LOCUS NC_001139 1090940 bp DNA linear PLN 25-FEB-2013
DEFINITION Saccharomyces cerevisiae S288c chromosome VII, complete sequence.
ACCESSION NC_001139
VERSION NC_001139.9 GI:330443578
DBLINK Project: 128
KEYWORDS TPA:inferential.
SOURCE Saccharomyces cerevisiae S288c
ORGANISM Saccharomyces cerevisiae S288c
Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina;
Saccharomycetes; Saccharomycetales; Saccharomycetaceae;
Saccharomyces.
REFERENCE 1 (bases 1 to 1090940)
AUTHORS Tettelin,H., Agostoni Carbone,M.L., Albermann,K., Albers,M.,
Arroyo,J., Backes,U., Barreiros,T., Bertani,I., Bjourson,A.J.,
Bruckner,M., Bruschi,C.V., Carignani,G., Castagnoli,L., Cerdan,E.,
Clemente,M.L., Coblenz,A., Coglievina,M., Coissac,E., Defoor,E.,
Del Bino,S., Delius,H., Delneri,D., de Wergifosse,P., Dujon,B.,
Kleine,K. et al.
TITLE The nucleotide sequence of Saccharomyces cerevisiae chromosome VII
JOURNAL Nature 387 (6632 SUPPL), 81-84 (1997)
PUBMED 9169869
REFERENCE 2 (bases 1 to 1090940)
AUTHORS Goffeau,A., Barrell,B.G., Bussey,H., Davis,R.W., Dujon,B.,
Feldmann,H., Galibert,F., Hoheisel,J.D., Jacq,C., Johnston,M.,
Louis,E.J., Mewes,H.W., Murakami,Y., Philippsen,P., Tettelin,H. and
Oliver,S.G.
TITLE Life with 6000 genes
JOURNAL Science 274 (5287), 546 (1996)
PUBMED 8849441
REFERENCE 3 (bases 1 to 1090940)
CONSRTM NCBI Genome Project
TITLE Direct Submission
JOURNAL Submitted (14-FEB-2013) National Center for Biotechnology
Information, NIH, Bethesda, MD 20894, USA
REFERENCE 4 (bases 1 to 1090940)
CONSRTM Saccharomyces Genome Database
TITLE Direct Submission
JOURNAL Submitted (04-MAY-2012) Department of Genetics, Stanford
University, Stanford, CA 94305-5120, USA
REMARK Protein update by submitter
REFERENCE 5 (bases 1 to 1090940)
CONSRTM Saccharomyces Genome Database
TITLE Direct Submission
JOURNAL Submitted (31-MAR-2011) Department of Genetics, Stanford
University, Stanford, CA 94305-5120, USA
REMARK Sequence update by submitter
REFERENCE 6 (bases 1 to 1090940)
CONSRTM Saccharomyces Genome Database
TITLE Direct Submission
JOURNAL Submitted (11-DEC-2009) Department of Genetics, Stanford
University, Stanford, CA 94305-5120, USA
COMMENT PROVISIONAL REFSEQ: This record has not yet been subject to final
NCBI review. The reference sequence is identical to BK006941.
On Apr 26, 2011 this sequence version replaced gi:162949218.
Sequence assembly version R64-1-1.
COMPLETENESS: full length.
PRIMARY REFSEQ_SPAN PRIMARY_IDENTIFIER PRIMARY_SPAN COMP
1-5311 Z72785.1 1-5311
3933-6289 Z72784.1 1-2357
5840-6859 Z72783.1 1-1020
6653-8469 Z72782.1 1-1817
7091-11109 Z72781.1 1-4019
8968-12480 Z72780.1 1-3513
11731-14909 Z72779.1 1-3179
14158-20977 Z72778.1 1-6820
16308-22303 Z72777.1 1-5996
22109-23934 Z72776.1 1-1826
23204-25717 Z72775.1 1-2514
25396-27920 Z72774.1 1-2525
27485-31897 Z72773.1 1-4413
31062-33097 Z72772.1 1-2036
32636-35652 Z72771.1 1-3017
35213-36932 Z72770.1 1-1720
36763-37616 Z72769.1 1-854
37527-38974 Z72768.1 1-1448
38781-41797 Z72767.1 1-3017
41150-43306 Z72766.1 1-2157
43175-44651 Z72765.1 1-1477
44510-45444 Z72764.1 1-935
45198-48513 Z72763.1 1-3316
48460-49430 Z72762.1 1-971
48745-52730 Z72761.1 1-3986
52435-53755 Z72759.1 1-1321
53529-56481 Z72758.1 1-2952
55816-59121 Z72756.1 1-3306
58891-62074 Z72755.1 1-3184
61855-63047 Z72754.1 1-1193
63003-63771 Z72753.1 1-769
63621-64502 Z72752.1 1-882
64216-67597 Z72751.1 1-3382
65489-69670 Z72750.1 1-4182
69332-73339 Z72749.1 1-4007
72548-76893 Z72748.1 1-4345
73712-78014 Z72747.1 1-4303
77908-79111 Z72746.1 1-1204
78858-80658 Z72745.1 1-1801
80366-81425 Z72744.1 1-1060
81187-82373 Z72743.1 1-1187
82293-82877 Z72742.1 1-585
82737-84838 Z72741.1 1-2102
84301-87980 Z72739.1 1-3680
87303-90005 Z72737.1 1-2709
89340-91431 Z72736.1 1-2097
91248-92511 Z72734.1 1-1264
92383-93791 Z72733.1 1-1409
93095-96157 Z72732.1 1-3063
94461-97337 Z72731.1 1-2876
96961-98968 Z72730.1 1-2008
98586-102542 Z72729.1 1-3957
102077-108157 Z72728.1 1-6081
107505-111699 Z72727.1 1-4195
109033-112474 Z72726.1 1-3442
112006-116058 Z72725.1 1-4053
114665-117853 Z72724.1 1-3189
117562-122693 Z72723.1 1-5133
120908-123571 Z72722.1 1-2665
122798-124697 Z72721.1 1-1900
124377-130548 Z72719.1 1-6173
129162-131524 Z72718.1 1-2364
131048-140367 Z72717.1 1-9321
139544-141915 Z72716.1 1-2372
141727-142245 Z72715.1 1-519
142228-144807 Z72714.1 1-2580
144049-145808 Z72713.1 1-1760
145198-148228 Z72712.1 1-3031
147390-149342 Z72711.1 1-1953
148589-149703 Z72710.1 1-1115
149517-151036 Z72709.1 1-1520
150172-153166 Z72708.1 1-2995
152777-154614 Z72707.1 1-1838
154307-156542 Z72706.1 1-2236
156013-157272 Z72705.1 1-1260
157068-157905 Z72704.1 1-838
157597-160064 Z72703.1 1-2468
159097-163408 Z72702.1 1-4312
162759-167351 Z72701.1 1-4593
165092-171414 Z72700.1 1-6323
167907-173284 Z72698.1 1-5378
173080-174544 Z72697.1 1-1465
174323-175526 Z72696.1 1-1204
175346-180699 Z72695.1 1-5354
180114-182389 Z72694.1 1-2276
182119-184152 Z72693.1 1-2034
184085-186058 Z72692.1 1-1974
185395-187463 Z72691.1 1-2069
187340-191128 Z72690.1 1-3789
190469-191977 Z72688.1 1-1509
191977-193706 Z72686.1 1-1730
193301-198137 Z72685.1 1-4837
196404-199209 Z72684.1 1-2806
199038-200560 Z72683.1 1-1523
200143-202720 Z72682.1 1-2578
202274-207032 Z72681.1 1-4758
203834-209005 Z72680.1 1-5171
208572-210415 Z72679.1 1-1844
210050-214080 Z72678.1 1-4031
213668-215277 Z72677.1 1-1610
215212-216272 Z72676.1 1-1061
216097-217523 Z72675.1 1-1427
217370-221103 Z72673.1 1-3734
220923-226398 Z72672.1 1-5476
225878-227753 Z72670.1 1-1876
227530-228750 Z72669.1 1-1221
228330-230242 Z72668.1 1-1913
229687-232449 Z72667.1 1-2763
232349-234716 Z72666.1 1-2368
234508-236268 Z72665.1 1-1761
235959-238352 Z72664.1 1-2394
238120-241352 Z72663.1 1-3233
241086-245715 Z72662.1 1-4630
245013-248493 Z72661.1 1-3481
247559-249868 Z72660.1 1-2310
249532-252896 Z72659.1 1-3365
252739-254640 Z72658.1 1-1902
253860-255662 Z72657.1 1-1803
255295-257706 Z72656.1 1-2412
256965-261579 Z72655.1 1-4615
261502-266144 Z72654.1 1-4643
261696-267722 Z72652.1 1-6027
267525-269292 Z72651.1 1-1769
269189-270391 Z72650.1 1-1203
270337-270996 Z72649.1 1-660
270776-272519 Z72648.1 1-1744
271695-274779 Z72647.1 1-3082
274323-277616 Z72646.1 1-3294
276715-278945 Z72645.1 1-2231
278123-280776 Z72644.1 1-2654
280524-281633 Z72643.1 1-1110
281158-284441 Z72642.1 1-3284
283938-288013 Z72641.1 1-4076
285948-288511 Z72640.1 1-2564
288452-289808 Z72639.1 1-1354
289310-292032 Z72638.1 1-2720
291642-293459 Z72637.1 1-1818
293002-295931 Z72636.1 1-2930
295638-298177 Z72635.1 1-2540
297404-299977 Z72634.1 1-2574
299729-301536 Z72633.1 1-1808
301370-303512 Z72632.1 1-2143
303412-304332 Z72631.1 1-921
304072-306559 Z72629.1 1-2488
306274-307436 Z72628.1 1-1163
307010-308712 Z72627.1 1-1703
308568-310966 Z72626.1 1-2399
309723-312192 Z72625.1 1-2470
311934-313233 Z72623.1 1-1300
312841-314630 Z72622.1 1-1790
314284-317341 Z72621.1 1-3058
316554-321781 Z72620.1 1-5228
318080-325330 Z72619.1 1-7251
323231-328873 Z72618.1 1-5643
326162-331117 Z72617.1 1-4956
330608-334885 Z72616.1 1-4278
334466-337905 Z72615.1 1-3440
337640-342055 Z72614.1 1-4416
341860-343318 Z72613.1 1-1459
343043-344790 Z72612.1 1-1748
344585-345835 Z72611.1 1-1251
345154-346405 Z72610.1 1-1252
345986-347118 Z72609.1 1-1133
346905-349615 Z72608.1 1-2711
349369-350615 Z72607.1 1-1247
350441-353057 Z72606.1 1-2617
352299-355826 Z72605.1 1-3528
355473-357376 Z72604.1 1-1904
356973-358635 Z72603.1 1-1663
358340-359443 Z72602.1 1-1104
359029-360287 Z72601.1 1-1259
360101-362224 Z72600.1 1-2124
361860-364334 Z72599.1 1-2475
363917-366924 Z72598.1 1-3008
365412-368595 Z72597.1 1-3184
368089-372011 Z72596.1 1-3923
371363-374458 Z72593.1 1-3096
374085-375049 Z72592.1 1-965
374828-376100 Z72591.1 1-1273
375672-377608 Z72589.1 1-1937
377256-379759 Z72588.1 1-2504
377951-381522 Z72587.1 1-3572
381272-383653 Z72586.1 1-2382
383209-385195 Z72585.1 1-1987
384767-388967 Z72584.1 1-4201
388733-390064 Z72583.1 1-1334
389712-392222 Z72582.1 1-2513
391991-393985 Z72581.1 1-1995
393562-394965 Z72580.1 1-1405
394505-396034 Z72579.1 1-1530
395830-398627 Z72578.1 1-2795
396286-400870 Z72577.1 1-4582
400161-402588 Z72576.1 1-2428
401288-403436 Z72575.1 1-2149
403303-405775 Z72574.1 1-2473
404392-406859 Z72572.1 1-2468
406598-410068 Z72571.1 1-3471
409605-411551 Z72570.1 1-1947
411287-414101 Z72569.1 1-2816
412161-415041 Z72568.1 1-2878
414892-416145 Z72567.1 1-1252
415731-417482 Z72566.1 1-1752
417037-418911 Z72565.1 1-1876
418594-419526 Z72563.1 1-935
419173-423960 Z72562.1 1-4788
420556-425361 Z72561.1 1-4806
425008-427296 Z72560.1 1-2289
426805-428600 Z72559.1 1-1795
427948-431547 Z72558.1 1-3599
430269-433213 Z72557.1 1-2945
433063-435250 Z72556.1 1-2188
433580-436569 Z72555.1 1-2990
436352-437466 Z72554.1 1-1115
436834-439090 Z72553.1 1-2257
437935-440062 Z72552.1 1-2128
439639-441280 Z72551.1 1-1642
440426-443641 Z72550.1 1-3216
442910-446411 Z72549.1 1-3502
446144-448763 Z72548.1 1-2620
448536-450196 Z72547.1 1-1661
450124-452403 Z72545.1 1-2280
451152-454784 Z72544.1 1-3633
454561-457162 Z72543.1 1-2602
457068-458155 Z72542.1 1-1088
457871-459109 Z72541.1 1-1239
458993-459853 Z72540.1 1-861
459665-461665 Z72539.1 1-2001
461366-465042 Z72538.1 1-3677
464912-466140 Z72537.1 1-1229
465436-469091 Z72536.1 1-3656
468808-472854 Z72535.1 1-4047
472299-474488 Z72534.1 1-2190
474277-475544 Z72533.1 1-1268
475248-476312 Z72532.1 1-1065
476070-479909 Z72531.1 1-3840
478653-483259 Z72530.1 1-4607
482667-485920 Z72529.1 1-3253
483638-489707 Z72528.1 1-6069
489443-490702 Z72527.1 1-1260
490548-492473 Z72526.1 1-1926
491957-494516 Z72525.1 1-2560
494175-495452 Z72524.1 1-1278
495168-497132 Z72523.1 1-1965
496503-498475 Z72786.1 1-1973
497808-500131 Z72787.1 1-2324
499907-502937 Z72788.1 1-3031
502367-504656 Z72789.1 1-2290
504327-506069 Z72790.1 1-1743
505860-506968 Z72791.1 1-1108
506731-508109 Z72792.1 1-1379
507941-509046 Z72793.1 1-1106
508365-511544 Z72794.1 1-3180
511003-513158 Z72795.1 1-2156
512824-514553 Z72797.1 1-1730
514341-516942 Z72798.1 1-2602
516417-521089 Z72799.1 1-4673
520864-522260 Z72800.1 1-1397
522077-523786 Z72801.1 1-1710
522834-525228 Z72802.1 1-2395
524695-526972 Z72804.1 1-2278
526645-527631 Z72805.1 1-987
527330-529256 Z72806.1 1-1927
528505-531882 Z72807.1 1-3378
530920-532638 Z72809.1 1-1719
532597-532984 Z72810.1 1-388
532942-534131 Z72811.1 1-1190
533822-542202 Z72812.1 1-8381
534459-543851 Z72813.1 1-9393
534463-543851 Z72813.1 5-9393
543292-545680 Z72814.1 1-2389
544206-546440 Z72815.1 1-2235
546158-548263 Z72816.1 1-2106
547470-554247 Z72817.1 1-6778
553952-555928 Z72818.1 1-1977
554968-557071 Z72819.1 1-2104
556676-558148 Z72820.1 1-1473
557423-559730 Z72821.1 1-2308
558869-560681 Z72822.1 1-1813
559995-574887 Z72823.1 1-14893
561351-575397 Z72824.1 1-14047
575200-577486 Z72825.1 1-2287
576505-579475 Z72826.1 1-2971
577844-580434 Z72827.1 1-2591
580292-582989 Z72828.1 1-2698
581437-583933 Z72829.1 1-2497
583893-584894 Z72830.1 1-1002
584297-586391 Z72831.1 1-2095
586053-589825 Z72832.1 1-3773
588427-591313 Z72833.1 1-2887
590912-592085 Z72834.1 1-1174
591878-592905 Z72835.1 1-1028
592443-593595 Z72836.1 1-1153
593230-594985 Z72837.1 1-1756
594706-596692 Z72838.1 1-1987
595838-599416 Z72839.1 1-3579
597443-601660 Z72840.1 1-4218
601142-604772 Z72841.1 1-3631
604448-606135 Z72842.1 1-1688
605197-607562 Z72843.1 1-2366
607144-610563 Z72844.1 1-3420
609102-611888 Z72845.1 1-2787
611494-616327 Z72846.1 1-4834
615966-617515 Z72847.1 1-1550
617279-618076 Z72848.1 1-798
617990-620920 Z72850.1 1-2931
619859-622401 Z72851.1 1-2543
621800-625323 Z72852.1 1-3524
624787-627805 Z72853.1 1-3019
627419-631480 Z72855.1 1-4062
631274-634303 Z72856.1 1-3030
634064-635614 Z72857.1 1-1551
635468-637103 Z72858.1 1-1636
636876-637743 Z72861.1 1-868
637578-639771 Z72862.1 1-2194
639514-640719 Z72863.1 1-1206
640372-642009 Z72864.1 1-1638
641833-643147 Z72865.1 1-1315
643009-644043 Z72866.1 1-1035
643781-644859 Z72867.1 1-1079
644596-647122 Z72868.1 1-2527
646816-648382 Z72869.1 1-1567
648143-649597 Z72870.1 1-1455
648908-651289 Z72871.1 1-2382
650618-654600 Z72872.1 1-3983
651383-656959 Z72873.1 1-5577
656323-662357 Z72874.1 1-6035
659771-666340 Z72875.1 1-6570
666072-668188 Z72876.1 1-2117
667826-670387 Z72877.1 1-2562
669908-672185 Z72878.1 1-2278
671912-675670 Z72879.1 1-3759
675501-676620 Z72880.1 1-1120
676442-678694 Z72881.1 1-2253
677566-682565 Z72882.1 1-5000
682136-687898 Z72883.1 1-5763
687459-690244 Z72884.1 1-2786
689966-693362 Z72885.1 1-3397
693098-694583 Z72886.1 1-1486
694404-695416 Z72887.1 1-1013
694761-697444 Z72888.1 1-2684
697235-698598 Z72889.1 1-1364
698369-698988 Z72890.1 1-620
698833-702666 Z72891.1 1-3834
699787-703635 Z72892.1 1-3849
703117-705358 Z72893.1 1-2242
705052-713708 Z72894.1 1-8657
706502-715827 Z72895.1 1-9326
715047-717357 Z72896.1 1-2311
717031-718892 Z72897.1 1-1862
718528-720264 Z72898.1 1-1736
719902-725048 Z72899.1 1-5147
720659-726973 Z72902.1 1-6315
726480-728045 Z72903.1 1-1567
727731-730032 Z72904.1 1-2302
728068-731448 Z72905.1 1-3381
730861-733934 Z72906.1 1-3074
732928-736661 Z72907.1 1-3734
735144-739943 Z72908.1 1-4800
738204-742324 Z72909.1 1-4121
741663-745834 Z72910.1 1-4172
745436-746797 Z72911.1 1-1362
746484-747949 Z72912.1 1-1466
747084-750399 Z72913.1 1-3316
750092-751393 Z72914.1 1-1302
751048-754725 Z72915.1 1-3678
753845-755588 Z72916.1 1-1744
755251-756895 Z72917.1 1-1645
756453-757769 Z72918.1 1-1317
757448-761391 Z72919.1 1-3944
761139-762427 Z72920.1 1-1289
762169-763761 Z72921.1 1-1593
763263-765725 Z72923.1 1-2463
765607-767428 Z72924.1 1-1822
766065-770568 Z72925.1 1-4504
770300-772453 Z72926.1 1-2154
771973-775192 Z72927.1 1-3220
773687-780398 Z72928.1 1-6712
777509-781766 Z72929.1 1-4258
781010-784222 Z72930.1 1-3213
783891-786053 Z72931.1 1-2163
784859-787311 Z72932.1 1-2453
786921-789030 Z72933.1 1-2110
787780-790458 Z72934.1 1-2679
790330-794654 Z72935.1 1-4325
793054-796091 Z72936.1 1-3038
795493-796797 Z72938.1 1-1305
796746-798542 Z72939.1 1-1797
797869-800545 Z72940.1 1-2677
800067-802439 Z72941.1 1-2373
801824-805268 Z72942.1 1-3445
805050-806411 Z72943.1 1-1362
806022-808628 Z72944.1 1-2607
807093-824058 Z72946.1 1-16966
809421-827551 Z72947.1 1-18131
826918-828624 Z72948.1 1-1707
828578-829115 Z72949.1 1-538
828795-830514 Z72950.1 1-1720
830154-832455 Z72951.1 1-2302
832198-833351 Z72952.1 1-1154
832483-834688 Z72953.1 1-2206
834483-837141 Z72954.1 1-2659
835904-840823 Z72955.1 1-4920
840559-842844 Z72956.1 1-2286
842552-843853 Z72957.1 1-1302
843592-845892 Z72958.1 1-2301
844961-846932 Z72959.1 1-1972
846406-848719 Z72960.1 1-2314
848424-851046 Z72961.1 1-2623
850437-853674 Z72963.1 1-3238
853216-855263 Z72964.1 1-2048
854896-858286 Z72965.1 1-3391
856302-859062 Z72966.1 1-2761
858905-859900 Z72968.1 1-996
859477-866335 Z72969.1 1-6859
865754-867773 Z72970.1 1-2020
867521-870231 Z72971.1 1-2711
869982-872043 Z72972.1 1-2062
871417-876668 Z72973.1 1-5252
875110-880295 Z72974.1 1-5186
878193-882811 Z72975.1 1-4619
882232-884508 Z72977.1 1-2277
883811-886072 Z72978.1 1-2262
885742-888881 Z72979.1 1-3140
887876-889732 Z72980.1 1-1857
889291-892496 Z72981.1 1-3206
892187-894692 Z72982.1 1-2506
894141-897501 Z72983.1 1-3361
897147-899903 Z72984.1 1-2757
899782-902519 Z72985.1 1-2738
902271-903473 Z72986.1 1-1203
903345-905236 Z72987.1 1-1892
904749-905933 Z72988.1 1-1185
905684-909212 Z72989.1 1-3529
908775-910431 Z72990.1 1-1657
910086-910842 Z72991.1 1-757
910738-911882 Z72992.1 1-1145
911629-912912 Z72993.1 1-1284
912813-913502 Z72994.1 1-690
913228-915240 Z72995.1 1-2013
914739-917039 Z72996.1 1-2301
916702-918511 Z72997.1 1-1810
918447-920574 Z72998.1 1-2128
919466-922174 Z72999.1 1-2709
921789-922632 Z73000.1 1-844
922508-924695 Z73001.1 1-2186
924463-932540 Z73002.1 1-8076
928243-936034 Z73003.1 1-7792
935796-937123 Z73004.1 1-1328
936884-939922 Z73006.1 1-3039
938993-940868 Z73007.1 1-1876
940805-942805 Z73008.1 1-2001
942216-945144 Z73009.1 1-2929
944648-946400 Z73010.1 1-1753
946375-947419 Z73011.1 1-1044
947002-949364 Z73012.1 1-2363
948998-951893 Z73013.1 1-2896
950900-952533 Z73015.1 1-1634
952308-953959 Z73016.1 1-1653
953481-954673 Z73017.1 1-1193
954647-959903 Z73018.1 1-5258
958211-961359 Z73019.1 1-3150
961104-962428 Z73020.1 1-1325
962062-963297 Z73021.1 1-1238
962818-966038 Z73022.1 1-3222
965656-969186 Z73023.1 1-3531
968688-970770 Z73024.1 1-2083
969686-974874 Z73025.1 1-5189
973735-977335 Z73026.1 1-3601
976724-978035 Z73028.1 1-1312
977777-979764 Z73029.1 1-1988
979320-982481 Z73030.1 1-3162
982069-984965 Z73031.1 1-2897
984273-985971 Z73032.1 1-1699
985686-988048 Z73033.1 1-2363
986740-991175 Z73034.1 1-4436
989420-995638 Z73035.1 1-6219
993522-996868 Z73036.1 1-3347
996230-998357 Z73037.1 1-2128
998189-1000926 Z73038.1 1-2738
999141-1002522 Z73039.1 1-3382
1002241-1004623 Z73040.1 1-2384
1003963-1006204 Z73041.1 1-2243
1006103-1007670 Z73042.1 1-1568
1007306-1012480 Z73043.1 1-5175
1010767-1014320 Z73044.1 1-3554
1014090-1016973 Z73046.1 1-2884
1016751-1017966 Z73047.1 1-1216
1017760-1019597 Z73048.1 1-1838
1018464-1022655 Z73049.1 1-4192
1022059-1025003 Z73051.1 1-2945
1024762-1026056 Z73052.1 1-1295
1025736-1027369 Z73053.1 1-1634
1026963-1031790 Z73055.1 1-4828
1031510-1038041 Z73056.1 1-6532
1037695-1038714 Z73057.1 1-1019
1038502-1039894 Z73058.1 1-1394
1039240-1043188 Z73059.1 1-3950
1043096-1043818 Z73060.1 1-723
1043750-1045643 Z73061.1 1-1894
1045182-1046730 Z73062.1 1-1549
1046562-1048797 Z73063.1 1-2236
1048465-1050909 Z73064.1 1-2445
1049959-1052823 Z73065.1 1-2865
1051726-1057782 Z73066.1 1-6057
1057258-1059014 Z73067.1 1-1757
1058725-1060657 Z73068.1 1-1933
1060033-1061851 Z73069.1 1-1819
1061591-1063812 Z73070.1 1-2222
1063154-1067221 Z73071.1 1-4068
1064941-1070292 Z73072.1 1-5352
1068765-1073962 Z73073.1 1-5198
1071715-1076282 Z73074.1 1-4568
1075926-1076598 Z73076.1 1-673
1076505-1079884 Z73077.1 1-3380
1078354-1081583 Z73078.1 1-3230
1080669-1084863 Z73080.1 1-4195
1082730-1090940 Z73081.1 1-8211
FEATURES Location/Qualifiers
source 1..1090940
/organism="Saccharomyces cerevisiae S288c"
/mol_type="genomic DNA"
/strain="S288c"
/db_xref="taxon:559292"
/chromosome="VII"
telomere complement(1..781)
/note="TEL07L; Telomeric region on the left arm of
Chromosome VII; composed of an X element core sequence, X
element combinatorial repeats, and a short terminal
stretch of telomeric repeats"
/db_xref="SGD:S000028887"
repeat_region complement(1..34)
/note="TEL07L-TR; Terminal stretch of telomeric repeats on
the left arm of Chromosome VII"
/rpt_family="Telomeric Repeat"
/db_xref="SGD:S000028888"
repeat_region complement(35..317)
/note="TEL07L-XR; Telomeric X element combinatorial Repeat
region on the left arm of Chromosome VII; contains repeats
of the D, C, B and A types, as well as Tbf1p binding
sites; formerly called SubTelomeric Repeats"
/rpt_family="X element Combinatorial Repeats"
/db_xref="SGD:S000028890"
repeat_region complement(318..781)
/note="TEL07L-XC; Telomeric X element Core sequence on the
left arm of Chromosome VII, contains an ARS consensus
sequence and an Abf1p binding site consensus sequence"
/rpt_family="X element Core sequence"
/db_xref="SGD:S000028889"
LTR 838..1079
/note="Ty5 LTR"
/db_xref="SGD:S000006948"
gene 2790..3932
/gene="COS12"
/locus_tag="YGL263W"
/db_xref="GeneID:852628"
mRNA 2790..3932
/gene="COS12"
/locus_tag="YGL263W"
/product="Cos12p"
/transcript_id="NM_001181129.1"
/db_xref="GI:296144795"
/db_xref="GeneID:852628"
CDS 2790..3932
/gene="COS12"
/locus_tag="YGL263W"
/note="hypothetical protein, member of the DUP380
subfamily of conserved, often subtelomerically-encoded
proteins"
/codon_start=1
/product="Cos12p"
/protein_id="NP_011251.1"
/db_xref="GI:6321174"
/db_xref="SGD:S000003232"
/db_xref="GeneID:852628"
/translation="MDGAKFENTVAFLPSEIFDCYNSTLPKNVFRSFVTWSCYEKFNS
LEFRTWLLMWLPLIIAWKIRGKRHYLVIVTALMFEVLYFLWTYSYIFRERTLGKQVSQ
FAKEIITNTPGIDTEDWERVAVNFNSYLYENKLWNTEYFFFDGSSCQEAFRKMLLEPF
SLKKNDFANAKVPDGSVCYTEKALQVYFTQIERKWHWINSEGFLHNKTTQSVQFSKHG
YGSKLLWAFKEVTIMNSRFAFFSIAYLNGLLTIPRLRNSLHILYVCAVLSSMIIEYLI
GIDKFRFKSMNLIHKLQFLSYITCGHEKSDATNWSQIAKRTNTYMFEQKIWNSPILFS
DGIDCEKFFKWYFSTPVSSQASLSVGSTDFELWPYIKEAQSACNDV"
gene 5312..5839
/locus_tag="YGL262W"
/db_xref="GeneID:852629"
mRNA 5312..5839
/locus_tag="YGL262W"
/product="hypothetical protein"
/transcript_id="NM_001181128.1"
/db_xref="GI:296144796"
/db_xref="GeneID:852629"
CDS 5312..5839
/locus_tag="YGL262W"
/note="hypothetical protein; null mutant displays elevated
sensitivity to expression of a mutant huntingtin fragment
or of alpha-synuclein; YGL262W is not an essential gene"
/codon_start=1
/product="hypothetical protein"
/protein_id="NP_011252.1"
/db_xref="GI:6321175"
/db_xref="SGD:S000003231"
/db_xref="GeneID:852629"
/translation="MRNNVTELVNSIIGVQTPGSLPDTLSGAHSLQRRISYFDVNWIS
WNWDNVNVDLNKEVKKSRPLLGEEDDQCMFGWFANNPGWKYYWSVTDNPDPGYKENYS
DIGDENAVHGELYFNTYGGLMASVMTTKMVLNAKRQLVVIDTIVVKAICDYVMKYWKK
KVNLTTISLYLMLKL"
gene complement(6290..6652)
/gene="PAU11"
/locus_tag="YGL261C"
/db_xref="GeneID:852630"
mRNA complement(6290..6652)
/gene="PAU11"
/locus_tag="YGL261C"
/product="Pau11p"
/transcript_id="NM_001181127.1"
/db_xref="GI:296144797"
/db_xref="GeneID:852630"
CDS complement(6290..6652)
/gene="PAU11"
/locus_tag="YGL261C"
/note="hypothetical protein and member of the seripauperin
multigene family encoded mainly in subtelomeric regions;
mRNA expression appears to be regulated by SUT1 and UPC2"
/codon_start=1
/product="Pau11p"
/protein_id="NP_011253.1"
/db_xref="GI:6321176"
/db_xref="SGD:S000003230"
/db_xref="GeneID:852630"
/translation="MVKLTSIAAGVAAIAATASATTTLAQSDERVNLVELGVYVSDIR
AHLAQYYMFQAAHPTETYPVEVAEAVFNYGDFTTMLTGIAPDQVTRMITGVPWYSSRL
KPAISSALSKDGIYTIAN"
gene 6860..7090
/locus_tag="YGL260W"
/db_xref="GeneID:852631"
mRNA 6860..7090
/locus_tag="YGL260W"
/product="hypothetical protein"
/transcript_id="NM_001181126.1"
/db_xref="GI:296144798"
/db_xref="GeneID:852631"
CDS 6860..7090
/locus_tag="YGL260W"
/note="hypothetical protein; transcription is
significantly increased in a NAP1 deletion background;
deletion mutant has increased accumulation of nickel and
selenium"
/codon_start=1
/product="hypothetical protein"
/protein_id="NP_011254.1"
/db_xref="GI:6321177"
/db_xref="SGD:S000003229"
/db_xref="GeneID:852631"
/translation="MEMLLFLNESYIFHRLRMWSIVLWHSCVFVCAECGNANYRVPRC
LIKPFSVPVTFPFSVKKNIRILDLDPRTEAYC"
gene 8470..8967
/gene="YPS5"
/locus_tag="YGL259W"
/db_xref="GeneID:852632"
mRNA 8470..8967
/gene="YPS5"
/locus_tag="YGL259W"
/product="Yps5p"
/transcript_id="NM_001181125.1"
/db_xref="GI:296144799"
/db_xref="GeneID:852632"
CDS 8470..8967
/gene="YPS5"
/locus_tag="YGL259W"
/note="Protein with similarity to GPI-anchored aspartic
proteases such as Yap1p and Yap3p"
/codon_start=1
/product="Yps5p"
/protein_id="NP_011255.1"
/db_xref="GI:6321178"
/db_xref="SGD:S000003228"
/db_xref="GeneID:852632"
/translation="MQLFSILSLLSSLMCSLTVLGSSASSYVKFPVQKFADIINIGTQ
DVSTVFKRNEVLNTTVINGIGVYVVKMEIGTPPQTVYLQLDTGSSDMIVNNADIAYCK
SMSDGSDYASTDNYELTATFTGPRSTTTSPELITLSALIGVNSMQETHLLLRITRLSS
MTYTY"
gene 9162..9395
/locus_tag="YGL258W-A"
/db_xref="GeneID:852633"
mRNA 9162..9395
/locus_tag="YGL258W-A"
/product="hypothetical protein"
/transcript_id="NM_001184473.1"
/db_xref="GI:296144800"
/db_xref="GeneID:852633"
CDS 9162..9395
/locus_tag="YGL258W-A"
/codon_start=1
/product="hypothetical protein"
/protein_id="NP_076890.1"
/db_xref="GI:13129168"
/db_xref="SGD:S000007607"
/db_xref="GeneID:852633"
/translation="MAFERQGKIEKKISYSLFLNGPNVHFGSILFGAVDKSKYAEELC
THPMRQAYNTLDSNSRIIITVQSVAILDGKLVW"
gene 11110..11730
/gene="VEL1"
/locus_tag="YGL258W"
/db_xref="GeneID:852634"
mRNA 11110..11730
/gene="VEL1"
/locus_tag="YGL258W"
/product="Vel1p"
/transcript_id="NM_001181124.1"
/db_xref="GI:296144801"
/db_xref="GeneID:852634"
CDS 11110..11730
/gene="VEL1"
/locus_tag="YGL258W"
/note="hypothetical protein; highly induced in
zinc-depleted conditions and has increased expression in
NAP1 deletion mutants"
/codon_start=1
/product="Vel1p"
/protein_id="NP_011256.1"
/db_xref="GI:6321179"
/db_xref="SGD:S000003227"
/db_xref="GeneID:852634"
/translation="MSFLSIFTFFSVLISVATTVRFDLTNVTCKGLHGPHCGTYVMEV
VGQNGTFLGQSTFVGADVLTESAGDAWARYLGQETRFLPKLTTIASNETKNFSPLIFT
TNINTCNPQSIGDAMVPFANTVTGEIEYNSWADTADNASFITGLANQLFNSTDYGVQV
ASCYPNFASVILSTPAVNIFGKDDTLPDYCTAIQLKAVCPPEAGFD"
gene complement(12481..14157)
/gene="MNT2"
/locus_tag="YGL257C"
/db_xref="GeneID:852635"
mRNA complement(12481..14157)
/gene="MNT2"
/locus_tag="YGL257C"
/product="Mnt2p"
/transcript_id="NM_001181123.1"
/db_xref="GI:296144802"
/db_xref="GeneID:852635"
CDS complement(12481..14157)
/gene="MNT2"
/locus_tag="YGL257C"
/EC_number="2.4.1.-"
/note="Mannosyltransferase involved in adding the 4th and
5th mannose residues of O-linked glycans"
/codon_start=1
/product="Mnt2p"
/protein_id="NP_011257.1"
/db_xref="GI:6321180"
/db_xref="SGD:S000003226"
/db_xref="GeneID:852635"
/translation="MRRKNRLFILVVLLGIVLVVYYSQLNSLDLVEPVQSSSSGNGGC
WSYYEGLTPGWLNDFYDVNQITPNPAKDVIELVTRIKIFFNCLQQVDGHNIQRLRDIE
KKLFPYINFEKLETDESAFWHTTTRWNGEVYHASMLEFDPKNHQFLRSKPINFDTGLS
FWENWLHTVTQSGSKGIVISASDVQLNETIRLLKVLRFIKNDYPIQIVHNADLSQDSM
KSIIKYARSLDTAEYPAQELWFLNVHSLLNPKYSKKFTTYSNKWLALTFSSFEIPILM
DSDTVPFVSIEKFYELEEFQKTGVLFFKDRVISDDLFESSELKILREIVYGCIGLDLE
DESKIHEQVEDPVVAQVLENMFIKKYKHHLESGLVILHKGKHLFSMLTSIALQFSPIA
EYFHGDKDFFWLGELLSNNRFTFHPVDASNIGQLGNVVSKESTGEFYQICSVQLSHTD
RDGSLLWLNGGLNICKKTSWEYDYEHRQRLNDMFQNADELREYYASPVKLEGIIIPDT
SISGWINSGECFLFNYCTLFKEGEFGKLIKFKEDEKLRLSQIVDIWNKDI"
gene 15159..16307
/gene="ADH4"
/locus_tag="YGL256W"
/gene_synonym="NRC465; ZRG5"
/db_xref="GeneID:852636"
mRNA 15159..16307
/gene="ADH4"
/locus_tag="YGL256W"
/gene_synonym="NRC465; ZRG5"
/product="alcohol dehydrogenase ADH4"
/transcript_id="NM_001181122.1"
/db_xref="GI:296144803"
/db_xref="GeneID:852636"
CDS 15159..16307
/gene="ADH4"
/locus_tag="YGL256W"
/gene_synonym="NRC465; ZRG5"
/EC_number="1.1.1.190"
/EC_number="1.1.1.1"
/note="Alcohol dehydrogenase isoenzyme type IV, dimeric
enzyme demonstrated to be zinc-dependent despite sequence
similarity to iron-activated alcohol dehydrogenases;
transcription is induced in response to zinc deficiency"
/codon_start=1
/product="alcohol dehydrogenase ADH4"
/protein_id="NP_011258.2"
/db_xref="GI:269970305"
/db_xref="SGD:S000003225"
/db_xref="GeneID:852636"
/translation="MSSVTGFYIPPISFFGEGALEETADYIKNKDYKKALIVTDPGIA
AIGLSGRVQKMLEERDLNVAIYDKTQPNPNIANVTAGLKVLKEQNSEIVVSIGGGSAH
DNAKAIALLATNGGEIGDYEGVNQSKKAALPLFAINTTAGTASEMTRFTIISNEEKKI
KMAIIDNNVTPAVAVNDPSTMFGLPPALTAATGLDALTHCIEAYVSTASNPITDACAL
KGIDLINESLVAAYKDGKDKKARTDMCYAEYLAGMAFNNASLGYVHALAHQLGGFYHL
PHGVCNAVLLPHVQEANMQCPKAKKRLGEIALHFGASQEDPEETIKALHVLNRTMNIP
RNLKELGVKTEDFEILAEHAMHDACHLTNPVQFTKEQVVAIIKKAYEY"
gene 20978..22108
/gene="ZRT1"
/locus_tag="YGL255W"
/db_xref="GeneID:852637"
mRNA 20978..22108
/gene="ZRT1"
/locus_tag="YGL255W"
/product="high-affinity Zn(2+) transporter ZRT1"
/transcript_id="NM_001181121.1"
/db_xref="GI:296144804"
/db_xref="GeneID:852637"
CDS 20978..22108
/gene="ZRT1"
/locus_tag="YGL255W"
/note="High-affinity zinc transporter of the plasma
membrane, responsible for the majority of zinc uptake;
transcription is induced under low-zinc conditions by the
Zap1p transcription factor"
/codon_start=1
/product="high-affinity Zn(2+) transporter ZRT1"
/protein_id="NP_011259.1"
/db_xref="GI:6321182"
/db_xref="SGD:S000003224"
/db_xref="GeneID:852637"
/translation="MSNVTTPWWKQWDPSEVTLADKTPDDVWKTCVLQGVYFGGNEYN
GNLGARISSVFVILFVSTFFTMFPLISTKVKRLRIPLYVYLFAKYFGSGVIVATAFIH
LMDPAYGAIGGTTCVGQTGNWGLYSWCPAIMLTSLTFTFLTDLFSSVWVERKYGLSHD
HTHDEIKDTVVRNTAAVSSENDNENGTANGSHDTKNGVEYYEDSDATSMDVVQSFQAQ
FYAFLILEFGVIFHSVMIGLNLGSVGDEFSSLYPVLVFHQSFEGLGIGARLSAIEFPR
SKRWWPWALCVAYGLTTPICVAIGLGVRTRYVSGSYTALVISGVLDAISAGILLYTGL
VELLARDFIFNPQRTKDLRELSFNVICTLFGAGIMALIGKWA"
gene 22304..23203
/gene="FZF1"
/locus_tag="YGL254W"
/gene_synonym="NRC299; RSU1; SUL1"
/db_xref="GeneID:852638"
mRNA 22304..23203
/gene="FZF1"
/locus_tag="YGL254W"
/gene_synonym="NRC299; RSU1; SUL1"
/product="Fzf1p"
/transcript_id="NM_001181120.1"
/db_xref="GI:296144805"
/db_xref="GeneID:852638"
CDS 22304..23203
/gene="FZF1"
/locus_tag="YGL254W"
/gene_synonym="NRC299; RSU1; SUL1"
/note="Transcription factor involved in sulfite
metabolism; sole identified regulatory target is SSU1;
overexpression suppresses sulfite-sensitivity of many
unrelated mutants due to hyperactivation of SSU1, contains
five zinc fingers; protein abundance increases in response
to DNA replication stress"
/codon_start=1
/product="Fzf1p"
/protein_id="NP_011260.1"
/db_xref="GI:6321183"
/db_xref="SGD:S000003223"
/db_xref="GeneID:852638"
/translation="MTDIGRTKSRNYKCSFDGCEKVYNRPSLLQQHQNSHTNQKPYHC
DEPGCGKKFIRPCHLRVHKWTHSQIKPKACTLCQKRFVTNQQLRRHLNSHERKSKLAS
RIDRKHEGVNANVKAELNGKEGGFDPKLPSGSPMCGEEFSQGHLPGYDDMQVLQCPYK
SCQKVTSFNDDLINHMLQHHIASKLVVPSGDPSLKESLPTSEKSSSTDTTSIPQLSFS
TTGTSSSESVDSTTAQTPTDPESYWSDNRCKHSDCQELSPFASVFDLIDHYDHTHAFI
PETLVKYSYIHLYKPSVWDLFEY"
gene 23935..25395
/gene="HXK2"
/locus_tag="YGL253W"
/gene_synonym="HEX1; HKB; SCI2"
/db_xref="GeneID:852639"
mRNA 23935..25395
/gene="HXK2"
/locus_tag="YGL253W"
/gene_synonym="HEX1; HKB; SCI2"
/product="hexokinase 2"
/transcript_id="NM_001181119.1"
/db_xref="GI:296144806"
/db_xref="GeneID:852639"
CDS 23935..25395
/gene="HXK2"
/locus_tag="YGL253W"
/gene_synonym="HEX1; HKB; SCI2"
/EC_number="2.7.1.4"
/EC_number="2.7.1.1"
/note="Hexokinase isoenzyme 2; catalyzes phosphorylation
of glucose in the cytosol; predominant hexokinase during
growth on glucose; functions in the nucleus to repress
expression of HXK1 and GLK1 and to induce expression of
its own gene; phosphorylation/dephosphorylation at
serine-14 by protein kinase Snf1p and protein phosphatase
Glc7p-Reg1p regulates nucleocytoplasmic shuttling of
Hxk2p; HXK2 has a paralog, HXK1, that arose from the whole
genome duplication"
/codon_start=1
/product="hexokinase 2"
/protein_id="NP_011261.1"
/db_xref="GI:6321184"
/db_xref="SGD:S000003222"
/db_xref="GeneID:852639"
/translation="MVHLGPKKPQARKGSMADVPKELMQQIENFEKIFTVPTETLQAV
TKHFISELEKGLSKKGGNIPMIPGWVMDFPTGKESGDFLAIDLGGTNLRVVLVKLGGD
RTFDTTQSKYRLPDAMRTTQNPDELWEFIADSLKAFIDEQFPQGISEPIPLGFTFSFP
ASQNKINEGILQRWTKGFDIPNIENHDVVPMLQKQITKRNIPIEVVALINDTTGTLVA
SYYTDPETKMGVIFGTGVNGAYYDVCSDIEKLQGKLSDDIPPSAPMAINCEYGSFDNE
HVVLPRTKYDITIDEESPRPGQQTFEKMSSGYYLGEILRLALMDMYKQGFIFKNQDLS
KFDKPFVMDTSYPARIEEDPFENLEDTDDLFQNEFGINTTVQERKLIRRLSELIGARA
ARLSVCGIAAICQKRGYKTGHIAADGSVYNRYPGFKEKAANALKDIYGWTQTSLDDYP
IKIVPAEDGSGAGAAVIAALAQKRIAEGKSVGIIGA"
gene complement(25718..27484)
/gene="RTG2"
/locus_tag="YGL252C"
/db_xref="GeneID:852640"
mRNA complement(25718..27484)
/gene="RTG2"
/locus_tag="YGL252C"
/product="Rtg2p"
/transcript_id="NM_001181118.1"
/db_xref="GI:296144807"
/db_xref="GeneID:852640"
CDS complement(25718..27484)
/gene="RTG2"
/locus_tag="YGL252C"
/note="Sensor of mitochondrial dysfunction; regulates the
subcellular location of Rtg1p and Rtg3p, transcriptional
activators of the retrograde (RTG) and TOR pathways; Rtg2p
is inhibited by the phosphorylated form of Mks1p"
/codon_start=1
/product="Rtg2p"
/protein_id="NP_011262.1"
/db_xref="GI:6321185"
/db_xref="SGD:S000003221"
/db_xref="GeneID:852640"
/translation="MSTLSDSDTETEVVSRNLCGIVDIGSNGIRFSISSKAAHHARIM
PCVFKDRVGLSLYEVQYNTHTNAKCPIPRDIIKEVCSAMKRFKLICDDFGVPETSVRV
IATEATRDAINADEFVNAVYGSTGWKVEILGQEDETRVGIYGVVSSFNTVRGLYLDVA
GGSTQLSWVISSHGEVKQSSKPVSLPYGAGTLLRRMRTDDNRALFYEIKEAYKDAIEK
IGIPQEMIDDAKKEGGFDLWTRGGGLRGMGHLLLYQSEGYPIQTIINGYACTYEEFSS
MSDYLFLKQKIPGSSKEHKIFKVSDRRALQLPAVGLFMSAVFEAIPQIKAVHFSEGGV
REGSLYSLLPKEIRAQDPLLIASRPYAPLLTEKYLYLLRTSIPQEDIPEIVNERIAPA
LCNLAFVHASYPKELQPTAALHVATRGIIAGCHGLSHRARALIGIALCSRWGGNIPES
EEKYSQELEQVVLREGDKAEALRIVWWTKYIGTIMYVICGVHPGGNIRDNVFDFHVSK
RSEVETSLKELIIDDANTTKVKEESTRKNRGYEVVVRISKDDLKTSASVRSRIITLQK
KVRKLSRGSVERVKIGVQFYEE"
gene complement(27921..31636)
/gene="HFM1"
/locus_tag="YGL251C"
/gene_synonym="MER3"
/db_xref="GeneID:852641"
mRNA complement(join(27921..31426,31579..31636))
/gene="HFM1"
/locus_tag="YGL251C"
/gene_synonym="MER3"
/product="Hfm1p"
/transcript_id="NM_001181117.1"
/db_xref="GI:296144808"
/db_xref="GeneID:852641"
CDS complement(join(27921..31426,31579..31636))
/gene="HFM1"
/locus_tag="YGL251C"
/gene_synonym="MER3"
/EC_number="3.6.1.-"
/note="Meiosis specific DNA helicase involved in the
conversion of double-stranded breaks to later
recombination intermediates and in crossover control;
catalyzes the unwinding of Holliday junctions; has ssDNA
and dsDNA stimulated ATPase activity"
/codon_start=1
/product="Hfm1p"
/protein_id="NP_011263.2"
/db_xref="GI:9755332"
/db_xref="SGD:S000003220"
/db_xref="GeneID:852641"
/translation="MKTKFDRLGTGKRSRPSPNNIDFNDQSATFKRNKKNSRQPSFKV
GLSYNSLLDDCDDENETEEIFEGRGLQFFDKDDNFSITADDTQVTSKLFDHDLEQTPD
EEAKKPKKVTIRKSAKKCLSTTILPDSFRGVFKFTEFNKMQSEAFPSIYESNENCIIS
SPTGSGKTVLFELAILRLIKETNSDTNNTKIIYIAPTKSLCYEMYKNWFPSFVNLSVG
MLTSDTSFLETEKAKKCNIIITTPEKWDLLTRRWSDYSRLFELVKLVLVDEIHTIKEK
RGASLEVILTRMNTMCQNIRFVALSATVPNIEDLALWLKTNNELPANILSFDESYRQV
QLTKFVYGYSFNCKNDFQKDAIYNSKLIEIIEKHADNRPVLIFCPTRASTISTAKFLL
NNHIFSKSKKRCNHNPSDKILNECMQQGIAFHHAGISLEDRTAVEKEFLAGSINILCS
TSTLAVGVNLPAYLVIIKGTKSWNSSEIQEYSDLDVLQMIGRAGRPQFETHGCAVIMT
DSKMKQTYENLIHGTDVLESSLHLNLIEHLAAETSLETVYSIETAVNWLRNTFFYVRF
GKNPAAYQEVNRYVSFHSVEDSQINQFCQYLLDTLVKVKIIDISNGEYKSTAYGNAMT
RHYISFESMKQFINAKKFLSLQGILNLLATSEEFSVMRVRHNEKKLFKEINLSPLLKY
PFLTEKKQSQIIDRVSQKVSLLIQYELGGLEFPSYEGASKLHQTLVQDKFLVFRHCFR
LLKCMVDTFIEKSDGTSLKNTLFLLRSLNGHCWENTPMVLRQLKTIGLVSVRRLIRHG
ITNLEEMGHLSDTQIEYYLNLKIGNGIKIKNDISLLPCLNIRTKLENCKIENEELWLT
FKVEISATFKSSIWHGQHLSLDIETEKSSGELIDFRRLQVNKLQSPRGFRISAKISPK
LEKIEFSIHCQEIAGLGKTIVYSTDHLASQFSAKTPNIRKDLNSLEKCLFYESSSDGE
VGKTSRVSHKDGLEESLSSDDSILDYLNERKKSSKAVESAAVIHPEAHSSSHFSNGRQ
VRSNGNYECFHSCKDKTQCRHLCCKEGIPVKYIKEKGPSSIKPVSKPDQIRQPLLAKN
INTTPHLEKRLNSKPKQWQEENTDIATVHTLPSKIYNLSQQMSSMEAGEQVLKSGPEN
CPEIIPIDLESSDSYSSNTAASSISDPNGDLDFLGSDIEFE"
gene 31910..32635
/gene="RMR1"
/locus_tag="YGL250W"
/db_xref="GeneID:852642"
mRNA 31910..32635
/gene="RMR1"
/locus_tag="YGL250W"
/product="Rmr1p"
/transcript_id="NM_001181116.1"
/db_xref="GI:296144809"
/db_xref="GeneID:852642"
CDS 31910..32635
/gene="RMR1"
/locus_tag="YGL250W"
/note="Protein required for meiotic recombination and gene
conversion; null mutant displays reduced PIS1 expression
and growth defects on non-fermentable carbon sources and
minimal media; GFP-fusion protein localizes to both
cytoplasm and nucleus"
/codon_start=1
/product="Rmr1p"
/protein_id="NP_011264.2"
/db_xref="GI:37362648"
/db_xref="SGD:S000003219"
/db_xref="GeneID:852642"
/translation="MSEEEAHKTVEVDDVGVQLDEGDEEDLLEYDDELVEEQPSDARI
RNVAETLMKSELPKVTVEYKDTTFLLFTSDDKNESNNPIICENAALYQRPMGEFMESI
RKFMGNRFGRLAFATKELVLQLKSLDLTLFEDNVYNNHISFSDVYTIFKILKERSESN
FETDIPTHLAIELSTRPRFVSRYNALVELTESSATLKNIKPFSNDETHPLIVDDNDQY
THQNTSEVIVMDIDDDVGEDSED"
gene 33098..35212
/gene="ZIP2"
/locus_tag="YGL249W"
/db_xref="GeneID:852643"
mRNA 33098..35212
/gene="ZIP2"
/locus_tag="YGL249W"
/product="Zip2p"
/transcript_id="NM_001181115.1"
/db_xref="GI:296144810"
/db_xref="GeneID:852643"
CDS 33098..35212
/gene="ZIP2"
/locus_tag="YGL249W"
/note="Meiosis-specific protein; involved in normal
synaptonemal complex formation and pairing between
homologous chromosomes during meiosis; relocalizes from
mitochondrion to cytoplasm upon DNA replication stress"
/codon_start=1
/product="Zip2p"
/protein_id="NP_011265.1"
/db_xref="GI:6321188"
/db_xref="SGD:S000003218"
/db_xref="GeneID:852643"
/translation="MIIERWEVKLSKCNQNVGGYSVLSGNLKENIKLGRRAQKYLKEL
RNLQLKPLKIGGYENCGTINGEEYFLEVIHITSGRQKIDVAVGKTWNVTNIENDNKEE
LQYELFKEKLKVGKQDMLFFSWMKSLSVQLNAPLHQKMTEHGLADDNTRLEWFNIPLL
RRSQYRKKVPYPSLRQMSSVLEVQCSTLTEEKLNFCVGFSDKPLSEWKPQIFEQTYNR
YRLQRISPEKSFKYKSRCSKYNFKTSSQSWVVKVPEHDQQLNTFEKRYDELFDAQFNK
LEFFKIRMKKLKKNKPIEKKNYKIWCLEKEDLKDLVWDPLKRICNHSRYAIFEHVTIN
REAYSIKPLRLTFQKLDSGSLDLIDNQKKTFGSIKLAMSMPDVKKTENQSIEESERHD
ETAIETQEFDENDCLSSKADINTSLAPQKRSFIDNELMSMLVTKKKIKKDKDVSDTGI
SSTSYLINSGTYANSHIEIPTSNSVYNGKEDCSFNNYSVKHSILEEDIENKCIAVNEN
KVIENQKVIQSLCKNSHLDLIEQSYFGECDFIINHSTCVYKIQASRFMQLRNNGSLHY
DKAVNDLLTEFQRVIIIVEFSEIIQDVDPDLFWKIKLYLLNSRVDVFFIHETTDFFID
WMKYFIARWAFSYNDEKEKNIANADILLDLGFNILLVRKIFQTYSLEEFFMAIIKEES
KAVKMLTVSQMTRLKKLLTLEW"
gene 35653..36762
/gene="PDE1"
/locus_tag="YGL248W"
/db_xref="GeneID:852644"
mRNA 35653..36762
/gene="PDE1"
/locus_tag="YGL248W"
/product="Pde1p"
/transcript_id="NM_001181114.1"
/db_xref="GI:296144811"
/db_xref="GeneID:852644"
CDS 35653..36762
/gene="PDE1"
/locus_tag="YGL248W"
/EC_number="3.1.4.17"
/note="Low-affinity cyclic AMP phosphodiesterase, controls
glucose and intracellular acidification-induced cAMP
signaling, target of the cAMP-protein kinase A (PKA)
pathway; glucose induces transcription and inhibits
translation"
/codon_start=1
/product="Pde1p"
/protein_id="NP_011266.1"
/db_xref="GI:6321189"
/db_xref="SGD:S000003217"
/db_xref="GeneID:852644"
/translation="MVVFEITILGANGGPTEYGTQCFILKPARTEDPELIAVDGGAGM
YQLREMLVQGRNENEGDDELVPSFYEHDREPIEFFIDSKLNIQKGLSKSLLQSLKRQG
EHFESANTMKKTYEVFQGITDYYITHPHLDHISGLVVNSPSIYEQENSKKKTIWGLPH
TIDVLQKHVFNDLIWPDLTAERSRKLKLKCLNPKEVQKCTIFPWDVIPFKVHHGIGVK
TGAPVYSTFYIFRDRKSKDCIIVCGDVEQDRRESEESLLEEFWSYVAENIPLVHLKGI
LVECSCPLSSKPEQLYGHLSPIYLINELSNLNTLYNSSKGLSGLNVIVTHVKSTPAKR
DPRLTILEELRFLAEERNLGDLRISIALEGHTLFL"
gene 36933..37526
/gene="BRR6"
/locus_tag="YGL247W"
/db_xref="GeneID:852645"
mRNA 36933..37526
/gene="BRR6"
/locus_tag="YGL247W"
/product="Brr6p"
/transcript_id="NM_001181113.1"
/db_xref="GI:296144812"
/db_xref="GeneID:852645"
CDS 36933..37526
/gene="BRR6"
/locus_tag="YGL247W"
/note="Essential nuclear envelope integral membrane
protein required for nuclear envelope morphology, nuclear
pore complex localization, nuclear export; exhibits
synthetic lethal genetic interactions with genes involved
in lipid metabolism"
/codon_start=1
/product="Brr6p"
/protein_id="NP_011267.1"
/db_xref="GI:6321190"
/db_xref="SGD:S000003216"
/db_xref="GeneID:852645"
/translation="MELRSFSRQPDGILANPRLGREEVLEGEHPQDARLARQSIWLSP
SLIAEYIQLFFNFIIGTIGLSLAIKFILMIRNDVNLKLEHNVREELDKIATCKSRYFE
NQCEPHMRVPALEVRCNEWSKCMNKEIVSGSDYQWAKAWARTLAEVINAFFEAFSIRS
FLFILISIIGIIFVTNTSFGSYRVYLNNKDTKSVRHA"
gene complement(37617..38780)
/gene="RAI1"
/locus_tag="YGL246C"
/db_xref="GeneID:852646"
mRNA complement(37617..38780)
/gene="RAI1"
/locus_tag="YGL246C"
/product="Rai1p"
/transcript_id="NM_001181112.1"
/db_xref="GI:296144813"
/db_xref="GeneID:852646"
CDS complement(37617..38780)
/gene="RAI1"
/locus_tag="YGL246C"
/note="Nuclear protein with decapping endonuclease
activity targeted toward mRNAs with unmethylated
7-methylguanosine cap structures; binds to and stabilizes
the exoribonuclease Rat1p; required for pre-rRNA
processing; homologous to human DOM3Z"
/codon_start=1
/product="Rai1p"
/protein_id="NP_011268.1"
/db_xref="GI:6321191"
/db_xref="SGD:S000003215"
/db_xref="GeneID:852646"
/translation="MGVSANLFVKQRGSTTALKQPKEIGFYSRTKDEEYLISDDTNLN
YYYLPDAELDRKLDLSSGFQKFKDYYKDFEDRCSLRGLLETIESSERHKGKKINADII
TFRGIARKLISCAFDSPSFNTVDLRIVSFNGQLFIKEVPEAVNAAKASSATEAGRNIN
QDLNVFTGYKFETLATLSNPLQYTPREVIEKRTKRIVSHGDEYISVVRTGVGNCKLIL
GAEVDCIFDFKENGRDNLKHYAELKCTQQVANISDTHKFERKLFRTWLQCFLVGIPRI
IYGFKDDHYVLKTVEEFSTEEVPVLLKNNNPQVGSACLEAIKWYGLLTEWLLKMIPRD
EDPHSQIRAFKLVFENNHLRLSEIEESDEEYSGLIDGEHILSNGFKEWRKSLK"
gene 39023..41149
/gene="GUS1"
/locus_tag="YGL245W"
/gene_synonym="GSN1"
/db_xref="GeneID:852606"
mRNA 39023..41149
/gene="GUS1"
/locus_tag="YGL245W"
/gene_synonym="GSN1"
/product="glutamate--tRNA ligase GUS1"
/transcript_id="NM_001181111.1"
/db_xref="GI:296144814"
/db_xref="GeneID:852606"
CDS 39023..41149
/gene="GUS1"
/locus_tag="YGL245W"
/gene_synonym="GSN1"
/EC_number="6.1.1.17"
/note="Glutamyl-tRNA synthetase (GluRS); forms a complex
with methionyl-tRNA synthetase (Mes1p) and Arc1p; complex
formation increases the catalytic efficiency of both tRNA
synthetases and ensures their correct localization to the
cytoplasm; protein abundance increases in response to DNA
replication stress"
/codon_start=1
/product="glutamate--tRNA ligase GUS1"
/protein_id="NP_011269.2"
/db_xref="GI:37362649"
/db_xref="SGD:S000003214"
/db_xref="GeneID:852606"
/translation="MPSTLTINGKAPIVAYAELIAARIVNALAPNSIAIKLVDDKKAP
AAKLDDATEDVFNKITSKFAAIFDNGDKEQVAKWVNLAQKELVIKNFAKLSQSLETLD
SQLNLRTFILGGLKYSAADVACWGALRSNGMCGSIIKNKVDVNVSRWYTLLEMDPIFG
EAHDFLSKSLLELKKSANVGKKKETHKANFEIDLPDAKMGEVVTRFPPEPSGYLHIGH
AKAALLNQYFAQAYKGKLIIRFDDTNPSKEKEEFQDSILEDLDLLGIKGDRITYSSDY
FQEMYDYCVQMIKDGKAYCDDTPTEKMREERMDGVASARRDRSVEENLRIFTEEMKNG
TEEGLKNCVRAKIDYKALNKTLRDPVIYRCNLTPHHRTGSTWKIYPTYDFCVPIVDAI
EGVTHALRTIEYRDRNAQYDWMLQALRLRKVHIWDFARINFVRTLLSKRKLQWMVDKD
LVGNWDDPRFPTVRGVRRRGMTVEGLRNFVLSQGPSRNVINLEWNLIWAFNKKVIDPI
APRHTAIVNPVKIHLEGSEAPQEPKIEMKPKHKKNPAVGEKKVIYYKDIVVDKDDADV
INVDEEVTLMDWGNVIITKKNDDGSMVAKLNLEGDFKKTKHKLTWLADTKDVVPVDLV
DFDHLITKDRLEEDESFEDFLTPQTEFHTDAIADLNVKDMKIGDIIQFERKGYYRLDA
LPKDGKPYVFFTIPDGKSVNKYGAKK"
gene 41498..43174
/gene="RTF1"
/locus_tag="YGL244W"
/gene_synonym="CSL3"
/db_xref="GeneID:852607"
mRNA 41498..43174
/gene="RTF1"
/locus_tag="YGL244W"
/gene_synonym="CSL3"
/product="Rtf1p"
/transcript_id="NM_001181110.1"
/db_xref="GI:296144815"
/db_xref="GeneID:852607"
CDS 41498..43174
/gene="RTF1"
/locus_tag="YGL244W"
/gene_synonym="CSL3"
/note="Subunit of RNAPII-associated chromatin remodeling
Paf1 complex; regulates gene expression by directing
cotranscriptional histone modification, influences
transcription and chromatin structure through several
independent functional domains; directly or indirectly
regulates DNA-binding properties of Spt15p and relative
activities of different TATA elements; involved in
transcription elongation as demonstrated by the
G-less-based run-on (GLRO) assay"
/codon_start=1
/product="Rtf1p"
/protein_id="NP_011270.1"
/db_xref="GI:6321193"
/db_xref="SGD:S000003213"
/db_xref="GeneID:852607"
/translation="MSDLDEDLLALAGADESEEEDQVLTTTSAKRAKNNDQSLSKKRR
IEVGSVEDDDEEDDYNPYSVGNADYGSEEEEEANPFPLEGKYKDESDREHLESLPEME
RETLLFERSQIMQKYQERKLFRARGRDMKEQQQRAKNDEDSRKTRASTRSTHATGHSD
IKASKLSQLKKQRARKNRHYSDNEDEDDEEDYREEDYKDDEGSEYGDDEEYNPFDRRD
TYDKREEVEWAEEEDEQDREPEISDFNKLRIGRSFVAKFCFYPGFEDAVKGCYGRVNV
GTDKRTGKTSYRMVRIERVFLQKPYNMGKFYTNQYFGVTQGKDRKVFQMNYFSDGLFA
EDEYQRYLRALDNSQMIKPSLHSLSNKTKEVMDFVNTPLTDKTTDEVVRHRMQFNKKL
SGTNAVLEKTVLREKLQYAKETNNEKDIAKYSAQLRNFEKRMSVYEKHHENDQSDIKK
LGELTSKNRKLNMSNIRNAEHVKKEDSNNFDSKSDPFSRLKTRTKVYYQEIQKEENAK
AKEIAQQEKLQEDKDAKDKREKELLVAQFRRLGGLERMVGELDIKFDLKF"
gene 43307..44509
/gene="TAD1"
/locus_tag="YGL243W"
/db_xref="GeneID:852608"
mRNA 43307..44509
/gene="TAD1"
/locus_tag="YGL243W"
/product="Tad1p"
/transcript_id="NM_001181109.1"
/db_xref="GI:296144816"
/db_xref="GeneID:852608"
CDS 43307..44509
/gene="TAD1"
/locus_tag="YGL243W"
/EC_number="3.5.4.4"
/note="tRNA-specific adenosine deaminase, deaminates
adenosine-37 to inosine in tRNA-Ala"
/codon_start=1
/product="Tad1p"
/protein_id="NP_011271.1"
/db_xref="GI:6321194"
/db_xref="SGD:S000003212"
/db_xref="GeneID:852608"
/translation="MVSCQGTRPCIVNLLTMPSEDKLGEEISTRVINEYSKLKSACRP
IIRPSGIREWTILAGVAAINRDGGANKIEILSIATGVKALPDSELQRSEGKILHDCHA
EILALRGANTVLLNRIQNYNPSSGDKFIQHNDEIPARFNLKENWELALYISRLPCGDA
SMSFLNDNCKNDDFIKIEDSDEFQYVDRSVKTILRGRLNFNRRNVVRTKPGRYDSNIT
LSKSCSDKLLMKQRSSVLNCLNYELFEKPVFLKYIVIPNLEDETKHHLEQSFHTRLPN
LDNEIKFLNCLKPFYDDKLDEEDVPGLMCSVKLFMDDFSTEEAILNGVRNGFYTKSSK
PLRKHCQSQVSRFAQWELFKKIRPEYEGISYLEFKSRQKKRSQLIIAIKNILSPDGWI
PTRTDDVK"
gene complement(44652..45197)
/locus_tag="YGL242C"
/db_xref="GeneID:852609"
mRNA complement(44652..45197)
/locus_tag="YGL242C"
/product="hypothetical protein"
/transcript_id="NM_001181108.1"
/db_xref="GI:296144817"
/db_xref="GeneID:852609"
CDS complement(44652..45197)
/locus_tag="YGL242C"
/note="hypothetical protein; deletion mutant is viable"
/codon_start=1
/product="hypothetical protein"
/protein_id="NP_011272.1"
/db_xref="GI:6321195"
/db_xref="SGD:S000003211"
/db_xref="GeneID:852609"
/translation="MNTEGASLSEQLLDAARRNNLDLLETVFDSLDNDPEKIAKLINE
SKEPLGNTALHLCCKYGSWEVLDKILDQDGEIEIDPQNDVDGDTPLHVTVRYSQEEPE
HGTFIARNLIEVGADPRVRNYNNQKPVDLVHGDELDELIDLLQGAELAIDSTNGSGDN
NEDGEMIDDGPSDDDEEDDKK"
gene 45445..48459
/gene="KAP114"
/locus_tag="YGL241W"
/db_xref="GeneID:852610"
mRNA 45445..48459
/gene="KAP114"
/locus_tag="YGL241W"
/product="Kap114p"
/transcript_id="NM_001181107.1"
/db_xref="GI:296144818"
/db_xref="GeneID:852610"
CDS 45445..48459
/gene="KAP114"
/locus_tag="YGL241W"
/note="Karyopherin, responsible for nuclear import of
specific proteins; cargoes include Spt15p, Sua7p, histones
H2A and H2B, and Nap1p; amino terminus shows similarity to
those of other importins, particularly Cse1p; localization
is primarily nuclear; function is regulated by
sumoylation; protein abundance increases in response to
DNA replication stress"
/codon_start=1
/product="Kap114p"
/protein_id="NP_011273.1"
/db_xref="GI:6321196"
/db_xref="SGD:S000003210"
/db_xref="GeneID:852610"
/translation="MDINELIIGAQSADKHTREVAETQLLQWCDSDASQVFKALANVA
LQHEASLESRQFALLSLRKLITMYWSPGFESYRSTSNVEIDVKDFIREVLLKLCLNDN
ENTKIKNGASYCIVQISAVDFPDQWPQLLTVIYDAISHQHSLNAMSLLNEIYDDVVSE
EMFFEGGIGLATMEIVFKVLNTETSTLIAKIAALKLLKACLLQMSSHNEYDEASRKSF
VSQCLATSLQILGQLLTLNFGNVDVISQLKFKSIIYENLVFIKNDFSRKHFSSELQKQ
FKIMAIQDLENVTHINANVETTESEPLLETVHDCSIYIVEFLTSVCTLQFSVEEMNKI
ITSLTILCQLSSETREIWTSDFNTFVSKETGLAASYNVRDQANEFFTSLPNPQLSLIF
KVVSNDIEHSTCNYSTLESLLYLLQCILLNDDEITGENIDQSLQILIKTLENILVSQE
IPELILARAILTIPRVLDKFIDALPDIKPLTSAFLAKSLNLALKSDKELIKSATLIAF
TYYCYFAELDSVLGPEVCSETQEKVIRIINQVSSDAEEDTNGALMEVLSQVISYNPKE
PHSRKEILQAEFHLVFTISSEDPANVQVVVQSQECLEKLLDNINMDNYKNYIELCLPS
FINVLDSNNANNYRYSPLLSLVLEFITVFLKKKPNDGFLPDEINQYLFEPLAKVLAFS
TEDETLQLATEAFSYLIFNTDTRAMEPRLMDIMKVLERLLSLEVSDSAAMNVGPLVVA
IFTRFSKEIQPLIGRILEAVVVRLIKTQNISTEQNLLSVLCFLTCNDPKQTVDFLSSF
QIDNTDALTLVMRKWIEAFEVIRGEKRIKENIVALSNLFFLNDKRLQKVVVNGNLIPY
EGDLIITRSMAKKMPDRYVQVPLYTKIIKLFVSELSFQSKQPNPEQLITSDIKQEVVN
ANKDDDNDDWEDVDDVLDYDKLKEYIDDDVDEEADDDSDDITGLMDVKESVVQLLVRF
FKEVASKDVSGFHCIYETLSDSERKVLSEALL"
gene 48613..49365
/gene="DOC1"
/locus_tag="YGL240W"
/gene_synonym="APC10"
/db_xref="GeneID:852611"
mRNA 48613..49365
/gene="DOC1"
/locus_tag="YGL240W"
/gene_synonym="APC10"
/product="anaphase promoting complex subunit DOC1"
/transcript_id="NM_001181106.1"
/db_xref="GI:296144819"
/db_xref="GeneID:852611"
CDS 48613..49365
/gene="DOC1"
/locus_tag="YGL240W"
/gene_synonym="APC10"
/note="Processivity factor required for the ubiquitination
activity of the anaphase promoting complex (APC), mediates
the activity of the APC by contributing to substrate
recognition; involved in cyclin proteolysis; contains a
conserved DOC1 homology domain"
/codon_start=1
/product="anaphase promoting complex subunit DOC1"
/protein_id="NP_011274.2"
/db_xref="GI:37362650"
/db_xref="SGD:S000003209"
/db_xref="GeneID:852611"
/translation="MDPIGINKVLDHLAPSELIKPVKSCHNKPSVLVLDDRIVDAATK
DLYVNGFQEEIQYQNPTPENLQHMFHQGIEILDSARMINVTHLALWKPSSFKLGNPVD
FALDDNYDTFWQSDGGQPHQLDIMFSKRMDICVMAIFFSMIADESYAPSLVKVYAGHS
PSDARFYKMLEVRNVNGWVALRFLDNREDDQLLKCQFIRLLFPVNHENGKDTHLRGIR
LYVPSNEPHQDTHEWAQTLPETNNVFQDAILR"
gene 49552..52434
/gene="CSE1"
/locus_tag="YGL238W"
/gene_synonym="KAP109"
/db_xref="GeneID:852612"
mRNA 49552..52434
/gene="CSE1"
/locus_tag="YGL238W"
/gene_synonym="KAP109"
/product="Cse1p"
/transcript_id="NM_001181104.1"
/db_xref="GI:296144820"
/db_xref="GeneID:852612"
CDS 49552..52434
/gene="CSE1"
/locus_tag="YGL238W"
/gene_synonym="KAP109"
/note="Nuclear envelope protein that mediates the nuclear
export of importin alpha (Srp1p), homolog of metazoan CAS
protein, required for accurate chromosome segregation"
/codon_start=1
/product="Cse1p"
/protein_id="NP_011276.1"
/db_xref="GI:6321198"
/db_xref="SGD:S000003207"
/db_xref="GeneID:852612"
/translation="MSDLETVAKFLAESVIASTAKTSERNLRQLETQDGFGLTLLHVI
ASTNLPLSTRLAGALFFKNFIKRKWVDENGNHLLPANNVELIKKEIVPLMISLPNNLQ
VQIGEAISSIADSDFPDRWPTLLSDLASRLSNDDMVTNKGVLTVAHSIFKRWRPLFRS
DELFLEIKLVLDVFTAPFLNLLKTVDEQITANENNKASLNILFDVLLVLIKLYYDFNC
QDIPEFFEDNIQVGMGIFHKYLSYSNPLLEDPDETEHASVLIKVKSSIQELVQLYTTR
YEDVFGPMINEFIQITWNLLTSISNQPKYDILVSKSLSFLTAVTRIPKYFEIFNNESA
MNNITEQIILPNVTLREEDVELFEDDPIEYIRRDLEGSDTDTRRRACTDFLKELKEKN
EVLVTNIFLAHMKGFVDQYMSDPSKNWKFKDLYIYLFTALAINGNITNAGVSSTNNLL
NVVDFFTKEIAPDLTSNNIPHIILRVDAIKYIYTFRNQLTKAQLIELMPILATFLQTD
EYVVYTYAAITIEKILTIRESNTSPAFIFHKEDISNSTEILLKNLIALILKHGSSPEK
LAENEFLMRSIFRVLQTSEDSIQPLFPQLLAQFIEIVTIMAKNPSNPRFTHYTFESIG
AILNYTQRQNLPLLVDSMMPTFLTVFSEDIQEFIPYVFQIIAFVVEQSATIPESIKPL
AQPLLAPNVWELKGNIPAVTRLLKSFIKTDSSIFPDLVPVLGIFQRLIASKAYEVHGF
DLLEHIMLLIDMNRLRPYIKQIAVLLLQRLQNSKTERYVKKLTVFFGLISNKLGSDFL
IHFIDEVQDGLFQQIWGNFIITTLPTIGNLLDRKIALIGVLNMVINGQFFQSKYPTLI
SSTMNSIIETASSQSIANLKNDYVDLDNLEEISTFGSHFSKLVSISEKPFDPLPEIDV
NNGVRLYVAEALNKYNAISGNTFLNTILPQLTQENQVKLNQLLVGN"
gene complement(52731..53528)
/gene="HAP2"
/locus_tag="YGL237C"
/db_xref="GeneID:852614"
mRNA complement(52731..53528)
/gene="HAP2"
/locus_tag="YGL237C"
/product="Hap2p"
/transcript_id="NM_001181103.1"
/db_xref="GI:296144821"
/db_xref="GeneID:852614"
CDS complement(52731..53528)
/gene="HAP2"
/locus_tag="YGL237C"
/note="Subunit of the heme-activated, glucose-repressed
Hap2p/3p/4p/5p CCAAT-binding complex, a transcriptional
activator and global regulator of respiratory gene
expression; contains sequences sufficient for both complex
assembly and DNA binding"
/codon_start=1
/product="Hap2p"
/protein_id="NP_011277.1"
/db_xref="GI:6321200"
/db_xref="SGD:S000003206"
/db_xref="GeneID:852614"
/translation="MSADETDAKFHPLETDLQSDTAAATSTAAASRSPSLQEKPIEMP
LDMGKAPSPRGEDQRVTNEEDLFLFNRLRASQNRVMDSLEPQQQSQYTSSSVSTMEPS
ADFTSFSAVTTLPPPPHQQQQQQQQQQQQQQLVVQAQYTQNQPNLQSDVLGTAIAEQP
FYVNAKQYYRILKRRYARAKLEEKLRISRERKPYLHESRHKHAMRRPRGEGGRFLTAA
EIKAMKSKKSGASDDPDDSHEDKKITTKIIQEQPHATSTAAAADKKT"
gene complement(53787..55796)
/gene="MTO1"
/locus_tag="YGL236C"
/gene_synonym="IPS1"
/db_xref="GeneID:852616"
mRNA complement(53787..55796)
/gene="MTO1"
/locus_tag="YGL236C"
/gene_synonym="IPS1"
/product="Mto1p"
/transcript_id="NM_001181102.1"
/db_xref="GI:296144822"
/db_xref="GeneID:852616"
CDS complement(53787..55796)
/gene="MTO1"
/locus_tag="YGL236C"
/gene_synonym="IPS1"
/note="Mitochondrial protein, forms a heterodimer complex
with Mss1p that performs the 5-carboxymethylaminomethyl
modification of the wobble uridine base in mitochondrial
tRNAs; required for respiration in paromomycin-resistant
15S rRNA mutants"
/codon_start=1
/product="Mto1p"
/protein_id="NP_011278.2"
/db_xref="GI:50593214"
/db_xref="SGD:S000003205"
/db_xref="GeneID:852616"
/translation="MLRVTTLASSCTSFPLQVLRRRLTISSLTSFQPTTKTQVVVIGA
GHAGCEAAAASSRTGAHTTLITPSLTDIGKCSCNPSIGGVGKGILVKEIDALDGLMGK
VTDLAGVQFKMLNRSKGPAVWGPRAQIDRELYKKYMQRELSDKKAHPNLSLLQNKVAD
LILYDPGCGHKVIKGVVLDDGTQVGADQVIITTGTFLSAEIHIGDKRIAAGRIGEQPT
YGISNTLQNEVGFQLGRLKTGTPARLAKESIDFSALEVQKGDALPVPMSFLNETVSVE
PTKQLDCFGTHTTPQMHDFLRNNLHQSIHIQDTTIKGPRYCPSIEAKILRFPDRSSHK
IWLEPEGFNSDVIYPNGISNSMPEDVQLQMMRLIPGMANVEILQPAYGVEYDYVDPRQ
LKPSLETKLVDGLFLAGQINGTTGYEEAAAQGIIAGINAGLLSRQEREQLVLKRSEAY
IGVLIDDLINNGVIEPYRMFTSRSEFRISVRADNADFRLTPIGAQLGIISPVRLSQYS
RDKHLYDETIRALQNFKLSSQKWSSLLQANIAPQAENRSAWEIFRFKDMDLHKLYECI
PDLPINLLDIPMHVVTKINIQGKYEPYIVKQNQFVKAFQADENMLLPQDYDYRQLPTL
STECKLLLNRVQPLTIGQARRIQGITAAALFELYRVARKPSQPVM"
gene 55279..55815
/locus_tag="YGL235W"
/db_xref="GeneID:852615"
mRNA 55279..55815
/locus_tag="YGL235W"
/product="hypothetical protein"
/transcript_id="NM_001181101.1"
/db_xref="GI:296144823"
/db_xref="GeneID:852615"
CDS 55279..55815
/locus_tag="YGL235W"
/note="hypothetical protein; potential Cdc28p substrate;
null mutant displays increased resistance to antifungal
agents gliotoxin, cycloheximide and H2O2"
/codon_start=1
/product="hypothetical protein"
/protein_id="NP_011279.1"
/db_xref="GI:6321201"
/db_xref="SGD:S000003204"
/db_xref="GeneID:852615"
/translation="MTLWPHPGSYKIKSATLFCSRDKLGCAFLSESSLCMYFLYNSLS
IWALGPHTAGPLLLFSILNCTPARSVTLPISPSRASISFTRMPLPTPPIEGLHEHLPI
SVNDGVMRVVCAPVLDDAAAASQPACPAPMTTTCVLVVGWKLVKEDMVNRLLRTCKGN
EVHEDAKVVTRSIVLWGV"
gene 56482..58890
/gene="ADE5,7"
/locus_tag="YGL234W"
/db_xref="GeneID:852617"
mRNA 56482..58890
/gene="ADE5,7"
/locus_tag="YGL234W"
/product="bifunctional aminoimidazole ribotide
synthase/glycinamide ribotide synthase"
/transcript_id="NM_001181100.1"
/db_xref="GI:296144824"
/db_xref="GeneID:852617"
CDS 56482..58890
/gene="ADE5,7"
/locus_tag="YGL234W"
/EC_number="6.3.4.13"
/EC_number="6.3.3.1"
/note="Bifunctional enzyme of the 'de novo' purine
nucleotide biosynthetic pathway, contains aminoimidazole
ribotide synthetase and glycinamide ribotide synthetase
activities"
/codon_start=1
/product="bifunctional aminoimidazole ribotide
synthase/glycinamide ribotide synthase"
/protein_id="NP_011280.1"
/db_xref="GI:6321203"
/db_xref="SGD:S000003203"
/db_xref="GeneID:852617"
/translation="MLNILVLGNGAREHVLVTKLAQSPTVGKIYVAPGNGGTATMDPS
RVINWDITPDVANFARLQSMAVEHKINLVVPGPELPLVNGITSVFHSVGIPVFGPSVK
AAQLEASKAFSKRFMSKHNIPTASYDVFTNPEEAISFLQAHTDKAFVIKADGIAAGKG
VIIPSSIDESVQAIKDIMVTKQFGEEAGKQVVIEQFLEGDEISLLTIVDGYSHFNLPV
AQDHKRIFDGDKGLNTGGMGAYAPAPVATPSLLKTIDSQIVKPTIDGMRRDGMPFVGV
LFTGMILVKDSKTNQLVPEVLEYNVRFGDPETQAVLSLLDDQTDLAQVFLAAAEHRLD
SVNIGIDDTRSAVTVVVAAGGYPESYAKGDKITLDTDKLPPHTQIFQAGTKYDSATDS
LLTNGGRVLSVTSTAQDLRTAVDTVYEAVKCVHFQNSYYRKDIAYRAFQNSESSKVAI
TYADSGVSVDNGNNLVQTIKEMVRSTRRPGADSDIGGFGGLFDLAQAGFRQNEDTLLV
GATDGVGTKLIIAQETGIHNTVGIDLVAMNVNDLVVQGAEPLFFLDYFATGALDIQVA
SDFVSGVANGCIQSGCALVGGETSEMPGMYPPGHYDTNGTAVGAVLRQDILPKINEMA
AGDVLLGLASSGVHSNGFSLVRKIIQHVALPWDAPCPWDESKTLGEGILEPTKIYVKQ
LLPSIRQRLLLGLAHITGGGLVENIPRAIPDHLQARVDMSTWEVPRVFKWFGQAGNVP
HDDILRTFNMGVGMVLIVKRENVKAVCDSLTEEGEIIWELGSLQERPKDAPGCVIENG
TKLY"
gene 59122..61854
/gene="SEC15"
/locus_tag="YGL233W"
/db_xref="GeneID:852618"
mRNA 59122..61854
/gene="SEC15"
/locus_tag="YGL233W"
/product="Sec15p"
/transcript_id="NM_001181099.1"
/db_xref="GI:296144825"
/db_xref="GeneID:852618"
CDS 59122..61854
/gene="SEC15"
/locus_tag="YGL233W"
/note="Essential 113kDa subunit of the exocyst complex
(Sec3p, Sec5p, Sec6p, Sec8p, Sec10p, Sec15p, Exo70p, and
Exo84p), which mediates polarized targeting of vesicles to
active sites of exocytosis; Sec15p associates with Sec4p
and vesicles"
/codon_start=1
/product="Sec15p"
/protein_id="NP_011281.1"
/db_xref="GI:6321204"
/db_xref="SGD:S000003202"
/db_xref="GeneID:852618"
/translation="MDQEGQPLLSKDFQQVLLATASGNNSSWTERAVLNNESTDAVKH
EPALGQNDVFDLDPLSFDKWVPFLRRALDKNQLDPVIDELENSIEDNFQGLELQLLQD
SQMNDKLETSIDEIANIQGMVQDTLSSEISKFQIRLSESANELIVKKQMYVNNKKISL
KISEATILITKVVRILELSSKCQELITERKFFKVLQNLDSLEKLYLQEFKNYNFQFLI
EIYNSIPFLQKVTKDECINLIRNSLNLNLGKNLIKVGQEFVAIYENELLPQWLETRSK
MKLTNFKFNSPIEISMRDESFLAKLNLGEFFQLDDFHDSIMIFQNLNELSVLSGEFNK
EYELRKTKLMYPLIWKKNKTAAYQMDSLLRGTGTTPGSTAHDVSTDDPFTQSLSLHFL
QDYFLKILGFLLYDINLNKATEFILVDNNYNSTNEFWDGLMDRLSPYLSYFIDEKLKT
EEDMIKLKDFLCIYVAILENFKLNIEPLYKILVSIFEKFCSVSLRAFDDEFQILLNDD
DFMPLSINDKTLYEKVLKICWMKEGEHLSLPDPTNGEPFAVTLPFSPLYPMTCTLAKK
TYSKITAFLSIFYRHELHTLNNILVKTMDDIFNDIVNKKIRSKLESTSREEIAQILVN
LDYFIIAAKEFSNFMTRENILQNPDMEIRLSSIKYLAESRKLAETKLIELIDSKISDI
LETIEIDWQITEVRQDPDISIIDLAQFLEMMFASTLQNLPYSVQTLLIFREFDSLTRQ
FMGLLLHDTPSTITHESIMNFEVDVNYLESIIPRIFPSTPGTIDSNGYQSPMTPSTPT
FPNANGVDAPTLFENNIKSLEATFMELKQCIELLKTQGKDYNEPEIRLRKYSRIRQED
AALLLSKIQHFVSSVEGANGDDTSVMDSSSIFNSESASVIDSNTSRIAKFFNRR"
gene 62075..63002
/gene="TAN1"
/locus_tag="YGL232W"
/db_xref="GeneID:852619"
mRNA join(62075..62131,62190..63002)
/gene="TAN1"
/locus_tag="YGL232W"
/product="Tan1p"
/transcript_id="NM_001181098.1"
/db_xref="GI:296144826"
/db_xref="GeneID:852619"
CDS join(62075..62131,62190..63002)
/gene="TAN1"
/locus_tag="YGL232W"
/EC_number="2.3.-.-"
/note="Putative tRNA acetyltransferase; RNA-binding
protein required for the formation of the modified
nucleoside N(4)-acetylcytidine in serine and leucine tRNAs
but not required for the same modification in 18S rRNA;
protein abundance increases in response to DNA replication
stress"
/codon_start=1
/product="Tan1p"
/protein_id="NP_011282.1"
/db_xref="GI:6321205"
/db_xref="SGD:S000003201"
/db_xref="GeneID:852619"
/translation="MGEKRNRNGKDANSQNRKKFKVSSGFLDPGTSGIYATCSRRHER
QAAQELQLLFEEKFQELYGDIKEGEDESENDEKKDLSIEDQIKKELQELKGEETGKDL
SSGETKKKDPLAFIDLNCECVTFCKTRKPIVPEEFVLSIMKDLADPKNMVKRTRYVQK
LTPITYSCNAKMEQLIKLANLVIGPHFHDPSNVKKNYKFAVEVTRRNFNTIERMDIIN
QVVKLVNKEGSEFNHTVDLKNYDKLILVECFKSNIGMCVVDGDYKTKYRKYNVQQLYE
SKFRKDEDKSVKQ"
gene complement(63048..63620)
/gene="EMC4"
/locus_tag="YGL231C"
/db_xref="GeneID:852620"
mRNA complement(63048..63620)
/gene="EMC4"
/locus_tag="YGL231C"
/product="Emc4p"
/transcript_id="NM_001181097.1"
/db_xref="GI:296144827"
/db_xref="GeneID:852620"
CDS complement(63048..63620)
/gene="EMC4"
/locus_tag="YGL231C"
/note="Member of a transmembrane complex required for
efficient folding of proteins in the ER; null mutant
displays induction of the unfolded protein response; human
ortholog TMEM85 may function in apoptosis"
/codon_start=1
/product="Emc4p"
/protein_id="NP_011283.1"
/db_xref="GI:6321206"
/db_xref="SGD:S000003200"
/db_xref="GeneID:852620"
/translation="MSEQEPYEWAKHLLDTKYIEKYNIQNSNTLPSPPGFEGNSSKGN
VTRKQQDATSQTTSLAQKNQITVLQVQKAWQIALQPAKSIPMNIFMSYMSGTSLQIIP
IMTALMLLSGPIKAIFSTRSAFKPVLGNKATQSQVQTAMFMYIVFQGVLMYIGYRKLN
SMGLIPNAKGDWLPWERIAHYNNGLQWFSD"
gene complement(63772..64215)
/locus_tag="YGL230C"
/db_xref="GeneID:852621"
mRNA complement(63772..64215)
/locus_tag="YGL230C"
/product="hypothetical protein"
/transcript_id="NM_001181096.1"
/db_xref="GI:296144828"
/db_xref="GeneID:852621"
CDS complement(63772..64215)
/locus_tag="YGL230C"
/note="hypothetical protein; non-essential gene"
/codon_start=1
/product="hypothetical protein"
/protein_id="NP_011284.1"
/db_xref="GI:6321207"
/db_xref="SGD:S000003199"
/db_xref="GeneID:852621"
/translation="MGIITLSGNVLHLLKAYPKKGLEEVSQPEPNTANDSSTEYKGKS
KDDFQMVEKSNTDERYNFTRTKKWFLLMTSEYYKLMENRLLMFCIIACSFICAIQFLF
FIIYWTNIVPRKTQRAITNLNYDYLTAHLKEQCVPYAKILDQCIL"
rep_origin 64281..64529
/note="ARS702;
Autonomously Replicating Sequence"
/db_xref="SGD:S000118451"
gene complement(64503..66959)
/gene="SAP4"
/locus_tag="YGL229C"
/db_xref="GeneID:852622"
mRNA complement(64503..66959)
/gene="SAP4"
/locus_tag="YGL229C"
/product="Sap4p"
/transcript_id="NM_001181095.1"
/db_xref="GI:296144829"
/db_xref="GeneID:852622"
CDS complement(64503..66959)
/gene="SAP4"
/locus_tag="YGL229C"
/note="Protein required for function of the Sit4p protein
phosphatase, member of a family of similar proteins that
form complexes with Sit4p, including Sap155p, Sap185p, and
Sap190p"
/codon_start=1
/product="Sap4p"
/protein_id="NP_011285.1"
/db_xref="GI:6321208"
/db_xref="SGD:S000003198"
/db_xref="GeneID:852622"
/translation="MSLWPFGETLSHSGIDSILEEYYLIFRSLEGNETSSTDDKKNEP
SMESESEFGTESRDRSDLNQSFIDRILLETALLDELNGAANDRLVDFICLGYFYDDRS
QQVRHMDYLVDMLMAYLKDIDRTGYRTPFLLENSFHQTGEYEDQDDEDPMLYVNIISS
IFCSKSAPIVEALVQNTPFLSSLFEVFQFENIEAENCPILAVFLKINETLLFEQTSSY
LEFFKSQPNIVDKFLYHIEVSPLVEFLIKIMLTDQVESPTNIIDFLYHQDLIPKCLNL
LENSKYSPGIQNSSGELLKALISISTNFKLDTLWIGPNRLTRQLASPQYVDQLINIIL
FQRGHAMGVAVSIIIELIRKNNSDYDEVDLLSTTIVDNPPSQRDPVYLGHLLYELTMH
MEDFYALLIKLENDDDDDHDTASKALPSVKHHLLENQLHESFRPLGFERVKITELISE
MLHCSNMGLMNSKRGEKIARTRDKCRDTLDQNSLEKAMKNLNINDNTITSNTLEDKCN
NNDSNDSNDNQKQKKNIKKKFHDNELYSTFDTSDDNIDDDDDMSFEIPYVSETQNLKI
RKNPTIGDLFKIKLHDLGFFPKFLQLFLRYPWNNFWHNIVFDIIQQIFNGRMDFSYNS
FLVYSLFDFKKSTRFIPKPLYGSNQKLPVKDFHIISDFILQGHKDSFEFYEKEKTNLG
YMGQLVLIAEEIAKYSKIYKTDLIAPDIYAFLQDEVWMSYSSDILNETRTMCSIILGG
GQFCAESDENTNQDFLEKADMSKPAHPSTMDENEIVHEEDVKLHDKVAELIDELGQLT
ELDIHDKIKDVIVDHHSDLN"
gene 67598..69331
/gene="SHE10"
/locus_tag="YGL228W"
/db_xref="GeneID:852623"
mRNA 67598..69331
/gene="SHE10"
/locus_tag="YGL228W"
/product="She10p"
/transcript_id="NM_001181094.1"
/db_xref="GI:296144830"
/db_xref="GeneID:852623"
CDS 67598..69331
/gene="SHE10"
/locus_tag="YGL228W"
/note="Putative glycosylphosphatidylinositol
(GPI)-anchored hypothetical protein; overexpression causes
growth arrest"
/codon_start=1
/product="She10p"
/protein_id="NP_011286.1"
/db_xref="GI:6321209"
/db_xref="SGD:S000003197"
/db_xref="GeneID:852623"
/translation="MGKLIKLITTLTVLVSLLQYCCEFNSGSISCERTQTLCHYTNPR
VWNTYFSRNCELYKNKVSPGFDIVARKYDTAVKPVIDDATVKVNKVAIQPAFKVIHSQ
CKKWNCGKYYQLVRSPMVKTRRFFFAKYNAFVKPNLDKFFTAEFRSHLKERILKYKNI
GHYYFTITSRCIKSKYDFIVGNTEEKLMGKFKNKDTHGIHGSVTREPSSEDMVLTVST
MESDEEELTTTSTQTVVETITLDQEEASAVANHAHDDEASTDVEGSTDVNVNEQALLQ
EDFDMWSETILQKTQDVIQLFEKDVSKYINGKLVEEANHFKAKFQSLDDKSKKFFSKI
SLAINDIECVEGIDSETGKKIFFDKSGSTEISQYITRELVREYFNETRSTLDELTNAM
EKDLSEITDEIEKKVNAIREENVEVFEEWGDIIVNEWSKRMAYVDVINAHMGADDDTT
LDEEKAKSSVNWKKFLKGKKQIIESRDKLAHHSADLSRVNAFRQKVQKKILSFTQESG
EFLYILRSKANLQFQERERKERERKEREKAAAEEFQRQQELLRQQEEEDEEDVSYTST
STITTTITMTL"
gene 69671..72547
/gene="VID30"
/locus_tag="YGL227W"
/gene_synonym="GID1"
/db_xref="GeneID:852624"
mRNA 69671..72547
/gene="VID30"
/locus_tag="YGL227W"
/gene_synonym="GID1"
/product="glucose-induced degradation complex subunit
VID30"
/transcript_id="NM_001181093.1"
/db_xref="GI:296144831"
/db_xref="GeneID:852624"
CDS 69671..72547
/gene="VID30"
/locus_tag="YGL227W"
/gene_synonym="GID1"
/note="Central component of GID Complex, involved in
FBPase degradation; interacts strongly with Gid8p to serve
as a scaffold for other GID Complex subunits; contains
SPRY domain and 3 domains that are also found in Gid8p -
LisH, CTLH, and CRA; required for association of Vid
vesicles and actin patches in vacuole import and
degradation pathway; shifts the balance of nitrogen
metabolism toward glutamate production; localizes to the
nucleus and the cytoplasm"
/codon_start=1
/product="glucose-induced degradation complex subunit
VID30"
/protein_id="NP_011287.1"
/db_xref="GI:6321210"
/db_xref="SGD:S000003196"
/db_xref="GeneID:852624"
/translation="MSEYMDDVDREFINCLFPSYLLQQPVAYDLWILYLQHRKLFHKL
KNTNLINADENPTGVGMGRTKLTALTRKEIWSKLMNLGVLGTISFEAVNDDYLIQVYK
YFYPDVNDFTLRFGVKDSNKNSVRVMKASSDMRKNAQELLEPVLSEREMALNSNTSLE
NDRNDDDDDDDDDDDDDDDDDDDDDESDLESLEGEVDTDTDDNNEGDGSDNHEEGGEE
GSRGADADVSSAQQRAERVADPWIYQRSRSAINIETESRNLWDTSDKNSGLQYYPPDQ
SPSSSFSSPRVSSGNDKNDNEATNVLSNSGSKKKNSMIPDIYKILGYFLPSRWQAQPN
NSLQLSQDGITHLQPNPDYHSYMTYERSSASSASTRNRLRTSFENSGKVDFAVTWANK
SLPDNKLTIFYYEIKVLSVTSTESAENSNIVIGYKLVENELMEATTKKSVSRSSVAGS
SSSLGGSNNMSSNRVPSTSFTMEGTQRRDYIYEGGVSAMSLNVDGSINKCQKYGFDLN
VFGYCGFDGLITNSTEQSKEYAKPFGRDDVIGCGINFIDGSIFFTKNGIHLGNAFTDL
NDLEFVPYVALRPGNSIKTNFGLNEDFVFDIIGYQDKWKSLAYEHICRGRQMDVSIEE
FDSDESEEDETENGPEENKSTNVNEDLMDIDQEDGAAGNKDTKKLNDEKDNNLKFLLG
EDNRFIDGKLVRPDVNNINNLSVDDGSLPNTLNVMINDYLIHEGLVDVAKGFLKDLQK
DAVNVNGQHSESKDVIRHNERQIMKEERMVKIRQELRYLINKGQISKCINYIDNEIPD
LLKNNLELVFELKLANYLVMIKKSSSKDDDEIENLILKGQELSNEFIYDTKIPQSLRD
RFSGQLSNVSALLAYSNPLVEAPKEISGYLSDEYLQERLFQVSNNTILTFLHKDSECA
LENVISNTRAMLSTLLEYNAFGSTNSSDPRYYKAINFDEDVLNL"
gene complement(72749..73158)
/gene="OST5"
/locus_tag="YGL226C-A"
/db_xref="GeneID:852625"
mRNA complement(join(72749..72988,73138..73158))
/gene="OST5"
/locus_tag="YGL226C-A"
/product="Ost5p"
/transcript_id="NM_001181091.1"
/db_xref="GI:296144832"
/db_xref="GeneID:852625"
CDS complement(join(72749..72988,73138..73158))
/gene="OST5"
/locus_tag="YGL226C-A"
/EC_number="2.4.99.18"
/note="Zeta subunit of the oligosaccharyltransferase
complex of the ER lumen, which catalyzes asparagine-linked
glycosylation of newly synthesized proteins"
/codon_start=1
/product="Ost5p"
/protein_id="NP_011288.1"
/db_xref="GI:6321211"
/db_xref="SGD:S000003194"
/db_xref="GeneID:852625"
/translation="MTYEQLYKEFHSSKSFQPFIHLDTQPKFAICGLIVTLAVLSSAL
FAVGSKSSYIKKLFFYTILSVIGSLFAGLTTVFASNSFGVYV"
gene 73340..73711
/gene="MTC3"
/locus_tag="YGL226W"
/db_xref="GeneID:852626"
mRNA 73340..73711
/gene="MTC3"
/locus_tag="YGL226W"
/product="Mtc3p"
/transcript_id="NM_001181092.1"
/db_xref="GI:296144833"
/db_xref="GeneID:852626"
CDS 73340..73711
/gene="MTC3"
/locus_tag="YGL226W"
/note="hypothetical protein; green fluorescent protein
(GFP)-fusion protein localizes to the mitochondrion; mtc3
is synthetically sick with cdc13-1"
/codon_start=1
/product="Mtc3p"
/protein_id="NP_011289.1"
/db_xref="GI:6321212"
/db_xref="SGD:S000003195"
/db_xref="GeneID:852626"
/translation="MMGRNGIRLALKRSFSTYQPPVVEITNITKLWPTLRPEVRDEIK
EYLRWRMQEDWRHIPLEETKAAYFLSYGPCGGRSKGNEWNVGYTGMRIVFNLVLFGGA
ATAFYNWKQDKKLEEQLRDLV"
gene complement(73829..73902)
/locus_tag="tV(AAC)G3"
/db_xref="GeneID:852627"
tRNA complement(73829..73902)
/locus_tag="tV(AAC)G3"
/product="tRNA-Val"
/note="Valine tRNA (tRNA-Val), predicted by tRNAscan-SE
analysis"
/db_xref="SGD:S000006757"
/db_xref="GeneID:852627"
gene 76894..77907
/gene="VRG4"
/locus_tag="YGL225W"
/gene_synonym="GOG5; LDB3; VAN2; VIG4"
/db_xref="GeneID:852647"
mRNA 76894..77907
/gene="VRG4"
/locus_tag="YGL225W"
/gene_synonym="GOG5; LDB3; VAN2; VIG4"
/product="Vrg4p"
/transcript_id="NM_001181090.1"
/db_xref="GI:296144834"
/db_xref="GeneID:852647"
CDS 76894..77907
/gene="VRG4"
/locus_tag="YGL225W"
/gene_synonym="GOG5; LDB3; VAN2; VIG4"
/note="Golgi GDP-mannose transporter; regulates Golgi
function and glycosylation in Golgi"
/codon_start=1
/product="Vrg4p"
/protein_id="NP_011290.1"
/db_xref="GI:6321213"
/db_xref="SGD:S000003193"
/db_xref="GeneID:852647"
/translation="MSELKTGHAGHNPWASVANSGPISILSYCGSSILMTVTNKFVVN
LKDFNMNFVMLFVQSLVCTITLIILRILGYAKFRSLNKTDAKNWFPISFLLVLMIYTS
SKALQYLAVPIYTIFKNLTIILIAYGEVLFFGGSVTSMELSSFLLMVLSSVVATWGDQ
QAVAAKAASLAEGAAGAVASFNPGYFWMFTNCITSALFVLIMRKRIKLTNFKDFDTMF
YNNVLALPILLLFSFCVEDWSSVNLTNNFSNDSLTAMIISGVASVGISYCSGWCVRVT
SSTTYSMVGALNKLPIALSGLIFFDAPRNFLSILSIFIGFLSGIIYAVAKQKKQQAQP
LRK"
gene complement(78015..78857)
/gene="SDT1"
/locus_tag="YGL224C"
/gene_synonym="SSM1"
/db_xref="GeneID:852648"
mRNA complement(78015..78857)
/gene="SDT1"
/locus_tag="YGL224C"
/gene_synonym="SSM1"
/product="Sdt1p"
/transcript_id="NM_001181089.1"
/db_xref="GI:296144835"
/db_xref="GeneID:852648"
CDS complement(78015..78857)
/gene="SDT1"
/locus_tag="YGL224C"
/gene_synonym="SSM1"
/note="Pyrimidine nucleotidase; overexpression suppresses
the 6-AU sensitivity of transcription elongation factor
S-II, as well as resistance to other pyrimidine
derivatives"
/codon_start=1
/product="Sdt1p"
/protein_id="NP_011291.1"
/db_xref="GI:6321214"
/db_xref="SGD:S000003192"
/db_xref="GeneID:852648"
/translation="MTVEYTASDLATYQNEVNEQIAKNKAHLESLTHPGSKVTFPIDQ
DISATPQNPNLKVFFFDIDNCLYKSSTRIHDLMQQSILRFFQTHLKLSPEDAHVLNNS
YYKEYGLAIRGLVMFHKVNALEYNRLVDDSLPLQDILKPDIPLRNMLLRLRQSGKIDK
LWLFTNAYKNHAIRCLRLLGIADLFDGLTYCDYSRTDTLVCKPHVKAFEKAMKESGLA
RYENAYFIDDSGKNIETGIKLGMKTCIHLVENEVNEILGQTPEGAIVISDILELPHVV
SDLF"
gene complement(79112..80365)
/gene="COG1"
/locus_tag="YGL223C"
/gene_synonym="COD3; LDB11; SEC36"
/db_xref="GeneID:852649"
mRNA complement(79112..80365)
/gene="COG1"
/locus_tag="YGL223C"
/gene_synonym="COD3; LDB11; SEC36"
/product="Cog1p"
/transcript_id="NM_001181088.1"
/db_xref="GI:296144836"
/db_xref="GeneID:852649"
CDS complement(79112..80365)
/gene="COG1"
/locus_tag="YGL223C"
/gene_synonym="COD3; LDB11; SEC36"
/note="Essential component of the conserved oligomeric
Golgi complex (Cog1p through Cog8p), a cytosolic tethering
complex that functions in protein trafficking to mediate
fusion of transport vesicles to Golgi compartments"
/codon_start=1
/product="Cog1p"
/protein_id="NP_011292.1"
/db_xref="GI:6321215"
/db_xref="SGD:S000003191"
/db_xref="GeneID:852649"
/translation="MDEVLPLFRDSHIPQIKDYQLELQNDLTKTNEAFQKNLLKNYNK
ILSLTDSVNDLSLNLKNVDQDFKSLCFNDEKFQLNKLTPLPYQTTTHISPPRDEEKVS
IPSQNILVISNWTISINNFCNRIVTSTTPSRIFDELLLNFHELSLIPVPSKFEALVKD
KCCRLQKFLVDSMKTLNLTLLQWVKLYNLLNTEFSSKWDDDLLSIFNESLFETLFNDN
VQALLISSANSKDHQYHSNQQYKDAIVVDFVNSSTFRDHLIRRTVKEINTHLDTLSTL
RAKLKEPETLHKLDIFHDNDTNLNDGTVSPLDDDALKQYIDTAVFYSKGLTNDTTLQI
YQTVQPTIEILQNLELYKCPQETLTDLRNKLITQLQEFKTQISSRLPSPLENSTSVVD
DFITSYNNHNLLQLVIDQITQLRQQ"
gene complement(80659..81186)
/gene="EDC1"
/locus_tag="YGL222C"
/db_xref="GeneID:852650"
mRNA complement(80659..81186)
/gene="EDC1"
/locus_tag="YGL222C"
/product="Edc1p"
/transcript_id="NM_001181087.1"
/db_xref="GI:296144837"
/db_xref="GeneID:852650"
CDS complement(80659..81186)
/gene="EDC1"
/locus_tag="YGL222C"
/note="RNA-binding protein that activates mRNA decapping
directly; binds to the mRNA substrate and enhances the
activity of the decapping proteins Dcp1p and Dcp2p; has a
role in translation during heat stress; protein becomes
more abundant and forms cytoplasmic foci in response to
DNA replication stress"
/codon_start=1
/product="Edc1p"
/protein_id="NP_011293.1"
/db_xref="GI:6321216"
/db_xref="SGD:S000003190"
/db_xref="GeneID:852650"
/translation="MSTDTMYFNSSRLLPSAGRNKTNNLIKQKTRNNRARGNAAKNAN
NNNYITDIPPPQTLPNGQKPNFGHSSNKKPSFNQKKHSPPSSPSSTTTLGKKNRQNNK
ETPRQNNKDDTRLLSQNLKNLLLNQKQSPHGSQGIIPMGCNGSAKKLSHSYAGSTFAT
NGPREAKNLPKPSFL"
gene complement(81426..82292)
/gene="NIF3"
/locus_tag="YGL221C"
/db_xref="GeneID:852651"
mRNA complement(81426..82292)
/gene="NIF3"
/locus_tag="YGL221C"
/product="Nif3p"
/transcript_id="NM_001181086.1"
/db_xref="GI:296144838"
/db_xref="GeneID:852651"
CDS complement(81426..82292)
/gene="NIF3"
/locus_tag="YGL221C"
/note="hypothetical protein, similar to Listeria
monocytogenes major sigma factor (rpoD gene product); the
authentic, non-tagged protein is detected in highly
purified mitochondria in high-throughput studies"
/codon_start=1
/product="Nif3p"
/protein_id="NP_011294.1"
/db_xref="GI:6321217"
/db_xref="SGD:S000003189"
/db_xref="GeneID:852651"
/translation="MSRAITRAQLDKLVRSITKFYPQKYADKSWDNTGLLIDCSTAQV
TTADANAKTKVLLTVDLTKSVAQEAVDANCNVIVAYHPFIFPSWNRLSPHTNPQHETA
IKLIQYGISVYCPHTAVDAARGGVNDWLVRGLNNGENVAKSYALETVSGETDDLIGYG
RFVEFNKDISLEQIVKNVKRVLRVPYVQVASLAAPSAWNQLKIKKVAVCAGSGSGVFK
QLKEDVDLYYTGEMSHHEVLKWKEMGKTVIVCNHSNTERGFLQDVMKGLLQDEGHEVV
VSKMDCDPLTVA"
gene 82374..82736
/gene="FRA2"
/locus_tag="YGL220W"
/gene_synonym="AIM15"
/db_xref="GeneID:852652"
mRNA 82374..82736
/gene="FRA2"
/locus_tag="YGL220W"
/gene_synonym="AIM15"
/product="Fra2p"
/transcript_id="NM_001181085.1"
/db_xref="GI:296144839"
/db_xref="GeneID:852652"
CDS 82374..82736
/gene="FRA2"
/locus_tag="YGL220W"
/gene_synonym="AIM15"
/note="Protein involved in negative regulation of
transcription of iron regulon; forms an iron independent
complex with Fra2p, Grx3p, and Grx4p; null mutant fails to
repress iron regulon and is sensitive to nickel"
/codon_start=1
/product="Fra2p"
/protein_id="NP_011295.1"
/db_xref="GI:6321218"
/db_xref="SGD:S000003188"
/db_xref="GeneID:852652"
/translation="MTGERIEKVKINDEFAKSHFLTTQWRETKRQRHYKMPVTEQGLR
ERIESAIPQVYHIIVTDLSYGCGQSFDIVVVSDFFQGKSKLMRSRAVNKAVKEELQEI
HAFSCKCYTEEEWSKIVV"
gene complement(82878..84257)
/gene="MDM34"
/locus_tag="YGL219C"
/gene_synonym="MMM2"
/db_xref="GeneID:852654"
mRNA complement(82878..84257)
/gene="MDM34"
/locus_tag="YGL219C"
/gene_synonym="MMM2"
/product="Mdm34p"
/transcript_id="NM_001181084.1"
/db_xref="GI:296144840"
/db_xref="GeneID:852654"
CDS complement(82878..84257)
/gene="MDM34"
/locus_tag="YGL219C"
/gene_synonym="MMM2"
/note="Mitochondrial component of the ERMES complex that
links the ER to mitochondria and may promote
inter-organellar calcium and phospholipid exchange as well
as coordinating mitochondrial DNA replication and growth"
/codon_start=1
/product="Mdm34p"
/protein_id="NP_011296.1"
/db_xref="GI:6321220"
/db_xref="SGD:S000003187"
/db_xref="GeneID:852654"
/translation="MSFRFNEAVFGDNSFNERIREKLSTALNSPSKKKLDILKSGIKV
QKVDFPTIPQLEILDLDIITQPKSLAKGICKISCKDAMLRIQTVIESNLLLINEQDTP
SFTMPQLINNGSFTIPITMTFSSIELEAITNIFVKNPGIGISFNDVDLDFKFDCSVKI
LQSTIERRLKESMHVVFKDVLPSLIFNTSQNWFTNRGESTSTIPGKREHHHQQTTMSR
NVILDGSDFQELSPINMLRLSSIVSSRSTLSLHSTVMNSLSAIPGCLERQNLYRFISR
MPSLNNYYSSQSFPQPKSSTVSSKQLVKPFYCSHNLLPKTVLDSSQYDLATITKIQSR
LFDRSNSNDDNAKPRRRKIKCKKTRTPSNLQSQGEQAVDDSTAIETVTSTPVQTPIPE
LEEQSPPYLKTTVSIRDKYVIPEKISLNLDSKKDTSKKKPFYFIGLNSQEPSNNWKWG
MEDSPPPYH"
gene 84885..87302
/gene="KIP3"
/locus_tag="YGL216W"
/db_xref="GeneID:852655"
mRNA 84885..87302
/gene="KIP3"
/locus_tag="YGL216W"
/product="tubulin-dependent ATPase KIP3"
/transcript_id="NM_001181081.1"
/db_xref="GI:296144841"
/db_xref="GeneID:852655"
CDS 84885..87302
/gene="KIP3"
/locus_tag="YGL216W"
/note="Kinesin-related motor protein involved in mitotic
spindle positioning"
/codon_start=1
/product="tubulin-dependent ATPase KIP3"
/protein_id="NP_011299.1"
/db_xref="GI:6321221"
/db_xref="SGD:S000003184"
/db_xref="GeneID:852655"
/translation="MNVPETRQSSIVVAIRVRPFTSMEKTRLVNEASGAEANFPGLGD
SSLILPMSNNSDSDIDIDAEEGSTRSKRNSLLRRKVIRPEGIRKIVDCVDDRMLIFDP
ADRNPLNKVSDQVLNSMRARATKATASSINNSNATNKFSSQRRRHGGEIKFVFDKLFD
ETSSQARVYKETTSPLLDSVLDGFNSTVFAYGATGCGKTYTVSGTPSQPGIIFLAMEE
LFNKITDLKDEKDFEISLSYLEIYNERIRDLLKPETPSKRLVIREDTQNHIKVANLSY
HHPNTVEDVMDLVVQGNINRTTSPTEANEVSSRSHAVLQIHIMQTNKLVDLTSQHTFA
TLSIIDLAGSERAAATRNRGIRLHEGANINRSLLALGNCINALCLNDGSRSCHIPYRD
SKLTRLLKFSLGGNCKTVMIVCISPSSSHYDETLNTLKYANRAKEIKTKIIRNQQSLS
RHVGSYLKMITEQKRQIEELREREEKMISLKLTKYKLNKEKIQLAINECVNRVQQTYA
GVETYQVAKTLKSLILCKRRFLQMVKLEVDNLILLFEREESTAAEMQPVISNCRMISG
QLYNKIHELEMKFDETDTLSSVIHQVHSIDLNKLREMEDWDETYDLVYLESCLNQISE
LQRNEILVNSSIMTEKLMSDPGLNSRFKFLSKWLMNRTPNIESIIQDLVHIDEEFESF
ARTFIANPDSNFTNTNINIINTTAADLAVPAETLQRQNFSQKKVKWTSPDLSPSPMIE
PQPELEPELHQDQDAIASEVDVSMQDTTFNEQGPSTPSAPTTAVPRRKMRSSLLTHQS
LLATARK"
gene 87981..89339
/gene="CLG1"
/locus_tag="YGL215W"
/db_xref="GeneID:852657"
mRNA 87981..89339
/gene="CLG1"
/locus_tag="YGL215W"
/product="Clg1p"
/transcript_id="NM_001181080.1"
/db_xref="GI:296144842"
/db_xref="GeneID:852657"
CDS 87981..89339
/gene="CLG1"
/locus_tag="YGL215W"
/note="Cyclin-like protein that interacts with Pho85p; has
sequence similarity to G1 cyclins PCL1 and PCL2"
/codon_start=1
/product="Clg1p"
/protein_id="NP_011300.1"
/db_xref="GI:6321223"
/db_xref="SGD:S000003183"
/db_xref="GeneID:852657"
/translation="MANTFKYYPETMGNSSGYPISLPFPKGSATSAVNVARQLPKYLG
HVPSQSVHTQLPSMASLGYFNQPSSTYYAPPAPLQQHQQPPILPPPGLMYTSNNNSNV
IPPPVQMIRDGQQQPQQSNQVNGGVSENLDYDISIMSKFIMENAFVAFNANYSTDDQT
TDLFFKGISSVLNATRLPSATIFLAIDYLFKYINKLSNGIHSIGGNSINIIYQNTMIA
FILANKFNDDKTFTNNSWSQATGILINVINDFERQWLRIFNWELYDSAFLYFEFVKNF
EIFKQNQLKPAVAVPTLLSPIVNVGDTRNVNFNLKPTSTNNLLSPVSNYETPMLMPHN
MFSSPSYQSNSRSEFSSMNGYYNYYNYNQPRLNYYQQFPNIYSSPISETQFDYDFYNF
SSQQQQQQQKQHSLLPAAPQLPPPHVHNQSYGHHLGWKSMDDTINHSRFERNYFPYSA
VY"
gene complement(90054..91247)
/gene="SKI8"
/locus_tag="YGL213C"
/gene_synonym="REC103"
/db_xref="GeneID:852659"
mRNA complement(90054..91247)
/gene="SKI8"
/locus_tag="YGL213C"
/gene_synonym="REC103"
/product="Ski8p"
/transcript_id="NM_001181078.1"
/db_xref="GI:296144843"
/db_xref="GeneID:852659"
CDS complement(90054..91247)
/gene="SKI8"
/locus_tag="YGL213C"
/gene_synonym="REC103"
/note="Ski complex component and WD-repeat protein,
mediates 3'-5' RNA degradation by the cytoplasmic exosome;
also required for meiotic double-strand break
recombination; null mutants have superkiller phenotype"
/codon_start=1
/product="Ski8p"
/protein_id="NP_011302.1"
/db_xref="GI:6321225"
/db_xref="SGD:S000003181"
/db_xref="GeneID:852659"
/translation="MSKVFIATANAGKAHDADIFSVSACNSFTVSCSGDGYLKVWDNK
LLDNENPKDKSYSHFVHKSGLHHVDVLQAIERDAFELCLVATTSFSGDLLFYRITRED
ETKKVIFEKLDLLDSDMKKHSFWALKWGASNDRLLSHRLVATDVKGTTYIWKFHPFAD
ESNSLTLNWSPTLELQGTVESPMTPSQFATSVDISERGLIATGFNNGTVQISELSTLR
PLYNFESQHSMINNSNSIRSVKFSPQGSLLAIAHDSNSFGCITLYETEFGERIGSLSV
PTHSSQASLGEFAHSSWVMSLSFNDSGETLCSAGWDGKLRFWDVKTKERITTLNMHCD
DIEIEEDILAVDEHGDSLAEPGVFDVKFLKKGWRSGMGADLNESLCCVCLDRSIRWFR
EAGGK"
gene 91432..92382
/gene="VAM7"
/locus_tag="YGL212W"
/gene_synonym="VPL24; VPS43"
/db_xref="GeneID:852660"
mRNA 91432..92382
/gene="VAM7"
/locus_tag="YGL212W"
/gene_synonym="VPL24; VPS43"
/product="Vam7p"
/transcript_id="NM_001181077.1"
/db_xref="GI:296144844"
/db_xref="GeneID:852660"
CDS 91432..92382
/gene="VAM7"
/locus_tag="YGL212W"
/gene_synonym="VPL24; VPS43"
/note="Vacuolar SNARE protein; functions with Vam3p in
vacuolar protein trafficking; has an N-terminal PX domain
(phosphoinositide-binding module) that binds PtdIns-3-P
and mediates membrane binding; SNAP-25 homolog; protein
abundance increases in response to DNA replication stress"
/codon_start=1
/product="Vam7p"
/protein_id="NP_011303.1"
/db_xref="GI:6321226"
/db_xref="SGD:S000003180"
/db_xref="GeneID:852660"
/translation="MAANSVGKMSEKLRIKVDDVKINPKYVLYGVSTPNKRLYKRYSE
FWKLKTRLERDVGSTIPYDFPEKPGVLDRRWQRRYDDPEMIDERRIGLERFLNELYND
RFDSRWRDTKIAQDFLQLSKPNVSQEKSQQHLETADEVGWDEMIRDIKLDLDKESDGT
PSVRGALRARTKLHKLRERLEQDVQKKSLPSTEVTRRAALLRSLLKECDDIGTANIAQ
DRGRLLGVATSDNSSTTEVQGRTNNDLQQGQMQMVRDQEQELVALHRIIQAQRGLALE
MNEELQTQNELLTALEDDVDNTGRRLQIANKKARHFNNSA"
gene 92512..93591
/gene="NCS6"
/locus_tag="YGL211W"
/gene_synonym="TUC1; YGL210W-A"
/db_xref="GeneID:852661"
mRNA 92512..93591
/gene="NCS6"
/locus_tag="YGL211W"
/gene_synonym="TUC1; YGL210W-A"
/product="Ncs6p"
/transcript_id="NM_001181076.1"
/db_xref="GI:296144845"
/db_xref="GeneID:852661"
CDS 92512..93591
/gene="NCS6"
/locus_tag="YGL211W"
/gene_synonym="TUC1; YGL210W-A"
/note="Protein required for thiolation of the uridine at
the wobble position of Gln, Lys, and Glu tRNAs; has a role
in urmylation and in invasive and pseudohyphal growth;
inhibits replication of Brome mosaic virus in S.
cerevisiae"
/codon_start=1
/product="Ncs6p"
/protein_id="NP_011304.2"
/db_xref="GI:50593215"
/db_xref="SGD:S000003179"
/db_xref="GeneID:852661"
/translation="MSFTAPSDPVNKPTKVKVSQLCELCHSRKALIRRPKNLSKLCKQ
CFCLVFETEIHNTIVANNLFQRGEKVAVGASGGKDSTVLAHMLKLLNDRYDYGIEIVL
LSIDEGIIGYRDDSLATVKRNQQQYGLPLEIFSFKDLYDWTMDEIVSVAGIRNSCTYC
GVFRRQSLDRGAAKLGISHVVTGHNADDMAETVLMNILRGDVARLEKSTAIITQSSGS
PIKRSKPFKYSYQKEIVLYAHYMKLDYFSTECTYAPEAFRGTAREYMKNLEAVRPSCI
IDIIQSGENLALKAKKSNAGKRVVKFVDGNRCARCGYLSSNNICKACMLLEGLEKSRA
QVAIENDTSADGAALKLRALEKLSF"
gene 93792..94460
/gene="YPT32"
/locus_tag="YGL210W"
/db_xref="GeneID:852662"
mRNA 93792..94460
/gene="YPT32"
/locus_tag="YGL210W"
/product="Ypt32p"
/transcript_id="NM_001181075.1"
/db_xref="GI:296144846"
/db_xref="GeneID:852662"
CDS 93792..94460
/gene="YPT32"
/locus_tag="YGL210W"
/note="Rab family GTPase involved in the exocytic pathway;
very similar to Ypt31p; mediates intra-Golgi traffic or
the budding of post-Golgi vesicles from the trans-Golgi;
protein abundance increases in response to DNA replication
stress"
/codon_start=1
/product="Ypt32p"
/protein_id="NP_011305.1"
/db_xref="GI:6321228"
/db_xref="SGD:S000003178"
/db_xref="GeneID:852662"
/translation="MSNEDYGYDYDYLFKIVLIGDSGVGKSNLLSRFTTDEFNIESKS
TIGVEFATRTIEVENKKIKAQIWDTAGQERYRAITSAYYRGAVGALIVYDISKSSSYE
NCNHWLTELRENADDNVAVGLIGNKSDLAHLRAVPTDEAKNFAMENQMLFTETSALNS
DNVDKAFRELIVAIFQMVSKHQVDLSGSGTNNMGSNGAPKGPTISLTPAPKEDKKKKS
SNCC"
gene 95858..97006
/gene="MIG2"
/locus_tag="YGL209W"
/gene_synonym="MLZ1"
/db_xref="GeneID:852663"
mRNA 95858..97006
/gene="MIG2"
/locus_tag="YGL209W"
/gene_synonym="MLZ1"
/product="Mig2p"
/transcript_id="NM_001181074.1"
/db_xref="GI:296144847"
/db_xref="GeneID:852663"
CDS 95858..97006
/gene="MIG2"
/locus_tag="YGL209W"
/gene_synonym="MLZ1"
/note="Zinc finger transcriptional repressor; cooperates
with Mig1p in glucose-induced repression of many genes;
under low glucose conditions Mig2p relocalizes to
mitochondrion, where it interacts with Ups1p and
antagonizes mitochondrial fission factor, Dnm1p,
indicative of a role in mitochondrial fusion or regulating
morphology; regulates filamentous growth along with Mig2p
in response to glucose depletion; MIG2 has a paralog,
MIG3, that arose from the whole genome duplication"
/codon_start=1
/product="Mig2p"
/protein_id="NP_011306.1"
/db_xref="GI:6321229"
/db_xref="SGD:S000003177"
/db_xref="GeneID:852663"
/translation="MPKKQTNFPVDNENRPFRCDTCHRGFHRLEHKKRHLRTHTGEKP
HHCAFPGCGKSFSRSDELKRHMRTHTGQSQRRLKKASVQKQEFLTVSGIPTIASGVMI
HQPIPQVLPANMAINVQAVNGGNIIHAPNAVHPMVIPIMAQPAPIHASAASFQPATSP
MPISTYTPVPSQSFTSFQSSIGSIQSNSDVSSIFSNMNVRVNTPRSVPNSPNDGYLHQ
QHIPQQYQHQTASPSVAKQQKTFAHSLASALSTLQKRTPVSAPSTTIESPSSPSDSSH
TSASSSAISLPFSNAPSQLAVAKELESVYLDSNRYTTKTRRERAKFEIPEEQEEDTNN
SSSGSNEEEHESLDHESSKSRKKLSGVKLPPVRNLLKQIDVFNGPKRV"
gene 97338..98585
/gene="SIP2"
/locus_tag="YGL208W"
/gene_synonym="SPM2"
/db_xref="GeneID:852664"
mRNA 97338..98585
/gene="SIP2"
/locus_tag="YGL208W"
/gene_synonym="SPM2"
/product="Sip2p"
/transcript_id="NM_001181073.2"
/db_xref="GI:330443544"
/db_xref="GeneID:852664"
CDS 97338..98585
/gene="SIP2"
/locus_tag="YGL208W"
/gene_synonym="SPM2"
/note="One of three beta subunits of the Snf1
serine/threonine protein kinase complex involved in the
response to glucose starvation; null mutants exhibit
accelerated aging; N-myristoylprotein localized to the
cytoplasm and the plasma membrane"
/codon_start=1
/product="Sip2p"
/protein_id="NP_011307.1"
/db_xref="GI:6321230"
/db_xref="SGD:S000003176"
/db_xref="GeneID:852664"
/translation="MGTTTSHPAQKKQTTKKCRAPIMSDVREKPSNAQGCEPQEMDAV
SKKVTELSLNKCSDSQDAGQPSREGSITKKKSTLLLRDEDEPTMPKLSVMETAVDTDS
GSSSTSDDEEGDIIAQTTEPKQDASPDDDRSGHSSPREEGQQQIRAKEASGGPSEIKS
SLMVPVEIRWQQGGSKVYVTGSFTKWRKMIGLIPDSDNNGSFHVKLRLLPGTHRFRFI
VDNELRVSDFLPTATDQMGNFVNYIEVRQPEKNPTNEKIRSKEADSMRPPTSDRSSIA
LQIGKDPDDFGDGYTRFHEDLSPRPPLEYTTDIPAVFTDPSVMERYYYTLDRQQSNTD
TSWLTPPQLPPQLENVILNKYYATQDQFNENNSGALPIPNHVVLNHLVTSSIKHNTLC
VASIVRYKQKYVTQILYTPIESS"
gene 98969..102076
/gene="SPT16"
/locus_tag="YGL207W"
/gene_synonym="CDC68; SSF1"
/db_xref="GeneID:852665"
mRNA 98969..102076
/gene="SPT16"
/locus_tag="YGL207W"
/gene_synonym="CDC68; SSF1"
/product="Spt16p"
/transcript_id="NM_001181072.1"
/db_xref="GI:296144849"
/db_xref="GeneID:852665"
CDS 98969..102076
/gene="SPT16"
/locus_tag="YGL207W"
/gene_synonym="CDC68; SSF1"
/note="Subunit of the heterodimeric FACT complex
(Spt16p-Pob3p), which associates with chromatin via
interaction with Nhp6Ap and Nhp6Bp, and reorganizes
nucleosomes to facilitate access to DNA by RNA and DNA
polymerases; some mutations cause reduced nucleosome
occupancy over highly transcribed regions of the yeast
genome"
/codon_start=1
/product="Spt16p"
/protein_id="NP_011308.1"
/db_xref="GI:6321231"
/db_xref="SGD:S000003175"
/db_xref="GeneID:852665"
/translation="MEELNIDFDVFKKRIELLYSKYNEFEGSPNSLLFVLGSSNAENP
YQKTTILHNWLLSYEFPATLIALVPGKVIIITSSAKAKHLQKAIDLFKDPESKITLEL
WQRNNKEPELNKKLFDDVIALINSAGKTVGIPEKDSYQGKFMTEWNPVWEAAVKENEF
NVIDISLGLSKVWEVKDVNEQAFLSVSSKGSDKFMDLLSNEMVRAVDEELKITNAKLS
DKIENKIDDVKFLKQLSPDLSALCPPNYKFNFDLLDWTYSPIIQSGKKFDLRVSARST
NDQLYGNGCILASCGIRYNNYCSNITRTFLIDPSEEMANNYDFLLTLQKEIVTNILKP
GRTPKEVYESVIEYIEKTKPELVPNFTKNIGSLIGLEFRDSNFILNVKNDYRKIQRGD
CFNISFGFNNLKDSQSANNYALQLADTVQIPLDETEPPRFLTNYTKAKSQISFYFNNE
EEDNNKKKSSPATKVPSKPDRNSKILRTKLRGEARGGAEDAQKEQIRKENQKKLHEKL
EKNGLLRFSAADANGPDSEPRQYFKKYESYVRDSQLPTNIRDLRIHVDWKSQTIILPI
YGRPVPFHINSYKNGSKNEEGEYTYLRLNFNSPGSSGGISKKVEELPYEESADNQFVR
SITLRSKDGDRMSETFKQIADLKKEATKREQERKALADVVQQDKLIENKTGRTKRLDQ
IFVRPNPDTKRVPSTVFIHENGIRFQSPLRTDSRIDILFSNIKNLIFQSCKGELIVVI
HIHLKNPILMGKKKIQDVQFYREASDMSVDETGGGRRGQSRFRRYGDEDELEQEQEER
RKRAALDKEFKYFADAIAEASNGLLTVENTFRDLGFQGVPNRSAVFCMPTTDCLVQLI
EPPFLVINLEEVEICILERVQFGLKNFDMVFVYKDFNKPVTHINTVPIESLDFLKQWL
TDMDIPYTVSTINLNWATIMKSLQDDPYQFFLDGGWNFLATGSDDEASDESEEEVSEY
EASEDDVSDESAFSEDEEGSEVDDDISGDESEDYTGDESEEGEDWDELEKKAARADRG
ANFRD"
gene complement(102543..107504)
/gene="CHC1"
/locus_tag="YGL206C"
/gene_synonym="SWA5"
/db_xref="GeneID:852666"
mRNA complement(102543..107504)
/gene="CHC1"
/locus_tag="YGL206C"
/gene_synonym="SWA5"
/product="Chc1p"
/transcript_id="NM_001181071.1"
/db_xref="GI:296144850"
/db_xref="GeneID:852666"
CDS complement(102543..107504)
/gene="CHC1"
/locus_tag="YGL206C"
/gene_synonym="SWA5"
/note="Clathrin heavy chain, subunit of the major coat
protein involved in intracellular protein transport and
endocytosis; two heavy chains form the clathrin triskelion
structural component; the light chain (CLC1) is thought to
regulate function"
/codon_start=1
/product="Chc1p"
/protein_id="NP_011309.1"
/db_xref="GI:6321232"
/db_xref="SGD:S000003174"
/db_xref="GeneID:852666"
/translation="MSDLPIEFTELVDLMSLGISPQFLDFRSTTFESDHFVTVRETKD
GTNSVAIVDLAKGNEVTRKNMGGDSAIMHPSQMVISVRANGTIVQIFNLETKSKLKSF
TLDEPVIFWRWLSETTLGFVTARSILTSNVFDGNVNAKPQLLTLRHANLNNTQIINFV
ANKNLDWFAVVGILQENGRIAGRIQLFSKQRNISQAIDGHVAIFTNILLEGNGSTPVQ
VFVTGNRNATTGAGELRIIEIDHDASLPSQYQKETTDIFFPPDATNDFPIAVQVSEKY
GIIYLLTKYGFIHLYELETGTNLFVNRITAESVFTAAPYNHENGIACINKKGQVLAVE
ISTSQIVPYILNKLSNVALALIVATRGGLPGADDLFQKQFESLLLQNDYQNAAKVAAS
STSLRNQNTINRLKNIQAPPGAISPILLYFSTLLDKGKLNKEETIELARPVLQQDRKQ
LFEKWLKEDKLECSEELGDIVKPFDTTLALACYLRAGAHAKVISCLAELQQFEKIIPY
CQKVGYQPNFLVLISSLIRSSPDRASEFAVSLLQNPETASQIDIEKIADLFFSQNHIQ
QGTSLLLDALKGDTPDQGHLQTRVLEVNLLHAPQVADAILGNNIFSHYDKPTIASLSE
KAGLYQRALENYTDIKDIKRCVVHTNALPIDWLVGYFGKLNVEQSLACLKALMDNNIQ
ANIQTVVQVATKFSDLIGPSTLIKLFEDYNATEGLYYYLASLVNLTEDKDVVYKYIEA
AAKMKQYREIERIVKDNNVYDPERVKNFLKDANLEDQLPLVIVCDRFDFVHEMILYLY
KSQNLKFIETYVQQVNPSKTAQVVGALLDMDCDEAFIQSLLQSVLGQVPINELTTEVE
KRNRLKILLPFLEQSLSQGIQDQAVYNALAKIYIDSNNSPEKFLKENDQYDTLDVGHY
CEKRDPYLAYIAYEKGQNDDDLIRITNENSMYKYQARYLLERSDLDLWNKVLNQENIH
RRQLIDSVISVGIPELTDPEPVSLTVQAFMTNGLKLELIELLEKIILEPSPFNENVAL
QGLLLLSAIKYEPTKVSSYIEKLDNYDADEIAPLCIEHDLKEEAFEIYDKHEMYGKAL
KVLIEDIMSLDRAASYADKINTPELWSQIGTAQLDGLRIPDAIESYIKAEDPSNYENV
IDIAEQAGKYEELIPFLLMARKTLKEPKIDGALILAYAELNKIHEIENLLAGSNVANL
DHVGDKLFENKEYKAARLCYSAVSNYSKLASTLVYLGDYQAAVDTARKASNIKVWKLV
NDACIEKKEFKLAQICGLNLIVHAEELDELVERYESNGYFEELISLFEAGLGLERAHM
GMFTELAILYSKYEPDKTFEHLKLFWSRINIPKVIRAVEQAHLWSELVFLYAHYDEWD
NAALTLIEKSTKDLDHAYFKEVVVKVSNLEIYYKAINFYVKFHPSLLVDLLTSLTPRL
DIPRTVKIFSKSDNLPLIKPFLINVLPKNNSVVNQAYHDLMIEEEDYKALQDAVDSYD
KFDQLGLASRLESHKLIFFKKIGALLYRRNKKWAKSLSILKEEKLWKDAIETAAISQD
PKVVEALLTYFVETGNREGFVALLYAAYNLVRIEFVLEISWMNSLEDYIKPFEISIKK
EQNDSIKKITEELAKKSGSNEEHKDGQPLMLMNSAMNVQPTGF"
gene 108158..110404
/gene="POX1"
/locus_tag="YGL205W"
/gene_synonym="FOX1"
/db_xref="GeneID:852667"
mRNA 108158..110404
/gene="POX1"
/locus_tag="YGL205W"
/gene_synonym="FOX1"
/product="acyl-CoA oxidase"
/transcript_id="NM_001181070.1"
/db_xref="GI:296144851"
/db_xref="GeneID:852667"
CDS 108158..110404
/gene="POX1"
/locus_tag="YGL205W"
/gene_synonym="FOX1"
/EC_number="1.3.3.6"
/note="Fatty-acyl coenzyme A oxidase, involved in the
fatty acid beta-oxidation pathway; localized to the
peroxisomal matrix"
/codon_start=1
/product="acyl-CoA oxidase"
/protein_id="NP_011310.1"
/db_xref="GI:6321233"
/db_xref="SGD:S000003173"
/db_xref="GeneID:852667"
/translation="MTRRTTINPDSVVLNPQKFIQKERADSKIKVDQVNTFLESSPER
RTLTHALIDQIVNDPILKTDTDYYDAKKMQEREITAKKIARLASYMEHDIKTVRKHFR
DTDLMKELQANDPDKASPLTNKDLFIFDKRLSLVANIDPQLGTRVGVHLGLFGNCIKG
NGTDEQIRYWLQERGATLMKGIYGCFAMTELGHGSNVAQLQTRAVYDKQNDTFVIDTP
DLTATKWWIGGAAHSATHAAVYARLIVEGKDYGVKTFVVPLRDPSTFQLLAGVSIGDI
GAKMGRDGIDNGWIQFRNVVIPREFMLSRFTKVVRSPDGSVTVKTEPQLDQISGYSAL
LSGRVNMVMDSFRFGSKFATIAVRYAVGRQQFAPRKGLSETQLIDYPLHQYRVLPQLC
VPYLVSPVAFKLMDNYYSTLDELYNASSSAYKAALVTVSKKLKNLFIDSASLKATNTW
LIATLIDELRQTCGGHGYSQYNGFGKGYDDWVVQCTWEGDNNVLSLTSAKSILKKFID
SATKGRFDNTLDVDSFSYLKPQYIGSVVSGEIKSGLKELGDYTEIWSITLIKLLAHIG
TLVEKSRSIDSVSKLLVLVSKFHALRCMLKTYYDKLNSRDSHISDEITKESMWNVYKL
FSLYFIDKHSGEFQQFKIFTPDQISKVVQPQLLALLPIVRKDCIGLTDSFELPDAMLN
SPIGYFDGDIYHNYFNEVCRNNPVEADGAGKPSYHALLSSMLGRGFEFDQKLGGAANA
EILSKINK"
gene complement(110625..110696)
/locus_tag="tH(GUG)G1"
/db_xref="GeneID:852668"
tRNA complement(110625..110696)
/locus_tag="tH(GUG)G1"
/product="tRNA-His"
/note="Histidine tRNA (tRNA-His), predicted by tRNAscan-SE
analysis"
/db_xref="SGD:S000006595"
/db_xref="GeneID:852668"
LTR 110855..111225
/note="Ty4 LTR"
/db_xref="SGD:S000006950"
LTR complement(111226..111505)
/note="Ty1 LTR"
/db_xref="SGD:S000006935"
LTR 111506..111698
/note="Ty1 LTR"
/db_xref="SGD:S000006940"
gene complement(111700..112005)
/locus_tag="YGL204C"
/db_xref="GeneID:852669"
mRNA complement(111700..112005)
/locus_tag="YGL204C"
/product="hypothetical protein"
/transcript_id="NM_001270746.1"
/db_xref="GI:398364270"
/db_xref="GeneID:852669"
CDS complement(111700..112005)
/locus_tag="YGL204C"
/note="hypothetical protein; mRNA identified as translated
by ribosome profiling data"
/codon_start=1
/product="hypothetical protein"
/protein_id="NP_001257675.1"
/db_xref="GI:398364271"
/db_xref="SGD:S000003172"
/db_xref="GeneID:852669"
/translation="MNGTDILRFLQSSPTISYSKHFILITACPLFVLGLLLLGLRTAM
FKQVRGKTTTSRNRGVIAAKLLVAWYLATIVMYIAKSEMWKYAFAVSLLLNSLALFF"
rep_origin 112079..112317
/note="ARS704;
Autonomously Replicating Sequence"
/db_xref="SGD:S000118452"
gene complement(112475..114664)
/gene="KEX1"
/locus_tag="YGL203C"
/db_xref="GeneID:852670"
mRNA complement(112475..114664)
/gene="KEX1"
/locus_tag="YGL203C"
/product="Kex1p"
/transcript_id="NM_001181068.1"
/db_xref="GI:296144852"
/db_xref="GeneID:852670"
CDS complement(112475..114664)
/gene="KEX1"
/locus_tag="YGL203C"
/EC_number="3.4.16.6"
/note="Protease involved in the processing of killer toxin
and alpha factor precursor; cleaves Lys and Arg residues
from the C-terminus of peptides and proteins"
/codon_start=1
/product="Kex1p"
/protein_id="NP_011312.1"
/db_xref="GI:6321235"
/db_xref="SGD:S000003171"
/db_xref="GeneID:852670"
/translation="MFYNRWLGTWLAMSALIRISVSLPSSEEYKVAYELLPGLSEVPD
PSNIPQMHAGHIPLRSEDADEQDSSDLEYFFWKFTNNDSNGNVDRPLIIWLNGGPGCS
SMDGALVESGPFRVNSDGKLYLNEGSWISKGDLLFIDQPTGTGFSVEQNKDEGKIDKN
KFDEDLEDVTKHFMDFLENYFKIFPEDLTRKIILSGESYAGQYIPFFANAILNHNKFS
KIDGDTYDLKALLIGNGWIDPNTQSLSYLPFAMEKKLIDESNPNFKHLTNAHENCQNL
INSASTDEAAHFSYQECENILNLLLSYTRESSQKGTADCLNMYNFNLKDSYPSCGMNW
PKDISFVSKFFSTPGVIDSLHLDSDKIDHWKECTNSVGTKLSNPISKPSIHLLPGLLE
SGIEIVLFNGDKDLICNNKGVLDTIDNLKWGGIKGFSDDAVSFDWIHKSKSTDDSEEF
SGYVKYDRNLTFVSVYNASHMVPFDKSLVSRGIVDIYSNDVMIIDNNGKNVMITTDDD
SDQDATTESGDKPKENLEEEEQEAQNEEGKEKEGNKDKDGDDDNDNDDDDEDDHNSEG
DDDDDDDDDEDDNNEKQSNQGLEDSRHKSSEYEQEEEEVEEFAEEISMYKHKAVVVTI
VTFLIVVLGVYAYDRRVRRKARHTILVDPNNRQHDSPNKTVSWADDLESGLGAEDDLE
QDEQLEGGAPISSTSNKAGSKLKTKKKKKYTSLPNTEIDESFEMTDF"
LTR 114939..115269
/note="Ty1 LTR"
/db_xref="SGD:S000006941"
gene 115488..115583
/locus_tag="tK(UUU)G1"
/db_xref="GeneID:852671"
tRNA join(115488..115524,115548..115583)
/locus_tag="tK(UUU)G1"
/product="tRNA-Lys"
/note="Lysine tRNA (tRNA-Lys), predicted by tRNAscan-SE
analysis; thiolation of uridine at wobble position (34)
requires Ncs6p"
/db_xref="SGD:S000006630"
/db_xref="GeneID:852671"
gene 116059..117561
/gene="ARO8"
/locus_tag="YGL202W"
/db_xref="GeneID:852672"
mRNA 116059..117561
/gene="ARO8"
/locus_tag="YGL202W"
/product="bifunctional 2-aminoadipate
transaminase/aromatic-amino-acid:2-oxoglutarate
transaminase"
/transcript_id="NM_001181067.1"
/db_xref="GI:296144853"
/db_xref="GeneID:852672"
CDS 116059..117561
/gene="ARO8"
/locus_tag="YGL202W"
/EC_number="2.6.1.39"
/EC_number="2.6.1.27"
/EC_number="2.6.1.5"
/note="Aromatic aminotransferase I, expression is
regulated by general control of amino acid biosynthesis"
/codon_start=1
/product="bifunctional 2-aminoadipate
transaminase/aromatic-amino-acid:2-oxoglutarate
transaminase"
/protein_id="NP_011313.1"
/db_xref="GI:6321236"
/db_xref="SGD:S000003170"
/db_xref="GeneID:852672"
/translation="MTLPESKDFSYLFSDETNARKPSPLKTCIHLFQDPNIIFLGGGL
PLKDYFPWDNLSVDSPKPPFPQGIGAPIDEQNCIKYTVNKDYADKSANPSNDIPLSRA
LQYGFSAGQPELLNFIRDHTKIIHDLKYKDWDVLATAGNTNAWESTLRVFCNRGDVIL
VEAHSFSSSLASAEAQGVITFPVPIDADGIIPEKLAKVMENWTPGAPKPKLLYTIPTG
QNPTGTSIADHRKEAIYKIAQKYDFLIVEDEPYYFLQMNPYIKDLKEREKAQSSPKQD
HDEFLKSLANTFLSLDTEGRVIRMDSFSKVLAPGTRLGWITGSSKILKPYLSLHEMTI
QAPAGFTQVLVNATLSRWGQKGYLDWLLGLRHEYTLKRDCAIDALYKYLPQSDAFVIN
PPIAGMFFTVNIDASVHPEFKTKYNSDPYQLEQSLYHKVVERGVLVVPGSWFKSEGET
EPPQPAESKEVSNPNIIFFRGTYAAVSPEKLTEGLKRLGDTLYEEFGISK"
rep_origin 117561..117854
/note="ARS706;
Autonomously Replicating Sequence"
/db_xref="SGD:S000114845"
gene complement(117854..120907)
/gene="MCM6"
/locus_tag="YGL201C"
/db_xref="GeneID:852673"
mRNA complement(117854..120907)
/gene="MCM6"
/locus_tag="YGL201C"
/product="Mcm6p"
/transcript_id="NM_001181066.1"
/db_xref="GI:296144854"
/db_xref="GeneID:852673"
CDS complement(117854..120907)
/gene="MCM6"
/locus_tag="YGL201C"
/note="Protein involved in DNA replication; component of
the Mcm2-7 hexameric complex that binds chromatin as a
part of the pre-replicative complex; forms a subcomplex
with Mcm4p and Mcm7p"
/codon_start=1
/product="Mcm6p"
/protein_id="NP_011314.2"
/db_xref="GI:41629691"
/db_xref="SGD:S000003169"
/db_xref="GeneID:852673"
/translation="MSSPFPADTPSSNRPSNSSPPPSSIGAGFGSSSGLDSQIGSRLH
FPSSSQPHVSNSQTGPFVNDSTQFSSQRLQTDGSATNDMEGNEPARSFKSRALNHVKK
VDDVTGEKVREAFEQFLEDFSVQSTDTGEVEKVYRAQIEFMKIYDLNTIYIDYQHLSM
RENGALAMAISEQYYRFLPFLQKGLRRVVRKYAPELLNTSDSLKRSEGDEGQADEDEQ
QDDDMNGSSLPRDSGSSAAPGNGTSAMATRSITTSTSPEQTERVFQISFFNLPTVHRI
RDIRSEKIGSLLSISGTVTRTSEVRPELYKASFTCDMCRAIVDNVEQSFKYTEPTFCP
NPSCENRAFWTLNVTRSRFLDWQKVRIQENANEIPTGSMPRTLDVILRGDSVERAKPG
DRCKFTGVEIVVPDVTQLGLPGVKPSSTLDTRGISKTTEGLNSGVTGLRSLGVRDLTY
KISFLACHVISIGSNIGASSPDANSNNRETELQMAANLQANNVYQDNERDQEVFLNSL
SSDEINELKEMVKDEHIYDKLVRSIAPAVFGHEAVKKGILLQMLGGVHKSTVEGIKLR
GDINICVVGDPSTSKSQFLKYVVGFAPRSVYTSGKASSAAGLTAAVVRDEEGGDYTIE
AGALMLADNGICCIDEFDKMDISDQVAIHEAMEQQTISIAKAGIHATLNARTSILAAA
NPVGGRYNRKLSLRGNLNMTAPIMSRFDLFFVILDDCNEKIDTELASHIVDLHMKRDE
AIEPPFSAEQLRRYIKYARTFKPILTKEARSYLVEKYKELRKDDAQGFSRSSYRITVR
QLESMIRLSEAIARANCVDEITPSFIAEAYDLLRQSIIRVDVDDVEMDEEFDNIESQS
HAASGNNDDNDDGTGSGVITSEPPADIEEGQSEATARPGTSEKKKTTVTYDKYVSMMN
MIVRKIAEVDREGAEELTAVDIVDWYLLQKENDLGSLAEYWEERRLAFKVIKRLVKDR
ILMEIHGTRHNLRDLENEENENNKTVYVIHPNCEVLDQLEPQDSS"
gene 122269..122341
/locus_tag="tK(CUU)G1"
/db_xref="GeneID:852674"
tRNA 122269..122341
/locus_tag="tK(CUU)G1"
/product="tRNA-Lys"
/note="Lysine tRNA (tRNA-Lys), predicted by tRNAscan-SE
analysis; a small portion is imported into mitochondria
via interaction with mt lysyl-tRNA synthetase Msk1p and is
necessary to decode AAG codons at high temperature, when
base modification of mt-encoded tRNA-Lys is reduced"
/db_xref="SGD:S000006621"
/db_xref="GeneID:852674"
gene complement(122694..123305)
/gene="EMP24"
/locus_tag="YGL200C"
/gene_synonym="BST2"
/db_xref="GeneID:852675"
mRNA complement(122694..123305)
/gene="EMP24"
/locus_tag="YGL200C"
/gene_synonym="BST2"
/product="Emp24p"
/transcript_id="NM_001181065.3"
/db_xref="GI:398364280"
/db_xref="GeneID:852675"
CDS complement(122694..123305)
/gene="EMP24"
/locus_tag="YGL200C"
/gene_synonym="BST2"
/note="Component of the p24 complex; binds to GPI anchor
proteins and mediates their efficient transport from the
ER to the Golgi; integral membrane protein that associates
with endoplasmic reticulum-derived COPII-coated vesicles"
/codon_start=1
/product="Emp24p"
/protein_id="NP_011315.3"
/db_xref="GI:398364281"
/db_xref="SGD:S000003168"
/db_xref="GeneID:852675"
/translation="MASFATKFVIACFLFFSASAHNVLLPAYGRRCFFEDLSKGDELS
ISFQFGDRNPQSSSQLTGDFIIYGPERHEVLKTVRDTSHGEITLSAPYKGHFQYCFLN
ENTGIETKDVTFNIHGVVYVDLDDPNTNTLDSAVRKLSKLTREVKDEQSYIVIRERTH
RNTAESTNDRVKWWSIFQLGVVIANSLFQIYYLRRFFEVTSLV"
gene 123591..124298
/gene="YIP4"
/locus_tag="YGL198W"
/db_xref="GeneID:852676"
mRNA 123591..124298
/gene="YIP4"
/locus_tag="YGL198W"
/product="Yip4p"
/transcript_id="NM_001181063.1"
/db_xref="GI:296144856"
/db_xref="GeneID:852676"
CDS 123591..124298
/gene="YIP4"
/locus_tag="YGL198W"
/note="Protein that interacts with Rab GTPases, localized
to late Golgi vesicles; computational analysis of
large-scale protein-protein interaction data suggests a
possible role in vesicle-mediated transport"
/codon_start=1
/product="Yip4p"
/protein_id="NP_011317.2"
/db_xref="GI:41629692"
/db_xref="SGD:S000003166"
/db_xref="GeneID:852676"
/translation="MSYGREDTTIEPDFIEPDAPLAASGGVADNIGGTMQNSGSRGTL
DETVLQTLKRDVVEINSRLKQVVYPHFPSFFSPSDDGIGAADNDISANCDLWAPLAFI
ILYSLFVSHARSLFSSLFVSSWFILLVMALHLRLTKPHQRVSLISYISISGYCLFPQV
LNALVSQILLPLAYHIGKQNRWIVRVLSLVKLVVMALCLMWSVAAVSWVTKSKTIIEI
YPLALCLFGMAWLSTIL"
gene 124698..129161
/gene="MDS3"
/locus_tag="YGL197W"
/db_xref="GeneID:852678"
mRNA 124698..129161
/gene="MDS3"
/locus_tag="YGL197W"
/product="Mds3p"
/transcript_id="NM_001181062.2"
/db_xref="GI:330443545"
/db_xref="GeneID:852678"
CDS 124698..129161
/gene="MDS3"
/locus_tag="YGL197W"
/note="Putative component of the TOR regulatory pathway;
negative regulator of early meiotic gene expression;
required, with Pmd1p, for growth under alkaline
conditions; has an N-terminal kelch-like domain"
/codon_start=1
/product="Mds3p"
/protein_id="NP_011318.2"
/db_xref="GI:330443546"
/db_xref="SGD:S000003165"
/db_xref="GeneID:852678"
/translation="MPLLQPSTCFCYPLKLPPLPLTSDSNEFDECARKRLTLDYRTGS
AVTLTRSNIFVHGGLTIPLNLPVVNSMQLQKELILFFAKEKNNGSSFRNLNEWISKET
FFLDLMSRTWYRVKTSFDQRTEELLKAESSSAKADNDTNEIRTDIKKGKSLESPLKER
LFHSLCYLDGCLYIFGGLTVSPQSGYELIATNELWKLDLNTKKWSLLSDDPQIARRFN
HTMHVKNENNDNRDTKLIIVGGLNNMDQPVKKIDIYNISQNCWQSETIPKQPMEITTN
VNGIPLALSKDQNFSILVENNEANVPALAFYMRSDQIDEYLGKDSSKIKENSPIVALP
LLSESQGIRMPSNPALPKKLLNVPYELLAPTGDYFGFNIIIGGFHPNYQSSNFHCFIY
DINSGKWSRVATACPDCDINKHRFWRVFVWKSHHQTILLGTKTDDYYSPSVQRFDHLS
TFGLPLVNIFNKTIQLPHHKISASSLPIPIENFAKHKDTPLKKVSFTSSATSQFENYI
RYIAPPLEMSSIQSVFPPYAMVLGKDALEIYGKPLSDFEFITSEGDSIGIPCYLLRKR
WGRYFDMLLSQSYTKVCADYETTDTQSTLIKFSPHSSRNSSKAVRQEGRLSSSGSLDN
YFEKNFPIFARTSVSEAQNTQPQVANADAKAPNTPSTSDEPSSSSSSDLYSTPHYQRN
NDEEDDEDPVSPKPVSKSNSIYRPIRKTESSSTTSSSNGMIFRVPFKEKAAVTSNTEA
LLESNLSLQELSRRRSSLMSIPSGELLRSSISEAEHQRRASHPLTSSPLFEDSGTPCG
KQLQQLQQHTIQNPHNHLSPRRFSRSARSSISYVSSSSDRRGNSISSRSTSDSFGTPP
VLGVLNVPLPPQTREPNEPPPPCPAMSTGSNTRRSNTLTDYMHSNKASPFSSRRSSHI
GRRSSTPETENAFSATPRASLDGQMLGKSLKEGSTSQYTQPRMNSFPKANETIQTPTS
SNNEWSRQSVTSNTDSFDSLQSNFALELEPLLTPRSLYMPWPTSTVRAFAEFFYTGQV
NSKWLLAPVALDLLVMAKIYEIPLLYKLILEVLYSILAKKEESLSLICTSLMETFRTK
TLNSYKGDEEKTNTYLTSNDNYQELLKLKVSLENIDNGYYDPDLLRKQSRAQSSSTQE
SSGSANGEKTATGAGSLETSSTNVPTVFAGGPRDSHNSVGSIGFPNSMNIQGSRRSTS
GFSPRVKMKSSLSKEIDPKTFYEEYEPKEGKSFDDNDDQQTNIGSFNLHLFDMNYGSI
SSSSTNSISSSDLEEKEEQEQLQDLLEIEREDSAEILDARFRNKEDDKVTKDISNDKK
RNYLPHEKNNLKAKEGKETRDVREEEEEFDFGLGMLSLNKIKREAKHVDKVDDSVDPL
FKSSAFPQSPIRAYGSTTRTSSASGKPFRDNRSFNAFSVLTLENMASANALPPVDYVI
KSIYRTTVLVNDIRLMVRCMDCIELSKNLRALKKKTMEDISKLKGISKPSP"
gene 129883..131169
/gene="DSD1"
/locus_tag="YGL196W"
/db_xref="GeneID:852679"
mRNA 129883..131169
/gene="DSD1"
/locus_tag="YGL196W"
/product="D-serine ammonia-lyase DSD1"
/transcript_id="NM_001181061.1"
/db_xref="GI:296144858"
/db_xref="GeneID:852679"
CDS 129883..131169
/gene="DSD1"
/locus_tag="YGL196W"
/note="D-serine dehydratase (aka D-serine ammonia-lyase);
converts D-serine to pyruvate and ammonia by a reaction
dependent on pyridoxal 5'-phosphate and zinc; may play a
role in D-serine detoxification; L-serine is not a
substrate"
/codon_start=1
/product="D-serine ammonia-lyase DSD1"
/protein_id="NP_011319.2"
/db_xref="GI:50593216"
/db_xref="SGD:S000003164"
/db_xref="GeneID:852679"
/translation="MSDVLSQYKGCSVRDLPTPNFVINEEKFDKNCTTMLNNVEKLSQ
ECGVPIKFRAHVKTHKTAKGTLKQLGHGLPLAKRTTRAILVSTLKEAEELLNYQDRQC
SDYIDDITYSLPCCVPEFIPLLSNLSRRVNNFQVFVDNIEHLENLKNFGRPASGKKWS
VFIKVDMGTKRAGLAFDSPEFLSLLKKLTSSEIKEVIEPYGFYAHAGHSYSSTSINDT
QNLLMEEVKAVNSAAKVLCSVDPQFDPSKLTLSVGATPTSNSLKLDNKSTLVKFITTQ
LVSTLEIHCGNYCMYDLQQVATGCVQDHELSGFVLGTVLSSYPSRGELLSNTGVMCLT
REASSIKGFGICADLEHVLKSESFSREWYVARVSQEHGILRPIRNWNETTPLKLGSKI
AVLPQHACITMGQFPYYFVVNSEGIVNDVWLPFQKW"
gene 131525..139543
/gene="GCN1"
/locus_tag="YGL195W"
/gene_synonym="AAS103; NDR1"
/db_xref="GeneID:852680"
mRNA 131525..139543
/gene="GCN1"
/locus_tag="YGL195W"
/gene_synonym="AAS103; NDR1"
/product="Gcn1p"
/transcript_id="NM_001181060.3"
/db_xref="GI:398364286"
/db_xref="GeneID:852680"
CDS 131525..139543
/gene="GCN1"
/locus_tag="YGL195W"
/gene_synonym="AAS103; NDR1"
/note="Positive regulator of the Gcn2p kinase activity,
forms a complex with Gcn20p; proposed to stimulate Gcn2p
activation by an uncharged tRNA"
/codon_start=1
/product="Gcn1p"
/protein_id="NP_011320.3"
/db_xref="GI:398364287"
/db_xref="SGD:S000003163"
/db_xref="GeneID:852680"
/translation="MTAILNWEDISPVLEKGTRESHVSKRVPFLQDISQLVRQETLEK
PQLSEIAFVLLNTFTIYEDNRSKSLVTSILLDILNLEPCLLENFIRFISDVVISNPAT
KAVADYLNLLDWINSFLIFVSHNSNLFEEYIPKLLVAHSYATFGVETILDNQEEGKKS
QDKQNQHRKRIRYCIFQTTVKAFLKCLKDNDDSISFMKISIKTVLESYSKLKITSVGV
VMIMGALTQAALQLLSRQPALHSVLKENSAEKYCEYLGKEVFLGKNPPSSFCLEIGLK
PFLKEFVSQELFIKFFIPNIEKAVLRSPEVGFSILSELYAGVSPEKVNLLNAFASSKL
INQYFSSFKSSKEVVRSVSLQSMIILLRKISNTDTTLEDLTKLIDEIFKNIKSNLNAD
YKSLISKILIEIPLTHYEVSEKICKGLSPYIGKEGNEAALTLMLNAFFVHYFSLGKPI
EDLDKIISAGFADKKPALKKCWFAAFLNNSNAASEEVILNFIDGCLEFVKDSIIHYQT
HGHACILASIEFTNKILALDNTELNDRVMQLIETLPENSSIGDAILTAALSTELSIEN
RIHAVNLLQELFYKKPEFIGFSVIDAIERRMRVQELIPQQNTSFKYVTSVLLAITSEL
PDKEASIKVLINALVIAQWNIFNIKNGWAGLVLRARLDPAEVVKEHASVIMEKILEIT
GSCEWIDTIYGACGLQAAAYAAFIQPNEFTPILCKTIEADLTADDFSRLSEEDFEIFA
GEEGVLVVDVLEESMNKKLSNKNSKEYETLMWEQKIRKEQAKKNVKKLSKEEQELVNE
QLAKESAVRSHVSEISTRLKRGIRLVSELSKAACLVQNGIATWFPLAVTKLLYLCSEP
NISKLTEDVNNVFLQLSQNVSERLGNIRLFLGLATLRVHNANGISQDYLQEPLVELLT
RVLFRIKFVSNQAAIDSISLTYILPLLINVLEKGKAIALKNADKPVVKAEFVEEDEEE
EHLLLAMEIISVHAEAFEDPSIPRISIVEVLLSLLSLPSKAKIAKDCFNALCQSISVA
PNQEDLDMILSNLLSPNQFVRSTILETLDNEFELEPFMKYSPEVFICRFDSDPSNREI
ADFIWEFNKFVVNDELLKSLFPLFNQDDSGLRLFAANAYAFGAVSLFTSEENSSKDYL
NDLLNFYKEKAKPLEPILDQFGLVLVSASEQKDPWQGRSTVAITLKIMAKAFSAEDDT
VVNIIKFLVDDGGLVDREPIVRQEMKEAGVELITLHGSQNSKDLIPIFEEALSSSTDS
ALKENVIILYGTLARHLQQSDARIHTIIERLLSTLDTPSADIQQAVSACIAPLVFQFK
QKVGDYLGILMEKLLNPTVASSMRKGAAWGIAGLVKGYGISALSEFDIIRNLIEAAED
KKEPKRRESVGFCFQYLSESLGKFFEPYVIEILPNILKNLGDAVPEVRDATARATKAI
MAHTTGYGVKKLIPVAVSNLDEIAWRTKRGSVQLLGNMAYLDPTQLSASLSTIVPEIV
GVLNDSHKEVRKAADESLKRFGEVIRNPEIQKLVPVLLQAIGDPTKYTEEALDSLIQT
QFVHYIDGPSLALIIHIIHRGMHDRSANIKRKACKIVGNMAILVDTKDLIPYLQQLID
EVEIAMVDPVPNTRATAARALGALVERLGEEQFPDLIPRLLDTLSDESKSGDRLGSAQ
ALAEVISGLGLTKLDEMLPTILAGVTNFRAYIREGFMPLLLFLPVCFGSQFAPYINQI
IQPILSGLADNDENIRDTALKAGKLIVKNYATKAVDLLLPELERGMFDENDRIRLSSV
QLTGELLFQVTGISSRNEFSEEDGDHNGEFSGKLVDVLGQDRRDRILAALFVCRNDTS
GIVRATTVDIWKALVPNTPRAVKEILPTLTGMIVTHLASSSNVLRNIAAQTLGDLVRR
VGGNALSQLLPSLEESLIETSNSDSRQGVCIALYELIESASTETISQFQSTIVNIIRT
ALIDESATVREAAALSFDVFQDVVGKTAVDEVLPYLLHMLESSDNSDFALLGLQEIMS
KKSDVIFPILIPTLLAPPIDAFRASALGSLAEVAGSALYKRLSIIINALVDAIIGTSE
DESTKGALELALDRVFLSVNDDEGLHPLLQQIMSLLKSDNIEKRIAVLERLPNFFDKT
VLDFDVYIPNFVSHAILSLDDEDQRVVNGNFNALSTLLKKVDKPTLEKLVKPAKQSLA
LTGRQGQDVAAFKLPRGPNCVLPIFLHGLMYGSNDEREESALAIADVVSKTPAANLKP
FVSVITGPLIRVVGERFSSDIKAAILFALNVLFIKIPMFLRPFIPQLQRTFVKSLSDA
TNETLRLRAAKALGALIEHQPRVDPLVIELVTGAKQATDEGVKTAMLKALLEVIMKAG
SKLNENSKTNIVNLVEEEMLGSNDKLAVAYAKLIGSLSEILSNDEAHKILQDKVLNAD
LDGETGKFAILTLNSFLKDAPTHIFNTGLIDEFVSYILNAIRSPDVYFGENGTIAAGK
LLLLEGEKRSPFVKKDAAEPFKIGDENINLLINELSKAVLQPASNSTDVRRLALVVIR
TLARFKFDECIKQYFDVVGPSVFSCLRDPVIPIKLAAEKAYLALFKLVEEDDMHTFNE
WFAKISDRGNSIETVTGTTIQLRSVGDYTKRVGKRLANVERERIAAGGDAETMFSDRF
EDEREIWAVGGVELTTDI"
gene complement(139719..139961)
/locus_tag="YGL194C-A"
/db_xref="GeneID:3799973"
mRNA complement(139719..139961)
/locus_tag="YGL194C-A"
/product="hypothetical protein"
/transcript_id="NM_001184677.1"
/db_xref="GI:296144860"
/db_xref="GeneID:3799973"
CDS complement(139719..139961)
/locus_tag="YGL194C-A"
/note="hypothetical protein, identified based on
comparisons of the genome sequences of six Saccharomyces
species"
/codon_start=1
/product="hypothetical protein"
/protein_id="NP_001032578.1"
/db_xref="GI:82795250"
/db_xref="SGD:S000087160"
/db_xref="GeneID:3799973"
/translation="MSNKEITCIKPFKIIALILLIVLIINLSYKLFLRRYLKSTVIWC
LGIANTDRNDMMWWQVSPLLERWVWQLVDNYESGYE"
gene complement(140368..141726)
/gene="HOS2"
/locus_tag="YGL194C"
/gene_synonym="RTL1"
/db_xref="GeneID:852681"
mRNA complement(140368..141726)
/gene="HOS2"
/locus_tag="YGL194C"
/gene_synonym="RTL1"
/product="Hos2p"
/transcript_id="NM_001181059.1"
/db_xref="GI:296144861"
/db_xref="GeneID:852681"
CDS complement(140368..141726)
/gene="HOS2"
/locus_tag="YGL194C"
/gene_synonym="RTL1"
/note="Histone deacetylase and subunit of Set3 and Rpd3L
complexes; required for gene activation via specific
deacetylation of lysines in H3 and H4 histone tails;
subunit of the Set3 complex, a meiotic-specific repressor
of sporulation specific genes that contains deacetylase
activity; co-localizes with Cmr1p in nuclear foci in
response to DNA damage by MMS"
/codon_start=1
/product="Hos2p"
/protein_id="NP_011321.1"
/db_xref="GI:6321244"
/db_xref="SGD:S000003162"
/db_xref="GeneID:852681"
/translation="MSGTFSYDVKTKENEPLFEFNSAYSPRVSYHFNSKVSHYHYGVK
HPMKPFRLMLTDHLVSSYGLHKIMDLYETRSATRDELLQFHSEDYVNFLSKVSPENAN
KLPRGTLENFNIGDDCPIFQNLYDYTTLYTGASLDATRKLINNQSDIAINWSGGLHHA
KKNSPSGFCYVNDIVLSILNLLRYHPRILYIDIDLHHGDGVQEAFYTTDRVFTLSFHK
YNGEFFPGTGDLTEIGCDKGKHFALNVPLEDGIDDDSYINLFKSIVDPLIMTFKPTLI
VQQCGADSLGHDRLGCFNLNIKAHGECVKFVKSFGLPMLVVGGGGYTPRNVSRLWTYE
TGILNDVLLPEDIPEDIPFRDSFGPDYSLYPMLDDLYENKNSKKLLEDIRIRCLENIR
YLQGAPSVRMDAECIPTQDISALTEEEDKIIQEMNEETEADSSNRLEEMEKENSGLIA
FS"
gene complement(141916..142227)
/locus_tag="YGL193C"
/db_xref="GeneID:852682"
mRNA complement(141916..142227)
/locus_tag="YGL193C"
/product="hypothetical protein"
/transcript_id="NM_001181058.1"
/db_xref="GI:296144862"
/db_xref="GeneID:852682"
CDS complement(141916..142227)
/locus_tag="YGL193C"
/note="Haploid-specific gene repressed by a1-alpha2,
turned off in sir3 null strains, absence enhances the
sensitivity of rad52-327 cells to campothecin almost
100-fold"
/codon_start=1
/product="hypothetical protein"
/protein_id="NP_011322.1"
/db_xref="GI:6321245"
/db_xref="SGD:S000003161"
/db_xref="GeneID:852682"
/translation="MNSSLNANSYFFRKPPMLTYMVRFLYCYPSPFPIAPAVTDLPEC
RGDLSLSLFITSFTSTKERTILYAKSRLKTHIPVNLCDRYHYIPKAPLYQCRMPCLYS
I"
gene 142246..144048
/gene="IME4"
/locus_tag="YGL192W"
/gene_synonym="SPO8"
/db_xref="GeneID:852683"
mRNA 142246..144048
/gene="IME4"
/locus_tag="YGL192W"
/gene_synonym="SPO8"
/product="Ime4p"
/transcript_id="NM_001181057.3"
/db_xref="GI:398364296"
/db_xref="GeneID:852683"
CDS 142246..144048
/gene="IME4"
/locus_tag="YGL192W"
/gene_synonym="SPO8"
/EC_number="2.1.1.62"
/note="Probable mRNA N6-adenosine methyltransferase
required for entry into meiosis; transcribed in diploid
cells; haploids repress IME4 transcription via production
of antisense IME4 transcripts; antisense transcription is
repressed in diploids"
/codon_start=1
/product="Ime4p"
/protein_id="NP_011323.3"
/db_xref="GI:398364297"
/db_xref="SGD:S000003160"
/db_xref="GeneID:852683"
/translation="MINDKLVHFLIQNYDDILRAPLSGQLKDVYSLYISGGYDDEMQK
LRNDKDEVLQFEQFWNDLQDIIFATPQSIQFDQNLLVADRPEKIVYLDVFSLKILYNK
FHAFYYTLKSSSSSCEEKVSSLTTKPEADSEKDQLLGRLLGVLNWDVNVSNQGLPREQ
LSNRLQNLLREKPSSFQLAKERAKYTTEVIEYIPICSDYSHASLLSTSVYIVNNKIVS
LQWSKISACQENHPGLIECIQSKIHFIPNIKPQTDISLGDCSYLDTCHKLNTCRYIHY
LQYIPSCLQERADRETASENKRIRSNVSIPFYTLGNCSAHCIKKALPAQWIRCDVRKF
DFRVLGKFSVVIADPAWNIHMNLPYGTCNDIELLGLPLHELQDEGIIFLWVTGRAIEL
GKESLNNWGYNVINEVSWIKTNQLGRTIVTGRTGHWLNHSKEHLLVGLKGNPKWINKH
IDVDLIVSMTRETSRKPDELYGIAERLAGTHARKLEIFGRDHNTRPGWFTIGNQLTGN
CIYEMDVERKYQEFMKSKTGTSHTGTKKIDKKQPSKLQQQHQQQYWNNMDMGSGKYYA
EAKQNPMNQKHTPFESKQQQKQQFQTLNNLYFAQ"
gene 144808..145197
/gene="COX13"
/locus_tag="YGL191W"
/db_xref="GeneID:852684"
mRNA 144808..145197
/gene="COX13"
/locus_tag="YGL191W"
/product="cytochrome c oxidase subunit VIa"
/transcript_id="NM_001181056.1"
/db_xref="GI:296144864"
/db_xref="GeneID:852684"
CDS 144808..145197
/gene="COX13"
/locus_tag="YGL191W"
/EC_number="1.9.3.1"
/note="Subunit VIa of cytochrome c oxidase; present in a
subclass of cytochrome c oxidase complexes that may have a
role in mimimizing generation of reactive oxygen species;
not essential for cytochrome c oxidase activity but may
modulate activity in response to ATP; required for
assembly of Rcf2p into cytochrome c oxidase - cytochrome
bc1 supercomplexes"
/codon_start=1
/product="cytochrome c oxidase subunit VIa"
/protein_id="NP_011324.1"
/db_xref="GI:6321247"
/db_xref="SGD:S000003159"
/db_xref="GeneID:852684"
/translation="MFRQCAKRYASSLPPNALKPAFGPPDKVAAQKFKESLMATEKHA
KDTSNMWVKISVWVALPAIALTAVNTYFVEKEHAEHREHLKHVPDSEWPRDYEFMNIR
SKPFFWGDGDKTLFWNPVVNRHIEHDD"
gene complement(145809..147389)
/gene="CDC55"
/locus_tag="YGL190C"
/db_xref="GeneID:852685"
mRNA complement(145809..147389)
/gene="CDC55"
/locus_tag="YGL190C"
/product="Cdc55p"
/transcript_id="NM_001181055.1"
/db_xref="GI:296144865"
/db_xref="GeneID:852685"
CDS complement(145809..147389)
/gene="CDC55"
/locus_tag="YGL190C"
/note="Non-essential regulatory subunit B of protein
phosphatase 2A (PP2A); localization to the cytoplasm
requires Zds1p and Zds2p and promotes mitotic entry;
localization to the nucleus prevents mitotic exit;
required for correct nuclear division and chromosome
segregation in meiosis; maintains nucleolar sequestration
of Cdc14p during early meiosis; limits formation of
PP2A-Rts1p holocomplexes to ensure timely dissolution of
sister chromosome cohesion"
/codon_start=1
/product="Cdc55p"
/protein_id="NP_011325.1"
/db_xref="GI:6321248"
/db_xref="SGD:S000003158"
/db_xref="GeneID:852685"
/translation="MAQNNFDFKFSQCFGDKADIVVTEADLITAVEFDYTGNYLATGD
KGGRVVLFERSNSRHCEYKFLTEFQSHDAEFDYLKSLEIEEKINEIKWLRPTQRSHFL
LSTNDKTIKLWKVYEKNIKLVSQNNLTEGVTFAKKGKPDNHNSRGGSVRAVLSLQSLK
LPQLSQHDKIIAATPKRIYSNAHTYHINSISLNSDQETFLSADDLRINLWNLDIPDQS
FNIVDIKPTNMEELTEVITSAEFHPQECNLFMYSSSKGTIKLCDMRQNSLCDNKTKTF
EEYLDPINHNFFTEITSSISDIKFSPNGRYIASRDYLTVKIWDVNMDNKPLKTINIHE
QLKERLSDTYENDAIFDKFEVNFSGDSSSVMTGSYNNNFMIYPNVVTSGDNDNGIVKT
FDEHNAPNSNSNKNIHNSIQNKDSSSSGNSHKRRSNGRNTGMVGSSNSSRSSIAGGEG
ANSEDSGTEMNEIVLQADKTAFRNKRYGSLAQRSARNKDWGDDIDFKKNILHFSWHPR
ENSIAVAATNNLFIFSAL"
gene complement(148229..148588)
/gene="RPS26A"
/locus_tag="YGL189C"
/gene_synonym="RPS26"
/db_xref="GeneID:852686"
mRNA complement(148229..148588)
/gene="RPS26A"
/locus_tag="YGL189C"
/gene_synonym="RPS26"
/product="ribosomal 40S subunit protein S26A"
/transcript_id="NM_001181054.1"
/db_xref="GI:296144866"
/db_xref="GeneID:852686"
CDS complement(148229..148588)
/gene="RPS26A"
/locus_tag="YGL189C"
/gene_synonym="RPS26"
/note="Protein component of the small (40S) ribosomal
subunit; homologous to mammalian ribosomal protein S26, no
bacterial homolog; RPS26A has a paralog, RPS26B, that
arose from the whole genome duplication"
/codon_start=1
/product="ribosomal 40S subunit protein S26A"
/protein_id="NP_011326.1"
/db_xref="GI:6321249"
/db_xref="SGD:S000003157"
/db_xref="GeneID:852686"
/translation="MPKKRASNGRNKKGRGHVKPVRCVNCSKSIPKDKAIKRMAIRNI
VEAAAVRDLSEASVYPEYALPKTYNKLHYCVSCAIHARIVRVRSREDRKNRAPPQRPR
FNRENKVSPADAAKKAL"
gene complement(148824..148964)
/locus_tag="YGL188C-A"
/db_xref="GeneID:1466453"
mRNA complement(148824..148964)
/locus_tag="YGL188C-A"
/product="hypothetical protein"
/transcript_id="NM_001184593.3"
/db_xref="GI:398364302"
/db_xref="GeneID:1466453"
CDS complement(148824..148964)
/locus_tag="YGL188C-A"
/codon_start=1
/product="hypothetical protein"
/protein_id="NP_878073.3"
/db_xref="GI:398364303"
/db_xref="SGD:S000028635"
/db_xref="GeneID:1466453"
/translation="MLTTQKCESREGKNDEIFELGESNSDKILLKHGKCNLFSERKPV
NH"
gene complement(149704..150171)
/gene="COX4"
/locus_tag="YGL187C"
/db_xref="GeneID:852688"
mRNA complement(149704..150171)
/gene="COX4"
/locus_tag="YGL187C"
/product="cytochrome c oxidase subunit IV"
/transcript_id="NM_001181052.1"
/db_xref="GI:296144868"
/db_xref="GeneID:852688"
CDS complement(149704..150171)
/gene="COX4"
/locus_tag="YGL187C"
/EC_number="1.9.3.1"
/note="Subunit IV of cytochrome c oxidase, the terminal
member of the mitochondrial inner membrane electron
transport chain; precursor N-terminal 25 residues are
cleaved during mitochondrial import; phosphorylated;
spermidine enhances translation"
/codon_start=1
/product="cytochrome c oxidase subunit IV"
/protein_id="NP_011328.1"
/db_xref="GI:6321251"
/db_xref="SGD:S000003155"
/db_xref="GeneID:852688"
/translation="MLSLRQSIRFFKPATRTLCSSRYLLQQKPVVKTAQNLAEVNGPE
TLIGPGAKEGTVPTDLDQETGLARLELLGKLEGIDVFDTKPLDSSRKGTMKDPIIIES
YDDYRYVGCTGSPAGSHTIMWLKPTVNEVARCWECGSVYKLNPVGVPNDDHHH"
gene complement(151037..152776)
/gene="TPN1"
/locus_tag="YGL186C"
/db_xref="GeneID:852689"
mRNA complement(151037..152776)
/gene="TPN1"
/locus_tag="YGL186C"
/product="Tpn1p"
/transcript_id="NM_001181051.1"
/db_xref="GI:296144869"
/db_xref="GeneID:852689"
CDS complement(151037..152776)
/gene="TPN1"
/locus_tag="YGL186C"
/note="Plasma membrane pyridoxine (vitamin B6)
transporter; member of the purine-cytosine permease
subfamily within the major facilitator superfamily; proton
symporter with similarity to Fcy21p, Fcy2p, and Fcy22p"
/codon_start=1
/product="Tpn1p"
/protein_id="NP_011329.1"
/db_xref="GI:6321252"
/db_xref="SGD:S000003154"
/db_xref="GeneID:852689"
/translation="MNRDNMDTTKRKEDHTKHTTDVIEFYEEGTAASSLNIATEKANS
SPSILRRIINRAAWLSKKVDAMGVESTGIQRISPYERGTSKKQFLHVAGLWLSATGGL
SSMSSFLLGPLLFGLSFRESVASSLISVTIGCLIAAYCSIMGPQSGCRQMVTARYLFG
WWFVKLVALASIIGVMGWSVVNSVVGGEMLAAISNDKVPLWVGIVIVTVCSFLVAIFG
IKQVIKVETYLSVPVLTAFLLLYISSSDKYSFVNAYVSKGNLDSSTRKGNWMSFFSLC
YSITATWGSITADYYILFPEDTPYIQIFCLTFFGTFLPTCFVGILGLLLASVAMSYKP
WSVEYDSHGMGGLLWAGFQRWNGFGKFCVVVLVFSLVSNNIINTYSAAFSIQLSSVFC
AKIPRWFWSIVCTIICLVCALIGRNHFSTILGNFLPMIGYWISMYFILLFEENLVFRR
FFLHLYTKEFPTVTGEINGPELVGSSKEVEKDAVTNIHLLKRKHKVTKHRYNWDKWED
YEVLTHGYAATFAFIVGVAGVVVGMAQAYWIGPIAAKFGEYGGDVAMWLSMAFSGVVY
PPCRYLELRKFGR"
gene complement(153167..154306)
/locus_tag="YGL185C"
/db_xref="GeneID:852690"
mRNA complement(153167..154306)
/locus_tag="YGL185C"
/product="putative hydroxyacid dehydrogenase"
/transcript_id="NM_001181050.1"
/db_xref="GI:296144870"
/db_xref="GeneID:852690"
CDS complement(153167..154306)
/locus_tag="YGL185C"
/EC_number="1.-.-.-"
/note="Putative protein with sequence similarity to
hydroxyacid dehydrogenases; green fluorescent protein
(GFP)-fusion protein localizes to the cytoplasm"
/codon_start=1
/product="putative hydroxyacid dehydrogenase"
/protein_id="NP_011330.1"
/db_xref="GI:6321253"
/db_xref="SGD:S000003153"
/db_xref="GeneID:852690"
/translation="MCDSPATTGKPTILFIADPCETSATLNSKAFKEKFRILRYQLDT
KEAFLNFLERHEQDKICAIYAGFPAFKKIGGMTRSIIEHKSFPRKNLKCIVLCSRGYD
GWDLDTLRKHEIRLYNYQDDENEKLIDDLKLHQVGNDVADCALWHILEGFRKFSYYQK
LSRETGNTLTARAKAAEKSGFAFGHELGNMFAESPRGKKCLILGLGSIGKQVAYKLQY
GLGMEIHYCKRSEDCTMSQNESWKFHLLDETIYAKLYQFHAIVVTLPGTPQTEHLINR
KFLEHCNPGLILVNLGRGKILDLRAVSDALVTGRINHLGLDVFNKEPEIDEKIRSSDR
LTSITPHLGSATKDVFEQSCELALTRILRVVSGEAASDEHFSRVV"
gene complement(154615..156012)
/gene="STR3"
/locus_tag="YGL184C"
/db_xref="GeneID:852691"
mRNA complement(154615..156012)
/gene="STR3"
/locus_tag="YGL184C"
/product="cystathionine beta-lyase STR3"
/transcript_id="NM_001181049.3"
/db_xref="GI:398364308"
/db_xref="GeneID:852691"
CDS complement(154615..156012)
/gene="STR3"
/locus_tag="YGL184C"
/EC_number="4.4.1.8"
/note="Peroxisomal cystathionine beta-lyase, converts
cystathionine into homocysteine; may be redox regulated by
Gto1p"
/codon_start=1
/product="cystathionine beta-lyase STR3"
/protein_id="NP_011331.3"
/db_xref="GI:398364309"
/db_xref="SGD:S000003152"
/db_xref="GeneID:852691"
/translation="MPIKRLDTVVVNTGSQNDQHSASVPPVYLSTTFKVDLNNEDAQN
YDYSRSGNPTRSVLQHQIGKLYRVPQENVLAVSSGMTALDVILRGLVLLNGTDNHTPT
IIAGDDLYGGTQRLLNFFKQQSHAVSVHVDTSDFEKFKTVFQSLDKVDCVLLESPTNP
LCKVVDIPRILRFVKCISPDTTVVVDNTMMSGLNCNPLQLNPGCDVVYESATKYLNGH
HDLMGGVIISKTPEIASKLYFVINSTGAGLSPMDSWLLVRGLKTLGVRLYQQQRNAMI
LAHWLENSCGFKPTRTNKATKTRFVGLRSNPDFKLHKSFNNGPGAVLSFETGSFEHSK
RLVSSKKLSIWAVTVSFGCVNSLLSMPCKMSHASIDPELRKERDFPEDLVRLCCGIEN
IVDLKKDLLAAMVDADIIEVRENGKYLFNKLNKNLAVNTTIDDLHKPLSIYEEFYNQD
LIRKDSELNIKSSKL"
gene complement(156543..157285)
/gene="MND1"
/locus_tag="YGL183C"
/db_xref="GeneID:852692"
mRNA complement(join(156543..157199,157283..157285))
/gene="MND1"
/locus_tag="YGL183C"
/product="Mnd1p"
/transcript_id="NM_001181048.1"
/db_xref="GI:296144872"
/db_xref="GeneID:852692"
CDS complement(join(156543..157199,157283..157285))
/gene="MND1"
/locus_tag="YGL183C"
/note="Protein required for recombination and meiotic
nuclear division; forms a complex with Hop2p, which is
involved in chromosome pairing and repair of meiotic
double-strand breaks"
/codon_start=1
/product="Mnd1p"
/protein_id="NP_011332.2"
/db_xref="GI:27808704"
/db_xref="SGD:S000003151"
/db_xref="GeneID:852692"
/translation="MGPKRQTVSLQEKKNRILNFFQETYTFYNIKELEKSIPKKCGIS
PMIVKDLVQQMIDEDGVISVEKCGNINIYWCFKNQTLQKLYDSSELIKKKIQEVKCDI
ATYKQELDKTLATGRRKKFTVGQKSYNREALLEKRKKIQDEIKKKSNSLQKIESIRWD
AAKIQENKQQIRLKKVHLEKTTDNIEILIDYLYKKFFLKPEQIRKEFGIPEEFKEFTE
V"
gene 157906..159096
/gene="GTS1"
/locus_tag="YGL181W"
/gene_synonym="FHT1; LSR1"
/db_xref="GeneID:852694"
mRNA 157906..159096
/gene="GTS1"
/locus_tag="YGL181W"
/gene_synonym="FHT1; LSR1"
/product="Gts1p"
/transcript_id="NM_001181046.1"
/db_xref="GI:296144873"
/db_xref="GeneID:852694"
CDS 157906..159096
/gene="GTS1"
/locus_tag="YGL181W"
/gene_synonym="FHT1; LSR1"
/note="Protein involved in Arf3p regulation and in
transcription regulation; localizes to the nucleus and to
endocytic patches; contains an N-terminal Zn-finger and
ArfGAP homology domain, a C-terminal glutamine-rich
region, and a UBA (ubiquitin associated) domain; gts1
mutations affect budding, cell size, heat tolerance,
sporulation, life span, ultradian rhythms, endocytosis;
expression oscillates in a pattern similar to metabolic
oscillations"
/codon_start=1
/product="Gts1p"
/protein_id="NP_011334.1"
/db_xref="GI:6321257"
/db_xref="SGD:S000003149"
/db_xref="GeneID:852694"
/translation="MRFRSSSHSLKHVDRELKELINSSENANKCGECGNFYPTWCSVN
LGVFLCGRCASVHRKVFGSRDDDAFSNVKSLSMDRWTREDIDELVSLGGNKGNARFWN
PKNVPFPFDGDDDKAIVEHYIRDKYILGKFRYDEIKPEDFGSRMDDFDGESDRFDERN
RSRSRSRSHSFYKGGHNRSDYGGSRDSFQSSGSRYSRQLAELKDMGFGDTNKNLDALS
SAHGNINRAIDYLEKSSSSRNSVSAAATTSTPPLPRRRATTSGPQPAIFDGTNVITPD
FTSNSASFVQAKPAVFDGTLQQYYDPATGMIYVDQQQYAMAMQQQQQQQQQLAVAQAQ
AQAQAQAQAQVQAQAQAQAQAQAQAQQIQMQQLQMQQQQQAPLSFQQMSQGGNLPQGY
FYTQ"
gene 160065..162758
/gene="ATG1"
/locus_tag="YGL180W"
/gene_synonym="APG1; AUT3; CVT10"
/db_xref="GeneID:852695"
mRNA 160065..162758
/gene="ATG1"
/locus_tag="YGL180W"
/gene_synonym="APG1; AUT3; CVT10"
/product="Atg1p"
/transcript_id="NM_001181045.1"
/db_xref="GI:296144874"
/db_xref="GeneID:852695"
CDS 160065..162758
/gene="ATG1"
/locus_tag="YGL180W"
/gene_synonym="APG1; AUT3; CVT10"
/EC_number="2.7.11.1"
/note="Protein ser/thr kinase required for vesicle
formation in autophagy and the cytoplasm-to-vacuole
targeting (Cvt) pathway; structurally required for
phagophore assembly site formation; during autophagy forms
a complex with Atg13p and Atg17p"
/codon_start=1
/product="Atg1p"
/protein_id="NP_011335.1"
/db_xref="GI:6321258"
/db_xref="SGD:S000003148"
/db_xref="GeneID:852695"
/translation="MGDIKNKDHTTSVNHNLMASAGNYTAEKEIGKGSFATVYRGHLT
SDKSQHVAIKEVSRAKLKNKKLLENLEIEIAILKKIKHPHIVGLIDCERTSTDFYLIM
EYCALGDLTFLLKRRKELMENHPLLRTVFEKYPPPSENHNGLHRAFVLSYLQQLASAL
KFLRSKNLVHRDIKPQNLLLSTPLIGYHDSKSFHELGFVGIYNLPILKIADFGFARFL
PNTSLAETLCGSPLYMAPEILNYQKYNAKADLWSVGTVVFEMCCGTPPFRASNHLELF
KKIKRANDVITFPSYCNIEPELKELICSLLTFDPAQRIGFEEFFANKVVNEDLSSYEL
EDDLPELESKSKGIVESNMFVSEYLSKQPKSPNSNLAGHQSMADNPAELSDALKNSNI
LTAPAVKTDHTQAVDKKASNNKYHNSLVSDRSFEREYVVVEKKSVEVNSLADEVAQAG
FNPNPIKHPTSTQNQNVLLNEQFSPNNQQYFQNQGENPRLLRATSSSSGGSDGSRRPS
LVDRRLSISSLNPSNALSRALGIASTRLFGGANQQQQQQQITSSPPYSQTLLNSQLFH
ELTENIILRIDHLQHPETLKLDNTNIVSILESLAAKAFVVYSYAEVKFSQIVPLSTTL
KGMANFENRRSMDSNAIAEEQDSDDAEEEDETLKKYKEDCLSTKTFGKGRTLSATSQL
SATFNKLPRSEMILLCNEAIVLYMKALSILSKSMQVTSNWWYESQEKSCSLRVNVLVQ
WLREKFNECLEKADFLRLKINDLRFKHASEVAENQTLEEKGSSEEPVYLEKLLYDRAL
EISKMAAHMELKGENLYNCELAYATSLWMLETSLDDDDFTNAYGDYPFKTNIHLKSND
VEDKEKYHSVLDENDRIIIRKYIDSIANRLKILRQKMNHQN"
rep_origin 163177..163443
/note="ARS707;
Autonomously Replicating Sequence"
/db_xref="SGD:S000118453"
gene complement(163409..165091)
/gene="TOS3"
/locus_tag="YGL179C"
/db_xref="GeneID:852696"
mRNA complement(163409..165091)
/gene="TOS3"
/locus_tag="YGL179C"
/product="Tos3p"
/transcript_id="NM_001181044.3"
/db_xref="GI:398364314"
/db_xref="GeneID:852696"
CDS complement(163409..165091)
/gene="TOS3"
/locus_tag="YGL179C"
/EC_number="2.7.11.1"
/note="Protein kinase, related to and functionally
redundant with Elm1p and Sak1p for the phosphorylation and
activation of Snf1p; functionally orthologous to LKB1, a
mammalian kinase associated with Peutz-Jeghers
cancer-susceptibility syndrome"
/codon_start=1
/product="Tos3p"
/protein_id="NP_011336.3"
/db_xref="GI:398364315"
/db_xref="SGD:S000003147"
/db_xref="GeneID:852696"
/translation="MVLLKEPVQPLPRSSLLYNNASNSSSRIKETRKVKLLYNPLTKR
QILNNFEILATLGNGQYGKVKLARDLGTGALVAIKILNRFEKRSGYSLQLKVENPRVN
QEIEVMKRCHHENVVELYEILNDPESTKVYLVLEYCSRGPVKWCPENKMEIKAVGPSI
LTFQQSRKVVLDVVSGLEYLHSQGITHRDIKPSNLLISSNGTVKISDFGVAMSTATGS
TNIQSSHEQLLKSRALGTPAFFAPELCSTEKEYSCSSAIDIWSLGVTIYCLLFGKLPF
NANSGLELFDSIINKPLEFPSYEEMLNGATSGITMEEYTDAKDLLKKLLQKDPDKRIK
LADIKVHPFMCHYGKSDAASVLTNLETFHELKVSPPSSCKRVELVSLPVNSSFASLDS
VYMENFDHNNLRTGADRNSTYSPSIYDANTLSPSAYHNIGSRESSYSSFSSFTSSTAF
ASQISIQDAPAIGDQQCLIGESGSSLRVNSCEFPQYTTMSPVGEYPFESTEASLSSTL
TPVGNVPQRIKAHLVEGKSNSKDDLRIEADASLVFEASDAQRTRRRMSLYKL"
gene 167352..170571
/gene="MPT5"
/locus_tag="YGL178W"
/gene_synonym="HTR1; PUF5; UTH4"
/db_xref="GeneID:852697"
mRNA join(167352..167354,167995..170571)
/gene="MPT5"
/locus_tag="YGL178W"
/gene_synonym="HTR1; PUF5; UTH4"
/product="Mpt5p"
/transcript_id="NM_001181043.1"
/db_xref="GI:296144876"
/db_xref="GeneID:852697"
CDS join(167352..167354,167995..170571)
/gene="MPT5"
/locus_tag="YGL178W"
/gene_synonym="HTR1; PUF5; UTH4"
/note="mRNA-binding protein of the PUF family; binds to
the 3' UTR of specific mRNAs, including those involved in
mating type switching, cell wall integrity, chronological
lifespan, chromatin modification, and spindle pole body
architecture; recruits the CCR4-NOT deadenylase complex to
mRNAs along with Dhh1p and Dcp1p to promote deadenylation,
decapping, and decay; also interacts with the Caf20p
translational initiation repressor, affecting its mRNA
target specificity"
/codon_start=1
/product="Mpt5p"
/protein_id="NP_011337.1"
/db_xref="GI:6321260"
/db_xref="SGD:S000003146"
/db_xref="GeneID:852697"
/translation="MINNEPFPSADSASILTTSTSNNSLMSYNHQPQLSINSVQSLLE
PVTPPPLGQMNNKRNHQKAHSLDLSGFNQFISSTQSPLALMNNTSTSNSANSFSPNPN
AASNSTGLSASMANPPAILPLINEFDLEMDGPRRKSSHDFTVVAPSNSGVNTSSLIME
TPSSSVTPAASLRNFSNSNNAASKCGVDNSSFGLSSSTSSSMVEISALPLRDLDYIKL
ATDQFGCRFLQKKLETPSESNMVRDLMYEQIKPFFLDLILDPFGNYLVQKLCDYLTAE
QKTLLIQTIYPNVFQISINQYGTRSLQKIIDTVDNEVQIDLIIKGFSQEFTSIEQVVT
LINDLNGNHVIQKCIFKFSPSKFGFIIDAIVEQNNIITISTHKHGCCVLQKLLSVCTL
QQIFKISVKIVQFLPGLINDQFGNYIIQFLLDIKELDFYLLAELFNRLSNELCQLSCL
KFSSNVVEKFIKKLFRIITGFIVNNNGGASQRTAVASDDVINASMNILLTTIDIFTVN
LNVLIRDNFGNYALQTLLDVKNYSPLLAYNKNSNAIGQNSSSTLNYGNFCNDFSLKIG
NLIVLTKELLPSIKTTSYAKKIKLKVKAYAEATGIPFTDISPQVTAMSHNNLQTINNE
NKNPHNKNSHNHNHNHNHNHAHNNNNNNNQKSHTRHFSLPANAYHRRSNSSVTNNFSN
QYAQDQKIHSPQQIMNFNQNAYPSMGAPSFNSQTNPPLVSHNSLQNFDNRQFANLMAH
PNSAAPIHSFSSSNITNVNPNVSRGFKQPGFMMNETDKINANHFSPYSNANSQNFNES
FVPRMQYQTEGANWDSSLSMKSQHIGQGPYNQVNMSRNASISNMPAMNTARTSDELQF
TLP"
gene complement(171415..173079)
/locus_tag="YGL176C"
/db_xref="GeneID:852699"
mRNA complement(171415..173079)
/locus_tag="YGL176C"
/product="hypothetical protein"
/transcript_id="NM_001181041.1"
/db_xref="GI:296144877"
/db_xref="GeneID:852699"
CDS complement(171415..173079)
/locus_tag="YGL176C"
/note="hypothetical protein; deletion mutant is viable and
has no detectable phenotype"
/codon_start=1
/product="hypothetical protein"
/protein_id="NP_011339.1"
/db_xref="GI:6321262"
/db_xref="SGD:S000003144"
/db_xref="GeneID:852699"
/translation="MTPNLPGFYYDRERRRYFRISENQSISTTGTTNQYRKDNIKRQC
VEENYDKKFSMIKKKRQQTLQKYKLSLLNPLERAFRPLSYEKYMIGLNMQYASHSLTE
GHHSHSSANVKSLNFPHRIQIGVLANCILLVTQEGCFHSKLVFATNKGYVAGFSSLDN
FSEENFFTGFSMAELNPMLKYKSEPTDVFKTMKLERTVAIKEGPSHYFYHNVNTRSNV
HTFAIFLQDFSSLKLLKIRQVKLKENCQVHDSLVVGDTLIITVNYRCHFYDLIPETFP
NPYIFSPAKSSRKHKSRSDITSLSFCLQEDALSPLKKTNTGVFYLGYRNGDSMAIVFT
NITNMTLQYSKTNGMTSESRNQPIRNSLKSVVSIKALNNKGLILISGMADKENVQQLV
IADTFLEDILTEIPVVSFKTKFLNVTKDTEILEISDDGRYFIYGSTSARDGKGDFEVF
CTTLSGNLDYEKSEGGNITLYPIGGMKNYCRLENFQFESIHLHSAFIPPRYVNPFDAV
EPLGEESSTSPYDIPEEALSQKICILIRREDDPYNGANIFITSALT"
gene complement(173285..174322)
/gene="SAE2"
/locus_tag="YGL175C"
/gene_synonym="COM1"
/db_xref="GeneID:852700"
mRNA complement(173285..174322)
/gene="SAE2"
/locus_tag="YGL175C"
/gene_synonym="COM1"
/product="Sae2p"
/transcript_id="NM_001181040.1"
/db_xref="GI:296144878"
/db_xref="GeneID:852700"
CDS complement(173285..174322)
/gene="SAE2"
/locus_tag="YGL175C"
/gene_synonym="COM1"
/note="Endonuclease that processes hairpin DNA structures
with the MRX complex; involved in meiotic and mitotic
double-strand break repair; phosphorylated in response to
DNA damage and required for normal resistance to
DNA-damaging agents"
/codon_start=1
/product="Sae2p"
/protein_id="NP_011340.1"
/db_xref="GI:6321263"
/db_xref="SGD:S000003143"
/db_xref="GeneID:852700"
/translation="MVTGEENVYLKSSLSILKELSLDELLNVQYDVTTLIAKRVQALQ
NRNKCVLEEPNSKLAEILCHEKNAPQQSSQTSAGPGEQDSEDFILTQFDEDIKKESAE
VHYRNENKHTVQLPLVTMPPNRHKRKISEFSSPLNGLNNLSDLEDCSDTVIHEKDNDK
ENKTRKLLGIELENPESTSPNLYKNVKDNFLFDFNTNPLTKRAWILEDFRPNEDIAPV
KRGRRKLERFYAQVGKPEDSKHRSLSVVIESQNSDYEFAFDNLRNRSKSPPGFGRLDF
PSTQEGNEDKKKSQEIIRRKTKYRFLMASNNKIPPYEREYVFKREQLNQIVDDGCFFW
SDKLLQIYARC"
gene 174545..175345
/gene="BUD13"
/locus_tag="YGL174W"
/gene_synonym="CWC26"
/db_xref="GeneID:852701"
mRNA 174545..175345
/gene="BUD13"
/locus_tag="YGL174W"
/gene_synonym="CWC26"
/product="Bud13p"
/transcript_id="NM_001181039.3"
/db_xref="GI:398364328"
/db_xref="GeneID:852701"
CDS 174545..175345
/gene="BUD13"
/locus_tag="YGL174W"
/gene_synonym="CWC26"
/note="Subunit of the RES complex, which is required for
nuclear pre-mRNA retention and splicing; involved in
bud-site selection; diploid mutants display a unipolar
budding pattern instead of the wild-type bipolar pattern"
/codon_start=1
/product="Bud13p"
/protein_id="NP_011341.3"
/db_xref="GI:398364329"
/db_xref="SGD:S000003142"
/db_xref="GeneID:852701"
/translation="MALHQYLSETYGPTKPKNKTKKKKKESKSDANSDKTSLIVKERL
STLQQEQEKSGVASFSKFDKQKSKNIWKNLETNELSHAITHPSASSITGNESKNDLKE
IRAQEPLVTVADKSKTRKTIYRDAQGHKIQEDSKIDDSSFSRSKYEDEKAAEREQYLK
NLNMGDVQKLGINVDAHDKKKNQTASSLTIEDPAITFTHDKERTVKTSLLGRKLYDKP
APENRFAIMPGSRWDGVHRSNGFEEKWFAKQNEINEKKVQSYTLQEDY"
gene complement(175527..180113)
/gene="XRN1"
/locus_tag="YGL173C"
/gene_synonym="DST2; KEM1; RAR5; SEP1; SKI1"
/db_xref="GeneID:852702"
mRNA complement(175527..180113)
/gene="XRN1"
/locus_tag="YGL173C"
/gene_synonym="DST2; KEM1; RAR5; SEP1; SKI1"
/product="Xrn1p"
/transcript_id="NM_001181038.1"
/db_xref="GI:296144880"
/db_xref="GeneID:852702"
CDS complement(175527..180113)
/gene="XRN1"
/locus_tag="YGL173C"
/gene_synonym="DST2; KEM1; RAR5; SEP1; SKI1"
/EC_number="3.1.11.-"
/note="Evolutionarily-conserved 5'-3' exonuclease
component of cytoplasmic processing (P) bodies involved in
mRNA decay; plays a role in microtubule-mediated
processes, filamentous growth, ribosomal RNA maturation,
and telomere maintenance; activated by the scavenger
decapping enzyme Dcs1p"
/codon_start=1
/product="Xrn1p"
/protein_id="NP_011342.1"
/db_xref="GI:6321265"
/db_xref="SGD:S000003141"
/db_xref="GeneID:852702"
/translation="MGIPKFFRYISERWPMILQLIEGTQIPEFDNLYLDMNSILHNCT
HGNDDDVTKRLTEEEVFAKICTYIDHLFQTIKPKKIFYMAIDGVAPRAKMNQQRARRF
RTAMDAEKALKKAIENGDEIPKGEPFDSNSITPGTEFMAKLTKNLQYFIHDKISNDSK
WREVQIIFSGHEVPGEGEHKIMNFIRHLKSQKDFNQNTRHCIYGLDADLIMLGLSTHG
PHFALLREEVTFGRRNSEKKSLEHQNFYLLHLSLLREYMELEFKEIADEMQFEYNFER
ILDDFILVMFVIGNDFLPNLPDLHLNKGAFPVLLQTFKEALLHTDGYINEHGKINLKR
LGVWLNYLSQFELLNFEKDDIDVEWFNKQLENISLEGERKRQRVGKKLLVKQQKKLIG
SIKPWLMEQLQEKLSPDLPDEEIPTLELPKDLDMKDHLEFLKEFAFDLGLFITHSKSK
GSYSLKMDLDSINPDETEEEFQNRVNSIRKTIKKYQNAIIVEDKEELETEKTIYNERF
ERWKHEYYHDKLKFTTDSEEKVRDLAKDYVEGLQWVLYYYYRGCPSWSWYYPHHYAPR
ISDLAKGLDQDIEFDLSKPFTPFQQLMAVLPERSKNLIPPAFRPLMYDEQSPIHDFYP
AEVQLDKNGKTADWEAVVLISFVDEKRLIEAMQPYLRKLSPEEKTRNQFGKDLIYSFN
PQVDNLYKSPLGGIFSDIEHNHCVEKEYITIPLDSSEIRYGLLPNAKLGAEMLAGFPT
LLSLPFTSSLEYNETMVFQQPSKQQSMVLQITDIYKTNNVTLEDFSKRHLNKVIYTRW
PYLRESKLVSLTDGKTIYEYQESNDKKKFGFITKPAETQDKKLFNSLKNSMLRMYAKQ
KAVKIGPMEAIATVFPVTGLVRDSDGGYIKTFSPTPDYYPLQLVVESVVNEDERYKER
GPIPIEEEFPLNSKVIFLGDYAYGGETTIDGYSSDRRLKITVEKKFLDSEPTIGKERL
QMDHQAVKYYPSYIVSKNMHLHPLFLSKITSKFMITDATGKHINVGIPVKFEARHQKV
LGYARRNPRGWEYSNLTLNLLKEYRQTFPDFFFRLSKVGNDIPVLEDLFPDTSTKDAM
NLLDGIKQWLKYVSSKFIAVSLESDSLTKTSIAAVEDHIMKYAANIEGHERKQLAKVP
REAVLNPRSSFALLRSQKFDLGDRVVYIQDSGKVPIFSKGTVVGYTTLSSSLSIQVLF
DHEIVAGNNFGGRLRTNRGLGLDASFLLNITNRQFIYHSKASKKALEKKKQSNNRNNN
TKTAHKTPSKQQSEEKLRKERAHDLLNFIKKDTNEKNSESVDNKSMGSQKDSKPAKKV
LLKRPAQKSSENVQVDLANFEKAPLDNPTVAGSIFNAVANQYSDGIGSNLNIPTPPHP
MNVVGGPIPGANDVADVGLPYNIPPGFMTHPNGLHPLHPHQMPYPNMNGMSIPPPAPH
GFGQPISFPPPPPMTNVSDQGSRIVVNEKESQDLKKFINGKQHSNGSTIGGETKNSRK
GEIKPSSGTNSTECQSPKSQSNAADRDNKKDEST"
gene 180700..182118
/gene="NUP49"
/locus_tag="YGL172W"
/gene_synonym="NSP49"
/db_xref="GeneID:852703"
mRNA 180700..182118
/gene="NUP49"
/locus_tag="YGL172W"
/gene_synonym="NSP49"
/product="Nup49p"
/transcript_id="NM_001181037.1"
/db_xref="GI:296144881"
/db_xref="GeneID:852703"
CDS 180700..182118
/gene="NUP49"
/locus_tag="YGL172W"
/gene_synonym="NSP49"
/note="FG-nucleoporin component of central core of the
nuclear pore complex (NPC); contributes directly to
nucleocytoplasmic transport and maintenance of the NPC
permeability barrier; found in stable complex with Nic96p
and two other FG-nucleoproteins (Nsp1p and Nup57p)"
/codon_start=1
/product="Nup49p"
/protein_id="NP_011343.1"
/db_xref="GI:6321266"
/db_xref="SGD:S000003140"
/db_xref="GeneID:852703"
/translation="MFGLNKASSTPAGGLFGQASGASTGNANTGFSFGGTQTGQNTGP
STGGLFGAKPAGSTGGLGASFGQQQQQSQTNAFGGSATTGGGLFGNKPNNTANTGGGL
FGANSNSNSGSLFGSNNAQTSRGLFGNNNTNNINNSSSGMNNASAGLFGSKPAGGTSL
FGNTSTSSAPAQNQGMFGAKPAGTSLFGNNAGNTTTGGGLFGSKPTGATSLFGSSNNN
NNNNNSNNIMSASGGLFGNQQQQLQQQPQMQCALQNLSQLPITPMTRISELPPQIRQE
IEQLDQYIQKQVQISHHLKADTIDHDELIDSIPRDVAYLLKSESATSQYLKQDLKKIS
SFKSLIDEDLLDTQTFSVLLQQLLTPGSKISSNDLDKFFQKKIHLYEKKLEDYCRILS
DIETAVNGIDTDLFGAPNNPNSTAITADLGSSEAENLLQLKTGLAAIVSTVIEEFTLF
MDIAERIAVLHQKTKTLASLSI"
gene 182390..184084
/gene="ROK1"
/locus_tag="YGL171W"
/db_xref="GeneID:852704"
mRNA 182390..184084
/gene="ROK1"
/locus_tag="YGL171W"
/product="RNA-dependent ATPase ROK1"
/transcript_id="NM_001181036.1"
/db_xref="GI:296144882"
/db_xref="GeneID:852704"
CDS 182390..184084
/gene="ROK1"
/locus_tag="YGL171W"
/EC_number="3.6.1.-"
/note="RNA-dependent ATPase; involved in pre-rRNA
processing at sites A0, A1, and A2, and in control of cell
cycle progression; contains two upstream open reading
frames (uORFs) in 5' untranslated region which regulate
translation"
/codon_start=1
/product="RNA-dependent ATPase ROK1"
/protein_id="NP_011344.1"
/db_xref="GI:6321267"
/db_xref="SGD:S000003139"
/db_xref="GeneID:852704"
/translation="MDIFRVLTRGASVKKESGPKAKAADYSVINGNDENHKEDNNESQ
IVKELDFFRNKRIISKVEDDREKTTENDSPNKEEKSGNDDGLIKPVITNTVEASALRK
SYKGNVSGIDIPLPIGSFEDLISRFSFDKRLLNNLIENGFTEPTPIQCECIPVALNNR
DVLACGPTGSGKTLAFLIPLVQQIIDDKQTAGLKGLIISPTKELANQIFIECFKLSYK
IFLEKKRPLQVALLSKSLGAKLKNKVVSDKKYDIIISTPLRLIDVVKNEALDLSKVKH
LIFDEADKLFDKTFVEQSDDILSACREPSLRKAMFSATIPSNVEEIAQSIMMDPVRVI
IGHKEAANTNIEQKLIFCGNEEGKLIAIRQLVQEGEFKPPIIIFLESITRAKALYHEL
MYDRINVDVIHAERTALQRDRIIERFKTGELWCLICTDVLARGIDFKGVNLVINYDVP
GSSQAYVHRIGRTGRGGRSGKAITFYTKQDSVAIKPIINVMKQSGCEVSEWMDKMAKM
TRKEKESIKNGKAHKERKQITTVPKMDKAKRRRQQEMIAASKRRKNEELSKKHFSK"
gene complement(184153..185394)
/gene="SPO74"
/locus_tag="YGL170C"
/db_xref="GeneID:852705"
mRNA complement(184153..185394)
/gene="SPO74"
/locus_tag="YGL170C"
/product="Spo74p"
/transcript_id="NM_001181035.3"
/db_xref="GI:398364336"
/db_xref="GeneID:852705"
CDS complement(184153..185394)
/gene="SPO74"
/locus_tag="YGL170C"
/note="Component of the meiotic outer plaque of the
spindle pole body, involved in modifying the meiotic outer
plaque that is required prior to prospore membrane
formation"
/codon_start=1
/product="Spo74p"
/protein_id="NP_011345.3"
/db_xref="GI:398364337"
/db_xref="SGD:S000003138"
/db_xref="GeneID:852705"
/translation="MGAGTLLNGLEKENFPNNIHSDLPAYPNMDSQEDGNTSKESKRN
SPVKQKSQKDEEKSSKMGTASNIFHENKDIHERSEHTDDFNDGLKLAPDSSPSLKECQ
FKNWESFWCNTEGYKTKHMQPFHFTSGLEEIKEPVMELNISTSPYKGQRPNSAPTEYS
AATTAFTKTQLEVSFLKTNLLTYIKKEIDICLSSVPFFDDAVQMQKKFLEYRDIDLDE
EYELKILGELLNDLNFFHMQENSLLNRELAVRRFSNQPESQNLPSIRDFRNPLLPIDN
RPSPPLGLKRNGKSFEETYDFTSNTSNFWGEKAELQNSITGGTPYFFHPNNIHQTKPF
MSFENQNELLFQRKNSDYKQHFNSGRNIHNGVESKSYRGVGLNDSYQKGYAAMTKSFG
NIDLNRMPRRSNEEMYSWSRN"
gene complement(185714..185786)
/locus_tag="tK(CUU)G2"
/db_xref="GeneID:852706"
tRNA complement(185714..185786)
/locus_tag="tK(CUU)G2"
/product="tRNA-Lys"
/note="Lysine tRNA (tRNA-Lys), predicted by tRNAscan-SE
analysis; a small portion is imported into mitochondria
via interaction with mt lysyl-tRNA synthetase Msk1p and is
necessary to decode AAG codons at high temperature, when
base modification of mt-encoded tRNA-Lys is reduced"
/db_xref="SGD:S000006622"
/db_xref="GeneID:852706"
gene 186059..187339
/gene="SUA5"
/locus_tag="YGL169W"
/db_xref="GeneID:852707"
mRNA 186059..187339
/gene="SUA5"
/locus_tag="YGL169W"
/product="Sua5p"
/transcript_id="NM_001181034.1"
/db_xref="GI:296144884"
/db_xref="GeneID:852707"
CDS 186059..187339
/gene="SUA5"
/locus_tag="YGL169W"
/note="Single-stranded telomeric DNA-binding protein,
required for normal telomere length; null mutant lacks
N6-threonylcarbamoyl adenosine (t6A) modification in the
anticodon loop of ANN-decoding tRNA; member of conserved
YrdC/Sua5 family"
/codon_start=1
/product="Sua5p"
/protein_id="NP_011346.1"
/db_xref="GI:6321269"
/db_xref="SGD:S000003137"
/db_xref="GeneID:852707"
/translation="MYLGRHFLAMTSKALFDTKILKVNPLSIIFSPDAHIDGSLPTIT
DPETEAALVEAARIIRDTDETVAFPTETVYGLGGSALNDNSVLSIYRAKNRPSDNPLI
THVSSIDQLNRKVFNQPHLSGTSLFDNIPSIYRPLISSLWPGPLTILLPVPSSEHSAL
SKLTTADQPTFAVRIPANPVARALIALSDTPIAAPSANASTRPSPTLASHVYHDLKDK
IPIILDGGACKVGVESTVVDGLCNPPTLLRPGGFTYEEIVKLGGEAWSLCKVENKKTV
EKGEKVRTPGMKYRHYSPSAKVVLLVPHCEGDGILKGVDRMERLKRLIETELKANSNI
KKIAILTSLKLRDSDLQSKIFNEPDFSSKTFIIERLGQSGEEIQTNLFAALRKVDEND
KVDLIFVEGINEEGEGLAVMNRLRKAAANNCIQF"
gene 187464..187796
/gene="HUR1"
/locus_tag="YGL168W"
/db_xref="GeneID:852708"
mRNA 187464..187796
/gene="HUR1"
/locus_tag="YGL168W"
/product="Hur1p"
/transcript_id="NM_001181033.1"
/db_xref="GI:296144885"
/db_xref="GeneID:852708"
CDS 187464..187796
/gene="HUR1"
/locus_tag="YGL168W"
/note="hypothetical protein; reported null mutant
phenotype of hydroxyurea sensitivity may be due to effects
on overlapping PMR1 gene"
/codon_start=1
/product="Hur1p"
/protein_id="NP_011347.1"
/db_xref="GI:6321270"
/db_xref="SGD:S000003136"
/db_xref="GeneID:852708"
/translation="MFILVSVVNICTYIHLHMFPLISTFTSIGLGVLMKDKGKEGKTI
KAQNVTYQTFEKYVESSSFFFLVHNFLNSSTMKTLLLMSNNNSISEIPSFSVLKILWK
NGIYIAHI"
rep_origin 187464..187796
/gene="HUR1"
/locus_tag="YGL168W"
/note="ARS709;
Replication origin; identified in multiple array studies,
confirmed by plasmid-based recombinational ARS assay"
/db_xref="SGD:S000130163"
gene complement(187616..190468)
/gene="PMR1"
/locus_tag="YGL167C"
/gene_synonym="BSD1; LDB1; SSC1"
/db_xref="GeneID:852709"
mRNA complement(187616..190468)
/gene="PMR1"
/locus_tag="YGL167C"
/gene_synonym="BSD1; LDB1; SSC1"
/product="Ca(2+)/Mn(2+)-transporting P-type ATPase PMR1"
/transcript_id="NM_001181032.1"
/db_xref="GI:296144886"
/db_xref="GeneID:852709"
CDS complement(187616..190468)
/gene="PMR1"
/locus_tag="YGL167C"
/gene_synonym="BSD1; LDB1; SSC1"
/EC_number="3.6.3.8"
/note="High affinity Ca2+/Mn2+ P-type ATPase required for
Ca2+ and Mn2+ transport into Golgi; involved in Ca2+
dependent protein sorting and processing; mutations in
human homolog ATP2C1 cause acantholytic skin condition
Hailey-Hailey disease"
/codon_start=1
/product="Ca(2+)/Mn(2+)-transporting P-type ATPase PMR1"
/protein_id="NP_011348.1"
/db_xref="GI:6321271"
/db_xref="SGD:S000003135"
/db_xref="GeneID:852709"
/translation="MSDNPFNASLLDEDSNREREILDATAEALSKPSPSLEYCTLSVD
EALEKLDTDKNGGLRSSNEANNRRSLYGPNEITVEDDESLFKKFLSNFIEDRMILLLI
GSAVVSLFMGNIDDAVSITLAIFIVVTVGFVQEYRSEKSLEALNKLVPAECHLMRCGQ
ESHVLASTLVPGDLVHFRIGDRIPADIRIIEAIDLSIDESNLTGENEPVHKTSQTIEK
SSFNDQPNSIVPISERSCIAYMGTLVKEGHGKGIVVGTGTNTSFGAVFEMMNNIEKPK
TPLQLTMDKLGKDLSLVSFIVIGMICLVGIIQGRSWLEMFQISVSLAVAAIPEGLPII
VTVTLALGVLRMAKRKAIVRRLPSVETLGSVNVICSDKTGTLTSNHMTVSKLWCLDSM
SNKLNVLSLDKNKKTKNSNGNLKNYLTEDVRETLTIGNLCNNASFSQEHAIFLGNPTD
VALLEQLANFEMPDIRNTVQKVQELPFNSKRKLMATKILNPVDNKCTVYVKGAFERIL
EYSTSYLKSKGKKTEKLTEAQKATINECANSMASEGLRVFGFAKLTLSDSSTPLTEDL
IKDLTFTGLIGMNDPPRPNVKFAIEQLLQGGVHIIMITGDSENTAVNIAKQIGIPVID
PKLSVLSGDKLDEMSDDQLANVIDHVNIFARATPEHKLNIVRALRKRGDVVAMTGDGV
NDAPALKLSDIGVSMGRIGTDVAKEASDMVLTDDDFSTILTAIEEGKGIFNNIQNFLT
FQLSTSVAALSLVALSTAFKLPNPLNAMQILWINILMDGPPAQSLGVEPVDHEVMKKP
PRKRTDKILTHDVMKRLLTTAACIIVGTVYIFVKEMAEDGKVTARDTTMTFTCFVFFD
MFNALACRHNTKSIFEIGFFTNKMFNYAVGLSLLGQMCAIYIPFFQSIFKTEKLGISD
ILLLLLISSSVFIVDELRKLWTRKKNEEDSTYFSNV"
gene 191129..191806
/gene="CUP2"
/locus_tag="YGL166W"
/gene_synonym="ACE1"
/db_xref="GeneID:852710"
mRNA 191129..191806
/gene="CUP2"
/locus_tag="YGL166W"
/gene_synonym="ACE1"
/product="Cup2p"
/transcript_id="NM_001181031.3"
/db_xref="GI:398364350"
/db_xref="GeneID:852710"
CDS 191129..191806
/gene="CUP2"
/locus_tag="YGL166W"
/gene_synonym="ACE1"
/note="Copper-binding transcription factor; activates
transcription of the metallothionein genes CUP1-1 and
CUP1-2 in response to elevated copper concentrations; CUP2
has a paralog, HAA1, that arose from the whole genome
duplication"
/codon_start=1
/product="Cup2p"
/protein_id="NP_011349.3"
/db_xref="GI:398364351"
/db_xref="SGD:S000003134"
/db_xref="GeneID:852710"
/translation="MVVINGVKYACETCIRGHRAAQCTHTDGPLQMIRRKGRPSTTCG
HCKELRRTKNFNPSGGCMCASARRPAVGSKEDETRCRCDEGEPCKCHTKRKSSRKSKG
GSCHRRANDEAAHVNGLGIADLDVLLGLNGRSSDVDMTTTLPSLKPPLQNGEIKADSI
DNLDLASLDPLEQSPSISMEPVSINETGSAYTTTNTALNDIDIPFSINELNELYKQVS
SHNSHSQ"
gene complement(191978..193300)
/gene="YRB30"
/locus_tag="YGL164C"
/db_xref="GeneID:852712"
mRNA complement(191978..193300)
/gene="YRB30"
/locus_tag="YGL164C"
/product="Yrb30p"
/transcript_id="NM_001181029.1"
/db_xref="GI:296144888"
/db_xref="GeneID:852712"
CDS complement(191978..193300)
/gene="YRB30"
/locus_tag="YGL164C"
/note="RanGTP-binding protein, inhibits RanGAP1
(Rna1p)-mediated GTP hydrolysis of RanGTP (Gsp1p); shares
similarity to proteins in other fungi but not in higher
eukaryotes"
/codon_start=1
/product="Yrb30p"
/protein_id="NP_011351.1"
/db_xref="GI:6321274"
/db_xref="SGD:S000003132"
/db_xref="GeneID:852712"
/translation="MDEILAKAGSQAVTFAIKSGISIASTYALKTITNFVVQIPKDDA
RRIDQLKFKLESRMAIVSSAIDLIKLVAARGNTNLQITLRLTKDLKEEIDRFDEKINE
MTQKVEGSRSAKTQNEAIKAVENYIKDLLLRIEEITPFINLSLTTSGANLNSALPYQL
SPGLLLKASDFVSENNRKYEKAMKSNEKGTGDKEILKVQVGPTFEVTLFSIFYNLTSE
NNGQSGIVWKEDMKRAKARIYRLNSTGRKYDYFMKIEQDFNDGRYHEDDDKEDTPQEL
AIDLNHIKKLFFSVSGKLLRLEEQDSPVLVLKIDRSDDKENESSEGDKGLLDDITWYA
VSGYEAIEEDEEEDEEEDEEEGKDGEERKEEEEEENKLEDKDSSITLLEYIIRLTSLQ
SNDQKSILEVSDERLSIYLNDENTNSRKDRISNSTIEETEKKLKNLKL"
gene complement(193707..196403)
/gene="RAD54"
/locus_tag="YGL163C"
/gene_synonym="XRS1"
/db_xref="GeneID:852713"
mRNA complement(193707..196403)
/gene="RAD54"
/locus_tag="YGL163C"
/gene_synonym="XRS1"
/product="DNA-dependent ATPase RAD54"
/transcript_id="NM_001181028.1"
/db_xref="GI:296144889"
/db_xref="GeneID:852713"
CDS complement(193707..196403)
/gene="RAD54"
/locus_tag="YGL163C"
/gene_synonym="XRS1"
/EC_number="3.6.1.-"
/note="DNA-dependent ATPase that stimulates strand
exchange; modifies the topology of double-stranded DNA;
involved in the recombinational repair of double-strand
breaks in DNA during vegetative growth and meiosis; member
of the SWI/SNF family; forms nuclear foci upon DNA
replication stress"
/codon_start=1
/product="DNA-dependent ATPase RAD54"
/protein_id="NP_011352.1"
/db_xref="GI:6321275"
/db_xref="SGD:S000003131"
/db_xref="GeneID:852713"
/translation="MARRRLPDRPPNGIGAGERPRLVPRPINVQDSVNRLTKPFRVPY
KNTHIPPAAGRIATGSDNIVGGRSLRKRSATVCYSGLDINADEAEYNSQDISFSQLTK
RRKDALSAQRLAKDPTRLSHIQYTLRRSFTVPIKGYVQRHSLPLTLGMKKKITPEPRP
LHDPTDEFAIVLYDPSVDGEMIVHDTSMDNKEEESKKMIKSTQEKDNINKEKNSQEER
PTQRIGRHPALMTNGVRNKPLRELLGDSENSAENKKKFASVPVVIDPKLAKILRPHQV
EGVRFLYRCVTGLVMKDYLEAEAFNTSSEDPLKSDEKALTESQKTEQNNRGAYGCIMA
DEMGLGKTLQCIALMWTLLRQGPQGKRLIDKCIIVCPSSLVNNWANELIKWLGPNTLT
PLAVDGKKSSMGGGNTTVSQAIHAWAQAQGRNIVKPVLIISYETLRRNVDQLKNCNVG
LMLADEGHRLKNGDSLTFTALDSISCPRRVILSGTPIQNDLSEYFALLSFSNPGLLGS
RAEFRKNFENPILRGRDADATDKEITKGEAQLQKLSTIVSKFIIRRTNDILAKYLPCK
YEHVIFVNLKPLQNELYNKLIKSREVKKVVKGVGGSQPLRAIGILKKLCNHPNLLNFE
DEFDDEDDLELPDDYNMPGSKARDVQTKYSAKFSILERFLHKIKTESDDKIVLISNYT
QTLDLIEKMCRYKHYSAVRLDGTMSINKRQKLVDRFNDPEGQEFIFLLSSKAGGCGIN
LIGANRLILMDPDWNPAADQQALARVWRDGQKKDCFIYRFISTGTIEEKIFQRQSMKM
SLSSCVVDAKEDVERLFSSDNLRQLFQKNENTICETHETYHCKRCNAQGKQLKRAPAM
LYGDATTWNHLNHDALEKTNDHLLKNEHHYNDISFAFQYISH"
gene 198138..199037
/gene="SUT1"
/locus_tag="YGL162W"
/db_xref="GeneID:852714"
mRNA 198138..199037
/gene="SUT1"
/locus_tag="YGL162W"
/product="Sut1p"
/transcript_id="NM_001181027.1"
/db_xref="GI:296144890"
/db_xref="GeneID:852714"
CDS 198138..199037
/gene="SUT1"
/locus_tag="YGL162W"
/note="Transcription factor of the Zn2Cys6 family involved
in sterol uptake; involved in induction of hypoxic gene
expression; relocalizes from nucleus to cytoplasm upon DNA
replication stress"
/codon_start=1
/product="Sut1p"
/protein_id="NP_011353.1"
/db_xref="GI:6321276"
/db_xref="SGD:S000003130"
/db_xref="GeneID:852714"
/translation="MSTSITVRNRDRSLPPLLLPNVSLLEKDIRRKGTQNVGITDPEL
LSTTWTRKRAFPTDELLGGYKRLKPAAADSNECAIGIATVTPPPTLPVSAIVPPPQNY
TPPLFEYHPHALASMVNEDANASCTQMSIISRSTSNSTTSSATSTSSISKRQRSGPSC
DKCRLKKIKCNAKIEILLQDDTIMPMISNKLRYVLTPDDIRLYRGTLLRNIAIPDDVI
EGTGSRKLIKHIDKLVLLTPCLPCIKKKHSSSSTNFPKNDKCTFSKGFTRADINISSK
ISLKFKDKTIYDITYDDYKSIDF"
gene complement(199210..200142)
/gene="YIP5"
/locus_tag="YGL161C"
/db_xref="GeneID:852715"
mRNA complement(199210..200142)
/gene="YIP5"
/locus_tag="YGL161C"
/product="Yip5p"
/transcript_id="NM_001181026.3"
/db_xref="GI:398364362"
/db_xref="GeneID:852715"
CDS complement(199210..200142)
/gene="YIP5"
/locus_tag="YGL161C"
/note="Protein that interacts with Rab GTPases, localized
to late Golgi vesicles; computational analysis of
large-scale protein-protein interaction data suggests a
possible role in vesicle-mediated transport"
/codon_start=1
/product="Yip5p"
/protein_id="NP_011354.3"
/db_xref="GI:398364363"
/db_xref="SGD:S000003129"
/db_xref="GeneID:852715"
/translation="MPSNNSSFLDIDDDLEGVDDFGNEPNPFDDATVPDSPNMNNSTA
GKGSEFYNTTGSKAESAPLQGQMDPPAYDQVIGQNDNDGLGRNGLRPGLINYYSKYFQ
IDLTQFKKRLSAVLTFRNDHNSESNEDNTDLYGAVWITATVVMINFTMSRGLNFIISD
VIEGVKTGEDIDRASQFKKLLHSIWLFYGYTFGVPFITMQVLNRDEHSERNRSFKSVP
ELISVYGYANLIWIPVCVILNILDMSKRLRTVQAIQWAIVALGWAQSSYFLNSQISSN
NNTETQSNGKFSLSIIVVVALHTLFCLLFRFIIF"
gene 200561..202273
/gene="AIM14"
/locus_tag="YGL160W"
/gene_synonym="YNO1"
/db_xref="GeneID:852716"
mRNA 200561..202273
/gene="AIM14"
/locus_tag="YGL160W"
/gene_synonym="YNO1"
/product="Aim14p"
/transcript_id="NM_001181025.1"
/db_xref="GI:296144892"
/db_xref="GeneID:852716"
CDS 200561..202273
/gene="AIM14"
/locus_tag="YGL160W"
/gene_synonym="YNO1"
/note="NADPH oxidase localized to the perinuclear ER;
produces superoxide from NADPH; likely involved in
superoxide-mediated regulation of the actin cytoskeleton;
member of a conserved superfamily of NADPH oxidases (NOX
enzymes); has similarity to iron/copper reductases
(FRE1-8), particularly Fre8p"
/codon_start=1
/product="Aim14p"
/protein_id="NP_011355.1"
/db_xref="GI:6321278"
/db_xref="SGD:S000003128"
/db_xref="GeneID:852716"
/translation="MKESPLITLVKRHSETHFANIKYGYYVLIISLVYLIGLALLRAF
GRRTPSRSSSAFKNKIIYRLYDIDPAIHLGILFFAVLIPFYYHYSLTTQSTVYLKRLG
RLSYALIPLNLFLTLRPNWFLRKNCTYTDFIPFHKWFSRIITVIGLLHGIFFIIKWAI
DDNVSLKQKLILKTFNFAGFIISILVLFLLICSIGPMRRYNYRLFYIVHNLVNVAFIL
LTPIHSRPGVKFPFLLLNCTLLFIHIINRIVFAKSLMILNKNANYSKTNLVHVRLPRA
ILPDYFEPGSHIRISPYRRINPLYWLLPSHPYTIASLAEDNSIDLIIKETSTAEPGSQ
IESLRSNPKSFHLDQEKTYTLINSYPPSVPEECYSQGTNIAIICGGSGISFALPLFRH
FFNKENVKYLKMIWLIKDYSEYELVLDYLKTNGLTFEKKLSNNKRISVFISGEYTAET
RLDEITTNIDDENSEYEMGSFNNEDEDLSISNFNSENADSNDNTPETSHSPTKENGSM
IEVKSKHSFTLSNELKSFNNESAQVNQNETWLFSCGPPSLLQLSKKYCNDERINFVCE
TYGL"
gene 202721..203833
/locus_tag="YGL159W"
/db_xref="GeneID:852717"
mRNA 202721..203833
/locus_tag="YGL159W"
/product="hypothetical protein"
/transcript_id="NM_001181024.1"
/db_xref="GI:296144893"
/db_xref="GeneID:852717"
CDS 202721..203833
/locus_tag="YGL159W"
/note="hypothetical protein; deletion mutant has no
detectable phenotype"
/codon_start=1
/product="hypothetical protein"
/protein_id="NP_011356.1"
/db_xref="GI:6321279"
/db_xref="SGD:S000003127"
/db_xref="GeneID:852717"
/translation="MNNSIITDDEVREFYLNCSSQTIIESLLSLHESLRLYSQNHEIL
LNRMFKKLDETNADSNISHIFMPVVSKDFSGIKILVNNNNKNFQGVINVIEPETGKLI
GCFEAKQITAIRTALASCIGLYKQLSCSHDKLFRFENGTCYLTCFGTGLQAFWHIYIA
IKLIMSGIVGESLKLVEINILYHNNMMSLDRLKSLKNLFGSNIKIELNQYQINDISSE
GNGAVSNSDIIFGCLPTLEPNLFLRQLLNSKASVEQKHTYISLIGSYKPVMHECDKEL
IDKFKSDNESACILVDSREHTLLESGELIDSNIAPHNLIEIGELDTLKNTVLNLNEKG
CKRTITLCKIVGLAVMDVALAKEFLSLRTKNTENKE"
rep_origin 203914..204155
/note="ARS710;
Autonomously Replicating Sequence"
/db_xref="SGD:S000118454"
LTR 204982..205337
/note="Ty4 LTR"
/db_xref="SGD:S000006951"
gene 205521..205634
/locus_tag="tL(CAA)G1"
/db_xref="GeneID:852718"
tRNA join(205521..205558,205591..205634)
/locus_tag="tL(CAA)G1"
/product="tRNA-Leu"
/note="Leucine tRNA (tRNA-Leu), predicted by tRNAscan-SE
analysis"
/db_xref="SGD:S000006639"
/db_xref="GeneID:852718"
gene 207033..208571
/gene="RCK1"
/locus_tag="YGL158W"
/db_xref="GeneID:852719"
mRNA 207033..208571
/gene="RCK1"
/locus_tag="YGL158W"
/product="Rck1p"
/transcript_id="NM_001181023.1"
/db_xref="GI:296144894"
/db_xref="GeneID:852719"
CDS 207033..208571
/gene="RCK1"
/locus_tag="YGL158W"
/EC_number="2.7.11.1"
/note="Protein kinase involved in the response to
oxidative stress; identified as suppressor of S. pombe
cell cycle checkpoint mutations"
/codon_start=1
/product="Rck1p"
/protein_id="NP_011357.1"
/db_xref="GI:6321280"
/db_xref="SGD:S000003126"
/db_xref="GeneID:852719"
/translation="MSVNPEFIADGIDFYPTTPDAAYFNAADGKNKVNRINGNSENLH
HSFASGCRRSSLSVDFNVTSSDSEKSEQSCLENNSQEDEYFCDIFSTELKLDETSNKS
TDYSSSNHQYPEQLELHNYKLLNKIGEGAFSRVFKAVGINTDDQAPVAIKAIIKKGIS
SDAILKGNDRIQGSSRKKVLNEVAIHKLVSKNNPHCTKFIAFQESANYYYLVTELVTG
GEIFDRIVQLTCFSEDLARHVITQVAIAIKHMHYMGIVHRDVKPENLLFEPIPFYGLD
GDMQKEDEFTLGVGGGGIGLVKLMDFGLAKKLRNNTAKTPCGTIEYVASEVFTSKRYS
MKVDMWSIGCVLFTLLCGYPPFYEKNEKTLLKKISRGDYEFLAPWWDNISSGAKNAVT
HLLEVDPNKRYDIDDFLNDPWLNSYDCLKDSNSNSYASVQSILNDSFDERAETLHCAL
SCQSEKQDDTEFSRSESSEYIFMTEEDRNLRGSWIGEPKECFTLDLATSSIYRRRKNK
IFFW"
gene 209006..210049
/gene="ARI1"
/locus_tag="YGL157W"
/db_xref="GeneID:852720"
mRNA 209006..210049
/gene="ARI1"
/locus_tag="YGL157W"
/product="carbonyl reductase (NADPH-dependent) ARI1"
/transcript_id="NM_001181022.3"
/db_xref="GI:398364382"
/db_xref="GeneID:852720"
CDS 209006..210049
/gene="ARI1"
/locus_tag="YGL157W"
/EC_number="1.1.1.-"
/note="NADPH-dependent aldehyde reductase, utilizes
aromatic and alophatic aldehyde substrates; member of the
short-chain dehydrogenase/reductase superfamily"
/codon_start=1
/product="carbonyl reductase (NADPH-dependent) ARI1"
/protein_id="NP_011358.3"
/db_xref="GI:398364383"
/db_xref="SGD:S000003125"
/db_xref="GeneID:852720"
/translation="MTTDTTVFVSGATGFIALHIMNDLLKAGYTVIGSGRSQEKNDGL
LKKFNNNPKLSMEIVEDIAAPNAFDEVFKKHGKEIKIVLHTASPFHFETTNFEKDLLT
PAVNGTKSILEAIKKYAADTVEKVIVTSSTAALVTPTDMNKGDLVITEESWNKDTWDS
CQANAVAAYCGSKKFAEKTAWEFLKENKSSVKFTLSTINPGFVFGPQMFADSLKHGIN
TSSGIVSELIHSKVGGEFYNYCGPFIDVRDVSKAHLVAIEKPECTGQRLVLSEGLFCC
QEIVDILNEEFPQLKGKIATGEPATGPSFLEKNSCKFDNSKTKKLLGFQFYNLKDCIV
DTAAQMLEVQNEA"
gene 210416..213667
/gene="AMS1"
/locus_tag="YGL156W"
/db_xref="GeneID:852721"
mRNA 210416..213667
/gene="AMS1"
/locus_tag="YGL156W"
/product="Ams1p"
/transcript_id="NM_001181021.1"
/db_xref="GI:296144896"
/db_xref="GeneID:852721"
CDS 210416..213667
/gene="AMS1"
/locus_tag="YGL156W"
/EC_number="3.2.1.24"
/note="Vacuolar alpha mannosidase, involved in free
oligosaccharide (fOS) degradation; delivered to the
vacuole in a novel pathway separate from the secretory
pathway"
/codon_start=1
/product="Ams1p"
/protein_id="NP_011359.1"
/db_xref="GI:6321282"
/db_xref="SGD:S000003124"
/db_xref="GeneID:852721"
/translation="MSSEDIIYDPQFKPVQGIYENRLRQFIDTGGDYHDLNLPKFYDK
KRISLDHDHVKVWWYQVSFERGSSPVSPDKRPSWKSIIERDKKGELEFREANINQPFG
PSWSTTWFKVKISLPEDWVKSNEQLLFQWDCSNEGIVIDPKTLIPVTAFSGGERTEYV
LPKTSDGKHFFYIEAGNNGMFGCGAGSTINPPDDNRFFHLRKADIVWPDLDARALYID
FWMLGDAARELPGDSWQKHQARQLGNAVMNLFDPNDRSSVRKCRELLQREYFDSFLES
SKVYEQGESQVLTNVYGIGNCHIDTAWLWPFAETRRKIVRSWSSQCTLMDRFPEYKFV
ASQAQQFKWLLEDHPEFFNKVLIPKIQQSQFFAVGGTWVENDTNIPSGESLARQFFFG
QRFFLKHFGLKSKIFWLPDTFGYSSQMPQLCRLSGIDKFLTQKLSWNNINSFPHSTFN
WAGIDGSQLLTHMPPGNTYTADSHFGDVLRTAKQNKTPEYYGSGLMLYGKGDGGGGPT
EEMLQKMRRIRSMNNRNGNVIPKLQVGITVDEFYDDILKRTNQGHDLPTWSGELYFEF
HRGTYTSQAQTKKLMRLSEIKLHDLEWIAAKTSVLYPDSYKYPSKQINELWENVLLCQ
FHDVLPGSCIEMVYKYEAVPMLHNVVKECTSLIDKTVQFLQSQSKADLVEMRTLTWSK
PEKVSEECSLNGSYTSSVTGYDDYIVLANGKLKVIICKKTGVITSITDETLGVEYLDT
EHGRNKLGANQFVIYDDKPLGWQAWDTELYSVNQYKYVTKPKKVQVSCNTKEKCAVEV
IFQISEKCKIKSVISLNATAVTDAKLSKVDISTTVENWDARNKFLKVEFPVNIRNDFA
SYETQFGITKRPTHYNTSWDVAKFEVCHHKFADYSEYSKGVSILNDCKYGFSTHGNLM
RLSLLRSPKAPDAHADMGTHEIKYAIYPHRGALSSDTVKLAHEFNYCFKYKLPKDIGM
NFDDIISISGDENVILSNIKRGEDDSAVKSNYSLNPRDEQSIVVRVYESLGGESFASL
NTTLNLKRIEKVDNLEMKVYKSLTATRDESNHAINRIPIKLRPFEIASFRLYF"
gene 214081..215211
/gene="CDC43"
/locus_tag="YGL155W"
/gene_synonym="CAL1"
/db_xref="GeneID:852722"
mRNA 214081..215211
/gene="CDC43"
/locus_tag="YGL155W"
/gene_synonym="CAL1"
/product="protein geranylgeranyltransferase type I subunit
CDC43"
/transcript_id="NM_001181020.1"
/db_xref="GI:296144897"
/db_xref="GeneID:852722"
CDS 214081..215211
/gene="CDC43"
/locus_tag="YGL155W"
/gene_synonym="CAL1"
/EC_number="2.5.1.59"
/note="Beta subunit of geranylgeranyltransferase type I,
catalyzes geranylgeranylation to the cysteine residue in
proteins containing a C-terminal CaaX sequence ending in
Leu or Phe; has substrates important for morphogenesis"
/codon_start=1
/product="protein geranylgeranyltransferase type I subunit
CDC43"
/protein_id="NP_011360.1"
/db_xref="GI:6321283"
/db_xref="SGD:S000003123"
/db_xref="GeneID:852722"
/translation="MCQATNGPSRVVTKKHRKFFERHLQLLPSSHQGHDVNRMAIIFY
SISGLSIFDVNVSAKYGDHLGWMRKHYIKTVLDDTENTVISGFVGSLVMNIPHATTIN
LPNTLFALLSMIMLRDYEYFETILDKRSLARFVSKCQRPDRGSFVSCLDYKTNCGSSV
DSDDLRFCYIAVAILYICGCRSKEDFDEYIDTEKLLGYIMSQQCYNGAFGAHNEPHSG
YTSCALSTLALLSSLEKLSDKFKEDTITWLLHRQVSSHGCMKFESELNASYDQSDDGG
FQGRENKFADTCYAFWCLNSLHLLTKDWKMLCQTELVTNYLLDRTQKTLTGGFSKNDE
EDADLYHSCLGSAALALIEGKFNGELCIPQEIFNDFSKRCCF"
gene complement(215278..216096)
/gene="LYS5"
/locus_tag="YGL154C"
/db_xref="GeneID:852723"
mRNA complement(215278..216096)
/gene="LYS5"
/locus_tag="YGL154C"
/product="Lys5p"
/transcript_id="NM_001181019.1"
/db_xref="GI:296144898"
/db_xref="GeneID:852723"
CDS complement(215278..216096)
/gene="LYS5"
/locus_tag="YGL154C"
/EC_number="1.2.1.31"
/note="Phosphopantetheinyl transferase involved in lysine
biosynthesis; converts inactive apo-form of Lys2p
(alpha-aminoadipate reductase) into catalytically active
holo-form by posttranslational addition of
phosphopantetheine"
/codon_start=1
/product="Lys5p"
/protein_id="NP_011361.1"
/db_xref="GI:6321284"
/db_xref="SGD:S000003122"
/db_xref="GeneID:852723"
/translation="MVKTTEVVSEVSKVAGVRPWAGIFVVEIQEDILADEFTFEALMR
TLPLASQARILNKKSFHDRCSNLCSQLLQLFGCSIVTGLNFQELKFDKGSFGKPFLDN
NRFLPFSMTIGEQYVAMFLVKCVSTDEYQDVGIDIASPCNYGGREELELFKEVFSERE
FNGLLKASDPCTIFTYLWSLKESYTKFTGTGLNTDLSLIDFGAISFFPAEGASMCITL
DEVPLIFHSQWFNNEIVTICMPKSISDKINTNRPKLYNISLSTLIDYFIENDGL"
gene 216273..217298
/gene="PEX14"
/locus_tag="YGL153W"
/db_xref="GeneID:852724"
mRNA 216273..217298
/gene="PEX14"
/locus_tag="YGL153W"
/product="Pex14p"
/transcript_id="NM_001181018.3"
/db_xref="GI:398364394"
/db_xref="GeneID:852724"
CDS 216273..217298
/gene="PEX14"
/locus_tag="YGL153W"
/note="Peroxisomal membrane peroxin that is a central
component of the peroxisomal protein import machinery;
interacts with both PTS1 (Pex5p) and PTS2 (Pex7p),
peroxisomal matrix protein signal recognition factors and
membrane receptor Pex13p"
/codon_start=1
/product="Pex14p"
/protein_id="NP_011362.3"
/db_xref="GI:398364395"
/db_xref="SGD:S000003121"
/db_xref="GeneID:852724"
/translation="MSDVVSKDRKALFDSAVSFLKDESIKDAPLLKKIEFLKSKGLTE
KEIEIAMKEPKKDGIVGDEVSKKIGSTENRASQDMYLYEAMPPTLPHRDWKDYFVMAT
ATAGLLYGAYEVTRRYVIPNILPEAKSKLEGDKKEIDDQFSKIDTVLNAIEAEQAEFR
KKESETLKELSDTIAELKQALVQTTRSREKIEDEFRIVKLEVVNMQNTIDKFVSDNDG
MQELNNIQKEMESLKSLMNNRMESGNAQDNRLFSISPNGIPGIDTIPSASEILAKMGM
QEESDKEKENGSDANKDDNAVPAWKKAREQTIDSNASIPEWQKNTAANEISVPDWQNG
QVEDSIP"
gene 217524..220922
/gene="NUT1"
/locus_tag="YGL151W"
/gene_synonym="MED5"
/db_xref="GeneID:852726"
mRNA 217524..220922
/gene="NUT1"
/locus_tag="YGL151W"
/gene_synonym="MED5"
/product="Nut1p"
/transcript_id="NM_001181016.1"
/db_xref="GI:296144900"
/db_xref="GeneID:852726"
CDS 217524..220922
/gene="NUT1"
/locus_tag="YGL151W"
/gene_synonym="MED5"
/note="Component of the RNA polymerase II mediator
complex, which is required for transcriptional activation
and also has a role in basal transcription"
/codon_start=1
/product="Nut1p"
/protein_id="NP_011364.1"
/db_xref="GI:6321287"
/db_xref="SGD:S000003119"
/db_xref="GeneID:852726"
/translation="MEKESVYNLALKCAERQLTSMEFSNLYKEFFNEKFPSLIQEEEE
DTTTTANINEVKKASDLVDTPSNNTAATADTTHLHEALDIVCSDFVKILNLEKPLILA
DYIVEVLLVNYNSDMIKCFLPKLNSVRNSLLLAHFFSKSCSFFAKLSDTLIIDQVRKD
LGNVIVPNILSLDMNSMNKELIAIVSKLLQTTLKLSPSPILLTSAGCKNGSFTLLNQL
SQTNKLLFKRVSQTFEAKLHFKDTKPFLNKDSTNEFVGSPSLTSPQYIPSPLSSTKPP
GSVNSAAKYKDMKLLRYYKNIWLNNKIINWEISNPDFLSKYSAITSSIFQESFNSVQN
LDQLLTDLIETSFTCFAQFVSNKQYHQANSNLTLLERKWVIFITKHLPLLILENSSRS
PRVVTNALDNIDEKVVKAIRIYFTEKDDNKTNNEDLFDDYPSTSLDIRHDFIKGLIML
NLQPASVINNYLREDQMIDTSILPTRDDLFVRNLQGIQEVVHNTNSFIISSLDTLELE
SITESITHDSSNGLFQVLHNFESVAPTKQREIVKAFLSIFEDAIKELNYNRIAKICAL
LFFNFSHSLTTILSFSSPAALMKTLIKFVDLSRNGRNGSNGNDESSEYETINISLSFS
WAILLIINLTQTYGISVVDVALKYPELSIKNSFIINFISNLPNVSDKYYLEESNVNDS
DMLTKSHNTVQSWLCDLFVNGSITDQLIQNIETRQLANLIPFIVKQVLLSVEIGVLTD
ISSLIGGFEYFLQPLLLVGLIKTFYWLEQFLSCVKNDTISEDILQGIFNLLNTLFNPV
TLNEDSKAFHTAVLRLNAIPLLKVLRKFRVQSQSNYGIYSSDAQGDPNLEPLIAKLVA
VLNVSPVYDVDPRIINSENDYSRKQLGYGKFLILNENPINKIMTNQINSFWSLHSSTY
YNLDYLFELIELVTPKSFLFDVLKTLEYKLATYGVPGSENKRGSLDSEHVFDYFFYFL
VLYDVKTAEEASQLIEYMENDAKKSKGDVDIKGEDLHEKNDSAEVRQETQPKAEATQD
DDFDMLFGENDTSTQAYEEEEENEDNDGNNRTNNVPMIKAEETPSKTNKISILKRHSF
AVLLHERKLLNDLALENGEITKTENEKFISYHDKYLCMLKTCVF"
gene complement(221104..225573)
/gene="INO80"
/locus_tag="YGL150C"
/db_xref="GeneID:852728"
mRNA complement(221104..225573)
/gene="INO80"
/locus_tag="YGL150C"
/product="chromatin-remodeling ATPase INO80"
/transcript_id="NM_001181015.1"
/db_xref="GI:296144901"
/db_xref="GeneID:852728"
CDS complement(221104..225573)
/gene="INO80"
/locus_tag="YGL150C"
/EC_number="3.6.1.-"
/note="ATPase and nucleosome spacing factor, subunit of
complex containing actin and actin-related proteins that
has chromatin remodeling activity and 3' to 5' DNA
helicase activity in vitro; has a role in modulating
stress gene transcription"
/codon_start=1
/product="chromatin-remodeling ATPase INO80"
/protein_id="NP_011365.1"
/db_xref="GI:6321289"
/db_xref="SGD:S000003118"
/db_xref="GeneID:852728"
/translation="MSLAVLLNKEDKDISDFSKTTAGKSAKKNSRERVADVAPTRVLD
KKQAYLSQLNSEFNRIKRRDSIEQLYQDWKFINLQEFELISEWNQQSKDWQFDNTNDS
QDLHFKKLYRDMSMINKEWAEYQSFKNANLSDIINEKDADEDEEDDEDELEDGEEDME
EDEASTGRHTNGKSMRGNGIQKSRKKDAAAAAAIGKAIKDDQTHADTVVTVNGDENED
GNNGEDEDNDNDNENNNDNDNDNENENDNDSDNDDEEENGEEDEEEEEIEDLDEEDFA
AFEEQDDNDDEDFNPDVEKRRKRSSSSSSSTKLSMNSLSLITSKKINKNITINSDRPK
IVRELIKMCNKNKHQKIKKRRFTNCIVTDYNPIDSKLNIKITLKQYHVKRLKKLINDA
KREREREEALKNNVGLDGNDLDNDEDGSESHKRRKLNNNTANGADDANKRKFNTRHGL
PTYGMKMNAKEARAIQRHYDNTYTTIWKDMARKDSTKMSRLVQQIQSIRSTNFRKTSS
LCAREAKKWQSKNFKQIKDFQTRARRGIREMSNFWKKNEREERDLKKKIEKEAMEQAK
KEEEEKESKRQAKKLNFLLTQTELYSHFIGRKIKTNELEGNNVSSNDSESQKNIDISA
LAPNKNDFHAIDFDNENDEQLRLRAAENASNALAETRAKAKQFDDHANAHEEEEEEDE
LNFQNPTSLGEITIEQPKILACTLKEYQLKGLNWLANLYDQGINGILADEMGLGKTVQ
SISVLAHLAENHNIWGPFLVVTPASTLHNWVNEISKFLPQFKILPYWGNANDRKVLRK
FWDRKNLRYNKNAPFHVMVTSYQMVVTDANYLQKMKWQYMILDEAQAIKSSQSSRWKN
LLSFHCRNRLLLTGTPIQNSMQELWALLHFIMPSLFDSHDEFNEWFSKDIESHAEANT
KLNQQQLRRLHMILKPFMLRRVKKNVQSELGDKIEIDVLCDLTQRQAKLYQVLKSQIS
TNYDAIENAATNDSTSNSASNSGSDQNLINAVMQFRKVCNHPDLFERADVDSPFSFTT
FGKTTSMLTASVANNNSSVISNSNMNLSSMSSNNISNGKFTDLIYSSRNPIKYSLPRL
IYEDLILPNYNNDVDIANKLKNVKFNIFNPSTNYELCLFLSKLTGEPSLNEFFRVSTT
PLLKRVIERTNGPKNTDSLSFKTITQELLEVTRNAPSEGVMASLLNVEKHAYEREYLN
CIQRGYHPNVSAPPVTIEVLGSSHVTNSINNELFDPLISQALSDIPAITQYNMHVKKG
IPVEDFPKTGLFPEPLNKNFSSNISMPSMDRFITESAKLRKLDELLVKLKSEGHRVLI
YFQMTKMMDLMEEYLTYRQYNHIRLDGSSKLEDRRDLVHDWQTNPEIFVFLLSTRAGG
LGINLTAADTVIFYDSDWNPTIDSQAMDRAHRLGQTRQVTVYRLLVRGTIEERMRDRA
KQKEQVQQVVMEGKTQEKNIKTIEVGENDSEVTREGSKSISQDGIKEAASALA"
gene 226399..227529
/gene="ARO2"
/locus_tag="YGL148W"
/db_xref="GeneID:852729"
mRNA 226399..227529
/gene="ARO2"
/locus_tag="YGL148W"
/product="bifunctional chorismate synthase/riboflavin
reductase [NAD(P)H] ARO2"
/transcript_id="NM_001181013.1"
/db_xref="GI:296144902"
/db_xref="GeneID:852729"
CDS 226399..227529
/gene="ARO2"
/locus_tag="YGL148W"
/EC_number="4.2.3.5"
/note="Bifunctional chorismate synthase and flavin
reductase; catalyzes the conversion of
5-enolpyruvylshikimate 3-phosphate (EPSP) to form
chorismate, which is a precursor to aromatic amino acids;
protein abundance increases in response to DNA replication
stress"
/codon_start=1
/product="bifunctional chorismate synthase/riboflavin
reductase [NAD(P)H] ARO2"
/protein_id="NP_011367.1"
/db_xref="GI:6321290"
/db_xref="SGD:S000003116"
/db_xref="GeneID:852729"
/translation="MSTFGKLFRVTTYGESHCKSVGCIVDGVPPGMSLTEADIQPQLT
RRRPGQSKLSTPRDEKDRVEIQSGTEFGKTLGTPIAMMIKNEDQRPHDYSDMDKFPRP
SHADFTYSEKYGIKASSGGGRASARETIGRVASGAIAEKFLAQNSNVEIVAFVTQIGE
IKMNRDSFDPEFQHLLNTITREKVDSMGPIRCPDASVAGLMVKEIEKYRGNKDSIGGV
VTCVVRNLPTGLGEPCFDKLEAMLAHAMLSIPASKGFEIGSGFQGVSVPGSKHNDPFY
FEKETNRLRTKTNNSGGVQGGISNGENIYFSVPFKSVATISQEQKTATYDGEEGILAA
KGRHDPAVTPRAIPIVEAMTALVLADALLIQKARDFSRSVVH"
gene complement(227754..228329)
/gene="RPL9A"
/locus_tag="YGL147C"
/db_xref="GeneID:852730"
mRNA complement(227754..228329)
/gene="RPL9A"
/locus_tag="YGL147C"
/product="ribosomal 60S subunit protein L9A"
/transcript_id="NM_001181012.3"
/db_xref="GI:398364406"
/db_xref="GeneID:852730"
CDS complement(227754..228329)
/gene="RPL9A"
/locus_tag="YGL147C"
/note="Ribosomal 60S subunit protein L9A; nearly identical
to Rpl9Bp; homologous to mammalian ribosomal protein L9
and bacterial L6"
/codon_start=1
/product="ribosomal 60S subunit protein L9A"
/protein_id="NP_011368.3"
/db_xref="GI:398364407"
/db_xref="SGD:S000003115"
/db_xref="GeneID:852730"
/translation="MKYIQTEQQIEVPEGVTVSIKSRIVKVVGPRGTLTKNLKHIDVT
FTKVNNQLIKVAVHNGGRKHVAALRTVKSLVDNMITGVTKGYKYKMRYVYAHFPINVN
IVEKDGAKFIEVRNFLGDKKIRNVPVRDGVTIEFSTNVKDEIVLSGNSVEDVSQNAAD
LQQICRVRNKDIRKFLDGIYVSHKGFITEDL"
gene complement(228751..229686)
/gene="RRT6"
/locus_tag="YGL146C"
/db_xref="GeneID:852731"
mRNA complement(228751..229686)
/gene="RRT6"
/locus_tag="YGL146C"
/product="Rrt6p"
/transcript_id="NM_001181011.1"
/db_xref="GI:296144904"
/db_xref="GeneID:852731"
CDS complement(228751..229686)
/gene="RRT6"
/locus_tag="YGL146C"
/note="hypothetical protein; non-essential gene identified
in a screen for mutants with increased levels of rDNA
transcription; contains two putative transmembrane spans,
but no significant homology to other known proteins"
/codon_start=1
/product="Rrt6p"
/protein_id="NP_011369.1"
/db_xref="GI:6321292"
/db_xref="SGD:S000003114"
/db_xref="GeneID:852731"
/translation="MEKASLNIAQTKEIPLTDRRMGLRGWKACSRPHLLGRILLFMSI
LFITSAELSSDVSSREVYMPIFNNKLSFKVPPIKRSLLLGAALYEDFEYSSNNSASDG
AFCTVFNAGMNDASREVVFEIHVMDVLQEETDSSRFGGTSHERGRQSLGFSVFNNKNG
DLLRSKKNLASGTSVIEVNPGNCNEFLICFINLVYDGSWSSIDTEKSVTIKMTYNDKL
DPDMLLHLVNQMTPQVVKALNTVSDGLFQIVSDTTLLQMESDRRDINEATYSYLIVGF
VSLMVAQLISNIIVTTYLIIKIKSNPSSHIKKKGL"
gene 230243..232348
/gene="TIP20"
/locus_tag="YGL145W"
/gene_synonym="TIP1"
/db_xref="GeneID:852732"
mRNA 230243..232348
/gene="TIP20"
/locus_tag="YGL145W"
/gene_synonym="TIP1"
/product="Tip20p"
/transcript_id="NM_001181010.2"
/db_xref="GI:330443547"
/db_xref="GeneID:852732"
CDS 230243..232348
/gene="TIP20"
/locus_tag="YGL145W"
/gene_synonym="TIP1"
/note="Peripheral membrane protein required for fusion of
COPI vesicles with the ER; prohibits back-fusion of COPII
vesicles with the ER; forms a tethering complex with
Sec39p and Dsl1p that interacts with ER SNAREs Sec20p and
Use1p"
/codon_start=1
/product="Tip20p"
/protein_id="NP_116577.1"
/db_xref="GI:14318435"
/db_xref="SGD:S000003113"
/db_xref="GeneID:852732"
/translation="MNGIDDLLNINDRIKQVQNERNELASKLQNLKQSLASNDTEVAL
SEVIAQDIIEVGASVEGLEQLRAKYGDLQILNKLEKVAVQQTQMQAGVDKLDSFERQL
DELAEQPPDQFTLDDVKALHSKLTSVFATVPQINNIDSQYAAYNKLKSKVTGKYNDVI
IQRLATNWSNTFDQKLLEAQWDTQKFASTSVGLVKCLRENSTKLYQLSLLYLPLEEET
QNGDSERPLSRSNNNQEPVLWNFKSLANNFNVRFTYHFHATSSSSKIETYFQFLNDYL
AENLYKCINIFHDDCNGLTKPVIHEQFINYVLQPIRDKVRSTLFQNDLKTLIVLISQI
LATDKNLLNSFHYHGLGLVSLISDEVWEKWINYEVEMANRQFINITKNPEDFPKSSQN
FVKLINKIYDYLEPFYDLDFDLLVRYKLMTCSLIFMNLTSSYLDYILTVDSLNETRTK
EQELYQTMAKLQHVNFVYRKIKSLSSNFIFIQLTDIVNSTESKKYNSLFQNVENDYEK
AMSTDMQNSIVHRIQKLLKETLRNYFKISTWSTLEMSVDENIGPSSVPSAELVNSINV
LRRLINKLDSMDIPLAISLKVKNELLNVIVNYFTESILKLNKFNQNGLNQFLHDFKSL
SSILSLPSHATNYKCMSLHELVKILKLKYDPNNQQFLNPEYIKTGNFTSLKEAYSIKY
LKDTKIQDALYRIIYGNIL"
rep_origin 231907..231981
/gene="TIP20"
/locus_tag="YGL145W"
/gene_synonym="TIP1"
/note="ARS701;
Autonomously Replicating Sequence that contains only an
imperfect match to the core consensus sequence"
/db_xref="SGD:S000007642"
gene complement(232450..234507)
/gene="ROG1"
/locus_tag="YGL144C"
/db_xref="GeneID:852733"
mRNA complement(232450..234507)
/gene="ROG1"
/locus_tag="YGL144C"
/product="putative lipase ROG1"
/transcript_id="NM_001181009.1"
/db_xref="GI:296144906"
/db_xref="GeneID:852733"
CDS complement(232450..234507)
/gene="ROG1"
/locus_tag="YGL144C"
/EC_number="3.1.-.-"
/note="Protein with putative serine active lipase domain;
ROG1 has a paralog, YDL109C, that arose from the whole
genome duplication"
/codon_start=1
/product="putative lipase ROG1"
/protein_id="NP_011371.1"
/db_xref="GI:6321294"
/db_xref="SGD:S000003112"
/db_xref="GeneID:852733"
/translation="MSLTPTNEILFHYKSSVKVGELERYVITYHLYDGEEIPPDLNLN
SLWLKVRNMNPLSYRAAYLMGPFMLYCDVKTAQYHHSQKIVASVDYPKFEPNVQTQQD
FVAELSVHNIRQKYVWIADVMSQILFTTNTNVTYEVTIGTSKESVENPHDLPSHLGSY
SPKLTVNRLTTLDLWNLPVQITTPQKKKHLVVLTHGLHSNVSTDLVYIMEQIYKAQKN
YPHEQIVVKGYRGNVCQTEKGVKYLGTRLAEYIIQDLYDESIRKISFVGHSLGGLIQA
FAIAYIYEVYPWFFKKVNPINFITLASPLLGIVTDNPAYIKVLLSFGVIGKTGQDLGL
ENDVEVGKPLLYLLSGLPLIEILRRFKRRTVYANAINDGIVPLYTASLLFLDYNDILE
QLQKLKENSKKSPLINDASTPVNQDFFNKTFISPLTKMLSILAPQKFPTENGSEIPKV
SFFESASSILLPPLPERAYIMDPDSRDPVIIHDKIYNEDDIPQSEFDIEDGFFGKKNI
LLQAFFAGKKERAKYRNLEETIARRWHEGMAWRKVVVALKPDAHNNIIVRRKFANAYG
WPVIDHLIDVHFNGDDDDDNDENDDINSTQVVEPIQSVTEGKKKYRKAENIPQEYGWL
NKVETNGVFDEGPTGMISTVGEIVEALAKRGFSAVIDRRNASEDPNDEVLRFEEMNSD
LVQ"
gene complement(234717..235958)
/gene="MRF1"
/locus_tag="YGL143C"
/db_xref="GeneID:852734"
mRNA complement(234717..235958)
/gene="MRF1"
/locus_tag="YGL143C"
/product="Mrf1p"
/transcript_id="NM_001181008.3"
/db_xref="GI:398364418"
/db_xref="GeneID:852734"
CDS complement(234717..235958)
/gene="MRF1"
/locus_tag="YGL143C"
/note="Mitochondrial translation release factor, involved
in stop codon recognition and hydrolysis of the
peptidyl-tRNA bond during mitochondrial translation; lack
of MRF1 causes mitochondrial genome instability"
/codon_start=1
/product="Mrf1p"
/protein_id="NP_011372.3"
/db_xref="GI:398364419"
/db_xref="SGD:S000003111"
/db_xref="GeneID:852734"
/translation="MWLSKFQFPSRSIFKGVFLGHKLPLLVRLTSTTTNSKSNGSIPT
QYTELSPLLVKQAEKYEAELKDLDKDLSCGIHFDVNKQKHYAKLSALTDTFIEYKEKL
NELKSLQEMIVSDPSLRAEAEQEYAELVPQYETTSSRLVNKLLPPHPFADKPSLLELR
PGVGGIEAMIFTQNLLDMYIGYANYRKWKYRIISKNENESGSGIIDAILSIEEAGSYD
RLRFEAGVHRVQRIPSTETKGRTHTSTAAVVVLPQIGDESAKSIDAYERTFKPGEIRV
DIMRASGKGGQHVNTTDSAVRLTHIPSGIVVSMQDERSQHKNKAKAFTILRARLAEKE
RLEKEEKERKARKSQVSSTNRSDKIRTYNFPQNRITDHRCGFTLLDLPGVLSGERLDE
VIEAMSKYDSTERAKELLESN"
gene complement(236269..238119)
/gene="GPI10"
/locus_tag="YGL142C"
/db_xref="GeneID:852735"
mRNA complement(236269..238119)
/gene="GPI10"
/locus_tag="YGL142C"
/product="Gpi10p"
/transcript_id="NM_001181007.1"
/db_xref="GI:296144908"
/db_xref="GeneID:852735"
CDS complement(236269..238119)
/gene="GPI10"
/locus_tag="YGL142C"
/EC_number="2.4.1.-"
/note="Integral membrane protein involved in
glycosylphosphatidylinositol (GPI) anchor synthesis;
putative alpha 1,2 mannosyltransferase required for
addition of the third mannose onto the GPI core structure;
human PIG-Bp is a functional homolog"
/codon_start=1
/product="Gpi10p"
/protein_id="NP_011373.1"
/db_xref="GI:6321296"
/db_xref="SGD:S000003110"
/db_xref="GeneID:852735"
/translation="MAHEVHRIKPKLGRTQIFWVFLAFRVLNAVLTRTFFQADEFWQA
LEPAHWKAFKYGELTWEWKFGVRSYLFPMIFELTYRLVSLSSILLHYALLLLSTIGSD
LLILLLPKYELSWQVAEDLKRLPFDVTRSFEYYGVIYAPKIVMAVLASIGEYYIVRFV
QKLYLLTLDKRNEKEEEERRSGLSEITKFALLLSLTNFFNCFFITRTFINSFEMILTS
IALYYWDWTGGQMIKESSFTKSLIFAFLACLQRPSSGLIWVIPSISLILNLVGKKQYH
LLFITFSKVLRSFFLVFTANAIIDMYFYEKVTFPFFRFLKFNFTTPLSKFYGVAPWHF
HFFQSLPIVLGASIPAFAFGLFFPLSKRSFPKKYLNPFFQVKLTILLNLLVYSTLPHK
EFRFIFPLQPLFILISSFGLLRLDRDYWKRLSGLKSLLWLVPFVSVFIALLLDTFHES
GSIEVMKFLHEEPEIDSLGFIMPCHSTPGQSYLHRSDIQDLWSITCNPPLHLLGDPEA
YSKLETYMDESDHLYDDISAFIYKNFPPPFRKDLRSPGKTYSHEWPTYLVVFEHMENA
FLKDFLKDSSYIEYNRFFNSLAHWDSRRSGDIIIYYKLPFDYSDIPAADI"
gene 238353..241085
/gene="HUL5"
/locus_tag="YGL141W"
/db_xref="GeneID:852736"
mRNA 238353..241085
/gene="HUL5"
/locus_tag="YGL141W"
/product="ubiquitin-ubiquitin ligase HUL5"
/transcript_id="NM_001181006.1"
/db_xref="GI:296144909"
/db_xref="GeneID:852736"
CDS 238353..241085
/gene="HUL5"
/locus_tag="YGL141W"
/EC_number="6.3.2.-"
/note="Multiubiquitin chain assembly factor (E4);
proteasome processivity factor that elongates polyUb
chains on substrates, opposing Ubp6p, a branched
polyubiquitin protease; required for retrograde transport
of misfolded proteins during ERAD"
/codon_start=1
/product="ubiquitin-ubiquitin ligase HUL5"
/protein_id="NP_011374.1"
/db_xref="GI:6321297"
/db_xref="SGD:S000003109"
/db_xref="GeneID:852736"
/translation="MLNFTGQTRRRNVNLGNRTRNSKKDLLEKAKRERERRAQDKLKE
DASKTIQKSIRRHFSNVRLFKNTFTSSQLVHMIPAYGGKLIYYISQYDLQQLLKLSHN
FLSSYPNSLGNRQLLSLLKLYQDDALVAETLSDLNMDCPTVDEFLDSLSVYLCRASFL
SYSSASKLADVIEAWEVMHSSASISIFSISIGSYEKRPFALQFYCILAERNLLPQLIN
TNPILWDNMAKTYSHCSKGGQKNIAKLLIPNFNNHIAPSVLRSDNDYVLKFYEKAFID
EVIATTANYVSDEDHVKNLMCYIASSPNQSCKNSVLITLLSNKDFVRRLSWEFFHTKF
NASKTEAHPLFSVLAQLIDMHLLISTDRELLDYNSVIPIEELKKFTSTLKDFTFRQYW
ELPKSERNPMLKEAVPLLSKVYERDSRLHFLSTENNPTYWENSEKQFLNLRFYEELQE
YEDLYREHLEEESDEDMEKEIDLDKERPPLKSLLLNKMKKRLKSSLRFRKLEILLELP
FFIPFEERVDLFYMFIALDKKRLSLDDDHNLINMFTPWASTGMRKQSAIISRDNVLED
AFNAFNSIGERFKASLDVTFINEFGEEAGIDGGGITKEFLTTVSDEGFKDPKHELFRT
NDRYELYPSVVYDATKLKYIWFLGKVVGKCLYEHVLIDVSFADFFLKKLLNYSNGFLS
SFSDLGSYDSVLYNNLIKLLNMTTDEIKSLDLTFEIDEPESSAKVVDLIPNGSKTYVT
KDNVLLYVTKVTDYKLNKRCFKPVSAFHGGLSVIIAPHWMEMFNSIELQMLISGERDN
IDLDDLKSNTEYGGYKEEDQTIVDFWEVLNEFKFEEKLNFLKFVTSVPQAPLQGFKAL
DPKFGIRNAGTEKYRLPTASTCVNLLKLPDYRNKTILREKLLYAINSGARFDLS"
rep_origin 241085..241353
/note="ARS712;
Replication origin; identified in multiple array studies,
confirmed by plasmid-based recombinational ARS assay"
/db_xref="SGD:S000130164"
gene complement(241353..245012)
/locus_tag="YGL140C"
/db_xref="GeneID:852737"
mRNA complement(241353..245012)
/locus_tag="YGL140C"
/product="hypothetical protein"
/transcript_id="NM_001181005.1"
/db_xref="GI:296144910"
/db_xref="GeneID:852737"
CDS complement(241353..245012)
/locus_tag="YGL140C"
/note="hypothetical protein; non-essential gene; contains
multiple predicted transmembrane domains"
/codon_start=1
/product="hypothetical protein"
/protein_id="NP_011375.1"
/db_xref="GI:6321298"
/db_xref="SGD:S000003108"
/db_xref="GeneID:852737"
/translation="MSLKSKLTKIQKLWLYYFPCDRILAKRICKSTVNTTVAFIFCLI
PKITAHLGAAPAMLPMISVIVHPGRRVGGTIHGAIYCITGLIFGLAYAIFGRFLAQRC
LGSSWHELTEAQQHVLHYKRYEAGLAILAVFEVIMLFFHGWMRSVSHYYFGIVFPLFV
VVHFAFMDPLNETAGTIAKAYSTPFYLGIAMSIFWNLVLFPEWGTTYLGNTTIDAMNE
LHKSIDYSINFFIAVDPHNSSQLYSRDPVSLGKLLKMKSLISSKVNNCRVVLHECIYE
FTYAYVSPTKLKPIISTLENLTVFINGLVNTCQLEFILLARHDNKLRPDDVAALTLPK
NKEISFANAEKLLKVIDKLHPVIYSLHRTMSECMYIAKLVLAHAFDVKVSRVHSCSMF
KDGNFPTFSNNANNLPNDVDIQNKINDLKQALEECKAKFKSEMLSFDIDIMSPSDEMF
LLSSFLLNFRQTADSTLVIMESVKDILVKRQIQEKKGWLRGKRLWFLVLTNYETFSIW
LKGDRNSVTENDTLKGTFNGNTNGFAHDTVIRRPDYEENELLSQKVSSNKNIVKDDAS
LDLPMTSEPKGNSSSTSDTSSSPLTLTKTTTFGTNRTSRRQGRFSFMSMLISIDKFCE
VSHPHFRFGFQVAIALMLASFPMFIPKTRQWYIDYRGTWIGFVCILCLEPSVGGTFWV
FFLRAVGVIFGAAWGYLSYVAAVNQTNPYLETVITVFGAIPGFYYLLGTPYVKAAIIE
IISIYIVMLAAILPSQDDILTSFAKRCLAVGYGGGVALIVQVFFFPLKAREQLNEEIS
FVCGCISEMELLYATGLEGEQVASSMSEEKYKKIEKISKSAKEALARATAYKGLTRQE
PRLKGEYTELENVFTQVIFIQKQIIERIDTISLLRKQNGSAVIEEFNSVVYPYRRQMV
GSISCLMRALQEAFINKTPLPQFLPSARIAHRRLINKVRQTLRIRYPGQISNLSDKAR
KPNEGDYADGKDEDDDDNEGLVMKMNRRGQANTTANPHEYVLKEKFLSWNASSAASEE
IIEYIEELLNLTKILVGVNEFKYGFLSRPLYEDWAAEAVTGFDNFINGKSNPMNTRRN
RTPFDGTSIISEGNESLQSTNSNESQISPDSTRSYEPECPVAYEKNDNPAALNLLRIA
SHKAGQNADGLPKTFRNRAFSITSTSGQLSSLSRHSTLGNADPNYLNDDDESSDDDLP
LALKMVLSHMKEKKD"
gene 245716..248124
/gene="FLC3"
/locus_tag="YGL139W"
/db_xref="GeneID:852738"
mRNA 245716..248124
/gene="FLC3"
/locus_tag="YGL139W"
/product="Flc3p"
/transcript_id="NM_001181004.3"
/db_xref="GI:398364428"
/db_xref="GeneID:852738"
CDS 245716..248124
/gene="FLC3"
/locus_tag="YGL139W"
/note="Putative FAD transporter, similar to Flc1p and
Flc2p; localized to the ER"
/codon_start=1
/product="Flc3p"
/protein_id="NP_011376.3"
/db_xref="GI:398364429"
/db_xref="SGD:S000003107"
/db_xref="GeneID:852738"
/translation="MRFLQVYKSSALIGLIILLASKVNLAEAKRKLVATSLVTCMENS
QLSANSFDVVFNPDDRSLHYDLDMSTQIDSYIFADIDVYAYGFKIITKNVDLCSINWK
QFCPVHPGNIQIDSIEYISSEYVNEIPGIAYQVPDIDAYARVKITNNVSEYLACIQIY
FSNGKTVSQIGVKWATAVVAGIGLLLSAILSTFGNSTAASHISANTMSLFLYFQSVVV
VAMQHVHRVPPIAAAWAENLVWSMGLIRISFMQRIFRWYVQSTGGTPSLYLTSTSMSV
LAQRSWQYLMELPLIKRATNVLYGNANTLIFRGIKRLGYKMGIENTSIVCTGFTFFVL
CGYVLAGFIIVFKCCVELATRLGWIQKARFWEFRKQWRMILKGALLRYIYIGFVQLTI
LSFWEFTERDSPAVIVIACLFILLSCGLMLWAAWRTVFFARRSVALYNNPAALLYGDE
YVLHKYGFFYTMFNANHYWWNIVLLSYIFVKSLLVGFAQASGQTQVLFMFILDLFYFV
AIIYYKPYLDRPTNIMNILIATVTVVNSFLFMFFSDLFNQSYKVAAIMGWIFFIMNAA
FSFILLMMILAFAGMMLFSKNPDLRFKPAKDDRTSFQRNTMKPEGTVNRSVANELLAL
GNVAKDHDDNSDYESNDTGVNDELKQAQDETTPTTVTSSDDNKPTFSEKILSKFSRPK
NENASTDALRVEAPKQQTFPHNLTNLSRENLSTLGSKPYPGHTRSQSDAHNGLINSFE
EEDTSSNTDPFHDSTEGDLLDTSSSDGGFRSQNYVRDDSINSLGNNKQPLRKPPGFFD
EGFM"
gene complement(248494..249531)
/locus_tag="YGL138C"
/db_xref="GeneID:852739"
mRNA complement(248494..249531)
/locus_tag="YGL138C"
/product="hypothetical protein"
/transcript_id="NM_001181003.1"
/db_xref="GI:296144912"
/db_xref="GeneID:852739"
CDS complement(248494..249531)
/locus_tag="YGL138C"
/note="hypothetical protein; has no significant sequence
similarity to any known protein"
/codon_start=1
/product="hypothetical protein"
/protein_id="NP_011377.1"
/db_xref="GI:6321300"
/db_xref="SGD:S000003106"
/db_xref="GeneID:852739"
/translation="MYNFLEFFFFFITYTLFKSTFVQGKSSFPGHDVCKFEDQNFQTE
FFLNVLKGDKLQNLKQEYEQYKKQSTLYTGFVIEKQYEYQVAPLQINNFLQVTFCKGG
KPIWNHILPFQKDLDWAEPLCIPAQEDDTISQNSSVCFKFARVQKYTQRNVTLYFPNK
FVGFVFVCNSSKTHPPTQNNFETIPLTPIISDDIRDYKISWSIKGRITKVVPYLHSLS
IPMSKYEMLIHSDKNISNELEYKSLTSEFWKSYKNLRKFKNKEMSWINEINPMEQYDS
SGNENVPNFHEKLDRTINRIAQNIERPHDALIRAIAAHNRNSNSGNITRRKYLRRKIS
KMLKNKIPLKN"
gene 249869..252738
/gene="SEC27"
/locus_tag="YGL137W"
/db_xref="GeneID:852740"
mRNA join(249869..249886,250087..252738)
/gene="SEC27"
/locus_tag="YGL137W"
/product="Sec27p"
/transcript_id="NM_001181002.1"
/db_xref="GI:296144913"
/db_xref="GeneID:852740"
CDS join(249869..249886,250087..252738)
/gene="SEC27"
/locus_tag="YGL137W"
/note="Essential beta'-coat protein of the COPI coatomer,
involved in ER-to-Golgi and Golgi-to-ER transport;
contains WD40 domains that mediate cargo selective
interactions; 45% sequence identity to mammalian
beta'-COP"
/codon_start=1
/product="Sec27p"
/protein_id="NP_011378.1"
/db_xref="GI:6321301"
/db_xref="SGD:S000003105"
/db_xref="GeneID:852740"
/translation="MKLDIKKTFSNRSDRVKGIDFHPTEPWVLTTLYSGRVELWNYET
QVEVRSIQVTETPVRAGKFIARKNWIIVGSDDFRIRVFNYNTGEKVVDFEAHPDYIRS
IAVHPTKPYVLSGSDDLTVKLWNWENNWALEQTFEGHEHFVMCVAFNPKDPSTFASGC
LDRTVKVWSLGQSTPNFTLTTGQERGVNYVDYYPLPDKPYMITASDDLTIKIWDYQTK
SCVATLEGHMSNVSFAVFHPTLPIIISGSEDGTLKIWNSSTYKVEKTLNVGLERSWCI
ATHPTGRKNYIASGFDNGFTVLSLGNDEPTLSLDPVGKLVWSGGKNAAASDIFTAVIR
GNEEVEQDEPLSLQTKELGSVDVFPQSLAHSPNGRFVTVVGDGEYVIYTALAWRNKAF
GKCQDFVWGPDSNSYALIDETGQIKYYKNFKEVTSWSVPMHSAIDRLFSGALLGVKSD
GFVYFFDWDNGTLVRRIDVNAKDVIWSDNGELVMIVNTNSNGDEASGYTLLFNKDAYL
EAANNGNIDDSEGVDEAFDVLYELSESITSGKWVGDVFIFTTATNRLNYFVGGKTYNL
AHYTKEMYLLGYLARDNKVYLADREVHVYGYEISLEVLEFQTLTLRGEIEEAIENVLP
NVEGKDSLTKIARFLEGQEYYEEALNISPDQDQKFELALKVGQLTLARDLLTDESAEM
KWRALGDASLQRFNFKLAVEAFTNAHDLESLFLLHSSFNNKEGLVTLAKDAERAGKFN
LAFNAYWIAGDIQGAKDLLIKSQRFSEAAFLGSTYGLGDDAVNDIVTKWKENLILNGK
NTVSERVCGAEGLPGSSSSGDAQPLIDLDSTPAPEQADENKEAEVEDSEFKESNSEAV
EAEKKEEEAPQQQQSEQQPEQGEAVPEPVEEES"
gene complement(252897..253859)
/gene="MRM2"
/locus_tag="YGL136C"
/db_xref="GeneID:852741"
mRNA complement(252897..253859)
/gene="MRM2"
/locus_tag="YGL136C"
/product="Mrm2p"
/transcript_id="NM_001181001.1"
/db_xref="GI:296144914"
/db_xref="GeneID:852741"
CDS complement(252897..253859)
/gene="MRM2"
/locus_tag="YGL136C"
/EC_number="2.1.1.-"
/note="Mitochondrial 2' O-ribose methyltransferase,
required for methylation of U(2791) in 21S rRNA; MRM2
deletion confers thermosensitive respiration and loss of
mitochondrial DNA; has similarity to Spb1p and Trm7p, and
to E. coli FtsJ/RrmJ"
/codon_start=1
/product="Mrm2p"
/protein_id="NP_011379.1"
/db_xref="GI:6321302"
/db_xref="SGD:S000003104"
/db_xref="GeneID:852741"
/translation="MILVYNRIRSIISSSLGRIHVRYNSNSQNRWLNRQLKDPYTKEA
KVQNLRSRAAFKLMQIDDKYRLFSKNRTDQRILDLGYAPGAWSQVARQRSSPNSMILG
VDILPCEPPHGVNSIQANILAKRTHDLIRLFFSKHFQLNRHDDLHKDHGYFQNMLEEE
LTHVKDTELYREIFTSDDIYETPNTNSTLIEREKFPVDVIISDMYEPWPQTTGFWNNI
TNQAYFRMANTSGVSIRDHYQSIDLCDAALVTAIDLLRPLGSFVCKLYTGEEENLFKK
RMQAVFTNVHKFKPDASRDESKETYYIGLKKKRNVDKLDVFSNS"
gene 254641..255294
/gene="RPL1B"
/locus_tag="YGL135W"
/gene_synonym="SSM2"
/db_xref="GeneID:852742"
mRNA 254641..255294
/gene="RPL1B"
/locus_tag="YGL135W"
/gene_synonym="SSM2"
/product="ribosomal 60S subunit protein L1B"
/transcript_id="NM_001181000.3"
/db_xref="GI:398364436"
/db_xref="GeneID:852742"
CDS 254641..255294
/gene="RPL1B"
/locus_tag="YGL135W"
/gene_synonym="SSM2"
/note="Ribosomal 60S subunit protein L1B; N-terminally
acetylated; homologous to mammalian ribosomal protein L10A
and bacterial L1; RPL1B has a paralog, RPL1A, that arose
from the whole genome duplication; rpl1a rpl1b double null
mutation is lethal"
/codon_start=1
/product="ribosomal 60S subunit protein L1B"
/protein_id="NP_011380.3"
/db_xref="GI:398364437"
/db_xref="SGD:S000003103"
/db_xref="GeneID:852742"
/translation="MSKITSSQVREHVKELLKYSNETKKRNFLETVELQVGLKNYDPQ
RDKRFSGSLKLPNCPRPNMSICIFGDAFDVDRAKSCGVDAMSVDDLKKLNKNKKLIKK
LSKKYNAFIASEVLIKQVPRLLGPQLSKAGKFPTPVSHNDDLYGKVTDVRSTIKFQLK
KVLCLAVAVGNVEMEEDVLVNQILMSVNFFVSLLKKNWQNVGSLVVKSSMGPAFRLY"
gene 255663..256964
/gene="PCL10"
/locus_tag="YGL134W"
/db_xref="GeneID:852743"
mRNA 255663..256964
/gene="PCL10"
/locus_tag="YGL134W"
/product="Pcl10p"
/transcript_id="NM_001180999.1"
/db_xref="GI:296144916"
/db_xref="GeneID:852743"
CDS 255663..256964
/gene="PCL10"
/locus_tag="YGL134W"
/note="Pho85p cyclin; recruits, activates, and targets
Pho85p cyclin-dependent protein kinase to its substrate"
/codon_start=1
/product="Pcl10p"
/protein_id="NP_011381.1"
/db_xref="GI:6321304"
/db_xref="SGD:S000003102"
/db_xref="GeneID:852743"
/translation="MDMTKNHTTDTEEFDDGDIRPVSLGIVDDYNASFELPLKPKFLQ
SENFSDLTSEWDQSRSNTPGLAEGKTEKAQPCGTTDSSKNRIHVEQLLESANEMNNYL
AQNIENINNFQVGLLNGGKGLYSSMGDDSSACINGTNFSSTSNFELSDDELEDTTGCT
SSIFDKDLFHQQNGLSIPRRRSPLFKSPTASFEIGDATDVEEQDIDDSIFSECSSITS
FDMGGLHISLPHDEEEDQEKTKSESENPLLHGIPVDVEVPHISVDEALANFKETIELL
LKLSGNRKCTGFNTRVEKKEYSNFYMKSKPTLSSADFLKRIQDKCEYQPTVYLVATFL
IDTLFLTRDGNNILQLKLNLQEKEVHRMIIAAVRLSTKLLEDFVHSHEYFSKVCGISK
RLLTKLEVSLLICVCNTKLMVSNRKLAASKLLLNELRSFCV"
gene 257707..261501
/gene="ITC1"
/locus_tag="YGL133W"
/db_xref="GeneID:852744"
mRNA 257707..261501
/gene="ITC1"
/locus_tag="YGL133W"
/product="Itc1p"
/transcript_id="NM_001180998.1"
/db_xref="GI:296144917"
/db_xref="GeneID:852744"
CDS 257707..261501
/gene="ITC1"
/locus_tag="YGL133W"
/note="Subunit of the ATP-dependent Isw2p-Itc1p chromatin
remodeling complex, required for repression of a-specific
genes, repression of early meiotic genes during mitotic
growth, and repression of INO1; similar to mammalian
Acf1p, the regulatory subunit of the mammalian
ATP-utilizing chromatin assembly and modifying factor
(ACF) complex"
/codon_start=1
/product="Itc1p"
/protein_id="NP_011382.1"
/db_xref="GI:6321305"
/db_xref="SGD:S000003101"
/db_xref="GeneID:852744"
/translation="MVLYKRKPILLPDPKPLPLDLNVQVWHIEETGEWFSSYEEFLER
FDFYTRHHFTCEITGTSCLTFFQALDSEETQFKYVEDRFPLKLREPVARFLHFNGIRR
LDALVEKVYARFKNDFFPGEVVYLRKQKDSSTTSSNSQQSTPQPDDMVEINSVGNPGL
PQYQYQRRYVIKEKVQFNATINPESREIVMPAHTKYMLIEEAASSNKSFIVDQGQIYR
DRSTFTKHLIKCFFKITLQRASSKMGAPWCVKPEYLAMYGLTMEWPKDMLKYKEDEPV
VARRSNSANVSSPESEKNKRQSKSSGKSNTSNDASNKKETKKKRKPTEVNDSENNSSE
EDKKKGQNVTSETHSKKRKKEANEEPNTENVESVPTPANAEPQAVTITSIMDDLALPY
QHPPNIFPNLTYYNEKLECISLGSTKLSRPFDSFGKLLQAYQFLNTFGSKICLSHFSL
DQFITSLKCTDPYELKGEVVLVNIRTQTSKEQEIENNGLPMKNKAETTTEEDSENPSD
WQRNSFIRDMIMKRNSDKVEYKIVHDDPASDDILDNINHNGSALLIEVFTALLRLFIN
EEGDWSCIVVENWIIDDKGVLMERKDERGEGEAKQKRNAHGYFLQDKEKIDNLKDTLK
ENATEVQKESDAKNETNSESDSKSDSDSEERDPKLEKCLNYRNVNWIERLTKRQFNNS
YWLIILLGVLEDCRHLPMYTEFIDSFIEKIIPKDISATQLPKQLWRNFCRKLSFSDKV
NALWILVDLVSHFSPDIKAAVDDSMELCGQIRSERFKVARELKTEAAVLSNLQGDLQA
IQEKLNKTDENTPSADGADKKDDSESNSEPIDLIIIEKKQKLIEEQDKKVQALQSDKN
FLDNCLFENDLQRLKPLGLDRYGNRYFWLDHNGVPFPQYPAGMNETPKSNNSLSYHSG
RLLIQGPKASSAKFFLNVSDEQLSNWQKIRNSEGISEATREVFGISKTSSGSYNYVEN
GIEVELLDSNDRVNPLIELTPIQKKIMDETPSRLLLSPDQWYCIDKLEDLSRIMDWLD
NWGRKEHDLLRQIRPIMERIKSSLSLRDHALSLTAFTKNEEKLLKELENNEFTENELN
VDSMDVDDKNSGVKSEVDVQVDAEEKREAVIDEKLEVIADELMKLDDSSKTRNVLNRI
QELEDQRDELLEQKKSIINSQRPGARILARSERKRTKISRGNKVNKQIEILTDLVNYR
HFKAMEDVIAWKNVLANSIWGSSLRKNASGNKRSGVIETVDDKLKDIVGQTSRTVTPA
PN"
gene complement(261648..265859)
/gene="SNT2"
/locus_tag="YGL131C"
/db_xref="GeneID:852746"
mRNA complement(261648..265859)
/gene="SNT2"
/locus_tag="YGL131C"
/product="Snt2p"
/transcript_id="NM_001180996.1"
/db_xref="GI:296144918"
/db_xref="GeneID:852746"
CDS complement(261648..265859)
/gene="SNT2"
/locus_tag="YGL131C"
/note="DNA binding protein with similarity to the S. pombe
Snt2 protein; RING finger ubiquitin ligase (E3) involved
in ubiquitylation and degradation of excess histones;
interacts with Ubc4p; null mutant sensitive to hydroxyurea
(HU); computational analysis suggests that Snt2p is a
transcription factor with a role in regulation of
expression of genes encoding amine transporters;
relocalizes from nucleus to cytoplasm upon DNA replication
stress"
/codon_start=1
/product="Snt2p"
/protein_id="NP_011384.1"
/db_xref="GI:6321307"
/db_xref="SGD:S000003099"
/db_xref="GeneID:852746"
/translation="MPKEEDFQLPRRREAAKNVNYNEMEIDTKLVQQIQIAEKSGAKT
KGSNSQTPRNCKRTSNPASRNEKFKYQKFLHDKNTCWNFIPTLPPSFRKNSRFSNILD
LDDAMIDLKKMSLFNTESVLLSANDTIYMISEPAGEPYYVGRVVNFVSKPEFSNTIHE
AIKTTSVFPAKFFQVRMNWFYRPRDIQEHVNTFNPRLVYASLHQDICPISSYRGKCSI
FHKDEVFDVLPNEKECIIRPNIFYFDELFDRYTLKYYKVYSTDKILNKWNSKSPFLYV
LNRRFRYIYTEPKYPLENVLKKYVFHELEVNELSPADYQWDKRCQFCKEWCIQKESLS
CDECGVCAHLYCMDPPLDRKPNKDVVWTCFSCLQKQQGTKDSHVRFLEEQALELDFIR
SVRQKIEEISSKAIKENVGYNTENCWFQYLGIYSISHIGDALNDSMFFPYPFKPSRVG
VKYQWNGCNHNVPWRRNSYISANSEEERGSTKTSELAWVLDASKITTRKLSEYIEQCK
SEICPILNVRGETCNFIDVVLKNLLFTNYDTAEAFKKCKRELSRKFLKEPSFTAVEIR
KFEEAVEKFGSELRPVCEYVGTQPMSMIVRFYYNWKKTERGLTVRGKLSKLSKNKRKK
EIANHENDVETKYIDDSSFDTEKLSLAESSFQCMFCKTDYSPMWYRVTGGSDDEKIKI
RMQTGVNEKTEISEKSPAHSKKNEKLGALCIRCARMWRRYAIKWVPPLETLRKITGTC
QNSFYSAIEGIIEENNTNKFTLSPFQAHNKLLEWELVQDSELIIRQRMKVYKNPNSFV
KMKRYSMTFHTQLYKMAVRSYRKNEFHPETMQRDLELFIEDNKEVRKAIPEQKPERAK
NTKDEFPVNIIRQSPGTIKTSDTSRNRKCNDVFIEKASNNNIPKITNASNDLIEISIK
TGGSSSGSVSVDKGFKFVKFDNKTFQRLRNSLKLVNNKLPKYNEPSTKKIKMINDIAL
SNPLNEPNGASYNYTVISHSKETSVALEKYHDGNKPSKMLEKDMILKHTKNKPKNPDT
AWANNSARTFCSVCKEKFNDNDNYEVVCGNCGLTVHYFCYAIKLPKDMKKNTNLKTFK
WLCDPCSNDLNPIISTTYQCSMCPTKDYDYDRYRSQSFKICPDALKCTSLGTWVHLVC
SLFNEDIKYGNGQSMQPALNTTAVLIKHSRFTCGVCRINGGGLVKCNKCQYRYHITCA
QNSSNFKLMFEKKNMSVDTTLPCIKDVKLNDTYTLRPILICDRHDISLEGNELYPLSY
KPQHTLSYIEQYCRYYKCESDHSLVELRYFEQLRLRHGEMPGNSHDSAIKPKIYVLPF
ERTCPHCGTNKSLYWYEDIICHSCNLRSGAQELDFDSASANISNDNGLPVEITQQLME
GIEPAMFDIDISEAGTDKNTHPSSQ"
gene 266145..267524
/gene="CEG1"
/locus_tag="YGL130W"
/db_xref="GeneID:852747"
mRNA 266145..267524
/gene="CEG1"
/locus_tag="YGL130W"
/product="Ceg1p"
/transcript_id="NM_001180995.3"
/db_xref="GI:398364448"
/db_xref="GeneID:852747"
CDS 266145..267524
/gene="CEG1"
/locus_tag="YGL130W"
/EC_number="2.7.7.50"
/note="Alpha (guanylyltransferase) subunit of the mRNA
capping enzyme, a heterodimer (the other subunit is CET1,
an RNA 5'-triphosphatase) involved in adding the 5' cap to
mRNA; the mammalian enzyme is a single bifunctional
polypeptide"
/codon_start=1
/product="Ceg1p"
/protein_id="NP_011385.3"
/db_xref="GI:398364449"
/db_xref="SGD:S000003098"
/db_xref="GeneID:852747"
/translation="MVLAMESRVAPEIPGLIQPGNVTQDLKMMVCKLLNSPKPTKTFP
GSQPVSFQHSDVEEKLLAHDYYVCEKTDGLRVLMFIVINPVTGEQGCFMIDRENNYYL
VNGFRFPRLPQKKKEELLETLQDGTLLDGELVIQTNPMTKLQELRYLMFDCLAINGRC
LTQSPTSSRLAHLGKEFFKPYFDLRAAYPNRCTTFPFKISMKHMDFSYQLVKVAKSLD
KLPHLSDGLIFTPVKAPYTAGGKDSLLLKWKPEQENTVDFKLILDIPMVEDPSLPKDD
RNRWYYNYDVKPVFSLYVWQGGADVNSRLKHFDQPFDRKEFEILERTYRKFAELSVSD
EEWQNLKNLEQPLNGRIVECAKNQETGAWEMLRFRDDKLNGNHTSVVQKVLESINDSV
SLEDLEEIVGDIKRCWDERRANMAGGSGRPLPSQSQNATLSTSKPVHSQPPSNDKEPK
YVDEDDWSD"
gene complement(267723..269075)
/gene="RSM23"
/locus_tag="YGL129C"
/db_xref="GeneID:852748"
mRNA complement(267723..269075)
/gene="RSM23"
/locus_tag="YGL129C"
/product="mitochondrial 37S ribosomal protein RSM23"
/transcript_id="NM_001180994.2"
/db_xref="GI:330443548"
/db_xref="GeneID:852748"
CDS complement(267723..269075)
/gene="RSM23"
/locus_tag="YGL129C"
/note="Mitochondrial ribosomal protein of the small
subunit, has similarity to mammalian apoptosis mediator
proteins; null mutation prevents induction of apoptosis by
overproduction of metacaspase Mca1p"
/codon_start=1
/product="mitochondrial 37S ribosomal protein RSM23"
/protein_id="NP_011386.2"
/db_xref="GI:330443549"
/db_xref="SGD:S000003097"
/db_xref="GeneID:852748"
/translation="MLRMSTSRFIGQRLFTTARSLQAAKPAPKGKTQGFSKKSSSVSS
YSSAKRVTPGSLYKNWTNTTHTAQLQQTAVPLALPIFNFDDISKTLNKVVSYSNKQYK
SLHHLGSFKKSQFNELFQKPVCLVREDATNSFLKKLVSHPVKKFIITGEPGVGKTVLL
SQAHAYAVDSKQIIINISYPELFLNGRNDFSYDDDLKLFIQPMYLKKLIRKILKANDP
ALLKSIELSKDYKFSNANPKNASVKPFVTLNKTKNTVLDLLSVMTHPHNRGKLMKAII
DELSVQSKVPIMFTVDNFSKVLTTAYSAYRNTENKQIYSLDLQMGKLMMDIISGETKF
ANGESSTILAISGVDRTNKTLPVALGKIPVDPYVTRYHYEPKFVELLQKGNVTEFEVP
KLNKQEVNELIDYYKQSNVLLDKDITGKKWENLIDEKYFLSGNGNPRELLKSLVLSHR
"
gene complement(269293..270144)
/gene="CWC23"
/locus_tag="YGL128C"
/db_xref="GeneID:852749"
mRNA complement(269293..270144)
/gene="CWC23"
/locus_tag="YGL128C"
/product="Cwc23p"
/transcript_id="NM_001180993.1"
/db_xref="GI:296144921"
/db_xref="GeneID:852749"
CDS complement(269293..270144)
/gene="CWC23"
/locus_tag="YGL128C"
/note="Component of a complex containing Cef1p, putatively
involved in pre-mRNA splicing; has similarity to E. coli
DnaJ and other DnaJ-like proteins and to S. pombe Cwf23p"
/codon_start=1
/product="Cwc23p"
/protein_id="NP_011387.2"
/db_xref="GI:37362651"
/db_xref="SGD:S000003096"
/db_xref="GeneID:852749"
/translation="MPGHELEDVINQRLNLYDVLELPTPLDVHTIYDDLPQIKRKYRT
LALKYHPDKHPDNPSIIHKFHLLSTATNILTNADVRPHYDRWLIEFLRKTNDIERNKL
IQKLEESESSTIPTTTPHPDLLQIQRHGELLRKLKHFNLPYGDWKHLNTQDQENASQH
PYYDCSTLRIVLDNFLQSNNKSNCLSHLRNQVFITLSANEIYDIYFSERNNYSKDDSI
IIYTVFDTPITAQHVFRNWSSGNLIPTVKDISPLIPLHYYSDFNLETELNDDIARLVS
NEPILLD"
gene complement(270392..270775)
/gene="SOH1"
/locus_tag="YGL127C"
/gene_synonym="MED31"
/db_xref="GeneID:852750"
mRNA complement(270392..270775)
/gene="SOH1"
/locus_tag="YGL127C"
/gene_synonym="MED31"
/product="Soh1p"
/transcript_id="NM_001180992.1"
/db_xref="GI:296144922"
/db_xref="GeneID:852750"
CDS complement(270392..270775)
/gene="SOH1"
/locus_tag="YGL127C"
/gene_synonym="MED31"
/note="Subunit of the RNA polymerase II mediator complex;
associates with core polymerase subunits to form the RNA
polymerase II holoenzyme; involved in telomere
maintenance; conserved with other metazoan MED31 subunits"
/codon_start=1
/product="Soh1p"
/protein_id="NP_011388.1"
/db_xref="GI:6321311"
/db_xref="SGD:S000003095"
/db_xref="GeneID:852750"
/translation="MSSTNGNAPATPSSDQNPLPTRFEVELEFIQSLANIQYVTYLLT
QQQIWKSPNFKNYLKYLEYWCNPPYSQCIVYPNCLFILKLLNGFMESAIVNEDGLLEG
LDELPKIIQLQGPQWMNEMVERWAN"
gene 270997..272139
/gene="SCS3"
/locus_tag="YGL126W"
/gene_synonym="FIT2B"
/db_xref="GeneID:852751"
mRNA 270997..272139
/gene="SCS3"
/locus_tag="YGL126W"
/gene_synonym="FIT2B"
/product="Scs3p"
/transcript_id="NM_001180991.3"
/db_xref="GI:398364458"
/db_xref="GeneID:852751"
CDS 270997..272139
/gene="SCS3"
/locus_tag="YGL126W"
/gene_synonym="FIT2B"
/note="Protein required for inositol prototrophy,
identified as an ortholog of the FIT family of proteins
involved in triglyceride droplet biosynthesis; disputed
role in the synthesis of inositol phospholipids from
inositol"
/codon_start=1
/product="Scs3p"
/protein_id="NP_011389.3"
/db_xref="GI:398364459"
/db_xref="SGD:S000003094"
/db_xref="GeneID:852751"
/translation="MSSKWFNAIHLLVCPLTVLVGYLMNAYGYGAALQATLNKDGLVN
AMLVKKGWFWTSLVGWWCIIRYRAVPGATGRDRRHIVQSFKRYAILTVWWYVFTQGIW
FGVGPIMDLVFVYTGGHCHYDVFDDAGHVNEDFQGSVTRTNRALALIHNVLTLHGHHQ
EHRQQQLWDRSIGSIQGALQATQPKTPKNVTASAAAAINTFIHDQMHRWQGPLTTSAQ
CRRFGGHWAGGHDPSGHVFLATLMCMFLLGELRVFGRRALAHLYAQKWQLVRLVTRLF
DTGPLWTWRRCGGGSMTCGARLWRAIVEPPVTCAAALLRLTRCIACDHPVIILLTLLV
TWLWQLLLTAVASRFHTVREHMSGLLAAYIVTGLVYARDAAALRPV"
gene 272520..274322
/gene="MET13"
/locus_tag="YGL125W"
/gene_synonym="MET11; MRPL45"
/db_xref="GeneID:852752"
mRNA 272520..274322
/gene="MET13"
/locus_tag="YGL125W"
/gene_synonym="MET11; MRPL45"
/product="methylenetetrahydrofolate reductase (NAD(P)H)
MET13"
/transcript_id="NM_001180990.1"
/db_xref="GI:296144924"
/db_xref="GeneID:852752"
CDS 272520..274322
/gene="MET13"
/locus_tag="YGL125W"
/gene_synonym="MET11; MRPL45"
/EC_number="1.5.1.20"
/note="Major isozyme of methylenetetrahydrofolate
reductase, catalyzes the reduction of
5,10-methylenetetrahydrofolate to 5-methyltetrahydrofolate
in the methionine biosynthesis pathway"
/codon_start=1
/product="methylenetetrahydrofolate reductase (NAD(P)H)
MET13"
/protein_id="NP_011390.2"
/db_xref="GI:27808705"
/db_xref="SGD:S000003093"
/db_xref="GeneID:852752"
/translation="MKITEKLEQHRQTSGKPTYSFEYFVPKTTQGVQNLYDRMDRMYE
ASLPQFIDITWNAGGGRLSHLSTDLVATAQSVLGLETCMHLTCTNMPISMIDDALENA
YHSGCQNILALRGDPPRDAENWTPVEGGFQYAKDLIKYIKSKYGDHFAIGVAGYPECH
PELPNKDVKLDLEYLKQKIDAGGDFIITQMFYDVDNFINWCSQVRAAGMDVPIIPGIM
PITTYAAFLRRAQWGQISIPQHFSSRLDPIKDDDELVRDIGTNLIVEMCQKLLDSGYV
SHLHIYTMNLEKAPLMILERLNILPTESEFNAHPLAVLPWRKSLNPKRKNEEVRPIFW
KRRPYSYVARTSQWAVDEFPNGRFGDSSSPAFGDLDLCGSDLIRQSANKCLELWSTPT
SINDVAFLVINYLNGNLKCLPWSDIPINDEINPIKAHLIELNQHSIITINSQPQVNGI
RSNDKIHGWGPKDGYVYQKQYLEFMLPKTKLPKLIDTLKNNEFLTYFAIDSQGDLLSN
HPDNSKSNAVTWGIFPGREILQPTIVEKISFLAWKEEFYHILNEWKLNMNKYDKPHSA
QFIQSLIDDYCLVNIVDNDYISPDDQIHSILLSL"
gene complement(274780..276714)
/gene="MON1"
/locus_tag="YGL124C"
/gene_synonym="AUT12"
/db_xref="GeneID:852753"
mRNA complement(274780..276714)
/gene="MON1"
/locus_tag="YGL124C"
/gene_synonym="AUT12"
/product="Mon1p"
/transcript_id="NM_001180989.2"
/db_xref="GI:330443550"
/db_xref="GeneID:852753"
CDS complement(274780..276714)
/gene="MON1"
/locus_tag="YGL124C"
/gene_synonym="AUT12"
/note="Protein required for fusion of cvt-vesicles and
autophagosomes with the vacuole; associates, as a complex
with Ccz1p, with a perivacuolar compartment; potential
Cdc28p substrate"
/codon_start=1
/product="Mon1p"
/protein_id="NP_011391.2"
/db_xref="GI:330443551"
/db_xref="SGD:S000003092"
/db_xref="GeneID:852753"
/translation="MNLNESYLDAEIPKGQLKHSKSGNFEGIPIVATTSEPTTSVNLD
ETFFKKAPIAMPICDDHSVSKSTSVNSLNTTSLASRRSPLQTKKLQAKNNLLSADLAK
SNDDTTRALNSPKKDFGPYLDSENDIRSRLAESIYSMETSIRGSELQRRPYVSNEIPN
VFKFSKFNSNCKLNESQTLCDKNFFIFTSAGKPIYCMHGKDEQIMSYTGLVNTVISYF
QVNGPSELKTISTLTSGKRLTFLDKSPILLMAQSERGESSNELLNQLDFLYSYILSSL
SERQLLRLFSKRENFDLRNYLESTDFENLDEICSLICNRMFPDLLLNSLQCLPFNHSS
RLKLQNVVLQQLEKRQDIPRGTLLYGLIIAPQNKLCCVLRPRGHTLHTTDLHLLFCLI
SHQFQNLDETQELWVPICFPKFNSSGFLYCYIKFLPNDTHSNEKSALVLISAQKDAFF
SLKSFSDELIIKLEEEKLLKKINTSKGFKLSDIPAPMVHHFIYKSKQNVQYVMPHFEV
NSNIALDSSQGLEYELKLKTYYQQLHGTVVRDNGNLLSRSMLNFVRWSSKDNEDLAMD
ETQMDFSELDEYIIGNSSFKQESVNMVGMAWVTPTFELYLIGNNGIVDKRVLFKSARK
VANWCQKHESRLFISDGAVF"
gene 277617..278381
/gene="RPS2"
/locus_tag="YGL123W"
/gene_synonym="RPS4; SUP138; SUP38; SUP44"
/db_xref="GeneID:852754"
mRNA 277617..278381
/gene="RPS2"
/locus_tag="YGL123W"
/gene_synonym="RPS4; SUP138; SUP38; SUP44"
/product="ribosomal 40S subunit protein S2"
/transcript_id="NM_001180988.1"
/db_xref="GI:296144926"
/db_xref="GeneID:852754"
CDS 277617..278381
/gene="RPS2"
/locus_tag="YGL123W"
/gene_synonym="RPS4; SUP138; SUP38; SUP44"
/note="Protein component of the small (40S) subunit;
essential for control of translational accuracy;
phosphorylation by C-terminal domain kinase I (CTDK-I)
enhances translational accuracy; methylated on one or more
arginine residues by Hmt1p; homologous to mammalian
ribosomal protein S2 and bacterial S5"
/codon_start=1
/product="ribosomal 40S subunit protein S2"
/protein_id="NP_011392.1"
/db_xref="GI:6321315"
/db_xref="SGD:S000003091"
/db_xref="GeneID:852754"
/translation="MSAPEAQQQKRGGFGGRNRGRPNRRGPRNTEEKGWVPVTKLGRL
VKAGKITTIEEIFLHSLPVKEFQIIDTLLPGLQDEVMNIKPVQKQTRAGQRTRFKAVV
VVGDSNGHVGLGIKTAKEVAGAIRAGIIIAKLSVIPIRRGYWGTNLGQPHSLATKTTG
KCGSVTVRLIPAPRGSGIVASPAVKKLLQLAGVEDVYTQSNGKTRTLENTLKAAFVAI
GNTYGFLTPNLWAEQPLPVSPLDIYSDEASAQKKRF"
gene complement(278946..280523)
/gene="NAB2"
/locus_tag="YGL122C"
/db_xref="GeneID:852755"
mRNA complement(278946..280523)
/gene="NAB2"
/locus_tag="YGL122C"
/product="Nab2p"
/transcript_id="NM_001180987.3"
/db_xref="GI:398364466"
/db_xref="GeneID:852755"
CDS complement(278946..280523)
/gene="NAB2"
/locus_tag="YGL122C"
/note="Nuclear polyadenylated RNA-binding protein;
required for nuclear mRNA export and poly(A) tail length
control; binds nuclear pore protein Mlp1p; autoregulates
mRNA levels; related to human hnRNPs; nuclear localization
sequence binds Kap104p; protein abundance increases in
response to DNA replication stress"
/codon_start=1
/product="Nab2p"
/protein_id="NP_011393.3"
/db_xref="GI:398364467"
/db_xref="SGD:S000003090"
/db_xref="GeneID:852755"
/translation="MSQEQYTENLKVIVAEKLAGIPNFNEDIKYVAEYIVLLIVNGGT
VESVVDELASLFDSVSRDTLANVVQTAFFALEALQQGESAENIVSKIRMMNAQSLGQS
DIAQQQQQQQQQQQPDIAQQQPQQQPQQQPQQQPQQQPQQQPQQQPQQQPQQQPQLQP
LQPQLGTQNAMQTDAPATPSPISAFSGVVNAAAPPQFAPVDNSQRFTQRGGGAVGKNR
RGGRGGNRGGRNNNSTRFNPLAKALGMAGESNMNFTPTKKEGRCRLFPHCPLGRSCPH
AHPTKVCNEYPNCPKPPGTCEFLHPNEDEELMKEMERTREEFQKRKADLLAAKRKPVQ
TGIVLCKFGALCSNPSCPFGHPTPANEDAKVIDLMWCDKNLTCDNPECRKAHSSLSKI
KEVKPISQKKAAPPPVEKSLEQCKFGTHCTNKRCKYRHARSHIMCREGANCTRIDCLF
GHPINEDCRFGVNCKNIYCLFRHPPGRVLPEKKGAAPNSNVPTNERPFALPENAIIEN
APPQTSFTHQEQDTEMN"
gene complement(280777..281157)
/gene="GPG1"
/locus_tag="YGL121C"
/db_xref="GeneID:852756"
mRNA complement(280777..281157)
/gene="GPG1"
/locus_tag="YGL121C"
/product="Gpg1p"
/transcript_id="NM_001180986.1"
/db_xref="GI:296144928"
/db_xref="GeneID:852756"
CDS complement(280777..281157)
/gene="GPG1"
/locus_tag="YGL121C"
/note="Proposed gamma subunit of the heterotrimeric G
protein that interacts with the receptor Gpr1p; involved
in regulation of pseudohyphal growth; requires Gpb1p or
Gpb2p to interact with Gpa2p; overproduction causes prion
curing"
/codon_start=1
/product="Gpg1p"
/protein_id="NP_011394.1"
/db_xref="GI:6321317"
/db_xref="SGD:S000003089"
/db_xref="GeneID:852756"
/translation="MFYLSDIEEEASAGAEPTYNFWEVLLFSNTQENLVTVVGELHTL
TDRVVHYKIEPESREVTATTLPSLLALLLEKRNQARRLYRDVLSMKMSELDWDIDDLF
TQLQEELTRTDDTLSMYPRRRFYH"
gene complement(281634..283937)
/gene="PRP43"
/locus_tag="YGL120C"
/db_xref="GeneID:852757"
mRNA complement(281634..283937)
/gene="PRP43"
/locus_tag="YGL120C"
/product="Prp43p"
/transcript_id="NM_001180985.1"
/db_xref="GI:296144929"
/db_xref="GeneID:852757"
CDS complement(281634..283937)
/gene="PRP43"
/locus_tag="YGL120C"
/EC_number="3.6.1.-"
/note="RNA helicase in the DEAH-box family, functions in
both RNA polymerase I and polymerase II transcript
metabolism, involved in release of the lariat-intron from
the spliceosome"
/codon_start=1
/product="Prp43p"
/protein_id="NP_011395.1"
/db_xref="GI:6321318"
/db_xref="SGD:S000003088"
/db_xref="GeneID:852757"
/translation="MGSKRRFSSEHPDPVETSIPEQAAEIAEELSKQHPLPSEEPLVH
HDAGEFKGLQRHHTSAEEAQKLEDGKINPFTGREFTPKYVDILKIRRELPVHAQRDEF
LKLYQNNQIMVFVGETGSGKTTQIPQFVLFDEMPHLENTQVACTQPRRVAAMSVAQRV
AEEMDVKLGEEVGYSIRFENKTSNKTILKYMTDGMLLREAMEDHDLSRYSCIILDEAH
ERTLATDILMGLLKQVVKRRPDLKIIIMSATLDAEKFQRYFNDAPLLAVPGRTYPVEL
YYTPEFQRDYLDSAIRTVLQIHATEEAGDILLFLTGEDEIEDAVRKISLEGDQLVREE
GCGPLSVYPLYGSLPPHQQQRIFEPAPESHNGRPGRKVVISTNIAETSLTIDGIVYVV
DPGFSKQKVYNPRIRVESLLVSPISKASAQQRAGRAGRTRPGKCFRLYTEEAFQKELI
EQSYPEILRSNLSSTVLELKKLGIDDLVHFDFMDPPAPETMMRALEELNYLACLDDEG
NLTPLGRLASQFPLDPMLAVMLIGSFEFQCSQEILTIVAMLSVPNVFIRPTKDKKRAD
DAKNIFAHPDGDHITLLNVYHAFKSDEAYEYGIHKWCRDHYLNYRSLSAADNIRSQLE
RLMNRYNLELNTTDYESPKYFDNIRKALASGFFMQVAKKRSGAKGYITVKDNQDVLIH
PSTVLGHDAEWVIYNEFVLTSKNYIRTVTSVRPEWLIEIAPAYYDLSNFQKGDVKLSL
ERIKEKVDRLNELKQGKNKKKSKHSKK"
gene 284442..285947
/gene="COQ8"
/locus_tag="YGL119W"
/gene_synonym="ABC1"
/db_xref="GeneID:852758"
mRNA 284442..285947
/gene="COQ8"
/locus_tag="YGL119W"
/gene_synonym="ABC1"
/product="Coq8p"
/transcript_id="NM_001180984.1"
/db_xref="GI:296144930"
/db_xref="GeneID:852758"
CDS 284442..285947
/gene="COQ8"
/locus_tag="YGL119W"
/gene_synonym="ABC1"
/note="Protein required for ubiquinone biosynthesis and
respiratory growth; exhibits genetic interaction with
COQ9, suggesting a common function; similar to prokaryotic
proteins involved in early steps of ubiquinone
biosynthesis; COQ8 has a paralog, YBR230W-A, that arose
from the whole genome duplication"
/codon_start=1
/product="Coq8p"
/protein_id="NP_011396.1"
/db_xref="GI:6321319"
/db_xref="SGD:S000003087"
/db_xref="GeneID:852758"
/translation="MVTNMVKLRNLRRLYCSSRLLRTIQNGRISSVSSISLSKKYTTK
SAKEGEENVERKHEEEKKDTLKSSSVPTSRISRLFHYGSLAAGVGMNAAAKGISEVAK
GNSPTWKSLILSDSNIDRITNKFSKMRGVALKIGQLLSFQDEKVLPKELYEILSRVQN
SANHMPQRQLEKVMAKELGANWKTKFSKFDKIPMAAASIGQVHAAELPSGQRVVVKIQ
YPGVKESIDSDLNSLLMLLTASSLLPKGLFLDKTIANARTELKWECDYNREARALQKF
EALLKDDPAFEVPHVFPEYTTDNIITMTRMEGTEIMKLPKASQETKNFISENIMRLCL
EEIATFKYMQTDPNWANFLYNGRTKKIELLDFGASRPFAEDFILKYRKLLTYATLRDR
KGAYEMSVQLGYLTGLESQSMKDAHVDSVLTLGEPFRGDVDKSFDFKDQTVSDRIRGN
IGLMLNERLCPPPEETYSLHRKFSGIFLLCARMGASVHCAKLFKEIFAYKV"
rep_origin 285948..286242
/note="ARS714;
Autonomously Replicating Sequence"
/db_xref="SGD:S000118455"
gene complement(287350..287455)
/locus_tag="tW(CCA)G1"
/db_xref="GeneID:852759"
tRNA complement(join(287350..287385,287420..287455))
/locus_tag="tW(CCA)G1"
/product="tRNA-Trp"
/note="Tryptophan tRNA (tRNA-Trp), predicted by
tRNAscan-SE analysis"
/db_xref="SGD:S000006771"
/db_xref="GeneID:852759"
rep_origin 288451..288512
/note="ARS715;
Putative replication origin, identified in multiple array
studies, not yet confirmed by plasmid-based assay"
/db_xref="SGD:S000130165"
gene 288512..289309
/locus_tag="YGL117W"
/db_xref="GeneID:852761"
mRNA 288512..289309
/locus_tag="YGL117W"
/product="hypothetical protein"
/transcript_id="NM_001180982.3"
/db_xref="GI:398364476"
/db_xref="GeneID:852761"
CDS 288512..289309
/locus_tag="YGL117W"
/codon_start=1
/product="hypothetical protein"
/protein_id="NP_011398.3"
/db_xref="GI:398364477"
/db_xref="SGD:S000003085"
/db_xref="GeneID:852761"
/translation="MQPISIKDVESDQGKVYIVNALKDLVCKCLLEFVDIQIESFMYP
DDPKCFTRIFKGNKIVNEASDKDSKVRSYPSSLGVGHSALFPLIYIRQKTNSLRFLND
PKQLPTPLVDDMNAKFKGIIKVYENLIHLYHSYQTVDCNNMNQQKLLGDLVSRGNFML
DILHGYVTIASTIVRDSKDANILIDTVNRFIHDTILFHKRIIHNSNAYTEYHVMKRGM
QRNQSEETLVELEFRILDVSDVNLDNEFDDFLQHRKTSLKITHRRVI"
gene 289809..291641
/gene="CDC20"
/locus_tag="YGL116W"
/gene_synonym="PAC5"
/db_xref="GeneID:852762"
mRNA 289809..291641
/gene="CDC20"
/locus_tag="YGL116W"
/gene_synonym="PAC5"
/product="Cdc20p"
/transcript_id="NM_001180981.1"
/db_xref="GI:296144932"
/db_xref="GeneID:852762"
CDS 289809..291641
/gene="CDC20"
/locus_tag="YGL116W"
/gene_synonym="PAC5"
/note="Activator of anaphase-promoting complex/cyclosome
(APC/C); APC/C is required for metaphase/anaphase
transition; directs ubiquitination of mitotic cyclins,
Pds1p, and other anaphase inhibitors; cell-cycle
regulated; potential Cdc28p substrate; relative
distribution to the nucleus increases upon DNA replication
stress"
/codon_start=1
/product="Cdc20p"
/protein_id="NP_011399.1"
/db_xref="GI:6321322"
/db_xref="SGD:S000003084"
/db_xref="GeneID:852762"
/translation="MPESSRDKGNAAISGNRSVLSIASPTKLNILSSDWSRNQGKVSK
NSLKRSSSLNIRNSKRPSLQASANSIYSRPKITIGAPPLIRRDSSFFKDEFDAKKDKA
TFSAYSSRSYPTIGSESVVSQTSLSQPTTSREVDEQFTVAADRYIPILQGASQNKVDP
ETLHEALPPPNASPISHLRAQTKIVFKQNVAEACGLDMNKRILQYMPEPPKCSSLRQK
SYIMKKRTHYSYQQEQKIPDLIKLRKINTNPERILDAPGFQDDFYLNLLSWSKKNVLA
IALDTALYLWNATTGDVSLLTDFENTTICSVTWSDDDCHISIGKEDGNTEIWDVETMS
LIRTMRSGLGVRIGSLSWLDTLIATGSRSGEIQINDVRIKQHIVSTWAEHTGEVCGLS
YKSDGLQLASGGNDNTVMIWDTRTSLPQFSKKTHTAAVKALSWCPYSPNILASGGGQT
DKHIHFWNSITGARVGSINTGSQVSSLHWGQSHTSTNGGMMNKEIVATGGNPENAISV
YNYETKFKVAEVVHAHEARICCSQLSPDGTTLATVGGDENLKFYKIFDPRCTGRSRED
GLMDGMLGLIGKEGCRTNDKENRSKNSSEIHTRRPSSTSQYLIR"
gene 292033..293001
/gene="SNF4"
/locus_tag="YGL115W"
/gene_synonym="CAT3; SCI1"
/db_xref="GeneID:852763"
mRNA 292033..293001
/gene="SNF4"
/locus_tag="YGL115W"
/gene_synonym="CAT3; SCI1"
/product="Snf4p"
/transcript_id="NM_001180980.1"
/db_xref="GI:296144933"
/db_xref="GeneID:852763"
CDS 292033..293001
/gene="SNF4"
/locus_tag="YGL115W"
/gene_synonym="CAT3; SCI1"
/note="Activating gamma subunit of the AMP-activated Snf1p
kinase complex; additional subunits of the complex are
Snf1p and a Sip1p/Sip2p/Gal83p family member; activates
glucose-repressed genes, represses glucose-induced genes;
role in sporulation, and peroxisome biogenesis; protein
abundance increases in response to DNA replication stress"
/codon_start=1
/product="Snf4p"
/protein_id="NP_011400.1"
/db_xref="GI:6321323"
/db_xref="SGD:S000003083"
/db_xref="GeneID:852763"
/translation="MKPTQDSQEKVSIEQQLAVESIRKFLNSKTSYDVLPVSYRLIVL
DTSLLVKKSLNVLLQNSIVSAPLWDSKTSRFAGLLTTTDFINVIQYYFSNPDKFELVD
KLQLDGLKDIERALGVDQLDTASIHPSRPLFEACLKMLESRSGRIPLIDQDEETHREI
VVSVLTQYRILKFVALNCRETHFLKIPIGDLNIITQDNMKSCQMTTPVIDVIQMLTQG
RVSSVPIIDENGYLINVYEAYDVLGLIKGGIYNDLSLSVGEALMRRSDDFEGVYTCTK
NDKLSTIMDNIRKARVHRFFVVDDVGRLVGVLTLSDILKYILLGSN"
gene 293460..295637
/locus_tag="YGL114W"
/db_xref="GeneID:852764"
mRNA 293460..295637
/locus_tag="YGL114W"
/product="hypothetical protein"
/transcript_id="NM_001180979.1"
/db_xref="GI:296144934"
/db_xref="GeneID:852764"
CDS 293460..295637
/locus_tag="YGL114W"
/note="hypothetical protein; predicted member of the
oligopeptide transporter (OPT) family of membrane
transporters"
/codon_start=1
/product="hypothetical protein"
/protein_id="NP_011401.1"
/db_xref="GI:6321324"
/db_xref="SGD:S000003082"
/db_xref="GeneID:852764"
/translation="MPQSTPSQEVQRVPWDNKPALKQITLRATIAGIAIGSLVLTSNF
QFGLQTGWVSMMSLPSALLACAFFKNIWPLIFPNDRPFSDVENVYVQSMAVAVGTGPL
AFGFVGVIPAIEKFLTNDESGGLREQGQSFTFRELLIWSTALAFFGIFFAVPLRKQVI
VREKLPFPSGSATATLISVLNGTEILQEVSKSELLEMRQRRLNECPEVLQPNRDPEEA
DYLMNSSHSELGDYTATSQDGSSILSTGSENYRANIIILLKTFVVSSLYTMVSYFVPV
IRSIPVFGKYLSNNYLWNFQPSPAYIGQGIIMGLPTVSYMLIGCFLGWGVLAPLARYK
RWVPPDADVHDWEEGVQGWILWSSLSIMVADSVVAFIVVTVKSIVKFILIDDKAALLN
NIIDDTFQSMLLEEERAINSSRRNTYVDGRQDTVRLVSRDNEIEVDSKHLVRYTTVIS
GCLVSSIICIVSIIYLFGIQVIPLYAIITALILALFLSILGIRALGETDLNPVSGIGK
ISQLIFAFIIPRDRPGSVLMNVVSGGIAEASAQQAGDLMQDLKTGHLLGASPRAQFCA
QLIGACWSIILSSFMYLCYNKVYSIPSEQFRIPTAVVWIDCARLVTGKGLPDKALECS
MILGVIFAVLSLIRNTYRDYGYGWILYIPSGVAVGVGIFNSPSFTIARFIGGWASHFW
LKNHRGDLNAKTKMIVFSSGLVLGEGIFSVINMLFICLNVPHY"
gene 295932..297938
/gene="SLD3"
/locus_tag="YGL113W"
/db_xref="GeneID:852765"
mRNA 295932..297938
/gene="SLD3"
/locus_tag="YGL113W"
/product="Sld3p"
/transcript_id="NM_001180978.3"
/db_xref="GI:398364488"
/db_xref="GeneID:852765"
CDS 295932..297938
/gene="SLD3"
/locus_tag="YGL113W"
/note="Protein involved in the initiation of DNA
replication; required for proper assembly of replication
proteins at the origins of replication; interacts with
Cdc45p; localizes to nuclear foci that become diffuse upon
DNA replication stress"
/codon_start=1
/product="Sld3p"
/protein_id="NP_011402.3"
/db_xref="GI:398364489"
/db_xref="SGD:S000003081"
/db_xref="GeneID:852765"
/translation="METWEVIASVKEATKGLDLSLDHPLIIKSEDVPSNILQLLQQKN
RRQLKHICMKSRKEYFLLEEYGPGFWVKWPYNYFNGYSLPERRTEVVTTVERERAKRE
TLKTWDELKFKELLHLWSEEPKGSCKLEKDKDLKLDMNPPDMKGESKINDYYSDPKEY
IESKYYDALFSIHTPLAYFVKSNLVRLKNTCRTKYGSDSYKIAYQAMLQKFLLSIVQF
KDRHDNRLLLEPFSSPIADEKRKNCLTKFVIQDENKNSSTIADLCVVLKSREIKLQIL
LLLEIIGLNDLDWNFRDFEKKYKLKLKKRSLNLTKKGLVRRRSKKKTSEKDKGIERIT
TSLDYCEQLDLYLDRACILDILLSSETPNPDAIEASNGTIQEHKKNILDKSKEASLVG
FINYVLIPYFNKKVPHAVEFIIQKLKGPSMRPKRALKKVNDSTNVSSPNTVETYNRLS
TSQRASRSSIINSVPSSPALRRVDANLFSRKSIASPTPELLNSRTNSNLNEFLESETR
SLKRPSQLGRTKSDLTMNHLQKRQFSVSDLSTTRVPNSSTITLKTPFSHSTINAYKTM
NNSFRRVGKRKDINETIRLHERVDSEENVQVQATPAVKKRTVTPNKKAQLQSIIESPL
NFKDDDTHEGRKNTSNITSTPTNKPPENSSKRRVRRRLFAPEST"
gene complement(298178..299728)
/gene="TAF6"
/locus_tag="YGL112C"
/gene_synonym="TAF60"
/db_xref="GeneID:852766"
mRNA complement(298178..299728)
/gene="TAF6"
/locus_tag="YGL112C"
/gene_synonym="TAF60"
/product="Taf6p"
/transcript_id="NM_001180977.1"
/db_xref="GI:296144936"
/db_xref="GeneID:852766"
CDS complement(298178..299728)
/gene="TAF6"
/locus_tag="YGL112C"
/gene_synonym="TAF60"
/note="Subunit (60 kDa) of TFIID and SAGA complexes,
involved in transcription initiation of RNA polymerase II
and in chromatin modification, similar to histone H4"
/codon_start=1
/product="Taf6p"
/protein_id="NP_011403.1"
/db_xref="GI:6321326"
/db_xref="SGD:S000003080"
/db_xref="GeneID:852766"
/translation="MSTQQQSYTIWSPQDTVKDVAESLGLENINDDVLKALAMDVEYR
ILEIIEQAVKFKRHSKRDVLTTDDVSKALRVLNVEPLYGYYDGSEVNKAVSFSKVNTS
GGQSVYYLDEEEVDFDRLINEPLPQVPRLPTFTTHWLAVEGVQPAIIQNPNLNDIRVS
QPPFIRGAIVTALNDNSLQTPVTSTTASASVTDTGASQHLSNVKPGQNTEVKPLVKHV
LSKELQIYFNKVISTLTAKSQADEAAQHMKQAALTSLRTDSGLHQLVPYFIQFIAEQI
TQNLSDLQLLTTILEMIYSLLSNTSIFLDPYIHSLMPSILTLLLAKKLGGSPKDDSPQ
EIHEFLERTNALRDFAASLLDYVLKKFPQAYKSLKPRVTRTLLKTFLDINRVFGTYYG
CLKGVSVLEGESIRFFLGNLNNWARLVFNESGITLDNIEEHLNDDSNPTRTKFTKEET
QILVDTVISALLVLKKDLPDLYEGKGEKVTDEDKEKLLERCGVTIGFHILKRDDAKEL
ISAIFFGE"
gene 299978..301369
/gene="NSA1"
/locus_tag="YGL111W"
/db_xref="GeneID:852767"
mRNA 299978..301369
/gene="NSA1"
/locus_tag="YGL111W"
/product="Nsa1p"
/transcript_id="NM_001180976.1"
/db_xref="GI:296144937"
/db_xref="GeneID:852767"
CDS 299978..301369
/gene="NSA1"
/locus_tag="YGL111W"
/note="Constituent of 66S pre-ribosomal particles,
involved in 60S ribosomal subunit biogenesis"
/codon_start=1
/product="Nsa1p"
/protein_id="NP_011404.1"
/db_xref="GI:6321327"
/db_xref="SGD:S000003079"
/db_xref="GeneID:852767"
/translation="MRLLVSCVDSGSIKEVLCNIGTDTSVQSALQPFHVAPHLAEGLK
AYVDRMWVISEDEAILARNSGVVELVKISKHLKENEALQVDPKGESKNEKSLSDDLPK
FDISEFEITSSVSDLFDDAKLESLSSKSVKRTKLVDGFVTLCPIKKDSSNNTFVAATK
SGLLHIIKKGEDKKLIKLASLGLKAPVEFLQLYDLEDTDTDKYIFAYGGEENLIKLVE
IDSSFQSLKQIWEAKNVKNDRLDMRVPVWPMALRFLEPSPGKTEKGKLNYQFAAITRW
SHLTKYSTQHGRKPFAQIDLLPNREPLSQMEVFDAKGENVVSSLGNFQSETFNELNVI
TTDYKKNVFKFDGNGRMLGKVGRDDITGSSTYIHVHDGKYLLQGGLDRYVRIFDIKTN
KMLVKVYVGSRINFIVMLDDVEIEMPLSPSAKAAKGKQKRKVTELEEDADELWNKLEG
KVAASKASKKSKI"
gene complement(301537..303411)
/gene="CUE3"
/locus_tag="YGL110C"
/db_xref="GeneID:852768"
mRNA complement(301537..303411)
/gene="CUE3"
/locus_tag="YGL110C"
/product="Cue3p"
/transcript_id="NM_001180975.1"
/db_xref="GI:296144938"
/db_xref="GeneID:852768"
CDS complement(301537..303411)
/gene="CUE3"
/locus_tag="YGL110C"
/note="hypothetical protein; has a CUE domain that binds
ubiquitin, which may facilitate intramolecular
monoubiquitination"
/codon_start=1
/product="Cue3p"
/protein_id="NP_011405.1"
/db_xref="GI:6321328"
/db_xref="SGD:S000003078"
/db_xref="GeneID:852768"
/translation="MLSRYNRVIEINGGNADISLPIVKFPPFKLRAQLIEKDPVVWLH
LIETYVTYFEYLMQGANVELLDESTLDHLRLFLRTYLHEIADEEGKLLSLGINHDVSE
QLYLLKGWIFSLIKKCGLLHLQIFGDSLWNLIKVYVRRNPDSIRGLIDGSLKPRINTQ
RVQLDKSYQVQQHLKQLIESGKFKRIDLRCVEDLLSAKSMQPNKFAENFFTANWIEIL
EALWAKGQGRGHKEARELIIISLFSVSADRLLKITKELGISNFETLALYPLLGTMLIN
EGVHKRLPDLKSKLLFLNLGGLSMDEGDHMSYPTSSGTEVNEEQLSALMELFPQFSKY
QLSQTLLAYDNNIELVTNKIFEDPTIIEAFSREPAEEEVEPVSDGDNASFTEELSILD
RGDSSKNKELDKKIISEGVPDELRNKTLTRALKLLYEADEDERDDTYDEADVNRSDPS
KRIGLQEDEESYDTKDDSNEVRQDHNYHIVEAYLWNLLKEDPKLFERSKRGTKVRKTM
KEMTSWSDEKIEGWCRMLERSPTRARLLEKKFMFKGNSKTGKTSYVHNRDSQNDGNVV
KEQAKQKKSENIKKHEPQSTEQKKRQHAKNEKRKGARANHNRKKGHDKKLARAGNNAI
"
gene complement(303649..304071)
/locus_tag="YGL108C"
/db_xref="GeneID:852770"
mRNA complement(303649..304071)
/locus_tag="YGL108C"
/product="hypothetical protein"
/transcript_id="NM_001180973.3"
/db_xref="GI:398364498"
/db_xref="GeneID:852770"
CDS complement(303649..304071)
/locus_tag="YGL108C"
/note="hypothetical protein, predicted to be
palmitoylated; green fluorescent protein (GFP)-fusion
protein localizes to the cell periphery; protein abundance
increases in response to DNA replication stress"
/codon_start=1
/product="hypothetical protein"
/protein_id="NP_011407.3"
/db_xref="GI:398364499"
/db_xref="SGD:S000003076"
/db_xref="GeneID:852770"
/translation="MGLCGSKTQPMPSQTTTVATKARTKPINRDTVKSKQELRHKEKK
DKKKKTQLKSTTVPVVQRKEGSKLTDTSDPSKNKVSPKEAARLAAEKRFQETNEKYNK
GELGKKLAQERAKSHKTRLMEEAEKKHAERERENMIYD"
gene complement(304333..306273)
/gene="RMD9"
/locus_tag="YGL107C"
/db_xref="GeneID:852771"
mRNA complement(304333..306273)
/gene="RMD9"
/locus_tag="YGL107C"
/product="Rmd9p"
/transcript_id="NM_001180972.1"
/db_xref="GI:296144940"
/db_xref="GeneID:852771"
CDS complement(304333..306273)
/gene="RMD9"
/locus_tag="YGL107C"
/note="Mitochondrial protein required for respiratory
growth; mutant phenotype and genetic interactions suggest
a role in delivering mt mRNAs to ribosomes; located on
matrix face of the inner membrane and loosely associated
with mitoribosomes"
/codon_start=1
/product="Rmd9p"
/protein_id="NP_011408.1"
/db_xref="GI:6321331"
/db_xref="SGD:S000003075"
/db_xref="GeneID:852771"
/translation="MMLRRNAVRSLKTMEISVSNVVNSGSIAMLRGKLANVVLSDRTY
HSSPIFHKNVPKGVLDKKNGREQRKTEQNVFNVDPASPWRHELLSFDECVSSALKYST
TPLQNTYKRIGNNQLNKNPSFAMFWDSMGRAMELYYSLRESPDFNAYRVSRLIHLLHN
GLRSTRDQLVKLSRKPDYDSQSFHKEMMNFLCNSLKDISDDILIGKVSVSGYGATHLL
TSFKELSFDDDCIRIWEASKNLSDETTSQAFQEPKVVGFMLPLLYAKTRSLTEPNELY
NQIIQSKEFIHPNLYSGLIKVFIKAEDYEKALSLFGQLCEKAEVRNYGYLIETHLSFI
GDSKNLTLAESFFDKIINDEMPYKIILQVSTVNSFLQNIWKAQNDFDHVYRIWEKAVK
FYGNTVNPGILSSLNNTFFTIFFENYINDNINGFRKLQEIITFYSGVKKIDEPFFNVM
LTRASIWHERSIIDFIDKNYTLYHIPRTIISYRILLKSLGSIDNTNNEEILDRWLELV
KKLNELGQQYIANADLSALRDATVVWSQSKRDEKVFSAKAKGTPATTTTTEDDIKVPK
PLENLKNEDSTSNSEDRIELYLKILKRYTPYFRATKQVYRYTTGCAESYPILNEYLSG
YSDLSAEDIPVPQLHSFIAKEQ"
gene 306560..307009
/gene="MLC1"
/locus_tag="YGL106W"
/db_xref="GeneID:852772"
mRNA 306560..307009
/gene="MLC1"
/locus_tag="YGL106W"
/product="Mlc1p"
/transcript_id="NM_001180971.1"
/db_xref="GI:296144941"
/db_xref="GeneID:852772"
CDS 306560..307009
/gene="MLC1"
/locus_tag="YGL106W"
/note="Essential light chain for Myo1p, light chain for
Myo2p; stabilizes Myo2p by binding to the neck region;
interacts with Myo1p, Iqg1p, and Myo2p to coordinate
formation and contraction of the actomyosin ring with
targeted membrane deposition"
/codon_start=1
/product="Mlc1p"
/protein_id="NP_011409.1"
/db_xref="GI:6321332"
/db_xref="SGD:S000003074"
/db_xref="GeneID:852772"
/translation="MSATRANKDIFTLFDKKGQGAIAKDSLGDYLRAIGYNPTNQLVQ
DIINADSSLRDASSLTLDQITGLIEVNEKELDATTKAKTEDFVKAFQVFDKESTGKVS
VGDLRYMLTGLGEKLTDAEVDELLKGVEVDSNGEIDYKKFIEDVLRQ"
gene 307437..308567
/gene="ARC1"
/locus_tag="YGL105W"
/db_xref="GeneID:852773"
mRNA 307437..308567
/gene="ARC1"
/locus_tag="YGL105W"
/product="Arc1p"
/transcript_id="NM_001180970.1"
/db_xref="GI:296144942"
/db_xref="GeneID:852773"
CDS 307437..308567
/gene="ARC1"
/locus_tag="YGL105W"
/note="Protein that binds tRNA and methionyl- and
glutamyl-tRNA synthetases (Mes1p and Gus1p), delivering
tRNA to them, stimulating catalysis, and ensuring their
localization to the cytoplasm; also binds quadruplex
nucleic acids; protein abundance increases in response to
DNA replication stress"
/codon_start=1
/product="Arc1p"
/protein_id="NP_011410.1"
/db_xref="GI:6321333"
/db_xref="SGD:S000003073"
/db_xref="GeneID:852773"
/translation="MSDLVTKFESLIISKYPVSFTKEQSAQAAQWESVLKSGQIQPHL
DQLNLVLRDNTFIVSTLYPTSTDVHVFEVALPLIKDLVASSKDVKSTYTTYRHILRWI
DYMQNLLEVSSTDKLEINHDLDLPHEVIEKKKKAPAGGAADAAAKADEDVSKKAKKQD
HPRGKPDEETLKKLREEAKAKKAAKKAANAKQQQEQQNKAPEKPKPSAIDFRVGFIQK
AIKHPDADSLYVSTIDVGDEEGPRTVCSGLVKHFPLDAMQERYVVVVCNLKPVNMRGI
KSTAMVLCGSNDDKVEFVEPPKDSKAGDKVFFEGFGDEAPMKQLNPKKKIWEHLQPHF
TTNDGLEVIFKDEEEKDHPVRKLTNAKGESFKVASIANAQVR"
gene complement(308713..310173)
/gene="VPS73"
/locus_tag="YGL104C"
/db_xref="GeneID:852774"
mRNA complement(308713..310173)
/gene="VPS73"
/locus_tag="YGL104C"
/product="Vps73p"
/transcript_id="NM_001180969.3"
/db_xref="GI:398364510"
/db_xref="GeneID:852774"
CDS complement(308713..310173)
/gene="VPS73"
/locus_tag="YGL104C"
/note="Mitochondrial protein; mutation affects vacuolar
protein sorting; putative transporter; member of the sugar
porter family"
/codon_start=1
/product="Vps73p"
/protein_id="NP_011411.3"
/db_xref="GI:398364511"
/db_xref="SGD:S000003072"
/db_xref="GeneID:852774"
/translation="MNRILSSASLLSNVSMPRQNKHKITKALCYAIIVASIGSIQFGY
HLSELNAPQQVLSCSEFDIPMEGYPYDRTWLGKRGYKQCIPLNDEQIGIVTSVFCIGG
ILGSYFATSLANIYGRKFSSLINCTLNIVGSLIIFNSNSYRGLIIGRILVGISCGSLI
VIIPLFIKEVAPSGWEGLLGSMTQICIRLGVLLTQGIALPLTDSYRWRWILFGSFLIA
VLNFFMWFIVDESPKWLLAHGRVTDAKLSLCKLRGVTFDEAAQEIQDWQLQIESGDPL
IEPTTTNSISGSNSLWKYLRDRTNVKSRHVITVLLFGQQFCGINSIVLYGTKIISQLY
PQHAIRINFFISMVNVLVTILVSLLIHSLPRKPLLMTSTVLVSVTAFIMGIAMNHNKM
NLLIVFSFIYMGVFTMGLNPLPFIIMREVSKPQDMVLAQRYGTICNWVGTFIIAYTFP
IIHDVLSGYVFIIFAIIACSISAFIWKKVPETKRSG"
gene 310967..311927
/gene="RPL28"
/locus_tag="YGL103W"
/gene_synonym="CYH2"
/db_xref="GeneID:852775"
mRNA join(310967..311015,311527..311927)
/gene="RPL28"
/locus_tag="YGL103W"
/gene_synonym="CYH2"
/product="ribosomal 60S subunit protein L28"
/transcript_id="NM_001180968.1"
/db_xref="GI:296144944"
/db_xref="GeneID:852775"
CDS join(310967..311015,311527..311927)
/gene="RPL28"
/locus_tag="YGL103W"
/gene_synonym="CYH2"
/note="Ribosomal 60S subunit protein L28; homologous to
mammalian ribosomal protein L27A and bacterial L15; may
have peptidyl transferase activity; can mutate to
cycloheximide resistance"
/codon_start=1
/product="ribosomal 60S subunit protein L28"
/protein_id="NP_011412.1"
/db_xref="GI:6321335"
/db_xref="SGD:S000003071"
/db_xref="GeneID:852775"
/translation="MPSRFTKTRKHRGHVSAGKGRIGKHRKHPGGRGMAGGQHHHRIN
MDKYHPGYFGKVGMRYFHKQQAHFWKPVLNLDKLWTLIPEDKRDQYLKSASKETAPVI
DTLAAGYGKILGKGRIPNVPVIVKARFVSKLAEEKIRAAGGVVELIA"
gene 312193..312840
/locus_tag="YGL101W"
/db_xref="GeneID:852777"
mRNA 312193..312840
/locus_tag="YGL101W"
/product="hypothetical protein"
/transcript_id="NM_001180966.1"
/db_xref="GI:296144945"
/db_xref="GeneID:852777"
CDS 312193..312840
/locus_tag="YGL101W"
/note="hypothetical protein; non-essential gene with
similarity to YBR242W; interacts with the DNA helicase
Hpr5p"
/codon_start=1
/product="hypothetical protein"
/protein_id="NP_011414.1"
/db_xref="GI:6321337"
/db_xref="SGD:S000003069"
/db_xref="GeneID:852777"
/translation="MTAVNIWKPEDNIPREILAILSKPHPNYQLAFLNIIQLLKTQRR
TGWVDHGIDPCESISDHMYRMGLTTMLITDKNVDRNKCIRIALVHDFAESLVGDITPN
DPMTKEEKHRREFETVKYLCESIIRPCSESASREILDDWLAYEKQTCLEGRYVKDIDK
YEMLVQCFEYEQKYNGKKDLKQFLGAINDIKTDEVKKWTQSLLEDRQAFFDSLKE"
gene 313234..314283
/gene="SEH1"
/locus_tag="YGL100W"
/db_xref="GeneID:852778"
mRNA 313234..314283
/gene="SEH1"
/locus_tag="YGL100W"
/product="Seh1p"
/transcript_id="NM_001180965.1"
/db_xref="GI:296144946"
/db_xref="GeneID:852778"
CDS 313234..314283
/gene="SEH1"
/locus_tag="YGL100W"
/note="Component of two distinct complexes; subunit of the
Nup84 nuclear pore sub-complex (NPC) and the
Seh1-associated (SEA) complex; the the NUP84 subcomplex
contributes to nucleocytoplasmic transport and NPC
biogenesis; the SEA complex is a coatamer-related complex
that associates dynamically with the vacuole; homologous
to human SEH1"
/codon_start=1
/product="Seh1p"
/protein_id="NP_011415.1"
/db_xref="GI:6321338"
/db_xref="SGD:S000003068"
/db_xref="GeneID:852778"
/translation="MQPFDSGHDDLVHDVVYDFYGRHVATCSSDQHIKVFKLDKDTSN
WELSDSWRAHDSSIVAIDWASPEYGRIIASASYDKTVKLWEEDPDQEECSGRRWNKLC
TLNDSKGSLYSVKFAPAHLGLKLACLGNDGILRLYDALEPSDLRSWTLTSEMKVLSIP
PANHLQSDFCLSWCPSRFSPEKLAVSALEQAIIYQRGKDGKLHVAAKLPGHKSLIRSI
SWAPSIGRWYQLIATGCKDGRIRIFKITEKLSPLASEESLTNSNMFDNSADVDMDAQG
RSDSNTEEKAELQSNLQVELLSEHDDHNGEVWSVSWNLTGTILSSAGDDGKVRLWKAT
YSNEFKCMSVITAQQ"
gene 314631..316553
/gene="LSG1"
/locus_tag="YGL099W"
/gene_synonym="KRE35"
/db_xref="GeneID:852779"
mRNA 314631..316553
/gene="LSG1"
/locus_tag="YGL099W"
/gene_synonym="KRE35"
/product="Lsg1p"
/transcript_id="NM_001180964.3"
/db_xref="GI:398364524"
/db_xref="GeneID:852779"
CDS 314631..316553
/gene="LSG1"
/locus_tag="YGL099W"
/gene_synonym="KRE35"
/note="Putative GTPase involved in 60S ribosomal subunit
biogenesis; required for the release of Nmd3p from 60S
subunits in the cytoplasm"
/codon_start=1
/product="Lsg1p"
/protein_id="NP_011416.3"
/db_xref="GI:398364525"
/db_xref="SGD:S000003067"
/db_xref="GeneID:852779"
/translation="MPPKEAPKKWKAPKGPKPTHRKNKNKLELGRAIKYARQKENAIE
YLPDGEMRFTTDKHEANWVKLRSVTQESALDEFLSTAALADKDFTADRHSNVKIIRMD
SGNDSATSQGFSMTNEQRGNLNAKQRALAKDLIVPRRPEWNEGMSKFQLDRQEKEAFL
EWRRKLAHLQESNEDLLLTPFERNIEVWKQLWRVVERSDLVVQIVDARNPLLFRSVDL
ERYVKESDDRKANLLLVNKADLLTKKQRIAWAKYFISKNISFTFYSALRANQLLEKQK
EMGEDYREQDFEEADKEGFDADEKVMEKVKILSIDQLEELFLSKAPNEPLLPPLPGQP
PLINIGLVGYPNVGKSSTINSLVGAKKVSVSSTPGKTKHFQTIKLSDSVMLCDCPGLV
FPNFAYNKGELVCNGVLPIDQLRDYIGPAGLVAERIPKYYIEAIYGIHIQTKSRDEGG
NGDIPTAQELLVAYARARGYMTQGYGSADEPRASRYILKDYVNGKLLYVNPPPHLEDD
TPYTREECEEFNKDLYVFDRLPDTRKEQVQNAAKAKGIDIVDLARDLNQLTFSAHTGG
DTQKEAKSVTHGGKQAALYNAAEDLDRDFFKMNNVEGRLSTPFHKVQNSSAGKRHNKK
NKSKNAKSKVFSIENN"
gene 316788..317055
/locus_tag="snR82"
/db_xref="GeneID:9164893"
ncRNA 316788..317055
/locus_tag="snR82"
/ncRNA_class="snoRNA"
/product="SNR82"
/note="H/ACA box small nucleolar RNA (snoRNA); guides
pseudouridylation of large subunit (LSU) rRNA at positions
U1110, U2349, and U2351"
/db_xref="SGD:S000028467"
/db_xref="GeneID:9164893"
gene 317342..318079
/gene="USE1"
/locus_tag="YGL098W"
/gene_synonym="SLT1"
/db_xref="GeneID:852780"
mRNA 317342..318079
/gene="USE1"
/locus_tag="YGL098W"
/gene_synonym="SLT1"
/product="Use1p"
/transcript_id="NM_001180963.1"
/db_xref="GI:296144948"
/db_xref="GeneID:852780"
CDS 317342..318079
/gene="USE1"
/locus_tag="YGL098W"
/gene_synonym="SLT1"
/note="Essential SNARE protein localized to the ER,
involved in retrograde traffic from the Golgi to the ER;
forms a complex with the SNAREs Sec22p, Sec20p and Ufe1p"
/codon_start=1
/product="Use1p"
/protein_id="NP_011417.1"
/db_xref="GI:6321340"
/db_xref="SGD:S000003066"
/db_xref="GeneID:852780"
/translation="MAETSNDPFLSYVLSSKQLTNLNRLRRKAVTKQLGSSDDNKVSE
EFLRYQHTYQREAFEYLQTKHDAHKIMESQYEQYQSSSKTRRYSIDLDSVDAVDTESQ
TEYPNEEFIDRNEDSEAVMELRKRLLGKGQNKGLGYETTKSVDRQIEDQDTLQQDLIQ
DMSKLVGSLKQGAVAFQSALDEDKQVLGAAEIGIQVASQGLMDVSGKLRKYDKSKLSY
LFYITVFIFMILGLVFTFIIIQLFPAL"
LTR 318697..318860
/note="Ty1 LTR"
/db_xref="SGD:S000006942"
LTR complement(319009..319341)
/note="Ty1 LTR"
/db_xref="SGD:S000006936"
LTR complement(319423..319762)
/note="Ty3 LTR"
/db_xref="SGD:S000006937"
gene 319781..319852
/locus_tag="tH(GUG)G2"
/db_xref="GeneID:852781"
tRNA 319781..319852
/locus_tag="tH(GUG)G2"
/product="tRNA-His"
/note="Histidine tRNA (tRNA-His), predicted by tRNAscan-SE
analysis"
/db_xref="SGD:S000006596"
/db_xref="GeneID:852781"
LTR complement(320355..320707)
/note="Ty4 LTR"
/db_xref="SGD:S000006939"
gene 321782..323230
/gene="SRM1"
/locus_tag="YGL097W"
/gene_synonym="MTR1; PRP20"
/db_xref="GeneID:852782"
mRNA 321782..323230
/gene="SRM1"
/locus_tag="YGL097W"
/gene_synonym="MTR1; PRP20"
/product="Srm1p"
/transcript_id="NM_001180962.1"
/db_xref="GI:296144949"
/db_xref="GeneID:852782"
CDS 321782..323230
/gene="SRM1"
/locus_tag="YGL097W"
/gene_synonym="MTR1; PRP20"
/note="Nucleotide exchange factor for Gsp1p, localizes to
the nucleus, required for nucleocytoplasmic trafficking of
macromolecules; suppressor of the pheromone response
pathway; potentially phosphorylated by Cdc28p"
/codon_start=1
/product="Srm1p"
/protein_id="NP_011418.1"
/db_xref="GI:6321341"
/db_xref="SGD:S000003065"
/db_xref="GeneID:852782"
/translation="MVKRTVATNGDASGAHRAKKMSKTHASHIINAQEDYKHMYLSVQ
PLDIFCWGTGSMCELGLGPLAKNKEVKRPRLNPFLPRDEAKIISFAVGGMHTLALDEE
SNVWSWGCNDVGALGRDTSNAKEQLKDMDADDSSDDEDGDLNELESTPAKIPRESFPP
LAEGHKVVQLAATDNMSCALFSNGEVYAWGTFRCNEGILGFYQDKIKIQKTPWKVPTF
SKYNIVQLAPGKDHILFLDEEGMVFAWGNGQQNQLGRKVMERFRLKTLDPRPFGLRHV
KYIASGENHCFALTKDNKLVSWGLNQFGQCGVSEDVEDGALVTKPKRLALPDNVVIRS
IAAGEHHSLILSQDGDLYSCGRLDMFEVGIPKDNLPEYTYKDVHGKARAVPLPTKLNN
VPKFKSVAAGSHHSVAVAQNGIAYSWGFGETYAVGLGPFEDDTEVPTRIKNTATQDHN
IILVGCGGQFSVSGGVKLSDEDAEKRADEMDD"
gene 325331..326161
/gene="TOS8"
/locus_tag="YGL096W"
/db_xref="GeneID:852783"
mRNA 325331..326161
/gene="TOS8"
/locus_tag="YGL096W"
/product="Tos8p"
/transcript_id="NM_001180961.1"
/db_xref="GI:296144950"
/db_xref="GeneID:852783"
CDS 325331..326161
/gene="TOS8"
/locus_tag="YGL096W"
/note="Homeodomain-containing protein and putative
transcription factor; found associated with chromatin;
target of SBF transcription factor; induced during meiosis
and under cell-damaging conditions; TOS8 has a paralog,
CUP9, that arose from the whole genome duplication"
/codon_start=1
/product="Tos8p"
/protein_id="NP_011419.1"
/db_xref="GI:6321342"
/db_xref="SGD:S000003064"
/db_xref="GeneID:852783"
/translation="MGTSIVNLNQKIELPPIQVLFESLNRENETKPHFEERRLYQPNP
SFVPRTNIAVGSPVNPVPVSSPVFFIGPSPQRSIQNHNAIMTQNIRQYPVIYNNNREV
ISTGERNYIITVGGPPVTSSQPEYEHISTPNFYQEQRLAQPHPVNESMMIGGYTNPQP
ISISRGKMLSGNISTNSVRGSNNGYSAKEKKHKAHGKRSNLPKATVSILNKWLHEHVN
NPYPTVQEKRELLAKTGLTKLQISNWFINARRRKIFSGQNDANNFRRKFSSSTNLAKF
"
LTR 327904..328224
/note="Ty1 LTR"
/db_xref="SGD:S000006943"
gene 328583..328654
/gene="SOE1"
/locus_tag="tE(UUC)G1"
/db_xref="GeneID:852784"
tRNA 328583..328654
/gene="SOE1"
/locus_tag="tE(UUC)G1"
/product="tRNA-Glu"
/note="Glutamate tRNA (tRNA-Glu), predicted by tRNAscan-SE
analysis; thiolation of uridine at wobble position (34)
requires Ncs6p; can mutate to become a missense suppressor
tRNA that inserts glutamate residues at lysine codons;
target of K. lactis zymocin"
/db_xref="SGD:S000006553"
/db_xref="GeneID:852784"
gene complement(328874..330607)
/gene="VPS45"
/locus_tag="YGL095C"
/gene_synonym="STT10; VPL28"
/db_xref="GeneID:852785"
mRNA complement(328874..330607)
/gene="VPS45"
/locus_tag="YGL095C"
/gene_synonym="STT10; VPL28"
/product="Vps45p"
/transcript_id="NM_001180960.3"
/db_xref="GI:398364536"
/db_xref="GeneID:852785"
CDS complement(328874..330607)
/gene="VPS45"
/locus_tag="YGL095C"
/gene_synonym="STT10; VPL28"
/note="Protein of the Sec1p/Munc-18 family, essential for
vacuolar protein sorting; required for the function of
Pep12p and the early endosome/late Golgi SNARE Tlg2p;
essential for fusion of Golgi-derived vesicles with the
prevacuolar compartment"
/codon_start=1
/product="Vps45p"
/protein_id="NP_011420.3"
/db_xref="GI:398364537"
/db_xref="SGD:S000003063"
/db_xref="GeneID:852785"
/translation="MNLFDVADFYINKIVTSQSKLSVANVNEHQRIKVLLLDKNTTPT
ISLCATQSELLKHEIYLVERIENEQREVSRHLRCLVYVKPTEETLQHLLRELRNPRYG
EYQIFFSNIVSKSQLERLAESDDLEAVTKVEEIFQDFFILNQDLFSFDLQPREFLSNK
LVWSEGGLTKCTNSLVSVLLSLKIKPDIRYEGASKICERLAKEVSYEIGKNERTFFDF
PVMDSTPVLLILDRNTDPITPLLQPWTYQSMINEYIGIKRNIVDLSKVPRIDKDLEKV
TLSSKQDAFFRDTMYLNFGELGDKVKQYVTTYKDKTQTNSQINSIEDIKNFIEKYPEF
RKLSGNVAKHMAIVGELDRQLKIKNIWEISEIEQNLSAHDANEEDFSDLIKLLQNEAV
DKYYKLKLACIYSLNNQTSSDKIRQLVEILSQQLPPEDVNFFHKFKSLFSRQDKMTQS
NHDKDDILTELARRFNSRMNSKSNTAENVYMQHIPEISSLLTDLSKNALFRDRFKEID
TQGHRVIGNQQSKDIPQDVILFVIGGVTYEEARLVHDFNGTMNNRMRVVLGGTSILST
KEYMDSIRSAK"
gene complement(331118..334465)
/gene="PAN2"
/locus_tag="YGL094C"
/db_xref="GeneID:852786"
mRNA complement(331118..334465)
/gene="PAN2"
/locus_tag="YGL094C"
/product="Pan2p"
/transcript_id="NM_001180959.1"
/db_xref="GI:296144952"
/db_xref="GeneID:852786"
CDS complement(331118..334465)
/gene="PAN2"
/locus_tag="YGL094C"
/EC_number="3.1.13.4"
/note="Essential subunit of the Pan2p-Pan3p
poly(A)-ribonuclease complex, which acts to control
poly(A) tail length and regulate the stoichiometry and
activity of postreplication repair complexes"
/codon_start=1
/product="Pan2p"
/protein_id="NP_011421.1"
/db_xref="GI:6321344"
/db_xref="SGD:S000003062"
/db_xref="GeneID:852786"
/translation="MNNWQHFFNNPVDLSEHLKKPYFRFDNRDKEITAISFDEKANLI
WSGDSYGCISSYDPTFQLYTRYRGHIGGNSVKDILSHRDGILSISEDSLHFANRRGVT
KLNLTSIDIAAFSELNTMCYSPHSLKNNIYCGGDNTNWGIASIDLNRGCLDSLLNYSS
KVKLMCSNNKVLSIGRQTGTVDLLDPTSNRTIKSFNAHSASISAMDLRDNTLVTVGKS
KRFYNLYADPFVNVYDLRTMRQLPPVSFSKGTTMGSGGADFVQLHPLLPTVMIVASSS
GSFDFIDLSNPTLRTQYVHPCQSIKKLCLSPNGDVLGILEADNHLDTWRRSSNNMGMF
TNTPEMLAYPDYFNDITSDGPISVDDETYPLSSVGMPYYLDKLLSAWPPVVFKSEGTI
PQLTGKSPLPSSGKLKSNLAVISSQNEKLSTQEFPLLRYDRTKYGMRNAIPDYVCLRD
IRKQITSGLETSDIQTYTSINKYEVPPAYSRLPLTSGRFGTDNFDFTPFNNTEYSGLD
PDVDNHYTNAIIQLYRFIPEMFNFVVGCLKDENFETTLLTDLGYLFDMMERSHGKICS
SSNFQASLKSLTDKRQLENGEPQEHLEEYLESLCIRESIEDFNSSESIKRNMPQKFNR
FLLSQLIKEEAQTVNHNITLNQCFGLETEIRTECSCDHYDTTVKLLPSLSISGINKTV
IKQLNKKSNGQNILPYIEYAMKNVTQKNSICPTCGKTETITQECTVKNLPSVLSLELS
LLDTEFSNIRSSKNWLTSEFYGSIIKNKAVLRSTASELKGTSHIFKYELNGYVAKITD
NNNETRLVTYVKKYNPKENCFKWLMFNDYLVVEITEEEALKMTYPWKTPEIIIYCDAE
ELRKPFFSVDTYSINYDILFRDYFANGIRDTARREYKLLTHDEAPKSGTLVAIDAEFV
SLQSELCEIDHQGIRSIIRPKRTALARISIIRGEEGELYGVPFVDDYVVNTNHIEDYL
TRYSGILPGDLDPEKSTKRLVRRNVVYRKVWLLMQLGCVFVGHGLNNDFKHININVPR
NQIRDTAIYFLQGKRYLSLRYLAYVLLGMNIQEGNHDSIEDAHTALILYKKYLHLKEK
AIFEKVLNSVYEEGRAHNFKVPETSKG"
gene 334886..337639
/gene="SPC105"
/locus_tag="YGL093W"
/db_xref="GeneID:852787"
mRNA 334886..337639
/gene="SPC105"
/locus_tag="YGL093W"
/product="Spc105p"
/transcript_id="NM_001180958.1"
/db_xref="GI:296144953"
/db_xref="GeneID:852787"
CDS 334886..337639
/gene="SPC105"
/locus_tag="YGL093W"
/note="Subunit of a kinetochore-microtubule binding
complex with Kre28p that bridges centromeric
heterochromatin and kinetochore MAPs and motors; required
for sister chromatid bi-orientation and kinetochore
binding of SAC components"
/codon_start=1
/product="Spc105p"
/protein_id="NP_011422.1"
/db_xref="GI:6321345"
/db_xref="SGD:S000003061"
/db_xref="GeneID:852787"
/translation="MNVDERSRIGGREKDAGPGKGILKQNQSSQMTSSFLENPGVRIP
TRIITKKEVLDGSNTTSRINTSNLQSMVKRRVSFAPDVTLHSFTFVPEQNNEIKEPRR
RKTSTNSPTKISSQEEPLVTSTQIDDARTEEKTAAEEDPDTSGMELTEPIVATPDSNK
ASQHDPTSMEMTEVFPRSIRQKNPDVEGESIESSQQIDDVEAVREETMELTAIHNVHD
YDSISKDTVEGEPIDLTEYESKPYVPNSVSRSTGKSSDYSVERSNDKSDLSKSENKTN
SSQPMEITDIFHADPQNPMSLHSDNNINNDGNEMELTQIQTNFDRDNHHIDESPSEKH
AFSSNKRRKLDTVSDYAASVTTPVKEAKDTSGEDNDGDLEMMEKMSPITFSDVDNKIG
TRSNDVFTIEPGTEDTGMQTATDDEEDGENVDDNGNKIVEKTRLPEIDKEGQSGIALP
TQDYTLREFINEVGVGFLDTKLIDDLDKKVNFPLNSFNFVENQRIDNVFSAFYIDIPI
LEVEAFRCKELWRSINESKDKFKDFEAQIDKSHPPLLLQEYFSSDEKMKQLMRDQLQL
VKGYSKLEAAMEWYEWRKKQLNGLELILAENLNTLKREYEKLNEEVEKVNSIRGKIRK
LNEAIKEEIRSLKNLPSDSYKPTLMNRIKIEAFKQELMEHSISLSSSNDFTQEMRSLK
LAIAKKSNDILTLRSEVASIDKKIEKRKLFTRFDLPKLRDTLKILESLTGVRFLKFSK
ATLSIAFLQLDDLRVDINLANFKNNPLSSMKVMNDSNNDDMSYHLFTMLLKNVEAEHQ
DSMLSNLFFAMKKWRPLLKYIKLLKLLFPVKITQTEEEEALLQFKDYDRRNKTAFFYV
ISLVSFAQGVFSENGQIPMKVHISTQQDYSPSREVLSDRITHKISGVLPSFTKSRIHL
EFT"
gene 337906..341859
/gene="NUP145"
/locus_tag="YGL092W"
/gene_synonym="RAT10"
/db_xref="GeneID:852788"
mRNA 337906..341859
/gene="NUP145"
/locus_tag="YGL092W"
/gene_synonym="RAT10"
/product="Nup145p"
/transcript_id="NM_001180957.1"
/db_xref="GI:296144954"
/db_xref="GeneID:852788"
CDS 337906..341859
/gene="NUP145"
/locus_tag="YGL092W"
/gene_synonym="RAT10"
/EC_number="3.4.21.-"
/note="Essential protein with distinct roles in two
nuclear pore subcomplexes; catalyzes its own proteolytic
cleavage in vivo to generate a C-terminal fragment that is
a structural component of the Nup84p subcomplex (with
roles in NPC biogenesis and localization of genes to the
nuclear periphery), and an N-terminal fragment that is one
of several FG-nucleoporins within the NPC central core
directly responsible for nucleocytoplasmic transport;
homologous to human NUP98"
/codon_start=1
/product="Nup145p"
/protein_id="NP_011423.1"
/db_xref="GI:6321346"
/db_xref="SGD:S000003060"
/db_xref="GeneID:852788"
/translation="MFNKSVNSGFTFGNQNTSTPTSTPAQPSSSLQFPQKSTGLFGNV
NVNANTSTPSPSGGLFNANSNANSISQQPANNSLFGNKPAQPSGGLFGATNNTTSKSA
GSLFGNNNATANSTGSTGLFSGSNNIASSTQNGGLFGNSNNNNITSTTQNGGLFGKPT
TTPAGAGGLFGNSSSTNSTTGLFGSNNTQSSTGIFGQKPGASTTGGLFGNNGASFPRS
GETTGTMSTNPYGINISNVPMAVADMPRSITSSLSDVNGKSDAEPKPIENRRTYSFSS
SVSGNAPLPLASQSSLVSRLSTRLKATQKSTSPNEIFSPSYSKPWLNGAGSAPLVDDF
FSSKMTSLAPNENSIFPQNGFNFLSSQRADLTELRKLKIDSNRSAAKKLKLLSGTPAI
TKKHMQDEQDSSENEPIANADSVTNIDRKENRDNNLDNTYLNGKEQSNNLNKQDGENT
LQHEKSSSFGYWCSPSPEQLERLSLKQLAAVSNFVIGRRGYGCITFQHDVDLTAFTKS
FREELFGKIVIFRSSKTVEVYPDEATKPMIGHGLNVPAIITLENVYPVDKKTKKPMKD
TTKFAEFQVFDRKLRSMREMNYISYNPFGGTWTFKVNHFSIWGLVNEEDAEIDEDDLS
KQEDGGEQPLRKVRTLAQSKPSDKEVILKTDGTFGTLSGKDDSIVEEKAYEPDLSDAD
FEGIEASPKLDVSKDWVEQLILAGSSLRSVFATSKEFDGPCQNEIDLLFSECNDEIDN
AKLIMKERRFTASYTFAKFSTGSMLLTKDIVGKSGVSIKRLPTELQRKFLFDDVYLDK
EIEKVTIEARKSNPYPQISESSLLFKDALDYMEKTSSDYNLWKLSSILFDPVSYPYKT
DNDQVKMALLKKERHCRLTSWIVSQIGPEIEEKIRNSSNEIEQIFLYLLLNDVVRASK
LAIESKNGHLSVLISYLGSNDPRIRDLAELQLQKWSTGGCSIDKNISKIYKLLSGSPF
EGLFSLKELESEFSWLCLLNLTLCYGQIDEYSLESLVQSHLDKFSLPYDDPIGVIFQL
YAANENTEKLYKEVRQRTNALDVQFCWYLIQTLRFNGTRVFSKETSDEATFAFAAQLE
FAQLHGHSLFVSCFLNDDKAAEDTIKRLVMREITLLRASTNDHILNRLKIPSQLIFNA
QALKDRYEGNYLSEVQNLLLGSSYDLAEMAIVTSLGPRLLLSNNPVQNNELKTLREIL
NEFPDSERDKWSVSINVFEVYLKLVLDNVETQETIDSLISGMKIFYDQYKHCREVAAC
CNVMSQEIVSKILEKNNPSIGDSKAKLLELPLGQPEKAYLRGEFAQDLMKCTYKI"
gene complement(342056..343042)
/gene="NBP35"
/locus_tag="YGL091C"
/db_xref="GeneID:852789"
mRNA complement(342056..343042)
/gene="NBP35"
/locus_tag="YGL091C"
/product="Nbp35p"
/transcript_id="NM_001180956.3"
/db_xref="GI:398364552"
/db_xref="GeneID:852789"
CDS complement(342056..343042)
/gene="NBP35"
/locus_tag="YGL091C"
/note="Essential iron-sulfur cluster binding protein
localized in the cytoplasm; forms a complex with Cfd1p
that is involved in iron-sulfur protein assembly in the
cytosol; similar to P-loop NTPases"
/codon_start=1
/product="Nbp35p"
/protein_id="NP_011424.3"
/db_xref="GI:398364553"
/db_xref="SGD:S000003059"
/db_xref="GeneID:852789"
/translation="MTEILPHVNDEVLPAEYELNQPEPEHCPGPESDMAGKSDACGGC
ANKEICESLPKGPDPDIPLITDNLSGIEHKILVLSGKGGVGKSTFAAMLSWALSADED
LQVGAMDLDICGPSLPHMLGCIKETVHESNSGWTPVYVTDNLATMSIQYMLPEDDSAI
IWRGSKKNLLIKKFLKDVDWDKLDYLVIDTPPGTSDEHISINKYMRESGIDGALVVTT
PQEVALLDVRKEIDFCKKAGINILGLVENMSGFVCPNCKGESQIFKATTGGGEALCKE
LGIKFLGSVPLDPRIGKSCDMGESFLDNYPDSPASSAVLNVVEALRDAVGDV"
gene 343319..344584
/gene="LIF1"
/locus_tag="YGL090W"
/db_xref="GeneID:852790"
mRNA 343319..344584
/gene="LIF1"
/locus_tag="YGL090W"
/product="Lif1p"
/transcript_id="NM_001180955.1"
/db_xref="GI:296144956"
/db_xref="GeneID:852790"
CDS 343319..344584
/gene="LIF1"
/locus_tag="YGL090W"
/note="Component of the DNA ligase IV complex that
mediates nonhomologous end joining in DNA double-strand
break repair; physically interacts with Dnl4p and Nej1p;
homologous to mammalian XRCC4 protein"
/codon_start=1
/product="Lif1p"
/protein_id="NP_011425.1"
/db_xref="GI:6321348"
/db_xref="SGD:S000003058"
/db_xref="GeneID:852790"
/translation="MSQLTEFISCIPVVNEEQNEEDERGLCKIQIEDGAMLETLDENS
LSGLRIEKMLVSEGTGIFSKSSFGINDLRIFTGENIDEESKKYVWYELLKMLTGHKVY
IASLDEKVVFTKWTCRMQDDEVWKVVMELESSAIIRKIAELTLHPVKKGEIDLFEMAD
KLYKDICCVNDSYRNIKESDSSNRNRVEQLARERELLDKLLETRDERTRAMMVTLLNE
KKKKIRELHEILRQNNIKLSDDDVLDSALINTEVQKPISELNSPGKRMKRRKTVVEPQ
NLQKKLKDTSRRRANRKISNQSVIKMEDDDFDDFQFFGLSKRPIITAKDKLSEKYDDI
TSFGDDTQSISFESDSSSDVQKHLVSLEDNGIQISAGRSDEDYGDISGSESETDASAG
EKKSSNHSEQSGNDREPCLQTESETDIET"
gene complement(344791..345153)
/gene="MF(ALPHA)2"
/locus_tag="YGL089C"
/db_xref="GeneID:852791"
mRNA complement(344791..345153)
/gene="MF(ALPHA)2"
/locus_tag="YGL089C"
/product="Mf(alpha)2p"
/transcript_id="NM_001180954.1"
/db_xref="GI:296144957"
/db_xref="GeneID:852791"
CDS complement(344791..345153)
/gene="MF(ALPHA)2"
/locus_tag="YGL089C"
/note="Mating pheromone alpha-factor, made by alpha cells;
interacts with mating type a cells to induce cell cycle
arrest and other responses leading to mating; also encoded
by MF(ALPHA)1, which is more highly expressed than
MF(ALPHA)2"
/codon_start=1
/product="Mf(alpha)2p"
/protein_id="NP_011426.1"
/db_xref="GI:6321349"
/db_xref="SGD:S000003057"
/db_xref="GeneID:852791"
/translation="MKFISTFLTFILAAVSVTASSDEDIAQVPAEAIIGYLDFGGDHD
IAFLPFSNATASGLLFINTTIAEAAEKEQNTTLAKREAVADAWHWLNLRPGQPMYKRE
ANADAWHWLQLKPGQPMY"
gene 345986..346230
/locus_tag="snR10"
/db_xref="GeneID:9164894"
ncRNA 345986..346230
/locus_tag="snR10"
/ncRNA_class="snoRNA"
/product="SNR10"
/note="H/ACA box small nucleolar RNA (snoRNA); essential
gene required for for preRNA processing, specifically for
cleavage at sites A1 and A2; also guides pseudouridylation
of large subunit (LSU) rRNA at position U2923"
/db_xref="SGD:S000007499"
/db_xref="GeneID:9164894"
gene complement(346406..346904)
/gene="MMS2"
/locus_tag="YGL087C"
/db_xref="GeneID:852793"
mRNA complement(join(346406..346808,346894..346904))
/gene="MMS2"
/locus_tag="YGL087C"
/product="E2 ubiquitin-conjugating protein MMS2"
/transcript_id="NM_001180952.1"
/db_xref="GI:296144958"
/db_xref="GeneID:852793"
CDS complement(join(346406..346808,346894..346904))
/gene="MMS2"
/locus_tag="YGL087C"
/note="Ubiquitin-conjugating enzyme variant; involved in
error-free postreplication repair; forms a heteromeric
complex with Ubc13p, an active ubiquitin-conjugating
enzyme; cooperates with chromatin-associated RING finger
proteins, Rad18p and Rad5p; protein abundance increases in
response to DNA replication stress"
/codon_start=1
/product="E2 ubiquitin-conjugating protein MMS2"
/protein_id="NP_011428.1"
/db_xref="GI:6321351"
/db_xref="SGD:S000003055"
/db_xref="GeneID:852793"
/translation="MSKVPRNFRLLEELEKGEKGFGPESCSYGLADSDDITMTKWNGT
ILGPPHSNHENRIYSLSIDCGPNYPDSPPKVTFISKINLPCVNPTTGEVQTDFHTLRD
WKRAYTMETLLLDLRKEMATPANKKLRQPKEGETF"
gene 347119..349368
/gene="MAD1"
/locus_tag="YGL086W"
/db_xref="GeneID:852794"
mRNA 347119..349368
/gene="MAD1"
/locus_tag="YGL086W"
/product="Mad1p"
/transcript_id="NM_001180951.3"
/db_xref="GI:398364566"
/db_xref="GeneID:852794"
CDS 347119..349368
/gene="MAD1"
/locus_tag="YGL086W"
/note="Coiled-coil protein involved in the
spindle-assembly checkpoint; phosphorylated by Mps1p upon
checkpoint activation which leads to inhibition of the
activity of the anaphase promoting complex; forms a
complex with Mad2p"
/codon_start=1
/product="Mad1p"
/protein_id="NP_011429.3"
/db_xref="GI:398364567"
/db_xref="SGD:S000003054"
/db_xref="GeneID:852794"
/translation="MDVRAALQCFFSALSGRFTGKKLGLEIYSIQYKMSNSGGSSPFL
ESPGGSPDVGSTNGQSNRQIQALQFKLNTLQNEYEIEKLQLQKQTNILEKKYKATIDE
LEKALNDTKYLYESNDKLEQELKSLKERSANSMNDKDKCIEELRTTLQNKDLEMETLR
QQYDSKLSKVTNQCDHFKLEAESSHSLLMKYEKEIKRQSVDIKDLQHQVMEKDDELSS
VKASKMINSHPNYSTEEFNELTEMNKMIQDQVQYTKELELANMQQANELKKLKQSQDT
STFWKLENEKLQNKLSQLHVLESQYENLQLENIDLKSKLTKWEIYNDSDDDDDNNVNN
NDNNNNNKNDNNNDNNNDTSNNNNINNNNRTKNNIRNNPEEIIRDWKLTKKECLILTD
MNDKLRLDNNNLKLLNDEMALERNQILDLNKNYENNIVNLKRLNHELEQQKSLSFEEC
RLLREQLDGLYSAQNNALLEVENSETHASNKNVNEDMNNLIDTYKNKTEDLTNELKKL
NDQLLSNSNDVETQRKKRKLTSDQIGLNYSQRLNELQLENVSVSRELSKAQTTIQLLQ
EKLEKLTKLKEKKIRILQLRDGPFIKDQFIKKNKLLLLEKENADLLNELKKNNPAVET
VPISVYDSLNFELKQFEQEVFKSNKRFSRLKQVFNNKSLEFIDVVNSLLGFKLEFQQD
SRVKIFSCFKPEKYLIADLNENTLKSNLDADIEGWDDLMNLWVEDRGQLPCFLATITL
RLWEQRQAK"
gene 349616..350440
/gene="LCL3"
/locus_tag="YGL085W"
/db_xref="GeneID:852795"
mRNA 349616..350440
/gene="LCL3"
/locus_tag="YGL085W"
/product="Lcl3p"
/transcript_id="NM_001180950.1"
/db_xref="GI:296144960"
/db_xref="GeneID:852795"
CDS 349616..350440
/gene="LCL3"
/locus_tag="YGL085W"
/EC_number="3.1.-.-"
/note="hypothetical protein; mutant has long chronological
lifespan; has homology to Staphylococcus aureus nuclease;
GFP-fusion protein localizes to mitochondria; is induced
in response to the DNA-damaging agent MMS"
/codon_start=1
/product="Lcl3p"
/protein_id="NP_011430.1"
/db_xref="GI:6321353"
/db_xref="SGD:S000003053"
/db_xref="GeneID:852795"
/translation="MREGDSNSKKSADVAVLSIILTGSTLTLIYTYKRYLTQFKRTND
IPRRIFRKHWLYGKVTSVGDGDNFHFFHMPGGIRGGWGWLRPVPQMIKNDSTAEKLVG
DSRNMRFFNFNWITHGRSTKSKIQKAKSQFLKLNVPYKNRKNLPTIPIRLCGIDAPER
AHFGNPAQPFGNEALIWLQNRILGKKVWVKPLSIDQYNRCVARVSYWDWFGGWKDLSL
EMLKDGLAVVYEGKVNTEFDDREDKYRYYEFLARSRKKGLWIQNKFETPGEYKKRI"
gene complement(350616..352298)
/gene="GUP1"
/locus_tag="YGL084C"
/db_xref="GeneID:852796"
mRNA complement(350616..352298)
/gene="GUP1"
/locus_tag="YGL084C"
/product="Gup1p"
/transcript_id="NM_001180949.1"
/db_xref="GI:296144961"
/db_xref="GeneID:852796"
CDS complement(350616..352298)
/gene="GUP1"
/locus_tag="YGL084C"
/note="Plasma membrane protein involved in remodeling GPI
anchors; member of the MBOAT family of putative
membrane-bound O-acyltransferases; proposed to be involved
in glycerol transport"
/codon_start=1
/product="Gup1p"
/protein_id="NP_011431.1"
/db_xref="GI:6321354"
/db_xref="SGD:S000003052"
/db_xref="GeneID:852796"
/translation="MSLISILSPLITSEGLDSRIKPSPKKDASTTTKPSLWKTTEFKF
YYIAFLVVVPLMFYAGLQASSPENPNYARYERLLSQGWLFGRKVDNSDSQYRFFRDNF
ALLSVLMLVHTSIKRIVLYSTNITKLRFDLIFGLIFLVAAHGVNSIRILAHMLILYAI
AHVLKNFRRIATISIWIYGISTLFINDNFRAYPFGNICSFLSPLDHWYRGIIPRWDVF
FNFTLLRVLSYNLDFLERWENLQKKKSPSYESKEAKSAILLNERARLTAAHPIQDYSL
MNYIAYVTYTPLFIAGPIITFNDYVYQSKHTLPSINFKFIFYYAVRFVIALLSMEFIL
HFLHVVAISKTKAWENDTPFQISMIGLFNLNIIWLKLLIPWRLFRLWALLDGIDTPEN
MIRCVDNNYSSLAFWRAWHRSYNKWVVRYIYIPLGGSKNRVLTSLAVFSFVAIWHDIE
LKLLLWGWLIVLFLLPEIFATQIFSHYTDAVWYRHVCAVGAVFNIWVMMIANLFGFCL
GSDGTKKLLSDMFCTVSGFKFVILASVSLFIAVQIMFEIREEEKRHGIYLKC"
rep_origin 352695..352916
/note="ARS716;
Autonomously Replicating Sequence"
/db_xref="SGD:S000118456"
gene 353058..355472
/gene="SCY1"
/locus_tag="YGL083W"
/db_xref="GeneID:852797"
mRNA 353058..355472
/gene="SCY1"
/locus_tag="YGL083W"
/product="Scy1p"
/transcript_id="NM_001180948.1"
/db_xref="GI:296144962"
/db_xref="GeneID:852797"
CDS 353058..355472
/gene="SCY1"
/locus_tag="YGL083W"
/note="Putative kinase, suppressor of GTPase mutant,
similar to bovine rhodopsin kinase"
/codon_start=1
/product="Scy1p"
/protein_id="NP_011432.1"
/db_xref="GI:6321355"
/db_xref="SGD:S000003051"
/db_xref="GeneID:852797"
/translation="MMFWSSKTGITSKYSFSSSPTFTAEPWSIYTGRPKSSSSSSPSK
VSIFMFDKKQFENYLLHYGIIKSKSGSRDKVLIQEAYEILRNQANNLAKLKHPNILTL
IEPLEEHSKNFMFVTEFVTSSLETVFRETDDEEQNFLQGHVKDNIVVQRGILQLVNAL
DFVHNRASFVHLNIQPRAIFINENSDWKISGLGYLVKIPPGTNTSEYFLPQYDPRVPP
FMHLQLNYTAPEIVFENTLTFKNDYFSLGLLIYFLYTGKDLFRSENSTSEYKLEYNKF
ESKISTMSWDNIFSKVPQKLRHCIPKLINRDIYSRYDNITLILDSEFFQDPLVKTLNF
LDDLPTKNNEEKYVFLEGLVNLLPEFPPALLQKKFLPILLELLSQFCAEKVVSDKCVG
KSLDLIIKIGSTLSQLSFQEKVYPVLLSDANFPVLLKKATICLIDNLDTLKQKVKRSD
FLENILKPLFNYVLHDSESDITVVCQEKLLSQIPLALEVLDFPTVKQFLLPLLSNLFT
KTTSLTVKNTCVTCFQIMIEHKSIDSYTCSETVLPLFKSMKTRDPRILSKLLKLFETV
PLIITDEIVLVDQVLPLMWNYSMASTLTKSQYSGYTKAINKMSSDIQKHHIAKLDDKV
NDIGEDAFHKVIEPTIMKKEDPETVAAKNIEVAAMQPVKKKTGSSYGETLPQSKSILN
SKPLNPKNALATRGFPTRILNSPPQTPSSRTGSKVMTKGGSNDASSTKVEEEFNEFQS
FSSTGSIRQTSAPSDVWMNSTPSPTPTSASSTNLPPGFSISLQPNKRKDGSSDIPRSN
VYGSLI"
gene 355827..356972
/locus_tag="YGL082W"
/db_xref="GeneID:852798"
mRNA 355827..356972
/locus_tag="YGL082W"
/product="hypothetical protein"
/transcript_id="NM_001180947.3"
/db_xref="GI:398364582"
/db_xref="GeneID:852798"
CDS 355827..356972
/locus_tag="YGL082W"
/note="hypothetical protein; predicted
prenylation/proteolysis target of Afc1p and Rce1p; green
fluorescent protein (GFP)-fusion protein localizes to the
cytoplasm and nucleus; YGL082W is not an essential gene"
/codon_start=1
/product="hypothetical protein"
/protein_id="NP_011433.3"
/db_xref="GI:398364583"
/db_xref="SGD:S000003050"
/db_xref="GeneID:852798"
/translation="MDVTFLTKNVQINGTQFKILLQNGQGECALIALANVLLISPAHA
RYAQEISRLVRGKETVTLNELVQTLADMGVQNPNGTDVDKQQLLQILPQLYSGLNINP
EFNGSFEDGVEMSIFRLYNVGIVHGWIIDGDNDPNSYEHVSKYSYMGAQKVLVQSYEI
QKNNAQFENSEQIQSDAPYLKSFLARSATQLTEYGLTHLREILVERSYAVLFRNDHFC
TLYKNNGELFTLVTDPTYRNRKDINWQSLKSVNGSQDSYYTGNFIPTSLERTETTATG
QNESYISNPFSDQNTGHVTSNQVNSGASGVQQIEDDEELARRLQEQEDMRAANNMQNG
YANNGRNHQRERFERPEKNSKKNKFLPFNGSNKEKKRDKLKKNCVIM"
gene 357377..358339
/locus_tag="YGL081W"
/db_xref="GeneID:852799"
mRNA 357377..358339
/locus_tag="YGL081W"
/product="hypothetical protein"
/transcript_id="NM_001180946.1"
/db_xref="GI:296144964"
/db_xref="GeneID:852799"
CDS 357377..358339
/locus_tag="YGL081W"
/note="hypothetical protein; non-essential gene; interacts
genetically with CHS5, a gene involved in chitin
biosynthesis"
/codon_start=1
/product="hypothetical protein"
/protein_id="NP_011434.1"
/db_xref="GI:6321357"
/db_xref="SGD:S000003049"
/db_xref="GeneID:852799"
/translation="MGDIRTFVFAIEDTETTQGLCKTIGRSSSFDQNSLCKPYNLYFD
EPELSRQHAVLCIKTPIPKIEGVPSIEQLRICIRDLNNKTGTVNLVSDGPNDEIDLKN
GDAFGLIAIDNHPFRDNHHLAAKLIFRIELEYFDEAREIVKCTITNVTFGKNNTVSSF
PIHSATSTEDSDSSWYGLSEASTQTEVADECHETNTILTRGGRFSILSLRKRGSKQDQ
KICSNFDRKIHETSSFEEEIEVCTDTDTTEEKEEEEEKEEGDDEEGEIELEIIRVKRI
KGRTKIKKTLTCFSKNKKIITPQHSNSMWLLLIVILIFDRLLSN"
gene 358636..359028
/gene="FMP37"
/locus_tag="YGL080W"
/gene_synonym="MPC1"
/db_xref="GeneID:852800"
mRNA 358636..359028
/gene="FMP37"
/locus_tag="YGL080W"
/gene_synonym="MPC1"
/product="Fmp37p"
/transcript_id="NM_001180945.1"
/db_xref="GI:296144965"
/db_xref="GeneID:852800"
CDS 358636..359028
/gene="FMP37"
/locus_tag="YGL080W"
/gene_synonym="MPC1"
/note="Highly conserved subunit of the mitochondrial
pyruvate carrier; a mitochondrial inner membrane complex
comprised of Fmp37p/Mpc1p and either Mpc2p or Fmp43p/Mpc3p
mediates mitochondrial pyruvate uptake; null mutant
displays slow growth that is complemented by expression of
human or mouse ortholog; mutation in human ortholog is
associated with lactic acidosis and hyperpyruvatemia"
/codon_start=1
/product="Fmp37p"
/protein_id="NP_011435.1"
/db_xref="GI:6321358"
/db_xref="SGD:S000003048"
/db_xref="GeneID:852800"
/translation="MSQPVQRAAARSFLQKYINKETLKYIFTTHFWGPVSNFGIPIAA
IYDLKKDPTLISGPMTFALVTYSGVFMKYALSVSPKNYLLFGCHLINETAQLAQGYRF
LKYTYFTTDEEKKALDKEWKEKEKTGKQ"
gene 359444..360100
/gene="KXD1"
/locus_tag="YGL079W"
/db_xref="GeneID:852801"
mRNA 359444..360100
/gene="KXD1"
/locus_tag="YGL079W"
/product="Kxd1p"
/transcript_id="NM_001180944.1"
/db_xref="GI:296144966"
/db_xref="GeneID:852801"
CDS 359444..360100
/gene="KXD1"
/locus_tag="YGL079W"
/note="hypothetical protein; likely member of BLOC complex
involved in endosomal cargo sorting; null mutant is
sensitive to drug inducing secretion of vacuolar cargo;
GFP-fusion protein localizes to the endosome"
/codon_start=1
/product="Kxd1p"
/protein_id="NP_011436.1"
/db_xref="GI:6321359"
/db_xref="SGD:S000003047"
/db_xref="GeneID:852801"
/translation="MVTGISEENDDEETFSAVHSSTPSINSQSYAIPITEEMSSSFHD
SISTTSNSSGSFDSDGSNVSDVVEQNEMDNESNVDEDLFLDNDIPQSSNLLPTDAQDP
GPIFDVSRYIFDSLKQSIDSADFSEALSLQTKTSAVINSKSLELKQYIDEMKSRLTQL
QEKFENGEATSKKIKRDLETSRKNIDYLNAALRVDFPIEFNQAREKILERRLNEDHDC
"
gene complement(360288..361859)
/gene="DBP3"
/locus_tag="YGL078C"
/db_xref="GeneID:852802"
mRNA complement(360288..361859)
/gene="DBP3"
/locus_tag="YGL078C"
/product="RNA-dependent ATPase DBP3"
/transcript_id="NM_001180943.3"
/db_xref="GI:398364606"
/db_xref="GeneID:852802"
CDS complement(360288..361859)
/gene="DBP3"
/locus_tag="YGL078C"
/EC_number="3.6.1.-"
/note="RNA-Dependent ATPase, member of DExD/H-box family;
involved in cleavage of site A3 within the ITS1 spacer
during rRNA processing; not essential for growth, but
deletion causes severe slow-growth phenotype"
/codon_start=1
/product="RNA-dependent ATPase DBP3"
/protein_id="NP_011437.3"
/db_xref="GI:398364607"
/db_xref="SGD:S000003046"
/db_xref="GeneID:852802"
/translation="MTKEEIADKKRKVVDEEVIEKKKSKKHKKDKKDKKEKKDKKHKK
HKKEKKGEKEVEVPEKESEKKPEPTSAVASEFYVQSEALTSLPQSDIDEYFKENEIAV
EDSLDLALRPLLSFDYLSLDSSIQAEISKFPKPTPIQAVAWPYLLSGKDVVGVAETGS
GKTFAFGVPAISHLMNDQKKRGIQVLVISPTRELASQIYDNLIVLTDKVGMQCCCVYG
GVPKDEQRIQLKKSQVVVATPGRLLDLLQEGSVDLSQVNYLVLDEADRMLEKGFEEDI
KNIIRETDASKRQTLMFTATWPKEVRELASTFMNNPIKVSIGNTDQLTANKRITQIVE
VVDPRGKERKLLELLKKYHSGPKKNEKVLIFALYKKEAARVERNLKYNGYNVAAIHGD
LSQQQRTQALNEFKSGKSNLLLATDVAARGLDIPNVKTVINLTFPLTVEDYVHRIGRT
GRAGQTGTAHTLFTEQEKHLAGGLVNVLNGANQPVPEDLIKFGTHTKKKEHSAYGSFF
KDVDLTKKPKKITFD"
gene complement(362225..363916)
/gene="HNM1"
/locus_tag="YGL077C"
/gene_synonym="CTR1"
/db_xref="GeneID:852803"
mRNA complement(362225..363916)
/gene="HNM1"
/locus_tag="YGL077C"
/gene_synonym="CTR1"
/product="Hnm1p"
/transcript_id="NM_001180942.1"
/db_xref="GI:296144968"
/db_xref="GeneID:852803"
CDS complement(362225..363916)
/gene="HNM1"
/locus_tag="YGL077C"
/gene_synonym="CTR1"
/note="Choline/ethanolamine transporter; involved in the
uptake of nitrogen mustard and the uptake of glycine
betaine during hypersaline stress; co-regulated with
phospholipid biosynthetic genes and negatively regulated
by choline and myo-inositol"
/codon_start=1
/product="Hnm1p"
/protein_id="NP_011438.1"
/db_xref="GI:6321361"
/db_xref="SGD:S000003045"
/db_xref="GeneID:852803"
/translation="MSIRNDNASGGYMQPDQSSNASMHKRDLRVEEEIKPLDDMDSKG
AVAADGEVHLRKSFSLWSILGVGFGLTNSWFGISTSMVAGISSGGPMMIVYGIIIVAL
ISICIGTSLGELSSAYPHAGGQFWWSLKLAPPKYKRFAAYMCGSFAYAGSVFTSASTT
LSVATEVVGMYALTHPEFIPKRWHIFVCFELLHLFLMFFNCYGKSLPIISSSSLYISL
LSFFTITITVLACSHGKFNDAKFVFATFNNETGWKNGGIAFIVGLINPAWSFSCLDCA
THMAFEVEKPERVIPIAIMGTVAIGFVTSFCYVIAMFFSIQDLDAVLSSTTGAPILDI
YNQALGNKSGAIFLGCLILFTSFGCVIACHTWQARLCWSFARDNGLPLSRLWSQVNPH
TGVPLNAHLMSCAWITLIGLLYLASSTAFQSLITGCIAFLLLSYIIPVICLLAKKRNI
AHGPFWLGKFGFFSNIVLLGWTVFSVVFFSFPPVLPVTKDNMNYVCVVIVGYTAYSIL
YWKYKGKKEFHALEESENEQAEYSNNFDTIEDSREFSVAASDVELENEHVPWGKK"
gene complement(364335..365996)
/gene="RPL7A"
/locus_tag="YGL076C"
/db_xref="GeneID:852804"
mRNA complement(join(364335..364964,365433..365526,
365986..365996))
/gene="RPL7A"
/locus_tag="YGL076C"
/product="ribosomal 60S subunit protein L7A"
/transcript_id="NM_001180941.1"
/db_xref="GI:296144969"
/db_xref="GeneID:852804"
CDS complement(join(364335..364964,365433..365526,
365986..365996))
/gene="RPL7A"
/locus_tag="YGL076C"
/note="Ribosomal 60S subunit protein L7A; contains a
conserved C-terminal Nucleic acid Binding Domain (NDB2);
homologous to mammalian ribosomal protein L7 and bacterial
L30; RPL7A has a paralog, RPL7B, that arose from the whole
genome duplication"
/codon_start=1
/product="ribosomal 60S subunit protein L7A"
/protein_id="NP_011439.1"
/db_xref="GI:6321362"
/db_xref="SGD:S000003044"
/db_xref="GeneID:852804"
/translation="MAAEKILTPESQLKKSKAQQKTAEQVAAERAARKAANKEKRAII
LERNAAYQKEYETAERNIIQAKRDAKAAGSYYVEAQHKLVFVVRIKGINKIPPKPRKV
LQLLRLTRINSGTFVKVTKATLELLKLIEPYVAYGYPSYSTIRQLVYKRGFGKINKQR
VPLSDNAIIEANLGKYGILSIDDLIHEIITVGPHFKQANNFLWPFKLSNPSGGWGVPR
KFKHFIQGGSFGNREEFINKLVKSMN"
gene complement(365163..365251)
/locus_tag="snR39"
/db_xref="GeneID:9164895"
ncRNA complement(365163..365251)
/locus_tag="snR39"
/ncRNA_class="snoRNA"
/product="SNR39"
/note="C/D box small nucleolar RNA (snoRNA), guides
2'-O-methylation of large subunit (LSU) rRNA at position
A807"
/db_xref="SGD:S000007302"
/db_xref="GeneID:9164895"
gene complement(366374..366469)
/locus_tag="snR39B"
/db_xref="GeneID:9164896"
ncRNA complement(366374..366469)
/locus_tag="snR39B"
/ncRNA_class="snoRNA"
/product="SNR39B"
/note="C/D box small nucleolar RNA (snoRNA), guides
2'-O-methylation of large subunit (LSU) rRNA at position
G805"
/db_xref="SGD:S000007303"
/db_xref="GeneID:9164896"
gene complement(366925..368088)
/gene="MPS2"
/locus_tag="YGL075C"
/gene_synonym="MMC1"
/db_xref="GeneID:852805"
mRNA complement(366925..368088)
/gene="MPS2"
/locus_tag="YGL075C"
/gene_synonym="MMC1"
/product="Mps2p"
/transcript_id="NM_001180940.1"
/db_xref="GI:296144970"
/db_xref="GeneID:852805"
CDS complement(366925..368088)
/gene="MPS2"
/locus_tag="YGL075C"
/gene_synonym="MMC1"
/note="Essential membrane protein localized at the nuclear
envelope and spindle pole body (SPB), required for
insertion of the newly duplicated SPB into the nuclear
envelope; potentially phosphorylated by Cdc28p"
/codon_start=1
/product="Mps2p"
/protein_id="NP_011440.1"
/db_xref="GI:6321363"
/db_xref="SGD:S000003043"
/db_xref="GeneID:852805"
/translation="MSNGAFDAIFEYAWGQIDKPISGDFIYGKDLPKLIEIIENIFQK
AQKSGSYELRLPLFSEINKDLFRTFSNTKTFFKIHKEEFDDIFFNLVNHPLREILENA
FIGVDSIPSDFIVSMNLNSPSKFLVENKNKNTEGAGISTPRKKLTESPIKLLSRNNIG
KALEVQVEELKRELTAKQSLLQENERQVSELKIRLETYQEKYASIQQRFSDLQKARQV
EDNQNSSRTSDPGSPLVTGIDQKAILEEFRRRLQRQTDTISFLKDQIRRERGLNCSND
KVSHSKRKHATTDGDGTFKNFISAVPSNIWVKATIRIIVCFALLAGVLPYIRKYVYAH
DTPSQNSRLQLSWWENSGILSKIVWFFEDQTDLETEYRSNANVDDAYSRVFGI"
gene 368753..371254
/gene="HSF1"
/locus_tag="YGL073W"
/gene_synonym="EXA3; MAS3"
/db_xref="GeneID:852806"
mRNA 368753..371254
/gene="HSF1"
/locus_tag="YGL073W"
/gene_synonym="EXA3; MAS3"
/product="Hsf1p"
/transcript_id="NM_001180938.3"
/db_xref="GI:398364622"
/db_xref="GeneID:852806"
CDS 368753..371254
/gene="HSF1"
/locus_tag="YGL073W"
/gene_synonym="EXA3; MAS3"
/note="Trimeric heat shock transcription factor, activates
multiple genes in response to stresses that include
hyperthermia; recognizes variable heat shock elements
(HSEs) consisting of inverted NGAAN repeats;
posttranslationally regulated"
/codon_start=1
/product="Hsf1p"
/protein_id="NP_011442.3"
/db_xref="GI:398364623"
/db_xref="SGD:S000003041"
/db_xref="GeneID:852806"
/translation="MNNAANTGTTNESNVSDAPRIEPLPSLNDDDIEKILQPNDIFTT
DRTDASTTSSTAIEDIINPSLDPQSAASPVPSSSFFHDSRKPSTSTHLVRRGTPLGIY
QTNLYGHNSRENTNPNSTLLSSKLLAHPPVPYGQNPDLLQHAVYRAQPSSGTTNAQPR
QTTRRYQSHKSRPAFVNKLWSMLNDDSNTKLIQWAEDGKSFIVTNREEFVHQILPKYF
KHSNFASFVRQLNMYGWHKVQDVKSGSIQSSSDDKWQFENENFIRGREDLLEKIIRQK
GSSNNHNSPSGNGNPANGSNIPLDNAAGSNNSNNNISSSNSFFNNGHLLQGKTLRLMN
EANLGDKNDVTAILGELEQIKYNQIAISKDLLRINKDNELLWQENMMARERHRTQQQA
LEKMFRFLTSIVPHLDPKMIMDGLGDPKVNNEKLNSANNIGLNRDNTGTIDELKSNDS
FINDDRNSFTNATTNARNNMSPNNDDNSIDTASTNTTNRKKNIDENIKNNNDIINDII
FNTNLANNLSNYNSNNNAGSPIRPYKQRYLLKNRANSSTSSENPSLTPFDIESNNDRK
ISEIPFDDEEEEETDFRPFTSRDPNNQTSENTFDPNRFTMLSDDDLKKDSHTNDNKHN
ESDLFWDNVHRNIDEQDARLQNLENMVHILSPGYPNKSFNNKTSSTNTNSNMESAVNV
NSPGFNLQDYLTGESNSPNSVHSVPSNGSGSTPLPMPNDNDTEHASTSVNQGENGSGL
TPFLTVDDHTLNDNNTSEGSTRVSPDIKFSATENTKVSDNLPSFNDHSYSTQADTAPE
NAKKRFVEEIPEPAIVEIQDPTEYNDHRLPKRAKK"
gene 372012..374084
/gene="AFT1"
/locus_tag="YGL071W"
/gene_synonym="RCS1"
/db_xref="GeneID:852809"
mRNA 372012..374084
/gene="AFT1"
/locus_tag="YGL071W"
/gene_synonym="RCS1"
/product="Aft1p"
/transcript_id="NM_001180936.1"
/db_xref="GI:296144972"
/db_xref="GeneID:852809"
CDS 372012..374084
/gene="AFT1"
/locus_tag="YGL071W"
/gene_synonym="RCS1"
/note="Transcription factor involved in iron utilization
and homeostasis; binds consensus site PyPuCACCCPu and
activates transcription in response to changes in iron
availability; in iron-replete conditions activity is
negatively regulated by Grx3p, Grx4p, and Fra2p, which
regulate Aft1p translocation from the nucleus to the
cytoplasm; AFT1 has a paralog, AFT2, that arose from the
whole genome duplication; relative distribution to the
nucleus increases upon DNA replication stress"
/codon_start=1
/product="Aft1p"
/protein_id="NP_011444.1"
/db_xref="GI:6321367"
/db_xref="SGD:S000003039"
/db_xref="GeneID:852809"
/translation="MEGFNPADIEHASPINSSDSHSSSFVYALPKSASEYVVNHNEGR
ASASGNPAAVPSPIMTLNLKSTHSLNIDQHVHTSTSPTETIGHIHHVEKLNQNNLIHL
DPVPNFEDKSDIKPWLQKIFYPQGIELVIERSDAFKVVFKCKAAKRGRNARRKRKDKP
KGQDHEDEKSKINDDELEYASPSNATVTNGPQTSPDQTSSIKPKKKRCVSRFNNCPFR
VRATYSLKRKRWSIVVMDNNHSHQLKFNPDSEEYKKFKEKLRKDNDVDAIKKFDELEY
RTLANLPIPTATIPCDCGLTNEIQSFNVVLPTNSNVTSSASSSTVSSISLDSSNASKR
PCLPSVNNTGSINTNNVRKPKSQCKNKDTLLKRTTMQNFLTTKSRLRKTGTPTSSQHS
STAFSGYIDDPFNLNEILPLPASDFKLNTVTNLNEIDFTNIFTKSPHPHSGSTHPRQV
FDQLDDCSSILFSPLTTNTNNEFEGESDDFVHSPYLNSEADFSQILSSAPPVHHDPNE
THQENQDIIDRFANSSQEHNEYILQYLTHSDAANHNNIGVPNNNSHSLNTQHNVSDLG
NSLLRQEALVGSSSTKIFDELKFVQNGPHGSQHPIDFQHVDHRHLSSNEPQVRSHQYG
PQQQPPQQLQYHQNQPHDGHNHEQHQTVQKDMQTHESLEIMGNTLLEEFKDIKMVNGE
LKYVKPED"
gene complement(374459..374827)
/gene="RPB9"
/locus_tag="YGL070C"
/gene_synonym="SSU73"
/db_xref="GeneID:852810"
mRNA complement(374459..374827)
/gene="RPB9"
/locus_tag="YGL070C"
/gene_synonym="SSU73"
/product="Rpb9p"
/transcript_id="NM_001180935.1"
/db_xref="GI:296144973"
/db_xref="GeneID:852810"
CDS complement(374459..374827)
/gene="RPB9"
/locus_tag="YGL070C"
/gene_synonym="SSU73"
/note="RNA polymerase II subunit B12.6; contacts DNA;
mutations affect transcription start site selection and
fidelity of transcription"
/codon_start=1
/product="Rpb9p"
/protein_id="NP_011445.1"
/db_xref="GI:6321368"
/db_xref="SGD:S000003038"
/db_xref="GeneID:852810"
/translation="MTTFRFCRDCNNMLYPREDKENNRLLFECRTCSYVEEAGSPLVY
RHELITNIGETAGVVQDIGSDPTLPRSDRECPKCHSRENVFFQSQQRRKDTSMVLFFV
CLSCSHIFTSDQKNKRTQFS"
gene 375087..375671
/gene="MNP1"
/locus_tag="YGL068W"
/db_xref="GeneID:852811"
mRNA 375087..375671
/gene="MNP1"
/locus_tag="YGL068W"
/product="mitochondrial nucleoid protein MNP1"
/transcript_id="NM_001180933.1"
/db_xref="GI:296144974"
/db_xref="GeneID:852811"
CDS 375087..375671
/gene="MNP1"
/locus_tag="YGL068W"
/note="Protein associated with the mitochondrial nucleoid;
putative mitochondrial ribosomal protein with similarity
to E. coli L7/L12 ribosomal protein; required for normal
respiratory growth"
/codon_start=1
/product="mitochondrial nucleoid protein MNP1"
/protein_id="NP_011447.1"
/db_xref="GI:6321369"
/db_xref="SGD:S000003036"
/db_xref="GeneID:852811"
/translation="MSLRILAKRSSSIWMKTRVTPALISPITITTRFNSTTTTAPSHK
DDVRPVDPKISKIVQDISQLTLLETSSLINELKTVLNIPEISMPMGGFMAGAAGAGAG
NVPSSTGEAGSGAEEEAKPEAKTVFTVKLDSFDTKTKAKVIKEVKGLLGLSLVEAKKF
VEAAPKVLKENVAKDDAEKIKKTLEDLGAKVSLE"
gene 376101..377255
/gene="NPY1"
/locus_tag="YGL067W"
/db_xref="GeneID:852813"
mRNA 376101..377255
/gene="NPY1"
/locus_tag="YGL067W"
/product="NAD(+) diphosphatase"
/transcript_id="NM_001180932.3"
/db_xref="GI:398364648"
/db_xref="GeneID:852813"
CDS 376101..377255
/gene="NPY1"
/locus_tag="YGL067W"
/EC_number="3.6.1.22"
/note="NADH diphosphatase (pyrophosphatase), hydrolyzes
the pyrophosphate linkage in NADH and related nucleotides;
localizes to peroxisomes"
/codon_start=1
/product="NAD(+) diphosphatase"
/protein_id="NP_011448.3"
/db_xref="GI:398364649"
/db_xref="SGD:S000003035"
/db_xref="GeneID:852813"
/translation="MSTAVTFFGQHVLNRVSFLRCSKEFIKKSLNHDSTVFIPFIEGE
ALISPENGDLVQLSNSVKSYKNILSAIVPLYTTLLNTTRSRSDESGINVTFLGLLEGT
DSAFNFEWSNISYKGTPYFGLDIRVTESTLFKKVDFEPIFSYPKVTRDHIFKQTNEDA
SLYSQGKMYLDWLAKYKFCPGCGSPLFPVEAGTKLQCSNENRNVYCNVRDARINNVCF
PRTDPTVIIALTNSDYSKCCLARSKKRYGDFVLYSTIAGFMEPSETIEEACIREIWEE
TGISCKNIDIVRSQPWPYPCSLMIGCLGIVQFNSKNEVINLNHDDELLDAQWFDTTEI
IQALDKYAGGYRVPFKNDINLPGSTTIAFQLINHVCENYKNLRKTSSSHL"
gene 377609..379582
/gene="SGF73"
/locus_tag="YGL066W"
/gene_synonym="SCA7"
/db_xref="GeneID:852814"
mRNA 377609..379582
/gene="SGF73"
/locus_tag="YGL066W"
/gene_synonym="SCA7"
/product="Sgf73p"
/transcript_id="NM_001180931.1"
/db_xref="GI:296144976"
/db_xref="GeneID:852814"
CDS 377609..379582
/gene="SGF73"
/locus_tag="YGL066W"
/gene_synonym="SCA7"
/note="SAGA complex subunit; has a role in anchoring the
deubiquitination module into SAGA and SLIK complexes;
involved in preinitiation complex assembly at promoters;
human ortholog ataxin-7 is associated with spinocerebellar
ataxia diseases; mutant displays reduced transcription
elongation in the G-less-based run-on (GLRO) assay"
/codon_start=1
/product="Sgf73p"
/protein_id="NP_011449.1"
/db_xref="GI:6321372"
/db_xref="SGD:S000003034"
/db_xref="GeneID:852814"
/translation="MRSGDAEIKGIKPKVIEEYSLSQGSGPSNDSWKSLMSSAKDTPL
QYDHMNRESLKKYFNPNAQLIEDPLDKPIQYRVCEKCGKPLALTAIVDHLENHCAGAS
GKSSTDPRDESTRETIRNGVESTGRNNNDDDNSNDNNNDDDDDDDNDDNEDDDDADDD
DDNSNGANYKKNDSSFNPLKRSTSMESANTPNMDTKRSKTGTPQTFSSSIKKQKKVKQ
RNPTEKHLIDFNKQCGVELPEGGYCARSLTCKSHSMGAKRAVSGRSKPYDVLLADYHR
EHQTKIGAAAEKRAKQQELQKLQKQIQKEQKKHTQQQKQGQRSKQRNVNGGKSAKNGG
KSTVHNGNNINEIGHVNLTPEEETTQVLNGVSRSFPLPLESTVLSSVRYRTKYFRMRE
MFASSFSVKPGYTSPGYGAIHSRVGCLDLDRTTDYKFRVRTPQPINHLTNQNLNPKQI
QRLQQQRALQAQLLSQQQQQQQQQQQHHSPQAQAQASTQQPTQGMVPNHFPGGATNSS
FNANVSSKQIQQQQQQQQHKSQDTGLTPLEIQSQQQKLRQQQLQQQKFEAAASYLANA
TKLMQESNQDSHLSGTHNNNSSKNGNNNLMTMKASISSPNTSVNSIQSPPSVNSVNGS
GQGVSTGINVSGNNGRIEVGIGNSVNPYNGRIN"
gene complement(379760..381271)
/gene="ALG2"
/locus_tag="YGL065C"
/db_xref="GeneID:852815"
mRNA complement(379760..381271)
/gene="ALG2"
/locus_tag="YGL065C"
/product="GDP-Man:Man(1)GlcNAc(2)-PP-dolichol
alpha-1,3-mannosyltransferase"
/transcript_id="NM_001180930.1"
/db_xref="GI:296144977"
/db_xref="GeneID:852815"
CDS complement(379760..381271)
/gene="ALG2"
/locus_tag="YGL065C"
/EC_number="2.4.1.132"
/EC_number="2.4.1.-"
/note="Mannosyltransferase that catalyzes two consecutive
steps in the N-linked glycosylation pathway; alg2 mutants
exhibit temperature-sensitive growth and abnormal
accumulation of the lipid-linked oligosaccharide
Man2GlcNAc2-PP-Dol"
/codon_start=1
/product="GDP-Man:Man(1)GlcNAc(2)-PP-dolichol
alpha-1,3-mannosyltransferase"
/protein_id="NP_011450.1"
/db_xref="GI:6321373"
/db_xref="SGD:S000003033"
/db_xref="GeneID:852815"
/translation="MIEKDKRTIAFIHPDLGIGGAERLVVDAALGLQQQGHSVIIYTS
HCDKSHCFEEVKNGQLKVEVYGDFLPTNFLGRFFIVFATIRQLYLVIQLILQKKVNAY
QLIIIDQLSTCIPLLHIFSSATLMFYCHFPDQLLAQRAGLLKKIYRLPFDLIEQFSVS
AADTVVVNSNFTKNTFHQTFKYLSNDPDVIYPCVDLSTIEIEDIDKKFFKTVFNEGDR
FYLSINRFEKKKDVALAIKAFALSEDQINDNVKLVICGGYDERVAENVEYLKELQSLA
DEYELSHTTIYYQEIKRVSDLESFKTNNSKIIFLTSISSSLKELLLERTEMLLYTPAY
EHFGIVPLEAMKLGKPVLAVNNGGPLETIKSYVAGENESSATGWLKPAVPIQWATAID
ESRKILQNGSVNFERNGPLRVKKYFSREAMTQSFEENVEKVIWKEKKYYPWEIFGISF
SNFILHMAFIKILPNNPWPFLFMATFMVLYFKNYLWGIYWAFVFALSYPYEEI"
gene complement(381523..383208)
/gene="MRH4"
/locus_tag="YGL064C"
/db_xref="GeneID:852816"
mRNA complement(381523..383208)
/gene="MRH4"
/locus_tag="YGL064C"
/product="Mrh4p"
/transcript_id="NM_001180929.1"
/db_xref="GI:296144978"
/db_xref="GeneID:852816"
CDS complement(381523..383208)
/gene="MRH4"
/locus_tag="YGL064C"
/EC_number="3.6.1.-"
/note="Mitochondrial ATP-dependent RNA helicase of the
DEAD-box family, plays an essential role in mitochondrial
function"
/codon_start=1
/product="Mrh4p"
/protein_id="NP_011451.1"
/db_xref="GI:6321374"
/db_xref="SGD:S000003032"
/db_xref="GeneID:852816"
/translation="MSLFFKPVISPQWSFPVLLKIGVRSYAGGPRTKHKGNSPLASVP
TGSSNKNRKQKAKGKKGNKKNDPDQAFNFGEYGGLKKDVEMNMDSTNKLIQKISNFDQ
LLILPPVRDAVKEIISKESLKLQDSRKKTSENIIPSPIQTVAIKRISKNLMDPKLQIH
AIAAETGSGKTMAYLIPLIDYLKRQELETPELWETLRKNVLIRSIILVPTHELVDQVY
ETVSKTKTLLGLNSFKWDKATSYRDLLENIKNRIDILVTTPGKLLNLFSIRMITRPDK
VLSKVGFVVLDEADTLLDRSWLEETHSAIKRIPNINHLIFCSATIPQEFNKTMQRLFP
TVVPIMTPRLHKLPFALDFKVINSALSPFKGSKIKALAQTLYAISNDDTEPGFEKRCI
IFVNEKKNVPEIVNLLNKKFGHNAIGLTGEDTFEERSEKIMPFLSPPRPLSEVVAQST
SPPTSLKKFEIPDSNIVIGKLKNTNSNGTAPSNKSLHVLVTTDLMARGLNFKGVRNVV
LYDVPKTSIDLIHRVGRTARMKQGGRVFMLTDSKTKSWAKALPKIIKKHQRLS"
gene 383654..384766
/gene="PUS2"
/locus_tag="YGL063W"
/db_xref="GeneID:852817"
mRNA 383654..384766
/gene="PUS2"
/locus_tag="YGL063W"
/product="pseudouridine synthase PUS2"
/transcript_id="NM_001180928.4"
/db_xref="GI:398364672"
/db_xref="GeneID:852817"
CDS 383654..384766
/gene="PUS2"
/locus_tag="YGL063W"
/EC_number="4.2.1.70"
/note="Mitochondrial tRNA:pseudouridine synthase; acts at
positions 27 and 28, but not at position 72; efficiently
and rapidly targeted to mitochondria, specifically
dedicated to mitochondrial tRNA modification"
/codon_start=1
/product="pseudouridine synthase PUS2"
/protein_id="NP_011452.4"
/db_xref="GI:398364673"
/db_xref="SGD:S000003031"
/db_xref="GeneID:852817"
/translation="MLLGYCGSGYYGMQYNPPHKTIEGEILTKLFDVGAISEENSLAP
KKNSFMAAARTDKGVHAMLNLLSLKITLREDTVAKLNAALPPEIRVWGIQPVNKKFNA
RSACDSRWYQYLIPEFILIGPPRSSLLHRNVGGCYREDGSQEVWDTFLEQTRGRFSGD
ELCRLQDTAQKLSESDPLVQDYVGLLSGTLSGYCLSPSKLDAFEAAMQEYVGTHNFHN
FTTGKLWGDPSAQRHIKKVVVSQASPGWICVRIHGQSFMLHQIRRMVALAVLAARCQL
PPNIVRNYFNAGPRKYIPRAPAQGLLLEGPVFDGYNTKLRNLLYCEIRPDDITLERMC
RFRERQICTAIAHEETQRHVFCHFVRQMNRLATPLI"
gene 385196..388732
/gene="PYC1"
/locus_tag="YGL062W"
/db_xref="GeneID:852818"
mRNA 385196..388732
/gene="PYC1"
/locus_tag="YGL062W"
/product="pyruvate carboxylase 1"
/transcript_id="NM_001180927.1"
/db_xref="GI:296144980"
/db_xref="GeneID:852818"
CDS 385196..388732
/gene="PYC1"
/locus_tag="YGL062W"
/EC_number="6.4.1.1"
/note="Pyruvate carboxylase isoform, cytoplasmic enzyme
that converts pyruvate to oxaloacetate; highly similar to
isoform Pyc2p but differentially regulated; mutations in
the human homolog are associated with lactic acidosis"
/codon_start=1
/product="pyruvate carboxylase 1"
/protein_id="NP_011453.1"
/db_xref="GI:6321376"
/db_xref="SGD:S000003030"
/db_xref="GeneID:852818"
/translation="MSQRKFAGLRDNFNLLGEKNKILVANRGEIPIRIFRTAHELSMQ
TVAIYSHEDRLSTHKQKADEAYVIGEVGQYTPVGAYLAIDEIISIAQKHQVDFIHPGY
GFLSENSEFADKVVKAGITWIGPPAEVIDSVGDKVSARNLAAKANVPTVPGTPGPIET
VEEALDFVNEYGYPVIIKAAFGGGGRGMRVVREGDDVADAFQRATSEARTAFGNGTCF
VERFLDKPKHIEVQLLADNHGNVVHLFERDCSVQRRHQKVVEVAPAKTLPREVRDAIL
TDAVKLAKECGYRNAGTAEFLVDNQNRHYFIEINPRIQVEHTITEEITGIDIVAAQIQ
IAAGASLPQLGLFQDKITTRGFAIQCRITTEDPAKNFQPDTGRIEVYRSAGGNGVRLD
GGNAYAGTIISPHYDSMLVKCSCSGSTYEIVRRKMIRALIEFRIRGVKTNIPFLLTLL
TNPVFIEGTYWTTFIDDTPQLFQMVSSQNRAQKLLHYLADVAVNGSSIKGQIGLPKLK
SNPSVPHLHDAQGNVINVTKSAPPSGWRQVLLEKGPAEFARQVRQFNGTLLMDTTWRD
AHQSLLATRVRTHDLATIAPTTAHALAGRFALECWGGATFDVAMRFLHEDPWERLRKL
RSLVPNIPFQMLLRGANGVAYSSLPDNAIDHFVKQAKDNGVDIFRVFDALNDLEQLKV
GVDAVKKAGGVVEATVCFSGDMLQPGKKYNLDYYLEIAEKIVQMGTHILGIKDMAGTM
KPAAAKLLIGSLRAKYPDLPIHVHTHDSAGTAVASMTACALAGADVVDVAINSMSGLT
SQPSINALLASLEGNIDTGINVEHVRELDAYWAEMRLLYSCFEADLKGPDPEVYQHEI
PGGQLTNLLFQAQQLGLGEQWAETKRAYREANYLLGDIVKVTPTSKVVGDLAQFMVSN
KLTSDDVRRLANSLDFPDSVMDFFEGLIGQPYGGFPEPFRSDVLRNKRRKLTCRPGLE
LEPFDLEKIREDLQNRFGDVDECDVASYNMYPRVYEDFQKMRETYGDLSVLPTRSFLS
PLETDEEIEVVIEQGKTLIIKLQAVGDLNKKTGEREVYFDLNGEMRKIRVADRSQKVE
TVTKSKADMHDPLHIGAPMAGVIVEVKVHKGSLIKKGQPVAVLSAMKMEMIISSPSDG
QVKEVFVSDGENVDSSDLLVLLEDQVPVETKA"
rep_origin 388658..388891
/note="ARS717;
Autonomously Replicating Sequence"
/db_xref="SGD:S000118457"
gene complement(388968..389711)
/gene="DUO1"
/locus_tag="YGL061C"
/db_xref="GeneID:852819"
mRNA complement(388968..389711)
/gene="DUO1"
/locus_tag="YGL061C"
/product="Duo1p"
/transcript_id="NM_001180926.1"
/db_xref="GI:296144981"
/db_xref="GeneID:852819"
CDS complement(388968..389711)
/gene="DUO1"
/locus_tag="YGL061C"
/note="Essential subunit of the Dam1 complex (aka DASH
complex), couples kinetochores to the force produced by MT
depolymerization thereby aiding in chromosome segregation;
is transferred to the kinetochore prior to mitosis"
/codon_start=1
/product="Duo1p"
/protein_id="NP_011454.1"
/db_xref="GI:6321377"
/db_xref="SGD:S000003029"
/db_xref="GeneID:852819"
/translation="MSEQSQLDDSTIDKLIPQIFNEMRSNLNNTTNKFPKSTGGGASD
NISANSNSIRSFNSITTQSLLKESESLDKITAMIKNVTAALKNNLPVYVNQVHEVCKS
TNSILDSWINIHSQAGYIHKLMSDQTYLKLINDRLHNENVNTNDEDGSTLHNVIALKK
KEILDLRQKLENRKGEKDAAPAKPPNQGLNPRYGVQSGRRPVPSAGISNNGRVRKTHV
PASKRPSGIPRVTNRWTKPTASSSRKMFR"
gene 390065..391990
/gene="YBP2"
/locus_tag="YGL060W"
/gene_synonym="YBH1"
/db_xref="GeneID:852820"
mRNA 390065..391990
/gene="YBP2"
/locus_tag="YGL060W"
/gene_synonym="YBH1"
/product="Ybp2p"
/transcript_id="NM_001180925.1"
/db_xref="GI:296144982"
/db_xref="GeneID:852820"
CDS 390065..391990
/gene="YBP2"
/locus_tag="YGL060W"
/gene_synonym="YBH1"
/note="Central kinetochore associated protein that
mediates mitotic progression; interacts with several
central kinetochore proteins and the centromeric histone
Cse4p; role in resistance to oxidative stress; similarity
to Ybp1p and Slk19p"
/codon_start=1
/product="Ybp2p"
/protein_id="NP_011455.1"
/db_xref="GI:6321378"
/db_xref="SGD:S000003028"
/db_xref="GeneID:852820"
/translation="MYNEQVNSGKSIKEKERYLDALLKILKDNPVTLKEIGWDLPKGL
LQFFSRKNINVNIHLVFSPLVSSVMECFNELAINGNPKECLLTACELVSTLHIVLTET
GDSDEENEDLNDSNRNDASNITDELSVITPEIGHYMAKNTVEFIPNLKIYVLFEFMSL
LLKRVDTLYPSKFLAMVTSAIIKYVTTNVQAMDDPHFILRIVYNFCTNYSPAQPSASL
TDGISTNDLEKIHDDESALQKKLLANLSVFVISNCLKNHPGNIDKIYFKTLMHKKTDE
NEIDASVLQICHQYYEYVTSLDVHMKELLEKCLVESRSIYNSLLMNPAASTPEFKEEI
NQLVYEVSYAYQIKKLADEKNLELDQYGVVILSAIHYSKNGTHLLPQIDIQSAIYLYL
RCTTASLFSEIYENKFLESSVRYWLWVSTTETSTEKIKCALQELPGHITTAFLQMLLM
KTCNESNNDTKLTEITLLRRLLYLMPESTSFTFIFETLLHCPYITAKIAVLDILRDMM
IRSPEAANRDETVGLIEQQNPGNTANSVPIMPTLPPRPYITINEDRMASIHSIALICF
SAAKQKKRTQGDLLLVLTYMKFFVSLRNKWDLGLLTLINKEISESFQGEGEPELAFIN
ISNNTLGEYIEEMNIRS"
gene 392223..393698
/gene="PKP2"
/locus_tag="YGL059W"
/db_xref="GeneID:852821"
mRNA 392223..393698
/gene="PKP2"
/locus_tag="YGL059W"
/product="Pkp2p"
/transcript_id="NM_001180924.4"
/db_xref="GI:398364690"
/db_xref="GeneID:852821"
CDS 392223..393698
/gene="PKP2"
/locus_tag="YGL059W"
/EC_number="2.7.11.-"
/note="Mitochondrial protein kinase; negatively regulates
activity of the pyruvate dehydrogenase complex by
phosphorylating the ser-133 residue of the Pda1p subunit;
acts in concert with kinase Pkp1p and phosphatases Ptc5p
and Ptc6p; relocalizes from mitochondrion to cytoplasm
upon DNA replication stress"
/codon_start=1
/product="Pkp2p"
/protein_id="NP_011456.5"
/db_xref="GI:398364691"
/db_xref="SGD:S000003027"
/db_xref="GeneID:852821"
/translation="MSKYQINCIRYRHFLRTSNISQIPDFTKYCIGPVNEELAPYIME
TMKAYPSNSEYINPQHYYHNRTVLVENYLKRSPNPVSLTQLAQYYDDSTKLTRTKIIN
SGKFVKEELVIRIAHKLNQLQQLPFNVVNNFHFVQVYESYYNIFESFRKYPTIRTLED
ASQFADFIKNMLEGFNTLNLPHLIMGALECTILDLYPREKMDQLLSDLLRARISRRLI
VEEHVSITANYTSGKEENTLVLGDIFQECSAKKYLLEASEESQKFIQDMYFKDIPMPE
FIIEGDTQLSFYFLPTHLKYLLGEILRNTYEATMKHYIRKGLEKPEPIIVTVVSNDES
YLFRISDKAGGVLHDDENLWSFGKSKERAQESLNNFHKLPGLQTVSIYDEVHSHTKYN
SKLKSLQSITLKPYMHTSLEPMSYPSIINGHIKYETPLIELLKRSFRYKLGIGLAMCK
VYAEYWNGDLSLHSMPGYGTDVVLKLGNLMKHTKKLQLDKV"
gene 393986..394504
/gene="RAD6"
/locus_tag="YGL058W"
/gene_synonym="PSO8; UBC2"
/db_xref="GeneID:852822"
mRNA 393986..394504
/gene="RAD6"
/locus_tag="YGL058W"
/gene_synonym="PSO8; UBC2"
/product="E2 ubiquitin-conjugating protein RAD6"
/transcript_id="NM_001180923.1"
/db_xref="GI:296144984"
/db_xref="GeneID:852822"
CDS 393986..394504
/gene="RAD6"
/locus_tag="YGL058W"
/gene_synonym="PSO8; UBC2"
/EC_number="6.3.2.19"
/note="Ubiquitin-conjugating enzyme (E2), involved in
postreplication repair (as a heterodimer with Rad18p),
DSBR and checkpoint control (as a heterodimer with Bre1p),
ubiquitin-mediated N-end rule protein degradation (as a
heterodimer with Ubr1p"
/codon_start=1
/product="E2 ubiquitin-conjugating protein RAD6"
/protein_id="NP_011457.1"
/db_xref="GI:6321380"
/db_xref="SGD:S000003026"
/db_xref="GeneID:852822"
/translation="MSTPARRRLMRDFKRMKEDAPPGVSASPLPDNVMVWNAMIIGPA
DTPYEDGTFRLLLEFDEEYPNKPPHVKFLSEMFHPNVYANGEICLDILQNRWTPTYDV
ASILTSIQSLFNDPNPASPANVEAATLFKDHKSQYVKRVKETVEKSWEDDMDDMDDDD
DDDDDDDDDEAD"
gene complement(394966..395829)
/gene="GEP7"
/locus_tag="YGL057C"
/db_xref="GeneID:852823"
mRNA complement(394966..395829)
/gene="GEP7"
/locus_tag="YGL057C"
/product="Gep7p"
/transcript_id="NM_001180922.1"
/db_xref="GI:296144985"
/db_xref="GeneID:852823"
CDS complement(394966..395829)
/gene="GEP7"
/locus_tag="YGL057C"
/note="hypothetical protein; null mutant exhibits a
respiratory growth defect and synthetic interactions with
prohibitin (phb1) and gem1; authentic, non-tagged protein
is detected in highly purified mitochondria in
high-throughput studies"
/codon_start=1
/product="Gep7p"
/protein_id="NP_011458.1"
/db_xref="GI:6321381"
/db_xref="SGD:S000003025"
/db_xref="GeneID:852823"
/translation="MVLSNVKIFRLKSHRAFRIGPMIKAVAGNLLVKRFYQPKLERIP
PASLLLKQKIRLAQNGSTTSTENPISFSQTMSEIFSVLQPSAPDLDEDETSGLKRDHL
LTERLNNGELGVIMNKFFNPSSTHNNQLIDTNILLQNFPKLSGNDLDLLDFAINEKMR
GNWNDLKQDFIQLWYYKSFGFLGPRTQFVLTNSSPSVRSQFLKLPFIEYNWFLLQNNK
NANILPADVQNVVKVFHLDDKRFTWKSIDPFSKAIISFVVFVSIYVWLDESAKQKTKE
LPAQKSTVISE"
gene complement(396035..397618)
/gene="SDS23"
/locus_tag="YGL056C"
/db_xref="GeneID:852824"
mRNA complement(396035..397618)
/gene="SDS23"
/locus_tag="YGL056C"
/product="Sds23p"
/transcript_id="NM_001180921.2"
/db_xref="GI:330443556"
/db_xref="GeneID:852824"
CDS complement(396035..397618)
/gene="SDS23"
/locus_tag="YGL056C"
/note="One of two S. cerevisiae homologs (Sds23p and
Sds24p) of the S. pombe Sds23 protein, which is implicated
in APC/cyclosome regulation; involved in cell separation
during budding"
/codon_start=1
/product="Sds23p"
/protein_id="NP_011459.2"
/db_xref="GI:330443557"
/db_xref="SGD:S000003024"
/db_xref="GeneID:852824"
/translation="MPQNTRHTSIVEMLSTPPQLPNSTDLNSLSEQTDKNTEANKSDT
ESLHKSISKSSSSSSLSTLDNTEYSNNNGNSLSTLNSQNLLSVHRQEWQHTPLSNLVE
QNKLIFIRGSISVEEAFNTLVKHQLTSLPVENFPGDMNCLTFDYNDLNAYLLLVLNRI
KVSNDKITSDCQNGKSVPVGEIVKLTPKNPFYKLPETENLSTVIGILGSGVHRVAITN
VEMTQIKGILSQRRLIKYLWENARSFPNLKPLLDSSLEELNIGVLNAARDKPTFKQSR
VISIQGDEHLIMALHKMYVERISSIAVVDPQGNLIGNISVTDVKHVTRTSQYPLLHNT
CRHFVSVILNLRGLETGKDSFPIFHVYPTSSLARTFAKLVATKSHRLWIVQPNDNQPT
ASSEKSSSPSPSTPPVTTLPSLASSYHSNTQSSRMANSPVLKSSDTSNNKINVNINLS
GPSPSQPQSPSATMPPPQSPSNCPASPTPAHFEKEYRTGKLIGVVSLTDILSVLARKQ
THHKEIDPQMARKQRGHIG"
gene 398628..400160
/gene="OLE1"
/locus_tag="YGL055W"
/gene_synonym="MDM2"
/db_xref="GeneID:852825"
mRNA 398628..400160
/gene="OLE1"
/locus_tag="YGL055W"
/gene_synonym="MDM2"
/product="stearoyl-CoA 9-desaturase"
/transcript_id="NM_001180920.3"
/db_xref="GI:398364716"
/db_xref="GeneID:852825"
CDS 398628..400160
/gene="OLE1"
/locus_tag="YGL055W"
/gene_synonym="MDM2"
/EC_number="1.14.19.1"
/note="Delta(9) fatty acid desaturase, required for
monounsaturated fatty acid synthesis and for normal
distribution of mitochondria"
/codon_start=1
/product="stearoyl-CoA 9-desaturase"
/protein_id="NP_011460.3"
/db_xref="GI:398364717"
/db_xref="SGD:S000003023"
/db_xref="GeneID:852825"
/translation="MPTSGTTIELIDDQFPKDDSASSGIVDEVDLTEANILATGLNKK
APRIVNGFGSLMGSKEMVSVEFDKKGNEKKSNLDRLLEKDNQEKEEAKTKIHISEQPW
TLNNWHQHLNWLNMVLVCGMPMIGWYFALSGKVPLHLNVFLFSVFYYAVGGVSITAGY
HRLWSHRSYSAHWPLRLFYAIFGCASVEGSAKWWGHSHRIHHRYTDTLRDPYDARRGL
WYSHMGWMLLKPNPKYKARADITDMTDDWTIRFQHRHYILLMLLTAFVIPTLICGYFF
NDYMGGLIYAGFIRVFVIQQATFCINSLAHYIGTQPFDDRRTPRDNWITAIVTFGEGY
HNFHHEFPTDYRNAIKWYQYDPTKVIIYLTSLVGLAYDLKKFSQNAIEEALIQQEQKK
INKKKAKINWGPVLTDLPMWDKQTFLAKSKENKGLVIISGIVHDVSGYISEHPGGETL
IKTALGKDATKAFSGGVYRHSNAAQNVLADMRVAVIKESKNSAIRMASKRGEIYETGK
FF"
gene complement(400871..401287)
/gene="ERV14"
/locus_tag="YGL054C"
/db_xref="GeneID:852826"
mRNA complement(400871..401287)
/gene="ERV14"
/locus_tag="YGL054C"
/product="Erv14p"
/transcript_id="NM_001180919.1"
/db_xref="GI:296144988"
/db_xref="GeneID:852826"
CDS complement(400871..401287)
/gene="ERV14"
/locus_tag="YGL054C"
/note="Protein localized to COPII-coated vesicles,
involved in vesicle formation and incorporation of
specific secretory cargo; required for the delivery of
bud-site selection protein Axl2p to cell surface; related
to Drosophila cornichon"
/codon_start=1
/product="Erv14p"
/protein_id="NP_011461.1"
/db_xref="GI:6321384"
/db_xref="SGD:S000003022"
/db_xref="GeneID:852826"
/translation="MGAWLFILAVVVNCINLFGQVHFTILYADLEADYINPIELCSKV
NKLITPEAALHGALSLLFLLNGYWFVFLLNLPVLAYNLNKIYNKVQLLDATEIFRTLG
KHKRESFLKLGFHLLMFFFYLYRMIMALIAESGDDF"
gene complement(401527..401598)
/locus_tag="tE(UUC)G2"
/db_xref="GeneID:852827"
tRNA complement(401527..401598)
/locus_tag="tE(UUC)G2"
/product="tRNA-Glu"
/note="Glutamate tRNA (tRNA-Glu), predicted by tRNAscan-SE
analysis; thiolation of uridine at wobble position (34)
requires Ncs6p"
/db_xref="SGD:S000006554"
/db_xref="GeneID:852827"
LTR 401616..401894
/note="Ty3 LTR"
/db_xref="SGD:S000006949"
LTR 401959..402290
/note="Ty1 LTR"
/db_xref="SGD:S000006944"
gene 402589..403302
/gene="PRM8"
/locus_tag="YGL053W"
/db_xref="GeneID:852828"
mRNA 402589..403302
/gene="PRM8"
/locus_tag="YGL053W"
/product="Prm8p"
/transcript_id="NM_001180918.1"
/db_xref="GI:296144989"
/db_xref="GeneID:852828"
CDS 402589..403302
/gene="PRM8"
/locus_tag="YGL053W"
/note="Pheromone-regulated protein with 2 predicted
transmembrane segments and an FF sequence, a motif
involved in COPII binding; forms a complex with Prp9p in
the ER; member of DUP240 gene family"
/codon_start=1
/product="Prm8p"
/protein_id="NP_011462.1"
/db_xref="GI:6321385"
/db_xref="SGD:S000003021"
/db_xref="GeneID:852828"
/translation="MQTPSENTNAKSDSLDEPGAYLIEENVALPKDIFHSYLSYWIYE
AAHCTPVMLLSLVIGVLISIIILFHDNENCVGVSVGFLLIFSGILVIVLILRFGPQIS
DEDFKCKLLMEIITRKPTVKGKEWRTITYKMNQYLFDNDLWNTPYYFYRDEDCHRYFL
SLIKGRTFKKQKESSASNVKDAQSNDETAGTPNEAAESSSFSAGPNFIKLLTKAAEIE
QQFQKEYWRQEYPGVDEFF"
gene 403687..404391
/gene="MST27"
/locus_tag="YGL051W"
/db_xref="GeneID:852830"
mRNA 403687..404391
/gene="MST27"
/locus_tag="YGL051W"
/product="Mst27p"
/transcript_id="NM_001180916.1"
/db_xref="GI:296144990"
/db_xref="GeneID:852830"
CDS 403687..404391
/gene="MST27"
/locus_tag="YGL051W"
/note="Putative integral membrane protein, involved in
vesicle formation; forms complex with Mst28p; member of
DUP240 gene family; binds COPI and COPII vesicles"
/codon_start=1
/product="Mst27p"
/protein_id="NP_011464.1"
/db_xref="GI:6321387"
/db_xref="SGD:S000003019"
/db_xref="GeneID:852830"
/translation="MQTPLESTDVKLDTLNEPSAHLIEKNVALPKDIFRSYLSYWIYE
IARYTPVMILSLVIGVLVLLIIFFNDNEACVFNSAYYAYLSLVVLLIILGDGNPKLVS
RRNFRTELLVDVITRKPAVEGKEWRIITYNMNQYLFNHGQWHTPYYFYSDEDCYRYFL
RLVEGVTPKKQTATSIGNSPVTAKPEDAIESASPSSRLNYRNFLLKAAEIERQAQENY
WRRRHPNIDALLKKTE"
LTR 405004..405145
/note="Ty1 LTR"
/db_xref="SGD:S000006945"
LTR 405146..405207
/note="Ty1 LTR"
/db_xref="SGD:S000006946"
LTR complement(405208..405453)
/note="Ty3 LTR"
/db_xref="SGD:S000006938"
gene 405470..405541
/locus_tag="tR(UCU)G1"
/db_xref="GeneID:852831"
tRNA 405470..405541
/locus_tag="tR(UCU)G1"
/product="tRNA-Arg"
/note="Arginine tRNA (tRNA-Arg), predicted by tRNAscan-SE
analysis; one of 11 nuclear tRNA genes containing the
tDNA-anticodon UCU (converted to mcm5-UCU in the mature
tRNA), decodes AGA codons into arginine, one of 19 nuclear
tRNAs for arginine"
/db_xref="SGD:S000006711"
/db_xref="GeneID:852831"
gene 405776..406597
/gene="TYW3"
/locus_tag="YGL050W"
/db_xref="GeneID:852832"
mRNA 405776..406597
/gene="TYW3"
/locus_tag="YGL050W"
/product="Tyw3p"
/transcript_id="NM_001180915.3"
/db_xref="GI:398364738"
/db_xref="GeneID:852832"
CDS 405776..406597
/gene="TYW3"
/locus_tag="YGL050W"
/EC_number="2.1.1.-"
/note="tRNA methyltransferase required for synthesis of
wybutosine, a modified guanosine found at the 3'-position
adjacent to the anticodon of phenylalanine tRNA which
supports reading frame maintenance by stabilizing
codon-anticodon interactions"
/codon_start=1
/product="Tyw3p"
/protein_id="NP_011465.3"
/db_xref="GI:398364739"
/db_xref="SGD:S000003018"
/db_xref="GeneID:852832"
/translation="MAAQNAFEQKKRAILNEIDSTQPDLSPKGTIDELCLPIIDLINA
SADMVTTSSCSGRVSVFLEGTKSYNGEVKIGGKGQGGKWLYVTHDREKVIGWLDELKS
KSEFSFELSGKEIPTEKVTGSIRYILYKYEPFILHVKCRDFQAASKLYNTAMSCGFRE
SGIGSNNLVAIRINIKLDVPLGYLDETSGTLKFFVTPEYVSVLDSLSLSKFDENTRKM
QALYDRIEKELINCAPDVNSKVNITPIETKEERRERKKREGMERQRQLKSPQNVL"
gene complement(406860..409604)
/gene="TIF4632"
/locus_tag="YGL049C"
/db_xref="GeneID:852833"
mRNA complement(406860..409604)
/gene="TIF4632"
/locus_tag="YGL049C"
/product="Tif4632p"
/transcript_id="NM_001180914.1"
/db_xref="GI:296144992"
/db_xref="GeneID:852833"
CDS complement(406860..409604)
/gene="TIF4632"
/locus_tag="YGL049C"
/note="Translation initiation factor eIF4G, subunit of the
mRNA cap-binding protein complex (eIF4F) that also
contains eIF4E (Cdc33p); associates with the
poly(A)-binding protein Pab1p, also interacts with eIF4A
(Tif1p); TIF4632 has a paralog, TIF4631, that arose from
the whole genome duplication"
/codon_start=1
/product="Tif4632p"
/protein_id="NP_011466.1"
/db_xref="GI:6321389"
/db_xref="SGD:S000003017"
/db_xref="GeneID:852833"
/translation="MTDQRGPPPPHPQQANGYKKFPPHDNQYSGANNSQPNNHYNENL
YSAREPHNNKQYQSKNGKYGTNKYNNRNNSQGNAQYYNNRFNNGYRLNNNDYNPAMLP
GMQWPANYYAPQMYYIPQQMVPVASPPYTHQPLNTNPEPPSTPKTTKIEITTKTGERL
NLKKFHEEKKASKGEEKNDGVEQKSKSGTPFEKEATPVLPANEAVKDTLTETSNEKST
SEAENTKRLFLEQVRLRKAAMERKKNGLISETEKKQETSNHDNTDTTKPNSVIESEPI
KEAPKPTGEANEVVIDGKSGASVKTPQHVTGSVTKSVTFNEPENESSSQDVDELVKDD
DTTEISDTTGGKTVNKSDDETINSVITTEENTVKETEPSTSDIEMPTVSQLLETLGKA
QPISDIYEFAYPENVERPDIKYKKPSVKYTYGPTFLLQFKDKLKFRPDPAWVEAVSSK
IVIPPHIARNKPKDSGRFGGDFRSPSMRGMDHTSSSRVSSKRRSKRMGDDRRSNRGYT
SRKDREKAAEKAEEQAPKEEIAPLVPSANRWIPKSRVKKTEKKLAPDGKTELFDKEEV
ERKMKSLLNKLTLEMFDSISSEILDIANQSKWEDDGETLKIVIEQIFHKACDEPHWSS
MYAQLCGKVVKDLDPNIKDKENEGKNGPKLVLHYLVARCHEEFEKGWADKLPAGEDGN
PLEPEMMSDEYYIAAAAKRRGLGLVRFIGYLYCLNLLTGKMMFECFRRLMKDLNNDPS
EETLESVIELLNTVGEQFEHDKFVTPQATLEGSVLLDNLFMLLQHIIDGGTISNRIKF
KLIDVKELREIKHWNSAKKDAGPKTIQQIHQEEEQLRQKKNSQRSNSRFNNHNQSNSN
RYSSNRRNMQNTQRDSFASTKTGSFRNNQRNARKVEEVSQAPRANMFDALMNNDGDSD
"
gene complement(410069..411286)
/gene="RPT6"
/locus_tag="YGL048C"
/gene_synonym="CIM3; CRL3; SCB68; SUG1"
/db_xref="GeneID:852834"
mRNA complement(410069..411286)
/gene="RPT6"
/locus_tag="YGL048C"
/gene_synonym="CIM3; CRL3; SCB68; SUG1"
/product="proteasome regulatory particle base subunit
RPT6"
/transcript_id="NM_001180913.1"
/db_xref="GI:296144993"
/db_xref="GeneID:852834"
CDS complement(410069..411286)
/gene="RPT6"
/locus_tag="YGL048C"
/gene_synonym="CIM3; CRL3; SCB68; SUG1"
/note="ATPase of the 19S regulatory particle of the 26S
proteasome; one of six ATPases of the regulatory particle;
involved in the degradation of ubiquitinated substrates;
bound by ubiquitin-protein ligases Ubr1p and Ufd4p;
localized mainly to the nucleus throughout the cell cycle;
protein abundance increases in response to DNA replication
stress"
/codon_start=1
/product="proteasome regulatory particle base subunit
RPT6"
/protein_id="NP_011467.1"
/db_xref="GI:6321390"
/db_xref="SGD:S000003016"
/db_xref="GeneID:852834"
/translation="MTAAVTSSNIVLETHESGIKPYFEQKIQETELKIRSKTENVRRL
EAQRNALNDKVRFIKDELRLLQEPGSYVGEVIKIVSDKKVLVKVQPEGKYIVDVAKDI
NVKDLKASQRVCLRSDSYMLHKVLENKADPLVSLMMVEKVPDSTYDMVGGLTKQIKEI
KEVIELPVKHPELFESLGIAQPKGVILYGPPGTGKTLLARAVAHHTDCKFIRVSGAEL
VQKYIGEGSRMVRELFVMAREHAPSIIFMDEIDSIGSTRVEGSGGGDSEVQRTMLELL
NQLDGFETSKNIKIIMATNRLDILDPALLRPGRIDRKIEFPPPSVAARAEILRIHSRK
MNLTRGINLRKVAEKMNGCSGADVKGVCTEAGMYALRERRIHVTQEDFELAVGKVMNK
NQETAISVAKLFK"
gene 411552..412160
/gene="ALG13"
/locus_tag="YGL047W"
/db_xref="GeneID:852835"
mRNA 411552..412160
/gene="ALG13"
/locus_tag="YGL047W"
/product="N-acetylglucosaminyldiphosphodolichol
N-acetylglucosaminyltransferase catalytic subunit ALG13"
/transcript_id="NM_001180912.1"
/db_xref="GI:296144994"
/db_xref="GeneID:852835"
CDS 411552..412160
/gene="ALG13"
/locus_tag="YGL047W"
/EC_number="2.4.1.141"
/note="Catalytic component of UDP-GlcNAc transferase;
required for the second step of dolichyl-linked
oligosaccharide synthesis; anchored to the ER membrane via
interaction with Alg14p; similar to bacterial and human
glycosyltransferases; protein abundance increases in
response to DNA replication stress"
/codon_start=1
/product="N-acetylglucosaminyldiphosphodolichol
N-acetylglucosaminyltransferase catalytic subunit ALG13"
/protein_id="NP_011468.1"
/db_xref="GI:6321391"
/db_xref="SGD:S000003015"
/db_xref="GeneID:852835"
/translation="MGIIEEKALFVTCGATVPFPKLVSCVLSDEFCQELIQYGFVRLI
IQFGRNYSSEFEHLVQERGGQRESQKIPIDQFGCGDTARQYVLMNGKLKVIGFDFSTK
MQSIIRDYSDLVISHAGTGSILDSLRLNKPLIVCVNDSLMDNHQQQIADKFVELGYVW
SCAPTETGLIAGLRASQTEKLKPFPVSHNPSFERLLVETIYS"
gene complement(412294..412367)
/locus_tag="tV(AAC)G1"
/db_xref="GeneID:852836"
tRNA complement(412294..412367)
/locus_tag="tV(AAC)G1"
/product="tRNA-Val"
/note="Valine tRNA (tRNA-Val), predicted by tRNAscan-SE
analysis"
/db_xref="SGD:S000006755"
/db_xref="GeneID:852836"
LTR 412456..412725
/note="Ty1 LTR"
/db_xref="SGD:S000006947"
gene 414102..415730
/gene="RIM8"
/locus_tag="YGL045W"
/gene_synonym="ART9; PAL3; YGL046W"
/db_xref="GeneID:852837"
mRNA 414102..415730
/gene="RIM8"
/locus_tag="YGL045W"
/gene_synonym="ART9; PAL3; YGL046W"
/product="Rim8p"
/transcript_id="NM_001180910.3"
/db_xref="GI:398364762"
/db_xref="GeneID:852837"
CDS 414102..415730
/gene="RIM8"
/locus_tag="YGL045W"
/gene_synonym="ART9; PAL3; YGL046W"
/note="Protein involved in proteolytic activation of
Rim101p in response to alkaline pH; interacts with ESCRT-1
subunits Stp22p and Vps28p; essential for anaerobic
growth; member of the arrestin-related trafficking adaptor
family"
/codon_start=1
/product="Rim8p"
/protein_id="NP_011470.4"
/db_xref="GI:398364763"
/db_xref="SGD:S000003013"
/db_xref="GeneID:852837"
/translation="MSLLRLWNKESRAPSKIKSHGIVGSYGNSMLAHNNVKQFRIDID
EPHRVWKPNESITGEAVIDIKRDITNVAIKLSLVCEVRVKTGNSPTSKNKRIEKTLEK
STFLYGQDYVKTAFSAKEKKPHVDKTTILNGLSKGEHRFPFRIRIPRGRGMLSSIKFE
RGSITYFLSCTLESLNNINGLKKPEARCEREFAVIVPLDVSRLPKPKTKTVVLQSASM
VQNKKNKSTEDESSSYTQLTQKSTTSNSSSSSVNSKTSPLPNKTVTISVDIPQAGFMI
GEIIPIDVKIDHYKPFYAPAGLTTTLVRICRVGGAGKDDPMETFRKDICQSISPIYIN
PETLQFQSRVYLKVPLDAFSTLTTVGKFFSFQYYIEVMVNLSKKNVVYTESNRIIGTP
IGEQNGLGVENNINRIQRKMLRMVNPETLENDSEGYESSIFFKDMVNVEKLKRLRNVT
GMSIETVIGTTRSEQQQSDASIPSQSSITAPQNSPSNLRDWLAPLNAYDSDDVPVPKY
SPNDKVSVPSEDKQELEQKRLQQLESDPPPCDDY"
gene complement(416146..417036)
/gene="RNA15"
/locus_tag="YGL044C"
/db_xref="GeneID:852838"
mRNA complement(416146..417036)
/gene="RNA15"
/locus_tag="YGL044C"
/product="Rna15p"
/transcript_id="NM_001180909.1"
/db_xref="GI:296144996"
/db_xref="GeneID:852838"
CDS complement(416146..417036)
/gene="RNA15"
/locus_tag="YGL044C"
/note="Component of the cleavage and polyadenylation
factor I (CF I); CF 1, composed of the CF 1A complex
(Rna14p, Rna15p, Clp1p, Pcf11p) and Hrp1, is involved in
cleavage and polyadenylation of mRNA 3' ends; interacts
with the A-rich polyadenylation signal in complex with
Rna14p and Hrp1p; mutant displays reduced transcription
elongation in the G-less-based run-on (GLRO) assay;
required for gene looping"
/codon_start=1
/product="Rna15p"
/protein_id="NP_011471.1"
/db_xref="GI:6321394"
/db_xref="SGD:S000003012"
/db_xref="GeneID:852838"
/translation="MNRQSGVNAGVQNNPPSRVVYLGSIPYDQTEEQILDLCSNVGPV
INLKMMFDPQTGRSKGYAFIEFRDLESSASAVRNLNGYQLGSRFLKCGYSSNSDISGV
SQQQQQQYNNINGNNNNNGNNNNNSNGPDFQNSGNANFLSQKFPELPSGIDVNINMTT
PAMMISSELAKKPKEVQLKFLQKFQEWTRAHPEDAVSLLELCPQLSFVTAELLLTNGI
CKVDDLIPLASRPQEEASATNNNSVNEVVDPAVLNKQKELLKQVLQLNDSQISILPDD
ERMAIWDLKQKALRGEFGAF"
gene 417483..418412
/gene="DST1"
/locus_tag="YGL043W"
/gene_synonym="PPR2"
/db_xref="GeneID:852839"
mRNA 417483..418412
/gene="DST1"
/locus_tag="YGL043W"
/gene_synonym="PPR2"
/product="Dst1p"
/transcript_id="NM_001180908.1"
/db_xref="GI:296144997"
/db_xref="GeneID:852839"
CDS 417483..418412
/gene="DST1"
/locus_tag="YGL043W"
/gene_synonym="PPR2"
/note="General transcription elongation factor TFIIS,
enables RNA polymerase II to read through blocks to
elongation by stimulating cleavage of nascent transcripts
stalled at transcription arrest sites; maintains RNAPII
elongation activity on ribosomal protein genes during
conditions of transcriptional stress"
/codon_start=1
/product="Dst1p"
/protein_id="NP_011472.1"
/db_xref="GI:6321395"
/db_xref="SGD:S000003011"
/db_xref="GeneID:852839"
/translation="MDSKEVLVHVKNLEKNKSNDAAVLEILHVLDKEFVPTEKLLRET
KVGVEVNKFKKSTNVEISKLVKKMISSWKDAINKNKRSRQAQQHHQDHAPGNAEDKTT
VGESVNGVQQPASSQSDAMKQDKYVSTKPRNSKNDGVDTAIYHHKLRDQVLKALYDVL
AKESEHPPQSILHTAKAIESEMNKVNNCDTNEAAYKARYRIIYSNVISKNNPDLKHKI
ANGDITPEFLATCDAKDLAPAPLKQKIEEIAKQNLYNAQGATIERSVTDRFTCGKCKE
KKVSYYQLQTRSADEPLTTFCTCEACGNRWKFS"
gene complement(418704..418886)
/locus_tag="YGL041C-B"
/db_xref="GeneID:1466454"
mRNA complement(418704..418886)
/locus_tag="YGL041C-B"
/product="hypothetical protein"
/transcript_id="NM_001184550.1"
/db_xref="GI:296144998"
/db_xref="GeneID:1466454"
CDS complement(418704..418886)
/locus_tag="YGL041C-B"
/note="hypothetical protein; identified by fungal homology
and RT-PCR"
/codon_start=1
/product="hypothetical protein"
/protein_id="NP_878074.1"
/db_xref="GI:33438792"
/db_xref="SGD:S000028548"
/db_xref="GeneID:1466454"
/translation="MFDSSIERVTLELCFHITLSIMCGCSIYFLLLVFILTFYSSVLL
HLKLYFFSSDRAIFNA"
gene 418825..419289
/locus_tag="YGL041W-A"
/db_xref="GeneID:5814844"
mRNA 418825..419289
/locus_tag="YGL041W-A"
/product="hypothetical protein"
/transcript_id="NM_001184647.4"
/db_xref="GI:398364778"
/db_xref="GeneID:5814844"
CDS 418825..419289
/locus_tag="YGL041W-A"
/note="hypothetical protein, conserved in fungi;
identified by expression profiling and mass spectrometry"
/codon_start=1
/product="hypothetical protein"
/protein_id="NP_001106172.4"
/db_xref="GI:398364779"
/db_xref="SGD:S000028826"
/db_xref="GeneID:5814844"
/translation="MLRVIWKHSSRVTRSIELSNISTTNHTRSLRRLSWISPRRFYAQ
SWDDRQPNDKIDAHIKVQKLMDQINSRPNVLEKLEKVSNIMIEKKLVNLDGTSANEEN
TMKPWQMIKILMDRDLRHAMKEFKLELEKSGIQLGPEQLAPLMTVLGLEKKK"
gene complement(419527..420555)
/gene="HEM2"
/locus_tag="YGL040C"
/gene_synonym="OLE4; SLU1"
/db_xref="GeneID:852842"
mRNA complement(419527..420555)
/gene="HEM2"
/locus_tag="YGL040C"
/gene_synonym="OLE4; SLU1"
/product="porphobilinogen synthase HEM2"
/transcript_id="NM_001180905.1"
/db_xref="GI:296145000"
/db_xref="GeneID:852842"
CDS complement(419527..420555)
/gene="HEM2"
/locus_tag="YGL040C"
/gene_synonym="OLE4; SLU1"
/EC_number="4.2.1.24"
/note="Aminolevulinate dehydratase, a homo-octameric
enzyme, catalyzes the conversion of 5-aminolevulinate to
porphobilinogen, the second step in heme biosynthesis;
enzymatic activity is zinc-dependent; localizes to the
cytoplasm and nucleus"
/codon_start=1
/product="porphobilinogen synthase HEM2"
/protein_id="NP_011475.1"
/db_xref="GI:6321398"
/db_xref="SGD:S000003008"
/db_xref="GeneID:852842"
/translation="MHTAEFLETEPTEISSVLAGGYNHPLLRQWQSERQLTKNMLIFP
LFISDNPDDFTEIDSLPNINRIGVNRLKDYLKPLVAKGLRSVILFGVPLIPGTKDPVG
TAADDPAGPVIQGIKFIREYFPELYIICDVCLCEYTSHGHCGVLYDDGTINRERSVSR
LAAVAVNYAKAGAHCVAPSDMIDGRIRDIKRGLINANLAHKTFVLSYAAKFSGNLYGP
FRDAACSAPSNGDRKCYQLPPAGRGLARRALERDMSEGADGIIVKPSTFYLDIMRDAS
EICKDLPICAYHVSGEYAMLHAAAEKGVVDLKTIAFESHQGFLRAGARLIITYLAPEF
LDWLDEEN"
rep_origin 421090..421338
/note="ARS718;
Autonomously Replicating Sequence"
/db_xref="SGD:S000118458"
gene 423092..423205
/gene="SUP54"
/locus_tag="tL(CAA)G2"
/db_xref="GeneID:852843"
tRNA join(423092..423129,423162..423205)
/gene="SUP54"
/locus_tag="tL(CAA)G2"
/product="tRNA-Leu"
/note="Leucine tRNA (tRNA-Leu), predicted by tRNAscan-SE
analysis; can mutate to suppress amber nonsense mutations"
/db_xref="SGD:S000006640"
/db_xref="GeneID:852843"
gene 423961..425007
/locus_tag="YGL039W"
/db_xref="GeneID:852844"
mRNA 423961..425007
/locus_tag="YGL039W"
/product="carbonyl reductase (NADPH-dependent)"
/transcript_id="NM_001180904.1"
/db_xref="GI:296145001"
/db_xref="GeneID:852844"
CDS 423961..425007
/locus_tag="YGL039W"
/EC_number="1.1.1.-"
/note="Oxidoreductase shown to reduce carbonyl compounds
to chiral alcohols"
/codon_start=1
/product="carbonyl reductase (NADPH-dependent)"
/protein_id="NP_011476.1"
/db_xref="GI:6321399"
/db_xref="SGD:S000003007"
/db_xref="GeneID:852844"
/translation="MTTEKTVVFVSGATGFIALHVVDDLLKTGYKVIGSGRSQEKNDG
LLKKFKSNPNLSMEIVEDIAAPNAFDKVFQKHGKEIKVVLHIASPVHFNTTDFEKDLL
IPAVNGTKSILEAIKNYAADTVEKVVITSSVAALASPGDMKDTSFVVNEESWNKDTWE
SCQANAVSAYCGSKKFAEKTAWDFLEENQSSIKFTLSTINPGFVFGPQLFADSLRNGI
NSSSAIIANLVSYKLGDNFYNYSGPFIDVRDVSKAHLLAFEKPECAGQRLFLCEDMFC
SQEALDILNEEFPQLKGKIATGEPGSGSTFLTKNCCKCDNRKTKNLLGFQFNKFRDCI
VDTASQLLEVQSKS"
gene complement(425362..426804)
/gene="OCH1"
/locus_tag="YGL038C"
/gene_synonym="LDB12; NGD29"
/db_xref="GeneID:852845"
mRNA complement(425362..426804)
/gene="OCH1"
/locus_tag="YGL038C"
/gene_synonym="LDB12; NGD29"
/product="Och1p"
/transcript_id="NM_001180903.1"
/db_xref="GI:296145002"
/db_xref="GeneID:852845"
CDS complement(425362..426804)
/gene="OCH1"
/locus_tag="YGL038C"
/gene_synonym="LDB12; NGD29"
/EC_number="2.4.1.232"
/note="Mannosyltransferase of the cis-Golgi apparatus,
initiates the polymannose outer chain elongation of
N-linked oligosaccharides of glycoproteins"
/codon_start=1
/product="Och1p"
/protein_id="NP_011477.1"
/db_xref="GI:6321400"
/db_xref="SGD:S000003006"
/db_xref="GeneID:852845"
/translation="MSRKLSHLIATRKSKTIVVTVLLIYSLLTFHLSNKRLLSQFYPS
KDDFKQTLLPTTSHSQDINLKKQITVNKKKNQLHNLRDQLSFAFPYDSQAPIPQRVWQ
TWKVGADDKNFPSSFRTYQKTWSGSYSPDYQYSLISDDSIIPFLENLYAPVPIVIQAF
KLMPGNILKADFLRYLLLFARGGIYSDMDTMLLKPIDSWPSQNKSWLNNIIDLNKPIP
YKNSKPSLLSSDEISHQPGLVIGIEADPDRDDWSEWYARRIQFCQWTIQAKPGHPILR
ELILNITATTLASVQNPGVPVSEMIDPRFEEDYNVNYRHKRRHDETYKHSELKNNKNV
DGSDIMNWTGPGIFSDIIFEYMNNVLRYNSDILLINPNLNKNDEEGSESATTPAKDVD
NDTLSKSTRKFYKKISESLQSSNSMPWEFFSFLKEPVIVDDVMVLPITSFSPDVGQMG
AQSSDDKMAFVKHMFSGSWKEDADKNAGHK"
gene complement(427297..427947)
/gene="PNC1"
/locus_tag="YGL037C"
/db_xref="GeneID:852846"
mRNA complement(427297..427947)
/gene="PNC1"
/locus_tag="YGL037C"
/product="nicotinamidase"
/transcript_id="NM_001180902.3"
/db_xref="GI:398364806"
/db_xref="GeneID:852846"
CDS complement(427297..427947)
/gene="PNC1"
/locus_tag="YGL037C"
/EC_number="3.5.1.19"
/note="Nicotinamidase that converts nicotinamide to
nicotinic acid; part of the NAD(+) salvage pathway;
required for life span extension by calorie restriction;
PNC1 expression responds to all known stimuli that extend
replicative life span; protein increases in abundance and
relative distribution to cytoplasmic foci decreases upon
DNA replication stress"
/codon_start=1
/product="nicotinamidase"
/protein_id="NP_011478.3"
/db_xref="GI:398364807"
/db_xref="SGD:S000003005"
/db_xref="GeneID:852846"
/translation="MKTLIVVDMQNDFISPLGSLTVPKGEELINPISDLMQDADRDWH
RIVVTRDWHPSRHISFAKNHKDKEPYSTYTYHSPRPGDDSTQEGILWPVHCVKNTWGS
QLVDQIMDQVVTKHIKIVDKGFLTDREYYSAFHDIWNFHKTDMNKYLEKHHTDEVYIV
GVALEYCVKATAISAAELGYKTTVLLDYTRPISDDPEVINKVKEELKAHNINVVDK"
gene 428601..431330
/locus_tag="YGL036W"
/db_xref="GeneID:852847"
mRNA 428601..431330
/locus_tag="YGL036W"
/product="hypothetical protein"
/transcript_id="NM_001180901.1"
/db_xref="GI:296145004"
/db_xref="GeneID:852847"
CDS 428601..431330
/locus_tag="YGL036W"
/note="hypothetical protein; green fluorescent protein
(GFP)-fusion protein localizes to the cytoplasm; YGL036W
is not an essential gene"
/codon_start=1
/product="hypothetical protein"
/protein_id="NP_011479.1"
/db_xref="GI:6321402"
/db_xref="SGD:S000003004"
/db_xref="GeneID:852847"
/translation="MQKCAGHAPLVTAASRVSQDTVDALLQAILKAYHKLASIDSHIN
DPVEIAFKLINSFKYLPISGSSVKDFESELRELDVFSPLLQSAVTAANNSNIIWDLIA
VLFAYISIHKQLHPLILHNLNIWKDFMADNDEETATTTDGDSMNFGVLSLLSIVQNFE
EITPNLFEFLKLGLRSTLLKIWVAQWQRYDPSATNLINGDEKISSWITKDYQVDFFII
TSLASTSSLEVLPSHYFVYKISKRISHFPNLIDPKLYRSAISTIMENGISDNGGGENS
SDKIDPTDLSFHLQVLMEVIDHPELNYLQENRLILLLDIALNYLILVPTHCLHSNFGE
LGSTQSLASTLNIIQFLLSKFLINMGSISQLINQYNRKCITTNNINNNNINNNGVING
STNTTSTTTTTITNNNNNSNNSSISNNNRKIDWTQSYQTRYQIPYWFEDSILPPIPPI
SKSLFTFDKNLDHESDSIMIVNDVLRCLNLTILLISKLLRDYDDLKINPLIQSSDDHS
NEDNHVIIEQYMQLYLVPLFTSLLLAQQLKDRGQERDEGHKEKEENINLIGSSSVKKL
FSQLIFFSSLKLCENLVIKEKNLALYHLIKFATKVSLDDLILQKISINLLNHLFFHQI
RDGSDDDNLIKKLCLKNQLSFQALKDYITLWNDGSEVYNAFYKELFYEEQPKIKPIKL
TTSDLLKLFPEDVQFVISTPPNTITSASTSDNCTSSQSAAQKNIENFTTLSKYDVYSS
TSFIPSTSKNTNTNVSKQQQQPQNSTPCSSNRFLFNKSSLISQESNGSNNNSGTQGPG
SMNESYSLDNSFNTTNTNMTRQPTTLTRATDAMTTAPTTPIPYKNTSGSSNNNLWIES
PMTNFKGSTISKSTNKSKMVNTGKNYILGGHNKVKNNSRAQSIHIDDFENENN"
gene complement(431548..433062)
/gene="MIG1"
/locus_tag="YGL035C"
/gene_synonym="CAT4; SSN1; TDS22"
/db_xref="GeneID:852848"
mRNA complement(431548..433062)
/gene="MIG1"
/locus_tag="YGL035C"
/gene_synonym="CAT4; SSN1; TDS22"
/product="Mig1p"
/transcript_id="NM_001180900.1"
/db_xref="GI:296145005"
/db_xref="GeneID:852848"
CDS complement(431548..433062)
/gene="MIG1"
/locus_tag="YGL035C"
/gene_synonym="CAT4; SSN1; TDS22"
/note="Transcription factor involved in glucose
repression; sequence specific DNA binding protein
containing two Cys2His2 zinc finger motifs; regulated by
the SNF1 kinase and the GLC7 phosphatase; regulates
filamentous growth along with Mig2p in response to glucose
depletion"
/codon_start=1
/product="Mig1p"
/protein_id="NP_011480.1"
/db_xref="GI:6321403"
/db_xref="SGD:S000003003"
/db_xref="GeneID:852848"
/translation="MQSPYPMTQVSNVDDGSLLKESKSKSKVAAKSEAPRPHACPICH
RAFHRLEHQTRHMRIHTGEKPHACDFPGCVKRFSRSDELTRHRRIHTNSHPRGKRGRK
KKVVGSPINSASSSATSIPDLNTANFSPPLPQQHLSPLIPIAIAPKENSSRSSTRKGR
KTKFEIGESGGNDPYMVSSPKTMAKIPVSVKPPPSLALNNMNYQTSSASTALSSLSNS
HSGSRLKLNALSSLQMMTPIASSAPRTVFIDGPEQKQLQQQQNSLSPRYSNTVILPRP
RSLTDFQGLNNANPNNNGSLRAQTQSSVQLKRPSSVLSLNDLLVGQRNTNESDSDFTT
GGEDEEDGLKDPSNSSIDNLEQDYLQEQSRKKSKTSTPTTMLSRSTSGTNLHTLGYVM
NQNHLHFSSSSPDFQKELNNRLLNVQQQQQEQHTLLQSQNTSNQSQNQNQNQMMASSS
SLSTTPLLLSPRVNMINTAISTQQTPISQSDSQVQELETLPPIRSLPLPFPHMD"
gene 435625..436351
/gene="HOP2"
/locus_tag="YGL033W"
/db_xref="GeneID:852850"
mRNA join(435625..435679,435750..436351)
/gene="HOP2"
/locus_tag="YGL033W"
/product="Hop2p"
/transcript_id="NM_001180898.1"
/db_xref="GI:296145006"
/db_xref="GeneID:852850"
CDS join(435625..435679,435750..436351)
/gene="HOP2"
/locus_tag="YGL033W"
/note="Meiosis-specific protein that localizes to
chromosomes, preventing synapsis between nonhomologous
chromosomes and ensuring synapsis between homologs;
complexes with Mnd1p to promote homolog pairing and
meiotic double-strand break repair"
/codon_start=1
/product="Hop2p"
/protein_id="NP_011482.2"
/db_xref="GI:9755333"
/db_xref="SGD:S000003001"
/db_xref="GeneID:852850"
/translation="MAPKKKSNDRAIQAKGSEAEQLIEDYLVSQYKPFSVNDIVQNLH
NKVTKTTATKALENLVNEKRIVSKTFGKIIIYSCNEQDTALPSNIDPSQFDFETVLQL
RNDLIELERDKSTAKDALDSVTKEPENEDLLTIIENEENELKKIESKLQSLQDDWDPA
NDEIVKRIMSEDTLLQKEITKRSKICKNLIATIKDSVCPKNMNEFLVCILNIFRDLFF
"
gene complement(436570..436833)
/gene="AGA2"
/locus_tag="YGL032C"
/db_xref="GeneID:852851"
mRNA complement(436570..436833)
/gene="AGA2"
/locus_tag="YGL032C"
/product="Aga2p"
/transcript_id="NM_001180897.3"
/db_xref="GI:398364826"
/db_xref="GeneID:852851"
CDS complement(436570..436833)
/gene="AGA2"
/locus_tag="YGL032C"
/note="Adhesion subunit of a-agglutinin of a-cells,
C-terminal sequence acts as a ligand for alpha-agglutinin
(Sag1p) during agglutination, modified with O-linked
oligomannosyl chains, linked to anchorage subunit Aga1p
via two disulfide bonds"
/codon_start=1
/product="Aga2p"
/protein_id="NP_011483.3"
/db_xref="GI:398364827"
/db_xref="SGD:S000003000"
/db_xref="GeneID:852851"
/translation="MQLLRCFSIFSVIASVLAQELTTICEQIPSPTLESTPYSLSTTT
ILANGKAMQGVFEYYKSVTFVSNCGSHPSTTSKGSPINTQYVF"
gene complement(437467..437934)
/gene="RPL24A"
/locus_tag="YGL031C"
/gene_synonym="RPL30A"
/db_xref="GeneID:852852"
mRNA complement(437467..437934)
/gene="RPL24A"
/locus_tag="YGL031C"
/gene_synonym="RPL30A"
/product="ribosomal 60S subunit protein L24A"
/transcript_id="NM_001180896.1"
/db_xref="GI:296145008"
/db_xref="GeneID:852852"
CDS complement(437467..437934)
/gene="RPL24A"
/locus_tag="YGL031C"
/gene_synonym="RPL30A"
/note="Ribosomal 60S subunit protein L24A; not essential
for translation but may be required for normal translation
rate; homologous to mammalian ribosomal protein L24, no
bacterial homolog; RPL24A has a paralog, RPL24B, that
arose from the whole genome duplication"
/codon_start=1
/product="ribosomal 60S subunit protein L24A"
/protein_id="NP_011484.1"
/db_xref="GI:6321407"
/db_xref="SGD:S000002999"
/db_xref="GeneID:852852"
/translation="MKVEIDSFSGAKIYPGRGTLFVRGDSKIFRFQNSKSASLFKQRK
NPRRIAWTVLFRKHHKKGITEEVAKKRSRKTVKAQRPITGASLDLIKERRSLKPEVRK
ANREEKLKANKEKKKAEKAARKAEKAKSAGTQSSKFSKQQAKGAFQKVAATSR"
gene 439091..439638
/gene="RPL30"
/locus_tag="YGL030W"
/db_xref="GeneID:852853"
mRNA join(439091..439093,439324..439638)
/gene="RPL30"
/locus_tag="YGL030W"
/product="ribosomal 60S subunit protein L30"
/transcript_id="NM_001180895.1"
/db_xref="GI:296145009"
/db_xref="GeneID:852853"
CDS join(439091..439093,439324..439638)
/gene="RPL30"
/locus_tag="YGL030W"
/note="Ribosomal 60S subunit protein L30; involved in
pre-rRNA processing in the nucleolus; autoregulates
splicing of its transcript; homologous to mammalian
ribosomal protein L30, no bacterial homolog"
/codon_start=1
/product="ribosomal 60S subunit protein L30"
/protein_id="NP_011485.1"
/db_xref="GI:6321408"
/db_xref="SGD:S000002998"
/db_xref="GeneID:852853"
/translation="MAPVKSQESINQKLALVIKSGKYTLGYKSTVKSLRQGKSKLIII
AANTPVLRKSELEYYAMLSKTKVYYFQGGNNELGTAVGKLFRVGVVSILEAGDSDILT
TLA"
gene 440063..440425
/gene="CGR1"
/locus_tag="YGL029W"
/db_xref="GeneID:852854"
mRNA 440063..440425
/gene="CGR1"
/locus_tag="YGL029W"
/product="Cgr1p"
/transcript_id="NM_001180894.1"
/db_xref="GI:296145010"
/db_xref="GeneID:852854"
CDS 440063..440425
/gene="CGR1"
/locus_tag="YGL029W"
/note="Protein involved in nucleolar integrity and
processing of pre-rRNA; has a role in processing rRNA for
the 60S ribosome subunit; transcript is induced in
response to cytotoxic stress but not genotoxic stress;
relocalizes from nucleus to nucleolus upon DNA replication
stress"
/codon_start=1
/product="Cgr1p"
/protein_id="NP_011486.1"
/db_xref="GI:6321409"
/db_xref="SGD:S000002997"
/db_xref="GeneID:852854"
/translation="MVNETGESQKAAKGTPVSGKVWKAEKTPLRAKSRVVKNKKLTSW
ELKKQKRLEDKQFKERLKALKDEKEEARQAKITMLKERREKKEENERYERLAAKMHAK
KVERMRRREKRNKALKER"
gene complement(440716..440807)
/locus_tag="tF(GAA)G"
/db_xref="GeneID:852855"
tRNA complement(join(440716..440751,440771..440807))
/locus_tag="tF(GAA)G"
/product="tRNA-Phe"
/note="Phenylalanine tRNA (tRNA-Phe), predicted by
tRNAscan-SE analysis"
/db_xref="SGD:S000006565"
/db_xref="GeneID:852855"
gene complement(441281..442909)
/gene="SCW11"
/locus_tag="YGL028C"
/db_xref="GeneID:852856"
mRNA complement(441281..442909)
/gene="SCW11"
/locus_tag="YGL028C"
/product="Scw11p"
/transcript_id="NM_001180893.3"
/db_xref="GI:398364844"
/db_xref="GeneID:852856"
CDS complement(441281..442909)
/gene="SCW11"
/locus_tag="YGL028C"
/EC_number="3.2.1.-"
/note="Cell wall protein with similarity to glucanases;
may play a role in conjugation during mating based on its
regulation by Ste12p"
/codon_start=1
/product="Scw11p"
/protein_id="NP_011487.3"
/db_xref="GI:398364845"
/db_xref="SGD:S000002996"
/db_xref="GeneID:852856"
/translation="MISPISFLSSLLCLTYLTSALPILPKREVVTRVHTASTTNVVTD
FYSTTTEVVIAPTVEFLISDSVTFTTTLIPQGVNPTAEPTTTITKVLLKKAEMSTSSQ
PTSTLQPSTIPQSTSSFQAESTLQAVSTQQTAMSVSAGTSEDVQQLATTSTSISSSPS
PTTTSTSTQNIVSGVGEANVEGNTQSQHHSYQAAATSTLNQQTSTSIASQESTESTNT
PTSSSTSSSTSSSTSSSTSSSTSSSTSSSTSSSTSSSTSSTQETAATTSEGSSSSSAA
ITSSPKAIAYSPYNDDGSCKSADAVSSDLTLIKSKGISKIRVYGTDCNSFETVQPAAV
KLGIKINQGLYITSSGVDSIDDSVTTLIQYGQTNGWDVFDFITVGNEAINNGWCSVSD
LISKISSVKSKLSEAGYSGQITTSEPPVSFENNPDLCKKSDIDFVGINPHAYFDTSAS
AETAGTFVKGQVELIQGVCGTSNVFVTETGYPSSGIQNGGNIPSTANQITAVQNILNE
MDLDVTILSTYNDYWKAPGDYGIEQSFGVIEYFP"
gene complement(443642..446143)
/gene="CWH41"
/locus_tag="YGL027C"
/gene_synonym="DER7; GLS1"
/db_xref="GeneID:852857"
mRNA complement(443642..446143)
/gene="CWH41"
/locus_tag="YGL027C"
/gene_synonym="DER7; GLS1"
/product="Cwh41p"
/transcript_id="NM_001180892.1"
/db_xref="GI:296145012"
/db_xref="GeneID:852857"
CDS complement(443642..446143)
/gene="CWH41"
/locus_tag="YGL027C"
/gene_synonym="DER7; GLS1"
/EC_number="3.2.1.106"
/note="Processing alpha glucosidase I, ER type II integral
membrane N-glycoprotein involved in assembly of cell wall
beta 1,6 glucan and asparagine-linked protein
glycosylation; also involved in ER protein quality control
and sensing of ER stress"
/codon_start=1
/product="Cwh41p"
/protein_id="NP_011488.1"
/db_xref="GI:6321411"
/db_xref="SGD:S000002995"
/db_xref="GeneID:852857"
/translation="MLISKSKMFKTFWILTSIVLLASATVDISKLQEFEEYQKFTNES
LLWAPYRSNCYFGMRPRYVHESPLIMGIMWFNSLSQDGLHSLRHFATPQDKLQKYGWE
VYDPRIGGKEVFIDEKNNLNLTVYFVKSKNGENWSVRVQGEPLDPKRPSTASVVLYFS
QNGGEIDGKSSLAMIGHDGPNDMKFFGYSKELGEYHLTVKDNFGHYFKNPEYETMEVA
PGSDCSKTSHLSLQIPDKEVWKARDVFQSLVSDSIRDILEKEETKQRPADLIPSVLTI
RNLYNFNPGNFHYIQKTFDLTKKDGFQFDITYNKLGTTQSISTREQVTELITWSLNEI
NARFDKQFSFGEGPDSIESVEVKRRFALETLSNLLGGIGYFYGNQLIDRETEFDESQF
TEIKLLNAKEEGPFELFTSVPSRGFFPRGFYWDEGFHLLQIMEYDFDLAFEILASWFE
MIEDDSGWIAREIILGNEARSKVPQEFQVQNPNIANPPTLLLAFSEMLSRAIENIGDF
NSDSYHQVMFNSRTAKFMTNNLEANPGLLTEYAKKIYPKLLKHYNWFRKSQTGLIDEY
EEILEDEGIWDKIHKNEVYRWVGRTFTHCLPSGMDDYPRAQPPDVAELNVDALAWVGV
MTRSMKQIAHVLKLTQDEQRYAQIEQEVVENLDLLHWSENDNCYCDISIDPEDDEIRE
FVCHEGYVSVLPFALKLIPKNSPKLEKVVALMSDPEKIFSDYGLLSLSRQDDYFGKDE
NYWRGPIWMNINYLCLDAMRYYYPEVILDVAGEASNAKKLYQSLKINLSNNIYKVWEE
QGYCYENYSPIDGHGTGAEHFTGWTALVVNILGRF"
gene complement(446412..448535)
/gene="TRP5"
/locus_tag="YGL026C"
/db_xref="GeneID:852858"
mRNA complement(446412..448535)
/gene="TRP5"
/locus_tag="YGL026C"
/product="tryptophan synthase TRP5"
/transcript_id="NM_001180891.1"
/db_xref="GI:296145013"
/db_xref="GeneID:852858"
CDS complement(446412..448535)
/gene="TRP5"
/locus_tag="YGL026C"
/EC_number="4.2.1.20"
/note="Tryptophan synthase, catalyzes the last step of
tryptophan biosynthesis; regulated by the general control
system of amino acid biosynthesis"
/codon_start=1
/product="tryptophan synthase TRP5"
/protein_id="NP_011489.1"
/db_xref="GI:6321412"
/db_xref="SGD:S000002994"
/db_xref="GeneID:852858"
/translation="MSEQLRQTFANAKKENRNALVTFMTAGYPTVKDTVPILKGFQDG
GVDIIELGMPFSDPIADGPTIQLSNTVALQNGVTLPQTLEMVSQARNEGVTVPIILMG
YYNPILNYGEERFIQDAAKAGANGFIIVDLPPEEALKVRNYINDNGLSLIPLVAPSTT
DERLELLSHIADSFVYVVSRMGTTGVQSSVASDLDELISRVRKYTKDTPLAVGFGVST
REHFQSVGSVADGVVIGSKIVTLCGDAPEGKRYDVAKEYVQGILNGAKHKVLSKDEFF
AFQKESLKSANVKKEILDEFDENHKHPIRFGDFGGQYVPEALHACLRELEKGFDEAVA
DPTFWEDFKSLYSYIGRPSSLHKAERLTEHCQGAQIWLKREDLNHTGSHKINNALAQV
LLAKRLGKKNVIAETGAGQHGVATATACAKFGLTCTVFMGAEDVRRQALNVFRMRILG
AKVIAVTNGTKTLRDATSEAFRFWVTNLKTTYYVVGSAIGPHPYPTLVRTFQSVIGKE
TKEQFAAMNNGKLPDAVVACVGGGSNSTGMFSPFEHDTSVKLLGVEAGGDGVDTKFHS
ATLTAGRPGVFHGVKTYVLQDSDGQVHDTHSVSAGLDYPGVGPELAYWKSTGRAQFIA
ATDAQALLGFKLLSQLEGIIPALESSHAVYGACELAKTMKPDQHLVINISGRGDKDVQ
SVAEVLPKLGPKIGWDLRFEEDPSA"
gene complement(448764..449957)
/gene="PGD1"
/locus_tag="YGL025C"
/gene_synonym="HRS1; MED3"
/db_xref="GeneID:852860"
mRNA complement(448764..449957)
/gene="PGD1"
/locus_tag="YGL025C"
/gene_synonym="HRS1; MED3"
/product="Pgd1p"
/transcript_id="NM_001180890.1"
/db_xref="GI:296145014"
/db_xref="GeneID:852860"
CDS complement(448764..449957)
/gene="PGD1"
/locus_tag="YGL025C"
/gene_synonym="HRS1; MED3"
/note="Subunit of the RNA polymerase II mediator complex;
associates with core polymerase subunits to form the RNA
polymerase II holoenzyme; essential for basal and
activated transcription; direct target of Cyc8p-Tup1p
transcriptional corepressor"
/codon_start=1
/product="Pgd1p"
/protein_id="NP_011490.2"
/db_xref="GI:37362652"
/db_xref="SGD:S000002993"
/db_xref="GeneID:852860"
/translation="MDSIIPAGVKLDDLQVILAKNENETRDKVCKQINEARDEILPLR
LQFNEFIQIMANIDQEGSKQADRMAKYLHIRDKILQLNDRFQTLSSHLEALQPLFSTV
PEYLKTADNRDRSFQLLEPLSTYNKNGNAVCSTATVVSTNHSAAASTPTTTATPHANP
ITHAHSLSNPNSTATMQHNPLAGKRGPKSGSTMGTPTVHNSTAAAPIAAPKKPRKPRQ
TKKAKAQAQAQAQAQAQVYAQQSTVQTPITASMAAALPNPTPSMINSVSPTNVMGTPL
TNMMSPMGNAYSMGAQNQGGQVSMSQFNGSGNGSNPNTNTNSNNTPLQSQLNLNNLTP
ANILNMSMNNDFQQQQQQQQQQQQPQPQYNMNMGMNNMNNGGKELDSLDLNNLELGGL
NMDFL"
gene complement(450197..452104)
/gene="PIB2"
/locus_tag="YGL023C"
/db_xref="GeneID:852861"
mRNA complement(450197..452104)
/gene="PIB2"
/locus_tag="YGL023C"
/product="Pib2p"
/transcript_id="NM_001180888.3"
/db_xref="GI:398364864"
/db_xref="GeneID:852861"
CDS complement(450197..452104)
/gene="PIB2"
/locus_tag="YGL023C"
/note="hypothetical protein; contains FYVE domain; similar
to Fab1 and Vps27"
/codon_start=1
/product="Pib2p"
/protein_id="NP_011492.3"
/db_xref="GI:398364865"
/db_xref="SGD:S000002991"
/db_xref="GeneID:852861"
/translation="MTALHSVSKTPAIKEEEEDGDERDGRGVPLGPRNHDYRGRKGDE
ESGADTVTSPITFEKKKIAPRASTHSEQSILSSISLKSMVNQHRQQQLQQESSTGAGT
GFVDRKQQIQSPAMVSILRKNSAEENVRSSHSSKLGEGQIDGRKASASKEIGKTLPFT
DDQRSNPELDPTNSVVDVSRGKNTKSKTVFNELEDDADDDDEVRQKNLTTQALRKLSS
FKMNASSNLRLSKENKAKESSSSSTSSVSSSSTSKVENIVDKLTTTNSSSMSQLRFGN
TNVIIDSVNHAAKPPHQQMLRKPSLEFLPQPASSTNLNFNSNKHKSNVRQISNPKKPL
YIPAVLRKVSETNITNDDLLNATLSSYYKKASNLEHGFNPSKSQSASVQNANNLRIIS
SQSSVQSNTSSILESYKNKISSYLFPNSIPNSDRINLIPTISNRNSARVNPPTKDHWI
PDSKRNSCRYCHKPFTLWERKHHCRHCGDIFCQDHLRHWLYLDSQANFIMINELNNGG
INGGGTLCKICDDCLVEYENLSTTNHNANTNEDNINVEEGEDDDNDNRKKLRNYYKNR
QMNALFRPKKGGSSQEHATVDRDTTTPIQVKSNDEEADNENTGGEQEEGNDVLGSVIG
SVPANWNWSSF"
gene 452404..454560
/gene="STT3"
/locus_tag="YGL022W"
/db_xref="GeneID:852862"
mRNA 452404..454560
/gene="STT3"
/locus_tag="YGL022W"
/product="Stt3p"
/transcript_id="NM_001180887.1"
/db_xref="GI:296145016"
/db_xref="GeneID:852862"
CDS 452404..454560
/gene="STT3"
/locus_tag="YGL022W"
/EC_number="2.4.99.18"
/note="Subunit of the oligosaccharyltransferase complex of
the ER lumen, which catalyzes asparagine-linked
glycosylation of newly synthesized proteins; forms a
subcomplex with Ost3p and Ost4p and is directly involved
in catalysis"
/codon_start=1
/product="Stt3p"
/protein_id="NP_011493.1"
/db_xref="GI:6321416"
/db_xref="SGD:S000002990"
/db_xref="GeneID:852862"
/translation="MGSDRSCVLSVFQTILKLVIFVAIFGAAISSRLFAVIKFESIIH
EFDPWFNYRATKYLVNNSFYKFLNWFDDRTWYPLGRVTGGTLYPGLMTTSAFIWHALR
NWLGLPIDIRNVCVLFAPLFSGVTAWATYEFTKEIKDASAGLLAAGFIAIVPGYISRS
VAGSYDNEAIAITLLMVTFMFWIKAQKTGSIMHATCAALFYFYMVSAWGGYVFITNLI
PLHVFLLILMGRYSSKLYSAYTTWYAIGTVASMQIPFVGFLPIRSNDHMAALGVFGLI
QIVAFGDFVKGQISTAKFKVIMMVSLFLILVLGVVGLSALTYMGLIAPWTGRFYSLWD
TNYAKIHIPIIASVSEHQPVSWPAFFFDTHFLIWLFPAGVFLLFLDLKDEHVFVIAYS
VLCSYFAGVMVRLMLTLTPVICVSAAVALSKIFDIYLDFKTSDRKYAIKPAALLAKLI
VSGSFIFYLYLFVFHSTWVTRTAYSSPSVVLPSQTPDGKLALIDDFREAYYWLRMNSD
EDSKVAAWWDYGYQIGGMADRTTLVDNNTWNNTHIAIVGKAMASPEEKSYEILKEHDV
DYVLVIFGGLIGFGGDDINKFLWMIRISEGIWPEEIKERDFYTAEGEYRVDARASETM
RNSLLYKMSYKDFPQLFNGGQATDRVRQQMITPLDVPPLDYFDEVFTSENWMVRIYQL
KKDDAQGRTLRDVGELTRSSTKTRRSIKRPELGLRV"
gene 454785..457067
/gene="ALK1"
/locus_tag="YGL021W"
/db_xref="GeneID:852863"
mRNA 454785..457067
/gene="ALK1"
/locus_tag="YGL021W"
/product="Alk1p"
/transcript_id="NM_001180886.1"
/db_xref="GI:296145017"
/db_xref="GeneID:852863"
CDS 454785..457067
/gene="ALK1"
/locus_tag="YGL021W"
/EC_number="2.7.11.1"
/note="Protein kinase; accumulation and phosphorylation
are periodic during the cell cycle; phosphorylated in
response to DNA damage; contains characteristic motifs for
degradation via the APC pathway; ALK1 has a paralog, ALK2,
that arose from the whole genome duplication; similar to
mammalian haspins"
/codon_start=1
/product="Alk1p"
/protein_id="NP_011494.1"
/db_xref="GI:6321417"
/db_xref="SGD:S000002989"
/db_xref="GeneID:852863"
/translation="MLLHFDIVIQLLSSHTLKSHQVEPPMDFETSFEEFVEDKRFIAL
EVSDNDDDCDTDLTADTADELESSAILKMRESDASLNVTTGNNTSRKTTSNSKKRWSL
LSNHSAVSSSKSKKRWSVLSSSFTSESHKDRESRNVLQQKRKSLQSYSSLDTVASNSS
ISASSSLKRSSTGLSLRQLFTKIGINDDISQPGIGIPQGKENLPPTMGKKNSSIASTS
SENRLRTPLKPLVNHSKRPTSQPQQQQPLYNASLSSRRSSISSTVSSSSSSKWRFWKR
NKNQTPALLQPDHHSLKTFPAVNRRDSMTPVEPRNMVKHKTSFSDFHKTIFSSNTYSE
SSDTISSMEITLKNKASSSSLSLNVLKKRNSQSSLKHKSSHASLQKFKRNKGKSSMIA
PSTATNSSNDDSCSYSSKNSTLSHRISLPVPDQVSRDKIQNKLRYSTSLLSLNSKSSL
PMNKNDHDETLLRQILLNCDIKRILNPAKGDVLPLINDVNHLSSIQLTSNVWQIGEVI
CKKVSLGTIDDITWDRKFLSLQELEKLKIMQQKFDGIPQLLKSFVVKEANGGLYLYLL
FKDHGTPISLISLKNWKQILKIFWSCAGIIHGLEKNLKFEHRNLTLDNILIDGNGNIT
IIDFKCSRLQTPQDDVLYLRLDHPLFFLNGKDKSKINEYQYQFEFEIYQSMRILLNMD
ASAFEPMTNLYWLYYLSRVLLKFGDRKLGKNDANRDKMARVINHLEMNLAVHKRGGQL
FKRLETEDIKNTGDLLKLYK"
gene complement(457163..457870)
/gene="GET1"
/locus_tag="YGL020C"
/gene_synonym="MDM39"
/db_xref="GeneID:852864"
mRNA complement(457163..457870)
/gene="GET1"
/locus_tag="YGL020C"
/gene_synonym="MDM39"
/product="Get1p"
/transcript_id="NM_001180885.1"
/db_xref="GI:296145018"
/db_xref="GeneID:852864"
CDS complement(457163..457870)
/gene="GET1"
/locus_tag="YGL020C"
/gene_synonym="MDM39"
/note="Subunit of the GET complex; involved in insertion
of proteins into the ER membrane; required for the
retrieval of HDEL proteins from the Golgi to the ER in an
ERD2 dependent fashion and for normal mitochondrial
morphology and inheritance"
/codon_start=1
/product="Get1p"
/protein_id="NP_011495.1"
/db_xref="GI:6321418"
/db_xref="SGD:S000002988"
/db_xref="GeneID:852864"
/translation="MHWAAAVAIFFIVVTKFLQYTNKYHEKWISKFAPGNELSKKYLA
KVKERHELKEFNNSISAQDNYAKWTKNNRKLDSLDKEINNLKDEIQSENKAFQAHLHK
LRLLALTVPFFVFKIMYGKTPVYKLSSSTSTLFPTFVSGVWSQGWLYVLLHPLRTISQ
KWHIMEGKFGASKFDDMALQSVSLGIWVWALMNVINGVEFIVKQLFLTPKMEAPASVE
TQEEKALDAVDDAIILD"
gene 458156..458992
/gene="CKB1"
/locus_tag="YGL019W"
/db_xref="GeneID:852865"
mRNA 458156..458992
/gene="CKB1"
/locus_tag="YGL019W"
/product="Ckb1p"
/transcript_id="NM_001180884.3"
/db_xref="GI:398364886"
/db_xref="GeneID:852865"
CDS 458156..458992
/gene="CKB1"
/locus_tag="YGL019W"
/note="Beta regulatory subunit of casein kinase 2 (CK2), a
Ser/Thr protein kinase with roles in cell growth and
proliferation; CK2, comprised of CKA1, CKA2, CKB1 and
CKB2, has many substrates including transcription factors
and all RNA polymerases"
/codon_start=1
/product="Ckb1p"
/protein_id="NP_011496.3"
/db_xref="GI:398364887"
/db_xref="SGD:S000002987"
/db_xref="GeneID:852865"
/translation="MSQEFVEDYSRTGSSDDEDSGAYDEWIPSFCSRFGHEYFCQVPT
EFIEDDFNMTSLSQEVPHYRKALDLILDLEAMSDEEEDEDDVVEEDEVDQEMQSNDGH
DEGKRRNKSPVVNKSIIEHAAEQLYGLIHARFILTKPGLQAMAEKFDHKEFGTCPRYY
CNGMQLLPCGLSDTVGKHTVRLYCPSCQDLYLPQSSRFLCLEGAFWGTSFPGVFLKHF
KELEEYVERKSKESYELKVFGFRINDEAVSGPRMKWLRQYPSTEEDWEEFAKCEFETP
AV"
gene complement(459110..459664)
/gene="JAC1"
/locus_tag="YGL018C"
/db_xref="GeneID:852866"
mRNA complement(459110..459664)
/gene="JAC1"
/locus_tag="YGL018C"
/product="Jac1p"
/transcript_id="NM_001180883.1"
/db_xref="GI:296145020"
/db_xref="GeneID:852866"
CDS complement(459110..459664)
/gene="JAC1"
/locus_tag="YGL018C"
/note="Specialized J-protein that functions with Hsp70 in
Fe-S cluster biogenesis in mitochondria, involved in iron
metabolism; contains a J domain typical to J-type
chaperones; localizes to the mitochondrial matrix"
/codon_start=1
/product="Jac1p"
/protein_id="NP_011497.1"
/db_xref="GI:6321420"
/db_xref="SGD:S000002986"
/db_xref="GeneID:852866"
/translation="MLKYLVQRRFTSTFYELFPKTFPKKLPIWTIDQSRLRKEYRQLQ
AQHHPDMAQQGSEQSSTLNQAYHTLKDPLRRSQYMLKLLRNIDLTQEQTSNEVTTSDP
QLLLKVLDIHDELSQMDDEAGVKLLEKQNKERIQDIEAQLGQCYNDKDYAAAVKLTVE
LKYWYNLAKAFKDWAPGKQLEMNH"
gene 459854..461365
/gene="ATE1"
/locus_tag="YGL017W"
/db_xref="GeneID:852867"
mRNA 459854..461365
/gene="ATE1"
/locus_tag="YGL017W"
/product="Ate1p"
/transcript_id="NM_001180882.1"
/db_xref="GI:296145021"
/db_xref="GeneID:852867"
CDS 459854..461365
/gene="ATE1"
/locus_tag="YGL017W"
/EC_number="2.3.2.8"
/note="Arginyl-tRNA-protein transferase, catalyzes
post-translational conjugation of arginine to the amino
termini of acceptor proteins which are then subject to
degradation via the N-end rule pathway"
/codon_start=1
/product="Ate1p"
/protein_id="NP_011498.1"
/db_xref="GI:6321421"
/db_xref="SGD:S000002985"
/db_xref="GeneID:852867"
/translation="MSDRFVIWAPSMHNEPAAKCGYCHGNKGGNMDQLFALDSWAHRY
MNKMDVVKIENCTIGSFVEHMDVATYDRMCNMGFRRSGKFLYKVDPLRNCCRLYTIRT
APQELNMTKELKKCISRFATRITSEDYCPAAVASSDFVGKIVNAEMNSKTFYTRFEPA
LYSEEKYHLFVKYQEKVHQDYNNSPKSFKRFLCDTPFGPEAVLGTQESWEQLNNWQRM
KPGEKLKHMGPVHECYYYEGKLIAITVSDILPSGISSVYFIWDPDYSKWSLGKLSALR
DLAIIQRTNLQYYYLGYYIEDCPKMNYKANYGAEVLDVCHSKYIPLKPIQDMISRGKL
FVIGEEETKVTKELYLVDSETGRGEGFPTDNVVKYKNIAEEIYGVGGCAFKSANESAL
ELKELYGIPYEEEDLDTIYHLKEHNGHAPNGIPNVVPGLLPLWELLDIMQSGKITDLE
GRLFLFEIETEGIRPLINFYSEPPNVKKRICDVIRLFGFETCMKAVILYSEQM"
gene 461666..464911
/gene="KAP122"
/locus_tag="YGL016W"
/gene_synonym="PDR6"
/db_xref="GeneID:852868"
mRNA 461666..464911
/gene="KAP122"
/locus_tag="YGL016W"
/gene_synonym="PDR6"
/product="Kap122p"
/transcript_id="NM_001180881.1"
/db_xref="GI:296145022"
/db_xref="GeneID:852868"
CDS 461666..464911
/gene="KAP122"
/locus_tag="YGL016W"
/gene_synonym="PDR6"
/note="Karyopherin beta, responsible for import of the
Toa1p-Toa2p complex into the nucleus; binds to
nucleoporins Nup1p and Nup2p; may play a role in
regulation of pleiotropic drug resistance"
/codon_start=1
/product="Kap122p"
/protein_id="NP_011499.1"
/db_xref="GI:6321422"
/db_xref="SGD:S000002984"
/db_xref="GeneID:852868"
/translation="MSSIHEVVALIEELYSPHPKHDVNQIQQSLQSIQKSEQGFHLAN
ELLSDDKYSANVKYFGALTLTVQLNTRGENDYETLWNVFRSNLLYLTKFSTLYVSNPN
MYGQSLIIIKKLMSNLSLIFTKINDPQLNNAGNENMIKQWNNPINTFIQLMSVQNQNI
NADQLLLDSINCSLTYEQLSQFVSLSQKHNELALTFTEVIVEDLTKFQTKRHSMSQIH
EVVHEHLYISTMALINLNLTAQAVFNPTVFDCITAWINYISLTRSVSSSGRMDLSEIF
QNLIDLMYQSTEGSDGYENAEKILTIFGNVFANDPLLMSYDLRQQIECIFLGVVRPDS
GITDISNKNSWMLQYMNYLVTNDFFSELKELAICIVDFLQINTLSVCNKLFTNIQAAD
NGQVQDEYIQEYIKVLLQMTNFPLTPVLQEFFSVRMVDFWLDLSDAYTNLASETLRPN
SIELSTQIFQQLINIYLPKISLSVKQRIIEEEGESTSVNEFEDFRNAVSDLAQSLWSI
LGNDNLTNVLIDGMGQMPAASDETLIIKDTDVLFRIETMCFVLNTILVDMTLSESPWI
KNIVDANKFFNQNVISVFQTGFQTSASTKVSQILKLDFVRTSTTLIGTLAGYFKQEPF
QLNPYVEALFQGLHTCTNFTSKNEQEKISNDKLEVMVIKTVSTLCETCREELTPYLMH
FISFLNTVIMPDSNVSHFTRTKLVRSIGYVVQCQVSNGPEEQAKYILQLTNLLSGSIE
HCLASSVQLQEQQDYINCLLYCISELATSLIQPTEIIENDALLQRLSEFQSFWSSDPL
QIRSKIMCTIDKVLDNSIYCKNSAFVEIGCLIVGKGLNLPDGEPYFLKYNMSEVMNFV
LRHVPNCELATCLPYFVYLLEKLISEFRKELTPQEFDFMFEKILLVYYDAYIINDPDL
LQMTIGFVNNVLDVKPGLAIGSKHWTSFILPQFLKLIPSREKFTIVAVAKFWTKLINN
KKYNQEELTTVRQQVSSIGGDLVYQIMYGLFHTQRSDLNSYTDLLRALVAKFPIEARE
WLVAVLPQICNNPAGHEKFINKLLITRGSRAAGNVILQWWLDCTTLPNYQG"
gene complement(465043..465435)
/locus_tag="YGL015C"
/db_xref="GeneID:852869"
mRNA complement(465043..465435)
/locus_tag="YGL015C"
/product="hypothetical protein"
/transcript_id="NM_001180880.3"
/db_xref="GI:398364908"
/db_xref="GeneID:852869"
CDS complement(465043..465435)
/locus_tag="YGL015C"
/note="hypothetical protein; null mutants accumulate cargo
in the Golgi"
/codon_start=1
/product="hypothetical protein"
/protein_id="NP_011500.3"
/db_xref="GI:398364909"
/db_xref="SGD:S000002983"
/db_xref="GeneID:852869"
/translation="MEDTIRPLNYADIETSGPINLLETTNNLKSSLKKFSQKAKGSHI
SRERIHHFRKWKNKTESLSENHLKPPPDVDSLCFSNCFQPDALSGNVFLPPRSSNMYW
NEKQLQLEMEILKFLSLNTSNECCTSDD"
gene 466141..468807
/gene="PUF4"
/locus_tag="YGL014W"
/gene_synonym="YGL023"
/db_xref="GeneID:852870"
mRNA 466141..468807
/gene="PUF4"
/locus_tag="YGL014W"
/gene_synonym="YGL023"
/product="Puf4p"
/transcript_id="NM_001180879.1"
/db_xref="GI:296145024"
/db_xref="GeneID:852870"
CDS 466141..468807
/gene="PUF4"
/locus_tag="YGL014W"
/gene_synonym="YGL023"
/note="Member of the PUF protein family, which is defined
by the presence of Pumilio homology domains that confer
RNA binding activity; preferentially binds mRNAs encoding
nucleolar ribosomal RNA-processing factors"
/codon_start=1
/product="Puf4p"
/protein_id="NP_011501.1"
/db_xref="GI:6321424"
/db_xref="SGD:S000002982"
/db_xref="GeneID:852870"
/translation="MSTKGLKEEIDDVPSVDPVVSETVNSALEQLQLDDPEENATSNA
FANKVSQDSQFANGPPSQMFPHPQMMGGMGFMPYSQMMQVPHNPCPFFPPPDFNDPTA
PLSSSPLNAGGPPMLFKNDSLPFQMLSSGAAVATQGGQNLNPLINDNSMKVLPIASAD
PLWTHSNVPGSASVAIEETTATLQESLPSKGRESNNKASSFRRQTFHALSPTDLINAA
NNVTLSKDFQSDMQNFSKAKKPSVGANNTAKTRTQSISFDNTPSSTSFIPPTNSVSEK
LSDFKIETSKEDLINKTAPAKKESPTTYGAAYPYGGPLLQPNPIMPGHPHNISSPIYG
IRSPFPNSYEMGAQFQPFSPILNPTSHSLNANSPIPLTQSPIHLAPVLNPSSNSVAFS
DMKNDGGKPTTDNDKAGPNVRMDLINPNLGPSMQPFHILPPQQNTPPPPWLYSTPPPF
NAMVPPHLLAQNHMPLMNSANNKHHGRNNNSMSSHNDNDNIGNSNYNNKDTGRSNVGK
MKNMKNSYHGYYNNNNNNNNNNNNNNNSNATNSNSAEKQRKIEESSRFADAVLDQYIG
SIHSLCKDQHGCRFLQKQLDILGSKAADAIFEETKDYTVELMTDSFGNYLIQKLLEEV
TTEQRIVLTKISSPHFVEISLNPHGTRALQKLIECIKTDEEAQIVVDSLRPYTVQLSK
DLNGNHVIQKCLQRLKPENFQFIFDAISDSCIDIATHRHGCCVLQRCLDHGTTEQCDN
LCDKLLALVDKLTLDPFGNYVVQYIITKEAEKNKYDYTHKIVHLLKPRAIELSIHKFG
SNVIEKILKTAIVSEPMILEILNNGGETGIQSLLNDSYGNYVLQTALDISHKQNDYLY
KRLSEIVAPLLVGPIRNTPHGKRIIGMLHLDS"
gene complement(469092..472298)
/gene="PDR1"
/locus_tag="YGL013C"
/gene_synonym="AMY1; ANT1; BOR2; CYH3; NRA2; SMR2; TIL1;
TPE1; TPE3"
/db_xref="GeneID:852871"
mRNA complement(469092..472298)
/gene="PDR1"
/locus_tag="YGL013C"
/gene_synonym="AMY1; ANT1; BOR2; CYH3; NRA2; SMR2; TIL1;
TPE1; TPE3"
/product="Pdr1p"
/transcript_id="NM_001180878.1"
/db_xref="GI:296145025"
/db_xref="GeneID:852871"
CDS complement(469092..472298)
/gene="PDR1"
/locus_tag="YGL013C"
/gene_synonym="AMY1; ANT1; BOR2; CYH3; NRA2; SMR2; TIL1;
TPE1; TPE3"
/note="Transcription factor that regulates the pleiotropic
drug response; zinc cluster protein that is a master
regulator involved in recruiting other zinc cluster
proteins to pleiotropic drug response elements (PDREs) to
fine tune the regulation of multidrug resistance genes;
PDR1 has a paralog, PDR3, that arose from the whole genome
duplication"
/codon_start=1
/product="Pdr1p"
/protein_id="NP_011502.1"
/db_xref="GI:6321425"
/db_xref="SGD:S000002981"
/db_xref="GeneID:852871"
/translation="MRGLTPKNGVHIETGPDTESSADSSNFSTGFSGKIRKPRSKVSK
ACDNCRKRKIKCNGKFPCASCEIYSCECTFSTRQGGARIKNLHKTSLEGTTVQVKEET
DSSSTSFSNPQRCTDGPCAVEQPTKFFENFKLGGRSSGDNSGSDGKNDDDVNRNGFYE
DDSESQATLTSLQTTLKNLKEMAHLGTHVTSAIESIELQISDLLKRWEPKVRTKELAT
TKFYPNKSIETQLMKNKYCDVVHLTRYAAWSNNKKDQDTSSQPLIDEIFGLYSPFQFL
SLQGIGKCFQNYRSKSKCEIFPRTAKETIYIMLRFFDVCFHHINQGCVSIANPLENYL
QKMNLLPSTPSSISSAGSPNTAHTKSHVALVINHLPQPFVRNITGISNSELLSEMNND
ISMFGILLKMLDMHKNSYQNFLMEITSNPSVAKNTQSIDVLQEFIHYCQAGEALIALC
YSYYNSTLYNYVDFTCDITHLEQLLYFLDLLFWLSEIYGFEKVLNVAVHFVSRVGLSR
WEFYVGLDENFAERRRNLWWKAFYFEKTLASKLGYPSNIDDSKINCLLPKNFRDVGFL
DNRDFIENVHLVRRSEAFDNMCISDLKYYGELAVLQIVSHFSSSVLFNEKFTSIRNTS
KPSVVREKLLFEVLEIFNETEMKYDAIKEQTGKLFDIAFSKDSTELKVSREDKIMASK
FVLFYEHHFCRMVNESDNIVARLCVHRRPSILIENLKIYLHKIYKSWTDMNKILLDFD
NDYSVYRSFAHYSISCIILVSQAFSVAEFIKVNDVVNMIRVFKRFLDIKIFSENETNE
HVFNSQSFKDYTRAFSFLTIVTRIMLLAYGESSSTNLDVISKYIDENAPDLKGIIELV
LDTNSCAYRFLLEPVQKSGFHLTVSQMLKNRKFQEPLMSNEDNKQMKHNSGKNLNPDL
PSLKTGTSCLLNGIESPQLPFNGRSAPSPVRNNSLPEFAQLPSFRSLSVSDMINPDYA
QPTNGQNNTQVQSNKPINAQQQIPTSVQVPFMNTNEINNNNNNNNNNKNNINNINNNN
SNNFSATSFNLGTLDEFVNNGDLEDLYSILWSDVYPDS"
gene 472855..474276
/gene="ERG4"
/locus_tag="YGL012W"
/db_xref="GeneID:852872"
mRNA 472855..474276
/gene="ERG4"
/locus_tag="YGL012W"
/product="delta(24(24(1)))-sterol reductase"
/transcript_id="NM_001180877.1"
/db_xref="GI:296145026"
/db_xref="GeneID:852872"
CDS 472855..474276
/gene="ERG4"
/locus_tag="YGL012W"
/EC_number="1.3.1.71"
/note="C-24(28) sterol reductase, catalyzes the final step
in ergosterol biosynthesis; mutants are viable, but lack
ergosterol"
/codon_start=1
/product="delta(24(24(1)))-sterol reductase"
/protein_id="NP_011503.1"
/db_xref="GI:6321426"
/db_xref="SGD:S000002980"
/db_xref="GeneID:852872"
/translation="MAKDNSEKLQVQGEEKKSKQPVNFLPQGKWLKPNEIEYEFGGTT
GVIGMLIGFPLLMYYMWICAEFYHGKVALPKAGESWMHFIKHLYQLVLENGIPEKYDW
TIFLTFWVFQIIFYYTLPGIWTKGQPLSHLKGKQLPYFCNAMWTLYVTTTLVLVLHFT
NLFRLYVIIDRFGRIMTCAIISGFAFSIILYLWTLFISHDYHRMTGNHLYDFFMGAPL
NPRWGILDLKMFFEVRLPWFTLYFITLGACLKQWETYGYVTPQLGVVMLAHWLYANAC
AKGEELIVPTWDMAYEKFGFMLIFWNIAGVPYTYCHCTLYLYYHDPSEYHWSTLYNVS
LYVVLLCAYYFFDTANAQKNAFRKQMSGDKTGRKTFPFLPYQILKNPKYMVTSNGSYL
LIDGWYTLARKIHYTADWTQSLVWALSCGFNSVFPWFFPVFFLVVLIHRAFRDQAKCK
RKYGKDWDEYCKHCPYVFIPYVF"
gene complement(474489..475247)
/gene="SCL1"
/locus_tag="YGL011C"
/gene_synonym="PRC2"
/db_xref="GeneID:852873"
mRNA complement(474489..475247)
/gene="SCL1"
/locus_tag="YGL011C"
/gene_synonym="PRC2"
/product="proteasome core particle subunit alpha 1"
/transcript_id="NM_001180876.3"
/db_xref="GI:398364932"
/db_xref="GeneID:852873"
CDS complement(474489..475247)
/gene="SCL1"
/locus_tag="YGL011C"
/gene_synonym="PRC2"
/EC_number="3.4.25.1"
/note="Alpha 1 subunit of the 20S proteasome involved in
the degradation of ubiquitinated substrates; 20S
proteasome is the core complex of the 26S proteasome;
essential for growth; detected in the mitochondria"
/codon_start=1
/product="proteasome core particle subunit alpha 1"
/protein_id="NP_011504.3"
/db_xref="GI:398364933"
/db_xref="SGD:S000002979"
/db_xref="GeneID:852873"
/translation="MSGAAAASAAGYDRHITIFSPEGRLYQVEYAFKATNQTNINSLA
VRGKDCTVVISQKKVPDKLLDPTTVSYIFCISRTIGMVVNGPIPDARNAALRAKAEAA
EFRYKYGYDMPCDVLAKRMANLSQIYTQRAYMRPLGVILTFVSVDEELGPSIYKTDPA
GYYVGYKATATGPKQQEITTNLENHFKKSKIDHINEESWEKVVEFAITHMIDALGTEF
SKNDLEVGVATKDKFFTLSAENIEERLVAIAEQD"
gene 475545..476069
/locus_tag="YGL010W"
/db_xref="GeneID:852874"
mRNA 475545..476069
/locus_tag="YGL010W"
/product="hypothetical protein"
/transcript_id="NM_001180875.1"
/db_xref="GI:296145028"
/db_xref="GeneID:852874"
CDS 475545..476069
/locus_tag="YGL010W"
/note="hypothetical protein; YGL010W is not an essential
gene"
/codon_start=1
/product="hypothetical protein"
/protein_id="NP_011505.1"
/db_xref="GI:6321428"
/db_xref="SGD:S000002978"
/db_xref="GeneID:852874"
/translation="MGEGLLDLRSQLGFYKFYHHNPKNVLIHSIFVPTILFSGSCMLH
RVKIYQSISLTAVLSVLFSIFYCLLYLPTGLLAGVLLLLLNLALIDHRVDLTFKQELG
LFTIGWIFQFVGHGVFEKRRPALIDNLVQSLVLAPYFIMFEFLFKLGFMPRLKATLEH
DLEIKQRNLRMQRQ"
gene complement(476313..478652)
/gene="LEU1"
/locus_tag="YGL009C"
/db_xref="GeneID:852875"
mRNA complement(476313..478652)
/gene="LEU1"
/locus_tag="YGL009C"
/product="3-isopropylmalate dehydratase LEU1"
/transcript_id="NM_001180874.1"
/db_xref="GI:296145029"
/db_xref="GeneID:852875"
CDS complement(476313..478652)
/gene="LEU1"
/locus_tag="YGL009C"
/EC_number="4.2.1.33"
/note="Isopropylmalate isomerase, catalyzes the second
step in the leucine biosynthesis pathway"
/codon_start=1
/product="3-isopropylmalate dehydratase LEU1"
/protein_id="NP_011506.1"
/db_xref="GI:6321429"
/db_xref="SGD:S000002977"
/db_xref="GeneID:852875"
/translation="MVYTPSKGPRTLYDKVFDAHVVHQDENGSFLLYIDRHLVHEVTS
PQAFEGLENAGRKVRRVDCTLATVDHNIPTESRKNFKSLDTFIKQTDSRLQVKTLENN
VKQFGVPYFGMSDARQGIVHTIGPEEGFTLPGTTVVCGDSHTSTHGAFGSLAFGIGTS
EVEHVLATQTIIQAKSKNMRITVNGKLSPGITSKDLILYIIGLIGTAGGTGCVIEFAG
EAIEALSMEARMSMCNMAIEAGARAGMIKPDETTFQYTKGRPLAPKGAEWEKAVAYWK
TLKTDEGAKFDHEINIEAVDVIPTITWGTSPQDALPITGSVPDPKNVTDPIKKSGMER
ALAYMGLEPNTPLKSIKVDKVFIGSCTNGRIEDLRSAAAVVRGQKLASNIKLAMVVPG
SGLVKKQAEAEGLDKIFQEAGFEWREAGCSICLGMNPDILDAYERCASTSNRNFEGRQ
GALSRTHLMSPAMAAAAGIAGHFVDIREFEYKDQDQSSPKVEVTSEDEKELESAAYDH
AEPVQPEDAPQDIANDELKDIPVKSDDTPAKPSSSGMKPFLTLEGISAPLDKANVDTD
AIIPKQFLKTIKRTGLKKGLFYEWRFRKDDQGKDQETDFVLNVEPWREAEILVVTGDN
FGCGSSREHAPWALKDFGIKSIIAPSYGDIFYNNSFKNGLLPIRLDQQIIIDKLIPIA
NKGGKLCVDLPNQKILDSDGNVLVDHFEIEPFRKHCLVNGLDDIGITLQKEEYISRYE
ALRREKYSFLEGGSKLLKFDNVPKRKAVTTTFDKVHQDW"
gene complement(479910..482666)
/gene="PMA1"
/locus_tag="YGL008C"
/gene_synonym="KTI10"
/db_xref="GeneID:852876"
mRNA complement(479910..482666)
/gene="PMA1"
/locus_tag="YGL008C"
/gene_synonym="KTI10"
/product="H(+)-exporting P2-type ATPase PMA1"
/transcript_id="NM_001180873.1"
/db_xref="GI:296145030"
/db_xref="GeneID:852876"
CDS complement(479910..482666)
/gene="PMA1"
/locus_tag="YGL008C"
/gene_synonym="KTI10"
/EC_number="3.6.3.6"
/note="Plasma membrane H+-ATPase, pumps protons out of the
cell; major regulator of cytoplasmic pH and plasma
membrane potential; P2-type ATPase; Hsp30p plays a role in
Pma1p regulation; interactions with Std1p appear to
propagate [GAR+]"
/codon_start=1
/product="H(+)-exporting P2-type ATPase PMA1"
/protein_id="NP_011507.1"
/db_xref="GI:6321430"
/db_xref="SGD:S000002976"
/db_xref="GeneID:852876"
/translation="MTDTSSSSSSSSASSVSAHQPTQEKPAKTYDDAASESSDDDDID
ALIEELQSNHGVDDEDSDNDGPVAAGEARPVPEEYLQTDPSYGLTSDEVLKRRKKYGL
NQMADEKESLVVKFVMFFVGPIQFVMEAAAILAAGLSDWVDFGVICGLLMLNAGVGFV
QEFQAGSIVDELKKTLANTAVVIRDGQLVEIPANEVVPGDILQLEDGTVIPTDGRIVT
EDCFLQIDQSAITGESLAVDKHYGDQTFSSSTVKRGEGFMVVTATGDNTFVGRAAALV
NKAAGGQGHFTEVLNGIGIILLVLVIATLLLVWTACFYRTNGIVRILRYTLGITIIGV
PVGLPAVVTTTMAVGAAYLAKKQAIVQKLSAIESLAGVEILCSDKTGTLTKNKLSLHE
PYTVEGVSPDDLMLTACLAASRKKKGLDAIDKAFLKSLKQYPKAKDALTKYKVLEFHP
FDPVSKKVTAVVESPEGERIVCVKGAPLFVLKTVEEDHPIPEDVHENYENKVAELASR
GFRALGVARKRGEGHWEILGVMPCMDPPRDDTAQTVSEARHLGLRVKMLTGDAVGIAK
ETCRQLGLGTNIYNAERLGLGGGGDMPGSELADFVENADGFAEVFPQHKYRVVEILQN
RGYLVAMTGDGVNDAPSLKKADTGIAVEGATDAARSAADIVFLAPGLSAIIDALKTSR
QIFHRMYSYVVYRIALSLHLEIFLGLWIAILDNSLDIDLIVFIAIFADVATLAIAYDN
APYSPKPVKWNLPRLWGMSIILGIVLAIGSWITLTTMFLPKGGIIQNFGAMNGIMFLQ
ISLTENWLIFITRAAGPFWSSIPSWQLAGAVFAVDIIATMFTLFGWWSENWTDIVTVV
RVWIWSIGIFCVLGGFYYEMSTSEAFDRLMNGKPMKEKKSTRSVEDFMAAMQRVSTQH
EKET"
gene complement(482941..483027)
/locus_tag="YGL007C-A"
/db_xref="GeneID:1466455"
mRNA complement(482941..483027)
/locus_tag="YGL007C-A"
/product="hypothetical protein"
/transcript_id="NM_001184592.3"
/db_xref="GI:398364962"
/db_xref="GeneID:1466455"
CDS complement(482941..483027)
/locus_tag="YGL007C-A"
/note="hypothetical protein, identified by gene-trapping,
microarray-based expression analysis, and genome-wide
homology searching; deletion exhibits slow-growth
phenotype; computationally predicted to have a role in
cell budding"
/codon_start=1
/product="hypothetical protein"
/protein_id="NP_878075.3"
/db_xref="GI:398364963"
/db_xref="SGD:S000028632"
/db_xref="GeneID:1466455"
/translation="MLPSISFDYIKRPNIVLFSNVLSLSSNI"
rep_origin 484930..485157
/note="ARS719;
Autonomously Replicating Sequence"
/db_xref="SGD:S000118459"
gene 485423..485533
/locus_tag="YGL006W-A"
/db_xref="GeneID:1466456"
mRNA 485423..485533
/locus_tag="YGL006W-A"
/product="hypothetical protein"
/transcript_id="NM_001184634.1"
/db_xref="GI:296145032"
/db_xref="GeneID:1466456"
CDS 485423..485533
/locus_tag="YGL006W-A"
/note="hypothetical protein; identified by SAGE"
/codon_start=1
/product="hypothetical protein"
/protein_id="NP_878076.1"
/db_xref="GI:33438794"
/db_xref="SGD:S000028769"
/db_xref="GeneID:1466456"
/translation="MLIFIIHYHRHLALHLMGAFQKHSNSISPPPRKGFI"
gene 485921..489442
/gene="PMC1"
/locus_tag="YGL006W"
/db_xref="GeneID:852878"
mRNA 485921..489442
/gene="PMC1"
/locus_tag="YGL006W"
/product="calcium-transporting ATPase PMC1"
/transcript_id="NM_001180871.1"
/db_xref="GI:296145033"
/db_xref="GeneID:852878"
CDS 485921..489442
/gene="PMC1"
/locus_tag="YGL006W"
/EC_number="3.6.3.8"
/note="Vacuolar Ca2+ ATPase involved in depleting cytosol
of Ca2+ ions; prevents growth inhibition by activation of
calcineurin in the presence of elevated concentrations of
calcium; similar to mammalian PMCA1a"
/codon_start=1
/product="calcium-transporting ATPase PMC1"
/protein_id="NP_011509.1"
/db_xref="GI:6321432"
/db_xref="SGD:S000002974"
/db_xref="GeneID:852878"
/translation="MSRQDENSALLANNENNKPSYTGNENGVYDNFKLSKSQLSDLHN
PKSIRSFVRLFGYESNSLFKYLKTDKNAGISLPEISNYRKTNRYKNYGDNSLPERIPK
SFLQLVWAAFNDKTMQLLTVAAVVSFVLGLYELWMQPPQYDPEGNKIKQVDWIEGVAI
MIAVFVVVLVSAANDYQKELQFAKLNKKKENRKIIVIRNDQEILISIHHVLVGDVISL
QTGDVVPADCVMISGKCEADESSITGESNTIQKFPVDNSLRDFKKFNSIDSHNHSKPL
DIGDVNEDGNKIADCMLISGSRILSGLGRGVITSVGINSVYGQTMTSLNAEPESTPLQ
LHLSQLADNISVYGCVSAIILFLVLFTRYLFYIIPEDGRFHDLDPAQKGSKFMNIFIT
SITVIVVAVPEGLPLAVTLALAFATTRMTKDGNLVRVLRSCETMGSATAVCSDKTGTL
TENVMTVVRGFPGNSKFDDSKSLPVSEQRKLNSKKVFEENCSSSLRNDLLANIVLNST
AFENRDYKKNDKNTNGSKNMSKNLSFLDKCKSRLSFFKKGNREDDEDQLFKNVNKGRQ
EPFIGSKTETALLSLARLSLGLQPGELQYLRDQPMEKFNIEKVVQTIPFESSRKWAGL
VVKYKEGKNKKPFYRFFIKGAAEIVSKNCSYKRNSDDTLEEINEDNKKETDDEIKNLA
SDALRAISVAHKDFCECDSWPPEQLRDKDSPNIAALDLLFNSQKGLILDGLLGIQDPL
RAGVRESVQQCQRAGVTVRMVTGDNILTAKAIARNCAILSTDISSEAYSAMEGTEFRK
LTKNERIRILPNLRVLARSSPEDKRLLVETLKGMGDVVAVTGDGTNDAPALKLADVGF
SMGISGTEVAREASDIILMTDDFSAIVNAIKWGRCVSVSIKKFIQFQLIVNITAVILT
FVSSVASSDETSVLTAVQLLWINLIMDTLAALALATDKPDPNIMDRKPRGRSTSLISV
STWKMILSQATLQLIVTFILHFYGPELFFKKHEDEITSHQQQQLNAMTFNTFVWLQFF
TMLVSRKLDEGDGISNWRGRISAANLNFFQDLGRNYYFLTIMAIIGSCQVLIMFFGGA
PFSIARQTKSMWITAVLCGMLSLIMGVLVRICPDEVAVKVFPAAFVQRFKYVFGLEFL
RKNHTGKHDDEEALLEESDSPESTAFY"
gene complement(489708..490547)
/gene="COG7"
/locus_tag="YGL005C"
/gene_synonym="COD5"
/db_xref="GeneID:852879"
mRNA complement(489708..490547)
/gene="COG7"
/locus_tag="YGL005C"
/gene_synonym="COD5"
/product="Cog7p"
/transcript_id="NM_001180870.1"
/db_xref="GI:296145034"
/db_xref="GeneID:852879"
CDS complement(489708..490547)
/gene="COG7"
/locus_tag="YGL005C"
/gene_synonym="COD5"
/note="Component of the conserved oligomeric Golgi complex
(Cog1p through Cog8p), a cytosolic tethering complex that
functions in protein trafficking to mediate fusion of
transport vesicles to Golgi compartments"
/codon_start=1
/product="Cog7p"
/protein_id="NP_011510.1"
/db_xref="GI:6321433"
/db_xref="SGD:S000002973"
/db_xref="GeneID:852879"
/translation="MVELTITGDDDDILSMFFDEEFVPHAFVDILLSNALNEDQIQTQ
SVSSLLLTRLDFYTKNLTKELESTIWNLDKLSQTLPRTWASSRYHKEAEQNDSSLYST
ESLKSSKLEYYLDTLASAVRALETGMHNVTEKLSDLDNENNRNTNVRQQLQSLMLIKE
RIEKVVYYLEQVRTVTNISTVRENNTTSTGTDLSITDFRTSLKALEDTIDESLSSAID
NEAKDETNKDLIGRIDSLSELKCLFKGLDKFFAEYSNFSESIKSKAQSYLSTKNIDDG
MIS"
gene complement(490703..491956)
/gene="RPN14"
/locus_tag="YGL004C"
/db_xref="GeneID:852880"
mRNA complement(490703..491956)
/gene="RPN14"
/locus_tag="YGL004C"
/product="Rpn14p"
/transcript_id="NM_001180869.3"
/db_xref="GI:398364992"
/db_xref="GeneID:852880"
CDS complement(490703..491956)
/gene="RPN14"
/locus_tag="YGL004C"
/note="Proteasome-interacting protein involved in the
assembly of the base subcomplex of the 19S proteasome
regulatory particle (RP); null mutants accumulate
ubiquitinated Gcn4p and display decreased 26S proteasome
stability; interacts with Rpt5p"
/codon_start=1
/product="Rpn14p"
/protein_id="NP_011511.3"
/db_xref="GI:398364993"
/db_xref="SGD:S000002972"
/db_xref="GeneID:852880"
/translation="MTKTITVAHIQYDFKAVLEENDENDDEFYINVDKNLNEIKEHKI
VVLGNSRGVDAGKGNTFEKVGSHLYKARLDGHDFLFNTIIRDGSKMLKRADYTAVDTA
KLQMRRFILGTTEGDIKVLDSNFNLQREIDQAHVSEITKLKFFPSGEALISSSQDMQL
KIWSVKDGSNPRTLIGHRATVTDIAIIDRGRNVLSASLDGTIRLWECGTGTTIHTFNR
KENPHDGVNSIALFVGTDRQLHEISTSKKNNLEFGTYGKYVIAGHVSGVITVHNVFSK
EQTIQLPSKFTCSCNSLTVDGNNANYIYAGYENGMLAQWDLRSPECPVGEFLINEGTP
INNVYFAAGALFVSSGFDTSIKLDIISDPESERPAIEFETPTFLVSNDDEVSQFCYVS
DDESNGEVLEVGKNNFCALYNLSNP"
gene complement(492474..494174)
/gene="CDH1"
/locus_tag="YGL003C"
/gene_synonym="HCT1"
/db_xref="GeneID:852881"
mRNA complement(492474..494174)
/gene="CDH1"
/locus_tag="YGL003C"
/gene_synonym="HCT1"
/product="Cdh1p"
/transcript_id="NM_001180868.1"
/db_xref="GI:296145036"
/db_xref="GeneID:852881"
CDS complement(492474..494174)
/gene="CDH1"
/locus_tag="YGL003C"
/gene_synonym="HCT1"
/note="Cell-cycle regulated activator of the
anaphase-promoting complex/cyclosome (APC/C), which
directs ubiquitination of cyclins resulting in mitotic
exit; targets the APC/C to specific substrates including
Cdc20p, Ase1p, Cin8p and Fin1p"
/codon_start=1
/product="Cdh1p"
/protein_id="NP_011512.1"
/db_xref="GI:6321435"
/db_xref="SGD:S000002971"
/db_xref="GeneID:852881"
/translation="MSTNLNPFMNNTPSSSPLKGSESKRVSKRPISSSSSASLLSSPS
RRSRPSTVYGDRYIPSRTDIDFNSIVSISSMASVPALNPSSTEDQVEYQKERQAHETY
NTLLKNELFGEMLSKDTVGSESSIDRIKNTRPSTRGNVHAENTTRHGYELERVSTPPP
EAAGLEEFSPHSTPVTPRRLFTSQQDEITRPSSNSVRGASLLTYQQRKGRRLSAASLL
QSQFFDSMSPVRPDSKQLLLSPGKQFRQIAKVPYRVLDAPSLADDFYYSLIDWSSTDV
LAVALGKSIFLTDNNTGDVVHLCDTENEYTSLSWIGAGSHLAVGQANGLVEIYDVMKR
KCIRTLSGHIDRVACLSWNNHVLTSGSRDHRILHRDVRMPDPFFETIESHTQEVCGLK
WNVADNKLASGGNDNVVHVYEGTSKSPILTFDEHKAAVKAMAWSPHKRGVLATGGGTA
DRRLKIWNVNTSIKMSDIDSGSQICNMVWSKNTNELVTSHGYSKYNLTLWDCNSMDPI
AILKGHSFRVLHLTLSNDGTTVVSGAGDETLRYWKLFDKPKAKVQPNSLIFDAFNQIR
"
gene 494517..495167
/gene="ERP6"
/locus_tag="YGL002W"
/db_xref="GeneID:852882"
mRNA 494517..495167
/gene="ERP6"
/locus_tag="YGL002W"
/product="Erp6p"
/transcript_id="NM_001180867.1"
/db_xref="GI:296145037"
/db_xref="GeneID:852882"
CDS 494517..495167
/gene="ERP6"
/locus_tag="YGL002W"
/note="Member of the p24 family involved in ER to Golgi
transport; similar to Emp24p and Erv25p; the authentic,
non-tagged protein is detected in highly purified
mitochondria in high-throughput studies; ERP6 has a
paralog, ERP1, that arose from the whole genome
duplication"
/codon_start=1
/product="Erp6p"
/protein_id="NP_011513.1"
/db_xref="GI:6321436"
/db_xref="SGD:S000002970"
/db_xref="GeneID:852882"
/translation="MLSHYIFLAFVLLPFRVSAFYFYGYGGDRKCFLKELSKDTLLKG
SYNLEVYDDKLADYALPSYNDYGIVIDVEEVFDNNHRVVHQQGSPSGDFSFLALESGE
YKICLQSRVNNWVGKTKTKLEIEFEVGFEAMLDMQRKETLESLHGKVSILNSKIVDIR
REQQLMREREESFRDISESVNSRAMWWTVTQVTLLIIICVWQMKSLRSFFVKQKVL"
gene complement(495453..496502)
/gene="ERG26"
/locus_tag="YGL001C"
/db_xref="GeneID:852883"
mRNA complement(495453..496502)
/gene="ERG26"
/locus_tag="YGL001C"
/product="sterol-4-alpha-carboxylate 3-dehydrogenase
(decarboxylating)"
/transcript_id="NM_001180866.1"
/db_xref="GI:296145038"
/db_xref="GeneID:852883"
CDS complement(495453..496502)
/gene="ERG26"
/locus_tag="YGL001C"
/EC_number="1.1.1.170"
/note="C-3 sterol dehydrogenase, catalyzes the second of
three steps required to remove two C-4 methyl groups from
an intermediate in ergosterol biosynthesis"
/codon_start=1
/product="sterol-4-alpha-carboxylate 3-dehydrogenase
(decarboxylating)"
/protein_id="NP_011514.1"
/db_xref="GI:6321437"
/db_xref="SGD:S000002969"
/db_xref="GeneID:852883"
/translation="MSKIDSVLIIGGSGFLGLHLIQQFFDINPKPDIHIFDVRDLPEK
LSKQFTFNVDDIKFHKGDLTSPDDMENAINESKANVVVHCASPMHGQNPDIYDIVNVK
GTRNVIDMCKKCGVNILVYTSSAGVIFNGQDVHNADETWPIPEVPMDAYNETKAIAED
MVLKANDPSSDFYTVALRPAGIFGPGDRQLVPGLRQVAKLGQSKFQIGDNNNLFDWTY
AGNVADAHVLAAQKLLDPKTRTAVSGETFFITNDTPTYFWALARTVWKADGHIDKHVI
VLKRPVAICAGYLSEWVSKMLGKEPGLTPFRVKIVCAYRYHNIAKAKKLLGYTPRVGI
EEGINKTLAWMDEGL"
centromere complement(496920..497038)
/note="CEN7; Chromosome VII centromere"
/db_xref="SGD:S000006468"
centromere complement(496920..496944)
/note="CEN7_CDEIII of CEN7"
centromere complement(496945..497028)
/note="CEN7_CDEII of CEN7"
centromere complement(497029..497038)
/note="CEN7_CDEI of CEN7"
gene complement(497133..498034)
/locus_tag="YGR001C"
/db_xref="GeneID:852884"
mRNA complement(join(497133..497365,497459..497937,
498000..498034))
/locus_tag="YGR001C"
/product="hypothetical protein"
/transcript_id="NM_001181130.3"
/db_xref="GI:398365016"
/db_xref="GeneID:852884"
CDS complement(join(497133..497365,497459..497937,
498000..498034))
/locus_tag="YGR001C"
/note="hypothetical protein with similarity to
methyltransferase family members; green fluorescent
protein (GFP)-fusion protein localizes to the cytoplasm;
required for replication of Brome mosaic virus in S.
cerevisiae"
/codon_start=1
/product="hypothetical protein"
/protein_id="NP_011515.4"
/db_xref="GI:398365017"
/db_xref="SGD:S000003233"
/db_xref="GeneID:852884"
/translation="MSDSDSDSDYELTLSANALAALEEFKREEQQHQEAFQKLYDETD
EDFQKKKKEEGMKLFKEDWQLSQFWYSDDTAAILADAILEGADENTVIAIVSAPSVYA
AIQKKPTNEIPTEHIYLFEFDKRFELLAGRDHFFFYDYNKPLDFSDEIKGKVDRLLID
PPFLNEDCQTKSSITAKCLLAPNDNSKTKKGVFKHRLISCTGERMSEVISKVYSDTRI
TTFLPEHSNGLSNEFRCYANFECSSWKFAS"
gene complement(498476..499906)
/gene="SWC4"
/locus_tag="YGR002C"
/gene_synonym="EAF2; GOD1"
/db_xref="GeneID:852885"
mRNA complement(498476..499906)
/gene="SWC4"
/locus_tag="YGR002C"
/gene_synonym="EAF2; GOD1"
/product="Swc4p"
/transcript_id="NM_001181131.1"
/db_xref="GI:296145040"
/db_xref="GeneID:852885"
CDS complement(498476..499906)
/gene="SWC4"
/locus_tag="YGR002C"
/gene_synonym="EAF2; GOD1"
/note="Component of the Swr1p complex that incorporates
Htz1p into chromatin; component of the NuA4 histone
acetyltransferase complex"
/codon_start=1
/product="Swc4p"
/protein_id="NP_011516.1"
/db_xref="GI:6321439"
/db_xref="SGD:S000003234"
/db_xref="GeneID:852885"
/translation="MSSSDIFDVLNIKQKSRSPTNGQVSVPSSSAANRPKPQVTGMQR
ELFNLLGENQPPVVIKSGNNFKEKMLSTSKPSPWSFVEFKANNSVTLRHWVKGSKELI
GDTPKESPYSKFNQHLSIPSFTKEEYEAFMNENEGTQKSVESEKNHNENFTNEKKDES
KNSWSFEEIEYLFNLCKKYDLRWFLIFDRYSYNNSRTLEDLKEKFYYTCRNYFKASDP
SNPLLSSLNFSAEKEIERKKYLQRLLSRSAAEIAEEEALVVESKKFEMAAKRTLAERE
SLLRLLDSPHSDQTITQYLTSQGMSQLYNALLADKTRKRKHDLNIPENPWMKQQQQFA
QHRQLQQLNVKKSEVKENLSPKKTKRQRQEMQTALKRKSESAYAEQLLKDFNSDERKA
LGVITHGEKLSPGVYLRSTKLSTFKPALQNKILAILQELSLPSRPVMPSFDVMERQEE
LLKKINTLIDLKKHVDKYEAGMSITK"
gene 500132..502366
/gene="CUL3"
/locus_tag="YGR003W"
/db_xref="GeneID:852886"
mRNA 500132..502366
/gene="CUL3"
/locus_tag="YGR003W"
/product="Cul3p"
/transcript_id="NM_001181132.1"
/db_xref="GI:296145041"
/db_xref="GeneID:852886"
CDS 500132..502366
/gene="CUL3"
/locus_tag="YGR003W"
/note="Ubiquitin-protein ligase, forms a complex with
Elc1p that polyubiquitylates monoubiquitylated RNA
polymerase II to trigger its proteolysis; cullin family
member with similarity to Cdc53p and human CUL3"
/codon_start=1
/product="cullin CUL3"
/protein_id="NP_011517.1"
/db_xref="GI:6321440"
/db_xref="SGD:S000003235"
/db_xref="GeneID:852886"
/translation="MITNKKIKISVPEKLGLSEESFEESWETVKYAIDHIYSDDMADL
SFEQVYKTIYTIVLNKKGPILYNRLKDYLIQKLALLRETIVKDNTHDYEFLGTMARLW
EVQCHCFKITGDLMMYMDKVYCKPNRCMEVYDMCLDLFRIEILQKCSSSLISALISDI
ERIRNLGSVDSEHTSLWKVLIGMMETLHDNRDSFFLTDFEPVLISATEEYYNKAIDIE
LLTPIESLEKIRKLRQFESMLDSSFLNVDSHNKLKTVLENVLIWGKLSDIIEDLTHEA
MVISNGKLLQEIYDLSSEEKYRVTVIESIKSYINKNAINIPFNEGNRKKGQNAITWSS
EIVELYRSQHSFLESIDFGSVRLNNLTGDVSNAILGDVFSMYFSKEGALPSEYLSTYV
DHCMKRTKEKDAEIVKIKQDLLDSTKLIGLLTEKDIFEKIYKKQLSRRLLQQRSLVEI
EKWMVQMIKKVLGTFFTSKLEIMLRDISLSSEMYQAFQHSTINSIEYLSFAPQVLTRT
SWPFQSTNPIDEGISLPPRMSQILAGFEGYYSLKYKERVLKWAHHLSVIEIGCQFNSG
YYEISFSVYAGVIFLLFEDYEELTLGEIYELTHIPIDDVKSLVMSMSTIPRCKILKKS
SSSGNMKFSVNYFFSSPNRKVKVPVIACPLPSQKSDNLATASSVDTYDNEIVMELSAI
IVRIMKTEGKLSHQQLLERTTKRTQSRLSLTPSILKRSIQLLIEKEYIQRNADDPSYY
HYLS"
gene 502938..504326
/gene="PEX31"
/locus_tag="YGR004W"
/db_xref="GeneID:852887"
mRNA 502938..504326
/gene="PEX31"
/locus_tag="YGR004W"
/product="Pex31p"
/transcript_id="NM_001181133.1"
/db_xref="GI:296145042"
/db_xref="GeneID:852887"
CDS 502938..504326
/gene="PEX31"
/locus_tag="YGR004W"
/note="Peroxisomal integral membrane protein, involved in
negative regulation of peroxisome size; partially
functionally redundant with Pex30p and Pex32p; probably
acts at a step downstream of steps mediated by Pex28p and
Pex29p"
/codon_start=1
/product="Pex31p"
/protein_id="NP_011518.1"
/db_xref="GI:6321441"
/db_xref="SGD:S000003236"
/db_xref="GeneID:852887"
/translation="MSEINNENLEPTSSTVAESTESKNKHIRSALRKRRGKLSAQTYE
EDQEAILSSPLLTSTPKTVSRSLVRLYPYLIVVDNFLSIITWSNDNVSANLLGIFLFT
VCVLYFGFITRYFGHLMIVGIIWVYLLIDKHVQETMASCPSLDDIIHVMDRVSMKSSA
VLSPITILSAQDVRRLLFTIAFLSPVYIFLTVFVLSPNYLMLIGGLYVLTYHSKLIRR
MRRYLWKFRVVRLLVFFITGLDLGGPDNNRRLFASVNKKIRSFVWNEVGNTSNTKKTV
LFKVALFENQRRWLGIGWTSTMLSYERASWTDEFLNTSPSPEVFTLPEEQSGMAWEWH
DKDWMLDLTNDGIIQLPASAAKTKVKPGADEGFIYYDNTWNNPSATDTYKKYTRRRRW
IRTATVTTTYDDEPTVEKATPNSHALKSEENNRVRKRKVSFSTANEVHIIPSSDSSKL
IQISDVSMSPSL"
gene complement(504657..505859)
/gene="TFG2"
/locus_tag="YGR005C"
/db_xref="GeneID:852888"
mRNA complement(504657..505859)
/gene="TFG2"
/locus_tag="YGR005C"
/product="Tfg2p"
/transcript_id="NM_001181134.3"
/db_xref="GI:398365042"
/db_xref="GeneID:852888"
CDS complement(504657..505859)
/gene="TFG2"
/locus_tag="YGR005C"
/EC_number="3.6.1.-"
/note="TFIIF (Transcription Factor II) middle subunit;
involved in both transcription initiation and elongation
of RNA polymerase II; homologous to human RAP30"
/codon_start=1
/product="Tfg2p"
/protein_id="NP_011519.3"
/db_xref="GI:398365043"
/db_xref="SGD:S000003237"
/db_xref="GeneID:852888"
/translation="MSSGSAGAPALSNNSTNSVAKEKSGNISGDEYLSQEEEVFDGND
IENNETKVYEESLDLDLERSNRQVWLVRLPMFLAEKWRDRNNLHGQELGKIRINKDGS
KITLLLNENDNDSIPHEYDLELTKKVVENEYVFTEQNLKKYQQRKKELEADPEKQRQA
YLKKQEREEELKKKQQQQKRRNNRKKFNHRVMTDRDGRDRYIPYVKTIPKKTAIVGTV
CHECQVMPSMNDPNYHKIVEQRRNIVKLNNKERITTLDETVGVTMSHTGMSMRSDNSN
FLKVGREKAKSNIKSIRMPKKEILDYLFKLFDEYDYWSLKGLKERTRQPEAHLKECLD
KVATLVKKGPYAFKYTLRPEYKKLKEEERKATLGELADEQTGSAGDNAQGDAEADLED
EIEMEDVV"
gene 506070..506825
/gene="PRP18"
/locus_tag="YGR006W"
/db_xref="GeneID:852889"
mRNA 506070..506825
/gene="PRP18"
/locus_tag="YGR006W"
/product="Prp18p"
/transcript_id="NM_001181135.1"
/db_xref="GI:296145044"
/db_xref="GeneID:852889"
CDS 506070..506825
/gene="PRP18"
/locus_tag="YGR006W"
/note="Splicing factor involved in the positioning of the
3' splice site during the second catalytic step of
splicing, part of snRNP U5, interacts with Slu7p"
/codon_start=1
/product="Prp18p"
/protein_id="NP_011520.2"
/db_xref="GI:41629693"
/db_xref="SGD:S000003238"
/db_xref="GeneID:852889"
/translation="MDLDLASILKGEISKKKKELANSKGVQPPCTEKFQPHESANIDE
TPRQVEQESTDEENLSDNQSDDIRTTISKLENRPERIQEAIAQDKTISVIIDPSQIGS
TEGKPLLSMKCNLYIHEILSRWKASLEAYHPELFLDTKKALFPLLLQLRRNQLAPDLL
ISLATVLYHLQQPKEINLAVQSYMKLSIGNVAWPIGVTSVGIHARSAHSKIQGGRNAA
NIMIDERTRLWITSIKRLITFEEWYTSNHDSLA"
gene 506969..507940
/gene="ECT1"
/locus_tag="YGR007W"
/gene_synonym="MUQ1"
/db_xref="GeneID:852890"
mRNA 506969..507940
/gene="ECT1"
/locus_tag="YGR007W"
/gene_synonym="MUQ1"
/product="ethanolamine-phosphate cytidylyltransferase"
/transcript_id="NM_001181136.1"
/db_xref="GI:296145045"
/db_xref="GeneID:852890"
CDS 506969..507940
/gene="ECT1"
/locus_tag="YGR007W"
/gene_synonym="MUQ1"
/EC_number="2.7.7.14"
/note="Ethanolamine-phosphate cytidylyltransferase,
catalyzes the second step of phosphatidylethanolamine
biosynthesis; involved in the maintenance of plasma
membrane; similar to mammalian CTP: phosphocholine
cytidylyl-transferases"
/codon_start=1
/product="ethanolamine-phosphate cytidylyltransferase"
/protein_id="NP_011521.1"
/db_xref="GI:6321444"
/db_xref="SGD:S000003239"
/db_xref="GeneID:852890"
/translation="MTVNLDPDKVWIDGCFDFTHHGHAGAILQARRTVSKENGKLFCG
VHTDEDIQHNKGTPVMNSSERYEHTRSNRWCSEVVEAAPYVTDPNWMDKYQCQYVVHG
DDITIDANGEDCYKLVKEMGRFKVVKRTYGVSTTEIIHRILTKKSLPPTHPDYYPTTQ
ELSFYSVAQDAVSKHCYVFQRDLDNVLVNGGYKFDAEDCVYVDGDFDLFHMGDIDQLR
KLKMDLHPDKKLIVGITTSDYSSTIMTMKERVLSVLSCKYVDAVIIDADATSMSQYNC
EKYHIGTAVLTAAGKFSEYLTKELIVKRVESQREVYIARNQKKGMSI"
gene complement(508110..508364)
/gene="STF2"
/locus_tag="YGR008C"
/db_xref="GeneID:852891"
mRNA complement(508110..508364)
/gene="STF2"
/locus_tag="YGR008C"
/product="Stf2p"
/transcript_id="NM_001181137.1"
/db_xref="GI:296145046"
/db_xref="GeneID:852891"
CDS complement(508110..508364)
/gene="STF2"
/locus_tag="YGR008C"
/note="Protein involved in resistance to dessication
stress; Stf2p exhibits antioxidant properties, and its
overexpression prevents ROS accumulation and apoptosis;
binds to the F0 sector of mitochondrial F1F0 ATPase in
vitro and is proposed to modulate the inhibitory action of
Inh1p and Stf1p; protein abundance increases in response
to DNA replication stress"
/codon_start=1
/product="Stf2p"
/protein_id="NP_011522.1"
/db_xref="GI:6321445"
/db_xref="SGD:S000003240"
/db_xref="GeneID:852891"
/translation="MTRTNKWTEREGKADPKYFSHTGNYGESPNHIKKQGSGKGNWGK
PGDEIDDLIDNGEIPPVFKKDRRGSNLQSHEQKFENVQKE"
rep_origin 508729..508977
/note="ARS720;
Autonomously Replicating Sequence"
/db_xref="SGD:S000118460"
gene complement(509047..511002)
/gene="SEC9"
/locus_tag="YGR009C"
/gene_synonym="HSS7"
/db_xref="GeneID:852892"
mRNA complement(509047..511002)
/gene="SEC9"
/locus_tag="YGR009C"
/gene_synonym="HSS7"
/product="Sec9p"
/transcript_id="NM_001181138.3"
/db_xref="GI:398365078"
/db_xref="GeneID:852892"
CDS complement(509047..511002)
/gene="SEC9"
/locus_tag="YGR009C"
/gene_synonym="HSS7"
/note="t-SNARE protein important for fusion of secretory
vesicles with the plasma membrane; similar to but not
functionally redundant with Spo20p; SNAP-25 homolog"
/codon_start=1
/product="Sec9p"
/protein_id="NP_011523.3"
/db_xref="GI:398365079"
/db_xref="SGD:S000003241"
/db_xref="GeneID:852892"
/translation="MGLKKFFKIKPPEEATPEQNKDTLMELGISVKNPSKKRKEKFAA
YGKFANDKAEDKVYAPPGYEQYARPQDELEDLNASPLDANANEATAGSNRGSSGTQDL
GNGAESNSMQDPYAIENDDYRYDDDPYARFQANKSNGRGSVNAAPYGDYGGGYNGTSL
NSYNNDGPYSNQNTSNSWVNANGRNSLNHSNSTLNVGPSRQTRQPPVSTSTNSLSLDQ
RSPLANPMQEKRNPYADMNSYGGAYDSNTNRSSGTRQGSSKNANPYASMANDSYSNGN
LNRSANPYSSRSVRQPQSQQAPMTYTPSFIASDEAARNSEVDLNEEPRTGEFDFEEVY
ADKSAENRAALDEPDLNAVMTNEDSIDLNASEVDHSSRQQQQQQWFMDEQQQQQQHFN
ATNNQYGDQRGYKTFEEIQKEEEARQQQEEDEAVDEIKQEIKFTKQSSVASTRNTLKM
AQDAERAGMNTLGMLGHQSEQLNNVEGNLDLMKVQNKVADEKVAELKKLNRSILAVHV
SNPFNSKRRRREREEQLKNRKIEEKLMREQTSQQLSQSTQRIEGAMNANNNISEVRER
YQRKNVLEKAKRYQFENDEEDDEMELEIDRNLDQIQQVSNRLKKMALTTGKELDSQQK
RLNNIEESTDDLDINLHMNTNRLAGIR"
gene 511545..512732
/gene="NMA2"
/locus_tag="YGR010W"
/db_xref="GeneID:852893"
mRNA 511545..512732
/gene="NMA2"
/locus_tag="YGR010W"
/product="nicotinamide-nucleotide adenylyltransferase
NMA2"
/transcript_id="NM_001181139.1"
/db_xref="GI:296145048"
/db_xref="GeneID:852893"
CDS 511545..512732
/gene="NMA2"
/locus_tag="YGR010W"
/EC_number="2.7.7.18"
/EC_number="2.7.7.1"
/note="Nicotinic acid mononucleotide adenylyltransferase;
catalyzes the transfer of the adenylyl moiety of ATP to
nicotinamide mononucleotide to form NAD; involved in de
novo and salvage synthesis of NAD(+); NMA2 has a paralog,
NMA1, that arose from the whole genome duplication"
/codon_start=1
/product="nicotinamide-nucleotide adenylyltransferase
NMA2"
/protein_id="NP_011524.1"
/db_xref="GI:6321447"
/db_xref="SGD:S000003242"
/db_xref="GeneID:852893"
/translation="MDPTKAPDFKPPQPNEELQPPPDPTHTIPKSGPIVPYVLADYNS
SIDAPFNLDIYKTLSSRKKNANSSNRMDHIPLNTSDFQPLSRDVSSEEESEGQSNGID
ATLQDVTMTGNLGVLKSQIADLEEVPHTIVRQARTIEDYEFPVHRLTKKLQDPEKLPL
IIVACGSFSPITYLHLRMFEMALDDINEQTRFEVVGGYFSPVSDNYQKRGLAPAYHRV
RMCELACERTSSWLMVDAWESLQSSYTRTAKVLDHFNHEINIKRGGIMTVDGEKMGVK
IMLLAGGDLIESMGEPHVWADSDLHHILGNYGCLIVERTGSDVRSFLLSHDIMYEHRR
NILIIKQLIYNDISSTKVRLFIRRGMSVQYLLPNSVIRYIQEYNLYINQSEPVKQVLD
SKE"
gene 513159..514340
/locus_tag="YGR012W"
/db_xref="GeneID:852895"
mRNA 513159..514340
/locus_tag="YGR012W"
/product="putative cysteine synthase"
/transcript_id="NM_001181141.1"
/db_xref="GI:296145049"
/db_xref="GeneID:852895"
CDS 513159..514340
/locus_tag="YGR012W"
/EC_number="2.5.1.47"
/note="Putative cysteine synthase, localized to the
mitochondrial outer membrane"
/codon_start=1
/product="putative cysteine synthase"
/protein_id="NP_011526.1"
/db_xref="GI:6321449"
/db_xref="SGD:S000003244"
/db_xref="GeneID:852895"
/translation="MSCSQNKTSVSLAWRECISIASVLIGAYASYKYYKLFKTRDIPR
PKEGVEELIGNTPLVKIRSLTKATGVNIYAKLELCNPAGSAKDRVALNIIKTAEELGE
LVRGEPGWVFEGTSGSTGISIAVVCNALGYRAHISLPDDTSLEKLALLESLGATVNKV
KPASIVDPNQYVNAAKKACNELKKSGNGIRAVFADQFENEANWKVHYQTTGPEIAHQT
KGNIDAFIAGCGTGGTITGVAKFLKERAKIPCHVVLADPQGSGFYNRVNYGVMYDYVE
KEGTRRRHQVDTIVEGIGLNRITHNFHMGEKFIDESIRVNDNQAIRMAKYLSVNDGLF
VGSSTAINAVAAIQVAKTLPHGSNIVIIACDSGSRHLSKFWKEAKEIDHDVSLEEVIN
I"
gene 514554..516416
/gene="SNU71"
/locus_tag="YGR013W"
/db_xref="GeneID:852896"
mRNA 514554..516416
/gene="SNU71"
/locus_tag="YGR013W"
/product="Snu71p"
/transcript_id="NM_001181142.1"
/db_xref="GI:296145050"
/db_xref="GeneID:852896"
CDS 514554..516416
/gene="SNU71"
/locus_tag="YGR013W"
/note="Component of U1 snRNP required for mRNA splicing
via spliceosome; yeast specific, no metazoan counterpart"
/codon_start=1
/product="Snu71p"
/protein_id="NP_011527.1"
/db_xref="GI:6321450"
/db_xref="SGD:S000003245"
/db_xref="GeneID:852896"
/translation="MRDIVFVSPQLYLSSQEGWKSDSAKSGFIPILKNDLQRFQDSLK
HIVDARNSLSETLLNSNDDGSIHNSDQNTGLNKDKEASIADNNSANKCATSSSRYQEL
KQFLPISLDQQIHTVSLQGVSSSFSRGQIESLLDHCLNLALTETQSNSALKVEAWSSF
SSFLDTQDIFIRFSKVDEDEAFVNTLNYCKALFAFIRKLHEDFKIELHLDLNTKEYVE
DRTGTIPSVKPEKASEFYSVFKNIEDQTDERNSKKEQLDDSSTQYKVDTNTLSDLPSD
ALDQLCKDIIEFRTKVVSIEKEKKMKSTYEESRRQRHQMQKVFDQIRKNHSGAKGSAN
TEEEDTNMEDEDEEDDTEDDLALEKRKEERDLEESNRRYEDMLHQLHSNTEPKIKSIR
ADIMSAENYEEHLEKNRSLYLKELLHLANDVHYDHHRSFKEQEERRDEEDRAKNGNAK
ELAPIQLSDGKAISAGKAAAITLPEGTVKSENYNADKNVSESSEHVKIKFDFKKAIDH
SVESSSEDEGYRESELPPTKPSERSAAEDRLPFTADELNIRLTNLKESRYVDELVREF
LGVYEDELVEYILENIRVNQSKQALLNELRETFDEDGETIADRLWSRKEFRLGT"
gene 516943..520863
/gene="MSB2"
/locus_tag="YGR014W"
/db_xref="GeneID:852897"
mRNA 516943..520863
/gene="MSB2"
/locus_tag="YGR014W"
/product="Msb2p"
/transcript_id="NM_001181143.3"
/db_xref="GI:398365106"
/db_xref="GeneID:852897"
CDS 516943..520863
/gene="MSB2"
/locus_tag="YGR014W"
/note="Mucin family member involved in signaling;
functions in the Cdc42p- and MAP kinase-dependent
filamentous growth signaling pathway; is processed into
secreted and cell-associated forms by the aspartyl
protease, Yps1p; also functions as an osmosensor in
parallel to the Sho1p-mediated pathway; potential Cdc28p
substrate"
/codon_start=1
/product="Msb2p"
/protein_id="NP_011528.3"
/db_xref="GI:398365107"
/db_xref="SGD:S000003246"
/db_xref="GeneID:852897"
/translation="MQFPFACLLSTLVISGSLARASPFDFIFGNGTQQAQSQSESQGQ
VSFTNEASQDSSTTSLVTAYSQGVHSHQSATIVSATISSLPSTWYDASSTSQTSVSYA
SQESDYAVNQNSWSASTNQLPSTSTTSYYAPTFSTSADFAASSVNAASDVSTASVPID
TSANSIPFTTTSNIETTTSAPLTSDTPLISTSTMSAADNVFSSANPISASLTTTDSSE
SFDQTSTAGAIPVQSSADFSSSSEILVQSSADFSSPSSPTTTDISLSAAPLQTSESSS
FTTASAALPVSSTDVDGSSASPVVSMSAAGQIASSSSTDNPTMSETFSLTSTEVDGSD
VSSTVSALLSAPFLQTSTSNSFSIVSPSVSFVPSQSSSDVASSSTANVVSSSFSDIPP
QTSTSGSVVSVAQSASALAFQSSTEVYGASASSTMSSLLSTTSLQSTTLDSSSLASSS
ASSSDLTDYGVSSTASIPLLSASEQASTSSSFSVVSPSVSFVPSQSSSDVASTSAPSV
VSSSFSYTSLQAGGSSMTNPSSSTIVYSSSTGSSEESAASTASATLSGSSSTYMAGNL
QSQPPSTSSLLSESQATSTSAVLASSSVSTTSPYTTAGGASTEASSLISSTSAETSQV
SYSQSTTALQTSSFASSSTTEGSETSSQGFSTSSVLVQMPSSISSEFSPSQTTTQMNS
ASSSSQYTISSTGILSQVSDTSVSYTTSSSSVSQVSDTPVSYTTSSSSVSQVSDTPVS
YTTSSSSVSQVSDTPVSYTTSSSSVSQVSDTPVSYTTSSSSVSQVSDTSVPSTSSRSS
VSQVSDTPVPSTSSRSSVSQTSSSLQPTTTSSQRFTISTHGALSESSSVSQQASEITS
SINATASEYHSIQTTAATQSTTLSFTDANSSSASAPLEVATSTPTPSSKASSLLLTPS
TSSLSQVATNTNVQTSLTTESTTVLEPSTTNSSSTFSLVTSSDNNWWIPTELITQAPE
AASTASSTVGGTQTMTLPHAIAAATQVPEPEGYTLITIGFKKALNYEFVVSEPKSSAQ
IFGYLPEALNTPFKNVFTNITVLQIVPLQDDSLNYLVSVAEVYFPTAEIEELSNLITN
SSSAFYTDGMGTAKSMAAMVDSSIPLTGLLHDSNSNSGGSSDGSSSSNSNSGSSGSGS
NSNSGVSSSSGNSYQDAGTLEYSSKSNSNVSTSSKSKKKIIGLVIGVVVGGCLYILFM
IFAFKYIIRRRIQSQEIIKNPEISSISSSEFGGEKNYNNEKRMSVQESITQSMRIQNW
MDDSYYGHGLTNNDSTPTRHNTSSSIPKISRPIASQNSLGWNEV"
gene complement(521090..522076)
/locus_tag="YGR015C"
/db_xref="GeneID:852898"
mRNA complement(521090..522076)
/locus_tag="YGR015C"
/product="hypothetical protein"
/transcript_id="NM_001181144.1"
/db_xref="GI:296145052"
/db_xref="GeneID:852898"
CDS complement(521090..522076)
/locus_tag="YGR015C"
/note="hypothetical protein; green fluorescent protein
(GFP)-fusion protein localizes to the mitochondrion"
/codon_start=1
/product="hypothetical protein"
/protein_id="NP_011529.1"
/db_xref="GI:6321452"
/db_xref="SGD:S000003247"
/db_xref="GeneID:852898"
/translation="MSRLAHNKALPYKIIVDLSFHRTRLPSDVSSLIKFEQRPAIINI
HGLLGSHVMFHSLNKLLSRKLDADIFSVDVRNHGISPKAIPYDYTTLTNDLIYFIETH
IGLERPIYLLGFSMGGKIALLTTLYKNINIRKCISIDLPPYETPELDPMILQNYDLIM
RIIRRDVKILRGSPSWQKKVLELFKSLECNKRKCGGAVALYFANGFLSVKSNNVHQAQ
LHYEQQQHDPYINYSMPLSSMPNLLDEVKKWPDLSNQRDFFQKGTASRKVLFMKGLQS
NFINNDYSLLRYNFPCADVREFNTGHNLLLENPEDSFKCILNFFAEETLDFE"
gene 522261..522833
/locus_tag="YGR016W"
/db_xref="GeneID:852899"
mRNA 522261..522833
/locus_tag="YGR016W"
/product="hypothetical protein"
/transcript_id="NM_001181145.1"
/db_xref="GI:296145053"
/db_xref="GeneID:852899"
CDS 522261..522833
/locus_tag="YGR016W"
/codon_start=1
/product="hypothetical protein"
/protein_id="NP_011530.1"
/db_xref="GI:6321453"
/db_xref="SGD:S000003248"
/db_xref="GeneID:852899"
/translation="MSRLRRFNRKILSLSSDYTHDGESDQEDVSILPLDTEEQEELIQ
KFETNAHITNKLYINLLSILYLLYGGLLMILVRKSRGYIKLALLAGANSLICSCITLR
YDIVNDYLLFKKFKLRVSNFSINIINIILLVLMAWISFNHVVEDKKTVLCLQVPMFLF
WVAVLVKRWARNIEDEIADLRCLKYKYKNA"
gene 523787..524680
/locus_tag="YGR017W"
/db_xref="GeneID:852900"
mRNA 523787..524680
/locus_tag="YGR017W"
/product="hypothetical protein"
/transcript_id="NM_001181146.1"
/db_xref="GI:296145054"
/db_xref="GeneID:852900"
CDS 523787..524680
/locus_tag="YGR017W"
/note="hypothetical protein; green fluorescent protein
(GFP)-fusion protein localizes to both the nucleus and the
cytoplasm"
/codon_start=1
/product="hypothetical protein"
/protein_id="NP_011531.1"
/db_xref="GI:6321454"
/db_xref="SGD:S000003249"
/db_xref="GeneID:852900"
/translation="MSHQMAPWIPMFIQSCKNNTEPFVSFQFATVDELTNKPRCRTVV
FRDFLFHDKRTNVLTFNTDMRSSKITESFITPNSNNSSDSKRCETPFFEACFYFPETW
EQYRFSGQCFTISKQFKKIPAEIVTKYDIFSPRFSETNDDSTDEEIDTPINDDDDDDK
NNDADNNDINEDNKLIESIENDEHHEDEDDYYPQPQEWEAELLRQWSSLSRHTKSLYR
KPAPGQKLTSETSKQLDKLHRGVDGAKEDAGLENFGIVCLCVDSVDFLNLKEGRGGER
WIFQKTDGKDEDLWEEQEVCP"
gene complement(524365..524694)
/locus_tag="YGR018C"
/db_xref="GeneID:852901"
mRNA complement(524365..524694)
/locus_tag="YGR018C"
/product="hypothetical protein"
/transcript_id="NM_001270747.1"
/db_xref="GI:398365132"
/db_xref="GeneID:852901"
CDS complement(524365..524694)
/locus_tag="YGR018C"
/note="hypothetical protein; mRNA identified as translated
by ribosome profiling data; partially overlaps the
uncharacterized ORF YGR017W"
/codon_start=1
/product="hypothetical protein"
/protein_id="NP_001257676.1"
/db_xref="GI:398365133"
/db_xref="SGD:S000003250"
/db_xref="GeneID:852901"
/translation="MIDISHGHTSCSSHRSSSLPSVFWKIHLSPPLPSFKFKKSTEST
QRQTIPKFSSPASSLAPSTPLWSLSSCLLVSEVSFWPGAGFLYNDLVCLDREDHCLSN
SASHSCG"
gene 525229..526644
/gene="UGA1"
/locus_tag="YGR019W"
/db_xref="GeneID:852902"
mRNA 525229..526644
/gene="UGA1"
/locus_tag="YGR019W"
/product="4-aminobutyrate transaminase"
/transcript_id="NM_001181148.3"
/db_xref="GI:398365138"
/db_xref="GeneID:852902"
CDS 525229..526644
/gene="UGA1"
/locus_tag="YGR019W"
/EC_number="2.6.1.19"
/note="Gamma-aminobutyrate (GABA) transaminase; also known
as 4-aminobutyrate aminotransferase; involved in the
4-aminobutyrate and glutamate degradation pathways;
required for normal oxidative stress tolerance and
nitrogen utilization; protein abundance increases in
response to DNA replication stress"
/codon_start=1
/product="4-aminobutyrate transaminase"
/protein_id="NP_011533.3"
/db_xref="GI:398365139"
/db_xref="SGD:S000003251"
/db_xref="GeneID:852902"
/translation="MSICEQYYPEEPTKPTVKTESIPGPESQKQLKELGEVFDTRPAY
FLADYEKSLGNYITDVDGNTYLDLYAQISSIALGYNNPALIKAAQSPEMIRALVDRPA
LGNFPSKDLDKILKQILKSAPKGQDHVWSGLSGADANELAFKAAFIYYRAKQRGYDAD
FSEKENLSVMDNDAPGAPHLAVLSFKRAFHGRLFASGSTTCSKPIHKLDFPAFHWPHA
EYPSYQYPLDENSDANRKEDDHCLAIVEELIKTWSIPVAALIIEPIQSEGGDNHASKY
FLQKLRDITLKYNVVYIIDEVQTGVGATGKLWCHEYADIQPPVDLVTFSKKFQSAGYF
FHDPKFIPNKPYRQFNTWCGEPARMIIAGAIGQEISDKKLTEQCSRVGDYLFKKLEGL
QKKYPENFQNLRGKGRGTFIAWDLPTGEKRDLLLKKLKLNGCNVGGCAVHAVRLRPSL
TFEEKHADIFIEALAKSVNEL"
gene complement(526973..527329)
/gene="VMA7"
/locus_tag="YGR020C"
/db_xref="GeneID:852903"
mRNA complement(526973..527329)
/gene="VMA7"
/locus_tag="YGR020C"
/product="Vma7p"
/transcript_id="NM_001181149.1"
/db_xref="GI:296145056"
/db_xref="GeneID:852903"
CDS complement(526973..527329)
/gene="VMA7"
/locus_tag="YGR020C"
/EC_number="3.6.3.14"
/note="Subunit F of the eight-subunit V1 peripheral
membrane domain of vacuolar H+-ATPase (V-ATPase), an
electrogenic proton pump found throughout the endomembrane
system; required for the V1 domain to assemble onto the
vacuolar membrane"
/codon_start=1
/product="Vma7p"
/protein_id="NP_011534.1"
/db_xref="GI:6321457"
/db_xref="SGD:S000003252"
/db_xref="GeneID:852903"
/translation="MAEKRTLIAVIADEDTTTGLLLAGIGQITPETQEKNFFVYQEGK
TTKEEITDKFNHFTEERDDIAILLINQHIAENIRARVDSFTNAFPAILEIPSKDHPYD
PEKDSVLKRVRKLFGE"
gene 527632..528504
/locus_tag="YGR021W"
/db_xref="GeneID:852904"
mRNA 527632..528504
/locus_tag="YGR021W"
/product="hypothetical protein"
/transcript_id="NM_001181150.1"
/db_xref="GI:296145057"
/db_xref="GeneID:852904"
CDS 527632..528504
/locus_tag="YGR021W"
/note="hypothetical protein; the authentic, non-tagged
protein is detected in highly purified mitochondria in
high-throughput studies"
/codon_start=1
/product="hypothetical protein"
/protein_id="NP_011535.1"
/db_xref="GI:6321458"
/db_xref="SGD:S000003253"
/db_xref="GeneID:852904"
/translation="MLVRNRYLGELLKNSRSFSVLNSSVRSGHNKWSTIKHGKAKNDA
ERNKINNKFANQIAMSVKLGNGITDPSMNIRLATSIELANKNNVSKKVIENAIRKASG
SSASGKDSNASELCVYEGMGPGGVAIVVEALTDNKNRTIGLIRSAFNKANGSMTPTLF
FFDKKGYVTMVPPKMLDTEDKVLESVLEIQGIEDIAPVQEDAEDLECDTETETTGQTY
EAVMEPADTNKVAALLKERGFHIRDLGIGYNAKPDMEVFVQGDETLEKLQKLTTALED
IDEVTSLYTNASNA"
gene 529264..530919
/gene="MTL1"
/locus_tag="YGR023W"
/db_xref="GeneID:852905"
mRNA 529264..530919
/gene="MTL1"
/locus_tag="YGR023W"
/product="Mtl1p"
/transcript_id="NM_001181152.1"
/db_xref="GI:296145058"
/db_xref="GeneID:852905"
CDS 529264..530919
/gene="MTL1"
/locus_tag="YGR023W"
/note="Putative plasma membrane sensor, involved in cell
integrity signaling and stress response during glucose
starvation and oxidative stress; has structural and
functional similarity to Mid2p"
/codon_start=1
/product="Mtl1p"
/protein_id="NP_011537.1"
/db_xref="GI:6321459"
/db_xref="SGD:S000003255"
/db_xref="GeneID:852905"
/translation="MASCNPTRKKSSASSLSMWRTILMALTTLPLSVLSQELVPANST
TSSTAPSITSLSAVESFTSSTDATSSASLSTPSIASVSFTSFPQSSSLLTLSSTLSSE
LSSSSMQVSSSSTSSSSSEVTSSSSSSSISPSSSSSTIISSSSSLPTFTVASTSSTVA
SSTLSTSSSLVISTSSSTFTFSSESSSSLISSSISTSVSTSSVYVPSSSTSSPPSSSS
ELTSSSYSSSSSSSTLFSYSSSFSSSSSSSSSSSSSSSSSSSSSSSYFTLSTSSSSSI
YSSSSYPSFSSSSSSNPTSSITSTSASSSITPASEYSNLAKTITSIIEGQTILSNYYT
TITYSPTASASSGKNSHHSGLSKKNRNIIIGCVVGIGAPLILILLILIYMFCVQPKKT
DFIDSDGKIVTAYRSNIFTKIWYFLLGKKIGETERFSSDSPIGSNNIQNFGDIDPEDI
LNNDNPYTPKHTNVEGYDDDDDDDANDENLSSNFHNRGIDDQYSPTKSASYSMSNSNS
QDYNDADEVMHDENIHRVYDDSEASIDENYYTKPNNGLNITNY"
gene 531610..531681
/locus_tag="tD(GUC)G1"
/db_xref="GeneID:852907"
tRNA 531610..531681
/locus_tag="tD(GUC)G1"
/product="tRNA-Asp"
/note="Aspartate tRNA (tRNA-Asp), predicted by tRNAscan-SE
analysis"
/db_xref="SGD:S000006532"
/db_xref="GeneID:852907"
gene complement(531883..532596)
/gene="THG1"
/locus_tag="YGR024C"
/db_xref="GeneID:852908"
mRNA complement(531883..532596)
/gene="THG1"
/locus_tag="YGR024C"
/product="Thg1p"
/transcript_id="NM_001181153.3"
/db_xref="GI:398365170"
/db_xref="GeneID:852908"
CDS complement(531883..532596)
/gene="THG1"
/locus_tag="YGR024C"
/EC_number="2.7.7.-"
/note="tRNAHis guanylyltransferase, adds a guanosine
residue to the 5' end of tRNAHis after transcription and
RNase P cleavage; couples nuclear division and migration
to cell budding and cytokinesis; essential enzyme
conserved among eukaryotes"
/codon_start=1
/product="Thg1p"
/protein_id="NP_011538.3"
/db_xref="GI:398365171"
/db_xref="SGD:S000003256"
/db_xref="GeneID:852908"
/translation="MANSKFGYVRQFETHDVILPQCYIVVRIDGKKFHEFSKFYEFAK
PNDENALKLMNACAKNLVLKYKNDIILAFGESDEYSFILKSSTTLFNRRKDKLATLFG
SFFTSNYVALWAKFFPEKPLNIKHLPYFDSRCVAYPNLQTIKDYLSWRYVDTHINNLY
NTTFWQLIIKCGLTPQESEKKLCGTFSNEKQEILFSECGINYNNEPEMFKKGSLVTRK
GEILHINVIAQIDELFEGY"
gene 532985..533821
/locus_tag="YGR026W"
/db_xref="GeneID:852910"
mRNA 532985..533821
/locus_tag="YGR026W"
/product="hypothetical protein"
/transcript_id="NM_001181155.3"
/db_xref="GI:398365178"
/db_xref="GeneID:852910"
CDS 532985..533821
/locus_tag="YGR026W"
/note="hypothetical protein; green fluorescent protein
(GFP)-fusion protein localizes to the cell periphery"
/codon_start=1
/product="hypothetical protein"
/protein_id="NP_011540.3"
/db_xref="GI:398365179"
/db_xref="SGD:S000003258"
/db_xref="GeneID:852910"
/translation="MAKTIKVIRKKDPKKKNLSDPLAKQKLVWKIGHVLTLVFGLLFS
ITYFYHVLIFFKYRSWKWLFLRVNKNYSFIQSKRWYMKLLSWSPQVMYRLSLIGVFMS
ESVTMQQNWVGLNPTWNDLLSSENFHTLLIACLWFFGGGKSFYKILPYMILSYLHLTK
MNYELNANKEEKIPLTPKDRKMLHLLAYSELLVILALTLDTILFKTGTSGFMLVIYVG
IYWLRLNFSPYAQVAVLELLVKFEKYVPKKYRDKWQVIKNFIYMKMKEHEKRTEEVAR
YA"
gene complement(534132..534458)
/gene="RPS25A"
/locus_tag="YGR027C"
/gene_synonym="RPS31A"
/db_xref="GeneID:852911"
mRNA complement(534132..534458)
/gene="RPS25A"
/locus_tag="YGR027C"
/gene_synonym="RPS31A"
/product="ribosomal 40S subunit protein S25A"
/transcript_id="NM_001181156.1"
/db_xref="GI:296145061"
/db_xref="GeneID:852911"
CDS complement(534132..534458)
/gene="RPS25A"
/locus_tag="YGR027C"
/gene_synonym="RPS31A"
/note="Protein component of the small (40S) ribosomal
subunit; homologous to mammalian ribosomal protein S25, no
bacterial homolog; RPS25A has a paralog, RPS25B, that
arose from the whole genome duplication"
/codon_start=1
/product="ribosomal 40S subunit protein S25A"
/protein_id="NP_011541.1"
/db_xref="GI:6321464"
/db_xref="SGD:S000003259"
/db_xref="GeneID:852911"
/translation="MPPKQQLSKAAKAAAALAGGKKSKKKWSKKSMKDRAQHAVILDQ
EKYDRILKEVPTYRYVSVSVLVDRLKIGGSLARIALRHLEKEGIIKPISKHSKQAIYT
RATASE"
LTR 535211..535542
/note="Ty1 LTR"
/db_xref="SGD:S000006965"
LTR complement(535607..535759)
/note="Ty1 LTR"
/db_xref="SGD:S000006952"
mobile_element 535760..541685
/note="YGRWTy1-1; Ty1 element, LTR retrotransposon of the
Copia (Pseudoviridae) group; contains co-transcribed genes
TYA Gag and TYB Pol, encoding proteins involved in
structure and function of virus-like particles, flanked by
two direct repeats"
/mobile_element_type="retrotransposon:YGRWTy1-1"
/db_xref="SGD:S000006982"
LTR 535760..536097
/note="Ty1 LTR"
/db_xref="SGD:S000006966"
gene 536057..541325
/locus_tag="YGR027W-B"
/db_xref="GeneID:852913"
mRNA join(<536057..537361,537363..>541325)
/locus_tag="YGR027W-B"
/transcript_id="NM_001184432.1"
/db_xref="GI:296145063"
/db_xref="GeneID:852913"
CDS join(536057..537361,537363..541325)
/locus_tag="YGR027W-B"
/EC_number="2.7.7.49"
/EC_number="3.4.23.-"
/EC_number="3.1.26.4"
/EC_number="2.7.7.7"
/ribosomal_slippage
/note="Retrotransposon TYA Gag and TYB Pol genes;
transcribed/translated as one unit; polyprotein is
processed to make a nucleocapsid-like protein (Gag),
reverse transcriptase (RT), protease (PR), and integrase
(IN); similar to retroviral genes"
/codon_start=1
/product="gag-pol fusion protein"
/protein_id="NP_058158.1"
/db_xref="GI:7839171"
/db_xref="SGD:S000007406"
/db_xref="GeneID:852913"
/translation="MESQQLSQHSHISHGSACASVTSKEVHTNQDPLDVSASKTEECE
KASTKANSQQTTTPASSAVPENPHHASPQTAQSHSPQNGPYPQQCMMTQNQANPSGWS
FYGHPSMIPYTPYQMSPMYFPPGPQSQFPQYPSSVGTPLSTPSPESGNTFTDSSSADS
DMTSTKKYVRPPPMLTSPNDFPNWVKTYIKFLQNSNLGGIIPTVNGKPVRQITDDELT
FLYNTFQIFAPSQFLPTWVKDILSVDYTDIMKILSKSIEKMQSDTQEANDIVTLANLQ
YNGSTPADAFETKVTNIIDRLNNNGIHINNKVACQLIMRGLSGEYKFLRYTRHRHLNM
TVAELFLDIHAIYEEQQGSRNSKPNYRRNLSDEKNDSRSYTNTTKPKVIARNPQKTNN
SKSKTARAHNVSTSNNSPSTDNDSISKSTTEPIQLNNKHDLHLGQELTESTVNHTNHS
DDELPGHLLLDSGASRTLIRSAHHIHSASSNPDINVVDAQKRNIPINAIGDLQFHFQD
NTKTSIKVLHTPNIAYDLLSLNELAAVDITACFTKNVLERSDGTVLAPIVQYGDFYWV
SKRYLLPSNISVPTINNVHTSESTRKYPYPFIHRMLAHANAQTIRYSLKNNTITYFNE
SDVDWSSAIDYQCPDCLIGKSTKHRHIKGSRLKYQNSYEPFQYLHTDIFGPVHNLPKS
APSYFISFTDETTKFRWVYPLHDRREDSILDVFTTILAFIKNQFQASVLVIQMDRGSE
YTNRTLHKFLEKNGITPCYTTTADSRAHGVAERLNRTLLDDCRTQLQCSGLPNHLWFS
AIEFSTIVRNSLASPKSKKSARQHAGLAGLDISTLLPFGQPVIVNDHNPNSKIHPRGI
PGYALHPSRNSYGYIIYLPSLKKTVDTTNYVILQGKESRLDQFNYDALTFDEDLNRLT
ASYHSFIASNEIQESNDLNIESDHDFQSDIELHPEQPRNVLSKAVSPTDSTPPSTHTE
DSKRVSKTNIRAPREVDPNISESNILPSKKRSSTPQISNIESTGSGGMHKLNVPLLAP
MSQSNTHESSHASKSKDFRHSDSYSENETNHTNVPISSTGGTNNKTVPQISDQETEKR
IIHRSPSIDASPPENNSSHNIVPIKTPTTVSEQNTEESIIADLPLPDLPPESPTEFPD
PFKELPPINSRQTNSSLGGIGDSNAYTTINSKKRSLEDNETEIKVSRDTWNTKNMRSL
EPPRSKKRIHLIAAVKAVKSIKPIRTTLRYDEAITYNKDIKEKEKYIEAYHKEVNQLL
KMKTWDTDEYYDRKEIDPKRVINSMFIFNKKRDGTHKARFVARGDIQHPDTYDSGMQS
NTVHHYALMTSLSLALDNNYYITQLDISSAYLYADIKEELYIRPPPHLGMNDKLIRLK
KSLYGLKQSGANWYETIKSYLIQQCGMEEVRGWSCVFKNSQVTICLFVDDMVLFSKNL
NSNKRIIDKLKMQYDTKIINLGESDEEIQYDILGLEIKYQRGKYMKLGMENSLTEKIP
KLNVPLNPKGRKLSAPGQPGLYIDQQELELEEDDYKMKVHEMQKLIGLASYVGYKFRF
DLLYYINTLAQHILFPSKQVLDMTYELIQFIWNTRDKQLIWHKSKPVKPTNKLVVISD
ASYGNQPYYKSQIGNIYLLNGKVIGGKSTKASLTCTSTTEAEIHAISESVPLLNNLSY
LIQELDKKPITKGLLTDSKSTISIIISNNEEKFRNRFFGTKAMRLRDEVSGNHLHVCY
IETKKNIADVMTKPLPIKTFKLLTNKWIH"
gene 536057..537379
/locus_tag="YGR027W-A"
/db_xref="GeneID:852912"
mRNA <536057..>537379
/locus_tag="YGR027W-A"
/transcript_id="NM_001184431.1"
/db_xref="GI:296145062"
/db_xref="GeneID:852912"
CDS 536057..537379
/locus_tag="YGR027W-A"
/note="Retrotransposon TYA Gag gene co-transcribed with
TYB Pol; translated as TYA or TYA-TYB polyprotein; Gag is
a nucleocapsid protein that is the structural constituent
of virus-like particles (VLPs); similar to retroviral Gag"
/codon_start=1
/product="gag protein"
/protein_id="NP_058159.1"
/db_xref="GI:7839170"
/db_xref="SGD:S000007405"
/db_xref="GeneID:852912"
/translation="MESQQLSQHSHISHGSACASVTSKEVHTNQDPLDVSASKTEECE
KASTKANSQQTTTPASSAVPENPHHASPQTAQSHSPQNGPYPQQCMMTQNQANPSGWS
FYGHPSMIPYTPYQMSPMYFPPGPQSQFPQYPSSVGTPLSTPSPESGNTFTDSSSADS
DMTSTKKYVRPPPMLTSPNDFPNWVKTYIKFLQNSNLGGIIPTVNGKPVRQITDDELT
FLYNTFQIFAPSQFLPTWVKDILSVDYTDIMKILSKSIEKMQSDTQEANDIVTLANLQ
YNGSTPADAFETKVTNIIDRLNNNGIHINNKVACQLIMRGLSGEYKFLRYTRHRHLNM
TVAELFLDIHAIYEEQQGSRNSKPNYRRNLSDEKNDSRSYTNTTKPKVIARNPQKTNN
SKSKTARAHNVSTSNNSPSTDNDSISKSTTEPIQLNNKHDLHLRPGTY"
LTR 541348..541685
/note="Ty1 LTR"
/db_xref="SGD:S000006967"
gene 541850..541921
/locus_tag="tE(UUC)G3"
/db_xref="GeneID:852914"
tRNA 541850..541921
/locus_tag="tE(UUC)G3"
/product="tRNA-Glu"
/note="Glutamate tRNA (tRNA-Glu), predicted by tRNAscan-SE
analysis; thiolation of uridine at wobble position (34)
requires Ncs6p; target of K. lactis zymocin"
/db_xref="SGD:S000006555"
/db_xref="GeneID:852914"
gene 542203..543291
/gene="MSP1"
/locus_tag="YGR028W"
/gene_synonym="YTA4"
/db_xref="GeneID:852915"
mRNA 542203..543291
/gene="MSP1"
/locus_tag="YGR028W"
/gene_synonym="YTA4"
/product="Msp1p"
/transcript_id="NM_001181157.3"
/db_xref="GI:398365222"
/db_xref="GeneID:852915"
CDS 542203..543291
/gene="MSP1"
/locus_tag="YGR028W"
/gene_synonym="YTA4"
/note="Mitochondrial protein involved in sorting of
proteins in the mitochondria; putative membrane-spanning
ATPase"
/codon_start=1
/product="Msp1p"
/protein_id="NP_011542.3"
/db_xref="GI:398365223"
/db_xref="SGD:S000003260"
/db_xref="GeneID:852915"
/translation="MSRKFDLKTITDLSVLVGTGISLYYLVSRLLNDVESGPLSGKSR
ESKAKQSLQWEKLVKRSPALAEVTLDAYERTILSSIVTPDEINITFQDIGGLDPLISD
LHESVIYPLMMPEVYSNSPLLQAPSGVLLYGPPGCGKTMLAKALAKESGANFISIRMS
SIMDKWYGESNKIVDAMFSLANKLQPCIIFIDEIDSFLRERSSTDHEVTATLKAEFMT
LWDGLLNNGRVMIIGATNRINDIDDAFLRRLPKRFLVSLPGSDQRYKILSVLLKDTKL
DEDEFDLQLIADNTKGFSGSDLKELCREAALDAAKEYIKQKRQLIDSGTIDVNDTSSL
KIRPLKTKDFTKKLRMDATSTLSSQPLD"
gene 543553..544205
/gene="ERV1"
/locus_tag="YGR029W"
/db_xref="GeneID:852916"
mRNA join(543553..543638,543722..544205)
/gene="ERV1"
/locus_tag="YGR029W"
/product="Erv1p"
/transcript_id="NM_001181158.3"
/db_xref="GI:398365230"
/db_xref="GeneID:852916"
CDS join(543553..543638,543722..544205)
/gene="ERV1"
/locus_tag="YGR029W"
/EC_number="1.8.3.-"
/note="Flavin-linked sulfhydryl oxidase of the
mitochondrial intermembrane space (IMS), oxidizes Mia40p
as part of a disulfide relay system that promotes IMS
retention of imported proteins; ortholog of human
hepatopoietin (ALR)"
/codon_start=1
/product="Erv1p"
/protein_id="NP_011543.4"
/db_xref="GI:398365231"
/db_xref="SGD:S000003261"
/db_xref="GeneID:852916"
/translation="MKAIDKMTDNPPQEGLSGRKIIYDEDGKPCRSCNTLLDFQYVTG
KISNGLKNLSSNGKLAGTGALTGEASELMPGSRTYRKVDPPDVEQLGRSSWTLLHSVA
ASYPAQPTDQQKGEMKQFLNIFSHIYPCNWCAKDFEKYIRENAPQVESREELGRWMCE
AHNKVNKKLRKPKFDCNFWEKRWKDGWDE"
gene complement(544577..544648)
/locus_tag="tD(GUC)G2"
/db_xref="GeneID:852917"
tRNA complement(544577..544648)
/locus_tag="tD(GUC)G2"
/product="tRNA-Asp"
/note="Aspartate tRNA (tRNA-Asp), predicted by tRNAscan-SE
analysis"
/db_xref="SGD:S000006533"
/db_xref="GeneID:852917"
gene 545370..545566
/locus_tag="snR46"
/db_xref="GeneID:9164897"
ncRNA 545370..545566
/locus_tag="snR46"
/ncRNA_class="snoRNA"
/product="SNR46"
/note="H/ACA box small nucleolar RNA (snoRNA); guides
pseudouridylation of large subunit (LSU) rRNA at position
U2865"
/db_xref="SGD:S000006506"
/db_xref="GeneID:9164897"
gene complement(545681..546157)
/gene="POP6"
/locus_tag="YGR030C"
/db_xref="GeneID:852918"
mRNA complement(545681..546157)
/gene="POP6"
/locus_tag="YGR030C"
/product="Pop6p"
/transcript_id="NM_001181159.1"
/db_xref="GI:296145066"
/db_xref="GeneID:852918"
CDS complement(545681..546157)
/gene="POP6"
/locus_tag="YGR030C"
/EC_number="3.1.26.5"
/note="Subunit of both RNase MRP and nuclear RNase P;
RNase MRP cleaves pre-rRNA, while nuclear RNase P cleaves
tRNA precursors to generate mature 5' ends and facilitates
turnover of nuclear RNAs"
/codon_start=1
/product="Pop6p"
/protein_id="NP_011544.1"
/db_xref="GI:6321467"
/db_xref="SGD:S000003262"
/db_xref="GeneID:852918"
/translation="MINGVYYNEISRDLDISSSTQCLRFLKETVIPSLANNGNNSTSI
QYHGISKNDNIKKSVNKLDKQINMADRSLGLQQVVCIFSYGPHIQKMLSILEIFKKGY
IKNNKKIYQWNKLTSFDIKREGRNELQEERLKVPILVTLVSDSEIIDLNLHSFTKQ"
gene 546441..547469
/gene="IMO32"
/locus_tag="YGR031W"
/db_xref="GeneID:852919"
mRNA 546441..547469
/gene="IMO32"
/locus_tag="YGR031W"
/product="Imo32p"
/transcript_id="NM_001181160.1"
/db_xref="GI:296145067"
/db_xref="GeneID:852919"
CDS 546441..547469
/gene="IMO32"
/locus_tag="YGR031W"
/note="Conserved mitochondrial hypothetical protein;
processed by both mitochondrial processing peptidase and
mitochondrial octapeptidyl aminopeptidase; gene contains
the nested antisense gene NAG1"
/codon_start=1
/product="Imo32p"
/protein_id="NP_011545.1"
/db_xref="GI:6321468"
/db_xref="SGD:S000003263"
/db_xref="GeneID:852919"
/translation="MMILGKAGILAQYGTIYVRQNTIRNNLSSCIFKQSLCAFHSLAK
VLQQKQVPLDLSYDIIKRDAVKTGDEGKPRPPIIILHGLFGNKLNNRSIGRNLNKKLG
RDVYLLDLRNHGSSPHSSVHNYEVMSEDVKHFITKHELNTNGGPIIIGHSMGGKVAMM
LVLKNPQLCSMLVCIENAPVSLRPNAEFVEYIKALMEIVNDKGKTIRTLKQADEHLAE
RIGGNELVRRFLLTALKKVKMDNSSSVSSYTFEERIPLATLKDAIVKGEIAAWPLDPA
RERWTRPALFIRATQSHYVVDEYLPIIGAFFPRFETRDIDAGHWVNAEKPGECAESIV
DFVERHED"
gene complement(546809..547300)
/gene="NAG1"
/locus_tag="YGR031C-A"
/db_xref="GeneID:8656591"
mRNA complement(546809..547300)
/gene="NAG1"
/locus_tag="YGR031C-A"
/product="Nag1p"
/transcript_id="NM_001184658.1"
/db_xref="GI:296148861"
/db_xref="GeneID:8656591"
CDS complement(546809..547300)
/gene="NAG1"
/locus_tag="YGR031C-A"
/note="Protein involved in yeast cell wall biogenesis;
localizes to the cell periphery; production of Nag1p is
dependent upon the presence of Slt2p and Rlm1p; gene is
nested within and antisense to IMO32"
/codon_start=1
/product="Nag1p"
/protein_id="NP_001027023.1"
/db_xref="GI:296148862"
/db_xref="SGD:S000028636"
/db_xref="GeneID:8656591"
/translation="MNSAGRVHRSRAGSRGHAAISPLTMASFSVARGIRSSNVYDDTD
DELSILTFFSAVRRNRLTSSLPPILSARCSSACFSVRIVLPLSLTISISALMYSTNSA
LGRKLTGAFSIQTNIEQSCGFFRTSIMATLPPIECPIIIGPPLVFNSCFVIKCFTSSD
MTS"
gene 548264..553951
/gene="GSC2"
/locus_tag="YGR032W"
/gene_synonym="FKS2"
/db_xref="GeneID:852920"
mRNA 548264..553951
/gene="GSC2"
/locus_tag="YGR032W"
/gene_synonym="FKS2"
/product="Gsc2p"
/transcript_id="NM_001181161.3"
/db_xref="GI:398365250"
/db_xref="GeneID:852920"
CDS 548264..553951
/gene="GSC2"
/locus_tag="YGR032W"
/gene_synonym="FKS2"
/EC_number="2.4.1.34"
/note="Catalytic subunit of 1,3-beta-glucan synthase,
involved in formation of the inner layer of the spore
wall; activity positively regulated by Rho1p and
negatively by Smk1p; has similarity to an alternate
catalytic subunit, Fks1p (Gsc1p)"
/codon_start=1
/product="Gsc2p"
/protein_id="NP_011546.3"
/db_xref="GI:398365251"
/db_xref="SGD:S000003264"
/db_xref="GeneID:852920"
/translation="MSYNDPNLNGQYYSNGDGTGDGNYPTYQVTQDQSAYDEYGQPIY
TQNQLDDGYYDPNEQYVDGTQFPQGQDPSQDQGPYNNDASYYNQPPNMMNPSSQDGEN
FSDFSSYGPPSGTYPNDQYTPSQMSYPDQDGSSGASTPYGNGVVNGNGQYYDPNAIEM
ALPNDPYPAWTADPQSPLPIEQIEDIFIDLTNKFGFQRDSMRNMFDHFMTLLDSRSSR
MSPEQALLSLHADYIGGDTANYKKWYFAAQLDMDDEIGFRNMKLGKLSRKARKAKKKN
KKAMQEASPEDTEETLNQIEGDNSLEAADFRWKSKMNQLSPFEMVRQIALFLLCWGEA
NQVRFTPECLCFIYKCASDYLDSAQCQQRPDPLPEGDFLNRVITPLYRFIRSQVYEIV
DGRYVKSEKDHNKVIGYDDVNQLFWYPEGIAKIVMEDGTRLIDLPAEERYLKLGEIPW
DDVFFKTYKETRSWLHLVTNFNRIWIMHISVYWMYCAYNAPTFYTHNYQQLVDNQPLA
AYKWATAALGGTVASLIQVAATLCEWSFVPRKWAGAQHLSRRFWFLCVIMGINLGPVI
FVFAYDKDTVYSTAAHVVGAVMFFVAVATLVFFSVMPLGGLFTSYMKKSTRSYVASQT
FTASFAPLHGLDRWMSYLVWVTVFAAKYAESYFFLILSLRDPIRILSTTSMRCTGEYW
WGNKICKVQPKIVLGLMIATDFILFFLDTYLWYIVVNTVFSVGKSFYLGISILTPWRN
IFTRLPKRIYSKILATTDMEIKYKPKVLISQIWNAIIISMYREHLLAIDHVQKLLYHQ
VPSEIEGKRTLRAPTFFVSQDDNNFETEFFPRDSEAERRISFFAQSLSTPIPEPLPVD
NMPTFTVLTPHYAERILLSLREIIREDDQFSRVTLLEYLKQLHPVEWDCFVKDTKILA
EETAAYENNEDEPEKEDALKSQIDDLPFYCIGFKSAAPEYTLRTRIWASLRSQTLYRT
ISGFMNYSRAIKLLYRVENPEIVQMFGGNADGLERELEKMARRKFKFLVSMQRLAKFK
PHELENAEFLLRAYPDLQIAYLDEEPPLNEGEEPRIYSALIDGHCEILENGRRRPKFR
VQLSGNPILGDGKSDNQNHALIFYRGEYIQLIDANQDNYLEECLKIRSVLAEFEELGI
EQIHPYTPGLKYEDQSTNHPVAIVGAREYIFSENSGVLGDVAAGKEQTFGTLFARTLA
QIGGKLHYGHPDFINATFMTTRGGVSKAQKGLHLNEDIYAGMNAVLRGGRIKHCEYYQ
CGKGRDLGFGTILNFTTKIGAGMGEQMLSREYYYLGTQLPIDRFLTFYYAHPGFHLNN
LFIQLSLQMFMLTLVNLHALAHESILCVYDRDKPITDVLYPIGCYNFHPAIDWVRRYT
LSIFIVFWIAFVPIVVQELIERGLWKATQRFFRHILSLSPMFEVFAGQIYSSALLSDI
AVGGARYISTGRGFATSRIPFSILYSRFAGSAIYMGSRSMLMLLFGTVAHWQAPLLWF
WASLSALIFAPFIFNPHQFAWEDFFLDYRDYIRWLSRGNNKYHRNSWIGYVRMSRSRV
TGFKRKLVGDESEKSAGDASRAHRTNLIMAEIIPCAIYAAGCFIAFTFINAQTGVKTT
DEDRVNSTLRIIICTLAPIVIDIGVLFFCMGLSCCSGPLLGMCCKKTGSVMAGIAHGI
AVVVHIVFFIVMWVLEGFSFVRMLIGVVTCIQCQRLIFHCMTVLLLTREFKNDHANTA
FWTGKWYSTGLGYMAWTQPTRELTAKVIELSEFAADFVLGHVILIFQLPVICIPKIDK
FHSIMLFWLKPSRQIRPPIYSLKQARLRKRMVRRYCSLYFLVLIIFAGCIVGPAVASA
HVPKDLGSGLTGTFHNLVQPRNVSNNDTGSQMSTYKSHYYTHTPSLKTWSTIK"
gene complement(554248..554967)
/gene="TIM21"
/locus_tag="YGR033C"
/db_xref="GeneID:852921"
mRNA complement(554248..554967)
/gene="TIM21"
/locus_tag="YGR033C"
/product="Tim21p"
/transcript_id="NM_001181162.3"
/db_xref="GI:398365260"
/db_xref="GeneID:852921"
CDS complement(554248..554967)
/gene="TIM21"
/locus_tag="YGR033C"
/note="Nonessential subunit of the Translocase of the
Inner Mitochondrial membrane (TIM23 complex); interacts
with the Translocase of the Outer Mitochondrial membrane
(TOM complex) and with respiratory enzymes; may regulate
TIM23 complex activity"
/codon_start=1
/product="Tim21p"
/protein_id="NP_011547.3"
/db_xref="GI:398365261"
/db_xref="SGD:S000003265"
/db_xref="GeneID:852921"
/translation="MSSSLPRSLLRLGHRKPLFPRYNTFVNSSVITHTSLLRTRLYSN
GTGATSGKKDDKTRNKPKPLWPQVKSASTFTFSGILVIGAVGISAIVIYLILSELFSP
SGDTQLFNRAVSMVEKNKDIRSLLQCDDGITGKERLKAYGELITNDKWTRNRPIVSTK
KLDKEGRTHHYMRFHVESKKKIALVHLEAKESKQNYQPDFINMYVDVPGEKRYYLIKP
KLHPVSNSKGFLGIRWGPRKD"
gene 555812..556672
/gene="RPL26B"
/locus_tag="YGR034W"
/db_xref="GeneID:852922"
mRNA join(555812..555830,556308..556672)
/gene="RPL26B"
/locus_tag="YGR034W"
/product="ribosomal 60S subunit protein L26B"
/transcript_id="NM_001181163.1"
/db_xref="GI:296145070"
/db_xref="GeneID:852922"
CDS join(555812..555830,556308..556672)
/gene="RPL26B"
/locus_tag="YGR034W"
/note="Ribosomal 60S subunit protein L26B; binds to 5.8S
rRNA; homologous to mammalian ribosomal protein L26 and
bacterial L24; RPL26B has a paralog, RPL26A, that arose
from the whole genome duplication"
/codon_start=1
/product="ribosomal 60S subunit protein L26B"
/protein_id="NP_011548.2"
/db_xref="GI:116006491"
/db_xref="SGD:S000003266"
/db_xref="GeneID:852922"
/translation="MAKQSLDVSSDRRKARKAYFTAPSSERRVLLSAPLSKELRAQYG
IKALPIRRDDEVLVVRGSKKGQEGKISSVYRLKFAVQVDKVTKEKVNGASVPINLHPS
KLVITKLHLDKDRKALIQRKGGKLE"
gene complement(557072..557422)
/locus_tag="YGR035C"
/db_xref="GeneID:852923"
mRNA complement(557072..557422)
/locus_tag="YGR035C"
/product="hypothetical protein"
/transcript_id="NM_001181164.1"
/db_xref="GI:296145071"
/db_xref="GeneID:852923"
CDS complement(557072..557422)
/locus_tag="YGR035C"
/note="hypothetical protein, potential Cdc28p substrate;
transcription is activated by paralogous transcription
factors Yrm1p and Yrr1p along with genes involved in
multidrug resistance"
/codon_start=1
/product="hypothetical protein"
/protein_id="NP_011549.1"
/db_xref="GI:6321472"
/db_xref="SGD:S000003267"
/db_xref="GeneID:852923"
/translation="MLLTPAKTTRTEDSANSTDDSSKSSNSFMRAIVSSLMVKPITSL
TNTVTCRQSSHHNSSPSKITRYDLIKAAAENDLKRSKSQGREKSRRNSNRRNNEEIFV
ANTASEIQRTKSSI"
gene 557565..557786
/locus_tag="YGR035W-A"
/db_xref="GeneID:1466457"
mRNA 557565..557786
/locus_tag="YGR035W-A"
/product="hypothetical protein"
/transcript_id="NM_001184648.1"
/db_xref="GI:296145072"
/db_xref="GeneID:1466457"
CDS 557565..557786
/locus_tag="YGR035W-A"
/codon_start=1
/product="hypothetical protein"
/protein_id="NP_878077.1"
/db_xref="GI:33438795"
/db_xref="SGD:S000028827"
/db_xref="GeneID:1466457"
/translation="MLLYLYILYIALKTVSHLFFCNPCFRNLSVGDMLNPRLSLSFFT
NHLLCPEAPLIIRGKGSYSAVGNFFSRKK"
gene complement(558149..558868)
/gene="CAX4"
/locus_tag="YGR036C"
/gene_synonym="CWH8"
/db_xref="GeneID:852924"
mRNA complement(558149..558868)
/gene="CAX4"
/locus_tag="YGR036C"
/gene_synonym="CWH8"
/product="Cax4p"
/transcript_id="NM_001181165.3"
/db_xref="GI:398365284"
/db_xref="GeneID:852924"
CDS complement(558149..558868)
/gene="CAX4"
/locus_tag="YGR036C"
/gene_synonym="CWH8"
/EC_number="3.6.1.43"
/note="Dolichyl pyrophosphate (Dol-P-P) phosphatase with a
luminally oriented active site in the ER, cleaves the
anhydride linkage in Dol-P-P, required for Dol-P-P-linked
oligosaccharide intermediate synthesis and protein
N-glycosylation"
/codon_start=1
/product="Cax4p"
/protein_id="NP_011550.3"
/db_xref="GI:398365285"
/db_xref="SGD:S000003268"
/db_xref="GeneID:852924"
/translation="MNSTAAAINPNPNVIPFDDTYILYDSHDFLSFLSAYFSLMPILV
LAFYLSWFIITRELEACIVAFGQLMNEIFNNVIKNIIKQPRPVSFGASFQNDTIRSGY
GMPSAHSQFMGFCFTYNSLKIYTSWKNLNFLEKCIFSGALALLSFCVCFSRVYLHYHN
LDQVIVGFSVGALTGSLYFFIVGIIRELGLINWFLKLRIVRLFYMTDSYNLAPLTLKE
NYEAYWKRINQRSFNDKSKRD"
gene complement(559731..559994)
/gene="ACB1"
/locus_tag="YGR037C"
/db_xref="GeneID:852925"
mRNA complement(559731..559994)
/gene="ACB1"
/locus_tag="YGR037C"
/product="long-chain fatty acid transporter ACB1"
/transcript_id="NM_001181166.3"
/db_xref="GI:398365290"
/db_xref="GeneID:852925"
CDS complement(559731..559994)
/gene="ACB1"
/locus_tag="YGR037C"
/note="Acyl-CoA-binding protein, transports newly
synthesized acyl-CoA esters from fatty acid synthetase
(Fas1p-Fas2p) to acyl-CoA-consuming processes; subject to
starvation-induced, Grh1p-mediated unconventional
secretion; protein abundance increases in response to DNA
replication stress"
/codon_start=1
/product="long-chain fatty acid transporter ACB1"
/protein_id="NP_011551.3"
/db_xref="GI:398365291"
/db_xref="SGD:S000003269"
/db_xref="GeneID:852925"
/translation="MVSQLFEEKAKAVNELPTKPSTDELLELYALYKQATVGDNDKEK
PGIFNMKDRYKWEAWENLKGKSQEDAEKEYIALVDQLIAKYSS"
gene 560682..561350
/gene="ORM1"
/locus_tag="YGR038W"
/db_xref="GeneID:852926"
mRNA 560682..561350
/gene="ORM1"
/locus_tag="YGR038W"
/product="Orm1p"
/transcript_id="NM_001181167.1"
/db_xref="GI:296145075"
/db_xref="GeneID:852926"
CDS 560682..561350
/gene="ORM1"
/locus_tag="YGR038W"
/note="Evolutionarily conserved protein, similar to Orm2p,
required for resistance to agents that induce unfolded
protein response; Orm1p and Orm2p together control
membrane biogenesis by coordinating lipid homeostasis with
protein quality control"
/codon_start=1
/product="Orm1p"
/protein_id="NP_011552.1"
/db_xref="GI:6321475"
/db_xref="SGD:S000003270"
/db_xref="GeneID:852926"
/translation="MTELDYQGTAEAASTSYSRNQTDLKPFPSAGSASSSIKTTEPVK
DHRRRRSSSIISHVEPETFEDENDQQLLPNMNATWVDQRGAWIIHVVIIILLKLFYNL
FPGVTTEWSWTLTNMTYVIGSYVMFHLIKGTPFDFNGGAYDNLTMWEQIDDETLYTPS
RKFLISVPIALFLVSTHYAHYDLKLFSWNCFLTTFGAVVPKLPVTHRLRISIPGITGR
AQIS"
gene complement(561662..561743)
/locus_tag="tS(AGA)G"
/db_xref="GeneID:852927"
tRNA complement(561662..561743)
/locus_tag="tS(AGA)G"
/product="tRNA-Ser"
/note="Serine tRNA (tRNA-Ser), predicted by tRNAscan-SE
analysis"
/db_xref="SGD:S000006725"
/db_xref="GeneID:852927"
mobile_element complement(561843..567760)
/note="YGRCTy1-2; Ty1 element, LTR retrotransposon of the
Copia (Pseudoviridae) group; contains co-transcribed genes
TYA Gag and TYB Pol, encoding proteins involved in
structure and function of virus-like particles, flanked by
two direct repeats"
/mobile_element_type="retrotransposon:YGRCTy1-2"
/db_xref="SGD:S000006962"
LTR complement(561843..562176)
/note="Ty1 LTR"
/db_xref="SGD:S000006953"
gene complement(562199..567467)
/locus_tag="YGR038C-B"
/db_xref="GeneID:852928"
mRNA complement(join(<562199..566161,566163..>567467))
/locus_tag="YGR038C-B"
/transcript_id="NM_001184434.1"
/db_xref="GI:296145076"
/db_xref="GeneID:852928"
CDS complement(join(562199..566161,566163..567467))
/locus_tag="YGR038C-B"
/EC_number="2.7.7.49"
/EC_number="3.4.23.-"
/EC_number="3.1.26.4"
/EC_number="2.7.7.7"
/ribosomal_slippage
/note="Retrotransposon TYA Gag and TYB Pol genes;
transcribed/translated as one unit; polyprotein is
processed to make a nucleocapsid-like protein (Gag),
reverse transcriptase (RT), protease (PR), and integrase
(IN); similar to retroviral genes"
/codon_start=1
/product="gag-pol fusion protein"
/protein_id="NP_058160.1"
/db_xref="GI:7839173"
/db_xref="SGD:S000007408"
/db_xref="GeneID:852928"
/translation="MESQQLSQHSHISHGSACASVTSKEVHTNQDPLDVSASKIQEYD
KASTKANSQQTTTPASSAVPENPHHASPQPASVPPPQNGPYPQQCMMTQNQANPSGWS
FYGHPSMIPYTPYQMSPMYFPPGPQSQFPQYPSSVGTPLSTPSPESGNTFTDSSSADS
DMTSTKKYVRPPPMLTSPNDFPNWVKTYIKFLQNSNLGGIIPTVNGKPVRQITDDELT
FLYNTFQIFAPSQFLPTWVKDILSVDYTDIMKILSKSIEKMQSDTQEANDIVTLANLQ
YNGSTPADAFETKVTNIIDRLNNNGIHINNKVACQLIMRGLSGEYKFLRYTRHRHLNM
TVAELFLDIHAIYEEQQGSRNSKPNYRRNPSDEKNDSRSYTNTTKPKVIARNPQKTNN
SKSKTARAHNVSTSNNSPSTDNDSISKSTTEPIQLNNKHDLHLGQELTESTVNHTNHS
DDELPGHLLLDSGASRTLIRSAHHIHSASSNPGINVVDAQKRNIPINAIGDLQFHFQD
NTKTSIKVLHTPNIAYDLLSLNELAAVDITACFTKNVLERSDGTVLAPIVKYGDFYWV
SKKYLLPSNISVPTINNVHTSESTRKYPYPFIHRMLAHANAQTIRYSLKNNTITYFNE
SDVDWSSAIDYQCPDCLIGKSTKHRHIKGSRLKYQNSYEPFQYLHTDIFGPVHNLPNS
APSYFISFTDETTKFRWVYPLHDRREDSILDVFTTILAFIKNQFQASVLVIQMDRGSE
YTNRTLHKFLEKNGITPCYTTTADSRAHGVAERLNRTLLDDCRTQLQCSGLPNHLWFS
AIEFSTIVRNSLASPKSKKSARQHAGLAGLDISTLLPFGQPVIVNDHNPNSKIHPRGI
PGYALHPSRNSYGYIIYLPSLKKTVDTTNYVILQGKESRLDQFNYDALTFDEDLNRLT
ASYHSFIASNEIQESNDLNIESDHDFQSDIELHPEQPRNVLSKAVSPTDSTPPSTHTE
DSKRVSKTNIRAPREVDPNISESNILPSKKRSSTPQISNIESTGSGGMHKLNVPLLAP
MSQSNTHESSHASKSKDFRHSDSYSENETNHTNVPISSTGGTNNKTVPQISDQETEKR
IIHRSPSIDASPPENNSSHNIVPIKTPTTVSEQNTEESIIADLPLPDLPPESPTEFPD
PFKELPPINSHQTNSSLGGIGDSNAYTTINSKKRSLEDNETEIKVSRDTWNTKNMRSL
EPPRSKKRIHLIAAVKAVKSIKPIRTTLRYDEAITYNKDIKEKEKYIEAYHKEVNQLL
KMNTWDTDKYYDRKEIDPKRVINSMFIFNRKRDGTHKARFVARGDIQHPDTYDSGMQS
NTVHHYALMTSLSLALDNNYYITQLDISSAYLYADIKEELYIRPPPHLGMNDKLIRLK
KSLYGLKQSGANWYETIKSYLIKQCGMEEVRGWSCVFKNSQVTICLFVDDMILFSKDL
NANKKIITTLKKQYDTKIINLGESDNEIQYDILGLEIKYQRGKYMKLGMENSLTEKIP
KLNVPLNPKGRKLSAPGQPGLYIDQDELEIDEDEYKEKVHEMQKLIGLASYVGYKFRF
DLLYYINTLAQHILFPSRQVLDMTYELIQFMWDTRDKQLIWHKNKPTEPDNKLVAISD
ASYGNQPYYKSQIGNIFLLNGKVIGGKSTKASLTCTSTTEAEIHAVSEAIPLLNNLSH
LVQELNKKPIIKGLLTDSRSTISIIKSTNEEKFRNRFFGTKAMRLRDEVSGNNLYVYY
IETKKNIADVMTKPLPIKTFKLLTNKWIH"
gene complement(566145..567467)
/locus_tag="YGR038C-A"
/db_xref="GeneID:852929"
mRNA complement(<566145..>567467)
/locus_tag="YGR038C-A"
/transcript_id="NM_001184433.1"
/db_xref="GI:296145077"
/db_xref="GeneID:852929"
CDS complement(566145..567467)
/locus_tag="YGR038C-A"
/note="Retrotransposon TYA Gag gene co-transcribed with
TYB Pol; translated as TYA or TYA-TYB polyprotein; Gag is
a nucleocapsid protein that is the structural constituent
of virus-like particles (VLPs); similar to retroviral Gag"
/codon_start=1
/product="gag protein"
/protein_id="NP_058161.1"
/db_xref="GI:7839172"
/db_xref="SGD:S000007407"
/db_xref="GeneID:852929"
/translation="MESQQLSQHSHISHGSACASVTSKEVHTNQDPLDVSASKIQEYD
KASTKANSQQTTTPASSAVPENPHHASPQPASVPPPQNGPYPQQCMMTQNQANPSGWS
FYGHPSMIPYTPYQMSPMYFPPGPQSQFPQYPSSVGTPLSTPSPESGNTFTDSSSADS
DMTSTKKYVRPPPMLTSPNDFPNWVKTYIKFLQNSNLGGIIPTVNGKPVRQITDDELT
FLYNTFQIFAPSQFLPTWVKDILSVDYTDIMKILSKSIEKMQSDTQEANDIVTLANLQ
YNGSTPADAFETKVTNIIDRLNNNGIHINNKVACQLIMRGLSGEYKFLRYTRHRHLNM
TVAELFLDIHAIYEEQQGSRNSKPNYRRNPSDEKNDSRSYTNTTKPKVIARNPQKTNN
SKSKTARAHNVSTSNNSPSTDNDSISKSTTEPIQLNNKHDLHLRPGTY"
LTR complement(567427..567760)
/note="Ty1 LTR"
/db_xref="SGD:S000006954"
rep_origin 568490..568737
/note="ARS721;
Autonomously Replicating Sequence"
/db_xref="SGD:S000118461"
mobile_element complement(568740..574700)
/note="YGRCTy2-1; Ty2 element, LTR retrotransposon of the
Copia (Pseudoviridae) group; contains genes TYA Gag and
TYB Pol, encoding proteins involved in structure and
function of virus-like particles, flanked by two direct
repeats; mutated in S288C"
/mobile_element_type="retrotransposon:YGRCTy2-1"
/db_xref="SGD:S000006964"
LTR complement(568740..569072)
/note="Ty2 LTR"
/db_xref="SGD:S000006955"
LTR complement(574369..574700)
/note="Ty2 LTR"
/db_xref="SGD:S000006956"
rep_origin 574622..574915
/note="ARS722;
Autonomously Replicating Sequence"
/db_xref="SGD:S000118462"
gene 575398..576504
/gene="KSS1"
/locus_tag="YGR040W"
/db_xref="GeneID:852931"
mRNA 575398..576504
/gene="KSS1"
/locus_tag="YGR040W"
/product="Kss1p"
/transcript_id="NM_001181169.3"
/db_xref="GI:398365310"
/db_xref="GeneID:852931"
CDS 575398..576504
/gene="KSS1"
/locus_tag="YGR040W"
/EC_number="2.7.11.24"
/note="Mitogen-activated protein kinase (MAPK) involved in
signal transduction pathways that control filamentous
growth and pheromone response; the KSS1 gene is
nonfunctional in S288C strains and functional in W303
strains"
/codon_start=1
/product="Kss1p"
/protein_id="NP_011554.3"
/db_xref="GI:398365311"
/db_xref="SGD:S000003272"
/db_xref="GeneID:852931"
/translation="MARTITFDIPSQYKLVDLIGEGAYGTVCSAIHKPSGIKVAIKKI
QPFSKKLFVTRTIREIKLLRYFHEHENIISILDKVRPVSIDKLNAVYLVEELMETDLQ
KVINNQNSGFSTLSDDHVQYFTYQILRALKSIHSAQVIHRDIKPSNLLLNSNCDLKVC
DFGLARCLASSSDSRETLVGFMTEYVATRWYRAPEIMLTFQEYTTAMDIWSCGCILAE
MVSGKPLFPGRDYHHQLWLILEVLGTPSFEDFNQIKSKRAKEYIANLPMRPPLPWETV
WSKTDLNPDMIDLLDKMLQFNPDKRISAAEALRHPYLAMYHDPSDEPEYPPLNLDDEF
WKLDNKIMRPEEEEEVPIEMLKDMLYDELMKTME"
rep_origin 575484..576346
/gene="KSS1"
/locus_tag="YGR040W"
/note="ARS723;
Putative replication origin, identified in multiple array
studies, not yet confirmed by plasmid-based assay"
/db_xref="SGD:S000130166"
gene 577487..579130
/gene="BUD9"
/locus_tag="YGR041W"
/db_xref="GeneID:852932"
mRNA 577487..579130
/gene="BUD9"
/locus_tag="YGR041W"
/product="Bud9p"
/transcript_id="NM_001181170.3"
/db_xref="GI:398365314"
/db_xref="GeneID:852932"
CDS 577487..579130
/gene="BUD9"
/locus_tag="YGR041W"
/note="Protein involved in bud-site selection; mutant has
increased aneuploidy tolerance; diploid mutants display a
unipolar budding pattern instead of the wild-type bipolar
pattern, and bud at the distal pole"
/codon_start=1
/product="Bud9p"
/protein_id="NP_011555.3"
/db_xref="GI:398365315"
/db_xref="SGD:S000003273"
/db_xref="GeneID:852932"
/translation="MTKITRDVSITTENSKSTSGSATASSASLPENDHPIFHQPRARI
RSGSLFIEGSDSFPSSEVKSYNVYIDDSKYSEILKGDTNSSSTDGKQVFEDARDDNFH
QESHRDLEDSILDLVRRDPEVAAFPLPPPNSNERNRNSSNGSSAETNLNGHSSSGTIS
TSVLLNMGSAEKHAGTTRGDHMESSSMKSFEKLGTRPSSLFYPPPEGTAPYQGPRATV
SGNKSTRQTQGTYSFPSMRYGVDLVSPVEGAVDVAKSRVPNSTLNGTFPDKAFIPHEF
QIPKKAWNRIPANKSTSLKTPRNHSLLIDILKPFEAADLANDQRSSSAVLKNTVHSNG
QYNPTNETSGTRMQDQRQKNTNEIDLEKIPNPQVPLGIAMDTMRSPNQLHEKEYESNI
EAGLASGVGKGDNSIKQHQYKKIPQEIDRDQQLSFQMETMPIQRIDSSSIRSFDSRIY
GFSEIYSIPRVITTLCICLFVPPLFFFFSINGNNGVSNYRLMRMIMNYEHRIGLLKGF
EWDIDVQWFRTLCFVLGCIEMLAIFASIGIGFGVGIIRE"
gene 579476..580291
/locus_tag="YGR042W"
/db_xref="GeneID:852933"
mRNA 579476..580291
/locus_tag="YGR042W"
/product="hypothetical protein"
/transcript_id="NM_001181171.1"
/db_xref="GI:296145080"
/db_xref="GeneID:852933"
CDS 579476..580291
/locus_tag="YGR042W"
/note="hypothetical protein; involved in maintenance of
proper telomere length; green fluorescent protein
(GFP)-fusion protein localizes to both the cytoplasm and
the nucleus; forms nuclear foci upon DNA replication
stress"
/codon_start=1
/product="hypothetical protein"
/protein_id="NP_011556.1"
/db_xref="GI:6321479"
/db_xref="SGD:S000003274"
/db_xref="GeneID:852933"
/translation="MLSHIVEYECQYTDQLYKKRKIWHDGRLKYFQLNNRFMLYTEKD
NVLLASEFKINSKELKAILNPEGFDIEEHRIFSQFLVIISNIIEEYDRDIQVAATHVR
AYPSNLSVQKQRPLISDNAPSLNHISTAREVHSNIKVTTPNRKQTEDNATKGGFNISK
LTLKVNKPFKKPKRILSTNVVNESNRPSIRSQKIQEVTPQLHETNTSTKVQTAGKVAL
NNDNIAQGNYATITEEAKVRDGSDRKKDMANLSKSGKRRVGGIRRIVHEPLGI"
gene complement(580435..581436)
/gene="NQM1"
/locus_tag="YGR043C"
/db_xref="GeneID:852934"
mRNA complement(580435..581436)
/gene="NQM1"
/locus_tag="YGR043C"
/product="sedoheptulose-7-phosphate:D-glyceraldehyde-3-
phosphate transaldolase NQM1"
/transcript_id="NM_001181172.1"
/db_xref="GI:296145081"
/db_xref="GeneID:852934"
CDS complement(580435..581436)
/gene="NQM1"
/locus_tag="YGR043C"
/EC_number="2.2.1.2"
/note="Transaldolase of unknown function; transcription is
repressed by Mot1p and induced by alpha-factor and during
diauxic shift"
/codon_start=1
/product="sedoheptulose-7-phosphate:D-glyceraldehyde-3-
phosphate transaldolase NQM1"
/protein_id="NP_011557.1"
/db_xref="GI:6321480"
/db_xref="SGD:S000003275"
/db_xref="GeneID:852934"
/translation="MSEPSEKKQKVATSSLEQLKKAGTHVVADSGDFEAISKYEPQDS
TTNPSLILAASKLEKYARFIDAAVEYGRKHGKTDHEKIENAMDKILVEFGTQILKVVP
GRVSTEVDARLSFDKKATVKKALHIIKLYKDAGVPKERVLIKIASTWEGIQAARELEV
KHGIHCNMTLLFSFTQAVACAEANVTLISPFVGRIMDFYKALSGKDYTAETDPGVLSV
KKIYSYYKRHGYATEVMAASFRNLDELKALAGIDNMTLPLNLLEQLYESTDPIENKLN
SESAKEEGVEKVSFINDEPHFRYVLNEDQMATEKLSDGIRKFSADIEALYKLVEEKM"
rep_origin 581436..582213
/note="ARS724;
Putative replication origin, identified in multiple array
studies, not yet confirmed by plasmid-based assay"
/db_xref="SGD:S000130167"
gene complement(582990..583892)
/gene="RME1"
/locus_tag="YGR044C"
/gene_synonym="CSP1"
/db_xref="GeneID:852935"
mRNA complement(582990..583892)
/gene="RME1"
/locus_tag="YGR044C"
/gene_synonym="CSP1"
/product="Rme1p"
/transcript_id="NM_001181173.1"
/db_xref="GI:296145082"
/db_xref="GeneID:852935"
CDS complement(582990..583892)
/gene="RME1"
/locus_tag="YGR044C"
/gene_synonym="CSP1"
/note="Zinc finger protein involved in control of meiosis;
prevents meiosis by repressing IME1 expression and
promotes mitosis by activating CLN2 expression; directly
repressed by a1-alpha2 regulator; mediates cell type
control of sporulation; relocalizes from nucleus to
cytoplasm upon DNA replication stress"
/codon_start=1
/product="Rme1p"
/protein_id="NP_011558.1"
/db_xref="GI:6321481"
/db_xref="SGD:S000003276"
/db_xref="GeneID:852935"
/translation="MSPCYGQNSAIAKGSWNREVLQEVQPIYHWHDFGQNMKEYSASP
LEGDSSLPSSLPSSTEDCLLLSLENTITVIAGNQRQAYDSTSSTEEGTAPQLRPDEIA
DSTHCITSLVDPEFRDLINYGRQKGANPVFIESNTTEQSHSQCILGYPQKSHVAQLYH
DPKVLSTISEGQTKRGSYHCSHCSEKFATLVEFAAHLDEFNLERPCKCPIEQCPWKIL
GFQQATGLRRHCASQHIGELDIEMEKSLNLKVEKYPGLNCPFPICQKTFRRKDAYKRH
VAMVHNNADSRFNKRLKKILNNTK"
gene 584895..586052
/gene="TAM41"
/locus_tag="YGR046W"
/gene_synonym="MMP37"
/db_xref="GeneID:852937"
mRNA 584895..586052
/gene="TAM41"
/locus_tag="YGR046W"
/gene_synonym="MMP37"
/product="Tam41p"
/transcript_id="NM_001181175.3"
/db_xref="GI:398365344"
/db_xref="GeneID:852937"
CDS 584895..586052
/gene="TAM41"
/locus_tag="YGR046W"
/gene_synonym="MMP37"
/note="Mitochondrial protein required for cardiolipin
biosynthesis; viability of null mutant is
strain-dependent; mRNA is targeted to the bud; mutant
displays defect in mitochondrial protein import, likely
due to altered membrane lipid composition"
/codon_start=1
/product="Tam41p"
/protein_id="NP_011560.3"
/db_xref="GI:398365345"
/db_xref="SGD:S000003278"
/db_xref="GeneID:852937"
/translation="MLRVSENGLRFLLKCHSTNVSMFNRLLSTQIKEGRSSIDDAGII
PDGTINERPNHYIEGITKGSDLDLLEKGIRKTDEMTSNFTNYMYKFHRLPPNYGSNQL
ITIDKELQKELDGVMSSFKAPCRFVFGYGSGVFEQAGYSKSHSKPQIDIILGVTYPSH
FHSINMRQNPQHYSSLKYFGSEFVSKFQQIGAGVYFNPFANINGHDVKYGVVSMETLL
KDIATWNTFYLAGRLQKPVKILKNDLRVQYWNQLNLKAAATLAKHYTLEKNNNKFDEF
QFYKEITALSYAGDIRYKLGGENPDKVNNIVTKNFERFQEYYKPIYKEVVLNDSFYLP
KGFTLKNTQRLLLSRISKSSALQTIKGVFTAGITKSIKYAWAKKLKSMRRS"
gene complement(586392..589469)
/gene="TFC4"
/locus_tag="YGR047C"
/gene_synonym="PCF1"
/db_xref="GeneID:852938"
mRNA complement(586392..589469)
/gene="TFC4"
/locus_tag="YGR047C"
/gene_synonym="PCF1"
/product="Tfc4p"
/transcript_id="NM_001181176.3"
/db_xref="GI:398365352"
/db_xref="GeneID:852938"
CDS complement(586392..589469)
/gene="TFC4"
/locus_tag="YGR047C"
/gene_synonym="PCF1"
/note="One of six subunits of the RNA polymerase III
transcription initiation factor complex (TFIIIC); part of
the TauA domain of TFIIIC that binds BoxA DNA promoter
sites of tRNA and similar genes; has TPR motifs; human
homolog is TFIIIC-102"
/codon_start=1
/product="Tfc4p"
/protein_id="NP_011561.3"
/db_xref="GI:398365353"
/db_xref="SGD:S000003279"
/db_xref="GeneID:852938"
/translation="MAAGKLKKEQQNQSAERESADTGKVNDEDEEHLYGNIDDYKHLI
QDEEYDDEDVPHDLQLSEDEYNSERDSSLLAEFSDYGEISEDDEEDFMNAIREASNFK
VKKKKKNDKGKSYGRQRKERVLDPEVAQLLSQANEAFVRNDLQVAERLFNEVIKKDAR
NFAAYETLGDIYQLQGRLNDCCNSWFLAAHLNASDWEFWKIVAILSADLDHVRQAIYC
FSRVISLNPMEWESIYRRSMLYKKTGQLARALDGFQRLYMYNPYDANILRELAILYVD
YDRIEDSIELYMKVFNANVERREAILAALENALDSSDEESAAEGEDADEKEPLEQDED
RQMFPDINWKKIDAKYKCIPFDWSSLNILAELFLKLAVSEVDGIKTIKKCARWIQRRE
SQTFWDHVPDDSEFDNRRFKNSTFDSLLAAEKEKSYNIPIDIRVRLGLLRLNTDNLVE
ALNHFQCLYDETFSDVADLYFEAATALTRAEKYKEAIDFFTPLLSLEEWRTTDVFKPL
ARCYKEIESYETAKEFYELAIKSEPDDLDIRVSLAEVYYRLNDPETFKHMLVDVVEMR
KHQVDETLHRISNEKSSNDTSDISSKPLLEDSKFRTFRKKKRTPYDAERERIERERRI
TAKVVDKYEKMKKFELNSGLNEAKQASIWINTVSELVDIFSSVKNFFMKSRSRKFVGI
LRRTKKFNTELDFQIERLSKLAEGDSVFEGPLMEERVTLTSATELRGLSYEQWFELFM
ELSLVIAKYQSVEDGLSVVETAQEVNVFFQDPERVKMMKFVKLAIVLQMDDEEELAEN
LRGLLNQFQFNRKVLQVFMYSLCRGPSSLNILSSTIQQKFFLRQLKAFDSCRYNTEVN
GQASITNKEVYNPNKKSSPYLYYIYAVLLYSSRGFLSALQYLTRLEEDIPDDPMVNLL
MGLSHIHRAMQRLTAQRHFQIFHGLRYLYRYHKIRKSLYTDLEKQEADYNLGRAFHLI
GLVSIAIEYYNRVLENYDDGKLKKHAAYNSIIIYQQSGNVELADHLMEKYLSI"
gene 589826..590911
/gene="UFD1"
/locus_tag="YGR048W"
/db_xref="GeneID:852939"
mRNA 589826..590911
/gene="UFD1"
/locus_tag="YGR048W"
/product="polyubiquitin-binding protein UFD1"
/transcript_id="NM_001181177.1"
/db_xref="GI:296145085"
/db_xref="GeneID:852939"
CDS 589826..590911
/gene="UFD1"
/locus_tag="YGR048W"
/note="Substrate-recruiting cofactor of the
Cdc48p-Npl4p-Ufd1p segregase; polyubiquitin binding
protein that assists in the dislocation of misfolded, ERAD
substrates that are subsequently delivered to the
proteasome for degradation; involved in regulated
destruction of ER membrane proteins such as HMG-CoA
reductase (Hmg1/2p) and cytoplasmic proteins (Fbp1p);
involved in mobilizing membrane bound transaction factors
by regulated Ub/proteasome-dependent processing (RUP)"
/codon_start=1
/product="polyubiquitin-binding protein UFD1"
/protein_id="NP_011562.1"
/db_xref="GI:6321485"
/db_xref="SGD:S000003280"
/db_xref="GeneID:852939"
/translation="MFSGFSSFGGGNGFVNMPQTFEEFFRCYPIAMMNDRIRKDDANF
GGKIFLPPSALSKLSMLNIRYPMLFKLTANETGRVTHGGVLEFIAEEGRVYLPQWMME
TLGIQPGSLLQISSTDVPLGQFVKLEPQSVDFLDISDPKAVLENVLRNFSTLTVDDVI
EISYNGKTFKIKILEVKPESSSKSICVIETDLVTDFAPPVGYVEPDYKALKAQQDKEK
KNSFGKGQVLDPSVLGQGSMSTRIDYAGIANSSRNKLSKFVGQGQNISGKAPKAEPKQ
DIKDMKITFDGEPAKLDLPEGQLFFGFPMVLPKEDEESAAGSKSSEQNFQGQGISLRK
SNKRKTKSDHDSSKSKAPKSPEVIEID"
gene 591314..591877
/gene="SCM4"
/locus_tag="YGR049W"
/db_xref="GeneID:852940"
mRNA 591314..591877
/gene="SCM4"
/locus_tag="YGR049W"
/product="Scm4p"
/transcript_id="NM_001181178.1"
/db_xref="GI:296145086"
/db_xref="GeneID:852940"
CDS 591314..591877
/gene="SCM4"
/locus_tag="YGR049W"
/note="Mitochondrial outer membrane hypothetical protein;
predicted to have 4 transmembrane segments; import is
mediated by Tom70p and Mim1p; interacts genetically with a
cdc4 mutation"
/codon_start=1
/product="Scm4p"
/protein_id="NP_011563.1"
/db_xref="GI:6321486"
/db_xref="SGD:S000003281"
/db_xref="GeneID:852940"
/translation="MQVSPAIVKGIAVSSLGLYAGILTSSTVISITTPINVLTQHLKN
VLCTLGCWSTVLGGLATGAFGLSYYLAAPGERPNYLLCGLGVAPLSAAYLYLVSLFNH
KLAPKCTRDQNDLEKQKDEKLPQHHPEVKDGEAACPFSKMNNAKTLKPESERSVKCHS
YMSLHMSIVTGITIFTFGKCILDGFKA"
gene complement(592086..592442)
/locus_tag="YGR050C"
/db_xref="GeneID:852941"
mRNA complement(592086..592442)
/locus_tag="YGR050C"
/product="hypothetical protein"
/transcript_id="NM_001270748.1"
/db_xref="GI:398365372"
/db_xref="GeneID:852941"
CDS complement(592086..592442)
/locus_tag="YGR050C"
/note="hypothetical protein; mRNA identified as translated
by ribosome profiling data"
/codon_start=1
/product="hypothetical protein"
/protein_id="NP_001257677.1"
/db_xref="GI:398365373"
/db_xref="SGD:S000003282"
/db_xref="GeneID:852941"
/translation="MKTNLISSFAFRPHVRFGFLDFGYSLKSILDVTSQYHFIPIKLA
YGLCDPLLIVYPDPSFSLAQAAGEKKKVVFPTYEDVPKLLLTFKQIMNTYRKGSLGQR
QRQRVYGRNGNESHST"
gene 593596..594705
/gene="FMP48"
/locus_tag="YGR052W"
/db_xref="GeneID:852943"
mRNA 593596..594705
/gene="FMP48"
/locus_tag="YGR052W"
/product="Fmp48p"
/transcript_id="NM_001181181.1"
/db_xref="GI:296145087"
/db_xref="GeneID:852943"
CDS 593596..594705
/gene="FMP48"
/locus_tag="YGR052W"
/note="hypothetical protein; the authentic, non-tagged
protein is detected in highly purified mitochondria in
high-throughput studies; induced by treatment with
8-methoxypsoralen and UVA irradiation"
/codon_start=1
/product="Fmp48p"
/protein_id="NP_011566.1"
/db_xref="GI:6321489"
/db_xref="SGD:S000003284"
/db_xref="GeneID:852943"
/translation="MYTKLRSIQSGTFSTVYKAWSTTHNRYVALKITPKYKTSEANMK
NEYDVMKILSSCNPHPNICSMLDFYTDDSYYIMVLEYCECGDLYDFLDIAKSQGSPSS
PSLIQIDMQKIIKQLCSAISFAHSLGIAHRDIKPENILLTINGDIKLADWGHAIQSPK
SNDFQIGTDNYRAPETFSGRVSNSCFKKNFDRSSAPLYNTYQADYWSLGATIFYLMFG
DCLFRVSKSKKVQHLKNFDEFEKDPFAFIYRKYVVPRLSCGYNDEEDLHVSLQHTRQY
IWQDLPDIYDVFHLCKIMVDTLLKVSNAKERSMENFINEVDSAWNKDSSMDSCFSYQN
KIDLFWEQWSVNTETVPAKFQLKNFEKPCLIQDGK"
gene complement(594986..595837)
/locus_tag="YGR053C"
/db_xref="GeneID:852944"
mRNA complement(594986..595837)
/locus_tag="YGR053C"
/product="hypothetical protein"
/transcript_id="NM_001181182.3"
/db_xref="GI:398365388"
/db_xref="GeneID:852944"
CDS complement(594986..595837)
/locus_tag="YGR053C"
/codon_start=1
/product="hypothetical protein"
/protein_id="NP_011567.3"
/db_xref="GI:398365389"
/db_xref="SGD:S000003285"
/db_xref="GeneID:852944"
/translation="MLLKCVCRAGIISIKGIFPRWYSNSQKVANLGQITDYLVVKGVP
NLLQKMFKESVLADNVVFRLFPTSHPYIPVLHGKSKYMASLNAMRMIVRKFILGDECR
LHISSVKTLTSTSHDEEVKSALQSYNTITCNDKLVIKWQSCIPEDHCKITKLEINDRL
KEEKRGNGAGGSFSMRSVPVIDYILHPTANNLNQSVISEYLENAAERSMENKVNETQN
SKEDEKKKNDGDGKRSKKKRLSRLIKGTFIFEFNEENSKILVHTIEDVELIHYEKKIA
TRGAFAC"
gene 596693..598621
/locus_tag="YGR054W"
/db_xref="GeneID:852945"
mRNA 596693..598621
/locus_tag="YGR054W"
/product="hypothetical protein"
/transcript_id="NM_001181183.4"
/db_xref="GI:398365396"
/db_xref="GeneID:852945"
CDS 596693..598621
/locus_tag="YGR054W"
/note="Eukaryotic initiation factor (eIF) 2A; associates
specifically with both 40S subunits and 80 S ribosomes,
and interacts genetically with both eIF5b and eIF4E;
homologous to mammalian eIF2A"
/codon_start=1
/product="hypothetical protein"
/protein_id="NP_011568.3"
/db_xref="GI:398365397"
/db_xref="SGD:S000003286"
/db_xref="GeneID:852945"
/translation="MSSQFFLKTSQDIELFQSYPTFEQSNTNSKDFPVISSVLSPCGR
FLALSTKENVKVFTGPCLDNVLLTMKLSDVYDLHFSPAGNYLSTWERASIQDPNHKNV
KVWYLNKPFKKDCVSEDIVPAYEYQAKSQSGWFLQFSKLDNYGLRLFKHDLKIVKLSS
ANADNFDFQSPFAVLSDDETSQHFTTYLISPAEHPTICTFTPEKGGKPAQLIIWALSE
GKITKKIASKTFFKADSCQLKWNPLGNAILCLAITDFDSSNKSYYGENTLYLLSFQGV
NGTLGGNSVRVSLTTGPVHDFTWSPTSRQFGVIAGYMPATISFFDLRGNVVHSLPQQA
KNTMLFSPSGHYILIAGFGNLQGSVEILDRLDKFKCVSKFDATNTSVCKWSPGGEFIM
TATTSPRLRVDNGVKIWHVSGSLVFVKEFKELLKVDWRSPCNYKTLENKDEAFFENHI
INNWEPLPDSTTSSLDPKISNKSELQIHSSVQEYISQHPSREASSNGNGSKAKAGGAY
KPPHARRTGGGRIVPGVPPGAAKKTIPGLVPGMSANKDANTKNRRRRANKKSSETSPD
STPAPSAPASTNAPTNNKETSPEEKKIRSLLKKLRAIETLKERQAVGDKLEDTQVLKI
QTEEKVLKDLEKLGWKDE"
gene 599417..601141
/gene="MUP1"
/locus_tag="YGR055W"
/db_xref="GeneID:852946"
mRNA 599417..601141
/gene="MUP1"
/locus_tag="YGR055W"
/product="Mup1p"
/transcript_id="NM_001181184.1"
/db_xref="GI:296145090"
/db_xref="GeneID:852946"
CDS 599417..601141
/gene="MUP1"
/locus_tag="YGR055W"
/note="High affinity methionine permease, integral
membrane protein with 13 putative membrane-spanning
regions; also involved in cysteine uptake"
/codon_start=1
/product="Mup1p"
/protein_id="NP_011569.1"
/db_xref="GI:6321492"
/db_xref="SGD:S000003287"
/db_xref="GeneID:852946"
/translation="MSEGRTFLSQLNVFNKENYQFSSSTTKKEVSNSTVDADNGASDF
EAGQQFATELDQGEKQLGILSCIGLICNRMLGTGVFAVSSTIYTLCGSVGLALIMWAV
GAIIAISGLYVYMEFGTAIPKNGGEKNYLEAIFRKPKFFITCMYAAYIFFLGWAAGNS
INTAIMFLTAADTEVTKWNQRGIGVAVVFFAFLINSLNVKIGLYLQNILGIFKIGIVL
FISITGWVALGGGLKDGYQSHNFRNAFEGTETATAYGIVNALYSVIWSFVGYSNVNYA
LGEVKNPVRTLKIAGPTSMVFLAIIYIFVNIAYFAVVPKDKLISSKLILAADFFDIVF
GGQAKRAAAALVGLSALGNVLSVIFSQGRIIQQLGREGVLPFSNFFASSKPFNSPMVG
LFQHFIVCTVTILAPPPGDAYLLVQNLISYPMNIINFAISAGLLWIYWQRRQGKIEWN
PPIKAGVFVTGFFTLSNLYLIIAPYVPPSNGESVYSSMPYWIHCVIAWGIFFFGGVYY
VVWAQLLPRWGHYKLVSKDVLGEDGFWRVKIAKVYDDTIGDVDTQEDGVIETNIIEHY
KSEQEKSL"
gene 601661..604447
/gene="RSC1"
/locus_tag="YGR056W"
/db_xref="GeneID:852947"
mRNA 601661..604447
/gene="RSC1"
/locus_tag="YGR056W"
/product="Rsc1p"
/transcript_id="NM_001181185.1"
/db_xref="GI:296145091"
/db_xref="GeneID:852947"
CDS 601661..604447
/gene="RSC1"
/locus_tag="YGR056W"
/note="Component of the RSC chromatin remodeling complex;
required for expression of mid-late sporulation-specific
genes; contains two essential bromodomains, a
bromo-adjacent homology (BAH) domain, and an AT hook"
/codon_start=1
/product="Rsc1p"
/protein_id="NP_011570.1"
/db_xref="GI:6321493"
/db_xref="SGD:S000003288"
/db_xref="GeneID:852947"
/translation="MVEQDNGFLQKLLKTQYDAVFHLKDENGIEIYPIFNVLPPKKEY
PDYYIIIRNPISLNTLKKRLPHYTSPQDFVNDFAQIPWNAMTYNAKDSVIYKYAILLE
SFIKGKIVHNIRKHYPEVTYPSLGRIPEIFAESMQPSDLSSNPINTQENDEKAGLNPE
MKMAFAKLDSSITERKPTNQDYRMQQKNSPAFPTHSASITPQPLASPTPVVNYANITS
AHPKTHVRRGRPPVIDLPYVLRIKNILKMMRREVDQNNKTLTLCFEKLPDRNEEPTYY
SVITDPICLMDIRKKVKSRKYRNFHTFEEDFQLMLTNFKLYYSQDQSNIIRAQLLEKN
FNRLVRIELSKPDEDYLPEGELRYPLDDVEINDEKYQIGDWVLLHNPNDINKPIVGQI
FRLWSTTDGNKWLNACWYFRPEQTVHRVDRLFYKNEVMKTGQYRDHPIQDIKGKCYVI
HFTRFQRGDPSTKVNGPQFVCEFRYNESDKVFNKIRTWKACLPEELRDQDEPTIPVNG
RKFFKYPSPIADLLPANATLNDKVPEPTEGAPTAPPLVGAVYLGPKLERDDLGEYSTS
DDCPRYIIRPNDPPEEGKIDYETGTIITDTLTTSSMPRVNSSSTIRLPTLKQTKSIPS
SNFRSSSNTPLLHQNFNQTSNFLKLENMNNSSHNLLSHPSVPKFQSPSLLEQSSRSKY
HSAKKQTQLSSTAPKKPASKSFTLSSMINTLTAHTSKYNFNHIVIEAPGAFVVPVPME
KNIRTIQSTERFSRSNLKNAQNLGNTAINDINTANEQIIWFKGPGVKITERVIDSGND
LVRVPLNRWFCKNKRRKLDYEDIEEDVMEPPNDFSEDMIANIFNPPPSLNLDMDLNLS
PSSNNSSNFMDLSTIASGDNDGKECDTAEESEDENEDTEDEHEIEDIPTTSAFGLNSS
AEYLAFRLREFNKL"
gene complement(604773..605501)
/gene="LST7"
/locus_tag="YGR057C"
/db_xref="GeneID:852948"
mRNA complement(604773..605501)
/gene="LST7"
/locus_tag="YGR057C"
/product="Lst7p"
/transcript_id="NM_001181186.3"
/db_xref="GI:398365412"
/db_xref="GeneID:852948"
CDS complement(604773..605501)
/gene="LST7"
/locus_tag="YGR057C"
/note="Protein possibly involved in a post-Golgi secretory
pathway; required for the transport of nitrogen-regulated
amino acid permease Gap1p from the Golgi to the cell
surface"
/codon_start=1
/product="Lst7p"
/protein_id="NP_011571.4"
/db_xref="GI:398365413"
/db_xref="SGD:S000003289"
/db_xref="GeneID:852948"
/translation="MSSTVISLAHFCDKHGPRIISVTQSAEKGTLGEELLVPDYPTES
YCESCLLQFPEESTRSMRCFIEDVPFITTQYSSIRYQLLNSIIKRAFSEETMIYDNMP
FIFFDDLRGLNLVIGFKLYDENARGNERRYCFILTVDSRSHDDSMKMLSEHWNFIIGG
FDKMIAYIKNIHKSEFLGKNKTVENNLETLNNNAFIGSYLRANKSKFGRNLVSLTDDK
FLFVRIHKWNSFLLHTVMNENKLP"
gene 606136..607143
/gene="PEF1"
/locus_tag="YGR058W"
/db_xref="GeneID:852949"
mRNA 606136..607143
/gene="PEF1"
/locus_tag="YGR058W"
/product="Pef1p"
/transcript_id="NM_001181187.2"
/db_xref="GI:330443561"
/db_xref="GeneID:852949"
CDS 606136..607143
/gene="PEF1"
/locus_tag="YGR058W"
/note="Penta-EF-hand protein required for polar bud growth
and cell wall abscission; binds calcium and zinc with
different affinity; localizes to bud site in G1, bud neck
in G2; binds to Sec31p and modulates COPII coat assembly"
/codon_start=1
/product="Pef1p"
/protein_id="NP_011572.2"
/db_xref="GI:330443562"
/db_xref="SGD:S000003290"
/db_xref="GeneID:852949"
/translation="MCAKKLKYAAGDDFVRYATPKEAMEETRREFEKEKQRQQQIKVT
QAQTPNTRVHSAPIPLQTQYNKNRAENGHHSYGSPQSYSPRHTKTPVDPRYNVIAQKP
AGRPIPPAPTHYNNLNTSAQRIASSPPPLIHNQAVPAQLLKKVAPASFDSREDVRDMQ
VATQLFHNHDVKGKNRLTAEELQNLLQNDDNSHFCISSVDALINLFGASRFGTVNQAE
FIALYKRVKSWRKVYVDNDINGSLTISVSEFHNSLQELGYLIPFEVSEKTFDQYAEFI
NRNGTGKELKFDKFVEALVWLMRLTKLFRKFDTNQEGIATIQYKDFIDATLYLGRFLP
H"
gene 607563..609101
/gene="SPR3"
/locus_tag="YGR059W"
/db_xref="GeneID:852950"
mRNA 607563..609101
/gene="SPR3"
/locus_tag="YGR059W"
/product="septin SPR3"
/transcript_id="NM_001181188.3"
/db_xref="GI:398365430"
/db_xref="GeneID:852950"
CDS 607563..609101
/gene="SPR3"
/locus_tag="YGR059W"
/note="Sporulation-specific homolog of the yeast
CDC3/10/11/12 family of bud neck microfilament genes;
septin protein involved in sporulation; regulated by ABFI"
/codon_start=1
/product="septin SPR3"
/protein_id="NP_011573.3"
/db_xref="GI:398365431"
/db_xref="SGD:S000003291"
/db_xref="GeneID:852950"
/translation="MKSKGSRLSTDCPVEFPKIVSGFAEEVKIRRQSSQGQYAVDSHP
PKSPELKHRRQRSSSFVNGKCRNRDLPLLDNKKAQEINTNSHGQDIGIKNLPRQRELL
NAKNGIDFTLMVAGQSGLGKTTFINSLFSTSLIDDDIKENKPIIRYKSIVEGDGTHLN
FNVIDTPGFGNNMDNAFTWRTMVNYIDEEIRSYIFQEEQPDRTKMVDNRVHCCLYFLR
PSNKGIDTLDVVTMKKLAKRVNLIPVIAKSDLLTKEELKNFKTQVREIIRVQDIPVCF
FFGDEVLNATQDIFQKYPFSIIASNEYIFNEKGEKVKGRQYKWGAVDIENEKYCDFKI
LQKTIFDWNLIDLVESTEDYYEKCRSEMLRTRLLKARDCLTTKSVDITEEQRKFLEEE
MNFDEIEENKLKNYKCYEIINKTVMDKVATEWDPEFITRQLEAKKKFNELSNREISKF
RDWKKSLFMEQENFNQEIEQLNHKLENLQLECQDLEYKLLIGKSSNSHSTDSATLVNV
HIKR"
gene 609584..609696
/locus_tag="snR48"
/db_xref="GeneID:9164898"
ncRNA 609584..609696
/locus_tag="snR48"
/ncRNA_class="snoRNA"
/product="SNR48"
/note="C/D box small nucleolar RNA (snoRNA), guides
2'-O-methylation of large subunit (LSU) rRNA at positions
G2791 and G2793"
/db_xref="SGD:S000006440"
/db_xref="GeneID:9164898"
gene 610564..611493
/gene="ERG25"
/locus_tag="YGR060W"
/db_xref="GeneID:852951"
mRNA 610564..611493
/gene="ERG25"
/locus_tag="YGR060W"
/product="methylsterol monooxygenase"
/transcript_id="NM_001181189.3"
/db_xref="GI:398365434"
/db_xref="GeneID:852951"
CDS 610564..611493
/gene="ERG25"
/locus_tag="YGR060W"
/EC_number="1.14.13.72"
/note="C-4 methyl sterol oxidase, catalyzes the first of
three steps required to remove two C-4 methyl groups from
an intermediate in ergosterol biosynthesis; mutants
accumulate the sterol intermediate 4,4-dimethylzymosterol"
/codon_start=1
/product="methylsterol monooxygenase"
/protein_id="NP_011574.3"
/db_xref="GI:398365435"
/db_xref="SGD:S000003292"
/db_xref="GeneID:852951"
/translation="MSAVFNNATLSGLVQASTYSQTLQNVAHYQPQLNFMEKYWAAWY
SYMNNDVLATGLMFFLLHEFMYFFRCLPWFIIDQIPYFRRWKLQPTKIPSAKEQLYCL
KSVLLSHFLVEAIPIWTFHPMCEKLGITVEVPFPSLKTMALEIGLFFVLEDTWHYWAH
RLFHYGVFYKYIHKQHHRYAAPFGLSAEYAHPAETLSLGFGTVGMPILYVMYTGKLHL
FTLCVWITLRLFQAVDSHSGYDFPWSLNKIMPFWAGAEHHDLHHHYFIGNYASSFRWW
DYCLDTESGPEAKASREERMKKRAENNAQKKTN"
gene complement(611889..615965)
/gene="ADE6"
/locus_tag="YGR061C"
/db_xref="GeneID:852952"
mRNA complement(611889..615965)
/gene="ADE6"
/locus_tag="YGR061C"
/product="phosphoribosylformylglycinamidine synthase"
/transcript_id="NM_001181190.1"
/db_xref="GI:296145096"
/db_xref="GeneID:852952"
CDS complement(611889..615965)
/gene="ADE6"
/locus_tag="YGR061C"
/EC_number="6.3.5.3"
/note="Formylglycinamidine-ribonucleotide
(FGAM)-synthetase, catalyzes a step in the 'de novo'
purine nucleotide biosynthetic pathway"
/codon_start=1
/product="phosphoribosylformylglycinamidine synthase"
/protein_id="NP_011575.1"
/db_xref="GI:6321498"
/db_xref="SGD:S000003293"
/db_xref="GeneID:852952"
/translation="MTDYILPGPKALSQFRVDNLIKDINSYTNSTSVINELRSCYIHY
VNGIAQNLSEQDTKLLEVLLTYDSALDIANDPLARQLNDAVANNLPSSALGEDTYLIR
VVPRSGTISPWSSKATNIAHVCGLQDKVQRIERGLALLIKTVPGFPLLENLNDISLKC
VYDRMTQQLYLTEPPNTMSIFTHEEPKPLVHVPLTPKDTKQSPKDILSKANTELGLAL
DSGEMEYLIHAFVETMKRDPTDVELFMFAQVNSEHCRHKIFNADWTIDGIKQQFTLFQ
MIRNTHKLNPEYTISAYSDNAAVLDSENDAFFFAPNSTTKEWTSTKERIPLLIKVETH
NHPTAVSPFPGAATGSGGEIRDEGATGRGSKTKCGLSGFSVSDLLIPGNEQPWELNIG
KPYHIASALDIMIEAPLGSAAFNNEFGRPCINGYFRTLTTKVLNHQGKEEIRGFHKPI
MIAGGFGTVRPQFALKNTPITPGSCLIVLGGQSMLIGLGGGAASSVASGEGSADLDFA
SVQRGNPEMERRCQQVIDACVALGNNNPIQSIHDVGAGGLSNALPELVHDNDLGAKFD
IRKVLSLEPGMSPMEIWCNESQERYVLGVSPQDLSIFEEICKRERAPFAVVGHATAEQ
KLIVEDPLLKTTPIDLEMPILFGKPPKMSRETITEALNLPEANLSEIPSLQDAIQRVL
NLPSVGSKSFLITIGDRSVTGLIDRDQFVGPWQVPVADVGVTGTSLGETIISTGEAMA
MGEKPVNALISASASAKLSVAESLLNIFAADVKSLNHIKLSANWMSPASHQGEGSKLY
EAVQALGLDLCPALGVAIPVGKDSMSMKMKWDDKEVTAPLSLNITAFAPVFNTSKTWT
PLLNRNTDDSVLVLVDLSAKQETKSLGASALLQVYNQVGNKSPTVYDNAILKGFLESL
IQLHQQKEDIVLAYHDRSDGGLLITLLEMAFASRCGLEINIDGGDLESQLTNLFNEEL
GAVFQISAKNLSKFEKILNENGVAKEYISIVGKPSFQSQEIKIINSTTNDVIYANSRS
ELEQTWSKTSYEMQKLRDNPKTAEEEFASITDDRDPGLQYALTYNPADDMKIGLELSS
QRPKVAILREQGVNGQMEMAWCFQQAGFNSVDVTMTDLLEGRFHLDDFIGLAACGGFS
YGDVLGAGAGWAKSVLYHEGVRSQFSKFFNERQDTFAFGACNGCQFLSRLKDIIPGCE
NWPSFERNVSEQYEARVCMVQISQEKDNSSEESVFLNGMAGSKLPIAVAHGEGKATFS
KSAEQLEKFEKDGLCCIRYVDNYGNVTERFPFNPNGSTNGIAGIKSPNGRVLAMMPHP
ERVCRLEANSWYPEGKYEEWGGYGPWIRLFRSARRWVG"
gene complement(616328..617278)
/gene="COX18"
/locus_tag="YGR062C"
/gene_synonym="OXA2"
/db_xref="GeneID:852953"
mRNA complement(616328..617278)
/gene="COX18"
/locus_tag="YGR062C"
/gene_synonym="OXA2"
/product="Cox18p"
/transcript_id="NM_001181191.1"
/db_xref="GI:296145097"
/db_xref="GeneID:852953"
CDS complement(616328..617278)
/gene="COX18"
/locus_tag="YGR062C"
/gene_synonym="OXA2"
/note="Mitochondrial integral inner membrane protein
required for membrane insertion of C-terminus of Cox2p;
interacts genetically and physically with Mss2p and Pnt1p;
similar to S. cerevisiae Oxa1, N. crassa Oxa2p, and E.
coli YidC"
/codon_start=1
/product="Cox18p"
/protein_id="NP_011576.1"
/db_xref="GI:6321499"
/db_xref="SGD:S000003294"
/db_xref="GeneID:852953"
/translation="MLKRLANRQNGFASFSCSSVGLRYGRTNPSTKRSFSLFQSVADT
FLTVHEASHIPWIVLVPLTTMTLRTLVTLPFSIWQRRRILKQQELRKLVQPITPIIKL
RLAAVTNKKSRNAARISSNGSFMPLQLQNAGVLTPEQITLLAVKETRKRQKKLFKKYN
VPLWKNALLPMVQIPLWVTVSMGIRTLTETQLIESFYPSWFSALGFSSFDLSSPLVAM
PLLAPILVGTLAVLNVELNGRLMFSSSLSSQGIKTISRNSTRVQEAMTSILNVSRLGC
VVMLAMSSQAPFLLSLYWISSQLFSLVQNIILNWIYPYQR"
gene complement(617516..617824)
/gene="SPT4"
/locus_tag="YGR063C"
/db_xref="GeneID:852955"
mRNA complement(617516..617824)
/gene="SPT4"
/locus_tag="YGR063C"
/product="Spt4p"
/transcript_id="NM_001181192.3"
/db_xref="GI:398365456"
/db_xref="GeneID:852955"
CDS complement(617516..617824)
/gene="SPT4"
/locus_tag="YGR063C"
/note="Component of the universally conserved Spt4/5
complex (DSIF complex); the complex has multiple roles in
concert with RNA polymerases I and II, including
regulation of transcription elongation, RNA processing,
quality control, and transcription-coupled DNA repair;
Spt4p also localizes to kinetochores and heterochromatin
and affects chromosome dynamics and silencing; required
for transcription through lengthy trinucleotide repeats in
ORFs or non-protein coding regions"
/codon_start=1
/product="Spt4p"
/protein_id="NP_011577.3"
/db_xref="GI:398365457"
/db_xref="SGD:S000003295"
/db_xref="GeneID:852955"
/translation="MSSERACMLCGIVQTTNEFNRDGCPNCQGIFEEAGVSTMECTSP
SFEGLVGMCKPTKSWVAKWLSVDHSIAGMYAIKVDGRLPAEVVELLPHYKPRDGSQVE
"
gene complement(618077..619858)
/gene="VHT1"
/locus_tag="YGR065C"
/db_xref="GeneID:852956"
mRNA complement(618077..619858)
/gene="VHT1"
/locus_tag="YGR065C"
/product="Vht1p"
/transcript_id="NM_001181194.1"
/db_xref="GI:296145099"
/db_xref="GeneID:852956"
CDS complement(618077..619858)
/gene="VHT1"
/locus_tag="YGR065C"
/note="High-affinity plasma membrane H+-biotin (vitamin H)
symporter; mutation results in fatty acid auxotrophy; 12
transmembrane domain containing major facilitator
subfamily member; mRNA levels negatively regulated by iron
deprivation and biotin"
/codon_start=1
/product="Vht1p"
/protein_id="NP_011579.1"
/db_xref="GI:6321502"
/db_xref="SGD:S000003297"
/db_xref="GeneID:852956"
/translation="MTISNKSWRSYFPHLRKLPEDDQYLYSDDTNSSIIAEEELHHSV
DKSSKTDVTAETTAVEPHPHNLRHDLPYEVRDEAGRKWWKYFDEFEYRVNKEYKKSRK
WYEFLYPNHTTQTKAERRLLYKLDIIIALYFFMLCWSKSVDLNNYTNAYVSNMKEDLN
MKGNDYVYTSTIANVGAIVFQLPFMYLLPRFPSHIILPVMDLGWTWFTFACYRANSLA
ELRAYRFILSAFGAAYYPVSQYILGCWYAPDEINSRVCLFFCGQQLGSVTSGLLQSRI
FKSLNGVHGLAGWRWMFLIDAIAISLPTAIIGFFVIPGVPSKCYSLFLTDEEIRIARA
RNKRNQIKDGVDKSKLAPLWSRKLWKKVFCTPAFWVLVVFDTCSWNNMTAYSGSYTLW
LKSNTKYSIAQVNNLSVIPACLGFAYVIFCAFGADLFRCKWIFMVFAAIMNTVSCALL
IKWDIPSKAKWYAFFTTYFSVAASPCLWSFINDFLRFDPQVKAITWIAIYSFSQSTYA
WIPTLAWPTVESPRFKTGYTVSLIFGAIYGLWTFVVLFFYKRNEKKHALGNGIILYDS
NKGEELPEFVKKNMEERDGYYYLKRSS"
gene complement(620921..621799)
/locus_tag="YGR066C"
/db_xref="GeneID:852957"
mRNA complement(620921..621799)
/locus_tag="YGR066C"
/product="hypothetical protein"
/transcript_id="NM_001181195.3"
/db_xref="GI:398365480"
/db_xref="GeneID:852957"
CDS complement(620921..621799)
/locus_tag="YGR066C"
/codon_start=1
/product="hypothetical protein"
/protein_id="NP_011580.3"
/db_xref="GI:398365481"
/db_xref="SGD:S000003298"
/db_xref="GeneID:852957"
/translation="MTSLNIMGRKFILERAKRNDNIEEIYTSAYVSLPSSTDTRLPHF
KAKEEDCDVYEEGTNLVGKNAKYTYRSLGRHLDFLRPGLRFGGSQSSKYTYYTVEVKI
DTVNLPLYKDSRSLDPHVTGTFTIKNLTPVLDKVVTLFEGYVINYNQFPLCSLHWPAE
ETLDPYMAQRESDCSHWKRFGHFGSDNWSLTERNFGQYNHESAEFMNQRYIYLKWKER
FLLDDEEQENLMLDDNHHLEGASFEGFYYVCLDQLTGSVEGYYYHPACELFQKLELVP
TNCDALNTYSSGFEIA"
gene complement(622372..624786)
/locus_tag="YGR067C"
/db_xref="GeneID:852958"
mRNA complement(622372..624786)
/locus_tag="YGR067C"
/product="hypothetical protein"
/transcript_id="NM_001181196.4"
/db_xref="GI:398365494"
/db_xref="GeneID:852958"
CDS complement(622372..624786)
/locus_tag="YGR067C"
/note="hypothetical protein; contains a zinc finger motif
similar to that of Adr1p"
/codon_start=1
/product="hypothetical protein"
/protein_id="NP_011581.4"
/db_xref="GI:398365495"
/db_xref="SGD:S000003299"
/db_xref="GeneID:852958"
/translation="MAAGQKKYICSFCLKPFSRSEHKIRHERSHAGVKPFQCQVCKHS
FVRRDLLQRHIRTVHRTFLLSSYASMTGDKADIPVSLGVGDVDSTSPRDIKMETLVNS
MIKVNSGLINIHYHSSNVEKMDKQQRCVIGKESSSLKKGKSRFKQVKSRLESSISVKI
LQEYSLDFISSRDILTFFRMGVSHLVENKIFQNFFPDLFSSLQNDELVESFWINKPFG
LIIACLGMSISLNQDSQKLWFICCTNLYASSSKHDNDFDTEDILSQTEQHDVFALILF
YSLLVMLENNIPVSNSIKKFDVFSMLQDILKPFTVASSSYHYLNSKENAWFIFDLWVN
ILRDSNNFNNDSLLIFGWFVNQEFISSNPLKDFIYKGPSMSTTDLTLKHINILADSAY
VYFIIKKTYPQELPSDFRVHDLLVYLNECFVMQQPIKPETSANPSLFANVMNARITDC
KSKSNWLLWETIWFEFINNLTLRNGTTRNIWFIDNFPQVSTSCLLHHSSSFVDETLIT
TNLSIISMLLNLKSFTLASLNPRNIQLITDIVSFQLKLFSSELIASSDVSPSQVSQLL
VNPNVHLMLYFWFDTIYVQRQSYLSSTEKEEFEKVEVFVNDYIITHQKNLVTDLHSIL
FDFWSDSFIAYHILLHAIVSSLRDNILYPYLIYSPHLNDQTKALLTDISNWSCFALQQ
PFRKTSRGSLSGASDMKSFSVASCLPLSPNFLKRDSNCNKILLPPLDIKAIEPISTSN
YTYVNSAPKQQEKEQPLLRATGNNINLVQTIVVPPQVNMESQEFSASSTDNKQSKNIE
IFSQIK"
gene complement(625324..627084)
/gene="ART5"
/locus_tag="YGR068C"
/db_xref="GeneID:852960"
mRNA complement(625324..627084)
/gene="ART5"
/locus_tag="YGR068C"
/product="Art5p"
/transcript_id="NM_001181197.1"
/db_xref="GI:296145102"
/db_xref="GeneID:852960"
CDS complement(625324..627084)
/gene="ART5"
/locus_tag="YGR068C"
/note="Protein proposed to regulate the endocytosis of
plasma membrane proteins by recruiting the ubiquitin
ligase Rsp5p to its target in the plasma membrane"
/codon_start=1
/product="Art5p"
/protein_id="NP_011582.1"
/db_xref="GI:6321506"
/db_xref="SGD:S000003300"
/db_xref="GeneID:852960"
/translation="MFSLSSLSSSGGHSEQKERERISYFDIRINSPYKDIILIQGSPL
ELSSIPLSGNLVISVKNEIVVKKISLRLVGRFKLEFLQVGRYKKNSSSLASLVKEKRK
IFECYWDNLLVSSKGDVLVGGENAENQHNSSSGRSTSNQDMDTSGNAIFLSKRSLSSP
VFNKIIRRKTHSSHRKILELPENGVTGTPFEGLRENARSRSSSSNTLNNNSHSYSNRD
GSGSSYLFLMKRGNYELPFNTMLPPEVCETIEGLQSGSILYSFEAIIDGRQLWDTDLS
VHTSPHGPIGSTSTSGNGMRTKNKIIIKKFKYLRILRTLSMDNLAMQEEISVGNTWRD
KLQYETSIPSRAVPIGSTTPVKIKIFPFEKNIRLDRIEMALIQYYAMKDSSAQIYDDE
IAVMKITHLADFGPLTDKLDVDCPFTIPDNLKQITQDCCLQDNLIRVMHKLQVRILLQ
RQVDGEYKNLEIKAQLPMLLFISPHLPMKGRLVLFDKHDGKIHFRPGELVPLFLTTYP
AQGLTPGVELNSTTTAHLALPQPPPNYHESTNDHLMPALQPLGADSVVLTVPSYEQAQ
AQASASSYVTGSVPAYCDDD"
gene 627806..631273
/gene="ROM1"
/locus_tag="YGR070W"
/gene_synonym="SKC1"
/db_xref="GeneID:852961"
mRNA 627806..631273
/gene="ROM1"
/locus_tag="YGR070W"
/gene_synonym="SKC1"
/product="Rom1p"
/transcript_id="NM_001181199.2"
/db_xref="GI:330443565"
/db_xref="GeneID:852961"
CDS 627806..631273
/gene="ROM1"
/locus_tag="YGR070W"
/gene_synonym="SKC1"
/note="GDP/GTP exchange protein (GEP) for Rho1p; mutations
are synthetically lethal with mutations in rom2, which
also encodes a GEP"
/codon_start=1
/product="Rom1p"
/protein_id="NP_011584.2"
/db_xref="GI:330443566"
/db_xref="SGD:S000003302"
/db_xref="GeneID:852961"
/translation="MNSNELDLRNKYFYEIFGKKRKSDTSTPTQLFSGSKVQTNINEI
SITNDEDEDSTEDENKASLKDYTLGHDTGARYRIAPDCSSHQLKASPVLHISTNLNSS
PQSFTGDQISPTNKKISINDSTRQDKGNSCTTTSSPSQKRSNVLLPHVRKHSSPSLLS
FSKNSGSHMGDPNQLSTPPTPKSAGHTMELHSSFNGKHSSSSTSSLFALESLKTQNRR
SSNSSNHSSQYRRHTNQHQRHHSRSKSSPVSLTEISMIKGTPLVYPALLSLIAIKFKQ
TIKLSTHKKMGLLYRDSFTGKQAIDTLCLIIGSLDRNLGMLIGKSLEAQKLFHDVLYD
HGVRDSVLEIYELSSESIFMAHQSQSSTSIANTFSSSSSSVNSLRTKTEIYGVFVPLT
HCYSSTCSLEKLCYSISCPNRLQQQANLHLKLGGGLKRNISLALDKEDDERISWTNSV
PKSVWESLSKQQIKRQEAIYELFTTEKKFVKSLEIIRDTFMKKLLETNIIPSDVRINF
VKHVFAHINEIYSVNREFLKALAQRQSLSPICPGIADIFLQYLPFFDPFLSYIASRPY
AKYLIETQRSVNPNFARFDDEVSNSSLRHGIDSFLSQGVSRPGRYSLLVREIIHFSDP
VTDKDDLQMLMKVQDLLKDLMKRIDRASGAAQDRYDVKVLKQKILFKNEYVNLGLNNE
KRKIKHEGLLSRKDVNKTDASFSGDIQFYLLDNMLLFLKSKAVNKWHQHTVFQRPIPL
PLLFICPAEDMPPIKRYVTENPNCSAGVLLPQYQTSNPKNAIVFAYYGTKQQYQVTLY
APQPAGLQTLIEKVKQEQKRLLDETKHITFKQMVGQFFHSYINTNRVNDVLICHAGKI
LLVATNMGLFVLNYATSINQKPVHLLHKISISQISVLEEYKVMILLIDKKLYGCPLDV
IDDAENADFLFRKNSKVLFKYVAMFKDGFCNGKRIIMIAHHFLHAVQLLIVNPLIFDF
NSGNFKKNLKAGLVDFSVDSEPLSFSFLENKICIGCKKNIKILNVPEVCDKNGFKMRE
LLNLHDNKVLANMYKETFKVVSMFPIKNSTFACFPELCFFLNKQGKREETKGCFHWEG
EPEQFACSYPYIVAINSNFIEIRHIENGELVRCVLGNKIRMLKSYAKKILYCYEDPQG
FEIIELLNF"
gene complement(631481..634063)
/gene="ENV11"
/locus_tag="YGR071C"
/db_xref="GeneID:852962"
mRNA complement(631481..634063)
/gene="ENV11"
/locus_tag="YGR071C"
/product="Env11p"
/transcript_id="NM_001181200.3"
/db_xref="GI:398365510"
/db_xref="GeneID:852962"
CDS complement(631481..634063)
/gene="ENV11"
/locus_tag="YGR071C"
/note="Protein proposed to be involved in vacuolar
functions; mutant shows defect in CPY processing and
fragmented vacuoles; deletion mutant has increased
glycogen accumulation and displays elongated buds; green
fluorescent protein (GFP)-fusion protein localizes to the
nucleus"
/codon_start=1
/product="Env11p"
/protein_id="NP_011585.3"
/db_xref="GI:398365511"
/db_xref="SGD:S000003303"
/db_xref="GeneID:852962"
/translation="MNTALDDLHGDLVTLEDNEIINNSDHSSSHSTSHEEEDEEEDDT
EDIELIEKDGNKILSSRIHPEDEIINDGLNIWIPVQMLKKNIAKFWSHFLAIEKKLTK
VKCKHCGEILTRSDASLTKTFRSHLKTKHNISANKNFYSMNFTVGDSNLKNNTSSTEI
TRRHGYDSLTFNSDQSFKCFDIGKLQSSNYLSISQLVAIVIASENLPLNFFENVSFKS
LLSKFHRIPPLTTNIIEESIIGLSKSIDELIRRSISRNDTQLPFTIHLSDSKESNQPL
YLKYSREIRAQLSNLDLSHLISVNFTELAGKRSLFSLQLFDNTNKVSKGLPLSIFVRK
TTDIDISVWQEQLNNLYSKYPGLQKSVISITLPQSHYTMVLENRNSHNFTFHSGSVRE
IKYHTCIVSELLHCFLQPLFNVPTESMLSSFSVAKENHSGGSLLDSLIDFSHIDLSST
ILGKICCLIEEVNLNDSLKSDFLLYCQNYTQPNCNELTSILSCNCDRFSALKSILEKF
ANLVPFFKSINSHLENESLSESDFRLINTVEETLRTFEQSIEYFASSAPLKFTHTLVF
IIKFELYLTEIIRSFKFTKSKKPFEKILARLLKVKDLYLLDDVNLIGAFLYPSIFQSK
SLLNEIFGTTSVNKIVHNMTKIVLRYLKNFINITNFRSSNSGGESGRNSGNNLLSDYE
AIFMKESRDVELLCNTKLTAPLTEDSLLVQIIRDDLLRYVNRIAHELPNAYHDYLNDN
DISFDGSHFTKHELSEENDSNSGEWCLNPMEETFDIHIPISDSIWNNYISSKNKIEVI
DILLQLLSVNSTSSIRSELSSLTANQDFSTKLSEETIKIKLLNSQFNLEKINFHSGSI
FDAC"
gene 634304..635467
/gene="UPF3"
/locus_tag="YGR072W"
/gene_synonym="SUA6; SUP112"
/db_xref="GeneID:852963"
mRNA 634304..635467
/gene="UPF3"
/locus_tag="YGR072W"
/gene_synonym="SUA6; SUP112"
/product="Upf3p"
/transcript_id="NM_001181201.1"
/db_xref="GI:296145105"
/db_xref="GeneID:852963"
CDS 634304..635467
/gene="UPF3"
/locus_tag="YGR072W"
/gene_synonym="SUA6; SUP112"
/note="Component of the nonsense-mediated mRNA decay (NMD)
pathway, along with Nam7p and Nmd2p; involved in decay of
mRNA containing nonsense codons; involved in telomere
maintenance"
/codon_start=1
/product="Upf3p"
/protein_id="NP_011586.1"
/db_xref="GI:6321509"
/db_xref="SGD:S000003304"
/db_xref="GeneID:852963"
/translation="MSNVAGELKNSEGKKKGRGNRYHNKNRGKSKNETVDPKKNENKV
NNATNATHNNSKGRRNNKKRNREYYNYKRKARLGKSTENEGFKLVIRLLPPNLTADEF
FAILRDNNNDDGDKQDIQGKLKYSDWCFFEGHYSSKVFKNSTYSRCNFLFDNLSDLEK
CANFIKTCKFIDNKDNITIPDMKLSPYVKKFTQTSKKDAALVGTIEEDEIFKTFMNSM
KQLNENDEYSFQDFSVLKSLEKEFSKSIELENKIAERTERVLTELVGTGDKVKNKNKK
KKNKNAKKKFKEEEASAKIPKKKRNRGKKKRENREKSTISKTKNSNVVIIEEAGKEVL
KQRKKKMLLQEKLKISNSSQPQSSSAQTQPSFQPKENLFVPRVKILHRDDTKK"
gene 635712..636152
/gene="SMD1"
/locus_tag="YGR074W"
/gene_synonym="SPP92"
/db_xref="GeneID:852964"
mRNA 635712..636152
/gene="SMD1"
/locus_tag="YGR074W"
/gene_synonym="SPP92"
/product="Smd1p"
/transcript_id="NM_001181203.3"
/db_xref="GI:398365524"
/db_xref="GeneID:852964"
CDS 635712..636152
/gene="SMD1"
/locus_tag="YGR074W"
/gene_synonym="SPP92"
/note="Core Sm protein Sm D1; part of heteroheptameric
complex (with Smb1p, Smd2p, Smd3p, Sme1p, Smx3p, and
Smx2p) that is part of the spliceosomal U1, U2, U4, and U5
snRNPs; homolog of human Sm D1; protein abundance
increases in response to DNA replication stress"
/codon_start=1
/product="Smd1p"
/protein_id="NP_011588.3"
/db_xref="GI:398365525"
/db_xref="SGD:S000003306"
/db_xref="GeneID:852964"
/translation="MKLVNFLKKLRNEQVTIELKNGTTVWGTLQSVSPQMNAILTDVK
LTLPQPRLNKLNSNGIAMASLYLTGGQQPTASDNIASLQYINIRGNTIRQIILPDSLN
LDSLLVDQKQLNSLRRSGQIANDPSKKRRRDFGAPANKRPRRGL"
gene complement(636147..636875)
/gene="PRP38"
/locus_tag="YGR075C"
/db_xref="GeneID:852966"
mRNA complement(636147..636875)
/gene="PRP38"
/locus_tag="YGR075C"
/product="Prp38p"
/transcript_id="NM_001181204.3"
/db_xref="GI:398365532"
/db_xref="GeneID:852966"
CDS complement(636147..636875)
/gene="PRP38"
/locus_tag="YGR075C"
/note="Unique component of the U4/U6.U5 tri-snRNP
particle, required for conformational changes which result
in the catalytic activation of the spliceosome;
dispensible for spliceosome assembly"
/codon_start=1
/product="Prp38p"
/protein_id="NP_011589.3"
/db_xref="GI:398365533"
/db_xref="SGD:S000003307"
/db_xref="GeneID:852966"
/translation="MAVNEFQVESNISPKQLNNQSVSLVIPRLTRDKIHNSMYYKVNL
SNESLRGNTMVELLKVMIGAFGTIKGQNGHLHMMVLGGIEFKCILMKLIEIRPNFQQL
NFLLNVKNENGFDSKYIIALLLVYARLQYYYLNGNNKNDDDENDLIKLFKVQLYKYSQ
HYFKLKSFPLQVDCFAHSYNEELCIIHIDELVDWLATQDHIWGIPLGKCQWNKIYNSD
EESSSSESESNGDSEDDNDTSSES"
gene complement(637104..637577)
/gene="MRPL25"
/locus_tag="YGR076C"
/gene_synonym="AFO1; YMR26"
/db_xref="GeneID:852967"
mRNA complement(637104..637577)
/gene="MRPL25"
/locus_tag="YGR076C"
/gene_synonym="AFO1; YMR26"
/product="mitochondrial 54S ribosomal protein YmL25"
/transcript_id="NM_001181205.1"
/db_xref="GI:296145108"
/db_xref="GeneID:852967"
CDS complement(637104..637577)
/gene="MRPL25"
/locus_tag="YGR076C"
/gene_synonym="AFO1; YMR26"
/note="Mitochondrial ribosomal protein of the large
subunit; mutation confers increased replicative lifespan"
/codon_start=1
/product="mitochondrial 54S ribosomal protein YmL25"
/protein_id="NP_011590.1"
/db_xref="GI:6321513"
/db_xref="SGD:S000003308"
/db_xref="GeneID:852967"
/translation="MSYKQYFDSLPLKLKSFFQRYPPSIKYSPVSTSTKAINANPFLP
NKHPVTQRFHDPKYSLRRMSDVYKLALRYGVEEFLPPIENTKKLFFEEKYNKKTLMKG
VLLPKGHKHELKLNEKLKKREEALKKVDELIASKKGSKYAKRVEKMKKNQSIGWF"
gene complement(637744..639513)
/gene="PEX8"
/locus_tag="YGR077C"
/gene_synonym="PAS6"
/db_xref="GeneID:852968"
mRNA complement(637744..639513)
/gene="PEX8"
/locus_tag="YGR077C"
/gene_synonym="PAS6"
/product="Pex8p"
/transcript_id="NM_001181206.1"
/db_xref="GI:296145109"
/db_xref="GeneID:852968"
CDS complement(637744..639513)
/gene="PEX8"
/locus_tag="YGR077C"
/gene_synonym="PAS6"
/note="Intraperoxisomal organizer of the peroxisomal
import machinery, tightly associated with the lumenal face
of the peroxisomal membrane, essential for peroxisome
biogenesis, binds PTS1-signal receptor Pex5p"
/codon_start=1
/product="Pex8p"
/protein_id="NP_011591.1"
/db_xref="GI:6321514"
/db_xref="SGD:S000003309"
/db_xref="GeneID:852968"
/translation="MFDHDVEYLITALSSETRIQYDQRLLDEIAANVVYYVPRVKSPD
TLYRLVGALFRSQFIVQLPPLRLLHIVKDVFLWKLEVSEPTLPISKFYLVWNAVFESH
RATWNLSQLMVLDGVLVTYPSFKQLNNAYFIDESSNKTALYYRNWKLQLFSPIWAQLW
NTAIVRANLSIQHCLLIALALLFNQSNRSALLHGVDVSWNLVTEKLLDLLEEYVHGIV
QPMEIFSTDSVLSTNLNHLASCLTSSITRSNEATLVNSVRKLERICRYLSDTVASLKE
QQLDFKFQNVFILIILALKELSAMNMTILPNHKDTFYSMICLSLFHVHVLTQKIGTVG
FPSYDYVYDNLVTYFIVMDDLSKITTVLELMKRNNTKQDPNKLVFYINFLNKITNYYG
CRIRLPFITEFIEPLLHFDVFFSGKTGNTLDIEIKESIHTLTITVLSIDSSYSSQVAQ
WQVSRILVYLKMSMDQFIAGKLSANQILLIFGHLSTQLPSLHNYNKHLLRDSLHETYI
RIVNVKNPEKKNVLIECLIVQIAFINNPHHLIGWLNICLQLINTHNKKLLQQLWEMVS
SLESSLAIDWWYTTVLSSQSSKL"
gene complement(639772..640371)
/gene="PAC10"
/locus_tag="YGR078C"
/gene_synonym="GIM2; PFD3; RKS2"
/db_xref="GeneID:852969"
mRNA complement(639772..640371)
/gene="PAC10"
/locus_tag="YGR078C"
/gene_synonym="GIM2; PFD3; RKS2"
/product="Pac10p"
/transcript_id="NM_001181207.3"
/db_xref="GI:398365546"
/db_xref="GeneID:852969"
CDS complement(639772..640371)
/gene="PAC10"
/locus_tag="YGR078C"
/gene_synonym="GIM2; PFD3; RKS2"
/note="Part of the heteromeric co-chaperone GimC/prefoldin
complex, which promotes efficient protein folding"
/codon_start=1
/product="Pac10p"
/protein_id="NP_011592.3"
/db_xref="GI:398365547"
/db_xref="SGD:S000003310"
/db_xref="GeneID:852969"
/translation="MDTLFNSTEKNARGIPQAPFIENVNEIIKDPSDFELCFNKFQER
LSKYKFMQESKLATIKQLKTRIPDLENTLKICQSLRNHSDEGDESDEPILLHYQLNDT
LYTKAQVDIPEDRADLKVGLWLGADVMLEYPIDEAIELLKKKLADSEQSLTVSTEDVE
FLRENITTMEVNCARLYNWDVQRRQDLKQAQEGTKNLKI"
gene 640720..641832
/locus_tag="YGR079W"
/db_xref="GeneID:852970"
mRNA 640720..641832
/locus_tag="YGR079W"
/product="hypothetical protein"
/transcript_id="NM_001181208.1"
/db_xref="GI:296145111"
/db_xref="GeneID:852970"
CDS 640720..641832
/locus_tag="YGR079W"
/note="hypothetical protein; YGR079W is not an essential
gene"
/codon_start=1
/product="hypothetical protein"
/protein_id="NP_011593.1"
/db_xref="GI:6321516"
/db_xref="SGD:S000003311"
/db_xref="GeneID:852970"
/translation="MSSAANEGCVYLFIVVLRLSSFSCVNSFIHSFTRSRTRSSYSLD
ERSLVSYSIVYVAMNKSSKAFQVPNKVITKEDITPLSRSHTKKADTRGTADGKNTTAS
AVEATPIIITTARSIDTAGSLSENATEDDGTQNGDLHDDDDDDDLESTLGYSSEPDPL
FSPCHQPSFTNSTFSYSADNELPMEENHNKNNFHDSSESSIFLPQIQQSFFFGDNSKS
DANNTDFWKEVNGTAEEAICLQETRQRKCSLVALHPGDATTSSNDTLGIEDFIKDDIN
SAEAMEPSPSSSPSSSLLDNLDYNIKLLCYRDNEGKFTLKKRKFLKNSLRSSSAISKK
WKPLSKRDKLLKRAIRRKSGVCQTLSAGFGIGEFML"
gene 642010..643008
/gene="TWF1"
/locus_tag="YGR080W"
/db_xref="GeneID:852971"
mRNA 642010..643008
/gene="TWF1"
/locus_tag="YGR080W"
/product="Twf1p"
/transcript_id="NM_001181209.3"
/db_xref="GI:398365562"
/db_xref="GeneID:852971"
CDS 642010..643008
/gene="TWF1"
/locus_tag="YGR080W"
/note="Twinfilin, highly conserved actin
monomer-sequestering protein involved in regulation of the
cortical actin cytoskeleton, composed of two cofilin-like
regions, localizes actin monomers to sites of rapid
filament assembly"
/codon_start=1
/product="Twf1p"
/protein_id="NP_011594.3"
/db_xref="GI:398365563"
/db_xref="SGD:S000003312"
/db_xref="GeneID:852971"
/translation="MSTQSGIVAEQALLHSLNENLSADGIVIIIAKISPDSTSVHQTQ
VARSFEELVQLASQEREPLYIFYKPEGLDKYFFVSFIPDGSPVRSRMLYASTKNTLAR
QVGSNSLSTEQPLITDAQDLVDLKNFDSARPAGQNKPLTHDEEMQIEINKQQALLRKN
TSVKLVSQDSASPLSLTFRVNSEKPINEILDSEGKNLIIFQIDPSNETIQIVQSDTCP
SVDELYIDLPGPSYTIFRQGDSSFFIYSCPSGSKVKDRMIYASNKNGFINYLKNDQKI
AFSKVVEIGDFVELDKSLLMATNKEDSLDHGSNPDLPNKSNLKFNKPKGPLRKRRT"
gene complement(643148..643780)
/gene="SLX9"
/locus_tag="YGR081C"
/db_xref="GeneID:852972"
mRNA complement(643148..643780)
/gene="SLX9"
/locus_tag="YGR081C"
/product="Slx9p"
/transcript_id="NM_001181210.3"
/db_xref="GI:398365568"
/db_xref="GeneID:852972"
CDS complement(643148..643780)
/gene="SLX9"
/locus_tag="YGR081C"
/note="Protein required for pre-rRNA processing;
associated with the 90S pre-ribosome and 43S small
ribosomal subunit precursor; interacts with U3 snoRNA;
deletion mutant has synthetic fitness defect with an sgs1
deletion mutant"
/codon_start=1
/product="Slx9p"
/protein_id="NP_011595.3"
/db_xref="GI:398365569"
/db_xref="SGD:S000003313"
/db_xref="GeneID:852972"
/translation="MVAKKRNTLRSKVSARNSQNFGPDVANNGILDESYDIESDPRAF
LHQPKETKKEKLLNRQNTFLSNLKGKSTLNDGIAANFDGISKSSIRRRKRKLREELKP
RMQDLLTSLEQEKDLRGIIENSSKDMNNDDDIDMDSKIRFVDTKEMNLKKIEPGSVRI
KKNQPNIRNQKGAKALAANETARFNQVLTNQDFQKNPFGALREVIKLQKQ"
gene 644044..644595
/gene="TOM20"
/locus_tag="YGR082W"
/gene_synonym="MAS20; MOM19"
/db_xref="GeneID:852973"
mRNA 644044..644595
/gene="TOM20"
/locus_tag="YGR082W"
/gene_synonym="MAS20; MOM19"
/product="Tom20p"
/transcript_id="NM_001181211.1"
/db_xref="GI:296145114"
/db_xref="GeneID:852973"
CDS 644044..644595
/gene="TOM20"
/locus_tag="YGR082W"
/gene_synonym="MAS20; MOM19"
/note="Component of the TOM (translocase of outer
membrane) complex responsible for recognition and initial
import steps for all mitochondrially directed proteins;
acts as a receptor for incoming precursor proteins"
/codon_start=1
/product="Tom20p"
/protein_id="NP_011596.1"
/db_xref="GI:6321519"
/db_xref="SGD:S000003314"
/db_xref="GeneID:852973"
/translation="MSQSNPILRGLAITTAIAALSATGYAIYFDYQRRNSPQFRKVLR
QRAKEQAKMEEQAKTHAKEVKLQKVTEFLSMELAKDPIPSDPSEREATFTTNVENGER
LSMQQGKELEAASKFYKALTVYPQPADLLGIYQRSIPEAIYEYIILMIAILPPANVAS
FVKGVVGSKAESDAVAEANDIDD"
gene complement(644860..646815)
/gene="GCD2"
/locus_tag="YGR083C"
/gene_synonym="GCD12"
/db_xref="GeneID:852974"
mRNA complement(644860..646815)
/gene="GCD2"
/locus_tag="YGR083C"
/gene_synonym="GCD12"
/product="Gcd2p"
/transcript_id="NM_001181212.1"
/db_xref="GI:296145115"
/db_xref="GeneID:852974"
CDS complement(644860..646815)
/gene="GCD2"
/locus_tag="YGR083C"
/gene_synonym="GCD12"
/note="Delta subunit of the translation initiation factor
eIF2B, the guanine-nucleotide exchange factor for eIF2;
activity subsequently regulated by phosphorylated eIF2;
first identified as a negative regulator of GCN4
expression"
/codon_start=1
/product="Gcd2p"
/protein_id="NP_011597.1"
/db_xref="GI:6321520"
/db_xref="SGD:S000003315"
/db_xref="GeneID:852974"
/translation="MSESEAKSRSATPPSKAKQATPTTTAAANGEKKLTNKELKELKK
QEKAAKRAAMKQANGISIEQQQQQAQMKKEKKQLQREQQQKREQKQKNANKKKQNERN
VKKSTLFGHLETTEERRATILALTSAVSSPKTSRITAAGLMVPVVASALSGSNVLTAS
SLMPVGPNASSTVSASAPASTTTTLPASSAALSAGTSSASTNTPTAIQQEIASSNASD
VAKTLASISLEAGEFNVIPGISSVIPTVLEQSFDNSSLISSVKELLLNKDLIHPSILL
LTSHLAHYKIVGSIPRCIAMLEVFQIVIKDYQTPKGTTLSRNLTSYLSHQIDLLKKAR
PLSVTMGNAIRWLKQEISLIDPSTPDKAAKKDLCEKIGQFAKEKIELADQLIIDNAST
QIEESTTIVTYGSSKVLTELLLHNAISLKKNIKVIVVDSRPLFEGRKMAETLRNAGVN
VMYALITSLDTIFNMDVDYVFLGAHSILSNGFLYSRAGTAMLAMSAKRRNIPVLVCCE
SLKFSQRVQLDSVTFNELADPNDLVNIDYENPVERRGNKGALLNQFIKERKFEKKKLA
MENKPKGNKIGGKKGSEGESKDASNEEDSNSKNILDGWQELPSLNIVNILYDLTPPEY
IKKVITEFGALPPSSVPVILREYKGSA"
gene complement(647123..648142)
/gene="MRP13"
/locus_tag="YGR084C"
/db_xref="GeneID:852975"
mRNA complement(647123..648142)
/gene="MRP13"
/locus_tag="YGR084C"
/product="mitochondrial 37S ribosomal protein YmS-A"
/transcript_id="NM_001181213.3"
/db_xref="GI:398365580"
/db_xref="GeneID:852975"
CDS complement(647123..648142)
/gene="MRP13"
/locus_tag="YGR084C"
/note="Mitochondrial ribosomal protein of the small
subunit"
/codon_start=1
/product="mitochondrial 37S ribosomal protein YmS-A"
/protein_id="NP_011598.3"
/db_xref="GI:398365581"
/db_xref="SGD:S000003316"
/db_xref="GeneID:852975"
/translation="MGTITVVINEGPILLIRALHRATTNKKMFRSTVWRRFASTGEIA
KAKLDEFLIYHKTDAKLKPFIYRPKNAQILLTKDIRDPKTREPLQPRPPVKPLSKQTL
NDFIYSVEPNSTELLDWFKEWTGTSIRKRAIWTYISPIHVQKMLTASFFKIGKYAHMV
GLLYGIEHKFLKAQNPSVFDIEHFFNTNIMCALHRNRLKDYKDAEIAQRKLQVAWKKV
LNRKNNTGLANILVATLGRQIGFTPELTGLQPVDISLPDIPNSSSGAELKDLLSKYEG
IYLIARTLLDIDQHNAQYLELQEFIRQYQNALSESSDPYDTHLKALGLLETPPPQEST
EKEEK"
gene complement(648383..648907)
/gene="RPL11B"
/locus_tag="YGR085C"
/db_xref="GeneID:852976"
mRNA complement(648383..648907)
/gene="RPL11B"
/locus_tag="YGR085C"
/product="ribosomal 60S subunit protein L11B"
/transcript_id="NM_001181214.1"
/db_xref="GI:296145117"
/db_xref="GeneID:852976"
CDS complement(648383..648907)
/gene="RPL11B"
/locus_tag="YGR085C"
/note="Ribosomal 60S subunit protein L11B; expressed at
half the level of Rpl11Ap; involved in ribosomal assembly;
depletion causes degradation of 60S proteins and RNA;
homologous to mammalian ribosomal protein L11 and
bacterial L5; RPL11B has a paralog, RPL11A, that arose
from the whole genome duplication"
/codon_start=1
/product="ribosomal 60S subunit protein L11B"
/protein_id="NP_011599.1"
/db_xref="GI:6321522"
/db_xref="SGD:S000003317"
/db_xref="GeneID:852976"
/translation="MSTKAQNPMRDLKIEKLVLNISVGESGDRLTRASKVLEQLSGQT
PVQSKARYTVRTFGIRRNEKIAVHVTVRGPKAEEILERGLKVKEYQLRDRNFSATGNF
GFGIDEHIDLGIKYDPSIGIFGMDFYVVMNRPGARVTRRKRCKGTVGNSHKTTKEDTV
SWFKQKYDADVLDK"
gene complement(649598..650617)
/gene="PIL1"
/locus_tag="YGR086C"
/db_xref="GeneID:852977"
mRNA complement(649598..650617)
/gene="PIL1"
/locus_tag="YGR086C"
/product="Pil1p"
/transcript_id="NM_001181215.3"
/db_xref="GI:398365594"
/db_xref="GeneID:852977"
CDS complement(649598..650617)
/gene="PIL1"
/locus_tag="YGR086C"
/note="Primary protein component of eisosomes; eisosomes
are large immobile cell cortex structures associated with
endocytosis; null mutant shows activation of Pkc1p/Ypk1p
stress resistance pathways; detected in phosphorylated
state in mitochondria; member of the BAR domain family;
protein increases in abundance and relocalizes from plasma
membrane to cytoplasm upon DNA replication stress"
/codon_start=1
/product="Pil1p"
/protein_id="NP_011600.3"
/db_xref="GI:398365595"
/db_xref="SGD:S000003318"
/db_xref="GeneID:852977"
/translation="MHRTYSLRNSRAPTASQLQNPPPPPSTTKGRFFGKGGLAYSFRR
SAAGAFGPELSRKLSQLVKIEKNVLRSMELTANERRDAAKQLSIWGLENDDDVSDITD
KLGVLIYEVSELDDQFIDRYDQYRLTLKSIRDIEGSVQPSRDRKDKITDKIAYLKYKD
PQSPKIEVLEQELVRAEAESLVAEAQLSNITRSKLRAAFNYQFDSIIEHSEKIALIAG
YGKALLELLDDSPVTPGETRPAYDGYEASKQIIIDAESALNEWTLDSAQVKPTLSFKQ
DYEDFEPEEGEEEEEEDGQGRWSEDEQEDGQIEEPEQEEEGAVEEHEQVGHQQSESLP
QQTTA"
gene complement(651290..652981)
/gene="PDC6"
/locus_tag="YGR087C"
/db_xref="GeneID:852978"
mRNA complement(651290..652981)
/gene="PDC6"
/locus_tag="YGR087C"
/product="indolepyruvate decarboxylase 6"
/transcript_id="NM_001181216.3"
/db_xref="GI:398365598"
/db_xref="GeneID:852978"
CDS complement(651290..652981)
/gene="PDC6"
/locus_tag="YGR087C"
/EC_number="4.1.1.74"
/EC_number="4.1.1.72"
/EC_number="4.1.1.-"
/EC_number="4.1.1.1"
/note="Minor isoform of pyruvate decarboxylase,
decarboxylates pyruvate to acetaldehyde, involved in amino
acid catabolism; transcription is glucose- and
ethanol-dependent, and is strongly induced during sulfur
limitation"
/codon_start=1
/product="indolepyruvate decarboxylase 6"
/protein_id="NP_011601.3"
/db_xref="GI:398365599"
/db_xref="SGD:S000003319"
/db_xref="GeneID:852978"
/translation="MSEITLGKYLFERLKQVNVNTIFGLPGDFNLSLLDKIYEVDGLR
WAGNANELNAAYAADGYARIKGLSVLVTTFGVGELSALNGIAGSYAEHVGVLHVVGVP
SISAQAKQLLLHHTLGNGDFTVFHRMSANISETTSMITDIATAPSEIDRLIRTTFITQ
RPSYLGLPANLVDLKVPGSLLEKPIDLSLKPNDPEAEKEVIDTVLELIQNSKNPVILS
DACASRHNVKKETQKLIDLTQFPAFVTPLGKGSIDEQHPRYGGVYVGTLSKQDVKQAV
ESADLILSVGALLSDFNTGSFSYSYKTKNVVEFHSDYVKVKNATFLGVQMKFALQNLL
KVIPDVVKGYKSVPVPTKTPANKGVPASTPLKQEWLWNELSKFLQEGDVIISETGTSA
FGINQTIFPKDAYGISQVLWGSIGFTTGATLGAAFAAEEIDPNKRVILFIGDGSLQLT
VQEISTMIRWGLKPYLFVLNNDGYTIEKLIHGPHAEYNEIQTWDHLALLPAFGAKKYE
NHKIATTGEWDALTTDSEFQKNSVIRLIELKLPVFDAPESLIKQAQLTAATNAKQ"
gene 654634..656322
/gene="CTT1"
/locus_tag="YGR088W"
/gene_synonym="SPS101"
/db_xref="GeneID:852979"
mRNA 654634..656322
/gene="CTT1"
/locus_tag="YGR088W"
/gene_synonym="SPS101"
/product="catalase T"
/transcript_id="NM_001181217.1"
/db_xref="GI:296145120"
/db_xref="GeneID:852979"
CDS 654634..656322
/gene="CTT1"
/locus_tag="YGR088W"
/gene_synonym="SPS101"
/EC_number="1.11.1.6"
/note="Cytosolic catalase T, has a role in protection from
oxidative damage by hydrogen peroxide"
/codon_start=1
/product="catalase T"
/protein_id="NP_011602.2"
/db_xref="GI:86559466"
/db_xref="SGD:S000003320"
/db_xref="GeneID:852979"
/translation="MNVFGKKEEKQEKVYSLQNGFPYSHHPYASQYSRPDGPILLQDF
HLLENIASFDRERVPERVVHAKGGGCRLEFELTDSLSDITYAAPYQNVGYKCPGLVRF
STVGGESGTPDTARDPRGVSFKFYTEWGNHDWVFNNTPVFFLRDAIKFPVFIHSQKRD
PQSHLNQFQDTTIYWDYLTLNPESIHQITYMFGDRGTPASWASMNAYSGHSFIMVNKE
GKDTYVQFHVLSDTGFETLTGDKAAELSGSHPDYNQAKLFTQLQNGEKPKFNCYVQTM
TPEQATKFRYSVNDLTKIWPHKEFPLRKFGTITLTENVDNYFQEIEQVAFSPTNTCIP
GIKPSNDSVLQARLFSYPDTQRHRLGANYQQLPVNRPRNLGCPYSKGDSQYTAEQCPF
KAVNFQRDGPMSYYNFGPEPNYISSLPNQTLKFKNEDNDEVSDKFKGIVLDEVTEVSV
RKQEQDQIRNEHIVDAKINQYYYVYGISPLDFEQPRALYEKVYNDEQKKLFVHNVVCH
ACKIKDPKVKKRVTQYFGLLNEDLGKVIAECLGVPWEPVDLEGYAKTWSIASAN"
gene 656960..659770
/gene="NNF2"
/locus_tag="YGR089W"
/db_xref="GeneID:852980"
mRNA 656960..659770
/gene="NNF2"
/locus_tag="YGR089W"
/product="Nnf2p"
/transcript_id="NM_001181218.1"
/db_xref="GI:296145121"
/db_xref="GeneID:852980"
CDS 656960..659770
/gene="NNF2"
/locus_tag="YGR089W"
/note="Protein that exhibits physical and genetic
interactions with Rpb8p, which is a subunit of RNA
polymerases I, II, and III; computational analysis of
large-scale protein-protein interaction data suggests a
role in chromosome segregation"
/codon_start=1
/product="Nnf2p"
/protein_id="NP_011603.1"
/db_xref="GI:6321526"
/db_xref="SGD:S000003321"
/db_xref="GeneID:852980"
/translation="MEEQFTNQKKVSHLQSLMNTKRSEQPTEFAKKHRFKDTLALFLV
FLSFNHFTSLCLLVSFIVATKCKDFLANCFIILFLSKKPSRHIGEVAHIDISTSKVTN
GSSNRKSNSRFFGNSKNSFVIPIPVLICEILFAMLLKIYGGDYFVKPIKNLAISIIAS
FLINDPSDCLSYATSCSVLYAVSTNTFQRVSHFFDIIQLFDMSLRGTGQSIKLFTVFR
KYSQFFKKLFSLFLPMPFKMLGKHSDSMIYYLSFHILFFSFASSLLHPHRQTAENKPL
KKGFNSTKPDVARVQGLQKMRISSSSSVSADSNTLEDQSPMIPNDPGGLSSSNQTIHP
SQQNNSPVPLSSHSNILNPAASYPTDATSSFPYFTSMVKEYKSYQPSVISAEGSNSQA
VTTTTSTTTSPTTFNFSGDNTSLSNEISLSDSSNGNSKKDSDFFSPSNDKYTNQLFEL
NVDFGNMFSSSKLSSDISVTSNLENFIRLLFRRKNQHLIAPLWSMVVTLKTTNFEKKY
LQETSENSLTPTNSNTSYVSNQEKHDKDLDTINTHSVSSRISFTHAGKFKKSVFNNFE
PSNTMALIAKTTSDDYNLLNLVSTNENIFNRNDNDYKVCIIDISTNSITFHIENLHDG
ELIVLVNGVIWSEVSCALILEHVGEEYVVVNGLVPSCSYDIQFINRLNHRDDYLVSDL
IVRTCGNNNAIAGKFENLDFSFPSYYHRKFLSPLLTLKHSVLTTNANLSDERTKLKKT
KKEFSKKLSLLRQEIDYFKGRISQNATHDEKSTLKVENLKVALQQSETAVNKLEMQLK
TLTEKELELEEEYLKKKDLHLKNQLEFSKLEESLSKDLKNSEGRFQKVNQELVQLGSK
LDKLNARNEKLQKEVDQNAEEIEKFSTQFLSKREKDRFRRKEYRIREANKFELTIKGL
EQDINRLENENENIHSLIGNSY"
rep_origin 659809..660053
/note="ARS727;
Autonomously Replicating Sequence"
/db_xref="SGD:S000118463"
gene 661749..661820
/locus_tag="tT(UGU)G1"
/db_xref="GeneID:852981"
tRNA 661749..661820
/locus_tag="tT(UGU)G1"
/product="tRNA-Thr"
/note="Threonine tRNA (tRNA-Thr), predicted by tRNAscan-SE
analysis"
/db_xref="SGD:S000006749"
/db_xref="GeneID:852981"
gene 662358..666071
/gene="UTP22"
/locus_tag="YGR090W"
/db_xref="GeneID:852982"
mRNA 662358..666071
/gene="UTP22"
/locus_tag="YGR090W"
/product="Utp22p"
/transcript_id="NM_001181219.3"
/db_xref="GI:398365616"
/db_xref="GeneID:852982"
CDS 662358..666071
/gene="UTP22"
/locus_tag="YGR090W"
/note="Component of the small-subunit processome; required
for nuclear export of tRNAs; may facilitate binding of
Utp8p to aminoacylated tRNAs and their delivery to Los1p
for export; conserved from yeast to mammals"
/codon_start=1
/product="Utp22p"
/protein_id="NP_011604.3"
/db_xref="GI:398365617"
/db_xref="SGD:S000003322"
/db_xref="GeneID:852982"
/translation="MATSVKRKASETSDQNIVKVQKKHSTQDSTTDNGSKENDHSSQA
INERTVPEQENDESDTSPESNEVATNTAATRHNGKVTATESYDIHIARETAELFKSNI
FKLQIDELLEQVKLKQKHVLKVEKFLHKLYDILQEIPDWEEKSLAEVDSFFKNKIVSV
PFVDPKPIPQNTNYKFNYKKPDISLIGSFALKAGIYQPNGSSIDTLLTMPKELFEKKD
FLNFRCLHKRSVYLAYLTHHLLILLKKDKLDSFLQLEYSYFDNDPLLPILRISCSKPT
GDSLSDYNFYKTRFSINLLIGFPYKVFEPKKLLPNRNCIRIAQESKEQSLPATPLYNF
SVLSSSTHENYLKYLYKTKKQTESFVEATVLGRLWLQQRGFSSNMSHSGSLGGFGTFE
FTILMAALLNGGGINSNKILLHGFSSYQLFKGVIKYLATMDLCHDGHLQFHSNPENSS
SSPASKYIDEGFQTPTLFDKSTKVNILTKMTVSSYQILKEYAGETLRMLNNVVQDQFS
NIFLTNISRFDNLKYDLCYDVQLPLGKYNNLETSLAATFGSMERVKFITLENFLAHKI
TNVARYALGDRIKYIQIEMVGQKSDFPITKRKVYSNTGGNHFNFDFVRVKLIVNPSEC
DKLVTKGPAHSETMSTEAAVFKNFWGIKSSLRRFKDGSITHCCVWSTSSSEPIISSIV
NFALQKHVSKKAQISNETIKKFHNFLPLPNLPSSAKTSVLNLSSFFNLKKSFDDLYKI
IFQMKLPLSVKSILPVGSAFRYTSLCQPVPFAYSDPDFFQDVILEFETSPKWPDEITS
LEKAKTAFLLKIQEELSANSSTYRSFFSRDESIPYNLEIVTLNILTPEGYGFKFRVLT
ERDEILYLRAIANARNELKPELEATFLKFTAKYLASVRHTRTLENISHSYQFYSPVVR
LFKRWLDTHLLLGHITDELAELIAIKPFVDPAPYFIPGSLENGFLKVLKFISQWNWKD
DPLILDLVKPEDDIRDTFETSIGAGSELDSKTMKKLSERLTLAQYKGIQMNFTNLRNS
DPNGTHLQFFVASKNDPSGILYSSGIPLPIATRLTALAKVAVNLLQTHGLNQQTINLL
FTPGLKDYDFVVDLRTPIGLKSSCGILSATEFKNITNDQAPSNFPENLNDLSEKMDPT
YQLVKYLNLKYKNSLILSSRKYIGVNGGEKGDKNVITGLIKPLFKGAHKFRVNLDCNV
KPVDDENVILNKEAIFHEIAAFGNDMVINFETD"
gene 666341..667825
/gene="PRP31"
/locus_tag="YGR091W"
/db_xref="GeneID:852983"
mRNA 666341..667825
/gene="PRP31"
/locus_tag="YGR091W"
/product="Prp31p"
/transcript_id="NM_001181220.1"
/db_xref="GI:296145123"
/db_xref="GeneID:852983"
CDS 666341..667825
/gene="PRP31"
/locus_tag="YGR091W"
/note="Splicing factor, component of the U4/U6-U5 snRNP
complex"
/codon_start=1
/product="Prp31p"
/protein_id="NP_011605.1"
/db_xref="GI:6321528"
/db_xref="SGD:S000003323"
/db_xref="GeneID:852983"
/translation="MSSEEDYFDELEYDLADEVNEEKEDIQTKKLTTVNCQTEKFNPF
EILPESIELFRTLALISPDRLSLSETAQILPKIVDLKRILQQQEIDFIKLLPFFNEII
PLIKSNIKLMHNFLISLYSRRFPELSSLIPSPLQYSKVISILENENYSKNESDELFFH
LENKAKLTREQILVLTMSMKTSFKNKEPLDIKTRTQILEANSILENLWKLQEDIGQYI
ASKISIIAPNVCFLVGPEIAAQLIAHAGGVLEFSRIPSCNIASIGKNKHLSHELHTLE
SGVRQEGYLFASDMIQKFPVSVHKQMLRMLCAKVSLAARVDAGQKNGDRNTVLAHKWK
AELSKKARKLSEAPSISETKALPIPEDQPKKKRAGRKFRKYKEKFRLSHVRQLQNRME
FGKQEQTVLDSYGEEVGLGMSNTSLQQAVGATSGSRRSAGNQAKLTKVMKHRISEANQ
QADEFLISLGHNTEQPNLSPEMVQMHKKQHTNPEEETNWFSGHG"
gene 668189..669907
/gene="DBF2"
/locus_tag="YGR092W"
/db_xref="GeneID:852984"
mRNA 668189..669907
/gene="DBF2"
/locus_tag="YGR092W"
/product="Dbf2p"
/transcript_id="NM_001181221.3"
/db_xref="GI:398365628"
/db_xref="GeneID:852984"
CDS 668189..669907
/gene="DBF2"
/locus_tag="YGR092W"
/EC_number="2.7.11.1"
/note="Ser/Thr kinase involved in transcription and stress
response; functions as part of a network of genes in exit
from mitosis; localization is cell cycle regulated;
activated by Cdc15p during the exit from mitosis; also
plays a role in regulating the stability of SWI5 and CLB2
mRNAs"
/codon_start=1
/product="Dbf2p"
/protein_id="NP_011606.3"
/db_xref="GI:398365629"
/db_xref="SGD:S000003324"
/db_xref="GeneID:852984"
/translation="MLSKSEKNVDLLAGNMSNLSFDGHGTPGGTGLFPNQNITKRRTR
PAGINDSPSPVKPSFFPYEDTSNMDIDEVSQPDMDVSNSPKKLPPKFYERATSNKTQR
VVSVCKMYFLEHYCDMFDYVISRRQRTKQVLEYLQQQSQLPNSDQIKLNEEWSSYLQR
EHQVLRKRRLKPKNRDFEMITQVGQGGYGQVYLARKKDTKEVCALKILNKKLLFKLNE
TKHVLTERDILTTTRSEWLVKLLYAFQDLQSLYLAMEFVPGGDFRTLLINTRCLKSGH
ARFYISEMFCAVNALHDLGYTHRDLKPENFLIDAKGHIKLTDFGLAAGTISNERIESM
KIRLEKIKDLEFPAFTEKSIEDRRKMYNQLREKEINYANSMVGSPDYMALEVLEGKKY
DFTVDYWSLGCMLFESLVGYTPFSGSSTNETYDNLRRWKQTLRRPRQSDGRAAFSDRT
WDLITRLIADPINRLRSFEHVKRMSYFADINFSTLRSMIPPFTPQLDSETDAGYFDDF
TSEADMAKYADVFKRQDKLTAMVDDSAVSSKLVGFTFRHRNGKQGSSGILFNGLEHSD
PFSTFY"
gene 670388..671911
/locus_tag="YGR093W"
/db_xref="GeneID:852985"
mRNA 670388..671911
/locus_tag="YGR093W"
/product="hypothetical protein"
/transcript_id="NM_001181222.3"
/db_xref="GI:398365632"
/db_xref="GeneID:852985"
CDS 670388..671911
/locus_tag="YGR093W"
/note="Putative protein of unconfirmed function; green
fluorescent protein (GFP)-fusion protein localizes to the
nucleus"
/codon_start=1
/product="hypothetical protein"
/protein_id="NP_011607.3"
/db_xref="GI:398365633"
/db_xref="SGD:S000003325"
/db_xref="GeneID:852985"
/translation="MTNAKILVAHISESDADEAIRKIKKVNEKSGPFDLIIIFSNSYD
ENFELNTDGLPQLILLSCDKANNSKSKKINENVTLLHNMGTYKLANGITLSYFIYPDD
TLQGEKKSILDEFGKSEDQVDILLTKEWGLSISERCGRLSGSEVVDELAKKLQARYHF
AFSDEINFYELEPFQWERERLSRFLNIPKYGSGKKWAYAFNMPIGDNELKDEPEPPNL
IANPYNSVVTNSNKRPLETETENSFDGDKQVLANREKNENKKIRTILPSSCHFCFSNP
NLEDHMIISIGKLVYLTTAKGPLSVPKGDMDISGHCLIIPIEHIPKLDPSKNAELTQS
ILAYEASLVKMNYIKFDMCTIVFEIQSERSIHFHKQVIPVPKYLVLKFCSALDRQVHF
NNEKFTRNAKLEFQCYDSHSSKQYVDVINNQSNNYLQFTVYETPEADPKIYLATFNAS
ETIDLQFGRRVLAFLLNLPRRVKWNSSTCLQTKQQETIEAEKFQKAYRTYDISLTEN"
gene 672186..675500
/gene="VAS1"
/locus_tag="YGR094W"
/db_xref="GeneID:852986"
mRNA 672186..675500
/gene="VAS1"
/locus_tag="YGR094W"
/product="valine--tRNA ligase"
/transcript_id="NM_001181223.1"
/db_xref="GI:296145126"
/db_xref="GeneID:852986"
CDS 672186..675500
/gene="VAS1"
/locus_tag="YGR094W"
/EC_number="6.1.1.9"
/note="Mitochondrial and cytoplasmic valyl-tRNA
synthetase"
/codon_start=1
/product="valine--tRNA ligase"
/protein_id="NP_011608.1"
/db_xref="GI:6321531"
/db_xref="SGD:S000003326"
/db_xref="GeneID:852986"
/translation="MNKWLNTLSKTFTFRLLNCHYRRSLPLCQNFSLKKSLTHNQVRF
FKMSDLDNLPPVDPKTGEVIINPLKEDGSPKTPKEIEKEKKKAEKLLKFAAKQAKKNA
AATTGASQKKPKKKKEVEPIPEFIDKTVPGEKKILVSLDDPALKAYNPANVESSWYDW
WIKTGVFEPEFTADGKVKPEGVFCIPAPPPNVTGALHIGHALTIAIQDSLIRYNRMKG
KTVLFLPGFDHAGIATQSVVEKQIWAKDRKTRHDYGREAFVGKVWEWKEEYHSRIKNQ
IQKLGASYDWSREAFTLSPELTKSVEEAFVRLHDEGVIYRASRLVNWSVKLNTAISNL
EVENKDVKSRTLLSVPGYDEKVEFGVLTSFAYPVIGSDEKLIIATTRPETIFGDTAVA
VHPDDDRYKHLHGKFIQHPFLPRKIPIITDKEAVDMEFGTGAVKITPAHDQNDYNTGK
RHNLEFINILTDDGLLNEECGPEWQGMKRFDARKKVIEQLKEKNLYVGQEDNEMTIPT
CSRSGDIIEPLLKPQWWVSQSEMAKDAIKVVRDGQITITPKSSEAEYFHWLGNIQDWC
ISRQLWWGHRCPVYFINIEGEEHDRIDGDYWVAGRSMEEAEKKAAAKYPNSKFTLEQD
EDVLDTWFSSGLWPFSTLGWPEKTKDMETFYPFSMLETGWDILFFWVTRMILLGLKLT
GSVPFKEVFCHSLVRDAQGRKMSKSLGNVIDPLDVITGIKLDDLHAKLLQGNLDPREV
EKAKIGQKESYPNGIPQCGTDAMRFALCAYTTGGRDINLDILRVEGYRKFCNKIYQAT
KFALMRLGDDYQPPATEGLSGNESLVEKWILHKLTETSKIVNEALDKRDFLTSTSSIY
EFWYLICDVYIENSKYLIQEGSAIEKKSAKDTLYILLDNALKLIHPFMPFISEEMWQR
LPKRSTEKAASIVKASYPVYVSEYDDVKSANAYDLVLNITKEARSLLSEYNILKNGKV
FVESNHEEYFKTAEDQKDSIVSLIKAIDEVTVVRDASEIPEGCVLQSVNPEVNVHLLV
KGHVDIDAEIAKVQKKLEKAKKSKNGIEQTINSKDYETKANTQAKEANKSKLDNTVAE
IEGLEATIENLKRLKL"
gene complement(675671..676342)
/gene="RRP46"
/locus_tag="YGR095C"
/db_xref="GeneID:852987"
mRNA complement(675671..676342)
/gene="RRP46"
/locus_tag="YGR095C"
/product="Rrp46p"
/transcript_id="NM_001181224.1"
/db_xref="GI:296145127"
/db_xref="GeneID:852987"
CDS complement(675671..676342)
/gene="RRP46"
/locus_tag="YGR095C"
/EC_number="3.1.13.-"
/note="Exosome non-catalytic core component; involved in
3'-5' RNA processing and degradation in both the nucleus
and the cytoplasm; has similarity to E. coli RNase PH and
to human hRrp46p (EXOSC5)"
/codon_start=1
/product="Rrp46p"
/protein_id="NP_011609.2"
/db_xref="GI:37362654"
/db_xref="SGD:S000003327"
/db_xref="GeneID:852987"
/translation="MSVQAEIGILDHVDGSSEFVSQDTKVICSVTGPIEPKARQELPT
QLALEIIVRPAKGVATTREKVLEDKLRAVLTPLITRHCYPRQLCQITCQILESGEDEA
EFSLRELSCCINAAFLALVDAGIALNSMCASIPIAIIKDTSDIIVDPTAEQLKISLSV
HTLALEFVNGGKVVKNVLLLDSNGDFNEDQLFSLLELGEQKCQELVTNIRRIIQDNIS
PRLVV"
gene 676621..677565
/gene="TPC1"
/locus_tag="YGR096W"
/db_xref="GeneID:852988"
mRNA 676621..677565
/gene="TPC1"
/locus_tag="YGR096W"
/product="Tpc1p"
/transcript_id="NM_001181225.3"
/db_xref="GI:398365650"
/db_xref="GeneID:852988"
CDS 676621..677565
/gene="TPC1"
/locus_tag="YGR096W"
/note="Mitochondrial membrane transporter that mediates
uptake of the essential cofactor thiamine pyrophosphate
(ThPP) into mitochondria; expression appears to be
regulated by carbon source; member of the mitochondrial
carrier family"
/codon_start=1
/product="Tpc1p"
/protein_id="NP_011610.3"
/db_xref="GI:398365651"
/db_xref="SGD:S000003328"
/db_xref="GeneID:852988"
/translation="MFKEEDSLRKGQNVAAWKTLLAGAVSGLLARSITAPMDTIKIRL
QLTPANGLKPFGSQVMEVARSMIKNEGIRSFWKGNIPGSLLYVTYGSAQFSSYSLFNR
YLTPFGLEARLHSLVVGAFAGITSSIVSYPFDVLRTRLVANNQMHSMSITREVRDIWK
LEGLPGFFKGSIASMTTITLTASIMFGTYETIRIYCDENEKTTAAHKKWELATLNHSA
GTIGGVIAKIITFPLETIRRRMQFMNSKHLEKFSRHSSVYGSYKGYGFARIGLQILKQ
EGVSSLYRGILVALSKTIPTTFVSFWGYETAIHYLRMY"
gene 678695..682135
/gene="ASK10"
/locus_tag="YGR097W"
/gene_synonym="RGC2"
/db_xref="GeneID:852989"
mRNA 678695..682135
/gene="ASK10"
/locus_tag="YGR097W"
/gene_synonym="RGC2"
/product="Ask10p"
/transcript_id="NM_001181226.1"
/db_xref="GI:296145129"
/db_xref="GeneID:852989"
CDS 678695..682135
/gene="ASK10"
/locus_tag="YGR097W"
/gene_synonym="RGC2"
/note="Component of RNA polymerase II holoenzyme;
phosphorylated in response to oxidative stress; has a role
in destruction of Ssn8p; proposed to function in
activation of the glycerol channel Fps1p; ASK10 has a
paralog, RGC1, that arose from the whole genome
duplication"
/codon_start=1
/product="Ask10p"
/protein_id="NP_011611.1"
/db_xref="GI:6321534"
/db_xref="SGD:S000003329"
/db_xref="GeneID:852989"
/translation="MSDYFSSRPSQTLTPMGNKPSGGGGGDDASSIHSKSSQYLMDIL
PDSMTLNESVSSIVANNQAKEFILPETDERSPYFINVPIPKAQPTSTTETKKPLAGDE
AIDGQFVKEYPTDILVDRFYKWKKILKGLVIYLREVAYAQEQFARINYQLKGSVKFPF
LTDIDETTNTITDPFTTAPRGPKKAQPAQKKVGLTDSEQFQMQMQQEQQENAVQAPTD
ESKMSLAPHEYKPVQTTESDNTSAASGFVKFGSGSIQDIQVILKKYHLSLANQQFKIS
KEITSTVIPKLEELRKDLRYKITEIKDLHGDFKTNIGAHIQLTSQLLKKYIAAVKFMN
AHGIGNDRASPTNKKPHKLDPKHDPYLLKLQLDLQLKRQVAEETYLQEAFINLQSSGL
QLEKIIYTKIQHALLRYSALIDSEARLMIKNMCQELQHGIISKPPAFEWDNFVTQHPS
CLLNWKSNDPIPPPRKVSDVIYPHMKSPLAKCIKAGYFLKKSELLPTYHQGYFVLTSN
YIHEFQSSDFYNLSSSTPNSTKSSAYSSSVSIADTYANANNAKANNHHRQASDVHNSS
TTTGGTAGANGIRGIRKKSYLAPIMSIPLNDCTLKDASSTKFVLVGKPTLNENADVRK
SSSSTYLSGSSQASLPKYGHETAKIFSKAPFHKFLKGSKPKNKNTKSSELDQFYAAAQ
KESNNYVTWTFKIVSPEPSEEELKHFKRWVQDLKNLTSFNDTKDRIKFIEDRVMKSHR
FKAGHMSRNSVNIGSHTPCLTDSTFTLQDGTTTSVNLKGRAEKPQYIHIQNNSLADFD
GNGFRSKVNTPAIDDYGNLITVERRPAQSPHQYSDYMATSGNTTPSYSSGSRPQSMYN
GYNPAVSITSNGMMLQQSTANNNTNPTTNLRHQRNISQTSSLPGFSYTSLSLPVNSPG
SSNSESSSGGYFAIPLHGNNNNNNYTQRNSEGSSPCYNDDQIRQQQQPLQMQPLSRTS
SSSVNVTAMRSTSAGNSITANAPVVPKVMVNNQNVKTVAADQSATAPSSPTMNSSVTT
INRESPYQTLKKTNSTGNVPCLTAEKTHAHPAFYKRGNNSAQNLTTSSSTASRVHPIR
KHKKNVSFSSLNSLMFSKKGANHGGNLMTNQFMSGGIQEDDGDSTNNDTIKLNQSIYS
"
gene complement(682566..687458)
/gene="ESP1"
/locus_tag="YGR098C"
/db_xref="GeneID:852990"
mRNA complement(682566..687458)
/gene="ESP1"
/locus_tag="YGR098C"
/product="Esp1p"
/transcript_id="NM_001181227.3"
/db_xref="GI:398365660"
/db_xref="GeneID:852990"
CDS complement(682566..687458)
/gene="ESP1"
/locus_tag="YGR098C"
/EC_number="3.4.22.49"
/note="Separase, a caspase-like cysteine protease;
promotes sister chromatid separation by mediating
dissociation of the cohesin Scc1p from chromatin; inhibits
protein phosphatase 2A-Cdc55p to promote mitotic exit;
inhibited by Pds1p; relative distribution to the nucleus
increases upon DNA replication stress"
/codon_start=1
/product="Esp1p"
/protein_id="NP_011612.3"
/db_xref="GI:398365661"
/db_xref="SGD:S000003330"
/db_xref="GeneID:852990"
/translation="MMVKQEEPLNEISPNTPMTSKSYLLNDTLSKVHHSGQTRPLTSV
LSGDASSNSIGILAMHNNIIRDFTKIASNNIDLAIEDITTVDHSLNSIYSLLKSHHMW
GHINSTVKQHLMIIVKLINNNALGLASSEIIFLFNETNLFQAHSLKNILLADFSTWND
YYLSNLKILALQIILKRKLVDEYLPHILELFSHDKRYLLKDPNLKAHALTKIVLSFFS
VTTSCKVLFGLKFLQYIKQFKLPFKKFISNITVECFSKNLLHKNYLEMGPNKIYLNSF
YLSYSMLYDGLDKIMLLDILSYEETTEVQRAIKSKKEFNEYCNMSENRLLWSCISVDD
LNVILENATNFLQNKGKHISATLKCLVCLWSTIRLEGLPKNKDILRQFDCTVIYINSN
IKSINDESAAALLSELLGVLSEICIDYKEPKRLSNIISVLFNASVLFKSHSFLLKTAN
LEISNVLISNDSKTSHRTILKFEKFISSAQSAQKKIEIFSCLFNVYCMLRNDTLSFVF
DFCQNAFIHCFTRLKITKFIEFSNSSEIMLSVLYGNSSIENIPSENWSQLSRMIFCSL
RGIFDLDPLELNNTFDKLHLLNKYELLIRIVYLLNLDMSKHLTTNLSKITKLYINKWL
QKSDEKAERISSFEMDFVKMLLCYLNFNNFDKLSIELSLCIKSKEKYYSSIVPYADNY
LLEAYLSLYMIDDALMMKNQLQKTMNLSTAKIEQALLHASSLINVHLWDSDLTAFQIY
FGKTLPAMKPELFDINNDHNLPMSLYIKVILLNIKIFNESAKLNIKAGNVISAVIDCR
KAQNLALSLLKKKNKLSQGSRLALLKSLSFSFFQLIKIHIRIGSARDCEFYSKELSRI
ISDLEEPIIVYRCLHFLHRYYMITEQTCLQNITLGKANKAFDYLDAEADITSLTMFLY
DNKEFVKLEQSLVLYFGDQLEKTFLPNLWKLHLGKDIDDSICLSEYMPKNVINRVHNM
WQKVMSQLEEDPFFKGMFESTLGIPSSLPVIPSTMPNNILKTPSKHSTGLKLCDSPRS
SSMTPRGKNIRQKFDRIAAISKLKQMKELLESLKLDTLDNHELSKISSLSSLTLTILS
NITSIHNAESSLITNFSLTDLPRHMPLLFDKVLNNIDNKNYREFRVSSLIAPNNISTI
TESIRVSAAQKDLMESNLNINVITIDFCPITGNLLLSKLEPRRKRRTHLRLPLIRSNS
RDLDEVHLSFPEATKKLLSIINESNQTTSVEVTNKIKTREERKSWWTTRYDLDKRMQQ
LLNNIENSWFNGVQGFFSPEVVDNSLFEKFKDKFYEILHQNLPSRKLYGNPAMFIKVE
DWVIELFLKLNPQEIDFLSKMEDLIYFVLDILLFHGEENAYDEIDFSMLHVQLEEQIK
KYRATMTTNSIFHTFLVVSSSCHLFPWECLSFLKDLSITRVPSYVCLNKLLSRFHYQL
PLQVTIEDNISMILNPNGDLSRTESKFKGMFQKIIDAKPSSQLVMNEKPEEETLLKML
QNSNLFVYIGHGGGEQYVRSKEIKKCTKIAPSFLLGCSSAAMKYYGKLEPTGTIYTYL
LGGCPMVLGNLWDVTDKDIDKFSEELFEKMGFRCNTDDLNGNSLSVSYAVSKSRGVCH
LRYLNGAAPVIYGLPIKFVS"
gene 687899..689965
/gene="TEL2"
/locus_tag="YGR099W"
/db_xref="GeneID:852991"
mRNA 687899..689965
/gene="TEL2"
/locus_tag="YGR099W"
/product="Tel2p"
/transcript_id="NM_001181228.3"
/db_xref="GI:398365668"
/db_xref="GeneID:852991"
CDS 687899..689965
/gene="TEL2"
/locus_tag="YGR099W"
/note="Subunit of the ASTRA complex, involved in chromatin
remodeling; subunit of the telomere cap complex
DNA-binding protein specific to single-stranded yeast
telomeric DNA repeats, required for telomere length
regulation and telomere position effect; involved in the
stability or biogenesis of PIKKs such as TORC1"
/codon_start=1
/product="Tel2p"
/protein_id="NP_011613.3"
/db_xref="GI:398365669"
/db_xref="SGD:S000003331"
/db_xref="GeneID:852991"
/translation="MVLETLKQGLDSSQIHEALIQLDSYPREPVDLDASMVLIKFVIP
VYPSLPERSKVILRRLASKSFTFLCQIVTFSRTISGRDGLQEIRIYQEILEDIISFEP
GCLTFYLKASTTSKADRDSIKALFFGSKLFNVLANRIDMAKYLGYLRLQWKFLLESNE
TDPPGFLGEWLVSSFLLNPVLAADMLLGELFLLKESYFFSFQKIISASSLIDQKRLIA
KFLLPYIQVIVTLENLNDVRKILRRFDLDKIISLSVLFEIQSLPLKEVIVRLMSNHSS
TKFVSALVSKFADFTDEEVDTKTCELLVLFAVHNLNHSQREEIAHDERFLNGVTKHLG
SNEREARERAMFIAKLLSGGHLKYESDFKINIPNVKFESNSDDKIIDFQSLKNPSICN
TQTDVGKDKITEVSGHVQSLTLDCSDSDDEDENDEREIVKRIVFLKDLMKEYEKTGES
RKAPLIPLLKQTVKLIRQKADFQLEVGYYAQGILSSIVCLNNEFDEPLFEQWRINALT
SILVVLPEKVNGAINILFNSELSLQQRMSLLSALGLSARELRGLDDPTIVKPKFDFPT
NRLPWDDQSHHNSRLVEVQESTSMIKKTKTVWKSRKLGKDREKGTQNRFRKYAGLFFY
PLAHGWLNGIDVGTYNQLFKSHYLTTLRIIYSCANPVHDFESMTELMNHIISSAIEEG
ISLNKG"
gene 690245..693097
/gene="MDR1"
/locus_tag="YGR100W"
/gene_synonym="GYP2; MIC1"
/db_xref="GeneID:852992"
mRNA 690245..693097
/gene="MDR1"
/locus_tag="YGR100W"
/gene_synonym="GYP2; MIC1"
/product="Mdr1p"
/transcript_id="NM_001181229.1"
/db_xref="GI:296145132"
/db_xref="GeneID:852992"
CDS 690245..693097
/gene="MDR1"
/locus_tag="YGR100W"
/gene_synonym="GYP2; MIC1"
/note="Cytoplasmic GTPase-activating protein for Ypt/Rab
transport GTPases Ypt6p, Ypt31p and Sec4p; involved in
recycling of internalized proteins and regulation of Golgi
secretory function"
/codon_start=1
/product="Mdr1p"
/protein_id="NP_011614.1"
/db_xref="GI:6321537"
/db_xref="SGD:S000003332"
/db_xref="GeneID:852992"
/translation="MSFFDSLRQKAPFLDKLADSFTPTLTRDEKFRLKYKLPANENIL
EDTNAEVSFATSIKDGKGHSDRVNNKGRKTAYVYSGRLFLTPHFLVFRDAFDHSSCVL
ILNISTIKRVERSPSESYEFALLVTLYTGAKVLIQFIGIRYRSEQFCDKLKLNLKENI
PNAKTLPAFLETSYSEFLIAKNILGKKDITVPRAGLGQHFKYPGNPTMVKEKAKLRLW
FDYFRENGRNLAVVQTPMFRKLIRIGVPNRMRGEIWELCSGAMYMRYANSGEYERILN
ENAGKTSQAIDEIEKDLKRSLPEYSAYQTEEGIQRLRNVLTAYSWKNPDVGYCQAMNI
VVAGFLIFMSEEQAFWCLCNLCDIYVPGYYSKTMYGTLLDQRVFESFVEDRMPVLWEY
ILQHDIQLSVVSLPWFLSLFFTSMPLEYAVRIMDIFFMNGSITLFQVALAVLKINADD
ILQADDDGMFIAIIKHYFQTLGQSAHPDSSDIKYRQITKFQELLVTAFKEFSVISEEM
AMHARHKYEKGIFQNIETFMKRTQLRHMPKTFNLSSDDLSNIYDMFYQSIETYKISMG
TGSSNMGFEVFIQFLSKFCDSCRPCEKDKDPAFRKQKRNFLQRLFDNWDSAHIGELTL
NDVVTGLDKLVTVDLLQAINYFFSLYDTDGDGELHREEVLQLSEGLLLLTEPWKSGRY
VDLLTKKRIEDDIAENIIKESGGEIATMNQIELPTGVTIDEEKYKVEQAERYLKAASN
FLQRSFEYAKAVDLAEEVNLIDLSDDEGEEKRTVKQKQLESIKANAALDPTHPKVIDL
PTFRMIILADETYELFFSNTLRSSVHVDEHVNIDNKNKVLRSMFDGILADGKRVAEQV
RRRVDSVATRSSIASVESTPTAAASSITTKEEKYDDLDDFTSEHQPENEELLQSSWFE
IDDANETSTKAIQERSFEPLSANSSEEKSNLIEFEA"
gene 693363..694403
/gene="PCP1"
/locus_tag="YGR101W"
/gene_synonym="MDM37; RBD1"
/db_xref="GeneID:852993"
mRNA 693363..694403
/gene="PCP1"
/locus_tag="YGR101W"
/gene_synonym="MDM37; RBD1"
/product="Pcp1p"
/transcript_id="NM_001181230.1"
/db_xref="GI:296145133"
/db_xref="GeneID:852993"
CDS 693363..694403
/gene="PCP1"
/locus_tag="YGR101W"
/gene_synonym="MDM37; RBD1"
/EC_number="3.4.21.105"
/note="Mitochondrial serine protease required for the
processing of various mitochondrial proteins and
maintenance of mitochondrial DNA and morphology; belongs
to the rhomboid-GlpG superfamily of intramembrane
peptidases"
/codon_start=1
/product="Pcp1p"
/protein_id="NP_011615.1"
/db_xref="GI:6321538"
/db_xref="SGD:S000003333"
/db_xref="GeneID:852993"
/translation="MSGVSSVMLGLRPATRIFFRSNISVSPSRTFVSYIGRSQSTSIL
KNAPNLEDNVTNLQKIIPKRFFSQTSILKSRWKPIFNEETTNRYVRLNRFQQYQQQRS
GGNPLGSMTILGLSLMAGIYFGSPYLFEHVPPFTYFKTHPKNLVYALLGINVAVFGLW
QLPKCWRFLQKYMLLQKDYVTSKISIIGSAFSHQEFWHLGMNMLALWSFGTSLATMLG
ASNFFSLYMNSAIAGSLFSLWYPKLARLAIVGPSLGASGALFGVLGCFSYLFPHAKIL
LFVFPVPGGAWVAFLASVAWNAAGCALRWGSFDYAAHLGGSMMGVLYGWYISKAVEKQ
RQRRLQAAGRWF"
gene complement(694584..695135)
/gene="GTF1"
/locus_tag="YGR102C"
/db_xref="GeneID:852994"
mRNA complement(694584..695135)
/gene="GTF1"
/locus_tag="YGR102C"
/product="glutamyl-tRNA(Gln) amidotransferase subunit F"
/transcript_id="NM_001181231.3"
/db_xref="GI:398365686"
/db_xref="GeneID:852994"
CDS complement(694584..695135)
/gene="GTF1"
/locus_tag="YGR102C"
/note="Subunit of the trimeric GatFAB
AmidoTransferase(AdT) complex; involved in the formation
of Q-tRNAQ; transposon insertion mutant is salt sensitive
and null mutant has growth defects; non-tagged protein is
detected in purified mitochondria"
/codon_start=1
/product="glutamyl-tRNA(Gln) amidotransferase subunit F"
/protein_id="NP_011616.3"
/db_xref="GI:398365687"
/db_xref="SGD:S000003334"
/db_xref="GeneID:852994"
/translation="MYKTWRLCRTHTVGGLCHDGSHRFVSTGGAKIGKKFENMNQIRD
YLSRPVWSVHEYLGINTKEEKLEPPSAEAVKKLLRLSGLPLEGADIKEIQMRLAKQLS
FINKLHNIPVEGEKHTKEYDARLVQRNTKQLNYTKLLEGISHQKQDAELGEVSGSWKA
TGLAAESKNAYFVVKEGLLKNRK"
gene 695417..697234
/gene="NOP7"
/locus_tag="YGR103W"
/gene_synonym="YPH1"
/db_xref="GeneID:852995"
mRNA 695417..697234
/gene="NOP7"
/locus_tag="YGR103W"
/gene_synonym="YPH1"
/product="Nop7p"
/transcript_id="NM_001181232.1"
/db_xref="GI:296145135"
/db_xref="GeneID:852995"
CDS 695417..697234
/gene="NOP7"
/locus_tag="YGR103W"
/gene_synonym="YPH1"
/note="Component of several different pre-ribosomal
particles; forms a complex with Ytm1p and Erb1p that is
required for maturation of the large ribosomal subunit;
required for exit from G0 and the initiation of cell
proliferation"
/codon_start=1
/product="Nop7p"
/protein_id="NP_011617.1"
/db_xref="GI:6321540"
/db_xref="SGD:S000003335"
/db_xref="GeneID:852995"
/translation="MRIKKKNTRGNARNFITRSQAVRKLQVSLADFRRLCIFKGIYPR
EPRNKKKANKGSTAPTTFYYAKDIQYLMHEPVLAKFREHKTFARKLTRALGRGEVSSA
KRLEENRDSYTLDHIIKERYPSFPDAIRDIDDALNMLFLFSNLPSTNQVSSKIINDAQ
KICNQWLAYVAKERLVRKVFVSIKGVYYQANIKGEEVRWLVPFKFPENIPSDVDFRIM
LTFLEFYSTLLHFVLYKLYTDSGLIYPPKLDLKKDKIISGLSSYILESRQEDSLLKLD
PTEIEEDVKVESLDASTLKSALNADEANTDETEKEEEQEKKQEKEQEKEQNEETELDT
FEDNNKNKGDILIQPSKYDSPVASLFSAFVFYVSREVPIDILEFLILSCGGNVISEAA
MDQIENKKDIDMSKVTHQIVDRPVLKNKVAGRTYIQPQWIFDCINKGELVPANKYLPG
EALPPHLSPWGDAIGYDPTAPVEEGEEEESESESESEDQVEEEDQEVVAGEEDDDDDE
ELQAQKELELEAQGIKYSETSEADKDVNKSKNKKRKVDEEEEEKKLKMIMMSNKQKKL
YKKMKYSNAKKEEQAENLKKKKKQIAKQKAKLNKLDSKK"
gene complement(697445..698368)
/gene="SRB5"
/locus_tag="YGR104C"
/gene_synonym="MED18"
/db_xref="GeneID:852996"
mRNA complement(697445..698368)
/gene="SRB5"
/locus_tag="YGR104C"
/gene_synonym="MED18"
/product="Srb5p"
/transcript_id="NM_001181233.3"
/db_xref="GI:398365690"
/db_xref="GeneID:852996"
CDS complement(697445..698368)
/gene="SRB5"
/locus_tag="YGR104C"
/gene_synonym="MED18"
/note="Subunit of the RNA polymerase II mediator complex;
associates with core polymerase subunits to form the RNA
polymerase II holoenzyme; essential for transcriptional
regulation; required for proper termination of
transcription for some genes; involved in telomere
maintenance"
/codon_start=1
/product="Srb5p"
/protein_id="NP_011618.3"
/db_xref="GI:398365691"
/db_xref="SGD:S000003336"
/db_xref="GeneID:852996"
/translation="MVQQLSLFGSIGDDGYDLLISTLTTISGNPPLLYNSLCTVWKPN
PSYDVENVNSRNQLVEPNRIKLSKEVPFSYLIDETMMDKPLNFRILKSFTNDKIPLNY
AMTRNILHNTVPQVTNFNSTNEDQNNSKHTEDTVNESRNSDDIIDVDMDASPAPSNES
CSPWSLQISDIPAAGNNRSVSMQTIAETIILSSAGKNSSVSSLMNGLGYVFEFQYLTI
GVKFFMKHGLILELQKIWQIEEAGNSQITSGGFLLKAYINVSRGTDIDRINYTETALM
NLKKELQGYIELSVPDRQSMDSRVAHGNILI"
gene 698599..698832
/gene="VMA21"
/locus_tag="YGR105W"
/db_xref="GeneID:852997"
mRNA 698599..698832
/gene="VMA21"
/locus_tag="YGR105W"
/product="Vma21p"
/transcript_id="NM_001181234.3"
/db_xref="GI:398365708"
/db_xref="GeneID:852997"
CDS 698599..698832
/gene="VMA21"
/locus_tag="YGR105W"
/note="Integral membrane protein that is required for
vacuolar H+-ATPase (V-ATPase) function, although not an
actual component of the V-ATPase complex; functions in the
assembly of the V-ATPase; localized to the yeast
endoplasmic reticulum (ER)"
/codon_start=1
/product="Vma21p"
/protein_id="NP_011619.3"
/db_xref="GI:398365709"
/db_xref="SGD:S000003337"
/db_xref="GeneID:852997"
/translation="MAVDVPRAVINKLMLFTAAMVVLPVLTFFIIQQFTPNTLISGGL
AAAMANVVLIVYIVVAFREDTEDHKVDGNKKED"
gene complement(698989..699786)
/gene="VOA1"
/locus_tag="YGR106C"
/db_xref="GeneID:852998"
mRNA complement(698989..699786)
/gene="VOA1"
/locus_tag="YGR106C"
/product="Voa1p"
/transcript_id="NM_001181235.1"
/db_xref="GI:296145138"
/db_xref="GeneID:852998"
CDS complement(698989..699786)
/gene="VOA1"
/locus_tag="YGR106C"
/note="Endoplasmic reticulum protein that functions,
together with other assembly factors, in assembly of the
V0 sector of the vacuolar ATPase (V-ATPase); null mutation
enhances the V-ATPase deficiency of a vma21 mutant
impaired in ER retrieval"
/codon_start=1
/product="Voa1p"
/protein_id="NP_011620.1"
/db_xref="GI:6321543"
/db_xref="SGD:S000003338"
/db_xref="GeneID:852998"
/translation="MVFGQLYALFIFTLSCCISKTVQADSSKESSSFISFDKESNWDT
ISTISSTADVISSVDSAIAVFEFDNFSLLDNLMIDEEYPFFNRFFANDVSLTVHDDSP
LNISQSLSPIMEQFTVDELPESASDLLYEYSLDDKSIVLFKFTSDAYDLKKLDEFIDS
CLSFLEDKSGDNLTVVINSLGWAFEDEDGDDEYATEETLSHHDNNKGKEGDDDILSSI
WTEGLLMCLIVSALLLFILIVALSWISNLDITYGALEKSTNPIKKNN"
gene 700675..700756
/locus_tag="tL(GAG)G"
/db_xref="GeneID:852999"
tRNA 700675..700756
/locus_tag="tL(GAG)G"
/product="tRNA-Leu"
/note="Leucine tRNA (tRNA-Leu), predicted by tRNAscan-SE
analysis; not essential for viability even though this is
the only tRNA that decodes GAG codons"
/db_xref="SGD:S000006646"
/db_xref="GeneID:852999"
gene complement(700953..701048)
/locus_tag="tK(UUU)G2"
/db_xref="GeneID:853000"
tRNA complement(join(700953..700988,701012..701048))
/locus_tag="tK(UUU)G2"
/product="tRNA-Lys"
/note="Lysine tRNA (tRNA-Lys), predicted by tRNAscan-SE
analysis; thiolation of uridine at wobble position (34)
requires Ncs6p"
/db_xref="SGD:S000006631"
/db_xref="GeneID:853000"
LTR 701104..701350
/note="Ty1 LTR"
/db_xref="SGD:S000006968"
gene 703636..705051
/gene="CLB1"
/locus_tag="YGR108W"
/gene_synonym="SCB1"
/db_xref="GeneID:853002"
mRNA 703636..705051
/gene="CLB1"
/locus_tag="YGR108W"
/gene_synonym="SCB1"
/product="Clb1p"
/transcript_id="NM_001181237.1"
/db_xref="GI:296145139"
/db_xref="GeneID:853002"
CDS 703636..705051
/gene="CLB1"
/locus_tag="YGR108W"
/gene_synonym="SCB1"
/note="B-type cyclin involved in cell cycle progression;
activates Cdc28p to promote the transition from G2 to M
phase; accumulates during G2 and M, then targeted via a
destruction box motif for ubiquitin-mediated degradation
by the proteasome"
/codon_start=1
/product="Clb1p"
/protein_id="NP_011622.1"
/db_xref="GI:6321545"
/db_xref="SGD:S000003340"
/db_xref="GeneID:853002"
/translation="MSRSLLVENSRTINSNEEKGVNESQYILQKRNVPRTILGNVTNN
ANILQEISMNRKIGMKNFSKLNNFFPLKDDVSRADDFTSSFNDSRQGVKQEVLNNKEN
IPEYGYSEQEKQQCSNDDSFHTNSTALSCNRLIYSENKSISTQMEWQKKIMREDSKKK
RPISTLVEQDDQKKFKLHELTTEEEVLEEYEWDDLDEEDCDDPLMVSEEVNDIFDYLH
HLEIITLPNKANLYKHKNIKQNRDILVNWIIKIHNKFGLLPETLYLAINIMDRFLCEE
VVQLNRLQLVGTSCLFIASKYEEIYSPSIKHFAYETDGACSVEDIKEGERFILEKLDF
QISFANPMNFLRRISKADDYDIQSRTLAKFLMEISIVDFKFIGILPSLCASAAMFLSR
KMLGKGTWDGNLIHYSGGYTKAKLYPVCQLLMDYLVGSTIHDEFLKKYQSRRFLKASI
ISIEWALKVRKNGYDIMTLHE"
gene complement(705359..706501)
/gene="CLB6"
/locus_tag="YGR109C"
/db_xref="GeneID:853003"
mRNA complement(705359..706501)
/gene="CLB6"
/locus_tag="YGR109C"
/product="Clb6p"
/transcript_id="NM_001181238.3"
/db_xref="GI:398365718"
/db_xref="GeneID:853003"
CDS complement(705359..706501)
/gene="CLB6"
/locus_tag="YGR109C"
/note="B-type cyclin involved in DNA replication during S
phase; activates Cdc28p to promote initiation of DNA
synthesis; functions in formation of mitotic spindles
along with Clb3p and Clb4p; most abundant during late G1"
/codon_start=1
/product="Clb6p"
/protein_id="NP_011623.3"
/db_xref="GI:398365719"
/db_xref="SGD:S000003341"
/db_xref="GeneID:853003"
/translation="MNCIPSPISERKIQINNEDCIGKENAFHTIPRESSINLTPHSTN
EKKVLSEVNSNKIDSLQLPRGKLQRDSTHLEKTRKRQLSNDSTDPIEPKTVKKIKCHQ
WKNLDSIEMDDPFMVAEYTDSIFSHLYEKEIQMLPTHNYLMDTQSPYHLKSSMRALLI
DWLVEVHEKFHCLPETLFLAINLLDRFLSQNVVKLNKLQLLCITCLFIACKFEEVKLP
KITNFAYVTDGAATVEGIRKAELFVLSSLGYNISLPNPLNFIRRISKADNYCIETRNM
AKFIMEYSICCNKFIHLKPSYLAAMSMYIARKIKNENSKWDETFIHYSGGIDIESDPA
FKDFISELVEDIAVPDTNLDSLRLKYKKPKHGMVYFKVFDWCKQKR"
gene complement(707108..707179)
/locus_tag="tC(GCA)G"
/db_xref="GeneID:853004"
tRNA complement(707108..707179)
/locus_tag="tC(GCA)G"
/product="tRNA-Cys"
/note="Cysteine tRNA (tRNA-Cys), predicted by tRNAscan-SE
analysis"
/db_xref="SGD:S000006527"
/db_xref="GeneID:853004"
mobile_element 707195..712545
/note="YGRWTy3-1; Ty3 element, LTR retrotransposon of the
Gypsy (Metaviridae) group; contains co-transcribed genes
TYA Gag and TYB Pol, encoding proteins involved in
structure and function of virus-like particles, flanked by
two direct repeats"
/mobile_element_type="retrotransposon:YGRWTy3-1"
/db_xref="SGD:S000006984"
LTR 707195..707534
/note="Ty3 LTR"
/db_xref="SGD:S000006978"
gene 707610..712254
/locus_tag="YGR109W-B"
/db_xref="GeneID:853006"
mRNA join(<707610..708459,708461..>712254)
/locus_tag="YGR109W-B"
/transcript_id="NM_001184381.1"
/db_xref="GI:296145142"
/db_xref="GeneID:853006"
CDS join(707610..708459,708461..712254)
/locus_tag="YGR109W-B"
/EC_number="2.7.7.49"
/EC_number="3.4.23.-"
/EC_number="3.1.26.4"
/EC_number="2.7.7.7"
/ribosomal_slippage
/note="Retrotransposon TYA Gag and TYB Pol genes;
transcribed/translated as one unit; polyprotein is
processed to make a nucleocapsid-like protein (Gag),
reverse transcriptase (RT), protease (PR), and integrase
(IN); similar to retroviral genes"
/codon_start=1
/product="gag-pol fusion protein"
/protein_id="NP_011624.1"
/db_xref="GI:6321547"
/db_xref="SGD:S000007347"
/db_xref="GeneID:853006"
/translation="MSFMDQIPGGGNYPKLPVECLPNFPIQPSLTFRGRNDSHKLKNF
ISEIMLNMSMISWPNDASRIVYCRRHLLNPAAQWANDFVQEQGILEITFDTFIQGLYQ
HFYKPPDINKIFNAITQLSEAKLGIERLNQRFRKIWDRMPPDFMTEKAAIMTYTRLLT
KETYNIVRMHKPETLKDAMEEAYQTTALTERFFPGFELDADGDTIIGATTHLQEEYDS
DYDSEDNLTQNGYVHTVRTRRSYNKPMSNHRNRRNNNPSREECIKNRLCFYCKKEGHR
LNECRARRRVLTDLELESKDQQTPFIKTLPIVHYIAIPEMDNTAEKTIKIQNTKVKTL
FDSGSPTSFIRRDIVELLKYEIYETPPLRFRGFVATKSAVTSEAVTIDLKINDLHITL
AAYILDNMDYQLLIGNPILRRYPKILHTVLNTRESPDSLKPKTYRSETVNNVRTYSAG
NRGNPRNIKLSFAPTILEATDPKSAGNRGDSRTKTLSLATTTPAAIDPLTTLDNPGST
QSTFAQFPIPEEASILEEDGKYSNVVSTIQSVEPNATDHSNKDTFCTLPVWLQQKYRE
IIRNDLPPRPADINNIPVKHDIEIKPGARLPRLQPYHVTEKNEQEINKIVQKLLDNKF
IVPSKSPCSSPVVLVPKKDGTFRLCVDYRTLNKATISDPFPLPRIDNLLSRIGNAQIF
TTLDLHSGYHQIPMEPKDRYKTAFVTPSGKYEYTVMPFGLVNAPSTFARYMADTFRDL
RFVNVYLDDILIFSESPEEHWKHLDTVLERLKNENLIVKKKKCKFASEETEFLGYSIG
IQKIAPLQHKCAAIRDFPTPKTVKQAQRFLGMINYYRRFIPNCSKIAQPIQLFICDKS
QWTEKQDKAIDKLKDALCNSPVLVPFNNKANYRLTTDASKDGIGAVLEEVDNKNKLVG
VVGYFSKSLESAQKNYPAGELELLGIIKALHHFRYMLHGKHFTLRTDHISLLSLQNKN
EPARRVQRWLDDLATYDFTLEYLAGPKNVVADAISRAVYTITPETSRPIDTESWKSYY
KSDPLCSAVLIHMKELTQHNVTPEDMSAFRSYQKKLELSETFRKNYSLEDEMIYYQDR
LVVPIKQQNAVMRLYHDHTLFGGHFGVTVTLAKISPIYYWPKLQHSIIQYIRTCVQCQ
LIKSHRPRLHGLLQPLPIAEGRWLDISMDFVTGLPPTSNNLNMILVVVDRFSKRAHFI
ATRKTLDATQLIDLLFRYIFSYHGFPRTITSDRDVRMTADKYQELTKRLGIKSTMSSA
NHPQTDGQSERTIQTLNRLLRAYASTNIQNWHVYLPQIEFVYNSTPTRTLGKSPFEID
LGYLPNTPAIKSDDEVNARSFTAVELAKHLKALTIQTKEQLEHAQIEMETNNNQRRKP
LLLNIGDHVLVHRDAYFKKGAYMKVQQIYVGPFRVVKKINDNAYELDLNSHKKKHRVI
NVQFLKKFVYRPDAYPKNKPISSTERIKRAHEVTALIGIDTTHKTYLCHMQDVDPTLS
VEYSEAEFCQIPERTRRSILANFRQLYETQDNPEREEDVVSQNEICQYDNTSP"
gene 707610..708482
/locus_tag="YGR109W-A"
/db_xref="GeneID:853005"
mRNA <707610..>708482
/locus_tag="YGR109W-A"
/transcript_id="NM_001184380.3"
/db_xref="GI:398365732"
/db_xref="GeneID:853005"
CDS 707610..708482
/locus_tag="YGR109W-A"
/note="Retrotransposon TYA Gag gene co-transcribed with
TYB Pol; translated as TYA or TYA-TYB polyprotein; Gag is
a nucleocapsid protein that is the structural constituent
of virus-like particles (VLPs); similar to retroviral Gag"
/codon_start=1
/product="gag protein"
/protein_id="NP_058162.3"
/db_xref="GI:398365733"
/db_xref="SGD:S000007346"
/db_xref="GeneID:853005"
/translation="MSFMDQIPGGGNYPKLPVECLPNFPIQPSLTFRGRNDSHKLKNF
ISEIMLNMSMISWPNDASRIVYCRRHLLNPAAQWANDFVQEQGILEITFDTFIQGLYQ
HFYKPPDINKIFNAITQLSEAKLGIERLNQRFRKIWDRMPPDFMTEKAAIMTYTRLLT
KETYNIVRMHKPETLKDAMEEAYQTTALTERFFPGFELDADGDTIIGATTHLQEEYDS
DYDSEDNLTQNGYVHTVRTRRSYNKPMSNHRNRRNNNPSREECIKNRLCFYCKKEGHR
LNECRARKASSNRS"
LTR 712206..712545
/note="Ty3 LTR"
/db_xref="SGD:S000006979"
LTR complement(713084..713384)
/note="Ty1 LTR"
/db_xref="SGD:S000006957"
gene 713709..715046
/gene="CLD1"
/locus_tag="YGR110W"
/db_xref="GeneID:853007"
mRNA 713709..715046
/gene="CLD1"
/locus_tag="YGR110W"
/product="Cld1p"
/transcript_id="NM_001181239.3"
/db_xref="GI:398365738"
/db_xref="GeneID:853007"
CDS 713709..715046
/gene="CLD1"
/locus_tag="YGR110W"
/note="Mitochondrial cardiolipin-specific phospholipase;
functions upstream of Taz1p to generate
monolyso-cardiolipin; transcription increases upon
genotoxic stress; involved in restricting Ty1
transposition; has homology to mammalian CGI-58"
/codon_start=1
/product="Cld1p"
/protein_id="NP_011625.3"
/db_xref="GI:398365739"
/db_xref="SGD:S000003342"
/db_xref="GeneID:853007"
/translation="MFKSTLNSIIRRPLKGFQLLRGADSSNTRPQSPRASARDVTEKQ
ILRTPSAPTAIPLREIIYRVPSLFPRPLEDSVKDFRDFIKNEDAFQTELLKTLPFYPT
PSESKTARLIRTVVDDEGNYINEFCIRPRKTSVPEADLKHLVFIHGYGAGLGFFIKNF
EDIPLLDNEWCIHAIDLPGYGFSSRPKFPFEYPRDNIHSVQDWFHERIHTWFSKRNLL
NRPEKNIVMAHSLGSYLMALYLQKYKESPSFKKLILCSPAGVSYRDFNNTASEVEKWK
PPPWWYVKLWDRNISPFTLVRNFRQLGSKITSGWSYRRFKHILNGDPEQSKRFEALHR
YAYAIFNKRGSGEYLLSFALKCGGEPRLSLEQQLFDGKKSDILKNSNCDWLWLYGDDD
WMDVNGGLRVSRFLKEKLKQKSNVIIVPHSGHHLYLDNYKFFNNILTKEMQKI"
rep_origin 715273..715555
/note="ARS728;
Autonomously Replicating Sequence"
/db_xref="SGD:S000118464"
gene 715828..717030
/locus_tag="YGR111W"
/db_xref="GeneID:853008"
mRNA 715828..717030
/locus_tag="YGR111W"
/product="hypothetical protein"
/transcript_id="NM_001181240.1"
/db_xref="GI:296145144"
/db_xref="GeneID:853008"
CDS 715828..717030
/locus_tag="YGR111W"
/note="hypothetical protein; green fluorescent protein
(GFP)-fusion protein localizes to both the cytoplasm and
the nucleus"
/codon_start=1
/product="hypothetical protein"
/protein_id="NP_011626.1"
/db_xref="GI:6321549"
/db_xref="SGD:S000003343"
/db_xref="GeneID:853008"
/translation="MTASSNDDDLIFECYSDPELKRWTHLANAKAWKGILTVQQYADR
EQLLGSSEISQKNKSNEMMTKYPKSYQWLGQKYFVLKDRSLPDNGKFSQVVSSCETLN
RIGYCIHPGSNGKIEPALIVCIGGVFTFENHRGKGYAKKMIIKLNEFYDKIRDDANTV
LELKNLVINLYSEVGEYYSALGYESMHVPLHRISKLDELTERYCGEDDDHDGKYLGFD
DYRGLVGLHETQFKESLLSLHKENPEKFVFTVAPDFDIFTWFQYRDLFIMNKSGRKAQ
QNLFFGYALSDNSHIIWHHNWNGDSLIIVKIHIPEETFQRKELKLKKLLRKAIEETKL
HGLQELEFWDEEIPIKKYPQLFQLLTELENESKVFSENGSISAVRPPKGYTAEQVIWD
NNTKFCWF"
gene 717358..718527
/gene="SHY1"
/locus_tag="YGR112W"
/db_xref="GeneID:853009"
mRNA 717358..718527
/gene="SHY1"
/locus_tag="YGR112W"
/product="Shy1p"
/transcript_id="NM_001181241.1"
/db_xref="GI:296145145"
/db_xref="GeneID:853009"
CDS 717358..718527
/gene="SHY1"
/locus_tag="YGR112W"
/note="Mitochondrial inner membrane protein required for
assembly of cytochrome c oxidase (complex IV); associates
with complex IV assembly intermediates and complex
III/complex IV supercomplexes; similar to human SURF1
involved in Leigh Syndrome"
/codon_start=1
/product="Shy1p"
/protein_id="NP_011627.1"
/db_xref="GI:6321550"
/db_xref="SGD:S000003344"
/db_xref="GeneID:853009"
/translation="MSLLGARSTYRWFSIAASIPTKNAIGKSTYLLASRNQQYRGIIT
STVDWKPIKTGKSPNDDSRRERSFGKKIVLGLMFAMPIISFYLGTWQVRRLKWKTKLI
AACETKLTYEPIPLPKSFTPDMCEDWEYRKVILTGHFLHNEEMFVGPRKKNGEKGYFL
FTPFIRDDTGEKVLIERGWISEEKVAPDSRNLHHLSLPQEEHLKVVCLVRPPKKRGSL
QWAKKDPNSRLWQVPDIYDMARSSGCTPIQFQALYDMKDHPIIEEHTRNEASQNNSTS
SLWKFWKREPTTAVNGTQAVDNNTSKPRSRQEMPTDQTIEFDERQFIKAGVPIGRKPT
IDLKNNHLQYLVTWYGLSFLSTIFLIVALRKAKRGGVVSQDQLMKEKLKHSRKYM"
gene 718893..719924
/gene="DAM1"
/locus_tag="YGR113W"
/db_xref="GeneID:853010"
mRNA 718893..719924
/gene="DAM1"
/locus_tag="YGR113W"
/product="Dam1p"
/transcript_id="NM_001181242.3"
/db_xref="GI:398365746"
/db_xref="GeneID:853010"
CDS 718893..719924
/gene="DAM1"
/locus_tag="YGR113W"
/note="Essential subunit of the Dam1 complex (aka DASH
complex), couples kinetochores to the force produced by MT
depolymerization thereby aiding in chromosome segregation;
Ipl1p target for regulating kinetochore-MT attachments"
/codon_start=1
/product="Dam1p"
/protein_id="NP_011628.4"
/db_xref="GI:398365747"
/db_xref="SGD:S000003345"
/db_xref="GeneID:853010"
/translation="MSEDKAKLGTTRSATEYRLSIGSAPTSRRSSMGESSSLMKFADQ
EGLTSSVGEYNENTIQQLLLPKIRELSDSIITLDSNFTRLNFIHESLADLNESLGSLL
YGIMSNSWCVEFSQAPHDIQDDLIAIKQLKSLEDEKNNLVMELSNMERGIKRKKDEQG
ENDLAKASQNKQFNQPLFPSSQVRKYRSYDNRDKRKPSKIGNNLQVENEEDYEDDTSS
EASFVLNPTNIGMSKSSQGHVTKTTRLNNNTNSKLRRKSILHTIRNSIASGADLPIEN
DNVVNLGDLHPNNRISLGSGAARVVNGPVTKNRNSMFSGRAERKPTESRHSVAKKTEK
KINTRPPFR"
gene 720409..724764
/gene="SPT6"
/locus_tag="YGR116W"
/gene_synonym="CRE2; SSN20"
/db_xref="GeneID:853011"
mRNA 720409..724764
/gene="SPT6"
/locus_tag="YGR116W"
/gene_synonym="CRE2; SSN20"
/product="Spt6p"
/transcript_id="NM_001181245.1"
/db_xref="GI:296145147"
/db_xref="GeneID:853011"
CDS 720409..724764
/gene="SPT6"
/locus_tag="YGR116W"
/gene_synonym="CRE2; SSN20"
/note="Nucleosome remodeling protein; functions in various
aspects of transcription, chromatin maintenance, and RNA
processing; required for the maintenance of chromatin
structure during transcription in order to inhibit
transcription from promoters within the coding region"
/codon_start=1
/product="Spt6p"
/protein_id="NP_011631.1"
/db_xref="GI:6321552"
/db_xref="SGD:S000003348"
/db_xref="GeneID:853011"
/translation="MEETGDSKLVPRDEEEIVNDNDETKAPSEEEEGEDVFDSSEEDE
DIDEDEDEARKVQEGFIVNDDDENEDPGTSISKKRRKHKRREREEDDRLSEDDLDLLM
ENAGVERTKASSSSGKFKRLKRVGDEGNAAESESDNVAASRQDSTSKLEDFFSEDEEE
EESGLRNGRNNEYGRDEEDHENRNRTADKGGILDELDDFIEDDEFSDEDDETRQRRIQ
EKKLLREQSIKQPTQITGLSSDKIDEMYDIFGDGHDYDWALEIENEELENGNDNNEAE
EEEIDEETGAIKSTKKKISLQDIYDLEDLKKNLMTEGDMKIRKTDIPERYQELRAGIT
DYGNMSSEDQELERNWIAEKISVDKNFDANYDLTEFKEAIGNAIKFITKENLEVPFIY
AYRRNYISSREKDGFLLTEDDLWDIVSLDIEFHSLVNKKDYVQRFYAELHIDDPIVTE
YFKNQNTASIAELNSLQDIYDYLEFKYANEINEMFINHTGKTGKKHLKNSSYEKFKAS
PLYQAVSDIGISAEDVGENISSQHQIHPPVDHPSSKPVEVIESILNANSGDLQVFTSN
TKLAIDTVQKYYSLELSKNTKIREKVRSDFSKYYLADVVLTAKGKKEIQKGSLYEDIK
YAINRTPMHFRRDPDVFLKMVEAESLNLLSVKLHMSSQAQYIEHLFQIALETTNTSDI
AIEWNNFRKLAFNQAMDKIFQDISQEVKDNLTKNCQKLVAKTVRHKFMTKLDQAPFIP
NVRDPKIPKILSLTCGQGRFGADAIIAVYVNRKGDFIRDYKIVDNPFDKTNPEKFEDT
LDNIIQSCQPNAIGINGPNPKTQKFYKRLQEVLHKKQIVDSRGHTIPIIYVEDEVAIR
YQNSERAAQEFPNKPPLVKYCIALARYMHSPLLEYANLTSEEVRSLSIHPHQNLLSSE
QLSWALETAFVDIVNLVSVEVNKATDNNYYASALKYISGFGKRKAIDFLQSLQRLNEP
LLARQQLITHNILHKTIFMNSAGFLYISWNEKRQKYEDLEHDQLDSTRIHPEDYHLAT
KVAADALEYDPDTIAEKEEQGTMSEFIELLREDPDRRAKLESLNLESYAEELEKNTGL
RKLNNLNTIVLELLDGFEELRNDFHPLQGDEIFQSLTGESEKTFFKGSIIPVRVERFW
HNDIICTTNSEVECVVNAQRHAGAQLRRPANEIYEIGKTYPAKVIYIDYANITAEVSL
LDHDVKQQYVPISYSKDPSIWDLKQELEDAEEERKLMMAEARAKRTHRVINHPYYFPF
NGRQAEDYLRSKERGEFVIRQSSRGDDHLVITWKLDKDLFQHIDIQELEKENPLALGK
VLIVDNQKYNDLDQIIVEYLQNKVRLLNEMTSSEKFKSGTKKDVVKFIEDYSRVNPNK
SVYYFSLNHDNPGWFYLMFKINANSKLYTWNVKLTNTGYFLVNYNYPSVIQLCNGFKT
LLKSNSSKNRMNNYR"
gene complement(725049..726479)
/locus_tag="YGR117C"
/db_xref="GeneID:853014"
mRNA complement(725049..726479)
/locus_tag="YGR117C"
/product="hypothetical protein"
/transcript_id="NM_001181246.3"
/db_xref="GI:398365754"
/db_xref="GeneID:853014"
CDS complement(725049..726479)
/locus_tag="YGR117C"
/note="hypothetical protein; green fluorescent protein
(GFP)-fusion protein localizes to the cytoplasm"
/codon_start=1
/product="hypothetical protein"
/protein_id="NP_011632.3"
/db_xref="GI:398365755"
/db_xref="SGD:S000003349"
/db_xref="GeneID:853014"
/translation="MADNSTSRFYTNLLIANYLKHNGLEDTLAAFIRETALPLSALEK
SDSSNSNVGEIPLEDLQSVVEDRIYYKRRSFKDRFKTLSINDDLAPIDNAKYGIQPWN
HSLKFSIDVKLNKSLPKDTLFISATFTEDSKYILLSSATGYLVIYDIEKATSKSFKIN
EKVKSIVKLYGPIGSSGYQYVCPMNGSFYLLNNDFELVNNAVWKIHARMITHIKICNV
TESSWFVITSGMDNFLRLSLLEIKNGNTFLTKLSEIKLASNCTSLNVIANGDGNGQNS
FSVFLTRAEYTHIACYSIIDAKNLVHSYNIALNNAEFSTYAFNIRDVMAVDYVHSNTK
DTIGLSPSTMLVVATSHKPYMRLILVEIPMNTGHPKAMKLDKVQTYYDKILRNFATEI
YQDDFSLPILGKLESSNGVLVGNDEGIYSVDLMTGDSRILNIPGEANSLHDRIKCMDI
SKDQMRMVAGTSTKSIYILNVIRNAQ"
gene 726974..727730
/gene="RPS23A"
/locus_tag="YGR118W"
/db_xref="GeneID:853015"
mRNA join(726974..727038,727358..727730)
/gene="RPS23A"
/locus_tag="YGR118W"
/product="ribosomal 40S subunit protein S23A"
/transcript_id="NM_001181247.3"
/db_xref="GI:398365760"
/db_xref="GeneID:853015"
CDS join(726974..727038,727358..727730)
/gene="RPS23A"
/locus_tag="YGR118W"
/note="Ribosomal protein 28 (rp28) of the small (40S)
ribosomal subunit, required for translational accuracy;
homologous to mammalian ribosomal protein S23 and
bacterial S12; RPS23A has a paralog, RPS23B, that arose
from the whole genome duplication; deletion of both RPS23A
and RPS23B is lethal"
/codon_start=1
/product="ribosomal 40S subunit protein S23A"
/protein_id="NP_011633.3"
/db_xref="GI:398365761"
/db_xref="SGD:S000003350"
/db_xref="GeneID:853015"
/translation="MGKGKPRGLNSARKLRVHRRNNRWAENNYKKRLLGTAFKSSPFG
GSSHAKGIVLEKLGIESKQPNSAIRKCVRVQLIKNGKKVTAFVPNDGCLNFVDENDEV
LLAGFGRKGKAKGDIPGVRFKVVKVSGVSLLALWKEKKEKPRS"
gene complement(728046..729671)
/gene="NUP57"
/locus_tag="YGR119C"
/db_xref="GeneID:853016"
mRNA complement(728046..729671)
/gene="NUP57"
/locus_tag="YGR119C"
/product="Nup57p"
/transcript_id="NM_001181248.1"
/db_xref="GI:296145150"
/db_xref="GeneID:853016"
CDS complement(728046..729671)
/gene="NUP57"
/locus_tag="YGR119C"
/note="FG-nucleoporin component of central core of the
nuclear pore complex (NPC); contributes directly to
nucleocytoplasmic transport and maintenance of the NPC
permeability barrier; found in stable complex with Nic96p
and two other FG-nucleoproteins (Nsp1p and Nup49p)"
/codon_start=1
/product="Nup57p"
/protein_id="NP_011634.1"
/db_xref="GI:6321557"
/db_xref="SGD:S000003351"
/db_xref="GeneID:853016"
/translation="MFGFSGSNNGFGNKPAGSTGFSFGQNNNNTNTQPSASGFGFGGS
QPNSGTATTGGFGANQATNTFGSNQQSSTGGGLFGNKPALGSLGSSSTTASGTTATGT
GLFGQQTAQPQQSTIGGGLFGNKPTTTTGGLFGNSAQNNSTTSGGLFGNKVGSTGSLM
GGNSTQNTSNMNAGGLFGAKPQNTTATTGGLFGSKPQGSTTNGGLFGSGTQNNNTLGG
GGLFGQSQQPQTNTAPGLGNTVSTQPSFAWSKPSTGSNLQQQQQQQIQVPLQQTQAIA
QQQQLSNYPQQIQEQVLKCKESWDPNTTKTKLRAFVYNKVNETEAILYTKPGHVLQEE
WDQAMEKKPSPQTIPIQIYGFEGLNQRNQVQTENVAQARIILNHILEKSTQLQQKHEL
DTASRILKAQSRNVEIEKRILKLGTQLATLKNRGLPLGIAEEKMWSQFQTLLQRSEDP
AGLGKTNELWARLAILKERAKNISSQLDSKLMVFNDDTKNQDSMSKGTGEESNDRINK
IVEILTNQQRGITYLNEVLEKDAAIVKKYKNKT"
gene complement(730033..730821)
/gene="COG2"
/locus_tag="YGR120C"
/gene_synonym="SEC35"
/db_xref="GeneID:853017"
mRNA complement(730033..730821)
/gene="COG2"
/locus_tag="YGR120C"
/gene_synonym="SEC35"
/product="Cog2p"
/transcript_id="NM_001181249.1"
/db_xref="GI:296145151"
/db_xref="GeneID:853017"
CDS complement(730033..730821)
/gene="COG2"
/locus_tag="YGR120C"
/gene_synonym="SEC35"
/note="Essential component of the conserved oligomeric
Golgi complex (Cog1p through Cog8p), a cytosolic tethering
complex that functions in protein trafficking to mediate
fusion of transport vesicles to Golgi compartments"
/codon_start=1
/product="Cog2p"
/protein_id="NP_011635.2"
/db_xref="GI:37362655"
/db_xref="SGD:S000003352"
/db_xref="GeneID:853017"
/translation="MDFLNDDELDLDLPVTAEISKELFATEIEKYRESETNGTDVDNF
DVDRFLVQKNFHYLPLDSLIRDLSGLSQKMVQTLLEQIRSNYDDYLTFSNTYTDEENE
TLINLEKTQSDLQKFMTQLDHLIKDDISNTQEIIKDVLEYLKKLDEIYGSLRNHSQLT
EALSLGKRLSKSLHEMCGIEPLEEEICSGLIEQLYKLITASRRILESCADSNSPYIHH
LRNDYQDLLQEFQISLKILTEKCLENPSSLQNLSLTLVSIIKTA"
gene 731137..731210
/locus_tag="tN(GUU)G"
/db_xref="GeneID:853018"
tRNA 731137..731210
/locus_tag="tN(GUU)G"
/product="tRNA-Asn"
/note="Asparagine tRNA (tRNA-Asn), predicted by
tRNAscan-SE analysis"
/db_xref="SGD:S000006670"
/db_xref="GeneID:853018"
gene complement(731449..732927)
/gene="MEP1"
/locus_tag="YGR121C"
/gene_synonym="AMT1"
/db_xref="GeneID:853019"
mRNA complement(731449..732927)
/gene="MEP1"
/locus_tag="YGR121C"
/gene_synonym="AMT1"
/product="Mep1p"
/transcript_id="NM_001181250.3"
/db_xref="GI:398365770"
/db_xref="GeneID:853019"
CDS complement(731449..732927)
/gene="MEP1"
/locus_tag="YGR121C"
/gene_synonym="AMT1"
/note="Ammonium permease; belongs to a ubiquitous family
of cytoplasmic membrane proteins that transport only
ammonium (NH4+); expression is under the nitrogen
catabolite repression regulation"
/codon_start=1
/product="Mep1p"
/protein_id="NP_011636.3"
/db_xref="GI:398365771"
/db_xref="SGD:S000003353"
/db_xref="GeneID:853019"
/translation="MESRTTGPLTTETYDGPTVAFMILGAALVFFMVPGLGFLYSGLA
RRKSALALIWVVLMATLVGILQWYFWGYSLAFSKSAPNNKFIGNLDSFGFRNVYGKKF
DEDAYPELAYATFQMMFSCVNLSIIAGATAERGRLLPHMVFLFILATIGYCPVTYWIW
SPGGWAYQWGVLDWAGGGNIEILSAVSGFVYSWFLGKRNEKLLINFRPHNVSLVTLGT
SILWFGWLLFNSASSLSPNLRSVYAFMNTCLSAITGGMTWCLLDYRSEKKWSTVGLCS
GIISGLVAATPSSGCITLYGSLIQGIVAGVVCNFATKLKYYAKVDDAMDILAEHGVAG
VIGLIFNALFGADWVIGMDGTTEHEGGWVTHNYKQMYKQIAYIAASIGYTAAVTAIIC
FVLGYIPGMRLRISEEAEEAGMDEDQIGEFAYDYVEVRRDYYLWGVDEDSQRSDVNHR
VNNAHLAAERSSSGTNSSSDGNGEMIQSEKILPIHQEDPANR"
gene 733412..733627
/locus_tag="YGR121W-A"
/db_xref="GeneID:1466458"
mRNA 733412..733627
/locus_tag="YGR121W-A"
/product="hypothetical protein"
/transcript_id="NM_001184551.1"
/db_xref="GI:296145153"
/db_xref="GeneID:1466458"
CDS 733412..733627
/locus_tag="YGR121W-A"
/codon_start=1
/product="hypothetical protein"
/protein_id="NP_878078.1"
/db_xref="GI:33438796"
/db_xref="SGD:S000028550"
/db_xref="GeneID:1466458"
/translation="MSRHKYKLWMCIAKGKRGVGERNTFVPKCSYAPFCASEVLDQLL
RGDNSIVYNFYLKNGSGSVYIGSVFLI"
gene 733935..735143
/locus_tag="YGR122W"
/db_xref="GeneID:853020"
mRNA 733935..735143
/locus_tag="YGR122W"
/product="hypothetical protein"
/transcript_id="NM_001181251.3"
/db_xref="GI:398365776"
/db_xref="GeneID:853020"
CDS 733935..735143
/locus_tag="YGR122W"
/note="Protein that may be involved in pH regulation;
probable ortholog of A. nidulans PalC, which is involved
in pH regulation and binds to the ESCRT-III complex; null
mutant does not properly process Rim101p and has decreased
resistance to rapamycin; GFP-fusion protein is
cytoplasmic; relative distribution to cytoplasm increases
upon DNA replication stress"
/codon_start=1
/product="hypothetical protein"
/protein_id="NP_011637.3"
/db_xref="GI:398365777"
/db_xref="SGD:S000003354"
/db_xref="GeneID:853020"
/translation="MRENAMSTKKLPYKLSGSSKITTSIPNDLIILRNNCINSLNSSS
SKADSITCIDTWLKYTEGLLTHRYEANNDAALIEEEIAIALINVAVFYQDIGIETLYR
AYESSQASNNLWTTSGTYLKRGLGLICFLGKNFQINTANDCQKMQVLNVLNQLSLEFQ
LLQQLGIVVLALSKLRSKISKDAVADLEPQELEELGKSSVFYAKLCIGSYSTASQCQG
GRIVDALFMNYLQSLTYLFLSINQYNNDECGIAIGMLQESIKKLLNIVPNSQLKELDI
LSSTDITKKRDLIKMSFKRKIHGSTLKNQRIFEKKVPFSSKAYMMPLLKSSLDDFVIP
LTILLRYRYQTTNENYSFKTVETDVSKLKELFPRGKSSDIEGTVWSFQDGHLTFADSN
NATHNCGNYF"
LTR 735542..735872
/note="Ty1 LTR"
/db_xref="SGD:S000006969"
LTR 735982..736322
/note="Ty3 LTR"
/db_xref="SGD:S000006980"
gene 736340..736411
/locus_tag="tR(UCU)G3"
/db_xref="GeneID:853022"
tRNA 736340..736411
/locus_tag="tR(UCU)G3"
/product="tRNA-Arg"
/note="Arginine tRNA (tRNA-Arg), predicted by tRNAscan-SE
analysis; one of 11 nuclear tRNA genes containing the
tDNA-anticodon UCU (converted to mcm5-UCU in the mature
tRNA), decodes AGA codons into arginine, one of 19 nuclear
tRNAs for arginine"
/db_xref="SGD:S000006713"
/db_xref="GeneID:853022"
gene complement(736662..738203)
/gene="PPT1"
/locus_tag="YGR123C"
/db_xref="GeneID:853023"
mRNA complement(736662..738203)
/gene="PPT1"
/locus_tag="YGR123C"
/product="Ppt1p"
/transcript_id="NM_001181252.3"
/db_xref="GI:398365780"
/db_xref="GeneID:853023"
CDS complement(736662..738203)
/gene="PPT1"
/locus_tag="YGR123C"
/EC_number="3.1.3.16"
/note="Protein serine/threonine phosphatase, regulates
Hsp90 chaperone by affecting its ATPase and cochaperone
binding activities; has similarity to human phosphatase
PP5; present in both the nucleus and cytoplasm; expressed
during logarithmic growth"
/codon_start=1
/product="Ppt1p"
/protein_id="NP_011639.3"
/db_xref="GI:398365781"
/db_xref="SGD:S000003355"
/db_xref="GeneID:853023"
/translation="MSTPTAADRAKALERKNEGNVFVKEKHFLKAIEKYTEAIDLDST
QSIYFSNRAFAHFKVDNFQSALNDCDEAIKLDPKNIKAYHRRALSCMALLEFKKARKD
LNVLLKAKPNDPAATKALLTCDRFIREERFRKAIGGAENEAKISLCQTLNLSSFDANA
DLANYEGPKLEFEQLYDDKNAFKGAKIKNMSQEFISKMVNDLFLKGKYLPKKYVAAII
SHADTLFRQEPSMVELENNSTPDVKISVCGDTHGQFYDVLNLFRKFGKVGPKHTYLFN
GDFVDRGSWSCEVALLFYCLKILHPNNFFLNRGNHESDNMNKIYGFEDECKYKYSQRI
FNMFAQSFESLPLATLINNDYLVMHGGLPSDPSATLSDFKNIDRFAQPPRDGAFMELL
WADPQEANGMGPSQRGLGHAFGPDITDRFLRNNKLRKIFRSHELRMGGVQFEQKGKLM
TVFSAPNYCDSQGNLGGVIHVVPGHGILQAGRNDDQNLIIETFEAVEHPDIKPMAYSN
GGFGL"
gene 739122..739195
/locus_tag="tI(AAU)G"
/db_xref="GeneID:853024"
tRNA 739122..739195
/locus_tag="tI(AAU)G"
/product="tRNA-Ile"
/note="Isoleucine tRNA (tRNA-Ile), predicted by
tRNAscan-SE analysis"
/db_xref="SGD:S000006604"
/db_xref="GeneID:853024"
gene 739944..741662
/gene="ASN2"
/locus_tag="YGR124W"
/db_xref="GeneID:853025"
mRNA 739944..741662
/gene="ASN2"
/locus_tag="YGR124W"
/product="asparagine synthase (glutamine-hydrolyzing) 2"
/transcript_id="NM_001181253.1"
/db_xref="GI:296145156"
/db_xref="GeneID:853025"
CDS 739944..741662
/gene="ASN2"
/locus_tag="YGR124W"
/EC_number="6.3.5.4"
/note="Asparagine synthetase; catalyzes the synthesis of
L-asparagine from L-aspartate in the asparagine
biosynthetic pathway; ASN2 has a paralog, ASN1, that arose
from the whole genome duplication"
/codon_start=1
/product="asparagine synthase (glutamine-hydrolyzing) 2"
/protein_id="NP_011640.1"
/db_xref="GI:6321563"
/db_xref="SGD:S000003356"
/db_xref="GeneID:853025"
/translation="MCGIFAAFKHEDIHNFKPKALQLSKKIRHRGPDWSGNAVMNSTI
FVHERLAIVGLDSGAQPITSADGEYMLGVNGEIYNHIQLREMCSDYKFQTFSDCEPII
PLYLEHDIDAPKYLDGMFAFCLYDSKKDRIVAARDPIGVVTLYMGRSSQSPETVYFAS
ELKCLTDVCDSIISFPPGHVYDSETDKITRYFTPDWLDEKRIPSTPVDYHAIRHSLEK
AVRKRLMAEVPYGVLLSGGLDSSLIAAIAARETEKANADANEDNNVDEKQLAGIDDQG
HLHTSGWSRLHSFAIGLPNAPDLQAARKVAKFIGSIHHEHTFTLQEGLDALDDVIYHL
ETYDVTTIRASTPMFLLSRKIKAQGVKMVLSGEGSDEIFGGYLYFAQAPSAAEFHTES
VQRVKNLHLADCLRANKSTMAWGLEARVPFLDKDFLQLCMNIDPNEKMIKPKEGRIEK
YILRKAFDTTDEPDVKPYLPEEILWRQKEQFSDGVGYSWIDGLRDTAERAISDAMFAN
PKADWGDDIPTTKEAYWYRLKFDAWFPQKTAADTVMRWIPKADWGCAEDPSGRYAKIH
EKHVSA"
gene 742325..745435
/locus_tag="YGR125W"
/db_xref="GeneID:853026"
mRNA 742325..745435
/locus_tag="YGR125W"
/product="hypothetical protein"
/transcript_id="NM_001181254.1"
/db_xref="GI:296145157"
/db_xref="GeneID:853026"
CDS 742325..745435
/locus_tag="YGR125W"
/note="hypothetical protein; deletion mutant has decreased
rapamycin resistance but normal wormannin resistance;
green fluorescent protein (GFP)-fusion protein localizes
to the vacuole"
/codon_start=1
/product="hypothetical protein"
/protein_id="NP_011641.1"
/db_xref="GI:6321564"
/db_xref="SGD:S000003357"
/db_xref="GeneID:853026"
/translation="MGRTIRRRRSNSSLSEAISVSLGINQDSSVNKMHRASVSAMSPP
LCRSYMSGFFTGGNSPMINNLSDSKLPISNKQHPKVIHGSENLHRQTAQLSNEFCSSS
VEENSPTIKDYMDIIGNGDRKDDQSMRTIEENIDEEYSDEYSRLLLSPASSNVDDDRN
RGLQNSSLPELEDGYAGGYQSLRPSHNLRFRPRNLWHMCTSFPSKFAHYLPAAVLGLL
LNILDALSYGMIIFPITEPVFSHLGPTGISMFYISTIISQAVYSGGWSSFPSGIGSEM
IEITPFYHTMALAIKEALAGNDDEIITTTIFCYVISSMLTGVVFYALGKLRLGKIVGF
FPRHILIGCIGGVGYFLIITGIEVTTRVAKFEYSWPFFSGLFTDYDTLAKWLLPVLLT
VVLIGTQRYFKNSLVLPSFYILTLVLFHFIVAIIPTLSLDALRQAGWIFPIANSDSKW
YDHYRLFNVHKVHWSLVLQQIPTMMALTFFGILHVPINVPALAMSLQMDKYDVDRELI
AHGYSNFFSGLLGSVQNYLVYTNSVLFIRAGADSPFAGFLLIALTICIMIIGPVIISF
IPICIVGSLIFLLGYELLVEALVDTWNKLNRFEYLTVVIIVFTMGIFDFVLGIIVGIL
IACFSFLVDSTKLQTINGEYNGNVARSTVYRDYVQTKFLDGIGEQIYVLKLQNLLFFG
TIISIEEKIERLLQISNKDATKRRIKYLILDFKNINADNIDYSAAEGFNRIKRFTETK
RIKLIISSIKERDRIYNAFNNVGLLNDVELFADLNSALEWCENEFLFQYKQLRKKAKE
RLEEGKQNNVVSAVIAATKNKKIDTIGNGLNRGSNGDTARNLMSLPTNTPRNYQILSV
AQNVFVNDEQAVKNFKKEYKDDEPVLPILLFALKQYRPDIISEVQKVREKEIKFWAQL
CPYFTRRRLASQSHLLHADNIFFLVETGMLKATYELPQGTLYEIFSNGTCFGKIIAPG
NAMPREQKLTIETETDSVLWVIDSSSLNKLKEDNLALYVEVALMVMCIKDTRFKELLG
YTLVSA"
gene 745835..746527
/locus_tag="YGR126W"
/db_xref="GeneID:853027"
mRNA 745835..746527
/locus_tag="YGR126W"
/product="hypothetical protein"
/transcript_id="NM_001181255.3"
/db_xref="GI:398365794"
/db_xref="GeneID:853027"
CDS 745835..746527
/locus_tag="YGR126W"
/note="hypothetical protein; green fluorescent protein
(GFP)-fusion protein localizes to both the cytoplasm and
the nucleus and is induced in response to the DNA-damaging
agent MMS"
/codon_start=1
/product="hypothetical protein"
/protein_id="NP_011642.3"
/db_xref="GI:398365795"
/db_xref="SGD:S000003358"
/db_xref="GeneID:853027"
/translation="MPVPSVTVTTDNEYEDISSFSSIDSYKPEPFTGFKDSEAPEQPL
LKNDTIVGKGQLEDDSNVDDQHRHSDVHSHHSSSTLKRPTSNSIEKMVTHNALEGNSE
TVDSLKEDGLNLNKKALPDITAPVTNSAHDAAFPEEYRLETETGLVKLKTLESLKRED
SRVSSTKKEHINDHTDMHSTRSKVTTNSQGSSLEPNKLNMAVEKNKKRIEKYQKHKSE
KGIKGFFHRIFD"
gene 746798..747736
/locus_tag="YGR127W"
/db_xref="GeneID:853028"
mRNA 746798..747736
/locus_tag="YGR127W"
/product="hypothetical protein"
/transcript_id="NM_001181256.1"
/db_xref="GI:296145159"
/db_xref="GeneID:853028"
CDS 746798..747736
/locus_tag="YGR127W"
/note="hypothetical protein; expression is regulated by
Msn2p/Msn4p, indicating a possible role in stress
response"
/codon_start=1
/product="hypothetical protein"
/protein_id="NP_011643.1"
/db_xref="GI:6321566"
/db_xref="SGD:S000003359"
/db_xref="GeneID:853028"
/translation="MCILMATRAHPDYELILISNRDEFLARKTHATCWHNNDFILSPY
DLAKTSAEKQIFGTWSGINKEGKLATILNLKLDNEQNNTKSRSRGLLPFIFLSIHKAD
FEDWDNYKKFEGHYDGLKSTGDFNFFYGDVIKKQYKVIDSLGRTFDVLSSTCRKDLDS
YMVVSNGKFYDSSSIPGQAWEKVKVARDSLENLVLENIESDEEKIISSCFQLASKSSL
PSTISNPDVLQMVDPNVTMNTIYVPPLRRPPRDDLGASIPDGDYYGTRSQIVLLVSKD
STRVTFIERVLYSSDEDVRKYSVTSPKEEKRFKFKL"
gene complement(747950..750091)
/gene="UTP8"
/locus_tag="YGR128C"
/db_xref="GeneID:853029"
mRNA complement(747950..750091)
/gene="UTP8"
/locus_tag="YGR128C"
/product="Utp8p"
/transcript_id="NM_001181257.3"
/db_xref="GI:398365800"
/db_xref="GeneID:853029"
CDS complement(747950..750091)
/gene="UTP8"
/locus_tag="YGR128C"
/note="Nucleolar protein required for export of tRNAs from
the nucleus; also copurifies with the small subunit (SSU)
processome containing the U3 snoRNA that is involved in
processing of pre-18S rRNA"
/codon_start=1
/product="Utp8p"
/protein_id="NP_011644.3"
/db_xref="GI:398365801"
/db_xref="SGD:S000003360"
/db_xref="GeneID:853029"
/translation="MPSLSQPFRLATLPKIASLSNFSLQADYVQVADGTFNESTNNIT
LGISGSSISQYIINPTPKLTFDYPIPSTNIITACNAEKGQANIDGNIEASTDDEANNE
KTINTQKKRNVEIWAFGLMVNKGNYTLNVITKALEDTTDTSNDHLSESDIDNKAYTGS
DEFLSQYKIKAKAKVMSIKIDTKNSLVIAILQNGLIEIFDFKLTLLHSFDISYDNLKY
AKWFTENGTEYVFVLCPLQDDKVCYKLLELTDCGSGESSPIKELSSTIIEGFSFENSK
LCYQFGKLYKLNQGKIYIYSLPHCQLQQVIEFPMVDKLSPGDDLISFQPVSVNRVLLT
VNNVIYLLDLLHCSTLSQRELTHVKTFQLLKSAVINSEKSHNSKTIAIGISTKNGPNP
TSSLEIINIDVGTNTLKDSLGKSFQVGNNDSSVILKPLFDDKDINDKRVKCNDVSGDS
SVPVLHCNEVIEKLSALQDNDITSFDDIFFKELKIKEEHYTEKDRYISDPGFLNKVLD
LIFGKFSGNDYPKTLTFLLTHPLFPLSRTRNLLSLLRDQPRLFKQAIVTCPNLPLNEL
LEELFSIRNRELLLDISFRILQDFTRDSIKQEMKKLSKLDVQNFIEFITSGGEDSSPE
CFNPSQSTQLFQLLSLVLDSIGLFSLEGALLENLTLYIDKQVEIAERNTELWNLIDTK
GFQHGFASSTFDNGTSQKRALPTYTMEYLDI"
gene 750400..751047
/gene="SYF2"
/locus_tag="YGR129W"
/gene_synonym="NTC31"
/db_xref="GeneID:853030"
mRNA 750400..751047
/gene="SYF2"
/locus_tag="YGR129W"
/gene_synonym="NTC31"
/product="Syf2p"
/transcript_id="NM_001181258.3"
/db_xref="GI:398365802"
/db_xref="GeneID:853030"
CDS 750400..751047
/gene="SYF2"
/locus_tag="YGR129W"
/gene_synonym="NTC31"
/note="Member of the NineTeen Complex (NTC) that contains
Prp19p and stabilizes U6 snRNA in catalytic forms of the
spliceosome containing U2, U5, and U6 snRNAs; isy1 syf2
cells have defective spindles activiating cell cycle
arrest"
/codon_start=1
/product="Syf2p"
/protein_id="NP_011645.3"
/db_xref="GI:398365803"
/db_xref="SGD:S000003361"
/db_xref="GeneID:853030"
/translation="MDFYKLDEKLKELKRKRVDVSIKSRKLADREIQEVSANRKPRVY
SMEDVNDADESVGDTESPEKEKAFHYTVQEYDAWERRHPQGKTGQSQRGGISYDQLAK
LSYEKTLRNLATQTQNSSKQDSSADEEDNKNVPKKGRIGKVQKDTKTGKITIADDDKL
VNKLAVSLQSESKKRYEARKRQMQNAKTLYGVESFINDKNKQFNEKLSRESKGSE"
gene complement(751394..753844)
/locus_tag="YGR130C"
/db_xref="GeneID:853031"
mRNA complement(751394..753844)
/locus_tag="YGR130C"
/product="hypothetical protein"
/transcript_id="NM_001181259.1"
/db_xref="GI:296145162"
/db_xref="GeneID:853031"
CDS complement(751394..753844)
/locus_tag="YGR130C"
/note="Component of the eisosome with unknown function;
GFP-fusion protein localizes to the cytoplasm;
specifically phosphorylated in vitro by mammalian
diphosphoinositol pentakisphosphate (IP7)"
/codon_start=1
/product="hypothetical protein"
/protein_id="NP_011646.1"
/db_xref="GI:6321569"
/db_xref="SGD:S000003362"
/db_xref="GeneID:853031"
/translation="MLFNINRQEDDPFTQLINQSSANTQNQQAHQQESPYQFLQKVVS
NEPKGKEEWVSPFRQDALANRQNNRAYGEDAKNRKFPTVSATSAYSKQQPKDLGYKNI
PKNAKRAKDIRFPTYLTQNEERQYQLLTELELKEKHLKYLKKCQKITDLTKDEKDDTD
TTTSSSTSTSSSSSSSSSSSSSSSSDEGDVTSTTTSEATEATADTATTTTTTTSTSTT
STSTTNAVENSADEATSVEEEHEDKVSESTSIGKGTADSAQINVAEPISSENGVLEPR
TTDQSGGSKSGVVPTDEQKEEKSDVKKVNPPSGEEKKEVEAEGDAEEETEQSSAEESA
ERTSTPETSEPESEEDESPIDPSKAPKVPFQEPSRKERTGIFALWKSPTSSSTQKSKT
AAPSNPVATPENPELIVKTKEHGYLSKAVYDKINYDEKIHQAWLADLRAKEKDKYDAK
NKEYKEKLQDLQNQIDEIENSMKAMREETSEKIEVSKNRLVKKIIDVNAEHNNKKLMI
LKDTENMKNQKLQEKNEVLDKQTNVKSEIDDLNNEKTNVQKEFNDWTTNLSNLSQQLD
AQIFKINQINLKQGKVQNEIDNLEKKKEDLVTQTEENKKLHEKNVQVLESVENKEYLP
QINDIDNQISSLLNEVTIIKQENANEKTQLSAITKRLEDERRAHEEQLKLEAEERKRK
EENLLEKQRQELEEQAHQAQLDHEQQITQVKQTYNDQLTELQDKLATEEKELEAVKRE
RTRLQAEKAIEEQTRQKNADEALKQEILSRQHKQAEGIHAAENHKIPNDRSQKNTSVL
PKDDSLYEYHTEEDVMYA"
gene 754726..755250
/gene="FHN1"
/locus_tag="YGR131W"
/db_xref="GeneID:853032"
mRNA 754726..755250
/gene="FHN1"
/locus_tag="YGR131W"
/product="Fhn1p"
/transcript_id="NM_001181260.1"
/db_xref="GI:296145163"
/db_xref="GeneID:853032"
CDS 754726..755250
/gene="FHN1"
/locus_tag="YGR131W"
/note="hypothetical protein; induced by ketoconazole;
promoter region contains sterol regulatory element motif,
which has been identified as a Upc2p-binding site;
overexpression complements function of Nce102p in NCE102
deletion strain"
/codon_start=1
/product="Fhn1p"
/protein_id="NP_011647.1"
/db_xref="GI:6321570"
/db_xref="SGD:S000003363"
/db_xref="GeneID:853032"
/translation="MLSAADNLVRIINAVFLIISIGLISGLIGTQTKHSSRVNFCMFA
AVYGLVTDSLYGFLANFWTSLTYPAILLVLDFLNFIFTFVAATALAVGIRCHSCKNKT
YLEQNKIIQGSSSRCHQSQAAVAFFYFSCFLFLIKVTVATMGMMQNGGFGSNTGFSRR
RARRQMGIPTISQV"
gene complement(755589..756452)
/gene="PHB1"
/locus_tag="YGR132C"
/db_xref="GeneID:853033"
mRNA complement(755589..756452)
/gene="PHB1"
/locus_tag="YGR132C"
/product="Phb1p"
/transcript_id="NM_001181261.3"
/db_xref="GI:398365814"
/db_xref="GeneID:853033"
CDS complement(755589..756452)
/gene="PHB1"
/locus_tag="YGR132C"
/note="Subunit of the prohibitin complex (Phb1p-Phb2p), a
1.2 MDa ring-shaped inner mitochondrial membrane chaperone
that stabilizes newly synthesized proteins; determinant of
replicative life span; involved in mitochondrial
segregation"
/codon_start=1
/product="Phb1p"
/protein_id="NP_011648.3"
/db_xref="GI:398365815"
/db_xref="SGD:S000003364"
/db_xref="GeneID:853033"
/translation="MSNSAKLIDVITKVALPIGIIASGIQYSMYDVKGGSRGVIFDRI
NGVKQQVVGEGTHFLVPWLQKAIIYDVRTKPKSIATNTGTKDLQMVSLTLRVLHRPEV
LQLPAIYQNLGLDYDERVLPSIGNEVLKSIVAQFDAAELITQREIISQKIRKELSTRA
NEFGIKLEDVSITHMTFGPEFTKAVEQKQIAQQDAERAKFLVEKAEQERQASVIRAEG
EAESAEFISKALAKVGDGLLLIRRLEASKDIAQTLANSSNVVYLPSQHSGGGNSESSG
SPNSLLLNIGR"
gene 756896..757447
/gene="PEX4"
/locus_tag="YGR133W"
/gene_synonym="PAS2; UBC10"
/db_xref="GeneID:853034"
mRNA 756896..757447
/gene="PEX4"
/locus_tag="YGR133W"
/gene_synonym="PAS2; UBC10"
/product="E2 ubiquitin-protein ligase peroxin 4"
/transcript_id="NM_001181262.1"
/db_xref="GI:296145165"
/db_xref="GeneID:853034"
CDS 756896..757447
/gene="PEX4"
/locus_tag="YGR133W"
/gene_synonym="PAS2; UBC10"
/EC_number="6.3.2.19"
/note="Peroxisomal ubiquitin conjugating enzyme required
for peroxisomal matrix protein import and peroxisome
biogenesis"
/codon_start=1
/product="E2 ubiquitin-protein ligase peroxin 4"
/protein_id="NP_011649.1"
/db_xref="GI:6321572"
/db_xref="SGD:S000003365"
/db_xref="GeneID:853034"
/translation="MPNFWILENRRSYTSDTCMSRIVKEYKVILKTLASDDPIANPYR
GIIESLNPIDETDLSKWEAIISGPSDTPYENHQFRILIEVPSSYPMNPPKISFMQNNI
LHCNVKSATGEICLNILKPEEWTPVWDLLHCVHAVWRLLREPVCDSPLDVDIGNIIRC
GDMSAYQGIVKYFLAERERINNH"
gene 757770..761138
/gene="CAF130"
/locus_tag="YGR134W"
/db_xref="GeneID:853035"
mRNA 757770..761138
/gene="CAF130"
/locus_tag="YGR134W"
/product="CCR4-NOT core subunit CAF130"
/transcript_id="NM_001181263.3"
/db_xref="GI:398365826"
/db_xref="GeneID:853035"
CDS 757770..761138
/gene="CAF130"
/locus_tag="YGR134W"
/note="Part of the evolutionarily-conserved CCR4-NOT
transcriptional regulatory complex involved in controlling
mRNA initiation, elongation, and degradation"
/codon_start=1
/product="CCR4-NOT core subunit CAF130"
/protein_id="NP_011650.3"
/db_xref="GI:398365827"
/db_xref="SGD:S000003366"
/db_xref="GeneID:853035"
/translation="MTKKKAATNYAERQNLASEDSSGDSVHFKDFIPLQELLKDKNYV
PSVENLEKILYNETMFNDQKICSNLLLEALIITLFTTISGKSALRLIQTSSLKERKSW
AQSFENNSSSYASIVLSWKDNDILLLKFLRFLLANKTAPLQINRYNLPEYKLPLSFLI
VSKITIPSILLNETYNLLKDYLYSITGRIESLISCSSTFDKPALVVRKILKDYNRMIE
CRNFYFWYSFNAENRVNLTFSDNISLLMENDEGNAGSGLDDSRFDHQKQPREAIMGRT
INDQEQIYSFELNQDGTLEIPNVMEHSLLRHELLFKILNLTTVLTPLLELQFSTLCGL
VDPLMQPTPNDKHIISIDFLFQLFLGLMSQSIKTSQEHNDHYDWKFYMCFNMQKIIDA
TMLRLNCFDFDILNSVNNTDNAVHWKTQLHRWLPHGLNTQDLELLYMIDILAVYTIYK
LYEKIPIQLNPFLFSLISLWKNLSCVILLALEIDRIEEENGTYETPLMVRATIRGAAA
LRSVIATVLNGLVKNNDHDFKHESLNTFMSPYGRKLCHGALYADLRSHTASLLALGAS
IEDVTDLFADLQSGDRFDEDIRYMFDYECEDYDESFSESDHGGLDESVVNPTEKIASG
SNNVFFRRRCNCIFNDDKLVAEDGANEAFGSTNSENVEGAMHNNRNAVHNATTATSDH
VVTSPNPLSVRSRSTFEFDYSGEDWRDVPRDFNMYYSPSYSFIHEPKLDVIFSLTLRG
ATEKLNKEESILLVRSVASCVRNEQDQMILADLESNFSASINGDVEGEGNTKMSKIDN
EDLRRTTPDDIYEIWSEESAFERMLNVNHDVAWRLMDEMLMCTGYRRILIWFLTHLEL
KHSLIYYVFELIMGLRGKPFSGEASDQDKKDDMIYEILKKKQKNEDASGLPFSRQGPI
VLSDIETKMLLQEFFMNAAIFLSSKNNEEENEDGEKISLYSLGLVRLICYMVQTLIAN
DKFFFTKSECTFELQTLLMTWIGILPEAKDLFFKIKTRLAMEEEDSADTMQHEGRKNS
DIEKKLNAKPASELNLKLLNLFPSKPANKDDSSPINTLRSFIADYSFDTQVNPPGRRV
VFYDGKILPLPKADKPIPLHEYITLAELDVGDSE"
gene 761392..762168
/gene="PRE9"
/locus_tag="YGR135W"
/db_xref="GeneID:853036"
mRNA 761392..762168
/gene="PRE9"
/locus_tag="YGR135W"
/product="proteasome core particle subunit alpha 3"
/transcript_id="NM_001181264.3"
/db_xref="GI:398365830"
/db_xref="GeneID:853036"
CDS 761392..762168
/gene="PRE9"
/locus_tag="YGR135W"
/EC_number="3.4.25.1"
/note="Alpha 3 subunit of the 20S proteasome, the only
nonessential 20S subunit; may be replaced by the alpha 4
subunit (Pre6p) under stress conditions to create a more
active proteasomal isoform"
/codon_start=1
/product="proteasome core particle subunit alpha 3"
/protein_id="NP_011651.3"
/db_xref="GI:398365831"
/db_xref="SGD:S000003367"
/db_xref="GeneID:853036"
/translation="MGSRRYDSRTTIFSPEGRLYQVEYALESISHAGTAIGIMASDGI
VLAAERKVTSTLLEQDTSTEKLYKLNDKIAVAVAGLTADAEILINTARIHAQNYLKTY
NEDIPVEILVRRLSDIKQGYTQHGGLRPFGVSFIYAGYDDRYGYQLYTSNPSGNYTGW
KAISVGANTSAAQTLLQMDYKDDMKVDDAIELALKTLSKTTDSSALTYDRLEFATIRK
GANDGEVYQKIFKPQEIKDILVKTGITKKDEDEEADEDMK"
gene 762428..763153
/gene="LSB1"
/locus_tag="YGR136W"
/db_xref="GeneID:853037"
mRNA 762428..763153
/gene="LSB1"
/locus_tag="YGR136W"
/product="Lsb1p"
/transcript_id="NM_001181265.1"
/db_xref="GI:296145168"
/db_xref="GeneID:853037"
CDS 762428..763153
/gene="LSB1"
/locus_tag="YGR136W"
/note="Protein containing an N-terminal SH3 domain; binds
Las17p, which is a homolog of human Wiskott-Aldrich
Syndrome protein involved in actin patch assembly and
actin polymerization; protein increases in abundance and
forms nuclear foci in response to DNA replication stress"
/codon_start=1
/product="Lsb1p"
/protein_id="NP_011652.1"
/db_xref="GI:6321575"
/db_xref="SGD:S000003368"
/db_xref="GeneID:853037"
/translation="MSASLVNRSLKNIRNELEFLKESNVISGDIFELINSKLPEKWDG
NQRSPQNADTEEYVEALYDFEAQQDGDLSLKTGDKIQVLEKISPDWYRGKSNNKIGIF
PANYVKPAFTRSASPKSAEAASSSTVSRPSVPPPSYEPAASQYPSQQVSAPYAPPAGY
MQAPPPQQQQAPLPYPPPFTNYYQQPQQQYAPPSQQAPVEAQPQQSSGASSAFKSFGS
KLGNAAIFGAGSAIGSDIVNSIF"
gene complement(763762..765606)
/gene="TPO2"
/locus_tag="YGR138C"
/db_xref="GeneID:853039"
mRNA complement(763762..765606)
/gene="TPO2"
/locus_tag="YGR138C"
/product="Tpo2p"
/transcript_id="NM_001181267.1"
/db_xref="GI:296145169"
/db_xref="GeneID:853039"
CDS complement(763762..765606)
/gene="TPO2"
/locus_tag="YGR138C"
/note="Polyamine transporter of the major facilitator
superfamily; member of the 12-spanner drug:H(+) antiporter
DHA1 family; specific for spermine; localizes to the
plasma membrane; transcription of TPO2 is regulated by
Haa1p; TPO2 has a paralog, TPO3, that arose from the whole
genome duplication"
/codon_start=1
/product="Tpo2p"
/protein_id="NP_011654.1"
/db_xref="GI:6321577"
/db_xref="SGD:S000003370"
/db_xref="GeneID:853039"
/translation="MSDQESVVSFNSQNTSMVDVEGQQPQQYVPSKTNSRANQLKLTK
TETVKSLQDLGVTSAAPVPDINAPQTAKNNIFPEEYTMETPSGLVPVATLQSMGRTAS
ALSRTRTKQLNRTATNSSSTGKEEMEEEETEEREDQSGENELDPEIEFVTFVTGDPEN
PHNWPSWVRWSYTVLLSILVICVAYGSACISGGLGTVEKKYHVGMEAAILSCSLMVIG
FSLGPLIWSPVSDLYGRRVAYFVSMGLYVIFNIPCALAPNLGCLLACRFLCGVWSSSG
LCLVGGSIADMFPSETRGKAIAFFAFAPYVGPVVGPLVNGFISVSTGRMDLIFWVNMA
FAGVMWIISSAIPETYAPVILKRKAARLRKETGNPKIMTEQEAQGVSMSEMMRACLLR
PLYFAVTEPVLVATCFYVCLIYSLLYAFFFAFPVIFGELYGYKDNLVGLMFIPIVIGA
LWALATTFYCENKYLQIVKQRKPTPEDRLLGAKIGAPFAAIALWILGATAYKHIIWVG
PASAGLAFGFGMVLIYYSLNNYIIDCYVQYASSALATKVFLRSAGGAAFPLFTIQMYH
KLNLHWGSWLLAFISTAMIALPFAFSYWGKGLRHKLSKKDYSIDSVEM"
gene 767429..770299
/gene="CBF2"
/locus_tag="YGR140W"
/gene_synonym="CEP2; CSL5; CTF14; NDC10"
/db_xref="GeneID:853041"
mRNA 767429..770299
/gene="CBF2"
/locus_tag="YGR140W"
/gene_synonym="CEP2; CSL5; CTF14; NDC10"
/product="Cbf2p"
/transcript_id="NM_001181269.3"
/db_xref="GI:398365850"
/db_xref="GeneID:853041"
CDS 767429..770299
/gene="CBF2"
/locus_tag="YGR140W"
/gene_synonym="CEP2; CSL5; CTF14; NDC10"
/note="Essential kinetochore protein; component of the
CBF3 multisubunit complex that binds to the CDEIII region
of the centromere; Cbf2p also binds to the CDEII region
possibly forming a different multimeric complex,
ubiquitinated in vivo; relative distribution to the
spindle pole body decreases upon DNA replication stress"
/codon_start=1
/product="Cbf2p"
/protein_id="NP_011656.3"
/db_xref="GI:398365851"
/db_xref="SGD:S000003372"
/db_xref="GeneID:853041"
/translation="MRSSILFLLKLMKIMDVQQQQEAMSSEDRFQELVDSLKPRTAHQ
YKTYYTKYIQWCQLNQIIPTPEDNSVNSVPYKDLPISAELIHWFLLDTLITDDKPGEK
REETEDLDEEEENSFKIATLKKIIGSLNFLSKLCKVHENPNANIDTKYLESVTKLHTH
WIDSQKAITTNETNNTNTQVLCPPLLKVSLNLWNPETNHLSEKFFKTCSEKLRFLVDF
QLRSYLNLSFEERSKIRFGSLKLGKRDRDAIIYHKVTHSAEKKDTPGHHQLLALLPQD
CPFICPQTTLAAYLYLRFYGIPSVSKGDGFPNLNADENGSLLQDIPILRGKSLTTYPR
EETFSNYYTTVFRYCHLPYKRREYFNKCNLVYPTWDEDTFRTFFNEENHGNWLEQPEA
FAFPDKIPFDFKKIMNFKSPYTSYSTNAKKDPFPPPKDLLVQIFPEIDEYKRHDYEGL
SQNSRDFLDLMEVLRERFLSNLPWIYKFFPNHDIFQDPIFGNSDFQSYFNDKTIHSKG
SPILSFDILPGFNKIYKNKTNFYSLLIERPSQLTFASSHNPDTHPTQKQESEGPLQMS
QLDTTQLNELLKQQSFEYVQFQTLSNFQILLSVFNKIFEKLEMKKSSRGYILHQLNLF
KITLDERIKKSKIDDADKFIRDNQPIKKEENIVNEDGPNTSRRTKRPKQIRLLSIADS
SDESSTEDSNVFKKDGESIEDGAYGENEDENDSEMQEQLKSMINELINSKISTFLRDQ
MDQFELKINALLDKILEEKVTRIIEQKLGSHTGKFSTLKRPQLYMTEEHNVGFDMEVP
KKLRTSGKYAETVKDNDDHQAMSTTASPSPEQDQEAKSYTDEQEFMLDKSIDSIEGII
LEWFTPNAKYANQCVHSMNKSGNKSWRANCEALYKERKSIVEFYIYLVNHESLDRYKA
VDICEKLRDQNEGSFSRLAKFLRKWRHDHQNSFDGLLVYLSN"
gene 770569..771972
/gene="VPS62"
/locus_tag="YGR141W"
/db_xref="GeneID:853042"
mRNA 770569..771972
/gene="VPS62"
/locus_tag="YGR141W"
/product="Vps62p"
/transcript_id="NM_001181270.1"
/db_xref="GI:296145171"
/db_xref="GeneID:853042"
CDS 770569..771972
/gene="VPS62"
/locus_tag="YGR141W"
/note="Vacuolar protein sorting (VPS) protein required for
cytoplasm to vacuole targeting of proteins"
/codon_start=1
/product="Vps62p"
/protein_id="NP_011657.1"
/db_xref="GI:6321580"
/db_xref="SGD:S000003373"
/db_xref="GeneID:853042"
/translation="MRISKNSHKRQRTRLYFLVTFIIYSIIPCRAVLVPWLDDDPFEA
TLLEMGDEPWSKDILSSTPPLHPSEVTEDNKSLKQRGNVPQYVIDNSPLLHLYSEEKY
WPADVKDFVKRFQLRDHSGEKIINEHLRDLSDLQEYYSVELENGTWGRVSSEGTYMTS
LDDFDKGPDWLLGEQPEYGTGHIKKAPAVLFVVDKGNGWVDAFWFYFYPFNWGPYIMG
SGPWGNHVGDWEHSLVRFYKGEPQYLWMSAHGGGSAYKFEAIEKIKRLRRVDGKLTNE
VIKKPLIFSARGTHAHYASVGQHAHDVPFFFMPLSDFTDRGPLWDPSLNYYAYTVTVG
EKMTPCGAEETKMGLEWLSFKGAWGDKQLRPRDPRQKWCPFQWKYIDGPKGPLFKNME
RVSLCQRFKWWNFWKGCPARRYIKRGEGLDAEKNDLVGDNCGILLYNIRPKWLRSILR
FLTWRGSVCFIMDYFTG"
gene 772454..773686
/gene="BTN2"
/locus_tag="YGR142W"
/db_xref="GeneID:853043"
mRNA 772454..773686
/gene="BTN2"
/locus_tag="YGR142W"
/product="Btn2p"
/transcript_id="NM_001181271.3"
/db_xref="GI:398365868"
/db_xref="GeneID:853043"
CDS 772454..773686
/gene="BTN2"
/locus_tag="YGR142W"
/note="v-SNARE binding protein; facilitates specific
protein retrieval from a late endosome to the Golgi;
modulates arginine uptake, possible role in mediating pH
homeostasis between the vacuole and plasma membrane
H(+)-ATPase; BTN2 has a paralog, CUR1, that arose from the
whole genome duplication"
/codon_start=1
/product="Btn2p"
/protein_id="NP_011658.3"
/db_xref="GI:398365869"
/db_xref="SGD:S000003374"
/db_xref="GeneID:853043"
/translation="MFSIFNSPCVFEQLPSFSQPLHSRYFDCSSPVSYYPECKRRKAI
KANLRAPKKSDANCSEPLRYALAETPNGYTLSLSKRIPYELFSKYVNEKLGELKENHY
RPTYHVVQDFFGNQYYVEDEADEDALLRSALKDLDFRAIGKKIAKDLFQDYEIELNHR
GDELSILSKKDKIFKEFSLDQVFEDVFVIGCGVENIDDGSREKYALLKIGLVKHEEEI
SEGGINEPKMPIIESKIDESHDDVNMSESLKEEEAEKAKEPLTKEDQIKKWIEEERLM
QEESRKSEQEKAAKEDEERQKKEKEARLKARKESLINKQKTKRSQQKKLQNSKSLPIS
EIEASNKNNNSNSGSAESDNESINSDSDTTLDFSVSGNTLKKHASPLLEDVEDEEVDR
YNESLSRSPKGNSIIEEI"
LTR 774040..774162
/note="Ty1 LTR"
/db_xref="SGD:S000006970"
gene 774349..774421
/locus_tag="tA(AGC)G"
/db_xref="GeneID:853044"
tRNA 774349..774421
/locus_tag="tA(AGC)G"
/product="tRNA-Ala"
/note="Alanine tRNA (tRNA-Ala), predicted by tRNAscan-SE
analysis; one of 11 nuclear tRNA genes containing the
tDNA-anticodon AGC (converted to IGC in the mature tRNA),
decodes GCU and GCC codons into alanine, one of 16 nuclear
tRNAs for alanine"
/db_xref="SGD:S000006512"
/db_xref="GeneID:853044"
gene 775193..777508
/gene="SKN1"
/locus_tag="YGR143W"
/db_xref="GeneID:853045"
mRNA 775193..777508
/gene="SKN1"
/locus_tag="YGR143W"
/product="Skn1p"
/transcript_id="NM_001181272.3"
/db_xref="GI:398365874"
/db_xref="GeneID:853045"
CDS 775193..777508
/gene="SKN1"
/locus_tag="YGR143W"
/note="Protein involved in sphingolipid biosynthesis; type
II membrane protein with similarity to Kre6p"
/codon_start=1
/product="Skn1p"
/protein_id="NP_011659.3"
/db_xref="GI:398365875"
/db_xref="SGD:S000003375"
/db_xref="GeneID:853045"
/translation="MSVRNLTNNRHSNSENSVSGSENSFYSSNEQSRQSSSLEPADGQ
NVRVSGNPFLGSEEFDEDYNSPSGDDERRGANEYSSSSSINYNNDPNSDTSLLANEKN
SPERNGQRMSDYKGYYAKTNLTSANNLNNHNNNNYKNIISSSNDNSFASHLQPPDRNL
PSHPSSNNMSSFSNNSLIKSPPPFDRYPLVGTRHISAAQSQSQNLINEKKRANMTGSS
SSAHDSSLSSTNLYMGEQDFSPFGGYPASFFPLTLDEKEDDDYIHNPNVEEEAKLDRR
RFVDDFKHMDRRSFLGLLGILFLFMAGIFIFIVLPAITFSGVVYHHEHVHAANSAGSS
SSNTTSKSLTEYQYPQLAAIRTTLVDPDTPDSAKTRVAKDGSKWQLVFSDEFNAEGRT
FYDGDDQFWTAPDIHYDATKDLEWYSPDAVTTTNGTLTLRMDAFRNHDLYYRSGMVQS
WNKLCFTEGALEVSANLPNYGRVTGLWPGMWTMGNLGRPGYLASTQGVWPYSYEACDA
GITPNQSSPDGISYLPGQKLSVCTCDNEDHPNQGVGRGAPEIDILEGEADTILGVGVA
SQSLQIAPFDIWYMPDYDFIEVYNFTTTTMNTYAGGPFQQAVSAISTLNVTWYEFGEE
AGYFQKYAIEYLNDDDNGYIRWFVGENPTFTLYATSLHPSGNIDWRRISKEPMSAILN
LGISNNWAYIDWQYIFFPVTMSIDYVRLYQPKGSTSITCDPEDYPTYDYIQSHLNAYY
NANLTDWEQAGYTFPKNILTGGCSSSKFSLS"
rep_origin 777966..778214
/note="ARS729;
Autonomously Replicating Sequence"
/db_xref="SGD:S000118465"
LTR 778784..779112
/note="Ty1 LTR"
/db_xref="SGD:S000006971"
LTR 779116..779224
/note="Ty1 LTR"
/db_xref="SGD:S000006972"
LTR complement(779225..779515)
/note="Ty1 LTR"
/db_xref="SGD:S000006958"
gene 779616..779687
/gene="SUF4"
/locus_tag="tG(UCC)G"
/db_xref="GeneID:853046"
tRNA 779616..779687
/gene="SUF4"
/locus_tag="tG(UCC)G"
/product="tRNA-Gly"
/note="Glycine tRNA (tRNA-Gly), predicted by tRNAscan-SE
analysis; can mutate to suppress +1 frameshift mutations
in glycine codons"
/db_xref="SGD:S000006590"
/db_xref="GeneID:853046"
gene 780399..781379
/gene="THI4"
/locus_tag="YGR144W"
/gene_synonym="ESP35; MOL1"
/db_xref="GeneID:853047"
mRNA 780399..781379
/gene="THI4"
/locus_tag="YGR144W"
/gene_synonym="ESP35; MOL1"
/product="Thi4p"
/transcript_id="NM_001181273.1"
/db_xref="GI:296145174"
/db_xref="GeneID:853047"
CDS 780399..781379
/gene="THI4"
/locus_tag="YGR144W"
/gene_synonym="ESP35; MOL1"
/note="Thiazole synthase, abundant protein involved in the
formation of the thiazole moiety of thiamine during
thiamine biosynthesis; acts more as a co-substrate rather
than an enzyme by providing the sulphur source for
thiazole formation; undergoes a single turnover only;
required for mitochondrial genome stability in response to
DNA damaging agents"
/codon_start=1
/product="Thi4p"
/protein_id="NP_011660.1"
/db_xref="GI:6321583"
/db_xref="SGD:S000003376"
/db_xref="GeneID:853047"
/translation="MSATSTATSTSASQLHLNSTPVTHCLSDIVKKEDWSDFKFAPIR
ESTVSRAMTSRYFKDLDKFAVSDVIIVGAGSSGLSAAYVIAKNRPDLKVCIIESSVAP
GGGSWLGGQLFSAMVMRKPAHLFLQELEIPYEDEGDYVVVKHAALFISTVLSKVLQLP
NVKLFNATCVEDLVTRPPTEKGEVTVAGVVTNWTLVTQAHGTQCCMDPNVIELAGYKN
DGTRDLSQKHGVILSTTGHDGPFGAFCAKRIVDIDQNQKLGGMKGLDMNHAEHDVVIH
SGAYAGVDNMYFAGMEVAELDGLNRMGPTFGAMALSGVHAAEQILKHFAA"
gene 781767..783890
/gene="ENP2"
/locus_tag="YGR145W"
/db_xref="GeneID:853048"
mRNA 781767..783890
/gene="ENP2"
/locus_tag="YGR145W"
/product="Enp2p"
/transcript_id="NM_001181274.2"
/db_xref="GI:330443567"
/db_xref="GeneID:853048"
CDS 781767..783890
/gene="ENP2"
/locus_tag="YGR145W"
/note="Essential nucleolar protein, required for
biogenesis of the small ribosomal subunit; contains WD
repeats, interacts with Mpp10p and Bfr2p, and has homology
to Spb1p"
/codon_start=1
/product="Enp2p"
/protein_id="NP_011661.2"
/db_xref="GI:330443568"
/db_xref="SGD:S000003377"
/db_xref="GeneID:853048"
/translation="MVLKSTSANDVSVYQVSGTNVSRSLPDWIAKKRKRQLKNDLEYQ
NRVELIQDFEFSEASNKIKVSRDGQYCMATGTYKPQIHVYDFANLSLKFDRHTDAENV
DFTILSDDWTKSVHLQNDRSIQFQNKGGLHYTTRIPKFGRSLVYNKVNCDLYVGASGN
ELYRLNLEKGRFLNPFKLDTEGVNHVSINEVNGLLAAGTETNVVEFWDPRSRSRVSKL
YLENNIDNRPFQVTTTSFRNDGLTFACGTSNGYSYIYDLRTSEPSIIKDQGYGFDIKK
IIWLDNVGTENKIVTCDKRIAKIWDRLDGKAYASMEPSVDINDIEHVPGTGMFFTANE
SIPMHTYYIPSLGPSPRWCSFLDSITEELEEKPSDTVYSNYRFITRDDVKKLNLTHLV
GSRVLRAYMHGFFINTELYDKVSLIANPDAYKDEREREIRRRIEKERESRIRSSGAVQ
KPKIKVNKTLVDKLSQKRGDKVAGKVLTDDRFKEMFEDEEFQVDEDDYDFKQLNPVKS
IKETEEGAAKRIRALTAAEESDEERIAMKDGRGHYDYEDEESDEEESDDETNQKSNKE
ELSEKDLRKMEKQKALIERRKKEKEQSERFMNEMKAGTSTSTQRDESAHVTFGEQVGE
LLEVENGKKSNESILRRNQRGEAELTFIPQRKSKKDGNYKSRRHDNSSDEEGIDENGN
KKDNGRSKPRFENRRRASKNAFRGM"
gene complement(784223..784858)
/gene="ECL1"
/locus_tag="YGR146C"
/db_xref="GeneID:853049"
mRNA complement(784223..784858)
/gene="ECL1"
/locus_tag="YGR146C"
/product="Ecl1p"
/transcript_id="NM_001181275.3"
/db_xref="GI:398365888"
/db_xref="GeneID:853049"
CDS complement(784223..784858)
/gene="ECL1"
/locus_tag="YGR146C"
/note="hypothetical protein; mitochondrial-dependent role
in the extension of chronological lifespan; overexpression
increases oxygen consumption and respiratory activity
while deletion results in reduced oxygen consumption under
conditions of caloric restriction; induced by iron
homeostasis transcription factor Aft2p; multicopy
suppressor of temperature sensitive hsf1 mutant; induced
by treatment with 8-methoxypsoralen and UVA irradiation"
/codon_start=1
/product="Ecl1p"
/protein_id="NP_011662.3"
/db_xref="GI:398365889"
/db_xref="SGD:S000003378"
/db_xref="GeneID:853049"
/translation="MSTAFNDYCTVCDRLIPTSPQKTNINTRKIQRDNETKSSLQSNK
LYCSEDCKLKDSNPLNEKLLSHLHKKSKTSHSHNLTPPLSYSKNLTASNLFEPTTSLS
SSPTSSTIPFDELEKLESLLISPLLLPQDGIVNPKQESNPSRVDEYDENEHYLNLADS
LRLDSSYQLHSKAHLGYENNLPRSNDLIDDHLISDQIIENNYNLWFRLSSS"
gene complement(785276..785437)
/locus_tag="YGR146C-A"
/db_xref="GeneID:1466459"
mRNA complement(785276..785437)
/locus_tag="YGR146C-A"
/product="hypothetical protein"
/transcript_id="NM_001184594.1"
/db_xref="GI:296145177"
/db_xref="GeneID:1466459"
CDS complement(785276..785437)
/locus_tag="YGR146C-A"
/codon_start=1
/product="hypothetical protein"
/protein_id="NP_878079.1"
/db_xref="GI:33438797"
/db_xref="SGD:S000028638"
/db_xref="GeneID:1466459"
/translation="MGFLPECNLTCAFLLHSFTFPIAHCPSFSWASFFFTIRPPFFPK
LALVCTIFS"
gene complement(786054..786920)
/gene="NAT2"
/locus_tag="YGR147C"
/db_xref="GeneID:853050"
mRNA complement(786054..786920)
/gene="NAT2"
/locus_tag="YGR147C"
/product="Nat2p"
/transcript_id="NM_001181276.3"
/db_xref="GI:398365904"
/db_xref="GeneID:853050"
CDS complement(786054..786920)
/gene="NAT2"
/locus_tag="YGR147C"
/EC_number="2.3.1.88"
/note="Protein with an apparent role in acetylation of
N-terminal methionine residues"
/codon_start=1
/product="Nat2p"
/protein_id="NP_011663.3"
/db_xref="GI:398365905"
/db_xref="SGD:S000003379"
/db_xref="GeneID:853050"
/translation="MMVPRISASPVFKRIFLRWGFVTLPIQKTVSHTLRRDFSAPCRS
MVKCLLLRPGISVHSAQDRKFYSTEEKSSQFDENKSKSNNGKKNEPHGIKGLMAKYGY
SALIVYILLTCVDLPLCFLGVHSLGEEKIKIYLNRGKQLIGMGEPDESKVIQDVRRKQ
AHREAVQAENADKVEDASRKTFNERWQEMKDSTLLAELLIAYGIHKSLIIVRVPLTAV
LTPSFVKLLQRFGIDLMKKQKKVFQTMASGAKIRYKGNNPSDFIKNEGTALDITKRKP
RTKGQKWFDGLM"
gene complement(787312..787779)
/gene="RPL24B"
/locus_tag="YGR148C"
/gene_synonym="RPL30B"
/db_xref="GeneID:853051"
mRNA complement(787312..787779)
/gene="RPL24B"
/locus_tag="YGR148C"
/gene_synonym="RPL30B"
/product="ribosomal 60S subunit protein L24B"
/transcript_id="NM_001181277.3"
/db_xref="GI:398365908"
/db_xref="GeneID:853051"
CDS complement(787312..787779)
/gene="RPL24B"
/locus_tag="YGR148C"
/gene_synonym="RPL30B"
/note="Ribosomal 60S subunit protein L24B; not essential
for translation but may be required for normal translation
rate; homologous to mammalian ribosomal protein L24, no
bacterial homolog; RPL24B has a paralog, RPL24A, that
arose from the whole genome duplication"
/codon_start=1
/product="ribosomal 60S subunit protein L24B"
/protein_id="NP_011664.3"
/db_xref="GI:398365909"
/db_xref="SGD:S000003380"
/db_xref="GeneID:853051"
/translation="MKVEVDSFSGAKIYPGRGTLFVRGDSKIFRFQNSKSASLFKQRK
NPRRIAWTVLFRKHHKKGITEEVAKKRSRKTVKAQRPITGASLDLIKERRSLKPEVRK
ANREEKLKANKEKKRAEKAARKAEKAKSAGVQGSKVSKQQAKGAFQKVAATSR"
gene 789031..790329
/locus_tag="YGR149W"
/db_xref="GeneID:853052"
mRNA 789031..790329
/locus_tag="YGR149W"
/product="hypothetical protein"
/transcript_id="NM_001181278.1"
/db_xref="GI:296145180"
/db_xref="GeneID:853052"
CDS 789031..790329
/locus_tag="YGR149W"
/note="hypothetical protein; predicted to be an integal
membrane protein"
/codon_start=1
/product="hypothetical protein"
/protein_id="NP_011665.1"
/db_xref="GI:6321588"
/db_xref="SGD:S000003381"
/db_xref="GeneID:853052"
/translation="MYKLDNNDIDDETNNSVSLTSLLEFLDPIASKVVSKYYHGSHLS
KAEQKLRNFEGFRRRKPHHEHDSHHPHHLNRSRSFLQLEDFKVRALQRIRNLDKPLDS
IFFKNSSRLEKAFYPFTLFNIFFIGFLMGRFPEWFHVYYTILFFVLMPIRFYTYYKTK
NHYFLADFCYFVNMLCLLFIWIFPYSYSLFQSCFAFTFGTLCFAVITWRNSLVIHSID
KTTSCFIHIIPPCVMYVIYHGLPLEYKIERFPGAIIQSELDIKKNILWTSLYYLVWQS
LYHYFITLKKSSKIKSGERMTSFEYLTTHQFKNFWAVKLRSPWPMIIYTLSQYFYQLF
TMLLCGIWIRYKLAAALFLTIVFLWASHNGATYYIDHYGKNFEKEVDRLRLEVENLQQ
KLQPDSDAVISDASVNDKDYLNVNRDEDFDDSSSVSSKSD"
gene complement(790459..793053)
/gene="CCM1"
/locus_tag="YGR150C"
/gene_synonym="DMR1; RRG2"
/db_xref="GeneID:853053"
mRNA complement(790459..793053)
/gene="CCM1"
/locus_tag="YGR150C"
/gene_synonym="DMR1; RRG2"
/product="Ccm1p"
/transcript_id="NM_001181279.1"
/db_xref="GI:296145181"
/db_xref="GeneID:853053"
CDS complement(790459..793053)
/gene="CCM1"
/locus_tag="YGR150C"
/gene_synonym="DMR1; RRG2"
/note="Mitochondrial 15s rRNA-binding protein; required
for intron removal of COB and COX1 pre-mRNAs; contains
pentatricopeptide repeat (PPR) motifs; mutant is
respiratory deficient and has defective plasma membrane
electron transport"
/codon_start=1
/product="Ccm1p"
/protein_id="NP_011666.1"
/db_xref="GI:6321589"
/db_xref="SGD:S000003382"
/db_xref="GeneID:853053"
/translation="MYMARCGPKNNVLCFPFQLSFLFSKRLINKRFKYTLQTEDEKNM
MGSLSKNKIITPEDVEFKLAQLREFSNTLKERIHNTKSVNSDGHQSNSIAPISEDSRN
VNVTKTSSVPNEEKSKNLSDLIHSSFLEKMDHLVPKVIRERVADDDILAKNLFDRSHS
NWAPVIDRLYVSEKRFMDIDSREFSVWLNGTVKYLPFHSILHLDEMLLEQINGDVVKF
NTHMYECIFNNLGNLKPTNFNQDGTNDKVILKMKELLERYDKALKITEERINKKEGFP
SKVPKMTQAILNNCLKYSTKCSSFHDMDYFITKFRDDYGITPNKQNLTTVIQFYSRKE
MTKQAWNTFDTMKFLSTKHFPDICTYNTMLRICEKERNFPKALDLFQEIQDHNIKPTT
NTYIMMARVLASSSSNAVVSEGKSDSLRLLGWKYLHELEDKNLYRHKKDDLNLFLAMM
ALAAFDGDIELSRALYYLFIAKKYKTLCANWKGNILVDQDTIWKSTLMPEMLNYLMLA
YARFDPRNLPVLSGYEKGIELRRKFLREFDSSMRLDDTDKLVKFKLPFLPISDLNSEA
QVLAESNAIWSFNMENGGTRNTLTSSNEAALEDIKKYRQLLDSFAQEAEDFNEFKFKV
MYEVTKMQRESINVNVFNKISLHTYLSIPINLKQQKEFLRRLTFFTFQQHEFEAVIKR
LYEGYRNIPSSHTRDQNSISTEAISVSKPETTEDLNLIMHDIWYITCLRHKIMMDTTL
YELVMKAAIEFQNEDLAKKVWNDRGKFRTTVPFLKMDQRIRIAKDQKFAHLMVEFFTK
QGKYSDAIAIILSSKNRFNWTYSMVRNLHKALEEIEDRNSVEILLDVVNKKSHAKALK
WEEQELNM"
LTR 793237..793559
/note="Ty1 LTR"
/db_xref="SGD:S000006973"
gene 794417..794489
/locus_tag="tA(UGC)G"
/db_xref="GeneID:853054"
tRNA 794417..794489
/locus_tag="tA(UGC)G"
/product="tRNA-Ala"
/note="Alanine tRNA (tRNA-Ala), predicted by tRNAscan-SE
analysis; one of 5 nuclear tRNA genes containing the
tDNA-anticodon TGC (mature tRNA may be UGC or may contain
modified bases), decodes GCA and probably GCG codons into
alanine, one of 16 nuclear tRNAs for alanine"
/db_xref="SGD:S000006523"
/db_xref="GeneID:853054"
gene complement(794674..795492)
/gene="RSR1"
/locus_tag="YGR152C"
/gene_synonym="BUD1"
/db_xref="GeneID:853056"
mRNA complement(794674..795492)
/gene="RSR1"
/locus_tag="YGR152C"
/gene_synonym="BUD1"
/product="Rsr1p"
/transcript_id="NM_001181281.3"
/db_xref="GI:398365916"
/db_xref="GeneID:853056"
CDS complement(794674..795492)
/gene="RSR1"
/locus_tag="YGR152C"
/gene_synonym="BUD1"
/note="GTP-binding protein of the ras superfamily required
for bud site selection, morphological changes in response
to mating pheromone, and efficient cell fusion; localized
to the plasma membrane; significantly similar to mammalian
Rap GTPases"
/codon_start=1
/product="Rsr1p"
/protein_id="NP_011668.3"
/db_xref="GI:398365917"
/db_xref="SGD:S000003384"
/db_xref="GeneID:853056"
/translation="MRDYKLVVLGAGGVGKSCLTVQFVQGVYLDTYDPTIEDSYRKTI
EIDNKVFDLEILDTAGIAQFTAMRELYIKSGMGFLLVYSVTDRQSLEELMELREQVLR
IKDSDRVPMVLIGNKADLINERVISVEEGIEVSSKWGRVPFYETSALLRSNVDEVFVD
LVRQIIRNEMESVAVKDARNQSQQFSKIESPSTRLPSSAKQDTKQSNNKQSSKGLYNK
SSQGQAKVKQSTPVNEKHKPSHAVPKSGSSNRTGISATSQQKKKKKNASTCTIL"
gene 796092..796745
/locus_tag="YGR153W"
/db_xref="GeneID:853057"
mRNA 796092..796745
/locus_tag="YGR153W"
/product="hypothetical protein"
/transcript_id="NM_001181282.2"
/db_xref="GI:330443569"
/db_xref="GeneID:853057"
CDS 796092..796745
/locus_tag="YGR153W"
/codon_start=1
/product="hypothetical protein"
/protein_id="NP_011669.2"
/db_xref="GI:330443570"
/db_xref="SGD:S000003385"
/db_xref="GeneID:853057"
/translation="MGKACLNKEVGTYECEGERDTYSFFTSLSDIQDSSSNEEQCGVG
SILSEDSFTFEGSNVSIRLFSLDLNALNENENGSKNPVKFTIPPKIEQRKEARQREKR
LRRVAVLPENSRNYLVESSMDSSREYSQPFFDWRHEMVEHGEESVKPCGCHKSRKAKC
FKELEMENIEKGDIKKSLFYRDIIEWCRDYEVNKTREVCVPSIHEFYLHGNGSDNLF"
gene complement(796798..797868)
/gene="GTO1"
/locus_tag="YGR154C"
/db_xref="GeneID:853058"
mRNA complement(796798..797868)
/gene="GTO1"
/locus_tag="YGR154C"
/product="Gto1p"
/transcript_id="NM_001181283.3"
/db_xref="GI:398365926"
/db_xref="GeneID:853058"
CDS complement(796798..797868)
/gene="GTO1"
/locus_tag="YGR154C"
/EC_number="2.5.1.18"
/note="Omega-class glutathione transferase; induced under
oxidative stress; putative peroxisomal localization"
/codon_start=1
/product="Gto1p"
/protein_id="NP_011670.3"
/db_xref="GI:398365927"
/db_xref="SGD:S000003386"
/db_xref="GeneID:853058"
/translation="MSVSYKGTISKTHSVFKPEKGRYYIYGALGCPFTHRAILARSLK
KLEPVLGLVLSHWQLDSKGARFLPAPHRPEKYKERFFTATGGIASAKLDESEELGDVN
NDSARLFVDGAFDPVENISRLSELYYLNDPKYPGTKFTVPVLWDSKTRKIVNNESGDI
IRILNSGVFDEFIQSEETNVIDLVPHDLIDEIDKNIKWVHPKINLGVYKVGLAENGKI
YETEVKTLFENLQKMECVLKENYKRLEEQFSGNKQKILAKYFVLGQRLTEADIRLYPS
IIRFDVVYVQHFKCNLKTIRDGFPYLHLWLINLYWNYAEFRFTTDFNHIKLFYIRMEV
SRNKINQFGIVPLGPKPDISRL"
gene 798543..800066
/gene="CYS4"
/locus_tag="YGR155W"
/gene_synonym="NHS5; STR4; VMA41"
/db_xref="GeneID:853059"
mRNA 798543..800066
/gene="CYS4"
/locus_tag="YGR155W"
/gene_synonym="NHS5; STR4; VMA41"
/product="cystathionine beta-synthase CYS4"
/transcript_id="NM_001181284.3"
/db_xref="GI:398365932"
/db_xref="GeneID:853059"
CDS 798543..800066
/gene="CYS4"
/locus_tag="YGR155W"
/gene_synonym="NHS5; STR4; VMA41"
/EC_number="4.2.1.22"
/note="Cystathionine beta-synthase, catalyzes synthesis of
cystathionine from serine and homocysteine, the first
committed step in cysteine biosynthesis; responsible for
hydrogen sulfide generation; advances passage through
START by promoting cell growth which requires catalytic
activity, and reducing critical cell size independent of
catalytic activity; mutations in human ortholog cause
homocystinuria"
/codon_start=1
/product="cystathionine beta-synthase CYS4"
/protein_id="NP_011671.3"
/db_xref="GI:398365933"
/db_xref="SGD:S000003387"
/db_xref="GeneID:853059"
/translation="MTKSEQQADSRHNVIDLVGNTPLIALKKLPKALGIKPQIYAKLE
LYNPGGSIKDRIAKSMVEEAEASGRIHPSRSTLIEPTSGNTGIGLALIGAIKGYRTII
TLPEKMSNEKVSVLKALGAEIIRTPTAAAWDSPESHIGVAKKLEKEIPGAVILDQYNN
MMNPEAHYFGTGREIQRQLEDLNLFDNLRAVVAGAGTGGTISGISKYLKEQNDKIQIV
GADPFGSILAQPENLNKTDITDYKVEGIGYDFVPQVLDRKLIDVWYKTDDKPSFKYAR
QLISNEGVLVGGSSGSAFTAVVKYCEDHPELTEDDVIVAIFPDSIRSYLTKFVDDEWL
KKNNLWDDDVLARFDSSKLEASTTKYADVFGNATVKDLHLKPVVSVKETAKVTDVIKI
LKDNGFDQLPVLTEDGKLSGLVTLSELLRKLSINNSNNDNTIKGKYLDFKKLNNFNDV
SSYNENKSGKKKFIKFDENSKLSDLNRFFEKNSSAVITDGLKPIHIVTKMDLLSYLA"
gene 800546..801823
/gene="PTI1"
/locus_tag="YGR156W"
/db_xref="GeneID:853060"
mRNA 800546..801823
/gene="PTI1"
/locus_tag="YGR156W"
/product="Pti1p"
/transcript_id="NM_001181285.1"
/db_xref="GI:296145186"
/db_xref="GeneID:853060"
CDS 800546..801823
/gene="PTI1"
/locus_tag="YGR156W"
/note="Essential protein that is a component of CPF
(cleavage and polyadenylation factor); involved in 3' end
formation of snoRNA and mRNA; interacts directly with
Pta1p; has similarity to mammalian Cleavage-Stimulation
Factor CstF-64"
/codon_start=1
/product="Pti1p"
/protein_id="NP_011672.1"
/db_xref="GI:6321595"
/db_xref="SGD:S000003388"
/db_xref="GeneID:853060"
/translation="MTDPRRRTGRHFLTPENLSSTLQITNLPPEWNQDIITSVVAGSG
PVIDIKAKNDPRTGKLTGVLFDYLTSKDCKRAWEILNRIENFPVKIEQIIPPNYKDHL
RETANKNSQKQVLQLNRDSYPFEAGLELPFEMVTEVPIPRRPPPPQAANNTNSVSNNT
NIQFPDILSKASKHLPSFQDGSIIAPDKISQNLSKIPPLQLIEIISNLKILSNQENIQ
KSQLESFLDTNSDITISVTQALLEMGFIDYSVVTKVLKSQVGEAPSLLSSNNTSNSNT
PVSVIRNNTPLHVPSNEVSNNPNNMPLNVAMPMPMSTPPFIPLPLQQQPFGFAPPGPF
MPPAQGPSMGQPVLANQLGQVQQQNISSTEGPSNANKANDSGTINMAKLQLLPENQQD
MIKQVLTLTPAQIQSLPSDQQLMVENFRKEYII"
gene 802440..805049
/gene="CHO2"
/locus_tag="YGR157W"
/gene_synonym="PEM1"
/db_xref="GeneID:853061"
mRNA 802440..805049
/gene="CHO2"
/locus_tag="YGR157W"
/gene_synonym="PEM1"
/product="phosphatidylethanolamine N-methyltransferase"
/transcript_id="NM_001181286.1"
/db_xref="GI:296145187"
/db_xref="GeneID:853061"
CDS 802440..805049
/gene="CHO2"
/locus_tag="YGR157W"
/gene_synonym="PEM1"
/EC_number="2.1.1.17"
/note="Phosphatidylethanolamine methyltransferase (PEMT),
catalyzes the first step in the conversion of
phosphatidylethanolamine to phosphatidylcholine during the
methylation pathway of phosphatidylcholine biosynthesis"
/codon_start=1
/product="phosphatidylethanolamine N-methyltransferase"
/protein_id="NP_011673.1"
/db_xref="GI:6321596"
/db_xref="SGD:S000003389"
/db_xref="GeneID:853061"
/translation="MSSCKTTLSEMVGSVTKDRGTINVEARTRSSNVTFKPPVTHDMV
RSLFDPTLKKSLLEKCIALAIISNFFICYWVFQRFGLQFTKYFFLVQYLFWRIAYNLG
IGLVLHYQSHYETLTNCAKTHAIFSKIPQNKDANSNFSTNSNSFSEKFWNFIRKFCQY
EIRSKMPKEYDLFAYPEEINVWLIFRQFVDLILMQDFVTYIIYVYLSIPYSWVQIFNW
RSLLGVILILFNIWVKLDAHRVVKDYAWYWGDFFFLEESELIFDGVFNISPHPMYSIG
YLGYYGLSLICNDYKVLLVSVFGHYSQFLFLKYVENPHIERTYGDGTDSDSQMNSRID
DLISKENYDYSRPLINMGLSFNNFNKLRFTDYFTIGTVAALMLGTIMNARFINLNYLF
ITVFVTKLVSWLFISTILYKQSQSKWFTRLFLENGYTQVYSYEQWQFIYNYYLVLTYT
LMIIHTGLQIWSNFSNINNSQLIFGLILVALQTWCDKETRLAISDFGWFYGDFFLSNY
ISTRKLTSQGIYRYLNHPEAVLGVVGVWGTVLMTNFAVTNIILAVLWTLTNFILVKFI
ETPHVNKIYGKTKRVSGVGKTLLGLKPLRQVSDIVNRIENIIIKSLVDESKNSNGGAE
LLPKNYQDNKEWNILIQEAMDSVATRLSPYCELKIENEQVETNFVLPTPVTLNWKMPI
ELYNGDDWIGLYKVIDTRADREKTRVGSGGHWSATSKDSYMNHGLRHKESVTEIKATE
KYVQGKVTFDTSLLYFENGIYEFRYHSGNSHKVLLISTPFEISLPVLNTTTPELFEKD
LTEFLTKVNVLKDGKFRPLGNKFFGMDSLKQLIKNSIGVELSSEYMRRVNGDAHVISH
RAWDIKQTLDSLA"
gene complement(805269..806021)
/gene="MTR3"
/locus_tag="YGR158C"
/db_xref="GeneID:853062"
mRNA complement(805269..806021)
/gene="MTR3"
/locus_tag="YGR158C"
/product="Mtr3p"
/transcript_id="NM_001181287.3"
/db_xref="GI:398365938"
/db_xref="GeneID:853062"
CDS complement(805269..806021)
/gene="MTR3"
/locus_tag="YGR158C"
/EC_number="3.1.13.-"
/note="Exosome non-catalytic core component; involved in
3'-5' RNA processing and degradation in both the nucleus
and the cytoplasm; has similarity to E. coli RNase PH and
to human hMtr3p (EXOSC6)"
/codon_start=1
/product="Mtr3p"
/protein_id="NP_011674.3"
/db_xref="GI:398365939"
/db_xref="SGD:S000003390"
/db_xref="GeneID:853062"
/translation="MNVQDRRRLLGPAAAKPMAFSNTTTHVPEKKSTDLTPKGNESEQ
ELSLHTGFIENCNGSALVEARSLGHQTSLITAVYGPRSIRGSFTSQGTISIQLKNGLL
EKYNTNELKEVSSFLMGIFNSVVNLSRYPKSGIDIFVYLTYDKDLTNNPQDDDSQSKM
MSSQISSLIPHCITSITLALADAGIELVDMAGAGEANGTVVSFIKNGEEIVGFWKDDG
DDEDLLECLDRCKEQYNRYRDLMISCLMNQET"
gene complement(806412..807656)
/gene="NSR1"
/locus_tag="YGR159C"
/gene_synonym="SHE5"
/db_xref="GeneID:853064"
mRNA complement(806412..807656)
/gene="NSR1"
/locus_tag="YGR159C"
/gene_synonym="SHE5"
/product="Nsr1p"
/transcript_id="NM_001181288.1"
/db_xref="GI:296145189"
/db_xref="GeneID:853064"
CDS complement(806412..807656)
/gene="NSR1"
/locus_tag="YGR159C"
/gene_synonym="SHE5"
/note="Nucleolar protein that binds nuclear localization
sequences, required for pre-rRNA processing and ribosome
biogenesis"
/codon_start=1
/product="Nsr1p"
/protein_id="NP_011675.1"
/db_xref="GI:6321599"
/db_xref="SGD:S000003391"
/db_xref="GeneID:853064"
/translation="MAKTTKVKGNKKEVKASKQAKEEKAKAVSSSSSESSSSSSSSSE
SESESESESESSSSSSSSDSESSSSSSSDSESEAETKKEESKDSSSSSSDSSSDEEEE
EEKEETKKEESKESSSSDSSSSSSSDSESEKEESNDKKRKSEDAEEEEDEESSNKKQK
NEETEEPATIFVGRLSWSIDDEWLKKEFEHIGGVIGARVIYERGTDRSRGYGYVDFEN
KSYAEKAIQEMQGKEIDGRPINCDMSTSKPAGNNDRAKKFGDTPSEPSDTLFLGNLSF
NADRDAIFELFAKHGEVVSVRIPTHPETEQPKGFGYVQFSNMEDAKKALDALQGEYID
NRPVRLDFSSPRPNNDGGRGGSRGFGGRGGGRGGNRGFGGRGGARGGRGGFRPSGSGA
NTAPLGRSRNTASFAGSKKTFD"
gene complement(808629..809420)
/gene="RTS3"
/locus_tag="YGR161C"
/db_xref="GeneID:853065"
mRNA complement(808629..809420)
/gene="RTS3"
/locus_tag="YGR161C"
/product="Rts3p"
/transcript_id="NM_001181290.3"
/db_xref="GI:398365944"
/db_xref="GeneID:853065"
CDS complement(808629..809420)
/gene="RTS3"
/locus_tag="YGR161C"
/note="Putative component of the protein phosphatase type
2A complex"
/codon_start=1
/product="Rts3p"
/protein_id="NP_011677.3"
/db_xref="GI:398365945"
/db_xref="SGD:S000003393"
/db_xref="GeneID:853065"
/translation="MIATSRAVNMNKESKHKKAVAKPCRERQTSVTRAMRPAVARDPR
RLSTSSSPSSSPMSAQRRLSREEIINEMEKEQDAIVVRLLREIETLKEENSRLKNQLH
HPVPARRSSPFFEGESAILDDDDCNYGYTLDTPKLKLTDGASRHTVLPLTPKDSMTHI
SHSARRSSRNASISNGTSISDTIFPIETKIHSAPTTNRNLPSADLPHHTLLPRSLSGI
SSSDLTESGALLHDRRRRSSNYSLDGSNSLKADLMAKRFQTGSLK"
gene 810227..810505
/locus_tag="YGR161W-C"
/db_xref="GeneID:3077355"
mRNA 810227..810505
/locus_tag="YGR161W-C"
/product="hypothetical protein"
/transcript_id="NM_001184675.3"
/db_xref="GI:398365946"
/db_xref="GeneID:3077355"
CDS 810227..810505
/locus_tag="YGR161W-C"
/note="hypothetical protein; identified by sequence
comparison with hemiascomycetous yeast species"
/codon_start=1
/product="hypothetical protein"
/protein_id="NP_001018033.3"
/db_xref="GI:398365947"
/db_xref="SGD:S000029726"
/db_xref="GeneID:3077355"
/translation="MSGYFNHLSSNAHFANIQADQGFIGDATGTSSDHGSSGMVDFAL
QLGELSLEEKILKEFTLFQSKNMDLLQETATACPSTNPSLRQSRIQGW"
mobile_element 811447..817397
/note="YGRWTy2-2; Ty2 element, LTR retrotransposon of the
Copia (Pseudoviridae) group; contains co-transcribed genes
TYA Gag and TYB Pol, encoding proteins involved in
structure and function of virus-like particles, flanked by
two direct repeats"
/mobile_element_type="retrotransposon:YGRWTy2-2"
/db_xref="SGD:S000006983"
LTR 811447..811778
/note="Ty2 LTR"
/db_xref="SGD:S000006974"
gene 811738..817051
/locus_tag="YGR161W-B"
/db_xref="GeneID:853067"
mRNA join(<811738..813030,813032..>817051)
/locus_tag="YGR161W-B"
/transcript_id="NM_001184402.1"
/db_xref="GI:296145193"
/db_xref="GeneID:853067"
CDS join(811738..813030,813032..817051)
/locus_tag="YGR161W-B"
/EC_number="2.7.7.49"
/EC_number="3.4.23.-"
/EC_number="3.1.26.4"
/EC_number="2.7.7.7"
/ribosomal_slippage
/note="Retrotransposon TYA Gag and TYB Pol genes;
transcribed/translated as one unit; polyprotein is
processed to make a nucleocapsid-like protein (Gag),
reverse transcriptase (RT), protease (PR), and integrase
(IN); similar to retroviral genes"
/codon_start=1
/product="gag-pol fusion protein"
/protein_id="NP_058163.1"
/db_xref="GI:7839176"
/db_xref="SGD:S000007370"
/db_xref="GeneID:853067"
/translation="MESQQLHQNPHSLHGSAYASVTSKEVPSNQDPLAVSASNLPEFD
RDSTKVNSQQETTPGTSAVPENHHHVSPQPASVPPPQNGQYQQHGMMTPNKAMASNWA
HYQQPSMMTCSHYQTSPAYYQPDPHYPLPQYIPPLSTSSPDPIDSQNQHSEVPQAETK
VRNNVLPPHTLTSEENFSTWVKFYIRFLKNSNLGDIIPNDQGEIKSQMTYEEHAYIYN
TFQAFAPFHLLPTWVKQILEINYADILTVLCKSVSKMQTNNQELKDWIALANLEYDGS
TSADTFEITVSTIIQRLKENNINVSDRLACQLILKGLSGDFKYLRNQYRTKTNMKLSQ
LFAEIQLIYDENKIMNLNKPSQYKQHSEYKNVSRTSPNTTNTKVTTRNYHRTNSSKPR
AAKAHNIATSSKFSRVNNDHINESTVSSQYLSDDNELSLGQQQKESKPTHTIDSNDEL
PDHLLIDSGASQTLVRSAHYLHHATPNSEINIVDAQKQDIPINAIGNLHFNFQNGTKT
SIKALHTPNIAYDLLSLSELANQNITACFTRNTLERSDGTVLAPIVKHGDFYWLSKKY
LIPSHISKLTINNVNKSKSVNKYPYPLIHRMLGHANFRSIQKSLKKNAVTYLKESDIE
WSNASTYQCPDCLIGKSTKHRHVKGSRLKYQESYEPFQYLHTDIFGPVHHLPKSAPSY
FISFTDEKTRFQWVYPLHDRREESILNVFTSILAFIKNQFNARVLVIQMDRGSEYTNK
TLHKFFTNRGITACYTTTADSRAHGVAERLNRTLLNDCRTLLHCSGLPNHLWFSAVEF
STIIRNSLVSPKNDKSARQHAGLAGLDITTILPFGQPVIVNNHNPDSKIHPRGIPGYA
LHPSRNSYGYIIYLPSLKKTVDTTNYVILQDKQSKLDQFNYDTLTFDDDLNRLTAHNQ
SFIEQNETEQSYDQNTESDHDYQSEIEINSDPLVNDFSSQSINPLQLDKEPVQKVRAP
KEVDADISEYNILPSTIRSRTPHIINKESTEMGGTVESDTTSPRHSSTFTARNQNRPG
STNEMIDLTSQDRVNYGLENIKTTRLGGTEEPYIQRNSDTNIKYRTTNSTPSIDDRSS
NSESTTPIISIETKAVCDNTPSIDTDPPEYRSSDHATPNIMPDKSSKNVTADSILDDL
PLPDLTHKSPTDTSDVSKDIPHIHSRQTNSSLGGMDDSNVLTTTKSKKRSLEDNETEI
EVSRDTWNNKNMRSLEPPRSKKRINLIAAIKGVKSIKPVRTTLRYDEAITYNKDNKEK
DRYVEAYHKEISQLLKMNTWDTNKYYDRNDIDPKKVINSMFIFNKKRDGTHKARFVAR
GDIQHPDTYDSDMQSNTVHHYALMTSLSIALDNDYYITQLDISSAYLYADIKEELYIR
PPPHLGLNDKLLRLRKSLYGLKQSGANWYETIKSYLINCCDMQEVRGWSCVFKNSQVT
ICLFVDDMILFSKDLNANKKIITTLKKQYDTKIINLGESDNEIQYDILGLEIKYQRSK
YMKLGMEKSLTEKLPKLNVPLNPKGKKLRAPGQPGHYIDQDELEIDEDEYKEKVHEMQ
KLIGLASYVGYKFRFDLLYYINTLAQHILFPSRQVLDMTYELIQFMWDTRDKQLIWHK
NKPTKPDNKLVAISDASYGNQPYYKSQIGNIFLLNGKVIGGKSTKASLTCTSTTEAEI
HAVSEAIPLLNNLSHLVQELNKKPIIKGLLTDSRSTISIIKSTNEEKFRNRFFGTKAM
RLRDEVSGNNLYVYYIETKKNIADVMTKPLPIKTFKLLTNKWIH"
gene 811738..813054
/locus_tag="YGR161W-A"
/db_xref="GeneID:853066"
mRNA <811738..>813054
/locus_tag="YGR161W-A"
/transcript_id="NM_001184401.1"
/db_xref="GI:296145192"
/db_xref="GeneID:853066"
CDS 811738..813054
/locus_tag="YGR161W-A"
/note="Retrotransposon TYA Gag gene co-transcribed with
TYB Pol; translated as TYA or TYA-TYB polyprotein; Gag is
a nucleocapsid protein that is the structural constituent
of virus-like particles (VLPs); similar to retroviral Gag"
/codon_start=1
/product="gag protein"
/protein_id="NP_058164.1"
/db_xref="GI:7839175"
/db_xref="SGD:S000007369"
/db_xref="GeneID:853066"
/translation="MESQQLHQNPHSLHGSAYASVTSKEVPSNQDPLAVSASNLPEFD
RDSTKVNSQQETTPGTSAVPENHHHVSPQPASVPPPQNGQYQQHGMMTPNKAMASNWA
HYQQPSMMTCSHYQTSPAYYQPDPHYPLPQYIPPLSTSSPDPIDSQNQHSEVPQAETK
VRNNVLPPHTLTSEENFSTWVKFYIRFLKNSNLGDIIPNDQGEIKSQMTYEEHAYIYN
TFQAFAPFHLLPTWVKQILEINYADILTVLCKSVSKMQTNNQELKDWIALANLEYDGS
TSADTFEITVSTIIQRLKENNINVSDRLACQLILKGLSGDFKYLRNQYRTKTNMKLSQ
LFAEIQLIYDENKIMNLNKPSQYKQHSEYKNVSRTSPNTTNTKVTTRNYHRTNSSKPR
AAKAHNIATSSKFSRVNNDHINESTVSSQYLSDDNELSLRPATERI"
LTR 817074..817397
/note="Ty2 LTR"
/db_xref="SGD:S000006975"
mobile_element complement(817393..823306)
/note="YGRCTy1-3; Ty1 element, LTR retrotransposon of the
Copia (Pseudoviridae) group; contains co-transcribed genes
TYA Gag and TYB Pol, encoding proteins involved in
structure and function of virus-like particles, flanked by
two direct repeats"
/mobile_element_type="retrotransposon:YGRCTy1-3"
/db_xref="SGD:S000006963"
LTR complement(817393..817724)
/note="Ty1 LTR"
/db_xref="SGD:S000006959"
gene complement(817747..823015)
/locus_tag="YGR161C-D"
/db_xref="GeneID:853068"
mRNA complement(join(<817747..821709,821711..>823015))
/locus_tag="YGR161C-D"
/transcript_id="NM_001184400.3"
/db_xref="GI:398365960"
/db_xref="GeneID:853068"
CDS complement(join(817747..821709,821711..823015))
/locus_tag="YGR161C-D"
/EC_number="2.7.7.49"
/EC_number="3.4.23.-"
/EC_number="3.1.26.4"
/EC_number="2.7.7.7"
/ribosomal_slippage
/note="Retrotransposon TYA Gag and TYB Pol genes;
transcribed/translated as one unit; polyprotein is
processed to make a nucleocapsid-like protein (Gag),
reverse transcriptase (RT), protease (PR), and integrase
(IN); similar to retroviral genes"
/codon_start=1
/product="gag-pol fusion protein"
/protein_id="NP_058165.3"
/db_xref="GI:398365961"
/db_xref="SGD:S000007368"
/db_xref="GeneID:853068"
/translation="MESQQLSNYPHISHGSACASVTSKEVHTNQDPLDVSASKIQEYD
KASTKANSQQTTTPASSAVPENPHHASPQPASVPPPQNGPYPQQCMMTQNQANPSGWS
FYGHPSMIPYTPYQMSPMYFPPGPQSQFPQYPSSVGTPLSTPSPESGNTFTDSSSADS
DMTSTKKYVRPPPMLTSPNDFPNWVKTYIKFLQNSNLGGIIPTVNGKPVRQITDDELT
FLYNTFQIFAPSQFLPTWVKDILSVDYTDIMKILSKSIEKMQSDTQEANDIVTLANLQ
YNGSTPADAFETKVTNIIDRLNNNGIHINNKVACQLIMRGLSGEYKFLRYTRHRHLNM
TVAELFLDIHAIYEEQQGSRNSKPNYRRNPSDEKNDSRSYTNTTKPKVIARNPQKTNN
SKSKTARAHNVSTSNNSPSTDNDSISKSTTEPIQLNNKHDLHLGQKLTESTVNHTNHS
DDELPGHLLLDSGASRTLIRSAHHIHSASSNPDINVVDAQKRNIPINAIGDLQFHFQD
NTKTSIKVLHTPNIAYDLLSLNELAAVDITACFTKNVLERSDGTVLAPIVKYGDFYWV
SKKYLLPSNISVPTINNVHTSESTRKYPYPFIHRMLAHANAQTIRYSLKNNTITYFNE
SDVDWSSAIDYQCPDCLIGKSTKHRHIKGSRLKYQNSYEPFQYLHTDIFGPVHNLPKS
APSYFISFTDETTKFRWVYPLHDRREDSILDVFTTILAFIKNQFQASVLVIQMDRGSE
YTNRTLHKFLEKNGITPCYTTTADSRAHGVAERLNRTLLDDCRTQLQCSGLPNHLWFS
AIEFSTIVRNSLASPKSKKSARQHAGLAGLDISTLLPFGQPVIVNDHNPNSKIHPRGI
PGYALHPSRNSYGYIIYLPSLKKTVDTTNYVILQGKESRLDQFNYDALTFDEDLNRLT
ASYHSFIASNEIQESNDLNIESDHDFQSDIELHPEQPRNVLSKAVSPTDSTPPSTHTE
DSKRVSKTNIRAPREVDPNISESNILPSKKRSSTPQISNIESTGSGGMHKLNVPLLAP
MSQSNTHESSYASKSKDFRHSDSYSDNETNHTNVPISSTGGTNNKTVPQTSEQETEKR
IIHRSPSIDTSSSESNSLHHVVPIKTSDTCPKENTEESIIADLPLPDLPPEPPTELSD
SFKELPPINSRQTNSSLGGIGDSNAYTTINSKKRSLEDNETEIKVSRDTWNTKNMRSL
EPPRSKKRIHLIAAVKAVKSIKPIRTTLRYDEAITYNKDIKEKEKYIEAYHKEVNQLL
KMNTWDTDKYYDRKEIDPKRVINSMFIFNRKRDGTHKARFVARGDIQHPDTYDSGMQS
NTVHHYALMTSLSLALDNNYYITQLDISSAYLYADIKEELYIRPPPHLGMNDKLIRLK
KSLYGLKQSGANWYETIKSYLIKQCGMEEVRGWSCVFKNSQVTICLFVDDMILFSKDL
NSNKRIIAKLKMQYDTKIINLGESDDEIQYDILGLEIKYQRGKYMKLGMENSLTEKIP
KLNVPLNPNGRKLGAPGQPGLYINQQELELEEDDYKMKVHEMQKLIGLASYVGYKFRF
DLLYYINTLAQHILFPSKQVLDMTYELIQFIWNTRDKQLIWHKSKPVKPTNKLVVISD
ASYGNQPYYKSQIGNIYLLNGKVIGGKSTKASLTCTSTTEAEIHAISESVPLLNNLSY
LIQELDKKPITKGLLTDSKSTISIIISNNEEKFRNRFFGTKAMRLRDEVSGNHLHVCY
IETKKNIADVMTKPLPIKTFKLLTNKWIH"
gene complement(821693..823015)
/locus_tag="YGR161C-C"
/db_xref="GeneID:853069"
mRNA complement(<821693..>823015)
/locus_tag="YGR161C-C"
/transcript_id="NM_001184399.1"
/db_xref="GI:296145195"
/db_xref="GeneID:853069"
CDS complement(821693..823015)
/locus_tag="YGR161C-C"
/note="Retrotransposon TYA Gag gene co-transcribed with
TYB Pol; translated as TYA or TYA-TYB polyprotein; Gag is
a nucleocapsid protein that is the structural constituent
of virus-like particles (VLPs); similar to retroviral Gag"
/codon_start=1
/product="gag protein"
/protein_id="NP_058166.1"
/db_xref="GI:7839177"
/db_xref="SGD:S000007367"
/db_xref="GeneID:853069"
/translation="MESQQLSNYPHISHGSACASVTSKEVHTNQDPLDVSASKIQEYD
KASTKANSQQTTTPASSAVPENPHHASPQPASVPPPQNGPYPQQCMMTQNQANPSGWS
FYGHPSMIPYTPYQMSPMYFPPGPQSQFPQYPSSVGTPLSTPSPESGNTFTDSSSADS
DMTSTKKYVRPPPMLTSPNDFPNWVKTYIKFLQNSNLGGIIPTVNGKPVRQITDDELT
FLYNTFQIFAPSQFLPTWVKDILSVDYTDIMKILSKSIEKMQSDTQEANDIVTLANLQ
YNGSTPADAFETKVTNIIDRLNNNGIHINNKVACQLIMRGLSGEYKFLRYTRHRHLNM
TVAELFLDIHAIYEEQQGSRNSKPNYRRNPSDEKNDSRSYTNTTKPKVIARNPQKTNN
SKSKTARAHNVSTSNNSPSTDNDSISKSTTEPIQLNNKHDLHLRPETY"
LTR complement(822975..823306)
/note="Ty1 LTR"
/db_xref="SGD:S000006960"
gene 823482..823555
/locus_tag="tV(AAC)G2"
/db_xref="GeneID:853070"
tRNA 823482..823555
/locus_tag="tV(AAC)G2"
/product="tRNA-Val"
/note="Valine tRNA (tRNA-Val), predicted by tRNAscan-SE
analysis"
/db_xref="SGD:S000006756"
/db_xref="GeneID:853070"
gene 824059..826917
/gene="TIF4631"
/locus_tag="YGR162W"
/db_xref="GeneID:853071"
mRNA 824059..826917
/gene="TIF4631"
/locus_tag="YGR162W"
/product="Tif4631p"
/transcript_id="NM_001181291.3"
/db_xref="GI:398365972"
/db_xref="GeneID:853071"
CDS 824059..826917
/gene="TIF4631"
/locus_tag="YGR162W"
/note="Translation initiation factor eIF4G; subunit of the
mRNA cap-binding protein complex (eIF4F) that also
contains eIF4E (Cdc33p); interacts with Pab1p and with
eIF4A (Tif1p); also has a role in biogenesis of the large
ribosomal subunit; TIF4631 has a paralog, TIF4632, that
arose from the whole genome duplication"
/codon_start=1
/product="Tif4631p"
/protein_id="NP_011678.3"
/db_xref="GI:398365973"
/db_xref="SGD:S000003394"
/db_xref="GeneID:853071"
/translation="MTDETAHPTQSASKQESAALKQTGDDQQESQQQRGYTNYNNGSN
YTQKKPYNSNRPHQQRGGKFGPNRYNNRGNYNGGGSFRGGHMGANSSNVPWTGYYNNY
PVYYQPQQMAAAGSAPANPIPVEEKSPVPTKIEITTKSGEHLDLKEQHKAKLQSQERS
TVSPQPESKLKETSDSTSTSTPTPTPSTNDSKASSEENISEAEKTRRNFIEQVKLRKA
ALEKKRKEQLEGSSGNNNIPMKTTPENVEEKGSDKPEVTEKTKPAEEKSAEPEVKQET
PAEEGEQGEKGQIKEESTPKVLTFAERLKLKKQQKEREEKTEGKENKEVPVQEETKSA
IESAPVPPSEQVKEETEVAETEQSNIDESATTPAIPTKSDEAEAEVEAEAGDAGTKIG
LEAEIETTTDETDDGTNTVSHILNVLKDATPIEDVFSFNYPEGIEGPDIKYKKEHVKY
TYGPTFLLQFKDKLNVKADAEWVQSTASKIVIPPGMGRGNRSRDSGRFGNNSSRGHDF
RNTSVRNMDDRANSRTSSKRRSKRMNDDRRSNRSYTSRRDRERGSYRNEEKREDDKPK
EEVAPLVPSANRWVPKFKSKKTEKKLAPDGKTELLDKDEVERKMKSLLNKLTLEMFDA
ISSEILAIANISVWETNGETLKAVIEQIFLKACDEPHWSSMYAQLCGKVVKELNPDIT
DETNEGKTGPKLVLHYLVARCHAEFDKGWTDKLPTNEDGTPLEPEMMSEEYYAAASAK
RRGLGLVRFIGFLYRLNLLTGKMMFECFRRLMKDLTDSPSEETLESVVELLNTVGEQF
ETDSFRTGQATLEGSQLLDSLFGILDNIIQTAKISSRIKFKLIDIKELRHDKNWNSDK
KDNGPKTIQQIHEEEERQRQLKNNSRSNSRRTNNSSNRHSFRRDAPPASKDSFITTRT
YSQRNSQRAPPPKEEPAAPTSTATNMFSALMGESDDEE"
gene 827552..828577
/gene="GTR2"
/locus_tag="YGR163W"
/db_xref="GeneID:853072"
mRNA 827552..828577
/gene="GTR2"
/locus_tag="YGR163W"
/product="Gtr2p"
/transcript_id="NM_001181292.3"
/db_xref="GI:398365978"
/db_xref="GeneID:853072"
CDS 827552..828577
/gene="GTR2"
/locus_tag="YGR163W"
/note="Putative GTP binding protein that negatively
regulates Ran/Tc4 GTPase cycle; activates transcription;
subunit of EGO and GSE complexes; required for sorting of
Gap1p; localizes to cytoplasm and to chromatin; homolog of
human RagC and RagD"
/codon_start=1
/product="Gtr2p"
/protein_id="NP_011679.3"
/db_xref="GI:398365979"
/db_xref="SGD:S000003395"
/db_xref="GeneID:853072"
/translation="MSLEATDSKAMVLLMGVRRCGKSSICKVVFHNMQPLDTLYLEST
SNPSLEHFSTLIDLAVMELPGQLNYFEPSYDSERLFKSVGALVYVIDSQDEYINAITN
LAMIIEYAYKVNPSINIEVLIHKVDGLSEDFKVDAQRDIMQRTGEELLELGLDGVQVS
FYLTSIFDHSIYEAFSRIVQKLIPELSFLENMLDNLIQHSKIEKAFLFDVNSKIYVST
DSNPVDIQMYEVCSEFIDVTIDLFDLYKAPVLRNSQKSSDKDNVINPRNELQNVSQLA
NGVIIYLRQMIRGLALVAIIRPNGTDMESCLTVADYNIDIFKKGLEDIWANARASQAK
NSIEDDV"
gene complement(828723..828794)
/locus_tag="tR(UCU)G2"
/db_xref="GeneID:853074"
tRNA complement(828723..828794)
/locus_tag="tR(UCU)G2"
/product="tRNA-Arg"
/note="Arginine tRNA (tRNA-Arg), predicted by tRNAscan-SE
analysis; one of 11 nuclear tRNA genes containing the
tDNA-anticodon UCU (converted to mcm5-UCU in the mature
tRNA), decodes AGA codons into arginine, one of 19 nuclear
tRNAs for arginine"
/db_xref="SGD:S000006712"
/db_xref="GeneID:853074"
gene 829116..830153
/gene="MRPS35"
/locus_tag="YGR165W"
/db_xref="GeneID:853075"
mRNA 829116..830153
/gene="MRPS35"
/locus_tag="YGR165W"
/product="mitochondrial 37S ribosomal protein MRPS35"
/transcript_id="NM_001181294.1"
/db_xref="GI:296145198"
/db_xref="GeneID:853075"
CDS 829116..830153
/gene="MRPS35"
/locus_tag="YGR165W"
/note="Mitochondrial ribosomal protein of the small
subunit; null mutant does not grow on glycerol, is
sensitive to 2,4-dichlorophenol, and accumulates large
lipid droplets"
/codon_start=1
/product="mitochondrial 37S ribosomal protein MRPS35"
/protein_id="NP_011681.1"
/db_xref="GI:6321604"
/db_xref="SGD:S000003397"
/db_xref="GeneID:853075"
/translation="MSYGLTGTSSKLRGTSSIFSWTQVRHFSRRRIAYPFYPFKKLGR
QHPKKHDTNLKTAMRQFLGPKNYKGEYVMNKYFTVPTNHVPNYIKPDLERGQSLEHPV
TKKPLQLRYDGTLGPPPVENKRLQNIFKDRLLQPFPSNPHCKTNYVLSPQLKQSIFEE
ITVEGLSAQQVSQKYGLKIPRVEAIVKLVSVENSWNRRNRVSSDLKTMDETLYRMFPV
FDSDASFKRENLSEIPVPQKTLASRFLTIAESEPFGPVDAAHVLELEPAVETLRNLST
VGEHSSGHQQSTNKNTKVIYGELVEGERSQYKFTNAKVGKVGYRYGSGNRDNKKDRRI
GFNKLGQMVYI"
gene 830515..832197
/gene="TRS65"
/locus_tag="YGR166W"
/gene_synonym="KRE11"
/db_xref="GeneID:853076"
mRNA 830515..832197
/gene="TRS65"
/locus_tag="YGR166W"
/gene_synonym="KRE11"
/product="Trs65p"
/transcript_id="NM_001181295.1"
/db_xref="GI:296145199"
/db_xref="GeneID:853076"
CDS 830515..832197
/gene="TRS65"
/locus_tag="YGR166W"
/gene_synonym="KRE11"
/note="Subunit of TRAPPII, a multimeric guanine
nucleotide-exchange factor for Ypt1p; involved in
intra-Golgi traffic and the retrograde pathway from the
endosome to Golgi; role in cell wall beta-glucan
biosynthesis and the stress response"
/codon_start=1
/product="Trs65p"
/protein_id="NP_011682.1"
/db_xref="GI:6321605"
/db_xref="SGD:S000003398"
/db_xref="GeneID:853076"
/translation="MECFVPLRCDLDGSNIEQLRQSHLSRKFIIFDEQLNLWLWFQGN
SQENKRFVLQNMIILINEAQVTRTSTIDDYFTQVENNENLWRLKNDCCSKILFKSNVV
MNNGYNNQIKFVFEYKSVDANFNNQDSLQDPQAKYTLDKYSSEEILPSFEPVYSWSSA
ATKSSKNTNNHLEKNNRATHRVSSKNSEVHEADVSRNPNTFTLKLQYPIFSLLNMRLR
NISLKSEHCILSSLDFQTSKASEQLTKKFIYPQEHNSFLKLNFQEISYKLIDGTSQIE
LDPICPLKVPLTAFSYDSISATFKLVLLPKSTQPHRVKITLAYELELHPNLKLPVRTS
WETEVTLKRSMPISSTSSQYSSNNNNTNHSASFNGAANNVNSGGLANLRLGGVSSSRF
SLGAASTTSLVNSKLSNVKFKFINSNIKVIKGEKFTMRLQIINSSSSPLDLVVYYNNT
INPIPSANNVRNSNGINNCGMNNGTIPNSPLTLENQYQLHNKYRKIAEGIILLSNDYK
IPVVPPRETYFADLRFIGIMSGYYGTLSGLKVLDLNTNELIEVGNGASVLIQ"
gene 832456..833157
/gene="CLC1"
/locus_tag="YGR167W"
/gene_synonym="SCD4"
/db_xref="GeneID:853077"
mRNA 832456..833157
/gene="CLC1"
/locus_tag="YGR167W"
/gene_synonym="SCD4"
/product="Clc1p"
/transcript_id="NM_001181296.3"
/db_xref="GI:398365990"
/db_xref="GeneID:853077"
CDS 832456..833157
/gene="CLC1"
/locus_tag="YGR167W"
/gene_synonym="SCD4"
/note="Clathrin light chain; subunit of the major coat
protein involved in intracellular protein transport and
endocytosis; thought to regulate clathrin function; two
Clathrin heavy chains (CHC1) form the clathrin triskelion
structural component; YGR167W"
/codon_start=1
/product="Clc1p"
/protein_id="NP_011683.3"
/db_xref="GI:398365991"
/db_xref="SGD:S000003399"
/db_xref="GeneID:853077"
/translation="MSEKFPPLEDQNIDFTPNDKKDDDTDFLKREAEILGDEFKTEQD
DILETEASPAKDDDEIRDFEEQFPDINSANGAVSSDQNGSATVSSGNDNGEADDDFST
FEGANQSTESVKEDRSEVVDQWKQRRAVEIHEKDLKDEELKKELQDEAIKHIDDFYDS
YNKKKEQQLEDAAKEAEAFLKKRDEFFGQDNTTWDRALQLINQDDADIIGGRDRSKLK
EILLRLKGNAKAPGA"
gene complement(833352..834482)
/locus_tag="YGR168C"
/db_xref="GeneID:853078"
mRNA complement(833352..834482)
/locus_tag="YGR168C"
/product="hypothetical protein"
/transcript_id="NM_001181297.1"
/db_xref="GI:296145201"
/db_xref="GeneID:853078"
CDS complement(833352..834482)
/locus_tag="YGR168C"
/note="hypothetical protein; YGR168C is not an essential
gene"
/codon_start=1
/product="hypothetical protein"
/protein_id="NP_011684.1"
/db_xref="GI:6321607"
/db_xref="SGD:S000003400"
/db_xref="GeneID:853078"
/translation="MKHNRPNGTGKAVSGFKQIIRRLLLLLNKKRRKQLVIILKRITQ
VYGINLVFYVKKWKLKKLQGENIQINDIMPWLRESTILVLLNILYPTLMKFPFLKNHY
IHWSSIVGISLMLTKGEVPSWIIAHFLVEAIASKLKIAKLTQWLKKKNFSQGTLIKFQ
QILVCLAIIVLFAKLDRSSLPFRVLFDHRPFLIDFFTINAIFTVLAVYHRTLKFFFTS
GTKSNKNVGGHEVRNFSQYLGVKNHNDWPISSSNLKHVMDRLNEIHEVTIDDNYANIN
EKIINSYFTKGFFPSLKWTILRQCIEYLFVTKRRRLMGNKLRCIVMLLTFTFVDPTSK
MKISPFFAKFFAKSLVNVYLKKYWHCNFGKYILFFLFQLSIM"
rep_origin 834491..834734
/note="ARS731;
Autonomously Replicating Sequence"
/db_xref="SGD:S000118466"
gene complement(834689..835903)
/gene="PUS6"
/locus_tag="YGR169C"
/db_xref="GeneID:853079"
mRNA complement(834689..835903)
/gene="PUS6"
/locus_tag="YGR169C"
/product="pseudouridine synthase PUS6"
/transcript_id="NM_001181298.3"
/db_xref="GI:398366002"
/db_xref="GeneID:853079"
CDS complement(834689..835903)
/gene="PUS6"
/locus_tag="YGR169C"
/EC_number="5.4.99.-"
/note="tRNA:pseudouridine synthase, catalyzes the
conversion of uridine to pseudouridine at position 31 in
cytoplasmic and mitochondrial tRNAs; mutation of Asp168 to
Ala abolishes enzyme activity; not essential for
viability"
/codon_start=1
/product="pseudouridine synthase PUS6"
/protein_id="NP_011685.3"
/db_xref="GI:398366003"
/db_xref="SGD:S000003401"
/db_xref="GeneID:853079"
/translation="MSTIKVIEVYTQNGLRKVRPYYNRRSAFVKGRWLGKLLIDVLVS
EFKLRPRAYYLDQIRKGTYRLIRDGVPLVPDHLMTTIIKNHDVLETTTHKHEPPVKQW
CSQEVEAEDLPGRIAGFNIVFEDESILVIDKPSGIPVHPTGQFYQNTITELLKLHGVD
ALPCYRLDKITSGLLILAKNSQSAGEIQKSIRSRDMIKIYLARVKGRFPHSELILDNE
NAAETTFEDTSKVTVEMTPIYSIDPKRQFPVGLSTSKDAITKFYPIRYFSHADETVVA
CKPITGRTHQIRIHLARLGHPIVNDSVYCSHITKYPERLKFITQFPRWENQQDLDAEE
LKVRFQKFVDETKNNCRTMETFCPECHTVDLKDPVLSDLELWLHAWKYEEINGKFKFK
TDLPKWAQLDNS"
gene complement(836387..836665)
/locus_tag="YGR169C-A"
/gene_synonym="YGR169C-C"
/db_xref="GeneID:1466460"
mRNA complement(836387..836665)
/locus_tag="YGR169C-A"
/gene_synonym="YGR169C-C"
/product="hypothetical protein"
/transcript_id="NM_001184531.3"
/db_xref="GI:398366008"
/db_xref="GeneID:1466460"
CDS complement(836387..836665)
/locus_tag="YGR169C-A"
/gene_synonym="YGR169C-C"
/codon_start=1
/product="hypothetical protein"
/protein_id="NP_878080.3"
/db_xref="GI:398366009"
/db_xref="SGD:S000028521"
/db_xref="GeneID:1466460"
/translation="MGKRFSESAAKKAAGLARKRDQAHAKQRAQMEQLEAEEASKWEQ
GSRKENAKKLEEEQKRQEKARAKKERDALLTAEEEQLGKGGKGKRKMK"
gene 837142..840558
/gene="PSD2"
/locus_tag="YGR170W"
/db_xref="GeneID:853080"
mRNA 837142..840558
/gene="PSD2"
/locus_tag="YGR170W"
/product="phosphatidylserine decarboxylase 2"
/transcript_id="NM_001181299.1"
/db_xref="GI:296145204"
/db_xref="GeneID:853080"
CDS 837142..840558
/gene="PSD2"
/locus_tag="YGR170W"
/EC_number="4.1.1.65"
/note="Phosphatidylserine decarboxylase of the Golgi and
vacuolar membranes, converts phosphatidylserine to
phosphatidylethanolamine"
/codon_start=1
/product="phosphatidylserine decarboxylase 2"
/protein_id="NP_011686.1"
/db_xref="GI:6321609"
/db_xref="SGD:S000003402"
/db_xref="GeneID:853080"
/translation="MRIIKGRKRGKNKKPTLILKIHVIQAENIEALKTFNCNPVCFVT
TNTFYSQKTNKLKNSNTHWNQTLRIKLPRNPTSEWLRIIVYDALPTGAPPTTPSRPRT
TTANTSSSTLSNSGLSSHSHSSRNLNVTSKGNQTSTSINSVSSSATPAPSHSSSSLST
TGPGSTHKNRINSYLYLGEAKISLLDLFKRKDTTTSYKFSIEAQRYHLYDMKGGKDQD
SLNCNFLVGDILLGFKLECNVKRTPTFQAFNAWRNELNTYLGRIDRNKARMRSSSSLP
PPLEDMLSNSSAVSGNEIRREKPYSDTDLAHDEEVNAEDEIDAEESIEDMNSSGSICT
ERRYDIDNDTIFDSISEVVSLNDEELDILNDFEEADHPNVPDINVHDIDEDTRISLSS
MITALDEYDIVEPEDVAKLPAVSENDITSVDDEESENQQESDEEFDIYNEDEREDSDF
QSKEYIGSRLLHLQRGKHNKSYANYLYRRAKSNFFISKKEHAMGVVFMHIGAIKNLPA
LRNRLSKTNYEMDPFIVISFGRRVFKTSWRKHTLNPEFNEYAAFEVFPHETNFAFSIK
VVDKDSFSFNDDVAKCELAWFDMLQQQQHENEWIPYEIPLDLTVEPAHAPKQPVLYSS
FKYVSYPFLKKSFWKEAVDTSVNLERLDIIQVMLYLERLGSFTMADSFELFQHFNKSA
WAGQSITRSQLVEGLQSWRKSTNFKRIWTCPRCMRSCKPTRNARRSKLVLENDLITHF
AICTFSKEHKTLKPSYVSSAFASKRWFSKVLIKLTYGKYALGSNNANILVQDRDTGII
IEEKISAHVKLGMRIIYNGKSPESKKFRSLLKTLSIRQGKKFDSTASAKQIEPFIKFH
SLDLSQCRDKDFKTFNEFFYRKLKPGSRLPESNNKEILFSPADSRCTVFPTIQESKEI
WVKGRKFSIKKLANNYNPETFNDNNCSIGIFRLAPQDYHRFHSPCNGTIGKPVYVDGE
YYTVNPMAVRSELDVFGENIRVIIPIDSPQFGKLLYIPIGAMMVGSILLTCKENDVVE
SGQELGYFKFGGSTIIIIIPHNNFMFDSDLVKNSSERIETLVKVGMSIGHTSNVNELK
RIRIKVDDPKKIERIKRTISVSDENAKSTGNVTWEYHTLREMMNKDFAGL"
gene complement(840824..842551)
/gene="MSM1"
/locus_tag="YGR171C"
/db_xref="GeneID:853081"
mRNA complement(840824..842551)
/gene="MSM1"
/locus_tag="YGR171C"
/product="methionine--tRNA ligase MSM1"
/transcript_id="NM_001181300.1"
/db_xref="GI:296145205"
/db_xref="GeneID:853081"
CDS complement(840824..842551)
/gene="MSM1"
/locus_tag="YGR171C"
/EC_number="6.1.1.10"
/note="Mitochondrial methionyl-tRNA synthetase (MetRS),
functions as a monomer in mitochondrial protein synthesis;
functions similarly to cytoplasmic MetRS although the
cytoplasmic form contains a zinc-binding domain not found
in Msm1p"
/codon_start=1
/product="methionine--tRNA ligase MSM1"
/protein_id="NP_011687.1"
/db_xref="GI:6321610"
/db_xref="SGD:S000003403"
/db_xref="GeneID:853081"
/translation="MQCRSIVHRLYSKVSHVTTPIFYPNAKPHLGHLYSSLLSDVYHR
WQLFKGNLSFFTTGTDEHGLKIQCASESNGFDQPKKFVDKLYPEFVQLDKIYGINYTR
FIRTTDPDHIENVMKLWELCLKNGYIYMGEHKGWYSISDETFYPESKVIKDPKNDGKY
LNTESKNEVVYQSETNYFFRLSLFNKKIVDHIRKNPDFIFPASKRDQILKELETGGTL
PDLSISRPSARLKWGIPTPNDPSQKVYVWFDALCNYLSSIGGIPSILSNATEVVSRHY
SDKSNVKGQLLIPYPKEVQRNTIHVIGKDIAKFHTVYWPSFLLAAGLPLPRQIVVHGH
WLCNGMKMSKSLGNVVDPIDMARYYGADIVRWFLLENSKLEEDGDFQEAKLYETRELL
VSKWGNLINRCCGSKFNIERAVMKFSDKANFQFQEIFQNEPIVSERIENLAKLLNKSQ
EVFDEKIAIFQYPQLLRHVWSIINDANTLVQNSKPWERELDQQDNIIFLAMETSRILS
ILCQSIIPSLSQSFLDRIDVSKEKRTINYARLGSDKTYGKQSNKKGREVPLKKIPFRL
QEEQTNMRS"
gene complement(842845..843591)
/gene="YIP1"
/locus_tag="YGR172C"
/db_xref="GeneID:853082"
mRNA complement(842845..843591)
/gene="YIP1"
/locus_tag="YGR172C"
/product="Yip1p"
/transcript_id="NM_001181301.3"
/db_xref="GI:398366018"
/db_xref="GeneID:853082"
CDS complement(842845..843591)
/gene="YIP1"
/locus_tag="YGR172C"
/note="Integral membrane protein required for the
biogenesis of ER-derived COPII transport vesicles;
interacts with Yif1p and Yos1p; localizes to the Golgi,
the ER, and COPII vesicles; homolog of human YIPF4"
/codon_start=1
/product="Yip1p"
/protein_id="NP_011688.3"
/db_xref="GI:398366019"
/db_xref="SGD:S000003404"
/db_xref="GeneID:853082"
/translation="MSFYNTSNNANNGGGFYQPSAQFAVPQGSMSFQNTVGSSNTGND
NNLGVAPDPLPVGILHALSTKGYPHEPPLLEEIGINFDHIITKTKMVLIPIRFGSGVP
QEILNDSDLAGPLIFFLLFGLFLLMAGKVHFGYIYGVALFGTISLHNLSKLMSNNDTS
TQTNLQFFNTASILGYCFLPLCFLSLLGIFHGLNNTTGYVVSVLFVIWSTWTSSGFLN
SLLQLQNARLLIAYPLLIFYSVFALMVIFV"
gene 843854..844960
/gene="RBG2"
/locus_tag="YGR173W"
/gene_synonym="GIR1"
/db_xref="GeneID:853083"
mRNA 843854..844960
/gene="RBG2"
/locus_tag="YGR173W"
/gene_synonym="GIR1"
/product="Rbg2p"
/transcript_id="NM_001181302.1"
/db_xref="GI:296145207"
/db_xref="GeneID:853083"
CDS 843854..844960
/gene="RBG2"
/locus_tag="YGR173W"
/gene_synonym="GIR1"
/note="Protein with a role in translation; forms a complex
with Gir2p; has similarity to mammalian developmentally
regulated GTP-binding protein"
/codon_start=1
/product="Rbg2p"
/protein_id="NP_011689.1"
/db_xref="GI:6321612"
/db_xref="SGD:S000003405"
/db_xref="GeneID:853083"
/translation="MGIIDKIKAIEEEMARTQKNKATEHHLGLLKGKLARYRQQLLAD
EAGSGGGGGSGFEVAKSGDARVVLIGYPSVGKSSLLGKITTTKSEIAHYAFTTLTSVP
GVLKYQGAEIQIVDLPGIIYGASQGKGRGRQVVATARTADLVLMVLDATKSEHQRASL
EKELENVGIRLNKEKPNIYYKKKETGGVKVTFTSPPKTNLTEQAIKMILRDYRIHNAE
VLVRDDQCTIDDFIDVINEQHRNYVKCLYVYNKIDAVSLEEVDKLAREPNTVVMSCEM
DLGLQDVVEEIWYQLNLSRVYTKKRGVRPVFDDPLVVRNNSTIGDLCHGIHRDFKDKF
KYALVWGSSAKHSPQKCGLNHRIDDEDVVSLFAK"
LTR 845281..845602
/note="Ty3 LTR"
/db_xref="SGD:S000006981"
gene 845649..845719
/locus_tag="tG(GCC)G1"
/db_xref="GeneID:853084"
tRNA 845649..845719
/locus_tag="tG(GCC)G1"
/product="tRNA-Gly"
/note="Glycine tRNA (tRNA-Gly), predicted by tRNAscan-SE
analysis"
/db_xref="SGD:S000006581"
/db_xref="GeneID:853084"
gene complement(845893..846405)
/gene="CBP4"
/locus_tag="YGR174C"
/db_xref="GeneID:853085"
mRNA complement(845893..846405)
/gene="CBP4"
/locus_tag="YGR174C"
/product="Cbp4p"
/transcript_id="NM_001181303.3"
/db_xref="GI:398366024"
/db_xref="GeneID:853085"
CDS complement(845893..846405)
/gene="CBP4"
/locus_tag="YGR174C"
/note="Mitochondrial protein required for assembly of
cytochrome bc1 complex; interacts with the Cbp3p-Cbp6p
complex and newly synthesized cytochrome b (Cobp) to
promote assembly of Cobp into the cytochrome bc1 complex"
/codon_start=1
/product="Cbp4p"
/protein_id="NP_011690.3"
/db_xref="GI:398366025"
/db_xref="SGD:S000003406"
/db_xref="GeneID:853085"
/translation="MQCAITPREAVIAKQRQYKHYLGMERPLWVRWLKVYAIGGAIIG
SGFLLFKYTTPTDQQLISQLSPELRLQYEREKKLRQSEQQALMKIVKETSQSDDPIWK
TGPLQSPWERNGDNVQSRDHFAKVRAEEVQKEELARIRNELSQLRSETEEKTKEIVQD
KQVKSWWRFW"
gene 846655..846741
/locus_tag="YGR174W-A"
/db_xref="GeneID:1466461"
mRNA 846655..846741
/locus_tag="YGR174W-A"
/product="hypothetical protein"
/transcript_id="NM_001184595.3"
/db_xref="GI:398366030"
/db_xref="GeneID:1466461"
CDS 846655..846741
/locus_tag="YGR174W-A"
/note="hypothetical protein; predicted to have a role in
cell budding based on computational 'guilt by association'
analysis"
/codon_start=1
/product="hypothetical protein"
/protein_id="NP_878081.3"
/db_xref="GI:398366031"
/db_xref="SGD:S000028639"
/db_xref="GeneID:1466461"
/translation="MNLNAYFEAYQAIFPFLLEAFLRKEQKV"
gene complement(846933..848423)
/gene="ERG1"
/locus_tag="YGR175C"
/db_xref="GeneID:853086"
mRNA complement(846933..848423)
/gene="ERG1"
/locus_tag="YGR175C"
/product="squalene monooxygenase"
/transcript_id="NM_001181304.1"
/db_xref="GI:296145210"
/db_xref="GeneID:853086"
CDS complement(846933..848423)
/gene="ERG1"
/locus_tag="YGR175C"
/EC_number="1.14.13.132"
/note="Squalene epoxidase, catalyzes the epoxidation of
squalene to 2,3-oxidosqualene; plays an essential role in
the ergosterol-biosynthesis pathway and is the specific
target of the antifungal drug terbinafine"
/codon_start=1
/product="squalene monooxygenase"
/protein_id="NP_011691.1"
/db_xref="GI:6321614"
/db_xref="SGD:S000003407"
/db_xref="GeneID:853086"
/translation="MSAVNVAPELINADNTITYDAIVIGAGVIGPCVATGLARKGKKV
LIVERDWAMPDRIVGELMQPGGVRALRSLGMIQSINNIEAYPVTGYTVFFNGEQVDIP
YPYKADIPKVEKLKDLVKDGNDKVLEDSTIHIKDYEDDERERGVAFVHGRFLNNLRNI
TAQEPNVTRVQGNCIEILKDEKNEVVGAKVDIDGRGKVEFKAHLTFICDGIFSRFRKE
LHPDHVPTVGSSFVGMSLFNAKNPAPMHGHVILGSDHMPILVYQISPEETRILCAYNS
PKVPADIKSWMIKDVQPFIPKSLRPSFDEAVSQGKFRAMPNSYLPARQNDVTGMCVIG
DALNMRHPLTGGGMTVGLHDVVLLIKKIGDLDFSDREKVLDELLDYHFERKSYDSVIN
VLSVALYSLFAADSDNLKALQKGCFKYFQRGGDCVNKPVEFLSGVLPKPLQLTRVFFA
VAFYTIYLNMEERGFLGLPMALLEGIMILITAIRVFTPFLFGELIG"
gene complement(848829..850436)
/gene="ATF2"
/locus_tag="YGR177C"
/db_xref="GeneID:853088"
mRNA complement(848829..850436)
/gene="ATF2"
/locus_tag="YGR177C"
/product="Atf2p"
/transcript_id="NM_001181306.1"
/db_xref="GI:296145211"
/db_xref="GeneID:853088"
CDS complement(848829..850436)
/gene="ATF2"
/locus_tag="YGR177C"
/EC_number="2.3.1.84"
/note="Alcohol acetyltransferase, may play a role in
steroid detoxification; forms volatile esters during
fermentation, which is important for brewing and
winemaking"
/codon_start=1
/product="Atf2p"
/protein_id="NP_011693.1"
/db_xref="GI:6321616"
/db_xref="SGD:S000003409"
/db_xref="GeneID:853088"
/translation="MEDIEGYEPHITQELIDRGHARRMGHLENYFAVLSRQKMYSNFT
VYAELNKGVNKRQLMLVLKVLLQKYSTLAHTIIPKHYPHHEAYYSSEEYLSKPFPQHD
FIKVISHLEFDDLIMNNQPEYREVMEKISEQFKKDDFKVTNRLIELISPVIIPLGNPK
RPNWRLICLPGKDTDGFETWKNFVYVTNHCGSDGVSGSNFFKDLALLFCKIEEKGFDY
DEEFIEDQVIIDYDRDYTEISKLPKPITDRIDYKPALTSLPKFFLTTFIYEHCNFKTS
SESTLTARYSPSSNANASYNYLLHFSTKQVEQIRAQIKKNVHDGCTLTPFIQACFLVA
LYRLDKLFTKSLLEYGFDVAIPSNARRFLPNDEELRDSYKYGSNVGGSHYAYLISSFD
IPEGDNDKFWSLVEYYYDRFLESYDNGDHLIGLGVLQLDFIVENKNIDSLLANSYLHQ
QRGGAIISNTGLVSQDTTKPYYVRDLIFSQSAGALRFAFGLNVCSTNVNGMNMDMSVV
QGTLRDRGEWESFCKLFYQTIGEFASL"
gene complement(851047..853215)
/gene="PBP1"
/locus_tag="YGR178C"
/gene_synonym="MRS16"
/db_xref="GeneID:853089"
mRNA complement(851047..853215)
/gene="PBP1"
/locus_tag="YGR178C"
/gene_synonym="MRS16"
/product="Pbp1p"
/transcript_id="NM_001181307.3"
/db_xref="GI:398366038"
/db_xref="GeneID:853089"
CDS complement(851047..853215)
/gene="PBP1"
/locus_tag="YGR178C"
/gene_synonym="MRS16"
/note="Component of glucose deprivation induced stress
granules; involved in P-body-dependent granule assembly;
similar to human ataxin-2; interacts with Pab1p to
regulate mRNA polyadenylation; interacts with Mkt1p to
regulate HO translation; protein increases in abundance
and relative distribution to the nucleus increases upon
DNA replication stress"
/codon_start=1
/product="Pbp1p"
/protein_id="NP_011694.3"
/db_xref="GI:398366039"
/db_xref="SGD:S000003410"
/db_xref="GeneID:853089"
/translation="MKGNFRKRDSSTNSRKGGNSDSNYTNGGVPNQNNSSMFYENPEI
TRNFDDRQDYLLANSIGSDVTVTVTSGVKYTGLLVSCNLESTNGIDVVLRFPRVADSG
VSDSVDDLAKTLGETLLIHGEDVAELELKNIDLSLDEKWENSKAQETTPARTNIEKER
VNGESNEVTKFRTDVDISGSGREIKERKLEKWTPEEGAEHFDINKGKALEDDSASWDQ
FAVNEKKFGVKSTFDEHLYTTKINKDDPNYSKRLQEAERIAKEIESQGTSGNIHIAED
RGIIIDDSGLDEEDLYSGVDRRGDELLAALKSNSKPNSNKGNRYVPPTLRQQPHHMDP
AIISSSNSNKNENAVSTDTSTPAAAGAPEGKPPQKTSKNKKSLSSKEAQIEELKKFSE
KFKVPYDIPKDMLEVLKRSSSTLKSNSSLPPKPISKTPSAKTVSPTTQISAGKSESRR
SGSNISQGQSSTGHTTRSSTSLRRRNHGSFFGAKNPHTNDAKRVLFGKSFNMFIKSKE
AHDEKKKGDDASENMEPFFIEKPYFTAPTWLNTIEESYKTFFPDEDTAIQEAQTRFQQ
RQLNSMGNAVPGMNPAMGMNMGGMMGFPMGGPSASPNPMMNGFAAGSMGMYMPFQPQP
MFYHPSMPQMMPVMGSNGAEEGGGNISPHVPAGFMAAGPGAPMGAFGYPGGIPFQGMM
GSGPSGMPANGSAMHSHGHSRNYHQTSHHGHHNSSTSGHK"
gene complement(853675..854895)
/gene="OKP1"
/locus_tag="YGR179C"
/db_xref="GeneID:853090"
mRNA complement(853675..854895)
/gene="OKP1"
/locus_tag="YGR179C"
/product="Okp1p"
/transcript_id="NM_001181308.1"
/db_xref="GI:296145213"
/db_xref="GeneID:853090"
CDS complement(853675..854895)
/gene="OKP1"
/locus_tag="YGR179C"
/note="Outer kinetochore protein required for accurate
chromosome segregation; component of COMA (Ctf19p, Okp1p,
Mcm21p, Ame1p) a kinetochore sub-complex which functions
as a platform for kinetochore assembly; orthologous to
human centromere constitutive-associated network (CCAN)
subunit CENP-Q and fission yeast fta7"
/codon_start=1
/product="Okp1p"
/protein_id="NP_011695.1"
/db_xref="GI:6321618"
/db_xref="SGD:S000003411"
/db_xref="GeneID:853090"
/translation="MAADRDNFLQNIENDSINNGQAMDLSPNRSSSESDSSILMNVND
IKTLRLDVAPEAKSTQSKKSLFYENSDDAEEGEIEERTNKEEGQYHHKGSKQLRFEVG
KESTGKLQSHLSDGSATSGEGNVRPWEFRKVIQAEYRERLPRNYELKHWKKPSKIMIG
SILRLLETNTVSALDSVFEKYEKEMNQMTHGDNNEVKRIYSKKERLLEIILTKIKKKL
RQAKFPSRISERDLDIEYIYSKRQFIQNRYSQELQNNERLEAILSREQNLLEETRKLC
MNLKTNNKKRLTEKLIQKDLHPVLNKAMEYTYGLESTNGFMHPDGPVTFRNDSHELNL
MLNDPIKSTADVRLDKEEVLSLLPSLKEYTKKSKELKETMGQMISDSHEEEIKEVFVP
HHESHQDKTEEDIH"
gene complement(855264..856301)
/gene="RNR4"
/locus_tag="YGR180C"
/gene_synonym="CRT3; PSO3"
/db_xref="GeneID:853091"
mRNA complement(855264..856301)
/gene="RNR4"
/locus_tag="YGR180C"
/gene_synonym="CRT3; PSO3"
/product="ribonucleotide-diphosphate reductase subunit
RNR4"
/transcript_id="NM_001181309.3"
/db_xref="GI:398366046"
/db_xref="GeneID:853091"
CDS complement(855264..856301)
/gene="RNR4"
/locus_tag="YGR180C"
/gene_synonym="CRT3; PSO3"
/EC_number="1.17.4.1"
/note="Ribonucleotide-diphosphate reductase (RNR) small
subunit; the RNR complex catalyzes the rate-limiting step
in dNTP synthesis and is regulated by DNA replication and
DNA damage checkpoint pathways via localization of the
small subunits; relocalizes from nucleus to cytoplasm upon
DNA replication stress"
/codon_start=1
/product="ribonucleotide-diphosphate reductase subunit
RNR4"
/protein_id="NP_011696.3"
/db_xref="GI:398366047"
/db_xref="SGD:S000003412"
/db_xref="GeneID:853091"
/translation="MEAHNQFLKTFQKERHDMKEAEKDEILLMENSRRFVMFPIKYHE
IWAAYKKVEASFWTAEEIELAKDTEDFQKLTDDQKTYIGNLLALSISSDNLVNKYLIE
NFSAQLQNPEGKSFYGFQIMMENIYSEVYSMMVDAFFKDPKNIPLFKEIANLPEVKHK
AAFIERWISNDDSLYAERLVAFAAKEGIFQAGNYASMFWLTDKKIMPGLAMANRNICR
DRGAYTDFSCLLFAHLRTKPNPKIIEKIITEAVEIEKEYYSNSLPVEKFGMDLKSIHT
YIEFVADGLLQGFGNEKYYNAVNPFEFMEDVATAGKTTFFEKKVSDYQKASDMSKSAT
PSKEINFDDDF"
gene complement(857378..857491)
/locus_tag="tL(CAA)G3"
/db_xref="GeneID:853092"
tRNA complement(join(857378..857421,857454..857491))
/locus_tag="tL(CAA)G3"
/product="tRNA-Leu"
/note="Leucine tRNA (tRNA-Leu), predicted by tRNAscan-SE
analysis"
/db_xref="SGD:S000006641"
/db_xref="GeneID:853092"
gene 858287..858604
/gene="TIM13"
/locus_tag="YGR181W"
/db_xref="GeneID:853093"
mRNA 858287..858604
/gene="TIM13"
/locus_tag="YGR181W"
/product="Tim13p"
/transcript_id="NM_001181310.3"
/db_xref="GI:398366054"
/db_xref="GeneID:853093"
CDS 858287..858604
/gene="TIM13"
/locus_tag="YGR181W"
/note="Mitochondrial intermembrane space protein, forms a
complex with Tim8p that delivers a subset of hydrophobic
proteins to the TIM22 complex for insertion into the inner
membrane"
/codon_start=1
/product="Tim13p"
/protein_id="NP_011697.3"
/db_xref="GI:398366055"
/db_xref="SGD:S000003413"
/db_xref="GeneID:853093"
/translation="MGLSSIFGGGAPSQQKEAATTAKTTPNPIAKELKNQIAQELAVA
NATELVNKISENCFEKCLTSPYATRNDACIDQCLAKYMRSWNVISKAYISRIQNASAS
GEI"
gene complement(859063..859476)
/gene="QCR9"
/locus_tag="YGR183C"
/gene_synonym="UCR9"
/db_xref="GeneID:853095"
mRNA complement(join(859063..859260,859474..859476))
/gene="QCR9"
/locus_tag="YGR183C"
/gene_synonym="UCR9"
/product="ubiquinol--cytochrome-c reductase subunit 9"
/transcript_id="NM_001181312.1"
/db_xref="GI:296145216"
/db_xref="GeneID:853095"
CDS complement(join(859063..859260,859474..859476))
/gene="QCR9"
/locus_tag="YGR183C"
/gene_synonym="UCR9"
/note="Subunit 9 of the ubiquinol cytochrome-c reductase
complex, which is a component of the mitochondrial inner
membrane electron transport chain; required for electron
transfer at the ubiquinol oxidase site of the complex"
/codon_start=1
/product="ubiquinol--cytochrome-c reductase subunit 9"
/protein_id="NP_011699.1"
/db_xref="GI:6321622"
/db_xref="SGD:S000003415"
/db_xref="GeneID:853095"
/translation="MSFSSLYKTFFKRNAVFVGTIFAGAFVFQTVFDTAITSWYENHN
KGKLWKDVKARIAAGDGDDDDE"
gene complement(859901..865753)
/gene="UBR1"
/locus_tag="YGR184C"
/gene_synonym="PTR1"
/db_xref="GeneID:853096"
mRNA complement(859901..865753)
/gene="UBR1"
/locus_tag="YGR184C"
/gene_synonym="PTR1"
/product="E3 ubiquitin-protein ligase UBR1"
/transcript_id="NM_001181313.1"
/db_xref="GI:296145217"
/db_xref="GeneID:853096"
CDS complement(859901..865753)
/gene="UBR1"
/locus_tag="YGR184C"
/gene_synonym="PTR1"
/EC_number="6.3.2.-"
/note="E3 ubiquitin ligase (N-recognin); forms heterodimer
with Rad6p to ubiquitinate substrates in the N-end rule
pathway; regulates peptide transport via Cup9p
ubiquitination; plays a major role in targeting cytosolic
misfolded proteins for degradation; mutation in human UBR1
causes Johansson-Blizzard Syndrome (JBS)"
/codon_start=1
/product="E3 ubiquitin-protein ligase UBR1"
/protein_id="NP_011700.1"
/db_xref="GI:6321623"
/db_xref="SGD:S000003416"
/db_xref="GeneID: 