GenomeNet

Database: RefSeq
Entry: NC_001140
LinkDB: NC_001140
Original site: NC_001140 
LOCUS       NC_001140             562643 bp    DNA     linear   CON 15-JUN-2015
DEFINITION  Saccharomyces cerevisiae S288c chromosome VIII, complete sequence.
ACCESSION   NC_001140
VERSION     NC_001140.6  GI:330443590
DBLINK      BioProject: PRJNA128
            Assembly: GCF_000146045.2
KEYWORDS    RefSeq.
SOURCE      Saccharomyces cerevisiae S288c
  ORGANISM  Saccharomyces cerevisiae S288c
            Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina;
            Saccharomycetes; Saccharomycetales; Saccharomycetaceae;
            Saccharomyces.
REFERENCE   1  (bases 1 to 562643)
  AUTHORS   Goffeau,A., Barrell,B.G., Bussey,H., Davis,R.W., Dujon,B.,
            Feldmann,H., Galibert,F., Hoheisel,J.D., Jacq,C., Johnston,M.,
            Louis,E.J., Mewes,H.W., Murakami,Y., Philippsen,P., Tettelin,H. and
            Oliver,S.G.
  TITLE     Life with 6000 genes
  JOURNAL   Science 274 (5287), 546 (1996)
   PUBMED   8849441
REFERENCE   2  (bases 1 to 562643)
  AUTHORS   Johnston,M., Andrews,S., Brinkman,R., Cooper,J., Ding,H., Dover,J.,
            Du,Z., Favello,A., Fulton,L., Gattung,S. et al.
  TITLE     Complete nucleotide sequence of Saccharomyces cerevisiae chromosome
            VIII
  JOURNAL   Science 265 (5181), 2077-2082 (1994)
   PUBMED   8091229
REFERENCE   3  (bases 1 to 562643)
  CONSRTM   NCBI Genome Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2015) National Center for Biotechnology
            Information, NIH, Bethesda, MD 20894, USA
REFERENCE   4  (bases 1 to 562643)
  CONSRTM   Saccharomyces Genome Database
  TITLE     Direct Submission
  JOURNAL   Submitted (04-MAY-2012) Department of Genetics, Stanford
            University, Stanford, CA 94305-5120, USA
  REMARK    Protein update by submitter
REFERENCE   5  (bases 1 to 562643)
  CONSRTM   Saccharomyces Genome Database
  TITLE     Direct Submission
  JOURNAL   Submitted (31-MAR-2011) Department of Genetics, Stanford
            University, Stanford, CA 94305-5120, USA
  REMARK    Sequence update by submitter
REFERENCE   6  (bases 1 to 562643)
  CONSRTM   Saccharomyces Genome Database
  TITLE     Direct Submission
  JOURNAL   Submitted (11-DEC-2009) Department of Genetics, Stanford
            University, Stanford, CA 94305-5120, USA
COMMENT     REVIEWED REFSEQ: This record has been curated by SGD. The reference
            sequence is identical to BK006934.
            On Apr 26, 2011 this sequence version replaced gi:82795252.
            Sequence assembly version R64-2-1.
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..562643
                     /organism="Saccharomyces cerevisiae S288c"
                     /mol_type="genomic DNA"
                     /strain="S288c"
                     /db_xref="taxon:559292"
                     /chromosome="VIII"
     telomere        complement(1..5505)
                     /note="TEL08L; Telomeric region on the left arm of
                     Chromosome VIII; composed of an X element core sequence,
                     an X element combinatorial repeat, a short Y' element, and
                     a short terminal stretch of telomeric repeats"
                     /db_xref="SGD:S000028891"
     gene            complement(<445..>3311)
                     /locus_tag="YHL050C"
                     /db_xref="GeneID:856335"
     mRNA            complement(join(<445..1897,2671..>3311))
                     /locus_tag="YHL050C"
                     /product="hypothetical protein"
                     /transcript_id="NM_001179130.1"
                     /db_xref="GI:296145321"
                     /db_xref="GeneID:856335"
     CDS             complement(join(445..1897,2671..3311))
                     /locus_tag="YHL050C"
                     /note="hypothetical protein; potential Cdc28p substrate"
                     /codon_start=1
                     /product="hypothetical protein"
                     /protein_id="NP_011813.1"
                     /db_xref="GI:6321737"
                     /db_xref="SGD:S000001042"
                     /db_xref="GeneID:856335"
                     /translation="MADTPSVAVQAPPGYGKTELFHLPLIALASKGDVEYVSFLFVPY
                     TVLLANCMIRLGRCGCLNVAPVRNFIEEGCDGVTDLYVGIYDDLASTNFTDRIAAWEN
                     IVECTFRTNNVKLGYLIVDELHNFETEVYRQSQFGGITNLDFDAFEKAIFLSGTAPEA
                     VADAALQRIGLTGLAKKSMDINELKRSEDLSRGLSSYPTRMFNLIKEKSKVPLGTNAT
                     TTASTNVRTSATTTASINVRTSATTTASINVRTSATTTESTNSNTNATTTESTNSSTN
                     ATTTASTNSSTNATTTESTNASAKEDANKDGNAEDNRFHPVTDINKEPYKRKGSQMVL
                     LERKKLKAQFPNTSENMNVLQFLGFRSDEIKHLFLYGIDIYFCPEGVFTQYGLCKGCQ
                     KMFELCVCWAGQKVSYRRMAWEALAVERMLRNDEEYKEYLEDIEPYHGDPVGYLKFFS
                     VKRREIYSQIQRNYAWYLAITRRRETISVLDSTRGKQGSQVFRMSGRQIKELYYKVWS
                     NLRESKTEVLQYFLNWDEKKCQEEWEAKDDTVFVEALEKVGVFQRLRSMTSAGLQGPQ
                     YVKLQFSRHHRQLRSRYELSLGMHLRDQLALGVTPSKVPHWTAFLSMLIGLFYNKTFR
                     QKLEYLLEQISEVWLLPHWLDLANVEVLAADNTRVPLYMLMVAVHKELDSDDVPDGRF
                     DIILLCRDSSREVGE"
     gene            complement(<3726..>4541)
                     /locus_tag="YHL049C"
                     /db_xref="GeneID:856336"
     mRNA            complement(<3726..>4541)
                     /locus_tag="YHL049C"
                     /product="hypothetical protein"
                     /transcript_id="NM_001179129.1"
                     /db_xref="GI:296145322"
                     /db_xref="GeneID:856336"
     CDS             complement(3726..4541)
                     /locus_tag="YHL049C"
                     /codon_start=1
                     /product="hypothetical protein"
                     /protein_id="NP_011814.1"
                     /db_xref="GI:6321738"
                     /db_xref="SGD:S000001041"
                     /db_xref="GeneID:856336"
                     /translation="MKVSDRRKFEKANFDEFESALNNKNDLVHCPSITLFESIPTEVR
                     SFYEDEKSGLIKVVKFRTGAMDRKRSFEKIVVSVMVGKNVQKFLTFVEDEPDFQGGPI
                     PSKYLIPKKINLMVYTLFQVHTLKFNRKDYDTLSLFYLNRGYYNELSFRVLERCHEIA
                     SARPNDSSTMRTFTDFVSGAPIVRSLQKSTIRKYGYNLAPHMFLLLHVDELSIFSAYQ
                     ASLPGEKKVDTERLKRDLCPRKPTEIKYFSQICNDMMNKKDRLGDVLHVCCPS"
     rep_origin      5471..6401
                     /note="ARS801;
                     Putative replication origin; identified in multiple array
                     studies, not yet confirmed by plasmid-based assay"
                     /db_xref="SGD:S000130145"
     gene            complement(<5663..>5797)
                     /locus_tag="YHL048C-A"
                     /db_xref="GeneID:1466524"
     mRNA            complement(<5663..>5797)
                     /locus_tag="YHL048C-A"
                     /product="hypothetical protein"
                     /transcript_id="NM_001184650.1"
                     /db_xref="GI:296145323"
                     /db_xref="GeneID:1466524"
     CDS             complement(5663..5797)
                     /locus_tag="YHL048C-A"
                     /note="hypothetical protein; identified by expression
                     profiling and mass spectrometry"
                     /codon_start=1
                     /product="hypothetical protein"
                     /protein_id="NP_878084.1"
                     /db_xref="GI:33438802"
                     /db_xref="SGD:S000028829"
                     /db_xref="GeneID:1466524"
                     /translation="MHDIWVITTSPACFEILYKYCKQKGRARMGGLIVKIIRFNHASV
                     "
     gene            <6401..>7546
                     /gene="COS8"
                     /locus_tag="YHL048W"
                     /db_xref="GeneID:856337"
     mRNA            <6401..>7546
                     /gene="COS8"
                     /locus_tag="YHL048W"
                     /product="Cos8p"
                     /transcript_id="NM_001179128.1"
                     /db_xref="GI:296145324"
                     /db_xref="GeneID:856337"
     CDS             6401..7546
                     /gene="COS8"
                     /locus_tag="YHL048W"
                     /note="Nuclear membrane protein; member of the DUP380
                     subfamily of conserved, often subtelomerically-encoded
                     proteins; regulation suggests a potential role in the
                     unfolded protein response"
                     /codon_start=1
                     /product="Cos8p"
                     /protein_id="NP_011815.1"
                     /db_xref="GI:6321739"
                     /db_xref="SGD:S000001040"
                     /db_xref="GeneID:856337"
                     /translation="MKENEVKDEKSVDVLSFKQLEFQKTVLPQDVFRNELTWFCYEIY
                     KSLAFRIWMLLWLPLSVWWKLSSNWIHPLIVSLLVLFLGPFFVLVICGLSRKRSLSKQ
                     LIQFCKEITEDTPSSDPHDWEVVAANLNSYFYENKTWNTKYFFFNAMSCQKAFKTTLL
                     EPFSLKKDESAKVKSFKDSVPYIEEALQVYAAGFDKEWKLFNTEKEESPFDLEDIQLP
                     KEAYRFKLTWILKRIFNLRCLPLFLYYFLIVYTSGNADLISRFLFPVVMFFIMTRDFQ
                     NMRMIVLSVKMEHKMQFLSTIINEQESGANGWDEIAKKMNRYLFEKKVWNNEEFFYDG
                     LDCEWFFRRFFYRLLSLKKPMWFASLNVELWPYIKEAQSARNEKPLK"
     rep_origin      7702..7767
                     /note="ARS802;
                     Autonomously Replicating Sequence"
                     /db_xref="SGD:S000118356"
     LTR             complement(7994..8225)
                     /note="Ty5 LTR"
                     /db_xref="SGD:S000006986"
     gene            complement(<8351..>10213)
                     /gene="ARN2"
                     /locus_tag="YHL047C"
                     /gene_synonym="TAF1"
                     /db_xref="GeneID:856338"
     mRNA            complement(<8351..>10213)
                     /gene="ARN2"
                     /locus_tag="YHL047C"
                     /gene_synonym="TAF1"
                     /product="Arn2p"
                     /transcript_id="NM_001179127.2"
                     /db_xref="GI:330443579"
                     /db_xref="GeneID:856338"
     CDS             complement(8351..10213)
                     /gene="ARN2"
                     /locus_tag="YHL047C"
                     /gene_synonym="TAF1"
                     /note="Transporter; member of the ARN family of
                     transporters that specifically recognize siderophore-iron
                     chelates; responsible for uptake of iron bound to the
                     siderophore triacetylfusarinine C"
                     /codon_start=1
                     /product="Arn2p"
                     /protein_id="NP_011816.2"
                     /db_xref="GI:330443580"
                     /db_xref="SGD:S000001039"
                     /db_xref="GeneID:856338"
                     /translation="MIEVPEDNRSSQTKRKNTEKNCNELMVDEKMDDDSSPRDEMKDK
                     LKGTKSLIIRKSELMAKKYDTWQLKAIFLFSAFICTFAYGLDSSIRGTYMTYAMNSYS
                     AHSLISTVSVIVLMISAVSQVIFGGLSDIFGRLTLFLVSIVLYIVGTIIQSQAYDVQR
                     YAAGAVFYYVGLVGVMLQVVLMLSDNSSLKWRLFYTLIPSWPSIITTWVSGSVVEAAN
                     PLENWSWNIAMWAFIFPLCCIPLILCMLHMRWKVRNDVEWKELQDEKSYYQTHGLVQM
                     LVQLFWKLDVVGVLLFTAGVGCILVPLTLAGGVSTNWRNSKIIGPFVLGFVLVPGFIY
                     WESRLALVPFAPFKLLKDRGVWAPLGIMFFICFVYQMAAGYLYTILVVAVDESASSAT
                     RIINLYSFVTAVVAPFLGLIVTRSSRLKSYIIFGGSLYFITMGLFYRYRSGQDADGGI
                     IAGMVIWGLSSCLFDYPTIVSIQSVTSHENMATVTALNYTVFRIGGAVAAAISGAIWT
                     QSLYPKLLHYMGDADLATAAYGSPLTFILSNPWGTPVRSAMVEAYRHVQKYEVIVALV
                     FSAPMFLLTFCVRDPRLTEDFAQKLPDREYVQTKEDDPINDWIAKRFAKALGRS"
     gene            complement(<11923..>12285)
                     /gene="PAU13"
                     /locus_tag="YHL046C"
                     /db_xref="GeneID:856339"
     mRNA            complement(<11923..>12285)
                     /gene="PAU13"
                     /locus_tag="YHL046C"
                     /product="seripauperin PAU13"
                     /transcript_id="NM_001179126.1"
                     /db_xref="GI:296145326"
                     /db_xref="GeneID:856339"
     CDS             complement(11923..12285)
                     /gene="PAU13"
                     /locus_tag="YHL046C"
                     /note="hypothetical protein; member of the seripauperin
                     multigene family encoded mainly in subtelomeric regions;
                     expression is induced after ethanol shock"
                     /codon_start=1
                     /product="seripauperin PAU13"
                     /protein_id="NP_011817.1"
                     /db_xref="GI:6321741"
                     /db_xref="SGD:S000001038"
                     /db_xref="GeneID:856339"
                     /translation="MVKLTSIAAGVAAIAATASATTTLAQSDERVNLVELGVYVSDIR
                     AHLAQYYMFQAAHPTETYPVEVAEAVFNYGDFTTMLTGIAPDQVTRMITGVPWYSSRL
                     KPAISSALSKDGIYTITN"
     gene            <13565..>14272
                     /locus_tag="YHL044W"
                     /db_xref="GeneID:856341"
     mRNA            <13565..>14272
                     /locus_tag="YHL044W"
                     /product="DUP240 family protein"
                     /transcript_id="NM_001179124.1"
                     /db_xref="GI:296145327"
                     /db_xref="GeneID:856341"
     CDS             13565..14272
                     /locus_tag="YHL044W"
                     /note="Putative integral membrane protein; member of
                     DUP240 gene family; green fluorescent protein (GFP)-fusion
                     protein localizes to the plasma membrane in a punctate
                     pattern"
                     /codon_start=1
                     /product="DUP240 family protein"
                     /protein_id="NP_011819.1"
                     /db_xref="GI:6321743"
                     /db_xref="SGD:S000001036"
                     /db_xref="GeneID:856341"
                     /translation="MSSELLISNSKPRPEGLRKLCEGETVILPRDITPSKCAYFLKQN
                     IVFISYIFIHIIITIILNRLALSAHGNTLIIILAALLITISLFLLLLLPYLSCSRYKL
                     RCLDDDCKFKLLAEVITHKPNMDLSTWDRIAYDMNQFVYDRRICADRSFFYDGSYCYQ
                     VFKKLVATPYLVNSNMNSIYADLEMRSNGATNINDSGNSSLHIELGTYIFKALAVFRN
                     SVDKYWEDKYPEMGVTV"
     gene            <14901..>15413
                     /gene="ECM34"
                     /locus_tag="YHL043W"
                     /db_xref="GeneID:856342"
     mRNA            <14901..>15413
                     /gene="ECM34"
                     /locus_tag="YHL043W"
                     /product="Ecm34p"
                     /transcript_id="NM_001179123.1"
                     /db_xref="GI:296145328"
                     /db_xref="GeneID:856342"
     CDS             14901..15413
                     /gene="ECM34"
                     /locus_tag="YHL043W"
                     /note="hypothetical protein; member of the DUP380
                     subfamily of conserved, often subtelomerically-encoded
                     proteins"
                     /codon_start=1
                     /product="Ecm34p"
                     /protein_id="NP_011820.1"
                     /db_xref="GI:6321744"
                     /db_xref="SGD:S000001035"
                     /db_xref="GeneID:856342"
                     /translation="MEGRKSEDEKNEAALACDVFESSNAKLPKNVFRSSFTWYCYEVI
                     NRSAFHIWLLLCLTLIVGWKVFSGIGGRRPSDSNMDGPQTKHKRNPGFLRRHSTIVIL
                     VISLAVSFSWEAFKMYRERTFGKQITQFAKEIIKSAPSTDMESWDRVAADFNSYMYEN
                     KLWNTEYFFC"
     gene            <15667..>16119
                     /locus_tag="YHL042W"
                     /db_xref="GeneID:856343"
     mRNA            <15667..>16119
                     /locus_tag="YHL042W"
                     /product="hypothetical protein"
                     /transcript_id="NM_001179122.1"
                     /db_xref="GI:296145329"
                     /db_xref="GeneID:856343"
     CDS             15667..16119
                     /locus_tag="YHL042W"
                     /note="hypothetical protein; member of the DUP380
                     subfamily of conserved, often subtelomerically-encoded
                     proteins"
                     /codon_start=1
                     /product="hypothetical protein"
                     /protein_id="NP_011821.1"
                     /db_xref="GI:6321745"
                     /db_xref="SGD:S000001034"
                     /db_xref="GeneID:856343"
                     /translation="MKQRFSQVATVIFFVMSIRSPRNLGFFFTLALFVVLVCSQEWFS
                     FEMNRSCSMKVEHRMQFLSTIISEHQKSDVNCWDQIAKKMNVYLFEQKVSGSDVFFLD
                     GADCERFFERNFLRYLPSRKSSHPDLPIAELLPYIRKADIACAGKQLI"
     gene            complement(<19088..>20971)
                     /gene="ARN1"
                     /locus_tag="YHL040C"
                     /db_xref="GeneID:856345"
     mRNA            complement(<19088..>20971)
                     /gene="ARN1"
                     /locus_tag="YHL040C"
                     /product="Arn1p"
                     /transcript_id="NM_001179120.1"
                     /db_xref="GI:296145330"
                     /db_xref="GeneID:856345"
     CDS             complement(19088..20971)
                     /gene="ARN1"
                     /locus_tag="YHL040C"
                     /note="ARN family transporter for siderophore-iron
                     chelates; responsible for uptake of iron bound to
                     ferrirubin, ferrirhodin, and related siderophores; protein
                     increases in abundance and relocalizes to the vacuole upon
                     DNA replication stress"
                     /codon_start=1
                     /product="Arn1p"
                     /protein_id="NP_011823.1"
                     /db_xref="GI:6321747"
                     /db_xref="SGD:S000001032"
                     /db_xref="GeneID:856345"
                     /translation="MESVHSRDPVKEEKKHVFMGMEHELNPETHNDSNSDSYGLPQLS
                     EKYNALRQNRSLIIQQTEIIGSAYNKWYLQAILLLSAFICGYGYGLDGNIRYIYTGYA
                     TSSYSEHSLLSTINVINAVVSAASQIIYARLSDVFGRLYLFISAVILYVVGTIIQSQA
                     YDVQRYAAGAIFYNAGYVGVILILLIILSDFSSLKWRLLYQFVPTWPFIINTWIAGNI
                     TSRANPVVNWSWDVGMWAFIFPLSCVPIVLCMLHMQWRARKTPEWHALKGQKSYYQEH
                     GFIKILKQLFWMLDVVGVLLMGCSLGCILVPLTLAGGVKTTWNDSRLIGPFVLGFVLI
                     PILWIWEYRFARDPILPYRLVKDRAVWSSMGISFLIDFIYYMAADYLYTVMIVAVNES
                     VKSATRIATLSSFVSTVASPFFALLVTRCTRLKPFIMFGCALWMVAMGLLYHFRGGSQ
                     SHSGIIGALCVWGVGTTLFTYPVTVSVQSAVSHENMATVTALNYTLYRIGSAVGSAVS
                     GAIWTQTLYKQILKRMGDVALATTAYESPYTFIETYTWGTPQRNALMNAYKYVQRLET
                     IVALVFCVPLIAFSLCLRDPKLTDTVAVEYIEDGEYVDTKDNDPILDWFEKLPSKFTF
                     KRE"
     gene            <21783..>23540
                     /gene="EFM1"
                     /locus_tag="YHL039W"
                     /db_xref="GeneID:856346"
     mRNA            <21783..>23540
                     /gene="EFM1"
                     /locus_tag="YHL039W"
                     /product="Efm1p"
                     /transcript_id="NM_001179119.1"
                     /db_xref="GI:296145331"
                     /db_xref="GeneID:856346"
     CDS             21783..23540
                     /gene="EFM1"
                     /locus_tag="YHL039W"
                     /EC_number="2.1.1.-"
                     /note="Lysine methyltransferase; involved in the
                     monomethylation of eEF1A (Tef1p/Tef2p); SET-domain family
                     member; predicted involvement in ribosome biogenesis;
                     green fluorescent protein (GFP)-fusion protein localizes
                     to the cytoplasm"
                     /codon_start=1
                     /product="Efm1p"
                     /protein_id="NP_011824.1"
                     /db_xref="GI:6321748"
                     /db_xref="SGD:S000001031"
                     /db_xref="GeneID:856346"
                     /translation="MITQTELDNCLQWAQNNGAFIDPKISFRITEDAGVSAFVNEKFS
                     PKPDQALIRVPETLLITSQQALSEFSQAANERSLLNSVTQLYLSKLKFGTDAVHLKSF
                     YKPYLDVLPLHLPQPYFWSTDEVMNLHGTDVYLTMRDTLNKLVKEWRMLFQALSIEHS
                     SQDKQFLSLFQENKDSAVVPLEQFCAHINGCKLEDSEWNSFVAYLWSYCIFNSRAFPR
                     VILGRAGTDRTNLNEGFLYPIVDLLNHKNDVPVRWEMNEQNELCFMSQTTTFSAQDEL
                     FNNYGNISNEKCLLNYGFWDSSNKFDFSRLTLKLPSTLVSGLPVDFNKSGNFVTDDGE
                     TTILQFSLKISEPLPPVLLALFAYLSKLKSEETPTVRSVLEGIDQLTSVVSQRLLFYK
                     NFKIKTSSTQKLRPHVIKLIKLYYQDNKKILNATTEKLSVLQKKIYSNNKEFSLSFKT
                     IFKNDKIFANSLLLVFGAINYEDLITKDCLNDALLLWIVKLINDKSNNQGGFIKQTFK
                     EVSDSIVIEKEDVMEFLPFYKKYFPNLSERIPEIYSVGDWGIRQFIVADTAIDRLVWI
                     RKSNKEPIFLMKKAYDLQI"
     gene            complement(<23617..>25509)
                     /gene="CBP2"
                     /locus_tag="YHL038C"
                     /db_xref="GeneID:856347"
     mRNA            complement(<23617..>25509)
                     /gene="CBP2"
                     /locus_tag="YHL038C"
                     /product="Cbp2p"
                     /transcript_id="NM_001179118.1"
                     /db_xref="GI:296145332"
                     /db_xref="GeneID:856347"
     CDS             complement(23617..25509)
                     /gene="CBP2"
                     /locus_tag="YHL038C"
                     /note="Required for splicing of the group I intron bI5 of
                     the COB pre-mRNA; nuclear-encoded mitochondrial protein
                     that binds to the RNA to promote splicing; also involved
                     in but not essential for splicing of the COB bI2 intron
                     and the intron in the 21S rRNA gene"
                     /codon_start=1
                     /product="Cbp2p"
                     /protein_id="NP_011825.1"
                     /db_xref="GI:6321749"
                     /db_xref="SGD:S000001030"
                     /db_xref="GeneID:856347"
                     /translation="MVNWQTLFMVSLRRQGSSSRYRYKFNMENITHQVFPRCKQAFKK
                     TNLSYEYCDLEGVLYNISLTDLQKLLLRDINAPREHAFKIVRTDLTQKSSKKRIQHWE
                     RIAPMFDHPLSLYEKLFSEMDEDFKPSFEWQQLIRVRCKDDKLKLQRVIWPKSIFSNF
                     CRGIGVKKSTYDRLLEQNNGEVPMFVNPANAKPLPLFQVSDEAMIGEFDGIGIFPYFV
                     DKHREFFVTEVDKLKTKIASPLCTLNERKRIEKANAGRILANEEGKPFYLDANSATTR
                     IAGGNVVTLKQLLERSVSHKTLWSKQSNKDRTCPGDILRATILSNDFSIRQLRAEFCK
                     NFILYNIFTILQRNKKSIRSFSGNDNAPSFQFSWNVWDSYIWKQYQETESMKIPTDQA
                     SLINYKTKYDSFLHDLQTYSALVISEMKWNQFSIFQNDETTLSRFEHITLILQTVLTK
                     SKMIRIFQPNLYKFMQDDLRPTLMELVGFTESINATIEPGFANEQSLQSANGLKKLAN
                     QLLYFEQEIYGEKFRVNRPIQLRPITLSANYKIVILDKKNAIPEIFQTLLKFMTQITT
                     YFVKDLSEVELHGHMHCIDKKMLDKSKFMYLYEEKSNEEVKAASPQKEKIVDNIIGLL
                     SNDEEH"
     gene            <26241..>27881
                     /gene="MUP3"
                     /locus_tag="YHL036W"
                     /db_xref="GeneID:856349"
     mRNA            <26241..>27881
                     /gene="MUP3"
                     /locus_tag="YHL036W"
                     /product="Mup3p"
                     /transcript_id="NM_001179116.1"
                     /db_xref="GI:296145333"
                     /db_xref="GeneID:856349"
     CDS             26241..27881
                     /gene="MUP3"
                     /locus_tag="YHL036W"
                     /note="Low affinity methionine permease; similar to Mup1p"
                     /codon_start=1
                     /product="Mup3p"
                     /protein_id="NP_011827.1"
                     /db_xref="GI:6321751"
                     /db_xref="SGD:S000001028"
                     /db_xref="GeneID:856349"
                     /translation="MEPLLFNSGKANPSQDVFIDVEVGDITTKYGSTNTGSFSSMDTV
                     EAQAIKAETARFMEVPQGRHLGVFSTVVLFVSRIMGSGIFAVPSVILLNTGGNKLIYF
                     AIWVFSAAIAFAGLYLFLEFGSWIPKSGGRKNFLERSFERPRLLISVVFSCYSVLTGY
                     ALTGSIVFGKYVLSAFGVTDDSWSKYVSISFIIFAVLIHGVSVRHGVFIQNALGGLKL
                     IMIVLMCFAGLYTLFFYKSTGQVAWDLPVTQVEKDSLLSVSSIATAFISSFFCFSGWD
                     TVHTVTSEIKNPVKTLKVSGPLSLIICFVCYTMMNVAYLKVLTYEEIVSAGPLVGSVL
                     FTKLFGPRVGGKFIAFSIAISAASNILVVIYSISRVNQEIFKEGYLPFSIHMSKNWPF
                     DAPLPSISLCGFITIAWILILPKEGESFNYLVSMDGYGNQFFLLLVAIGLFIWRFKHK
                     NEVPEIRASTFGVLAIITLSLYMLMAPFFADPSLNRVGFLPPYQIMSLLVIVACFFFW
                     LVKFVLLPKFFHYKLLPKITYLHDGLIVTEWVKKPCLC"
     gene            complement(<27978..>32756)
                     /gene="VMR1"
                     /locus_tag="YHL035C"
                     /db_xref="GeneID:856350"
     mRNA            complement(<27978..>32756)
                     /gene="VMR1"
                     /locus_tag="YHL035C"
                     /product="putative ATP-binding cassette multidrug
                     transporter VMR1"
                     /transcript_id="NM_001179115.1"
                     /db_xref="GI:296145334"
                     /db_xref="GeneID:856350"
     CDS             complement(27978..32756)
                     /gene="VMR1"
                     /locus_tag="YHL035C"
                     /note="Vacuolar membrane protein; involved in multiple
                     drug resistance and metal sensitivity; ATP-binding
                     cassette (ABC) family member involved in drug transport;
                     potential Cdc28p substrate; induced under respiratory
                     conditions; VMR1 has a paralog, YBT1, that arose from the
                     whole genome duplication"
                     /codon_start=1
                     /product="putative ATP-binding cassette multidrug
                     transporter VMR1"
                     /protein_id="NP_011828.1"
                     /db_xref="GI:6321752"
                     /db_xref="SGD:S000001027"
                     /db_xref="GeneID:856350"
                     /translation="MGTDPLIIRNNGSFWEVDDFTRLGRTQLLSYYLPLAIIASIGIF
                     ALCRSGLSRYVRSAECDLVNEYLFGAQEERKEDNSIERLLRNSNTQANYVNVKKQGRI
                     LKLRHFDITTIDVKQIDAKNHGGLTFSRPSTSDHLRKSSEIVLMSLQIIGLSFLRVTK
                     INIELTNRDVTTLLLFWLILLSLSILRVYKRSTNLWAICFTAHTTIWISTWIPIRSVY
                     IGNIDDVPSQIFYIFEFVITSTLQPIKLTSPIKDNSSIIYVRDDHTSPSREHISSILS
                     CITWSWITNFIWEAQKNTIKLKDIWGLSMEDYSIFILKGFTRRNKHINNLTLALFESF
                     KTYLLIGMLWVLVNSIVNLLPTILMKRFLEIVDNPNRSSSCMNLAWLYIIGMFICRLT
                     LAICNSQGQFVSDKICLRIRAILIGEIYAKGLRRRLFTSPKTSSDSDSISANLGTIIN
                     LISIDSFKVSELANYLYVTVQAVIMIIVVVGLLFNFLGVSAFAGISIILVMFPLNFLL
                     ANLLGKFQKQTLKCTDQRISKLNECLQNIRIVKYFAWERNIINEIKSIRQKELRSLLK
                     KSLVWSVTSFLWFVTPTLVTGVTFAICTFVQHEDLNAPLAFTTLSLFTLLKTPLDQLS
                     NMLSFINQSKVSLKRISDFLRMDDTEKYNQLTISPDKNKIEFKNATLTWNENDSDMNA
                     FKLCGLNIKFQIGKLNLILGSTGSGKSALLLGLLGELNLISGSIIVPSLEPKHDLIPD
                     CEGLTNSFAYCSQSAWLLNDTVKNNIIFDNFYNEDRYNKVIDACGLKRDLEILPAGDL
                     TEIGEKGITLSGGQKQRISLARAVYSSAKHVLLDDCLSAVDSHTAVWIYENCITGPLM
                     KNRTCILVTHNVSLTLRNAHFAIVLENGKVKNQGTITELQSKGLFKEKYVQLSSRDSI
                     NEKNANRLKAPRKNDSQKIEPVTENINFDANFVNDGQLIEEEEKSNGAISPDVYKWYL
                     KFFGGFKALTALFALYITAQILFISQSWWIRHWVNDTNVRINAPGFAMDTLPLKGMTD
                     SSKNKHNAFYYLTVYFLIGIIQAMLGGFKTMMTFLSGMRASRKIFNNLLDLVLHAQIR
                     FFDVTPVGRIMNRFSKDIEGVDQELIPYLEVTIFCLIQCASIIFLITVITPRFLTVAV
                     IVFVLYFFVGKWYLTASRELKRLDSITKSPIFQHFSETLVGVCTIRAFGDERRFILEN
                     MNKIDQNNRAFFYLSVTVKWFSFRVDMIGAFIVLASGSFILLNIANIDSGLAGISLTY
                     AILFTDGALWLVRLYSTFEMNMNSVERLKEYSSIEQENYLGHDEGRILLLNEPSWPKD
                     GEIEIENLSLRYAPNLPPVIRNVSFKVDPQSKIGIVGRTGAGKSTIITALFRLLEPIT
                     GCIKIDGQDISKIDLVTLRRSITIIPQDPILFAGTIKSNVDPYDEYDEKKIFKALSQV
                     NLISSHEFEEVLNSEERFNSTHNKFLNLHTEIAEGGLNLSQGERQLLFIARSLLREPK
                     IILLDEATSSIDYDSDHLIQGIIRSEFNKSTILTIAHRLRSVIDYDRIIVMDAGEVKE
                     YDRPSELLKDERGIFYSMCRDSGGLELLKQIAKQSSKMMK"
     gene            complement(<33193..>34077)
                     /gene="SBP1"
                     /locus_tag="YHL034C"
                     /gene_synonym="SSB1; SSBR1"
                     /db_xref="GeneID:856351"
     mRNA            complement(<33193..>34077)
                     /gene="SBP1"
                     /locus_tag="YHL034C"
                     /gene_synonym="SSB1; SSBR1"
                     /product="Sbp1p"
                     /transcript_id="NM_001179114.1"
                     /db_xref="GI:296145335"
                     /db_xref="GeneID:856351"
     CDS             complement(33193..34077)
                     /gene="SBP1"
                     /locus_tag="YHL034C"
                     /gene_synonym="SSB1; SSBR1"
                     /note="Protein that binds eIF4G and has a role in
                     repression of translation; has an RGG motif; found in
                     cytoplasmic P bodies; binds to mRNAs under glucose
                     starvation stress, most often in the 5' UTR; found
                     associated with small nucleolar RNAs snR10 and snR11; SBP1
                     has a paralog, RNP1, that arose from the whole genome
                     duplication"
                     /codon_start=1
                     /product="Sbp1p"
                     /protein_id="NP_011829.1"
                     /db_xref="GI:6321753"
                     /db_xref="SGD:S000001026"
                     /db_xref="GeneID:856351"
                     /translation="MSAEIEEATNAVNNLSINDSEQQPRAPTHKTVIDPEDTIFIGNV
                     AHECTEDDLKQLFVEEFGDEVSVEIPIKEHTDGHIPASKHALVKFPTKIDFDNIKENY
                     DTKVVKDREIHIKRARTPGQMQRGGFRGRGGFRGRGGFRGGFRGGYRGGFRGRGNFRG
                     RGGARGGFNGQKREKIPLDQMERSKDTLYINNVPFKATKEEVAEFFGTDADSISLPMR
                     KMRDQHTGRIFTSDSANRGMAFVTFSGENVDIEAKAEEFKGKVFGDRELTVDVAVIRP
                     ENDEEEIEQETGSEEKQE"
     gene            complement(<35255..>36025)
                     /gene="RPL8A"
                     /locus_tag="YHL033C"
                     /gene_synonym="MAK7"
                     /db_xref="GeneID:856352"
     mRNA            complement(<35255..>36025)
                     /gene="RPL8A"
                     /locus_tag="YHL033C"
                     /gene_synonym="MAK7"
                     /product="ribosomal 60S subunit protein L8A"
                     /transcript_id="NM_001179113.1"
                     /db_xref="GI:296145336"
                     /db_xref="GeneID:856352"
     CDS             complement(35255..36025)
                     /gene="RPL8A"
                     /locus_tag="YHL033C"
                     /gene_synonym="MAK7"
                     /note="Ribosomal 60S subunit protein L8A; required for
                     processing of 27SA3 pre-rRNA to 27SB pre-rRNA during
                     assembly of large ribosomal subunit; depletion leads to a
                     turnover of pre-rRNA; L8 binds to Domain I of 25S and 5.8
                     S rRNAs; mutation results in decreased amounts of free 60S
                     subunits; homologous to mammalian ribosomal protein L7A,
                     no bacterial homolog; RPL8A has a paralog, RPL8B, that
                     arose from the whole genome duplication"
                     /codon_start=1
                     /product="ribosomal 60S subunit protein L8A"
                     /protein_id="NP_011830.1"
                     /db_xref="GI:6321754"
                     /db_xref="SGD:S000001025"
                     /db_xref="GeneID:856352"
                     /translation="MAPGKKVAPAPFGAKSTKSNKTRNPLTHSTPKNFGIGQAVQPKR
                     NLSRYVKWPEYVRVQRQKKILSIRLKVPPTIAQFQYTLDRNTAAETFKLFNKYRPETA
                     AEKKERLTKEAAAVAEGKSKQDASPKPYAVKYGLNHVVALIENKKAKLVLIANDVDPI
                     ELVVFLPALCKKMGVPYAIVKGKARLGTLVNQKTSAVAALTEVRAEDEAALAKLVSTI
                     DANFADKYDEVKKHWGGGILGNKAQAKMDKRAKNSDSA"
     gene            complement(<36379..>38508)
                     /gene="GUT1"
                     /locus_tag="YHL032C"
                     /db_xref="GeneID:856353"
     mRNA            complement(<36379..>38508)
                     /gene="GUT1"
                     /locus_tag="YHL032C"
                     /product="glycerol kinase"
                     /transcript_id="NM_001179112.1"
                     /db_xref="GI:296145337"
                     /db_xref="GeneID:856353"
     CDS             complement(36379..38508)
                     /gene="GUT1"
                     /locus_tag="YHL032C"
                     /EC_number="2.7.1.30"
                     /note="Glycerol kinase; converts glycerol to
                     glycerol-3-phosphate; glucose repression of expression is
                     mediated by Adr1p and Ino2p-Ino4p; derepression of
                     expression on non-fermentable carbon sources is mediated
                     by Opi1p and Rsf1p"
                     /codon_start=1
                     /product="glycerol kinase"
                     /protein_id="NP_011831.1"
                     /db_xref="GI:6321755"
                     /db_xref="SGD:S000001024"
                     /db_xref="GeneID:856353"
                     /translation="MFPSLFRLVVFSKRYIFRSSQRLYTSLKQEQSRMSKIMEDLRSD
                     YVPLIASIDVGTTSSRCILFNRWGQDVSKHQIEYSTSASKGKIGVSGLRRPSTAPARE
                     TPNAGDIKTSGKPIFSAEGYAIQETKFLKIEELDLDFHNEPTLKFPKPGWVECHPQKL
                     LVNVVQCLASSLLSLQTINSERVANGLPPYKVICMGIANMRETTILWSRRTGKPIVNY
                     GIVWNDTRTIKIVRDKWQNTSVDRQLQLRQKTGLPLLSTYFSCSKLRWFLDNEPLCTK
                     AYEENDLMFGTVDTWLIYQLTKQKAFVSDVTNASRTGFMNLSTLKYDNELLEFWGIDK
                     NLIHMPEIVSSSQYYGDFGIPDWIMEKLHDSPKTVLRDLVKRNLPIQGCLGDQSASMV
                     GQLAYKPGAAKCTYGTGCFLLYNTGTKKLISQHGALTTLAFWFPHLQEYGGQKPELSK
                     PHFALEGSVAVAGAVVQWLRDNLRLIDKSEDVGPIASTVPDSGGVVFVPAFSGLFAPY
                     WDPDARATIMGMSQFTTASHIARAAVEGVCFQARAILKAMSSDAFGEGSKDRDFLEEI
                     SDVTYEKSPLSVLAVDGGMSRSNEVMQIQADILGPCVKVRRSPTAECTALGAAIAANM
                     AFKDVNERPLWKDLHDVKKWVFYNGMEKNEQISPEAHPNLKIFRSESDDAERRKHWKY
                     WEVAVERSKGWLKDIEGEHEQVLENFQ"
     gene            complement(<38815..>39486)
                     /gene="GOS1"
                     /locus_tag="YHL031C"
                     /db_xref="GeneID:856354"
     mRNA            complement(<38815..>39486)
                     /gene="GOS1"
                     /locus_tag="YHL031C"
                     /product="Gos1p"
                     /transcript_id="NM_001179111.1"
                     /db_xref="GI:296145338"
                     /db_xref="GeneID:856354"
     CDS             complement(38815..39486)
                     /gene="GOS1"
                     /locus_tag="YHL031C"
                     /note="v-SNARE protein involved in Golgi transport;
                     homolog of the mammalian protein GOS-28/GS28"
                     /codon_start=1
                     /product="Gos1p"
                     /protein_id="NP_011832.1"
                     /db_xref="GI:6321756"
                     /db_xref="SGD:S000001023"
                     /db_xref="GeneID:856354"
                     /translation="MSSQPSFVTIRGKAISLETQTESLLSKYSTFAQTTSSEQTGQEK
                     KIDKQLEGILGQRQDVIDSLTQICDSNPAISASKLSQLHRHKEILQDHWKSFRNIRSS
                     IQQERNRLNLLFSVKNDIANSTTDAPAPIGDADEYIQNETRRIDQSNNVVDRLISQAW
                     ETRSQFHSQSNVLNTANNKVLQTLQRIPGVNQLIMKINTRRKKNAFVLATITTLCILF
                     LFFTW"
     gene            <40084..>45690
                     /gene="ECM29"
                     /locus_tag="YHL030W"
                     /db_xref="GeneID:856355"
     mRNA            <40084..>45690
                     /gene="ECM29"
                     /locus_tag="YHL030W"
                     /product="Ecm29p"
                     /transcript_id="NM_001179110.1"
                     /db_xref="GI:296145339"
                     /db_xref="GeneID:856355"
     CDS             40084..45690
                     /gene="ECM29"
                     /locus_tag="YHL030W"
                     /note="Scaffold protein; assists in association of the
                     proteasome core particle with the regulatory particle;
                     inhibits proteasomal ATPase activity; degraded by the
                     mature proteasome after assembly; contains HEAT-like
                     repeats; protein increases in abundance and relocalizes
                     from nucleus to cytoplasm upon DNA replication stress"
                     /codon_start=1
                     /product="Ecm29p"
                     /protein_id="NP_011833.1"
                     /db_xref="GI:6321757"
                     /db_xref="SGD:S000001022"
                     /db_xref="GeneID:856355"
                     /translation="MSISSDEAKEKQLVEKAELRLAIADSPQKFETNLQTFLPPLLLK
                     LASPHASVRTAVFSALKNLISRINTLPQVQLPVRALIVQAKEPNLAAQQDSTNVRLYS
                     LLLASKGIDRLSLQDRQQLLPLVVSNISCLTGTVAARMFHILLKLILEWVAPQESSHE
                     QEEFVQFLQLDNDGFSFLMRQFTRFFLLVPSKQVQVSQQPLSRGYTCPGLSLTDVAFF
                     TYDAGVTFNKEQLNKFKKAIFQFVCRGMAATQTIEQSPRMIELMEFLCVVSTDSTNLS
                     DDAAQFMKRFPMPYENEEFITFLQTLYIGNTANGRPPVKAILQEKILSILNRSHFATT
                     KAECISLICSIGLHSSEYKLRSLTLSFIRHVAKLNYKNLNPASSSPSSTDFSTCIVSL
                     IRNNLHAEGWPKLQLGPQTPAFNTAILQRQLQYETLGDILKRDFELVSDLSYIEFLFE
                     SLKNDLPQFRSSIQESLLSLVGHLSILPQQSKLKLKNLLRKNLSIDEQQREDNNDAVN
                     SIMALKFVSIKFTNAAFPFHDPEARLFNIWGTVRTNRFDIIEESFKGLQPFWFRVNNA
                     SINTSATVKTSDLLGSHLSETEFPPFREFLQVLIDQLDSEAASITRKSLNNAVRFSKQ
                     CLISNAIYGKKTMVIQDEDWSVRIDKALELDDTVVSRVNEMVQGMNDDIFIRYLTLLS
                     NEFTATNSKGEQIAIFPYQDPIFGSVLLTLLNFVSNNVLRRLEILVPDLYHLVIMKFQ
                     SLSDNDLAVCATIIGIISTAIADSTHVKRITKIAQSQTMAETYVASYVVPRLYLKDQT
                     NHIESDSILNLLNILTTHLSHPGTNKDMILKLVCQVTKFGLLLQVSAQERKDFLKKVM
                     DTIQDKLINDVTAIQTWSYLSLYSTDLENSSLFQEKLLETNVSKQNDFLFSVGESLSV
                     VAGKWSSKYLIKQIDIPNFNVEIMQQKFPATNVTTILDEIFSGCDSTKPSLRKASCIW
                     LLSYIQYLGHLPEVSSKCNDIHLRFMRFLADRDEFIQDSAARGLSLVYEIGGSDLKES
                     MVKGLLKSFTESTAGSASTSATGISGSVSEETELFEPGVLNTGDGSISTYKDILNLAS
                     EVGDPALVYKFMSLAKSSALWSSRKGIAFGLGAIMSKSSLEELLLKDQQTAKKLIPKL
                     YRYRFDPFQAVSRSMTDIWNTLIPESSLTISLYFNDILDELLCGMANKEWRVREASTS
                     ALLQLIQSQPQEKFSEKMLKIWTMAFRTMDDIKDSVREVGTKFTTVLAKILARSIDVE
                     KGVNPTKSKEILDNILPFLWGPHGLNSDAEEVRNFALTTLIDLVKHSPGAIKPFTPKL
                     IYDFITLFSSIEPQVINYLALNAANYNIDANVIDTQRKNGVTNSPLFQTIEKLINNSD
                     DCMMEEIINVVIKASRKSVGLPSKVASSLVIIILVKRYSIEMKPYSGKLLKVCLTMFE
                     DRNESVNIAFAISMGYLFKVSALDKCIKYSEKLITKYFEPTSTENNKKVVGTAIDSIL
                     NYAKSEFDNVASVFMPLIFIACNDEDKDLETLYNKIWTEASSSGAGTVKLYLPEILNV
                     LCVNIKSNDFSIRKTCAKSVIQLCGGINDSIPYPQIVKLFDISREALSGRSWDGKEHI
                     VAALVSLTEKFSQTVADNNDLQESINHVMYTEVSRKSMKYVKKILPLYARYINVNPQE
                     ETITFLIEKAKEMIRLLGSESDDSEGSIKQTSDESTIKRIKPNTEITQKSSKENIENE
                     EYVINLLKVSVDICNNSKSRYPMNLLEFIIDEIAYLFHNDRIIHTWRTQLAASEIGIS
                     IVGRFSTISSADFIQNVGRLWDQTFPINCNKETIENVKLQMIKFGGLIIQKIPSLQNN
                     IEENLRLLNSIDSTSRIELELKNIGL"
     gene            complement(<45929..>47968)
                     /gene="OCA5"
                     /locus_tag="YHL029C"
                     /db_xref="GeneID:856356"
     mRNA            complement(<45929..>47968)
                     /gene="OCA5"
                     /locus_tag="YHL029C"
                     /product="Oca5p"
                     /transcript_id="NM_001179109.1"
                     /db_xref="GI:296145340"
                     /db_xref="GeneID:856356"
     CDS             complement(45929..47968)
                     /gene="OCA5"
                     /locus_tag="YHL029C"
                     /note="Cytoplasmic protein required for replication of
                     Brome mosaic virus; S. cerevisiae is a model system for
                     studying replication of positive-strand RNA viruses in
                     their natural hosts"
                     /codon_start=1
                     /product="Oca5p"
                     /protein_id="NP_011834.1"
                     /db_xref="GI:6321758"
                     /db_xref="SGD:S000001021"
                     /db_xref="GeneID:856356"
                     /translation="MHDKKSPMANSHYLKNLKQQFRNKNLIETTIHLVKCNDHDSLAF
                     LARTYGVPPQLRHVVWPILLKYHPMCISPNITSNTISWDPITNDFILNDPFLKSKAPT
                     DKQDKSDDENILPYDIESIILHDLKKYFHSRSNPAGSSSNANTTNIATPTPVSSSDAS
                     TISSMEVLSPSLDYEFQIIETLKNAIVKFLLKWSKIFKYESGLAWIALGLAEWYPIYP
                     YETMSPFNETHSFYEVEDYVVLSGRKHALLSTNNGNNGNSNSSSNNTNNNNTNITSGM
                     HNLSINTNTSLHNSPYISHTLSYLYKEYPLPFELRSKLPTKPIFSFSALFERLALVIL
                     HCPDTILAHKQLKNDSNASSSSKANSNFNTNYFPIISGGDLSFQTQVFFKVFSSILPE
                     LYQPLTEESSLQPSSSRNSWIYWWLKCSGAKALQRQDRGRVWDLLLGWRPKPNMDTIN
                     FFLNYNDKKMDHLYHDTPQCDNEQYWMKDWIALYNNDPFWFPDLDSMALGSKKFPYDY
                     SVFKELILRNRYGGTQSKAQKDNTVPSPGSDSNDKSELKLPFSSIDPHMQLIFIFIAI
                     LQFNEFKLLEFEEAEISEFLNNVPLLTKFDDSSYRKLYENTESSITSLPSSPTTSTMA
                     SLQSSSNSSAHISNYHMLIEVGNDAKASHCFDDLLNMAGDIWRKWLWRELEESSL"
     gene            <48763..>50580
                     /gene="WSC4"
                     /locus_tag="YHL028W"
                     /gene_synonym="YFW1; YHC8"
                     /db_xref="GeneID:856357"
     mRNA            <48763..>50580
                     /gene="WSC4"
                     /locus_tag="YHL028W"
                     /gene_synonym="YFW1; YHC8"
                     /product="Wsc4p"
                     /transcript_id="NM_001179108.1"
                     /db_xref="GI:296145341"
                     /db_xref="GeneID:856357"
     CDS             48763..50580
                     /gene="WSC4"
                     /locus_tag="YHL028W"
                     /gene_synonym="YFW1; YHC8"
                     /note="Endoplasmic reticulum (ER) membrane protein;
                     involved in the translocation of soluble secretory
                     proteins and insertion of membrane proteins into the ER
                     membrane; may also have a role in the stress response but
                     has only partial functional overlap with WSC1-3"
                     /codon_start=1
                     /product="Wsc4p"
                     /protein_id="NP_011835.1"
                     /db_xref="GI:6321759"
                     /db_xref="SGD:S000001020"
                     /db_xref="GeneID:856357"
                     /translation="MQTSMVSAKVSIWLVCSVICSSLVRATQSVCSSQNTATTDGVRN
                     QFQSNGWCSNNCAGHQFAIVQGFMCWCSDSEPSTQTSVGDCSGTCPGYGYEDCGNADK
                     DLFGYIYLGQTPLSSVQSVETSTESSVYVSSSSITSSSSTSIVDTTTISPTLTSTSTT
                     PLTTASTSTTPSTDITSALPTTTSTKLSTSIPTSTTSSTSTTTSTSSSTSTTVSVTSS
                     TSTTTSTTSSTLISTSTSSSSSSTPTTTSSAPISTSTTSSTSTSTSTTSPTSSSAPTS
                     SSNTTPTSTTFTTTSPSTAPSSTTVTYTSTTASPITSTITSVNLQTSLKYSVITVTSV
                     HTMDTNISEITSRYLTMKKVITQIYSSTLGATPTSAVATTSASVGGRITNNNNSNTTN
                     SNTPTNKSTEKKGYWDSPGKIAATFVVVGVVCLVIICILIYLIHHYRTRPARKAQDFE
                     NEYQSKFYQSKYPNEVTTTTLHTPSPSSNSTFSTPRLIYTDEKGQIMSESPSPRQSTY
                     SLTAGSPPNDPSTLASPFHDPILPRRTSTFLHSPIQKQHEKMESNVTLGEDTVLVDQR
                     LDPSKMLNTLANDDATNHSTISLSDNVDYSRRVLRLMNE"
     gene            <51111..>52988
                     /gene="RIM101"
                     /locus_tag="YHL027W"
                     /gene_synonym="RIM1"
                     /db_xref="GeneID:856358"
     mRNA            <51111..>52988
                     /gene="RIM101"
                     /locus_tag="YHL027W"
                     /gene_synonym="RIM1"
                     /product="alkaline-responsive transcriptional regulator
                     RIM101"
                     /transcript_id="NM_001179107.1"
                     /db_xref="GI:296145342"
                     /db_xref="GeneID:856358"
     CDS             51111..52988
                     /gene="RIM101"
                     /locus_tag="YHL027W"
                     /gene_synonym="RIM1"
                     /note="Cys2His2 zinc-finger transcriptional repressor;
                     involved in alkaline responsive gene repression as part of
                     adaptation to alkaline conditions; involved in cell wall
                     assembly; required for alkaline pH-stimulated haploid
                     invasive growth and sporulation; activated by
                     alkaline-dependent proteolytic processing which results in
                     removal of the C-terminal tail; similar to A. nidulans
                     PacC"
                     /codon_start=1
                     /product="alkaline-responsive transcriptional regulator
                     RIM101"
                     /protein_id="NP_011836.1"
                     /db_xref="GI:6321760"
                     /db_xref="SGD:S000001019"
                     /db_xref="GeneID:856358"
                     /translation="MVPLEDLLNKENGTAAPQHSRESIVENGTDVSNVTKKDGLPSPN
                     LSKRSSDCSKRPRIRCTTEAIGLNGQEDERMSPGSTSSSCLPYHSTSHLNTPPYDLLG
                     ASAVSPTTSSSSDSSSSSPLAQAHNPAGDDDDADNDGDSEDITLYCKWDNCGMIFNQP
                     ELLYNHLCHDHVGRKSHKNLQLNCHWGDCTTKTEKRDHITSHLRVHVPLKPFGCSTCS
                     KKFKRPQDLKKHLKIHLESGGILKRKRGPKWGSKRTSKKNKSCASDAVSSCSASVPSA
                     IAGSFKSHSTSPQILPPLPVGISQHLPSQQQQRAISLNQLCSDELSQYKPVYSPQLSA
                     RLQTILPPLYYNNGSTVSQGANSRSMNVYEDGCSNKTIANATQFFTKLSRNMTNNYIL
                     QQSGGSTESSSSSGRIPVAQTSYVQPPNAPSYQSVQGGSSISATANTATYVPVRLAKY
                     PTGPSLTEHLPPLHSNTAGGVFNRQSQYAMPHYPSVRAAPSYSSSGCSILPPLQSKIP
                     MLPSRRTMAGGTSLKPNWEFSLNQKSCTNDIIMSKLAIEEVDDESEIEDDFVEMLGIV
                     NIIKDYLLCCVMEDLDDEESEDKDEENAFLQESLEKLSLQNQMGTNSVRILTKYPKIL
                     V"
     gene            complement(<53219..>54166)
                     /locus_tag="YHL026C"
                     /db_xref="GeneID:856359"
     mRNA            complement(<53219..>54166)
                     /locus_tag="YHL026C"
                     /product="hypothetical protein"
                     /transcript_id="NM_001179106.1"
                     /db_xref="GI:296145343"
                     /db_xref="GeneID:856359"
     CDS             complement(53219..54166)
                     /locus_tag="YHL026C"
                     /note="hypothetical protein; transcriptionally regulated
                     by Upc2p via an upstream sterol response element; YHL026C
                     is not an essential gene; in 2005 the start site was moved
                     141 nt upstream (see Locus History)"
                     /codon_start=1
                     /product="hypothetical protein"
                     /protein_id="NP_011837.2"
                     /db_xref="GI:82795253"
                     /db_xref="SGD:S000001018"
                     /db_xref="GeneID:856359"
                     /translation="MKSSEPAPATPTGFRNSIWFIIFYLFVIQALGSAIISGGIEFAI
                     AYAMYHSRVDLITLWAFPHTISGDCALSLFIQVGLTWASEEILVGFDDYKRPVFRLNK
                     WITKPSPLKTESNEEIPPPKKRFIVDYFESKDNVVAKQNTLYHKHNWLFGYLEVNRGI
                     IPKGKEATLKGFLTSQFIHDSTQSKFMNFIEWFVQKFIRSMILAIAMFIVIWPVTMGI
                     LAGIGHKVGSHDYYFNDYPLPQVMKLIYAVVIAFVCTPVAIIVIVLRNQFHEELYYEG
                     LANGTLQQDQEVCSTGNRSSGSTDQDISTTKQQSQEAVA"
     gene            <54851..>55849
                     /gene="SNF6"
                     /locus_tag="YHL025W"
                     /db_xref="GeneID:856360"
     mRNA            <54851..>55849
                     /gene="SNF6"
                     /locus_tag="YHL025W"
                     /product="Snf6p"
                     /transcript_id="NM_001179105.1"
                     /db_xref="GI:296145344"
                     /db_xref="GeneID:856360"
     CDS             54851..55849
                     /gene="SNF6"
                     /locus_tag="YHL025W"
                     /note="Subunit of the SWI/SNF chromatin remodeling
                     complex; involved in transcriptional regulation; functions
                     interdependently in transcriptional activation with Snf2p
                     and Snf5p; relocates to the cytosol under hypoxic
                     conditions"
                     /codon_start=1
                     /product="Snf6p"
                     /protein_id="NP_011838.1"
                     /db_xref="GI:6321762"
                     /db_xref="SGD:S000001017"
                     /db_xref="GeneID:856360"
                     /translation="MGVIKKKRSHHGKASRQQYYSGVQVGGVGSMGAINNNIPSLTSF
                     AEENNYQYGYSGSSAGMNGRSLTYAQQQLNKQRQDFERVRLRPEQLSNIIHDESDTIS
                     FRSNLLKNFISSNDAFNMLSLTTVPCDRIEKSRLFSEKTIRYLMQKQHEMKTQAAELQ
                     EKPLTPLKYTKLIAAAEDGSRSTKDMIDAVFEQDSHLRYQPDGVVVHRDDPALVGKLR
                     GDLREAPADYWTHAYRDVLAQYHEAKERIRQKEVTAGEAQDEASLQQQQQQDLQQQQQ
                     VVTTVASQSPHATATEKEPVPAVVDDPLENMFGDYSNEPFNTNFDDEFGDLDAVFF"
     gene            <56649..>58790
                     /gene="RIM4"
                     /locus_tag="YHL024W"
                     /db_xref="GeneID:856361"
     mRNA            <56649..>58790
                     /gene="RIM4"
                     /locus_tag="YHL024W"
                     /product="Rim4p"
                     /transcript_id="NM_001179104.1"
                     /db_xref="GI:296145345"
                     /db_xref="GeneID:856361"
     CDS             56649..58790
                     /gene="RIM4"
                     /locus_tag="YHL024W"
                     /note="Putative RNA-binding protein; required for the
                     expression of early and middle sporulation genes"
                     /codon_start=1
                     /product="Rim4p"
                     /protein_id="NP_011839.1"
                     /db_xref="GI:6321763"
                     /db_xref="SGD:S000001016"
                     /db_xref="GeneID:856361"
                     /translation="MKTEISTADSLRDPPSNGLKADSELVIREDIDQFLPSEVSSLGS
                     DHQNDGEDSDTDSDNFLQDPEDDVDEESTGRGTVTTTSTSTESRGRPSSCIFVASLAA
                     ALSDDELCLSVTENFKKYGDLARVKVLRDNANRPYAFVQYNNDHDAKHALIRAQGTLL
                     NGRRLRCEPAKVNRTLYLKNQQSIDFNEISQICEKFGGLEQIVPDRTDNQYTRRYTYP
                     ISSANSWFVQFVYRDDAIRAYANLRTDPNWIIEWAQNINVPKNYNLLHKSKFKSSKYH
                     QNNGIINNDGSNNNDNNNSNNNNREDSRRNGDVIEEECGHVHGSDSEEKLTSDGIYDD
                     EDKDSEITIDKRSIFVGQLDKETTREELNRRFSTHGKIQDINLIFKPTNIFAFIKYET
                     EEAAAAALESENHAIFLNKTMHVQYKEVGGRHNRKFSGKNGGSNFNHHQFFSTRSGKT
                     FTGPELNLAPPPINMYRKMSGGSQQESETMMPYMPMGPMPMGPPPPNAASLSDFDMFP
                     PSYSTFMKGMMPLRRKSMPNSWSSPSSKSVNSENESVNGGDENSELPSEIPESSGRYN
                     AANSFTTYNNSSAGNSNNNNNNNNSNSNKSQYKKRYARRSSYGYNEVPPKPYYFQPYY
                     YHPMQYHMGPMGPLHPSQGSAGNHHPYMMVYPMSPPPPSGLDGSMIPPPINVSQSHAA
                     NHGSTHVHANEFISNDTGDINEDNKAYSLDY"
     gene            complement(<59123..>62563)
                     /gene="NPR3"
                     /locus_tag="YHL023C"
                     /gene_synonym="RMD11"
                     /db_xref="GeneID:856362"
     mRNA            complement(<59123..>62563)
                     /gene="NPR3"
                     /locus_tag="YHL023C"
                     /gene_synonym="RMD11"
                     /product="Npr3p"
                     /transcript_id="NM_001179103.1"
                     /db_xref="GI:296145346"
                     /db_xref="GeneID:856362"
     CDS             complement(59123..62563)
                     /gene="NPR3"
                     /locus_tag="YHL023C"
                     /gene_synonym="RMD11"
                     /note="Subunit of SEA (Seh1-associated), Npr2/3, and Iml1p
                     complexes; Npr2/3 complex mediates downregulation of TORC1
                     activity upon amino acid limitation; SEA complex is a
                     coatomer-related complex that associates dynamically with
                     the vacuole; Iml1p complex (Iml1p-Npr2p-Npr3p) is required
                     for non-nitrogen-starvation (NNS)-induced autophagy;
                     required for Npr2p phosphorylation and Iml1p-Npr2p
                     interaction; null mutant shows delayed meiotic DNA
                     replication and double-strand break repair"
                     /codon_start=1
                     /product="Npr3p"
                     /protein_id="NP_011840.1"
                     /db_xref="GI:6321764"
                     /db_xref="SGD:S000001015"
                     /db_xref="GeneID:856362"
                     /translation="MDECLPNSCLLGVHLVISTHSGPQIVYHYPPSNTAFLTNNPTKH
                     QHLYGNHANLNKNTSTNKEEKLFNSGSTKTASQIALNESAKSYNTAITPSMTNTNTNN
                     VTLPPTRSHANTVGSQSSIPAATNGVGYRKTDIEDTSRTFQYQETESETSSSGLSDSE
                     LSTDYLDISSDSFSISSSLSSSSLSSSPSSSSSSSPPQDGLSRTNSSFQSTDSMSPTS
                     PQMIMENDSISVAESYLDSGTNNKSRAASKRSQNFFHKLSTKKSTDSKTHSPVRKLKS
                     KPSQSTKKGNKLLKNTSNETDGNAFTGSCSISSKKSLSSTGEHNQELRNSSLNDTPGQ
                     SPHHYHHRYHHYHKNAATSQRNSHTQYDVEEEDMEVSAMLQDGKISMNEIFFEEENFQ
                     DINKILEFDNDFVAEFCSPEREMCNTRFEFTVDNFCFLGLPIHVDSQGRWRKSKHKNK
                     TRSKRSSSTTTNISRKKSIASKISSLSENTLKKVNSGEADTVYDSNIGHEASTDTPNL
                     RINTDVSGNEFEREKEDLGKNMNMFHVCFVMNPHLIEYNKRIDDMYQFVVTRLSLLLR
                     YVQSKTSYISSECHIILKEKERVLKHSKTYQSIRGAGNKGKYLYQRILAKSSLARALT
                     ECVDKIQRNEIACLEINDDKVISLQIPIQNEFEKMPNFKLQPVLRGSYLTSILNMKFL
                     EKSSLRIESQNRQNDQAQFSDTNNNIYRFGNNINSTGHCGAANVDDGDDNESNYYCDD
                     NDDLLNYALLLLDEPNNIISSLETFSYQDDIGTIILKHLVRNIQPNIPLRSYRYLITD
                     LLDNPSSLDDLTTETNSLESSILRSCALHLMYWRHARIVIPLSSKYTYIVSPLAPIQG
                     YTIDDYKSTSQNDGNVKKMDDRENNKSGSDRVPLIYQNSMLFRSKFPSLPSLPIFLSL
                     LSTDKPQAYSNIIPSREHKPVYLNALAWLIQYGYVTQLLTFINIRVDKHIKMAVDEDL
                     EKEGFRKTNTARRPSMDYKKTDKKLDDEDGQSRDANASEACSGKNEGMQSNDNNKDVD
                     EKDNENDSRVDDRDDNEIAIADEEEILHFEYDDPEMQHDYTIILEPERATAIEKRWLY
                     RCIYGQPSDIQILFNKLLKYFNGKVPMELVIIKEEISRHDLKKLLNALDKYLIEIHHW
                     "
     gene            62755..62826
                     /locus_tag="tH(GUG)H"
                     /db_xref="GeneID:856363"
     tRNA            62755..62826
                     /locus_tag="tH(GUG)H"
                     /product="tRNA-His"
                     /note="Histidine tRNA (tRNA-His), predicted by tRNAscan-SE
                     analysis"
                     /db_xref="SGD:S000006597"
                     /db_xref="GeneID:856363"
     gene            complement(<62961..>64157)
                     /gene="SPO11"
                     /locus_tag="YHL022C"
                     /db_xref="GeneID:856364"
     mRNA            complement(<62961..>64157)
                     /gene="SPO11"
                     /locus_tag="YHL022C"
                     /product="Spo11p"
                     /transcript_id="NM_001179102.1"
                     /db_xref="GI:296145347"
                     /db_xref="GeneID:856364"
     CDS             complement(62961..64157)
                     /gene="SPO11"
                     /locus_tag="YHL022C"
                     /note="Meiosis-specific protein that initiates meiotic
                     recombination; initiates meiotic recombination by
                     catalyzing the formation of double-strand breaks in DNA
                     via a transesterification reaction; required for
                     homologous chromosome pairing and synaptonemal complex
                     formation"
                     /codon_start=1
                     /product="Spo11p"
                     /protein_id="NP_011841.1"
                     /db_xref="GI:6321765"
                     /db_xref="SGD:S000001014"
                     /db_xref="GeneID:856364"
                     /translation="MALEGLRKKYKTRQELVKALTPKRRSIHLNSNGHSNGTPCSNAD
                     VLAHIKHFLSLAANSLEQHQQPISIVFQNKKKKGDTSSPDIHTTLDFPLNGPHLCTHQ
                     FKLKRCAILLNLLKVVMEKLPLGKNTTVRDIFYSNVELFQRQANVVQWLDVIRFNFKL
                     SPRKSLNIIPAQKGLVYSPFPIDIYDNILTCENEPKMQKQTIFPGKPCLIPFFQDDAV
                     IKLGTTSMCNIVIVEKEAVFTKLVNNYHKLSTNTMLITGKGFPDFLTRLFLKKLEQYC
                     SKLISDCSIFTDADPYGISIALNYTHSNERNAYICTMANYKGIRITQVLAQNNEVHNK
                     SIQLLSLNQRDYSLAKNLIASLTANSWDIATSPLKNVIIECQREIFFQKKAEMNEIDA
                     RIFEYK"
     rep_origin      64296..64371
                     /note="ARS805;
                     Autonomously Replicating Sequence"
                     /db_xref="SGD:S000114849"
     gene            complement(<64462..>65859)
                     /gene="AIM17"
                     /locus_tag="YHL021C"
                     /gene_synonym="FMP12"
                     /db_xref="GeneID:856365"
     mRNA            complement(<64462..>65859)
                     /gene="AIM17"
                     /locus_tag="YHL021C"
                     /gene_synonym="FMP12"
                     /product="Aim17p"
                     /transcript_id="NM_001179101.1"
                     /db_xref="GI:296145348"
                     /db_xref="GeneID:856365"
     CDS             complement(64462..65859)
                     /gene="AIM17"
                     /locus_tag="YHL021C"
                     /gene_synonym="FMP12"
                     /EC_number="1.14.11.-"
                     /note="hypothetical protein; the authentic, non-tagged
                     protein is detected in highly purified mitochondria in
                     high-throughput studies; null mutant displays reduced
                     frequency of mitochondrial genome loss"
                     /codon_start=1
                     /product="Aim17p"
                     /protein_id="NP_011842.1"
                     /db_xref="GI:6321766"
                     /db_xref="SGD:S000001013"
                     /db_xref="GeneID:856365"
                     /translation="MLRSNLCRGSRILARLTTTPRTYTSAATAAAANRGHIIKTYFNR
                     DSTTITFSMEESSKPVSVCFNNVFLRDASHSAKLVTTGELYHNEKLTAPQDIQISEDG
                     KSLVVKWKDGGHHQFPLQFFIDYKGSSFVSPATRKQESRYRPQLWNKRILKDNVKDLL
                     SVSYNEFIDPKDDSKLFQTLVNLQKFGIAFISGTPSSSSEGLTIQKICERIGPIRSTV
                     HGEGTFDVNASQATSVNAHYANKDLPLHTDLPFLENVPGFQILQSLPATEGEDPNTRP
                     MNYFVDAFYATRNVRESDFEAYEALQIVPVNYIYENGDKRYYQSKPLIEHHDINEDNT
                     LLGNYEALIKCINYSPPYQAPFTFGIYDKPSDLNNNLDLNLITTPAKLTERFLFKSFI
                     RGLNLFESHINDFNNQFRLQLPENCCVIFNNRRILHANSLTSSNQQWLKGCYFDSDTF
                     KSKLKFLEEKFPHDK"
     gene            complement(<66242..>67456)
                     /gene="OPI1"
                     /locus_tag="YHL020C"
                     /db_xref="GeneID:856366"
     mRNA            complement(<66242..>67456)
                     /gene="OPI1"
                     /locus_tag="YHL020C"
                     /product="transcriptional regulator OPI1"
                     /transcript_id="NM_001179100.1"
                     /db_xref="GI:296145349"
                     /db_xref="GeneID:856366"
     CDS             complement(66242..67456)
                     /gene="OPI1"
                     /locus_tag="YHL020C"
                     /note="Transcriptional regulator of a variety of genes;
                     phosphorylation by protein kinase A stimulates Opi1p
                     function in negative regulation of phospholipid
                     biosynthetic genes; involved in telomere maintenance; null
                     exhibits disrupted mitochondrial metabolism and low
                     cardiolipin content, strongly correlated with
                     overproduction of inositol"
                     /codon_start=1
                     /product="transcriptional regulator OPI1"
                     /protein_id="NP_011843.1"
                     /db_xref="GI:6321767"
                     /db_xref="SGD:S000001012"
                     /db_xref="GeneID:856366"
                     /translation="MSENQRLGLSEEEVEAAEVLGVLKQSCRQKSQPSEDVSQADKMP
                     ASESSTTPLNILDRVSNKIISNVVTFYDEINTNKRPLKSIGRLLDDDDDEHDDYDYND
                     DEFFTNKRQKLSRAIAKGKDNLKEYKLNMSIESKKRLVTCLHLLKLANKQLSDKISCL
                     QDLVEKEQVHPLHKQDGNARTTTGAGEDETSSDEDDDDEEFFDASEQVNASEQSIVVK
                     MEVVGTVKKVYSLISKFTANSLPEPARSQVRESLLNLPTNWFDSVHSTSLPHHASFHY
                     ANCEEQKVEQQQQQQQQQQQQQLLQQQLLQQQQQKRNKDGDDSASPSSSVTANGKVLI
                     LAKESLEMVRNVMGVVDSTLGKAEEWVKQKQEVKEMIRERFLQQQQQYRQQQQKDGNY
                     VKPSQDNVDSKD"
     gene            complement(<67731..>69548)
                     /gene="APM2"
                     /locus_tag="YHL019C"
                     /db_xref="GeneID:856367"
     mRNA            complement(<67731..>69548)
                     /gene="APM2"
                     /locus_tag="YHL019C"
                     /product="Apm2p"
                     /transcript_id="NM_001179099.1"
                     /db_xref="GI:296145350"
                     /db_xref="GeneID:856367"
     CDS             complement(67731..69548)
                     /gene="APM2"
                     /locus_tag="YHL019C"
                     /note="hypothetical protein; homologous to the medium
                     chain of mammalian clathrin-associated protein complex;
                     involved in vesicular transport"
                     /codon_start=1
                     /product="Apm2p"
                     /protein_id="NP_011844.1"
                     /db_xref="GI:6321768"
                     /db_xref="SGD:S000001011"
                     /db_xref="GeneID:856367"
                     /translation="MSSSLFILDENLEPLVSKNIRALPNLSSVLSSFKQCYHDGSPPI
                     LSQNDWFFIHLKRDFLHFVSVIHTTDKPNIDLMTILAFLEQFYHLLQKYFEIEVLTKN
                     VILDNILLVLELIDECIDFGIVQVTDPSIIKDYIRVKVNVPRVTVDNEEWSPGEESSS
                     SSGSDSDSEYSNTNKRKDKKKKRKKKKGTKGKSVGKSKLKSIMVNNKENRGINVVETV
                     KETLRNKNDTGKEAANDELPNDGNDLYINGDIAKTIIMPISWRTKGIHYAKNEFFLDV
                     IERVQYLMDFEKGVIRKNLIHGEIVCRCYLSGMPKLKISINKILNRDPQFMSNSSFHQ
                     CVSLDSINTIEKDEEKNSDDDAGLQAATDAREIEFIPPDGEFVLCQYELKRHVKDAPM
                     VRLKDFEIKPKLKKFKIQIVTKIQTNFKPTNSTSKLNVRIPLTKVFQEYKIDLSKQIR
                     FKANIGKVVFNLSDDFLLWEIQTMKGHREHSTNKSSQYNSDEDDPNTCASMVAEFPLF
                     NQEEYDRLQEEMKTSMNPPPLRTGPRLEELYRQVHDQQTSHVTPRDKLVNIDFEIPYC
                     TCSGLKVEYLKVEEPQLQYQSFPWVRYKTVSDEEYAYIV"
     gene            <69708..>70070
                     /locus_tag="YHL018W"
                     /db_xref="GeneID:856368"
     mRNA            <69708..>70070
                     /locus_tag="YHL018W"
                     /product="4a-hydroxytetrahydrobiopterin dehydratase"
                     /transcript_id="NM_001179098.1"
                     /db_xref="GI:296145351"
                     /db_xref="GeneID:856368"
     CDS             69708..70070
                     /locus_tag="YHL018W"
                     /EC_number="4.2.1.96"
                     /note="Putative 4a-hydroxytetrahydrobiopterin dehydratase;
                     green fluorescent protein (GFP)-fusion protein localizes
                     to mitochondria and is induced in response to the
                     DNA-damaging agent MMS"
                     /codon_start=1
                     /product="4a-hydroxytetrahydrobiopterin dehydratase"
                     /protein_id="NP_011845.1"
                     /db_xref="GI:6321769"
                     /db_xref="SGD:S000001010"
                     /db_xref="GeneID:856368"
                     /translation="MHNKIVRIASSALTGGKLLEKLKPLTRWEVQWDPNKTKCLGITR
                     EVTFKDYETTWAFLTRVSMRSHLWGHHPLIHTSYTWVKLELHTHDIDPKDGAHSQLSD
                     IDVRMAKRIDSYIDEMTT"
     gene            <70276..>71874
                     /locus_tag="YHL017W"
                     /db_xref="GeneID:856369"
     mRNA            <70276..>71874
                     /locus_tag="YHL017W"
                     /product="hypothetical protein"
                     /transcript_id="NM_001179097.1"
                     /db_xref="GI:296145352"
                     /db_xref="GeneID:856369"
     CDS             70276..71874
                     /locus_tag="YHL017W"
                     /note="hypothetical protein; green fluorescent protein
                     (GFP)-fusion protein co-localizes with clathrin-coated
                     vesicles; YHL017W has a paralog, PTM1, that arose from the
                     whole genome duplication"
                     /codon_start=1
                     /product="hypothetical protein"
                     /protein_id="NP_011846.1"
                     /db_xref="GI:6321770"
                     /db_xref="SGD:S000001009"
                     /db_xref="GeneID:856369"
                     /translation="MDRTWLLLTWLLLLCGVVQGNQESINQKYHDVCSGMYSKEDFNG
                     KVDPYISFTLEELSLADEDDDGEGVSVAVFDFQDYEHIGVRLPNGEIQYICDDYALDL
                     GLCEDSSEGQFIIQETAIDPFTSKEHKLTSQILTFTQQELGTNDKVYSINKTGYYCVT
                     TSSFISSSSKFKATVNFRNAYGQLDASEAYKMPIYAFLAVAYAVCTLVYSWLCWKHRH
                     ELLPLQRYILVFCIFLTADTIFVWMYYIIENQKGNSSVALHVYMVFISIFSAGKMTFT
                     LLLALLISLGYGIVYPKLDRTLLRRCQIFAIFTFAVCVAFLVQKYSQNSESLSNLILI
                     TAIPLVLCLFAFYYLTLSSMNKTMTYLREQNQVVKLNMYRKLIILCYISLFILFLGLL
                     VSTFAYVGMDTVDMIEQYWKTEFLITDTWPSFVYFLVFVIFAFFWRPTSTSYLLACSH
                     QLPTDMENVSEFDLDDINSLSDEALPNREPRNDYQEHDHNMDIDLASDFEEVPSVNAN
                     TNANNDVLFDVDYDRDAKNDRSTT"
     gene            complement(<72037..>74244)
                     /gene="DUR3"
                     /locus_tag="YHL016C"
                     /db_xref="GeneID:856370"
     mRNA            complement(<72037..>74244)
                     /gene="DUR3"
                     /locus_tag="YHL016C"
                     /product="Dur3p"
                     /transcript_id="NM_001179096.1"
                     /db_xref="GI:296145353"
                     /db_xref="GeneID:856370"
     CDS             complement(72037..74244)
                     /gene="DUR3"
                     /locus_tag="YHL016C"
                     /note="Plasma membrane transporter for both urea and
                     polyamines; expression is highly sensitive to nitrogen
                     catabolite repression and induced by allophanate, the last
                     intermediate of the allantoin degradative pathway"
                     /codon_start=1
                     /product="Dur3p"
                     /protein_id="NP_011847.1"
                     /db_xref="GI:6321771"
                     /db_xref="SGD:S000001008"
                     /db_xref="GeneID:856370"
                     /translation="MGEFKPPLPQGAGYAIVLGLGAVFAGMMVLTTYLLKRYQKEIIT
                     AEEFTTAGRSVKTGLVAAAVVSSWIWCSTLLTSSTKEYADGIFGGYAYAAGACFQIIA
                     FAILAIKTKQMAPNAHTYLELVRTRYGKIGHGCYLFYAIATNILVTSMLLTSGSAVFS
                     DLTGMNTIASCFLLPVGVVVYTLFGGIKATFLTDYMHTCVIIIIVLVFAFKVYATSDV
                     LGSPGKVYDLVREAAKRHPVDGNYQGEYMTMTSKSAGILLIINLIGNFGTVFLDNGYW
                     NKAISASPAASLKAYAIGGLAWFAVPSLISLTMGLACLAVETSPNFPTYPDPLTSFQA
                     NSGLVLPAAAIAIMGKGGAVASLLMIFMAVTSAMSAELIAVSSVFTYDIYREYIDPRA
                     SGKKLIYTSHVACIFFGLAMSGFSVGLYYGGISMGYIYEMMGIIISSAVLPVVLTLCS
                     KDMNLVAAVVSPILGTGLAIMSWLVCTKSLYKELTVDTTFMDYPMLTGNLVALLSPAI
                     FIPILTYVFKPQNFDWEKMKDITRVDETAELVQADPDIQLYDAEANDKEQEEETNSLV
                     SDSEKNDVRVNNEKLIEPNLGVVISNAIFQEDDTQLQNELDEEQRELARGLKIAYFLC
                     VFFALAFLVVWPMPMYGSKYIFSKKFFTGWVVVMIIWLFFSAFAVCIYPLWEGRHGIY
                     TTLRGLYWDLSGQTYKLREWQNSNPQDLHVVTSQISARAHRQSSHFGQVDEII"
     gene            <74699..>74782
                     /locus_tag="YHL015W-A"
                     /db_xref="GeneID:1466525"
     mRNA            <74699..>74782
                     /locus_tag="YHL015W-A"
                     /product="hypothetical protein"
                     /transcript_id="NM_001184649.1"
                     /db_xref="GI:296145354"
                     /db_xref="GeneID:1466525"
     CDS             74699..74782
                     /locus_tag="YHL015W-A"
                     /codon_start=1
                     /product="hypothetical protein"
                     /protein_id="NP_878085.1"
                     /db_xref="GI:33438803"
                     /db_xref="SGD:S000028828"
                     /db_xref="GeneID:1466525"
                     /translation="MTAFASLREPLVLANLKIKVHIYRMKR"
     gene            <75412..>75777
                     /gene="RPS20"
                     /locus_tag="YHL015W"
                     /gene_synonym="URP2"
                     /db_xref="GeneID:856371"
     mRNA            <75412..>75777
                     /gene="RPS20"
                     /locus_tag="YHL015W"
                     /gene_synonym="URP2"
                     /product="ribosomal 40S subunit protein S20"
                     /transcript_id="NM_001179095.1"
                     /db_xref="GI:296145355"
                     /db_xref="GeneID:856371"
     CDS             75412..75777
                     /gene="RPS20"
                     /locus_tag="YHL015W"
                     /gene_synonym="URP2"
                     /note="Protein component of the small (40S) ribosomal
                     subunit; overproduction suppresses mutations affecting RNA
                     polymerase III-dependent transcription; homologous to
                     mammalian ribosomal protein S20 and bacterial S10"
                     /codon_start=1
                     /product="ribosomal 40S subunit protein S20"
                     /protein_id="NP_011848.1"
                     /db_xref="GI:6321772"
                     /db_xref="SGD:S000001007"
                     /db_xref="GeneID:856371"
                     /translation="MSDFQKEKVEEQEQQQQQIIKIRITLTSTKVKQLENVSSNIVKN
                     AEQHNLVKKGPVRLPTKVLKISTRKTPNGEGSKTWETYEMRIHKRYIDLEAPVQIVKR
                     ITQITIEPGVDVEVVVASN"
     gene            complement(<76097..>77314)
                     /gene="YLF2"
                     /locus_tag="YHL014C"
                     /gene_synonym="YLF1"
                     /db_xref="GeneID:856372"
     mRNA            complement(<76097..>77314)
                     /gene="YLF2"
                     /locus_tag="YHL014C"
                     /gene_synonym="YLF1"
                     /product="Ylf2p"
                     /transcript_id="NM_001179094.1"
                     /db_xref="GI:296145356"
                     /db_xref="GeneID:856372"
     CDS             complement(76097..77314)
                     /gene="YLF2"
                     /locus_tag="YHL014C"
                     /gene_synonym="YLF1"
                     /note="hypothetical protein; has weak similarity to E.
                     coli GTP-binding protein gtp1; the authentic, non-tagged
                     protein is detected in highly purified mitochondria in
                     high-throughput studies"
                     /codon_start=1
                     /product="Ylf2p"
                     /protein_id="NP_011849.1"
                     /db_xref="GI:6321773"
                     /db_xref="SGD:S000001006"
                     /db_xref="GeneID:856372"
                     /translation="MNIGGGKFLLGRISNNPTSGIVGLANVGKSTFFQAITNSKLGNP
                     ANYPFATIDAECAKVNIPSVPLSNLLRIYQSAKCVPGTLTIYDIAGLTRGASQGHGLG
                     NKFLNDIRHVEGIFQVVRGFLKEDITHIEGNVDPVRDLSVVQDELILKDLEFLENIRE
                     RLSKKMRMVSKNSKEHQEMKIETELLDALEEHLFNGKKIRHFKDHWNLDEVKILNKHN
                     FLTSKPTLILLNVSPQDYVRNENKFVRNIIEWINEFSPGDKFLLFSAEFESQLMECKG
                     IASEYFDKIKEDTNVSDQQLVSAIPQIILEMRKLLNLISFFTCGPQEVHQWNIREGTT
                     AQEAAGVIHSDLRETFISADVIKYDDLKKMEPPLNESLLKSKGLIKRAGKQYIMQDND
                     IALFKAAGGKIKK"
     gene            complement(<77430..>78353)
                     /gene="OTU2"
                     /locus_tag="YHL013C"
                     /db_xref="GeneID:856373"
     mRNA            complement(<77430..>78353)
                     /gene="OTU2"
                     /locus_tag="YHL013C"
                     /product="Otu2p"
                     /transcript_id="NM_001179093.1"
                     /db_xref="GI:296145357"
                     /db_xref="GeneID:856373"
     CDS             complement(77430..78353)
                     /gene="OTU2"
                     /locus_tag="YHL013C"
                     /note="hypothetical protein; may interact with ribosomes,
                     based on co-purification experiments; member of the
                     ovarian tumor-like (OTU) superfamily of predicted cysteine
                     proteases; shows cytoplasmic localization; protein
                     abundance increases in response to DNA replication stress"
                     /codon_start=1
                     /product="Otu2p"
                     /protein_id="NP_011850.1"
                     /db_xref="GI:6321774"
                     /db_xref="SGD:S000001005"
                     /db_xref="GeneID:856373"
                     /translation="MTGMESGENLENMEDILARHRKENKDLQNKITGMKKQATKSKRK
                     EVNSKCLDLQDKLKTKQENEIRDWKIANNEVFDAEQEDEVTPEKLLEQLSISRDEKEQ
                     QNVPVQQQQQGQTKKRRNRQKERLAKRDAAIAKMKEEAALEASKQPDLKKMEQESIDQ
                     LCELKKLKQFDIQPDGHCLFASILDQLKLRHDPKKLDQDMDVMKLRWLSCNYVQEHRD
                     DFIPYLFDEETMKMKDIDEYTKEMEHTAQWGGEIEILALSHVFDCPISILMSGRPIQV
                     YNECGKNPELKLVYYKHSYALGEHYNSLHDS"
     gene            <78936..>80417
                     /locus_tag="YHL012W"
                     /db_xref="GeneID:856374"
     mRNA            <78936..>80417
                     /locus_tag="YHL012W"
                     /product="UTP--glucose-1-phosphate uridylyltransferase"
                     /transcript_id="NM_001179092.1"
                     /db_xref="GI:296145358"
                     /db_xref="GeneID:856374"
     CDS             78936..80417
                     /locus_tag="YHL012W"
                     /EC_number="2.7.7.9"
                     /note="Putative UTP glucose-1-phosphate
                     uridylyltransferase; YHL012W has a paralog, UGP1, that
                     arose from the whole genome duplication"
                     /codon_start=1
                     /product="UTP--glucose-1-phosphate uridylyltransferase"
                     /protein_id="NP_011851.1"
                     /db_xref="GI:6321775"
                     /db_xref="SGD:S000001004"
                     /db_xref="GeneID:856374"
                     /translation="MTVFSGVNKIEFEGTFEGIGKDVVMSQMIRALQKHFPSIRDKNY
                     EFSLFLHIFQRYVLENTSITHDLVCDKIRLPIIDEVVELDDIKNYGLLEGKLLSKLAI
                     LKLTGKANPIIGKESPLFEVKNGMSSLDVIVRQTQNLNVRYNSDVPLIFMTSLETESQ
                     VSNFLEEHYSSSKVRWKTVVQSSFPQIDKDRLLPIDLQINSHENDFWYPCGTGNLTDT
                     LYFSGELDKLIAQGKEILFVSNVDNLGATGDLNILNFIINEKIEYLVEVVERTANVSN
                     TGVLATYKGKLRSVYYNCLSNESASTCRIVNTNNIWIDLKKLKVLIESNSLNLPIHSS
                     ESKITHKNEEIECLQFKTQLVDCIAFFPNSRVLKVSRDRFLPLRTCKDLFLLKSTLYD
                     LDSNGTFNLYPLKFGLLPSIDLGDEFATYETFKIGVPDIPNILELEHLTVMGNVFFGR
                     NITLKGTVIIICDENDVITVPDGSILENVTIWHKSQLEDMNGY"
     gene            complement(<80654..>81616)
                     /gene="PRS3"
                     /locus_tag="YHL011C"
                     /db_xref="GeneID:856375"
     mRNA            complement(<80654..>81616)
                     /gene="PRS3"
                     /locus_tag="YHL011C"
                     /product="ribose phosphate diphosphokinase subunit PRS3"
                     /transcript_id="NM_001179091.1"
                     /db_xref="GI:296145359"
                     /db_xref="GeneID:856375"
     CDS             complement(80654..81616)
                     /gene="PRS3"
                     /locus_tag="YHL011C"
                     /EC_number="2.7.6.1"
                     /note="5-phospho-ribosyl-1(alpha)-pyrophosphate
                     synthetase; synthesizes PRPP, which is required for
                     nucleotide, histidine, and tryptophan biosynthesis; one of
                     five related enzymes, which are active as heteromultimeric
                     complexes"
                     /codon_start=1
                     /product="ribose phosphate diphosphokinase subunit PRS3"
                     /protein_id="NP_011852.1"
                     /db_xref="GI:6321776"
                     /db_xref="SGD:S000001003"
                     /db_xref="GeneID:856375"
                     /translation="MPTNSIKLLAPDVHRGLAELVAKRLGLQLTSSKLKRDPTGEVSF
                     SIGESVRDQDIFIITQIGSGVVNDRVLELLIMINASKTASARRITAIIPNFPYARQDR
                     KDKSRAPITAKLMADMLTTAGCDHVITMDLHASQIQGFFDVPVDNLYAEPSVVRYIKE
                     NVNYMDSIIISPDAGGAKRAATLADRLDLNFALIHKERARANEVSRMVLVGDVTDKIC
                     IIVDDMADTCGTLAKAAEILLENRAKSVIAIVTHGVLSGRAIENINNSKLDRVVCTNT
                     VPFEEKIKKCPKLAVIDISSVLAESIRRLHNGESISYLFKNYPL"
     gene            complement(<81964..>83721)
                     /gene="ETP1"
                     /locus_tag="YHL010C"
                     /db_xref="GeneID:856376"
     mRNA            complement(<81964..>83721)
                     /gene="ETP1"
                     /locus_tag="YHL010C"
                     /product="Etp1p"
                     /transcript_id="NM_001179090.1"
                     /db_xref="GI:296145360"
                     /db_xref="GeneID:856376"
     CDS             complement(81964..83721)
                     /gene="ETP1"
                     /locus_tag="YHL010C"
                     /note="hypothetical protein required for growth on
                     ethanol; contains a zinc finger region and has homology to
                     human BRAP2, which is a cytoplasmic protein that binds
                     nuclear localization sequences"
                     /codon_start=1
                     /product="Etp1p"
                     /protein_id="NP_011853.1"
                     /db_xref="GI:6321777"
                     /db_xref="SGD:S000001002"
                     /db_xref="GeneID:856376"
                     /translation="MDQFEYIITLEFGNQNQVESAYQIFKSIPKKLKAKSIGEESIKS
                     NNQDWQDWRVCDLEIDMITDFKNQTSKEEESDLITSQYLGHGIIRLFKLSNANNTLNE
                     KEILTIPGDDTMICILFVPTYFTVHDLLHFYIGDDIVNKQVSNFRILRNQQKGMGFNF
                     TVLIKFRNALDAKNFKEEFNGKSFSRMDPETCHVISVKEIVFQKKLFQRPAANEDFPY
                     LLTDPFTVKKKKELVKVELPTCPVCLERMDSETTGLVTIPCQHTFHCQCLNKWKNSRC
                     PVCRHSSLRLSRESLLKQAGDSAHCATCGSTDNLWICLICGNVGCGRYNSKHAIKHYE
                     ETLHCFAMDIRTQRVWDYAGDNYVHRLVQNEVDGKLVEVGGSGDDDNNDIGNSDELQN
                     VVYGNRSKNGEKSNSNKKDGELAANFLRHREYHLEYVQVLISQLESQREYYELKLQEK
                     DQTASDSSNVESLKKSMEDLKLQFQVTQKEWQKREMAQKSKLEEDMLVIEGLQANLDH
                     LSKKQEQLERENKALEESKQDLEEQVKDLMFYLDSQEKFKDADESVKEGTILIQQPHG
                     AAQASKSKKKRNKNKKAGK"
     gene            complement(<84068..>85060)
                     /gene="YAP3"
                     /locus_tag="YHL009C"
                     /db_xref="GeneID:856377"
     mRNA            complement(<84068..>85060)
                     /gene="YAP3"
                     /locus_tag="YHL009C"
                     /product="Yap3p"
                     /transcript_id="NM_001179089.1"
                     /db_xref="GI:296145361"
                     /db_xref="GeneID:856377"
     CDS             complement(84068..85060)
                     /gene="YAP3"
                     /locus_tag="YHL009C"
                     /note="Basic leucine zipper (bZIP) transcription factor"
                     /codon_start=1
                     /product="Yap3p"
                     /protein_id="NP_011854.1"
                     /db_xref="GI:6321778"
                     /db_xref="SGD:S000001001"
                     /db_xref="GeneID:856377"
                     /translation="MTPSNMDDNTSGFMKFINPQCQEEDCCIRNSLFQEDSKCIKQQP
                     DLLSEQTAPFPILEDQCPALNLDRSNNDLLLQNNISFPKGSDLQAIQLTPISGDYSTY
                     VMADNNNNDNDSYSNTNYFSKNNGISPSSRSPSVAHNENVPDDSKAKKKAQNRAAQKA
                     FRERKEARMKELQDKLLESERNRQSLLKEIEELRKANTEINAENRLLLRSGNENFSKD
                     IEDDTNYKYSFPTKDEFFTSMVLESKLNHKGKYSLKDNEIMKRNTQYTDEAGRHVLTV
                     PATWEYLYKLSEERDFDVTYVMSKLQGQECCHTHGPAYPRSLIDFLVEEATLNE"
     gene            complement(85298..85371)
                     /locus_tag="tV(AAC)H"
                     /db_xref="GeneID:856378"
     tRNA            complement(85298..85371)
                     /locus_tag="tV(AAC)H"
                     /product="tRNA-Val"
                     /note="Valine tRNA (tRNA-Val), predicted by tRNAscan-SE
                     analysis"
                     /db_xref="SGD:S000006758"
                     /db_xref="GeneID:856378"
     LTR             complement(85388..85538)
                     /note="Ty3 LTR"
                     /db_xref="SGD:S000006987"
     mobile_element  85539..91761
                     /note="YHLWTy4-1; Ty4 element, LTR retrotransposon of the
                     Copia (Pseudoviridae) group; contains co-transcribed genes
                     TYA Gag and TYB Pol, encoding proteins involved in
                     structure and function of virus-like particles, flanked by
                     two direct repeats"
                     /mobile_element_type="retrotransposon:YHLWTy4-1"
                     /db_xref="SGD:S000006991"
     LTR             85539..85909
                     /note="Ty4 LTR"
                     /db_xref="SGD:S000006989"
     gene            <85909..>91318
                     /locus_tag="YHL009W-B"
                     /db_xref="GeneID:856380"
     mRNA            <85909..>91318
                     /locus_tag="YHL009W-B"
                     /product="gag-pol fusion protein"
                     /transcript_id="NM_001184404.2"
                     /db_xref="GI:757874314"
                     /db_xref="GeneID:856380"
     CDS             join(85909..86994,86996..91318)
                     /locus_tag="YHL009W-B"
                     /EC_number="3.1.26.4"
                     /EC_number="2.7.7.7"
                     /EC_number="2.7.7.49"
                     /EC_number="3.4.23.-"
                     /ribosomal_slippage
                     /note="Retrotransposon TYA Gag and TYB Pol genes;
                     transcribed/translated as one unit; polyprotein is
                     processed to make a nucleocapsid-like protein (Gag),
                     reverse transcriptase (RT), protease (PR), and integrase
                     (IN); similar to retroviral genes"
                     /codon_start=1
                     /product="gag-pol fusion protein"
                     /protein_id="NP_058133.1"
                     /db_xref="GI:7839180"
                     /db_xref="SGD:S000007372"
                     /db_xref="GeneID:856380"
                     /translation="MATPVRDETRNVIDDNISARIQSKVKTNDTVRQTPSSLRKVSIK
                     DEQVKQYQRNLNRFKTILNGLKAEEEKLSETDDIQMLAEKLLKLGETIDKVENRIVDL
                     VEKIQLLETNENNNILHEHIDATGTYYLFDTLTSTNKRFYPKDCVFDYRTNNVENIPI
                     LLNNFKKFIKKYQFDDVFENDIIEIDPRENEILCKIIKEGLGESLDIMNTNTTDIFRI
                     IDGLKNKYRSLHGRDVRIRAWEKVLVDTTCRNSALLMNKLQKLVLMEKWIFSKCCQDC
                     PNLKDYLQEAIMGTLHESLRNSVKQRLYNIPHNVGINHEEFLINTVIETVIDLSPIAD
                     DQIENSCMYCKSVFHCSINCKKKPNRELGLTRPISQKPIIYKVHRDNNNLSPVQNEQK
                     SWNKTQKKSNKVYNSKKLVIIDTGSGVNITNDKTLLHNYEDSNRSTRFFGIGKNSSVS
                     VKGYGYIKIKNGHNNTDNKCLLTYYVPEEESTIISCYDLAKKTKMVLSRKYTRLGNKI
                     IKIKTKIVNGVIHVKMNELIERPSDDSKINAIKPTSSPGFKLNKRSITLEDAHKRMGH
                     TGIQQIENSIKHNHYEESLDLIKEPNEFWCQTCKISKATKRNHYTGSMNNHSTDHEPG
                     SSWCMDIFGPVSSSNADTKRYMLIMVDNNTRYCMTSTHFNKNAETILAQIRKNIQYVE
                     TQFDRKVREINSDRGTEFTNDQIEEYFISKGIHHILTSTQDHAANGRAERYIRTIVTD
                     ATTLLRQSNLRVKFWEYAVTSATNIRNCLEHKSTGKLPLKAISRQPVTVRLMSFLPFG
                     EKGIIWNHNHKKLKPSGLPSIILCKDPNSYGYKFFIPSKNKIVTSDNYTIPNYTMDGR
                     VRNTQNIYKSHQFSSHNDNEEDQIETVTNLCEALENYEDDNKPITRLEDLFTEEELSQ
                     IDSNAKYPSPSNNLEGDLDYVFSDVEESGDYDVESELSTTNTSISTDKNKILSNKDFN
                     SELASTEISISEIDKKGLINTSHIDEDKYDEKVHRIPSIIQEKLVGSKNTIKINDENR
                     ISDRIRSKNIGSILNTGLSRCVDITDESITNKDESMHNAKPELIQEQFNKTNHETSFP
                     KEGSIGTNVKFRNTDNEISLKTGDTSLPIKTLESINNHHSNDYSTNKVEKFEKENHHP
                     PPIEDIVDMSDQTDMESNCQDGNNLKELKVTDKNVPTDNGTNVSPRLEQNIEASGSPV
                     QTVNKSAFLNKEFSSLNMKRKRKRHDKNNSLTSYELERDKKRSKRNRVKLIPDNMETV
                     SAQKIRAIYYNEAISKNPDLKEKHEYKQAYHKELQNLKDMKVFDVDVKYSRSEIPDNL
                     IVPTNTIFTKKRNGIYKARIVCRGDTQSPDTYSVITTESLNHNHIKIFLMIANNRNMF
                     MKTLDINHAFLYAKLEEEIYIPHPHDRRCVVKLNKALYGLKQSPKEWNDHLRQYLNGI
                     GLKDNSYTPGLYQTEDKNLMIAVYVDDCVIAASNEQRLDEFINKLKSNFELKITGTLI
                     DDVLDTDILGMDLVYNKRLGTIDLTLKSFINRMDKKYNEELKKIRKSSIPHMSTYKID
                     PKKDVLQMSEEEFRQGVLKLQQLLGELNYVRHKCRYDINFAVKKVARLVNYPHERVFY
                     MIYKIIQYLVRYKDIGIHYDRDCNKDKKVIAITDASVGSEYDAQSRIGVILWYGMNIF
                     NVYSNKSTNRCVSSTEAELHAIYEGYADSETLKVTLKELGEGDNNDIVMITDSKPAIQ
                     GLNRSYQQPKEKFTWIKTEIIKEKIKEKSIKLLKITGKGNIADLLTKPVSASDFKRFI
                     QVLKNKITSQDILASTDY"
     gene            <85909..>87150
                     /locus_tag="YHL009W-A"
                     /db_xref="GeneID:856379"
     mRNA            <85909..>87150
                     /locus_tag="YHL009W-A"
                     /product="gag protein"
                     /transcript_id="NM_001184403.1"
                     /db_xref="GI:296145362"
                     /db_xref="GeneID:856379"
     CDS             85909..87150
                     /locus_tag="YHL009W-A"
                     /note="Retrotransposon TYA Gag gene co-transcribed with
                     TYB Pol; translated as TYA or TYA-TYB polyprotein; Gag is
                     a nucleocapsid protein that is the structural constituent
                     of virus-like particles (VLPs); similar to retroviral Gag"
                     /codon_start=1
                     /product="gag protein"
                     /protein_id="NP_058134.1"
                     /db_xref="GI:7839179"
                     /db_xref="SGD:S000007371"
                     /db_xref="GeneID:856379"
                     /translation="MATPVRDETRNVIDDNISARIQSKVKTNDTVRQTPSSLRKVSIK
                     DEQVKQYQRNLNRFKTILNGLKAEEEKLSETDDIQMLAEKLLKLGETIDKVENRIVDL
                     VEKIQLLETNENNNILHEHIDATGTYYLFDTLTSTNKRFYPKDCVFDYRTNNVENIPI
                     LLNNFKKFIKKYQFDDVFENDIIEIDPRENEILCKIIKEGLGESLDIMNTNTTDIFRI
                     IDGLKNKYRSLHGRDVRIRAWEKVLVDTTCRNSALLMNKLQKLVLMEKWIFSKCCQDC
                     PNLKDYLQEAIMGTLHESLRNSVKQRLYNIPHNVGINHEEFLINTVIETVIDLSPIAD
                     DQIENSCMYCKSVFHCSINCKKKPNRELRPDSTNFSKTYYLQGAQRQQQLKSSAKRTK
                     VLEQDTKKVKQSVQQQKTGNY"
     LTR             91391..91761
                     /note="Ty4 LTR"
                     /db_xref="SGD:S000006990"
     LTR             complement(91772..92099)
                     /note="Ty1 LTR"
                     /db_xref="SGD:S000006985"
     LTR             92240..92390
                     /note="Ty1 LTR"
                     /db_xref="SGD:S000006988"
     gene            complement(<92627..>94510)
                     /locus_tag="YHL008C"
                     /db_xref="GeneID:856381"
     mRNA            complement(<92627..>94510)
                     /locus_tag="YHL008C"
                     /product="hypothetical protein"
                     /transcript_id="NM_001179088.1"
                     /db_xref="GI:296145364"
                     /db_xref="GeneID:856381"
     CDS             complement(92627..94510)
                     /locus_tag="YHL008C"
                     /note="hypothetical protein; may be involved in the uptake
                     of chloride ions; does not appear to be involved in
                     monocarboxylic acid transport; green fluorescent protein
                     (GFP)-fusion protein localizes to the vacuole"
                     /codon_start=1
                     /product="hypothetical protein"
                     /protein_id="NP_011855.1"
                     /db_xref="GI:6321779"
                     /db_xref="SGD:S000001000"
                     /db_xref="GeneID:856381"
                     /translation="MVDDSNYLTPHETALAVVATAMKKARLQLDTLLINSILGGVLFS
                     SGSFLLVAVYSEDPDIVARNPGIVNLITGVNFAMGLFYVVMMGADLFNSNILFFSVGV
                     LRKAVTIYDLMISWVVSWLGNIAGSLFVSYLFGHLSGISSQKLWIIGSRQIIEQKVSY
                     SFVQTFLKGIACNFFVCLAIYLQLMAKPIHVKFILMSFPIIDFIGIGFTHVVGDMSAS
                     FIAMLNGANVSVGKYIWKLLIPASLGNIVGGLFFSAVVPFYLHLVVVERDRKRLSLPE
                     YEARDEQPELNMDSRVVRIQKNECDDDATETGEDLENLTEKGFASIYNTNHDNSSYFT
                     GRSLNSLRSIPSSVITSDNVTMESDLGEPVQFIPKSNSTTRSPHLGLPHNLPHNHSIK
                     SINRHRINKRHSLRSPPGVFPVRGMGEPLEREKTIEDATYDPKENELFLRRAETHNSA
                     YVKNKKKEDDNLLRLVKTEEDREQKEYEKNGGYNILENKPGTRLEKIITHLAENVSSR
                     EVTPPILPRTTQDTFPHNAPASSPAYTDDAHSLRKANSTTLGGLFRAVSKEFHSSKDA
                     ESPDDLLKKMAAVGINRNARITANNVAGIVNLNKEDLDSTTRRQKITEPKNFYNRHTS
                     PQL"
     gene            complement(<95118..>97937)
                     /gene="STE20"
                     /locus_tag="YHL007C"
                     /db_xref="GeneID:856382"
     mRNA            complement(<95118..>97937)
                     /gene="STE20"
                     /locus_tag="YHL007C"
                     /product="mitogen-activated protein kinase kinase kinase
                     kinase STE20"
                     /transcript_id="NM_001179087.1"
                     /db_xref="GI:296145365"
                     /db_xref="GeneID:856382"
     CDS             complement(95118..97937)
                     /gene="STE20"
                     /locus_tag="YHL007C"
                     /EC_number="2.7.11.1"
                     /EC_number="2.7.11.25"
                     /note="Cdc42p-activated signal transducing kinase;
                     involved in pheromone response, pseudohyphal/invasive
                     growth, vacuole inheritance, down-regulation of sterol
                     uptake; GBB motif binds Ste4p; member of the PAK
                     (p21-activated kinase) family"
                     /codon_start=1
                     /product="mitogen-activated protein kinase kinase kinase
                     kinase STE20"
                     /protein_id="NP_011856.1"
                     /db_xref="GI:6321780"
                     /db_xref="SGD:S000000999"
                     /db_xref="GeneID:856382"
                     /translation="MSNDPSAVSELPDKDSLDNGISNDNERAMGGNGDGGDGLRLPRT
                     TGTLNVNALQKGTNAAHEAGGYKSMDPAKNAETTNDDDNNVVSLDDPIQFTRVSSSSV
                     ISGMSSSMSPHSNIDETKSLEAVTPNINTSNITPDHSADNTFSTINASESDHQFNDTL
                     LSKLSLTDSTETIENNATVKHQQPVASSTVNSNKSSTDIRRATPVSTPVISKPSMTTT
                     PRQINSASHSLSNPKHKQHKPKVKPSKPEAKSKPVSVKKSFPSKNPLKNSSPPKKQTE
                     KSYYSSSSKKRKSGSNSGTLRMKDVFTSFVQNIKRNSQDDKRASSSSNNSSSSSITTA
                     LRISTPYNAKHIHHVGVDSKTGEYTGLPEEWEKLLTSSGISKREQQQNMQAVMDIVKF
                     YQDVTETNGEDKMFKTFNTTTGLPGSPQVSTPPANSFNKFPPSTSDSHNYGSRTGTPM
                     SNHVMSPTLNTDSSSANGKFIPSRPAPKPPSSASASAPIIKSPVMNSAANVSPLKQTH
                     APTTPNRTSPNRSSISRNATLKKEEQPLPPIPPTKSKTSPIISTAHTPQQVAQSPKAP
                     AQETVTTPTSKPAQARSLSKELNEKKREERERRKKQLYAKLNEICSDGDPSTKYANLV
                     KIGQGASGGVYTAYEIGTNVSVAIKQMNLEKQPKKELIINEILVMKGSKHPNIVNFID
                     SYVLKGDLWVIMEYMEGGSLTDVVTHCILTEGQIGAVCRETLSGLEFLHSKGVLHRDI
                     KSDNILLSMEGDIKLTDFGFCAQINELNLKRTTMVGTPYWMAPEVVSRKEYGPKVDIW
                     SLGIMIIEMIEGEPPYLNETPLRALYLIATNGTPKLKEPENLSSSLKKFLDWCLCVEP
                     EDRASATELLHDEYITEIAEANSSLAPLVKLARLKKVAENMDADEDNDDDNDNEHINK
                     TNNCDDNNDSKETVNLDVTEDDKQK"
     gene            complement(<98343..>98795)
                     /gene="SHU1"
                     /locus_tag="YHL006C"
                     /db_xref="GeneID:856383"
     mRNA            complement(<98343..>98795)
                     /gene="SHU1"
                     /locus_tag="YHL006C"
                     /product="Shu1p"
                     /transcript_id="NM_001179086.1"
                     /db_xref="GI:296145366"
                     /db_xref="GeneID:856383"
     CDS             complement(98343..98795)
                     /gene="SHU1"
                     /locus_tag="YHL006C"
                     /note="Component of Shu complex (aka PCSS complex); Shu
                     complex also includes Psy3, Csm2, Shu2, and promotes
                     error-free DNA repair, mediates inhibition of Srs2p
                     function; essential for promoting the establishment of
                     homolog bias during meiotic homologous recombination;
                     promotes both crossover (CO) and non-crossover (NCO)
                     pathways of meiotic recombination and formation of Rad51p
                     filaments"
                     /codon_start=1
                     /product="Shu1p"
                     /protein_id="NP_011857.2"
                     /db_xref="GI:41629684"
                     /db_xref="SGD:S000000998"
                     /db_xref="GeneID:856383"
                     /translation="MQFEERLQQLVESDWSLDQSSPNVLVIVLGDTARKYVELGGLKE
                     HVTTNTVAGHVASRERVSVVFLGRVKYLYMYLTRMQAQANGPQYSNVLVYGLWDLTAT
                     QDGPQQLRLLSLVLRQCLSLPSKVEFYPEPPSSSVPARLLRFWDHIIR"
     gene            <99219..>100403
                     /gene="MRP4"
                     /locus_tag="YHL004W"
                     /db_xref="GeneID:856384"
     mRNA            <99219..>100403
                     /gene="MRP4"
                     /locus_tag="YHL004W"
                     /product="mitochondrial 37S ribosomal protein MRP4"
                     /transcript_id="NM_001179084.1"
                     /db_xref="GI:296145367"
                     /db_xref="GeneID:856384"
     CDS             99219..100403
                     /gene="MRP4"
                     /locus_tag="YHL004W"
                     /note="Mitochondrial ribosomal protein of the small
                     subunit"
                     /codon_start=1
                     /product="mitochondrial 37S ribosomal protein MRP4"
                     /protein_id="NP_011859.1"
                     /db_xref="GI:6321782"
                     /db_xref="SGD:S000000996"
                     /db_xref="GeneID:856384"
                     /translation="MQRHVFARNFRRLSLLRNPSLTKRFQSSASGAANTPNNNDEVML
                     LQQKLLYDEIRSELKSLSQVPEDEILPELKKSLEQDKLSDKEQQLEAELSDFFRNYAL
                     LNKLFDSKTLDGQSSTTTAAATPTKPYPNLIPSANDKPYSSQELFLRQLNHSMRTAKL
                     GATISKVYYPHKDIFYPPLPENITVESLMSAGVHLGQSTSLWRSSTQSYIYGEYKGIH
                     IIDLNQTLSYLKRAAKVVEGVSESGGIILFLGTRQGQKRGLEEAAKKTHGYYVSTRWI
                     PGTLTNSTEISGIWEKQEIDSNDNPTERALSPNETSKQVKPDLLVVLNPTENRNALLE
                     AIKSRVPTIAIIDTDSEPSLVTYPIPGNDDSLRSVNFLLGVLARAGQRGLQNRLARNN
                     EK"
     gene            complement(<100648..>101883)
                     /gene="LAG1"
                     /locus_tag="YHL003C"
                     /db_xref="GeneID:856386"
     mRNA            complement(<100648..>101883)
                     /gene="LAG1"
                     /locus_tag="YHL003C"
                     /product="sphingosine N-acyltransferase LAG1"
                     /transcript_id="NM_001179083.1"
                     /db_xref="GI:296145368"
                     /db_xref="GeneID:856386"
     CDS             complement(100648..101883)
                     /gene="LAG1"
                     /locus_tag="YHL003C"
                     /EC_number="2.3.1.24"
                     /note="Ceramide synthase component; involved in synthesis
                     of ceramide from C26(acyl)-coenzyme A and
                     dihydrosphingosine or phytosphingosine, functionally
                     equivalent to Lac1p; forms ER foci upon DNA replication
                     stress; homolog of human CERS2, a tumor metastasis
                     suppressor gene whose silencing enahnces
                     invasion/metastasis of prostate cancer cells; LAG1 has a
                     paralog, LAC1, that arose from the whole genome
                     duplication"
                     /codon_start=1
                     /product="sphingosine N-acyltransferase LAG1"
                     /protein_id="NP_011860.1"
                     /db_xref="GI:6321784"
                     /db_xref="SGD:S000000995"
                     /db_xref="GeneID:856386"
                     /translation="MTSATDKSIDRLVVNAKTRRRNSSVGKIDLGDTVPGFAAMPESA
                     ASKNEAKKRMKALTGDSKKDSDLLWKVWFSYREMNYRHSWLTPFFILVCVYSAYFLSG
                     NRTESNPLHMFVAISYQVDGTDSYAKGIKDLSFVFFYMIFFTFLREFLMDVVIRPFTV
                     YLNVTSEHRQKRMLEQMYAIFYCGVSGPFGLYIMYHSDLWLFKTKPMYRTYPVITNPF
                     LFKIFYLGQAAFWAQQACVLVLQLEKPRKDYKELVFHHIVTLLLIWSSYVFHFTKMGL
                     AIYITMDVSDFFLSLSKTLNYLNSVFTPFVFGLFVFFWIYLRHVVNIRILWSVLTEFR
                     HEGNYVLNFATQQYKCWISLPIVFVLIAALQLVNLYWLFLILRILYRLIWQGIQKDER
                     SDSDSDESAENEESKEKCE"
     gene            <102612..>103970
                     /gene="HSE1"
                     /locus_tag="YHL002W"
                     /db_xref="GeneID:856387"
     mRNA            <102612..>103970
                     /gene="HSE1"
                     /locus_tag="YHL002W"
                     /product="ESCRT-0 subunit protein HSE1"
                     /transcript_id="NM_001179082.1"
                     /db_xref="GI:296145369"
                     /db_xref="GeneID:856387"
     CDS             102612..103970
                     /gene="HSE1"
                     /locus_tag="YHL002W"
                     /note="Subunit of the endosomal Vps27p-Hse1p complex;
                     complex is required for sorting of ubiquitinated membrane
                     proteins into intralumenal vesicles prior to vacuolar
                     degradation, as well as for recycling of Golgi proteins
                     and formation of lumenal membranes"
                     /codon_start=1
                     /product="ESCRT-0 subunit protein HSE1"
                     /protein_id="NP_011861.1"
                     /db_xref="GI:6321785"
                     /db_xref="SGD:S000000994"
                     /db_xref="GeneID:856387"
                     /translation="MSSSAIKIRNALLKATDPKLRSDNWQYILDVCDLVKEDPEDNGQ
                     EVMSLIEKRLEQQDANVILRTLSLTVSLAENCGSRLRQEISSKNFTSLLYALIESHSV
                     HITLKKAVTDVVKQLSDSFKDDPSLRAMGDLYDKIKRKAPYLVQPNVPEKHNMSTQAD
                     NSDDEELQKALKMSLFEYEKQKKLQEQEKESAEVLPQQQQQHQQQNQAPAHKIPAQTV
                     VRRVRALYDLTTNEPDELSFRKGDVITVLEQVYRDWWKGALRGNMGIFPLNYVTPIVE
                     PSKEEIEKEKNKEAIVFSQKTTIDQLHNSLNAASKTGNSNEVLQDPHIGDMYGSVTPL
                     RPQVTRMLGKYAKEKEDMLSLRQVLANAERSYNQLMDRAANAHISPPVPGPALYAGMT
                     HANNTPVMPPQRQSYQSNEYSPYPSNLPIQHPTNSANNTPQYGYDLGYSVVSQPPPGY
                     EQ"
     gene            <104277..>105091
                     /gene="RPL14B"
                     /locus_tag="YHL001W"
                     /db_xref="GeneID:856388"
     mRNA            join(<104277..104405,104804..>105091)
                     /gene="RPL14B"
                     /locus_tag="YHL001W"
                     /product="ribosomal 60S subunit protein L14B"
                     /transcript_id="NM_001179081.1"
                     /db_xref="GI:296145370"
                     /db_xref="GeneID:856388"
     CDS             join(104277..104405,104804..105091)
                     /gene="RPL14B"
                     /locus_tag="YHL001W"
                     /note="Ribosomal 60S subunit protein L14B; homologous to
                     mammalian ribosomal protein L14, no bacterial homolog;
                     RPL14B has a paralog, RPL14A, that arose from the whole
                     genome duplication; protein abundance increases in
                     response to DNA replication stress"
                     /codon_start=1
                     /product="ribosomal 60S subunit protein L14B"
                     /protein_id="NP_011862.1"
                     /db_xref="GI:6321786"
                     /db_xref="SGD:S000000993"
                     /db_xref="GeneID:856388"
                     /translation="MSTDSIVKASNWRLVEVGRVVLIKKGQSAGKLAAIVEIIDQKKV
                     LIDGPKAGVPRQAINLGQVVLTPLTFALPRGARTATVSKKWAAAGVCEKWAASSWAKK
                     IAQRERRAALTDFERFQVMVLRKQKRYTVKKALAKA"
     centromere      complement(105586..105703)
                     /note="CEN8; Chromosome VIII centromere"
                     /db_xref="SGD:S000006469"
     centromere      complement(105586..105610)
                     /note="CEN8_CDEIII of CEN8"
     centromere      complement(105611..105693)
                     /note="CEN8_CDEII of CEN8"
     centromere      complement(105694..105703)
                     /note="CEN8_CDEI of CEN8"
     gene            <106055..>107368
                     /gene="OSH7"
                     /locus_tag="YHR001W"
                     /db_xref="GeneID:856389"
     mRNA            <106055..>107368
                     /gene="OSH7"
                     /locus_tag="YHR001W"
                     /product="oxysterol-binding protein related protein OSH7"
                     /transcript_id="NM_001179131.1"
                     /db_xref="GI:296145371"
                     /db_xref="GeneID:856389"
     CDS             106055..107368
                     /gene="OSH7"
                     /locus_tag="YHR001W"
                     /note="Oxysterol-binding protein; part of family with
                     seven members in S. cerevisiae; family members have
                     overlapping, redundant functions in sterol metabolism and
                     collectively perform a function essential for viability;
                     OSH7 has a paralog, OSH6, that arose from the whole genome
                     duplication"
                     /codon_start=1
                     /product="oxysterol-binding protein related protein OSH7"
                     /protein_id="NP_011863.1"
                     /db_xref="GI:6321787"
                     /db_xref="SGD:S000001043"
                     /db_xref="GeneID:856389"
                     /translation="MALNKLKNIPSLTNSSHSSINGIASNAANSKPSGADTDDIDEND
                     ESGQSILLNIISQLKPGCDLSRITLPTFILEKKSMLERITNQLQFPDVLLEAHSNKDG
                     LQRFVKVVAWYLAGWHIGPRAVKKPLNPILGEHFTAYWDLPNKQQAFYIAEQTSHHPP
                     ESAYFYMIPESNIRVDGVVVPKSKFLGNSSAAMMEGLTVLQFLDIKDANGKPEKYTLS
                     QPNVYARGILFGKMRIELGDHMVIMGPKYQVDIEFKTKGFISGTYDAIEGTIKDYDGK
                     EYYQISGKWNDIMYIKDLREKSSKKTVLFDTHQHFPLAPKVRPLEEQGEYESRRLWKK
                     VTDALAVRDHEVATEEKFQIENRQRELAKKRAEDGVEFHSKLFRRAEPGEDLDYYIYK
                     HIPEGTDKHEEQIRSILETAPILPGQTFTEKFSIPAYKKHGIQKN"
     gene            <107826..>108122
                     /gene="QCR10"
                     /locus_tag="YHR001W-A"
                     /db_xref="GeneID:856390"
     mRNA            join(<107826..107831,107895..>108122)
                     /gene="QCR10"
                     /locus_tag="YHR001W-A"
                     /product="ubiquinol--cytochrome-c reductase subunit 10"
                     /transcript_id="NM_001181426.1"
                     /db_xref="GI:296145372"
                     /db_xref="GeneID:856390"
     CDS             join(107826..107831,107895..108122)
                     /gene="QCR10"
                     /locus_tag="YHR001W-A"
                     /note="Subunit of the ubiqunol-cytochrome c oxidoreductase
                     complex; this complex comprises part of the mitochondrial
                     respiratory chain; members include Cobp, Rip1p, Cyt1p,
                     Cor1p, Qcr2p, Qcr6p, Qcr7p, Qcr8p, Qcr9p, and Qcr10p and
                     comprises part of the mitochondrial respiratory chain"
                     /codon_start=1
                     /product="ubiquinol--cytochrome-c reductase subunit 10"
                     /protein_id="NP_011864.1"
                     /db_xref="GI:6321788"
                     /db_xref="SGD:S000003529"
                     /db_xref="GeneID:856390"
                     /translation="MAYTSHLSSKTGLHFGRLSLRSLTAYAPNLMLWGGASMLGLFVF
                     TEGWPKFQDTLYKKIPLLGPTLEDHTPPEDKPN"
     gene            <108812..>109885
                     /gene="LEU5"
                     /locus_tag="YHR002W"
                     /db_xref="GeneID:856391"
     mRNA            <108812..>109885
                     /gene="LEU5"
                     /locus_tag="YHR002W"
                     /product="Leu5p"
                     /transcript_id="NM_001179132.1"
                     /db_xref="GI:296145373"
                     /db_xref="GeneID:856391"
     CDS             108812..109885
                     /gene="LEU5"
                     /locus_tag="YHR002W"
                     /note="Mitochondrial carrier protein; involved in the
                     accumulation of CoA in the mitochondrial matrix; homolog
                     of human Graves disease protein; does not encode an
                     isozyme of Leu4p, as first hypothesized"
                     /codon_start=1
                     /product="Leu5p"
                     /protein_id="NP_011865.1"
                     /db_xref="GI:6321789"
                     /db_xref="SGD:S000001044"
                     /db_xref="GeneID:856391"
                     /translation="MTRDSPDSNDSYKHINKNTTQKTSFDRNSFDYIVRSGLAGGISG
                     SCAKTLIAPLDRIKILFQTSNPHYTKYTGSLIGLVEAAKHIWINDGVRGFFQGHSATL
                     LRIFPYAAVKFVAYEQIRNTLIPSKEFESHWRRLVSGSLAGLCSVFITYPLDLVRVRL
                     AYETEHKRVKLGRIIKKIYKEPASATLIKNDYIPNWFCHWCNFYRGYVPTVLGMIPYA
                     GVSFFAHDLLHDVLKSPFFAPYSVLELSEDDELERVQKKQRRPLRTWAELISGGLAGM
                     ASQTAAYPFEIIRRRLQVSALSPKTMYDHKFQSISEIAHIIFKERGVRGFFVGLSIGY
                     IKVTPMVACSFFVYERMKWNFGI"
     gene            complement(<110028..>111317)
                     /gene="TCD1"
                     /locus_tag="YHR003C"
                     /db_xref="GeneID:856392"
     mRNA            complement(<110028..>111317)
                     /gene="TCD1"
                     /locus_tag="YHR003C"
                     /product="Tcd1p"
                     /transcript_id="NM_001179133.1"
                     /db_xref="GI:296145374"
                     /db_xref="GeneID:856392"
     CDS             complement(110028..111317)
                     /gene="TCD1"
                     /locus_tag="YHR003C"
                     /EC_number="6.1.-.-"
                     /note="tRNA threonylcarbamoyladenosine dehydratase;
                     required for the ct6A tRNA base modification, where an
                     adenosine at position 37 is modified to form a cyclized
                     active ester with an oxazolone ring; localized to the
                     mitochondrial outer membrane; TCD1 has a paralog, TCD2,
                     that arose from the whole genome duplication"
                     /codon_start=1
                     /product="Tcd1p"
                     /protein_id="NP_011866.1"
                     /db_xref="GI:6321790"
                     /db_xref="SGD:S000001045"
                     /db_xref="GeneID:856392"
                     /translation="MANNTWKLIATTALISVFSTQLAKSVWKEYKLSCAANKNKTVSR
                     PRQYDDHLFREQLARNYAFLGEEGMRKIKEQYIVIVGAGEVGSWVCTMLIRSGCQKIM
                     IIDPENISIDSLNTHCCAVLSDIGKPKVQCLKEHLSKIAPWSEIKARAKAWTKENSHD
                     LIFADGESPTFIVDCLDNLESKVDLLEYAHHNKIDVISSMGVATKSDPTRVSINDISM
                     TEFDPISRCVRRKLRKRGIATGISVVFSNEMLDPRRDDILSPIDCEHRAINAVRDEAL
                     RHLPELGTMPGIFGLSIATWILTKVSGYPMKENEVKNRLKFYDSILETFQKQMARLNE
                     NKERSSLLGLEEVGYIVEEMFRGKSPISGYSTKLALTKWEANKEISLTNVVLMTKEEQ
                     EIHEKRILLDGEKLTAVYSEEVLDFIERLFKEEEYYS"
     gene            complement(<111754..>113094)
                     /gene="NEM1"
                     /locus_tag="YHR004C"
                     /db_xref="GeneID:856393"
     mRNA            complement(<111754..>113094)
                     /gene="NEM1"
                     /locus_tag="YHR004C"
                     /product="Nem1-Spo7 phosphatase catalytic subunit NEM1"
                     /transcript_id="NM_001179134.1"
                     /db_xref="GI:296145375"
                     /db_xref="GeneID:856393"
     CDS             complement(111754..113094)
                     /gene="NEM1"
                     /locus_tag="YHR004C"
                     /EC_number="3.1.3.16"
                     /note="Probable catalytic subunit of Nem1p-Spo7p
                     phosphatase holoenzyme; regulates nuclear growth by
                     controlling phospholipid biosynthesis, required for normal
                     nuclear envelope morphology and sporulation; homolog of
                     the human protein Dullard"
                     /codon_start=1
                     /product="Nem1-Spo7 phosphatase catalytic subunit NEM1"
                     /protein_id="NP_011867.1"
                     /db_xref="GI:6321791"
                     /db_xref="SGD:S000001046"
                     /db_xref="GeneID:856393"
                     /translation="MNALKYFSNHLITTKKQKKINVEVTKNQDLLGPSKEVSNKYTSH
                     SENDCVSEVDQQYDHSSSHLKESDQNQERKNSVPKKPKALRSILIEKIASILWALLLF
                     LPYYLIIKPLMSLWFVFTFPLSVIERRVKHTDKRNRGSNASENELPVSSSNINDSSEK
                     TNPKNCNLNTIPEAVEDDLNASDEIILQRDNVKGSLLRAQSVKSRPRSYSKSELSLSN
                     HSSSNTVFGTKRMGRFLFPKKLIPKSVLNTQKKKKLVIDLDETLIHSASRSTTHSNSS
                     QGHLVEVKFGLSGIRTLYFIHKRPYCDLFLTKVSKWYDLIIFTASMKEYADPVIDWLE
                     SSFPSSFSKRYYRSDCVLRDGVGYIKDLSIVKDSEENGKGSSSSLDDVIIIDNSPVSY
                     AMNVDNAIQVEGWISDPTDTDLLNLLPFLEAMRYSTDVRNILALKHGEKAFNIN"
     gene            complement(<113499..>114917)
                     /gene="GPA1"
                     /locus_tag="YHR005C"
                     /gene_synonym="CDC70; DAC1; SCG1"
                     /db_xref="GeneID:856394"
     mRNA            complement(<113499..>114917)
                     /gene="GPA1"
                     /locus_tag="YHR005C"
                     /gene_synonym="CDC70; DAC1; SCG1"
                     /product="guanine nucleotide-binding protein subunit
                     alpha"
                     /transcript_id="NM_001179135.1"
                     /db_xref="GI:296145376"
                     /db_xref="GeneID:856394"
     CDS             complement(113499..114917)
                     /gene="GPA1"
                     /locus_tag="YHR005C"
                     /gene_synonym="CDC70; DAC1; SCG1"
                     /note="Subunit of the G protein involved in pheromone
                     response; GTP-binding alpha subunit of the heterotrimeric
                     G protein; negatively regulates the mating pathway by
                     sequestering G(beta)gamma and by triggering an adaptive
                     response; activates Vps34p at the endosome; protein
                     abundance increases in response to DNA replication stress"
                     /codon_start=1
                     /product="guanine nucleotide-binding protein subunit
                     alpha"
                     /protein_id="NP_011868.1"
                     /db_xref="GI:6321792"
                     /db_xref="SGD:S000001047"
                     /db_xref="GeneID:856394"
                     /translation="MGCTVSTQTIGDESDPFLQNKRANDVIEQSLQLEKQRDKNEIKL
                     LLLGAGESGKSTVLKQLKLLHQGGFSHQERLQYAQVIWADAIQSMKILIIQARKLGIQ
                     LDCDDPINNKDLFACKRILLKAKALDYINASVAGGSDFLNDYVLKYSERYETRRRVQS
                     TGRAKAAFDEDGNISNVKSDTDRDAETVTQNEDADRNNSSRINLQDICKDLNQEGDDQ
                     MFVRKTSREIQGQNRRNLIHEDIAKAIKQLWNNDKGIKQCFARSNEFQLEGSAAYYFD
                     NIEKFASPNYVCTDEDILKGRIKTTGITETEFNIGSSKFKVLDAGGQRSERKKWIHCF
                     EGITAVLFVLAMSEYDQMLFEDERVNRMHESIMLFDTLLNSKWFKDTPFILFLNKIDL
                     FEEKVKSMPIRKYFPDYQGRVGDAEAGLKYFEKIFLSLNKTNKPIYVKRTCATDTQTM
                     KFVLSAVTDLIIQQNLKKIGII"
     gene            complement(<115620..>115901)
                     /gene="TIM10"
                     /locus_tag="YHR005C-A"
                     /gene_synonym="MRS11"
                     /db_xref="GeneID:856395"
     mRNA            complement(<115620..>115901)
                     /gene="TIM10"
                     /locus_tag="YHR005C-A"
                     /gene_synonym="MRS11"
                     /product="protein transporter TIM10"
                     /transcript_id="NM_001181427.1"
                     /db_xref="GI:296145377"
                     /db_xref="GeneID:856395"
     CDS             complement(115620..115901)
                     /gene="TIM10"
                     /locus_tag="YHR005C-A"
                     /gene_synonym="MRS11"
                     /note="Essential protein of the mitochondrial
                     intermembrane space; forms a complex with Tim9p (TIM10
                     complex) that delivers hydrophobic proteins to the TIM22
                     complex for insertion into the inner membrane"
                     /codon_start=1
                     /product="protein transporter TIM10"
                     /protein_id="NP_011869.1"
                     /db_xref="GI:6321793"
                     /db_xref="SGD:S000003530"
                     /db_xref="GeneID:856395"
                     /translation="MSFLGFGGGQPQLSSQQKIQAAEAELDLVTDMFNKLVNNCYKKC
                     INTSYSEGELNKNESSCLDRCVAKYFETNVQVGENMQKMGQSFNAAGKF"
     gene            complement(116107..116179)
                     /locus_tag="tT(AGU)H"
                     /db_xref="GeneID:856396"
     tRNA            complement(116107..116179)
                     /locus_tag="tT(AGU)H"
                     /product="tRNA-Thr"
                     /note="Threonine tRNA (tRNA-Thr), predicted by tRNAscan-SE
                     analysis"
                     /db_xref="SGD:S000006740"
                     /db_xref="GeneID:856396"
     rep_origin      116179..116421
                     /note="ARS806;
                     Putative replication origin; identified in multiple array
                     studies, not yet confirmed by plasmid-based assay"
                     /db_xref="SGD:S000130146"
     LTR             complement(116421..116752)
                     /note="Ty1 LTR"
                     /db_xref="SGD:S000006992"
     LTR             complement(116763..117061)
                     /note="Ty1 LTR"
                     /db_xref="SGD:S000006993"
     gene            <117814..>119439
                     /gene="STP2"
                     /locus_tag="YHR006W"
                     /db_xref="GeneID:856397"
     mRNA            <117814..>119439
                     /gene="STP2"
                     /locus_tag="YHR006W"
                     /product="Stp2p"
                     /transcript_id="NM_001179136.1"
                     /db_xref="GI:296145378"
                     /db_xref="GeneID:856397"
     CDS             117814..119439
                     /gene="STP2"
                     /locus_tag="YHR006W"
                     /note="Transcription factor; activated by proteolytic
                     processing in response to signals from the SPS sensor
                     system for external amino acids; activates transcription
                     of amino acid permease genes; STP2 has a paralog, STP1,
                     that arose from the whole genome duplication"
                     /codon_start=1
                     /product="Stp2p"
                     /protein_id="NP_011870.1"
                     /db_xref="GI:6321794"
                     /db_xref="SGD:S000001048"
                     /db_xref="GeneID:856397"
                     /translation="MPILSLSSTRNSVLTRIYDYLKALVQQVIVPNVEDDKSSKSTPF
                     EKLEPAKQNHPQKDCCATEKDDLVDVSELFPKQNNKQLSLTSKSSVVPCALNLDNLET
                     PFSIKIDNNGAVTTQLNLDEPILRGPSRGEPAKLQNDLISSPPLEESYINNDQYKALF
                     PSNFLPITPVSSVITPASKKSIDESPLSDEVQGIADESSETLPYICHYCDARFRIRGY
                     LTRHIKKHAKRKAYHCPFFDNSISQELRCHTSGGFSRRDTYKTHLKSRHFTYPEGVKP
                     QDRNKSPGVCTQCGEHFSTSESWVENHIEAGSCKGLPEGYSEGIREKKKTSKMKMIKT
                     SDGQTRFISSDESVSEPALQNKNCIEATVMQSKERPNDKIIPTKTEKNDFGIGTQWFE
                     RKQISRPTQTTQSRGPTEVQNLKEWSIISPPILSPQNASSVPQEYQSSRYTLHMDSPA
                     LSSASSALSPLSGDPITTTETNKSYPLDSEQSLLEPDKTEEDAINQSKESNMISINEM
                     LQKQMDFELLGENHLKETQDYLALYKKAYGIEF"
     gene            complement(<120091..>121683)
                     /gene="ERG11"
                     /locus_tag="YHR007C"
                     /gene_synonym="CYP51"
                     /db_xref="GeneID:856398"
     mRNA            complement(<120091..>121683)
                     /gene="ERG11"
                     /locus_tag="YHR007C"
                     /gene_synonym="CYP51"
                     /product="sterol 14-demethylase"
                     /transcript_id="NM_001179137.1"
                     /db_xref="GI:296145379"
                     /db_xref="GeneID:856398"
     CDS             complement(120091..121683)
                     /gene="ERG11"
                     /locus_tag="YHR007C"
                     /gene_synonym="CYP51"
                     /EC_number="1.14.13.70"
                     /note="Lanosterol 14-alpha-demethylase; catalyzes the C-14
                     demethylation of lanosterol to form 4,4''-dimethyl
                     cholesta-8,14,24-triene-3-beta-ol in the ergosterol
                     biosynthesis pathway; member of the cytochrome P450
                     family; associated and coordinately regulated with the
                     P450 reductase Ncp1p"
                     /codon_start=1
                     /product="sterol 14-demethylase"
                     /protein_id="NP_011871.1"
                     /db_xref="GI:6321795"
                     /db_xref="SGD:S000001049"
                     /db_xref="GeneID:856398"
                     /translation="MSATKSIVGEALEYVNIGLSHFLALPLAQRISLIIIIPFIYNIV
                     WQLLYSLRKDRPPLVFYWIPWVGSAVVYGMKPYEFFEECQKKYGDIFSFVLLGRVMTV
                     YLGPKGHEFVFNAKLADVSAEAAYAHLTTPVFGKGVIYDCPNSRLMEQKKFVKGALTK
                     EAFKSYVPLIAEEVYKYFRDSKNFRLNERTTGTIDVMVTQPEMTIFTASRSLLGKEMR
                     AKLDTDFAYLYSDLDKGFTPINFVFPNLPLEHYRKRDHAQKAISGTYMSLIKERRKNN
                     DIQDRDLIDSLMKNSTYKDGVKMTDQEIANLLIGVLMGGQHTSAATSAWILLHLAERP
                     DVQQELYEEQMRVLDGGKKELTYDLLQEMPLLNQTIKETLRMHHPLHSLFRKVMKDMH
                     VPNTSYVIPAGYHVLVSPGYTHLRDEYFPNAHQFNIHRWNKDSASSYSVGEEVDYGFG
                     AISKGVSSPYLPFGGGRHRCIGEHFAYCQLGVLMSIFIRTLKWHYPEGKTVPPPDFTS
                     MVTLPTGPAKIIWEKRNPEQKI"
     gene            complement(<122550..>122765)
                     /locus_tag="YHR007C-A"
                     /db_xref="GeneID:1466526"
     mRNA            complement(<122550..>122765)
                     /locus_tag="YHR007C-A"
                     /product="hypothetical protein"
                     /transcript_id="NM_001184651.1"
                     /db_xref="GI:296145380"
                     /db_xref="GeneID:1466526"
     CDS             complement(122550..122765)
                     /locus_tag="YHR007C-A"
                     /note="hypothetical protein; identified by expression
                     profiling and mass spectrometry"
                     /codon_start=1
                     /product="hypothetical protein"
                     /protein_id="NP_878086.1"
                     /db_xref="GI:33438804"
                     /db_xref="SGD:S000028830"
                     /db_xref="GeneID:1466526"
                     /translation="MHRKKRKKEKKRTEKDNTTNLPPLFLFPCSLSLPTLLAPVHYIP
                     TRLTHHQAENQLFLLLFQPIIVKPLRS"
     gene            complement(<122889..>123590)
                     /gene="SOD2"
                     /locus_tag="YHR008C"
                     /db_xref="GeneID:856399"
     mRNA            complement(<122889..>123590)
                     /gene="SOD2"
                     /locus_tag="YHR008C"
                     /product="superoxide dismutase SOD2"
                     /transcript_id="NM_001179138.1"
                     /db_xref="GI:296145381"
                     /db_xref="GeneID:856399"
     CDS             complement(122889..123590)
                     /gene="SOD2"
                     /locus_tag="YHR008C"
                     /EC_number="1.15.1.1"
                     /note="Mitochondrial manganese superoxide dismutase;
                     protects cells against oxygen toxicity; phosphorylated"
                     /codon_start=1
                     /product="superoxide dismutase SOD2"
                     /protein_id="NP_011872.1"
                     /db_xref="GI:6321796"
                     /db_xref="SGD:S000001050"
                     /db_xref="GeneID:856399"
                     /translation="MFAKTAAANLTKKGGLSLLSTTARRTKVTLPDLKWDFGALEPYI
                     SGQINELHYTKHHQTYVNGFNTAVDQFQELSDLLAKEPSPANARKMIAIQQNIKFHGG
                     GFTNHCLFWENLAPESQGGGEPPTGALAKAIDEQFGSLDELIKLTNTKLAGVQGSGWA
                     FIVKNLSNGGKLDVVQTYNQDTVTGPLVPLVAIDAWEHAYYLQYQNKKADYFKAIWNV
                     VNWKEASRRFDAGKI"
     gene            complement(<124109..>125680)
                     /gene="TDA3"
                     /locus_tag="YHR009C"
                     /gene_synonym="BTN3"
                     /db_xref="GeneID:856400"
     mRNA            complement(<124109..>125680)
                     /gene="TDA3"
                     /locus_tag="YHR009C"
                     /gene_synonym="BTN3"
                     /product="Tda3p"
                     /transcript_id="NM_001179139.1"
                     /db_xref="GI:296145382"
                     /db_xref="GeneID:856400"
     CDS             complement(124109..125680)
                     /gene="TDA3"
                     /locus_tag="YHR009C"
                     /gene_synonym="BTN3"
                     /EC_number="1.-.-.-"
                     /note="Putative oxidoreductase involved in late endosome
                     to Golgi transport; physical and genetical interactions
                     with Btn2p; null mutant is viable, has extended S phase,
                     and sensitive to expression of top1-T722A allele; similar
                     to human FOXRED1"
                     /codon_start=1
                     /product="Tda3p"
                     /protein_id="NP_011873.1"
                     /db_xref="GI:6321797"
                     /db_xref="SGD:S000001051"
                     /db_xref="GeneID:856400"
                     /translation="MGEDFMHPPFQTYPSKNSEGKKHIVIVGGGIIGCCTAYYLTQHP
                     SFSPSTHHITIIESRRIAGGASGKAGGLLASWAFPHQIVPLSFQLHQELSDEYDGENN
                     WDYRRLTTVSLEADVREEVIENYERLSKKAYNLNVPPPKKRPGYISNKFNIGDSNSSL
                     SSSGSSLKNDSASNEEEGSDIHVSSSVPSLHSLTNERMRSHTNSASDLDSVSPVEQLR
                     ETNIHNPLPADLDWIRRELVNDWSSLGGTDTTAQLHPYKFTHFILSKAMETGAVDLLL
                     GKVVGLKCDEMDCVHSLKYLPSVVKNRRNSRGHAENPDIKLGTIFNDENAKPIEINDI
                     QQIVLSMGPWTSKILKDCPISGLRAHSVTIKPSEKTVSPYAILAELKVNDREFFSPEM
                     YARKDEVYVCGEGDTLVNIPESSDDVEVVSEKCDELYHYVSKLSPTLSKGHLLRKQAC
                     FLPVLNVPTSSGPLIGETNVKDLYIASGHSCWGINNAPATGKLMAEILLDGEATSAEI
                     SSLDPKLYFDATILS"
     gene            <126521..>127492
                     /gene="RPL27A"
                     /locus_tag="YHR010W"
                     /gene_synonym="RPL27"
                     /db_xref="GeneID:856401"
     mRNA            join(<126521..126551,127113..>127492)
                     /gene="RPL27A"
                     /locus_tag="YHR010W"
                     /gene_synonym="RPL27"
                     /product="ribosomal 60S subunit protein L27A"
                     /transcript_id="NM_001179140.1"
                     /db_xref="GI:296145383"
                     /db_xref="GeneID:856401"
     CDS             join(126521..126551,127113..127492)
                     /gene="RPL27A"
                     /locus_tag="YHR010W"
                     /gene_synonym="RPL27"
                     /note="Ribosomal 60S subunit protein L27A; homologous to
                     mammalian ribosomal protein L27, no bacterial homolog;
                     RPL27A has a paralog, RPL27B, that arose from the whole
                     genome duplication"
                     /codon_start=1
                     /product="ribosomal 60S subunit protein L27A"
                     /protein_id="NP_011874.1"
                     /db_xref="GI:6321798"
                     /db_xref="SGD:S000001052"
                     /db_xref="GeneID:856401"
                     /translation="MAKFLKAGKVAVVVRGRYAGKKVVIVKPHDEGSKSHPFGHALVA
                     GIERYPLKVTKKHGAKKVAKRTKIKPFIKVVNYNHLLPTRYTLDVEAFKSVVSTETFE
                     QPSQREEAKKVVKKAFEERHQAGKNQWFFSKLRF"
     gene            <127780..>129120
                     /gene="DIA4"
                     /locus_tag="YHR011W"
                     /db_xref="GeneID:856402"
     mRNA            <127780..>129120
                     /gene="DIA4"
                     /locus_tag="YHR011W"
                     /product="putative serine--tRNA ligase DIA4"
                     /transcript_id="NM_001179141.1"
                     /db_xref="GI:296145384"
                     /db_xref="GeneID:856402"
     CDS             127780..129120
                     /gene="DIA4"
                     /locus_tag="YHR011W"
                     /EC_number="6.1.1.11"
                     /note="Probable mitochondrial seryl-tRNA synthetase;
                     mutant displays increased invasive and pseudohyphal
                     growth"
                     /codon_start=1
                     /product="putative serine--tRNA ligase DIA4"
                     /protein_id="NP_011875.1"
                     /db_xref="GI:6321799"
                     /db_xref="SGD:S000001053"
                     /db_xref="GeneID:856402"
                     /translation="MIIRRLFSISNRSFFLKKPQFDVKKIIEMIPQYQTSIQNRELIE
                     ADSIIRSLQLLGERYQNIKEIDKVIADIQIQRKSIEAQIKKDKTKITEYSAALKALKE
                     QYNDQNSKSSELKKKILETCKSLPNTLDPTVPLDAPQIEQWINPLKTHKTSEAQAHVD
                     IMLKKNMLDLQTASNVTGMSWYYLLNDGARLEQALVAYALKKANENGFSSCVPPSITK
                     KELIDACGFNPRDMNNERQIYALQDTNLGLVATAEIPLAGLGANKVLELNSGECSKKL
                     VGVSRCYRAEAGARGKDTKGLYRVHEFTKVELFCWSKPETSAKVLEEIKQFQISVVEE
                     LGIPAKVLNMPSNDLGNPAFKKYDIEAWMPGRGKFGEISSASNCTDFQSRRLNTKYRD
                     DNTGKLEYVHTLNGTAMAIPRVIVALVENFYDPSTGKISVPECLREFMNGQRYI"
     gene            <129481..>130448
                     /gene="VPS29"
                     /locus_tag="YHR012W"
                     /gene_synonym="PEP11; VPT6"
                     /db_xref="GeneID:856403"
     mRNA            join(<129481..129528,129648..>130448)
                     /gene="VPS29"
                     /locus_tag="YHR012W"
                     /gene_synonym="PEP11; VPT6"
                     /product="Vps29p"
                     /transcript_id="NM_001179142.1"
                     /db_xref="GI:296145385"
                     /db_xref="GeneID:856403"
     CDS             join(129481..129528,129648..130448)
                     /gene="VPS29"
                     /locus_tag="YHR012W"
                     /gene_synonym="PEP11; VPT6"
                     /note="Subunit of the membrane-associated retromer
                     complex; endosomal protein; essential for
                     endosome-to-Golgi retrograde transport; forms a subcomplex
                     with Vps35p and Vps26p that selects cargo proteins for
                     endosome-to-Golgi retrieval"
                     /codon_start=1
                     /product="Vps29p"
                     /protein_id="NP_011876.1"
                     /db_xref="GI:6321800"
                     /db_xref="SGD:S000001054"
                     /db_xref="GeneID:856403"
                     /translation="MLLLALSDAHIPDRATDLPVKFKKLLSVPDKISQVALLGNSTKS
                     YDFLKFVNQISNNITIVRGEFDNGHLPSTKKDKASDNSRPMEEIPMNSIIRQGALKIG
                     CCSGYTVVPKNDPLSLLALARQLDVDILLWGGTHNVEAYTLEGKFFVNPGSCTGAFNT
                     DWPIVFDVEDSDEAVTSEVDKPTKENQSEDDDAKGGSTGKEQPGSYTPKEGTAGEREN
                     ENESNVKPENQFKEDEVDMSDSDINGSNSPSFCLLDIQGNTCTLYIYLYVNGEVKVDK
                     VVYEKE"
     gene            complement(<130730..>131446)
                     /gene="ARD1"
                     /locus_tag="YHR013C"
                     /gene_synonym="NAA10"
                     /db_xref="GeneID:856404"
     mRNA            complement(<130730..>131446)
                     /gene="ARD1"
                     /locus_tag="YHR013C"
                     /gene_synonym="NAA10"
                     /product="Ard1p"
                     /transcript_id="NM_001179143.1"
                     /db_xref="GI:296145386"
                     /db_xref="GeneID:856404"
     CDS             complement(130730..131446)
                     /gene="ARD1"
                     /locus_tag="YHR013C"
                     /gene_synonym="NAA10"
                     /EC_number="2.3.1.88"
                     /note="Subunit of protein N-terminal acetyltransferase
                     NatA; NatA is comprised of Nat1p, Ard1p, and Nat5p;
                     acetylates many proteins and thus affects telomeric
                     silencing, cell cycle, heat-shock resistance, mating, and
                     sporulation; human Ard1p levels are elevated in cancer
                     cells; protein abundance increases in response to DNA
                     replication stress"
                     /codon_start=1
                     /product="Ard1p"
                     /protein_id="NP_011877.1"
                     /db_xref="GI:6321801"
                     /db_xref="SGD:S000001055"
                     /db_xref="GeneID:856404"
                     /translation="MPINIRRATINDIICMQNANLHNLPENYMMKYYMYHILSWPEAS
                     FVATTTTLDCEDSDEQDENDKLELTLDGTNDGRTIKLDPTYLAPGEKLVGYVLVKMND
                     DPDQQNEPPNGHITSLSVMRTYRRMGIAENLMRQALFALREVHQAEYVSLHVRQSNRA
                     ALHLYRDTLAFEVLSIEKSYYQDGEDAYAMKKVLKLEELQISNFTHRRLKENEEKLED
                     DLESDLLEDIIKQGVNDIIV"
     gene            <132047..>132922
                     /gene="SPO13"
                     /locus_tag="YHR014W"
                     /db_xref="GeneID:856405"
     mRNA            <132047..>132922
                     /gene="SPO13"
                     /locus_tag="YHR014W"
                     /product="Spo13p"
                     /transcript_id="NM_001179144.1"
                     /db_xref="GI:296145387"
                     /db_xref="GeneID:856405"
     CDS             132047..132922
                     /gene="SPO13"
                     /locus_tag="YHR014W"
                     /note="Meiotic regulator; involved in maintaining sister
                     chromatid cohesion during meiosis I as well as promoting
                     proper attachment of kinetochores to the spindle during
                     meiosis I and meiosis II; anaphase-promoting complex (APC)
                     substrate that is degraded during anaphase I; expressed
                     only in meiotic cells"
                     /codon_start=1
                     /product="Spo13p"
                     /protein_id="NP_011878.1"
                     /db_xref="GI:6321802"
                     /db_xref="SGD:S000001056"
                     /db_xref="GeneID:856405"
                     /translation="MAPRKRFRLLELGSPTHSKRKVQKPLQEKTPNLRVSPLAFKIGK
                     EIKNKEIRKTKKTESENIFNSKHVDLRLESPHPGLNFVSDAQQYSKAGDVRYLKNKSS
                     NTLKNERQTIERPSFDNSLRFEDIEQPPKSTSTPVLSQSSQINVEREAPMFPVPYYIA
                     PSPMYNFSPYQNFVGNPTFLTPSHNPNLNYAIPIQRPELLYPNVNVYDSPLFKKTRLP
                     HQTKSLDKEKNYQYLPIYPVSISNNGDFVGQETPRAAPKLSKKRLSNTLDVNCSDYES
                     SGQNATYNDSESSLN"
     gene            complement(133026..133107)
                     /locus_tag="tS(AGA)H"
                     /db_xref="GeneID:856406"
     tRNA            complement(133026..133107)
                     /locus_tag="tS(AGA)H"
                     /product="tRNA-Ser"
                     /note="Serine tRNA (tRNA-Ser), predicted by tRNAscan-SE
                     analysis"
                     /db_xref="SGD:S000006726"
                     /db_xref="GeneID:856406"
     LTR             complement(133201..133442)
                     /note="Ty1 LTR"
                     /db_xref="SGD:S000006994"
     rep_origin      133438..133539
                     /note="ARS807;
                     Autonomously Replicating Sequence"
                     /db_xref="SGD:S000118357"
     LTR             complement(133565..133684)
                     /note="Ty1 LTR"
                     /db_xref="SGD:S000006995"
     LTR             133685..134009
                     /note="Ty1 LTR"
                     /db_xref="SGD:S000007007"
     gene            134321..134392
                     /locus_tag="tQ(UUG)H"
                     /db_xref="GeneID:856407"
     tRNA            134321..134392
                     /locus_tag="tQ(UUG)H"
                     /product="tRNA-Gln"
                     /note="Glutamine tRNA (tRNA-Gln), predicted by tRNAscan-SE
                     analysis; thiolation of uridine at wobble position (34)
                     requires Ncs6p"
                     /db_xref="SGD:S000006698"
                     /db_xref="GeneID:856407"
     gene            <134554..>136533
                     /gene="MIP6"
                     /locus_tag="YHR015W"
                     /db_xref="GeneID:856408"
     mRNA            <134554..>136533
                     /gene="MIP6"
                     /locus_tag="YHR015W"
                     /product="Mip6p"
                     /transcript_id="NM_001179145.1"
                     /db_xref="GI:296145388"
                     /db_xref="GeneID:856408"
     CDS             134554..136533
                     /gene="MIP6"
                     /locus_tag="YHR015W"
                     /note="Putative RNA-binding protein; interacts with
                     Mex67p, which is a component of the nuclear pore involved
                     in nuclear mRNA export; MIP6 has a paralog, PES4, that
                     arose from the whole genome duplication"
                     /codon_start=1
                     /product="Mip6p"
                     /protein_id="NP_011879.1"
                     /db_xref="GI:6321803"
                     /db_xref="SGD:S000001057"
                     /db_xref="GeneID:856408"
                     /translation="MPNSHGNVLNNISLNSKQNPRSISKSCPNDKDARQKSFKTISAQ
                     ALVRVQGAGYKLGDVKLKDAEVKEKNSLKKYDCKNATQEKKEQEQVFEKTVAKGSVQK
                     YITKTSKTNSLFIGNLKSTVTEEMLRKIFKRYQSFESAKVCRDFLTKKSLGYGYLNFK
                     DKNDAESARKEFNYTVFFGQEVKIMPSMKNTLFRKNIGTNVFFSNLPLENPQLTTRSF
                     YLIMIEYGNVLSCLLERRKNIGFVYFDNDISARNVIKKYNNQEFFGNKIICGLHFDKE
                     VRTRPEFTKRKKMIGSDIVIEDELLASNNLSDNARSKTILVKNLPSDTTQEEVLDYFS
                     TIGPIKSVFISEKQANTPHKAFVTYKNEEESKKAQKCLNKTIFKNHTIWVGPGKDKPV
                     HNQIGTNKKTKVYLKNLSFNCNKEFISQLCLQEKIRFSEIKITNYNSLNWTFCGHVEC
                     FSRSDAERLFNILDRRLIGSSLVEASWSKNNDNILNEIDYDDGNNNENYKKLINISSM
                     MRFRTQELSAHQKGLTSQFQQVVSPFSSYSNSYTNMNSLVATPMKPHPAFNLITNTVD
                     EKLHQPKRTKQENAEILESLKKIINRNLQRISISGLNKEENLRSISEFIFDVFWEHDS
                     ERLSHFLLMTNTSLESQKILQKQVTRAAESLGFTV"
     gene            complement(<136881..>138455)
                     /gene="YSC84"
                     /locus_tag="YHR016C"
                     /gene_synonym="LSB4"
                     /db_xref="GeneID:856409"
     mRNA            complement(join(<136881..138240,138409..>138455))
                     /gene="YSC84"
                     /locus_tag="YHR016C"
                     /gene_synonym="LSB4"
                     /product="Ysc84p"
                     /transcript_id="NM_001179146.1"
                     /db_xref="GI:296145389"
                     /db_xref="GeneID:856409"
     CDS             complement(join(136881..138240,138409..138455))
                     /gene="YSC84"
                     /locus_tag="YHR016C"
                     /gene_synonym="LSB4"
                     /note="Actin-binding protein; involved in bundling of
                     actin filaments and endocytosis of actin cortical patches;
                     activity stimulated by Las17p; contains SH3 domain similar
                     to Rvs167p; YSC84 has a paralog, LSB3, that arose from the
                     whole genome duplication"
                     /codon_start=1
                     /product="Ysc84p"
                     /protein_id="NP_011880.1"
                     /db_xref="GI:6321804"
                     /db_xref="SGD:S000001058"
                     /db_xref="GeneID:856409"
                     /translation="MGINNPIPRSLKSETKKAAKVLRSFVKPNQVFGADQVIPPYVLK
                     RAKGLAIITVLKAGFLFSGRAGSGVIVARLKDGTWSAPSAIAMAGAGAGGMVGVELTD
                     FVFILNSEEAVRSFSEFGTITLGGNVSVSAGPLGRSAEAAASASTGGVSAVFAYSKSK
                     GLFAGVSVEGSAILERREANRKFYGDNCTSKMILSGRVKVPPAADPLLRILESRAFNF
                     TRHDHDDNASGDDFYDDGQYSDNTSHYYDDIPDSFDSTDESSTRPNTRSSRRRGMSLG
                     SRSRYDDDYDDDGYGRGRGYGDFDSEDEDYDYGRSPNRNSSRNRGPQIDRGTKPRANT
                     RWEDDLYDRDTEYSRPNHSGRDYDNTRGNRRGYGRERGYSLGHGPTHPSNMSNVDDLS
                     HKMSKTGLGNESTATNSATPTAVALYNFAGEQPGDLAFKKGDVITILKKSDSQNDWWT
                     GRTNGKEGIFPANYVRVS"
     gene            <138694..>139851
                     /gene="YSC83"
                     /locus_tag="YHR017W"
                     /db_xref="GeneID:856410"
     mRNA            <138694..>139851
                     /gene="YSC83"
                     /locus_tag="YHR017W"
                     /product="Ysc83p"
                     /transcript_id="NM_001179147.1"
                     /db_xref="GI:296145390"
                     /db_xref="GeneID:856410"
     CDS             138694..139851
                     /gene="YSC83"
                     /locus_tag="YHR017W"
                     /note="Non-essential mitochondrial hypothetical protein;
                     mRNA induced during meiosis, peaking between mid to late
                     prophase of meiosis I; similar to S. douglasii YSD83"
                     /codon_start=1
                     /product="Ysc83p"
                     /protein_id="NP_011881.1"
                     /db_xref="GI:6321805"
                     /db_xref="SGD:S000001059"
                     /db_xref="GeneID:856410"
                     /translation="MAWSGGKDIVDQIFDAGYWLVSKSAVLSDEIKNHVEKSIESISG
                     KISNKETPRLQENDSNRSKVYKTLRIGLQDHWKLGLGISATSLCLYLGYRTFFKLPPN
                     LPEAESQVVLILGDMNDPIIRNQVMDLYRRRFTVYICTENADVYKKHEEDQDFIYYID
                     PTCEKDFEGFFVDVPRLASILFMPRLSYHPSGVISCDSLESEIHSSIFVYYQALLSII
                     PHLKRKTQLIMFNPSLTADLNLVHHSTEIITSGIIDSLFKIFKEYQRLNVSTIKLGIL
                     QIGSQPSNYKFLRMAGSDIHEALHYPVYKMIMSANGYKLRQLLSWLTTLGGYNSVYYC
                     GRFSYLVSWPFASLIFNHHTRLSLKRLRGRLAKVYSSIISFFCRSSSKSSK"
     gene            complement(<140011..>141402)
                     /gene="ARG4"
                     /locus_tag="YHR018C"
                     /db_xref="GeneID:856411"
     mRNA            complement(<140011..>141402)
                     /gene="ARG4"
                     /locus_tag="YHR018C"
                     /product="argininosuccinate lyase ARG4"
                     /transcript_id="NM_001179148.1"
                     /db_xref="GI:296145391"
                     /db_xref="GeneID:856411"
     CDS             complement(140011..141402)
                     /gene="ARG4"
                     /locus_tag="YHR018C"
                     /EC_number="4.3.2.1"
                     /note="Argininosuccinate lyase; catalyzes the final step
                     in the arginine biosynthesis pathway"
                     /codon_start=1
                     /product="argininosuccinate lyase ARG4"
                     /protein_id="NP_011882.1"
                     /db_xref="GI:6321806"
                     /db_xref="SGD:S000001060"
                     /db_xref="GeneID:856411"
                     /translation="MSDGTQKLWGGRFTGETDPLMHLYNASLPYDYKMYKADLEGTKV
                     YTAGLQKLGLLTETELAKIHEGLAEIKKEWDADKFVRHPNDEDIHTANERRLGELIGR
                     DIAGKVHTGRSRNDQVVTDLRIYCRDIVNDTLFPALKGLVEVLIKRAEGEIDVLMPGY
                     THLQRAQPIRWSHWLSSYATYFTEDYKRLGQILHRLNQSPLGAGALAGHPYGIDREFL
                     AEGLGFNSVIGNSLVAVSDRDFIVELMFWGTLFMNHISRFAEDLIIYCTAEFGFIQLS
                     DAYSTGSSLMPQKKNADSLELLRGKSGRVFGDLTGFLMSLKGIPSTYDKDMQEDKEPL
                     FDCLTTVEHSMLIATGVISTLTVNKEKMEAALTMDMLATDLADYLVRKGVPFRETHHI
                     SGECVATAERLGLSGIDKLTLEQYQKIDSRFGQDLFETFNFEQSVERRDATGGTAKSA
                     VLKQLDNLKSQLN"
     rep_origin      140349..141274
                     /note="ARS2;
                     Autonomously Replicating Sequence"
                     /db_xref="SGD:S000029042"
     gene            complement(<141894..>143558)
                     /gene="DED81"
                     /locus_tag="YHR019C"
                     /db_xref="GeneID:856412"
     mRNA            complement(<141894..>143558)
                     /gene="DED81"
                     /locus_tag="YHR019C"
                     /product="asparagine--tRNA ligase DED81"
                     /transcript_id="NM_001179149.1"
                     /db_xref="GI:296145392"
                     /db_xref="GeneID:856412"
     CDS             complement(141894..143558)
                     /gene="DED81"
                     /locus_tag="YHR019C"
                     /EC_number="6.1.1.22"
                     /note="Cytosolic asparaginyl-tRNA synthetase; required for
                     protein synthesis, catalyzes the specific attachment of
                     asparagine to its cognate tRNA"
                     /codon_start=1
                     /product="asparagine--tRNA ligase DED81"
                     /protein_id="NP_011883.1"
                     /db_xref="GI:6321807"
                     /db_xref="SGD:S000001061"
                     /db_xref="GeneID:856412"
                     /translation="MSSLYIKEATGVDELTTAGSQDHPFKTPAYALFASQQKSDATEP
                     KLFVFKTEDNEYQEISASALKKARKGCDGLKKKAVKQKEQELKKQQKEAENAAKQLSA
                     LNITIKEDESLPAAIKTRIYDSYSKVGQRVKVSGWIHRLRSNKKVIFVVLRDGSGFIQ
                     CVLSGDLALAQQTLDLTLESTVTLYGTIVKLPEGKTAPGGVELNVDYYEVVGLAPGGE
                     DSFTNKIAEGSDPSLLLDQRHLALRGDALSAVMKVRAALLKSVRRVYDEEHLTEVTPP
                     CMVQTQVEGGSTLFKMNYYGEEAYLTQSSQLYLETCLASLGDVYTIQESFRAEKSHTR
                     RHLSEYTHIEAELAFLTFDDLLQHIETLIVKSVQYVLEDPIAGPLVKQLNPNFKAPKA
                     PFMRLQYKDAITWLNEHDIKNEEGEDFKFGDDIAEAAERKMTDTIGVPIFLTRFPVEI
                     KSFYMKRCSDDPRVTESVDVLMPNVGEITGGSMRIDDMDELMAGFKREGIDTDAYYWF
                     IDQRKYGTCPHGGYGIGTERILAWLCDRFTVRDCSLYPRFSGRCKP"
     gene            <143996..>146062
                     /locus_tag="YHR020W"
                     /db_xref="GeneID:856413"
     mRNA            <143996..>146062
                     /locus_tag="YHR020W"
                     /product="proline--tRNA ligase"
                     /transcript_id="NM_001179150.1"
                     /db_xref="GI:296145393"
                     /db_xref="GeneID:856413"
     CDS             143996..146062
                     /locus_tag="YHR020W"
                     /EC_number="6.1.1.15"
                     /note="Prolyl-tRNA synthetase; N-terminal domain shows
                     weak homology to prokaryotic posttransfer editing domain,
                     but does not possess posttransfer editing activity; may
                     interact with ribosomes, based on co-purification
                     experiments"
                     /codon_start=1
                     /product="proline--tRNA ligase"
                     /protein_id="NP_011884.1"
                     /db_xref="GI:6321808"
                     /db_xref="SGD:S000001062"
                     /db_xref="GeneID:856413"
                     /translation="MPVSEAFAKLCVNEKPPAESAVAVKSLVFKPKTPKSATPVPIVV
                     VALQSTTTPSALIANATSSKDPRLARDDLVKQAFQSESARAFILGDLANATSNFHLLI
                     DHELGTVDGDTILQLNDSTYMKKSDMMKFLNNFEDSQKVVDFSQEVSKETATEGKKQQ
                     KKQQPSKAGTAAAAAAAALEDAKLIGITVDKALDFPGWYQQILTKGEMLDYYDVSGCY
                     ILRPPSYAIWENIQKWFDDKIKAIGVQNAYFPMFVSSRVLEKEKDHVEGFAPEVAWVT
                     RAGSSELEEPIAIRPTSETVMYPYYAKWVQSYRDLPLKLNQWNSVVRWEFKHPQPFLR
                     TREFLWQEGHTAHLTAKDAEEEVLQILDFYAGVYEELLAVPVVKGRKTEKEKFAGGDF
                     TTTCEGYIPQTGRGIQGATSHHLGQNFSKMFNLSVENPLGSDHPKIFAYQNSWGLSTR
                     VIGVMVMIHSDNKGLVIPPRVSQFQSVVIPVGITKKTSEEQRKHIHETARSVESRLKK
                     VGIRAFGDYNDNYTPGWKFSQYELKGIPIRIELGPKDIEKNQVVVVRRNDSKKYVVSF
                     DELEARIPEILEEMQGDLFKKAKELFDTHRVIVNEWSGFVPALNKKNVILAPWCGVME
                     CEEDIKESSAKKDDGEEFEEDDKAPSMGAKSLCIPFDQPVLNEGQKCIKCERIAVNYC
                     MFGRSY"
     gene            complement(146242..146314)
                     /locus_tag="tA(AGC)H"
                     /db_xref="GeneID:856414"
     tRNA            complement(146242..146314)
                     /locus_tag="tA(AGC)H"
                     /product="tRNA-Ala"
                     /note="Alanine tRNA (tRNA-Ala), predicted by tRNAscan-SE
                     analysis; one of 11 nuclear tRNA genes containing the
                     tDNA-anticodon AGC (converted to IGC in the mature tRNA),
                     decodes GCU and GCC codons into alanine, one of 16 nuclear
                     tRNAs for alanine"
                     /db_xref="SGD:S000006513"
                     /db_xref="GeneID:856414"
     LTR             complement(146331..146671)
                     /note="Ty3 LTR"
                     /db_xref="SGD:S000007003"
     LTR             146844..147114
                     /note="Ty4 LTR"
                     /db_xref="SGD:S000007010"
     gene            complement(<147871..>148669)
                     /gene="RPS27B"
                     /locus_tag="YHR021C"
                     /db_xref="GeneID:856415"
     mRNA            complement(join(<147871..148116,148667..>148669))
                     /gene="RPS27B"
                     /locus_tag="YHR021C"
                     /product="ribosomal 40S subunit protein S27B"
                     /transcript_id="NM_001179151.1"
                     /db_xref="GI:296145394"
                     /db_xref="GeneID:856415"
     CDS             complement(join(147871..148116,148667..148669))
                     /gene="RPS27B"
                     /locus_tag="YHR021C"
                     /note="Protein component of the small (40S) ribosomal
                     subunit; homologous to mammalian ribosomal protein S27, no
                     bacterial homolog; RPS27B has a paralog, RPS27A, that
                     arose from the whole genome duplication"
                     /codon_start=1
                     /product="ribosomal 40S subunit protein S27B"
                     /protein_id="NP_011885.1"
                     /db_xref="GI:6321809"
                     /db_xref="SGD:S000001063"
                     /db_xref="GeneID:856415"
                     /translation="MVLVQDLLHPTAASEARKHKLKTLVQGPRSYFLDVKCPGCLNIT
                     TVFSHAQTAVTCESCSTVLCTPTGGKAKLSEGTSFRRK"
     STS             148886..149709
                     /standard_name="D1S3690"
                     /db_xref="UniSTS:474268"
     gene            <149225..>149680
                     /gene="ECM12"
                     /locus_tag="YHR021W-A"
                     /db_xref="GeneID:856416"
     mRNA            <149225..>149680
                     /gene="ECM12"
                     /locus_tag="YHR021W-A"
                     /product="Ecm12p"
                     /transcript_id="NM_001181428.1"
                     /db_xref="GI:296145395"
                     /db_xref="GeneID:856416"
     CDS             149225..149680
                     /gene="ECM12"
                     /locus_tag="YHR021W-A"
                     /note="hypothetical protein; may contribute to cell wall
                     biosynthesis, mutants display zymolyase hypersensitivity"
                     /codon_start=1
                     /product="Ecm12p"
                     /protein_id="NP_011886.1"
                     /db_xref="GI:6321810"
                     /db_xref="SGD:S000003531"
                     /db_xref="GeneID:856416"
                     /translation="MNRSFHFLIKYIYIHVLLVFYFHIKQQAIMPFFIFFFSSFDGLS
                     FDLRVVAFLAKHVFVGVCSPFFVVGFFGSSRVVVTEWLSKLVLPPPPVSITQVFSLSR
                     KRGEFSSGYILIINPYKSFLRSLLDFSIFNNTAKNKSSTFTLNLEDVSK"
     gene            complement(<149575..>150345)
                     /locus_tag="YHR022C"
                     /db_xref="GeneID:856417"
     mRNA            complement(<149575..>150345)
                     /locus_tag="YHR022C"
                     /product="hypothetical protein"
                     /transcript_id="NM_001179152.1"
                     /db_xref="GI:296145396"
                     /db_xref="GeneID:856417"
     CDS             complement(149575..150345)
                     /locus_tag="YHR022C"
                     /note="hypothetical protein; YHR022C is not an essential
                     gene"
                     /codon_start=1
                     /product="hypothetical protein"
                     /protein_id="NP_011887.1"
                     /db_xref="GI:6321811"
                     /db_xref="SGD:S000001064"
                     /db_xref="GeneID:856417"
                     /translation="MSVRLSYGASLASIPRCFDLKSSKITVMGDDHSGKTSLVRSWLG
                     SSFQISDANRYRVSDLYHKTIQFDTLVKYYRTFGVKGQLPNYAGFKAKNSGTIYESCG
                     NFLEERLINANKSTAQRRTSIDVQVFDTNQMEVSYLSELTTLQIRQSDAIILCFDSTN
                     DSSLASLESYICIIHHVRLECELDIPIIIACTKCDLDSERTITHEKVLTFIQELGFSP
                     GNLDYFETSSKFNVNVEDLFLAVLLKIEKSKSDRRKLL"
     gene            complement(<151217..>151306)
                     /locus_tag="YHR022C-A"
                     /db_xref="GeneID:1466527"
     mRNA            complement(<151217..>151306)
                     /locus_tag="YHR022C-A"
                     /product="hypothetical protein"
                     /transcript_id="NM_001184597.1"
                     /db_xref="GI:296145397"
                     /db_xref="GeneID:1466527"
     CDS             complement(151217..151306)
                     /locus_tag="YHR022C-A"
                     /note="hypothetical protein; identified by gene-trapping,
                     microarray-based expression analysis, and genome-wide
                     homology searching"
                     /codon_start=1
                     /product="hypothetical protein"
                     /protein_id="NP_878087.1"
                     /db_xref="GI:33438805"
                     /db_xref="SGD:S000028645"
                     /db_xref="GeneID:1466527"
                     /translation="MKIKFSRGARFSATFSFDKYPFLLYEVVR"
     gene            <151666..>157452
                     /gene="MYO1"
                     /locus_tag="YHR023W"
                     /db_xref="GeneID:856418"
     mRNA            <151666..>157452
                     /gene="MYO1"
                     /locus_tag="YHR023W"
                     /product="myosin 1"
                     /transcript_id="NM_001179153.1"
                     /db_xref="GI:296145398"
                     /db_xref="GeneID:856418"
     CDS             151666..157452
                     /gene="MYO1"
                     /locus_tag="YHR023W"
                     /note="Type II myosin heavy chain; required for wild-type
                     cytokinesis and cell separation; localizes to the
                     actomyosin ring; binds to myosin light chains Mlc1p and
                     Mlc2p through its IQ1 and IQ2 motifs respectively"
                     /codon_start=1
                     /product="myosin 1"
                     /protein_id="NP_011888.1"
                     /db_xref="GI:6321812"
                     /db_xref="SGD:S000001065"
                     /db_xref="GeneID:856418"
                     /translation="MTGGQSCSSNMIVWIPDEKEVFVKGELMSTDINKNKFTGQEEQI
                     GIVHPLDSTEVSNLVQVRISDVFPVNPSTFDKVENMSELTHLNEPSVLYNLEKRYDCD
                     LIYTYSGLFLVAINPYHNLNLYSEDHINLYHNKHNRLSKSRLDENSHEKLPPHIFAIA
                     EEAYENLLSEGKDQSILVTGESGAGKTENTKKILQYLASITSGSPSNIAPVSGSSIVE
                     SFEMKILQSNPILESFGNAQTVRNNNSSRFGKFIKIEFNEHGMINGAHIEWYLLEKSR
                     IVHQNSKERNYHIFYQLLSGLDDSELKNLRLKSRNVKDYKILSNSNQDIIPGINDVEN
                     FKELLSALNIIGFSKDQIRWIFQVVAIILLIGNIEFVSDRAEQASFKNDVSAICSNLG
                     VDEKDFQTAILRPRSKAGKEWVSQSKNSQQAKFILNALSRNLYERLFGYIVDMINKNL
                     DHGSATLNYIGLLDIAGFEIFENNSFEQLCINYTNEKLQQFFNNHMFVLEQSEYLKEN
                     IQWDYIDYGKDLQLTIDLIESKGPPTGVLPLLDEEAVLPKSTDESFYSKLISTWDQNS
                     SKFKRSRLKNGFILKHYAGDVEYTVEGWLSKNKDPLNDNLLSLLSSSQNDIISKLFQP
                     EGEKSSSAGVEANISNQEVKKSARTSTFKTTSSRHREQQITLLNQLASTHPHFVRCII
                     PNNVKKVKTFNRRLILDQLRCNGVLEGIRLAREGYPNRIAFQEFFQRYRILYPENSTT
                     TTFSSKLKASTKQNCEFLLTSLQLDTKVYKIGNTKLFFKAGVLADLEKQKDVKLNNIM
                     IKLTATIRGYTVRKEITYHLQKLKKTRVIGNTFRLYNRLVKEDPWFNLFIRIKPLLTS
                     SNDMTRTKKFNEQINKLKNDLQEMESKKKFLEEKNQKTVNELENTQDLLNQEKENLRK
                     NESLLNRVKTSSETLQKQFDDLVSEKDEISREKLEVAQNLEEAHQKIQGLQETIRERE
                     ATLEKLHSKNNELIKQISDLNCDISKEQSSQSLIKESKLKLENEIKRLKDVINSKEEE
                     IKSFNDKLSSSEEDLDIKLVTLEKNCNIAMSRLQSLVTENSDLRSKNENFKKEKAALN
                     NQLKNKESELLKMKEKIDNHKKELATFSKQRDDAVSEHGKITAELKETRIQLTEYKSN
                     YQKIKEEYSNFQRETKEQEQKKRNSLVESLNDSKIKELEARLSQEISLNQYLNKRISG
                     NSVETNISSTRRSTSYSDDPLDKEDIIKKYYDLQLAFTEITRNLENEIEEKKNLISRL
                     RFTETRLASSSFEDQKIKAQMKKLKKLIQDMDPSIPLDSILNEPLDNCPDKESDINKL
                     MLEVDYLKRQLDIETRAHYDAENAISALHSKFRKIQGESSLSSSDIYKLKFEASEERV
                     KSLEDKLKTMPLRDRTNLPVGDIIKNRDSISKYEEEIRYYKLENYKLQEILNESNGKL
                     SQLTLDLRQSKSKEALLSEQLDRLQKDLESTERQKELLSSTIKQQKQQFENCMDDLQG
                     NELRLREHIHALKQAEEDVKNMASIIEKLKTQNKQKEKLIWEREMERNDSDMQLQETL
                     LELKRVQDVKKILSDDLAHLKERLSAVEDRSQYTDEINRLKEELNCSLKAETNLKKEF
                     ATLKYKLETSTNDSEAKISDLLKQLDHYTKVVEMLNNEKDAISLAEKELYQKYEALNT
                     ECESLKGKIVSLTKIKQELESDLNQKTDALQISNAALSSSTQKNKEITEKIKYLEETL
                     QLQMEQNSRNGELVKTLQASCNGYKDKFDDEKQKNIDLYEENQTLQKLNTDLQLQLKN
                     LHERLSDTTEKNAWLSKIHELENMVSLETDLKYEEMKKNKSLERAVEELQTKNSQQTD
                     VIELANKNRSEFEEATLKYEAQISDLEKYISQQELEMKKSIRDNSSYRDKVQEMAQEI
                     EFWKSRYESTMIGSKNIDSNNAQSKIFS"
     gene            complement(<157744..>159192)
                     /gene="MAS2"
                     /locus_tag="YHR024C"
                     /gene_synonym="MIF2"
                     /db_xref="GeneID:856419"
     mRNA            complement(<157744..>159192)
                     /gene="MAS2"
                     /locus_tag="YHR024C"
                     /gene_synonym="MIF2"
                     /product="Mas2p"
                     /transcript_id="NM_001179154.1"
                     /db_xref="GI:296145399"
                     /db_xref="GeneID:856419"
     CDS             complement(157744..159192)
                     /gene="MAS2"
                     /locus_tag="YHR024C"
                     /gene_synonym="MIF2"
                     /EC_number="3.4.24.64"
                     /note="Alpha subunit of the mitochondrial processing
                     protease (MPP); essential processing enzyme that cleaves
                     the N-terminal targeting sequences from mitochondrially
                     imported proteins"
                     /codon_start=1
                     /product="Mas2p"
                     /protein_id="NP_011889.1"
                     /db_xref="GI:6321813"
                     /db_xref="SGD:S000001066"
                     /db_xref="GeneID:856419"
                     /translation="MLRNGVQRLYSNIARTDNFKLSSLANGLKVATSNTPGHFSALGL
                     YIDAGSRFEGRNLKGCTHILDRLAFKSTEHVEGRAMAETLELLGGNYQCTSSRENLMY
                     QASVFNQDVGKMLQLMSETVRFPKITEQELQEQKLSAEYEIDEVWMKPELVLPELLHT
                     AAYSGETLGSPLICPRELIPSISKYYLLDYRNKFYTPENTVAAFVGVPHEKALELTEK
                     YLGDWQSTHPPITKKVAQYTGGESCIPPAPVFGNLPELFHIQIGFEGLPIDHPDIYAL
                     ATLQTLLGGGGSFSAGGPGKGMYSRLYTHVLNQYYFVENCVAFNHSYSDSGIFGISLS
                     CIPQAAPQAVEVIAQQMYNTFANKDLRLTEDEVSRAKNQLKSSLLMNLESKLVELEDM
                     GRQVLMHGRKIPVNEMISKIEDLKPDDISRVAEMIFTGNVNNAGNGKGRATVVMQGDR
                     GSFGDVENVLKAYGLGNSSSSKNDSPKKKGWF"
     gene            <159438..>160511
                     /gene="THR1"
                     /locus_tag="YHR025W"
                     /db_xref="GeneID:856420"
     mRNA            <159438..>160511
                     /gene="THR1"
                     /locus_tag="YHR025W"
                     /product="homoserine kinase"
                     /transcript_id="NM_001179155.1"
                     /db_xref="GI:296145400"
                     /db_xref="GeneID:856420"
     CDS             159438..160511
                     /gene="THR1"
                     /locus_tag="YHR025W"
                     /EC_number="2.7.1.39"
                     /note="Homoserine kinase; conserved protein required for
                     threonine biosynthesis; long-lived protein that is
                     preferentially retained in mother cells and forms
                     cytoplasmic filaments; expression is regulated by the
                     GCN4-mediated general amino acid control pathway"
                     /codon_start=1
                     /product="homoserine kinase"
                     /protein_id="NP_011890.1"
                     /db_xref="GI:6321814"
                     /db_xref="SGD:S000001067"
                     /db_xref="GeneID:856420"
                     /translation="MVRAFKIKVPASSANIGPGYDVLGVGLSLFLELDVTIDSSQAQE
                     TNDDPNNCKLSYTKESEGYSTVPLRSDANLITRTALYVLRCNNIRNFPSGTKVHVSNP
                     IPLGRGLGSSGAAVVAGVILGNEVAQLGFSKQRMLDYCLMIERHPDNITAAMMGGFCG
                     SFLRDLTPQEVERREIPLAEVLPEPSGGEDTGLVPPLPPTDIGRHVKYQWNPAIKCIA
                     IIPQFELSTADSRGVLPKAYPTQDLVFNLQRLAVLTTALTMDPPNADLIYPAMQDRVH
                     QPYRKTLIPGLTEILSCVTPSTYPGLLGICLSGAGPTILALATENFEEISQEIINRFA
                     KNGIKCSWKLLEPAYDGASVEQQ"
     gene            <160844..>161485
                     /gene="VMA16"
                     /locus_tag="YHR026W"
                     /gene_synonym="PPA1"
                     /db_xref="GeneID:856421"
     mRNA            <160844..>161485
                     /gene="VMA16"
                     /locus_tag="YHR026W"
                     /gene_synonym="PPA1"
                     /product="H(+)-transporting V0 sector ATPase subunit c''"
                     /transcript_id="NM_001179156.1"
                     /db_xref="GI:296145401"
                     /db_xref="GeneID:856421"
     CDS             160844..161485
                     /gene="VMA16"
                     /locus_tag="YHR026W"
                     /gene_synonym="PPA1"
                     /note="Subunit c'' of the vacuolar ATPase; v-ATPase
                     functions in acidification of the vacuole; one of three
                     proteolipid subunits of the V0 domain"
                     /codon_start=1
                     /product="H(+)-transporting V0 sector ATPase subunit c''"
                     /protein_id="NP_011891.1"
                     /db_xref="GI:6321815"
                     /db_xref="SGD:S000001068"
                     /db_xref="GeneID:856421"
                     /translation="MNKESKDDDMSLGKFSFSHFLYYLVLIVVIVYGLYKLFTGHGSD
                     INFGKFLLRTSPYMWANLGIALCVGLSVVGAAWGIFITGSSMIGAGVRAPRITTKNLI
                     SIIFCEVVAIYGLIIAIVFSSKLTVATAENMYSKSNLYTGYSLFWAGITVGASNLICG
                     IAVGITGATAAISDAADSALFVKILVIEIFGSILGLLGLIVGLLMAGKASEFQ"
     gene            complement(<161730..>164711)
                     /gene="RPN1"
                     /locus_tag="YHR027C"
                     /gene_synonym="HRD2; NAS1"
                     /db_xref="GeneID:856422"
     mRNA            complement(<161730..>164711)
                     /gene="RPN1"
                     /locus_tag="YHR027C"
                     /gene_synonym="HRD2; NAS1"
                     /product="proteasome regulatory particle base subunit
                     RPN1"
                     /transcript_id="NM_001179157.1"
                     /db_xref="GI:296145402"
                     /db_xref="GeneID:856422"
     CDS             complement(161730..164711)
                     /gene="RPN1"
                     /locus_tag="YHR027C"
                     /gene_synonym="HRD2; NAS1"
                     /note="Non-ATPase base subunit of the 19S RP of the 26S
                     proteasome; may participate in the recognition of several
                     ligands of the proteasome; contains a leucine-rich repeat
                     (LRR) domain, a site for protein-protein interactions; RP
                     is the acronym for regulatory particle"
                     /codon_start=1
                     /product="proteasome regulatory particle base subunit
                     RPN1"
                     /protein_id="NP_011892.1"
                     /db_xref="GI:6321816"
                     /db_xref="SGD:S000001069"
                     /db_xref="GeneID:856422"
                     /translation="MVDESDKKQQTIDEQSQISPEKQTPNKKDKKKEEEEQLSEEDAK
                     LKTDLELLVERLKEDDSSLYEASLNALKESIKNSTSSMTAVPKPLKFLRPTYPDLCSI
                     YDKWTDPNLKSSLADVLSILAMTYSENGKHDSLRYRLLSDVSDFEGWGHEYIRHLALE
                     IGEVYNDQVEKDAEDETSSDGSKSDGSAATSGFEFSKEDTLRLCLDIVPYFLKHNGEE
                     DAVDLLLEIESIDKLPQFVDENTFQRVCQYMVACVPLLPPPEDVAFLKTAYSIYLSQN
                     ELTDAIALAVRLGEEDMIRSVFDATSDPVMHKQLAYILAAQKTSFEYEGVQDIIGNGK
                     LSEHFLYLAKELNLTGPKVPEDIYKSHLDNSKSVFSSAGLDSAQQNLASSFVNGFLNL
                     GYCNDKLIVDNDNWVYKTKGDGMTSAVASIGSIYQWNLDGLQQLDKYLYVDEPEVKAG
                     ALLGIGISASGVHDGEVEPALLLLQDYVTNPDTKISSAAILGLGIAFAGSKNDEVLGL
                     LLPIAASTDLPIETAAMASLALAHVFVGTCNGDITTSIMDNFLERTAIELKTDWVRFL
                     ALALGILYMGQGEQVDDVLETISAIEHPMTSAIEVLVGSCAYTGTGDVLLIQDLLHRL
                     TPKNVKGEEDADEEETAEGQTNSISDFLGEQVNEPTKNEEAEIEVDEMEVDAEGEEVE
                     VKAEITEKKNGESLEGEEIKSEEKKGKSSDKDATTDGKNDDEEEEKEAGIVDELAYAV
                     LGIALIALGEDIGKEMSLRHFGHLMHYGNEHIRRMVPLAMGIVSVSDPQMKVFDTLTR
                     FSHDADLEVSMNSIFAMGLCGAGTNNARLAQLLRQLASYYSREQDALFITRLAQGLLH
                     LGKGTMTMDVFNDAHVLNKVTLASILTTAVGLVSPSFMLKHHQLFYMLNAGIRPKFIL
                     ALNDEGEPIKVNVRVGQAVETVGQAGRPKKITGWITQSTPVLLNHGERAELETDEYIS
                     YTSHIEGVVILKKNPDYREEE"
     gene            complement(<164978..>167434)
                     /gene="DAP2"
                     /locus_tag="YHR028C"
                     /gene_synonym="DPP2"
                     /db_xref="GeneID:856423"
     mRNA            complement(<164978..>167434)
                     /gene="DAP2"
                     /locus_tag="YHR028C"
                     /gene_synonym="DPP2"
                     /product="Dap2p"
                     /transcript_id="NM_001179158.1"
                     /db_xref="GI:296145403"
                     /db_xref="GeneID:856423"
     CDS             complement(164978..167434)
                     /gene="DAP2"
                     /locus_tag="YHR028C"
                     /gene_synonym="DPP2"
                     /EC_number="3.4.14.-"
                     /note="Dipeptidyl aminopeptidase; synthesized as a
                     glycosylated precursor; localizes to the vacuolar
                     membrane; similar to Ste13p"
                     /codon_start=1
                     /product="Dap2p"
                     /protein_id="NP_011893.1"
                     /db_xref="GI:6321817"
                     /db_xref="SGD:S000001070"
                     /db_xref="GeneID:856423"
                     /translation="MEGGEEEVERIPDELFDTKKKHLLDKLIRVGIILVLLIWGTVLL
                     LKSIPHHSNTPDYQEPNSNYTNDGKLKVSFSVVRNNTFQPKYHELQWISDNKIESNDL
                     GLYVTFMNDSYVVKSVYDDSYNSVLLEGKTFIHNGQNLTVESITASPDLKRLLIRTNS
                     VQNWRHSTFGSYFVYDKSSSSFEEIGNEVALAIWSPNSNDIAYVQDNNIYIYSAISKK
                     TIRAVTNDGSSFLFNGKPDWVYEEEVFEDDKAAWWSPTGDYLAFLKIDESEVGEFIIP
                     YYVQDEKDIYPEMRSIKYPKSGTPNPHAELWVYSMKDGTSFHPRISGNKKDGSLLITE
                     VTWVGNGNVLVKTTDRSSDILTVFLIDTIAKTSNVVRNESSNGGWWEITHNTLFIPAN
                     ETFDRPHNGYVDILPIGGYNHLAYFENSNSSHYKTLTEGKWEVVNGPLAFDSMENRLY
                     FISTRKSSTERHVYYIDLRSPNEIIEVTDTSEDGVYDVSFSSGRRFGLLTYKGPKVPY
                     QKIVDFHSRKAEKCDKGNVLGKSLYHLEKNEVLTKILEDYAVPRKSFRELNLGKDEFG
                     KDILVNSYEILPNDFDETLSDHYPVFFFAYGGPNSQQVVKTFSVGFNEVVASQLNAIV
                     VVVDGRGTGFKGQDFRSLVRDRLGDYEARDQISAASLYGSLTFVDPQKISLFGWSYGG
                     YLTLKTLEKDGGRHFKYGMSVAPVTDWRFYDSVYTERYMHTPQENFDGYVESSVHNVT
                     ALAQANRFLLMHGTGDDNVHFQNSLKFLDLLDLNGVENYDVHVFPDSDHSIRYHNANV
                     IVFDKLLDWAKRAFDGQFVK"
     gene            complement(<167677..>168561)
                     /gene="YHI9"
                     /locus_tag="YHR029C"
                     /db_xref="GeneID:856424"
     mRNA            complement(<167677..>168561)
                     /gene="YHI9"
                     /locus_tag="YHR029C"
                     /product="Yhi9p"
                     /transcript_id="NM_001179159.1"
                     /db_xref="GI:296145404"
                     /db_xref="GeneID:856424"
     CDS             complement(167677..168561)
                     /gene="YHI9"
                     /locus_tag="YHR029C"
                     /EC_number="5.1.-.-"
                     /note="hypothetical protein; null mutant is defective in
                     unfolded protein response; possibly involved in a membrane
                     regulation metabolic pathway; member of the PhzF
                     superfamily, though most likely not involved in phenazine
                     production"
                     /codon_start=1
                     /product="Yhi9p"
                     /protein_id="NP_011894.1"
                     /db_xref="GI:6321818"
                     /db_xref="SGD:S000001071"
                     /db_xref="GeneID:856424"
                     /translation="MTLMVPFKQVDVFTEKPFMGNPVAVINFLEIDENEVSQEELQAI
                     ANWTNLSETTFLFKPSDKKYDYKLRIFTPRSELPFAGHPTIGSCKAFLEFTKNTTATS
                     LVQECKIGAVPITINEGLISFKAPMADYESISSEMIADYEKAIGLKFIKPPALLHTGP
                     EWIVALVEDAETCFNANPNFAMLAHQTKQNDHVGIILAGPKKEAAIKNSYEMRAFAPV
                     INVYEDPVCGSGSVALARYLQEVYKFEKTTDITISEGGRLKRNGLMLASIKKEADNST
                     SYYIAGHATTVIDGKIKV"
     rep_origin      168549..168723
                     /note="ARS809;
                     Autonomously Replicating Sequence"
                     /db_xref="SGD:S000118358"
     gene            complement(<168890..>170344)
                     /gene="SLT2"
                     /locus_tag="YHR030C"
                     /gene_synonym="BYC2; LYT2; MPK1; SLK2"
                     /db_xref="GeneID:856425"
     mRNA            complement(<168890..>170344)
                     /gene="SLT2"
                     /locus_tag="YHR030C"
                     /gene_synonym="BYC2; LYT2; MPK1; SLK2"
                     /product="mitogen-activated serine/threonine-protein
                     kinase SLT2"
                     /transcript_id="NM_001179160.1"
                     /db_xref="GI:296145405"
                     /db_xref="GeneID:856425"
     CDS             complement(168890..170344)
                     /gene="SLT2"
                     /locus_tag="YHR030C"
                     /gene_synonym="BYC2; LYT2; MPK1; SLK2"
                     /EC_number="2.7.11.24"
                     /note="Serine/threonine MAP kinase; involved in regulating
                     maintenance of cell wall integrity, cell cycle
                     progression, and nuclear mRNA retention in heat shock;
                     required for mitophagy and pexophagy; affects recruitment
                     of mitochondria to phagophore assembly site (PAS); plays a
                     role in adaptive response of cells to cold; regulated by
                     the PKC1-mediated signaling pathway; SLT2 has a paralog,
                     KDX1, that arose from the whole genome duplication"
                     /codon_start=1
                     /product="mitogen-activated serine/threonine-protein
                     kinase SLT2"
                     /protein_id="NP_011895.1"
                     /db_xref="GI:6321819"
                     /db_xref="SGD:S000001072"
                     /db_xref="GeneID:856425"
                     /translation="MADKIERHTFKVFNQDFSVDKRFQLIKEIGHGAYGIVCSARFAE
                     AAEDTTVAIKKVTNVFSKTLLCKRSLRELKLLRHFRGHKNITCLYDMDIVFYPDGSIN
                     GLYLYEELMECDMHQIIKSGQPLTDAHYQSFTYQILCGLKYIHSADVLHRDLKPGNLL
                     VNADCQLKICDFGLARGYSENPVENSQFLTEYVATRWYRAPEIMLSYQGYTKAIDVWS
                     AGCILAEFLGGKPIFKGKDYVNQLNQILQVLGTPPDETLRRIGSKNVQDYIHQLGFIP
                     KVPFVNLYPNANSQALDLLEQMLAFDPQKRITVDEALEHPYLSIWHDPADEPVCSEKF
                     EFSFESVNDMEDLKQMVIQEVQDFRLFVRQPLLEEQRQLQLQQQQQQQQQQQQQQQQP
                     SDVDNGNAAASEENYPKQMATSNSVAPQQESFGIHSQNLPRHDADFPPRPQESMMEMR
                     PATGNTADIPPQNDNGTLLDLEKELEFGLDRKYF"
     gene            complement(<170799..>172970)
                     /gene="RRM3"
                     /locus_tag="YHR031C"
                     /gene_synonym="RTT104"
                     /db_xref="GeneID:856426"
     mRNA            complement(<170799..>172970)
                     /gene="RRM3"
                     /locus_tag="YHR031C"
                     /gene_synonym="RTT104"
                     /product="Rrm3p"
                     /transcript_id="NM_001179161.1"
                     /db_xref="GI:296145406"
                     /db_xref="GeneID:856426"
     CDS             complement(170799..172970)
                     /gene="RRM3"
                     /locus_tag="YHR031C"
                     /gene_synonym="RTT104"
                     /EC_number="3.6.4.-"
                     /EC_number="3.6.4.12"
                     /EC_number="3.6.1.-"
                     /note="DNA helicase involved in rDNA replication and Ty1
                     transposition; binds to and suppresses DNA damage at G4
                     motifs in vivo; relieves replication fork pauses at
                     telomeric regions; structurally and functionally related
                     to Pif1p"
                     /codon_start=1
                     /product="Rrm3p"
                     /protein_id="NP_011896.1"
                     /db_xref="GI:6321820"
                     /db_xref="SGD:S000001073"
                     /db_xref="GeneID:856426"
                     /translation="MFRSHASGNKKQWSKRSSNGSTPAASASGSHAYRQQTLSSFFMG
                     CGKKSAAASKNSTTIIDLESGDEGNRNITAPPRPRLIRNNSSSLFSQSQGSFGDDDPD
                     AEFKKLVDVPRLNSYKKSSRSLSMTSSLHKTASASTTQKTYHFDEDETLREVTSVKSN
                     SRQLSFTSTINIEDSSMKLSTDSERPAKRSKPSMEFQGLKLTVPKKIKPLLRKTVSNM
                     DSMNHRSASSPVVLTMEQERVVNLIVKKRTNVFYTGSAGTGKSVILQTIIRQLSSLYG
                     KESIAITASTGLAAVTIGGSTLHKWSGIGIGNKTIDQLVKKIQSQKDLLAAWRYTKVL
                     IIDEISMVDGNLLDKLEQIARRIRKNDDPFGGIQLVLTGDFFQLPPVAKKDEHNVVKF
                     CFESEMWKRCIQKTILLTKVFRQQDNKLIDILNAIRYGELTVDIAKTIRNLNRDIDYA
                     DGIAPTELYATRREVELSNVKKLQSLPGDLYEFKAVDNAPERYQAILDSSLMVEKVVA
                     LKEDAQVMMLKNKPDVELVNGSLGKVLFFVTESLVVKMKEIYKIVDDEVVMDMRLVSR
                     VIGNPLLKESKEFRQDLNARPLARLERLKILINYAVKISPHKEKFPYVRWTVGKNKYI
                     HELMVPERFPIDIPRENVGLERTQIPLMLCWALSIHKAQGQTIQRLKVDLRRIFEAGQ
                     VYVALSRAVTMDTLQVLNFDPGKIRTNERVKDFYKRLETLK"
     gene            <173344..>175089
                     /gene="ERC1"
                     /locus_tag="YHR032W"
                     /db_xref="GeneID:856427"
     mRNA            <173344..>175089
                     /gene="ERC1"
                     /locus_tag="YHR032W"
                     /product="Erc1p"
                     /transcript_id="NM_001179162.1"
                     /db_xref="GI:296145407"
                     /db_xref="GeneID:856427"
     CDS             173344..175089
                     /gene="ERC1"
                     /locus_tag="YHR032W"
                     /note="Member of the multi-drug and toxin extrusion (MATE)
                     family; the MATE family is part of the
                     multidrug/oligosaccharidyl-lipid/polysaccharide (MOP)
                     exporter superfamily; overproduction confers ethionine
                     resistance and accumulation of S-adenosylmethionine"
                     /codon_start=1
                     /product="Erc1p"
                     /protein_id="NP_011897.1"
                     /db_xref="GI:6321821"
                     /db_xref="SGD:S000001074"
                     /db_xref="GeneID:856427"
                     /translation="MSKQFSHTTNDRRSSIIYSTSVGKAGLFTPADYIPQESEENLIE
                     GEEQEGSEEEPSYTGNDDETEREGEYHSLLDANNSRTLQQEAWQQGYDSHDRKRLLDE
                     ERDLLIDNKLLSQHGNGGGDIESHGHGQAIGPDEEERPAEIANTWESAIESGQKISTT
                     FKRETQVITMNALPLIFTFILQNSLSLASIFSVSHLGTKELGGVTLGSMTANITGLAA
                     IQGLCTCLDTLCAQAYGAKNYHLVGVLVQRCAVITILAFLPMMYVWFVWSEKILALMI
                     PERELCALAANYLRVTAFGVPGFILFECGKRFLQCQGIFHASTIVLFVCAPLNALMNY
                     LLVWNDKIGIGYLGAPLSVVINYWLMTLGLLIYAMTTKHKERPLKCWNGIIPKEQAFK
                     NWRKMINLAIPGVVMVEAEFLGFEVLTIFASHLGTDALGAQSIVATIASLAYQVPFSI
                     SVSTSTRVANFIGASLYDSCMITCRVSLLLSFVCSSMNMFVICRYKEQIASLFSTESA
                     VVKMVVDTLPLLAFMQLFDAFNASTAGCLRGQGRQKNRWVHQPSRILLPRCAHGICVS
                     IPVSSGCRRLMVGYN"
     gene            <175548..>176819
                     /locus_tag="YHR033W"
                     /db_xref="GeneID:856428"
     mRNA            <175548..>176819
                     /locus_tag="YHR033W"
                     /product="putative glutamate 5-kinase"
                     /transcript_id="NM_001179163.1"
                     /db_xref="GI:296145408"
                     /db_xref="GeneID:856428"
     CDS             175548..176819
                     /locus_tag="YHR033W"
                     /note="hypothetical protein; epitope-tagged protein
                     localizes to the cytoplasm; YHR033W has a paralog, PRO1,
                     that arose from the whole genome duplication"
                     /codon_start=1
                     /product="putative glutamate 5-kinase"
                     /protein_id="NP_011898.1"
                     /db_xref="GI:6321822"
                     /db_xref="SGD:S000001075"
                     /db_xref="GeneID:856428"
                     /translation="MTKAYTIVIKLGSSSLVDESTKEPKLSIMTLIVETVTNLKRMGH
                     KVIIVSSGGIAVGLDALNIPHKPKQLSEVQAIAAVGQGRLIARWNMLFSQYGEQTAQI
                     LLTRNDILRWNQYNNARNTINELLAMGVIPIVNENDTLSISEIEFGDNDTLSAITAAL
                     VGADFLFLLTDVDCLYTDNPRTNPDARPIVLVPELSEGLPGVNTSSGSGSEVGTGGMR
                     TKLIAADLASNAGIETIVMKSDRPEYVPKIVDYIQHHFRPPRHIGNGTQQQFLDLQDT
                     ELEQLRRYDVPMHTKFLANDNKHKLKNREFWILHGLITKGAIIIDENSYDKLLSKDMA
                     SLTPNAVIEVRDNFHELECVDLKIGQRLPNGELDISKPIQSVGCVRSNYTSLELAKIK
                     GLPSEKIHDVLGYSVSEYVAHRENIAFPPQF"
     gene            complement(<176965..>177999)
                     /gene="PIH1"
                     /locus_tag="YHR034C"
                     /gene_synonym="NOP17"
                     /db_xref="GeneID:856429"
     mRNA            complement(<176965..>177999)
                     /gene="PIH1"
                     /locus_tag="YHR034C"
                     /gene_synonym="NOP17"
                     /product="Pih1p"
                     /transcript_id="NM_001179164.1"
                     /db_xref="GI:296145409"
                     /db_xref="GeneID:856429"
     CDS             complement(176965..177999)
                     /gene="PIH1"
                     /locus_tag="YHR034C"
                     /gene_synonym="NOP17"
                     /note="Component of the conserved R2TP complex
                     (Rvb1-Rvb2-Tah1-Pih1); R2TP complex interacts with Hsp90
                     (Hsp82p and Hsc82p) to mediate assembly large protein
                     complexes such as box C/D snoRNPs and RNA polymerase II"
                     /codon_start=1
                     /product="Pih1p"
                     /protein_id="NP_011899.1"
                     /db_xref="GI:6321823"
                     /db_xref="SGD:S000001076"
                     /db_xref="GeneID:856429"
                     /translation="MADFLLRPIKQRHRNEDKYVSVDAADGSVSKIEPIADFVIKTKL
                     LSANGPEKLQDGRKVFINVCHSPLVPKPEVDFNARIVFPLIIQNEWEIPIITSCYRMD
                     HDKKGQECYVWDCCINSDCSRWICDDIQLREILVEWCLESCEIRDSVVLCRDRIAFPK
                     MKKKGAELPALEVLNDELHQDYKAKMHKIIEEEAGDPMSILRGRNDDGDDNNDPDDGT
                     LPPLFPIENKISGAKIEEIDKNEIAHRNLKQAPAPAPAPHEQQEDVPEYEVKMKRFKG
                     AAYKLRILIENKAPNSKPDRFSPSYNFAENILYINGKLSIPLPRDIVVNAADIKIFHI
                     RKERTLYIYI"
     gene            <178219..>180111
                     /gene="NEL1"
                     /locus_tag="YHR035W"
                     /db_xref="GeneID:856430"
     mRNA            <178219..>180111
                     /gene="NEL1"
                     /locus_tag="YHR035W"
                     /product="Nel1p"
                     /transcript_id="NM_001179165.1"
                     /db_xref="GI:296145410"
                     /db_xref="GeneID:856430"
     CDS             178219..180111
                     /gene="NEL1"
                     /locus_tag="YHR035W"
                     /note="Activator of Sar1p GTPase activity; paralog of
                     Sec23 but does not associate with the COPII components;
                     not an essential gene"
                     /codon_start=1
                     /product="Nel1p"
                     /protein_id="NP_011900.1"
                     /db_xref="GI:6321824"
                     /db_xref="SGD:S000001077"
                     /db_xref="GeneID:856430"
                     /translation="MCSPTNFLYEPFSSDAVTQNYDQNLKCTKCGAYYSMACSLREQN
                     VWTCLFCNQSNSNAELPLVPSNTYTLTSAKKEILSRRTIMIIDAICDPHELNYLVSIL
                     CNNYITRQQEPLSIITIQQSGHVILHNAVNHRRDAVFSINEFMTKYNLDKLNASYFEK
                     KISEINQESYWFDKSTQGSLRKLLREICKIANKVNISSKRDKRCTGLALFVSSVLASQ
                     CSLSAYCHIVSFLNGPCTKGGGKVMSRERGESMRQNHHFESKSSQLQLSKSPTKFYKK
                     MLEKFANQSLIYEFFIASLDQIGILEMSPLITSSMAVSQFDSFNDERFAMSFQKYLNL
                     RDHNAIYNCHSKIMTAKNAIVVKDFPKYSLNPKNLSLPLEISLGHNSAEAPIQFQTTF
                     ENQTEKYIRIETLLLPKANRSFGAQNEIVFSMKKIASRIIDSFAYSSKHTKELMKQLF
                     LLPNQIRGKDVDMVNLIQWCYHIYRSPILSVRNTSPDERYLFLHRIINASKDTCLSLC
                     KPFIWSYSDLKHDWIVLDVPLTRAQILQDDKTTICVDGGSYLVLRRGKLLEKEGRELC
                     CKLLNDLQRFPQPLYVETKTGGSQDRFLKSKIIPLDITDKETLGTEDMTFNEYFNLFT
                     DLSGSK"
     gene            <180345..>181760
                     /gene="BRL1"
                     /locus_tag="YHR036W"
                     /db_xref="GeneID:856431"
     mRNA            <180345..>181760
                     /gene="BRL1"
                     /locus_tag="YHR036W"
                     /product="Brl1p"
                     /transcript_id="NM_001179166.1"
                     /db_xref="GI:296145411"
                     /db_xref="GeneID:856431"
     CDS             180345..181760
                     /gene="BRL1"
                     /locus_tag="YHR036W"
                     /note="Essential nuclear envelope integral membrane
                     protein; identified as a suppressor of a conditional
                     mutation in the major karyopherin, CRM1; homologous to and
                     interacts with Brr6p, a nuclear envelope protein involved
                     in nuclear export"
                     /codon_start=1
                     /product="Brl1p"
                     /protein_id="NP_011901.1"
                     /db_xref="GI:6321825"
                     /db_xref="SGD:S000001078"
                     /db_xref="GeneID:856431"
                     /translation="MESFENLSIRDSFTSGMEHVDEELGGLSDLSISKQGPTLSPQLI
                     NRFMPHFPSSPSPLRNTLDFSAAKADEEEDDRMEIDEVDDTSFEEEYNNEPIETHTEA
                     TENAVVEEIEATPEERQKQEKNESQDQSVEEVENIVSPHRSTVIKALLSPTDLGVAAA
                     TKVEGVVPLPPSANQDDNESSNNNAEGEDIIRNEEVEDEIKSSLGNHKSSQYANAFDS
                     EIIKRELRSRSKYQPIQVSFNTHNYFYSDKDGIKTYSLTKPNHNKIDEFYDQNEAFKL
                     PKPWSPNSHPASRASYALMSYLQLFLNAITTVVIFSFILSFIIALQKDLKSTWEQRKH
                     ELQYESRICQEQYLTNRCNQTPGLPALGEQCAIWKQCMDRNNDIFFRARSTLSAKLFG
                     DIINSFIDPLNWKTLFVIFCGVITWCFSSNFLLGFVRAKSYYGNGIKTYPLPSSPKSP
                     TSEETHSSMTASGEDSHLLKQ"
     gene            <181977..>183704
                     /gene="PUT2"
                     /locus_tag="YHR037W"
                     /db_xref="GeneID:856432"
     mRNA            <181977..>183704
                     /gene="PUT2"
                     /locus_tag="YHR037W"
                     /product="1-pyrroline-5-carboxylate dehydrogenase"
                     /transcript_id="NM_001179167.1"
                     /db_xref="GI:296145412"
                     /db_xref="GeneID:856432"
     CDS             181977..183704
                     /gene="PUT2"
                     /locus_tag="YHR037W"
                     /EC_number="1.2.1.88"
                     /note="Delta-1-pyrroline-5-carboxylate dehydrogenase;
                     nuclear-encoded mitochondrial protein involved in
                     utilization of proline as sole nitrogen source; deficiency
                     of the human homolog causes HPII, an autosomal recessive
                     inborn error of metabolism"
                     /codon_start=1
                     /product="1-pyrroline-5-carboxylate dehydrogenase"
                     /protein_id="NP_011902.1"
                     /db_xref="GI:6321826"
                     /db_xref="SGD:S000001079"
                     /db_xref="GeneID:856432"
                     /translation="MLSARCLKSIYFKRSFSQLGHIKPPKHIRNEPVKPFRNIDLKDW
                     DLLRASLMKFKSSSLEVPLVINGERIYDNNERALFPQTNPANHQQVLANVTQATEKDV
                     MNAVKAAKDAKKDWYNLPFYDRSAIFLKAADLISTKYRYDMLAATMLGQGKNVYQAEI
                     DCITELSDFFRYYVKYASDLYAQQPVESADGTWNKAEYRPLEGFVYAVSPFNFTAIAA
                     NLIGAPALMGNTVVWKPSQTAALSNYLLMTVLEEAGLPKGVINFIPGDPVQVTDQVLA
                     DKDFGALHFTGSTNVFKSLYGKIQSGVVEGKYRDYPRIIGETGGKNFHLVHPSANISH
                     AVLSTIRGTFEFQGQKCSAASRLYLPESKSEEFLSDMFGILQSQNVVPMNTSASPISG
                     GNLRGFMGPVIHEQSFDKLVKVIEDAKKDPELEILYGGQYDKSQGWFVGPTVIKAKRP
                     DHPYMSTEFFGPILTVYEYPDTEFNEICDIIDNTSQYALTGAIFAKDRKAIEYADEKL
                     KFSAGNFYINDKCTGAVVSQQWFGGARMSGTDDKAGGPNILSRFVSIRNTKENFYELT
                     DFKYPSNYE"
     gene            <184066..>184758
                     /gene="RRF1"
                     /locus_tag="YHR038W"
                     /gene_synonym="FIL1; KIM4"
                     /db_xref="GeneID:856433"
     mRNA            <184066..>184758
                     /gene="RRF1"
                     /locus_tag="YHR038W"
                     /gene_synonym="FIL1; KIM4"
                     /product="Rrf1p"
                     /transcript_id="NM_001179168.1"
                     /db_xref="GI:296145413"
                     /db_xref="GeneID:856433"
     CDS             184066..184758
                     /gene="RRF1"
                     /locus_tag="YHR038W"
                     /gene_synonym="FIL1; KIM4"
                     /note="Mitochondrial ribosome recycling factor; essential
                     for mitochondrial protein synthesis and for the
                     maintenance of the respiratory function of mitochondria"
                     /codon_start=1
                     /product="Rrf1p"
                     /protein_id="NP_011903.1"
                     /db_xref="GI:6321827"
                     /db_xref="SGD:S000001080"
                     /db_xref="GeneID:856433"
                     /translation="MILTTARLNCRPVTVPRLFNRSFSQSFIILKKKSSTPTEKVEED
                     EIDVNELLKKAETQFKKTLEIQKQKMNEIKQGNFNPKVFNSLVFKNNRKFTDIATTSL
                     KGKNALLITVFDPKDVKTVISGVLAANLNLTPERVPNNDLQLKVSLPPPTTESRLKVA
                     KDLKRVFEEYKQSSLKDSLGTIRGSILKEFKSFKKDDAVRKAERDLEKLHKDYVNKLH
                     DQFQKVEKSIVK"
     gene            complement(<184875..>186809)
                     /gene="MSC7"
                     /locus_tag="YHR039C"
                     /db_xref="GeneID:856434"
     mRNA            complement(<184875..>186809)
                     /gene="MSC7"
                     /locus_tag="YHR039C"
                     /product="Msc7p"
                     /transcript_id="NM_001179169.1"
                     /db_xref="GI:296145414"
                     /db_xref="GeneID:856434"
     CDS             complement(184875..186809)
                     /gene="MSC7"
                     /locus_tag="YHR039C"
                     /EC_number="1.2.1.-"
                     /note="hypothetical protein; green fluorescent protein
                     (GFP)-fusion protein localizes to the endoplasmic
                     reticulum; msc7 mutants are defective in directing meiotic
                     recombination events to homologous chromatids"
                     /codon_start=1
                     /product="Msc7p"
                     /protein_id="NP_011904.1"
                     /db_xref="GI:6321828"
                     /db_xref="SGD:S000001081"
                     /db_xref="GeneID:856434"
                     /translation="MSKVYLNSDMINHLNSTVQAYFNLWLEKQNAIMRSQPQIIQDNQ
                     KLIGITTLVASIFTLYVLVKIISTPAKCSSSYKPVKFSLPAPEAAQNNWKGKRSVSTN
                     IWNPEEPNFIQCHCPATGQYLGSFPSKTEADIDEMVSKAGKAQSTWGNSDFSRRLRVL
                     ASLHDYILNNQDLIARVACRDSGKTMLDASMGEILVTLEKIQWTIKHGQRALQPSRRP
                     GPTNFFMKWYKGAEIRYEPLGVISSIVSWNYPFHNLLGPIIAALFTGNAIVVKCSEQV
                     VWSSEFFVELIRKCLEACDEDPDLVQLCYCLPPTENDDSANYFTSHPGFKHITFIGSQ
                     PVAHYILKCAAKSLTPVVVELGGKDAFIVLDSAKNLDALSSIIMRGTFQSSGQNCIGI
                     ERVIVSKENYDDLVKILNDRMTANPLRQGSDIDHLENVDMGAMISDNRFDELEALVKD
                     AVAKGARLLQGGSRFKHPKYPQGHYFQPTLLVDVTPEMKIAQNEVFGPILVMMKAKNT
                     DHCVQLANSAPFGLGGSVFGADIKECNYVANSLQTGNVAINDFATFYVCQLPFGGING
                     SGYGKFGGEEGLLGLCNAKSVCFDTLPFVSTQIPKPLDYPIRNNAKAWNFVKSFIVGA
                     YTNSTWQRIKSLFSLAKEAS"
     gene            complement(<187173..>187679)
                     /gene="VMA10"
                     /locus_tag="YHR039C-A"
                     /gene_synonym="YHR039C-B"
                     /db_xref="GeneID:856435"
     mRNA            complement(join(<187173..187514,187677..>187679))
                     /gene="VMA10"
                     /locus_tag="YHR039C-A"
                     /gene_synonym="YHR039C-B"
                     /product="H(+)-transporting V1 sector ATPase subunit G"
                     /transcript_id="NM_001180027.1"
                     /db_xref="GI:296145415"
                     /db_xref="GeneID:856435"
     CDS             complement(join(187173..187514,187677..187679))
                     /gene="VMA10"
                     /locus_tag="YHR039C-A"
                     /gene_synonym="YHR039C-B"
                     /note="Subunit G of the V1 peripheral membrane domain of
                     V-ATPase; part of the electrogenic proton pump found
                     throughout the endomembrane system; involved in vacuolar
                     acidification; the V1 peripheral membrane domain of the
                     vacuolar H+-ATPase (V-ATPase) has eight subunits"
                     /codon_start=1
                     /product="H(+)-transporting V1 sector ATPase subunit G"
                     /protein_id="NP_011905.1"
                     /db_xref="GI:6321829"
                     /db_xref="SGD:S000002100"
                     /db_xref="GeneID:856435"
                     /translation="MSQKNGIATLLQAEKEAHEIVSKARKYRQDKLKQAKTDAAKEID
                     SYKIQKDKELKEFEQKNAGGVGELEKKAEAGVQGELAEIKKIAEKKKDDVVKILIETV
                     IKPSAEVHINAL"
     gene            <187924..>189024
                     /gene="BCD1"
                     /locus_tag="YHR040W"
                     /db_xref="GeneID:856436"
     mRNA            <187924..>189024
                     /gene="BCD1"
                     /locus_tag="YHR040W"
                     /product="Bcd1p"
                     /transcript_id="NM_001179170.1"
                     /db_xref="GI:296145416"
                     /db_xref="GeneID:856436"
     CDS             187924..189024
                     /gene="BCD1"
                     /locus_tag="YHR040W"
                     /note="Essential protein required for the accumulation of
                     box C/D snoRNA"
                     /codon_start=1
                     /product="Bcd1p"
                     /protein_id="NP_011906.1"
                     /db_xref="GI:6321830"
                     /db_xref="SGD:S000001082"
                     /db_xref="GeneID:856436"
                     /translation="MAVLCGVCGIKEFKYKCPRCLVQTCSLECSKKHKTRDNCSGQTH
                     DPKEYISSEALKQADDDKHERNAYVQRDYNYLTQLKRMVHVQKMDARMKNKRVLGPVG
                     GHNSNFKKRRYDIDEDDRDSTECQRIIRRGVNCLMLPKGMQRSSQNRSKWDKTMDLFV
                     WSVEWILCPMQEKGEKKELFKHVSHRIKETDFLVQGMGKNVFQKCCEFYRLAGTSSCI
                     EGEDGSETKEERTQILQKSGLKFYTKTFPYNTTHIMDSKKLVELAIHEKCIGELLKNT
                     TVIEFPTIFVAMTEADLPEGYEVLHQEPRPLEHTSTLNKFIDNAREEEDAEEDSQPTE
                     EPVQKETQDASDSDSDSDDDYNPGLSMDFLTA"
     gene            complement(<189131..>189864)
                     /gene="SRB2"
                     /locus_tag="YHR041C"
                     /gene_synonym="HRS2; MED20"
                     /db_xref="GeneID:856437"
     mRNA            complement(join(<189131..189749,189851..>189864))
                     /gene="SRB2"
                     /locus_tag="YHR041C"
                     /gene_synonym="HRS2; MED20"
                     /product="Srb2p"
                     /transcript_id="NM_001179171.1"
                     /db_xref="GI:296145417"
                     /db_xref="GeneID:856437"
     CDS             complement(join(189131..189749,189851..189864))
                     /gene="SRB2"
                     /locus_tag="YHR041C"
                     /gene_synonym="HRS2; MED20"
                     /note="Subunit of the RNA polymerase II mediator complex;
                     associates with core polymerase subunits to form the RNA
                     polymerase II holoenzyme; general transcription factor
                     involved in telomere maintenance"
                     /codon_start=1
                     /product="Srb2p"
                     /protein_id="NP_011907.1"
                     /db_xref="GI:6321831"
                     /db_xref="SGD:S000001083"
                     /db_xref="GeneID:856437"
                     /translation="MGKSAVIFVERATPATLTELKDALSNSILSVRDPWSIDFRTYRC
                     SIKNLPADVSKLMYSITFHHHGRQTVLIKDNSAMVTTAAAADIPPALVFNGSSTGVPE
                     SIDTILSSKLSNIWMQRQLIKGDAGETLILDGLTVRLVNLFSSTGFKGLLIELQADEA
                     GEFETKIAGIEGHLAEIRAKEYKTSSDSLGPDTSNEICDLAYQYVRALEL"
     gene            <190543..>192618
                     /gene="NCP1"
                     /locus_tag="YHR042W"
                     /gene_synonym="CPR1"
                     /db_xref="GeneID:856438"
     mRNA            <190543..>192618
                     /gene="NCP1"
                     /locus_tag="YHR042W"
                     /gene_synonym="CPR1"
                     /product="Ncp1p"
                     /transcript_id="NM_001179172.1"
                     /db_xref="GI:296145418"
                     /db_xref="GeneID:856438"
     CDS             190543..192618
                     /gene="NCP1"
                     /locus_tag="YHR042W"
                     /gene_synonym="CPR1"
                     /EC_number="1.6.2.4"
                     /note="NADP-cytochrome P450 reductase; involved in
                     ergosterol biosynthesis; associated and coordinately
                     regulated with Erg11p"
                     /codon_start=1
                     /product="Ncp1p"
                     /protein_id="NP_011908.1"
                     /db_xref="GI:6321832"
                     /db_xref="SGD:S000001084"
                     /db_xref="GeneID:856438"
                     /translation="MPFGIDNTDFTVLAGLVLAVLLYVKRNSIKELLMSDDGDITAVS
                     SGNRDIAQVVTENNKNYLVLYASQTGTAEDYAKKFSKELVAKFNLNVMCADVENYDFE
                     SLNDVPVIVSIFISTYGEGDFPDGAVNFEDFICNAEAGALSNLRYNMFGLGNSTYEFF
                     NGAAKKAEKHLSAAGAIRLGKLGEADDGAGTTDEDYMAWKDSILEVLKDELHLDEQEA
                     KFTSQFQYTVLNEITDSMSLGEPSAHYLPSHQLNRNADGIQLGPFDLSQPYIAPIVKS
                     RELFSSNDRNCIHSEFDLSGSNIKYSTGDHLAVWPSNPLEKVEQFLSIFNLDPETIFD
                     LKPLDPTVKVPFPTPTTIGAAIKHYLEITGPVSRQLFSSLIQFAPNADVKEKLTLLSK
                     DKDQFAVEITSKYFNIADALKYLSDGAKWDTVPMQFLVESVPQMTPRYYSISSSSLSE
                     KQTVHVTSIVENFPNPELPDAPPVVGVTTNLLRNIQLAQNNVNIAETNLPVHYDLNGP
                     RKLFANYKLPVHVRRSNFRLPSNPSTPVIMIGPGTGVAPFRGFIRERVAFLESQKKGG
                     NNVSLGKHILFYGSRNTDDFLYQDEWPEYAKKLDGSFEMVVAHSRLPNTKKVYVQDKL
                     KDYEDQVFEMINNGAFIYVCGDAKGMAKGVSTALVGILSRGKSITTDEATELIKMLKT
                     SGRYQEDVW"
     gene            complement(<192805..>193545)
                     /gene="DOG2"
                     /locus_tag="YHR043C"
                     /db_xref="GeneID:856439"
     mRNA            complement(<192805..>193545)
                     /gene="DOG2"
                     /locus_tag="YHR043C"
                     /product="Dog2p"
                     /transcript_id="NM_001179173.1"
                     /db_xref="GI:296145419"
                     /db_xref="GeneID:856439"
     CDS             complement(192805..193545)
                     /gene="DOG2"
                     /locus_tag="YHR043C"
                     /EC_number="3.1.3.68"
                     /note="2-deoxyglucose-6-phosphate phosphatase; member of a
                     family of low molecular weight phosphatases, induced by
                     oxidative and osmotic stress, confers 2-deoxyglucose
                     resistance when overexpressed; DOG2 has a paralog, DOG1,
                     that arose from a single-locus duplication; the last half
                     of DOG1 and DOG2 are subject to gene conversions among S.
                     cerevisiae, S. paradoxus, and S. mikatae"
                     /codon_start=1
                     /product="Dog2p"
                     /protein_id="NP_011909.1"
                     /db_xref="GI:6321833"
                     /db_xref="SGD:S000001085"
                     /db_xref="GeneID:856439"
                     /translation="MPQFSVDLCLFDLDGTIVSTTTAAESAWKKLCRQHGVDPVELFK
                     HSHGARSQEMMKKFFPKLDNTDNKGVLALEKDMADNYLDTVSLIPGAENLLLSLDVDT
                     ETQKKLPERKWAIVTSGSPYLAFSWFETILKNVGKPKVFITGFDVKNGKPDPEGYSRA
                     RDLLRQDLQLTGKQDLKYVVFEDAPVGIKAGKAMGAITVGITSSYDKSVLFDAGADYV
                     VCDLTQVSVVKNNENGIVIQVNNPLTRD"
     gene            complement(<194068..>194808)
                     /gene="DOG1"
                     /locus_tag="YHR044C"
                     /db_xref="GeneID:856440"
     mRNA            complement(<194068..>194808)
                     /gene="DOG1"
                     /locus_tag="YHR044C"
                     /product="Dog1p"
                     /transcript_id="NM_001179174.1"
                     /db_xref="GI:296145420"
                     /db_xref="GeneID:856440"
     CDS             complement(194068..194808)
                     /gene="DOG1"
                     /locus_tag="YHR044C"
                     /EC_number="3.1.3.68"
                     /note="2-deoxyglucose-6-phosphate phosphatase; member of a
                     family of low molecular weight phosphatases; confers
                     2-deoxyglucose resistance when overexpressed; DOG1 has a
                     paralog, DOG2, that arose from a single-locus duplication;
                     the last half of DOG1 and DOG2 are subject to gene
                     conversions among S. cerevisiae, S. paradoxus, and S.
                     mikatae"
                     /codon_start=1
                     /product="Dog1p"
                     /protein_id="NP_011910.1"
                     /db_xref="GI:6321834"
                     /db_xref="SGD:S000001086"
                     /db_xref="GeneID:856440"
                     /translation="MAEFSADLCLFDLDGTIVSTTVAAEKAWTKLCYEYGVDPSELFK
                     HSHGARTQEVLRRFFPKLDDTDNKGVLALEKDIAHSYLDTVSLIPGAENLLLSLDVDT
                     ETQKKLPERKWAIVTSGSPYLAFSWFETILKNVGKPKVFITGFDVKNGKPDPEGYSRA
                     RDLLRQDLQLTGKQDLKYVVFEDAPVGIKAGKAMGAITVGITSSYDKSVLFDAGADYV
                     VCDLTQVSVVKNNENGIVIQVNNPLTRA"
     gene            <195551..>197233
                     /locus_tag="YHR045W"
                     /db_xref="GeneID:856441"
     mRNA            <195551..>197233
                     /locus_tag="YHR045W"
                     /product="hypothetical protein"
                     /transcript_id="NM_001179175.1"
                     /db_xref="GI:296145421"
                     /db_xref="GeneID:856441"
     CDS             195551..197233
                     /locus_tag="YHR045W"
                     /note="hypothetical protein; possible role in iron
                     metabolism and/or amino acid and carbohydrate metabolism;
                     green fluorescent protein (GFP)-fusion protein localizes
                     to the endoplasmic reticulum"
                     /codon_start=1
                     /product="hypothetical protein"
                     /protein_id="NP_011911.1"
                     /db_xref="GI:6321835"
                     /db_xref="SGD:S000001087"
                     /db_xref="GeneID:856441"
                     /translation="MNWSFLLQLVITILLIVLGANWLLSSFLLDFKRDLTGVALSQQS
                     SISSVRKENETAYYRSILVPTGFPLTTGLGLSLKYKIRNGNFGDVWNAIMEVSKGKNI
                     IKFTGREKSYSLSELNGMAKRIFPKLSNKNFKNIGIANSIATVEGFTLSLASMMTSIR
                     TGSIPHFLPAVPRQRLEDVDVLIIDSWKSFKMLNGSEDWYKLIVVCDDPIESLQFDAN
                     CDVITWKELIDGFTKDTEYQYTPPDDNSDDKKLFAYVTSPWNGTNSFNQICLVSNIAE
                     FIKGFPLGNELNSNEYLTISTKLANSSASLQIWGKLFAVLLHGGSASFINPTTIDCES
                     LQETTLLFTETKDVVKLIDSNSRSGLLNKIYLSWATNLLSEGIFTKIARIEPHSLEKL
                     RCVYLADNVKDAEVISTFPEKIPQLKKTNRRITPSTEQLNKIRAQLGSRVVLELYCPY
                     AIMGPVAHTNFYDYRVFGKSVDDNVVCYGTLSTTLEGKMVETETNPHLNIEKKQGMLC
                     IRGFSIGKPVESDRLEKALHLAERFGGGEGWMPLVGVFGLFGQDGCLYIYNQ"
     gene            complement(<197398..>198285)
                     /gene="INM1"
                     /locus_tag="YHR046C"
                     /db_xref="GeneID:856442"
     mRNA            complement(<197398..>198285)
                     /gene="INM1"
                     /locus_tag="YHR046C"
                     /product="inositol monophosphate 1-phosphatase INM1"
                     /transcript_id="NM_001179176.1"
                     /db_xref="GI:296145422"
                     /db_xref="GeneID:856442"
     CDS             complement(197398..198285)
                     /gene="INM1"
                     /locus_tag="YHR046C"
                     /EC_number="3.1.3.25"
                     /note="Inositol monophosphatase; involved in biosynthesis
                     of inositol and in phosphoinositide second messenger
                     signaling; INM1 expression increases in the presence of
                     inositol and decreases upon exposure to antibipolar drugs
                     lithium and valproate"
                     /codon_start=1
                     /product="inositol monophosphate 1-phosphatase INM1"
                     /protein_id="NP_011912.1"
                     /db_xref="GI:6321836"
                     /db_xref="SGD:S000001088"
                     /db_xref="GeneID:856442"
                     /translation="MTIDLASIEKFLCELATEKVGPIIKSKSGTQKDYDLKTGSRSVD
                     IVTAIDKQVEKLIWESVKTQYPTFKFIGEESYVKGETVITDDPTFIIDPIDGTTNFVH
                     DFPFSCTSLGLTVNKEPVVGVIYNPHINLLVSASKGNGMRVNNKDYDYKSKLESMGSL
                     ILNKSVVALQPGSAREGKNFQTKMATYEKLLSCDYGFVHGFRNLGSSAMTMAYIAMGY
                     LDSYWDGGCYSWDVCAGWCILKEVGGRVVGANPGEWSIDVDNRTYLAVRGTINNESDE
                     QTKYITDFWNCVDGHLKYD"
     gene            complement(<198740..>201310)
                     /gene="AAP1"
                     /locus_tag="YHR047C"
                     /gene_synonym="AAP1'"
                     /db_xref="GeneID:856443"
     mRNA            complement(<198740..>201310)
                     /gene="AAP1"
                     /locus_tag="YHR047C"
                     /gene_synonym="AAP1'"
                     /product="Aap1p"
                     /transcript_id="NM_001179177.1"
                     /db_xref="GI:296145423"
                     /db_xref="GeneID:856443"
     CDS             complement(198740..201310)
                     /gene="AAP1"
                     /locus_tag="YHR047C"
                     /gene_synonym="AAP1'"
                     /EC_number="3.4.11.-"
                     /note="Arginine/alanine amino peptidase; overproduction
                     stimulates glycogen accumulation; AAP1 has a paralog,
                     APE2, that arose from the whole genome duplication"
                     /codon_start=1
                     /product="Aap1p"
                     /protein_id="NP_011913.1"
                     /db_xref="GI:6321837"
                     /db_xref="SGD:S000001089"
                     /db_xref="GeneID:856443"
                     /translation="MSREVLPNNVTPLHYDITLEPNFRAFTFEGSLKIDLQINDHSIN
                     SVQINYLEIDFHSARIEGVNAIEVNKNENQQKATLVFPNGTFENLGPSAKLEIIFSGI
                     LNDQMAGFYRAKYTDKVTGETKYMATTQMEATDARRAFPCFDEPNLKATFAVTLVSES
                     FLTHLSNMDVRNETIKEGKKYTTFNTTPKMSTYLVAFIVADLRYVESNNFRIPVRVYS
                     TPGDEKFGQFAANLAARTLRFFEDTFNIEYPLPKMDMVAVHEFSAGAMENWGLVTYRV
                     IDLLLDIENSSLDRIQRVAEVIQHELAHQWFGNLVTMDWWEGLWLNEGFATWMSWYSC
                     NKFQPEWKVWEQYVTDNLQRALNLDSLRSSHPIEVPVNNADEINQIFDAISYSKGSSL
                     LRMISKWLGEETFIKGVSQYLNKFKYGNAKTGDLWDALADASGKDVCSVMNIWTKRVG
                     FPVLSVKEHKNKITLTQHRYLSTGDVKEEEDTTIYPILLALKDSTGIDNTLVLNEKSA
                     TFELKNEEFFKINGDQSGIFITSYSDERWAKLSKQANLLSVEDRVGLVADAKALSASG
                     YTSTTNFLNLISNWKNEDSFVVWEQIINSLSALKSTWVFEPEDILNALDKFTLDLVLN
                     KLSELGWNIGEDDSFAIQRLKVTLFSAACTSGNEKMQSIAVEMFEEYANGNKQAIPAL
                     FKAVVFNTVARLGGENNYEKIFNIYQNPVSSEEKIIALRALGRFEDKELLERTLSYLL
                     DGTVLNQDFYIPMQGIRVHKKGIERLWAWMQEHWDEIAKRLQPGSPVLGGVLTLGLTN
                     FTSFEALEKISAFYSRKVTKGFDQTLAQALDTIRSKAQWVSRDREIVATYLREHEYDQ
                     "
     gene            <204607..>206151
                     /gene="YHK8"
                     /locus_tag="YHR048W"
                     /db_xref="GeneID:856444"
     mRNA            <204607..>206151
                     /gene="YHK8"
                     /locus_tag="YHR048W"
                     /product="Yhk8p"
                     /transcript_id="NM_001179178.1"
                     /db_xref="GI:296145424"
                     /db_xref="GeneID:856444"
     CDS             204607..206151
                     /gene="YHK8"
                     /locus_tag="YHR048W"
                     /note="Presumed antiporter of the major facilitator
                     superfamily; member of the 12-spanner drug:H(+) antiporter
                     DHA1 family; expression of gene is up-regulated in cells
                     exhibiting reduced susceptibility to azoles"
                     /codon_start=1
                     /product="Yhk8p"
                     /protein_id="NP_011914.1"
                     /db_xref="GI:6321838"
                     /db_xref="SGD:S000001090"
                     /db_xref="GeneID:856444"
                     /translation="MVAEFQIASAQSSALTSTEEEHCSINSDKAAKLDLELTSERKND
                     GKQSHEVTFNEDIADPEDIARHMSTARRYYISSLITFTSMVITMISSSWTLPSTHIIE
                     HFHISHEVSTLGITLYVFGLGIGPLFLSPLSELYGRRITFLYALTLSIIWQCLTIWSK
                     TITGVMFGRFLSGFFGSAFLSVAGGAIADIFDKDQIGIPMAIYTTSAFLGPSLGPIIG
                     GALYHQSYKWTFITLLITSGCCLVMIIFTIPETYKPMLLIRKAKRLRKEKNDQRYYAV
                     LEVTREQTSLLSAIFLSTKRPFGLLLRDRMMGVLCFYTGLELAIIYLYFVAFPYVFKK
                     LYNFGPMEIACSYIGIMVGMILSAPTCLLFQKTFEWRVKRNNGVKTPEMRFEPLFYGA
                     FLTPVGLFIFAFTCYKHVHWIAPIIGSAIFGSGVYFVFTGVFAYTVDAYRRYAASGMA
                     CNTFVRCIMAGVFPLFGLQMYKSMGVNWAGFLLAMVTVAMIPVPFLFTKYGARLRAKS
                     PYAWDD"
     gene            <206462..>207193
                     /gene="FSH1"
                     /locus_tag="YHR049W"
                     /db_xref="GeneID:856445"
     mRNA            <206462..>207193
                     /gene="FSH1"
                     /locus_tag="YHR049W"
                     /product="Fsh1p"
                     /transcript_id="NM_001179179.1"
                     /db_xref="GI:296145425"
                     /db_xref="GeneID:856445"
     CDS             206462..207193
                     /gene="FSH1"
                     /locus_tag="YHR049W"
                     /EC_number="3.1.-.-"
                     /note="Putative serine hydrolase; localizes to both the
                     nucleus and cytoplasm; sequence is similar to S.
                     cerevisiae Fsh2p and Fsh3p and the human candidate tumor
                     suppressor OVCA2"
                     /codon_start=1
                     /product="Fsh1p"
                     /protein_id="NP_011915.1"
                     /db_xref="GI:6321839"
                     /db_xref="SGD:S000001091"
                     /db_xref="GeneID:856445"
                     /translation="MTVQIPKLLFLHGFLQNGKVFSEKSSGIRKLLKKANVQCDYIDA
                     PVLLEKKDLPFEMDDEKWQATLDADVNRAWFYHSEISHELDISEGLKSVVDHIKANGP
                     YDGIVGFSQGAALSSIITNKISELVPDHPQFKVSVVISGYSFTEPDPEHPGELRITEK
                     FRDSFAVKPDMKTKMIFIYGASDQAVPSVRSKYLYDIYLKAQNGNKEKVLAYEHPGGH
                     MVPNKKDIIRPIVEQITSSLQEASE"
     gene            <207654..>209303
                     /gene="SMF2"
                     /locus_tag="YHR050W"
                     /db_xref="GeneID:856447"
     mRNA            <207654..>209303
                     /gene="SMF2"
                     /locus_tag="YHR050W"
                     /product="divalent metal ion transporter SMF2"
                     /transcript_id="NM_001179180.1"
                     /db_xref="GI:296145426"
                     /db_xref="GeneID:856447"
     CDS             207654..209303
                     /gene="SMF2"
                     /locus_tag="YHR050W"
                     /note="Divalent metal ion transporter involved in
                     manganese homeostasis; has broad specificity for di-valent
                     and tri-valent metals; post-translationally regulated by
                     levels of metal ions; member of the Nramp family of metal
                     transport proteins"
                     /codon_start=1
                     /product="divalent metal ion transporter SMF2"
                     /protein_id="NP_011917.1"
                     /db_xref="GI:6321841"
                     /db_xref="SGD:S000001092"
                     /db_xref="GeneID:856447"
                     /translation="MTSQEYEPIQWSDESQTNNDSVNDAYADVNTTHESRRRTTLQPN
                     STSQSMIGTLRKYARFIGPGLMVSVSYMDPGNYSTAVAAGSAHRYKLLFSVLVSNFMA
                     AFWQYLCARLGAVTGLDLAQNCKKHLPFGLNITLYILAEMAIIATDLAEVVGTAISLN
                     ILFHIPLALGVILTVVDVLIVLLAYKPNGSMKGIRIFEAFVSLLVVLTVVCFTVELFY
                     AKLGPAKEIFSGFLPSKAVFEGDGLYLSLAILGATVMPHSLYLGSGVVQPRLREYDIK
                     NGHYLPDANDMDNNHDNYRPSYEAISETLHFTITELLISLFTVALFVNCAILIVSGAT
                     LYGSTQNAEEADLFSIYNLLCSTLSKGAGTVFVLALLFSGQSAGIVCTLSGQMVSEGF
                     LNWTVSPALRRSATRAVAITPCLILVLVAGRSGLSGALNASQVVLSLLLPFVSAPLLY
                     FTSSKKIMRVQLNRTKELSRTTDKKPVADRTEDDETIELEEMGIGSSSQERSLVSPAP
                     EYKDMSNGMIVTVLAIIVWLIISGLNFYMLLGFTTGKEVHL"
     gene            <209475..>209645
                     /locus_tag="YHR050W-A"
                     /db_xref="GeneID:1466528"
     mRNA            <209475..>209645
                     /locus_tag="YHR050W-A"
                     /product="hypothetical protein"
                     /transcript_id="NM_001184652.1"
                     /db_xref="GI:296145427"
                     /db_xref="GeneID:1466528"
     CDS             209475..209645
                     /locus_tag="YHR050W-A"
                     /note="hypothetical protein; identified by expression
                     profiling and mass spectrometry"
                     /codon_start=1
                     /product="hypothetical protein"
                     /protein_id="NP_878088.1"
                     /db_xref="GI:33438806"
                     /db_xref="SGD:S000028832"
                     /db_xref="GeneID:1466528"
                     /translation="MKRDLIGPVKALIKINNCSCLSRCQISRLPHFFTFHPHFSTLIY
                     YYNLKNCITSET"
     gene            <209705..>210151
                     /gene="COX6"
                     /locus_tag="YHR051W"
                     /db_xref="GeneID:856448"
     mRNA            <209705..>210151
                     /gene="COX6"
                     /locus_tag="YHR051W"
                     /product="cytochrome c oxidase subunit VI"
                     /transcript_id="NM_001179181.1"
                     /db_xref="GI:296145428"
                     /db_xref="GeneID:856448"
     CDS             209705..210151
                     /gene="COX6"
                     /locus_tag="YHR051W"
                     /EC_number="1.9.3.1"
                     /note="Subunit VI of cytochrome c oxidase (Complex IV);
                     Complex IV is the terminal member of the mitochondrial
                     inner membrane electron transport chain; expression is
                     regulated by oxygen levels"
                     /codon_start=1
                     /product="cytochrome c oxidase subunit VI"
                     /protein_id="NP_011918.1"
                     /db_xref="GI:6321842"
                     /db_xref="SGD:S000001093"
                     /db_xref="GeneID:856448"
                     /translation="MLSRAIFRNPVINRTLLRARPGAYHATRLTKNTFIQSRKYSDAH
                     DEETFEEFTARYEKEFDEAYDLFEVQRVLNNCFSYDLVPAPAVIEKALRAARRVNDLP
                     TAIRVFEALKYKVENEDQYKAYLDELKDVRQELGVPLKEELFPSSS"
     gene            <210848..>211978
                     /gene="CIC1"
                     /locus_tag="YHR052W"
                     /gene_synonym="NSA3"
                     /db_xref="GeneID:856449"
     mRNA            <210848..>211978
                     /gene="CIC1"
                     /locus_tag="YHR052W"
                     /gene_synonym="NSA3"
                     /product="Cic1p"
                     /transcript_id="NM_001179182.1"
                     /db_xref="GI:296145429"
                     /db_xref="GeneID:856449"
     CDS             210848..211978
                     /gene="CIC1"
                     /locus_tag="YHR052W"
                     /gene_synonym="NSA3"
                     /note="Essential protein that interacts with proteasome
                     components; has a potential role in proteasome substrate
                     specificity; also copurifies with 66S pre-ribosomal
                     particles"
                     /codon_start=1
                     /product="Cic1p"
                     /protein_id="NP_011919.1"
                     /db_xref="GI:6321843"
                     /db_xref="SGD:S000001094"
                     /db_xref="GeneID:856449"
                     /translation="MAKKSNSKKSTPVSTPSKEKKKVIEKKSSTAIPRERVIKAVNEL
                     IKFTSKPQDENNEEGNNGKKNLLEDDEEELKKDLQLIVVNNKSFTGTSKSFKLKLLNV
                     KHSFYKPWKEASATAVKDFKVLLILKDSDIKKVSEDDLFDQLDSEGIKVDEIICGKDL
                     KTVYKAYEARNAFISQFSLILADDSIVTSLPKLMGGKAYNKVETTPISIRTHANKEFS
                     LTTLTNNIKKVYMNQLPVKLPRGTTLNVHLGNLEWLRPEEFVDNVELISEQLIKAYQI
                     RSIFIKTNRSPVLPLYYNQDVLDELEAKKDKIEETHEDDMVTIDGVQVHLSTFNKGLM
                     EIANPSELGSIFSKQINNAKKRSSSELEKESSESEAVKKAKS"
     gene            212409..213118
                     /locus_tag="RUF5-1"
                     /db_xref="GeneID:9164903"
     ncRNA           212409..213118
                     /ncRNA_class="other"
                     /locus_tag="RUF5-1"
                     /product="RUF5-1"
                     /note="ncRNA; RNA of Unknown Function"
                     /transcript_id="NR_132186.1"
                     /db_xref="GI:831416111"
                     /db_xref="SGD:S000028470"
                     /db_xref="GeneID:9164903"
     gene            complement(<212535..>212720)
                     /gene="CUP1-1"
                     /locus_tag="YHR053C"
                     /gene_synonym="CUP1"
                     /db_xref="GeneID:856450"
     mRNA            complement(<212535..>212720)
                     /gene="CUP1-1"
                     /locus_tag="YHR053C"
                     /gene_synonym="CUP1"
                     /product="metallothionein CUP1"
                     /transcript_id="NM_001179185.1"
                     /db_xref="GI:296145432"
                     /db_xref="GeneID:856450"
     CDS             complement(212535..212720)
                     /gene="CUP1-1"
                     /locus_tag="YHR053C"
                     /gene_synonym="CUP1"
                     /note="Metallothionein; binds copper and mediates
                     resistance to high concentrations of copper and cadmium;
                     locus is variably amplified in different strains, with two
                     copies, CUP1-1 and CUP1-2, in the genomic sequence
                     reference strain S288C; CUP1-1 has a paralog, CUP1-2, that
                     arose from a segmental duplication"
                     /codon_start=1
                     /product="metallothionein CUP1"
                     /protein_id="NP_011922.1"
                     /db_xref="GI:6321846"
                     /db_xref="SGD:S000001095"
                     /db_xref="GeneID:856450"
                     /translation="MFSELINFQNEGHECQCQCGSCKNNEQCQKSCSCPTGCNSDDKC
                     PCGNKSEETKKSCCSGK"
     rep_origin      212720..213185
                     /note="ARS810;
                     Putative replication origin; identified in multiple array
                     studies, not yet confirmed by plasmid-based assay"
                     /db_xref="SGD:S000130147"
     gene            complement(<213185..>214249)
                     /locus_tag="YHR054C"
                     /db_xref="GeneID:856451"
     mRNA            complement(<213185..>214249)
                     /locus_tag="YHR054C"
                     /product="hypothetical protein"
                     /transcript_id="NM_001179184.1"
                     /db_xref="GI:296145431"
                     /db_xref="GeneID:856451"
     CDS             complement(213185..214249)
                     /locus_tag="YHR054C"
                     /note="hypothetical protein; partial duplicate of
                     RSC30/YHR056C, truncated remnant of segmental duplication"
                     /codon_start=1
                     /product="hypothetical protein"
                     /protein_id="NP_011921.1"
                     /db_xref="GI:6321845"
                     /db_xref="SGD:S000001096"
                     /db_xref="GeneID:856451"
                     /translation="MVPAAENLSPIPASIDTNDIPLIANDLKLLETQAKLINILQGVP
                     FYLPVNLTKIESLLETLTMGVSNTVDLYFHDNEVRKEWKDTLNFINTIVYTNFFLFVQ
                     NESSLSMAVQHSSNNNKTSNSERCAKDLMKIISNMHIFYSITFNFIFPIKSIKSFSSG
                     NNRFHSNGKEFLFANHFIEILQNFIAITFAIFQRCEVILYDEFYKNLSNEEINVQLLL
                     IHDKILEILKKIEIIVSFLRDEMNSNGSFKSIKGFNKVLNLIKYMLRFSKKKQNFARN
                     SDNNNVTDYSQSAKNKNVLLKFPVSELNRIYLKFKEISDFLMEREVVQRSIIIDKDLE
                     SDNLGITTANFNDFYDAFYN"
     gene            214407..215116
                     /locus_tag="RUF5-2"
                     /db_xref="GeneID:9164904"
     ncRNA           214407..215116
                     /ncRNA_class="other"
                     /locus_tag="RUF5-2"
                     /product="RUF5-2"
                     /note="ncRNA; RNA of Unknown Function"
                     /transcript_id="NR_132187.1"
                     /db_xref="GI:831416112"
                     /db_xref="SGD:S000028474"
                     /db_xref="GeneID:9164904"
     gene            complement(<214533..>214718)
                     /gene="CUP1-2"
                     /locus_tag="YHR055C"
                     /gene_synonym="CUP1"
                     /db_xref="GeneID:856452"
     mRNA            complement(<214533..>214718)
                     /gene="CUP1-2"
                     /locus_tag="YHR055C"
                     /gene_synonym="CUP1"
                     /product="metallothionein CUP1"
                     /transcript_id="NM_001179183.1"
                     /db_xref="GI:296145430"
                     /db_xref="GeneID:856452"
     CDS             complement(214533..214718)
                     /gene="CUP1-2"
                     /locus_tag="YHR055C"
                     /gene_synonym="CUP1"
                     /note="Metallothionein; binds copper and mediates
                     resistance to high concentrations of copper and cadmium;
                     locus is variably amplified in different strains, with two
                     copies, CUP1-1 and CUP1-2, in the genomic sequence
                     reference strain S288C; CUP1-2 has a paralog, CUP1-1, that
                     arose from a segmental duplication"
                     /codon_start=1
                     /product="metallothionein CUP1"
                     /protein_id="NP_011920.1"
                     /db_xref="GI:6321844"
                     /db_xref="SGD:S000001097"
                     /db_xref="GeneID:856452"
                     /translation="MFSELINFQNEGHECQCQCGSCKNNEQCQKSCSCPTGCNSDDKC
                     PCGNKSEETKKSCCSGK"
     rep_origin      214718..215183
                     /note="ARS811;
                     Putative replication origin; identified in multiple array
                     studies, not yet confirmed by plasmid-based assay"
                     /db_xref="SGD:S000130148"
     gene            complement(<215183..>217834)
                     /gene="RSC30"
                     /locus_tag="YHR056C"
                     /db_xref="GeneID:856453"
     mRNA            complement(<215183..>217834)
                     /gene="RSC30"
                     /locus_tag="YHR056C"
                     /product="Rsc30p"
                     /transcript_id="NM_001179186.2"
                     /db_xref="GI:330443581"
                     /db_xref="GeneID:856453"
     CDS             complement(215183..217834)
                     /gene="RSC30"
                     /locus_tag="YHR056C"
                     /note="Component of the RSC chromatin remodeling complex;
                     non-essential gene required for regulation of ribosomal
                     protein genes and the cell wall/stress response; null
                     mutants are osmosensitive; RSC30 has a paralog, RSC3, that
                     arose from the whole genome duplication"
                     /codon_start=1
                     /product="Rsc30p"
                     /protein_id="NP_011923.2"
                     /db_xref="GI:41629685"
                     /db_xref="SGD:S000001098"
                     /db_xref="GeneID:856453"
                     /translation="MMDMQVRKVRKPPACTQCRKRKIGCDRAKPICGNCVKYNKPDCF
                     YPDGPGKMVAVPSASGMSTHGNGQGSNHFSQGNGVNQKNVMIQTQYPIMQTSIEAFNF
                     SFNPSVDTAMQWTKAASYQNNNTNNNTAPRQNSSTVSSNVHGNTIVRSDSPDVPSMDQ
                     IREYNTRLQLVNAQSFDYTDNPYSFNVGINQDSAVFDLMTSPFTQEEVLIKEIDFLKN
                     KLLDLQSLQLKSLKEKSNLNADNTTANKINKTGENSKKGKVDGKRAGFDHQTSRTSQS
                     SQKYFTALTITDVQSLVQVKPLKDTPNYLFTKNFIIFRDHYLFKFYNILHDICHINQF
                     KVSPPNNKNHQQYMEVCKVNFPPKAIIIETLNSESLNNLNIEEFLPIFDKTLLLEFVH
                     NSFPNGDTCPSFSTVDLPLSQLTKLGELTVLLLLLNDSMTLFNKQAINNHVSALMNNL
                     RLIRSQITLINLEYYDQETIKFIAITKFYESLYMHDDHKSSLDEDLSCLLSFQIKDFK
                     LFHFLKKMYYSRHSLLGQSSFMVPAAENLSPIPASIDTNDIPLIANDLKLLETQAKLI
                     NILQGVPFYLPVNLTKIESLLETLTMGVSNTVDLYFHDNEVRKEWKDTLNFINTIVYT
                     NFFLFVQNESSLSMAVQHSSNNNKTSNSERCAKDLMKIISNMHIFYSITFNFIFPIKS
                     IKSFSSGNNRFHSNGKEFLFANHFIEILQNFIAITFAIFQRCEVILYDEFYKNLSNEE
                     INVQLLLIHDKILEILKKIEIIVSFLRDEMNSNGSFKSIKGFNKVLNLIKYMLRFSKK
                     KQNFARNSDNNNVTDYSQSAKNKNVLLKFPVSELNRIYLKFKEISDFLMEREVVQRSI
                     IIDKDLESDNLGITTANFNDFYDAFYN"
     gene            complement(<218226..>218843)
                     /gene="CPR2"
                     /locus_tag="YHR057C"
                     /gene_synonym="CYP2"
                     /db_xref="GeneID:856454"
     mRNA            complement(<218226..>218843)
                     /gene="CPR2"
                     /locus_tag="YHR057C"
                     /gene_synonym="CYP2"
                     /product="peptidylprolyl isomerase CPR2"
                     /transcript_id="NM_001179187.1"
                     /db_xref="GI:296145434"
                     /db_xref="GeneID:856454"
     CDS             complement(218226..218843)
                     /gene="CPR2"
                     /locus_tag="YHR057C"
                     /gene_synonym="CYP2"
                     /EC_number="5.2.1.8"
                     /note="Peptidyl-prolyl cis-trans isomerase (cyclophilin);
                     catalyzes the cis-trans isomerization of peptide bonds
                     N-terminal to proline residues; has a potential role in
                     the secretory pathway; CPR2 has a paralog, CPR5, that
                     arose from the whole genome duplication; suppresses
                     toxicity of slow-folding human Z-type alpha1-antitrypsin
                     variant associated with liver cirrhosis and emphysema"
                     /codon_start=1
                     /product="peptidylprolyl isomerase CPR2"
                     /protein_id="NP_011924.1"
                     /db_xref="GI:6321848"
                     /db_xref="SGD:S000001099"
                     /db_xref="GeneID:856454"
                     /translation="MKFSGLWCWLLLFLSVNVIASDVGELIDQDDEVITQKVFFDIEH
                     GEEKVGRIVIGLYGKVCPKTAKNFYKLSTTTNSKKGFIGSTFHRVIPNFMVQGGDFTD
                     GTGVGGKSIYGDTFPDENFTLKHDRKGRLSMANRGKDTNGSQFFITTTEEASWLDGKH
                     VVFGQVVDGMDVVNYIQHVSRDANDKPLEAVKIAKCGEWTPELSS"
     gene            complement(<218997..>219884)
                     /gene="MED6"
                     /locus_tag="YHR058C"
                     /db_xref="GeneID:856455"
     mRNA            complement(<218997..>219884)
                     /gene="MED6"
                     /locus_tag="YHR058C"
                     /product="Med6p"
                     /transcript_id="NM_001179188.1"
                     /db_xref="GI:296145435"
                     /db_xref="GeneID:856455"
     CDS             complement(218997..219884)
                     /gene="MED6"
                     /locus_tag="YHR058C"
                     /note="Subunit of the RNA polymerase II mediator complex;
                     associates with core polymerase subunits to form the RNA
                     polymerase II holoenzyme; essential for transcriptional
                     regulation; protein abundance increases in response to DNA
                     replication stress"
                     /codon_start=1
                     /product="Med6p"
                     /protein_id="NP_011925.1"
                     /db_xref="GI:6321849"
                     /db_xref="SGD:S000001100"
                     /db_xref="GeneID:856455"
                     /translation="MNVTPLDELQWKSPEWIQVFGLRTENVLDYFAESPFFDKTSNNQ
                     VIKMQRQFSQLNDPNAAVNMTQNIMTLPDGKNGNLEEEFAYVDPARRQILFKYPMYMQ
                     LEEELMKLDGTEYVLSSVREPDFWVIRKQRRTNNSGVGSAKGPEIIPLQDYYIIGANI
                     YQSPTIFKIVQSRLMSTSYHLNSTLESLYDLIEFQPSQGVHYKVPTDTSTTATAATNG
                     NNAGGGSNKSSVRPTGGANMATVPSTTNVNMTVNTMGTGGQTIDNGTGRTGNGNMGIT
                     TEMLDKLMVTSIRSTPNYI"
     gene            <220108..>220500
                     /gene="FYV4"
                     /locus_tag="YHR059W"
                     /db_xref="GeneID:856456"
     mRNA            <220108..>220500
                     /gene="FYV4"
                     /locus_tag="YHR059W"
                     /product="Fyv4p"
                     /transcript_id="NM_001179189.1"
                     /db_xref="GI:296145436"
                     /db_xref="GeneID:856456"
     CDS             220108..220500
                     /gene="FYV4"
                     /locus_tag="YHR059W"
                     /note="hypothetical protein; required for survival upon
                     exposure to K1 killer toxin"
                     /codon_start=1
                     /product="Fyv4p"
                     /protein_id="NP_011926.1"
                     /db_xref="GI:6321850"
                     /db_xref="SGD:S000001101"
                     /db_xref="GeneID:856456"
                     /translation="MIPSRISHKFPLFLRSSLAAPKAAYRFSSTIPKPSDQVPDVDAF
                     LNKIGRNCNELKDTFENNWNNLFQWDSKILKEKGVNIQQRKYILKQVHNYRNNRPIHE
                     IKLGKKSFFGGERKRKAFTAKWKAENKQ"
     gene            <220725..>221270
                     /gene="VMA22"
                     /locus_tag="YHR060W"
                     /gene_synonym="CEV1; VPH6"
                     /db_xref="GeneID:856457"
     mRNA            <220725..>221270
                     /gene="VMA22"
                     /locus_tag="YHR060W"
                     /gene_synonym="CEV1; VPH6"
                     /product="Vma22p"
                     /transcript_id="NM_001179190.1"
                     /db_xref="GI:296145437"
                     /db_xref="GeneID:856457"
     CDS             220725..221270
                     /gene="VMA22"
                     /locus_tag="YHR060W"
                     /gene_synonym="CEV1; VPH6"
                     /note="Protein that is required for vacuolar H+-ATPase
                     (V-ATPase) function; peripheral membrane protein; not an
                     actual component of the V-ATPase complex; functions in the
                     assembly of the V-ATPase; localized to the yeast
                     endoplasmic reticulum (ER)"
                     /codon_start=1
                     /product="Vma22p"
                     /protein_id="NP_011927.1"
                     /db_xref="GI:6321851"
                     /db_xref="SGD:S000001102"
                     /db_xref="GeneID:856457"
                     /translation="MSETRMAQNMDTTDEQYLRLIELLSNYDSTLEQLQKGFQDGYIQ
                     LSRSNYYNKDSLRGNYGEDYWDETYIGQLMATVEEKNSKVVVEIVKRKAQDKQEKKEE
                     EDNKLTQRKKGTKPEKQKTQSHKLKQDYDPILMFGGVLSVPSSLRQSQTSFKGCIPLI
                     AQLINYKNEILTLVETLSEQE"
     gene            complement(<221534..>222478)
                     /gene="GIC1"
                     /locus_tag="YHR061C"
                     /db_xref="GeneID:856458"
     mRNA            complement(<221534..>222478)
                     /gene="GIC1"
                     /locus_tag="YHR061C"
                     /product="Gic1p"
                     /transcript_id="NM_001179191.1"
                     /db_xref="GI:296145438"
                     /db_xref="GeneID:856458"
     CDS             complement(221534..222478)
                     /gene="GIC1"
                     /locus_tag="YHR061C"
                     /note="Protein involved in initiation of budding and
                     cellular polarization; interacts with Cdc42p via the
                     Cdc42/Rac-interactive binding (CRIB) domain; relocalizes
                     from bud neck to nucleus upon DNA replication stress; GIC1
                     has a paralog, GIC2, that arose from the whole genome
                     duplication"
                     /codon_start=1
                     /product="Gic1p"
                     /protein_id="NP_011928.1"
                     /db_xref="GI:6321852"
                     /db_xref="SGD:S000001103"
                     /db_xref="GeneID:856458"
                     /translation="MTEGKRLQQMELPQMKSIWIDEDQEMEKLYGFQVRQRFMNGPST
                     DSDEDADEDLGIVLVDSKKLALPNKNNIKLPPLPNYMTINPNINSNHKSLTNKKKNFL
                     GMFKKKDLLSRRHGSAKTAKQSSISTPFDFHHISHANGKREDNPLESHEEKHDVESLV
                     KFTSLAPQPRPDSNVSSKYSNVVMNDSSRIVSSSTIATTMDSHHDGNETNNTPNGNKQ
                     LDSPTDLEMTLEDLRNYTFPSVLGDSVSEKTNPSSPSVSSFSGKFKPRELSALHTPEL
                     GNCFNVDQSLNSPGNRISVDDVLKFYYQCSETSTPRNT"
     gene            complement(<222877..>223758)
                     /gene="RPP1"
                     /locus_tag="YHR062C"
                     /db_xref="GeneID:856459"
     mRNA            complement(<222877..>223758)
                     /gene="RPP1"
                     /locus_tag="YHR062C"
                     /product="Rpp1p"
                     /transcript_id="NM_001179192.1"
                     /db_xref="GI:296145439"
                     /db_xref="GeneID:856459"
     CDS             complement(222877..223758)
                     /gene="RPP1"
                     /locus_tag="YHR062C"
                     /EC_number="3.1.26.5"
                     /note="Subunit of both RNase MRP and nuclear RNase P;
                     RNase MRP cleaves pre-rRNA, while nuclear RNase P cleaves
                     tRNA precursors to generate mature 5' ends and facilitates
                     turnover of nuclear RNAs; relocalizes to the cytosol in
                     response to hypoxia"
                     /codon_start=1
                     /product="Rpp1p"
                     /protein_id="NP_011929.1"
                     /db_xref="GI:6321853"
                     /db_xref="SGD:S000001104"
                     /db_xref="GeneID:856459"
                     /translation="MLVDLNVPWPQNSYADKVTSQAVNNLIKTLSTLHMLGYTHIAIN
                     FTVNHSEKFPNDVKLLNPIDIKRRFGELMDRTGLKLYSRITLIIDDPSKGQSLSKISQ
                     AFDIVAALPISEKGLTLSTTNLDIDLLTFQYGSRLPTFLKHKSICSCVNRGVKLEIVY
                     GYALRDVQARRQFVSNVRSVIRSSRSRGIVIGSGAMSPLECRNILGVTSLIKNLGLPS
                     DRCSKAMGDLASLVLLNGRLRNKSHKQTIVTGGGSGNGDDVVNDVQGIDDVQTIKVVK
                     RSMDAEQLGHASKRHKP"
     gene            complement(<224030..>225169)
                     /gene="PAN5"
                     /locus_tag="YHR063C"
                     /db_xref="GeneID:856460"
     mRNA            complement(<224030..>225169)
                     /gene="PAN5"
                     /locus_tag="YHR063C"
                     /product="2-dehydropantoate 2-reductase PAN5"
                     /transcript_id="NM_001179193.1"
                     /db_xref="GI:296145440"
                     /db_xref="GeneID:856460"
     CDS             complement(224030..225169)
                     /gene="PAN5"
                     /locus_tag="YHR063C"
                     /EC_number="1.1.1.169"
                     /note="2-dehydropantoate 2-reductase; part of the
                     pantothenic acid pathway, structurally homologous to E.
                     coli panE"
                     /codon_start=1
                     /product="2-dehydropantoate 2-reductase PAN5"
                     /protein_id="NP_011930.1"
                     /db_xref="GI:6321854"
                     /db_xref="SGD:S000001105"
                     /db_xref="GeneID:856460"
                     /translation="MTAPHRSTIHILGLGAMGTVLAVDLLRFTNALVVPLFRSQERLA
                     QFQKTNGNNISIRKLYLEGSPIFSYPVEKCECPETFSKKPIDNLVVTTKTYQTKEALA
                     PYLPYINKNTNLILIQNGLGVLELLREEIFTDSKNRPHLFQGVISHGVYQDKAGVFNH
                     AGWAGMKIAKLPWTEEEMIQKKSVVEDDAANNSLVKLLTEPKFAKEFGIEHSTYQEML
                     FGQLFKFLVNACMNPVTAILDCVNGEMKASCGPVFTSIIDECLQILRVAYRPLFQYHE
                     KYSGNEEYPEMDVNAVLTTDNMVSEVTRIGCDINSRNSSSMRQDTLFLRDIEIEYING
                     YVVKLADNLNLDPNCCKVNKTIGELATMRLALNRSRSINGDWRKD"
     gene            complement(<225525..>227141)
                     /gene="SSZ1"
                     /locus_tag="YHR064C"
                     /gene_synonym="PDR13"
                     /db_xref="GeneID:856461"
     mRNA            complement(<225525..>227141)
                     /gene="SSZ1"
                     /locus_tag="YHR064C"
                     /gene_synonym="PDR13"
                     /product="Ssz1p"
                     /transcript_id="NM_001179194.1"
                     /db_xref="GI:296145441"
                     /db_xref="GeneID:856461"
     CDS             complement(225525..227141)
                     /gene="SSZ1"
                     /locus_tag="YHR064C"
                     /gene_synonym="PDR13"
                     /note="Hsp70 protein that interacts with Zuo1p (a DnaJ
                     homolog); interacts with Zuo1p to form a
                     ribosome-associated complex that binds the ribosome via
                     the Zuo1p subunit; also involved in pleiotropic drug
                     resistance via sequential activation of PDR1 and PDR5;
                     binds ATP"
                     /codon_start=1
                     /product="Ssz1p"
                     /protein_id="NP_011931.2"
                     /db_xref="GI:37362658"
                     /db_xref="SGD:S000001106"
                     /db_xref="GeneID:856461"
                     /translation="MSSPVIGITFGNTSSSIAYINPKNDVDVIANPDGERAIPSALSY
                     VGEDEYHGGQALQQLIRNPKNTIINFRDFIGLPFDKCDVSKCANGAPAVEVDGKVGFV
                     ISRGEGKEEKLTVDEVVSRHLNRLKLAAEDYIGSAVKEAVLTVPTNFSEEQKTALKAS
                     AAKIGLQIVQFINEPSAALLAHAEQFPFEKDVNVVVADFGGIRSDAAVIAVRNGIFTI
                     LATAHDLSLGGDNLDTELVEYFASEFQKKYQANPRKNARSLAKLKANSSITKKTLSNA
                     TSATISIDSLADGFDYHASINRMRYELVANKVFAQFSSFVDSVIAKAELDPLDIDAVL
                     LTGGVSFTPKLTTNLEYTLPESVEILGPQNKNASNNPNELAASGAALQARLISDYDAD
                     ELAEALQPVIVNTPHLKKPIGLIGAKGEFHPVLLAETSFPVQKKLTLKQAKGDFLIGV
                     YEGDHHIEEKTLEPIPKEENAEEDDESEWSDDEPEVVREKLYTLGTKLMELGIKNANG
                     VEIIFNINKDGALRVTARDLKTGNAVKGEL"
     gene            complement(<227532..>229037)
                     /gene="RRP3"
                     /locus_tag="YHR065C"
                     /db_xref="GeneID:856462"
     mRNA            complement(<227532..>229037)
                     /gene="RRP3"
                     /locus_tag="YHR065C"
                     /product="RNA-dependent ATPase RRP3"
                     /transcript_id="NM_001179195.1"
                     /db_xref="GI:296145442"
                     /db_xref="GeneID:856462"
     CDS             complement(227532..229037)
                     /gene="RRP3"
                     /locus_tag="YHR065C"
                     /EC_number="3.6.4.-"
                     /EC_number="3.6.4.13"
                     /note="Protein involved in rRNA processing; required for
                     maturation of the 35S primary transcript of pre-rRNA and
                     for cleavage leading to mature 18S rRNA; homologous to
                     eIF-4a, which is a DEAD box RNA-dependent ATPase with
                     helicase activity"
                     /codon_start=1
                     /product="RNA-dependent ATPase RRP3"
                     /protein_id="NP_011932.2"
                     /db_xref="GI:37362659"
                     /db_xref="SGD:S000001107"
                     /db_xref="GeneID:856462"
                     /translation="MSKIVKRKEKKANDELTSLAEKIRAKALENQKKLIEAEKEGGSE
                     SDSEEDATAEKKKVLKSKSKSTVSTQNENTNEDESFESFSELNLVPELIQACKNLNYS
                     KPTPIQSKAIPPALEGHDIIGLAQTGSGKTAAFAIPILNRLWHDQEPYYACILAPTRE
                     LAQQIKETFDSLGSLMGVRSTCIVGGMNMMDQARDLMRKPHIIIATPGRLMDHLENTK
                     GFSLRKLKFLVMDEADRLLDMEFGPVLDRILKIIPTQERTTYLFSATMTSKIDKLQRA
                     SLTNPVKCAVSNKYQTVDTLVQTLMVVPGGLKNTYLIYLLNEFIGKTMIIFTRTKANA
                     ERLSGLCNLLEFSATALHGDLNQNQRMGSLDLFKAGKRSILVATDVAARGLDIPSVDI
                     VVNYDIPVDSKSYIHRVGRTARAGRSGKSISLVSQYDLELILRIEEVLGKKLPKESVD
                     KNIILTLRDSVDKANGEVVMEMNRRNKEKIARGKGRRGRMMTRENMDMGER"
     gene            <229335..>230696
                     /gene="SSF1"
                     /locus_tag="YHR066W"
                     /db_xref="GeneID:856463"
     mRNA            <229335..>230696
                     /gene="SSF1"
                     /locus_tag="YHR066W"
                     /product="Ssf1p"
                     /transcript_id="NM_001179196.1"
                     /db_xref="GI:296145443"
                     /db_xref="GeneID:856463"
     CDS             229335..230696
                     /gene="SSF1"
                     /locus_tag="YHR066W"
                     /note="Constituent of 66S pre-ribosomal particles;
                     required for ribosomal large subunit maturation;
                     functionally redundant with Ssf2p; member of the Brix
                     family; SSF1 has a paralog, SSF2, that arose from the
                     whole genome duplication"
                     /codon_start=1
                     /product="Ssf1p"
                     /protein_id="NP_011933.1"
                     /db_xref="GI:6321857"
                     /db_xref="SGD:S000001108"
                     /db_xref="GeneID:856463"
                     /translation="MAKRRQKKRTHAQLTPEQEQGIPKSMVIRVGQTSLANHSLNQLV
                     KDFRQIMQPHTAIKLKERKSNKLKDFVVMCGPLGVTHLFMFTQSEKTGNVSLKIARTP
                     QGPTVTFQVLDYSLGRDIKKFLKRPKSLNNDDVLNPPLLVLNGFSTSKRSGEDDQDVN
                     VEKVIVSMFQNIFPPLNPARTSLNSIKRVFMINKDRETGEISMRHYFIDIREVEISRN
                     LKRLYKAKNNLSKTVPNLHRKEDISSLILDHDLGAYTSESEIEDDAIVRVVDNQDVKA
                     KHSQSLKSQRTPVEKKDNKEREKETEEEDVEMEEPKPSENLQPTPRKKAIKLTELGPR
                     LTLKLVKIEEGICSGKVLHHEFVQKSSEEIKALEKRHAAKMRLKEQRKKEQEENIAKK
                     KAVKDAKKQRKLERRKARAAEGGEGQGKDDAMSDDESSSSDSEHYGSVPEDLDSDLFS
                     EVE"
     gene            <230970..>231812
                     /gene="HTD2"
                     /locus_tag="YHR067W"
                     /gene_synonym="RMD12"
                     /db_xref="GeneID:856464"
     mRNA            <230970..>231812
                     /gene="HTD2"
                     /locus_tag="YHR067W"
                     /gene_synonym="RMD12"
                     /product="hydroxyacyl-thioester dehydratase HTD2"
                     /transcript_id="NM_001179197.1"
                     /db_xref="GI:296145444"
                     /db_xref="GeneID:856464"
     CDS             230970..231812
                     /gene="HTD2"
                     /locus_tag="YHR067W"
                     /gene_synonym="RMD12"
                     /EC_number="4.2.1.-"
                     /note="Mitochondrial 3-hydroxyacyl-thioester dehydratase;
                     involved in fatty acid biosynthesis, required for
                     respiratory growth and for normal mitochondrial
                     morphology"
                     /codon_start=1
                     /product="hydroxyacyl-thioester dehydratase HTD2"
                     /protein_id="NP_011934.1"
                     /db_xref="GI:6321858"
                     /db_xref="SGD:S000001109"
                     /db_xref="GeneID:856464"
                     /translation="MKSKTWIFRDVLSSHRTKAFDSLLCRRLPVSKATKHLQLGEHFL
                     FFPPSFEKLDRDGYFNYQNPASLLGNPDLRYRRRIWGQGELVQYLPVTLDQEYTCHES
                     IKYVKKIRDEHVVCIERTLLQERPENVSSPMDICLFERRVLMYTNSPANKTAVKMPVG
                     EENYKILKNFTVTDMDIVAYGQMSLNPHRIHWDKEYSRYVEGYDDIIMQGPFSVQLLQ
                     KCIQPFLEQPIRQLRYRNLNYIYPNTTLSICQSLSSSSGMYTFQIRDLQKANLVYMKA
                     DVFC"
     gene            <232133..>233296
                     /gene="DYS1"
                     /locus_tag="YHR068W"
                     /db_xref="GeneID:856465"
     mRNA            <232133..>233296
                     /gene="DYS1"
                     /locus_tag="YHR068W"
                     /product="Dys1p"
                     /transcript_id="NM_001179198.1"
                     /db_xref="GI:296145445"
                     /db_xref="GeneID:856465"
     CDS             232133..233296
                     /gene="DYS1"
                     /locus_tag="YHR068W"
                     /EC_number="2.5.1.46"
                     /note="Deoxyhypusine synthase; catalyzes formation of
                     deoxyhypusine, the first step in hypusine biosynthesis;
                     triggers posttranslational hypusination of translation
                     elongation factor eIF-5A and regulates its intracellular
                     levels; tetrameric"
                     /codon_start=1
                     /product="Dys1p"
                     /protein_id="NP_011935.1"
                     /db_xref="GI:6321859"
                     /db_xref="SGD:S000001110"
                     /db_xref="GeneID:856465"
                     /translation="MSDINEKLPELLQDAVLKASVPIPDDFVKVQGIDYSKPEATNMR
                     ATDLIEAMKTMGFQASSVGTACEIIDSMRSWRGKHIDELDDHEKKGCFDEEGYQKTTI
                     FMGYTSNLISSGVRETLRYLVQHKMVDAVVTSAGGVEEDLIKCLAPTYLGEFALKGKS
                     LRDQGMNRIGNLLVPNDNYCKFEEWIVPILDKMLEEQDEYVKKHGADCLEANQDVDSP
                     IWTPSKMIDRFGKEINDESSVLYWAHKNKIPIFCPSLTDGSIGDMLFFHTFKASPKQL
                     RVDIVGDIRKINSMSMAAYRAGMIILGGGLIKHHIANACLMRNGADYAVYINTGQEYD
                     GSDAGARPDEAVSWGKIKAEAKSVKLFADVTTVLPLIVAATFASGKPIKKVKN"
     gene            complement(<233579..>234658)
                     /gene="RRP4"
                     /locus_tag="YHR069C"
                     /db_xref="GeneID:856466"
     mRNA            complement(<233579..>234658)
                     /gene="RRP4"
                     /locus_tag="YHR069C"
                     /product="Rrp4p"
                     /transcript_id="NM_001179199.1"
                     /db_xref="GI:296145446"
                     /db_xref="GeneID:856466"
     CDS             complement(233579..234658)
                     /gene="RRP4"
                     /locus_tag="YHR069C"
                     /note="Exosome non-catalytic core component; involved in
                     3'-5' RNA processing and degradation in both the nucleus
                     and the cytoplasm; predicted to contain RNA binding
                     domains; has similarity to human hRrp4p (EXOSC2)"
                     /codon_start=1
                     /product="Rrp4p"
                     /protein_id="NP_011936.1"
                     /db_xref="GI:6321860"
                     /db_xref="SGD:S000001111"
                     /db_xref="GeneID:856466"
                     /translation="MSEVITITKRNGAFQNSSNLSYNNTGISDDENDEEDIYMHDVNS
                     ASKSESDSQIVTPGELVTDDPIWMRGHGTYFLDNMTYSSVAGTVSRVNRLLSVIPLKG
                     RYAPETGDHVVGRIAEVGNKRWKVDIGGKQHAVLMLGSVNLPGGILRRKSESDELQMR
                     SFLKEGDLLNAEVQSLFQDGSASLHTRSLKYGKLRNGMFCQVPSSLIVRAKNHTHNLP
                     GNITVVLGVNGYIWLRKTSQMDLARDTPSANNSSSIKSTGPTGAVSLNPSITRLEEES
                     SWQIYSDENDPSISNNIRQAICRYANVIKALAFCEIGITQQRIVSAYEASMVYSNVGE
                     LIEKNVMESIGSDILTAEKMRGNGN"
     gene            <234881..>236380
                     /gene="TRM5"
                     /locus_tag="YHR070W"
                     /db_xref="GeneID:856467"
     mRNA            <234881..>236380
                     /gene="TRM5"
                     /locus_tag="YHR070W"
                     /product="Trm5p"
                     /transcript_id="NM_001179200.1"
                     /db_xref="GI:296145447"
                     /db_xref="GeneID:856467"
     CDS             234881..236380
                     /gene="TRM5"
                     /locus_tag="YHR070W"
                     /EC_number="2.1.1.228"
                     /note="tRNA(m(1)G37)methyltransferase; methylates a tRNA
                     base adjacent to the anticodon that has a role in
                     prevention of frameshifting; highly conserved across
                     Archaea, Bacteria, and Eukarya"
                     /codon_start=1
                     /product="Trm5p"
                     /protein_id="NP_011937.1"
                     /db_xref="GI:6321861"
                     /db_xref="SGD:S000001112"
                     /db_xref="GeneID:856467"
                     /translation="MKIALPVFQKFNRLISSCKMSGVFPYNPPVNRQMRELDRSFFIT
                     KIPMCAVKFPEPKNISVFSKNFKNCILRVPRIPHVVKLNSSKPKDELTSVQNKKLKTA
                     DGNNTPVTKGVLLHESIHSVEDAYGKLPEDALAFLKENSAEIVPHEYVLDYDFWKAEE
                     ILRAVLPEQFLEEVPTGFTITGHIAHLNLRTEFKPFDSLIGQVILDKNNKIECVVDKV
                     SSIATQFRTFPMKVIAGKSDSLVVEQKESNCTFKFDFSKVYWNSRLHTEHERLVKQYF
                     QPGQVVCDVFAGVGPFAVPAGKKDVIVLANDLNPESYKYLKENIALNKVAKTVKSFNM
                     DGADFIRQSPQLLQQWIQDEEGGKITIPLPLKKRHRSQQHNDQQPPQPRTKELIIPSH
                     ISHYVMNLPDSAISFLGNFRGIFAAHTKGATDTIQMPWVHVHCFEKYPPGDQVTEDEL
                     HARVHARIIAALKVTADDLPLNAVSLHLVRKVAPTKPMYCASFQLPANV"
     gene            <237004..>237693
                     /gene="PCL5"
                     /locus_tag="YHR071W"
                     /db_xref="GeneID:856468"
     mRNA            <237004..>237693
                     /gene="PCL5"
                     /locus_tag="YHR071W"
                     /product="Pcl5p"
                     /transcript_id="NM_001179201.1"
                     /db_xref="GI:296145448"
                     /db_xref="GeneID:856468"
     CDS             237004..237693
                     /gene="PCL5"
                     /locus_tag="YHR071W"
                     /note="Cyclin; interacts with and phosphorylated by Pho85p
                     cyclin-dependent kinase (Cdk), induced by Gcn4p at level
                     of transcription, specifically required for Gcn4p
                     degradation, may be sensor of cellular protein
                     biosynthetic capacity"
                     /codon_start=1
                     /product="Pcl5p"
                     /protein_id="NP_011938.1"
                     /db_xref="GI:6321862"
                     /db_xref="SGD:S000001113"
                     /db_xref="GeneID:856468"
                     /translation="MDGNHRFTPDSKEFNTVVKSKESSTGRNPYQTPPLEHNGTHHQT
                     NYSRKKTNLAIIISNFLSEISRPLSNGKINNSTHNILKFLNEVLKRSKCSKENAVLAT
                     FYFQKIHQSRGVRDESSLPEFSHCSRRIFLCCLILSHKFLNDNTYSMKNWQIISGLHA
                     KDLSLMERWCLGKLNYELAIPYDEFLLWETNTLMKAKLRVGTPANAPVKRPRESDNDY
                     DANSWKQIKSC"
     gene            complement(237848..237939)
                     /locus_tag="tF(GAA)H1"
                     /db_xref="GeneID:856469"
     tRNA            complement(join(237848..237883,237903..237939))
                     /locus_tag="tF(GAA)H1"
                     /product="tRNA-Phe"
                     /note="Phenylalanine tRNA (tRNA-Phe), predicted by
                     tRNAscan-SE analysis; tF(GAA)H1"
                     /db_xref="SGD:S000006566"
                     /db_xref="GeneID:856469"
     gene            <239098..>241293
                     /gene="ERG7"
                     /locus_tag="YHR072W"
                     /db_xref="GeneID:856470"
     mRNA            <239098..>241293
                     /gene="ERG7"
                     /locus_tag="YHR072W"
                     /product="lanosterol synthase ERG7"
                     /transcript_id="NM_001179202.2"
                     /db_xref="GI:330443582"
                     /db_xref="GeneID:856470"
     CDS             239098..241293
                     /gene="ERG7"
                     /locus_tag="YHR072W"
                     /EC_number="5.4.99.7"
                     /note="Lanosterol synthase; an essential enzyme that
                     catalyzes the cyclization of squalene 2,3-epoxide, a step
                     in ergosterol biosynthesis"
                     /codon_start=1
                     /product="lanosterol synthase ERG7"
                     /protein_id="NP_011939.2"
                     /db_xref="GI:330443583"
                     /db_xref="SGD:S000001114"
                     /db_xref="GeneID:856470"
                     /translation="MTEFYSDTIGLPKTDPRLWRLRTDELGRESWEYLTPQQAANDPP
                     STFTQWLLQDPKFPQPHPERNKHSPDFSAFDACHNGASFFKLLQEPDSGIFPCQYKGP
                     MFMTIGYVAVNYIAGIEIPEHERIELIRYIVNTAHPVDGGWGLHSVDKSTVFGTVLNY
                     VILRLLGLPKDHPVCAKARSTLLRLGGAIGSPHWGKIWLSALNLYKWEGVNPAPPETW
                     LLPYSLPMHPGRWWVHTRGVYIPVSYLSLVKFSCPMTPLLEELRNEIYTKPFDKINFS
                     KNRNTVCGVDLYYPHSTTLNIANSLVVFYEKYLRNRFIYSLSKKKVYDLIKTELQNTD
                     SLCIAPVNQAFCALVTLIEEGVDSEAFQRLQYRFKDALFHGPQGMTIMGTNGVQTWDC
                     AFAIQYFFVAGLAERPEFYNTIVSAYKFLCHAQFDTECVPGSYRDKRKGAWGFSTKTQ
                     GYTVADCTAEAIKAIIMVKNSPVFSEVHHMISSERLFEGIDVLLNLQNIGSFEYGSFA
                     TYEKIKAPLAMETLNPAEVFGNIMVEYPYVECTDSSVLGLTYFHKYFDYRKEEIRTRI
                     RIAIEFIKKSQLPDGSWYGSWGICFTYAGMFALEALHTVGETYENSSTVRKGCDFLVS
                     KQMKDGGWGESMKSSELHSYVDSEKSLVVQTAWALIALLFAEYPNKEVIDRGIDLLKN
                     RQEESGEWKFESVEGVFNHSCAIEYPSYRFLFPIKALGMYSRAYETHTL"
     gene            <241664..>241840
                     /gene="NOP10"
                     /locus_tag="YHR072W-A"
                     /db_xref="GeneID:856471"
     mRNA            <241664..>241840
                     /gene="NOP10"
                     /locus_tag="YHR072W-A"
                     /product="Nop10p"
                     /transcript_id="NM_001184438.1"
                     /db_xref="GI:296145450"
                     /db_xref="GeneID:856471"
     CDS             241664..241840
                     /gene="NOP10"
                     /locus_tag="YHR072W-A"
                     /note="Subunit of box H/ACA snoRNP complex; required for
                     pseudouridylation and processing of pre-18S rRNA"
                     /codon_start=1
                     /product="Nop10p"
                     /protein_id="NP_058135.1"
                     /db_xref="GI:7839181"
                     /db_xref="SGD:S000007455"
                     /db_xref="GeneID:856471"
                     /translation="MHLMYTLGPDGKRIYTLKKVTESGEITKSAHPARFSPDDKYSRQ
                     RVTLKKRFGLVPGQ"
     gene            <242582..>245572
                     /gene="OSH3"
                     /locus_tag="YHR073W"
                     /db_xref="GeneID:856472"
     mRNA            <242582..>245572
                     /gene="OSH3"
                     /locus_tag="YHR073W"
                     /product="oxysterol-binding protein related protein OSH3"
                     /transcript_id="NM_001179203.1"
                     /db_xref="GI:296145451"
                     /db_xref="GeneID:856472"
     CDS             242582..245572
                     /gene="OSH3"
                     /locus_tag="YHR073W"
                     /note="Member of an oxysterol-binding protein family; this
                     family has seven members in S. cerevisiae; family members
                     have overlapping, redundant functions in sterol metabolism
                     and collectively perform a function essential for
                     viability"
                     /codon_start=1
                     /product="oxysterol-binding protein related protein OSH3"
                     /protein_id="NP_011940.1"
                     /db_xref="GI:6321864"
                     /db_xref="SGD:S000001115"
                     /db_xref="GeneID:856472"
                     /translation="METIDIQNRSFVVRWVKCGRGDVINYQIKPLKKSIEVGIYKKLK
                     SSVDDHASAVHIAPDTKTLLDYTTKSLLHKGSSSNIEEHHRRSSQHSHSSSNGSDNKR
                     KERSYSSLSISGIQQQSQEIPLREKLSASGFTLVKRVGNVSGNTMVQGDLEVKDTDYY
                     YAFILDNSSSKNAKKKILFNASVINGDNQSMISTRSTPPARPTALSRTSTQQDMLFRV
                     GQGRYLQGYLLKKRRKRLQGFKKRFFTLDFRYGTLSYYLNDHNQTCRGEIVISLSSVS
                     ANKKDKIIIIDSGMEVWVLKATTKENWQSWVDALQTCFDDQFEDKDTSTLEENPDILD
                     DDKEVINKSSPQDHDHLTPTATTKSALSHRQHTQKDMDDIYVPLPSESYATFSMNLRL
                     IQQRLEQCKKDSLSYKPTTLHQRSEGLNGTHSSSSVFTNNRVSSFNHSSSGMTSSDSL
                     ASEEVPSNKTYIEHALYNQLADLEVFVSRFVTQGEVLFKDHQILCKKAKDTRVSLTSY
                     LSENDEFFDAEEEISRGVIILPDTEDDINNIVEETPLLGKSDQNEFTKEVQLSGSEQI
                     ASSSVESYTTNDENHSRKHLKNRHKNRRRGHPHHQKTKSAQSSTETFTSKDLFALSYP
                     KSVTRRNDIPEAAASPPSLLSFLRKNVGKDLSSIAMPVTSNEPISILQLISETFEYAP
                     LLTKATQRPDPITFVSAFAISFLSIYRDKTRTLRKPFNPLLAETFELIREDMGFRLIS
                     EKVSHRPPVFAFFAEHLDWECSYTVTPSQKFWGKSIELNNEGILRLKFKTTGELFEWT
                     QPTTILKNLIAGERYMEPVNEFEVHSSKGDKSHILFDKAGMFSGRSEGFKVSIIPPPS
                     SNRKKETLAGKWTQSLANETTHETIWEVGDLVSNPKKKYGFTKFTANLNEITEIEKGN
                     LPPTDSRLRPDIRAYEEGNVDKAEEWKLKLEQLQRERRNKGQDVEPKYFEKVSKNEWK
                     YITGPKSYWERRKKHDWSDISQLW"
     rep_origin      245773..245847
                     /note="ARS813;
                     Autonomously Replicating Sequence"
                     /db_xref="SGD:S000118359"
     gene            <246193..>248337
                     /gene="QNS1"
                     /locus_tag="YHR074W"
                     /db_xref="GeneID:856473"
     mRNA            <246193..>248337
                     /gene="QNS1"
                     /locus_tag="YHR074W"
                     /product="glutamine-dependent NAD(+) synthetase"
                     /transcript_id="NM_001179204.1"
                     /db_xref="GI:296145452"
                     /db_xref="GeneID:856473"
     CDS             246193..248337
                     /gene="QNS1"
                     /locus_tag="YHR074W"
                     /EC_number="6.3.5.1"
                     /note="Glutamine-dependent NAD(+) synthetase; essential
                     for the formation of NAD(+) from nicotinic acid adenine
                     dinucleotide"
                     /codon_start=1
                     /product="glutamine-dependent NAD(+) synthetase"
                     /protein_id="NP_011941.1"
                     /db_xref="GI:6321865"
                     /db_xref="SGD:S000001116"
                     /db_xref="GeneID:856473"
                     /translation="MSHLITLATCNLNQWALDFEGNRDRILQSIKIAKERGARLRVGP
                     ELEITGYGCLDHFLENDVCLHSWEMYAQIIKNKETHGLILDIGMPVLHKNVRYNCRLL
                     SLDGEILFIRPKIWLANDGNYREMRFFTPWMKPGVVEDFILPPEIQKVTGQRLVPFGD
                     AVINSLDTCIGTETCEELFTPQSPHIAMSLDGVEIMTNSSGSHHELRKLNKRLDLILN
                     ATKRCGGVYLYANQRGCDGDRLYYDGCALIAINGTIVAQGSQFSLDDVEVVTATVDLE
                     EVRSYRAAVMSRGLQASLAEIKFKRIDIPVELALMTSRFDPTVCPTKVREPFYHSPEE
                     EIALGPACWMWDYLRRCNGTGFFLPLSGGIDSCATAMIVHSMCRLVTDAAQNGNEQVI
                     KDVRKITRSGDDWIPDSPQDLASKIFHSCFMGTENSSKETRNRAKDLSNAIGSYHVDL
                     KMDSLVSSVVSLFEVATGKKPIYKIFGGSQIENLALQNIQARLRMVLSYLFAQLLPWV
                     RGIPNSGGLLVLGSANVDECLRGYLTKYDCSSADINPIGGISKTDLKRFIAYASKQYN
                     MPILNDFLNATPTAELEPMTKDYVQSDEIDMGMTYEELGVFGYLRKVEKCGPYSMFLK
                     LLHQWSPKLTPRQISEKVKRFFFFYAINRHKQTVLTPSYHAEQYSPEDNRFDLRPFLI
                     NPRFPWASRKIDEVVEQCEAHKGSTLDIMSID"
     gene            complement(<248439..>249641)
                     /gene="PPE1"
                     /locus_tag="YHR075C"
                     /db_xref="GeneID:856474"
     mRNA            complement(<248439..>249641)
                     /gene="PPE1"
                     /locus_tag="YHR075C"
                     /product="carboxylesterase-mitochondrial 37S ribosomal
                     protein YmS2"
                     /transcript_id="NM_001179205.1"
                     /db_xref="GI:296145453"
                     /db_xref="GeneID:856474"
     CDS             complement(248439..249641)
                     /gene="PPE1"
                     /locus_tag="YHR075C"
                     /EC_number="3.1.1.89"
                     /note="Protein with carboxyl methyl esterase activity; may
                     have a role in demethylation of the phosphoprotein
                     phosphatase catalytic subunit; also identified as a small
                     subunit mitochondrial ribosomal protein"
                     /codon_start=1
                     /product="carboxylesterase-mitochondrial 37S ribosomal
                     protein YmS2"
                     /protein_id="NP_011942.1"
                     /db_xref="GI:6321866"
                     /db_xref="SGD:S000001117"
                     /db_xref="GeneID:856474"
                     /translation="MSDDLRRKIALSQFERAKNVLDATFQEAYEDDENDGDALGSLPS
                     FNGQSNRNRKYTGKTGSTTDRISSKEKSSLPTWSDFFDNKELVSLPDRDLDVNTYYTL
                     PTSLLSNTTSIPIFIFHHGAGSSGLSFANLAKELNTKLEGRCGCFAFDARGHAETKFK
                     KADAPICFDRDSFIKDFVSLLNYWFKSKISQEPLQKVSVILIGHSLGGSICTFAYPKL
                     STELQKKILGITMLDIVEEAAIMALNKVEHFLQNTPNVFESINDAVDWHVQHALSRLR
                     SSAEIAIPALFAPLKSGKVVRITNLKTFSPFWDTWFTDLSHSFVGLPVSKLLILAGNE
                     NLDKELIVGQMQGKYQLVVFQDSGHFIQEDSPIKTAITLIDFWKRNDSRNVVIKTNWG
                     QHKTVQNT"
     gene            <251101..>252225
                     /gene="PTC7"
                     /locus_tag="YHR076W"
                     /db_xref="GeneID:856475"
     mRNA            join(<251101..251155,251249..>252225)
                     /gene="PTC7"
                     /locus_tag="YHR076W"
                     /product="type 2C protein phosphatase PTC7"
                     /transcript_id="NM_001179206.1"
                     /db_xref="GI:296145454"
                     /db_xref="GeneID:856475"
     CDS             join(251101..251155,251249..252225)
                     /gene="PTC7"
                     /locus_tag="YHR076W"
                     /EC_number="3.1.3.16"
                     /note="Type 2C serine/threonine protein phosphatase
                     (PP2C); alternatively spliced to create two mRNA isoforms;
                     protein from spliced form localizes to the mitochondria
                     while the one from the unspliced form is localized to the
                     nuclear envelope; activates coenzyme Q6 biosynthesis by
                     dephosphorylation of demethoxy-Q6 hydroxylase Coq7p"
                     /codon_start=1
                     /product="type 2C protein phosphatase PTC7"
                     /protein_id="NP_011943.2"
                     /db_xref="GI:154199605"
                     /db_xref="SGD:S000001118"
                     /db_xref="GeneID:856475"
                     /translation="MFANVGFRTLRVSRGPLYGSCSQIISFSKRTFYSSAKSGYQSNN
                     SHGDAYSSGSQSGPFTYKTAVAFQPKDRDDLIYQKLKDSIRSPTGEDNYFVTSNNVHD
                     IFAGVADGVGGWAEHGYDSSAISRELCKKMDEISTALAENSSKETLLTPKKIIGAAYA
                     KIRDEKVVKVGGTTAIVAHFPSNGKLEVANLGDSWCGVFRDSKLVFQTKFQTVGFNAP
                     YQLSIIPEEMLKEAERRGSKYILNTPRDADEYSFQLKKKDIIILATDGVTDNIATDDI
                     ELFLKDNAARTNDELQLLSQKFVDNVVSLSKDPNYPSVFAQEISKLTGKNYSGGKEDD
                     ITVVVVRVD"
     gene            complement(<252374..>255756)
                     /gene="NMD2"
                     /locus_tag="YHR077C"
                     /gene_synonym="IFS1; SUA1; SUP111; UPF2"
                     /db_xref="GeneID:856476"
     mRNA            complement(join(<252374..255637,255751..>255756))
                     /gene="NMD2"
                     /locus_tag="YHR077C"
                     /gene_synonym="IFS1; SUA1; SUP111; UPF2"
                     /product="Nmd2p"
                     /transcript_id="NM_001179207.1"
                     /db_xref="GI:296145455"
                     /db_xref="GeneID:856476"
     CDS             complement(join(252374..255637,255751..255756))
                     /gene="NMD2"
                     /locus_tag="YHR077C"
                     /gene_synonym="IFS1; SUA1; SUP111; UPF2"
                     /note="Protein involved in the nonsense-mediated mRNA
                     decay (NMD) pathway; interacts with Nam7p and Upf3p;
                     involved in telomere maintenance"
                     /codon_start=1
                     /product="Nmd2p"
                     /protein_id="NP_011944.2"
                     /db_xref="GI:6579193"
                     /db_xref="SGD:S000001119"
                     /db_xref="GeneID:856476"
                     /translation="MDDGRKKELHDLNTRAWNGEEVFPLKSKKLDSSIKRNTGFIKKL
                     KKGFVKGSESSLLKDLSEASLEKYLSEIIVTVTECLLNVLNKNDDVIAAVEIISGLHQ
                     RFNGRFTSPLLGAFLQAFENPSVDIESERDELQRITRVKGNLRVFTELYLVGVFRTLD
                     DIESKDAIPNFLQKKTGRKDPLLFSILREILNYKFKLGFTTTIATAFIKKFAPLFRDD
                     DNSWDDLIYDSKLKGALQSLFKNFIDATFARATELHKKVNKLQREHQKCQIRTGKLRD
                     EYVEEYDKLLPIFIRFKTSAITLGEFFKLEIPELEGASNDDLKETASPMITNQILPPN
                     QRLWENEDTRKFYEILPDISKTVEESQSSKTEKDSNVNSKNINLFFTDLEMADCKDII
                     DDLSNRYWSSYLDNKATRNRILKFFMETQDWSKLPVYSRFIATNSKYMPEIVSEFINY
                     LDNGFRSQLHSNKINVKNIIFFSEMIKFQLIPSFMIFHKIRTLIMYMQVPNNVEILTV
                     LLEHSGKFLLNKPEYKELMEKMVQLIKDKKNDRQLNMNMKSALENIITLLYPPSVKSL
                     NVTVKTITPEQQFYRILIRSELSSLDFKHIVKLVRKAHWDDVAIQKVLFSLFSKPHKI
                     SYQNIPLLTKVLGGLYSYRRDFVIRCIDQVLENIERGLEINDYGQNMHRISNVRYLTE
                     IFNFEMIKSDVLLDTIYHIIRFGHINNQPNPFYLNYSDPPDNYFRIQLVTTILLNINR
                     TPAAFTKKCKLLLRFFEYYTFIKEQPLPKETEFRVSSTFKKYENIFGNTKFERSENLV
                     ESASRLESLLKSLNAIKSKDDRVKGSSASIHNGKESAVPIESITEDDEDEDDENDDGV
                     DLLGEDEDAEISTPNTESAPGKHQAKQDESEDEDDEDDDEDDDDDDDDDDDDGEEGDE
                     DDDEDDDDEDDDDEEEEDSDSDLEYGGDLDADRDIEMKRMYEEYERKLKDEEERKAEE
                     ELERQFQKMMQESIDARKSEKVVASKIPVISKPVSVQKPLLLKKSEEPSSSKETYEEL
                     SKPKKIAFTFLTKSGKKTQSRILQLPTDVKFVSDVLEEEEKLKTERNKIKKIVLKRSF
                     D"
     gene            <256360..>258018
                     /locus_tag="YHR078W"
                     /db_xref="GeneID:856477"
     mRNA            <256360..>258018
                     /locus_tag="YHR078W"
                     /product="hypothetical protein"
                     /transcript_id="NM_001179208.1"
                     /db_xref="GI:296145456"
                     /db_xref="GeneID:856477"
     CDS             256360..258018
                     /locus_tag="YHR078W"
                     /note="High osmolarity-regulated gene of unknown function"
                     /codon_start=1
                     /product="hypothetical protein"
                     /protein_id="NP_011945.1"
                     /db_xref="GI:6321869"
                     /db_xref="SGD:S000001120"
                     /db_xref="GeneID:856477"
                     /translation="MEALIVFIVLSVSGAFAYKCSYERLWFKVGSLFDIISTSSKKNV
                     IPLASKMEVGSNEDVSSMGNFINKFYTEYSLPSHKVLQSLRVLFSLAMMTYTVTIEII
                     LWQIKVAGMDKEVTFITTWVWPLTAIMLSFILILFQPFFIIISLLNKFYNDKFDIDRL
                     IIVTCIILSTLIALLSYINIGPFQYTKNILTRLSIGGVTVMASLSGLATVSSLYYNFL
                     VIWHKFRNTPMSDPSFRNINNSNNNSKSLLWTTDAYIEEKIQDYEHNIEQNVQILRSL
                     EEEVGENSTFKAELMEKIAWYQLELGKLEALLQQSPQVRTFKKAFEVGFIIYCLHKLI
                     ITFLKRIPYIIYHSLKYPDDYDYENFSENAASDPLAITIANILDFSFFRFNYQHDLDS
                     LTKQISLFLSISLFLCCLSAVNTTISYVVTLLPIKFQILALFAMQNDDTANVLPEYTN
                     NSSYKGKKRNYSQEQKGISLIKNLVVSELTGVYVLATTLMVRSHLPFEVSQRLKELLG
                     GKFTVPNIVIDSWFDEVYAFACVFTFICIRIAERKLSTKKVSVE"
     gene            complement(<258244..>261591)
                     /gene="IRE1"
                     /locus_tag="YHR079C"
                     /gene_synonym="ERN1"
                     /db_xref="GeneID:856478"
     mRNA            complement(<258244..>261591)
                     /gene="IRE1"
                     /locus_tag="YHR079C"
                     /gene_synonym="ERN1"
                     /product="bifunctional endoribonuclease/protein kinase
                     IRE1"
                     /transcript_id="NM_001179209.1"
                     /db_xref="GI:296145457"
                     /db_xref="GeneID:856478"
     CDS             complement(258244..261591)
                     /gene="IRE1"
                     /locus_tag="YHR079C"
                     /gene_synonym="ERN1"
                     /EC_number="3.1.26.-"
                     /EC_number="2.7.11.1"
                     /note="Serine-threonine kinase and endoribonuclease;
                     transmembrane protein that mediates the unfolded protein
                     response (UPR) by regulating Hac1p synthesis through HAC1
                     mRNA splicing; role in homeostatic adaptation to ER
                     stress; Kar2p binds inactive Ire1p and releases from it
                     upon ER stress"
                     /codon_start=1
                     /product="bifunctional endoribonuclease/protein kinase
                     IRE1"
                     /protein_id="NP_011946.1"
                     /db_xref="GI:6321870"
                     /db_xref="SGD:S000001121"
                     /db_xref="GeneID:856478"
                     /translation="MRLLRRNMLVLTLLVCVFSSIISCSIPLSSRTSRRQIVEDEVAS
                     TKKLNFNYGVDKNINSPIPAPRTTEGLPNMKLSSYPTPNLLNTADNRRANKKGRRAAN
                     SISVPYLENRSLNELSLSDILIAADVEGGLHAVDRRNGHIIWSIEPENFQPLIEIQEP
                     SRLETYETLIIEPFGDGNIYYFNAHQGLQKLPLSIRQLVSTSPLHLKTNIVVNDSGKI
                     VEDEKVYTGSMRTIMYTINMLNGEIISAFGPGSKNGYFGSQSVDCSPEEKIKLQECEN
                     MIVIGKTIFELGIHSYDGASYNVTYSTWQQNVLDVPLALQNTFSKDGMCIAPFRDKSL
                     LASDLDFRIARWVSPTFPGIIVGLFDVFNDLRTNENILVPHPFNPGDHESISSNKVYL
                     DQTSNLSWFALSSQNFPSLVESAPISRYASSDRWRVSSIFEDETLFKNAIMGVHQIYN
                     NEYDHLYENYEKTNSLDTTHKYPPLMIDSSVDTTDLHQNNEMNSLKEYMSPEDLEAYR
                     KKIHEQISRELDEKNQNSLLLKFGSLVYRIIETGVFLLLFLIFCAILQRFKILPPLYV
                     LLSKIGFMPEKEIPIVESKSLNCPSSSENVTKPFDMKSGKQVVFEGAVNDGSLKSEKD
                     NDDADEDDEKSLDLTTEKKKRKRGSRGGKKGRKSRIANIPNFEQSLKNLVVSEKILGY
                     GSSGTVVFQGSFQGRPVAVKRMLIDFCDIALMEIKLLTESDDHPNVIRYYCSETTDRF
                     LYIALELCNLNLQDLVESKNVSDENLKLQKEYNPISLLRQIASGVAHLHSLKIIHRDL
                     KPQNILVSTSSRFTADQQTGAENLRILISDFGLCKKLDSGQSSFRTNLNNPSGTSGWR
                     APELLEESNNLQCQVETEHSSSRHTVVSSDSFYDPFTKRRLTRSIDIFSMGCVFYYIL
                     SKGKHPFGDKYSRESNIIRGIFSLDEMKCLHDRSLIAEATDLISQMIDHDPLKRPTAM
                     KVLRHPLFWPKSKKLEFLLKVSDRLEIENRDPPSALLMKFDAGSDFVIPSGDWTVKFD
                     KTFMDNLERYRKYHSSKLMDLLRALRNKYHHFMDLPEDIAELMGPVPDGFYDYFTKRF
                     PNLLIGVYMIVKENLSDDQILREFLYS"
     gene            complement(<262192..>262553)
                     /gene="SAE3"
                     /locus_tag="YHR079C-A"
                     /gene_synonym="YHR079C-B"
                     /db_xref="GeneID:856479"
     mRNA            complement(join(<262192..262354,262441..>262553))
                     /gene="SAE3"
                     /locus_tag="YHR079C-A"
                     /gene_synonym="YHR079C-B"
                     /product="Sae3p"
                     /transcript_id="NM_001180026.1"
                     /db_xref="GI:296145458"
                     /db_xref="GeneID:856479"
     CDS             complement(join(262192..262354,262441..262553))
                     /gene="SAE3"
                     /locus_tag="YHR079C-A"
                     /gene_synonym="YHR079C-B"
                     /note="Meiosis-specific protein involved in meiotic
                     recombination; involved in DMC1-dependent meiotic
                     recombination; forms heterodimer with Mei5p; proposed to
                     be an assembly factor for Dmc1p"
                     /codon_start=1
                     /product="Sae3p"
                     /protein_id="NP_011947.2"
                     /db_xref="GI:81357323"
                     /db_xref="SGD:S000001957"
                     /db_xref="GeneID:856479"
                     /translation="MNYLETQLNKKQKQIQEYESMNGNLIKMFEQLSKEKKNDETPKK
                     ISSTYIKELKEYNELRDAGLRLAQIIADEKQCKIKDVFEEIGYSMKD"
     gene            complement(<262801..>266838)
                     /locus_tag="YHR080C"
                     /db_xref="GeneID:856480"
     mRNA            complement(<262801..>266838)
                     /locus_tag="YHR080C"
                     /product="hypothetical protein"
                     /transcript_id="NM_001179210.1"
                     /db_xref="GI:296145459"
                     /db_xref="GeneID:856480"
     CDS             complement(262801..266838)
                     /locus_tag="YHR080C"
                     /note="hypothetical protein; may interact with ribosomes,
                     based on co-purification experiments; the authentic,
                     non-tagged protein is detected in highly purified
                     mitochondria in high-throughput studies; YHR080C has a
                     paralog, YSP2, that arose from the whole genome
                     duplication"
                     /codon_start=1
                     /product="hypothetical protein"
                     /protein_id="NP_011948.1"
                     /db_xref="GI:6321872"
                     /db_xref="SGD:S000001122"
                     /db_xref="GeneID:856480"
                     /translation="MTRDSKKKHHWGTAFLRTIGVKRKHKKDRNFLNNTTGENVSTTA
                     SAERFRRVGGNPDIPSLLKPETFTESPAKGSQKAAASSLAHSQGVFNIPIVIDPMETN
                     RLEKTNTNLTAGSLKGRFQDGNSNSNSVPSLSVQALEKEKLQSGKREGSSNQAEEKTP
                     DGHDEHTAFETFLSFAHNAVSHIPKINVQDADNGTISRNEPKDRKKNSSNISGALSEN
                     STNNKNTSSTKESDGPFLKNLDNILAASKSSTPSNQQLNTTEAGSKSKPSSLSRLAFG
                     NLKGHIHSNSHSSSNAISGDDTSLDDTRKMTDDMARKVVFEPIRHSHDKPTPGVGNLK
                     LEHFDDSQATLEGLEAMSAESLPEADHLDSRGPVQQSNLERKTVPSKWSVVSSSTTDG
                     VKPRRRAKSMISAMADKQNTSSDVLQDCKKRLSFNSSNGLTNNDPEYEDREPREMSKK
                     FLNRRSFSPGSISMGMKVLPSTALKYSLNKVKNSTDIASTIIPRPSMSNGRPSSGLRR
                     SSSKSFSSTPVNIIEPSEENGRQSSIRIKGVEYASEKKDAEFHAIFKDSGVSPNERLI
                     LDHSCALSRDILLQGRMYISDQHIGFYSNILGWVSTVFIPFKTIVQIEKRATAGIFPN
                     GIVIDTLHTKYTFASFTSRDATYDLITEVWNQIILGKRFRSNSNNTNSSSNSISDDEN
                     DDYDDDYDDYGDDDDDLYDNSNNISDSTDMTSSVSIGKPEDLPMPLQTDTPYGTGIPP
                     LGPKIHSPTETVYKPAPNEKLVNESTIHASLGRVVNILFGKDVSYIMAILKAQKNSDI
                     SPIPVLVDSPTVSEGKKRDYSYVKTTPGAIGPGKTKCMITETIQHFNLEEYVQVLQTT
                     KTPDVPSGNSFYVRTVYLLSWANNNETKLKLYVSVEWTGKSLIKSPIEKGTFDGVTDA
                     TKILVEELGNILTRSATKRKRSSKENTVTVSTLPKMEPSSHAPTEPDIQKDKDDSIIR
                     ENENIPAPLGTVVQLLFGSNTEYMQKVITRDKNNVNVETIPKFTPSLVEGGSRHYEYT
                     KKLNNSIGPKQTKCLLTESIEHMDINNYVLVTQTTKTPDVPSGSNFAVESKIFLFWGQ
                     HDTTNMTVITKINWTSKSFLKGAIEKGSVEGQKVSVDYMLSELRDIISRAKSKKPVKK
                     VMKSHDKHRPFHSKVEQKSSESRKSDDNKDILTHILDFVQNNFSSEIFMNKLLSPQKL
                     FLILGLTIMLFWSPRLHVFQEKNNLQIIKPGRLLIDGQEYNYVPSFGTLYNSYENAIS
                     SKKKRENVNYARDKSPIVGRESDIWDWISNRGSAISPRGRAMLRNDDEHKLQQLSESI
                     KITEMQLNHMKTMLDNIERDANDLS"
     gene            <267538..>268092
                     /gene="LRP1"
                     /locus_tag="YHR081W"
                     /gene_synonym="RRP47"
                     /db_xref="GeneID:856481"
     mRNA            <267538..>268092
                     /gene="LRP1"
                     /locus_tag="YHR081W"
                     /gene_synonym="RRP47"
                     /product="Lrp1p"
                     /transcript_id="NM_001179211.1"
                     /db_xref="GI:296145460"
                     /db_xref="GeneID:856481"
     CDS             267538..268092
                     /gene="LRP1"
                     /locus_tag="YHR081W"
                     /gene_synonym="RRP47"
                     /note="Nuclear exosome-associated nucleic acid binding
                     protein; involved in RNA processing, surveillance,
                     degradation, tethering, and export; forms a stable
                     heterodimer with Rrp6p and regulates its exonucleolytic
                     activity; rapidly degraded by the proteasome in the
                     absence of Rrp6p; homolog of mammalian nuclear matrix
                     protein C1D involved in regulation of DNA repair and
                     recombination"
                     /codon_start=1
                     /product="Lrp1p"
                     /protein_id="NP_011949.1"
                     /db_xref="GI:6321873"
                     /db_xref="SGD:S000001123"
                     /db_xref="GeneID:856481"
                     /translation="MEDIEKIKPYVRSFSKALDELKPEIEKLTSKSLDEQLLLLSDER
                     AKLELINRYAYVLSSLMFANMKVLGVKDMSPILGELKRVKSYMDKAKQYDNRITKSNE
                     KSQAEQEKAKNIISNVLDGNKNQFEPSISRSNFQGKHTKFENDELAESTTTKIIDSTD
                     HIRKASSKKSKRLDKVGKKKGGKK"
     gene            complement(<268459..>271548)
                     /gene="KSP1"
                     /locus_tag="YHR082C"
                     /db_xref="GeneID:856482"
     mRNA            complement(<268459..>271548)
                     /gene="KSP1"
                     /locus_tag="YHR082C"
                     /product="putative serine/threonine protein kinase KSP1"
                     /transcript_id="NM_001179212.1"
                     /db_xref="GI:296145461"
                     /db_xref="GeneID:856482"
     CDS             complement(268459..271548)
                     /gene="KSP1"
                     /locus_tag="YHR082C"
                     /EC_number="2.7.11.1"
                     /note="Serine/threonine protein kinase; associates with
                     TORC1 and likely involved in TOR signaling cascades;
                     negative regulator of autophagy; nuclear translocation
                     required for haploid filamentous growth; regulates
                     filamentous growth induced nuclear translocation of Bcy1p,
                     Fus3p, and Sks1p; overproduction causes allele-specific
                     suppression of prp20-10; protein abundance increases in
                     response to DNA replication stress"
                     /codon_start=1
                     /product="putative serine/threonine protein kinase KSP1"
                     /protein_id="NP_011950.1"
                     /db_xref="GI:6321874"
                     /db_xref="SGD:S000001124"
                     /db_xref="GeneID:856482"
                     /translation="MTLDYEIYKEGGILNNRYQKIEDISEGSYGYVSLAKDVREKRLV
                     AVKYIFKLEDDGQYDGPQDDENDCDSSDCDDDEDTKVDTDRHENENGNASSNNGSSRE
                     KKHNLYKHKKSLISSKVKSRLSNNICLEAMYEVDIQTKIGRHQNIAALLDFFDSYIIM
                     EYCSGGDLYEAIKADAVPKKTKSITHIITQIMDAIEYVHNKGIYHRDIKPENILISGI
                     DWTIKLTDWGLATTDKTSMDRNVGSERYMSPELFDSNLDIKERKEPYDCAKVDLWAMG
                     IVFLNIVFHKNPFSIANQSDKSFCYFAANREALFDVFSTMAYDFFQVLRYSLTIDPAN
                     RDLKMMRTELQNLSEYTLDDEYYNNLDEGYEETMIDGLPPQPVPPSSAPVSLPTPISS
                     SNKQHMPEFKKDFNFNNVNERKRSDVSQNQNVASGFFKKPSTQQQKFFNQGYNTTLST
                     HERAKSAPKFKFKKRNKYGRTDNQFSKPVNIEDRKKSKILKKSRKPLGIPTPNTHMNN
                     FFHDYKARDEFNTRDFFTPPSVQHRYMEGFSNNNNKQYRQNRNYNNNNNNSNNNHGSN
                     YNNFNNGNSYIKGWNKNFNKYRRPSSSSYTGKSPLSRYNMSYNHNNNSSINGYARRGS
                     TTTVQHSPGAYIPPNARNHHVSPTNQFLRVPQSTAPDISTVLGGKPSYQEHYTQDSMD
                     SEGDHDSDDVLFTLEEGDHDFVNGMDNLSINDHLPHTTVGSHNEVFVHASTNHNNNGN
                     NNHIDTNSTTNQYHRQYIPPPLTTSLHINNNNNESNELPDLLKSPASSEAHLNLSSGP
                     IDPILTGNIGNRYSHSSDSKELEQERRLSMEQKFKNGVYVPPHHRKSFNLGTQVPPMN
                     MKTSNEATLSVSHNSVNFGGSYNSRRSSANESNPLHMNKALEKLSSSPGAKSSFVGFP
                     KPLLPRNHSSTTIALQNEDVFADSNNDAIIFEDEEYEGESDKMAHGKMEGGDNESSST
                     SPDERQIFGPYEIYAQTFAGSTHDKKLGAGRKTSIQDEMVGSLEQYKNNWLILQQQD"
     gene            <272627..>273616
                     /gene="SAM35"
                     /locus_tag="YHR083W"
                     /gene_synonym="FMP20; TOB38; TOM38"
                     /db_xref="GeneID:856483"
     mRNA            <272627..>273616
                     /gene="SAM35"
                     /locus_tag="YHR083W"
                     /gene_synonym="FMP20; TOB38; TOM38"
                     /product="SAM complex subunit SAM35"
                     /transcript_id="NM_001179213.1"
                     /db_xref="GI:296145462"
                     /db_xref="GeneID:856483"
     CDS             272627..273616
                     /gene="SAM35"
                     /locus_tag="YHR083W"
                     /gene_synonym="FMP20; TOB38; TOM38"
                     /note="Component of the sorting and assembly machinery
                     (SAM) complex; the SAM (or TOB) complex is located in the
                     mitochondrial outer membrane; the complex binds precursors
                     of beta-barrel proteins and facilitates their insertion
                     into the outer membrane"
                     /codon_start=1
                     /product="SAM complex subunit SAM35"
                     /protein_id="NP_011951.1"
                     /db_xref="GI:6321875"
                     /db_xref="SGD:S000001125"
                     /db_xref="GeneID:856483"
                     /translation="MVSSFSVPMPVKRIFDTFPLQTYAAQTDKDEAVALEIQRRSYTF
                     TERGGGSSELTVEGTYKLGVYNVFLEANTGAALATDPWCLFVQLALCQKNGLVLPTHS
                     QEQTPSHTCNHEMLVLSRLSNPDEALPILVEGYKKRIIRSTVAISEIMRSRILDDAEQ
                     LMYYTLLDTVLYDCWITQIIFCASDAQFMELYSCQKLSGSIVTPLDVENSLLQKLSAK
                     SLKISLTKRNKFQFRHREIVKSMQGVYHNHHNSVNQEQVLNVLFENSKQVLLGLKDML
                     KSDGQPTYLHLKIASYILCITNVKEPIKLKTFVENECKELVQFAQDTLKNFVQ"
     gene            <274174..>276240
                     /gene="STE12"
                     /locus_tag="YHR084W"
                     /db_xref="GeneID:856484"
     mRNA            <274174..>276240
                     /gene="STE12"
                     /locus_tag="YHR084W"
                     /product="homeodomain family transcription factor STE12"
                     /transcript_id="NM_001179214.1"
                     /db_xref="GI:296145463"
                     /db_xref="GeneID:856484"
     CDS             274174..276240
                     /gene="STE12"
                     /locus_tag="YHR084W"
                     /note="Transcription factor that is activated by a MAPK
                     signaling cascade; activates genes involved in mating or
                     pseudohyphal/invasive growth pathways; cooperates with
                     Tec1p transcription factor to regulate genes specific for
                     invasive growth"
                     /codon_start=1
                     /product="homeodomain family transcription factor STE12"
                     /protein_id="NP_011952.1"
                     /db_xref="GI:6321876"
                     /db_xref="SGD:S000001126"
                     /db_xref="GeneID:856484"
                     /translation="MKVQITNSRTEEILKVQANNENDEVSKATPGEVEESLRLIGDLK
                     FFLATAPVNWQENQIIRRYYLNSGQGFVSCVFWNNLYYITGTDIVKCCLYRMQKFGRE
                     VVQKKKFEEGIFSDLRNLKCGIDATLEQPKSEFLSFLFRNMCLKTQKKQKVFFWFSVA
                     HDKLFADALERDLKRESLNQPSTTKPVNEPALSFSYDSSSDKPLYDQLLQHLDSRRPS
                     STTKSDNSPPKLESENFKDNELVTVTNQPLLGVGLMDDDAPESPSQINDFIPQKLIIE
                     PNTLELNGLTEETPHDLPKNTAKGRDEEDFPLDYFPVSVEYPTEENAFDPFPPQAFTP
                     AAPSMPISYDNVNERDSMPVNSLLNRYPYQLSVAPTFPVPPSSSRQHFMTNRDFYSSN
                     NNKEKLVSPSDPTSYMKYDEPVMDFDESRPNENCTNAKSHNSGQQTKQHQLYSNNFQQ
                     SYPNGMVPGYYPKMPYNPMGGDPLLDQAFYGADDFFFPPEGCDNNMLYPQTATSWNVL
                     PPQAMQPAPTYVGRPYTPNYRSTPGSAMFPYMQSSNSMQWNTAVSPYSSRAPSTTAKN
                     YPPSTFYSQNINQYPRRRTVGMKSSQGNVPTGNKQSVGKSAKISKPLHIKTSAYQKQY
                     KINLETKARPSAGDEDSAHPDKNKEISMPTPDSNTLVVQSEEGGAHSLEVDTNRRSDK
                     NLPDAT"
     gene            <276764..>277768
                     /gene="IPI1"
                     /locus_tag="YHR085W"
                     /db_xref="GeneID:856485"
     mRNA            <276764..>277768
                     /gene="IPI1"
                     /locus_tag="YHR085W"
                     /product="Ipi1p"
                     /transcript_id="NM_001179215.1"
                     /db_xref="GI:296145464"
                     /db_xref="GeneID:856485"
     CDS             276764..277768
                     /gene="IPI1"
                     /locus_tag="YHR085W"
                     /note="Component of the Rix1 complex and possibly
                     pre-replicative complexes; required for processing of ITS2
                     sequences from 35S pre-rRNA; component of the pre-60S
                     ribosomal particle with the dynein-related AAA-type ATPase
                     Mdn1p; required for pre-replicative complex (pre-RC)
                     formation and maintenance during DNA replication
                     licensing; relocalizes to the cytosol in response to
                     hypoxia; essential gene"
                     /codon_start=1
                     /product="Ipi1p"
                     /protein_id="NP_011953.1"
                     /db_xref="GI:6321877"
                     /db_xref="SGD:S000001127"
                     /db_xref="GeneID:856485"
                     /translation="MTKSRKQKQKKQDFLRKKLKVGKPKEKARNATDTSFVSKTISIR
                     NQHLDQNPHDLTKRLTLLKHHNINVRKETLTTFQKSIPSIIKSRLMTPLLTQSIPLIC
                     DESQQVRQGLIDLVDEIGSHDAEILKLHCNIFVLYINMAMTHIVTQIQADSTKFLSHL
                     LKYCGDEVVRKSWVKLLNGVFGVLGWGQVGKNDSASIVQTKKRNAKYVTIHLNALYTL
                     VEYGCQDERARSDGDTAETTEDSGTLRNPYLIPDYPQPFEHLKLFTRELKVQDATSSG
                     VNATLLSLATQDIDTRKAVFIEQFLPIVRKKIEVIIKEGGECGKSANKLKTLLAKIFD
                     "
     gene            <278153..>279724
                     /gene="NAM8"
                     /locus_tag="YHR086W"
                     /gene_synonym="MRE2; MUD15"
                     /db_xref="GeneID:856486"
     mRNA            <278153..>279724
                     /gene="NAM8"
                     /locus_tag="YHR086W"
                     /gene_synonym="MRE2; MUD15"
                     /product="Nam8p"
                     /transcript_id="NM_001179216.1"
                     /db_xref="GI:296145465"
                     /db_xref="GeneID:856486"
     CDS             278153..279724
                     /gene="NAM8"
                     /locus_tag="YHR086W"
                     /gene_synonym="MRE2; MUD15"
                     /note="RNA binding protein, component of the U1 snRNP
                     protein; mutants are defective in meiotic recombination
                     and in formation of viable spores, involved in the
                     formation of DSBs through meiosis-specific splicing of
                     REC107 pre-mRNA; Nam8p regulon embraces the meiotic
                     pre-mRNAs of REC107, HFM1, AMA1 SPO22 and PCH2; the
                     putative RNA binding domains RRM2 and RRM3 are required
                     for Nam8p meiotic function"
                     /codon_start=1
                     /product="Nam8p"
                     /protein_id="NP_011954.1"
                     /db_xref="GI:6321878"
                     /db_xref="SGD:S000001128"
                     /db_xref="GeneID:856486"
                     /translation="MSYKQTTYYPSRGNLVRNDSSPYTNTISSETNNSSTSVLSLQGA
                     SNVSLGTTGNQLYMGDLDPTWDKNTVRQIWASLGEANINVRMMWNNTLNNGSRSSMGP
                     KNNQGYCFVDFPSSTHAANALLKNGMLIPNFPNKKLKLNWATSSYSNSNNSLNNVKSG
                     NNCSIFVGDLAPNVTESQLFELFINRYASTSHAKIVHDQVTGMSKGYGFVKFTNSDEQ
                     QLALSEMQGVFLNGRAIKVGPTSGQQQHVSGNNDYNRSSSSLNNENVDSRFLSKGQSF
                     LSNGNNNMGFKRNHMSQFIYPVQQQPSLNHFTDPNNTTVFIGGLSSLVTEDELRAYFQ
                     PFGTIVYVKIPVGKCCGFVQYVDRLSAEAAIAGMQGFPIANSRVRLSWGRSAKQTALL
                     QQAMLSNSLQVQQQQPGLQQPNYGYIPSSTCEAPVLPDNNVSSTMLPGCQILNYSNPY
                     ANANGLGSNNFSFYSNNNATNTQATSLLADTSSMDLSGTGGQQVIMQGSEAVVNSTNA
                     MLNRLEQGSNGFMFA"
     gene            <280231..>280392
                     /locus_tag="YHR086W-A"
                     /db_xref="GeneID:1466529"
     mRNA            <280231..>280392
                     /locus_tag="YHR086W-A"
                     /product="hypothetical protein"
                     /transcript_id="NM_001184553.1"
                     /db_xref="GI:296145466"
                     /db_xref="GeneID:1466529"
     CDS             280231..280392
                     /locus_tag="YHR086W-A"
                     /note="hypothetical protein; identified by fungal homology
                     and RT-PCR"
                     /codon_start=1
                     /product="hypothetical protein"
                     /protein_id="NP_878089.1"
                     /db_xref="GI:33438807"
                     /db_xref="SGD:S000028552"
                     /db_xref="GeneID:1466529"
                     /translation="MRLSLYSCCLCIGARRIPTPCLFSYIFTPNLAHFHSPLRSSGFR
                     PAGATRFYS"
     gene            <280820..>281155
                     /gene="RTC3"
                     /locus_tag="YHR087W"
                     /gene_synonym="HGI1"
                     /db_xref="GeneID:856487"
     mRNA            <280820..>281155
                     /gene="RTC3"
                     /locus_tag="YHR087W"
                     /gene_synonym="HGI1"
                     /product="Rtc3p"
                     /transcript_id="NM_001179217.1"
                     /db_xref="GI:296145467"
                     /db_xref="GeneID:856487"
     CDS             280820..281155
                     /gene="RTC3"
                     /locus_tag="YHR087W"
                     /gene_synonym="HGI1"
                     /note="hypothetical protein involved in RNA metabolism;
                     has structural similarity to SBDS, the human protein
                     mutated in Shwachman-Diamond Syndrome (the yeast SBDS
                     ortholog = SDO1); null mutation suppresses cdc13-1
                     temperature sensitivity; protein abundance increases in
                     response to DNA replication stress"
                     /codon_start=1
                     /product="Rtc3p"
                     /protein_id="NP_011955.1"
                     /db_xref="GI:6321879"
                     /db_xref="SGD:S000001129"
                     /db_xref="GeneID:856487"
                     /translation="MSTVTKYFYKGENTDLIVFAASEELVDEYLKNPSIGKLSEVVEL
                     FEVFTPQDGRGAEGELGAASKAQVENEFGKGKKIEEVIDLILRNGKPNSTTSSLKTKG
                     GNAGTKAYN"
     gene            <281495..>282382
                     /gene="RPF1"
                     /locus_tag="YHR088W"
                     /db_xref="GeneID:856488"
     mRNA            <281495..>282382
                     /gene="RPF1"
                     /locus_tag="YHR088W"
                     /product="Rpf1p"
                     /transcript_id="NM_001179218.1"
                     /db_xref="GI:296145468"
                     /db_xref="GeneID:856488"
     CDS             281495..282382
                     /gene="RPF1"
                     /locus_tag="YHR088W"
                     /note="Protein involved in assembly and export of the
                     large ribosomal subunit; nucleolar protein; constituent of
                     66S pre-ribosomal particles; contains a sigma(70)-like
                     motif, which is thought to bind RNA"
                     /codon_start=1
                     /product="Rpf1p"
                     /protein_id="NP_011956.1"
                     /db_xref="GI:6321880"
                     /db_xref="SGD:S000001130"
                     /db_xref="GeneID:856488"
                     /translation="MALGNEINITNKLKRQEIFADIKHEKNKERHTMRRKRAKEEREN
                     PELREQRLKENVTQTIENTRVYDETINKEVEGDEDDLMRYFNSNSNEPPKIFLTTNVN
                     AKKSAYEFANILIEILPNVTFVKRKFGYKLKEISDICIKRNFTDIVIINEDKKKVTGL
                     TFIHLPEGPTFYFKLSSFVEVKKIVGHGRPTSHIPELILNNFQTRLGQTVGRLFQSIL
                     PQNPDIEGRQVITLHNQRDYIFFRRHRYVFKDNERVGLQELGPQFTLKLKRLQRGIKE
                     ETEWEHKPEMDKEKKKFYL"
     gene            complement(<282681..>283298)
                     /gene="GAR1"
                     /locus_tag="YHR089C"
                     /db_xref="GeneID:856489"
     mRNA            complement(<282681..>283298)
                     /gene="GAR1"
                     /locus_tag="YHR089C"
                     /product="H/ACA snoRNP pseudouridylase subunit GAR1"
                     /transcript_id="NM_001179219.1"
                     /db_xref="GI:296145469"
                     /db_xref="GeneID:856489"
     CDS             complement(282681..283298)
                     /gene="GAR1"
                     /locus_tag="YHR089C"
                     /note="Protein component of the H/ACA snoRNP
                     pseudouridylase complex; involved in the modification and
                     cleavage of the 18S pre-rRNA"
                     /codon_start=1
                     /product="H/ACA snoRNP pseudouridylase subunit GAR1"
                     /protein_id="NP_011957.1"
                     /db_xref="GI:6321881"
                     /db_xref="SGD:S000001131"
                     /db_xref="GeneID:856489"
                     /translation="MSFRGGNRGGRGGFRGGFRGGRTGSARSFQQGPPDTVLEMGAFL
                     HPCEGDIVCRSINTKIPYFNAPIYLENKTQVGKVDEILGPLNEVFFTIKCGDGVQATS
                     FKEGDKFYIAADKLLPIERFLPKPKVVGPPKPKNKKKRSGAPGGRGGASMGRGGSRGG
                     FRGGRGGSSFRGGRGGSSFRGGSRGGSFRGGSRGGSRGGFRGGRR"
     gene            complement(<283777..>284625)
                     /gene="YNG2"
                     /locus_tag="YHR090C"
                     /gene_synonym="EAF4; NBN1"
                     /db_xref="GeneID:856490"
     mRNA            complement(<283777..>284625)
                     /gene="YNG2"
                     /locus_tag="YHR090C"
                     /gene_synonym="EAF4; NBN1"
                     /product="histone acetyltransferase YNG2"
                     /transcript_id="NM_001179220.1"
                     /db_xref="GI:296145470"
                     /db_xref="GeneID:856490"
     CDS             complement(283777..284625)
                     /gene="YNG2"
                     /locus_tag="YHR090C"
                     /gene_synonym="EAF4; NBN1"
                     /note="Subunit of NuA4, an essential histone
                     acetyltransferase complex; positions Piccolo NuA4 for
                     efficient acetylation of histone H4 or histone H2A;
                     relocalizes to the cytosol in response to hypoxia; similar
                     to human tumor suppressor ING1 and its isoforms ING4 and
                     ING5"
                     /codon_start=1
                     /product="histone acetyltransferase YNG2"
                     /protein_id="NP_011958.1"
                     /db_xref="GI:6321882"
                     /db_xref="SGD:S000001132"
                     /db_xref="GeneID:856490"
                     /translation="MDPSLVLEQTIQDVSNLPSEFRYLLEEIGSNDLKLIEEKKKYEQ
                     KESQIHKFIRQQGSIPKHPQEDGLDKEIKESLLKCQSLQREKCVLANTALFLIARHLN
                     KLEKNIALLEEDGVLAPVEEDGDMDSAAEASRESSVVSNSSVKKRRAASSSGSVPPTL
                     KKKKTSRTSKLQNEIDVSSREKSVTPVSPSIEKKIARTKEFKNSRNGKGQNGSPENEE
                     EDKTLYCFCQRVSFGEMVACDGPNCKYEWFHYDCVNLKEPPKGTWYCPECKIEMEKNK
                     LKRKRN"
     gene            complement(<284839..>286770)
                     /gene="MSR1"
                     /locus_tag="YHR091C"
                     /db_xref="GeneID:856491"
     mRNA            complement(<284839..>286770)
                     /gene="MSR1"
                     /locus_tag="YHR091C"
                     /product="arginine--tRNA ligase MSR1"
                     /transcript_id="NM_001179221.1"
                     /db_xref="GI:296145471"
                     /db_xref="GeneID:856491"
     CDS             complement(284839..286770)
                     /gene="MSR1"
                     /locus_tag="YHR091C"
                     /EC_number="6.1.1.19"
                     /note="Mitochondrial arginyl-tRNA synthetase; mutations in
                     human ortholog are associated with pontocerebellar
                     hypoplasia type 6; MSR1 has a paralog, YDR341C, that arose
                     from the whole genome duplication"
                     /codon_start=1
                     /product="arginine--tRNA ligase MSR1"
                     /protein_id="NP_011959.1"
                     /db_xref="GI:6321883"
                     /db_xref="SGD:S000001133"
                     /db_xref="GeneID:856491"
                     /translation="MFGIVYLKNRSLLCKNPFSSYPRYGFMPSFDTQFSNQFRKLEIN
                     IGRKRYSSKTLNTKYTDQPEGPIYPLDVLRLDISKALHDISGIDHSLILNALESTNSM
                     DRGDLLLPLPKIKVADPVAVANRWAIELSTHGCIGKVCAKGPFLQFFLDQRYLIQSTV
                     PNILLQKGKYGQKKSRHQKKVVVEFSSPNIAKPFHAGHLRSTIIGGFLSNLYEAMGWS
                     VTRMNYLGDWGRQFGLLAVGFKRYGDEKTLQKQPIQHLFDVYVKINMDLAKEEINGNS
                     KCGISGEARSFFKNLENGDENAIKIWNRFRSLSIHHYIQTYSRLNINFDIFSGESQVS
                     KESMNEALDIFRKNNLVKEIDGALVIDLTQWSKRLGRVVVQKSDGTTLYLTRDVGAAI
                     ERKKNLHFDKMVYVISSQQDLYMSQFFMILKKMNFEWAKDLQHINFGMVQGMSTRKGN
                     VVFLDTILDEARDKALQIMENNKMKISQVDNPQRVADLIGVSAIIIQDMKSKRINNYE
                     FNWNRMLSFEGDTGPYLQYTHSRLRSLERTSSDFTTDMLIHADFSNLNEPQLVELVRL
                     LAQYPDVLRRAFETQEPATIVTYLFKVCHQVSSCYKKIWVSGKPADIAIPRLAVYSAS
                     RQVLHNAMSLLGLVPVDRM"
     rep_origin      286770..287128
                     /note="ARS814;
                     Putative replication origin; identified in multiple array
                     studies, not yet confirmed by plasmid-based assay"
                     /db_xref="SGD:S000130149"
     gene            complement(<287081..>288811)
                     /gene="HXT4"
                     /locus_tag="YHR092C"
                     /gene_synonym="LGT1; RAG1"
                     /db_xref="GeneID:856492"
     mRNA            complement(<287081..>288811)
                     /gene="HXT4"
                     /locus_tag="YHR092C"
                     /gene_synonym="LGT1; RAG1"
                     /product="hexose transporter HXT4"
                     /transcript_id="NM_001179222.2"
                     /db_xref="GI:330443584"
                     /db_xref="GeneID:856492"
     CDS             complement(287081..288811)
                     /gene="HXT4"
                     /locus_tag="YHR092C"
                     /gene_synonym="LGT1; RAG1"
                     /note="High-affinity glucose transporter; member of the
                     major facilitator superfamily, expression is induced by
                     low levels of glucose and repressed by high levels of
                     glucose; HXT4 has a paralog, HXT7, that arose from the
                     whole genome duplication"
                     /codon_start=1
                     /product="hexose transporter HXT4"
                     /protein_id="NP_011960.2"
                     /db_xref="GI:330443585"
                     /db_xref="SGD:S000001134"
                     /db_xref="GeneID:856492"
                     /translation="MSEEAAYQEDTAVQNTPADALSPVESDSNSALSTPSNKAERDDM
                     KDFDENHEESNNYVEIPKKPASAYVTVSICCLMVAFGGFVFGWDTGTISGFVAQTDFI
                     RRFGMKHHDGTYYLSKVRTGLIVSIFNIGCAIGGIILAKLGDMYGRKMGLIVVVVIYI
                     IGIIIQIASINKWYQYFIGRIISGLGVGGIAVLSPMLISEVSPKHIRGTLVSCYQLMI
                     TLGIFLGYCTNYGTKTYTNSVQWRVPLGLGFAWALFMIGGMTFVPESPRYLVEVGKIE
                     EAKRSIALSNKVSADDPAVMAEVEVVQATVEAEKLAGNASWGEIFSTKTKVFQRLIMG
                     AMIQSLQQLTGDNYFFYYGTTVFTAVGLEDSFETSIVLGIVNFASTFVGIFLVERYGR
                     RRCLLWGAASMTACMVVFASVGVTRLWPNGKKNGSSKGAGNCMIVFTCFYLFCFATTW
                     APIPFVVNSETFPLRVKSKCMAIAQACNWIWGFLIGFFTPFISGAIDFYYGYVFMGCL
                     VFSYFYVFFFVPETKGLTLEEVNTLWEEGVLPWKSPSWVPPNKRGTDYNADDLMHDDQ
                     PFYKKMFGKK"
     gene            complement(<290913..>292625)
                     /gene="HXT1"
                     /locus_tag="YHR094C"
                     /gene_synonym="HOR4"
                     /db_xref="GeneID:856494"
     mRNA            complement(<290913..>292625)
                     /gene="HXT1"
                     /locus_tag="YHR094C"
                     /gene_synonym="HOR4"
                     /product="hexose transporter HXT1"
                     /transcript_id="NM_001179224.1"
                     /db_xref="GI:296145473"
                     /db_xref="GeneID:856494"
     CDS             complement(290913..292625)
                     /gene="HXT1"
                     /locus_tag="YHR094C"
                     /gene_synonym="HOR4"
                     /note="Low-affinity glucose transporter of the major
                     facilitator superfamily; expression is induced by Hxk2p in
                     the presence of glucose and repressed by Rgt1p when
                     glucose is limiting; HXT1 has a paralog, HXT6, what arose
                     from the whole genome duplication"
                     /codon_start=1
                     /product="hexose transporter HXT1"
                     /protein_id="NP_011962.1"
                     /db_xref="GI:6321886"
                     /db_xref="SGD:S000001136"
                     /db_xref="GeneID:856494"
                     /translation="MNSTPDLISPQKSNSSNSYELESGRSKAMNTPEGKNESFHDNLS
                     ESQVQPAVAPPNTGKGVYVTVSICCVMVAFGGFIFGWDTGTISGFVAQTDFLRRFGMK
                     HHDGSHYLSKVRTGLIVSIFNIGCAIGGIVLAKLGDMYGRRIGLIVVVVIYTIGIIIQ
                     IASINKWYQYFIGRIISGLGVGGITVLSPMLISEVAPSEMRGTLVSCYQVMITLGIFL
                     GYCTNFGTKNYSNSVQWRVPLGLCFAWALFMIGGMMFVPESPRYLVEAGRIDEARASL
                     AKVNKCPPDHPYIQYELETIEASVEEMRAAGTASWGELFTGKPAMFQRTMMGIMIQSL
                     QQLTGDNYFFYYGTIVFQAVGLSDSFETSIVFGVVNFFSTCCSLYTVDRFGRRNCLMW
                     GAVGMVCCYVVYASVGVTRLWPNGQDQPSSKGAGNCMIVFACFYIFCFATTWAPIAYV
                     VISECFPLRVKSKCMSIASAANWIWGFLISFFTPFITGAINFYYGYVFMGCMVFAYFY
                     VFFFVPETKGLSLEEVNDMYAEGVLPWKSASWVPVSKRGADYNADDLMHDDQPFYKSL
                     FSRK"
     gene            complement(<294669..>296447)
                     /gene="HXT5"
                     /locus_tag="YHR096C"
                     /db_xref="GeneID:856496"
     mRNA            complement(<294669..>296447)
                     /gene="HXT5"
                     /locus_tag="YHR096C"
                     /product="hexose transporter HXT5"
                     /transcript_id="NM_001179226.1"
                     /db_xref="GI:296145474"
                     /db_xref="GeneID:856496"
     CDS             complement(294669..296447)
                     /gene="HXT5"
                     /locus_tag="YHR096C"
                     /note="Hexose transporter with moderate affinity for
                     glucose; induced in the presence of non-fermentable carbon
                     sources, induced by a decrease in growth rate, contains an
                     extended N-terminal domain relative to other HXTs; HXT5
                     has a paralog, HXT3, that arose from the whole genome
                     duplication"
                     /codon_start=1
                     /product="hexose transporter HXT5"
                     /protein_id="NP_011964.1"
                     /db_xref="GI:6321888"
                     /db_xref="SGD:S000001138"
                     /db_xref="GeneID:856496"
                     /translation="MSELENAHQGPLEGSATVSTNSNSYNEKSGNSTAPGTAGYNDNL
                     AQAKPVSSYISHEGPPKDELEELQKEVDKQLEKKSKSDLLFVSVCCLMVAFGGFVFGW
                     DTGTISGFVRQTDFIRRFGSTRANGTTYLSDVRTGLMVSIFNIGCAIGGIVLSKLGDM
                     YGRKIGLMTVVVIYSIGIIIQIASIDKWYQYFIGRIISGLGVGGITVLAPMLISEVSP
                     KQLRGTLVSCYQLMITFGIFLGYCTNFGTKNYSNSVQWRVPLGLCFAWSIFMIVGMTF
                     VPESPRYLVEVGKIEEAKRSLARANKTTEDSPLVTLEMENYQSSIEAERLAGSASWGE
                     LVTGKPQMFRRTLMGMMIQSLQQLTGDNYFFYYGTTIFQAVGLEDSFETAIVLGVVNF
                     VSTFFSLYTVDRFGRRNCLLWGCVGMICCYVVYASVGVTRLWPNGQDQPSSKGAGNCM
                     IVFACFYIFCFATTWAPVAYVLISESYPLRVRGKAMSIASACNWIWGFLISFFTPFIT
                     SAINFYYGYVFMGCMVFAYFYVFFFVPETKGLTLEEVNEMYEENVLPWKSTKWIPPSR
                     RTTDYDLDATRNDPRPFYKRMFTKEK"
     rep_origin      297060..297179
                     /note="ARS815;
                     Putative replication origin; identified in multiple array
                     studies, not yet confirmed by plasmid-based assay"
                     /db_xref="SGD:S000130150"
     gene            complement(<297385..>298609)
                     /locus_tag="YHR097C"
                     /db_xref="GeneID:856497"
     mRNA            complement(join(<297385..298360,298485..>298609))
                     /locus_tag="YHR097C"
                     /product="hypothetical protein"
                     /transcript_id="NM_001179227.1"
                     /db_xref="GI:296145475"
                     /db_xref="GeneID:856497"
     CDS             complement(join(297385..298360,298485..298609))
                     /locus_tag="YHR097C"
                     /note="hypothetical protein; green fluorescent protein
                     (GFP)-fusion protein localizes to the cytoplasm and the
                     nucleus; YHR097C has a paralog, PAL1, that arose from the
                     whole genome duplication"
                     /codon_start=1
                     /product="hypothetical protein"
                     /protein_id="NP_011965.1"
                     /db_xref="GI:6321889"
                     /db_xref="SGD:S000001139"
                     /db_xref="GeneID:856497"
                     /translation="MNQTGRTIGGPQNGVNTVINPFRVSPSEDRVSSRDETPRNYNNP
                     FLNEDDTRRAHNSSVSNSRQERLPSYEEAAGTPKQQAPYPKEKKRSSGSNSHQHNHHH
                     HRRTSHGHRDKDKQKSKSRTKVKPPKNVDTIDKMDVTGLFGGSFHHDGPFDACTPQRN
                     KNNKVAPVLAFPADGPNNTVGGRTSKKSTLDEVFGRETVDDDSETLNQLQDRAYLFNK
                     ANSSTTTLDAIKPNSKNITQFDSKMKTELVHGPITMGLGSTTFLDGAPASSAAIEQDV
                     INHAQESRRKNSIARKKSLPSRRHLQVNNNNLKLVKTHSGHLEQKDVDDNRTSVPVTA
                     TQGSGHEDVVKKENTGNKLLRRVKSLKTSKKH"
     gene            complement(<299145..>301934)
                     /gene="SFB3"
                     /locus_tag="YHR098C"
                     /gene_synonym="LST1"
                     /db_xref="GeneID:856498"
     mRNA            complement(<299145..>301934)
                     /gene="SFB3"
                     /locus_tag="YHR098C"
                     /gene_synonym="LST1"
                     /product="Sfb3p"
                     /transcript_id="NM_001179228.1"
                     /db_xref="GI:296145476"
                     /db_xref="GeneID:856498"
     CDS             complement(299145..301934)
                     /gene="SFB3"
                     /locus_tag="YHR098C"
                     /gene_synonym="LST1"
                     /note="Component of the Sec23p-Sfb3p heterodimer of the
                     COPII vesicle coat; COPII coat is required for cargo
                     selection during vesicle formation in ER to Golgi
                     transport; homologous to Sec24p and Sfb2p"
                     /codon_start=1
                     /product="Sfb3p"
                     /protein_id="NP_011966.1"
                     /db_xref="GI:6321890"
                     /db_xref="SGD:S000001140"
                     /db_xref="GeneID:856498"
                     /translation="MSQQNILAASVSALSLDESTVHTGGASSKKSRRPHRAYHNFSSG
                     TVPTLGNSPYTTPQLNQQDGFQQPQAFTPKQFGGFNNGSGSVMSTPVMVSQERFGASE
                     ASSPYGQSMLDMTAPQPTSHIVPTQRFEDQAQYLQRSFETCRDSVPPLPTTQFYCVDQ
                     GSCDPHLMSLSMYNIPESEHLRAATKLPLGLTIQPFSTLTPNDAEVPTIPLPMDGTPL
                     RCRRCRAYANPKFQFTYDSSVICNICRVKMQVPGEHFAPMGPNGQRSDLNEKSELLHG
                     TVDFLVPSIYNAIQEKELLPLHYVFLIDVSLLANENGSSLAMVEGVRSCIEYISDFQP
                     NCEVAIIVYDNKLRFFNLRPDLDNAQEYIVSELDDVFLPFYNGLFVKPGNSMKIINDT
                     LIKISGYISTDKYSHVPQVCYGSALQAAKLALDTVTGGQGGKIICSLNSLPTIGNGNL
                     SLKRDNAHIAHVKCDNGFYKKLASDFLKSYISLDLYVTNAGFIDMATVGHPVEMTSGI
                     LKYYPHFQQETDAFTLVNDMVTNVSNIVGYQALLKVRCSTGLSVEQYYCDSSDNTDHD
                     PIIPVLTRDTTLDVLLKYDSKIKTGTDVHFQTALLYTDIDGVRKVRSINTSGAVSNNI
                     REIFKFINQNPVMRIMIKDVIKTLGDCDFVKIRRLIDDKMVEILTQYRGLVSSNSSTQ
                     LILPDSIKTLPAYMLAFEKSELMKPNAQSTRGNERIYDLLKYDSLNSAQLCYKLYPQI
                     VPFHVLLEETDLTFYDANDKLLQINSSSINNLSVRASHSNFINGGCYLIFQGDTIYLW
                     FNENTNRMLLQDLLSVDESLPVSQISLFSGTLPETGTSINQKASNVIKNWQQVVNKSS
                     LPLVLLRPNVDQYYSNVMSQLLCEDKTVNRIESYDNYLVIMHKKIQEKLQKDDFIKVS
                     TAATHENIHQKFVQF"
     gene            <302761..>313995
                     /gene="TRA1"
                     /locus_tag="YHR099W"
                     /db_xref="GeneID:856499"
     mRNA            <302761..>313995
                     /gene="TRA1"
                     /locus_tag="YHR099W"
                     /product="histone acetyltransferase TRA1"
                     /transcript_id="NM_001179229.1"
                     /db_xref="GI:296145477"
                     /db_xref="GeneID:856499"
     CDS             302761..313995
                     /gene="TRA1"
                     /locus_tag="YHR099W"
                     /note="Subunit of SAGA and NuA4 histone acetyltransferase
                     complexes; interacts with acidic activators (e.g., Gal4p)
                     which leads to transcription activation; similar to human
                     TRRAP, which is a cofactor for c-Myc mediated oncogenic
                     transformation"
                     /codon_start=1
                     /product="histone acetyltransferase TRA1"
                     /protein_id="NP_011967.1"
                     /db_xref="GI:6321891"
                     /db_xref="SGD:S000001141"
                     /db_xref="GeneID:856499"
                     /translation="MSLTEQIEQFASRFRDDDATLQSRYSTLSELYDIMELLNSPEDY
                     HFFLQAVIPLLLNQLKEVPISYDAHSPEQKLRNSMLDIFNRCLMNQTFQPYAMEVLEF
                     LLSVLPKENEENGILCMKVLTTLFKSFKSILQDKLDSFIRIIIQIYKNTPNLINQTFY
                     EAGKAEQGDLDSPKEPQADELLDEFSKNDEEKDFPSKQSSTEPRFENSTSSNGLRSSM
                     FSFKILSECPITMVTLYSSYKQLTSTSLPEFTPLIMNLLNIQIKQQQEAREQAESRGE
                     HFTSISTEIINRPAYCDFILAQIKATSFLAYVFIRGYAPEFLQDYVNFVPDLIIRLLQ
                     DCPSELSSARKELLHATRHILSTNYKKLFLPKLDYLFDERILIGNGFTMHETLRPLAY
                     STVADFIHNIRSELQLSEIEKTIKIYTGYLLDESLALTVQIMSAKLLLNLVERILKLG
                     KENPQEAPRAKKLLMIIIDSYMNRFKTLNRQYDTIMKYYGRYETHKKEKAEKLKNSIQ
                     DNDKESEEFMRKVLEPSDDDHLMPQPKKEDINDSPDVEMTESDKVVKNDVEMFDIKNY
                     APILLLPTPTNDPIKDAFYLYRTLMSFLKTIIHDLKVFNPPPNEYTVANPKLWASVSR
                     VFSYEEVIVFKDLFHECIIGLKFFKDHNEKLSPETTKKHFDISMPSLPVSATKDAREL
                     MDYLAFMFMQMDNATFNEIIEQELPFVYERMLEDSGLLHVAQSFLTSEITSPNFAGIL
                     LRFLKGKLKDLGNVDFNTSNVLIRLFKLSFMSVNLFPNINEVVLLPHLNDLILNSLKY
                     STTAEEPLVYFYLIRTLFRSIGGGRFENLYRSIKPILQVLLQSLNQMILTARLPHERE
                     LYVELCITVPVRLSVLAPYLPFLMKPLVFALQQYPDLVSQGLRTLELCIDNLTAEYFD
                     PIIEPVIDDVSKALFNLLQPQPFNHAISHNVVRILGKLGGRNRQFLKPPTDLTEKTEL
                     DIDAIADFKINGMPEDVPLSVTPGIQSALNILQSYKSDIHYRKSAYKYLTCVLLLMTK
                     SSAEFPTNYTELLKTAVNSIKLERIGIEKNFDLEPTVNKRDYSNQENLFLRLLESVFY
                     ATSIKELKDDAMDLLNNLLDHFCLLQVNTTLLNKRNYNGTFNIDLKNPNFMLDSSLIL
                     DAIPFALSYYIPEVREVGVLAYKRIYEKSCLIYGEELALSHSFIPELAKQFIHLCYDE
                     TYYNKRGGVLGIKVLIDNVKSSSVFLKKYQYNLANGLLFVLKDTQSEAPSAITDSAEK
                     LLIDLLSITFADVKEEDLGNKVLENTLTDIVCELSNANPKVRNACQKSLHTISNLTGI
                     PIVKLMDHSKQFLLSPIFAKPLRALPFTMQIGNVDAITFCLSLPNTFLTFNEELFRLL
                     QESIVLADAEDESLSTNIQKTTEYSTSEQLVQLRIACIKLLAIALKNEEFATAQQGNI
                     RIRILAVFFKTMLKTSPEIINTTYEALKGSLAENSKLPKELLQNGLKPLLMNLSDHQK
                     LTVPGLDALSKLLELLIAYFKVEIGRKLLDHLTAWCRVEVLDTLFGQDLAEQMPTKII
                     VSIINIFHLLPPQADMFLNDLLLKVMLLERKLRLQLDSPFRTPLARYLNRFHNPVTEY
                     FKKNMTLRQLVLFMCNIVQRPEAKELAEDFEKELDNFYDFYISNIPKNQVRVVSFFTN
                     MVDLFNTMVITNGDEWLKKKGNMILKLKDMLNLTLKTIKENSFYIDHLQLNQSIAKFQ
                     ALYLRFTELSERDQNPLLLDFIDFSFSNGIKASYSLKKFIFHNIIASSNKEKQNNFIN
                     DATLFVLSDKCLDARIFVLKNVINSTLIYEVATSGSLKSYLVEDKKPKWLELLHNKIW
                     KNSNAILAYDVLDHHDLFRFELLQLSAIFIKADPEIIAEIKKDIIKFCWNFIKLEDTL
                     IKQSAYLVTSYFISKFDFPIKVVTQVFVALLRSSHVEARYLVKQSLDVLTPVLHERMN
                     AAGTPDTWINWVKRVMVENSSSQNNILYQFLISHPDLFFNSRDLFISNIIHHMNKITF
                     MSNSNSDSHTLAIDLASLILYWENKTLEITNVNNTKTDSDGDVVMSDSKSDINPVEAD
                     TTAIIVDANNNSPISLHLREACTAFLIRYVCASNHRAIETELGLRAINILSELISDKH
                     WTNVNVKLVYFEKFLIFQDLDSENILYYCMNALDVLYVFFKNKTKEWIMENLPTIQNL
                     LEKCIKSDHHDVQEALQKVLQVIMKAIKAQGVSVIIEEESPGKTFIQMLTSVITQDLQ
                     ETSSVTAGVTLAWVLFMNFPDNIVPLLTPLMKTFSKLCKDHLSISQPKDAMALEEARI
                     TTKLLEKVLYILSLKVSLLGDSRRPFLSTVALLIDHSMDQNFLRKIVNMSRSWIFNTE
                     IFPTVKEKAAILTKMLAFEIRGEPSLSKLFYEIVLKLFDQEHFNNTEITVRMEQPFLV
                     GTRVEDIGIRKRFMTILDNSLERDIKERLYYVIRDQNWEFIADYPWLNQALQLLYGSF
                     NREKELSLKNIYCLSPPSILQEYLPENAEMVTEVNDLELSNFVKGHIASMQGLCRIIS
                     SDFIDSLIEIFYQDPKAIHRAWVTLFPQVYKSIPKNEKYGFVRSIITLLSKPYHTRQI
                     SSRTNVINMLLDSISKIESLELPPHLVKYLAISYNAWYQSINILESIQSNTSIDNTKI
                     IEANEDALLELYVNLQEEDMFYGLWRRRAKYTETNIGLSYEQIGLWDKAQQLYEVAQV
                     KARSGALPYSQSEYALWEDNWIQCAEKLQHWDVLTELAKHEGFTDLLLECGWRVADWN
                     SDRDALEQSVKSVMDVPTPRRQMFKTFLALQNFAESRKGDQEVRKLCDEGIQLSLIKW
                     VSLPIRYTPAHKWLLHGFQQYMEFLEATQIYANLHTTTVQNLDSKAQEIKRILQAWRD
                     RLPNTWDDVNMWNDLVTWRQHAFQVINNAYLPLIPALQQSNSNSNINTHAYRGYHEIA
                     WVINRFAHVARKHNMPDVCISQLARIYTLPNIEIQEAFLKLREQAKCHYQNMNELTTG
                     LDVISNTNLVYFGTVQKAEFFTLKGMFLSKLRAYEEANQAFATAVQIDLNLAKAWAQW
                     GFFNDRRLSEEPNNISFASNAISCYLQAAGLYKNSKIRELLCRILWLISIDDASGMLT
                     NAFDSFRGEIPVWYWITFIPQLLTSLSHKEANMVRHILIRIAKSYPQALHFQLRTTKE
                     DFAVIQRQTMAVMGDKPDTNDRNGRRQPWEYLQELNNILKTAYPLLALSLESLVAQIN
                     DRFKSTTDEDLFRLINVLLIDGTLNYNRLPFPRKNPKLPENTEKNLVKFSTTLLAPYI
                     RPKFNADFIDNKPDYETYIKRLRYWRRRLENKLDRASKKENLEVLCPHLSNFHHQKFE
                     DIEIPGQYLLNKDNNVHFIKIARFLPTVDFVRGTHSSYRRLMIRGHDGSVHSFAVQYP
                     AVRHSRREERMFQLYRLFNKSLSKNVETRRRSIQFNLPIAIPLSPQVRIMNDSVSFTT
                     LHEIHNEFCKKKGFDPDDIQDFMADKLNAAHDDALPAPDMTILKVEIFNSIQTMFVPS
                     NVLKDHFTSLFTQFEDFWLFRKQFASQYSSFVFMSYMMMINNRTPHKIHVDKTSGNVF
                     TLEMLPSRFPYERVKPLLKNHDLSLPPDSPIFHNNEPVPFRLTPNIQSLIGDSALEGI
                     FAVNLFTISRALIEPDNELNTYLALFIRDEIISWFSNLHRPIIENPQLREMVQTNVDL
                     IIRKVAQLGHLNSTPTVTTQFILDCIGSAVSPRNLARTDVNFMPWF"
     gene            complement(<314116..>314673)
                     /gene="GEP4"
                     /locus_tag="YHR100C"
                     /db_xref="GeneID:856500"
     mRNA            complement(<314116..>314673)
                     /gene="GEP4"
                     /locus_tag="YHR100C"
                     /product="Gep4p"
                     /transcript_id="NM_001179230.1"
                     /db_xref="GI:296145478"
                     /db_xref="GeneID:856500"
     CDS             complement(314116..314673)
                     /gene="GEP4"
                     /locus_tag="YHR100C"
                     /EC_number="3.1.3.27"
                     /note="Mitochondrial phosphatidylglycerophosphatase (PGP
                     phosphatase); dephosphorylates
                     phosphatidylglycerolphosphate to generate
                     phosphatidylglycerol, an essential step during cardiolipin
                     biosynthesis; null mutant is sensitive to tunicamycin,
                     DTT"
                     /codon_start=1
                     /product="Gep4p"
                     /protein_id="NP_011968.1"
                     /db_xref="GI:6321892"
                     /db_xref="SGD:S000001142"
                     /db_xref="GeneID:856500"
                     /translation="MNISGTLNTLRLLYNPSLCKPSLVVPTFNDLPIPIHDSIKAVVL
                     DKDNCIAFPHDDKIWPDYLQHWETLRSKYSNKALLIVSNTAGSNSDKDYSQAKLLEDK
                     TGIPVLRHSTKKPGCHNEILDYFYRNKTITNPKEVAVVGDRLFTDILMANLMGSYGVW
                     IRDGVKVSANPLSKFEKKLYNFLGF"
     gene            complement(<314874..>315968)
                     /gene="BIG1"
                     /locus_tag="YHR101C"
                     /db_xref="GeneID:856501"
     mRNA            complement(join(<314874..315771,315859..>315968))
                     /gene="BIG1"
                     /locus_tag="YHR101C"
                     /product="Big1p"
                     /transcript_id="NM_001179231.1"
                     /db_xref="GI:296145479"
                     /db_xref="GeneID:856501"
     CDS             complement(join(314874..315771,315859..315968))
                     /gene="BIG1"
                     /locus_tag="YHR101C"
                     /note="Integral membrane protein of the endoplasmic
                     reticulum; required for normal content of cell wall
                     beta-1,6-glucan"
                     /codon_start=1
                     /product="Big1p"
                     /protein_id="NP_011969.1"
                     /db_xref="GI:6321893"
                     /db_xref="SGD:S000001143"
                     /db_xref="GeneID:856501"
                     /translation="MQTVLKYLLLIMCGSFCASEELQNQTNVPAIFFSYKLTPGILKY
                     QEDYDRAVTLPRDTFIEAAEKFLGVCNADTYVFINQPGLRKLDFLEFETEFVSLQRYI
                     RRSSTAIKFEKVDLLPQDLYYDLAEFVKEYCNVDQVLNLRGNNTEDFQPFIDSEKRVI
                     IIEYPKLPEDTNERKEAFRHYDKYLRTILAQIPSPEQNVIYTSLNPGTTLAHESIIPI
                     QIFPDIFDIKSRVGEVEQNNRVLDVPRLSFNDYTPRFSEPPSEYVSIFDSQLIENNRG
                     LLQLIFTILVGYILIQFFFTKKTIVDEKITNKKDNVKQTSPQLLKKVQEIQKKPSQQV
                     S"
     gene            <316572..>319814
                     /gene="KIC1"
                     /locus_tag="YHR102W"
                     /gene_synonym="NRK1"
                     /db_xref="GeneID:856502"
     mRNA            <316572..>319814
                     /gene="KIC1"
                     /locus_tag="YHR102W"
                     /gene_synonym="NRK1"
                     /product="putative serine/threonine protein kinase KIC1"
                     /transcript_id="NM_001179232.1"
                     /db_xref="GI:296145480"
                     /db_xref="GeneID:856502"
     CDS             316572..319814
                     /gene="KIC1"
                     /locus_tag="YHR102W"
                     /gene_synonym="NRK1"
                     /EC_number="2.7.11.1"
                     /note="Protein kinase of the PAK/Ste20 family, required
                     for cell integrity; physically interacts with Cdc31p
                     (centrin), which is a component of the spindle pole body;
                     part of the RAM network that regulates cellular polarity
                     and morphogenesis"
                     /codon_start=1
                     /product="putative serine/threonine protein kinase KIC1"
                     /protein_id="NP_011970.1"
                     /db_xref="GI:6321894"
                     /db_xref="SGD:S000001144"
                     /db_xref="GeneID:856502"
                     /translation="MTTKPQNSKQGLAEGEMDVSSLFKRTEVIGRGKFGVVYKGYNVK
                     TGRVYAIKVLNLDSDSDEVEDVQREIQFLASLKQISNITRYYGSYLKDTSLWIIMEHC
                     AGGSLRSLLRPGKIDEKYIGVIMRELLVALKCIHKDNVIHRDIKAANVLITNEGNVKL
                     CDFGVAAQVNQTSLRRQTMAGTPYWMAPEVIMEGVYYDTKVDIWSLGITTYEIATGNP
                     PYCDVEALRAMQLIIKSKPPRLEDRSYSTSLKEFIALCLDEDPKERLSADDLLKSKFI
                     RAHKATPTSILKELISRYLLFRDKNKNKYKIEGSIPENEPSKPSEAPKPSQNGGGDEA
                     QKSIASNDNEIKRVNEGDVEMKWDFDSLSSSDYIIENNINLDALAEDNNEWATAQHDL
                     FNYAYPDEDSYYFDPTSHNTRPFVYQGTTIGKGYPGTIAQNSTLNAPVTNNYTNSKYP
                     SKMVAGTTNTSGTHTAGPMTSSKRLESKAPKQLLELFEDNEIITAENDVNTEAPKISK
                     SISSLNAGNSSRDDFIPSISNEVNGNINNNKMRPHLPPLSSGNNYYSQSTPALPLLQT
                     KFNKTSKGPPTSGLTTAPTSIEIEIPEELPNSALPTPASADPVLIPSTKARSSTVTAG
                     TPSSSSSIQYKSPSNVPRRLTVSNNRPEHCPSTITNQKLGSAVASNSGISSTPNNSNN
                     YNNNTDSENSRGSSGSNTANSTQMGITNPGNVTKLSTHKASSPSRPLFGVGTSPNRKP
                     AGSPTQNIGHNSTHTNLAPPPTMKPMANSKDNKDILLQPLNSIPSSSTLNTISGNSSN
                     NLTSSNYFSNEKEGSRVNGDFKRNNPNLKLQMPLPTPVVRNKLLDPNTATSQNNNGMP
                     GSAGISTNENINQFGFNTSSASNIPVSMTPISEKHIDFGGKIKRSQSISNRKNSSASE
                     HPLNILGSSVSGNVSGIGNNNVGSNNNSGPNNSVPLSANTGNTTIKANSTTIATSSSA
                     AASTTAPISQQTIPSGTQFNHILSSAATAANSVNSLGFGMCPPPQSLQMEMFLDLESF
                     LPGKQRRVDRKPQVLKELENLLQMFEEGLPCIEHALKEQLISTPIKDNEH"
     gene            <320414..>322972
                     /gene="SBE22"
                     /locus_tag="YHR103W"
                     /db_xref="GeneID:856503"
     mRNA            <320414..>322972
                     /gene="SBE22"
                     /locus_tag="YHR103W"
                     /product="Sbe22p"
                     /transcript_id="NM_001179233.1"
                     /db_xref="GI:296145481"
                     /db_xref="GeneID:856503"
     CDS             320414..322972
                     /gene="SBE22"
                     /locus_tag="YHR103W"
                     /note="Protein involved in bud growth; involved in the
                     transport of cell wall components from the Golgi to the
                     cell surface; similar in structure and functionally
                     redundant with Sbe2p; SBE22 has a paralog, SBE2, that
                     arose from the whole genome duplication"
                     /codon_start=1
                     /product="Sbe22p"
                     /protein_id="NP_011971.1"
                     /db_xref="GI:6321895"
                     /db_xref="SGD:S000001145"
                     /db_xref="GeneID:856503"
                     /translation="MTSIQERGTSAHLHSLKEGEASDRSSEMLPKQRSIIGSHVQRPP
                     SQTTLGRSRAGSNTMNKVSGLDIARRPSENLLSNMNCSDNGNGGNMLNSFVNSALPPP
                     KVNPAQTRRERPASNSSIGTKTTEVFSSTSASSSLGDTSDEGEGSDADKSKINTFPSI
                     LMEKATQGRGADGNGMRSASNNTIVEATTDGSKMALQKSMSFDDTAAEKTMNKSRHSY
                     QEQFSSKKSQSSLLNSKQRSRAKSQTCSSTGYNNSSILKTFGISSKISNSSDRIEASS
                     LEFNVPSQKPLNCKPLTPSQKYRLRKEQSEMNLRNTIKRKEKFYDSQEQILELQEGDV
                     DDSLIWNVPMASLSTNSFLASAKPDDMNNLAGKNDLSEYTGGLVNDNSEISYTKQNHR
                     YSNISFASTTSNASLLDFNEMPTSPIPGLNKVTDFQFIQDTTKSLASVYLHSSNRLSR
                     SKLSERTKSSDFLPIELKEAQNQGMEDLILVSENKLDVVSHSRPSWLPPKDRQEKKLH
                     ERQINKSMSVASLDQLGKNKDREEKLIRDETNRQKYVLLLDRDITRNSSLQSLSKMVW
                     DTPFSDETRSTIYSEILQSKTRFITKNYIQPFHELQELLTKMGDFPKNKEIEISQLIE
                     TSLRRKVSGLHDICPDLMLLLKIKSISSQGIVTGDELLFHHFLVSESFQNLGLNEIWN
                     IVNLVQMTCFNDLCKEKFDAKVLERKGVVAGYLSQNEEFKDEFNTECINSTTWWNILE
                     RIDHKLFMWIMDIIVVNNSQSYKNSPINEDEFVNKDWEYYRSKKVVINYKILISFALN
                     VLLNYHFGFTDLRSLCNVNDQRFCIPVFINDEFVDADTVNAVFIKKWAHYYKKF"
     gene            <323409..>324392
                     /gene="GRE3"
                     /locus_tag="YHR104W"
                     /db_xref="GeneID:856504"
     mRNA            <323409..>324392
                     /gene="GRE3"
                     /locus_tag="YHR104W"
                     /product="trifunctional aldehyde reductase/xylose
                     reductase/glucose 1-dehydrogenase (NADP(+))"
                     /transcript_id="NM_001179234.1"
                     /db_xref="GI:296145482"
                     /db_xref="GeneID:856504"
     CDS             323409..324392
                     /gene="GRE3"
                     /locus_tag="YHR104W"
                     /EC_number="1.1.1.21"
                     /EC_number="1.1.1.-"
                     /note="Aldose reductase; involved in methylglyoxal,
                     d-xylose, arabinose, and galactose metabolism; stress
                     induced (osmotic, ionic, oxidative, heat shock, starvation
                     and heavy metals); regulated by the HOG pathway; protein
                     abundance increases in response to DNA replication stress"
                     /codon_start=1
                     /product="trifunctional aldehyde reductase/xylose
                     reductase/glucose 1-dehydrogenase (NADP(+))"
                     /protein_id="NP_011972.1"
                     /db_xref="GI:6321896"
                     /db_xref="SGD:S000001146"
                     /db_xref="GeneID:856504"
                     /translation="MSSLVTLNNGLKMPLVGLGCWKIDKKVCANQIYEAIKLGYRLFD
                     GACDYGNEKEVGEGIRKAISEGLVSRKDIFVVSKLWNNFHHPDHVKLALKKTLSDMGL
                     DYLDLYYIHFPIAFKYVPFEEKYPPGFYTGADDEKKGHITEAHVPIIDTYRALEECVD
                     EGLIKSIGVSNFQGSLIQDLLRGCRIKPVALQIEHHPYLTQEHLVEFCKLHDIQVVAY
                     SSFGPQSFIEMDLQLAKTTPTLFENDVIKKVSQNHPGSTTSQVLLRWATQRGIAVIPK
                     SSKKERLLGNLEIEKKFTLTEQELKDISALNANIRFNDPWTWLDGKFPTFA"
     gene            <324766..>325410
                     /gene="YPT35"
                     /locus_tag="YHR105W"
                     /db_xref="GeneID:856505"
     mRNA            <324766..>325410
                     /gene="YPT35"
                     /locus_tag="YHR105W"
                     /product="Ypt35p"
                     /transcript_id="NM_001179235.1"
                     /db_xref="GI:296145483"
                     /db_xref="GeneID:856505"
     CDS             324766..325410
                     /gene="YPT35"
                     /locus_tag="YHR105W"
                     /note="Endosomal hypothetical protein; contains a phox
                     (PX) homology domain; binds to both
                     phosphatidylinositol-3-phosphate (PtdIns(3)P) and proteins
                     involved in ER-Golgi or vesicular transport"
                     /codon_start=1
                     /product="Ypt35p"
                     /protein_id="NP_011973.1"
                     /db_xref="GI:6321897"
                     /db_xref="SGD:S000001147"
                     /db_xref="GeneID:856505"
                     /translation="MSDKISFLPPEPIQLLDEDSTEPELDIDSQQENEGPISASNSND
                     STSHSNDCGATITRTRPRRSSSINANFSFQKAHVSDCTIVNGDHGTKFAVWRITVFLE
                     PNLKAFAAKRESYKIQTYKRYSDFVRLRENLLTRIKTAKPEKLNCLQIPHLPPSVQWY
                     SSWKYQEVNLNKDWLAKRQRGLEYFLNHIILNSSLVEMTKDILIQFLEPSKRVA"
     gene            <325598..>326626
                     /gene="TRR2"
                     /locus_tag="YHR106W"
                     /db_xref="GeneID:856506"
     mRNA            <325598..>326626
                     /gene="TRR2"
                     /locus_tag="YHR106W"
                     /product="thioredoxin-disulfide reductase TRR2"
                     /transcript_id="NM_001179236.1"
                     /db_xref="GI:296145484"
                     /db_xref="GeneID:856506"
     CDS             325598..326626
                     /gene="TRR2"
                     /locus_tag="YHR106W"
                     /EC_number="1.8.1.9"
                     /note="Mitochondrial thioredoxin reductase; involved in
                     protection against oxidative stress, required with Glr1p
                     to maintain the redox state of Trx3p; contains active-site
                     motif (CAVC) present in prokaryotic orthologs; binds NADPH
                     and FAD; TRR2 has a paralog, TRR1, that arose from the
                     whole genome duplication"
                     /codon_start=1
                     /product="thioredoxin-disulfide reductase TRR2"
                     /protein_id="NP_011974.1"
                     /db_xref="GI:6321898"
                     /db_xref="SGD:S000001148"
                     /db_xref="GeneID:856506"
                     /translation="MIKHIVSPFRTNFVGISKSVLSRMIHHKVTIIGSGPAAHTAAIY
                     LARAEMKPTLYEGMMANGIAAGGQLTTTTDIENFPGFPESLSGSELMERMRKQSAKFG
                     TNIITETVSKVDLSSKPFRLWTEFNEDAEPVTTDAIILATGASAKRMHLPGEETYWQQ
                     GISACAVCDGAVPIFRNKPLAVIGGGDSACEEAEFLTKYASKVYILVRKDHFRASVIM
                     QRRIEKNPNIIVLFNTVALEAKGDGKLLNMLRIKNTKSNVENDLEVNGLFYAIGHSPA
                     TDIVKGQVDEEETGYIKTVPGSSLTSVPGFFAAGDVQDSRYRQAVTSAGSGCIAALDA
                     ERYLSAQE"
     gene            complement(<326813..>328036)
                     /gene="CDC12"
                     /locus_tag="YHR107C"
                     /gene_synonym="CLA10; PSL7"
                     /db_xref="GeneID:856507"
     mRNA            complement(<326813..>328036)
                     /gene="CDC12"
                     /locus_tag="YHR107C"
                     /gene_synonym="CLA10; PSL7"
                     /product="septin CDC12"
                     /transcript_id="NM_001179237.1"
                     /db_xref="GI:296145485"
                     /db_xref="GeneID:856507"
     CDS             complement(326813..328036)
                     /gene="CDC12"
                     /locus_tag="YHR107C"
                     /gene_synonym="CLA10; PSL7"
                     /note="Component of the septin ring that is required for
                     cytokinesis; septins are GTP-binding proteins that
                     assemble into rod-like hetero-oligomers that can associate
                     with other rods to form filaments; septin rings at the
                     mother-bud neck act as scaffolds for recruiting cell
                     division factors and as barriers to prevent diffusion of
                     specific proteins between mother and daughter cells"
                     /codon_start=1
                     /product="septin CDC12"
                     /protein_id="NP_011975.1"
                     /db_xref="GI:6321899"
                     /db_xref="SGD:S000001149"
                     /db_xref="GeneID:856507"
                     /translation="MSAATATAAPVPPPVGISNLPNQRYKIVNEEGGTFTVMLCGESG
                     LGKTTFINTLFQTVLKRADGQQHRQEPIRKTVEIDITRALLEEKHFELRVNVIDTPGF
                     GDNVNNNKAWQPLVDFIDDQHDSYMRQEQQPYRTKKFDLRVHAVLYFIRPTGHGLKPI
                     DIETMKRLSTRANLIPVIAKADTLTAQELQQFKSRIRQVIEAQEIRIFTPPLDADSKE
                     DAKSGSNPDSAAVEHARQLIEAMPFAIVGSEKKFDNGQGTQVVARKYPWGLVEIENDS
                     HCDFRKLRALLLRTYLLDLISTTQEMHYETYRRLRLEGHENTGEGNEDFTLPAIAPAR
                     KLSHNPRYKEEENALKKYFTDQVKAEEQRFRQWEQNIVNERIRLNGDLEEIQGKVKKL
                     EEQVKSLQVKKSHLK"
     gene            <328303..>330060
                     /gene="GGA2"
                     /locus_tag="YHR108W"
                     /db_xref="GeneID:856508"
     mRNA            <328303..>330060
                     /gene="GGA2"
                     /locus_tag="YHR108W"
                     /product="Gga2p"
                     /transcript_id="NM_001179238.1"
                     /db_xref="GI:296145486"
                     /db_xref="GeneID:856508"
     CDS             328303..330060
                     /gene="GGA2"
                     /locus_tag="YHR108W"
                     /note="Protein that regulates Arf1p, Arf2p to facilitate
                     Golgi trafficking; binds phosphatidylinositol 4-phosphate,
                     which plays a role in TGN localization; has homology to
                     gamma-adaptin; GGA2 has a paralog, GGA1, that arose from
                     the whole genome duplication"
                     /codon_start=1
                     /product="Gga2p"
                     /protein_id="NP_011976.1"
                     /db_xref="GI:6321900"
                     /db_xref="SGD:S000001150"
                     /db_xref="GeneID:856508"
                     /translation="MSHPHSHSIYLSELPVRKPQALGNPLLRKIQRACRMSLAEPDLA
                     LNLDIADYINEKQGAAPRDAAIALAKLINNRESHVAIFALSLLDVLVKNCGYPFHLQI
                     SRKEFLNELVKRFPGHPPLRYSKIQRLILTAIEEWYQTICKHSSYKNDMGYIRDMHRL
                     LKYKGYAFPKISESDLAVLKPSNQLKTASEIQKEQEIAQAAKLEELIRRGKPEDLREA
                     NKLMKIMAGFKEDNAVQAKQAISSELNKLKRKADLLNEMLESPDSQNWDNETTQELHS
                     ALKVAQPKFQKIIEEEQEDDALVQDLLKFNDTVNQLLEKFNLLKNGDSNAASQIHPSH
                     VSAPLQQSSGALTNEINLIDFNDLDEAPSQGNNNTNGTGTPAAAETSVNDLLGDLTDL
                     SISNPSTANQASFGLGGDIVLGSSQPAPPVTTTNNSNNTLDLLGLSTPQSPTNSQAVN
                     SSGFDLLMGFNPTTGTTTAPARTLVNQSPNLKIEFEISRESNSVIRIKSFFTNLSSSP
                     ISNLVFLLAVPKSMSLKLQPQSSNFMIGNAKDGISQEGTIENAPANPSKALKVKWKVN
                     YSVNSTQAEETAVFTLPNV"
     gene            <330310..>332067
                     /gene="CTM1"
                     /locus_tag="YHR109W"
                     /db_xref="GeneID:856509"
     mRNA            <330310..>332067
                     /gene="CTM1"
                     /locus_tag="YHR109W"
                     /product="Ctm1p"
                     /transcript_id="NM_001179239.1"
                     /db_xref="GI:296145487"
                     /db_xref="GeneID:856509"
     CDS             330310..332067
                     /gene="CTM1"
                     /locus_tag="YHR109W"
                     /EC_number="2.1.1.59"
                     /note="Cytochrome c lysine methyltransferase;
                     trimethylates residue 72 of apo-cytochrome c (Cyc1p) in
                     the cytosol; not required for normal respiratory growth"
                     /codon_start=1
                     /product="Ctm1p"
                     /protein_id="NP_011977.1"
                     /db_xref="GI:6321901"
                     /db_xref="SGD:S000001151"
                     /db_xref="GeneID:856509"
                     /translation="MEEVFRFYSNSRNIFIHKSLSLKPSTIDDPKSGYGLFVEPSKFK
                     NDELKSETIQLLRIPKRCTFNINTLLALLGDEDEFSSKEEFQRTNDKIKIALREIMAH
                     PNFSVFLTETNLLIIYFMIFQTIRSRYEIPENIQYYLENVLMSIEVETAMDSIENLAT
                     DYGHYPQIFGLRETLNLFKELFHDVLNLSDIKHLYSAIISRCLEIPERADTKSEEFTV
                     HSTLVPIVDFANHEGTQKNAYFDIDPSNNDVLLLLDTKAVQSELTKPIEVFISYSPTE
                     DLFSMLVTYGFTPDFRGNSQFWTVSFDRCFLRNYDGPDKTTNLRLFYKWMHINPVVPL
                     VKYEHNGKTRWFLNDTTPEFDMLLLPFIPSIDDGKIARWAYDSTCHLMFTKIHCLINP
                     EANEHALMIAENYRSLIKEKESNGDDFINLPPLAWSLRYKDTENDCVRQRHICSEDAV
                     AVLKQEEMQDSTKTKSQFTSFFRKFLEFRRSKIIRPTSDSKVASILYQQELEIIADLA
                     KAIDSSSTIFFSDLNVTLDTEPERLPPLRFLDDYIEISADKQEPSPICEDLSYYTPSR
                     FTDFFQEEVSQYAAFFQDD"
     gene            <332282..>332920
                     /gene="ERP5"
                     /locus_tag="YHR110W"
                     /db_xref="GeneID:856510"
     mRNA            <332282..>332920
                     /gene="ERP5"
                     /locus_tag="YHR110W"
                     /product="Erp5p"
                     /transcript_id="NM_001179240.1"
                     /db_xref="GI:296145488"
                     /db_xref="GeneID:856510"
     CDS             332282..332920
                     /gene="ERP5"
                     /locus_tag="YHR110W"
                     /note="Protein with similarity to Emp24p and Erv25p;
                     member of the p24 family involved in ER to Golgi
                     transport"
                     /codon_start=1
                     /product="Erp5p"
                     /protein_id="NP_011978.1"
                     /db_xref="GI:6321902"
                     /db_xref="SGD:S000001152"
                     /db_xref="GeneID:856510"
                     /translation="MKYNIVHGICLLFAITQAVGAVHFYAKSGETKCFYEHLSRGNLL
                     IGDLDLYVEKDGLFEEDPESSLTITVDETFDNDHRVLNQKNSHTGDVTFTALDTGEHR
                     FCFTPFYSKKSATLRVFIELEIGNVEALDSKKKEDMNSLKGRVGQLTQRLSSIRKEQD
                     AIREKEAEFRNQSESANSKIMTWSVFQLLILLGTCAFQLRYLKNFFVKQKVV"
     gene            <333072..>334394
                     /gene="UBA4"
                     /locus_tag="YHR111W"
                     /gene_synonym="YHR1"
                     /db_xref="GeneID:856511"
     mRNA            <333072..>334394
                     /gene="UBA4"
                     /locus_tag="YHR111W"
                     /gene_synonym="YHR1"
                     /product="Uba4p"
                     /transcript_id="NM_001179241.1"
                     /db_xref="GI:296145489"
                     /db_xref="GeneID:856511"
     CDS             333072..334394
                     /gene="UBA4"
                     /locus_tag="YHR111W"
                     /gene_synonym="YHR1"
                     /EC_number="2.8.1.-"
                     /EC_number="2.7.7.-"
                     /note="E1-like protein that activates Urm1p before
                     urmylation; also acts in thiolation of the wobble base of
                     cytoplasmic tRNAs by adenylating and then thiolating
                     Urm1p; receives sulfur from Tum1p"
                     /codon_start=1
                     /product="Uba4p"
                     /protein_id="NP_011979.1"
                     /db_xref="GI:6321903"
                     /db_xref="SGD:S000001153"
                     /db_xref="GeneID:856511"
                     /translation="MNDYHLEDTTSELEALRLENAQLREQLAKREDSSRDYPLSLEEY
                     QRYGRQMIVEETGGVAGQVKLKNTKVLVVGAGGLGCPALPYLAGAGVGQIGIVDNDVV
                     ETSNLHRQVLHDSSRVGMLKCESARQYITKLNPHINVVTYPVRLNSSNAFDIFKGYNY
                     ILDCTDSPLTRYLVSDVAVNLGITVVSASGLGTEGQLTILNFNNIGPCYRCFYPTPPP
                     PNAVTSCQEGGVIGPCIGLVGTMMAVETLKLILGIYTNENFSPFLMLYSGFPQQSLRT
                     FKMRGRQEKCLCCGKNRTITKEAIEKGEINYELFCGARNYNVCEPDERISVDAFQRIY
                     KDDEFLAKHIFLDVRPSHHYEISHFPEAVNIPIKNLRDMNGDLKKLQEKLPSVEKDSN
                     IVILCRYGNDSQLATRLLKDKFGFSNVRDVRGGYFKYIDDIDQTIPKY"
     gene            complement(<334527..>335663)
                     /locus_tag="YHR112C"
                     /db_xref="GeneID:856512"
     mRNA            complement(<334527..>335663)
                     /locus_tag="YHR112C"
                     /product="putative cystathionine beta-lyase"
                     /transcript_id="NM_001179242.1"
                     /db_xref="GI:296145490"
                     /db_xref="GeneID:856512"
     CDS             complement(334527..335663)
                     /locus_tag="YHR112C"
                     /note="hypothetical protein; localizes to the cytoplasm
                     and nucleus; overexpression affects protein trafficking
                     through the endocytic pathway"
                     /codon_start=1
                     /product="putative cystathionine beta-lyase"
                     /protein_id="NP_011980.1"
                     /db_xref="GI:6321904"
                     /db_xref="SGD:S000001154"
                     /db_xref="GeneID:856512"
                     /translation="MVDLSTALIHGDDKDNRVTDVAPPINVSTTFRYDDDDLIPWTER
                     ENLDFMEKKPVYSRLAHPNSTRLESIFSEILDGYAVIYSSGLAAFYAAMVHYNPKKIF
                     IGQSYHGVRAIANILTRNYGIEQHPLEDIEKCASEGDIVHLESPVNPYGTSSDIESLA
                     RRAHAKGALLIVDSTFASPPLQYAWNFGADIVLYSATKYFGGHSDLLSGVLVVKEEAT
                     SRQLKDDRIYLGTNVANLESFMLLRSLRTYEMRITKQSENATKLVRFLSDHQSEFDKV
                     LKTIYHSSLQTEEFVKKQLVGGYGPVFAITLYTKEQCKQLPLKLKYFHHATSLGGIES
                     LVEWRAMTDPYIDQTLIRVSVGCESANDLIKDLASALKELQDAA"
     gene            <336337..>337809
                     /gene="APE4"
                     /locus_tag="YHR113W"
                     /db_xref="GeneID:856513"
     mRNA            <336337..>337809
                     /gene="APE4"
                     /locus_tag="YHR113W"
                     /product="Ape4p"
                     /transcript_id="NM_001179243.1"
                     /db_xref="GI:296145491"
                     /db_xref="GeneID:856513"
     CDS             336337..337809
                     /gene="APE4"
                     /locus_tag="YHR113W"
                     /EC_number="3.4.11.21"
                     /note="Cytoplasmic aspartyl aminopeptidase with possible
                     vacuole function; Cvt pathway cargo protein; cleaves
                     unblocked N-terminal acidic amino acids from peptide
                     substrates; forms a 12-subunit homo-oligomer; M18
                     metalloprotease family"
                     /codon_start=1
                     /product="Ape4p"
                     /protein_id="NP_011981.1"
                     /db_xref="GI:6321905"
                     /db_xref="SGD:S000001155"
                     /db_xref="GeneID:856513"
                     /translation="MFRIQLRTMSSKTCKSDYPKEFVSFLNSSHSPYHTVHNIKKHLV
                     SNGFKELSERDSWAGHVAQKGKYFVTRNGSSIIAFAVGGKWEPGNPIAITGAHTDSPA
                     LRIKPISKRVSEKYLQVGVETYGGAIWHSWFDKDLGVAGRVFVKDAKTGKSIARLVDL
                     NRPLLKIPTLAIHLDRDVNQKFEFNRETQLLPIGGLQEDKTEAKTEKEINNGEFTSIK
                     TIVQRHHAELLGLIAKELAIDTIEDIEDFELILYDHNASTLGGFNDEFVFSGRLDNLT
                     SCFTSMHGLTLAADTEIDRESGIRLMACFDHEEIGSSSAQGADSNFLPNILERLSILK
                     GDGSDQTKPLFHSAILETSAKSFFLSSDVAHAVHPNYANKYESQHKPLLGGGPVIKIN
                     ANQRYMTNSPGLVLVKRLAEAAKVPLQLFVVANDSPCGSTIGPILASKTGIRTLDLGN
                     PVLSMHSIRETGGSADLEFQIKLFKEFFERYTSIESEIVV"
     gene            <338083..>339984
                     /gene="BZZ1"
                     /locus_tag="YHR114W"
                     /gene_synonym="LSB7"
                     /db_xref="GeneID:856514"
     mRNA            <338083..>339984
                     /gene="BZZ1"
                     /locus_tag="YHR114W"
                     /gene_synonym="LSB7"
                     /product="Bzz1p"
                     /transcript_id="NM_001179244.1"
                     /db_xref="GI:296145492"
                     /db_xref="GeneID:856514"
     CDS             338083..339984
                     /gene="BZZ1"
                     /locus_tag="YHR114W"
                     /gene_synonym="LSB7"
                     /note="SH3 domain protein implicated in regulating actin
                     polymerization; able to recruit actin polymerization
                     machinery through its SH3 domains; colocalizes with
                     cortical actin patches and Las17p; interacts with type I
                     myosins"
                     /codon_start=1
                     /product="Bzz1p"
                     /protein_id="NP_011982.1"
                     /db_xref="GI:6321906"
                     /db_xref="SGD:S000001156"
                     /db_xref="GeneID:856514"
                     /translation="MSADLSIGNEIKDSFKETHKWVQNNLKWLKDIEQFYRERAKLEK
                     DYSERLSRLSAEYFNKKSSTSVPISVGDTPTTTPGSIEAAGVVAWNEILSQTDMISKD
                     HDQLSTDFENHVANQLSGLFTKLDMTLSKINGFNNDMVNKKDNIYHELEKAKKDYDEA
                     CSTMEMARNRYTKASNDRNKKKLDEKEMEMNKCKNEYLIKINQANRTKDKYYFQDVPE
                     VLDLLQDVNEAKTLFLNDLWLKAASVENDLGANVSKRLQAANSVVKQNKPSLNTAIFI
                     KHNLKNWKEPQDFVYKPSPVWHDDEKFAVPSSLEVEDLRIKLAKAENDYNSLQDKTQN
                     ELSKLSTLNKIKHEMKTNEDNINATKFYDTLKEYLNVVSPFTSHETLKLQAEVQIESI
                     QNNVPEEYDLSTDNIDLSKTKKKSGIFSKFKHNILNVDSKPSSGGSTGNGNGGPLHIT
                     SLFNTSRRTRLGSAPNNAGEDSDNNSIRTTSTNNTKKTTQNSSDDGKNKVLYAYVQKD
                     DDEITITPGDKISLVARDTGSGWTKINNDTTGETGLVPTTYIRISSAATVKANDRGPA
                     PEVPPPRRSTLPVRTMEAIYAYEAQGDDEISIDPGDIITVIRGDDGSGWTYGECDGLK
                     GLFPTSYCK"
     gene            complement(<340109..>341359)
                     /gene="DMA1"
                     /locus_tag="YHR115C"
                     /gene_synonym="CHF1"
                     /db_xref="GeneID:856515"
     mRNA            complement(<340109..>341359)
                     /gene="DMA1"
                     /locus_tag="YHR115C"
                     /gene_synonym="CHF1"
                     /product="ubiquitin-conjugating protein DMA1"
                     /transcript_id="NM_001179245.1"
                     /db_xref="GI:296145493"
                     /db_xref="GeneID:856515"
     CDS             complement(340109..341359)
                     /gene="DMA1"
                     /locus_tag="YHR115C"
                     /gene_synonym="CHF1"
                     /EC_number="6.3.2.-"
                     /note="Ubiquitin-protein ligase (E3); controls septin
                     dynamics, spindle position checkpoint (SPOC) with ligase
                     Dma2p by regulating recruitment of Elm1p to bud neck;
                     regulates levels of eIF2 subunit Gcd11p, as well as
                     abundance, localization, and ubiquitination of Cdk
                     inhibitory kinase Swe1p; ubiquitinates cyclin Pcl1p;
                     ortholog of human RNF8, similar to human Chfr; contains
                     FHA, RING fingers; DMA1 has a paralog, DMA2, that arose
                     from the whole genome duplication"
                     /codon_start=1
                     /product="ubiquitin-conjugating protein DMA1"
                     /protein_id="NP_011983.1"
                     /db_xref="GI:6321907"
                     /db_xref="SGD:S000001157"
                     /db_xref="GeneID:856515"
                     /translation="MSTNTVPSSPPNQTPPAASGIATSHDHTKFNNPIRLPISISLTI
                     NDTPNNNSNNNSVSNGLGILPSRTATSLVVANNGSANGNVGATAAAAATVETNTAPAV
                     NTTKSIRHFIYPPNQVNQTEFSLDIHLPPNTSLPERIDQSTLKRRMDKHGLFSIRLTP
                     FIDTSSTSVANQGLFFDPIIRTAGAGSQIIIGRYTERVREAISKIPDQYHPVVFKSKV
                     ISRTHGCFKVDDQGNWFLKDVKSSSGTFLNHQRLSSASTTSKDYLLHDGDIIQLGMDF
                     RGGTEEIYRCVKMKIELNKSWKLKANAFNKEALSRIKNLQKLTTGLEQEDCSICLNKI
                     KPCQAIFISPCAHSWHFHCVRRLVIMNYPQFMCPNCRTNCDLETTLESESESEFENED
                     EDEPDIEMDIDMEINNNLGVRLVD"
     gene            <341665..>342120
                     /gene="COX23"
                     /locus_tag="YHR116W"
                     /db_xref="GeneID:856516"
     mRNA            <341665..>342120
                     /gene="COX23"
                     /locus_tag="YHR116W"
                     /product="Cox23p"
                     /transcript_id="NM_001179246.1"
                     /db_xref="GI:296145494"
                     /db_xref="GeneID:856516"
     CDS             341665..342120
                     /gene="COX23"
                     /locus_tag="YHR116W"
                     /note="Protein that functions in mitochondrial copper
                     homeostasis; mitochondrial intermembrane space protein;
                     essential for functional cytochrome oxidase expression;
                     homologous to Cox17p; contains twin cysteine-x9-cysteine
                     motifs"
                     /codon_start=1
                     /product="Cox23p"
                     /protein_id="NP_011984.1"
                     /db_xref="GI:6321908"
                     /db_xref="SGD:S000001158"
                     /db_xref="GeneID:856516"
                     /translation="MEKPSPTRRQTSSLSTISNGMTMTNDNRDTTNTNSGSTSSNNSQ
                     PSSSSTPPAASGPVTDRTKVNYVPKSDDPSSFQYYPDDPENPVNKYKFALKADSQYYD
                     PCEESSKLSFQCLERNDYDRSKCQEYFDAYRECKKQWLTARRKNRQQWE"
     gene            <342349..>344268
                     /gene="TOM71"
                     /locus_tag="YHR117W"
                     /gene_synonym="TOM72"
                     /db_xref="GeneID:856517"
     mRNA            <342349..>344268
                     /gene="TOM71"
                     /locus_tag="YHR117W"
                     /gene_synonym="TOM72"
                     /product="protein channel TOM71"
                     /transcript_id="NM_001179247.1"
                     /db_xref="GI:296145495"
                     /db_xref="GeneID:856517"
     CDS             342349..344268
                     /gene="TOM71"
                     /locus_tag="YHR117W"
                     /gene_synonym="TOM72"
                     /note="Mitochondrial outer membrane protein; probable
                     minor component of the TOM (translocase of outer membrane)
                     complex responsible for recognition and import of
                     mitochondrially directed proteins; TOM71 has a paralog,
                     TOM70, that arose from the whole genome duplication"
                     /codon_start=1
                     /product="protein channel TOM71"
                     /protein_id="NP_011985.1"
                     /db_xref="GI:6321909"
                     /db_xref="SGD:S000001159"
                     /db_xref="GeneID:856517"
                     /translation="MAENSLLRFITKNKVAILATVSAGTAAVGAYVYYQQIKQQQQQQ
                     LKGTKDNRRQSEAFAGQNEDEADLKDDGSVVSGSNKRKKKKNKRKRNNKAKSGEGFDY
                     PSLPNGEPDIAQLKGLSPSQRQAYAVQLKNRGNHFFTAKNFNEAIKYYQYAIELDPNE
                     PVFYSNISACYISTGDLEKVIEFTTKALEIKPDHSKALLRRASANESLGNFTDAMFDL
                     SVLSLNGDFDGASIEPMLERNLNKQAMKVLNENLSKDEGRGSQVLPSNTSLASFFGIF
                     DSHLEVSSVNTSSNYDTAYALLSDALQRLYSATDEGYLVANDLLTKSTDMYHSLLSAN
                     TVDDPLRENAALALCYTGIFHFLKNNLLDAQVLLQESINLHPTPNSYIFLALTLADKE
                     NSQEFFKFFQKAVDLNPEYPPTYYHRGQMYFILQDYKNAKEDFQKAQSLNPENVYPYI
                     QLACLLYKQGKFTESEAFFNETKLKFPTLPEVPTFFAEILTDRGDFDTAIKQYDIAKR
                     LEEVQEKIHVGIGPLIGKATILARQSSQDPTQLDEEKFNAAIKLLTKACELDPRSEQA
                     KIGLAQLKLQMEKIDEAIELFEDSAILARTMDEKLQATTFAEAAKIQKRLRADPIISA
                     KMELTLARYRAKGML"
     gene            complement(<344321..>345628)
                     /gene="ORC6"
                     /locus_tag="YHR118C"
                     /db_xref="GeneID:856518"
     mRNA            complement(<344321..>345628)
                     /gene="ORC6"
                     /locus_tag="YHR118C"
                     /product="origin recognition complex subunit 6"
                     /transcript_id="NM_001179248.1"
                     /db_xref="GI:296145496"
                     /db_xref="GeneID:856518"
     CDS             complement(344321..345628)
                     /gene="ORC6"
                     /locus_tag="YHR118C"
                     /note="Subunit of the origin recognition complex (ORC);
                     ORC directs DNA replication by binding to replication
                     origins and is also involved in transcriptional silencing;
                     phosphorylated by Cdc28p; mutation in the human Orc6p is
                     linked to Meier-Gorlin syndrome"
                     /codon_start=1
                     /product="origin recognition complex subunit 6"
                     /protein_id="NP_011986.1"
                     /db_xref="GI:6321910"
                     /db_xref="SGD:S000001160"
                     /db_xref="GeneID:856518"
                     /translation="MSMQQVQHCVAEVLRLDPQEKPDWSSGYLKKLTNATSILYNTSL
                     NKVMLKQDEEVARCHICAYIASQKMNEKHMPDLCYYIDSIPLEPKKAKHLMNLFRQSL
                     SNSSPMKQFAWTPSPKKNKRSPVKNGGRFTSSDPKELRNQLFGTPTKVRKSQNNDSFV
                     IPELPPMQTNESPSITRRKLAFEEDEDEDEEEPGNDGLSLKSHSNKSITGTRNVDSDE
                     YENHESDPTSEEEPLGVQESRSGRTKQNKAVGKPQSELKTAKALRKRGRIPNSLLVKK
                     YCKMTTEEIIRLCNDFELPREVAYKIVDEYNINASRLVCPWQLVCGLVLNCTFIVFNE
                     RRRKDPRIDHFIVSKMCSLMLTSKVDDVIECVKLVKELIIGEKWFRDLQIRYDDFDGI
                     RYDEIIFRKLGSMLQTTNILVTDDQYNIWKKRIEMDLALTEPL"
     gene            <346043..>349285
                     /gene="SET1"
                     /locus_tag="YHR119W"
                     /gene_synonym="KMT2; YTX1"
                     /db_xref="GeneID:856519"
     mRNA            <346043..>349285
                     /gene="SET1"
                     /locus_tag="YHR119W"
                     /gene_synonym="KMT2; YTX1"
                     /product="histone methyltransferase SET1"
                     /transcript_id="NM_001179249.1"
                     /db_xref="GI:296145497"
                     /db_xref="GeneID:856519"
     CDS             346043..349285
                     /gene="SET1"
                     /locus_tag="YHR119W"
                     /gene_synonym="KMT2; YTX1"
                     /EC_number="2.1.1.43"
                     /note="Histone methyltransferase, subunit of the COMPASS
                     (Set1C) complex; COMPASS methylates histone H3K4;
                     Set1p-dependent H3K4 trimethylation recruits Nrd1p,
                     allowing efficient termination of snoRNAs and cryptic
                     unstable transcripts (CUTs) by Nrd1p-Nab3p-Sen1p pathway;
                     modulates histone acetylation levels in promoter proximal
                     regions to ensure efficient Nrd1p-dependent termination;
                     required in transcriptional silencing near telomeres and
                     at silent mating type loci; has a SET domain"
                     /codon_start=1
                     /product="histone methyltransferase SET1"
                     /protein_id="NP_011987.1"
                     /db_xref="GI:6321911"
                     /db_xref="SGD:S000001161"
                     /db_xref="GeneID:856519"
                     /translation="MSNYYRRAHASSGSYRQPQEQPQYSRSGHYQYSNGHSHQQYSSQ
                     YNQRRRYNHNDGTRRRYNDDRPHSSNNASTRQYYATNNSQSGPYVNKKSDISSRRGMS
                     QSRYSNSNVHNTLASSSGSLPTESALLLQQRPPSVLRYNTDNLKSKFHYFDPIKGEFF
                     NKDKMLSWKATDKEFSETGYYVVKELQDGQFKFKIKHRHPEIKASDPRNENGIMTSGK
                     VATHRKCRNSLILLPRISYDRYSLGPPPSCEIVVYPAQDSTTTNIQDISIKNYFKKYG
                     EISHFEAFNDPNSALPLHVYLIKYASSDGKINDAAKAAFSAVRKHESSGCFIMGFKFE
                     VILNKHSILNNIISKFVEINVKKLQKLQENLKKAKEKEAENEKAKELQGKDITLPKEP
                     KVDTLSHSSGSEKRIPYDLLGVVNNRPVLHVSKIFVAKHRFCVEDFKYKLRGYRCAKF
                     IDHPTGIYIIFNDIAHAQTCSNAESGNLTIMSRSRRIPILIKFHLILPRFQNRTRFNK
                     SSSSSNSTNVPIKYESKEEFIEATAKQILKDLEKTLHVDIKKRLIGPTVFDALDHANF
                     PELLAKRELKEKEKRQQIASKIAEDELKRKEEAKRDFDLFGLYGGYAKSNKRNLKRHN
                     SLALDHTSLKRKKLSNGIKPMAHLLNEETDSKETTPLNDEGITRVSKEHDEEDENMTS
                     SSSEEEEEEAPDKKFKSESEPTTPESDHLHGIKPLVPDQNGSSDVLDASSMYKPTATE
                     IPEPVYPPEEYDLKYSQTLSSMDLQNAIKDEEDMLILKQLLSTYTPTVTPETSAALEY
                     KIWQSRRKVLEEEKASDWQIELNGTLFDSELQPGSSFKAEGFRKIADKLKINYLPHRR
                     RVHQPLNTVNIHNERNEYTPELCQREESSNKEPSDSVPQEVSSSRDNRASNRRFQQDI
                     EAQKAAIGTESELLSLNQLNKRKKPVMFARSAIHNWGLYALDSIAAKEMIIEYVGERI
                     RQPVAEMREKRYLKNGIGSSYLFRVDENTVIDATKKGGIARFINHCCDPNCTAKIIKV
                     GGRRRIVIYALRDIAASEELTYDYKFEREKDDEERLPCLCGAPNCKGFLN"
     gene            <349574..>352453
                     /gene="MSH1"
                     /locus_tag="YHR120W"
                     /db_xref="GeneID:856520"
     mRNA            <349574..>352453
                     /gene="MSH1"
                     /locus_tag="YHR120W"
                     /product="mismatch repair ATPase MSH1"
                     /transcript_id="NM_001179250.1"
                     /db_xref="GI:296145498"
                     /db_xref="GeneID:856520"
     CDS             349574..352453
                     /gene="MSH1"
                     /locus_tag="YHR120W"
                     /note="DNA-binding protein of the mitochondria; involved
                     in repair of mitochondrial DNA; has ATPase activity and
                     binds to DNA mismatches; has homology to E. coli MutS;
                     transcription is induced during meiosis"
                     /codon_start=1
                     /product="mismatch repair ATPase MSH1"
                     /protein_id="NP_011988.1"
                     /db_xref="GI:6321912"
                     /db_xref="SGD:S000001162"
                     /db_xref="GeneID:856520"
                     /translation="MKHFFRLPTAFRPISRVSLRYSSTDTAQPKISKLKISFNKISES
                     NSEKKDNLGSIDTRNCLSTQQDDKLSSTEPSKASLPPSLQYVRDLMDLYKDHVVLTQM
                     GSFYELYFEQAIRYAPELNISLTNRAYSHGKVPFAGFPVHQLSRHLKMLVNNCGYSVT
                     IAEQFKKKDVADNEANKFYRRVTRIVTPGTFIDEAFENLRENTYLLNIEFPENCMSQV
                     ADTSLKVGICWCDVSTGEIFVQQVYLRDLVSAITRIQPKEILLDERLLEFHIESGTWY
                     PELVELKKFFIKYQKMPSQHRTIESFYGLFNLGGKEATERQLKIQFQTFTQKELAALR
                     NTLIYVSNHLPDFSINFQIPQRQLATAIMQIDSRTSTALELHSTVRDNNKKGSLLSSI
                     RRTVTPSGTRLLSQWLSGPSLDLKEIKKRQKIVAFFKDNRDITETLRTMLKKVNDLSR
                     ILQKFSFGRGEALELIQMARSLEVSREIRKYLLNNTSLMKATLKSQITQLTESLNFEK
                     NLIDDILKFLNEEELAKSQDAKQNADVTRMLDIDVKDKKESNKDEIFELRDFIVNPSF
                     NTKLRKLHDTYQGVWQKKTEYNALLKGFFVGDLGAKTFTLKERQNGEYALHVTGTASS
                     LKKIDELISKSTEYHGSCFHILQKSSQTRWLSHKIWTDLGHELELLNLKIRNEEANII
                     DLFKRKFIDRSNEVRQVATTLGYLDTLSSFAVLANERNLVCPKVDESNKLEVVNGRHL
                     MVEEGLSARSLETFTANNCELAKDNLWVITGPNMGGKSTFLRQNAIIVILAQIGCFVP
                     CSKARVGIVDKLFSRVGSADDLYNEMSTFMVEMIETSFILQGATERSLAILDEIGRGT
                     SGKEGISIAYATLKYLLENNQCRTLFATHFGQELKQIIDNKCSKGMSEKVKFYQSGIT
                     DLGGNNFCYNHKLKPGICTKSDAIRVAELAGFPMEALKEAREILG"
     gene            <352756..>353319
                     /gene="LSM12"
                     /locus_tag="YHR121W"
                     /db_xref="GeneID:856521"
     mRNA            <352756..>353319
                     /gene="LSM12"
                     /locus_tag="YHR121W"
                     /product="Lsm12p"
                     /transcript_id="NM_001179251.1"
                     /db_xref="GI:296145499"
                     /db_xref="GeneID:856521"
     CDS             352756..353319
                     /gene="LSM12"
                     /locus_tag="YHR121W"
                     /note="hypothetical protein that may function in RNA
                     processing; interacts with Pbp1p and Pbp4p and associates
                     with ribosomes; contains an RNA-binding LSM domain and an
                     AD domain; GFP-fusion protein is induced by the
                     DNA-damaging agent MMS; relative distribution to the
                     nucleus increases upon DNA replication stress"
                     /codon_start=1
                     /product="Lsm12p"
                     /protein_id="NP_011989.1"
                     /db_xref="GI:6321913"
                     /db_xref="SGD:S000001163"
                     /db_xref="GeneID:856521"
                     /translation="MSVSLEQTLGFRIKVTNVLDVVTEGRLYSFNSSNNTLTIQTTKK
                     NQSPQNFKVIKCTFIKHLEVIGDKPSFNSFKKQQIKPSYVNVERVEKLLKESVIASKK
                     KELLRGKGVSAEGQFIFDQIFKTIGDTKWVAKDIIILDDVKVQPPYKVEDIKVLHEGS
                     NQSITLIQRIVERSWEQLEQDDGRKGG"
     gene            <353625..>354320
                     /gene="CIA2"
                     /locus_tag="YHR122W"
                     /db_xref="GeneID:856522"
     mRNA            <353625..>354320
                     /gene="CIA2"
                     /locus_tag="YHR122W"
                     /product="Cia2p"
                     /transcript_id="NM_001179252.1"
                     /db_xref="GI:296145500"
                     /db_xref="GeneID:856522"
     CDS             353625..354320
                     /gene="CIA2"
                     /locus_tag="YHR122W"
                     /note="Component of cytosolic iron-sulfur protein assembly
                     (CIA) machinery; acts at a late step of Fe-S cluster
                     assembly; forms the CIA targeting complex with Cia1p and
                     Met18p that directs Fe-S cluster incorporation into a
                     subset of proteins involved in methionine biosynthesis,
                     DNA replication and repair, transcription, and telomere
                     maintenance; ortholog of human FAM96B"
                     /codon_start=1
                     /product="Cia2p"
                     /protein_id="NP_011990.1"
                     /db_xref="GI:6321914"
                     /db_xref="SGD:S000001164"
                     /db_xref="GeneID:856522"
                     /translation="MSEFLNENPDILEENQLPTRKEDSTKDLLLGGFSNEATLERRSL
                     LLKIDHSLKSQVLQDIEVLDKLLSIRIPPELTSDEDSLPAESEDESVAGGGKEEEEPD
                     LIDAQEIYDLIAHISDPEHPLSLGQLSVVNLEDIDVHDSGNQNEMAEVVIKITPTITH
                     CSLATLIGLGIRVRLERSLPPRFRITILLKKGTHDSENQVNKQLNDKERVAAACENEQ
                     LLGVVSKMLVTCK"
     gene            <354815..>356081
                     /gene="EPT1"
                     /locus_tag="YHR123W"
                     /db_xref="GeneID:856523"
     mRNA            join(<354815..354864,354956..>356081)
                     /gene="EPT1"
                     /locus_tag="YHR123W"
                     /product="bifunctional diacylglycerol
                     cholinephosphotransferase/ethanolaminephosphotransferase"
                     /transcript_id="NM_001179253.1"
                     /db_xref="GI:296145501"
                     /db_xref="GeneID:856523"
     CDS             join(354815..354864,354956..356081)
                     /gene="EPT1"
                     /locus_tag="YHR123W"
                     /EC_number="2.7.8.2"
                     /EC_number="2.7.8.1"
                     /note="sn-1,2-diacylglycerol ethanolamine- and
                     cholinephosphotranferase; not essential for viability;
                     EPT1 has a paralog, CPT1, that arose from the whole genome
                     duplication"
                     /codon_start=1
                     /product="bifunctional diacylglycerol
                     cholinephosphotransferase/ethanolaminephosphotransferase"
                     /protein_id="NP_011991.1"
                     /db_xref="GI:6321915"
                     /db_xref="SGD:S000001165"
                     /db_xref="GeneID:856523"
                     /translation="MGYFVPDSHIENLKSYKYQSEDRSLVSKYFLKPFWQRFCHIFPT
                     WMAPNIITLSGFAFIVINVLTVFYYDPNLNTDTPRWTYFSYALGVFLYQTFDGCDGVH
                     ARRINQSGPLGELFDHSIDAINSTLSIFIFASETGMGFSYNLMLSQFAMLTNFYLSTW
                     EEYHTHTLYLSEFSGPVEGILIVCVSLILTGIYGKQVIWHTYLFTITVGDKVIDVDTL
                     DIVFSLAVFGLVMNALSAKRNVDKYYRNSTSSANNITQIEQDSAIKGLLPFFAYYASI
                     ALLVWMQPSFITLSFILSVGFTGAFTVGRIIVCHLTKQSFPMFNAPMLIPLCQIVLYK
                     ICLSLWGIESNKIVFALSWLGFGLSLGVHIMFMNDIIHEFTEYLDVYALSIKRSKLT"
     gene            <356561..>358444
                     /gene="NDT80"
                     /locus_tag="YHR124W"
                     /db_xref="GeneID:856524"
     mRNA            <356561..>358444
                     /gene="NDT80"
                     /locus_tag="YHR124W"
                     /product="transcription factor NDT80"
                     /transcript_id="NM_001179254.1"
                     /db_xref="GI:296145502"
                     /db_xref="GeneID:856524"
     CDS             356561..358444
                     /gene="NDT80"
                     /locus_tag="YHR124W"
                     /note="Meiosis-specific transcription factor; required for
                     exit from pachytene and for full meiotic recombination;
                     activates middle sporulation genes; competes with Sum1p
                     for binding to promoters containing middle sporulation
                     elements (MSE)"
                     /codon_start=1
                     /product="transcription factor NDT80"
                     /protein_id="NP_011992.1"
                     /db_xref="GI:6321916"
                     /db_xref="SGD:S000001166"
                     /db_xref="GeneID:856524"
                     /translation="MNEMENTDPVLQDDLVSKYERELSTEQEEDTPVILTQLNEDGTT
                     SNYFDKRKLKIAPRSTLQFKVGPPFELVRDYCPVVESHTGRTLDLRIIPRIDRGFDHI
                     DEEWVGYKRNYFTLVSTFETANCDLDTFLKSSFDLLVEDSSVESRLRVQYFAIKIKAK
                     NDDDDTEINLVQHTAKRDKGPQFCPSVCPLVPSPLPKHQIIREASNVRNITKMKKYDS
                     TFYLHRDHVNYEEYGVDSLLFSYPEDSIQKVARYERVQFASSISVKKPSQQNKHFSLH
                     VILGAVVDPDTFHGENPGIPYDELALKNGSKGMFVYLQEMKTPPLIIRGRSPSNYASS
                     QRITVRTPSSVNSSQNSTKRKMPSMAQPLNESCLNARPSKRRSKVALGAPNSGASISP
                     IKSRQSTPMEASKENEDPFFRPNKRVETLEHIQNKLGALKNQCPDSSLKYPSSSSRGM
                     EGCLEKEDLVYSSSFSVNMKQIELKPARSFEHENIFKVGSLAFKKINELPHENYDITI
                     EKKSMEQNYLRPEIGSRSECKTSYGNELSLSNISFSILPNSAENFHLETALFPATEED
                     VPRTFSRILETGSFQNYYQKMDAENADRVYSKGVKLIASGTLPSGIFNREELFEEDSF
                     YKY"
     gene            complement(358478..358569)
                     /locus_tag="tF(GAA)H2"
                     /db_xref="GeneID:856525"
     tRNA            complement(join(358478..358513,358533..358569))
                     /locus_tag="tF(GAA)H2"
                     /product="tRNA-Phe"
                     /note="Phenylalanine tRNA (tRNA-Phe), predicted by
                     tRNAscan-SE analysis; tF(GAA)H2"
                     /db_xref="SGD:S000006567"
                     /db_xref="GeneID:856525"
     LTR             complement(358672..358850)
                     /note="Ty1 LTR"
                     /db_xref="SGD:S000006996"
     LTR             complement(358850..359067)
                     /note="Ty4 LTR"
                     /db_xref="SGD:S000007005"
     LTR             359079..359372
                     /note="Ty1 LTR"
                     /db_xref="SGD:S000007008"
     gene            complement(<359702..>360181)
                     /gene="ANS1"
                     /locus_tag="YHR126C"
                     /db_xref="GeneID:856527"
     mRNA            complement(<359702..>360181)
                     /gene="ANS1"
                     /locus_tag="YHR126C"
                     /product="Ans1p"
                     /transcript_id="NM_001179256.1"
                     /db_xref="GI:296145503"
                     /db_xref="GeneID:856527"
     CDS             complement(359702..360181)
                     /gene="ANS1"
                     /locus_tag="YHR126C"
                     /note="Putative GPI protein; transcription dependent upon
                     Azf1p"
                     /codon_start=1
                     /product="Ans1p"
                     /protein_id="NP_011994.1"
                     /db_xref="GI:6321918"
                     /db_xref="SGD:S000001168"
                     /db_xref="GeneID:856527"
                     /translation="MKCTLVSTLFAITNILVAHAQVSNSSDTLDVQFANSTNSYIEGK
                     FNSTDEAFNSSASWSLAAQQKKISNAAVYDVGGWNGSLYRSNRSAVADHQPGKKQDAA
                     ISQISDGQIQATASGPETTAATTPSSTANVSVYEGAGMKVESKNMGYIVGVAALLFL"
     gene            <360913..>361644
                     /locus_tag="YHR127W"
                     /db_xref="GeneID:856528"
     mRNA            <360913..>361644
                     /locus_tag="YHR127W"
                     /product="hypothetical protein"
                     /transcript_id="NM_001179257.1"
                     /db_xref="GI:296145504"
                     /db_xref="GeneID:856528"
     CDS             360913..361644
                     /locus_tag="YHR127W"
                     /note="hypothetical protein; localizes to the nucleus;
                     required for asymmetric localization of Kar9p during
                     mitosis"
                     /codon_start=1
                     /product="hypothetical protein"
                     /protein_id="NP_011995.1"
                     /db_xref="GI:6321919"
                     /db_xref="SGD:S000001169"
                     /db_xref="GeneID:856528"
                     /translation="MARNRTTSKKNVQSKRLIDRVVPMDKIKKVGVAKKKTVEHTKEG
                     FSVVNGKLVSSNDVGVLLREAQGAIDKRTNVSQRNRKKGIKNNRPHKDINSSPDWGNA
                     HRGTDWQSEKANGMNRAKNSRNFTTNIKLQRQHFGEEIQGGSQLVISTNSDASDKLLM
                     LFNLTLGVNQENLKNVLENISQVQIAQIRVRDLPSGSATAKVRLAYPTTQSLEKVRKL
                     FHGALVDGRRIQVVIASDESSHLSY"
     gene            <362115..>362765
                     /gene="FUR1"
                     /locus_tag="YHR128W"
                     /db_xref="GeneID:856529"
     mRNA            <362115..>362765
                     /gene="FUR1"
                     /locus_tag="YHR128W"
                     /product="uracil phosphoribosyltransferase"
                     /transcript_id="NM_001179258.1"
                     /db_xref="GI:296145505"
                     /db_xref="GeneID:856529"
     CDS             362115..362765
                     /gene="FUR1"
                     /locus_tag="YHR128W"
                     /EC_number="2.4.2.9"
                     /note="Uracil phosphoribosyltransferase; synthesizes UMP
                     from uracil; involved in the pyrimidine salvage pathway"
                     /codon_start=1
                     /product="uracil phosphoribosyltransferase"
                     /protein_id="NP_011996.2"
                     /db_xref="GI:37362660"
                     /db_xref="SGD:S000001170"
                     /db_xref="GeneID:856529"
                     /translation="MSSEPFKNVYLLPQTNQLLGLYTIIRNKNTTRPDFIFYSDRIIR
                     LLVEEGLNHLPVQKQIVETDTNENFEGVSFMGKICGVSIVRAGESMEQGLRDCCRSVR
                     IGKILIQRDEETALPKLFYEKLPEDISERYVFLLDPMLATGGSAIMATEVLIKRGVKP
                     ERIYFLNLICSKEGIEKYHAAFPEVRIVTGALDRGLDENKYLVPGLGDFGDRYYCV"
     gene            complement(<362999..>364153)
                     /gene="ARP1"
                     /locus_tag="YHR129C"
                     /gene_synonym="ACT5"
                     /db_xref="GeneID:856530"
     mRNA            complement(<362999..>364153)
                     /gene="ARP1"
                     /locus_tag="YHR129C"
                     /gene_synonym="ACT5"
                     /product="actin-related protein 1"
                     /transcript_id="NM_001179259.1"
                     /db_xref="GI:296145506"
                     /db_xref="GeneID:856530"
     CDS             complement(362999..364153)
                     /gene="ARP1"
                     /locus_tag="YHR129C"
                     /gene_synonym="ACT5"
                     /note="Actin-related protein of the dynactin complex;
                     required for spindle orientation and nuclear migration;
                     forms actin-like short filament composed of 9 or 10 Arp1p
                     monomers; putative ortholog of mammalian centractin"
                     /codon_start=1
                     /product="actin-related protein 1"
                     /protein_id="NP_011997.1"
                     /db_xref="GI:6321921"
                     /db_xref="SGD:S000001171"
                     /db_xref="GeneID:856530"
                     /translation="MDQLSDSYALYNQPVVIDNGSGIIKAGFSGEERPKALEYCLVGN
                     TKYDKVMLEGLQGDTFIGNNAQKLRGLLKLRYPIKHGVVEDWDSMELIWSYVLNEVLQ
                     LQNIGEHPLLITEAPMNPLKNREQMAQVLFETFDVSALYVSNPAVLSLYASGRTTGCV
                     VDCGEGYCSTVPIYDGFALPASMMRMDIGGADITEQLQFQLRKSAGVSLFSSSEREIV
                     RTMKEKVCYLAKNIKKEEEKYLQGTQDLISTFKLPDGRCIEVGNDRYRAPEILFSPQI
                     IGLGYDGLSDMCMQSIWKVDLDLRKPLLSSIILSGGTTTLKGFGDRMLWDLEALTKGT
                     SKIKIIAPSERKYTTWIGGSILTGLSTFQRLWTKKSDWLEDSTRVYSNLM"
     gene            complement(<365340..>367892)
                     /locus_tag="YHR131C"
                     /db_xref="GeneID:856532"
     mRNA            complement(<365340..>367892)
                     /locus_tag="YHR131C"
                     /product="hypothetical protein"
                     /transcript_id="NM_001179261.1"
                     /db_xref="GI:296145507"
                     /db_xref="GeneID:856532"
     CDS             complement(365340..367892)
                     /locus_tag="YHR131C"
                     /note="hypothetical protein; GFP-fusion protein localizes
                     to the cytoplasm; overexpression causes cell cycle delay
                     or arrest; contains a PH domain and binds
                     phosphatidylinositols and other lipids in a large-scale
                     study; YHR131C has a paralog, YNL144C, that arose from the
                     whole genome duplication"
                     /codon_start=1
                     /product="hypothetical protein"
                     /protein_id="NP_011999.2"
                     /db_xref="GI:50882584"
                     /db_xref="SGD:S000001173"
                     /db_xref="GeneID:856532"
                     /translation="MALPIEGKLSMANNRIERLKSPSSSSTCSMDEVLITSSNNSSSI
                     CLETMRQLPREGVSGQINIIKETAASSSSHAALFIKQDLYEHIDPLPAYPPSYDLVNP
                     NKEVRFPIFGDTAPCPKSSLPPLYAPAVYELTLISLKLERLSPYEISSNRSWRNFIIE
                     INSTQLNFYHIDESLTKHIRNYSSGETKSEKEDRIHSDLVHRSDQSQHLHHRLFTLPT
                     RSASEFKKADQERISYRVKRDRSRYLTDEALYKSFTLQNARFGIPTDYTKKSFVLRMS
                     CESEQFLLRFSHIDDMIDWSMYLSIGISVSLDLEVREYPDYRIVPRRRRRRRRRRRRR
                     RHTHRSESSMGSFSQRFIRSNSRPDLIQRYSTGSSTNNNTTIRERSNTFTAGLLDHYC
                     TGLSKTPTEALISSAASGESSDNSTLGSTRSLSGCSASRSIASRSLKFKIKNFFRPKN
                     SSRTEKLHRLRSNSSNLNSVIETEEDDEHHESSGGDHPEPGVPVNTTIKVERPMHRNR
                     AISMPQRQSLRRAISEEVVPIKFPNSTVGESVHSPSPIEHLSVDGCEIMLQSQNAVMK
                     EELRSVASNLVANERDEASIRPKPQSSSIYLSGLAPNGESATDLSQSSRSLCLTNRDA
                     EINDDESATETDEDENDGETDEYAGDDTNDDTDDSNIGYAYGSESDYSCLIEERIRNR
                     RRASSTLSCFSNIPYGTDDIKWKPAIKEISRRRYLRDSLKCIKPFLDSNDCLGKVIYI
                     PVSGPTFETSNKIHFSNRQSLQKQKNHFLKGFIVGPTALIELNCKNKNAIVGTTKDAE
                     DHGEDDGDGDDGEDDDDDDDDDDDDDDDEDDDDDDDDDDDDDDDDDDGQITA"
     gene            complement(<368502..>369794)
                     /gene="ECM14"
                     /locus_tag="YHR132C"
                     /db_xref="GeneID:856533"
     mRNA            complement(<368502..>369794)
                     /gene="ECM14"
                     /locus_tag="YHR132C"
                     /product="Ecm14p"
                     /transcript_id="NM_001179262.1"
                     /db_xref="GI:296145508"
                     /db_xref="GeneID:856533"
     CDS             complement(368502..369794)
                     /gene="ECM14"
                     /locus_tag="YHR132C"
                     /EC_number="3.4.17.-"
                     /note="Putative metalloprotease with similarity to zinc
                     carboxypeptidases; required for normal cell wall assembly"
                     /codon_start=1
                     /product="Ecm14p"
                     /protein_id="NP_012000.1"
                     /db_xref="GI:6321924"
                     /db_xref="SGD:S000001174"
                     /db_xref="GeneID:856533"
                     /translation="MLHMNSLWGCFLFVLLAVTGAVQGLQEDYSEYAVYRFTSDNYST
                     LVRDVIAPLTDDYDVWTRSNNFIDIKLPKEIGEQINDGQVIIDNMNELIQNTLPTSQM
                     MAREQAVFENDYDFFFNEYRDLDTIYMWLDLLERSFPSLVAVEHLGRTFEGRELKALH
                     ISGNKPESNPEKKTIVITGGIHAREWISVSTVCWALYQLLNRYGSSKKETKYLDDLDF
                     LVIPVFNPDGYAYTWSHDRLWRKNRQRTHVPQCLGIDIDHSFGFQWEKAHTHACSEEY
                     SGETPFEAWEASAWYKYINETKGDYKIYGYIDMHSYSQEILYPYAYSCDALPRDLENL
                     LELSYGLSKAIRSKSGRNYDVISACKDRGSDIFPGLGAGSALDFMYHHRAHWAFQLKL
                     RDTGNHGFLLPPENIKPVGKETYAALKYFCDFLLDPEI"
     gene            <370054..>370449
                     /gene="IGO2"
                     /locus_tag="YHR132W-A"
                     /db_xref="GeneID:856534"
     mRNA            <370054..>370449
                     /gene="IGO2"
                     /locus_tag="YHR132W-A"
                     /product="Igo2p"
                     /transcript_id="NM_001184441.1"
                     /db_xref="GI:296145509"
                     /db_xref="GeneID:856534"
     CDS             370054..370449
                     /gene="IGO2"
                     /locus_tag="YHR132W-A"
                     /note="Protein required for initiation of G0 program;
                     prevents degradation of nutrient-regulated mRNAs via the
                     5'-3' mRNA decay pathway; phosphorylated by Rim15p; GFP
                     protein localizes to the cytoplasm and nucleus; IGO2 has a
                     paralog, IGO1, that arose from the whole genome
                     duplication"
                     /codon_start=1
                     /product="Igo2p"
                     /protein_id="NP_036194.1"
                     /db_xref="GI:6862571"
                     /db_xref="SGD:S000007496"
                     /db_xref="GeneID:856534"
                     /translation="MSEDLSPTSSRVDLSNPHGFTKEGVDLSKLSPQELKLYKMYGKL
                     PSKKDLLRHKMQDRQYFDSGDYALKKAGVIKSDDVIVNNSSNNLPVTNPSGLRESIIR
                     RRMSSSSGGDSISRQGSISSGPPPRSPNK"
     gene            complement(<370722..>371597)
                     /gene="NSG1"
                     /locus_tag="YHR133C"
                     /db_xref="GeneID:856535"
     mRNA            complement(<370722..>371597)
                     /gene="NSG1"
                     /locus_tag="YHR133C"
                     /product="Nsg1p"
                     /transcript_id="NM_001179263.1"
                     /db_xref="GI:296145510"
                     /db_xref="GeneID:856535"
     CDS             complement(370722..371597)
                     /gene="NSG1"
                     /locus_tag="YHR133C"
                     /note="Protein involved in regulation of sterol
                     biosynthesis; specifically stabilizes Hmg2p, one of two
                     HMG-CoA isoenzymes that catalyze the rate-limiting step in
                     sterol biosynthesis; forms foci at the nuclear periphery
                     upon DNA replication stress; relocalizes to the cytosol in
                     response to hypoxia; homolog of mammalian INSIG proteins;
                     NSG1 has a paralog, NSG2, that arose from the whole genome
                     duplication"
                     /codon_start=1
                     /product="Nsg1p"
                     /protein_id="NP_012001.1"
                     /db_xref="GI:6321925"
                     /db_xref="SGD:S000001175"
                     /db_xref="GeneID:856535"
                     /translation="MGKKKSKNQLNTGGVPNGVHNTKKEAALPPLGNKLGSASFTAIN
                     TLTKPALFSFYDDDITKNEGNVYDKALLSNASQLEMVPPSATARHERSLYAKIINTIA
                     AFFILFIAGILFPMISECLFDNDQLAKGDIVSFLKHGIEIKNKIVAEPDMVPDWAVFG
                     TEGVIFGSIVPFIDSFVRYQHQPKTRSSVYKNTLGSFIRCANTLLGLIFGIRKLEWSS
                     SLQAAGAWSLLNIVLWLFFDGTLTVFFPGLVIGALSAFTCSQCFSQLSLALYFIDFYF
                     FGFLMFSKLGRYLFN"
     gene            <371749..>372558
                     /gene="WSS1"
                     /locus_tag="YHR134W"
                     /db_xref="GeneID:856536"
     mRNA            <371749..>372558
                     /gene="WSS1"
                     /locus_tag="YHR134W"
                     /product="Wss1p"
                     /transcript_id="NM_001179264.1"
                     /db_xref="GI:296145511"
                     /db_xref="GeneID:856536"
     CDS             371749..372558
                     /gene="WSS1"
                     /locus_tag="YHR134W"
                     /EC_number="3.4.24.-"
                     /note="Metalloprotease involved in DNA repair, removes
                     DNA-protein crosslinks at stalled replication forks during
                     replication of damaged DNA; sumoylated protein localizing
                     to the nuclear periphery of mother cells; localizes to a
                     single spot on the nuclear periphery of mother cells but
                     not daughters; interacts genetically with SMT3; activated
                     by DNA binding"
                     /codon_start=1
                     /product="Wss1p"
                     /protein_id="NP_012002.1"
                     /db_xref="GI:6321926"
                     /db_xref="SGD:S000001176"
                     /db_xref="GeneID:856536"
                     /translation="MKTEGIKSPSAKYHDMAGSQRIPHKNPHIQKVAVLQSKPNKEDA
                     LNLIKEIAHKVSYLMKENHFKVTNLVEFYPRDQRLLGMNVNHGSKIMLRLRCSTDEFQ
                     FLPMECIMGTMLHELTHNLFGPHDKKFYNKLDELIGRQWVIEQRGLYDTFLGNGQRLG
                     GRANLRSNRYPMTGISTNTGIVRKRGKGVKLGSLHPEGISSIDRGNSPRELAAFAAER
                     RYRDDRWCGETKNNKDQIISDNISSSLEVVILDDDDEVLPGDTLIEVIDLT"
     gene            complement(<372694..>374310)
                     /gene="YCK1"
                     /locus_tag="YHR135C"
                     /gene_synonym="CKI2"
                     /db_xref="GeneID:856537"
     mRNA            complement(<372694..>374310)
                     /gene="YCK1"
                     /locus_tag="YHR135C"
                     /gene_synonym="CKI2"
                     /product="serine/threonine protein kinase YCK1"
                     /transcript_id="NM_001179265.1"
                     /db_xref="GI:296145512"
                     /db_xref="GeneID:856537"
     CDS             complement(372694..374310)
                     /gene="YCK1"
                     /locus_tag="YHR135C"
                     /gene_synonym="CKI2"
                     /EC_number="2.7.11.1"
                     /note="Palmitoylated plasma membrane-bound casein kinase I
                     (CK1) isoform; shares redundant functions with Yck2p in
                     morphogenesis, proper septin assembly, endocytic
                     trafficking, and glucose sensing; stabilized by Sod1p
                     binding in the presence of glucose and oxygen, causing
                     glucose repression of respiratory metabolism; YCK1 has a
                     paralog, YCK2, that arose from the whole genome
                     duplication"
                     /codon_start=1
                     /product="serine/threonine protein kinase YCK1"
                     /protein_id="NP_012003.1"
                     /db_xref="GI:6321927"
                     /db_xref="SGD:S000001177"
                     /db_xref="GeneID:856537"
                     /translation="MSMPIASTTLAVNNLTNINGNANFNVQANKQLHHQAVDSPARSS
                     MTATTAANSNSNSSRDDSTIVGLHYKIGKKIGEGSFGVLFEGTNMINGVPVAIKFEPR
                     KTEAPQLRDEYKTYKILNGTPNIPYAYYFGQEGLHNILVIDLLGPSLEDLFDWCGRKF
                     SVKTVVQVAVQMITLIEDLHAHDLIYRDIKPDNFLIGRPGQPDANNIHLIDFGMAKQY
                     RDPKTKQHIPYREKKSLSGTARYMSINTHLGREQSRRDDMEALGHVFFYFLRGHLPWQ
                     GLKAPNNKQKYEKIGEKKRSTNVYDLAQGLPVQFGRYLEIVRSLSFEECPDYEGYRKL
                     LLSVLDDLGETADGQYDWMKLNDGRGWDLNINKKPNLHGYGHPNPPNEKSRKHRNKQL
                     QMQQLQMQQLQQQQQQQQYAQKTEADMRNSQYKPKLDPTSYEAYQHQTQQKYLQEQQK
                     RQQQQKLQEQQLQEQQLQQQQQQQQQLRATGQPPSQPQAQTQSQQFGARYQPQQQPSA
                     ALRTPEQHPNDDNSSLAASHKGFFQKLGCC"
     gene            complement(<374654..>375100)
                     /gene="SPL2"
                     /locus_tag="YHR136C"
                     /db_xref="GeneID:856538"
     mRNA            complement(<374654..>375100)
                     /gene="SPL2"
                     /locus_tag="YHR136C"
                     /product="Spl2p"
                     /transcript_id="NM_001179266.1"
                     /db_xref="GI:296145513"
                     /db_xref="GeneID:856538"
     CDS             complement(374654..375100)
                     /gene="SPL2"
                     /locus_tag="YHR136C"
                     /note="Protein with similarity to cyclin-dependent kinase
                     inhibitors; downregulates low-affinity phosphate transport
                     during phosphate limitation by targeting Pho87p to the
                     vacuole; upstream region harbors putative hypoxia response
                     element (HRE) cluster; overproduction suppresses a plc1
                     null mutation; promoter shows an increase in Snf2p
                     occupancy after heat shock; GFP-fusion protein localizes
                     to the cytoplasm"
                     /codon_start=1
                     /product="Spl2p"
                     /protein_id="NP_012004.1"
                     /db_xref="GI:6321928"
                     /db_xref="SGD:S000001178"
                     /db_xref="GeneID:856538"
                     /translation="MGTYTPLIYNIYNVHIWVFTESQGQIGQMSPRGKMETAVSQGQH
                     KQLKDGHQHKGRKLSEEIASLLRLKECRRLNPASYYTPRRTSQSQSLSGSTFKEYNEY
                     INEKDSSRAQRQNAAAVLSKLAHDFWENDCVIDEDIFEDSSDEEQS"
     gene            <375709..>377250
                     /gene="ARO9"
                     /locus_tag="YHR137W"
                     /db_xref="GeneID:856539"
     mRNA            <375709..>377250
                     /gene="ARO9"
                     /locus_tag="YHR137W"
                     /product="aromatic-amino-acid:2-oxoglutarate transaminase"
                     /transcript_id="NM_001179267.1"
                     /db_xref="GI:296145514"
                     /db_xref="GeneID:856539"
     CDS             375709..377250
                     /gene="ARO9"
                     /locus_tag="YHR137W"
                     /EC_number="2.6.1.7"
                     /EC_number="2.6.1.57"
                     /note="Aromatic aminotransferase II; catalyzes the first
                     step of tryptophan, phenylalanine, and tyrosine
                     catabolism"
                     /codon_start=1
                     /product="aromatic-amino-acid:2-oxoglutarate transaminase"
                     /protein_id="NP_012005.1"
                     /db_xref="GI:6321929"
                     /db_xref="SGD:S000001179"
                     /db_xref="GeneID:856539"
                     /translation="MTAGSAPPVDYTSLKKNFQPFLSRRVENRSLKSFWDASDISDDV
                     IELAGGMPNERFFPIESMDLKISKVPFNDNPKWHNSFTTAHLDLGSPSELPIARSFQY
                     AETKGLPPLLHFVKDFVSRINRPAFSDETESNWDVILSGGSNDSMFKVFETICDESTT
                     VMIEEFTFTPAMSNVEATGAKVIPIKMNLTFDRESQGIDVEYLTQLLDNWSTGPYKDL
                     NKPRVLYTIATGQNPTGMSVPQWKREKIYQLAQRHDFLIVEDDPYGYLYFPSYNPQEP
                     LENPYHSSDLTTERYLNDFLMKSFLTLDTDARVIRLETFSKIFAPGLRLSFIVANKFL
                     LQKILDLADITTRAPSGTSQAIVYSTIKAMAESNLSSSLSMKEAMFEGWIRWIMQIAS
                     KYNHRKNLTLKALYETESYQAGQFTVMEPSAGMFIIIKINWGNFDRPDDLPQQMDILD
                     KFLLKNGVKVVLGYKMAVCPNYSKQNSDFLRLTIAYARDDDQLIEASKRIGSGIKEFF
                     DNYKS"
     gene            complement(<377355..>377699)
                     /locus_tag="YHR138C"
                     /db_xref="GeneID:856540"
     mRNA            complement(<377355..>377699)
                     /locus_tag="YHR138C"
                     /product="hypothetical protein"
                     /transcript_id="NM_001179268.1"
                     /db_xref="GI:296145515"
                     /db_xref="GeneID:856540"
     CDS             complement(377355..377699)
                     /locus_tag="YHR138C"
                     /note="hypothetical protein; similar to Pbi2p; double null
                     mutant lacking Pbi2p and Yhr138cp exhibits highly
                     fragmented vacuoles; protein abundance increases in
                     response to DNA replication stress"
                     /codon_start=1
                     /product="hypothetical protein"
                     /protein_id="NP_012006.1"
                     /db_xref="GI:6321930"
                     /db_xref="SGD:S000001180"
                     /db_xref="GeneID:856540"
                     /translation="MKASYLVLIFISIFSMAQASSLSSYIVTFPKTDNMATDQNSIIE
                     DVKKYVVDIGGKITHEYSLIKGFTVDLPDSDQILDGLKERLSYIESEYGAKCNLEKDS
                     EVHALNRDHLVA"
     gene            complement(<378219..>379199)
                     /gene="SPS100"
                     /locus_tag="YHR139C"
                     /db_xref="GeneID:856541"
     mRNA            complement(<378219..>379199)
                     /gene="SPS100"
                     /locus_tag="YHR139C"
                     /product="Sps100p"
                     /transcript_id="NM_001179269.1"
                     /db_xref="GI:296145516"
                     /db_xref="GeneID:856541"
     CDS             complement(378219..379199)
                     /gene="SPS100"
                     /locus_tag="YHR139C"
                     /note="Protein required for spore wall maturation;
                     expressed during sporulation; may be a component of the
                     spore wall; expression also induced in cells treated with
                     the mycotoxin patulin; SPS100 has a paralog, YGP1, that
                     arose from the whole genome duplication"
                     /codon_start=1
                     /product="Sps100p"
                     /protein_id="NP_012007.1"
                     /db_xref="GI:6321931"
                     /db_xref="SGD:S000001181"
                     /db_xref="GeneID:856541"
                     /translation="MKFTSVLAFFLATLTASATPLYKRQNVTSGGGTVPVIITGGPAV
                     SGSQSNVTTTTLFNSTSTLNITQLYQIATQVNQTLQSESSSGIIIVTNWRSIETLSFF
                     CSIVFNTSKTIVITENFLWGVPILSSSDAEGRGTLVAGRDKVVYSGVFPPYTVPVGVL
                     SGQKNVQWFFDACEPTLIASNSTIRTQYSNFTSAQISSNASSGTNTSSSSSSPLVPII
                     YEEGYSQSLIQSLSSSIQGLVVVSSGTSHNSTVASWTSVDFPVVYASDGSSGHDGSGI
                     GFISNTSIPQGAISAGYLSPIQAQTLLSIAIHNQVTSSSELQQIFPVSQQ"
     gene            <380572..>381291
                     /locus_tag="YHR140W"
                     /db_xref="GeneID:856543"
     mRNA            <380572..>381291
                     /locus_tag="YHR140W"
                     /product="hypothetical protein"
                     /transcript_id="NM_001179270.1"
                     /db_xref="GI:296145517"
                     /db_xref="GeneID:856543"
     CDS             380572..381291
                     /locus_tag="YHR140W"
                     /note="Putative integral membrane hypothetical protein"
                     /codon_start=1
                     /product="hypothetical protein"
                     /protein_id="NP_012009.1"
                     /db_xref="GI:6321933"
                     /db_xref="SGD:S000001182"
                     /db_xref="GeneID:856543"
                     /translation="MMSCLVPTRFTLTLNTACLLTSTWGFVRATSVVLPPSLSKAGHK
                     QFLTIISIIATIINNAVNISNYYIQRNNKMNLETKKKSDFISRHVTLPVSLVLESIVA
                     TVYWPLRLFFVNLIMHGVESTAKTPFPMTVDMAIHLYPILYLLADHYLSGSGTKFKLS
                     NKHAWLIVTSLAFSYFQYLAFLIDAGQGQAYPYPFLDVNEPYKSIIFVVVATITWAYY
                     VFYQKFPPKYIKKSAKKGDKN"
     gene            381540..381727
                     /locus_tag="snR32"
                     /db_xref="GeneID:9164901"
     ncRNA           381540..381727
                     /ncRNA_class="snoRNA"
                     /locus_tag="snR32"
                     /product="SNR32"
                     /note="H/ACA box small nucleolar RNA (snoRNA); guides
                     pseudouridylation of large subunit (LSU) rRNA at position
                     U2191"
                     /transcript_id="NR_132188.1"
                     /db_xref="GI:831416113"
                     /db_xref="SGD:S000007297"
                     /db_xref="GeneID:9164901"
     gene            complement(<381990..>382751)
                     /gene="RPL42B"
                     /locus_tag="YHR141C"
                     /gene_synonym="MAK18"
                     /db_xref="GeneID:856544"
     mRNA            complement(join(<381990..382306,382748..>382751))
                     /gene="RPL42B"
                     /locus_tag="YHR141C"
                     /gene_synonym="MAK18"
                     /product="ribosomal 60S subunit protein L42B"
                     /transcript_id="NM_001179271.1"
                     /db_xref="GI:296145518"
                     /db_xref="GeneID:856544"
     CDS             complement(join(381990..382306,382748..382751))
                     /gene="RPL42B"
                     /locus_tag="YHR141C"
                     /gene_synonym="MAK18"
                     /note="Ribosomal 60S subunit protein L42B; required for
                     propagation of the killer toxin-encoding M1
                     double-stranded RNA satellite of the L-A double-stranded
                     RNA virus; homologous to mammalian ribosomal protein L36A,
                     no bacterial homolog; RPL42B has a paralog, RPL42A, that
                     arose from the whole genome duplication"
                     /codon_start=1
                     /product="ribosomal 60S subunit protein L42B"
                     /protein_id="NP_012010.1"
                     /db_xref="GI:6321934"
                     /db_xref="SGD:S000001183"
                     /db_xref="GeneID:856544"
                     /translation="MVNVPKTRKTYCKGKTCRKHTQHKVTQYKAGKASLFAQGKRRYD
                     RKQSGFGGQTKPVFHKKAKTTKKVVLRLECVKCKTRAQLTLKRCKHFELGGEKKQKGQ
                     ALQF"
     gene            <383538..>384488
                     /gene="CHS7"
                     /locus_tag="YHR142W"
                     /db_xref="GeneID:856545"
     mRNA            <383538..>384488
                     /gene="CHS7"
                     /locus_tag="YHR142W"
                     /product="Chs7p"
                     /transcript_id="NM_001179272.1"
                     /db_xref="GI:296145519"
                     /db_xref="GeneID:856545"
     CDS             383538..384488
                     /gene="CHS7"
                     /locus_tag="YHR142W"
                     /note="hypothetical protein; may be involved in chitin
                     biosynthesis by regulation of Chs3p export from the ER;
                     relocalizes from bud neck to ER upon DNA replication
                     stress"
                     /codon_start=1
                     /product="Chs7p"
                     /protein_id="NP_012011.1"
                     /db_xref="GI:6321935"
                     /db_xref="SGD:S000001184"
                     /db_xref="GeneID:856545"
                     /translation="MAFSDFAAICSKTPLPLCSVIKSKTHLILSNSTIIHDFDPLNLN
                     VGVLPRCYARSIDLANTVIFDVGNAFINIGALGVILIILYNIRQKYTAIGRSEYLYFF
                     QLTLLLIIFTLVVDCGVSPPGSGSYPYFVAIQIGLAGACCWALLIIGFLGFNLWEDGT
                     TKSMLLVRGTSMLGFIANFLASILTFKAWITDHKVATMNASGMIVVVYIINAIFLFVF
                     VICQLLVSLLVVRNLWVTGAIFLGLFFFVAGQVLVYAFSTQICEGFKHYLDGLFFGSI
                     CNVFTLMMVYKTWDMTTDDDLEFGVSVSKDGDVVYDNGFM"
     gene            <385510..>386487
                     /gene="DSE2"
                     /locus_tag="YHR143W"
                     /db_xref="GeneID:856546"
     mRNA            <385510..>386487
                     /gene="DSE2"
                     /locus_tag="YHR143W"
                     /product="Dse2p"
                     /transcript_id="NM_001179274.1"
                     /db_xref="GI:296145520"
                     /db_xref="GeneID:856546"
     CDS             385510..386487
                     /gene="DSE2"
                     /locus_tag="YHR143W"
                     /note="Daughter cell-specific secreted protein with
                     similarity to glucanases; degrades cell wall from the
                     daughter side causing daughter to separate from mother;
                     expression is repressed by cAMP"
                     /codon_start=1
                     /product="Dse2p"
                     /protein_id="NP_012012.1"
                     /db_xref="GI:6321936"
                     /db_xref="SGD:S000001186"
                     /db_xref="GeneID:856546"
                     /translation="MKFNFSTIFNILFFLFTLIEANSNGETVKLITSDGIVYSYAVYT
                     KTLAPARVVVKTISYTTTRVYPITLANSVVSSTTEKITEVSTVSASEQVSATQTNSLV
                     STSTVSTISPTISSGSSTSSSSTYDIESSQSIESSGTSSATAEPSASSGFRLTSSSAF
                     VSSTAPFSSQLSSSSSSETSSSSFSTSSSSAPLSLTSSSSSSSSFATIITLAPSSSKS
                     GNSQLTLASSSSTSAVESSQTGSTIARTTSTLVPSSSVDTTSRATTSMPLESSSTQSI
                     SVSSSDGTCYVFYDDDDYYSTVYLTNPSQSVDAATTITSTNTIYATVTI"
     gene            <387233..>387445
                     /gene="RPC10"
                     /locus_tag="YHR143W-A"
                     /gene_synonym="RPB12"
                     /db_xref="GeneID:856547"
     mRNA            <387233..>387445
                     /gene="RPC10"
                     /locus_tag="YHR143W-A"
                     /gene_synonym="RPB12"
                     /product="DNA-directed RNA polymerase core subunit RPB12"
                     /transcript_id="NM_001179273.1"
                     /db_xref="GI:296145521"
                     /db_xref="GeneID:856547"
     CDS             387233..387445
                     /gene="RPC10"
                     /locus_tag="YHR143W-A"
                     /gene_synonym="RPB12"
                     /note="RNA polymerase subunit ABC10-alpha, found in RNA
                     pol I, II, and III; relocalizes from nucleolus to
                     cytoplasm upon DNA replication stress"
                     /codon_start=1
                     /product="DNA-directed RNA polymerase core subunit RPB12"
                     /protein_id="NP_012013.1"
                     /db_xref="GI:6321937"
                     /db_xref="SGD:S000001185"
                     /db_xref="GeneID:856547"
                     /translation="MSREGFQIPTNLDAAAAGTSQARTATLKYICAECSSKLSLSRTD
                     AVRCKDCGHRILLKARTKRLVQFEAR"
     gene            complement(<387788..>388726)
                     /gene="DCD1"
                     /locus_tag="YHR144C"
                     /db_xref="GeneID:856548"
     mRNA            complement(<387788..>388726)
                     /gene="DCD1"
                     /locus_tag="YHR144C"
                     /product="Dcd1p"
                     /transcript_id="NM_001179275.1"
                     /db_xref="GI:296145522"
                     /db_xref="GeneID:856548"
     CDS             complement(387788..388726)
                     /gene="DCD1"
                     /locus_tag="YHR144C"
                     /EC_number="3.5.4.12"
                     /note="Deoxycytidine monophosphate (dCMP) deaminase;
                     involved in dUMP and dTMP biosynthesis; expression is NOT
                     cell cycle regulated"
                     /codon_start=1
                     /product="Dcd1p"
                     /protein_id="NP_012014.1"
                     /db_xref="GI:6321938"
                     /db_xref="SGD:S000001187"
                     /db_xref="GeneID:856548"
                     /translation="MLIGVSGTKFCGCEDVINMLVDHFHFELLNHLDNPEEILDYATK
                     NYTKNSVIFLEKLSLLEKLEKRPFFVHLSIDAPVTTRVALYRKTTQAESLSLEQIIQA
                     IDQHDFQPEGIKLREKSHLRFKIVNEDRRGRRQSLINNITTQLKILDDKEKQMAPLMR
                     PSWDSYFMKLATLAASRSNCMKRRVGCVIVRECRVIATGYNGTPRHLTNCFNGGCPRC
                     NDGDSRNLHTCLCLHAEENALLEAGRDRVGQNATLYCDTCPCLTCSVKIVQTGISEVV
                     YSQSYRMDEESFKVLKNAGITVRQFSFTEEPRIVMI"
     gene            complement(388893..388995)
                     /gene="SUF8"
                     /locus_tag="tP(UGG)H"
                     /db_xref="GeneID:856549"
     tRNA            complement(join(388893..388928,388960..388995))
                     /gene="SUF8"
                     /locus_tag="tP(UGG)H"
                     /product="tRNA-Pro"
                     /note="Proline tRNA (tRNA-Pro), predicted by tRNAscan-SE
                     analysis; target of K. lactis zymocin; can mutate to
                     suppress +1 frameshift mutations in proline codons;
                     tP(UGG)H"
                     /db_xref="SGD:S000006682"
                     /db_xref="GeneID:856549"
     LTR             complement(389177..389509)
                     /note="Ty2 LTR"
                     /db_xref="SGD:S000006997"
     LTR             complement(389613..389845)
                     /note="Ty1 LTR"
                     /db_xref="SGD:S000006998"
     gene            <390300..>391697
                     /gene="CRP1"
                     /locus_tag="YHR146W"
                     /db_xref="GeneID:856551"
     mRNA            <390300..>391697
                     /gene="CRP1"
                     /locus_tag="YHR146W"
                     /product="Crp1p"
                     /transcript_id="NM_001179277.1"
                     /db_xref="GI:296145523"
                     /db_xref="GeneID:856551"
     CDS             390300..391697
                     /gene="CRP1"
                     /locus_tag="YHR146W"
                     /note="Protein that binds to cruciform DNA structures;
                     CRP1 has a paralog, MDG1, that arose from the whole genome
                     duplication"
                     /codon_start=1
                     /product="Crp1p"
                     /protein_id="NP_012016.1"
                     /db_xref="GI:6321940"
                     /db_xref="SGD:S000001189"
                     /db_xref="GeneID:856551"
                     /translation="MSSELMFNYTFSWPAGPKDVILTGTFDDWRGTLPLVKTAKGNFE
                     ITMPVKLANKDDTFQFKFIVDGVWCVSDSYKKEHVSEGIENNFLQITDLVETQEVAGA
                     SRIPEAGGLLCGKPPRSAGPPSTSNRKKNKRNNKKRRSKLKKKSTKNNKKSNESLDDN
                     EEEDGVTGTTTEDVTGTSREETPLAEPTNVSKEAPGNFHILPIDQSADTTQSNGIIGG
                     PGPVLVPNPGEIKEFTEIRDVDARELNERLNKKEEVPEPVAGPIVESSVTEKSPALPQ
                     ADDPIVETKEVAHNVQELTPQVEAVTPLINEPEPLPTPEAQISIPESSKVEPVEGSLQ
                     SKLVEKRESTEGVLDGSKKVENKAKKDEEVFTLDPIVNKAPKLPLTDEQTAEGRKSPA
                     VSEEKEKKKKQEKGSKEVKRSETSKEKKPSAKEVKKQTVKAPKKQTASPLSSSTEEPK
                     KKKTGFFGKLKKLFK"
     rep_origin      392180..392395
                     /note="ARS818;
                     Autonomously Replicating Sequence"
                     /db_xref="SGD:S000118360"
     gene            complement(<392639..>393283)
                     /gene="MRPL6"
                     /locus_tag="YHR147C"
                     /db_xref="GeneID:856552"
     mRNA            complement(<392639..>393283)
                     /gene="MRPL6"
                     /locus_tag="YHR147C"
                     /product="mitochondrial 54S ribosomal protein YmL16"
                     /transcript_id="NM_001179278.1"
                     /db_xref="GI:296145524"
                     /db_xref="GeneID:856552"
     CDS             complement(392639..393283)
                     /gene="MRPL6"
                     /locus_tag="YHR147C"
                     /note="Mitochondrial ribosomal protein of the large
                     subunit"
                     /codon_start=1
                     /product="mitochondrial 54S ribosomal protein YmL16"
                     /protein_id="NP_012017.1"
                     /db_xref="GI:6321941"
                     /db_xref="SGD:S000001190"
                     /db_xref="GeneID:856552"
                     /translation="MSFIQRRLLSQTLFLRSQVGSLPLYISPEVQVSINALSMPRIIR
                     KGRTSMNISQNITVKGPKGELSVEVPDFLHLDKDEKHGKINVTVQNSEDKHQRSMWGT
                     VRSLINNHIIGVTEGHLAVLRFVGTGYRAQLENDGKFVNVKVGASIKQGLDVPEGIVV
                     KTPAPTSLIIEGCNKQQVLLFAAKLRKFHPPEPYKGKGIYVNDETIKLKDKKIK"
     gene            <393534..>394085
                     /gene="IMP3"
                     /locus_tag="YHR148W"
                     /db_xref="GeneID:856553"
     mRNA            <393534..>394085
                     /gene="IMP3"
                     /locus_tag="YHR148W"
                     /product="Imp3p"
                     /transcript_id="NM_001179279.1"
                     /db_xref="GI:296145525"
                     /db_xref="GeneID:856553"
     CDS             393534..394085
                     /gene="IMP3"
                     /locus_tag="YHR148W"
                     /note="Component of the SSU processome; SSU processome is
                     required for pre-18S rRNA processing, essential protein
                     that interacts with Mpp10p and mediates interactions of
                     Imp4p and Mpp10p with U3 snoRNA"
                     /codon_start=1
                     /product="Imp3p"
                     /protein_id="NP_012018.1"
                     /db_xref="GI:6321942"
                     /db_xref="SGD:S000001191"
                     /db_xref="GeneID:856553"
                     /translation="MVRKLKHHEQKLLKKVDFLEWKQDQGHRDTQVMRTYHIQNREDY
                     HKYNRICGDIRRLANKLSLLPPTDPFRRKHEQLLLDKLYAMGVLTTKSKISDLENKVT
                     VSAICRRRLPVIMHRLKMAETIQDAVKFIEQGHVRVGPNLINDPAYLVTRNMEDYVTW
                     VDNSKIKKTLLRYRNQIDDFDFS"
     gene            complement(<394455..>396659)
                     /gene="SKG6"
                     /locus_tag="YHR149C"
                     /db_xref="GeneID:856554"
     mRNA            complement(<394455..>396659)
                     /gene="SKG6"
                     /locus_tag="YHR149C"
                     /product="Skg6p"
                     /transcript_id="NM_001179280.1"
                     /db_xref="GI:296145526"
                     /db_xref="GeneID:856554"
     CDS             complement(394455..396659)
                     /gene="SKG6"
                     /locus_tag="YHR149C"
                     /note="Integral membrane protein; localizes primarily to
                     growing sites such as the bud tip or the cell periphery;
                     potential Cdc28p substrate; Skg6p interacts with Zds1p and
                     Zds2p; SKG6 has a paralog, TOS2, that arose from the whole
                     genome duplication"
                     /codon_start=1
                     /product="Skg6p"
                     /protein_id="NP_012019.1"
                     /db_xref="GI:6321943"
                     /db_xref="SGD:S000001192"
                     /db_xref="GeneID:856554"
                     /translation="MYHTHMHESLISVTSTVSVSDASYAYARLTRRDDSDSSSSSASS
                     TKNSKSAECTGSKQQCQLPTDSSHSTSVTVGVAVAVPVGVIIIVLAVILCIVYRRSKK
                     EAEEDNDPDFEGDSEFLPTMKDYSPGINHLYSSDSQQDFMEKTLQQPPSDPFVGSMHS
                     SKYNVRSATPPAIGRSWYVDPFQLPQESNDSNSLRDFAMRVQEDGLGGYKVAAESRNA
                     SQTSLHPDNFSNCTPIRASSRFQESESFRSHGSPIHNNQLSRGSATEGANKQFTFPNE
                     DNDSSSVSEEAEVLNESNESASNDAFEFELDNSSEKTHERNLRFGKDDDNYELQDIRE
                     AEHMNDRSSSKSQDDDYYVSLLSPNEEEDIKRMKSIYQVYLDRAKTMKKEEDKADNAN
                     DISQEENRVDNIVQNPLPSIKINNNDNIDNNEVPEAKHLVKEALPLNNTNLAEYGPEM
                     AQSQKQYPVQDTLTVNDTEAAPSNRIASSIYSEAIQPLNYQDQYQQQEQSPVYNGHTQ
                     YPGNGYSGNPQQQGYTAQFVQNPQWYGVPTPQQQQHNHPQTLETIGELPTPAYLAQSA
                     SSHSLTSFKRPNKQQLLQLQTARLNGTALNPVDHPEMFYSPTNDAYYAPQQQGQYMKF
                     NENGAVPSPYQLRQSVVMTNPSDLTAKPSYKPAGSFRSVSATNSRNNSLTTQNNIYLQ
                     QQQQQLYNSRVSGILEETDVVQPPSVGGILPHSGSQDDLRKQLGSSHNYTVN"
     gene            <397251..>398990
                     /gene="PEX28"
                     /locus_tag="YHR150W"
                     /db_xref="GeneID:856555"
     mRNA            <397251..>398990
                     /gene="PEX28"
                     /locus_tag="YHR150W"
                     /product="Pex28p"
                     /transcript_id="NM_001179281.1"
                     /db_xref="GI:296145527"
                     /db_xref="GeneID:856555"
     CDS             397251..398990
                     /gene="PEX28"
                     /locus_tag="YHR150W"
                     /note="Peroxisomal integral membrane peroxin; involved in
                     the regulation of peroxisomal size, number and
                     distribution; genetic interactions suggest that Pex28p and
                     Pex29p act at steps upstream of those mediated by Pex30p,
                     Pex31p, and Pex32p"
                     /codon_start=1
                     /product="Pex28p"
                     /protein_id="NP_012020.1"
                     /db_xref="GI:6321944"
                     /db_xref="SGD:S000001193"
                     /db_xref="GeneID:856555"
                     /translation="MSETSSSRRSASKDAVKSYFAGKYNKVLDSILEAEAAISKSPTV
                     AEDLSGSSSSGNSEMSHPSLTASSATSQGISKKELLQQIAGSLFSTSIERLKTAHSSE
                     VSSTPEYSVNDSYGEQECRECDGVFKCSAHFEGAPEYYDDETESGPALEPMTSNSEKD
                     PFIDVFLDKLISRLVPEKLPEREHFSSKTTIEHDLDTGRVPVFSATTLGSNFKKLSKK
                     MGSIFELQDSIVRLLTWRNPTGTVTSLILFTLICFNPMYLVILPIFRFVYGIVVPGYV
                     RKHPLQRSIYPLKRNHGSSLLYDVCYEGKNEYSYGQQFFSKSFMDTLESRNQEIDEIS
                     ELDKRTENTGELKQGMKVLINLRDMQNMTSGTLHVIEAINSFLRKSSSFQNEECSTKR
                     FFTGFLLIVFLKILSPFVNWSYVCSIFAWCLLIYMHPRAHPKIISFFKTGTMGKEYKN
                     LKKREHQALNMIFDEQPETKFIEIFEIYKKALLPNDWKFFRYSNRIFDPQDPYRRAQQ
                     FPPGVDSLADVIPPTGWSFDPNFEWKIDNDVDRWVVERGLNLPITGEFLFDPMFKRRR
                     LIHRVIKNATPVA"
     gene            complement(<399268..>400848)
                     /gene="MTC6"
                     /locus_tag="YHR151C"
                     /db_xref="GeneID:856556"
     mRNA            complement(<399268..>400848)
                     /gene="MTC6"
                     /locus_tag="YHR151C"
                     /product="Mtc6p"
                     /transcript_id="NM_001179282.1"
                     /db_xref="GI:296145528"
                     /db_xref="GeneID:856556"
     CDS             complement(399268..400848)
                     /gene="MTC6"
                     /locus_tag="YHR151C"
                     /note="hypothetical protein; mtc6 is synthetically sick
                     with cdc13-1"
                     /codon_start=1
                     /product="Mtc6p"
                     /protein_id="NP_012021.1"
                     /db_xref="GI:6321945"
                     /db_xref="SGD:S000001194"
                     /db_xref="GeneID:856556"
                     /translation="MWILIYLFIIWSSLRTWVTAVDSTTTVGDDLNETVSASVWPTMS
                     PQMTVAFRSQRDVMGNLTIDQLPYVGLNLRRVLLNNETSMVNEGNNTRLLTLFKSMLS
                     SEANAFVLDLEQYNNDLRVVDTTLLFSDVLTALQSFIFSTQNNLYANIIVLLLNISAP
                     ELDSTEYRHQNQTLNTTYILDKNLGNSFIYKPTDLQSDRAKNNTWNIYGKSSIDGWPT
                     LGSVLYEQKKRLVIGELTDFFNETTAPYIFPHDVFHYEQGNSTLDCPSTVEGLTDLSS
                     IHWRFLDSLFNSVDIKEYISCGLSPIISNSAYVNNVTQLADIIHEGSVWSWDSDQPSV
                     TQSTSKSGSSSGTLEAYNCVLLYYFANNETVTWRVGNCYNSNIGLCRYENMAFRWLVR
                     SNKATYFDFDSYQGSKCPDQYSFNIPRSPLEQRSFIAYMRNSSFSDTQIWIDLNSISV
                     SNCWVSGGPYASCPYEKVISRRNFVTMMVPASVCSFALLCIVVYLSVLRVPIYDNRKN
                     WRRVINKISKSELEGVPS"
     gene            <401434..>401955
                     /gene="SPO12"
                     /locus_tag="YHR152W"
                     /gene_synonym="SDB21"
                     /db_xref="GeneID:856557"
     mRNA            <401434..>401955
                     /gene="SPO12"
                     /locus_tag="YHR152W"
                     /gene_synonym="SDB21"
                     /product="Spo12p"
                     /transcript_id="NM_001179283.1"
                     /db_xref="GI:296145529"
                     /db_xref="GeneID:856557"
     CDS             401434..401955
                     /gene="SPO12"
                     /locus_tag="YHR152W"
                     /gene_synonym="SDB21"
                     /note="Nucleolar hypothetical protein; positive regulator
                     of mitotic exit; involved in regulating release of Cdc14p
                     from the nucleolus in early anaphase, may play similar
                     role in meiosis; SPO12 has a paralog, BNS1, that arose
                     from the whole genome duplication"
                     /codon_start=1
                     /product="Spo12p"
                     /protein_id="NP_012022.1"
                     /db_xref="GI:6321946"
                     /db_xref="SGD:S000001195"
                     /db_xref="GeneID:856557"
                     /translation="MSNKASDQSARTASILKTDITRENTITRSSSSNNDNYHHHNNIN
                     NYNESAKTGEDANKENIPNLEEEIAAFRIFRKKSTSNLKSSHTTSNLVKKTMFKRDLL
                     KQDPKRKLQLQQRFASPTDRLVSPCSLKLNEHKVKMFGKKKKVNPMKLNFKGNLAADS
                     EDVEIDEDEEYFY"
     gene            complement(<402086..>402682)
                     /gene="SPO16"
                     /locus_tag="YHR153C"
                     /db_xref="GeneID:856558"
     mRNA            complement(<402086..>402682)
                     /gene="SPO16"
                     /locus_tag="YHR153C"
                     /product="Spo16p"
                     /transcript_id="NM_001179284.1"
                     /db_xref="GI:296145530"
                     /db_xref="GeneID:856558"
     CDS             complement(402086..402682)
                     /gene="SPO16"
                     /locus_tag="YHR153C"
                     /note="Meiosis-specific protein involved in synaptonemal
                     complex assembly; implicated in regulation of crossover
                     formation; required for sporulation"
                     /codon_start=1
                     /product="Spo16p"
                     /protein_id="NP_012023.1"
                     /db_xref="GI:6321947"
                     /db_xref="SGD:S000001196"
                     /db_xref="GeneID:856558"
                     /translation="MSEFFWDVQKIQEISNVEEHSVVKCVTVNTSRLISQLNEELQDE
                     ESGVNFIVTQLQLLINNVYEKIQKSPGVPAHRSLMINLNFTRLKFSIAYWDILLERSL
                     DLINGPSKTGARYFITEVTPVDRSRYVENNQYFLAFKANQRLTRNSVDMDEFIDFEIL
                     IKQIIFDLFKKNGIPDQDFEAILSRFHNLESLVVAFNE"
     gene            <402966..>406178
                     /gene="RTT107"
                     /locus_tag="YHR154W"
                     /gene_synonym="ESC4"
                     /db_xref="GeneID:856559"
     mRNA            <402966..>406178
                     /gene="RTT107"
                     /locus_tag="YHR154W"
                     /gene_synonym="ESC4"
                     /product="Rtt107p"
                     /transcript_id="NM_001179285.1"
                     /db_xref="GI:296145531"
                     /db_xref="GeneID:856559"
     CDS             402966..406178
                     /gene="RTT107"
                     /locus_tag="YHR154W"
                     /gene_synonym="ESC4"
                     /note="Protein implicated in Mms22-dependent DNA repair
                     during S phase; involved in recruiting the SMC5/6 complex
                     to double-strand breaks; DNA damage induces
                     phosphorylation by Mec1p at one or more SQ/TQ motifs;
                     interacts with Mms22p and Slx4p; has four BRCT domains;
                     has a role in regulation of Ty1 transposition; relative
                     distribution to nuclear foci increases upon DNA
                     replication stress"
                     /codon_start=1
                     /product="Rtt107p"
                     /protein_id="NP_012024.1"
                     /db_xref="GI:6321948"
                     /db_xref="SGD:S000001197"
                     /db_xref="GeneID:856559"
                     /translation="MSTSLLFEQLNFLILVAAEAELPIAHSTRKLLMDNSCNNCQIYE
                     LYNENLKDVKTDKDWFMNKFGPQTVHFVISNTINFPFYKIVYFDLLIPVVSHTWVQDS
                     VKTKRHLRTNMYSPNPFHLLRDCQVYISKSSFNKCEYILYSDLLHLLGGTLVNYISNR
                     TTHVIVQSPQDPIIATVSKLTFGSFSSSSTNKHTEKPLREWKFVYPIWILYHFKMAKP
                     LKGELATLCELDMQDTSEEQLFAKWEEVIGDKQTSSSQLTLHPNKTLFKNHHFAISPD
                     LNFFTPLYWFLKGFIEDLDGKVTPLSFSDDLKSVYQAFPDIDCYIGHSANSPILEKTK
                     SIKPEIHVGNVSWLFYMFALQKFTPVSQCKLIHQPFHAKLFTSKELTVAYTNYFGSQR
                     FYIQRLVEILGGLSTPELTRKNTHLITKSTIGKKFKVAKKWSLDPQNAIIVTNHMWLE
                     QCYMNNSKLNPKDSRFQNFKLDDNMGWNIGQIGMDHSSLPTPKNLSMVTYDTQSISEK
                     PPPTNDQMDQINDNTNVLSKKDGTPISSFENSIDEKIDKLQKISGEVAVTHSGDLERS
                     FVSRPSRASFPVVDSKKSNLQKKDSNSDISMETEVFCEGHEKREEKEFTKPITEYDAP
                     KKQEIREQSRKKNDIDYKKEEEETELQVQLGQRTKREIKTSKKNEKEKETNECHIEVD
                     QMTNEKQGEESTGKLISTEDVTSKKDTDKFSHLFEGLSDNDDHINDEKPAVNSKYTTP
                     KTSQNITSGVDTPTTAQTQVFMPSSGNSRLAKTQAAKRLHTDIESLNEFQKNFKRKRI
                     DSEEISLSQDVERSNNNKELATKAEKILARFNELPNYDLKAVCTGCFHDGFNEVDIEI
                     LNQLGIKIFDNIKETDKLNCIFAPKILRTEKFLKSLSFEPLKFALKPEFIIDLLKQIH
                     SKKDKLSQININLFDYEINGINESIISKTKLPTKVFERANIRCINLVNDIPGGVDTIG
                     SVLKAHGIEKINVLRSKKCTFEDIIPNDVSKQENGGIFKYVLIVTKASQVKKFTKLIN
                     DRDKNETILIVEWNWCVESIFHLNVDFTSKKNVLYQKKNN"
     gene            <407103..>410789
                     /gene="YSP1"
                     /locus_tag="YHR155W"
                     /db_xref="GeneID:856560"
     mRNA            <407103..>410789
                     /gene="YSP1"
                     /locus_tag="YHR155W"
                     /product="Ysp1p"
                     /transcript_id="NM_001179286.1"
                     /db_xref="GI:296145532"
                     /db_xref="GeneID:856560"
     CDS             407103..410789
                     /gene="YSP1"
                     /locus_tag="YHR155W"
                     /note="Mitochondrial protein; potential role in promoting
                     mitochondrial fragmentation during programmed cell death
                     in response to high levels of alpha-factor mating
                     pheromone or the drug amiodarone; YSP1 has a paralog,
                     SIP3, that arose from the whole genome duplication"
                     /codon_start=1
                     /product="Ysp1p"
                     /protein_id="NP_012025.1"
                     /db_xref="GI:6321949"
                     /db_xref="SGD:S000001198"
                     /db_xref="GeneID:856560"
                     /translation="MHEHKAELRLITVALNEASTDSPSFRASVNYFHTRMESLSSWMH
                     STVDYVENTYKPSFQDFQRIKETLFSQLLPSPILLSNGFVSNQPYTPLLVRDFTRDVS
                     DLSNTVMKIILGDENSQYTAALSALSSDAINPYFNKRKTFEYYQRKYDSFLTDFLAAT
                     NDGNTLIPQNLQNETFKLVDIKHKYIEASLDLTEAISLMKVNLDKFLIETIDIVRKNN
                     VITTKDTKDVIDITPELTETLKDWTDWIESNLQTLQALSSKLSEAKYAILKLSLARMK
                     PSRLIQDYDLKSIQNLKFNLPKSISNGNNSEEKGLSGWLYMKTTVGHDPKRVVWVRRW
                     CFLQNNVFGVFSLSPSKTYVEETDKFGILWITVEYLPKEPRNFCFKLRIQNPNCKTEE
                     ENTYIDIILQAESIDELKSWINTLTSHKRIALSIKEENDPRYQLARKKIEPQFFEFAS
                     SSSTSTDKLLTSFSSKTLTLVEELKKNYMSEDDIYSIIDNKAYHLRVISTPIATQLTH
                     LALFSTFLSVSNYYPCATQANTWGTANWNDLSYLVNPLKGSSVHKPATVSNSSRFSVS
                     YPDYYPYSLKVDDIQFRSIFFSVNHDFLQVPKELVLLRYSSVWCPNNKQKFASMAFVT
                     LNHIYVYLNISGFSYLRRIDLLDIDSIEYDKSPKHVSSRMLHMQRGDGLRFNMSVFFT
                     DRRAVASKLQFLIENKAMHIPKGEKEVLEIFQELDEEIENEKKIIKDNLSESEHYSKD
                     YDYLLKSTYDHHFENTNETPMELMSRKLRLEREAWCYFQDNFKVGSKTLFHVLFGDKS
                     QVFPSSLFLCKKGSNLNNNSYWERIRRAKEDASCQFELCRKLQFQLNRTSNFIKDLLW
                     LKDDNDNFKLVLQQRVTKIKQGYYFEVEEGPIIVKFPLCHPLLLRVRFIIAECITSQG
                     ESLKKCDLAILYDFNYVESIDKLNTKVEKLWLFERIHLNWALRYCKLEHSEINRKTRE
                     YLKKFNDREKMSDVIKLCGFLGVLPKERIENDEKAGDFMQPVYINYDFLSLSKIFTKL
                     TVFYLSSVIIKTMKVLLAMVMVIFKCFSKVNKTLYYCLLISAVTNLFFVGKSIHSYFS
                     VKSAETLFQNYANGDQRGLQIMHRSLTVPDLNLLTRKMMDNDQENPVFKRFDEDKNAY
                     QYKGTRQEIAIKRNQVLTELKILQNTEKELVQGSYRKFIITERDKCITTQNEIFDLWI
                     NDTKLQDYCMACFAEYNRLSAIPV"
     gene            411228..411317
                     /locus_tag="snR71"
                     /db_xref="GeneID:9164902"
     ncRNA           411228..411317
                     /ncRNA_class="snoRNA"
                     /locus_tag="snR71"
                     /product="SNR71"
                     /note="C/D box small nucleolar RNA (snoRNA); guides
                     2'-O-methylation of large subunit (LSU) rRNA at position
                     A2946"
                     /transcript_id="NR_132189.1"
                     /db_xref="GI:831416114"
                     /db_xref="SGD:S000006462"
                     /db_xref="GeneID:9164902"
     gene            complement(<411384..>412406)
                     /gene="LIN1"
                     /locus_tag="YHR156C"
                     /gene_synonym="SNU40"
                     /db_xref="GeneID:856561"
     mRNA            complement(<411384..>412406)
                     /gene="LIN1"
                     /locus_tag="YHR156C"
                     /gene_synonym="SNU40"
                     /product="Lin1p"
                     /transcript_id="NM_001179287.1"
                     /db_xref="GI:296145533"
                     /db_xref="GeneID:856561"
     CDS             complement(411384..412406)
                     /gene="LIN1"
                     /locus_tag="YHR156C"
                     /gene_synonym="SNU40"
                     /note="Non-essential component of U5 snRNP; nuclear
                     protein; physically interacts with Irr1p of cohesin
                     complex; may link together proteins involved in chromosome
                     segregation, mRNA splicing and DNA replication"
                     /codon_start=1
                     /product="Lin1p"
                     /protein_id="NP_012026.1"
                     /db_xref="GI:6321950"
                     /db_xref="SGD:S000001199"
                     /db_xref="GeneID:856561"
                     /translation="MKYTQYPNSSKLKRNSDRREHDEKLSDELHNQSTIYEDEELSRA
                     EYDSDSDSSVEDSTDNENSGKEMDEKSYEKNEDHVEDHRKRKKSKIQLLDIAEFKKEN
                     LADLDYQIGNSESKVEKGVNIEPFNIDDEIKHGVFDKDGNYIKTENATENDQQDNEEW
                     MNDVINTEEVNRLEKEQSVKTQNSRHYMVHEALNLLKFFLVDENETVLESLGRLNKLR
                     KIAISKKNKSLKYVIHGIELLSDLINILEKKGFSEVYEYNRLKVQDAIEEEIFDDSSR
                     IVNHKTKLWGFKWLNKLDEYHGLYTNYEMSYWQKSYFKNSVIVKFHSEPDRDENWIHV
                     SCLSFM"
     gene            <412907..>413455
                     /gene="REC104"
                     /locus_tag="YHR157W"
                     /db_xref="GeneID:856562"
     mRNA            <412907..>413455
                     /gene="REC104"
                     /locus_tag="YHR157W"
                     /product="Rec104p"
                     /transcript_id="NM_001179288.1"
                     /db_xref="GI:296145534"
                     /db_xref="GeneID:856562"
     CDS             412907..413455
                     /gene="REC104"
                     /locus_tag="YHR157W"
                     /note="Protein involved in early stages of meiotic
                     recombination; required for meiotic crossing over; forms a
                     complex with Rec102p and Spo11p necessary during the
                     initiation of recombination"
                     /codon_start=1
                     /product="Rec104p"
                     /protein_id="NP_012027.1"
                     /db_xref="GI:6321951"
                     /db_xref="SGD:S000001200"
                     /db_xref="GeneID:856562"
                     /translation="MSIEEEDTNKITCTQDFLHQYFVTERVSIQFGLNNKTVKRINKD
                     EFDKAVNCIMSWTNYPKPGLKRTASTYLLSNSFKKSATVSLPFILGDPVCMPKRVESN
                     NNDTCLLYSDTLYDDPLIQRNDQAGDEIEDEFSFTLLRSEVNEIRPISSSSTAQILQS
                     DYSALMYERQASNGSIFQFSSP"
     gene            complement(<413685..>417179)
                     /gene="KEL1"
                     /locus_tag="YHR158C"
                     /db_xref="GeneID:856563"
     mRNA            complement(<413685..>417179)
                     /gene="KEL1"
                     /locus_tag="YHR158C"
                     /product="Kel1p"
                     /transcript_id="NM_001179289.1"
                     /db_xref="GI:296145535"
                     /db_xref="GeneID:856563"
     CDS             complement(413685..417179)
                     /gene="KEL1"
                     /locus_tag="YHR158C"
                     /note="Protein required for proper cell fusion and cell
                     morphology; functions in a complex with Kel2p to
                     negatively regulate mitotic exit, interacts with Tem1p and
                     Lte1p; localizes to regions of polarized growth; potential
                     Cdc28p substrate; KEL1 has a paralog, KEL2, that arose
                     from the whole genome duplication"
                     /codon_start=1
                     /product="Kel1p"
                     /protein_id="NP_012028.1"
                     /db_xref="GI:6321952"
                     /db_xref="SGD:S000001201"
                     /db_xref="GeneID:856563"
                     /translation="MAGFSFAKKFTHKKHGKTPSDASISDQSREASLSTPPNEKFFTK
                     QETPQKGRQFSQGYHSNVNKTSSPPMFARKQVSESRIQPSAVPPQQRNVSGPSTTLHK
                     QLSKQREYTVWNRIKLQNSPFPRYRHVASAYVTDKNQIYVIGGLHDQSVYGDTWILTA
                     FDNATRFSTTTIDISEATPPPRVGHAAVLCGNAFVVFGGDTHKVNKEGLMDDDIYLLN
                     INSYKWTVPAPVGPRPLGRYGHKISIIATTQMKTKLYVFGGQFDDTYFNDLAVYDLSS
                     FRRPDSHWEFLKPRTFTPPPITNFTMISYDSKLWVFGGDTLQGLVNDVFMYDPAINDW
                     FIIDTTGEKPPPVQEHATVVYNDLMCVVGGKDEHDAYLNSVYFLNLKSRKWFKLPVFT
                     AGIPQGRSGHSLTLLKNDKILIMGGDKFDYARVEEYDLHTSDIDMQRGTIVYTLDLAR
                     IKDLCPGVMDVPTDTPTPRNGNLDLATPVTPTSHQTKNMNVPISAAPLASAPSPAPKD
                     FSDADRLNREVHNRNVSTEHQNQSHPVNSESHLIAEPNILTPYVPSESSQTPVMKITS
                     NKPFDTPTIQKEPDLSETMDPTVGNQRIPSSIYGDNLTPANQIKNNSPILETLPSNEI
                     KTPQNGNIEEIKHLPDADEKIDSTTTFDQEINGDKLGTSSMSKVEEDGNVADEDDEIG
                     VAQMASSPSKDQFKIKHYNESSELSQNNTEIDKLSEPVDITIKKSDTAGHDSANHVID
                     ASDEKNVSPMGDVPTDTKNEEASVPINRDATTEVVDRALFEKLRSELQSLKELTHEKA
                     LEAGAHIKELETELWQLKSQKNSGTTKEIDELDSVRLQSKCEILEADNHSLEDKVNEL
                     EELVNSKFLDIENLNEVIQFQNEKIKSLELEPNYKEKLEELQIEHENLSRENERLKNE
                     SKQHNEDIINNVANYSSQLGSLISHWKENRANSSFLESSSSLISVSDENGEKTVGEPY
                     GDQSRHHRVVINKLTNRLDDLLERSQELTISKEKLSSEYHALKMEHSSLSQDVLVKEN
                     EIKKIQNDYKESISSMDSASKALMVSQRELEKYKSLNKKLIDELDELKFKNGVCSENF
                     ENGLRSTEESSNNVKNSNSIRENQFNIKINDLKAELFITNQERDDLKSEVLELKKRLL
                     NLENNTKQVNEDADSDLL"
     gene            <417549..>419063
                     /gene="TDA11"
                     /locus_tag="YHR159W"
                     /db_xref="GeneID:856564"
     mRNA            <417549..>419063
                     /gene="TDA11"
                     /locus_tag="YHR159W"
                     /product="Tda11p"
                     /transcript_id="NM_001179290.1"
                     /db_xref="GI:296145536"
                     /db_xref="GeneID:856564"
     CDS             417549..419063
                     /gene="TDA11"
                     /locus_tag="YHR159W"
                     /note="hypothetical protein; green fluorescent protein
                     (GFP)-fusion protein localizes to the cytoplasm; potential
                     Cdc28p substrate; null mutant is sensitive to expression
                     of the top1-T722A allele"
                     /codon_start=1
                     /product="Tda11p"
                     /protein_id="NP_012029.1"
                     /db_xref="GI:6321953"
                     /db_xref="SGD:S000001202"
                     /db_xref="GeneID:856564"
                     /translation="MNKFDEFIESNEKDLDVDTSTRNSIISMSPVRKTGRKIRSASSN
                     GYRLEHHRTSSAGSMHSQRLMTPTRLNDQDHPLQAKPDARRVVTRHSSVSVPNAMSKR
                     RSLIQPMVVPTTPESQNNLPSVSHSEGSYGIPLESTTVLSSEQAMASGLRRSRNGSSQ
                     SVNSMIATTIPTNGVDVSALLQSLATKELELLECKQKIEDLKKQTQHEEQNYTRRARE
                     LHELKEQVSKHLDPSLNTPVKNRAFSPVYQNIPLESRTENAGNSSLPSSVSKPKNMGH
                     QSTNQSRSVSPQDIQERRQRDDSSDSSKQSLWSKPLALFNQFDKIIQHEIERTLNWDD
                     SLSGTPEVQEGTPTSNSESSAQQYDNEAPGARQKSPSQGSVSRSLWSFVSDVKAGLLG
                     IEEENDNDVITDNRCDPVYKSDRQHEQKKSTHKITNRGQAEDSGDDSSLNMRKFKTTT
                     KFQKDNAGNNSLTDESGHRTREKKSKRSSNKLSFIGEPDNDNSSVKNSVEMTDF"
     gene            complement(<419221..>420072)
                     /gene="PEX18"
                     /locus_tag="YHR160C"
                     /db_xref="GeneID:856565"
     mRNA            complement(<419221..>420072)
                     /gene="PEX18"
                     /locus_tag="YHR160C"
                     /product="Pex18p"
                     /transcript_id="NM_001179291.1"
                     /db_xref="GI:296145537"
                     /db_xref="GeneID:856565"
     CDS             complement(419221..420072)
                     /gene="PEX18"
                     /locus_tag="YHR160C"
                     /note="Peroxin; required for targeting of peroxisomal
                     matrix proteins containing PTS2; interacts with Pex7p;
                     partially redundant with Pex21p; PEX18 has a paralog,
                     PEX21, that arose from the whole genome duplication"
                     /codon_start=1
                     /product="Pex18p"
                     /protein_id="NP_012030.1"
                     /db_xref="GI:6321954"
                     /db_xref="SGD:S000001203"
                     /db_xref="GeneID:856565"
                     /translation="MNSNRCQTNEVNKFISSTEKGPFTGRDNTLSFNKIGSRLNSPPI
                     LKDKIELKFLQHSEDLNQSRSYVNIRPRTLEDQSYKFEAPNLNDNETSWAKDFRYNFP
                     KNVEPPIENQIANLNINNGLRTSQTDFPLGFYSQKNFNIASFPVVDHQIFKTTGLEHP
                     INSHIDSLINAEFSELEASSLEEDVHTEEENSGTSLEDEETAMKGLASDIIEFCDNNS
                     ANKDVKERLNSSKFMGLMGSISDGSIVLKKDNGTERNLQKHVGFCFQNSGNWAGLEFH
                     DVEDRIA"
     gene            complement(<420373..>422286)
                     /gene="YAP1801"
                     /locus_tag="YHR161C"
                     /db_xref="GeneID:856566"
     mRNA            complement(<420373..>422286)
                     /gene="YAP1801"
                     /locus_tag="YHR161C"
                     /product="Yap1801p"
                     /transcript_id="NM_001179292.1"
                     /db_xref="GI:296145538"
                     /db_xref="GeneID:856566"
     CDS             complement(420373..422286)
                     /gene="YAP1801"
                     /locus_tag="YHR161C"
                     /note="Protein of the AP180 family, involved in clathrin
                     cage assembly; binds Pan1p and clathrin; YAP1801 has a
                     paralog, YAP1802, that arose from the whole genome
                     duplication"
                     /codon_start=1
                     /product="Yap1801p"
                     /protein_id="NP_012031.1"
                     /db_xref="GI:6321955"
                     /db_xref="SGD:S000001204"
                     /db_xref="GeneID:856566"
                     /translation="MTTYFKLVKGATKIKSAPPKQKYLDPILLGTSNEEDFYEIVKGL
                     DSRINDTAWTIVYKSLLVVHLMIREGSKDVALRYYSRNLEFFDIENIRGSNGSASGDM
                     RALDRYDNYLKVRCREFGKIKKDYVRDGYRTLKLNSGNYGSSRNKQHSINIALDHVES
                     LEVQIQALIKNKYTQYDLSNELIIFGFKLLIQDLLALYNALNEGIITLLESFFELSHH
                     NAERTLDLYKTFVDLTEHVVRYLKSGKTAGLKIPVIKHITTKLVRSLEEHLIEDDKTH
                     NTFVPVDSSQGSAGAVVAKSTAQERLEQIREQKRILEAQLKNEQVAISPALTTVTAAQ
                     SYNPFGTDSSMHTNIPMAVANQTQQIANNPFVSQTQPQVMNTPTAHTEPANLNVPEYA
                     AVQHTVNFNPVQDAGVSAQQTGYYSINNHLTPTFTGAGFGGYSVSQDTTAASNQQVSH
                     SQTGSNNPFALHNAATIATGNPAHENVLNNPFSRPNFDEQNTNMPLQQQIISNPFQNQ
                     TYNQQQFQQQKMPLSSINSVMTTPTSMQGSMNIPQRFDKMEFQAHYTQNHLQQQQQQQ
                     QQQQQQQQQQPQQGYYVPATAGANPVTNITGTVQPQNFPFYPQQQPQPEQSQTQQPVL
                     GNQYANNLNLIDM"
     gene            <423072..>423461
                     /gene="MPC2"
                     /locus_tag="YHR162W"
                     /db_xref="GeneID:856567"
     mRNA            <423072..>423461
                     /gene="MPC2"
                     /locus_tag="YHR162W"
                     /product="Mpc2p"
                     /transcript_id="NM_001179293.1"
                     /db_xref="GI:296145539"
                     /db_xref="GeneID:856567"
     CDS             423072..423461
                     /gene="MPC2"
                     /locus_tag="YHR162W"
                     /note="Highly conserved subunit of the mitochondrial
                     pyruvate carrier; a mitochondrial inner membrane complex
                     comprised of Mpc1p and either Mpc2p or Mpc3p mediates
                     mitochondrial pyruvate uptake; more highly expressed in
                     glucose-containing minimal medium than in
                     lactate-containing medium; MPC2 has a paralog, FMP43, that
                     arose from the whole genome duplication"
                     /codon_start=1
                     /product="Mpc2p"
                     /protein_id="NP_012032.1"
                     /db_xref="GI:6321956"
                     /db_xref="SGD:S000001205"
                     /db_xref="GeneID:856567"
                     /translation="MSTSSVRFAFRRFWQSETGPKTVHFWAPTLKWGLVFAGFSDMKR
                     PVEKISGAQNLSLLSTALIWTRWSFVIKPRNILLASVNSFLCLTAGYQLGRIANYRIR
                     NGDSISQLCSYILSGADESKKEITTGR"
     gene            <423724..>424473
                     /gene="SOL3"
                     /locus_tag="YHR163W"
                     /db_xref="GeneID:856568"
     mRNA            <423724..>424473
                     /gene="SOL3"
                     /locus_tag="YHR163W"
                     /product="6-phosphogluconolactonase SOL3"
                     /transcript_id="NM_001179294.1"
                     /db_xref="GI:296145540"
                     /db_xref="GeneID:856568"
     CDS             423724..424473
                     /gene="SOL3"
                     /locus_tag="YHR163W"
                     /EC_number="3.1.1.31"
                     /note="6-phosphogluconolactonase; catalyzes the second
                     step of the pentose phosphate pathway; weak multicopy
                     suppressor of los1-1 mutation; homologous to Sol2p and
                     Sol1p; SOL3 has a paralog, SOL4, that arose from the whole
                     genome duplication"
                     /codon_start=1
                     /product="6-phosphogluconolactonase SOL3"
                     /protein_id="NP_012033.2"
                     /db_xref="GI:82795254"
                     /db_xref="SGD:S000001206"
                     /db_xref="GeneID:856568"
                     /translation="MVTVGVFSERASLTHQLGEFIVKKQDEALQKKSDFKVSVSGGSL
                     IDALYESLVADESLSSRVQWSKWQIYFSDERIVPLTDADSNYGAFKRAVLDKLPSTSQ
                     PNVYPMDESLIGSDAESNNKIAAEYERIVPQVLDLVLLGCGPDGHTCSLFPGETHRYL
                     LNETTKRVAWCHDSPKPPSDRITFTLPVLKDAKALCFVAEGSSKQNIMHEIFDLKNDQ
                     LPTALVNKLFGEKTSWFVNEEAFGKVQTKTF"
     gene            complement(<424610..>429178)
                     /gene="DNA2"
                     /locus_tag="YHR164C"
                     /gene_synonym="WEB2"
                     /db_xref="GeneID:856569"
     mRNA            complement(<424610..>429178)
                     /gene="DNA2"
                     /locus_tag="YHR164C"
                     /gene_synonym="WEB2"
                     /product="bifuctional ATP-dependent DNA helicase/ssDNA
                     endodeoxyribonuclease DNA2"
                     /transcript_id="NM_001179295.1"
                     /db_xref="GI:296145541"
                     /db_xref="GeneID:856569"
     CDS             complement(424610..429178)
                     /gene="DNA2"
                     /locus_tag="YHR164C"
                     /gene_synonym="WEB2"
                     /EC_number="3.6.4.12"
                     /EC_number="3.1.-.-"
                     /note="Tripartite DNA replication factor; has
                     single-stranded DNA-dependent ATPase, ATP-dependent
                     nuclease, and helicase activities; tracking protein for
                     flap cleavage during Okazaki fragment maturation; involved
                     in DNA repair and processing of meiotic DNA double strand
                     breaks; required for normal life span; component of
                     telomeric chromatin, with cell-cycle dependent
                     localization; required for telomerase-dependent telomere
                     synthesis; forms nuclear foci upon DNA replication stress"
                     /codon_start=1
                     /product="bifuctional ATP-dependent DNA helicase/ssDNA
                     endodeoxyribonuclease DNA2"
                     /protein_id="NP_012034.1"
                     /db_xref="GI:6321958"
                     /db_xref="SGD:S000001207"
                     /db_xref="GeneID:856569"
                     /translation="MPGTPQKNKRSASISVSPAKKTEEKEIIQNDSKAILSKQTKRKK
                     KYAFAPINNLNGKNTKVSNASVLKSIAVSQVRNTSRTKDINKAVSKSVKQLPNSQVKP
                     KREMSNLSRHHDFTQDEDGPMEEVIWKYSPLQRDMSDKTTSAAEYSDDYEDVQNPSST
                     PIVPNRLKTVLSFTNIQVPNADVNQLIQENGNEQVRPKPAEISTRESLRNIDDILDDI
                     EGDLTIKPTITKFSDLPSSPIKAPNVEKKAEVNAEEVDKMDSTGDSNDGDDSLIDILT
                     QKYVEKRKSESQITIQGNTNQKSGAQESCGKNDNTKSRGEIEDHENVDNQAKTGNAFY
                     ENEEDSNCQRIKKNEKIEYNSSDEFSDDSLIELLNETQTQVEPNTIEQDLDKVEKMVS
                     DDLRIATDSTLSAYALRAKSGAPRDGVVRLVIVSLRSVELPKIGTQKILECIDGKGEQ
                     SSVVVRHPWVYLEFEVGDVIHIIEGKNIENKRLLSDDKNPKTQLANDNLLVLNPDVLF
                     SATSVGSSVGCLRRSILQMQFQDPRGEPSLVMTLGNIVHELLQDSIKYKLSHNKISME
                     IIIQKLDSLLETYSFSIIICNEEIQYVKELVMKEHAENILYFVNKFVSKSNYGCYTSI
                     SGTRRTQPISISNVIDIEENIWSPIYGLKGFLDATVEANVENNKKHIVPLEVKTGKSR
                     SVSYEVQGLIYTLLLNDRYEIPIEFFLLYFTRDKNMTKFPSVLHSIKHILMSRNRMSM
                     NFKHQLQEVFGQAQSRFELPPLLRDSSCDSCFIKESCMVLNKLLEDGTPEESGLVEGE
                     FEILTNHLSQNLANYKEFFTKYNDLITKEESSITCVNKELFLLDGSTRESRSGRCLSG
                     LVVSEVVEHEKTEGAYIYCFSRRRNDNNSQSMLSSQIAANDFVIISDEEGHFCLCQGR
                     VQFINPAKIGISVKRKLLNNRLLDKEKGVTTIQSVVESELEQSSLIATQNLVTYRIDK
                     NDIQQSLSLARFNLLSLFLPAVSPGVDIVDERSKLCRKTKRSDGGNEILRSLLVDNRA
                     PKFRDANDDPVIPYKLSKDTTLNLNQKEAIDKVMRAEDYALILGMPGTGKTTVIAEII
                     KILVSEGKRVLLTSYTHSAVDNILIKLRNTNISIMRLGMKHKVHPDTQKYVPNYASVK
                     SYNDYLSKINSTSVVATTCLGINDILFTLNEKDFDYVILDEASQISMPVALGPLRYGN
                     RFIMVGDHYQLPPLVKNDAARLGGLEESLFKTFCEKHPESVAELTLQYRMCGDIVTLS
                     NFLIYDNKLKCGNNEVFAQSLELPMPEALSRYRNESANSKQWLEDILEPTRKVVFLNY
                     DNCPDIIEQSEKDNITNHGEAELTLQCVEGMLLSGVPCEDIGVMTLYRAQLRLLKKIF
                     NKNVYDGLEILTADQFQGRDKKCIIISMVRRNSQLNGGALLKELRRVNVAMTRAKSKL
                     IIIGSKSTIGSVPEIKSFVNLLEERNWVYTMCKDALYKYKFPDRSNAIDEARKGCGKR
                     TGAKPITSKSKFVSDKPIIKEILQEYES"
     gene            complement(<429707..>436948)
                     /gene="PRP8"
                     /locus_tag="YHR165C"
                     /gene_synonym="DBF3; DNA39; RNA8; SLT21; USA2"
                     /db_xref="GeneID:856570"
     mRNA            complement(<429707..>436948)
                     /gene="PRP8"
                     /locus_tag="YHR165C"
                     /gene_synonym="DBF3; DNA39; RNA8; SLT21; USA2"
                     /product="U4/U6-U5 snRNP complex component PRP8"
                     /transcript_id="NM_001179296.1"
                     /db_xref="GI:296145542"
                     /db_xref="GeneID:856570"
     CDS             complement(429707..436948)
                     /gene="PRP8"
                     /locus_tag="YHR165C"
                     /gene_synonym="DBF3; DNA39; RNA8; SLT21; USA2"
                     /note="Component of U4/U6-U5 snRNP complex; involved in
                     second catalytic step of splicing; participates in
                     spliceosomal assembly through its interaction with U1
                     snRNA; largest and most evolutionarily conserved protein
                     of the spliceosome; mutations in its human ortholog,
                     PRPF8, cause Retinitis pigmentosa and missplicing in
                     Myelodysplastic syndrome."
                     /codon_start=1
                     /product="U4/U6-U5 snRNP complex component PRP8"
                     /protein_id="NP_012035.1"
                     /db_xref="GI:6321959"
                     /db_xref="SGD:S000001208"
                     /db_xref="GeneID:856570"
                     /translation="MSGLPPPPPGFEEDSDLALPPPPPPPPGYEIEELDNPMVPSSVN
                     EDTFLPPPPPPPSNFEINAEEIVDFTLPPPPPPPGLDELETKAEKKVELHGKRKLDIG
                     KDTFVTRKSRKRAKKMTKKAKRSNLYTPKAEMPPEHLRKIINTHSDMASKMYNTDKKA
                     FLGALKYLPHAILKLLENMPHPWEQAKEVKVLYHTSGAITFVNETPRVIEPVYTAQWS
                     ATWIAMRREKRDRTHFKRMRFPPFDDDEPPLSYEQHIENIEPLDPINLPLDSQDDEYV
                     KDWLYDSRPLEEDSKKVNGTSYKKWSFDLPEMSNLYRLSTPLRDEVTDKNYYYLFDKK
                     SFFNGKALNNAIPGGPKFEPLYPREEEEDYNEFNSIDRVIFRVPIRSEYKVAFPHLYN
                     SRPRSVRIPWYNNPVSCIIQNDEEYDTPALFFDPSLNPIPHFIDNNSSLNVSNTKENG
                     DFTLPEDFAPLLAEEEELILPNTKDAMSLYHSPFPFNRTKGKMVRAQDVALAKKWFLQ
                     HPDEEYPVKVKVSYQKLLKNYVLNELHPTLPTNHNKTKLLKSLKNTKYFQQTTIDWVE
                     AGLQLCRQGHNMLNLLIHRKGLTYLHLDYNFNLKPTKTLTTKERKKSRLGNSFHLMRE
                     LLKMMKLIVDTHVQFRLGNVDAFQLADGIHYILNHIGQLTGIYRYKYKVMHQIRACKD
                     LKHIIYYKFNKNLGKGPGCGFWQPAWRVWLNFLRGTIPLLERYIGNLITRQFEGRSNE
                     IVKTTTKQRLDAYYDLELRNSVMDDILEMMPESIRQKKARTILQHLSEAWRCWKANIP
                     WDVPGMPAPIKKIIERYIKSKADAWVSAAHYNRERIKRGAHVEKTMVKKNLGRLTRLW
                     IKNEQERQRQIQKNGPEITPEEATTIFSVMVEWLESRSFSPIPFPPLTYKNDTKILVL
                     ALEDLKDVYASKVRLNASEREELALIEEAYDNPHDTLNRIKKYLLTQRVFKPVDITMM
                     ENYQNISPVYSVDPLEKITDAYLDQYLWYEADQRKLFPNWIKPSDSEIPPLLVYKWTQ
                     GINNLSEIWDVSRGQSAVLLETTLGEMAEKIDFTLLNRLLRLIVDPNIADYITAKNNV
                     VINFKDMSHVNKYGLIRGLKFASFIFQYYGLVIDLLLLGQERATDLAGPANNPNEFMQ
                     FKSKEVEKAHPIRLYTRYLDRIYMLFHFEEDEGEELTDEYLAENPDPNFENSIGYNNR
                     KCWPKDSRMRLIRQDVNLGRAVFWEIQSRVPTSLTSIKWENAFVSVYSKNNPNLLFSM
                     CGFEVRILPRQRMEEVVSNDEGVWDLVDERTKQRTAKAYLKVSEEEIKKFDSRIRGIL
                     MASGSTTFTKVAAKWNTSLISLFTYFREAIVATEPLLDILVKGETRIQNRVKLGLNSK
                     MPTRFPPAVFYTPKELGGLGMISASHILIPASDLSWSKQTDTGITHFRAGMTHEDEKL
                     IPTIFRYITTWENEFLDSQRVWAEYATKRQEAIQQNRRLAFEELEGSWDRGIPRISTL
                     FQRDRHTLAYDRGHRIRREFKQYSLERNSPFWWTNSHHDGKLWNLNAYRTDVIQALGG
                     IETILEHTLFKGTGFNSWEGLFWEKASGFEDSMQFKKLTHAQRTGLSQIPNRRFTLWW
                     SPTINRANVYVGFLVQLDLTGIFLHGKIPTLKISLIQIFRAHLWQKIHESIVFDICQI
                     LDGELDVLQIESVTKETVHPRKSYKMNSSAADITMESVHEWEVSKPSLLHETNDSFKG
                     LITNKMWFDVQLRYGDYDSHDISRYVRAKFLDYTTDNVSMYPSPTGVMIGIDLAYNMY
                     DAYGNWFNGLKPLIQNSMRTIMKANPALYVLRERIRKGLQIYQSSVQEPFLNSSNYAE
                     LFNNDIKLFVDDTNVYRVTVHKTFEGNVATKAINGCIFTLNPKTGHLFLKIIHTSVWA
                     GQKRLSQLAKWKTAEEVSALVRSLPKEEQPKQIIVTRKAMLDPLEVHMLDFPNIAIRP
                     TELRLPFSAAMSIDKLSDVVMKATEPQMVLFNIYDDWLDRISSYTAFSRLTLLLRALK
                     TNEESAKMILLSDPTITIKSYHLWPSFTDEQWITIESQMRDLILTEYGRKYNVNISAL
                     TQTEIKDIILGQNIKAPSVKRQKMAELEAARSEKQNDEEAAGASTVMKTKTINAQGEE
                     IVVVASADYESQTFSSKNEWRKSAIANTLLYLRLKNIYVSADDFVEEQNVYVLPKNLL
                     KKFIEISDVKIQVAAFIYGMSAKDHPKVKEIKTVVLVPQLGHVGSVQISNIPDIGDLP
                     DTEGLELLGWIHTQTEELKFMAASEVATHSKLFADKKRDCIDISIFSTPGSVSLSAYN
                     LTDEGYQWGEENKDIMNVLSEGFEPTFSTHAQLLLSDRITGNFIIPSGNVWNYTFMGT
                     AFNQEGDYNFKYGIPLEFYNEMHRPVHFLQFSELAGDEELEAEQIDVFS"
     gene            complement(<437170..>439050)
                     /gene="CDC23"
                     /locus_tag="YHR166C"
                     /db_xref="GeneID:856571"
     mRNA            complement(<437170..>439050)
                     /gene="CDC23"
                     /locus_tag="YHR166C"
                     /product="anaphase promoting complex subunit CDC23"
                     /transcript_id="NM_001179297.1"
                     /db_xref="GI:296145543"
                     /db_xref="GeneID:856571"
     CDS             complement(437170..439050)
                     /gene="CDC23"
                     /locus_tag="YHR166C"
                     /note="Subunit of the Anaphase-Promoting Complex/Cyclosome
                     (APC/C); APC/C is a ubiquitin-protein ligase required for
                     degradation of anaphase inhibitors, including mitotic
                     cyclins, during the metaphase/anaphase transition"
                     /codon_start=1
                     /product="anaphase promoting complex subunit CDC23"
                     /protein_id="NP_012036.1"
                     /db_xref="GI:6321960"
                     /db_xref="SGD:S000001209"
                     /db_xref="GeneID:856571"
                     /translation="MNDDSQDKIIHDIRIQLRKAATELSRWKLYGSSKWAAEALAGLA
                     EAIDVDQTHSLADESPLRNKQGVPKQMFEIPQNGFGLSETEYDLYLLGSTLFDAKEFD
                     RCVFFLKDVTNPYLKFLKLYSKFLSWDKKSQESMENILTTGKFTDEMYRANKDGDGSG
                     NEDINQSGHQRANLKMVSNEHESQSNISSILKEINTFLESYEIKIDDDEADLGLALLY
                     YLRGVILKQEKNISKAMSSFLKSLSCYSFNWSCWLELMDCLQKVDDALLLNNYLYQNF
                     QFKFSENLGSQRTIEFNIMIKFFKLKVFEELNGQLEDYFEDLEFLLQVFPNFTFLKAY
                     NATISYNNLDYVTAESRFDDIVKQDPYRLNDLETYSNILYVMQKNSKLAYLAQFVSQI
                     DRFRPETCCIIANYYSARQEHEKSIMYFRRALTLDKKTTNAWTLMGHEFVELSNSHAA
                     IECYRRAVDICPRDFKAWFGLGQAYALLDMHLYSLYYFQKACTLKPWDRRIWQVLGEC
                     YSKTGNKVEAIKCYKRSIKASQTVDQNTSIYYRLAQLYEELEDLQECKKFMMKCVDVE
                     ELLEGIVTDETVKARLWLAIFEIKAGNYQLAYDYAMGVSSGTSQEIEEARMLARECRR
                     HM"
     gene            <439342..>440127
                     /gene="THP2"
                     /locus_tag="YHR167W"
                     /db_xref="GeneID:856572"
     mRNA            <439342..>440127
                     /gene="THP2"
                     /locus_tag="YHR167W"
                     /product="Thp2p"
                     /transcript_id="NM_001179298.1"
                     /db_xref="GI:296145544"
                     /db_xref="GeneID:856572"
     CDS             439342..440127
                     /gene="THP2"
                     /locus_tag="YHR167W"
                     /note="Subunit of the THO and TREX complexes; THO connects
                     transcription elongation and mitotic recombination, and
                     TREX is recruited to activated genes and couples
                     transcription to mRNA export; involved in telomere
                     maintenance"
                     /codon_start=1
                     /product="Thp2p"
                     /protein_id="NP_012037.1"
                     /db_xref="GI:6321961"
                     /db_xref="SGD:S000001210"
                     /db_xref="GeneID:856572"
                     /translation="MTKEEGRTYFESLCEEEQSLQESQTHLLNILDILSVLADPRSSD
                     DLLTESLKKLPDLHRELINSSIRLRYDKYQTREAQLLEDTKTGRDVAAGVQNPKSISE
                     YYSTFEHLNRDTLRYINLLKRLSVDLAKQVEVSDPSVTVYEMDKWVPSEKLQGILEQY
                     CAPDTDIRGVDAQIKNYLDQIKMARAKFGLENKYSLKERLSTLTKELNHWRKEWDDIE
                     MLMFGDDAHSMKKMIQKIDSLKSEINAPSESYPVDKEGDIVLE"
     gene            <440377..>441933
                     /gene="MTG2"
                     /locus_tag="YHR168W"
                     /db_xref="GeneID:856573"
     mRNA            <440377..>441933
                     /gene="MTG2"
                     /locus_tag="YHR168W"
                     /product="putative GTPase MTG2"
                     /transcript_id="NM_001179299.2"
                     /db_xref="GI:330443586"
                     /db_xref="GeneID:856573"
     CDS             440377..441933
                     /gene="MTG2"
                     /locus_tag="YHR168W"
                     /note="Putative GTPase; member of the Obg family;
                     peripheral protein of the mitochondrial inner membrane
                     that associates with the large ribosomal subunit; required
                     for mitochondrial translation, possibly via a role in
                     ribosome assembly"
                     /codon_start=1
                     /product="putative GTPase MTG2"
                     /protein_id="NP_012038.2"
                     /db_xref="GI:330443587"
                     /db_xref="SGD:S000001211"
                     /db_xref="GeneID:856573"
                     /translation="MSIAWSSVFKRELRLERFLPRVYSTKVPDNAPRAADNEQWLETL
                     RPITHPEQKKSDHDVSYTRHINVPLGEVTSVNYLQRYNKHKHSQGNFVDVRIVKCKSG
                     AGGSGAVSFFRDAGRSIGPPDGGDGGAGGSVYIQAVAGLGSLAKMKTTYTAEDGEAGA
                     ARQLDGMRGRDVLIQVPVGTVVKWCLPPQKVRELVEREMRKDNNATLRSILGSTAVNL
                     SVSSGSHRKKIQLYRHEMAESWLFKDKAKEYHENKDWFKDLHKKMEAYDHSLEQSELF
                     NDQFPLAGLDLNQPMTKPVCLLKGGQGGLGNMHFLTNLIRNPRFSKPGRNGLEQHFLF
                     ELKSIADLGLIGLPNAGKSTILNKISNAKPKIGHWQFTTLSPTIGTVSLGFGQDVFTV
                     ADIPGIIQGASLDKGMGLEFLRHIERSNGWVFVLDLSNKNPLNDLQLLIEEVGTLEKV
                     KTKNILIVCNKVDIDAEKSESFAKYLQVEKFSKSQEWDCVPISALREENIDVLKKKMF
                     KCARQSEFDK"
     gene            <442181..>443476
                     /gene="DBP8"
                     /locus_tag="YHR169W"
                     /db_xref="GeneID:856574"
     mRNA            <442181..>443476
                     /gene="DBP8"
                     /locus_tag="YHR169W"
                     /product="ATP-dependent RNA helicase DBP8"
                     /transcript_id="NM_001179300.1"
                     /db_xref="GI:296145546"
                     /db_xref="GeneID:856574"
     CDS             442181..443476
                     /gene="DBP8"
                     /locus_tag="YHR169W"
                     /EC_number="3.6.4.13"
                     /note="ATPase, putative RNA helicase of the DEAD-box
                     family; component of 90S preribosome complex involved in
                     production of 18S rRNA and assembly of 40S small ribosomal
                     subunit; ATPase activity stimulated by association with
                     Esf2p"
                     /codon_start=1
                     /product="ATP-dependent RNA helicase DBP8"
                     /protein_id="NP_012039.1"
                     /db_xref="GI:6321963"
                     /db_xref="SGD:S000001212"
                     /db_xref="GeneID:856574"
                     /translation="MADFKSLGLSKWLTESLRAMKITQPTAIQKACIPKILEGRDCIG
                     GAKTGSGKTIAFAGPMLTKWSEDPSGMFGVVLTPTRELAMQIAEQFTALGSSMNIRVS
                     VIVGGESIVQQALDLQRKPHFIIATPGRLAHHIMSSGDDTVGGLMRAKYLVLDEADIL
                     LTSTFADHLATCISALPPKDKRQTLLFTATITDQVKSLQNAPVQKGKPPLFAYQVESV
                     DNVAIPSTLKIEYILVPEHVKEAYLYQLLTCEEYENKTAIIFVNRTMTAEILRRTLKQ
                     LEVRVASLHSQMPQQERTNSLHRFRANAARILIATDVASRGLDIPTVELVVNYDIPSD
                     PDVFIHRSGRTARAGRIGDAISFVTQRDVSRIQAIEDRINKKMTETNKVHDTAVIRKA
                     LTKVTKAKRESLMAMQKENFGERKRQQKKKQNDGKSLRS"
     gene            <443828..>445384
                     /gene="NMD3"
                     /locus_tag="YHR170W"
                     /gene_synonym="SRC5"
                     /db_xref="GeneID:856575"
     mRNA            <443828..>445384
                     /gene="NMD3"
                     /locus_tag="YHR170W"
                     /gene_synonym="SRC5"
                     /product="ribosome-binding protein NMD3"
                     /transcript_id="NM_001179301.1"
                     /db_xref="GI:296145547"
                     /db_xref="GeneID:856575"
     CDS             443828..445384
                     /gene="NMD3"
                     /locus_tag="YHR170W"
                     /gene_synonym="SRC5"
                     /note="Protein involved in nuclear export of the large
                     ribosomal subunit; acts as a Crm1p-dependent adapter
                     protein for export of nascent ribosomal subunits through
                     the nuclear pore complex"
                     /codon_start=1
                     /product="ribosome-binding protein NMD3"
                     /protein_id="NP_012040.1"
                     /db_xref="GI:6321964"
                     /db_xref="SGD:S000001213"
                     /db_xref="GeneID:856575"
                     /translation="MEFTPIDPHQHQNAATLLCCNCGTPIDGSTGLVMCYDCIKLTVD
                     ITQGIPREANISFCRNCERFLQPPGQWIRAELESRELLAICLRRLKGLTKVRLVDASF
                     IWTEPHSRRIRIKLTVQGEAMTNTIIQQTFEVEYIVIAMQCPDCARSYTTNTWRATVQ
                     IRQKVPHKRTFLFLEQLILKHNAHVDTISISEAKDGLDFFYAQKNHAVKMIDFLNAVV
                     PIKHKKSEELISQDTHTGASTYKFSYSVEIVPICKDDLVVLPKKLAKSMGNISQFVLC
                     SKISNTVQFMDPTTLQTADLSPSVYWRAPFNALADVTQLVEFIVLDVDSTGISRGNRV
                     LADITVARTSDLGVNDQVYYVRSHLGGICHAGDSVMGYFIANSNYNSDLFDGLNIDYV
                     PDVVLVKKLYQRKSKKSRHWKLKRMAKEHKDIDASLDYNSRAQKQEMERAEKDYELFL
                     QELEEDAELRQSVNLYKNREANVPPEEHEMDEDEDEDAPQINIDELLDELDEMTLEDG
                     VENTPVESQQ"
     gene            <445713..>447605
                     /gene="ATG7"
                     /locus_tag="YHR171W"
                     /gene_synonym="APG11; APG7; CVT2"
                     /db_xref="GeneID:856576"
     mRNA            <445713..>447605
                     /gene="ATG7"
                     /locus_tag="YHR171W"
                     /gene_synonym="APG11; APG7; CVT2"
                     /product="Atg7p"
                     /transcript_id="NM_001179302.1"
                     /db_xref="GI:296145548"
                     /db_xref="GeneID:856576"
     CDS             445713..447605
                     /gene="ATG7"
                     /locus_tag="YHR171W"
                     /gene_synonym="APG11; APG7; CVT2"
                     /note="Autophagy-related protein and dual specificity
                     member of the E1 family; mediates the attachment of Atg12p
                     to Atg5p and Atg8p to phosphatidylethanolamine which are
                     required steps in autophagosome formation; E1 enzymes are
                     also known as ubiquitin-activating enzymes; involved in
                     methionine restriction extension of chronological lifespan
                     in an autophagy-dependent manner"
                     /codon_start=1
                     /product="Atg7p"
                     /protein_id="NP_012041.1"
                     /db_xref="GI:6321965"
                     /db_xref="SGD:S000001214"
                     /db_xref="GeneID:856576"
                     /translation="MSSERVLSYAPAFKSFLDTSFFQELSRLKLDVLKLDSTCQPLTV
                     NLDLHNIPKSADQVPLFLTNRSFEKHNNKRTNEVPLQGSIFNFNVLDEFKNLDKQLFL
                     HQRALECWEDGIKDINKCVSFVIISFADLKKYRFYYWLGVPCFQRPSSTVLHVRPEPS
                     LKGLFSKCQKWFDVNYSKWVCILDADDEIVNYDKCIIRKTKVLAIRDTSTMENVPSAL
                     TKNFLSVLQYDVPDLIDFKLLIIRQNEGSFALNATFASIDPQSSSSNPDMKVSGWERN
                     VQGKLAPRVVDLSSLLDPLKIADQSVDLNLKLMKWRILPDLNLDIIKNTKVLLLGAGT
                     LGCYVSRALIAWGVRKITFVDNGTVSYSNPVRQALYNFEDCGKPKAELAAASLKRIFP
                     LMDATGVKLSIPMIGHKLVNEEAQHKDFDRLRALIKEHDIIFLLVDSRESRWLPSLLS
                     NIENKTVINAALGFDSYLVMRHGNRDEQSSKQLGCYFCHDVVAPTDSLTDRTLDQMCT
                     VTRPGVAMMASSLAVELMTSLLQTKYSGSETTVLGDIPHQIRGFLHNFSILKLETPAY
                     EHCPACSPKVIEAFTDLGWEFVKKALEHPLYLEEISGLSVIKQEVERLGNDVFEWEDD
                     ESDEIA"
     rep_origin      447714..447795
                     /note="ARS820;
                     Autonomously Replicating Sequence"
                     /db_xref="SGD:S000118361"
     gene            <448335..>450806
                     /gene="SPC97"
                     /locus_tag="YHR172W"
                     /db_xref="GeneID:856577"
     mRNA            <448335..>450806
                     /gene="SPC97"
                     /locus_tag="YHR172W"
                     /product="Spc97p"
                     /transcript_id="NM_001179303.1"
                     /db_xref="GI:296145549"
                     /db_xref="GeneID:856577"
     CDS             448335..450806
                     /gene="SPC97"
                     /locus_tag="YHR172W"
                     /note="Component of the microtubule-nucleating Tub4p
                     (gamma-tubulin) complex; interacts with Spc110p at the
                     spindle pole body (SPB) inner plaque and with Spc72p at
                     the SPB outer plaque"
                     /codon_start=1
                     /product="Spc97p"
                     /protein_id="NP_012042.1"
                     /db_xref="GI:6321966"
                     /db_xref="SGD:S000001215"
                     /db_xref="GeneID:856577"
                     /translation="MEIKEVDDRAELLRYTNNIPLLGKLVNHQPLWSTNPKLKSFSLE
                     KISAPDQRRVQEALVVKDLLNVLIGLEGTYIRYFNDYEPSDPETPIEFKIAKKMDPSF
                     KTFSRRIVRYGKQYMILTRAYEKWSDTSFGMVLQRFAYEIRRFLEDVYLKTLVERLER
                     DFNKVPNFSIRELEQIINETEVNKQMELLYNIYEEIFREIEERRTNQSSQEDFNNFMD
                     SMKNESSLHLRLMVAFDTTVYPVPKGGAILKIFQQKILENLGDRSSVMFLKKLLNNIS
                     QDYCTMLYEWLTQGILNDPYQEFMTYDDLEGKTDNIFDTRDRAWDTQYFIRKDVLLRD
                     CDSEEDKNLLFKMLRTGILLKVVRASLQIPTIPSNSSDITIQEINDFADLMEGSNLEL
                     YVDKCYSRANEIFLKLFFQGYDLINVLKHLQQIFLGYQSGHNVLKFLTKNMGELTKHY
                     RNDNNANYDKLLQNFELERQSENPNNLMRQLLMIQFDTETLPQVLSHYLQIYPEVPEN
                     NSANDDSDPLMHANNFKNMNAILFDELSKERTGAYHGSNLELYTPKSAIYHLKFDINI
                     PYPLNIIISRTCMIKYQIILRYQLVLQYHSRLLDETWMDLNKTPSWKYRGYSHTVKRR
                     IVRATRVLHAKMNHFIKTIMEYFNQNVIDKEVYSLEKCYRNPTLAVAIQNELEGGLTN
                     IMTNRCLSDLIPLQLQIFDIVYKFCKFIKSMRAKLCQLDPVLYEKHKSGMMKTLNEGY
                     RTNNGGQEDVGYQEDAALELIQKLIEYISNASSIFRKCLINFTQELSTEKFDFYDSSS
                     VDAAGIERVLYSIVPPRSASASSQR"
     gene            complement(<450815..>451153)
                     /locus_tag="YHR173C"
                     /db_xref="GeneID:856578"
     mRNA            complement(<450815..>451153)
                     /locus_tag="YHR173C"
                     /product="hypothetical protein"
                     /transcript_id="NM_001270738.1"
                     /db_xref="GI:398364856"
                     /db_xref="GeneID:856578"
     CDS             complement(450815..451153)
                     /locus_tag="YHR173C"
                     /note="hypothetical protein; expressed at both mRNA and
                     protein levels"
                     /codon_start=1
                     /product="hypothetical protein"
                     /protein_id="NP_001257667.1"
                     /db_xref="GI:398364857"
                     /db_xref="SGD:S000001216"
                     /db_xref="GeneID:856578"
                     /translation="MLFFFIYAWCHLSHTILQPSTKIQMIVRSKPESNGEKKLMNHDE
                     PNDQYNQRNYPSEVYADLVSHFMNFAYGKVHESGLQKKGVRCVDVSISGCQFWNGIPL
                     SASWCTSLVT"
     gene            <451327..>452640
                     /gene="ENO2"
                     /locus_tag="YHR174W"
                     /db_xref="GeneID:856579"
     mRNA            <451327..>452640
                     /gene="ENO2"
                     /locus_tag="YHR174W"
                     /product="phosphopyruvate hydratase ENO2"
                     /transcript_id="NM_001179305.1"
                     /db_xref="GI:296145550"
                     /db_xref="GeneID:856579"
     CDS             451327..452640
                     /gene="ENO2"
                     /locus_tag="YHR174W"
                     /EC_number="4.2.1.11"
                     /note="Enolase II, a phosphopyruvate hydratase; catalyzes
                     conversion of 2-phosphoglycerate to phosphoenolpyruvate
                     during glycolysis and the reverse reaction during
                     gluconeogenesis; expression induced in response to
                     glucose; ENO2 has a paralog, ENO1, that arose from the
                     whole genome duplication"
                     /codon_start=1
                     /product="phosphopyruvate hydratase ENO2"
                     /protein_id="NP_012044.1"
                     /db_xref="GI:6321968"
                     /db_xref="SGD:S000001217"
                     /db_xref="GeneID:856579"
                     /translation="MAVSKVYARSVYDSRGNPTVEVELTTEKGVFRSIVPSGASTGVH
                     EALEMRDEDKSKWMGKGVMNAVNNVNNVIAAAFVKANLDVKDQKAVDDFLLSLDGTAN
                     KSKLGANAILGVSMAAARAAAAEKNVPLYQHLADLSKSKTSPYVLPVPFLNVLNGGSH
                     AGGALALQEFMIAPTGAKTFAEAMRIGSEVYHNLKSLTKKRYGASAGNVGDEGGVAPN
                     IQTAEEALDLIVDAIKAAGHDGKVKIGLDCASSEFFKDGKYDLDFKNPESDKSKWLTG
                     VELADMYHSLMKRYPIVSIEDPFAEDDWEAWSHFFKTAGIQIVADDLTVTNPARIATA
                     IEKKAADALLLKVNQIGTLSESIKAAQDSFAANWGVMVSHRSGETEDTFIADLVVGLR
                     TGQIKTGAPARSERLAKLNQLLRIEEELGDKAVYAGENFHHGDKL"
     gene            <452872..>453441
                     /gene="CTR2"
                     /locus_tag="YHR175W"
                     /db_xref="GeneID:856580"
     mRNA            <452872..>453441
                     /gene="CTR2"
                     /locus_tag="YHR175W"
                     /product="Ctr2p"
                     /transcript_id="NM_001179306.3"
                     /db_xref="GI:398364866"
                     /db_xref="GeneID:856580"
     CDS             452872..453441
                     /gene="CTR2"
                     /locus_tag="YHR175W"
                     /note="Putative low-affinity copper transporter of the
                     vacuolar membrane; mutation confers resistance to toxic
                     copper concentrations, while overexpression confers
                     resistance to copper starvation; regulated by
                     nonsense-mediated mRNA decay pathway"
                     /codon_start=1
                     /product="Ctr2p"
                     /protein_id="NP_012045.3"
                     /db_xref="GI:398364867"
                     /db_xref="SGD:S000001218"
                     /db_xref="GeneID:856580"
                     /translation="MDDKKTWSTVTLRTFNQLVTSSLIGYSKKMDSMNHKMEGNAGHD
                     HSDMHMGDGDDTCSMNMLFSWSYKNTCVVFEWWHIKTLPGLILSCLAIFGLAYLYEYL
                     KYCVHKRQLSQRVLLPNRSLTKINQADKVSNSILYGLQVGFSFMLMLVFMTYNGWLML
                     AVVCGAIWGNYSWCTSYSPEIDDSSLACH"
     gene            <453558..>453707
                     /locus_tag="YHR175W-A"
                     /db_xref="GeneID:1466530"
     mRNA            <453558..>453707
                     /locus_tag="YHR175W-A"
                     /product="hypothetical protein"
                     /transcript_id="NM_001184554.1"
                     /db_xref="GI:296145552"
                     /db_xref="GeneID:1466530"
     CDS             453558..453707
                     /locus_tag="YHR175W-A"
                     /note="hypothetical protein; identified by fungal homology
                     and RT-PCR"
                     /codon_start=1
                     /product="hypothetical protein"
                     /protein_id="NP_878090.1"
                     /db_xref="GI:33438808"
                     /db_xref="SGD:S000028553"
                     /db_xref="GeneID:1466530"
                     /translation="MINYVNITCIIFSTRTLLVFDTSLYIPPFMLSFIGYSLSNQNSP
                     LFLYH"
     gene            <454229..>455527
                     /gene="FMO1"
                     /locus_tag="YHR176W"
                     /db_xref="GeneID:856581"
     mRNA            <454229..>455527
                     /gene="FMO1"
                     /locus_tag="YHR176W"
                     /product="Fmo1p"
                     /transcript_id="NM_001179307.3"
                     /db_xref="GI:398364880"
                     /db_xref="GeneID:856581"
     CDS             454229..455527
                     /gene="FMO1"
                     /locus_tag="YHR176W"
                     /EC_number="1.14.13.-"
                     /note="Flavin-containing monooxygenase; localized to the
                     cytoplasmic face of the ER membrane; catalyzes oxidation
                     of biological thiols to maintain the ER redox buffer ratio
                     for correct folding of disulfide-bonded proteins"
                     /codon_start=1
                     /product="Fmo1p"
                     /protein_id="NP_012046.4"
                     /db_xref="GI:398364881"
                     /db_xref="SGD:S000001219"
                     /db_xref="GeneID:856581"
                     /translation="MTVNDKKRLAIIGGGPGGLAAARVFSQSLPNFEIEIFVKDYDIG
                     GVWHYPEQKSDGRVMYDHLETNISKKLMQFSGFPFEENVPLYPSRRNIWEYLKAYYKT
                     FIANKDAISIHFSTEVTYLKKKNSQWEITSKDELRTTKSDFDFVIVASGHYSVPKLPT
                     NIAGLDLWFDNKGAFHSKDFKNCEFAREKVVIVVGNGSSGQDIANQLTTVAKKVYNSI
                     KEPASNQLKAKLIETVQTIDSADWKNRSVTLSDGRVLQNIDYIIFATGYYYSFPFIEP
                     SVRLEVLGEGVTGDKHSSVNLHNLWEHMIYVKDPTLSFILTPQLVIPFPLSELQAAIM
                     VEVFCKSLPITTTFDSNACGTHNFPKGKDLEYYAELQELLNSIPRRVGHFEPVVWDDR
                     LIDLRNSSYTDKEERNVLLAEHAQALKKKKAPYFLPAPHT"
     gene            <456591..>457952
                     /locus_tag="YHR177W"
                     /db_xref="GeneID:856582"
     mRNA            <456591..>457952
                     /locus_tag="YHR177W"
                     /product="hypothetical protein"
                     /transcript_id="NM_001179308.1"
                     /db_xref="GI:296145554"
                     /db_xref="GeneID:856582"
     CDS             456591..457952
                     /locus_tag="YHR177W"
                     /note="Putative transcription factor containing a WOPR
                     domain; binds DNA in vitro; similar to C. albicans Wor1p
                     transcription factor that regulates white-opaque
                     switching; overexpression causes a cell cycle delay or
                     arrest"
                     /codon_start=1
                     /product="hypothetical protein"
                     /protein_id="NP_012047.1"
                     /db_xref="GI:6321971"
                     /db_xref="SGD:S000001220"
                     /db_xref="GeneID:856582"
                     /translation="MMDISPTCYGYIDDEQDLALVFQGVFNGNLRCIERRPYDAEKVE
                     LVNPGNIFVFNEEKSGIKRWTDGFSWSPSRISGKFLVYREYNRLGSTHDLPLHNVPEY
                     NIFERAHRKYFYTGLLKKTFSLKFNMDPTDSTKLETFHLIAYYTEKDIHQGSLRRPSE
                     NPFFHKFRPSQKLLDALQKVAVGNGRSNPSKNNERGRTKAHNYKTRRSLSSSPSYCDL
                     LSNYNNHPGNIPVRTAVQLPLTTFNNAPREMHQQQHRQQQQYLLPIDEQNKLPLPYMQ
                     HQPQPIGVYNPNYQPGLRRTVSQPMIFCNTYNTLPQQPTAAPYERRGVSPSVIYSSNT
                     LSPIPYQNIDPYSSRSGPECNHSKAPIAPTMMPPVHHILVHDYRQPKPVTDSINPPNV
                     NITTSTTNKNLDGIYILPAPRMNPPAQTQYQMIHAPDSMQHPPTFSKNNTSSNPKSHQ
                     YSK"
     gene            <459299..>461530
                     /gene="STB5"
                     /locus_tag="YHR178W"
                     /db_xref="GeneID:856583"
     mRNA            <459299..>461530
                     /gene="STB5"
                     /locus_tag="YHR178W"
                     /product="Stb5p"
                     /transcript_id="NM_001179309.3"
                     /db_xref="GI:398364890"
                     /db_xref="GeneID:856583"
     CDS             459299..461530
                     /gene="STB5"
                     /locus_tag="YHR178W"
                     /note="Transcription factor; involved in regulating
                     multidrug resistance and oxidative stress response; forms
                     a heterodimer with Pdr1p; contains a Zn(II)2Cys6 zinc
                     finger domain that interacts with a pleiotropic drug
                     resistance element in vitro"
                     /codon_start=1
                     /product="Stb5p"
                     /protein_id="NP_012048.3"
                     /db_xref="GI:398364891"
                     /db_xref="SGD:S000001221"
                     /db_xref="GeneID:856583"
                     /translation="MDGPNFAHQGGRSQRTTELYSCARCRKLKKKCGKQIPTCANCDK
                     NGAHCSYPGRAPRRTKKELADAMLRGEYVPVKRNKKVGKSPLSTKSMPNSSSPLSANG
                     AITPGFSPYENDDAHKMKQLKPSDPINLVMGASPNSSEGVSSLISVLTSLNDNSNPSS
                     HLSSNENSMIPSRSLPASVQQSSTTSSFGGYNTPSPLISSHVPANAQAVPLQNNNRNT
                     SNGDNGSNVNHDNNNGSTNTPQLSLTPYANNSAPNGKFDSVPVDASSIEFETMSCCFK
                     GGRTTSWVREDGSFKSIDRSLLDRFIAAYFKHNHRLFPMIDKIAFLNDAATITDFERL
                     YDNKNYPDSFVFKVYMIMAIGCTTLQRAGMVSQDEECLSEHLAFLAMKKFRSVIILQD
                     IETVRCLLLLGIYSFFEPKGSSSWTISGIIMRLTIGLGLNRELTAKKLKSMSALEAEA
                     RYRVFWSAYCFERLVCTSLGRISGIDDEDITVPLPRALYVDERDDLEMTKLMISLRKM
                     GGRIYKQVHSVSAGRQKLTIEQKQEIISGLRKELDEIYSRESERRKLKKSQMDQVERE
                     NNSTTNVISFHSSEIWLAMRYSQLQILLYRPSALMPKPPIDSLSTLGEFCLQAWKHTY
                     TLYKKRLLPLNWITLFRTLTICNTILYCLCQWSIDLIESKIEIQQCVEILRHFGERWI
                     FAMRCADVFQNISNTILDISLSHGKVPNMDQLTRELFGASDSYQDILDENNVDVSWVD
                     KLV"
     gene            <462502..>463704
                     /gene="OYE2"
                     /locus_tag="YHR179W"
                     /db_xref="GeneID:856584"
     mRNA            <462502..>463704
                     /gene="OYE2"
                     /locus_tag="YHR179W"
                     /product="Oye2p"
                     /transcript_id="NM_001179310.1"
                     /db_xref="GI:296145556"
                     /db_xref="GeneID:856584"
     CDS             462502..463704
                     /gene="OYE2"
                     /locus_tag="YHR179W"
                     /EC_number="1.6.99.1"
                     /note="Conserved NADPH oxidoreductase containing flavin
                     mononucleotide (FMN); responsible for geraniol reduction
                     into citronellol during fermentation; homologous to Oye3p
                     with different ligand binding and catalytic properties;
                     may be involved in sterol metabolism, oxidative stress
                     response, and programmed cell death; protein abundance
                     increases in response to DNA replication stress"
                     /codon_start=1
                     /product="Oye2p"
                     /protein_id="NP_012049.1"
                     /db_xref="GI:6321973"
                     /db_xref="SGD:S000001222"
                     /db_xref="GeneID:856584"
                     /translation="MPFVKDFKPQALGDTNLFKPIKIGNNELLHRAVIPPLTRMRAQH
                     PGNIPNRDWAVEYYAQRAQRPGTLIITEGTFPSPQSGGYDNAPGIWSEEQIKEWTKIF
                     KAIHENKSFAWVQLWVLGWAAFPDTLARDGLRYDSASDNVYMNAEQEEKAKKANNPQH
                     SITKDEIKQYVKEYVQAAKNSIAAGADGVEIHSANGYLLNQFLDPHSNNRTDEYGGSI
                     ENRARFTLEVVDAVVDAIGPEKVGLRLSPYGVFNSMSGGAETGIVAQYAYVLGELERR
                     AKAGKRLAFVHLVEPRVTNPFLTEGEGEYNGGSNKFAYSIWKGPIIRAGNFALHPEVV
                     REEVKDPRTLIGYGRFFISNPDLVDRLEKGLPLNKYDRDTFYKMSAEGYIDYPTYEEA
                     LKLGWDKN"
     LTR             complement(463920..464147)
                     /note="Ty1 LTR"
                     /db_xref="SGD:S000006999"
     LTR             466549..466863
                     /note="Ty1 LTR"
                     /db_xref="SGD:S000007009"
     LTR             complement(466884..466975)
                     /note="Ty3 LTR"
                     /db_xref="SGD:S000007004"
     gene            466990..467061
                     /locus_tag="tT(UGU)H"
                     /db_xref="GeneID:856586"
     tRNA            466990..467061
                     /locus_tag="tT(UGU)H"
                     /product="tRNA-Thr"
                     /note="Threonine tRNA (tRNA-Thr), predicted by tRNAscan-SE
                     analysis"
                     /db_xref="SGD:S000006751"
                     /db_xref="GeneID:856586"
     gene            <467228..>467914
                     /gene="SVP26"
                     /locus_tag="YHR181W"
                     /gene_synonym="ERV26"
                     /db_xref="GeneID:856587"
     mRNA            <467228..>467914
                     /gene="SVP26"
                     /locus_tag="YHR181W"
                     /gene_synonym="ERV26"
                     /product="Svp26p"
                     /transcript_id="NM_001179312.3"
                     /db_xref="GI:398364906"
                     /db_xref="GeneID:856587"
     CDS             467228..467914
                     /gene="SVP26"
                     /locus_tag="YHR181W"
                     /gene_synonym="ERV26"
                     /note="Integral membrane protein of the early Golgi
                     apparatus and ER; involved in COP II vesicle transport;
                     may also function to promote retention of proteins in the
                     early Golgi compartment"
                     /codon_start=1
                     /product="Svp26p"
                     /protein_id="NP_012051.3"
                     /db_xref="GI:398364907"
                     /db_xref="SGD:S000001224"
                     /db_xref="GeneID:856587"
                     /translation="MLLELISYAGTVSGFLFLTLSIASGLYYISELVEEHTEPTRRFL
                     TRAIYGIILILILLLLLDGFPFKLTLFSIACYIVYYQNLKSFPFISLTSPTFLLSCVC
                     VVLNHYFWFKYFNDTEVPPQFKFDPNYIPRRRASFAEVASFFGICVWFIPFALFVSLS
                     AGDYVLPTTSEQHMAKKNDDITTNNQPKFRKRAVGLARVVINSVRKYIYSLARVFGYE
                     IEPDFDRLAV"
     gene            <468219..>470576
                     /locus_tag="YHR182W"
                     /db_xref="GeneID:856588"
     mRNA            <468219..>470576
                     /locus_tag="YHR182W"
                     /product="hypothetical protein"
                     /transcript_id="NM_001179313.1"
                     /db_xref="GI:296145558"
                     /db_xref="GeneID:856588"
     CDS             468219..470576
                     /locus_tag="YHR182W"
                     /note="hypothetical protein; green fluorescent protein
                     (GFP)-fusion protein localizes to the cell periphery and
                     cytoplasm; relocalizes from bud neck to cytoplasm upon DNA
                     replication stress"
                     /codon_start=1
                     /product="hypothetical protein"
                     /protein_id="NP_012052.1"
                     /db_xref="GI:6321976"
                     /db_xref="SGD:S000001225"
                     /db_xref="GeneID:856588"
                     /translation="MSVKEHNEEDIIGDELQNSRQLSIDCDSVKISLRNTYWTKDYTT
                     GIKLFIKHMKRENDLLIKDIKFYNDFVNKFWKPTLNNLQKMEATNSMNSRLLEVMSKQ
                     FNIISTEQVERDCKIPLQELRDLNESFLREAENDLSSRYSAYIKDLVAAKEALIGCEK
                     RVQSIYKLKKANTPVENSSSVFDNGKDSAPLTRLNFVCEFPYTLDERLKFEDCDQFMS
                     FLQTLKGKVILEKSVFSVPGLSNQSFQGRSLIKELKKLEPRLNLSLFNIDRIGNEFIQ
                     LGIIQEYSLSFYSSKVSQFDQEKYYYWNSEVLATQESNGNAGNRKKKSYGELTHSDNE
                     HEEKSNVSSIKTSISDWIRKVSQHDNDDCDAAGSTDMNKNEWKSLKQQLESSQDIFFS
                     KCCQLEYSKVQLEKTIYDYCKNYSKMEDGIKRALESSNMMFQQKCEKFTDSPVCSLQE
                     AQLPQETANADVRGFFLRDNGIPFRRWNILEASDPVDACKEISIKSEKFFCGSEINNE
                     LAALDTLGAIKIILRQIEKEPNANKVIQSWHRDIDFVRVSNLKRDLLGEFKGSKTTEN
                     TNSIITAHFFENSHSYVTNDLVGLIKLWLLELPDSLIPSNHYDDLIKAEKSLTSLCEQ
                     FPTSSLRFLQELANHFQLINSKYSLPPQTIQDLFRDNSDIDIPLAHHFVRRTGLQNPI
                     DIKILSPTLSTFFINERTVETLQTLIANRITTATTATLTEPPTIIIKDTTAPIHSTPK
                     PPPNDKDGHFIPRPFKTSSTPTTPERPKRKSGLFLPINVNDVPST"
     gene            <470960..>472429
                     /gene="GND1"
                     /locus_tag="YHR183W"
                     /db_xref="GeneID:856589"
     mRNA            <470960..>472429
                     /gene="GND1"
                     /locus_tag="YHR183W"
                     /product="phosphogluconate dehydrogenase (decarboxylating)
                     GND1"
                     /transcript_id="NM_001179314.3"
                     /db_xref="GI:398364912"
                     /db_xref="GeneID:856589"
     CDS             470960..472429
                     /gene="GND1"
                     /locus_tag="YHR183W"
                     /EC_number="1.1.1.44"
                     /note="6-phosphogluconate dehydrogenase (decarboxylating);
                     catalyzes an NADPH regenerating reaction in the pentose
                     phosphate pathway; required for growth on
                     D-glucono-delta-lactone and adaptation to oxidative
                     stress; GND1 has a paralog, GND2, that arose from the
                     whole genome duplication"
                     /codon_start=1
                     /product="phosphogluconate dehydrogenase (decarboxylating)
                     GND1"
                     /protein_id="NP_012053.3"
                     /db_xref="GI:398364913"
                     /db_xref="SGD:S000001226"
                     /db_xref="GeneID:856589"
                     /translation="MSADFGLIGLAVMGQNLILNAADHGFTVCAYNRTQSKVDHFLAN
                     EAKGKSIIGATSIEDFISKLKRPRKVMLLVKAGAPVDALINQIVPLLEKGDIIIDGGN
                     SHFPDSNRRYEELKKKGILFVGSGVSGGEEGARYGPSLMPGGSEEAWPHIKNIFQSIS
                     AKSDGEPCCEWVGPAGAGHYVKMVHNGIEYGDMQLICEAYDIMKRLGGFTDKEISDVF
                     AKWNNGVLDSFLVEITRDILKFDDVDGKPLVEKIMDTAGQKGTGKWTAINALDLGMPV
                     TLIGEAVFARCLSALKNERIRASKVLPGPEVPKDAVKDREQFVDDLEQALYASKIISY
                     AQGFMLIREAAATYGWKLNNPAIALMWRGGCIIRSVFLGQITKAYREEPDLENLLFNK
                     FFADAVTKAQSGWRKSIALATTYGIPTPAFSTALSFYDGYRSERLPANLLQAQRDYFG
                     AHTFRVLPECASDNLPVDKDIHINWTGHGGNVSSSTYQA"
     gene            <472744..>474459
                     /gene="SSP1"
                     /locus_tag="YHR184W"
                     /gene_synonym="SPO3"
                     /db_xref="GeneID:856590"
     mRNA            <472744..>474459
                     /gene="SSP1"
                     /locus_tag="YHR184W"
                     /gene_synonym="SPO3"
                     /product="Ssp1p"
                     /transcript_id="NM_001179315.1"
                     /db_xref="GI:296145560"
                     /db_xref="GeneID:856590"
     CDS             472744..474459
                     /gene="SSP1"
                     /locus_tag="YHR184W"
                     /gene_synonym="SPO3"
                     /note="Protein involved in the control of meiotic nuclear
                     division; also involved in the coordination of meiosis
                     with spore formation; transcription is induced midway
                     through meiosis"
                     /codon_start=1
                     /product="Ssp1p"
                     /protein_id="NP_012054.1"
                     /db_xref="GI:6321978"
                     /db_xref="SGD:S000001227"
                     /db_xref="GeneID:856590"
                     /translation="MRSSGTYENDPSGEITSTSPKQSKQKKPTKFRERMRRWLQNGKN
                     NNHQGEEDVPEIFNKNFYPQTGMTAFNNNDNGEVQDVTNNFFLPSEDESGPVQSSVKT
                     FLTGNNDEDSNFQQNQNPKQKSELPKSPYRQKPTQEIALLKDLFVTNKYDDPYLNSST
                     RFGNITSTFPSSLSLRTVTLQTIKKRIDCISAKKKEVWKTEEKFLKDILMWLQSSNFE
                     DPDTISLIHEIEKIFEEDIHFEQNVSDCLKEISNNFEYICMRETQLINEGNILKNDLK
                     KYAKAREHKGEKHEDTEVLREKVISSQKSFDVTKRHYKHAISITTRQLFMNLAFEYYE
                     NCSDMKDISRKYLQESLSTLQTIDTLSFSEELEKIRKRRFDKFWAKTNPDPTNNIQKF
                     VNMRTGVAGFNDSLMNHLYGKLSFGVAPVEEELQNSQPEHTDVPENVWNEVLSDYNSM
                     DGNPITSNKFLSAKELEPDQLVELLAQEKEEKEAKNISSSTAEVPSISQPEIKKENLE
                     SNDSLILRSTKRNVNVNAASLRNLSIKKTQVKPESASEESKVLAAALNDAKQNLDENV
                     WRTPI"
     gene            complement(<474627..>475340)
                     /gene="PFS1"
                     /locus_tag="YHR185C"
                     /gene_synonym="ADY1"
                     /db_xref="GeneID:856591"
     mRNA            complement(<474627..>475340)
                     /gene="PFS1"
                     /locus_tag="YHR185C"
                     /gene_synonym="ADY1"
                     /product="Pfs1p"
                     /transcript_id="NM_001179316.3"
                     /db_xref="GI:398364924"
                     /db_xref="GeneID:856591"
     CDS             complement(474627..475340)
                     /gene="PFS1"
                     /locus_tag="YHR185C"
                     /gene_synonym="ADY1"
                     /note="Sporulation protein required for prospore membrane
                     formation; required for prospore membrane formation at
                     selected spindle poles; ensures functionality of all four
                     spindle pole bodies during meiosis II; not required for
                     meiotic recombination or meiotic chromosome segregation"
                     /codon_start=1
                     /product="Pfs1p"
                     /protein_id="NP_012055.3"
                     /db_xref="GI:398364925"
                     /db_xref="SGD:S000001228"
                     /db_xref="GeneID:856591"
                     /translation="MNQGYTQLSAPELKETKTSKLNKMNNFRSSPIAEIINKIPPDCG
                     KIQNTTFPEFNPALRRRQHEQWPAYEKPIRVTDSMSPQLSSINCLPNLYPHGTLPLPN
                     PYLSYLNHIEKVNCQDVKFSNWSVLHNSNNGFEIPTYFSPRTTQNMPCSEKVESWLER
                     LPIFVGFDGYLFTNCFDYEYMLDWEETEFTFEKTSCMETDYSKALTDTDIIYIQEKKI
                     EALIRNQYLKEYEFSQKDF"
     gene            complement(475706..475778)
                     /locus_tag="tV(CAC)H"
                     /db_xref="GeneID:856592"
     tRNA            complement(475706..475778)
                     /locus_tag="tV(CAC)H"
                     /product="tRNA-Val"
                     /note="Valine tRNA (tRNA-Val), predicted by tRNAscan-SE
                     analysis"
                     /db_xref="SGD:S000006768"
                     /db_xref="GeneID:856592"
     gene            complement(<475999..>480672)
                     /gene="KOG1"
                     /locus_tag="YHR186C"
                     /gene_synonym="LAS24"
                     /db_xref="GeneID:856593"
     mRNA            complement(<475999..>480672)
                     /gene="KOG1"
                     /locus_tag="YHR186C"
                     /gene_synonym="LAS24"
                     /product="Kog1p"
                     /transcript_id="NM_001179317.1"
                     /db_xref="GI:296145562"
                     /db_xref="GeneID:856593"
     CDS             complement(475999..480672)
                     /gene="KOG1"
                     /locus_tag="YHR186C"
                     /gene_synonym="LAS24"
                     /note="Subunit of TORC1; TORC1 is a rapamycin-sensitive
                     complex involved in growth control that contains Tor1p or
                     Tor2p, Lst8p and Tco89p; contains four HEAT repeats and
                     seven WD-40 repeats; may act as a scaffold protein to
                     couple TOR and its effectors"
                     /codon_start=1
                     /product="Kog1p"
                     /protein_id="NP_012056.1"
                     /db_xref="GI:6321980"
                     /db_xref="SGD:S000001229"
                     /db_xref="GeneID:856593"
                     /translation="MPEIYGPQPLKPLNTVMRHGFEEQYQSDQLLQSLANDFIFYFDD
                     KRHKTNGNPIPEEDKQRDVNRYYQPITDWKIMKDRQKTVSAALLLCLNLGVDPPDVMK
                     THPCARVEAWVDPLNFQDSKKAIEQIGKNLQAQYETLSLRTRYKQSLDPCVEDVKRFC
                     NSLRRTSKEDRILFHYNGHGVPKPTKSGEIWVFNRGYTQYIPVSLYDLQTWLGAPCIF
                     VYDCNSAENILINFQKFVQKRIKDDEEGNHDVAAPSPTSAYQDCFQLASCTSDELLLM
                     SPELPADLFSCCLTCPIEISIRIFLMQSPLKDSKYKIFFENSTSNQPFGDSKNSFKSK
                     IPNVNIPGMLSDRRTPLGELNWIFTAITDTIAWTSLPRPLFKKLFRHDLMIAALFRNF
                     LLAKRIMPWYNCHPVSDPELPDSITTHPMWKSWDLAMDEVLTKIVIDLKNAPPATALE
                     SQMILQQQETLQNGGSSKSNAQDTKAGSIQTQSRFAVANLSTMSLVNNPALQSRKSIS
                     LQSSQQQLQQQQQQQQQFTGFFEQNLTAFELWLKYASNVRHPPEQLPIVLQVLLSQVH
                     RIRALVLLSRFLDLGPWAVYLSLSIGIFPYVLKLLQSPAPELKPILVFIWARIMSIDY
                     KNTQSELIKEKGYMYFVTVLVPDWGVNGMSATNGSAMINSGNPLTMTASQNINGPSSR
                     YYERQQGNRTSNLGHNNLPFYHSNDTTDEQKAMAVFVLASFVRNFPLGQKNCFSLELV
                     NKLCFYIDNSEIPLLRQWCVILLGLLFADNPLNRFVCMNTGAVEILLKSLKDPVPEVR
                     TASIFALKHFISGFQDAEVILRLQQEFEEQYQQLHSQLQHLQNQSHLQQQQSQQQQQH
                     LEQQQMKIEKQIRHCQVMQNQLEVIDLRKLKRQEIGNLISILPLINDGSSLVRKELVV
                     YFSHIVSRYSNFFIVVVFNDLLEEIKLLEKSDINTRNTSDKYSVSQGSIFYTVWKSLL
                     ILAEDPFLENKELSKQVIDYILLELSAHKELGGPFAVMEKFLLKRSSKAHQTGKFGFN
                     SSQVQFVKSSLRSFSPNERVDNNAFKKEQQQHDPKISHPMRTSLAKLFQSLGFSESNS
                     DSDTQSSNTSMKSHTSKKGPSGLYLLNGNNNIYPTAETPRFRKHTEPLQLPLNSSFLD
                     YSREYFQEPQMKKQEADEPGSVEYNARLWRRNRNETIIQETQGEKKLSIYGNWSKKLI
                     SLNNKSQPKLMKFAQFEDQLITADDRSTITVFDWEKGKTLSKFSNGTPFGTKVTDLKL
                     INEDDSALLLTGSSDGVIKIYRDYQDVDTFKIVSAWRGLTDMLLTPRSTGLLTEWLQI
                     RGSLLTTGDVKVIRVWDAHTETVEVDIPAKTSSLITSLTADQLAGNIFVAGFADGSLR
                     VYDRRLDPRDSMIRRWRAGNDKQGVWINNVHLQRGGYRELVSGATNGVVELWDIRSED
                     PVESFVDQNVTSQYGSQQKPTTMTCMQVHEHAPIIATGTKQIKIWTTSGDLLNSFKNS
                     HNNGVTSTLAATGIPKSLSYSSTSDAFLSSMAFHPHRMMIAATNSHDSIVNIYKCEDE
                     RIDYF"
     gene            <480990..>481919
                     /gene="IKI1"
                     /locus_tag="YHR187W"
                     /gene_synonym="ELP5; HAP2; TOT5"
                     /db_xref="GeneID:856594"
     mRNA            <480990..>481919
                     /gene="IKI1"
                     /locus_tag="YHR187W"
                     /gene_synonym="ELP5; HAP2; TOT5"
                     /product="Elongator subunit IKI1"
                     /transcript_id="NM_001179318.3"
                     /db_xref="GI:398364942"
                     /db_xref="GeneID:856594"
     CDS             480990..481919
                     /gene="IKI1"
                     /locus_tag="YHR187W"
                     /gene_synonym="ELP5; HAP2; TOT5"
                     /note="Subunit of hexameric RecA-like ATPase Elp456
                     Elongator subcomplex; which is required for modification
                     of wobble nucleosides in tRNA; iki1 mutations confer
                     resistance to the K. lactis toxin zymocin"
                     /codon_start=1
                     /product="Elongator subunit IKI1"
                     /protein_id="NP_012057.3"
                     /db_xref="GI:398364943"
                     /db_xref="SGD:S000001230"
                     /db_xref="GeneID:856594"
                     /translation="MASSSHNPVILLKRILSLTESSPFILCLDSIAQTSYKLIQEFVH
                     QSKSKGNEYPIVYISFETVNKPSYCTQFIDATQMDFVHLVKQIISYLPAATATQAKKH
                     MVIIDSLNYISTEYITRFLSEIASPHCTMVATYHKDIKDENRTVIPDWNNNYPDKLTL
                     LQFMATTIVDIDVVLTGTLDTEEVSELLNEFRIPRGLNNDIFQLRLVNKRKSGRSLEY
                     DFIVNSNTHEYELLSTTKQEEESSSNGLETPEMLQGLTTFNLGTSNKQKLAKDQVALP
                     FLEAQSFGQGGAIVYEYEKDDDYDEEDPYEDPF"
     gene            complement(<482005..>483837)
                     /gene="GPI16"
                     /locus_tag="YHR188C"
                     /db_xref="GeneID:856595"
     mRNA            complement(<482005..>483837)
                     /gene="GPI16"
                     /locus_tag="YHR188C"
                     /product="Gpi16p"
                     /transcript_id="NM_001179319.1"
                     /db_xref="GI:296145564"
                     /db_xref="GeneID:856595"
     CDS             complement(482005..483837)
                     /gene="GPI16"
                     /locus_tag="YHR188C"
                     /note="Subunit of the glycosylphosphatidylinositol
                     transamidase complex; transmembrane protein; adds GPIs to
                     newly synthesized proteins; human PIG-Tp homolog"
                     /codon_start=1
                     /product="Gpi16p"
                     /protein_id="NP_012058.1"
                     /db_xref="GI:6321982"
                     /db_xref="SGD:S000001231"
                     /db_xref="GeneID:856595"
                     /translation="MILTLAYFMLGTLLLGVFAEDTVSQIGINDSLWYPYDEALVLKP
                     LPNNDLLLSFAFQLQSEPFDPAVSSMSYDAYEHYTTFPRAIPPLLESTATRQFHLRFT
                     RGFWDALSWGQLPHAGKEAGASGVELWSQVQAMDQEQAFHNWKKLSNSLSGLFCSSLN
                     FIDESRTTFPRRSYASDIGAPLFNSTEKLYLMRASLPNEPICTENLTPFIKLLPTRGK
                     SGLTSLLDGHKLFDSLWNSISLDIATICSEDEDALCHYEMDARIEMVTHVPSALARGE
                     RPIPKPLDGNTLRCDTDKPFDSYQCFPLPEPSQTHFKLSQLFARPINNGNLFANRPTR
                     ICAEVDRSTWTAFLSVDDTIFSTHDNCFDLSNDQNEGGSGYDFILESTDTTKVTPIVP
                     VPIHVSRSLTGNGQDRGGMRIVFHNDNDTPVKLIYFESLPWFMRVYLSSLQITSTTSP
                     QLQENDIILDKYYLQAADRKRPGHLEFTMLIPANTDIVMTYQFDKALLQFAEYPPDAN
                     HGFEIDAAVITVLSLESSSSLYEMRTSTLLLSLSTPDFSMPYNVIILTSTIMGLIFGM
                     LYNLMVKRMVTVEEADKITLQSGLKYKLLKLKEKFLGKKKTKTD"
     gene            <484028..>484600
                     /gene="PTH1"
                     /locus_tag="YHR189W"
                     /db_xref="GeneID:856596"
     mRNA            <484028..>484600
                     /gene="PTH1"
                     /locus_tag="YHR189W"
                     /product="Pth1p"
                     /transcript_id="NM_001179320.3"
                     /db_xref="GI:398364954"
                     /db_xref="GeneID:856596"
     CDS             484028..484600
                     /gene="PTH1"
                     /locus_tag="YHR189W"
                     /EC_number="3.1.1.29"
                     /note="One of two mitochondrially-localized peptidyl-tRNA
                     hydrolases; dispensable for respiratory growth on rich
                     medium, but required for respiratory growth on minimal
                     medium; see also PTH2"
                     /codon_start=1
                     /product="Pth1p"
                     /protein_id="NP_012059.3"
                     /db_xref="GI:398364955"
                     /db_xref="SGD:S000001232"
                     /db_xref="GeneID:856596"
                     /translation="MSGKWRLVLTGIGNPEPQYAGTRHNVGLYMLELLRKRLGLQGRT
                     YSPVPNTGGKVHYIEDEHCTILRSDGQYMNLSGEQVCKVWARYAKYQARHVVIHDELS
                     VACGKVQLRAPSTSIRGHNGLRSLLKCSGGRVPFAKLAIGIGREPGSRSRDPASVSRW
                     VLGALTPQELQTLLTQSEPAAWRALTQYIS"
     gene            <484845..>486179
                     /gene="ERG9"
                     /locus_tag="YHR190W"
                     /db_xref="GeneID:856597"
     mRNA            <484845..>486179
                     /gene="ERG9"
                     /locus_tag="YHR190W"
                     /product="bifunctional farnesyl-diphosphate
                     farnesyltransferase/squalene synthase"
                     /transcript_id="NM_001179321.1"
                     /db_xref="GI:296145566"
                     /db_xref="GeneID:856597"
     CDS             484845..486179
                     /gene="ERG9"
                     /locus_tag="YHR190W"
                     /EC_number="2.5.1.21"
                     /note="Farnesyl-diphosphate farnesyl transferase (squalene
                     synthase); joins two farnesyl pyrophosphate moieties to
                     form squalene in the sterol biosynthesis pathway"
                     /codon_start=1
                     /product="bifunctional farnesyl-diphosphate
                     farnesyltransferase/squalene synthase"
                     /protein_id="NP_012060.1"
                     /db_xref="GI:6321984"
                     /db_xref="SGD:S000001233"
                     /db_xref="GeneID:856597"
                     /translation="MGKLLQLALHPVEMKAALKLKFCRTPLFSIYDQSTSPYLLHCFE
                     LLNLTSRSFAAVIRELHPELRNCVTLFYLILRALDTIEDDMSIEHDLKIDLLRHFHEK
                     LLLTKWSFDGNAPDVKDRAVLTDFESILIEFHKLKPEYQEVIKEITEKMGNGMADYIL
                     DENYNLNGLQTVHDYDVYCHYVAGLVGDGLTRLIVIAKFANESLYSNEQLYESMGLFL
                     QKTNIIRDYNEDLVDGRSFWPKEIWSQYAPQLKDFMKPENEQLGLDCINHLVLNALSH
                     VIDVLTYLAGIHEQSTFQFCAIPQVMAIATLALVFNNREVLHGNVKIRKGTTCYLILK
                     SRTLRGCVEIFDYYLRDIKSKLAVQDPNFLKLNIQISKIEQFMEEMYQDKLPPNVKPN
                     ETPIFLKVKERSRYDDELVPTQQEEEYKFNMVLSIILSVLLGFYYIYTLHRA"
     gene            complement(<486230..>486631)
                     /gene="CTF8"
                     /locus_tag="YHR191C"
                     /db_xref="GeneID:856598"
     mRNA            complement(<486230..>486631)
                     /gene="CTF8"
                     /locus_tag="YHR191C"
                     /product="Ctf8p"
                     /transcript_id="NM_001179322.3"
                     /db_xref="GI:398364968"
                     /db_xref="GeneID:856598"
     CDS             complement(486230..486631)
                     /gene="CTF8"
                     /locus_tag="YHR191C"
                     /note="Subunit of a complex with Ctf18p; shares some
                     subunits with Replication Factor C; required for sister
                     chromatid cohesion"
                     /codon_start=1
                     /product="Ctf8p"
                     /protein_id="NP_012061.3"
                     /db_xref="GI:398364969"
                     /db_xref="SGD:S000001234"
                     /db_xref="GeneID:856598"
                     /translation="MPSVDIDASQWQKLTQSREKQTTVITPLGMMMLEIQGELELPKD
                     FASLARRDSPNEGRFSEQDGETLIRFGSLQIDGERATLFVGKKQRLLGKVTKLDVPMG
                     IMHFNSKDNKVELVDVMKYKVIFKDRPLPIM"
     gene            <486826..>487662
                     /gene="LNP1"
                     /locus_tag="YHR192W"
                     /db_xref="GeneID:856599"
     mRNA            <486826..>487662
                     /gene="LNP1"
                     /locus_tag="YHR192W"
                     /product="Lnp1p"
                     /transcript_id="NM_001179323.1"
                     /db_xref="GI:296145568"
                     /db_xref="GeneID:856599"
     CDS             486826..487662
                     /gene="LNP1"
                     /locus_tag="YHR192W"
                     /note="Lunapark family member involved in ER network
                     formation; localizes to ER junctions and this localization
                     is regulated by the yeast atlastin ortholog Sey1p;
                     interacts with the reticulon protein Rtn1p; induced in
                     response to the DNA-damaging agent MMS"
                     /codon_start=1
                     /product="Lnp1p"
                     /protein_id="NP_012062.1"
                     /db_xref="GI:6321986"
                     /db_xref="SGD:S000001235"
                     /db_xref="GeneID:856599"
                     /translation="MFSALGKWVRGSRNDKDFVTKYTADLSQITSQIHQLDVALKKSQ
                     SILSQWQSNLTFYGIALTVLALSYTYWEYHGYRPYLVVTALLCIGSLILFKWALTKLY
                     AFYNNNRLRKLAKLRAIHQKKLEKLKEETHYNATSSIIQRFSSGEDQNDDAMVLLDDE
                     LNAKYQELNNLKTELEKFKKESHVKGLKKEDSDAWFDKIISVLAGGNELDSTSSLSPF
                     KKIICPQCHWKSNCYRLASKPIIFICPHCNHKIDEVKEREDAIEAKQPAQPSQSEKEK
                     TK"
     gene            complement(<487712..>488236)
                     /gene="EGD2"
                     /locus_tag="YHR193C"
                     /db_xref="GeneID:856600"
     mRNA            complement(<487712..>488236)
                     /gene="EGD2"
                     /locus_tag="YHR193C"
                     /product="Egd2p"
                     /transcript_id="NM_001179324.3"
                     /db_xref="GI:398364982"
                     /db_xref="GeneID:856600"
     CDS             complement(487712..488236)
                     /gene="EGD2"
                     /locus_tag="YHR193C"
                     /note="Alpha subunit of the nascent polypeptide-associated
                     complex (NAC); involved in protein sorting and
                     translocation; associated with cytoplasmic ribosomes"
                     /codon_start=1
                     /product="Egd2p"
                     /protein_id="NP_012063.3"
                     /db_xref="GI:398364983"
                     /db_xref="SGD:S000001236"
                     /db_xref="GeneID:856600"
                     /translation="MSAIPENANVTVLNKNEKKARELIGKLGLKQIPGIIRVTFRKKD
                     NQIYAIEKPEVFRSAGGNYVVFGEAKVDNFTQKLAAAQQQAQASGIMPSNEDVATKSP
                     EDIQADMQAAAEGSVNAAAEEDDEEGEVDAGDLNKDDIELVVQQTNVSKNQAIKALKA
                     HNGDLVNAIMSLSK"
     gene            <488657..>490396
                     /gene="MDM31"
                     /locus_tag="YHR194W"
                     /db_xref="GeneID:856601"
     mRNA            <488657..>490396
                     /gene="MDM31"
                     /locus_tag="YHR194W"
                     /product="Mdm31p"
                     /transcript_id="NM_001179325.1"
                     /db_xref="GI:296145570"
                     /db_xref="GeneID:856601"
     CDS             488657..490396
                     /gene="MDM31"
                     /locus_tag="YHR194W"
                     /note="Mitochondrial protein that may have a role in
                     phospholipid metabolism; inner membrane protein with
                     similarity to Mdm32p; required for normal mitochondrial
                     morphology and inheritance; interacts genetically with
                     MMM1, MMM2, MDM10, MDM12, and MDM34"
                     /codon_start=1
                     /product="Mdm31p"
                     /protein_id="NP_012064.1"
                     /db_xref="GI:6321988"
                     /db_xref="SGD:S000001237"
                     /db_xref="GeneID:856601"
                     /translation="MSLFTRPFLRSPRQFSVARYVYWARSPALRSNLRIPSIAAASLR
                     AYSNESKTGRDAPPDKKSKKLSNLKYITERDSLLVQTNNIFTKLKINIRWFLKKSTRP
                     FNSDDISAFISWILVSNIFIFIFWTTTFVSLILYLINTVFAQEYLASKIGKFITKNES
                     LSIVFESAIVPDWSSGKISFQKVFVSRRPKVSRGFTKGSQQDALQRAKLALSERILVN
                     QQDFDNGNYTQFDLTIDQVDISLNFRKWINGKGILDEVTINGLRGVIDRTHVVWKKDD
                     DPKNYLNVYQPGDFEISKFTMNDVLCTLYQPNGFRPFQVSIFNCDLPQLRKHWLFYDI
                     LNANNINGTYDNSMFTIHKKFRTDDQHQDPTLLWKQMTRFRVDNLDIDHLNAGIEGPF
                     GWINEGRVNMIGDVLLPDDDAASDSLQLTEILTEIGDRLIKKAKRYTSSLPLVGPGFS
                     PAVDEIDPNDYFIMDFSLRLYNVKAEVPLFTSGLTYINSALIRPIVGYINSHRTYIPI
                     KCRIVKKKSDFEGSWTIYDSYLMRDLSAEAYDAFADYVADDEKRTLRLRRVGFWSLQL
                     ILQVILMSLGAIA"
     gene            <490747..>491712
                     /gene="NVJ1"
                     /locus_tag="YHR195W"
                     /gene_synonym="VAB36"
                     /db_xref="GeneID:856602"
     mRNA            <490747..>491712
                     /gene="NVJ1"
                     /locus_tag="YHR195W"
                     /gene_synonym="VAB36"
                     /product="Nvj1p"
                     /transcript_id="NM_001179326.3"
                     /db_xref="GI:398364994"
                     /db_xref="GeneID:856602"
     CDS             490747..491712
                     /gene="NVJ1"
                     /locus_tag="YHR195W"
                     /gene_synonym="VAB36"
                     /note="Nuclear envelope protein; anchored to the nuclear
                     inner membrane, that interacts with the vacuolar membrane
                     protein Vac8p to promote formation of nucleus-vacuole
                     junctions during piecemeal microautophagy of the nucleus
                     (PMN)"
                     /codon_start=1
                     /product="Nvj1p"
                     /protein_id="NP_012065.3"
                     /db_xref="GI:398364995"
                     /db_xref="SGD:S000001238"
                     /db_xref="GeneID:856602"
                     /translation="MTRPPLVRGIFSLGLSVAVLKGVEKTVRKHLERQGWIEPQKVDY
                     ELIFTIDRLKNLVDNKREALTAEQPDAGELSWRKVFNFISRQSSELDTRIYVLILLLS
                     FLLPIAWTVLDGDRETTLEDKDNDCNVDLIENERRLKHYNDGERAVLQFGKNRSEPII
                     LSYKDMNVLEGEHEFTSKEEHSNSHLTSKSENALNQVGSEDLLGCHLEKQLEEDKNEP
                     NGEADGEDDNNREKDCSSSSEVESQSKCRKESTAEPDSLSRDTRTTSSLKSSTSFPIS
                     FKGSIDLKSLNQPSSLLHIQVSPTKSSNLDAQVNTEQAYSQPFRY"
     gene            <491931..>493658
                     /gene="UTP9"
                     /locus_tag="YHR196W"
                     /db_xref="GeneID:856603"
     mRNA            <491931..>493658
                     /gene="UTP9"
                     /locus_tag="YHR196W"
                     /product="Utp9p"
                     /transcript_id="NM_001179327.1"
                     /db_xref="GI:296145572"
                     /db_xref="GeneID:856603"
     CDS             491931..493658
                     /gene="UTP9"
                     /locus_tag="YHR196W"
                     /note="Nucleolar protein; component of the small subunit
                     (SSU) processome containing the U3 snoRNA that is involved
                     in processing of pre-18S rRNA"
                     /codon_start=1
                     /product="Utp9p"
                     /protein_id="NP_012066.1"
                     /db_xref="GI:6321990"
                     /db_xref="SGD:S000001239"
                     /db_xref="GeneID:856603"
                     /translation="MGSSLDLVASFSHDSTRFAFQASVAQKNNVDIYPLNETKDYVVN
                     SSLVSHIDYETNDMKVSDVIFFGWCSDLIDTQSSNIKRKLDEDEGTGESSEQRCENFF
                     VNGFPDGRIVVYSSNGKDIVNIIKNKKEILGADTDESDIWILDSDKVVKKLQYNNSKP
                     LKTFTLVDGKDDEIVHFQILHQNGTLLVCIITKQMVYIVDPSKRRPSTKYSFEISDAV
                     ACEFSSDGKYLLIANNEELIAYDLKEDSKLIQSWPVQVKTLKTLDDLIMALTTDGKIN
                     NYKIGEADKVCSIVVNEDLEIIDFTPINSKQQVLISWLNVNEPNFESISLKEIETQGY
                     ITINKNEKNNADEADQKKLEEKEEEAQPEVQHEKKETETKINKKVSKSDQVEIANILS
                     SHLEANSTEILDDLMSGSWTEPEIKKFILTKINTVDHLSKIFLTISKSITQNPWNEEN
                     LLPLWLKWLLTLKSGELNSIKDKHTKKNCKHLKSALRSSEEILPVLLGIQGRLEMLRR
                     QAKLREDLAQLSMQEGEDDEIEVIEHSNVISNPLQDQASPVEKLEPDSIVYANGESDE
                     FVDASEYKD"
     gene            <493896..>496187
                     /gene="RIX1"
                     /locus_tag="YHR197W"
                     /gene_synonym="IPI2"
                     /db_xref="GeneID:856604"
     mRNA            <493896..>496187
                     /gene="RIX1"
                     /locus_tag="YHR197W"
                     /gene_synonym="IPI2"
                     /product="Rix1p"
                     /transcript_id="NM_001179328.4"
                     /db_xref="GI:398365004"
                     /db_xref="GeneID:856604"
     CDS             493896..496187
                     /gene="RIX1"
                     /locus_tag="YHR197W"
                     /gene_synonym="IPI2"
                     /note="Component of the Rix1 complex and possibly
                     pre-replicative complexes; required for processing of ITS2
                     sequences from 35S pre-rRNA; component of the pre-60S
                     ribosomal particle with the dynein-related AAA-type ATPase
                     Mdn1p; required for pre-replicative complex (pre-RC)
                     formation and maintenance during DNA replication
                     licensing; relocalizes to the cytosol in response to
                     hypoxia; essential gene"
                     /codon_start=1
                     /product="Rix1p"
                     /protein_id="NP_012067.4"
                     /db_xref="GI:398365005"
                     /db_xref="SGD:S000001240"
                     /db_xref="GeneID:856604"
                     /translation="MSEEFIAVSTLARNLEIAKGNEFHTILATLRSPVYINEQLLKSE
                     LSFLVTKILKLIRSGNDFDLWKGCHTSVVTCAYNPLVLSTHGGQLLAAIYSRLEQKTG
                     FYSSVISSSHGKQLFNTLISSVAIIIDLMKNKPTLSREALVPKLKAIIPTLITLSQYE
                     PELVLPVLQRILKRNTTTFKPFTNKFRTVLINLIISDYASLGTKTQRLVCENFAYLHL
                     LKIQVSDTSDDETQAHHKIYADSNWRTGLMSILSQFKPIIQLCGEILDFEQDNELYKL
                     IKSLPVIDESNNKEEFLPSLKLDFNAPLTLWEIPQRLSLLADMLVAFISLPTPFPIRV
                     PLGGINSLCEVLLGVSNKYLPLKKELRHDNELNGVINTILPQIQFQGIRLWEIMVSKY
                     GKCGLSFFEGILSSIELFIPLKKKSNNEIDFNVVGSLKFEFATVFRLVNMILSHLGHQ
                     LNIISVISQLIEVALFLSHDKTLIDSLFKNRKSIMKQQTKTKQSKRSKSAEGAFSDIY
                     THPELFVCKNSMNWFNEINDFFITALNNWILPSTPHIQILKYSITQSLRLKERFGYIP
                     ESFVNLLRCEVLHPGSERVSILPIAISLLKNINDDMFELLCHPKVPVGMVYQLHKPLD
                     LGEDGEVRDDINKKEVETNESSSNANTGLETLKALENLENVTIPEPKHEVPKVVDDTA
                     IFKKRSVEEVIERESTSSHKKVKFVEETTVDNGEELIVKKAVSQTKEEEKPMEDSEDE
                     EQEEFEIPAIELSDDEEEEEEEE"
     gene            complement(<496315..>497280)
                     /gene="AIM18"
                     /locus_tag="YHR198C"
                     /gene_synonym="FMP22"
                     /db_xref="GeneID:856605"
     mRNA            complement(<496315..>497280)
                     /gene="AIM18"
                     /locus_tag="YHR198C"
                     /gene_synonym="FMP22"
                     /product="Aim18p"
                     /transcript_id="NM_001179329.1"
                     /db_xref="GI:296145574"
                     /db_xref="GeneID:856605"
     CDS             complement(496315..497280)
                     /gene="AIM18"
                     /locus_tag="YHR198C"
                     /gene_synonym="FMP22"
                     /note="hypothetical protein; the authentic, non-tagged
                     protein is detected in highly purified mitochondria in
                     high-throughput studies; null mutant displays elevated
                     frequency of mitochondrial genome loss"
                     /codon_start=1
                     /product="Aim18p"
                     /protein_id="NP_012068.1"
                     /db_xref="GI:6321992"
                     /db_xref="SGD:S000001241"
                     /db_xref="GeneID:856605"
                     /translation="MDRGRCANMLKSLQRTLAKCQKSPSTNHWQCFKRNFTSIRATKY
                     PGRSNSTFHYWPWFAASTLLATSLYYRDRPVQNDDKTDAFPSHTESIQVDSSVSDFPL
                     TITALNFPVSTTFKLLGYGQRHVTFLRFKVYALGLYLAENDENLVSDTLNETYLHKYF
                     LDVDDSKTPKENLARLLKRDDSKSVMMIDDLLDSGMRMLAKITPVRNTDFKHLKEGLV
                     KTISKHPDVANNKDTLAKGLSELNDAFSRKGSVRKNDDLIIELLANGALQFSYHDSKN
                     NEFEVMGVVNNQLVGKFLFSQYLCGEKSPSPQAKKTAIDKLITLL"
     gene            complement(<497490..>498422)
                     /gene="AIM46"
                     /locus_tag="YHR199C"
                     /gene_synonym="FMP34"
                     /db_xref="GeneID:856606"
     mRNA            complement(<497490..>498422)
                     /gene="AIM46"
                     /locus_tag="YHR199C"
                     /gene_synonym="FMP34"
                     /product="Aim46p"
                     /transcript_id="NM_001179330.3"
                     /db_xref="GI:398365014"
                     /db_xref="GeneID:856606"
     CDS             complement(497490..498422)
                     /gene="AIM46"
                     /locus_tag="YHR199C"
                     /gene_synonym="FMP34"
                     /note="hypothetical protein; the authentic, non-tagged
                     protein is detected in highly purified mitochondria in
                     high-throughput studies; null mutant displays elevated
                     frequency of mitochondrial genome loss"
                     /codon_start=1
                     /product="Aim46p"
                     /protein_id="NP_012069.3"
                     /db_xref="GI:398365015"
                     /db_xref="SGD:S000001242"
                     /db_xref="GeneID:856606"
                     /translation="MRLISKVLVKTNCLEVGMRRAPQWYSHYSTTAGNARVNKKGSKV
                     VPVLTGLALASIFAKKWYDDSQIKKADATSVAVDASISAFPKKMGPPQWPFSTQYELI
                     GKGVRCVSSITFKAYGLGIYVAAEDKHLVSEVLDSKFLSQAFIDTAAPPSPENSHQDN
                     LRAALNDPAKAPILINNLLDSGIRLMSKNTPIKAGSFKLLMDGTKKSVLKNPDSQSQD
                     KDRLEAGFQELHDCFRSVKGLVARDDDFFIELNKDCSMNLSYYARKKDEFVILGTVKE
                     PLIGKLLFAHYLAAVDPPSPEARKEVIDALVSLS"
     gene            complement(<498571..>498859)
                     /gene="NBL1"
                     /locus_tag="YHR199C-A"
                     /db_xref="GeneID:2746858"
     mRNA            complement(join(<498571..498719,498787..>498859))
                     /gene="NBL1"
                     /locus_tag="YHR199C-A"
                     /product="Nbl1p"
                     /transcript_id="NM_001184671.1"
                     /db_xref="GI:296145576"
                     /db_xref="GeneID:2746858"
     CDS             complement(join(498571..498719,498787..498859))
                     /gene="NBL1"
                     /locus_tag="YHR199C-A"
                     /note="Subunit of the conserved chromosomal passenger
                     complex (CPC); complex regulates mitotic chromosome
                     segregation; not required for the kinase activity of the
                     complex; mediates the interaction of Sli15p and Bir1p;
                     other complex members are Ipl1p, Sli15p, and Bir1p"
                     /codon_start=1
                     /product="Nbl1p"
                     /protein_id="NP_976247.1"
                     /db_xref="GI:42759857"
                     /db_xref="SGD:S000029704"
                     /db_xref="GeneID:2746858"
                     /translation="MIPALTPEERQKLRSAILHRMQLELETTEKLIENIKEETLKKLN
                     LLQQPDATSAPQSKELIREVLEQEGRRIE"
     gene            <499079..>499885
                     /gene="RPN10"
                     /locus_tag="YHR200W"
                     /gene_synonym="MCB1; SUN1"
                     /db_xref="GeneID:856607"
     mRNA            <499079..>499885
                     /gene="RPN10"
                     /locus_tag="YHR200W"
                     /gene_synonym="MCB1; SUN1"
                     /product="proteasome regulatory particle base subunit
                     RPN10"
                     /transcript_id="NM_001179331.3"
                     /db_xref="GI:398365026"
                     /db_xref="GeneID:856607"
     CDS             499079..499885
                     /gene="RPN10"
                     /locus_tag="YHR200W"
                     /gene_synonym="MCB1; SUN1"
                     /note="Non-ATPase base subunit of the 19S RP of the 26S
                     proteasome; N-terminus plays a role in maintaining the
                     structural integrity of the regulatory particle (RP);
                     binds selectively to polyubiquitin chains; homolog of the
                     mammalian S5a protein"
                     /codon_start=1
                     /product="proteasome regulatory particle base subunit
                     RPN10"
                     /protein_id="NP_012070.3"
                     /db_xref="GI:398365027"
                     /db_xref="SGD:S000001243"
                     /db_xref="GeneID:856607"
                     /translation="MVLEATVLVIDNSEYSRNGDFPRTRFEAQIDSVEFIFQAKRNSN
                     PENTVGLISGAGANPRVLSTFTAEFGKILAGLHDTQIEGKLHMATALQIAQLTLKHRQ
                     NKVQHQRIVAFVCSPISDSRDELIRLAKTLKKNNVAVDIINFGEIEQNTELLDEFIAA
                     VNNPQEETSHLLTVTPGPRLLYENIASSPIILEEGSSGMGAFGGSGGDSDANGTFMDF
                     GVDPSMDPELAMALRLSMEEEQQRQERLRQQQQQQDQPEQSEQPEQHQDK"
     gene            complement(<499950..>501143)
                     /gene="PPX1"
                     /locus_tag="YHR201C"
                     /db_xref="GeneID:856608"
     mRNA            complement(<499950..>501143)
                     /gene="PPX1"
                     /locus_tag="YHR201C"
                     /product="Ppx1p"
                     /transcript_id="NM_001179332.1"
                     /db_xref="GI:296145578"
                     /db_xref="GeneID:856608"
     CDS             complement(499950..501143)
                     /gene="PPX1"
                     /locus_tag="YHR201C"
                     /EC_number="3.6.1.11"
                     /note="Exopolyphosphatase; hydrolyzes inorganic
                     polyphosphate (poly P) into Pi residues; located in the
                     cytosol, plasma membrane, and mitochondrial matrix"
                     /codon_start=1
                     /product="Ppx1p"
                     /protein_id="NP_012071.1"
                     /db_xref="GI:6321995"
                     /db_xref="SGD:S000001244"
                     /db_xref="GeneID:856608"
                     /translation="MSPLRKTVPEFLAHLKSLPISKIASNDVLTICVGNESADMDSIA
                     SAITYSYCQYIYNEGTYSEEKKKGSFIVPIIDIPREDLSLRRDVMYVLEKLKIKEEEL
                     FFIEDLKSLKQNVSQGTELNSYLVDNNDTPKNLKNYIDNVVGIIDHHFDLQKHLDAEP
                     RIVKVSGSCSSLVFNYWYEKLQGDREVVMNIAPLLMGAILIDTSNMRRKVEESDKLAI
                     ERCQAVLSGAVNEVSAQGLEDSSEFYKEIKSRKNDIKGFSVSDILKKDYKQFNFQGKG
                     HKGLEIGLSSIVKRMSWLFNEHGGEADFVNQCRRFQAERGLDVLVLLTSWRKAGDSHR
                     ELVILGDSNVVRELIERVSDKLQLQLFGGNLDGGVAMFKQLNVEATRKQVVPYLEEAY
                     SNLEE"
     rep_origin      501756..501996
                     /note="ARS822;
                     Autonomously Replicating Sequence"
                     /db_xref="SGD:S000118362"
     gene            <502388..>504196
                     /locus_tag="YHR202W"
                     /db_xref="GeneID:856609"
     mRNA            <502388..>504196
                     /locus_tag="YHR202W"
                     /product="hypothetical protein"
                     /transcript_id="NM_001179333.3"
                     /db_xref="GI:398365044"
                     /db_xref="GeneID:856609"
     CDS             502388..504196
                     /locus_tag="YHR202W"
                     /note="hypothetical protein; green fluorescent protein
                     (GFP)-fusion protein localizes to the vacuole, while
                     HA-tagged protein is found in the soluble fraction,
                     suggesting cytoplasmic localization"
                     /codon_start=1
                     /product="hypothetical protein"
                     /protein_id="NP_012072.3"
                     /db_xref="GI:398365045"
                     /db_xref="SGD:S000001245"
                     /db_xref="GeneID:856609"
                     /translation="MILKLVHCLVALTGLIFAKPYQQQQAVLAPSQDVPLRDIHIGDI
                     NFIHTTDTHGWLGSHLSQNDYDADWGDFVAFVDILREKILRQSRDVIVIDTGDKRDGN
                     GLSDATWPPGLRSSEIFNMMDYDLLTLGNHELYTAESAILEYRGTSQSSKFKDKYVCS
                     NVEFIEDDGTRVPFGNKYITFETPIMKQRVLALSFLFSFQRANNRAIVTPPLEEITQK
                     SWFQNMVETNREEEIDLIIVFGHLPATDPTEREMHKIHALIRKYYPNTVIQYFGGHTH
                     IRDFVQLDSKSTCLQSGRFAETVGFLSINMTDPVDAESPIFSRRYIDFNKEAFKYHLS
                     KLGHDSNVPVSTKKGKTISRLVNDLRHELNLNEKLGYIPQTYYVSTRPLNSEENLYHL
                     ITHKILPNLIPPKNYEPSMSRFILINTGSVRYDLYKGPFTKDTEYIVMPFNNDWRFIT
                     VPLVVASRVETYLNKGPVIASLGIPSSSHHKQHFGGFQKCPFINNPNLSEGYTTEDDF
                     GCHGDDTPHNSQREYDIPNVVQCKEVKKVQEEEADPSKMVHVIFYSFMELDILNAVNS
                     IINDLGLRMENLTTNDCSHYGGDSTKKLLRDYFSQF"
     gene            complement(<504476..>505530)
                     /gene="RPS4B"
                     /locus_tag="YHR203C"
                     /db_xref="GeneID:856610"
     mRNA            complement(join(<504476..505247,505517..>505530))
                     /gene="RPS4B"
                     /locus_tag="YHR203C"
                     /product="ribosomal 40S subunit protein S4B"
                     /transcript_id="NM_001179334.1"
                     /db_xref="GI:296145580"
                     /db_xref="GeneID:856610"
     CDS             complement(join(504476..505247,505517..505530))
                     /gene="RPS4B"
                     /locus_tag="YHR203C"
                     /note="Protein component of the small (40S) ribosomal
                     subunit; homologous to mammalian ribosomal protein S4, no
                     bacterial homolog; RPS4B has a paralog, RPS4A, that arose
                     from the whole genome duplication"
                     /codon_start=1
                     /product="ribosomal 40S subunit protein S4B"
                     /protein_id="NP_012073.1"
                     /db_xref="GI:6321997"
                     /db_xref="SGD:S000001246"
                     /db_xref="GeneID:856610"
                     /translation="MARGPKKHLKRLAAPHHWLLDKLSGCYAPRPSAGPHKLRESLPL
                     IVFLRNRLKYALNGREVKAILMQRHVKVDGKVRTDTTYPAGFMDVITLDATNENFRLV
                     YDVKGRFAVHRITDEEASYKLGKVKKVQLGKKGVPYVVTHDGRTIRYPDPNIKVNDTV
                     KIDLASGKITDFIKFDAGKLVYVTGGRNLGRIGTIVHKERHDGGFDLVHIKDSLDNTF
                     VTRLNNVFVIGEQGKPYISLPKGKGIKLSIAEERDRRRAQQGL"
     gene            <506319..>508709
                     /gene="MNL1"
                     /locus_tag="YHR204W"
                     /gene_synonym="HTM1"
                     /db_xref="GeneID:856611"
     mRNA            <506319..>508709
                     /gene="MNL1"
                     /locus_tag="YHR204W"
                     /gene_synonym="HTM1"
                     /product="alpha-1,2-mannosidase MNL1"
                     /transcript_id="NM_001179335.3"
                     /db_xref="GI:398365054"
                     /db_xref="GeneID:856611"
     CDS             506319..508709
                     /gene="MNL1"
                     /locus_tag="YHR204W"
                     /gene_synonym="HTM1"
                     /EC_number="3.2.1.24"
                     /note="Alpha-1,2-specific exomannosidase of the
                     endoplasmic reticulum; in complex with Pdi1p, generates a
                     Man7GlcNac2 oligosaccharide signal on glycoproteins
                     destined for ubiquitin-proteasome degradation"
                     /codon_start=1
                     /product="alpha-1,2-mannosidase MNL1"
                     /protein_id="NP_012074.3"
                     /db_xref="GI:398365055"
                     /db_xref="SGD:S000001247"
                     /db_xref="GeneID:856611"
                     /translation="MVCCLWVLLALLLHLDHVACEDDAYSFTSKELKAYKQEVKELFY
                     FGFDNYLEHGYPYDEVKPISCVPKKRNFEDPTDQGTNDILGNFTITLIDSLTTIAILE
                     DRPQFLKAVRLVERTFPDGNFDIDSTIQVFEITIRVIGSLLSSHLYATDPTKAVYLGD
                     DYDGSLLRLAQNMADRLLPAYLTSTGLPMPRRNIKRKWDVSEFPEFLETENNVAAMAS
                     PMFEFTILSYLTGDPKYEKVTRYAFDKTWSLRTGLDLLPMSFHPEKLTPYTPMTGIGA
                     SIDSLFEYALKGAILFDDSELMEVWNVAYEALKTNCKNDWFFANVMADTGHLFVPWID
                     SLSAFFSGLQVLAGDLDDAIANHLMFLKMWNTFGGIPERWNFSPPEFPPLSPLERSGA
                     VALDNILPLEWYPLRPEFFESTYFLYRATKDPFYLNIGVHLLKDLKQRFKSNCGFAGF
                     QNVITGELQDRMETFVLSETLKYLYLLFDEENELHNSASDVIFSTEAHPMWLPQEVRS
                     NYKRNAKFNNSVYSSHLEICQKKDREQAGENTLSQRIVGFAKSIFHKGPPDEEATDPI
                     IDYTIDTELPGTCSIKPHHVIGDEFWYSPMLSNFDRLFEIDSRFAATLIKPSHMHNYN
                     AIELEPGFYNRWSNPQFSTCLIPPTTEIFELLFDLPGYHQLNPLMLENKTITFETFGG
                     RSRLKIEKLQIYQIDYYGDLITASTFQDVSRKDIFSNACDAVASLYSPTYLYRVVAIN
                     GRILPRHGSVQIKKHSPVLTSNGTREEDEFKMDGIGINDHSQLMLECTPIINLFIV"
     gene            <509363..>511837
                     /gene="SCH9"
                     /locus_tag="YHR205W"
                     /gene_synonym="HRM2; KOM1"
                     /db_xref="GeneID:856612"
     mRNA            <509363..>511837
                     /gene="SCH9"
                     /locus_tag="YHR205W"
                     /gene_synonym="HRM2; KOM1"
                     /product="serine/threonine protein kinase SCH9"
                     /transcript_id="NM_001179336.1"
                     /db_xref="GI:296145582"
                     /db_xref="GeneID:856612"
     CDS             509363..511837
                     /gene="SCH9"
                     /locus_tag="YHR205W"
                     /gene_synonym="HRM2; KOM1"
                     /EC_number="2.7.11.1"
                     /note="AGC family protein kinase; functional ortholog of
                     mammalian S6 kinase; phosphorylated by Tor1p and required
                     for TORC1-mediated regulation of ribosome biogenesis,
                     translation initiation, and entry into G0 phase; involved
                     in transactivation of osmostress-responsive genes;
                     regulates G1 progression, cAPK activity and nitrogen
                     activation of the FGM pathway; integrates nutrient signals
                     and stress signals from sphingolipids to regulate
                     lifespan"
                     /codon_start=1
                     /product="serine/threonine protein kinase SCH9"
                     /protein_id="NP_012075.1"
                     /db_xref="GI:6321999"
                     /db_xref="SGD:S000001248"
                     /db_xref="GeneID:856612"
                     /translation="MMNFFTSKSSNQDTGFSSQHQHPNGQNNGNNNSSTAGNDNGYPC
                     KLVSSGPCASSNNGALFTNFTLQTATPTTAISQDLYAMGTTGITSENALFQMKSMNNG
                     ISSVNNNNSNTPTIITTSQEETNAGNVHGDTGGNSLQNSEDDNFSSSSTTKCLLSSTS
                     SLSINQREAAAAAYGPDTDIPRGKLEVTIIEARDLVTRSKDSQPYVVCTFESSEFISN
                     GPESLGAINNNNNNNNNNQHNQNQHINNNNENTNPDAASQHHNNNSGWNGSQLPSIKE
                     HLKKKPLYTHRSSSQLDQLNSCSSVTDPSKRSSNSSSGSSNGPKNDSSHPIWHHKTTF
                     DVLGSHSELDISVYDAAHDHMFLGQVRLYPMIHNLAHASQHQWHSLKPRVIDEVVSGD
                     ILIKWTYKQTKKRHYGPQDFEVLRLLGKGTFGQVYQVKKKDTQRIYAMKVLSKKVIVK
                     KNEIAHTIGERNILVTTASKSSPFIVGLKFSFQTPTDLYLVTDYMSGGELFWHLQKEG
                     RFSEDRAKFYIAELVLALEHLHDNDIVYRDLKPENILLDANGNIALCDFGLSKADLKD
                     RTNTFCGTTEYLAPELLLDETGYTKMVDFWSLGVLIFEMCCGWSPFFAENNQKMYQKI
                     AFGKVKFPRDVLSQEGRSFVKGLLNRNPKHRLGAIDDGRELRAHPFFADIDWEALKQK
                     KIPPPFKPHLVSETDTSNFDPEFTTASTSYMNKHQPMMTATPLSPAMQAKFAGFTFVD
                     ESAIDEHVNNNRKFLQNSYFMEPGSFIPGNPNLPPDEDVIDDDGDEDINDGFNQEKNM
                     NNSHSQMDFDGDQHMDDEFVSGRFEI"
     gene            <512732..>514600
                     /gene="SKN7"
                     /locus_tag="YHR206W"
                     /gene_synonym="BRY1; POS9"
                     /db_xref="GeneID:856613"
     mRNA            <512732..>514600
                     /gene="SKN7"
                     /locus_tag="YHR206W"
                     /gene_synonym="BRY1; POS9"
                     /product="kinase-regulated stress-responsive transcription
                     factor SKN7"
                     /transcript_id="NM_001179337.3"
                     /db_xref="GI:398365082"
                     /db_xref="GeneID:856613"
     CDS             512732..514600
                     /gene="SKN7"
                     /locus_tag="YHR206W"
                     /gene_synonym="BRY1; POS9"
                     /note="Nuclear response regulator and transcription
                     factor; physically interacts with the Tup1-Cyc8 complex
                     and recruits Tup1p to its targets; part of a branched
                     two-component signaling system; required for optimal
                     induction of heat-shock genes in response to oxidative
                     stress; involved in osmoregulation; relocalizes to the
                     cytosol in response to hypoxia; SKN7 has a paralog, HMS2,
                     that arose from the whole genome duplication"
                     /codon_start=1
                     /product="kinase-regulated stress-responsive transcription
                     factor SKN7"
                     /protein_id="NP_012076.3"
                     /db_xref="GI:398365083"
                     /db_xref="SGD:S000001249"
                     /db_xref="GeneID:856613"
                     /translation="MSFSTINSNVNKTTGDSNNNTTENSSTADLLGMDLLQSGPRLMN
                     TMQPNNSSDMLHINNKTNNVQQPAGNTNISSANAGAKAPANEFVRKLFRILENNEYPD
                     IVTWTENGKSFVVLDTGKFTTHILPNHFKHSNFASFVRQLNKYDFHKVKRSPEERQRC
                     KYGEQSWEFQHPEFRVHYGKGLDNIKRKIPAQRKVLLDESQKALLHFNSEGTNPNNPS
                     GSLLNESTTELLLSNTVSKDAFGNLRRRVDKLQKELDMSKMESYATKVELQKLNSKYN
                     TVIESLITFKTINENLLNNFNTLCSTLANNGIEVPIFGDNGNRNPTGNTNPATTTAIQ
                     SNNNTNNASPATSTVSLQLPNLPDQNSLTPNAQNNTVTLRKGFHVLLVEDDAVSIQLC
                     SKFLRKYGCTVQVVSDGLSAISTLEKYRYDLVLMDIVMPNLDGATATSIVRSFDNETP
                     IIAMTGNIMNQDLITYLQHGMNDILAKPFTRDDLHSILIRYLKDRIPLCEQQLPPRNS
                     SPQTHSNTNTANSNPNTINEQSLAMLPQDNPSTTTPVTPGASISSAQHVQQGQQEQQH
                     QIFHAQQQQQHHNAIANARSDVAIPNLEHEINTVPHSSMGSTPQLPQSTLQENQLS"
     gene            complement(<514905..>516485)
                     /gene="SET5"
                     /locus_tag="YHR207C"
                     /db_xref="GeneID:856614"
     mRNA            complement(<514905..>516485)
                     /gene="SET5"
                     /locus_tag="YHR207C"
                     /product="Set5p"
                     /transcript_id="NM_001179338.1"
                     /db_xref="GI:296145584"
                     /db_xref="GeneID:856614"
     CDS             complement(514905..516485)
                     /gene="SET5"
                     /locus_tag="YHR207C"
                     /EC_number="2.1.1.-"
                     /note="Methyltransferase involved in methylation of
                     histone H4 Lys5, -8, -12; S-adenosylmethionine-dependent;
                     zinc-finger protein, contains one canonical and two
                     unusual fingers in unusual arrangements; deletion enhances
                     replication of positive-strand RNA virus"
                     /codon_start=1
                     /product="Set5p"
                     /protein_id="NP_012077.1"
                     /db_xref="GI:6322001"
                     /db_xref="SGD:S000001250"
                     /db_xref="GeneID:856614"
                     /translation="MTLTIKIGTLNDSDQSAVHNGTENGSDFRKITPTEEEICDDVVL
                     LWKEEPGTEDATIQHLYDRITERNQSWKLSASRFRKILNEHHLYDTDLETVSLYKDKI
                     HFPKALDSDAKVEVKFIDDEHGRGLFAKRDFSKGQIILKENKPIVYIPPLDKLFLISN
                     GKACARCGKALYDLTQHKIMVHYLDCEVCKAIWCSEKCKKAHASLHELLYHSWRSNRI
                     DILHAGNWKRFVNYCEKYCFTAAFSVGLIYGSMLLDTTGEVKEQWQKLASISQRERIK
                     LRDASGIGSTFSLLNGTTVHTEEESDNGTKKGVEKNIDDETVWEKCYELFCGAFPKAS
                     EEIDFEKFLTMIGTFNINQYNGQVYHWISFINHDCEPNAYIEQVEEHEELRLHARKPI
                     KKGEQIRITYVNPLHGVRLRRRELRVNWGFLCQCDRCQNELSTFERVPNLEKKNADAN
                     LGVEKIDSNDSSEDGSKKSTGNRKSSMREAQPDLKEILKNGKEFELDIPETVDTQGNV
                     RKTSVRFDSNVSVAVDER"
     gene            <517532..>518713
                     /gene="BAT1"
                     /locus_tag="YHR208W"
                     /gene_synonym="ECA39; TWT1"
                     /db_xref="GeneID:856615"
     mRNA            <517532..>518713
                     /gene="BAT1"
                     /locus_tag="YHR208W"
                     /gene_synonym="ECA39; TWT1"
                     /product="branched-chain-amino-acid transaminase BAT1"
                     /transcript_id="NM_001179339.3"
                     /db_xref="GI:398365102"
                     /db_xref="GeneID:856615"
     CDS             517532..518713
                     /gene="BAT1"
                     /locus_tag="YHR208W"
                     /gene_synonym="ECA39; TWT1"
                     /EC_number="2.6.1.42"
                     /note="Mitochondrial branched-chain amino acid (BCAA)
                     aminotransferase; preferentially involved in BCAA
                     biosynthesis; homolog of murine ECA39; highly expressed
                     during logarithmic phase and repressed during stationary
                     phase; BAT1 has a paralog, BAT2, that arose from the whole
                     genome duplication"
                     /codon_start=1
                     /product="branched-chain-amino-acid transaminase BAT1"
                     /protein_id="NP_012078.3"
                     /db_xref="GI:398365103"
                     /db_xref="SGD:S000001251"
                     /db_xref="GeneID:856615"
                     /translation="MLQRHSLKLGKFSIRTLATGAPLDASKLKITRNPNPSKPRPNEE
                     LVFGQTFTDHMLTIPWSAKEGWGTPHIKPYGNLSLDPSACVFHYAFELFEGLKAYRTP
                     QNTITMFRPDKNMARMNKSAARICLPTFESEELIKLTGKLIEQDKHLVPQGNGYSLYI
                     RPTMIGTSKGLGVGTPSEALLYVITSPVGPYYKTGFKAVRLEATDYATRAWPGGVGDK
                     KLGANYAPCILPQLQAAKRGYQQNLWLFGPEKNITEVGTMNVFFVFLNKVTGKKELVT
                     APLDGTILEGVTRDSVLTLARDKLDPQEWDINERYYTITEVATRAKQGELLEAFGSGT
                     AAVVSPIKEIGWNNEDIHVPLLPGEQCGALTKQVAQWIADIQYGRVNYGNWSKTVADL
                     N"
     gene            <519437..>520312
                     /gene="CRG1"
                     /locus_tag="YHR209W"
                     /db_xref="GeneID:856616"
     mRNA            <519437..>520312
                     /gene="CRG1"
                     /locus_tag="YHR209W"
                     /product="Crg1p"
                     /transcript_id="NM_001179340.1"
                     /db_xref="GI:296145586"
                     /db_xref="GeneID:856616"
     CDS             519437..520312
                     /gene="CRG1"
                     /locus_tag="YHR209W"
                     /EC_number="2.1.1.-"
                     /note="S-AdoMet-dependent methyltransferase involved in
                     lipid homeostasis; mediates resistance to a drug
                     cantharidin"
                     /codon_start=1
                     /product="Crg1p"
                     /protein_id="NP_012079.1"
                     /db_xref="GI:6322003"
                     /db_xref="SGD:S000001252"
                     /db_xref="GeneID:856616"
                     /translation="MPKTSYLNKNFESAHYNNVRPSYPLSLVNEIMKFHKGTRKSLVD
                     IGCGTGKATFVVEPYFKEVIGIDPSSAMLSIAEKETNERRLDKKIRFINAPGEDLSSI
                     RPESVDMVISAEAIHWCNLERLFQQVSSILRSDGTFAFWFYIQPEFVDFPEALNVYYK
                     YGWSKDYMGKYLNDNQREILLNYGGEKLRSLLSDRFGDIEVTIYSPSDPNASTVTAEN
                     SQFLWRAAITLNQFKEFVKSWSIYTSWARDNPSKPDIADIFINELKEICHCEDLNVPL
                     KIEWSTFYYLCRKRE"
     gene            complement(<520712..>521737)
                     /locus_tag="YHR210C"
                     /db_xref="GeneID:856617"
     mRNA            complement(<520712..>521737)
                     /locus_tag="YHR210C"
                     /product="aldose 1-epimerase superfamily protein"
                     /transcript_id="NM_001179341.3"
                     /db_xref="GI:398365118"
                     /db_xref="GeneID:856617"
     CDS             complement(520712..521737)
                     /locus_tag="YHR210C"
                     /EC_number="5.-.-.-"
                     /note="Putative aldose 1-epimerase superfamily protein;
                     non-essential gene; highly expressed under anaeorbic
                     conditions"
                     /codon_start=1
                     /product="aldose 1-epimerase superfamily protein"
                     /protein_id="NP_012080.3"
                     /db_xref="GI:398365119"
                     /db_xref="SGD:S000001253"
                     /db_xref="GeneID:856617"
                     /translation="MSNNKAGGEYEVITIGDAKKLQATISELGATLLDLKVNNESIVL
                     GYPDIHGYISDGYNYIGATVGRYANRIYKGMFSMEDGPHQLTVNNCGNTNHSSISSFH
                     LKKYKASKVQNPLDDLYIVEFTLLDDRTLPNEFPGDLAVNLKYTLNVADMTLDLEYEA
                     KLVSGEATPINMTNHTYFNLNKTMDKKSISGTEVRLCSDKSLEVSEGALIPTGKIVQR
                     KIATFDSSKPTILQDDGPIYDYAFIVDENKNLKTTDSVSVNKLVPAFKAYHPASRLSL
                     EVSTTEPTVLFYTGDNLCDGFTPRSGFAVEQGRYVDAINRDGWRDCVLLRRGEVYTSK
                     TRYRFAV"
     gene            <525392..>528619
                     /gene="FLO5"
                     /locus_tag="YHR211W"
                     /db_xref="GeneID:856618"
     mRNA            <525392..>528619
                     /gene="FLO5"
                     /locus_tag="YHR211W"
                     /product="flocculin FLO5"
                     /transcript_id="NM_001179342.1"
                     /db_xref="GI:296145588"
                     /db_xref="GeneID:856618"
     CDS             525392..528619
                     /gene="FLO5"
                     /locus_tag="YHR211W"
                     /note="Lectin-like cell wall protein (flocculin) involved
                     in flocculation; binds mannose chains on the surface of
                     other cells, confers floc-forming ability that is
                     chymotrypsin resistant but heat labile; FLO5 has a
                     paralog, FLO1, that arose from a segmental duplication"
                     /codon_start=1
                     /product="flocculin FLO5"
                     /protein_id="NP_012081.1"
                     /db_xref="GI:6322005"
                     /db_xref="SGD:S000001254"
                     /db_xref="GeneID:856618"
                     /translation="MTIAHHCIFLVILAFLALINVASGATEACLPAGQRKSGMNINFY
                     QYSLKDSSTYSNAAYMAYGYASKTKLGSVGGQTDISIDYNIPCVSSSGTFPCPQEDSY
                     GNWGCKGMGACSNSQGIAYWSTDLFGFYTTPTNVTLEMTGYFLPPQTGSYTFSFATVD
                     DSAILSVGGSIAFECCAQEQPPITSTNFTINGIKPWDGSLPDNITGTVYMYAGYYYPL
                     KVVYSNAVSWGTLPISVELPDGTTVSDNFEGYVYSFDDDLSQSNCTIPDPSIHTTSTI
                     TTTTEPWTGTFTSTSTEMTTITDTNGQLTDETVIVIRTPTTASTITTTTEPWTGTFTS
                     TSTEMTTVTGTNGQPTDETVIVIRTPTSEGLITTTTEPWTGTFTSTSTEMTTVTGTNG
                     QPTDETVIVIRTPTSEGLITTTTEPWTGTFTSTSTEVTTITGTNGQPTDETVIVIRTP
                     TSEGLITTTTEPWTGTFTSTSTEMTTVTGTNGQPTDETVIVIRTPTSEGLISTTTEPW
                     TGTFTSTSTEVTTITGTNGQPTDETVIVIRTPTSEGLITTTTEPWTGTFTSTSTEMTT
                     VTGTNGQPTDETVIVIRTPTSEGLITRTTEPWTGTFTSTSTEVTTITGTNGQPTDETV
                     IVIRTPTTAISSSLSSSSGQITSSITSSRPIITPFYPSNGTSVISSSVISSSVTSSLV
                     TSSSFISSSVISSSTTTSTSIFSESSTSSVIPTSSSTSGSSESKTSSASSSSSSSSIS
                     SESPKSPTNSSSSLPPVTSATTGQETASSLPPATTTKTSEQTTLVTVTSCESHVCTES
                     ISSAIVSTATVTVSGVTTEYTTWCPISTTETTKQTKGTTEQTKGTTEQTTETTKQTTV
                     VTISSCESDICSKTASPAIVSTSTATINGVTTEYTTWCPISTTESKQQTTLVTVTSCE
                     SGVCSETTSPAIVSTATATVNDVVTVYPTWRPQTTNEQSVSSKMNSATSETTTNTGAA
                     ETKTAVTSSLSRFNHAETQTASATDVIGHSSSVVSVSETGNTMSLTSSGLSTMSQQPR
                     STPASSMVGSSTASLEISTYAGSANSLLAGSGLSVFIASLLLAII"
     LTR             complement(530049..530379)
                     /note="Ty1 LTR"
                     /db_xref="SGD:S000007000"
     gene            <538742..>538945
                     /locus_tag="YHR212W-A"
                     /db_xref="GeneID:1466531"
     mRNA            <538742..>538945
                     /locus_tag="YHR212W-A"
                     /product="hypothetical protein"
                     /transcript_id="NM_001184598.3"
                     /db_xref="GI:398365142"
                     /db_xref="GeneID:1466531"
     CDS             538742..538945
                     /locus_tag="YHR212W-A"
                     /note="Pseudogenic fragment with similarity to flocculins;
                     identified by gene-trapping, microarray-based expression
                     analysis, and genome-wide homology searching; YHR212W-A
                     has a paralog, YAR061W, that arose from a segmental
                     duplication"
                     /codon_start=1
                     /product="hypothetical protein"
                     /protein_id="NP_878091.3"
                     /db_xref="GI:398365143"
                     /db_xref="SGD:S000028650"
                     /db_xref="GeneID:1466531"
                     /translation="MPYHYLFLALFTYLATSNVVSGSTQACLPVGPRKNGMNVNFYKY
                     SLLDSTTYSYPQYMTSGYASNWN"
     gene            <539151..>539747
                     /locus_tag="YHR213W"
                     /db_xref="GeneID:856620"
     mRNA            <539151..>539747
                     /locus_tag="YHR213W"
                     /product="hypothetical protein"
                     /transcript_id="NM_001179344.1"
                     /db_xref="GI:296145590"
                     /db_xref="GeneID:856620"
     CDS             539151..539747
                     /locus_tag="YHR213W"
                     /note="Pseudogenic fragment with similarity to flocculins;
                     YHR213W has a paralog, YAR062W, that arose from a
                     segmental duplication"
                     /codon_start=1
                     /product="hypothetical protein"
                     /protein_id="NP_012083.1"
                     /db_xref="GI:6322007"
                     /db_xref="SGD:S000001256"
                     /db_xref="GeneID:856620"
                     /translation="MTGYFLPPQTSSYTFRFAKVDDSAILSVGGNVAFECCAQEQPPI
                     TSTDFTINGIKPWQGSLPDNIGGTVYMYAGYYYPLKVVYSNAVSWGTLPISVELPDGT
                     TVSDDFEGYVYSFDDDLSQSNCTIPDPSKHTTSIVTTTTELWTGTFTSTSTEMTTVTG
                     TNGQPTDETVIVAKAPTTATSSSLSSSSSEQITSSITS"
     gene            <540549..>540782
                     /locus_tag="YHR213W-A"
                     /db_xref="GeneID:1466532"
     mRNA            <540549..>540782
                     /locus_tag="YHR213W-A"
                     /product="hypothetical protein"
                     /transcript_id="NM_001184599.3"
                     /db_xref="GI:398365160"
                     /db_xref="GeneID:1466532"
     CDS             540549..540782
                     /locus_tag="YHR213W-A"
                     /note="hypothetical protein; identified by gene-trapping,
                     microarray-based expression analysis, and genome-wide
                     homology searching"
                     /codon_start=1
                     /product="hypothetical protein"
                     /protein_id="NP_878092.3"
                     /db_xref="GI:398365161"
                     /db_xref="SGD:S000028651"
                     /db_xref="GeneID:1466532"
                     /translation="MLAKTGDVVVQKVPVIRLSVFLHFFFVFPFCLLHRLYMGMKQVQ
                     EFIMEPKGSVFVVRATLRVSLENAGKIFFNETE"
     gene            <540800..>541099
                     /locus_tag="YHR213W-B"
                     /db_xref="GeneID:1466533"
     mRNA            <540800..>541099
                     /locus_tag="YHR213W-B"
                     /product="hypothetical protein"
                     /transcript_id="NM_001184600.1"
                     /db_xref="GI:296145592"
                     /db_xref="GeneID:1466533"
     CDS             540800..541099
                     /locus_tag="YHR213W-B"
                     /note="Pseudogenic fragment with similarity to flocculins;
                     identified by gene-trapping, microarray-based expression
                     analysis, and genome-wide homology searching; YHR213W-B
                     has a paralog, YAR064W, that arose from a segmental
                     duplication"
                     /codon_start=1
                     /product="hypothetical protein"
                     /protein_id="NP_878093.1"
                     /db_xref="GI:33438811"
                     /db_xref="SGD:S000028652"
                     /db_xref="GeneID:1466533"
                     /translation="MLIDFCCSYIAGTHGRERAPSFTGTFVSHVSAENNCRPRRSEIT
                     QPCASGTEKKHFAATEKQCTNSLEGSRKDFLSLPLGHSYLFLFCFWRMICSEPKL"
     gene            <541651..>542262
                     /locus_tag="YHR214W"
                     /db_xref="GeneID:856621"
     mRNA            <541651..>542262
                     /locus_tag="YHR214W"
                     /product="hypothetical protein"
                     /transcript_id="NM_001179345.3"
                     /db_xref="GI:398365168"
                     /db_xref="GeneID:856621"
     CDS             541651..542262
                     /locus_tag="YHR214W"
                     /note="hypothetical protein; predicted to be a
                     glycosylphosphatidylinositol-modified (GPI) protein;
                     YHR214W has a paralog, YAR066W, that arose from a
                     segmental duplication"
                     /codon_start=1
                     /product="hypothetical protein"
                     /protein_id="NP_012084.3"
                     /db_xref="GI:398365169"
                     /db_xref="SGD:S000001257"
                     /db_xref="GeneID:856621"
                     /translation="MFNRFNKFQAAVALALLSRGALGDSYTNSTSSADLSSITSVSSA
                     SASATASDSLSSSDGTVYLPSTTISGDLTVTGKVIATEAVEVAAGGKLTLLDGEKYVF
                     SSDLKVHGDLVVEKSEASYEGTAFDVSGETFEVSGNFSAEETGAVSASIYSFTPSSFK
                     SSGDISLSLSKAKKGEVTFSPYSNAGTFSLSNAILNGGSVSGL"
     mobile_element  complement(543610..549637)
                     /note="YHRCTy1-1; Ty1 element, LTR retrotransposon of the
                     Copia (Pseudoviridae) group; contains co-transcribed genes
                     TYA Gag and TYB Pol, encoding proteins involved in
                     structure and function of virus-like particles, flanked by
                     two direct repeats"
                     /mobile_element_type="retrotransposon:YHRCTy1-1"
                     /db_xref="SGD:S000007006"
     LTR             complement(543610..543941)
                     /note="Ty1 LTR"
                     /db_xref="SGD:S000007001"
     gene            complement(<543964..>549346)
                     /locus_tag="YHR214C-B"
                     /db_xref="GeneID:856623"
     mRNA            complement(<543964..>549346)
                     /locus_tag="YHR214C-B"
                     /product="gag-pol fusion protein"
                     /transcript_id="NM_001181431.2"
                     /db_xref="GI:757874315"
                     /db_xref="GeneID:856623"
     CDS             complement(join(543964..547929,547931..549346))
                     /locus_tag="YHR214C-B"
                     /EC_number="3.4.23.-"
                     /EC_number="3.1.26.4"
                     /EC_number="2.7.7.7"
                     /EC_number="2.7.7.49"
                     /ribosomal_slippage
                     /note="Retrotransposon TYA Gag and TYB Pol genes;
                     transcribed/translated as one unit; polyprotein is
                     processed to make a nucleocapsid-like protein (Gag),
                     reverse transcriptase (RT), protease (PR), and integrase
                     (IN); similar to retroviral genes; YHR214C-B has a
                     paralog, YAR070C, that arose from a segmental duplication"
                     /codon_start=1
                     /product="gag-pol fusion protein"
                     /protein_id="NP_012086.1"
                     /db_xref="GI:6322010"
                     /db_xref="SGD:S000003534"
                     /db_xref="GeneID:856623"
                     /translation="MESQQLSNYPHISHGSACASVTSKEVHTNQDPLDVSASKIQEYD
                     KASTKANSQQTTTPASSAVPENLHHASPQPASVPPPQNGPYPQQCMMTQNQANPSGWS
                     FYGHPSMIPYTPYQMSPMYFPPGPQSQFPQYPSSVGTPLSTPSPESGNTFTDSSSADS
                     DMTSTKKYVRPPPMLTSPNDFPNWVKTYIKFLQNSNLGGIIPTVNGKPVPPMLTSPND
                     FPNWVKTYIKFLQNSNLGGIIPTVNGKPVRQITDDELTFLYNTFQIFAPSQFLPTWVK
                     DILSVDYTDIMKILSKSIEKMQSDTQEANDIVTLANLQYNGSTPADAFETKVTNIIDR
                     LNNNGIHINNKVACQLIMRGLSGEYKFLRYTRHRHLNMTVAELFLDIHAIYEEQQGSR
                     NSKPNYRRNPSDEKNDSRSYTNTTKPKVIARNPQKTNNSKSKTARAHNVSTSNNSPST
                     DNDSISKSTTEPIQLNNKHDLHLGQKLTESTVNHTNHSDDELPGHLLLDSGASRTLIR
                     SAHHIHSASSNPDINVVDAQKRNIPINAIGDLQFHFQDNTKTSIKVLHTPNIAYDLLS
                     LNELAAVDITACFTKNVLERSDGTVLAPIVKYGDFYWVSKKYLLPSNISVPTINNVHT
                     SESTRKYPYPFIHRMLAHANAQTIRYSLKNNTITYFNESDVDWSSAIDYQCPDCLIGK
                     STKHRHIKGSRLKYQNSYEPFQYLHTDIFGPVHNLPKSAPSYFISFTDETTKFRWVYP
                     LHDRREDSILDVFTTILAFIKNQFQASVLVIQMDRGSEYTNRTLHKFLEKNGITPCYT
                     TTADSRAHGVAERLNRTLLDDCRTQLQCSGLPNHLWFSAIEFSTIVRNSLASPKSKKS
                     ARQHAGLAGLDISTLLPFGQPVIVNDHNPNSKIHPRGIPGYALHPSRNSYGYIIYLPS
                     LKKTVDTTNYVILQGKESRLDQFNYDALTFDEDLNRLTASYHSFIASNEIQQSNDLNI
                     ESDHDFQSDIELHPEQLRNVLSKAVSPTDSTPPSTHTEDSKRVSKTNIRAPREVDPNI
                     SESNILPSKKRSSTPQISDIESTGSGGMHRLDVPLLAPMSQSNTHESSHASKSKDFRH
                     SDSYSDNETNHTNVPISSTGGTNNKTVPQTSEQETEKRIIHRSPSIDTSSSESNSLHH
                     VVPIKTSDTCPKENTEESIIADLPLPDLPPEPPTELSDSFKELPPINSHQTNSSLGGI
                     GDSNAYTTINSKKRSLEDNETEIKVSRDTWNTKNMRSLEPPRSKKRIHLIAAVKAVKS
                     IKPIRTTLRYDEAITYNKDIKEKEKYIQAYHKEVNQLLMMKTWDTDRYYDRKEIDPKR
                     VINSMFIFNRKRDGTHKARFVARGDIQHPDTYDPGMQSNTVHHYALMTSLSLALDNNY
                     YITQLDISSAYLYADIKEELYIRPPPHLGMNDKLIRLKKSLYGLKQSGANWYETIKSY
                     LIKQCGMEEVRGWSCVFKNSQVTICLFVDDMILFSKDLNANKKIITTLKKQYDTKIIN
                     LGESDNEIQYDILGLEIKYQRGKYMKLGMENSLTEKIPKLNVPLNPKGRKLSAPGQPG
                     LYIDQDELEIDEDEYKEKVHEMQKLIGLASYVGYKFRFDLLYYINTLAQHILFPSRQV
                     LDMTYELIQFMWDTRDKQLIWHKNKPTEPDNKLVAISDASYGNQPYYKSQIGNIYLLN
                     GKVIGGKSTKASLTCTSTTEAEIHAISESVPLLNNLSHLVQELNKKPITKGLLTDSKS
                     TISIIISNNEEKFRNRFFGTKAMRLRDEVSGNHLHVCYIETKKNIADVMTKPLPIKTF
                     KLLTNKWIH"
     gene            complement(<547910..>549346)
                     /locus_tag="YHR214C-C"
                     /db_xref="GeneID:856624"
     mRNA            complement(<547910..>549346)
                     /locus_tag="YHR214C-C"
                     /product="gag protein"
                     /transcript_id="NM_001184437.3"
                     /db_xref="GI:398365190"
                     /db_xref="GeneID:856624"
     CDS             complement(547910..549346)
                     /locus_tag="YHR214C-C"
                     /note="Retrotransposon TYA Gag gene co-transcribed with
                     TYB Pol; translated as TYA or TYA-TYB polyprotein; Gag is
                     a nucleocapsid protein that is the structural constituent
                     of virus-like particles (VLPs); similar to retroviral Gag"
                     /codon_start=1
                     /product="gag protein"
                     /protein_id="NP_036195.3"
                     /db_xref="GI:398365191"
                     /db_xref="SGD:S000007421"
                     /db_xref="GeneID:856624"
                     /translation="MESQQLSNYPHISHGSACASVTSKEVHTNQDPLDVSASKIQEYD
                     KASTKANSQQTTTPASSAVPENLHHASPQPASVPPPQNGPYPQQCMMTQNQANPSGWS
                     FYGHPSMIPYTPYQMSPMYFPPGPQSQFPQYPSSVGTPLSTPSPESGNTFTDSSSADS
                     DMTSTKKYVRPPPMLTSPNDFPNWVKTYIKFLQNSNLGGIIPTVNGKPVPPMLTSPND
                     FPNWVKTYIKFLQNSNLGGIIPTVNGKPVRQITDDELTFLYNTFQIFAPSQFLPTWVK
                     DILSVDYTDIMKILSKSIEKMQSDTQEANDIVTLANLQYNGSTPADAFETKVTNIIDR
                     LNNNGIHINNKVACQLIMRGLSGEYKFLRYTRHRHLNMTVAELFLDIHAIYEEQQGSR
                     NSKPNYRRNPSDEKNDSRSYTNTTKPKVIARNPQKTNNSKSKTARAHNVSTSNNSPST
                     DNDSISKSTTEPIQLNNKHDLHLRPETY"
     LTR             complement(549306..549637)
                     /note="Ty1 LTR"
                     /db_xref="SGD:S000007002"
     gene            complement(<550648..>550941)
                     /locus_tag="YHR214C-D"
                     /db_xref="GeneID:1466534"
     mRNA            complement(<550648..>550941)
                     /locus_tag="YHR214C-D"
                     /product="hypothetical protein"
                     /transcript_id="NM_001184601.1"
                     /db_xref="GI:296145596"
                     /db_xref="GeneID:1466534"
     CDS             complement(550648..550941)
                     /locus_tag="YHR214C-D"
                     /note="hypothetical protein; identified by gene-trapping,
                     microarray-based expression analysis, and genome-wide
                     homology searching; YHR214C-D has a paralog, YAR069C, that
                     arose from a segmental duplication"
                     /codon_start=1
                     /product="hypothetical protein"
                     /protein_id="NP_878094.1"
                     /db_xref="GI:33438812"
                     /db_xref="SGD:S000028653"
                     /db_xref="GeneID:1466534"
                     /translation="MEDHTLVAIVVFFGNGEPFHVSLSVEMVFVLLLSSTRIHEVVVL
                     ICYKLQHATWSWGNMSKNFSLKPDISLSFLLDIISINDICIYGCIALTVVFIL"
     gene            complement(<551200..>551499)
                     /locus_tag="YHR214C-E"
                     /db_xref="GeneID:1466535"
     mRNA            complement(<551200..>551499)
                     /locus_tag="YHR214C-E"
                     /product="hypothetical protein"
                     /transcript_id="NM_001184602.3"
                     /db_xref="GI:398365202"
                     /db_xref="GeneID:1466535"
     CDS             complement(551200..551499)
                     /locus_tag="YHR214C-E"
                     /note="hypothetical protein; identified by gene-trapping,
                     microarray-based expression analysis, and genome-wide
                     homology searching"
                     /codon_start=1
                     /product="hypothetical protein"
                     /protein_id="NP_878095.3"
                     /db_xref="GI:398365203"
                     /db_xref="SGD:S000028654"
                     /db_xref="GeneID:1466535"
                     /translation="MYKITTIYLWLKSYLSFFIGLDNLDFLTLIRFFQCRLQNKLGLQ
                     DILDFFCNLCGHSMVRTCNMVEAAQKQNRITFGSIYVKLHPLVKLCTGIVWAPRV"
     gene            <552099..>553502
                     /gene="PHO12"
                     /locus_tag="YHR215W"
                     /gene_synonym="PHO10"
                     /db_xref="GeneID:856625"
     mRNA            <552099..>553502
                     /gene="PHO12"
                     /locus_tag="YHR215W"
                     /gene_synonym="PHO10"
                     /product="acid phosphatase PHO12"
                     /transcript_id="NM_001179346.1"
                     /db_xref="GI:296145598"
                     /db_xref="GeneID:856625"
     CDS             552099..553502
                     /gene="PHO12"
                     /locus_tag="YHR215W"
                     /gene_synonym="PHO10"
                     /EC_number="3.1.3.2"
                     /note="One of three repressible acid phosphatases;
                     glycoprotein that is transported to the cell surface by
                     the secretory pathway; pregulated by phosphate starvation;
                     PHO12 has a paralog, PHO11, that arose from a segmental
                     duplication"
                     /codon_start=1
                     /product="acid phosphatase PHO12"
                     /protein_id="NP_012087.1"
                     /db_xref="GI:6322011"
                     /db_xref="SGD:S000001258"
                     /db_xref="GeneID:856625"
                     /translation="MLKSAVYSILAASLVNAGTIPLGKLSDIDKIGTQTEIFPFLGGS
                     GPYYSFPGDYGISRDLPESCEMKQVQMVGRHGERYPTVSKAKSIMTTWYKLSNYTGQF
                     SGALSFLNDDYEFFIRDTKNLEMETTLANSVNVLNPYTGEMNAKRHARDFLAQYGYMV
                     ENQTSFAVFTSNSNRCHDTAQYFIDGLGDKFNISLQTISEAESAGANTLSAHHSCPAW
                     DDDVNDDILKKYDTKYLSGIAKRLNKENKGLNLTSSDANTFFAWCAYEINARGYSDIC
                     NIFTKDELVRFSYGQDLETYYQTGPGYDVVRSVGANLFNASVKLLKESEVQDQKVWLS
                     FTHDTDILNYLTTIGIIDDQNNLTAEHVPFMENTFHRSWYVPQGARVYTEKFQCSNDT
                     YVRYVINDAVVPIETCSTGPGFSCEINDFYGYAEKRVAGTDFLKVCNVSSVSNSTELT
                     FFWDWNTKHYNDTLLKQ"
     gene            <554396..>555967
                     /gene="IMD2"
                     /locus_tag="YHR216W"
                     /gene_synonym="PUR5"
                     /db_xref="GeneID:856626"
     mRNA            <554396..>555967
                     /gene="IMD2"
                     /locus_tag="YHR216W"
                     /gene_synonym="PUR5"
                     /product="IMP dehydrogenase IMD2"
                     /transcript_id="NM_001179347.3"
                     /db_xref="GI:398365224"
                     /db_xref="GeneID:856626"
     CDS             554396..555967
                     /gene="IMD2"
                     /locus_tag="YHR216W"
                     /gene_synonym="PUR5"
                     /EC_number="1.1.1.205"
                     /note="Inosine monophosphate dehydrogenase; catalyzes the
                     rate-limiting step in GTP biosynthesis, expression is
                     induced by mycophenolic acid resulting in resistance to
                     the drug, expression is repressed by nutrient limitation;
                     IMD2 has a paralog, YAR073W/YAR075W, that arose from a
                     segmental duplication"
                     /codon_start=1
                     /product="IMP dehydrogenase IMD2"
                     /protein_id="NP_012088.3"
                     /db_xref="GI:398365225"
                     /db_xref="SGD:S000001259"
                     /db_xref="GeneID:856626"
                     /translation="MAAIRDYKTALDFTKSLPRPDGLSVQELMDSKIRGGLTYNDFLI
                     LPGLVDFASSEVSLQTKLTRNITLNIPLVSSPMDTVTESEMATFMALLGGIGFIHHNC
                     TPEDQADMVRRVKNYENGFINNPIVISPTTTVGEAKSMKEKYGFAGFPVTTDGKRNAK
                     LVGVITSRDIQFVEDNSLLVQDVMTKNPVTGAQGITLSEGNEILKKIKKGRLLVVDEK
                     GNLVSMLSRTDLMKNQNYPLASKSANTKQLLCGASIGTMDADKERLRLLVKAGLDVVI
                     LDSSQGNSIFELNMLKWVKESFPGLEVIAGNVVTREQAANLIAAGADGLRIGMGTGSI
                     CITQEVMACGRPQGTAVYNVCEFANQFGVPCMADGGVQNIGHITKALALGSSTVMMGG
                     MLAGTTESPGEYFYQDGKRLKAYRGMGSIDAMQKTGTKGNASTSRYFSESDSVLVAQG
                     VSGAVVDKGSIKKFIPYLYNGLQHSCQDIGCRSLTLLKNNVQRGKVRFEFRTASAQLE
                     GGVHNLHSYEKRLHN"
     rep_origin      556001..556331
                     /note="ARS824;
                     Autonomously Replicating Sequence"
                     /db_xref="SGD:S000118363"
     telomere        556105..562643
                     /note="TEL08R; Telomeric region on the right arm of
                     Chromosome VIII; composed of an X element core sequence, X
                     element combinatorial repeats, an internal stretch of
                     telomeric repeats, a short Y' element, and a terminal
                     stretch of telomeric repeats"
                     /db_xref="SGD:S000028964"
     gene            <558014..>559924
                     /locus_tag="YHR218W"
                     /db_xref="GeneID:856628"
     mRNA            join(<558014..558615,558715..>559924)
                     /locus_tag="YHR218W"
                     /product="hypothetical protein"
                     /transcript_id="NM_001179349.1"
                     /db_xref="GI:296145600"
                     /db_xref="GeneID:856628"
     CDS             join(558014..558615,558715..559924)
                     /locus_tag="YHR218W"
                     /note="Helicase-like protein encoded within the telomeric
                     Y' element"
                     /codon_start=1
                     /product="hypothetical protein"
                     /protein_id="NP_012090.1"
                     /db_xref="GI:6322014"
                     /db_xref="SGD:S000001261"
                     /db_xref="GeneID:856628"
                     /translation="MDRKRSFEKIVVSVMVGKNVQKFLTFVEDEPDFQGGPIPSKYLI
                     PKKINLMVYTLFQVHTLKFNRKDYDTLSLFYLNRGYYNELSFRVLERCYEIASARPND
                     SSTMRTFTDFVSGTPIVRSLQKSTIRKYGYNLAPYMFLLLHVDELSIFSAYQASLPGE
                     KKVDTERLKRDLCPRKPTEIKYFSQICNDMMNKKDRLGDVLATAQRIRRRYNKNGSSE
                     PRLKTLDGLTSERWIQWLGLESDYHCSFSSTRNAEDVVAGEAASSDHDQKISRVTRKR
                     PREPKSTNDILVAGRKLFGSSFEFRDLHQLRLCHEIYMADTPSVAVQAPPGYGKTELF
                     HLPLIALASKGDVKYVSFLFVPYTVLLANCMIRLGRRGCLNVAPVRNFIEEGCDGVTD
                     LYVGIYDDLASTNFTDRIAAWENIVECTFRTNNVKLGYLIVDEFHNFETEVYRQSQFG
                     GITNLDFDAFEKAIFLSGTAPEAVADAALQRIGLTGLAKKSMDINELKRSEDLSRGLS
                     SYPTRMFNLIKEKSEVPLGHVHKIWKKVESQPEEALKLLLALFEIEPESKAIVVASTT
                     NEVEELACSWRKYFRVVWIHGKLGCCRKGVSHKGVCH"
     gene            <560173..>562047
                     /locus_tag="YHR219W"
                     /db_xref="GeneID:856629"
     mRNA            <560173..>562047
                     /locus_tag="YHR219W"
                     /product="hypothetical protein"
                     /transcript_id="NM_001179350.3"
                     /db_xref="GI:398365242"
                     /db_xref="GeneID:856629"
     CDS             560173..562047
                     /locus_tag="YHR219W"
                     /note="hypothetical protein with similarity to helicases;
                     located in the telomere region on the right arm of
                     chromosome VIII"
                     /codon_start=1
                     /product="hypothetical protein"
                     /protein_id="NP_012091.3"
                     /db_xref="GI:398365243"
                     /db_xref="SGD:S000001262"
                     /db_xref="GeneID:856629"
                     /translation="MDLNQRKEKKGQHVGCCGSRTDLSADTVELIERMDRLAENQATA
                     SMSIVALPSSFQESNSSDRCRKYCSSDEDSDTCIHGSANASTNATTNSSTNATTTASI
                     NVRTSATTTASINVRTSATTTESTNSNTNATTTESTNSSTNATTTASINVRTSATTTE
                     STNSNTSATTTESTDSNTSATTTESTDSNTSATTTASTNSSTNATTTASTNSSTNATT
                     TESTNASAKEDANKDGNAEDNRFHPVTDINKESYKRKGSQMVLLERKKLKAQFPNTSE
                     NMNVLQFLGFRSDEIKHLFLYGIDIYFCPEGVFTQYGLCKGCQKMFELCVCWAGQKVS
                     YRRMAWEALAVERMLRNDEEYKEYLEDIEPYHGDPVGYLKFFSVKRGEIYSQIQRNYA
                     WYLAITRRRETISVLDSTRGKQGSQVFRMSGRQIKELYYKVWSNLRESKTEVLQYFLN
                     WDEKKCREEWEAKDDTVFVEALEKVGVFQRLRSMTSAGLQGPQYVKLQFSRHHRQLRS
                     RYELSLGMHLRDQLALGVTPSKVPHWTAFLSMLIGLFYNKTFRQKLEYLLEQISEVWL
                     LPHWVDLANVEVLAADNTRVPLYMLMVAVHKELDSDDVPDGRFDIILLCRDSSREVGE
                     "
CONTIG      join(BK006934.2:1..562643)
//
DBGET integrated database retrieval system