /db_xref="GeneID:851775"
     mRNA            complement(<845952..>847946)
                     /gene="MSS116"
                     /locus_tag="YDR194C"
                     /product="Mss116p"
                     /transcript_id="NM_001180502.1"
                     /db_xref="GI:296143544"
                     /db_xref="GeneID:851775"
     CDS             complement(845952..847946)
                     /gene="MSS116"
                     /locus_tag="YDR194C"
                     /EC_number="3.6.4.13"
                     /note="Mitochondrial transcription elongation factor;
                     DEAD-box protein; required for efficient splicing of
                     mitochondrial Group I and II introns; non-polar RNA
                     helicase that also facilities strand annealing; promotes
                     RNA folding by stabilizing an early assembly intermediate"
                     /codon_start=1
                     /product="Mss116p"
                     /protein_id="NP_010480.1"
                     /db_xref="GI:6320400"
                     /db_xref="SGD:S000002602"
                     /db_xref="GeneID:851775"
                     /translation="MLTSILIKGRTPVLASRNLLAALSNCNHITWAVSRRLYNDGNRD
                     QRNFGRNQRNNNSNRYRNSRFNSRPRTRSREDDDEVHFDKTTFSKLIHVPKEDNSKEV
                     TLDSLLEEGVLDKEIHKAITRMEFPGLTPVQQKTIKPILSSEDHDVIARAKTGTGKTF
                     AFLIPIFQHLINTKFDSQYMVKAVIVAPTRDLALQIEAEVKKIHDMNYGLKKYACVSL
                     VGGTDFRAAMNKMNKLRPNIVIATPGRLIDVLEKYSNKFFRFVDYKVLDEADRLLEIG
                     FRDDLETISGILNEKNSKSADNIKTLLFSATLDDKVQKLANNIMNKKECLFLDTVDKN
                     EPEAHERIDQSVVISEKFANSIFAAVEHIKKQIKERDSNYKAIIFAPTVKFTSFLCSI
                     LKNEFKKDLPILEFHGKITQNKRTSLVKRFKKDESGILVCTDVGARGMDFPNVHEVLQ
                     IGVPSELANYIHRIGRTARSGKEGSSVLFICKDELPFVRELEDAKNIVIAKQEKYEPS
                     EEIKSEVLEAVTEEPEDISDIVISLISSYRSCIKEYRFSERRILPEIASTYGVLLNDP
                     QLKIPVSRRFLDKLGLSRSPIGKAMFEIRDYSSRDGNNKSYDYDDDSEISFRGNKNYN
                     NRSQNRDYDDEPFRRSNNNRRSFSRSNDKNNYSSRNSNIY"
     gene            <848071..>848223
                     /locus_tag="YDR194W-A"
                     /db_xref="GeneID:1466435"
     mRNA            <848071..>848223
                     /locus_tag="YDR194W-A"
                     /product="hypothetical protein"
                     /transcript_id="NM_001184546.1"
                     /db_xref="GI:296143545"
                     /db_xref="GeneID:1466435"
     CDS             848071..848223
                     /locus_tag="YDR194W-A"
                     /note="hypothetical protein; identified by fungal homology
                     and RT-PCR"
                     /codon_start=1
                     /product="hypothetical protein"
                     /protein_id="NP_878064.1"
                     /db_xref="GI:33438782"
                     /db_xref="SGD:S000028541"
                     /db_xref="GeneID:1466435"
                     /translation="MKQMMIEASISKDTLRLLICFFEIKQCHISLQPTCYYQNWVRYS
                     SIYYQL"
     gene            <848599..>850200
                     /gene="REF2"
                     /locus_tag="YDR195W"
                     /db_xref="GeneID:851776"
     mRNA            <848599..>850200
                     /gene="REF2"
                     /locus_tag="YDR195W"
                     /product="Ref2p"
                     /transcript_id="NM_001180503.3"
                     /db_xref="GI:398366050"
                     /db_xref="GeneID:851776"
     CDS             848599..850200
                     /gene="REF2"
                     /locus_tag="YDR195W"
                     /note="RNA-binding protein; involved in the cleavage step
                     of mRNA 3'-end formation prior to polyadenylation, and in
                     snoRNA maturation; part of holo-CPF subcomplex APT, which
                     associates with 3'-ends of snoRNA- and mRNA-encoding
                     genes; relocalizes to the cytosol in response to hypoxia"
                     /codon_start=1
                     /product="Ref2p"
                     /protein_id="NP_010481.3"
                     /db_xref="GI:398366051"
                     /db_xref="SGD:S000002603"
                     /db_xref="GeneID:851776"
                     /translation="MSAPVPQLVNISHALQASTIQQIRLDMVDFNKDCKLSSIQLARI
                     DKYIDSLQAALNQFTKDNLHIERKEKNVTEADIQLYSGLKSMYLDYLNQLIKLKHEKQ
                     HHSTPPIANDVSLDFFVNQLPKFSPEERKNYIDNLILNKNSHNRLSKMDGLVDAVINL
                     CVLDTSVAENVRSYMKLLDTLGFQKGSNSTGTKANLKKKLASSKAKIKDSEKEKEKEK
                     DKSKVKMKTKLKPSPLLNNDDKNSSPSPTASTSSMKKLKSGLFNKNEAKSTESLPTSS
                     KKKLSFSKYLNKDDADMTKLGTKRSIDVDFKVNPEASTVASNIISSSTSGSSTTTVAT
                     PASSEEPLKKKTKISVQDSNVQSILRNGKPKKARISSIKFLDDSQLIKVYGDDLPNQG
                     LQVSPTQLKKILKPFKEGEPKEIILFEDMSIKLKPLDLMFLKNTNSDDYMDISETKGG
                     PIHCETRTPLIYRKNFNHFNPDLNKRPPREPIEFDLNGNTNSTPTIAKAFGKNSLLLR
                     KDRGGLPYKHVPIVKRNKYPPRPVH"
     gene            complement(<850274..>850999)
                     /gene="CAB5"
                     /locus_tag="YDR196C"
                     /db_xref="GeneID:851777"
     mRNA            complement(<850274..>850999)
                     /gene="CAB5"
                     /locus_tag="YDR196C"
                     /product="putative dephospho-CoA kinase"
                     /transcript_id="NM_001180504.3"
                     /db_xref="GI:398366056"
                     /db_xref="GeneID:851777"
     CDS             complement(850274..850999)
                     /gene="CAB5"
                     /locus_tag="YDR196C"
                     /EC_number="2.7.1.24"
                     /note="Subunit of the CoA-Synthesizing Protein Complex
                     (CoA-SPC); subunits of this complex are: Cab2p, Cab3p,
                     Cab4p, Cab5p, Sis2p and Vhs3p; probable dephospho-CoA
                     kinase (DPCK) that catalyzes the last step in coenzyme A
                     biosynthesis; null mutant lethality is complemented by E.
                     coli coaE (encoding DPCK); detected in purified
                     mitochondria in high-throughput studies; also localized to
                     lipid droplets"
                     /codon_start=1
                     /product="putative dephospho-CoA kinase"
                     /protein_id="NP_010482.3"
                     /db_xref="GI:398366057"
                     /db_xref="SGD:S000002604"
                     /db_xref="GeneID:851777"
                     /translation="MLVVGLTGGIACGKSTVSRRLRDKYKLPIVDADKIARQVVEPGQ
                     NAYDQIVLYFKDKIPNLLLEDGHLNREALGKWVFSHKEDLQALNGITHPAIRYAMFKE
                     IGYYYLKGYRMCVLDVPLLFEGNLDSICGVTVSVICTQELQLERLMTRNPELSEEDAK
                     NRLNSQMSTEERMARSDYILQNNSTLVDLYEQIESVVKKIQPSKLRTVLEYFPPFGAV
                     SASSIVMSRLLMKKLQNKKSSAV"
     gene            <851228..>852397
                     /gene="CBS2"
                     /locus_tag="YDR197W"
                     /gene_synonym="CBP7"
                     /db_xref="GeneID:851778"
     mRNA            <851228..>852397
                     /gene="CBS2"
                     /locus_tag="YDR197W"
                     /gene_synonym="CBP7"
                     /product="Cbs2p"
                     /transcript_id="NM_001180505.1"
                     /db_xref="GI:296143548"
                     /db_xref="GeneID:851778"
     CDS             851228..852397
                     /gene="CBS2"
                     /locus_tag="YDR197W"
                     /gene_synonym="CBP7"
                     /note="Mitochondrial translational activator of the COB
                     mRNA; interacts with translating ribosomes, acts on the
                     COB mRNA 5'-untranslated leader"
                     /codon_start=1
                     /product="Cbs2p"
                     /protein_id="NP_010483.1"
                     /db_xref="GI:6320403"
                     /db_xref="SGD:S000002605"
                     /db_xref="GeneID:851778"
                     /translation="MSSSIPRVYSLGNSAMTYLLALRIAQLPSQPKVPSVVLLLNDQK
                     KLNRFLNNDSKIIVKSSNNNKETYHRQFMASCVPPILSNGEIAPIENLIVSDPSSKFI
                     TAQLSKYNKSLRPETNILFLNPSLNLLEHLHRYRWRFDEARPNLFMGFTTPVDVGTIH
                     QEFQLSLKVKGRIQFHIAKIDGFPRMSSTGKSASLSLRGDRQKNEKENNAFYKLFREI
                     SRLRSGIGSDLVSFDLHVHGFQDLFFTELEKLILESCTEPLLAVYDCVYKKELLKIPG
                     AQDIIKKLISEQLSIIDRSYPSLNTNPNYSVIFDKERIFSLVMRDLEVNGHKRAKLAQ
                     SLNQLNQTNINELNGFFVSLGKYKKCNCKWNDILLTLIKGKQFITKQKALDYHYL"
     gene            complement(<852533..>853972)
                     /gene="RKM2"
                     /locus_tag="YDR198C"
                     /db_xref="GeneID:851779"
     mRNA            complement(<852533..>853972)
                     /gene="RKM2"
                     /locus_tag="YDR198C"
                     /product="Rkm2p"
                     /transcript_id="NM_001180506.1"
                     /db_xref="GI:296143549"
                     /db_xref="GeneID:851779"
     CDS             complement(852533..853972)
                     /gene="RKM2"
                     /locus_tag="YDR198C"
                     /EC_number="2.1.1.-"
                     /note="Ribosomal protein lysine methyltransferase;
                     responsible for trimethylation of the lysine residue at
                     position 3 of Rpl12Ap and Rpl12Bp"
                     /codon_start=1
                     /product="Rkm2p"
                     /protein_id="NP_010484.1"
                     /db_xref="GI:6320404"
                     /db_xref="SGD:S000002606"
                     /db_xref="GeneID:851779"
                     /translation="MEGKVDVLLTWLKKSDKFYIAPNISICESPETGRGIVLSHGSIR
                     KNDIIVSVPSSKQLNFHTILYHISKFNKELNIPGITIDRKPINYEDNIIEAENKAWAD
                     PRYGLYSELSKEFLLSLSSFQLVSFYILVENFLLPKWTHNEIYSDWKPFFDVWPSMEE
                     LRSIPAIWNCDPNSRYHSLIEYLPAASRKHMARISGLVREDWETISEVVLKWNEIYGS
                     LSCTKNSDKFTSDELFSLFVHVYFIINSRCLYAKIPLKIEDSPSNFTLVPYVDFMNHI
                     CESDLHCYPQLSPQLRSEGENIIGIGQFTIRCGDHLYDNINEELFLNYGAHSNDFLLN
                     EYGFVVDGNKWNYLDISDEIIELIDDDKKEVKTFLLEHDYWGDYTINETDISYRIFVA
                     LNYYVTRDERRVRKFIEGYISEDYFKPKISSVLKELLVSLTAKYTKTLSELTEKVSNL
                     ENNLCLQNLITIYKGYIKILTQHLQDLQS"
     gene            complement(<854279..>856093)
                     /gene="VPS64"
                     /locus_tag="YDR200C"
                     /gene_synonym="FAR9"
                     /db_xref="GeneID:851781"
     mRNA            complement(<854279..>856093)
                     /gene="VPS64"
                     /locus_tag="YDR200C"
                     /gene_synonym="FAR9"
                     /product="Vps64p"
                     /transcript_id="NM_001180508.3"
                     /db_xref="GI:398366070"
                     /db_xref="GeneID:851781"
     CDS             complement(854279..856093)
                     /gene="VPS64"
                     /locus_tag="YDR200C"
                     /gene_synonym="FAR9"
                     /note="Protein required for cytoplasm to vacuole targeting
                     of proteins; forms a complex with Far3p and Far7p to
                     Far11p involved in recovery from pheromone-induced cell
                     cycle arrest; mutant has increased aneuploidy tolerance;
                     VPS64 has a paralog, FAR10, that arose from the whole
                     genome duplication"
                     /codon_start=1
                     /product="Vps64p"
                     /protein_id="NP_010486.3"
                     /db_xref="GI:398366071"
                     /db_xref="SGD:S000002608"
                     /db_xref="GeneID:851781"
                     /translation="MVELEKRRRPPPQLQHSPYVRDQSNSQGMTKTPETSPPKRPMGR
                     ARSNSRSSGSRSNVDIDQYTIPPGLDLLPTASSPPSVHQVSQQQQLSPILANKIRSPF
                     ENQSQDQNDNSIDPTPAGQVTIPVEAVSPPALDELSKFQNGSTETLFRTGSPRKKHTH
                     IIILKSLNATFETKFLVVPFKPDGLKLGRPVTNSVNKNNSGSKRDLFSQQVRPDNGNF
                     DSRVLSRNHACLSCDPTSGKIYIRDLKSSNGTFVNGVKIRQNDVELKVGDTVDLGTDI
                     DSKFEHRKISAYVEEISVIPLMNTVSDPTNLVMKKQDHTNKNNGNSTNINGIKIDRGH
                     HNQHIPIRSHLKENYTEAGVTSATTAQRAAFEAAMFGDINNSELDDDILGPETEVLSG
                     IFINNSAGTSINLINMIKTLTTELSLEKQELEKLHSMQNFMQNYTINLDFINKHMIDM
                     NEKHLLKLSTALQKTLSENNDALLKESEDQLKEIKQQNNKVKSACSLKEKQNHEKLQE
                     LESELRELNLQIEEERGKNLVLTQSNFNGGINNDNNAKVKQNDSREEKKDTEDTLIST
                     EELGVVEGKRTRVSKGMLFGVVAISFGLVATAVKQLPQ"
     gene            <856317..>856814
                     /gene="SPC19"
                     /locus_tag="YDR201W"
                     /db_xref="GeneID:851782"
     mRNA            <856317..>856814
                     /gene="SPC19"
                     /locus_tag="YDR201W"
                     /product="Spc19p"
                     /transcript_id="NM_001180509.3"
                     /db_xref="GI:398366076"
                     /db_xref="GeneID:851782"
     CDS             856317..856814
                     /gene="SPC19"
                     /locus_tag="YDR201W"
                     /note="Essential subunit of the Dam1 complex (aka DASH
                     complex); complex couples kinetochores to the force
                     produced by MT depolymerization thereby aiding in
                     chromosome segregation; also localized to nuclear side of
                     spindle pole body"
                     /codon_start=1
                     /product="Spc19p"
                     /protein_id="NP_010487.3"
                     /db_xref="GI:398366077"
                     /db_xref="SGD:S000002609"
                     /db_xref="GeneID:851782"
                     /translation="MTDALEQSVLALEGTVSVLKDSVESLKCANEPSTNLASTMLQTK
                     RVFRLVPEYDVERSKLDLIEEVEPLVRTLGDKLRKSMGRMQRELDTLQQTYELNDLRL
                     KKNISMDDDDALNSPDMGQEYEGRDADDVVMMASSTNEELEELKKLKEKKKQLENKLE
                     ILKQK"
     gene            complement(<856898..>857953)
                     /gene="RAV2"
                     /locus_tag="YDR202C"
                     /db_xref="GeneID:851784"
     mRNA            complement(<856898..>857953)
                     /gene="RAV2"
                     /locus_tag="YDR202C"
                     /product="Rav2p"
                     /transcript_id="NM_001180510.1"
                     /db_xref="GI:296143552"
                     /db_xref="GeneID:851784"
     CDS             complement(856898..857953)
                     /gene="RAV2"
                     /locus_tag="YDR202C"
                     /note="Subunit of RAVE complex (Rav1p, Rav2p, Skp1p); the
                     RAVE complex associates with the V1 domain of the vacuolar
                     membrane (H+)-ATPase (V-ATPase) and promotes assembly and
                     reassembly of the holoenzyme"
                     /codon_start=1
                     /product="Rav2p"
                     /protein_id="NP_010488.1"
                     /db_xref="GI:6320409"
                     /db_xref="SGD:S000002610"
                     /db_xref="GeneID:851784"
                     /translation="MSVDLFPNDRFGAEDKYDNFKDAVKECSWLIEEIVKPQLPNIID
                     NFSKCLEMLESDQIFKMPVSNGIPNESNKQNDSPTVKGVITRQGQYIVDFHIVVRFPQ
                     FQRGKQVMFRMNTGLNFLLIQFSKIMTHLKNILEILNQLQVATDVSEFVSKFGVAMEL
                     LNHSLILLQNPPRDLVFPEDNNFAMKEMFQDCYSVCESTAHILGLELTLCRNELCIEL
                     RNLIKVTKKPWCEIDSKTGRSFCDQIRNQVTNERNKTLSKILSENGVQVQDSTLLNHI
                     ISSFQSEAITLPEAQELLRRGVTFDNRVVMECEKLIVSTSDPTLISISAKLNSLKASM
                     ANHQANLVASKQLSTYK"
     gene            <858137..>859144
                     /gene="COQ4"
                     /locus_tag="YDR204W"
                     /db_xref="GeneID:851785"
     mRNA            <858137..>859144
                     /gene="COQ4"
                     /locus_tag="YDR204W"
                     /product="Coq4p"
                     /transcript_id="NM_001180512.1"
                     /db_xref="GI:296143553"
                     /db_xref="GeneID:851785"
     CDS             858137..859144
                     /gene="COQ4"
                     /locus_tag="YDR204W"
                     /note="Protein with a role in ubiquinone (Coenzyme Q)
                     biosynthesis; possibly functioning in stabilization of
                     Coq7p; located on the matrix face of the mitochondrial
                     inner membrane; component of a mitochondrial
                     ubiquinone-synthesizing complex"
                     /codon_start=1
                     /product="Coq4p"
                     /protein_id="NP_010490.1"
                     /db_xref="GI:6320410"
                     /db_xref="SGD:S000002612"
                     /db_xref="GeneID:851785"
                     /translation="MLRLSLLRSTATLPVKCQRRGLILPAAAMYTLGSLIFGKEARLA
                     DAMERGELHNKNVDYAKEAEERTELRIRALANTRPMEPRYNGHVPLHRYEKLLLFAIS
                     GWNSFFHPEDGYNIVQLGEATALPVFLENLKQTMLSDSSGRRILKEQPNITTEILHMD
                     KLAKLPHNTFGYVYYQWLKRENVSPDTRAPVKFIDDPMHAYIFKRYRQCHDFYHAITN
                     MPIIIEGEITIKALEGANLGVPMAILGGILAPLRLKKVQRKRLYNIYLPWAVRTGLSC
                     KPLINVYWEEMLEKDVTALRKELKITLPPDLRTMRKERAALRKEIDAKYNSQKRATTP
                     A"
     gene            <859346..>861520
                     /gene="MSC2"
                     /locus_tag="YDR205W"
                     /db_xref="GeneID:851786"
     mRNA            <859346..>861520
                     /gene="MSC2"
                     /locus_tag="YDR205W"
                     /product="metal cation transporter MSC2"
                     /transcript_id="NM_001180513.3"
                     /db_xref="GI:398366086"
                     /db_