LOCUS NC_001136 1531933 bp DNA linear PLN 25-FEB-2013
DEFINITION Saccharomyces cerevisiae S288c chromosome IV, complete sequence.
ACCESSION NC_001136
VERSION NC_001136.10 GI:330443520
DBLINK Project: 128
KEYWORDS TPA:inferential.
SOURCE Saccharomyces cerevisiae S288c
ORGANISM Saccharomyces cerevisiae S288c
Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina;
Saccharomycetes; Saccharomycetales; Saccharomycetaceae;
Saccharomyces.
REFERENCE 1 (bases 1 to 1531933)
AUTHORS Jacq,C., Alt-Morbe,J., Andre,B., Arnold,W., Bahr,A., Ballesta,J.P.,
Bargues,M., Baron,L., Becker,A., Biteau,N., Blocker,H., Blugeon,C.,
Boskovic,J., Brandt,P., Bruckner,M., Buitrago,M.J., Coster,F.,
Delaveau,T., del Rey,F., Dujon,B., Eide,L.G.,
Garcia-Cantalejo,J.M., Goffeau,A., Gomez-Peris,A., Zaccaria,P. et
al.
TITLE The nucleotide sequence of Saccharomyces cerevisiae chromosome IV
JOURNAL Nature 387 (6632 SUPPL), 75-78 (1997)
PUBMED 9169867
REFERENCE 2 (bases 1 to 1531933)
AUTHORS Goffeau,A., Barrell,B.G., Bussey,H., Davis,R.W., Dujon,B.,
Feldmann,H., Galibert,F., Hoheisel,J.D., Jacq,C., Johnston,M.,
Louis,E.J., Mewes,H.W., Murakami,Y., Philippsen,P., Tettelin,H. and
Oliver,S.G.
TITLE Life with 6000 genes
JOURNAL Science 274 (5287), 546 (1996)
PUBMED 8849441
REFERENCE 3 (bases 1 to 1531933)
CONSRTM NCBI Genome Project
TITLE Direct Submission
JOURNAL Submitted (14-FEB-2013) National Center for Biotechnology
Information, NIH, Bethesda, MD 20894, USA
REFERENCE 4 (bases 1 to 1531933)
CONSRTM Saccharomyces Genome Database
TITLE Direct Submission
JOURNAL Submitted (06-FEB-2013) Department of Genetics, Stanford
University, Stanford, CA 94305-5120, USA
REMARK Protein update by submitter
REFERENCE 5 (bases 1 to 1531933)
CONSRTM Saccharomyces Genome Database
TITLE Direct Submission
JOURNAL Submitted (04-MAY-2012) Department of Genetics, Stanford
University, Stanford, CA 94305-5120, USA
REMARK Protein update by submitter
REFERENCE 6 (bases 1 to 1531933)
CONSRTM Saccharomyces Genome Database
TITLE Direct Submission
JOURNAL Submitted (31-MAR-2011) Department of Genetics, Stanford
University, Stanford, CA 94305-5120, USA
REMARK Sequence update by submitter
REFERENCE 7 (bases 1 to 1531933)
CONSRTM Saccharomyces Genome Database
TITLE Direct Submission
JOURNAL Submitted (11-DEC-2009) Department of Genetics, Stanford
University, Stanford, CA 94305-5120, USA
COMMENT PROVISIONAL REFSEQ: This record has not yet been subject to final
NCBI review. The reference sequence is identical to BK006938.
On Apr 26, 2011 this sequence version replaced gi:269970296.
Sequence assembly version R64-1-1.
COMPLETENESS: full length.
PRIMARY REFSEQ_SPAN PRIMARY_IDENTIFIER PRIMARY_SPAN COMP
1-5984 Z74296.1 1-5984
2954-8682 Z74295.1 1-5729
7815-11656 Z74294.1 1-3842
9757-16203 Z74293.1 1-6447
13361-17576 Z74292.1 1-4216
17227-18958 Z74291.1 1-1732
18567-20634 Z74290.1 1-2068
19313-22822 Z74289.1 1-3510
21007-26402 Z74288.1 1-5396
25877-28984 Z74287.1 1-3108
28776-30656 Z74286.1 1-1881
30455-32295 Z74285.1 1-1841
31830-33414 Z74284.1 1-1585
33235-34236 Z74283.1 1-1003
33919-36796 Z74282.1 1-2879
35232-38486 Z74281.1 1-3255
38174-38866 Z74280.1 1-693
38598-42699 Z74279.1 1-4102
42245-44064 Z74278.1 1-1820
43708-46270 Z74277.1 1-2563
45919-51114 Z74275.1 1-5196
48032-52444 Z74274.1 1-4413
52174-54396 Z74273.1 1-2223
54101-57264 Z74272.1 1-3164
56347-60871 Z74271.1 1-4525
60406-62010 Z74270.1 1-1605
61802-65241 Z74269.1 1-3440
65019-66492 Z74267.1 1-1474
65766-67982 Z74266.1 1-2217
67348-68996 Z74265.1 1-1649
68607-70639 Z74264.1 1-2033
70365-74445 Z74263.1 1-4081
73919-77288 Z74262.1 1-3370
76546-78425 Z74261.1 1-1880
77967-79293 Z74260.1 1-1327
79059-84269 Z74259.1 1-5211
80413-86206 Z74258.1 1-5794
85986-87460 Z74257.1 1-1475
87227-88247 Z74256.1 1-1021
87983-90175 Z74255.1 1-2193
89865-92761 Z74254.1 1-2897
92465-94604 Z74253.1 1-2140
93746-96081 Z74252.1 1-2336
95787-98474 Z74251.1 1-2688
97954-99560 Z74250.1 1-1607
99225-100500 Z74249.1 1-1276
100422-101289 Z74248.1 1-868
100664-103648 Z74247.1 1-2985
103354-104916 Z74246.1 1-1563
104552-106740 Z74245.1 1-2189
106495-107207 Z74244.1 1-713
107071-111579 Z74243.1 1-4509
111030-114671 Z74242.1 1-3642
114235-116320 Z74241.1 1-2086
115800-117663 Z74240.1 1-1864
116867-118706 Z74239.1 1-1840
118518-121977 Z74238.1 1-3460
121593-123864 Z74237.1 1-2272
123590-125508 Z74236.1 1-1919
124999-126786 Z74235.1 1-1788
126450-130406 Z74233.1 1-3957
130003-130870 Z74232.1 1-868
130485-133436 Z74231.1 1-2952
131834-135178 Z74230.1 1-3345
133958-135895 Z74229.1 1-1938
135437-138290 Z74228.1 1-2854
137540-139521 Z74227.1 1-1982
139206-141208 Z74226.1 1-2003
141115-142096 Z74225.1 1-982
141722-144483 Z74224.1 1-2762
144224-145825 Z74223.1 1-1602
145519-148190 Z74222.1 1-2672
147590-149202 Z74221.1 1-1613
149087-156317 Z74219.1 1-7231
155641-158063 Z74218.1 1-2423
157905-159603 Z74217.1 1-1699
158736-160994 Z74216.1 1-2259
160765-163448 Z74215.1 1-2684
163155-164289 Z74214.1 1-1135
164043-164986 Z74213.1 1-944
164866-167358 Z74212.1 1-2493
167259-170409 Z74210.1 1-3151
169079-172480 Z74208.1 1-3402
171931-174231 Z74207.1 1-2301
174175-174917 Z74205.1 1-743
174589-176772 Z74204.1 1-2184
176487-178333 Z74203.1 1-1847
178057-181185 Z74202.1 1-3129
181040-183317 Z74201.1 1-2278
183188-184924 Z74199.1 1-1737
184612-188153 Z74197.1 1-3542
187919-190923 Z74196.1 1-3005
190587-192749 Z74195.1 1-2163
192262-194570 Z74194.1 1-2309
194226-198661 Z74193.1 1-4436
194953-199995 Z74192.1 1-5043
199742-201718 Z74191.1 1-1977
201583-203038 Z74190.1 1-1456
202571-205359 Z74189.1 1-2789
205112-211374 Z74188.1 1-6263
210562-213350 Z74187.1 1-2789
212119-216528 Z74186.1 1-4409
215643-217599 Z74185.1 1-1956
217075-218679 Z74184.1 1-1605
218368-219661 Z74183.1 1-1294
219289-222426 Z74182.1 1-3138
220772-224303 Z74181.1 1-3532
222523-227392 Z74180.1 1-4870
226752-229905 Z74179.1 1-3154
228716-231023 Z74178.1 1-2308
230528-232651 Z74177.1 1-2124
231900-234926 Z74176.1 1-3027
233888-236156 Z74175.1 1-2268
235768-239018 Z74174.1 1-3251
238665-240258 Z74173.1 1-1594
239607-241417 Z74172.1 1-1811
241198-242551 Z74171.1 1-1354
241841-245132 Z74170.1 1-3292
244982-245922 Z74169.1 1-941
245583-246688 Z74168.1 1-1106
246448-248580 Z74167.1 1-2133
247683-251565 Z74165.1 1-3883
251239-253994 Z74164.1 1-2756
253747-255603 Z74163.1 1-1857
254718-256632 Z74162.1 1-1915
256531-258914 Z74161.1 1-2384
258556-263312 Z74160.1 1-4757
261776-264511 Z74159.1 1-2736
264111-265257 Z74158.1 1-1147
264965-267697 Z74157.1 1-2733
267202-268920 Z74156.1 1-1719
268700-270221 Z74155.1 1-1522
269977-272388 Z74154.1 1-2412
271902-273652 Z74153.1 1-1751
273598-275147 Z74152.1 1-1550
274877-276871 Z74151.1 1-1995
276582-280306 Z74150.1 1-3725
280166-282111 Z74149.1 1-1946
281849-283418 Z74148.1 1-1570
283177-284580 Z74147.1 1-1404
284445-285390 Z74146.1 1-946
285166-286997 Z74145.1 1-1832
286696-289571 Z74144.1 1-2876
289513-292780 Z74142.1 1-3268
292141-293391 Z74140.1 1-1251
292901-295033 Z74139.1 1-2133
294760-296819 Z74138.1 1-2060
296330-298416 Z74137.1 1-2087
298275-300213 Z74136.1 1-1939
300004-301412 Z74135.1 1-1409
301000-303210 Z74134.1 1-2211
302235-305236 Z74133.1 1-3002
304849-306925 Z74132.1 1-2077
306578-308423 Z74131.1 1-1846
307790-309801 Z74130.1 1-2012
309389-310641 Z74129.1 1-1253
310123-312950 Z74128.1 1-2828
312472-315356 Z74127.1 1-2885
314749-316970 Z74126.1 1-2222
316389-320667 Z74125.1 1-4279
320121-322225 Z74124.1 1-2105
321553-324046 Z74123.1 1-2494
322989-326612 Z74122.1 1-3624
326150-329835 Z74121.1 1-3686
329568-330665 Z74120.1 1-1099
330047-333120 Z74119.1 1-3074
332941-334216 Z74117.1 1-1275
333830-334834 Z74115.1 1-1005
334397-336248 Z74114.1 1-1852
336122-337486 Z74113.1 1-1365
337302-338271 Z74112.1 1-970
338071-340627 Z74111.1 1-2557
340002-341618 Z74109.1 1-1617
340799-344236 Z74108.1 1-3438
343986-345664 Z74107.1 1-1679
344954-351433 Z74106.1 1-6480
347229-352876 Z74105.1 1-5648
352421-355673 Z74104.1 1-3253
355379-359824 Z74103.1 1-4446
356760-361698 Z74102.1 1-4939
361286-362671 Z74101.1 1-1386
362257-363951 Z74100.1 1-1695
363584-365067 Z74099.1 1-1484
364818-366738 Z74097.1 1-1921
365875-369770 Z74096.1 1-3894
367701-371239 Z74095.1 1-3536
370707-372687 Z74094.1 1-1980
371762-373966 Z74093.1 1-2205
373609-375679 Z74092.1 1-2071
375290-376756 Z74091.1 1-1467
376481-378873 Z74090.1 1-2393
378456-381984 Z74088.1 1-3530
381439-384600 Z74087.1 1-3162
384082-387512 Z74085.1 1-3431
385588-389171 Z74084.1 1-3584
388902-392658 Z74083.1 1-3757
392128-394216 Z74081.1 1-2089
394002-397536 Z74079.1 1-3535
397205-399339 Z74078.1 1-2135
399130-400996 Z74077.1 1-1867
400639-403694 Z74076.1 1-3056
403292-405343 Z74075.1 1-2052
405061-408450 Z74073.1 1-3390
407207-411760 Z74072.1 1-4554
409858-413952 Z74071.1 1-4095
413001-415112 Z74069.1 1-2112
414889-417662 Z74068.1 1-2774
416709-422832 Z74067.1 1-6124
420773-424208 Z74066.1 1-3436
423511-426001 Z74065.1 1-2491
425873-427363 Z74063.1 1-1491
426935-429066 Z74062.1 1-2132
427883-431107 Z74061.1 1-3225
430927-432307 Z74060.1 1-1381
431518-433496 Z74059.1 1-1979
433233-438046 Z74056.1 1-4814
433995-439908 Z74055.1 1-5914
439361-441013 Z74054.1 1-1653
440407-477810 Z48008.1 1-37404
440755-443028 Z74053.1 1-2274
443029-470424 "ATGT...GTAA" 1-27396
470425-473156 Z74308.1 1-2732
473157-475989 "ATGT...ATAA" 1-2833
475990-478473 Z74311.1 1-2483
477677-488627 Z49770.1 1-10951
478200-479114 Z74312.1 1-915
478759-482669 Z74313.1 1-3911
480292-484162 Z74314.1 1-3871
483861-485745 Z74315.1 1-1885
485366-486803 Z74316.1 1-1438
486445-488071 Z74317.1 1-1627
488004-489507 Z74318.1 1-1504
488449-503273 Z47814.1 1-14825
488663-491016 Z74319.1 1-2354
490897-491514 Z74320.1 1-618
491145-492555 Z74321.1 1-1411
492325-494648 Z74322.1 1-2324
494269-497834 Z74323.1 1-3566
497835-501414 "CTAA...GTGA" 1-3580
501415-503497 Z74326.1 1-2083
503267-527893 Z68196.1 1-24628
503274-504098 Z74327.1 1-824
504099-512109 "TCAA...ACAT" 1-8011
512110-523210 Z74331.1 1-11101
523211-527215 "TTAT...TTAA" 1-4005
527216-531306 Z74334.1 1-4091
527894-535191 Z74335.1 1-7298
531779-541777 Z54075.1 1-9999
541755-547918 Z49812.1 1-6165
547831-588929 Z49209.1 1-41099
565641-567722 Z74353.1 1-2082
567723-578159 "TTAA...TTGA" 1-10437
578160-579457 Z74359.1 1-1299
579113-580686 Z74360.1 1-1574
580687-583465 "ATGG...TCAT" 1-2779
583466-584938 Z74364.1 1-1473
584132-622891 Z46796.1 1-38760
589403-592438 Z74368.1 1-3035
589772-593892 Z74369.1 1-4120
593893-603399 "ATGA...ATGA" 1-9507
603400-607303 Z74376.1 1-3904
607304-609162 "CTAA...TTTT" 1-1859
609163-612015 Z74378.1 1-2853
612016-617170 "ATGC...CCAT" 1-5155
617171-618496 Z74383.1 1-1326
618307-622111 Z74384.1 1-3805
619132-625065 Z74385.1 1-5934
622854-631313 Z50111.1 1-8460
631241-667457 Z47746.1 1-36217
665212-704024 Z48758.1 1-38813
703670-741221 Z48179.1 1-37552
741200-745540 Z54139.1 1-4341
745514-788981 Z50046.1 1-43468
787984-801614 Z47813.1 1-13631
800596-839930 Z46727.1 1-39334
838927-858162 Z48784.1 1-19236
858126-897953 Z68194.1 1-39827
897516-932101 Z48612.1 1-34586
932083-962589 Z49701.1 1-30507
962590-986590 Z68329.1 1-24000
962590-981170 Z70202.1 1-18581
979210-994241 Z74387.1 1-15032
992643-996304 Z70202.1 18592-22253
992754-996304 Z68290.1 1-3551
995078-1030143 U51030.1 1-35066
1027544-1052485 U51031.1 1-24942
1051686-1095571 U28374.1 1-43887
1095372-1134546 U32517.2 1-39173
1133147-1172460 U51032.1 1-39313
1172061-1203242 U28372.1 1-31184
1202643-1244775 U28373.1 1-42133
1237261-1292619 U32274.1 1-55359
1291770-1370269 U33007.1 1-78500
1369270-1438278 U33050.4 1-69009
1437729-1509848 U33057.1 1-72119
1509733-1527005 U43834.1 1-17267
1526028-1531933 Z74389.1 1-5906
FEATURES Location/Qualifiers
source 1..1531933
/organism="Saccharomyces cerevisiae S288c"
/mol_type="genomic DNA"
/strain="S288c"
/db_xref="taxon:559292"
/chromosome="IV"
telomere complement(1..904)
/note="TEL04L; Telomeric region on the left arm of
Chromosome IV; composed of an X element core sequence, X
element combinatorial repeats, and a terminal stretch of
telomeric repeats"
/db_xref="SGD:S000028875"
repeat_region complement(1..154)
/note="TEL04L-TR; Terminal stretch of telomeric repeats on
the left arm of Chromosome IV"
/rpt_family="Telomeric Repeat"
/db_xref="SGD:S000028876"
rep_origin 137..1392
/note="ARS400;
Autonomously Replicating Sequence"
/db_xref="SGD:S000121226"
repeat_region complement(155..434)
/note="TEL04L-XR; Telomeric X element combinatorial Repeat
region on the left arm of Chromosome IV, spans 279 bp and
contains repeats of the D, C, B and A types, as well as
Tbf1p binding sites; formerly called SubTelomeric Repeats"
/rpt_family="X element Combinatorial Repeats"
/db_xref="SGD:S000028878"
repeat_region complement(435..904)
/note="TEL04L-XC; Telomeric X element Core sequence on the
left arm of Chromosome IV, spans 469 bp and contains an
ARS consensus sequence and an Abf1p binding site consensus
sequence"
/rpt_family="X element Core sequence"
/db_xref="SGD:S000028877"
gene 1802..2953
/gene="COS7"
/locus_tag="YDL248W"
/db_xref="GeneID:851348"
mRNA 1802..2953
/gene="COS7"
/locus_tag="YDL248W"
/product="Cos7p"
/transcript_id="NM_001180308.1"
/db_xref="GI:296143127"
/db_xref="GeneID:851348"
CDS 1802..2953
/gene="COS7"
/locus_tag="YDL248W"
/note="hypothetical protein, member of the DUP380
subfamily of conserved, often subtelomerically-encoded
proteins; the authentic, non-tagged protein is detected in
highly purified mitochondria in high-throughput studies"
/codon_start=1
/product="Cos7p"
/protein_id="NP_010033.1"
/db_xref="GI:6319953"
/db_xref="SGD:S000002407"
/db_xref="GeneID:851348"
/translation="MKENEVKDEKSVDVLSFKQLESQKIVLPQDLFRSSFTWFCYEIY
KSLAFRIWMLLWLPLSVWWKLSNNCIYPLIVSLLVLFLGPIFVLVICGLSRKRSLSKQ
LIQFCKEITENTPSSDPHDWEVVVANLNSYLYENKAWNTKNFFFNATDCEKMFRTTVL
EPFSLKKDKAAKVKSFKDSVPYIEEALQVYATGFDKQWKLFITEKSWSPVGLEDVQLP
KDIHRSKLTWFLKRIFTIYSLPLWLAFLNCICVSQHFCLAFRILCPGLFFLMMVWLFQ
NMRTTALLVKMEHKMQFLLTIINEQESGANGWDEIARKMNRYLFEKKAWKNEEFFFDG
IDCEWFFSHFFYRLLSAKKSMWLLPLNVELWPYIKEAQLSRNEESLMKK"
gene 5985..7814
/gene="MPH2"
/locus_tag="YDL247W"
/db_xref="GeneID:851350"
mRNA 5985..7814
/gene="MPH2"
/locus_tag="YDL247W"
/product="Mph2p"
/transcript_id="NM_001180307.1"
/db_xref="GI:296143128"
/db_xref="GeneID:851350"
CDS 5985..7814
/gene="MPH2"
/locus_tag="YDL247W"
/note="Alpha-glucoside permease, transports maltose,
maltotriose, alpha-methylglucoside, and turanose;
identical to Mph3p; encoded in a subtelomeric position in
a region likely to have undergone duplication"
/codon_start=1
/product="Mph2p"
/protein_id="NP_010034.1"
/db_xref="GI:6319954"
/db_xref="SGD:S000002406"
/db_xref="GeneID:851350"
/translation="MKNLSFLINRRKENTSDSNVYPGKAKSHEPSWIEMDDQTKKDGL
DIVHVEFSPDTRAPSDSNKVITEIFDATEDAKEADESERGMPLATALNTYPKAAAWSL
LVSTTLIMEGYDTAILGAFYALPIFQRKFGSQNDKTGEWEISASWQIGLTLCYMAGEI
VGLQLTGPSVDLVGNRYTLIIALFFLAAFTFILYFCNSLGMIAVGQALCGMPWGCFQC
LTVSYASEICPLALRYYLTTYSNLCWLFGQLFAAGIMKNSQKKYADSELGYKLPFALQ
WILPVPLALGIFFAPESPWWLVKKGRFDEARRSLRRTLSGKGPEKEILVTLEVDKIKV
TIDKEKRLTSKEGSYSDCFEDKINRRRTRITCLCWAGQATCGSILIGYSTYFYEKAGV
STEMSFTFSIIQYCLGICATFLSWWASKYFGRYDLYAFGLAFQTIVFFIIGGLGCSST
HGSKMGSGSLLMAVAFFYNLGIAPVVFCLVSEMPSSRLRTKTIILARNTYNVVSIICS
VLILYQLNSKKWNWGAKSGFFWGVLCFCTLIWAVVDLPETAGKTFVEINELFKLGVSA
RKFKSTKVDPFVVKTPLKTSLITTPREISKLPLQRNSNVSHHL"
gene complement(8683..9756)
/gene="SOR2"
/locus_tag="YDL246C"
/db_xref="GeneID:851351"
mRNA complement(8683..9756)
/gene="SOR2"
/locus_tag="YDL246C"
/product="L-iditol 2-dehydrogenase SOR2"
/transcript_id="NM_001180306.1"
/db_xref="GI:296143129"
/db_xref="GeneID:851351"
CDS complement(8683..9756)
/gene="SOR2"
/locus_tag="YDL246C"
/EC_number="1.1.1.14"
/note="hypothetical protein; protein sequence is 99%
identical to the Sor1p sorbitol dehydrogenase;
computational analysis of large-scale protein-protein
interaction data also suggests a role in fructose or
mannose metabolism"
/codon_start=1
/product="L-iditol 2-dehydrogenase SOR2"
/protein_id="NP_010035.1"
/db_xref="GI:6319955"
/db_xref="SGD:S000002405"
/db_xref="GeneID:851351"
/translation="MSQNSNPAVVLEKVGDIAIEQRPIPTIKDPHYVKLAIKATGICG
SDIHYYRSGGIGKYILKAPMVLGHESSGQVVEVGDAVTRVKVGDRVAIEPGVPSRYSD
ETKEGSYNLCPHMAFAATPPIDGTLVKYYLSPEDFLVKLPEGVSYEEGACVEPLSVGV
HSNKLAGVRFGTKVVVFGAGPVGLLTGAVARAFGATDVIFVDVFDNKLQRAKDFGATN
TFNSSQFSTDKAQDLADGVQKLLGGNHADVVFECSGADVCIDAAVKTTKVGGTMVQVG
MGKNYTNFPIAEVSGKEMKLIGCFRYSFGDYRDAVNLVATGKVNVKPLITHKFKFEDA
AKAYDYNIAHGGEVVKTIIFGPE"
gene complement(11657..13360)
/gene="HXT15"
/locus_tag="YDL245C"
/db_xref="GeneID:851352"
mRNA complement(11657..13360)
/gene="HXT15"
/locus_tag="YDL245C"
/product="Hxt15p"
/transcript_id="NM_001180305.1"
/db_xref="GI:296143130"
/db_xref="GeneID:851352"
CDS complement(11657..13360)
/gene="HXT15"
/locus_tag="YDL245C"
/note="hypothetical protein with similarity to hexose
transporter family members, expression is induced by low
levels of glucose and repressed by high levels of glucose"
/codon_start=1
/product="Hxt15p"
/protein_id="NP_010036.1"
/db_xref="GI:6319956"
/db_xref="SGD:S000002404"
/db_xref="GeneID:851352"
/translation="MASEQSSPEINADNLNSSAADVHVQPPGEKEWSDGFYDKEVING
NTPDAPKRGFLGYLIIYLLCYPVSFGGFLPGWDSGITAGFINMDNFKMNFGSYKHSTG
EYYLSNVRMGLLVAMFSVGCSIGGVAFARLADTLGRRLAIVIVVLVYMVGAIIQISSN
HKWYQYFVGKIIYGLGAGGCSVLCPMLLSEIAPTDLRGGLVSLYQLNMTFGIFLGYCS
VYGTRKYSNTAQWRIPVGLCFLWALIIIVGMLLVPESPRYLIECERHEEACVSIAKIN
KVSPEDPWVLKQADEINAGVLAQRELGEASWKELFSVKTKVLQRLITGILVQTFLQLT
GENYFFFYGTTIFKSVGLTDGFETSIVLGTVNFFSTIIAVMVVDKIGRRKCLLFGAAS
MMACMVIFASIGVKCLYPHGQDGPSSKGAGNAMIVFTCFYIFCFATTWAPVAYIVVAE
SFPSKVKSKAMSISTAFNWLWQFLIGFFTPFITGSIHFYYGYVFVGCLVAMFLYVFFF
LPETIGLSLEEIQLLYEEGIKPWKSASWVPPSRRGASSRETEAKKKSWKEVLKFPKSF
N"
rep_origin 15493..15739
/note="ARS403;
Autonomously Replicating Sequence"
/db_xref="SGD:S000118427"
gene 16204..17226
/gene="THI13"
/locus_tag="YDL244W"
/db_xref="GeneID:851353"
mRNA 16204..17226
/gene="THI13"
/locus_tag="YDL244W"
/product="Thi13p"
/transcript_id="NM_001180304.1"
/db_xref="GI:296143131"
/db_xref="GeneID:851353"
CDS 16204..17226
/gene="THI13"
/locus_tag="YDL244W"
/note="Protein involved in synthesis of the thiamine
precursor hydroxymethylpyrimidine (HMP); member of a
subtelomeric gene family including THI5, THI11, THI12, and
THI13"
/codon_start=1
/product="Thi13p"
/protein_id="NP_010037.1"
/db_xref="GI:6319957"
/db_xref="SGD:S000002403"
/db_xref="GeneID:851353"
/translation="MSTDKITFLLNWQPTPYHIPIFLAQTKGYFKEQGLDIAILEPTN
PSDVTELIGSGKVDMGLKAMIHTLAAKARGFPVTSVASLLDEPFTGVLYLKGSGITED
FQSLKGKKIGYVGEFGKIQIDELTKHYGMKPEDYTAVRCGMNVAKYIIEGKIDAGIGI
ECMQQVELEEYLAKQGRPASDAKMLRIDKLACLGCCCFCTVLYICNDEFLKKNPEKVR
KFLKAIKKATDYVLADPVKAWKEYIDFKPQLNNDLSYKQYQRCYAYFSSSLYNVHRDW
KKVTGYGKRLAILPPDYVSNYTNEYLSWPEPEEVSDPLEAQRLMAIHQEKCRQEGTFK
RLALPA"
gene complement(17577..18566)
/gene="AAD4"
/locus_tag="YDL243C"
/db_xref="GeneID:851354"
mRNA complement(17577..18566)
/gene="AAD4"
/locus_tag="YDL243C"
/product="Aad4p"
/transcript_id="NM_001180303.1"
/db_xref="GI:296143132"
/db_xref="GeneID:851354"
CDS complement(17577..18566)
/gene="AAD4"
/locus_tag="YDL243C"
/EC_number="1.1.1.-"
/note="Putative aryl-alcohol dehydrogenase; involved in
oxidative stress response; similar to P. chrysosporium
aryl-alcohol dehydrogenase; expression induced in cells
treated with the mycotoxin patulin"
/codon_start=1
/product="Aad4p"
/protein_id="NP_010038.1"
/db_xref="GI:6319958"
/db_xref="SGD:S000002402"
/db_xref="GeneID:851354"
/translation="MGSMNKEQAFELLDAFYEAGGNCIDTANSYQNEESEIWIGEWMK
SRKLRDQIVIATKFTGDYKKYEVGGGKSANYCGNHKHSLHVSVRDSLRKLQTDWIDIL
YVHWWDYMSSIEEVMDSLHILVQQGKVLYLGVSDTPAWVVSAANYYATSHGKTPFSIY
QGKWNVLNRDFERDIIPMARHFGMALAPWDVMGGGRFQSKKAMEERKKNGEGLRTVSG
TSKQTDKEVKISEALAKVAEEHGTESVTAIAIAYVRSKAKNVFPLVGGRKIEHLKQNI
EALSIKLTPEQIEYLESIIPFDVGFPTNFIGDDPAVTKKASLLTAMSAQISFD"
gene 20635..21006
/locus_tag="YDL241W"
/db_xref="GeneID:851356"
mRNA 20635..21006
/locus_tag="YDL241W"
/product="hypothetical protein"
/transcript_id="NM_001180301.1"
/db_xref="GI:296143133"
/db_xref="GeneID:851356"
CDS 20635..21006
/locus_tag="YDL241W"
/note="hypothetical protein; YDL241W is not an essential
gene"
/codon_start=1
/product="hypothetical protein"
/protein_id="NP_010040.1"
/db_xref="GI:6319960"
/db_xref="SGD:S000002400"
/db_xref="GeneID:851356"
/translation="MNVTENALLFKCGSKGYINQTYTPTEIYNCGVAEGKKTAKEKNP
TYSIFYDTFLTGQPAESPETFTCGSHGFTNASYVASDFYACGFLQGKGTETNAGIHNT
RPSHSLAKFTILFMLVLYTIV"
gene 22823..25876
/gene="LRG1"
/locus_tag="YDL240W"
/db_xref="GeneID:851358"
mRNA 22823..25876
/gene="LRG1"
/locus_tag="YDL240W"
/product="Lrg1p"
/transcript_id="NM_001180300.2"
/db_xref="GI:330443490"
/db_xref="GeneID:851358"
CDS 22823..25876
/gene="LRG1"
/locus_tag="YDL240W"
/note="Putative GTPase-activating protein (GAP) involved
in the Pkc1p-mediated signaling pathway that controls cell
wall integrity; appears to specifically regulate
1,3-beta-glucan synthesis"
/codon_start=1
/product="Lrg1p"
/protein_id="NP_010041.2"
/db_xref="GI:330443491"
/db_xref="SGD:S000002399"
/db_xref="GeneID:851358"
/translation="MIQNSAGYRSLNTASPMTVQVKNQKKICARCNKLVIPDSQRTKT
TLKALGKYYHESCFTCQDCQKPLKPKYFPYQVDKTSESILLCQYDYFRRHNLLCHVCD
TPLRGLYYTAFGYRYDEEHFSCTICATPCGVKKCFMYGNQLYCKYHFLKYFSKRCKGC
EFPISDQYIEFPKGEEIHCWHPECYGIHKYWHVNLAAETVGLQYLPKLEYNPNSGDKD
INPTAYELDKQMQAFNFILSKTWSVLYRFEEEAASCISDMFQYLTSNDQLKGIESTGL
LVLKIDCLFRGLDTLNLSTNKSMPVNSDQECIENNAMAASKYSKFPKNLSTKIMIYLQ
LLRKLGTENKNETITISSFMSVITGLAHFLKLLTRFGLYTALENNKLTHSVNPLLRFL
REVEKNELFENNPFQYIKTPVNATDSCAGCNKYIQEECIQFYEHRWHIACFTCSSCHK
NINPRSLTDPTFNKEKKKILCSHCSIDDPASVPGFKFVTKLAQLIFLLKIALVKSRTV
MLKSKASNKVGRNSLQSTMLKEQTYIRTLNDIKRLRSRRESVRVTHNKQQARKSVILE
TAETDLNDPTKQGDSKNLVIQTDDPSSSQQVSTRENVFSNTKTLTLDDISRIVAAEQA
RELRPNAFAHFKKLKETDDETSNVVPKKSGVYYSELSTMELSMIRAISLSLLAGKQLI
SKTDPNYTSLVSMVFSNEKQVTGSFWNRMKIMMSMEPKKPITKTVFGAPLDVLCEKWG
VDSDLGVGPVKIRIPIIIDELISSLRQMDMSVEGIFRKNGNIRRLRELTANIDSNPTE
APDFSKENAIQLSALLKKFIRELPQPILSTDLYELWIKAAKIDLEDEKQRVILLIYSL
LPTYNRNLLEALLSFLHWTSSFSYIENEMGSKMDIHNLSTVITPNILYLRHKEISNDN
VPDEPESGLVDSFAQNKGENYFLAIEIVDYLITHNEEMAMVPKFLMNLLKDVQLQKLD
NYESINHFISTVMQSKTIDYSECDIKTPVTVKDSTTTVIQGEINK"
gene complement(26403..28775)
/gene="ADY3"
/locus_tag="YDL239C"
/db_xref="GeneID:851359"
mRNA complement(26403..28775)
/gene="ADY3"
/locus_tag="YDL239C"
/product="Ady3p"
/transcript_id="NM_001180299.2"
/db_xref="GI:330443492"
/db_xref="GeneID:851359"
CDS complement(26403..28775)
/gene="ADY3"
/locus_tag="YDL239C"
/note="Protein required for spore wall formation; thought
to mediate assembly of a Don1p-containing structure at the
leading edge of the prospore membrane via interaction with
spindle pole body components; potentially phosphorylated
by Cdc28p; ADY3 has a paralog, CNM67, that arose from the
whole genome duplication"
/codon_start=1
/product="Ady3p"
/protein_id="NP_010042.2"
/db_xref="GI:330443493"
/db_xref="SGD:S000002398"
/db_xref="GeneID:851359"
/translation="MNHWLAFLNKPESLKEQNSDCDQQGEMRHVTDGTLTKSPESKPF
RERRSQTWIDSEVPTSTEKSNVQESISSDIISKLSNRRSRRNRSESWAGSEASSPSGN
ISTLENATEKNTLKSPNKFLQRGGLPTVGIGSQALSPAGKPSTLGNVSPGKFTTYKVH
NSIEVNRFSSTPTKLLTNPHKVAAISNDEHYVVSNESLEENIEVAHLENVFRSSKTPD
EEQSEYMKLGEIRLSSSSYGGSISKENSLPKVLDELQSQNEEIKALRQKLEEKDDRIQ
ELEELNSMNDAKLQRIEDLQKEFHNERKAASKRLNIVQDRFRKEIKKIREEKITDFQN
KNASKKEKNEVTSAKTKCKAFSQRNILVSELYRKQKQILNLQQENDKFLKDINESNNS
IVKLRSEVEILKSNLQLSQDENKKLHDNGSFYEKRLNDVYSYMQNLSLFEKDLGKFIL
EEMKCGHSPSMFQNGFAKLYPDFQDIKNLENMEQYKQLKGKIELLEKNDRIRLEKIIS
VFKLINERLHFMQQQHSHKIKYLQKEALTKEQQFRLEKRRWHDILNLKEENFQKLKSE
LKEKLILSEKIQKNAEDKLNDYMNEHQEIVEKLQNQALIASRWSTQIQESENTHKKIT
DELAGKQSEILKLEETILSLKEDVFQEKLNLKKLYGDPSTELNFETVGKSFPHITKEK
YDSLGLDILTDLTYVQSQNLIKNLLIVLDIPLKTFLKIVPTIVIQLRCELTLLTKFAN
DLNLKVFGKQLDFKSRRKVAMNEFLNNHDIAEVKHPLEYDLQALFKYFFS"
gene complement(28985..30454)
/gene="GUD1"
/locus_tag="YDL238C"
/db_xref="GeneID:851360"
mRNA complement(28985..30454)
/gene="GUD1"
/locus_tag="YDL238C"
/product="guanine deaminase"
/transcript_id="NM_001180298.1"
/db_xref="GI:296143136"
/db_xref="GeneID:851360"
CDS complement(28985..30454)
/gene="GUD1"
/locus_tag="YDL238C"
/EC_number="3.5.4.3"
/note="Guanine deaminase, a catabolic enzyme of the
guanine salvage pathway producing xanthine and ammonia
from guanine; activity is low in exponentially-growing
cultures but expression is increased in post-diauxic and
stationary-phase cultures"
/codon_start=1
/product="guanine deaminase"
/protein_id="NP_010043.1"
/db_xref="GI:6319963"
/db_xref="SGD:S000002397"
/db_xref="GeneID:851360"
/translation="MTKSDLLFDKFNDKHGKFLVFFGTFVDTPKLGELRIREKTSVGV
LNGIIRFVNRNSLDPVKDCLDHDSSLSPEDVTVVDIIGKDKTRNNSFYFPGFVDTHNH
VSQYPNVGVFGNSTLLDWLEKYTFPIEAALANENIAREVYNKVISKTLSHGTTTVAYY
NTIDLKSTKLLAQLSSLLGQRVLVGKVCMDTNGPEYYIEDTKTSFESTVKVVKYIRET
ICDPLVNPIVTPRFAPSCSRELMQQLSKLVKDENIHVQTHLSENKEEIQWVQDLFPEC
ESYTDVYDKYGLLTEKTVLAHCIHLTDAEARVIKQRRCGISHCPISNSSLTSGECRVR
WLLDQGIKVGLGTDVSAGHSCSILTTGRQAFAVSRHLAMRETDHAKLSVSECLFLATM
GGAQVLRMDETLGTFDVGKQFDAQMIDTNAPGSNVDMFHWQLKEKDQMQEQEQEQGQD
PYKNPPLLTNEDIIAKWFFNGDDRNTTKVWVAGQQVYQI"
gene 30657..31829
/gene="AIM6"
/locus_tag="YDL237W"
/db_xref="GeneID:851361"
mRNA 30657..31829
/gene="AIM6"
/locus_tag="YDL237W"
/product="Aim6p"
/transcript_id="NM_001180297.2"
/db_xref="GI:330443494"
/db_xref="GeneID:851361"
CDS 30657..31829
/gene="AIM6"
/locus_tag="YDL237W"
/note="hypothetical protein, required for respiratory
growth; YDL237W is not an essential gene"
/codon_start=1
/product="Aim6p"
/protein_id="NP_010044.2"
/db_xref="GI:330443495"
/db_xref="SGD:S000002396"
/db_xref="GeneID:851361"
/translation="MLGLKGCLTILIGYVIAVCALFSSRGRNPSLTDWEKLKDQKISN
IDNFGLTGQHLLEFFQENLPFLSFSEEKYRHKHVSLYYDVFKEYILRRASSKKCLPVD
SAIAKLNKDVNPMPVHSHNDYWRKLPLFEGLAYGASSTEADVWNIDEKILAVGHNEAY
LDPVELTLDKLYTGPLLEILDEVNCQDSDADRKNGVFFNSPETSLFFYIDFKSDDNEL
TYKLLMEQYFKSLIDSGYLTYYDMKKDEIIWRPVTVILTGNYPTSLDILDNGNDNGYF
ESSQRFAFLDAPLLSLEPKYSKLSVAATVSFSQLMKHCGSDHWKVSLRGRMDSNEISC
AKSIIDGAHALKLKTRIWGAPTWPANLVETISRQIIHDLGSDLLNLDNLFMASSLI"
gene 32296..33234
/gene="PHO13"
/locus_tag="YDL236W"
/db_xref="GeneID:851362"
mRNA 32296..33234
/gene="PHO13"
/locus_tag="YDL236W"
/product="Pho13p"
/transcript_id="NM_001180296.1"
/db_xref="GI:296143138"
/db_xref="GeneID:851362"
CDS 32296..33234
/gene="PHO13"
/locus_tag="YDL236W"
/EC_number="3.1.3.41"
/note="Alkaline phosphatase specific for p-nitrophenyl
phosphate; also has protein phosphatase activity"
/codon_start=1
/product="Pho13p"
/protein_id="NP_010045.1"
/db_xref="GI:6319965"
/db_xref="SGD:S000002395"
/db_xref="GeneID:851362"
/translation="MTAQQGVPIKITNKEIAQEFLDKYDTFLFDCDGVLWLGSQALPY
TLEILNLLKQLGKQLIFVTNNSTKSRLAYTKKFASFGIDVKEEQIFTSGYASAVYIRD
FLKLQPGKDKVWVFGESGIGEELKLMGYESLGGADSRLDTPFDAAKSPFLVNGLDKDV
SCVIAGLDTKVNYHRLAVTLQYLQKDSVHFVGTNVDSTFPQKGYTFPGAGSMIESLAF
SSNRRPSYCGKPNQNMLNSIISAFNLDRSKCCMVGDRLNTDMKFGVEGGLGGTLLVLS
GIETEERALKISHDYPRPKFYIDKLGDIYTLTNNEL"
gene complement(33415..33918)
/gene="YPD1"
/locus_tag="YDL235C"
/db_xref="GeneID:851363"
mRNA complement(33415..33918)
/gene="YPD1"
/locus_tag="YDL235C"
/product="Ypd1p"
/transcript_id="NM_001180295.1"
/db_xref="GI:296143139"
/db_xref="GeneID:851363"
CDS complement(33415..33918)
/gene="YPD1"
/locus_tag="YDL235C"
/note="Phosphorelay intermediate protein, phosphorylated
by the plasma membrane sensor Sln1p in response to osmotic
stress and then in turn phosphorylates the response
regulators Ssk1p in the cytosol and Skn7p in the nucleus"
/codon_start=1
/product="Ypd1p"
/protein_id="NP_010046.1"
/db_xref="GI:6319966"
/db_xref="SGD:S000002394"
/db_xref="GeneID:851363"
/translation="MSTIPSEIINWTILNEIISMDDDDSDFSKGLIIQFIDQAQTTFA
QMQRQLDGEKNLTELDNLGHFLKGSSAALGLQRIAWVCERIQNLGRKMEHFFPNKTEL
VNTLSDKSIINGINIDEDDEEIKIQVDDKDENSIYLILIAKALNQSRLEFKLARIELS
KYYNTNL"
gene complement(34237..36477)
/gene="GYP7"
/locus_tag="YDL234C"
/db_xref="GeneID:851364"
mRNA complement(34237..36477)
/gene="GYP7"
/locus_tag="YDL234C"
/product="Gyp7p"
/transcript_id="NM_001180294.1"
/db_xref="GI:296143140"
/db_xref="GeneID:851364"
CDS complement(34237..36477)
/gene="GYP7"
/locus_tag="YDL234C"
/note="GTPase-activating protein for yeast Rab family
members including: Ypt7p (most effective), Ypt1p, Ypt31p,
and Ypt32p (in vitro); involved in vesicle mediated
protein trafficking"
/codon_start=1
/product="Gyp7p"
/protein_id="NP_010047.1"
/db_xref="GI:6319967"
/db_xref="SGD:S000002393"
/db_xref="GeneID:851364"
/translation="MSKILFCKSKVFLHPTSDARDNIAGFLLLTLEANKLSHQAILQY
IPESGLSTLEISKLLKHEAKVGTCPTSTPFVIENSINFSNLVNTSLGQAFEISLSQIY
CIQFRPPSPNGWYVGSLVIYPLTEQFTGFQPPVLFFHDQLCPSTTDKLKRLRKSMNPF
DDSDELYWGGVDLRNKINELMELKKSNLEPEFWLVNPSLNDLRNFVSKDLLESYNNSK
KDTTELATAGVKLNEKFQEWKWNVMSKIADVTTKSTNFIDSWLTNNSPIQKSQIDNEY
LQKLLNNEKVKQIEQDYDSARVYLANWSLGVKQEAERYQKQNKLFDSYRNNIFNDLNL
TDELSDTEINNALQRQFPLTEAKWNSLWDENDGRLRVTVNEVKDFIFHGGLENDSLRG
KVWGFLLEIYPWDSSQDERVQIDQTLAAEYDQLKLTWSKDFLQFDDEDEEEYWNDQLF
RISKDVRRCDRNLEIFQYNTIDGLPPPPQQLPANENNSTSPESANDESDDADDGVRNP
HLIHLQNILITYNVYNTNLGYVQGMTDLLSPIYVIMKEEWKTFWCFTHFMDIMERNFL
RDQSGIHEQMLTLVELVQLMLPELSEHLNKCDSGNLFFCFRMLLVWFKREFEMEDIMH
IWENFWTFYYSSQFQLFFMLAILQKNSQAILQHLNQFDQILKFFNELNGKLDWNDLMV
RAELLFKKFEKMMHVMERDLQNVSSSSSSSSTGVLPCQSERLTLLLSKKPIIRHEGQR
SKNSVK"
gene 36797..38173
/gene="MFG1"
/locus_tag="YDL233W"
/db_xref="GeneID:851365"
mRNA 36797..38173
/gene="MFG1"
/locus_tag="YDL233W"
/product="Mfg1p"
/transcript_id="NM_001180293.1"
/db_xref="GI:296143141"
/db_xref="GeneID:851365"
CDS 36797..38173
/gene="MFG1"
/locus_tag="YDL233W"
/note="Regulator of filamentous growth; interacts with
FLO11 promoter and regulates FLO11 expression; binds to
transcription factors Flo8p and Mss11p; green fluorescent
protein (GFP)-fusion protein localizes to the nucleus;
YDL233W is not an essential gene"
/codon_start=1
/product="Mfg1p"
/protein_id="NP_010048.1"
/db_xref="GI:6319968"
/db_xref="SGD:S000002392"
/db_xref="GeneID:851365"
/translation="MYQGPPQPPPQAVPMPYIVNNNTPPYPNGNINFPPTAQQNIPPT
VYPQQVPFPGQPQGGQFPQPSSEQQVFNQLPQVTQTFHNSAQNTNATGGPGSGSMPMF
TPVASFPHPMATAATAAAPLPRSASQASLSMLRVPYHVRKYLSNLAMLKLYEIINEVN
TAMGKIGLLSFWTELISDIFTPDAVIRYSKKSMTDYREFEFIIPVFPVICSTLGRFGI
VRMEVKVLQLKTQVLSNSTIFFNCPRVTFVYYYPDGSYITHFSQMKGAFDLDLKINWL
DVSMHSFVPDIEWNAVERLLSDDTKSTEIEQIFRKLKQEDVKEQGNSFAENNATNVPP
NFEAITQLRSYFDVFRNVSVFGTQEGLMRVMQISTVMSTLKNLRKFQIEKNIDSPVTA
LSAYIDADKKDSGSEPLHAKRRRNSGISPRTTTLGPNGNSNTSNEELPTSDVNDINKD
MTKKKMKF"
gene 38487..38597
/gene="OST4"
/locus_tag="YDL232W"
/db_xref="GeneID:851366"
mRNA 38487..38597
/gene="OST4"
/locus_tag="YDL232W"
/product="Ost4p"
/transcript_id="NM_001180292.1"
/db_xref="GI:296143142"
/db_xref="GeneID:851366"
CDS 38487..38597
/gene="OST4"
/locus_tag="YDL232W"
/EC_number="2.4.99.18"
/note="Subunit of the oligosaccharyltransferase complex of
the ER lumen, which catalyzes protein asparagine-linked
glycosylation; type I membrane protein required for
incorporation of Ost3p or Ost6p into the OST complex"
/codon_start=1
/product="Ost4p"
/protein_id="NP_010049.1"
/db_xref="GI:6319969"
/db_xref="SGD:S000002391"
/db_xref="GeneID:851366"
/translation="MISDEQLNSLAITFGIVMMTLIVIYHAVDSTMSPKN"
gene complement(38867..42244)
/gene="BRE4"
/locus_tag="YDL231C"
/db_xref="GeneID:851367"
mRNA complement(38867..42244)
/gene="BRE4"
/locus_tag="YDL231C"
/product="Bre4p"
/transcript_id="NM_001180291.1"
/db_xref="GI:296143143"
/db_xref="GeneID:851367"
CDS complement(38867..42244)
/gene="BRE4"
/locus_tag="YDL231C"
/note="Zinc finger protein containing five transmembrane
domains; null mutant exhibits strongly fragmented vacuoles
and sensitivity to brefeldin A, a drug which is known to
affect intracellular transport"
/codon_start=1
/product="Bre4p"
/protein_id="NP_010050.1"
/db_xref="GI:6319970"
/db_xref="SGD:S000002390"
/db_xref="GeneID:851367"
/translation="MKRYERDRSPTPDPDIVKGSYSQTSLRSLHELNYKNPAGISGLS
FAGSPQQSVASLSQMRLENLVKDKHWEEVEDFGLEELRDGFFDAAFTKPDSKARSPNS
DIDDDNGAARKKLQSGFTKLSEYVWTAIYRPIIHFPRDIRKNGVSIFKFFIAYFIAIV
ICVIRPSGRWIGHEFRYFLPIAVLIHHPVRNIGVQLEMTISSIIGASFGLGWSALAWY
ISTATKPTANYQGGILFQSLTMALLFAIWLRSVYRRFFYFTTSFSISIIFTHTVRLAS
SKFDLKWQIFWDFGISYLFGLLLSLLVCVCVSPHSGNAELMEHYNKCLQTTKTFLMAL
VDTELIKSKEQIYLAQVKMVKTLNIDLSQGFRDFVNQLTISRFDLQSLKSLRNSLTAM
ETSLRVLPIAPKIFNDDELKKMYEELEKYRSDSATLSKEASASPQSSGIPTRENTPSA
FKPIGPGLLKNEIYINALKASFSKSIFNLILEMIFVLENLSRVLKKYESPNQKNNLDE
CVKILSHSHSKLKRKIYKLDVCYRDFVNSSFFSQELLNDEESVDIFLFLRYLRNSARQ
LVTVIHDCQVLGENIHWRIALPSYPLSRALTRLPKQCVLDEGAGNVLHYFEAKRDVDE
IFERVYNTYTSRHKYNKGEEEALRLDSQGGDEKSQNRKNHTISIRAIDHNDFNFHTTQ
NPWRFKLWKLSRILSGDECKWTLKITFCMIFLCLPTWLPESYHWYQEFHCWWAPLTFY
LLAHRRYSGNWALVMRRLICGIVGIFWGWAANQSRHFGSPYVVCTFAGLIVVPFSINF
LVYRNTKSSFTALMCFTIIALEPYSKPNRHYNLTTAGIWKSTWVTGLALIIGILVSIP
INWIVWPFRARTELRDSMSSLLAHLGQSYQTVADRYLYRDADDAPTDLTFAFSHIREV
RLTQSLEAIRELLKKARHEPIIISNFNPEKYASLINSCQFLLSKIIEARISGAFFEIW
DQDFDIETTRALLSLRRDSVSSVIFVFYILSNCFRSKNKIPRYLPNPIMSRKKLYHFI
KKFSEMKDQSHSNLNSGGNSMEKNLFKKIYQQKASSSGQQQLPLPSVANSSEIDSEKM
HWTEVHGIAFARAFTDISEALFQVESCAKDILGEENF"
gene 42700..43707
/gene="PTP1"
/locus_tag="YDL230W"
/db_xref="GeneID:851368"
mRNA 42700..43707
/gene="PTP1"
/locus_tag="YDL230W"
/product="Ptp1p"
/transcript_id="NM_001180290.1"
/db_xref="GI:296143144"
/db_xref="GeneID:851368"
CDS 42700..43707
/gene="PTP1"
/locus_tag="YDL230W"
/EC_number="3.1.3.48"
/note="Phosphotyrosine-specific protein phosphatase that
dephosphorylates a broad range of substrates in vivo,
including Fpr3p; localized to the cytoplasm and the
mitochondria; proposed to be a negative regulator of
filamentation"
/codon_start=1
/product="Ptp1p"
/protein_id="NP_010051.1"
/db_xref="GI:6319971"
/db_xref="SGD:S000002389"
/db_xref="GeneID:851368"
/translation="MAAAPWYIRQRDTDLLGKFKFIQNQEDGRLREATNGTVNSRWSL
GVSIEPRNDARNRYVNIMPYERNRVHLKTLSGNDYINASYVKVNVPGQSIEPGYYIAT
QGPTRKTWDQFWQMCYHNCPLDNIVIVMVTPLVEYNREKCYQYWPRGGVDDTVRIASK
WESPGGANDMTQFPSDLKIEFVNVHKVKDYYTVTDIKLTPTDPLVGPVKTVHHFYFDL
WKDMNKPEEVVPIMELCAHSHSLNSRGNPIIVHCSAGVGRTGTFIALDHLMHDTLDFK
NITERSRHSDRATEEYTRDLIEQIVLQLRSQRMKMVQTKDQFLFIYHAAKYLNSLSVN
Q"
gene 44065..45906
/gene="SSB1"
/locus_tag="YDL229W"
/gene_synonym="YG101"
/db_xref="GeneID:851369"
mRNA 44065..45906
/gene="SSB1"
/locus_tag="YDL229W"
/gene_synonym="YG101"
/product="Ssb1p"
/transcript_id="NM_001180289.1"
/db_xref="GI:296143145"
/db_xref="GeneID:851369"
CDS 44065..45906
/gene="SSB1"
/locus_tag="YDL229W"
/gene_synonym="YG101"
/note="Cytoplasmic ATPase that is a ribosome-associated
molecular chaperone, functions with J-protein partner
Zuo1p; may be involved in folding of newly-made
polypeptide chains; member of the HSP70 family; interacts
with phosphatase subunit Reg1p"
/codon_start=1
/product="Hsp70 family ATPase SSB1"
/protein_id="NP_010052.1"
/db_xref="GI:6319972"
/db_xref="SGD:S000002388"
/db_xref="GeneID:851369"
/translation="MAEGVFQGAIGIDLGTTYSCVATYESSVEIIANEQGNRVTPSFV
AFTPEERLIGDAAKNQAALNPRNTVFDAKRLIGRRFDDESVQKDMKTWPFKVIDVDGN
PVIEVQYLEETKTFSPQEISAMVLTKMKEIAEAKIGKKVEKAVITVPAYFNDAQRQAT
KDAGAISGLNVLRIINEPTAAAIAYGLGAGKSEKERHVLIFDLGGGTFDVSLLHIAGG
VYTVKSTSGNTHLGGQDFDTNLLEHFKAEFKKKTGLDISDDARALRRLRTAAERAKRT
LSSVTQTTVEVDSLFDGEDFESSLTRARFEDLNAALFKSTLEPVEQVLKDAKISKSQI
DEVVLVGGSTRIPKVQKLLSDFFDGKQLEKSINPDEAVAYGAAVQGAILTGQSTSDET
KDLLLLDVAPLSLGVGMQGDMFGIVVPRNTTVPTIKRRTFTTCADNQTTVQFPVYQGE
RVNCKENTLLGEFDLKNIPMMPAGEPVLEAIFEVDANGILKVTAVEKSTGKSSNITIS
NAVGRLSSEEIEKMVNQAEEFKAADEAFAKKHEARQRLESYVASIEQTVTDPVLSSKL
KRGSKSKIEAALSDALAALQIEDPSADELRKAEVGLKRVVTKAMSSR"
rep_origin 45918..46271
/note="ARS404;
Autonomously Replicating Sequence"
/db_xref="SGD:S000114787"
gene complement(46271..48031)
/gene="HO"
/locus_tag="YDL227C"
/db_xref="GeneID:851371"
mRNA complement(46271..48031)
/gene="HO"
/locus_tag="YDL227C"
/product="Hop"
/transcript_id="NM_001180287.1"
/db_xref="GI:296143146"
/db_xref="GeneID:851371"
CDS complement(46271..48031)
/gene="HO"
/locus_tag="YDL227C"
/note="Site-specific endonuclease required for gene
conversion at the MAT locus (homothallic switching)
through the generation of a ds DNA break; expression
restricted to mother cells in late G1 as controlled by
Swi4p-Swi6p, Swi5p and Ash1p"
/codon_start=1
/product="Hop"
/protein_id="NP_010054.1"
/db_xref="GI:6319974"
/db_xref="SGD:S000002386"
/db_xref="GeneID:851371"
/translation="MLSENTTILMANGEIKDIANVTANSYVMCADGSAARVINVTQGY
QKIYNIQQKTKHRAFEGEPGRLDPRRRTVYQRLALQCTAGHKLSVRVPTKPLLEKSGR
NATKYKVRWRNLQQCQTLDGRIIIIPKNHHKTFPMTVEGEFAAKRFIEEMERSKGEYF
NFDIEVRDLDYLDAQLRISSCIRFGPVLAGNGVLSKFLTGRSDLVTPAVKSMAWMLGL
WLGDSTTKEPEISVDSLDPKLMESLRENAKIWGLYLTVCDDHVPLRAKHVRLHYGDGP
DENRKTRNLRKNNPFWKAVTILKFKRDLDGEKQIPEFMYGEHIEVREAFLAGLIDSDG
YVVKKGEGPESYKIAIQTVYSSIMDGIVHISRSLGMSATVTTRSAREEIIEGRKVQCQ
FTYDCNVAGGTTSQNVLSYCRSGHKTREVPPIIKREPVYFSFTDDFQGESTVYGLTIE
GHKNFLLGNKIEVKSCRGCCVGEQLKISQKKNLKHCVACPRKGIKYFYKDWSGKNRVC
ARCYGRYKFSGHHCINCKYVPEAREVKKAKDKGEKLGITPEGLPVKGPECIKCGGILQ
FDAVRGPHKSCGNNAGARIC"
gene complement(51115..52173)
/gene="GCS1"
/locus_tag="YDL226C"
/db_xref="GeneID:851372"
mRNA complement(51115..52173)
/gene="GCS1"
/locus_tag="YDL226C"
/product="Gcs1p"
/transcript_id="NM_001180286.1"
/db_xref="GI:296143147"
/db_xref="GeneID:851372"
CDS complement(51115..52173)
/gene="GCS1"
/locus_tag="YDL226C"
/note="ADP-ribosylation factor GTPase activating protein
(ARF GAP), involved in ER-Golgi transport; shares
functional similarity with Glo3p"
/codon_start=1
/product="Gcs1p"
/protein_id="NP_010055.1"
/db_xref="GI:6319975"
/db_xref="SGD:S000002385"
/db_xref="GeneID:851372"
/translation="MSDWKVDPDTRRRLLQLQKIGANKKCMDCGAPNPQWATPKFGAF
ICLECAGIHRGLGVHISFVRSITMDQFKPEELLRMEKGGNEPLTEWFKSHNIDLSLPQ
KVKYDNPVAEDYKEKLTCLCEDRVFEEREHLDFDASKLSATSQTAASATPGVAQSREG
TPLENRRSATPANSSNGANFQKEKNEAYFAELGKKNQSRPDHLPPSQGGKYQGFGSTP
AKPPQERSAGSSNTLSLENFQADPLGTLSRGWGLFSSAVTKSFEDVNETVIKPHVQQW
QSGELSEETKRAAAQFGQKFQETSSYGFQAFSNFTKNFNGNAEDSSTAGNTTHTEYQK
IDNNDKKNEQDEDKWDDF"
gene 52445..54100
/gene="SHS1"
/locus_tag="YDL225W"
/gene_synonym="SEP7"
/db_xref="GeneID:851373"
mRNA 52445..54100
/gene="SHS1"
/locus_tag="YDL225W"
/gene_synonym="SEP7"
/product="septin SHS1"
/transcript_id="NM_001180285.1"
/db_xref="GI:296143148"
/db_xref="GeneID:851373"
CDS 52445..54100
/gene="SHS1"
/locus_tag="YDL225W"
/gene_synonym="SEP7"
/note="Component of the septin ring that is required for
cytokinesis; septins are GTP-binding proteins that
assemble into rod-like hetero-oligomers that can associate
with other rods to form filaments; septin rings at the
mother-bud neck act as scaffolds for recruiting cell
division factors and as barriers to prevent diffusion of
specific proteins; undergoes sumoylation and
phosphorylation during mitosis; protein abundance
increases in response to DNA replication stress"
/codon_start=1
/product="septin SHS1"
/protein_id="NP_010056.1"
/db_xref="GI:6319976"
/db_xref="SGD:S000002384"
/db_xref="GeneID:851373"
/translation="MSTASTPPINLFRRKKEHKRGITYTMLLCGPAGTGKTAFANNLL
ETKIFPHKYQYGKSNASISSNPEVKVIAPTKVVSFNSKNGIPSYVSEFDPMRANLEPG
ITITSTSLELGGNKDQGKPEMNEDDTVFFNLIMTHGIGENLDDSLCSEEVMSYLEQQF
DIVLAEETRIKRNPRFEDTRVHVALYFIEPTGHGLREVDVELMKSISKYTNVLPIITR
ADSFTKEELTQFRKNIMFDVERYNVPIYKFEVDPEDDDLESMEENQALASLQPFAIIT
SDTRDSEGRYVREYPWGIISIDDDKISDLKVLKNVLFGSHLQEFKDTTQNLLYENYRS
EKLSSVANAEEIGPNSTKRQSNAPSLSNFASLISTGQFNSSQTLANNLRADTPRNQVS
GNFKENEYEDNGEHDSAENEQEMSPVRQLGREIKQENENLIRSIKTESSPKFLNSPDL
PERTKLRNISETVPYVLRHERILARQQKLEELEAQSAKELQKRIQELERKAHELKLRE
KLINQNKLNGSSSSINSLQQSTRSQIKKNDTYTDLASIASGRD"
gene complement(54397..56346)
/gene="WHI4"
/locus_tag="YDL224C"
/db_xref="GeneID:851302"
mRNA complement(54397..56346)
/gene="WHI4"
/locus_tag="YDL224C"
/product="Whi4p"
/transcript_id="NM_001180284.1"
/db_xref="GI:296143149"
/db_xref="GeneID:851302"
CDS complement(54397..56346)
/gene="WHI4"
/locus_tag="YDL224C"
/note="Putative RNA binding protein and partially
redundant Whi3p homolog that regulates the cell size
requirement for passage through Start and commitment to
cell division"
/codon_start=1
/product="Whi4p"
/protein_id="NP_010057.1"
/db_xref="GI:6319977"
/db_xref="SGD:S000002383"
/db_xref="GeneID:851302"
/translation="MSLVHNQTNLNESKFLIERAFSSSSETVPLSKEATYPMPTAYSF
SAVRSNSETNIKRENPQGFAKEPIMTSMLHNLTMSTGKGNGNDVNSLAPHDVDVGPYC
LLLRNLPKDITLRECYCIFSLATGVSSIELKRDDREPFNDNEKVVVVKFGSLSLVTHY
ANILNSKSEIFGPSFPFRSHIDVVNEQTQLPVSFQEHVSSGTTNSSPKNYQLSSSAQN
EIQNQSFNTISYGKTSSSPLGPSAAKPRPSLLSERSLRFSFNDPFGLETISQRKESVP
FLRNSISQHDLSNVTTTPVPAGMPPQKDAGKSLLLLEKDEINESIWNGDELVNDVGNS
SFGASLQEPPMSSTPVMEWNASSTANIPLFQLSSQENHQSNLLPPSHHSISQDVPHIQ
SQPNLNNSGVIHSATSLPHYHLLNQINASTKTQSIQQSVSNVPSNLDLNLQTENGHPQ
SSAPNGSSIFNNQKVNQGFLVSEQDTSTISRQKECSSTASASAFSKNNETNVAGSTTI
SQADLSLLAKVPPPANPADQNPPCNTLYVGNLPPDATEQELRQLFSNQQGFRRLSFRN
KMNSHGHGNGHGHGPICFVEFEDVSFATRALAELYGSQLPHPRPSLNNKGGIRLSFSK
NPLGVRGSNSRSKSGYSFNGSYGKS"
gene complement(57265..60405)
/gene="HBT1"
/locus_tag="YDL223C"
/db_xref="GeneID:851303"
mRNA complement(57265..60405)
/gene="HBT1"
/locus_tag="YDL223C"
/product="Hbt1p"
/transcript_id="NM_001180283.1"
/db_xref="GI:296143150"
/db_xref="GeneID:851303"
CDS complement(57265..60405)
/gene="HBT1"
/locus_tag="YDL223C"
/note="Substrate of the Hub1p ubiquitin-like protein that
localizes to the shmoo tip (mating projection); mutants
are defective for mating projection formation, thereby
implicating Hbt1p in polarized cell morphogenesis"
/codon_start=1
/product="Hbt1p"
/protein_id="NP_010058.1"
/db_xref="GI:6319978"
/db_xref="SGD:S000002382"
/db_xref="GeneID:851303"
/translation="MNMNESISKDGQGEEEQNNFSFGGKPGSYDSNSDSAQRKKSFST
TKPTEYNLPKEQPESTSKNLETKAKNILLPWRKKHNKDSETPHEDTEADANRRANVTS
DVNPVSADTKSSSGPNATITTHGYSYVKTTTPAATSEQSKVKTSPPTSHEHSNIKASP
TAHRHSKGDAGHPSIATTHNHSTSKAATSPVTHTHGHSSATTSPVTHTHGHASVKTTS
PTNTHEHSKANTGPSATATTHGHINVKTTHPVSHGHSGSSTGPKSTAAAQDHSSTKTN
PSVTHGHTSVKDNSSATKGYSNTDSNSDRDVIPGSFRGMTGTDVNPVDPSVYTSTGPK
SNVSSGMNAVDPSVYTDTSSKSADRRKYSGNTATGPPQDTIKEIAQNVKMDESEQTGL
KNDQVSGSDAIQQQTMEPEPKAAVGTSGFVSQQPSYHDSNKNIQHPEKNKVDNKNISE
RAAEKFNIERDDILESADDYQQKNIKSKTDSNWGPIEYSSSAGKNKNLQDVVIPSSMK
EKFDSGTSGSQNMPKAGTELGHMKYNDNGRDNLQYVAGSQAGSQNTNNNIDMSPRHEA
EWSGLSNDATTRNNVVSPAMKDEDMNEDSTKPHQYGLDYLDDVEDYHENDIDDYSNAK
KNDLYSKKAYQGKPSDYNYEQREKIPGTFEPDTLSKSVQKQDEDPLSPRQTTNRAGME
TARDESLGNYEYSNTSGNKKLSDLSKNKSGPTPTRSNFIDQIEPRRAKTTQDIASDAK
DFTNNPETGTTGNVDTTGRMGAKSKTFSSNPFDDSKNTDTHLENANVAAFDNSRSGDT
TYSKSGDAETAAYDNIKNADPTYAKSQDITGMTHDQEPSSEQKASYGSGGNSQNQEYS
SDDNIDVNKNAKVLEEDAPGYKREVDLKNKRRTDLGGADASNAYAAEVGNFPSLIDPH
VPTYGFKDTNTSSSQKPSEGTYPETTSYSIHNETTSQGRKVSVGSMGSGKSKHHHNHH
RHSRQNSSKGSDYDYNNSTHSAEHTPRHHQYGSDEGEQDYHDDEQGEEQAGKQSFMGR
VRKSISGGTFGFRSEI"
gene complement(60872..61801)
/gene="FMP45"
/locus_tag="YDL222C"
/db_xref="GeneID:851304"
mRNA complement(60872..61801)
/gene="FMP45"
/locus_tag="YDL222C"
/product="Fmp45p"
/transcript_id="NM_001180282.1"
/db_xref="GI:296143151"
/db_xref="GeneID:851304"
CDS complement(60872..61801)
/gene="FMP45"
/locus_tag="YDL222C"
/note="Integral membrane protein localized to mitochondria
(untagged protein); required for sporulation and
maintaining sphingolipid content; has sequence similarity
to SUR7 and YNL194C"
/codon_start=1
/product="Fmp45p"
/protein_id="NP_010059.1"
/db_xref="GI:6319979"
/db_xref="SGD:S000002381"
/db_xref="GeneID:851304"
/translation="MIFKRFVNLLVFLFLLGAGLLTFFLILSGGRESGTLKNFYWLQA
DTNGFNSAPSTTRWYNYNWCGYEDGQLANCSSRAPAKPFSPRDNFGNSVNLPSSFRNN
RDTYYYLSRVGWAMLLISLFFIVLALVPGFLATFLPFKAVPVLYCVLSWLAFFFIILA
ACLYTGCYVKARKTFRNSGRSARLGPKNFAFIWTSVFLMLVNAIWSTIFSATHKAHST
YSDHDMYAQYESPSVDTGAQMEKSTYNSGATDGAGPITAAPVVGQPQPTTTTTPAGNG
KFFQKLKTRKQVPSAELEPAGDGGLAGPVTVRD"
gene complement(62244..65018)
/gene="CDC13"
/locus_tag="YDL220C"
/gene_synonym="EST4"
/db_xref="GeneID:851306"
mRNA complement(62244..65018)
/gene="CDC13"
/locus_tag="YDL220C"
/gene_synonym="EST4"
/product="Cdc13p"
/transcript_id="NM_001180280.1"
/db_xref="GI:296143152"
/db_xref="GeneID:851306"
CDS complement(62244..65018)
/gene="CDC13"
/locus_tag="YDL220C"
/gene_synonym="EST4"
/note="Single stranded DNA-binding protein found at TG1-3
telomere G-tails; regulates telomere replication through
recruitment of specific sub-complexes, but the essential
function is telomere capping; autophagy and proteasome are
involved in Cdc13p degradation"
/codon_start=1
/product="Cdc13p"
/protein_id="NP_010061.1"
/db_xref="GI:6319981"
/db_xref="SGD:S000002379"
/db_xref="GeneID:851306"
/translation="MDTLEEPECPPHKNRIFVSSSKDFEGYPSKAIVPVQFVALLTSI
HLTETKCLLGFSNFERRGDQSQEDQYLIKLKFKDRGSERLARITISLLCQYFDIELPD
LDSDSGASPTVILRDIHLERLCFSSCKALYVSKHGNYTLFLEDIKPLDLVSVISTIST
KSTNSSKHSSSELISECDLNNSLVDIFNNLIEMNRDEKNRFKFVKLIHYDIELKKFVQ
DQQKVLSQKSKAAAINPFFVPNRLGIPYIESQNEFNSQLMTLNVDEPTTDISNMGEEM
HDSADPIEDSDSSTTSSTGKYFSSKSYIQSQTPERKTSVPNNWHDDDSGSKRKRKLSF
HSPNASSIRKAISYEQLSLASVGSVERLEGKIVGMNPPQFASINEFKYCTLKLYFTQL
LPNVPDKVLVPGVNCIEIVIPTRERICELFGVLNCQSDKISDILLLEKPDRISVEVER
ILWDNDKTASPGMAVWSLKNISTDTQAQAQVQVPAQSSASIDPSRTRMSKMARKDPTI
EFCQLGLDTFETKYITMFGMLVSCSFDKPAFISFVFSDFTKNDIVQNYLYDRYLIDYE
NKLELNEGFKAIMYKNQFETFDSKLRKIFNNGLRDLQNGRDENLSQYGIVCKMNIKVK
MYNGKLNAIVRECEPVPHSQISSIASPSQCEHLRLFYQRAFKRIGESAISRYFEEYRR
FFPIHRNGSHLAKLRFDEVKHEPKKSPTTPALAEHIPDLNADVSSFDVKFTDISSLLD
SSARLPRPQQTHKSNTLYSCEGRIIAIEYHASDLCFHITNELPLLQTRGLAPERVLQL
HIITSKNFAYFFNRSSAYLQRQPLEEKYTQLAQFLGHSFKFNITSSLTLFPDTTVALQ
IWCPIECTFRELQQQLAHPKVAAAPDSGSLDCAINATVNPLRLLAAQNGVTVKKEEDN
DDDAGAVPTS"
gene 65242..65765
/gene="DTD1"
/locus_tag="YDL219W"
/db_xref="GeneID:851307"
mRNA join(65242..65306,65378..65765)
/gene="DTD1"
/locus_tag="YDL219W"
/product="Dtd1p"
/transcript_id="NM_001180279.1"
/db_xref="GI:296143153"
/db_xref="GeneID:851307"
CDS join(65242..65306,65378..65765)
/gene="DTD1"
/locus_tag="YDL219W"
/EC_number="3.1.-.-"
/note="D-Tyr-tRNA(Tyr) deacylase, functions in protein
translation, may affect nonsense suppression via
alteration of the protein synthesis machinery; ubiquitous
among eukaryotes"
/codon_start=1
/product="Dtd1p"
/protein_id="NP_010062.1"
/db_xref="GI:6319982"
/db_xref="SGD:S000002378"
/db_xref="GeneID:851307"
/translation="MKIVLQKVSQASVVVDSKVISSIKHGYMLLVGISIDDSMAEIDK
LSKKVLSLRIFEDESRNLWKKNIKEANGEILSVSQFTLMAKTKKGTKPDFHLAQKGHI
AKELYEEFLKLLRSDLGEEKVKDGEFGAMMSCSLTNEGPVTIILDSDQ"
gene 66493..67446
/locus_tag="YDL218W"
/db_xref="GeneID:851308"
mRNA 66493..67446
/locus_tag="YDL218W"
/product="hypothetical protein"
/transcript_id="NM_001180278.1"
/db_xref="GI:296143154"
/db_xref="GeneID:851308"
CDS 66493..67446
/locus_tag="YDL218W"
/note="hypothetical protein; YDL218W transcription is
regulated by Azf1p and induced by starvation and aerobic
conditions; expression also induced in cells treated with
the mycotoxin patulin"
/codon_start=1
/product="hypothetical protein"
/protein_id="NP_010063.1"
/db_xref="GI:6319983"
/db_xref="SGD:S000002377"
/db_xref="GeneID:851308"
/translation="MKRVTGVFLTLLRFSQFASSVLVMSLLAYAIHAYGNRGNKKTNF
TLATGVISVFYLIALGILCLALPTLIYIGMYFCAELIVCMLWLAAFVVLAKAQGERSC
SNTNADGLYYNPYSGQYTADSHRRACNSSQAAIAFSGLCFVLFLISVILLGINVLTPI
RKRYQTQGMWRSGASMGTKLHRWSGLALSEPFEETAAYDNTNVRTGDVEAGAGDNAAY
TSEPNGDARYATNDPNGQYHTTTTNTRYTTTTADPKTRYTTNDRNPGSANVANSAVDQ
HAYSTDESGDRSYQEKVTEGAHSGAMSGSTAEPNRNVNQMP"
gene complement(67983..68606)
/gene="TIM22"
/locus_tag="YDL217C"
/db_xref="GeneID:851309"
mRNA complement(67983..68606)
/gene="TIM22"
/locus_tag="YDL217C"
/product="Tim22p"
/transcript_id="NM_001180277.1"
/db_xref="GI:296143155"
/db_xref="GeneID:851309"
CDS complement(67983..68606)
/gene="TIM22"
/locus_tag="YDL217C"
/note="Essential core component of the mitochondrial TIM22
complex involved in insertion of polytopic proteins into
the inner membrane; forms the channel through which
proteins are imported"
/codon_start=1
/product="Tim22p"
/protein_id="NP_010064.1"
/db_xref="GI:6319984"
/db_xref="SGD:S000002376"
/db_xref="GeneID:851309"
/translation="MVYTGFGLEQISPAQKKPYNELTPEEQGERGAEMIMNFMTSCPG
KSVVSGVTGFALGGVLGLFMASMAYDTPLHTPTPANTAATATAGNIGVGGISRTVQQI
SDLPFRQQMKLQFTDMGKKSYSSAKNFGYIGMIYAGVECVIESLRAKNDIYNGVTAGF
FTGAGLAYKAGPQAALMGGAGFAAFSAAIDLYMKSEDGRPPQNDFKE"
gene complement(68997..70319)
/gene="RRI1"
/locus_tag="YDL216C"
/gene_synonym="CSN5; JAB1"
/db_xref="GeneID:851310"
mRNA complement(68997..70319)
/gene="RRI1"
/locus_tag="YDL216C"
/gene_synonym="CSN5; JAB1"
/product="Rri1p"
/transcript_id="NM_001180276.1"
/db_xref="GI:296143156"
/db_xref="GeneID:851310"
CDS complement(68997..70319)
/gene="RRI1"
/locus_tag="YDL216C"
/gene_synonym="CSN5; JAB1"
/EC_number="3.4.-.-"
/note="Catalytic subunit of the COP9 signalosome (CSN)
complex that acts as an isopeptidase in cleaving the
ubiquitin-like protein Nedd8 from SCF ubiquitin ligases;
metalloendopeptidase involved in the adaptation to
pheromone signaling"
/codon_start=1
/product="Rri1p"
/protein_id="NP_010065.2"
/db_xref="GI:93117369"
/db_xref="SGD:S000002375"
/db_xref="GeneID:851310"
/translation="MSLSNKTVKELRQLLKERYTVEDELTESIALSSMRFKPSQEPEF
HALSQSSLLKTKLKQQSSTDIPSYTHVLISKLSCEKITHYAVRGGNIEIMGILMGFTL
KDNIVVMDCFNLPVVGTETRVNAQLESYEYMVQYIDEMYNHNDGGDGRDYKGAKLNVV
GWFHSHPGYDCWLSNIDIQTQDLNQRFQDPYVAIVVDPLKSLEDKILRMGAFRTIESK
SDDNSATSYYELETIIFDSELNRALFETKLNLHCVIEDDESEQISLNRLIDSMKQYSY
LMDSKNVRTRIKLATTSERVSNENKKNIDYQNRSTRSQFCLNTQRGDSTETSSFGSMF
SGDNTSDVDMEDRNLTEFDSTDTSLCINGEPSIHVNRVERSSRSTDNFHNSKKRMNSN
QERCHDEGNDMLQRNVLETDYARAKNRILASKIKQYERLRFYKDTFTL"
gene complement(70640..73918)
/gene="GDH2"
/locus_tag="YDL215C"
/db_xref="GeneID:851311"
mRNA complement(70640..73918)
/gene="GDH2"
/locus_tag="YDL215C"
/product="glutamate dehydrogenase (NAD(+))"
/transcript_id="NM_001180275.1"
/db_xref="GI:296143157"
/db_xref="GeneID:851311"
CDS complement(70640..73918)
/gene="GDH2"
/locus_tag="YDL215C"
/EC_number="1.4.1.2"
/note="NAD(+)-dependent glutamate dehydrogenase, degrades
glutamate to ammonia and alpha-ketoglutarate; expression
sensitive to nitrogen catabolite repression and
intracellular ammonia levels"
/codon_start=1
/product="glutamate dehydrogenase (NAD(+))"
/protein_id="NP_010066.1"
/db_xref="GI:6319986"
/db_xref="SGD:S000002374"
/db_xref="GeneID:851311"
/translation="MLFDNKNRGALNSLNTPDIASLSISSMSDYHVFDFPGKDLQREE
VIDLLDQQGFIPDDLIEQEVDWFYNSLGIDDLFFSRESPQLISNIIHSLYASKLDFFA
KSKFNGIQPRLFSIKNKIITNDNHAIFMESNTGVSISDSQQKNFKFASDAVGNDTLEH
GKDTIKKNRIEMDDSCPPYELDSEIDDLFLDNKSQKNCRLVSFWAPESELKLTFVYES
VYPNDDPAGVDISSQDLLKGDIESISDKTMYKVSSNENKKLYGLLLKLVKEREGPVIK
TTRSVENKDEIRLLVAYKRFTTKRYYSALNSLFHYYKLKPSKFYLESFNVKDDDIIIF
SVYLNENQQLEDVLLHDVEAALKQVEREASLLYAIPNNSFHEVYQRRQFSPKEAIYAH
IGAIFINHFVNRLGSDYQNLLSQITIKRNDTTLLEIVENLKRKLRNETLTQQTIINIM
SKHYTIISKLYKNFAQIHYYHNSTKDMEKTLSFQRLEKVEPFKNDQEFEAYLNKFIPN
DSPDLLILKTLNIFNKSILKTNFFITRKVAISFRLDPSLVMTKFEYPETPYGIFFVVG
NTFKGFHIRFRDIARGGIRIVCSRNQDIYDLNSKNVIDENYQLASTQQRKNKDIPEGG
SKGVILLNPGLVEHDQTFVAFSQYVDAMIDILINDPLKENYVNLLPKEEILFFGPDEG
TAGFVDWATNHARVRNCPWWKSFLTGKSPSLGGIPHDEYGMTSLGVRAYVNKIYETLN
LTNSTVYKFQTGGPDGDLGSNEILLSSPNECYLAILDGSGVLCDPKGLDKDELCRLAH
ERKMISDFDTSKLSNNGFFVSVDAMDIMLPNGTIVANGTTFRNTFHTQIFKFVDHVDI
FVPCGGRPNSITLNNLHYFVDEKTGKCKIPYIVEGANLFITQPAKNALEEHGCILFKD
ASANKGGVTSSSMEVLASLALNDNDFVHKFIGDVSGERSALYKSYVVEVQSRIQKNAE
LEFGQLWNLNQLNGTHISEISNQLSFTINKLNDDLVASQELWLNDLKLRNYLLLDKII
PKILIDVAGPQSVLENIPESYLKVLLSSYLSSTFVYQNGIDVNIGKFLEFIGGLKREA
EASA"
gene complement(74446..76545)
/gene="PRR2"
/locus_tag="YDL214C"
/db_xref="GeneID:851312"
mRNA complement(74446..76545)
/gene="PRR2"
/locus_tag="YDL214C"
/product="Prr2p"
/transcript_id="NM_001180274.1"
/db_xref="GI:296143158"
/db_xref="GeneID:851312"
CDS complement(74446..76545)
/gene="PRR2"
/locus_tag="YDL214C"
/EC_number="2.7.11.1"
/note="Serine/threonine protein kinase that inhibits
pheromone induced signalling downstream of MAPK, possibly
at the level of the Ste12p transcription factor; mutant
has increased aneuploidy tolerance"
/codon_start=1
/product="Prr2p"
/protein_id="NP_010067.1"
/db_xref="GI:6319987"
/db_xref="SGD:S000002373"
/db_xref="GeneID:851312"
/translation="MSLSRILRYNQRNNKTTASLTAEHAYSDNWAYSVSLGDPTSVGV
NMAAKTGEALNKSYDSVFSSLPVADSVPRTDFTASSRDDENTDVQKLTTSWMEKIDTK
MPENISKIDSNIISSPMVSKVEARFIVPKGRLRKNSTDFTSSFSNSLSLPKSYGKLIF
FTSKKNSSSTKKNLANDISDNKHNNNSSNTIGHNIPVTTATATCDEIACTSTEHEYNV
YEEERMFTTRVYSLEDSVSSLSTNPLDDTYSEAVQVNTRHIEDTESTAHIRKHSYTTS
LSSIKRLFKITSFSNNNSNSCDHQESTVADDCAISSSLKETTSSPVSTGSFSLMIENE
DSDRDQIIQALYSNIEASTDLVSRKYRDLDVVLGEGSGGKVKLVQRVLDNKVFALKEY
RSKKKRESERKYIKNIISEYCIASTLKNPNICETLEILYEKGKIFQILEYCEYDLFSL
VMSEKMHYEEICCLFKQLINGVKYLHDIGLSHRDLKLDNCVVTRRGILKLIDFGASSV
FHYPLSSQMIEANGIVGSDPYLSPEVFYFNEYDPRALDVWSVGIIFFCMITRRFPWKY
PKVKDVQFKAFCSGRGVSSFKDLVTRPATDDSNNYDNDGYEEGVIDMGPNFILHRLPE
ETHKIMRRILEVSPFRRITINGILQDGWIKEIETCQVVGAASPNEASLRIINKGNHIH
TNIDQRYAHIGGLHQRT"
gene complement(77289..77966)
/gene="NOP6"
/locus_tag="YDL213C"
/db_xref="GeneID:851313"
mRNA complement(77289..77966)
/gene="NOP6"
/locus_tag="YDL213C"
/product="Nop6p"
/transcript_id="NM_001180273.1"
/db_xref="GI:296143159"
/db_xref="GeneID:851313"
CDS complement(77289..77966)
/gene="NOP6"
/locus_tag="YDL213C"
/note="rRNA-binding protein required for 40S ribosomal
subunit biogenesis; contains an RNA recognition motif
(RRM); hydrophilin essential to overcome the stress of the
desiccation-rehydration process; NOP6 may be a
fungal-specific gene as no homologs have been yet
identified in higher eukaryotes"
/codon_start=1
/product="Nop6p"
/protein_id="NP_010068.1"
/db_xref="GI:6319988"
/db_xref="SGD:S000002372"
/db_xref="GeneID:851313"
/translation="MGSEEDKKLTKKQLKAQQFRKSKEEKDQEKDVKKEQAPEGKRPN
SAAGNDGEEPVKKKRKTRRGRGGKGKNGKKGNRFIVFVGSLPRDITAVELQNHFKNSS
PDQIRLRADKGIAFLEFDADKDRTGIQRRMDIALLQHGTLLKEKKINVELTVGGGGNS
QERLEKLKNKNIKLDEERKERLTKMINDGNQKKIAKTTATAAQTSGTDNKPVPAGIHP
DRAKLLK"
gene 78426..79058
/gene="SHR3"
/locus_tag="YDL212W"
/gene_synonym="APF1"
/db_xref="GeneID:851314"
mRNA 78426..79058
/gene="SHR3"
/locus_tag="YDL212W"
/gene_synonym="APF1"
/product="Shr3p"
/transcript_id="NM_001180272.1"
/db_xref="GI:296143160"
/db_xref="GeneID:851314"
CDS 78426..79058
/gene="SHR3"
/locus_tag="YDL212W"
/gene_synonym="APF1"
/note="Endoplasmic reticulum packaging chaperone, required
for incorporation of amino acid permeases into COPII
coated vesicles for transport to the cell surface"
/codon_start=1
/product="Shr3p"
/protein_id="NP_010069.1"
/db_xref="GI:6319989"
/db_xref="SGD:S000002371"
/db_xref="GeneID:851314"
/translation="MFSYSDFCSIGTAMILSATTFLMGVFFSNMPYDYHLLFNPNSTQ
EHFDLALRHYQILHETPLPVIVTLCVVAGIGLVGGTIKVFKPNPELQMFEYCSLGLYV
LAICVFLTNVKTGIDCSVSHNWGEVTENQGLAVIASSNIILLVMFAGVIILQIGLWYS
NWDLQKRLKEFYAQEEREAANAGKKTEKVDNAKKNDNKSKGAQKRKNAKK"
gene complement(79294..80412)
/locus_tag="YDL211C"
/db_xref="GeneID:851315"
mRNA complement(79294..80412)
/locus_tag="YDL211C"
/product="hypothetical protein"
/transcript_id="NM_001180271.1"
/db_xref="GI:296143161"
/db_xref="GeneID:851315"
CDS complement(79294..80412)
/locus_tag="YDL211C"
/note="hypothetical protein; green fluorescent protein
(GFP)-fusion protein localizes to the vacuole"
/codon_start=1
/product="hypothetical protein"
/protein_id="NP_010070.1"
/db_xref="GI:6319990"
/db_xref="SGD:S000002370"
/db_xref="GeneID:851315"
/translation="MLLNVTSSQYISTPQSRSLSEIDTSETASLSSATDHIFALSTEV
VSSITTNLIEGLESSIQVPISTAYGTTSFRNNTSSPQYLVSNCTSSVQSNITIDRGLL
STLKTFTTSQVPTIEPSTTKLTTPLSTTFTSTSTSEIYSVFTSENSVYIIYDQEYKFT
ERSTTFNTHFPQTTVLQESNPPLTFTIPSNTITGDAKLYQYLSGALNTQDTSDANNRR
TGVIVGSTVGVVIGVVIVIFIGFIIIRNRRNVKNHSKKGFSHDIGKRVSCDEVTETEA
PSNPFLNVLNYKVTTNGEGKRDSFENGRDLHRASSSDGIYIAHPYYGMADHESGRFSY
VSSYNESAESSIEETSSSASTITRPNIQQTNSFLREII"
gene 83548..83618
/locus_tag="tG(GCC)D1"
/db_xref="GeneID:851316"
tRNA 83548..83618
/locus_tag="tG(GCC)D1"
/product="tRNA-Gly"
/note="Glycine tRNA (tRNA-Gly), predicted by tRNAscan-SE
analysis"
/db_xref="SGD:S000006576"
/db_xref="GeneID:851316"
gene 84270..85985
/gene="UGA4"
/locus_tag="YDL210W"
/db_xref="GeneID:851317"
mRNA 84270..85985
/gene="UGA4"
/locus_tag="YDL210W"
/product="Uga4p"
/transcript_id="NM_001180270.1"
/db_xref="GI:296143162"
/db_xref="GeneID:851317"
CDS 84270..85985
/gene="UGA4"
/locus_tag="YDL210W"
/note="Permease that serves as a gamma-aminobutyrate
(GABA) transport protein involved in the utilization of
GABA as a nitrogen source; catalyzes the transport of
putrescine and delta-aminolevulinic acid (ALA); localized
to the vacuolar membrane"
/codon_start=1
/product="Uga4p"
/protein_id="NP_010071.1"
/db_xref="GI:6319991"
/db_xref="SGD:S000002369"
/db_xref="GeneID:851317"
/translation="MSMSSKNENKISVEQRISTDIGQAYQLQGLGSNLRSIRSKTGAG
EVNYIDAAKSVNDNQLLAEIGYKQELKRQFSTLQVFGIAFSIMGLLPSIASVMGGGLG
GGPATLVWGWFVAAFFILLVGITMAEHASSIPTAGGLYYWTYYYAPEGYKEIISFIIG
CSNSLALAAGVCSIDYGLAEEIAAAVTLTKDGNFEVTSGKLYGIFAGAVVVMCICTCV
ASGAIARLQTLSIFANLFIIVLLFIALPIGTKHRMGGFNDGDFIFGKYENLSDWNNGW
QFCLAGFMPAVWTIGSFDSCVHQSEEAKDAKKSVPIGIISSIAVCWILGWLIIICLMA
CINPDIDSVLDSKYGFALAQIIYDSLGKKWAIAFMSLIAFCQFLMGASITTAVSRQVW
AFSRDNGLPLSKYIKRVDSKYSVPFFAILAACVGSLILGLLCLIDDAATDALFSLAVA
GNNLAWSTPTVFRLTSGRDLFRPGPFYLGKIWSPIVAWTGVAFQLFIIILVMFPSQQH
GITKSTMNYACVIGPGIWILAGIYYKVYKKKYYHGPATNLSDDDYTEAVGADVIDTIM
SKQEP"
rep_origin 85945..86176
/note="ARS405;
Autonomously Replicating Sequence"
/db_xref="SGD:S000118428"
gene complement(86207..87226)
/gene="CWC2"
/locus_tag="YDL209C"
/gene_synonym="NTC40"
/db_xref="GeneID:851318"
mRNA complement(86207..87226)
/gene="CWC2"
/locus_tag="YDL209C"
/gene_synonym="NTC40"
/product="Cwc2p"
/transcript_id="NM_001180269.1"
/db_xref="GI:296143163"
/db_xref="GeneID:851318"
CDS complement(86207..87226)
/gene="CWC2"
/locus_tag="YDL209C"
/gene_synonym="NTC40"
/note="Member of the NineTeen Complex (NTC) that contains
Prp19p and stabilizes U6 snRNA in catalytic forms of the
spliceosome containing U2, U5, and U6 snRNAs; binds
directly to U6 snRNA; similar to S. pombe Cwf2"
/codon_start=1
/product="Cwc2p"
/protein_id="NP_010072.1"
/db_xref="GI:6319992"
/db_xref="SGD:S000002368"
/db_xref="GeneID:851318"
/translation="MTSWRDKSAKVQVKESELPSSIPAQTGLTFNIWYNKWSQGFAGN
TRFVSPFALQPQLHSGKTRGDNDGQLFFCLFFAKGMCCLGPKCEYLHHIPDEEDIGKL
ALRTEVLDCFGREKFADYREDMGGIGSFRKKNKTLYVGGIDGALNSKHLKPAQIESRI
RFVFSRLGDIDRIRYVESKNCGFVKFKYQANAEFAKEAMSNQTLLLPSDKEWDDRREG
TGLLVKWANEDPDPAAQKRLQEELKLESLNMMVHLINNNTNSAGTEVNNKNNERLDRT
FPEASVDNVKKRLLPLDNGMESDDFIEKLKKVKKNISRENISSKPSVGKLGGPLLDYL
SSDED"
gene 87512..87982
/gene="NHP2"
/locus_tag="YDL208W"
/db_xref="GeneID:851319"
mRNA 87512..87982
/gene="NHP2"
/locus_tag="YDL208W"
/product="Nhp2p"
/transcript_id="NM_001180268.1"
/db_xref="GI:296143164"
/db_xref="GeneID:851319"
CDS 87512..87982
/gene="NHP2"
/locus_tag="YDL208W"
/note="Nuclear protein related to mammalian high mobility
group (HMG) proteins, essential for function of H/ACA-type
snoRNPs, which are involved in 18S rRNA processing"
/codon_start=1
/product="Nhp2p"
/protein_id="NP_010073.2"
/db_xref="GI:82795243"
/db_xref="SGD:S000002367"
/db_xref="GeneID:851319"
/translation="MGKDNKEHKESKESKTVDNYEARMPAVLPFAKPLASKKLNKKVL
KTVKKASKAKNVKRGVKEVVKALRKGEKGLVVIAGDISPADVISHIPVLCEDHSVPYI
FIPSKQDLGAAGATKRPTSVVFIVPGSNKKKDGKNKEEEYKESFNEVVKEVQAL"
gene 88248..89864
/gene="GLE1"
/locus_tag="YDL207W"
/gene_synonym="BRR3; RSS1"
/db_xref="GeneID:851320"
mRNA 88248..89864
/gene="GLE1"
/locus_tag="YDL207W"
/gene_synonym="BRR3; RSS1"
/product="Gle1p"
/transcript_id="NM_001180267.1"
/db_xref="GI:296143165"
/db_xref="GeneID:851320"
CDS 88248..89864
/gene="GLE1"
/locus_tag="YDL207W"
/gene_synonym="BRR3; RSS1"
/note="Cytoplasmic nucleoporin required for polyadenylated
RNA export; not essential for protein import; contains a
nuclear export signal; when bound to inositol
hexakisphosphate (IP6), functions as an activator for the
Dbp5p ATPase activity at the nuclear pore complex during
mRNA export"
/codon_start=1
/product="Gle1p"
/protein_id="NP_010074.1"
/db_xref="GI:6319994"
/db_xref="SGD:S000002366"
/db_xref="GeneID:851320"
/translation="MRFVFDEVFNSDTDSPEFEETCSTTSSTSSQCPTPEPSPAIKLP
SFTKVGTKKLVNESVVILDPALENALRDLNLQSKLIPINEPIVAASSIIVPHSTNMPL
PRASHSSLLDNAKNSNATAPLLEAIEESFQRKMQNLVLANQKEIQSIRENKRRVEEQR
KRKEEEERKRKEAEEKAKREQELLRQKKDEEERKRKEAEAKLAQQKQEEERKKIEEQN
EKERQLKKEHEAKLLQQKDKLGKAVTNFDKISKMFWHYKDKIAQIKQDIVLPIKKADV
NVRNLLSRHKRKINPKFGQLTNSNQQLFKIQNELTQLINDTKGDSLAYHWILNFIAKA
VVHQAETEVRVKPESALPLGKLTLYLLVQFPELQELFMARLVKKCPFVIGFTCEIDTE
KGRQNMGWKRNNENKWEDNTSYDERMGGILSLFAIITRLQLPQEFITTTSHPFPIALS
WHILARICNTPLNLITNTHFVILGSWWDAAAVQFLQAYGNQASKLLILIGEELTSRMA
EKKYVGAARLRILLEAWQNNNMESFPEMSP"
gene 90176..92464
/locus_tag="YDL206W"
/db_xref="GeneID:851321"
mRNA 90176..92464
/locus_tag="YDL206W"
/product="hypothetical protein"
/transcript_id="NM_001180266.1"
/db_xref="GI:296143166"
/db_xref="GeneID:851321"
CDS 90176..92464
/locus_tag="YDL206W"
/note="hypothetical protein; YDL206W is not an essential
protein"
/codon_start=1
/product="hypothetical protein"
/protein_id="NP_010075.1"
/db_xref="GI:6319995"
/db_xref="SGD:S000002365"
/db_xref="GeneID:851321"
/translation="MHKPLRWLITIAFYVSNVILIGYSLSSNGSISEFYLHSVVLIEC
FSLLGVVTSDCLTPSLSYISSNIFHISDRVSGMTLLALGNALPDITSTYQSMKSGVTS
LAIGELFGGIFFLLTVVIGLMGCVATIQFQHDKSIETYTEESFDQNLSYDRSNYILDV
GIFTFMLLVSGTFLADGRLYFWECIVMVLTYCCCAVYLIKSYKYPCEINDALEREVEI
KKTVLANNHITVPNRFTLTTTSDITSTDDGIRYVRPLGDTQIDEDNAISLDPTRLPSK
SLDNISRFNQGIPERRDLIRRRIRGYLRSHYHGWVRMTLQDLLNIWEKQNLFNNTVKS
LSLPSDDTHLFTKASLDEEGRPLIRKRMNSLQPKDFYKYLSLRNGENSNALDTAISAP
QNEYQTYYNEPTSLFLTVPQKKTSKKSLSCDRIPNLVRSNNIILNDEATRTQESTNAL
NSISDVIDNSLLQYERDDIILDRTLSLCSTKSRTAWHSFQLYNYLTDVSLEIGFFEFL
SLLVTTPVSIILYLSIPSEISQTDHDLPLSYLQNIQLIASPIILNQLITNNFSFWLLI
LSLVIAILLYFKTRTIPNKFNSDIIFTVAFLLSLACLSKAVHIIVVTLTHWINVFNIS
ETILGLTIFTWGNSIGDLVSNITFVKIGVLEIAIGACFGSPLLYFLFGVGFDGIMIML
GDKTGKIVSGRDSNILMHHIDFKVDKNLINTGVGILIAFLIFTVLIPLNDWKIDKKIS
IALLTLYIVVTCISVFLEVHQV"
gene complement(92762..93745)
/gene="HEM3"
/locus_tag="YDL205C"
/gene_synonym="OLE2"
/db_xref="GeneID:851322"
mRNA complement(92762..93745)
/gene="HEM3"
/locus_tag="YDL205C"
/gene_synonym="OLE2"
/product="hydroxymethylbilane synthase"
/transcript_id="NM_001180265.1"
/db_xref="GI:296143167"
/db_xref="GeneID:851322"
CDS complement(92762..93745)
/gene="HEM3"
/locus_tag="YDL205C"
/gene_synonym="OLE2"
/EC_number="2.5.1.61"
/note="Porphobilinogen deaminase, catalyzes the conversion
of 4-porphobilinogen to hydroxymethylbilane, the third
step in heme biosynthesis; localizes to the cytoplasm and
nucleus; expression is regulated by Hap2p-Hap3p, but not
by levels of heme"
/codon_start=1
/product="hydroxymethylbilane synthase"
/protein_id="NP_010076.1"
/db_xref="GI:6319996"
/db_xref="SGD:S000002364"
/db_xref="GeneID:851322"
/translation="MGPETLHIGGRKSKLAVIQSNHVLKLIEEKYPDYDCKVFTLQTL
GDQIQFKPLYSFGGKALWTKELEDHLYHDDPSKKLDLIVHSLKDMPTLLPEGFELGGI
TKRVDPTDCLVMPFYSAYKSLDDLPDGGIVGTSSVRRSAQLKRKYPHLKFESVRGNIQ
TRLQKLDDPKSPYQCIILASAGLMRMGLENRITQRFHSDTMYHAVGQGALGIEIRKGD
TKMMKILDEICDLNATICCLSERALMRTLEGGCSVPIGVESKYNEETKKLLLKAIVVD
VEGTEAVEDEIEMLIENVKEDSMACGKILAERMIADGAKKILDEINLDRIK"
gene 94605..95786
/gene="RTN2"
/locus_tag="YDL204W"
/db_xref="GeneID:851323"
mRNA 94605..95786
/gene="RTN2"
/locus_tag="YDL204W"
/product="Rtn2p"
/transcript_id="NM_001180264.1"
/db_xref="GI:296143168"
/db_xref="GeneID:851323"
CDS 94605..95786
/gene="RTN2"
/locus_tag="YDL204W"
/note="Reticulon protein that stabilizes membrane
curvature; interacts with Rtn1p, Yop1p, and Sey1p to
maintain tubular ER morphology; involved in nuclear pore
assembly; interacts with exocyst subunit Sec6p, with
Yip3p, and with Sbh1p; similar to and much less abundant
than Rtn1p; rtn1 rtn2 yop1 triple mutant lacks tubular ER;
member of the RTNLA (reticulon-like A) subfamily; protein
increases in abundance and relocalizes to the plasma
membrane upon DNA replication stress"
/codon_start=1
/product="Rtn2p"
/protein_id="NP_010077.1"
/db_xref="GI:6319997"
/db_xref="SGD:S000002363"
/db_xref="GeneID:851323"
/translation="MNRNTTTNKNANLNNSRNANAPGEAGHQNKTGLIYWTNPSKSGA
SFAATLVSLLILRNVNVISVLLKIGYMVLFTSFAVELSTKVLFDKGVVSRFGMQESPD
LVGVLKPHIDRELDRLPALEDRIRKLVFAHRTRNNFTIGVSLYFLHGLFAIFSMNTVL
IMTTIFLYTVPLIYDRKQARIDRAIDRMKDLVIHRFHKNYNKVVEKTEPYIDKIIPPQ
TDEGSYSTSISNENKSSTSQRNKSGLSSSEFDNMNDTSASKSGKDSYSTSQYNRAEYP
VSQNENIGTLKSGKQEIPTEKDFNNRHENFSKPDVKTYDPRTVDIEEELAAHQRELEQ
NLKDGDYNLVGSKEIPDPITVPAPTRHTTKPAESQSIPIKNNETLHKTTHGLKQKLQH
A"
gene complement(96082..97953)
/gene="ACK1"
/locus_tag="YDL203C"
/db_xref="GeneID:851324"
mRNA complement(96082..97953)
/gene="ACK1"
/locus_tag="YDL203C"
/product="Ack1p"
/transcript_id="NM_001180263.1"
/db_xref="GI:296143169"
/db_xref="GeneID:851324"
CDS complement(96082..97953)
/gene="ACK1"
/locus_tag="YDL203C"
/note="Protein that functions upstream of Pkc1p in the
cell wall integrity pathway; GFP-fusion protein expression
is induced in response to the DNA-damaging agent MMS;
non-tagged Ack1p is detected in purified mitochondria"
/codon_start=1
/product="Ack1p"
/protein_id="NP_010078.1"
/db_xref="GI:6319998"
/db_xref="SGD:S000002362"
/db_xref="GeneID:851324"
/translation="MVNQGQPQPNLYDKHINMFPPARARESSHKLGNANSDRHGLPAQ
NIVPAPYPVDDSIVELTPAIPFTSPSSSSSLSLPLSALNFTDGNADGGQLGTPVTINS
NNGMDIFNSKPTGEIGYANNGTNSTGSRYELPFNFSSTKESLGSPAVQDASISSGNRI
SESVRDNSAPPPYEESESRILQEKVYRTEEKAPIRPLNNNPVPPQKINQPPTGSAKTD
DNGSSGGEDKLSSYSPEALAFYQVYKKTITDSSKFTPEIQMQWCETLLTYAFNEDFIS
QYNINAEKLKRSLKPEEMLKNQKVILEHSFKVLTKLITLKWPPAMYLMGTLYSHQPYL
PIKNKNIVIKNDEKALEYYCKAAKLNNSDACYRAGVCFEYQRGTSSLDPSPTKEQCIK
KAFQYYQHGAEVCSNSACMYKLGMSHLYGLNMQKTDVLLAIKWFDKAAQKGDSPQTLY
ELGKIYEFSVLPPEIQNLLFANGIRKDSQLAIKYYQQCAKDFEYPLAQWKLGNCYEFG
DLGLPVVAKKSIYWYSKAAAAQPKGNPMAMLSLSGWYLTGAPNILKPNNKEAFNWALK
SSKCSDGKLARTEFALGFYYEKGVGCEVDLDLAKQYYQRAARMGFRKAVDALRSLTN"
gene 98475..99224
/gene="MRPL11"
/locus_tag="YDL202W"
/db_xref="GeneID:851325"
mRNA 98475..99224
/gene="MRPL11"
/locus_tag="YDL202W"
/product="mitochondrial 54S ribosomal protein YmL11"
/transcript_id="NM_001180262.1"
/db_xref="GI:296143170"
/db_xref="GeneID:851325"
CDS 98475..99224
/gene="MRPL11"
/locus_tag="YDL202W"
/note="Mitochondrial ribosomal protein of the large
subunit"
/codon_start=1
/product="mitochondrial 54S ribosomal protein YmL11"
/protein_id="NP_010079.1"
/db_xref="GI:6319999"
/db_xref="SGD:S000002361"
/db_xref="GeneID:851325"
/translation="MLQLRFMPGWVPRNGFFGLKETIGTVHKRFYALASEQPSRKTVK
PLDSRKTFLIDTYKHLMENSSMIFFVHYNNLSKTEDHHFRFKIKQTGGKLTKVRNNLF
EVYLRNSHLPDPCGFVKRKEQNWKHPLLPLLKGPTATITYEDTNPQQVAKLLKVLQSA
QDKLMVIGAKVENEVLNVEKINTFKTLPTKPEMQSQLVSVLQMLSGLGLVRTLENSSN
ALYLTLKSHNDNQKPKEDVESTTDAESKGSK"
gene 99561..100421
/gene="TRM8"
/locus_tag="YDL201W"
/db_xref="GeneID:851326"
mRNA 99561..100421
/gene="TRM8"
/locus_tag="YDL201W"
/product="Trm8p"
/transcript_id="NM_001180261.1"
/db_xref="GI:296143171"
/db_xref="GeneID:851326"
CDS 99561..100421
/gene="TRM8"
/locus_tag="YDL201W"
/EC_number="2.1.1.33"
/note="Noncatalytic subunit of a tRNA methyltransferase
complex; Trm8p and Trm82p comprise an enzyme that
catalyzes a methyl-transfer from S-adenosyl-l-methionine
to the N(7) atom of guanine at position 46 in tRNA; Trm8
lacks catalytic activity if not bound to Trm82p"
/codon_start=1
/product="Trm8p"
/protein_id="NP_010080.1"
/db_xref="GI:6320000"
/db_xref="SGD:S000002360"
/db_xref="GeneID:851326"
/translation="MKAKPLSQDPGSKRYAYRINKEENRKELKHVKINESSLVQEGQK
IDLPKKRYYRQRAHSNPFSDHQLEYPVSPQDMDWSKLYPYYKNAENGQMTKKVTIADI
GCGFGGLMIDLSPAFPEDLILGMEIRVQVTNYVEDRIIALRNNTASKHGFQNINVLRG
NAMKFLPNFFEKGQLSKMFFCFPDPHFKQRKHKARIITNTLLSEYAYVLKEGGVVYTI
TDVKDLHEWMVKHLEEHPLFERLSKEWEENDECVKIMRNATEEGKKVERKKGDKFVAC
FTRLPTPAIL"
gene complement(100501..101067)
/gene="MGT1"
/locus_tag="YDL200C"
/db_xref="GeneID:851327"
mRNA complement(100501..101067)
/gene="MGT1"
/locus_tag="YDL200C"
/product="Mgt1p"
/transcript_id="NM_001180260.1"
/db_xref="GI:296143172"
/db_xref="GeneID:851327"
CDS complement(100501..101067)
/gene="MGT1"
/locus_tag="YDL200C"
/EC_number="2.1.1.63"
/note="DNA repair methyltransferase (6-O-methylguanine-DNA
methylase) involved in protection against DNA alkylation
damage"
/codon_start=1
/product="Mgt1p"
/protein_id="NP_010081.2"
/db_xref="GI:93117370"
/db_xref="SGD:S000002359"
/db_xref="GeneID:851327"
/translation="MKELLYYTFIETEVTGAFLVFREKTQNLVFASLGNDKLFLLGKV
EGFLKKHEKQDTMYDLQELKEAETYKKSIENYTICLENKMPLPSGAIPFEFLFGTDFQ
RKVWNELLNVEHGHVVTYGDIAKRIGKPTAARSVGRACGSNNLALLVPCHRIVGSNRK
LTGYKWSCKLKEQLLNNEKENSLSLSRL"
gene complement(101290..103353)
/locus_tag="YDL199C"
/db_xref="GeneID:851328"
mRNA complement(101290..103353)
/locus_tag="YDL199C"
/product="hypothetical protein"
/transcript_id="NM_001180259.1"
/db_xref="GI:296143173"
/db_xref="GeneID:851328"
CDS complement(101290..103353)
/locus_tag="YDL199C"
/note="Putative transporter, member of the sugar porter
family"
/codon_start=1
/product="hypothetical protein"
/protein_id="NP_010082.1"
/db_xref="GI:6320002"
/db_xref="SGD:S000002358"
/db_xref="GeneID:851328"
/translation="MKPPLNMSRSNKPLTQEANSSAHIDRAHQLAQDFNSKQDDTALT
SLPHKNPDIFRFENNITAHSSRRGSLYRDSDATVVLPLSEHTPRLSMDDPYRQLLQQA
EISQLRSKKKRHSSRVLRTSFISFVVLVSSLSGLDQGLISGNVMTLSFQKYFHYPLTS
PLGNIVSIVNLGAFMASLFVYSGILEPCSRKKMLQISTMIYSLGAIVQVLALNQWCLL
LGRFLLGVGMGFAFSMVIIYQFEFPLPCIRKRTLISIQCVSSVIAYSFGIWINCAFRY
LGFAWRYPLSTHVALGIILNLMSFYLILESPSWLLKQKNDVEALVLISNVFDDGNFEE
NQTQLKFRVLKRDILLKSHLQKNSYPYAYILKDFSSIIKLLIGFQLLTRTNGVDAFLY
YSPLILQQMGRGERKSIYLTGLNALIYSIVILAYVPLVLRKRKEKTNVLLGSIVMCAL
LFTISFTDWFPKSTTRYISILFAVFLFTHFISWDSIGWVMTIELLPHLSQAPVILLVS
NFYWIFKWFVSLITPILIDRLSWKFYLIPSLSSFISIIFVLKIFPIETRDERLDSDDD
STGNGSGNHDDVFDDTGSEFSSSPSFSAYQINTLGSSIKQNNQAYSSIQNEQILPKNG
NLSNQTHGSAQNVYFITSDSGPSRTGEFFSFHNRTDPNISDNIAANKPSSGGGQNSPG
DMAVA"
gene complement(103649..104551)
/gene="GGC1"
/locus_tag="YDL198C"
/gene_synonym="YHM1"
/db_xref="GeneID:851329"
mRNA complement(103649..104551)
/gene="GGC1"
/locus_tag="YDL198C"
/gene_synonym="YHM1"
/product="Ggc1p"
/transcript_id="NM_001180258.1"
/db_xref="GI:296143174"
/db_xref="GeneID:851329"
CDS complement(103649..104551)
/gene="GGC1"
/locus_tag="YDL198C"
/gene_synonym="YHM1"
/note="Mitochondrial GTP/GDP transporter, essential for
mitochondrial genome maintenance; has a role in
mitochondrial iron transport; member of the mitochondrial
carrier family"
/codon_start=1
/product="Ggc1p"
/protein_id="NP_010083.1"
/db_xref="GI:6320003"
/db_xref="SGD:S000002357"
/db_xref="GeneID:851329"
/translation="MPHTDKKQSGLARLLGSASAGIMEIAVFHPVDTISKRLMSNHTK
ITSGQELNRVIFRDHFSEPLGKRLFTLFPGLGYAASYKVLQRVYKYGGQPFANEFLNK
HYKKDFDNLFGEKTGKAMRSAAAGSLIGIGEIVLLPLDVLKIKRQTNPESFKGRGFIK
ILRDEGLFNLYRGWGWTAARNAPGSFALFGGNAFAKEYILGLKDYSQATWSQNFISSI
VGACSSLIVSAPLDVIKTRIQNRNFDNPESGLRIVKNTLKNEGVTAFFKGLTPKLLTT
GPKLVFSFALAQSLIPRFDNLLSK"
gene complement(104917..106494)
/gene="ASF2"
/locus_tag="YDL197C"
/db_xref="GeneID:851330"
mRNA complement(104917..106494)
/gene="ASF2"
/locus_tag="YDL197C"
/product="Asf2p"
/transcript_id="NM_001180257.1"
/db_xref="GI:296143175"
/db_xref="GeneID:851330"
CDS complement(104917..106494)
/gene="ASF2"
/locus_tag="YDL197C"
/note="Anti-silencing protein that causes derepression of
silent loci when overexpressed"
/codon_start=1
/product="Asf2p"
/protein_id="NP_010084.1"
/db_xref="GI:6320004"
/db_xref="SGD:S000002356"
/db_xref="GeneID:851330"
/translation="MPKNRGVLDAITRSVIDGSDQESSSSFNSDKEYAAVTKGLSSSR
VQKKSSLRQMKSKVKELQSLVNHYRENEAALVSSAKLLSGEIIGYEIKMASLHGKMKS
ILDENNALKETHKSSAEKRIELVRLPSSKEERNYDEYTLLVNLKKEICAKLQDYKNVQ
NTVNTKLDEIHTFHEKYYEGLELSLDSKVFDAESSKELAKVRRELNNVRKNSEIKVNN
LKMQLLQATKSLEHLKKQAKAKDDYLKCIPELVDKANLTMLSYKKSIANQRETIEALQ
AELSQQSETKGQIETETQNQVQIPTNVTLVDPFEENNPEDLFAIQEQELQDLRLHKKM
ADERSRTTHLHLERKNNTIKLLQSYVQSLIQRLPPAQRKHHLGIFQKLGSEKSCPLAP
AVASTYAPLLLLSQHSNHQEIDNTPQRLLLAAPDGQSYSEKSTTLNLDYSSRKSYLSR
LQPPHIANLKSLTLKTLPRVPTDSPQLPSKDKSQETAKKDDRPKLVANEPVTLDTSTP
PVAQSLADSKHCSGLHK"
gene 107208..111029
/gene="SEC31"
/locus_tag="YDL195W"
/gene_synonym="WEB1"
/db_xref="GeneID:851332"
mRNA 107208..111029
/gene="SEC31"
/locus_tag="YDL195W"
/gene_synonym="WEB1"
/product="Sec31p"
/transcript_id="NM_001180255.2"
/db_xref="GI:330443496"
/db_xref="GeneID:851332"
CDS 107208..111029
/gene="SEC31"
/locus_tag="YDL195W"
/gene_synonym="WEB1"
/note="Component of the Sec13p-Sec31p complex of the COPII
vesicle coat, required for vesicle formation in ER to
Golgi transport; mutant has increased aneuploidy
tolerance"
/codon_start=1
/product="Sec31p"
/protein_id="NP_010086.2"
/db_xref="GI:330443497"
/db_xref="SGD:S000002354"
/db_xref="GeneID:851332"
/translation="MVKLAEFSRTATFAWSHDKIPLLVSGTVSGTVDANFSTDSSLEL
WSLLAADSEKPIASLQVDSKFNDLDWSHNNKIIAGALDNGSLELYSTNEANNAINSMA
RFSNHSSSVKTVKFNAKQDNVLASGGNNGEIFIWDMNKCTESPSNYTPLTPGQSMSSV
DEVISLAWNQSLAHVFASAGSSNFASIWDLKAKKEVIHLSYTSPNSGIKQQLSVVEWH
PKNSTRVATATGSDNDPSILIWDLRNANTPLQTLNQGHQKGILSLDWCHQDEHLLLSS
GRDNTVLLWNPESAEQLSQFPARGNWCFKTKFAPEAPDLFACASFDNKIEVQTLQNLT
NTLDEQETETKQQESETDFWNNVSREESKEKPTVFHLQAPTWYGEPSPAAHWAFGGKL
VQITPDGKGVSITNPKISGLESNTTLSEALKTKDFKPLINQRLVKVIDDVNEEDWNLL
EKLSMDGTEEFLKEALAFDNDESDAQDDANNEKEDDGEEFFQQIETNFQPEGDFSLSG
NIEQTISKNLVSGNIKSAVKNSLENDLLMEAMVIALDSNNERLKESVKNAYFAKYGSK
SSLSRILYSISKREVDDLVENLDVSQWKFISKAIQNLYPNDIAQRNEMLIKLGDRLKE
NGHRQDSLTLYLAAGSLDKVASIWLSEFPDLEDKLKKDNKTIYEAHSECLTEFIERFT
VFSNFINGSSTINNEQLIAKFLEFINLTTSTGNFELATEFLNSLPSDNEEVKTEKARV
LIASGKSLPAQNPATATTSKAKYTNAKTNKNVPVLPTPGMPSTTSIPSMQAPFYGMTP
GASANALPPKPYVPATTTSAPVHTEGKYAPPSQPSMASPFVNKTNSSTRLNSFAPPPN
PYATATVPATNVSTTSIPQNTFAPIQPGMPIMGDYNAQSSSIPSQPPINAVSGQTPHL
NRKANDGWNDLPLKVKEKPSRAKAVSVAPPNILSTPTPLNGIPANAASTMPPPPLSRA
PSSVSMVSPPPLHKNSRVPSLVATSESPRASISNPYAPPQSSQQFPIGTISTANQTSN
TAQVASSNPYAPPPQQRVATPLSGGVPPAPLPKASNPYAPTATTQPNGSSYPPTGPYT
NNHTMTSPPPVFNKPPTGPPPISMKKRSNKLASIEQNPSQGATYPPTLSSSASPLQPS
QPPTLASQVNTSAENVSHEIPADQQPIVDFLKEELARVTPLTPKEYSKQLKDCDKRLK
ILFYHLEKQDLLTQPTIDCLHDLVALMKEKKYKEAMVIHANIATNHAQEGGNWLTGVK
RLIGIAEATLN"
gene 111580..114234
/gene="SNF3"
/locus_tag="YDL194W"
/db_xref="GeneID:851333"
mRNA 111580..114234
/gene="SNF3"
/locus_tag="YDL194W"
/product="Snf3p"
/transcript_id="NM_001180254.1"
/db_xref="GI:296143177"
/db_xref="GeneID:851333"
CDS 111580..114234
/gene="SNF3"
/locus_tag="YDL194W"
/note="Plasma membrane low glucose sensor that regulates
glucose transport; contains 12 predicted transmembrane
segments and a long C-terminal tail required for induction
of hexose transporters; also senses fructose and mannose;
similar to Rgt2p"
/codon_start=1
/product="Snf3p"
/protein_id="NP_010087.1"
/db_xref="GI:6320007"
/db_xref="SGD:S000002353"
/db_xref="GeneID:851333"
/translation="MDPNSNSSSETLRQEKQGFLDKALQRVKGIALRRNNSNKDHTTD
DTTGSIRTPTSLQRQNSDRQSNMTSVFTDDISTIDDNSILFSEPPQKQSMMMSICVGV
FVAVGGFLFGYDTGLINSITSMNYVKSHVAPNHDSFTAQQMSILVSFLSLGTFFGALT
APFISDSYGRKPTIIFSTIFIFSIGNSLQVGAGGITLLIVGRVISGIGIGAISAVVPL
YQAEATHKSLRGAIISTYQWAITWGLLVSSAVSQGTHARNDASSYRIPIGLQYVWSSF
LAIGMFFLPESPRYYVLKDKLDEAAKSLSFLRGVPVHDSGLLEELVEIKATYDYEASF
GSSNFIDCFISSKSRPKQTLRMFTGIALQAFQQFSGINFIFYYGVNFFNKTGVSNSYL
VSFITYAVNVVFNVPGLFFVEFFGRRKVLVVGGVIMTIANFIVAIVGCSLKTVAAAKV
MIAFICLFIAAFSATWGGVVWVISAELYPLGVRSKCTAICAAANWLVNFICALITPYI
VDTGSHTSSLGAKIFFIWGSLNAMGVIVVYLTVYETKGLTLEEIDELYIKSSTGVVSP
KFNKDIRERALKFQYDPLQRLEDGKNTFVAKRNNFDDETPRNDFRNTISGEIDHSPNQ
KEVHSIPERVDIPTSTEILESPNKSSGMTVPVSPSLQDVPIPQTTEPAEIRTKYVDLG
NGLGLNTYNRGPPSLSSDSSEDYTEDEIGGPSSQGDQSNRSTMNDINDYMARLIHSTS
TASNTTDKFSGNQSTLRYHTASSHSDTTEEDSNLMDLGNGLALNAYNRGPPSILMNSS
DEEANGGETSDNLNTAQDLAGMKERMAQFAQSYIDKRGGLEPETQSNILSTSLSVMAD
TNEHNNEILHSSEENATNQPVNENNDLK"
gene 114672..115799
/gene="NUS1"
/locus_tag="YDL193W"
/db_xref="GeneID:851334"
mRNA 114672..115799
/gene="NUS1"
/locus_tag="YDL193W"
/product="Nus1p"
/transcript_id="NM_001180253.1"
/db_xref="GI:296143178"
/db_xref="GeneID:851334"
CDS 114672..115799
/gene="NUS1"
/locus_tag="YDL193W"
/EC_number="2.5.1.31"
/note="Putative prenyltransferase, required for cell
viability; proposed to be involved in protein trafficking
because tet-repressible mutant shows accumulation of
hypoglycosylated forms of CPY"
/codon_start=1
/product="Nus1p"
/protein_id="NP_010088.1"
/db_xref="GI:6320008"
/db_xref="SGD:S000002352"
/db_xref="GeneID:851334"
/translation="MPTMIKKDDKAMEPPNEKPHRKIERDDVPESSNHIPPPESGVLK
GGKVNSKTRALKAVTSIIADADENPQKKVNNETNGVQKQKTEDLSKRIGKFEYLFYKF
LLVLLYICFGLFRYGQYQYNKMKLRIFSIIYNHAYTPQLIRQDVIPLKKIPKRLAAIL
EVKPVGDVGGGVTGLLNDASEIVCWTVSAGIKHLMLYDYDGILQRNVPELRMEIHSNL
AKYFGPAHVPNYAVKIPHSNKIFYNLDGIETETDVGNEIEANQEKDKIAIEISLLSNR
DGRETIVDLTKTMAELCAVNELSVSDITMDLVDSELKQLVGPEPDLLLYFGPSLDLQG
FPPWHIRLTEFYWEKDNNEVIYSVFIRGLRQYAGCKVNVGK"
gene 116321..116866
/gene="ARF1"
/locus_tag="YDL192W"
/db_xref="GeneID:851335"
mRNA 116321..116866
/gene="ARF1"
/locus_tag="YDL192W"
/product="Arf1p"
/transcript_id="NM_001180252.1"
/db_xref="GI:296143179"
/db_xref="GeneID:851335"
CDS 116321..116866
/gene="ARF1"
/locus_tag="YDL192W"
/note="ADP-ribosylation factor; GTPase of the Ras
superfamily involved in regulation of coated vesicle
formation in intracellular trafficking within the Golgi;
ARF1 has a paralog, ARF2, that arose from the whole genome
duplication"
/codon_start=1
/product="Arf1p"
/protein_id="NP_010089.1"
/db_xref="GI:6320009"
/db_xref="SGD:S000002351"
/db_xref="GeneID:851335"
/translation="MGLFASKLFSNLFGNKEMRILMVGLDGAGKTTVLYKLKLGEVIT
TIPTIGFNVETVQYKNISFTVWDVGGQDRIRSLWRHYYRNTEGVIFVVDSNDRSRIGE
AREVMQRMLNEDELRNAAWLVFANKQDLPEAMSAAEITEKLGLHSIRNRPWFIQATCA
TSGEGLYEGLEWLSNSLKNST"
gene 117664..118517
/gene="RPL35A"
/locus_tag="YDL191W"
/gene_synonym="SOS1"
/db_xref="GeneID:851336"
mRNA join(117664..117666,118158..118517)
/gene="RPL35A"
/locus_tag="YDL191W"
/gene_synonym="SOS1"
/product="ribosomal 60S subunit protein L35A"
/transcript_id="NM_001180196.2"
/db_xref="GI:330443498"
/db_xref="GeneID:851336"
CDS join(117664..117666,118158..118517)
/gene="RPL35A"
/locus_tag="YDL191W"
/gene_synonym="SOS1"
/note="Ribosomal 60S subunit protein L35A; homologous to
mammalian ribosomal protein L35 and bacterial L29; RPL35A
has a paralog, RPL35B, that arose from the whole genome
duplication"
/codon_start=1
/product="ribosomal 60S subunit protein L35A"
/protein_id="NP_010145.1"
/db_xref="GI:6320065"
/db_xref="SGD:S000002350"
/db_xref="GeneID:851336"
/translation="MAGVKAYELRTKSKEQLASQLVDLKKELAELKVQKLSRPSLPKI
KTVRKSIACVLTVINEQQREAVRQLYKGKKYQPKDLRAKKTRALRRALTKFEASQVTE
KQRKKQIAFPQRKYAIKA"
gene complement(118707..121592)
/gene="UFD2"
/locus_tag="YDL190C"
/db_xref="GeneID:851337"
mRNA complement(118707..121592)
/gene="UFD2"
/locus_tag="YDL190C"
/product="ubiquitin-ubiquitin ligase UFD2"
/transcript_id="NM_001180250.2"
/db_xref="GI:330443499"
/db_xref="GeneID:851337"
CDS complement(118707..121592)
/gene="UFD2"
/locus_tag="YDL190C"
/note="Ubiquitin chain assembly factor (E4) that
cooperates with a ubiquitin-activating enzyme (E1), a
ubiquitin-conjugating enzyme (E2), and a ubiquitin protein
ligase (E3) to conjugate ubiquitin to substrates; also
functions as an E3"
/codon_start=1
/product="ubiquitin-ubiquitin ligase UFD2"
/protein_id="NP_010091.2"
/db_xref="GI:330443500"
/db_xref="SGD:S000002349"
/db_xref="GeneID:851337"
/translation="MTAIEDILQITTDPSDTRGYSLLKSEEVPQGSTLGVDFIDTLLL
YQLTENEKLDKPFEYLNDCFRRNQQQKRITKNKPNAESLHSTFQEIDRLVIGYGVVAL
QIENFCMNGAFINYITGIVSNVNSYTDFLSQIIQRAILEGTALDLLNAVFPTLLEYCN
KHVSHFDLNESVIYNNVLTIFELFVTFKPIAEIFTKIDGFFADYSCKPQDFERKTILG
PILSLSPIEAAVAIRNYGDNLLRSKQQTAMIHESLQAEHKVVIDRLFFIVDKLVRGSL
NSRTDMISYFAHIANKNHLRRADHPPFKELSSNGFMSNITLLLVRFSQPFLDISYKKI
DKIDANYFNNPSLFIDLSGETRLNSDFKEADAFYDKNRKTADSKPNFISDCFFLTLTY
LHYGLGGTLSFEEKMGSEIKALKEEIEKVKKIAANHDVFARFITAQLSKMEKALKTTE
SLRFALQGFFAHRSLQLEVFDFICGASTFLIRVVDPEHEFPFKQIKLPLIPDQIGVEN
VDNADFLRAHAPVPFKYYPEFVVEGPVNYSLYISKYQTSPIFRNPRLGSFVEFTTMVL
RCPELVSNPHLKGKLVQLLSVGAMPLTDNSPGFMMDIFEHDELVNKNLLYALLDFYVI
VEKTGSSSQFYDKFNSRYSISIILEELYYKIPSYKNQLIWQSQNNADFFVRFVARMLN
DLTFLLDEGLSNLAEVHNIQNELDNRARGAPPTREEEDKELQTRLASASRQAKSSCGL
ADKSMKLFEIYSKDIPAAFVTPEIVYRLASMLNYNLESLVGPKCGELKVKDPQSYSFN
PKDLLKALTTVYINLSEQSEFISAVAKDERSFNRNLFVRAVDILGRKTGLASPEFIEK
LLNFANKAEEQRKADEEEDLEYGDVPDEFLDPLMYTIMKDPVILPASKMNIDRSTIKA
HLLSDSTDPFNRMPLKLEDVTPNEELRQKILCFKKQKKEEAKHKASE"
gene 122216..123589
/gene="RBS1"
/locus_tag="YDL189W"
/db_xref="GeneID:851338"
mRNA 122216..123589
/gene="RBS1"
/locus_tag="YDL189W"
/product="Rbs1p"
/transcript_id="NM_001180249.1"
/db_xref="GI:296143182"
/db_xref="GeneID:851338"
CDS 122216..123589
/gene="RBS1"
/locus_tag="YDL189W"
/note="hypothetical protein, identified as a high copy
suppressor of psk1 psk2 mutations that confer
temperature-sensitivity for galactose utilization;
proposed to bind single-stranded nucleic acids via its R3H
domain"
/codon_start=1
/product="Rbs1p"
/protein_id="NP_010092.2"
/db_xref="GI:9755328"
/db_xref="SGD:S000002348"
/db_xref="GeneID:851338"
/translation="MTALDSRNWGLTPAMETGLFQKPQDRIFIIELENSIVSFINSNT
ESFQLRPMNSYYRLLSHQIAEYHNLNHVLARTQDSCVILFKGENFQKIEGKPLLQELQ
LNKKPEECASSSESIEKSNNNRIFRILKRKEVGNECDYKIDGNTRTPNSNLTANSNKD
QKIEIDDKSSTDLEQERIEKERLYEQRKQEIFDKLNKSEDDVKSTNSSGSSDSDNEWS
DWLNGDDSNTQTSNGSVSSSSPFNSSVTTIQVNKPQQQFYDSRRGRGGRRRGTNNYKD
AYRGQSRRNKENGGYQSGYSSPYLVYPPPQMGGNSLPTYPLMYNPAGPAPGPAPSPMV
MGNNTVFMNPYMYNMNPQGSCSFGTPIPMYPPYQYQYQYQYNTQYHSGPYSNTPSYNS
NNYTRSSANKYHHFQGKNSYSGAIPKRSDDSNSNKNEGIRRASVEGSPSSRDTDSVEM
KFDKLNI"
rep_origin 123617..123901
/note="ARS406;
Autonomously Replicating Sequence"
/db_xref="SGD:S000118429"
gene complement(123865..124998)
/gene="PPH22"
/locus_tag="YDL188C"
/gene_synonym="PPH2"
/db_xref="GeneID:851339"
mRNA complement(123865..124998)
/gene="PPH22"
/locus_tag="YDL188C"
/gene_synonym="PPH2"
/product="Pph22p"
/transcript_id="NM_001180248.1"
/db_xref="GI:296143183"
/db_xref="GeneID:851339"
CDS complement(123865..124998)
/gene="PPH22"
/locus_tag="YDL188C"
/gene_synonym="PPH2"
/EC_number="3.1.3.16"
/note="Catalytic subunit of protein phosphatase 2A (PP2A);
functionally redundant with Pph21p; methylated at C
terminus; forms alternate complexes with several
regulatory subunits; involved in signal transduction and
regulation of mitosis; protein abundance increases in
response to DNA replication stress"
/codon_start=1
/product="Pph22p"
/protein_id="NP_010093.1"
/db_xref="GI:6320013"
/db_xref="SGD:S000002347"
/db_xref="GeneID:851339"
/translation="MDMEIDDPMHGSDEDQLSPTLDEDMNSDDGKNNTKARSNDEDTD
EELEDFNFKPGSSGIADHKSSKPLKLTNTNINQLDQWIEHLSKCEPLSEDDVARLCKM
AVDVLQFEENVKPINVPVTICGDVHGQFHDLLELFKIGGPCPDTNYLFMGDYVDRGYY
SVETVSYLVAMKVRYPHRITILRGNHESRQITQVYGFYDECLRKYGSANVWKMFTDLF
DYFPVTALVDNKIFCLHGGLSPMIETIDQVRDLNRIQEVPHEGPMCDLLWSDPDDRGG
WGISPRGAGFTFGQDISEQFNHTNDLSLIARAHQLVMEGYSWSHQQNVVTIFSAPNYC
YRCGNQAAIMEVDENHNRQFLQYDPSVRPGEPTVTRKTPDYFL"
gene 125616..126449
/locus_tag="YDL186W"
/db_xref="GeneID:851340"
mRNA 125616..126449
/locus_tag="YDL186W"
/product="hypothetical protein"
/transcript_id="NM_001180246.1"
/db_xref="GI:296143184"
/db_xref="GeneID:851340"
CDS 125616..126449
/locus_tag="YDL186W"
/note="hypothetical protein; YDL186W is not an essential
gene"
/codon_start=1
/product="hypothetical protein"
/protein_id="NP_010095.1"
/db_xref="GI:6320014"
/db_xref="SGD:S000002345"
/db_xref="GeneID:851340"
/translation="MQCNTSIEDGLDGGDITFPSYSPEAEAQNRFLPRSEFPSVRQLV
ISKQKSRRRREENVFVGKMEDVLVKWRPPASSHRGAIEAINGTHPYQLSTAQFNSRRS
DPFGSTKRDESVRSIVESFTDWWKRNSKMFFRDEEEGVRTEHSASQDDQELQLFEEDL
FSFHLSPNDMSTRNSEHQVQTPVLFPYEAPTRTKQNPAERKVIEIGDGEELSIYRDVY
SNPIPVSYLDTLNLNHSMSVRQTQQQQQQRQQQQYVDSSSAFQCCTDSNWARIFFCHH
D"
gene 126787..130002
/gene="VMA1"
/locus_tag="YDL185W"
/gene_synonym="CLS8; TFP1"
/db_xref="GeneID:851342"
mRNA 126787..130002
/gene="VMA1"
/locus_tag="YDL185W"
/gene_synonym="CLS8; TFP1"
/product="Vma1p"
/transcript_id="NM_001180245.1"
/db_xref="GI:296143185"
/db_xref="GeneID:851342"
CDS 126787..130002
/gene="VMA1"
/locus_tag="YDL185W"
/gene_synonym="CLS8; TFP1"
/EC_number="3.1.-.-"
/EC_number="3.6.3.14"
/note="Subunit A of the eight-subunit V1 peripheral
membrane domain of the vacuolar H+-ATPase; protein
precursor undergoes self-catalyzed splicing to yield the
extein Tfp1p and the intein Vde (PI-SceI), which is a
site-specific endonuclease"
/codon_start=1
/product="Vma1p"
/protein_id="NP_010096.1"
/db_xref="GI:6320016"
/db_xref="SGD:S000002344"
/db_xref="GeneID:851342"
/translation="MAGAIENARKEIKRISLEDHAESEYGAIYSVSGPVVIAENMIGC
AMYELVKVGHDNLVGEVIRIDGDKATIQVYEETAGLTVGDPVLRTGKPLSVELGPGLM
ETIYDGIQRPLKAIKEESQSIYIPRGIDTPALDRTIKWQFTPGKFQVGDHISGGDIYG
SVFENSLISSHKILLPPRSRGTITWIAPAGEYTLDEKILEVEFDGKKSDFTLYHTWPV
RVPRPVTEKLSADYPLLTGQRVLDALFPCVQGGTTCIPGAFGCGKTVISQSLSKYSNS
DAIIYVGCFAKGTNVLMADGSIECIENIEVGNKVMGKDGRPREVIKLPRGRETMYSVV
QKSQHRAHKSDSSREVPELLKFTCNATHELVVRTPRSVRRLSRTIKGVEYFEVITFEM
GQKKAPDGRIVELVKEVSKSYPISEGPERANELVESYRKASNKAYFEWTIEARDLSLL
GSHVRKATYQTYAPILYENDHFFDYMQKSKFHLTIEGPKVLAYLLGLWIGDGLSDRAT
FSVDSRDTSLMERVTEYAEKLNLCAEYKDRKEPQVAKTVNLYSKVVRGNGIRNNLNTE
NPLWDAIVGLGFLKDGVKNIPSFLSTDNIGTRETFLAGLIDSDGYVTDEHGIKATIKT
IHTSVRDGLVSLARSLGLVVSVNAEPAKVDMNGTKHKISYAIYMSGGDVLLNVLSKCA
GSKKFRPAPAAAFARECRGFYFELQELKEDDYYGITLSDDSDHQFLLANQVVVHNCGE
RGNEMAEVLMEFPELYTEMSGTKEPIMKRTTLVANTSNMPVAAREASIYTGITLAEYF
RDQGKNVSMIADSSSRWAEALREISGRLGEMPADQGFPAYLGAKLASFYERAGKAVAL
GSPDRTGSVSIVAAVSPAGGDFSDPVTTATLGITQVFWGLDKKLAQRKHFPSINTSVS
YSKYTNVLNKFYDSNYPEFPVLRDRMKEILSNAEELEQVVQLVGKSALSDSDKITLDV
ATLIKEDFLQQNGYSTYDAFCPIWKTFDMMRAFISYHDEAQKAVANGANWSKLADSTG
DVKHAVSSSKFFEPSRGEKEVHGEFEKLLSTMQERFAESTD"
gene complement(130407..130484)
/gene="RPL41A"
/locus_tag="YDL184C"
/gene_synonym="RPL47A"
/db_xref="GeneID:851344"
mRNA complement(130407..130484)
/gene="RPL41A"
/locus_tag="YDL184C"
/gene_synonym="RPL47A"
/product="ribosomal 60S subunit protein L41A"
/transcript_id="NM_001180244.1"
/db_xref="GI:296143186"
/db_xref="GeneID:851344"
CDS complement(130407..130484)
/gene="RPL41A"
/locus_tag="YDL184C"
/gene_synonym="RPL47A"
/note="Ribosomal 60S subunit protein L41A; comprises only
25 amino acids; rpl41a rpl41b double null mutant is
viable; homologous to mammalian ribosomal protein L41, no
bacterial homolog; RPL41A has a paralog, RPL41B, that
arose from the whole genome duplication"
/codon_start=1
/product="ribosomal 60S subunit protein L41A"
/protein_id="NP_010097.1"
/db_xref="GI:6320017"
/db_xref="SGD:S000002343"
/db_xref="GeneID:851344"
/translation="MRAKWRKKRTRRLKRKRRKVRARSK"
gene complement(130871..131833)
/locus_tag="YDL183C"
/db_xref="GeneID:851345"
mRNA complement(130871..131833)
/locus_tag="YDL183C"
/product="hypothetical protein"
/transcript_id="NM_001180243.1"
/db_xref="GI:296143187"
/db_xref="GeneID:851345"
CDS complement(130871..131833)
/locus_tag="YDL183C"
/note="Mitochondrial inner-membrane protein thought to be
involved in the formation of an active mitochondrial K+/H+
exchanger (KHE) system; non-essential gene"
/codon_start=1
/product="hypothetical protein"
/protein_id="NP_010098.1"
/db_xref="GI:6320018"
/db_xref="SGD:S000002342"
/db_xref="GeneID:851345"
/translation="MIRSIFIPPTSITATSRLFYGMRAYSTKLEKASLQKYLHDPVKV
TVIPITDKESFIYYKHTDNLFNSQSRILKAEKWIVEKSAKLWRKLKKSPKSYNKKIVS
MVQSLLNSTPWSENSLLTIPSESYILKRIKGEKDKTQEIRLTLKDYTVKAEQVDTQPL
HVYYPPGISSPDECLRQMKKLYQEGLIYHKKWTLYCLLGLPLTIPLILIPLIPNVPGF
YLSYRAYVNIKAYLGAKHLKSLLESSKQNLEFRELLGYTEVYKRGTSSRTQGNQKESK
GAPELLLNKKTLPLILDFLEVHELESDLNKVILQESKSQEKNKI"
gene 133437..134723
/gene="LYS20"
/locus_tag="YDL182W"
/db_xref="GeneID:851346"
mRNA 133437..134723
/gene="LYS20"
/locus_tag="YDL182W"
/product="homocitrate synthase LYS20"
/transcript_id="NM_001180242.1"
/db_xref="GI:296143188"
/db_xref="GeneID:851346"
CDS 133437..134723
/gene="LYS20"
/locus_tag="YDL182W"
/EC_number="2.3.3.14"
/note="Homocitrate synthase isozyme; catalyzes the
condensation of acetyl-CoA and alpha-ketoglutarate to form
homocitrate, which is the first step in the lysine
biosynthesis pathway; LYS20 has a paralog, LYS21, that
arose from the whole genome duplication"
/codon_start=1
/product="homocitrate synthase LYS20"
/protein_id="NP_010099.1"
/db_xref="GI:6320019"
/db_xref="SGD:S000002341"
/db_xref="GeneID:851346"
/translation="MTAAKPNPYAAKPGDYLSNVNNFQLIDSTLREGEQFANAFFDTE
KKIEIARALDDFGVDYIELTSPVASEQSRKDCEAICKLGLKAKILTHIRCHMDDAKVA
VETGVDGVDVVIGTSKFLRQYSHGKDMNYIAKSAVEVIEFVKSKGIEIRFSSEDSFRS
DLVDLLNIYKTVDKIGVNRVGIADTVGCANPRQVYELIRTLKSVVSCDIECHFHNDTG
CAIANAYTALEGGARLIDVSVLGIGERNGITPLGGLMARMIVAAPDYVKSKYKLHKIR
DIENLVADAVEVNIPFNNPITGFCAFTHKAGIHAKAILANPSTYEILDPHDFGMKRYI
HFANRLTGWNAIKARVDQLNLNLTDDQIKEVTAKIKKLGDVRSLNIDDVDSIIKNFHA
EVSTPQVLSAKKNKKNDSDVPELATIPAAKRTKPSA"
gene 135179..135436
/gene="INH1"
/locus_tag="YDL181W"
/db_xref="GeneID:851347"
mRNA 135179..135436
/gene="INH1"
/locus_tag="YDL181W"
/product="Inh1p"
/transcript_id="NM_001180241.1"
/db_xref="GI:296143189"
/db_xref="GeneID:851347"
CDS 135179..135436
/gene="INH1"
/locus_tag="YDL181W"
/note="Protein that inhibits ATP hydrolysis by the
F1F0-ATP synthase; inhibitory function is enhanced by
stabilizing proteins Stf1p and Stf2p; has similarity to
Stf1p; has a calmodulin-binding motif and binds calmodulin
in vitro"
/codon_start=1
/product="Inh1p"
/protein_id="NP_010100.1"
/db_xref="GI:6320020"
/db_xref="SGD:S000002340"
/db_xref="GeneID:851347"
/translation="MLPRSALARSLQLQRGVAARFYSEGSTGTPRGSGSEDSFVKRER
ATEDFFVRQREKEQLRHLKEQLEKQRKKIDSLENKIDSMTK"
gene 135896..137539
/locus_tag="YDL180W"
/db_xref="GeneID:851374"
mRNA 135896..137539
/locus_tag="YDL180W"
/product="hypothetical protein"
/transcript_id="NM_001180240.1"
/db_xref="GI:296143190"
/db_xref="GeneID:851374"
CDS 135896..137539
/locus_tag="YDL180W"
/note="hypothetical protein; green fluorescent protein
(GFP)-fusion protein localizes to the vacuole"
/codon_start=1
/product="hypothetical protein"
/protein_id="NP_010101.1"
/db_xref="GI:6320021"
/db_xref="SGD:S000002339"
/db_xref="GeneID:851374"
/translation="MVRLNHAASYFMPIFCSTRPHIVILSALFSISLFSLFYASSELL
LHQYDDPLMFKPNSQDYFRTFLLGLFSPFLYYFLKTFLFNINQRFLILNLIVDFPIND
VFMLLILIGLAYPQVQDHEGGTIKHKECSWHIIPRQAYIFGISWALGEFTICIIGNLF
NYQEIADPNINSGFTHQESANTYCNNNDMSHNDDCGCSTEYRPNVVDRSDITLSKCIE
VRNDSSSISNNVYSSEYHPIKPLRSSSSTYGSIRQQPHENKKQLHVPDNSQDDTIIMM
NPIDNSLKLTTLDTGDLSFPIDEEQPILKKSFGYTWAVPNENTQNTTKSFTPIKRFIA
FSTAYQLVTGLLLMILVVGSNIMLTIGESLILSMYFVYVRGHEGLFTPVVNYFGSRTI
SNFILCVIIPFISLNFLINTSIYLRRELDDWFNNSQGEFEDDDENTISKRVATNQEYQ
HPLSANYISMDSPDVINSSPGHFGMNSGQLLGNTTLYYGSLNGDDDDMTNDSALLRFC
KKLVKNWRALARNDSFVLGVMVSWSLLVFVTGILSTVYI"
gene 138291..139205
/gene="PCL9"
/locus_tag="YDL179W"
/db_xref="GeneID:851375"
mRNA 138291..139205
/gene="PCL9"
/locus_tag="YDL179W"
/product="Pcl9p"
/transcript_id="NM_001180239.1"
/db_xref="GI:296143191"
/db_xref="GeneID:851375"
CDS 138291..139205
/gene="PCL9"
/locus_tag="YDL179W"
/note="Cyclin, forms a functional kinase complex with
Pho85p cyclin-dependent kinase (Cdk), expressed in late
M/early G1 phase, activated by Swi5p"
/codon_start=1
/product="Pcl9p"
/protein_id="NP_010102.1"
/db_xref="GI:6320022"
/db_xref="SGD:S000002338"
/db_xref="GeneID:851375"
/translation="MISDYDALLQFNKKPVSQEMIQFLATSTASIIKIRENNNPIQGC
RPPDLSIFIKNVVIQSNVQTPTLMATSVYLNKLKSVIPKNVYGINTTRHRIFLGCLIL
AAKTLNDSSPWNKHWTTYTEGLLRIREVNTIERELLEYLNWDVRITTPDLIDSLSYFL
GPIKEQLFLQRRQEMLLFNAPSPGQLKEYINHRRPVSHSRTSSAISVPSLTSMATVST
TDSRSSLLAKYQPSLPLVESDNFNKKNHVPLRNNNDICNNFRAEENIHSVNHIDVTMG
SSPVMSHKPTIHQRLNFTRRGWSSFFKQ"
gene 139522..141114
/gene="DLD2"
/locus_tag="YDL178W"
/gene_synonym="AIP2"
/db_xref="GeneID:851376"
mRNA 139522..141114
/gene="DLD2"
/locus_tag="YDL178W"
/gene_synonym="AIP2"
/product="Dld2p"
/transcript_id="NM_001180238.1"
/db_xref="GI:296143192"
/db_xref="GeneID:851376"
CDS 139522..141114
/gene="DLD2"
/locus_tag="YDL178W"
/gene_synonym="AIP2"
/EC_number="1.1.2.4"
/note="D-lactate dehydrogenase, located in the
mitochondrial matrix"
/codon_start=1
/product="Dld2p"
/protein_id="NP_010103.1"
/db_xref="GI:6320023"
/db_xref="SGD:S000002337"
/db_xref="GeneID:851376"
/translation="MLRNILVRSTGSNFKFAGRYMKSSALLGYYRRVNYYSTKIQTRL
TSENYPDVHRDPRFKKLTSDDLNYFKSILSEQEILRASESEDLSFYNEDWMRKYKGQS
KLVLRPKSVEKVSLILNYCNDEKIAVVPQGGNTGLVGGSVPIFDELILSLANLNKIRD
FDPVSGILKCDAGVILENANNYVMEQNYMFPLDLGAKGSCHVGGVVATNAGGLRLLRY
GSLHGSVLGLEVVMPNGQIVNSMHSMRKDNTGYDLKQLFIGSEGTIGIITGVSILTVP
KPKAFNVSYLSVESFEDVQKVFVRARQELSEILSAFEFMDAKSQVLAKSQLKDAAFPL
EDEHPFYILIETSGSNKDHDDSKLETFLENVMEEGIVTDGVVAQDETELQNLWKWREM
IPEASQANGGVYKYDVSLPLKDLYSLVEATNARLSEAELVGDSPKPVVGAIGYGHVGD
GNLHLNVAVREYNKNIEKTLEPFVYEFVSSKHGSVSAEHGLGFQKKNYIGYSKSPEEV
KMMKDLKVHYDPNGILNPYKYI"
gene complement(141209..141721)
/locus_tag="YDL177C"
/db_xref="GeneID:851377"
mRNA complement(141209..141721)
/locus_tag="YDL177C"
/product="hypothetical protein"
/transcript_id="NM_001180237.1"
/db_xref="GI:296143193"
/db_xref="GeneID:851377"
CDS complement(141209..141721)
/locus_tag="YDL177C"
/note="hypothetical protein; similar to the mouse IMPACT
gene; YDL177C is not an essential gene"
/codon_start=1
/product="hypothetical protein"
/protein_id="NP_010104.1"
/db_xref="GI:6320024"
/db_xref="SGD:S000002336"
/db_xref="GeneID:851377"
/translation="MSKNVGKLVKIWNESEVLVDRKSKFQARCCPLQNQKDIPSILQE
LTQNNKSVSKASHMHMYAWRTAEVSNNLHLQQEQKKKGNKANKSNNSHVNKSRNITVQ
PKNIEQGCADCGEAGAGQRLLTLLERANIFNVLVIVTRWYGGTPLGSSRFRHISTCAV
ETLKKGGFLP"
gene 142097..144223
/locus_tag="YDL176W"
/db_xref="GeneID:851378"
mRNA 142097..144223
/locus_tag="YDL176W"
/product="hypothetical protein"
/transcript_id="NM_001180236.1"
/db_xref="GI:296143194"
/db_xref="GeneID:851378"
CDS 142097..144223
/locus_tag="YDL176W"
/note="hypothetical protein, predicted by computational
methods to be involved in fructose-1,6-bisphosphatase
(Fbp1p) degradation; interacts with components of the GID
complex; YDL176W is not an essential gene"
/codon_start=1
/product="hypothetical protein"
/protein_id="NP_010105.1"
/db_xref="GI:6320025"
/db_xref="SGD:S000002335"
/db_xref="GeneID:851378"
/translation="MATGRIQFAVSTPCNTKGKPSGYRLFEFKNDRLALVPSERGCTK
VDVNANIQAFCYLRPNGRDTSISPDATHILDSCDYMVLAKSNGFIEIISNYQYKIKNG
LRLAPSYILRCTPEDFESNFFSDYMIAGLEYSQGLLYCCMCSGRIYVFVMNLPTDYIQ
YKNMYNPMFPDCFFKVHHDNNTTHSSEEEKLFEGSTRYTGRSCSKHICYFLLPIEPSH
LRSSPVVSSFCNMYQGLPIYRPSMYLHIERGISTFHINPLDRFCFMTVSPRSPLFIRK
IILPLTYVTFLSTFISLKNSIQGDTCGEILSWDNVAQQNGFGSLFSWISNKFTFDTDI
INSTIWDDIVKYSGTGMLDSGIVWKQRQGHAKDDIYELFHTQDMLGSSRRNSSFSTAS
SEPRPLSRRRRESFQALTRDAFRERMDVPCSTKWELDSFIRGLRRNTFMVDFEIVEKI
SHRNGNDGVNEDDNTTDESDETMTSFLTDNYKKMDIVCIDHFVTLSAFRPRYYDEPII
KIDSLSNKNGSENGTNEEEWAESQMKVDGQVIDDETAQFKQALGNLCSFKKLFMLDDS
LCFILDTHGVLLINRFEIKNTKNLLRNSKDTIRIIPHDFGLINDTIVIINDIDVGTDN
VCALTFHLVVTSMAGEITVLKGEFFKNCRLGRIKLCDSLKLNRKDRFVDKLALIDYDG
LNAQKRRLDYDEKDLYTFIVKKVKRD"
gene complement(144484..145518)
/gene="AIR2"
/locus_tag="YDL175C"
/db_xref="GeneID:851379"
mRNA complement(144484..145518)
/gene="AIR2"
/locus_tag="YDL175C"
/product="Air2p"
/transcript_id="NM_001180235.1"
/db_xref="GI:296143195"
/db_xref="GeneID:851379"
CDS complement(144484..145518)
/gene="AIR2"
/locus_tag="YDL175C"
/note="RNA-binding subunit of the TRAMP nuclear RNA
surveillance complex; involved in nuclear RNA processing
and degradation; involved in TRAMP complex assembly as a
bridge between Mtr4p and Trf4p; stimulates the poly(A)
polymerase activity of Pap2p in vitro; has 5 zinc knuckle
motifs; AIR2 has a paralog, AIR1, that arose from the
whole genome duplication"
/codon_start=1
/product="Air2p"
/protein_id="NP_010106.1"
/db_xref="GI:6320026"
/db_xref="SGD:S000002334"
/db_xref="GeneID:851379"
/translation="MEKNTAPFVVDTAPTTPPDKLVAPSIEEVNSNPNELRALRGQGR
YFGVSDDDKDAIKEAAPKCNNCSQRGHLKKDCPHIICSYCGATDDHYSRHCPKAIQCS
KCDEVGHYRSQCPHKWKKVQCTLCKSKKHSKERCPSIWRAYILVDDNEKAKPKVLPFH
TIYCYNCGGKGHFGDDCKEKRSSRVPNEDGSAFTGSNLSVELKQEYYRHMNRNSDENE
DYQFSESIYDEDPLPRPSHKRHSQNDHSHSGRNKRRASNFHPPPYQKSNVIQPTIRGE
TLSLNNNISKNSRYQNTKVNVSSISENMYGSRYNPSTYVDNNSISNSSNYRNYNSYQP
YRSGTLGKRR"
gene complement(145826..147589)
/gene="DLD1"
/locus_tag="YDL174C"
/db_xref="GeneID:851380"
mRNA complement(145826..147589)
/gene="DLD1"
/locus_tag="YDL174C"
/product="Dld1p"
/transcript_id="NM_001180234.1"
/db_xref="GI:296143196"
/db_xref="GeneID:851380"
CDS complement(145826..147589)
/gene="DLD1"
/locus_tag="YDL174C"
/EC_number="1.1.2.4"
/note="D-lactate dehydrogenase, oxidizes D-lactate to
pyruvate, transcription is heme-dependent, repressed by
glucose, and derepressed in ethanol or lactate; located in
the mitochondrial inner membrane"
/codon_start=1
/product="Dld1p"
/protein_id="NP_010107.1"
/db_xref="GI:6320027"
/db_xref="SGD:S000002333"
/db_xref="GeneID:851380"
/translation="MLWKRTCTRLIKPIAQPRGRLVRRSCYRYASTGTGSTDSSSQWL
KYSVIASSATLFGYLFAKNLYSRETKEDLIEKLEMVKKIDPVNSTLKLSSLDSPDYLH
DPVKIDKVVEDLKQVLGNKPENYSDAKSDLDAHSDTYFNTHHPSPEQRPRIILFPHTT
EEVSKILKICHDNNMPVVPFSGGTSLEGHFLPTRIGDTITVDLSKFMNNVVKFDKLDL
DITVQAGLPWEDLNDYLSDHGLMFGCDPGPGAQIGGCIANSCSGTNAYRYGTMKENII
NMTIVLPDGTIVKTKKRPRKSSAGYNLNGLFVGSEGTLGIVTEATVKCHVKPKAETVA
VVSFDTIKDAAACASNLTQSGIHLNAMELLDENMMKLINASESTDRCDWVEKPTMFFK
IGGRSPNIVNALVDEVKAVAQLNHCNSFQFAKDDDEKLELWEARKVALWSVLDADKSK
DKSAKIWTTDVAVPVSQFDKVIHETKKDMQASKLINAIVGHAGDGNFHAFIVYRTPEE
HETCSQLVDRMVKRALNAEGTCTGEHGVGIGKREYLLEELGEAPVDLMRKIKLAIDPK
RIMNPDKIFKTDPNEPANDYR"
gene 148191..149078
/gene="PAR32"
/locus_tag="YDL173W"
/db_xref="GeneID:851381"
mRNA 148191..149078
/gene="PAR32"
/locus_tag="YDL173W"
/product="Par32p"
/transcript_id="NM_001180233.1"
/db_xref="GI:296143197"
/db_xref="GeneID:851381"
CDS 148191..149078
/gene="PAR32"
/locus_tag="YDL173W"
/note="hypothetical protein; hyperphosphorylated upon
rapamycin treatment in a Tap42p-dependent manner; green
fluorescent protein (GFP)-fusion protein localizes to the
cytoplasm; PAR32 is not an essential gene"
/codon_start=1
/product="Par32p"
/protein_id="NP_010108.1"
/db_xref="GI:6320028"
/db_xref="SGD:S000002332"
/db_xref="GeneID:851381"
/translation="MATFNPQNEMENQARVQEYKVSTGRGGAGNIHKSMSKPSPVLLP
LKSNSKTVANNNNNGSNQEKVPRFAIGRGGAGNIFHDPHLTRSAQQLDSNDNINYNDV
INDIDDYISPITSDMVDEGGSNPVTNTRSRISATRSHQSLHATTSSPNNNAPIVVGRG
GAGNIFFNKKKVASNGGNEEDEIRGGNIEDEDTINANEDNLFVVTSNGNALAAIKSTS
KKPKNKLKGKSAPEKFAIGRGGAGNIISPKSSRNTINHNLNDDDEDKFNLKDDNGKEK
KKKKKKKSGFFSSLKTMFN"
gene complement(149203..155640)
/gene="GLT1"
/locus_tag="YDL171C"
/db_xref="GeneID:851383"
mRNA complement(149203..155640)
/gene="GLT1"
/locus_tag="YDL171C"
/product="glutamate synthase (NADH)"
/transcript_id="NM_001180231.1"
/db_xref="GI:296143198"
/db_xref="GeneID:851383"
CDS complement(149203..155640)
/gene="GLT1"
/locus_tag="YDL171C"
/EC_number="1.4.1.14"
/note="NAD(+)-dependent glutamate synthase (GOGAT),
synthesizes glutamate from glutamine and
alpha-ketoglutarate; with Gln1p, forms the secondary
pathway for glutamate biosynthesis from ammonia;
expression regulated by nitrogen source"
/codon_start=1
/product="glutamate synthase (NADH)"
/protein_id="NP_010110.1"
/db_xref="GI:6320030"
/db_xref="SGD:S000002330"
/db_xref="GeneID:851383"
/translation="MPVLKSDNFDPLEEAYEGGTIQNYNDEHHLHKSWANVIPDKRGL
YDPDYEHDACGVGFVANKHGEQSHKIVTDARYLLVNMTHRGAVSSDGNGDGAGILLGI
PHEFMKREFKLDLDLDIPEMGKYAVGNVFFKKNEKNNKKNLIKCQKIFEDLAASFNLS
VLGWRNVPVDSTILGDVALSREPTILQPLLVPLYDEKQPEFNETKFRTQLYLLRKEAS
LQIGLENWFYVCSLNNTTIVYKGQLTPAQVYNYYPDLTNAHFKSHMALVHSRFSTNTF
PSWDRAQPLRWLAHNGEINTLRGNKNWMRSREGVMNSATFKDELDKLYPIIEEGGSDS
AALDNVLELLTINGTLSLPEAVMMMVPEAYHKDMDSDLKAWYDWAACLMEPWDGPALL
TFTDGRYCGAILDRNGLRPCRYYITSDDRVICASEVGVIPIENSLVVQKGKLKPGDLF
LVDTQLGEMVDTKKLKSQISKRQDFKSWLSKVIKLDDLLSKTANLVPKEFISQDSLSL
KVQSDPRLLANGYTFEQVTFLLTPMALTGKEALGSMGNDAPLACLNENPVLLYDYFRQ
LFAQVTNPPIDPIREANVMSLECYVGPQGNLLEMHSSQCDRLLLKSPILHWNEFQALK
NIEAAYPSWSVAEIDITFDKSEGLLGYTDTIDKITKLASEAIDDGKKILIITDRKMGA
NRVSISSLIAISCIHHHLIRNKQRSQVALILETGEAREIHHFCVLLGYGCDGVYPYLA
METLVRMNREGLLRNVNNDNDTLEEGQILENYKHAIDAGILKVMSKMGISTLASYKGA
QIFEALGLDNSIVDLCFTGTSSRIRGVTFEYLAQDAFSLHERGYPSRQTISKSVNLPE
SGEYHFRDGGYKHVNEPTAIASLQDTVRNKNDVSWQLYVKKEMEAIRDCTLRGLLELD
FENSVSIPLEQVEPWTEIARRFASGAMSYGSISMEAHSTLAIAMNRLGAKSNCGEGGE
DAERSAVQENGDTMRSAIKQVASARFGVTSYYLSDADEIQIKIAQGAKPGEGGELPAH
KVSKDIAKTRHSTPNVGLISPPPHHDIYSIEDLKQLIYDLKCANPRAGISVKLVSEVG
VGIVASGVAKAKADHILVSGHDGGTGAARWTSVKYAGLPWELGLAETHQTLVLNDLRR
NVVVQTDGQLRTGFDIAVAVLLGAESFTLATVPLIAMGCVMLRRCHLNSCAVGIATQD
PYLRSKFKGQPEHVINFFYYLIQDLRQIMAKLGFRTIDEMVGHSEKLKKRDDVNAKAI
NIDLSPILTPAHVIRPGVPTKFTKKQDHKLHTRLDNKLIDEAEVTLDRGLPVNIDASI
INTDRALGSTLSYRVSKKFGEDGLPKDTVVVNIEGSAGQSFGAFLASGITFILNGDAN
DYVGKGLSGGIIVIKPPKDSKFKSDENVIVGNTCFYGATSGTAFISGSAGERFGVRNS
GATIVVERIKGNNAFEYMTGGRAIVLSQMESLNAFSGATGGIAYCLTSDYDDFVGKIN
KDTVELESLCDPVEIAFVKNLIQEHWNYTQSDLAARILGNFNHYLKDFVKVIPTDYKK
VLLKEKAEAAKAKAKATSEYLKKFRSNQEVDDEVNTLLIANQKAKEQEKKKSITISNK
ATLKEPKVVDLEDAVPDSKQLEKNSERIEKTRGFMIHKRRHETHRDPRTRVNDWKEFT
NPITKKDAKYQTARCMDCGTPFCLSDTGCPLSNIIPKFNELLFKNQWKLALDKLLETN
NFPEFTGRVCPAPCEGACTLGIIEDPVGIKSVERIIIDNAFKEGWIKPCPPSTRTGFT
VGVIGSGPAGLACADMLNRAGHTVTVYERSDRCGGLLMYGIPNMKLDKAIVQRRIDLL
SAEGIDFVTNTEIGKTISMDELKNKHNAVVYAIGSTIPRDLPIKGRELKNIDFAMQLL
ESNTKALLNKDLEIIREKIQGKKVIVVGGGDTGNDCLGTSVRHGAASVLNFELLPEPP
VERAKDNPWPQWPRVMRVDYGHAEVKEHYGRDPREYCILSKEFIGNDEGEVTAIRTVR
VEWKKSQSGVWQMVEIPNSEEIFEADIILLSMGFVGPELINGNDNEVKKTRRGTIATL
DDSSYSIDGGKTFACGDCRRGQSLIVWAIQEGRKCAASVDKFLMDGTTYLPSNGGIVQ
RDYKLLKELASQV"
gene 156318..157904
/gene="UGA3"
/locus_tag="YDL170W"
/db_xref="GeneID:851384"
mRNA 156318..157904
/gene="UGA3"
/locus_tag="YDL170W"
/product="Uga3p"
/transcript_id="NM_001180230.1"
/db_xref="GI:296143199"
/db_xref="GeneID:851384"
CDS 156318..157904
/gene="UGA3"
/locus_tag="YDL170W"
/note="Transcriptional activator necessary for
gamma-aminobutyrate (GABA)-dependent induction of GABA
genes (such as UGA1, UGA2, UGA4); zinc-finger
transcription factor of the Zn(2)-Cys(6) binuclear cluster
domain type; localized to the nucleus"
/codon_start=1
/product="Uga3p"
/protein_id="NP_010111.1"
/db_xref="GI:6320031"
/db_xref="SGD:S000002329"
/db_xref="GeneID:851384"
/translation="MNYGVEKLKLKYSKHGCITCKIRKKRCSEDKPVCRDCRRLSFPC
IYISESVDKQSLKKIKADIQHQLISKKRKHAPDSAQKAAVATRTRRVGSDEQDNQVYL
SKPLEDCISQKLDSMGLQLYNYYRSHLANIISIAPMNQNYYLNIFLPMAHENDGILFA
ILAWSANHLSISSSNELRKDEIFVNLANKYTYMSLSHLKTNEGSSACAKLGFLYSLAQ
ILILCGSEICQGDVKFWKILLNIGKNLIENHVGKDVSRILTTTTEEPSLEERIIFPNF
NSVVKYWLIVNFIYHDILNFNTTSFPIEQYEKFFQRDQNSLPSSANFIESIDSPIEEI
DPLIGINKPILLLLGQVTNLTRFLQTMEQEEMLEHGDKILSLQVEIYKLQPSLMALEH
LDDEKKFYYLELFEIMKISTLMFFQLTLLKIDKDSLELQILRNKLDSKLDKVIGTFLE
GSLCFPLFIYGVCIQVEDMEKKIDLEAKFDDILKRYKCYNFQNARLLIRKIWQNEADG
ISEHDLVHMIDELDYNINFA"
gene complement(158064..158735)
/gene="UGX2"
/locus_tag="YDL169C"
/db_xref="GeneID:851385"
mRNA complement(158064..158735)
/gene="UGX2"
/locus_tag="YDL169C"
/product="Ugx2p"
/transcript_id="NM_001180229.1"
/db_xref="GI:296143200"
/db_xref="GeneID:851385"
CDS complement(158064..158735)
/gene="UGX2"
/locus_tag="YDL169C"
/note="hypothetical protein, transcript accumulates in
response to any combination of stress conditions"
/codon_start=1
/product="Ugx2p"
/protein_id="NP_010112.1"
/db_xref="GI:6320032"
/db_xref="SGD:S000002328"
/db_xref="GeneID:851385"
/translation="MEDKEKLIVYSNTSSVFTYSAEIRPNFKISVSQSQGFAWNQDLF
ATQYQQSYKVVYDAHEDNFDELILKIKGKLKTKSNKRAKMKSKTKLTRTAKQRRESPV
CERDESDEDNDSDHYQRIQVLDGHEFPRANRYKSVWAHDVHSNEDSTSDGESNHDIDM
IGGTGTSYAGAAIMDRPRRKSERSISFVEDSKTGDYRYQTGQVDVVEVDSDTPENNHL
KWLIK"
gene 159604..160764
/gene="SFA1"
/locus_tag="YDL168W"
/gene_synonym="ADH5"
/db_xref="GeneID:851386"
mRNA 159604..160764
/gene="SFA1"
/locus_tag="YDL168W"
/gene_synonym="ADH5"
/product="bifunctional alcohol
dehydrogenase/S-(hydroxymethyl)glutathione dehydrogenase"
/transcript_id="NM_001180228.1"
/db_xref="GI:296143201"
/db_xref="GeneID:851386"
CDS 159604..160764
/gene="SFA1"
/locus_tag="YDL168W"
/gene_synonym="ADH5"
/EC_number="1.1.1.284"
/EC_number="1.1.1.1"
/note="Bifunctional alcohol dehydrogenase and formaldehyde
dehydrogenase; formaldehyde dehydrogenase activity is
glutathione-dependent; functions in formaldehyde
detoxification and formation of long chain and complex
alcohols, regulated by Hog1p-Sko1p; protein abundance
increases in response to DNA replication stress"
/codon_start=1
/product="bifunctional alcohol
dehydrogenase/S-(hydroxymethyl)glutathione dehydrogenase"
/protein_id="NP_010113.1"
/db_xref="GI:6320033"
/db_xref="SGD:S000002327"
/db_xref="GeneID:851386"
/translation="MSAATVGKPIKCIAAVAYDAKKPLSVEEITVDAPKAHEVRIKIE
YTAVCHTDAYTLSGSDPEGLFPCVLGHEGAGIVESVGDDVITVKPGDHVIALYTAECG
KCKFCTSGKTNLCGAVRATQGKGVMPDGTTRFHNAKGEDIYHFMGCSTFSEYTVVADV
SVVAIDPKAPLDAACLLGCGVTTGFGAALKTANVQKGDTVAVFGCGTVGLSVIQGAKL
RGASKIIAIDINNKKKQYCSQFGATDFVNPKEDLAKDQTIVEKLIEMTDGGLDFTFDC
TGNTKIMRDALEACHKGWGQSIIIGVAAAGEEISTRPFQLVTGRVWKGSAFGGIKGRS
EMGGLIKDYQKGALKVEEFITHRRPFKEINQAFEDLHNGDCLRTVLKSDEIK"
gene complement(160995..163154)
/gene="NRP1"
/locus_tag="YDL167C"
/db_xref="GeneID:851387"
mRNA complement(160995..163154)
/gene="NRP1"
/locus_tag="YDL167C"
/product="Nrp1p"
/transcript_id="NM_001180227.1"
/db_xref="GI:296143202"
/db_xref="GeneID:851387"
CDS complement(160995..163154)
/gene="NRP1"
/locus_tag="YDL167C"
/note="Putative RNA binding hypothetical protein;
localizes to stress granules induced by glucose
deprivation; predicted to be involved in ribosome
biogenesis"
/codon_start=1
/product="Nrp1p"
/protein_id="NP_010114.1"
/db_xref="GI:6320034"
/db_xref="SGD:S000002326"
/db_xref="GeneID:851387"
/translation="MHYVVLELQVAHLPDTPKDQCRIANIAFQIVNAETLVCHYGTNS
LPSIEVNGTTKSLESAMVQLDKDIHDVIGNDDFVLVSLYSTWHIRVTLPRQARDDGFI
LTSYLQHPKVFDLWKEFDRWCVNHPEILGQKKAISNNNCNTKSISINAAKNTKDLDEI
VRILEVSIPTEEAGSVPEIYSLLKRTTDILIQLHKKCTSPEDMESVLTKPYDSHTDIR
AFLQEKSKILYMNNLPPDTTQSELESWFTQYGVRPVGFWTVKNIVEDTSNVNNNWSLN
NSPYVEDQDSISGFVVFQTHEEATEVLALNGRSILSNLANTKQPRVVEHVLELQPSST
GVLDKAQEILSPFPQSKNKPRPGDWNCPSCGFSNFQRRTACFRCSFPAPSNSQIHTAN
SNNNVNSSRNNLNNRVNSGSSSNISNTAANHPYGAPEFNMIANNTPAALTYNRAHFPA
ITPLSRQNSLNMAPSNSGSPIIIADHFSGNNNIAPNYRYNNNINNNNNNINNMTNNRY
NINNNINGNGNGNGNNSNNNNNHNNNHNNNHHNGSINSNSNTNNNNNNNNGNNSNNCN
SNIGMGGCGSNMPFRAGDWKCSTCTYHNFAKNVVCLRCGGPKSISGDASETNHYIDSS
TFGPASRTPSNNNISVNTNGGSNAGRTDGNDNKGRDISLMEFMSPPLSMATKSMKEGD
GNGSSFNEFKSDKANVNFSNVGDNSAFGNGFNSSIRW"
gene complement(163449..164042)
/gene="FAP7"
/locus_tag="YDL166C"
/db_xref="GeneID:851388"
mRNA complement(163449..164042)
/gene="FAP7"
/locus_tag="YDL166C"
/product="Fap7p"
/transcript_id="NM_001180226.1"
/db_xref="GI:296143203"
/db_xref="GeneID:851388"
CDS complement(163449..164042)
/gene="FAP7"
/locus_tag="YDL166C"
/note="Essential NTPase required for small ribosome
subunit synthesis, mediates processing of the 20S pre-rRNA
at site D in the cytoplasm but associates only transiently
with 43S preribosomes via Rps14p, may be the endonuclease
for site D"
/codon_start=1
/product="Fap7p"
/protein_id="NP_010115.1"
/db_xref="GI:6320035"
/db_xref="SGD:S000002325"
/db_xref="GeneID:851388"
/translation="MEARRYGPNIIVTGTPGCGKSSTCEFLKNKLKDYKYYNISDFAK
DNDCFEGYDEGRKSHIVDEDKLLDMLEPLLRQGNSIVDWHVNDVFPERLIDLVVVLRC
DNSNLYSRLHARGYHDSKIEENLDAEIMGVVKQDAVESYEPHIVVELQSDTKEDMVSN
VSRIVAWEKMWLEQHPDGVTNEYQGPRSDDEDDEDSE"
gene 164290..164865
/gene="CDC36"
/locus_tag="YDL165W"
/gene_synonym="DNA19; NOT2"
/db_xref="GeneID:851389"
mRNA 164290..164865
/gene="CDC36"
/locus_tag="YDL165W"
/gene_synonym="DNA19; NOT2"
/product="CCR4-NOT core subunit CDC36"
/transcript_id="NM_001180225.1"
/db_xref="GI:296143204"
/db_xref="GeneID:851389"
CDS 164290..164865
/gene="CDC36"
/locus_tag="YDL165W"
/gene_synonym="DNA19; NOT2"
/note="Component of the CCR4-NOT complex, which has
multiple roles in regulating mRNA levels including
regulation of transcription and destabilizing mRNAs by
deadenylation; basal transcription factor"
/codon_start=1
/product="CCR4-NOT core subunit CDC36"
/protein_id="NP_010116.1"
/db_xref="GI:6320036"
/db_xref="SGD:S000002324"
/db_xref="GeneID:851389"
/translation="MEKFGLKALVPLLKLEDKELSSTYDHSMTLGADLSSMLYSLGIP
RDSQDHRVLDTFQSPWAETSRSEVEPRFFTPESFTNIPGVLQSTVTPPCFNSIQNDQQ
RVALFQDETLFFLFYKHPGTVIQELTYLELRKRNWRYHKTLKAWLTKDPMMEPIVSAD
GLSERGSYVFFDPQRWEKCQRDFLLFYNAIM"
gene complement(164987..167254)
/gene="CDC9"
/locus_tag="YDL164C"
/gene_synonym="MMS8"
/db_xref="GeneID:851391"
mRNA complement(164987..167254)
/gene="CDC9"
/locus_tag="YDL164C"
/gene_synonym="MMS8"
/product="Cdc9p"
/transcript_id="NM_001180224.1"
/db_xref="GI:296143205"
/db_xref="GeneID:851391"
CDS complement(164987..167254)
/gene="CDC9"
/locus_tag="YDL164C"
/gene_synonym="MMS8"
/EC_number="6.5.1.1"
/note="DNA ligase found in the nucleus and mitochondria,
an essential enzyme that joins Okazaki fragments during
DNA replication; also acts in nucleotide excision repair,
base excision repair, and recombination"
/codon_start=1
/product="DNA ligase (ATP) CDC9"
/protein_id="NP_010117.1"
/db_xref="GI:6320038"
/db_xref="SGD:S000002323"
/db_xref="GeneID:851391"
/translation="MRRLLTGCLLSSARPLKSRLPLLMSSSLPSSAGKKPKQATLARF
FTSMKNKPTEGTPSPKKSSKHMLEDRMDNVSGEEEYATKKLKQTAVTHTVAAPSSMGS
NFSSIPSSAPSSGVADSPQQSQRLVGEVEDALSSNNNDHYSSNIPYSEVCEVFNKIEA
ISSRLEIIRICSDFFIKIMKQSSKNLIPTTYLFINRLGPDYEAGLELGLGENLLMKTI
SETCGKSMSQIKLKYKDIGDLGEIAMGARNVQPTMFKPKPLTVGEVFKNLRAIAKTQG
KDSQLKKMKLIKRMLTACKGIEAKFLIRSLESKLRIGLAEKTVLISLSKALLLHDENR
EDSPDKDVPMDVLESAQQKIRDAFCQVPNYEIVINSCLEHGIMNLDKYCTLRPGIPLK
PMLAKPTKAINEVLDRFQGETFTSEYKYDGERAQVHLLNDGTMRIYSRNGENMTERYP
EINITDFIQDLDTTKNLILDCEAVAWDKDQGKILPFQVLSTRKRKDVELNDVKVKVCL
FAFDILCYNDERLINKSLKERREYLTKVTKVVPGEFQYATQITTNNLDELQKFLDESV
NHSCEGLMVKMLEGPESHYEPSKRSRNWLKLKKDYLEGVGDSLDLCVLGAYYGRGKRT
GTYGGFLLGCYNQDTGEFETCCKIGTGFSDEMLQLLHDRLTPTIIDGPKATFVFDSSA
EPDVWFEPTTLFEVLTADLSLSPIYKAGSATFDKGVSLRFPRFLRIREDKGVEDATSS
DQIVELYENQSHMQN"
gene 167714..169078
/gene="ENT1"
/locus_tag="YDL161W"
/db_xref="GeneID:851392"
mRNA 167714..169078
/gene="ENT1"
/locus_tag="YDL161W"
/product="Ent1p"
/transcript_id="NM_001180221.1"
/db_xref="GI:296143206"
/db_xref="GeneID:851392"
CDS 167714..169078
/gene="ENT1"
/locus_tag="YDL161W"
/note="Epsin-like protein involved in endocytosis and
actin patch assembly; functionally redundant with Ent2p;
binds clathrin via a clathrin-binding domain motif at
C-terminus; relocalizes from bud neck to cytoplasm upon
DNA replication stress"
/codon_start=1
/product="Ent1p"
/protein_id="NP_010120.1"
/db_xref="GI:6320039"
/db_xref="SGD:S000002320"
/db_xref="GeneID:851392"
/translation="MSKQFVRSAKNLVKGYSSTQVLVRNATSNDNHQVSKDSLIELAE
KSYDSADFFEIMDMLDKRLNDKGKYWRHIAKALTVIDYLIRFGSENCVLWCRENLYII
KTLKEFRHEDDEGIDQGQIVRVKAKELTALLSDDERLNEERNMNIKGRNRKGRRRRGT
GRSDENDDDLQRAISASRLTAEEDERRRKQDEDYETALQLSKEEEELKRLQDLQRMQQ
QQGQQQLQQPMYYDIFGNPITPEEYAQFQLQQQQQQQQQQLQQQPMYYDVFGNPITPE
ELAQFQQQQQLQEQQYLASMQQQQQAMSNNPFAKSEQSSSSPKRNQLVAASSPQQLQQ
QKQQEPLIQNRTGNQSMTDKYSKLNELLATGTGIDTFGNVGEARIPAQHTKTGTFINS
QGTGYRQVSDDPNHNPFLNSQYTGLPSTSVVPTQTGYGFGNQSQQQSQNNGSNNRGYT
LIDL"
gene complement(169366..169608)
/gene="MHF2"
/locus_tag="YDL160C-A"
/db_xref="GeneID:1466431"
mRNA complement(169366..169608)
/gene="MHF2"
/locus_tag="YDL160C-A"
/product="Mhf2p"
/transcript_id="NM_001184530.1"
/db_xref="GI:296143207"
/db_xref="GeneID:1466431"
CDS complement(169366..169608)
/gene="MHF2"
/locus_tag="YDL160C-A"
/note="Component of the heterotetrameric MHF histone-fold
complex; in humans the MMF complex interacts with both DNA
and Mph1p ortholog FANCM to stabilize and remodel blocked
replication forks and repair damaged DNA; mhf2 srs2 double
mutants are MMS hypersensitive; orthologous to human
centromere constitutive-associated network (CCAN) subunit
CENP-X, also known as MHF2"
/codon_start=1
/product="Mhf2p"
/protein_id="NP_878060.1"
/db_xref="GI:33438778"
/db_xref="SGD:S000028520"
/db_xref="GeneID:1466431"
/translation="MLSKEALIKILSQNEGGNDMKIADEVVPMIQKYLDIFIDEAVLR
SLQSHKDINGERGDKSPLELSHQDLERIVGLLLMDM"
gene complement(170410..171930)
/gene="DHH1"
/locus_tag="YDL160C"
/db_xref="GeneID:851394"
mRNA complement(170410..171930)
/gene="DHH1"
/locus_tag="YDL160C"
/product="Dhh1p"
/transcript_id="NM_001180220.1"
/db_xref="GI:296143208"
/db_xref="GeneID:851394"
CDS complement(170410..171930)
/gene="DHH1"
/locus_tag="YDL160C"
/EC_number="3.6.1.-"
/note="Cytoplasmic DExD/H-box helicase, stimulates mRNA
decapping; coordinates distinct steps in mRNA function and
decay, interacts with both the decapping and deadenylase
complexes, may have a role in mRNA export and translation;
C-terminus of Dhh1p interacts with Ngr1p and promotes
POR1, but not EDC1 mRNA decay; forms cytoplasmic foci upon
DNA replication stress"
/codon_start=1
/product="Dhh1p"
/protein_id="NP_010121.1"
/db_xref="GI:6320041"
/db_xref="SGD:S000002319"
/db_xref="GeneID:851394"
/translation="MGSINNNFNTNNNSNTDLDRDWKTALNIPKKDTRPQTDDVLNTK
GNTFEDFYLKRELLMGIFEAGFEKPSPIQEEAIPVAITGRDILARAKNGTGKTAAFVI
PTLEKVKPKLNKIQALIMVPTRELALQTSQVVRTLGKHCGISCMVTTGGTNLRDDILR
LNETVHILVGTPGRVLDLASRKVADLSDCSLFIMDEADKMLSRDFKTIIEQILSFLPP
THQSLLFSATFPLTVKEFMVKHLHKPYEINLMEELTLKGITQYYAFVEERQKLHCLNT
LFSKLQINQAIIFCNSTNRVELLAKKITDLGYSCYYSHARMKQQERNKVFHEFRQGKV
RTLVCSDLLTRGIDIQAVNVVINFDFPKTAETYLHRIGRSGRFGHLGLAINLINWNDR
FNLYKIEQELGTEIAAIPATIDKSLYVAENDETVPVPFPIEQQSYHQQAIPQQQLPSQ
QQFAIPPQQHHPQFMVPPSHQQQQAYPPPQMPSQQGYPPQQEHFMAMPPGQSQPQY"
gene 172182..172313
/locus_tag="YDL159W-A"
/gene_synonym="YDL159W-B"
/db_xref="GeneID:851395"
mRNA 172182..172313
/locus_tag="YDL159W-A"
/gene_synonym="YDL159W-B"
/product="hypothetical protein"
/transcript_id="NM_001184465.1"
/db_xref="GI:296143209"
/db_xref="GeneID:851395"
CDS 172182..172313
/locus_tag="YDL159W-A"
/gene_synonym="YDL159W-B"
/note="hypothetical protein; identified by sequence
comparison with hemiascomycetous yeast species"
/codon_start=1
/product="hypothetical protein"
/protein_id="NP_076884.1"
/db_xref="GI:13129162"
/db_xref="SGD:S000007599"
/db_xref="GeneID:851395"
/translation="MYNQIINTFIDDCLFLQTPMLQSPISSKIVLSFFLRNFFPSLF"
gene 172481..174028
/gene="STE7"
/locus_tag="YDL159W"
/db_xref="GeneID:851396"
mRNA 172481..174028
/gene="STE7"
/locus_tag="YDL159W"
/product="Ste7p"
/transcript_id="NM_001180219.1"
/db_xref="GI:296143210"
/db_xref="GeneID:851396"
CDS 172481..174028
/gene="STE7"
/locus_tag="YDL159W"
/EC_number="2.7.12.2"
/note="Signal transducing MAP kinase kinase involved in
pheromone response, where it phosphorylates Fus3p, and in
the pseudohyphal/invasive growth pathway, through
phosphorylation of Kss1p; phosphorylated by Ste11p,
degraded by ubiquitin pathway"
/codon_start=1
/product="Ste7p"
/protein_id="NP_010122.1"
/db_xref="GI:6320042"
/db_xref="SGD:S000002318"
/db_xref="GeneID:851396"
/translation="MFQRKTLQRRNLKGLNLNLHPDVGNNGQLQEKTETHQGQSRIEG
HVMSNINAIQNNSNLFLRRGIKKKLTLDAFGDDQAISKPNTVVIQQPQNEPVLVLSSL
SQSPCVSSSSSLSTPCIIDAYSNNFGLSPSSTNSTPSTIQGLSNIATPVENEHSISLP
PLEESLSPAAADLKDTLSGTSNGNYIQLQDLVQLGKIGAGNSGTVVKALHVPDSKIVA
KKTIPVEQNNSTIINQLVRELSIVKNVKPHENIITFYGAYYNQHINNEIIILMEYSDC
GSLDKILSVYKRFVQRGTVSSKKTWFNELTISKIAYGVLNGLDHLYRQYKIIHRDIKP
SNVLINSKGQIKLCDFGVSKKLINSIADTFVGTSTYMSPERIQGNVYSIKGDVWSLGL
MIIELVTGEFPLGGHNDTPDGILDLLQRIVNEPSPRLPKDRIYSKEMTDFVNRCCIKN
ERERSSIHELLHHDLIMKYVSPSKDDKFRHWCRKIKSKIKEDKRIKREALDRAKLEKK
QSERSTH"
gene complement(174232..174588)
/locus_tag="YDL157C"
/db_xref="GeneID:851398"
mRNA complement(174232..174588)
/locus_tag="YDL157C"
/product="hypothetical protein"
/transcript_id="NM_001180217.1"
/db_xref="GI:296143211"
/db_xref="GeneID:851398"
CDS complement(174232..174588)
/locus_tag="YDL157C"
/note="hypothetical protein; the authentic, non-tagged
protein is detected in highly purified mitochondria in
high-throughput studies"
/codon_start=1
/product="hypothetical protein"
/protein_id="NP_010124.1"
/db_xref="GI:6320044"
/db_xref="SGD:S000002316"
/db_xref="GeneID:851398"
/translation="MSNILAVFNPPPQRELEKEETMDCVPCQVMSTMFSVGFGSYLAS
GKPFKYGKKEAKRGISLTEFEKRNPQWWKVTLRSFGGLLIAFGFVRGTEGWLWHKNKE
YKNYKKLSNDGETQAN"
gene 174918..176486
/gene="CMR1"
/locus_tag="YDL156W"
/db_xref="GeneID:851399"
mRNA 174918..176486
/gene="CMR1"
/locus_tag="YDL156W"
/product="Cmr1p"
/transcript_id="NM_001180216.1"
/db_xref="GI:296143212"
/db_xref="GeneID:851399"
CDS 174918..176486
/gene="CMR1"
/locus_tag="YDL156W"
/note="DNA-binding protein with preference for UV-damaged
DNA; protein sequence contains three WD domains (WD-40
repeat); green fluorescent protein (GFP)-fusion protein
localizes to the cytoplasm and nucleus; potential
regulatory target of Mbp1p, which binds to the promoter
region; co-localizes with Hos2p in nuclear foci in
response to DNA damage by MMS"
/codon_start=1
/product="Cmr1p"
/protein_id="NP_010125.1"
/db_xref="GI:6320045"
/db_xref="SGD:S000002315"
/db_xref="GeneID:851399"
/translation="MPELTEFQKKRLENIKRNNDLLKKLHLSGVASQIKHEAGVLEKS
RAPAKKKQKTTNTRATKSASPTLPTRRSRRLRGESADDVKGIPNVNDNQLLKMGSPDG
QDKNFIDAIKEKPVIGDVKLSDLIKDEDESALLEKFKRFNNGNFSSGDFFEEIKKRQG
DVTGMDEFDLDLYDVFQPNEIKITYERISATYFHPAMEKKLIIAGDTSGTVGFWNVRD
EPLADSEEDRMEEPDITRVKLFTKNVGRIDCFPADTSKILLTSYDGSIRSVHLNNLQS
EEVLTLKNEYDDSLGISDCQFSYENPNVLFLTTLGGEFTTFDTRVKKSEYNLRRLADK
KIGSMAINPMRPYEIATGSLDRTLKIWDTRNLVKKPEWSQYEDYPSHEIVSTYDSRLS
VSAVSYSPTDGTLVCNGYDDTIRLFDVKSRDHLSAKLEPKLTIQHNCQTGRWTSILKA
RFKPNKNVFAIANMKRAIDIYNSEGQQLAHLPTATVPAVISWHPLRNWIAGGNSSGKI
FLFTDDSGTIKQEE"
gene 176773..178056
/gene="CLB3"
/locus_tag="YDL155W"
/db_xref="GeneID:851400"
mRNA 176773..178056
/gene="CLB3"
/locus_tag="YDL155W"
/product="Clb3p"
/transcript_id="NM_001180215.1"
/db_xref="GI:296143213"
/db_xref="GeneID:851400"
CDS 176773..178056
/gene="CLB3"
/locus_tag="YDL155W"
/note="B-type cyclin involved in cell cycle progression;
activates Cdc28p to promote the G2/M transition; may be
involved in DNA replication and spindle assembly;
accumulates during S phase and G2, then targeted for
ubiquitin-mediated degradation; relative distribution to
the nucleus increases upon DNA replication stress"
/codon_start=1
/product="Clb3p"
/protein_id="NP_010126.1"
/db_xref="GI:6320046"
/db_xref="SGD:S000002314"
/db_xref="GeneID:851400"
/translation="MHHNSQSLSSGHIRSPEDENVAPIGNLKHRTGSLSHISSAHPRV
ALSDVTNIVATNSSNNSISKPKVAPIKERLDSAAIIEEERLDANSVAQRKEADHNDLL
TDREQEEPVEDDGESEEDEEEDQEPLLLQHYASDTLVWEHAFRTYYRTTLDPNDDDVY
DVVMVAELSNEIFEYMRKLEDLYKPNPYYMDKQPELRWSFRSTLIDWIVQVHEKFQLL
PETLYLCINIIDRYLCKEVVPVNKFQLVGAASLFIAAKYEEINCPTIKDFVYMSENCY
SRNDLLDAERTILNGLEFELGWPGPMSFLRRISKADDYEHDTRTLAKYLLESTIMDHR
LVSAQPSWLAAGAYFLSKIILGQNQWSLAHVYYSNYTQEQILPLATIILENCRYASKR
HNAIWRKYSSRRYLHSSQIVAKWIALAEHRVERSN"
gene 178334..181039
/gene="MSH5"
/locus_tag="YDL154W"
/db_xref="GeneID:851401"
mRNA 178334..181039
/gene="MSH5"
/locus_tag="YDL154W"
/product="MutS family protein MSH5"
/transcript_id="NM_001180214.1"
/db_xref="GI:296143214"
/db_xref="GeneID:851401"
CDS 178334..181039
/gene="MSH5"
/locus_tag="YDL154W"
/note="Protein of the MutS family, forms a dimer with
Msh4p that facilitates crossovers between homologs during
meiosis; msh5-Y823H mutation confers tolerance to DNA
alkylating agents; homologs present in C. elegans and
humans"
/codon_start=1
/product="MutS family protein MSH5"
/protein_id="NP_010127.1"
/db_xref="GI:6320047"
/db_xref="SGD:S000002313"
/db_xref="GeneID:851401"
/translation="MSHEWLISASETMRSIGNGEGLRDKGAVVANNDGEFNEGDTNRE
EDSSTIFSFDFDEEIVMCIDFSGGKLGCSILDYHTKTLKAFDQDYVVNKTTISSHDLI
DDADMSSNDISLLLGLLIMEANPTVCLVPARLEDWIFDYIKTKCDEINCRLELQPIKR
FKKWDLLQSLQLRGHDNQTILNDILSNSKFTTTVTLGTVGCILANHEQLGEYNDSTAS
SNMVTGRLVQNAFEDVIHGIRYIDIRDRMVLDENTISALHIFPTAHKLGHDKMMRNGF
FSVFELFNQVSSDYARRILKSWLINPLTNKKRIETRYSIIRTLLDKQNAIIFSDLSQS
IKRCPDAFGFINQLRSGKSTLGTWSKVASFLEKGIAIFQLVSSLKLGSDEANILHDIK
NKVDISALKECLRKVETVIDFDTSRDTKTLTINTGVDNRLDECRNIYNHLEGILLDVA
RETQIFLLNTMPQEDCKTTKSLEKLVNAVYIPQLGYLVTISVLMEPLLDGIPNLQWEE
IFRSSENIYFKNGRVLELDETYGDIYGAISDFEIEILFSLQEQILRRKTQLTAYNILL
SELEILLSFAQVSAERNYAEPQLVEDECILEIINGRHALYETFLDNYIPNSTMIDGGL
FSELSWCEQNKGRIIVVTGANASGKSVYLTQNGLIVYLAQIGCFVPAERARIGIADKI
LTRIRTQETVYKTQSSFLLDSQQMAKSLSLATEKSLILIDEYGKGTDILDGPSLFGSI
MLNMSKSEKCPRIIACTHFHELFNENVLTENIKGIKHYCTDILISQKYNLLETAHVGE
DHESEGITFLFKVKEGISKQSFGIYCAKVCGLSRDIVERAEELSRMINRGDDVVQQCG
NLTEKEMREFQKNQEIVKKFLSWDLDLETTTTSENLRLKLKNFLR"
gene complement(181186..183018)
/gene="SAS10"
/locus_tag="YDL153C"
/gene_synonym="UTP3"
/db_xref="GeneID:851403"
mRNA complement(181186..183018)
/gene="SAS10"
/locus_tag="YDL153C"
/gene_synonym="UTP3"
/product="Sas10p"
/transcript_id="NM_001180213.1"
/db_xref="GI:296143215"
/db_xref="GeneID:851403"
CDS complement(181186..183018)
/gene="SAS10"
/locus_tag="YDL153C"
/gene_synonym="UTP3"
/note="Essential subunit of U3-containing Small Subunit
(SSU) processome complex involved in production of 18S
rRNA and assembly of small ribosomal subunit; disrupts
silencing when overproduced; mutant has increased
aneuploidy tolerance"
/codon_start=1
/product="Sas10p"
/protein_id="NP_010128.1"
/db_xref="GI:6320049"
/db_xref="SGD:S000002312"
/db_xref="GeneID:851403"
/translation="MVRKGSNRTKTSEVGDEINPYGLNEVDDFASKREKVLLGQSTFG
DSNKDDDHSLLEDEDEEEVLAMDEDDESIDEREDEEEEEEEELDGAAAYKKIFGRNLE
TDQLPEEDEENGMLDNENAWGSTKGEYYGADDLDDDEAAKEIEKEALRQQKKHLEELN
MNDYLDEEEEEEWVKSAKEFDMGEFKNSTKQADTKTSITDILNMDDEARDNYLRTMFP
EFAPLSKEFTELAPKFDELKKSEENEFNKLKLIALGSYLGTISCYYSILLHELHNNED
FTSMKGHPVMEKILTTKEIWRQASELPSSFDVNEGDGSESEETANIEAFNEKKLNELQ
NSEDSDAEDGGKQKQEIDEEERESDEEEEEEDVDIDDFEEYVAQSRLHSKPKTSSMPE
ADDFIESEIADVDAQDKKARRRTLRFYTSKIDQQENKKTDRFKGDDDIPYKERLFERQ
QRLLDEARKRGMHDNNGADLDDKDYGSEDEAVSRSINTQGENDYYQQVQRGKQDKKIS
RKEAHKNAVIAAREGKLAELAENVSGDGKRAINYQILKNKGLTPKRNKDNRNSRVKKR
KKYQKAQKKLKSVRAVYSGGQSGVYEGEKTGIKKGLTRSVKFKN"
gene 183343..184611
/gene="RPC53"
/locus_tag="YDL150W"
/gene_synonym="RPC4"
/db_xref="GeneID:851404"
mRNA 183343..184611
/gene="RPC53"
/locus_tag="YDL150W"
/gene_synonym="RPC4"
/product="Rpc53p"
/transcript_id="NM_001180210.1"
/db_xref="GI:296143216"
/db_xref="GeneID:851404"
CDS 183343..184611
/gene="RPC53"
/locus_tag="YDL150W"
/gene_synonym="RPC4"
/note="RNA polymerase III subunit C53"
/codon_start=1
/product="Rpc53p"
/protein_id="NP_010131.1"
/db_xref="GI:6320050"
/db_xref="SGD:S000002309"
/db_xref="GeneID:851404"
/translation="MSSNKGNGRLPSLKDSSSNGGGSAKPSLKFKPKAVARKSKEERE
AAASKVKLEEESKRGNDKKHFNNKNKRVTGAGGQQRRMAKYLNNTHVISSGPLAAGNF
VSEKGDLRRGFIKSEGSGSSLVQKGLETIDNGAESSENEAEDDDNEGVASKSKKKFNM
GKEFEARNLIEDEDDGESEKSSDVDMDDEEWRSKRIEQLFPVRPVRVRHEDVETVKRE
IQEALSEKPTREPTPSVKTEPVGTGLQSYLEERERQVNEKLADLGLEKEFQSVDGKEA
AAELELLNADHQHILRKLKKMNNKPERFMVFQLPTRLPAFERPAVKEEKEDMETQASD
PSKKKKNIKKKDTKDALSTRELAGKVGSIRVHKSGKLSVKIGNVVMDIGKGAETTFLQ
DVIALSIADDASSAELLGRVDGKIVVTPQI"
gene 184925..187918
/gene="ATG9"
/locus_tag="YDL149W"
/gene_synonym="APG9; AUT9; CVT7"
/db_xref="GeneID:851406"
mRNA 184925..187918
/gene="ATG9"
/locus_tag="YDL149W"
/gene_synonym="APG9; AUT9; CVT7"
/product="Atg9p"
/transcript_id="NM_001180209.1"
/db_xref="GI:296143217"
/db_xref="GeneID:851406"
CDS 184925..187918
/gene="ATG9"
/locus_tag="YDL149W"
/gene_synonym="APG9; AUT9; CVT7"
/note="Transmembrane protein involved in forming Cvt and
autophagic vesicles; cycles between the phagophore
assembly site (PAS) and other cytosolic punctate
structures, not found in autophagosomes; may be involved
in membrane delivery to the PAS"
/codon_start=1
/product="Atg9p"
/protein_id="NP_010132.1"
/db_xref="GI:6320052"
/db_xref="SGD:S000002308"
/db_xref="GeneID:851406"
/translation="MERDEYQLPNSHGKNTFLSRIFGLQSDEVNPSLNSQEMSNFPLP
DIERGSSLLHSTNDSREDVDENDLRVPESDQGTSTEEEDEVDEEQVQAYAPQISDGLD
GDHQLNSVTSKENVLETEKSNLERLVEGSTDDSVPKVGQLSSEEEEDNEFINNDGFDD
DTPLFQKSKIHEFSSKKSNTIEDGKRPLFFRHILQNNRPQRDTQKLFTSSNAIHHDKD
KSANNGPRNINGNQKHGTKYFGSATQPRFTGSPLNNTNRFTKLFPLRKPNLLSNISVL
NNTPEDRINTLSVKERALWKWANVENLDIFLQDVYNYYLGNGFYCIILEKILNICTLL
FVVFVSTYMGHCVDYSKLPTSHRVSDIIIDKCYSNSITGFTKFFLWMFYFFVILKIVQ
LYFDVQKLSELQNFYKYLLNISDDELQTLPWQNVIQQLMYLKDQNAMTANVVEVKAKN
RIDAHDVANRIMRRENYLIALYNSDILNLSLPIPLFRTNVLTKTLEWNINLCVMGFVF
NESGFIKQSILKPSQREFTREELQKRFMLAGFLNIILAPFLVTYFVLLYFFRYFNEYK
TSPGSIGARQYTPIAEWKFREYNELYHIFKKRISLSTTLANKYVDQFPKEKTNLFLKF
VSFICGSFVAILAFLTVFDPENFLNFEITSDRSVIFYITILGAIWSVSRNTITQEYHV
FDPEETLKELYEYTHYLPKEWEGRYHKEEIKLEFCKLYNLRIVILLRELTSLMITPFV
LWFSLPSSAGRIVDFFRENSEYVDGLGYVCKYAMFNMKNIDGEDTHSMDEDSLTKKIA
VNGSHTLNSKRRSKFTAEDHSDKDLANNKMLQSYVYFMDDYSNSENLTGKYQLPAKKG
YPNNEGDSFLNNKYSWRKQFQPGQKPELFRIGKHALGPGHNISPAIYSTRNPGKNWDN
NNNGDDIKNGTNNATAKNDDNNGNNDHEYVLTESFLDSGAFPNHDVIDHNKMLNSNYN
GNGILNKGGVLGLVKEYYKKSDVGR"
gene complement(188154..190586)
/gene="NOP14"
/locus_tag="YDL148C"
/gene_synonym="UTP2"
/db_xref="GeneID:851407"
mRNA complement(188154..190586)
/gene="NOP14"
/locus_tag="YDL148C"
/gene_synonym="UTP2"
/product="Nop14p"
/transcript_id="NM_001180208.1"
/db_xref="GI:296143218"
/db_xref="GeneID:851407"
CDS complement(188154..190586)
/gene="NOP14"
/locus_tag="YDL148C"
/gene_synonym="UTP2"
/note="Nucleolar protein, forms a complex with Noc4p that
mediates maturation and nuclear export of 40S ribosomal
subunits; also present in the small subunit processome
complex, which is required for processing of pre-18S rRNA"
/codon_start=1
/product="Nop14p"
/protein_id="NP_010133.1"
/db_xref="GI:6320053"
/db_xref="SGD:S000002307"
/db_xref="GeneID:851407"
/translation="MAGSQLKNLKAALKARGLTGQTNVKSKNKKNSKRQAKEYDREEK
KKAIAEIREEFNPFEIKAARNKRRDGLPSKTADRIAVGKPGISKQIGEEQRKRAFEAR
KMMKNKRGGVIDKRFGERDKLLTEEEKMLERFTRERQSQSKRNANLFNLEDDEDDGDM
FGDGLTHLGQSLSLEDELANDEEDFLASKRFNEDDAELQQPQRKKTKAEVMKEVIAKS
KFYKQERQKAQGIMEDQIDNLDDNFEDVMSELMMTQPKKNPMEPKTDLDKEYDIKVKE
LQLDKRAAPSDRTKTEEEKNAEAEEKKRELEQQRLDRMNGMIELEEGEERGVEDLDDG
FWENEEDYEDDNDGIADSDDDIKFEDQGRDEGFSQILKKKNISISCPRTHDALLDQVK
KLDLDDHPKIVKNIIKAYQPKLAEGNKEKLGKFTAVLLRHIIFLSNQNYLKNVQSFKR
TQNALISILKSLSEKYNRELSEECRDYINEMQARYKKNHFDALSNGDLVFFSIIGILF
STSDQYHLVITPALILMSQFLEQIKFNSLKRIAFGAVLVRIVSQYQRISKRYIPEVVY
FFQKILLTFIVEKENQEKPLDFENIRLDSYELGLPLDVDFTKKRSTIIPLHTLSTMDT
EAHPVDQCVSVLLNVMESLDATISTVWKSLPAFNEIILPIQQLLSAYTSKYSDFEKPR
NILNKVEKLTKFTEHIPLALQNHKPVSIPTHAPKYEENFNPDKKSYDPDRTRSEINKM
KAQLKKERKFTMKEIRKDAKFEARQRIEEKNKESSDYHAKMAHIVNTINTEEGAEKNK
YERERKLRGGKK"
gene 190924..192261
/gene="RPN5"
/locus_tag="YDL147W"
/gene_synonym="NAS5"
/db_xref="GeneID:851408"
mRNA 190924..192261
/gene="RPN5"
/locus_tag="YDL147W"
/gene_synonym="NAS5"
/product="proteasome regulatory particle lid subunit RPN5"
/transcript_id="NM_001180207.1"
/db_xref="GI:296143219"
/db_xref="GeneID:851408"
CDS 190924..192261
/gene="RPN5"
/locus_tag="YDL147W"
/gene_synonym="NAS5"
/note="Subunit of the COP9 signalosome (CSN) and
non-ATPase regulatory subunit of the 26S proteasome lid,
similar to mammalian p55 subunit and to another S.
cerevisiae regulatory subunit, Rpn7p; Rpn5p is an
essential protein"
/codon_start=1
/product="proteasome regulatory particle lid subunit RPN5"
/protein_id="NP_010134.1"
/db_xref="GI:6320054"
/db_xref="SGD:S000002306"
/db_xref="GeneID:851408"
/translation="MSRDAPIKADKDYSQILKEEFPKIDSLAQNDCNSALDQLLVLEK
KTRQASDLASSKEVLAKIVDLLASRNKWDDLNEQLTLLSKKHGQLKLSIQYMIQKVME
YLKSSKSLDLNTRISVIETIRVVTENKIFVEVERARVTKDLVEIKKEEGKIDEAADIL
CELQVETYGSMEMSEKIQFILEQMELSILKGDYSQATVLSRKILKKTFKNPKYESLKL
EYYNLLVKISLHKREYLEVAQYLQEIYQTDAIKSDEAKWKPVLSHIVYFLVLSPYGNL
QNDLIHKIQNDNNLKKLESQESLVKLFTTNELMRWPIVQKTYEPVLNEDDLAFGGEAN
KHHWEDLQKRVIEHNLRVISEYYSRITLLRLNELLDLTESQTETYISDLVNQGIIYAK
VNRPAKIVNFEKPKNSSQLLNEWSHNVDELLEHIETIGHLITKEEIMHGLQAK"
gene 192750..194225
/gene="LDB17"
/locus_tag="YDL146W"
/db_xref="GeneID:851409"
mRNA 192750..194225
/gene="LDB17"
/locus_tag="YDL146W"
/product="Ldb17p"
/transcript_id="NM_001180206.1"
/db_xref="GI:296143220"
/db_xref="GeneID:851409"
CDS 192750..194225
/gene="LDB17"
/locus_tag="YDL146W"
/note="Protein involved in the regulation of endocytosis;
transiently recruited to actin cortical patches in a
SLA1-dependent manner after late coat component assembly;
GFP-fusion protein localizes to the periphery, cytoplasm,
bud, and bud neck"
/codon_start=1
/product="Ldb17p"
/protein_id="NP_010135.1"
/db_xref="GI:6320055"
/db_xref="SGD:S000002305"
/db_xref="GeneID:851409"
/translation="MILDPLSPNIENHTQDEIIEFWEKTESIANIPKENLDESHVNSS
LVAYLKFATDSYKVFINTDRDLYRMSLILLESSLFEFKKEFCLSKLQSLLNIDLLEMN
MKFIIVYILLCEAKKNVYSLEIMLKFQGFTVFYNTLYTQFAYLSKYGKERTVASKHQY
NSNNSSTGTSLDSLDRSLTDIDLGIIDEMKQISTVLMDLLFQIMKYCKCVIANLQIVD
DFFVYYMMESMRSDTMDDMFNNAEFKLLLALNEQYMMFAKEYDIENKVYKYLINGSVS
RCFTELLLLKFNRASDPPLQIMMCKIIYLILTPRGDYSPMNFFYTNDLRVLIDVLIRE
LQNISEDEEVLRNTLLRVLIPLLKNTQLSKTHYRKDDLNKLLNYLSTLDNICVDSPAL
HEHQVTVALSRKCLQQIPWLETPSTPSDGGSSVSSNNTSRNSSIVALGTPDNQNILAR
KGHLYSNRELDVSAESLTKRKAKAPPPPPPPPPSRKCGTPK"
gene complement(194571..198176)
/gene="COP1"
/locus_tag="YDL145C"
/gene_synonym="RET1; SEC33; SOO1"
/db_xref="GeneID:851410"
mRNA complement(194571..198176)
/gene="COP1"
/locus_tag="YDL145C"
/gene_synonym="RET1; SEC33; SOO1"
/product="Cop1p"
/transcript_id="NM_001180205.1"
/db_xref="GI:296143221"
/db_xref="GeneID:851410"
CDS complement(194571..198176)
/gene="COP1"
/locus_tag="YDL145C"
/gene_synonym="RET1; SEC33; SOO1"
/note="Alpha subunit of COPI vesicle coatomer complex,
which surrounds transport vesicles in the early secretory
pathway"
/codon_start=1
/product="Cop1p"
/protein_id="NP_010136.1"
/db_xref="GI:6320056"
/db_xref="SGD:S000002304"
/db_xref="GeneID:851410"
/translation="MKMLTKFESKSTRAKGIAFHPSRPWVLVALFSSTIQLWDYRMGT
LLHRFEDHEGPVRGLDFHPTQPIFVSAGDDYTIKVWSLDTNKCLYTLTGHLDYVRTVF
FHRELPWIISASDDQTIRIWNWQNRKEIACLTGHNHFVMCAQFHPTDDLIVSASLDET
IRIWDISGLRKRHSAPGTSSFEEQMSAQQNLLDGSLGDCVVKFILEGHTRGVNWASFH
PTLPLIVSGSDDRQVKLWRMSATKAWEVDTCRGHTNNVDSVIFHPHQNLIISVGEDKT
LRVWDLDKRTPVKQFKRENDRFWLIAAHPHINLFGAAHDSGIMVFKLDRERPCSFIHQ
NQLFFVNAEKQIQSFNFQKRVASLPYASLKGIGQPWDAFRSISYNPSQHSVLVNEANG
KFALVILPKQPVGAVEPTSVTQDTGNFATFVGRNRFVVYNKNTESVEVRSLENKVTRN
IKVEETVRTIVAAGPGSVLVIHPREVILYDVQQGKKVSQLAVKNVKYVSWSLDGQYVA
LMSKHTITLATKKLELINSMHETIRIKSAAWDETGVLIYSTLNHIRYSLLNGDRGIIK
TLEKTLYITKVQGKLVYCLNREGEIEILTIDPTEYRFKKALVNKNFPEVLRLIKDSNL
VGQNIISYLQKSGYPEIALQFVQDPHIRFDLALEYGNLDVALDEAKKLNDSSTWERLI
QEALAQGNASLAEMIYQTQHSFDKLSFLYLVTGDVNKLSKMQNIAQTREDFGSMLLNT
FYNNSTKERSSIFAEGGSLPLAYAVAKANGDEAAASAFLEQAEVDEQDVTLPDQMDAS
NFVQRPVISKPLEKWPLKEAELSYFEKAVLGQIDDLTIDDETPAVNTTQEQEEPLGEE
NFNDEDIGEDEGAWDLGDEDLDVGEELPEEVEQGEITSPAQEVETAIWIKNSKLPAVL
VAAGAFDAAVQALSKQVGVVKLEPLKKYFTNIYEGCRTYIPSTPCELPAQLGYVRAYD
DTVSEDQILPYVPGLDVVNEKMNEGYKNFKLNKPDIAIECFREAIYRITLLMVDDAED
EKLAHKILETAREYILGLSIELERRSLKEGNTVRMLELAAYFTKAKLSPIHRTNALQV
AMSQHFKHKNFLQASYFAGEFLKIISSGPRAEQARKIKNKADSMASDAIPIDFDPYAK
FDICAATYKPIYEDTPSVSDPLTGSKYVITEKDKIDRIAMISKIGAPASGLRIRV"
gene complement(198662..199732)
/locus_tag="YDL144C"
/db_xref="GeneID:851411"
mRNA complement(198662..199732)
/locus_tag="YDL144C"
/product="hypothetical protein"
/transcript_id="NM_001180204.1"
/db_xref="GI:296143222"
/db_xref="GeneID:851411"
CDS complement(198662..199732)
/locus_tag="YDL144C"
/note="hypothetical protein; green fluorescent protein
(GFP)-fusion protein localizes to the cytoplasm and
nucleus; YDL144C is not an essential gene; protein
abundance increases in response to DNA replication stress"
/codon_start=1
/product="hypothetical protein"
/protein_id="NP_010137.2"
/db_xref="GI:37362628"
/db_xref="SGD:S000002303"
/db_xref="GeneID:851411"
/translation="MSRILVIGAGGVGVITALSLWLKKESDVSLVVRSDYDRVLKHGY
TIESCDYGRLEGWRPHHIYSSVEDAASAADNQGYNYIVVTTKNIIDGPVNSRVSNIIR
PVLEKNKELHGPQLTTHILLVQNGIDIEKEIWAEFPREQYRYTVLSGIQLIGSTKIGS
GHISQVGQDHLSCGAFDPQDAAAIQAANDFVRMYSNEGQNFVEFDPRVRYSRWKKLLY
NAAINTSTALVGLDVPRCLEFGVNKKSTEIEVFHPAMREIIAIAASEGIIIEEEFITM
FTEITRKKVFKPSMCVDCEKGQLMELEVILGNPIRIAKRNGVATPTLSILYNLLVLVQ
AKLKERKGLLKFDEKTATLVDE"
gene 199996..201582
/gene="CCT4"
/locus_tag="YDL143W"
/gene_synonym="ANC2; TCP4"
/db_xref="GeneID:851412"
mRNA 199996..201582
/gene="CCT4"
/locus_tag="YDL143W"
/gene_synonym="ANC2; TCP4"
/product="Cct4p"
/transcript_id="NM_001180203.1"
/db_xref="GI:296143223"
/db_xref="GeneID:851412"
CDS 199996..201582
/gene="CCT4"
/locus_tag="YDL143W"
/gene_synonym="ANC2; TCP4"
/note="Subunit of the cytosolic chaperonin Cct ring
complex, related to Tcp1p, required for the assembly of
actin and tubulins in vivo"
/codon_start=1
/product="Cct4p"
/protein_id="NP_010138.1"
/db_xref="GI:6320058"
/db_xref="SGD:S000002302"
/db_xref="GeneID:851412"
/translation="MSAKVPSNATFKNKEKPQEVRKANIIAARSVADAIRTSLGPKGM
DKMIKTSRGEIIISNDGHTILKQMAILHPVARMLVEVSAAQDSEAGDGTTSVVILTGA
LLGAAERLLNKGIHPTIIADSFQSAAKRSVDILLEMCHKVSLSDREQLVRAASTSLSS
KIVSQYSSFLAPLAVDSVLKISDENSKNVDLNDIRLVKKVGGTIDDTEMIDGVVLTQT
AIKSAGGPTRKEKAKIGLIQFQISPPKPDTENNIIVNDYRQMDKILKEERAYLLNICK
KIKKAKCNVLLIQKSILRDAVNDLALHFLSKLNIMVVKDIEREEIEFLSKGLGCKPIA
DIELFTEDRLGSADLVEEIDSDGSKIVRVTGIRNNNARPTVSVVIRGANNMIIDETER
SLHDALCVIRCLVKERGLIAGGGAPEIEISRRLSKEARSMEGVQAFIWQEFASALEVI
PTTLAENAGLNSIKVVTELRSKHENGELNDGISVRRSGTTNTYEEHILQPVLVSTSAI
TLASECVKSILRIDDIAFSR"
gene complement(201719..202570)
/gene="CRD1"
/locus_tag="YDL142C"
/gene_synonym="CLS1"
/db_xref="GeneID:851413"
mRNA complement(201719..202570)
/gene="CRD1"
/locus_tag="YDL142C"
/gene_synonym="CLS1"
/product="cardiolipin synthase"
/transcript_id="NM_001180202.1"
/db_xref="GI:296143224"
/db_xref="GeneID:851413"
CDS complement(201719..202570)
/gene="CRD1"
/locus_tag="YDL142C"
/gene_synonym="CLS1"
/EC_number="2.7.8.-"
/note="Cardiolipin synthase; produces cardiolipin, which
is a phospholipid of the mitochondrial inner membrane that
is required for normal mitochondrial membrane potential
and function; also required for normal vacuolar ion
homeostasis"
/codon_start=1
/product="cardiolipin synthase"
/protein_id="NP_010139.1"
/db_xref="GI:6320059"
/db_xref="SGD:S000002301"
/db_xref="GeneID:851413"
/translation="MIQMVPIYSCSALLRRTIPKRPFYHVLSGLTVRFKVNPQLNYNL
FRDLTRREYATNPSKTPHIKSKLLNIPNILTLSRIGCTPFIGLFIITNNLTPALGLFA
FSSITDFMDGYIARKYGLKTIAGTILDPLADKLLMITTTLALSVPSGPQIIPVSIAAI
ILGRDVLLAISALFIRYSTLKLKYPGRVAWNSYWDIVRYPSAEVRPSQLSKWNTFFQM
VYLGSGVLLLLYEKEEGCEKTEEDFEDRKQDFQKAFSYLGYVTATTTIMSGVSYALKR
NAFKLLK"
gene 203039..205111
/gene="BPL1"
/locus_tag="YDL141W"
/gene_synonym="ACC2"
/db_xref="GeneID:851414"
mRNA 203039..205111
/gene="BPL1"
/locus_tag="YDL141W"
/gene_synonym="ACC2"
/product="biotin--[acetyl-CoA-carboxylase] ligase BPL1"
/transcript_id="NM_001180201.1"
/db_xref="GI:296143225"
/db_xref="GeneID:851414"
CDS 203039..205111
/gene="BPL1"
/locus_tag="YDL141W"
/gene_synonym="ACC2"
/EC_number="6.3.4.15"
/EC_number="6.3.4.-"
/note="Biotin:apoprotein ligase, covalently modifies
proteins with the addition of biotin, required for
acetyl-CoA carboxylase (Acc1p) holoenzyme formation"
/codon_start=1
/product="biotin--[acetyl-CoA-carboxylase] ligase BPL1"
/protein_id="NP_010140.1"
/db_xref="GI:6320060"
/db_xref="SGD:S000002300"
/db_xref="GeneID:851414"
/translation="MNVLVYNGPGTTPGSVKHAVESLRDFLEPYYAVSTVNVKVLQTE
PWMSKTSAVVFPGGADLPYVQACQPIISRLKHFVSKQGGVFIGFCAGGYFGTSRVEFA
QGDPTMEVSGSRDLRFFPGTSRGPAYNGFQYNSEAGARAVKLNLPDGSQFSTYFNGGA
VFVDADKFDNVEILATYAEHPDVPSSDSGKGQSENPAAVVLCTVGRGKVLLTGPHPEF
NVRFMRKSTDKHFLETVVENLKAQEIMRLKFMRTVLTKTGLNCNNDFNYVRAPNLTPL
FMASAPNKRNYLQEMENNLAHHGMHANNVELCSELNAETDSFQFYRGYRASYDAASSS
LLHKEPDEVPKTVIFPGVDEDIPPFQYTPNFDMKEYFKYLNVQNTIGSLLLYGEVVTS
TSTILNNNKSLLSSIPESTLLHVGTIQVSGRGRGGNTWINPKGVCASTAVVTMPLQSP
VTNRNISVVFVQYLSMLAYCKAILSYAPGFSDIPVRIKWPNDLYALSPTYYKRKNLKL
VNTGFEHTKLPLGDIEPAYLKISGLLVNTHFINNKYCLLLGCGINLTSDGPTTSLQTW
IDILNEERQQLHLDLLPAIKAEKLQALYMNNLEVILKQFINYGAAEILPSYYELWLHS
NQIVTLPDHGNTQAMITGITEDYGLLIAKELVSGSSTQFTGNVYNLQPDGNTFDIFKS
LIAKKVQS"
gene complement(205360..210561)
/gene="RPO21"
/locus_tag="YDL140C"
/gene_synonym="RPB1; RPB220; SUA8"
/db_xref="GeneID:851415"
mRNA complement(205360..210561)
/gene="RPO21"
/locus_tag="YDL140C"
/gene_synonym="RPB1; RPB220; SUA8"
/product="Rpo21p"
/transcript_id="NM_001180200.1"
/db_xref="GI:296143226"
/db_xref="GeneID:851415"
CDS complement(205360..210561)
/gene="RPO21"
/locus_tag="YDL140C"
/gene_synonym="RPB1; RPB220; SUA8"
/EC_number="2.7.7.6"
/note="RNA polymerase II largest subunit B220, part of
central core; phosphorylation of C-terminal heptapeptide
repeat domain regulates association with transcription and
splicing factors; similar to bacterial beta-prime"
/codon_start=1
/product="Rpo21p"
/protein_id="NP_010141.1"
/db_xref="GI:6320061"
/db_xref="SGD:S000002299"
/db_xref="GeneID:851415"
/translation="MVGQQYSSAPLRTVKEVQFGLFSPEEVRAISVAKIRFPETMDET
QTRAKIGGLNDPRLGSIDRNLKCQTCQEGMNECPGHFGHIDLAKPVFHVGFIAKIKKV
CECVCMHCGKLLLDEHNELMRQALAIKDSKKRFAAIWTLCKTKMVCETDVPSEDDPTQ
LVSRGGCGNTQPTIRKDGLKLVGSWKKDRATGDADEPELRVLSTEEILNIFKHISVKD
FTSLGFNEVFSRPEWMILTCLPVPPPPVRPSISFNESQRGEDDLTFKLADILKANISL
ETLEHNGAPHHAIEEAESLLQFHVATYMDNDIAGQPQALQKSGRPVKSIRARLKGKEG
RIRGNLMGKRVDFSARTVISGDPNLELDQVGVPKSIAKTLTYPEVVTPYNIDRLTQLV
RNGPNEHPGAKYVIRDSGDRIDLRYSKRAGDIQLQYGWKVERHIMDNDPVLFNRQPSL
HKMSMMAHRVKVIPYSTFRLNLSVTSPYNADFDGDEMNLHVPQSEETRAELSQLCAVP
LQIVSPQSNKPCMGIVQDTLCGIRKLTLRDTFIELDQVLNMLYWVPDWDGVIPTPAII
KPKPLWSGKQILSVAIPNGIHLQRFDEGTTLLSPKDNGMLIIDGQIIFGVVEKKTVGS
SNGGLIHVVTREKGPQVCAKLFGNIQKVVNFWLLHNGFSTGIGDTIADGPTMREITET
IAEAKKKVLDVTKEAQANLLTAKHGMTLRESFEDNVVRFLNEARDKAGRLAEVNLKDL
NNVKQMVMAGSKGSFINIAQMSACVGQQSVEGKRIAFGFVDRTLPHFSKDDYSPESKG
FVENSYLRGLTPQEFFFHAMGGREGLIDTAVKTAETGYIQRRLVKALEDIMVHYDNTT
RNSLGNVIQFIYGEDGMDAAHIEKQSLDTIGGSDAAFEKRYRVDLLNTDHTLDPSLLE
SGSEILGDLKLQVLLDEEYKQLVKDRKFLREVFVDGEANWPLPVNIRRIIQNAQQTFH
IDHTKPSDLTIKDIVLGVKDLQENLLVLRGKNEIIQNAQRDAVTLFCCLLRSRLATRR
VLQEYRLTKQAFDWVLSNIEAQFLRSVVHPGEMVGVLAAQSIGEPATQMTLNTFHFAG
VASKKVTSGVPRLKEILNVAKNMKTPSLTVYLEPGHAADQEQAKLIRSAIEHTTLKSV
TIASEIYYDPDPRSTVIPEDEEIIQLHFSLLDEEAEQSFDQQSPWLLRLELDRAAMND
KDLTMGQVGERIKQTFKNDLFVIWSEDNDEKLIIRCRVVRPKSLDAETEAEEDHMLKK
IENTMLENITLRGVENIERVVMMKYDRKVPSPTGEYVKEPEWVLETDGVNLSEVMTVP
GIDPTRIYTNSFIDIMEVLGIEAGRAALYKEVYNVIASDGSYVNYRHMALLVDVMTTQ
GGLTSVTRHGFNRSNTGALMRCSFEETVEILFEAGASAELDDCRGVSENVILGQMAPI
GTGAFDVMIDEESLVKYMPEQKITEIEDGQDGGVTPYSNESGLVNADLDVKDELMFSP
LVDSGSNDAMAGGFTAYGGADYGEATSPFGAYGEAPTSPGFGVSSPGFSPTSPTYSPT
SPAYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSP
SYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPAYSPTSPSY
SPTSPSYSPTSPSYSPTSPSYSPTSPNYSPTSPSYSPTSPGYSPGSPAYSPKQDEQKH
NENENSR"
gene complement(211375..212046)
/gene="SCM3"
/locus_tag="YDL139C"
/db_xref="GeneID:851416"
mRNA complement(211375..212046)
/gene="SCM3"
/locus_tag="YDL139C"
/product="Scm3p"
/transcript_id="NM_001180199.1"
/db_xref="GI:296143227"
/db_xref="GeneID:851416"
CDS complement(211375..212046)
/gene="SCM3"
/locus_tag="YDL139C"
/note="Nonhistone component of centromeric chromatin that
binds stoichiometrically to CenH3-H4 histones, required
for kinetochore assembly; required for G2/M progression
and localization of Cse4p; may protect Cse4p from
ubiquitylation"
/codon_start=1
/product="Scm3p"
/protein_id="NP_010142.2"
/db_xref="GI:37362629"
/db_xref="SGD:S000002298"
/db_xref="GeneID:851416"
/translation="MKTNKKISKRRSLKNLHGALKGLLKESGKKSESKIRKHSDCNPV
HRVYPPNIEKRKTKKDDGISRPIAERNGHVYIMSKENHIIPKLTDDEVMERHKLADEN
MRKVWSNIISKYESIEEQGDLVDLKTGEIVEDNGHIKTLTANNSTKDKRTKYTSVLRD
IIDISDEEDGDKNDEYTLWANDSEASDSEVDADNDTEEEKDEKLIDADFKKYEAKLSK
RILRD"
rep_origin 212420..212668
/note="ARS409;
Autonomously Replicating Sequence"
/db_xref="SGD:S000118430"
gene 213351..215642
/gene="RGT2"
/locus_tag="YDL138W"
/db_xref="GeneID:851417"
mRNA 213351..215642
/gene="RGT2"
/locus_tag="YDL138W"
/product="Rgt2p"
/transcript_id="NM_001180198.1"
/db_xref="GI:296143228"
/db_xref="GeneID:851417"
CDS 213351..215642
/gene="RGT2"
/locus_tag="YDL138W"
/note="Plasma membrane high glucose sensor that regulates
glucose transport; contains 12 predicted transmembrane
segments and a long C-terminal tail required for induction
of hexose transporters; highly similar to Snf3p"
/codon_start=1
/product="Rgt2p"
/protein_id="NP_010143.1"
/db_xref="GI:6320063"
/db_xref="SGD:S000002297"
/db_xref="GeneID:851417"
/translation="MNDSQNCLRQREENSHLNPGNDFGHHQGAECTINHNNMPHRNAY
TESTNDTEAKSIVMCDDPNAYQISYTNNEPAGDGAIETTSILLSQPLPLRSNVMSVLV
GIFVAVGGFLFGYDTGLINSITDMPYVKTYIAPNHSYFTTSQIAILVSFLSLGTFFGA
LIAPYISDSYGRKPTIMFSTAVIFSIGNSLQVASGGLVLLIVGRVISGIGIGIISAVV
PLYQAEAAQKNLRGAIISSYQWAITIGLLVSSAVSQGTHSKNGPSSYRIPIGLQYVWS
SILAVGMIFLPESPRYYVLKDELNKAAKSLSFLRGLPIEDPRLLEELVEIKATYDYEA
SFGPSTLLDCFKTSENRPKQILRIFTGIAIQAFQQASGINFIFYYGVNFFNNTGVDNS
YLVSFISYAVNVAFSIPGMYLVDRIGRRPVLLAGGVIMAIANLVIAIVGVSEGKTVVA
SKIMIAFICLFIAAFSATWGGVVWVVSAELYPLGVRSKCTAICAAANWLVNFTCALIT
PYIVDVGSHTSSMGPKIFFIWGGLNVVAVIVVYFAVYETRGLTLEEIDELFRKAPNSV
ISSKWNKKIRKRCLAFPISQQIEMKTNIKNAGKLDNNNSPIVQDDSHNIIDVDGFLEN
QIQSNDHMIAADKGSGSLVNIIDTAPLTSTEFKPVEHPPVNYVDLGNGLGLNTYNRGP
PSIISDSTDEFYEENDSSYYNNNTERNGANSVNTYMAQLINSSSTTSNDTSFSPSHNS
NARTSSNWTSDLASKHSQYTSPQ"
gene 216529..217074
/gene="ARF2"
/locus_tag="YDL137W"
/db_xref="GeneID:851418"
mRNA 216529..217074
/gene="ARF2"
/locus_tag="YDL137W"
/product="Arf2p"
/transcript_id="NM_001180197.1"
/db_xref="GI:296143229"
/db_xref="GeneID:851418"
CDS 216529..217074
/gene="ARF2"
/locus_tag="YDL137W"
/note="ADP-ribosylation factor; GTPase of the Ras
superfamily involved in regulation of coated formation
vesicles in intracellular trafficking within the Golgi;
ARF2 has a paralog, ARF1, that arose from the whole genome
duplication"
/codon_start=1
/product="Arf2p"
/protein_id="NP_010144.1"
/db_xref="GI:6320064"
/db_xref="SGD:S000002296"
/db_xref="GeneID:851418"
/translation="MGLYASKLFSNLFGNKEMRILMVGLDGAGKTTVLYKLKLGEVIT
TIPTIGFNVETVQYKNISFTVWDVGGQDRIRSLWRHYYRNTEGVIFVIDSNDRSRIGE
AREVMQRMLNEDELRNAVWLVFANKQDLPEAMSAAEITEKLGLHSIRNRPWFIQSTCA
TSGEGLYEGLEWLSNNLKNQS"
gene 217600..218367
/gene="RPL35B"
/locus_tag="YDL136W"
/gene_synonym="SOS2"
/db_xref="GeneID:851419"
mRNA join(217600..217602,218008..218367)
/gene="RPL35B"
/locus_tag="YDL136W"
/gene_synonym="SOS2"
/product="ribosomal 60S subunit protein L35B"
/transcript_id="NM_001180251.2"
/db_xref="GI:330443501"
/db_xref="GeneID:851419"
CDS join(217600..217602,218008..218367)
/gene="RPL35B"
/locus_tag="YDL136W"
/gene_synonym="SOS2"
/note="Ribosomal 60S subunit protein L35B; homologous to
mammalian ribosomal protein L35 and bacterial L29; RPL35B
has a paralog, RPL35A, that arose from the whole genome
duplication"
/codon_start=1
/product="ribosomal 60S subunit protein L35B"
/protein_id="NP_010090.1"
/db_xref="GI:6320010"
/db_xref="SGD:S000002295"
/db_xref="GeneID:851419"
/translation="MAGVKAYELRTKSKEQLASQLVDLKKELAELKVQKLSRPSLPKI
KTVRKSIACVLTVINEQQREAVRQLYKGKKYQPKDLRAKKTRALRRALTKFEASQVTE
KQRKKQIAFPQRKYAIKA"
gene complement(218680..219288)
/gene="RDI1"
/locus_tag="YDL135C"
/db_xref="GeneID:851420"
mRNA complement(218680..219288)
/gene="RDI1"
/locus_tag="YDL135C"
/product="Rdi1p"
/transcript_id="NM_001180195.1"
/db_xref="GI:296143231"
/db_xref="GeneID:851420"
CDS complement(218680..219288)
/gene="RDI1"
/locus_tag="YDL135C"
/note="Rho GDP dissociation inhibitor; involved in the
localization and regulation of Cdc42p and Rho1p; protein
abundance increases in response to DNA replication stress"
/codon_start=1
/product="Rdi1p"
/protein_id="NP_010146.1"
/db_xref="GI:6320066"
/db_xref="SGD:S000002294"
/db_xref="GeneID:851420"
/translation="MAEESTDFSQFEEERNNDQYKVSAKKTVDEYKNLDAEDESLAKW
KESLGLSSDVLPLEFPGDKRKVVVQKIQLLVNTEPNPITFDLTNEKTIKELASKRYKI
KENSIYKLKIVFKVQHEIITGLRYVQYIKKAGIAVDKIDDHLGSYAPNTKTKPFYEVE
LPESEAPSGFLARGNYSAVSKFIDDDKTNHLTLNWGVEIVKK"
gene complement(219662..220771)
/gene="PPH21"
/locus_tag="YDL134C"
/gene_synonym="PPH1"
/db_xref="GeneID:851421"
mRNA complement(219662..220771)
/gene="PPH21"
/locus_tag="YDL134C"
/gene_synonym="PPH1"
/product="Pph21p"
/transcript_id="NM_001180193.1"
/db_xref="GI:296143232"
/db_xref="GeneID:851421"
CDS complement(219662..220771)
/gene="PPH21"
/locus_tag="YDL134C"
/gene_synonym="PPH1"
/EC_number="3.1.3.16"
/note="Catalytic subunit of protein phosphatase 2A (PP2A);
functionally redundant with Pph22p; methylated at C
terminus; forms alternate complexes with several
regulatory subunits; involved in signal transduction and
regulation of mitosis; forms nuclear foci upon DNA
replication stress"
/codon_start=1
/product="Pph21p"
/protein_id="NP_010147.1"
/db_xref="GI:6320067"
/db_xref="SGD:S000002292"
/db_xref="GeneID:851421"
/translation="MDTDLDVPMQDAVTEQLTPTVSEDMDLNNNSSDNNAEEFSVDDL
KPGSSGIADHKSSKPLELNNTNINQLDQWIEHLSKCEPLSEDDVARLCKMAVDVLQFE
ENVKPINVPVTICGDVHGQFHDLLELFKIGGPCPDTNYLFMGDYVDRGYYSVETVSYL
VAMKVRYPHRITILRGNHESRQITQVYGFYDECLRKYGSANVWKMFTDLFDYFPITAL
VDNKIFCLHGGLSPMIETIDQVRELNRIQEVPHEGPMCDLLWSDPDDRGGWGISPRGA
GFTFGQDVSEQFNHTNDLSLIARAHQLVMEGYAWSHQQNVVTIFSAPNYCYRCGNQAA
IMEVDENHNRQFLQYDPSVRPGEPSVSRKTPDYFL"
gene complement(221724..221801)
/gene="RPL41B"
/locus_tag="YDL133C-A"
/gene_synonym="RPL47B; YDL134C-A"
/db_xref="GeneID:851422"
mRNA complement(221724..221801)
/gene="RPL41B"
/locus_tag="YDL133C-A"
/gene_synonym="RPL47B; YDL134C-A"
/product="ribosomal 60S subunit protein L41B"
/transcript_id="NM_001180194.1"
/db_xref="GI:296143233"
/db_xref="GeneID:851422"
CDS complement(221724..221801)
/gene="RPL41B"
/locus_tag="YDL133C-A"
/gene_synonym="RPL47B; YDL134C-A"
/note="Ribosomal 60S subunit protein L41B; comprises only
25 amino acids; rpl41a rpl41b double null mutant is
viable; homologous to mammalian ribosomal protein L41, no
bacterial homolog; RPL41B has a paralog, RPL41A, that
arose from the whole genome duplication"
/codon_start=1
/product="ribosomal 60S subunit protein L41B"
/protein_id="NP_010148.1"
/db_xref="GI:6320068"
/db_xref="SGD:S000002293"
/db_xref="GeneID:851422"
/translation="MRAKWRKKRTRRLKRKRRKVRARSK"
gene 222427..223740
/gene="SRF1"
/locus_tag="YDL133W"
/db_xref="GeneID:851423"
mRNA 222427..223740
/gene="SRF1"
/locus_tag="YDL133W"
/product="Srf1p"
/transcript_id="NM_001180192.1"
/db_xref="GI:296143234"
/db_xref="GeneID:851423"
CDS 222427..223740
/gene="SRF1"
/locus_tag="YDL133W"
/note="Regulator of phospholipase D (Spo14p); interacts
with Spo14p and regulates its catalytic activity; capable
of buffering the toxicity of C16:0 platelet activating
factor, a lipid that accumulates intraneuronally in
Alzheimer's patients"
/codon_start=1
/product="Srf1p"
/protein_id="NP_010149.1"
/db_xref="GI:6320069"
/db_xref="SGD:S000002291"
/db_xref="GeneID:851423"
/translation="MGDSNSSQEAYSDTTSTNASRIADQNQLNLNVDLEKNQTVRKSG
SLEALQNAKIHVPKHSDGSPLDYPKLNTYTFVPTTVPPYVLEAQFDKLRLQDKGTVDG
NVTDDKNLPKEFKWGQFASTIGCHSAYTRDQNYNPSHKSYDGYSLSSSTSSKNAALRE
ILGDMCSEWGGEERLEGVLHSEIGANLEFNTTEERKEWLQYIEKVKDFYYGDNKKNPE
SPESVHNKVYKSDWVNELNKEREKWRRLKQRKLQQWRPPLTSLLLDNQYLILGLRIFT
GILSCISLALAIKIFQNSRSNNTISESKIGQQPSTIMAICVNAVAIAYIIYIAHDEFA
GKPVGLRNPLSKLKLILLDLLFIIFSSANLALAFNTRFDKEWVCTSIRRSNGSTYGYP
KIPRICRKQEALSAFLFVALFMWVITFSISIVRVVEKVSSITNRN"
gene 224304..226751
/gene="CDC53"
/locus_tag="YDL132W"
/db_xref="GeneID:851424"
mRNA 224304..226751
/gene="CDC53"
/locus_tag="YDL132W"
/product="Cdc53p"
/transcript_id="NM_001180191.1"
/db_xref="GI:296143235"
/db_xref="GeneID:851424"
CDS 224304..226751
/gene="CDC53"
/locus_tag="YDL132W"
/note="Cullin, structural protein of SCF complexes (which
also contain Skp1p, Cdc34p, Hrt1p and an F-box protein)
involved in ubiquitination; SCF promotes the G1-S
transition by targeting G1 cyclins and the Cln-CDK
inhibitor Sic1p for degradation"
/codon_start=1
/product="cullin CDC53"
/protein_id="NP_010150.1"
/db_xref="GI:6320070"
/db_xref="SGD:S000002290"
/db_xref="GeneID:851424"
/translation="MSETLPRSDDLEATWNFIEPGINQILGNEKNQASTSKRVYKILS
PTMYMEVYTAIYNYCVNKSRSSGHFSTDSRTGQSTILVGSEIYEKLKNYLKNYILNFK
QSNSETFLQFYVKRWKRFTIGAIFLNHAFDYMNRYWVQKERSDGKRHIFDVNTLCLMT
WKEVMFDPSKDVLINELLDQVTLGREGQIIQRSNISTAIKSLVALGIDPQDLKKLNLN
VYIQVFEKPFLKKTQEYYTQYTNDYLEKHSVTEYIFEAHEIIKREEKAMTIYWDDHTK
KPLSMALNKVLITDHIEKLENEFVVLLDARDIEKITSLYALIRRDFTLIPRMASVFEN
YVKKTGENEISSLLAMHKHNIMKNENANPKKLALMTAHSLSPKDYIKKLLEVHDIFSK
IFNESFPDDIPLAKALDNACGAFININEFALPAGSPKSATSKTSEMLAKYSDILLKKA
TKPEVASDMSDEDIITIFKYLTDKDAFETHYRRLFAKRLIHGTSTSAEDEENIIQRLQ
AANSMEYTGKITKMFQDIRLSKILEDDFAVALKNEPDYSKAKYPDLQPFVLAENMWPF
SYQEVEFKLPKELVPSHEKLKESYSQKHNGRILKWLWPLCRGELKADIGKPGRMPFNF
TVTLFQMAILLLYNDADVLTLENIQEGTSLTIQHIAAAMVPFIKFKLIQQVPPGLDAL
VKPETQFKLSRPYKALKTNINFASGVKNDILQSLSGGGHDNHGNKLGNKRLTEDERIE
KELNTERQIFLEACIVRIMKAKRNLPHTTLVNECIAQSHQRFNAKVSMVKRAIDSLIQ
KGYLQRGDDGESYAYLA"
gene 227393..228715
/gene="LYS21"
/locus_tag="YDL131W"
/db_xref="GeneID:851425"
mRNA 227393..228715
/gene="LYS21"
/locus_tag="YDL131W"
/product="homocitrate synthase LYS21"
/transcript_id="NM_001180190.1"
/db_xref="GI:296143236"
/db_xref="GeneID:851425"
CDS 227393..228715
/gene="LYS21"
/locus_tag="YDL131W"
/EC_number="2.3.3.14"
/note="Homocitrate synthase isozyme; catalyzes the
condensation of acetyl-CoA and alpha-ketoglutarate to form
homocitrate, which is the first step in the lysine
biosynthesis pathway; LYS21 has a paralog, LYS20, that
arose from the whole genome duplication"
/codon_start=1
/product="homocitrate synthase LYS21"
/protein_id="NP_010151.1"
/db_xref="GI:6320071"
/db_xref="SGD:S000002289"
/db_xref="GeneID:851425"
/translation="MSENNEFQSVTESTTAPTTSNPYGPNPADYLSNVKNFQLIDSTL
REGEQFANAFFDTEKKIEIARALDDFGVDYIELTSPVASEQSRKDCEAICKLGLKAKI
LTHIRCHMDDARVAVETGVDGVDVVIGTSKFLRQYSHGKDMNYIAKSAVEVIEFVKSK
GIEIRFSSEDSFRSDLVDLLNIYKTVDKIGVNRVGIADTVGCANPRQVYELIRTLKSV
VSCDIECHFHNDTGCAIANAYTALEGGARLIDVSVLGIGERNGITPLGGLMARMIVAA
PDYVRSKYKLHKIRDIENLVADAVEVNIPFNNPITGFCAFTHKAGIHAKAILANPSTY
EILDPHDFGMKRYIHFANRLTGWNAIKSRVDQLNLNLTDDQIKEVTAKIKKLGDVRPL
NIDDVDSIIKDFHAELSTPLLKPVNKGTDDDNIDISNGHVSKKAKVTK"
gene 229171..229431
/gene="STF1"
/locus_tag="YDL130W-A"
/gene_synonym="AIS2"
/db_xref="GeneID:851426"
mRNA 229171..229431
/gene="STF1"
/locus_tag="YDL130W-A"
/gene_synonym="AIS2"
/product="Stf1p"
/transcript_id="NM_001184325.1"
/db_xref="GI:296143237"
/db_xref="GeneID:851426"
CDS 229171..229431
/gene="STF1"
/locus_tag="YDL130W-A"
/gene_synonym="AIS2"
/note="Protein involved in regulation of the mitochondrial
F1F0-ATP synthase; Stf1p and Stf2p act as stabilizing
factors that enhance inhibitory action of the Inh1p
protein; protein abundance increases in response to DNA
replication stress"
/codon_start=1
/product="Stf1p"
/protein_id="NP_010152.1"
/db_xref="GI:6320072"
/db_xref="SGD:S000007232"
/db_xref="GeneID:851426"
/translation="MLNRCISRNTRLPVNLRIASRFYSDGPLGGAGPGNPQDIFIKRE
RAKEDYYARQQEREQLAHVKEQLKEHKKKLENLENKINNLSK"
gene 229906..230527
/gene="RPP1B"
/locus_tag="YDL130W"
/gene_synonym="RPL44'; RPLA3"
/db_xref="GeneID:851427"
mRNA join(229906..230019,230321..230527)
/gene="RPP1B"
/locus_tag="YDL130W"
/gene_synonym="RPL44'; RPLA3"
/product="ribosomal protein P1B"
/transcript_id="NM_001180189.1"
/db_xref="GI:296143238"
/db_xref="GeneID:851427"
CDS join(229906..230019,230321..230527)
/gene="RPP1B"
/locus_tag="YDL130W"
/gene_synonym="RPL44'; RPLA3"
/note="Ribosomal protein P1 beta, component of the
ribosomal stalk, which is involved in interaction of
translational elongation factors with ribosome;
accumulation is regulated by phosphorylation and
interaction with the P2 stalk component"
/codon_start=1
/product="ribosomal protein P1B"
/protein_id="NP_010153.1"
/db_xref="GI:6320073"
/db_xref="SGD:S000002288"
/db_xref="GeneID:851427"
/translation="MSDSIISFAAFILADAGLEITSDNLLTITKAAGANVDNVWADVY
AKALEGKDLKEILSGFHNAGPVAGAGAASGAAAAGGDAAAEEEKEEEAAEESDDDMGF
GLFD"
gene 231024..231899
/locus_tag="YDL129W"
/db_xref="GeneID:851428"
mRNA 231024..231899
/locus_tag="YDL129W"
/product="hypothetical protein"
/transcript_id="NM_001180188.1"
/db_xref="GI:296143239"
/db_xref="GeneID:851428"
CDS 231024..231899
/locus_tag="YDL129W"
/note="hypothetical protein; green fluorescent protein
(GFP)-fusion protein localizes to the cytoplasm and the
nucleus; YDL129W is not an essential gene; relative
distribution to the nucleus increases upon DNA replication
stress"
/codon_start=1
/product="hypothetical protein"
/protein_id="NP_010154.1"
/db_xref="GI:6320074"
/db_xref="SGD:S000002287"
/db_xref="GeneID:851428"
/translation="MELRSRRSAEAYLVTPEEPAKNKSERSIESNERVGTREAKSENT
SVFSPAYSDTATTDSSKKVDDNEYYNFTSHFMPSLKNTRELENTILNLIQRIKEGDDE
TLVSEKDLILSVLNRSLASTSHWKLQAQLSELRATSEGRYAVETNLLKKEVEFLKNKT
PKTNESASSAELRPLLERPLKRKLSLPGLAQRPLSTGARLEGGYGGVSPNSWKTKVPK
LPLPASRPSLNLSPQKVPTGTDKVEEDTKIDTLELVENNKPHPRMRRRSDNPATNEYV
RVFHLEKKEPKSRKK"
gene 232652..233887
/gene="VCX1"
/locus_tag="YDL128W"
/gene_synonym="HUM1; MNR1"
/db_xref="GeneID:851429"
mRNA 232652..233887
/gene="VCX1"
/locus_tag="YDL128W"
/gene_synonym="HUM1; MNR1"
/product="Vcx1p"
/transcript_id="NM_001180187.1"
/db_xref="GI:296143240"
/db_xref="GeneID:851429"
CDS 232652..233887
/gene="VCX1"
/locus_tag="YDL128W"
/gene_synonym="HUM1; MNR1"
/note="Vacuolar membrane antiporter with Ca2+/H+ and K+/H+
exchange activity, involved in control of cytosolic Ca2+
and K+ concentrations; has similarity to sodium/calcium
exchangers, including the bovine Na+/Ca2+,K+ antiporter"
/codon_start=1
/product="Vcx1p"
/protein_id="NP_010155.1"
/db_xref="GI:6320075"
/db_xref="SGD:S000002286"
/db_xref="GeneID:851429"
/translation="MDATTPLLTVANSHPARNPKHTAWRAAVYDLQYILKASPLNFLL
VFVPLGLIWGHFQLSHTLTFLFNFLAIIPLAAILANATEELADKAGNTIGGLLNATFG
NAVELIVSIIALKKGQVRIVQASMLGSLLSNLLLVLGLCFIFGGYNRVQQTFNQTAAQ
TMSSLLAIACASLLIPAAFRATLPHGKEDHFIDGKILELSRGTSIVILIVYVLFLYFQ
LGSHHALFEQQEEETDEVMSTISRNPHHSLSVKSSLVILLGTTVIISFCADFLVGTID
NVVESTGLSKTFIGLIVIPIVGNAAEHVTSVLVAMKDKMDLALGVAIGSSLQVALFVT
PFMVLVGWMIDVPMTLNFSTFETATLFIAVFLSNYLILDGESNWLEGVMSLAMYILIA
MAFFYYPDEKTLDSIGNSL"
gene 234927..235853
/gene="PCL2"
/locus_tag="YDL127W"
/gene_synonym="CLN4"
/db_xref="GeneID:851430"
mRNA 234927..235853
/gene="PCL2"
/locus_tag="YDL127W"
/gene_synonym="CLN4"
/product="Pcl2p"
/transcript_id="NM_001180186.1"
/db_xref="GI:296143241"
/db_xref="GeneID:851430"
CDS 234927..235853
/gene="PCL2"
/locus_tag="YDL127W"
/gene_synonym="CLN4"
/note="Cyclin, interacts with cyclin-dependent kinase
Pho85p; member of the Pcl1,2-like subfamily, involved in
the regulation of polarized growth and morphogenesis and
progression through the cell cycle; localizes to sites of
polarized cell growth"
/codon_start=1
/product="Pcl2p"
/protein_id="NP_010156.2"
/db_xref="GI:42742057"
/db_xref="SGD:S000002285"
/db_xref="GeneID:851430"
/translation="MSNYEALLKFNRKAVSKEMVQYLASTTASIIKIKKTNSMIDIAL
PAPPLTKFINRLIKHSNVQTPTLMATSVYLAKLRSIIPSNVYGIETTRHRIFLGCLIL
AAKTLNDSSPLNKHWAEYTDGLLILREVNTIERELLEYFDWDVTISTDDLITCLSPFL
KPIKEEQLYKSQRDCRTLKNFSAQEKDIVNKTSISHSRSSSNMSIPSLASTSTLSTLE
SRRSNLSNYSNRIRTLPELHESNNISDKFSPRTYNIDSKHDNKENRPIPTIKPFNFSK
ARPVILKTGLNKQIIKEDTKVKKSNWSNYFKS"
gene complement(236157..238664)
/gene="CDC48"
/locus_tag="YDL126C"
/db_xref="GeneID:851431"
mRNA complement(236157..238664)
/gene="CDC48"
/locus_tag="YDL126C"
/product="Cdc48p"
/transcript_id="NM_001180185.1"
/db_xref="GI:296143242"
/db_xref="GeneID:851431"
CDS complement(236157..238664)
/gene="CDC48"
/locus_tag="YDL126C"
/note="AAA ATPase involved in multiple processes; subunit
of a polyubiquitin-selective segregase complex involved in
ERAD, cell wall integrity during heat stress and mitotic
spindle disassembly; subunit of a complex involved in
mitochondria-associated degradation; role in mobilizing
membrane bound transcription factors by regulated
ubiquitin/proteasome-dependent processing; roles in
macroautophagy, PMN, ribophagy, and homotypic ER membrane
fusion; functional ortholog of p97/VCP"
/codon_start=1
/product="AAA family ATPase CDC48"
/protein_id="NP_010157.1"
/db_xref="GI:6320077"
/db_xref="SGD:S000002284"
/db_xref="GeneID:851431"
/translation="MGEEHKPLLDASGVDPREEDKTATAILRRKKKDNMLLVDDAIND
DNSVIAINSNTMDKLELFRGDTVLVKGKKRKDTVLIVLIDDELEDGACRINRVVRNNL
RIRLGDLVTIHPCPDIKYATRISVLPIADTIEGITGNLFDVFLKPYFVEAYRPVRKGD
HFVVRGGMRQVEFKVVDVEPEEYAVVAQDTIIHWEGEPINREDEENNMNEVGYDDIGG
CRKQMAQIREMVELPLRHPQLFKAIGIKPPRGVLMYGPPGTGKTLMARAVANETGAFF
FLINGPEVMSKMAGESESNLRKAFEEAEKNAPAIIFIDEIDSIAPKRDKTNGEVERRV
VSQLLTLMDGMKARSNVVVIAATNRPNSIDPALRRFGRFDREVDIGIPDATGRLEVLR
IHTKNMKLADDVDLEALAAETHGYVGADIASLCSEAAMQQIREKMDLIDLDEDEIDAE
VLDSLGVTMDNFRFALGNSNPSALRETVVESVNVTWDDVGGLDEIKEELKETVEYPVL
HPDQYTKFGLSPSKGVLFYGPPGTGKTLLAKAVATEVSANFISVKGPELLSMWYGESE
SNIRDIFDKARAAAPTVVFLDELDSIAKARGGSLGDAGGASDRVVNQLLTEMDGMNAK
KNVFVIGATNRPDQIDPAILRPGRLDQLIYVPLPDENARLSILNAQLRKTPLEPGLEL
TAIAKATQGFSGADLLYIVQRAAKYAIKDSIEAHRQHEAEKEVKVEGEDVEMTDEGAK
AEQEPEVDPVPYITKEHFAEAMKTAKRSVSDAELRRYEAYSQQMKASRGQFSNFNFND
APLGTTATDNANSNNSAPSGAGAAFGSNAEEDDDLYS"
gene complement(239019..239606)
/gene="HNT1"
/locus_tag="YDL125C"
/db_xref="GeneID:851432"
mRNA complement(join(239019..239398,239510..239606))
/gene="HNT1"
/locus_tag="YDL125C"
/product="Hnt1p"
/transcript_id="NM_001180184.1"
/db_xref="GI:296143243"
/db_xref="GeneID:851432"
CDS complement(join(239019..239398,239510..239606))
/gene="HNT1"
/locus_tag="YDL125C"
/EC_number="3.-.-.-"
/note="Adenosine 5'-monophosphoramidase; interacts
physically and genetically with Kin28p, a CDK and TFIIK
subunit, and genetically with CAK1; member of the
histidine triad (HIT) superfamily of nucleotide-binding
proteins and similar to Hint; protein abundance increases
in response to DNA replication stress"
/codon_start=1
/product="Hnt1p"
/protein_id="NP_010158.1"
/db_xref="GI:6320078"
/db_xref="SGD:S000002283"
/db_xref="GeneID:851432"
/translation="MEPLISAPYLTTTKMSAPATLDAACIFCKIIKSEIPSFKLIETK
YSYAFLDIQPTAEGHALIIPKYHGAKLHDIPDEFLTDAMPIAKRLAKAMKLDTYNVLQ
NNGKIAHQEVDHVHFHLIPKRDEKSGLIVGWPAQETDFDKLGKLHKELLAKLEGSD"
gene 240259..241197
/locus_tag="YDL124W"
/db_xref="GeneID:851433"
mRNA 240259..241197
/locus_tag="YDL124W"
/product="aldo-keto reductase superfamily protein"
/transcript_id="NM_001180183.1"
/db_xref="GI:296143244"
/db_xref="GeneID:851433"
CDS 240259..241197
/locus_tag="YDL124W"
/EC_number="1.2.1.-"
/note="NADPH-dependent alpha-keto amide reductase; reduces
aromatic alpha-keto amides, aliphatic alpha-keto esters,
and aromatic alpha-keto esters; member of the aldo-keto
reductase (AKR) family; protein abundance increases in
response to DNA replication stress"
/codon_start=1
/product="aldo-keto reductase superfamily protein"
/protein_id="NP_010159.1"
/db_xref="GI:6320079"
/db_xref="SGD:S000002282"
/db_xref="GeneID:851433"
/translation="MSFHQQFFTLNNGNKIPAIAIIGTGTRWYKNEETDATFSNSLVE
QIVYALKLPGIIHIDAAEIYRTYPEVGKALSLTEKPRNAIFLTDKYSPQIKMSDSPAD
GLDLALKKMGTDYVDLYLLHSPFVSKEVNGLSLEEAWKDMEQLYKSGKAKNIGVSNFA
VEDLQRILKVAEVKPQVNQIEFSPFLQNQTPGIYKFCQEHDILVEAYSPLGPLQKKTA
QDDSQPFFEYVKELSEKYIKSEAQIILRWVTKRGVLPVTTSSKPQRISDAQNLFSFDL
TAEEVDKITELGLEHEPLRLYWNKLYGKYNYAAQKV"
gene 241418..241840
/gene="SNA4"
/locus_tag="YDL123W"
/db_xref="GeneID:851434"
mRNA 241418..241840
/gene="SNA4"
/locus_tag="YDL123W"
/product="Sna4p"
/transcript_id="NM_001180182.1"
/db_xref="GI:296143245"
/db_xref="GeneID:851434"
CDS 241418..241840
/gene="SNA4"
/locus_tag="YDL123W"
/note="hypothetical protein, localized to the vacuolar
outer membrane; predicted to be palmitoylated"
/codon_start=1
/product="Sna4p"
/protein_id="NP_010160.1"
/db_xref="GI:6320080"
/db_xref="SGD:S000002281"
/db_xref="GeneID:851434"
/translation="MCCYCVCCTVSDFILYIVAFFFPPAAVLLRSGPCSSDFLLNVLL
TLLGFLPGMLHAFYYITITSPLRNAEYVYYYQQGWVDSERNVPSNRPQNSQTPQNRPQ
QGSSARNVYPSVETPLLQGAAPHDNKQSLVESPPPYVP"
gene 242552..244981
/gene="UBP1"
/locus_tag="YDL122W"
/db_xref="GeneID:851435"
mRNA 242552..244981
/gene="UBP1"
/locus_tag="YDL122W"
/product="Ubp1p"
/transcript_id="NM_001180181.1"
/db_xref="GI:296143246"
/db_xref="GeneID:851435"
CDS 242552..244981
/gene="UBP1"
/locus_tag="YDL122W"
/EC_number="3.1.2.15"
/note="Ubiquitin-specific protease that removes ubiquitin
from ubiquitinated proteins; cleaves at the C terminus of
ubiquitin fusions irrespective of their size; capable of
cleaving polyubiquitin chains"
/codon_start=1
/product="Ubp1p"
/protein_id="NP_010161.1"
/db_xref="GI:6320081"
/db_xref="SGD:S000002280"
/db_xref="GeneID:851435"
/translation="MDLFIESKINSLLQFLFGSRQDFLRNFKTWSNNNNNLSIYLLIF
GIVVFFYKKPDHLNYIVESVSEMTTNFRNNNSLSRWLPRSKFTHLDEEILKRGGFIAG
LVNDGNTCFMNSVLQSLASSRELMEFLDNNVIRTYEEIEQNEHNEEGNGQESAQDEAT
HKKNTRKGGKVYGKHKKKLNRKSSSKEDEEKSQEPDITFSVALRDLLSALNAKYYRDK
PYFKTNSLLKAMSKSPRKNILLGYDQEDAQEFFQNILAELESNVKSLNTEKLDTTPVA
KSELPDDALVGQLNLGEVGTVYIPTEQIDPNSILHDKSIQNFTPFKLMTPLDGITAER
IGCLQCGENGGIRYSVFSGLSLNLPNENIGSTLKLSQLLSDWSKPEIIEGVECNRCAL
TAAHSHLFGQLKEFEKKPEGSIPEKLINAVKDRVHQIEEVLAKPVIDDEDYKKLHTAN
MVRKCSKSKQILISRPPPLLSIHINRSVFDPRTYMIRKNNSKVLFKSRLNLAPWCCDI
NEINLDARLPMSKKEKAAQQDSSEDENIGGEYYTKLHERFEQEFEDSEEEKEYDDAEG
NYASHYNHTKDISNYDPLNGEVDGVTSDDEDEYIEETDALGNTIKKRIIEHSDVENEN
VKDNEELQEIDNVSLDEPKINVEDQLETSSDEEDVIPAPPINYARSFSTVPATPLTYS
LRSVIVHYGTHNYGHYIAFRKYRGCWWRISDETVYVVDEAEVLSTPGVFMLFYEYDFD
EETGKMKDDLEAIQSNNEEDDEKEQEQKGVQEPKESQEQGEGEEQEEGQEQMKFERTE
DHRDISGKDVN"
gene complement(245133..245582)
/locus_tag="YDL121C"
/db_xref="GeneID:851436"
mRNA complement(245133..245582)
/locus_tag="YDL121C"
/product="hypothetical protein"
/transcript_id="NM_001180180.1"
/db_xref="GI:296143247"
/db_xref="GeneID:851436"
CDS complement(245133..245582)
/locus_tag="YDL121C"
/note="hypothetical protein; green fluorescent protein
(GFP)-fusion protein localizes to the endoplasmic
reticulum; YDL121C is not an essential protein"
/codon_start=1
/product="hypothetical protein"
/protein_id="NP_010162.1"
/db_xref="GI:6320082"
/db_xref="SGD:S000002279"
/db_xref="GeneID:851436"
/translation="MNLYGYFLLLIIVIAFIALLPLFSGIGTFKLTKPKSSATAQSAT
GKLGKREYLKKKLDHTNVLKFDLKDTEESLGHDSASASSASRKFEIDSKTGLKRRVIG
QYNKDPNDFDFDIDDLINEDELDERREEEKKLKKYNGKKNEAYEGFV"
gene 245923..246447
/gene="YFH1"
/locus_tag="YDL120W"
/db_xref="GeneID:851437"
mRNA 245923..246447
/gene="YFH1"
/locus_tag="YDL120W"
/product="Yfh1p"
/transcript_id="NM_001180179.1"
/db_xref="GI:296143248"
/db_xref="GeneID:851437"
CDS 245923..246447
/gene="YFH1"
/locus_tag="YDL120W"
/note="Mitochondrial matrix iron chaperone; oxidizes and
stores iron; interacts with Isu1p to promote Fe-S cluster
assembly; mutation results in multiple Fe/S-dependent
enzyme deficiencies; human frataxin homolog is mutated in
Friedrich's ataxia"
/codon_start=1
/product="Yfh1p"
/protein_id="NP_010163.1"
/db_xref="GI:6320083"
/db_xref="SGD:S000002278"
/db_xref="GeneID:851437"
/translation="MIKRSLASLVRVSSVMGRRYMIAAAGGERARFCPAVTNKKNHTV
NTFQKRFVESSTDGQVVPQEVLNLPLEKYHEEADDYLDHLLDSLEELSEAHPDCIPDV
ELSHGVMTLEIPAFGTYVINKQPPNKQIWLASPLSGPNRFDLLNGEWVSLRNGTKLTD
ILTEEVEKAISKSQ"
gene complement(246689..247612)
/locus_tag="YDL119C"
/db_xref="GeneID:851439"
mRNA complement(246689..247612)
/locus_tag="YDL119C"
/product="hypothetical protein"
/transcript_id="NM_001180178.1"
/db_xref="GI:296143249"
/db_xref="GeneID:851439"
CDS complement(246689..247612)
/locus_tag="YDL119C"
/note="Putative mitochondrial transport protein;
GFP-fusion protein is induced in response to the
DNA-damaging agent MMS; the authentic, non-tagged protein
is detected in purified mitochondria"
/codon_start=1
/product="hypothetical protein"
/protein_id="NP_010164.1"
/db_xref="GI:6320085"
/db_xref="SGD:S000002277"
/db_xref="GeneID:851439"
/translation="MTEQATKPRNSSHLIGGFFGGLTSAVALQPLDLLKTRIQQDKKA
TLWKNLKEIDSPLQLWRGTLPSALRTSIGSALYLSCLNLMRSSLAKRRNAVPSLTNDS
NIVYNKSSSLPRLTMYENLLTGAFARGLVGYITMPITVIKVRYESTLYNYSSLKEAIT
HIYTKEGLFGFFRGFGATCLRDAPYAGLYVLLYEKSKQLLPMVLPSRFIHYNPEGGFT
TYTSTTVNTTSAVLSASLATTVTAPFDTIKTRMQLEPSKFTNSFNTFTSIVKNENVLK
LFSGLSMRLARKAFSAGIAWGIYEELVKRFM"
gene 248581..251238
/gene="CYK3"
/locus_tag="YDL117W"
/db_xref="GeneID:851440"
mRNA 248581..251238
/gene="CYK3"
/locus_tag="YDL117W"
/product="Cyk3p"
/transcript_id="NM_001180176.1"
/db_xref="GI:296143251"
/db_xref="GeneID:851440"
CDS 248581..251238
/gene="CYK3"
/locus_tag="YDL117W"
/note="SH3-domain protein located in the bud neck and
cytokinetic actin ring; mutant phenotype and genetic
interactions suggest a role in cytokinesis; relocalizes
from bud neck to nucleus upon DNA replication stress"
/codon_start=1
/product="Cyk3p"
/protein_id="NP_010166.1"
/db_xref="GI:6320086"
/db_xref="SGD:S000002275"
/db_xref="GeneID:851440"
/translation="MATNLTSLKPPFKVKARYGWSGQTKGDLGFLEGDIMEVTRIAGS
WFYGKLLRNKKCSGYFPHNFVILLEERLNSSTENGRQPSKIVESFEKSNKVVIPPVPS
RYSDERPRPKKKLSSSMPNSPKKPVDSLTKARKAKSKEMVNEKNIYNTQSSRHHNNSA
PNLPLASHSKPQVRNFEESMNNPLPPLPPLPDLDNMRKTDKRAPKKSYSANDLHMARS
SREYNYYKDNQKFYDGFIPEKRYSLEEDSISSGLFSNSQYLNDSACSSENSFALMSDF
SATSAGSFARHKYAQSFSDSLQRSQNANGCSTKINDSQEFGDSNASSRNGKMGDILRK
IIIPKRNTNIYSSSVSSPKSPKAYPKLPDIQNLNLSATPDEARDWIAVKCHLNRARTL
TKYDKHPRYMRALEENRDLILHPQDSIYNGLNTNEVKGNTKPGLVDVELAELNIEYID
KMTWKRCIRDGTMTLDSWAQTTFSARYSTVLEKLRGIYIFCTEMFALTDDNGTSDFSA
EPQNLEKILYRKHCTPYELTWLFKKLANSLGITCEIVIGFLKTPSAINWEFKYNHCWL
RILVNKEWRFIDVILGNVTNPIHEFVNNRKIKKAENSYFLMAPLEMIYTHIPPREFEQ
HIVPSIDQLSALYLPLVFPSFFKNELKLYKFSTALSFLEDSEIYECSLEIPNDVEVFA
SVVIPTDNEEASSAYRNMELALTQIKKQKAESGRRIALIKAVLPPNVNKGSLYIHSGV
RGTQTSIANIHPLSMMVPLTHKGSNMKYEFVIKIPSESIQKIELYIVEPQSRYLFVGN
EYSFEVIQSPSDGIVYSSDEGPNQNRKQPMAIKSPSGRVHELVKSDPHFPYGTWKGSI
KIKEPGVWSALVIADSGIGWSVFAEWLCV"
gene 251566..253746
/gene="NUP84"
/locus_tag="YDL116W"
/db_xref="GeneID:851441"
mRNA 251566..253746
/gene="NUP84"
/locus_tag="YDL116W"
/product="Nup84p"
/transcript_id="NM_001180175.1"
/db_xref="GI:296143252"
/db_xref="GeneID:851441"
CDS 251566..253746
/gene="NUP84"
/locus_tag="YDL116W"
/note="Subunit of the Nup84p subcomplex of the nuclear
pore complex (NPC); contributes to nucleocytoplasmic
transport and NPC biogenesis; also plays roles in several
processes that may require localization of genes or
chromosomes at the nuclear periphery, including
double-strand break repair, transcription and chromatin
silencing; homologous to human NUP107"
/codon_start=1
/product="Nup84p"
/protein_id="NP_010167.1"
/db_xref="GI:6320087"
/db_xref="SGD:S000002274"
/db_xref="GeneID:851441"
/translation="MELSPTYQTERFTKFSDTLKEFKIEQNNEQNPIDPFNIIREFRS
AAGQLALDLANSGDESNVISSKDWELEARFWHLVELLLVFRNADLDLDEMELHPYNSR
GLFEKKLMQDNKQLYQIWIVMVWLKENTYVMERPKNVPTSKWLNSITSGGLKSCDLDF
PLRENTNVLDVKDKEEDHIFFKYIYELILAGAIDEALEEAKLSDNISICMILCGIQEY
LNPVIDTQIANEFNTQQGIKKHSLWRRTVYSLSQQAGLDPYERAIYSYLSGAIPNQEV
LQYSDWESDLHIHLNQILQTEIENYLLENNQVGTDELILPLPSHALTVQEVLNRVASR
HPSESEHPIRVLMASVILDSLPSVIHSSVEMLLDVVKGTEASNDIIDKPYLLRIVTHL
AICLDIINPGSVEEVDKSKLITTYISLLKLQGLYENIPIYATFLNESDCLEACSFILS
SLEDPQVRKKQIETINFLRLPASNILRRTTQRVFDETEQEYSPSNEISISFDVNNIDM
HLIYGVEWLIEGKLYVDAVHSIIALSRRFLLNGRVKALEQFMERNNIGEICKNYELEK
IADNISKDENEDQFLEEITQYEHLIKGIREYEEWQKSVSLLSSESNIPTLIEKLQGFS
KDTFELIKTFLVDLTSSNFADSADYEILYEIRALYTPFLLMELHKKLVEAAKLLKIPK
FISEALAFTSLVANENDKIYLLFQSSGKLKEYLDLVARTATLSN"
rep_origin 253791..254039
/note="ARS410;
Autonomously Replicating Sequence"
/db_xref="SGD:S000118431"
gene complement(253995..255126)
/gene="IWR1"
/locus_tag="YDL115C"
/db_xref="GeneID:851442"
mRNA complement(join(253995..254974,255045..255126))
/gene="IWR1"
/locus_tag="YDL115C"
/product="Iwr1p"
/transcript_id="NM_001180174.1"
/db_xref="GI:296143253"
/db_xref="GeneID:851442"
CDS complement(join(253995..254974,255045..255126))
/gene="IWR1"
/locus_tag="YDL115C"
/note="RNA polymerase II transport factor, conserved from
yeast to humans; also has a role in transporting RNA
polymerase III into the nucleus; interacts with most of
the RNAP II subunits; nucleo-cytoplasmic shuttling
protein; deletion causes hypersensitivity to K1 killer
toxin; protein increases in abundance and relocalizes from
nucleus to cytoplasm upon DNA replication stress"
/codon_start=1
/product="Iwr1p"
/protein_id="NP_010168.4"
/db_xref="GI:154199603"
/db_xref="SGD:S000002273"
/db_xref="GeneID:851442"
/translation="MSTISTTTAPEFIRVKRRRDEDSVQALLIDEGKRVKKQKFIFKL
SKTVSSESYQSEQESSTPLLKLAHEDHRHFVLEQRKKSRRDSDDEKSQQRLAAEGSTV
DDDGLPPEINQMVNDYLKLNKGVEKTERKKPSRKYFTGDSAKIASLPSLDYVFDIYHL
EKIHDDEVARYNNEKNIGFVKIIEHIDLALDEESDPNEARSDDEDSNDENYYQNDYPE
DEDDDRSILFGSEGEDIAALGEEIVIGVNKSRFSSWNDDKIQGSNGYHDVEEEYGDLF
NRLGGKSDVLKSINSSNFIDLDGQEGEIEISDNEDDSDEGDDIEYPRNEFFPTDVDDP
LAHHRDRIFHQLQKKINRS"
gene 255604..256530
/locus_tag="YDL114W"
/db_xref="GeneID:851444"
mRNA 255604..256530
/locus_tag="YDL114W"
/product="short-chain dehydrogenase/reductase"
/transcript_id="NM_001180173.1"
/db_xref="GI:296143254"
/db_xref="GeneID:851444"
CDS 255604..256530
/locus_tag="YDL114W"
/EC_number="1.-.-.-"
/note="Putative short-chain dehydrogenase/reductase;
YDL114W is not an essential gene"
/codon_start=1
/product="short-chain dehydrogenase/reductase"
/protein_id="NP_010169.1"
/db_xref="GI:6320089"
/db_xref="SGD:S000002272"
/db_xref="GeneID:851444"
/translation="MVRKNKINRASGTTKHLKDFPSVILSLPSYNPSILSKNATALIT
GGSSGLGFELAKELSRRINKVIVADIQSFPTFAQVEYNNIFYYQCDITSLDEIKNLKK
AIERDHGNINIIINNAGVAHIKKLEHMTNKEVEQLIDINLIGAYRIISTFAEDMIDNR
EGFIINIASVLGELTPARLTSYGASKGAMIGFHKCMSRHFRSLSTECNKTGIKTLLVC
PGKIKTNMFIDVPTPSKLLAPDIIPSQLALAIISAMEHNHLQTLNAPYYVNLVPFFKT
LSWPYRHLLKHFSGMDHVTSTSPRAINPKRSA"
rep_origin 256530..256633
/note="ARS411;
Putative replication origin, identified in multiple array
studies, not yet confirmed by plasmid-based assay"
/db_xref="SGD:S000130171"
gene complement(256633..258555)
/gene="ATG20"
/locus_tag="YDL113C"
/gene_synonym="CVT20; SNX42"
/db_xref="GeneID:851445"
mRNA complement(256633..258555)
/gene="ATG20"
/locus_tag="YDL113C"
/gene_synonym="CVT20; SNX42"
/product="Atg20p"
/transcript_id="NM_001180172.1"
/db_xref="GI:296143255"
/db_xref="GeneID:851445"
CDS complement(256633..258555)
/gene="ATG20"
/locus_tag="YDL113C"
/gene_synonym="CVT20; SNX42"
/note="Sorting nexin family member required for the
cytoplasm-to-vacuole targeting (Cvt) pathway and for
endosomal sorting; has a Phox homology domain that binds
phosphatidylinositol-3-phosphate; interacts with Snx4p;
potential Cdc28p substrate"
/codon_start=1
/product="Atg20p"
/protein_id="NP_010170.1"
/db_xref="GI:6320090"
/db_xref="SGD:S000002271"
/db_xref="GeneID:851445"
/translation="MSDLNDVQENAKLNSETRNTGKAEPPHGTTEYVAEAEISKNGVG
SPKKSPKKGKVGKGDNNKVETELVHTALLEKDNPFMEEGPTGFTKSALLEIPGMRSHN
LKNPNEDYEDDSEGLLPLNQESNAETCRTSLSGSINSMNGETSASEEPSVSNRKKSAR
IHILEAKRVSEGQGRAYIAYVIQFENSTVQRRYSDFESLRSILIRLFPMTLIPPIPEK
QSIKNYGKSITGSSSKYLLPSEGSGSVDLSLSVIHASVNNSDEKLIRHRIRMLTEFLN
KLLTNEEITKTSIITDFLDPNNHNWHEFVNSSSTFSSLPKSILQCNPLDPTNTTRIHA
MLPIPGSSSQLLLNKESNDKKMDKERSKSFTNIEQDYKQYENLLDNGIYKYNRRTTKT
YHDLKSDYNEIGEVFAQFAHEQAQVGELAEQLSYLSNAFSGSSISLEKLVGRLYYNIN
EPLNESVHMATSARELIKYRKLKYLQNEMIKKSLNSKRAQLEKLEAQNNEYKDVDKII
DNEMSKSHTINLERPNNNTGSGGKSYGGKLFNGFNKLASMVKDSVKYQETDPHTASIN
LKKEIEQLSESLEVTENDLEVISKVIKNDQLPKFSKEREVDLSEILKHYSRYMRNYAR
QNLEIWKEVKRHQDFA"
gene 258915..263225
/gene="TRM3"
/locus_tag="YDL112W"
/db_xref="GeneID:851446"
mRNA 258915..263225
/gene="TRM3"
/locus_tag="YDL112W"
/product="Trm3p"
/transcript_id="NM_001180171.1"
/db_xref="GI:296143256"
/db_xref="GeneID:851446"
CDS 258915..263225
/gene="TRM3"
/locus_tag="YDL112W"
/EC_number="2.1.1.34"
/note="2'-O-ribose methyltransferase, catalyzes the ribose
methylation of the guanosine nucleotide at position 18 of
tRNAs"
/codon_start=1
/product="Trm3p"
/protein_id="NP_010171.1"
/db_xref="GI:6320091"
/db_xref="SGD:S000002270"
/db_xref="GeneID:851446"
/translation="MVGGALICKYLPREEQLKLISDLIQNDSLEEVLELIETSPLDIT
TDSNIETPIFEKITEQVIAYASIDGEAREMFRSSRAEMNKALRTSAQLLCCLPSVWHK
FQVWMSYRLNDIISENYKHLFNDNFGKKIVQPFFDSFAEEQNANIKHENLHLDILSLL
HYLEVVYLFDECKNGISSKCLDFIIVPLLGCNSEEIADSCSKLMRWHIKYLSKCCNTD
SNFDKLIWTFIKQLYAEGSQQAWKQKNSLSFLLRFLLAAELSPELITYIKTDAYWRHI
QTELDNDVHEHRKLALSILKLTIQKLSSHGITLQTTFYKCNDLANIEMLGSWKKFTTL
YEMIALDTSLNQIQAAKQDIIKIFDNEHLHHSWGLILLSTGLKSSMESVRKYMMTLMF
SITNMSAFSSNLPLLTKTLLPAAMSAHYFDVKGVSCPHGEKLSLFVNNLLSQTTEGIS
DILFEILKLLVEKGTSFDPSRIYLSYGILVFFQNNKQKTINSDHLSLIRKLYDFAAEE
EVLETTIQTIYLKFLLYIDPSVSASELLFTLVSHIKLKGGTYKYVEPLFEDYRDLAVS
HFDDLQAKENLTTNIGKDTIFDLLASIIFDFKDIDITPDFLIEVAKSKQDIPVYTSKA
VTFLTQLLSGEPSNGYTYENATALLSYPNFTISTWKSINVNNLFKSVMEKFSLDKFKF
FAEIYQKTYECRFDTIELNFNDLLSLYEMVKKSANQCSRESFKVKDSAYSSYFELLNT
FLKTYALNRDSSEGNDDELHILLRLVDENINKDNGNYLGNLAVCKLLYFIIDSYIHCS
TSVSDDDIFIVKFIFEKFSFIWECINSERLVLKERDLHLMLIKGLFHPVILYFGSNQY
IDTLTSKLEEHAQTIISLSYSRRSLLPLLGSQLRVFMKFYGKLLREDVNYWWLINIIV
GVFKQPQMDVNLYKLKPVISSLFDHKLNNYYIKGDELYEKVYGPDEILARVSIIDSIL
YANDQLKIRLIEKVTEKTNALYAIKRTDGAEALQRLLQWQLLLLSLLTTNEKKLSETS
MIRILKSIEDESSPLVRVYKEWFISSKVVDYYKTGNPKFAEDYLFSLLEDHSKPVFVV
SAEKICFMVLKDLRNDEKKYGFTQLLDRFICTLVPNAASNKPLVRHFSNSLIISLWPT
FKAYLSDHTLRNIIENLYSNAKKTQIFGQYRAGDANIWDLKGDRKLTNMFGGVLKKVT
DHDCPYISESVFEKYLQEKDIVPIGTDERSLWLDKRDTNTESVNNANISCDTSPLQTK
SGAWETVLDLDNKKSNDVVTRSELIVVSSLVDKPPNLGGICRLCDVLGVGLLTVQDIK
VKNHPQFKNVAVTADRWMPMEEVALDEIASFMKEKKKEGYTLIGLEQTDKSVKLDNNF
QFPKKSLILLGTEAFGIPGTLLSELDLCLEIQQFGVIRSMNIQTATAVIVHSYTVQHM
"
gene complement(263313..264110)
/gene="RRP42"
/locus_tag="YDL111C"
/db_xref="GeneID:851447"
mRNA complement(263313..264110)
/gene="RRP42"
/locus_tag="YDL111C"
/product="Rrp42p"
/transcript_id="NM_001180170.1"
/db_xref="GI:296143257"
/db_xref="GeneID:851447"
CDS complement(263313..264110)
/gene="RRP42"
/locus_tag="YDL111C"
/EC_number="3.1.13.-"
/note="Exosome non-catalytic core component; involved in
3'-5' RNA processing and degradation in both the nucleus
and the cytoplasm; has similarity to E. coli RNase PH and
to human hRrp42p (EXOSC7)"
/codon_start=1
/product="Rrp42p"
/protein_id="NP_010172.1"
/db_xref="GI:6320092"
/db_xref="SGD:S000002269"
/db_xref="GeneID:851447"
/translation="MSLSVAEKSYLYDSLASTPSIRPDGRLPHQFRPIEIFTDFLPSS
NGSSRIIASDGSECIVSIKSKVVDHHVENELLQVDVDIAGQRDDALVVETITSLLNKV
LKSGSGVDSSKLQLTKKYSFKIFVDVLVISSHSHPVSLISFAIYSALNSTYLPKLISA
FDDLEVEELPTFHDYDMVKLDINPPLVFILAVVGNNMLLDPAANESEVANNGLIISWS
NGKITSPIRSVALNDSNVKSFKPHLLKQGLAMVEKYAPDVVRSLENL"
gene complement(264512..264964)
/gene="TMA17"
/locus_tag="YDL110C"
/db_xref="GeneID:851448"
mRNA complement(264512..264964)
/gene="TMA17"
/locus_tag="YDL110C"
/product="Tma17p"
/transcript_id="NM_001180169.1"
/db_xref="GI:296143258"
/db_xref="GeneID:851448"
CDS complement(264512..264964)
/gene="TMA17"
/locus_tag="YDL110C"
/note="hypothetical protein that associates with
ribosomes; heterozygous deletion demonstrated increases in
chromosome instability in a rad9 deletion background;
protein abundance is decreased upon intracellular iron
depletion"
/codon_start=1
/product="Tma17p"
/protein_id="NP_010173.1"
/db_xref="GI:6320093"
/db_xref="SGD:S000002268"
/db_xref="GeneID:851448"
/translation="MCSAGGIRRPIQIEEFKTAISGMSDMELAQIKTEIENSINHLQR
SNARLGKYIAKLEGADDRLEADDSDDLENIDSGDLALYKDSVRENEIVLNNYNERVDA
LEQETVYRKTGHGKSKHEVEAKDNTNKGPDVDMDNSNVDVVTPNSIFI"
gene complement(265258..267201)
/locus_tag="YDL109C"
/db_xref="GeneID:851449"
mRNA complement(265258..267201)
/locus_tag="YDL109C"
/product="putative lipase"
/transcript_id="NM_001180168.1"
/db_xref="GI:296143259"
/db_xref="GeneID:851449"
CDS complement(265258..267201)
/locus_tag="YDL109C"
/EC_number="3.1.-.-"
/note="Putative lipase; involved in lipid metabolism; not
an essential gene; YDL109C has a paralog, ROG1, that arose
from the whole genome duplication"
/codon_start=1
/product="putative lipase"
/protein_id="NP_010174.1"
/db_xref="GI:6320094"
/db_xref="SGD:S000002267"
/db_xref="GeneID:851449"
/translation="MEAGRSADEVLYHNQSSVKLGELERYVITYELYQGDSIPADITL
DSLWVKIKNTTKLSYKPAYLLGPFILYCDVRAKDYESSYKIICSADKPVFQSNLQAQQ
KFIAELSLHHIKPRYVWIVDIVSQILFNKETKVTFEIVVGNSKASLKRKIRCNDSLPD
KACNILHTGLSVHRLTTADIWKVPRPIDMSQKSHLVILTHGFQSNVSADMEYLMEEIY
KAQMNNPNERLVIKGYMKNACETEKGIKFLGVGLANYIIDELYDDSVGKISFIGHSLG
GLTQTFAICYIKTKYPYFFKKVEPINFISLASPLLGIATSTPNYVKMSLSMGIIGTTG
QELGLKDGNYGDKPLLYLLSEESLISVLARFKRRTLYANAVNDGIVPLYSSSLLFLDY
SQLLQKLGGQTTAPCDPLFQPEVSPIGELPNHSDVANDDDGINASSWNTFWKSKENNC
DKKSKRLMNASVIKSMKSVLLSPCPDAKFFSDPDARVATIIHDKIYTEKNLPPPSPTL
YEGTAAKEGETRKTRKEMEEIIARRWHKGMHWRKVVVLLKPDAHNNIIVRRRFSNAYG
WPVVDHLVTAHFQRDDPIASPMQDKQFAEEDINMATGGVEPNKFYSWLTKIEDPSVYH
GGIVSTASQLASSWISKHSSVTD"
gene 267698..268699
/gene="KIN28"
/locus_tag="YDL108W"
/db_xref="GeneID:851450"
mRNA join(267698..267725,267807..268699)
/gene="KIN28"
/locus_tag="YDL108W"
/product="Kin28p"
/transcript_id="NM_001180167.1"
/db_xref="GI:296143260"
/db_xref="GeneID:851450"
CDS join(267698..267725,267807..268699)
/gene="KIN28"
/locus_tag="YDL108W"
/EC_number="2.7.11.23"
/EC_number="2.7.11.1"
/note="Serine/threonine protein kinase, subunit of the
transcription factor TFIIH; involved in transcription
initiation at RNA polymerase II promoters"
/codon_start=1
/product="Kin28p"
/protein_id="NP_010175.1"
/db_xref="GI:6320095"
/db_xref="SGD:S000002266"
/db_xref="GeneID:851450"
/translation="MKVNMEYTKEKKVGEGTYAVVYLGCQHSTGRKIAIKEIKTSEFK
DGLDMSAIREVKYLQEMQHPNVIELIDIFMAYDNLNLVLEFLPTDLEVVIKDKSILFT
PADIKAWMLMTLRGVYHCHRNFILHRDLKPNNLLFSPDGQIKVADFGLARAIPAPHEI
LTSNVVTRWYRAPELLFGAKHYTSAIDIWSVGVIFAELMLRIPYLPGQNDVDQMEVTF
RALGTPTDRDWPEVSSFMTYNKLQIYPPPSRDELRKRFIAASEYALDFMCGMLTMNPQ
KRWTAVQCLESDYFKELPPPSDPSSIKIRN"
gene 268921..269976
/gene="MSS2"
/locus_tag="YDL107W"
/db_xref="GeneID:851451"
mRNA 268921..269976
/gene="MSS2"
/locus_tag="YDL107W"
/product="Mss2p"
/transcript_id="NM_001180166.1"
/db_xref="GI:296143261"
/db_xref="GeneID:851451"
CDS 268921..269976
/gene="MSS2"
/locus_tag="YDL107W"
/note="Peripherally bound inner membrane protein of the
mitochondrial matrix involved in membrane insertion of
C-terminus of Cox2p, interacts genetically and physically
with Cox18p"
/codon_start=1
/product="Mss2p"
/protein_id="NP_010176.1"
/db_xref="GI:6320096"
/db_xref="SGD:S000002265"
/db_xref="GeneID:851451"
/translation="MQRFVSKFVSTPPVPKKFQEIFPKKRTVNKILFQLDTRLTYHEM
YPIFLQVSQNTNEENIPWRKKYPYIRSSDIMQMRNVLITLRTQNKFVHKDLLAMEDKL
LNIAAELGNNDAISILSFNVIHEYKKENVKSSYEKDIETANEFIKKLYARNHHLTVKL
IGDLFFENKTYDKAEKYYQEFLKLENSTKLAGEVHGKLGEIQIKQVNGFLKAEKSWLS
CIELLEIERSSRWYFLLARLYMSSEPMKAKALLENCASIGFKECFKTLGFLELNYFNN
YERAKEWFKTGMEIMDLECFFGFFDCCVKEENFKGARDCLESVKKLGNDKDKKTMINV
FLESRKDSIKLLDKARL"
gene complement(270222..271901)
/gene="PHO2"
/locus_tag="YDL106C"
/gene_synonym="BAS2; GRF10"
/db_xref="GeneID:851452"
mRNA complement(270222..271901)
/gene="PHO2"
/locus_tag="YDL106C"
/gene_synonym="BAS2; GRF10"
/product="Pho2p"
/transcript_id="NM_001180165.1"
/db_xref="GI:296143262"
/db_xref="GeneID:851452"
CDS complement(270222..271901)
/gene="PHO2"
/locus_tag="YDL106C"
/gene_synonym="BAS2; GRF10"
/note="Homeobox transcription factor; regulatory targets
include genes involved in phosphate metabolism; binds
cooperatively with Pho4p to the PHO5 promoter;
phosphorylation of Pho2p facilitates interaction with
Pho4p"
/codon_start=1
/product="Pho2p"
/protein_id="NP_010177.1"
/db_xref="GI:6320097"
/db_xref="SGD:S000002264"
/db_xref="GeneID:851452"
/translation="MMEEFSYDHDFNTHFATDLDYLQHDQQQQQQQQHDQQHNQQQQP
QPQPIQTQNLEHDHDQHTNDMSASSNASDSGPQRPKRTRAKGEALDVLKRKFEINPTP
SLVERKKISDLIGMPEKNVRIWFQNRRAKLRKKQHGSNKDTIPSSQSRDIANDYDRGS
TDNNLVTTTSTSSIFHDEDLTFFDRIPLNSNNNYYFFDICSITVGSWNRMKSGALQRR
NFQSIKELRNLSPIKINNIMSNATDLMVLISKKNSEINYFFSAMANNTKILFRIFFPL
SSVTNCSLTLETDDDIINSNNTSDKNNSNTNNDDDNDDNSNEDNDNSSEDKRNAKDNF
GELKLTVTRSPTFAVYFLNNAPDEDPNLNNQWSICDDFSEGRQVNDAFVGGSNIPHTL
KGLQKSLRFMNSLILDYKSSNEILPTINTAIPTAAVPQQNIAPPFLNTNSSATDSNPN
TNLEDSLFFDHDLLSSSITNTNNGQGSNNGRQASKDDTLNLLDTTVNSNNNHNANNEE
NHLAQEHLSNDADIVANPNDHLLSLPTDSELPNTPDFLKNTNELTDEHRWI"
gene 272389..273597
/gene="NSE4"
/locus_tag="YDL105W"
/gene_synonym="QRI2"
/db_xref="GeneID:851453"
mRNA 272389..273597
/gene="NSE4"
/locus_tag="YDL105W"
/gene_synonym="QRI2"
/product="Nse4p"
/transcript_id="NM_001180164.1"
/db_xref="GI:296143263"
/db_xref="GeneID:851453"
CDS 272389..273597
/gene="NSE4"
/locus_tag="YDL105W"
/gene_synonym="QRI2"
/note="Component of the SMC5-SMC6 complex; this complex
plays a key role in the removal of X-shaped DNA structures
that arise between sister chromatids during DNA
replication and repair"
/codon_start=1
/product="Nse4p"
/protein_id="NP_010178.1"
/db_xref="GI:6320098"
/db_xref="SGD:S000002263"
/db_xref="GeneID:851453"
/translation="MSSTVISRKRRNSTVTEPDSSGETRKQKKSRSDEKSSSSKDGDP
QLEFKVLQGYRDLESEMHKGRAQVTRTGDIGVAMDNLNAVDSLFNKVIGIKNNGLFAH
DARAMVSISELAQISVRNLKFDDSRSMVNLENIVNSLKRYMLKEHFKLNNIAENRNDL
TLAADEQSAADQQEESDGDIDRTPDDNHTDKATSSFKATSMRHSYLQQFSHYNEFSQF
NWFRIGALYNTISKNAPITDHLMGPLSIEKKPRVLTQRRRNNDQVGEKITAEKITQHS
LNSTQQETTPEQVKKCFKKLSKKLGPEGSINLFKFIIDPNSFSRSIENLFYTSFLIKE
GKLLMEHDEEGLPTIKIKQSISHTDSRSKEIERQRRRAAHQNHIIFQMDMPTWRKLIK
KYNITSPFLD"
gene complement(273653..274876)
/gene="QRI7"
/locus_tag="YDL104C"
/db_xref="GeneID:851454"
mRNA complement(273653..274876)
/gene="QRI7"
/locus_tag="YDL104C"
/product="Qri7p"
/transcript_id="NM_001180163.1"
/db_xref="GI:296143264"
/db_xref="GeneID:851454"
CDS complement(273653..274876)
/gene="QRI7"
/locus_tag="YDL104C"
/EC_number="3.4.24.-"
/note="Highly conserved mitochondrial protein, essential
for t6A modification of mitochondrial tRNAs that decode
ANN codons; similar to Kae1p and E. coli YgjD, both of
which are also required for tRNA t6A modification"
/codon_start=1
/product="Qri7p"
/protein_id="NP_010179.1"
/db_xref="GI:6320099"
/db_xref="SGD:S000002262"
/db_xref="GeneID:851454"
/translation="MISIKGTGRFLLDNYRIWQRRAFNRPIQLRKGYKVLAIETSCDD
TCVSVLDRFSKSAAPNVLANLKDTLDSIDEGGIIPTKAHIHHQARIGPLTERALIESN
AREGIDLICVTRGPGMPGSLSGGLDFAKGLAVAWNKPLIGVHHMLGHLLIPRMGTNGK
VPQFPFVSLLVSGGHTTFVLSRAIDDHEILCDTIDIAVGDSLDKCGRELGFKGTMIAR
EMEKFINQDINDQDFALKLEMPSPLKNSASKRNMLSFSFSAFITALRTNLTKLGKTEI
QELPEREIRSIAYQVQESVFDHIINKLKHVLKSQPEKFKNVREFVCSGGVSSNQRLRT
KLETELGTLNSTSFFNFYYPPMDLCSDNSIMIGWAGIEIWESLRLVSDLDICPIRQWP
LNDLLSVDGWRTDQL"
gene complement(275148..276581)
/gene="QRI1"
/locus_tag="YDL103C"
/gene_synonym="UAP1"
/db_xref="GeneID:851455"
mRNA complement(275148..276581)
/gene="QRI1"
/locus_tag="YDL103C"
/gene_synonym="UAP1"
/product="UDP-N-acetylglucosamine diphosphorylase"
/transcript_id="NM_001180162.1"
/db_xref="GI:296143265"
/db_xref="GeneID:851455"
CDS complement(275148..276581)
/gene="QRI1"
/locus_tag="YDL103C"
/gene_synonym="UAP1"
/EC_number="2.7.7.23"
/note="UDP-N-acetylglucosamine pyrophosphorylase;
catalyzes the formation of UDP-N-acetylglucosamine
(UDP-GlcNAc), which is important in cell wall
biosynthesis, protein N-glycosylation, and GPI anchor
biosynthesis; protein abundance increases in response to
DNA replication stress"
/codon_start=1
/product="UDP-N-acetylglucosamine diphosphorylase"
/protein_id="NP_010180.1"
/db_xref="GI:6320100"
/db_xref="SGD:S000002261"
/db_xref="GeneID:851455"
/translation="MTDTKQLFIEAGQSQLFHNWESLSRKDQEELLSNLEQISSKRSP
AKLLEDCQNAIKFSLANSSKDTGVEISPLPPTSYESLIGNSKKENEYWRLGLEAIGKG
EVAVILMAGGQGTRLGSSQPKGCYDIGLPSKKSLFQIQAEKLIRLQDMVKDKKVEIPW
YIMTSGPTRAATEAYFQEHNYFGLNKEQITFFNQGTLPAFDLTGKHFLMKDPVNLSQS
PDGNGGLYRAIKENKLNEDFDRRGIKHVYMYCVDNVLSKIADPVFIGFAIKHGFELAT
KAVRKRDAHESVGLIATKNEKPCVIEYSEISNELAEAKDKDGLLKLRAGNIVNHYYLV
DLLKRDLDQWCENMPYHIAKKKIPAYDSVTGKYTKPTEPNGIKLEQFIFDVFDTVPLN
KFGCLEVDRCKEFSPLKNGPGSKNDNPETSRLAYLKLGTSWLEDAGAIVKDGVLVEVS
SKLSYAGENLSQFKGKVFDRSGIVLEK"
gene 276872..280165
/gene="POL3"
/locus_tag="YDL102W"
/gene_synonym="CDC2; HPR6; TEX1"
/db_xref="GeneID:851456"
mRNA 276872..280165
/gene="POL3"
/locus_tag="YDL102W"
/gene_synonym="CDC2; HPR6; TEX1"
/product="Pol3p"
/transcript_id="NM_001180161.2"
/db_xref="GI:330443502"
/db_xref="GeneID:851456"
CDS 276872..280165
/gene="POL3"
/locus_tag="YDL102W"
/gene_synonym="CDC2; HPR6; TEX1"
/EC_number="2.7.7.7"
/note="Catalytic subunit of DNA polymerase delta; required
for chromosomal DNA replication during mitosis and
meiosis, intragenic recombination, repair of double strand
DNA breaks, and DNA replication during nucleotide excision
repair (NER)"
/codon_start=1
/product="Pol3p"
/protein_id="NP_010181.2"
/db_xref="GI:330443503"
/db_xref="SGD:S000002260"
/db_xref="GeneID:851456"
/translation="MSEKRSLPMVDVKIDDEDTPQLEKKIKRQSIDHGVGSEPVSTIE
IIPSDSFRKYNSQGFKAKDTDLMGTQLESTFEQELSQMEHDMADQEEHDLSSFERKKL
PTDFDPSLYDISFQQIDAEQSVLNGIKDENTSTVVRFFGVTSEGHSVLCNVTGFKNYL
YVPAPNSSDANDQEQINKFVHYLNETFDHAIDSIEVVSKQSIWGYSGDTKLPFWKIYV
TYPHMVNKLRTAFERGHLSFNSWFSNGTTTYDNIAYTLRLMVDCGIVGMSWITLPKGK
YSMIEPNNRVSSCQLEVSINYRNLIAHPAEGDWSHTAPLRIMSFDIECAGRIGVFPEP
EYDPVIQIANVVSIAGAKKPFIRNVFTLNTCSPITGSMIFSHATEEEMLSNWRNFIIK
VDPDVIIGYNTTNFDIPYLLNRAKALKVNDFPYFGRLKTVKQEIKESVFSSKAYGTRE
TKNVNIDGRLQLDLLQFIQREYKLRSYTLNAVSAHFLGEQKEDVHYSIISDLQNGDSE
TRRRLAVYCLKDAYLPLRLMEKLMALVNYTEMARVTGVPFSYLLARGQQIKVVSQLFR
KCLEIDTVIPNMQSQASDDQYEGATVIEPIRGYYDVPIATLDFNSLYPSIMMAHNLCY
TTLCNKATVERLNLKIDEDYVITPNGDYFVTTKRRRGILPIILDELISARKRAKKDLR
DEKDPFKRDVLNGRQLALKISANSVYGFTGATVGKLPCLAISSSVTAYGRTMILKTKT
AVQEKYCIKNGYKHDAVVVYGDTDSVMVKFGTTDLKEAMDLGTEAAKYVSTLFKHPIN
LEFEKAYFPYLLINKKRYAGLFWTNPDKFDKLDQKGLASVRRDSCSLVSIVMNKVLKK
ILIERNVDGALAFVRETINDILHNRVDISKLIISKTLAPNYTNPQPHAVLAERMKRRE
GVGPNVGDRVDYVIIGGNDKLYNRAEDPLFVLENNIQVDSRYYLTNQLQNPIISIVAP
IIGDKQANGMFVVKSIKINTGSQKGGLMSFIKKVEACKSCKGPLRKGEGPLCSNCLAR
SGELYIKALYDVRDLEEKYSRLWTQCQRCAGNLHSEVLCSNKNCDIFYMRVKVKKELQ
EKVEQLSKW"
gene complement(280307..281848)
/gene="DUN1"
/locus_tag="YDL101C"
/db_xref="GeneID:851457"
mRNA complement(280307..281848)
/gene="DUN1"
/locus_tag="YDL101C"
/product="Dun1p"
/transcript_id="NM_001180160.1"
/db_xref="GI:296143267"
/db_xref="GeneID:851457"
CDS complement(280307..281848)
/gene="DUN1"
/locus_tag="YDL101C"
/EC_number="2.7.11.1"
/note="Cell-cycle checkpoint serine-threonine kinase
required for DNA damage-induced transcription of certain
target genes, phosphorylation of Rad55p and Sml1p, and
transient G2/M arrest after DNA damage; also regulates
postreplicative DNA repair"
/codon_start=1
/product="Dun1p"
/protein_id="NP_010182.1"
/db_xref="GI:6320102"
/db_xref="SGD:S000002259"
/db_xref="GeneID:851457"
/translation="MSLSTKREHSGDVTDSSFKRQQRSNKPSSEYTCLGHLVNLIPGK
EQKVEITNRNVTTIGRSRSCDVILSEPDISTFHAEFHLLQMDVDNFQRNLINVIDKSR
NGTFINGNRLVKKDYILKNGDRIVFGKSCSFLFKYASSSSTDIENDDEKVSSESRSYK
NDDEVFKKPQISATSSQNATTSAAIRKLNKTRPVSFFDKYLLGKELGAGHYALVKEAK
NKKTGQQVAVKIFHAQQNDDQKKNKQFREETNILMRVQHPNIVNLLDSFVEPISKSQI
QKYLVLEKIDDGELFERIVRKTCLRQDESKALFKQLLTGLKYLHEQNIIHRDIKPENI
LLNITRRENPSQVQLGPWDEDEIDIQVKIADFGLAKFTGEMQFTNTLCGTPSYVAPEV
LTKKGYTSKVDLWSAGVILYVCLCGFPPFSDQLGPPSLKEQILQAKYAFYSPYWDKID
DSVLHLISNLLVLNPDERYNIDEALNHPWFNDIQQQSSVSLELQRLQITDNKIPKTYS
ELSCL"
gene complement(282112..283176)
/gene="GET3"
/locus_tag="YDL100C"
/gene_synonym="ARR4"
/db_xref="GeneID:851458"
mRNA complement(282112..283176)
/gene="GET3"
/locus_tag="YDL100C"
/gene_synonym="ARR4"
/product="guanine nucleotide exchange factor GET3"
/transcript_id="NM_001180159.1"
/db_xref="GI:296143268"
/db_xref="GeneID:851458"
CDS complement(282112..283176)
/gene="GET3"
/locus_tag="YDL100C"
/gene_synonym="ARR4"
/EC_number="3.6.3.16"
/note="Guanine nucleotide exchange factor for Gpa1p;
amplifies G protein signaling; subunit of the GET complex,
which is involved in Golgi to ER trafficking and insertion
of proteins into the ER membrane; has low-level ATPase
activity; protein abundance increases in response to DNA
replication stress"
/codon_start=1
/product="guanine nucleotide exchange factor GET3"
/protein_id="NP_010183.1"
/db_xref="GI:6320103"
/db_xref="SGD:S000002258"
/db_xref="GeneID:851458"
/translation="MDLTVEPNLHSLITSTTHKWIFVGGKGGVGKTTSSCSIAIQMAL
SQPNKQFLLISTDPAHNLSDAFGEKFGKDARKVTGMNNLSCMEIDPSAALKDMNDMAV
SRANNNGSDGQGDDLGSLLQGGALADLTGSIPGIDEALSFMEVMKHIKRQEQGEGETF
DTVIFDTAPTGHTLRFLQLPNTLSKLLEKFGEITNKLGPMLNSFMGAGNVDISGKLNE
LKANVETIRQQFTDPDLTTFVCVCISEFLSLYETERLIQELISYDMDVNSIIVNQLLF
AENDQEHNCKRCQARWKMQKKYLDQIDELYEDFHVVKMPLCAGEIRGLNNLTKFSQFL
NKEYNPITDGKVIYELEDKE"
gene 283419..284444
/gene="BUG1"
/locus_tag="YDL099W"
/db_xref="GeneID:851459"
mRNA 283419..284444
/gene="BUG1"
/locus_tag="YDL099W"
/product="Bug1p"
/transcript_id="NM_001180158.1"
/db_xref="GI:296143269"
/db_xref="GeneID:851459"
CDS 283419..284444
/gene="BUG1"
/locus_tag="YDL099W"
/note="Cis-golgi localized protein involved in ER to Golgi
transport; forms a complex with the mammalian GRASP65
homolog, Grh1p; mutants are compromised for the fusion of
ER-derived vesicles with Golgi membranes"
/codon_start=1
/product="Bug1p"
/protein_id="NP_010184.1"
/db_xref="GI:6320104"
/db_xref="SGD:S000002257"
/db_xref="GeneID:851459"
/translation="MSEQESDEVKRMKQLEEARKRVEELKKKKNKKNKGKKNKNSSAT
GSIGSETPDLEGTPGEESTQEETVKANSTKSENNDQNDVDEESEEKEIEQVKSDPSGT
TEKDIEEINSTSSNVGKDDAENTKKEEVQEVIKNNNDEQTADAGKTIEPQEEKKIVQT
QEGNEPSNTSEAADDLFANDGNEESDFLTTIKKQKEEDELTKLRAENEKLTQENKQLK
FLNMENETTVDDLQDQLQEKEDIINGLQNDLQTARDELIAAVEKLKLAEAKAARNTTA
TPIQFADFNTSSNNLTPSQSVTNSGTQVAHGNNMEVDRVMLNKWRQWNVDMTTWRSIG
SGPIMEF"
gene complement(284581..285165)
/gene="SNU23"
/locus_tag="YDL098C"
/db_xref="GeneID:851460"
mRNA complement(284581..285165)
/gene="SNU23"
/locus_tag="YDL098C"
/product="Snu23p"
/transcript_id="NM_001180157.1"
/db_xref="GI:296143270"
/db_xref="GeneID:851460"
CDS complement(284581..285165)
/gene="SNU23"
/locus_tag="YDL098C"
/note="Component of U4/U6.U5 snRNP involved in mRNA
splicing via spliceosome"
/codon_start=1
/product="Snu23p"
/protein_id="NP_010185.1"
/db_xref="GI:6320105"
/db_xref="SGD:S000002256"
/db_xref="GeneID:851460"
/translation="MSNFGRRTWDREEYAEQARSGYDDRSLKATLTPIELQALKSKYT
NYDHLIKGSLKDLNKRKLTANTESLSSFKRGKKFGFYCDICNLTFKDTLQYIDHLNHK
VHAIKFENLFDEPLIIDIRDNDDVPQEEFELCYHNLIKDFVEVRSMETQSKRKRLLDT
DVEKAKKVATKPSIESESKVSQMMGFSNFATSKK"
gene complement(285391..286695)
/gene="RPN6"
/locus_tag="YDL097C"
/gene_synonym="NAS4"
/db_xref="GeneID:851461"
mRNA complement(285391..286695)
/gene="RPN6"
/locus_tag="YDL097C"
/gene_synonym="NAS4"
/product="proteasome regulatory particle lid subunit RPN6"
/transcript_id="NM_001180156.1"
/db_xref="GI:296143271"
/db_xref="GeneID:851461"
CDS complement(285391..286695)
/gene="RPN6"
/locus_tag="YDL097C"
/gene_synonym="NAS4"
/note="Essential, non-ATPase regulatory subunit of the 26S
proteasome lid; required for the assembly and activity of
the 26S proteasome; the human homolog (S9 protein)
partially rescues Rpn6p depletion; protein abundance
increases in response to DNA replication stress"
/codon_start=1
/product="proteasome regulatory particle lid subunit RPN6"
/protein_id="NP_010186.1"
/db_xref="GI:6320106"
/db_xref="SGD:S000002255"
/db_xref="GeneID:851461"
/translation="MSLPGSKLEEARRLVNEKQYNEAEQVYLSLLDKDSSQSSAAAGA
SVDDKRRNEQETSILELGQLYVTMGAKDKLREFIPHSTEYMMQFAKSKTVKVLKTLIE
KFEQVPDSLDDQIFVCEKSIEFAKREKRVFLKHSLSIKLATLHYQKKQYKDSLALIND
LLREFKKLDDKPSLVDVHLLESKVYHKLRNLAKSKASLTAARTAANSIYCPTQTVAEL
DLMSGILHCEDKDYKTAFSYFFESFESYHNLTTHNSYEKACQVLKYMLLSKIMLNLID
DVKNILNAKYTKETYQSRGIDAMKAVAEAYNNRSLLDFNTALKQYEKELMGDELTRSH
FNALYDTLLESNLCKIIEPFECVEISHISKIIGLDTQQVEGKLSQMILDKIFYGVLDQ
GNGWLYVYETPNQDATYDSALELVGQLNKVVDQLFEKASVLY"
gene 287059..289512
/gene="PMT1"
/locus_tag="YDL095W"
/db_xref="GeneID:851462"
mRNA 287059..289512
/gene="PMT1"
/locus_tag="YDL095W"
/product="Pmt1p"
/transcript_id="NM_001180154.1"
/db_xref="GI:296143272"
/db_xref="GeneID:851462"
CDS 287059..289512
/gene="PMT1"
/locus_tag="YDL095W"
/EC_number="2.4.1.109"
/note="Protein O-mannosyltransferase of the ER membrane;
transfers mannose from dolichyl phosphate-D-mannose to
protein serine and threonine residues; 1 of 7 related
proteins involved in O-glycosylation which is essential
for cell wall rigidity; involved in ER quality control;
amino terminus faces cytoplasm, carboxyl terminus faces ER
lumen"
/codon_start=1
/product="Pmt1p"
/protein_id="NP_010188.1"
/db_xref="GI:6320107"
/db_xref="SGD:S000002253"
/db_xref="GeneID:851462"
/translation="MSEEKTYKRVEQDDPVPELDIKQGPVRPFIVTDPSAELASLRTM
VTLKEKLLVACLAVFTAVIRLHGLAWPDSVVFDEVHFGGFASQYIRGTYFMDVHPPLA
KMLYAGVASLGGFQGDFDFENIGDSFPSTTPYVLMRFFSASLGALTVILMYMTLRYSG
VRMWVALMSAICFAVENSYVTISRYILLDAPLMFFIAAAVYSFKKYEMYPANSLNAYK
SLLATGIALGMASSSKWVGLFTVTWVGLLCIWRLWFMIGDLTKSSKSIFKVAFAKLAF
LLGVPFALYLVFFYIHFQSLTLDGDGASFFSPEFRSTLKNNKIPQNVVADVGIGSIIS
LRHLSTMGGYLHSHSHNYPAGSEQQQSTLYPHMDANNDWLLELYNAPGESLTTFQNLT
DGTKVRLFHTVTRCRLHSHDHKPPVSESSDWQKEVSCYGYSGFDGDANDDWVVEIDKK
NSAPGVAQERVIALDTKFRLRHAMTGCYLFSHEVKLPAWGFEQQEVTCASSGRHDLTL
WYVENNSNPLLPEDTKRISYKPASFISKFIESHKKMWHINKNLVEPHVYESQPTSWPF
LLRGISYWGENNRNVYLLGNAIVWWAVTAFIGIFGLIVITELFSWQLGKPILKDSKVV
NFHVQVIHYLLGFAVHYAPSFLMQRQMFLHHYLPAYYFGILALGHALDIIVSYVFRSK
RQMGYAVVITFLAASVYFFKSFSPIIYGTPWTQELCQKSQWLSGWDYNCNTYFSSLEE
YKNQTLTKRESQPAATSTVEEITIEGDGPSYEDLMNEDGKKIFKDTEGNELDPEVVKK
MLEEEGANILKVEKRAVLE"
gene 289909..292140
/gene="PMT5"
/locus_tag="YDL093W"
/db_xref="GeneID:851464"
mRNA 289909..292140
/gene="PMT5"
/locus_tag="YDL093W"
/product="Pmt5p"
/transcript_id="NM_001180152.1"
/db_xref="GI:296143273"
/db_xref="GeneID:851464"
CDS 289909..292140
/gene="PMT5"
/locus_tag="YDL093W"
/EC_number="2.4.1.109"
/note="Protein O-mannosyltransferase, transfers mannose
residues from dolichyl phosphate-D-mannose to protein
serine/threonine residues; acts in a complex with Pmt3p,
can instead interact with Pmt2p in some conditions; target
for new antifungals"
/codon_start=1
/product="Pmt5p"
/protein_id="NP_010190.1"
/db_xref="GI:6320109"
/db_xref="SGD:S000002251"
/db_xref="GeneID:851464"
/translation="MNKEHLLKVDPIPDVTIKRGPLRSFLITKPCDNLSSLRTVTSSK
EKLLVGCLLIFTAIVRLHNISLPNSVVFGENEVGTFVSQYVNNIFFTDVHPPLVAMLY
ATVSSVFGYKGLFNYGNIGTEYTANVPYVAMRFFSATLGIVSVLVLYLTLRVSGVKIA
VAAICAVCFAIENSFVTLSRFTLIEGPFVFFMACAVYFFRRSELYLPNSCKANKSLLA
ASIALGFAVSSKWAGLFTIAWAGIIVLWRVWFMIGDLSRPIGSSIKYMAFQFTCLLAI
PAFIYFLIFSVHIKTLNVNGISSSFFPAEFRKTLKYNNVIKETVAEVAVGSAVSLNHV
GTAGGYLHSHLHNYPAGSMQQQVTLYPHIDQNNKWIIELAEHPNENVTSFQNLTDGTI
IKLRQLKNGCRLHSHDHKPPVSQNADWQKEVSCYGYEGFEGDINDDWIIEIDKKRSEP
GPAQEHIRAIETKFRLKHYLTGCYLFSHPEKLPEWGFGQQEVTCAYFAREDLTSWYIE
ENENEISLPNPEKVSYKKMSFWQKFVAIHKFMFYLNNYMDTSHAYSSEPKTWPLMLRG
IDFWNENGREVYFLGNAVLWWSVTAFICTFIIGVAVELLAWKLGVNILRDKHIINFHY
QVFQYLLGFAAHYFPYFFVGQKLFLYDYLPAYYFGILAFGHALDLISTYISNKRNNTG
YIVVAIFMVVCFYFFSEHSPLIYATGWSSNLCKRSKWLGSWDFYCNSLLLSDSHYELN
AES"
gene 292781..293221
/gene="SRP14"
/locus_tag="YDL092W"
/db_xref="GeneID:851466"
mRNA 292781..293221
/gene="SRP14"
/locus_tag="YDL092W"
/product="Srp14p"
/transcript_id="NM_001180151.1"
/db_xref="GI:296143274"
/db_xref="GeneID:851466"
CDS 292781..293221
/gene="SRP14"
/locus_tag="YDL092W"
/note="Signal recognition particle (SRP) subunit,
interacts with the RNA component of SRP to form the Alu
domain, which is the region of SRP responsible for arrest
of nascent chain elongation during membrane targeting;
homolog of mammalian SRP14"
/codon_start=1
/product="Srp14p"
/protein_id="NP_010191.1"
/db_xref="GI:6320111"
/db_xref="SGD:S000002250"
/db_xref="GeneID:851466"
/translation="MANTGCLSPGAFLSKVPEFFQTANEKHITVRLTAKRLIEHDPVE
GNLEFDSTNHPDYDVSKKASEISVSSRSDREYPLLIRMSYGSHDKKTKCSTVVKASEL
DQFWQEYSSVFKGGMQNLIKKKKKKSKNGTISKTGKKNKVAKKN"
gene complement(293392..294759)
/gene="UBX3"
/locus_tag="YDL091C"
/db_xref="GeneID:851467"
mRNA complement(293392..294759)
/gene="UBX3"
/locus_tag="YDL091C"
/product="Ubx3p"
/transcript_id="NM_001180150.1"
/db_xref="GI:296143275"
/db_xref="GeneID:851467"
CDS complement(293392..294759)
/gene="UBX3"
/locus_tag="YDL091C"
/note="UBX (ubiquitin regulatory X) domain-containing
protein that interacts with Cdc48p, green fluorescent
protein (GFP)-fusion protein localizes to the cytoplasm in
a punctate pattern"
/codon_start=1
/product="Ubx3p"
/protein_id="NP_010192.1"
/db_xref="GI:6320112"
/db_xref="SGD:S000002249"
/db_xref="GeneID:851467"
/translation="MDIFRHTFGNNDDSFIRIPGAFREEPPADLNGRTEDQNSNTNEP
TQSRDGRLKSILHFLFQAPLIVLYYLLNFIVRSSRLLKPLLRLHGFYQRKHNRLLDHS
SQLHRLLENLENEAQAVTCSEGNGNNDDGSNTDSTSNNESSGVQFSFGSLYNPENGTF
SKSIMQNSYTELLDACSEQVKFGVIYLHDPLLDNHMDYVNKILCSEAFVNMIRKYQVL
LWYGDVTTSEGLQVSNALKIRQYPLLGIISLKAEKKIELIARVEGSISNYKAQDLEAI
FSKNYSRLIQLRQQRQNIEMQRLIRQQQDSRYQDSLRRDQQRESERLEQTQREQMERE
HQRIENQWLLWRKSQLKPEPSSDKDASKVAIRLENGQRLVRKFDASLPTEEIYAFVEL
QLHDMLNSENDTLPVYQPANYQHQYSFKLITPVPRRELDLSTKISDVSGIYPSGNIVM
ERLDE"
gene complement(295034..296329)
/gene="RAM1"
/locus_tag="YDL090C"
/gene_synonym="DPR1; FUS8; SCG2; SGP2; STE16"
/db_xref="GeneID:851468"
mRNA complement(295034..296329)
/gene="RAM1"
/locus_tag="YDL090C"
/gene_synonym="DPR1; FUS8; SCG2; SGP2; STE16"
/product="protein farnesyltransferase"
/transcript_id="NM_001180149.1"
/db_xref="GI:296143276"
/db_xref="GeneID:851468"
CDS complement(295034..296329)
/gene="RAM1"
/locus_tag="YDL090C"
/gene_synonym="DPR1; FUS8; SCG2; SGP2; STE16"
/EC_number="2.5.1.58"
/note="Beta subunit of the CAAX farnesyltransferase
(FTase) that prenylates the a-factor mating pheromone and
Ras proteins; required for the membrane localization of
Ras proteins and a-factor; homolog of the mammalian FTase
beta subunit"
/codon_start=1
/product="protein farnesyltransferase"
/protein_id="NP_010193.1"
/db_xref="GI:6320113"
/db_xref="SGD:S000002248"
/db_xref="GeneID:851468"
/translation="MRQRVGRSIARAKFINTALLGRKRPVMERVVDIAHVDSSKAIQP
LMKELETDTTEARYKVLQSVLEIYDDEKNIEPALTKEFHKMYLDVAFEISLPPQMTAL
DASQPWMLYWIANSLKVMDRDWLSDDTKRKIVDKLFTISPSGGPFGGGPGQLSHLAST
YAAINALSLCDNIDGCWDRIDRKGIYQWLISLKEPNGGFKTCLEVGEVDTRGIYCALS
IATLLNILTEELTEGVLNYLKNCQNYEGGFGSCPHVDEAHGGYTFCATASLAILRSMD
QINVEKLLEWSSARQLQEERGFCGRSNKLVDGCYSFWVGGSAAILEAFGYGQCFNKHA
LRDYILYCCQEKEQPGLRDKPGAHSDFYHTNYCLLGLAVAESSYSCTPNDSPHNIKCT
PDRLIGSSKLTDVNPVYGLPIENVRKIIHYFKSNLSSPS"
gene 296820..298274
/gene="NUR1"
/locus_tag="YDL089W"
/db_xref="GeneID:851469"
mRNA 296820..298274
/gene="NUR1"
/locus_tag="YDL089W"
/product="Nur1p"
/transcript_id="NM_001180148.1"
/db_xref="GI:296143277"
/db_xref="GeneID:851469"
CDS 296820..298274
/gene="NUR1"
/locus_tag="YDL089W"
/note="hypothetical protein; interacts with Csm1p, Lrs4p;
required for rDNA repeat stability; null mutant causes
increase in unequal sister-chromatid exchange; GFP-fusion
protein localizes to the nuclear periphery, possible
Cdc28p substrate"
/codon_start=1
/product="Nur1p"
/protein_id="NP_010194.1"
/db_xref="GI:6320114"
/db_xref="SGD:S000002247"
/db_xref="GeneID:851469"
/translation="MGSNDLINEAYDDSEVVGEERESKSAWMKRWYQLLTSPLDLQLV
INEKLEMINWDAYAKSLAKPLGNFLTILFFIIRLLQDNLIKPNYYKLNVKSGAFDLSK
SNKLKEFDYLWEISSSFQNNNQFYAFQSWYFVTLRFLNNLFRFTIFILLSLNLYVSCK
FMFGYFKTYNLFHLKKEFNSPNLTKHNLKDLSKEYYEDIYKQSLWSMLKHFFRGSRDD
GPHVNQNEDEIFFQLRKWIPTNFMINLFVSFSPTAIVFLSFSDVSFTSAIAIVFHQYI
LDYIITKRFQRSVDDDLILSSAALQEYEDKHIMARINQCSNIDTLSSAMGTRSKTPRI
FTTHSLCGEEIREVYNYEKREFEALPKMTESVPGSRETRIKDYGGISQVSDHQSHPIG
FHYSPRMSPYYRDKVLDNNLAQSSSNENLEKGGAYLPNQDQNRPSKSLSPLRKTPLSA
RQKRFEGSEFNVLNKNDINSILRSPKKKKNYHKR"
gene complement(298417..300003)
/gene="ASM4"
/locus_tag="YDL088C"
/gene_synonym="NUP59"
/db_xref="GeneID:851470"
mRNA complement(298417..300003)
/gene="ASM4"
/locus_tag="YDL088C"
/gene_synonym="NUP59"
/product="Asm4p"
/transcript_id="NM_001180147.1"
/db_xref="GI:296143278"
/db_xref="GeneID:851470"
CDS complement(298417..300003)
/gene="ASM4"
/locus_tag="YDL088C"
/gene_synonym="NUP59"
/note="FG-nucleoporin component of central core of nuclear
pore complex (NPC); contributes directly to
nucleocytoplasmic transport; induces membrane tubulation,
which may contribute to nuclear pore assembly; ASM4 has a
paralog, NUP53, that arose from the whole genome
duplication"
/codon_start=1
/product="Asm4p"
/protein_id="NP_010195.1"
/db_xref="GI:6320115"
/db_xref="SGD:S000002246"
/db_xref="GeneID:851470"
/translation="MFGIRSGNNNGGFTNLTSQAPQTTQMFQSQSQLQPQPQPQPQQQ
QQHLQFNGSSDASSLRFGNSLSNTVNANNYSSNIGNNSINNNNIKNGTNNISQHGQGN
NPSWVNNPKKRFTPHTVIRRKTTKQNSSSDINQNDDSSSMNATMRNFSKQNQDSKHNE
RNKSAANNDINSLLSNFNDIPPSVTLQDWQREDEFGSIPSLTTQFVTDKYTAKKTNRS
AYDSKNTPNVFDKDSYVRIANIEQNHLDNNYNTAETNNKVHETSSKSSSLSAIIVFGY
PESISNELIEHFSHFGHIMEDFQVLRLGRGINPNTFRIFHNHDTGCDENDSTVNKSIT
LKGRNNESNNKKYPIFTGESWVKLTYNSPSSALRALQENGTIFRGSLIGCIPYSKNAV
EQLAGCKIDNVDDIGEFNVSMYQNSSTSSTSNTPSPPNVIITDGTLLREDDNTPAGHA
GNPTNISSPIVANSPNKRLDVIDGKLPFMQNAGPNSNIPNLLRNLESKMRQQEAKYRN
NEPAGFTHKLSNWLFGWNDL"
gene complement(300214..300999)
/gene="LUC7"
/locus_tag="YDL087C"
/gene_synonym="EPE1; EXM2"
/db_xref="GeneID:851471"
mRNA complement(300214..300999)
/gene="LUC7"
/locus_tag="YDL087C"
/gene_synonym="EPE1; EXM2"
/product="Luc7p"
/transcript_id="NM_001180146.1"
/db_xref="GI:296143279"
/db_xref="GeneID:851471"
CDS complement(300214..300999)
/gene="LUC7"
/locus_tag="YDL087C"
/gene_synonym="EPE1; EXM2"
/note="Essential protein associated with the U1 snRNP
complex; splicing factor involved in recognition of 5'
splice site; contains two zinc finger motifs; N-terminal
zinc finger binds pre-mRNA"
/codon_start=1
/product="Luc7p"
/protein_id="NP_010196.1"
/db_xref="GI:6320116"
/db_xref="SGD:S000002245"
/db_xref="GeneID:851471"
/translation="MSTMSTPAAEQRKLVEQLMGRDFSFRHNRYSHQKRDLGLHDPKI
CKSYLVGECPYDLFQGTKQSLGKCPQMHLTKHKIQYEREVKQGKTFPEFEREYLAILS
RFVNECNGQISVALQNLKHTAEERMKIQQVTEELDVLDVRIGLMGQEIDSLIRADEVS
MGMLQSVKLQELISKRKEVAKRVRNITENVGQSAQQKLQVCEVCGAYLSRLDTDRRLA
DHFLGKIHLGYVKMREDYDRLMKNNRTTNASKTATTLPGRRFV"
gene 301413..302234
/locus_tag="YDL086W"
/db_xref="GeneID:851472"
mRNA 301413..302234
/locus_tag="YDL086W"
/product="carboxymethylenebutenolidase"
/transcript_id="NM_001180145.1"
/db_xref="GI:296143280"
/db_xref="GeneID:851472"
CDS 301413..302234
/locus_tag="YDL086W"
/EC_number="3.1.1.45"
/note="Putative carboxymethylenebutenolidase; the
authentic, non-tagged protein is detected in highly
purified mitochondria in high-throughput studies; YDL086W
is not an essential gene"
/codon_start=1
/product="carboxymethylenebutenolidase"
/protein_id="NP_010197.1"
/db_xref="GI:6320117"
/db_xref="SGD:S000002244"
/db_xref="GeneID:851472"
/translation="MLITETFHDVQTSYGTTLRIYVYSPKIAGYPQAKFPGVILYSEI
YQVTGPVRRFGQRIASEGYVVVAPAIYHNFMGPEALPYDVQGTDIGNEYKIKKPLESY
DEDNKLCCDLLFQLPQFDGKRIGSTGMCLGGHLAFRALLDKRVTCATCFFPTDIHSRT
LGLGQNDNSLERVSKELGNNQEMVLIFGTADTHVDPQGRDLIRKTLRDHGVKFTFLEI
LAAQHAFIRDEFSKGRFDSAITQSCLGFLFEQFNRKLRIDLGEFVDDNTPLEHVC"
gene complement(302464..302670)
/locus_tag="YDL085C-A"
/db_xref="GeneID:851473"
mRNA complement(302464..302670)
/locus_tag="YDL085C-A"
/product="hypothetical protein"
/transcript_id="NM_001184455.1"
/db_xref="GI:296143281"
/db_xref="GeneID:851473"
CDS complement(302464..302670)
/locus_tag="YDL085C-A"
/note="hypothetical protein; green fluorescent protein
(GFP)-fusion protein localizes to the cytoplasm and
nucleus"
/codon_start=1
/product="hypothetical protein"
/protein_id="NP_075208.1"
/db_xref="GI:12621478"
/db_xref="SGD:S000007588"
/db_xref="GeneID:851473"
/translation="MARGNQRDLARQKNLKKQKDMAKNQKKSGDPKKRMESDAEILRQ
KQAAADARREAEKLEKLKAEKTRR"
gene 303211..304848
/gene="NDE2"
/locus_tag="YDL085W"
/gene_synonym="NDH2"
/db_xref="GeneID:851474"
mRNA 303211..304848
/gene="NDE2"
/locus_tag="YDL085W"
/gene_synonym="NDH2"
/product="NADH-ubiquinone reductase (H(+)-translocating)
NDE2"
/transcript_id="NM_001180144.1"
/db_xref="GI:296143282"
/db_xref="GeneID:851474"
CDS 303211..304848
/gene="NDE2"
/locus_tag="YDL085W"
/gene_synonym="NDH2"
/EC_number="1.6.5.3"
/note="Mitochondrial external NADH dehydrogenase,
catalyzes the oxidation of cytosolic NADH; Nde1p and Nde2p
are involved in providing the cytosolic NADH to the
mitochondrial respiratory chain"
/codon_start=1
/product="NADH-ubiquinone reductase (H(+)-translocating)
NDE2"
/protein_id="NP_010198.1"
/db_xref="GI:6320118"
/db_xref="SGD:S000002243"
/db_xref="GeneID:851474"
/translation="MLPRLGFARTARSIHRFKMTQISKPFFHSTEVGKPGPQQKLSKS
YTAVFKKWFVRGLKLTFYTTLAGTLYVSYELYKESNPPKQVPQSTAFANGLKKKELVI
LGTGWGAISLLKKLDTSLYNVTVVSPRSFFLFTPLLPSTPVGTIEMKSIVEPVRSIAR
RTPGEVHYIEAEALDVDPKAKKVMVQSVSEDEYFVSSLSYDYLVVSVGAKTTTFNIPG
VYGNANFLKEIEDAQNIRMKLMKTIEQASSFPVNDPERKRLLTFVVVGGGPTGVEFAA
ELQDYINQDLRKWMPDLSKEMKVILIEALPNILNMFDKTLIKYAEDLFARDEIDLQVN
TAVKVVEPTYIRTLQNGQTNTDIEYGMLVWATGNEPIDFSKTLMSRIPEQTNRRGLLI
NDKLELLGSENSIYAIGDCTAHTGFFPTAQVAHQEGEYLAKILDKKLQIEQLEWDMLN
STDETEVSRLQKEVNLRKSKLDKFNYKHMGALAYIGSETAIADLHMGDSSYQLKGMFA
FLFWKSAYLAMCLSIRNRILIAMDWTKVYFLGRDSSV"
gene 305237..306577
/gene="SUB2"
/locus_tag="YDL084W"
/db_xref="GeneID:851475"
mRNA 305237..306577
/gene="SUB2"
/locus_tag="YDL084W"
/product="Sub2p"
/transcript_id="NM_001180143.1"
/db_xref="GI:296143283"
/db_xref="GeneID:851475"
CDS 305237..306577
/gene="SUB2"
/locus_tag="YDL084W"
/EC_number="3.6.1.-"
/note="Component of the TREX complex required for nuclear
mRNA export; member of the DEAD-box RNA helicase
superfamily and is involved in early and late steps of
spliceosome assembly; homolog of the human splicing factor
hUAP56; relocalizes from nucleus to cytoplasm upon DNA
replication stress"
/codon_start=1
/product="Sub2p"
/protein_id="NP_010199.1"
/db_xref="GI:6320119"
/db_xref="SGD:S000002242"
/db_xref="GeneID:851475"
/translation="MSHEGEEDLLEYSDNEQEIQIDASKAAEAGETGAATSATEGDNN
NNTAAGDKKGSYVGIHSTGFKDFLLKPELSRAIIDCGFEHPSEVQQHTIPQSIHGTDV
LCQAKSGLGKTAVFVLSTLQQLDPVPGEVAVVVICNARELAYQIRNEYLRFSKYMPDV
KTAVFYGGTPISKDAELLKNKDTAPHIVVATPGRLKALVREKYIDLSHVKNFVIDECD
KVLEELDMRRDVQEIFRATPRDKQVMMFSATLSQEIRPICRRFLQNPLEIFVDDEAKL
TLHGLQQYYIKLEEREKNRKLAQLLDDLEFNQVIIFVKSTTRANELTKLLNASNFPAI
TVHGHMKQEERIARYKAFKDFEKRICVSTDVFGRGIDIERINLAINYDLTNEADQYLH
RVGRAGRFGTKGLAISFVSSKEDEEVLAKIQERFDVKIAEFPEEGIDPSTYLNN"
gene complement(306926..307789)
/gene="RPS16B"
/locus_tag="YDL083C"
/db_xref="GeneID:851476"
mRNA complement(join(306926..307333,307766..307789))
/gene="RPS16B"
/locus_tag="YDL083C"
/product="ribosomal 40S subunit protein S16B"
/transcript_id="NM_001180142.1"
/db_xref="GI:296143284"
/db_xref="GeneID:851476"
CDS complement(join(306926..307333,307766..307789))
/gene="RPS16B"
/locus_tag="YDL083C"
/note="Protein component of the small (40S) ribosomal
subunit; homologous to mammalian ribosomal protein S16 and
bacterial S9; RPS16B has a paralog, RPS16A, that arose
from the whole genome duplication"
/codon_start=1
/product="ribosomal 40S subunit protein S16B"
/protein_id="NP_010200.1"
/db_xref="GI:6320120"
/db_xref="SGD:S000002241"
/db_xref="GeneID:851476"
/translation="MSAVPSVQTFGKKKSATAVAHVKAGKGLIKVNGSPITLVEPEIL
RFKVYEPLLLVGLDKFSNIDIRVRVTGGGHVSQVYAIRQAIAKGLVAYHQKYVDEQSK
NELKKAFTSYDRTLLIADSRRPEPKKFGGKGARSRFQKSYR"
gene 308424..309388
/gene="RPL13A"
/locus_tag="YDL082W"
/db_xref="GeneID:851477"
mRNA join(308424..308427,308793..309388)
/gene="RPL13A"
/locus_tag="YDL082W"
/product="ribosomal 60S subunit protein L13A"
/transcript_id="NM_001180141.1"
/db_xref="GI:296143285"
/db_xref="GeneID:851477"
CDS join(308424..308427,308793..309388)
/gene="RPL13A"
/locus_tag="YDL082W"
/note="Ribosomal 60S subunit protein L13A; not essential
for viability; homologous to mammalian ribosomal protein
L13, no bacterial homolog; RPL13A has a paralog, RPL13B,
that arose from the whole genome duplication"
/codon_start=1
/product="ribosomal 60S subunit protein L13A"
/protein_id="NP_010201.1"
/db_xref="GI:6320121"
/db_xref="SGD:S000002240"
/db_xref="GeneID:851477"
/translation="MAISKNLPILKNHFRKHWQERVKVHFDQAGKKVSRRNARATRAA
KIAPRPLDLLRPVVRAPTVKYNRKVRAGRGFTLAEVKAAGLTAAYARTIGIAVDHRRQ
NRNQEIFDANVQRLKEYQSKIIVFPRNGKAPEAEQVLSAAATFPIAQPATDVEARAVQ
DNGESAFRTLRLARSEKKFRGIREKRAREKAEAEAEKKK"
gene complement(309802..310122)
/gene="RPP1A"
/locus_tag="YDL081C"
/gene_synonym="RPLA1"
/db_xref="GeneID:851478"
mRNA complement(309802..310122)
/gene="RPP1A"
/locus_tag="YDL081C"
/gene_synonym="RPLA1"
/product="ribosomal protein P1A"
/transcript_id="NM_001180140.1"
/db_xref="GI:296143286"
/db_xref="GeneID:851478"
CDS complement(309802..310122)
/gene="RPP1A"
/locus_tag="YDL081C"
/gene_synonym="RPLA1"
/note="Ribosomal stalk protein P1 alpha, involved in the
interaction between translational elongation factors and
the ribosome; accumulation of P1 in the cytoplasm is
regulated by phosphorylation and interaction with the P2
stalk component"
/codon_start=1
/product="ribosomal protein P1A"
/protein_id="NP_010202.1"
/db_xref="GI:6320122"
/db_xref="SGD:S000002239"
/db_xref="GeneID:851478"
/translation="MSTESALSYAALILADSEIEISSEKLLTLTNAANVPVENIWADI
FAKALDGQNLKDLLVNFSAGAAAPAGVAGGVAGGEAGEAEAEKEEEEAKEESDDDMGF
GLFD"
gene complement(310642..312471)
/gene="THI3"
/locus_tag="YDL080C"
/gene_synonym="KID1"
/db_xref="GeneID:851479"
mRNA complement(310642..312471)
/gene="THI3"
/locus_tag="YDL080C"
/gene_synonym="KID1"
/product="branched-chain-2-oxoacid decarboxylase THI3"
/transcript_id="NM_001180139.1"
/db_xref="GI:296143287"
/db_xref="GeneID:851479"
CDS complement(310642..312471)
/gene="THI3"
/locus_tag="YDL080C"
/gene_synonym="KID1"
/EC_number="4.1.1.72"
/EC_number="4.1.1.1"
/note="Probable alpha-ketoisocaproate decarboxylase, may
have a role in catabolism of amino acids to long-chain and
complex alcohols; required for expression of enzymes
involved in thiamine biosynthesis"
/codon_start=1
/product="branched-chain-2-oxoacid decarboxylase THI3"
/protein_id="NP_010203.1"
/db_xref="GI:6320123"
/db_xref="SGD:S000002238"
/db_xref="GeneID:851479"
/translation="MNSSYTQRYALPKCIAISDYLFHRLNQLNIHTIFGLSGEFSMPL
LDKLYNIPNLRWAGNSNELNAAYAADGYSRLKGLGCLITTFGVGELSAINGVAGSYAE
HVGILHIVGMPPTSAQTKQLLLHHTLGNGDFTVFHRIASDVACYTTLIIDSELCADEV
DKCIKKAWIEQRPVYMGMPVNQVNLPIESARLNTPLDLQLHKNDPDVEKEVISRILSF
IYKSQNPAIIVDACTSRQNLIEETKELCNRLKFPVFVTPMGKGTVNETDPQFGGVFTG
SISAPEVREVVDFADFIIVIGCMLSEFSTSTFHFQYKTKNCALLYSTSVKLKNATYPD
LSIKLLLQKILANLDESKLSYQPSEQPSMMVPRPYPAGNVLLRQEWVWNEISHWFQPG
DIIITETGASAFGVNQTRFPVNTLGISQALWGSVGYTMGACLGAEFAVQEINKDKFPA
TKHRVILFMGDGAFQLTVQELSTIVKWGLTPYIFVMNNQGYSVDRFLHHRSDASYYDI
QPWNYLGLLRVFGCTNYETKKIITVGEFRSMISDPNFATNDKIRMIEIMLPPRDVPQA
LLDRWVVEKEQSKQVQEENENSSAVNTPTPEFQPLLKKNQVGY"
gene complement(312951..314748)
/gene="MRK1"
/locus_tag="YDL079C"
/db_xref="GeneID:851480"
mRNA complement(join(312951..314044,314337..314748))
/gene="MRK1"
/locus_tag="YDL079C"
/product="Mrk1p"
/transcript_id="NM_001180138.1"
/db_xref="GI:296143288"
/db_xref="GeneID:851480"
CDS complement(join(312951..314044,314337..314748))
/gene="MRK1"
/locus_tag="YDL079C"
/EC_number="2.7.11.1"
/note="Glycogen synthase kinase 3 (GSK-3) homolog; one of
four GSK-3 homologs in S. cerevisiae that function to
activate Msn2p-dependent transcription of stress
responsive genes and that function in protein degradation"
/codon_start=1
/product="Mrk1p"
/protein_id="NP_010204.1"
/db_xref="GI:6320124"
/db_xref="SGD:S000002237"
/db_xref="GeneID:851480"
/translation="MTDVLRSLVRKISFNNSDNLQLKHKTSIQSNTALEKKKRKPDTI
KKVSDVQVHHTVPNFNNSSEYINDIENLIISKLIDGGKEGIAVDHIEHANISDSKTDG
KVANKHENISSKLSKEKVEKMINFDYRYIKTKERTIHKRVYKHDRKTDVDRKNHGGTI
DISYPTTEVVGHGSFGVVVTTVIIETNQKVAIKKVLQDRRYKNRELETMKMLCHPNTV
GLQYYFYEKDEEDEVYLNLVLDYMPQSLYQRLRHFVNLKMQMPRVEIKFYAYQLFKAL
NYLHNVPRICHRDIKPQNLLVDPTTFSFKICDFGSAKCLKPDQPNVSYICSRYYRAPE
LMFGATNYSNQVDVWSSACVIAELLLGKPLFSGESGIDQLVEIIKIMGIPTKDEISGM
NPNYEDHVFPNIKPITLAEIFKAEDPDTLDLLTKTLKYHPCERLVPLQCLLSSYFDET
KRCDTDTYVKAQNLRIFDFDVETELGHVPLVERPAIEERLKHFVSAPSSSL"
gene complement(315357..316388)
/gene="MDH3"
/locus_tag="YDL078C"
/db_xref="GeneID:851481"
mRNA complement(315357..316388)
/gene="MDH3"
/locus_tag="YDL078C"
/product="malate dehydrogenase MDH3"
/transcript_id="NM_001180137.1"
/db_xref="GI:296143289"
/db_xref="GeneID:851481"
CDS complement(315357..316388)
/gene="MDH3"
/locus_tag="YDL078C"
/EC_number="1.1.1.37"
/note="Peroxisomal malate dehydrogenase, catalyzes
interconversion of malate and oxaloacetate; involved in
the glyoxylate cycle"
/codon_start=1
/product="malate dehydrogenase MDH3"
/protein_id="NP_010205.1"
/db_xref="GI:6320125"
/db_xref="SGD:S000002236"
/db_xref="GeneID:851481"
/translation="MVKVAILGASGGVGQPLSLLLKLSPYVSELALYDIRAAEGIGKD
LSHINTNSSCVGYDKDSIENTLSNAQVVLIPAGVPRKPGLTRDDLFKMNAGIVKSLVT
AVGKFAPNARILVISNPVNSLVPIAVETLKKMGKFKPGNVMGVTNLDLVRAETFLVDY
LMLKNPKIGQEQDKTTMHRKVTVIGGHSGETIIPIITDKSLVFQLDKQYEHFIHRVQF
GGDEIVKAKQGAGSATLSMAFAGAKFAEEVLRSFHNEKPETESLSAFVYLPGLKNGKK
AQQLVGDNSIEYFSLPIVLRNGSVVSIDTSVLEKLSPREEQLVNTAVKELRKNIEKGK
SFILDSSKL"
rep_origin 316388..316971
/note="ARS412;
Putative replication origin, identified in multiple array
studies, not yet confirmed by plasmid-based assay"
/db_xref="SGD:S000130172"
gene complement(316971..320120)
/gene="VAM6"
/locus_tag="YDL077C"
/gene_synonym="CVT4; VPL18; VPL22; VPS39"
/db_xref="GeneID:851482"
mRNA complement(316971..320120)
/gene="VAM6"
/locus_tag="YDL077C"
/gene_synonym="CVT4; VPL18; VPL22; VPS39"
/product="Vam6p"
/transcript_id="NM_001180136.1"
/db_xref="GI:296143290"
/db_xref="GeneID:851482"
CDS complement(316971..320120)
/gene="VAM6"
/locus_tag="YDL077C"
/gene_synonym="CVT4; VPL18; VPL22; VPS39"
/note="Vacuolar protein that plays a critical role in the
tethering steps of vacuolar membrane fusion by
facilitating guanine nucleotide exchange on small
guanosine triphosphatase Ypt7p"
/codon_start=1
/product="Vam6p"
/protein_id="NP_010206.1"
/db_xref="GI:6320126"
/db_xref="SGD:S000002235"
/db_xref="GeneID:851482"
/translation="MLRAQKLHSLKSSDITAILPTEQSQKLVLAKKNGDVEVYSRDGN
TLKLFQVYPDLLQNAKNDPLPPVIENFYFANELSTIFAQCKETLILLSTTNLHEYDRI
IDRRGINHCWLFERSHKNKEEKNTYLIYSTINTAKMRVLIWEGRTYKNMMEASLSYRK
ETIRSIYPGETGITLATDLGIYHWPYNKPSLIRIEKTVKNKFPKDMISALTELKEQAE
KVIEKKPKKNSHFDAQSFSSMDRMSRKSSMSSLWYRTIRNERGNKIRYTFELDGNDAT
PMIIDGATKKIFKVELMHNNEEPFLIATDHATFSESNSEFDHMQYLSSNLLMLYNSST
IKFVDYENGFTFLQQKIPEGIKWVKNLSGTYFLVWTSNDEVQLFSYHVDDGSEDDDQE
SICGDINDPDFYQLWRKVLFYKFFIDSPHSKELCVSDNPEESLDICAMKLRDLTVMWC
LRIFDKFQNYMVQLERSRNSRMIRSKCEEMIIKSIFDLFIKFWAPPQLVILKVFPSAI
SSLVLEITGQEHHCLLKEAEEVKETYDIPPHLLNRWCLPYLTDTRRHLQNLLSKENDD
ESRITWCYRDREIKQSFDFFLISNHDDVDLNTMLTLIDTVLFKCYLYYNPPMVGPFIR
VENHCDSHVIVTELKIRHMFKDLIDFYYKRGNHEEALKFLTDLVDELENDNTDQKQRQ
KIDHGVKILVIYYLKKLSNPQLDVIFTYTDWLLNRHNDSIKEILSSIFFYDSQACSSR
DHLKVYGYIKKFDKLLAIQYLEFAISTFRLEGNKLHTVLIKLYLENLDIPSTRIKLKS
LLETTSVYEPRTILKLLNDAIESGSDQLPTNQLNFVKYLKIFPLSKLENHKEAVHILL
DEIDDYKAATSYCNDVYQSDSTKGEELLLYLYSKLVSIYDSNRNSKLILNFLQDHGSK
LNSAEIYKNLPQDISLYDIGRVVSQLLKKHTSKMDETRLEKALLQVELVATTYKLNER
MSSYGVLSDSHKCPICKKVISNFGTDSISWFTREGRNIITHYNCGKVLQERFNAKNEK
SSRIKQKTLGEVINELNNK"
gene complement(320668..321552)
/gene="RXT3"
/locus_tag="YDL076C"
/db_xref="GeneID:851483"
mRNA complement(320668..321552)
/gene="RXT3"
/locus_tag="YDL076C"
/product="Rxt3p"
/transcript_id="NM_001180135.1"
/db_xref="GI:296143291"
/db_xref="GeneID:851483"
CDS complement(320668..321552)
/gene="RXT3"
/locus_tag="YDL076C"
/note="Subunit of the RPD3L complex; involved in histone
deacetylation; protein abundance increases in response to
DNA replication stress"
/codon_start=1
/product="Rxt3p"
/protein_id="NP_010207.1"
/db_xref="GI:6320127"
/db_xref="SGD:S000002234"
/db_xref="GeneID:851483"
/translation="MSVSEQDPNRAYRETQSQIYKLQETLLNSARTKNKQEEGQESNT
HSFPEQYMHYQNGRNSAYDLPNVSSQSVLAFTEKHYPNKLKNLGTLYYNRFKEGSFDE
DSTSYSDRHSFPYNLYDNTLPPPFLPAIGIQNINNIATLKITYEDIQASFNNIESPRK
RNNEIWGCDIYSDDSDPILVLRHCGFKIGAPSGGSFHKLRRTPVNVTNQDNVTGNLPL
LEGTPFDLEVELLFLPTLQKYPSVKRFDITSREWGSEATVIHDGLSYGIYSIVIKQRL
DRDKPHEPNGYIKNLKWT"
gene 322226..322988
/gene="RPL31A"
/locus_tag="YDL075W"
/gene_synonym="RPL34"
/db_xref="GeneID:851484"
mRNA join(322226..322282,322704..322988)
/gene="RPL31A"
/locus_tag="YDL075W"
/gene_synonym="RPL34"
/product="ribosomal 60S subunit protein L31A"
/transcript_id="NM_001180134.1"
/db_xref="GI:296143292"
/db_xref="GeneID:851484"
CDS join(322226..322282,322704..322988)
/gene="RPL31A"
/locus_tag="YDL075W"
/gene_synonym="RPL34"
/note="Ribosomal 60S subunit protein L31A; associates with
karyopherin Sxm1p; loss of both Rpl31p and Rpl39p confers
lethality; homologous to mammalian ribosomal protein L31,
no bacterial homolog; RPL31A has a paralog, RPL31B, that
arose from the whole genome duplication"
/codon_start=1
/product="ribosomal 60S subunit protein L31A"
/protein_id="NP_010208.1"
/db_xref="GI:6320128"
/db_xref="SGD:S000002233"
/db_xref="GeneID:851484"
/translation="MAGLKDVVTREYTINLHKRLHGVSFKKRAPRAVKEIKKFAKLHM
GTDDVRLAPELNQAIWKRGVKGVEYRLRLRISRKRNEEEDAKNPLFSYVEPVLVASAK
GLQTVVVEEDA"
gene complement(323217..323471)
/locus_tag="snR63"
/db_xref="GeneID:9164876"
ncRNA complement(323217..323471)
/locus_tag="snR63"
/ncRNA_class="snoRNA"
/product="SNR63"
/note="C/D box small nucleolar RNA (snoRNA), guides
2'-O-methylation of large subunit (LSU) rRNA at position
A2256"
/db_xref="SGD:S000006454"
/db_xref="GeneID:9164876"
gene complement(324047..326149)
/gene="BRE1"
/locus_tag="YDL074C"
/db_xref="GeneID:851485"
mRNA complement(324047..326149)
/gene="BRE1"
/locus_tag="YDL074C"
/product="E3 ubiquitin-protein ligase BRE1"
/transcript_id="NM_001180133.1"
/db_xref="GI:296143293"
/db_xref="GeneID:851485"
CDS complement(324047..326149)
/gene="BRE1"
/locus_tag="YDL074C"
/EC_number="6.3.2.-"
/note="E3 ubiquitin ligase, forms heterodimer with Rad6p
to monoubiquinate histone H2B-K123, which is required for
the subsequent methylation of histone H3-K4 and H3-K79;
required for DSBR, transcription, silencing, and
checkpoint control"
/codon_start=1
/product="E3 ubiquitin-protein ligase BRE1"
/protein_id="NP_010209.1"
/db_xref="GI:6320129"
/db_xref="SGD:S000002232"
/db_xref="GeneID:851485"
/translation="MTAEPATKKIKLELSDPSEPLTQSDVIAFQKEALFRCINRRRVD
FEALRKQYELSRRECIDVSRKLANIMALIVTLARFIETFCTDANEKQLCREIAQGDET
LIVQRSDSFMKLLTKYGKPNTTDSNTNSNASDHIQELTTELKNLRKSKEELFYENSQL
TEEISALKEYYTNIIRKYDRDESFTIKRVFKEDKTDAVKELREDEKESNENNIKSGNK
DSSAINGDNTSKKSEKGDELVQAEDERKEDAENEKLELDLKFSDLRAEINSLSSTIKD
LENIRRENEEELIKTRSEVSNLKKQQIAAADQDPDFKSYDHESLLAKIQHLTEQNAEL
SEINSSFLSKFQVLAKEKEIYTKKVREEFQKSLDSLVEMNSSLEKDVVRIRTARDDLL
SKIAILEAEKSKTEVLSDLQHAIDILKEQWTKIDQRSNDTKSSSTQDALIKEIQDLEK
GFRELSDLTHKKYSEIINHESVISKLTVEKTKADQKYFAAMRSKDSILIEIKTLSKSL
SKSNELILQLKDSDRLLQQKIGNLHKQLDLSQNNERRLIDSSKTETLKIIDLNNTSTK
LKRSLEKLQEESNKSIADMTHLETKLNDTEIELKHFKQKASHLESKCEKLHDTLFRGN
NKNKGSSDEALVEELANFRTLVYCSLCSKNWKNMAIKTCGHVFCENCCKERLAARMRK
CPTCNKAFSSNDLLTVHL"
gene 326613..329567
/locus_tag="YDL073W"
/db_xref="GeneID:851486"
mRNA 326613..329567
/locus_tag="YDL073W"
/product="hypothetical protein"
/transcript_id="NM_001180132.1"
/db_xref="GI:296143294"
/db_xref="GeneID:851486"
CDS 326613..329567
/locus_tag="YDL073W"
/note="hypothetical protein; YDL073W is not an essential
gene"
/codon_start=1
/product="hypothetical protein"
/protein_id="NP_010210.1"
/db_xref="GI:6320130"
/db_xref="SGD:S000002231"
/db_xref="GeneID:851486"
/translation="MGPAIHNQLYECGLKTTSQDGFLMDNYETQLFQSLNRFINFINN
ANQSASNKEQNTKFCKSSSNFLRLKLLTVLRQWCDSSRSNCTLEVRDVLTQWWVTLLN
FLNSDTSLQIDTALELSLSIELTSVCLECLSKIMTILIILPFHSSRDMEIYSHHLLLT
IHCITNKLILISKNSKKLKRTNSDDKCSINDKKLQYLNKYSSLLRAFIGKLNAYAFFY
LPEDFHFDTILLLTVSPQISSSIQTSLFSWKKRQYKFTDDQGQMIRTEAFENKDTKFF
KIIVSYIKNDFVLMSFYWHYWYIILQFMKFSDSDVGIKKSTLSCIPGSEILLTHVTTR
FLNSDLNKFTRIIKQTPNPRIANENVTESHPNFKSLNSSNALITSERINDYVFSNFKT
IKLWECLRSLSGCILKENHPEYLENMLSLHESLLIDYVSTISAYDYIAANVIYNKVLQ
FIIFQFESLPSLKFIQWRSWYNGLLSMLRTKNVNCQTVSLLCLFNIWKHVTIEDRDEI
VKVLLSDFWESLIFENEFPLIRILFMKVLVFKIIPSVQNSSSLRFLPHDRIKQLYEEL
LVNKEELFEMQKHDSNDIVAHRKNALVFNGNSRLMMIPKKPNTEDHLVYKINHDKNLT
TERFPSVSSVANTRPNVILKNGKYAYDILDEMTSKAAFLLAEKKTRLNPKKNHKIMDG
YEGGQENEDNDEDSEDSGSHKNKRKEGNSSLSATLNTWLSKFSSTSEDSQKKKEQANE
LGNDFEYDEDVADFAEILPKQSSSNIEKIFKHGNNSGSMVSYNSSIKLNRRENILIGP
PELRFSNEIKEHNSIATIFKLVFIQTNRRVVEKIDLANMKWGTIHGGSKYMKPLPVPK
DLVASVAKNESETRNLATLCGNGLDFEIPVPDFNIFGKCMEDEQDVAKIGNQNVEDLK
VTGGREVTIWKQIQDMKLRTRIQKICVLIETFNATVREYFEFSNRLEHDGIFIDFEVR
KPSSNNSINIKV"
rep_origin 329566..329814
/note="ARS413;
Autonomously Replicating Sequence"
/db_xref="SGD:S000118432"
gene complement(329836..330447)
/gene="YET3"
/locus_tag="YDL072C"
/db_xref="GeneID:851487"
mRNA complement(329836..330447)
/gene="YET3"
/locus_tag="YDL072C"
/product="Yet3p"
/transcript_id="NM_001180131.1"
/db_xref="GI:296143295"
/db_xref="GeneID:851487"
CDS complement(329836..330447)
/gene="YET3"
/locus_tag="YDL072C"
/note="hypothetical protein; YET3 null mutant decreases
the level of secreted invertase; homolog of human BAP31
protein; protein abundance increases in response to DNA
replication stress"
/codon_start=1
/product="Yet3p"
/protein_id="NP_010211.1"
/db_xref="GI:6320131"
/db_xref="SGD:S000002230"
/db_xref="GeneID:851487"
/translation="MSLYYTLVFAILVVEIFMFSILALPIPSRYRRPLTLLLLKPFKS
STVQVAIKCVLGFILLLFIDCINRVYSIDKELQLSSASQNNGAIIAQDRIEVLSRKFF
AQRNMYLTGITLFLTFVVVRTFGLVIELLTMKDIYRASPPVASSDVKKNDSVTAEAAA
QSGASKDDHGDEKNFELLKKIQDIDDEIARLKEKSESLQEEIN"
gene 331024..332940
/gene="BDF2"
/locus_tag="YDL070W"
/db_xref="GeneID:851488"
mRNA 331024..332940
/gene="BDF2"
/locus_tag="YDL070W"
/product="Bdf2p"
/transcript_id="NM_001180129.1"
/db_xref="GI:296143296"
/db_xref="GeneID:851488"
CDS 331024..332940
/gene="BDF2"
/locus_tag="YDL070W"
/note="Protein involved in transcription initiation; acts
at TATA-containing promoters; associates with the basal
transcription factor TFIID; contains two bromodomains;
corresponds to the C-terminal region of mammalian TAF1;
redundant with Bdf1p; protein abundance increases in
response to DNA replication stress"
/codon_start=1
/product="Bdf2p"
/protein_id="NP_010213.1"
/db_xref="GI:6320132"
/db_xref="SGD:S000002228"
/db_xref="GeneID:851488"
/translation="MSRTNMDTRHAHSALLAAPQSATANSRSSNSSSESSSNKNNINV
GVGDDSGNVSAVSIDDGPHFRDIFHYGHEENYKLASSGITNLNSSSHAHQTLSPISIS
NASTPESFPEHPLGLERETEPALEAEMEAEELPPHQSKYLLSSIKATKRLKDARPFLK
PVDPIALNIPHYFNYVQTPMDLSLIETKLQGNVYHSVEQVTSDFKTMVDNCLNFNGPE
SSISSMAKRIQKYFEKKLSAMPPRVLPASALKKTSRNRKKNEDMDSPLVIRRSVSTTN
DNIGESGNREGVSGGRPKRTIHPPKSKDLFDIYENSKPKSKTLQKKFRTCLKILKVLM
SKKNSDINFPFLQPVDPIALNLPNYFDVVKNPMDLGTISNNLMNWKYKTIDQFVDDLN
LVFYNCFQFNPEGNEVHSMGKKLKELFNFHWLENQDILNEIETDSDLEEDNYSSSYSS
DDEYDDEDINENDITNPAIQYLEQKLKKMEVELQQLKRQELSKLSKERKRKHLGKTLL
RRKAMKHSVDDLKKSITDKINELSDLEMNGMIRIIKNSLPADEILTSNEDEIEIDLDI
LDEATIARIYERYFEKKNNNNSKRKLSGNYSTAPTNKKKKTLKFLEKDEIINNNNYSD
SEEDSSDSSDSDSD"
gene complement(333121..333810)
/gene="CBS1"
/locus_tag="YDL069C"
/db_xref="GeneID:851491"
mRNA complement(333121..333810)
/gene="CBS1"
/locus_tag="YDL069C"
/product="Cbs1p"
/transcript_id="NM_001180128.1"
/db_xref="GI:296143297"
/db_xref="GeneID:851491"
CDS complement(333121..333810)
/gene="CBS1"
/locus_tag="YDL069C"
/note="Mitochondrial translational activator of the COB
mRNA; membrane protein that interacts with translating
ribosomes, acts on the COB mRNA 5'-untranslated leader"
/codon_start=1
/product="Cbs1p"
/protein_id="NP_010214.2"
/db_xref="GI:37362630"
/db_xref="SGD:S000002227"
/db_xref="GeneID:851491"
/translation="MLRTKVFATTVARISGIRRYIPIRTINTVTKKNISKIEKLCEVL
EVNPDGYKGKERIPTKELTKLLYTTSRNMLVRVPMTGDLSTGNTFETRNETLQKLGEQ
LIHLEINKMLTITFTNFNQFNIMNKNFNYIHNLDRARVVNMDSISWLIKNSLKINQLA
HLRIPANLPKEMGLTSSSNDFQNLNDWKVILSFIGYLKLLEIKNDNKKFIESIIKTIC
IPLINYHLRKS"
gene complement(334217..334396)
/gene="COX9"
/locus_tag="YDL067C"
/db_xref="GeneID:851492"
mRNA complement(334217..334396)
/gene="COX9"
/locus_tag="YDL067C"
/product="cytochrome c oxidase subunit VIIa"
/transcript_id="NM_001180126.1"
/db_xref="GI:296143298"
/db_xref="GeneID:851492"
CDS complement(334217..334396)
/gene="COX9"
/locus_tag="YDL067C"
/EC_number="1.9.3.1"
/note="Subunit VIIa of cytochrome c oxidase, which is the
terminal member of the mitochondrial inner membrane
electron transport chain"
/codon_start=1
/product="cytochrome c oxidase subunit VIIa"
/protein_id="NP_010216.1"
/db_xref="GI:6320136"
/db_xref="SGD:S000002225"
/db_xref="GeneID:851492"
/translation="MTIAPITGTIKRRVIMDIVLGFSLGGVMASYWWWGFHMDKINKR
EKFYAELAERKKQEN"
gene 334835..336121
/gene="IDP1"
/locus_tag="YDL066W"
/db_xref="GeneID:851493"
mRNA 334835..336121
/gene="IDP1"
/locus_tag="YDL066W"
/product="isocitrate dehydrogenase (NADP(+)) IDP1"
/transcript_id="NM_001180125.1"
/db_xref="GI:296143299"
/db_xref="GeneID:851493"
CDS 334835..336121
/gene="IDP1"
/locus_tag="YDL066W"
/EC_number="1.1.1.42"
/note="Mitochondrial NADP-specific isocitrate
dehydrogenase, catalyzes the oxidation of isocitrate to
alpha-ketoglutarate; not required for mitochondrial
respiration and may function to divert alpha-ketoglutarate
to biosynthetic processes"
/codon_start=1
/product="isocitrate dehydrogenase (NADP(+)) IDP1"
/protein_id="NP_010217.1"
/db_xref="GI:6320137"
/db_xref="SGD:S000002224"
/db_xref="GeneID:851493"
/translation="MSMLSRRLFSTSRLAAFSKIKVKQPVVELDGDEMTRIIWDKIKK
KLILPYLDVDLKYYDLSVESRDATSDKITQDAAEAIKKYGVGIKCATITPDEARVKEF
NLHKMWKSPNGTIRNILGGTVFREPIVIPRIPRLVPRWEKPIIIGRHAHGDQYKATDT
LIPGPGSLELVYKPSDPTTAQPQTLKVYDYKGSGVAMAMYNTDESIEGFAHSSFKLAI
DKKLNLFLSTKNTILKKYDGRFKDIFQEVYEAQYKSKFEQLGIHYEHRLIDDMVAQMI
KSKGGFIMALKNYDGDVQSDIVAQGFGSLGLMTSILVTPDGKTFESEAAHGTVTRHYR
KYQKGEETSTNSIASIFAWSRGLLKRGELDNTPALCKFANILESATLNTVQQDGIMTK
DLALACGNNERSAYVTTEEFLDAVEKRLQKEIKSIE"
gene complement(336249..337277)
/gene="PEX19"
/locus_tag="YDL065C"
/gene_synonym="PAS12"
/db_xref="GeneID:851494"
mRNA complement(336249..337277)
/gene="PEX19"
/locus_tag="YDL065C"
/gene_synonym="PAS12"
/product="Pex19p"
/transcript_id="NM_001180124.1"
/db_xref="GI:296143300"
/db_xref="GeneID:851494"
CDS complement(336249..337277)
/gene="PEX19"
/locus_tag="YDL065C"
/gene_synonym="PAS12"
/note="Chaperone and import receptor for newly-synthesized
class I PMPs; binds peroxisomal membrane proteins (PMPs)
in the cytoplasm and delivers them to the peroxisome for
subsequent insertion into the peroxisomal membrane;
interacts with Myo2p and contributes to peroxisome
partitioning"
/codon_start=1
/product="Pex19p"
/protein_id="NP_010218.2"
/db_xref="GI:93117371"
/db_xref="SGD:S000002223"
/db_xref="GeneID:851494"
/translation="MNENEYDNFDDLDDLLDEDPTKLDEAEPDDVQAKGSVYNDSENK
EKNAESKDSDGVQVANESEEDPELKEMMVDLQNEFANLMKNNGNENNVKTEDFNKLIS
ALEEAAKVPHQQMEQGCSSLKSNSTDKGTVNGSNPGFKNIVSNTLDRLKENGNKVDTS
LAEETKESQRSGQNNNIDDILSQLLDQMVASGGKESAENQFDLKDGEMDDAITKILDQ
MTSKEVLYEPMKEMRSEFGVWFQENGENEEHKEKIGTYKRQFNIVDEIVNIYELKDYD
ELKHKDRVTELLDELEQLGDSPIRSANSPLKHGNEEEELMKMLEIDGNDPNLGNLDKE
LTDGCKQQ"
gene 337487..338070
/gene="UBC9"
/locus_tag="YDL064W"
/db_xref="GeneID:851495"
mRNA join(337487..337524,337635..338070)
/gene="UBC9"
/locus_tag="YDL064W"
/product="E2 SUMO-conjugating protein UBC9"
/transcript_id="NM_001180123.1"
/db_xref="GI:296143301"
/db_xref="GeneID:851495"
CDS join(337487..337524,337635..338070)
/gene="UBC9"
/locus_tag="YDL064W"
/EC_number="6.3.2.-"
/note="SUMO-conjugating enzyme involved in the Smt3p
conjugation pathway; nuclear protein required for S- and
M-phase cyclin degradation and mitotic control; involved
in proteolysis mediated by the anaphase-promoting complex
cyclosome (APCC)"
/codon_start=1
/product="E2 SUMO-conjugating protein UBC9"
/protein_id="NP_010219.1"
/db_xref="GI:6320139"
/db_xref="SGD:S000002222"
/db_xref="GeneID:851495"
/translation="MSSLCLQRLQEERKKWRKDHPFGFYAKPVKKADGSMDLQKWEAG
IPGKEGTNWAGGVYPITVEYPNEYPSKPPKVKFPAGFYHPNVYPSGTICLSILNEDQD
WRPAITLKQIVLGVQDLLDSPNPNSPAQEPAWRSFSRNKAEYDKKVLLQAKQYSK"
gene complement(338272..340134)
/gene="SYO1"
/locus_tag="YDL063C"
/db_xref="GeneID:851497"
mRNA complement(338272..340134)
/gene="SYO1"
/locus_tag="YDL063C"
/product="Syo1p"
/transcript_id="NM_001180122.1"
/db_xref="GI:296143302"
/db_xref="GeneID:851497"
CDS complement(338272..340134)
/gene="SYO1"
/locus_tag="YDL063C"
/note="Transport adaptor or symportin; facilitates
synchronized nuclear coimport of the two 5S-rRNA binding
proteins Rpl5p and Rpl11p; required for biogenesis of the
large ribosomal subunit; green fluorescent protein
(GFP)-fusion protein localizes to the cytoplasm and
nucleus"
/codon_start=1
/product="Syo1p"
/protein_id="NP_010220.1"
/db_xref="GI:6320141"
/db_xref="SGD:S000002221"
/db_xref="GeneID:851497"
/translation="MGRSKKRSRASSSRLNPLRKAGSNDNNKDTNVVNKKLQPLLQNL
SSVVPNDRSIALSSISVLCEDAHMRQLLLKEKLVPIILNKLLNDSNSDIVVESFGLLR
NLSLEEGYDVSIYLWRSDIWTSITSNFGRIVESLSALQAAEQQPQLKPAGKSKIESKR
LLFDFADNLLSLVVALSNGSDDILNEILTESKINEIFQVISQLLKYGVEKLPINLFNT
TLDLIYDLSSESFEFIDHVSNNELLSQFLNGLSPALHPQANELTKVLIEGIHCQFLDM
KITYDQCNKMIHSVCHSINNIDPVQLVNDINNPVEIGPATSKDESSKVITKIKDYNAK
RNESMIKLQSIEIAIDLITAIIEIVASKYESPESQEVAIPEELINTLTNFLPHVFMIL
KDTFTSRILIGWNNLIWLFVSLSLTELSGELLTTLWSYVTQLDSQDDLSIKIGRMGCI
WALLKLIFPDGAFESENRALINVQMLNNSGFARGIIEEFQNNNDLELQQKCINVLSTY
AMIQGQIDANKEIGQFFIQTLTQLNVRPEILIEMTNSLFQIYGDASYDYNEPIFVRGG
FLSILKDQVVPNLRQQFKMVDKNKNPELKERCHDCFTTLDSFIHYKMNENSTNQ"
gene complement(340628..340798)
/gene="RPS29B"
/locus_tag="YDL061C"
/db_xref="GeneID:851498"
mRNA complement(340628..340798)
/gene="RPS29B"
/locus_tag="YDL061C"
/product="ribosomal 40S subunit protein S29B"
/transcript_id="NM_001180120.1"
/db_xref="GI:296143303"
/db_xref="GeneID:851498"
CDS complement(340628..340798)
/gene="RPS29B"
/locus_tag="YDL061C"
/note="Protein component of the small (40S) ribosomal
subunit; homologous to mammalian ribosomal protein S29 and
bacterial S14; RPS29B has a paralog, RPS29A, that arose
from the whole genome duplication"
/codon_start=1
/product="ribosomal 40S subunit protein S29B"
/protein_id="NP_010222.1"
/db_xref="GI:6320142"
/db_xref="SGD:S000002219"
/db_xref="GeneID:851498"
/translation="MAHENVWFSHPRRFGKGSRQCRVCSSHTGLVRKYDLNICRQCFR
EKANDIGFHKYR"
gene 341619..343985
/gene="TSR1"
/locus_tag="YDL060W"
/db_xref="GeneID:851499"
mRNA 341619..343985
/gene="TSR1"
/locus_tag="YDL060W"
/product="Tsr1p"
/transcript_id="NM_001180119.1"
/db_xref="GI:296143304"
/db_xref="GeneID:851499"
CDS 341619..343985
/gene="TSR1"
/locus_tag="YDL060W"
/note="Protein required for processing of 20S pre-rRNA in
the cytoplasm; associates with pre-40S ribosomal
particles; inhibits the premature association of 60S
subunits with assembling 40S subunits in the cytoplasm;
similar to Bms1p; relocalizes from nucleus to cytoplasm
upon DNA replication stress"
/codon_start=1
/product="Tsr1p"
/protein_id="NP_010223.1"
/db_xref="GI:6320143"
/db_xref="SGD:S000002218"
/db_xref="GeneID:851499"
/translation="MAGHSHRSSLKNGHKSYKSKHASKGALKRLYKGKVEKEPVGTGK
PDKQVSKLQRKNKAKQLRAQRILDSIENRKLFEGKNGAAKIITIVPLVNDLDPLDILY
KLLKCADDEGIMVQEVDSKRIFNVHIKKFKSNLKIIIPDMTNFLNILDCAKVADFVVF
GLSGVQEVDEEFGEQIIRALELQGIASYIGVISNLSAVHEKEKFQLDVKQSLESYFKH
FFPSEERVYNLEKNSDALNVLRTLCQRLPRSINWRDNRGYVVADFVDFVETSPDSGDL
VIEGTVRGIGFNANRLVHIPDFGDFQLNKIEKISESSQKRKIIKEKATDSLSLELDLQ
TVFESNMNRDTLDEYAPEGTEDWSDYDEDFEYDGLTTARYDDHGFLPGREQTSKKAAV
PKGTSDYQAKWYLDDVIDANEEEEAEQTNGKDETMMEIDDEMMVEQDNEEVAGDEEYD
IEDNEGFEELSPEEEERQLREFRDMEKEDREFPDEIELEPSESAIERLKRYRGLKNLY
NCDWQVDEKDPSSPAEWKRLLRIGNYKNTKNRIIKETKNEAQAIAGDRIRMFIRFPKF
LLEKIQDPKQLLFAVYGLLLHEHKNAVVNFSLQRWEQYDKPVPSQEPIVVQYGVRRYT
IQPLFSQGSNSPNNVHKYERFLHPDTVSVATCIAPVDFTQSPAIFFKPSPTDAKNIEL
IGHGTFLNADHSRILAKRAILTGHPFRFHKTVVTVRYMFFRPEDVEWFKSIPLFTKSG
RSGFIKESLGTHGYFKATFDGKLSAQDVVAMSLYKRMWPMPSLPWNGM"
gene complement(344237..344953)
/gene="RAD59"
/locus_tag="YDL059C"
/db_xref="GeneID:851500"
mRNA complement(344237..344953)
/gene="RAD59"
/locus_tag="YDL059C"
/product="Rad59p"
/transcript_id="NM_001180118.1"
/db_xref="GI:296143305"
/db_xref="GeneID:851500"
CDS complement(344237..344953)
/gene="RAD59"
/locus_tag="YDL059C"
/note="Protein involved DNA double-strand break repair;
repairs breaks in DNA during vegetative growth via
recombination and single-strand annealing; anneals
complementary single-stranded DNA; homologous to Rad52p;
forms nuclear foci upon DNA replication stress"
/codon_start=1
/product="Rad59p"
/protein_id="NP_010224.1"
/db_xref="GI:6320144"
/db_xref="SGD:S000002217"
/db_xref="GeneID:851500"
/translation="MTIQAKPSSSISYDSTTYGTAPGLDIKEFQIIEDWNGRPASAWS
VQRIGLLQSKIERYTYNIYHNNKYGKHNLSKLIPGHALIQFANETFGYDGWRMDVIDV
EARECQPFTAVNNGENTNTSEVKYTVVAEAQVKVTLKDGTNTQCGGLGRITLSSRGEC
YNRSKKEAVGDALKKALLSFEKIILDYETKITNNYYVDGLYGSKKIKNEANTNYNLLS
ATNSKPTFIKLEDAKGTHIK"
gene 345665..351037
/gene="USO1"
/locus_tag="YDL058W"
/gene_synonym="INT1"
/db_xref="GeneID:851501"
mRNA 345665..351037
/gene="USO1"
/locus_tag="YDL058W"
/gene_synonym="INT1"
/product="Uso1p"
/transcript_id="NM_001180117.1"
/db_xref="GI:296143306"
/db_xref="GeneID:851501"
CDS 345665..351037
/gene="USO1"
/locus_tag="YDL058W"
/gene_synonym="INT1"
/note="Essential protein involved in the vesicle-mediated
ER to Golgi transport step of secretion; binds membranes
and functions during vesicle docking to the Golgi;
required for assembly of the ER-to-Golgi SNARE complex"
/codon_start=1
/product="Uso1p"
/protein_id="NP_010225.1"
/db_xref="GI:6320145"
/db_xref="SGD:S000002216"
/db_xref="GeneID:851501"
/translation="MDIIQGLIQQPKIQSVDETIPTLCDRVENSTLISDRRSAVLGLK
AFSRQYRESVIASGLKPLLNTLKRDYMDEDSVKAILETILILFIRGDGHDDLTRGWIS
QQSRLQNGKYPSPLVMKQEKEQVDQFSLWIADALTQSEDLIHLLVEFWEIDNFHIRLY
TIQLLEAVMATRPLKARSALISLPTSISTMVSLLDDMHEPIRDEAILLLMAVVNDSPH
VQKLVAFENIFERLFSIIEEEGGLRGSLVVNDCLSLINNILKYNTSNQTLFLETGNLP
KLAHLLSEPISQDEVFFWNDQRIVNINTALDIVSLTVEPGNTVTTKHQNALLDSSVLM
VVLRLAFFHNIPKKVRPVALLTAANMVRSNEHAQLEFSKIDVPYFDPSLPVNSTANGG
PIKLIPVVSILINWMLYANSVHTFDTRVACSRLLKAYFMDNFDLQRDFLLKQVQLCNN
STNNVGDNAKENGGSNKSDKESDSDKDTDGKDGTEYEGSFKANLFEVLLNYDAELNLN
PFKLFFTTDIFMFFFQQDHKYSEELREITRNVTTGNDLEDEEPLKAIQTISELLTTSL
TAADIRIPISYLTFLIYWLFGDFKATNDFLSDKSVIKSLLSFSYQIQDEDVTIKCLVT
MLLGVAYEFSSKESPFPRKEYFEFITKTLGKDNYASRIKQFKKDSYFSKVDMNEDSIL
TPELDETGLPKVYFSTYFIQLFNENIYRIRTALSHDPDEEPINKISFEEVEKLQRQCT
KLKGEITSLQTETESTHENLTEKLIALTNEHKELDEKYQILNSSHSSLKENFSILETE
LKNVRDSLDEMTQLRDVLETKDKENQTALLEYKSTIHKQEDSIKTLEKGLETILSQKK
KAEDGINKMGKDLFALSREMQAVEENCKNLQKEKDKSNVNHQKETKSLKEDIAAKITE
IKAINENLEEMKIQCNNLSKEKEHISKELVEYKSRFQSHDNLVAKLTEKLKSLANNYK
DMQAENESLIKAVEESKNESSIQLSNLQNKIDSMSQEKENFQIERGSIEKNIEQLKKT
ISDLEQTKEEIISKSDSSKDEYESQISLLKEKLETATTANDENVNKISELTKTREELE
AELAAYKNLKNELETKLETSEKALKEVKENEEHLKEEKIQLEKEATETKQQLNSLRAN
LESLEKEHEDLAAQLKKYEEQIANKERQYNEEISQLNDEITSTQQENESIKKKNDELE
GEVKAMKSTSEEQSNLKKSEIDALNLQIKELKKKNETNEASLLESIKSVESETVKIKE
LQDECNFKEKEVSELEDKLKASEDKNSKYLELQKESEKIKEELDAKTTELKIQLEKIT
NLSKAKEKSESELSRLKKTSSEERKNAEEQLEKLKNEIQIKNQAFEKERKLLNEGSST
ITQEYSEKINTLEDELIRLQNENELKAKEIDNTRSELEKVSLSNDELLEEKQNTIKSL
QDEILSYKDKITRNDEKLLSIERDNKRDLESLKEQLRAAQESKAKVEEGLKKLEEESS
KEKAELEKSKEMMKKLESTIESNETELKSSMETIRKSDEKLEQSKKSAEEDIKNLQHE
KSDLISRINESEKDIEELKSKLRIEAKSGSELETVKQELNNAQEKIRINAEENTVLKS
KLEDIERELKDKQAEIKSNQEEKELLTSRLKELEQELDSTQQKAQKSEEERRAEVRKF
QVEKSQLDEKAMLLETKYNDLVNKEQAWKRDEDTVKKTTDSQRQEIEKLAKELDNLKA
ENSKLKEANEDRSEIDDLMLLVTDLDEKNAKYRSKLKDLGVEISSDEEDDEEDDEEDE
EEGQVA"
gene 351434..352420
/locus_tag="YDL057W"
/db_xref="GeneID:851502"
mRNA 351434..352420
/locus_tag="YDL057W"
/product="hypothetical protein"
/transcript_id="NM_001180116.1"
/db_xref="GI:296143307"
/db_xref="GeneID:851502"
CDS 351434..352420
/locus_tag="YDL057W"
/note="hypothetical protein; YDL057W is not an essential
gene"
/codon_start=1
/product="hypothetical protein"
/protein_id="NP_010226.1"
/db_xref="GI:6320146"
/db_xref="SGD:S000002215"
/db_xref="GeneID:851502"
/translation="MEKKHVTVQIQSAPPSYIKLEANEKFVYITSTMNGLSYQIAAIV
SYPEKRNSSTANKEDGKLLCKENKLALLLHGSQSHKNAIYQTLLAKRLAEFGYWVLRI
DFRGQGDSSDNCDPGLGRTLAQDLEDLSTVYQTVSDRSLRVQLYKTSTISLDVVVAHS
RGSLAMFKFCLKLHAAESPLPSHLINCAGRYDGRGLIERCTRLHPHWQAEGGFWANGP
RNGEYKDFWIPLSETYSIAGVCVPEFATIPQTCSVMSCYGMCDHIVPISAASNYARLF
EGRHSLKLIENADHNYYGIEGDPNALGLPIRRGRVNYSPLVVDLIMEYLQDT"
gene 352877..355378
/gene="MBP1"
/locus_tag="YDL056W"
/db_xref="GeneID:851503"
mRNA 352877..355378
/gene="MBP1"
/locus_tag="YDL056W"
/product="Mbp1p"
/transcript_id="NM_001180115.1"
/db_xref="GI:296143308"
/db_xref="GeneID:851503"
CDS 352877..355378
/gene="MBP1"
/locus_tag="YDL056W"
/note="Transcription factor involved in regulation of cell
cycle progression from G1 to S phase, forms a complex with
Swi6p that binds to MluI cell cycle box regulatory element
in promoters of DNA synthesis genes"
/codon_start=1
/product="Mbp1p"
/protein_id="NP_010227.1"
/db_xref="GI:6320147"
/db_xref="SGD:S000002214"
/db_xref="GeneID:851503"
/translation="MSNQIYSARYSGVDVYEFIHSTGSIMKRKKDDWVNATHILKAAN
FAKAKRTRILEKEVLKETHEKVQGGFGKYQGTWVPLNIAKQLAEKFSVYDQLKPLFDF
TQTDGSASPPPAPKHHHASKVDRKKAIRSASTSAIMETKRNNKKAEENQFQSSKILGN
PTAAPRKRGRPVGSTRGSRRKLGVNLQRSQSDMGFPRPAIPNSSISTTQLPSIRSTMG
PQSPTLGILEEERHDSRQQQPQQNNSAQFKEIDLEDGLSSDVEPSQQLQQVFNQNTGF
VPQQQSSLIQTQQTESMATSVSSSPSLPTSPGDFADSNPFEERFPGGGTSPIISMIPR
YPVTSRPQTSDINDKVNKYLSKLVDYFISNEMKSNKSLPQVLLHPPPHSAPYIDAPID
PELHTAFHWACSMGNLPIAEALYEAGTSIRSTNSQGQTPLMRSSLFHNSYTRRTFPRI
FQLLHETVFDIDSQSQTVIHHIVKRKSTTPSAVYYLDVVLSKIKDFSPQYRIELLLNT
QDKNGDTALHIASKNGDVVFFNTLVKMGALTTISNKEGLTANEIMNQQYEQMMIQNGT
NQHVNSSNTDLNIHVNTNNIETKNDVNSMVIMSPVSPSDYITYPSQIATNISRNIPNV
VNSMKQMASIYNDLHEQHDNEIKSLQKTLKSISKTKIQVSLKTLEVLKESSKDENGEA
QTNDDFEILSRLQEQNTKKLRKRLIRYKRLIKQKLEYRQTVLLNKLIEDETQATTNNT
VEKDNNTLERLELAQELTMLQLQRKNKLSSLVKKFEDNAKIHKYRRIIREGTEMNIEE
VDSSLDVILQTLIANNNKNKGAEQIITISNANSHA"
gene complement(355674..356759)
/gene="PSA1"
/locus_tag="YDL055C"
/gene_synonym="MPG1; SRB1; VIG9"
/db_xref="GeneID:851504"
mRNA complement(355674..356759)
/gene="PSA1"
/locus_tag="YDL055C"
/gene_synonym="MPG1; SRB1; VIG9"
/product="mannose-1-phosphate guanylyltransferase"
/transcript_id="NM_001180114.1"
/db_xref="GI:296143309"
/db_xref="GeneID:851504"
CDS complement(355674..356759)
/gene="PSA1"
/locus_tag="YDL055C"
/gene_synonym="MPG1; SRB1; VIG9"
/EC_number="2.7.7.13"
/note="GDP-mannose pyrophosphorylase (mannose-1-phosphate
guanyltransferase), synthesizes GDP-mannose from GTP and
mannose-1-phosphate in cell wall biosynthesis; required
for normal cell wall structure"
/codon_start=1
/product="mannose-1-phosphate guanylyltransferase"
/protein_id="NP_010228.1"
/db_xref="GI:6320148"
/db_xref="SGD:S000002213"
/db_xref="GeneID:851504"
/translation="MKGLILVGGYGTRLRPLTLTVPKPLVEFGNRPMILHQIEALANA
GVTDIVLAVNYRPEVMVETLKKYEKEYGVNITFSVETEPLGTAGPLKLAEDVLKKDNS
PFFVLNSDVICEYPFKELADFHKAHGGKGTIVATKVDEPSKYGVIVHDIATPNLIDRF
VEKPKEFVGNRINAGLYILNPEVIDLIEMKPTSIEKETFPILVEEKQLYSFDLEGFWM
DVGQPKDFLSGTVLYLNSLAKRQPKKLATGANIVGNALIDPTAKISSTAKIGPDVVIG
PNVTIGDGVRITRSVVLCNSTIKNHSLVKSTIVGWNSTVGQWCRLEGVTVLGDDVEVK
DEIYINGGKVLPHKSISDNVPKEAIIM"
gene 359577..359672
/locus_tag="tK(UUU)D"
/db_xref="GeneID:851505"
tRNA join(359577..359613,359637..359672)
/locus_tag="tK(UUU)D"
/product="tRNA-Lys"
/note="Lysine tRNA (tRNA-Lys), predicted by tRNAscan-SE
analysis; thiolation of uridine at wobble position (34)
requires Ncs6p"
/db_xref="SGD:S000006629"
/db_xref="GeneID:851505"
gene complement(359825..361285)
/gene="MCH1"
/locus_tag="YDL054C"
/db_xref="GeneID:851506"
mRNA complement(359825..361285)
/gene="MCH1"
/locus_tag="YDL054C"
/product="Mch1p"
/transcript_id="NM_001180113.1"
/db_xref="GI:296143310"
/db_xref="GeneID:851506"
CDS complement(359825..361285)
/gene="MCH1"
/locus_tag="YDL054C"
/note="Protein with similarity to mammalian
monocarboxylate permeases, which are involved in transport
of monocarboxylic acids across the plasma membrane; mutant
is not deficient in monocarboxylate transport"
/codon_start=1
/product="Mch1p"
/protein_id="NP_010229.1"
/db_xref="GI:6320149"
/db_xref="SGD:S000002212"
/db_xref="GeneID:851506"
/translation="MPLSKVEHYLSYHTRLLLPHVLSLQSSHRVAYIFSLLSAVSTGF
ITLISLYSQPWQKHLNYSSWQINTIASMTNLGMYLTPPILGMIADSHGPITLSLLAII
GFIPSYSYLAYVFNHPELSLGGNGDSSFNLSIICFVFIGISTSALYFSALLTCTKLYP
HTKLLSISLPTTCYGISSVVGSQLLRIKWFWSSNASSSSSNSDLNLGRVFQTFALVYV
VIGLLAWIATSVVSLLHFNEEQDNQKRLDDQTDVEQSPLLERSNHVQEKFTQTMLRIF
SDPVTYILAVSILLSLGPLEMFIANMGSLTNLLVQLDAPTLSTKLLSTYALSSTFTRL
LTGIVADFFAKKKISIKWILLTFLSLGVCAQLFLLKMTSSASPWGLVPTGSLVGIVYG
GLFTVYPTLVLLVWGERSFGTVYGSLLIAPAIGSMIFCMLYAKFYDSRCMSGGGDLRN
PSCISAVYKYSSIAFVVSAVLSAVVFWKLKSRKLRI"
gene complement(361699..362256)
/gene="PBP4"
/locus_tag="YDL053C"
/db_xref="GeneID:851507"
mRNA complement(361699..362256)
/gene="PBP4"
/locus_tag="YDL053C"
/product="Pbp4p"
/transcript_id="NM_001180112.1"
/db_xref="GI:296143311"
/db_xref="GeneID:851507"
CDS complement(361699..362256)
/gene="PBP4"
/locus_tag="YDL053C"
/note="Pbp1p binding protein; interacts strongly with
Pab1p-binding protein 1 (Pbp1p) in the yeast two-hybrid
system; also interacts with Lsm12p in a copurification
assay; relative distribution to the nucleus increases upon
DNA replication stress"
/codon_start=1
/product="Pbp4p"
/protein_id="NP_010230.1"
/db_xref="GI:6320150"
/db_xref="SGD:S000002211"
/db_xref="GeneID:851507"
/translation="MTTTSTTSVDGRTSSTLKATLSASGPNSNGPTPAVLPQKPKLTG
WAQAAAKALPRQQQQQQQARKDDSVAVQPANTKTKTIASTAPPANIKGSSTANGSSTN
KKFKRANKQPYNREEVRSYMHKLFQSYTAGEKSHSMKTYKQVLSETASGRVSTATDWG
TVSSSKNKNKKYGCLSDIAKVLRNQ"
gene complement(362672..363583)
/gene="SLC1"
/locus_tag="YDL052C"
/db_xref="GeneID:851508"
mRNA complement(362672..363583)
/gene="SLC1"
/locus_tag="YDL052C"
/product="1-acylglycerol-3-phosphate O-acyltransferase
SLC1"
/transcript_id="NM_001180111.1"
/db_xref="GI:296143312"
/db_xref="GeneID:851508"
CDS complement(362672..363583)
/gene="SLC1"
/locus_tag="YDL052C"
/EC_number="2.3.1.51"
/note="1-acyl-sn-glycerol-3-phosphate acyltransferase,
catalyzes the acylation of lysophosphatidic acid to form
phosphatidic acid, a key intermediate in lipid metabolism;
enzymatic activity detected in lipid particles and
microsomes"
/codon_start=1
/product="1-acylglycerol-3-phosphate O-acyltransferase
SLC1"
/protein_id="NP_010231.1"
/db_xref="GI:6320151"
/db_xref="SGD:S000002210"
/db_xref="GeneID:851508"
/translation="MSVIGRFLYYLRSVLVVLALAGCGFYGVIASILCTLIGKQHLAQ
WITARCFYHVMKLMLGLDVKVVGEENLAKKPYIMIANHQSTLDIFMLGRIFPPGCTVT
AKKSLKYVPFLGWFMALSGTYFLDRSKRQEAIDTLNKGLENVKKNKRALWVFPEGTRS
YTSELTMLPFKKGAFHLAQQGKIPIVPVVVSNTSTLVSPKYGVFNRGCMIVRILKPIS
TENLTKDKIGEFAEKVRDQMVDTLKEIGYSPAINDTTLPPQAIEYAALQHDKKVNKKI
KNEPVPSVSISNDVNTHNEGSSVKKMH"
gene 363952..364779
/gene="LHP1"
/locus_tag="YDL051W"
/gene_synonym="LAH1; YLA1"
/db_xref="GeneID:851509"
mRNA 363952..364779
/gene="LHP1"
/locus_tag="YDL051W"
/gene_synonym="LAH1; YLA1"
/product="Lhp1p"
/transcript_id="NM_001180110.1"
/db_xref="GI:296143313"
/db_xref="GeneID:851509"
CDS 363952..364779
/gene="LHP1"
/locus_tag="YDL051W"
/gene_synonym="LAH1; YLA1"
/note="RNA binding protein required for maturation of tRNA
and U6 snRNA precursors; acts as a molecular chaperone for
RNAs transcribed by polymerase III; homologous to human La
(SS-B) autoantigen"
/codon_start=1
/product="Lhp1p"
/protein_id="NP_010232.1"
/db_xref="GI:6320152"
/db_xref="SGD:S000002209"
/db_xref="GeneID:851509"
/translation="MSEKPQQEEQEKPQSRRNSFAVIEFTPEVLDRCLKQVEFYFSEF
NFPYDRFLRTTAEKNDGWVPISTIATFNRMKKYRPVDKVIEALRSSEILEVSADGENV
KRRVPLDLTAARNARIEQNQRTLAVMNFPHEDVEASQIPELQENLEAFFKKLGEINQV
RLRRDHRNKKFNGTVLVEFKTIPECEAFLKSYSNDDESNEILSYEGKKLSVLTKKQFD
LQREASKSKNFSGRSRSFNGHKKKNLPKFPKNKKKNGKEESKEDSSAIADDDEEHKE"
gene complement(365068..365874)
/gene="KNH1"
/locus_tag="YDL049C"
/db_xref="GeneID:851511"
mRNA complement(365068..365874)
/gene="KNH1"
/locus_tag="YDL049C"
/product="Knh1p"
/transcript_id="NM_001180108.1"
/db_xref="GI:296143314"
/db_xref="GeneID:851511"
CDS complement(365068..365874)
/gene="KNH1"
/locus_tag="YDL049C"
/note="Protein with similarity to Kre9p, which is involved
in cell wall beta 1,6-glucan synthesis; overproduction
suppresses growth defects of a kre9 null mutant; required
for propionic acid resistance"
/codon_start=1
/product="Knh1p"
/protein_id="NP_010234.1"
/db_xref="GI:6320154"
/db_xref="SGD:S000002207"
/db_xref="GeneID:851511"
/translation="MLIVLFLTLFCSVVFRTAYCDVAIVAPEPNSVYDLSGTSQAVVK
VKWMHTDNTPQEKDFVRYTFTLCSGTNAMIEAMATLQTLSASDLTDNEFNAIIENTVG
TDGVYFIQVFAQTAIGYTIHYTNRFKLKGMIGTKAANPSMITIAPEAQTRITTGDVGA
TIDSKSFTVPYNLQTGVVKYAPMQLQPATKVTAKTWKRKYATSEVTYYYTLRNSVDQH
TTVTPGWSYIITADSNYATPAPMPADNGGWYNPRKRLSLTARKVNALRHR"
gene complement(366739..368211)
/gene="STP4"
/locus_tag="YDL048C"
/db_xref="GeneID:851512"
mRNA complement(366739..368211)
/gene="STP4"
/locus_tag="YDL048C"
/product="Stp4p"
/transcript_id="NM_001180107.1"
/db_xref="GI:296143315"
/db_xref="GeneID:851512"
CDS complement(366739..368211)
/gene="STP4"
/locus_tag="YDL048C"
/note="Protein containing a Kruppel-type zinc-finger
domain; has similarity to Stp1p, Stp2p, and Stp3p;
predicted to be a transcription factor; relative
distribution to the nucleus increases upon DNA replication
stress"
/codon_start=1
/product="Stp4p"
/protein_id="NP_010235.1"
/db_xref="GI:6320155"
/db_xref="SGD:S000002206"
/db_xref="GeneID:851512"
/translation="MLVSSSFASSIDSVMSHETMSLRRNPPFIDTPEKMPNPTASPNG
TIHHLIDPSLPLLSSTTSSSRSTLSSTLNSPPPPPLTTSYSSYNSSACQSITSSPTDN
TALAHNSKCYFPHSLSPTPLSSNSSSHVILPPISSFTNLITVAEREFNGRSNSLHANF
TSPVPRTVLDHHRHELTFCNPNNTTGFKTITPSPPTQHQSILPTAVDNVPRSKSVSSL
PVSGFPPLIVKQQQQQQLNSSSSASALPSIHSPLTNEHTSRYSSSLKDSAKITKQRKK
KECPICHNFYANLSTHKSTHLTPEDRPHKCPICQRGFARNNDLIRHKKRHWKDEFMQI
YARESDNNSGADDQDDTARTSANNDSDDSNDKLAASSSSEETKLLKKNQLKSLYKIKG
AFKCPYNSTLINLDMEVYPHKSRSLYFEPINCHQTGVFSRCDTFKNHLKALHFEYPPK
TKKEDRGVVPGKCKHCGLQFPNVDVWLNKHVGKGCGYSYH"
gene 369771..370706
/gene="SIT4"
/locus_tag="YDL047W"
/db_xref="GeneID:851513"
mRNA 369771..370706
/gene="SIT4"
/locus_tag="YDL047W"
/product="Sit4p"
/transcript_id="NM_001180106.1"
/db_xref="GI:296143316"
/db_xref="GeneID:851513"
CDS 369771..370706
/gene="SIT4"
/locus_tag="YDL047W"
/EC_number="3.1.3.16"
/note="Type 2A-related serine-threonine phosphatase that
functions in the G1/S transition of the mitotic cycle;
cytoplasmic and nuclear protein that modulates functions
mediated by Pkc1p including cell wall and actin
cytoskeleton organization"
/codon_start=1
/product="Sit4p"
/protein_id="NP_010236.1"
/db_xref="GI:6320156"
/db_xref="SGD:S000002205"
/db_xref="GeneID:851513"
/translation="MVSRGPDEWLETIKKCQALTENEMKQLCEMVKELLMEESNIQPV
QTPVTVCGDIHGQFHDLLELFRTAGGFPDDINYIFLGDYVDRGYYSLETFTLLMCLKV
KYPAKITLVRGNHESRQITQVYGFYEECLNKYGSTTVWKYCCQVFDFLTLAAIIDGKI
LCVHGGLSPEIRMLDQIRVLSRAQEVPHEGGFSDLLWSDPDNVEAWQVSPRGAGWLFG
SKVAREFNHVNGLNLIARAHQLVMEGFKYHFPEKDVVTVWSAPNYCYRCGNVASVMKV
DEDLEPTFKIFSAVPDDYIRESTANHNNQRAGYFL"
gene 371240..371761
/gene="NPC2"
/locus_tag="YDL046W"
/db_xref="GeneID:851514"
mRNA 371240..371761
/gene="NPC2"
/locus_tag="YDL046W"
/product="Npc2p"
/transcript_id="NM_001180105.1"
/db_xref="GI:296143317"
/db_xref="GeneID:851514"
CDS 371240..371761
/gene="NPC2"
/locus_tag="YDL046W"
/note="Functional homolog of human NPC2/He1, which is a
cholesterol-binding protein whose deficiency causes
Niemann-Pick type C2 disease involving retention of
cholesterol in lysosomes"
/codon_start=1
/product="Npc2p"
/protein_id="NP_010237.1"
/db_xref="GI:6320157"
/db_xref="SGD:S000002204"
/db_xref="GeneID:851514"
/translation="MTHSLKALFALLFLYTAAVNAGVIGIFNALPPPNTKPINGESPL
YQCDILDKQLVEIKEVNLDPNPPVRGENLTISANGEVFETIEEGAYIDVEVRLGYIRL
LSQTFDLCETLEDNDIEGLSCPIEPGEYNIKKIVEIPGEVPPGKYVVVARAYTEKDDL
ITCLTGEVIFPPR"
gene 372248..372535
/gene="MRP10"
/locus_tag="YDL045W-A"
/db_xref="GeneID:851515"
mRNA 372248..372535
/gene="MRP10"
/locus_tag="YDL045W-A"
/product="mitochondrial 37S ribosomal protein YmS-T"
/transcript_id="NM_001184304.1"
/db_xref="GI:296143318"
/db_xref="GeneID:851515"
CDS 372248..372535
/gene="MRP10"
/locus_tag="YDL045W-A"
/note="Mitochondrial ribosomal protein of the small
subunit; contains twin cysteine-x9-cysteine motifs"
/codon_start=1
/product="mitochondrial 37S ribosomal protein YmS-T"
/protein_id="NP_010238.1"
/db_xref="GI:6320158"
/db_xref="SGD:S000006430"
/db_xref="GeneID:851515"
/translation="MSGKPPVYRLPPLPRLKVKKPIIRQEANKCLVLMSNLLQCWSSY
GHMSPKCAGLVTELKSCTSESALGKRNNVQKSNINYHAARLYDRINGKPHD"
gene complement(372688..373608)
/gene="FAD1"
/locus_tag="YDL045C"
/db_xref="GeneID:851516"
mRNA complement(372688..373608)
/gene="FAD1"
/locus_tag="YDL045C"
/product="FMN adenylyltransferase"
/transcript_id="NM_001180104.1"
/db_xref="GI:296143319"
/db_xref="GeneID:851516"
CDS complement(372688..373608)
/gene="FAD1"
/locus_tag="YDL045C"
/EC_number="2.7.7.2"
/note="Flavin adenine dinucleotide (FAD) synthetase,
performs the second step in synthesis of FAD from
riboflavin"
/codon_start=1
/product="FMN adenylyltransferase"
/protein_id="NP_010239.1"
/db_xref="GI:6320159"
/db_xref="SGD:S000002203"
/db_xref="GeneID:851516"
/translation="MQLSKAAEMCYEITNSYLHIDQKSQIIASTQEAIRLTRKYLLSE
IFVRWSPLNGEISFSYNGGKDCQVLLLLYLSCLWEYFFIKAQNSQFDFEFQSFPMQRL
PTVFIDQEETFPTLENFVLETSERYCLSLYESQRQSGASVNMADAFRDFIKIYPETEA
IVIGIRHTDPFGEALKPIQRTDSNWPDFMRLQPLLHWDLTNIWSFLLYSNEPICGLYG
KGFTSIGGINNSLPNPHLRKDSNNPALHFEWEIIHAFGKDAEGERSSAINTSPISVVD
KERFSKYHDNYYPGWYLVDDTLERAGRIKN"
gene complement(373967..375289)
/gene="MTF2"
/locus_tag="YDL044C"
/gene_synonym="NAM1"
/db_xref="GeneID:851517"
mRNA complement(373967..375289)
/gene="MTF2"
/locus_tag="YDL044C"
/gene_synonym="NAM1"
/product="Mtf2p"
/transcript_id="NM_001180103.1"
/db_xref="GI:296143320"
/db_xref="GeneID:851517"
CDS complement(373967..375289)
/gene="MTF2"
/locus_tag="YDL044C"
/gene_synonym="NAM1"
/note="Mitochondrial matrix protein that interacts with an
N-terminal region of mitochondrial RNA polymerase (Rpo41p)
and couples RNA processing and translation to
transcription"
/codon_start=1
/product="Mtf2p"
/protein_id="NP_010240.1"
/db_xref="GI:6320160"
/db_xref="SGD:S000002202"
/db_xref="GeneID:851517"
/translation="MIRTSSILKNCNYRYIHCIHRCLLNEANLKDRKTHNVERVSNEK
TFEQALEEERKVFGELFEAGARVENMRHTNASKIIDKYYNGLQDNSEGTSVKKEKIVF
NHSQRAQRKLPNKDHEFLKETAGNDYVYERAEPSAISTKTISEQTRTLLEKIFDEDNS
INKSNRELLNLNLRKGSGMEALRQPVAHSNVKFSEEVMQEIGNKIRYQTTLDQVLEPH
IDYLREAVKSDYDLLRYLKQSLDIYKKRNKDLELKMNAESSNIFEDIRSACINKPAEL
PKPLAMTLPYIIVKSLRLGDFDFPADRKYTLISYVYNECKNNMDASLYLTICNVDFYN
LLVQLLWENFQEIRYLRRVVTEMSVNGVIGNIETVDILDKIVKEMRSLNEDVFLEAGE
QLSADEEVSSSANKIVNVGVLWNKDTNNDLLIVENYLKSLKKNLTRDR"
gene complement(375680..376480)
/gene="PRP11"
/locus_tag="YDL043C"
/gene_synonym="RNA11"
/db_xref="GeneID:851518"
mRNA complement(375680..376480)
/gene="PRP11"
/locus_tag="YDL043C"
/gene_synonym="RNA11"
/product="Prp11p"
/transcript_id="NM_001180102.1"
/db_xref="GI:296143321"
/db_xref="GeneID:851518"
CDS complement(375680..376480)
/gene="PRP11"
/locus_tag="YDL043C"
/gene_synonym="RNA11"
/note="Subunit of the SF3a splicing factor complex,
required for spliceosome assembly"
/codon_start=1
/product="Prp11p"
/protein_id="NP_010241.1"
/db_xref="GI:6320161"
/db_xref="SGD:S000002201"
/db_xref="GeneID:851518"
/translation="MNYLEGVGSKKGGGGIASESQFNLQRRKEVESLLSKGENVPYTF
QDEKDDQVRSNPYIYKNHSGKLVCKLCNTMHMSWSSVERHLGGKKHGLNVLRRGISIE
KSSLGREGQTTHDFRQQQKIIEAKQSLKNNGTIPVCKIATVKNPKNGSVGLAIQVNYS
SEVKENSVDSDDKAKVPPLIRIVSGLELSDTKQKGKKFLVIAYEPFENIAIELPPNEI
LFSENNDMDNNNDGVDELNKKCTFWDAISKLYYVQFFFKQAEQEQADV"
gene complement(376757..378445)
/gene="SIR2"
/locus_tag="YDL042C"
/gene_synonym="MAR1"
/db_xref="GeneID:851520"
mRNA complement(376757..378445)
/gene="SIR2"
/locus_tag="YDL042C"
/gene_synonym="MAR1"
/product="Sir2p"
/transcript_id="NM_001180101.1"
/db_xref="GI:296143322"
/db_xref="GeneID:851520"
CDS complement(376757..378445)
/gene="SIR2"
/locus_tag="YDL042C"
/gene_synonym="MAR1"
/EC_number="3.5.1.-"
/note="Conserved NAD+ dependent histone deacetylase of the
Sirtuin family; involved in regulation of lifespan; plays
roles in silencing at HML, HMR, telomeres, and the rDNA
locus; negatively regulates initiation of DNA replication;
functions as a regulator of autophagy like mammalian
homolog SIRT1, and also of mitophagy"
/codon_start=1
/product="Sir2p"
/protein_id="NP_010242.1"
/db_xref="GI:6320163"
/db_xref="SGD:S000002200"
/db_xref="GeneID:851520"
/translation="MTIPHMKYAVSKTSENKVSNTVSPTQDKDAIRKQPDDIINNDEP
SHKKIKVAQPDSLRETNTTDPLGHTKAALGEVASMELKPTNDMDPLAVSAASVVSMSN
DVLKPETPKGPIIISKNPSNGIFYGPSFTKRESLNARMFLKYYGAHKFLDTYLPEDLN
SLYIYYLIKLLGFEVKDQALIGTINSIVHINSQERVQDLGSAISVTNVEDPLAKKQTV
RLIKDLQRAINKVLCTRLRLSNFFTIDHFIQKLHTARKILVLTGAGVSTSLGIPDFRS
SEGFYSKIKHLGLDDPQDVFNYNIFMHDPSVFYNIANMVLPPEKIYSPLHSFIKMLQM
KGKLLRNYTQNIDNLESYAGISTDKLVQCHGSFATATCVTCHWNLPGERIFNKIRNLE
LPLCPYCYKKRREYFPEGYNNKVGVAASQGSMSERPPYILNSYGVLKPDITFFGEALP
NKFHKSIREDILECDLLICIGTSLKVAPVSEIVNMVPSHVPQVLINRDPVKHAEFDLS
LLGYCDDIAAMVAQKCGWTIPHKKWNDLKNKNFKCQEKDKGVYVVTSDEHPKTL"
gene complement(378874..381438)
/gene="NAT1"
/locus_tag="YDL040C"
/gene_synonym="AAA1; NAA15"
/db_xref="GeneID:851521"
mRNA complement(378874..381438)
/gene="NAT1"
/locus_tag="YDL040C"
/gene_synonym="AAA1; NAA15"
/product="Nat1p"
/transcript_id="NM_001180099.1"
/db_xref="GI:296143323"
/db_xref="GeneID:851521"
CDS complement(378874..381438)
/gene="NAT1"
/locus_tag="YDL040C"
/gene_synonym="AAA1; NAA15"
/note="Subunit of the N-terminal acetyltransferase NatA
(Nat1p, Ard1p, Nat5p); N-terminally acetylates many
proteins, which influences multiple processes such as the
cell cycle, heat-shock resistance, mating, sporulation,
and telomeric silencing"
/codon_start=1
/product="Nat1p"
/protein_id="NP_010244.1"
/db_xref="GI:6320164"
/db_xref="SGD:S000002198"
/db_xref="GeneID:851521"
/translation="MSRKRSTKPKPAAKIALKKENDQFLEALKLYEGKQYKKSLKLLD
AILKKDGSHVDSLALKGLDLYSVGEKDDAASYVANAIRKIEGASASPICCHVLGIYMR
NTKEYKESIKWFTAALNNGSTNKQIYRDLATLQSQIGDFKNALVSRKKYWEAFLGYRA
NWTSLAVAQDVNGERQQAINTLSQFEKLAEGKISDSEKYEHSECLMYKNDIMYKAASD
NQDKLQNVLKHLNDIEPCVFDKFGLLERKATIYMKLGQLKDASIVYRTLIKRNPDNFK
YYKLLEVSLGIQGDNKLKKALYGKLEQFYPRCEPPKFIPLTFLQDKEELSKKLREYVL
PQLERGVPATFSNVKPLYQRRKSKVSPLLEKIVLDYLSGLDPTQDPIPFIWTNYYLSQ
HFLFLKDFPKAQEYIDAALDHTPTLVEFYILKARILKHLGLMDTAAGILEEGRQLDLQ
DRFINCKTVKYFLRANNIDKAVEVASLFTKNDDSVNGIKDLHLVEASWFIVEQAEAYY
RLYLDRKKKLDDLASLKKEVESDKSEQIANDIKENQWLVRKYKGLALKRFNAIPKFYK
QFEDDQLDFHSYCMRKGTPRAYLEMLEWGKALYTKPMYVRAMKEASKLYFQMHDDRLK
RKSDSLDENSDEIQNNGQNSSSQKKKAKKEAAAMNKRKETEAKSVAAYPSDQDNDVFG
EKLIETSTPMEDFATEFYNNYSMQVREDERDYILDFEFNYRIGKLALCFASLNKFAKR
FGTTSGLFGSMAIVLLHATRNDTPFDPILKKVVTKSLEKEYSENFPLNEISNNSFDWL
NFYQEKFGKNDINGLLFLYRYRDDVPIGSSNLKEMIISSLSPLEPHSQNEILQYYL"
gene complement(381985..384081)
/gene="PRM7"
/locus_tag="YDL039C"
/gene_synonym="YDL038C"
/db_xref="GeneID:851522"
mRNA complement(381985..384081)
/gene="PRM7"
/locus_tag="YDL039C"
/gene_synonym="YDL038C"
/product="Prm7p"
/transcript_id="NM_001180098.1"
/db_xref="GI:296143324"
/db_xref="GeneID:851522"
CDS complement(381985..384081)
/gene="PRM7"
/locus_tag="YDL039C"
/gene_synonym="YDL038C"
/note="Pheromone-regulated protein, predicted to have one
transmembrane segment; promoter contains Gcn4p binding
elements"
/codon_start=1
/product="Prm7p"
/protein_id="NP_010245.2"
/db_xref="GI:269970297"
/db_xref="SGD:S000002197"
/db_xref="GeneID:851522"
/translation="MYRTRSSDEVTTSTDLTSSSDVATSVDPTTSVISSTSADPTTSA
DSTTSTVQTTSAGPSNNIGNSTLANSTTFAVSSTSIDPTSSSDVITSTVQTTSIEPTT
SLVSSNDITTSTSLNISVVISTSTDSTSLIESTTTVGPHASSSVAGMYRTRSSDEVTT
STDPTSSSDVATSADPTSSSAVTTLVDPTTSVVISTSVDQTSSSDVATSVDPTTSVIS
STSADPTTSADSTTSTVQTTSVDPTSSVVSSAPVDPASSVVSLTSSYPTSSSTVTISA
NSNGSATLAAQTTSIDPVSSIVSSSGATTIISSASIDPASSVVSSTSSEPTSFIVSST
SVYSTRPSGPTTSTDLATFSDTIILRVSTTSTSQDTQTVSSSLTDMVSSTGSADLSVS
SIQRSQVDPSTFAVSNSPVYPTASTGSTSTGIPIASESLSLSRQQGISATSSSSIVTL
TPVDSASSSRSSATSIIKPNMPVSSNDSKTQSSVSVVDAFQSTKSSYPSITSADPTTL
ASENGLVGSSSSAHPITLDRTYASAHASVTDIVSRVTDSTRHTTLVTSNINIQSEVGN
PNYSGPKDTTITKQSAFMTSPASTSTISNVQSTASVMNHSIEDNISAAASLESVSGTS
TKDYSSQSSAIHYTNSFTTTTTNAFITSKHSIAAVSTGAITSSASISLIMEGSANIEA
VGKLVWLAAALPLAFI"
gene complement(384601..385587)
/gene="BSC1"
/locus_tag="YDL037C"
/db_xref="GeneID:851524"
mRNA complement(384601..385587)
/gene="BSC1"
/locus_tag="YDL037C"
/product="Bsc1p"
/transcript_id="NM_001180096.1"
/db_xref="GI:296143325"
/db_xref="GeneID:851524"
CDS complement(384601..385587)
/gene="BSC1"
/locus_tag="YDL037C"
/note="Protein of unconfirmed function, similar to cell
surface flocculin Muc1p; ORF exhibits genomic organization
compatible with a translational readthrough-dependent mode
of expression"
/codon_start=1
/product="Bsc1p"
/protein_id="NP_010247.1"
/db_xref="GI:6320167"
/db_xref="SGD:S000002195"
/db_xref="GeneID:851524"
/translation="MSQQNILHYDMDVTSVSWVKDNTYQITIHVKAVKDIPLKYLWSL
KIIGVNGPSSTVQLYGKNEKTYLISDPTDFTSTFQVYAYPSSDGCTVWMPNFQIQFEY
LQGDAAQYWQTWQWGTTTFDLSTGCNNYDNQGHSQTDFPGFYWTYQCKGNNDGTCTKA
SSSSITTSSITTSSTTTSSTTTSSTTTSSSTTSSSTTSSSTTSSSTTSSSTTSSSTTS
SSTTSSSTTSSSTTSSSTTSSSTTSSSTKTSTTTSSTVKSSSTTSIDFTTSVDSHTSS
SVADIYRSRTSTDVTTLAASTSPFSSFTSSDSSSSSDVTSSTIQTTSVDPTT"
gene complement(387513..388901)
/gene="PUS9"
/locus_tag="YDL036C"
/db_xref="GeneID:851525"
mRNA complement(387513..388901)
/gene="PUS9"
/locus_tag="YDL036C"
/product="pseudouridine synthase PUS9"
/transcript_id="NM_001180095.1"
/db_xref="GI:296143326"
/db_xref="GeneID:851525"
CDS complement(387513..388901)
/gene="PUS9"
/locus_tag="YDL036C"
/note="Mitochondrial tRNA:pseudouridine synthase,
catalyzes the formation of pseudouridine at position 32 in
mitochondrial tRNAs; contains an N-terminal mitochondrial
targeting sequence"
/codon_start=1
/product="pseudouridine synthase PUS9"
/protein_id="NP_010248.1"
/db_xref="GI:6320168"
/db_xref="SGD:S000002194"
/db_xref="GeneID:851525"
/translation="MQRNNRLRNLFTVPVIMARQLKRNALSAGLAFAGNATSNEFDEH
LQNEVEREREIQKKKKIKRTQSKKSPDLINKSTFQSRTIGSKKEKHRQLDPEYEIVID
GPLRKIKPYHFTYRTFCKERWRDKKLVDVFISEFRDRESEYYKRTIENGDVHINDETA
DLSTVIRNGDLITHQVHRHEPPVTSRPIKVIFEDDNIMVIDKPSGIPVHPTGRYRFNT
ITKMLQNNLGFVVNPCNRLDRLTSGLMFLAKTPKGADNIGDQLKAREVTKEYVAKVVG
EFPETEVIVEKPLKLIEPRLALNAVCQMDEKGAKHAKTVFNRISYDGKTSIVKCKPLT
GRSHQIRVHLQYLGHPIANDPIYSNDEVWGNNLGKGGQADFDIVITKLDEIGKRKPAK
SWFHSNGGYGEVLRQEKCSICESDLYTDPGPNDLDLWLHAYLYESTETEEGTEKKKWC
YKTEYPEWALRR"
gene complement(389172..392057)
/gene="GPR1"
/locus_tag="YDL035C"
/db_xref="GeneID:851527"
mRNA complement(389172..392057)
/gene="GPR1"
/locus_tag="YDL035C"
/product="Gpr1p"
/transcript_id="NM_001180094.1"
/db_xref="GI:296143327"
/db_xref="GeneID:851527"
CDS complement(389172..392057)
/gene="GPR1"
/locus_tag="YDL035C"
/note="Plasma membrane G protein coupled receptor (GPCR)
that interacts with the heterotrimeric G protein alpha
subunit, Gpa2p, and with Plc1p; sensor that integrates
nutritional signals with the modulation of cell fate via
PKA and cAMP synthesis"
/codon_start=1
/product="Gpr1p"
/protein_id="NP_010249.1"
/db_xref="GI:6320170"
/db_xref="SGD:S000002193"
/db_xref="GeneID:851527"
/translation="MITEGFPPNLNALKGSSLLEKRVDSLRQLNTTTVNQLLGLPGMT
STFTAPQLLQLRIIAITASAVSLIAGCLGMFFLSKMDKRRKVFRHDLIAFLIICDFLK
AFILMIYPMIILINNSVYATPAFFNTLGWFTAFAIEGADMAIMIFAIHFAILIFKPNW
KWRNKRSGNMEGGLYKKRSYIWPITALVPAILASLAFINYNKLNDDSDTTIILDNNNY
NFPDSPRQGGYKPWSAWCYLPPKPYWYKIVLSWGPRYFIIIFIFAVYLSIYIFITSES
KRIKAQIGDFNHNVLEEEKEKKKLFGLGHWGKAKWYFRSYFKLPLLHLLRNLKNFFTI
SFIDPNEETDDSGSSNGTFNFGESSNEIPTLFRKTNTGSDENVSASGGVRLLDYNSAK
PLDMSKYAMSEQPDLERNNPFDCENDITLNPSELVSKQKEHKVTFSVENEGLDTRKSS
MLGHQTFSCQNSLESPLAMYDNKNDNSDITSNIKEKGGIINNNSNNDDDDNNNNNDND
NDNNNSNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNSNNIKNNVDNNNTNPADNIPTL
SNEAFTPSQQFSQERVNNNADRCENSSFTNVQQHFQAQTYKQMKKRRAQIQKNLRAIF
IYPLSYIGIWLFPIIADALQYNHEIKHGPTMWVTYIDTCVRPLSCLVDVIVYLFKEKP
WNYSWAKTESKYLIEKYILKGELGEKEILKFCHSNWGKRGWYYRGKWKKRKCWKYSTN
PLKRILWFVERFFKQLFELKLHFSFYDNCDDFEYWENYYSAKDSNDNKRTESDETKTN
SSDRSLPSNSLELQAMLNNITAEEVEVPLFWRIIHHIPMLGGIDLDELNRLLKIRYNN
DHFSLPGLKFALNQNKSHDKHQDVSTNSMVKSSFFSSNIVTNDDENSIEEDKNLRYSD
ASASENYLVKPTIPGTTPDPIIEAQNDNDSSDSSGIDLIAFLRNGPL"
gene complement(392659..393912)
/gene="SLM3"
/locus_tag="YDL033C"
/gene_synonym="MTO2; MTU1"
/db_xref="GeneID:851529"
mRNA complement(392659..393912)
/gene="SLM3"
/locus_tag="YDL033C"
/gene_synonym="MTO2; MTU1"
/product="Slm3p"
/transcript_id="NM_001180092.1"
/db_xref="GI:296143328"
/db_xref="GeneID:851529"
CDS complement(392659..393912)
/gene="SLM3"
/locus_tag="YDL033C"
/gene_synonym="MTO2; MTU1"
/EC_number="2.1.1.61"
/note="tRNA-specific 2-thiouridylase, responsible for
2-thiolation of the wobble base of mitochondrial tRNAs;
human ortholog is implicated in myoclonus epilepsy
associated with ragged red fibers (MERRF)"
/codon_start=1
/product="Slm3p"
/protein_id="NP_010251.1"
/db_xref="GI:6320172"
/db_xref="SGD:S000002191"
/db_xref="GeneID:851529"
/translation="MLARYLNLIGRRSASPYRPQRLPAKFDNVIVAMSSGVDSSVAAA
LFAGEFPNTRGVYMQNWSESQSLDDPGKEPCYERDWRDVNRVAKHLNIRVDKVNFEQD
YWIDVFEPMLRGYSEGSTPNPDIGCNKFVKFGKLREWLDEKYGTGNYWLVTGHYARVM
QEMNGKGLFHLLRSIYRPKDQSYYLSQINSTVLSSLLLPIGHLTKPEVRDLAKYAGLP
TAEKPDSQGICFVNNSQHGKFKNFLKHYLPSSPGDIITVDPQSGAKTTWGRHDGLWSY
TIGQKVGISMPQADPNYQGTWFVSEKLRDTNEILIVRGRDNPALYSDTMRIENFSSLG
PREDTINAFQNTGALTLQFRSLQVPVQIKSCKLNRSADNLDITIHLASKQRAITPGQS
CCLYIDDRVLGSGPISHVNNNDTHA"
gene 394217..397204
/gene="DBP10"
/locus_tag="YDL031W"
/db_xref="GeneID:851530"
mRNA 394217..397204
/gene="DBP10"
/locus_tag="YDL031W"
/product="Dbp10p"
/transcript_id="NM_001180090.2"
/db_xref="GI:330443504"
/db_xref="GeneID:851530"
CDS 394217..397204
/gene="DBP10"
/locus_tag="YDL031W"
/EC_number="3.6.1.-"
/note="Putative ATP-dependent RNA helicase of the DEAD-box
protein family, constituent of 66S pre-ribosomal
particles; essential protein involved in ribosome
biogenesis"
/codon_start=1
/product="Dbp10p"
/protein_id="NP_010253.2"
/db_xref="GI:330443505"
/db_xref="SGD:S000002189"
/db_xref="GeneID:851530"
/translation="MAGVQKRKRDLEDQDDNGSEEDDIAFDIANEIALNDSESDANDS
DSEVEADYGPNDVQDVIEYSSDEEEGVNNKKKAENKDIKKKKNSKKEIAAFPMLEMSD
DENNASGKTQTGDDEDDVNEYFSTNNLEKTKHKKGSFPSFGLSKIVLNNIKRKGFRQP
TPIQRKTIPLILQSRDIVGMARTGSGKTAAFILPMVEKLKSHSGKIGARAVILSPSRE
LAMQTFNVFKDFARGTELRSVLLTGGDSLEEQFGMMMTNPDVIIATPGRFLHLKVEMN
LDLKSVEYVVFDEADRLFEMGFQEQLNELLASLPTTRQTLLFSATLPNSLVDFVKAGL
VNPVLVRLDAETKVSENLEMLFLSSKNADREANLLYILQEIIKIPLATSEQLQKLQNS
NNEADSDSDDENDRQKKRRNFKKEKFRKQKMPAANELPSEKATILFVPTRHHVEYISQ
LLRDCGYLISYIYGTLDQHARKRQLYNFRAGLTSILVVTDVAARGVDIPMLANVINYT
LPGSSKIFVHRVGRTARAGNKGWAYSIVAENELPYLLDLELFLGKKILLTPMYDSLVD
VMKKRWIDEGKPEYQFQPPKLSYTKRLVLGSCPRLDVEGLGDLYKNLMSSNFDLQLAK
KTAMKAEKLYYRTRTSASPESLKRSKEIISSGWDAQNAFFGKNEEKEKLDFLAKLQNR
RNKETVFEFTRNPDDEMAVFMKRRRKQLAPIQRKATERRELLEKERMAGLSHSIEDEI
LKGDDGETGYTVSEDALKEFEDADQLLEAQENENKKKKKPKSFKDPTFFLSHYAPAGD
IQDKQLQITNGFANDAAQAAYDLNSDDKVQVHKQTATVKWDKKRKKYVNTQGIDNKKY
IIGESGQKIAASFRSGRFDDWSKARNLKPLKVGSRETSIPSNLLEDPSQGPAANGRTV
RGKFKHKQMKAPKMPDKHRDNYYSQKKKVEKALQSGISVKGYNNAPGLRSELKSTEQI
RKDRIIAEKKRAKNARPSKKRKF"
gene 397537..399129
/gene="PRP9"
/locus_tag="YDL030W"
/db_xref="GeneID:851531"
mRNA 397537..399129
/gene="PRP9"
/locus_tag="YDL030W"
/product="Prp9p"
/transcript_id="NM_001180089.1"
/db_xref="GI:296143330"
/db_xref="GeneID:851531"
CDS 397537..399129
/gene="PRP9"
/locus_tag="YDL030W"
/note="Subunit of the SF3a splicing factor complex,
required for spliceosome assembly; acts after the
formation of the U1 snRNP-pre-mRNA complex"
/codon_start=1
/product="Prp9p"
/protein_id="NP_010254.1"
/db_xref="GI:6320174"
/db_xref="SGD:S000002188"
/db_xref="GeneID:851531"
/translation="MNLLETRRSLLEEMEIIENAIAERIQRNPELYYHYIQESSKVFP
DTKLPRSSLIAENKIYKFKKVKRKRKQIILQQHEINIFLRDYQEKQQTFNKINRPEET
QEDDKDLPNFERKLQQLEKELKNEDENFELDINSKKDKYALFSSSSDPSRRTNILSDR
ARDLDLNEIFTRDEQYGEYMELEQFHSLWLNVIKRGDCSLLQFLDILELFLDDEKYLL
TPPMDRKNDRYMAFLLKLSKYVETFFFKSYALLDAAAVENLIKSDFEHSYCRGSLRSE
AKGIYCPFCSRWFKTSSVFESHLVGKIHKKNESKRRNFVYSEYKLHRYLKYLNDEFSR
TRSFVERKLAFTANERMAEMDILTQKYEAPAYDSTEKEGAEQVDGEQRDGQLQEEHLS
GKSFDMPLGPDGLPMPYWLYKLHGLDREYRCEICSNKVYNGRRTFERHFNEERHIYHL
RCLGIEPSSVFKGITKIKEAQELWKNMQGQSQLTSIAAVPPKPNPSQLKVPTELELEE
EDEEGNVMSKKVYDELKKQGLV"
gene 399340..400638
/gene="ARP2"
/locus_tag="YDL029W"
/gene_synonym="ACT2"
/db_xref="GeneID:851532"
mRNA join(399340..399361,399485..400638)
/gene="ARP2"
/locus_tag="YDL029W"
/gene_synonym="ACT2"
/product="actin-related protein 2"
/transcript_id="NM_001180088.1"
/db_xref="GI:296143331"
/db_xref="GeneID:851532"
CDS join(399340..399361,399485..400638)
/gene="ARP2"
/locus_tag="YDL029W"
/gene_synonym="ACT2"
/note="Essential component of the Arp2/3 complex, which is
a highly conserved actin nucleation center required for
the motility and integrity of actin patches; involved in
endocytosis and membrane growth and polarity"
/codon_start=1
/product="actin-related protein 2"
/protein_id="NP_010255.1"
/db_xref="GI:6320175"
/db_xref="SGD:S000002187"
/db_xref="GeneID:851532"
/translation="MDPHNPIVLDQGTGFVKIGRAGENFPDYTFPSIVGRPILRAEER
ASVATPLKDIMIGDEASEVRSYLQISYPMENGIIKNWTDMELLWDYAFFEQMKLPSTS
NGKILLTEPPMNPLKNREKMCEVMFEKYDFGGVYVAIQAVLALYAQGLSSGVVVDSGD
GVTHIVPVYESVVLSHLTRRLDVAGRDVTRHLIDLLSRRGYAFNRTADFETVRQIKEK
LCYVSYDLDLDTKLARETTALVESYELPDGRTIKVGQERFEAPECLFQPGLVDVEQPG
VGELLFNTVQSADVDIRSSLYKAIVLSGGSSMYPGLPSRLEKELKQLWFSRVLHNDPS
RLDKFKVRIEDPPRRKHMVFIGGAVLASIMADKDHMWLSKQEWQESGPSAMTKFGPR"
gene complement(400997..403291)
/gene="MPS1"
/locus_tag="YDL028C"
/gene_synonym="RPK1"
/db_xref="GeneID:851533"
mRNA complement(400997..403291)
/gene="MPS1"
/locus_tag="YDL028C"
/gene_synonym="RPK1"
/product="Mps1p"
/transcript_id="NM_001180087.2"
/db_xref="GI:330443506"
/db_xref="GeneID:851533"
CDS complement(400997..403291)
/gene="MPS1"
/locus_tag="YDL028C"
/gene_synonym="RPK1"
/EC_number="2.7.12.1"
/note="Dual-specificity kinase required for spindle pole
body (SPB) duplication and spindle checkpoint function;
substrates include SPB proteins Spc42p, Spc110p, and
Spc98p, mitotic exit network protein Mob1p, and checkpoint
protein Mad1p"
/codon_start=1
/product="Mps1p"
/protein_id="NP_010256.2"
/db_xref="GI:330443507"
/db_xref="SGD:S000002186"
/db_xref="GeneID:851533"
/translation="MSTNSFHDYVDLKSRTNTRQFSDDEEFTTPPKLSNFGSALLSHT
EKTSASEILSSHNNDKIANRLEEMDRSSSRSHPPPSMGNLTSGHTSTSSHSTLFGRYL
RNNHQTSMTTMNTSDIEINVGNSLDKSFERIRNLRQNMKEDITAKYAERRSKRFLISN
RTTKLGPAKRAMTLTNIFDEDVPNSPNQPINARETVELPLEDSHQTNFKETKRNTDYD
SIDFGDLNPIQYIKKHNLPTSDLPLISQIYFDKQREENRQAALRKHSSRELLYKSRSS
SSSLSSNNLLANKDNSITSNNGSQPRRKVSTGSSSSKSSIEIRRALKENIDTSNNSNF
NSPIHKIYKGISRNKDSDSEKREVLRNISINANHADNLLQQENKRLKRSLDDAITNEN
INSKNLEVFYHRPAPKPPVTKKVEIVEPAKSASLSNNRNIITVNDSQYEKIELLGRGG
SSRVYKVKGSGNRVYALKRVSFDAFDDSSIDGFKGEIELLEKLKDQKRVIQLLDYEMG
DGLLYLIMECGDHDLSQILNQRSGMPLDFNFVRFYTKEMLLCIKVVHDAGIVHSDLKP
ANFVLVKGILKIIDFGIANAVPEHTVNIYRETQIGTPNYMAPEALVAMNYTQNSENQH
EGNKWKVGRPSDMWSCGCIIYQMIYGKPPYGSFQGQNRLLAIMNPDVKIPFPEHTSNN
EKIPKSAIELMKACLYRNPDKRWTVDKVLSSTFLQPFMISGSIMEDLIRNAVRYGSEK
PHISQDDLNDVVDTVLRKFADYKI"
gene complement(403695..404957)
/locus_tag="YDL027C"
/db_xref="GeneID:851535"
mRNA complement(403695..404957)
/locus_tag="YDL027C"
/product="hypothetical protein"
/transcript_id="NM_001180086.1"
/db_xref="GI:296143333"
/db_xref="GeneID:851535"
CDS complement(403695..404957)
/locus_tag="YDL027C"
/note="hypothetical protein; the authentic, non-tagged
protein is detected in highly purified mitochondria in
high-throughput studies; YDL027C is not an essential gene"
/codon_start=1
/product="hypothetical protein"
/protein_id="NP_010257.1"
/db_xref="GI:6320178"
/db_xref="SGD:S000002185"
/db_xref="GeneID:851535"
/translation="MFKVPVGLASRTRELMNSVTLNSLNNGKGFNMYLPGILRAFPKP
VPSAITSPAIPKYRGESFQFRKLSCISSNYCSTTHQFLSSLKSSTSRLVGKRAFHSSR
RAEIKFIFSSKSPKNGNKPFVKVYKVSPFFIIFATASIFTFILTSTIVVIPLIFHFFF
PLLIMFFFFKQFKKWQKNIFYKDVLTSLPKTKLKITLPTMRSLQLQPMVQSWKEISSR
MGIPNEFAKGLNVDLVKQEETRKQFLSFLQKRVLESFTKNELGIRSYFLGDSVEKWIK
ESYDLELDIDNCRSELRKFQTFIFSSVRYKLYLDSMKNLPLNPSKKLEGKKHIADVYV
IILDESFPAIMFNGGAYSKADFFKILQESETSNSSKTLNTIIAIKSVNTLLSKHFVIT
TNGDSGEFFSKYNISKINDKNTEYTLKE"
gene complement(405344..407206)
/gene="RTK1"
/locus_tag="YDL025C"
/db_xref="GeneID:851536"
mRNA complement(405344..407206)
/gene="RTK1"
/locus_tag="YDL025C"
/product="Rtk1p"
/transcript_id="NM_001180084.1"
/db_xref="GI:296143334"
/db_xref="GeneID:851536"
CDS complement(405344..407206)
/gene="RTK1"
/locus_tag="YDL025C"
/EC_number="2.7.11.1"
/note="Putative protein kinase, potentially phosphorylated
by Cdc28p; interacts with ribosome biogenesis factors,
Cka2, Gus1 and Arc1; protein abundance increases in
response to DNA replication stress"
/codon_start=1
/product="Rtk1p"
/protein_id="NP_010259.1"
/db_xref="GI:6320179"
/db_xref="SGD:S000002183"
/db_xref="GeneID:851536"
/translation="MVKETPLHSSSSTSLSSLFRPTKLKNLSAKIFNGGGNQSYSKTD
DVSRSSSRSSKKNTDSDQEDQIKYNKPNDRRSTIGKSPQGNGALSKESHVVASSTLTG
ISPTSAKKAPIDYSPSRPLPNNHNPVRTGHTVPHLPHSIHNPINYIHQGSKDAFHHPH
PVRSTAHSNISTVSSAKSDTPSSNLSYQAHMHPVEILQKQIEDKHFMDSQASTPGSVE
LQHNSSSGSDDTSSRKKKSLRLTRFFKKIHNDYHDNHHHHHHHNRGSTPTKPKLNLNT
NENIVESNGKALYETDNPVELLEKYGIPGRKLGEGASGSVSVVERTDGKLFACKMFRK
PHLNNEGTNQSQLANYSKKVTTEFCIGSTLHHENIVETLDMLTEGDTYLLVMEYAPYD
FFNLVMSNLMTQDEVNCYFKQLCHGVNYLHSMGLAHRDLKLDNCVVTKDGILKLIDFG
SAVVFQYPYEDTIVKSHGIVGSDPYLAPELLKQTSYDPRVADVWSIAIIFYCMVLKRF
PWKAPKKSFNSFRLFTEEPEDEDDIVRGPNKILRLLPRHSRTIIGRMLALEPKQRVLM
NDVVKDDWLVSVPSCEVDPTSGDLVEKPKNHKHHLVTEEELNELTKQHGNKDSN"
rep_origin 408075..408316
/note="ARS414;
Autonomously Replicating Sequence"
/db_xref="SGD:S000118433"
gene complement(408451..409857)
/gene="DIA3"
/locus_tag="YDL024C"
/db_xref="GeneID:851537"
mRNA complement(408451..409857)
/gene="DIA3"
/locus_tag="YDL024C"
/product="Dia3p"
/transcript_id="NM_001180083.1"
/db_xref="GI:296143335"
/db_xref="GeneID:851537"
CDS complement(408451..409857)
/gene="DIA3"
/locus_tag="YDL024C"
/EC_number="3.1.3.2"
/note="hypothetical protein, involved in invasive and
pseudohyphal growth"
/codon_start=1
/product="Dia3p"
/protein_id="NP_010260.1"
/db_xref="GI:6320180"
/db_xref="SGD:S000002182"
/db_xref="GeneID:851537"
/translation="MVKPVIFAICLGVLLSKALSIPLRSFADIELIGSQKSLFPFLGG
SAPYFSFPANYGIPTDIPEGCRLTQVQMIGRHGERYPTRSEAKDIFEVWYKISNYTGK
YEGSLSFLNNGYEFFIPDESLLEMETTLQNSIDVLNPYTGEMNAKRHAREFLAKYGKL
MENCTNFPIFTTNSKRIYDTAQYFAEALGDGFNISLQTLSENSSSGANTLAAKSSCPN
WNSNANNDILMSYSRDYLENISDRLNDENKGLNLSRKDAAALFSWCAFELNAKGYSNI
CDIFSAAELIHYSYETDLTSFYQNGPGYKLIKSIGANLFNATVKLIRQSAHLDQKVWL
SFTHDTDILNYLTTAGLIDDTRNLTTNHVPFRDHSYHRSWYIPQGARVYTEKFQCSND
SYVRYVVNDAVVPIESCSSGPGFSCEEGTFYEYAKDRLRGVSFYEDCDVSKVSKEKEL
TFYWDWNTTRYNASLVNQ"
gene complement(409808..410056)
/locus_tag="YDL022C-A"
/db_xref="GeneID:13393611"
mRNA complement(409808..410056)
/locus_tag="YDL022C-A"
/product="hypothetical protein"
/transcript_id="NM_001270741.1"
/db_xref="GI:398364786"
/db_xref="GeneID:13393611"
CDS complement(409808..410056)
/locus_tag="YDL022C-A"
/note="hypothetical protein; partially overlaps the
verified gene DIA3; identified by fungal homology and
RT-PCR; mRNA identified as translated by ribosome
profiling data"
/codon_start=1
/product="hypothetical protein"
/protein_id="NP_001257670.1"
/db_xref="GI:398364787"
/db_xref="SGD:S000028537"
/db_xref="GeneID:13393611"
/translation="MYYLVPKTTYGNLQCSSLAMTFHERGESGDVLSCACRLYLYIMP
LFFNTFLRQKYFQLCSNTPYRNNGEARYFCHLFRCSII"
gene 410379..410451
/locus_tag="tA(AGC)D"
/db_xref="GeneID:851538"
tRNA 410379..410451
/locus_tag="tA(AGC)D"
/product="tRNA-Ala"
/note="Alanine tRNA (tRNA-Ala), predicted by tRNAscan-SE
analysis; one of 11 nuclear tRNA genes containing the
tDNA-anticodon AGC (converted to IGC in the mature tRNA),
decodes GCU and GCC codons into alanine, one of 16 nuclear
tRNAs for alanine"
/db_xref="SGD:S000006510"
/db_xref="GeneID:851538"
gene 411825..413000
/gene="GPD1"
/locus_tag="YDL022W"
/gene_synonym="DAR1; HOR1; OSG1; OSR5"
/db_xref="GeneID:851539"
mRNA 411825..413000
/gene="GPD1"
/locus_tag="YDL022W"
/gene_synonym="DAR1; HOR1; OSG1; OSR5"
/product="glycerol-3-phosphate dehydrogenase (NAD(+))
GPD1"
/transcript_id="NM_001180081.1"
/db_xref="GI:296143336"
/db_xref="GeneID:851539"
CDS 411825..413000
/gene="GPD1"
/locus_tag="YDL022W"
/gene_synonym="DAR1; HOR1; OSG1; OSR5"
/note="NAD-dependent glycerol-3-phosphate dehydrogenase;
key enzyme of glycerol synthesis, essential for growth
under osmotic stress; expression regulated by
high-osmolarity glycerol response pathway; homolog of
Gpd2p; protein abundance increases in response to DNA
replication stress; constitutively inactivated via
phosphorylation by the protein kinases YPK1 and YPK2,
dephosphorylation increases catalytic activity"
/codon_start=1
/product="glycerol-3-phosphate dehydrogenase (NAD(+))
GPD1"
/protein_id="NP_010262.1"
/db_xref="GI:6320181"
/db_xref="SGD:S000002180"
/db_xref="GeneID:851539"
/translation="MSAAADRLNLTSGHLNAGRKRSSSSVSLKAAEKPFKVTVIGSGN
WGTTIAKVVAENCKGYPEVFAPIVQMWVFEEEINGEKLTEIINTRHQNVKYLPGITLP
DNLVANPDLIDSVKDVDIIVFNIPHQFLPRICSQLKGHVDSHVRAISCLKGFEVGAKG
VQLLSSYITEELGIQCGALSGANIATEVAQEHWSETTVAYHIPKDFRGEGKDVDHKVL
KALFHRPYFHVSVIEDVAGISICGALKNVVALGCGFVEGLGWGNNASAAIQRVGLGEI
IRFGQMFFPESREETYYQESAGVADLITTCAGGRNVKVARLMATSGKDAWECEKELLN
GQSAQGLITCKEVHEWLETCGSVEDFPLFEAVYQIVYNNYPMKNLPDMIEELDLHED"
gene 413953..414888
/gene="GPM2"
/locus_tag="YDL021W"
/db_xref="GeneID:851541"
mRNA 413953..414888
/gene="GPM2"
/locus_tag="YDL021W"
/product="phosphoglycerate mutase family protein GPM2"
/transcript_id="NM_001180080.1"
/db_xref="GI:296143337"
/db_xref="GeneID:851541"
CDS 413953..414888
/gene="GPM2"
/locus_tag="YDL021W"
/EC_number="5.4.2.1"
/note="Homolog of Gpm1p phosphoglycerate mutase, which
converts 3-phosphoglycerate to 2-phosphoglycerate in
glycolysis; may be non-functional derivative of a gene
duplication event"
/codon_start=1
/product="phosphoglycerate mutase family protein GPM2"
/protein_id="NP_010263.1"
/db_xref="GI:6320183"
/db_xref="SGD:S000002179"
/db_xref="GeneID:851541"
/translation="MTASTPSNVMTLFLLRHGQSELNHENIFCGWIDAKLTEKGKEQA
RHSAELIEQYCKANNLRLPQIGYTSRLIRTQQTIETMCEEFKLKPQLQVVYDFNKIKL
GDEFGSDDKDNMKIPILQTWRLNERHYGSWQGQRKPNVLKEYGKDKYMFIRRDYEGKP
PPVDLDREMIQQENEKGSSTGYEFKEPNRQIKYELECSNHDIVLPDSESLREVVYRLN
PFLQNVILKLANQYDESSCLIVGHGSSVRSLLKILEGISDDDIKNVDIPNGIPLVVEL
DKNNGLKFIRKFYLDPESAKINAEKVRNEGFIKNP"
gene complement(415113..416708)
/gene="RPN4"
/locus_tag="YDL020C"
/gene_synonym="SON1; UFD5"
/db_xref="GeneID:851542"
mRNA complement(415113..416708)
/gene="RPN4"
/locus_tag="YDL020C"
/gene_synonym="SON1; UFD5"
/product="Rpn4p"
/transcript_id="NM_001180079.3"
/db_xref="GI:398364804"
/db_xref="GeneID:851542"
CDS complement(415113..416708)
/gene="RPN4"
/locus_tag="YDL020C"
/gene_synonym="SON1; UFD5"
/note="Transcription factor that stimulates expression of
proteasome genes; Rpn4p levels are in turn regulated by
the 26S proteasome in a negative feedback control
mechanism; RPN4 is transcriptionally regulated by various
stress responses; relative distribution to the nucleus
increases upon DNA replication stress"
/codon_start=1
/product="Rpn4p"
/protein_id="NP_010264.3"
/db_xref="GI:398364805"
/db_xref="SGD:S000002178"
/db_xref="GeneID:851542"
/translation="MASTELSLKRTLTDILEDELYHTNPGHSQFTSHYQNYHPNASIT
PYKLVNKNKENNTFTWNHSLQHQNESSAASIPPQQTYHFPIFNKYADPTLTTTTSFTT
SEATANDRQINNVHLIPNEIKGASETPLQKTVNLKNIMKVSDPYVPTRNTFNYDVKIS
NDFFDNGDNLYGNDEEVLFYEDNYNPKMQWSLQDNSAAINNEDARAIFNNEFDSDDDD
ISDDEEDEIEENCLQQEQHQEEPLLSLDVTPISMFGSDQKTGRAKSSSHLFNEYSYVD
SNMDSISSVVSEDLLDERGHEKIEDEDEDNDLDEDDIYDISLLKNRRKQSFVLNKNTI
DFERFPSPSTSANVPSTATTGKRKPAKSSSNRSCVSNSNENGTLERIKKPTSAVVSSN
ASRRKLINYTKKHLSSHSSTNSNSKPSTASPSAHTSSSDGNNEIFTCQIMNLITNEPC
GAQFSRSYDLTRHQNTIHAKRKIVFRCSECIKILGSEGYQKTFSRLDALTRHIKSKHE
DLSLEQRQEVTKFAKANIGYVMG"
gene complement(417663..421514)
/gene="OSH2"
/locus_tag="YDL019C"
/db_xref="GeneID:851543"
mRNA complement(417663..421514)
/gene="OSH2"
/locus_tag="YDL019C"
/product="Osh2p"
/transcript_id="NM_001180078.1"
/db_xref="GI:296143339"
/db_xref="GeneID:851543"
CDS complement(417663..421514)
/gene="OSH2"
/locus_tag="YDL019C"
/note="Member of an oxysterol-binding protein family with
seven members in S. cerevisiae; family members have
overlapping, redundant functions in sterol metabolism and
collectively perform a function essential for viability"
/codon_start=1
/product="Osh2p"
/protein_id="NP_010265.1"
/db_xref="GI:6320185"
/db_xref="SGD:S000002177"
/db_xref="GeneID:851543"
/translation="MSREDLSIAEDLNQVSKPLLKVKLLEVLGQGDFKHLKALVDNEF
QPKDDPSVQQVLNLILHYAVQVAPILLIKEIVAHWVDQVGDEKSSSKSDDGIHLDLNY
QDENGNTPLHLAAAQSRSDVISFLLSQKSINDCVKNKAHQQPLDMCKDLNVAQMIQLK
RDDYFLETVHSLRAAMNKRDFSKLDSIWKNPRNLNLLDINGIDPETGTTLLYEYSQKK
DIEMCQWLLKHGAEATVKDGKGRSPLDLVKNIKLPAKPSNNVTPEIKLKNLLEKNLRE
QAIVHEDVASSKPPTYKGFLKKWTNFAHGYKLRWFILSGDGNLSYYKDQSHVDRPRGT
LKVSTCRLHIDSSEKLNFELLGGITGTTRWRLKGNHPIETTRWVNAIQSAIRFAKDKE
ILNKKKAVPPSLALKNKSPALISHSKTQGSLPEASQYYQHTLHKEVIQPSSVSLYRRP
SNNLSVVSSEIQLNDNLTESGKRFVSKMIENRLDGSKTPVGVHTGSALQRVRSSNTLK
SNRSMQSGSGVASPIDKVPNGANLSQSNTTTGSTASLSDNNYIDNFEGDEANSDDEEE
DLGINFDRDEEYIKAQYGPYKEKLDMYEQAISIELSSLIELIEQEEPSPEVWLTIKKS
LINTSTIFGKLKDLTYKRDKRLVDMVSKQGDVNNVWVQSVKELEMELSNKTERLASID
KERRGLKKILHKKLLESHATAGNKESLENDKEQESDTTASTLGQIAKFISATKEEDEA
SDADEFYDAAELVDEVTELTEAHPEISTAAAPKHAPPPVPNETDNDSQYVQDEKSKIE
SNVEKTSQKFEKQNNLVTEDEPKTDQSLKNFKAEDKESQVKEKTKEIASSVIGEKTIV
AVTTVQKRKEEYLLKEGSYLGYEDGIRKRLSMDKDDRPKISLWAVLKSMVGKDMTRMT
LPVTFNEPTSLLQRVAEDLEYSELLDQAATFEDSTLRTLYVAAFTASSYASTTKRVAK
PFNPLLGETFEYSRPDKQYRFFTEQVSHHPPISATWTESPRWDFWGESFVDTKFNGRS
FNVKHLGLWHIKLRPNDNEKEELYTWKKPNNTVIGILIGNPQVDNHGEVNVVNHTTGD
HCKLYFKARGWRSSGAYEITGEVYNKKKQKVWILGGHWNEAIFAKKVVKDGDLSLEKT
RTAASAGNGPTDDGTKFLIWKANDRPEEPFNLTPFAITLNAPQPHLLPWLPPTDTRLR
PDQRAMEDGRYDEAGDEKFRVEEKQRAARRKREENNLEYHPQWFVRDTHPITKAKYWR
YTGKYWVKRRDHDLKDCGDIF"
gene complement(422833..423510)
/gene="ERP3"
/locus_tag="YDL018C"
/db_xref="GeneID:851544"
mRNA complement(422833..423510)
/gene="ERP3"
/locus_tag="YDL018C"
/product="Erp3p"
/transcript_id="NM_001180077.1"
/db_xref="GI:296143340"
/db_xref="GeneID:851544"
CDS complement(422833..423510)
/gene="ERP3"
/locus_tag="YDL018C"
/note="Protein with similarity to Emp24p and Erv25p,
member of the p24 family involved in ER to Golgi
transport"
/codon_start=1
/product="Erp3p"
/protein_id="NP_010266.1"
/db_xref="GI:6320186"
/db_xref="SGD:S000002176"
/db_xref="GeneID:851544"
/translation="MSNLCVLFFQFFFLAQFFAEASPLTFELNKGRKECLYTLTPEID
CTISYYFAVQQGESNDFDVNYEIFAPDDKNKPIIERSGERQGEWSFIGQHKGEYAICF
YGGKAHDKIVDLDFKYNCERQDDIRNERRKARKAQRNLRDSKTDPLQDSVENSIDTIE
RQLHVLERNIQYYKSRNTRNHHTVCSTEHRIVMFSIYGILLIIGMSCAQIAILEFIFR
ESRKHNV"
gene 424209..425732
/gene="CDC7"
/locus_tag="YDL017W"
/gene_synonym="LSD6; SAS1"
/db_xref="GeneID:851545"
mRNA 424209..425732
/gene="CDC7"
/locus_tag="YDL017W"
/gene_synonym="LSD6; SAS1"
/product="Cdc7p"
/transcript_id="NM_001180076.3"
/db_xref="GI:398364828"
/db_xref="GeneID:851545"
CDS 424209..425732
/gene="CDC7"
/locus_tag="YDL017W"
/gene_synonym="LSD6; SAS1"
/EC_number="2.7.11.1"
/note="DDK (Dbf4-dependent kinase) catalytic subunit
required for origin firing and replication fork
progression in mitotic S phase through phosphorylation of
Mcm2-7p complexes and Cdc45p; kinase activity correlates
with cyclical DBF4 expression; required for pre-meiotic
DNA replication, meiotic DSB formation, recruitment of the
monopolin complex to kinetochores during meiosis I and as
a gene-specific regulator of the meiosis-specific
transcription factor Ndt80p"
/codon_start=1
/product="Cdc7p"
/protein_id="NP_010267.3"
/db_xref="GI:398364829"
/db_xref="SGD:S000002175"
/db_xref="GeneID:851545"
/translation="MTSKTKNIDDIPPEIKEEMIQLYHDLPGIENEYKLIDKIGEGTF
SSVYKAKDITGKITKKFASHFWNYGSNYVALKKIYVTSSPQRIYNELNLLYIMTGSSR
VAPLCDAKRVRDQVIAVLPYYPHEEFRTFYRDLPIKGIKKYIWELLRALKFVHSKGII
HRDIKPTNFLFNLELGRGVLVDFGLAEAQMDYKSMISSQNDYDNYANTNHDGGYSMRN
HEQFCPCIMRNQYSPNSHNQTPPMVTIQNGKVVHLNNVNGVDLTKGYPKNETRRIKRA
NRAGTRGFRAPEVLMKCGAQSTKIDIWSVGVILLSLLGRRFPMFQSLDDADSLLELCT
IFGWKELRKCAALHGLGFEASGLIWDKPNGYSNGLKEFVYDLLNKECTIGTFPEYSVA
FETFGFLQQELHDRMSIEPQLPDPKTNMDAVDAYELKKYQEEIWSDHYWCFQVLEQCF
EMDPQKRSSAEDLLKTPFFNELNENTYLLDGESTDEDDVVSSSEADLLDKDVLLISE"
gene complement(426002..426934)
/gene="TSC13"
/locus_tag="YDL015C"
/db_xref="GeneID:851547"
mRNA complement(426002..426934)
/gene="TSC13"
/locus_tag="YDL015C"
/product="trans-2-enoyl-CoA reductase (NADPH) TSC13"
/transcript_id="NM_001180074.1"
/db_xref="GI:296143342"
/db_xref="GeneID:851547"
CDS complement(426002..426934)
/gene="TSC13"
/locus_tag="YDL015C"
/EC_number="1.3.1.38"
/note="Enoyl reductase; catalyzes the last step in each
cycle of very long chain fatty acid elongation; localizes
to the ER, highly enriched in a structure marking
nuclear-vacuolar junctions; coimmunoprecipitates with
elongases Fen1p and Sur4p; protein increases in abundance
and relative distribution to ER foci increases upon DNA
replication stress"
/codon_start=1
/product="trans-2-enoyl-CoA reductase (NADPH) TSC13"
/protein_id="NP_010269.1"
/db_xref="GI:6320189"
/db_xref="SGD:S000002173"
/db_xref="GeneID:851547"
/translation="MPITIKSRSKGLRDTEIDLSKKPTLDDVLKKISANNHNISKYRI
RLTYKKESKQVPVISESFFQEEADDSMEFFIKDLGPQISWRLVFFCEYLGPVLVHSLF
YYLSTIPTVVDRWHSASSDYNPFLNRVAYFLILGHYGKRLFETLFVHQFSLATMPIFN
LFKNCFHYWVLSGLISFGYFGYGFPFGNAKLFKYYSYLKLDDLSTLIGLFVLSELWNF
YCHIKLRLWGDYQKKHGNAKIRVPLNQGIFNLFVAPNYTFEVWSWIWFTFVFKFNLFA
VLFLTVSTAQMYAWAQKKNKKYHTRRAFLIPFVF"
gene 427364..428347
/gene="NOP1"
/locus_tag="YDL014W"
/gene_synonym="LOT3"
/db_xref="GeneID:851548"
mRNA 427364..428347
/gene="NOP1"
/locus_tag="YDL014W"
/gene_synonym="LOT3"
/product="Nop1p"
/transcript_id="NM_001180073.1"
/db_xref="GI:296143343"
/db_xref="GeneID:851548"
CDS 427364..428347
/gene="NOP1"
/locus_tag="YDL014W"
/gene_synonym="LOT3"
/EC_number="2.1.1.-"
/note="Nucleolar protein, component of the small subunit
processome complex, which is required for processing of
pre-18S rRNA; has similarity to mammalian fibrillarin"
/codon_start=1
/product="Nop1p"
/protein_id="NP_010270.1"
/db_xref="GI:6320190"
/db_xref="SGD:S000002172"
/db_xref="GeneID:851548"
/translation="MSFRPGSRGGSRGGSRGGFGGRGGSRGGARGGSRGGFGGRGGSR
GGARGGSRGGFGGRGGSRGGARGGSRGGRGGAAGGARGGAKVVIEPHRHAGVYIARGK
EDLLVTKNMAPGESVYGEKRISVEEPSKEDGVPPTKVEYRVWNPFRSKLAAGIMGGLD
ELFIAPGKKVLYLGAASGTSVSHVSDVVGPEGVVYAVEFSHRPGRELISMAKKRPNII
PIIEDARHPQKYRMLIGMVDCVFADVAQPDQARIIALNSHMFLKDQGGVVISIKANCI
DSTVDAETVFAREVQKLREERIKPLEQLTLEPYERDHCIVVGRYMRSGLKK"
gene 429067..430926
/gene="SLX5"
/locus_tag="YDL013W"
/gene_synonym="HEX3; ULS2"
/db_xref="GeneID:851549"
mRNA 429067..430926
/gene="SLX5"
/locus_tag="YDL013W"
/gene_synonym="HEX3; ULS2"
/product="SUMO-targeted ubiquitin ligase complex subunit
SLX5"
/transcript_id="NM_001180072.3"
/db_xref="GI:398364838"
/db_xref="GeneID:851549"
CDS 429067..430926
/gene="SLX5"
/locus_tag="YDL013W"
/gene_synonym="HEX3; ULS2"
/note="Subunit of the Slx5-Slx8 SUMO-targeted ubiquitin
ligase (STUbL) complex, stimulated by SUMO-modified
substrates; contains a RING domain and two SIMs
(SUMO-interacting motifs); forms SUMO-dependent nuclear
foci, including DNA repair centers"
/codon_start=1
/product="SUMO-targeted ubiquitin ligase complex subunit
SLX5"
/protein_id="NP_010271.3"
/db_xref="GI:398364839"
/db_xref="SGD:S000002171"
/db_xref="GeneID:851549"
/translation="MHSDTNGRTKSNNSPSDNNPNETVILIDSDKEEDASIREANLPV
RLYPDRRVGRRRDALNRFVRSDSRSRNSQRTHITASSERPDFQANNDDITIIREVGRF
FGDDGPIDPSAHYVDLDQEPGSETLETPRTIQVDNTNGYLNDNGNNNESDDGLTIVEE
RTTRPRVTLNLPGGERLEVTATTTDIPIRRSFEFQEDLGASRRQLLRRSATRARNLFV
DRSDENDEDWTDDTHNLPEAIQRARRESRMRMSRRIAERQRRVQQQRVSSDENISTSI
RLQSIRERIQSYTPDIRSAFHRAESLHEFRSILQNVAPITLQECEEELMALFTEFRNQ
LLQNWAIDRVRNTQEEALRLHREALERQERTAGRVFHRGTLRESITNYLNFNGEDGFL
SRLWSGPALSDADEERHTQNIIDMIQEREERERDVVMKNLMNKTRAQQEEFEARAASL
PEGYSASFDTTPKMKLDITKNGKEETIIVTDDDLAKTLEDIPVCCLCGAELGVGIPDD
FTGISQKDRGVSFEGLVSKYKFHCPYQTLARPSMLDRDLSKRTFIASCGHAFCGRCFA
RIDNAKKKSKMPKKKLAQLKGSAHPDNYGPKLCPADSCKKLIRSRGRLKEVYF"
gene complement(431108..431517)
/locus_tag="YDL012C"
/db_xref="GeneID:851550"
mRNA complement(join(431108..431386,431473..431517))
/locus_tag="YDL012C"
/product="hypothetical protein"
/transcript_id="NM_001180071.1"
/db_xref="GI:296143345"
/db_xref="GeneID:851550"
CDS complement(join(431108..431386,431473..431517))
/locus_tag="YDL012C"
/note="Tail-anchored plasma membrane protein containing a
conserved CYSTM module, possibly involved in response to
stress; may contribute to non-homologous end-joining
(NHEJ) based on ydl012c htz1 double null phenotype"
/codon_start=1
/product="hypothetical protein"
/protein_id="NP_010272.1"
/db_xref="GI:6320192"
/db_xref="SGD:S000002170"
/db_xref="GeneID:851550"
/translation="MSAQDYYGNSASKQSYSRPSAPPPGYETASRGYAPSQSQQNYYP
PQQQQQQYQQQPQYYQQQQPQYYQQHPQQPIYVQQQPASSGNEDCLAGCLAGLCLCCT
LDMLF"
gene 432330..433025
/gene="GRX6"
/locus_tag="YDL010W"
/db_xref="GeneID:851551"
mRNA 432330..433025
/gene="GRX6"
/locus_tag="YDL010W"
/product="glutathione-disulfide reductase GRX6"
/transcript_id="NM_001180069.1"
/db_xref="GI:296143346"
/db_xref="GeneID:851551"
CDS 432330..433025
/gene="GRX6"
/locus_tag="YDL010W"
/note="Cis-golgi localized monothiol glutaredoxin that
binds an iron-sulfur cluster; more similar in activity to
dithiol than other monothiol glutaredoxins; involved in
the oxidative stress response; functional overlap with
GRX7"
/codon_start=1
/product="glutathione-disulfide reductase GRX6"
/protein_id="NP_010274.1"
/db_xref="GI:6320193"
/db_xref="SGD:S000002168"
/db_xref="GeneID:851551"
/translation="MIPSNKRNARILSITTLLLLLVFFVAQNANFLTVEIKEETSKAF
STNMDNMAGGSSREYAAMPTSTTNKGSSEVDEEINEIKQKVGLQQPIASVDDSLSAIK
NDKGSRITKAFNVQKEYSLILDLSPIIIFSKSTCSYSKGMKELLENEYQFIPNYYIIE
LDKHGHGEELQEYIKLVTGRGTVPNLLVNGVSRGGNEEIKKLHTQGKLLESLQVWSDG
KFSVEQREKPSNN"
gene complement(432925..433248)
/locus_tag="YDL009C"
/db_xref="GeneID:851553"
mRNA complement(432925..433248)
/locus_tag="YDL009C"
/product="hypothetical protein"
/transcript_id="NM_001270742.1"
/db_xref="GI:398364862"
/db_xref="GeneID:851553"
CDS complement(432925..433248)
/locus_tag="YDL009C"
/note="hypothetical protein; mRNA identified as translated
by ribosome profiling data; partially overlaps the
verified ORF YDL010W; YDL009C is not an essential gene"
/codon_start=1
/product="hypothetical protein"
/protein_id="NP_001257671.1"
/db_xref="GI:398364863"
/db_xref="SGD:S000002167"
/db_xref="GeneID:851553"
/translation="MKALSVLCFHNPFKRCLGQKSFFVGDSFFIPTPKRLVLGKLRLS
NYTAFHDLIIHDLFIYIFILNFFFFPFCNNFNYWKVFHVAQPRIYHHSRLVMILKVSL
ECAVS"
gene 433497..433994
/gene="APC11"
/locus_tag="YDL008W"
/db_xref="GeneID:851554"
mRNA 433497..433994
/gene="APC11"
/locus_tag="YDL008W"
/product="anaphase promoting complex subunit 11"
/transcript_id="NM_001180067.3"
/db_xref="GI:398364868"
/db_xref="GeneID:851554"
CDS 433497..433994
/gene="APC11"
/locus_tag="YDL008W"
/EC_number="6.3.2.-"
/note="Catalytic core subunit of the Anaphase-Promoting
Complex/Cyclosome (APC/C), which is a ubiquitin-protein
ligase required for degradation of anaphase inhibitors,
including mitotic cyclins, during the metaphase/anaphase
transition; contains a RING-H2 domain that is required for
activity"
/codon_start=1
/product="anaphase promoting complex subunit 11"
/protein_id="NP_010276.3"
/db_xref="GI:398364869"
/db_xref="SGD:S000002166"
/db_xref="GeneID:851554"
/translation="MKVKINEVHSVFAWSWHIPSTSDEDAANNDPIGNDEDEDVCGIC
RASYNGTCPSCKFPGDQCPLVIGLCHHNFHDHCIYRWLDTPTSKGLCPMCRQTFQLQK
GLAINDAHVQKFVEIVSRRREEMIEEGVAEEFVDFDEPIRQNTDNPIGRQQVDTILDE
DFLLR"
gene complement(434264..434336)
/locus_tag="tT(AGU)D"
/db_xref="GeneID:851555"
tRNA complement(434264..434336)
/locus_tag="tT(AGU)D"
/product="tRNA-Thr"
/note="Threonine tRNA (tRNA-Thr), predicted by tRNAscan-SE
analysis"
/db_xref="SGD:S000006739"
/db_xref="GeneID:851555"
LTR complement(434423..434739)
/note="Ty1 LTR"
/db_xref="SGD:S000006842"
rep_origin 434784..435989
/note="ARS415;
Putative replication origin, identified in multiple array
studies, not yet confirmed by plasmid-based assay"
/db_xref="SGD:S000130173"
gene complement(436567..436824)
/locus_tag="YDL007C-A"
/db_xref="GeneID:3799969"
mRNA complement(436567..436824)
/locus_tag="YDL007C-A"
/product="hypothetical protein"
/transcript_id="NM_001184682.1"
/db_xref="GI:296143348"
/db_xref="GeneID:3799969"
CDS complement(436567..436824)
/locus_tag="YDL007C-A"
/codon_start=1
/product="hypothetical protein"
/protein_id="NP_001032574.1"
/db_xref="GI:82795244"
/db_xref="SGD:S000113557"
/db_xref="GeneID:3799969"
/translation="MFLPIIFHTILTLLNFGKYYCLPIQEDDDKSGKEIEQILDNNIE
SLGLLLNSMSLSSNFTTGDPELDSLFQDDLIPELYSVLDGF"
LTR 437149..437518
/note="Ty4 LTR"
/db_xref="SGD:S000006843"
gene 437772..437853
/locus_tag="tS(AGA)D1"
/db_xref="GeneID:851556"
tRNA 437772..437853
/locus_tag="tS(AGA)D1"
/product="tRNA-Ser"
/note="Serine tRNA (tRNA-Ser), predicted by tRNAscan-SE
analysis"
/db_xref="SGD:S000006721"
/db_xref="GeneID:851556"
gene 438047..439360
/gene="RPT2"
/locus_tag="YDL007W"
/gene_synonym="YHS4; YTA5"
/db_xref="GeneID:851557"
mRNA 438047..439360
/gene="RPT2"
/locus_tag="YDL007W"
/gene_synonym="YHS4; YTA5"
/product="proteasome regulatory particle base subunit
RPT2"
/transcript_id="NM_001180066.1"
/db_xref="GI:296143349"
/db_xref="GeneID:851557"
CDS 438047..439360
/gene="RPT2"
/locus_tag="YDL007W"
/gene_synonym="YHS4; YTA5"
/note="One of six ATPases of the 19S regulatory particle
of the 26S proteasome involved in the degradation of
ubiquitinated substrates; required for normal peptide
hydrolysis by the core 20S particle"
/codon_start=1
/product="proteasome regulatory particle base subunit
RPT2"
/protein_id="NP_010277.1"
/db_xref="GI:6320197"
/db_xref="SGD:S000002165"
/db_xref="GeneID:851557"
/translation="MGQGVSSGQDKKKKKGSNQKPKYEPPVQSKFGRKKRKGGPATAE
KLPNIYPSTRCKLKLLRMERIKDHLLLEEEFVSNSEILKPFEKKQEEEKKQLEEIRGN
PLSIGTLEEIIDDDHAIVTSPTMPDYYVSILSFVDKELLEPGCSVLLHHKTMSIVGVL
QDDADPMVSVMKMDKSPTESYSDIGGLESQIQEIKESVELPLTHPELYEEMGIKPPKG
VILYGAPGTGKTLLAKAVANQTSATFLRIVGSELIQKYLGDGPRLCRQIFKVAGENAP
SIVFIDEIDAIGTKRYDSNSGGEREIQRTMLELLNQLDGFDDRGDVKVIMATNKIETL
DPALIRPGRIDRKILFENPDLSTKKKILGIHTSKMNLSEDVNLETLVTTKDDLSGADI
QAMCTEAGLLALRERRMQVTAEDFKQAKERVMKNKVEENLEGLYL"
gene 439909..440754
/gene="PTC1"
/locus_tag="YDL006W"
/gene_synonym="CWH47; KCS2; TPD1"
/db_xref="GeneID:851558"
mRNA 439909..440754
/gene="PTC1"
/locus_tag="YDL006W"
/gene_synonym="CWH47; KCS2; TPD1"
/product="Ptc1p"
/transcript_id="NM_001180065.3"
/db_xref="GI:398364892"
/db_xref="GeneID:851558"
CDS 439909..440754
/gene="PTC1"
/locus_tag="YDL006W"
/gene_synonym="CWH47; KCS2; TPD1"
/EC_number="3.1.3.16"
/note="Type 2C protein phosphatase (PP2C);
dephosphorylates Hog1p, inactivating osmosensing MAPK
cascade; involved in Fus3p activation during pheromone
response; deletion affects precursor tRNA splicing,
mitochondrial inheritance, and sporulation"
/codon_start=1
/product="Ptc1p"
/protein_id="NP_010278.3"
/db_xref="GI:398364893"
/db_xref="SGD:S000002164"
/db_xref="GeneID:851558"
/translation="MSNHSEILERPETPYDITYRVGVAENKNSKFRRTMEDVHTYVKN
FASRLDWGYFAVFDGHAGIQASKWCGKHLHTIIEQNILADETRDVRDVLNDSFLAIDE
EINTKLVGNSGCTAAVCVLRWELPDSVSDDSMDLAQHQRKLYTANVGDSRIVLFRNGN
SIRLTYDHKASDTLEMQRVEQAGGLIMKSRVNGMLAVTRSLGDKFFDSLVVGSPFTTS
VEITSEDKFLILACDGLWDVIDDQDACELIKDITEPNEAAKVLVRYALENGTTDNVTV
MVVFL"
gene complement(441014..442309)
/gene="MED2"
/locus_tag="YDL005C"
/db_xref="GeneID:851559"
mRNA complement(441014..442309)
/gene="MED2"
/locus_tag="YDL005C"
/product="Med2p"
/transcript_id="NM_001180064.3"
/db_xref="GI:398364900"
/db_xref="GeneID:851559"
CDS complement(441014..442309)
/gene="MED2"
/locus_tag="YDL005C"
/note="Subunit of the RNA polymerase II mediator complex;
associates with core polymerase subunits to form the RNA
polymerase II holoenzyme; essential for transcriptional
regulation"
/codon_start=1
/product="Med2p"
/protein_id="NP_010279.3"
/db_xref="GI:398364901"
/db_xref="SGD:S000002163"
/db_xref="GeneID:851559"
/translation="MVVQNSPVSSVHTANFSERGSNTRTMTYKNKLTVCFDDILKVGA
EMMMQQQLKNVQLDSYLVNGFSQSQQKLLKEKVKLFHGILDDLETSLSQSSSYLETLT
ALGKEKEKEREEAEKKRAEQENMRKVREQEELKKRQELEEASQQQQLQQNSKEKNGLG
LNFSTTAPANTTDANGSKENYQELGSLQSSSQTQLENANAANNGAAFSPLTTTRIQSQ
QAQPSDVMFNDLNSMDISMFSGLDSTGFDSTAFNATVDETKGFDDNDSGNNYNDINIS
SIENNINNNINSTKNGKDNNNESNKNNNGDEKNKNNNEDNENNNNSSEKNNNNNNNNN
NNNDDNGNNNNNNSGNDNNNTTNNDSNNKNNSITTGNDNENIVNNDLPTTVVSNPGDN
PPPADNGEEYLTLNDFNDLNIDWSTTGDNGELDLSGFNI"
gene 443029..443511
/gene="ATP16"
/locus_tag="YDL004W"
/db_xref="GeneID:851560"
mRNA 443029..443511
/gene="ATP16"
/locus_tag="YDL004W"
/product="F1F0 ATP synthase subunit delta"
/transcript_id="NM_001180063.1"
/db_xref="GI:296143352"
/db_xref="GeneID:851560"
CDS 443029..443511
/gene="ATP16"
/locus_tag="YDL004W"
/EC_number="3.6.3.14"
/note="Delta subunit of the central stalk of mitochondrial
F1F0 ATP synthase, which is a large, evolutionarily
conserved enzyme complex required for ATP synthesis;
phosphorylated"
/codon_start=1
/product="F1F0 ATP synthase subunit delta"
/protein_id="NP_010280.1"
/db_xref="GI:6320200"
/db_xref="SGD:S000002162"
/db_xref="GeneID:851560"
/translation="MLRSIIGKSASRSLNFVAKRSYAEAAAASSGLKLQFALPHETLY
SGSEVTQVNLPAKSGRIGVLANHVPTVEQLLPGVVEVMEGSNSKKFFISGGFATVQPD
SQLCVTAIEAFPLESFSQENIKNLLAEAKKNVSSSDAREAAEAAIQVEVLENLQSVLK
"
gene 444683..446383
/gene="MCD1"
/locus_tag="YDL003W"
/gene_synonym="PDS3; RHC21; SCC1"
/db_xref="GeneID:851561"
mRNA 444683..446383
/gene="MCD1"
/locus_tag="YDL003W"
/gene_synonym="PDS3; RHC21; SCC1"
/product="Mcd1p"
/transcript_id="NM_001180062.1"
/db_xref="GI:296143353"
/db_xref="GeneID:851561"
CDS 444683..446383
/gene="MCD1"
/locus_tag="YDL003W"
/gene_synonym="PDS3; RHC21; SCC1"
/note="Essential alpha-kleisin subunit of the cohesin
complex; required for sister chromatid cohesion in mitosis
and meiosis; apoptosis induces cleavage and translocation
of a C-terminal fragment to mitochondria; expression peaks
in S phase"
/codon_start=1
/product="Mcd1p"
/protein_id="NP_010281.1"
/db_xref="GI:6320201"
/db_xref="SGD:S000002161"
/db_xref="GeneID:851561"
/translation="MVTENPQRLTVLRLATNKGPLAQIWLASNMSNIPRGSVIQTHIA
ESAKEIAKASGCDDESGDNEYITLRTSGELLQGIVRVYSKQATFLLTDIKDTLTKISM
LFKTSQKMTSTVNRLNTVTRVHQLMLEDAVTEREVLVTPGLEFLDDTTIPVGLMAQEN
SMERKVQGAAPWDTSLEVGRRFSPDEDFEHNNLSSMNLDFDIEEGPITSKSWEEGTRQ
SSRNFDTHENYIQDDDFPLDDAGTIGWDLGITEKNDQNNDDDDNSVEQGRRLGESIMS
EEPTDFGFDLDIEKEAPAGNIDTITDAMTESQPKQTGTRRNSKLLNTKSIQIDEETEN
SESIASSNTYKEERSNNLLTPQPTNFTTKRLWSEITESMSYLPDPILKNFLSYESLKK
RKIHNGREGSIEEPELNVSLNLTDDVISNAGTNDNSFNELTDNMSDFVPIDAGLNEAP
FPEENIIDAKTRNEQTTIQTEKVRPTPGEVASKAIVQMAKILRKELSEEKEVIFTDVL
KSQANTEPENITKREASRGFFDILSLATEGCIGLSQTEAFGNIKIDAKPALFERFINA
"
gene complement(446967..447578)
/gene="NHP10"
/locus_tag="YDL002C"
/gene_synonym="HMO2"
/db_xref="GeneID:851562"
mRNA complement(446967..447578)
/gene="NHP10"
/locus_tag="YDL002C"
/gene_synonym="HMO2"
/product="Nhp10p"
/transcript_id="NM_001180061.3"
/db_xref="GI:398364916"
/db_xref="GeneID:851562"
CDS complement(446967..447578)
/gene="NHP10"
/locus_tag="YDL002C"
/gene_synonym="HMO2"
/note="Protein related to mammalian high mobility group
proteins; preferentially binds DNA ends, protecting them
from exonucleatic cleavage; likely component of the
chromatin-remodeling complex INO80 complex; proposed to be
involved in DNA repair"
/codon_start=1
/product="Nhp10p"
/protein_id="NP_010282.3"
/db_xref="GI:398364917"
/db_xref="SGD:S000002160"
/db_xref="GeneID:851562"
/translation="MSVEEKKRRLEELKDQNVVLGLAIQRSRLSVKRLKLEYGVLLER
LESRIELDPELNCEDPLPTLASFKQELLTKPFRKSKTKRHKVKERDPNMPKRPTNAYL
LYCEMNKERIRQNGSLDVTRDLAEGWKNLNEQDRKPYYKLYSEDRERYQMEMEIYNKK
ISNIDADDDKEENEQKIKNNEEGSSTKVADSKGGEDGSLVSSN"
gene 447984..449276
/gene="RMD1"
/locus_tag="YDL001W"
/db_xref="GeneID:851563"
mRNA 447984..449276
/gene="RMD1"
/locus_tag="YDL001W"
/product="Rmd1p"
/transcript_id="NM_001180060.3"
/db_xref="GI:398364922"
/db_xref="GeneID:851563"
CDS 447984..449276
/gene="RMD1"
/locus_tag="YDL001W"
/note="Cytoplasmic protein required for sporulation"
/codon_start=1
/product="Rmd1p"
/protein_id="NP_010283.3"
/db_xref="GI:398364923"
/db_xref="SGD:S000002159"
/db_xref="GeneID:851563"
/translation="MVDSNDDQPERHALLHNDIQTSNNSRPSLVQKKYLPTPQDTRKS
RASYTGSAMINPTSKQSRTGSGAQRTSRTAQKLKLLPEEPFQRDSERLTDLKNQEVYS
QVNRIKDKPARRDAEKLGKAHRHLLPRSTAYCTASSYNMKELVRWLKDCRKLHHTHPK
LFDECLYTPFIYNDWRGDKRFEDEDVIRLDDEGGEIIVSDKHPDLFIFEYGVVVMWGF
TEREEKAFLNDIEKFEKEKLAEEDIQVEEFNYYVTKSYQPRIYNDFITLRDGSNYMVK
LSISHAIAQSVKISLFEELVDNTIEDTQDIPQEIAYSGKVSMSKEDIMKSIGELFILR
ININLHGSVLDSPEIMWSEPQLEPIYQATRGYLEINQRVSLLNQRLEVISDLLQMLKE
QLGHSHEEYLEFIVILLVGVEVLISVINIVVDMLASQH"
centromere 449711..449821
/note="CEN4; Chromosome IV centromere"
/db_xref="SGD:S000006466"
centromere 449711..449720
/note="CEN4_CDEI of CEN4"
centromere 449721..449796
/note="CEN4_CDEII of CEN4"
centromere 449797..449821
/note="CEN4_CDEIII of CEN4"
gene complement(450220..452475)
/gene="NTH1"
/locus_tag="YDR001C"
/db_xref="GeneID:851564"
mRNA complement(450220..452475)
/gene="NTH1"
/locus_tag="YDR001C"
/product="alpha,alpha-trehalase NTH1"
/transcript_id="NM_001180309.1"
/db_xref="GI:296143356"
/db_xref="GeneID:851564"
CDS complement(450220..452475)
/gene="NTH1"
/locus_tag="YDR001C"
/EC_number="3.2.1.28"
/note="Neutral trehalase, degrades trehalose; required for
thermotolerance and may mediate resistance to other
cellular stresses; may be phosphorylated by Cdc28p"
/codon_start=1
/product="alpha,alpha-trehalase NTH1"
/protein_id="NP_010284.1"
/db_xref="GI:6320204"
/db_xref="SGD:S000002408"
/db_xref="GeneID:851564"
/translation="MSQVNTSQGPVAQGRQRRLSSLSEFNDPFSNAEVYYGPPTDPRK
QKQAKPAKINRTRTMSVFDNVSPFKKTGFGKLQQTRRGSEDDTYSSSQGNRRFFIEDV
DKTLNELLAAEDTDKNYQITIEDTGPKVLKVGTANSYGYKHINIRGTYMLSNLLQELT
IAKSFGRHQIFLDEARINENPVNRLSRLINTQFWNSLTRRVDLNNVGEIAKDTKIDTP
GAKNPRIYVPYDCPEQYEFYVQASQMHPSLKLEVEYLPKKITAEYVKSVNDTPGLLAL
AMEEHFNPSTGEKTLIGYPYAVPGGRFNELYGWDSYMMALGLLEANKTDVARGMVEHF
IFEINHYGKILNANRSYYLCRSQPPFLTEMALVVFKKLGGRSNPDAVDLLKRAFQASI
KEYKTVWTASPRLDPETGLSRYHPNGLGIPPETESDHFDTVLLPYASKHGVTLDEFKQ
LYNDGKIKEPKLDEFFLHDRGVRESGHDTTYRFEGVCAYLATIDLNSLLYKYEIDIAD
FIKEFCDDKYEDPLDHSITTSAMWKEMAKIRQEKITKYMWDDESGFFFDYNTKIKHRT
SYESATTFWALWAGLATKEQAQKMVEKALPKLEMLGGLAACTERSRGPISISRPIRQW
DYPFGWAPHQILAWEGLRSYGYLTVTNRLAYRWLFMMTKAFVDYNGIVVEKYDVTRGT
DPHRVEAEYGNQGADFKGAATEGFGWVNASYILGLKYMNSHARRALGACIPPISFFSS
LRPQERNLYGL"
gene 453045..453650
/gene="YRB1"
/locus_tag="YDR002W"
/gene_synonym="CST20; HTN1; SFO1"
/db_xref="GeneID:851565"
mRNA 453045..453650
/gene="YRB1"
/locus_tag="YDR002W"
/gene_synonym="CST20; HTN1; SFO1"
/product="Yrb1p"
/transcript_id="NM_001180310.1"
/db_xref="GI:296143357"
/db_xref="GeneID:851565"
CDS 453045..453650
/gene="YRB1"
/locus_tag="YDR002W"
/gene_synonym="CST20; HTN1; SFO1"
/note="Ran GTPase binding protein; involved in nuclear
protein import and RNA export, ubiquitin-mediated protein
degradation during the cell cycle; shuttles between the
nucleus and cytoplasm; is essential; homolog of human
RanBP1"
/codon_start=1
/product="Yrb1p"
/protein_id="NP_010285.1"
/db_xref="GI:6320205"
/db_xref="SGD:S000002409"
/db_xref="GeneID:851565"
/translation="MSSEDKKPVVDKKEEAAPKPPSSAVFSMFGGKKAEKPETKKDEE
DTKEETKKEGDDAPESPDIHFEPVVHLEKVDVKTMEEDEEVLYKVRAKLFRFDADAKE
WKERGTGDCKFLKNKKTNKVRILMRRDKTLKICANHIIAPEYTLKPNVGSDRSWVYAC
TADIAEGEAEAFTFAIRFGSKENADKFKEEFEKAQEINKKA"
gene 454122..454754
/gene="RCR2"
/locus_tag="YDR003W"
/gene_synonym="SSH5"
/db_xref="GeneID:851566"
mRNA 454122..454754
/gene="RCR2"
/locus_tag="YDR003W"
/gene_synonym="SSH5"
/product="Rcr2p"
/transcript_id="NM_001180311.3"
/db_xref="GI:398364940"
/db_xref="GeneID:851566"
CDS 454122..454754
/gene="RCR2"
/locus_tag="YDR003W"
/gene_synonym="SSH5"
/note="Vacuolar protein that presumably functions within
the endosomal-vacuolar trafficking pathway, affecting
events that determine whether plasma membrane proteins are
degraded or routed to the plasma membrane; similar to
Rcr1p"
/codon_start=1
/product="Rcr2p"
/protein_id="NP_010286.3"
/db_xref="GI:398364941"
/db_xref="SGD:S000002410"
/db_xref="GeneID:851566"
/translation="MILREQIDFLIHKRQDDNNNNGEAITDDDPFSSSSWRWGRWIFF
IFFIVALLILLFSTAKVNRRRRIMGQAPIRGTAWLTPPTYRQSERDYNGTQRCVEDYV
PEYTETANENDLGFYDERGEFHPNGKTEYLAPPPLSEEQASSTDKDLQRPVAAVVRIP
SESEFDFNLLRPTMNNFVNGQSNRNEQHSPTVESSSFDVNNAPARAKVSK"
gene 454782..454904
/locus_tag="YDR003W-A"
/db_xref="GeneID:1466432"
mRNA 454782..454904
/locus_tag="YDR003W-A"
/product="hypothetical protein"
/transcript_id="NM_001184646.3"
/db_xref="GI:398364946"
/db_xref="GeneID:1466432"
CDS 454782..454904
/locus_tag="YDR003W-A"
/note="hypothetical protein; identified by expression
profiling and mass spectrometry"
/codon_start=1
/product="hypothetical protein"
/protein_id="NP_878061.3"
/db_xref="GI:398364947"
/db_xref="SGD:S000028819"
/db_xref="GeneID:1466432"
/translation="MTCGIENSYKSAEKKKKYRSFRFFESRDYSELCIIVGTYY"
gene 455201..456583
/gene="RAD57"
/locus_tag="YDR004W"
/db_xref="GeneID:851567"
mRNA 455201..456583
/gene="RAD57"
/locus_tag="YDR004W"
/product="Rad57p"
/transcript_id="NM_001180312.1"
/db_xref="GI:296143360"
/db_xref="GeneID:851567"
CDS 455201..456583
/gene="RAD57"
/locus_tag="YDR004W"
/note="Protein that stimulates strand exchange by
stabilizing the binding of Rad51p to single-stranded DNA;
involved in the recombinational repair of double-strand
breaks in DNA during vegetative growth and meiosis; forms
heterodimer with Rad55p"
/codon_start=1
/product="Rad57p"
/protein_id="NP_010287.1"
/db_xref="GI:6320207"
/db_xref="SGD:S000002411"
/db_xref="GeneID:851567"
/translation="MPRALSIKFDNTYMDLYDELPESKLLYDEEFSYLLDAVRQNGVC
VVDFLTLTPKELARLIQRSINEVFRFQQLLVHEYNEKYLEICEKNSISPDNGPECFTT
ADVAMDELLGGGIFTHGITEIFGESSTGKSQLLMQLALSVQLSEPAGGLGGKCVYITT
EGDLPTQRLESMLSSRPAYEKLGITQSNIFTVSCNDLINQEHIINVQLPILLERSKGS
IKLVIIDSISHHLRVELQNKSFRESQENKNYLDRMAEKLQILAHDYSLSVVVANQVGD
KPLANSPVAHRTYVTDYDYQLGWLVGWKNSTILYRQMNSLLGASSNNDEILSDDEDYM
LIERVMSTVNDRNYDFFSKKKPPIIENKTVERNSSSPISRQSKKRKFDYRVPNLGLTW
SNHVSTRILLQKSFKASTIIQRGEAHLYKGGDSASFWQVKRTMKVVYSTFAKPGQIAY
QITKRGIETA"
gene complement(456836..458103)
/gene="MAF1"
/locus_tag="YDR005C"
/db_xref="GeneID:851568"
mRNA complement(join(456836..458017,458098..458103))
/gene="MAF1"
/locus_tag="YDR005C"
/product="Maf1p"
/transcript_id="NM_001180313.1"
/db_xref="GI:296143361"
/db_xref="GeneID:851568"
CDS complement(join(456836..458017,458098..458103))
/gene="MAF1"
/locus_tag="YDR005C"
/note="Highly conserved negative regulator of RNA
polymerase III; binds to the N-terminal domain of the
Rpc160p subunit of Pol III to prevent closed-complex
formation; localization and activity are regulated by
phosphorylation, mediated by TORC1, protein kinase A, and
Sch9p; localizes to cytoplasm during vegetative growth and
translocates to the nucleus and nucleolus under stress
conditions"
/codon_start=1
/product="Maf1p"
/protein_id="NP_010288.1"
/db_xref="GI:6320208"
/db_xref="SGD:S000002412"
/db_xref="GeneID:851568"
/translation="MKFIDELDIERVNQTLNFETNDCKIVGSCDIFTTKAVASDRKLY
KTIDQHLDTILQENENYNATLQQQLAAPETNQSPCSSPFYSNRRDSNSFWEQKRRISF
SEYNSNNNTNNSNGNSSNNNNYSGPNGSSPATFPKSAKLNDQNLKELVSNYDSGSMSS
SSLDSSSKNDERIRRRSSSSISSFKSGKSSNNNYSSGTATNNVNKRRKSSINERPSNL
SLGPFGPINEPSSRKIFAYLIAILNASYPDHDFSSVEPTDFVKTSLKTFISKFENTLY
SLGRQPEEWVWEVINSHMTLSDCVLFQYSPSNSFLEDEPGYLWNLIGFLYNRKRKRVA
YLYLICSRLNSSTGEVEDALAKKPQGKLIIDDGSNEYEGEYDFTYDENVIDDKSDQEE
SLQ"
gene complement(458542..461247)
/gene="SOK1"
/locus_tag="YDR006C"
/db_xref="GeneID:851569"
mRNA complement(458542..461247)
/gene="SOK1"
/locus_tag="YDR006C"
/product="Sok1p"
/transcript_id="NM_001180314.3"
/db_xref="GI:398364966"
/db_xref="GeneID:851569"
CDS complement(458542..461247)
/gene="SOK1"
/locus_tag="YDR006C"
/note="Protein whose overexpression suppresses the growth
defect of mutants lacking protein kinase A activity;
involved in cAMP-mediated signaling; localized to the
nucleus; similar to the mouse testis-specific protein
PBS13"
/codon_start=1
/product="Sok1p"
/protein_id="NP_010289.3"
/db_xref="GI:398364967"
/db_xref="SGD:S000002413"
/db_xref="GeneID:851569"
/translation="MDQPRTHSGPTTASNPAPSSTNSSSAPSATNSKQERSSSSLSKP
SSVVPSKDSPDGDAIAKTQAAALKNDMKSGDTSTLDGSSQNIIPNRASMQKYIDQSSD
LLSRSSGVITPSMSLNASTNATNNDSSGNSANSSDLKIPIDRDNTIFKTFDTKTGQFL
KNDDNEEEIRRNNKVDSIPPKNIYTNINNPSPSPPPSSKQPPSASAPQLPPATEPHKE
QAAQQQPPGNASNFLRIFSNKKMRSHSVPTILHSSLRKLSSHNQYYRNQNILLNHPTP
SGISKKKFSRNHHQPYLHSNNPLSSNPLSLKRAIFLNQQISGNASTNANNDNINNSTA
TSMTNQSFLSSSNFDLTLEDRINYIKATPTPVPFPPINLQGLKEIDLQEILKNPQLRH
DIIFDPLLQFRPNLDGERGNKKRQLANIYWNDVQNEIYVYSKRPEIFQYNRSRLVPLF
DTLRDVLLTIVPQKESPMINNVLDTELNIQELLKGSLIMSNLSGWLADLFKHHCAPMR
DPWVDKMSNKFKEAERDSSLTRLIEGLRLVFQILETMKLDIANHQIRILRPALLSNAV
EFEKQYFNTLIASKRVNLNTSLLWFDKKFNENVTAGLVRNPSSITIPDVYNICIRSII
NLLSCRKMVREYPTPLSFDHARLILLRADIRQIVCILVCRLLFQQLVANDPSMDKATK
EYVIHTYSTKRLKNEIISIITDEHGNCRWTKNTMSIAVHLCKVIDDLHREYDNNGSCE
QARRPQLPSLDNSKITFAKSWLSKQTQPLSEVYGVLENRVFKSLEDAIFNRSECTIDG
RVKQDFVYLYNTNNGNVGSTNTLSTTTDTASVKISPSLMSPSKTSTTTPTGNAIASRG
LFAATELEEFENVYRHLYALINLHWSVFGPHYIEMLGDKVNKKGI"
STS 461739..461835
/standard_name="D17S1252"
/db_xref="UniSTS:149865"
gene 461842..462516
/gene="TRP1"
/locus_tag="YDR007W"
/db_xref="GeneID:851570"
mRNA 461842..462516
/gene="TRP1"
/locus_tag="YDR007W"
/product="phosphoribosylanthranilate isomerase TRP1"
/transcript_id="NM_001180315.3"
/db_xref="GI:398364970"
/db_xref="GeneID:851570"
CDS 461842..462516
/gene="TRP1"
/locus_tag="YDR007W"
/EC_number="5.3.1.24"
/note="Phosphoribosylanthranilate isomerase that catalyzes
the third step in tryptophan biosynthesis; in 2004, the
sequence of TRP1 from strain S228C was updated by changing
the previously annotated internal STOP (TAA) to serine
(TCA)"
/codon_start=1
/product="phosphoribosylanthranilate isomerase TRP1"
/protein_id="NP_010290.3"
/db_xref="GI:398364971"
/db_xref="SGD:S000002414"
/db_xref="GeneID:851570"
/translation="MSVINFTGSSGPLVKVCGLQSTEAAECALDSDADLLGIICVPNR
KRTIDPVIARKISSLVKAYKNSSGTPKYLVGVFRNQPKEDVLALVNDYGIDIVQLHGD
ESWQEYQEFLGLPVIKRLVFPKDCNILLSAASQKPHSFIPLFDSEAGGTGELLDWNSI
SDWVGRQESPESLHFMLAGGLTPENVGDALRLNGVIGVDVSGGVETNGVKDSNKIANF
VKNAKK"
rep_origin 462354..463192
/note="ARS1;
Early-firing autonomously replicating sequence; highly
efficient chromosomal replicator active in nearly every
cell cycle"
/db_xref="SGD:S000029652"
gene 463434..464996
/gene="GAL3"
/locus_tag="YDR009W"
/db_xref="GeneID:851572"
mRNA 463434..464996
/gene="GAL3"
/locus_tag="YDR009W"
/product="transcriptional regulator GAL3"
/transcript_id="NM_001180317.1"
/db_xref="GI:296143364"
/db_xref="GeneID:851572"
CDS 463434..464996
/gene="GAL3"
/locus_tag="YDR009W"
/note="Transcriptional regulator involved in activation of
the GAL genes in response to galactose; forms a complex
with Gal80p to relieve Gal80p inhibition of Gal4p; binds
galactose and ATP but does not have galactokinase
activity"
/codon_start=1
/product="transcriptional regulator GAL3"
/protein_id="NP_010292.1"
/db_xref="GI:6320212"
/db_xref="SGD:S000002416"
/db_xref="GeneID:851572"
/translation="MNTNVPIFSSPVRDLPRSFEQKHLAVVDAFFQTYHVKPDFIARS
PGRVNLIGEHIDYCDFSVLPLAIDVDMLCAVKILDEKNPSITLTNADPKFAQRKFDLP
LDGSYMAIDPSVSEWSNYFKCGLHVAHSYLKKIAPERFNNTPLVGAQIFCQSDIPTGG
GLSSAFTCAAALATIRANMGKNFDISKKDLTRITAVAEHYVGVNNGGMDQATSVYGEE
DHALYVEFRPKLKATPFKFPQLKNHEISFVIANTLVKSNKFETAPTNYNLRVIEVTVA
ANALATRYSVALPSHKDNSNSERGNLRDFMDAYYARYENQAQPWNGDIGTGIERLLKM
LQLVEESFSRKKSGFTVHEASTALNCSREEFTRDYLTTFPVRFQVLKLYQRAKHVYSE
SLRVLKALKMMTSATFHTDEDFFTDFGRLMNESQASCDKLYECSCIETNQICSIALAN
GSFGSRLTGAGWGGCTIHLVPSGANGNVEQVRKALIEKFYNVRYPDLTDEELKDAIIV
SKPALGTCLYEQ"
gene 465919..470424
/gene="SNQ2"
/locus_tag="YDR011W"
/db_xref="GeneID:851574"
mRNA 465919..470424
/gene="SNQ2"
/locus_tag="YDR011W"
/product="ATP-binding cassette transporter SNQ2"
/transcript_id="NM_001180319.1"
/db_xref="GI:296143365"
/db_xref="GeneID:851574"
CDS 465919..470424
/gene="SNQ2"
/locus_tag="YDR011W"
/note="Plasma membrane ATP-binding cassette (ABC)
transporter, multidrug transporter involved in multidrug
resistance and resistance to singlet oxygen species"
/codon_start=1
/product="ATP-binding cassette transporter SNQ2"
/protein_id="NP_010294.1"
/db_xref="GI:6320214"
/db_xref="SGD:S000002418"
/db_xref="GeneID:851574"
/translation="MSNIKSTQDSSHNAVARSSSASFAASEESFTGITHDKDEQSDTP
ADKLTKMLTGPARDTASQISATVSEMAPDVVSKVESFADALSRHTTRSGAFNMDSDSD
DGFDAHAIFESFVRDADEQGIHIRKAGVTIEDVSAKGVDASALEGATFGNILCLPLTI
FKGIKAKRHQKMRQIISNVNALAEAGEMILVLGRPGAGCSSFLKVTAGEIDQFAGGVS
GEVAYDGIPQEEMMKRYKADVIYNGELDVHFPYLTVKQTLDFAIACKTPALRVNNVSK
KEYIASRRDLYATIFGLRHTYNTKVGNDFVRGVSGGERKRVSIAEALAAKGSIYCWDN
ATRGLDASTALEYAKAIRIMTNLLKSTAFVTIYQASENIYETFDKVTVLYSGKQIYFG
LIHEAKPYFAKMGYLCPPRQATAEFLTALTDPNGFHLIKPGYENKVPRTAEEFETYWL
NSPEFAQMKKDIAAYKEKVNTEKTKEVYDESMAQEKSKYTRKKSYYTVSYWEQVKLCT
QRGFQRIYGNKSYTVINVCSAIIQSFITGSLFYNTPSSTSGAFSRGGVLYFALLYYSL
MGLANISFEHRPILQKHKGYSLYHPSAEAIGSTLASFPFRMIGLTCFFIILFFLSGLH
RTAGSFFTIYLFLTMCSEAINGLFEMVSSVCDTLSQANSISGILMMSISMYSTYMIQL
PSMHPWFKWISYVLPIRYAFESMLNAEFHGRHMDCANTLVPSGGDYDNLSDDYKVCAF
VGSKPGQSYVLGDDYLKNQFQYVYKHTWRNFGILWCFLLGYVVLKVIFTEYKRPVKGG
GDALIFKKGSKRFIAHADEESPDNVNDIDAKEQFSSESSGANDEVFDDLEAKGVFIWK
DVCFTIPYEGGKRMLLDNVSGYCIPGTMTALMGESGAGKTTLLNTLAQRNVGIITGDM
LVNGRPIDASFERRTGYVQQQDIHIAELTVRESLQFSARMRRPQHLPDSEKMDYVEKI
IRVLGMEEYAEALVGEVGCGLNVEQRKKLSIGVELVAKPDLLLFLDEPTSGLDSQSSW
AIIQLLRKLSKAGQSILCTIHQPSATLFEEFDRLLLLRKGGQTVYFGDIGKNSATILN
YFERNGARKCDSSENPAEYILEAIGAGATASVKEDWHEKWLNSVEFEQTKEKVQDLIN
DLSKQETKSEVGDKPSKYATSYAYQFRYVLIRTSTSFWRSLNYIMSKMMLMLVGGLYI
GFTFFNVGKSYVGLQNAMFAAFISIILSAPAMNQIQGRAIASRELFEVRESQSNMFHW
SLVLITQYLSELPYHLFFSTIFFVSSYFPLRIFFEASRSAVYFLNYCIMFQLYYVGLG
LMILYMSPNLPSANVILGLCLSFMLSFCGVTQPVSLMPGFWTFMWKASPYTYFVQNLV
GIMLHKKPVVCKKKELNYFNPPNGSTCGEYMKPFLEKATGYIENPDATSDCAYCIYEV
GDNYLTHISSKYSYLWRNFGIFWIYIFFNIIAMVCVYYLFHVRQSSFLSPVSILNKIK
NIRKKKQ"
gene 471853..472941
/gene="RPL4B"
/locus_tag="YDR012W"
/db_xref="GeneID:851575"
mRNA 471853..472941
/gene="RPL4B"
/locus_tag="YDR012W"
/product="ribosomal 60S subunit protein L4B"
/transcript_id="NM_001180320.3"
/db_xref="GI:398364990"
/db_xref="GeneID:851575"
CDS 471853..472941
/gene="RPL4B"
/locus_tag="YDR012W"
/note="Ribosomal 60S subunit protein L4B; homologous to
mammalian ribosomal protein L4 and bacterial L4; RPL4B has
a paralog, RPL4A, that arose from the whole genome
duplication"
/codon_start=1
/product="ribosomal 60S subunit protein L4B"
/protein_id="NP_010295.3"
/db_xref="GI:398364991"
/db_xref="SGD:S000002419"
/db_xref="GeneID:851575"
/translation="MSRPQVTVHSLTGEATANALPLPAVFSAPIRPDIVHTVFTSVNK
NKRQAYAVSEKAGHQTSAESWGTGRAVARIPRVGGGGTGRSGQGAFGNMCRGGRMFAP
TKTWRKWNVKVNHNEKRYATASAIAATAVASLVLARGHRVEKIPEIPLVVSTDLESIQ
KTKEAVAALKAVGAHSDLLKVLKSKKLRAGKGKYRNRRWTQRRGPLVVYAEDNGIVKA
LRNVPGVETANVASLNLLQLAPGAHLGRFVIWTEAAFTKLDQVWGSETVASSKVGYTL
PSHIISTSDVTRIINSSEIQSAIRPAGQATQKRTHVLKKNPLKNKQVLLRLNPYAKVF
AAEKLGSKKAEKTGTKPAAVFAETLKHD"
gene 473157..473783
/gene="PSF1"
/locus_tag="YDR013W"
/gene_synonym="CDC101"
/db_xref="GeneID:851576"
mRNA 473157..473783
/gene="PSF1"
/locus_tag="YDR013W"
/gene_synonym="CDC101"
/product="Psf1p"
/transcript_id="NM_001180321.3"
/db_xref="GI:398365002"
/db_xref="GeneID:851576"
CDS 473157..473783
/gene="PSF1"
/locus_tag="YDR013W"
/gene_synonym="CDC101"
/note="Subunit of the GINS complex (Sld5p, Psf1p, Psf2p,
Psf3p), which is localized to DNA replication origins and
implicated in assembly of the DNA replication machinery"
/codon_start=1
/product="Psf1p"
/protein_id="NP_010296.3"
/db_xref="GI:398365003"
/db_xref="SGD:S000002420"
/db_xref="GeneID:851576"
/translation="MYGDLGNKLVLEAKRTKQLYARSNQDVNLPMYHEDIIRNILKEV
SNLRKNTEYLKEQQQLGMLDDKVAKCQYFVTLLCMERNKRCLLAYQRLRTDILDSMAW
NNNGLDLMSSITFSQQDTNNLSHQEQEYLKEYCDLITDLKSGDLVDIDLSGSLVPPSD
VFIDVRVLKDAGEIQTEYGVFNLIKDSQFFVRQSDVERLIQQGYLQKI"
gene 474046..475989
/gene="RAD61"
/locus_tag="YDR014W"
/gene_synonym="WPL1"
/db_xref="GeneID:851577"
mRNA 474046..475989
/gene="RAD61"
/locus_tag="YDR014W"
/gene_synonym="WPL1"
/product="Rad61p"
/transcript_id="NM_001180322.1"
/db_xref="GI:296143368"
/db_xref="GeneID:851577"
CDS 474046..475989
/gene="RAD61"
/locus_tag="YDR014W"
/gene_synonym="WPL1"
/note="Subunit of a complex (Scc3p, Pds5p, Rad61p) that
inhibits sister chromatid cohesion; inhibited by
Eco1p-acetylated cohesin subunits Smc3p and Mcd1p; related
to the human Wapl protein that controls the association of
cohesin with chromatin"
/codon_start=1
/product="Rad61p"
/protein_id="NP_010297.1"
/db_xref="GI:6320217"
/db_xref="SGD:S000002421"
/db_xref="GeneID:851577"
/translation="MRAYGKRGPVLRTPFRSNKGLPSSSDVEFSDDDVNSVIPDVSST
ISSSIADHPIEGLLDEPRKAQDSSSSFDGANEKPSSQLDSKRNDQNVKIITSSDTSMA
FMKDEKLSAFNFLDGSKASKRKRRRTYQKHDANITSSIEPDVQDEDSITMHNEFESIR
KIYNDINEFILKLPRADDDILNKMLENEMKMDDSIENNSIRTSKDKKYGKFRTILINK
NKENEIMGEEVDQKANTLSLNNADNSNAEKEGLTSTNHYNELKNMGDTIKYQDDIEFL
LSNSKSNDNTTVPINEYFKKLLNLSLMIINDEEFFQYAKRYFKKEIIKLSFAQFRSDF
PELILLQGYLLHKVSESQSDFPPSFDNFSIELSKDDGKIRTKKNKHIKKLSHLNFEDF
LRKTQFKTGLYYSLSLWEMHGNLSLDIIKRISILASNKDLFSRHVKTFIPLLEKLITA
SEFCHMYIEQPEMFDSLISNLNNQFKDMLDDDSLIKILILLTNMEVHNYTLWKEADMI
FQSSMNTILESIHPLTDAKVDNILLHLGLCLNICSRENSRLKLDGKLWYDMKTIFVKM
IRDGSDTENRLVQGLFYLNFSFLIKQRKENSNLDPGELNLLLVELEAFKSETSQFNEG
ISNKIEIALNYLKSIYTSERITI"
gene 477797..478285
/gene="HED1"
/locus_tag="YDR014W-A"
/db_xref="GeneID:4036073"
mRNA 477797..478285
/gene="HED1"
/locus_tag="YDR014W-A"
/product="Hed1p"
/transcript_id="NM_001184688.1"
/db_xref="GI:296143369"
/db_xref="GeneID:4036073"
CDS 477797..478285
/gene="HED1"
/locus_tag="YDR014W-A"
/note="Meiosis-specific protein that down-regulates
Rad51p-mediated mitotic recombination when the meiotic
recombination machinery is impaired; early meiotic gene,
transcribed specifically during meiotic prophase"
/codon_start=1
/product="Hed1p"
/protein_id="NP_001035220.1"
/db_xref="GI:93117372"
/db_xref="SGD:S000113613"
/db_xref="GeneID:4036073"
/translation="MQQRSNRRSCSYIPLGVHNNAEKSLCTEVAPARKNKRSITTSPI
VNINVVERRLFNLELEKQQLRAKNLSENTGGGSPNGGAYLDAKKGVREQDQYQGGPSK
ELDRLQPPPSMKKSPPRKKKSLKDLIYETNKTFYQVDSNKVKYKVGLSKKQLLPSKTV
DN"
gene complement(478474..478758)
/gene="DAD1"
/locus_tag="YDR016C"
/db_xref="GeneID:851579"
mRNA complement(478474..478758)
/gene="DAD1"
/locus_tag="YDR016C"
/product="Dad1p"
/transcript_id="NM_001180324.3"
/db_xref="GI:398365022"
/db_xref="GeneID:851579"
CDS complement(478474..478758)
/gene="DAD1"
/locus_tag="YDR016C"
/note="Essential subunit of the Dam1 complex (aka DASH
complex), couples kinetochores to the force produced by MT
depolymerization thereby aiding in chromosome segregation;
is transferred to the kinetochore prior to mitosis"
/codon_start=1
/product="Dad1p"
/protein_id="NP_010299.3"
/db_xref="GI:398365023"
/db_xref="SGD:S000002423"
/db_xref="GeneID:851579"
/translation="MMASTSNDEEKLISTTDKYFIEQRNIVLQEINETMNSILNGLNG
LNISLESSIAVGREFQSVSDLWKTLYDGLESLSDEAPIDEQPTLSQSKTK"
gene complement(479115..482267)
/gene="KCS1"
/locus_tag="YDR017C"
/db_xref="GeneID:851580"
mRNA complement(479115..482267)
/gene="KCS1"
/locus_tag="YDR017C"
/product="inositol polyphosphate kinase KCS1"
/transcript_id="NM_001180325.3"
/db_xref="GI:398365024"
/db_xref="GeneID:851580"
CDS complement(479115..482267)
/gene="KCS1"
/locus_tag="YDR017C"
/EC_number="2.7.4.21"
/note="Inositol hexakisphosphate (IP6) and inositol
heptakisphosphate (IP7) kinase; generation of high energy
inositol pyrophosphates by Kcs1p is required for many
processes such as vacuolar biogenesis, stress response and
telomere maintenance"
/codon_start=1
/product="inositol polyphosphate kinase KCS1"
/protein_id="NP_010300.3"
/db_xref="GI:398365025"
/db_xref="SGD:S000002424"
/db_xref="GeneID:851580"
/translation="MDTSHEIHDKIPDTLREQQQHLRQKESEGCITTLKDLNVPETKK
LSSVLHGRKASTYLRIFRDDECLADNNNGVDSNNGGSVTCADKITRSEATPKSVPEGL
QVSEKKNNPDTLSSSLSSFILSNHEEPAIKPNKHVAHRNNITETGQGSGEDIAKQQSH
QPQVLHHQTSLKPIQNVDEGCISPKSTYQESLHGISEDLTLKPVSSATYYPHKSKADS
GYEEKDKMENDIDTIQPATINCASGIATLPSSYNRHTFKVKTYSTLSQSLRQENVNNR
SNEKKPQQFVPHSESIKEKPNTFEQDKEGEQADEEEDEGDNEHREYPLAVELKPFTNR
VGGHTAIFRFSKRAVCKALVNRENRWYENIELCHKELLQFMPRYIGVLNVRQHFQSKD
DFLSDLDQENNGKNDTSNENKDIEVNHNNNDDIALNTEPTGTPLTHIHSFPLEHSSRQ
VLEKEHPEIESVHPHVKRSLSSSNQPSLLPEVVLNDNRHIIPESLWYKYSDSPNSAPN
DSYFSSSSSHNSCSFGERGNTNKLKRRDSGSTMINTELKNLVIREVFAPKCFRRKRNS
NTTTMGNHNARLGSSPSFLTQKSRASSHDASNTSMKTLGDSSSQASLQMDDSKVNPNL
QDPFLKKSLHEKISNALDGSHSVMDLKQFHKNEQIKHKNSFCNSLSPILTATNSRDDG
EFATSPNYISNAQDGVFDMDEDTGNETINMDNHGCHLDSGKNMIIKSLAYNVSNDYSH
HDIESITFEETSHTIVSKFILLEDLTRNMNKPCALDLKMGTRQYGVDAKRAKQLSQRA
KCLKTTSRRLGVRICGLKVWNKDYYITRDKYFGRRVKVGWQFARVLARFLYDGKTIES
LIRQIPRLIKQLDTLYSEIFNLKGYRLYGASLLLMYDGDANKSNSKRKKAANVKVNLI
DFARCVTKEDAMECMDKFRIPPKSPNIEDKGFLRGVKSLRFYLLLIWNYLTSDMPLIF
DEVEMNDMISEEADSNSFTSATGSKINFNSKWDWLDEFDKEDEEMYNDPNSKLRQKWR
KYELIFDAEPRYNDDAQVSD"
gene complement(482670..483860)
/locus_tag="YDR018C"
/db_xref="GeneID:851581"
mRNA complement(482670..483860)
/locus_tag="YDR018C"
/product="putative acyltransferase"
/transcript_id="NM_001180326.1"
/db_xref="GI:296143372"
/db_xref="GeneID:851581"
CDS complement(482670..483860)
/locus_tag="YDR018C"
/EC_number="2.3.-.-"
/note="Probable membrane protein with three predicted
transmembrane domains; homologous to Ybr042cp, similar to
C. elegans F55A11.5 and maize 1-acyl-glycerol-3-phosphate
acyltransferase"
/codon_start=1
/product="putative acyltransferase"
/protein_id="NP_010301.1"
/db_xref="GI:6320221"
/db_xref="SGD:S000002425"
/db_xref="GeneID:851581"
/translation="MKHSQKYRRYGIYEKTGNPFIKGLQRLLIACLFISGSLSIVVFQ
ICLQVLLPWSKIRFQNGINQSKKAFIVLLCMILNMVAPSSLNVTFETSRPLKNSSNAK
PCFRFKDRAIIIANHQMYADWIYLWWLSFVSNLGGNVYIILKKALQYIPLLGFGMRNF
KFIFLSRNWQKDEKALTNSLVSMDLNARCKGPLTNYKSCYSKTNESIAAYNLIMFPEG
TNLSLKTREKSEAFCQRAHLDHVQLRHLLLPHSKGLKFAVEKLAPSLDAIYDVTIGYS
PALRTEYVGTKFTLKKIFLMGVYPEKVDFYIREFRVNEIPLQDDEVFFNWLLGVWKEK
DQLLEDYYNTGQFKSNAKNDNQSIVVTTQTTGFQHETLTPRILSYYGFFAFLILVFVM
KKNH"
rep_origin 483852..484096
/note="ARS417;
Autonomously Replicating Sequence"
/db_xref="SGD:S000118434"
gene complement(484163..485365)
/gene="GCV1"
/locus_tag="YDR019C"
/gene_synonym="GSD1"
/db_xref="GeneID:851582"
mRNA complement(484163..485365)
/gene="GCV1"
/locus_tag="YDR019C"
/gene_synonym="GSD1"
/product="glycine decarboxylase subunit T"
/transcript_id="NM_001180327.1"
/db_xref="GI:296143373"
/db_xref="GeneID:851582"
CDS complement(484163..485365)
/gene="GCV1"
/locus_tag="YDR019C"
/gene_synonym="GSD1"
/EC_number="2.1.2.10"
/note="T subunit of the mitochondrial glycine
decarboxylase complex, required for the catabolism of
glycine to 5,10-methylene-THF; expression is regulated by
levels of levels of 5,10-methylene-THF in the cytoplasm"
/codon_start=1
/product="glycine decarboxylase subunit T"
/protein_id="NP_010302.1"
/db_xref="GI:6320222"
/db_xref="SGD:S000002426"
/db_xref="GeneID:851582"
/translation="MSIIKKIVFKRFNSTLKKTALHDLHVSLGGTMVPYAGYSMPVLY
KGQTHIESHNWTRTNAGLFDVSHMLQSKLSGPHSVKFLQRVTPTDFNALPVGSGTLSV
LLNPQGGVVDDTIITKENDDNEFYIVTNAGCAERDTEFFHDELQNGSTLDCQWKIIEG
RSLLALQGPKAKDVLEPLLSKTAPGKDLKELFFGQRHEFALKDGSLVQIARGGYTGED
GFEISIANEKAVEFAEQLLANPVMKPIGLAARDSLRLEAGMCLYGHELDESITPVEAA
LNWVISKSRRDLVDQKYWFNGYAKIMDQLNNKTYSKVRVGFKYLKKGPAARNGVKIFL
PDAETEVGLVTSGSASPTLNNINIGQAYVQKGYHKKGTKLLVQVRNKFYPIELAKMPL
VPTHYYKQ"
gene complement(485746..486444)
/gene="DAS2"
/locus_tag="YDR020C"
/gene_synonym="RRT3"
/db_xref="GeneID:851583"
mRNA complement(485746..486444)
/gene="DAS2"
/locus_tag="YDR020C"
/gene_synonym="RRT3"
/product="putative uridine kinase DAS2"
/transcript_id="NM_001180328.3"
/db_xref="GI:398365046"
/db_xref="GeneID:851583"
CDS complement(485746..486444)
/gene="DAS2"
/locus_tag="YDR020C"
/gene_synonym="RRT3"
/EC_number="2.7.1.48"
/note="hypothetical protein; non-essential gene identified
in a screen for mutants with increased levels of rDNA
transcription; weak similarity with uridine kinases and
with phosphoribokinases"
/codon_start=1
/product="putative uridine kinase DAS2"
/protein_id="NP_010303.3"
/db_xref="GI:398365047"
/db_xref="SGD:S000002427"
/db_xref="GeneID:851583"
/translation="MDRKAVEEKRIVISIGGGHATGVGAIALDLQNTFKSLYNSINIR
VINLDNMIEGNIKSYNNNDYDFDNILNLVYEKHAVTSQNDMIQHDYEDPIDLIIVCGC
YALYDKRINEISQLKVFLDSDADKRLISLIKKKNVGSNEQLAQLITEYMDHLRPEMQQ
YIEPTRTFADLIIPSTNENLGRAVLVDGIVKAIEDTKSQIEGNNTNNKIRPRLWDFEA
ETMDLEKDRYYDLS"
gene 486804..488003
/gene="FAL1"
/locus_tag="YDR021W"
/db_xref="GeneID:851584"
mRNA 486804..488003
/gene="FAL1"
/locus_tag="YDR021W"
/product="Fal1p"
/transcript_id="NM_001180329.3"
/db_xref="GI:398365052"
/db_xref="GeneID:851584"
CDS 486804..488003
/gene="FAL1"
/locus_tag="YDR021W"
/EC_number="3.6.1.-"
/note="Nucleolar protein required for maturation of 18S
rRNA, member of the eIF4A subfamily of DEAD-box
ATP-dependent RNA helicases"
/codon_start=1
/product="Fal1p"
/protein_id="NP_010304.3"
/db_xref="GI:398365053"
/db_xref="SGD:S000002428"
/db_xref="GeneID:851584"
/translation="MSFDREEDQKLKFKTSKKLKVSSTFESMNLKDDLLRGIYSYGFE
APSSIQSRAITQIISGKDVIAQAQSGTGKTATFTIGLLQAIDLRKKDLQALILSPTRE
LASQIGQVVKNLGDYMNVNAFAITGGKTLKDDLKKMQKHGCQAVSGTPGRVLDMIKKQ
MLQTRNVQMLVLDEADELLSETLGFKQQIYDIFAKLPKNCQVVVVSATMNKDILEVTR
KFMNDPVKILVKRDEISLEGIKQYVVNVDKEEWKFDTLCDIYDSLTITQCVIFCNTKK
KVDWLSQRLIQSNFAVVSMHGDMKQEERDKVMNDFRTGHSRVLISTDVWARGIDVQQV
SLVINYDLPEIIENYIHRIGRSGRFGRKGVAINFITKADLAKLREIEKFYSIKINPMP
ANFAELS"
gene complement(488072..488662)
/gene="ATG31"
/locus_tag="YDR022C"
/gene_synonym="CIS1"
/db_xref="GeneID:851585"
mRNA complement(488072..488662)
/gene="ATG31"
/locus_tag="YDR022C"
/gene_synonym="CIS1"
/product="Atg31p"
/transcript_id="NM_001180330.1"
/db_xref="GI:296143376"
/db_xref="GeneID:851585"
CDS complement(488072..488662)
/gene="ATG31"
/locus_tag="YDR022C"
/gene_synonym="CIS1"
/note="Autophagy-specific protein required for
autophagosome formation; may form a complex with Atg17p
and Atg29p that localizes other proteins to the
pre-autophagosomal structure; high-copy suppressor of CIK1
deletion"
/codon_start=1
/product="Atg31p"
/protein_id="NP_010305.1"
/db_xref="GI:6320225"
/db_xref="SGD:S000002429"
/db_xref="GeneID:851585"
/translation="MNVTVTVYDKNVKYRLEENIKNNKGPSNDDQPAYNNESKSTDGS
DYAMFPTNIKYIFEDNNDELVDSSDAALTAGIDKVGDELENVIIVQLDESGSLEDITL
ISDQYELLSHRTNSLSLEENQMRTLSSHGDDKSNDEEEELSVDSDRFRVDSDIELDVI
SQFCDLSPFLRDLSLNDLIKLYVTQNEQLQMLSNSV"
gene complement(488797..488870)
/locus_tag="tV(UAC)D"
/db_xref="GeneID:851586"
tRNA complement(488797..488870)
/locus_tag="tV(UAC)D"
/product="tRNA-Val"
/note="Valine tRNA (tRNA-Val), predicted by tRNAscan-SE
analysis"
/db_xref="SGD:S000006770"
/db_xref="GeneID:851586"
gene 489508..490896
/gene="SES1"
/locus_tag="YDR023W"
/db_xref="GeneID:851587"
mRNA 489508..490896
/gene="SES1"
/locus_tag="YDR023W"
/product="serine--tRNA ligase SES1"
/transcript_id="NM_001180331.1"
/db_xref="GI:296143377"
/db_xref="GeneID:851587"
CDS 489508..490896
/gene="SES1"
/locus_tag="YDR023W"
/EC_number="6.1.1.11"
/note="Cytosolic seryl-tRNA synthetase, class II
aminoacyl-tRNA synthetase that aminoacylates tRNA(Ser),
displays tRNA-dependent amino acid recognition which
enhances discrimination of the serine substrate, interacts
with peroxin Pex21p"
/codon_start=1
/product="serine--tRNA ligase SES1"
/protein_id="NP_010306.1"
/db_xref="GI:6320226"
/db_xref="SGD:S000002430"
/db_xref="GeneID:851587"
/translation="MLDINQFIEDKGGNPELIRQSQKARNASVEIVDEIISDYKDWVK
TRFELDELNKKFNKLQKDIGLKFKNKEDASGLLAEKEKLTQQKKELTEKEQQEDKDLK
KKVFQVGNIVHPSVVVSNDEENNELVRTWKPEDLEAVGPIASVTGKPASLSHHEILLR
LDGYDPDRGVKICGHRGYFFRNYGVFLNQALINYGLQFLAAKGYIPLQAPVMMNKELM
SKTAQLSEFDEELYKVIDGEDEKYLIATSEQPISAYHSGEWFEKPQEQLPIHYVGYSS
CFRREAGSHGKDAWGVFRVHAFEKIEQFVITEPEKSWEEFEKMISYSEEFYKSLKLPY
RIVGIVSGELNNAAAKKYDLEAWFPYQKEYKELVSCSNCTDYQSRNLEIRCGIKKMGD
REKKYVHCLNSTLAATQRALCCILENYQTEDGLVVPEVLRKYIPGEPEFLPFVNELPK
NSTSSKDKKKKN"
gene 491515..492324
/gene="RPS11A"
/locus_tag="YDR025W"
/db_xref="GeneID:851589"
mRNA join(491515..491559,491899..492324)
/gene="RPS11A"
/locus_tag="YDR025W"
/product="ribosomal 40S subunit protein S11A"
/transcript_id="NM_001180333.3"
/db_xref="GI:398365070"
/db_xref="GeneID:851589"
CDS join(491515..491559,491899..492324)
/gene="RPS11A"
/locus_tag="YDR025W"
/note="Protein component of the small (40S) ribosomal
subunit; homologous to mammalian ribosomal protein S11 and
bacterial S17; RPS11A has a paralog, RPS11B, that arose
from the whole genome duplication"
/codon_start=1
/product="ribosomal 40S subunit protein S11A"
/protein_id="NP_010308.3"
/db_xref="GI:398365071"
/db_xref="SGD:S000002432"
/db_xref="GeneID:851589"
/translation="MSTELTVQSERAFQKQPHIFNNPKVKTSKRTKRWYKNAGLGFKT
PKTAIEGSYIDKKCPFTGLVSIRGKILTGTVVSTKMHRTIVIRRAYLHYIPKYNRYEK
RHKNVPVHVSPAFRVQVGDIVTVGQCRPISKTVRFNVVKVSAAAGKANKQFAKF"
gene complement(492556..494268)
/gene="NSI1"
/locus_tag="YDR026C"
/db_xref="GeneID:851590"
mRNA complement(492556..494268)
/gene="NSI1"
/locus_tag="YDR026C"
/product="Nsi1p"
/transcript_id="NM_001180334.3"
/db_xref="GI:398365076"
/db_xref="GeneID:851590"
CDS complement(492556..494268)
/gene="NSI1"
/locus_tag="YDR026C"
/note="RNA polymerase I termination factor; binds to rDNA
terminator element, required for efficient Pol I
termination; required for rDNA silencing at NTS1;
facilities association of Sir2p with NTS1, contributes to
rDNA stability and cell longevity; interacts physically
with Fob1p and RENT subunits, Sir2p and Net1p; may
interact with ribosomes, based on co-purification
experiments; Myb-like DNA-binding protein; NSI1 has a
paralog, REB1, that arose from the whole genome
duplication"
/codon_start=1
/product="Nsi1p"
/protein_id="NP_010309.3"
/db_xref="GI:398365077"
/db_xref="SGD:S000002433"
/db_xref="GeneID:851590"
/translation="MDSVSNLKSTNFQNNNDPKESVEEAVLRYVGVDLKNHIKKTKKK
LKKQKKRKHGSKMSHEDEDTDMDWYLKTSGSKDLRKVDDIEPNSVAVAAVAAAYNSSM
REKDKRSCHKKSSNSRSERKKHRKRKSSKERKAKIKMVLDPQLTTLDDGITTTAFLPD
DLIAETAFDKYVDTEKAYLAKHPSKSLEVNEDDKENNFNNNSSTLVRIYTDLEGIPND
GSYIKRTPKIPEKDVKSDDLILAPEENNGDTALLRSDIVKASVIDGAITKSIGKKFTP
SEENALDQFIEEYMKIRGLDRRQMCERIWSTDGVIRDGFWANISKVLPYRTRSSIYKH
IRRKYHIFEQRGKWTPEEDQELARLCLEKEGHWTEVGKLLGRMPEDCRDRWRNYMKCG
SKRGSKRWSKEEEELLTTVVNEMIEEAHQYQRMKALEAANKNDRYNQMYSRGPKGKRI
SDNPTFKDMINWTVVSERMSGTRSRIQCRYKWNKLVTDEAARSMLSIPVSERKWLLER
LKQLPKTSYSNIDWNSIATYKPGYPRTGLELRLCYEQMREKIHDFKGRSTAEIIDSLL
EQIN"
gene complement(494649..497318)
/gene="VPS54"
/locus_tag="YDR027C"
/gene_synonym="CGP1; LUV1; TCS3"
/db_xref="GeneID:851591"
mRNA complement(494649..497318)
/gene="VPS54"
/locus_tag="YDR027C"
/gene_synonym="CGP1; LUV1; TCS3"
/product="Vps54p"
/transcript_id="NM_001180335.1"
/db_xref="GI:296143380"
/db_xref="GeneID:851591"
CDS complement(494649..497318)
/gene="VPS54"
/locus_tag="YDR027C"
/gene_synonym="CGP1; LUV1; TCS3"
/note="Component of the GARP (Golgi-associated retrograde
protein) complex, Vps51p-Vps52p-Vps53p-Vps54p, which is
required for the recycling of proteins from endosomes to
the late Golgi; potentially phosphorylated by Cdc28p"
/codon_start=1
/product="Vps54p"
/protein_id="NP_010310.1"
/db_xref="GI:6320230"
/db_xref="SGD:S000002434"
/db_xref="GeneID:851591"
/translation="MSISETPHNKSQGLQKAAGRPKIVVPEGSPSRNSDSGSFTIEGD
TSLNDDLLSISGSVTPRARRSSRLSLDSITPRRSFDSRTLSVANSRSFGFENETHSGS
MDFSPLGNNSIYEIVMNTRRKNWLNYPTVADIPQVSLSKNDLDDHWKTHVIEYVKNIK
SDYQIFQSTNNIRNMNQMEQLKELREGENMHEESFEANLRQGDAELINSIPDFYFSDK
FQLDNPRTFHKVLDAIDLFLTKLDMKRQAERDEAFSELRDRLNDFLDIVETLLVTEIS
KSSHKFFHALSEVDNIQKRALDTMSELKELAQNIKTIDAENIRKKISHLEMIFKRKNV
EKLEQGLLQAKLVLNKTDECKSMYEENKLDNCLELIKSIDYLIKGDDSINEDVQSWTR
CWPYKLSNLRTIPALSATREFLTNMKIEIGGKFSLQLSILLIDDLRSFCKSIKPKETL
HRIQTGSNDKKQTIFTDNFSSKITELIVRLNRCEELTSAFDLYREKSITELKSIIKIY
LPTENAHADNNHDEKHLNNGSTSGSKLSRLIKEQTPAEFQSMLVNIFTHALEALRRLY
GHQKLLLDISLNELASVKSPNENQHNMITQLDIRTGINEIIRIIQLRTGKIIAVRREL
NLSLRYDYFLKFYAICVIFIQECEVLSGEFLTKYLSNVLASQIKHYANAQSSKNYRNI
KKKIDAEEWIPYIVDSSIQSDVNDIVSSIDIDPLSWTTILDMVGGSHDCENGRSEDKE
KDEGNETYQGHRKSVVVGDKTFVASSSLLATIEVIKELMVLSINLPSIYLSNFEKLCY
DALQYYNSSAMASVTQPGNSLLKTGRNLSIMGESLDCLAEFVIIVQRFYQRLSNSNRD
FEPFDASHYTTLLGQFQASSNKIYMANAPPPPV"
gene complement(497835..500879)
/gene="REG1"
/locus_tag="YDR028C"
/gene_synonym="HEX2; PZF240; SPP43; SRN1"
/db_xref="GeneID:851592"
mRNA complement(497835..500879)
/gene="REG1"
/locus_tag="YDR028C"
/gene_synonym="HEX2; PZF240; SPP43; SRN1"
/product="Reg1p"
/transcript_id="NM_001180336.1"
/db_xref="GI:296143381"
/db_xref="GeneID:851592"
CDS complement(497835..500879)
/gene="REG1"
/locus_tag="YDR028C"
/gene_synonym="HEX2; PZF240; SPP43; SRN1"
/note="Regulatory subunit of type 1 protein phosphatase
Glc7p; involved in negative regulation of
glucose-repressible genes; involved in regulation of the
nucleocytoplasmic shuttling of Hxk2p"
/codon_start=1
/product="Reg1p"
/protein_id="NP_010311.1"
/db_xref="GI:6320231"
/db_xref="SGD:S000002435"
/db_xref="GeneID:851592"
/translation="MSTNLANYFAGKKDIENEHVNRNASHESNSKSDVKISGNDNDND
EDMGPSVSMAVQAKNDDDFHKSTFNLKRTRSMGLLDEYIDPTKKLLGRSDDLYDNDNE
YYDNSSNNSSSNSSDDDYDDGYQEHSTSVSPPPADNDSYLIPQDDNDVVVEPERHVDY
LSHEWKESEISNSWKYIILKKKKRDVDLVNAARLENASWRTWAKARNNLKTVSPEVVN
WSKDSDVTWLYGPIVRDSEGNAQSEEEHDLERGYGSDDENSKRISMPTKNSKSIAAAP
KPILKKRTVTEIIEDNALWKLNEARKHMTEMKHASVIMDPNGNKNVHDDFDALAAQVN
AQYYHYPKESNSSVSLKSQHSDKKDNSTIPNPVGENSNGGGDKGEEDLHLKSALHVQN
NRSTAQSNKSILENSTNDRKANLDQNLNSPDNNRFPSSTSSSNRDNENNSMGLSSILT
SNPSEKSNKPTKNRHIHFNDRVEQCMALRYPASQSEDDESDDENKQYVDVNNNANVTT
INNNRTPLLAIQHKSIPINSATEHLNKNTSDDDTSSQSSSSSHSDDEEHGGLYINARF
SRRSDSGVHSPITDNSSVASSTTSRAHVRPIIKLLPDTTLNYGSDEESDNGEFNGYGN
AVSHNVNTSRGYDYIYDYNSVYTGDTSSFLPVDSCDIVDVPEGMDLQTAIADDNASNY
EFNNAVESKEKHVPQLHKASANNTTRQHGSHMLLYDDDNYSSSSDSEQQFIEDSQYNS
SDDEEEEDDDDQEVDDNHDEGLSLRRTLSLGKSGSTNSLYDLAQPSLSSATPQQKNPT
NFTGGKTDVDKDAQLAVRPYPLKRNSSSGNFIFNSDSEEESSSEEEQRPLPANSQLVN
RSVLKGSVTPANISSQKKKALPKQPKASDSSQSFRIVNNTPSPAEVGASDVAIEGYFS
PRNESIKSVVSGGNMMDHQDHSEMDTLAKGFENCHINNASKLKDKKVDSVQTTRKEAS
LTDSSNESLHKVVQNARGMASKYLHSWKKSDVKPQENGNDSS"
gene complement(501753..503273)
/gene="RAD28"
/locus_tag="YDR030C"
/db_xref="GeneID:851594"
mRNA complement(501753..503273)
/gene="RAD28"
/locus_tag="YDR030C"
/product="Rad28p"
/transcript_id="NM_001180338.3"
/db_xref="GI:398365096"
/db_xref="GeneID:851594"
CDS complement(501753..503273)
/gene="RAD28"
/locus_tag="YDR030C"
/note="Protein involved in DNA repair, related to the
human CSA protein that is involved in
transcription-coupled repair nucleotide excision repair"
/codon_start=1
/product="Rad28p"
/protein_id="NP_010313.3"
/db_xref="GI:398365097"
/db_xref="SGD:S000002437"
/db_xref="GeneID:851594"
/translation="MDPFLEFRVGNISLNEFYRRTIQSEFERILEDPLSNMKNYRFSK
QSNYSTKEKTPLSIGVNCLDIDDTGQVLLGGGDDGSLSIWGLDESLHRNDEGEQELIN
KRLNYIKRQPHQSDDEPAQIMGYKNKRTRINDNNTMRLVHSFQTQRNKYRMYRQSSAA
VPVQRSHISNKTDSPIGFSETLSETDSEASISHHKYGITTLKWYKADNGMFFTGSNDK
TVKIWDTNRFEAVQDINLGYKINQIDNNVVDDSSLLVVASEDYYPRLIDLRTMNSGVT
ALGMGNQTRMQSEILCCKFNPVREQIIACGDMEGGVKLWDLRMRNRLYSELKRNKNRF
KTINNDDNDDQSDVYFSSNQSKAHLRCCSDIVWNSEGSELCSVGMDGKLNVWRPFTEI
LQPEGLASYSQLGTQDLSRIKYKKRVSRRLLWFDKFLLCITDNGEVEIYNTEEKKLWN
KLEYPMVNQVKKNQASHCQFSSMIVQTNIMNSVGLKLFFGTNNNTVSDGGSIFECS"
gene 503498..503863
/gene="MIC14"
/locus_tag="YDR031W"
/db_xref="GeneID:851595"
mRNA 503498..503863
/gene="MIC14"
/locus_tag="YDR031W"
/product="Mic14p"
/transcript_id="NM_001180339.3"
/db_xref="GI:398365108"
/db_xref="GeneID:851595"
CDS 503498..503863
/gene="MIC14"
/locus_tag="YDR031W"
/note="Mitochondrial intermembrane space hypothetical
protein; required for normal oxygen consumption; contains
twin cysteine-x9-cysteine motifs; protein abundance
increases in response to DNA replication stress"
/codon_start=1
/product="Mic14p"
/protein_id="NP_010314.4"
/db_xref="GI:398365109"
/db_xref="SGD:S000002438"
/db_xref="GeneID:851595"
/translation="MSDILDEIVIEDVVANCPQEFLQYHKCIRDNEENPGKCKDGRMI
LSTCIREKVPSVKSIMSECSEPMKKYDQCIRDNMGTRTINENCLGFLQDLRKCAELQV
KNKNIKPSINGVNLELIKD"
gene complement(504099..504695)
/gene="PST2"
/locus_tag="YDR032C"
/db_xref="GeneID:851596"
mRNA complement(504099..504695)
/gene="PST2"
/locus_tag="YDR032C"
/product="Pst2p"
/transcript_id="NM_001180340.1"
/db_xref="GI:296143384"
/db_xref="GeneID:851596"
CDS complement(504099..504695)
/gene="PST2"
/locus_tag="YDR032C"
/note="Protein with similarity to a family of
flavodoxin-like proteins; induced by oxidative stress in a
Yap1p dependent manner; the authentic, non-tagged protein
is detected in highly purified mitochondria in
high-throughput studies; protein abundance increases in
response to DNA replication stress"
/codon_start=1
/product="Pst2p"
/protein_id="NP_010315.1"
/db_xref="GI:6320235"
/db_xref="SGD:S000002439"
/db_xref="GeneID:851596"
/translation="MPRVAIIIYTLYGHVAATAEAEKKGIEAAGGSADIYQVEETLSP
EVVKALGGAPKPDYPIATQDTLTEYDAFLFGIPTRFGNFPAQWKAFWDRTGGLWAKGA
LHGKVAGCFVSTGTGGGNEATIMNSLSTLAHHGIIFVPLGYKNVFAELTNMDEVHGGS
PWGAGTIAGSDGSRSPSALELQVHEIQGKTFYETVAKF"
rep_origin 505343..505584
/note="ARS450;
Autonomously Replicating Sequence"
/db_xref="SGD:S000119069"
gene 508147..509109
/gene="MRH1"
/locus_tag="YDR033W"
/db_xref="GeneID:851597"
mRNA 508147..509109
/gene="MRH1"
/locus_tag="YDR033W"
/product="Mrh1p"
/transcript_id="NM_001180341.1"
/db_xref="GI:296143385"
/db_xref="GeneID:851597"
CDS 508147..509109
/gene="MRH1"
/locus_tag="YDR033W"
/note="Protein that localizes primarily to the plasma
membrane, also found at the nuclear envelope; the
authentic, non-tagged protein is detected in mitochondria
in a phosphorylated state; has similarity to Hsp30p and
Yro2p"
/codon_start=1
/product="Mrh1p"
/protein_id="NP_010316.1"
/db_xref="GI:6320236"
/db_xref="SGD:S000002440"
/db_xref="GeneID:851597"
/translation="MSTFETLIKRGGNEAIKINPPTGADFHITSRGSDWFWTCFCCYL
LFGLILTFLMFRKPVNDRFFYLTGIAPNFFMCIAYFTMASNLGWIPVKAKYNHVQTST
QKEHPGYRQIFYSRFVGWFLALPWPIIQICMLAGTPFWQMAFNVCITEFFTVCWLIAA
CVHSTYKWGYYTIGLGAAIVVSISVMTTSYNLVKQRDNDIRLTFLVFFSIIMFLWIIA
YPTCFGITDGGNVLQPDSAGIFYGIIDLILMCFIPTLLVPIANHFGADKLGYHFGPSD
AEAVMAPKAPVASPRPAATPNLSKDKKKKSKKSKKSKKSKKSEE"
gene complement(509737..512109)
/gene="LYS14"
/locus_tag="YDR034C"
/db_xref="GeneID:851598"
mRNA complement(509737..512109)
/gene="LYS14"
/locus_tag="YDR034C"
/product="Lys14p"
/transcript_id="NM_001180342.3"
/db_xref="GI:398365128"
/db_xref="GeneID:851598"
CDS complement(509737..512109)
/gene="LYS14"
/locus_tag="YDR034C"
/note="Transcriptional activator involved in regulation of
genes of the lysine biosynthesis pathway; requires
2-aminoadipate semialdehyde as co-inducer"
/codon_start=1
/product="Lys14p"
/protein_id="NP_010317.3"
/db_xref="GI:398365129"
/db_xref="SGD:S000002441"
/db_xref="GeneID:851598"
/translation="MFESVNLDENSPEDRELAKVLSPPGSYLSPASLDSGSSFTNSGT
STSCFEPKNNLPSLSFLNARAGSLGGIFNHKQMTSPSNSNIGGENVESTTSSNDGSNE
NAGHPTTSEQDQNADHPTISQADDNGHSSLTPNPAVTSTVTDKKGNTVKRKYSRNGCS
ECKRRRMKCDETKPTCWQCARLNRQCVYVLNPKNKKRRTSNAQRVKEFRKHSTSLDND
HNNARKRQHSSCKAEKKKKVRQNLSEDTTDPKPITDNGKNVPLDEIESLEIPNLDLTT
TMNGYDVNLLMQNLNDMVNMKLHDSYLLNEELKGLDLPDLDIPELLPASNVNSSVPIS
FLVNNVITFNTKLSSFKLGGIHDKYLKIFYYDCLDSIAPFFQNQGNPLRDILLSFAKN
EAYLLSSILATGASIAYRKSNNLEDERNYCAYLSHCLSLLGEQFKNESNVLNRIEPII
LTVIMLAWDCIYSMNSQWRSHLKGVTDLFKKINAGNSSKVLNVAKCWFKVMETFASIS
TVFGGSLIDNNDLDAIFDPYDYQYVDSLKFLNIMTPLNEFNLLRGHKEDFDLVIKEVF
KSLNTIRSTEKNYFSKEEGLFTKKLDYLLLSSQTSSEKSKDQISYFNTQKILVEIDKQ
LDYEFIDKSGIIPSDNQSHPRISNIHDNAIDMVTLKNGEEVAISWYDISHQTQVLSFL
LIVLLKLLGMPKESSTIQQVVKKIMSFFKFLDSDSPPQNSRTCYSNFAVLIAGLNAMD
EETRAIVKRYYKINGGKFQKLTEHNLNRLEKVWYGKNQNYRLEEQDVLTW"
LTR complement(512986..513258)
/note="Ty1 LTR"
/db_xref="SGD:S000006844"
LTR complement(513259..513590)
/note="Ty1 LTR"
/db_xref="SGD:S000006845"
mobile_element complement(513692..519647)
/note="YDRCTy2-1; Ty2 element, LTR retrotransposon of the
Copia (Pseudoviridae) group; contains co-transcribed genes
TYA Gag and TYB Pol, encoding proteins involved in
structure and function of virus-like particles, flanked by
two direct repeats"
/mobile_element_type="retrotransposon:YDRCTy2-1"
/db_xref="SGD:S000006862"
LTR complement(513692..514020)
/note="Ty2 LTR"
/db_xref="SGD:S000006846"
gene complement(514043..519356)
/locus_tag="YDR034C-D"
/db_xref="GeneID:851599"
mRNA complement(join(<514043..518062,518064..>519356))
/locus_tag="YDR034C-D"
/transcript_id="NM_001184379.3"
/db_xref="GI:398365134"
/db_xref="GeneID:851599"
CDS complement(join(514043..518062,518064..519356))
/locus_tag="YDR034C-D"
/EC_number="2.7.7.49"
/EC_number="3.4.23.-"
/EC_number="3.1.26.4"
/EC_number="2.7.7.7"
/ribosomal_slippage
/note="Retrotransposon TYA Gag and TYB Pol genes;
transcribed/translated as one unit; polyprotein is
processed to make a nucleocapsid-like protein (Gag),
reverse transcriptase (RT), protease (PR), and integrase
(IN); similar to retroviral genes"
/codon_start=1
/product="gag-pol fusion protein"
/protein_id="NP_058138.3"
/db_xref="GI:398365135"
/db_xref="SGD:S000007345"
/db_xref="GeneID:851599"
/translation="MESQQLSQNSPNLHGSAYASVTSKEVPSNQDPLAVSASNLPEFD
RDSTKVNSQQETTPGTSAVPENHHHVSPQPASVPPPQNGQYQQHGMMTPNKAMASNWA
HYQQPSMMTCSHYQTSPAYYQPDPHYPLPQYIPPLSTSSPDPIDLKNQHSEIPQAKTK
VGNNVLPPHTLTSEENFSTWVKFYIRFLKNSNLGDIIPNDQGEIKRQMTYEEHAYIYN
TFQAFAPFHLLPTWVKQILEINYADILTVLCKSVSKMQTNNQELKDWIALANLEYDGS
TSADTFEITVSTIIQRLKENNINVSDRLACQLILKGLSGDFKYLRNQYRTKTNMKLSQ
LFAEIQLIYDENKIMNLNKPSQYKQHSEYKNVSRTSPNTTNTKVTTRNYQRTNSSKPR
AAKAHNIATSSKFSRVNNDHINESTVSSQYLSDDNELSLGQQQKESKPTHTIDSNDEL
PDHLLIDSGASQTLVRSAHYLHHATPNSEINIVDAQKQDIPINAIGNLHFNFQNGTKT
SIKALHTPNIAYDLLSLSELANQNITACFTRNTLERSDGTVLAPIVKHGDFYWLSKKY
LIPSHISKLTINNVNKSKSVNKYPYPLIHRMLGHANFRSIQKSLKKNAVTYLKESDIE
WSNASTYQCPDCLIGKSTKHRHVKGSRLKYQESYEPFQYLHTDIFGPVHHLPKSAPSY
FISFTDEKTRFQWVYPLHDRREESILNVFTSILAFIKNQFNARVLVIQMDRGSEYTNK
TLHKFFTNRGITACYTTTADSRAHGVAERLNRTLLNDCRTLLHCSGLPNHLWFSAVEF
STIIRNSLVSPKNDKSARQHAGLAGLDITTILPFGQPVIVNNHNPDSKIHPRGIPGYA
LHPSRNSYGYIIYLPSLKKTVDTTNYVILQDKQSKLDQFNYDTLTFDDDLNRLTAHNQ
SFIEKNETEQSYDQNTESDHDYQSEIEINSDPLVNDFSSQSINPLQLDKEPVQKVRAP
KEVDADISEYNILPSTIRSRTPHIINKESTEMGGTIESDTTSPRHSSTFTARNQKRPG
SPNDMIDLTSQDRVNYGLENIKTTRLGGTEEPYIQRNSDTNIKYRTTNSTPSIDDRSS
NSESTTPIISIETKAACDNTPSIDTDPPEYRSSDHATPNIMPDKSSKNVTADSILDDL
PLPDLTNKSPTDTSDVSKDIPHIHSRQTNSSLGGMDDSNVLTTTKSKKRSLEDNETEI
EVSRDTWNNKNMRSLEPPRSKKRINLIAAIKGVKSIKPVRTTLRYDEAITYNEDNKEK
DRYIEAYHKEINQLLRMNTWDTNKYYDRNDIDPKKVINSMFIFNKKRDGTHKARFVAR
GDIQHPDTYDSDMQSNTVHHYALMTSLSIALDNDYYITQLDISSAYLYADIKEELYIR
PPPHLGLNDKLLRLRKSLYGLKQSGANWYETIKSYLINCCDMQEVRGWSCVFKNSQVT
ICLFVDDMILFSKDLNANKKIITTLKKQYDTKIINLGEGDNEIQYDILGLEIKYQRSK
YMKLGMEKSLTEKLPKLNVPLNPKGKKLRAPGQPGHYIDQDELEIDEDEYKEKVHEMQ
KLIGLASYVGYKFRFDLLYYINTLAQHILFPSRQVLDMTYELIQFMWDTRDKQLIWHK
NKPTKPDNKLVAISDASYGNQPYYKSQIGNIFLLNGKVIGGKSTKASLTCTSTTEAEI
HAVSEAIPLLNNLSHLVQELNKKPIIKGLLTDSRSTISIIKSTNEEKFRNRFFGTKAM
RLRDEVSGNNLYVYYIETKKNIADVMTKPLPIKTFKLLTNKWIH"
gene complement(518040..519356)
/locus_tag="YDR034C-C"
/db_xref="GeneID:851600"
mRNA complement(<518040..>519356)
/locus_tag="YDR034C-C"
/transcript_id="NM_001184378.1"
/db_xref="GI:296143388"
/db_xref="GeneID:851600"
CDS complement(518040..519356)
/locus_tag="YDR034C-C"
/note="Retrotransposon TYA Gag gene co-transcribed with
TYB Pol; translated as TYA or TYA-TYB polyprotein; Gag is
a nucleocapsid protein that is the structural constituent
of virus-like particles (VLPs); similar to retroviral Gag"
/codon_start=1
/product="gag protein"
/protein_id="NP_058139.1"
/db_xref="GI:7839149"
/db_xref="SGD:S000007344"
/db_xref="GeneID:851600"
/translation="MESQQLSQNSPNLHGSAYASVTSKEVPSNQDPLAVSASNLPEFD
RDSTKVNSQQETTPGTSAVPENHHHVSPQPASVPPPQNGQYQQHGMMTPNKAMASNWA
HYQQPSMMTCSHYQTSPAYYQPDPHYPLPQYIPPLSTSSPDPIDLKNQHSEIPQAKTK
VGNNVLPPHTLTSEENFSTWVKFYIRFLKNSNLGDIIPNDQGEIKRQMTYEEHAYIYN
TFQAFAPFHLLPTWVKQILEINYADILTVLCKSVSKMQTNNQELKDWIALANLEYDGS
TSADTFEITVSTIIQRLKENNINVSDRLACQLILKGLSGDFKYLRNQYRTKTNMKLSQ
LFAEIQLIYDENKIMNLNKPSQYKQHSEYKNVSRTSPNTTNTKVTTRNYQRTNSSKPR
AAKAHNIATSSKFSRVNNDHINESTVSSQYLSDDNELSLRPATERI"
LTR complement(519316..519647)
/note="Ty2 LTR"
/db_xref="SGD:S000006847"
gene 519743..519826
/locus_tag="tL(UAA)D"
/db_xref="GeneID:851601"
tRNA 519743..519826
/locus_tag="tL(UAA)D"
/product="tRNA-Leu"
/note="Leucine tRNA (tRNA-Leu), predicted by tRNAscan-SE
analysis"
/db_xref="SGD:S000006649"
/db_xref="GeneID:851601"
LTR complement(520173..520475)
/note="Ty1 LTR"
/db_xref="SGD:S000006848"
LTR 520477..520805
/note="Ty1 LTR"
/db_xref="SGD:S000006863"
gene complement(520516..520692)
/locus_tag="YDR034C-A"
/db_xref="GeneID:851602"
mRNA complement(520516..520692)
/locus_tag="YDR034C-A"
/product="hypothetical protein"
/transcript_id="NM_001184326.1"
/db_xref="GI:296143389"
/db_xref="GeneID:851602"
CDS complement(520516..520692)
/locus_tag="YDR034C-A"
/note="hypothetical protein; contained within the solo Ty1
LTR element YDRWdelta7"
/codon_start=1
/product="hypothetical protein"
/protein_id="NP_010318.1"
/db_xref="GI:6320238"
/db_xref="SGD:S000007233"
/db_xref="GeneID:851602"
/translation="MESIFLHANITIIPHSVLYVSLSYYIINPCVSVSTNLDDYFSSF
VSSSNTVYDNILVT"
LTR complement(520806..520833)
/note="Ty1 LTR"
/db_xref="SGD:S000006849"
gene 520972..521043
/locus_tag="tQ(UUG)D1"
/db_xref="GeneID:851603"
tRNA 520972..521043
/locus_tag="tQ(UUG)D1"
/product="tRNA-Gln"
/note="Glutamine tRNA (tRNA-Gln), predicted by tRNAscan-SE
analysis; thiolation of uridine at wobble position (34)
requires Ncs6p"
/db_xref="SGD:S000006693"
/db_xref="GeneID:851603"
gene 521314..521469
/locus_tag="YDR034W-B"
/db_xref="GeneID:851604"
mRNA 521314..521469
/locus_tag="YDR034W-B"
/product="hypothetical protein"
/transcript_id="NM_001184327.3"
/db_xref="GI:398365164"
/db_xref="GeneID:851604"
CDS 521314..521469
/locus_tag="YDR034W-B"
/note="Predicted tail-anchored plasma membrane protein
containing a conserved CYSTM module; related proteins in
other organisms may be involved in response to stress;
green fluorescent protein (GFP)-fusion protein localizes
to the cell periphery"
/codon_start=1
/product="hypothetical protein"
/protein_id="NP_010319.3"
/db_xref="GI:398365165"
/db_xref="SGD:S000007234"
/db_xref="GeneID:851604"
/translation="MRHHQNMHYAPQQQPVYVQQPPPRRESGGCCRTCCHFLCCLCLI
NLCCDVF"
gene 521816..522928
/gene="ARO3"
/locus_tag="YDR035W"
/db_xref="GeneID:851605"
mRNA 521816..522928
/gene="ARO3"
/locus_tag="YDR035W"
/product="3-deoxy-7-phosphoheptulonate synthase ARO3"
/transcript_id="NM_001180343.3"
/db_xref="GI:398365166"
/db_xref="GeneID:851605"
CDS 521816..522928
/gene="ARO3"
/locus_tag="YDR035W"
/EC_number="2.5.1.54"
/note="3-deoxy-D-arabino-heptulosonate-7-phosphate (DAHP)
synthase, catalyzes the first step in aromatic amino acid
biosynthesis and is feedback-inhibited by phenylalanine or
high concentration of tyrosine or tryptophan"
/codon_start=1
/product="3-deoxy-7-phosphoheptulonate synthase ARO3"
/protein_id="NP_010320.3"
/db_xref="GI:398365167"
/db_xref="SGD:S000002442"
/db_xref="GeneID:851605"
/translation="MFIKNDHAGDRKRLEDWRIKGYDPLTPPDLLQHEFPISAKGEEN
IIKARDSVCDILNGKDDRLVIVIGPCSLHDPKAAYDYADRLAKISEKLSKDLLIIMRA
YLEKPRTTVGWKGLINDPDMNNSFQINKGLRISREMFIKLVEKLPIAGEMLDTISPQF
LSDCFSLGAIGARTTESQLHRELASGLSFPIGFKNGTDGGLQVAIDAMRAAAHEHYFL
SVTKPGVTAIVGTEGNKDTFLILRGGKNGTNFDKESVQNTKKQLEKAGLTDDSQKRIM
IDCSHGNSNKDFKNQPKVAKCIYDQLTEGENSLCGVMIESNINEGRQDIPKEGGREGL
KYGCSVTDACIGWESTEQVLELLAEGVRNRRKALKK"
gene complement(523211..524713)
/gene="EHD3"
/locus_tag="YDR036C"
/db_xref="GeneID:851606"
mRNA complement(523211..524713)
/gene="EHD3"
/locus_tag="YDR036C"
/product="Ehd3p"
/transcript_id="NM_001180344.1"
/db_xref="GI:296143392"
/db_xref="GeneID:851606"
CDS complement(523211..524713)
/gene="EHD3"
/locus_tag="YDR036C"
/note="3-hydroxyisobutyryl-CoA hydrolase, member of a
family of enoyl-CoA hydratase/isomerases; non-tagged
protein is detected in highly purified mitochondria in
high-throughput studies; phosphorylated; mutation affects
fluid-phase endocytosis"
/codon_start=1
/product="Ehd3p"
/protein_id="NP_010321.1"
/db_xref="GI:6320241"
/db_xref="SGD:S000002443"
/db_xref="GeneID:851606"
/translation="MLRNTLKCAQLSSKYGFKTTTRTFMTTQPQLNVTDAPPVLFTVQ
DTARVITLNRPKKLNALNAEMSESMFKTLNEYAKSDTTNLVILKSSNRPRSFCAGGDV
ATVAIFNFNKEFAKSIKFFTDEYSLNFQIATYLKPIVTFMDGITMGGGVGLSIHTPFR
IATENTKWAMPEMDIGFFPDVGSTFALPRIVTLANSNSQMALYLCLTGEVVTGADAYM
LGLASHYVSSENLDALQKRLGEISPPFNNDPQSAYFFGMVNESIDEFVSPLPKDYVFK
YSNEKLNVIEACFNLSKNGTIEDIMNNLRQYEGSAEGKAFAQEIKTKLLTKSPSSLQI
ALRLVQENSRDHIESAIKRDLYTAANMCMNQDSLVEFSEATKHKLIDKQRVPYPWTKK
EQLFVSQLTSITSPKPSLPMSLLRNTSNVTWTQYPYHSKYQLPTEQEIAAYIEKRTND
DTGAKVTEREVLNHFANVIPSRRGKLGIQSLCKIVCERKCEEVNDGLRWK"
gene 525440..527215
/gene="KRS1"
/locus_tag="YDR037W"
/gene_synonym="GCD5"
/db_xref="GeneID:851607"
mRNA 525440..527215
/gene="KRS1"
/locus_tag="YDR037W"
/gene_synonym="GCD5"
/product="lysine--tRNA ligase KRS1"
/transcript_id="NM_001180345.1"
/db_xref="GI:296143393"
/db_xref="GeneID:851607"
CDS 525440..527215
/gene="KRS1"
/locus_tag="YDR037W"
/gene_synonym="GCD5"
/EC_number="6.1.1.6"
/note="Lysyl-tRNA synthetase"
/codon_start=1
/product="lysine--tRNA ligase KRS1"
/protein_id="NP_010322.1"
/db_xref="GI:6320242"
/db_xref="SGD:S000002444"
/db_xref="GeneID:851607"
/translation="MSQQDNVKAAAEGVANLHLDEATGEMVSKSELKKRIKQRQVEAK
KAAKKAAAQPKPASKKKTDLFADLDPSQYFETRSRQIQELRKTHEPNPYPHKFHVSIS
NPEFLAKYAHLKKGETLPEEKVSIAGRIHAKRESGSKLKFYVLHGDGVEVQLMSQLQD
YCDPDSYEKDHDLLKRGDIVGVEGYVGRTQPKKGGEGEVSVFVSRVQLLTPCLHMLPA
DHFGFKDQETRYRKRYLDLIMNKDARNRFITRSEIIRYIRRFLDQRKFIEVETPMMNV
IAGGATAKPFITHHNDLDMDMYMRIAPELFLKQLVVGGLDRVYEIGRQFRNEGIDMTH
NPEFTTCEFYQAYADVYDLMDMTELMFSEMVKEITGSYIIKYHPDPADPAKELELNFS
RPWKRINMIEELEKVFNVKFPSGDQLHTAETGEFLKKILVDNKLECPPPLTNARMLDK
LVGELEDTCINPTFIFGHPQMMSPLAKYSRDQPGLCERFEVFVATKEICNAYTELNDP
FDQRARFEEQARQKDQGDDEAQLVDETFCNALEYGLPPTGGWGCGIDRLAMFLTDSNT
IREVLLFPTLKPDVLREEVKKEEEN"
gene complement(527422..530697)
/gene="ENA5"
/locus_tag="YDR038C"
/db_xref="GeneID:851608"
mRNA complement(527422..530697)
/gene="ENA5"
/locus_tag="YDR038C"
/product="putative Na(+)-exporting P-type ATPase ENA5"
/transcript_id="NM_001180346.3"
/db_xref="GI:398365196"
/db_xref="GeneID:851608"
CDS complement(527422..530697)
/gene="ENA5"
/locus_tag="YDR038C"
/EC_number="3.6.3.7"
/note="Protein with similarity to P-type ATPase sodium
pumps, member of the Na+ efflux ATPase family"
/codon_start=1
/product="putative Na(+)-exporting P-type ATPase ENA5"
/protein_id="NP_010323.3"
/db_xref="GI:398365197"
/db_xref="SGD:S000002445"
/db_xref="GeneID:851608"
/translation="MSEGTVKENNNEEFNAYHTLTTEEAAEFIGTSLTEGLTQDESLR
RLKAVGENTLGDDTKIDYKAMVLHQVCNAMIMVLVISMAISFAVRDWITGGVISFVIA
VNVLIGLVQEYKATKTMNSLKNLSSPNAHVIRNGKSETINSKDVVPGDICLVKVGDTI
PADLRLIETKNFDTDESLLTGESLPVSKDANLVFGKEEETSVGDRLNLAFSSSAVVKG
RAKGIVIKTALNSEIGKIAKSLQGDSGLISRDPSKSWLQNTWISTKKVTGAFLGTNVG
TPLHRKLSKLAVLLFWIAVLFAIIVMASQKFDVDKRVAIYAICVALSMIPSSLVVVLT
ITMSVGAAVMVSRNVIVRKLDSLEALGAVNDICSDKTGTLTQGKMLARQIWIPRFGTI
TISNSDDPFNPNEGNVSLIPRFSPYEYSHNEDGDVGILQNFKDRLYEKDLPEDIDMDL
FQKWLETATLANIATVFKDDATDCWKAHGDPTEIAIQVFATKMDLPHNALTGEKSTNQ
SNENDQSSLSQHNEKPGSAQFEHIAEFPFDSTVKRMSSVYYNNHNETYNIYGKGAFES
IISCCSSWYGKDGVKITPLTDCDVETIRKNVYSLSNEGLRVLGFASKSFTKDQVNDDQ
LKNITSNRATAESDLVFLGLIGIYDPPRNETAGAVKKFHQAGINVHMLTGDFVGTAKA
IAQEVGILPTNLYHYSQEIVDSMVMTGSQFDGLSEEEVDDLPVLPLVIARCSPQTKVR
MIEALHRRKKFCAMTGDGVNDSPSLKMANVGIAMGINGSDVSKEASDIVLSDDNFASI
LNAVEEGRRMTDNIQKFVLQLLAENVAQALYLIIGLVFRDENGKSVFPLSPVEVLWII
VVTSCFPAMGLGLEKAAPDLMDRPPNDSEVGIFTWEVIIDTFAYGIIMTGSCMASFTG
SLYGINSGRLGHDCDGTYNSSCRDVYRSRSAAFATMTWCALILAWEVVDMRRSFFRMH
PDTDSPVKEFFRSIWGNQFLFWSIIFGFVSAFPVVYIPVINDKVFLHKPIGAEWGLAI
AFTIAFWIGAELYKCGKRRYFKTQRAHNSENDLERSSKHDPFEAYSTSTTLQSEINIS
VKH"
gene complement(531307..534582)
/gene="ENA2"
/locus_tag="YDR039C"
/db_xref="GeneID:851609"
mRNA complement(531307..534582)
/gene="ENA2"
/locus_tag="YDR039C"
/product="Na(+)-exporting P-type ATPase ENA2"
/transcript_id="NM_001180347.3"
/db_xref="GI:398365206"
/db_xref="GeneID:851609"
CDS complement(531307..534582)
/gene="ENA2"
/locus_tag="YDR039C"
/EC_number="3.6.3.12"
/EC_number="3.6.3.7"
/note="P-type ATPase sodium pump, involved in Na+ efflux
to allow salt tolerance; likely not involved in Li+
efflux"
/codon_start=1
/product="Na(+)-exporting P-type ATPase ENA2"
/protein_id="NP_010324.3"
/db_xref="GI:398365207"
/db_xref="SGD:S000002446"
/db_xref="GeneID:851609"
/translation="MSEGTVKENNNEEFNAYHTLTTEEAAEFIGTSLTEGLTQDESLR
RLKAVGENTLGDDTKIDYKAMVLHQVCNAMIMVLVISMAISFAVRDWITGGVISFVIA
VNVLIGLVQEYKATKTMNSLKNLSSPNAHVIRNGKSETINSKDVVPGDICLVKVGDTI
PADLRLIETKNFDTDESLLTGESLPVSKDANLVFGKEEETSVGDRLNLAFSSSAVVKG
RAKGIVIKTALNSEIGKIAKSLQGDSGLISRDPSKSWLQNTWISTKKVTGAFLGTNVG
TPLHRKLSKLAVLLFWIAVLFAIIVMASQKFDVDKRVAIYAICVALSMIPSSLVVVLT
ITMSVGAAVMVSRNVIVRKLDSLEALGAVNDICSDKTGTLTQGKMLARQIWIPRFGTI
TISNSDDPFNPNEGNVSLIPRFSPYEYSHNEDGDVGILQNFKDRLYEKDLPEDIDMDL
FQKWLETATLANIATVFKDDATDCWKAHGDPTEIAIQVFATKMDLPHNALTGEKSTNQ
SNENDQSSLSQHNEKPGSAQFEHIAEFPFDSTVKRMSSVYYNNHNETYNIYGKGAFES
IISCCSSWYGKDGVKITPLTDCDVETIRKNVYSLSNEGLRVLGFASKSFTKDQVNDDQ
LKNITSNRATAESDLVFLGLIGIYDPPRNETAGAVKKFHQAGINVHMLTGDFVGTAKA
IAQEVGILPTNLYHYSQEIVDSMVMTGSQFDGLSEEEVDDLPVLPLVIARCSPQTKVR
MIEALHRRKKFCAMTGDGVNDSPSLKMANVGIAMGINGSDVSKEASDIVLSDDNFASI
LNAVEEGRRMTDNIQKFVLQLLAENVAQALYLIIGLVFRDENGKSVFPLSPVEVLWII
VVTSCFPAMGLGLEKAAPDLMDRPPHDSEVGIFTWEVIIDTFAYGIIMTGSCMASFTG
SLYGINSGRLGHDCDGTYNSSCRDVYRSRSAAFATMTWCALILAWEVVDMRRSFFRMH
PDTDSPVKEFFRSIWGNQFLFWSIIFGFVSAFPVVYIPVINDKVFLHKPIGAEWGLAI
AFTIAFWIGAELYKCGKRRYFKTQRAHNPENDLESNNKRDPFEAYSTSTTIHTEVNIG
IKQ"
gene complement(535192..538467)
/gene="ENA1"
/locus_tag="YDR040C"
/gene_synonym="HOR6; PMR2"
/db_xref="GeneID:851610"
mRNA complement(535192..538467)
/gene="ENA1"
/locus_tag="YDR040C"
/gene_synonym="HOR6; PMR2"
/product="Na(+)/Li(+)-exporting P-type ATPase ENA1"
/transcript_id="NM_001180348.1"
/db_xref="GI:296143396"
/db_xref="GeneID:851610"
CDS complement(535192..538467)
/gene="ENA1"
/locus_tag="YDR040C"
/gene_synonym="HOR6; PMR2"
/EC_number="3.6.3.7"
/note="P-type ATPase sodium pump, involved in Na+ and Li+
efflux to allow salt tolerance"
/codon_start=1
/product="Na(+)/Li(+)-exporting P-type ATPase ENA1"
/protein_id="NP_010325.1"
/db_xref="GI:6320245"
/db_xref="SGD:S000002447"
/db_xref="GeneID:851610"
/translation="MGEGTTKENNNAEFNAYHTLTAEEAAEFIGTSLTEGLTQDEFVH
RLKTVGENTLGDDTKIDYKAMVLHQVCNAMIMVLLISMIISFAMHDWITGGVISFVIA
VNVLIGLVQEYKATKTMNSLKNLSSPNAHVIRNGKSETINSKDVVPGDICLVKVGDTI
PADLRLIETKNFDTDESLLTGESLPVSKDANLVFGKEEETSVGDRLNLAFSSSAVVKG
RAKGIVIKTALNSEIGKIAKSLQGDSGLISRDPSKSWLQNTWISTKKVTGAFLGTNVG
TPLHRKLSKLAVLLFWIAVLFAIIVMASQKFDVDKRVAIYAICVALSMIPSSLVVVLT
ITMSVGAAVMVSRNVIVRKLDSLEALGAVNDICSDKTGTLTQGKMLARQIWIPRFGTI
TISNSDDPFNPNEGNVSLIPRFSPYEYSHNEDGDVGILQNFKDRLYEKDLPEDIDMDL
FQKWLETATLANIATVFKDDATDCWKAHGDPTEIAIQVFATKMDLPHNALTGEKSTNQ
SNENDQSSLSQHNEKPGSAQFEHIAEFPFDSTVKRMSSVYYNNHNETYNIYGKGAFES
IISCCSSWYGKDGVKITPLTDCDVETIRKNVYSLSNEGLRVLGFASKSFTKDQVNDDQ
LKNITSNRATAESDLVFLGLIGIYDPPRNETAGAVKKFHQAGINVHMLTGDFVGTAKA
IAQEVGILPTNLYHYSQEIVDSMVMTGSQFDGLSEEEVDDLPVLPLVIARCSPQTKVR
MIEALHRRKKFCTMTGDGVNDSPSLKMANVGIAMGINGSDVSKEASDIVLSDDNFASI
LNAVEEGRRMTDNIQKFVLQLLAENVAQALYLIIGLVFRDENGKSVFPLSPVEVLWII
VVTSCFPAMGLGLEKAAPDLMDRPPHDSEVGIFTWEVIIDTFAYGIIMTGSCMASFTG
SLYGINSGRLGHDCDGTYNSSCRDVYRSRSAAFATMTWCALILAWEVVDMRRSFFRMH
PDTDSPVKEFFRSIWGNQFLFWSIIFGFVSAFPVVYIPVINDKVFLHKPIGAEWGLAI
AFTIAFWIGAELYKCGKRRYFKTQRAHNPENDLESNNKRDPFEAYSTSTTIHTEVNIG
IKQ"
gene 539803..540414
/gene="RSM10"
/locus_tag="YDR041W"
/db_xref="GeneID:851611"
mRNA 539803..540414
/gene="RSM10"
/locus_tag="YDR041W"
/product="mitochondrial 37S ribosomal protein RSM10"
/transcript_id="NM_001180349.1"
/db_xref="GI:296143397"
/db_xref="GeneID:851611"
CDS 539803..540414
/gene="RSM10"
/locus_tag="YDR041W"
/note="Mitochondrial ribosomal protein of the small
subunit, has similarity to E. coli S10 ribosomal protein;
essential for viability, unlike most other mitoribosomal
proteins"
/codon_start=1
/product="mitochondrial 37S ribosomal protein RSM10"
/protein_id="NP_010326.1"
/db_xref="GI:6320246"
/db_xref="SGD:S000002448"
/db_xref="GeneID:851611"
/translation="MLRNTIALRSFIRTQSTRPYPVNVEAVYYAPLKLPIKYGDLVAD
IQLRSYDNENLDFYSDFILRTGYYLGIPLTGPKPLPTRRERWTVIKSPFVHAKSKENF
ERHTHKRLIRAWDTNPEVLQMLIAYITKHSMAGVGMKCNFFQRSEISLDLGSDANGLE
KSLSNIDELYSLRNDDKAQTSAVGQKVLELLDSPDFKKHLEKK"
gene complement(540601..541203)
/locus_tag="YDR042C"
/db_xref="GeneID:851612"
mRNA complement(540601..541203)
/locus_tag="YDR042C"
/product="hypothetical protein"
/transcript_id="NM_001180350.3"
/db_xref="GI:398365226"
/db_xref="GeneID:851612"
CDS complement(540601..541203)
/locus_tag="YDR042C"
/note="hypothetical protein; expression is increased in
ssu72-ts69 mutant"
/codon_start=1
/product="hypothetical protein"
/protein_id="NP_010327.3"
/db_xref="GI:398365227"
/db_xref="SGD:S000002449"
/db_xref="GeneID:851612"
/translation="MEQILYNQSLKISTLSTFQGLKFLKVLIFSIFQQLFYNPVIQLF
GTKASIMESDSTTLLESSWSTERNFLNMNSDSISATKNVFILFFTIFRLAEYIVYKLS
DQKYRLHTSLNVQHFRWNSKKNTNRKRTLSFSKAYLPRTNILPIFVADGLKNRFSGPL
PGKSLESFQKLNLLSDNNIKRYAVPGNKAVNTLLWQEQYS"
gene complement(541602..541700)
/locus_tag="snR47"
/db_xref="GeneID:9164877"
ncRNA complement(541602..541700)
/locus_tag="snR47"
/ncRNA_class="snoRNA"
/product="SNR47"
/note="C/D box small nucleolar RNA (snoRNA), guides
2'-O-methylation of large subunit (LSU) rRNA at position
A2220 and small subunit (SSU) rRNA at position A619"
/db_xref="SGD:S000006507"
/db_xref="GeneID:9164877"
gene complement(542674..543369)
/gene="NRG1"
/locus_tag="YDR043C"
/db_xref="GeneID:851613"
mRNA complement(542674..543369)
/gene="NRG1"
/locus_tag="YDR043C"
/product="Nrg1p"
/transcript_id="NM_001180351.3"
/db_xref="GI:398365236"
/db_xref="GeneID:851613"
CDS complement(542674..543369)
/gene="NRG1"
/locus_tag="YDR043C"
/note="Transcriptional repressor; recruits the Cyc8p-Tup1p
complex to promoters; mediates glucose repression and
negatively regulates a variety of processes including
filamentous growth and alkaline pH response; NRG1 has a
paralog, NRG2, that arose from the whole genome
duplication"
/codon_start=1
/product="Nrg1p"
/protein_id="NP_010328.3"
/db_xref="GI:398365237"
/db_xref="SGD:S000002450"
/db_xref="GeneID:851613"
/translation="MFYPYNYSNLNVSTMPALPGISAFDGMQDEENVEISPERKYQTL
LPVLTNSHVVENELKHKLNKTAFDFRYQTKSENGSEKWEPKYLITPNLQTRSVSFDNS
SVQYNSDSSEKSSLSQLTCNSSIIQQPENGIVSNDAYNKMANSRYSLKTRKQRTDPRN
TLSDEEDLEQRRKYICKICARGFTTSGHLARHNRIHTGEKNHCCPYKGCTQRFSRHDN
CLQHYRTHLKKGQ"
gene 546642..547628
/gene="HEM13"
/locus_tag="YDR044W"
/db_xref="GeneID:851614"
mRNA 546642..547628
/gene="HEM13"
/locus_tag="YDR044W"
/product="coproporphyrinogen oxidase"
/transcript_id="NM_001180352.1"
/db_xref="GI:296143400"
/db_xref="GeneID:851614"
CDS 546642..547628
/gene="HEM13"
/locus_tag="YDR044W"
/EC_number="1.3.3.3"
/note="Coproporphyrinogen III oxidase, an oxygen requiring
enzyme that catalyzes the sixth step in the heme
biosynthetic pathway; transcription is repressed by oxygen
and heme (via Rox1p and Hap1p)"
/codon_start=1
/product="coproporphyrinogen oxidase"
/protein_id="NP_010329.1"
/db_xref="GI:6320249"
/db_xref="SGD:S000002451"
/db_xref="GeneID:851614"
/translation="MPAPQDPRNLPIRQQMEALIRRKQAEITQGLESIDTVKFHADTW
TRGNDGGGGTSMVIQDGTTFEKGGVNVSVVYGQLSPAAVSAMKADHKNLRLPEDPKTG
LPVTDGVKFFACGLSMVIHPVNPHAPTTHLNYRYFETWNQDGTPQTWWFGGGADLTPS
YLYEEDGQLFHQLHKDALDKHDTALYPRFKKWCDEYFYITHRKETRGIGGIFFDDYDE
RDPQEILKMVEDCFDAFLPSYLTIVKRRKDMPYTKEEQQWQAIRRGRYVEFNLIYDRG
TQFGLRTPGSRVESILMSLPEHASWLYNHHPAPGSREAKLLEVTTKPREWVK"
gene complement(547978..548310)
/gene="RPC11"
/locus_tag="YDR045C"
/db_xref="GeneID:851615"
mRNA complement(547978..548310)
/gene="RPC11"
/locus_tag="YDR045C"
/product="Rpc11p"
/transcript_id="NM_001180353.1"
/db_xref="GI:296143401"
/db_xref="GeneID:851615"
CDS complement(547978..548310)
/gene="RPC11"
/locus_tag="YDR045C"
/note="RNA polymerase III subunit C11; mediates pol III
RNA cleavage activity and is important for termination of
transcription; homologous to TFIIS"
/codon_start=1
/product="Rpc11p"
/protein_id="NP_010330.1"
/db_xref="GI:6320250"
/db_xref="SGD:S000002452"
/db_xref="GeneID:851615"
/translation="MLSFCPSCNNMLLITSGDSGVYTLACRSCPYEFPIEGIEIYDRK
KLPRKEVDDVLGGGWDNVDQTKTQCPNYDTCGGESAYFFQLQIRSADEPMTTFYKCVN
CGHRWKEN"
gene complement(548762..550576)
/gene="BAP3"
/locus_tag="YDR046C"
/gene_synonym="PAP1"
/db_xref="GeneID:851616"
mRNA complement(548762..550576)
/gene="BAP3"
/locus_tag="YDR046C"
/gene_synonym="PAP1"
/product="Bap3p"
/transcript_id="NM_001180354.3"
/db_xref="GI:398365248"
/db_xref="GeneID:851616"
CDS complement(548762..550576)
/gene="BAP3"
/locus_tag="YDR046C"
/gene_synonym="PAP1"
/note="Amino acid permease involved in the uptake of
cysteine, leucine, isoleucine and valine"
/codon_start=1
/product="Bap3p"
/protein_id="NP_010331.3"
/db_xref="GI:398365249"
/db_xref="SGD:S000002453"
/db_xref="GeneID:851616"
/translation="MSDPIVTSSKMEKSAEFEVTDSALYNNFNTSTTASLTPEIKEHS
EESRNGLVHRFVDSFRRAESQRLEEDNDLEDGTKSMKSNNHLKKSMKSRHVVMMSLGT
GIGTGLLVANAKGLSLAGPGSLVIGYVMVSFVTYFMVQAAGEMGVTYPTLPGNFNAYN
SIFISKSFGFATTWLFCIQWLTVLPLELITSSMTVKYWNDTINADVFIVIFYVFLLFI
HFFGVKAYGETEFIFNSCKILMVAGFIILSVVINCGGAGVDGYIGGKYWRDPGSFAEG
SGATRFKGICYILVSAYFSFGGIELFVLSINEQSNPRKSTPVAAKRSVYRILIIYLLT
MILIGFNVPHNNDQLMGSGGSATHASPYVLAASIHKVRVIPHIINAVILISVISVANS
ALYAAPRLMCSLAQQGYAPKFLNYIDREGRPLRALVVCSLVGVVGFVACSPQEEQAFT
WLAAIAGLSELFTWSGIMLSHIRFRKAMKVQGRSLDEVGYKANTGIWGSYYGVFFNML
VFMAQFWVALSPIGNGGKCDAQAFFESYLAAPLWIFMYVGYMVYKRDFTFLNPLDKID
LDFHRRVYDPEIMRQEDEENKERLKNSSIFVRVYKFWC"
gene 551860..552948
/gene="HEM12"
/locus_tag="YDR047W"
/gene_synonym="HEM6"
/db_xref="GeneID:851617"
mRNA 551860..552948
/gene="HEM12"
/locus_tag="YDR047W"
/gene_synonym="HEM6"
/product="uroporphyrinogen decarboxylase HEM12"
/transcript_id="NM_001180355.3"
/db_xref="GI:398365256"
/db_xref="GeneID:851617"
CDS 551860..552948
/gene="HEM12"
/locus_tag="YDR047W"
/gene_synonym="HEM6"
/EC_number="4.1.1.37"
/note="Uroporphyrinogen decarboxylase, catalyzes the fifth
step in the heme biosynthetic pathway; localizes to both
the cytoplasm and nucleus; a hem12 mutant has phenotypes
similar to patients with porphyria cutanea tarda"
/codon_start=1
/product="uroporphyrinogen decarboxylase HEM12"
/protein_id="NP_010332.3"
/db_xref="GI:398365257"
/db_xref="SGD:S000002454"
/db_xref="GeneID:851617"
/translation="MGNFPAPKNDLILRAAKGEKVERPPCWIMRQAGRYLPEYHEVKN
NRDFFQTCRDAEIASEITIQPVRRYRGLIDAAIIFSDILVIPQAMGMRVEMLEGKGPH
FPEPLRNPEDLQTVLDYKVDVLKELDWAFKAITMTRIKLDGEVPLFGFCGGPWTLMVY
MTEGGGSRLFRFAKQWINMYPELSHKLLQKITDVAVEFLSQQVVAGAQILQVFESWGG
ELSSVDFDEFSLPYLRQIAERVPKRLQELGIMEQIPMIVFAKGSWYALDKLCCSGFDV
VSLDWSWDPREAVKINKNRVTLQGNLDPGVMYGSKEVITKKVKQMIEAFGGGKSRYIV
NFGHGTHPFMDPDVIKFFLEECHRIGSK"
gene 553254..555152
/gene="VMS1"
/locus_tag="YDR049W"
/db_xref="GeneID:851618"
mRNA 553254..555152
/gene="VMS1"
/locus_tag="YDR049W"
/product="Vms1p"
/transcript_id="NM_001180357.1"
/db_xref="GI:296143404"
/db_xref="GeneID:851618"
CDS 553254..555152
/gene="VMS1"
/locus_tag="YDR049W"
/note="Component of a Cdc48p-complex involved in protein
quality control; exhibits cytosolic and ER-membrane
localization, with Cdc48p, during normal growth, and
contributes to ER-associated degradation (ERAD) of
specific substrates at a step after their ubiquitination;
forms a mitochondrially-associated complex with Cdc48p and
Npl4p under oxidative stress that is required for
ubiquitin-mediated mitochondria-associated protein
degradation (MAD); conserved in C. elegans and humans"
/codon_start=1
/product="Vms1p"
/protein_id="NP_010334.1"
/db_xref="GI:6320253"
/db_xref="SGD:S000002456"
/db_xref="GeneID:851618"
/translation="MNSQKASKMTGSLKKNDLYIFDLSEQLLNSLKLMSFDSTLREVE
VEKTSDNDRNKESGDLQIARKKVTSNVMRCSVCQMSFDSRNEQKAHYQTDYHLMNVKR
NLRGLDILSVEEFDALISKEHGIKSEDENSGGEQTSSDHEESEEASDRDPDLQTNNYM
ETIIENDLQKLGFQKDESDAISHINTQSPYIYFKSKYLQKNEVLAIYKSLFNKRSLSN
PNEALTFWNSQENPMAISALFMVGGGHFAGAIVSHQRLNVKGNAHKKDETLIEQAVNF
LEHKTFHRYTTRRKQGGSQSAMDNAKGKANSAGSALRRYNESALKTDIQGVLKDWEPY
LSKCDNIFIRARNVSDKKIFTDNTVLNKGDERIKSFPFTTNRPTVLELKKAWCELSYL
KILPKPEPLAVKETVQKLEVSNKKDEFKEKQEPLLEEIQTEEIISLLKKGRAPLLISF
LKKNKLDGNFRLKPESKYSLTPTMLHYASQQGMKQMALILLSNIKCDPTIKNRLGRTA
WDLNRNDDVRHAFQIARYNLGESFTNWDETHIGQPLSREQVDEINEKKKAIENEKAEK
LIKLELEAAKEKQRFAKDAERGPGKKLTNIPSIQQQNLNSLTDEQRRRLMREQRARAA
EERMKKKY"
STS 554268..554494
/gene="VMS1"
/locus_tag="YDR049W"
/standard_name="px-6e8"
/db_xref="UniSTS:258142"
rep_origin 555230..555466
/note="ARS418;
Autonomously Replicating Sequence"
/db_xref="SGD:S000118435"
gene complement(555726..556472)
/gene="TPI1"
/locus_tag="YDR050C"
/db_xref="GeneID:851620"
mRNA complement(555726..556472)
/gene="TPI1"
/locus_tag="YDR050C"
/product="triose-phosphate isomerase TPI1"
/transcript_id="NM_001180358.1"
/db_xref="GI:296143405"
/db_xref="GeneID:851620"
CDS complement(555726..556472)
/gene="TPI1"
/locus_tag="YDR050C"
/EC_number="5.3.1.1"
/note="Triose phosphate isomerase, abundant glycolytic
enzyme; mRNA half-life is regulated by iron availability;
transcription is controlled by activators Reb1p, Gcr1p,
and Rap1p through binding sites in the 5' non-coding
region; inhibition of Tpi1p activity by PEP
(phosphoenolpyruvate) stimulates redox metabolism in
respiring cells; E104D mutation in human TPI causes a rare
autosomal disease"
/codon_start=1
/product="triose-phosphate isomerase TPI1"
/protein_id="NP_010335.1"
/db_xref="GI:6320255"
/db_xref="SGD:S000002457"
/db_xref="GeneID:851620"
/translation="MARTFFVGGNFKLNGSKQSIKEIVERLNTASIPENVEVVICPPA
TYLDYSVSLVKKPQVTVGAQNAYLKASGAFTGENSVDQIKDVGAKWVILGHSERRSYF
HEDDKFIADKTKFALGQGVGVILCIGETLEEKKAGKTLDVVERQLNAVLEEVKDWTNV
VVAYEPVWAIGTGLAATPEDAQDIHASIRKFLASKLGDKAASELRILYGGSANGSNAV
TFKDKADVDGFLVGGASLKPEFVDIINSRN"
gene complement(557056..558060)
/gene="DET1"
/locus_tag="YDR051C"
/db_xref="GeneID:851621"
mRNA complement(557056..558060)
/gene="DET1"
/locus_tag="YDR051C"
/product="Det1p"
/transcript_id="NM_001180359.3"
/db_xref="GI:398365272"
/db_xref="GeneID:851621"
CDS complement(557056..558060)
/gene="DET1"
/locus_tag="YDR051C"
/EC_number="5.4.2.1"
/note="Acid phosphatase involved in the non-vesicular
transport of sterols in both directions between the
endoplasmic reticulum and plasma membrane; deletion
confers sensitivity to nickel"
/codon_start=1
/product="Det1p"
/protein_id="NP_010336.3"
/db_xref="GI:398365273"
/db_xref="SGD:S000002458"
/db_xref="GeneID:851621"
/translation="MCEENVHVSEDVAGSHGSFTNARPRLIVLIRHGESESNKNKEVN
GYIPNHLISLTKTGQIQARQAGIDLLRVLNVDDHNLVEDLAKKYIKDESSRRTLPLKD
YTRLSREKDTNIVFYTSPYRRARETLKGILDVIDEYNELNSGVRICEDMRYDPHGKQK
HAFWPRGLNNTGGVYENNEDNICEGKPGKCYLQYRVKDEPRIREQDFGNFQKINSMQD
VMKKRSTYGHFFFRFPHGESAADVYDRVASFQETLFRHFHDRQERRPRDVVVLVTHGI
YSRVFLMKWFRWTYEEFESFTNVPNGSVMVMELDESINRYVLRTVLPKWTDCEGDLTT
"
gene complement(558511..560625)
/gene="DBF4"
/locus_tag="YDR052C"
/gene_synonym="DNA52; LSD7"
/db_xref="GeneID:851623"
mRNA complement(558511..560625)
/gene="DBF4"
/locus_tag="YDR052C"
/gene_synonym="DNA52; LSD7"
/product="Dbf4p"
/transcript_id="NM_001180360.3"
/db_xref="GI:398365276"
/db_xref="GeneID:851623"
CDS complement(558511..560625)
/gene="DBF4"
/locus_tag="YDR052C"
/gene_synonym="DNA52; LSD7"
/note="Regulatory subunit of Cdc7p-Dbf4p kinase complex;
required for Cdc7p kinase activity and initiation of DNA
replication; phosphorylates the Mcm2-7 family of proteins;
cell cycle regulated; relative distribution to the nucleus
increases upon DNA replication stress"
/codon_start=1
/product="Dbf4p"
/protein_id="NP_010337.3"
/db_xref="GI:398365277"
/db_xref="SGD:S000002459"
/db_xref="GeneID:851623"
/translation="MVSPTKMIIRSPLKETDTNLKHNNGIAASTTAAGHLNVFSNDNN
CNNNNTTESFPKKRSLERLELQQQQHLHEKKRARIERARSIEGAVQVSKGTGLKNVEP
RVTPKELLEWQTNWKKIMKRDSRIYFDITDDVEMNTYNKSKMDKRRDLLKRGFLTLGA
QITQFFDTTVTIVITRRSVENIYLLKDTDILSRAKKNYMKVWSYEKAARFLKNLDVDL
DHLSKTKSASLAAPTLSNLLHNEKLYGPTDRDPRTKRDDIHYFKYPHVYLYDLWQTWA
PIITLEWKPQELTNLDELPYPILKIGSFGRCPFIGDRNYDESSYKRVVKRYSRDKANK
KYALQLRALFQYHADTLLNTSSVNDQTKNLIFIPHTCNDSTKSFKKWMQEKAKNFEKT
ELKKTDDSAVQDVRNEHADQTDEKNSILLNETETKEPPLKEEKENKQSIAEESNKYPQ
RKELAATPKLNHPVLATFARQETEEVPDDLCTLKTKSRQAFEIKASGAHQSNDVATSF
GNGLGPTRASVMSKNMKSLSRLMVDRKLGVKQTNGNNKNYTATIATTAETSKENRHRL
DFNALKKDEAPSKETGKDSAVHLETNRKPQNFPKVATKSVSADSKVHNDIKITTTESP
TASKKSTSTNVTLHFNAQTAQTAQPVKKETVKNSGYCENCRVKYESLEQHIVSEKHLS
FAENDLNFEAIDSLIENLRFQI"
gene complement(561440..562327)
/gene="CDC34"
/locus_tag="YDR054C"
/gene_synonym="DNA6; UBC3"
/db_xref="GeneID:851624"
mRNA complement(561440..562327)
/gene="CDC34"
/locus_tag="YDR054C"
/gene_synonym="DNA6; UBC3"
/product="SCF E2 ubiquitin-protein ligase catalytic
subunit CDC34"
/transcript_id="NM_001180362.1"
/db_xref="GI:296143408"
/db_xref="GeneID:851624"
CDS complement(561440..562327)
/gene="CDC34"
/locus_tag="YDR054C"
/gene_synonym="DNA6; UBC3"
/EC_number="6.3.2.19"
/note="Ubiquitin-conjugating enzyme (E2); catalytic
subunit of SCF ubiquitin-protein ligase complex (together
with Skp1p, Rbx1p, Cdc53p, and an F-box protein) that
regulates cell cycle progression by targeting key
substrates for degradation; protein abundance increases in
response to DNA replication stress"
/codon_start=1
/product="SCF E2 ubiquitin-protein ligase catalytic
subunit CDC34"
/protein_id="NP_010339.1"
/db_xref="GI:6320259"
/db_xref="SGD:S000002461"
/db_xref="GeneID:851624"
/translation="MSSRKSTASSLLLRQYRELTDPKKAIPSFHIELEDDSNIFTWNI
GVMVLNEDSIYHGGFFKAQMRFPEDFPFSPPQFRFTPAIYHPNVYRDGRLCISILHQS
GDPMTDEPDAETWSPVQTVESVLISIVSLLEDPNINSPANVDAAVDYRKNPEQYKQRV
KMEVERSKQDIPKGFIMPTSESAYISQSKLDEPESNKDMADNFWYDSDLDDDENGSVI
LQDDDYDDGNNHIPFEDDDVYNYNDNDDDDERIEFEDDDDDDDDSIDNDSVMDRKQPH
KAEDESEDVEDVERVSKKI"
gene 563527..564861
/gene="PST1"
/locus_tag="YDR055W"
/gene_synonym="HPF2"
/db_xref="GeneID:851625"
mRNA 563527..564861
/gene="PST1"
/locus_tag="YDR055W"
/gene_synonym="HPF2"
/product="Pst1p"
/transcript_id="NM_001180363.1"
/db_xref="GI:296143409"
/db_xref="GeneID:851625"
CDS 563527..564861
/gene="PST1"
/locus_tag="YDR055W"
/gene_synonym="HPF2"
/note="Cell wall protein that contains a putative
GPI-attachment site; secreted by regenerating protoplasts;
up-regulated by activation of the cell integrity pathway,
as mediated by Rlm1p; upregulated by cell wall damage via
disruption of FKS1"
/codon_start=1
/product="Pst1p"
/protein_id="NP_010340.1"
/db_xref="GI:6320260"
/db_xref="SGD:S000002462"
/db_xref="GeneID:851625"
/translation="MQLHSLIASTALLITSALAATSSSSSIPSSCTISSHATATAQSD
LDKYSRCDTLVGNLTIGGGLKTGALANVKEINGSLTIFNATNLTSFAADSLESITDSL
NLQSLTILTSASFGSLQSVDSIKLITLPAISSFTSNIKSANNIYISDTSLQSVDGFSA
LKKVNVFNVNNNKKLTSIKSPVETVSDSLQFSFNGNQTKITFDDLVWANNISLTDVHS
VSFANLQKINSSLGFINNSISSLNFTKLNTIGQTFSIVSNDYLKNLSFSNLSTIGGAL
VVANNTGLQKIGGLDNLTTIGGTLEVVGNFTSLNLDSLKSVKGGADVESKSSNFSCNA
LKALQKKGGIKGESFVCKNGASSTSVKLSSTSKSQSSQTTAKVSKSSSKAEEKKFTSG
DIKAAASASSVSSSGASSSSSKSSKGNAAIMAPIGQTTPLVGLLTAIIMSIM"
gene complement(565023..565640)
/locus_tag="YDR056C"
/db_xref="GeneID:851626"
mRNA complement(565023..565640)
/locus_tag="YDR056C"
/product="hypothetical protein"
/transcript_id="NM_001180364.3"
/db_xref="GI:398365294"
/db_xref="GeneID:851626"
CDS complement(565023..565640)
/locus_tag="YDR056C"
/note="hypothetical protein; green fluorescent protein
(GFP)-fusion protein localizes to the endoplasmic
reticulum; YDR056C is not an essential protein"
/codon_start=1
/product="hypothetical protein"
/protein_id="NP_010341.3"
/db_xref="GI:398365295"
/db_xref="SGD:S000002463"
/db_xref="GeneID:851626"
/translation="MLVRLLRVILLASMVFCADILQLSYSDDAKDAIPLGTFEIDSTS
DGNVTVTTVNIQDVEVSGEYCLNAQIEGKLDMPCFSYMKLRTPLKYDLIVDVDEDNEV
KQVSLSYDETNDAITATVRYPEAGPTAPVTKLKKKTKTYADKKASKNKDGSTAQFEED
EEVKEVSWFQKNWKMLLLGLLIYNFVAGSAKKQQQGGAGADQKTE"
gene 565927..567555
/gene="YOS9"
/locus_tag="YDR057W"
/db_xref="GeneID:851627"
mRNA 565927..567555
/gene="YOS9"
/locus_tag="YDR057W"
/product="Yos9p"
/transcript_id="NM_001180365.3"
/db_xref="GI:398365296"
/db_xref="GeneID:851627"
CDS 565927..567555
/gene="YOS9"
/locus_tag="YDR057W"
/note="ER quality-control lectin; integral subunit of the
HRD ligase; binds to glycans with terminal alpha-1,6
linked mannose on misfolded N-glycosylated proteins and
participates in targeting proteins to ERAD; member of the
OS-9 protein family"
/codon_start=1
/product="Yos9p"
/protein_id="NP_010342.3"
/db_xref="GI:398365297"
/db_xref="SGD:S000002464"
/db_xref="GeneID:851627"
/translation="MQAKIIYALSAISALIPLGSSLLAPIEDPIVSNKYLISYIDEDD
WSDRILQNQSVMNSGYIVNMGDDLECFIQNASTQLNDVLEDSNEHSNSEKTALLTKTL
NQGVKTIFDKLNERCIFYQAGFWIYEYCPGIEFVQFHGRVNTKTGEIVNRDESLVYRL
GKPKANVEEREFELLYDDVGYYISEIIGSGDICDVTGAERMVEIQYVCGGSNSGPSTI
QWVRETKICVYEAQVTIPELCNLELLAKNEDQKNASPILCRMPAKSKIGSNSIDLITK
YEPIFLGSGIYFLRPFNTDERDKLMVTDNAMSNWDEITETYYQKFGNAINKMLSLRLV
SLPNGHILQPGDSCVWLAEVVDMKDRFQTTLSLNILNSQRAEIFFNKTFTFNEDNGNF
LSYKIGDHGESTELGQITHSNKADINTAEIRSDEYLINTDNELFLRISKEIAEVKELL
NEIVSPHEMEVIFENMRNQPNNDFELALMNKLKSSLNDDNKVEQINNARMDDDESTSH
TTRDIGEAGSQTTGNTESEVTNVAAGVFIEHDEL"
rep_origin 567496..567742
/note="ARS419;
Autonomously Replicating Sequence"
/db_xref="SGD:S000118436"
gene complement(567723..568703)
/gene="TGL2"
/locus_tag="YDR058C"
/db_xref="GeneID:851628"
mRNA complement(567723..568703)
/gene="TGL2"
/locus_tag="YDR058C"
/product="Tgl2p"
/transcript_id="NM_001180366.1"
/db_xref="GI:296143412"
/db_xref="GeneID:851628"
CDS complement(567723..568703)
/gene="TGL2"
/locus_tag="YDR058C"
/EC_number="3.1.1.3"
/note="Triacylglycerol lipase that is localized to the
mitochondria; has lipolytic activity towards
triacylglycerols and diacylglycerols when expressed in E.
coli"
/codon_start=1
/product="Tgl2p"
/protein_id="NP_010343.1"
/db_xref="GI:6320263"
/db_xref="SGD:S000002465"
/db_xref="GeneID:851628"
/translation="MKNDNKANDIIIDSVKVPDSYKPPKNPIVFCHGLSGFDKLILIP
SVFHLTNLISNSIVHNMAENFMQDDEDKSDNKYTNLLEIEYWIGVKKFLQSKGCTVIT
TKVPGFGSIEERAMALDAQLQKEVKKIESKDKRHSLNLIAHSMGGLDCRYLICNIKNR
NYDILSLTTISTPHRGSEMADYVVDLFENLNALRVSQKILPICFYQLTTAYMKYFNLV
TPNSPKVSYFSYGCSFVPKWYNVFCTPWKIVYERSKGCPNDGLVTINSSKWGEYRGTL
KDMDHLDVINWKNKLQDDWSKFFRTTTVGEKVDILNFYLKITDDLARKGF"
gene 568882..568953
/locus_tag="tR(UCU)D"
/db_xref="GeneID:851629"
tRNA 568882..568953
/locus_tag="tR(UCU)D"
/product="tRNA-Arg"
/note="Arginine tRNA (tRNA-Arg), predicted by tRNAscan-SE
analysis; one of 11 nuclear tRNA genes containing the
tDNA-anticodon UCU (converted to mcm5-UCU in the mature
tRNA), decodes AGA codons into arginine, one of 19 nuclear
tRNAs for arginine"
/db_xref="SGD:S000006709"
/db_xref="GeneID:851629"
gene 568964..569035
/locus_tag="tD(GUC)D"
/db_xref="GeneID:851630"
tRNA 568964..569035
/locus_tag="tD(GUC)D"
/product="tRNA-Asp"
/note="Aspartate tRNA (tRNA-Asp), predicted by tRNAscan-SE
analysis"
/db_xref="SGD:S000006531"
/db_xref="GeneID:851630"
gene complement(569234..569770)
/gene="UBC5"
/locus_tag="YDR059C"
/db_xref="GeneID:851631"
mRNA complement(join(569234..569633,569724..569770))
/gene="UBC5"
/locus_tag="YDR059C"
/product="E2 ubiquitin-conjugating protein UBC5"
/transcript_id="NM_001180367.1"
/db_xref="GI:296143413"
/db_xref="GeneID:851631"
CDS complement(join(569234..569633,569724..569770))
/gene="UBC5"
/locus_tag="YDR059C"
/EC_number="6.3.2.19"
/note="Ubiquitin-conjugating enzyme; mediates selective
degradation of short-lived, abnormal, or excess proteins,
including histone H3; central component of the cellular
stress response; expression is heat inducible; protein
abundance increases in response to DNA replication stress"
/codon_start=1
/product="E2 ubiquitin-conjugating protein UBC5"
/protein_id="NP_010344.1"
/db_xref="GI:6320264"
/db_xref="SGD:S000002466"
/db_xref="GeneID:851631"
/translation="MSSSKRIAKELSDLGRDPPASCSAGPVGDDLYHWQASIMGPSDS
PYAGGVFFLSIHFPTDYPFKPPKVNFTTKIYHPNINSSGNICLDILKDQWSPALTLSK
VLLSICSLLTDANPDDPLVPEIAQIYKTDKAKYEATAKEWTKKYAV"
gene 570649..573726
/gene="MAK21"
/locus_tag="YDR060W"
/gene_synonym="NOC1"
/db_xref="GeneID:851632"
mRNA 570649..573726
/gene="MAK21"
/locus_tag="YDR060W"
/gene_synonym="NOC1"
/product="Mak21p"
/transcript_id="NM_001180368.3"
/db_xref="GI:398365318"
/db_xref="GeneID:851632"
CDS 570649..573726
/gene="MAK21"
/locus_tag="YDR060W"
/gene_synonym="NOC1"
/note="Constituent of 66S pre-ribosomal particles,
required for large (60S) ribosomal subunit biogenesis;
involved in nuclear export of pre-ribosomes; required for
maintenance of dsRNA virus; homolog of human CAATT-binding
protein"
/codon_start=1
/product="Mak21p"
/protein_id="NP_010345.3"
/db_xref="GI:398365319"
/db_xref="SGD:S000002467"
/db_xref="GeneID:851632"
/translation="MSENNGNPLDLSSLRNKISSKLRDNNSKKAKKTHKGKDVKASSN
SKKVNEDIRREALALGASEEDLKLIQGLSDDDDAKSEQEFDAVADEDADDKGFKNDLQ
NFMKNVGFDQHKLEDVDDDDIEEESTSSKESKIPAQEKEHAQSNIASSTIEKTSQESI
DNGSEQEENTVEEANLSSDQEPESESAEKEKKEEKDGGLITQTTIISSDKLIIPYDKP
WYEIPLDPQVGQNDDVEELSKEQIEKLFERGKQTLEADNQTYYEEFTKDSSQAKFMSQ
ILSDGTLNDKISAVTLLIQDSPLHNTKSLETLVSYCGKKSRNSALQSLNALKDLFLNG
LLPNRKLRYFKNQPGLSMMLNKKTLAIFYFEDYLKKLFFRVLEVLEVLSHDPIIHVRL
QILNHVFDLLTNQPEQEFNLLRLGVNKIGDIDSKVSSKASYLLLKLEQAHPNMKSIVI
DAIVDIALRPNADYHTTYYSVITLNQTILKRSEDSVANKLVKTYFTLFEKFLINTDKD
NTNGVVKSNSKSYEEKRKKNFKKGKHGGKSVKIEKTENEVLDEKNSKLFSALLTGINR
AFPFAQIPASVYEVHMETLFKITHSSNFNTSIQALVLINQVTVKAKLNSDRYYRTLYE
SLFDPRLVNSSKQGIYLNLLYKSLKQDALNVERVEAFVKRILQVCSHWLNVGTITGFF
FLLIQLAKTVPQIKNLLTNTPVDYEYESDAEEEQGDKDIKRKEYDGRKRDPKFANAEK
SSLWEINNFINHFHPTVKTYANAYVTGETEQIAKPDLGLFTLSHFLDRFVYRSAKQTN
TARGTSIMQPLFSGSRVNDSVLVKASDIMHDQGPVNTEDWLTKKVEDIKPEDKFFYQY
FTTKKTADGKGKKSNKASNFDSDDEMDENEIWSALVKSRPDVEDDSDDSELDFAEDDF
SDSTSDDEPKLDAIDDEDAKSEGSQESDQEEGLDEDIFYSFDGEQDNSDKKRSFAESS
EEDESSEEEKEEEENKEVSAKRAKKKQRKNMLKSLPVFASADDYAQYLDQDSD"
gene 574164..575783
/locus_tag="YDR061W"
/db_xref="GeneID:851633"
mRNA 574164..575783
/locus_tag="YDR061W"
/product="hypothetical protein"
/transcript_id="NM_001180369.3"
/db_xref="GI:398365332"
/db_xref="GeneID:851633"
CDS 574164..575783
/locus_tag="YDR061W"
/note="Protein with similarity to ATP-binding cassette
(ABC) transporter family members; lacks predicted
membrane-spanning regions; transcriptionally activated by
Yrm1p along with genes involved in multidrug resistance"
/codon_start=1
/product="hypothetical protein"
/protein_id="NP_010346.3"
/db_xref="GI:398365333"
/db_xref="SGD:S000002468"
/db_xref="GeneID:851633"
/translation="MSTNKFVVRITNALFKSSLASNSPPVYPKRIRHFEILPNEKWVI
WGPGKGKFLDVLNNKYICEPPLSLRFGFLKESSNILPRIEQVAFKGVMPTAHLSARYE
YFKDDYDQTCKQFIFDKASGSNAVSYKVETNNRQINMELYNALVENLNLSSLQDRWVM
GLSNGQMRRARLARSILKEPDLLLIDDPFLGLDPAAIATISQFLAKYDSIEVSGGCPI
VIGLRYQDTIPAWCTHICCVDEKNGILFEGPIEKLQSKMDETRSRALKELEQLKKASN
SKEDISINDLICIHPMYGKKEHEIIKMPHLIELDGLSVSYKGEAVLENLHWKVQPGSK
WHIRGDNGSGKSTLLSLLTAEHPQSWNSRVIDNGVPRRTGKTNYFDLNSKIGMSSPEL
HAIFLKNAGGRLNIRESVATGYHEASSNNYLPIWKRLDKNSQEIVNMYLKYFGLDKDA
DSVLFEQLSVSDQKLVLFVRSLIKMPQILILDEAFSGMEVEPMMRCHEFLEEWPGTVL
VVAHVAEETPKCAHYLRLISPGEYEIGDMEN"
gene 576474..578159
/gene="LCB2"
/locus_tag="YDR062W"
/gene_synonym="SCS1; TSC1"
/db_xref="GeneID:851634"
mRNA 576474..578159
/gene="LCB2"
/locus_tag="YDR062W"
/gene_synonym="SCS1; TSC1"
/product="serine C-palmitoyltransferase LCB2"
/transcript_id="NM_001180370.1"
/db_xref="GI:296143416"
/db_xref="GeneID:851634"
CDS 576474..578159
/gene="LCB2"
/locus_tag="YDR062W"
/gene_synonym="SCS1; TSC1"
/EC_number="2.3.1.50"
/note="Component of serine palmitoyltransferase,
responsible along with Lcb1p for the first committed step
in sphingolipid synthesis, which is the condensation of
serine with palmitoyl-CoA to form 3-ketosphinganine"
/codon_start=1
/product="serine C-palmitoyltransferase LCB2"
/protein_id="NP_010347.1"
/db_xref="GI:6320267"
/db_xref="SGD:S000002469"
/db_xref="GeneID:851634"
/translation="MSTPANYTRVPLCEPEELPDDIQKENEYGTLDSPGHLYQVKSRH
GKPLPEPVVDTPPYYISLLTYLNYLILIILGHVHDFLGMTFQKNKHLDLLEHDGLAPW
FSNFESFYVRRIKMRIDDCFSRPTTGVPGRFIRCIDRISHNINEYFTYSGAVYPCMNL
SSYNYLGFAQSKGQCTDAALESVDKYSIQSGGPRAQIGTTDLHIKAEKLVARFIGKED
ALVFSMGYGTNANLFNAFLDKKCLVISDELNHTSIRTGVRLSGAAVRTFKHGDMVGLE
KLIREQIVLGQPKTNRPWKKILICAEGLFSMEGTLCNLPKLVELKKKYKCYLFIDEAH
SIGAMGPTGRGVCEIFGVDPKDVDILMGTFTKSFGAAGGYIAADQWIIDRLRLDLTTV
SYSESMPAPVLAQTISSLQTISGEICPGQGTERLQRIAFNSRYLRLALQRLGFIVYGV
ADSPVIPLLLYCPSKMPAFSRMMLQRRIAVVVVAYPATPLIESRVRFCMSASLTKEDI
DYLLRHVSEVGDKLNLKSNSGKSSYDGKRQRWDIEEVIRRTPEDCKDDKYFVN"
gene 578663..579112
/gene="AIM7"
/locus_tag="YDR063W"
/gene_synonym="GMF1"
/db_xref="GeneID:851635"
mRNA 578663..579112
/gene="AIM7"
/locus_tag="YDR063W"
/gene_synonym="GMF1"
/product="Aim7p"
/transcript_id="NM_001180371.1"
/db_xref="GI:296143417"
/db_xref="GeneID:851635"
CDS 578663..579112
/gene="AIM7"
/locus_tag="YDR063W"
/gene_synonym="GMF1"
/note="Protein that interacts with Arp2/3 complex to
stimulate actin filament debranching and inhibit actin
nucleation; has similarity to Cof1p and also to human glia
maturation factor (GMF); null mutant displays elevated
mitochondrial genome loss"
/codon_start=1
/product="Aim7p"
/protein_id="NP_010348.1"
/db_xref="GI:6320268"
/db_xref="SGD:S000002470"
/db_xref="GeneID:851635"
/translation="MSNLYKIGTETRNKIKKFRTSTARTDSIKALSIKIEPKPSYEII
VDEDEQEELDEIEDLSELAEILPDNSPRFVLTAYPTTTKDGFKQTPLVLVYWKPMTVV
SQEWKMLYAGALEMIREECGTFKLIEVSSGLEDDSDVEELREQLENC"
gene 579458..580452
/gene="RPS13"
/locus_tag="YDR064W"
/gene_synonym="RPS13B; RPS13C"
/db_xref="GeneID:851636"
mRNA join(579458..579478,580018..580452)
/gene="RPS13"
/locus_tag="YDR064W"
/gene_synonym="RPS13B; RPS13C"
/product="ribosomal 40S subunit protein S13"
/transcript_id="NM_001180372.3"
/db_xref="GI:398365350"
/db_xref="GeneID:851636"
CDS join(579458..579478,580018..580452)
/gene="RPS13"
/locus_tag="YDR064W"
/gene_synonym="RPS13B; RPS13C"
/note="Protein component of the small (40S) ribosomal
subunit; homologous to mammalian ribosomal protein S13 and
bacterial S15"
/codon_start=1
/product="ribosomal 40S subunit protein S13"
/protein_id="NP_010349.3"
/db_xref="GI:398365351"
/db_xref="SGD:S000002471"
/db_xref="GeneID:851636"
/translation="MGRMHSAGKGISSSAIPYSRNAPAWFKLSSESVIEQIVKYARKG
LTPSQIGVLLRDAHGVTQARVITGNKIMRILKSNGLAPEIPEDLYYLIKKAVSVRKHL
ERNRKDKDAKFRLILIESRIHRLARYYRTVAVLPPNWKYESATASALVN"
gene 580687..581784
/gene="RRG1"
/locus_tag="YDR065W"
/db_xref="GeneID:851637"
mRNA 580687..581784
/gene="RRG1"
/locus_tag="YDR065W"
/product="Rrg1p"
/transcript_id="NM_001180373.3"
/db_xref="GI:398365356"
/db_xref="GeneID:851637"
CDS 580687..581784
/gene="RRG1"
/locus_tag="YDR065W"
/note="hypothetical protein, required for vacuolar
acidification and mitochondrial genome maintenance; the
authentic, non-tagged protein is detected in highly
purified mitochondria in high-throughput studies"
/codon_start=1
/product="Rrg1p"
/protein_id="NP_010350.3"
/db_xref="GI:398365357"
/db_xref="SGD:S000002472"
/db_xref="GeneID:851637"
/translation="MAQNFGKIPSHKSYVLSLYRTVLRNIPKCCHSYAFQYEIKKTLS
IQLFKHKHDKSSWSVYTLLNEFSLLNNCLLEGKLQEIKNLMKPLKKMKKQLKTTKILN
SLTSLGDVKTNDPEEVRRFHVLSAYIKRKQDLGLLPAYIPKTYQHKLLLPLALNEHAC
LKLFHIQQKLKNGPPSAGLSYTKEGRNQIWFVRSPINKGRQQSKKLGILIRKERKDSQ
KNIDNLNFCEINAAWALHEAIWEEYLESKKIIKVNLPKYLEYAANIPKSTKCNPSSQY
QKVKEWVDPVREIMFELHSKSFQRVEYFNKYKEKLLKNGGQLAYFDKKSKEMYAKRLT
LFRKMSKETLPYVTLFIEGRDLPSVLAKYGF"
gene complement(581908..582498)
/gene="RTR2"
/locus_tag="YDR066C"
/db_xref="GeneID:851638"
mRNA complement(581908..582498)
/gene="RTR2"
/locus_tag="YDR066C"
/product="Rtr2p"
/transcript_id="NM_001180374.1"
/db_xref="GI:296143420"
/db_xref="GeneID:851638"
CDS complement(581908..582498)
/gene="RTR2"
/locus_tag="YDR066C"
/note="hypothetical protein with high similarity to Rtr1p;
exhibits genetic interactions with Rtr1p; green
fluorescent protein (GFP)-fusion protein localizes to the
cytoplasm; YDR066C is not an essential gene; relocalizes
from nucleus to cytoplasmic foci upon DNA replication
stress"
/codon_start=1
/product="Rtr2p"
/protein_id="NP_010351.1"
/db_xref="GI:6320271"
/db_xref="SGD:S000002473"
/db_xref="GeneID:851638"
/translation="MQIITTTFIQKVILGSHQLHEQLSIVEARMIESAIVSMLTESFC
ENEQTLKYLARLLSPMSYMDVINARRGKKICGYPLCYKSAAENSSDGFFIHSMYCNNY
HSKCSLYLMRQLSQTPLHERRGVHLTSYINLEFDDMYSVSLLEELVGSEVPIDTVKSL
ITSFKDLEFDDTYKNEPLPLDVYFGQLTTDEETCIE"
gene complement(582791..583465)
/gene="OCA6"
/locus_tag="YDR067C"
/db_xref="GeneID:851639"
mRNA complement(582791..583465)
/gene="OCA6"
/locus_tag="YDR067C"
/product="Oca6p"
/transcript_id="NM_001180375.1"
/db_xref="GI:296143421"
/db_xref="GeneID:851639"
CDS complement(582791..583465)
/gene="OCA6"
/locus_tag="YDR067C"
/EC_number="3.1.3.48"
/note="Cytoplasmic protein required for replication of
Brome mosaic virus in S. cerevisiae, which is a model
system for studying positive-strand RNA virus replication;
null mutation confers sensitivity to tunicamycin and DTT"
/codon_start=1
/product="Oca6p"
/protein_id="NP_010352.1"
/db_xref="GI:6320272"
/db_xref="SGD:S000002474"
/db_xref="GeneID:851639"
/translation="MTLVTPLQFSTVQPNLYRGSYPREINLPFLRTLRLKYILSLTPE
PLSTDPLMVKFCEENNIKTIHIKCQSERKADKTKPKIKRKKKTVPIEYDVVVRCVKFL
IDKGHYPCYMHCTNGELIISLVVACMRKFSYWSTVSILNEFLVYNSSINIHERNFIEN
FNSEIEVDDLDIKDKVPWITVRYIARTATESKDELRVDDANASEKVARVSSVSNSLPK
LKFHSM"
gene 583713..584645
/gene="DOS2"
/locus_tag="YDR068W"
/db_xref="GeneID:851640"
mRNA 583713..584645
/gene="DOS2"
/locus_tag="YDR068W"
/product="Dos2p"
/transcript_id="NM_001180376.3"
/db_xref="GI:398365380"
/db_xref="GeneID:851640"
CDS 583713..584645
/gene="DOS2"
/locus_tag="YDR068W"
/note="hypothetical protein, green fluorescent protein
(GFP)-fusion protein localizes to the cytoplasm"
/codon_start=1
/product="Dos2p"
/protein_id="NP_010353.3"
/db_xref="GI:398365381"
/db_xref="SGD:S000002475"
/db_xref="GeneID:851640"
/translation="MEFFYEEQVACIEDDKISNSHTKETGSTENTENNELQSRDDKTN
EAFQKLEEEVNKRYEKTTSAFKKLVIEKDDGIEINLPISNETTETAQKYLKKLDENIH
SVESLAQSYWSKMKTKNFWSGFSSFDNAAENDSNDKDENSKENEIAVGGNRTEAELRT
LSKDKSVYLDNKMDLQLDPFDVDEKTEEICSILQGDKDISKLMNDIVPHKISYKDFWH
IYFLQRNKILDKESKRKEILSKKEKETEEKEVEWDDEEEEEDDDKVEAVADNKSKGET
KVAVSQEGLKDVSDHVGLANKDESKDDDDDDDWE"
gene complement(584939..587719)
/gene="DOA4"
/locus_tag="YDR069C"
/gene_synonym="DOS1; MUT4; NPI2; SSV7; UBP4"
/db_xref="GeneID:851641"
mRNA complement(584939..587719)
/gene="DOA4"
/locus_tag="YDR069C"
/gene_synonym="DOS1; MUT4; NPI2; SSV7; UBP4"
/product="Doa4p"
/transcript_id="NM_001180377.3"
/db_xref="GI:398365390"
/db_xref="GeneID:851641"
CDS complement(584939..587719)
/gene="DOA4"
/locus_tag="YDR069C"
/gene_synonym="DOS1; MUT4; NPI2; SSV7; UBP4"
/EC_number="3.1.2.15"
/note="Ubiquitin isopeptidase, required for recycling
ubiquitin from proteasome-bound ubiquitinated
intermediates, acts at the late endosome/prevacuolar
compartment to recover ubiquitin from ubiquitinated
membrane proteins en route to the vacuole"
/codon_start=1
/product="Doa4p"
/protein_id="NP_010354.3"
/db_xref="GI:398365391"
/db_xref="SGD:S000002476"
/db_xref="GeneID:851641"
/translation="MEQNIISTIRDECIRHRSKYLTIAQLTAIAEAKINEFIITGKAK
DQDLSSLLDKCIDILSIYKKNSKDIKNIISCKNKGAMISSNSVMIIQLNYVYYKVIHI
IVTTNIPHLSEFAKIKLHKSTSDEGNGNNNNNEFQLMNIYNTLLETLLKDENIAKIKS
FIKSSIKQTKLNHEQEECNLMRTGSYITSNQLNSLISSSANSASSQMEILLIDIRSRL
EFNKSHIDTKNIICLEPISFKMSYSDHDLEKKSLITSPNSEIKMFQSRNLFKFIILYT
DANEYNVKQQSVLLDILVNHSFEKPISDDFTKIFILESGFPGWLKSNYGRQVSSSFPS
NNNIKDDSVYINGNTSGLSLQHLPKMSPSIRHSMDDSMKEMLVAPTPLNHLQQQQQQQ
SDNDHVLKRSSSFKKLFSNYTSPNPKNSNSNLYSISSLSISSSPSPLPLHSPDPVKGN
SLPINYPETPHLWKNSETDFMTNQREQLNHNSFAHIAPINTKAITSPSRTATPKLQRF
PQTISMNLNMNSNGHSSATSTIQPSCLSLSNNDSLDHTDVTPTSSHNYDLDFAVGLEN
LGNSCYMNCIIQCILGTHELTQIFLDDSYAKHININSKLGSKGILAKYFARLVHMMYK
EQVDGSKKISISPIKFKLACGSVNSLFKTASQQDCQEFCQFLLDGLHEDLNQCGSNPP
LKELSQEAEARREKLSLRIASSIEWERFLTTDFSVIVDLFQGQYASRLKCKVCSHTST
TYQPFTVLSIPIPKKNSRNNITIEDCFREFTKCENLEVDEQWLCPHCEKRQPSTKQLT
ITRLPRNLIVHLKRFDNLLNKNNDFVIYPFLLDLTPFWANDFDGVFPPGVNDDELPIR
GQIPPFKYELYGVACHFGTLYGGHYTAYVKKGLKKGWLYFDDTKYKPVKNKADAINSN
AYVLFYHRVYGV"
gene complement(588098..588379)
/gene="FMP16"
/locus_tag="YDR070C"
/db_xref="GeneID:851642"
mRNA complement(588098..588379)
/gene="FMP16"
/locus_tag="YDR070C"
/product="Fmp16p"
/transcript_id="NM_001180378.1"
/db_xref="GI:296143424"
/db_xref="GeneID:851642"
CDS complement(588098..588379)
/gene="FMP16"
/locus_tag="YDR070C"
/note="hypothetical protein; proposed to be involved in
responding to conditions of stress; the authentic,
non-tagged protein is detected in highly purified
mitochondria in high-throughput studies; protein abundance
increases in response to DNA replication stress"
/codon_start=1
/product="Fmp16p"
/protein_id="NP_010355.1"
/db_xref="GI:6320275"
/db_xref="SGD:S000002477"
/db_xref="GeneID:851642"
/translation="MLRTTFLRTPRQLMRKSPRASFSIVTRAAFPHLKNNQDEAEKKE
QGLFDSNKKRLDTLEHGKNPDYKQPGMEDLKKKGDDARIEQNRPDDGVY"
gene complement(588827..589402)
/gene="PAA1"
/locus_tag="YDR071C"
/db_xref="GeneID:851643"
mRNA complement(588827..589402)
/gene="PAA1"
/locus_tag="YDR071C"
/product="Paa1p"
/transcript_id="NM_001180379.1"
/db_xref="GI:296143425"
/db_xref="GeneID:851643"
CDS complement(588827..589402)
/gene="PAA1"
/locus_tag="YDR071C"
/EC_number="2.3.1.-"
/note="Polyamine acetyltransferase; acetylates polyamines
(e.g. putrescine, spermidine, spermine) and also
aralkylamines (e.g. tryptamine, phenylethylamine); may be
involved in transcription and/or DNA replication"
/codon_start=1
/product="Paa1p"
/protein_id="NP_010356.1"
/db_xref="GI:6320276"
/db_xref="SGD:S000002478"
/db_xref="GeneID:851643"
/translation="MASSSSTLPLHMYIRPLIIEDLKQILNLESQGFPPNERASEEII
SFRLINCPELCSGLFIREIEGKEVKKETLIGHIMGTKIPHEYITIESMGKLQVESSNH
IGIHSVVIKPEYQKKNLATLLLTDYIQKLSNQEIGNKIVLIAHEPLIPFYERVGFKII
AENTNVAKDKNFAEQKWIDMERELIKEEYDN"
gene complement(589761..591344)
/gene="IPT1"
/locus_tag="YDR072C"
/gene_synonym="KTI6; SYR4"
/db_xref="GeneID:851644"
mRNA complement(589761..591344)
/gene="IPT1"
/locus_tag="YDR072C"
/gene_synonym="KTI6; SYR4"
/product="inositolphosphotransferase"
/transcript_id="NM_001180380.3"
/db_xref="GI:398365414"
/db_xref="GeneID:851644"
CDS complement(589761..591344)
/gene="IPT1"
/locus_tag="YDR072C"
/gene_synonym="KTI6; SYR4"
/EC_number="2.-.-.-"
/note="Inositolphosphotransferase, involved in synthesis
of mannose-(inositol-P)2-ceramide (M(IP)2C), the most
abundant sphingolipid; can mutate to resistance to the
antifungals syringomycin E and DmAMP1 and to K. lactis
zymocin"
/codon_start=1
/product="inositolphosphotransferase"
/protein_id="NP_010357.3"
/db_xref="GI:398365415"
/db_xref="SGD:S000002479"
/db_xref="GeneID:851644"
/translation="MNVIFSLASFVKNMYNASLNQRNLISLPFNFMLNFAPVFIWLSI
FKRAGLIPIRLRPDIHSKFAFFADQFLFGDYWHELTVQLPDNTSKLFFWSFISSSAFL
LVFLICIPFAIWYYIYYIKHVNYNLLEWFANIFHYPCKRKQRPIQKRFRTIFIPFALP
LFTFVILNIDHFFAYQSDANFTKTKDLLAWFSYVILHLTAPILTAVYLYVFQPPGTLK
CFSFALGLQNIAGVLTHLLVPMASPWFTHLYGIDDTEHVNYTQEGFAAGLIRVDSHLG
THLNTKGFHMSPIVFGAVPSLHSAIAFQCFLFLVSRSTSLKHRFSNAGGFTMHNNDSS
TFKLSEEDSEDEGDNSIPPTIGPNDLEMEPLGTVEPVDISNERSSSPSSSFTVSSNER
STGGGDGSIINSNGNKKPLQFVHLYDEDTNFTNKWIFKIVNDGFIPKFWAILYIILQW
WATMYLDHHYRFDLFVGVLYAMTSFIIINWFVLQPKVLKKWIHIRLGDKVDTRNEART
FGMRVFCGTKMEWFFDPLA"
gene 592439..592948
/gene="SNF11"
/locus_tag="YDR073W"
/db_xref="GeneID:851645"
mRNA 592439..592948
/gene="SNF11"
/locus_tag="YDR073W"
/product="Snf11p"
/transcript_id="NM_001180381.3"
/db_xref="GI:398365424"
/db_xref="GeneID:851645"
CDS 592439..592948
/gene="SNF11"
/locus_tag="YDR073W"
/note="Subunit of the SWI/SNF chromatin remodeling
complex; involved in transcriptional regulation; interacts
with a highly conserved 40-residue sequence of Snf2p;
relocates to the cytosol under hypoxic conditions"
/codon_start=1
/product="Snf11p"
/protein_id="NP_010358.3"
/db_xref="GI:398365425"
/db_xref="SGD:S000002480"
/db_xref="GeneID:851645"
/translation="MSSEIAYSNTNTNTENENRNTGAGVDVNTNANANANATANATAN
ATANATAELNLPTVDEQRQYKVQLLLHINSILLARVIQMNNSLQNNLQNNINNSNNNN
IIRIQQLISQFLKRVHANLQCISQINQGVPSAKPLILTPPQLANQQQPPQDILSKLYL
LLARVFEIW"
gene 593893..596583
/gene="TPS2"
/locus_tag="YDR074W"
/gene_synonym="HOG2; PFK3"
/db_xref="GeneID:851646"
mRNA 593893..596583
/gene="TPS2"
/locus_tag="YDR074W"
/gene_synonym="HOG2; PFK3"
/product="trehalose-phosphatase TPS2"
/transcript_id="NM_001180382.1"
/db_xref="GI:296143428"
/db_xref="GeneID:851646"
CDS 593893..596583
/gene="TPS2"
/locus_tag="YDR074W"
/gene_synonym="HOG2; PFK3"
/EC_number="3.1.3.12"
/note="Phosphatase subunit of the trehalose-6-P
synthase/phosphatase complex; involved in synthesis of the
storage carbohydrate trehalose; expression is induced by
stress conditions and repressed by the Ras-cAMP pathway;
protein abundance increases in response to DNA replication
stress"
/codon_start=1
/product="trehalose-phosphatase TPS2"
/protein_id="NP_010359.1"
/db_xref="GI:6320279"
/db_xref="SGD:S000002481"
/db_xref="GeneID:851646"
/translation="MTTTAQDNSPKKRQRIINCVTQLPYKIQLGESNDDWKISATTGN
SALFSSLEYLQFDSTEYEQHVVGWTGEITRTERNLFTREAKEKPQDLDDDPLYLTKEQ
INGLTTTLQDHMKSDKEAKTDTTQTAPVTNNVHPVWLLRKNQSRWRNYAEKVIWPTFH
YILNPSNEGEQEKNWWYDYVKFNEAYAQKIGEVYRKGDIIWIHDYYLLLLPQLLRMKF
NDESIIIGYFHHAPWPSNEYFRCLPRRKQILDGLVGANRICFQNESFSRHFVSSCKRL
LDATAKKSKNSSNSDQYQVSVYGGDVLVDSLPIGVNTTQILKDAFTKDIDSKVLSIKQ
AYQNKKIIIGRDRLDSVRGVVQKLRAFETFLAMYPEWRDQVVLIQVSSPTANRNSPQT
IRLEQQVNELVNSINSEYGNLNFSPVQHYYMRIPKDVYLSLLRVADLCLITSVRDGMN
TTALEYVTVKSHMSNFLCYGNPLILSEFSGSSNVLKDAIVVNPWDSVAVAKSINMALK
LDKEEKSNLESKLWKEVPTIQDWTNKFLSSLKEQASSNDDMERKMTPALNRPVLLENY
KQAKRRLFLFDYDGTLTPIVKDPAAAIPSARLYTILQKLCADPHNQIWIISGRDQKFL
NKWLGGKLPQLGLSAEHGCFMKDVSCQDWVNLTEKVDMSWQVRVNEVMEEFTTRTPGS
FIERKKVALTWHYRRTVPELGEFHAKELKEKLLSFTDDFDLEVMDGKANIEVRPRFVN
KGEIVKRLVWHQHGKPQDMLKGISEKLPKDEMPDFVLCLGDDFTDEDMFRQLNTIETC
WKEKYPDQKNQWGNYGFYPVTVGSASKKTVAKAHLTDPQQVLETLGLLVGDVSLFQSA
GTVDLDSRGHVKNSESSLKSKLASKAYVMKRSASYTGAKV"
gene 597156..598082
/gene="PPH3"
/locus_tag="YDR075W"
/db_xref="GeneID:851647"
mRNA 597156..598082
/gene="PPH3"
/locus_tag="YDR075W"
/product="Pph3p"
/transcript_id="NM_001180383.1"
/db_xref="GI:296143429"
/db_xref="GeneID:851647"
CDS 597156..598082
/gene="PPH3"
/locus_tag="YDR075W"
/EC_number="3.1.3.16"
/note="Catalytic subunit of protein phosphatase PP4
complex; active complex is composed of Pph3p and Psy2p,
with Psy4p apparently providing additional substrate
specificity in some cases; regulates recovery from the DNA
damage checkpoint and also the gene conversion- and
single-strand annealing-mediated pathways of meiotic
double-strand break repair; involved in activation of
Gln3p to alleviate nitrogen catabolite repression; Pph3p
and Psy2p localize to foci on meiotic chromosomes"
/codon_start=1
/product="Pph3p"
/protein_id="NP_010360.1"
/db_xref="GI:6320280"
/db_xref="SGD:S000002482"
/db_xref="GeneID:851647"
/translation="MMDLDKIIASLRDGKHIPEETVFRLCLNSQELLMNEGNVTQVDT
PVTICGDIHGQLHDLLTLFEKSGGVEKTRYIFLGDFVDRGFYSLESFLLLLCYKLRYP
DRITLIRGNHETRQITKVYGFYDEVVRKYGNSNVWRYCCEVFDYLSLGAIINNSIFCV
HGGLSPDMTTVDEIRTIDRKQEVPHEGAMCDLLWSDPEDVDTWSLSPRGAGFLFGKRE
VDQFLEKNNVELIARAHQLVMEGYKEMFDGGLVTVWSAPNYCYRCGNVAAVLKIDDDL
NREYTIFEAVQAQNEVGNAIIPTKKSQMDYFL"
gene 598468..599688
/gene="RAD55"
/locus_tag="YDR076W"
/db_xref="GeneID:851648"
mRNA 598468..599688
/gene="RAD55"
/locus_tag="YDR076W"
/product="Rad55p"
/transcript_id="NM_001180384.3"
/db_xref="GI:398365442"
/db_xref="GeneID:851648"
CDS 598468..599688
/gene="RAD55"
/locus_tag="YDR076W"
/note="Protein that stimulates strand exchange by
stabilizing the binding of Rad51p to single-stranded DNA;
involved in the recombinational repair of double-strand
breaks in DNA during vegetative growth and meiosis; forms
heterodimer with Rad57p"
/codon_start=1
/product="Rad55p"
/protein_id="NP_010361.3"
/db_xref="GI:398365443"
/db_xref="SGD:S000002483"
/db_xref="GeneID:851648"
/translation="MSLGIPLSQLIVESPKPLSSGITGLDEILNLGFQARSIYEIFGP
PGIGKTNFGIQLVCNSLEGIQQSEINDDKILWIETFQEMPINILRERFQKFKIVEENV
KRVRITKFGQLLYFFQNLFKLSQSVRYKLVIIDGFSQLVCDHLCTLSKRGGGMIDKTI
HELKCRHLILIFTVMTKYTHSTGSTIIVLNDCMNTAFQSNEFESLEEYYEILDDGSNF
FVNSNNERRKNNVHILKSALVANIAMGSKDSTWEVFLRDRIGLFRDWNEQVDETVFVK
SKRVKASSSQSNEGCTTIKEMRINKRNFENLRIAIVFNLHGEDRKREGRNLKRSRSSD
DRNYIVKFDFDKATGQLRDIIDLKPDTANIASFPTLSTSSSSCSQVFNNIDSNDNPLP
NAEGKEEIIYDSEG"
gene 600793..601809
/gene="SED1"
/locus_tag="YDR077W"
/db_xref="GeneID:851649"
mRNA 600793..601809
/gene="SED1"
/locus_tag="YDR077W"
/product="Sed1p"
/transcript_id="NM_001180385.3"
/db_xref="GI:398365448"
/db_xref="GeneID:851649"
CDS 600793..601809
/gene="SED1"
/locus_tag="YDR077W"
/note="Major stress-induced structural GPI-cell wall
glycoprotein in stationary-phase cells, associates with
translating ribosomes, possible role in mitochondrial
genome maintenance; ORF contains two distinct variable
minisatellites"
/codon_start=1
/product="Sed1p"
/protein_id="NP_010362.3"
/db_xref="GI:398365449"
/db_xref="SGD:S000002484"
/db_xref="GeneID:851649"
/translation="MKLSTVLLSAGLASTTLAQFSNSTSASSTDVTSSSSISTSSGSV
TITSSEAPESDNGTSTAAPTETSTEAPTTAIPTNGTSTEAPTTAIPTNGTSTEAPTDT
TTEAPTTALPTNGTSTEAPTDTTTEAPTTGLPTNGTTSAFPPTTSLPPSNTTTTPPYN
PSTDYTTDYTVVTEYTTYCPEPTTFTTNGKTYTVTEPTTLTITDCPCTIEKPTTTSTT
EYTVVTEYTTYCPEPTTFTTNGKTYTVTEPTTLTITDCPCTIEKSEAPESSVPVTESK
GTTTKETGVTTKQTTANPSLTVSTVVPVSSSASSHSVVINSNGANVVVPGALGLAGVA
MLFL"
gene complement(602198..602869)
/gene="SHU2"
/locus_tag="YDR078C"
/db_xref="GeneID:851650"
mRNA complement(602198..602869)
/gene="SHU2"
/locus_tag="YDR078C"
/product="Shu2p"
/transcript_id="NM_001180386.1"
/db_xref="GI:296143432"
/db_xref="GeneID:851650"
CDS complement(602198..602869)
/gene="SHU2"
/locus_tag="YDR078C"
/note="Component of the Shu complex, which promotes
error-free DNA repair; Shu complex mediates inhibition of
Srs2p function"
/codon_start=1
/product="Shu2p"
/protein_id="NP_010363.1"
/db_xref="GI:6320283"
/db_xref="SGD:S000002485"
/db_xref="GeneID:851650"
/translation="MSKDVIEYSKLFAKLVNTNDDTKLDDTIASFLYYMFPRELFIRA
ISLLESSDMFIYILDRVHNKEGNEHTSLIDVLVDEFYKGSSNSLLEYRLIVKDTNDGA
PPILVDIAHWFCSCEEFCKYFHEALEKTDEKEELHDVLINEVDDHLQFSDDRFAQLDP
HSLSKQWYFKFDKVCCSHLLAFSILLRSSINVLKFFTVNSNKVFVIAIDNIDEWLNLH
INIVE"
gene 603064..603399
/gene="PET100"
/locus_tag="YDR079W"
/db_xref="GeneID:851651"
mRNA 603064..603399
/gene="PET100"
/locus_tag="YDR079W"
/product="Pet100p"
/transcript_id="NM_001180387.1"
/db_xref="GI:296143433"
/db_xref="GeneID:851651"
CDS 603064..603399
/gene="PET100"
/locus_tag="YDR079W"
/note="Chaperone that specifically facilitates the
assembly of cytochrome c oxidase, integral to the
mitochondrial inner membrane; interacts with a subcomplex
of subunits VII, VIIa, and VIII (Cox7p, Cox9p, and Cox8p)
but not with the holoenzyme"
/codon_start=1
/product="Pet100p"
/protein_id="NP_010364.1"
/db_xref="GI:6320284"
/db_xref="SGD:S000002486"
/db_xref="GeneID:851651"
/translation="MGLFNNFKFKYTRAQLEIFRFSFCLLAPVAVMYYIGTDTDKKLN
VPGFWPDPATLNQIPKEPYEIKAELARMKKERLEKRLRLEKKIQEEFGLDLEEEKEKI
KRDLALKKG"
gene complement(603593..603811)
/gene="TFB5"
/locus_tag="YDR079C-A"
/db_xref="GeneID:851652"
mRNA complement(603593..603811)
/gene="TFB5"
/locus_tag="YDR079C-A"
/product="Tfb5p"
/transcript_id="NM_001184469.3"
/db_xref="GI:398365464"
/db_xref="GeneID:851652"
CDS complement(603593..603811)
/gene="TFB5"
/locus_tag="YDR079C-A"
/note="Component of the RNA polymerase II general
transcription and DNA repair factor TFIIH; involved in
transcription initiation and in nucleotide-excision
repair; homolog of Chlamydomonas reinhardtii REX1-S
protein involved in DNA repair"
/codon_start=1
/product="Tfb5p"
/protein_id="NP_076886.3"
/db_xref="GI:398365465"
/db_xref="SGD:S000007603"
/db_xref="GeneID:851652"
/translation="MARARKGALVQCDPSIKALILQIDAKMSDIVLEELDDTHLLVNP
SKVEFVKHELNRLLSKNIYNPMDEEENQ"
gene 604008..606986
/gene="VPS41"
/locus_tag="YDR080W"
/gene_synonym="CVT8; FET2; SVL2; VAM2; VPL20"
/db_xref="GeneID:851653"
mRNA 604008..606986
/gene="VPS41"
/locus_tag="YDR080W"
/gene_synonym="CVT8; FET2; SVL2; VAM2; VPL20"
/product="Vps41p"
/transcript_id="NM_001180388.3"
/db_xref="GI:398365474"
/db_xref="GeneID:851653"
CDS 604008..606986
/gene="VPS41"
/locus_tag="YDR080W"
/gene_synonym="CVT8; FET2; SVL2; VAM2; VPL20"
/note="Vacuolar membrane protein that is a subunit of the
homotypic vacuole fusion and vacuole protein sorting
(HOPS) complex; essential for membrane docking and fusion
at the Golgi-to-endosome and endosome-to-vacuole stages of
protein transport"
/codon_start=1
/product="Vps41p"
/protein_id="NP_010365.3"
/db_xref="GI:398365475"
/db_xref="SGD:S000002487"
/db_xref="GeneID:851653"
/translation="MTTDNHQNDSVLDQQSGERTIDESNSISDENNVDNKREDVNVTS
PTKSVSCISQAENGVASRTDESTITGSATDAETGDDDDDDDDDDDEDEDDEDEPPLLK
YTRISQLPKNFFQRDSISSCLFGDTFFAFGTHSGILHLTTCAFEPIKTIKCHRSSILC
INTDGKYFATGSIDGTVIIGSMDDPQNITQYDFKRPINSVALHSNFQASRMFVSGGMA
GDVVLSQRNWLGNRIDIVLNKKKKKKTRKDDLSSDMKGPIMGIYTMGDLILWMDDDGI
TFCDVPTRSQLLNIPFPSRIFNVQDVRPDLFRPHVHFLESDRVVIGWGSNIWLFKVSF
TKDSNSIKSGDSNSQSNNMSHFNPTTNIGSLLSSAASSFRGTPDKKVELECHFTVSML
ITGLASFKDDQLLCLGFDIDIEEEATIDEDMKEGKNFSKRPENLLAKGNAPELKIVDL
FNGDEIYNDEVIMKNYEKLSINDYHLGKHIDKTTPEYYLISSNDAIRVQELSLKDHFD
WFMERKQYYKAWKIGKYVIGSEERFSIGLKFLNSLVTKKDWGTLVDHLNIIFEETLNS
LDSNSYDVTQNVLKEWADIIEILITSGNIVEIAPLIPKKPALRKSVYDDVLHYFLAND
MINKFHEYITKWDLKLFSVEDFEEELETRIEAASEPTASSKEEGSNITYRTELVHLYL
KENKYTKAIPHLLKAKDLRALTIIKIQNLLPQYLDQIVDIILLPYKGEISHISKLSIF
EIQTIFNKPIDLLFENRHTISVARIYEIFEHDCPKSFKKILFCYLIKFLDTDDSFMIS
PYENQLIELYSEYDRQSLLPFLQKHNNYNVESAIEVCSSKLGLYNELIYLWGKIGETK
KALSLIIDELKNPQLAIDFVKNWGDSELWEFMINYSLDKPNFTKAILTCSDETSEIYL
KVIRGMSDDLQIDNLQDIIKHIVQENSLSLEVRDNILVIINDETKKFANEFLKIRSQG
KLFQVDESDIEINDDLNGVL"
gene complement(607304..610081)
/gene="PDC2"
/locus_tag="YDR081C"
/db_xref="GeneID:851654"
mRNA complement(607304..610081)
/gene="PDC2"
/locus_tag="YDR081C"
/product="Pdc2p"
/transcript_id="NM_001180389.1"
/db_xref="GI:296143436"
/db_xref="GeneID:851654"
CDS complement(607304..610081)
/gene="PDC2"
/locus_tag="YDR081C"
/note="Transcription factor for thiamine-regulated genes;
required for expression of the two isoforms of pyruvate
decarboxylase (PDC1 and PDC5) along with thiamine
biosynthetic genes; binds a DNA sequence in the PDC5
promoter; mutant fails to grow on 2% glucose and thus is
scored as inviable under standard conditions"
/codon_start=1
/product="Pdc2p"
/protein_id="NP_010366.1"
/db_xref="GI:6320286"
/db_xref="SGD:S000002488"
/db_xref="GeneID:851654"
/translation="MLSIQQRYNICLMAERHPKWTQLELAKWAYETFQLPKIPSQGTI
SRLLARKSTYMNCKEHEKDANRLRKPNNLLVRKILQEWISQSLWNGIPITSPIIQDTA
QAVWHRIPAEHREGNGSFSYKWISNFLSKMDVNISVLDEELPKTPKVWTFEERDVLKA
YFSKIPPKDLFTLDEAFLSYNLPLDYAQYEASSIQRRIEVATVMLCSNLDGSEKLKPV
VVGKYDSYKSFRNYFPNEPNDPVSQSMLGTKMAKKFDISYHSNRKAWLTSNLFHNWLV
RWDKRLVAVNRKIWIVLDDSCCHRIINLRLQNIKLVYTSSNSKFLPFNWGVWDEFKTR
YRIQQYQALIDLQNRISKNIQNKNKSERNECIPNGKKCLISFEQSQLTMSNAFKFIKK
AWDDIPVDAIKANWKSSGLLPPEMIHLNENVSMAFKKNEVLESVLNRLCDEYYCVKKW
EYEMLLDLNIENKNTNFLSTEELVESAIVEPCEPDFDTAPKGNEVHDDNFDVSVFANE
DDNNQNHLSMSQASHNPDYNSNHSNNAIENTNNRGSNNNNNNNGSSNNINDNDSSVKY
LQQNTVDNSTKTGNPGQPNISSMESQRNSSTTDLVVDGNYDVNFNGLLNDPYNTMKQP
GPLDYNVSTLIDKPNLFLSPDLDLSTVGVDMQLPSSEYFSEVFSSAIRNNEKAASDQN
KSTDELPSSTAMANSNSITTALLESRNQAQPFDVPHMNGLLSDTSKSGHSVNSSNAIS
QNSLNNFQHNSASVAEASSPSITPSPVAINSTGAPARSIISAPIDSNSSASSPSALEH
LEGAVSGMSPSSTTILSNLQTNINIAKSLSTIMKHAESNEISLTKETINELNFNYLTL
LKRIKKTRKQLNSESIKINSKNAQDHLETLLSGAAAAAATSANNLDLPTGGSNLPDSN
NLHLPGNTGFF"
gene 610441..611925
/gene="STN1"
/locus_tag="YDR082W"
/db_xref="GeneID:851655"
mRNA 610441..611925
/gene="STN1"
/locus_tag="YDR082W"
/product="Stn1p"
/transcript_id="NM_001180390.1"
/db_xref="GI:296143437"
/db_xref="GeneID:851655"
CDS 610441..611925
/gene="STN1"
/locus_tag="YDR082W"
/note="Telomere end-binding and capping protein, plays a
key role with Pol12p in linking telomerase action with
completion of lagging strand synthesis, and in a
regulatory step required for telomere capping"
/codon_start=1
/product="Stn1p"
/protein_id="NP_010367.1"
/db_xref="GI:6320287"
/db_xref="SGD:S000002489"
/db_xref="GeneID:851655"
/translation="MDKYGHIAHQEGDVCYYIPRLFKYNSYYSGTEDVRIFVGDLKYR
MRVSLQICEKYYDRRLSMLFWKNHPLQQIHLIGCIIGLQFKWIGKQEYIFFQLDDCTS
DSSLVGYTSDMRFLTCKVKKDSILSWGLNITDLIGLTLHVYGQASLNYQELQVEYLRL
CYSLTEEIDHWKITMNMREQLDTPWSLSDFVIGELFTQEQEWTPETSQIEVVNPDFVG
IGYKTPESKRNETTFIEQLQEERLKDELEIISPYNSTDTSNSVHSLSFRFVSSLKDFP
ETHFLNSGDQIDNGNDEQLKKLEYQSANLPVMIPNRTSAKSNLMLILLGLQMKEISNS
DLYKLKEVRSVVTSLASFLFQQQNVGVMKSFDSLEKEAFRDLVNRLVSQGLIGLKDKT
SETFDLLPLKNLFEYAEKRISVLMKLQCYTGTVQLSHVQEKLHLPYITTNGIVDVFKE
CLKRTKKQYPEVLKNWWIDLDPKNGMEDQNSGILLHLEYAAAYS"
gene 612073..613251
/gene="RRP8"
/locus_tag="YDR083W"
/db_xref="GeneID:851656"
mRNA 612073..613251
/gene="RRP8"
/locus_tag="YDR083W"
/product="Rrp8p"
/transcript_id="NM_001180391.3"
/db_xref="GI:398365486"
/db_xref="GeneID:851656"
CDS 612073..613251
/gene="RRP8"
/locus_tag="YDR083W"
/note="Nucleolar protein involved in rRNA processing,
pre-rRNA cleavage at site A2; also involved in telomere
maintenance; mutation is synthetically lethal with a gar1
mutation"
/codon_start=1
/product="Rrp8p"
/protein_id="NP_010368.5"
/db_xref="GI:398365487"
/db_xref="SGD:S000002490"
/db_xref="GeneID:851656"
/translation="MALFNVEGWSIKTKTVAFDNKTNKSSKDKKKNNRKNGKLTREQK
LKEETEAELKEQVEDIPSEGSVAKDIPKKNQEKSDQNETSKKRKHDEEAPLMQVKENI
EKPTKKQLTPLQQKMMAKLTGSRFRWINEQLYTISSDEALKLIKEQPQLFDEYHDGFR
SQVQAWPENPVDVFVDQIRYRCMKPVNAPGGLPGLKDSKEIVIADMGCGEAQLALEIN
NFFKNYNKKAKKYLKRRHKVHSFDLKKANERITVADIRNVPLPDESCTIVVFCLALMG
TNFLDFIKEAYRILAPRGELWIAEIKSRFSDGKGNEFVDALKLMGFFHKKTFDENKMF
TRFEFFKPPAEIIEERRQKLERRQKFIEVETEKEELEKKRRKIAEGKWLLKPCIYKRR
"
gene complement(613405..614004)
/gene="TVP23"
/locus_tag="YDR084C"
/db_xref="GeneID:851657"
mRNA complement(613405..614004)
/gene="TVP23"
/locus_tag="YDR084C"
/product="Tvp23p"
/transcript_id="NM_001180392.3"
/db_xref="GI:398365490"
/db_xref="GeneID:851657"
CDS complement(613405..614004)
/gene="TVP23"
/locus_tag="YDR084C"
/note="Integral membrane protein localized to late Golgi
vesicles along with the v-SNARE Tlg2p; green fluorescent
protein (GFP)-fusion protein localizes to the cytoplasm in
a punctate pattern"
/codon_start=1
/product="Tvp23p"
/protein_id="NP_010369.3"
/db_xref="GI:398365491"
/db_xref="SGD:S000002491"
/db_xref="GeneID:851657"
/translation="MDQARNFYNTILKSSHPLLLSFHLAGKAVPIVFYIIGSMFLNFT
PQFITVVLLLSFDFYLTKNITGRKLVQLRWWYDSTDVNKDSNFTFESYKQYAPGPPIN
AIDSKLFWWSMYVTPVIWGVFAVLCLLRLKIFYLILVIVAMCLTAWNTYGFRCCDRWE
PNSGQSDGQDTNNWFALPSVPGFENLSRLANIQSFFQRQ"
gene complement(614288..616150)
/gene="AFR1"
/locus_tag="YDR085C"
/db_xref="GeneID:851658"
mRNA complement(614288..616150)
/gene="AFR1"
/locus_tag="YDR085C"
/product="Afr1p"
/transcript_id="NM_001180393.1"
/db_xref="GI:296143440"
/db_xref="GeneID:851658"
CDS complement(614288..616150)
/gene="AFR1"
/locus_tag="YDR085C"
/note="Protein required for pheromone-induced projection
(shmoo) formation; regulates septin architecture during
mating; has an RVXF motif that mediates targeting of Glc7p
to mating projections; interacts with Cdc12p; AFR1 has a
paralog, YER158C, that arose from the whole genome
duplication"
/codon_start=1
/product="Afr1p"
/protein_id="NP_010370.1"
/db_xref="GI:6320290"
/db_xref="SGD:S000002492"
/db_xref="GeneID:851658"
/translation="MEGSYLSAQENQPIPERLIPRSNSTSNLFALSSTFSKLNVRNDA
DYNYSNPNKKRHIYSGEIDCRSVTAARKFPVRSCSMTAAQQRKRTALFTVRERNSYHE
GFNNDQDYVSQYQKPQYTFGVYKELTPYQLQRSKMKRSFQFPNGEIYKPKLDGKCTHS
LKKPELNSRDSSLFKFSEKKGRNLSKDFVGPHNGTSVIHIPPNDTGYGVNSLELNTSV
PSTIKSSVSSTSPISAVNTLTSLPESQTDDDDGYENKTVTISYCFENTVNEKHGSHIE
KLDLSTKEKTKPTTNSGLFDRKKKTILGTEKYRCIKSQSKLKLGSVLKKLWRTSGNSN
TKHGKKDTKRRRIPIDDMVTHSDGNSEAENDIELMDANLDGIEFDDDETLMDTDSIFD
DLLSKENDKYDLRRRQLEIRQKLHETSHNDDGKVSFRDTEKHNVNEGLIDKTIIEEFS
KLGEYIIDTRNQPPPRSSKRPSLDDNESARYFYNISTDLRQSLSGPISLPMHVGNDMV
NRLRNDWEYIRFEDRRNSLPDSSFDKVETPPKPIKKDVRFAKEVCLASTWSSNAYERA
NPEFIMNRHRLLWMMKVHPSMNSAMNEIKLELNSYKKNEMVVHENSKCFTHYLI"
gene complement(616928..617170)
/gene="SSS1"
/locus_tag="YDR086C"
/db_xref="GeneID:851659"
mRNA complement(616928..617170)
/gene="SSS1"
/locus_tag="YDR086C"
/product="Sss1p"
/transcript_id="NM_001180394.1"
/db_xref="GI:296143441"
/db_xref="GeneID:851659"
CDS complement(616928..617170)
/gene="SSS1"
/locus_tag="YDR086C"
/note="Subunit of the Sec61p translocation complex
(Sec61p-Sss1p-Sbh1p) that forms a channel for passage of
secretory proteins through the endoplasmic reticulum
membrane, and of the Ssh1p complex (Ssh1p-Sbh2p-Sss1p);
interacts with Ost4p and Wbp1p"
/codon_start=1
/product="Sss1p"
/protein_id="NP_010371.1"
/db_xref="GI:6320291"
/db_xref="SGD:S000002493"
/db_xref="GeneID:851659"
/translation="MARASEKGEEKKQSNNQVEKLVEAPVEFVREGTQFLAKCKKPDL
KEYTKIVKAVGIGFIAVGIIGYAIKLIHIPIRYVIV"
gene complement(617470..618306)
/gene="RRP1"
/locus_tag="YDR087C"
/db_xref="GeneID:851660"
mRNA complement(617470..618306)
/gene="RRP1"
/locus_tag="YDR087C"
/product="Rrp1p"
/transcript_id="NM_001180395.3"
/db_xref="GI:398365508"
/db_xref="GeneID:851660"
CDS complement(617470..618306)
/gene="RRP1"
/locus_tag="YDR087C"
/note="Essential evolutionarily conserved nucleolar
protein necessary for biogenesis of 60S ribosomal subunits
and processing of pre-rRNAs to mature rRNAs, associated
with several distinct 66S pre-ribosomal particles"
/codon_start=1
/product="Rrp1p"
/protein_id="NP_010372.3"
/db_xref="GI:398365509"
/db_xref="SGD:S000002494"
/db_xref="GeneID:851660"
/translation="METSNFVKQLSSNNRKTRVNALEALKKYLTAKQFKENKQIEFNK
LWKGLYYAMWFSDRPRPQQRLANELGELHGLYFDPKDNSTADELTTNDKAFIKFSRGF
WKVMCFEWFNIDRYRLDKYLLLIRRVLFSQLKYLQSRNWDKKLVDEYIKKVLRWLPLS
GSPKVYTGIPIHIVDILLDEWERLLKDGDEDDEDEENKEEEMRKIAESAKKTPLADVI
AIFQDIVADYNNSKVLREKIKEDLFSDTRLVSWDILEGETQHNDSSNESEEEEEEEWK
GF"
gene complement(618497..619645)
/gene="SLU7"
/locus_tag="YDR088C"
/gene_synonym="SLT17"
/db_xref="GeneID:851661"
mRNA complement(618497..619645)
/gene="SLU7"
/locus_tag="YDR088C"
/gene_synonym="SLT17"
/product="Slu7p"
/transcript_id="NM_001180396.3"
/db_xref="GI:398365514"
/db_xref="GeneID:851661"
CDS complement(618497..619645)
/gene="SLU7"
/locus_tag="YDR088C"
/gene_synonym="SLT17"
/note="RNA splicing factor, required for ATP-independent
portion of 2nd catalytic step of spliceosomal RNA
splicing; interacts with Prp18p; contains zinc knuckle
domain"
/codon_start=1
/product="Slu7p"
/protein_id="NP_010373.3"
/db_xref="GI:398365515"
/db_xref="SGD:S000002495"
/db_xref="GeneID:851661"
/translation="MNNNSRNNENRSTINRNKRQLQQAKEKNENIHIPRYIRNQPWYY
KDTPKEQEGKKPGNDDTSTAEGGEKSDYLVHHRQKAKGGALDIDNNSEPKIGMGIKDE
FKLIRPQKMSVRDSHSLSFCRNCGEAGHKEKDCMEKPRKMQKLVPDLNSQKNNGTVLV
RATDDDWDSRKDRWYGYSGKEYNELISKWERDKRNKIKGKDKSQTDETLWDTDEEIEL
MKLELYKDSVGSLKKDDADNSQLYRTSTRLREDKAAYLNDINSTESNYDPKSRLYKTE
TLGAVDEKSKMFRRHLTGEGLKLNELNQFARSHAKEMGIRDEIEDKEKVQHVLVANPT
KYEYLKKKREQEETKQPKIVSIGDLEARKVDGTKQSEEQRNHLKDLYG"
gene complement(619969..620041)
/locus_tag="tR(ACG)D"
/db_xref="GeneID:851662"
tRNA complement(619969..620041)
/locus_tag="tR(ACG)D"
/product="tRNA-Arg"
/note="Arginine tRNA (tRNA-Arg), predicted by tRNAscan-SE
analysis; one of 6 nuclear tRNA genes containing the
tDNA-anticodon ACG (converted to ICG in the mature tRNA),
decodes CGU, CGC, and probably CGA codons into arginine,
one of 19 nuclear tRNAs for arginine"
/db_xref="SGD:S000006700"
/db_xref="GeneID:851662"
gene 622112..624721
/locus_tag="YDR089W"
/db_xref="GeneID:851663"
mRNA 622112..624721
/locus_tag="YDR089W"
/product="hypothetical protein"
/transcript_id="NM_001180397.1"
/db_xref="GI:296143444"
/db_xref="GeneID:851663"
CDS 622112..624721
/locus_tag="YDR089W"
/note="hypothetical protein; deletion confers resistance
to nickel; contains an SPX domain, which is found in
proteins involved in phosphate homeostasis; relocalizes
from vacuole to cytoplasm upon DNA replication stress"
/codon_start=1
/product="hypothetical protein"
/protein_id="NP_010374.1"
/db_xref="GI:6320294"
/db_xref="SGD:S000002496"
/db_xref="GeneID:851663"
/translation="MKFEDRILNKSIPEWKFYNINYEKLKVAIKKVTAYDYDNPNDSG
MEKLLNQCSVAFDQEFQNVNLFVSLKIKEISTRILSVESSIIDFSKGLNKTSRNRFNL
RKLKIINAHVDDCNFELQLLSRFLIIQRIALRKLFKKLLNEFPQDSENPLTASEYVTS
IRNSESLRNGHEGISFMKLDLDPYLLEVSLIVDVLHDLENKLEDATEPAVEQRSLNRS
DESAHTSSSPEANNSSLPASPRSIPLLSNKKTSKMIDSSLEFDTALIDKAENLGRFLL
SSEDIEGLKFMLLNIGFRIIDDSIISTSKEILDTTDNINSAGNKSIRSAKSFNDLQHT
LSLSKQKNILPSAVQSNEKYVSISILDTVGNEGSPLLLTDDNINQHPNMIVSSTAEDT
CIVMCHVGGLRNHVVTNDLLLRDVKNILSAMRSGNDTKNISALINSLDPSPISKIALE
WIQSHRLKTIEPKLDFKRTRFISADNGDIYLIALDESITIGNVSTLPFPILEIKKLSR
SSGLSQTAINEDNKFKQLMKSVVTNEFQCSLIPPDLTTWKICLELVHSNELQNDLFQL
LLRDQYKLNSDDSLSPDEFFQLGKDRLEEEFDLTGPINNSQGSVDSGRRVRIHKKSKQ
SDNETKKKPIRYWNEFDEQEEDNLDNAFYIDTNGSRSTTDNEESLLLRNSPPDYGFIL
FSRNFINRTYDFCEKLRNLIRHDKKTSPDLFQNSKHPHCSSTNYGSVASFGSQSTSAS
YDDVQRYLQYQQQDIEDSQSIYEYRHDEVVTFLYLSALLTSCIMASVCLGIVLSLFRG
QSNNEIDLEIQNILIAIIIISLLVSLILICACLLLLFSRFTLAPIWHYVGCFTMFFSV
TGTVCYGMIEIFF"
gene complement(625066..625998)
/locus_tag="YDR090C"
/db_xref="GeneID:851664"
mRNA complement(625066..625998)
/locus_tag="YDR090C"
/product="hypothetical protein"
/transcript_id="NM_001180398.1"
/db_xref="GI:296143445"
/db_xref="GeneID:851664"
CDS complement(625066..625998)
/locus_tag="YDR090C"
/codon_start=1
/product="hypothetical protein"
/protein_id="NP_010375.1"
/db_xref="GI:6320295"
/db_xref="SGD:S000002497"
/db_xref="GeneID:851664"
/translation="MISEKAATALATIATVCWCVQLIPQIIYNWKKKDCTGLPPLMMF
LWVVSGIPFAIYFCVSKGNVILQVQPHLFMFFCSISFVQSCYYPPISMARSKIVMIVA
AIIAADVGMEVGFILWLRPLYEKGVKWPDLIFGISASVLLAVGLLPPYFELAKRKGRV
IGINFAFLFIDSLGAWLSIISVILGNMDIMGIILYSIVAGMELGIFASHFIWWCRFRF
LAKGNTFDEESGQAQKEEPDEKIEQDISKSDRNVTNYNLDNCSIPDDASSFADDFNIY
DSTDGGTLSRAQTLHAVHGVVVRTDPDRYSRLSV"
gene complement(626708..628534)
/gene="RLI1"
/locus_tag="YDR091C"
/db_xref="GeneID:851665"
mRNA complement(626708..628534)
/gene="RLI1"
/locus_tag="YDR091C"
/product="Rli1p"
/transcript_id="NM_001180399.3"
/db_xref="GI:398365536"
/db_xref="GeneID:851665"
CDS complement(626708..628534)
/gene="RLI1"
/locus_tag="YDR091C"
/note="Essential iron-sulfur protein required for ribosome
biogenesis and translation initiation and termination;
facilitates binding of a multifactor complex (MFC) of
initiation factors to the small ribosomal subunit;
predicted ABC family ATPase; forms a complex with Lto1p
and Yae1p that may be involved in protection of the
ribosome from damage due to reactive oxygen species"
/codon_start=1
/product="Rli1p"
/protein_id="NP_010376.3"
/db_xref="GI:398365537"
/db_xref="SGD:S000002498"
/db_xref="GeneID:851665"
/translation="MSDKNSRIAIVSADKCKPKKCRQECKRSCPVVKTGKLCIEVTPT
SKIAFISEILCIGCGICVKKCPFDAIQIINLPTNLEAHVTHRYSANSFKLHRLPTPRP
GQVLGLVGTNGIGKSTALKILAGKQKPNLGRFDDPPEWQEIIKYFRGSELQNYFTKML
EDDIKAIIKPQYVDNIPRAIKGPVQKVGELLKLRMEKSPEDVKRYIKILQLENVLKRD
IEKLSGGELQRFAIGMSCVQEADVYMFDEPSSYLDVKQRLNAAQIIRSLLAPTKYVIC
VEHDLSVLDYLSDFVCIIYGVPSVYGVVTLPASVREGINIFLDGHIPAENLRFRTEAL
QFRIADATEDLQNDSASRAFSYPSLKKTQGDFVLNVEEGEFSDSEILVMMGENGTGKT
TLIKLLAGALKPDEGQDIPKLNVSMKPQKIAPKFPGTVRQLFFKKIRGQFLNPQFQTD
VVKPLRIDDIIDQEVQHLSGGELQRVAIVLALGIPADIYLIDEPSAYLDSEQRIICSK
VIRRFILHNKKTAFIVEHDFIMATYLADKVIVFEGIPSKNAHARAPESLLTGCNRFLK
NLNVTFRRDPNSFRPRINKLDSQMDKEQKSSGNYFFLDNTGI"
rep_origin 628579..629921
/note="ARS420;
Putative replication origin, identified in multiple array
studies, not yet confirmed by plasmid-based assay"
/db_xref="SGD:S000130174"
gene 629876..630605
/gene="UBC13"
/locus_tag="YDR092W"
/db_xref="GeneID:851666"
mRNA join(629876..629905,630174..630605)
/gene="UBC13"
/locus_tag="YDR092W"
/product="E2 ubiquitin-conjugating protein UBC13"
/transcript_id="NM_001180400.3"
/db_xref="GI:398365540"
/db_xref="GeneID:851666"
CDS join(629876..629905,630174..630605)
/gene="UBC13"
/locus_tag="YDR092W"
/EC_number="6.3.2.19"
/note="Ubiquitin-conjugating enzyme involved in the
error-free DNA postreplication repair pathway; interacts
with Mms2p to assemble ubiquitin chains at the Ub Lys-63
residue; DNA damage triggers redistribution from the
cytoplasm to the nucleus"
/codon_start=1
/product="E2 ubiquitin-conjugating protein UBC13"
/protein_id="NP_010377.3"
/db_xref="GI:398365541"
/db_xref="SGD:S000002499"
/db_xref="GeneID:851666"
/translation="MASLPKRIIKETEKLVSDPVPGITAEPHDDNLRYFQVTIEGPEQ
SPYEDGIFELELYLPDDYPMEAPKVRFLTKIYHPNIDRLGRICLDVLKTNWSPALQIR
TVLLSIQALLASPNPNDPLANDVAEDWIKNEQGAKAKAREWTKLYAKKKPE"
gene 631282..636120
/gene="DNF2"
/locus_tag="YDR093W"
/db_xref="GeneID:851667"
mRNA 631282..636120
/gene="DNF2"
/locus_tag="YDR093W"
/product="aminophospholipid-translocating P4-type ATPase
DNF2"
/transcript_id="NM_001180401.1"
/db_xref="GI:296143448"
/db_xref="GeneID:851667"
CDS 631282..636120
/gene="DNF2"
/locus_tag="YDR093W"
/EC_number="3.6.3.1"
/note="Aminophospholipid translocase (flippase) that
localizes primarily to the plasma membrane; contributes to
endocytosis, protein transport and cell polarity; type 4
P-type ATPase"
/codon_start=1
/product="aminophospholipid-translocating P4-type ATPase
DNF2"
/protein_id="NP_010378.1"
/db_xref="GI:6320298"
/db_xref="SGD:S000002500"
/db_xref="GeneID:851667"
/translation="MSSPSKPTSPFVDDIEHESGSASNGLSSMSPFDDSFQFEKPSSA
HGNIEVAKTGGSVLKRQSKPMKDISTPDLSKVTFDGIDDYSNDNDINDDDELNGKKTE
IHEHENEVDDDLHSFQATPMPNTGGFEDVELDNNEGSNNDSQADHKLKRVRFGTRRNK
SGRIDINRSKTLKWAKKNFHNAIDEFSTKEDSLENSALQNRSDELRTVYYNLPLPEDM
LDEDGLPLAVYPRNKIRTTKYTPLTFFPKNILFQFHNFANIYFLILLILGAFQIFGVT
NPGFASVPLIVIVIITAIKDGIEDSRRTVLDLEVNNTRTHILSGVKNENVAVDNVSLW
RRFKKANTRALIKIFEYFSENLTAAGREKKLQKKREELRRKRNSRSFGPRGSLDSIGS
YRMSADFGRPSLDYENLNQTMSQANRYNDGENLVDRTLQPNPECRFAKDYWKNVKVGD
IVRVHNNDEIPADMILLSTSDVDGACYVETKNLDGETNLKVRQSLKCSKIIKSSRDIT
RTKFWVESEGPHANLYSYQGNFKWQDTQNGNIRNEPVNINNLLLRGCTLRNTKWAMGM
VIFTGDDTKIMINAGVTPTKKSRISRELNFSVILNFVLLFILCFTAGIVNGVYYKQKP
RSRDYFEFGTIGGSASTNGFVSFWVAVILYQSLVPISLYISVEIIKTAQAIFIYTDVL
LYNAKLDYPCTPKSWNISDDLGQIEYIFSDKTGTLTQNVMEFKKCTINGVSYGRAYTE
ALAGLRKRQGVDVESEGRREKEEIAKDRETMIDELRSMSDNTQFCPEDLTFVSKEIVE
DLKGSSGDHQQKCCEHFLLALALCHSVLVEPNKDDPKKLDIKAQSPDESALVSTARQL
GYSFVGSSKSGLIVEIQGVQKEFQVLNVLEFNSSRKRMSCIIKIPGSTPKDEPKALLI
CKGADSVIYSRLDRTQNDATLLEKTALHLEEYATEGLRTLCLAQRELTWSEYERWVKT
YDVAAASVTNREEELDKVTDVIERELILLGGTAIEDRLQDGVPDSIALLAEAGIKLWV
LTGDKVETAINIGFSCNVLNNDMELLVVKASGEDVEEFGSDPIQVVNNLVTKYLREKF
GMSGSEEELKEAKREHGLPQGNFAVIIDGDALKVALNGEEMRRKFLLLCKNCKAVLCC
RVSPAQKAAVVKLVKKTLDVMTLAIGDGSNDVAMIQSADVGVGIAGEEGRQAVMCSDY
AIGQFRYVTRLVLVHGKWCYKRLAEMIPQFFYKNVIFTLSLFWYGIYNNFDGSYLFEY
TYLTFYNLAFTSVPVILLAVLDQDVSDTVSMLVPQLYRVGILRKEWNQTKFLWYMLDG
VYQSVICFFFPYLAYHKNMVVTENGLGLDHRYFVGVFVTAIAVTSCNFYVFMEQYRWD
WFCGLFICLSLAVFYGWTGIWTSSSSSNEFYKGAARVFAQPAYWAVLFVGVLFCLLPR
FTIDCIRKIFYPKDIEIVREMWLRGDFDLYPQGYDPTDPSRPRINEIRPLTDFKEPIS
LDTHFDGVSHSQETIVTEEIPMSILNGEQGSRKGYRVSTTLERRDQLSPVTTTNNLPR
RSMASARGNKLRTSLDRTREEMLANHQLDTRYSVERARASLDLPGINHAETLLSQRSR
DR"
gene 637139..639823
/gene="GIS1"
/locus_tag="YDR096W"
/db_xref="GeneID:851670"
mRNA 637139..639823
/gene="GIS1"
/locus_tag="YDR096W"
/product="Gis1p"
/transcript_id="NM_001180404.1"
/db_xref="GI:296143449"
/db_xref="GeneID:851670"
CDS 637139..639823
/gene="GIS1"
/locus_tag="YDR096W"
/note="Histone demethylase and transcription factor;
regulates genes during nutrient limitation; negatively
regulates DPP1, PHR1; activity modulated by limited
proteasome-mediated proteolysis; has JmjC and JmjN domain
in N-terminal region that interact, promoting stability
and proper transcriptional activity; contains two
transactivating domains downstream of Jmj domains and a
C-terminal DNA binding domain; GIS1 has a paralog, RPH1,
that arose from the whole genome duplication"
/codon_start=1
/product="Gis1p"
/protein_id="NP_010381.1"
/db_xref="GI:6320301"
/db_xref="SGD:S000002503"
/db_xref="GeneID:851670"
/translation="MEIKPVEVIDGVPVFKPSMMEFANFQYFIDEITKFGIENGIVKV
IPPKEWLELLEGSPPAESLKTIQLDSPIQQQAKRWDKHENGVFSIENEYDNKSYNLTQ
WKNLAESLDSRISQGDFNDKTLKENCRVDSQQDCYDLAQLQILESDFWKTIAFSKPFY
AVDENSSIFPYDLTLWNLNNLPDSINSSNRRLLTGQSKCIFPWHLDEQNKCSINYLHF
GAPKQWYSIPSANTDQFLKILSKEPSSNKENCPAFIRHQNIITSPDFLRKNNIKFNRV
VQFQHEFIITFPYCMYSGFNYGYNFGESIEFILDQQAVVRKQPLKCGCGNKKEERKSG
PFSNLSYDSNESEQRGSITDNDNDLFQKVRSFDELLNHSSQELQNLEDNKNPLFSNIN
MNRPQSSSLRSTTPNGVNQFLNMNQTTISRISSPLLSRMMDLSNIVEPTLDDPGSKFK
RKVLTPQLPQMNIPSNSSNFGTPSLTNTNSLLSNITATSTNPSTTTNGSQNHNNVNAN
GINTSAAASINNNISSTNNSANNSSSNNNVSTVPSSMMHSSTLNGTSGLGGDNDDNML
ALSLATLANSATASPRLTLPPLSSPMNPNGHTSYNGNMMNNNSGNGSNGSNSYSNGVT
TAAATTTSAPHNLSIVSPNPTYSPNPLSLYLTNSKNPLNSGLAPLSPSTSNIPFLKRN
NVVTLNISREASKSPISSFVNDYRSPLGVSNPLMYSSTINDYSNGTGIRQNSNNINPL
DAGPSFSPLHKKPKILNGNDNSNLDSNNFDYSFTGNKQESNPSILNNNTNNNDNYRTS
SMNNNGNNYQAHSSKFGENEVIMSDHGKIYICRECNRQFSSGHHLTRHKKSVHSGEKP
HSCPRCGKRFKRRDHVLQHLNKKIPCTQEMENTKLAES"
rep_origin 639867..640115
/note="ARS421;
Autonomously Replicating Sequence"
/db_xref="SGD:S000118437"
gene complement(640109..643837)
/gene="MSH6"
/locus_tag="YDR097C"
/gene_synonym="PMS3"
/db_xref="GeneID:851671"
mRNA complement(640109..643837)
/gene="MSH6"
/locus_tag="YDR097C"
/gene_synonym="PMS3"
/product="mismatch repair ATPase MSH6"
/transcript_id="NM_001180405.3"
/db_xref="GI:398365558"
/db_xref="GeneID:851671"
CDS complement(640109..643837)
/gene="MSH6"
/locus_tag="YDR097C"
/gene_synonym="PMS3"
/note="Protein required for mismatch repair in mitosis and
meiosis, forms a complex with Msh2p to repair both
single-base & insertion-deletion mispairs; also involved
in interstrand cross-link repair; potentially
phosphorylated by Cdc28p"
/codon_start=1
/product="mismatch repair ATPase MSH6"
/protein_id="NP_010382.3"
/db_xref="GI:398365559"
/db_xref="SGD:S000002504"
/db_xref="GeneID:851671"
/translation="MAPATPKTSKTAHFENGSTSSQKKMKQSSLLSFFSKQVPSGTPS
KKVQKPTPATLENTATDKITKNPQGGKTGKLFVDVDEDNDLTIAEETVSTVRSDIMHS
QEPQSDTMLNSNTTEPKSTTTDEDLSSSQSRRNHKRRVNYAESDDDDSDTTFTAKRKK
GKVVDSESDEDEYLPDKNDGDEDDDIADDKEDIKGELAEDSGDDDDLISLAETTSKKK
FSYNTSHSSSPFTRNISRDNSKKKSRPNQAPSRSYNPSHSQPSATSKSSKFNKQNEER
YQWLVDERDAQRRPKSDPEYDPRTLYIPSSAWNKFTPFEKQYWEIKSKMWDCIVFFKK
GKFFELYEKDALLANALFDLKIAGGGRANMQLAGIPEMSFEYWAAQFIQMGYKVAKVD
QRESMLAKEMREGSKGIVKRELQCILTSGTLTDGDMLHSDLATFCLAIREEPGNFYNE
TQLDSSTIVQKLNTKIFGAAFIDTATGELQMLEFEDDSECTKLDTLMSQVRPMEVVME
RNNLSTLANKIVKFNSAPNAIFNEVKAGEEFYDCDKTYAEIISSEYFSTEEDWPEVLK
SYYDTGKKVGFSAFGGLLYYLKWLKLDKNLISMKNIKEYDFVKSQHSMVLDGITLQNL
EIFSNSFDGSDKGTLFKLFNRAITPMGKRMMKKWLMHPLLRKNDIESRLDSVDSLLQD
ITLREQLEITFSKLPDLERMLARIHSRTIKVKDFEKVITAFETIIELQDSLKNNDLKG
DVSKYISSFPEGLVEAVKSWTNAFERQKAINENIIVPQRGFDIEFDKSMDRIQELEDE
LMEILMTYRKQFKCSNIQYKDSGKEIYTIEIPISATKNVPSNWVQMAANKTYKRYYSD
EVRALARSMAEAKEIHKTLEEDLKNRLCQKFDAHYNTIWMPTIQAISNIDCLLAITRT
SEYLGAPSCRPTIVDEVDSKTNTQLNGFLKFKSLRHPCFNLGATTAKDFIPNDIELGK
EQPRLGLLTGANAAGKSTILRMACIAVIMAQMGCYVPCESAVLTPIDRIMTRLGANDN
IMQGKSTFFVELAETKKILDMATNRSLLVVDELGRGGSSSDGFAIAESVLHHVATHIQ
SLGFFATHYGTLASSFKHHPQVRPLKMSILVDEATRNVTFLYKMLEGQSEGSFGMHVA
SMCGISKEIIDNAQIAADNLEHTSRLVKERDLAANNLNGEVVSVPGGLQSDFVRIAYG
DGLKNTKLGSGEGVLNYDWNIKRNVLKSLFSIIDDLQS"
gene complement(644178..645035)
/gene="GRX3"
/locus_tag="YDR098C"
/db_xref="GeneID:851672"
mRNA complement(644178..645035)
/gene="GRX3"
/locus_tag="YDR098C"
/product="Grx3p"
/transcript_id="NM_001180406.3"
/db_xref="GI:398365572"
/db_xref="GeneID:851672"
CDS complement(644178..645035)
/gene="GRX3"
/locus_tag="YDR098C"
/note="Hydroperoxide and superoxide-radical responsive
glutathione-dependent oxidoreductase; monothiol
glutaredoxin subfamily member along with Grx4p and Grx5p;
protects cells from oxidative damage; evidence exists
indicating that the translation start site is not Met1 as
currently annotated, but rather Met36"
/codon_start=1
/product="Grx3p"
/protein_id="NP_010383.3"
/db_xref="GI:398365573"
/db_xref="SGD:S000002505"
/db_xref="GeneID:851672"
/translation="MCSFQVPSAFSFNYTSYCYKRHQARYYTAAKLFQEMPVIEINDQ
EQFTYLTTTAAGDKLIVLYFHTSWAEPCKALKQVFEAISNEPSNSNVSFLSIDADENS
EISELFEISAVPYFIIIHKGTILKELSGADPKEYVSLLEDCKNSVNSGSSQTHTMENA
NVNEGSHNDEDDDDEEEEEETEEQINARLTKLVNAAPVMLFMKGSPSEPKCGFSRQLV
GILREHQVRFGFFDILRDESVRQNLKKFSEWPTFPQLYINGEFQGGLDIIKESLEEDP
DFLQHALQS"
gene complement(645153..645224)
/locus_tag="tQ(UUG)D2"
/db_xref="GeneID:851673"
tRNA complement(645153..645224)
/locus_tag="tQ(UUG)D2"
/product="tRNA-Gln"
/note="Glutamine tRNA (tRNA-Gln), predicted by tRNAscan-SE
analysis; thiolation of uridine at wobble position (34)
requires Ncs6p"
/db_xref="SGD:S000006694"
/db_xref="GeneID:851673"
mobile_element complement(645502..651419)
/note="YDRCTy1-1; Ty1 element, LTR retrotransposon of the
Copia (Pseudoviridae) group; contains co-transcribed genes
TYA Gag and TYB Pol, encoding proteins involved in
structure and function of virus-like particles, flanked by
two direct repeats"
/mobile_element_type="retrotransposon:YDRCTy1-1"
/db_xref="SGD:S000006859"
LTR complement(645502..645835)
/note="Ty1 LTR"
/db_xref="SGD:S000006850"
gene complement(645858..651126)
/locus_tag="YDR098C-B"
/db_xref="GeneID:851674"
mRNA complement(join(<645858..649820,649822..>651126))
/locus_tag="YDR098C-B"
/transcript_id="NM_001184417.1"
/db_xref="GI:296143452"
/db_xref="GeneID:851674"
CDS complement(join(645858..649820,649822..651126))
/locus_tag="YDR098C-B"
/EC_number="2.7.7.49"
/EC_number="3.4.23.-"
/EC_number="3.1.26.4"
/EC_number="2.7.7.7"
/ribosomal_slippage
/note="Retrotransposon TYA Gag and TYB Pol genes;
transcribed/translated as one unit; polyprotein is
processed to make a nucleocapsid-like protein (Gag),
reverse transcriptase (RT), protease (PR), and integrase
(IN); similar to retroviral genes"
/codon_start=1
/product="gag-pol fusion protein"
/protein_id="NP_058140.1"
/db_xref="GI:7839152"
/db_xref="SGD:S000007391"
/db_xref="GeneID:851674"
/translation="MESQQLSNYPHISHGSACASVTSKEVHTNQDPLDVSASKIQEYD
KASTKANSQQTTTPASSAVPENPHHASPQPASVPPPQNGPYPQQCMMTQNQANPSGWS
FYGHPSMIPYTPYQMSPMYFPPGPQSQFPQYPSSVGTPLSTPSPESGNTFTDSSSADS
DMTSTKKYVRPPPMLTSPNDFPNWVKTYIKFLQNSNLGGIIPTVNGKPVRQITDDELT
FLYNTFQIFAPSQFLPTWVKDILSVDYTDIMKILSKSIEKMQSDTQEANDIVTLANLQ
YNGSTPADAFETKVTNIIDRLNNNGIHINNKVACQLIMRGLSGEYKFLRYTRHRHLNM
TVAELFLDIHAIYEEQQGSRNSKPNYRRNPSDEKNDSRSYTNTTKPKVIARNPQKTNN
SKSKTARAHNVSTSNNSPSTDNDSISKSTTEPIQLNNKHDLHLGQELTESTVNHTNHS
DDELPGHLLLDSGASRTLIRSAHHIHSASSNPGINVVDAQKRNIPINAIGDLQFHFQD
NTKTSIKVLHTPNIAYDLLSLNELAAVDITACFTKNVLERSDGTVLAPIVKYGDFYWV
SKKYLLPSNISVPTINNVHTSESTRKYPYPFIHRMLAHANAQTIRYSLKNNTITYFNE
SDVDWSSAIDYQCPDCLIGKSTKHRHIKGSRLKYQNSYEPFQYLHTDIFGPVHNLPNS
APSYFISFTDETTKFRWVYPLHDRREDSILDVFTTILAFIKNQFQASVLVIQMDRGSE
YTNRTLHKFLEKNGITPCYTTTADSRAHGVAERLNRTLLDDCRTQLQCSGLPNHLWFS
AIEFSTIVRNSLASPKSKKSARQHAGLAGLDISTLLPFGQPVIVNDHNPNSKIHPRGI
PGYALHPSRNSYGYIIYLPSLKKTVDTTNYVILQGKESRLDQFNYDALTFDEDLNRLT
ASYHSFIASNEIQESNDLNIESDHDFQSDIELHPEQPRNVLSKAVSPTDSTPPSTHTE
DSKRVSKTNIRAPREVDPNISESNILPSKKRSSTPQISNIESTGSGGMHKLNVPLLAP
MSQSNTHESSHASKSKDFRHSDSYSENETNHTNVPISSTGGTNNKTVPQISDQETEKR
IIHRSPSIDASPPENNSSHNIVPIKTPTTVSEQNTEESIIADLPLPDLPPESPTEFPD
PFKELPPINSHQTNSSLGGIGDSNAYTTINSKKRSLEDNETEIKVSRDTWNTKNMRSL
EPPRSKKRIHLIAAVKAVKSIKPIRTTLRYDEAITYNKDIKEKEKYIEAYHKEVNQLL
KMNTWDTDKYYDRKEIDPKRVINSMFIFNRKRDGTHKARFVARGDIQHPDTYDSGMQS
NTVHHYALMTSLSLALDNNYYITQLDISSAYLYADIKEELYIRPPPHLGMNDKLIRLK
KSLYGLKQSGANWYETIKSYLIKQCGMEEVRGWSCVFKNSQVTICLFVDDMILFSKDL
NANKKIITTLKKQYDTKIINLGEGDNEIQYDILGLEIKYQRSKYMKLGMEKSLTEKLP
KLNVPLNPKGKKLRAPGQPGHYIDQDELEIDEDEYKEKVHEMQKLIGLASYVGYKFRF
DLLYYINTLAQHILFPSRQVLDMTYELIQFMWDTRDKQLIWHKNKPTKPDNKLVAISD
ASYGNQPYYKSQIGNIFLLNGKVIGGKSTKASLTCTSTTEAEIHAVSEAIPLLNNLSH
LVQELNKKPIIKGSLTDSRSTISIIKSTNEEKFRNRFFGTKAMRLRDEVSGNNLYVYY
IETKKNIADVMTKPLPIKTFKLLTNKWIH"
gene complement(649804..651126)
/locus_tag="YDR098C-A"
/db_xref="GeneID:851675"
mRNA complement(<649804..>651126)
/locus_tag="YDR098C-A"
/transcript_id="NM_001184416.1"
/db_xref="GI:296143453"
/db_xref="GeneID:851675"
CDS complement(649804..651126)
/locus_tag="YDR098C-A"
/note="Retrotransposon TYA Gag gene co-transcribed with
TYB Pol; translated as TYA or TYA-TYB polyprotein; Gag is
a nucleocapsid protein that is the structural constituent
of virus-like particles (VLPs); similar to retroviral Gag"
/codon_start=1
/product="gag protein"
/protein_id="NP_058141.1"
/db_xref="GI:7839151"
/db_xref="SGD:S000007390"
/db_xref="GeneID:851675"
/translation="MESQQLSNYPHISHGSACASVTSKEVHTNQDPLDVSASKIQEYD
KASTKANSQQTTTPASSAVPENPHHASPQPASVPPPQNGPYPQQCMMTQNQANPSGWS
FYGHPSMIPYTPYQMSPMYFPPGPQSQFPQYPSSVGTPLSTPSPESGNTFTDSSSADS
DMTSTKKYVRPPPMLTSPNDFPNWVKTYIKFLQNSNLGGIIPTVNGKPVRQITDDELT
FLYNTFQIFAPSQFLPTWVKDILSVDYTDIMKILSKSIEKMQSDTQEANDIVTLANLQ
YNGSTPADAFETKVTNIIDRLNNNGIHINNKVACQLIMRGLSGEYKFLRYTRHRHLNM
TVAELFLDIHAIYEEQQGSRNSKPNYRRNPSDEKNDSRSYTNTTKPKVIARNPQKTNN
SKSKTARAHNVSTSNNSPSTDNDSISKSTTEPIQLNNKHDLHLRPGTY"
LTR complement(651086..651419)
/note="Ty1 LTR"
/db_xref="SGD:S000006851"
LTR complement(651420..651503)
/note="Ty3 LTR"
/db_xref="SGD:S000006855"
LTR complement(651682..651980)
/note="Ty1 LTR"
/db_xref="SGD:S000006852"
gene 653607..654428
/gene="BMH2"
/locus_tag="YDR099W"
/gene_synonym="SCD3"
/db_xref="GeneID:851676"
mRNA 653607..654428
/gene="BMH2"
/locus_tag="YDR099W"
/gene_synonym="SCD3"
/product="Bmh2p"
/transcript_id="NM_001180407.3"
/db_xref="GI:398365596"
/db_xref="GeneID:851676"
CDS 653607..654428
/gene="BMH2"
/locus_tag="YDR099W"
/gene_synonym="SCD3"
/note="14-3-3 protein, minor isoform; controls proteome at
post-transcriptional level, binds proteins and DNA,
involved in regulation of many processes including
exocytosis, vesicle transport, Ras/MAPK signaling, and
rapamycin-sensitive signaling; protein increases in
abundance and relative distribution to the nucleus
increases upon DNA replication stress"
/codon_start=1
/product="Bmh2p"
/protein_id="NP_010384.3"
/db_xref="GI:398365597"
/db_xref="SGD:S000002506"
/db_xref="GeneID:851676"
/translation="MSQTREDSVYLAKLAEQAERYEEMVENMKAVASSGQELSVEERN
LLSVAYKNVIGARRASWRIVSSIEQKEESKEKSEHQVELIRSYRSKIETELTKISDDI
LSVLDSHLIPSATTGESKVFYYKMKGDYHRYLAEFSSGDAREKATNSSLEAYKTASEI
ATTELPPTHPIRLGLALNFSVFYYEIQNSPDKACHLAKQAFDDAIAELDTLSEESYKD
STLIMQLLRDNLTLWTSDISESGQEDQQQQQQQQQQQQQQQQQAPAEQTQGEPTK"
gene 655013..655444
/gene="TVP15"
/locus_tag="YDR100W"
/db_xref="GeneID:851677"
mRNA 655013..655444
/gene="TVP15"
/locus_tag="YDR100W"
/product="Tvp15p"
/transcript_id="NM_001180408.3"
/db_xref="GI:398365600"
/db_xref="GeneID:851677"
CDS 655013..655444
/gene="TVP15"
/locus_tag="YDR100W"
/note="Integral membrane protein localized to late Golgi
vesicles along with the v-SNARE Tlg2p"
/codon_start=1
/product="Tvp15p"
/protein_id="NP_010385.3"
/db_xref="GI:398365601"
/db_xref="SGD:S000002507"
/db_xref="GeneID:851677"
/translation="MSVIPPKFFKIANISIGCIDIIAALSQLTYIFTNLNVFLLAVYG
LALSVPIVYLEFKVPSNLYRYASFYFSFLGRGLSYILLSLIISFGGIYNILAGMFTFI
LGVAFIVFHFSQFVEEPANFRAPGSSLSIGDDDIDDDDDMI"
gene complement(655686..657467)
/gene="ARX1"
/locus_tag="YDR101C"
/db_xref="GeneID:851678"
mRNA complement(655686..657467)
/gene="ARX1"
/locus_tag="YDR101C"
/product="Arx1p"
/transcript_id="NM_001180409.1"
/db_xref="GI:296143456"
/db_xref="GeneID:851678"
CDS complement(655686..657467)
/gene="ARX1"
/locus_tag="YDR101C"
/EC_number="3.-.-.-"
/note="Shuttling pre-60S factor; involved in the
biogenesis of ribosomal large subunit biogenesis;
interacts directly with Alb1; responsible for Tif6
recycling defects in absence of Rei1; associated with the
ribosomal export complex"
/codon_start=1
/product="Arx1p"
/protein_id="NP_010386.1"
/db_xref="GI:6320306"
/db_xref="SGD:S000002508"
/db_xref="GeneID:851678"
/translation="MALAISHEDTQILLKDKNILQESVLNKYRTAGQIAQTALKYVTS
LINDSYHSKTTQRQLTVPELCLLTDSFILTRLEQYYKNKVNERGIAIPTTIDIDQISG
GWCPEIDDTQNLLNWNKGKDSTFASSVTGTLRPGDLVKITLGVHIDGYTSEVSHTMVI
YPVDETKPILQPTGPLLGGKADAVAAAHIAMETVVALLACALTPEKLPASLGGTSSGI
TGQLIRTIVDTIARSYNCGVVPGSRVRRIRRFLAGQNEGIVAEREYKGVVWTESHQEA
DLLSNTDAKDLTVVDRGQSTPFTNVSAIPSDDFVVQSGEVYLIDLKMASLEHCTKKGL
VTLETVDSYTGKSHKAGELIARPGAYVRDFAQTHILKLKTSRQLLTKIDKQGVYPFKL
SHLSSNFPFVHENEEELQSLKKDLKSFRLGMSEISNNYLCVESPIQIARWVPWDHILK
ATNPNGNLSYDATSTLTLPGHELPLPKLGVSAIKLKSLMNSTKESISLPVARECNTIV
LCDSSVSTTDRPELLRLTGGSKTCQPSWIHSQHELNPQDSIVQGIFQLATLAKDKRFG
LLLKETQPMKQKSVETSNGGVEETMKM"
gene 658350..661103
/gene="STE5"
/locus_tag="YDR103W"
/gene_synonym="HMD3; NUL3"
/db_xref="GeneID:851680"
mRNA 658350..661103
/gene="STE5"
/locus_tag="YDR103W"
/gene_synonym="HMD3; NUL3"
/product="Ste5p"
/transcript_id="NM_001180411.1"
/db_xref="GI:296143457"
/db_xref="GeneID:851680"
CDS 658350..661103
/gene="STE5"
/locus_tag="YDR103W"
/gene_synonym="HMD3; NUL3"
/note="Pheromone-responsive MAPK scaffold protein; couples
activation of the G-protein-coupled pheromone receptor to
MAPK activation; intramolecular interaction of PH and VWA
domains blocks activation of assembled signaling cascade
components (Ste11p, Ste7p and Fus3p) under basal
conditions; Gbeta-gamma (Ste4p-Ste18p)-dependent docking
at the plasma membrane and binding of PI(4,5)P2 by the PH
domain relieves autoinhibition, resulting in
pheromone-dependent pathway activation"
/codon_start=1
/product="Ste5p"
/protein_id="NP_010388.1"
/db_xref="GI:6320308"
/db_xref="SGD:S000002510"
/db_xref="GeneID:851680"
/translation="MMETPTDNIVSPFHNFGSSTQYSGTLSRTPNQIIELEKPSTLSP
LSRGKKWTEKLARFQRSSAKKKRFSPSPISSSTFSFSPKSRVTSSNSSGNEDGNLMNT
PSTVSTDYLPQHPHRTSSLPRPNSNLFHASNSNLSRANEPPRAENLSDNIPPKVAPFG
YPIQRTSIKKSFLNASCTLCDEPISNRRKGEKIIELACGHLSHQECLIISFGTTSKAD
VRALFPFCTKCKKDTNKAVQCIPENDELKDILISDFLIHKIPDSELSITPQSRFPPYS
PLLPPFGLSYTPVERQTIYSQAPSLNPNLILAAPPKERNQIPQKKSNYTFLHSPLGHR
RIPSGANSILADTSVALSANDSISAVSNSVRAKDDETKTTLPLLRSYFIQILLNNFQE
ELQDWRIDGDYGLLRLVDKLMISKDGQRYIQCWCFLFEDAFVIAEVDNDVDVLEIRLK
NLEVFTPIANLRMTTLEASVLKCTLNKQHCADLSDLYIVQNINSDESTTVQKWISGIL
NQDFVFNEDNITSTLPILPIIKNFSKDVGNGRHETSTFLGLINPNKVVEVGNVHDNDT
VIIRRGFTLNSGECSRQSTVDSIQSVLTTISSILSLKREKPDNLAIILQIDFTKLKEE
DSLIVVYNSLKALTIKFARLQFCFVDRNNYVLDYGSVLHKIDSLDSISNLKSKSSSTQ
FSPIWLKNTLYPENIHEHLGIVAVSNSNMEAKKSILFQDYRCFTSFGRRRPNELKIKV
GYLNVDYSDKIDELVEASSWTFVLETLCYSFGLSFDEHDDDDEEDNDDSTDNELDNSS
GSLSDAESTTTIHIDSPFDNENATANMVNDRNLLTEGEHSNIENLETVASSVQPALIP
NIRFSLHSEEEGTNENENENDMPVLLLSDMDKGIDGITRRSSFSSLIESGNNNCPLHM
DYI"
gene complement(661173..664910)
/gene="SPO71"
/locus_tag="YDR104C"
/db_xref="GeneID:851681"
mRNA complement(661173..664910)
/gene="SPO71"
/locus_tag="YDR104C"
/product="Spo71p"
/transcript_id="NM_001180412.3"
/db_xref="GI:398365612"
/db_xref="GeneID:851681"
CDS complement(661173..664910)
/gene="SPO71"
/locus_tag="YDR104C"
/note="Meiosis-specific hypothetical protein, required for
spore wall formation during sporulation, in particular for
the proper size of the prospore membrane (PSM); interacts
with SPO1; dispensable for both nuclear divisions during
meiosis; contains two PH domains"
/codon_start=1
/product="Spo71p"
/protein_id="NP_010389.3"
/db_xref="GI:398365613"
/db_xref="SGD:S000002511"
/db_xref="GeneID:851681"
/translation="MDSIVNVVEDDVKYAQRVTSFSSPQNANVKVFTIPRHSFTAFRL
SYVSPTELSACSQVTLLGGIPKQWYADQNNQVWKLLTKISLRKVRKQSDMLRRYGYGT
IYKKRVGKIPTALYLRKHFTWSYEDNTSIHNGHRLKEAEMEMKRTRSSPVQKSEYKLS
LPRRCRSSSDQNFMRQELLKEKKSELSRNNSLPLIDTAQAVDIHPVLHEEDQENTNKR
NKSLLSNLKRKDLGESKSISRKDYSHFDRIPSPSSARSVGETDFNYNREPSEDTLRYP
DSIIEVTNRTSPAPNSILSRSGQFVNSNDLSDGFSTSNTINNVGLNANEKIFFNALQS
MEKENLMLWKTSQKYGTYLDERRKSADAFQKRERGSCVDIGKLHSSHLPFINILPPWP
TELTEEERIIHDRLASKHSHHIRKHVHNARNKTSCKIKDSVGTFLGMTNSLTNKATVK
KRTGQILKKEKMLVMVKEAIQNKVPLPNFSENECFDTRVSERWKEYIVIARSTGRFDP
PILLQFYRHRHIPEIEDISSIATKYHRNPLDFFLSRNCIVKFYSSLDKTISIQKPDKR
LGGFIDESIEKKDELKHYSPIKIFILRCSSIRSSGRWYKFLLESLDRQLFTPAINLKI
PLTEISIKINLNEIIFQKLIDLGKQEKDRLKICFLQRGYKIFQHPILRYFTVAILEKL
KLAHYDYLIRKWDTENPVLGCALKRYDRLEWIPCDEDSLVTGIFAFCQSHLIQYRPIA
NRLRETKSLEGKCLKEPTPIEGFLIRLTDKYGSARTNFGKYSISTAYFFTCENLLFSM
KAYRANPPLPIDSMIDDTSTEIEKEEIWKQWKKIPEVYEQQPYPLDTNDHIEWMNCQT
TQSEYDSRDFYAFHCFHRRIDQILKTDNVIDLTEVKDIYQGTRTDYEADKIKYGVYKE
ASEIFWHRNYEIDDVSRSVINIETSNGLLLKLLATSATVAEEWVIKLKQMISYWKNKQ
REDTERLLKIRRSNAGLLMLNGEEETKIGENTLRWIVEHGRADEQTFNANGISLSRPL
IQKGPLYQKPHKHSVFSKYYVVLISGFIVLFHCFHRSTTGFAKEVLEYAHYVTIPIDD
CYLYSGTTTELDLLQRDRTFDEINYGSHALPRVYGDGWRSVEDESSRCFTLWFGTRRA
LSSNRLQKKGNEKQYTQDYGRQDNNIDPPSAPEADLNNSNVPSNTDKIHFTKKLGVSG
KSMVFMARSRQERDLWVMSIYYELERLRRTASTSNSRNQTM"
gene complement(665349..666770)
/gene="TMS1"
/locus_tag="YDR105C"
/db_xref="GeneID:851682"
mRNA complement(665349..666770)
/gene="TMS1"
/locus_tag="YDR105C"
/product="Tms1p"
/transcript_id="NM_001180413.3"
/db_xref="GI:398365622"
/db_xref="GeneID:851682"
CDS complement(665349..666770)
/gene="TMS1"
/locus_tag="YDR105C"
/note="Vacuolar membrane hypothetical protein that is
conserved in mammals; predicted to contain eleven
transmembrane helices; interacts with Pdr5p, a protein
involved in multidrug resistance"
/codon_start=1
/product="Tms1p"
/protein_id="NP_010390.3"
/db_xref="GI:398365623"
/db_xref="SGD:S000002512"
/db_xref="GeneID:851682"
/translation="MGAVISLPVSMAGSFVASCFGGCCSNLVTKTASSLGSSSLGTRL
LYAVWLLLNSLISWVSYSANKSILWPGKTCTGTGECGFFTVHRLNFALGCLHLILALV
LTGVKSTNDVRAALQNSWWSLKFILYLCLIVLSFVIPNDFYIFFSKWVSVPSGAIFIL
VGLILLVDFAHEWAETCISHVESEDEDSSFWQRFLVLGTTSMYTASIIMTVVMYVMFC
HQQCNMNQTAVTVNLILTVITLVLSVNPKIQEANPKSGLAQSSMVSVYCTYLTMSAMS
SEPDDKMCNPLVRSSGTRKFSIILGSLFTFIAIAYTTTRAAANSAFQGTNTNGAIYLG
NDIEYEGLGGQTRNQLRYEAIKQAVEEGSLPESALYDTAWLGTSSPTGAMDNQNDDER
TGTKYNYTLFHVIFFLATQWIAILLTINVTQDDVGDFIPVGRTYFYSWVKIVSAWICY
ALYGWTVVAPAIMPDRFDYENYY"
gene 667004..667858
/gene="ARP10"
/locus_tag="YDR106W"
/db_xref="GeneID:851683"
mRNA 667004..667858
/gene="ARP10"
/locus_tag="YDR106W"
/product="Arp10p"
/transcript_id="NM_001180414.1"
/db_xref="GI:296143460"
/db_xref="GeneID:851683"
CDS 667004..667858
/gene="ARP10"
/locus_tag="YDR106W"
/note="Component of the dynactin complex, localized to the
pointed end of the Arp1p filament; may regulate membrane
association of the complex"
/codon_start=1
/product="Arp10p"
/protein_id="NP_010391.1"
/db_xref="GI:6320311"
/db_xref="SGD:S000002513"
/db_xref="GeneID:851683"
/translation="MSNTIVIVYLGANRIEIGRSADACPQEIIAWKTGSINEKNREEL
KKIFEHYFQICNILGNREVQVLILEDIFISVVEKRIICSILFKEFDCAHVSFVPRAIV
HCLSCNTRNAIVIDIGTNYTTCVPIFDLRPLQQFIKYSKRGKRQVESRIPLPGSLYMP
IFFDEEYNSKNCEVDETPVINLVKNIVESLPIDLRRPLRENIIIVNIEEAYETVIRNL
FKLKMDTSKIQFPKNYWQAGSACAKILLHYKGSNIVGIERDEFYNNPHIAPDWFDYYF
RTGVKRLQ"
gene complement(668007..668080)
/locus_tag="tI(AAU)D"
/db_xref="GeneID:851684"
tRNA complement(668007..668080)
/locus_tag="tI(AAU)D"
/product="tRNA-Ile"
/note="Isoleucine tRNA (tRNA-Ile), predicted by
tRNAscan-SE analysis"
/db_xref="SGD:S000006601"
/db_xref="GeneID:851684"
LTR 668096..668436
/note="Ty3 LTR"
/db_xref="SGD:S000006856"
LTR 668543..668784
/note="Ty1 LTR"
/db_xref="SGD:S000006864"
gene complement(669016..671034)
/gene="TMN2"
/locus_tag="YDR107C"
/db_xref="GeneID:851685"
mRNA complement(669016..671034)
/gene="TMN2"
/locus_tag="YDR107C"
/product="Tmn2p"
/transcript_id="NM_001180415.1"
/db_xref="GI:296143461"
/db_xref="GeneID:851685"
CDS complement(669016..671034)
/gene="TMN2"
/locus_tag="YDR107C"
/note="Protein with a role in cellular adhesion and
filamentous growth; similar to Emp70p and Tmn3p; member of
the evolutionarily conserved Transmembrane Nine family of
proteins with nine membrane-spanning segments"
/codon_start=1
/product="Tmn2p"
/protein_id="NP_010392.1"
/db_xref="GI:6320312"
/db_xref="SGD:S000002514"
/db_xref="GeneID:851685"
/translation="MKRGVWLLIYCYATLTKGFSLPGLSPTTYHSGDEIPLLVNRLTP
SIYFQHQDEEGNDVSGDKEHFLYSYDYYNKRFHFCRPEHVEKQPESLGSVIFGDRIYN
SPFQLNMLEEKECVALCKSTIPGKDAKFINTLIKSGFFQNWLVDGLPAARKAYDSRTK
TNYYGTGFELGFTDVKQTVDGKAVPSTMEELTSEASNEDVILDARLPKNVKPNLVKTV
ELPYFVNHFDIEVEFHDRGNDNYRVVGVIVNPVSIERSSPGACSTTGKPLILDEDKDN
EVYFTYSVKFVASDTVWATRWDKYLHIYDPQIQWFSLINFSVIVILLSSVVMHSLLRA
LKSDLARYNELNLDNEFHEDSGWKLGHGDVFRTPSKSMLLSILVGSGMQLFLMVMCSI
FFAAVGLVSPVSRGSLPTVMFVLYALFGFVGSYASMGVYKFFRGPYWKANMILTPILL
PGAIFLLIVIMNFFLLFAHSSGVIPARSLFFIILLWFLVSVPLSFAGSIVAHKQCNWD
EHPTKTNQIARQIPYQPWYLRTAQATLIAGIFSFGSIAVELYFIYSSLWFNKIFYMFG
FLLFSFLLLTLTTSLVTILITYYSLCLENWLWQWRSFIIGGLGCSIYTFIHSILFTKF
KLGGVITVVLYLGYSLIISALCCVVTGAIGFFSSMFFIRKIYSAIKVE"
gene 671269..673365
/gene="TRS85"
/locus_tag="YDR108W"
/gene_synonym="GSG1; MUM1"
/db_xref="GeneID:851686"
mRNA 671269..673365
/gene="TRS85"
/locus_tag="YDR108W"
/gene_synonym="GSG1; MUM1"
/product="Trs85p"
/transcript_id="NM_001180416.3"
/db_xref="GI:398365642"
/db_xref="GeneID:851686"
CDS 671269..673365
/gene="TRS85"
/locus_tag="YDR108W"
/gene_synonym="GSG1; MUM1"
/note="Subunit of TRAPPIII (transport protein particle), a
multimeric guanine nucleotide-exchange factor for Ypt1p,
required for membrane expansion during autophagy and the
CVT pathway; directs Ypt1p to the PAS; late
post-replication meiotic role"
/codon_start=1
/product="Trs85p"
/protein_id="NP_010393.3"
/db_xref="GI:398365643"
/db_xref="SGD:S000002515"
/db_xref="GeneID:851686"
/translation="MVFSYEHYMNLLFHLDNSKETVPPEIAKRIISNAIAPVITVTST
PLFDKHIQETYKVDSLYMLLRFFGGCVSDRDQANEAKVGQHEHEVCDASDSTDSIPKN
KNLEVPNLSKKGSRSRSNSLFQRDSTQSQYIRFTRPLGDLIETRDANDMLFNYHSLEV
FLDNYLKLVAANTDEMVPHNLLKKSIYHSFFSLAISSTNNLSPYETFNHPILSLIALD
ISNGEVYEDARDLLVNFKNLNHNTENFPIFMNTNEMLPVFLLCYNDDSQEEFEKCQAL
AKKLKKQLFVESILLALWKDSFIYDENSVIQLHQPVMSSLEEILFFLQAPTQTTLSLA
LINSIYDMLDYLVYDLMIPFMKRKVSFWEETILQPRKSLFNGAKFFKKFMNKNPVNGN
HQHNSLTRDSQGNEYFASSSSEFLMRKLADWSMMLSDFKTAYSTYESLMDDLDAFPKY
LASCIEWCAVSLLMGAQSIVTVKMIKNDINPLIERALATYENCSRIQRGKGKESNSLD
VTEPVRSYETRCMILASELFLSLSNTWTSTPYAIQYLETILDECKLGPCSQIMVWERL
SDCYNLRVDPRIKHRVGAMKKDAKDTEDLRGEHKYSTDHFTDEDILSEGLTRRRKAAF
FRLIAAKKWAEQKQWRQVSWCLKDIESTYSEIKFLHGNGLILSKLKNQLNLKDVDSAP
RPSEKNLTRTSVSFIG"
gene complement(673520..675667)
/locus_tag="YDR109C"
/db_xref="GeneID:851687"
mRNA complement(673520..675667)
/locus_tag="YDR109C"
/product="putative phosphotransferase"
/transcript_id="NM_001180417.3"
/db_xref="GI:398365648"
/db_xref="GeneID:851687"
CDS complement(673520..675667)
/locus_tag="YDR109C"
/EC_number="2.7.1.-"
/note="Putative kinase"
/codon_start=1
/product="putative phosphotransferase"
/protein_id="NP_010394.3"
/db_xref="GI:398365649"
/db_xref="SGD:S000002516"
/db_xref="GeneID:851687"
/translation="MKSRKRQNNMQNETREPAVLSSQETSISRISPQDPEAKFYVGVD
VGTGSARACVIDQSGNMLSLAEKPIKREQLISNFITQSSREIWNAVCYCVRTVVEESG
VDPERVRGIGFDATCSLVVVSATNFEEIAVGPDFTNNDQNIILWMDHRAMKETEEINS
SGDKCLKYVGGQMSVEMEIPKIKWLKNNLEAGIFQDCKFFDLPDYLTFKATGKENRSF
CSAVCKQGFLPVGVEGSDIGWSKEFLNSIGLSELTKNDFERLGGSLREKKNFLTAGEC
ISPLDKKAACQLGLTEHCVVSSGIIDAYAGWVGTVAAKPESAVKGLAETENYKKDFNG
AIGRLAAVAGTSTCHILLSKNPIFVHGVWGPYRDVLARGFWAAEGGQSCTGVLLDHLI
TTHPAFTELSHMANLAGVSKFEYLNKILETLVEKRKVRSVISLAKHLFFYGDYHGNRS
PIADPNMRACIIGQSMDNSIEDLAVMYLSACEFISQQTRQIIEVMLKSGHEINAIFMS
GGQCRNSLLMRLLADCTGLPIVIPRYVDAAVVFGSALLGAAASEDFDYTREKRTLKGQ
KSSQTKTERFNDSYSSIQKLSMEDRNSTNGFVSPHNLQLSTPSAPAKINNYSLPICTQ
QPLDKTSEESSKDASLTVGQESLGEGRYNGTSFLWKVMQELTGNARIVNPNEKTHPDR
ILLDTKYQIFLDMIETQRKYRRMVDKVEGSFSR"
gene 676102..677802
/gene="FOB1"
/locus_tag="YDR110W"
/gene_synonym="HRM1"
/db_xref="GeneID:851688"
mRNA 676102..677802
/gene="FOB1"
/locus_tag="YDR110W"
/gene_synonym="HRM1"
/product="Fob1p"
/transcript_id="NM_001180418.1"
/db_xref="GI:296143464"
/db_xref="GeneID:851688"
CDS 676102..677802
/gene="FOB1"
/locus_tag="YDR110W"
/gene_synonym="HRM1"
/note="Nucleolar protein that binds the rDNA replication
fork barrier (RFB) site; required for replication fork
blocking, recombinational hotspot activity, condensin
recruitment to RFB and rDNA repeat segregation; related to
retroviral integrases"
/codon_start=1
/product="Fob1p"
/protein_id="NP_010395.1"
/db_xref="GI:6320315"
/db_xref="SGD:S000002517"
/db_xref="GeneID:851688"
/translation="MTKPRYNDVLFDDDDSVPSESVTRKSQRRKATSPGESRESSKDR
LLILPSMGESYTEYVDSYLNLELLERGERETPIFLESLTRQLTQKIYELIKTKSLTAD
TLQQISDKYDGVVAENKLLFLQRQYYVDDEGNVRDGRNNDKIYCEPKHVYDMVMATHL
MNKHLRGKTLHSFLFSHFANISHAIIDWVQQFCSKCNKKGKIKPLKEYKRPDMYDKLL
PMERIHIEVFEPFNGEAIEGKYSYVLLCRDYRSSFMWLLPLKSTKFKHLIPVVSSLFL
TFARVPIFVTSSTLDKDDLYDICEEIASKYGLRIGLGLKSSARFHTGGILCIQYALNS
YKKECLADWGKCLRYGPYRFNRRRNKRTKRKPVQVLLSEVPGHNAKFETKRERVIENT
YSRNMFKMAGGKGLIYLEDVNTFALANEADNSCNNNGILHNNNIGNDNFEEEVQKQFD
LTEKNYIDEYDDLAHDSSEGEFEPNTLTPEEKPPHNVDEDRIESTGVAAPMQGTEEPE
KGDQKESDGASQVDQSVEITRPETSYYQTLESPSTKRQKLDQQGNGDQTRDFGTSMEL
"
gene complement(678241..679764)
/gene="ALT2"
/locus_tag="YDR111C"
/db_xref="GeneID:851690"
mRNA complement(678241..679764)
/gene="ALT2"
/locus_tag="YDR111C"
/product="alanine transaminase ALT2"
/transcript_id="NM_001180419.1"
/db_xref="GI:296143465"
/db_xref="GeneID:851690"
CDS complement(678241..679764)
/gene="ALT2"
/locus_tag="YDR111C"
/EC_number="2.6.1.2"
/note="Catalytically inactive paralog of ALT1, an alanine
transaminase; expression is repressed in the presence of
alanine and repression is mediated by Nrg1p"
/codon_start=1
/product="alanine transaminase ALT2"
/protein_id="NP_010396.1"
/db_xref="GI:6320317"
/db_xref="SGD:S000002518"
/db_xref="GeneID:851690"
/translation="MTMTHQQDLKGVFTAKDLDFKPAGKITKKDLNTGVTKAEYAVRG
AIPTRADELKEELKKNPEVLPFDDIINANIGNPQQLDQKPLTFTRQVLAILEYPEILR
VGHNELASLNLFSRDALERAERLLNDIGGSIGAYSHSQGVPGIRQTVADFITRRDGGE
PATPEDIYLTTGASSAATSLLSLLCKDSQTGLLIPIPQYPLYTASASLFNAQVLPYYL
DEESNWSTNSDEIEKVVQDALKKQIRPSVLIVINPGNPTGAVLSEETIARICLIAAKY
GITIISDEVYQENIFNDVKFHSMKKVLRKLQHLYPGKFDNVQLASLHSISKGFMDECG
QRGGYMEIIGFSQEIRDALFKLMSISICSVVTGQAVVDLMVKPPQPGDESYEQDHDER
LKIFHEMRTRANLLYETFKELEGIECQKPQGAMYLFPRLVLPKKALCESERLGIEPDE
FYCTSLLESTGICTVPGSGFGQRPGTYHVRTTFLAPGTKWIQDWKEFHQDFFSKYRN"
gene complement(680496..681617)
/gene="PDS1"
/locus_tag="YDR113C"
/db_xref="GeneID:851691"
mRNA complement(680496..681617)
/gene="PDS1"
/locus_tag="YDR113C"
/product="Pds1p"
/transcript_id="NM_001180421.3"
/db_xref="GI:398365666"
/db_xref="GeneID:851691"
CDS complement(680496..681617)
/gene="PDS1"
/locus_tag="YDR113C"
/note="Securin, inhibits anaphase by binding separin
Esp1p; blocks cyclin destruction and mitotic exit,
essential for meiotic progression and mitotic cell cycle
arrest; localization is cell-cycle dependent and regulated
by Cdc28p phosphorylation"
/codon_start=1
/product="Pds1p"
/protein_id="NP_010398.3"
/db_xref="GI:398365667"
/db_xref="SGD:S000002520"
/db_xref="GeneID:851691"
/translation="MMPANEDKENNIVYTGNESSGINFPQTPAHLLKRSHSNILKPPV
RLDQLKRDANSNNGNTLKYIQGGKEVSPTKRLHTHAQQQGRLPLAAKDNNRSKSFIFP
ETSNQSKDADLPQLQNTLSIRKNDQLRKLSQISRSRSRANHNDLLSNSRKLQKYGSVL
GYNALPKMKSLVLKDLADSGKNEESSDDDEGNEDSESKLGKKLQSALLKQDSSDGENE
LNGGLGLFNEQGGLQQLIKNSTKNEQKTKNDKSDKTDDYDIEIAPQRQEPLPYVPEGY
SPFQQDDIEKLKTFNSPYKLDLEDEDDTPDKVDLLPLEQIDEEGEKDETECITRNQEE
GAALPLLSKNFKEVAAVPTMELVYSEEGLDPEELEDLVT"
gene complement(681924..682226)
/locus_tag="YDR114C"
/db_xref="GeneID:851693"
mRNA complement(681924..682226)
/locus_tag="YDR114C"
/product="hypothetical protein"
/transcript_id="NM_001180422.3"
/db_xref="GI:398365672"
/db_xref="GeneID:851693"
CDS complement(681924..682226)
/locus_tag="YDR114C"
/note="hypothetical protein; deletion mutant exhibits poor
growth at elevated pH and calcium"
/codon_start=1
/product="hypothetical protein"
/protein_id="NP_010399.3"
/db_xref="GI:398365673"
/db_xref="SGD:S000002521"
/db_xref="GeneID:851693"
/translation="MKTFFLIEAGRALQIVAFRPAITTVLFQRFSVSFSCSYFTCCTS
QLLRENWLFKFLTAFDHVIRASNDLSTMRFMIMYIYVYIYIYTVLRKRLSCYMLIL"
gene 682175..682492
/locus_tag="YDR115W"
/db_xref="GeneID:851692"
mRNA 682175..682492
/locus_tag="YDR115W"
/product="putative mitochondrial 54S ribosomal protein"
/transcript_id="NM_001180423.1"
/db_xref="GI:296143468"
/db_xref="GeneID:851692"
CDS 682175..682492
/locus_tag="YDR115W"
/note="Putative mitochondrial ribosomal protein of the
large subunit; has similarity to E. coli L34 ribosomal
protein; required for respiratory growth, as are most
mitochondrial ribosomal proteins; protein increases in
abundance and relocalizes to the plasma membrane upon DNA
replication stress"
/codon_start=1
/product="putative mitochondrial 54S ribosomal protein"
/protein_id="NP_010400.1"
/db_xref="GI:6320319"
/db_xref="SGD:S000002522"
/db_xref="GeneID:851692"
/translation="MPLFARLCQPQSRRMFSSISSFSALSVLRPQTGMLLNSSPLKTP
SFTPLGFGLIGQRRWKSRGNTYQPSTLKRKRTFGFLARAKSKQGSKILKRRKLKGRWF
LSH"
gene complement(682724..683581)
/gene="MRPL1"
/locus_tag="YDR116C"
/db_xref="GeneID:851694"
mRNA complement(682724..683581)
/gene="MRPL1"
/locus_tag="YDR116C"
/product="mitochondrial 54S ribosomal protein MRPL1"
/transcript_id="NM_001180424.1"
/db_xref="GI:296143469"
/db_xref="GeneID:851694"
CDS complement(682724..683581)
/gene="MRPL1"
/locus_tag="YDR116C"
/note="Mitochondrial ribosomal protein of the large
subunit"
/codon_start=1
/product="mitochondrial 54S ribosomal protein MRPL1"
/protein_id="NP_010401.1"
/db_xref="GI:6320321"
/db_xref="SGD:S000002523"
/db_xref="GeneID:851694"
/translation="MLSVVAIPKICVTGPARRCFFHTAKKLYADDYKPAAMSSNAPSL
TKDQAKKRELKRLVQRKAEAKRPATASPLYMPVTKALRYLRAAEVGRPQSQQTINLTT
LVVGERGTAPLSGSVTFPKPLRYIKIAAFTNDESKLEELREKYPNHLIGGADLVAKIK
SGEISVDFDKAFATPDIVPALQSQVARILGPRGVLPSVKKGTVSDDISSLLQESLGSM
PFRQRGNSISIGVGKCYFTDREILQNIISARAAFKTAVDNQKSKKPNILSKTTLSSTH
GPGIVIDFA"
gene complement(683946..685643)
/gene="TMA64"
/locus_tag="YDR117C"
/db_xref="GeneID:851695"
mRNA complement(683946..685643)
/gene="TMA64"
/locus_tag="YDR117C"
/product="Tma64p"
/transcript_id="NM_001180425.3"
/db_xref="GI:398365692"
/db_xref="GeneID:851695"
CDS complement(683946..685643)
/gene="TMA64"
/locus_tag="YDR117C"
/note="hypothetical protein that associates with
ribosomes; has a putative RNA binding domain; in mammals
the corresponding protein, eIF2D, has been shown to
possess translation initiation factor activity"
/codon_start=1
/product="Tma64p"
/protein_id="NP_010402.3"
/db_xref="GI:398365693"
/db_xref="SGD:S000002524"
/db_xref="GeneID:851695"
/translation="MFKKEPHIKALSNLKNSERKKLLQTFQKQTNNEEYSFRTSTIKQ
TNFNGQKSVGTVYTDENNTPILFKEKHKEQLFPTVYSCWEYPALLPIVLTHGFVIEEH
LFNGANLMISGSIPPFDPRCKIGTLCGIASKQAPETVLAIGIVELDLPSFDKVIGETG
VAVKIIHHFNDGLSKVFKMKLEPPFVLSTQSKDNNISSKQIESSEQIKAVEKEQEDVK
EASVDVEEIAEVLDHFTVSDVDYFITRALYYTLTQDKGLELPISASNFISNHIMRNLP
PIDHNEVNVKKTSWKKSAKFLKHFEKEGFLKLKGKGDDLTIVGKNTDKDELKNFVPYK
LGCSKSATESRESTTSKEKTSGMMYSLTLYKPFNLAKDLLKEVNLASHTYYTSQDIRS
AVSQYISVKNLADTKDKGKVIMDDLLFDMVNKKKKVLNASRIIARGEILHPLLTNNFT
EFYQIFKSDDTLLFKAPMKGSLPHIKIITEMKIGRKVITRVSNFEVFQVDPESLAADL
RKICSGSTTISESQTFKCAEVQVQGPHGQSIIDHLNKLGIPSKWIDFENKLKKKKRK"
gene 685882..687840
/gene="APC4"
/locus_tag="YDR118W"
/db_xref="GeneID:851696"
mRNA 685882..687840
/gene="APC4"
/locus_tag="YDR118W"
/product="anaphase promoting complex subunit 4"
/transcript_id="NM_001180426.3"
/db_xref="GI:398365698"
/db_xref="GeneID:851696"
CDS 685882..687840
/gene="APC4"
/locus_tag="YDR118W"
/note="Subunit of the Anaphase-Promoting Complex/Cyclosome
(APC/C); APC/C is a ubiquitin-protein ligase required for
degradation of anaphase inhibitors, including mitotic
cyclins, during the metaphase/anaphase transition;
component of the platform domain of the APC/C, based on
structural analysis; relative distribution to the nucleus
increases upon DNA replication stress"
/codon_start=1
/product="anaphase promoting complex subunit 4"
/protein_id="NP_010403.3"
/db_xref="GI:398365699"
/db_xref="SGD:S000002525"
/db_xref="GeneID:851696"
/translation="MSSPINDYFIDYNPLFPIFATRIAKGLAIYRVSDHARLAVIPIR
NINLVANYDWDTTTGKFLSIFFKDGTIRIHDIFKDGRLVSFLRIPSTKISKGIWDRIP
LRYEPNNRDFACNIIDDLPKLIRFVKDSKRINIVPYTQPNSLWRGPDEDDLDSNEKLD
VHVVFNEGNDKITVFFNGDYAVFLSVDNIENENSLKSIIKVQDGFYQCFYEDGTVQTL
NLGPLLQSKSSVNLLNYIMVIKELIGYMLTHLEFINRELATPYLDFVKRLCDEAYGYG
KLKSELEALFLLGEISCDLEDWLCNSVGEKNFKRWKYLGCEAYQKTVQILTLIFVPAC
ERIIIYVEKLRAILQAFSIQNKLSYTSDLTAVEVLLKSSQKLLTMTLNSIIGLGRDET
LFEKFFIWFNDRLHEALDEDYKLKFQFEDDLYFGYDLLSYFDRILSKKGTEPSSIIDV
KLYRDLINSMSDMEKDIAQSNVNSHIQQHILVDLKTDVFAQKYPSSQINLLDAIKLPK
HNYIVYLIQVTKHNSAQEPFSEENKKKLYIGTLKDENLGIISKESSVKIPALFKSYRL
SSTRFVPNRVHSLLRDIGLSDSNYHSSHVTDYRGENYENEEDDGTIAIPAYIRENREN
DDFIACTAKVSVDGRSASLVFPKEKQNV"
gene 688227..690533
/gene="VBA4"
/locus_tag="YDR119W"
/db_xref="GeneID:851697"
mRNA 688227..690533
/gene="VBA4"
/locus_tag="YDR119W"
/product="Vba4p"
/transcript_id="NM_001180427.1"
/db_xref="GI:296143472"
/db_xref="GeneID:851697"
CDS 688227..690533
/gene="VBA4"
/locus_tag="YDR119W"
/note="hypothetical protein with proposed role as a basic
amino acid permease based on phylogeny; GFP-fusion protein
localizes to vacuolar membrane; physical interaction with
Atg27p suggests a possible role in autophagy;
non-essential gene"
/codon_start=1
/product="Vba4p"
/protein_id="NP_010404.1"
/db_xref="GI:6320324"
/db_xref="SGD:S000002526"
/db_xref="GeneID:851697"
/translation="MGKKDRQRKKLREFAKLKNRQRNLRKSVQTLKNEVQREAKVPRT
SNQIALGNDKIEEINENSPLLSAPSKQEEVSIPKAVDIDTIDAQPLHEGPKIDDSPQD
EVNSIKGKPADKANEDDLKPPSQHEACGNSALQSSITDFSDRSVSPLQSITSCNTPMS
EHELPVSSSNSFERADDMPVVQADNQTSSSKSLHIVAPSPEVPVSGDEITSYGYGSIP
QSIGDVENGLNPPYVENTSSDELVHDLTRRRIFSSCMCTYLFFIAMDSSIILVIASKI
ASEFHELWRLSLVISAYLLSNAIGQLVFLKLSLISSVKLLLCIAQFSFILGGYLSWSS
AHFWTFIFARCVTGFGGGSLIALKSTIMNRFSQKNDSRYSLSASMITFAMGVVIGPFM
MNLFDSSHGSGWRNAFLIPVPFCLVNASIMLADMYSVKSTLYGRPTPTLWKRFKNTLL
SPDLYEILTLTLFLLCFVQVTSLDLTGLKNNTMIQALLFSVIIVCGILFFLIETSDTY
MNSVISMSLQGDKRLIWTMIGISFCFAALMCIIPFGTTYFIIVLNLSTLQLAERLSPF
FFSIVLGYFSVSYFWKSKGQNFLLKFVLSGATLLLYVALMGVSLNLPVWKQYICLSLP
FLGSSMILTLLSNLYHEYHEQRKSPISGSIVYCFGAVGGTVGISLGGYVFHKTLIKLM
HEKVMPFSKQGYLKKDLLKIIKHATESSDWVHESAPKFVFQTLIECYLQACRNVFKLS
TLFFTITVVAIFIFNRIHCRSQNCLSLS"
gene 691014..691214
/gene="COX26"
/locus_tag="YDR119W-A"
/db_xref="GeneID:3799970"
mRNA 691014..691214
/gene="COX26"
/locus_tag="YDR119W-A"
/product="Cox26p"
/transcript_id="NM_001184681.1"
/db_xref="GI:296143473"
/db_xref="GeneID:3799970"
CDS 691014..691214
/gene="COX26"
/locus_tag="YDR119W-A"
/note="hypothetical protein; copurifies with respiratory
chain supercomplexes composed of Complex III
(ubiquinol-cytochrome c reductase) and Complex IV
(cytochrome c oxidase)"
/codon_start=1
/product="Cox26p"
/protein_id="NP_001032575.1"
/db_xref="GI:82795245"
/db_xref="SGD:S000113555"
/db_xref="GeneID:3799970"
/translation="MFFSQVLRSSARAAPIKRYTGGRIGESWVITEGRRLIPEIFQWS
AVLSVCLGWPGAVYFFSKARKA"
gene complement(691549..693261)
/gene="TRM1"
/locus_tag="YDR120C"
/db_xref="GeneID:851698"
mRNA complement(691549..693261)
/gene="TRM1"
/locus_tag="YDR120C"
/product="Trm1p"
/transcript_id="NM_001180428.3"
/db_xref="GI:398365716"
/db_xref="GeneID:851698"
CDS complement(691549..693261)
/gene="TRM1"
/locus_tag="YDR120C"
/note="tRNA methyltransferase; two forms of the protein
are made by alternative translation starts; localizes to
both the nucleus and mitochondrion to produce the modified
base N2,N2-dimethylguanosine in tRNAs in both
compartments"
/codon_start=1
/product="Trm1p"
/protein_id="NP_010405.3"
/db_xref="GI:398365717"
/db_xref="SGD:S000002527"
/db_xref="GeneID:851698"
/translation="MEGFFRIPLKRANLHGMLKAAISKIKANFTAYGAPRINIEDFNI
VKEGKAEILFPKKETVFYNPIQQFNRDLSVTCIKAWDNLYGEECGQKRNNKKSKKKRC
AETNDDSSKRQKMGNGSPKEAVGNSNRNEPYINILEALSATGLRAIRYAHEIPHVREV
IANDLLPEAVESIKRNVEYNSVENIVKPNLDDANVLMYRNKATNNKFHVIDLDPYGTV
TPFVDAAIQSIEEGGLMLVTCTDLSVLAGNGYPEKCFALYGGANMVSHESTHESALRL
VLNLLKQTAAKYKKTVEPLLSLSIDFYVRVFVKVKTSPIEVKNVMSSTMTTYHCSRCG
SYHNQPLGRISQREGRNNKTFTKYSVAQGPPVDTKCKFCEGTYHLAGPMYAGPLHNKE
FIEEVLRINKEEHRDQDDTYGTRKRIEGMLSLAKNELSDSPFYFSPNHIASVIKLQVP
PLKKVVAGLGSLGFECSLTHAQPSSLKTNAPWDAIWYVMQKCDDEKKDLSKMNPNTTG
YKILSAMPGWLSGTVKSEYDSKLSFAPNEQSGNIEKLRKLKIVRYQENPTKNWGPKAR
PNTS"
gene 693585..694175
/gene="DPB4"
/locus_tag="YDR121W"
/db_xref="GeneID:851699"
mRNA 693585..694175
/gene="DPB4"
/locus_tag="YDR121W"
/product="Dpb4p"
/transcript_id="NM_001180429.3"
/db_xref="GI:398365722"
/db_xref="GeneID:851699"
CDS 693585..694175
/gene="DPB4"
/locus_tag="YDR121W"
/EC_number="2.7.7.7"
/note="Subunit of DNA pol epsilon and of ISW2 chromatin
accessibility complex; involved in both chromosomal DNA
replication and inheritance of telomeric silencing;
stabilizes the interaction of Pol epsilon with
primer-template DNA, positively affecting the processivity
of the polymerase and exonuclease activities of Pol
epsilon; interacts with extranucleosomal DNA and acts as
anchor point for ISW2 complex that retains its position on
DNA during nucleosome mobilization"
/codon_start=1
/product="Dpb4p"
/protein_id="NP_010406.3"
/db_xref="GI:398365723"
/db_xref="SGD:S000002528"
/db_xref="GeneID:851699"
/translation="MPPKGWRKDAQGNYPTTSYIKEQENITIQDLLFPKSTIVNLARE
VPQQSGKKLLINKDASLALQRGATVFVNHLLLFAREIAKSQDKKSCSVDDVLSALDHI
GHSALKGPVRDKLDEYQAAVEQRKKEKLDSGEVDADGDIDMGEDKENVPVEKVKEHDE
IEEQGDALQDVEESSEKKQKTESQDVETRVQNLEQT"
gene 694700..697894
/gene="KIN1"
/locus_tag="YDR122W"
/db_xref="GeneID:851700"
mRNA 694700..697894
/gene="KIN1"
/locus_tag="YDR122W"
/product="Kin1p"
/transcript_id="NM_001180430.1"
/db_xref="GI:296143476"
/db_xref="GeneID:851700"
CDS 694700..697894
/gene="KIN1"
/locus_tag="YDR122W"
/EC_number="2.7.11.1"
/note="Serine/threonine protein kinase involved in
regulation of exocytosis; localizes to the cytoplasmic
face of the plasma membrane; closely related to Kin2p"
/codon_start=1
/product="Kin1p"
/protein_id="NP_010407.1"
/db_xref="GI:6320327"
/db_xref="SGD:S000002529"
/db_xref="GeneID:851700"
/translation="MDDYHVNTAFSMGRGNQQDDGNSESNSMHTQPSTMAPATLRMMG
KSPQQQQQQNTPLMPPADIKYANNGNSHQAEQKERQVELEGKSRENAPKPNTTSQSRV
SSSQGMPKQFHRKSLGDWEFVETVGAGSMGKVKLAKHRYTNEVCAVKIVNRATKAFLH
KEQMLPPPKNEQDVLERQKKLEKEISRDKRTIREASLGQILYHPHICRLFEMCTLSNH
FYMLFEYVSGGQLLDYIIQHGSIREHQARKFARGIASALIYLHANNIVHRDLKIENIM
ISDSSEIKIIDFGLSNIYDSRKQLHTFCGSLYFAAPELLKANPYTGPEVDVWSFGVVL
FVLVCGKVPFDDENSSVLHEKIKQGKVEYPQHLSIEVISLLSKMLVVDPKRRATLKQV
VEHHWMVRGFNGPPPSYLPKRVPLTIEMLDINVLKEMYRLEFIDDVEETRSVLVSIIT
DPTYVLLSRQYWTLAAKMNAESSDNGNAPNITESFEDPTRAYHPMISIYYLTSEMLDR
KHAKIRNQQQRQSHENIEKLSEIPESVKQRDVEVNTTAMKSEPEATLATKDTSVPFTP
KNSDGTEPPLHVLIPPRLAMPEQAHTSPTSRKSSDNQRREMEYALSPTPQGNDYQQFR
VPSTTGDPSEKAKFGNIFRKLSQRRKKTIEQTSVNSNNSINKPVQKTHSRAVSDFVPG
FAKPSYDSNYTMNEPVKTNDSRGGNKGDFPALPADAENMVEKQREKQIEEDIMKLHDI
NKQNNEVAKGSGREAYAAQKFEGSDDDENHPLPPLNVAKGRKLHPSARAKSVGHARRE
SLKYMRPPMPSSAYPQQELIDTGFLESSDDNKSDSLGNVTSQTNDSVSVHSVNAHINS
PSVEKELTDEEILQEASRAPAGSMPSIDFPRSLFLKGFFSVQTTSSKPLPIVRYKIMF
VLRKMNIEFKEVKGGFVCMQRFSSNNVAAKREGTPRSIMPLSHHESIRRQGSNKYSPS
SPLTTNSIHQRKTSITETYGDDKHSGTSLENIHQQGDGSEGMTTTEKEPIKFEIHIVK
VRIVGLAGVHFKKISGNTWLYKELASSILKELKL"
gene complement(698554..699468)
/gene="INO2"
/locus_tag="YDR123C"
/gene_synonym="DIE1; SCS1"
/db_xref="GeneID:851701"
mRNA complement(698554..699468)
/gene="INO2"
/locus_tag="YDR123C"
/gene_synonym="DIE1; SCS1"
/product="Ino2p"
/transcript_id="NM_001180431.1"
/db_xref="GI:296143477"
/db_xref="GeneID:851701"
CDS complement(698554..699468)
/gene="INO2"
/locus_tag="YDR123C"
/gene_synonym="DIE1; SCS1"
/note="Component of the heteromeric Ino2p/Ino4p basic
helix-loop-helix transcription activator that binds
inositol/choline-responsive elements (ICREs), required for
derepression of phospholipid biosynthetic genes in
response to inositol depletion"
/codon_start=1
/product="Ino2p"
/protein_id="NP_010408.1"
/db_xref="GI:6320328"
/db_xref="SGD:S000002530"
/db_xref="GeneID:851701"
/translation="MQQATGNELLGILDLDNDIDFETAYQMLSSNFDDQMSAHIHENT
FSATSPPLLTHELGIIPNVATVQPSHVETIPADNQTHHAPLHTHAHYLNHNPHQPSMG
FDQALGLKLSPSSSGLLSTNESNAIEQFLDNLISQDMMSSNASMNSESHLHIRSPKKQ
HRYTELNQRYPETHPHSNTGELPTNTADVPTEFTTREGPHQPIGNDHYNPPPFSVPEI
RIPDSDIPANIEDDPVKVRKWKHVQMEKIRRINTKEAFERLIKSVRTPPKENGKRIPK
HILLTCVMNDIKSIRSANEALQHILDDS"
gene 700315..701289
/locus_tag="YDR124W"
/db_xref="GeneID:851702"
mRNA 700315..701289
/locus_tag="YDR124W"
/product="hypothetical protein"
/transcript_id="NM_001180432.3"
/db_xref="GI:398365734"
/db_xref="GeneID:851702"
CDS 700315..701289
/locus_tag="YDR124W"
/note="hypothetical protein; non-essential gene;
expression is strongly induced by alpha factor"
/codon_start=1
/product="hypothetical protein"
/protein_id="NP_010409.3"
/db_xref="GI:398365735"
/db_xref="SGD:S000002531"
/db_xref="GeneID:851702"
/translation="MRIGMEELRRALALLNGQGYEFMVFIKEKDHLISESIPKNLFSE
SFISSSIEKNPPLTFDPLVNRKRITVYEENIQPAIMLPLDQPLLIQNYLYTAFKLLRQ
VPCKAIAKLWIKIIEPRKKTRFPYIKGNAGRPEWWPKDVEHKEPDHLQKADRLKLMCT
IIMNVLPQSPFSLEILDELTGVTAAMTIFKKETVKKVIMKNVFEIAKCLCNKDFKQKT
ISLDDLNDLAQKQKKSYHSRRFDVNKMVKVEKDLLQQSSGSDSSPSMILPSKESDTEY
FPREYPKDPVSEDYSNSISRLENLVEFDPLFLTKLDELTSSDDCKDFI"
gene complement(701397..702758)
/gene="ECM18"
/locus_tag="YDR125C"
/db_xref="GeneID:851703"
mRNA complement(701397..702758)
/gene="ECM18"
/locus_tag="YDR125C"
/product="alpha/beta hydrolase family protein"
/transcript_id="NM_001180433.3"
/db_xref="GI:398365742"
/db_xref="GeneID:851703"
CDS complement(701397..702758)
/gene="ECM18"
/locus_tag="YDR125C"
/note="hypothetical protein; ECM18 has a paralog, ICT1,
that arose from the whole genome duplication"
/codon_start=1
/product="alpha/beta hydrolase family protein"
/protein_id="NP_010410.3"
/db_xref="GI:398365743"
/db_xref="SGD:S000002532"
/db_xref="GeneID:851703"
/translation="MLLIKRYLMDPESLRRQIMNVYKCYMWKRAFHSNRSLLEVKRRE
KSLQRKILERILRPKEENAVKKSGFKLWSSHLNNPHKTYMRLEELQRRIMEEVHVEGI
KKNDKLFNEINQWHFQNENTSTVRTPTLLIHGYAASSMSFFRNYPGLSKHIRNLYSID
MPASGLSSVPSLEINTTTPLPLDIKFIGENKFKVPYTINANHNKFVIQMYEDFYLDRI
EQWRIDNKLGKMNVVGHSFGGYLSFKYAVKYPNSVNKLCLVSPLGVERNIWSVNNNFH
SNTLYTIDFKNPNSKFYSKRNMIPKYLFEQQFHILRMMGPLGAKLCWNYIMAAYSRVP
SLAYKEYIFELFYGKGGIPEVTTDIFKALFSRCILAKDPLMDSLQYLNVKKLLIVYGQ
YDWMNKKAGMFMVKELNNLKNCLEGASYLEIPSSGHNLFLDNPESFNQSIVSFLSDET
KSP"
rep_origin 702887..703132
/note="ARS422;
Autonomously Replicating Sequence"
/db_xref="SGD:S000114834"
gene 703234..704244
/gene="SWF1"
/locus_tag="YDR126W"
/gene_synonym="PSL10"
/db_xref="GeneID:851704"
mRNA 703234..704244
/gene="SWF1"
/locus_tag="YDR126W"
/gene_synonym="PSL10"
/product="Swf1p"
/transcript_id="NM_001180434.1"
/db_xref="GI:296143480"
/db_xref="GeneID:851704"
CDS 703234..704244
/gene="SWF1"
/locus_tag="YDR126W"
/gene_synonym="PSL10"
/EC_number="2.3.1.-"
/note="Palmitoyltransferase that acts on transmembrane
proteins, including the SNAREs Snc1p, Syn8p, Tlg1p and
likely all SNAREs; contains an Asp-His-His-Cys-cysteine
rich (DHHC-CRD) domain; may have a role in vacuole fusion"
/codon_start=1
/product="Swf1p"
/protein_id="NP_010411.1"
/db_xref="GI:6320331"
/db_xref="SGD:S000002533"
/db_xref="GeneID:851704"
/translation="MSWNLLFVLLIGFVVLILLSPVFKSTWPFSTFYRNVFQPFLVDD
QKYRWKLHLVPLFYTSIYLYLVYTYHMRVESTIKNELFLLERILIVPIIILPPVALGI
LAMVSRAEDSKDHKSGSTEEYPYDYLLYYPAIKCSTCRIVKPARSKHCSICNRCVLVA
DHHCIWINNCIGKGNYLQFYLFLISNIFSMCYAFLRLWYISLNSTSTLPRAVLTLTIL
CGCFTIICAIFTYLQLAIVKEGMTTNEQDKWYTIQEYMREGKLVRSLDDDCPSWFFKC
TEQKDDAAEPLQDQHVTFYSTNAYDHKHYNLTHYITIKDASEIPNIYDKGTFLANLTD
LI"
gene 704484..709250
/gene="ARO1"
/locus_tag="YDR127W"
/db_xref="GeneID:851705"
mRNA 704484..709250
/gene="ARO1"
/locus_tag="YDR127W"
/product="pentafunctional protein ARO1p"
/transcript_id="NM_001180435.1"
/db_xref="GI:296143481"
/db_xref="GeneID:851705"
CDS 704484..709250
/gene="ARO1"
/locus_tag="YDR127W"
/EC_number="2.7.1.71"
/EC_number="1.1.1.25"
/EC_number="2.5.1.19"
/EC_number="4.2.3.4"
/EC_number="4.2.1.10"
/note="Pentafunctional arom protein, catalyzes steps 2
through 6 in the biosynthesis of chorismate, which is a
precursor to aromatic amino acids"
/codon_start=1
/product="pentafunctional protein ARO1p"
/protein_id="NP_010412.1"
/db_xref="GI:6320332"
/db_xref="SGD:S000002534"
/db_xref="GeneID:851705"
/translation="MVQLAKVPILGNDIIHVGYNIHDHLVETIIKHCPSSTYVICNDT
NLSKVPYYQQLVLEFKASLPEGSRLLTYVVKPGETSKSRETKAQLEDYLLVEGCTRDT
VMVAIGGGVIGDMIGFVASTFMRGVRVVQVPTSLLAMVDSSIGGKTAIDTPLGKNFIG
AFWQPKFVLVDIKWLETLAKREFINGMAEVIKTACIWNADEFTRLESNASLFLNVVNG
AKNVKVTNQLTNEIDEISNTDIEAMLDHTYKLVLESIKVKAEVVSSDERESSLRNLLN
FGHSIGHAYEAILTPQALHGECVSIGMVKEAELSRYFGILSPTQVARLSKILVAYGLP
VSPDEKWFKELTLHKKTPLDILLKKMSIDKKNEGSKKKVVILESIGKCYGDSAQFVSD
EDLRFILTDETLVYPFKDIPADQQKVVIPPGSKSISNRALILAALGEGQCKIKNLLHS
DDTKHMLTAVHELKGATISWEDNGETVVVEGHGGSTLSACADPLYLGNAGTASRFLTS
LAALVNSTSSQKYIVLTGNARMQQRPIAPLVDSLRANGTKIEYLNNEGSLPIKVYTDS
VFKGGRIELAATVSSQYVSSILMCAPYAEEPVTLALVGGKPISKLYVDMTIKMMEKFG
INVETSTTEPYTYYIPKGHYINPSEYVIESDASSATYPLAFAAMTGTTVTVPNIGFES
LQGDARFARDVLKPMGCKITQTATSTTVSGPPVGTLKPLKHVDMEPMTDAFLTACVVA
AISHDSDPNSANTTTIEGIANQRVKECNRILAMATELAKFGVKTTELPDGIQVHGLNS
IKDLKVPSDSSGPVGVCTYDDHRVAMSFSLLAGMVNSQNERDEVANPVRILERHCTGK
TWPGWWDVLHSELGAKLDGAEPLECTSKKNSKKSVVIIGMRAAGKTTISKWCASALGY
KLVDLDELFEQQHNNQSVKQFVVENGWEKFREEETRIFKEVIQNYGDDGYVFSTGGGI
VESAESRKALKDFASSGGYVLHLHRDIEETIVFLQSDPSRPAYVEEIREVWNRREGWY
KECSNFSFFAPHCSAEAEFQALRRSFSKYIATITGVREIEIPSGRSAFVCLTFDDLTE
QTENLTPICYGCEAVEVRVDHLANYSADFVSKQLSILRKATDSIPIIFTVRTMKQGGN
FPDEEFKTLRELYDIALKNGVEFLDLELTLPTDIQYEVINKRGNTKIIGSHHDFQGLY
SWDDAEWENRFNQALTLDVDVVKFVGTAVNFEDNLRLEHFRDTHKNKPLIAVNMTSKG
SISRVLNNVLTPVTSDLLPNSAAPGQLTVAQINKMYTSMGGIEPKELFVVGKPIGHSR
SPILHNTGYEILGLPHKFDKFETESAQLVKEKLLDGNKNFGGAAVTIPLKLDIMQYMD
ELTDAAKVIGAVNTVIPLGNKKFKGDNTDWLGIRNALINNGVPEYVGHTAGLVIGAGG
TSRAALYALHSLGCKKIFIINRTTSKLKPLIESLPSEFNIIGIESTKSIEEIKEHVGV
AVSCVPADKPLDDELLSKLERFLVKGAHAAFVPTLLEAAYKPSVTPVMTISQDKYQWH
VVPGSQMLVHQGVAQFEKWTGFKGPFKAIFDAVTKE"
gene 709549..712995
/gene="MTC5"
/locus_tag="YDR128W"
/gene_synonym="SEA3"
/db_xref="GeneID:851706"
mRNA 709549..712995
/gene="MTC5"
/locus_tag="YDR128W"
/gene_synonym="SEA3"
/product="Mtc5p"
/transcript_id="NM_001180436.3"
/db_xref="GI:398365748"
/db_xref="GeneID:851706"
CDS 709549..712995
/gene="MTC5"
/locus_tag="YDR128W"
/gene_synonym="SEA3"
/note="Subunit of the SEA (Seh1-associated) complex; SEA
is a coatomer-related complex that associates dynamically
with the vacuole; has N-terminal WD-40 repeats and a
C-terminal RING motif; mtc5 is synthetically sick with
cdc13-1; relative distribution to vacuolar membrane
punctae decreases upon DNA replication stress"
/codon_start=1
/product="Mtc5p"
/protein_id="NP_010413.3"
/db_xref="GI:398365749"
/db_xref="SGD:S000002535"
/db_xref="GeneID:851706"
/translation="MCSSINEGPYNSPTFGKSLSLKVDGGFNAVSINPSGRDIVLASR
QGLYIIDLDDPFTPPRWLHHITPWQVADVQWSPHPAKPYWIVSTSNQKAIIWNLAKSS
SNAIEFVLHGHSRAITDINFNPQHPDVLATCSVDTYVHAWDMRSPHRPFYSTSSWRSA
ASQVKWNYKDPNVLASSHGNDIFVWDLRKGSTPLCSLKGHVSSVNSIDFNRFKYSEIM
SSSNDGTVKFWDYSKSTTESKRTVTTNFPIWRGRYLPFGEGYCIMPMVGGNNAVYLIN
LCDDDDSEQNKKTKLQPIYAFKGHSDRVIDFLWRSRHTCDGDYDDREFQLVTWSKDCD
LKLWPISDSIYGKVNFDRGKRLEEKLPDYDYCSYNKEPENRENVQKNEFRRLRENFVT
TSGLKKNKTNHITWLSGIRMNSATSQEDLFNETKIQNLGEEVSAIGHKFPKVVFEKIS
VSTRELCLTLNGPWSEENPDDYIFLRISINFPLNYPNKGDPPKFTIEENSNLTMSKRQ
EILSNLATIGQKYTDSNLYCLEPCIRFVLGEKVSLEDIEEGQEPLLNFDIADHIDFEE
LSSLDSSYSDSQNPENLSSQSDIESYKEALVFPDTSNQGLDFGRNLALDTTPVPNGCG
SCWTATGELFCFFANEKKPEKKQNAIIKLSQKEAGVEKHPFKIEPQVLYDKEVDSSVI
TAADELKARPKRYVDTLGLGGGTNGDSRTYFDDETSSDDSFDSVADDWDDILRNDIIV
RTKIPILRGNFKAFSSVHSESGKTVESTKKNKNLVISKNFSSLLSDRKELALEYLFMD
ATPEGFARNNALVAEKFDLDEISHCWQILSDMLIDQSDYDPYTTIWNNHPMGIKWFIK
EAIVYFERQQNLQMLAMLCCVILSARRKKIPARYYGQELENMEGTIVFNDNESQNTSF
WKGSDAFSTRSRSSTVTPNFYGNHLRGKNIHGGDNSSIRSDDHHARLRTHNTLNGSSK
FTEPAQKQGSRAISSSPFHSRMPDIKVELLHDDIIEAYEQEDLLHLEVSDIPKFQTYI
YQYSKLLFRWGLPLERVKILKVSTDFRSSYSSQGIPPNNNKKSPYNGVLTHWIENNEF
GEEKFLARNCNYCDLRVTRSSFICGNCQHVLHSSCARIWWEIGDECPSGCGCNCPEMF
DA"
gene complement(713340..715379)
/gene="SAC6"
/locus_tag="YDR129C"
/gene_synonym="ABP67"
/db_xref="GeneID:851707"
mRNA complement(join(713340..715247,715359..715379))
/gene="SAC6"
/locus_tag="YDR129C"
/gene_synonym="ABP67"
/product="Sac6p"
/transcript_id="NM_001180437.3"
/db_xref="GI:398365758"
/db_xref="GeneID:851707"
CDS complement(join(713340..715247,715359..715379))
/gene="SAC6"
/locus_tag="YDR129C"
/gene_synonym="ABP67"
/note="Fimbrin, actin-bundling protein; cooperates with
Scp1p (calponin/transgelin) in the organization and
maintenance of the actin cytoskeleton; relocalizes from
plasma membrane to cytoplasm upon DNA replication stress"
/codon_start=1
/product="Sac6p"
/protein_id="NP_010414.3"
/db_xref="GI:398365759"
/db_xref="SGD:S000002536"
/db_xref="GeneID:851707"
/translation="MNIVKLQRKFPILTQEDLFSTIEKFRAIDLDDKGWVEKQQALEA
VSKDGDATYDEARETLKHVGVDASGRVELDDYVGLVAKLRESKTGAAPQTTFNVAPNS
TPIVSTAATGLQHKGKGTQAKIIVAGSQTGTTHTINEEERREFTKHINSVLAGDQDIG
DLLPFPTDTFQLFDECRDGLVLSKLINDSVPDTIDTRVLNWPKKGKELNNFQASENAN
IVINSAKAIGCVVVNVHSEDIIEGREHLILGLIWQIIRRGLLSKIDIKLHPELYRLLE
DDETLEQFLRLPPEQILLRWFNYHLKQANWNRRVTNFSKDVSDGENYTILLNQLDPAL
CSKAPLQTTDLMERAEQVLQNAEKLDCRKYLTPSSLVAGNPKLNLAFVAHLFNTHPGL
EPIQEEEKPEIEEFDAEGEREARVFTLWLNSLDVDPPVISLFDDLKDGLILLQAYEKV
MPGAVDFKHVNKRPASGAEISRFKALENTNYAVDLGRAKGFSLVGIEGSDIVDGNKLL
TLGLVWQLMRRNISITMKTLSSSGRDMSDSQILKWAQDQVTKGGKNSTIRSFKDQALS
NAHFLLDVLNGIAPGYVDYDLVTPGNTEEERYANARLAISIARKLGALIWLVPEDINE
VRARLIITFIASLMTLNK"
gene complement(715747..716622)
/gene="FIN1"
/locus_tag="YDR130C"
/db_xref="GeneID:851708"
mRNA complement(715747..716622)
/gene="FIN1"
/locus_tag="YDR130C"
/product="Fin1p"
/transcript_id="NM_001180438.1"
/db_xref="GI:296143484"
/db_xref="GeneID:851708"
CDS complement(715747..716622)
/gene="FIN1"
/locus_tag="YDR130C"
/note="Spindle pole body-related intermediate filament
protein; forms cell cycle-specific filaments between
spindle pole bodies in dividing cells; localizes to poles
and microtubules of spindle during anaphase and
contributes to spindle stability; involved in Glc7p
localization and regulation; relative distribution to the
nucleus increases upon DNA replication stress"
/codon_start=1
/product="Fin1p"
/protein_id="NP_010415.1"
/db_xref="GI:6320335"
/db_xref="SGD:S000002537"
/db_xref="GeneID:851708"
/translation="MSNKSNRRSLRDIGNTIGRNNIPSDKDNVFVRLSMSPLRTTSQK
EFLKPPMRISPNKTDGMKHSIQVTPRRIMSPECLKGYVSKETQSLDRPQFKNSNKNVK
IQNSDHITNIIFPTSPTKLTFSNENKIGGDGSLTRIRARFKNGLMSPERIQQQQQQHI
LPSDAKSNTDLCSNTELKDAPFENDLPRAKLKGKNLLVELKKEEEDVGNGIESLTKSN
TKLNSMLANEGKIHKASFQKSVKFKLPDNIVTEETVELKEIKDLLLQMLRRQREIESR
LSNIELQLTEIPKHK"
gene complement(716790..718460)
/locus_tag="YDR131C"
/db_xref="GeneID:851709"
mRNA complement(716790..718460)
/locus_tag="YDR131C"
/product="hypothetical protein"
/transcript_id="NM_001180439.1"
/db_xref="GI:296143485"
/db_xref="GeneID:851709"
CDS complement(716790..718460)
/locus_tag="YDR131C"
/note="F-box protein, substrate-specific adaptor subunit
that recruits substrates to a core ubiquitination complex"
/codon_start=1
/product="hypothetical protein"
/protein_id="NP_010416.1"
/db_xref="GI:6320336"
/db_xref="SGD:S000002538"
/db_xref="GeneID:851709"
/translation="MFDKLPYEIFKQIAWRIPQEDKISLTYVCKRSYESIIPFIYQNL
FLNETYHINGDYDNSFGTCYWSVLNFHYIDEDDSNTKNDMSNRRLAKVKFSYFERTLA
ESPKRLCPLINRIRCTWHLNEDVMTNVLKLLSEYGSNLKFVDQFVRSSVNKGLEPLSK
QLKTLTLTPPTLMPTHNSVSGSYLNKIDRLLLKCDLSRLEKLSIHINALKYFKNTGSP
MKIKALVLNLRPDTLNLAEYDASDDFLKELEYIDIFDASTLRQLEILSWYSRDDFPSG
EEGGFDRLYVKWGLEGFWKFPNIEKLSLASLVYSEFFLMNCLAVFHNLKILKLDYMGK
FDFDVSLINFLSKQVCGKKLQRFDIHCQLNHRLFFPMTDNPLTRLNFDGFCPCSTCKN
TIHEVILKKIFPETRSKLLKNPNKFQAHNFFYQMFFENKIMPYTNIIDNESPAMGWDS
VPIETFVRKFNENLQSTIENTENITVNKITREDAISLYHLYLHYLKDVFKVFEQSLPN
LEYLTINGIPTKIIQVDELQRCAVPLFYNNGYKSNSVYELVDAEALFS"
gene complement(718816..720303)
/locus_tag="YDR132C"
/db_xref="GeneID:851710"
mRNA complement(718816..720303)
/locus_tag="YDR132C"
/product="hypothetical protein"
/transcript_id="NM_001180440.3"
/db_xref="GI:398365764"
/db_xref="GeneID:851710"
CDS complement(718816..720303)
/locus_tag="YDR132C"
/note="hypothetical protein; protein increases in
abundance and relative distribution to the nucleus
increases upon DNA replication stress"
/codon_start=1
/product="hypothetical protein"
/protein_id="NP_010417.3"
/db_xref="GI:398365765"
/db_xref="SGD:S000002539"
/db_xref="GeneID:851710"
/translation="MSNSPTVATLSQEYFDPNIPQILPHEKMYKIQVGKSLFKISGAS
LSSDGPSFFTEYFSKKRSPSNNDDSNNDTMESNKNEVLFIDRSAEVFEWIYQHLQGYI
IEIKDEVQYTMLFADAMYYNLPRLRSLLKETDYYFTNIGGQSFKIAKNLFRREGDSPN
YFEIYAATVYIDVEELIISKKLLRPPSHSAPYIPRSSEYFKDLLTLLGGASIDLDDNK
RNALIKECRYYRLLNLEQRLIKSHISYNPITRKEEICLLLKDLSKKGITFPASSAFST
SPYFEDDFCSINECDSLSKTREQPANKKIKLDMTEKYNDSWNMLCYKRPFLDKHPREL
IFQINSTDCTIILNKESQSIHVDITGESAYKFEALFGSHLPNTPSGAPKLKNYQYRFP
SDSTQTKIETHYLLPACIYLCDLDINGIKISQVQTLLTDKNKFNDRVIDVSDPLDLRF
CSGLKLYLRKSLWKLAVKDGNIMLIAIKAIAFNGTKEYYKGYEYL"
gene complement(721071..721481)
/locus_tag="YDR134C"
/note="hypothetical protein; YDR134C has a paralog, CCW12,
that arose from the whole genome duplication"
/pseudo
/db_xref="GeneID:851712"
/db_xref="SGD:S000002541"
mRNA complement(721071..721481)
/locus_tag="YDR134C"
/pseudo
/db_xref="GeneID:851712"
/db_xref="SGD:S000002541"
gene complement(723004..727551)
/gene="YCF1"
/locus_tag="YDR135C"
/db_xref="GeneID:851713"
mRNA complement(723004..727551)
/gene="YCF1"
/locus_tag="YDR135C"
/product="ATP-binding cassette glutathione S-conjugate
transporter YCF1"
/transcript_id="NM_001180442.3"
/db_xref="GI:398365778"
/db_xref="GeneID:851713"
CDS complement(723004..727551)
/gene="YCF1"
/locus_tag="YDR135C"
/note="Vacuolar glutathione S-conjugate transporter;
member of the ATP-binding cassette family; has a role in
detoxifying metals such as cadmium, mercury, and arsenite;
also transports unconjugated bilirubin,
selenodigluthatione, and oxidized glutathione; similar to
human cystic fibrosis protein CFTR"
/codon_start=1
/product="ATP-binding cassette glutathione S-conjugate
transporter YCF1"
/protein_id="NP_010419.3"
/db_xref="GI:398365779"
/db_xref="SGD:S000002542"
/db_xref="GeneID:851713"
/translation="MAGNLVSWACKLCRSPEGFGPISFYGDFTQCFIDGVILNLSAIF
MITFGIRDLVNLCKKKHSGIKYRRNWIIVSRMALVLLEIAFVSLASLNISKEEAENFT
IVSQYASTMLSLFVALALHWIEYDRSVVANTVLLFYWLFETFGNFAKLINILIRHTYE
GIWYSGQTGFILTLFQVITCASILLLEALPKKPLMPHQHIHQTLTRRKPNPYDSANIF
SRITFSWMSGLMKTGYEKYLVEADLYKLPRNFSSEELSQKLEKNWENELKQKSNPSLS
WAICRTFGSKMLLAAFFKAIHDVLAFTQPQLLRILIKFVTDYNSERQDDHSSLQGFEN
NHPQKLPIVRGFLIAFAMFLVGFTQTSVLHQYFLNVFNTGMYIKSALTALIYQKSLVL
SNEASGLSSTGDIVNLMSVDVQKLQDLTQWLNLIWSGPFQIIICLYSLYKLLGNSMWV
GVIILVIMMPLNSFLMRIQKKLQKSQMKYKDERTRVISEILNNIKSLKLYAWEKPYRE
KLEEVRNNKELKNLTKLGCYMAVTSFQFNIVPFLVSCCTFAVFVYTEDRALTTDLVFP
ALTLFNLLSFPLMIIPMVLNSFIEASVSIGRLFTFFTNEELQPDSVQRLPKVKNIGDV
AINIGDDATFLWQRKPEYKVALKNINFQAKKGNLTCIVGKVGSGKTALLSCMLGDLFR
VKGFATVHGSVAYVSQVPWIMNGTVKENILFGHRYDAEFYEKTIKACALTIDLAILMD
GDKTLVGEKGISLSGGQKARLSLARAVYARADTYLLDDPLAAVDEHVARHLIEHVLGP
NGLLHTKTKVLATNKVSALSIADSIALLDNGEITQQGTYDEITKDADSPLWKLLNNYG
KKNNGKSNEFGDSSESSVRESSIPVEGELEQLQKLNDLDFGNSDAISLRRASDATLGS
IDFGDDENIAKREHREQGKVKWNIYLEYAKACNPKSVCVFILFIVISMFLSVMGNVWL
KHWSEVNSRYGSNPNAARYLAIYFALGIGSALATLIQTIVLWVFCTIHASKYLHNLMT
NSVLRAPMTFFETTPIGRILNRFSNDIYKVDALLGRTFSQFFVNAVKVTFTITVICAT
TWQFIFIIIPLSVFYIYYQQYYLRTSRELRRLDSITRSPIYSHFQETLGGLATVRGYS
QQKRFSHINQCRIDNNMSAFYPSINANRWLAYRLELIGSIIILGAATLSVFRLKQGTL
TAGMVGLSLSYALQITQTLNWIVRMTVEVETNIVSVERIKEYADLKSEAPLIVEGHRP
PKEWPSQGDIKFNNYSTRYRPELDLVLKHINIHIKPNEKVGIVGRTGAGKSSLTLALF
RMIEASEGNIVIDNIAINEIGLYDLRHKLSIIPQDSQVFEGTVRENIDPINQYTDEAI
WRALELSHLKEHVLSMSNDGLDAQLTEGGGNLSVGQRQLLCLARAMLVPSKILVLDEA
TAAVDVETDKVVQETIRTAFKDRTILTIAHRLNTIMDSDRIIVLDNGKVAEFDSPGQL
LSDNKSLFYSLCMEAGLVNEN"
gene 728259..730250
/gene="RGP1"
/locus_tag="YDR137W"
/db_xref="GeneID:851714"
mRNA 728259..730250
/gene="RGP1"
/locus_tag="YDR137W"
/product="Rgp1p"
/transcript_id="NM_001180444.1"
/db_xref="GI:296143488"
/db_xref="GeneID:851714"
CDS 728259..730250
/gene="RGP1"
/locus_tag="YDR137W"
/note="Subunit of a Golgi membrane exchange factor
(Ric1p-Rgp1p) that catalyzes nucleotide exchange on Ypt6p"
/codon_start=1
/product="Rgp1p"
/protein_id="NP_010421.1"
/db_xref="GI:6320340"
/db_xref="SGD:S000002544"
/db_xref="GeneID:851714"
/translation="MRAHRIDTFLIRENIKLEIIHESNSYFGGEHISIAFRFKHLGSQ
HELFNYKEKLLTVDKAVEEKLEQQAKVQDDGEGTMENQTWSLKSLLGAFKRTGEPEES
VDVDNMKMLNESKMLREKIQKQMYFHQPVTLISGYVQISGVFQYDSEVISESKFKQDE
VKMVGLDIVPGHTTNSVLALEDGEHFKGKRNLTNYLNSDYTNVTNGLLFSESGSRGRT
GTYNERTLMISNDTSIKTLPLLLIPQTLLFSEISLEPGEVRTFYFKSTKLPKDICPSY
SSSKVASINYTLEVGADVLSDDNIEKFSNRVPITIAPYISSNAEQYTSRLDKPAIILK
TGNIKELKPRLFTRKVSTASAVSFGRRKSSIIDIDSPLEDNEFVKRVKKNFIELVESN
QNVSRDIDELIDLQMGVQFGKDEDSSDPEPNDSHFSNEMVTSAESSLRSDAVTKRRKS
YSVRDNISNLEQKMWNDCSLVKSDENSNLLPQLINLQNAYQINRNNETMAKVSLSAPF
YKTTDDINLVIELDPITTPLLKVTSLTVSLESFEIINPKYKTEGKGIGSKPKGNSVYE
KHFICFDECKSVSVKLLPPRSPTNQITGQFKTDVFQHKWMIGLKFVIIAKTESITLDQ
FYEDKKGILFHSKENLEGEEFTCYVPIPILCTSEDFMGW"
gene 730578..732836
/gene="HPR1"
/locus_tag="YDR138W"
/gene_synonym="TRF1"
/db_xref="GeneID:851716"
mRNA 730578..732836
/gene="HPR1"
/locus_tag="YDR138W"
/gene_synonym="TRF1"
/product="Hpr1p"
/transcript_id="NM_001180445.1"
/db_xref="GI:296143489"
/db_xref="GeneID:851716"
CDS 730578..732836
/gene="HPR1"
/locus_tag="YDR138W"
/gene_synonym="TRF1"
/note="Subunit of THO/TREX complexes that couple
transcription elongation with mitotic recombination and
with mRNA metabolism and export, subunit of an RNA Pol II
complex; regulates lifespan; involved in telomere
maintenance; similar to Top1p"
/codon_start=1
/product="Hpr1p"
/protein_id="NP_010422.1"
/db_xref="GI:6320342"
/db_xref="SGD:S000002545"
/db_xref="GeneID:851716"
/translation="MSNTEELIQNSIGFLQKTFKALPVSFDSIRHEPLPSSMLHASVL
NFEWEPLEKNISAIHDRDSLIDIILKRFIIDSMTNAIEDEEENNLEKGLLNSCIGLDF
VYNSRFNRSNPASWGNTFFELFSTIIDLLNSPSTFLKFWPYAESRIEWFKMNTSVEPV
SLGESNLISYKQPLYEKLRHWNDILAKLENNDILNTVKHYNMKYKLENFLSELLPINE
ESNFNRSASISALQESDNEWNRSARERESNRSSDVIFAADYNFVFYHLIICPIEFAFS
DLEYKNDVDRSLSPLLDAILEIEENFYSKIKMNNRTRYSLEEALNTEYYANYDVMTPK
LPVYMKHSNAMKMDRNEFWANLQNIKESDDYTLRPTIMDISLSNTTCLYKQLTQEDDD
YYRKQFILQLCFTTNLIRNLISSDETRNFYKSCYLRENPLSDIDFENLDEVNKKRGLN
LCSYICDNRVLKFYKIKDPDFYRVIRKLMSSDEKFTTAKIDGFKEFQNFRISKEKIPP
PAFDETFKKFTFIKMGNKLINNVWKIPTGLDKIEQEVKKPEGVYEAAQAKWESKISSE
TSGGEAKDEIIRQWQTLRFLRSRYLFDFDKVNEKTGVDGLFEEPRKVEALDDSFKEKL
LYKINQEHRKKLQDAREYKIGKERKKRALEEEASFPEREQKIKSQRINSASQTEGDEL
KSEQTQPKGEISEENTKIKSSEVSSQDPDSGVAGEFAPQNTTAQLENPKTEDNNAATS
NISNGSSTQDMK"
gene complement(733618..733924)
/gene="RUB1"
/locus_tag="YDR139C"
/db_xref="GeneID:851717"
mRNA complement(join(733618..733702,733776..733924))
/gene="RUB1"
/locus_tag="YDR139C"
/product="NEDD8 family protein RUB1"
/transcript_id="NM_001180446.3"
/db_xref="GI:398365788"
/db_xref="GeneID:851717"
CDS complement(join(733618..733702,733776..733924))
/gene="RUB1"
/locus_tag="YDR139C"
/note="Ubiquitin-like protein with similarity to mammalian
NEDD8; conjugation (neddylation) substrates include the
cullins Cdc53p, Rtt101p, and Cul3p; activated by Ula1p and
Uba3p (E1 enzyme pair); conjugation mediated by Ubc12p (E2
enzyme)"
/codon_start=1
/product="NEDD8 family protein RUB1"
/protein_id="NP_010423.4"
/db_xref="GI:398365789"
/db_xref="SGD:S000002546"
/db_xref="GeneID:851717"
/translation="MIVKVKTLTGKEISVELKESDLVYHIKELLEEKEGIPPSQQRLI
FQGKQIDDKLTVTDAHLVEGMQLHLVLTLRGGN"
gene 734138..734803
/gene="MTQ2"
/locus_tag="YDR140W"
/db_xref="GeneID:851718"
mRNA 734138..734803
/gene="MTQ2"
/locus_tag="YDR140W"
/product="Mtq2p"
/transcript_id="NM_001180447.3"
/db_xref="GI:398365790"
/db_xref="GeneID:851718"
CDS 734138..734803
/gene="MTQ2"
/locus_tag="YDR140W"
/EC_number="2.1.1.-"
/note="S-adenosylmethionine-dependent methyltransferase of
the seven beta-strand family; subunit of complex with
Trm112p that methylates translation release factor Sup45p
(eRF1) in the ternary complex eRF1-eRF3-GTP; similar to
E.coli PrmC"
/codon_start=1
/product="Mtq2p"
/protein_id="NP_010424.3"
/db_xref="GI:398365791"
/db_xref="SGD:S000002547"
/db_xref="GeneID:851718"
/translation="MLPTPYVKCDYDKVYEPAEDSFLILDCLEKEHDFLKQKFGNRLA
IVCEIGSGSGIVTTFLMQNKIIPQENSIHLAVDINPWALEATLDTAKLNSCKSSFLEV
IQADLNSSIRNNQVDVLIFNPPYVPAECVPDVPGSREEADQWLDLALLGGKDGMAITD
KLLRQLEQILSPDGVAYILFCARNKPKEVIKRFVDTYKWNVKLIETRKAGWEVLSVYS
FTR"
gene complement(734901..739997)
/gene="DOP1"
/locus_tag="YDR141C"
/db_xref="GeneID:851719"
mRNA complement(734901..739997)
/gene="DOP1"
/locus_tag="YDR141C"
/product="Dop1p"
/transcript_id="NM_001180448.1"
/db_xref="GI:296143492"
/db_xref="GeneID:851719"
CDS complement(734901..739997)
/gene="DOP1"
/locus_tag="YDR141C"
/note="Golgi-localized, leucine-zipper domain containing
protein; involved in endosome to Golgi transport,
organization of the ER, establishing cell polarity, and
morphogenesis; detected in highly purified mitochondria in
high-throughput studies"
/codon_start=1
/product="Dop1p"
/protein_id="NP_010425.1"
/db_xref="GI:6320345"
/db_xref="SGD:S000002548"
/db_xref="GeneID:851719"
/translation="MSLPLKPLTIDSNNKQLDSKQKKFRANVERALERFDSVTEWADY
IASLGTLLKALQSWSPKFQNVRYYVPSPYQVSRRLTSSLSPALPAGVHQKTLEVYTYI
FEHIGLETLATECNIWIPGILPLMTYASMSVRSHLIELYDNYILLLPQTTLRLLIRPL
ISSLLPGIDDESNDFLPLTLKLIETLQENLDDDSLFWQTLFLVMTANKGRRLGGLTWL
TRKFPSLNAVPHLVNKIKMEAEENPSETETNDSHLDRKKRKEEAFKVLLPAAKDLVTP
EPGLLIRCLVGCLEDENDILIKRSVLDLLLQRLRLDSPVLNVLITSEDKKLLIMSCCR
TTLSKDMSLNRRIWNWLLGPTAGGMLNNNGGNSMEYTTSVKSANEESNVYFTKYGLSA
LLEGLSDLLSEEESVLTAFRISMAVMDRWEIGSLVIPELFIPLLYSSEKFKQNEQIMK
TARTFFDNTETNIIWGKLFQELEDIKNLKILDFVLTNFNIGNDEEIIVRHLPLILLTL
LALPSNDKDFDNIYKLQKFSLYNKLLNYIPERALLPLSHSKLKHDDEVSCEELLAKIR
GFYTNVSNPSSILEKENIAERLPPFTTEDLTFLIADLIQKKLLSSLWDLENINESSKL
FIAIFEKIPESEELKGRSHISWSDKKITQSIFEAIPRLCESNNDAKSEEIVGIVEIFG
NYLYSRMEFIESMKLLKVVMMAVWKSLKDPRHQILGVKNLKTLNRFIPSKFIESALVY
TFVEEEDISERLSVLDLLWTQLDSDSNLIRRPLELILGELFDDQNPFYLTVSKWILSI
LNSGSASRLFYILTDNILKVNRLEKERLDERDDLDMLTYEFQMLAYVLKTNNGRTRKV
FSTELTSIKSSTIWKNEDVSTYKSLLLVTLMRFLNIKSNTHAKSIRSALILLDILLDG
TEQNFKDIVIFLLQMSSKYIAEEGIEPELIAVSLLDIVSKVLRLSHDNGIKLDIFDDN
AAHLKYIDFLVTSVSNMKSPLIVTAYVKLLSESIVYFENSIFRMILPLSASLVQCVQR
LFLLEKREGGYYQPIALLLGGLEELLEISHGYLVTEEREGYFSGSNLKGDFIQSVVSN
VFSSDSSNEESKIQGERDVILQSFRQVISCCLDIWYWAHNISCKSNDDSSLDATNHNS
YKFKFRSKKLLETLFLLEPLELLENLISIRSDNTTVTLVHVLDGNKPAITIPHLLYGV
IIRYNRTASVKFSNRDGSRSSTTKLTKGEPSMLKRLSGESIIAFLFNYVDSVENSAME
EFYGDFLLFFREVATNYNLYSDVSLSILKLVALISGKVSKTQFGEQKRVRREISDVFF
KYLPNAFINFTNLYRGHPDSFKDLEFVVWRVQYIVNDQIGGDKFNTTLATIVNQCLTP
YIKPKSEKTIPGYVLELAAVVSHLGSKVKSWRLLIAELFQNDKKLSVIGSDQTWEKII
YEWSIYPENKSKILNDLLLEIGSKRSSVTPTLITFNLGSDSEVEYKCQNLLKISYLLM
VSPNDAYLLHFSSLISCIFHYLVSKDIKLKGSCWILLRVLLLRFSESHFNDYWSMISY
CLQTNLQEFYESLQIQSEVDPQTILQVCKTLDLLLLLNMEGFTSTNEWIFVIDTINCV
YKTNSFVALVDEIAEFKDYEITKTDDLELPTTLKDGLPLLRGIHKIERHTQLRSFFQN
LSYLHYEKVYGLGSVDLYGCGEDLKKDILS"
gene complement(740473..741600)
/gene="PEX7"
/locus_tag="YDR142C"
/gene_synonym="PAS7; PEB1"
/db_xref="GeneID:851720"
mRNA complement(740473..741600)
/gene="PEX7"
/locus_tag="YDR142C"
/gene_synonym="PAS7; PEB1"
/product="Pex7p"
/transcript_id="NM_001180449.1"
/db_xref="GI:296143493"
/db_xref="GeneID:851720"
CDS complement(740473..741600)
/gene="PEX7"
/locus_tag="YDR142C"
/gene_synonym="PAS7; PEB1"
/note="Peroxisomal signal receptor for the N-terminal
nonapeptide signal (PTS2) of peroxisomal matrix proteins;
WD repeat protein; defects in human homolog cause lethal
rhizomelic chondrodysplasia punctata (RCDP)"
/codon_start=1
/product="Pex7p"
/protein_id="NP_010426.1"
/db_xref="GI:6320346"
/db_xref="SGD:S000002549"
/db_xref="GeneID:851720"
/translation="MLRYHMQGFSGYGVQYSPFFDNRLAVAAGSNFGLVGNGKLFILE
IDRSGRIVEVNSFLTQDCLFDLAWNESHENQVLVAQGDGTLRLFDTTFKEFPIAIFKE
HEREVFSCNWNLVNRQNFLSSSWDGSIKIWSPLRKQSLMTLTPRPLEITKMVDPLNAI
ILKKKSFTGISKNRNCVYQAQFSPHDQNLVLSCSGNSYASLFDIRLPSGKNQNNFLVH
SGLEALTCDFNKYRPYVVATGGVDNAIRIWDIRMLNKNESATIKRTVPGQLHNSSCIN
EIPNAHGLAIRKVTWSPHHSNILMSASYDMTCRIWRDLSNDGAKETYKTNSTDATKGS
IFNFTQHSEFVFGADWSLWGKPGYVASTAWDGNLFVWNGLG"
gene complement(742042..743874)
/gene="SAN1"
/locus_tag="YDR143C"
/db_xref="GeneID:851721"
mRNA complement(742042..743874)
/gene="SAN1"
/locus_tag="YDR143C"
/product="ubiquitin-protein ligase SAN1"
/transcript_id="NM_001180450.3"
/db_xref="GI:398365818"
/db_xref="GeneID:851721"
CDS complement(742042..743874)
/gene="SAN1"
/locus_tag="YDR143C"
/note="Ubiquitin-protein ligase; involved in the
proteasome-dependent degradation of aberrant nuclear
proteins; targets substrates with regions of exposed
hydrophobicity containing 5 or more contiguous hydrophobic
residues; contains intrinsically disordered regions that
contribute to substrate recognition"
/codon_start=1
/product="ubiquitin-protein ligase SAN1"
/protein_id="NP_010427.3"
/db_xref="GI:398365819"
/db_xref="SGD:S000002550"
/db_xref="GeneID:851721"
/translation="MSESGQEQNRGTNTSPNNAENNNNSNAASGPLNGGAEQTRNITV
SIQYSYFTPERLAHLSNISNNDNNENNSAASGSTIANGTGPSFGIGNGGHQPDGALVL
SFRDVPASTPQDRLNSFISVAAQLAMERFNRLLNRPKGISKDEFDKLPVLQVSDLPKA
EGPLCSICYDEYEDEVDSTKAKRKRDSENEEESEGTKKRKDNEGAPLRTTADNDSNPS
ITNATVVEPPSIPLTEQQRTLNDEETNPSYKHSPIKLPCGHIFGRECIYKWSRLENSC
PLCRQKISESVGVQRAAQQDTDEVAANEAAFERIRRVLYDPTAVNSTNENSSAPSENT
SNTTVPTIGNASSGEQMLSRTGFFLVPQNGQPLHNPVRLPPNDSDRNGVNGPSSTTQN
PPSNSGGSNNNQSPRWVPIPLTLFQFHSPNPNPSASDSSASPSAANGPNSNNTSSDAT
DPHHNRLRAVLDHIFNVAQRGTSDTSATTAPGAQTVHNQGRNDSSSSDTTQGSSFLEN
ISRLTGHFTNGSRDNNNDNNHSNDQQRGGSTGENNRNNLFSSGVASYRNQNGDVTTVE
LRNNNSAAFPPTDENPSQGQGSSSSDTTIHNDVPNDNNEQRSSQ"
gene complement(744311..746101)
/gene="MKC7"
/locus_tag="YDR144C"
/gene_synonym="YPS2"
/db_xref="GeneID:851722"
mRNA complement(744311..746101)
/gene="MKC7"
/locus_tag="YDR144C"
/gene_synonym="YPS2"
/product="Mkc7p"
/transcript_id="NM_001180451.3"
/db_xref="GI:398365834"
/db_xref="GeneID:851722"
CDS complement(744311..746101)
/gene="MKC7"
/locus_tag="YDR144C"
/gene_synonym="YPS2"
/EC_number="3.4.23.41"
/note="GPI-anchored aspartyl protease, member of the
yapsin family of proteases involved in cell wall growth
and maintenance; shares functions with Yap3p and Kex2p"
/codon_start=1
/product="Mkc7p"
/protein_id="NP_010428.3"
/db_xref="GI:398365835"
/db_xref="SGD:S000002551"
/db_xref="GeneID:851722"
/translation="MKLSVLTFVVDALLVCSSIVDAGVTDFPSLPSNEVYVKMNFQKK
YGSSFENALDDTKGRTRLMTRDDDYELVELTNQNSFYSVELDIGTPPQKVTVLVDTGS
SDLWVTGSDNPYCSTKKKDTTGSSFKQVNKDALASVVESVFTEISYDTTIVTSEATAT
FDSTASTSQLIDCATYGTFNTSKSSTFNSNNTEFSIAYGDTTFASGTWGHDQLSLNDL
NITGLSFAVANETNSTVGVLGIGLPGLESTYSGVSLSSVQKSYTYNNFPMVLKNSGVI
KSTAYSLFANDSDSKHGTILFGAVDHGKYAGDLYTIPIINTLQHRGYKDPIQFQVTLQ
GLGTSKGDKEDNLTTLTTTKIPVLLDSGTTISYMPTELVKMLADQVGATYSSAYGYYI
MDCIKEMEEESSIIFDFGGFYLSNWLSDFQLVTDSRSNICILGIAPQSDPTIILGDNF
LANTYVVYDLDNMEISMAQANFSDDGEYIEIIESAVPSALKAPGYSSTWSTYESIVSG
GNMFSTAANSSISYFASTSHSATSSSSSKGQKTQTSTTALSISKSTSSTSSTGMLSPT
SSSSTRKENGGHNLNPPFFARFITAIFHHI"
gene 746738..748357
/gene="TAF12"
/locus_tag="YDR145W"
/gene_synonym="TAF61; TAF68"
/db_xref="GeneID:851723"
mRNA 746738..748357
/gene="TAF12"
/locus_tag="YDR145W"
/gene_synonym="TAF61; TAF68"
/product="Taf12p"
/transcript_id="NM_001180452.1"
/db_xref="GI:296143496"
/db_xref="GeneID:851723"
CDS 746738..748357
/gene="TAF12"
/locus_tag="YDR145W"
/gene_synonym="TAF61; TAF68"
/note="Subunit (61/68 kDa) of TFIID and SAGA complexes,
involved in RNA polymerase II transcription initiation and
in chromatin modification, similar to histone H2A"
/codon_start=1
/product="Taf12p"
/protein_id="NP_010429.1"
/db_xref="GI:6320349"
/db_xref="SGD:S000002552"
/db_xref="GeneID:851723"
/translation="MSSNPENSGVNANNNTGTGNADAITGAQQNMVLQPRQLQEMAAK
FRTLLTEARNVGETTPRGKELMFQAAKIKQVYDALTLNRRRQQAAQAYNNTSNSNSSN
PASIPTENVPNSSQQQQQQQQQTRNNSNKFSNMIKQVLTPEENQEYEKLWQNFQVRHT
SIKEKETYLKQNIDRLEQEINKQTDEGPKQQLQEKKIELLNDWKVLKIEYTKLFNNYQ
NSKKTFYVECARHNPALHKFLQESTQQQRVQQQRVQQQQQQQQQQQQQQQQQQQQQQQ
RQGQNQRKISSSNSTEIPSVTGPDALKSQQQQQNTITATNNPRGNVNTSQTEQSKAKV
TNVNATASMLNNISSSKSAIFKQTEPAIPISENISTKTPAPVAYRSNRPTITGGSAMN
ASALNTPATTKLPPYEMDTQRVMSKRKLRELVKTVGIDEGDGETVIDGDVEELLLDLA
DDFVTNVTAFSCRLAKHRKSDNLEARDIQLHLERNWNIRIPGYSADEIRSTRKWNPSQ
NYNQKLQSITSDKVAAAKNNGNNVASLNTKK"
rep_origin 748392..748637
/note="ARS451;
Autonomously Replicating Sequence"
/db_xref="SGD:S000119070"
gene complement(748613..750742)
/gene="SWI5"
/locus_tag="YDR146C"
/db_xref="GeneID:851724"
mRNA complement(748613..750742)
/gene="SWI5"
/locus_tag="YDR146C"
/product="Swi5p"
/transcript_id="NM_001180453.1"
/db_xref="GI:296143497"
/db_xref="GeneID:851724"
CDS complement(748613..750742)
/gene="SWI5"
/locus_tag="YDR146C"
/note="Transcription factor that recruits Mediator and
Swi/Snf complexes; activates transcription of genes
expressed at the M/G1 phase boundary and in G1 phase;
required for expression of the HO gene controlling mating
type switching; localization to nucleus occurs during G1
and appears to be regulated by phosphorylation by Cdc28p
kinase; SWI5 has a paralog, ACE2, that arose from the
whole genome duplication"
/codon_start=1
/product="Swi5p"
/protein_id="NP_010430.1"
/db_xref="GI:6320350"
/db_xref="SGD:S000002553"
/db_xref="GeneID:851724"
/translation="MDTSNSWFDASKVQSLNFDLQTNSYYSNARGSDPSSYAIEGEYK
TLATDDLGNILNLNYGETNEVIMNEINDLNLPLGPLSDEKSVKVSTFSELIGNDWQSM
NFDLENNSREVTLNATSLLNENRLNQDSGMTVYQKTMSDKPHDEKKISMADNLLSTIN
KSEINKGFDRNLGELLLQQQQELREQLRAQQEANKKLELELKQTQYKQQQLQATLENS
DGPQFLSPKRKISPASENVEDVYANSLSPMISPPMSNTSFTGSPSRRNNRQKYCLQRK
NSSGTVGPLCFQELNEGFNDSLISPKKIRSNPNENLSSKTKFITPFTPKSRVSSATSN
SANITPNNLRLDFKINVEDQESEYSEKPLGLGIELLGKPGPSPTKSVSLKSASVDIMP
TIPGSVNNTPSVNKVSLSSSYIDQYTPRGKQLHFSSISENALGINAATPHLKPPSQQA
RHREGVFNDLDPNVLTKNTDNEGDDNEENEPESRFVISETPSPVLKSQSKYEGRSPQF
GTHIKEINTYTTNSPSKITRKLTTLPRGSIDKYVKEMPDKTFECLFPGCTKTFKRRYN
IRSHIQTHLEDRPYSCDHPGCDKAFVRNHDLIRHKKSHQEKAYACPCGKKFNREDALV
VHRSRMICSGGKKYENVVIKRSPRKRGRPRKDGTSSVSSSPIKENINKDHNGQLMFKL
EDQLRRERSYDGNGTGIMVSPMKTNQR"
gene 751631..753235
/gene="EKI1"
/locus_tag="YDR147W"
/db_xref="GeneID:851725"
mRNA 751631..753235
/gene="EKI1"
/locus_tag="YDR147W"
/product="bifunctional choline kinase/ethanolamine kinase
EKI1"
/transcript_id="NM_001180454.3"
/db_xref="GI:398365848"
/db_xref="GeneID:851725"
CDS 751631..753235
/gene="EKI1"
/locus_tag="YDR147W"
/EC_number="2.7.1.82"
/note="Ethanolamine kinase; primarily responsible for
phosphatidylethanolamine synthesis via the
CDP-ethanolamine pathway; exhibits some choline kinase
activity, thus contributing to phosphatidylcholine
synthesis via the CDP-choline pathway; EKI1 has a paralog,
CKI1, that arose from the whole genome duplication"
/codon_start=1
/product="bifunctional choline kinase/ethanolamine kinase
EKI1"
/protein_id="NP_010431.3"
/db_xref="GI:398365849"
/db_xref="SGD:S000002554"
/db_xref="GeneID:851725"
/translation="MYTNYSLTSSDAMPRTYLVGTASPEMSKKKRQSANCDKPTRRVI
HIIDTNEHSEVDLKNELPITCTNEDGEMTSSSWTSQTANDFLKLAYVNAKLDPSLPSQ
YFKQDIINVLQSLEIPGWSVPGSKESSLNKNLLTLTQIKGALTNVIYKIHYPNLPPLL
MRIFGDSIDSVIDREYELKVIARLSFYDLGPKLEGFFENGRFEKYIEGSRTSTQADFI
DRDTSIKIAKKLKELHCTVPLTHKEITDQPSCWTTFDQWIKLIDSHKEWVSNNVNISE
NLRCSSWNFFLKSFKNYKRWLYNDSAFTSKLLREDDKDSMINSGLKMVFCHNDLQHGN
LLFKSKGKDDISVGDLTIIDFEYAGPNPVVFDLSNHLNEWMQDYNDVQSFKSHIDKYP
KEEDILVFAQSYINHMNENHVKIASQEVRILYNLIIEWRPCTQLFWCLWALLQSGRLP
QRPLIEGEKLMSEKAGLGDETHLMEHKNKENGKYDCSEDDSFNYLGFCKEKMSVFWGD
LITLGVIDKDCPDIGKTDYLDTKLIF"
rep_origin 753167..753398
/note="ARS423;
Autonomously Replicating Sequence"
/db_xref="SGD:S000118438"
gene complement(753675..755066)
/gene="KGD2"
/locus_tag="YDR148C"
/db_xref="GeneID:851726"
mRNA complement(753675..755066)
/gene="KGD2"
/locus_tag="YDR148C"
/product="alpha-ketoglutarate dehydrogenase KGD2"
/transcript_id="NM_001180455.3"
/db_xref="GI:398365854"
/db_xref="GeneID:851726"
CDS complement(753675..755066)
/gene="KGD2"
/locus_tag="YDR148C"
/EC_number="2.3.1.61"
/note="Dihydrolipoyl transsuccinylase, component of the
mitochondrial alpha-ketoglutarate dehydrogenase complex,
which catalyzes the oxidative decarboxylation of
alpha-ketoglutarate to succinyl-CoA in the TCA cycle;
phosphorylated"
/codon_start=1
/product="alpha-ketoglutarate dehydrogenase KGD2"
/protein_id="NP_010432.3"
/db_xref="GI:398365855"
/db_xref="SGD:S000002555"
/db_xref="GeneID:851726"
/translation="MLSRATRTAAAKSLVKSKVARNVMAASFVKRHASTSLFKQANKV
ESLGSIYLSGKKISVAANPFSITSNRFKSTSIEVPPMAESLTEGSLKEYTKNVGDFIK
EDELLATIETDKIDIEVNSPVSGTVTKLNFKPEDTVTVGEELAQVEPGEAPAEGSGES
KPEPTEQAEPSQGVAARENSSEETASKKEAAPKKEAAPKKEVTEPKKADQPKKTVSKA
QEPPVASNSFTPFPRTETRVKMNRMRLRIAERLKESQNTAASLTTFNEVDMSALMEMR
KLYKDEIIKKTGTKFGFMGLFSKACTLAAKDIPAVNGAIEGDQIVYRDYTDISVAVAT
PKGLVTPVVRNAESLSVLDIENEIVRLSHKARDGKLTLEDMTGGTFTISNGGVFGSLY
GTPIINSPQTAVLGLHGVKERPVTVNGQIVSRPMMYLALTYDHRLLDGREAVTFLKTV
KELIEDPRKMLLW"
gene 755628..763874
/gene="NUM1"
/locus_tag="YDR150W"
/gene_synonym="PAC12"
/db_xref="GeneID:851727"
mRNA 755628..763874
/gene="NUM1"
/locus_tag="YDR150W"
/gene_synonym="PAC12"
/product="Num1p"
/transcript_id="NM_001180457.1"
/db_xref="GI:296143500"
/db_xref="GeneID:851727"
CDS 755628..763874
/gene="NUM1"
/locus_tag="YDR150W"
/gene_synonym="PAC12"
/note="Protein required for nuclear migration, localizes
to the mother cell cortex and the bud tip; may mediate
interactions of dynein and cytoplasmic microtubules with
the cell cortex"
/codon_start=1
/product="Num1p"
/protein_id="NP_010434.1"
/db_xref="GI:6320353"
/db_xref="SGD:S000002557"
/db_xref="GeneID:851727"
/translation="MSHNNRHKKNNDKDSSAGQYANSIDNSLSQESVSTNGVTRMANL
KADECGSGDEGDKTKRFSISSILSKRETKDVLPEFAGSSSHNGVLTANSSKDMNFTLE
LSENLLVECRKLQSSNEAKNEQIKSLKQIKESLSDKIEELTNQKKSFMKELDSTKDLN
WDLESKLTNLSMECRQLKELKKKTEKSWNDEKESLKLLKTDLEILTLTKNGMENDLSS
QKLHYDKEISELKERILDLNNENDRLLISVSDLTSEINSLQSNRTERIKIQKQLDDAK
ASISSLKRKVQKKYYQKQHTSDTTVTSDPDSEGTTSEEDIFDIVIEIDHMIETGPSVE
DISEDLVKKYSEKNNMILLSNDSYKNLLQKSESASKPKDDELMTKEVAENLNMIALPN
DDNYSKKEFSLESHIKYLEASGYKVLPLEEFENLNESLSNPSYNYLKEKLQALKKIPI
DQSTFNLLKEPTIDFLLPLTSKIDCLIIPTKDYNDLFESVKNPSIEQMKKCLEAKNDL
QSNICKWLEERNGCKWLSNDLYFSMVNKIETPSKQYLSDKAKEYDQVLIDTKALEGLK
NPTIDFLREKASASDYLLLKKEDYVSPSLEYLVEHAKATNHHLLSDSAYEDLVKCKEN
PDMEFLKEKSAKLGHTVVSNEAYSELEKKLEQPSLEYLVEHAKATNHHLLSDSAYEDL
VKCKENPDMEFLKEKSAKLGHTVVSNEAYSELQRKYSELEKEVEQPSLAYLVEHAKAT
DHHLLSDSAYEDLVKCKENPDVEFLKEKSAKLGHTVVSSEEYSELQRKYSELEKEVEQ
PSLAYLVEHAKATDHHLLSDSAYEELVKCKENPDMEFLKEKSAKLGHTVVSNEAYSEL
EKKLEQPSLAYLVEHAKATDHHLLSDSAYEDLVKCKENSDVEFLKEKSAKLGHTVVSN
EAYSELEKKLEQPSLAYLVEHAKATDHHLLSDSAYEDLVKCKENPDMEFLKEKSAKLG
HTVVSNEAYSELEKKLEQPSLEYLVEHAKATNHHLLSDSAYEDLVKCKENPDMEFLKE
KSAKLGHTVVSNEAYSELEKKLEQPSLEYLVEHAKATNHHLLSDSAYEELVKCKENPD
VEFLKEKSAKLGHTVVSNEAYSELEKKLEQPSLEYLVEHAKATNHHLLSDSAYEELVK
CKENPDVEFLKEKSAKLGHTVVSNEAYSELEKKLEQPSLAYLVEHAKATDHHLLSDSA
YEDLVKCKENPDVEFLKEKSAKLGHTVVSNEAYSELEKKLEQPSLAYLVEHAKATDHH
LLSDSAYEDLVKCKENPDMEFLKEKSAKLGHTVVSNEAYSELEKKLEQPSLEYLVEHA
KATNHHLLSDSAYEDLVKCKENPDMEFLKEKSAKLGHTVVSNKEYSELEKKLEQPSLE
YLVKHAEQIQSKIISISDFNTLANPSMEDMASKLQKLEYQIVSNDEYIALKNTMEKPD
VELLRSKLKGYHIIDTTTYNELVSNFNSPTLKFIEEKAKSKGYRLIEPNEYLDLNRIA
TTPSKEEIDNFCKQIGCYALDSKEYERLKNSLENPSKKFIEENAALLDLVLVDKTEYQ
AMKDNASNKKSLIPSTKALDFVTMPAPQLASAEKSSLQKRTLSDIENELKALGYVAIR
KENLPNLEKPIVDNASKNDVLNLCSKFSLVPLSTEEYDNMRKEHTKILNILGDPSIDF
LKEKCEKYQMLIISKHDYEEKQEAIENPGYEFILEKASALGYELVSEVELDRMKQMID
SPDIDYMQEKAARNEMVLLRNEEKEALQKKIEYPSLTFLIEKAAGMNKILVDQIEYDE
TIRKCNHPTRMELEESCHHLNLVLLDQNEYSTLREPLENRNVEDLINTLSKLNYIAIP
NTIYQDLIGKYENPNFDYLKDSLNKMDYVAISRQDYELMVAKYEKPQLDYLKISSEKI
DHIVVPLSEYNLMVTNYRNPSLSYLKEKAVLNNHILIKEDDYKNILAVSEHPTVIHLS
EKASLLNKVLVDKDDFATMSRSIEKPTIDFLSTKALSMGKILVNESTHKRNEKLLSEP
DSEFLTMKAKEQGLIIISEKEYSELRDQIDRPSLDVLKEKAAIFDSIIVENIEYQQLV
NTTSPCPPITYEDLKVYAHQFGMELCLQKPNKLSGAERAERIDEQSINTTSSNSTTTS
SMFTDALDDNIEELNRVELQNNEDYTDIISKSSTVKDATIFIPAYENIKNSAEKLGYK
LVPFEKSNINLKNIEAPLFSKDNDDTSVASSIDLDHLSRKAEKYGMTLISDQEFEEYH
ILKDNAVNLNGGMEEMNNPLSENQNLAAKTTNTAQEGAFQNTVPHNDMDNEEVEYGPD
DPTFTVRQLKKPAGDRNLILTSREKTLLSRDDNIMSQNEAVYGDDISDSFVDESQEIK
NDVDIIKTQAMKYGMLCIPESNFVGASYASAQDMSDIVVLSASYYHNLMSPEDMKWNC
VSNEELQAEVKKRGLQIALTTKEDKKGQATASKHEYVSHKLNNKTSTVSTKSGAKKGL
AEAAATTAYEDSESHPQIEEQSHRTNHHKHHKRQQSLNSNSTSKTTHSSRNTPASRRD
IVASFMSRAGSASRTASLQTLASLNEPSIIPALTQTVIGEYLFKYYPRLGPFGFESRH
ERFFWVHPYTLTLYWSASNPILENPANTKTKGVAILGVESVTDPNPYPTGLYHKSIVV
TTETRTIKFTCPTRQRHNIWYNSLRYLLQRNMQGISLEDIADDPTDNMYSGKIFPLPG
ENTKSSSKRLSASRRSVSTRSLRHRVPQSRSFGNLR"
gene complement(764178..765155)
/gene="CTH1"
/locus_tag="YDR151C"
/db_xref="GeneID:851729"
mRNA complement(764178..765155)
/gene="CTH1"
/locus_tag="YDR151C"
/product="Cth1p"
/transcript_id="NM_001180458.1"
/db_xref="GI:296143501"
/db_xref="GeneID:851729"
CDS complement(764178..765155)
/gene="CTH1"
/locus_tag="YDR151C"
/note="Member of the CCCH zinc finger family; has
similarity to mammalian Tis11 protein, which activates
transcription and also has a role in mRNA degradation; may
function with Tis11p in iron homeostasis"
/codon_start=1
/product="Cth1p"
/protein_id="NP_010435.1"
/db_xref="GI:6320355"
/db_xref="SGD:S000002558"
/db_xref="GeneID:851729"
/translation="MMPNVAPNSYYLNIPNANSTSTTTSSIFSDLNKEYESKIKEIEE
YYIKTLLNENTDNDDSSSSEGHNINETDILSEYSPRPSPWLPSKPNCYHPLGDFKDLI
ISDSRPTNTLPINNPFAGNNNISTLATTEKKRKKRSLEVEINPTYTTSAFSLPLTAEN
LQKLSQVDSQSTGLPYTLPIQKTTKLEPCRRAPLQLPQLVNKTLYKTELCESFTIKGY
CKYGNKCQFAHGLNELKFKKKSNNYRTKPCINWSKLGYCPYGKRCCFKHGDDKDVEIY
QNANDGRSKDTALTPLPTSLAPSNNDNITNLSKPRNLHTSVKALQRMTW"
gene 765706..766503
/gene="GIR2"
/locus_tag="YDR152W"
/db_xref="GeneID:851730"
mRNA 765706..766503
/gene="GIR2"
/locus_tag="YDR152W"
/product="Gir2p"
/transcript_id="NM_001180459.3"
/db_xref="GI:398365864"
/db_xref="GeneID:851730"
CDS 765706..766503
/gene="GIR2"
/locus_tag="YDR152W"
/note="Highly-acidic cytoplasmic RWD domain-containing
hypothetical protein; forms a complex with Rbg2p;
interacts with Rbg1p and Gcn1p; associates with
translating ribosomes; putative intrinsically unstructured
protein"
/codon_start=1
/product="Gir2p"
/protein_id="NP_010436.3"
/db_xref="GI:398365865"
/db_xref="SGD:S000002559"
/db_xref="GeneID:851730"
/translation="MDYKEEQKQELEVLESIYPDELRIINDEYPKIKFEVAIKLELDT
GDSTSVLTKEHTIIAEFKLPENYPDEPCLISLEAQEVALNDNEEDNEEDEDEVEYDDH
GNKVLKKFENLPDLISFKGYLPELTVQLESQIETDMLLGMQMCFALISSIKERCEQWY
SEQLNKLEKQYELEAQEREKKEQAKFHGTKVTRESYLEWRSKFRQELKLDERDQVRRM
KAHHGKLTGKQMFEQGVVGTGDEYMEEDDASVDDVAKGLAKTEIANQ"
gene complement(766736..767971)
/gene="ENT5"
/locus_tag="YDR153C"
/db_xref="GeneID:851731"
mRNA complement(766736..767971)
/gene="ENT5"
/locus_tag="YDR153C"
/product="Ent5p"
/transcript_id="NM_001180460.3"
/db_xref="GI:398365866"
/db_xref="GeneID:851731"
CDS complement(766736..767971)
/gene="ENT5"
/locus_tag="YDR153C"
/note="Protein containing an N-terminal epsin-like domain
involved in clathrin recruitment and traffic between the
Golgi and endosomes; associates with the clathrin adaptor
Gga2p, clathrin adaptor complex AP-1, and clathrin"
/codon_start=1
/product="Ent5p"
/protein_id="NP_010437.3"
/db_xref="GI:398365867"
/db_xref="SGD:S000002560"
/db_xref="GeneID:851731"
/translation="MDSLSKKIQNLGIHDIRNAARFAQNVIVQYEPYQIDIRRATNTD
AWGPTPKHLAKVLRNRYQVPLYLMTEYTLKRLVDHIATRPKNLYEKARKDYVNYGSEW
RVVLKCLVVIEFLLLNVDTGDELNQIRSCLLTHKHILTREIAQFKVKFSNDGKMEIHE
RGIRKKGELILQYLEDSQFLKKERAKNKKNALKIRQQGESSIYNANQISTSASYDNID
DDEFDADADGFDSEMDANNVTNFNVPVETEANSNTRRRSHMEEQRRQRREILREQIKN
KEQQRKRKQQQDSIPDLIDLDDSTSTTNNITIDNGNNDNKNNNINSNSDDDDDEFGDF
QSETSPDTTAPKTSNSKIDDLLDWDGPKSDTDTTAAAQTSLPFAEKKQQKARPQATKD
KSKGNDAFSDLFSYSKSLV"
gene complement(768512..769000)
/gene="CPR1"
/locus_tag="YDR155C"
/gene_synonym="CPH1; CYP1"
/db_xref="GeneID:851733"
mRNA complement(768512..769000)
/gene="CPR1"
/locus_tag="YDR155C"
/gene_synonym="CPH1; CYP1"
/product="peptidylprolyl isomerase CPR1"
/transcript_id="NM_001180462.1"
/db_xref="GI:296143504"
/db_xref="GeneID:851733"
CDS complement(768512..769000)
/gene="CPR1"
/locus_tag="YDR155C"
/gene_synonym="CPH1; CYP1"
/EC_number="5.2.1.8"
/note="Cytoplasmic peptidyl-prolyl cis-trans isomerase
(cyclophilin); catalyzes the cis-trans isomerization of
peptide bonds N-terminal to proline residues; binds the
drug cyclosporin A; protein abundance increases in
response to DNA replication stress"
/codon_start=1
/product="peptidylprolyl isomerase CPR1"
/protein_id="NP_010439.1"
/db_xref="GI:6320359"
/db_xref="SGD:S000002562"
/db_xref="GeneID:851733"
/translation="MSQVYFDVEADGQPIGRVVFKLYNDIVPKTAENFRALCTGEKGF
GYAGSPFHRVIPDFMLQGGDFTAGNGTGGKSIYGGKFPDENFKKHHDRPGLLSMANAG
PNTNGSQFFITTVPCPWLDGKHVVFGEVVDGYDIVKKVESLGSPSGATKARIVVAKSG
EL"
gene 769525..769938
/gene="RPA14"
/locus_tag="YDR156W"
/db_xref="GeneID:851734"
mRNA 769525..769938
/gene="RPA14"
/locus_tag="YDR156W"
/product="Rpa14p"
/transcript_id="NM_001180463.1"
/db_xref="GI:296143505"
/db_xref="GeneID:851734"
CDS 769525..769938
/gene="RPA14"
/locus_tag="YDR156W"
/note="RNA polymerase I subunit A14"
/codon_start=1
/product="Rpa14p"
/protein_id="NP_010440.1"
/db_xref="GI:6320360"
/db_xref="SGD:S000002563"
/db_xref="GeneID:851734"
/translation="MMKGSRRTGNNTATTLNTPVVIHATQLPQHVSTDEVLQFLESFI
DEKENIIDSTTMNTISGNAADADAAAVANTSLNIDTNLSSSISQLKRIQRDFKGLPPA
QDFSAAPIQVSTTEKKETSIGVSATGGKKTTFADE"
gene 770357..771454
/gene="HOM2"
/locus_tag="YDR158W"
/gene_synonym="THR2"
/db_xref="GeneID:851736"
mRNA 770357..771454
/gene="HOM2"
/locus_tag="YDR158W"
/gene_synonym="THR2"
/product="aspartate-semialdehyde dehydrogenase"
/transcript_id="NM_001180465.3"
/db_xref="GI:398365876"
/db_xref="GeneID:851736"
CDS 770357..771454
/gene="HOM2"
/locus_tag="YDR158W"
/gene_synonym="THR2"
/EC_number="1.2.1.11"
/note="Aspartic beta semi-aldehyde dehydrogenase,
catalyzes the second step in the common pathway for
methionine and threonine biosynthesis; expression
regulated by Gcn4p and the general control of amino acid
synthesis"
/codon_start=1
/product="aspartate-semialdehyde dehydrogenase"
/protein_id="NP_010442.3"
/db_xref="GI:398365877"
/db_xref="SGD:S000002565"
/db_xref="GeneID:851736"
/translation="MAGKKIAGVLGATGSVGQRFILLLANHPHFELKVLGASSRSAGK
KYVDAVNWKQTDLLPESATDIIVSECKSEFFKECDIVFSGLDADYAGAIEKEFMEAGI
AIVSNAKNYRREQDVPLIVPVVNPEHLDIVAQKLDTAKAQGKPRPGFIICISNCSTAG
LVAPLKPLIEKFGPIDALTTTTLQAISGAGFSPGVPGIDILDNIIPYIGGEEDKMEWE
TKKILAPLAEDKTHVKLLTPEEIKVSAQCNRVAVSDGHTECISLRFKNRPAPSVEQVK
TCLKEYVCDAYKLGCHSAPKQTIHVLEQPDRPQPRLDRNRDSGYGVSVGRIREDPLLD
FKMVVLSHNTIIGAAGSGVLIAEILLARNLI"
gene 771877..775782
/gene="SAC3"
/locus_tag="YDR159W"
/gene_synonym="LEP1"
/db_xref="GeneID:851737"
mRNA 771877..775782
/gene="SAC3"
/locus_tag="YDR159W"
/gene_synonym="LEP1"
/product="Sac3p"
/transcript_id="NM_001180466.3"
/db_xref="GI:398365882"
/db_xref="GeneID:851737"
CDS 771877..775782
/gene="SAC3"
/locus_tag="YDR159W"
/gene_synonym="LEP1"
/note="Nuclear pore-associated protein; required for
biogenesis of the small ribosomal subunit; component of
TREX-2 complex (Sac3p-Thp1p-Sus1p-Cdc31p) involved in
transcription elongation and mRNA export from the nucleus;
involved in post-transcriptional tethering of active genes
to the nuclear periphery and to non-nascent mRNP; similar
to the human germinal center-associated nuclear protein
(GANP)"
/codon_start=1
/product="Sac3p"
/protein_id="NP_010443.3"
/db_xref="GI:398365883"
/db_xref="SGD:S000002566"
/db_xref="GeneID:851737"
/translation="MNTSFGSVVPSTNFNFFKGHGNNDNTSANSTVNNSNFFLNSNET
KPSKNVFMVHSTSQKKSQQPLQNLSHSPSYTENKPDKKKKYMINDAKTIQLVGPLISS
PDNLGFQKRSHKARELPRFLINQEPQLEKRAFVQDPWDKANQEKMISLEESIDDLNEL
YETLKKMRNTERSIMEEKGLVDKADSAKDLYDAIVFQGTCLDMCPTFERSRRNVEYTV
YSYEKNQPNDKKASRTKALKVFARPAAAAAPPLPSDVRPPHILVKTLDYIVDNLLTTL
PESEGFLWDRMRSIRQDFTYQNYSGPEAVDCNERIVRIHLLILHIMVKSNVEFSLQQE
LEQLHKSLITLSEIYDDVRSSGGTCPNEAEFRAYALLSKIRDPQYDENIQRLPKHIFQ
DKLVQMALCFRRVISNSAYTERGFVKTENCLNFYARFFQLMQSPSLPLLMGFFLQMHL
TDIRFYALRALSHTLNKKHKPIPFIYLENMLLFNNRQEIIEFCNYYSIEIINGDAADL
KTLQHYSHKLSETQPLKKTYLTCLERRLQKTTYKGLINGGEDNLASSVYVKDPKKDRI
PSIADQSFLMENFQNNYNEKLNQNSSVKPQINTSPKRVATRPNHFPFSQESKQLPQIS
QSHTLSTNPLLTPQVHGDLSEQKQQQIKTVTDGGSPFVFDQSAQNSTVEASKAHMIST
TSNGAYDEKLSSEQEEMRKKEEQRIEEEKTQLKKKQENADKQVITEQIANDLVKEVVN
SSVISIVKREFSEANYRKDFIDTMTRELYDAFLHERLYLIYMDSRAELKRNSTLKKKF
FEKWQASYSQAKKNRILEEKKREEIKLVSHQLGVPGFKKSTCLFRTPYKGNVNSSFML
SSSDKNLIFSPVNDEFNKFATHLTKISKLWRPLEMQSIYYDNLTKKFPSNSLTPANLF
IYAKDWTSLSNRWILSKFNLQTAQDSKKFSNNIISSRIICIDDEYEPSDFSDLQLLIF
NTGVTNPDIFDLEMKLKDDGEELIKLITGISLNTNICFSLLIIYWESAENTLSESTIK
HLLKLNRISKNYSSVIERIDLMNLTEESPHKCLEDKLSEISHSYVYKLTERGKYDKTL
RQKRSLAGIHSRSTQLQTTKDIDQKMKKMLEKEKNKYQQQIGERNTYAHLESHIDASP
RSKKRKLPILLSTSHSSQFKTPLASRLNTSGSSTSPPLPSHLAMKFRKNSRVTSLHTV
LPVSTPSHSNNIPAASFSGNNTTDIQSQQLIENQKSTSVYLNNVSERILGNQEICQTP
INPVTPVLDGADQGKEDIPDSILELKILIDSVKKKVNND"
gene 776163..778721
/gene="SSY1"
/locus_tag="YDR160W"
/gene_synonym="RAA1; SHR10"
/db_xref="GeneID:851738"
mRNA 776163..778721
/gene="SSY1"
/locus_tag="YDR160W"
/gene_synonym="RAA1; SHR10"
/product="Ssy1p"
/transcript_id="NM_001180467.1"
/db_xref="GI:296143508"
/db_xref="GeneID:851738"
CDS 776163..778721
/gene="SSY1"
/locus_tag="YDR160W"
/gene_synonym="RAA1; SHR10"
/note="Component of the SPS plasma membrane amino acid
sensor system (Ssy1p-Ptr3p-Ssy5p), which senses external
amino acid concentration and transmits intracellular
signals that result in regulation of expression of amino
acid permease genes"
/codon_start=1
/product="Ssy1p"
/protein_id="NP_010444.1"
/db_xref="GI:6320364"
/db_xref="SGD:S000002567"
/db_xref="GeneID:851738"
/translation="MSSVNQIYDLFPNKHNIQFTDSHSQEHDTSSSLAKNDTDGTISI
PGSIDTGILKSIIEEQGWNDAELYRSSIQNQRFFLTDKYTKKKHLTMEDMLSPEEEQI
YQEPIQDFQTYNKRVQREYELRERMEEFFRQNTKNDLHILNEDSLNQQYSPLGPADYV
LPLDRYSRMKHIASNFFRKKLGIPRKLKRRSHYNPNAEGHTKGNSSILSSTTDVIDNA
SYRNIAIDENVDITHKEHAIDEINEQGASGSESVVEGGSLLHDIEKVFNRSRATRKYH
IQRKLKVRHIQMLSIGACFSVGLFLTSGKAFSIAGPFGTLLGFGLTGSIILATMLSFT
ELSTLIPVSSGFSGLASRFVEDAFGFALGWTYWISCMLALPAQVSSSTFYLSYYNNVN
ISKGVTAGFITLFSAFSIVVNLLDVSIMGEIVYVAGISKVIIAILMVFTMIILNAGHG
NDIHEGVGFRYWDSSKSVRNLTYGLYRPTFDLADAGEGSKKGISGPKGRFLATASVML
ISTFAFSGVEMTFLASGEAINPRKTIPSATKRTFSIVLISYVFLIFSVGINIYSGDPR
LLSYFPGISEKRYEAIIKGTGMDWRLRTNCRGGIDYRQISVGTGYSSPWVVALQNFGL
CTFASAFNAILIFFTATAGISSLFSCSRTLYAMSVQRKAPPVFEICSKRGVPYVSVIF
SSLFSVIAYIAVDQTAIENFDVLANVSSASTSIIWMGLNLSFLRFYYALKQRKDIISR
NDSSYPYKSPFQPYLAIYGLVGCSLFVIFMGYPNFIHHFWSTKAFFSAYGGLMFFFIS
YTAYKVLGTSKIQRLDQLDMDSGRREMDRTDWTEHSQYLGTYRERAKKLVTWLI"
gene 779043..780206
/locus_tag="YDR161W"
/db_xref="GeneID:851739"
mRNA 779043..780206
/locus_tag="YDR161W"
/product="hypothetical protein"
/transcript_id="NM_001180468.1"
/db_xref="GI:296143509"
/db_xref="GeneID:851739"
CDS 779043..780206
/locus_tag="YDR161W"
/note="hypothetical protein; non-essential gene; proposed
function in rRNA and ribosome biosynthesis based on
transcriptional co-regulation; genetic interactions
suggest a role in ER-associated protein degradation
(ERAD)"
/codon_start=1
/product="hypothetical protein"
/protein_id="NP_010445.1"
/db_xref="GI:6320365"
/db_xref="SGD:S000002568"
/db_xref="GeneID:851739"
/translation="MSELEATIRQAKEALAENNAKKALKILKPFKSSLKKENANNVIL
NEVFADAYLDNGQVEKAYPILARACELDPEGQVGGPDKFFTMGQIMGGQDGVSIITRG
IMNISNTGGEMLTNVQVEKIVGGLLSVIEIWMTDLCMEPNAEEQCEELIQKAMELTEG
KSPETWSTLGSIKISQQKFGEAYEAFSQAWNFFELKKQEIGSGINENGDTTQKAGLQS
EYVDLLQPLLSLTKMCLEVGAYEVALKVIAAVRDIDEDNIEGYYLEGFTYYLMSKLEI
FKLNNPEVSLRPENIYEFNQLIQEVPLDLSHEPISQLIYDSRLALSFALQAGVNADSK
DEIVQELLGGANALLQEIGGPLDPSELTQIKKGDLVNENEDLEELDIEEEYSD"
gene complement(780390..781100)
/gene="NBP2"
/locus_tag="YDR162C"
/db_xref="GeneID:851740"
mRNA complement(780390..781100)
/gene="NBP2"
/locus_tag="YDR162C"
/product="Nbp2p"
/transcript_id="NM_001180469.3"
/db_xref="GI:398365894"
/db_xref="GeneID:851740"
CDS complement(780390..781100)
/gene="NBP2"
/locus_tag="YDR162C"
/note="Protein involved in the HOG (high osmolarity
glycerol) pathway, negatively regulates Hog1p by
recruitment of phosphatase Ptc1p the Pbs2p-Hog1p complex,
found in the nucleus and cytoplasm, contains an SH3 domain
that binds Pbs2p"
/codon_start=1
/product="Nbp2p"
/protein_id="NP_010446.3"
/db_xref="GI:398365895"
/db_xref="SGD:S000002569"
/db_xref="GeneID:851740"
/translation="MATMETTTQKDTNILKSGLKKTIGVLNEAVLQNGREVEAVQAGN
SDTMEDTETTTIGYISIKDYAYADSNPLHYGYFDGDNEEDEMVSDSSNGEDTYNKRQS
ITLPDDYIVNQRAVALYDFEPENDNELRLAEGDIVFISYKHGQGWLVAENESGSKTGL
VPEEFVSYIQPEDGENEVENKARPFYLTHLITQSVSPKNNIDNTNEDEYDDNDEWEDI
DDVAEVEADMKTKLDISD"
gene 781423..781950
/gene="CWC15"
/locus_tag="YDR163W"
/db_xref="GeneID:851741"
mRNA 781423..781950
/gene="CWC15"
/locus_tag="YDR163W"
/product="Cwc15p"
/transcript_id="NM_001180470.3"
/db_xref="GI:398365896"
/db_xref="GeneID:851741"
CDS 781423..781950
/gene="CWC15"
/locus_tag="YDR163W"
/note="Non-essential protein involved in pre-mRNA
splicing, component of a complex containing Cef1p; has
similarity to S. pombe Cwf15p"
/codon_start=1
/product="Cwc15p"
/protein_id="NP_010447.3"
/db_xref="GI:398365897"
/db_xref="SGD:S000002570"
/db_xref="GeneID:851741"
/translation="MTTSHRPQLEARSGAKAAAYTPTGIEHARLLPGHTTLKYRKFKE
EENLRANCAQEDRSNDKSLEEAVMNEEKQDVVGSGNLQETRSEKDQKDSLQELLVTQK
NKVEDKAELEGNEQLKGGNSSRRSWRKGTAFGRHKVTKETNIKEHATKKSASGYINDM
TKSEYHQEFLHKHVR"
gene complement(782041..784215)
/gene="SEC1"
/locus_tag="YDR164C"
/db_xref="GeneID:851742"
mRNA complement(782041..784215)
/gene="SEC1"
/locus_tag="YDR164C"
/product="Sec1p"
/transcript_id="NM_001180471.1"
/db_xref="GI:296143512"
/db_xref="GeneID:851742"
CDS complement(782041..784215)
/gene="SEC1"
/locus_tag="YDR164C"
/note="Sm-like protein involved in docking and fusion of
exocytic vesicles; binds to assembled SNARE complexes at
the membrane and stimulates membrane fusion; localization
to sites of secretion (bud neck and bud tip) is dependent
on SNARE function"
/codon_start=1
/product="Sec1p"
/protein_id="NP_010448.1"
/db_xref="GI:6320368"
/db_xref="SGD:S000002571"
/db_xref="GeneID:851742"
/translation="MSDLIELQRNYLIGVLNQIETKNNLKFLIIDKTVETILSYLFLT
PQELLNNVTSVDLIDSPTRKGQSSIEAIYILEPTKYNINCIDADFMVRPPKYRRCHIR
FLPGLTNPIFQFFQSKRYIAQNLESFKPIELGFFVKESQFFETLQMEHSLQVFFNNNC
KALIPTNVRKIVGSLVSLCVITGEYPIVRYSVSNPVEEEDARNGNAVVNANSLTRSIA
NAFQIAIDTYARNNPDFPPQNTERPRSILIITDRTLDPFAPILHDFSYQAMAYDLVAN
VDTQKDIYHYSAENEAGEQEEKVSKLVDLYDPDWIDLKHQHIMDANEYIQGRIKELIA
KNPLLVDRSNVKNTTDLLSVVAHLKDFDEERRRLILHKTLVDECLGENAERKLADISA
IEQNLSGFGMDFSGEKIKHIIDDLLPALAMKEPTILDKLRYIIAYALFRGGIIELDFI
KLLNFIGVTHEHENFQQYLKIFRNYDLIDFKLIKDKPKDKPFQKEWFHDTLVNDPNIY
HTSRFVPAVGNILSKVIANPLLLSEQYFPYLKDKPIELLNEEEFQAGLANTSANSSSS
LRNPRHKAAWTTKSSNIKKNIPRQRFFYYVIGGISIPEIKAAYDQSNLKNRDIFIGSD
EILTPTKFLDEVERLQNPREFFKFKEDQRQQVNPPDFLLREMKPVAQPVSHVHLKSQD
NSPKSGTSSPKAAGSLKSEPPEKEKKRSKFSRFLKRKSHHDK"
gene 784871..786205
/gene="TRM82"
/locus_tag="YDR165W"
/db_xref="GeneID:851743"
mRNA 784871..786205
/gene="TRM82"
/locus_tag="YDR165W"
/product="Trm82p"
/transcript_id="NM_001180472.1"
/db_xref="GI:296143513"
/db_xref="GeneID:851743"
CDS 784871..786205
/gene="TRM82"
/locus_tag="YDR165W"
/note="Catalytic subunit of a tRNA methyltransferase
complex; Trm8p and Trm82p comprise an enzyme that
catalyzes a methyl-transfer from S-adenosyl-l-methionine
to the N(7) atom of guanine at position 46 in tRNA; Trm8
lacks catalytic activity if not bound to Trm82p"
/codon_start=1
/product="Trm82p"
/protein_id="NP_010449.1"
/db_xref="GI:6320369"
/db_xref="SGD:S000002572"
/db_xref="GeneID:851743"
/translation="MSVIHPLQNLLTSRDGSLVFAIIKNCILSFKYQSPNHWEFAGKW
SDDFDKIQESRNTTAKEQQGQSSENENENKKLKSNKGDSIKRTAAKVPSPGLGAPPIY
SYIRNLRLTSDESRLIACADSDKSLLVFDVDKTSKNVLKLRKRFCFSKRPNAISIAED
DTTVIIADKFGDVYSIDINSIPEEKFTQEPILGHVSMLTDVHLIKDSDGHQFIITSDR
DEHIKISHYPQCFIVDKWLFGHKHFVSSICCGKDYLLLSAGGDDKIFAWDWKTGKNLS
TFDYNSLIKPYLNDQHLAPPRFQNENNDIIEFAVSKIIKSKNLPFVAFFVEATKCIII
LEMSEKQKGDLALKQIITFPYNVISLSAHNDEFQVTLDNKESSGVQKNFAKFIEYNLN
ENSFVVNNEKSNEFDSAIIQSVQGDSNLVTKKEEIYPLYNVSSLRKHGEHYS"
gene complement(786306..789221)
/gene="SEC5"
/locus_tag="YDR166C"
/db_xref="GeneID:851744"
mRNA complement(786306..789221)
/gene="SEC5"
/locus_tag="YDR166C"
/product="Sec5p"
/transcript_id="NM_001180473.3"
/db_xref="GI:398365918"
/db_xref="GeneID:851744"
CDS complement(786306..789221)
/gene="SEC5"
/locus_tag="YDR166C"
/note="Essential 107kDa subunit of the exocyst complex
(Sec3p, Sec5p, Sec6p, Sec8p, Sec10p, Sec15p, Exo70p, and
Exo84p), which has the essential function of mediating
polarized targeting of secretory vesicles to active sites
of exocytosis"
/codon_start=1
/product="Sec5p"
/protein_id="NP_010450.3"
/db_xref="GI:398365919"
/db_xref="SGD:S000002573"
/db_xref="GeneID:851744"
/translation="MDRFQIGDEQLLRFYQLKTINPTHSWAQDSSKLNNEEATSNELG
VETSFDILKDFKYGNQISIDKESRAYLNDESLSYIRDPLNGQEMSKELQHLPNDSMRL
NYLVNSKQFNVKAFLRDMHKQDSFNDLNNSLDRLDSDIQDQSIHLKQLVGKNFTKYVK
IKNKLDQIYKEFDEKTNEKNQCDSPKENQINVESLNKKVDEVIRTTTFKLKPLMDNYQ
KILNYQATKKFIELNKFYFNLPKSLKRCLTNNDFNEFIIEYSKGLTLRRRFNQSSDAS
QSLVIKRIWTQIENLLVTYKDLIWNSLINSNFNIDQPQETILSLFSKLLNLENFINNN
QRESESGNKNTTSSSNENPILRWMSIKMNGFQNELNELSGHMISKIIHSQRLILQNNT
NQDKSQGCVELSYYLKINQLFQIISDTGKDSEGLKSTVEPNKVNTISGTSYLNLNCQP
SSQGLTDSPTIIEMWLLILKYINDLWKICDQFIEFWEHIEKFLDGTYQNSIINEKRKE
NILIGDSNIIESYQKSLILKEEQINEVRLKGEEFITSVSQNLISFFTSSQSSLPSSLK
DSTGDITRSNKDSGSPLDYGFIPPNCNGLSCLRYLPKIVEPILKFSTELAQLNITTNG
ITICRNTLSTIINRCVGAISSTKLRDISNFYQLENWQVYETVTFSSKSQDSSKNLTFE
YGVTQFPEIVTSFQEVSIKTTRDLLFAYEKLPIINGISVVSYPSKQLLTGIEIQQIIS
MEAVLEAILKNAAKDKDNPRNSHTILTLTNLQYFRECAFPNILQYFDDAFEWNLASKN
LELFSLLSKMESSIFGNYLSDLKINLRDTLEEKFHEINWPMYTSNSFRVGDYIIEALM
ILIVVHSECFRIGPQLIHKILIETQIFIARYLFEAFKPYVGNLSNDGSLQIIVDLEFF
QKVMGPLLEKDTEATLRACLQNCFQNDTNRLQKCINEINPIVSANLKRTAIQFAAFS"
gene 789449..790069
/gene="TAF10"
/locus_tag="YDR167W"
/gene_synonym="TAF23; TAF25"
/db_xref="GeneID:851745"
mRNA 789449..790069
/gene="TAF10"
/locus_tag="YDR167W"
/gene_synonym="TAF23; TAF25"
/product="Taf10p"
/transcript_id="NM_001180474.3"
/db_xref="GI:398365920"
/db_xref="GeneID:851745"
CDS 789449..790069
/gene="TAF10"
/locus_tag="YDR167W"
/gene_synonym="TAF23; TAF25"
/note="Subunit (145 kDa) of TFIID and SAGA complexes,
involved in RNA polymerase II transcription initiation and
in chromatin modification"
/codon_start=1
/product="Taf10p"
/protein_id="NP_010451.3"
/db_xref="GI:398365921"
/db_xref="SGD:S000002574"
/db_xref="GeneID:851745"
/translation="MDFEEDYDAEFDDNQEGQLETPFPSVAGADDGDNDNDDSVAENM
KKKQKREAVVDDGSENAFGIPEFTRKDKTLEEILEMMDSTPPIIPDAVIDYYLTKNGF
NVADVRVKRLLALATQKFVSDIAKDAYEYSRIRSSVAVSNANNSQARARQLLQGQQQP
GVQQISQQQHQQNEKTTASKVVLTVNDLSSAVAEYGLNIGRPDFYR"
gene 790328..791848
/gene="CDC37"
/locus_tag="YDR168W"
/gene_synonym="SMO1"
/db_xref="GeneID:851746"
mRNA 790328..791848
/gene="CDC37"
/locus_tag="YDR168W"
/gene_synonym="SMO1"
/product="Cdc37p"
/transcript_id="NM_001180475.1"
/db_xref="GI:296143516"
/db_xref="GeneID:851746"
CDS 790328..791848
/gene="CDC37"
/locus_tag="YDR168W"
/gene_synonym="SMO1"
/note="Essential Hsp90p co-chaperone; necessary for
passage through the START phase of the cell cycle;
stabilizes protein kinase nascent chains and participates
along with Hsp90p in their folding"
/codon_start=1
/product="Cdc37p"
/protein_id="NP_010452.1"
/db_xref="GI:6320372"
/db_xref="SGD:S000002575"
/db_xref="GeneID:851746"
/translation="MAIDYSKWDKIELSDDSDVEVHPNVDKKSFIKWKQQSIHEQRFK
RNQDIKNLETQVDMYSHLNKRVDRILSNLPESSLTDLPAVTKFLNANFDKMEKSKGEN
VDPEIATYNEMVEDLFEQLAKDLDKEGKDSKSPSLIRDAILKHRAKIDSVTVEAKKKL
DELYKEKNAHISSEDIHTGFDSSFMNKQKGGAKPLEATPSEALSSAAESNILNKLAKS
SVPQTFIDFKDDPMKLAKETEEFGKISINEYSKSQKFLLEHLPIISEQQKDALMMKAF
EYQLHGDDKMTLQVIHQSELMAYIKEIYDMKKIPYLNPMELSNVINMFFEKVIFNKDK
PMGKESFLRSVQEKFLHIQKRSKILQQEEMDESNAEGVETIQLKSLDDSTELEVNLPD
FNSKDPEEMKKVKVFKTLIPEKMQEAIMTKNLDNINKVFEDIPIEEAEKLLEVFNDID
IIGIKAILENEKDFQSLKDQYEQDHEDATMENLSLNDRDGGGDNHEEVKHTADTVD"
gene complement(792348..793889)
/gene="STB3"
/locus_tag="YDR169C"
/db_xref="GeneID:851747"
mRNA complement(792348..793889)
/gene="STB3"
/locus_tag="YDR169C"
/product="Stb3p"
/transcript_id="NM_001180476.1"
/db_xref="GI:296143517"
/db_xref="GeneID:851747"
CDS complement(792348..793889)
/gene="STB3"
/locus_tag="YDR169C"
/note="Ribosomal RNA processing element (RRPE)-binding
protein; involved in the glucose-induced transition from
quiescence to growth; restricted to nucleus in quiescent
cells, released into cytoplasm after glucose repletion;
binds Sin3p; relative distribution to the nucleus
increases upon DNA replication stress"
/codon_start=1
/product="Stb3p"
/protein_id="NP_010453.1"
/db_xref="GI:6320373"
/db_xref="SGD:S000002576"
/db_xref="GeneID:851747"
/translation="MSENQKEVSPPQAISVKSEASSSIFSKPISTSSPAGLAAAQRVT
PGKLSTLLLEMGPLAIRHITQTLCLDIPCFKDLSSSKQRRLIMSAMESGDKEKSVVFE
KIGWGQWSAKRVDPANFDKELEATNFANAKVKDLISQESQRRKSNNSNSNSGGKVEMP
MKVEHNITNIDGATTPPTAVASTTIPVNIKRSKSPLAAANVVYIDENALASEDEDEEF
DEDDHHLHYQNKSRNSSNNFGKSSNGDPYSFGRRRSQVVFADSTPENIEHEIIAQKIR
PLLRNRRRSSIKPHTPFISKLNTHQDSSYLSPNTTSTTTPSNNNSNSNQAKIDLEKLT
ATSEPTSRRASRLSVSKESSIRSTLFPNKNYLIVTTNPNSKATSVSTSPKLEEQMNVS
SNPIVLSDKEKHRVASQHLNGESSPQLVPHSHHQPHSDTDEEDWESIGAASLRNNSLA
PNIDSVASSTNGVVSPKPTNPSFTNSQNGDIEPPLQHDQQKHEQQPRNGEDNSAAFLL
MSLKS"
gene complement(794574..794723)
/locus_tag="YDR169C-A"
/db_xref="GeneID:1466433"
mRNA complement(794574..794723)
/locus_tag="YDR169C-A"
/product="hypothetical protein"
/transcript_id="NM_001184544.3"
/db_xref="GI:398365936"
/db_xref="GeneID:1466433"
CDS complement(794574..794723)
/locus_tag="YDR169C-A"
/note="hypothetical protein; identified by fungal homology
and RT-PCR"
/codon_start=1
/product="hypothetical protein"
/protein_id="NP_878062.3"
/db_xref="GI:398365937"
/db_xref="SGD:S000028538"
/db_xref="GeneID:1466433"
/translation="MMRMSLKQMQSQRFSATSRVRMLLIGASGLRSSSSKLECPRFSN
KHGRN"
gene complement(796193..802222)
/gene="SEC7"
/locus_tag="YDR170C"
/db_xref="GeneID:851748"
mRNA complement(796193..802222)
/gene="SEC7"
/locus_tag="YDR170C"
/product="Sec7p"
/transcript_id="NM_001180477.3"
/db_xref="GI:398365940"
/db_xref="GeneID:851748"
CDS complement(796193..802222)
/gene="SEC7"
/locus_tag="YDR170C"
/note="Guanine nucleotide exchange factor (GEF) for ADP
ribosylation factors involved in proliferation of the
Golgi, intra-Golgi transport and ER-to-Golgi transport;
found in the cytoplasm and on Golgi-associated coated
vesicles"
/codon_start=1
/product="Sec7p"
/protein_id="NP_010454.3"
/db_xref="GI:398365941"
/db_xref="SGD:S000002577"
/db_xref="GeneID:851748"
/translation="MSEQNSVVNAEKGDGEISSNVETASSVNPSVKPQNAIKEEAKET
NGEDQKCKGPENAGSTAETKETSNDATNGMKTPEETEDTNDKRHDDEGEDGDEDEDED
EDEDEDNGDEDDEDVDSSSSETSSEDGEDSESVSGESTESSSGEDEESDESDGNTSNS
SSGDESGSEEEEEEEEEEEEEENAGEPAIAHQDSVPTNDSTAPRSTHTRNISLSSNGS
NTNSTIILVKTTLETILNDKDIKKNSNAQKAIERTLQKFKEFDPQTTNNPHYVDSILV
FEALRASCRTKSSKVQSLALDCLSKLFSFRSLDETLLVNPPDSLASNDQRQDAADGIT
PPPKQKIIDAAIDTISDCFQGEGTDDRVELQIVRALSSCILEEDSSSLCHGASLLKAI
RTIYNVFVFSLNPSNQGIAQATLTQIISSVYDKIDLKQSTSSAVSLSTKNHQQQSAIE
LSEASENAETPAPLTLENMDKLNDDEERLMDAQQPDSIAITNQDLAVKDAFLVFRVMA
KICAKPLETELDMRSHAVRSKLLSLHIIYSIIKDHIDVFLSHNIFLPGKERVCFIDSI
RQYLRLVLSRNAASPLAPVFEVTLEIMWLLIANLRADFVKEIPVFLTEIYFPISELTT
STSQQKRYFLSVIQRICNDPRTLVEFYLNYDCNPGMPNVMEITVDYLTRLALTRVEIT
QTQRSYYDEQISKSLSTYNFSQLPLLTSSNLSSSPDVGQVNLLFPLDFALKMVSLNCI
VSVLRSLSSWAHKALNPNTHTANKVLLNTTSSARQESRSSLSNDVRSSIMTSNDDFKP
TYEDEESRSLSSQNIDADDPTQFENLKLRKTALSECIAIFNNKPKKAIPVLIKKGFLK
DDSPISIAKWLLETEGLDMAAVGDYLGEGDDKNIAIMHAFVDEFDFTGMSIVDALRSF
LQSFRLPGEGQKIDRFMLKFAERFVDQNPGVFSKADTAYVLSYSLIMLNTDLHSSQIK
NKMSLQEFLENNEGIDNGRDLPRDFLEGLFNEIANNEIKLISEQHQAMLSGDTNLVQQ
QQSAFNFFNSRDLTREAYNQVSKEISSKTELVFKNLNKNKGGPDVYYAASHVEHVKSI
FETLWMSFLAALTPPFKDYDDIDTTNKCLEGLKISIKIASTFRINDARTSFVGALVQF
CNLQNLEEIKVKNVNAMVILLEVALSEGNYLEGSWKDILLVVSQMERLQLISKGIDRD
TVPDVAQARVANPRVSYESSRSNNTSFFDVWGKKATPTELAQEKHHNQTLSPEISKFI
SSSELVVLMDNIFTKSSELSGNAIVDFIKALTAVSLEEIESSENASTPRMFSLQKMVD
VCYYNMDRIKLEWTPLWAVMGKAFNKIATNSNLAVVFFAIDSLRQLSMRFLDIEELSG
FEFQHDFLKPFEYTVQNSGNTEVQEMIIECFRNFILTKSESIKSGWKPILESLQYTAR
SSTESIVLKTQLLVSNDIVTNHFENVFSQEDAFSELVGVFREITKNKRFQKLSLHALE
SLRKMTQNVADICFYNENKTEEERKHNDALLRGKDIFQDVWFPMLFCFNDTIMTAEDL
EVRSRALNYMFDALVAYGGKFNDDFWEKICKKLLFPIFGVLSKHWEVNQFNSHDDLSV
WLSTTLIQALRNLIALFTHYFESLNRMLDGFLGLLVSCICQENDTIARIGRSCLQQLI
LQNVSKFNEYHWNQIGDVFDKLFDLTTANELFDYDPLQQGRKSSVSHHQTTNDTSQHS
DDDSNDRRENDSNISETVERAHQEESSEDVGGDMVETLNGQTKLNNGNSVPTVKDELN
PKPASLSIPKKTKHMKRNESNEDIRRRINIKNSIVVKCVLQLLMIELLNELFENEDFA
HCIPYKEAIRITRLLEKSYEFSRDFNEDYGLRTRLVEARVVDKIPNLLKQETSAAAVL
LDIMFQLYLNDDEKKADLITRLITICIQVVEGYVSLDDRTMERSINAWRSVIVEILQG
YYEFDDEDFRLYCPAMYALVIQILDKSVPTELRHAIKQFLSRVGELYLSTD"
gene complement(802731..802802)
/locus_tag="tQ(UUG)D3"
/db_xref="GeneID:851749"
tRNA complement(802731..802802)
/locus_tag="tQ(UUG)D3"
/product="tRNA-Gln"
/note="Glutamine tRNA (tRNA-Gln), predicted by tRNAscan-SE
analysis; thiolation of uridine at wobble position (34)
requires Ncs6p"
/db_xref="SGD:S000006695"
/db_xref="GeneID:851749"
LTR 802905..803235
/note="Ty1 LTR"
/db_xref="SGD:S000006865"
gene 803195..804517
/locus_tag="YDR170W-A"
/db_xref="GeneID:851750"
mRNA <803195..>804517
/locus_tag="YDR170W-A"
/transcript_id="NM_001184320.1"
/db_xref="GI:296143520"
/db_xref="GeneID:851750"
CDS 803195..804517
/locus_tag="YDR170W-A"
/note="Retrotransposon TYA Gag gene; Gag is a nucleocapsid
protein that is the structural constituent of virus-like
particles (VLPs); similar to retroviral Gag; YDR170W-A is
part of a mutant retrotransposon; distribution in the
cytoplasm becomes irregular rather than punctate upon DNA
replication stress"
/codon_start=1
/product="gag protein"
/protein_id="NP_010455.1"
/db_xref="GI:6320375"
/db_xref="SGD:S000007227"
/db_xref="GeneID:851750"
/translation="MESQQLSQHSPISHGSACASVTSKEVQTTQDPLDISASKTEECE
KVFTQANSQQPTTPPSAAVPENHHHASPQAAQVPLPQNGPYPQQRMMTPQQANISGWP
VYGHPSLMPYPPYQMSPMYAPPGAQSQFTQYPQYVGTHLNTPSPESGNSFPDSSSAKS
NMTSTNQHVRPPPILTSPNDFLNWVKIYIKFLQNSNLGDIIPTATRKAVRQMTDDELT
FLCHTFQLFALSQFLPTWVKDILSVDYTDIMKILSKSINKMQSDTQEVNDITTLANLH
YNGSTPADAFEAEVTNILDRLKNNGIPINNKVACQFIMRGLSGEYKFLRYARHRYIHM
TVADLFSDIHSMYEEQQESKRNKSTYRRSPSDEKKDSRTYTNTTKPKSITRNSQKPNN
SQSRTARAHNVSTSNNFPGPDNDLIRGSTTEPIQLKNKHDLHLRPGTY"
rep_origin 806052..806277
/note="ARS425;
Autonomously Replicating Sequence"
/db_xref="SGD:S000118439"
gene 806621..807748
/gene="HSP42"
/locus_tag="YDR171W"
/db_xref="GeneID:851751"
mRNA 806621..807748
/gene="HSP42"
/locus_tag="YDR171W"
/product="Hsp42p"
/transcript_id="NM_001180478.1"
/db_xref="GI:296143521"
/db_xref="GeneID:851751"
CDS 806621..807748
/gene="HSP42"
/locus_tag="YDR171W"
/note="Small heat shock protein (sHSP) with chaperone
activity; forms barrel-shaped oligomers that suppress
unfolded protein aggregation; involved in cytoskeleton
reorganization after heat shock; protein abundance
increases and forms cytoplasmic foci in response to DNA
replication stress"
/codon_start=1
/product="Hsp42p"
/protein_id="NP_010456.1"
/db_xref="GI:6320376"
/db_xref="SGD:S000002578"
/db_xref="GeneID:851751"
/translation="MSFYQPSLSLYDVLNALSNQTGQRGQQGYPRQPQRPQRYHPHYG
QVHVGGHHPRHHPLYSRYNGVPNTYYYQFPGQAYYYSPEYGYDDEDGEEEDQDEDMVG
DSGTTRQEDGGEDSNSRRYPSYYHCNTARNNRTNQQANSLNDLLTALIGVPPYEGTEP
EIEANTEQEGEKGEEKDKKDKSEAPKEEAGETNKEKPLNQLEESSRPPLAKKSSSFAH
LQAPSPIPDPLQVSKPETRMDLPFSPEVNVYDTEDTYVVVLALPGANSRAFHIDYHPS
SHEMLIKGKIEDRVGIDEKFLKITELKYGAFERTVKFPVLPRIKDEEIKATYNNGLLQ
IKVPKIVNDTEKPKPKKRIAIEEIPDEELEFEENPNPTVEN"
gene 808324..810381
/gene="SUP35"
/locus_tag="YDR172W"
/gene_synonym="GST1; PNM2; SAL3; SUF12; SUP2; SUP36"
/db_xref="GeneID:851752"
mRNA 808324..810381
/gene="SUP35"
/locus_tag="YDR172W"
/gene_synonym="GST1; PNM2; SAL3; SUF12; SUP2; SUP36"
/product="Sup35p"
/transcript_id="NM_001180479.3"
/db_xref="GI:398365952"
/db_xref="GeneID:851752"
CDS 808324..810381
/gene="SUP35"
/locus_tag="YDR172W"
/gene_synonym="GST1; PNM2; SAL3; SUF12; SUP2; SUP36"
/note="Translation termination factor eRF3, has a role in
mRNA deadenylation and decay; altered protein conformation
creates the [PSI(+)] prion that alters translational
fidelity and results in a nonsense suppressor phenotype"
/codon_start=1
/product="Sup35p"
/protein_id="NP_010457.3"
/db_xref="GI:398365953"
/db_xref="SGD:S000002579"
/db_xref="GeneID:851752"
/translation="MSDSNQGNNQQNYQQYSQNGNQQQGNNRYQGYQAYNAQAQPAGG
YYQNYQGYSGYQQGGYQQYNPDAGYQQQYNPQGGYQQYNPQGGYQQQFNPQGGRGNYK
NFNYNNNLQGYQAGFQPQSQGMSLNDFQKQQKQAAPKPKKTLKLVSSSGIKLANATKK
VGTKPAESDKKEEEKSAETKEPTKEPTKVEEPVKKEEKPVQTEEKTEEKSELPKVEDL
KISESTHNTNNANVTSADALIKEQEEEVDDEVVNDMFGGKDHVSLIFMGHVDAGKSTM
GGNLLYLTGSVDKRTIEKYEREAKDAGRQGWYLSWVMDTNKEERNDGKTIEVGKAYFE
TEKRRYTILDAPGHKMYVSEMIGGASQADVGVLVISARKGEYETGFERGGQTREHALL
AKTQGVNKMVVVVNKMDDPTVNWSKERYDQCVSNVSNFLRAIGYNIKTDVVFMPVSGY
SGANLKDHVDPKECPWYTGPTLLEYLDTMNHVDRHINAPFMLPIAAKMKDLGTIVEGK
IESGHIKKGQSTLLMPNKTAVEIQNIYNETENEVDMAMCGEQVKLRIKGVEEEDISPG
FVLTSPKNPIKSVTKFVAQIAIVELKSIIAAGFSCVMHVHTAIEEVHIVKLLHKLEKG
TNRKSKKPPAFAKKGMKVIAVLETEAPVCVETYQDYPQLGRFTLRDQGTTIAIGKIVK
IAE"
gene complement(810565..811632)
/gene="ARG82"
/locus_tag="YDR173C"
/gene_synonym="ARGR3; IPK2"
/db_xref="GeneID:851753"
mRNA complement(810565..811632)
/gene="ARG82"
/locus_tag="YDR173C"
/gene_synonym="ARGR3; IPK2"
/product="inositol polyphosphate multikinase"
/transcript_id="NM_001180480.3"
/db_xref="GI:398365956"
/db_xref="GeneID:851753"
CDS complement(810565..811632)
/gene="ARG82"
/locus_tag="YDR173C"
/gene_synonym="ARGR3; IPK2"
/EC_number="2.7.1.151"
/note="Inositol polyphosphate multikinase (IPMK),
sequentially phosphorylates Ins(1,4,5)P3 to form
Ins(1,3,4,5,6)P5; also has diphosphoinositol polyphosphate
synthase activity; regulates arginine-, phosphate-, and
nitrogen-responsive genes"
/codon_start=1
/product="inositol polyphosphate multikinase"
/protein_id="NP_010458.3"
/db_xref="GI:398365957"
/db_xref="SGD:S000002580"
/db_xref="GeneID:851753"
/translation="MDTVNNYRVLEHKAAGHDGTLTDGDGLLIFKPAFPQELEFYKAI
QVRDVSRRKSSADGDAPLCSWMPTYLGVLNEGAKIEQSGDAALLKIDERLSDSTDNLD
SIPVKSEKSKQYLVLENLLYGFSKPNILDIKLGKTLYDSKASLEKRERMKRVSETTTS
GSLGFRICGMKIQKNPSVLNQLSLEYYEEEADSDYIFINKLYGRSRTDQNVSDAIELY
FNNPHLSDARKHQLKKTFLKRLQLFYNTMLEEEVRMISSSLLFIYEGDPERWELLNDV
DKLMRDDFIDDDDDDDDNDDDDDDDAEGSSEGPKDKKTTGSLSSMSLIDFAHSEITPG
KGYDENVIEGVETLLDIFMKF"
gene 812110..812850
/gene="HMO1"
/locus_tag="YDR174W"
/gene_synonym="HSM2"
/db_xref="GeneID:851754"
mRNA 812110..812850
/gene="HMO1"
/locus_tag="YDR174W"
/gene_synonym="HSM2"
/product="Hmo1p"
/transcript_id="NM_001180481.1"
/db_xref="GI:296143524"
/db_xref="GeneID:851754"
CDS 812110..812850
/gene="HMO1"
/locus_tag="YDR174W"
/gene_synonym="HSM2"
/note="Chromatin associated high mobility group (HMG)
family member involved in genome maintenance; rDNA-binding
component of the Pol I transcription system; associates
with a 5'-3' DNA helicase and Fpr1p, a prolyl isomerase"
/codon_start=1
/product="Hmo1p"
/protein_id="NP_010459.1"
/db_xref="GI:6320379"
/db_xref="SGD:S000002581"
/db_xref="GeneID:851754"
/translation="MTTDPSVKLKSAKDSLVSSLFELSKAANQTASSIVDFYNAIGDD
EEEKIEAFTTLTESLQTLTSGVNHLHGISSELVNPIDDDKDAIIAAPVKAVRRKIERD
PNAPKKPLTVFFAYSAYVRQELREDRQKAGLPPLSSTEITQEISKKWKELSDNEKEKW
KQAYNVELENYQREKSKYLEAKKNGTLPPASLENGPTHAPVPIPFSLQHAAEPPVEKR
PHDDDGSSEKKKKKKKKDKKKDKSNSSI"
gene complement(813193..814152)
/gene="RSM24"
/locus_tag="YDR175C"
/db_xref="GeneID:851755"
mRNA complement(813193..814152)
/gene="RSM24"
/locus_tag="YDR175C"
/product="mitochondrial 37S ribosomal protein RSM24"
/transcript_id="NM_001180482.1"
/db_xref="GI:296143525"
/db_xref="GeneID:851755"
CDS complement(813193..814152)
/gene="RSM24"
/locus_tag="YDR175C"
/note="Mitochondrial ribosomal protein of the small
subunit"
/codon_start=1
/product="mitochondrial 37S ribosomal protein RSM24"
/protein_id="NP_010460.1"
/db_xref="GI:6320380"
/db_xref="SGD:S000002582"
/db_xref="GeneID:851755"
/translation="MKVPLGLWKVSRGNLWSTQKRVLTMSRCLNSDAGNEAKTVREGP
AFSADLYMHPEKWKGLPPQRILELYWERMARLGSEYKPNKDELNALLTTSEYSNVPVN
DIKKLYHRGEQGAIDIKGGNVNRDNSLRPFMFDELPSQAQELVAQHREQRFYNRLAAY
ELPLLAQYRQEYKRPSPESHPVTYRYTSYVGEEHPNSRKVVLSVKTKELGLEEKSLHK
FRILARSRYDHTTDIFKMSSDKFEHASQNARYLHDILQRLLAESKDLTEDDFSDVPLD
TRHTIAKSLRKKKRDYEFPEHWKRPEDAPKKKFDIVDQLLSTL"
gene 814452..816560
/gene="NGG1"
/locus_tag="YDR176W"
/gene_synonym="ADA3; SWI7"
/db_xref="GeneID:851756"
mRNA 814452..816560
/gene="NGG1"
/locus_tag="YDR176W"
/gene_synonym="ADA3; SWI7"
/product="Ngg1p"
/transcript_id="NM_001180483.3"
/db_xref="GI:398365962"
/db_xref="GeneID:851756"
CDS 814452..816560
/gene="NGG1"
/locus_tag="YDR176W"
/gene_synonym="ADA3; SWI7"
/note="Transcriptional regulator involved in glucose
repression of Gal4p-regulated genes; component of
transcriptional adaptor and histone acetyltransferase
complexes, the ADA complex, the SAGA complex, and the SLIK
complex"
/codon_start=1
/product="Ngg1p"
/protein_id="NP_010461.3"
/db_xref="GI:398365963"
/db_xref="SGD:S000002583"
/db_xref="GeneID:851756"
/translation="MPRHGRRGKLPKGEKLPKKEGGDNTPSKLLSSMLKTLDLTFERD
IGMLNGKSVRSIPNKKTLLELQSQLDSLNEILGTIARGDQETIEALRKIRDSKNEKQA
NDEKQETSNADGQHESSTATEETNIIDKGVQSPPKPPPSNEISGTIENDVESIKQAAD
NMAKEEINEDKDLQVHRDQPREKRPFDSETENRATENENTQRPDNKKQKIDVDKMEND
PTVKNPKSEFVVSQTLPRAAAALGLFNEEGLESTGEDFLKKKYNVASYPTNDLKDLLP
GELPDMDFSHPKPTNQIQFNTFLAFVENFFKDLSDDNLKFLKMKYIIPDSLQFDKTYD
PEVNPFIIPKLGPLYTDVWFKDENDKNSAYKKPSPYSNDASTILPKKSANELDDNALE
SGSISCGPLLSRLLSAVLKDDNDKSELQSSKIIRDGGLPRTGGEDDIQSFRNNNNDTV
DMTLSQENGPSVQTPDNDIDEEASFQAKLAENKGSNGGTTSTLPQQIGWITNGINLDY
PTFEERLKRELKYVGIYMNLPKDENNPNSDDPDWVTGREDDEISAELRELQGTLKQVT
KKNQKRKAQLIPLVERQLAWQEYSSILEDLDKQIDQAYVKRIRVPKKRKKHHTAASNN
VNTGTTSQIAQQKAANSSLKSLLDKRQRWINKIGPLFDKPEIMKRIPNESVFKDMDQE
EDEDEADVFAQNTNKDVELN"
gene 816878..817525
/gene="UBC1"
/locus_tag="YDR177W"
/db_xref="GeneID:851757"
mRNA 816878..817525
/gene="UBC1"
/locus_tag="YDR177W"
/product="E2 ubiquitin-conjugating protein UBC1"
/transcript_id="NM_001180484.3"
/db_xref="GI:398365964"
/db_xref="GeneID:851757"
CDS 816878..817525
/gene="UBC1"
/locus_tag="YDR177W"
/EC_number="6.3.2.19"
/note="Ubiquitin-conjugating enzyme; mediates selective
degradation of short-lived and abnormal proteins; plays a
role in vesicle biogenesis and ER-associated protein
degradation (ERAD); component of the cellular stress
response; protein abundance increases in response to DNA
replication stress"
/codon_start=1
/product="E2 ubiquitin-conjugating protein UBC1"
/protein_id="NP_010462.3"
/db_xref="GI:398365965"
/db_xref="SGD:S000002584"
/db_xref="GeneID:851757"
/translation="MSRAKRIMKEIQAVKDDPAAHITLEFVSESDIHHLKGTFLGPPG
TPYEGGKFVVDIEVPMEYPFKPPKMQFDTKVYHPNISSVTGAICLDILKNAWSPVITL
KSALISLQALLQSPEPNDPQDAEVAQHYLRDRESFNKTAALWTRLYASETSNGQKGNV
EESDLYGIDHDLIDEFESQGFEKDKIVEVLRRLGVKSLDPNDNNTANRIIEELLK"
gene 817950..818495
/gene="SDH4"
/locus_tag="YDR178W"
/gene_synonym="ACN18"
/db_xref="GeneID:851758"
mRNA 817950..818495
/gene="SDH4"
/locus_tag="YDR178W"
/gene_synonym="ACN18"
/product="succinate dehydrogenase membrane anchor subunit
SDH4"
/transcript_id="NM_001180485.1"
/db_xref="GI:296143528"
/db_xref="GeneID:851758"
CDS 817950..818495
/gene="SDH4"
/locus_tag="YDR178W"
/gene_synonym="ACN18"
/EC_number="1.3.5.1"
/note="Membrane anchor subunit of succinate dehydrogenase
(Sdh1p, Sdh2p, Sdh3p, Sdh4p), which couples the oxidation
of succinate to the transfer of electrons to ubiquinone as
part of the TCA cycle and the mitochondrial respiratory
chain"
/codon_start=1
/product="succinate dehydrogenase membrane anchor subunit
SDH4"
/protein_id="NP_010463.1"
/db_xref="GI:6320383"
/db_xref="SGD:S000002585"
/db_xref="GeneID:851758"
/translation="MMLPRSMKFMTGRRIFHTATVRAFQSTAKKSLTIPFLPVLPQKP
GGVRGTPNDAYVPPPENKLEGSYHWYMEKIFALSVVPLATTAMLTTGPLSTAADSFFS
VMLLGYCYMEFNSCITDYISERVYGVWHKYAMYMLGLGSAVSLFGIYKLETENDGVVG
LVKSLWDSSEKDNSQKIEAKK"
gene complement(818708..819196)
/gene="CSN9"
/locus_tag="YDR179C"
/db_xref="GeneID:851759"
mRNA complement(818708..819196)
/gene="CSN9"
/locus_tag="YDR179C"
/product="Csn9p"
/transcript_id="NM_001180486.1"
/db_xref="GI:296143529"
/db_xref="GeneID:851759"
CDS complement(818708..819196)
/gene="CSN9"
/locus_tag="YDR179C"
/note="Subunit of the Cop9 signalosome, which is required
for deneddylation, or removal of the ubiquitin-like
protein Rub1p from Cdc53p (cullin); involved in adaptation
to pheromone signaling"
/codon_start=1
/product="Csn9p"
/protein_id="NP_010464.1"
/db_xref="GI:6320384"
/db_xref="SGD:S000002586"
/db_xref="GeneID:851759"
/translation="MVMREETIKSLEDPYKYHYKEEWLNTKDPDEQQLFEIFAFGNIK
DLPENIILTSLMRSKLEKLTLVTLSEIYNELSYELIKEECQIEDDGIIESHLIQLQNI
FKAEMDSVSKSMKFSRRFDCRDVYCHEKELTIIKNPRVTKEYLVQNLRSWETKLKQNI
LE"
gene 819433..820824
/locus_tag="YDR179W-A"
/db_xref="GeneID:851760"
mRNA 819433..820824
/locus_tag="YDR179W-A"
/product="hypothetical protein"
/transcript_id="NM_001180487.3"
/db_xref="GI:398365980"
/db_xref="GeneID:851760"
CDS 819433..820824
/locus_tag="YDR179W-A"
/codon_start=1
/product="hypothetical protein"
/protein_id="NP_010465.4"
/db_xref="GI:398365981"
/db_xref="SGD:S000002587"
/db_xref="GeneID:851760"
/translation="MPTILYNTNSSLITKYRRPNASNQYKGFLSKKGHTRLNSKSSGD
IWEKDCSHTKNSGNDVSFESEFEKDSVEYLRDLCFSIYPNSLHQKIRSIEALPDLQVN
TFIALIFQNFVKSWYGIKIPTDDSKFLTELYNLVQDLITYLKSSKINYHALLLDYIPC
LLSSHLKALNDSSQNNDLVYEQYCKLTLYDSKRYPMLFTEIIQSKMSTKSLLQRSFLD
SFLNELVFGHIFNSIAEPYYLLEGLNKICIRIKLNSAGNTRNEVTHGKPKCDPWLFVS
NVKHKILQMTRLLAYSTSTEAANMNTAEIQETAFLQRYIFTFFTDDFFKLSMRKPFLF
SICRTLQHWISKLNALNRVMYRTFDNIVQTKITSPVTIGNLFSLLRHSLFPNDNMMGP
PRVLPVGDAFLEFREECISNLWDVCMTYKLDHILAIKRSDIADLIICISKNRDCNKLL
IYRIIDCVIAQLP"
gene 821295..825776
/gene="SCC2"
/locus_tag="YDR180W"
/db_xref="GeneID:851761"
mRNA 821295..825776
/gene="SCC2"
/locus_tag="YDR180W"
/product="Scc2p"
/transcript_id="NM_001180488.3"
/db_xref="GI:398365986"
/db_xref="GeneID:851761"
CDS 821295..825776
/gene="SCC2"
/locus_tag="YDR180W"
/note="Subunit of cohesin loading factor (Scc2p-Scc4p), a
complex required for loading of cohesin complexes onto
chromosomes; involved in establishing sister chromatid
cohesion during DSB repair via histone H2AX;
evolutionarily-conserved adherin"
/codon_start=1
/product="Scc2p"
/protein_id="NP_010466.3"
/db_xref="GI:398365987"
/db_xref="SGD:S000002588"
/db_xref="GeneID:851761"
/translation="MSYPGKDKNIPGRIIEALEDLPLSYLVPKDGLAALVNAPMRVSL
PFDKTIFTSADDGRDVNINVLGTANSTTSSIKNEAEKERLVFKRPSNFTSSANSVDYV
PTNFLEGLSPLAQSVLSTHKGLNDSINIEKKSEIVSRPEAKHKLESVTSNAGNLSFND
NSSNKKTKTSTGVTMTQANLAEQYLNDLKNILDIVGFDQNSAEIGNIEYWLQLPNKKF
VLTTNCLTKLQMTIKNITDNPQLSNSIEITWLLRLLDVMVCNIKFSKSSLKMGLDDSM
LRYIALLSTIVLFNIFLLGKNDSNLHRESYIMEPVNFLSDLIESLKILTIEYGSLKIE
FDTFQEALELLPKYIRNGPFLDDNVTAKLVYIFSDLLMNNDIEATTNIQFQSFWDNVK
RISSDILVSLFGSFDQQRGFIIEELLSHIEKLPTKRIQKKLRKVGNQNIYITDFTFTL
MSMLENINCYSFCNQMKDIAPENIDLLKNEYKKQEEFLFNIVEHINDTILERFFKNPS
ALRYVIDNFVQDLLLLISSPQWPVTEKILSSLLKRLLSVYSPSMQVSANIETICLQLI
GNIGSTIFDIKCSTRDHEDNNLIKMINYPETLPHFFKSFEECIAYNETIKCRRSATRF
LWNLRLGTILILEEYTKDAKEQIITVDNELKKILEQIKDGGLGPELENREADFSTIKL
DYFSILHAFELLNLYDPYLKLILSLLAKDKIKLRSTAIKCLSMLASKDKVILSNPMVK
ETIHRRLNDSSASVKDAILDLVSINSSYFEFYQQINNNYNDDSIMVRKHVLRINEKMY
DETNDIVTKVYVIARILMKIEDEEDNIIDMARLILLNRWILKVHEVLDQPEKLKEISS
SVLLVMSRVAIMNEKCSQLFDLFLNFYLLNKEAHSKEAYDKITHVLTILTDFLVQKIV
ELNSDDTNEKNSIVDKQNFLNLLAKFADSTVSFLTKDHITALYPYMVSDEKSDFHYYI
LQVFRCTFEKLANFKQKFLYDLETTLLSRLPKMNVREIDEAMPLIWSVATHRHDTARV
AKACSSCLSHLHPYINKANNEEAAIVVDGKLQRLIYLSTGFARFCFPKPSNDKIAFLQ
EGETLYEHITKCLLVLSKDKITHVIRRVAVKNLTKLCGNHPKLFNSRHVLHLLDKEFQ
SDQLDIKLVILESLYDLFLLEERKSVRNTGVNSTLSSNSILKKKLLKTNRVEFANDGV
CSALATRFLDNILQLCLLRDLKNSLVAIRLLKLILKFGYTNPSHSIPTVIALFASTSQ
YIRHVAYELLEDLFEKYETLVFSSLSRGVTKAIHYSIHTDEKYYYKHDHFLSLLEKLC
GTGKKNGPKFFKVLKRIMQSYLDDITDLTSTNSSVQKSIFVLCTNISNITFVSQYDLV
SLLKTIDLTTDRLKEVIMDEIGDNVSSLSVSEEKLSGIILIQLSLQDLGTYLLHLYGL
RDDVLLLDIVEESELKNKQLPAKKPDISKFSAQLENIEQYSSNGKLLTYFRKHVKDT"
gene complement(825910..827355)
/gene="SAS4"
/locus_tag="YDR181C"
/db_xref="GeneID:851762"
mRNA complement(825910..827355)
/gene="SAS4"
/locus_tag="YDR181C"
/product="Sas4p"
/transcript_id="NM_001180489.1"
/db_xref="GI:296143532"
/db_xref="GeneID:851762"
CDS complement(825910..827355)
/gene="SAS4"
/locus_tag="YDR181C"
/note="Subunit of the SAS complex (Sas2p, Sas4p, Sas5p),
which acetylates free histones and nucleosomes and
regulates transcriptional silencing; required for the HAT
activity of Sas2p"
/codon_start=1
/product="Sas4p"
/protein_id="NP_010467.1"
/db_xref="GI:6320387"
/db_xref="SGD:S000002589"
/db_xref="GeneID:851762"
/translation="MGIFQSIEEANNTSERLLRSEIKNSHGEFEKFDFDTEEYEINPK
RKLRLVSRINPNAGHLRKSKSCFTVDEHVDETRCQKPVMKSPFMSNVDDEIKKKRETI
TKMTLEIEHHELSQNIRKPTDDLLPDSTYQPYHKKMLKQENRMIQSDIVNGENEADRL
SLISDRLGMLNWEVTLQKVTKINDPTDENEMETKRYQTKELIDSMLHKFESMKKKSRN
LARRPASSDSLLKLVSGKDWPKIYTRIDRTFIPDYASSSDEEEEKITVEEIRERRLKK
REQQCGGSIIVLLSDHQSQKGMTRFAIVAEPLRKPYLIKTSTKERNSWKNKVPTNPKK
FKKAPRISTQIAVKRRREVIPLTMEVEPEVIRDIRQDTQKSMKLNVKAEEISVTETVK
SKEMNALRNNAASISPTLSEKAPLGSISSCTASQISQRSSENVGAIINNINPNLAIVP
SCNEKTFVKTHNGMKTNSGINILPVRKKKKV"
gene 827582..829057
/gene="CDC1"
/locus_tag="YDR182W"
/gene_synonym="DSC1; DSR1; ESP2"
/db_xref="GeneID:851763"
mRNA 827582..829057
/gene="CDC1"
/locus_tag="YDR182W"
/gene_synonym="DSC1; DSR1; ESP2"
/product="putative lipid phosphatase CDC1"
/transcript_id="NM_001180490.1"
/db_xref="GI:296143533"
/db_xref="GeneID:851763"
CDS 827582..829057
/gene="CDC1"
/locus_tag="YDR182W"
/gene_synonym="DSC1; DSR1; ESP2"
/note="Putative lipid phosphatase of the endoplasmic
reticulum; shows Mn2+ dependence and may affect Ca2+
signaling; mutants display actin and general growth
defects and pleiotropic defects in cell cycle progression
and organelle distribution"
/codon_start=1
/product="putative lipid phosphatase CDC1"
/protein_id="NP_010468.1"
/db_xref="GI:6320388"
/db_xref="SGD:S000002590"
/db_xref="GeneID:851763"
/translation="MVYRNRSKSVLSTHSKKSDDKAHYKSRSKKKSKSRSKKRLRIYW
RYISIVWILWLGLISYYESVVVKRAMKKCQWSTWEDWPEGAESHRVGLFADPQIMDEY
SYPGRPQIVNYFTRVIVDHYHRRNWKYVQYYLDPDSNFFLGDLFDGGRNWDDKQWIKE
YTRFNQIFPKKPLRRTVMSLPGNHDIGFGDTVVESSLQRFSSYFGETSSSLDAGNHTF
VLLDTISLSDKTNPNVSRVPRQFLDNFAMGSHPLPRILLTHVPLWRDPEQQTCGQLRE
SKEPFPIQKGHQYQTVIENDISQEILTKIQPEILFSGDDHDHCQISHSYPFQGKTKNA
QEITVKSCAMNMGISRPAIQLLSLYNPSDLTMVNAGGEYASKTYQTELCYMPDPYKAI
RMYLWGLLFSAAFIAYMHFFPKSFNNRVATIMNRVFTRPDGNTSDLPLPTSISKSKSK
KSLTHSKYAVNDTRSIKQFLVNAIVLFVSVMPIFIYFYTVV"
gene 829151..829354
/locus_tag="YDR182W-A"
/db_xref="GeneID:1466434"
mRNA 829151..829354
/locus_tag="YDR182W-A"
/product="hypothetical protein"
/transcript_id="NM_001184545.3"
/db_xref="GI:398365992"
/db_xref="GeneID:1466434"
CDS 829151..829354
/locus_tag="YDR182W-A"
/note="hypothetical protein; identified by fungal homology
and RT-PCR"
/codon_start=1
/product="hypothetical protein"
/protein_id="NP_878063.3"
/db_xref="GI:398365993"
/db_xref="SGD:S000028539"
/db_xref="GeneID:1466434"
/translation="MNKRYKLYRVWYYYAHQTVCITSTGFALCFVVQAKTAGLGVTPI
TSLYGDKKEHLGKLLVPLVLYQI"
gene 829585..830277
/gene="PLP1"
/locus_tag="YDR183W"
/db_xref="GeneID:851764"
mRNA 829585..830277
/gene="PLP1"
/locus_tag="YDR183W"
/product="Plp1p"
/transcript_id="NM_001180491.3"
/db_xref="GI:398366004"
/db_xref="GeneID:851764"
CDS 829585..830277
/gene="PLP1"
/locus_tag="YDR183W"
/note="Protein that interacts with CCT (chaperonin
containing TCP-1) complex and has a role in actin and
tubulin folding; has weak similarity to phosducins, which
are G-protein regulators"
/codon_start=1
/product="Plp1p"
/protein_id="NP_010469.3"
/db_xref="GI:398366005"
/db_xref="SGD:S000002591"
/db_xref="GeneID:851764"
/translation="MEDKLDRYYTNVLSNAEKDKHTTVDSDDKSSGEENLDELLNELD
RELDEDHEFLSAYRSERLQQISDHLKQVKKNVEDDGYGRLQCIDNEADAIQICTKTTM
VVIHFELETFGKCQYMNEKLENLAKRYLTTRFIKVNVQTCPFLVNKLNIKVLPFVVGY
KNGLEKVRYVGFSKLGNDPNGFDIRRLEQSLAHSGVIEDTFEIRKHSSVNTERFASTN
HDRSESDSDLDI"
gene complement(830629..831513)
/gene="ATC1"
/locus_tag="YDR184C"
/gene_synonym="LIC4"
/db_xref="GeneID:851765"
mRNA complement(830629..831513)
/gene="ATC1"
/locus_tag="YDR184C"
/gene_synonym="LIC4"
/product="Atc1p"
/transcript_id="NM_001180492.1"
/db_xref="GI:296143536"
/db_xref="GeneID:851765"
CDS complement(830629..831513)
/gene="ATC1"
/locus_tag="YDR184C"
/gene_synonym="LIC4"
/note="Nuclear protein; possibly involved in regulation of
cation stress responses and/or in the establishment of
bipolar budding pattern; relative distribution to the
nucleus decreases upon DNA replication stress"
/codon_start=1
/product="Atc1p"
/protein_id="NP_010470.1"
/db_xref="GI:6320390"
/db_xref="SGD:S000002592"
/db_xref="GeneID:851765"
/translation="MNTNQSNPNTDLTDDANIEHTLHRLLTQANNHFDDTVKIDGQSL
DLGKDLEQVMMDNLDCTDIFDSDIASQKHLTLESLFNDEHNTDSSTLLEMQRSANDSL
VGIDLDRHKKGYTGKASLDKSTNQNNVHKPDKEQKNYKIDKPTIKKKKSLLKTTNEPM
LSPASLSPSSSLASSDANESHLKIESMITDITSKIDSARQDIVSATKPAKFTNEFTIS
QISEMKARIINTHKLLLNFNFIKEGYARSCIQLKKSMDSLKDSEIHRAHLLVENDDLK
QQILELTQKLNEKSSKES"
gene complement(831934..832473)
/gene="UPS3"
/locus_tag="YDR185C"
/gene_synonym="GEP2"
/db_xref="GeneID:851766"
mRNA complement(831934..832473)
/gene="UPS3"
/locus_tag="YDR185C"
/gene_synonym="GEP2"
/product="Ups3p"
/transcript_id="NM_001180493.1"
/db_xref="GI:296143537"
/db_xref="GeneID:851766"
CDS complement(831934..832473)
/gene="UPS3"
/locus_tag="YDR185C"
/gene_synonym="GEP2"
/note="Mitochondrial hypothetical protein; similar to
Ups1p and Ups2p which are involved in regulation of
mitochondrial cardiolipin and phosphatidylethanolamine
levels; null is viable but interacts synthetically with
ups1 and ups2 mutations"
/codon_start=1
/product="Ups3p"
/protein_id="NP_010471.1"
/db_xref="GI:6320391"
/db_xref="SGD:S000002593"
/db_xref="GeneID:851766"
/translation="MKSFQKSYEFDYPWEKVTTANWMKYPNKISTHVIAVDVLRRELK
EHGDVLLTERLITIRQNTPHWMSILVGNTNLAYVREVSTVDRRDRSLTMRSCNMTFPH
ILKCYETVRYVPHPKNPSNVTLFKQDAKFLSGVPTKTFSEKVENWGVKRFSDNAVKGK
VGFDSILAMFNDIWKNANE"
gene complement(832859..835492)
/locus_tag="YDR186C"
/db_xref="GeneID:851767"
mRNA complement(832859..835492)
/locus_tag="YDR186C"
/product="hypothetical protein"
/transcript_id="NM_001180494.3"
/db_xref="GI:398366012"
/db_xref="GeneID:851767"
CDS complement(832859..835492)
/locus_tag="YDR186C"
/note="hypothetical protein; may interact with ribosomes,
based on co-purification experiments; green fluorescent
protein (GFP)-fusion protein localizes to the cytoplasm"
/codon_start=1
/product="hypothetical protein"
/protein_id="NP_010472.3"
/db_xref="GI:398366013"
/db_xref="SGD:S000002594"
/db_xref="GeneID:851767"
/translation="MDTVGTDAAAASINERRFAQSTSPKVSVKSQDSLFLITYSNMQQ
TVVQASLADRYPSLKKLNILLYIDIPTIDYYNDEMTHNKLSRLNKRFKLHRLRNSIAQ
SFSNTSTAEDNDKFWEELKSLISSRSTPENKFDLNVLVSSSGSLRYVETIRFLVEKLF
NSFKDLYVQKKLNLCFQINVSPTSLKWFSTFLNAELLNLKIINWQNIGSFTKTIQNSK
SLPFKEYYTKLNEKFTGSNQSNGSMQDQTVLDSIVIVTNSTGVKALLTLLSDHPLTSL
ISQESIKALHEYSDAVNEDKGDDQSNTSLKRNSSSLLNFQNSVLTSNKDKSVRIRSLS
INRKSNRAHMFKTNESITTIPSTSINNLIGQESNLRKQPSGTALHLQSHLHPHSRSQS
YSSSNMSRSPSPFPYGKTPSNDELVYDELNNQINEVQDRAKNEEIVLYNNNNYDDYTK
ERGEQEQDRTSYADEYGFNYDDEEGGNEDNYDDDEDDDDDDDDDDESDDEGLSFYAPS
ILSRSGSSTDVLSSGIDSMAKNSKETRGRFRSLSLMDPALQKPFNQKFPNSQQPDSAG
ASSPKRSTSSNHFTNVYVHDGDFDGTDTINNKKNLSSATLIKRKSLMNRNLAPSISNG
LIPPEFISRISTPSTSASSSNSSLNDMSTVSNAFSKLLNDTSKKQKFLNSPIPQHTQQ
ASPLLMRNNSNSNLLFEKNLINKSFEELRRQPSVNLFSTLMNGNMEKNGLALNFKSRT
PTDALMANSIKNSNNSSHRLLNLEEEDQIMSGSLPKEREDDNDSTNSTIVPNHPDNDN
YNDNDNDNNTGINSNNFNLNLYDDNDSAGFTDVTTEGVKYSNSNSTVTKPVYKKAVTL
DLYGEDDMDNMGGWVLGGNAR"
gene 836421..838061
/gene="CCT6"
/locus_tag="YDR188W"
/gene_synonym="HTR3; TCP20; TCP6"
/db_xref="GeneID:851768"
mRNA 836421..838061
/gene="CCT6"
/locus_tag="YDR188W"
/gene_synonym="HTR3; TCP20; TCP6"
/product="Cct6p"
/transcript_id="NM_001180496.3"
/db_xref="GI:398366020"
/db_xref="GeneID:851768"
CDS 836421..838061
/gene="CCT6"
/locus_tag="YDR188W"
/gene_synonym="HTR3; TCP20; TCP6"
/note="Subunit of the cytosolic chaperonin Cct ring
complex, related to Tcp1p, essential protein that is
required for the assembly of actin and tubulins in vivo;
contains an ATP-binding motif"
/codon_start=1
/product="Cct6p"
/protein_id="NP_010474.3"
/db_xref="GI:398366021"
/db_xref="SGD:S000002596"
/db_xref="GeneID:851768"
/translation="MSLQLLNPKAESLRRDAALKVNVTSAEGLQSVLETNLGPKGTLK
MLVDGAGNIKLTKDGKVLLTEMQIQSPTAVLIARAAAAQDEITGDGTTTVVCLVGELL
RQAHRFIQEGVHPRIITDGFEIARKESMKFLDEFKISKTNLSNDREFLLQVARSSLLT
KVDADLTEVLTPIVTDAVLSVYDAQADNLDLHMVEIMQMQHLSPKDTTFIKGLVLDHG
GRHPDMPTRVKNAYVLILNVSLEYEKTEVNSGFFYSSADQRDKLAASERKFVDAKLKK
IIDLKNEVCGMDPDKGFVIINQKGIDPMSLDVFAKHNILALRRAKRRNMERLQLVTGG
EAQNSVEDLSPQILGFSGLVYQETIGEEKFTYVTENTDPKSCTILIKGSTHYALAQTK
DAVRDGLRAVANVLKDKNIIPGAGAFYIALSRYLRSANMNKLGAKGKTKTGIEAFAEA
LLVIPKTLVKNSGFDPLDVLAMVEDELDDAQDSDETRYVGVDLNIGDSCDPTIEGIWD
SYRVLRNAITGATGIASNLLLCDELLRAGRSTLKETPQ"
gene 838392..840392
/gene="SLY1"
/locus_tag="YDR189W"
/db_xref="GeneID:851770"
mRNA 838392..840392
/gene="SLY1"
/locus_tag="YDR189W"
/product="Sly1p"
/transcript_id="NM_001180497.1"
/db_xref="GI:296143540"
/db_xref="GeneID:851770"
CDS 838392..840392
/gene="SLY1"
/locus_tag="YDR189W"
/note="Hydrophilic protein involved in vesicle trafficking
between the ER and Golgi; SM (Sec1/Munc-18) family protein
that binds the tSNARE Sed5p and stimulates its assembly
into a trans-SNARE membrane-protein complex"
/codon_start=1
/product="Sly1p"
/protein_id="NP_010475.1"
/db_xref="GI:6320395"
/db_xref="SGD:S000002597"
/db_xref="GeneID:851770"
/translation="MAVEEIASRKDISLRDMQISAILKMLFLNKDLNNNDNITTITDD
IFNQQEIIWKVLILDIKSTATISSVLRVNDLLKAGITVHSLIKQDRSPLPDVPAIYFV
SPTKENIDIIVNDLKSDKYSEFYINFTSSLPRNLLEDLAQQVSITGKSDKIKQVYDQY
LDFIVTEPELFSLEISNAYLTLNDPKTTEEEITGLCANIADGLFNTVLTINSIPIIRA
AKGGPAEIIAEKLGTKLRDFVINTNSSSTSTLQGNDSLERGVLIILDRNIDFASMFSH
SWIYQCMVFDIFKLSRNTVTIPLESKENGTDNTTAKPLATKKYDIEPNDFFWMENSHL
PFPEAAENVEAALNTYKEEAAEITRKTGVTNISDLDPNSNNDTVQIQEVVKKLPELTA
KKNTIDTHMNIFAALLSQLESKSLDTFFEVEQDPGSTKTRSRFLDILKDGKTNNLEDK
LRSFIVLYLTSTTGLPKDFVQNVENYFKENDYDINALKYVYKLREFMQLSNMSLQNKS
LEDGSDSAFKPSNLTLSGIYGLTEGKLQGGVGSLISGIKKLLPEKKTIPITNVVDAIM
DPLNSSQKNLETTDSYLYIDPKITRGSHTRKPKRQSYNKSLVFVVGGGNYLEYQNLQE
WAHSQLHNPKKVMYGSTAITTPAEFLNEISRLGASNSSNNDA"
gene complement(840604..841995)
/gene="RVB1"
/locus_tag="YDR190C"
/gene_synonym="TIH1; TIP49; TIP49A"
/db_xref="GeneID:851771"
mRNA complement(840604..841995)
/gene="RVB1"
/locus_tag="YDR190C"
/gene_synonym="TIH1; TIP49; TIP49A"
/product="RuvB family ATP-dependent DNA helicase pontin"
/transcript_id="NM_001180498.1"
/db_xref="GI:296143541"
/db_xref="GeneID:851771"
CDS complement(840604..841995)
/gene="RVB1"
/locus_tag="YDR190C"
/gene_synonym="TIH1; TIP49; TIP49A"
/EC_number="3.6.1.-"
/note="ATP-dependent DNA helicase, also known as pontin;
member of the AAA+ and RuvB-like protein families; similar
to Rvb2p; conserved component of multiple complexes
including the INO80 complex, the Swr1 complex, and the
R2TP complex (Rvb1-Rvb2-Tah1-Pih1); involved in multiple
processes such as chromatin remodeling, box C/D snoRNP
assembly, and RNA polymerase II assembly"
/codon_start=1
/product="RuvB family ATP-dependent DNA helicase pontin"
/protein_id="NP_010476.1"
/db_xref="GI:6320396"
/db_xref="SGD:S000002598"
/db_xref="GeneID:851771"
/translation="MVAISEVKENPGVNSSNSGAVTRTAAHTHIKGLGLDESGVAKRV
EGGFVGQIEAREACGVIVDLIKAKKMSGRAILLAGGPSTGKTALALAISQELGPKVPF
CPLVGSELYSVEVKKTETLMENFRRAIGLRIKETKEVYEGEVTELTPEDAENPLGGYG
KTISHVIVGLKSAKGTKTLRLDPTIYESIQREKVSIGDVIYIEANTGAVKRVGRSDAY
ATEFDLETEEYVPLPKGEVHKKKEIVQDVTLHDLDVANARPQGGQDVISMMGQLLKPK
KTEITEKLRQEVNKVVAKYIDQGVAELIPGVLFIDEVNMLDIEIFTYLNKALESNIAP
VVVLASNRGMTTVRGTEDVISPHGVPPDLIDRLLIVRTLPYDKDEIRTIIERRATVER
LQVESSALDLLATMGTETSLRYALQLLAPCGILAQTSNRKEIVVNDVNEAKLLFLDAK
RSTKILETSANYL"
gene 842337..843449
/gene="HST4"
/locus_tag="YDR191W"
/db_xref="GeneID:851772"
mRNA 842337..843449
/gene="HST4"
/locus_tag="YDR191W"
/product="Hst4p"
/transcript_id="NM_001180499.3"
/db_xref="GI:398366028"
/db_xref="GeneID:851772"
CDS 842337..843449
/gene="HST4"
/locus_tag="YDR191W"
/EC_number="3.5.1.-"
/note="Member of the Sir2 family of NAD(+)-dependent
protein deacetylases; involved along with Hst3p in
silencing at telomeres, cell cycle progression, radiation
resistance, genomic stability and short-chain fatty acid
metabolism"
/codon_start=1
/product="Hst4p"
/protein_id="NP_010477.3"
/db_xref="GI:398366029"
/db_xref="SGD:S000002599"
/db_xref="GeneID:851772"
/translation="MKQKFVLPITPPSTAEKKPQTENRCNENLKPRRLLPQLKKSVRN
RKPRLSYRPELNSVFDLDAYVDSTHLSKSQRHHMDRDAGFISYALNYSKRMVVVSGAG
ISVAAGIPDFRSSEGIFSTVNGGSGKDLFDYNRVYGDESMSLKFNQLMVSLFRLSKNC
QPTKFHEMLNEFARDGRLLRLYTQNIDGLDTQLPHLSTNVPLAKPIPSTVQLHGSIKH
MECNKCLNIKPFDPELFKCDDKFDSRTEIIPSCPQCEEYETVRKMAGLRSTGVGKLRP
RVILYNEVHPEGDFIGEIANNDLKKRIDCLIIVGTSLKIPGVKNICRQFAAKVHANRG
IVLYLNTSMPPKNVLDSLKFVDLVVLGDCQHVTSLL"
gene complement(843569..844861)
/gene="NUP42"
/locus_tag="YDR192C"
/gene_synonym="RIP1; UIP1"
/db_xref="GeneID:851774"
mRNA complement(843569..844861)
/gene="NUP42"
/locus_tag="YDR192C"
/gene_synonym="RIP1; UIP1"
/product="Nup42p"
/transcript_id="NM_001180500.3"
/db_xref="GI:398366036"
/db_xref="GeneID:851774"
CDS complement(843569..844861)
/gene="NUP42"
/locus_tag="YDR192C"
/gene_synonym="RIP1; UIP1"
/note="FG-nucleoporin component of central core of the
nuclear pore complex (NPC); also part of the NPC
cytoplasmic filaments; contributes directly to
nucleocytoplasmic transport and maintenance of the NPC
permeability barrier and is involved in gene tethering at
the nuclear periphery; interacts with Gle1p"
/codon_start=1
/product="Nup42p"
/protein_id="NP_010478.3"
/db_xref="GI:398366037"
/db_xref="SGD:S000002600"
/db_xref="GeneID:851774"
/translation="MSAFGNPFTSGAKPNLSNTSGINPFTNNAASTNNMGGSAFGRPS
FGTANTMTGGTTTSAFGMPQFGTNTGNTGNTSISAFGNTSNAAKPSAFGAPAFGSSAP
INVNPPSTTSAFGAPSFGSTGFGAMAATSNPFGKSPGSMGSAFGQPAFGANKTAIPSS
SVSNSNNSAFGAASNTPLTTTSPFGSLQQNASQNASSTSSAFGKPTFGAATNTQSPFG
TIQNTSTSSGTGVSPFGTFGTNSNNKSPFSNLQSGAGAGSSPFGTTTSKANNNNNVGS
SAFGTTNNQSPFSGGSGGTFGSASNLNKNTNGNFQSSFGNKGFSFGITPQNDANKVSQ
SNPSFGQTMPNTDPNISLKSNGNATSFGFGQQQMNATNVNANTATGKIRFVQGLSSEK
DGILELADLAEETLKIFRANKFELGLVPDIPPPPALVA"
gene complement(845952..847946)
/gene="MSS116"
/locus_tag="YDR194C"
/db_xref="GeneID:851775"
mRNA complement(845952..847946)
/gene="MSS116"
/locus_tag="YDR194C"
/product="Mss116p"
/transcript_id="NM_001180502.1"
/db_xref="GI:296143544"
/db_xref="GeneID:851775"
CDS complement(845952..847946)
/gene="MSS116"
/locus_tag="YDR194C"
/EC_number="3.6.1.-"
/note="DEAD-box protein required for efficient splicing of
mitochondrial Group I and II introns; non-polar RNA
helicase that also facilities strand annealing"
/codon_start=1
/product="Mss116p"
/protein_id="NP_010480.1"
/db_xref="GI:6320400"
/db_xref="SGD:S000002602"
/db_xref="GeneID:851775"
/translation="MLTSILIKGRTPVLASRNLLAALSNCNHITWAVSRRLYNDGNRD
QRNFGRNQRNNNSNRYRNSRFNSRPRTRSREDDDEVHFDKTTFSKLIHVPKEDNSKEV
TLDSLLEEGVLDKEIHKAITRMEFPGLTPVQQKTIKPILSSEDHDVIARAKTGTGKTF
AFLIPIFQHLINTKFDSQYMVKAVIVAPTRDLALQIEAEVKKIHDMNYGLKKYACVSL
VGGTDFRAAMNKMNKLRPNIVIATPGRLIDVLEKYSNKFFRFVDYKVLDEADRLLEIG
FRDDLETISGILNEKNSKSADNIKTLLFSATLDDKVQKLANNIMNKKECLFLDTVDKN
EPEAHERIDQSVVISEKFANSIFAAVEHIKKQIKERDSNYKAIIFAPTVKFTSFLCSI
LKNEFKKDLPILEFHGKITQNKRTSLVKRFKKDESGILVCTDVGARGMDFPNVHEVLQ
IGVPSELANYIHRIGRTARSGKEGSSVLFICKDELPFVRELEDAKNIVIAKQEKYEPS
EEIKSEVLEAVTEEPEDISDIVISLISSYRSCIKEYRFSERRILPEIASTYGVLLNDP
QLKIPVSRRFLDKLGLSRSPIGKAMFEIRDYSSRDGNNKSYDYDDDSEISFRGNKNYN
NRSQNRDYDDEPFRRSNNNRRSFSRSNDKNNYSSRNSNIY"
gene 848071..848223
/locus_tag="YDR194W-A"
/db_xref="GeneID:1466435"
mRNA 848071..848223
/locus_tag="YDR194W-A"
/product="hypothetical protein"
/transcript_id="NM_001184546.1"
/db_xref="GI:296143545"
/db_xref="GeneID:1466435"
CDS 848071..848223
/locus_tag="YDR194W-A"
/note="hypothetical protein; identified by fungal homology
and RT-PCR"
/codon_start=1
/product="hypothetical protein"
/protein_id="NP_878064.1"
/db_xref="GI:33438782"
/db_xref="SGD:S000028541"
/db_xref="GeneID:1466435"
/translation="MKQMMIEASISKDTLRLLICFFEIKQCHISLQPTCYYQNWVRYS
SIYYQL"
gene 848599..850200
/gene="REF2"
/locus_tag="YDR195W"
/db_xref="GeneID:851776"
mRNA 848599..850200
/gene="REF2"
/locus_tag="YDR195W"
/product="Ref2p"
/transcript_id="NM_001180503.3"
/db_xref="GI:398366050"
/db_xref="GeneID:851776"
CDS 848599..850200
/gene="REF2"
/locus_tag="YDR195W"
/note="RNA-binding protein involved in the cleavage step
of mRNA 3'-end formation prior to polyadenylation, and in
snoRNA maturation; part of holo-CPF subcomplex APT, which
associates with 3'-ends of snoRNA- and mRNA-encoding
genes"
/codon_start=1
/product="Ref2p"
/protein_id="NP_010481.3"
/db_xref="GI:398366051"
/db_xref="SGD:S000002603"
/db_xref="GeneID:851776"
/translation="MSAPVPQLVNISHALQASTIQQIRLDMVDFNKDCKLSSIQLARI
DKYIDSLQAALNQFTKDNLHIERKEKNVTEADIQLYSGLKSMYLDYLNQLIKLKHEKQ
HHSTPPIANDVSLDFFVNQLPKFSPEERKNYIDNLILNKNSHNRLSKMDGLVDAVINL
CVLDTSVAENVRSYMKLLDTLGFQKGSNSTGTKANLKKKLASSKAKIKDSEKEKEKEK
DKSKVKMKTKLKPSPLLNNDDKNSSPSPTASTSSMKKLKSGLFNKNEAKSTESLPTSS
KKKLSFSKYLNKDDADMTKLGTKRSIDVDFKVNPEASTVASNIISSSTSGSSTTTVAT
PASSEEPLKKKTKISVQDSNVQSILRNGKPKKARISSIKFLDDSQLIKVYGDDLPNQG
LQVSPTQLKKILKPFKEGEPKEIILFEDMSIKLKPLDLMFLKNTNSDDYMDISETKGG
PIHCETRTPLIYRKNFNHFNPDLNKRPPREPIEFDLNGNTNSTPTIAKAFGKNSLLLR
KDRGGLPYKHVPIVKRNKYPPRPVH"
gene complement(850274..850999)
/gene="CAB5"
/locus_tag="YDR196C"
/db_xref="GeneID:851777"
mRNA complement(850274..850999)
/gene="CAB5"
/locus_tag="YDR196C"
/product="putative dephospho-CoA kinase"
/transcript_id="NM_001180504.3"
/db_xref="GI:398366056"
/db_xref="GeneID:851777"
CDS complement(850274..850999)
/gene="CAB5"
/locus_tag="YDR196C"
/note="Probable dephospho-CoA kinase (DPCK) that catalyzes
the last step in coenzyme A biosynthesis; null mutant
lethality is complemented by E. coli coaE (encoding DPCK);
detected in purified mitochondria in high-throughput
studies"
/codon_start=1
/product="putative dephospho-CoA kinase"
/protein_id="NP_010482.3"
/db_xref="GI:398366057"
/db_xref="SGD:S000002604"
/db_xref="GeneID:851777"
/translation="MLVVGLTGGIACGKSTVSRRLRDKYKLPIVDADKIARQVVEPGQ
NAYDQIVLYFKDKIPNLLLEDGHLNREALGKWVFSHKEDLQALNGITHPAIRYAMFKE
IGYYYLKGYRMCVLDVPLLFEGNLDSICGVTVSVICTQELQLERLMTRNPELSEEDAK
NRLNSQMSTEERMARSDYILQNNSTLVDLYEQIESVVKKIQPSKLRTVLEYFPPFGAV
SASSIVMSRLLMKKLQNKKSSAV"
gene 851228..852397
/gene="CBS2"
/locus_tag="YDR197W"
/gene_synonym="CBP7"
/db_xref="GeneID:851778"
mRNA 851228..852397
/gene="CBS2"
/locus_tag="YDR197W"
/gene_synonym="CBP7"
/product="Cbs2p"
/transcript_id="NM_001180505.1"
/db_xref="GI:296143548"
/db_xref="GeneID:851778"
CDS 851228..852397
/gene="CBS2"
/locus_tag="YDR197W"
/gene_synonym="CBP7"
/note="Mitochondrial translational activator of the COB
mRNA; interacts with translating ribosomes, acts on the
COB mRNA 5'-untranslated leader"
/codon_start=1
/product="Cbs2p"
/protein_id="NP_010483.1"
/db_xref="GI:6320403"
/db_xref="SGD:S000002605"
/db_xref="GeneID:851778"
/translation="MSSSIPRVYSLGNSAMTYLLALRIAQLPSQPKVPSVVLLLNDQK
KLNRFLNNDSKIIVKSSNNNKETYHRQFMASCVPPILSNGEIAPIENLIVSDPSSKFI
TAQLSKYNKSLRPETNILFLNPSLNLLEHLHRYRWRFDEARPNLFMGFTTPVDVGTIH
QEFQLSLKVKGRIQFHIAKIDGFPRMSSTGKSASLSLRGDRQKNEKENNAFYKLFREI
SRLRSGIGSDLVSFDLHVHGFQDLFFTELEKLILESCTEPLLAVYDCVYKKELLKIPG
AQDIIKKLISEQLSIIDRSYPSLNTNPNYSVIFDKERIFSLVMRDLEVNGHKRAKLAQ
SLNQLNQTNINELNGFFVSLGKYKKCNCKWNDILLTLIKGKQFITKQKALDYHYL"
gene complement(852533..853972)
/gene="RKM2"
/locus_tag="YDR198C"
/db_xref="GeneID:851779"
mRNA complement(852533..853972)
/gene="RKM2"
/locus_tag="YDR198C"
/product="Rkm2p"
/transcript_id="NM_001180506.1"
/db_xref="GI:296143549"
/db_xref="GeneID:851779"
CDS complement(852533..853972)
/gene="RKM2"
/locus_tag="YDR198C"
/EC_number="2.1.1.-"
/note="Ribosomal protein lysine methyltransferase,
responsible for trimethylation of the lysine residue at
position 3 of Rpl12Ap and Rpl12Bp"
/codon_start=1
/product="Rkm2p"
/protein_id="NP_010484.1"
/db_xref="GI:6320404"
/db_xref="SGD:S000002606"
/db_xref="GeneID:851779"
/translation="MEGKVDVLLTWLKKSDKFYIAPNISICESPETGRGIVLSHGSIR
KNDIIVSVPSSKQLNFHTILYHISKFNKELNIPGITIDRKPINYEDNIIEAENKAWAD
PRYGLYSELSKEFLLSLSSFQLVSFYILVENFLLPKWTHNEIYSDWKPFFDVWPSMEE
LRSIPAIWNCDPNSRYHSLIEYLPAASRKHMARISGLVREDWETISEVVLKWNEIYGS
LSCTKNSDKFTSDELFSLFVHVYFIINSRCLYAKIPLKIEDSPSNFTLVPYVDFMNHI
CESDLHCYPQLSPQLRSEGENIIGIGQFTIRCGDHLYDNINEELFLNYGAHSNDFLLN
EYGFVVDGNKWNYLDISDEIIELIDDDKKEVKTFLLEHDYWGDYTINETDISYRIFVA
LNYYVTRDERRVRKFIEGYISEDYFKPKISSVLKELLVSLTAKYTKTLSELTEKVSNL
ENNLCLQNLITIYKGYIKILTQHLQDLQS"
gene complement(854279..856093)
/gene="VPS64"
/locus_tag="YDR200C"
/gene_synonym="FAR9"
/db_xref="GeneID:851781"
mRNA complement(854279..856093)
/gene="VPS64"
/locus_tag="YDR200C"
/gene_synonym="FAR9"
/product="Vps64p"
/transcript_id="NM_001180508.3"
/db_xref="GI:398366070"
/db_xref="GeneID:851781"
CDS complement(854279..856093)
/gene="VPS64"
/locus_tag="YDR200C"
/gene_synonym="FAR9"
/note="Protein required for cytoplasm to vacuole targeting
of proteins; forms a complex with Far3p and Far7p to
Far11p involved in recovery from pheromone-induced cell
cycle arrest; mutant has increased aneuploidy tolerance"
/codon_start=1
/product="Vps64p"
/protein_id="NP_010486.3"
/db_xref="GI:398366071"
/db_xref="SGD:S000002608"
/db_xref="GeneID:851781"
/translation="MVELEKRRRPPPQLQHSPYVRDQSNSQGMTKTPETSPPKRPMGR
ARSNSRSSGSRSNVDIDQYTIPPGLDLLPTASSPPSVHQVSQQQQLSPILANKIRSPF
ENQSQDQNDNSIDPTPAGQVTIPVEAVSPPALDELSKFQNGSTETLFRTGSPRKKHTH
IIILKSLNATFETKFLVVPFKPDGLKLGRPVTNSVNKNNSGSKRDLFSQQVRPDNGNF
DSRVLSRNHACLSCDPTSGKIYIRDLKSSNGTFVNGVKIRQNDVELKVGDTVDLGTDI
DSKFEHRKISAYVEEISVIPLMNTVSDPTNLVMKKQDHTNKNNGNSTNINGIKIDRGH
HNQHIPIRSHLKENYTEAGVTSATTAQRAAFEAAMFGDINNSELDDDILGPETEVLSG
IFINNSAGTSINLINMIKTLTTELSLEKQELEKLHSMQNFMQNYTINLDFINKHMIDM
NEKHLLKLSTALQKTLSENNDALLKESEDQLKEIKQQNNKVKSACSLKEKQNHEKLQE
LESELRELNLQIEEERGKNLVLTQSNFNGGINNDNNAKVKQNDSREEKKDTEDTLIST
EELGVVEGKRTRVSKGMLFGVVAISFGLVATAVKQLPQ"
gene 856317..856814
/gene="SPC19"
/locus_tag="YDR201W"
/db_xref="GeneID:851782"
mRNA 856317..856814
/gene="SPC19"
/locus_tag="YDR201W"
/product="Spc19p"
/transcript_id="NM_001180509.3"
/db_xref="GI:398366076"
/db_xref="GeneID:851782"
CDS 856317..856814
/gene="SPC19"
/locus_tag="YDR201W"
/note="Essential subunit of the Dam1 complex (aka DASH
complex), couples kinetochores to the force produced by MT
depolymerization thereby aiding in chromosome segregation;
also localized to nuclear side of spindle pole body"
/codon_start=1
/product="Spc19p"
/protein_id="NP_010487.3"
/db_xref="GI:398366077"
/db_xref="SGD:S000002609"
/db_xref="GeneID:851782"
/translation="MTDALEQSVLALEGTVSVLKDSVESLKCANEPSTNLASTMLQTK
RVFRLVPEYDVERSKLDLIEEVEPLVRTLGDKLRKSMGRMQRELDTLQQTYELNDLRL
KKNISMDDDDALNSPDMGQEYEGRDADDVVMMASSTNEELEELKKLKEKKKQLENKLE
ILKQK"
gene complement(856898..857953)
/gene="RAV2"
/locus_tag="YDR202C"
/db_xref="GeneID:851784"
mRNA complement(856898..857953)
/gene="RAV2"
/locus_tag="YDR202C"
/product="Rav2p"
/transcript_id="NM_001180510.1"
/db_xref="GI:296143552"
/db_xref="GeneID:851784"
CDS complement(856898..857953)
/gene="RAV2"
/locus_tag="YDR202C"
/note="Subunit of RAVE (Rav1p, Rav2p, Skp1p), a complex
that associates with the V1 domain of the vacuolar
membrane (H+)-ATPase (V-ATPase) and promotes assembly and
reassembly of the holoenzyme"
/codon_start=1
/product="Rav2p"
/protein_id="NP_010488.1"
/db_xref="GI:6320409"
/db_xref="SGD:S000002610"
/db_xref="GeneID:851784"
/translation="MSVDLFPNDRFGAEDKYDNFKDAVKECSWLIEEIVKPQLPNIID
NFSKCLEMLESDQIFKMPVSNGIPNESNKQNDSPTVKGVITRQGQYIVDFHIVVRFPQ
FQRGKQVMFRMNTGLNFLLIQFSKIMTHLKNILEILNQLQVATDVSEFVSKFGVAMEL
LNHSLILLQNPPRDLVFPEDNNFAMKEMFQDCYSVCESTAHILGLELTLCRNELCIEL
RNLIKVTKKPWCEIDSKTGRSFCDQIRNQVTNERNKTLSKILSENGVQVQDSTLLNHI
ISSFQSEAITLPEAQELLRRGVTFDNRVVMECEKLIVSTSDPTLISISAKLNSLKASM
ANHQANLVASKQLSTYK"
gene 858137..859144
/gene="COQ4"
/locus_tag="YDR204W"
/db_xref="GeneID:851785"
mRNA 858137..859144
/gene="COQ4"
/locus_tag="YDR204W"
/product="Coq4p"
/transcript_id="NM_001180512.1"
/db_xref="GI:296143553"
/db_xref="GeneID:851785"
CDS 858137..859144
/gene="COQ4"
/locus_tag="YDR204W"
/note="Protein with a role in ubiquinone (Coenzyme Q)
biosynthesis, possibly functioning in stabilization of
Coq7p; located on the matrix face of the mitochondrial
inner membrane; component of a mitochondrial
ubiquinone-synthesizing complex"
/codon_start=1
/product="Coq4p"
/protein_id="NP_010490.1"
/db_xref="GI:6320410"
/db_xref="SGD:S000002612"
/db_xref="GeneID:851785"
/translation="MLRLSLLRSTATLPVKCQRRGLILPAAAMYTLGSLIFGKEARLA
DAMERGELHNKNVDYAKEAEERTELRIRALANTRPMEPRYNGHVPLHRYEKLLLFAIS
GWNSFFHPEDGYNIVQLGEATALPVFLENLKQTMLSDSSGRRILKEQPNITTEILHMD
KLAKLPHNTFGYVYYQWLKRENVSPDTRAPVKFIDDPMHAYIFKRYRQCHDFYHAITN
MPIIIEGEITIKALEGANLGVPMAILGGILAPLRLKKVQRKRLYNIYLPWAVRTGLSC
KPLINVYWEEMLEKDVTALRKELKITLPPDLRTMRKERAALRKEIDAKYNSQKRATTP
A"
gene 859346..861520
/gene="MSC2"
/locus_tag="YDR205W"
/db_xref="GeneID:851786"
mRNA 859346..861520
/gene="MSC2"
/locus_tag="YDR205W"
/product="metal cation transporter MSC2"
/transcript_id="NM_001180513.3"
/db_xref="GI:398366086"
/db_xref="GeneID:851786"
CDS 859346..861520
/gene="MSC2"
/locus_tag="YDR205W"
/note="Member of the cation diffusion facilitator family,
localizes to the endoplasmic reticulum and nucleus;
mutations affect the cellular distribution of zinc and
also confer defects in meiotic recombination between
homologous chromatids"
/codon_start=1
/product="metal cation transporter MSC2"
/protein_id="NP_010491.4"
/db_xref="GI:398366087"
/db_xref="SGD:S000002613"
/db_xref="GeneID:851786"
/translation="MNLQELLAKVPLLLSYPTIILSSNLIVPSHNDLISRAASTSAAE
YADEKLIFFSTDHAIRLIFLPTFVASSFNLFAHYFNFINYSSRRKYYVLFTAIYFLSI
LTAIFHPIQSTCITLLIIKLLTTADESSPKIALNFKTILKTFVPFITLTLVILRWDPS
FDASSGDVNKISTSLAAYALLILTLRYASPLILSTLSSSIGVVSKDTSVAQHSISRNK
RFPLILVLPIFSFVLLYLMTIVNKTYNIQLLMVFVFFGCLSIFFLSLKDLFTEDGNQK
KGGQEDEYCRMFDIKYMISYLWLTRFTILLTGIMAIVVHFLSFNEITSSIKTDLLSLL
FVVVAEYVSSFSNKQPDSHSHNHAHHHSHLTDSLPLENESMFKQMALNKDTRSIFSFL
LLNTAFMFVQLLYSFRSKSLGLLSDSLHMALDCTSLLLGLIAGVLTKKPASDKFPFGL
NYLGTLAGFTNGVLLLGIVCGIFVEAIERIFNPIHLHATNELLVVATLGLLVNLVGLF
AFDHGAHDHGGTDNENMKGIFLHILADTLGSVGVVISTLLIKLTHWPIFDPIASLLIG
SLILLSALPLLKSTSANILLRLDDKKHNLVKSALNQISTTPGITGYTTPRFWPTESGS
SGHSHAHTHSHAENHSHEHHHDQKNGSQEHPSLVGYIHVQYVDGENSTIIKKRVEKIF
ENVSIKAWVQVEPQNSTCWCRATSMNTISANPNSLPLQPIAN"
gene 862054..864708
/gene="EBS1"
/locus_tag="YDR206W"
/db_xref="GeneID:851787"
mRNA 862054..864708
/gene="EBS1"
/locus_tag="YDR206W"
/product="Ebs1p"
/transcript_id="NM_001180514.3"
/db_xref="GI:398366092"
/db_xref="GeneID:851787"
CDS 862054..864708
/gene="EBS1"
/locus_tag="YDR206W"
/note="Protein involved in inhibition of translation and
nonsense-mediated decay; interacts with cap binding
protein Cdc33p and with Nam7p; localizes to P-bodies upon
glucose starvation; mRNA abundance regulated by mRNA decay
factors"
/codon_start=1
/product="Ebs1p"
/protein_id="NP_010492.3"
/db_xref="GI:398366093"
/db_xref="SGD:S000002614"
/db_xref="GeneID:851787"
/translation="MEPSNTQKEDLPTAFNGIKSQLNSILKSNQLFQDYALLNGFLAF
VHSKLNAAILTSIESQCGKSFAADLDSFDQSSISSILDFSWESVHYPIFKWFQMWRNY
ILFEKENKKQQTKFIDFRKMNSKMLKFFKTVQNFYVNVINTVYKKYDISVLLPKRIIQ
DLKLSDIENTTNVGDILAVKTFNSSSPLAHLIPTLFHRCLLFLGTAYRYKTLLEEISN
KYSISNFKKSLDFFRLASLVLPSAGETYSQAGAIFLQTGNLGIAVFNFVKGMMTKMPS
PVSIKNFGALMVDNKSSLNRSLHTTIMNTYLQESKGPRTPAKEILEFYFLGLFGSVWS
PTSWRDDTKPNQLNNGIKLRHLENALYETMSARYLNNIKTIFHNLIITIGGFHLLLKR
RSDVSAKTLKDLRSNELDYLNFAFKYIAHILNDIVKESWSENPEVSEILGMVRIINCW
IKANPMVLQYSQSNLEFVNALAYLINDIVKKKPSPSFSITEHIPKRTYWFEEDLMVKG
LSFVNFQLSDFDDYEKILEMDHSLDRLIGNPPLCDKLSASSEMLLRLQAVVNISSQLL
QNNNCGVEWSDNKSRYIFNKKIGFKETVKNSMKTSKQSNEKAKLQRKNKPSTTNGSIS
MADLERQMRSSSLDSFSPTMGYSGSSVPMAPDTFNVKPSGTITGNKVNVELLKIELSG
QNADGAITNISPGYSNAAISSSNSTDESSFDLNNILSSMQQKHAEKSFAKSMQGVNEQ
IPANDVCHQAQRPMQGGLYSSQQPSSMSSLNSAYQNASMPPSASMVSYPYPFLNQQGQ
GVFPPYNAQNLQWQSEAYSLKSMNFANPTWLGDQYQTSAPSSAYAQAQRQMFQQPMQQ
DVGKYMQFPFDAQSNTDSMRGNSRNNMF"
gene complement(865012..867522)
/gene="UME6"
/locus_tag="YDR207C"
/gene_synonym="CAR80; NIM2; RIM16"
/db_xref="GeneID:851788"
mRNA complement(865012..867522)
/gene="UME6"
/locus_tag="YDR207C"
/gene_synonym="CAR80; NIM2; RIM16"
/product="Ume6p"
/transcript_id="NM_001180515.1"
/db_xref="GI:296143556"
/db_xref="GeneID:851788"
CDS complement(865012..867522)
/gene="UME6"
/locus_tag="YDR207C"
/gene_synonym="CAR80; NIM2; RIM16"
/note="Key transcriptional regulator of early meiotic
genes, binds URS1 upstream regulatory sequence, couples
metabolic responses to nutritional cues with initiation
and progression of meiosis, forms complex with Ime1p, and
also with Sin3p-Rpd3p"
/codon_start=1
/product="Ume6p"
/protein_id="NP_010493.1"
/db_xref="GI:6320413"
/db_xref="SGD:S000002615"
/db_xref="GeneID:851788"
/translation="MLDKARSQSKHMDESNAAASLLSMETTANNHHYLHNKTSRATLM
NSSQDGKKHAEDEVSDGANSRHPTISSASIESLKTTYDENPLLSIMKSTCAPNNTPVH
TPSGSPSLKVQSGGDIKDDPKENDTTTTTNTTLQDRRDSDNAVHAAASPLAPSNTPSD
PKSLCNGHVAQATDPQISGAIQPQYTATNEDVFPYSSTSTNSNTATTTIVAGAKKKIH
LPPPQAPAVSSPGTTAAGSGAGTGSGIRSRTGSDLPLIITSANKNNGKTTNSPMSILS
RNNSTNNNDNNSIQSSDSRESSNNNEIGGYLRGGTKRGGSPSNDSQVQHNVHDDQCAV
GVAPRNFYFNKDREITDPNVKLDENESKINISFWLNSKYRDEAYSLNESSSNNASSNT
DTPTNSRHANTSSSITSRNNFQHFRFNQIPSQPPTSASSFTSTNNNNPQRNNINRGED
PFATSSRPSTGFFYGDLPNRNNRNSPFHTNEQYIPPPPPKYINSKLDGLRSRLLLGPN
SASSSTKLDDDLGTAAAVLSNMRSSPYRTHDKPISNVNDMNNTNALGVPASRPHSSSF
PSKGVLRPILLRIHNSEQQPIFESNNSTAVFDEDQDQNQDLSPYHLNLNSKKVLDPTF
ESRTRQVTWNKNGKRIDRRLSAPEQQQQLEVPPLKKSRRSVGNARVASQTNSDYNSLG
ESSTSSAPSSPSLKASSGLAYTADYPNATSPDFAKSKGKNVKPKAKSKAKQSSKKRPN
NTTSKSKANNSQESNNATSSTSQGTRSRTGCWICRLRKKKCTEERPHCFNCERLKLDC
HYDAFKPDFVSDPKKKQMKLEEIKKKTKEAKRRAMKKK"
gene 868224..870563
/gene="MSS4"
/locus_tag="YDR208W"
/db_xref="GeneID:851789"
mRNA 868224..870563
/gene="MSS4"
/locus_tag="YDR208W"
/product="1-phosphatidylinositol-4-phosphate 5-kinase"
/transcript_id="NM_001180516.1"
/db_xref="GI:296143557"
/db_xref="GeneID:851789"
CDS 868224..870563
/gene="MSS4"
/locus_tag="YDR208W"
/EC_number="2.7.1.68"
/note="Phosphatidylinositol-4-phosphate 5-kinase, involved
in actin cytoskeleton organization and cell morphogenesis;
multicopy suppressor of stt4 mutation"
/codon_start=1
/product="1-phosphatidylinositol-4-phosphate 5-kinase"
/protein_id="NP_010494.1"
/db_xref="GI:6320414"
/db_xref="SGD:S000002616"
/db_xref="GeneID:851789"
/translation="MSVLRSQPPSVVPLHLTTSTSRKTEQEPSLLHSAIIERHQDRSV
PNSNSNPDSNHRIKKDRNNHTSYHSSSNSESNMESPRLSDGESSTPTSIEELNPTINN
SRLVKRNYSISIDPLHDNSNNNTDDDHPNTITSPRPNSTSNKEMQKYSFPEGKESKKI
TTPSLNSNNCLDLDNSSLVHTDSYIQDLNDDHILLNKRVSRRSSRISAVTATSTTIKQ
RRNTQDSNLPNIPFHASKHSQILPMDDSDVIKLANGDTSMKPNSATKISHSMTSLPLH
PLPQPSQKSKQYHMISKSTTSLPPENDHYYQHSRGTNHNHAANAAAVNNNTTTTTAAT
GLKRSESATAEIKKMRQSLLHKREMKRKRKTFLVDDDRVLIGNKVSEGHVNFIIAYNM
LTGIRVAVSRCSGIMKPLTPADFRFTKKLAFDYHGNELTPSSQYAFKFKDYCPEVFRE
LRALFGLDPADYLVSLTSKYILSELNSPGKSGSFFYYSRDYKYIIKTIHHSEHIHLRK
HIQEYYNHVRDNPNTLICQFYGLHRVKMPISFQNKIKHRKIYFLVMNNLFPPHLDIHI
TYDLKGSTWGRFTNLDKERLAKDRSYRPVMKDLNWLEEGQKIKFGPLKKKTFLTQLKK
DVELLAKLNTMDYSLLIGIHDINKAKEDDLQLADTASIEEQPQTQGPIRTGTGTVVRH
FFREFEGGIRASDQFNNDVDLIYYVGIIDFLTNYSVMKKLETFWRSLRHDTKLVSAIP
PRDYANRFYEFIEDSVDPLPQKKTQSSYRDDPNQKNYKD"
gene 871074..871301
/locus_tag="YDR210W"
/db_xref="GeneID:851790"
mRNA 871074..871301
/locus_tag="YDR210W"
/product="hypothetical protein"
/transcript_id="NM_001180518.3"
/db_xref="GI:398366108"
/db_xref="GeneID:851790"
CDS 871074..871301
/locus_tag="YDR210W"
/note="Predicted tail-anchored plasma membrane protein
containing a conserved CYSTM module; related proteins in
other organisms may be involved in response to stress;
green fluorescent protein (GFP)-fusion protein localizes
to the cell periphery"
/codon_start=1
/product="hypothetical protein"
/protein_id="NP_010496.3"
/db_xref="GI:398366109"
/db_xref="SGD:S000002618"
/db_xref="GeneID:851790"
/translation="MSQQQGYYQQGPPQQGYYQQGPPQQGYYQQGPPQQGYPQQQPVY
VQQGQPKEESCLDSCLKCLCCCFLLELVCDN"
mobile_element 871821..877779
/note="YDRWTy2-2; Ty2 element, LTR retrotransposon of the
Copia (Pseudoviridae) group; contains co-transcribed genes
TYA Gag and TYB Pol, encoding proteins involved in
structure and function of virus-like particles, flanked by
two direct repeats"
/mobile_element_type="retrotransposon:YDRWTy2-2"
/db_xref="SGD:S000006884"
LTR 871821..872152
/note="Ty1 LTR"
/db_xref="SGD:S000006867"
gene 872112..877425
/locus_tag="YDR210W-B"
/db_xref="GeneID:851793"
mRNA join(<872112..873404,873406..>877425)
/locus_tag="YDR210W-B"
/transcript_id="NM_001184419.3"
/db_xref="GI:398366114"
/db_xref="GeneID:851793"
CDS join(872112..873404,873406..877425)
/locus_tag="YDR210W-B"
/EC_number="2.7.7.49"
/EC_number="3.4.23.-"
/EC_number="3.1.26.4"
/EC_number="2.7.7.7"
/ribosomal_slippage
/note="Retrotransposon TYA Gag and TYB Pol genes;
transcribed/translated as one unit; polyprotein is
processed to make a nucleocapsid-like protein (Gag),
reverse transcriptase (RT), protease (PR), and integrase
(IN); similar to retroviral genes"
/codon_start=1
/product="gag-pol fusion protein"
/protein_id="NP_058142.3"
/db_xref="GI:398366115"
/db_xref="SGD:S000007393"
/db_xref="GeneID:851793"
/translation="MESQQLHQNPHSQHGSAYASVTSKEVPSNQDPLAVSASNLPEFD
RDSTKVNSQEETTPGTSAVPENHHHVSPQPASVPPPQNGQYQQHGMMTPNKAMASNWA
HYQQPSMMTCSHYQTSPAYYQPDPHYPLPQYIPPLSTSSPDPIDSQDQHSEVPQAKTK
VRNNVLPPHTLTSEENFSTWVKFYIRFLKNSNLGDIIPNDQGEIKRQMTYEEHAYIYN
TFQAFAPFHLLPTWVKQILEINYSDILTVLCKSVSKMQTNNQELKDWIALANLEYNGS
TSADTFEITVSTIIQRLKENNINVSDRLACQLILKGLSGDFKYLRNQYRTKTNMKLSQ
LFAEIQLIYDENKIMNLNKPSQYKQHSEYKNVSRTSPNTTNTKVTTRNYHRTNSSKPR
AAKAHNIATSSKFSRVNSDHINESTVSSQYLSDDNELSLGQQQKESKPTRTIDSNDEL
PDHLLIDSGASQTLVRSAHYLHHATPNSEINIVDAQKQDIPINAIGNLHFNFQNGTKT
SIKALHTPNIAYDLLSLSELANQNITACFTRNTLERSDGTVLAPIVKHGDFYWLSKKY
LIPSHISKLTINNVNKSKSVNKYPYPLIHRMLGHANFRSIQKSLKKNAVTYLKESDIE
WSNASTYQCPDCLIGKSTKHRHVKGSRLKYQESYEPFQYLHTDIFGPVHHLPKSAPSY
FISFTDEKTRFQWVYPLHDRREESILNVFTSILAFIKNQFNARVLVIQMDRGSEYTNK
TLHKFFTNRGITACYTTTADSRAHGVAERLNRTLLNDCRTLLHCSGLPNHLWFSAVEF
STIIRNSLVSPKNDKSARQHAGLAGLDITTILPFGQPVIVNNHNPDSKIHPRGIPGYA
LHPSRNSYGYIIYLPSLKKTVDTTNYVILQNNQTKLDQFDYDTLTFDDDLNRLTAHNQ
SFIEQNETEQSYDQNTESDHDYQSEIEINSDPLVNDFSSQSLNPLQLDKEPVQKVRAP
KEVDADISEYNILPSTIRSRTPHIINKESTEMGGTIESDTTSPRHSSTFTARNQKRPG
SPNDMIDLTSQDRVNYGLENIKTTRLGGTEEPYIQRNSDTNIKYRTTNSTPSIDDRSS
NSESTTPIISIETKAVCDNTPSIDTDPPEYRSSDHATPNIMPDKSSKNVTADSILDDL
PLPDLTHKSPTDTSDVAKDIPHIHSRQTNSSLGGMDDSNVLTTTKSKKRSLEDNETEI
EVSRDTWNNKNMRSLEPPRSKKRINLIAAIKGVKSIKPVRTTLRYDEAITYNKDNKEK
DRYVEAYHKEISQLLKMNTWDTNKYYDRNDIDPKKVINSMFIFNKKRDGTHKARFVAR
GDIQHPDTYDSDMQSNTVHHYALMTSLSIALDNDYYITQLDISSAYLYADIKEELYIR
PPPHLGLNDKLLRLRKSLYGLKQSGANWYETIKSYLINCCDMQEVRGWSCVFKNSQVT
ICLFVDDMILFSKDLNANKKIITTLKKQYDTKIINLGEGDNEIQYDILGLEIKYQRSK
YMKLGMEKSLTEKLPKLNVPLNPKGKKLRAPGQPGHYIDQDELEIDEDEYKEKVHEMQ
KLIGLASYVGYKFRFDLLYYINTLAQHILFPSRQVLDMTYELIQFMWDTRDKQLIWHK
NKPTKPDNKLVAISDASYGNQPYYKSQIGNIFLLNGKVIGGKSTKASLTCTSTTEAEI
HAVSEAIPLLNNLSHLVQELNKKPIIKGLLTDSRSTISIIKSTNEEKFRNRFFGTKAM
RLRDEVSGNNLYVYYIETKKNIADVMTKPLPIKTFKLLTNKWIH"
gene 872112..873428
/locus_tag="YDR210W-A"
/db_xref="GeneID:851792"
mRNA <872112..>873428
/locus_tag="YDR210W-A"
/transcript_id="NM_001184418.1"
/db_xref="GI:296143559"
/db_xref="GeneID:851792"
CDS 872112..873428
