GenomeNet

Database: RefSeq
Entry: NC_001143
LinkDB: NC_001143
Original site: NC_001143 
LOCUS       NC_001143             666816 bp    DNA     linear   CON 15-JUN-2015
DEFINITION  Saccharomyces cerevisiae S288c chromosome XI, complete sequence.
ACCESSION   NC_001143
VERSION     NC_001143.9  GI:330443667
DBLINK      BioProject: PRJNA128
            Assembly: GCF_000146045.2
KEYWORDS    RefSeq.
SOURCE      Saccharomyces cerevisiae S288c
  ORGANISM  Saccharomyces cerevisiae S288c
            Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina;
            Saccharomycetes; Saccharomycetales; Saccharomycetaceae;
            Saccharomyces.
REFERENCE   1  (bases 1 to 666816)
  AUTHORS   Goffeau,A., Barrell,B.G., Bussey,H., Davis,R.W., Dujon,B.,
            Feldmann,H., Galibert,F., Hoheisel,J.D., Jacq,C., Johnston,M.,
            Louis,E.J., Mewes,H.W., Murakami,Y., Philippsen,P., Tettelin,H. and
            Oliver,S.G.
  TITLE     Life with 6000 genes
  JOURNAL   Science 274 (5287), 546 (1996)
   PUBMED   8849441
REFERENCE   2  (bases 1 to 666816)
  AUTHORS   Dujon,B., Alexandraki,D., Andre,B., Ansorge,W., Baladron,V.,
            Ballesta,J.P., Banrevi,A., Bolle,P.A., Bolotin-Fukuhara,M.,
            Bossier,P. et al.
  TITLE     Complete DNA sequence of yeast chromosome XI
  JOURNAL   Nature 369 (6479), 371-378 (1994)
   PUBMED   8196765
REFERENCE   3  (bases 1 to 666816)
  CONSRTM   NCBI Genome Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2015) National Center for Biotechnology
            Information, NIH, Bethesda, MD 20894, USA
REFERENCE   4  (bases 1 to 666816)
  CONSRTM   Saccharomyces Genome Database
  TITLE     Direct Submission
  JOURNAL   Submitted (04-MAY-2012) Department of Genetics, Stanford
            University, Stanford, CA 94305-5120, USA
  REMARK    Protein update by submitter
REFERENCE   5  (bases 1 to 666816)
  CONSRTM   Saccharomyces Genome Database
  TITLE     Direct Submission
  JOURNAL   Submitted (31-MAR-2011) Department of Genetics, Stanford
            University, Stanford, CA 94305-5120, USA
  REMARK    Sequence update by submitter
REFERENCE   6  (bases 1 to 666816)
  CONSRTM   Saccharomyces Genome Database
  TITLE     Direct Submission
  JOURNAL   Submitted (14-DEC-2009) Department of Genetics, Stanford
            University, Stanford, CA 94305-5120, USA
COMMENT     REVIEWED REFSEQ: This record has been curated by SGD. The reference
            sequence is identical to BK006944.
            On Apr 26, 2011 this sequence version replaced gi:269970310.
            Chromosome XI sequence was verified by resequencing.  The sequence
            was mapped to the previous GenBank records except for a 500 bp
            region.  That region was determined by sequencing a descendant of
            the S288c strain, AB972, and is present in GenBank as JF740677.
            Sequence assembly version R64-2-1.
FEATURES             Location/Qualifiers
     source          1..666816
                     /organism="Saccharomyces cerevisiae S288c"
                     /mol_type="genomic DNA"
                     /strain="S288c"
                     /db_xref="taxon:559292"
                     /chromosome="XI"
     telomere        complement(1..807)
                     /note="TEL11L; Telomeric region on the left arm of
                     Chromosome XI; composed of an X element core sequence, X
                     element combinatorial repeats, and a short terminal
                     stretch of telomeric repeats"
                     /db_xref="SGD:S000028906"
     gene            complement(<1810..>2181)
                     /gene="PAU16"
                     /locus_tag="YKL224C"
                     /db_xref="GeneID:853656"
     mRNA            complement(<1810..>2181)
                     /gene="PAU16"
                     /locus_tag="YKL224C"
                     /product="seripauperin PAU16"
                     /transcript_id="NM_001179789.1"
                     /db_xref="GI:296146166"
                     /db_xref="GeneID:853656"
     CDS             complement(1810..2181)
                     /gene="PAU16"
                     /locus_tag="YKL224C"
                     /note="hypothetical protein; member of the seripauperin
                     multigene family encoded mainly in subtelomeric regions"
                     /codon_start=1
                     /product="seripauperin PAU16"
                     /protein_id="NP_012698.1"
                     /db_xref="GI:6322625"
                     /db_xref="SGD:S000001707"
                     /db_xref="GeneID:853656"
                     /translation="MVKLTSIAAGVAAIAAGVAAAPATTTLSPSDERVNLVELGVYVS
                     DIRAHLAQYYLFQAAHPSETYPVEIAEAVFNYGDFTTMLTGIPAEQVTRVITGVPWYS
                     TRLRPAISSALSKDGIYTIAN"
     gene            complement(<3503..>5620)
                     /locus_tag="YKL222C"
                     /db_xref="GeneID:853658"
     mRNA            complement(<3503..>5620)
                     /locus_tag="YKL222C"
                     /product="hypothetical protein"
                     /transcript_id="NM_001179787.1"
                     /db_xref="GI:296146167"
                     /db_xref="GeneID:853658"
     CDS             complement(3503..5620)
                     /locus_tag="YKL222C"
                     /note="hypothetical protein; may interact with ribosomes,
                     based on co-purification experiments; similar to
                     transcriptional regulators from the zinc cluster
                     (binuclear cluster) family; null mutant is sensitive to
                     caffeine"
                     /codon_start=1
                     /product="hypothetical protein"
                     /protein_id="NP_012700.1"
                     /db_xref="GI:6322627"
                     /db_xref="SGD:S000001705"
                     /db_xref="GeneID:853658"
                     /translation="MKNTELSQKKKLDRQSRRKPAKSCHFCRVRKLKCDRVRPFCGSC
                     SSRNRKQCEYKENTSAMEDQLRKKYRRCSKLEMARRIEELESQLTKQSQPNIHEGQNP
                     LSNMRYLSSKHNRHILYGPTSYRAILATQTDTFAKYREEIWQVLKLSRNNWKREHHYS
                     TLSEISSIETAPPHSGSPSVIEYLCESLPNYEVLCEYLTDFFASDFYDSYQIVHKEKV
                     LRDLQDCFVKGPRSHKTGQHTIISLNLDSKKNYYKVGVMTAIMCLASHPKEVPEAIEV
                     FHKVLTSFVSAKVFYTERVQFLFLRYLYINVAGLDGGDQSHCIFIHGLTIDTAIHMGL
                     NEDLRRLYLSKNHPIEEIPYLERLWLWILFTDVKISLSTGIPVRINDDFVNKVRLENY
                     SSSGDILLYKTTLRLRNIMKQIHAREKPPDIPLIIEDLKKFTIKMFKPLDFYLNASNL
                     NGNEFTELQLWHATLHMIGSLSNLYTLTHQDFDARIFNFSVLAPLNSLHLCFNVLETY
                     FELDNSKLSSKSLCLSKKWPHLNNALFLIYVNAFRALIQIYTIFLQYMENKDIQLFIQ
                     RNSSALTYSICPGDFEGPHNKCISLKIAFKEMENIFDHIHQEKLKPLTQIWQNSYYFS
                     IIISMEKIGRRAFNKGMKNIDEGPETENDATENSLTTILNDLEGPLEDFSENFIDDIL
                     GSPSAFFDTAISGWSNFEDFFSR"
     gene            <6107..>7528
                     /gene="MCH2"
                     /locus_tag="YKL221W"
                     /db_xref="GeneID:853659"
     mRNA            <6107..>7528
                     /gene="MCH2"
                     /locus_tag="YKL221W"
                     /product="Mch2p"
                     /transcript_id="NM_001179786.2"
                     /db_xref="GI:330443639"
                     /db_xref="GeneID:853659"
     CDS             6107..7528
                     /gene="MCH2"
                     /locus_tag="YKL221W"
                     /note="Protein with similarity to mammalian
                     monocarboxylate permeases; monocarboxylate permeases are
                     involved in transport of monocarboxylic acids across the
                     plasma membrane but mutant is not deficient in
                     monocarboxylate transport"
                     /codon_start=1
                     /product="Mch2p"
                     /protein_id="NP_012701.2"
                     /db_xref="GI:330443640"
                     /db_xref="SGD:S000001704"
                     /db_xref="GeneID:853659"
                     /translation="MSEERHEDHHRDVENKLNLNGKDDINGNTSISIEVPDGGYGWFI
                     LLAFILYNFSTWGANSGYAIYLAHYLENNTFAGGSKLDYASIGGLAFSCGLFFAPVIT
                     WLYHIFSIQFIIGLGILFQGAALLLAAFSVTLWEIYLTQGVLIGFGLAFIFIPSVTLI
                     PLWFRNKRSLASGIGTAGSGLGGIVFNLGMQSILQKRGVKWALIAQCIICTSLSTIAL
                     MLTRTTHQGLRQHKRSYKFELLDYDVLSNFAVWLLFGFVSFAMLGYVVLLYSLSDFTV
                     SLGYTSKQGSYVSCMVSVGSLLGRPIVGHIADKYGSLTVGMILHLVMAILCWAMWIPC
                     KNLATAIAFGLLVGSIMGTIWPTIASIVTRIVGLQKLPGTFGSTWIFMAAFALVAPII
                     GLELRSTDTNGNDYYRTAIFVGFAYFGVSLCQWLLRGFIIARDEIAVREAYSADQNEL
                     HLNVKLSHMSKCLFRYKQLPRRV"
     rep_origin      7528..8309
                     /note="ARS1102;
                     Putative replication origin; identified in multiple array
                     studies, not yet confirmed by plasmid-based assay"
                     /db_xref="SGD:S000130137"
     gene            complement(<9091..>11226)
                     /gene="FRE2"
                     /locus_tag="YKL220C"
                     /db_xref="GeneID:853660"
     mRNA            complement(<9091..>11226)
                     /gene="FRE2"
                     /locus_tag="YKL220C"
                     /product="Fre2p"
                     /transcript_id="NM_001179785.1"
                     /db_xref="GI:296146169"
                     /db_xref="GeneID:853660"
     CDS             complement(9091..11226)
                     /gene="FRE2"
                     /locus_tag="YKL220C"
                     /EC_number="1.16.1.9"
                     /note="Ferric reductase and cupric reductase; reduces
                     siderophore-bound iron and oxidized copper prior to uptake
                     by transporters; expression induced by low iron levels but
                     not by low copper levels"
                     /codon_start=1
                     /product="Fre2p"
                     /protein_id="NP_012702.1"
                     /db_xref="GI:6322629"
                     /db_xref="SGD:S000001703"
                     /db_xref="GeneID:853660"
                     /translation="MHWTSILSAILLFCLSGARASPAKTVIRNKVPLLVTNACTRIFQ
                     KVTWEYTSKSKRSSPVCSYEPAFQSMLYCIYETLDEKGYSNKTLEKTFSTIKKNCASY
                     SDALQNMTNSEFYDVLNNGTRHMTPYVKGSANLTYPVEMDTQLRKAYYHALHGFYANL
                     DVGNIYGGIICAYFVAIMAFAGVLHCMNYTPFKTVLLKQKLVGYVRGYLTLPTIGSKH
                     ASDFSYFRIFTGYLPTRLEGIIILGYLVLHTVFLAYGYEYDPENIIFKSRRVQVARYV
                     ADRSGVLAFAHFPLIVLFAGRNNFLEYISGVKYTSFIMFHKWLGRMMFLDAMIHGSAY
                     TSYTVANKTWATSKNRLYWQFGVAALCLAGTMVFFSFAVFRKYFYEAFLFLHIVLGAM
                     FFYACWEHVVSLSGIEWIYTAIAIWIVDRIIRIIKASYFGFPKASLQLIGDDLIRLTV
                     KKPARPWRAKPGQYVFVSFLHPLYFWQSHPFTVLDSVSKNGELVIILKEKKGVTRLVK
                     KYVCRNGGKTSMRLAIEGPYGSSSPVNNYNNVLLLTGGTGLPGPIAHAIKLGKTSAAA
                     GKQSVKLVIAVRGFDVLEAYKPELMCLENLNVQLHIYNTMEVPSLTPSDSLDISQQDE
                     KADEKGTVVATTLEKSANPLGFDGVVFHCGRPNVKELLHEAAELSGSLSVVCCGPPIF
                     VDKVRNETAKIVLDKSAKAIEYFEEYQCW"
     gene            <14485..>15708
                     /gene="COS9"
                     /locus_tag="YKL219W"
                     /db_xref="GeneID:853661"
     mRNA            <14485..>15708
                     /gene="COS9"
                     /locus_tag="YKL219W"
                     /product="Cos9p"
                     /transcript_id="NM_001179784.1"
                     /db_xref="GI:296146170"
                     /db_xref="GeneID:853661"
     CDS             14485..15708
                     /gene="COS9"
                     /locus_tag="YKL219W"
                     /note="hypothetical protein; member of the DUP380
                     subfamily of conserved, often subtelomerically-encoded
                     proteins"
                     /codon_start=1
                     /product="Cos9p"
                     /protein_id="NP_012703.1"
                     /db_xref="GI:6322630"
                     /db_xref="SGD:S000001702"
                     /db_xref="GeneID:853661"
                     /translation="MQIVRSCNSNNKPLIPSSNWHIAIRMRGDGVKDRSIDVLSLKHF
                     ESQKVVLPQDLFMDNFTWMFYEFFKCFTFRTWLLLLLLMWLPGFLSQIKSINRIFPFK
                     LCILVSCLVGIFLPNIYSFSHKSVLTNQLTQFSKEIVEHAPGTDTHDWETVAANLNSY
                     FYENKAWNTEYFFFNAAECQKAFRKVLLEPFSVKKDESSKIKSFGDSVPYIEEALQVY
                     STEFDKKWKLFNTEKVWSPDNLEHVQLPKKTYRYKFTWVLKRIFNLWLFPAFILFLAC
                     IYVSWDKGHLFRILCCGGGFLLMVRVFQNMRPFSMHMEDKMQFLSTIINEQESGANGW
                     DEIAKKMNRYLFEKKVWTSEEFFFDGIDCEWFFNHFFYRLLSTKKPMFDRPLNVELWP
                     YIKEAQLTRKQAPPV"
     gene            complement(<17359..>18339)
                     /gene="SRY1"
                     /locus_tag="YKL218C"
                     /db_xref="GeneID:853662"
     mRNA            complement(<17359..>18339)
                     /gene="SRY1"
                     /locus_tag="YKL218C"
                     /product="threo-3-hydroxy-L-aspartate ammonia-lyase SRY1"
                     /transcript_id="NM_001179783.1"
                     /db_xref="GI:296146171"
                     /db_xref="GeneID:853662"
     CDS             complement(17359..18339)
                     /gene="SRY1"
                     /locus_tag="YKL218C"
                     /EC_number="4.3.1.16"
                     /note="3-hydroxyaspartate dehydratase; deaminates
                     L-threo-3-hydroxyaspartate to form oxaloacetate and
                     ammonia; required in the presence of hydroxyaspartate;
                     highly similar to mouse serine racemase (Srr) but has no
                     serine racemase activity"
                     /codon_start=1
                     /product="threo-3-hydroxy-L-aspartate ammonia-lyase SRY1"
                     /protein_id="NP_012704.1"
                     /db_xref="GI:6322631"
                     /db_xref="SGD:S000001701"
                     /db_xref="GeneID:853662"
                     /translation="MIVPTYGDVLDASNRIKEYVNKTPVLTSRMLNDRLGAQIYFKGE
                     NFQRVGAFKFRGAMNAVSKLSDEKRSKGVIAFSSGNHAQAIALSAKLLNVPATIVMPE
                     DAPALKVAATAGYGAHIIRYNRYTEDREQIGRQLAAEHGFALIPPYDHPDVIAGQGTS
                     AKELLEEVGQLDALFVPLGGGGLLSGSALAARSLSPGCKIFGVEPEAGNDGQQSFRSG
                     SIVHINTPKTIADGAQTQHLGEYTFAIIRENVDDILTVSDQELVKCMHFLAERMKVVV
                     EPTACLGFAGALLKKEELVGKKVGIILSGGNVDMKRYATLISGKEDGPTI"
     gene            <22234..>24084
                     /gene="JEN1"
                     /locus_tag="YKL217W"
                     /db_xref="GeneID:853663"
     mRNA            <22234..>24084
                     /gene="JEN1"
                     /locus_tag="YKL217W"
                     /product="Jen1p"
                     /transcript_id="NM_001179782.1"
                     /db_xref="GI:296146172"
                     /db_xref="GeneID:853663"
     CDS             22234..24084
                     /gene="JEN1"
                     /locus_tag="YKL217W"
                     /note="Monocarboxylate/proton symporter of the plasma
                     membrane; transport activity is dependent on the pH
                     gradient across the membrane; mediates high-affinity
                     uptake of carbon sources lactate, pyuvate, and acetate,
                     and also of the micronutrient selenite, whose structure
                     mimics that of monocarboxylates; expression and
                     localization are tightly regulated, with transcription
                     repression, mRNA degradation, and protein endocytosis and
                     degradation all occurring in the presence of glucose"
                     /codon_start=1
                     /product="Jen1p"
                     /protein_id="NP_012705.1"
                     /db_xref="GI:6322632"
                     /db_xref="SGD:S000001700"
                     /db_xref="GeneID:853663"
                     /translation="MSSSITDEKISGEQQQPAGRKLYYNTSTFAEPPLVDGEGNPINY
                     EPEVYNPDHEKLYHNPSLPAQSIQDTRDDELLERVYSQDQGVEYEEDEEDKPNLSAAS
                     IKSYALTRFTSLLHIHEFSWENVNPIPELRKMTWQNWNYFFMGYFAWLSAAWAFFCVS
                     VSVAPLAELYDRPTKDITWGLGLVLFVRSAGAVIFGLWTDKSSRKWPYITCLFLFVIA
                     QLCTPWCDTYEKFLGVRWITGIAMGGIYGCASATAIEDAPVKARSFLSGLFFSAYAMG
                     FIFAIIFYRAFGYFRDDGWKILFWFSIFLPILLIFWRLLWPETKYFTKVLKARKLILS
                     DAVKANGGEPLPKANFKQKMVSMKRTVQKYWLLFAYLVVLLVGPNYLTHASQDLLPTM
                     LRAQLGLSKDAVTVIVVVTNIGAICGGMIFGQFMEVTGRRLGLLIACTMGGCFTYPAF
                     MLRSEKAILGAGFMLYFCVFGVWGILPIHLAELAPADARALVAGLSYQLGNLASAAAS
                     TIETQLADRYPLERDASGAVIKEDYAKVMAILTGSVFIFTFACVFVGHEKFHRDLSSP
                     VMKKYINQVEEYEADGLSISDIVEQKTECASVKMIDSNVSKTYEEHIETV"
     gene            <25215..>26159
                     /gene="URA1"
                     /locus_tag="YKL216W"
                     /db_xref="GeneID:853664"
     mRNA            <25215..>26159
                     /gene="URA1"
                     /locus_tag="YKL216W"
                     /product="dihydroorotate dehydrogenase"
                     /transcript_id="NM_001179781.1"
                     /db_xref="GI:296146173"
                     /db_xref="GeneID:853664"
     CDS             25215..26159
                     /gene="URA1"
                     /locus_tag="YKL216W"
                     /EC_number="1.3.98.1"
                     /note="Dihydroorotate dehydrogenase; catalyzes the fourth
                     enzymatic step in the de novo biosynthesis of pyrimidines,
                     converting dihydroorotic acid into orotic acid"
                     /codon_start=1
                     /product="dihydroorotate dehydrogenase"
                     /protein_id="NP_012706.1"
                     /db_xref="GI:6322633"
                     /db_xref="SGD:S000001699"
                     /db_xref="GeneID:853664"
                     /translation="MTASLTTKFLNNTYENPFMNASGVHCMTTQELDELANSKAGAFI
                     TKSATTLEREGNPEPRYISVPLGSINSMGLPNEGIDYYLSYVLNRQKNYPDAPAIFFS
                     VAGMSIDENLNLLRKIQDSEFNGITELNLSCPNVPGKPQVAYDFDLTKETLEKVFAFF
                     KKPLGVKLPPYFDFAHFDIMAKILNEFPLAYVNSINSIGNGLFIDVEKESVVVKPKNG
                     FGGIGGEYVKPTALANVRAFYTRLRPEIKVIGTGGIKSGKDAFEHLLCGASMLQIGTE
                     LQKEGVKIFERIEKELKDIMEAKGYTSIDQFRGKLNSI"
     gene            complement(<26827..>30687)
                     /gene="OXP1"
                     /locus_tag="YKL215C"
                     /db_xref="GeneID:853665"
     mRNA            complement(<26827..>30687)
                     /gene="OXP1"
                     /locus_tag="YKL215C"
                     /product="Oxp1p"
                     /transcript_id="NM_001179780.1"
                     /db_xref="GI:296146174"
                     /db_xref="GeneID:853665"
     CDS             complement(26827..30687)
                     /gene="OXP1"
                     /locus_tag="YKL215C"
                     /EC_number="3.5.2.9"
                     /note="5-oxoprolinase; enzyme is ATP-dependent and
                     functions as a dimer; similar to mouse Oplah gene; green
                     fluorescent protein (GFP)-fusion protein localizes to the
                     cytoplasm; protein abundance increases in response to DNA
                     replication stress"
                     /codon_start=1
                     /product="Oxp1p"
                     /protein_id="NP_012707.1"
                     /db_xref="GI:6322634"
                     /db_xref="SGD:S000001698"
                     /db_xref="GeneID:853665"
                     /translation="MQKGNIRIAIDKGGTFTDCVGNIGTGKQEHDTVIKLLSVDPKNY
                     PDAPLEGIRRLLEVLEHKTIPRGIPLDISNVRSLRMGTTLATNCALERNGERCAFITT
                     KGFKDSLLIGDQTRPDIFNLNIKKVVPLYDTVVEIDERVTLEDFSEDPYFTKSSPNEQ
                     EGILEGNSGEMVRVIKKPDESSVRSILKVLYASGIKSIAIAFLHSYTFPDHERIVGNI
                     AREIGFSHVSLSSEVSPMIKFLPRAHSSVADAYLTPVIKKYLNSISAGLSHAEDTHIQ
                     FMQSDGGLVDGGKFSGLKSILSGPAGGVIGYSSTCYDKNNNIPLIGFDMGGTSTDVSR
                     YGDGRLEHVFETVTAGIIIQSPQLDIHTVAAGGSSILSWKNGLFRVGPDSAAADPGPA
                     AYRKGGPLTITDANLFLGRLVPEFFPKIFGPNEDESLDLETTTLKFRELTDVINKDLN
                     SNLTMEEVAYGFIKVANECMARPVRAITEAKGHVVSQHRLVSFGGAGGQHAIAVADSL
                     GIDTVLIHRYSSILSAYGIFLADVIEENQEPCSFILGEPETILKVKKRFLELSKNSIK
                     NLLSQSFSREDIVLERYLNLRYEGTETSLMILQKYDDQWNFREWFSEAHKKEFGFSFD
                     DKRIIIDDIRIRAIGKSGVRKEKTVDEQLIEISHFKKADVSKDASFTQKAYFDNKWVD
                     TAVFKIDDLPAGTIIEGPAILADGTQTNIILPNSQATILNSHIFIKINQKAAKTLSKS
                     GYELDIDPILLSIFSHRFMDIALQMGTQLRKTSVSTNVKERLDFSCALFDSKGNLVAN
                     APHVPVHLGSMSTCISAQAKLWEGKLKPGDVLITNHPDIGGTHLPDITVITPSFSSTG
                     ELIFYVASRAHHADIGGILPGSVPPNSKELYEEGTAIYSELVVKEGIFQEELIYKLFV
                     EDPGKYPGCSGSRRFSDNISDLKAQVAANTKGIQLIGSLTKEYDLATILKYMAAIQTN
                     ASESIKKMLAKMVEHFGTTKFSGEDRLDDGSLIKLQVIIRPEKEEYIFNFDGTSPQVY
                     GNLNAPEAITNSAILYCLRCLVGEDIPLNQGCLKPLTIKIPAGSLLSPRSGAAVVGGN
                     VLTSQRVTDVILKTFNVMADSQGDCNNFTFGTGGNSGNKTDKQIKGFGYYETICGGSG
                     AGADSWRGSGWNGSDAVHTNMTNTRMTDTEVFERRYPVLLKEFSIRRGSGGKGKYTGG
                     NGVVRDVQFRKAVTASILSERRVIGPHGIKGGQDGSRGENLWVRHSTGALINVGGKNT
                     IYAQPGDRFIIKTPGGGGFGQYKD"
     gene            complement(<31082..>31693)
                     /gene="YRA2"
                     /locus_tag="YKL214C"
                     /db_xref="GeneID:853666"
     mRNA            complement(<31082..>31693)
                     /gene="YRA2"
                     /locus_tag="YKL214C"
                     /product="Yra2p"
                     /transcript_id="NM_001179779.1"
                     /db_xref="GI:296146175"
                     /db_xref="GeneID:853666"
     CDS             complement(31082..31693)
                     /gene="YRA2"
                     /locus_tag="YKL214C"
                     /note="Member of the REF (RNA and export factor binding
                     proteins) family; when overexpressed, can substitute for
                     the function of Yra1p in export of poly(A)+ mRNA from the
                     nucleus"
                     /codon_start=1
                     /product="Yra2p"
                     /protein_id="NP_012708.1"
                     /db_xref="GI:6322635"
                     /db_xref="SGD:S000001697"
                     /db_xref="GeneID:853666"
                     /translation="MDKAFDEIIGNSHTDSSSNHKVTRYRRRDLRNELGPRLGFAPSD
                     AASRSKDRLYREREEPPLPKRIRISKIPLDVSDYTLDDMIKEFGSPIFSKIFDNKEDR
                     TCIYEFEDPEVLEKIVERYNGHELHNAKIEVEIYQPQRKHSRMNAHNRRKQTAQEHGR
                     GRPGSHYRQKPNRVSKKNKGREKNNTPTSVEALDAELDAYMKG"
     gene            complement(<31960..>34107)
                     /gene="DOA1"
                     /locus_tag="YKL213C"
                     /gene_synonym="UFD3; ZZZ4"
                     /db_xref="GeneID:853667"
     mRNA            complement(<31960..>34107)
                     /gene="DOA1"
                     /locus_tag="YKL213C"
                     /gene_synonym="UFD3; ZZZ4"
                     /product="Doa1p"
                     /transcript_id="NM_001179778.1"
                     /db_xref="GI:296146176"
                     /db_xref="GeneID:853667"
     CDS             complement(31960..34107)
                     /gene="DOA1"
                     /locus_tag="YKL213C"
                     /gene_synonym="UFD3; ZZZ4"
                     /note="WD repeat protein required for ubiquitin-mediated
                     protein degradation; forms a complex with Cdc48p; plays a
                     role in controlling cellular ubiquitin concentration; also
                     promotes efficient NHEJ in postdiauxic/stationary phase;
                     facilitates N-terminus-dependent proteolysis of
                     centromeric histone H3 (Cse4p) for faithful chromosome
                     segregation; protein increases in abundance and
                     relocalizes from nucleus to nuclear periphery upon DNA
                     replication stress"
                     /codon_start=1
                     /product="Doa1p"
                     /protein_id="NP_012709.1"
                     /db_xref="GI:6322636"
                     /db_xref="SGD:S000001696"
                     /db_xref="GeneID:853667"
                     /translation="MGYQLSATLKGHDQDVRDVVAVDDSKVASVSRDGTVRLWSKDDQ
                     WLGTVVYTGQGFLNSVCYDSEKELLLFGGKDTMINGVPLFATSGEDPLYTLIGHQGNV
                     CSLSFQDGVVISGSWDKTAKVWKEGSLVYNLQAHNASVWDAKVVSFSENKFLTASADK
                     TIKLWQNDKVIKTFSGIHNDVVRHLAVVDDGHFISCSNDGLIKLVDMHTGDVLRTYEG
                     HESFVYCIKLLPNGDIVSCGEDRTVRIWSKENGSLKQVITLPAISIWSVDCMSNGDII
                     VGSSDNLVRIFSQEKSRWASEDEINELSTQVEKSTISSKTIEFDESKLSPYEILQSPG
                     RKEGQIVVVKSPQGTIEAHQFSNSSWKKVGDVVGAGATGNDKKIEFEGKTYDYVFDVD
                     IEDGKPPLKLPINVSDNPYTAADNFLARYELPMSYRDQVVQFILKNTNGISLDQPNDN
                     ASSSAVSPSKTSVMKVLPVKQYLIMENYNPDTIFNGIVKINSNEKTFDDEILAQIGGA
                     LHDIDESWELLLSFANTIRSNWEIKTPAYDIVRLIVKKLPYSSDIKDYIEEGLGNKNI
                     TLTMLTVRILVNCFNNENWGVKLLESNQVYKSIFETIDTEFSQASAKQSQNLAIAVST
                     LIFNYSALVTKGNSDLELLPIVADAINTKYGPLEEYQECEEAAYRLTVAYGNLATVEP
                     TLRQFANSVTWLANIKRSYGNVPRFKDIFDDLS"
     gene            <34543..>36414
                     /gene="SAC1"
                     /locus_tag="YKL212W"
                     /gene_synonym="RSD1"
                     /db_xref="GeneID:853668"
     mRNA            <34543..>36414
                     /gene="SAC1"
                     /locus_tag="YKL212W"
                     /gene_synonym="RSD1"
                     /product="phosphatidylinositol-3-phosphatase SAC1"
                     /transcript_id="NM_001179777.1"
                     /db_xref="GI:296146177"
                     /db_xref="GeneID:853668"
     CDS             34543..36414
                     /gene="SAC1"
                     /locus_tag="YKL212W"
                     /gene_synonym="RSD1"
                     /EC_number="3.1.3.-"
                     /note="Phosphatidylinositol phosphate (PtdInsP)
                     phosphatase; involved in hydrolysis of PtdIns[4]P in the
                     early and medial Golgi; regulated by interaction with
                     Vps74p; ER localized transmembrane protein which cycles
                     through the Golgi; involved in protein trafficking and
                     processing, secretion, and cell wall maintenance;
                     regulates sphingolipid biosynthesis through the modulation
                     of PtdIns(4)P metabolism"
                     /codon_start=1
                     /product="phosphatidylinositol-3-phosphatase SAC1"
                     /protein_id="NP_012710.1"
                     /db_xref="GI:6322637"
                     /db_xref="SGD:S000001695"
                     /db_xref="GeneID:853668"
                     /translation="MTGPIVYVQNADGIFFKLAEGKGTNDAVIHLANQDQGVRVLGAE
                     EFPVQGEVVKIASLMGFIKLKLNRYAIIANTVEETGRFNGHVFYRVLQHSIVSTKFNS
                     RIDSEEAEYIKLLELHLKNSTFYFSYTYDLTNSLQRNEKVGPAASWKTADERFFWNHY
                     LTEDLRNFAHQDPRIDSFIQPVIYGYAKTVDAVLNATPIVLGLITRRSIFRAGTRYFR
                     RGVDKDGNVGNFNETEQILLAENPESEKIHVFSFLQTRGSVPIYWAEINNLKYKPNLV
                     LGENSLDATKKHFDQQKELYGDNYLVNLVNQKGHELPVKEGYESVVHALNDPKIHYVY
                     FDFHHECRKMQWHRVKLLIDHLEKLGLSNEDFFHKVIDSNGNTVEIVNEQHSVVRTNC
                     MDCLDRTNVVQSVLAQWVLQKEFESADVVATGSTWEDNAPLLTSYQNLWADNADAVSV
                     AYSGTGALKTDFTRTGKRTRLGAFNDFLNSASRYYQNNWTDGPRQDSYDLFLGGFRPH
                     TASIKSPFPDRRPVYIQLIPMIICAALTVLGATIFFPKDRFTSSKNLLYFAGASIVLA
                     LSTKFMFKNGIQFVNWPKLVDVGFLVVHQTHDKEQQFKGLKYAQSPKFSKPDPLKRD"
     gene            complement(<36699..>38153)
                     /gene="TRP3"
                     /locus_tag="YKL211C"
                     /db_xref="GeneID:853669"
     mRNA            complement(<36699..>38153)
                     /gene="TRP3"
                     /locus_tag="YKL211C"
                     /product="bifunctional anthranilate
                     synthase/indole-3-glycerol-phosphate synthase"
                     /transcript_id="NM_001179776.1"
                     /db_xref="GI:296146178"
                     /db_xref="GeneID:853669"
     CDS             complement(36699..38153)
                     /gene="TRP3"
                     /locus_tag="YKL211C"
                     /EC_number="4.1.3.27"
                     /EC_number="4.1.1.48"
                     /note="Indole-3-glycerol-phosphate synthase; forms
                     bifunctional hetero-oligomeric anthranilate
                     synthase:indole-3-glycerol phosphate synthase enzyme
                     complex with Trp2p"
                     /codon_start=1
                     /product="bifunctional anthranilate
                     synthase/indole-3-glycerol-phosphate synthase"
                     /protein_id="NP_012711.1"
                     /db_xref="GI:6322638"
                     /db_xref="SGD:S000001694"
                     /db_xref="GeneID:853669"
                     /translation="MSVHAATNPINKHVVLIDNYDSFTWNVYEYLCQEGAKVSVYRND
                     AITVPEIAALNPDTLLISPGPGHPKTDSGISRDCIRYFTGKIPVFGICMGQQCMFDVF
                     GGEVAYAGEIVHGKTSPISHDNCGIFKNVPQGIAVTRYHSLAGTESSLPSCLKVTAST
                     ENGIIMGVRHKKYTVEGVQFHPESILTEEGHLMIRNILNVSGGTWEENKSSPSNSILD
                     RIYARRKIDVNEQSKIPGFTFQDLQSNYDLGLAPPLQDFYTVLSSSHKRAVVLAEVKR
                     ASPSKGPICLKAVAAEQALKYAEAGASAISVLTEPHWFHGSLQDLVNVRKILDLKFPP
                     KERPCVLRKEFIFSKYQILEARLAGADTVLLIVKMLSQPLLKELYSYSKDLNMEPLVE
                     VNSKEELQRALEIGAKVVGVNNRDLHSFNVDLNTTSNLVESIPKDVLLIALSGITTRD
                     DAEKYKKEGVHGFLVGEALMKSTDVKKFIHELCE"
     gene            38811..38911
                     /locus_tag="snR64"
                     /db_xref="GeneID:9164917"
     ncRNA           38811..38911
                     /locus_tag="snR64"
                     /ncRNA_class="snoRNA"
                     /product="SNR64"
                     /note="C/D box small nucleolar RNA (snoRNA); guides
                     2'-O-methylation of large subunit (LSU) rRNA at position
                     C2337"
                     /transcript_id="NR_132199.1"
                     /db_xref="GI:831416124"
                     /db_xref="SGD:S000006455"
                     /db_xref="GeneID:9164917"
     gene            <39163..>42237
                     /gene="UBA1"
                     /locus_tag="YKL210W"
                     /db_xref="GeneID:853670"
     mRNA            <39163..>42237
                     /gene="UBA1"
                     /locus_tag="YKL210W"
                     /product="E1 ubiquitin-activating protein UBA1"
                     /transcript_id="NM_001179775.1"
                     /db_xref="GI:296146179"
                     /db_xref="GeneID:853670"
     CDS             39163..42237
                     /gene="UBA1"
                     /locus_tag="YKL210W"
                     /note="Ubiquitin activating enzyme (E1); involved in
                     ubiquitin-mediated protein degradation and essential for
                     viability; protein abundance increases in response to DNA
                     replication stress"
                     /codon_start=1
                     /product="E1 ubiquitin-activating protein UBA1"
                     /protein_id="NP_012712.1"
                     /db_xref="GI:6322639"
                     /db_xref="SGD:S000001693"
                     /db_xref="GeneID:853670"
                     /translation="MSSNNSGLSAAGEIDESLYSRQLYVLGKEAMLKMQTSNVLILGL
                     KGLGVEIAKNVVLAGVKSMTVFDPEPVQLADLSTQFFLTEKDIGQKRGDVTRAKLAEL
                     NAYVPVNVLDSLDDVTQLSQFQVVVATDTVSLEDKVKINEFCHSSGIRFISSETRGLF
                     GNTFVDLGDEFTVLDPTGEEPRTGMVSDIEPDGTVTMLDDNRHGLEDGNFVRFSEVEG
                     LDKLNDGTLFKVEVLGPFAFRIGSVKEYGEYKKGGIFTEVKVPRKISFKSLKQQLSNP
                     EFVFSDFAKFDRAAQLHLGFQALHQFAVRHNGELPRTMNDEDANELIKLVTDLSVQQP
                     EVLGEGVDVNEDLIKELSYQARGDIPGVVAFFGGLVAQEVLKACSGKFTPLKQFMYFD
                     SLESLPDPKNFPRNEKTTQPVNSRYDNQIAVFGLDFQKKIANSKVFLVGSGAIGCEML
                     KNWALLGLGSGSDGYIVVTDNDSIEKSNLNRQFLFRPKDVGKNKSEVAAEAVCAMNPD
                     LKGKINAKIDKVGPETEEIFNDSFWESLDFVTNALDNVDARTYVDRRCVFYRKPLLES
                     GTLGTKGNTQVIIPRLTESYSSSRDPPEKSIPLCTLRSFPNKIDHTIAWAKSLFQGYF
                     TDSAENVNMYLTQPNFVEQTLKQSGDVKGVLESISDSLSSKPHNFEDCIKWARLEFEK
                     KFNHDIKQLLFNFPKDAKTSNGEPFWSGAKRAPTPLEFDIYNNDHFHFVVAGASLRAY
                     NYGIKSDDSNSKPNVDEYKSVIDHMIIPEFTPNANLKIQVNDDDPDPNANAANGSDEI
                     DQLVSSLPDPSTLAGFKLEPVDFEKDDDTNHHIEFITACSNCRAQNYFIETADRQKTK
                     FIAGRIIPAIATTTSLVTGLVNLELYKLIDNKTDIEQYKNGFVNLALPFFGFSEPIAS
                     PKGEYNNKKYDKIWDRFDIKGDIKLSDLIEHFEKDEGLEITMLSYGVSLLYASFFPPK
                     KLKERLNLPITQLVKLVTKKDIPAHVSTMILEICADDKEGEDVEVPFITIHL"
     gene            complement(<42423..>46295)
                     /gene="STE6"
                     /locus_tag="YKL209C"
                     /db_xref="GeneID:853671"
     mRNA            complement(<42423..>46295)
                     /gene="STE6"
                     /locus_tag="YKL209C"
                     /product="ATP-binding cassette alpha-factor transporter
                     STE6"
                     /transcript_id="NM_001179774.1"
                     /db_xref="GI:296146180"
                     /db_xref="GeneID:853671"
     CDS             complement(42423..46295)
                     /gene="STE6"
                     /locus_tag="YKL209C"
                     /EC_number="3.6.3.48"
                     /note="Plasma membrane ATP-binding cassette (ABC)
                     transporter; required for the export of a-factor,
                     catalyzes ATP hydrolysis coupled to a-factor transport;
                     contains 12 transmembrane domains and two ATP binding
                     domains; expressed only in MATa cells"
                     /codon_start=1
                     /product="ATP-binding cassette alpha-factor transporter
                     STE6"
                     /protein_id="NP_012713.1"
                     /db_xref="GI:6322640"
                     /db_xref="SGD:S000001692"
                     /db_xref="GeneID:853671"
                     /translation="MNFLSFKTTKHYHIFRYVNIRNDYRLLMIMIIGTVATGLVPAIT
                     SILTGRVFDLLSVFVANGSHQGLYSQLVQRSMAVMALGAASVPVMWLSLTSWMHIGER
                     QGFRIRSQILEAYLEEKPMEWYDNNEKLLGDFTQINRCVEELRSSSAEASAITFQNLV
                     AICALLGTSFYYSWSLTLIILCSSPIITFFAVVFSRMIHVYSEKENSETSKAAQLLTW
                     SMNAAQLVRLYCTQRLERKKFKEIILNCNTFFIKSCFFVAANAGILRFLTLTMFVQGF
                     WFGSAMIKKGKLNINDVITCFHSCIMLGSTLNNTLHQIVVLQKGGVAMEKIMTLLKDG
                     SKRNPLNKTVAHQFPLDYATSDLTFANVSFSYPSRPSEAVLKNVSLNFSAGQFTFIVG
                     KSGSGKSTLSNLLLRFYDGYNGSISINGHNIQTIDQKLLIENITVVEQRCTLFNDTLR
                     KNILLGSTDSVRNADCSTNENRHLIKDACQMALLDRFILDLPDGLETLIGTGGVTLSG
                     GQQQRVAIARAFIRDTPILFLDEAVSALDIVHRNLLMKAIRHWRKGKTTIILTHELSQ
                     IESDDYLYLMKEGEVVESGTQSELLADPTTTFSTWYHLQNDYSDAKTIVDTETEEKSI
                     HTVESFNSQLETPKLGSCLSNLGYDETDQLSFYEAIYQKRSNVRTRRVKVEEENIGYA
                     LKQQKNTESSTGPQLLSIIQIIKRMIKSIRYKKILILGLLCSLIAGATNPVFSYTFSF
                     LLEGIVPSTDGKTGSSHYLAKWSLLVLGVAAADGIFNFAKGFLLDCCSEYWVMDLRNE
                     VMEKLTRKNMDWFSGENNKASEISALVLNDLRDLRSLVSEFLSAMTSFVTVSTIGLIW
                     ALVSGWKLSLVCISMFPLIIIFSAIYGGILQKCETDYKTSVAQLENCLYQIVTNIKTI
                     KCLQAEFHFQLTYHDLKIKMQQIASKRAIATGFGISMTNMIVMCIQAIIYYYGLKLVM
                     IHEYTSKEMFTTFTLLLFTIMSCTSLVSQIPDISRGQRAASWIYRILDEKHNTLEVEN
                     NNARTVGIAGHTYHGKEKKPIVSIQNLTFAYPSAPTAFVYKNMNFDMFCGQTLGIIGE
                     SGTGKSTLVLLLTKLYNCEVGKIKIDGTDVNDWNLTSLRKEISVVEQKPLLFNGTIRD
                     NLTYGLQDEILEIEMYDALKYVGIHDFVISSPQGLDTRIDTTLLSGGQAQRLCIARAL
                     LRKSKILILDECTSALDSVSSSIINEIVKKGPPALLTMVITHSEQMMRSCNSIAVLKD
                     GKVVERGNFDTLYNNRGELFQIVSNQSS"
     gene            complement(46735..46806)
                     /gene="TRT2"
                     /locus_tag="tT(CGU)K"
                     /db_xref="GeneID:853672"
     tRNA            complement(46735..46806)
                     /gene="TRT2"
                     /locus_tag="tT(CGU)K"
                     /product="tRNA-Thr"
                     /note="Threonine tRNA (tRNA-Thr), predicted by tRNAscan-SE
                     analysis; correct folding and efficient aminoacylation
                     require Lhp1p"
                     /db_xref="SGD:S000006748"
                     /db_xref="GeneID:853672"
     gene            <47157..>47972
                     /gene="CBT1"
                     /locus_tag="YKL208W"
                     /gene_synonym="SOC1"
                     /db_xref="GeneID:853673"
     mRNA            <47157..>47972
                     /gene="CBT1"
                     /locus_tag="YKL208W"
                     /gene_synonym="SOC1"
                     /product="Cbt1p"
                     /transcript_id="NM_001179773.1"
                     /db_xref="GI:296146181"
                     /db_xref="GeneID:853673"
     CDS             47157..47972
                     /gene="CBT1"
                     /locus_tag="YKL208W"
                     /gene_synonym="SOC1"
                     /note="Protein involved in 5' RNA end processing;
                     substrates include mitochondrial COB, 15S_rRNA, and RPM1
                     transcripts; may also have a role in 3' end processing of
                     the COB pre-mRNA; displays genetic interaction with cell
                     cycle-regulated kinase Dbf2p"
                     /codon_start=1
                     /product="Cbt1p"
                     /protein_id="NP_012714.1"
                     /db_xref="GI:6322641"
                     /db_xref="SGD:S000001691"
                     /db_xref="GeneID:853673"
                     /translation="MVSYGSHSSEVSKVLKTPKFVLRYGNVSSKQRFALKRKINYKLR
                     ESKYQEYLNEYNTFVLYDWENSGAGSLVDSSYNLPSLWKEFITEGISKGAINDKLPTV
                     FMKRKLTNSALGHCLGLDFLTDPSESEHEYRCMFQTVQDIPSLSQLILFNSMPNVPVR
                     LKLHTIGININFGCKRSLISNGGDQDTEMSEAVSYIQPLLEESSRMYRNLNYWKLLKI
                     ARNNKKDEPLDQSTRIKSQVKLLLSQLATNRITSPSVTDHGGHNWLIFTRRRL"
     gene            <48194..>48955
                     /gene="EMC3"
                     /locus_tag="YKL207W"
                     /gene_synonym="AIM27"
                     /db_xref="GeneID:853628"
     mRNA            <48194..>48955
                     /gene="EMC3"
                     /locus_tag="YKL207W"
                     /gene_synonym="AIM27"
                     /product="Emc3p"
                     /transcript_id="NM_001179772.1"
                     /db_xref="GI:296146182"
                     /db_xref="GeneID:853628"
     CDS             48194..48955
                     /gene="EMC3"
                     /locus_tag="YKL207W"
                     /gene_synonym="AIM27"
                     /note="Member of conserved ER transmembrane complex;
                     required for efficient folding of proteins in the ER;
                     required for respiratory growth; null mutant displays
                     induction of the unfolded protein response; homologous to
                     worm Y62E10A.10/EMC-3, fly CG6750, human TMEM111"
                     /codon_start=1
                     /product="Emc3p"
                     /protein_id="NP_012715.3"
                     /db_xref="GI:99030926"
                     /db_xref="SGD:S000001690"
                     /db_xref="GeneID:853628"
                     /translation="MLLDDQLKYWVLLPISIVMVLTGVLKQYIMTLITGSSANEAQPR
                     VKLTEWQYLQWAQLLIGNGGNLSSDAFAAKKEFLVKDLTEERHLAKAKQQDGSQAGEV
                     PNPFNDPSMSNAMMNMAKGNMASFIPQTIIMWWVNHFFAGFILMQLPFPLTAKFKEML
                     QTGIICQDLDVRWVSSISWYFISVLGLNPVYNLIGLNDQDMGIQAGIGGPQGPQGPPQ
                     SQVDKAMHAMANDLTIIQHETCLDNVEQRVLKQYM"
     gene            complement(<49006..>49809)
                     /gene="ADD66"
                     /locus_tag="YKL206C"
                     /gene_synonym="PBA2; POC2"
                     /db_xref="GeneID:853629"
     mRNA            complement(<49006..>49809)
                     /gene="ADD66"
                     /locus_tag="YKL206C"
                     /gene_synonym="PBA2; POC2"
                     /product="Add66p"
                     /transcript_id="NM_001179771.1"
                     /db_xref="GI:296146183"
                     /db_xref="GeneID:853629"
     CDS             complement(49006..49809)
                     /gene="ADD66"
                     /locus_tag="YKL206C"
                     /gene_synonym="PBA2; POC2"
                     /note="Protein involved in 20S proteasome assembly; forms
                     a heterodimer with Pba1p that binds to proteasome
                     precursors; interaction with Pba1p-Add66p may affect
                     function of the mature proteasome and its role in
                     maintaining respiratory metabolism; similar to human PAC2
                     constituent of the PAC1-PAC2 complex involved in
                     proteasome assembly"
                     /codon_start=1
                     /product="Add66p"
                     /protein_id="NP_012716.1"
                     /db_xref="GI:6322643"
                     /db_xref="SGD:S000001689"
                     /db_xref="GeneID:853629"
                     /translation="MSCLVLPLVSVGNIPQLSIDWLLNSQANEWEYLEALDSKYLVEF
                     VGPLDRPEDGSDSLYKDADMKYSSALEVFYNKKRGLFAIQQRTPLVSVNYLNNFIVEI
                     ILPFLSKYNISEICIWDSLYAMEDENGVIVRPQEVYSLGEFYFDDEAELLSNLHLNDQ
                     ESMVNNWLHFTPTSFQDKISVDQPIFKILFQILNASQRPKALRSIKYCSCLANEGDNS
                     LDSQQFLQWIISQKVIKNAPPIVKFVRPISWQGAYGMADARDKFVDLYN"
     gene            <50051..>53353
                     /gene="LOS1"
                     /locus_tag="YKL205W"
                     /db_xref="GeneID:853630"
     mRNA            <50051..>53353
                     /gene="LOS1"
                     /locus_tag="YKL205W"
                     /product="Los1p"
                     /transcript_id="NM_001179770.1"
                     /db_xref="GI:296146184"
                     /db_xref="GeneID:853630"
     CDS             50051..53353
                     /gene="LOS1"
                     /locus_tag="YKL205W"
                     /note="Nuclear pore protein; involved in nuclear export of
                     pre-tRNA and in re-export of mature tRNAs after their
                     retrograde import from the cytoplasm"
                     /codon_start=1
                     /product="Los1p"
                     /protein_id="NP_012717.1"
                     /db_xref="GI:6322644"
                     /db_xref="SGD:S000001688"
                     /db_xref="GeneID:853630"
                     /translation="MLERIQQLVNAVNDPRSDVATKRQAIELLNGIKSSENALEIFIS
                     LVINENSNDLLKFYGLSTLIELMTEGVNANPNGLNLVKFEITKWLKFQVLGNKQTKLP
                     DFLMNKISEVLTTLFMLMYSDCNGNQWNSFFDDLMSLFQVDSAISNTSPSTDGNILLG
                     LEFFNKLCLMINSEIADQSFIRSKESQLKNNNIKDWMRDNDIMKLSNVWFQCLKLDEQ
                     IVSQCPGLINSTLDCIGSFISWIDINLIIDANNYYLQLIYKFLNLKETKISCYNCILA
                     IISKKMKPMDKLAFLNMINLTNELTYYHQAISMNPQIITFDNLEVWESLTKLITSFGI
                     EFTIIIEQVNDDQKLDTLYKQSVISNVDSILLEKIIPILLEFMNNEFDSITAKTFPFW
                     SNYLAFLKKYKASSPNFVPLHKDFLDNFQQICFKRMKFSDDEVTQDDFEEFNETVRFK
                     LKNFQEIIVVIDPSLFLNNISQEISANLMNCKNESWQIFELTIYQIFNLSECTKNNYF
                     GLNKNEIMTSQPSLTLVRFLNELLMMKDFLLAIDNEQIQILFMELIVKNYNFIFSTSA
                     NTANATDDDEKYLLILNIFMSSFAMFNKRENVRLRSWYLFTRFLKLTRINLKKILFAN
                     KNLVNEITNKISPLLHIKVTSINAQGTDDNDTIFDNQLYIFEGIGFIITLNNSSQELT
                     AATANTPIDYDILDQILTPLFTQLEGCITQGASPVVILECHHILMAIGTLARGLHIGL
                     VPENQVNNMVVNKKLINDSLIHKFSNIAEVILVTFSFFNKFENIRDASRFTFARLIPI
                     LSNKILPFINKLIELILSSTDLKSWEMIDFLGFLSQLIHMFHTDTDCYQLFNQLLTPL
                     INKVHSIIEEIDEQHDQQSSSNKPIDTAVTATSVNKNIVVTDSYRDKILLKKAYCTFL
                     QSFTNNSVTSILLSDINRAILPVILNDLVTYTPQEIQETSMMKVSLNVLCNFIKCFGN
                     GTCLDNDDINKDPNLKIDGLNEYFIMKCVPIIFEIPFNPIYKFNIKEGNFKTMAYDLA
                     RLLRELFIVSSNPTTNENECVKYLTQIYLPQIQLPQELTIQLVNMLTTMGQKQFEKWF
                     VDNFISVLKQGQ"
     gene            <53704..>55602
                     /gene="EAP1"
                     /locus_tag="YKL204W"
                     /db_xref="GeneID:853631"
     mRNA            <53704..>55602
                     /gene="EAP1"
                     /locus_tag="YKL204W"
                     /product="Eap1p"
                     /transcript_id="NM_001179769.1"
                     /db_xref="GI:296146185"
                     /db_xref="GeneID:853631"
     CDS             53704..55602
                     /gene="EAP1"
                     /locus_tag="YKL204W"
                     /note="eIF4E-associated protein, competes with eIF4G for
                     binding to eIF4E; accelerates mRNA degradation by
                     promoting decapping, facilitated by interaction with
                     eIF4E; essential for Puf5p mediated repression; associates
                     with Puf5p and Dhh1p; inhibits cap-dependent translation;
                     functions independently of eIF4E to maintain genetic
                     stability; plays a role in cell growth, implicated in the
                     TOR signaling cascade"
                     /codon_start=1
                     /product="Eap1p"
                     /protein_id="NP_012718.1"
                     /db_xref="GI:6322645"
                     /db_xref="SGD:S000001687"
                     /db_xref="GeneID:853631"
                     /translation="MELNDPSIISSSQFSGELSDSDTAAATHKSQQAISNLFQKLAKK
                     GREEKPIGSVESSTDSSNISVATSGNNKESNKKKNKKTAMLNFSSLTDPITNYKPMDL
                     QYKTYAYSMNELYHLKPSLASASYEEDPLISELVRSLPKRKFWRLRMGPPDQKHANNH
                     HFNGNNGGGSWKAGYKNGKNDERRMSRTKNMQGGKRRSQQDDEEKKIDQEMLEMDKNL
                     QLGGDVGHSIADFEDWKAKMKELELKKLSKSKGISNSTAIAPRESASHETPTDLRPVI
                     PRGPSSITDFLNLKRQDKKEESSQQTPGIPVGQPSLSKTSIEQVNELETNSDLGKSSS
                     SRFSSFFNKSATSLPSLDNNNQVPSSNVSVVNNDGNSTPHQSGSRLMSFFKESRSSTP
                     NAESQLLSASDKDNGKMQTLPQFQQQPQQMQPMAFTQHPPNNNAFFNGLLNKGKSETS
                     TPPPPPPGLIAHQGPQFPVMGVPPNFPQRMMPPPPGLVQFQKDSKDVNKKEDRQLRQN
                     KNPNGTRNSKGKQEETATPDLPQQQYMPPPPPPGFFPMHPNFPNGPMPPLPQGFPIPP
                     NGMLPVTGQQPQPPYPNMMLQGNFPPNFQQGFGSNSPMPIPSIINANGKNVTNQLPPG
                     LNSKKNIK"
     rep_origin      55671..55917
                     /note="ARS1103;
                     Autonomously Replicating Sequence"
                     /db_xref="SGD:S000118401"
     gene            complement(<55935..>63359)
                     /gene="TOR2"
                     /locus_tag="YKL203C"
                     /gene_synonym="DRR2"
                     /db_xref="GeneID:853632"
     mRNA            complement(<55935..>63359)
                     /gene="TOR2"
                     /locus_tag="YKL203C"
                     /gene_synonym="DRR2"
                     /product="phosphatidylinositol kinase-related protein
                     kinase TOR2"
                     /transcript_id="NM_001179768.1"
                     /db_xref="GI:296146186"
                     /db_xref="GeneID:853632"
     CDS             complement(55935..63359)
                     /gene="TOR2"
                     /locus_tag="YKL203C"
                     /gene_synonym="DRR2"
                     /EC_number="2.7.11.1"
                     /EC_number="2.7.1.67"
                     /note="PIK-related protein kinase and rapamycin target;
                     subunit of TORC1, a complex that regulates growth in
                     response to nutrients and TORC2, a complex that regulates
                     cell-cycle dependent polarization of the actin
                     cytoskeleton; involved in meiosis; TOR2 has a paralog,
                     TOR1, that arose from the whole genome duplication"
                     /codon_start=1
                     /product="phosphatidylinositol kinase-related protein
                     kinase TOR2"
                     /protein_id="NP_012719.2"
                     /db_xref="GI:42759860"
                     /db_xref="SGD:S000001686"
                     /db_xref="GeneID:853632"
                     /translation="MNKYINKYTTPPNLLSLRQRAEGKHRTRKKLTHKSHSHDDEMST
                     TSNTDSNHNGPNDSGRVITGSAGHIGKISFVDSELDTTFSTLNLIFDKLKSDVPQERA
                     SGANELSTTLTSLAREVSAEQFQRFSNSLNNKIFELIHGFTSSEKIGGILAVDTLISF
                     YLSTEELPNQTSRLANYLRVLIPSSDIEVMRLAANTLGRLTVPGGTLTSDFVEFEVRT
                     CIDWLTLTADNNSSSSKLEYRRHAALLIIKALADNSPYLLYPYVNSILDNIWVPLRDA
                     KLIIRLDAAVALGKCLTIIQDRDPALGKQWFQRLFQGCTHGLSLNTNDSVHATLLVFR
                     ELLSLKAPYLRDKYDDIYKSTMKYKEYKFDVIRREVYAILPLLAAFDPAIFTKKYLDR
                     IMVHYLRYLKNIDMNAANNSDKPFILVSIGDIAFEVGSSISPYMTLILDNIREGLRTK
                     FKVRKQFEKDLFYCIGKLACALGPAFAKHLNKDLLNLMLNCPMSDHMQETLMILNEKI
                     PSLESTVNSRILNLLSISLSGEKFIQSNQYDFNNQFSIEKARKSRNQSFMKKTGESND
                     DITDAQILIQCFKMLQLIHHQYSLTEFVRLITISYIEHEDSSVRKLAALTSCDLFIKD
                     DICKQTSVHALHSVSEVLSKLLMIAITDPVAEIRLEILQHLGSNFDPQLAQPDNLRLL
                     FMALNDEIFGIQLEAIKIIGRLSSVNPAYVVPSLRKTLLELLTQLKFSNMPKKKEESA
                     TLLCTLINSSDEVAKPYIDPILDVILPKCQDASSAVASTALKVLGELSVVGGKEMTRY
                     LKELMPLIINTFQDQSNSFKRDAALTTLGQLAASSGYVVGPLLDYPELLGILINILKT
                     ENNPHIRRGTVRLIGILGALDPYKHREIEVTSNSKSSVEQNAPSIDIALLMQGVSPSN
                     DEYYPTVVIHNLMKILNDPSLSIHHTAAIQAIMHIFQNLGLRCVSFLDQIIPGIILVM
                     RSCPPSQLDFYFQQLGSLISIVKQHIRPHVEKIYGVIREFFPIIKLQITIISVIESIS
                     KALEGEFKRFVPETLTFFLDILENDQSNKRIVPIRILKSLVTFGPNLEDYSHLIMPIV
                     VRMTEYSAGSLKKISIITLGRLAKNINLSEMSSRIVQALVRILNNGDRELTKATMNTL
                     SLLLLQLGTDFVVFVPVINKALLRNRIQHSVYDQLVNKLLNNECLPTNIIFDKENEVP
                     ERKNYEDEMQVTKLPVNQNILKNAWYCSQQKTKEDWQEWIRRLSIQLLKESPSACLRS
                     CSSLVSVYYPLARELFNASFSSCWVELQTSYQEDLIQALCKALSSSENPPEIYQMLLN
                     LVEFMEHDDKPLPIPIHTLGKYAQKCHAFAKALHYKEVEFLEEPKNSTIEALISINNQ
                     LHQTDSAIGILKHAQQHNELQLKETWYEKLQRWEDALAAYNEKEAAGEDSVEVMMGKL
                     RSLYALGEWEELSKLASEKWGTAKPEVKKAMAPLAAGAAWGLEQWDEIAQYTSVMKSQ
                     SPDKEFYDAILCLHRNNFKKAEVHIFNARDLLVTELSALVNESYNRAYNVVVRAQIIA
                     ELEEIIKYKKLPQNSDKRLTMRETWNTRLLGCQKNIDVWQRILRVRSLVIKPKEDAQV
                     RIKFANLCRKSGRMALAKKVLNTLLEETDDPDHPNTAKASPPVVYAQLKYLWATGLQD
                     EALKQLINFTSRMAHDLGLDPNNMIAQSVPQQSKRVPRHVEDYTKLLARCFLKQGEWR
                     VCLQPKWRLSNPDSILGSYLLATHFDNTWYKAWHNWALANFEVISMLTSVSKKKQEGS
                     DASSVTDINEFDNGMIGVNTFDAKEVHYSSNLIHRHVIPAIKGFFHSISLSESSSLQD
                     ALRLLTLWFTFGGIPEATQAMHEGFNLIQIGTWLEVLPQLISRIHQPNQIVSRSLLSL
                     LSDLGKAHPQALVYPLMVAIKSESLSRQKAALSIIEKMRIHSPVLVDQAELVSHELIR
                     MAVLWHEQWYEGLDDASRQFFGEHNTEKMFAALEPLYEMLKRGPETLREISFQNSFGR
                     DLNDAYEWLMNYKKSKDVSNLNQAWDIYYNVFRKIGKQLPQLQTLELQHVSPKLLSAH
                     DLELAVPGTRASGGKPIVKISKFEPVFSVISSKQRPRKFCIKGSDGKDYKYVLKGHED
                     IRQDSLVMQLFGLVNTLLQNDAECFRRHLDIQQYPAIPLSPKSGLLGWVPNSDTFHVL
                     IREHREAKKIPLNIEHWVMLQMAPDYDNLTLLQKVEVFTYALNNTEGQDLYKVLWLKS
                     RSSETWLERRTTYTRSLAVMSMTGYILGLGDRHPSNLMLDRITGKVIHIDFGDCFEAA
                     ILREKFPEKVPFRLTRMLTYAMEVSGIEGSFRITCENVMKVLRDNKGSLMAILEAFAF
                     DPLINWGFDLPTKKIEEETGIQLPVMNANELLSNGAITEEEVQRVENEHKNAIRNARA
                     MLVLKRITDKLTGNDIRRFNDLDVPEQVDKLIQQATSVENLCQHYIGWCPFW"
     gene            complement(<63930..>67466)
                     /gene="MNN4"
                     /locus_tag="YKL201C"
                     /gene_synonym="YKL200C"
                     /db_xref="GeneID:853634"
     mRNA            complement(<63930..>67466)
                     /gene="MNN4"
                     /locus_tag="YKL201C"
                     /gene_synonym="YKL200C"
                     /product="Mnn4p"
                     /transcript_id="NM_001179766.1"
                     /db_xref="GI:296146187"
                     /db_xref="GeneID:853634"
     CDS             complement(63930..67466)
                     /gene="MNN4"
                     /locus_tag="YKL201C"
                     /gene_synonym="YKL200C"
                     /note="Putative positive regulator of mannosylphosphate
                     transferase Mnn6p; involved in mannosylphosphorylation of
                     N-linked oligosaccharides; expression increases in
                     late-logarithmic and stationary growth phases; coding
                     sequence contains length polymorphisms in different
                     strains; MNN4 has a paralog, YJR061W, that arose from the
                     whole genome duplication"
                     /codon_start=1
                     /product="Mnn4p"
                     /protein_id="NP_012721.1"
                     /db_xref="GI:6322648"
                     /db_xref="SGD:S000001684"
                     /db_xref="GeneID:853634"
                     /translation="MLQRISSKLHRRFLSGLLRVKHYPLRRILLPLILLQIIIITFIW
                     SNSPQRNGLGRDADYLLPNYNELDSDDDSWYSILTSSFKNDRKIQFAKTLYENLKFGT
                     NPKWVNEYTLQNDLLSVKMGPRKGSKLESVDELKFYDFDPRLTWSVVLNHLQNNDADQ
                     PEKLPFSWYDWTTFHELNKLISIDKTVLPCNFLFQSAFDKESLEAIETELGEPLFLYE
                     RPKYAQKLWYKAARNQDRIKDSKELKKHCSKLFTPDGHGSPKGLRFNTQFQIKELYDK
                     VRPEVYQLQARNYILTTQSHPLSISIIESDNSTYQVPLQTEKSKNLVQSGLLQEYIND
                     NINSTNKRKKNKQDVEFNHNRLFQEFVNNDQVNSLYKLEIEETDKFTFDKDLVYLSPS
                     DFKFDASKKIEELEEQKKLYPDKFSAHNENYLNSLKNSVKTSPALQRKFFYEAGAVKQ
                     YKGMGFHRDKRFFNVDTLINDKQEYQARLNSMIRTFQKFTKANGIISWLSHGTLYGYL
                     YNGMAFPWDNDFDLQMPIKHLQLLSQYFNQSLILEDPRQGNGRYFLDVSDSLTVRING
                     NGKNNIDARFIDVDTGLYIDITGLASTSAPSRDYLNSYIEERLQEEHLDINNIPESNG
                     ETATLPDKVDDGLVNMATLNITELRDYITSDENKNHKRVPTDTDLKDLLKKELEELPK
                     SKTIENKLNPKQRYFLNEKLKLYNCRNNHFNSFEELSPLINTVFHGVPALIPHRHTYC
                     LHNEYHVPDRYAFDAYKNTAYLPEFRFWFDYDGLKKCSNINSWYPNIPSINSWNPNLL
                     KEISSTKFESKLFDSNKVSEYSFKNLSMDDVRLIYKNIPKAGFIEVFTNLYNSFNVTA
                     YRQKELEIQYCQNLTFIEKKKLLHQLRINVAPKLSSPAKDPFLFGYEKAMWKDLSKSM
                     NQTTLDQVTKIVHEEYVGKIIDLSESLKYRNFSLFNITFDETGTTLDDNTEDYTPANT
                     VEVNPVDFKSNLNFSSNSFLDLNSYGLDLFAPTLSDVNRKGIQMFDKDPIIVYEDYAY
                     AKLLEERKRREKKKKEEEEKKKKEEEEKKKKEEEEKKKKEEEEKKKKEEEEKKKKEEE
                     EKKKQEEEEKKKKEEEEKKKQEEGEKMKNEDEENKKNEDEEKKKNEEEEKKKQEEKNK
                     KNEDEEKKKQEEEEKKKNEEEEKKKQEEGHSN"
     STS             65280..66451
                     /standard_name="ha2182"
                     /db_xref="UniSTS:515503"
     gene            complement(<68232..>70220)
                     /gene="PTK1"
                     /locus_tag="YKL198C"
                     /gene_synonym="KKT8; POT1; STK1; YKL199C; YKT9"
                     /db_xref="GeneID:853635"
     mRNA            complement(<68232..>70220)
                     /gene="PTK1"
                     /locus_tag="YKL198C"
                     /gene_synonym="KKT8; POT1; STK1; YKL199C; YKT9"
                     /product="putative serine/threonine protein kinase PTK1"
                     /transcript_id="NM_001179764.2"
                     /db_xref="GI:330443641"
                     /db_xref="GeneID:853635"
     CDS             complement(68232..70220)
                     /gene="PTK1"
                     /locus_tag="YKL198C"
                     /gene_synonym="KKT8; POT1; STK1; YKL199C; YKT9"
                     /EC_number="2.7.11.1"
                     /note="Putative serine/threonine protein kinase; regulates
                     spermine uptake; involved in polyamine transport; possible
                     mitochondrial protein; PTK1 has a paralog, PTK2, that
                     arose from the whole genome duplication"
                     /codon_start=1
                     /product="putative serine/threonine protein kinase PTK1"
                     /protein_id="NP_012723.3"
                     /db_xref="GI:330443642"
                     /db_xref="SGD:S000001681"
                     /db_xref="GeneID:853635"
                     /translation="MTVSHNHSTKISQQPISSVSAFKFFGKKLLSSSHGNKLKKKASL
                     PPDFHSTSTNDSESSSPKLPNSLKTSRRANSFAHTTNSKRSLSSASTKILPPAGSSTS
                     ISRGNRHSSTSRNLSNSKFSSERLVYNPYGVSTPSTSLSSVSTSMKKDPDLGFYLHDG
                     DSKIRMLPIPIVDPNEYLPDEMKEASIQLSDNFVFDDENKTIGWGGSCEVRKIRSKYR
                     KKDVFALKKLNMIYNETPEKFYKRCSKEFIIAKQLSHHVHITNTFLLVKVPTTVYTTR
                     GWGFVMELGLRDLFAMIQKSGWRSVALAEKFCIFKQVACGVKFCHDQGIAHRDLKPEN
                     VLLSPDGVCKLTDFGISDWYHTDPHDLSSPVKKCAGMIGSPPYAPPEVMFYDSKKHYD
                     TELQQPYDPRALDCYGLGIILMTLVNNVIPFLESCSFDTGFRDYCDAYENFIRLHDRA
                     FRNRGNYRPGPGMEYHLARNFKNGHASRVAWRLADPEAATRYTIDDLFEDPWFQGIET
                     CVDANDKYVCKKPIIKTTTYENPRGFHIATDVAATTPTSNPFLKNRVPIRSMVDIAAH
                     PSPTATVLASSPPPPPPATHVPAEALFTLRETPPPQLATLTLSEEPPATPAPSAPSAP
                     SARVRGHSPHRVVHHHLNIVNSLVHSSSAASSQVPAST"
     gene            complement(<70734..>73865)
                     /gene="PEX1"
                     /locus_tag="YKL197C"
                     /gene_synonym="PAS1"
                     /db_xref="GeneID:853636"
     mRNA            complement(<70734..>73865)
                     /gene="PEX1"
                     /locus_tag="YKL197C"
                     /gene_synonym="PAS1"
                     /product="AAA family ATPase peroxin 1"
                     /transcript_id="NM_001179763.1"
                     /db_xref="GI:296146189"
                     /db_xref="GeneID:853636"
     CDS             complement(70734..73865)
                     /gene="PEX1"
                     /locus_tag="YKL197C"
                     /gene_synonym="PAS1"
                     /note="AAA-peroxin; heterodimerizes with AAA-peroxin Pex6p
                     and participates in the recycling of peroxisomal signal
                     receptor Pex5p from the peroxisomal membrane to the
                     cystosol; induced by oleic acid and upregulated during
                     anaerobiosis"
                     /codon_start=1
                     /product="AAA family ATPase peroxin 1"
                     /protein_id="NP_012724.1"
                     /db_xref="GI:6322651"
                     /db_xref="SGD:S000001680"
                     /db_xref="GeneID:853636"
                     /translation="MTTTKRLKFENLRIQFSNAIVGNFLRLPHSIINVLESTNYAIQE
                     FGIAVHSHNSDIPIVHLGWDGHDSGSSENVVLINPVLATVYDLNQKSPLVDLYIQRYD
                     HTHLATEVYVTPETSDDWEIIDANAMRFQNGEILHQTRIVTPGETLICYLEGIVTKFK
                     IDRVEPSMKSARITDGSLVVVAPKVNKTRLVKAEYGHSNKTILKNGAIQLLKKVILRS
                     TVCKMDFPKDNLFVVYISDGAQLPSQKGYASIVKCSLRQSKKSDSDNKSVGIPSKKIG
                     VFIKCDSQIPENHIALSSHLWDAFFTHPMNGAKIKLEFLQMNQANIISGRNATVNIKY
                     FGKDVPTKSGDQYSKLLGGSLLTNNLILPTEQIIIEIKKGESEQQLCNLNEISNESVQ
                     WKVTQMGKEEVKDIIERHLPKHYHVKETGEVSRTSKDEDDFITVNSIKKEMVNYLTSP
                     IIATPAIILDGKQGIGKTRLLKELINEVEKDHHIFVKYADCETLHETSNLDKTQKLIM
                     EWCSFCYWYGPSLIVLDNVEALFGKPQANDGDPSNNGQWDNASKLLNFFINQVTKIFN
                     KDNKRIRVLFSGKQKTQINPLLFDKHFVSETWSLRAPDKHARAKLLEYFFSKNQIMKL
                     NRDLQFSDLSLETEGFSPLDLEIFTEKIFYDLQLERDCDNVVTRELFSKSLSAFTPSA
                     LRGVKLTKETNIKWGDIGALANAKDVLLETLEWPTKYEPIFVNCPLRLRSGILLYGYP
                     GCGKTLLASAVAQQCGLNFISVKGPEILNKFIGASEQNIRELFERAQSVKPCILFFDE
                     FDSIAPKRGHDSTGVTDRVVNQLLTQMDGAEGLDGVYILAATSRPDLIDSALLRPGRL
                     DKSVICNIPTESERLDILQAIVNSKDKDTGQKKFALEKNADLKLIAEKTAGFSGADLQ
                     GLCYNAYLKSVHRWLSAADQSEVVPGNDNIEYFSINEHGRREENRLRLKTLLQQDVVH
                     ETKTSTSAASELTAVVTINDLLEACQETKPSISTSELVKLRGIYDRFQKDRNGEMPNG
                     ENSIDIGSRLSLM"
     LTR             74236..74518
                     /note="Ty1 LTR"
                     /db_xref="SGD:S000007055"
     gene            74624..74697
                     /locus_tag="tN(GUU)K"
                     /db_xref="GeneID:853637"
     tRNA            74624..74697
                     /locus_tag="tN(GUU)K"
                     /product="tRNA-Asn"
                     /note="Asparagine tRNA (tRNA-Asn), predicted by
                     tRNAscan-SE analysis"
                     /db_xref="SGD:S000006671"
                     /db_xref="GeneID:853637"
     gene            complement(<74932..>75534)
                     /gene="YKT6"
                     /locus_tag="YKL196C"
                     /db_xref="GeneID:853638"
     mRNA            complement(<74932..>75534)
                     /gene="YKT6"
                     /locus_tag="YKL196C"
                     /product="palmitoyltransferase YKT6"
                     /transcript_id="NM_001179762.1"
                     /db_xref="GI:296146190"
                     /db_xref="GeneID:853638"
     CDS             complement(74932..75534)
                     /gene="YKT6"
                     /locus_tag="YKL196C"
                     /EC_number="2.3.1.-"
                     /note="Vesicle membrane protein (v-SNARE) with
                     acyltransferase activity; involved in trafficking to and
                     within the Golgi, endocytic trafficking to the vacuole,
                     and vacuolar fusion; membrane localization due to
                     prenylation at the carboxy-terminus"
                     /codon_start=1
                     /product="palmitoyltransferase YKT6"
                     /protein_id="NP_012725.1"
                     /db_xref="GI:6322652"
                     /db_xref="SGD:S000001679"
                     /db_xref="GeneID:853638"
                     /translation="MRIYYIGVFRSGGEKALELSEVKDLSQFGFFERSSVGQFMTFFA
                     ETVASRTGAGQRQSIEEGNYIGHVYARSEGICGVLITDKEYPVRPAYTLLNKILDEYL
                     VAHPKEEWADVTETNDALKMKQLDTYISKYQDPSQADAIMKVQQELDETKIVLHKTIE
                     NVLQRGEKLDNLVDKSESLTASSKMFYKQAKKSNSCCIIM"
     gene            <75821..>77032
                     /gene="MIA40"
                     /locus_tag="YKL195W"
                     /gene_synonym="FMP15; TIM40"
                     /db_xref="GeneID:853639"
     mRNA            <75821..>77032
                     /gene="MIA40"
                     /locus_tag="YKL195W"
                     /gene_synonym="FMP15; TIM40"
                     /product="Mia40p"
                     /transcript_id="NM_001179761.1"
                     /db_xref="GI:296146191"
                     /db_xref="GeneID:853639"
     CDS             75821..77032
                     /gene="MIA40"
                     /locus_tag="YKL195W"
                     /gene_synonym="FMP15; TIM40"
                     /note="Mitochondrial oxidoreductase; involved in
                     mitochondrial intermembrane space import; component of MIA
                     pathway which mediates import and oxidative folding of
                     substrates including small proteins containing twin
                     cysteine motifs; acts in concert with Erv1p, which
                     oxidizes the cysteine residues of Mia40p to comprise a
                     disulfide relay system that catalyzes import; also
                     mediates folding of Atp23p via a chaperone-like activity;
                     forms a dimer that binds iron-sulfur cluster in vitro"
                     /codon_start=1
                     /product="Mia40p"
                     /protein_id="NP_012726.2"
                     /db_xref="GI:37362671"
                     /db_xref="SGD:S000001678"
                     /db_xref="GeneID:853639"
                     /translation="MLRNLVVRNACRNRPSIQVARGLCRHQTRRLMASSPQFGRNSNQ
                     EKTAGFIMGILSMAGALYFIAPNRKPLFASRKVESDKTAEEELSSGGEQSPENEDDNN
                     SKSDENGDDNDSKNDETEAGPQLGGDKIGASKVAEDGELVVLAEEDNKSSEDKDTDES
                     KVSTKDDEQSNEDNATANNQKDENISSENSEENTSDKTLDNNAGSSEKKDPEHSDDEK
                     SQQGQSDDKTTTEDNNGEEESSKKTVSDSENSAKQSESSDEEKEELRKQEEKQMGPTE
                     EEVQHEGAYNPDTGEINWDCPCLGGMAHGPCGEEFKSAFSCFVYSEAEPKGIDCVEKF
                     QHMQDCFRKYPEHYAEQLKETSDDEEPQDKVKVNTIESAPNVSSAKENAAKKAEQSDV
                     KKEPLNEESKP"
     gene            complement(<77258..>78646)
                     /gene="MST1"
                     /locus_tag="YKL194C"
                     /db_xref="GeneID:853640"
     mRNA            complement(<77258..>78646)
                     /gene="MST1"
                     /locus_tag="YKL194C"
                     /product="threonine--tRNA ligase MST1"
                     /transcript_id="NM_001179760.1"
                     /db_xref="GI:296146192"
                     /db_xref="GeneID:853640"
     CDS             complement(77258..78646)
                     /gene="MST1"
                     /locus_tag="YKL194C"
                     /EC_number="6.1.1.3"
                     /note="Mitochondrial threonyl-tRNA synthetase;
                     aminoacylates both the canonical threonine tRNA tT(UGU)Q1
                     and the unusual threonine tRNA tT(UAG)Q2 in vitro; lacks a
                     typical editing domain, but has pre-transfer editing
                     activity stimulated by the unusual tRNA-Thr"
                     /codon_start=1
                     /product="threonine--tRNA ligase MST1"
                     /protein_id="NP_012727.1"
                     /db_xref="GI:6322654"
                     /db_xref="SGD:S000001677"
                     /db_xref="GeneID:853640"
                     /translation="MKIQLVRWHCSRNALWNRAFYSTRKATKNASSATPATMTSMVSQ
                     RQDLFMTDPLSPGSMFFLPNGAKIFNKLIEFMKLQQKFKFGFNEVVTPLIYKKTLWEK
                     SGHWENYADDMFKVETTDEEKEEYGLKPMNCPGHCLIFGKKDRSYNELPLRFSDFSPL
                     HRNEASGALSGLTRLRKFHQDDGHIFCTPSQVKSEIFNSLKLIDIVYNKIFPFVKGGS
                     GAESNYFINFSTRPDHFIGDLKVWNHAEQVLKEILEESGKPWKLNPGDGAFYGPKLDI
                     MVTDHLRKTHQVATIQLDFQLPERFDLKFKDQDNSYKRPIMIHRATFGSIERFMALLI
                     DSNEGRWPFWLNPYQAVIIPVNTKNVQQLDMCTALQKKLRNELEADDMEPVPLNDWHF
                     NVDLDIRNEPVGYRIKSAILKNYSYLIIVGDEEVQLQKYNIRERDNRKSFEKLTMSQI
                     WEKFIELEKNYK"
     gene            complement(<78866..>79882)
                     /gene="SDS22"
                     /locus_tag="YKL193C"
                     /gene_synonym="EGP1"
                     /db_xref="GeneID:853641"
     mRNA            complement(<78866..>79882)
                     /gene="SDS22"
                     /locus_tag="YKL193C"
                     /gene_synonym="EGP1"
                     /product="Sds22p"
                     /transcript_id="NM_001179759.1"
                     /db_xref="GI:296146193"
                     /db_xref="GeneID:853641"
     CDS             complement(78866..79882)
                     /gene="SDS22"
                     /locus_tag="YKL193C"
                     /gene_synonym="EGP1"
                     /note="Regulatory subunit of the type 1 protein
                     phosphatase (PP1) Glc7p; whether it functions as a
                     positive or negative regulator of Glc7p is controversial;
                     involved in the regulation of Glc7p nuclear localization
                     and function"
                     /codon_start=1
                     /product="Sds22p"
                     /protein_id="NP_012728.1"
                     /db_xref="GI:6322655"
                     /db_xref="SGD:S000001676"
                     /db_xref="GeneID:853641"
                     /translation="MDKNSVNKDSEEKDERHKIEVVDDTNPDFITADSELTQDLPDDV
                     EVIDLVHLKIKSLEDLNLYRFKNLKQLCLRQNLIESISEVEVLPHDKIVDLDFYDNKI
                     KHISSNVNKLTKLTSLDLSFNKIKHIKNLENLTDLENLYFVQNSISKIENLSTLKSLK
                     NLELGGNKVHSIEPDSFEGLSNLEEIWLGKNSIPRLINLHPLKNLKILSIQSNKLKKI
                     ENLEELTNLEELYLSHNFITKIEGLEKNLKLTTLDVTSNKITSLENLNHLSNLTDIWA
                     SFNKIDQSFESLGENLSALSRLETIYLEGNPIQLENKTSYRRKLTMNLPPSLQKIDAT
                     YIRG"
     gene            complement(<80160..>80537)
                     /gene="ACP1"
                     /locus_tag="YKL192C"
                     /db_xref="GeneID:853642"
     mRNA            complement(<80160..>80537)
                     /gene="ACP1"
                     /locus_tag="YKL192C"
                     /product="Acp1p"
                     /transcript_id="NM_001179758.1"
                     /db_xref="GI:296146194"
                     /db_xref="GeneID:853642"
     CDS             complement(80160..80537)
                     /gene="ACP1"
                     /locus_tag="YKL192C"
                     /note="Mitochondrial matrix acyl carrier protein; involved
                     in biosynthesis of octanoate, which is a precursor to
                     lipoic acid; activated by phosphopantetheinylation
                     catalyzed by Ppt2p"
                     /codon_start=1
                     /product="Acp1p"
                     /protein_id="NP_012729.1"
                     /db_xref="GI:6322656"
                     /db_xref="SGD:S000001675"
                     /db_xref="GeneID:853642"
                     /translation="MFRSVCRISSRVAPSAYRTIMGRSVMSNTILAQRFYSANLSKDQ
                     VSQRVIDVIKAFDKNSPNIANKQISSDTQFHKDLGLDSLDTVELLVAIEEEFDIEIPD
                     KVADELRSVGETVDYIASNPDAN"
     gene            <81035..>82639
                     /gene="DPH2"
                     /locus_tag="YKL191W"
                     /db_xref="GeneID:853643"
     mRNA            <81035..>82639
                     /gene="DPH2"
                     /locus_tag="YKL191W"
                     /product="Dph2p"
                     /transcript_id="NM_001179757.1"
                     /db_xref="GI:296146195"
                     /db_xref="GeneID:853643"
     CDS             81035..82639
                     /gene="DPH2"
                     /locus_tag="YKL191W"
                     /note="Protein required for synthesis of diphthamide;
                     required along with Dph1p, Kti11p, Jjj3p, and Dph5p;
                     diphthamide is a modified histidine residue of translation
                     elongation factor 2 (Eft1p or Eft2p); may act in a complex
                     with Dph1p and Kti11p"
                     /codon_start=1
                     /product="Dph2p"
                     /protein_id="NP_012730.1"
                     /db_xref="GI:6322657"
                     /db_xref="SGD:S000001674"
                     /db_xref="GeneID:853643"
                     /translation="MEVAPALSTTQSDVAFQKVETHEIDRSSYLGPCYNSDELMQLIS
                     AYYNVEPLVGYLEQHPEYQNVTLQFPDDLIKDSSLIVRLLQSKFPHGKIKFWVLADTA
                     YSACCVDEVAAEHVHAEVVVHFGDACLNAIQNLPVVYSFGTPFLDLALVVENFQRAFP
                     DLSSKICLMANAPFSKHLSQLYNILKGDLHYTNIIYSQVNTSAVEEKFVTILDTFHVP
                     EDVDQVGVFEKNSVLFGQHDKADNISPEDYHLFHLTTPQDPRLLYLSTVFQSVHIFDP
                     ALPGMVTGPFPSLMRRYKYMHVARTAGCIGILVNTLSLRNTRETINELVKLIKTREKK
                     HYLFVVGKPNVAKLANFEDIDIWCILGCSQSGIIVDQFNEFYKPIITPYELNLALSEE
                     VTWTGKWVVDFRDAIDEIEQNLGGQDTISASTTSDEPEFDVVRGRYTSTSRPLRALTH
                     LELEAADDDDSKQLTTRHTASGAVIKGTVSTSASALQNRSWKGLGSDFDSTEVDNTGA
                     DIEEGISGVARGYGFDREDAMKKENK"
     gene            <82947..>83550
                     /gene="CNB1"
                     /locus_tag="YKL190W"
                     /gene_synonym="CRV1; YCN2"
                     /db_xref="GeneID:853644"
     mRNA            join(<82947..82998,83075..>83550)
                     /gene="CNB1"
                     /locus_tag="YKL190W"
                     /gene_synonym="CRV1; YCN2"
                     /product="calcineurin regulatory subunit B"
                     /transcript_id="NM_001179756.1"
                     /db_xref="GI:296146196"
                     /db_xref="GeneID:853644"
     CDS             join(82947..82998,83075..83550)
                     /gene="CNB1"
                     /locus_tag="YKL190W"
                     /gene_synonym="CRV1; YCN2"
                     /note="Calcineurin B; regulatory subunit of calcineurin, a
                     Ca++/calmodulin-regulated type 2B protein phosphatase
                     which regulates Crz1p (stress-response transcription
                     factor); other calcineurin subunit encoded by CNA1 and/or
                     CMP1; regulates function of Aly1p alpha-arrestin;
                     myristoylation by Nmt1p reduces calcineurin activity in
                     response to submaximal Ca signals, is needed to prevent
                     constitutive phosphatase activity; protein abundance
                     increases in response to DNA replication stress"
                     /codon_start=1
                     /product="calcineurin regulatory subunit B"
                     /protein_id="NP_012731.1"
                     /db_xref="GI:6322658"
                     /db_xref="SGD:S000001673"
                     /db_xref="GeneID:853644"
                     /translation="MGAAPSKIVDGLLEDTNFDRDEIERLRKRFMKLDRDSSGSIDKN
                     EFMSIPGVSSNPLAGRIMEVFDADNSGDVDFQEFITGLSIFSGRGSKDEKLRFAFKIY
                     DIDKDGFISNGELFIVLKIMVGSNLDDEQLQQIVDRTIVENDSDGDGRLSFEEFKNAI
                     ETTEVAKSLTLQYDV"
     LTR             complement(83808..84115)
                     /note="Ty1 LTR"
                     /db_xref="SGD:S000007050"
     gene            84208..84291
                     /locus_tag="tL(UAA)K"
                     /db_xref="GeneID:853645"
     tRNA            84208..84291
                     /locus_tag="tL(UAA)K"
                     /product="tRNA-Leu"
                     /note="Leucine tRNA (tRNA-Leu), predicted by tRNAscan-SE
                     analysis"
                     /db_xref="SGD:S000006651"
                     /db_xref="GeneID:853645"
     gene            <84704..>85903
                     /gene="HYM1"
                     /locus_tag="YKL189W"
                     /db_xref="GeneID:853646"
     mRNA            <84704..>85903
                     /gene="HYM1"
                     /locus_tag="YKL189W"
                     /product="Hym1p"
                     /transcript_id="NM_001179755.1"
                     /db_xref="GI:296146197"
                     /db_xref="GeneID:853646"
     CDS             84704..85903
                     /gene="HYM1"
                     /locus_tag="YKL189W"
                     /note="Component of the RAM signaling network; is involved
                     in regulation of Ace2p activity and cellular
                     morphogenesis, interacts with Kic1p and Sog2p, localizes
                     to sites of polarized growth during budding and during the
                     mating response"
                     /codon_start=1
                     /product="Hym1p"
                     /protein_id="NP_012732.1"
                     /db_xref="GI:6322659"
                     /db_xref="SGD:S000001672"
                     /db_xref="GeneID:853646"
                     /translation="MFKKYKNQDLDMAFWWKKNPKTPSDYARLIIEQLNKFSSPSLTQ
                     DNKRKVQEECTKYLIGTKHFIVGDTDPHPTPEAIDELYTAMHRADVFYELLLHFVDLE
                     FEARRECMLIFSICLGYSKDNKFVTVDYLVSQPKTISLMLRTAEVALQQKGCQDIFLT
                     VGNMIIECIKYEQLCRIILKDPQLWKFFEFAKLGNFEISTESLQILSAAFTAHPKLVS
                     KEFFSNEINIIRFIKCINKLMAHGSYVTKRQSTKLLASLIVIRSNNALMNIYINSPEN
                     LKLIMTLMTDKSKNLQLEAFNVFKVMVANPRKSKPVFDILVKNRDKLLTYFKTFGLDS
                     QDSTFLDEREFIVQEIDSLPRIISSTTEVSNNNASSSNVASITSPSSVMNNQSSILTH
                     STSPDSR"
     gene            complement(<86225..>88786)
                     /gene="PXA2"
                     /locus_tag="YKL188C"
                     /gene_synonym="PAT1"
                     /db_xref="GeneID:853647"
     mRNA            complement(<86225..>88786)
                     /gene="PXA2"
                     /locus_tag="YKL188C"
                     /gene_synonym="PAT1"
                     /product="ATP-binding cassette long-chain fatty acid
                     transporter PXA2"
                     /transcript_id="NM_001179754.1"
                     /db_xref="GI:296146198"
                     /db_xref="GeneID:853647"
     CDS             complement(86225..88786)
                     /gene="PXA2"
                     /locus_tag="YKL188C"
                     /gene_synonym="PAT1"
                     /note="Subunit of a heterodimeric peroxisomal ABC
                     transport complex; required for import of long-chain fatty
                     acids into peroxisomes; similarity to human
                     adrenoleukodystrophy transporter ABCD1 and ABCD2 and
                     ALD-related proteins; mutations in ABCD1 cause X-linked
                     adrenoleukodystrophy (X-ALD), a peroxisomal disorder;
                     complex also includes Pxa1p"
                     /codon_start=1
                     /product="ATP-binding cassette long-chain fatty acid
                     transporter PXA2"
                     /protein_id="NP_012733.1"
                     /db_xref="GI:6322660"
                     /db_xref="SGD:S000001671"
                     /db_xref="GeneID:853647"
                     /translation="MISTASAFYQKHRVNLLRSSYIILLLATLYNSNSSSSNNKTDKK
                     DSESTVLENKKIEEGKETAVDREEDESSKEELTIVSKHSTDSEDGAIIIDKESKTNHK
                     GGERKGKVDFLFKLLLHDKKCLILFITQAILLNIRTLLSLRVATLDGQLVSTLVRAQY
                     ANFTKILLGKWMILGIPASFINSLISYTTKLCAVTINRKVSDFLLSKYLSNHHTFYSV
                     ASAESVSEIQDNLTKDIYTFSMNSSLLLNQLLKPMLDLILCSFKLLTSNTSVMGEGTL
                     ALGLIVYASNSLLKLIQPNFTRLTMASASLESWFRSLHSNLHSSNEEIALLRGQKREL
                     ENVDYSFYRLVLFLNREIKARAIYDVATAFVIKYTWGAAGLVLCSIPIFFKNKPSEDT
                     LQLKEPGNDMTADFITNRRLLVTASSSIGRFVELKRNIQQLRGIRLRLNKFNDLLDAN
                     KGDDEKEPRDERCIVEYDDSRIKFENIPLITPANQVLVPELSFDLKHGNHLLIIGPNG
                     CGKSSLFRILGGLWPIRATPNKNHQSKLIMPRRTVDRDCAIFYLPQRPYMGNRSTFRE
                     QIIYPDSIEQFKERYHNDYDLGDADLIKILQLLDLEDLVTENMSLLLAQRTSKNDSQQ
                     LSTEDNQSPCAIKVRDAFSIVRNWSEELTIGVQQRLAMARMYYHKPKFAVLDECTSAV
                     APEMEQRMYENAQNFGISLISVCHRTSLWHFHNYLLKFDGKGGYQFGPFNPKERLCNE
                     EKLLELNAILDQQVPLWERKLKDLTIAKESNIIRKSETNLNLFEKIEDPKTSKSNALF
                     NANKGQRITSPTGQETSKRLPLFSQPSSSASSNLLRNNKSLNKKVKTKKEEGKER"
     rep_origin      88789..89287
                     /note="ARS1104;
                     Putative replication origin; identified in multiple array
                     studies, not yet confirmed by plasmid-based assay"
                     /db_xref="SGD:S000130138"
     gene            complement(<89284..>91536)
                     /gene="FAT3"
                     /locus_tag="YKL187C"
                     /db_xref="GeneID:853648"
     mRNA            complement(<89284..>91536)
                     /gene="FAT3"
                     /locus_tag="YKL187C"
                     /product="Fat3p"
                     /transcript_id="NM_001179753.1"
                     /db_xref="GI:296146199"
                     /db_xref="GeneID:853648"
     CDS             complement(89284..91536)
                     /gene="FAT3"
                     /locus_tag="YKL187C"
                     /note="Protein required for fatty acid uptake; protein
                     abundance increases in cortical patches in response to
                     oleate exposure; the authentic, non-tagged protein is
                     detected in a phosphorylated state in highly purified
                     mitochondria in high-throughput studies; FAT3 has a
                     paralog, YLR413W, that arose from the whole genome
                     duplication"
                     /codon_start=1
                     /product="Fat3p"
                     /protein_id="NP_012734.1"
                     /db_xref="GI:6322661"
                     /db_xref="SGD:S000001670"
                     /db_xref="GeneID:853648"
                     /translation="MRIEKHRTPLSKGIIWTILSVCLLFMFTTLILVIVATAGSTANY
                     KPLTNIYIGEADIKHINVSKVIPQIGPILTILGSALTAPNSSLDDIFGAMKNIADTPA
                     LTPLLTLLSNADNTTVTIESLTELAPLAISGNPASSTRQLTEINGLLKYSDNATETLD
                     GLSRLVSASLSSASSNSSSDSTTLVLDLLKDSDNPQNSTDALLTLNNLTMSEKAQLLP
                     VFRLFAFSTNQTATMTALATLMNTTISSSLAQTLLTQLQNTISNGGSLNNTFSTLQPL
                     VPQASAPAFDAVELLLNQTTSTNQTLSTLSDLLEQNLTQSSSAKKAFAALTQLMENSD
                     NSTMVVTSVQSLAAVTNTTQSTQQLIGLDDVISSSSNTNETLSILSELQSGLSGNSSS
                     VQYIPYLFSLLGASTDPKTTFSSLVTLTSWAQENPQTFLPILDILADAKSVQPISAEE
                     LNAMTPNILEYLKIPIYYRLSIFTLCHANLENKILDCNSPHAVQNLDFRSIIYDALVT
                     SDFQPYLNALNISANDLYLEGKLLHREHQYVPAVRSVLALNLLAIIFSFFTMIFIILL
                     YFNRYMFKQPLWLIALALHVCVGVATVLAAIIISVMIAIIKSGTADDKYGVVFKAGPA
                     YTGLIWTAFALSFIATGLIIYTWWRNRRSGRYMSGSVTNRKGEIYTYGDGSAISADRF
                     GDHNLGDDDDADFEKQVNRNEITAIDNSSSANNTDVTGSTSNRTELSHPDVTPKDSNG
                     PVNNNAHLVA"
     gene            complement(<92744..>93298)
                     /gene="MTR2"
                     /locus_tag="YKL186C"
                     /db_xref="GeneID:853649"
     mRNA            complement(<92744..>93298)
                     /gene="MTR2"
                     /locus_tag="YKL186C"
                     /product="Mtr2p"
                     /transcript_id="NM_001179752.1"
                     /db_xref="GI:296146200"
                     /db_xref="GeneID:853649"
     CDS             complement(92744..93298)
                     /gene="MTR2"
                     /locus_tag="YKL186C"
                     /note="mRNA transport regulator; essential nuclear
                     protein; Mex67p and Mtr2p form a mRNA export complex which
                     binds to RNA"
                     /codon_start=1
                     /product="Mtr2p"
                     /protein_id="NP_012735.1"
                     /db_xref="GI:6322662"
                     /db_xref="SGD:S000001669"
                     /db_xref="GeneID:853649"
                     /translation="MNTNSNTMVMNDANQAQITATFTKKILAHLDDPDSNKLAQFVQL
                     FNPNNCRIIFNATPFAQATVFLQMWQNQVVQTQHALTGVDYHAIPGSGTLICNVNCKV
                     RFDESGRDKMGQDATVPIQPNNTGNRNRPNDMNKPRPLWGPYFGISLQLIIDDRIFRN
                     DFNGVISGFNYNMVYKPEDSLLKI"
     gene            <94499..>96265
                     /gene="ASH1"
                     /locus_tag="YKL185W"
                     /db_xref="GeneID:853650"
     mRNA            <94499..>96265
                     /gene="ASH1"
                     /locus_tag="YKL185W"
                     /product="DNA-binding transcription repressor ASH1"
                     /transcript_id="NM_001179751.1"
                     /db_xref="GI:296146201"
                     /db_xref="GeneID:853650"
     CDS             94499..96265
                     /gene="ASH1"
                     /locus_tag="YKL185W"
                     /note="Component of the Rpd3L histone deacetylase complex;
                     zinc-finger inhibitor of HO transcription; mRNA is
                     localized and translated in the distal tip of anaphase
                     cells, resulting in accumulation of Ash1p in daughter cell
                     nuclei and inhibition of HO expression; potential Cdc28p
                     substrate"
                     /codon_start=1
                     /product="DNA-binding transcription repressor ASH1"
                     /protein_id="NP_012736.1"
                     /db_xref="GI:6322663"
                     /db_xref="SGD:S000001668"
                     /db_xref="GeneID:853650"
                     /translation="MSSLYIKTPLHALSAGPDSHANSSYYDNLLLPSFSNLSSNISRN
                     NITTDNNINSASPRKYSFHSLNVSPILSPISLANEILGKKSNTAPASPHHMDYNPISS
                     LTPGNSPEFNKASLSQISFTNPLNYGSGLGFSSNSQPRLPLLDRLSSVSLSKRPERPQ
                     QSLPSLRHLQLLPSPLLQENAARFPDTSKRTSNWKTDLTHWCKDTNYQDYVKIREEVA
                     HFKPLSIPNLTNNQNNDSFNYGKELESTRSSKFHSPSKESFDRTKLIPSILEAKDQFK
                     DLSNNAWSITPPVTPPMSPPTNRTMERTTLRGVEASFFEGKSSNNDSIFNPIISEKLV
                     QEVKHQRQLRGNSFPMPNASHKKTNSFKALQIKKLLANRDILSNNSKSNVRKPSKNKI
                     SKQASNVFGNTARQLVMKLDNASYSSVSASSSPSPSTPTKSGKMRSRSSSPVRPKAYT
                     PSPRSPNYHRFALDSPPQSPRRSSNSSITKKGSRRSSGSSPTRHTTRVCVSCHSSDSP
                     CWRPSWSPRKQDQLCNSCGLRYKKTHTRCLNDLCRKIPTKGEINIMKSNGIDKEFVPE
                     RNCEIEGYRCLFCNYITETVEN"
     gene            <96757..>98157
                     /gene="SPE1"
                     /locus_tag="YKL184W"
                     /gene_synonym="ORD1; SPE10"
                     /db_xref="GeneID:853651"
     mRNA            <96757..>98157
                     /gene="SPE1"
                     /locus_tag="YKL184W"
                     /gene_synonym="ORD1; SPE10"
                     /product="ornithine decarboxylase SPE1"
                     /transcript_id="NM_001179750.1"
                     /db_xref="GI:296146202"
                     /db_xref="GeneID:853651"
     CDS             96757..98157
                     /gene="SPE1"
                     /locus_tag="YKL184W"
                     /gene_synonym="ORD1; SPE10"
                     /EC_number="4.1.1.17"
                     /note="Ornithine decarboxylase; catalyzes the first step
                     in polyamine biosynthesis; degraded in a
                     proteasome-dependent manner in the presence of excess
                     polyamines; deletion decreases lifespan, and increases
                     necrotic cell death and ROS generation"
                     /codon_start=1
                     /product="ornithine decarboxylase SPE1"
                     /protein_id="NP_012737.1"
                     /db_xref="GI:6322664"
                     /db_xref="SGD:S000001667"
                     /db_xref="GeneID:853651"
                     /translation="MSSTQVGNALSSSTTTLVDLSNSTVTQKKQYYKDGETLHNLLLE
                     LKNNQDLELLPHEQAHPKIFQALKARIGRINNETCDPGEENSFFICDLGEVKRLFNNW
                     VKELPRIKPFYAVKCNPDTKVLSLLAELGVNFDCASKVEIDRVLSMNISPDRIVYANP
                     CKVASFIRYAASKNVMKSTFDNVEELHKIKKFHPESQLLLRIATDDSTAQCRLSTKYG
                     CEMENVDVLLKAIKELGLNLAGVSFHVGSGASDFTSLYKAVRDARTVFDKAANEYGLP
                     PLKILDVGGGFQFESFKESTAVLRLALEEFFPVGCGVDIIAEPGRYFVATAFTLASHV
                     IAKRKLSENEAMIYTNDGVYGNMNCILFDHQEPHPRTLYHNLEFHYDDFESTTAVLDS
                     INKTRSEYPYKVSIWGPTCDGLDCIAKEYYMKHDVIVGDWFYFPALGAYTSSAATQFN
                     GFEQTADIVYIDSELD"
     rep_origin      98364..98523
                     /note="ARS1125;
                     Autonomously Replicating Sequence"
                     /db_xref="SGD:S000119035"
     gene            complement(<98395..>98607)
                     /locus_tag="YKL183C-A"
                     /db_xref="GeneID:1500485"
     mRNA            complement(<98395..>98607)
                     /locus_tag="YKL183C-A"
                     /product="hypothetical protein"
                     /transcript_id="NM_001184557.1"
                     /db_xref="GI:296146203"
                     /db_xref="GeneID:1500485"
     CDS             complement(98395..98607)
                     /locus_tag="YKL183C-A"
                     /note="hypothetical protein; identified by fungal homology
                     and RT-PCR"
                     /codon_start=1
                     /product="hypothetical protein"
                     /protein_id="NP_878109.1"
                     /db_xref="GI:33578046"
                     /db_xref="SGD:S000028558"
                     /db_xref="GeneID:1500485"
                     /translation="MYSKILLYRSNVLFMNFFSVFVCTIGTLFLVFADVYVLASAFFQ
                     SKKEKETKFKHLHYQKRSCFFLANIH"
     gene            <98721..>99641
                     /gene="LOT5"
                     /locus_tag="YKL183W"
                     /db_xref="GeneID:853652"
     mRNA            <98721..>99641
                     /gene="LOT5"
                     /locus_tag="YKL183W"
                     /product="Lot5p"
                     /transcript_id="NM_001179749.1"
                     /db_xref="GI:296146204"
                     /db_xref="GeneID:853652"
     CDS             98721..99641
                     /gene="LOT5"
                     /locus_tag="YKL183W"
                     /note="hypothetical protein; gene expression increases in
                     cultures shifted to a lower temperature; protein abundance
                     increases in response to DNA replication stress"
                     /codon_start=1
                     /product="Lot5p"
                     /protein_id="NP_012738.1"
                     /db_xref="GI:6322665"
                     /db_xref="SGD:S000001666"
                     /db_xref="GeneID:853652"
                     /translation="MMKKKPKCQIARTKPSVENVIPYNQFKKTQPRFNGNFSALNNEE
                     YIILFGGGRDLILGSLTPCSSSHLSNQANPQDTSEYGTDLFILNSCIIIWFNGLGYGL
                     EIPYSSVLYHASRRLPDGREGLQLEILLTLERDEVLDMLYQSLAPQACEFDGEEAHAF
                     TVRSVELTIRPKYSIYDRHYNNEIETLFTFENFGVNRGDDLVNNCNEALAVCMDLHGE
                     DVQDQDQEQYQDPSMAFEGAQDLNATYSGLGDTLHGPPVYQNDGLADDLDGDLVMDNV
                     VSRGGPEASMSMEFYANQNLAGRKNSRDNE"
     gene            <100671..>106826
                     /gene="FAS1"
                     /locus_tag="YKL182W"
                     /db_xref="GeneID:853653"
     mRNA            <100671..>106826
                     /gene="FAS1"
                     /locus_tag="YKL182W"
                     /product="tetrafunctional fatty acid synthase subunit
                     FAS1"
                     /transcript_id="NM_001179748.1"
                     /db_xref="GI:296146205"
                     /db_xref="GeneID:853653"
     CDS             100671..106826
                     /gene="FAS1"
                     /locus_tag="YKL182W"
                     /EC_number="4.2.1.59"
                     /EC_number="3.1.2.14"
                     /EC_number="2.3.1.86"
                     /EC_number="2.3.1.39"
                     /EC_number="2.3.1.38"
                     /EC_number="1.3.1.9"
                     /note="Beta subunit of fatty acid synthetase; complex
                     catalyzes the synthesis of long-chain saturated fatty
                     acids; contains acetyltransacylase, dehydratase, enoyl
                     reductase, malonyl transacylase, and palmitoyl
                     transacylase activities"
                     /codon_start=1
                     /product="tetrafunctional fatty acid synthase subunit
                     FAS1"
                     /protein_id="NP_012739.1"
                     /db_xref="GI:6322666"
                     /db_xref="SGD:S000001665"
                     /db_xref="GeneID:853653"
                     /translation="MDAYSTRPLTLSHGSLEHVLLVPTASFFIASQLQEQFNKILPEP
                     TEGFAADDEPTTPAELVGKFLGYVSSLVEPSKVGQFDQVLNLCLTEFENCYLEGNDIH
                     ALAAKLLQENDTTLVKTKELIKNYITARIMAKRPFDKKSNSALFRAVGEGNAQLVAIF
                     GGQGNTDDYFEELRDLYQTYHVLVGDLIKFSAETLSELIRTTLDAEKVFTQGLNILEW
                     LENPSNTPDKDYLLSIPISCPLIGVIQLAHYVVTAKLLGFTPGELRSYLKGATGHSQG
                     LVTAVAIAETDSWESFFVSVRKAITVLFFIGVRCYEAYPNTSLPPSILEDSLENNEGV
                     PSPMLSISNLTQEQVQDYVNKTNSHLPAGKQVEISLVNGAKNLVVSGPPQSLYGLNLT
                     LRKAKAPSGLDQSRIPFSERKLKFSNRFLPVASPFHSHLLVPASDLINKDLVKNNVSF
                     NAKDIQIPVYDTFDGSDLRVLSGSISERIVDCIIRLPVKWETTTQFKATHILDFGPGG
                     ASGLGVLTHRNKDGTGVRVIVAGTLDINPDDDYGFKQEIFDVTSNGLKKNPNWLEEYH
                     PKLIKNKSGKIFVETKFSKLIGRPPLLVPGMTPCTVSPDFVAATTNAGYTIELAGGGY
                     FSAAGMTAAIDSVVSQIEKGSTFGINLIYVNPFMLQWGIPLIKELRSKGYPIQFLTIG
                     AGVPSLEVASEYIETLGLKYLGLKPGSIDAISQVINIAKAHPNFPIALQWTGGRGGGH
                     HSFEDAHTPMLQMYSKIRRHPNIMLIFGSGFGSADDTYPYLTGEWSTKFDYPPMPFDG
                     FLFGSRVMIAKEVKTSPDAKKCIAACTGVPDDKWEQTYKKPTGGIVTVRSEMGEPIHK
                     IATRGVMLWKEFDETIFNLPKNKLVPTLEAKRDYIISRLNADFQKPWFATVNGQARDL
                     ATMTYEEVAKRLVELMFIRSTNSWFDVTWRTFTGDFLRRVEERFTKSKTLSLIQSYSL
                     LDKPDEAIEKVFNAYPAAREQFLNAQDIDHFLSMCQNPMQKPVPFVPVLDRRFEIFFK
                     KDSLWQSEHLEAVVDQDVQRTCILHGPVAAQFTKVIDEPIKSIMDGIHDGHIKKLLHQ
                     YYGDDESKIPAVEYFGGESPVDVQSQVDSSSVSEDSAVFKATSSTDEESWFKALAGSE
                     INWRHASFLCSFITQDKMFVSNPIRKVFKPSQGMVVEISNGNTSSKTVVTLSEPVQGE
                     LKPTVILKLLKENIIQMEMIENRTMDGKPVSLPLLYNFNPDNGFAPISEVMEDRNQRI
                     KEMYWKLWIDEPFNLDFDPRDVIKGKDFEITAKEVYDFTHAVGNNCEDFVSRPDRTML
                     APMDFAIVVGWRAIIKAIFPNTVDGDLLKLVHLSNGYKMIPGAKPLQVGDVVSTTAVI
                     ESVVNQPTGKIVDVVGTLSRNGKPVMEVTSSFFYRGNYTDFENTFQKTVEPVYQMHIK
                     TSKDIAVLRSKEWFQLDDEDFDLLNKTLTFETETEVTFKNANIFSSVKCFGPIKVELP
                     TKETVEIGIVDYEAGASHGNPVVDFLKRNGSTLEQKVNLENPIPIAVLDSYTPSTNEP
                     YARVSGDLNPIHVSRHFASYANLPGTITHGMFSSASVRALIENWAADSVSSRVRGYTC
                     QFVDMVLPNTALKTSIQHVGMINGRKLIKFETRNEDDVVVLTGEAEIEQPVTTFVFTG
                     QGSQEQGMGMDLYKTSKAAQDVWNRADNHFKDTYGFSILDIVINNPVNLTIHFGGEKG
                     KRIRENYSAMIFETIVDGKLKTEKIFKEINEHSTSYTFRSEKGLLSATQFTQPALTLM
                     EKAAFEDLKSKGLIPADATFAGHSLGEYAALASLADVMSIESLVEVVFYRGMTMQVAV
                     PRDELGRSNYGMIAINPGRVAASFSQEALQYVVERVGKRTGWLVEIVNYNVENQQYVA
                     AGDLRALDTVTNVLNFIKLQKIDIIELQKSLSLEEVEGHLFEIIDEASKKSAVKPRPL
                     KLERGFACIPLVGISVPFHSTYLMNGVKPFKSFLKKNIIKENVKVARLAGKYIPNLTA
                     KPFQVTKEYFQDVYDLTGSEPIKEIIDNWEKYEQS"
     gene            <107316..>108599
                     /gene="PRS1"
                     /locus_tag="YKL181W"
                     /gene_synonym="PRP1"
                     /db_xref="GeneID:853654"
     mRNA            <107316..>108599
                     /gene="PRS1"
                     /locus_tag="YKL181W"
                     /gene_synonym="PRP1"
                     /product="ribose phosphate diphosphokinase subunit PRS1"
                     /transcript_id="NM_001179747.1"
                     /db_xref="GI:296146206"
                     /db_xref="GeneID:853654"
     CDS             107316..108599
                     /gene="PRS1"
                     /locus_tag="YKL181W"
                     /gene_synonym="PRP1"
                     /EC_number="2.7.6.1"
                     /note="5-phospho-ribosyl-1(alpha)-pyrophosphate
                     synthetase; synthesizes PRPP, which is required for
                     nucleotide, histidine, and tryptophan biosynthesis; plays
                     a key role in cell wall integrity (CWI) pathway; one of
                     five related enzymes, which are active as heteromultimeric
                     complexes; missense mutations in human homolog PRPS1 are
                     associated with neuropathic Arts syndrome and
                     Charcot-Marie Tooth (CMTX5) disease"
                     /codon_start=1
                     /product="ribose phosphate diphosphokinase subunit PRS1"
                     /protein_id="NP_012740.1"
                     /db_xref="GI:6322667"
                     /db_xref="SGD:S000001664"
                     /db_xref="GeneID:853654"
                     /translation="MRKCKIFVGNSHPELGNMVCQRLGIEPAPCTLKKFANGETSVQI
                     GVSVRDEDVYVIQSGSPSINDDIMELLILVSACRGGSARKITAVIPQFPYSKQCKMKR
                     HRGAITARMLANLLVMAGADHVVSMDLHASQMQGFFTKPVDNLYGGPSLAKWIRENVE
                     DYEDAVVVSKNPGGTKRVTALADSLKINFAMIHTDRRRSKDLYSQNKDLQQLKLRKQS
                     MLRKNRPIIRQGDHPNEEENIILSNGIQTARIRNGHVIGDDEADDDEDAILESDSELH
                     SIDGLDSHGLGGTYDAVDSEDEEEIPVLYREQLITLVGNVRGRSAIILDDMIDRPGSF
                     ISAAEHLVQNCGAKKVYVVATHGIFTGDCLEELEKSDAIDTIVVTNTYPISGERIAGS
                     KKLVTIDVSPIFAECIRRDHYGESISVLFDSLAAL"
     gene            <109269..>110129
                     /gene="RPL17A"
                     /locus_tag="YKL180W"
                     /gene_synonym="RPL17"
                     /db_xref="GeneID:853674"
     mRNA            join(<109269..109577,109884..>110129)
                     /gene="RPL17A"
                     /locus_tag="YKL180W"
                     /gene_synonym="RPL17"
                     /product="ribosomal 60S subunit protein L17A"
                     /transcript_id="NM_001179746.1"
                     /db_xref="GI:296146207"
                     /db_xref="GeneID:853674"
     CDS             join(109269..109577,109884..110129)
                     /gene="RPL17A"
                     /locus_tag="YKL180W"
                     /gene_synonym="RPL17"
                     /note="Ribosomal 60S subunit protein L17A; copurifies with
                     the Dam1 complex (aka DASH complex); homologous to
                     mammalian ribosomal protein L17 and bacterial L22; RPL17A
                     has a paralog, RPL17B, that arose from the whole genome
                     duplication; protein abundance increases in response to
                     DNA replication stress"
                     /codon_start=1
                     /product="ribosomal 60S subunit protein L17A"
                     /protein_id="NP_012741.1"
                     /db_xref="GI:6322668"
                     /db_xref="SGD:S000001663"
                     /db_xref="GeneID:853674"
                     /translation="MARYGATSTNPAKSASARGSYLRVSFKNTRETAQAINGWELTKA
                     QKYLEQVLDHQRAIPFRRFNSSIGRTAQGKEFGVTKARWPAKSVKFVQGLLQNAAANA
                     EAKGLDATKLYVSHIQVNQAPKQRRRTYRAHGRINKYESSPSHIELVVTEKEEAVAKA
                     AEKKVVRLTSRQRGRIAAQKRIAA"
     gene            complement(<110464..>112503)
                     /gene="COY1"
                     /locus_tag="YKL179C"
                     /db_xref="GeneID:853675"
     mRNA            complement(<110464..>112503)
                     /gene="COY1"
                     /locus_tag="YKL179C"
                     /product="Coy1p"
                     /transcript_id="NM_001179745.1"
                     /db_xref="GI:296146208"
                     /db_xref="GeneID:853675"
     CDS             complement(110464..112503)
                     /gene="COY1"
                     /locus_tag="YKL179C"
                     /note="Golgi membrane protein with similarity to mammalian
                     CASP; genetic interactions with GOS1 (encoding a Golgi
                     snare protein) suggest a role in Golgi function"
                     /codon_start=1
                     /product="Coy1p"
                     /protein_id="NP_012742.1"
                     /db_xref="GI:6322669"
                     /db_xref="SGD:S000001662"
                     /db_xref="GeneID:853675"
                     /translation="MDTSVYSHALDIWAKADLTNLQRELDADVIEIKDKETLSLNSRK
                     SLATETKKFKKLEPEEKLNNVNKIIKQYQREIDNLTQRSKFSEKVLFDVYEKLSEAPD
                     PQPLLQSSLEKLGKIDDSKELKEKISYLEDKLAKYADYETLKSRLLDLEQSSAKTLAK
                     RLTAKTQEINSTWEEKGRNWKEREADLLKQLTNVQEQNKALEAKISKNIDIEGNGNED
                     GDQENNQKEVSTRIAEYNLVTQELETTQARIYQLEKRNEELSGALAKATSEAEKETEL
                     HAKELKLNQLESENALLSASYEQERKSTSHAINELKEQLNSVVAESESYKSELETVRR
                     KLNNYSDYNKIKEELSALKKIEFGVNEDDSDNDIRSEDKNDNTFESSLLSANKKLQAT
                     LAEYRSKSTAQEEERNELKKSVDQLKQQIATLKEANEKLETDLEKVENVSPHFNETAS
                     MMSGVTRQMNNRTSHKMSPTSSIIGIPEDGELSGNQSTILPIVTKQRDRFRSRNMDLE
                     KQLRQGNSEKGKLKLEISKLKGDNTKLYERIRYLQSYNNNNAPVNQSTERIDVESQYS
                     RVYDESLHPMANFRQNELNHYKNKKLSALEKLFSSFAKVILQNKMTRMVFLFYCIGLH
                     GLVFMMSMYVINISGYMTPEVGIVQSAKSSSNLNGGLGGAEKVAAGVGSVHGINR"
     gene            complement(<113215..>114627)
                     /gene="STE3"
                     /locus_tag="YKL178C"
                     /gene_synonym="DAF2"
                     /db_xref="GeneID:853677"
     mRNA            complement(<113215..>114627)
                     /gene="STE3"
                     /locus_tag="YKL178C"
                     /gene_synonym="DAF2"
                     /product="Ste3p"
                     /transcript_id="NM_001179744.1"
                     /db_xref="GI:296146209"
                     /db_xref="GeneID:853677"
     CDS             complement(113215..114627)
                     /gene="STE3"
                     /locus_tag="YKL178C"
                     /gene_synonym="DAF2"
                     /note="Receptor for a factor pheromone; couples to MAP
                     kinase cascade to mediate pheromone response; transcribed
                     in alpha cells and required for mating by alpha cells,
                     ligand bound receptors endocytosed and recycled to the
                     plasma membrane; GPCR"
                     /codon_start=1
                     /product="Ste3p"
                     /protein_id="NP_012743.1"
                     /db_xref="GI:6322671"
                     /db_xref="SGD:S000001661"
                     /db_xref="GeneID:853677"
                     /translation="MSYKSAIIGLCLLAVILLAPPLAWHSHTKNIPAIILITWLLTMN
                     LTCIVDAAIWSDDDFLTRWDGKGWCDIVIKLQVGANIGISCAVTNIIYNLHTILKADS
                     VLPDLSSWTKIVKDLVISLFTPVMVMGFSYLLQVFRYGIARYNGCQNLLSPTWITTVL
                     YTMWMLIWSFVGAVYATLVLFVFYKKRKDVRDILHCTNSGLNLTRFARLLIFCFIIIL
                     VMFPFSVYTFVQDLQQVEGHYTFKNTHSSTIWNTIIKFDPGRPIYNIWLYVLMSYLVF
                     LIFGLGSDALHMYSKFLRSIKLGFVLDMWKRFIDKNKEKRVGILLNKLSSRKESRNPF
                     STDSENYISTCTENYSPCVGTPISQAHFYVDYRIPDDPRKSQNKSKKYLFADKETDDI
                     LDEIDLKESRHIPYVTQGQSFDDEISLGGFSKVTLDYSEKLHNSASSNFEGESLCYSP
                     ASKEENSSSNEHSSENTAGP"
     gene            complement(<115500..>117986)
                     /gene="LST4"
                     /locus_tag="YKL176C"
                     /db_xref="GeneID:853678"
     mRNA            complement(<115500..>117986)
                     /gene="LST4"
                     /locus_tag="YKL176C"
                     /product="Lst4p"
                     /transcript_id="NM_001179742.1"
                     /db_xref="GI:296146210"
                     /db_xref="GeneID:853678"
     CDS             complement(115500..117986)
                     /gene="LST4"
                     /locus_tag="YKL176C"
                     /note="Protein possibly involved in a post-Golgi secretory
                     pathway; required for the transport of nitrogen-regulated
                     amino acid permease Gap1p from the Golgi to the cell
                     surface"
                     /codon_start=1
                     /product="Lst4p"
                     /protein_id="NP_012745.1"
                     /db_xref="GI:6322672"
                     /db_xref="SGD:S000001659"
                     /db_xref="GeneID:853678"
                     /translation="MLGNLLRNKTSSSGFEKSSEHSDFSSVVPNVPVYCKAASTGTTK
                     TAAGALLDTAVNVEKPSEMLSTTSPPILDHISDDLKLKLFGSRDIPYSRPIDTLQNNG
                     GLGTDKITSINEKTYAFRILIIEEAGQMACRNNYRDIFDYTTSKISNSMEQIRPSELK
                     EYIFGSPVRSSDLTQCDKIRTIPNSDLVLITRIFYYTHQYNRIAISLCIPRILLPVVA
                     ESWSSISSWLTQTQKMLIGFLTKNRIMQENTGNYSNNSVIKLSNIDIRTHYPKEIEIM
                     VQTLQKRVIPGLRSMSEIPRLFLYPETFKEFVHVWFKSIFNWIEIKDGPKLGFLPLLM
                     AMIISDYRHTIRELKTSKIVILSGNMVVANKLLFILSALLEPKYKGQITIRRENIRSD
                     SSAVSRNKSNNNFVDKPETELSTLTSTDNLLSRTENNSNHNYNNSNVSSNSIGSPNFH
                     SLRKGWQIPNRRNSNTSVSVSSSESLAEVIQPSSFKSGSSSLHYLSSSISSQPGSYGS
                     WFNKRPTISQFFQPSPSLKHNESWERLQTTAGNMQRTSSSSSLQQATSRLSLTTPQQS
                     PSISEYDEYPWMGTPGSPNVGDVSHAPPLVKNISYKFPLKNVELKRDCQRISQDDLLD
                     EAFERICQPSLADLNSTYEIFPGNSSYADILTTDSDIDDGLMNKPLELLPKYTMYLTH
                     FNNFFQLQACPAGQESESRITNSMKIDLLKADYTRSLLVSLRSRDIRDVALKREFTGN
                     NNNNSNQNIYDENFVGKRKYVLKQKTRKIFSCGKIGKLSTSLENCVNFVENSIKSAMM
                     LYDDNGIDSELRDSEALRIFSSLVHYCNAG"
     gene            <118793..>120304
                     /gene="ZRT3"
                     /locus_tag="YKL175W"
                     /db_xref="GeneID:853679"
     mRNA            <118793..>120304
                     /gene="ZRT3"
                     /locus_tag="YKL175W"
                     /product="Zn(2+) transporter ZRT3"
                     /transcript_id="NM_001179741.1"
                     /db_xref="GI:296146211"
                     /db_xref="GeneID:853679"
     CDS             118793..120304
                     /gene="ZRT3"
                     /locus_tag="YKL175W"
                     /note="Vacuolar membrane zinc transporter; transports zinc
                     from storage in the vacuole to the cytoplasm when needed;
                     transcription is induced under conditions of zinc
                     deficiency"
                     /codon_start=1
                     /product="Zn(2+) transporter ZRT3"
                     /protein_id="NP_012746.1"
                     /db_xref="GI:6322673"
                     /db_xref="SGD:S000001658"
                     /db_xref="GeneID:853679"
                     /translation="MEKIPRWLLFSLISSVLCILGALCVPLLSVAFDSKRNSQSKLVN
                     YGLSLSAGSMITTSLYMLLPRIEKSNRFKVFPGLLLGICLSFFLNYLVHAFASESLVH
                     CADSGDHATGSHIHSKSHSHSHSHSHADSHSNFSNDHDLENAPSEHGYATSSSSVSEN
                     DPLITKDSDRPQMKKKMSLIDLLTRRKSEGECCDLNKCTPLLQSEQPEYIACVPPVIK
                     SSQSERNVPHGCEGSEDNGQSDDKDHRGLVCVENNIGYDLENLSLYRKNFLSSRHHHS
                     SESPENYGSNQLSHSFSSPLGNDVTENPAALADTQYHPENGSLYPHHHHLETPFSKLL
                     SIGMQTCLVLALHKFPEGFIIFYTNRSDSSKSLGFSIFLSLTIHNFVEGFAMTLPFYT
                     VFESKWVAILITAVLGGGSQPLGALIGYFIFKGSTPRDHEPNMDFLLSVTAGFLLVIG
                     LQMFQTGIGFSDGHHHHQGEGDEEMKQSHSSGTTCLKWCCTGVLLILASALFT"
     gene            complement(<120380..>122236)
                     /gene="TPO5"
                     /locus_tag="YKL174C"
                     /db_xref="GeneID:853680"
     mRNA            complement(<120380..>122236)
                     /gene="TPO5"
                     /locus_tag="YKL174C"
                     /product="Tpo5p"
                     /transcript_id="NM_001179740.1"
                     /db_xref="GI:296146212"
                     /db_xref="GeneID:853680"
     CDS             complement(120380..122236)
                     /gene="TPO5"
                     /locus_tag="YKL174C"
                     /note="Protein involved in excretion of putrescine and
                     spermidine; putative polyamine transporter in the Golgi or
                     post-Golgi vesicles"
                     /codon_start=1
                     /product="Tpo5p"
                     /protein_id="NP_012747.1"
                     /db_xref="GI:6322674"
                     /db_xref="SGD:S000001657"
                     /db_xref="GeneID:853680"
                     /translation="MPEYTLLADNIRENIVHFDPNGLFDNLHTIVHEDDSQENEEAEH
                     FNYDQVLDKSLLSRGSIVGLGLGLMSPVLGMCTSMAIGLINGGPLTIMLGFLISGVCI
                     WFSSLSLGEIVSKFPMELHVGSAMLAPEKLKLVCSWYTGWLMLIGNWTMSTSITFAGA
                     QLTISLILMTNSNLISEAHLIFYTVIVFYLVVTVVGLVNLKFARFIETINKVCVYWII
                     YAIIFIDILLLVFHKGKFRSLKYALFHFDNNLSGYKSAFLSFIIGFQQSNFTLQGFSM
                     LPALADEVKVPEKDIPRGMSNAVLLSAFSGVIFLIPIMLILPDNDLLFTNHKVLPIVN
                     IFTKSTDSVVLSFFLVLLILGNLLFSGIGSITTSSRAVYSFSRDQAIPYYDKWTYVEP
                     DSQSKVPKNSVVLSMIISYFLGLLALISTAAFNAFIGAAVLCLCSATFIPLVLVLFTR
                     RRAIRSAPVKIRYKFGWFINIVSIVWLLLSMVSVCLPTQVPVTFKTMNYALMVYVFCI
                     LVITGLYFKWGKYNFRLPLADDIKAPIPSDAEETVFELEDSNVEHTLNSGTTVKESVE
                     NNSEEGFIKVHPKSSTENPFEENEENVITDYGDEHHTAEQEFDLADDRRYDI"
     gene            <122517..>125543
                     /gene="SNU114"
                     /locus_tag="YKL173W"
                     /gene_synonym="GIN10"
                     /db_xref="GeneID:853681"
     mRNA            <122517..>125543
                     /gene="SNU114"
                     /locus_tag="YKL173W"
                     /gene_synonym="GIN10"
                     /product="U5 snRNP GTPase SNU114"
                     /transcript_id="NM_001179739.1"
                     /db_xref="GI:296146213"
                     /db_xref="GeneID:853681"
     CDS             122517..125543
                     /gene="SNU114"
                     /locus_tag="YKL173W"
                     /gene_synonym="GIN10"
                     /note="GTPase component of U5 snRNP involved in mRNA
                     splicing via spliceosome; binds directly to U5 snRNA;
                     proposed to be involved in conformational changes of the
                     spliceosome; similarity to ribosomal translocation factor
                     EF-2"
                     /codon_start=1
                     /product="U5 snRNP GTPase SNU114"
                     /protein_id="NP_012748.1"
                     /db_xref="GI:6322675"
                     /db_xref="SGD:S000001656"
                     /db_xref="GeneID:853681"
                     /translation="MEGDDLFDEFGNLIGVDPFDSDEEESVLDEQEQYQTNTFEGSGN
                     NNEIESRQLTSLGSKKELGISLEHPYGKEVEVLMETKNTQSPQTPLVEPVTERTKLQE
                     HTIFTQLKKNIPKTRYNRDYMLSMANIPERIINVGVIGPLHSGKTSLMDLLVIDSHKR
                     IPDMSKNVELGWKPLRYLDNLKQEIDRGLSIKLNGSTLLCTDLESKSRMINFLDAPGH
                     VNFMDETAVALAASDLVLIVIDVVEGVTFVVEQLIKQSIKNNVAMCFVINKLDRLILD
                     LKLPPMDAYLKLNHIIANINSFTKGNVFSPIDNNIIFASTKLGFTFTIKEFVSYYYAH
                     SIPSSKIDDFTTRLWGSVYYHKGNFRTKPFENVEKYPTFVEFILIPLYKIFSYALSME
                     KDKLKNLLRSNFRVNLSQEALQYDPQPFLKHVLQLIFRQQTGLVDAITRCYQPFELFD
                     NKTAHLSIPGKSTPEGTLWAHVLKTVDYGGAEWSLVRIYSGLLKRGDTVRILDTSQSE
                     SRQKRQLHDISKTETSNEDEDEDDETPSCEVEEIGLLGGRYVYPVHEAHKGQIVLIKG
                     ISSAYIKSATLYSVKSKEDMKQLKFFKPLDYITEAVFKIVLQPLLPRELPKLLDALNK
                     ISKYYPGVIIKVEESGEHVILGNGELYMDCLLYDLRASYAKIEIKISDPLTVFSESCS
                     NESFASIPVSNSISRLGEENLPGLSISVAAEPMDSKMIQDLSRNTLGKGQNCLDIDGI
                     MDNPRKLSKILRTEYGWDSLASRNVWSFYNGNVLINDTLPDEISPELLSKYKEQIIQG
                     FYWAVKEGPLAEEPIYGVQYKLLSISVPSDVNIDVMKSQIIPLMKKACYVGLLTAIPI
                     LLEPIYEVDITVHAPLLPIVEELMKKRRGSRIYKTIKVAGTPLLEVRGQVPVIESAGF
                     ETDLRLSTNGLGMCQLYFWHKIWRKVPGDVLDKDAFIPKLKPAPINSLSRDFVMKTRR
                     RKGISTGGFMSNDGPTLEKYISAELYAQLRENGLVP"
     gene            <125759..>127042
                     /gene="EBP2"
                     /locus_tag="YKL172W"
                     /db_xref="GeneID:853682"
     mRNA            <125759..>127042
                     /gene="EBP2"
                     /locus_tag="YKL172W"
                     /product="Ebp2p"
                     /transcript_id="NM_001179738.1"
                     /db_xref="GI:296146214"
                     /db_xref="GeneID:853682"
     CDS             125759..127042
                     /gene="EBP2"
                     /locus_tag="YKL172W"
                     /note="Required for 25S rRNA maturation and 60S ribosomal
                     subunit assembly; localizes to the nucleolus and in foci
                     along nuclear periphery; constituent of 66S pre-ribosomal
                     particles; cooperates with Rrs1p and Mps3p to mediate
                     telomere clustering by binding Sir4p, but is not involved
                     in telomere tethering"
                     /codon_start=1
                     /product="Ebp2p"
                     /protein_id="NP_012749.1"
                     /db_xref="GI:6322676"
                     /db_xref="SGD:S000001655"
                     /db_xref="GeneID:853682"
                     /translation="MAKGFKLKELLSHQKEIEKAEKLENDLKKKKSQELKKEEPTIVT
                     ASNLKKLEKKEKKADVKKEVAADTEEYQSQALSKKEKRKLKKELKKMQEQDATEAQKH
                     MSGDEDESGDDREEEEEEEEEEEGRLDLEKLAKSDSESEDDSESENDSEEDEDVVAKE
                     ESEEKEEQEEEQDVPLSDVEFDSDADVVPHHKLTVNNTKAMKHALERVQLPWKKHSFQ
                     EHQSVTSETNTDEHIKDIYDDTERELAFYKQSLDAVLVARDELKRLKVPFKRPLDYFA
                     EMVKSDEHMDKIKGKLIEEASDKKAREEARRQRQLKKFGKQVQNATLQKRQLEKRETL
                     EKIKSLKNKRKHNEIDHSEFNVGVEEEVEGKRFDRGRPNGKRAAKNAKYGQGGMKRFK
                     RKNDATSSADVSGFSSRKMKGKTNRPGKSRRARRF"
     gene            <127475..>130261
                     /gene="NNK1"
                     /locus_tag="YKL171W"
                     /db_xref="GeneID:853683"
     mRNA            <127475..>130261
                     /gene="NNK1"
                     /locus_tag="YKL171W"
                     /product="protein kinase NNK1"
                     /transcript_id="NM_001179737.1"
                     /db_xref="GI:296146215"
                     /db_xref="GeneID:853683"
     CDS             127475..130261
                     /gene="NNK1"
                     /locus_tag="YKL171W"
                     /EC_number="2.7.11.1"
                     /note="Protein kinase; implicated in proteasome function;
                     interacts with TORC1, Ure2 and Gdh2; overexpression leads
                     to hypersensitivity to rapamycin and nuclear accumulation
                     of Gln3; epitope-tagged protein localizes to the
                     cytoplasm"
                     /codon_start=1
                     /product="protein kinase NNK1"
                     /protein_id="NP_012750.1"
                     /db_xref="GI:6322677"
                     /db_xref="SGD:S000001654"
                     /db_xref="GeneID:853683"
                     /translation="MFTSQRQLRQNGSPMSSSRSSQHSSGTASPISDSPASNRSYGRD
                     LRGLMGIDIPANEPAFNRANSSDTIYFRPKKIYKMEHEHPSRSTLVQLQTRSQPDDVA
                     SSQVNPEGGTDDLELGDPCGNQSLYTIGAEYVPDLDFTKLVNEWQKSTEDLYEFRSSA
                     TPQVQIKDSGKGNYELWSSPDAILTQNKLRRDSFSQENSDSLSPEDSILSRNLHSKVK
                     PIPLPRNSQQIFTPLSNLEAERRSSYTTSSNNNSITQNNKFSFAKLKYSLPTQSSAVP
                     ASFDSNASSLNFLPTTTLSTLSELQISPNDMMDLIQKLPRNFLNLPYTQRKKVIIEHA
                     PSHDYKAMMSLVKKFMLTSSRSNFSLAGFANNASVSQATANDDNINSRNTPNNSNDTY
                     VNTRPLQRSRHGSIASQFLSSFSPSMTSIAKMNSNPLSGSAGGSARPDDKGMEILGHR
                     LGKIIGFGAWGIIRECFDIETGVGRVIKIVKFKGHQNIKKHVLREVAIWRTLKHNRIL
                     PLLDWKLDDNYAMYCLTERINDGTLYDLVISWDEFKRSKIPFAERCRLTIFLSLQLLS
                     ALKYMHSKTIVHGDIKLENCLLQKEGKKSDWKVFLCDFGMSCHFDEKHVYRNDTFDEN
                     LSSGNSHRKRKSIEQTNLIKYPTTNFLPDDRTNDFDASENLKYQFENRKHQPFTPKGM
                     VSSSSHSLKHLNQPSSSSSSNLFHKPASQPQPQHRSPFHGRHKTTDFSNLEPEPSKYI
                     GSLPYASPELLRYSDARRSKSVEMHIYDSPDSSQSEISAASSSSSNLSSLSSSTKASA
                     VTNSGVTTSSPSGSSTDFPCIVSPLGPASDIWALGVMLYTMLVGKLPFNHEFEPRLRS
                     LIKVGEFDRFSLAQVCKFDRKKNEGTIGQGLYDTVIGCLTIDLDKRWKLKRIEEVLQN
                     EMNLSEAIHDNNGS"
     gene            <130634..>131050
                     /gene="MRPL38"
                     /locus_tag="YKL170W"
                     /db_xref="GeneID:853684"
     mRNA            <130634..>131050
                     /gene="MRPL38"
                     /locus_tag="YKL170W"
                     /product="mitochondrial 54S ribosomal protein YmL38/YmL34"
                     /transcript_id="NM_001179736.1"
                     /db_xref="GI:296146216"
                     /db_xref="GeneID:853684"
     CDS             130634..131050
                     /gene="MRPL38"
                     /locus_tag="YKL170W"
                     /note="Mitochondrial ribosomal protein of the large
                     subunit; appears as two protein spots (YmL34 and YmL38) on
                     two-dimensional SDS gels; protein abundance increases in
                     response to DNA replication stress"
                     /codon_start=1
                     /product="mitochondrial 54S ribosomal protein YmL38/YmL34"
                     /protein_id="NP_012751.1"
                     /db_xref="GI:6322678"
                     /db_xref="SGD:S000001653"
                     /db_xref="GeneID:853684"
                     /translation="MIFLKSVIKVIDNSGAQLAECIKVIRKGSPKSPAMVGDRIVCVI
                     QKAKPLTQNITGTANTNRVKKGDICHAIVVRSKQRNMCRKDGSTVAFGDTACVLINKN
                     TGEPLGTRIMANDGCVDRTLKDKGYNKICSLASRVI"
     gene            complement(<131288..>133462)
                     /gene="KKQ8"
                     /locus_tag="YKL168C"
                     /db_xref="GeneID:853686"
     mRNA            complement(<131288..>133462)
                     /gene="KKQ8"
                     /locus_tag="YKL168C"
                     /product="putative serine/threonine protein kinase KKQ8"
                     /transcript_id="NM_001179734.1"
                     /db_xref="GI:296146217"
                     /db_xref="GeneID:853686"
     CDS             complement(131288..133462)
                     /gene="KKQ8"
                     /locus_tag="YKL168C"
                     /EC_number="2.7.11.1"
                     /note="Putative serine/threonine protein kinase with
                     unknown cellular role; KKQ8 has a paralog, HAL5, that
                     arose from the whole genome duplication"
                     /codon_start=1
                     /product="putative serine/threonine protein kinase KKQ8"
                     /protein_id="NP_012753.2"
                     /db_xref="GI:99030927"
                     /db_xref="SGD:S000001651"
                     /db_xref="GeneID:853686"
                     /translation="MVMQEEKKRQQPVTRRVRSFSESFKNLFRPPRSRDSSPINVTRI
                     PYRSSSTSPKRSSEPPRRSTVSAQILDPKNSPIRQRSYTLKCCTPGLSHPFRQTGSGA
                     SNSPTRHRSISGEEQEIVNSLPEYKRSASHTFHGIRRPRSRSSSVSSCDSSNGTTSSS
                     DSQWAMDSLLDDSDNDLTPYRGSNKDILKSKDRAPYNYIDDYNKKALRRATSYPNPLP
                     SKQFYNERLYTRRSHPDEESLESLPRFAGADVQCIIEQNGFKVYEDGSHEHNIKLSGV
                     IAKLEKGNSLPAHRQGSLSRPRLGITLSGLFKHHKNECDIENALSLLPNVEKSQTNHE
                     KRTGQSPNDSNRSSPTQGREDYLKIVNPDASLGSDELKLINSLSSRIHKSLQNYLQEK
                     NLKPAECIGEQAPTFQDNYGHPVGLVGAGAYGEVKLCARLRNEKDSPPFETYHDSKYI
                     YYAVKELKPKPDSDLEKFCTKITSEFIIGHSLSHYHKNGKKPAPNILNVFDILEDSSS
                     FIEVMEFCPAGDLYGMLVGKSKLKGRLHPLEADCFMKQLLHGVKFMHDHGIAHCDLKP
                     ENILFYPHGLLKICDFGTSSVFQTAWERRVHAQKGIIGSEPYVAPEEFVDGEYYDPRL
                     IDCWSCGVVYITMILGHYLWKVASREKDMSYDEFYKEMQRKNQFRVFEELKHVNSELA
                     TNRKIALYRIFQWEPRKRISVGKLLDMQWMKSTNCCLIYDST"
     gene            complement(<133721..>134134)
                     /gene="MRP49"
                     /locus_tag="YKL167C"
                     /db_xref="GeneID:853687"
     mRNA            complement(<133721..>134134)
                     /gene="MRP49"
                     /locus_tag="YKL167C"
                     /product="mitochondrial 54S ribosomal protein MRP49"
                     /transcript_id="NM_001179733.1"
                     /db_xref="GI:296146218"
                     /db_xref="GeneID:853687"
     CDS             complement(133721..134134)
                     /gene="MRP49"
                     /locus_tag="YKL167C"
                     /note="Mitochondrial ribosomal protein of the large
                     subunit; not essential for mitochondrial translation"
                     /codon_start=1
                     /product="mitochondrial 54S ribosomal protein MRP49"
                     /protein_id="NP_012754.1"
                     /db_xref="GI:6322681"
                     /db_xref="SGD:S000001650"
                     /db_xref="GeneID:853687"
                     /translation="MSKVAQQLKFLNKISATTRLPQILVDPKKYSGLRLTFQTKNHNG
                     HMGARVFWHNYLPTLQFYNPRMKFDVIRIKNEDKQKSVPCKLEILSHEGSVVETIDMR
                     NKMHEDIMKDLLDKIEHVPLPENEIIRVGPQESII"
     gene            complement(<134509..>135705)
                     /gene="TPK3"
                     /locus_tag="YKL166C"
                     /db_xref="GeneID:853688"
     mRNA            complement(<134509..>135705)
                     /gene="TPK3"
                     /locus_tag="YKL166C"
                     /product="cAMP-dependent protein kinase catalytic subunit
                     TPK3"
                     /transcript_id="NM_001179732.1"
                     /db_xref="GI:296146219"
                     /db_xref="GeneID:853688"
     CDS             complement(134509..135705)
                     /gene="TPK3"
                     /locus_tag="YKL166C"
                     /EC_number="2.7.11.11"
                     /note="cAMP-dependent protein kinase catalytic subunit;
                     promotes vegetative growth in response to nutrients via
                     the Ras-cAMP signaling pathway; partially redundant with
                     Tpk1p and Tpk2p; localizes to P-bodies during stationary
                     phase; TPK3 has a paralog, TPK1, that arose from the whole
                     genome duplication"
                     /codon_start=1
                     /product="cAMP-dependent protein kinase catalytic subunit
                     TPK3"
                     /protein_id="NP_012755.1"
                     /db_xref="GI:6322682"
                     /db_xref="SGD:S000001649"
                     /db_xref="GeneID:853688"
                     /translation="MYVDPMNNNEIRKLSITAKTETTPDNVGQDIPVNAHSVHEECSS
                     NTPVEINGRNSGKLKEEASAGICLVKKPMLQYRDTSGKYSLSDFQILRTLGTGSFGRV
                     HLIRSNHNGRFYALKTLKKHTIVKLKQVEHTNDERRMLSIVSHPFIIRMWGTFQDSQQ
                     VFMVMDYIEGGELFSLLRKSQRFPNPVAKFYAAEVCLALEYLHSKDIIYRDLKPENIL
                     LDKNGHIKITDFGFAKYVPDVTYTLCGTPDYIAPEVVSTKPYNKSVDWWSFGVLIYEM
                     LAGYTPFYNSNTMKTYENILNAELKFPPFFHPDAQDLLKKLITRDLSERLGNLQNGSE
                     DVKNHPWFNEVIWEKLLARYIETPYEPPIQQGQGDTSQFDRYPEEEFNYGIQGEDPYM
                     DLMKEF"
     gene            complement(<137932..>140691)
                     /gene="MCD4"
                     /locus_tag="YKL165C"
                     /gene_synonym="FSR2; SSU21; ZRG16"
                     /db_xref="GeneID:853690"
     mRNA            complement(<137932..>140691)
                     /gene="MCD4"
                     /locus_tag="YKL165C"
                     /gene_synonym="FSR2; SSU21; ZRG16"
                     /product="Mcd4p"
                     /transcript_id="NM_001179731.1"
                     /db_xref="GI:296146220"
                     /db_xref="GeneID:853690"
     CDS             complement(137932..140691)
                     /gene="MCD4"
                     /locus_tag="YKL165C"
                     /gene_synonym="FSR2; SSU21; ZRG16"
                     /EC_number="2.-.-.-"
                     /note="Protein involved in GPI anchor synthesis;
                     multimembrane-spanning protein that localizes to the
                     endoplasmic reticulum; highly conserved among eukaryotes;
                     GPI stands for glycosylphosphatidylinositol"
                     /codon_start=1
                     /product="Mcd4p"
                     /protein_id="NP_012756.1"
                     /db_xref="GI:6322683"
                     /db_xref="SGD:S000001648"
                     /db_xref="GeneID:853690"
                     /translation="MWNKTRTTLLAVGVLFHLFYLWSIFDIYFISPLVHGMSPYQSTP
                     TPPAKRLFLIVGDGLRADTTFDKVTHPVSGKTEFLAPFIRSLVMNNATYGISHTRMPT
                     ESRPGHVAMIAGFYEDVSAVTKGWKSNPVNFDSFFNQSTHTYSFGSPDILPMFKDGAS
                     DPNKVDTWMYDHTFEDFTQSSIELDAFVFRHLDQLFHNSTLNSTLDYEIRQDGNVFFL
                     HLLGCDTAGHSYRPYSAEYYDNVKYIDDQIPILIDKVNKFFADDKTAFIFTADHGMSA
                     FGSHGDGHPNNTRTPLVAWGAGLNKPVHNPFPVSDNYTENWELSSIKRNDVKQADIAS
                     LMSYLIGVNYPKNSVGELPIAYIDGKESDKLAALYNNARSILEQYLVKQDEVIDSQFF
                     YKEYFKFVEKSHSHYLEEIETLIQRISEGENYLEQEAITLTEELMQITLEGLHYLTTY
                     NWRFIRTIVTFGFVGWIFFSFIIFLKSFILENVIDDQKASPLSHAVFGSIGILLNWIL
                     FYQHSPFNFYMYLLFPLYFWSYIFTNRSVLRSGIKEFFKGTSPWKRVLITISIISVYE
                     GIVYGFFHRWTFTLITNILAFYPFICGVRELSVNILWIITSVLLSTFTLFDAVKIEDL
                     NQIHLAGLLIILSAFYALYKIHSRINSYTRAIFAIQISLVAAMLAVTHRSVISLQLRQ
                     GLPRESQVAGWIIFFVSLFVMPILHYRKPNNDYKVRLLIIYLTFAPSFIILTISFESL
                     FYFLFTSYMVQWIEIENKIKEMKTQKDENWLQVLRVSVIGFFLLQVAFFGTGNVASIS
                     SFSLESVCRLLPIFDPFLMGALLMLKLIIPYGLLSTCLGILNLKLNFKDYTISSLIIS
                     MSDILSLNFFYLLRTEGSWLDIGITISNYCLAILSSLFMLILEVLGHVLLKNVIIQDK
                     TKKTQ"
     gene            complement(141018..141089)
                     /locus_tag="tE(UUC)K"
                     /db_xref="GeneID:853691"
     tRNA            complement(141018..141089)
                     /locus_tag="tE(UUC)K"
                     /product="tRNA-Glu"
                     /note="Glutamate tRNA (tRNA-Glu), predicted by tRNAscan-SE
                     analysis; thiolation of uridine at wobble position (34)
                     requires Ncs6p"
                     /db_xref="SGD:S000006558"
                     /db_xref="GeneID:853691"
     gene            complement(<141794..>142819)
                     /gene="PIR1"
                     /locus_tag="YKL164C"
                     /gene_synonym="CCW6"
                     /db_xref="GeneID:853692"
     mRNA            complement(<141794..>142819)
                     /gene="PIR1"
                     /locus_tag="YKL164C"
                     /gene_synonym="CCW6"
                     /product="Pir1p"
                     /transcript_id="NM_001179730.1"
                     /db_xref="GI:296146221"
                     /db_xref="GeneID:853692"
     CDS             complement(141794..142819)
                     /gene="PIR1"
                     /locus_tag="YKL164C"
                     /gene_synonym="CCW6"
                     /note="O-glycosylated protein required for cell wall
                     stability; attached to the cell wall via beta-1,3-glucan;
                     mediates mitochondrial translocation of Apn1p; expression
                     regulated by the cell integrity pathway and by Swi5p
                     during the cell cycle; PIR1 has a paralog, YJL160C, that
                     arose from the whole genome duplication"
                     /codon_start=1
                     /product="Pir1p"
                     /protein_id="NP_012757.1"
                     /db_xref="GI:6322684"
                     /db_xref="SGD:S000001647"
                     /db_xref="GeneID:853692"
                     /translation="MQYKKSLVASALVATSLAAYAPKDPWSTLTPSATYKGGITDYSS
                     TFGIAVEPIATTASSKAKRAAAISQIGDGQIQATTKTTAAAVSQIGDGQIQATTKTKA
                     AAVSQIGDGQIQATTKTTSAKTTAAAVSQIGDGQIQATTKTKAAAVSQIGDGQIQATT
                     KTTAAAVSQIGDGQIQATTKTTAAAVSQIGDGQIQATTNTTVAPVSQITDGQIQATTL
                     TSATIIPSPAPAPITNGTDPVTAETCKSSGTLEMNLKGGILTDGKGRIGSIVANRQFQ
                     FDGPPPQAGAIYAAGWSITPEGNLAIGDQDTFYQCLSGNFYNLYDEHIGTQCNAVHLQ
                     AIDLLNC"
     gene            <144401..>145378
                     /gene="PIR3"
                     /locus_tag="YKL163W"
                     /gene_synonym="CCW8"
                     /db_xref="GeneID:853693"
     mRNA            <144401..>145378
                     /gene="PIR3"
                     /locus_tag="YKL163W"
                     /gene_synonym="CCW8"
                     /product="Pir3p"
                     /transcript_id="NM_001179729.1"
                     /db_xref="GI:296146222"
                     /db_xref="GeneID:853693"
     CDS             144401..145378
                     /gene="PIR3"
                     /locus_tag="YKL163W"
                     /gene_synonym="CCW8"
                     /note="O-glycosylated covalently-bound cell wall protein;
                     required for cell wall stability; expression is cell cycle
                     regulated, peaking in M/G1 and also subject to regulation
                     by the cell integrity pathway; coding sequence contains
                     length polymorphisms in different strains; PIR3 has a
                     paralog, HSP150, that arose from the whole genome
                     duplication"
                     /codon_start=1
                     /product="Pir3p"
                     /protein_id="NP_012758.1"
                     /db_xref="GI:6322685"
                     /db_xref="SGD:S000001646"
                     /db_xref="GeneID:853693"
                     /translation="MQYKKPLVVSALAATSLAAYAPKDPWSTLTPSATYKGGITDYSS
                     SFGIAIEAVATSASSVASSKAKRAASQIGDGQVQAATTTAAVSKKSTAAAVSQITDGQ
                     VQAAKSTAAAVSQITDGQVQAAKSTAAAVSQITDGQVQAAKSTAAAVSQITDGQVQAA
                     KSTAAAASQISDGQVQATTSTKAAASQITDGQIQASKTTSGASQVSDGQVQATAEVKD
                     ANDPVDVVSCNNNSTLSMSLSKGILTDRKGRIGSIVANRQFQFDGPPPQAGAIYAAGW
                     SITPEGNLALGDQDTFYQCLSGDFYNLYDKHIGSQCHEVYLQAIDLIDC"
     STS             145787..145892
                     /standard_name="px-18f6"
                     /db_xref="UniSTS:258336"
     gene            complement(<147630..>148838)
                     /locus_tag="YKL162C"
                     /db_xref="GeneID:853695"
     mRNA            complement(<147630..>148838)
                     /locus_tag="YKL162C"
                     /product="hypothetical protein"
                     /transcript_id="NM_001179728.1"
                     /db_xref="GI:296146223"
                     /db_xref="GeneID:853695"
     CDS             complement(147630..148838)
                     /locus_tag="YKL162C"
                     /note="hypothetical protein; green fluorescent protein
                     (GFP)-fusion protein localizes to the mitochondrion"
                     /codon_start=1
                     /product="hypothetical protein"
                     /protein_id="NP_012760.1"
                     /db_xref="GI:6322687"
                     /db_xref="SGD:S000001645"
                     /db_xref="GeneID:853695"
                     /translation="MMKRLHPLRIQVHLKSDYPLFTFEQLLSTNGIRRGQTARISLKD
                     YIEWQNFPNIMKRENFFTQRKPVTTTAKEEPFSFDNILDCEPQFSKCLAKWLLVNYKL
                     NDYPYYDLNIVNIYTDLPQAIQICKNLMSYLKSTLSDNMFQKIKYFMVPLYKCDKIPS
                     KLLDGIPGSVSLVQDYPVSPYFLQKKFHIEDPIQILMLNDVIKYTTHDLVRYSSDDKG
                     WQQCFVDINKNGQKSKSFDSAIDYSCELALEQMFNDRSHVSPGKELYIPTKLIEILMT
                     IKNNIPEHRLFIVDTPQRSSPTIISLLKSLISPRPTGSSQIVQPYSDSIFSDKRSGRI
                     CFMTDFLQLQNIYNGINSSSSSCEVEDVADFVEKWISPSERSTLSSQNGNRPQLEDIK
                     NSSLAVLHST"
     gene            complement(<149386..>150687)
                     /gene="KDX1"
                     /locus_tag="YKL161C"
                     /gene_synonym="MLP1"
                     /db_xref="GeneID:853696"
     mRNA            complement(<149386..>150687)
                     /gene="KDX1"
                     /locus_tag="YKL161C"
                     /gene_synonym="MLP1"
                     /product="putative protein kinase KDX1"
                     /transcript_id="NM_001179727.1"
                     /db_xref="GI:296146224"
                     /db_xref="GeneID:853696"
     CDS             complement(149386..150687)
                     /gene="KDX1"
                     /locus_tag="YKL161C"
                     /gene_synonym="MLP1"
                     /EC_number="2.7.11.1"
                     /note="Protein kinase; implicated in Slt2p
                     mitogen-activated (MAP) kinase signaling pathway;
                     interacts with numerous components in the mating pheromone
                     and CWI MAPK pathways; associates with Rlm1p; KDX1 has a
                     paralog, SLT2, that arose from the whole genome
                     duplication"
                     /codon_start=1
                     /product="putative protein kinase KDX1"
                     /protein_id="NP_012761.1"
                     /db_xref="GI:6322688"
                     /db_xref="SGD:S000001644"
                     /db_xref="GeneID:853696"
                     /translation="MATDTERCIFRAFGQDFILNKHFHLTGKIGRGSHSLICSSTYTE
                     SNEETHVAIRKIPNAFGNKLSCKRTLRELKLLRHLRGHPNIVWLFDTDIVFYPNGALN
                     GVYLYEELMECDLSQIIRSEQRLEDAHFQSFIYQILCALKYIHSANVLHCDLKPKNLL
                     VNSDCQLKICNFGLSCSYSENHKVNDGFIKGYITSIWYKAPEILLNYQECTKAVDIWS
                     TGCILAELLGRKPMFEGKDYVDHLNHILQILGTPPEETLQEIASQKVYNYIFQFGNIP
                     GRSFESILPGANPEALELLKKMLEFDPKKRITVEDALEHPYLSMWHDIDEEFSCQKTF
                     RFEFEHIESMAELGNEVIKEVFDFRKVVRKHPISGDSPSSSLSLEDAIPQEVVQVHPS
                     RKVLPSYSPEFSYVSQLPSLTTTQPYQNLMGISSNSFQGVN"
     rep_origin      153020..153135
                     /note="ARS1106;
                     Autonomously Replicating Sequence"
                     /db_xref="SGD:S000118402"
     gene            <153269..>153706
                     /gene="ELF1"
                     /locus_tag="YKL160W"
                     /db_xref="GeneID:853697"
     mRNA            <153269..>153706
                     /gene="ELF1"
                     /locus_tag="YKL160W"
                     /product="Elf1p"
                     /transcript_id="NM_001179726.1"
                     /db_xref="GI:296146225"
                     /db_xref="GeneID:853697"
     CDS             153269..153706
                     /gene="ELF1"
                     /locus_tag="YKL160W"
                     /note="Transcription elongation factor with a conserved
                     zinc finger domain; implicated in the maintenance of
                     proper chromatin structure in actively transcribed
                     regions; deletion inhibits Brome mosaic virus (BMV) gene
                     expression"
                     /codon_start=1
                     /product="Elf1p"
                     /protein_id="NP_012762.1"
                     /db_xref="GI:6322689"
                     /db_xref="SGD:S000001643"
                     /db_xref="GeneID:853697"
                     /translation="MGKRKKSTRKPTKRLVQKLDTKFNCLFCNHEKSVSCTLDKKNSI
                     GTLSCKICGQSFQTRINSLSQPVDVYSDWFDAVEEVNSGRGSDTDDGDEGSDSDYESD
                     SEQDAKTQNDGEIDSDEEEVDSDEERIGQVKRGRGALVDSDDE"
     gene            complement(<153816..>154451)
                     /gene="RCN1"
                     /locus_tag="YKL159C"
                     /db_xref="GeneID:853698"
     mRNA            complement(<153816..>154451)
                     /gene="RCN1"
                     /locus_tag="YKL159C"
                     /product="Rcn1p"
                     /transcript_id="NM_001179725.1"
                     /db_xref="GI:296146226"
                     /db_xref="GeneID:853698"
     CDS             complement(153816..154451)
                     /gene="RCN1"
                     /locus_tag="YKL159C"
                     /note="Protein involved in calcineurin regulation during
                     calcium signaling; has similarity to H. sapiens DSCR1
                     which is found in the Down Syndrome candidate region"
                     /codon_start=1
                     /product="Rcn1p"
                     /protein_id="NP_012763.1"
                     /db_xref="GI:6322690"
                     /db_xref="SGD:S000001642"
                     /db_xref="GeneID:853698"
                     /translation="MGNIITDTIIITSDKCDIVDNDNVERIQVWLSKNILRKFQINEN
                     EPLQLIILKRFKRILLICPSHDISQHVMDASRALEMENFNFSYSLQDGQRNLTKQYLK
                     VPESEKMFLISPPASPPPEFDFSKCEDAPQRHIQSHIQQDQQQRLEASQLLPNNPDKN
                     NNGTFTLLKSKVGAITIDRCPTNDGNGQMQLADHVKTAFPPKSIFDTDDDD"
     gene            <154991..>158232
                     /gene="APE2"
                     /locus_tag="YKL157W"
                     /gene_synonym="LAP1; YKL158W"
                     /db_xref="GeneID:853699"
     mRNA            join(<154991..155271,155655..>158232)
                     /gene="APE2"
                     /locus_tag="YKL157W"
                     /gene_synonym="LAP1; YKL158W"
                     /product="Ape2p"
                     /transcript_id="NM_001179723.2"
                     /db_xref="GI:330443643"
                     /db_xref="GeneID:853699"
     CDS             join(154991..155271,155655..158232)
                     /gene="APE2"
                     /locus_tag="YKL157W"
                     /gene_synonym="LAP1; YKL158W"
                     /EC_number="3.4.11.-"
                     /note="Aminopeptidase yscII; may have a role in obtaining
                     leucine from dipeptide substrates; APE2 has a paralog,
                     AAP1, that arose from the whole genome duplication"
                     /codon_start=1
                     /product="Ape2p"
                     /protein_id="NP_012765.3"
                     /db_xref="GI:330443644"
                     /db_xref="SGD:S000001640"
                     /db_xref="GeneID:853699"
                     /translation="MPIVRWLLLKSAVRGSSLIGKAHPCLRSIAAHPRYLSNVYSPPA
                     GVSRSLRINVMWKQSKLTPPRFVKIMNRRPLFTETSHACAKCQKTSQLLNKTPNREIL
                     PDNVVPLHYDLTVEPDFKTFKFEGSVKIELKINNPAIDTVTLNTVDTDIHSAKIGDVT
                     SSEIISEEEQQVTTFAFPKGTMSSFKGNAFLDIKFTGILNDNMAGFYRAKYEDKLTGE
                     TKYMATTQMEPTDARRAFPCFDEPNLKASFAITLVSDPSLTHLSNMDVKNEYVKDGKK
                     VTLFNTTPKMSTYLVAFIVAELKYVESKNFRIPVRVYATPGNEKHGQFAADLTAKTLA
                     FFEKTFGIQYPLPKMDNVAVHEFSAGAMENWGLVTYRVVDLLLDKDNSTLDRIQRVAE
                     VVQHELAHQWFGNLVTMDWWEGLWLNEGFATWMSWYSCNEFQPEWKVWEQYVTDTLQH
                     ALSLDSLRSSHPIEVPVKKADEINQIFDAISYSKGASLLRMISKWLGEETFIKGVSQY
                     LNKFKYGNAKTEDLWDALADASGKDVRSVMNIWTKKVGFPVISVSEDGNGKITFRQNR
                     YLSTADVKPDEDKTIYPVFLALKTKNGVDSSVVLSERSKTIELEDPTFFKVNSEQSGI
                     YITSYTDERWAKLGQQADLLSVEDRVGLVADVKTLSASGYTSTTNFLNLVSKWNNEKS
                     FVVWDQIINSISSMKSTWLFEPKETQDALDNFTKQLISGMTHHLGWEFKSSDSFSTQR
                     LKVTMFGAACAARDADVEKAALKMFTDYCSGNKEAIPALIKPIVFNTVARVGGAENYE
                     KVYKIYLDPISNDEKLAALRSLGRFKEPKLLERTLGYLFDGTVLNQDIYIPMQGMRAH
                     QEGVEALWNWVKKNWDELVKRLPPGLSMLGSVVTLGTSGFTSMQKIDEIKKFFATKST
                     KGFDQSLAQSLDTITSKAQWVNRDRDVVNKYLKENGYY"
     gene            <158613..>159212
                     /gene="RPS27A"
                     /locus_tag="YKL156W"
                     /db_xref="GeneID:853700"
     mRNA            join(<158613..158615,158967..>159212)
                     /gene="RPS27A"
                     /locus_tag="YKL156W"
                     /product="ribosomal 40S subunit protein S27A"
                     /transcript_id="NM_001179722.1"
                     /db_xref="GI:296146228"
                     /db_xref="GeneID:853700"
     CDS             join(158613..158615,158967..159212)
                     /gene="RPS27A"
                     /locus_tag="YKL156W"
                     /note="Protein component of the small (40S) ribosomal
                     subunit; homologous to mammalian ribosomal protein S27, no
                     bacterial homolog; RPS27A has a paralog, RPS27B, that
                     arose from the whole genome duplication; protein abundance
                     increases in response to DNA replication stress"
                     /codon_start=1
                     /product="ribosomal 40S subunit protein S27A"
                     /protein_id="NP_012766.1"
                     /db_xref="GI:6322693"
                     /db_xref="SGD:S000001639"
                     /db_xref="GeneID:853700"
                     /translation="MVLVQDLLHPTAASEARKHKLKTLVQGPRSYFLDVKCPGCLNIT
                     TVFSHAQTAVTCESCSTILCTPTGGKAKLSEGTSFRRK"
     gene            complement(<159456..>161342)
                     /gene="RSM22"
                     /locus_tag="YKL155C"
                     /db_xref="GeneID:853701"
     mRNA            complement(<159456..>161342)
                     /gene="RSM22"
                     /locus_tag="YKL155C"
                     /product="mitochondrial 37S ribosomal protein RSM22"
                     /transcript_id="NM_001179721.1"
                     /db_xref="GI:296146229"
                     /db_xref="GeneID:853701"
     CDS             complement(159456..161342)
                     /gene="RSM22"
                     /locus_tag="YKL155C"
                     /EC_number="2.1.1.-"
                     /note="Mitochondrial ribosomal protein of the small
                     subunit; also predicted to be an
                     S-adenosylmethionine-dependent methyltransferase"
                     /codon_start=1
                     /product="mitochondrial 37S ribosomal protein RSM22"
                     /protein_id="NP_012767.1"
                     /db_xref="GI:6322694"
                     /db_xref="SGD:S000001638"
                     /db_xref="GeneID:853701"
                     /translation="MMKRCFSILPQNVRFSSKFTSLNLPKLDLADFIDSNKRGINVLP
                     SYRDETASTTQATNSKELRLLSKTLQGQSYRDQLELNPDVSKAINNNIMAVHIPNNLR
                     RVATNYYKEIQEPNSLHRPCRTKMEVDAHIASIFLQNYGSIFQSLKELQKRVGPDNFK
                     PQRILDVGYGPATGIVALNDILGPNYRPDLKDAVILGNAEMQERAKIILSRQLNEVVD
                     TVEENVSTEKEQETDRRNKNFQEDEHIGEVMTKKINIMTNLRSSIPASKEYDLIILTH
                     QLLHDGNQFPIQVDENIEHYLNILAPGGHIVIIERGNPMGFEIIARARQITLRPENFP
                     DEFGKIPRPWSRGVTVRGKKDAELGNISSNYFLKVIAPCPHQRKCPLQVGNPNFYTHK
                     EGKDLKFCNFQKSIKRPKFSIELKKGKLLATSWDGSQGNASRLKGTGRRNGRDYEILN
                     YSYLIFERSHKDENTLKEIKKLRNENVNGKYDIGSLGDDTQNSWPRIINDPVKRKGHV
                     MMDLCAPSGELEKWTVSRSFSKQIYHDARKSKKGDLWASAAKTQIKGLGDLNVKKFHK
                     LEKERIKQLKKEERQKARKAMESYNELEDSLQFDDHQFSNFEVMKKLSTFHGNDFLQH
                     VNRK"
     gene            <161601..>162335
                     /gene="SRP102"
                     /locus_tag="YKL154W"
                     /db_xref="GeneID:853702"
     mRNA            <161601..>162335
                     /gene="SRP102"
                     /locus_tag="YKL154W"
                     /product="Signal recognition particle receptor subunit
                     beta"
                     /transcript_id="NM_001179720.1"
                     /db_xref="GI:296146230"
                     /db_xref="GeneID:853702"
     CDS             161601..162335
                     /gene="SRP102"
                     /locus_tag="YKL154W"
                     /note="Signal recognition particle (SRP) receptor beta
                     subunit; involved in SRP-dependent protein targeting;
                     anchors the alpha subunit, Srp101p to the ER membrane"
                     /codon_start=1
                     /product="Signal recognition particle receptor subunit
                     beta"
                     /protein_id="NP_012768.1"
                     /db_xref="GI:6322695"
                     /db_xref="SGD:S000001637"
                     /db_xref="GeneID:853702"
                     /translation="MLSNTLIIACLLVIGTTIALIAVQKASSKTGIKQKSYQPSIIIA
                     GPQNSGKTSLLTLLTTDSVRPTVVSQEPLSAADYDGSGVTLVDFPGHVKLRYKLSDYL
                     KTRAKFVKGLIFMVDSTVDPKKLTTTAEFLVDILSITESSCENGIDILIACNKSELFT
                     ARPPSKIKDALESEIQKVIERRKKSLNEVERKINEEDYAENTLDVLQSTDGFKFANLE
                     ASVVAFEGSINKRKISQWREWIDEKL"
     gene            complement(162487..162558)
                     /locus_tag="tR(UCU)K"
                     /db_xref="GeneID:853703"
     tRNA            complement(162487..162558)
                     /locus_tag="tR(UCU)K"
                     /product="tRNA-Arg"
                     /note="Arginine tRNA (tRNA-Arg), predicted by tRNAscan-SE
                     analysis; one of 11 nuclear tRNA genes containing the
                     tDNA-anticodon UCU (converted to mcm5-UCU in the mature
                     tRNA), decodes AGA codons into arginine, one of 19 nuclear
                     tRNAs for arginine"
                     /db_xref="SGD:S000006716"
                     /db_xref="GeneID:853703"
     LTR             162831..163169
                     /note="Ty1 LTR"
                     /db_xref="SGD:S000007056"
     gene            complement(<163642..>164385)
                     /gene="GPM1"
                     /locus_tag="YKL152C"
                     /db_xref="GeneID:853705"
     mRNA            complement(<163642..>164385)
                     /gene="GPM1"
                     /locus_tag="YKL152C"
                     /product="phosphoglycerate mutase GPM1"
                     /transcript_id="NM_001179718.1"
                     /db_xref="GI:296146231"
                     /db_xref="GeneID:853705"
     CDS             complement(163642..164385)
                     /gene="GPM1"
                     /locus_tag="YKL152C"
                     /EC_number="5.4.2.11"
                     /note="Tetrameric phosphoglycerate mutase; mediates the
                     conversion of 3-phosphoglycerate to 2-phosphoglycerate
                     during glycolysis and the reverse reaction during
                     gluconeogenesis"
                     /codon_start=1
                     /product="phosphoglycerate mutase GPM1"
                     /protein_id="NP_012770.1"
                     /db_xref="GI:6322697"
                     /db_xref="SGD:S000001635"
                     /db_xref="GeneID:853705"
                     /translation="MPKLVLVRHGQSEWNEKNLFTGWVDVKLSAKGQQEAARAGELLK
                     EKKVYPDVLYTSKLSRAIQTANIALEKADRLWIPVNRSWRLNERHYGDLQGKDKAETL
                     KKFGEEKFNTYRRSFDVPPPPIDASSPFSQKGDERYKYVDPNVLPETESLALVIDRLL
                     PYWQDVIAKDLLSGKTVMIAAHGNSLRGLVKHLEGISDADIAKLNIPTGIPLVFELDE
                     NLKPSKPSYYLDPEAAAAGAAAVANQGKK"
     gene            complement(<164917..>165930)
                     /locus_tag="YKL151C"
                     /db_xref="GeneID:853706"
     mRNA            complement(<164917..>165930)
                     /locus_tag="YKL151C"
                     /product="NADHX dehydratase"
                     /transcript_id="NM_001179717.1"
                     /db_xref="GI:296146232"
                     /db_xref="GeneID:853706"
     CDS             complement(164917..165930)
                     /locus_tag="YKL151C"
                     /EC_number="4.2.1.93"
                     /note="NADHX dehydratase; converts (S)-NADHX to NADH in an
                     ATP-dependent manner; homologous to Carkd in mammals, and
                     the C-terminal domain of YjeF in E.coli; enzyme is
                     widespread in eukaryotes, prokaryotes and archaea; YKL151C
                     promoter contains STREs (stress response elements) and
                     expression is induced by heat shock or methyl
                     methanesulfonate; green fluorescent protein (GFP)-fusion
                     protein localizes to the cytoplasm; protein abundance
                     increases in response to DNA replication stress"
                     /codon_start=1
                     /product="NADHX dehydratase"
                     /protein_id="NP_012771.1"
                     /db_xref="GI:6322698"
                     /db_xref="SGD:S000001634"
                     /db_xref="GeneID:853706"
                     /translation="MLAELSHRELIKLAQKRCIPPLLPKFHKGQSGGRVCIIGGCEDY
                     TGAPYFSANATALMGCDLTHVICEYNAGTVIKSYTPNLMVHPYLRMSNTKLDVDMDEQ
                     RKKINSLLDRIHVVVIGPGLGRDPLMLKSIKDIIRYILEKHEGKIPLVIDADGLFLVT
                     QDSEVKEMLKSYPKGRVILTPNVVEFKRLCDAIGKKGDSHSEMGSLIAQELNCIVVEK
                     GQSDKIFSPDSEKDMLTNSEEGSNKRVGGQGDTLTGAISCMLAFSRAMYDFKICEQEE
                     KGESSNDKPLKNWVDYAMLSCYAGCTITRECSRLGFKAKGRAMQTTDLNDRVGEVFAK
                     LFG"
     gene            <166544..>167452
                     /gene="MCR1"
                     /locus_tag="YKL150W"
                     /db_xref="GeneID:853707"
     mRNA            <166544..>167452
                     /gene="MCR1"
                     /locus_tag="YKL150W"
                     /product="Mcr1p"
                     /transcript_id="NM_001179716.1"
                     /db_xref="GI:296146233"
                     /db_xref="GeneID:853707"
     CDS             166544..167452
                     /gene="MCR1"
                     /locus_tag="YKL150W"
                     /EC_number="1.6.2.2"
                     /note="Mitochondrial NADH-cytochrome b5 reductase;
                     involved in ergosterol biosynthesis"
                     /codon_start=1
                     /product="Mcr1p"
                     /protein_id="NP_012772.1"
                     /db_xref="GI:6322699"
                     /db_xref="SGD:S000001633"
                     /db_xref="GeneID:853707"
                     /translation="MFSRLSRSHSKALPIALGTVAIAAATAFYFANRNQHSFVFNESN
                     KVFKGDDKWIDLPISKIEEESHDTRRFTFKLPTEDSEMGLVLASALFAKFVTPKGSNV
                     VRPYTPVSDLSQKGHFQLVVKHYEGGKMTSHLFGLKPNDTVSFKGPIMKWKWQPNQFK
                     SITLLGAGTGINPLYQLAHHIVENPNDKTKVNLLYGNKTPQDILLRKELDALKEKYPD
                     KFNVTYFVDDKQDDQDFDGEISFISKDFIQEHVPGPKESTHLFVCGPPPFMNAYSGEK
                     KSPKDQGELIGILNNLGYSKDQVFKF"
     gene            complement(<167612..>168829)
                     /gene="DBR1"
                     /locus_tag="YKL149C"
                     /gene_synonym="PRP26"
                     /db_xref="GeneID:853708"
     mRNA            complement(<167612..>168829)
                     /gene="DBR1"
                     /locus_tag="YKL149C"
                     /gene_synonym="PRP26"
                     /product="Dbr1p"
                     /transcript_id="NM_001179715.1"
                     /db_xref="GI:296146234"
                     /db_xref="GeneID:853708"
     CDS             complement(167612..168829)
                     /gene="DBR1"
                     /locus_tag="YKL149C"
                     /gene_synonym="PRP26"
                     /EC_number="3.1.-.-"
                     /note="RNA lariat debranching enzyme; catalyzes
                     debranching of lariat introns formed during pre-mRNA
                     splicing; required for efficient Ty1 transposition;
                     knockdown of human homolog Dbr1 rescues toxicity of
                     RNA-binding proteins TDP-43 and FUS which are implicated
                     in amyotrophic lateral sclerosis (ALS), suggests potential
                     therapeutic target for ALS and related TDP-43
                     proteinopathies"
                     /codon_start=1
                     /product="Dbr1p"
                     /protein_id="NP_012773.1"
                     /db_xref="GI:6322700"
                     /db_xref="SGD:S000001632"
                     /db_xref="GeneID:853708"
                     /translation="MTKLRIAVQGCCHGQLNQIYKEVSRIHAKTPIDLLIILGDFQSI
                     RDGQDFKSIAIPPKYQRLGDFISYYNNEIEAPVPTIFIGGNHESMRHLMLLPHGGYVA
                     KNIFYMGYSNVIWFKGIRIGSLSGIWKEWDFNKQRPDWNDLENNNWKANIRNLYHVRI
                     SDIAPLFMIKHRIDIMLSHDWPNGVVYHGDTKHLLKLKPFFEQDIKEGKLGSPVTWQL
                     LRDLRPQWWLSAHLHVRFMASIKHNKRSHEPPNKSTSKTKKNNNEIDLDLSSDEDERS
                     GIMNCQEENEYDSKYGETRFLALDKCLPRRRWLEILEIEPDTSHASWKDENHRMFWDP
                     EFINNLVICQKNKNLLSNKPFNSVNWIELSQSNREEGRDIDWENYAIPAYTLDIQKDE
                     VRQTKAFISKFMT"
     gene            complement(<169207..>171129)
                     /gene="SDH1"
                     /locus_tag="YKL148C"
                     /db_xref="GeneID:853709"
     mRNA            complement(<169207..>171129)
                     /gene="SDH1"
                     /locus_tag="YKL148C"
                     /product="succinate dehydrogenase flavoprotein subunit
                     SDH1"
                     /transcript_id="NM_001179714.1"
                     /db_xref="GI:296146235"
                     /db_xref="GeneID:853709"
     CDS             complement(169207..171129)
                     /gene="SDH1"
                     /locus_tag="YKL148C"
                     /EC_number="1.3.5.1"
                     /note="Flavoprotein subunit of succinate dehydrogenase;
                     couples the oxidation of succinate to the transfer of
                     electrons to ubiquinone as part of the TCA cycle and the
                     mitochondrial respiratory chain; FAD binding to Sdh1p is
                     required for the assembly of the succinate dehydrogenase
                     subunits; SDH1 has a paralog, YJL045W, that arose from the
                     whole genome duplication"
                     /codon_start=1
                     /product="succinate dehydrogenase flavoprotein subunit
                     SDH1"
                     /protein_id="NP_012774.1"
                     /db_xref="GI:6322701"
                     /db_xref="SGD:S000001631"
                     /db_xref="GeneID:853709"
                     /translation="MLSLKKSALSKLTLLRNTRTFTSSALVRQTQGSVNGSASRSADG
                     KYHIIDHEYDCVVIGAGGAGLRAAFGLAEAGYKTACISKLFPTRSHTVAAQGGINAAL
                     GNMHKDNWKWHMYDTVKGSDWLGDQDSIHYMTREAPKSIIELEHYGVPFSRTENGKIY
                     QRAFGGQTKEYGKGAQAYRTCAVADRTGHALLHTLYGQALRHDTHFFIEYFALDLLTH
                     NGEVVGVIAYNQEDGTIHRFRAHKTIIATGGYGRAYFSCTSAHTCTGDGNAMVSRAGF
                     PLQDLEFVQFHPSGIYGSGCLITEGARGEGGFLVNSEGERFMERYAPTAKDLACRDVV
                     SRAITMEIREGRGVGKKKDHMYLQLSHLPPEVLKERLPGISETAAIFAGVDVTKEPIP
                     IIPTVHYNMGGIPTKWNGEALTIDEETGEDKVIPGLMACGEAACVSVHGANRLGANSL
                     LDLVVFGRAVAHTVADTLQPGLPHKPLPSDLGKESIANLDKLRNANGSRSTAEIRMNM
                     KQTMQKDVSVFRTQSSLDEGVRNITAVEKTFDDVKTTDRSMIWNSDLVETLELQNLLT
                     CASQTAVSAANRKESRGAHAREDYPNRDDEHWMKHTLSWQKDVAAPVTLKYRRVIDHT
                     LDEKECPSVPPTVRAY"
     gene            <171783..>173861
                     /gene="AVT3"
                     /locus_tag="YKL146W"
                     /db_xref="GeneID:853710"
     mRNA            <171783..>173861
                     /gene="AVT3"
                     /locus_tag="YKL146W"
                     /product="Avt3p"
                     /transcript_id="NM_001179712.1"
                     /db_xref="GI:296146236"
                     /db_xref="GeneID:853710"
     CDS             171783..173861
                     /gene="AVT3"
                     /locus_tag="YKL146W"
                     /note="Vacuolar transporter; exports large neutral amino
                     acids from the vacuole; member of a family of seven S.
                     cerevisiae genes (AVT1-7) related to vesicular
                     GABA-glycine transporters"
                     /codon_start=1
                     /product="Avt3p"
                     /protein_id="NP_012776.1"
                     /db_xref="GI:6322702"
                     /db_xref="SGD:S000001629"
                     /db_xref="GeneID:853710"
                     /translation="MNGKEVSSGSGRTQSNNNKKNNNGGSTGISHASGSPLTDGNGGN
                     SNGNSRSRSRSRKSSGTTGGLLKKPPLLVNNEAVHASVPDASHTSCNNGTLEVSINNP
                     EPHVVDAVARHLIRNPSNSLQLQGGDITRDLYKWTNDHPSSPSQYQYPSQPALSTSIP
                     SQAPSFSNRKRSMSFSAASIASSSHLNNNSEANGNPLAAIGLAPAPMTHEEIRAPGGF
                     RRSFIIQKRRKHNVDAPIPNFFTRNFIEFLTLYGHFAGEDLSEEEEEEEETEEEPEEE
                     ALETESTQLVSREHGRHPHKSSTVKAVLLLLKSFVGTGVLFLPKAFHNGGWGFSALCL
                     LSCALISYGCFVSLITTKDKVGVDGYGDMGRILYGPKMKFAILSSIALSQIGFSAAYT
                     VFTATNLQVFSENFFHLKPGSISLATYIFAQVLIFVPLSLTRNIAKLSGTALIADLFI
                     LLGLVYVYVYSIYYIAVNGVASDTMLMFNKADWSLFIGTAIFTFEGIGLLIPIQESMK
                     HPKHFRPSLSAVMCIVAVIFISCGLLCYAAFGSDVKTVVLLNFPQDTSYTLTVQLLYA
                     LAILLSTPLQLFPAIRILENWTFPSNASGKYNPKVKWLKNYFRCAIVVLTSILAWVGA
                     NDLDKFVSLVGSFACIPLIYIYPPLLHYKASILSGTSRARLLLDLIVIVFGVAVMAYT
                     SWQTIKMWSQ"
     gene            <174213..>175616
                     /gene="RPT1"
                     /locus_tag="YKL145W"
                     /gene_synonym="CIM5; YTA3"
                     /db_xref="GeneID:853712"
     mRNA            <174213..>175616
                     /gene="RPT1"
                     /locus_tag="YKL145W"
                     /gene_synonym="CIM5; YTA3"
                     /product="proteasome regulatory particle base subunit
                     RPT1"
                     /transcript_id="NM_001179711.1"
                     /db_xref="GI:296146237"
                     /db_xref="GeneID:853712"
     CDS             174213..175616
                     /gene="RPT1"
                     /locus_tag="YKL145W"
                     /gene_synonym="CIM5; YTA3"
                     /note="ATPase of the 19S regulatory particle of the 26S
                     proteasome; one of six ATPases of the regulatory particle;
                     involved in the degradation of ubiquitinated substrates;
                     required for optimal CDC20 transcription; interacts with
                     Rpn12p and Ubr1p; mutant has aneuploidy tolerance"
                     /codon_start=1
                     /product="proteasome regulatory particle base subunit
                     RPT1"
                     /protein_id="NP_012777.1"
                     /db_xref="GI:6322704"
                     /db_xref="SGD:S000001628"
                     /db_xref="GeneID:853712"
                     /translation="MPPKEDWEKYKAPLEDDDKKPDDDKIVPLTEGDIQVLKSYGAAP
                     YAAKLKQTENDLKDIEARIKEKAGVKESDTGLAPSHLWDIMGDRQRLGEEHPLQVARC
                     TKIIKGNGESDETTTDNNNSGNSNSNSNQQSTDADEDDEDAKYVINLKQIAKFVVGLG
                     ERVSPTDIEEGMRVGVDRSKYNIELPLPPRIDPSVTMMTVEEKPDVTYSDVGGCKDQI
                     EKLREVVELPLLSPERFATLGIDPPKGILLYGPPGTGKTLCARAVANRTDATFIRVIG
                     SELVQKYVGEGARMVRELFEMARTKKACIIFFDEIDAVGGARFDDGAGGDNEVQRTML
                     ELITQLDGFDPRGNIKVMFATNRPNTLDPALLRPGRIDRKVEFSLPDLEGRANIFRIH
                     SKSMSVERGIRWELISRLCPNSTGAELRSVCTEAGMFAIRARRKVATEKDFLKAVDKV
                     ISGYKKFSSTSRYMQYN"
     gene            complement(<175843..>176481)
                     /gene="RPC25"
                     /locus_tag="YKL144C"
                     /gene_synonym="YKL1"
                     /db_xref="GeneID:853713"
     mRNA            complement(<175843..>176481)
                     /gene="RPC25"
                     /locus_tag="YKL144C"
                     /gene_synonym="YKL1"
                     /product="DNA-directed RNA polymerase III subunit RPC25"
                     /transcript_id="NM_001179710.1"
                     /db_xref="GI:296146238"
                     /db_xref="GeneID:853713"
     CDS             complement(175843..176481)
                     /gene="RPC25"
                     /locus_tag="YKL144C"
                     /gene_synonym="YKL1"
                     /note="RNA polymerase III subunit C25; required for
                     transcription initiation; forms a heterodimer with Rpc17p;
                     paralog of Rpb7p"
                     /codon_start=1
                     /product="DNA-directed RNA polymerase III subunit RPC25"
                     /protein_id="NP_012778.1"
                     /db_xref="GI:6322705"
                     /db_xref="SGD:S000001627"
                     /db_xref="GeneID:853713"
                     /translation="MFILSKIADLVRIPPDQFHRDTISAITHQLNNKFANKIIPNVGL
                     CITIYDLLTVEEGQLKPGDGSSYINVTFRAVVFKPFLGEIVTGWISKCTAEGIKVSLL
                     GIFDDIFIPQNMLFEGCYYTPEESAWIWPMDEETKLYFDVNEKIRFRIEREVFVDVKP
                     KSPKERELEERAQLENEIEGKNEETPQNEKPPAYALLGSCQTDGMGLVSWWE"
     gene            <176781..>178172
                     /gene="LTV1"
                     /locus_tag="YKL143W"
                     /gene_synonym="YKL2"
                     /db_xref="GeneID:853714"
     mRNA            <176781..>178172
                     /gene="LTV1"
                     /locus_tag="YKL143W"
                     /gene_synonym="YKL2"
                     /product="Ltv1p"
                     /transcript_id="NM_001179709.1"
                     /db_xref="GI:296146239"
                     /db_xref="GeneID:853714"
     CDS             176781..178172
                     /gene="LTV1"
                     /locus_tag="YKL143W"
                     /gene_synonym="YKL2"
                     /note="Component of the GSE complex; GSE is required for
                     proper sorting of amino acid permease Gap1p; required for
                     ribosomal small subunit export from nucleus; required for
                     growth at low temperature"
                     /codon_start=1
                     /product="Ltv1p"
                     /protein_id="NP_012779.1"
                     /db_xref="GI:6322706"
                     /db_xref="SGD:S000001626"
                     /db_xref="GeneID:853714"
                     /translation="MSKKFSSKNSQRYVVVHRPHDDPSFYDTDASAHVLVPVSNPNKT
                     SPEADLRKKDVSSTKPKGRRAHVGEAALYGINFDDSEYDYTQHLKPIGLDPENSIFIA
                     SKGNEQKVEKKNIEDLFIEPKYRRDEIEKDDALPVFQRGMAKPEYLLHQQDTTDEIRG
                     FKPDMNPALREVLEALEDEAYVVNDDVVVEDISKKTQLQGDNYGEEEKEDDIFAQLLG
                     SGEAKDEDEFEDEFDEWDIDNVENFEDENYVKEMAQFDNIENLEDLENIDYQADVRRF
                     QKDNSILEKHNSDDEFSNAGLDSVNPSEEEDVLGELPSIQDKSKTGKKKRKSRQKKGA
                     MSDVSGFSMSSSAIARTETMTVLDDQYDQIINGYENYEEELEEDEEQNYQPFDMSAER
                     SDFESMLDDFLDNYELESGGRKLAKKDKEIERLKEAADEVSKGKLSQRRNRERQEKKK
                     LEKVTNTLSSLKF"
     gene            <178515..>179174
                     /gene="MRP8"
                     /locus_tag="YKL142W"
                     /gene_synonym="YKL3"
                     /db_xref="GeneID:853715"
     mRNA            <178515..>179174
                     /gene="MRP8"
                     /locus_tag="YKL142W"
                     /gene_synonym="YKL3"
                     /product="Mrp8p"
                     /transcript_id="NM_001179708.1"
                     /db_xref="GI:296146240"
                     /db_xref="GeneID:853715"
     CDS             178515..179174
                     /gene="MRP8"
                     /locus_tag="YKL142W"
                     /gene_synonym="YKL3"
                     /note="hypothetical protein; undergoes sumoylation;
                     transcription induced under cell wall stress; protein
                     levels are reduced under anaerobic conditions; protein
                     abundance increases in response to DNA replication stress;
                     originally thought to be a mitochondrial ribosomal protein
                     based on sequence analysis"
                     /codon_start=1
                     /product="Mrp8p"
                     /protein_id="NP_012780.1"
                     /db_xref="GI:6322707"
                     /db_xref="SGD:S000001625"
                     /db_xref="GeneID:853715"
                     /translation="MSNEIELLQKQVSELQDLVKKQSLIISKTGERVLELQLDKQKHD
                     VTDFDSKFSKSISKKSGSATQFDATDFATNEDLVELVKELQGELNFIEERSIRRLVNS
                     LKKDDDDVIAPLPNADGDIPAISDGVFPKSLKEFKDIPDLKLVRLAKFYERLPPTLKE
                     QEDFENFLEGKVEAFHINETTDEEISKELEKFSKDELDDAFNDVARYLGLSLRRGTEI
                     W"
     gene            <179667..>180263
                     /gene="SDH3"
                     /locus_tag="YKL141W"
                     /gene_synonym="CYB3; YKL4"
                     /db_xref="GeneID:853716"
     mRNA            <179667..>180263
                     /gene="SDH3"
                     /locus_tag="YKL141W"
                     /gene_synonym="CYB3; YKL4"
                     /product="succinate dehydrogenase cytochrome b subunit
                     SDH3"
                     /transcript_id="NM_001179707.1"
                     /db_xref="GI:296146241"
                     /db_xref="GeneID:853716"
     CDS             179667..180263
                     /gene="SDH3"
                     /locus_tag="YKL141W"
                     /gene_synonym="CYB3; YKL4"
                     /note="Subunit of succinate dehydrogenase and of TIM22
                     translocase; functions as cytochrome b subunit of
                     succinate dehydrogenase, which couples oxidation of
                     succinate to transfer of electrons to ubiquinone as part
                     of the TCA cycle and the mitochondrial respiratory chain;
                     also required for mitochondrial inner membrane protein
                     import as part of the TIM22 complex; SDH3 has a paralog,
                     SHH3, that arose from the whole genome duplication"
                     /codon_start=1
                     /product="succinate dehydrogenase cytochrome b subunit
                     SDH3"
                     /protein_id="NP_012781.1"
                     /db_xref="GI:6322708"
                     /db_xref="SGD:S000001624"
                     /db_xref="GeneID:853716"
                     /translation="MSAMMVKLGLNKSALLLKPSAFSRAAALSSSRRLLFNTARTNFL
                     STSPLKNVASEMNTKAAIAEEQILNKQRAKRPISPHLTIYQPQLTWYLSSLHRISLVL
                     MGLGFYLFTILFGVSGLLGLGLTTEKVSNWYHQKFSKITEWSIKGSFAYLFAIHYGGA
                     IRHLIWDTAKELTLKGVYRTGYALIGFTAVLGTYLLTL"
     gene            <180779..>182425
                     /gene="TGL1"
                     /locus_tag="YKL140W"
                     /gene_synonym="YKL5"
                     /db_xref="GeneID:853717"
     mRNA            <180779..>182425
                     /gene="TGL1"
                     /locus_tag="YKL140W"
                     /gene_synonym="YKL5"
                     /product="Tgl1p"
                     /transcript_id="NM_001179706.1"
                     /db_xref="GI:296146242"
                     /db_xref="GeneID:853717"
     CDS             180779..182425
                     /gene="TGL1"
                     /locus_tag="YKL140W"
                     /gene_synonym="YKL5"
                     /EC_number="3.1.1.13"
                     /note="Steryl ester hydrolase; one of three gene products
                     (Yeh1p, Yeh2p, Tgl1p) responsible for steryl ester
                     hydrolase activity and involved in sterol homeostasis;
                     localized to lipid particle membranes"
                     /codon_start=1
                     /product="Tgl1p"
                     /protein_id="NP_012782.1"
                     /db_xref="GI:6322709"
                     /db_xref="SGD:S000001623"
                     /db_xref="GeneID:853717"
                     /translation="MYFPFLGRLSITDYIIVVLVYIESIISSVLKLIPQPMINLFEWL
                     INFSTSSDDNTIEEKLRSAPTIHEMCAIFDISVEDHLVRTEDNYILTLHRIPPISKNR
                     FNNKVVYLHHGLLMCSDVWCCNIERHKNLPFVLHDLGYDVWMGNNRGNKYSTAHLNKP
                     PKSNKFWDFSIDEFAFFDIPNSIEFILDITKVDKVICIGFSQGSAQMFAAFSLSEKLN
                     RKVSHFIAIAPAMTPKGLHNRIVDTLAKSSPGFMYLFFGRKIVLPSAVIWQRTLHPTL
                     FNLCIDIANKILFNWKSFNILPRQKIASYAKLYSTTSVKSIVHWFQILRSQKFQMFEE
                     SDNMLNSLTRPYQIANFPTRTNIKIPILLIYGGIDSLVDIDVMKKNLPFNSVFDVKVD
                     NYEHLDLIWGKDADTLVIAKVLRFIEFFNPGNVSVKTNQLLPSASLVEELPSTTWKTT
                     HPTHGLSYRTHSADRSPLSVQADEADEVHNADNSRFLRRVFSTSAIDEDNENEHQDDT
                     EDQIHKEQQRRLSAYLESSKDLRQLDANSSTTALDALNKE"
     gene            <182958..>184544
                     /gene="CTK1"
                     /locus_tag="YKL139W"
                     /db_xref="GeneID:853718"
     mRNA            <182958..>184544
                     /gene="CTK1"
                     /locus_tag="YKL139W"
                     /product="cyclin-dependent serine/threonine protein kinase
                     CTK1"
                     /transcript_id="NM_001179705.1"
                     /db_xref="GI:296146243"
                     /db_xref="GeneID:853718"
     CDS             182958..184544
                     /gene="CTK1"
                     /locus_tag="YKL139W"
                     /EC_number="2.7.11.23"
                     /note="Catalytic (alpha) subunit of C-terminal domain
                     kinase I (CTDK-I); phosphorylates both RNA pol II subunit
                     Rpo21p to affect transcription and pre-mRNA 3' end
                     processing, and ribosomal protein Rps2p to increase
                     translational fidelity; required for H3K36 trimethylation
                     but not dimethylation by Set2p; similar to the Drosophila
                     dCDK12 and human CDK12 and probably CDK13"
                     /codon_start=1
                     /product="cyclin-dependent serine/threonine protein kinase
                     CTK1"
                     /protein_id="NP_012783.1"
                     /db_xref="GI:6322710"
                     /db_xref="SGD:S000001622"
                     /db_xref="GeneID:853718"
                     /translation="MSYNNGNTYSKSYSRNNKRPLFGKRSPNPQSLARPPPPKRIRTD
                     SGYQSNMDNISSHRVNSNDQPGHTKSRGNNNLSRYNDTSFQTSSRYQGSRYNNNNTSY
                     ENRPKSIKRDETKAEFLSHLPKGPKSVEKSRYNNSSNTSNDIKNGYHASKYYNHKGQE
                     GRSVIAKKVPVSVLTQQRSTSVYLRIMQVGEGTYGKVYKAKNTNTEKLVALKKLRLQG
                     EREGFPITSIREIKLLQSFDHPNVSTIKEIMVESQKTVYMIFEYADNDLSGLLLNKEV
                     QISHSQCKHLFKQLLLGMEYLHDNKILHRDVKGSNILIDNQGNLKITDFGLARKMNSR
                     ADYTNRVITLWYRPPELLLGTTNYGTEVDMWGCGCLLVELFNKTAIFQGSNELEQIES
                     IFKIMGTPTINSWPTLYDMPWFFMIMPQQTTKYVNNFSEKFKSVLPSSKCLQLAINLL
                     CYDQTKRFSATEALQSDYFKEEPKPEPLVLDGLVSCHEYEVKLARKQKRPNILSTNTN
                     NKGNGNSNNNNNNNNDDDDK"
     gene            complement(<184803..>185012)
                     /gene="HSK3"
                     /locus_tag="YKL138C-A"
                     /db_xref="GeneID:853719"
     mRNA            complement(<184803..>185012)
                     /gene="HSK3"
                     /locus_tag="YKL138C-A"
                     /product="Hsk3p"
                     /transcript_id="NM_001184513.1"
                     /db_xref="GI:296146244"
                     /db_xref="GeneID:853719"
     CDS             complement(184803..185012)
                     /gene="HSK3"
                     /locus_tag="YKL138C-A"
                     /note="Essential subunit of the Dam1 complex (aka DASH
                     complex); complex couples kinetochores to the force
                     produced by MT depolymerization thereby aiding in
                     chromosome segregation; is transferred to the kinetochore
                     prior to mitosis"
                     /codon_start=1
                     /product="Hsk3p"
                     /protein_id="NP_690844.1"
                     /db_xref="GI:23270398"
                     /db_xref="SGD:S000028421"
                     /db_xref="GeneID:853719"
                     /translation="MNANKQRQYNQLAHELRELQTNLQETTKQLDIMSKQCNENLVGQ
                     LGKVHGSWLIGSYIYYMEQMLGKTQ"
     gene            complement(<185286..>185681)
                     /gene="MRPL31"
                     /locus_tag="YKL138C"
                     /db_xref="GeneID:853720"
     mRNA            complement(<185286..>185681)
                     /gene="MRPL31"
                     /locus_tag="YKL138C"
                     /product="mitochondrial 54S ribosomal protein YmL31"
                     /transcript_id="NM_001179704.1"
                     /db_xref="GI:296146245"
                     /db_xref="GeneID:853720"
     CDS             complement(185286..185681)
                     /gene="MRPL31"
                     /locus_tag="YKL138C"
                     /note="Mitochondrial ribosomal protein of the large
                     subunit"
                     /codon_start=1
                     /product="mitochondrial 54S ribosomal protein YmL31"
                     /protein_id="NP_012784.1"
                     /db_xref="GI:6322711"
                     /db_xref="SGD:S000001621"
                     /db_xref="GeneID:853720"
                     /translation="MFGPFKLTSPVAGGLLWKIPWRMSTHQKTRQRERLRNVDQVIKQ
                     LTLGLHVQRCQDKGLTYQEAMESKKKYKPRSKSLRLLNKPSVFPKENQMSSKDKYWTF
                     DKKAVGYRKGIHKVPKWTKISIRKAPKFF"
     gene            <185957..>186292
                     /gene="CMC1"
                     /locus_tag="YKL137W"
                     /db_xref="GeneID:853721"
     mRNA            <185957..>186292
                     /gene="CMC1"
                     /locus_tag="YKL137W"
                     /product="Cmc1p"
                     /transcript_id="NM_001179703.1"
                     /db_xref="GI:296146246"
                     /db_xref="GeneID:853721"
     CDS             185957..186292
                     /gene="CMC1"
                     /locus_tag="YKL137W"
                     /note="Copper-binding protein of the mitochondrial
                     intermembrane space; evolutionarily conserved; may be
                     involved in delivering copper from the matrix to the
                     cytochrome c oxidase complex; contains a twin CX9C motif"
                     /codon_start=1
                     /product="Cmc1p"
                     /protein_id="NP_012785.2"
                     /db_xref="GI:83722563"
                     /db_xref="SGD:S000001620"
                     /db_xref="GeneID:853721"
                     /translation="MEQNKDPQMISKHSSRLPIWVLSPREEQQARKNLKTETYKKCAN
                     FVQAMADCAKANGMKVFPTCDKQRDEMKSCLLFYQTDEKYLDGERDKIVLEKINKLEK
                     LCQKQSSTK"
     gene            complement(<186460..>188640)
                     /gene="APL2"
                     /locus_tag="YKL135C"
                     /db_xref="GeneID:853723"
     mRNA            complement(<186460..>188640)
                     /gene="APL2"
                     /locus_tag="YKL135C"
                     /product="Apl2p"
                     /transcript_id="NM_001179701.1"
                     /db_xref="GI:296146247"
                     /db_xref="GeneID:853723"
     CDS             complement(186460..188640)
                     /gene="APL2"
                     /locus_tag="YKL135C"
                     /note="Beta-adaptin subunit of the clathrin-associated
                     protein (AP-1) complex; binds clathrin; involved in
                     clathrin-dependent Golgi protein sorting; protein
                     abundance increases in response to DNA replication stress"
                     /codon_start=1
                     /product="Apl2p"
                     /protein_id="NP_012787.1"
                     /db_xref="GI:6322714"
                     /db_xref="SGD:S000001618"
                     /db_xref="GeneID:853723"
                     /translation="MPPLDKRIKKFLKDSIRIAPKISGKGELSELRTGLVSQYPQTRK
                     DAIKKTIQQMTLGKDVSSLFPDVLKNIATIDVEQKKLVYLYVMNYAETHPELCILAVN
                     TFITDAQDPNPLIRCMAIRTMSMIRVDKILEYIETPLRRTLHDDNAYVRKTAVICVAK
                     LFQLNKDLCVELGVVEDLVNALDDSNPLVIANATAALIEIHNMDMDAVDLSSLIQSHV
                     SQFLLALNECTEWARIIILGTLSEYSAKDSLEAQDIIDRVTAHLQHVNPAVVLATIKV
                     IVRNLPQIEYSSNSLIMKRLSSAFVSLMSTPPEMQYVALKNIRIILEKYPELLTKELR
                     IFYVKFNDPLYVKLEKIDILVRLVDPSNLKQCTLLLTELKEYAMEYEPEFVSRAIQAL
                     SQLGIKYAQESFVSKVLDILLELLERQDTIKDDCCISLCDLLRHCPGNDKMAKQVCAV
                     FNTWSNPEVLLQSDIAKCNYVWLLGQHPNNFSDLESKINIFIENFVQEEALTQMSLLM
                     TIVRLHATLTGSMLQSVLELATQQTHELDVRDMAMMYWRCLSMPNNESLVNDLCQNKL
                     PMISNTLEKFSPEVLEKLLMELGTISSIYFKPDSNRRKGKKYVQNIVKGKHIEELESM
                     AKNEISSKANDDVLLDFDERDDVTNTNAGMLNTLTTLGDLDDLFDFGPSEDATQINTN
                     DTKAVQGLKELKLGGDSNGISSGGKNNPDVSGGNIVSQDLLDLF"
     gene            complement(<189124..>191442)
                     /gene="OCT1"
                     /locus_tag="YKL134C"
                     /db_xref="GeneID:853724"
     mRNA            complement(<189124..>191442)
                     /gene="OCT1"
                     /locus_tag="YKL134C"
                     /product="Oct1p"
                     /transcript_id="NM_001179700.2"
                     /db_xref="GI:330443645"
                     /db_xref="GeneID:853724"
     CDS             complement(189124..191442)
                     /gene="OCT1"
                     /locus_tag="YKL134C"
                     /EC_number="3.4.24.59"
                     /note="Mitochondrial intermediate peptidase; cleaves
                     destabilizing N-terminal residues of a subset of proteins
                     upon import, after their cleavage by mitochondrial
                     processing peptidase (Mas1p-Mas2p); may contribute to
                     mitochondrial iron homeostasis"
                     /codon_start=1
                     /product="Oct1p"
                     /protein_id="NP_012788.2"
                     /db_xref="GI:330443646"
                     /db_xref="SGD:S000001617"
                     /db_xref="GeneID:853724"
                     /translation="MLRTIILKAGSNASIPSPSRQNKLLRFFATAGAVSRTSPGSIKK
                     IFDDNSYWRNINGQDANNSKISQYLFKKNKTGLFKNPYLTSPDGLRKFSQVSLQQAQE
                     LLDKMRNDFSESGKLTYIMNLDRLSDTLCRVIDLCEFIRSTHPDDAFVRAAQDCHEQM
                     FEFMNVLNTDVSLCNILKSVLNNPEVSSKLSAEELKVGKILLDDFEKSGIYMNPDVRE
                     KFIQLSQEISLVGQEFINHTDYPGSNSVKIPCKDLDNSKVSTFLLKQLNKDVKGQNYK
                     VPTFGYAAYALLKSCENEMVRKKLWTALHSCSDKQVKRLSHLIKLRAILANLMHKTSY
                     AEYQLEGKMAKNPKDVQDFILTLMNNTIEKTANELKFIAELKAKDLKKPLTTNTDEIL
                     KLVRPWDRDYYTGKYFQLNPSNSPNAKEISYYFTLGNVIQGLSDLFQQIYGIRLEPAI
                     TDEGETWSPDVRRLNVISEEEGIIGIIYCDLFERNGKTSNPAHFTVCCSRQIYPSETD
                     FSTIQVGENPDGTYFQLPVISLVCNFSPILIASKKSLCFLQLSEVETLFHEMGHAMHS
                     MLGRTHMQNISGTRCATDFVELPSILMEHFAKDIRILTKIGKHYGTGETIQADMLQRF
                     MKSTNFLQNCETYSQAKMAMLDQSFHDEKIISDIDNFDVVENYQALERRLKVLVDDQS
                     NWCGRFGHLFGYGATYYSYLFDRTIASKIWYALFEDDPYSRKNGDKFKKHLLKWGGLK
                     DPWKCIADVLECPMLEKGGSDAMEFIAQSHKS"
     gene            complement(<191679..>193070)
                     /locus_tag="YKL133C"
                     /db_xref="GeneID:853725"
     mRNA            complement(<191679..>193070)
                     /locus_tag="YKL133C"
                     /product="hypothetical protein"
                     /transcript_id="NM_001179699.2"
                     /db_xref="GI:330443647"
                     /db_xref="GeneID:853725"
     CDS             complement(191679..193070)
                     /locus_tag="YKL133C"
                     /note="hypothetical protein; not required for growth of
                     cells lacking the mitochondrial genome (null mutation does
                     not confer a petite-negative phenotype); YKL133C has a
                     paralog, MGR3, that arose from the whole genome
                     duplication"
                     /codon_start=1
                     /product="hypothetical protein"
                     /protein_id="NP_012789.2"
                     /db_xref="GI:330443648"
                     /db_xref="SGD:S000001616"
                     /db_xref="GeneID:853725"
                     /translation="MWKYLHRSVKNEGTVERLTNLNLFTNHRFKFYSTLKEQSFWRIP
                     FKRRSKLQKWVLSTGIVSFIAFNIWWVYWPHHTFPKPVAKILRKGLHSEIKKEGANYQ
                     KSLEYYLEALEECKAENVDLLSDEYTGIEIKIGEMYEKLHMYNDATALYGDMLKKFYN
                     ELSKTTDKSTKRKFFLLKRDLQILVRFNEINKDSETNATLLIMHLLLAQREFLENSPE
                     FKNVLSKSELLNNQQLDWKNFKGLPFIGKSKPDYQMHLNSKRKQELKIKEPESEQCVF
                     MKELLTARDLYTRYCLNRSNLSGALNSKITTLEWMLLADSPLDDILLAQAELGSIFYL
                     NSEKFEGSLYAIDNEPYKKSEPLELIRSRLQENQNSCLQYSADCYKSIISFANENQYP
                     KVAMESEMDQRILKALSLAHYGIGVINLHKGRLRASKKELKKAIRISEMIRFNELIEE
                     AQRELKKVDGTPI"
     gene            complement(<193574..>194866)
                     /gene="RMA1"
                     /locus_tag="YKL132C"
                     /db_xref="GeneID:853727"
     mRNA            complement(<193574..>194866)
                     /gene="RMA1"
                     /locus_tag="YKL132C"
                     /product="putative tetrahydrofolate synthase"
                     /transcript_id="NM_001179698.1"
                     /db_xref="GI:296146250"
                     /db_xref="GeneID:853727"
     CDS             complement(193574..194866)
                     /gene="RMA1"
                     /locus_tag="YKL132C"
                     /EC_number="6.3.2.17"
                     /note="Putative dihydrofolate synthetase; similar to E.
                     coli folylpolyglutamate synthetase/dihydrofolate
                     synthetase; the authentic, non-tagged protein is detected
                     in highly purified mitochondria in high-throughput
                     studies; RMA1 has a paralog, FOL3, that arose from the
                     whole genome duplication"
                     /codon_start=1
                     /product="putative tetrahydrofolate synthase"
                     /protein_id="NP_012790.1"
                     /db_xref="GI:6322718"
                     /db_xref="SGD:S000001615"
                     /db_xref="GeneID:853727"
                     /translation="MDDISGRQTLPRINRLLEHVGNPQDSLSILHIAGTNGKETVSKF
                     LTSILQHPGQQRQRVLIGRYTTSSLLNAKEEDISINNEAISLIEYSRIEKELIEADSS
                     LKLQCNNLELLTSVALVYFAKKNCQWCIIETGLAGKQDPGSIIAGQSRVCCAITNVGI
                     SDEAFLCKFLSQITESSTNKAIFLLDGSNDEFVRNTITKRCHDVGCPLEITDPSLRDY
                     NVHTDTWGTLEVRLPYSEEEYQIFNLRVAIAVLDFLSKEKKVCISKDQLSQGLISVDW
                     PRSLHRLDYCYESTSGKKIALLLDNANNAKAARNLACHLRTTYGDTPLTFVIAITTGK
                     KVSPLLDPLIRPQDYVIVTRFGSVVGMPWIQSLEPVNLLAFIKNRYTRNVNMQPDLQS
                     VWTFLETSGLKTIVPVIVCGSLYICKELLRLHNCHLPV"
     gene            complement(<195288..>196028)
                     /gene="SHE2"
                     /locus_tag="YKL130C"
                     /db_xref="GeneID:853728"
     mRNA            complement(<195288..>196028)
                     /gene="SHE2"
                     /locus_tag="YKL130C"
                     /product="She2p"
                     /transcript_id="NM_001179696.1"
                     /db_xref="GI:296146251"
                     /db_xref="GeneID:853728"
     CDS             complement(195288..196028)
                     /gene="SHE2"
                     /locus_tag="YKL130C"
                     /note="RNA-binding protein that binds specific mRNAs and
                     interacts with She3p; part of the mRNA localization
                     machinery that restricts accumulation of certain proteins
                     to the bud; binds to ER-derived membranes and targets
                     mRNAs to cortical ER"
                     /codon_start=1
                     /product="She2p"
                     /protein_id="NP_012792.1"
                     /db_xref="GI:6322719"
                     /db_xref="SGD:S000001613"
                     /db_xref="GeneID:853728"
                     /translation="MSKDKDIKVTPGTCELVEQILALLSRYLSSYIHVLNKFISHLRR
                     VATLRFERTTLIKFVKKLRFYNDCVLSYNASEFINEGKNELDPEADSFDKVILPIASM
                     FVKCVETFDLLNYYLTQSLQKEILSKTLNEDLTLTAESILAIDDTYNHFVKFSQWMIE
                     SLRIGSNLLDLEVVQFAIKCADEDGTNIGETDNIFLQEILPVNSEEEFQTLSAAWHSI
                     LDGKLSALDEEFDVVATKWHDKFGKLKN"
     rep_origin      196042..196287
                     /note="ARS1126;
                     Autonomously Replicating Sequence"
                     /db_xref="SGD:S000119036"
     gene            complement(<196349..>200167)
                     /gene="MYO3"
                     /locus_tag="YKL129C"
                     /db_xref="GeneID:853729"
     mRNA            complement(<196349..>200167)
                     /gene="MYO3"
                     /locus_tag="YKL129C"
                     /product="myosin 3"
                     /transcript_id="NM_001179695.2"
                     /db_xref="GI:330443649"
                     /db_xref="GeneID:853729"
     CDS             complement(196349..200167)
                     /gene="MYO3"
                     /locus_tag="YKL129C"
                     /note="One of two type I myosins; localizes to actin
                     cortical patches; deletion of MYO3 has little effect on
                     growth, but myo3 myo5 double deletion causes severe
                     defects in growth and actin cytoskeleton organization;
                     MYO3 has a paralog, MYO5, that arose from the whole genome
                     duplication"
                     /codon_start=1
                     /product="myosin 3"
                     /protein_id="NP_012793.2"
                     /db_xref="GI:330443650"
                     /db_xref="SGD:S000001612"
                     /db_xref="GeneID:853729"
                     /translation="MAVIKKGARRKDVKEPKKRSAKIKKATFDANKKKEVGISDLTLL
                     SKISDESINENLKKRFKNGIIYTYIGHVLISVNPFRDLGIYTNAVLESYKGKNRLEVP
                     PHVFAIAESMYYNLKSYNENQCVIISGESGAGKTEAAKRIMQYIAAASNSHSESIGKI
                     KDMVLATNPLLESFGCAKTLRNNNSSRHGKYLEIKFNSQFEPCAGNITNYLLEKQRVV
                     GQIKNERNFHIFYQFTKGASDTYKQMFGVQMPEQYIYTAAAGCTTADTIDDVKDYEGT
                     LEAMRTIGLVQEEQDQIFRMLAAILWIGNISFIENEEGNAQVGDTSVTDFVAYLLQVD
                     ASLLVKCLVERIMQTSHGMKRGSVYHVPLNPVQATAVRDALAKAIYNNLFDWIVDRVN
                     VSLQAFPGADKSIGILDIYGFEIFEHNSFEQICINYVNEKLQQIFIQLTLKAEQETYE
                     REKIKWTPIKYFDNKVVCDLIEAKNPPGILAAMNDSIATAHADSNAADQAFAQRLNLF
                     NSNPYFELRANKFVIKHYAGDVTYDINGITDKNKDQLQKDLIELIGTTTNTFLSTIFP
                     DDVDKDSKRRPPTAGDKIIKSANELVETLSKAEPSYIRTIKPNQTKSPNDYDDHQVLH
                     QVKYLGLQENVRIRRAGFAYRQTFEKFVERFYLLSPDCSYAGDYTWDGDTLEAVKLIL
                     RDAMIPEKEFQLGVTSVFIKTPESLFALEDMRDKYWYNMAARIQRAWRRFLQRRIDAA
                     IKIQRTIREKKGGNKYVKLRDYGTKLLAGKKERRSMSLLGYRAFMGDYLSCNESKTKG
                     SYIRRQVGIKDKVVFSIKGECLHSKFGRSAQRLKKVFILTKKTFYIIGQTREQNAMKY
                     TQDYKIDVGKIKQVSLTNLQDDWMGVILVNSTQSDPLINTPFKTELMTRLKKLNEKIM
                     IKVGPTIEYHKQPNKLHTVRSKISDSAPKYGDIYKSSTIYVRRGHPANSKSNKKPKNP
                     GGLSGKPIKSKKSKHKSTHKHTHSHRSHRDAAKKQPLPSQKPVNPLSLAATAAQAAYN
                     PKPDKTVPIKSSAIPAAKVSSKHSSKPSSKEKVAVKKASSSHKSSSAKQNQVSMPPSK
                     GVEKNKEPLKETTATATANIPIPPPPPPMGQPKDPKFEAAYDFPGSGSSSELPLKKGD
                     IVFISRDEPSGWSLAKLLDGSKEGWVPTAYMTPYKDTRNTVPVAATGAVNDVTNQKSS
                     QIDNTISSAQEGVQFGSATVGPTSDNQSNPVGTFSDGLASALAARANKMRAESADDDD
                     NDDGDDDDDW"
     gene            complement(<200884..>201771)
                     /gene="PMU1"
                     /locus_tag="YKL128C"
                     /db_xref="GeneID:853730"
     mRNA            complement(<200884..>201771)
                     /gene="PMU1"
                     /locus_tag="YKL128C"
                     /product="Pmu1p"
                     /transcript_id="NM_001179694.1"
                     /db_xref="GI:296146253"
                     /db_xref="GeneID:853730"
     CDS             complement(200884..201771)
                     /gene="PMU1"
                     /locus_tag="YKL128C"
                     /EC_number="5.4.-.-"
                     /note="Putative phosphomutase; contains a region
                     homologous to the active site of phosphomutases;
                     overexpression suppresses the histidine auxotrophy of an
                     ade3 ade16 ade17 triple mutant and the temperature
                     sensitivity of a tps2 mutant"
                     /codon_start=1
                     /product="Pmu1p"
                     /protein_id="NP_012794.1"
                     /db_xref="GI:6322721"
                     /db_xref="SGD:S000001611"
                     /db_xref="GeneID:853730"
                     /translation="MSLRAVPGYFAAYPSEGFQGLDSTKYDHLELINHKNWKELYHAI
                     PRNTKNRHYKLLILARHGQGYHNAAILRYGMEKWDAYWSLLSGDEHGEWLDSKLTPLG
                     KDQVRRTGSNVLLPMAKQLGMLPHVFFSSPMRRCLETFIESWTPVLAETQELPAGTKI
                     STRIIEGLRETLGSHTCDKRVAHSMAVDEYQDFSTESGHTVHWQYVPDYPEDDELWLP
                     DHRETCAEMDKRTLNGLFELFNQLSSEEKFISLTCHSGVIQSVLRNLQHPPIYNLDTG
                     KVVAVVVEVPVNTADRGRL"
     LTR             complement(202644..202983)
                     /note="Ty3 LTR"
                     /db_xref="SGD:S000007054"
     gene            202999..203071
                     /locus_tag="tK(CUU)K"
                     /db_xref="GeneID:853731"
     tRNA            202999..203071
                     /locus_tag="tK(CUU)K"
                     /product="tRNA-Lys"
                     /note="Lysine tRNA (tRNA-Lys), predicted by tRNAscan-SE
                     analysis; a small portion is imported into mitochondria
                     via interaction with mt lysyl-tRNA synthetase Msk1p and is
                     necessary to decode AAG codons at high temperature, when
                     base modification of mt-encoded tRNA-Lys is reduced"
                     /db_xref="SGD:S000006626"
                     /db_xref="GeneID:853731"
     gene            <203541..>205253
                     /gene="PGM1"
                     /locus_tag="YKL127W"
                     /db_xref="GeneID:853732"
     mRNA            <203541..>205253
                     /gene="PGM1"
                     /locus_tag="YKL127W"
                     /product="phosphoglucomutase PGM1"
                     /transcript_id="NM_001179693.1"
                     /db_xref="GI:296146254"
                     /db_xref="GeneID:853732"
     CDS             203541..205253
                     /gene="PGM1"
                     /locus_tag="YKL127W"
                     /EC_number="5.4.2.2"
                     /note="Phosphoglucomutase, minor isoform; catalyzes the
                     conversion from glucose-1-phosphate to
                     glucose-6-phosphate, which is a key step in hexose
                     metabolism; PGM1 has a paralog, PGM2, that arose from the
                     whole genome duplication"
                     /codon_start=1
                     /product="phosphoglucomutase PGM1"
                     /protein_id="NP_012795.1"
                     /db_xref="GI:6322722"
                     /db_xref="SGD:S000001610"
                     /db_xref="GeneID:853732"
                     /translation="MSLLIDSVPTVAYKDQKPGTSGLRKKTKVFMDEPHYTENFIQAT
                     MQSIPNGSEGTTLVVGGDGRFYNDVIMNKIAAVGAANGVRKLVIGQGGLLSTPAASHI
                     IRTYEEKCTGGGIILTASHNPGGPENDLGIKYNLPNGGPAPESVTNAIWEASKKLTHY
                     KIIKNFPKLNLNKLGKNQKYGPLLVDIIDPAKAYVQFLKEIFDFDLIKSFLAKQRKDK
                     GWKLLFDSLNGITGPYGKAIFVDEFGLPAEEVLQNWHPLPDFGGLHPDPNLTYARTLV
                     DRVDREKIAFGAASDGDGDRNMIYGYGPAFVSPGDSVAIIAEYAPEIPYFAKQGIYGL
                     ARSFPTSSAIDRVAAKKGLRCYEVPTGWKFFCALFDAKKLSICGEESFGTGSNHIREK
                     DGLWAIIAWLNILAIYHRRNPEKEASIKTIQDEFWNEYGRTFFTRYDYEHIECEQAEK
                     VVALLSEFVSRPNVCGSHFPADESLTVIDCGDFSYRDLDGSISENQGLFVKFSNGTKF
                     VLRLSGTGSSGATIRLYVEKYTDKKENYGQTADVFLKPVINSIVKFLRFKEILGTDEP
                     TVRT"
     gene            <205707..>207749
                     /gene="YPK1"
                     /locus_tag="YKL126W"
                     /gene_synonym="SLI2"
                     /db_xref="GeneID:853733"
     mRNA            <205707..>207749
                     /gene="YPK1"
                     /locus_tag="YKL126W"
                     /gene_synonym="SLI2"
                     /product="serine/threonine protein kinase YPK1"
                     /transcript_id="NM_001179692.1"
                     /db_xref="GI:296146255"
                     /db_xref="GeneID:853733"
     CDS             205707..207749
                     /gene="YPK1"
                     /locus_tag="YKL126W"
                     /gene_synonym="SLI2"
                     /EC_number="2.7.11.1"
                     /note="Serine/threonine protein kinase; phosphorylates and
                     downregulates flippase activator Fpk1p; inactivates Orm1p
                     and Orm2p (inhibitors of serine:palmitoyl-coenzyme A
                     transferase) by phosphorylation in response to compromised
                     sphingolipid synthesis; mutations affect receptor-mediated
                     endocytosis and sphingolipid-mediated and cell integrity
                     signaling pathways; homolog of mammalian kinase SGK; YPK1
                     has a paralog, YPK2, that arose from the whole genome
                     duplication"
                     /codon_start=1
                     /product="serine/threonine protein kinase YPK1"
                     /protein_id="NP_012796.1"
                     /db_xref="GI:6322723"
                     /db_xref="SGD:S000001609"
                     /db_xref="GeneID:853733"
                     /translation="MYSWKSKFKFGKSKEEKEAKHSGFFHSSKKEEQQNNQATAGEHD
                     ASITRSSLDRKGTINPSNSSVVPVRVSYDASSSTSTVRDSNGGNSENTNSSQNLDETA
                     NIGSTGTPNDATSSSGMMTIKVYNGDDFILPFPITSSEQILNKLLASGVPPPHKEISK
                     EVDALIAQLSRVQIKNQGPADEDLISSESAAKFIPSTIMLPGSSTLNPLLYFTIEFDN
                     TVATIEAEYGTIAKPGFNKISTFDVTRKLPYLKIDVFARIPSILLPSKTWQQEMGLQD
                     EKLQTIFDKINSNQDIHLDSFHLPINLSFDSAASIRLYNHHWITLDNGLGKINISIDY
                     KPSRNKPLSIDDFDLLKVIGKGSFGKVMQVRKKDTQKVYALKAIRKSYIVSKSEVTHT
                     LAERTVLARVDCPFIVPLKFSFQSPEKLYFVLAFINGGELFYHLQKEGRFDLSRARFY
                     TAELLCALDNLHKLDVVYRDLKPENILLDYQGHIALCDFGLCKLNMKDDDKTDTFCGT
                     PEYLAPELLLGLGYTKAVDWWTLGVLLYEMLTGLPPYYDEDVPKMYKKILQEPLVFPD
                     GFDRDAKDLLIGLLSRDPTRRLGYNGADEIRNHPFFSQLSWKRLLMKGYIPPYKPAVS
                     NSMDTSNFDEEFTREKPIDSVVDEYLSESVQKQFGGWTYVGNEQLGSSMVQGRSIR"
     gene            <208247..>210130
                     /gene="RRN3"
                     /locus_tag="YKL125W"
                     /db_xref="GeneID:853734"
     mRNA            <208247..>210130
                     /gene="RRN3"
                     /locus_tag="YKL125W"
                     /product="Rrn3p"
                     /transcript_id="NM_001179691.1"
                     /db_xref="GI:296146256"
                     /db_xref="GeneID:853734"
     CDS             208247..210130
                     /gene="RRN3"
                     /locus_tag="YKL125W"
                     /note="Protein required for transcription of rDNA by RNA
                     polymerase I; transcription factor independent of DNA
                     template; involved in recruitment of RNA polymerase I to
                     rDNA; structure reveals unique HEAT repeat fold and a
                     surface serine patch; phosphorylation of serine patch
                     impairs cell growth and reduces RNA polymerase I binding
                     in vitro and RNA polymerase I recruitment to the rDNA gene
                     in vivo"
                     /codon_start=1
                     /product="Rrn3p"
                     /protein_id="NP_012797.1"
                     /db_xref="GI:6322724"
                     /db_xref="SGD:S000001608"
                     /db_xref="GeneID:853734"
                     /translation="MMAFENTSKRPPQDFVAPIDQKKRKVQFSDSTGLVTLQPEEIKD
                     EVFSAAMYSRFVKSALDDLDKNDSTQIGIIANQVALPSKNPERINDKNLNILLDILSS
                     NINRIESSRGTFLIQSIINFEKWWELPPHTLSKYIYFIKILCSSIPKWWQDVSMILVS
                     CFILPIKQTVCHHDMLKYFLRMIPSSMGFIDTYLAKFFPNKNDTRRKLVNYTSNLLKL
                     RGYCSELGFQIWSLLIEKIISIDVELQNELDELDDDVDDDDLEEVDLEDDDDLDDDSG
                     DDDDENCGNSNEELRSGAADGSQSDSEDMDIIEGMDGTEEYNVELTQGIKELSTKLDS
                     ILTLVSTHVEEQVTPESLESGEGVGVFNTLTTLFKTHVLPTYYTRSIQYIMFHVSQQQ
                     LELMDSFLVTLIDISFAVNEAAEKKIKSLQYLGSYIARAKKLSRTQIIFVASYLTSWL
                     NRYVIEREEEVDQRGGMERFKHFYAAFQALCYIFCFRHNIFRDTDGNWECELDKFFQR
                     MVISKFNPLKFCNENVMLMFARIAQQESVAYCFSIIENNNNERLRGIIGKADSDKKEN
                     SAQANTTSSSWSLATRQQFIDLQSYFPYDPLFLKNYKILMKEYYIEWSEASGEYESDG
                     SDD"
     gene            <210593..>212332
                     /gene="SSH4"
                     /locus_tag="YKL124W"
                     /gene_synonym="MLF4"
                     /db_xref="GeneID:853735"
     mRNA            <210593..>212332
                     /gene="SSH4"
                     /locus_tag="YKL124W"
                     /gene_synonym="MLF4"
                     /product="Ssh4p"
                     /transcript_id="NM_001179690.1"
                     /db_xref="GI:296146257"
                     /db_xref="GeneID:853735"
     CDS             210593..212332
                     /gene="SSH4"
                     /locus_tag="YKL124W"
                     /gene_synonym="MLF4"
                     /note="Specificity factor required for Rsp5p-dependent
                     ubiquitination; also required for sorting of cargo
                     proteins at the multivesicular body; identified as a
                     high-copy suppressor of a SHR3 deletion, increasing
                     steady-state levels of amino acid permeases"
                     /codon_start=1
                     /product="Ssh4p"
                     /protein_id="NP_012798.1"
                     /db_xref="GI:6322725"
                     /db_xref="SGD:S000001607"
                     /db_xref="GeneID:853735"
                     /translation="MYVTFNEALDSSFGNLESPNHDFKVGDPNMVPTPPMDSDSAAIS
                     LAFLISLSITFAILMLILVVIAAYVTFCGDDESEYDEENALGTRTSGTLHSLFGKKHS
                     GILLDSSFASPGGFDDEIVLQERELEELPKMSAYEVELYIRAKEFQMMSPPMVKDFGT
                     YLDSDDQQFIKDRGIQSYFLLPSINDNIDEYGNFLPSFIVQDKLDIQFSKFNKSSSTV
                     MNYPLPHNRKDAVYFEVKIFRHIQKSNSIFSIGLTTVPYPYFRVPGMAKYSIAYESTG
                     KLRINNPFTASTLLPKLEEGDTVGFGYRYKTGTIFITHNGKKLMDVTQNIGIDLFIGI
                     GAFNAAYTRTYTRDGLLEDPDNVSFREALSEGKDIEVAKDLQRVHDPHDESDEMTSDE
                     VELHVNLGQVGFVFIEANVKKYAFGSVYGQIGIPPAYNGTEIKKDTILQKGEELPPRY
                     ADTDNFFGSMKVKEGSSSRITAQTSKPLWSVGTYERISSNFDRENNVYHDSLETDDNN
                     TDNNVNNNDENAGCNENSPLLEDDGNKRPENSNTPREVSDGAINKNPRNKSTKKRQRN
                     RGKSSKKKNRSRK"
     gene            complement(<212495..>212998)
                     /gene="SRP21"
                     /locus_tag="YKL122C"
                     /db_xref="GeneID:853737"
     mRNA            complement(<212495..>212998)
                     /gene="SRP21"
                     /locus_tag="YKL122C"
                     /product="Srp21p"
                     /transcript_id="NM_001179688.1"
                     /db_xref="GI:296146258"
                     /db_xref="GeneID:853737"
     CDS             complement(212495..212998)
                     /gene="SRP21"
                     /locus_tag="YKL122C"
                     /note="Subunit of the signal recognition particle (SRP);
                     SRP functions in protein targeting to the endoplasmic
                     reticulum membrane; not found in mammalian SRP; forms a
                     pre-SRP structure in the nucleolus that is translocated to
                     the cytoplasm"
                     /codon_start=1
                     /product="Srp21p"
                     /protein_id="NP_012800.1"
                     /db_xref="GI:6322727"
                     /db_xref="SGD:S000001605"
                     /db_xref="GeneID:853737"
                     /translation="MSVKPIDNYITNSVRLFEVNPSQTLFSISYKPPTQKTDTKVSFR
                     THNSHLSLNYKFTTNKSKDVSRLLSALGPRGVSITPGKIEKIAQSKKKNNKIKESSKK
                     IKGKSIQDIVGLATLIVNTDVEKSDPAAKKTATEPKQKANAVQNNNGNSAASKKKKNK
                     NKGKKKR"
     rep_origin      213439..213743
                     /note="ARS1127;
                     Autonomously Replicating Sequence"
                     /db_xref="SGD:S000119037"
     gene            <214142..>216700
                     /gene="DGR2"
                     /locus_tag="YKL121W"
                     /db_xref="GeneID:853738"
     mRNA            <214142..>216700
                     /gene="DGR2"
                     /locus_tag="YKL121W"
                     /product="Dgr2p"
                     /transcript_id="NM_001179687.1"
                     /db_xref="GI:296146259"
                     /db_xref="GeneID:853738"
     CDS             214142..216700
                     /gene="DGR2"
                     /locus_tag="YKL121W"
                     /note="hypothetical protein; null mutant is resistant to
                     2-deoxy-D-glucose and displays abnormally elongated buds;
                     DGR2 has a paralog, YMR102C, that arose from the whole
                     genome duplication"
                     /codon_start=1
                     /product="Dgr2p"
                     /protein_id="NP_012801.1"
                     /db_xref="GI:6322728"
                     /db_xref="SGD:S000001604"
                     /db_xref="GeneID:853738"
                     /translation="MFKSKTSTLSYDETPNSNEGDRNATPVNPKEKSQTKHLNIPGDR
                     SRHSSIADSKRSSSRYDGGYSADIIPAQLRFIDNIDYGTRLRKTLHRNSVVSNGYNKL
                     SENDRWYFDLFDRKYFENYLEEPTYIKIFKKKEGLEQFDRMFLAQELKIPDVYKSTTY
                     QGEPAVANSELFKNSICCCTFSHDGKYMVIGCKDGSLHLWKVINSPVKRSEMGRSEKS
                     VSASRANSLKIQRHLASISSHNGSISSNDLKPSDQFEGPSKQLHLYAPVFYSDVFRVF
                     MEHALDILDANWSKNGFLITASMDKTAKLWHPERKYSLKTFVHPDFVTSAIFFPNDDR
                     FIITGCLDHRCRLWSILDNEVSYAFDCKDLITSLTLSPPGGEYTIIGTFNGYIYVLLT
                     HGLKFVSSFHVSDKSTQGTTKNSFHPSSEYGKVQHGPRITGLQCFFSKVDKNLRLIVT
                     TNDSKIQIFDLNEKKPLELFKGFQSGSSRHRGQFLMMKNEPVVFTGSDDHWFYTWKMQ
                     SFNLSAEMNCTAPHRKKRLSGSMSLKGLLRIVSNKSTNDECLTETSNQSSSHTFTNSS
                     KNVLQTQTVGSQAIKNNHYISFHAHNSPVTCASIAPDVAIKNLSLSNDLIFELTSQYF
                     KEMGQNYSESKETCDNKPNHPVTETGGFSSNLSNVVNNVGTILITTDSQGLIRVFRTD
                     ILPEIRKKIIEKFHEYNLFHLEAAGKINNHNNDSILENRMDERSSTEDNEFSTTPPSN
                     THNSRPSHDFCELHPNNSPVISGMPSRASAIFKNSIFNKSNGSFISLKSRSESTSSTV
                     FGPHDIPRVSTTYPKLKCDVCNGSNFECASKNPIAGGDSGFTCADCGTILNNFR"
     gene            <217344..>218318
                     /gene="OAC1"
                     /locus_tag="YKL120W"
                     /db_xref="GeneID:853739"
     mRNA            <217344..>218318
                     /gene="OAC1"
                     /locus_tag="YKL120W"
                     /product="Oac1p"
                     /transcript_id="NM_001179686.1"
                     /db_xref="GI:296146260"
                     /db_xref="GeneID:853739"
     CDS             217344..218318
                     /gene="OAC1"
                     /locus_tag="YKL120W"
                     /note="Mitochondrial inner membrane transporter;
                     transports oxaloacetate, sulfate, thiosulfate, and
                     isopropylmalate; member of the mitochondrial carrier
                     family"
                     /codon_start=1
                     /product="Oac1p"
                     /protein_id="NP_012802.1"
                     /db_xref="GI:6322729"
                     /db_xref="SGD:S000001603"
                     /db_xref="GeneID:853739"
                     /translation="MSSDNSKQDKQIEKTAAQKISKFGSFVAGGLAACIAVTVTNPIE
                     LIKIRMQLQGEMSASAAKVYKNPIQGMAVIFKNEGIKGLQKGLNAAYIYQIGLNGSRL
                     GFYEPIRSSLNQLFFPDQEPHKVQSVGVNVFSGAASGIIGAVIGSPLFLVKTRLQSYS
                     EFIKIGEQTHYTGVWNGLVTIFKTEGVKGLFRGIDAAILRTGAGSSVQLPIYNTAKNI
                     LVKNDLMKDGPALHLTASTISGLGVAVVMNPWDVILTRIYNQKGDLYKGPIDCLVKTV
                     RIEGVTALYKGFAAQVFRIAPHTIMCLTFMEQTMKLVYSIESRVLGHN"
     gene            complement(<218570..>219217)
                     /gene="VPH2"
                     /locus_tag="YKL119C"
                     /gene_synonym="CLS10; VMA12"
                     /db_xref="GeneID:853741"
     mRNA            complement(<218570..>219217)
                     /gene="VPH2"
                     /locus_tag="YKL119C"
                     /gene_synonym="CLS10; VMA12"
                     /product="Vph2p"
                     /transcript_id="NM_001179685.1"
                     /db_xref="GI:296146261"
                     /db_xref="GeneID:853741"
     CDS             complement(218570..219217)
                     /gene="VPH2"
                     /locus_tag="YKL119C"
                     /gene_synonym="CLS10; VMA12"
                     /note="Integral membrane protein required for V-ATPase
                     function; not an actual component of the vacuolar
                     H+-ATPase (V-ATPase) complex; functions in the assembly of
                     the V-ATPase; localized to the endoplasmic reticulum (ER);
                     involved in methionine restriction extension of
                     chronological lifespan in an autophagy-dependent manner"
                     /codon_start=1
                     /product="Vph2p"
                     /protein_id="NP_012803.1"
                     /db_xref="GI:6322731"
                     /db_xref="SGD:S000001602"
                     /db_xref="GeneID:853741"
                     /translation="MFEIKLNDRITEFLRKFKNSAKSNEGIDEDIDLFLKRHAIPMQS
                     LLFYVKEYRKDSDLQCSIKELLKPLEFEFKPKAVRGLHYSEDFKKKLEFLKYQEQELE
                     YQSMVKRSKSVFSLQEDDELTPSQINKQIKEQVTTVFNVLVSVISVVVAIWYWTGSST
                     NFPVHVRLLLCLFFGILVLVADVVVYNSYLKKLEEAKVKEKTKVEKKKVLSKITL"
     LTR             complement(219395..219723)
                     /note="Ty1 LTR"
                     /db_xref="SGD:S000007051"
     gene            219895..219967
                     /locus_tag="tA(AGC)K1"
                     /db_xref="GeneID:853742"
     tRNA            219895..219967
                     /locus_tag="tA(AGC)K1"
                     /product="tRNA-Ala"
                     /note="Alanine tRNA (tRNA-Ala), predicted by tRNAscan-SE
                     analysis; one of 11 nuclear tRNA genes containing the
                     tDNA-anticodon AGC (converted to IGC in the mature tRNA),
                     decodes GCU and GCC codons into alanine, one of 16 nuclear
                     tRNAs for alanine"
                     /db_xref="SGD:S000006515"
                     /db_xref="GeneID:853742"
     gene            <220324..>220974
                     /gene="SBA1"
                     /locus_tag="YKL117W"
                     /gene_synonym="CST18"
                     /db_xref="GeneID:853743"
     mRNA            <220324..>220974
                     /gene="SBA1"
                     /locus_tag="YKL117W"
                     /gene_synonym="CST18"
                     /product="Sba1p"
                     /transcript_id="NM_001179683.1"
                     /db_xref="GI:296146262"
                     /db_xref="GeneID:853743"
     CDS             220324..220974
                     /gene="SBA1"
                     /locus_tag="YKL117W"
                     /gene_synonym="CST18"
                     /note="Co-chaperone that binds and regulates Hsp90 family
                     chaperones; plays a role in determining prion variants;
                     important for pp60v-src activity in yeast; homologous to
                     the mammalian p23 proteins, and like p23 can regulate
                     telomerase activity; protein abundance increases in
                     response to DNA replication stress"
                     /codon_start=1
                     /product="Sba1p"
                     /protein_id="NP_012805.1"
                     /db_xref="GI:6322732"
                     /db_xref="SGD:S000001600"
                     /db_xref="GeneID:853743"
                     /translation="MSDKVINPQVAWAQRSSTTDPERNYVLITVSIADCDAPELTIKP
                     SYIELKAQSKPHVGDENVHHYQLHIDLYKEIIPEKTMHKVANGQHYFLKLYKKDLESE
                     YWPRLTKEKVKYPYIKTDFDKWVDEDEQDEVEAEGNDAAQGMDFSQMMGGAGGAGGAG
                     GMDFSQMMGGAGGAGSPDMAQLQQLLAQSGGNLDMGDFKENDEEDEEEEIEPEVKA"
     gene            complement(<221344..>222900)
                     /gene="PRR1"
                     /locus_tag="YKL116C"
                     /db_xref="GeneID:853744"
     mRNA            complement(<221344..>222900)
                     /gene="PRR1"
                     /locus_tag="YKL116C"
                     /product="serine/threonine protein kinase PRR1"
                     /transcript_id="NM_001179682.1"
                     /db_xref="GI:296146263"
                     /db_xref="GeneID:853744"
     CDS             complement(221344..222900)
                     /gene="PRR1"
                     /locus_tag="YKL116C"
                     /EC_number="2.7.11.1"
                     /note="Serine/threonine protein kinase; inhibits pheromone
                     induced signaling downstream of MAPK, possibly at the
                     level of the Ste12p transcription factor"
                     /codon_start=1
                     /product="serine/threonine protein kinase PRR1"
                     /protein_id="NP_012806.1"
                     /db_xref="GI:6322733"
                     /db_xref="SGD:S000001599"
                     /db_xref="GeneID:853744"
                     /translation="MDEYSSIYSQPKTPRLKQEGFPDSIGDQHEKALIDENGEEDKKM
                     ASTEGTTGDSRSTPLTVSIPTFENVQALPTPMTYTPLSPGNLSMSPIDQSSLNIPKRR
                     SHARLLDDMLSVTQPNQRVVSELIAPANLSPQRVVSLPTVTEEALVNDSVDSDNYTKE
                     PYFPESSSSTEKCDDDIFQGFLLDHWDRPLLWKKVRPIGSGNFSTVLLYELMDQSNPK
                     LKQVAVKRLKYPEELSNVEQINTSLRYKETLSRLENSLTRELQVLKSLNHPCIVKLLG
                     INNPIFVTSKKPLCDLIIKTPRALPPCDMIMSYCPAGDLLAAVMARNGRLEAWLIQRI
                     FTEVVLAVKYLHENSIIHRDLKLENILLKYSFDDINSFRDSPIYCKQNFIELADFGLC
                     KKIENNEMCTARCGSEDYVSPEILMGVPYDGHLSDTWALGVILYSLFEDRLPFDPPPN
                     ASARQRSRATSHRIARFDWRWYRLSDYKTNVGKQIVENTLTRKNQRWSINEIYESPFV
                     KTIADTLSFS"
     gene            complement(<223352..>224455)
                     /gene="APN1"
                     /locus_tag="YKL114C"
                     /db_xref="GeneID:853746"
     mRNA            complement(<223352..>224455)
                     /gene="APN1"
                     /locus_tag="YKL114C"
                     /product="DNA-(apurinic or apyrimidinic site) lyase APN1"
                     /transcript_id="NM_001179680.1"
                     /db_xref="GI:296146264"
                     /db_xref="GeneID:853746"
     CDS             complement(223352..224455)
                     /gene="APN1"
                     /locus_tag="YKL114C"
                     /EC_number="4.2.99.18"
                     /note="Major apurinic/apyrimidinic endonuclease; 3'-repair
                     diesterase; involved in repair of DNA damage by oxidation
                     and alkylating agents; also functions as a 3'-5'
                     exonuclease to repair 7,8-dihydro-8-oxodeoxyguanosine;
                     genetically interacts with NTG1 to maintain mitochondrial
                     genome integrity"
                     /codon_start=1
                     /product="DNA-(apurinic or apyrimidinic site) lyase APN1"
                     /protein_id="NP_012808.1"
                     /db_xref="GI:6322735"
                     /db_xref="SGD:S000001597"
                     /db_xref="GeneID:853746"
                     /translation="MPSTPSFVRSAVSKYKFGAHMSGAGGISNSVTNAFNTGCNSFAM
                     FLKSPRKWVSPQYTQEEIDKFKKNCATYNYNPLTDVLPHGQYFINLANPDREKAEKSY
                     ESFMDDLNRCEQLGIGLYNLHPGSTLKGDHQLQLKQLASYLNKAIKETKFVKIVLENM
                     AGTGNLVGSSLVDLKEVIGMIEDKSRIGVCIDTCHTFAAGYDISTTETFNNFWKEFND
                     VIGFKYLSAVHLNDSKAPLGANRDLHERLGQGYLGIDVFRMIAHSEYLQGIPIVLETP
                     YENDEGYGNEIKLMEWLESKSESELLEDKEYKEKNDTLQKLGAKSRKEQLDKFEVKQK
                     KRAGGTKRKKATAEPSDNDILSQMTKKRKTKKE"
     gene            complement(<224727..>225875)
                     /gene="RAD27"
                     /locus_tag="YKL113C"
                     /gene_synonym="ERC11; FEN1; RTH1"
                     /db_xref="GeneID:853747"
     mRNA            complement(<224727..>225875)
                     /gene="RAD27"
                     /locus_tag="YKL113C"
                     /gene_synonym="ERC11; FEN1; RTH1"
                     /product="multifunctional nuclease RAD27"
                     /transcript_id="NM_001179679.1"
                     /db_xref="GI:296146265"
                     /db_xref="GeneID:853747"
     CDS             complement(224727..225875)
                     /gene="RAD27"
                     /locus_tag="YKL113C"
                     /gene_synonym="ERC11; FEN1; RTH1"
                     /EC_number="3.1.-.-"
                     /note="5' to 3' exonuclease, 5' flap endonuclease;
                     required for Okazaki fragment processing and maturation,
                     for long-patch base-excision repair and large loop repair
                     (LLR), ribonucleotide excision repair; member of the S.
                     pombe RAD2/FEN1 family; relocalizes to the cytosol in
                     response to hypoxia"
                     /codon_start=1
                     /product="multifunctional nuclease RAD27"
                     /protein_id="NP_012809.1"
                     /db_xref="GI:6322736"
                     /db_xref="SGD:S000001596"
                     /db_xref="GeneID:853747"
                     /translation="MGIKGLNAIISEHVPSAIRKSDIKSFFGRKVAIDASMSLYQFLI
                     AVRQQDGGQLTNEAGETTSHLMGMFYRTLRMIDNGIKPCYVFDGKPPDLKSHELTKRS
                     SRRVETEKKLAEATTELEKMKQERRLVKVSKEHNEEAQKLLGLMGIPYIIAPTEAEAQ
                     CAELAKKGKVYAAASEDMDTLCYRTPFLLRHLTFSEAKKEPIHEIDTELVLRGLDLTI
                     EQFVDLCIMLGCDYCESIRGVGPVTALKLIKTHGSIEKIVEFIESGESNNTKWKIPED
                     WPYKQARMLFLDPEVIDGNEINLKWSPPKEKELIEYLCDDKKFSEERVKSGISRLKKG
                     LKSGIQGRLDGFFQVVPKTKEQLAAAAKRAQENKKLNKNKNKVTKGRR"
     gene            <226570..>228765
                     /gene="ABF1"
                     /locus_tag="YKL112W"
                     /gene_synonym="BAF1; OBF1; REB2; SBF1"
                     /db_xref="GeneID:853748"
     mRNA            <226570..>228765
                     /gene="ABF1"
                     /locus_tag="YKL112W"
                     /gene_synonym="BAF1; OBF1; REB2; SBF1"
                     /product="DNA-binding protein ABF1"
                     /transcript_id="NM_001179678.1"
                     /db_xref="GI:296146266"
                     /db_xref="GeneID:853748"
     CDS             226570..228765
                     /gene="ABF1"
                     /locus_tag="YKL112W"
                     /gene_synonym="BAF1; OBF1; REB2; SBF1"
                     /note="DNA binding protein with possible
                     chromatin-reorganizing activity; involved in
                     transcriptional activation, gene silencing, and DNA
                     replication and repair"
                     /codon_start=1
                     /product="DNA-binding protein ABF1"
                     /protein_id="NP_012810.1"
                     /db_xref="GI:6322737"
                     /db_xref="SGD:S000001595"
                     /db_xref="GeneID:853748"
                     /translation="MDKLVVNYYEYKHPIINKDLAIGAHGGKKFPTLGAWYDVINEYE
                     FQTRCPIILKNSHRNKHFTFACHLKNCPFKVLLSYAGNAASSETSSPSANNNTNPPGT
                     PDHIHHHSNNMNNEDNDNNNGSNNKVSNDSKLDFVTDDLEYHLANTHPDDTNDKVESR
                     SNEVNGNNDDDADANNIFKQQGVTIKNDTEDDSINKASIDRGLDDESGPTHGNDSGNH
                     RHNEEDDVHTQMTKNYSDVVNDEDINVAIANAVANVDSQSNNKHDGKDDDATNNNDGQ
                     DNNTNNDHNNNSNINNNNVGSHGISSHSPSSIRDTSMNLDVFNSATDDIPGPFVVTKI
                     EPYHSHPLEDNLSLGKFILTKIPKILQNDLKFDQILESSYNNSNHTVSKFKVSHYVEE
                     SGLLDILMQRYGLTAEDFEKRLLSQIARRITTYKARFVLKKKKMGEYNDLQPSSSSNN
                     NNNNDGELSGTNLRSNSIDYAKHQEISSAGTSSNTTKNVNNNKNDSNDDNNGNNNNDA
                     SNLMESVLDKTSSHRYQPKKMPSVNKWSKPDQITHSDVSMVGLDESNDGGNENVHPTL
                     AEVDAQEARETAQLAIDKINSYKRSIDDKNGDGHNNSSRNVVDENLINDMDSEDAHKS
                     KRQHLSDITLEERNEDDKLPHEVAEQLRLLSSHLKEVENLHQNNDDDVDDVMVDVDVE
                     SQYNKNTTHHNNHHSQPHHDEEDVAGLIGKADDEEDLSDENIQPELRGQ"
     gene            complement(<228939..>229880)
                     /gene="KTI12"
                     /locus_tag="YKL110C"
                     /gene_synonym="TOT4"
                     /db_xref="GeneID:853750"
     mRNA            complement(<228939..>229880)
                     /gene="KTI12"
                     /locus_tag="YKL110C"
                     /gene_synonym="TOT4"
                     /product="Kti12p"
                     /transcript_id="NM_001179676.1"
                     /db_xref="GI:296146267"
                     /db_xref="GeneID:853750"
     CDS             complement(228939..229880)
                     /gene="KTI12"
                     /locus_tag="YKL110C"
                     /gene_synonym="TOT4"
                     /note="Protein that plays a role in modification of tRNA
                     wobble nucleosides; protein plays role in tRNA wobble
                     nucleoside modification with Elongator complex; involved
                     in sensitivity to G1 arrest induced by zymocin; interacts
                     with chromatin throughout the genome; also interacts with
                     Cdc19p"
                     /codon_start=1
                     /product="Kti12p"
                     /protein_id="NP_012812.1"
                     /db_xref="GI:6322739"
                     /db_xref="SGD:S000001593"
                     /db_xref="GeneID:853750"
                     /translation="MPLVLFTGYPCSGKTTLAKHLVQLLQSKIDATPSLSKYSITYHS
                     DESLGIKHSDYITSQDERKLRSEIISAVKRDLSKNKIVIVDSLNYIKGFRYQLHCEVK
                     NLSTTFCVIQTLCPPETIFEWNKTSNPNPWEPELLNQLIQRYEEPNSSNRWDSPLFAI
                     LTPQDNITDYIDDICKVVFQTSKSAKNSGHNDPLSKGLQKPNSATVLKPASQSNFIQV
                     LDIETSKIIKTIMNHIKSLTSIGGVSNGTRVIVSEGITDINDDGCFFVDLPIGNVVTL
                     AQLQRLKRQFINFNKLRDIDQDRIGPLFADYLNKNLN"
     gene            <232227..>233891
                     /gene="HAP4"
                     /locus_tag="YKL109W"
                     /db_xref="GeneID:853751"
     mRNA            <232227..>233891
                     /gene="HAP4"
                     /locus_tag="YKL109W"
                     /product="transcription factor HAP4"
                     /transcript_id="NM_001179675.1"
                     /db_xref="GI:296146268"
                     /db_xref="GeneID:853751"
     CDS             232227..233891
                     /gene="HAP4"
                     /locus_tag="YKL109W"
                     /note="Transcription factor; subunit of the
                     heme-activated, glucose-repressed Hap2p/3p/4p/5p
                     CCAAT-binding complex, a transcriptional activator and
                     global regulator of respiratory gene expression; provides
                     the principal activation function of the complex; involved
                     in diauxic shift"
                     /codon_start=1
                     /product="transcription factor HAP4"
                     /protein_id="NP_012813.1"
                     /db_xref="GI:6322740"
                     /db_xref="SGD:S000001592"
                     /db_xref="GeneID:853751"
                     /translation="MTAKTFLLQASASRPRSNHFKNEHNNIPLAPVPIAPNTNHHNNS
                     SLEFENDGSKKKKKSSLVVRTSKHWVLPPRPRPGRRSSSHNTLPANNTNNILNVGPNS
                     RNSSNNNNNNNIISNRKQASKEKRKIPRHIQTIDEKLINDSNYLAFLKFDDLENEKFH
                     SSASSISSPSYSSPSFSSYRNRKKSEFMDDESCTDVETIAAHNSLLTKNHHIDSSSNV
                     HAPPTKKSKLNDFDLLSLSSTSSSATPVPQLTKDLNMNLNFHKIPHKASFPDSPADFS
                     PADSVSLIRNHSLPTNLQVKDKIEDLNEIKFFNDFEKLEFFNKYAKVNTNNDVNENND
                     LWNSYLQSMDDTTGKNSGNYQQVDNDDNMSLLNLPILEETVSSGQDDKVEPDEEDIWN
                     YLPSSSSQQEDSSRALKKNTNSEKANIQAKNDETYLFLQDQDESADSHHHDELGSEIT
                     LADNKFSYLPPTLEELMEEQDCNNGRSFKNFMFSNDTGIDGSAGTDDDYTKVLKSKKI
                     STSKSNANLYDLNDNNNDATATNELDQSSFIDDLDEDVDFLKVQVF"
     gene            <234426..>235787
                     /gene="SLD2"
                     /locus_tag="YKL108W"
                     /gene_synonym="DRC1"
                     /db_xref="GeneID:853752"
     mRNA            <234426..>235787
                     /gene="SLD2"
                     /locus_tag="YKL108W"
                     /gene_synonym="DRC1"
                     /product="Sld2p"
                     /transcript_id="NM_001179674.1"
                     /db_xref="GI:296146269"
                     /db_xref="GeneID:853752"
     CDS             234426..235787
                     /gene="SLD2"
                     /locus_tag="YKL108W"
                     /gene_synonym="DRC1"
                     /note="Single-stranded DNA origin-binding and annealing
                     protein; required for initiation of DNA replication;
                     phosphorylated in S phase by cyclin-dependent kinases
                     (Cdks), promoting origin binding, DNA replication and
                     Dpb11p complex formation; component of the preloading
                     complex; binds the Mcm2-7p complex to prevent
                     inappropriate Mcm2-7p interaction with the GINS complex in
                     G1; required for S phase checkpoint; relative distribution
                     to the nucleus increases upon DNA replication stress"
                     /codon_start=1
                     /product="Sld2p"
                     /protein_id="NP_012814.1"
                     /db_xref="GI:6322741"
                     /db_xref="SGD:S000001591"
                     /db_xref="GeneID:853752"
                     /translation="MYSFELDKLKIELKTWEHDFIDKNKREPTRDDIKSLRTVRQMYK
                     QYSTLKKKQSLQRQKVDTQESVELPAHKKDHDEVVEIGPTPQVYGKAISIFDMNLSPI
                     KPIYMTFTNNIDVNNDNSKTISNESSPRKTILLKSSPADRTLVAEPISSVKRQLNFQM
                     LNASSTRTPTSSPCKNRNGKLVEIKKCSPTINPPLESGKPSGYYGPNSPLKLDEENIH
                     LNISLNSSTKRRLQIAYPSLQKTPSKDQADISTSFSPSPLIRRPLTKSLIELAREHTE
                     IVKEFGVLQEEDIEEEEEGEEGENGYDEKNHEDDFGLEDELIRPKVVKDIFQEDDDND
                     DSQAREDTFIRKRPKRRKVIRRLRDNDPETETAGFERDVHKELVKLKRRKVAEFLGST
                     SQISDTEFEHDPEASSGVVSSEQKPTAKRKGRKKYNLVSNNFRRLKLPKKNRFSNGRW
                     GRR"
     gene            <236141..>237070
                     /locus_tag="YKL107W"
                     /db_xref="GeneID:853753"
     mRNA            <236141..>237070
                     /locus_tag="YKL107W"
                     /product="putative short-chain dehydrogenase/reductase"
                     /transcript_id="NM_001179673.1"
                     /db_xref="GI:296146270"
                     /db_xref="GeneID:853753"
     CDS             236141..237070
                     /locus_tag="YKL107W"
                     /EC_number="1.-.-.-"
                     /note="Putative short-chain dehydrogenase/reductase;
                     proposed to be a palmitoylated membrane protein"
                     /codon_start=1
                     /product="putative short-chain dehydrogenase/reductase"
                     /protein_id="NP_012815.1"
                     /db_xref="GI:6322742"
                     /db_xref="SGD:S000001590"
                     /db_xref="GeneID:853753"
                     /translation="MFWKKDPTVSWERKNINDIDFSRFNVAIIGGTGGLGRAISRELA
                     QRNARVTVVGQTFRDEDLKDKINFVKADLSLVSECKRISHSDEIPYEELTHLIFTTGI
                     FASRQRQATSEGLEKDMAVSYLSRYIIFHDVAKRLGISRTKKDDLPKVFIAGFPGNGQ
                     VGDPDDLNSDEKKYSAYATHMNTVAANESLVIDAKDRYTNIDTFGLNPGLIKTNIRNN
                     LLGSDTYLSRITEWIISWTCQSAETYAKTICTLIASPAIESRSGTMFSNKGDAILPSP
                     GLTKDVVEKFMENSELLVEKALRNQSPFTSSNE"
     gene            complement(<237147..>237266)
                     /locus_tag="YKL106C-A"
                     /db_xref="GeneID:853754"
     mRNA            complement(<237147..>237266)
                     /locus_tag="YKL106C-A"
                     /product="hypothetical protein"
                     /transcript_id="NM_001184482.1"
                     /db_xref="GI:296146271"
                     /db_xref="GeneID:853754"
     CDS             complement(237147..237266)
                     /locus_tag="YKL106C-A"
                     /note="hypothetical protein; identified by homology to
                     uncharacterized proteins in other fungi"
                     /codon_start=1
                     /product="hypothetical protein"
                     /protein_id="NP_076898.1"
                     /db_xref="GI:13129176"
                     /db_xref="SGD:S000007616"
                     /db_xref="GeneID:853754"
                     /translation="MPFPSILHLTIGRYASYDSNNHMRRRAKLMEAIFRIRTI"
     gene            <237536..>238891
                     /gene="AAT1"
                     /locus_tag="YKL106W"
                     /db_xref="GeneID:853755"
     mRNA            <237536..>238891
                     /gene="AAT1"
                     /locus_tag="YKL106W"
                     /product="aspartate transaminase AAT1"
                     /transcript_id="NM_001179672.1"
                     /db_xref="GI:296146272"
                     /db_xref="GeneID:853755"
     CDS             237536..238891
                     /gene="AAT1"
                     /locus_tag="YKL106W"
                     /EC_number="2.6.1.1"
                     /note="Mitochondrial aspartate aminotransferase; catalyzes
                     the conversion of oxaloacetate to aspartate in aspartate
                     and asparagine biosynthesis"
                     /codon_start=1
                     /product="aspartate transaminase AAT1"
                     /protein_id="NP_012816.1"
                     /db_xref="GI:6322743"
                     /db_xref="SGD:S000001589"
                     /db_xref="GeneID:853755"
                     /translation="MLRTRLTNCSLWRPYYTSSLSRVPRAPPDKVLGLSEHFKKVKNV
                     NKIDLTVGIYKDGWGKVTTFPSVAKAQKLIESHLELNKNLSYLPITGSKEFQENVMKF
                     LFKESCPQFGPFYLAHDRISFVQTLSGTGALAVAAKFLALFISRDIWIPDPSWANHKN
                     IFQNNGFENIYRYSYYKDGQIDIDGWIEQLKTFAYNNQQENNKNPPCIILHACCHNPT
                     GLDPTKEQWEKIIDTIYELKMVPIVDMAYQGLESGNLLKDAYLLRLCLNVNKYPNWSN
                     GIFLCQSFAKNMGLYGERVGSLSVITPATANNGKFNPLQQKNSLQQNIDSQLKKIVRG
                     MYSSPPGYGSRVVNVVLSDFKLKQQWFKDVDFMVQRLHHVRQEMFDRLGWPDLVNFAQ
                     QHGMFYYTRFSPKQVEILRNNYFVYLTGDGRLSLSGVNDSNVDYLCESLEAVSKMDKL
                     A"
     gene            complement(<239185..>242583)
                     /gene="SEG2"
                     /locus_tag="YKL105C"
                     /db_xref="GeneID:853756"
     mRNA            complement(<239185..>242583)
                     /gene="SEG2"
                     /locus_tag="YKL105C"
                     /product="Seg2p"
                     /transcript_id="NM_001179671.1"
                     /db_xref="GI:296146273"
                     /db_xref="GeneID:853756"
     CDS             complement(239185..242583)
                     /gene="SEG2"
                     /locus_tag="YKL105C"
                     /note="Eisosome component; likely plays only minor role in
                     eisosome assembly; shown to interact with Seg1p; similar
                     to A. gossypii SEG gene which is important for stabilizing
                     eisosomes; SEG2 has a paralog, SEG1, that arose from the
                     whole genome duplication"
                     /codon_start=1
                     /product="Seg2p"
                     /protein_id="NP_012817.1"
                     /db_xref="GI:6322744"
                     /db_xref="SGD:S000001588"
                     /db_xref="GeneID:853756"
                     /translation="MIQESSPDALAAAAAIGNALSYNGRTVDKSKIPQYNQSFTSRTT
                     SIAGINRYTMLSNSRTNSRMLLMNGNVRQYSKRTSSLPNQGHKNTSNNSAGRRQHRAH
                     EDAETTFREFGGKQSSKVLNISSSTGQNSKSRTTSLGNSGSTIRTIKKYIPGPRGLMA
                     VEVPVEVEPPRYSLSNRSNQRGGRAYSLPTRNNKTSLMHRNKTTKKAGSQEKKSESGG
                     KSKNDYHGKVLSKMHTTSLKQRHNNVPLIPTTMNEETEQELQEDLHDPLEFKPMIISD
                     DENSFIEPSVLDRSIPKKDKSGLSGREKKEEIETLLKEVHSLEEKISNIEIAKLNEEE
                     REQSLILELRKVKLDEERRMELLKRELNIVKENADLEAQELKLIESKRKQHFHKGQEV
                     ASEVKSITIRQPTLSEPKPAYVPPEDVEKEPSTLSNQTQNIENAENIDSVDAEGNLVD
                     PILLGSLNNSNFHMNSDNEVRCIADSNSLTGSELSDYNYIEGSATDLRATAKTSVESE
                     IGGNQVGLKIPQDDDSEKQEERTKGKKSGLVDTNCFLVQKEDQEEALSDNEPESSEKF
                     PSTSGIENVKLEDETGSVMDKNNGPNNDKDDDDDKDNDNDDDDDKDDDVNDDDKDENV
                     DDDENVDDDDDDDDDDDDEYHDSYDVIMRDPVQIEQDISDVPSLKHPSEYSTETEDNK
                     KKEQNSENAEVSQSGTNMAKYLRGANPYLTNTSSDTFSLDSENVNSKSSTDTTRVAPD
                     LLKSSLQPQLRSDLKQSAVPSSTSSSIYSIETSPNIDSSTGKTASNTKTNSHGPPTSI
                     SKQKYDQSSSHQIPVMSPKRLDDKRKITNRSCLRTLRGSSNEATLSHNIVYPASDSSS
                     SPPYHSKKPSNPPSSGNLASHEASKCFPKAPQASTTSRRLPDHVPLYIDKNNSALYPK
                     EPPARKSSFEKERPAKDNLGFRSMSLREPLITKNATATAAENLDVEEKKEKGGHVSRK
                     SWTFGLPSPLKRRTSHSTHTTNETEIVNPMTNFKNKTNENDMPILANKKSCNNDDSSP
                     YTASSMNTNDVSEAGTEGHRFSLFGNKSQLSNRNISGGTATLESSNPDLPTALPLSVP
                     VTIIDKNGEIHKLHNDDAAIKDKSHDRHGHSKFGRKLKKIFGRK"
     gene            complement(<243220..>245373)
                     /gene="GFA1"
                     /locus_tag="YKL104C"
                     /db_xref="GeneID:853757"
     mRNA            complement(<243220..>245373)
                     /gene="GFA1"
                     /locus_tag="YKL104C"
                     /product="glutamine--fructose-6-phosphate transaminase
                     (isomerizing) GFA1"
                     /transcript_id="NM_001179670.1"
                     /db_xref="GI:296146274"
                     /db_xref="GeneID:853757"
     CDS             complement(243220..245373)
                     /gene="GFA1"
                     /locus_tag="YKL104C"
                     /EC_number="2.6.1.16"
                     /note="Glutamine-fructose-6-phosphate amidotransferase;
                     catalyzes the formation of glucosamine-6-P and glutamate
                     from fructose-6-P and glutamine in the first step of
                     chitin biosynthesis; GFA1 has a paralogous region,
                     comprising ORFs YMR084W-YMR085W, that arose from the whole
                     genome duplication"
                     /codon_start=1
                     /product="glutamine--fructose-6-phosphate transaminase
                     (isomerizing) GFA1"
                     /protein_id="NP_012818.1"
                     /db_xref="GI:6322745"
                     /db_xref="SGD:S000001587"
                     /db_xref="GeneID:853757"
                     /translation="MCGIFGYCNYLVERSRGEIIDTLVDGLQRLEYRGYDSTGIAIDG
                     DEADSTFIYKQIGKVSALKEEITKQNPNRDVTFVSHCGIAHTRWATHGRPEQVNCHPQ
                     RSDPEDQFVVVHNGIITNFRELKTLLINKGYKFESDTDTECIAKLYLHLYNTNLQNGH
                     DLDFHELTKLVLLELEGSYGLLCKSCHYPNEVIATRKGSPLLIGVKSEKKLKVDFVDV
                     EFPEENAGQPEIPLKSNNKSFGLGPKKAREFEAGSQNANLLPIAANEFNLRHSQSRAF
                     LSEDGSPTPVEFFVSSDAASVVKHTKKVLFLEDDDLAHIYDGELHIHRSRREVGASMT
                     RSIQTLEMELAQIMKGPYDHFMQKEIYEQPESTFNTMRGRIDYENNKVILGGLKAWLP
                     VVRRARRLIMIACGTSYHSCLATRAIFEELSDIPVSVELASDFLDRKCPVFRDDVCVF
                     VSQSGETADTMLALNYCLERGALTVGIVNSVGSSISRVTHCGVHINAGPEIGVASTKA
                     YTSQYIALVMFALSLSDDRVSKIDRRIEIIQGLKLIPGQIKQVLKLEPRIKKLCATEL
                     KDQKSLLLLGRGYQFAAALEGALKIKEISYMHSEGVLAGELKHGVLALVDENLPIIAF
                     GTRDSLFPKVVSSIEQVTARKGHPIIICNENDEVWAQKSKSIDLQTLEVPQTVDCLQG
                     LINIIPLQLMSYWLAVNKGIDVDFPRNLAKSVTVE"
     gene            complement(<246138..>247682)
                     /gene="APE1"
                     /locus_tag="YKL103C"
                     /gene_synonym="API; LAP4; YSC1"
                     /db_xref="GeneID:853758"
     mRNA            complement(<246138..>247682)
                     /gene="APE1"
                     /locus_tag="YKL103C"
                     /gene_synonym="API; LAP4; YSC1"
                     /product="Ape1p"
                     /transcript_id="NM_001179669.1"
                     /db_xref="GI:296146275"
                     /db_xref="GeneID:853758"
     CDS             complement(246138..247682)
                     /gene="APE1"
                     /locus_tag="YKL103C"
                     /gene_synonym="API; LAP4; YSC1"
                     /EC_number="3.4.11.22"
                     /note="Vacuolar aminopeptidase yscI; zinc
                     metalloproteinase that belongs to the peptidase family
                     M18; often used as a marker protein in studies of
                     autophagy and cytosol to vacuole targeting (CVT) pathway;
                     protein increases in abundance and relative distribution
                     to cytoplasmic foci increases upon DNA replication stress"
                     /codon_start=1
                     /product="Ape1p"
                     /protein_id="NP_012819.1"
                     /db_xref="GI:6322746"
                     /db_xref="SGD:S000001586"
                     /db_xref="GeneID:853758"
                     /translation="MEEQREILEQLKKTLQMLTVEPSKNNQIANEEKEKKENENSWCI
                     LEHNYEDIAQEFIDFIYKNPTTYHVVSFFAELLDKHNFKYLSEKSNWQDSIGEDGGKF
                     YTIRNGTNLSAFILGKNWRAEKGVGVIGSHVDALTVKLKPVSFKDTAEGYGRIAVAPY
                     GGTLNELWLDRDLGIGGRLLYKKKGTNEIKSALVDSTPLPVCRIPSLAPHFGKPAEGP
                     FDKEDQTIPVIGFPTPDEEGNEPPTDDEKKSPLFGKHCIHLLRYVAKLAGVEVSELIQ
                     MDLDLFDVQKGTIGGIGKHFLFAPRLDDRLCSFAAMIALICYAKDVNTEESDLFSTVT
                     LYDNEEIGSLTRQGAKGGLLESVVERSSSAFTKKPVDLHTVWANSIILSADVNHLYNP
                     NFPEVYLKNHFPVPNVGITLSLDPNGHMATDVVGTALVEELARRNGDKVQYFQIKNNS
                     RSGGTIGPSLASQTGARTIDLGIAQLSMHSIRAATGSKDVGLGVKFFNGFFKHWRSVY
                     DEFGEL"
     gene            <248920..>253476
                     /gene="HSL1"
                     /locus_tag="YKL101W"
                     /gene_synonym="ELM2; NIK1"
                     /db_xref="GeneID:853760"
     mRNA            <248920..>253476
                     /gene="HSL1"
                     /locus_tag="YKL101W"
                     /gene_synonym="ELM2; NIK1"
                     /product="protein kinase HSL1"
                     /transcript_id="NM_001179667.2"
                     /db_xref="GI:330443651"
                     /db_xref="GeneID:853760"
     CDS             248920..253476
                     /gene="HSL1"
                     /locus_tag="YKL101W"
                     /gene_synonym="ELM2; NIK1"
                     /EC_number="2.7.11.1"
                     /note="Nim1p-related protein kinase; regulates the
                     morphogenesis and septin checkpoints; associates with the
                     assembled septin filament; required along with Hsl7p for
                     bud neck recruitment, phosphorylation, and degradation of
                     Swe1p"
                     /codon_start=1
                     /product="protein kinase HSL1"
                     /protein_id="NP_012821.2"
                     /db_xref="GI:330443652"
                     /db_xref="SGD:S000001584"
                     /db_xref="GeneID:853760"
                     /translation="MTGHVSKTSHVPKGRPSSLAKKAAKRAMAKVNSNPKRASGHLER
                     VVQSVNDATKRLSQPDSTVSVATKSSKRKSRDTVGPWKLGKTLGKGSSGRVRLAKNME
                     TGQLAAIKIVPKKKAFVHCSNNGTVPNSYSSSMVTSNVSSPSIASREHSNHSQTNPYG
                     IEREIVIMKLISHTNVMALFEVWENKSELYLVLEYVDGGELFDYLVSKGKLPEREAIH
                     YFKQIVEGVSYCHSFNICHRDLKPENLLLDKKNRRIKIADFGMAALELPNKLLKTSCG
                     SPHYASPEIVMGRPYHGGPSDVWSCGIVLFALLTGHLPFNDDNIKKLLLKVQSGKYQM
                     PSNLSSEARDLISKILVIDPEKRITTQEILKHPLIKKYDDLPVNKVLRKMRKDNMARG
                     KSNSDLHLLNNVSPSIVTLHSKGEIDESILRSLQILWHGVSRELITAKLLQKPMSEEK
                     LFYSLLLQYKQRHSISLSSSSENKKSATESSVNEPRIEYASKTANNTGLRSENNDVKT
                     LHSLEIHSEDTSTVNQNNAITGVNTEINAPVLAQKSQFSINTLSQPESDKAEAEAVTL
                     PPAIPIFNASSSRIFRNSYTSISSRSRRSLRLSNSRLSLSASTSRETVHDNEMPLPQL
                     PKSPSRYSLSRRAIHASPSTKSIHKSLSRKNIAATVAARRTLQNSASKRSLYSLQSIS
                     KRSLNLNDLLVFDDPLPSKKPASENVNKSEPHSLESDSDFEILCDQILFGNALDRILE
                     EEEDNEKERDTQRQRQNDTKSSADTFTISGVSTNKENEGPEYPTKIEKNQFNMSYKPS
                     ENMSGLSSFPIFEKENTLSSSYLEEQKPKRAALSDITNSFNKMNKQEGMRIEKKIQRE
                     QLQKKNDRPSPLKPIQHQELRVNSLPNDQGKPSLSLDPRRNISQPVNSKVESLLQGLK
                     FKKEPASHWTHERGSLFMSEHVEDEKPVKASDVSIESSYVPLTTVATSSRDPSVLAES
                     STIQKPMLSLPSSFLNTSMTFKNLSQILADDGDDKHLSVPQNQSRSVAMSHPLRKQSA
                     KISLTPRSNLNANLSVKRNQGSPGSYLSNDLDGISDMTFAMEIPTNTFTAQAIQLMNN
                     DTDNNKINTSPKASSFTKEKVIKSAAYISKEKEPDNSDTNYIPDYTIPNTYDEKAINI
                     FEDAPSDEGSLNTSSSESDSRASVHRKAVSIDTMATTNVLTPATNVRVSLYWNNNSSG
                     IPRETTEEILSKLRLSPENPSNTHMQKRFSSTRGSRDSNALGISQSLQSMFKDLEEDQ
                     DGHTSQADILESSMSYSKRRPSEESVNPKQRVTMLFDEEEEESKKVGGGKIKEEHTKL
                     DNKISEESSQLVLPVVEKKENANNTENNYSKIPKPSTIKVTKDTAMESNTQTHTKKPI
                     LKSVQNVEVEEAPSSDKKNWFVKLFQNFSSHNNATKASKNHVTNISFDDAHMLTLNEF
                     NKNSIDYQLKNLDHKFGRKVVEYDCKFVKGNFKFKIKITSTPNASTVITVKKRSKHSN
                     TSSNKAFEKFNDDVERVIRNAGRS"
     gene            complement(<253697..>255460)
                     /locus_tag="YKL100C"
                     /db_xref="GeneID:853761"
     mRNA            complement(<253697..>255460)
                     /locus_tag="YKL100C"
                     /product="hypothetical protein"
                     /transcript_id="NM_001179666.1"
                     /db_xref="GI:296146277"
                     /db_xref="GeneID:853761"
     CDS             complement(253697..255460)
                     /locus_tag="YKL100C"
                     /EC_number="3.4.23.-"
                     /note="hypothetical protein; has similarity to a human
                     minor histocompatibility antigen and signal peptide
                     peptidases; YKL100C is not an essential gene"
                     /codon_start=1
                     /product="hypothetical protein"
                     /protein_id="NP_012822.1"
                     /db_xref="GI:6322749"
                     /db_xref="SGD:S000001583"
                     /db_xref="GeneID:853761"
                     /translation="MDKYLNSFVDHLSEWSSRAFRNNSSSANQSASNKELEQVFEQIN
                     AIVENHNNKLTTAFDKISYRVAHKITHLVESHSLVFNYATLVLIASALVVIGSFTSIS
                     SIPFTALPPTREHSLFDPTDFDVDHDCHVIYRENDEDKKKKKKSKRFFDMMDEKHAII
                     LPLTSGCTLLALYFVIKKLHLNWLKYVVKILNFNITLLNIPAGTFVYSYFLNSLFRNL
                     SHLASWNPLVVLPRYRVTIADDNEDLNKIGGFVTNLNYKDGLTNSVVHKKTLDEIEKD
                     HWMKHFYRRELVEPKDIKSKRQISNMYLNSALIVSFVLSIVSTVYFYLSPNDWLISNA
                     VSMNMAIWSIAQLKLKNLKSGALILIALFFYDICFVFGTDVMVTVATNLDIPVKLSLP
                     VKFNTAQNNFNFSILGLGDIALPGMFIAMCYKYDIWKWHLDHDDTEFHFLNWSYVGKY
                     FITAMVSYVASLVSAMVSLSIFNTAQPALLYIVPSLLISTILVACWNKDFKQFWNFQY
                     DTIEVDKSLKKAIEKKENSITYSTFILSEYYNDADKYALLGDDVNENFDDDEEFVQEE
                     DLSDSSEEELSEEDLLDDESS"
     gene            complement(<255720..>256472)
                     /gene="UTP11"
                     /locus_tag="YKL099C"
                     /db_xref="GeneID:853762"
     mRNA            complement(<255720..>256472)
                     /gene="UTP11"
                     /locus_tag="YKL099C"
                     /product="Utp11p"
                     /transcript_id="NM_001179665.1"
                     /db_xref="GI:296146278"
                     /db_xref="GeneID:853762"
     CDS             complement(255720..256472)
                     /gene="UTP11"
                     /locus_tag="YKL099C"
                     /note="Subunit of U3-containing Small Subunit (SSU)
                     processome complex; involved in production of 18S rRNA and
                     assembly of small ribosomal subunit"
                     /codon_start=1
                     /product="Utp11p"
                     /protein_id="NP_012823.2"
                     /db_xref="GI:83722564"
                     /db_xref="SGD:S000001582"
                     /db_xref="GeneID:853762"
                     /translation="MAKLVHDVQKKQHRERSQLTSRSRYGFLEKHKDYVKRAQDFHRK
                     QSTLKVLREKAKERNPDEYYHAMHSRKTDAKGLLISSRHGDEEDESLSMDQVKLLKTQ
                     DSNYVRTLRQIELKKLEKGAKQLMFKSSGNHTIFVDSREKMNEFTPEKFFNTTSEMVN
                     RSENRLTKDQLAQDISNNRNASSIMPKESLDKKKLKKFKQVKQHLQRETQLKQVQQRM
                     DAQRELLKKGSKKKIVDSSGKISFKWKKQRKR"
     gene            <256770..>257843
                     /gene="MTC2"
                     /locus_tag="YKL098W"
                     /db_xref="GeneID:853763"
     mRNA            <256770..>257843
                     /gene="MTC2"
                     /locus_tag="YKL098W"
                     /product="Mtc2p"
                     /transcript_id="NM_001179664.1"
                     /db_xref="GI:296146279"
                     /db_xref="GeneID:853763"
     CDS             256770..257843
                     /gene="MTC2"
                     /locus_tag="YKL098W"
                     /note="hypothetical protein; mtc2 is synthetically sick
                     with cdc13-1"
                     /codon_start=1
                     /product="Mtc2p"
                     /protein_id="NP_012824.1"
                     /db_xref="GI:6322751"
                     /db_xref="SGD:S000001581"
                     /db_xref="GeneID:853763"
                     /translation="MGDHNLPDFQTCLKFSVTAKKSFLCMYRDSVSKEKLASSMPSTC
                     DIQLKRAINDAYPGGGIKVTVLNSTTASLDSLATTHVKEFEIVIIPDINSLLQPDQAK
                     LVKIMRDCTVAIEKAQSTRIFIGVVHWNNPVQPSGAAKDGDEAGKPAPKTRIFLPTSF
                     RMGAWLKHKFWFACAPPYLDFESSTESSINTRANNSIGMAEEEKQEPESKRSIILNEE
                     ANLNDVFVGSTVRRYILDIMVHLRTHRLTYNAKAGGVYTNSLDDVVLLSRLIGLHSGK
                     MFVSPSHVKEASRWYFPMHLELVQRSSMDSSLLYGSDPNLVDEMLEKLAKIKCEEVNE
                     FENPLFLESLVVKNVLSKVVPPV"
     gene            complement(<259073..>259222)
                     /locus_tag="YKL096C-B"
                     /db_xref="GeneID:1500486"
     mRNA            complement(<259073..>259222)
                     /locus_tag="YKL096C-B"
                     /product="hypothetical protein"
                     /transcript_id="NM_001184604.1"
                     /db_xref="GI:296146280"
                     /db_xref="GeneID:1500486"
     CDS             complement(259073..259222)
                     /locus_tag="YKL096C-B"
                     /note="hypothetical protein; identified by gene-trapping,
                     microarray-based expression analysis, and genome-wide
                     homology searching"
                     /codon_start=1
                     /product="hypothetical protein"
                     /protein_id="NP_878110.1"
                     /db_xref="GI:33578047"
                     /db_xref="SGD:S000028667"
                     /db_xref="GeneID:1500486"
                     /translation="MKLFILDYEKKRTKIGKGMARRELKMMNKKPDLYTIIVSYFSIF
                     SLFFF"
     gene            <259253..>259531
                     /gene="CWP2"
                     /locus_tag="YKL096W-A"
                     /gene_synonym="LPR1; YKL097W-A"
                     /db_xref="GeneID:853765"
     mRNA            <259253..>259531
                     /gene="CWP2"
                     /locus_tag="YKL096W-A"
                     /gene_synonym="LPR1; YKL097W-A"
                     /product="Cwp2p"
                     /transcript_id="NM_001180025.1"
                     /db_xref="GI:296146281"
                     /db_xref="GeneID:853765"
     CDS             259253..259531
                     /gene="CWP2"
                     /locus_tag="YKL096W-A"
                     /gene_synonym="LPR1; YKL097W-A"
                     /note="Covalently linked cell wall mannoprotein; major
                     constituent of the cell wall; plays a role in stabilizing
                     the cell wall; involved in low pH resistance; precursor is
                     GPI-anchored"
                     /codon_start=1
                     /product="Cwp2p"
                     /protein_id="NP_012826.1"
                     /db_xref="GI:6322753"
                     /db_xref="SGD:S000001956"
                     /db_xref="GeneID:853765"
                     /translation="MQFSTVASVAFVALANFVAAESAAAISQITDGQIQATTTATTEA
                     TTTAAPSSTVETVSPSSTETISQQTENGAAKAAVGMGAGALAAAAMLL"
     gene            <261132..>261851
                     /gene="CWP1"
                     /locus_tag="YKL096W"
                     /gene_synonym="YJU1"
                     /db_xref="GeneID:853766"
     mRNA            <261132..>261851
                     /gene="CWP1"
                     /locus_tag="YKL096W"
                     /gene_synonym="YJU1"
                     /product="Cwp1p"
                     /transcript_id="NM_001179662.1"
                     /db_xref="GI:296146282"
                     /db_xref="GeneID:853766"
     CDS             261132..261851
                     /gene="CWP1"
                     /locus_tag="YKL096W"
                     /gene_synonym="YJU1"
                     /note="Cell wall mannoprotein that localizes to birth
                     scars of daughter cells; linked to a beta-1,3- and
                     beta-1,6-glucan heteropolymer through a phosphodiester
                     bond; required for propionic acid resistance"
                     /codon_start=1
                     /product="Cwp1p"
                     /protein_id="NP_012827.1"
                     /db_xref="GI:6322754"
                     /db_xref="SGD:S000001579"
                     /db_xref="GeneID:853766"
                     /translation="MKFSTALSVALFALAKMVIADSEEFGLVSIRSGSDLQYLSVYSD
                     NGTLKLGSGSGSFEATITDDGKLKFDDDKYAVVNEDGSFKEGSESDAATGFSIKDGHL
                     NYKSSSGFYAIKDGSSYIFSSKQSDDATGVAIRPTSKSGSVAADFSPSDSSSSSSASA
                     SSASASSSTKHSSSIESVETSTTVETSSASSPTASVISQITDGQIQAPNTVYEQTENA
                     GAKAAVGMGAGALAVAAAYLL"
     gene            <262277..>263113
                     /gene="YJU2"
                     /locus_tag="YKL095W"
                     /gene_synonym="CWC16"
                     /db_xref="GeneID:853767"
     mRNA            <262277..>263113
                     /gene="YJU2"
                     /locus_tag="YKL095W"
                     /gene_synonym="CWC16"
                     /product="Yju2p"
                     /transcript_id="NM_001179661.1"
                     /db_xref="GI:296146283"
                     /db_xref="GeneID:853767"
     CDS             262277..263113
                     /gene="YJU2"
                     /locus_tag="YKL095W"
                     /gene_synonym="CWC16"
                     /note="Essential protein required for pre-mRNA splicing;
                     associates transiently with the spliceosomal NTC
                     ('nineteen complex') and acts after Prp2p to promote the
                     first catalytic reaction of splicing"
                     /codon_start=1
                     /product="Yju2p"
                     /protein_id="NP_012828.1"
                     /db_xref="GI:6322755"
                     /db_xref="SGD:S000001578"
                     /db_xref="GeneID:853767"
                     /translation="MSERKAINKYYPPDYNPLEAEKLSRKMAKKLKTMNKSHASIRLM
                     TPFSMRCLECNEYIPKSRKFNGKKELLKEKYLDSIKIYRLTISCPRCANSIAFRTDPG
                     NSDYVMEVGGVRNYVPQKPNDDLNAKTAVESIDETLQRLVREKEMEQNEKMGIKEQAD
                     DKMDLLEKRLAKIQQEQEDDEELENLRKKNLEMSQRAEMINRSKHAQQEKAVTTDDLD
                     NLVDQVFDNHRQRTNKPGNNNDEKRTPLFNPTSTKGKIQKKSSVRTNPLGIVIKRGKS
                     LK"
     gene            <263349..>264290
                     /gene="YJU3"
                     /locus_tag="YKL094W"
                     /db_xref="GeneID:853768"
     mRNA            <263349..>264290
                     /gene="YJU3"
                     /locus_tag="YKL094W"
                     /product="Yju3p"
                     /transcript_id="NM_001179660.1"
                     /db_xref="GI:296146284"
                     /db_xref="GeneID:853768"
     CDS             263349..264290
                     /gene="YJU3"
                     /locus_tag="YKL094W"
                     /EC_number="3.1.1.23"
                     /note="Monoglyceride lipase (MGL); functional ortholog of
                     mammalian MGL, localizes to lipid particles and membranes,
                     also member of the eukaryotic serine hydrolase family"
                     /codon_start=1
                     /product="Yju3p"
                     /protein_id="NP_012829.1"
                     /db_xref="GI:6322756"
                     /db_xref="SGD:S000001577"
                     /db_xref="GeneID:853768"
                     /translation="MAPYPYKVQTTVPELQYENFDGAKFGYMFWPVQNGTNEVRGRVL
                     LIHGFGEYTKIQFRLMDHLSLNGYESFTFDQRGAGVTSPGRSKGVTDEYHVFNDLEHF
                     VEKNLSECKAKGIPLFMWGHSMGGGICLNYACQGKHKNEISGYIGSGPLIILHPHTMY
                     NKPTQIIAPLLAKFLPRVRIDTGLDLKGITSDKAYRAFLGSDPMSVPLYGSFRQIHDF
                     MQRGAKLYKNENNYIQKNFAKDKPVIIMHGQDDTINDPKGSEKFIQDCPSADKELKLY
                     PGARHSIFSLETDKVFNTVFNDMKQWLDKHTTTEAKP"
     gene            <264789..>265808
                     /gene="MBR1"
                     /locus_tag="YKL093W"
                     /db_xref="GeneID:853769"
     mRNA            <264789..>265808
                     /gene="MBR1"
                     /locus_tag="YKL093W"
                     /product="Mbr1p"
                     /transcript_id="NM_001179659.1"
                     /db_xref="GI:296146285"
                     /db_xref="GeneID:853769"
     CDS             264789..265808
                     /gene="MBR1"
                     /locus_tag="YKL093W"
                     /note="Protein involved in mitochondrial functions and
                     stress response; overexpression suppresses growth defects
                     of hap2, hap3, and hap4 mutants; MBR1 has a paralog, ISF1,
                     that arose from the whole genome duplication"
                     /codon_start=1
                     /product="Mbr1p"
                     /protein_id="NP_012830.1"
                     /db_xref="GI:6322757"
                     /db_xref="SGD:S000001576"
                     /db_xref="GeneID:853769"
                     /translation="MRMEKTTDKPLSAGDMNDEYSRGPIDDIDCLNFFERAVQDPCCE
                     ACDTEDADEELRAKLSSFNFQPDSSPCNAKCQQTLNPLCKIDEALPAESELAPSRNGS
                     VSEANSDTNSIASTVHDPVDSKYGGMPSLRKAKTTSYFTSSSSNNTTMRNPLKKCNTN
                     INGLLVNGRSSSSSRQSIPELFSGACTKKKNNVLLKSETPNSEFSSNSLQHCNSRSFS
                     LPRSRSRSSAIAIPTHLYGLEKYVSPGLDTLTADPEESIERFSNNRPREISSCCPNDT
                     GDTSSSLSHSNTSSSLNFPLGTNTNQFHQPRQPVQQQQSSKPNFGAGRKKSFIEMSLA
                     SSFAG"
     gene            complement(<266145..>269459)
                     /gene="BUD2"
                     /locus_tag="YKL092C"
                     /gene_synonym="CLA2; ERC25"
                     /db_xref="GeneID:853770"
     mRNA            complement(<266145..>269459)
                     /gene="BUD2"
                     /locus_tag="YKL092C"
                     /gene_synonym="CLA2; ERC25"
                     /product="Bud2p"
                     /transcript_id="NM_001179658.1"
                     /db_xref="GI:296146286"
                     /db_xref="GeneID:853770"
     CDS             complement(266145..269459)
                     /gene="BUD2"
                     /locus_tag="YKL092C"
                     /gene_synonym="CLA2; ERC25"
                     /note="GTPase activating factor for Rsr1p/Bud1p; plays a
                     role in spindle position checkpoint distinct from its role
                     in bud site selection; required for both axial and bipolar
                     budding patterns; mutants exhibit random budding in all
                     cell types"
                     /codon_start=1
                     /product="Bud2p"
                     /protein_id="NP_012831.1"
                     /db_xref="GI:6322758"
                     /db_xref="SGD:S000001575"
                     /db_xref="GeneID:853770"
                     /translation="MSSNNEPAQSRTSYFKLNEFLSNVKHYKNTFKGEIQWCNNLSLN
                     DWKTHYLQITSTGALTHSIDELTADSTNIQPIIKHLQQCRIEIIKDKHSSFKDINANC
                     NFIIQVNTSGKDNKVYLRVKSWSDFKKLLTCLIWWSSMKTNGIFNKFQVSRPLEFKSK
                     KMAKPESLLVYKLNVFGPIVKNIVLPPATNILESPDIINNDDNSVGWFSAMGVLKSNG
                     MLDLLLQSDGSLIYSLNISQLLRSEIRILDSSVLQSENSLFLGELPLLRSQLGLEKFR
                     IENIASAATNSSDISQEIIVEFPLRIDLEDCFIALQSFARSEYLSITGSDKSNDMKIS
                     NSFKISILEANFQSINLNDKNNTPWSIFTDITAWGHTWARTSMVSNSSNPFWREEFQF
                     NELLRLTNSYLEIKQLFHDLNNKKRLRLIGKIKITQEIINDTRYNKETRLPIMDVDNK
                     NFQIGTICIKISSNLNFILPSTNFVKLEKLLMNANLSMVSNLIYKSSSSMENDNKLTQ
                     TSIIFLDIFQSLSRIEEWFHVLIDKELAKIDGTVSRINQKNLDSKHVFNSLFRGNSIL
                     TKSIEQYFFRVGNEYLSKALSAILKEIIESNKSCELDPARVKEKDEVKKRKIIADNYK
                     RLYSWVTKIWKRLYATSNDLPIEIRNVLKIFRQKLEIICIDDTLQIILNGISGLLFLR
                     FFCPVILNPKLFKYVSQNLNETARRNLTLISKVLLNLSTLTQFANKEPWLMKMNNFID
                     KRHNDLLDYIDKMTQKKLDFNSKILNLSSTISRPKLAIEQTMLDDLPQIPYLLDKNLR
                     ETEFVNLIVNFSQEDMTKMEKYNHMDNGGKGELIEEEGLLSGSSLNLSVDKKDLDSPI
                     EVKPEIGELEFEKITENNTEIFGDDLMNLLKSDDVGSRSRDLDNGANSGIKFNSIIPK
                     AEEEKHAMKELEQESCLLYNRINHIRKRLSGYECASSTLFEDKKYSISLSHKIFYEEI
                     KEGKEIVLKLLNKPTNENSSARLQKFFTKGVSSKSNNTVGDSYCKFLTIDVSDENPKS
                     SNKTSVHGTSSENGAKDDYLTLPNSQGKGNLGNRFSPTKLSRIMRKPPNADVPKEQNS
                     RKLTRWFKKKKETGGS"
     gene            complement(<269718..>270650)
                     /locus_tag="YKL091C"
                     /gene_synonym="SFH1"
                     /db_xref="GeneID:853771"
     mRNA            complement(<269718..>270650)
                     /locus_tag="YKL091C"
                     /gene_synonym="SFH1"
                     /product="phosphatidylinositol/phosphatidylcholine-binding
                     protein"
                     /transcript_id="NM_001179657.1"
                     /db_xref="GI:296146287"
                     /db_xref="GeneID:853771"
     CDS             complement(269718..270650)
                     /locus_tag="YKL091C"
                     /gene_synonym="SFH1"
                     /note="Putative phosphatidylinositol/phosphatidylcholine
                     transfer protein; possibly involved in lipid metabolism;
                     localizes to the nucleus; contains a CRAL/TRIO domain and
                     binds several lipids in a large-scale study; YKL091C has a
                     paralog, SEC14, that arose from the whole genome
                     duplication"
                     /codon_start=1
                     /product="phosphatidylinositol/phosphatidylcholine-binding
                     protein"
                     /protein_id="NP_012832.1"
                     /db_xref="GI:6322759"
                     /db_xref="SGD:S000001574"
                     /db_xref="GeneID:853771"
                     /translation="MTTSILDTYPQICSPNALPGTPGNLTKEQEEALLQFRSILLEKN
                     YKERLDDSTLLRFLRARKFDINASVEMFVETERWREEYGANTIIEDYENNKEAEDKER
                     IKLAKMYPQYYHHVDKDGRPLYFEELGGINLKKMYKITTEKQMLRNLVKEYELFATYR
                     VPACSRRAGYLIETSCTVLDLKGISLSNAYHVLSYIKDVADISQNYYPERMGKFYIIH
                     SPFGFSTMFKMVKPFLDPVTVSKIFILGSSYKKELLKQIPIENLPVKYGGTSVLHNPN
                     DKFYYSDIGPWRDPRYIGPEGEIPNIFGKFTVTS"
     gene            <271878..>273209
                     /gene="CUE2"
                     /locus_tag="YKL090W"
                     /db_xref="GeneID:853772"
     mRNA            <271878..>273209
                     /gene="CUE2"
                     /locus_tag="YKL090W"
                     /product="Cue2p"
                     /transcript_id="NM_001179656.1"
                     /db_xref="GI:296146288"
                     /db_xref="GeneID:853772"
     CDS             271878..273209
                     /gene="CUE2"
                     /locus_tag="YKL090W"
                     /note="hypothetical protein; has two CUE domains that bind
                     ubiquitin, which may facilitate intramolecular
                     monoubiquitination"
                     /codon_start=1
                     /product="Cue2p"
                     /protein_id="NP_012833.1"
                     /db_xref="GI:6322760"
                     /db_xref="SGD:S000001573"
                     /db_xref="GeneID:853772"
                     /translation="MSMDNNDDHESKLSILMDMFPAISKSKLQVHLLENNNDLDLTIG
                     LLLKENDDKSTVDNELHQLYDMFPQLDCSVIKDQFVINEKSVESTISDLLNYETLQKL
                     KDNQANSPDSVKRNEKKNNWESTNDHIESIIKFTDAPKNIAQEYLAENGFDTVKAIIK
                     IILDYYDKRDFKKDVDTFKVKRSPNTTVRGGRVQSSTGLAHVLKKGKESANVAQESLK
                     RPRSYKHSLDSPQMVELNELVADNRDLKAINHEFLQKCLQFYDGDVVKVLNISSLLIE
                     DDKNITKTWNFDEGFTLTSRDNCKQHLPKFSTPQISRRNEVGNTYKLPLHDKETPEGA
                     VPVINNLFQTYRLDFHGFLPSEAVSTLKLALNKWWSKEVAERELNSHNINSYGSKVQF
                     VSPLIVVTGRGIHSIGGISKVRLQVKSFLEKNHYIFWEESSYFRIEGKKKK"
     gene            <273394..>275043
                     /gene="MIF2"
                     /locus_tag="YKL089W"
                     /db_xref="GeneID:853773"
     mRNA            <273394..>275043
                     /gene="MIF2"
                     /locus_tag="YKL089W"
                     /product="Mif2p"
                     /transcript_id="NM_001179655.1"
                     /db_xref="GI:296146289"
                     /db_xref="GeneID:853773"
     CDS             273394..275043
                     /gene="MIF2"
                     /locus_tag="YKL089W"
                     /note="Protein required for structural integrity of
                     elongating spindles; localizes to the kinetochore;
                     interacts with histones H2A, H2B, and H4; phosphorylated
                     by Ipl1p; orthologous to human centromere
                     constitutive-associated network (CCAN) subunit CENP-C and
                     fission yeast cnp3"
                     /codon_start=1
                     /product="Mif2p"
                     /protein_id="NP_012834.1"
                     /db_xref="GI:6322761"
                     /db_xref="SGD:S000001572"
                     /db_xref="GeneID:853773"
                     /translation="MDYMKLGLKSRKTGIDVKQDIPKDEYSMENIDDFFKDDETSLIS
                     MRRKSRRKSSLFLPSTLNGDTKNVLPPFLQSYKSQDDEVVQSPSGKGDGSRRSSLLSH
                     QSNFLSPANDFEPIEEEPEQEENDIRGNDFATPITQKLSKPTYKRKYSTRYSLDTSES
                     PSVRLTPDRITNKNVYSDVPDLVADEDDDDRVNTSLNTSDNALLEDELEDDGFIPESE
                     EDGDYIESDSSLDSGSDSASDSDGDNTYQEVEEEAEVNTNDNEDDYIRRQASDVVRTD
                     SIIDRNGLRKSTRVKVAPLQYWRNEKIVYKRKSNKPVLDIDKIVTYDESEDEEEILAA
                     QRRKKQKKKPTPTRPYNYVPTGRPRGRPKKDPNAKENLIPEDPNEDIIERIESGGIEN
                     GEWLKHGILEANVKISDTKEETKDEIIAFAPNLSQTEQVKDTKDENFALEIMFDKHKE
                     YFASGILKLPAISGQKKLSNSFRTYITFHVIQGIVEVTVCKNKFLSVKGSTFQIPAFN
                     EYAIANRGNDEAKMFFVQVTVSEDANDDNDKELDSTFDTFG"
     gene            <275283..>276998
                     /gene="CAB3"
                     /locus_tag="YKL088W"
                     /db_xref="GeneID:853774"
     mRNA            <275283..>276998
                     /gene="CAB3"
                     /locus_tag="YKL088W"
                     /product="phosphopantothenoylcysteine decarboxylase
                     complex subunit CAB3"
                     /transcript_id="NM_001179654.1"
                     /db_xref="GI:296146290"
                     /db_xref="GeneID:853774"
     CDS             275283..276998
                     /gene="CAB3"
                     /locus_tag="YKL088W"
                     /note="Subunit of PPCDC and CoA-SPC complexes involved in
                     CoA biosynthesis; subunits of the
                     phosphopantothenoylcysteine decarboxylase (PPCDC) complex
                     are: Cab3p, Sis2p, Vhs3p, while the subunits of the
                     CoA-synthesizing protein complex (CoA-SPC) are: Cab2p,
                     Cab3p, Cab4p, and Cab5p as well as Sis2p and Vhs3p; null
                     mutant lethality is complemented by E. coli coaBC"
                     /codon_start=1
                     /product="phosphopantothenoylcysteine decarboxylase
                     complex subunit CAB3"
                     /protein_id="NP_012835.1"
                     /db_xref="GI:6322762"
                     /db_xref="SGD:S000001571"
                     /db_xref="GeneID:853774"
                     /translation="MTDEKVNSDQNMNGKQGVNLISSLPTTQVPVSILTNKERRKSIH
                     DESNFERSDSHEDQSKSNSNRRNIYKNDYSTNLRDFSFANLKQNSERNKDGHEIQINT
                     SMPANTNGQQKRFSPSLPSAVSFTVPEVERLPYHRYSISNKPGKQQQQQEQLQQNQQQ
                     EEQQKAQLQEQNQRAKQQEEVKQIQEQVQKKQTERQQLIDEKERIANAIFKENTTNDG
                     TDIRKHSVSSGTSNSEDEVDSPSMEKNSIVHMPGDFIYFNPKSNASKPITAKAAPLSA
                     NNSTHKNKEVITAPTGPRVPFTEFFQKEDDKKFHILIGATGSVATIKVPLIIDKLFKI
                     YGPEKISIQLIVTKPAEHFLKGLKMSTHVKIWREEDAWVFDAVNKNDTSLSLNLILHH
                     ELRKWADIFLIAPLSANTLAKLANGICNNLLTSVMRDWSPLTPVLIAPAMNTFMYINP
                     MTKKHLTSLVQDYPFIQVLKPVEKVLICGDIGMGGMREWTDIVEIVRRRINEIRKARD
                     EETGDKEQEQEEQEGADNEDDDDEDDEEDEEDEEEEEALNETASDESNDEEDEEDEED
                     VKTEV"
     gene            complement(<277189..>277863)
                     /gene="CYT2"
                     /locus_tag="YKL087C"
                     /db_xref="GeneID:853775"
     mRNA            complement(<277189..>277863)
                     /gene="CYT2"
                     /locus_tag="YKL087C"
                     /product="cytochrome c1 heme lyase CYT2"
                     /transcript_id="NM_001179653.1"
                     /db_xref="GI:296146291"
                     /db_xref="GeneID:853775"
     CDS             complement(277189..277863)
                     /gene="CYT2"
                     /locus_tag="YKL087C"
                     /EC_number="4.4.1.-"
                     /note="Cytochrome c1 heme lyase; involved in maturation of
                     cytochrome c1, which is a subunit of the mitochondrial
                     ubiquinol-cytochrome-c reductase; links heme covalently to
                     apocytochrome c1"
                     /codon_start=1
                     /product="cytochrome c1 heme lyase CYT2"
                     /protein_id="NP_012836.1"
                     /db_xref="GI:6322763"
                     /db_xref="SGD:S000001570"
                     /db_xref="GeneID:853775"
                     /translation="MMSSDQQGKCPVDEETKKLWLREHGNEAHPGATAPGNQLECSAN
                     PQDNDKTPEYHTTVDLSQSREVSTIPRTNSDRNWIYPSEKQFYEAMMKKNWDPNSDDM
                     KVVVPLHNSINERVWNYIKSWEDKQGGEACGGIKLTNFKGDSKKLTPRAWFRSRILHL
                     AKPFDRHDWQIDRCGKTVDYVIDFYSTDLNDANSQQQPLIYLDVRPKLNSFEGFRLRF
                     WKSLGF"
     gene            <278281..>278664
                     /gene="SRX1"
                     /locus_tag="YKL086W"
                     /db_xref="GeneID:853776"
     mRNA            <278281..>278664
                     /gene="SRX1"
                     /locus_tag="YKL086W"
                     /product="Srx1p"
                     /transcript_id="NM_001179652.1"
                     /db_xref="GI:296146292"
                     /db_xref="GeneID:853776"
     CDS             278281..278664
                     /gene="SRX1"
                     /locus_tag="YKL086W"
                     /EC_number="1.8.98.2"
                     /note="Sulfiredoxin; contributes to oxidative stress
                     resistance by reducing cysteine-sulfinic acid groups in
                     the peroxiredoxin Tsa1p, which is formed upon exposure to
                     oxidants; conserved in higher eukaryotes; protein
                     abundance increases in response to DNA replication stress"
                     /codon_start=1
                     /product="Srx1p"
                     /protein_id="NP_012837.1"
                     /db_xref="GI:6322764"
                     /db_xref="SGD:S000001569"
                     /db_xref="GeneID:853776"
                     /translation="MSLQSNSVKPTEIPLSEIRRPLAPVLDPQKIDAMVATMKGIPTA
                     SKTCSLEQAEAAASAGELPPVDVLGVRVKGQTLYYAFGGCHRLQAYDRRARETQNAAF
                     PVRCRVLPATPRQIRMYLGSSLDIE"
     gene            <279123..>280127
                     /gene="MDH1"
                     /locus_tag="YKL085W"
                     /db_xref="GeneID:853777"
     mRNA            <279123..>280127
                     /gene="MDH1"
                     /locus_tag="YKL085W"
                     /product="malate dehydrogenase MDH1"
                     /transcript_id="NM_001179651.1"
                     /db_xref="GI:296146293"
                     /db_xref="GeneID:853777"
     CDS             279123..280127
                     /gene="MDH1"
                     /locus_tag="YKL085W"
                     /EC_number="1.1.1.37"
                     /note="Mitochondrial malate dehydrogenase; catalyzes
                     interconversion of malate and oxaloacetate; involved in
                     the tricarboxylic acid (TCA) cycle; phosphorylated"
                     /codon_start=1
                     /product="malate dehydrogenase MDH1"
                     /protein_id="NP_012838.1"
                     /db_xref="GI:6322765"
                     /db_xref="SGD:S000001568"
                     /db_xref="GeneID:853777"
                     /translation="MLSRVAKRAFSSTVANPYKVTVLGAGGGIGQPLSLLLKLNHKVT
                     DLRLYDLKGAKGVATDLSHIPTNSVVKGFTPEEPDGLNNALKDTDMVLIPAGVPRKPG
                     MTRDDLFAINASIVRDLAAATAESAPNAAILVISNPVNSTVPIVAQVLKNKGVYNPKK
                     LFGVTTLDSIRAARFISEVENTDPTQERVNVIGGHSGITIIPLISQTNHKLMSDDKRH
                     ELIHRIQFGGDEVVKAKNGAGSATLSMAHAGAKFANAVLSGFKGERDVIEPSFVDSPL
                     FKSEGIEFFASPVTLGPDGIEKIHPIGELSSEEEEMLQKCKETLKKNIEKGVNFVASK
                     "
     gene            <280509..>280859
                     /gene="HOT13"
                     /locus_tag="YKL084W"
                     /db_xref="GeneID:853778"
     mRNA            <280509..>280859
                     /gene="HOT13"
                     /locus_tag="YKL084W"
                     /product="Hot13p"
                     /transcript_id="NM_001179650.1"
                     /db_xref="GI:296146294"
                     /db_xref="GeneID:853778"
     CDS             280509..280859
                     /gene="HOT13"
                     /locus_tag="YKL084W"
                     /note="Zinc-binding mitochondrial intermembrane space
                     (IMS) protein; involved in a disulfide relay system for
                     IMS import of cysteine-containing proteins; binds Mia40p
                     and stimulates its Erv1p-dependent oxidation, probably by
                     sequestering zinc"
                     /codon_start=1
                     /product="Hot13p"
                     /protein_id="NP_012839.1"
                     /db_xref="GI:6322766"
                     /db_xref="SGD:S000001567"
                     /db_xref="GeneID:853778"
                     /translation="MIETAIYGKTVDDQSRCVHWHLPKDVIAIRFKCCDKYYACFECH
                     QELSSHPLEKYDLLDDANKHLIICGVCRHEMTFAEYYDYNSNLICPNCRSPFNPGCKL
                     HYHLYFQNPPPAMC"
     gene            complement(<281025..>282329)
                     /gene="RRP14"
                     /locus_tag="YKL082C"
                     /db_xref="GeneID:853780"
     mRNA            complement(<281025..>282329)
                     /gene="RRP14"
                     /locus_tag="YKL082C"
                     /product="Rrp14p"
                     /transcript_id="NM_001179648.1"
                     /db_xref="GI:296146295"
                     /db_xref="GeneID:853780"
     CDS             complement(281025..282329)
                     /gene="RRP14"
                     /locus_tag="YKL082C"
                     /note="Essential protein, constituent of 66S pre-ribosomal
                     particles; interacts with proteins involved in ribosomal
                     biogenesis and cell polarity; member of the SURF-6 family"
                     /codon_start=1
                     /product="Rrp14p"
                     /protein_id="NP_012841.1"
                     /db_xref="GI:6322768"
                     /db_xref="SGD:S000001565"
                     /db_xref="GeneID:853780"
                     /translation="MSNSLEERLRANSSAFDGLLALIPAKYYYDEKSQEQWKAKKKTK
                     EQSKNDKLKKLDPEQRDDETSSTLEVMKKKEKDAKPVVLPGEKFKHMKMQKQKEATSK
                     VEGDSDLNVEVNDPMIIAPDEDEEEEEDIKVIFDDEGNEIPLESKKDTTEPDRSVEKK
                     SITEEEKLQRKKNLEALRSKLQAKISDMKSKRKAPGSREAILAQRKRKEELKKRKRLE
                     SEQEQDQDEIASDSDMEDIDSDLENNSKKRFKKGKKDSEINADGVMFQNIIFDDGARA
                     TSDLQRLRKAGRTKGPAKNDVKSHLKLLEAKKNKMEAKDELEQIKQKEKEKWQKAMLQ
                     AEGIKIRDDEKLLRKAIKRKEAQKRKSAIEWSERKRVVEDTISERQKRREENLRIRKD
                     NKGKKRNKQEKMKRKYVGSAVPKKRAGFEGRLKTGKKKGGPK"
     STS             282762..282894
                     /standard_name="px-61c1"
                     /db_xref="UniSTS:258034"
     gene            <282891..>284455
                     /gene="TEF4"
                     /locus_tag="YKL081W"
                     /gene_synonym="EFC1"
                     /db_xref="GeneID:853781"
     mRNA            join(<282891..283095,283422..>284455)
                     /gene="TEF4"
                     /locus_tag="YKL081W"
                     /gene_synonym="EFC1"
                     /product="Tef4p"
                     /transcript_id="NM_001179647.1"
                     /db_xref="GI:296146296"
                     /db_xref="GeneID:853781"
     CDS             join(282891..283095,283422..284455)
                     /gene="TEF4"
                     /locus_tag="YKL081W"
                     /gene_synonym="EFC1"
                     /note="Gamma subunit of translational elongation factor
                     eEF1B; stimulates the binding of aminoacyl-tRNA (AA-tRNA)
                     to ribosomes by releasing eEF1A (Tef1p/Tef2p) from the
                     ribosomal complex"
                     /codon_start=1
                     /product="Tef4p"
                     /protein_id="NP_012842.1"
                     /db_xref="GI:6322769"
                     /db_xref="SGD:S000001564"
                     /db_xref="GeneID:853781"
                     /translation="MSQGTLYINRSPRNYASEALISYFKLDVKIVDLEQSSEFASLFP
                     LKQAPAFLGPKGLKLTEALAIQFYLANQVADEKERARLLGSDVIEKSQILRWASLANS
                     DVMSNIARPFLSFKGLIPYNKKDVDACFVKIDNLAAVFDARLRDYTFVATENISLGDL
                     HAAGSWAFGLATILGPEWRAKHPHLMRWFNTVAASPIVKTPFAEVKLAEKALTYTPPK
                     KQKAEKPKAEKSKAEKKKDEAKPADDAAPAKKPKHPLEALGKSTFVLDDWKRKYSNDD
                     TRPVALPWFWEHYNPEEYSIWKVGYKYNDELTLTFMSNNLVGGFFNRLSASTKYMFGC
                     LVVYGENNNNGIVGAVMVRGQDFAPAFDVAPDWESYEYTKLDPTKEEDKEFVNNMWAW
                     DKPVVVNGEDKEIVDGKVLK"
     gene            283185..283279
                     /locus_tag="snR38"
                     /db_xref="GeneID:9164913"
     ncRNA           283185..283279
                     /locus_tag="snR38"
                     /ncRNA_class="snoRNA"
                     /product="SNR38"
                     /note="C/D box small nucleolar RNA (snoRNA); guides
                     2'-O-methylation of large subunit (LSU) rRNA at position
                     G2815"
                     /transcript_id="NR_132200.1"
                     /db_xref="GI:831416125"
                     /db_xref="SGD:S000007301"
                     /db_xref="GeneID:9164913"
     gene            <285030..>286208
                     /gene="VMA5"
                     /locus_tag="YKL080W"
                     /gene_synonym="CSL5; VAT3"
                     /db_xref="GeneID:853782"
     mRNA            <285030..>286208
                     /gene="VMA5"
                     /locus_tag="YKL080W"
                     /gene_synonym="CSL5; VAT3"
                     /product="H(+)-transporting V1 sector ATPase subunit C"
                     /transcript_id="NM_001179646.1"
                     /db_xref="GI:296146297"
                     /db_xref="GeneID:853782"
     CDS             285030..286208
                     /gene="VMA5"
                     /locus_tag="YKL080W"
                     /gene_synonym="CSL5; VAT3"
                     /note="Subunit C of the V1 peripheral membrane domain of
                     V-ATPase; part of the electrogenic proton pump found
                     throughout the endomembrane system; required for the V1
                     domain to assemble onto the vacuolar membrane; the V1
                     peripheral membrane domain of vacuolar H+-ATPase
                     (V-ATPase) has eight subunits"
                     /codon_start=1
                     /product="H(+)-transporting V1 sector ATPase subunit C"
                     /protein_id="NP_012843.1"
                     /db_xref="GI:6322770"
                     /db_xref="SGD:S000001563"
                     /db_xref="GeneID:853782"
                     /translation="MATALYTANDFILISLPQNAQPVTAPGSKTDSWFNETLIGGRAF
                     VSDFKIPEFKIGSLDTLIVESEELSKVDNQIGASIGKIIEILQGLNETSTNAYRTLPI
                     NNMPVPEYLENFQWQTRKFKLDKSIKDLITLISNESSQLDADVRATYANYNSAKTNLA
                     AAERKKTGDLSVRSLHDIVKPEDFVLNSEHLTTVLVAVPKSLKSDFEKSYETLSKNVV
                     PASASVIAEDAEYVLFNVHLFKKNVQEFTTAAREKKFIPREFNYSEELIDQLKKEHDS
                     AASLEQSLRVQLVRLAKTAYVDVFINWFHIKALRVYVESVLRYGLPPHFNIKIIAVPP
                     KNLSKCKSELIDAFGFLGGNAFMKDKKGKINKQDTSLHQYASLVDTEYEPFVMYIINL
                     "
     gene            <286603..>288573
                     /gene="SMY1"
                     /locus_tag="YKL079W"
                     /db_xref="GeneID:853783"
     mRNA            <286603..>288573
                     /gene="SMY1"
                     /locus_tag="YKL079W"
                     /product="Smy1p"
                     /transcript_id="NM_001179645.1"
                     /db_xref="GI:296146298"
                     /db_xref="GeneID:853783"
     CDS             286603..288573
                     /gene="SMY1"
                     /locus_tag="YKL079W"
                     /note="Kinesin-like myosin passenger-protein; interacts
                     with Myo2p; controls actin cable structure and dynamics;
                     proposed to be involved in exocytosis"
                     /codon_start=1
                     /product="Smy1p"
                     /protein_id="NP_012844.1"
                     /db_xref="GI:6322771"
                     /db_xref="SGD:S000001562"
                     /db_xref="GeneID:853783"
                     /translation="MHWNIISKEQSSSSVSLPTLDSSEPCHIEVILRAIPEKGLQNNE
                     STFKIDPYENTVLFRTNNPLHETTKETHSTFQFDKVFDANATQEDVQKFLVHPIINDV
                     LNGYNGTVITYGPSFSGKSYSLIGSKESEGILPNICKTLFDTLEKNEETKGDSFSVSV
                     LAFEIYMEKTYDLLVPLPERKPLKLHRSSSKMDLEIKDICPAHVGSYEDLRSYIQAVQ
                     NVGNRMACGDKTERSRSHLVFQLHVEQRNRKDDILKNSSLYLVDLHGAEKFDKRTEST
                     LSQDALKKLNQSIEALKNTVRSLSMKERDSAYSAKGSHSSAYRESQLTEVLKDSLGGN
                     RKTKVILTCFLSNVPTTLSTLEFGDSIRQINNKVTDNTTGLNLKKKMDLFIQDMKIKD
                     DNYVAQINILKAEIDSLKSLHNKSLPEDDEKKMLENTKKENIKLKLQLDSITQLLSSS
                     TNEDPNNRIDEEVSEILTKRCEQIAQLELSFDRQMNSNSKLQQELEYKKSKEEALESM
                     NVRLLEQIQLQEREIQELLTTNAILKGELETHTKLTETRSERIKSLESSVKELSLNKS
                     AIPSPRRGSMSSSSGNTMLHIEEGSEISNSPWSANTSSKPLVWGARKVSSSSIATTGS
                     QESFVARPFKKGLNLHSIKVTSSTPKSPSSGS"
     gene            <288845..>291052
                     /gene="DHR2"
                     /locus_tag="YKL078W"
                     /db_xref="GeneID:853784"
     mRNA            <288845..>291052
                     /gene="DHR2"
                     /locus_tag="YKL078W"
                     /product="Dhr2p"
                     /transcript_id="NM_001179644.1"
                     /db_xref="GI:296146299"
                     /db_xref="GeneID:853784"
     CDS             288845..291052
                     /gene="DHR2"
                     /locus_tag="YKL078W"
                     /EC_number="3.6.4.13"
                     /note="Predominantly nucleolar DEAH-box ATP-dependent RNA
                     helicase; required for 18S rRNA synthesis"
                     /codon_start=1
                     /product="Dhr2p"
                     /protein_id="NP_012845.1"
                     /db_xref="GI:6322772"
                     /db_xref="SGD:S000001561"
                     /db_xref="GeneID:853784"
                     /translation="MAANSNSRVASNHTSKKQKVRRNIHPFTNNTRIKRASKIVKFND
                     SGEGDHVSDQRSNKENVLTYKSLKSRASDLLKMRETLPVYQHKREIMSYIESNPVTVL
                     IGETGSGKSTQIPQFVLEKLYDTKKHGSIAVTQPRRVAAINLATRVAQEHGCKLGEQV
                     GYSVRFDNTTTTRTRLKYLTDGMLLRELMMNSDLREYSVIVIDEAHERTVLTDLILGF
                     LKSLIQGPRPDLRIIVMSATLQAEKFSEFFNNAPILFVEGRKFDVKQYYLKAPTDDIV
                     DAVIRCCIQINQGEELGDILCFLPGQEEIDKAVTIMEKIAKYVSDEAPVPLIVPYPLY
                     AALPAVQQSLVFAPIKGFKRKVVFSTNIAETSVTISGVKFVVDSGLRKVKVWRHQLGL
                     ATLLTVPISQASAMQRSGRAGRESEGKSFRLYCESDYVKLPKQSEPEIARSDVTSPVL
                     MLKRYGVDDLLNWTWFENPGKEAIVMGLQELYELGALDTRGKITKRGQQMALLPLQPH
                     LSSVLIKASEVGCLSQVIDIVSCLSVENLLLNPSPEERDEVNERRLSLCNAGKRYGDL
                     IMLKELFDIYFYELGKSQDASSERNDWCKGLCISIRGFKNVIRVRDQLRVYCKRLFSS
                     ISEEDEESKKIGEDGELISKILKCFLTGFIKNTAIGMPDRSYRTVSTGEPISIHPSSM
                     LFMNKSCPGIMYTEYVFTTKGYARNVSRIELSWLQEVVTNAAAVAKQKVSDSK"
     gene            <291453..>292631
                     /locus_tag="YKL077W"
                     /db_xref="GeneID:853785"
     mRNA            <291453..>292631
                     /locus_tag="YKL077W"
                     /product="hypothetical protein"
                     /transcript_id="NM_001179643.1"
                     /db_xref="GI:296146300"
                     /db_xref="GeneID:853785"
     CDS             291453..292631
                     /locus_tag="YKL077W"
                     /note="hypothetical protein; green fluorescent protein
                     (GFP)-fusion protein localizes to the vacuole"
                     /codon_start=1
                     /product="hypothetical protein"
                     /protein_id="NP_012846.1"
                     /db_xref="GI:6322773"
                     /db_xref="SGD:S000001560"
                     /db_xref="GeneID:853785"
                     /translation="MRFHDSILIFFSLASLYQHVHGARQVVRPKEKMTTSEEVKPWLR
                     TVYGSQKELVTPTVIAGVTFSEKPEETPNPLKPWVSLEHDGRPKTIKPEINKGRTKKG
                     RPDYSTYFKTVSSHTYSYEELKAHNMGPNEVFVEEEYIDEDDTYVSLNPIVRCTPNLY
                     FNKGLAKDIRSEPFCTPYENSRWKVDKTYFVTWYTRFFTDENSGKVADKVRVHLSYVK
                     ENPVEKGNYKRDIPATFFSSEWIDNDNGLMPVEVRDEWLQDQFDRRIVVSVQPIYISD
                     EDFDPLQYGILLYITKGSKVFKPTKEQLALDDAGITNDQWYYVALSIPTVVVVFFVFM
                     YFFLYVNGKNRDFTDVTRKALNKKRRVLGKFSEMKKFKNMKNHKYTELPSYKKTSKQN
                     "
     gene            complement(<292956..>294308)
                     /locus_tag="YKL075C"
                     /db_xref="GeneID:853787"
     mRNA            complement(<292956..>294308)
                     /locus_tag="YKL075C"
                     /product="hypothetical protein"
                     /transcript_id="NM_001179641.1"
                     /db_xref="GI:296146301"
                     /db_xref="GeneID:853787"
     CDS             complement(292956..294308)
                     /locus_tag="YKL075C"
                     /note="hypothetical protein; green fluorescent protein
                     (GFP)-fusion protein localizes to the cytoplasm; proposed
                     to be involved in resistance to streptozotocin and
                     camptothecin"
                     /codon_start=1
                     /product="hypothetical protein"
                     /protein_id="NP_012848.1"
                     /db_xref="GI:6322775"
                     /db_xref="SGD:S000001558"
                     /db_xref="GeneID:853787"
                     /translation="MAKDLLPKQAANEPSLKDCTCKRCLKLGASKEKKIRRKKKGEEK
                     RERHYGNRRKLTFNFLKHTNMENTNYDVITSVGYLNEKYGLKKSHYIEKFIKCIHRKI
                     NIDVSKITDAYVNSLNPWVKVKLFLLLVTLSEKGGPEYWLDKTDGEKNSEASSTDNSL
                     ENSTKGADSAGSTALRDEMVKSHKNLFPTLTEQIIQHNINQDFTESTYDEDYVFSSIW
                     ANFMEGLINHYLEKVIVPYSEMKVCQQLYKPMMKIISLYNEYNELMVKSEKNGFLPSL
                     QDSENVQGDKGEKESKDDAVSQERLERAQKLLWQAREDIPKTISKELTLLSEMYSTLS
                     ADEQDYELDEFVCCAEEYIELEYLPALVDVLFANCGTNNFWKIMLVLEPFFYYIEDVG
                     GDDDEDEDNVDNSEGDEESLLSRNVEGDDNVVERHFKPDPRVITLEKICEVAARQKWI
                     "
     gene            complement(<294610..>296193)
                     /gene="MUD2"
                     /locus_tag="YKL074C"
                     /db_xref="GeneID:853788"
     mRNA            complement(<294610..>296193)
                     /gene="MUD2"
                     /locus_tag="YKL074C"
                     /product="Mud2p"
                     /transcript_id="NM_001179640.1"
                     /db_xref="GI:296146302"
                     /db_xref="GeneID:853788"
     CDS             complement(294610..296193)
                     /gene="MUD2"
                     /locus_tag="YKL074C"
                     /note="Protein involved in early pre-mRNA splicing;
                     component of the pre-mRNA-U1 snRNP complex, the commitment
                     complex; interacts with Msl5p/BBP splicing factor and
                     Sub2p; similar to metazoan splicing factor U2AF65"
                     /codon_start=1
                     /product="Mud2p"
                     /protein_id="NP_012849.1"
                     /db_xref="GI:6322776"
                     /db_xref="SGD:S000001557"
                     /db_xref="GeneID:853788"
                     /translation="MADEKRLEDLRSKIMESIGKSEKDVVPIENKRFNTDNAVIDTHF
                     KRQKSDGELPKAPKSRNVSHSNNRGPSSIITMSTNRTTYEQTRAGPHRQSYRDASGRS
                     YNRENRYSSHNTGPQWNNNPYNRQRDERRGRNERFDRRGRNGNGNYDRFNYQRKNEGS
                     KFNGDRDKRQLQTNKYDMNYNSQNVMYPGSSFDSPAYYNMASSKANSRLVISGLSQSS
                     DPSIVARLKDLLENFISGLQKTESNAEDFKISNFYIGEGRPDHIIVEFSSQICSTMVL
                     ACRSFFNAKLGTFDLKWRRPNDYVQQLDHLVDFCRGTVIALENLENIGEGEDYRMKEL
                     FSSLNVTNGTAKPLFYKCSSNTNNTGKESEFTKCILLSFEVVTQDILDKLKPYKWFKP
                     NDGKISQVTSWITFQSLPNLVTQSVRVESRVLLLLNCLDPLDLKDETFITEIKETLKY
                     SIAGADTIKICQPGVDYRLNFENLASGAGNIYIKFKTLEAAKHAMEELPGTQFNDRTV
                     LCTYIDEDDFDMMEATQLS"
     gene            <296430..>299075
                     /gene="LHS1"
                     /locus_tag="YKL073W"
                     /gene_synonym="CER1; SSI1"
                     /db_xref="GeneID:853789"
     mRNA            <296430..>299075
                     /gene="LHS1"
                     /locus_tag="YKL073W"
                     /gene_synonym="CER1; SSI1"
                     /product="Hsp70 family chaperone LHS1"
                     /transcript_id="NM_001179639.1"
                     /db_xref="GI:296146303"
                     /db_xref="GeneID:853789"
     CDS             296430..299075
                     /gene="LHS1"
                     /locus_tag="YKL073W"
                     /gene_synonym="CER1; SSI1"
                     /EC_number="3.6.1.3"
                     /note="Molecular chaperone of the endoplasmic reticulum
                     lumen; involved in polypeptide translocation and folding;
                     nucleotide exchange factor for the ER lumenal Hsp70
                     chaperone Kar2p; regulated by the unfolded protein
                     response pathway"
                     /codon_start=1
                     /product="Hsp70 family chaperone LHS1"
                     /protein_id="NP_012850.1"
                     /db_xref="GI:6322777"
                     /db_xref="SGD:S000001556"
                     /db_xref="GeneID:853789"
                     /translation="MRNVLRLLFLTAFVAIGSLAAVLGVDYGQQNIKAIVVSPQAPLE
                     LVLTPEAKRKEISGLSIKRLPGYGKDDPNGIERIYGSAVGSLATRFPQNTLLHLKPLL
                     GKSLEDETTVTLYSKQHPGLEMVSTNRSTIAFLVDNVEYPLEELVAMNVQEIANRANS
                     LLKDRDARTEDFVNKMSFTIPDFFDQHQRKALLDASSITTGIEETYLVSEGMSVAVNF
                     VLKQRQFPPGEQQHYIVYDMGSGSIKASMFSILQPEDTTQPVTIEFEGYGYNPHLGGA
                     KFTMDIGSLIENKFLETHPAIRTDELHANPKALAKINQAAEKAKLILSANSEASINIE
                     SLINDIDFRTSITRQEFEEFIADSLLDIVKPINDAVTKQFGGYGTNLPEINGVILAGG
                     SSRIPIVQDQLIKLVSEEKVLRNVNADESAVNGVVMRGIKLSNSFKTKPLNVVDRSVN
                     TYSFKLSNESELYDVFTRGSAYPNKTSILTNTTDSIPNNFTIDLFENGKLFETITVNS
                     GAIKNSYSSDKCSSGVAYNITFDLSSDRLFSIQEVNCICQSENDIGNSKQIKNKGSRL
                     AFTSEDVEIKRLSPSERSRLHEHIKLLDKQDKERFQFQENLNVLESNLYDARNLLMDD
                     EVMQNGPKSQVEELSEMVKVYLDWLEDASFDTDPEDIVSRIREIGILKKKIELYMDSA
                     KEPLNSQQFKGMLEEGHKLLQAIETHKNTVEEFLSQFETEFADTIDNVREEFKKIKQP
                     AYVSKALSTWEETLTSFKNSISEIEKFLAKNLFGEDLREHLFEIKLQFDMYRTKLEEK
                     LRLIKSGDESRLNEIKKLHLRNFRLQKRKEEKLKRKLEQEKSRNNNETESTVINSADD
                     KTTIVNDKTTESNPSSEEDILHDEL"
     gene            <299582..>301882
                     /gene="STB6"
                     /locus_tag="YKL072W"
                     /db_xref="GeneID:853790"
     mRNA            <299582..>301882
                     /gene="STB6"
                     /locus_tag="YKL072W"
                     /product="Stb6p"
                     /transcript_id="NM_001179638.1"
                     /db_xref="GI:296146304"
                     /db_xref="GeneID:853790"
     CDS             299582..301882
                     /gene="STB6"
                     /locus_tag="YKL072W"
                     /note="Protein that binds Sin3p in a two-hybrid assay;
                     STB6 has a paralog, STB2, that arose from the whole genome
                     duplication"
                     /codon_start=1
                     /product="Stb6p"
                     /protein_id="NP_012851.1"
                     /db_xref="GI:6322778"
                     /db_xref="SGD:S000001555"
                     /db_xref="GeneID:853790"
                     /translation="MQLEATHQKENHLSPLASFIFPDFRALFNIGFNLYSNINYKEVD
                     INGFEIYIVEQWAAQRKISTLITSYTGNLQDTISAVEVALPEDPEEWPCCLKKYHEEL
                     LKFSSPKKTAKGTLFVTNLSSFKSTLNLLHVECGNLKKIWKNFKTNYDLKRLHCGGRS
                     AQLLKKTPSASIAKFAQLYKFPNSAFSHEITSDFQQPSLQNDNSSISSIENIPVNHCP
                     VVELTTLVQISLSYFALFEYKKERDGLLCNGTKQSLEKWWEIYGKRYHGIDKPKNETI
                     LGPTTVASLLSLVLTCYFKLMVEDCMSAKDPFDEEEFYSGLYAFQKKYGLSKNNKQTS
                     LDELTIDKLFEVSSKTSNKDIFKFKKVVKSTVQDMTGKGNFMHLSNEILTTDLDTLVK
                     NIHGGSLGKLWKGRSASRKETCMVWERKTFLSFKFERGDPSLQLENNELFYGTSVPSE
                     QLTTSNKEDSDTQPTKRNSIYDIANGSKSSLSISSMFCNYDETRYKSTNNLNRAYRGE
                     YFRRNSIPFCNDGIHDTKKISADLNKIDGLYRCNSYSEVQNAIELWSLPFDSSVIRLA
                     RDLLKIQSLMSVQRQLDEIRDGYLGKNSQRSYQNDLMFRQSLNKLQEMCERCKRGSNE
                     FHWEYGNMQNKQQILESEKKDMKSLSSKLKYNVRILDRRVRDVEASVDHFDRKLEDVR
                     KKLLEQNNSKDISMALESPCDKFEFDSFMDSIVQSQQTKYEGLCFKILDKKSLRKLKK
                     EFWKWSTWTFDTFLYKNRPNKEKDTL"
     LTR             complement(302334..302625)
                     /note="Ty1 LTR"
                     /db_xref="SGD:S000007052"
     gene            302918..303023
                     /locus_tag="tW(CCA)K"
                     /db_xref="GeneID:853791"
     tRNA            join(302918..302953,302988..303023)
                     /locus_tag="tW(CCA)K"
                     /product="tRNA-Trp"
                     /note="Tryptophan tRNA (tRNA-Trp), predicted by
                     tRNAscan-SE analysis"
                     /db_xref="SGD:S000006774"
                     /db_xref="GeneID:853791"
     gene            <305114..>305884
                     /locus_tag="YKL071W"
                     /db_xref="GeneID:853792"
     mRNA            <305114..>305884
                     /locus_tag="YKL071W"
                     /product="hypothetical protein"
                     /transcript_id="NM_001179637.1"
                     /db_xref="GI:296146305"
                     /db_xref="GeneID:853792"
     CDS             305114..305884
                     /locus_tag="YKL071W"
                     /note="hypothetical protein; expression induced in cells
                     treated with the mycotoxin patulin, and also the quinone
                     methide triterpene celastrol; green fluorescent protein
                     (GFP)-fusion protein localizes to the cytoplasm"
                     /codon_start=1
                     /product="hypothetical protein"
                     /protein_id="NP_012852.1"
                     /db_xref="GI:6322779"
                     /db_xref="SGD:S000001554"
                     /db_xref="GeneID:853792"
                     /translation="MNTSSRITYFIIGGSRGIGFNLVKILSASTGNTVITSIRGSPSL
                     PKNKQVEDLAKIRKNIHIVQLDLTKDESIGNIADEIKKTPFFLGIDIFIACSAVSDSY
                     YKVLETPKSVWLNHYSTNALGPILALQKVYPLLLLKKTRKIFFISSVAGSINAFVPLS
                     VSAYGQSKAALNYAVKTLSFELKPEGFTVVAFHPGMVSTDMGQYGLDHFKEKNIDISG
                     VNIITPEESASALIDVFRKILPEDNGKFFNYDGSEGVF"
     gene            <306211..>306720
                     /locus_tag="YKL070W"
                     /db_xref="GeneID:853793"
     mRNA            <306211..>306720
                     /locus_tag="YKL070W"
                     /product="hypothetical protein"
                     /transcript_id="NM_001179636.1"
                     /db_xref="GI:296146306"
                     /db_xref="GeneID:853793"
     CDS             306211..306720
                     /locus_tag="YKL070W"
                     /note="hypothetical protein; expression induced in cells
                     treated with mycotoxins patulin or citrinin; the
                     authentic, non-tagged protein is detected in highly
                     purified mitochondria in high-throughput studies"
                     /codon_start=1
                     /product="hypothetical protein"
                     /protein_id="NP_012853.1"
                     /db_xref="GI:6322780"
                     /db_xref="SGD:S000001553"
                     /db_xref="GeneID:853793"
                     /translation="MYIPKHFESMELSRYKLSKKPPLGTLFSSKASRQGFFGWRTSSN
                     KDDPDFGMCASHIPFVFVEFDNGEHKLIAHLARKNKHVEMLERVQKCLVVFQSVDSYI
                     SPAWFPMKKKTHKFVPTWDFAAVHVYGTPRIIRDDKDWLINMLSTLTDQEEEKRPEGE
                     NVRSKVERF"
     gene            <307285..>307827
                     /locus_tag="YKL069W"
                     /gene_synonym="YKG9"
                     /db_xref="GeneID:853794"
     mRNA            <307285..>307827
                     /locus_tag="YKL069W"
                     /gene_synonym="YKG9"
                     /product="hypothetical protein"
                     /transcript_id="NM_001179635.1"
                     /db_xref="GI:296146307"
                     /db_xref="GeneID:853794"
     CDS             307285..307827
                     /locus_tag="YKL069W"
                     /gene_synonym="YKG9"
                     /EC_number="1.8.4.14"
                     /note="Methionine-R-sulfoxide reductase; reduces the R
                     enantiomer of free Met-SO, in contrast to Ycl033Cp which
                     reduces Met-R-SO in a peptide linkage; has a role in
                     protection against oxidative stress; relative distribution
                     to the nucleus increases upon DNA replication stress"
                     /codon_start=1
                     /product="hypothetical protein"
                     /protein_id="NP_012854.1"
                     /db_xref="GI:6322781"
                     /db_xref="SGD:S000001552"
                     /db_xref="GeneID:853794"
                     /translation="MGSSTGFHHADHVNYSSNLNKEEILEQLLLSYEGLSDGQVNWVC
                     NLSNASSLIWHAYKSLAVDINWAGFYVTQASEENTLILGPFQGKVACQMIQFGKGVCG
                     TAASTKETQIVPDVNKYPGHIACDGETKSEIVVPIISNDGKTLGVIDIDCLDYEGFDH
                     VDKEFLEKLAKLINKSCVFK"
     gene            complement(308144..308217)
                     /locus_tag="tV(AAC)K1"
                     /db_xref="GeneID:853795"
     tRNA            complement(308144..308217)
                     /locus_tag="tV(AAC)K1"
                     /product="tRNA-Val"
                     /note="Valine tRNA (tRNA-Val), predicted by tRNAscan-SE
                     analysis"
                     /db_xref="SGD:S000006760"
                     /db_xref="GeneID:853795"
     gene            <309206..>309442
                     /locus_tag="YKL068W-A"
                     /db_xref="GeneID:1500487"
     mRNA            <309206..>309442
                     /locus_tag="YKL068W-A"
                     /product="hypothetical protein"
                     /transcript_id="NM_001184534.1"
                     /db_xref="GI:296146308"
                     /db_xref="GeneID:1500487"
     CDS             309206..309442
                     /locus_tag="YKL068W-A"
                     /note="hypothetical protein; identified by homology to
                     Ashbya gossypii"
                     /codon_start=1
                     /product="hypothetical protein"
                     /protein_id="NP_878111.1"
                     /db_xref="GI:33578048"
                     /db_xref="SGD:S000028524"
                     /db_xref="GeneID:1500487"
                     /translation="MQANHSVSYLYESSTSKRSNGLFSQTQKQGSFQKALSQTQEEIE
                     DEDLMVDLNTGSLTPVKLKYWTQMSAMTEKFGKL"
     gene            <310199..>313078
                     /gene="NUP100"
                     /locus_tag="YKL068W"
                     /gene_synonym="NSP100"
                     /db_xref="GeneID:853796"
     mRNA            <310199..>313078
                     /gene="NUP100"
                     /locus_tag="YKL068W"
                     /gene_synonym="NSP100"
                     /product="FG-nucleoporin NUP100"
                     /transcript_id="NM_001179634.1"
                     /db_xref="GI:296146309"
                     /db_xref="GeneID:853796"
     CDS             310199..313078
                     /gene="NUP100"
                     /locus_tag="YKL068W"
                     /gene_synonym="NSP100"
                     /note="FG-nucleoporin component of central core of the
                     nuclear pore complex; contributes directly to
                     nucleocytoplasmic transport and maintenance of the nuclear
                     pore complex (NPC) permeability barrier and is involved in
                     gene tethering at the nuclear periphery; NUP100 has a
                     paralog, NUP116, that arose from the whole genome
                     duplication"
                     /codon_start=1
                     /product="FG-nucleoporin NUP100"
                     /protein_id="NP_012855.1"
                     /db_xref="GI:6322782"
                     /db_xref="SGD:S000001551"
                     /db_xref="GeneID:853796"
                     /translation="MFGNNRPMFGGSNLSFGSNTSSFGGQQSQQPNSLFGNSNNNNNS
                     TSNNAQSGFGGFTSAAGSNSNSLFGNNNTQNNGAFGQSMGATQNSPFGSLNSSNASNG
                     NTFGGSSSMGSFGGNTNNAFNNNSNSTNSPFGFNKPNTGGTLFGSQNNNSAGTSSLFG
                     GQSTSTTGTFGNTGSSFGTGLNGNGSNIFGAGNNSQSNTTGSLFGNQQSSAFGTNNQQ
                     GSLFGQQSQNTNNAFGNQNQLGGSSFGSKPVGSGSLFGQSNNTLGNTTNNRNGLFGQM
                     NSSNQGSSNSGLFGQNSMNSSTQGVFGQNNNQMQINGNNNNSLFGKANTFSNSASGGL
                     FGQNNQQQGSGLFGQNSQTSGSSGLFGQNNQKQPNTFTQSNTGIGLFGQNNNQQQQST
                     GLFGAKPAGTTGSLFGGNSSTQPNSLFGTTNVPTSNTQSQQGNSLFGATKLTNMPFGG
                     NPTANQSGSGNSLFGTKPASTTGSLFGNNTASTTVPSTNGLFGNNANNSTSTTNTGLF
                     GAKPDSQSKPALGGGLFGNSNSNSSTIGQNKPVFGGTTQNTGLFGATGTNSSAVGSTG
                     KLFGQNNNTLNVGTQNVPPVNNTTQNALLGTTAVPSLQQAPVTNEQLFSKISIPNSIT
                     NPVKATTSKVNADMKRNSSLTSAYRLAPKPLFAPSSNGDAKFQKWGKTLERSDRGSST
                     SNSITDPESSYLNSNDLLFDPDRRYLKHLVIKNNKNLNVINHNDDEASKVKLVTFTTE
                     SASKDDQASSSIAASKLTEKAHSPQTDLKDDHDESTPDPQSKSPNGSTSIPMIENEKI
                     SSKVPGLLSNDVTFFKNNYYISPSIETLGNKSLIELRKINNLVIGHRNYGKVEFLEPV
                     DLLNTPLDTLCGDLVTFGPKSCSIYENCSIKPEKGEGINVRCRVTLYSCFPIDKETRK
                     PIKNITHPLLKRSIAKLKENPVYKFESYDPVTGTYSYTIDHPVLT"
     gene            complement(313401..313472)
                     /locus_tag="tH(GUG)K"
                     /db_xref="GeneID:853797"
     tRNA            complement(313401..313472)
                     /locus_tag="tH(GUG)K"
                     /product="tRNA-His"
                     /note="Histidine tRNA (tRNA-His), predicted by tRNAscan-SE
                     analysis"
                     /db_xref="SGD:S000006598"
                     /db_xref="GeneID:853797"
     LTR             complement(313602..313919)
                     /note="Ty1 LTR"
                     /db_xref="SGD:S000007053"
     LTR             314193..314524
                     /note="Ty1 LTR"
                     /db_xref="SGD:S000007057"
     gene            <314812..>315273
                     /gene="YNK1"
                     /locus_tag="YKL067W"
                     /gene_synonym="NDK1"
                     /db_xref="GeneID:853798"
     mRNA            <314812..>315273
                     /gene="YNK1"
                     /locus_tag="YKL067W"
                     /gene_synonym="NDK1"
                     /product="nucleoside diphosphate kinase"
                     /transcript_id="NM_001179633.1"
                     /db_xref="GI:296146310"
                     /db_xref="GeneID:853798"
     CDS             314812..315273
                     /gene="YNK1"
                     /locus_tag="YKL067W"
                     /gene_synonym="NDK1"
                     /EC_number="2.7.4.6"
                     /note="Nucleoside diphosphate kinase; catalyzes the
                     transfer of gamma phosphates from nucleoside
                     triphosphates, usually ATP, to nucleoside diphosphates by
                     a mechanism that involves formation of an
                     autophosphorylated enzyme intermediate; protein abundance
                     increases in response to DNA replication stress"
                     /codon_start=1
                     /product="nucleoside diphosphate kinase"
                     /protein_id="NP_012856.1"
                     /db_xref="GI:6322783"
                     /db_xref="SGD:S000001550"
                     /db_xref="GeneID:853798"
                     /translation="MSSQTERTFIAVKPDGVQRGLVSQILSRFEKKGYKLVAIKLVKA
                     DDKLLEQHYAEHVGKPFFPKMVSFMKSGPILATVWEGKDVVRQGRTILGATNPLGSAP
                     GTIRGDFGIDLGRNVCHGSDSVDSAEREINLWFKKEELVDWESNQAKWIYE"
     gene            <315954..>316175
                     /locus_tag="YKL065W-A"
                     /db_xref="GeneID:3799975"
     mRNA            <315954..>316175
                     /locus_tag="YKL065W-A"
                     /product="hypothetical protein"
                     /transcript_id="NM_001184684.1"
                     /db_xref="GI:296146311"
                     /db_xref="GeneID:3799975"
     CDS             315954..316175
                     /locus_tag="YKL065W-A"
                     /codon_start=1
                     /product="hypothetical protein"
                     /protein_id="NP_001032580.1"
                     /db_xref="GI:82795257"
                     /db_xref="SGD:S000113563"
                     /db_xref="GeneID:3799975"
                     /translation="MRSNILKLLQRTSRRYVSSKDFEPVIGSNPKKQTSRLMVGSVGV
                     MIPVLLYLFYKNDSKHSEIKKIYQNEKKI"
     gene            complement(<316437..>317057)
                     /gene="YET1"
                     /locus_tag="YKL065C"
                     /db_xref="GeneID:853800"
     mRNA            complement(<316437..>317057)
                     /gene="YET1"
                     /locus_tag="YKL065C"
                     /product="Yet1p"
                     /transcript_id="NM_001179631.2"
                     /db_xref="GI:330443653"
                     /db_xref="GeneID:853800"
     CDS             complement(316437..317057)
                     /gene="YET1"
                     /locus_tag="YKL065C"
                     /note="Endoplasmic reticulum transmembrane protein; may
                     interact with ribosomes, based on co-purification
                     experiments; homolog of human BAP31 protein; YET1 has a
                     paralog, YET2, that arose from the whole genome
                     duplication"
                     /codon_start=1
                     /product="Yet1p"
                     /protein_id="NP_012858.2"
                     /db_xref="GI:330443654"
                     /db_xref="SGD:S000001548"
                     /db_xref="GeneID:853800"
                     /translation="MSLYFTTLFLLLTVEMVMLFIFVLPLPFRIRRGIFSTYNQLTAK
                     QQIKTIIFITGCLVGLLFIDSWKRSQIRVSLYHNDNSGSIGSSAVTPIQALASRAYNQ
                     RNMYISGFILYFSICIPTVMSIVKRLVKYQGLINEQEKQKLNKPSSNSKKDSNEADST
                     KLQEELRKKQISLEGLQKQVKNLEKYFDEKNQPGNVAAAEASKKGN"
     gene            <317764..>320673
                     /gene="MNR2"
                     /locus_tag="YKL064W"
                     /db_xref="GeneID:853801"
     mRNA            <317764..>320673
                     /gene="MNR2"
                     /locus_tag="YKL064W"
                     /product="putative Mg(2+) transporter MNR2"
                     /transcript_id="NM_001179630.1"
                     /db_xref="GI:296146313"
                     /db_xref="GeneID:853801"
     CDS             317764..320673
                     /gene="MNR2"
                     /locus_tag="YKL064W"
                     /note="Vacuolar membrane protein required for magnesium
                     homeostasis; putative magnesium transporter; has
                     similarity to Alr1p and Alr2p, which mediate influx of
                     Mg2+ and other divalent cations"
                     /codon_start=1
                     /product="putative Mg(2+) transporter MNR2"
                     /protein_id="NP_012859.1"
                     /db_xref="GI:6322786"
                     /db_xref="SGD:S000001547"
                     /db_xref="GeneID:853801"
                     /translation="MSTDNSQKDEGVPLLSPYSSSPQLRKKKRNQKRRKDKFVGHLKS
                     DSRRPTQLLHDNLQHNHGQITDFDQIDSWGMLHESDSTSNDIIKSEDPSLKGAFIDHR
                     PSMSQPREGPQSVSSTVQPQPIMKFSTPSYKKPAGLRPSDQNRSLVSDLSPSELESWL
                     KRRKSVHKSFVDENSPTDRRQSNANNDVVIDVDALMNHVNNNASTGVNDNSKRRKKKR
                     GSDDSSNKNSKSTSSDSNDEEDEYNSRPSSSLSSNNSSLDDVCLVLDDEGSEVPKAWP
                     DCTVLEEFSKEETERLRSQAIQDAEAFHFQYDEDEEDGTSNEDGILFSKPIVTNIDVP
                     ELGNRRVNETENLKNGRLRPKRIAPWHLIQRPMVLGSNSTKDSKSRIQSGLQDNLLVG
                     RNIQYPPHIISNNPEHFRFTYFRVDLDSTVHSPTISGLLQPGQKFQDLFVASIYSQDN
                     SAGHIKTHPNSPTPGIKAETVSQLQGLTAKNPSTLSSMSVANIEDVPPFWLDVSNPTE
                     EEMKILSKAFGIHPLTTEDIFLGEVREKVELFRDYYLICFRSFDIVAEKHVRRRRKEK
                     QESATLDHESISRRKSQAYGATMSNESNANNNNSTSNASRSKWLPSILRARRRSSANR
                     TTNTSSSSYKRRVKSEKKKMEENEKFKRKSGDRHKPREGELEPLNVYIIVFRTGVLTF
                     HFAPTPHPINVRRRARLLKDYLNVTSDWIAYALIDDITDAFAPMIELIEDEVYEIEDA
                     ILKMHQSDDSSDSDSSDSDSDSGASDEDAFPFDVYSKKTSYSSAKSSVSSRSMSTSEA
                     SFNANLIGWKRKGDMLRRIGECRKRVMSILRLLGSKADVIKGFAKRYNEQWEASPQSE
                     IAMYLGDIQDHIVTMVSSLNHYEKLLSRSHSNYLAQINIDMTKVNNDMNDVLGKITIL
                     GTIVLPMNVITGLWGMNVIVPGQYRDSLTWFIGIVLFMCMLACSAYMYTKRRFGF"
     gene            complement(<321015..>321518)
                     /locus_tag="YKL063C"
                     /db_xref="GeneID:853802"
     mRNA            complement(<321015..>321518)
                     /locus_tag="YKL063C"
                     /product="hypothetical protein"
                     /transcript_id="NM_001179629.1"
                     /db_xref="GI:296146314"
                     /db_xref="GeneID:853802"
     CDS             complement(321015..321518)
                     /locus_tag="YKL063C"
                     /note="hypothetical protein; green fluorescent protein
                     (GFP)-fusion protein localizes to the Golgi"
                     /codon_start=1
                     /product="hypothetical protein"
                     /protein_id="NP_012860.1"
                     /db_xref="GI:6322787"
                     /db_xref="SGD:S000001546"
                     /db_xref="GeneID:853802"
                     /translation="MQGDIRRKKDLLPRYKTGSKYNSRRRGGYLTTPMKKIIVYIILL
                     CGVYFVIKVAYSDLNKETEIKLESHSSDVSASASDHTNIAAGGAADATNNKQPQQAKV
                     PKEKFNNEVAKQQEVKNLENDLKPQIDSEKQKQINKDKKEQKQQLQKEKQDLAKENLA
                     NNEILDN"
     gene            <323228..>325120
                     /gene="MSN4"
                     /locus_tag="YKL062W"
                     /db_xref="GeneID:853803"
     mRNA            <323228..>325120
                     /gene="MSN4"
                     /locus_tag="YKL062W"
                     /product="stress-responsive transcriptional activator
                     MSN4"
                     /transcript_id="NM_001179628.1"
                     /db_xref="GI:296146315"
                     /db_xref="GeneID:853803"
     CDS             323228..325120
                     /gene="MSN4"
                     /locus_tag="YKL062W"
                     /note="Stress-responsive transcriptional activator;
                     activated in stochastic pulses of nuclear localization in
                     response to various stress conditions; binds DNA at stress
                     response elements of responsive genes, inducing gene
                     expression; involved in diauxic shift"
                     /codon_start=1
                     /product="stress-responsive transcriptional activator
                     MSN4"
                     /protein_id="NP_012861.1"
                     /db_xref="GI:6322788"
                     /db_xref="SGD:S000001545"
                     /db_xref="GeneID:853803"
                     /translation="MLVFGPNSSFVRHANKKQEDSSIMNEPNGLMDPVLSTTNVSATS
                     SNDNSANNSISSPEYTFGQFSMDSPHRTDATNTPILTATTNTTANNSLMNLKDTASLA
                     TNWKWKNSNNAQFVNDGEKQSSNANGKKNGGDKIYSSVATPQALNDELKNLEQLEKVF
                     SPMNPINDSHFNENIELSPHQHATSPKTNLLEAEPSIYSNLFLDARLPNNANSTTGLN
                     DNDYNLDDTNNDNTNSMQSILEDFVSSEEALKFMPDAGRDARRYSEVVTSSFPSMTDS
                     RNSISHSIEFWNLNHKNSSNSKPTQQIIPEGTATTERRGSTISPTTTINNSNPNFKLL
                     DHDVSQALSGYSMDFSKDSGITKPKSISSSLNRISHSSSTTRQQRASLPLIHDIESFA
                     NDSVMANPLSDSASFLSEENEDDAFGALNYNSLDATTMSAFDNNVDPFNILKSSPAQD
                     QQFIKPSMMLSDNASAAAKLATSGVDNITPTPAFQRRSYDISMNSSFKILPTSQAHHA
                     AQHHQQQPTKQATVSPNTRRRKSSSVTLSPTISHNNNNGKVPVQPRKRKSITTIDPNN
                     YDKNKPFKCKDCEKAFRRSEHLKRHIRSVHSTERPFACMFCEKKFSRSDNLSQHLKTH
                     KKHGDF"
     gene            <325771..>326112
                     /gene="BLI1"
                     /locus_tag="YKL061W"
                     /db_xref="GeneID:853804"
     mRNA            <325771..>326112
                     /gene="BLI1"
                     /locus_tag="YKL061W"
                     /product="Bli1p"
                     /transcript_id="NM_001179627.1"
                     /db_xref="GI:296146316"
                     /db_xref="GeneID:853804"
     CDS             325771..326112
                     /gene="BLI1"
                     /locus_tag="YKL061W"
                     /note="Subunit of the BLOC-1 complex involved in endosomal
                     maturation; interacts with Msb3p; green fluorescent
                     protein (GFP)-fusion protein localizes to the endosome"
                     /codon_start=1
                     /product="Bli1p"
                     /protein_id="NP_012862.1"
                     /db_xref="GI:6322789"
                     /db_xref="SGD:S000001544"
                     /db_xref="GeneID:853804"
                     /translation="MGEQNKLYYDVEKLVNSLQESFDLDCAQSVSLFTSKSRSNEAWL
                     EELENKFKLKDDVELDDVENLRAEIDMKLNMLEDKVSYYERLYKELEEFQNEIKIKTV
                     VNNRRQSRTPK"
     gene            complement(<326408..>327487)
                     /gene="FBA1"
                     /locus_tag="YKL060C"
                     /gene_synonym="LOT1"
                     /db_xref="GeneID:853805"
     mRNA            complement(<326408..>327487)
                     /gene="FBA1"
                     /locus_tag="YKL060C"
                     /gene_synonym="LOT1"
                     /product="fructose-bisphosphate aldolase FBA1"
                     /transcript_id="NM_001179626.1"
                     /db_xref="GI:296146317"
                     /db_xref="GeneID:853805"
     CDS             complement(326408..327487)
                     /gene="FBA1"
                     /locus_tag="YKL060C"
                     /gene_synonym="LOT1"
                     /EC_number="4.1.2.13"
                     /note="Fructose 1,6-bisphosphate aldolase; required for
                     glycolysis and gluconeogenesis; catalyzes conversion of
                     fructose 1,6 bisphosphate to glyceraldehyde-3-P and
                     dihydroxyacetone-P; locates to mitochondrial outer surface
                     upon oxidative stress; N-terminally propionylated in vivo"
                     /codon_start=1
                     /product="fructose-bisphosphate aldolase FBA1"
                     /protein_id="NP_012863.1"
                     /db_xref="GI:6322790"
                     /db_xref="SGD:S000001543"
                     /db_xref="GeneID:853805"
                     /translation="MGVEQILKRKTGVIVGEDVHNLFTYAKEHKFAIPAINVTSSSTA
                     VAALEAARDSKSPIILQTSNGGAAYFAGKGISNEGQNASIKGAIAAAHYIRSIAPAYG
                     IPVVLHSDHCAKKLLPWFDGMLEADEAYFKEHGEPLFSSHMLDLSEETDEENISTCVK
                     YFKRMAAMDQWLEMEIGITGGEEDGVNNENADKEDLYTKPEQVYNVYKALHPISPNFS
                     IAAAFGNCHGLYAGDIALRPEILAEHQKYTREQVGCKEEKPLFLVFHGGSGSTVQEFH
                     TGIDNGVVKVNLDTDCQYAYLTGIRDYVLNKKDYIMSPVGNPEGPEKPNKKFFDPRVW
                     VREGEKTMGAKITKSLETFRTTNTL"
     gene            complement(<328118..>329443)
                     /gene="MPE1"
                     /locus_tag="YKL059C"
                     /db_xref="GeneID:853806"
     mRNA            complement(<328118..>329443)
                     /gene="MPE1"
                     /locus_tag="YKL059C"
                     /product="Mpe1p"
                     /transcript_id="NM_001179625.1"
                     /db_xref="GI:296146318"
                     /db_xref="GeneID:853806"
     CDS             complement(328118..329443)
                     /gene="MPE1"
                     /locus_tag="YKL059C"
                     /note="Essential conserved subunit of CPF cleavage and
                     polyadenylation factor; plays a role in 3' end formation
                     of mRNA via the specific cleavage and polyadenylation of
                     pre-mRNA; contains a ubiquitin-like (UBL) domain, a
                     RNA-binding zinc knuckle motif and a RING finger domain;
                     both the zinc knuckle and RING finger are required for
                     pre-mRNA binding; possible role in ubiquitination of
                     Pap1p; relocalizes to the cytosol in response to hypoxia"
                     /codon_start=1
                     /product="Mpe1p"
                     /protein_id="NP_012864.1"
                     /db_xref="GI:6322791"
                     /db_xref="SGD:S000001542"
                     /db_xref="GeneID:853806"
                     /translation="MSSTIFYRFKSQRNTSRILFDGTGLTVFDLKREIIQENKLGDGT
                     DFQLKIYNPDTEEEYDDDAFVIPRSTSVIVKRSPAIKSFSVHSRLKGNVGAAALGNAT
                     RYVTGRPRVLQKRQHTATTTANVSGTTEEERIASMFATQENQWEQTQEEMSAATPVFF
                     KSQTNKNSAQENEGPPPPGYMCYRCGGRDHWIKNCPTNSDPNFEGKRIRRTTGIPKKF
                     LKSIEIDPETMTPEEMAQRKIMITDEGKFVVQVEDKQSWEDYQRKRENRQIDGDETIW
                     RKGHFKDLPDDLKCPLTGGLLRQPVKTSKCCNIDFSKEALENALVESDFVCPNCETRD
                     ILLDSLVPDQDKEKEVETFLKKQEELHGSSKDGNQPETKKMKLMDPTGTAGLNNNTSL
                     PTSVNNGGTPVPPVPLPFGIPPFPMFPMPFMPPTATITNPHQADASPKK"
     rep_origin      329682..329930
                     /note="ARS1109;
                     Autonomously Replicating Sequence"
                     /db_xref="SGD:S000118403"
     gene            <330166..>330534
                     /gene="TOA2"
                     /locus_tag="YKL058W"
                     /db_xref="GeneID:853807"
     mRNA            <330166..>330534
                     /gene="TOA2"
                     /locus_tag="YKL058W"
                     /product="TFIIA subunit gamma"
                     /transcript_id="NM_001179624.1"
                     /db_xref="GI:296146319"
                     /db_xref="GeneID:853807"
     CDS             330166..330534
                     /gene="TOA2"
                     /locus_tag="YKL058W"
                     /note="TFIIA small subunit; involved in transcriptional
                     activation, acts as antirepressor or as coactivator;
                     required, along with Toa1p, for ribosomal protein gene
                     transcription in vivo; homologous to smallest subunit of
                     human and Drosophila TFIIA; protein abundance increases in
                     response to DNA replication stress"
                     /codon_start=1
                     /product="TFIIA subunit gamma"
                     /protein_id="NP_012865.1"
                     /db_xref="GI:6322792"
                     /db_xref="SGD:S000001541"
                     /db_xref="GeneID:853807"
                     /translation="MAVPGYYELYRRSTIGNSLVDALDTLISDGRIEASLAMRVLETF
                     DKVVAETLKDNTQSKLTVKGNLDTYGFCDDVWTFIVKNCQVTVEDSHRDASQNGSGDS
                     QSVISVDKLRIVACNSKKSE"
     gene            complement(<330856..>333969)
                     /gene="NUP120"
                     /locus_tag="YKL057C"
                     /gene_synonym="RAT2"
                     /db_xref="GeneID:853808"
     mRNA            complement(<330856..>333969)
                     /gene="NUP120"
                     /locus_tag="YKL057C"
                     /gene_synonym="RAT2"
                     /product="Nup120p"
                     /transcript_id="NM_001179623.1"
                     /db_xref="GI:296146320"
                     /db_xref="GeneID:853808"
     CDS             complement(330856..333969)
                     /gene="NUP120"
                     /locus_tag="YKL057C"
                     /gene_synonym="RAT2"
                     /note="Subunit of the Nup84p subcomplex of the nuclear
                     pore complex (NPC); contributes to nucleocytoplasmic
                     transport and NPC biogenesis and is involved in
                     establishment of a normal nucleocytoplasmic concentration
                     gradient of the GTPase Gsp1p; also plays roles in several
                     processes that may require localization of genes or
                     chromosomes at the nuclear periphery, including
                     double-strand break repair, transcription and chromatin
                     silencing; homologous to human NUP160"
                     /codon_start=1
                     /product="Nup120p"
                     /protein_id="NP_012866.1"
                     /db_xref="GI:6322793"
                     /db_xref="SGD:S000001540"
                     /db_xref="GeneID:853808"
                     /translation="MACLSRIDANLLQYYEKPEPNNTVDLYVSNNSNNNGLKEGDKSI
                     STPVPQPYGSEYSNCLLLSNSEYICYHFSSRSTLLTFYPLSDAYHGKTINIHLPNASM
                     NQRYTLTIQEVEQQLLVNVILKDGSFLTLQLPLSFLFSSANTLNGEWFHLQNPYDFTV
                     RVPHFLFYVSPQFSVVFLEDGGLLGLKKVDGVHYEPLLFNDNSYLKSLTRFFSRSSKS
                     DYDSVISCKLFHERYLIVLTQNCHLKIWDLTSFTLIQDYDMVSQSDSDPSHFRKVEAV
                     GEYLSLYNNTLVTLLPLENGLFQMGTLLVDSSGILTYTFQNNIPTNLSASAIWSIVDL
                     VLTRPLELNVEASYLNLIVLWKSGTASKLQILNVNDESFKNYEWIESVNKSLVDLQSE
                     HDLDIVTKTGDVERGFCNLKSRYGTQIFERAQQILSENKIIMAHNEDEEYLANLETIL
                     RDVKTAFNEASSITLYGDEIILVNCFQPYNHSLYKLNTTVENWFYNMHSETDGSELFK
                     YLRTLNGFASTLSNDVLRSISKKFLDIITGELPDSMTTVEKFTDIFKNCLENQFEITN
                     LKILFDELNSFDIPVVLNDLINNQMKPGIFWKKDFISAIKFDGFTSIISLESLHQLLS
                     IHYRITLQVLLTFVLFDLDTEIFGQHISTLLDLHYKQFLLLNLYRQDKCLLAEVLLKD
                     SSEFSFGVKFFNYGQLIAYIDSLNSNVYNASITENSFFMTFFRSYIIENTSHKNIRFF
                     LENVECPFYLRHNEVQEFMFAMTLFSCGNFDQSYEIFQLHDYPEAINDKLPTFLEDLK
                     SENYHGDSIWKDLLCTFTVPYRHSAFYYQLSLLFDRNNSQEFALKCISKSAEYSLKEI
                     QIEELQDFKEKQHIHYLNLLIHFRMFEEVLDVLRLGHECLSDTVRTNFLQLLLQEDIY
                     SRDFFSTLLRLCNAHSDNGELYLRTVDIKIVDSILSQNLRSGDWECFKKLYCFRMLNK
                     SERAAAEVLYQYILMQADLDVIRKRKCYLMVINVLSSFDSAYDQWILNGSKVVTLTDL
                     RDELRGL"
     gene            complement(<334412..>334915)
                     /gene="TMA19"
                     /locus_tag="YKL056C"
                     /gene_synonym="MMI1"
                     /db_xref="GeneID:853809"
     mRNA            complement(<334412..>334915)
                     /gene="TMA19"
                     /locus_tag="YKL056C"
                     /gene_synonym="MMI1"
                     /product="Tma19p"
                     /transcript_id="NM_001179622.1"
                     /db_xref="GI:296146321"
                     /db_xref="GeneID:853809"
     CDS             complement(334412..334915)
                     /gene="TMA19"
                     /locus_tag="YKL056C"
                     /gene_synonym="MMI1"
                     /note="Protein that associates with ribosomes; homolog of
                     translationally controlled tumor protein; green
                     fluorescent protein (GFP)-fusion protein localizes to the
                     cytoplasm and relocates to the mitochondrial outer surface
                     upon oxidative stress"
                     /codon_start=1
                     /product="Tma19p"
                     /protein_id="NP_012867.1"
                     /db_xref="GI:6322794"
                     /db_xref="SGD:S000001539"
                     /db_xref="GeneID:853809"
                     /translation="MIIYKDIFSNDELLSDAYDAKLVDDVIYEADCAMVNVGGDNIDI
                     GANPSAEGGDDDVEEGAEMVNNVVHSFRLQQTAFDKKSFLTYIKGYMKAVKAKLQETN
                     PEEVPKFEKGAQTYVKKVIGSFKDWEFFTGESMDPDAMVVMLNYREDGTTPFVAIWKH
                     GIVEEKI"
     gene            complement(<335321..>336157)
                     /gene="OAR1"
                     /locus_tag="YKL055C"
                     /db_xref="GeneID:853810"
     mRNA            complement(<335321..>336157)
                     /gene="OAR1"
                     /locus_tag="YKL055C"
                     /product="3-oxoacyl-[acyl-carrier-protein] reductase
                     (NADPH)"
                     /transcript_id="NM_001179621.2"
                     /db_xref="GI:330443655"
                     /db_xref="GeneID:853810"
     CDS             complement(335321..336157)
                     /gene="OAR1"
                     /locus_tag="YKL055C"
                     /EC_number="1.1.1.100"
                     /note="Mitochondrial 3-oxoacyl-[acyl-carrier-protein]
                     reductase; may comprise a type II mitochondrial fatty acid
                     synthase along with Mct1p"
                     /codon_start=1
                     /product="3-oxoacyl-[acyl-carrier-protein] reductase
                     (NADPH)"
                     /protein_id="NP_012868.1"
                     /db_xref="GI:6322795"
                     /db_xref="SGD:S000001538"
                     /db_xref="GeneID:853810"
                     /translation="MHYLPVAIVTGATRGIGKAICQKLFQKGLSCIILGSTKESIERT
                     AIDRGQLQSGLSYQRQCAIAIDFKKWPHWLDYESYDGIEYFKDRPPLKQKYSTLFDPC
                     NKWSNNERRYYVNLLINCAGLTQESLSVRTTASQIQDIMNVNFMSPVTMTNICIKYMM
                     KSQRRWPELSGQSARPTIVNISSILHSGKMKVPGTSVYSASKAALSRFTEVLAAEMEP
                     RNIRCFTISPGLVKGTDMIQNLPVEAKEMLERTIGASGTSAPAEIAEEVWSLYSRTAL
                     ET"
     gene            complement(<336537..>338753)
                     /gene="DEF1"
                     /locus_tag="YKL054C"
                     /gene_synonym="VID31"
                     /db_xref="GeneID:853811"
     mRNA            complement(<336537..>338753)
                     /gene="DEF1"
                     /locus_tag="YKL054C"
                     /gene_synonym="VID31"
                     /product="DNA damage-responsive RNA polymerase-degradation
                     factor DEF1"
                     /transcript_id="NM_001179620.1"
                     /db_xref="GI:296146323"
                     /db_xref="GeneID:853811"
     CDS             complement(336537..338753)
                     /gene="DEF1"
                     /locus_tag="YKL054C"
                     /gene_synonym="VID31"
                     /note="RNAPII degradation factor; forms a complex with
                     Rad26p in chromatin, enables ubiquitination and
                     proteolysis of RNAPII present in an elongation complex;
                     mutant is deficient in Zip1p loading onto chromosomes
                     during meiosis"
                     /codon_start=1
                     /product="DNA damage-responsive RNA polymerase-degradation
                     factor DEF1"
                     /protein_id="NP_012869.1"
                     /db_xref="GI:6322796"
                     /db_xref="SGD:S000001537"
                     /db_xref="GeneID:853811"
                     /translation="MSTQFRKSNHNSHSSKKLNPALKSKIDTLTELFPDWTSDDLIDI
                     VQEYDDLETIIDKITSGAVTRWDEVKKPAKKEKYEKKEQQHSYVPQQHLPNPEDDITY
                     KSSNNSNSFTSTKHNSSNNYTQARNKKKVQTPRAHTTGKHVNLDKGKHVPSKPVSNTT
                     SWAAAVSVDTKHDVPQDSNDNNNEELEAQGQQAQEKNQEKEQEEQQQQEGHNNKEEHK
                     QIEQPSLSSKKTTSRTSASQPKKMSWAAIATPKPKAVKKTESPLENVAELKKEISDIK
                     KDDQKSEASEEKVNEQETSAQEQEEETAEPSEENEDRVPEVDGEEVQEEAEKKEQVKE
                     EEQTAEELEQEQDNVAAPEEEVTVVEEKVEISAVISEPPEDQANTVPQPQQQSQQPQQ
                     PQQPQQPQQPQQPQQQQQPQQPQQPQQQLQQQQQQQQQPVQAQAQAQEEQLSQNYYTQ
                     QQQQQYAQQQHQLQQQYLSQQQQYAQQQQQHPQPQSQQPQSQQSPQSQKQGNNVAAQQ
                     YYMYQNQFPGYSYPGMFDSQGYAYGQQYQQLAQNNAQTSGNANQYNFQQGYGQAGANT
                     AAANLTSAAAAAAASPATAHAQPQQQQPYGGSFMPYYAHFYQQSFPYGQPQYGVAGQY
                     PYQLPKNNYNYYQTQNGQEQQSPNQGVAQHSEDSQQKQSQQQQQQQPQGQPQPEVQMQ
                     NGQPVNPQQQMQFQQYYQFQQQQQQAAAAAAAAAQQGVPYGYNGYDYNSKNSRGFY"
     gene            complement(<339182..>339442)
                     /gene="MDM35"
                     /locus_tag="YKL053C-A"
                     /db_xref="GeneID:853812"
     mRNA            complement(<339182..>339442)
                     /gene="MDM35"
                     /locus_tag="YKL053C-A"
                     /product="Mdm35p"
                     /transcript_id="NM_001184336.1"
                     /db_xref="GI:296146324"
                     /db_xref="GeneID:853812"
     CDS             complement(339182..339442)
                     /gene="MDM35"
                     /locus_tag="YKL053C-A"
                     /note="Mitochondrial intermembrane space protein; mutation
                     affects mitochondrial distribution and morphology;
                     contains twin cysteine-x9-cysteine motifs; protein
                     abundance increases in response to DNA replication stress"
                     /codon_start=1
                     /product="Mdm35p"
                     /protein_id="NP_012870.1"
                     /db_xref="GI:6322797"
                     /db_xref="SGD:S000007243"
                     /db_xref="GeneID:853812"
                     /translation="MGNIMSASFAPECTDLKTKYDSCFNEWYSEKFLKGKSVENECSK
                     QWYAYTTCVNAALVKQGIKPALDEAREEAPFENGGKLKEVDK"
     gene            complement(<339668..>340546)
                     /gene="ASK1"
                     /locus_tag="YKL052C"
                     /db_xref="GeneID:853814"
     mRNA            complement(<339668..>340546)
                     /gene="ASK1"
                     /locus_tag="YKL052C"
                     /product="Ask1p"
                     /transcript_id="NM_001179618.1"
                     /db_xref="GI:296146325"
                     /db_xref="GeneID:853814"
     CDS             complement(339668..340546)
                     /gene="ASK1"
                     /locus_tag="YKL052C"
                     /note="Essential subunit of the Dam1 complex (aka DASH
                     complex); couples kinetochores to the force produced by MT
                     depolymerization thereby aiding in chromosome segregation;
                     phosphorylated during the cell cycle by cyclin-dependent
                     kinases; sumoylated in an Mms21p-dependent manner; protein
                     abundance increases in response to DNA replication stress"
                     /codon_start=1
                     /product="Ask1p"
                     /protein_id="NP_012872.2"
                     /db_xref="GI:269970311"
                     /db_xref="SGD:S000001535"
                     /db_xref="GeneID:853814"
                     /translation="MDSASKEETLEKLDQEITVNLQKIDSNLSFCFHKITQDIIPHVA
                     TYSEICERIMDSTEWLGTMFQETGLVNLQANAAAPVGNAPVKSLVSNNVGIFPTSAEE
                     ASRQSQTDNGPNEADSAVHVNRDVHSMFNNDSIDDFHTANITSTGQILKLPDSSDEDT
                     GSEAVPSREQTDLTGEGHGGADDEQDESTIQRQSRKRKISLLLQQQYGSSSSMVPSPI
                     VPNKMRKQLAHEEHINNDGDNDDENSNNIESSPLKQGHHHPKGQADDNNEGPDEEEST
                     KEVPKPGTIIHFSTNR"
     gene            <341312..>342373
                     /gene="SFK1"
                     /locus_tag="YKL051W"
                     /db_xref="GeneID:853815"
     mRNA            <341312..>342373
                     /gene="SFK1"
                     /locus_tag="YKL051W"
                     /product="Sfk1p"
                     /transcript_id="NM_001179617.1"
                     /db_xref="GI:296146326"
                     /db_xref="GeneID:853815"
     CDS             341312..342373
                     /gene="SFK1"
                     /locus_tag="YKL051W"
                     /note="Plasma membrane protein that may act to generate
                     normal levels of PI4P; may act together with or upstream
                     of Stt4p; at least partially mediates proper localization
                     of Stt4p to the plasma membrane"
                     /codon_start=1
                     /product="Sfk1p"
                     /protein_id="NP_012873.1"
                     /db_xref="GI:6322800"
                     /db_xref="SGD:S000001534"
                     /db_xref="GeneID:853815"
                     /translation="MIQFKSPGNWLFIVPWIAFIPWYGMLIAMLICWASQGHPIYWFM
                     HSEQFPVYISDIGATNLRPLFISCAGWQGLGYVITVALEFFQRSGYLPFQLKKKDPSI
                     SDSTSYAEKLHSGKYLMPPYYTKDERNLIFAAFVLGSIGELALLFSSIFSTALYHRVH
                     IAMVSVFVVFMFLSTCCLIAEYFLMGRHYASVHPLASPHFNPQSSEKSFNQDYNTVDE
                     LPWYKWKGHVWNKFTISATLKVIWLTLAVVWAICFGAINDRSKSACFEWLLAFWFGII
                     FMILSADFYLGGRYRQSRYFNHVESFSGYYKYDKALGLYHSEDVLPSDDNAGVIATET
                     ASSNIYNNSSSNESIQVVV"
     gene            complement(<342852..>345620)
                     /locus_tag="YKL050C"
                     /db_xref="GeneID:853816"
     mRNA            complement(<342852..>345620)
                     /locus_tag="YKL050C"
                     /product="hypothetical protein"
                     /transcript_id="NM_001179616.1"
                     /db_xref="GI:296146327"
                     /db_xref="GeneID:853816"
     CDS             complement(342852..345620)
                     /locus_tag="YKL050C"
                     /note="hypothetical protein; the YKL050W protein is a
                     target of the SCFCdc4 ubiquitin ligase complex and YKL050W
                     transcription is regulated by Azf1p; YKL050C has a
                     paralog, EIS1, that arose from the whole genome
                     duplication"
                     /codon_start=1
                     /product="hypothetical protein"
                     /protein_id="NP_012874.1"
                     /db_xref="GI:6322801"
                     /db_xref="SGD:S000001533"
                     /db_xref="GeneID:853816"
                     /translation="MSLISALQTTDVESVQTSPEQITERKAVRVSTLQESLHSSEMHR
                     AAPETPRSISNSVHKLKTIYSTYQQSGQPLSKEAIFRAKQKYGILNTPANYKTLGLGD
                     SKSESVDLAARLASKRTKVSPDDCVETAIEQKARGEAFKVTFSKIPLTPPEDVPITVN
                     LGLKGRRDFLTRLAAQKALAFSPSLDNSMKGTSDSSSVKKKRFSGAPIGNEFDANLVN
                     PQHPAGFKSLDLSKVLDGAERRAISRVNDRLYPQKVNFKNGLQSSDQSGVSKANKEVF
                     KKGTLEKLEHSAEQFLESHAGNERQRLSDQQYMCAKGAADAVKDLDPKTLEDPDFAAR
                     EAQKKLYIKQVASPVVLNEAQKLANRKLQDIDSRDTYMLLFGNQAYNKLAVNIALQHY
                     SVKQEEKKKIYLGGGLWMTPEEVNAVAKKLISPVVNEIDERASRQRDVDKDIERRSRV
                     LDQEYEDGNSMERAKEQNDGQLLLAMASKQQQEKEAKKAEEGQRYDQFVQKMNIKLQQ
                     KEKELENARENRENLRNELQERLSKNLSGENDELNDWNDACERDLKNSSIEHYYAVRS
                     HFDNLGNSERGYDELLEERSKIQVEIERLVASIAEHKTAIHGFGETADAGGAIPAVQK
                     QKIPTRKDLLDATVNDPLVISAEMAKEEAEMATEECMLKELQVDEMIIIRNIMLRECE
                     KKLEEEKETAKRSRRGTEESKNNSNFSRDVIMSTPDNNEKVTPIGKSASPKDVVKSRF
                     LSTYNTGKDIDSSASARSITGVSGVLDDGPKTPTSNKENELIDDEVKSYKVHQAVDGT
                     GEDSIANKRDKSSRPAANSGGSITIEQFLFNKNADKQGLSKTESVTMKREPVVDQMDS
                     KKGHDFTHCNDNGRRSFSGFSQGSIENDYSNEVTDDQDDQEGSEIRVRDSNDSNTSPK
                     ESFFKEVI"
     gene            complement(<346075..>346764)
                     /gene="CSE4"
                     /locus_tag="YKL049C"
                     /gene_synonym="CSL2"
                     /db_xref="GeneID:853817"
     mRNA            complement(<346075..>346764)
                     /gene="CSE4"
                     /locus_tag="YKL049C"
                     /gene_synonym="CSL2"
                     /product="centromeric DNA-binding histone H3-like protein
                     CSE4"
                     /transcript_id="NM_001179615.1"
                     /db_xref="GI:296146328"
                     /db_xref="GeneID:853817"
     CDS             complement(346075..346764)
                     /gene="CSE4"
                     /locus_tag="YKL049C"
                     /gene_synonym="CSL2"
                     /note="Centromere protein that resembles histone H3;
                     associated with promoters, accessible chromatin and RNA
                     polymerase II-bound regions; phosphorylated Cse4p
                     associates with centromeres; required for proper
                     kinetochore function; levels regulated by E3 ubiquitin
                     ligase Psh1p; phosphorylation of Cse4p may destabilize
                     defective kinetochores to promote bi-orientation;
                     ubiquitination of N terminus regulates Cse4p proteolysis
                     for faithful chromosome segregation; human CENP-A homolog"
                     /codon_start=1
                     /product="centromeric DNA-binding histone H3-like protein
                     CSE4"
                     /protein_id="NP_012875.2"
                     /db_xref="GI:27808712"
                     /db_xref="SGD:S000001532"
                     /db_xref="GeneID:853817"
                     /translation="MSSKQQWVSSAIQSDSSGRSLSNVNRLAGDQQSINDRALSLLQR
                     TRATKNLFPRREERRRYESSKSDLDIETDYEDQAGNLEIETENEEEAEMETEVPAPVR
                     THSYALDRYVRQKRREKQRKQSLKRVEKKYTPSELALYEIRKYQRSTDLLISKIPFAR
                     LVKEVTDEFTTKDQDLRWQSMAIMALQEASEAYLVGLLEHTNLLALHAKRITIMKKDM
                     QLARRIRGQFI"
     gene            complement(<347214..>349136)
                     /gene="ELM1"
                     /locus_tag="YKL048C"
                     /gene_synonym="LDB9"
                     /db_xref="GeneID:853818"
     mRNA            complement(<347214..>349136)
                     /gene="ELM1"
                     /locus_tag="YKL048C"
                     /gene_synonym="LDB9"
                     /product="serine/threonine protein kinase ELM1"
                     /transcript_id="NM_001179614.1"
                     /db_xref="GI:296146329"
                     /db_xref="GeneID:853818"
     CDS             complement(347214..349136)
                     /gene="ELM1"
                     /locus_tag="YKL048C"
                     /gene_synonym="LDB9"
                     /EC_number="2.7.11.1"
                     /note="Serine/threonine protein kinase that regulates
                     cellular morphogenesis; septin behavior, and cytokinesis;
                     required for the regulation of other kinases, such as
                     Kin4p; forms part of the bud neck ring"
                     /codon_start=1
                     /product="serine/threonine protein kinase ELM1"
                     /protein_id="NP_012876.1"
                     /db_xref="GI:6322803"
                     /db_xref="SGD:S000001531"
                     /db_xref="GeneID:853818"
                     /translation="MSPRQLIPTLIPEWAPLSQQSCIREDELDSPPITPTSQTSSFGS
                     SFSQQKPTYSTIIGENIHTILDEIRPYVKKITVSDQDKKTINQYTLGVSAGSGQFGYV
                     RKAYSSTLGKVVAVKIIPKKPWNAQQYSVNQVMRQIQLWKSKGKITTNMSGNEAMRLM
                     NIEKCRWEIFAASRLRNNVHIVRLIECLDSPFSESIWIVTNWCSLGELQWKRDDDEDI
                     LPQWKKIVISNCSVSTFAKKILEDMTKGLEYLHSQGCIHRDIKPSNILLDEEEKVAKL
                     SDFGSCIFTPQSLPFSDANFEDCFQRELNKIVGTPAFIAPELCHLGNSKRDFVTDGFK
                     LDIWSLGVTLYCLLYNELPFFGENEFETYHKIIEVSLSSKINGNTLNDLVIKRLLEKD
                     VTLRISIQDLVKVLSRDQPIDSRNHSQISSSSVNPVRNEGPVRRFFGRLLTKKGKKKT
                     SGKGKDKVLVSATSKVTPSIHIDEEPDKECFSTTVLRSSPDSSDYCSSLGEEAIQVTD
                     FLDTFCRSNESLPNLTVNNDKQNSDMKTDRSESSSHSSLKIPTPIKAMIRLKSSPKEN
                     GNRTHINCSQDKPSSPLMDRTVGKRTVNNSGARKLAHSSNILNFKAYINSEDSDIRET
                     VEDVKTYLNFADNGQI"
     gene            <349463..>351013
                     /gene="ANR2"
                     /locus_tag="YKL047W"
                     /db_xref="GeneID:853819"
     mRNA            <349463..>351013
                     /gene="ANR2"
                     /locus_tag="YKL047W"
                     /product="Anr2p"
                     /transcript_id="NM_001179613.1"
                     /db_xref="GI:296146330"
                     /db_xref="GeneID:853819"
     CDS             349463..351013
                     /gene="ANR2"
                     /locus_tag="YKL047W"
                     /note="hypothetical protein; may have a role in lipid
                     metabolism, based on localization to lipid droplets;
                     predicted to be palmitoylated"
                     /codon_start=1
                     /product="Anr2p"
                     /protein_id="NP_012877.1"
                     /db_xref="GI:6322804"
                     /db_xref="SGD:S000001530"
                     /db_xref="GeneID:853819"
                     /translation="MNSGGEEPTIKPNVFNITQLLNSNGEKPGIACIFLSKFDMKKGN
                     IIIWSKSINGAAIDLSNIEFKSLPAGIHEQTDDVVNFVVPKELDVCQTAKTTTYDYGI
                     AYFKQNSFDIIENDNRIDRSKVQMFSLGVIIDVQNASSDSKKHFYKEIYHAYAANRYS
                     SYLESLLGQWIRQRDLDKFDIFEKFFDENNQGHMAENSVEVFEHSPKERRHLVEYLPY
                     WTRKLGPLIFPLWKASLLQSRILILVPQGESFELCNSLAYCVFLISMLPKNLIGNHVS
                     DEYIKPIFTVSTSDIPFLESFKKGNGYVATTSEEILLYKPEIYDIVVKLTSSSTIEES
                     PEKEVEILTASGEQNKATPLDLEVYEKLILGELQEDASTNATCRHHEVTEPISWLQFL
                     IDGFFLLTTAGYLVAPYHLANNFKIPRHVSGPEPNNSEIQIAENLVRYFHRRTSNLYN
                     DLKDVIQKSENIDSEQPITIAASFLTKLNLDCFSKQDHQFVKDIALKWFQRSIDISNL
                     PECLGNLC"
     gene            complement(<351275..>352624)
                     /gene="DCW1"
                     /locus_tag="YKL046C"
                     /db_xref="GeneID:853820"
     mRNA            complement(<351275..>352624)
                     /gene="DCW1"
                     /locus_tag="YKL046C"
                     /product="Dcw1p"
                     /transcript_id="NM_001179612.1"
                     /db_xref="GI:296146331"
                     /db_xref="GeneID:853820"
     CDS             complement(351275..352624)
                     /gene="DCW1"
                     /locus_tag="YKL046C"
                     /EC_number="3.2.1.101"
                     /note="Putative mannosidase; GPI-anchored membrane protein
                     required for cell wall biosynthesis in bud
                     formation;homologous to Dfg5p"
                     /codon_start=1
                     /product="Dcw1p"
                     /protein_id="NP_012878.1"
                     /db_xref="GI:6322805"
                     /db_xref="SGD:S000001529"
                     /db_xref="GeneID:853820"
                     /translation="MLVNKVIGLLGVLFATRFTNAVELDLDNYESLQNATSLIAYGLM
                     DYYTGNQYGKTVGMFSDPYYWWEAGGAWGCMLDYWFFMDNDTYNDEIIAAMIHQAGDD
                     NDYIPLNQSTTEGNDDQAFWGIAAMTAAERNFTNPPENEPQWLYLAQAVFNTMALRWD
                     ADSCGGGLRWQIFVWNSGYDYKNTVSNGALFHIAARLARYTGNQTYVDWAEKVYEWMV
                     GVNLISNGTYKYVYDGVSIDDNCTKVTSYQWTYNQGLLLAGSAYLYNFTGSDLWHTRT
                     KEFLNASQVFFHDGIVYEAACQGPNSCNTDQRSFKAYFARFLGVTAQLVPETRNQIMS
                     WLNTSAIAAAKSCSGGTDGHTCGLNWFNGTWDGMYGLGEQMSALEVMVNTRALDKPAP
                     YTAENGGSSVGDGAAGTQAQPTNLAPLNITKGSKAGAGIITAVIGISIVACALWLVF"
     gene            <353493..>355079
                     /gene="PRI2"
                     /locus_tag="YKL045W"
                     /db_xref="GeneID:853821"
     mRNA            <353493..>355079
                     /gene="PRI2"
                     /locus_tag="YKL045W"
                     /product="DNA primase subunit PRI2"
                     /transcript_id="NM_001179611.1"
                     /db_xref="GI:296146332"
                     /db_xref="GeneID:853821"
     CDS             353493..355079
                     /gene="PRI2"
                     /locus_tag="YKL045W"
                     /EC_number="2.7.7.-"
                     /note="Subunit of DNA primase; DNA primase is required for
                     DNA synthesis and double-strand break repair"
                     /codon_start=1
                     /product="DNA primase subunit PRI2"
                     /protein_id="NP_012879.1"
                     /db_xref="GI:6322806"
                     /db_xref="SGD:S000001528"
                     /db_xref="GeneID:853821"
                     /translation="MFRQSKRRIASRKNFSSYDDIVKSELDVGNTNAANQIILSSSSS
                     EEEKKLYARLYESKLSFYDLPPQGEITLEQFEIWAIDRLKILLEIESCLSRNKSIKEI
                     ETIIKPQFQKLLPFNTESLEDRKKDYYSHFILRLCFCRSKELREKFVRAETFLFKIRF
                     NMLTSTDQTKFVQSLDLPLLQFISNEEKAELSHQLYQTVSASLQFQLNLNEEHQRKQY
                     FQQEKFIKLPFENVIELVGNRLVFLKDGYAYLPQFQQLNLLSNEFASKLNQELIKTYQ
                     YLPRLNEDDRLLPILNHLSSGYTIADFNQQKANQFSENVDDEINAQSVWSEEISSNYP
                     LCIKNLMEGLKKNHHLRYYGRQQLSLFLKGIGLSADEALKFWSEAFTRNGNMTMEKFN
                     KEYRYSFRHNYGLEGNRINYKPWDCHTILSKPRPGRGDYHGCPFRDWSHERLSAELRS
                     MKLTQAQIISVLDSCQKGEYTIACTKVFEMTHNSASADLEIGEQTHIAHPNLYFERSR
                     QLQKKQQKLEKEKLFNNGNH"
     gene            <356322..>356642
                     /locus_tag="YKL044W"
                     /db_xref="GeneID:853822"
     mRNA            <356322..>356642
                     /locus_tag="YKL044W"
                     /product="hypothetical protein"
                     /transcript_id="NM_001270755.1"
                     /db_xref="GI:398364578"
                     /db_xref="GeneID:853822"
     CDS             356322..356642
                     /locus_tag="YKL044W"
                     /note="hypothetical protein; mRNA identified as translated
                     by ribosome profiling data"
                     /codon_start=1
                     /product="hypothetical protein"
                     /protein_id="NP_001257684.1"
                     /db_xref="GI:398364579"
                     /db_xref="SGD:S000001527"
                     /db_xref="GeneID:853822"
                     /translation="MGYVIMTFSSARMSERRARIIYIWMHLSAYKINFPFVQFPTFFS
                     LFRLQKKAAILIKNPSPFFLFFLFPYRKNSTARTIHQINQAVALVLLCVSHHLTYLPS
                     VPSL"
     gene            <356748..>357848
                     /gene="PHD1"
                     /locus_tag="YKL043W"
                     /db_xref="GeneID:853823"
     mRNA            <356748..>357848
                     /gene="PHD1"
                     /locus_tag="YKL043W"
                     /product="Phd1p"
                     /transcript_id="NM_001179609.1"
                     /db_xref="GI:296146333"
                     /db_xref="GeneID:853823"
     CDS             356748..357848
                     /gene="PHD1"
                     /locus_tag="YKL043W"
                     /note="Transcriptional activator that enhances
                     pseudohyphal growth; physically interacts with the
                     Tup1-Cyc8 complex and recruits Tup1p to its targets;
                     regulates expression of FLO11, an adhesin required for
                     pseudohyphal filament formation; similar to StuA, an A.
                     nidulans developmental regulator; potential Cdc28p
                     substrate; PHD1 has a paralog, SOK2, that arose from the
                     whole genome duplication"
                     /codon_start=1
                     /product="Phd1p"
                     /protein_id="NP_012881.1"
                     /db_xref="GI:6322808"
                     /db_xref="SGD:S000001526"
                     /db_xref="GeneID:853823"
                     /translation="MYHVPEMRLHYPLVNTQSNAAITPTRSYDNTLPSFNELSHQSTI
                     NLPFVQRETPNAYANVAQLATSPTQAKSGYYCRYYAVPFPTYPQQPQSPYQQAVLPYA
                     TIPNSNFQPSSFPVMAVMPPEVQFDGSFLNTLHPHTELPPIIQNTNDTSVARPNNLKS
                     IAAASPTVTATTRTPGVSSTSVLKPRVITTMWEDENTICYQVEANGISVVRRADNNMI
                     NGTKLLNVTKMTRGRRDGILRSEKVREVVKIGSMHLKGVWIPFERAYILAQREQILDH
                     LYPLFVKDIESIVDARKPSNKASLTPKSSPAPIKQEPSDNKHEIATEIKPKSIDALSN
                     GASTQGAGELPHLKINHIDTEAQTSRAKNELS"
     gene            <358475..>359566
                     /gene="SPC42"
                     /locus_tag="YKL042W"
                     /db_xref="GeneID:853824"
     mRNA            <358475..>359566
                     /gene="SPC42"
                     /locus_tag="YKL042W"
                     /product="Spc42p"
                     /transcript_id="NM_001179608.3"
                     /db_xref="GI:398364590"
                     /db_xref="GeneID:853824"
     CDS             358475..359566
                     /gene="SPC42"
                     /locus_tag="YKL042W"
                     /note="Central plaque component of spindle pole body
                     (SPB); involved in SPB duplication, may facilitate
                     attachment of the SPB to the nuclear membrane"
                     /codon_start=1
                     /product="Spc42p"
                     /protein_id="NP_012882.3"
                     /db_xref="GI:398364591"
                     /db_xref="SGD:S000001525"
                     /db_xref="GeneID:853824"
                     /translation="MNGSPTPKRYSSKSSRLYDDYYNIPYQYSNPTPMNRDYNDVGSR
                     INADKLVPEEYKRNTEFINKAVQQNKELNFKLREKQNEIFELKKIAETLRSKLEKYVD
                     ITKKLEDQNLNLQIKISDLEKKLSDANSTFKEMRFPKVKDPMVDDDPVSENYDQINVP
                     KHRAPDATGNPRTTNKVSNTSDQDSRLKAIERTLSVLTNYVMRSEDGNNDRMSPLPSP
                     LNTILPINNRLNFQEPKRYNPTVKVNPSDDDIMMYESAELKRVEEEIEELKRKILVRK
                     KHDLRKLSLNNQLQELQSMMDGDDNIKLDNVSKHNHATHRHSSQSSRDYSPSSDACLE
                     CSNDLYEKNRVKPENNMSETFATPTPNNR"
     gene            <360143..>360817
                     /gene="VPS24"
                     /locus_tag="YKL041W"
                     /gene_synonym="DID3; VPL26"
                     /db_xref="GeneID:853825"
     mRNA            <360143..>360817
                     /gene="VPS24"
                     /locus_tag="YKL041W"
                     /gene_synonym="DID3; VPL26"
                     /product="ESCRT-III subunit protein VPS24"
                     /transcript_id="NM_001179607.1"
                     /db_xref="GI:296146335"
                     /db_xref="GeneID:853825"
     CDS             360143..360817
                     /gene="VPS24"
                     /locus_tag="YKL041W"
                     /gene_synonym="DID3; VPL26"
                     /note="One of four subunits of the ESCRT-III complex;
                     forms an endosomal sorting complex required for transport
                     III (ESCRT-III) subcomplex with Did4p; involved in the
                     sorting of transmembrane proteins into the multivesicular
                     body (MVB) pathway"
                     /codon_start=1
                     /product="ESCRT-III subunit protein VPS24"
                     /protein_id="NP_012883.1"
                     /db_xref="GI:6322810"
                     /db_xref="SGD:S000001524"
                     /db_xref="GeneID:853825"
                     /translation="MDYIKKAIWGPDPKEQQRRIRSVLRKNGRNIEKSLRELTVLQNK
                     TQQLIKKSAKKNDVRTVRLYAKELYQINKQYDRMYTSRAQLDSVRMKIDEAIRMNTLS
                     NQMADSAGLMREVNSLVRLPQLRNTMIELEKELMKSGIISEMVDDTMESVGDVGEEMD
                     EAVDEEVNKIVEQYTNEKFKNVDQVPTVELAANEEEQEIPDEKVDEEADRMVNEMRER
                     LRALQN"
     gene            complement(<361058..>361828)
                     /gene="NFU1"
                     /locus_tag="YKL040C"
                     /gene_synonym="NUB1"
                     /db_xref="GeneID:853826"
     mRNA            complement(<361058..>361828)
                     /gene="NFU1"
                     /locus_tag="YKL040C"
                     /gene_synonym="NUB1"
                     /product="Nfu1p"
                     /transcript_id="NM_001179606.3"
                     /db_xref="GI:398364600"
                     /db_xref="GeneID:853826"
     CDS             complement(361058..361828)
                     /gene="NFU1"
                     /locus_tag="YKL040C"
                     /gene_synonym="NUB1"
                     /note="Protein involved in iron metabolism in
                     mitochondria; similar to NifU, which is a protein required
                     for the maturation of the Fe/S clusters of nitrogenase in
                     nitrogen-fixing bacteria"
                     /codon_start=1
                     /product="Nfu1p"
                     /protein_id="NP_012884.3"
                     /db_xref="GI:398364601"
                     /db_xref="SGD:S000001523"
                     /db_xref="GeneID:853826"
                     /translation="MFKSVAKLGKSPIFYLNSQRLIHIKTLTTPNENALKFLSTDGEM
                     LQTRGSKSIVIKNTDENLINHSKLAQQIFLQCPGVESLMIGDDFLTINKDRMVHWNSI
                     KPEIIDLLTKQLAYGEDVISKEFHAVQEEEGEGGYKINMPKFELTEEDEEVSELIEEL
                     IDTRIRPAILEDGGDIDYRGWDPKTGTVYLRLQGACTSCSSSEVTLKYGIESMLKHYV
                     DEVKEVIQIMDPEQEIALKEFDKLEKKLESSKNTSHEK"
     gene            <362622..>364193
                     /gene="PTM1"
                     /locus_tag="YKL039W"
                     /db_xref="GeneID:853827"
     mRNA            <362622..>364193
                     /gene="PTM1"
                     /locus_tag="YKL039W"
                     /product="Ptm1p"
                     /transcript_id="NM_001179605.1"
                     /db_xref="GI:296146337"
                     /db_xref="GeneID:853827"
     CDS             362622..364193
                     /gene="PTM1"
                     /locus_tag="YKL039W"
                     /note="hypothetical protein; copurifies with late Golgi
                     vesicles containing the v-SNARE Tlg2p; PTM1 has a paralog,
                     YHL017W, that arose from the whole genome duplication"
                     /codon_start=1
                     /product="Ptm1p"
                     /protein_id="NP_012885.2"
                     /db_xref="GI:83722565"
                     /db_xref="SGD:S000001522"
                     /db_xref="GeneID:853827"
                     /translation="MRVYQFCRPFQLFTCFLCYLLVFVKANKEKISQKNYQVCAGMYS
                     KEDWKGKIDPFISFNLKKISGLSDESDPGLVVAIYDFQDFEHLGVQLPDEEMYYICDD
                     YAIDIGICEEENRDEFIVQDVVYDPYTSTNRSLANPIMTFSQNEVGLHDTRYPIKETG
                     FYCVTAFRSSTSTKFNAVVNFRNAYGQLAGTEINKLPLYGLLAVAYVVAMALYSFAFW
                     KHKHELLPLQKYLLAFFVFLTAETIFVWAYYDLKNEKGDTAGIKVYMVFLSILTAGKV
                     TFSFFLLLIIALGYGIVYPKLNKTLMRRCQMYGALTYAICIGFLIQSYLTDMEAPSPL
                     ILITLIPMALALIIFYYMIIRSMTKTVIYLKEQRQIVKLNMYKKLLYIIYASFLSVLA
                     GSIVSSFIYVGMNTIDMIEKNWRSRFFVTDFWPTLVYFIVFVTIAFLWRPTDTSYMLA
                     ASQQLPTDPENVADFDLGDLQSFDDQDDASIITGERGIDEDDLNLNFTDDEEGHDNVN
                     NHSQGHGPVSPSPTK"
     gene            364776..364876
                     /locus_tag="snR69"
                     /db_xref="GeneID:9164914"
     ncRNA           364776..364876
                     /locus_tag="snR69"
                     /ncRNA_class="snoRNA"
                     /product="SNR69"
                     /note="C/D box small nucleolar RNA (snoRNA); guides
                     2'-O-methylation of large subunit (LSU) rRNA at position
                     C2948"
                     /transcript_id="NR_132201.1"
                     /db_xref="GI:831416126"
                     /db_xref="SGD:S000006460"
                     /db_xref="GeneID:9164914"
     gene            <365605..>369117
                     /gene="RGT1"
                     /locus_tag="YKL038W"
                     /db_xref="GeneID:853828"
     mRNA            <365605..>369117
                     /gene="RGT1"
                     /locus_tag="YKL038W"
                     /product="Rgt1p"
                     /transcript_id="NM_001179604.3"
                     /db_xref="GI:398364608"
                     /db_xref="GeneID:853828"
     CDS             365605..369117
                     /gene="RGT1"
                     /locus_tag="YKL038W"
                     /note="Glucose-responsive transcription factor; regulates
                     expression of several glucose transporter (HXT) genes in
                     response to glucose; binds to promoters and acts both as a
                     transcriptional activator and repressor; recruits
                     Tup1p/Cyc8p to target gene promoters; RGT1 has a paralog,
                     EDS1, that arose from the whole genome duplication"
                     /codon_start=1
                     /product="Rgt1p"
                     /protein_id="NP_012886.3"
                     /db_xref="GI:398364609"
                     /db_xref="SGD:S000001521"
                     /db_xref="GeneID:853828"
                     /translation="MNELNTVSTNSSDSTKNGGTSNSPDDMDSAAAASHAIKKRTKAS
                     RACDQCRKKKIKCDYKDEKGVCSNCQRNGDRCSFDRVPLKRGPSKGYTRSTSHPRTNE
                     IQDHNNSRSYNTFDNSNNTLNNNTGNSGDNGINSNTVPSTPSRSNSVLLPPLTQYIPQ
                     AGGIPPSFQNPAIQSTMPAGNIGQQQFWKVPYHEFQHQRKGSIDSLQSDISVRTLNPN
                     EQLSYNTVQQSPITNKHTNDSGNANGSVTGSGSASGSGGYWSFIRTSGLLAPTDDHNG
                     EQTRRSSSIPSLLRNTSNSLLLGGQPQLPPPQQQSQPQAHQQKLQQGQNLYSYSQFSQ
                     QQPYNPSISSFGQFAANGFHSRQGSVASEAMSPSAPAMFTSTSTNPVNVAQQTQRPQG
                     QQVPQFSSELDGNKRRQSAPVSVTLSTDRLNGNENNNGEINNNNGSNNSGSSKDTSQH
                     SQESVTTPAALEASSPGSTPQRSTKKRRKSYVSKKTKPKRDSSISITSKDSAHPMTTS
                     STIAYGQISDVDLIDTYYEFIHVGFPIIPLNKTTLTSDLLLVNTQPISNIHEVNSYVI
                     LWFRNSLELLVRVALKQKPGGKFFDNIVGVALSPSNDNNKAGFTTATARDDAEKTRRD
                     SHNEVQDTLEVQSVFIAALNECFQKIVDIHPKFRENNDQISPKIKVIYLSTFILLNYI
                     LAFVGYDNSFVLGMSVTIFNEFKLYKLLLFPEPDINDVKPPVDEEVSTGNGNTKTSEF
                     EIGSESAGHMNPSNSPNSMDENISHYSVLFKRLYVLLSVFDSLQSCAFGGPKLLNISI
                     QGSTERFFSNDLGSKWCLEQSQLRLKSVLQSLKLGELMSELTRNRISMNGNRKPGFDI
                     TNSSSLLSEYVETQPLSVAQLFCKLLIGKHNFINCLLSLYDSEAGVYSDLTLDLSSKI
                     ADSLCSLISIILQVLTLILRLNPTNSIDFNYRPPNPPANNPTVQEGPSAMGSSPVAGN
                     LSAAPPSEGNPDFYKKLLGLKQDTGTILSDLCRGIISPFAIAILHEVYNITELVKQMP
                     TSLISIMMTATTTQNTQDTKKSQDLVMKLSNSMNEVVQITSVLTMIKPFKIFEHELNK
                     PIMSLTGGLSSTTRNDVMWPKSGQGLRESSVMKTLLDERRTSGTQPTTAPVAAEEPRL
                     ENVALENFVSIGWKLLDDSELGWY"
     gene            <369365..>369721
                     /gene="AIM26"
                     /locus_tag="YKL037W"
                     /db_xref="GeneID:853829"
     mRNA            <369365..>369721
                     /gene="AIM26"
                     /locus_tag="YKL037W"
                     /product="Aim26p"
                     /transcript_id="NM_001179603.1"
                     /db_xref="GI:296146339"
                     /db_xref="GeneID:853829"
     CDS             369365..369721
                     /gene="AIM26"
                     /locus_tag="YKL037W"
                     /note="hypothetical protein; null mutant is viable and
                     displays elevated frequency of mitochondrial genome loss;
                     null mutation confers sensitivity to tunicamycin and DTT"
                     /codon_start=1
                     /product="Aim26p"
                     /protein_id="NP_012887.1"
                     /db_xref="GI:6322814"
                     /db_xref="SGD:S000001520"
                     /db_xref="GeneID:853829"
                     /translation="MQTMGGEHLLLSQLKGSFFLLLLAYFFRGRSPYYARCYRRLAVT
                     PGAITIAIAIATDSIPALAKSKVLVSVCSHTDPCTASCNLIPFPRPFSNSLTRFLFCL
                     GSARFCISFPCFGLSI"
     gene            <369891..>371390
                     /gene="UGP1"
                     /locus_tag="YKL035W"
                     /db_xref="GeneID:853830"
     mRNA            <369891..>371390
                     /gene="UGP1"
                     /locus_tag="YKL035W"
                     /product="UTP glucose-1-phosphate uridylyltransferase"
                     /transcript_id="NM_001179601.3"
                     /db_xref="GI:398364618"
                     /db_xref="GeneID:853830"
     CDS             369891..371390
                     /gene="UGP1"
                     /locus_tag="YKL035W"
                     /EC_number="2.7.7.9"
                     /note="UDP-glucose pyrophosphorylase (UGPase); catalyses
                     the reversible formation of UDP-Glc from glucose
                     1-phosphate and UTP, involved in a wide variety of
                     metabolic pathways, expression modulated by Pho85p through
                     Pho4p; UGP1 has a paralog, YHL012W, that arose from the
                     whole genome duplication"
                     /codon_start=1
                     /product="UTP glucose-1-phosphate uridylyltransferase"
                     /protein_id="NP_012889.3"
                     /db_xref="GI:398364619"
                     /db_xref="SGD:S000001518"
                     /db_xref="GeneID:853830"
                     /translation="MSTKKHTKTHSTYAFESNTNSVAASQMRNALNKLADSSKLDDAA
                     RAKFENELDSFFTLFRRYLVEKSSRTTLEWDKIKSPNPDEVVKYEIISQQPENVSNLS
                     KLAVLKLNGGLGTSMGCVGPKSVIEVREGNTFLDLSVRQIEYLNRQYDSDVPLLLMNS
                     FNTDKDTEHLIKKYSANRIRIRSFNQSRFPRVYKDSLLPVPTEYDSPLDAWYPPGHGD
                     LFESLHVSGELDALIAQGREILFVSNGDNLGATVDLKILNHMIETGAEYIMELTDKTR
                     ADVKGGTLISYDGQVRLLEVAQVPKEHIDEFKNIRKFTNFNTNNLWINLKAVKRLIES
                     SNLEMEIIPNQKTITRDGHEINVLQLETACGAAIRHFDGAHGVVVPRSRFLPVKTCSD
                     LLLVKSDLFRLEHGSLKLDPSRFGPNPLIKLGSHFKKVSGFNARIPHIPKIVELDHLT
                     ITGNVFLGKDVTLRGTVIIVCSDGHKIDIPNGSILENVVVTGNLQILEH"
     gene            <371829..>374105
                     /gene="TUL1"
                     /locus_tag="YKL034W"
                     /db_xref="GeneID:853832"
     mRNA            <371829..>374105
                     /gene="TUL1"
                     /locus_tag="YKL034W"
                     /product="ubiquitin-protein ligase TUL1"
                     /transcript_id="NM_001179600.1"
                     /db_xref="GI:296146341"
                     /db_xref="GeneID:853832"
     CDS             371829..374105
                     /gene="TUL1"
                     /locus_tag="YKL034W"
                     /EC_number="6.3.2.-"
                     /note="Subunit of the DSC ubiquitin ligase complex;
                     golgi-localized RING-finger ubiquitin ligase (E3) involved
                     in sorting polar transmembrane domain containing membrane
                     proteins to multivesicular bodies for delivery to the
                     vacuole; proposed involvement in the quality control of
                     misfolded TMD containing proteins; ortholog of fission
                     yeast dsc1"
                     /codon_start=1
                     /product="ubiquitin-protein ligase TUL1"
                     /protein_id="NP_012890.1"
                     /db_xref="GI:6322817"
                     /db_xref="SGD:S000001517"
                     /db_xref="GeneID:853832"
                     /translation="MEIDGNTLVFIIVILFLFFSSPGGDGVSSQYEFNQLQRLKQQFR
                     TEHNTFVNMTYTDSFRNITGLKLSYQDMLNNPLQNATYPLPGKDYDRWFPNQNYMVLP
                     NDVIEAINTEVWNTSNDDASNLFPPNITSTLLGKIDLVSNNKYEKIRMPVPRFYEPAT
                     DFSEDIPPEGETYWSEWPSYGELHNVSFQHGEIAIQISHMSNLQDNNNYLRRNFINKK
                     NDRWKLLNLQIDFSDKAEKEKHSIYSKAVYDIQRGRILSISQSSKFHSLFALPHYMSF
                     QNDYNEKIFNDVKELVDEFWNFTDYTDVMTMKDVQDAYNNANFKCEYLIFLQLEPWNQ
                     YTRDQIKLIDDELNWPLGRPANLSSLPPINVVSGLLYSPDCGVRLGLHNVKGTRYELK
                     IMSIRKHLLFGIALFAAQIYLLLTQMHHTNTPSMVNKISFYCFSMINLVDGSLATLYF
                     VAASVVPELYLPLVISAFSCFILASIFEIRYLISIYASQVNEQNVGIINLLRGNTGTY
                     DENRPRPAFIPDEGSIGGSLYGRFFFMLIIFTFLILSSTSWPRQLRMVFEYILIFILN
                     SYWIPQIFRNAVKGIPSRRERARSSIGGNRSQNKMPLLWSFVIGTTIIRSLPVVYVFT
                     YSSNVFRHHKDVHFVVFLSLWLLFQISILYSQDVLGSRWFLPKHTIPDGYSYFKPLSN
                     EYISEHGGGTAEHTVDCAICMSDVPIYIEEIPETHKVDQHSYMVTPCNHVFHTSCLEN
                     WMNYKLQCPVCRSPLPPL"
     gene            <374505..>375215
                     /locus_tag="YKL033W-A"
                     /db_xref="GeneID:853833"
     mRNA            <374505..>375215
                     /locus_tag="YKL033W-A"
                     /product="hypothetical protein"
                     /transcript_id="NM_001184335.3"
                     /db_xref="GI:398364624"
                     /db_xref="GeneID:853833"
     CDS             374505..375215
                     /locus_tag="YKL033W-A"
                     /EC_number="3.-.-.-"
                     /note="hypothetical protein; similar to uncharacterized
                     proteins from other fungi"
                     /codon_start=1
                     /product="hypothetical protein"
                     /protein_id="NP_012891.4"
                     /db_xref="GI:398364625"
                     /db_xref="SGD:S000007242"
                     /db_xref="GeneID:853833"
                     /translation="MTHPVAVKACLFDMDGLLINTEDIYTETLNETLAEFGKGPLTWD
                     VKIKLQGLPGPEAGKRVIEHYKLPITLDEYDERNVALQSLKWGTCEFLPGALNLLKYL
                     KLKNIPIALCTSSNKTKFRGKTSHLEEGFDLFDTIVTGDDPRIAKGRGKPFPDIWQLG
                     LKELNEKFHTDIKPDECIVFEDGIPGVKSAKAFGAHVIWVPHPEAHAVLGDTEALLAG
                     KGELLSSLEKLEMSKYGL"
     gene            <375456..>378572
                     /gene="TTI1"
                     /locus_tag="YKL033W"
                     /db_xref="GeneID:853834"
     mRNA            <375456..>378572
                     /gene="TTI1"
                     /locus_tag="YKL033W"
                     /product="Tti1p"
                     /transcript_id="NM_001179599.1"
                     /db_xref="GI:296146343"
                     /db_xref="GeneID:853834"
     CDS             375456..378572
                     /gene="TTI1"
                     /locus_tag="YKL033W"
                     /note="Subunit of the ASTRA complex, involved in chromatin
                     remodeling; telomere length regulator involved in the
                     stability or biogenesis of PIKKs such as TORC1; similar to
                     S. pombe Tti1p; detected in highly purified mitochondria
                     in high-throughput studies"
                     /codon_start=1
                     /product="Tti1p"
                     /protein_id="NP_012892.1"
                     /db_xref="GI:6322819"
                     /db_xref="SGD:S000001516"
                     /db_xref="GeneID:853834"
                     /translation="MNSDTNAFKDIRISCVELSRIAFLPTESFDPNSLTLLACLKKVE
                     EKLSAYEDDSLSPKFADYVFVPIASLLKQPALGESQTEYVLLIIFHLLRTCWSSNGKF
                     SEQLGQQLFPLITFLVSSDKDNQKLITRSDEFKYAGCLVLHQFFKSVRSQRYHKEFFS
                     NSKPNLLPALGHSVTILLKILEQSPQNNELQFKALASLEVLFQDIISDGEMLSFILPG
                     NVSVFAKILTKPGRQIHYKVCVRTLEVLAKLLVLVYDDFSLDIKVNKLTDIRELSDTK
                     LKHEINQSFMFNGPIVLLRTDGKTHRDTSWLTATSGQINIALEAFIPKLLKRNNESID
                     EALATFVSILLTRCENSLNNCEKVLVSTLVHLERDPMSKLPSHLVKLKEVVNEDLHKL
                     SDIIRFENADRLSSLSFAITILEKNNERDTMINEVVRCLFESLNESIEPPSLINHKER
                     IIEQSSQLTTTVNFENLESTNALIALPRLSEDMSLKLKKFTYHMGSLLLERHILNDVV
                     TELISEQVDSPRTQKIVALWLSTNFIKAMEKQPKEEEVYLQFESDANYSSSMVEEVCL
                     IVLEFCNELSQDISMEIEGKGIKKSDEFAVCTVLFSIETICAVMREEFQPELIDYIYT
                     VVDALASPSEAIRYVSQSCALRIADTLYHGSIPNMILSNVDYLVESISSRLNSGMTER
                     VSQILMVICQLAGYETIENFKDVIETIFKLLDYYHGYSDLCLQFFQLFKIIILEMKKK
                     YINDDEMILKIANQHISQSTFSPWGMTDFQQVLNILDKETQVKDDITDENDVDFLKDD
                     NEPSNFQEYFDSKLREPDSDDDEEEREEEVEGSSKEYTDQWTSPIPSDSYKILLQILG
                     YGERLLTHPSKRLRVQILIVMRLIFPLLSTQHNLLIREVASTWDSIIQCVLCSDYSIV
                     QPACSCVEQMIKYSGDFVAKRFIELWQKLCQDSFILKELRIDPTVHNHEKKSISKHVK
                     FPPVTENALVSMVHMVLEGVKITEYLISEAVLEQIIYCCIQVVPVEKISSMSLIVGDI
                     VWKIRNIN"
     gene            379680..379753
                     /locus_tag="tV(AAC)K2"
                     /db_xref="GeneID:853835"
     tRNA            379680..379753
                     /locus_tag="tV(AAC)K2"
                     /product="tRNA-Val"
                     /note="Valine tRNA (tRNA-Val), predicted by tRNAscan-SE
                     analysis"
                     /db_xref="SGD:S000006761"
                     /db_xref="GeneID:853835"
     gene            complement(<380065..>381858)
                     /gene="IXR1"
                     /locus_tag="YKL032C"
                     /gene_synonym="ORD1"
                     /db_xref="GeneID:853836"
     mRNA            complement(<380065..>381858)
                     /gene="IXR1"
                     /locus_tag="YKL032C"
                     /gene_synonym="ORD1"
                     /product="Ixr1p"
                     /transcript_id="NM_001179598.3"
                     /db_xref="GI:398364634"
                     /db_xref="GeneID:853836"
     CDS             complement(380065..381858)
                     /gene="IXR1"
                     /locus_tag="YKL032C"
                     /gene_synonym="ORD1"
                     /note="Transcriptional repressor that regulates hypoxic
                     genes during normoxia; involved in the aerobic repression
                     of genes such as COX5b, TIR1, and HEM13; binds DNA
                     intrastrand cross-links formed by cisplatin; HMG (high
                     mobility group box) domain containing protein which binds
                     and bends cisplatin-modified DNA, blocking excision
                     repair; IXR1 has a paralog, ABF2, that arose from the
                     whole genome duplication"
                     /codon_start=1
                     /product="Ixr1p"
                     /protein_id="NP_012893.3"
                     /db_xref="GI:398364635"
                     /db_xref="SGD:S000001515"
                     /db_xref="GeneID:853836"
                     /translation="MNTGISPKQDDASNSNLLNIGQDHSLQYQGLEHNDSQYRDASHQ
                     TPHQYLNQFQAQPQQQQQQQQQQQQQQQQAPYQGHFQQSPQQQQQNVYYPLPPQSLTQ
                     PTSQSQQQQQQQQQQQYANSNSNSNNNVNVNALPQDFGYMQQTGSGQNYPTINQQQFS
                     EFYNSFLSHLTQKQTNPSVTGTGASSNNNSNNNNVSSGNNSTSSNPAQLAASQLNPAT
                     AAAAAANNAAGPASYLSQLPQVQRYYPNNMNALSSLLDPSSAGNAAGNANTATHPGLL
                     PPNLQPQLTHHQQQMQQQLQLQQQQQLQQQQQLQQQHQLQQQQQLQQQHHHLQQQQQQ
                     QQHPVVKKLSSTQSRIERRKQLKKQGPKRPSSAYFLFSMSIRNELLQQFPEAKVPELS
                     KLASARWKELTDDQKKPFYEEFRTNWEKYRVVRDAYEKTLPPKRPSGPFIQFTQEIRP
                     TVVKENPDKGLIEITKIIGERWRELDPAKKAEYTETYKKRLKEWESCYPDENDPNGNP
                     TGHSHKAMNMNLNMDTKIMENQDSIEHITANAIDSVTGSNSNSTNPNTPVSPPISLQQ
                     QPLQQQQQQQQQQQHMLLADPTTNGSIIKNE"
     gene            complement(<382716..>384725)
                     /gene="MAE1"
                     /locus_tag="YKL029C"
                     /db_xref="GeneID:853839"
     mRNA            complement(<382716..>384725)
                     /gene="MAE1"
                     /locus_tag="YKL029C"
                     /product="malate dehydrogenase
                     (oxaloacetate-decarboxylating)"
                     /transcript_id="NM_001179595.1"
                     /db_xref="GI:296146345"
                     /db_xref="GeneID:853839"
     CDS             complement(382716..384725)
                     /gene="MAE1"
                     /locus_tag="YKL029C"
                     /EC_number="1.1.1.38"
                     /note="Mitochondrial malic enzyme; catalyzes the oxidative
                     decarboxylation of malate to pyruvate, which is a key
                     intermediate in sugar metabolism and a precursor for
                     synthesis of several amino acids"
                     /codon_start=1
                     /product="malate dehydrogenase
                     (oxaloacetate-decarboxylating)"
                     /protein_id="NP_012896.1"
                     /db_xref="GI:6322823"
                     /db_xref="SGD:S000001512"
                     /db_xref="GeneID:853839"
                     /translation="MLRTRLSVSVAARSQLTRSLTASRTAPLRRWPIQQSRLYSSNTR
                     SHKATTTRENTFQKPYSDEEVTKTPVGSRARKIFEAPHPHATRLTVEGAIECPLESFQ
                     LLNSPLFNKGSAFTQEEREAFNLEALLPPQVNTLDEQLERSYKQLCYLKTPLAKNDFM
                     TSLRVQNKVLYFALIRRHIKELVPIIYTPTEGDAIAAYSHRFRKPEGVFLDITEPDSI
                     ECRLATYGGDKDVDYIVVSDSEGILGIGDQGIGGVRIAISKLALMTLCGGIHPGRVLP
                     VCLDVGTNNKKLARDELYMGNKFSRIRGKQYDDFLEKFIKAVKKVYPSAVLHFEDFGV
                     KNARRLLEKYRYELPSFNDDIQGTGAVVMASLIAALKHTNRDLKDTRVLIYGAGSAGL
                     GIADQIVNHMVTHGVDKEEARKKIFLMDRRGLILQSYEANSTPAQHVYAKSDAEWAGI
                     NTRSLHDVVENVKPTCLVGCSTQAGAFTQDVVEEMHKHNPRPIIFPLSNPTRLHEAVP
                     ADLMKWTNNNALVATGSPFPPVDGYRISENNNCYSFPGIGLGAVLSRATTITDKMISA
                     AVDQLAELSPLREGDSRPGLLPGLDTITNTSARLATAVILQALEEGTARIEQEQVPGG
                     APGETVKVPRDFDECLQWVKAQMWEPVYRPMIKVQHDPSVHTNQL"
     gene            <385758..>387206
                     /gene="TFA1"
                     /locus_tag="YKL028W"
                     /db_xref="GeneID:853840"
     mRNA            <385758..>387206
                     /gene="TFA1"
                     /locus_tag="YKL028W"
                     /product="Tfa1p"
                     /transcript_id="NM_001179594.3"
                     /db_xref="GI:398364644"
                     /db_xref="GeneID:853840"
     CDS             385758..387206
                     /gene="TFA1"
                     /locus_tag="YKL028W"
                     /note="TFIIE large subunit; involved in recruitment of RNA
                     polymerase II to the promoter, activation of TFIIH, and
                     promoter opening"
                     /codon_start=1
                     /product="Tfa1p"
                     /protein_id="NP_012897.3"
                     /db_xref="GI:398364645"
                     /db_xref="SGD:S000001511"
                     /db_xref="GeneID:853840"
                     /translation="MDRPIDDIVKNLLKFVVRGFYGGSFVLVLDAILFHSVLAEDDLK
                     QLLSINKTELGPLIARLRSDRLISIHKQREYPPNSKSVERVYYYVKYPHAIDAIKWKV
                     HQVVQRLKDDLDKNSEPNGYMCPICLTKYTQLEAVQLLNFDRTEFLCSLCDEPLVEDD
                     SGKKNKEKQDKLNRLMDQIQPIIDSLKKIDDSRIEENTFEIALARLIPPQNQSHAAYT
                     YNPKKGSTMFRPGDSAPLPNLMGTALGNDSSRRAGANSQATLHINITTASDEVAQREL
                     QERQAEEKRKQNAVPEWHKQSTIGKTALGRLDNEEEFDPVVTASAMDSINPDNEPAQE
                     TSYQNNRTLTEQEMEERENEKTLNDYYAALAKKQAKLNKEEEEEEEEEEDEEEEEEEE
                     MEDVMDDNDETARENALEDEFEDVTDTAGTAKTESNTSNDVKQESINDKTEDAVNATA
                     TASGPSANAKPNDGDDDDDDDDDEMDIEFEDV"
     gene            <387562..>388905
                     /gene="TCD2"
                     /locus_tag="YKL027W"
                     /db_xref="GeneID:853841"
     mRNA            <387562..>388905
                     /gene="TCD2"
                     /locus_tag="YKL027W"
                     /product="Tcd2p"
                     /transcript_id="NM_001179593.1"
                     /db_xref="GI:296146347"
                     /db_xref="GeneID:853841"
     CDS             387562..388905
                     /gene="TCD2"
                     /locus_tag="YKL027W"
                     /EC_number="6.1.-.-"
                     /note="tRNA threonylcarbamoyladenosine dehydratase;
                     required for the ct6A tRNA base modification, where an
                     adenosine at position 37 is modified to form a cyclized
                     active ester with an oxazolone ring; localized to the
                     mitochondrial outer membrane; TCD2 has a paralog, TCD1,
                     that arose from the whole genome duplication"
                     /codon_start=1
                     /product="Tcd2p"
                     /protein_id="NP_012898.1"
                     /db_xref="GI:6322825"
                     /db_xref="SGD:S000001510"
                     /db_xref="GeneID:853841"
                     /translation="MVEKDTWKLITATALFTVAVTTITDYAWTSWQAQKQVIAQQKNK
                     NKGGQTKSDTDKYHQYDEQFIRQSLKNNVEFLGEDTIEKLSNQYVVVVGAGGVGSWVV
                     NSLVRSGCRKIRVVDFDQVSLSSLNRHSCAILNDVGTPKVECLRRHMREIAPWCEIDP
                     INELWTLQNGERLTLGNGTPDFIVDCIDNIDTKVDLLEFAYNHGIKVISSMGASAKSD
                     PTKLNVGDLATTEEDPLARVVRRKLKKRGILSGIPVVFSAEKPDPKKAKLLPLPDEEY
                     ERGKVDELSALKDFRVRILPVLGTMPSLFGLTITTWILSNISDKPLEPVEGKNRIKVY
                     DGIYQSLAGQMSRVGIPSQRIPLALKDVSYLVEEVFKGKSPISGISTRLTLTKWDPSK
                     PISLQNVVVLTKNEQKVHEDRVLKGKESLQDVYDAKVLKLVSQRFREEAYYSQFR"
     rep_origin      388970..389264
                     /note="ARS1112;
                     Autonomously Replicating Sequence"
                     /db_xref="SGD:S000118404"
     gene            complement(<389380..>389883)
                     /gene="GPX1"
                     /locus_tag="YKL026C"
                     /db_xref="GeneID:853842"
     mRNA            complement(<389380..>389883)
                     /gene="GPX1"
                     /locus_tag="YKL026C"
                     /product="glutathione peroxidase GPX1"
                     /transcript_id="NM_001179592.3"
                     /db_xref="GI:398364658"
                     /db_xref="GeneID:853842"
     CDS             complement(389380..389883)
                     /gene="GPX1"
                     /locus_tag="YKL026C"
                     /EC_number="1.11.1.9"
                     /note="Phospholipid hydroperoxide glutathione peroxidase;
                     induced by glucose starvation that protects cells from
                     phospholipid hydroperoxides and nonphospholipid peroxides
                     during oxidative stress; GPX1 has a paralog, HYR1, that
                     arose from the whole genome duplication"
                     /codon_start=1
                     /product="glutathione peroxidase GPX1"
                     /protein_id="NP_012899.3"
                     /db_xref="GI:398364659"
                     /db_xref="SGD:S000001509"
                     /db_xref="GeneID:853842"
                     /translation="MQEFYSFSPIDENGNPFPFNSLRNKVVLIVNVASHCAFTPQYKE
                     LEYLYEKYKSHGLVIVAFPCGQFGNQEFEKDKEINKFCQDKYGVTFPILHKIRCNGQK
                     QDPVYKFLKNSVSGKSGIKMIKWNFEKFVVDRNGKVVKRFSCMTRPLELCPIIEELLN
                     QPPEEQI"
     gene            complement(<390240..>392279)
                     /gene="PAN3"
                     /locus_tag="YKL025C"
                     /gene_synonym="ECM35"
                     /db_xref="GeneID:853843"
     mRNA            complement(<390240..>392279)
                     /gene="PAN3"
                     /locus_tag="YKL025C"
                     /gene_synonym="ECM35"
                     /product="Pan3p"
                     /transcript_id="NM_001179591.1"
                     /db_xref="GI:296146349"
                     /db_xref="GeneID:853843"
     CDS             complement(390240..392279)
                     /gene="PAN3"
                     /locus_tag="YKL025C"
                     /gene_synonym="ECM35"
                     /note="Essential subunit of the Pan2p-Pan3p
                     poly(A)-ribonuclease complex; poly (A) mRNA binding
                     subunit which recruits mRNA to the complex; the
                     Pan2p-Pan3p complex controls poly(A) tail length and
                     regulates the stoichiometry and activity of
                     postreplication repair complexes"
                     /codon_start=1
                     /product="Pan3p"
                     /protein_id="NP_012900.1"
                     /db_xref="GI:6322827"
                     /db_xref="SGD:S000001508"
                     /db_xref="GeneID:853843"
                     /translation="MDKINPDWAKDIPCRNITIYGYCKKEKEGCPFKHSDNTTATTIN
                     DVPPPIDVGEATTPTMTSVPKFNAKVSASFTPMTVGSDSLTTVTNTTSAATNATGNIA
                     MAATSATASTVNPMINPIVNSSLVNNNNNNSNISISIPTTASSSNYDPFNAPIFTPSS
                     TSSIHTNANAHSFPFPSIANSGGININATDDNSNNMSMANNVPPPMQPPPIESSNLKY
                     PRIYPPPHSLLQYHLYAPEQPSSLKSLLKPNERSADQLFIPNNIREDLTKKNLSILQV
                     FPSSGKVIPSIVQDYFNLVPLNFNNNDFLNKTTLFKVFSNYDGKAYVLKRLPNIDKSM
                     NPNKISKIYQIWSKINCTNLIKFRDIFQTTKFGDLSICLVFDYYPNSLSLYDYHFVNF
                     PKFPITNNYLWIYLVQLTNVINSIHSQNLSIGNTLNWRKVLITGDPGRIKLSHCNFMD
                     LLFNDDTDTVVSSGGSTIEGQQQLDYKYLGELLFNLSINIENSNNNTAPKEYRLEEIT
                     PQSIDDMRQIDDKFKDVLKYLISDNGDSKKSIHDLTSHFYDKMFMVLESSQTYTEYME
                     SVLSRELENGRLFRLVNKLNCIFGRIESRIDINWSESGTKFPIILFYDYVFHQVDSNG
                     KPIMDLTHVLRCLNKLDAGIQEKLMLVTPDELNCIIISYKELKDLIESTFRSITQ"
     gene            complement(<392526..>393140)
                     /gene="URA6"
                     /locus_tag="YKL024C"
                     /gene_synonym="SOC8"
                     /db_xref="GeneID:853844"
     mRNA            complement(<392526..>393140)
                     /gene="URA6"
                     /locus_tag="YKL024C"
                     /gene_synonym="SOC8"
                     /product="bifunctional uridylate/adenylate kinase"
                     /transcript_id="NM_001179590.3"
                     /db_xref="GI:398364670"
                     /db_xref="GeneID:853844"
     CDS             complement(392526..393140)
                     /gene="URA6"
                     /locus_tag="YKL024C"
                     /gene_synonym="SOC8"
                     /EC_number="2.7.4.14"
                     /note="Uridylate kinase; catalyzes the seventh enzymatic
                     step in the de novo biosynthesis of pyrimidines,
                     converting uridine monophosphate (UMP) into
                     uridine-5'-diphosphate (UDP)"
                     /codon_start=1
                     /product="bifunctional uridylate/adenylate kinase"
                     /protein_id="NP_012901.3"
                     /db_xref="GI:398364671"
                     /db_xref="SGD:S000001507"
                     /db_xref="GeneID:853844"
                     /translation="MTAATTSQPAFSPDQVSVIFVLGGPGAGKGTQCEKLVKDYSFVH
                     LSAGDLLRAEQGRAGSQYGELIKNCIKEGQIVPQEITLALLRNAISDNVKANKHKFLI
                     DGFPRKMDQAISFERDIVESKFILFFDCPEDIMLERLLERGKTSGRSDDNIESIKKRF
                     NTFKETSMPVIEYFETKSKVVRVRCDRSVEDVYKDVQDAIRDSL"
     gene            complement(<393146..>393373)
                     /locus_tag="YKL023C-A"
                     /db_xref="GeneID:3799976"
     mRNA            complement(<393146..>393373)
                     /locus_tag="YKL023C-A"
                     /product="hypothetical protein"
                     /transcript_id="NM_001184683.1"
                     /db_xref="GI:296146351"
                     /db_xref="GeneID:3799976"
     CDS             complement(393146..393373)
                     /locus_tag="YKL023C-A"
                     /codon_start=1
                     /product="hypothetical protein"
                     /protein_id="NP_001032581.1"
                     /db_xref="GI:82795258"
                     /db_xref="SGD:S000113559"
                     /db_xref="GeneID:3799976"
                     /translation="MNPRYRFILRFYSSKKPTFHNTAPSKTNVNVPRANKSQSKGKHK
                     GKLLVLVGTLALVTSVISVNYQKNEPVEFLE"
     gene            <393721..>394554
                     /locus_tag="YKL023W"
                     /db_xref="GeneID:853845"
     mRNA            <393721..>394554
                     /locus_tag="YKL023W"
                     /product="hypothetical protein"
                     /transcript_id="NM_001179589.4"
                     /db_xref="GI:398364678"
                     /db_xref="GeneID:853845"
     CDS             393721..394554
                     /locus_tag="YKL023W"
                     /note="hypothetical protein; predicted by computational
                     methods to be involved in mRNA degradation; green
                     fluorescent protein (GFP)-fusion protein localizes to the
                     cytoplasm"
                     /codon_start=1
                     /product="hypothetical protein"
                     /protein_id="NP_012902.4"
                     /db_xref="GI:398364679"
                     /db_xref="SGD:S000001506"
                     /db_xref="GeneID:853845"
                     /translation="MNKEELLGFLLDDSIDSQKRCVTDQQAYSNWLKNDNDERTAHEE
                     SSSQSTIAALNKKKQTEAAQEDIEELLNGLEGIIGGADPRNLKSKSKRKTKKGGSKPR
                     EENVNTEKHIVMLEVEDFSDMSTHEDVNGASPSPNLDRSKKNEKRRKNAKELSYDELK
                     DKLEVTTRKSRLECKDLKKKVHGLERRNLELEQRLEELKIENQTLIEINNKLLKNTNE
                     DEINKSQRNKEKDRKRRERRTARRKDERKQEKKQEKKQDNKTSQSFPSSTDMNGQPIE
                     F"
     gene            complement(<394726..>397248)
                     /gene="CDC16"
                     /locus_tag="YKL022C"
                     /db_xref="GeneID:853846"
     mRNA            complement(<394726..>397248)
                     /gene="CDC16"
                     /locus_tag="YKL022C"
                     /product="anaphase promoting complex subunit CDC16"
                     /transcript_id="NM_001179588.1"
                     /db_xref="GI:296146353"
                     /db_xref="GeneID:853846"
     CDS             complement(394726..397248)
                     /gene="CDC16"
                     /locus_tag="YKL022C"
                     /note="Subunit of the anaphase-promoting complex/cyclosome
                     (APC/C); which is a ubiquitin-protein ligase required for
                     degradation of anaphase inhibitors, including mitotic
                     cyclins, during the metaphase/anaphase transition;
                     required for sporulation; relocalizes to the cytosol in
                     response to hypoxia"
                     /codon_start=1
                     /product="anaphase promoting complex subunit CDC16"
                     /protein_id="NP_012903.1"
                     /db_xref="GI:6322830"
                     /db_xref="SGD:S000001505"
                     /db_xref="GeneID:853846"
                     /translation="MKFCLYCCHCYIVICGKATHYYKSSKATSNLKSSNRVLMRNPMS
                     PSEQHSQHNSTLAASPFVSNVSAARTQQSLPTDAQNDRLQQPWNRTNTATSPYQSLAN
                     SPLIQKLQANIMTPHQPSANSNSNSNSITGNVVNDNNLLASMSKNSMFGSTIPSTLRK
                     VSLQREYKDSVDGVVRDEDNDEDVHNNGDAAANANNDRESKLGHNGPLTTTTLTTTTT
                     ATQLDVSELSAIERLRLWRFDALMQHMYRTAEYIADKVYNISNDPDDAFWLGQVYYNN
                     NQYVRAVELITRNNLDGVNILCRYLLGLSFVKLQRFDDALDVIGEYNPFSEDPSTTAA
                     NTMSNNGNNSNTSQPVTDGGIKMESSLCFLRGKIYFAQNNFNKARDAFREAILVDIKN
                     FEAFEMLLSKNLLTPQEEWDLFDSLDFKEFGEDKEIMKNLYKINLSKYINTEDITKSN
                     EILAKDYKLADNVDVVRSKVDICYTQCKFNECLELCETVLENDEFNTNILPAYIGCLY
                     ELSNKNKLFLLSHRLAETFPKSAITWFSVATYYMSLDRISEAQKYYSKSSILDPSFAA
                     AWLGFAHTYALEGEQDQALTAYSTASRFFPGMHLPKLFLGMQFMAMNSLNLAESYFVL
                     AYDICPNDPLVLNEMGVMYFKKNEFVKAKKYLKKALEVVKDLDPSSRTTISIQLNLGH
                     TYRKLNENEIAIKCFRCVLEKNDKNSEIHCSLGYLYLKTKKLQKAIDHLHKSLYLKPN
                     NSSATALLKNALELNVTLSLDASHPLIDKSNLMSQASKDKASLNKKRSSLTYDPVNMA
                     KRLRTQKEIFDQNNKALRKGGHDSKTGSNNADDDFDADMELE"
     gene            complement(<397344..>398750)
                     /gene="MAK11"
                     /locus_tag="YKL021C"
                     /db_xref="GeneID:853847"
     mRNA            complement(<397344..>398750)
                     /gene="MAK11"
                     /locus_tag="YKL021C"
                     /product="Mak11p"
                     /transcript_id="NM_001179587.3"
                     /db_xref="GI:398364694"
                     /db_xref="GeneID:853847"
     CDS             complement(397344..398750)
                     /gene="MAK11"
                     /locus_tag="YKL021C"
                     /note="Protein involved in an early step of 60S ribosomal
                     subunit biogenesis; essential for cell growth and
                     replication of killer M1 dsRNA virus; contains four
                     beta-transducin repeats"
                     /codon_start=1
                     /product="Mak11p"
                     /protein_id="NP_012904.3"
                     /db_xref="GI:398364695"
                     /db_xref="SGD:S000001504"
                     /db_xref="GeneID:853847"
                     /translation="MLLNTTYTVFIFFLLRIIKFKIKAENFLEHEKLKTHGTSSRKDP
                     KGQVKNSCRKMSAIGDKNQFRIIVGSYEHNILCLSLDIPNQKENDAAKTPHFMPIFHF
                     QAHSLSIKCLAVSRRYLVSGSNDEHIRIYDLQKRKELGTLLSHQGSITALQFSHPASS
                     SEDAAVSKGSKNSKWLLSASEDHKIMVWRVKDWETVGTLKGHTARVNDVDIHPTNRIA
                     ISVSDDHSIRLWNLMTLRNAAVLKLRKYNTNGTCVRWLGAKGDYFAVGLRDRVLIYET
                     GSAKVFKEIVFQRKTLMHIETHILPFDNKEYLSVGISDGNVHFYPCEELFEKVEENEK
                     QEDDDDKEDISPAFSLLGHTNRIKDFKFYTNEFGTYLVTIGSDGKIVVWDMSTKEQVA
                     VYDCGERLNCLTLCDESIEKYNTMKKRDAETADIGDQSEVESDTEELKKIMFGEKKKL
                     NKKKRKQLKKSKVSVELE"
     gene            complement(<398832..>402080)
                     /gene="SPT23"
                     /locus_tag="YKL020C"
                     /db_xref="GeneID:853848"
     mRNA            complement(<398832..>402080)
                     /gene="SPT23"
                     /locus_tag="YKL020C"
                     /product="Spt23p"
                     /transcript_id="NM_001179586.1"
                     /db_xref="GI:296146355"
                     /db_xref="GeneID:853848"
     CDS             complement(398832..402080)
                     /gene="SPT23"
                     /locus_tag="YKL020C"
                     /note="ER membrane protein involved in regulation of OLE1
                     transcription; inactive ER form dimerizes and one subunit
                     is then activated by ubiquitin/proteasome-dependent
                     processing followed by nuclear targeting; SPT23 has a
                     paralog, MGA2, that arose from the whole genome
                     duplication"
                     /codon_start=1
                     /product="Spt23p"
                     /protein_id="NP_012905.1"
                     /db_xref="GI:6322832"
                     /db_xref="SGD:S000001503"
                     /db_xref="GeneID:853848"
                     /translation="MMSGTGNVSSMLHSYSANIQHNDGSPDLDLLESELLDIALLNSG
                     SSLQDPGLLSLNQEKMITAGTTTPGKEDEGELRDDIASLQGLLDRHVQFGRKLPLRTP
                     YANPLDFININPQSLPLSLEIIGLPKVSRVETQMKLSFRIRNAHARKNFFIHLPSDCI
                     AKDKFFTSSDDPTNLTIPNRDINERTLFLDAFLLCASNNNSNNFKQTYVCNRCINREK
                     RRASRRKSGLNDNSIWQNNENKRAIIFNSKQLFIISNNGLSGNSNCINFDLPTRIVCY
                     CRHHKATNGFVVLFLLRDHNGDILAKTITDPIMIMDKKNASNTTTPTSTSNAQVSPMT
                     NDTRSFSSPQSDLNFPSEFPLPSNSKNFVISTNCMLDSNCNNNNNDNDNKNNIKTNTA
                     MMNNNRHFPSPNSSSEDSNHSFSDIHFSNNNDNNLHRSLDSWSSTGFNSSSNPALTTL
                     TSDFSAASARHTGKRQRSVNEPFMSTPNTFSRLPQKFIDSSKDISNHNSVPVALNNKP
                     SIQRVIPAQGSINGGIEVTLLGSKFKQGLIIKFGENIALSSQCWNESTMVTYLPPSSK
                     PGPVLVTIVDPSETSMRNNSNSSVSTSNSTNDILHLNKYTGEKAIFTYVDDTDRQLIE
                     LALQIVGLKMNGKLEDARNIAKRIVGSDSSPSNNNAGLHSQNSSLNSYTNMMRNINDE
                     QLITEVIKSFKRNNNLSTVNLSMCDVRGRTLLHLAAFNNWYSLVSLLIKYGSHLNDQD
                     LFGFTPLHMACINGDLRIIRLLLECNVNIMKKTRNGFIAKQFFLMNYTVNKTRYSNYE
                     TSLFDDILTRLTKNTTGSSDTQPFERNVSQSSFNSSLFDDDDADHDYVQERKYLLADS
                     AALAPEQSNCNDNTSFSILDSDSGYDISDCESSSDEIALEFFNTHKIKDFSSKPNEIP
                     KTTKTSIEPDGSLWNRMLTRLNDELPKYEDLFPKKPKNWELGSKSVEIGPDNSAQMTV
                     DDSQTSSEDDELEALQVGFNTIFSKKQNFQNDKMLLFFWIPLTLVLLLCFTLSNLGKD
                     DDMFHNLSKIVQEYLRIGLAKVLLGNERMKTSFKMQLSKFQNNNILNDMRVN"
     gene            <402568..>403518
                     /gene="RAM2"
                     /locus_tag="YKL019W"
                     /db_xref="GeneID:853849"
     mRNA            <402568..>403518
                     /gene="RAM2"
                     /locus_tag="YKL019W"
                     /product="bifunctional protein farnesyltransferase/protein
                     geranylgeranyltransferase"
                     /transcript_id="NM_001179585.3"
                     /db_xref="GI:398364710"
                     /db_xref="GeneID:853849"
     CDS             402568..403518
                     /gene="RAM2"
                     /locus_tag="YKL019W"
                     /EC_number="2.5.1.59"
                     /EC_number="2.5.1.58"
                     /note="Alpha subunit of farnesyltransferase and
                     geranylgeranyltransferase-I; farnesyltransferase
                     (RAM2-RAM1 heterodimer) catalyzes the addition of
                     15-carbon isoprenoid farnesyl to substrate proteins
                     containing a CAAX consensus motif; type I
                     geranylgeranyltransferase (RAM2-CDC43 heterodimer)
                     catalyzes the addition of the 20-carbon isoprenoid
                     geranylgeranyl to substrate proteins containing a CaaL
                     consensus motif; required for membrane localization of Ras
                     proteins and a-factor"
                     /codon_start=1
                     /product="bifunctional protein farnesyltransferase/protein
                     geranylgeranyltransferase"
                     /protein_id="NP_012906.3"
                     /db_xref="GI:398364711"
                     /db_xref="SGD:S000001502"
                     /db_xref="GeneID:853849"
                     /translation="MEEYDYSDVKPLPIETDLQDELCRIMYTEDYKRLMGLARALISL
                     NELSPRALQLTAEIIDVAPAFYTIWNYRFNIVRHMMSESEDTVLYLNKELDWLDEVTL
                     NNPKNYQIWSYRQSLLKLHPSPSFKRELPILKLMIDDDSKNYHVWSYRKWCCLFFSDF
                     QHELAYASDLIETDIYNNSAWTHRMFYWVNAKDVISKVELADELQFIMDKIQLVPQNI
                     SPWTYLRGFQELFHDRLQWDSKVVDFATTFIGDVLSLPIGSPEDLPEIESSYALEFLA
                     YHWGADPCTRDNAVKAYSLLAIKYDPIRKNLWHHKINNLN"
     gene            complement(<403580..>403879)
                     /locus_tag="YKL018C-A"
                     /db_xref="GeneID:853850"
     mRNA            complement(<403580..>403879)
                     /locus_tag="YKL018C-A"
                     /product="hypothetical protein"
                     /transcript_id="NM_001184481.1"
                     /db_xref="GI:296146357"
                     /db_xref="GeneID:853850"
     CDS             complement(403580..403879)
                     /locus_tag="YKL018C-A"
                     /note="hypothetical protein; identified by homology; green
                     fluorescent protein (GFP)-fusion protein localizes to the
                     cytoplasm"
                     /codon_start=1
                     /product="hypothetical protein"
                     /protein_id="NP_076899.1"
                     /db_xref="GI:13129177"
                     /db_xref="SGD:S000007615"
                     /db_xref="GeneID:853850"
                     /translation="MLGMIRWVVEGTLVAMLLSAIRRETGMIFFYNQYQLGGWIHRYL
                     SWGEMCYTRTLKMVKRSKFFRKQLNEDGFGRINDSGPKRRGRDQSQYSSRFVELD"
     gene            <404102..>405091
                     /gene="SWD2"
                     /locus_tag="YKL018W"
                     /gene_synonym="CPS35; SAF37"
                     /db_xref="GeneID:853851"
     mRNA            <404102..>405091
                     /gene="SWD2"
                     /locus_tag="YKL018W"
                     /gene_synonym="CPS35; SAF37"
                     /product="Swd2p"
                     /transcript_id="NM_001179584.3"
                     /db_xref="GI:398364726"
                     /db_xref="GeneID:853851"
     CDS             404102..405091
                     /gene="SWD2"
                     /locus_tag="YKL018W"
                     /gene_synonym="CPS35; SAF37"
                     /note="Subunit of the COMPASS (Set1C) histone H3K4
                     methyltransferase complex; required for Set1C stability
                     and optimal activity; COMPASS methylates histone H3 on lys
                     4 and is involved in telomeric silencing; subunit of CPF
                     (cleavage and polyadenylation factor), a complex involved
                     in RNAP II transcription termination"
                     /codon_start=1
                     /product="Swd2p"
                     /protein_id="NP_012907.3"
                     /db_xref="GI:398364727"
                     /db_xref="SGD:S000001501"
                     /db_xref="GeneID:853851"
                     /translation="MTTVSINKPNLLKFKHVKSFQPQEKDCGPVTSLNFDDNGQFLLT
                     SSSNDTMQLYSATNCKFLDTIASKKYGCHSAIFTHAQNECIYSSTMKNFDIKYLNLET
                     NQYLRYFSGHGALVNDLKMNPVNDTFLSSSYDESVRLWDLKISKPQVIIPSLVPNCIA
                     YDPSGLVFALGNPENFEIGLYNLKKIQEGPFLIIKINDATFSQWNKLEFSNNGKYLLV
                     GSSIGKHLIFDAFTGQQLFELIGTRAFPMREFLDSGSACFTPDGEFVLGTDYDGRIAI
                     WNHSDSISNKVLRPQGFIPCVSHETCPRSIAFNPKYSMFVTADETVDFYVYDE"
     gene            complement(<405190..>407241)
                     /gene="HCS1"
                     /locus_tag="YKL017C"
                     /gene_synonym="DIP1"
                     /db_xref="GeneID:853852"
     mRNA            complement(<405190..>407241)
                     /gene="HCS1"
                     /locus_tag="YKL017C"
                     /gene_synonym="DIP1"
                     /product="ATP-dependent 5'-3' DNA helicase HCS1"
                     /transcript_id="NM_001179583.1"
                     /db_xref="GI:296146359"
                     /db_xref="GeneID:853852"
     CDS             complement(405190..407241)
                     /gene="HCS1"
                     /locus_tag="YKL017C"
                     /gene_synonym="DIP1"
                     /EC_number="3.6.4.12"
                     /note="Hexameric DNA polymerase alpha-associated DNA
                     helicase A; involved in lagging strand DNA synthesis;
                     contains single-stranded DNA stimulated ATPase and dATPase
                     activities; replication protein A stimulates helicase and
                     ATPase activities"
                     /codon_start=1
                     /product="ATP-dependent 5'-3' DNA helicase HCS1"
                     /protein_id="NP_012908.1"
                     /db_xref="GI:6322835"
                     /db_xref="SGD:S000001500"
                     /db_xref="GeneID:853852"
                     /translation="MNKELASKFLSSIKHEREQDIQTTSRLLTTLSIQQLVQNGLAIN
                     NIHLENIRSGLIGKLYMELGPNLAVNDKIQRGDIKVGDIVLVRPAKTKVNTKTKPKVK
                     KVSEDSNGEQAECSGVVYKMSDTQITIALEESQDVIATTFYSYSKLYILKTTNVVTYN
                     RMESTMRKLSEISSPIQDKIIQYLVNERPFIPNTNSFQNIKSFLNPNLNDSQKTAINF
                     AINNDLTIIHGPPGTGKTFTLIELIQQLLIKNPEERILICGPSNISVDTILERLTPLV
                     PNNLLLRIGHPARLLDSNKRHSLDILSKKNTIVKDISQEIDKLIQENKKLKNYKQRKE
                     NWNEIKLLRKDLKKREFKTIKDLIIQSRIVVTTLHGSSSRELCSLYRDDPNFQLFDTL
                     IIDEVSQAMEPQCWIPLIAHQNQFHKLVLAGDNKQLPPTIKTEDDKNVIHNLETTLFD
                     RIIKIFPKRDMVKFLNVQYRMNQKIMEFPSHSMYNGKLLADATVANRLLIDLPTVDAT
                     PSEDDDDTKIPLIWYDTQGDEFQETADEATILGSKYNEGEIAIVKEHIENLRSFNVPE
                     NSIGVISPYNAQVSHLKKLIHDELKLTDIEISTVDGFQGREKDVIILSLVRSNEKFEV
                     GFLKEERRLNVAMTRPRRQLVVVGNIEVLQRCGNKYLKSWSEWCEENADVRYPNIDDY
                     L"
     gene            complement(<407465..>407989)
                     /gene="ATP7"
                     /locus_tag="YKL016C"
                     /db_xref="GeneID:853853"
     mRNA            complement(<407465..>407989)
                     /gene="ATP7"
                     /locus_tag="YKL016C"
                     /product="F1F0 ATP synthase subunit d"
                     /transcript_id="NM_001179582.3"
                     /db_xref="GI:398364744"
                     /db_xref="GeneID:853853"
     CDS             complement(407465..407989)
                     /gene="ATP7"
                     /locus_tag="YKL016C"
                     /note="Subunit d of the stator stalk of mitochondrial F1F0
                     ATP synthase; F1F0 ATP synthase is a large, evolutionarily
                     conserved enzyme complex required for ATP synthesis"
                     /codon_start=1
                     /product="F1F0 ATP synthase subunit d"
                     /protein_id="NP_012909.3"
                     /db_xref="GI:398364745"
                     /db_xref="SGD:S000001499"
                     /db_xref="GeneID:853853"
                     /translation="MSLAKSAANKLDWAKVISSLRITGSTATQLSSFKKRNDEARRQL
                     LELQSQPTEVDFSHYRSVLKNTSVIDKIESYVKQYKPVKIDASKQLQVIESFEKHAMT
                     NAKETESLVSKELKDLQSTLDNIQSARPFDELTVDDLTKIKPEIDAKVEEMVKKGKWD
                     VPGYKDRFGNLNVM"
     gene            <408544..>411483
                     /gene="PUT3"
                     /locus_tag="YKL015W"
                     /db_xref="GeneID:853854"
     mRNA            <408544..>411483
                     /gene="PUT3"
                     /locus_tag="YKL015W"
                     /product="Put3p"
                     /transcript_id="NM_001179581.1"
                     /db_xref="GI:296146361"
                     /db_xref="GeneID:853854"
     CDS             408544..411483
                     /gene="PUT3"
                     /locus_tag="YKL015W"
                     /note="Transcriptional activator; binds specific gene
                     recruitment sequences and is required for DNA zip
                     code-mediated targeting of genes to nuclear periphery;
                     regulates proline utilization genes, constitutively binds
                     PUT1 and PUT2 promoters as a dimer, undergoes
                     conformational change to form active state; binds other
                     promoters only under activating conditions; differentially
                     phosphorylated in presence of different nitrogen sources;
                     has a Zn(2)-Cys(6) binuclear cluster domain"
                     /codon_start=1
                     /product="Put3p"
                     /protein_id="NP_012910.1"
                     /db_xref="GI:6322837"
                     /db_xref="SGD:S000001498"
                     /db_xref="GeneID:853854"
                     /translation="MVTDQGSRHSIQSKQPAYVNKQPQKRQQRSSVACLSCRKRHIKC
                     PGGNPCQKCVTSNAICEYLEPSKKIVVSTKYLQQLQKDLNDKTEENNRLKALLLERPV
                     SVRGKDNSDDDERHINNAPSSDTLEVSSAPAAPIFDLMSNSNTASDNDNDDDNSNRIT
                     NNRSYDHSLEKYYKKAISIFKQPANANGENGNGANGHEDDDEDDEEISTNFAQRSGRL
                     IESHNGFHYFVGSSSMTLFGLEIQSLVTKYISVKNFRPLPINTKNKILNSNLNPAISS
                     FINSNNYLFSSYNFLNPISTIVNLNSINDNLSPLMFKIILKSDTDGSSGQEEVIQFQL
                     PSYNYTKLLIDCFINYNDGCFYFFNEGLVKCGINKLYLENKWLYYDNTKKALDNENDP
                     ILQAVWFCKILLILAVGEMYLGSINNEMLKNYSNQPKLPGSKFFQMGSKIFNCLFSSE
                     RLENVTKKGGIEVLLLYAFFLQVADYTLASYFYFGQALRTCLILGLHVDSQSDTLSRY
                     EIEHHRRLWWTVYMFERMLSSKAGLPLSFTDYTISTALPADIDDETIEEKNSHYVFRK
                     AELISNCVTIVKINAQILSKLYQRQPETNIIITLKVVIKQLLEWRNNLSDSLQVDFTQ
                     KDEDFKISRLSTNMFTEYFQGINLAVRPLLFHFASIQLKRFKTSNTFVNLQNYSATIS
                     SLLTCSLHASVNTIRSLWSLLQNSMLAMFSYMDREYLFTSSCTLLLFNTAFGIHEQTL
                     YHLDHSLEIFTQMRNLGNIPAGLRRAQLLTLMANLDFHGIMNDLITKYNDILKFDSMN
                     CENDNIVEDSNEPKRETEKCKPHKDGDRIDPSIIDCDKSNTNTNMIKNESISNIVSIL
                     PEGAKPTLTDYSNGNNDVNDINVNNSEPSTFFDIITASLENSYQTTLTEKGSQVMEKN
                     MDQLDSVHNLNDDDLQQLLEDLGNIDHSDEKLWKEITDQAMWLGNTMDPTAAAGSEID
                     FTDYLGP"
     gene            complement(<411619..>416913)
                     /gene="URB1"
                     /locus_tag="YKL014C"
                     /gene_synonym="NPA1"
                     /db_xref="GeneID:853855"
     mRNA            complement(<411619..>416913)
                     /gene="URB1"
                     /locus_tag="YKL014C"
                     /gene_synonym="NPA1"
                     /product="Urb1p"
                     /transcript_id="NM_001179580.3"
                     /db_xref="GI:398364754"
                     /db_xref="GeneID:853855"
     CDS             complement(411619..416913)
                     /gene="URB1"
                     /locus_tag="YKL014C"
                     /gene_synonym="NPA1"
                     /note="Protein required for the normal accumulation of 25S
                     and 5.8S rRNAs; nucleolar protein; associated with the
                     27SA2 pre-ribosomal particle; proposed to be involved in
                     the biogenesis of the 60S ribosomal subunit"
                     /codon_start=1
                     /product="Urb1p"
                     /protein_id="NP_012911.3"
                     /db_xref="GI:398364755"
                     /db_xref="SGD:S000001497"
                     /db_xref="GeneID:853855"
                     /translation="MSNHSEAYGSRDQRREKYTQGKEFEDGTLETLESIISAVEDETL
                     SKDYQPLIVFFQRGFGAQLVQTWSYYAQVNNHGKFSKTTSLLTKTLRVLSSDTSTVTI
                     GSGLIRLILTDYTKVLYRGLNNMRAQLTNPILRLLKQIVNFNNGQHIEELVSYFDFSL
                     PILPRLLVPSKSELANGNSSADSSKHDSLRFTFIKFWLTLISNASPFVRKELLTENFK
                     IMSNLFKFMNKADSDKLSEHILSVFINDILKEKSFKRTTKTKILNELAASKIHHFYYS
                     SNKNLVKKANEFFLTFGASRDFSVAFPDNCVWFKNSVADGASHGAPITVNQVEFQIHN
                     KLLFNTLRLFKPWEDTLQLGTLIKILENVPELVAPYSIFLTTNGNYDPKMTSYWFGIT
                     LLINKIINLKIPQFMEKVDSNIPPATSLVIENILPSLLTKSSLVKSLQFETPIIRQLA
                     CQSIVLALKKLEKVSTFYDQKGWRNEKTILLNEFHTRIPDLPIFVSTLSNSLASNKDN
                     RILPLSISIIFNYYSKMFPNLFSINLPSSNIYTDIMQKSKISGIEFAILDNYLQFQEF
                     NSTQTRWWNPSSGGNSLFTLLLKLASSKNASNVITTRISNLLDELTRTNVIFNISLIS
                     PVMALVNSLQGLSLQVSEIDNMEQVWKWFDETISRVVKTPYKYVDMAKEYNYISPFIM
                     CLSEQWKYVDKSGNPEFLIKWLILFLRNMIFIGEDHIGIDKLVKNVFPEVSDHDVNIY
                     LKLDSFEENIKKTNSSNSLISSMKSSSFFQYISALPSKNLMNISRLPVNKLDAAGILF
                     RVQLLVEDDSVVYDNWFEATACELTGKIASYMVTDTEFPIIKVLERYINFALPKLAIE
                     KRNALLMKKSRFMCNLIGAVCFETGHQLVEFREIIQKVVFSGENVEEYANYNELYQKE
                     DVNAFLTSVSEYLSTSALTSLLMCSTKLESTRNILQKLFNEGKTIKISLVKNILNKAA
                     NEDPASIKEVNISLAKFFEENKVCVDASSDPMGKLSLSETTSLINSFVSSDLNYLVLK
                     AFYRWEHFSFPSFIPSIWRIKDSPLLSIVTTAALFKHMQDKDFSAFAHETISKYGNEI
                     AKSTYTTSKSEIFDEILNMITTYIDFYDETKRNEILKCVLSQSDHKYHAATVRYIAAH
                     NNFTYPGVETWLHKTLLYLTKYLSERKVISNSFFELLRAMAELLKLEEVPNKLNVKII
                     NSQLEAILGSEWIKQIKVLEYVIVLIFCVSKKSIQSQRMVQLLLSNDSYSSIMIKDND
                     EDSSYRKFLSTMILFSLFSIDPVVNSTPIVQEKLLTFYSGTISSNDKLILKILETIES
                     HTATSWTNMIFSWEFIKDEEEEILEAIGDTRLITKEREGLILTLQKNMIKKSIDRYVL
                     ERPQVPELYTDSNTNNYDATTRCDLVKKYYDDTERSGVDMYDPLFLLLLIIHNKELVK
                     MVKDDEGNVTYRYEFENFLDCKIFQFIICSLSDCHTVANISYEHLSNLASSLEKKTAQ
                     MNLEKQITSKDNERKESDSDLIKYNSIYQVLIKRILYQRQQNQDPINPLIWFSISRIV
                     DLLGSPTAPLHEKAYRWVLSNSTIRSWDIPMVSDVMMSYNKRQQDDNKKEIDMEIYYG
                     ELSWVLTTICKGIKTDEDYKMLEKKGVFEWLLNLINMPYLKERLRELIYFIFYKVQRV
                     ADDGGLNLISRNGIVSFFEVLNNNIKSRLPQDDILNNIGTLRNENRGTLNTTLRLAQE
                     QNGIEKLLLGYNELVKSQKRLILWTEGDSDNVVKRLRK"
     rep_origin      417185..417417
                     /note="ARS1113;
                     Autonomously Replicating Sequence"
                     /db_xref="SGD:S000118405"
     gene            complement(<417508..>418023)
                     /gene="ARC19"
                     /locus_tag="YKL013C"
                     /db_xref="GeneID:853856"
     mRNA            complement(<417508..>418023)
                     /gene="ARC19"
                     /locus_tag="YKL013C"
                     /product="Arc19p"
                     /transcript_id="NM_001179579.1"
                     /db_xref="GI:296146363"
                     /db_xref="GeneID:853856"
     CDS             complement(417508..418023)
                     /gene="ARC19"
                     /locus_tag="YKL013C"
                     /note="Subunit of the ARP2/3 complex; ARP2/3 is required
                     for the motility and integrity of cortical actin patches"
                     /codon_start=1
                     /product="Arc19p"
                     /protein_id="NP_012912.1"
                     /db_xref="GI:6322839"
                     /db_xref="SGD:S000001496"
                     /db_xref="GeneID:853856"
                     /translation="MSQSLRPYLTAVRYSLEAALTLSNFSSQEVERHNRPEVEVPNTS
                     AELLLQPMHISRNENEQVLIEPSVNSVRMSLMVKQADEIEQILVHKFTRFLEQRAEAF
                     YILRRVPIPGYSISFLITNKHTESMKTGKLVDFIIEFMEDVDKEISEIKLFLNARARF
                     VAEAYLDEFVY"
     gene            <418310..>420061
                     /gene="PRP40"
                     /locus_tag="YKL012W"
                     /db_xref="GeneID:853857"
     mRNA            <418310..>420061
                     /gene="PRP40"
                     /locus_tag="YKL012W"
                     /product="Prp40p"
                     /transcript_id="NM_001179578.3"
                     /db_xref="GI:398364758"
                     /db_xref="GeneID:853857"
     CDS             418310..420061
                     /gene="PRP40"
                     /locus_tag="YKL012W"
                     /note="U1 snRNP protein involved in splicing; interacts
                     with the branchpoint-binding protein during the formation
                     of the second commitment complex"
                     /codon_start=1
                     /product="Prp40p"
                     /protein_id="NP_012913.3"
                     /db_xref="GI:398364759"
                     /db_xref="SGD:S000001495"
                     /db_xref="GeneID:853857"
                     /translation="MSIWKEAKDASGRIYYYNTLTKKSTWEKPKELISQEELLLRENG
                     WKAAKTADGKVYYYNPTTRETSWTIPAFEKKVEPIAEQKHDTVSHAQVNGNRIALTAG
                     EKQEPGRTINEEESQYANNSKLLNVRRRTKEEAEKEFITMLKENQVDSTWSFSRIISE
                     LGTRDPRYWMVDDDPLWKKEMFEKYLSNRSADQLLKEHNETSKFKEAFQKMLQNNSHI
                     KYYTRWPTAKRLIADEPIYKHSVVNEKTKRQTFQDYIDTLIDTQKESKKKLKTQALKE
                     LREYLNGIITTSSSETFITWQQLLNHYVFDKSKRYMANRHFKVLTHEDVLNEYLKIVN
                     TIENDLQNKLNELRLRNYTRDRIARDNFKSLLREVPIKIKANTRWSDIYPHIKSDPRF
                     LHMLGRNGSSCLDLFLDFVDEQRMYIFAQRSIAQQTLIDQNFEWNDADSDEITKQNIE
                     KVLENDRKFDKVDKEDISLIVDGLIKQRNEKIQQKLQNERRILEQKKHYFWLLLQRTY
                     TKTGKPKPSTWDLASKELGESLEYKALGDEDNIRRQIFEDFKPESSAPTAESATANLT
                     LTASKKRHLTPAVELDY"
     gene            complement(<420155..>421216)
                     /gene="CCE1"
                     /locus_tag="YKL011C"
                     /gene_synonym="MGT1"
                     /db_xref="GeneID:853858"
     mRNA            complement(<420155..>421216)
                     /gene="CCE1"
                     /locus_tag="YKL011C"
                     /gene_synonym="MGT1"
                     /product="Cce1p"
                     /transcript_id="NM_001179577.1"
                     /db_xref="GI:296146365"
                     /db_xref="GeneID:853858"
     CDS             complement(420155..421216)
                     /gene="CCE1"
                     /locus_tag="YKL011C"
                     /gene_synonym="MGT1"
                     /EC_number="3.1.-.-"
                     /note="Mitochondrial cruciform cutting endonuclease;
                     cleaves Holliday junctions formed during recombination of
                     mitochondrial DNA; CCE1 has a paralog, MRS1, that arose
                     from the whole genome duplication"
                     /codon_start=1
                     /product="Cce1p"
                     /protein_id="NP_012914.1"
                     /db_xref="GI:6322841"
                     /db_xref="SGD:S000001494"
                     /db_xref="GeneID:853858"
                     /translation="MSTAQKAKILQLIDSCCQNAKSTQLKSLSFVIGAVNGTTKEAKR
                     TYIQEQCEFLEKLRQQKIREGRINILSMDAGVSNFAFSKMQLLNNDPLPKVLDWQKIN
                     LEEKFFQNLKKLSLNPAETSELVFNLTEYLFESMPIPDMFTIERQRTRTMSSRHILDP
                     ILKVNILEQILFSNLENKMKYTNKIPNTSKLRYMVCSSDPHRMTSYWCIPREETPTSS
                     KKLKSNKHSKDSRIKLVKKILSTSILEGNSTSSTKLVEFIGVWNNRIRNALTKKKSFK
                     LCDILEIQDNSGVRKDDDLADSFLHCLSWMEWLKNYESITELLNSKTLVKTQFGQVFE
                     FCENKVQKLKFLQNTYNND"
     gene            complement(<421424..>425875)
                     /gene="UFD4"
                     /locus_tag="YKL010C"
                     /db_xref="GeneID:853859"
     mRNA            complement(<421424..>425875)
                     /gene="UFD4"
                     /locus_tag="YKL010C"
                     /product="putative ubiquitin-protein ligase UFD4"
                     /transcript_id="NM_001179576.3"
                     /db_xref="GI:398364788"
                     /db_xref="GeneID:853859"
     CDS             complement(421424..425875)
                     /gene="UFD4"
                     /locus_tag="YKL010C"
                     /note="Ubiquitin-protein ligase (E3); interacts with Rpt4p
                     and Rpt6p, two subunits of the 19S particle of the 26S
                     proteasome; cytoplasmic E3 involved in the degradation of
                     ubiquitin fusion proteins; relative distribution to the
                     nucleus increases upon DNA replication stress"
                     /codon_start=1
                     /product="putative ubiquitin-protein ligase UFD4"
                     /protein_id="NP_012915.3"
                     /db_xref="GI:398364789"
                     /db_xref="SGD:S000001493"
                     /db_xref="GeneID:853859"
                     /translation="MSENNSHNLDEHESHSENSDYMMDTQVEDDYDEDGHVQGEYSYY
                     PDEDEDEHMLSSVGSFEADDGEDDDNDYHHEDDSGLLYGYHRTQNGSDEDRNEEEDGL
                     ERSHDNNEFGSNPLHLPDILETFAQRLEQRRQTSEGLGQHPVGRTLPEILSMIGGRME
                     RSAESSARNERISKLIENTGNASEDPYIAMESLKELSENILMMNQMVVDRIIPMETLI
                     GNIAAILSDKILREELELQMQACRCMYNLFEVCPESISIAVDEHVIPILQGKLVEISY
                     IDLAEQVLETVEYISRVHGRDILKTGQLSIYVQFFDFLTIHAQRKAIAIVSNACSSIR
                     TDDFKTIVEVLPTLKPIFSNATDQPILTRLVNAMYGICGALHGVDKFETLFSLDLIER
                     IVQLVSIQDTPLENKLKCLDILTVLAMSSDVLSRELREKTDIVDMATRSFQHYSKSPN
                     AGLHETLIYVPNSLLISISRFIVVLFPPEDERILSADKYTGNSDRGVISNQEKFDSLV
                     QCLIPILVEIYTNAADFDVRRYVLIALLRVVSCINNSTAKAINDQLIKLIGSILAQKE
                     TASNANGTYSSEAGTLLVGGLSLLDLICKKFSELFFPSIKREGIFDLVKDLSVDFNNI
                     DLKEDGNENISLSDEEGDLHSSIEECDEGDEEYDYEFTDMEIPDSVKPKKISIHIFRT
                     LSLAYIKNKGVNLVNRVLSQMNVEQEAITEELHQIEGVVSILENPSTPDKTEEDWKGI
                     WSVLKKCIFHEDFDVSGFEFTSTGLASSITKRITSSTVSHFILAKSFLEVFEDCIDRF
                     LEILQSALTRLENFSIVDCGLHDGGGVSSLAKEIKIKLVYDGDASKDNIGTDLSSTIV
                     SVHCIASFTSLNEFLRHRMVRMRFLNSLIPNLTSSSTEADREEEENCLDHMRKKNFDF
                     FYDNEKVDMESTVFGVIFNTFVRRNRDLKTLWDDTHTIKFCKSLEGNNRESEAAEEAN
                     EGKKLRDFYKKREFAQVDTGSSADILTLLDFLHSCGVKSDSFINSKLSAKLARQLDEP
                     LVVASGALPDWSLFLTRRFPFLFPFDTRMLFLQCTSFGYGRLIQLWKNKSKGSKDLRN
                     DEALQQLGRITRRKLRISRKTIFATGLKILSKYGSSPDVLEIEYQEEAGTGLGPTLEF
                     YSVVSKYFARKSLNMWRCNSYSYRSEMDVDTTDDYITTLLFPEPLNPFSNNEKVIELF
                     GYLGTFVARSLLDNRILDFRFSKVFFELLHRMSTPNVTTVPSDVETCLLMIELVDPLL
                     AKSLKYIVANKDDNMTLESLSLTFTVPGNDDIELIPGGCNKSLNSSNVEEYIHGVIDQ
                     ILGKGIEKQLKAFIEGFSKVFSYERMLILFPDELVDIFGRVEEDWSMATLYTNLNAEH
                     GYTMDSSIIHDFISIISAFGKHERRLFLQFLTGSPKLPIGGFKSLNPKFTVVLKHAED
                     GLTADEYLPSVMTCANYLKLPKYTSKDIMRSRLCQAIEEGAGAFLLS"
     gene            <426242..>426952
                     /gene="MRT4"
                     /locus_tag="YKL009W"
                     /db_xref="GeneID:853860"
     mRNA            <426242..>426952
                     /gene="MRT4"
                     /locus_tag="YKL009W"
                     /product="Mrt4p"
                     /transcript_id="NM_001179575.1"
                     /db_xref="GI:296146367"
                     /db_xref="GeneID:853860"
     CDS             426242..426952
                     /gene="MRT4"
                     /locus_tag="YKL009W"
                     /note="Protein involved in mRNA turnover and ribosome
                     assembly; required at post-transcriptional step for
                     efficient retrotransposition; localizes to the nucleolus"
                     /codon_start=1
                     /product="Mrt4p"
                     /protein_id="NP_012916.1"
                     /db_xref="GI:6322843"
                     /db_xref="SGD:S000001492"
                     /db_xref="GeneID:853860"
                     /translation="MPRSKRSKLVTLAQTDKKGRENKERIFDEVREALDTYRYVWVLH
                     LDDVRTPVLQEIRTSWAGSKLIMGKRKVLQKALGEKREEEYKENLYQLSKLCSGVTGL
                     LFTDEDVNTVKEYFKSYVRSDYSRPNTKAPLTFTIPEGIVYSRGGQIPAEEDVPMIHS
                     LEPTMRNKFEIPTKIKAGKITIDSPYLVCTEGEKLDVRQALILKQFGIAASEFKVKVS
                     AYYDNDSSTVESTNINME"
     gene            complement(<427295..>428551)
                     /gene="LAC1"
                     /locus_tag="YKL008C"
                     /gene_synonym="DGT1"
                     /db_xref="GeneID:853861"
     mRNA            complement(<427295..>428551)
                     /gene="LAC1"
                     /locus_tag="YKL008C"
                     /gene_synonym="DGT1"
                     /product="sphingosine N-acyltransferase LAC1"
                     /transcript_id="NM_001179574.3"
                     /db_xref="GI:398364794"
                     /db_xref="GeneID:853861"
     CDS             complement(427295..428551)
                     /gene="LAC1"
                     /locus_tag="YKL008C"
                     /gene_synonym="DGT1"
                     /EC_number="2.3.1.24"
                     /note="Ceramide synthase component; involved in synthesis
                     of ceramide from C26(acyl)-coenzyme A and
                     dihydrosphingosine or phytosphingosine, functionally
                     equivalent to Lag1p; LAC1 has a paralog, LAG1, that arose
                     from the whole genome duplication"
                     /codon_start=1
                     /product="sphingosine N-acyltransferase LAC1"
                     /protein_id="NP_012917.3"
                     /db_xref="GI:398364795"
                     /db_xref="SGD:S000001491"
                     /db_xref="GeneID:853861"
                     /translation="MSTIKPSPSNNNLKVRSRPRRKSSIGKIDLGDTVPSLGTMFETK
                     ESKTAAKRRMQRLSEATKNDSDLVKKIWFSFREISYRHAWIAPLMILIAVYSAYFTSG
                     NTTKTNVLHRFVAVSYQIGDTNAYGKGINDLCFVFYYMIFFTFLREFLMDVVIRPFAI
                     RLHVTSKHRIKRIMEQMYAIFYTGVSGPFGIYCMYHSDLWFFNTKAMYRTYPDFTNPF
                     LFKVFYLGQAAFWAQQACILVLQLEKPRKDHNELTFHHIVTLLLIWSSYVFHFTKMGL
                     PIYITMDVSDFLLSFSKTLNYLDSGLAFFSFAIFVVAWIYLRHYINLKILWSVLTQFR
                     TEGNYVLNFATQQYKCWISLPIVFVLIGALQLVNLYWLFLIFRVLYRILWRGILKDDR
                     SDSESDEESDESSTTPTDSTPTKKDI"
     gene            <429302..>430108
                     /gene="CAP1"
                     /locus_tag="YKL007W"
                     /db_xref="GeneID:853862"
     mRNA            <429302..>430108
                     /gene="CAP1"
                     /locus_tag="YKL007W"
                     /product="Cap1p"
                     /transcript_id="NM_001179573.1"
                     /db_xref="GI:296146369"
                     /db_xref="GeneID:853862"
     CDS             429302..430108
                     /gene="CAP1"
                     /locus_tag="YKL007W"
                     /note="Alpha subunit of the capping protein heterodimer
                     (Cap1p and Cap2p); capping protein (CP) binds to the
                     barbed ends of actin filaments preventing further
                     polymerization; localized predominantly to cortical actin
                     patches; protein increases in abundance and relocalizes
                     from bud neck to plasma membrane upon DNA replication
                     stress"
                     /codon_start=1
                     /product="Cap1p"
                     /protein_id="NP_012918.1"
                     /db_xref="GI:6322845"
                     /db_xref="SGD:S000001490"
                     /db_xref="GeneID:853862"
                     /translation="MSSSKFEEVINKIINDSPPGELREVYDDLIKITSENSKNTILDA
                     IENYNVQNCIPIEVNGNSVIISKYNKEGAKFFDPVNSVIFSVNHLERKGLDIEPYEFT
                     HAKIEKGQLKELHDKLHEYLLQSFPGDVSFAVYPVPEEISKISIIIVSTKYNPNNFWN
                     GHWRSSYIYDLETRELSGQISTQVHYYEDGNVSFQSGKDINQSNVDDVVCTIRDIETN
                     FENDLDLSFFDLNEKQFKALRRRLPVTRSKINWGSAIGSYRLGKNAAEGK"
     gene            complement(<430198..>430632)
                     /gene="SFT1"
                     /locus_tag="YKL006C-A"
                     /db_xref="GeneID:853863"
     mRNA            complement(join(<430198..430455,430597..>430632))
                     /gene="SFT1"
                     /locus_tag="YKL006C-A"
                     /product="Sft1p"
                     /transcript_id="NM_001180028.3"
                     /db_xref="GI:398364812"
                     /db_xref="GeneID:853863"
     CDS             complement(join(430198..430455,430597..430632))
                     /gene="SFT1"
                     /locus_tag="YKL006C-A"
                     /note="Intra-Golgi v-SNARE; required for transport of
                     proteins between an early and a later Golgi compartment"
                     /codon_start=1
                     /product="Sft1p"
                     /protein_id="NP_012919.3"
                     /db_xref="GI:398364813"
                     /db_xref="SGD:S000002101"
                     /db_xref="GeneID:853863"
                     /translation="MSNSRYSQTESNNDRKLEGLANKLATFRNINQEIGDRAVSDSSV
                     INQMTDSLGSMFTDIKNSSSRLTRSLKAGNSIWRMVGLALLIFFILYTLFKLF"
     gene            complement(431030..431138)
                     /locus_tag="snR87"
                     /db_xref="GeneID:9164916"
     ncRNA           complement(431030..431138)
                     /locus_tag="snR87"
                     /ncRNA_class="snoRNA"
                     /product="SNR87"
                     /note="C/D box small nucleolar RNA (snoRNA); guides
                     2'-O-methylation of small subunit (SSU) rRNA at position
                     A436"
                     /transcript_id="NR_132202.1"
                     /db_xref="GI:831416127"
                     /db_xref="SGD:S000114301"
                     /db_xref="GeneID:9164916"
     gene            <431906..>432720
                     /gene="RPL14A"
                     /locus_tag="YKL006W"
                     /db_xref="GeneID:853864"
     mRNA            join(<431906..432034,432433..>432720)
                     /gene="RPL14A"
                     /locus_tag="YKL006W"
                     /product="ribosomal 60S subunit protein L14A"
                     /transcript_id="NM_001179572.1"
                     /db_xref="GI:296146371"
                     /db_xref="GeneID:853864"
     CDS             join(431906..432034,432433..432720)
                     /gene="RPL14A"
                     /locus_tag="YKL006W"
                     /note="Ribosomal 60S subunit protein L14A; N-terminally
                     acetylated; homologous to mammalian ribosomal protein L14,
                     no bacterial homolog; RPL14A has a paralog, RPL14B, that
                     arose from the whole genome duplication"
                     /codon_start=1
                     /product="ribosomal 60S subunit protein L14A"
                     /protein_id="NP_012920.1"
                     /db_xref="GI:6322847"
                     /db_xref="SGD:S000001489"
                     /db_xref="GeneID:853864"
                     /translation="MSTDSIVKASNWRLVEVGRVVLIKKGQSAGKLAAIVEIIDQKKV
                     LIDGPKAGVPRQAINLGQVVLTPLTFALPRGARTATVSKKWAAAAVCEKWAASSWAKK
                     IAQRERRAALTDFERFQVMVLRKQKRYTVKKALAKA"
     gene            complement(<433093..>434877)
                     /gene="BYE1"
                     /locus_tag="YKL005C"
                     /db_xref="GeneID:853865"
     mRNA            complement(<433093..>434877)
                     /gene="BYE1"
                     /locus_tag="YKL005C"
                     /product="Bye1p"
                     /transcript_id="NM_001179571.3"
                     /db_xref="GI:398364820"
                     /db_xref="GeneID:853865"
     CDS             complement(433093..434877)
                     /gene="BYE1"
                     /locus_tag="YKL005C"
                     /note="Negative regulator of transcription elongation;
                     contains a TFIIS-like domain that associates with
                     chromatin and a PHD domain that interacts with H3K4me3;
                     multicopy suppressor of temperature-sensitive ess1
                     mutations, binds RNA polymerase II large subunit"
                     /codon_start=1
                     /product="Bye1p"
                     /protein_id="NP_012921.3"
                     /db_xref="GI:398364821"
                     /db_xref="SGD:S000001488"
                     /db_xref="GeneID:853865"
                     /translation="MSVRTSSRSNKGQNKYIEYLLQEETEAPKKKRTKKKVDSAIEKN
                     KKSDSSQEPRKDTENVRTDEVDEADEGYVRCLCGANNENYDAAEYSHGDMVQCDGCDT
                     WQHIKCMTDGKDTIDGLMSEDSKYYCELCDPSLYAHLETSKEAEVSEDEDYHDDVYKP
                     VNDHDDNDADVFLDEESPRKRKRSPDSAKGIHIKSKQVKKSNGSKKRNKSIDAAKSDT
                     AENEMPTRKDFESEKEHKLRYNAEKMFSTLFSKFIVPETIEAKLYELPDGKDVISISQ
                     EFAHNLEEELYKACLNVEFGTLDKIYTEKVRSLYSNLKDKKNLELKAHVVEGKLPLNK
                     LVNMNASELANPDLQEFKEKRDKIILENFIVEVPDKPMYVKTHKGDELIEDIAEPQED
                     ILYSKDSIRLHNIDSIDSDKSKIEQTHAISKEPSPSTIINEESLNCAFLYPGLGLEFT
                     GYLNYIGASQKLRRDIFKEAIGDGKLYVEGRLPTTTAAPYLKEISCSRAILVYQLFPS
                     NDSESKTTFADVVDSLENKGRIAGIKPKTRYEKDFYIVPSKGGEIPEILKDILGSHND
                     ERSERFSRMKSDERTLFAFVVVKQEFIH"
     gene            <435580..>436785
                     /gene="AUR1"
                     /locus_tag="YKL004W"
                     /db_xref="GeneID:853866"
     mRNA            <435580..>436785
                     /gene="AUR1"
                     /locus_tag="YKL004W"
                     /product="inositol phosphorylceramide synthase"
                     /transcript_id="NM_001179570.1"
                     /db_xref="GI:296146373"
                     /db_xref="GeneID:853866"
     CDS             435580..436785
                     /gene="AUR1"
                     /locus_tag="YKL004W"
                     /EC_number="2.-.-.-"
                     /note="Phosphatidylinositol:ceramide phosphoinositol
                     transferase; required for sphingolipid synthesis; can
                     mutate to confer aureobasidin A resistance; also known as
                     IPC synthase"
                     /codon_start=1
                     /product="inositol phosphorylceramide synthase"
                     /protein_id="NP_012922.1"
                     /db_xref="GI:6322849"
                     /db_xref="SGD:S000001487"
                     /db_xref="GeneID:853866"
                     /translation="MANPFSRWFLSERPPNCHVADLETSLDPHQTLLKVQKYKPALSD
                     WVHYIFLGSIMLFVFITNPAPWIFKILFYCFLGTLFIIPATSQFFFNALPILTWVALY
                     FTSSYFPDDRRPPITVKVLPAVETILYGDNLSDILATSTNSFLDILAWLPYGLFHFGA
                     PFVVAAILFVFGPPTVLQGYAFAFGYMNLFGVIMQNVFPAAPPWYKILYGLQSANYDM
                     HGSPGGLARIDKLLGINMYTTAFSNSSVIFGAFPSLHSGCATMEALFFCYCFPKLKPL
                     FIAYVCWLWWSTMYLTHHYFVDLMAGSVLSYVIFQYTKYTHLPIVDTSLFCRWSYTSI
                     EKYDISKSDPLAADSNDIESVPLSNLELDFDLNMTDEPSVSPSLFDGSTSVSRSSATS
                     ITSLGVKRA"
     gene            complement(<437097..>437492)
                     /gene="MRP17"
                     /locus_tag="YKL003C"
                     /db_xref="GeneID:853867"
     mRNA            complement(<437097..>437492)
                     /gene="MRP17"
                     /locus_tag="YKL003C"
                     /product="mitochondrial 37S ribosomal protein YmS16"
                     /transcript_id="NM_001179569.3"
                     /db_xref="GI:398364830"
                     /db_xref="GeneID:853867"
     CDS             complement(437097..437492)
                     /gene="MRP17"
                     /locus_tag="YKL003C"
                     /note="Mitochondrial ribosomal protein of the small
                     subunit; MRP17 exhibits genetic interactions with PET122,
                     encoding a COX3-specific translational activator"
                     /codon_start=1
                     /product="mitochondrial 37S ribosomal protein YmS16"
                     /protein_id="NP_012923.3"
                     /db_xref="GI:398364831"
                     /db_xref="SGD:S000001486"
                     /db_xref="GeneID:853867"
                     /translation="MLYELIGLVRITNSNAPKLEAKELSSTIGKLIIQNRGVVRDIVP
                     MGIRYLPKIMKKDQEKHFRAYHFLMLFDSSAAVQSEILRTLKKDPRVIRSSIVKVDLD
                     KQLDRASSLHRSLGKKSILELVNEDYQSI"
     gene            <437778..>438544
                     /gene="DID4"
                     /locus_tag="YKL002W"
                     /gene_synonym="CHM2; GRD7; REN1; VPL2; VPS14; VPS2; VPT14"
                     /db_xref="GeneID:853868"
     mRNA            join(<437778..437837,437906..>438544)
                     /gene="DID4"
                     /locus_tag="YKL002W"
                     /gene_synonym="CHM2; GRD7; REN1; VPL2; VPS14; VPS2; VPT14"
                     /product="ESCRT-III subunit protein DID4"
                     /transcript_id="NM_001179568.1"
                     /db_xref="GI:296146375"
                     /db_xref="GeneID:853868"
     CDS             join(437778..437837,437906..438544)
                     /gene="DID4"
                     /locus_tag="YKL002W"
                     /gene_synonym="CHM2; GRD7; REN1; VPL2; VPS14; VPS2; VPT14"
                     /note="Class E Vps protein of the ESCRT-III complex;
                     required for sorting of integral membrane proteins into
                     lumenal vesicles of multivesicular bodies, and for
                     delivery of newly synthesized vacuolar enzymes to the
                     vacuole, involved in endocytosis"
                     /codon_start=1
                     /product="ESCRT-III subunit protein DID4"
                     /protein_id="NP_012924.2"
                     /db_xref="GI:9755336"
                     /db_xref="SGD:S000001485"
                     /db_xref="GeneID:853868"
                     /translation="MSLFEWVFGKNVTPQERLKKNQRALERTQRELEREKRKLELQDK
                     KLVSEIKKSAKNGQVAAAKVQAKDLVRTRNYIQKFDNMKAQLQAISLRIQAVRSSDQM
                     TRSMSEATGLLAGMNRTMNLPQLQRISMEFEKQSDLMGQRQEFMDEAIDNVMGDEVDE
                     DEEADEIVNKVLDEIGVDLNSQLQSTPQNLVSNAPIAETAMGIPEPIGAGSEFHGNPD
                     DDLQARLNTLKKQT"
     gene            complement(<438777..>439385)
                     /gene="MET14"
                     /locus_tag="YKL001C"
                     /db_xref="GeneID:853869"
     mRNA            complement(<438777..>439385)
                     /gene="MET14"
                     /locus_tag="YKL001C"
                     /product="adenylyl-sulfate kinase"
                     /transcript_id="NM_001179567.3"
                     /db_xref="GI:398364836"
                     /db_xref="GeneID:853869"
     CDS             complement(438777..439385)
                     /gene="MET14"
                     /locus_tag="YKL001C"
                     /EC_number="2.7.1.25"
                     /note="Adenylylsulfate kinase; required for sulfate
                     assimilation and involved in methionine metabolism"
                     /codon_start=1
                     /product="adenylyl-sulfate kinase"
                     /protein_id="NP_012925.3"
                     /db_xref="GI:398364837"
                     /db_xref="SGD:S000001484"
                     /db_xref="GeneID:853869"
                     /translation="MATNITWHPNLTYDERKALRKQDGCTIWLTGLSASGKSTIACAL
                     EQLLLQKNLSAYRLDGDNIRFGLNKDLGFSEKDRNENIRRISEVSKLFADSCAISITS
                     FISPYRVDRDRARELHKEAGLKFIEIFVDVPLEVAEQRDPKGLYKKAREGVIKEFTGI
                     SAPYEAPKAPELHLRTDQKTVEECATIIYEYLISEKIIRKHL"
     centromere      complement(440129..440246)
                     /note="CEN11; Chromosome XI centromere"
                     /db_xref="SGD:S000006472"
     centromere      complement(440129..440153)
                     /note="CEN11_CDEIII of CEN11"
     centromere      complement(440154..440236)
                     /note="CEN11_CDEII of CEN11"
     centromere      complement(440237..440246)
                     /note="CEN11_CDEI of CEN11"
     gene            complement(<440608..>442722)
                     /gene="VPS1"
                     /locus_tag="YKR001C"
                     /gene_synonym="GRD1; LAM1; SPO15; VPL1; VPT26"
                     /db_xref="GeneID:853870"
     mRNA            complement(<440608..>442722)
                     /gene="VPS1"
                     /locus_tag="YKR001C"
                     /gene_synonym="GRD1; LAM1; SPO15; VPL1; VPT26"
                     /product="dynamin-like GTPase VPS1"
                     /transcript_id="NM_001179791.1"
                     /db_xref="GI:296146377"
                     /db_xref="GeneID:853870"
     CDS             complement(440608..442722)
                     /gene="VPS1"
                     /locus_tag="YKR001C"
                     /gene_synonym="GRD1; LAM1; SPO15; VPL1; VPT26"
                     /note="Dynamin-like GTPase required for vacuolar sorting;
                     also involved in actin cytoskeleton organization,
                     endocytosis, late Golgi-retention of some proteins,
                     regulation of peroxisome biogenesis"
                     /codon_start=1
                     /product="dynamin-like GTPase VPS1"
                     /protein_id="NP_012926.1"
                     /db_xref="GI:6322853"
                     /db_xref="SGD:S000001709"
                     /db_xref="GeneID:853870"
                     /translation="MDEHLISTINKLQDALAPLGGGSQSPIDLPQITVVGSQSSGKSS
                     VLENIVGRDFLPRGTGIVTRRPLVLQLINRRPKKSEHAKVNQTANELIDLNINDDDKK
                     KDESGKHQNEGQSEDNKEEWGEFLHLPGKKFYNFDEIRKEIVKETDKVTGANSGISSV
                     PINLRIYSPHVLTLTLVDLPGLTKVPVGDQPPDIERQIKDMLLKYISKPNAIILSVNA
                     ANTDLANSDGLKLAREVDPEGTRTIGVLTKVDLMDQGTDVIDILAGRVIPLRYGYIPV
                     INRGQKDIEHKKTIREALENERKFFENHPSYSSKAHYCGTPYLAKKLNSILLHHIRQT
                     LPEIKAKIEATLKKYQNELINLGPETMDSASSVVLSMITDFSNEYAGILDGEAKELSS
                     QELSGGARISYVFHETFKNGVDSLDPFDQIKDSDIRTIMYNSSGSAPSLFVGTEAFEV
                     LVKQQIRRFEEPSLRLVTLVFDELVRMLKQIISQPKYSRYPALREAISNQFIQFLKDA
                     TIPTNEFVVDIIKAEQTYINTAHPDLLKGSQAMVMVEEKLHPRQVAVDPKTGKPLPTQ
                     PSSSKAPVMEEKSGFFGGFFSTKNKKKLAALESPPPVLKATGQMTERETMETEVIKLL
                     ISSYFSIVKRTIADIIPKALMLKLIVKSKTDIQKVLLEKLYGKQDIEELTKENDITIQ
                     RRKECKKMVEILRNASQIVSSV"
     gene            <443232..>444938
                     /gene="PAP1"
                     /locus_tag="YKR002W"
                     /db_xref="GeneID:853871"
     mRNA            <443232..>444938
                     /gene="PAP1"
                     /locus_tag="YKR002W"
                     /product="polynucleotide adenylyltransferase PAP1"
                     /transcript_id="NM_001179792.3"
                     /db_xref="GI:398364848"
                     /db_xref="GeneID:853871"
     CDS             443232..444938
                     /gene="PAP1"
                     /locus_tag="YKR002W"
                     /EC_number="2.7.7.19"
                     /note="Poly(A) polymerase; one of three factors required
                     for mRNA 3'-end polyadenylation, forms multiprotein
                     complex with polyadenylation factor I (PF I), also
                     required for mRNA nuclear export; may also polyadenylate
                     rRNAs; required for gene looping"
                     /codon_start=1
                     /product="polynucleotide adenylyltransferase PAP1"
                     /protein_id="NP_012927.3"
                     /db_xref="GI:398364849"
                     /db_xref="SGD:S000001710"
                     /db_xref="GeneID:853871"
                     /translation="MSSQKVFGITGPVSTVGATAAENKLNDSLIQELKKEGSFETEQE
                     TANRVQVLKILQELAQRFVYEVSKKKNMSDGMARDAGGKIFTYGSYRLGVHGPGSDID
                     TLVVVPKHVTREDFFTVFDSLLRERKELDEIAPVPDAFVPIIKIKFSGISIDLICARL
                     DQPQVPLSLTLSDKNLLRNLDEKDLRALNGTRVTDEILELVPKPNVFRIALRAIKLWA
                     QRRAVYANIFGFPGGVAWAMLVARICQLYPNACSAVILNRFFIILSEWNWPQPVILKP
                     IEDGPLQVRVWNPKIYAQDRSHRMPVITPAYPSMCATHNITESTKKVILQEFVRGVQI
                     TNDIFSNKKSWANLFEKNDFFFRYKFYLEITAYTRGSDEQHLKWSGLVESKVRLLVMK
                     LEVLAGIKIAHPFTKPFESSYCCPTEDDYEMIQDKYGSHKTETALNALKLVTDENKEE
                     ESIKDAPKAYLSTMYIGLDFNIENKKEKVDIHIPCTEFVNLCRSFNEDYGDHKVFNLA
                     LRFVKGYDLPDEVFDENEKRPSKKSKRKNLDARHETVKRSKSDAASGDNINGTTAAVD
                     VN"
     gene            <445381..>446727
                     /gene="OSH6"
                     /locus_tag="YKR003W"
                     /db_xref="GeneID:853872"
     mRNA            <445381..>446727
                     /gene="OSH6"
                     /locus_tag="YKR003W"
                     /product="oxysterol-binding protein OSH6"
                     /transcript_id="NM_001179793.1"
                     /db_xref="GI:296146379"
                     /db_xref="GeneID:853872"
     CDS             445381..446727
                     /gene="OSH6"
                     /locus_tag="YKR003W"
                     /note="Member of an oxysterol-binding protein family;
                     overlapping, redundant functions in sterol metabolism and
                     which collectively perform a function essential for
                     viability; GFP-fusion protein localizes to the cell
                     periphery; overexpression extends lifespan by promoting
                     vacuolar fusion; OSH6 has a paralog, OSH7, that arose from
                     the whole genome duplication"
                     /codon_start=1
                     /product="oxysterol-binding protein OSH6"
                     /protein_id="NP_012928.1"
                     /db_xref="GI:6322855"
                     /db_xref="SGD:S000001711"
                     /db_xref="GeneID:853872"
                     /translation="MGSKKLTVGSDSHRLSKSSFSSNKSSHSATKDQPIDTDDIDEDD
                     ESGHNIILNIISQLRPGCDLTRITLPTFILEKKSMLERVTNQLQFPEFLLQAHSEKDP
                     LKRFLYVMKWYLAGWHIAPKAVKKPLNPVLGEYFTAYWDLPNKQQAYYISEQTSHHPP
                     ECAYFYMIPESSIRVDGVVIPKSRFLGNSSAAMMDGSTVLQFLDIKDGNGKPEKYVLT
                     QPNVYVRGILFGKMRIELGDHMIIKSPNFQADIEFKTKGYVFGTYDAIEGTVKDYDGN
                     AYYEISGKWNDVMYLKDLKQPRSSPKVFLDTHKESPLRPKVRPLSEQGEYESRKLWKK
                     VTDALAVRNHPVATEEKFQIEDHQRQLAKKRIEDGVEFHPKLFRRSKPGEDLDYCIYK
                     NIPVDEDPEKQIRSILQIAPILPGQQFTDKFFIPAFEKIKSQKKMIENEKQNPAKQ"
     gene            complement(<446799..>448036)
                     /gene="ECM9"
                     /locus_tag="YKR004C"
                     /gene_synonym="YKR004C-A"
                     /db_xref="GeneID:853873"
     mRNA            complement(join(<446799..447706,447811..>448036))
                     /gene="ECM9"
                     /locus_tag="YKR004C"
                     /gene_synonym="YKR004C-A"
                     /product="Ecm9p"
                     /transcript_id="NM_001179794.3"
                     /db_xref="GI:398364860"
                     /db_xref="GeneID:853873"
     CDS             complement(join(446799..447706,447811..448036))
                     /gene="ECM9"
                     /locus_tag="YKR004C"
                     /gene_synonym="YKR004C-A"
                     /note="Non-essential hypothetical protein"
                     /codon_start=1
                     /product="Ecm9p"
                     /protein_id="NP_012929.4"
                     /db_xref="GI:398364861"
                     /db_xref="SGD:S000001712"
                     /db_xref="GeneID:853873"
                     /translation="MQSSLPLCREFFEKITAYLDYHDFRLTITANQPSITLPYYVDEK
                     AHSIELIIFKTTFLSLFQEAHTYFNKTFSDQSGISNENIYYMTVGFLLTTPENKTVYN
                     VHEDLLKRYFQDNSVLVIPDLLVKEVRLIQRLLCSSNNRINKSSSLWILYRKLFVLSL
                     DANTLVLPDILFVFHSSGSQHFSNYYCWNTARWFYDNLPYNKRIELFNLTKRFCFQNV
                     KDCSSWSALAYMVCQQEEKKTDNIRDFQRLTSSFNVPFKINKVDLNFQVQPADAFTQE
                     LVKWIDRTYAADWPPYLCLLQITKFNITLRIEMDSVLLTWRNEILNFEENSGHIKMIN
                     NTPIVPEKFSNDLLTSVNFAHFGYKKLFLNKFLDKNKKEQSDS"
     rep_origin      448020..448254
                     /note="ARS1114;
                     Autonomously Replicating Sequence"
                     /db_xref="SGD:S000118406"
     gene            complement(<448521..>450167)
                     /locus_tag="YKR005C"
                     /db_xref="GeneID:853874"
     mRNA            complement(join(<448521..449951,450021..>450167))
                     /locus_tag="YKR005C"
                     /product="hypothetical protein"
                     /transcript_id="NM_001179795.1"
                     /db_xref="GI:296146381"
                     /db_xref="GeneID:853874"
     CDS             complement(join(448521..449951,450021..450167))
                     /locus_tag="YKR005C"
                     /codon_start=1
                     /product="hypothetical protein"
                     /protein_id="NP_012930.2"
                     /db_xref="GI:157285914"
                     /db_xref="SGD:S000001713"
                     /db_xref="GeneID:853874"
                     /translation="MLECLSALLVLFAGGGGSVLAAVQSKTVADPNLCPGYNSQLISP
                     FLSSCKRNLSECVSRYFDEQYAFCRSCVTVNNETMEDLDNCKCLQCALSSLNNSCFHD
                     YCTSKDEYDKLQIVVEQFQLTNGVLDDGEILKPRGNKFSSRKLSYFVGQNNTLFRNPL
                     QFEKNQLISALLTSLTNNQKTISSVDMFEVVDANNEVQYLRERTISGKTLSPATGYEE
                     ENDGDCSVKDKKWEGKIEYHENKKVSSENCSKDTDDKSGSKKERNTKAPLFHTATEIH
                     MTRWSSWRPKKIFTRYLVNEYQSPKIITTVNRFYRTKTDTETGTTLITSTKAKRRWFP
                     RTKIVTSTATSTFLSITTTTTTNAIATKSLVAVLNPDGLNKKAGINFGLFSANGELAS
                     PDEGGTPTVVRRDKISDPGAANEQATLFSTTFSQVPHLPELDSGEFISAASQLDKRIF
                     IFTAITVSITTLMMLGFSYRSRVSFRDHSIDDSDDDNDWSDDEVEFDEEYFYSLPVSI
                     PEKGISLDKMAQQLGVE"
     gene            complement(<450423..>451217)
                     /gene="MRPL13"
                     /locus_tag="YKR006C"
                     /gene_synonym="YK105"
                     /db_xref="GeneID:853875"
     mRNA            complement(<450423..>451217)
                     /gene="MRPL13"
                     /locus_tag="YKR006C"
                     /gene_synonym="YK105"
                     /product="mitochondrial 54S ribosomal protein YmL13"
                     /transcript_id="NM_001179796.3"
                     /db_xref="GI:398364874"
                     /db_xref="GeneID:853875"
     CDS             complement(450423..451217)
                     /gene="MRPL13"
                     /locus_tag="YKR006C"
                     /gene_synonym="YK105"
                     /note="Mitochondrial ribosomal protein of the large
                     subunit; not essential for mitochondrial translation"
                     /codon_start=1
                     /product="mitochondrial 54S ribosomal protein YmL13"
                     /protein_id="NP_012931.4"
                     /db_xref="GI:398364875"
                     /db_xref="SGD:S000001714"
                     /db_xref="GeneID:853875"
                     /translation="MSSLLKLHCIRPLPQRSVWLSGYKQKARCIHSSAANGDFMSWFK
                     RKKQEEHQEPVKDTKQLIKDIEEGTNEASSQSSSNNKNRLELIPENFIGEGSRRCKRQ
                     KELKLAVSSAPFNQWLSRDKITSDNQLDDMILQATEKTLGKVDQDVQFSDLVAKFQFT
                     KFLQSKSGYLIPDYELTTLSTPLQFKRYIKEKILPSANDPKLAYKEAEPNAIHPFSDN
                     YASPNIYVVNDVTSKEQKSKYDTIMKEIQKLEDDATRKALETARSA"
     gene            <451434..>451988
                     /gene="MEH1"
                     /locus_tag="YKR007W"
                     /gene_synonym="EGO1; GSE2"
                     /db_xref="GeneID:853876"
     mRNA            <451434..>451988
                     /gene="MEH1"
                     /locus_tag="YKR007W"
                     /gene_synonym="EGO1; GSE2"
                     /product="Meh1p"
                     /transcript_id="NM_001179797.1"
                     /db_xref="GI:296146383"
                     /db_xref="GeneID:853876"
     CDS             451434..451988
                     /gene="MEH1"
                     /locus_tag="YKR007W"
                     /gene_synonym="EGO1; GSE2"
                     /note="Component of the EGO and GSE complexes; EGO is
                     involved in the regulation of microautophagy and GSE is
                     required for proper sorting of amino acid permease Gap1p;
                     loss results in a defect in vacuolar acidification"
                     /codon_start=1
                     /product="Meh1p"
                     /protein_id="NP_012932.1"
                     /db_xref="GI:6322859"
                     /db_xref="SGD:S000001715"
                     /db_xref="GeneID:853876"
                     /translation="MGAVLSCCRNHSGEENEALLREQQAGYGSQGNANDEYDAEQMRL
                     KEHEHEQKLLAREQELRDIVANTNDKLIDISMINNSGIVIQGTDLQEALDKRQQEEGG
                     DSREDERSAGDDNLSGHSVPSSGSAQATTHQTAPRTNTFTLLTSPDSAKISKEQLKKL
                     HSNILNEIFSQSQVNKPGPLTVPF"
     gene            <452201..>454078
                     /gene="RSC4"
                     /locus_tag="YKR008W"
                     /db_xref="GeneID:853877"
     mRNA            <452201..>454078
                     /gene="RSC4"
                     /locus_tag="YKR008W"
                     /product="Rsc4p"
                     /transcript_id="NM_001179798.4"
                     /db_xref="GI:398364888"
                     /db_xref="GeneID:853877"
     CDS             452201..454078
                     /gene="RSC4"
                     /locus_tag="YKR008W"
                     /note="Component of the RSC chromatin remodeling complex;
                     found in close proximity to nucleosomal DNA; displaced
                     from the surface of nucleosomal DNA after chromatin
                     remodeling; acetylated (K25) by Gcn5p, altering
                     replication stress tolerance; contains tandem bromodomains
                     that recognize histone H3 acetylated on K14 (H3K14ac) by
                     Gcn5p"
                     /codon_start=1
                     /product="Rsc4p"
                     /protein_id="NP_012933.4"
                     /db_xref="GI:398364889"
                     /db_xref="SGD:S000001716"
                     /db_xref="GeneID:853877"
                     /translation="MVVKKRKLATEAGGSDERPKYLPGKHPKNQEKTPHVDYNAPLNP
                     KSELFLDDWHIPKFNRFISFTLDVLIDKYKDIFKDFIKLPSRKFHPQYYYKIQQPMSI
                     NEIKSRDYEYEDGPSNFLLDVELLTKNCQAYNEYDSLIVKNSMQVVMLIEFEVLKAKN
                     LKRNYLINSEVKAKLLHYLNKLVDATEKKINQALLGASSPKNLDDKVKLSEPFMELVD
                     KDELPEYYEIVHSPMALSIVKQNLEIGQYSKIYDFIIDMLLVFQNAHIFNDPSALIYK
                     DATTLTNYFNYLIQKEFFPELQDLNERGEINLEFDKFEFENYLAIGGGGPAAAGALAI
                     SALDNDIEPESNREDLIDQADYDFNHFEGLGNGYNRSLLTEDYLLNPNNFKKLIAKPE
                     TVQSEVKNERSTTSDIEKTNSLESEHLKIPKYNVIKSMQKEMQSLSEQHTMEYKPYKL
                     IQQIYIFSSKNLYSQATKPLLGSRPSCNQNWVEYIFNGNELSQNENAFSFMLQPMQTF
                     LTLQSHLTSSLKDTETLLTINKEPVKSRTSNVNSNLSQPQQQENDVIGNDTKQDIENL
                     TIGGGNNNDIVGNDNDKRNNITEIFDIRLSEGLNHLMFRCEDKISHETEFMNFWINVL
                     P"
     gene            complement(<454352..>457054)
                     /gene="FOX2"
                     /locus_tag="YKR009C"
                     /gene_synonym="POX2"
                     /db_xref="GeneID:853878"
     mRNA            complement(<454352..>457054)
                     /gene="FOX2"
                     /locus_tag="YKR009C"
                     /gene_synonym="POX2"
                     /product="bifunctional hydroxyacyl-CoA
                     dehydrogenase/enoyl-CoA hydratase FOX2"
                     /transcript_id="NM_001179799.1"
                     /db_xref="GI:296146385"
                     /db_xref="GeneID:853878"
     CDS             complement(454352..457054)
                     /gene="FOX2"
                     /locus_tag="YKR009C"
                     /gene_synonym="POX2"
                     /EC_number="1.1.1.n12"
                     /EC_number="4.2.1.119"
                     /note="3-hydroxyacyl-CoA dehydrogenase and enoyl-CoA
                     hydratase; multifunctional enzyme of the peroxisomal fatty
                     acid beta-oxidation pathway"
                     /codon_start=1
                     /product="bifunctional hydroxyacyl-CoA
                     dehydrogenase/enoyl-CoA hydratase FOX2"
                     /protein_id="NP_012934.1"
                     /db_xref="GI:6322861"
                     /db_xref="SGD:S000001717"
                     /db_xref="GeneID:853878"
                     /translation="MPGNLSFKDRVVVITGAGGGLGKVYALAYASRGAKVVVNDLGGT
                     LGGSGHNSKAADLVVDEIKKAGGIAVANYDSVNENGEKIIETAIKEFGRVDVLINNAG
                     ILRDVSFAKMTEREFASVVDVHLTGGYKLSRAAWPYMRSQKFGRIINTASPAGLFGNF
                     GQANYSAAKMGLVGLAETLAKEGAKYNINVNSIAPLARSRMTENVLPPHILKQLGPEK
                     IVPLVLYLTHESTKVSNSIFELAAGFFGQLRWERSSGQIFNPDPKTYTPEAILNKWKE
                     ITDYRDKPFNKTQHPYQLSDYNDLITKAKKLPPNEQGSVKIKSLCNKVVVVTGAGGGL
                     GKSHAIWFARYGAKVVVNDIKDPFSVVEEINKLYGEGTAIPDSHDVVTEAPLIIQTAI
                     SKFQRVDILVNNAGILRDKSFLKMKDEEWFAVLKVHLFSTFSLSKAVWPIFTKQKSGF
                     IINTTSTSGIYGNFGQANYAAAKAAILGFSKTIALEGAKRGIIVNVIAPHAETAMTKT
                     IFSEKELSNHFDASQVSPLVVLLASEELQKYSGRRVIGQLFEVGGGWCGQTRWQRSSG
                     YVSIKETIEPEEIKENWNHITDFSRNTINPSSTEESSMATLQAVQKAHSSKELDDGLF
                     KYTTKDCILYNLGLGCTSKELKYTYENDPDFQVLPTFAVIPFMQATATLAMDNLVDNF
                     NYAMLLHGEQYFKLCTPTMPSNGTLKTLAKPLQVLDKNGKAALVVGGFETYDIKTKKL
                     IAYNEGSFFIRGAHVPPEKEVRDGKRAKFAVQNFEVPHGKVPDFEAEISTNKDQAALY
                     RLSGDFNPLHIDPTLAKAVKFPTPILHGLCTLGISAKALFEHYGPYEELKVRFTNVVF
                     PGDTLKVKAWKQGSVVVFQTIDTTRNVIVLDNAAVKLSQAKSKL"
     LTR             complement(458140..458471)
                     /note="Ty1 LTR"
                     /db_xref="SGD:S000007058"
     gene            458557..458670
                     /locus_tag="tL(CAA)K"
                     /db_xref="GeneID:853879"
     tRNA            join(458557..458594,458627..458670)
                     /locus_tag="tL(CAA)K"
                     /product="tRNA-Leu"
                     /note="Leucine tRNA (tRNA-Leu), predicted by tRNAscan-SE
                     analysis"
                     /db_xref="SGD:S000006642"
                     /db_xref="GeneID:853879"
     gene            complement(<458924..>461239)
                     /gene="TOF2"
                     /locus_tag="YKR010C"
                     /db_xref="GeneID:853880"
     mRNA            complement(<458924..>461239)
                     /gene="TOF2"
                     /locus_tag="YKR010C"
                     /product="Tof2p"
                     /transcript_id="NM_001179800.3"
                     /db_xref="GI:398364904"
                     /db_xref="GeneID:853880"
     CDS             complement(458924..461239)
                     /gene="TOF2"
                     /locus_tag="YKR010C"
                     /note="Protein required for rDNA silencing and mitotic
                     rDNA condensation; stimulates Cdc14p phosphatase activity
                     and biphasic release to promote rDNA repeat segregation;
                     required for condensin recruitment to the replication fork
                     barrier site; TOF2 has a paralog, NET1, that arose from
                     the whole genome duplication"
                     /codon_start=1
                     /product="Tof2p"
                     /protein_id="NP_012935.3"
                     /db_xref="GI:398364905"
                     /db_xref="SGD:S000001718"
                     /db_xref="GeneID:853880"
                     /translation="MIKMWRLQIVLVPPSAQDIITFLEARLNTPQSVSPMVQYNEDII
                     THNNSINNCSDPSPTSPSSQNSIQSNRSSDFINYLPNCKKFLHFTDGDNTLLQLSNEI
                     LTKFDRLYPNFKESIEIVSLQDRHGCDLDSEFIIKDVFENDGVVLVILKDELDWSRNQ
                     HISLLQLARQRRRQDNKPSTKSIVTEKRKKISKEDLSSISNKDTMHLIAKSSLKNNFI
                     NKSRVSTPLMNEILPLASKYDALNKEKCPMPLTSTVVASNVHKDVKDHARAKEGVVTQ
                     GSDNNKENIPSSTQQQKNDGAKRAESKDLDLLRNSSEDADYEPADENSPQISFDSIDT
                     DFQLSTTSHTNSDMHIQYSNPSSGAHSPRKSSLEIKVQNKKGDDLPLNDKDIGENCRR
                     IEAFSDEEDFNETDNDRADSFINNSKKASMGFRDINSDLDSVSFNSDIENAVQSTQST
                     KNVVSPPFFPEKELNNRLHQSQGKEALFRLVEKEFPDKSLGAASSTSHAKDVKIQETI
                     RKLNRFKPTGETKVQKRNSITEPYYGKFGIMKKDKPKSITSKGVSLETKHFDDPNTII
                     SGEKFAKFGKIKVKRKTDDVGSKVIEFKRKRNMGNRSLKDIFANAGKPPNAASTIKVV
                     KLMRDPVDNSKDKVEATSNSTAQEQEQVSPKLPVMNSTPGKRKNGQAIPSSLERTPQL
                     KKVKVTRSHSSPSSSSSMSLESSLDSSSSDDSDDDSDSRNVQVKKINFKTSHGPAGNS
                     NGKPMLDVDDNEINTKKYQTPKYVESDEDDQ"
     gene            complement(<461635..>462696)
                     /locus_tag="YKR011C"
                     /db_xref="GeneID:853881"
     mRNA            complement(<461635..>462696)
                     /locus_tag="YKR011C"
                     /product="hypothetical protein"
                     /transcript_id="NM_001179801.1"
                     /db_xref="GI:296146387"
                     /db_xref="GeneID:853881"
     CDS             complement(461635..462696)
                     /locus_tag="YKR011C"
                     /note="hypothetical protein; green fluorescent protein
                     (GFP)-fusion protein localizes to the nucleus; protein
                     abundance increases in response to DNA replication stress"
                     /codon_start=1
                     /product="hypothetical protein"
                     /protein_id="NP_012936.1"
                     /db_xref="GI:6322863"
                     /db_xref="SGD:S000001719"
                     /db_xref="GeneID:853881"
                     /translation="MSKLETVYLYAGEEQPRVKLTCIKEGLTLTQVIKFVHSIQELYG
                     IELQTSETITENLKIDCAPAYLKPNCIPHFYILEYEEISDTFFIWKSDGRWQLNKLSA
                     LLYVDNDANVVKNTSWKEVFQNDQRFKNYDKRAWLQNCLEKMNRDLSKLNVEQFWSQY
                     DKICQSIAKQKKKQEQFNMEVFDNFKNIVSIAIIKTKVLSNKRLLTTTLKNYHNSMKK
                     KYNIQEQNLKENSLASCSNNEPSASLESESRHFSPVNSLSPSSLSTDDEAVSTDYIYK
                     GPESKPNVNFMHSSATNDLIKSNFESYFKLMAEDYETFDLRAWSRQRPRKFQLVEKKK
                     ITKNPPNSHHPHKNGKISF"
     rep_origin      462699..463742
                     /note="ARS1115;
                     Putative replication origin; identified in multiple array
                     studies, not yet confirmed by plasmid-based assay"
                     /db_xref="SGD:S000130139"
     gene            <463959..>464948
                     /gene="PRY2"
                     /locus_tag="YKR013W"
                     /gene_synonym="YFW12"
                     /db_xref="GeneID:853882"
     mRNA            <463959..>464948
                     /gene="PRY2"
                     /locus_tag="YKR013W"
                     /gene_synonym="YFW12"
                     /product="Pry2p"
                     /transcript_id="NM_001179803.3"
                     /db_xref="GI:398364918"
                     /db_xref="GeneID:853882"
     CDS             463959..464948
                     /gene="PRY2"
                     /locus_tag="YKR013W"
                     /gene_synonym="YFW12"
                     /note="Sterol binding protein involved in the export of
                     acetylated sterols; secreted glycoprotein and member of
                     the CAP protein superfamily (cysteine-rich secretory
                     proteins (CRISP), antigen 5, and pathogenesis related 1
                     proteins); sterol export function is redundant with that
                     of PRY1; may be involved in detoxification of hydrophobic
                     compounds; PRY2 has a paralog, PRY1, that arose from the
                     whole genome duplication"
                     /codon_start=1
                     /product="Pry2p"
                     /protein_id="NP_012938.3"
                     /db_xref="GI:398364919"
                     /db_xref="SGD:S000001721"
                     /db_xref="GeneID:853882"
                     /translation="MKFSKVSLLAASASVALSAPVAVTVTQHVHQAATVVVQGIVRVE
                     NGQTLTTFITKGTQTASASPVATTSAPIVVANAQVDSIATSVIQESAVVAESATFEES
                     STETSEAFSTATATIQAVQTSASATQDDVTTTLTSSTQPTSTTTPTTTTTSPTTTTSP
                     TTTASPTTTASPTTATTTQSTASSTQSSSSDFSTSMVNEHNTKRALHKDTGSLTWSDT
                     LATYAQNYADSYDCSGNLVHSGGPYGENLALGYGTTGSVDAWYNEITSYDYSNPGFSE
                     SAGHFTQVVWKGTSEVGCGLKSCGGEWGDYIICSYKAAGNVIGEFADNVMPLA"
     gene            complement(<465367..>466071)
                     /gene="YPT52"
                     /locus_tag="YKR014C"
                     /db_xref="GeneID:853884"
     mRNA            complement(<465367..>466071)
                     /gene="YPT52"
                     /locus_tag="YKR014C"
                     /product="Rab family GTPase YPT52"
                     /transcript_id="NM_001179804.1"
                     /db_xref="GI:296146389"
                     /db_xref="GeneID:853884"
     CDS             complement(465367..466071)
                     /gene="YPT52"
                     /locus_tag="YKR014C"
                     /note="Endosomal Rab family GTPase; required for vacuolar
                     protein sorting, endocytosis and multivesicular body (MVB)
                     biogenesis and sorting; required for localization of the
                     CORVET complex to endosomes; involved in autophagy and
                     ionic stress tolerance; similar to Vps21p and Ypt53p;
                     mammalian Rab5 homolog; protein abundance increases in
                     response to DNA replication stress"
                     /codon_start=1
                     /product="Rab family GTPase YPT52"
                     /protein_id="NP_012939.1"
                     /db_xref="GI:6322866"
                     /db_xref="SGD:S000001722"
                     /db_xref="GeneID:853884"
                     /translation="MLQFKLVLLGDSSVGKSSIVHRFVKDTFDELRESTIGAAFLSQS
                     ITIHPNDGNETKDVVIKFEIWDTAGQERYKSLAPMYYRNANAALVVYDITQEDSLQKA
                     RNWVDELKNKVGDDDLVIYLLGNKVDLCQETPSTETSPDSNEGGDEEQKVRAISTEEA
                     KQYAQEQGLLFREVSAKTGEGVKEIFQDIGEKLYDLKKDEILSKQNRQIGGGNNGQVD
                     INLQRPSTNDPTSCCS"
     gene            complement(<466961..>468667)
                     /locus_tag="YKR015C"
                     /db_xref="GeneID:853885"
     mRNA            complement(<466961..>468667)
                     /locus_tag="YKR015C"
                     /product="hypothetical protein"
                     /transcript_id="NM_001179805.3"
                     /db_xref="GI:398364928"
                     /db_xref="GeneID:853885"
     CDS             complement(466961..468667)
                     /locus_tag="YKR015C"
                     /codon_start=1
                     /product="hypothetical protein"
                     /protein_id="NP_012940.3"
                     /db_xref="GI:398364929"
                     /db_xref="SGD:S000001723"
                     /db_xref="GeneID:853885"
                     /translation="MFLDYSGYEALTEINSSFGKYVLLLQQFEGCRSLKDRLQMLKDL
                     GREFMIFENLNVEDFRESKNMIHRFYTMVISLRQIMEIGPLVRRSPAVLVVEFDCPVE
                     DCLDELDPLHPLNRAFIFIHKQWTYYHQYYIVEKVKKVILDMAPVKEDDWSILHKVVY
                     SEGFVERRYKKKKYLGDIYIPQPLMKSNKITTISNFSQLTKISNVRVYRFNATAACDP
                     QNLNKKNLSIKELKDKDLPNLIWTLEPEKFYVDMRPYKEHEERKKRREEEAKVRMQGE
                     EQENIMIERKKMDSIEVEASSGLKNIIKTPLANRVVNTFNNCAAVVIGYVTEVDKVKD
                     DNEEKNNDRPKIANDGIAQKSRSESEDNAGTPMENAYFQPEPQDNDQNNISWNTTMKD
                     IDPIYMSERCARVWRKEQQMLGLEKAQTFEKKYCKDQMVMDENQVEEPGKHSERHTKN
                     QVVRPRTKIASSASKNDNSNNKNSKSCKNCHKEEAHGLVREYLKIKLNISPHGERNQR
                     TKDKRKCIMKYNASSNNINKMPGESEVLGSTILTDIHFKDVVTVKFRDFKAKFRKVKI
                     NA"
     gene            <469717..>471339
                     /gene="MIC60"
                     /locus_tag="YKR016W"
                     /gene_synonym="AIM28; FCJ1; FMP13"
                     /db_xref="GeneID:853886"
     mRNA            <469717..>471339
                     /gene="MIC60"
                     /locus_tag="YKR016W"
                     /gene_synonym="AIM28; FCJ1; FMP13"
                     /product="Mic60p"
                     /transcript_id="NM_001179806.1"
                     /db_xref="GI:296146391"
                     /db_xref="GeneID:853886"
     CDS             469717..471339
                     /gene="MIC60"
                     /locus_tag="YKR016W"
                     /gene_synonym="AIM28; FCJ1; FMP13"
                     /note="Component of the MICOS complex; MICOS (formerly
                     MINOS or MitOS) is a mitochondrial inner membrane complex
                     that extends into the intermembrane space and has a role
                     in the maintenance of crista junctions, inner membrane
                     architecture, and formation of contact sites to the outer
                     membrane; Mic60p is also involved in import of
                     intermembrane space (IMS) proteins, probably by
                     positioning Mia40p relative to the TOM complex to receive
                     incoming proteins; ortholog of mammalian mitofilin"
                     /codon_start=1
                     /product="Mic60p"
                     /protein_id="NP_012941.1"
                     /db_xref="GI:6322868"
                     /db_xref="SGD:S000001724"
                     /db_xref="GeneID:853886"
                     /translation="MMLRTTASRKIVLRRGLASINTGTTVASKKASHKFRNTLWTIAL
                     SATAFYAGGIIYSQKNDKFGDFFSNNVPFAEDLLETYEHYHDRPTLFLEDSWDGLKAK
                     SNDLLSGLTGSSQTRRSNRENIEVKKILSLEPLNIETENSDPQLKEIIGSLNDLINSL
                     NDSNLSIPESEFNSIKKSNQNMLTNLSQLNETLKEALSNYMIQRTSEVITELNTQYEN
                     SKREFEKNLQKNLLQEVDEFKENLTKQKDKELEEKLKANEELLQAKHANEVGLLSITQ
                     VKEFNKIIKDKIEKERNGRLAHLEEINSEVNDLSKSIDRSSKILSKNEALVQLTFQVD
                     EIKSRINNNNLPDVNIDKELSRLKLLSNLLSTFNKKSCCDDGDCCSCKKGNKNEGKEG
                     KISCKCKPKTNPPSLLSVALDELESTCSGKKILSNEQIYNRWNLLADDFKTASLLPPN
                     SGILGQLTAKVFSLFLFTKTGNPSNATDFDSVYARVGDNLRVSNLNDAVEEVVSLKGW
                     PHKVCESWIEDARRKLEVQRLVEILDCEIRTL"
     gene            complement(<471694..>473349)
                     /gene="HEL1"
                     /locus_tag="YKR017C"
                     /db_xref="GeneID:853887"
     mRNA            complement(<471694..>473349)
                     /gene="HEL1"
                     /locus_tag="YKR017C"
                     /product="E3 ubiquitin-protein ligase HEL1"
                     /transcript_id="NM_001179807.3"
                     /db_xref="GI:398364948"
                     /db_xref="GeneID:853887"
     CDS             complement(471694..473349)
                     /gene="HEL1"
                     /locus_tag="YKR017C"
                     /EC_number="6.3.2.-"
                     /note="RING finger ubiquitin ligase (E3); involved in
                     ubiquitylation and degradation of excess histones;
                     interacts with Ubc4p and Rad53p; null mutant sensitive to
                     hydroxyurea (HU)"
                     /codon_start=1
                     /product="E3 ubiquitin-protein ligase HEL1"
                     /protein_id="NP_012942.3"
                     /db_xref="GI:398364949"
                     /db_xref="SGD:S000001725"
                     /db_xref="GeneID:853887"
                     /translation="MSSGTENDQFYSFDESDSSSIELYESHNTSEFTIHGLVFPKLIS
                     VTSQDSEFDINEDEDGVDTIYEGMLDAPLTKNNKRILCEGSVPNLSYECLTTKGIFER
                     MLQRVDHLQPIFAIPSADILILLQHYDWNEERLLEVWTEKMDELLVELGLSTTANIKK
                     DNDYNSHFREVEFKNDFTCIICCDKKDTETFALECGHEYCINCYRHYIKDKLHEGNII
                     TCMDCSLALKNEDIDKVMGHPSSSKLMDSSIKSFVQKHNRNYKWCPFADCKSIVHLRD
                     TSSLPEYTRLHYSPFVKCNSFHRFCFNCGFEVHSPADCKITTAWVKKARKESEILNWV
                     LSHTKECPKCSVNIEKNGGCNHMVCSSCKYEFCWICEGPWAPHGKNFFQCTMYKNNED
                     NKSKNPQDANKTLKKYTFYYRLFNEHEVSAKLDWNLGQTLGTKVHALQERIGISWIDG
                     QFLSESLKVLNEGRTVLKWSFAVAYYSDASHNLTKIFVDNQMLLANAVESLSELLQIK
                     TPEVIMKRRPEFYNKAGYVENRTTALMECGRELLCKGICKAAE"
     gene            complement(<473723..>475900)
                     /locus_tag="YKR018C"
                     /db_xref="GeneID:853888"
     mRNA            complement(<473723..>475900)
                     /locus_tag="YKR018C"
                     /product="hypothetical protein"
                     /transcript_id="NM_001179808.1"
                     /db_xref="GI:296146393"
                     /db_xref="GeneID:853888"
     CDS             complement(473723..475900)
                     /locus_tag="YKR018C"
                     /note="hypothetical protein; green fluorescent protein
                     (GFP)-fusion protein localizes to the cytoplasm and
                     nucleus; protein abundance increases in response to DNA
                     replication stress; YKR018C has a paralog, IML2, that
                     arose from the whole genome duplication"
                     /codon_start=1
                     /product="hypothetical protein"
                     /protein_id="NP_012943.1"
                     /db_xref="GI:6322870"
                     /db_xref="SGD:S000001726"
                     /db_xref="GeneID:853888"
                     /translation="MFKVFGFGAKEEIPELSQEEKTKAILKQAHDFEQALRAMDYVLD
                     DNADEGLALLDESDAKEASDQTINALARGVIEFLEATLGFEAEEMKKASATLAKAEAL
                     SLKSRERAQKIGLKSSSLYPPGTVYAVTYTESCLLHALLMIFSESMMEAAKAILKLRK
                     SYYMLQEILETIKAANKAKKLKITSGSEDKESTPATFITGGDAFNSVDIPYELTPEEQ
                     KDKDLLQFAEQIHSMRTERLSGAHIGNSPAINRLRGELGLQAMEDLPEEEITDHKVLS
                     DDIDLSQATIDEFVHSGVNLCFGILQVVISLLPPAIGAVLSVVGFRGSREEGLRLVWK
                     ATKQRNVHGCIGLLALMFYYDGPFQFTDDDFDIPAAVKDSSNSEDSEDEEMDGPTLLH
                     PGKILEDALLQSRALFPNSALWLLNEARMLSGKGRLEEAVALMDSIDVSKIRMRQVKS
                     LMIFDRAITLIHLHQYDRAAEDILSLLDISDWSHAFYTYFAGCCYLENWRMCEMGLMK
                     SDKKDEYQKKAEELIFTSVNLLGKKTFKSKNLPLDRFILRKVEQFKAKKEELGVENPL
                     DGIATSPVHEIAYFYNGYNRMSEEHLELTKKMLTEYRNPAIEALDSDQELIKDLLVSL
                     TLRRLGHIQEGCDILDEKVLPKFFSIQNGKVKYIKKTEDPWAYPTALYERALFTWKLE
                     GMDGLPESKEWLLRAQGYADDYELSTRVGMKIKAAIDRVDHSL"
     gene            complement(<476216..>478063)
                     /gene="IRS4"
                     /locus_tag="YKR019C"
                     /db_xref="GeneID:853889"
     mRNA            complement(<476216..>478063)
                     /gene="IRS4"
                     /locus_tag="YKR019C"
                     /product="Irs4p"
                     /transcript_id="NM_001179809.3"
                     /db_xref="GI:398364960"
                     /db_xref="GeneID:853889"
     CDS             complement(476216..478063)
                     /gene="IRS4"
                     /locus_tag="YKR019C"
                     /note="EH domain-containing protein; involved in
                     regulating phosphatidylinositol 4,5-bisphosphate levels
                     and autophagy; Irs4p and Tax4p bind and activate the
                     PtdIns phosphatase Inp51p; Irs4p and Tax4p are involved in
                     localizing Atg17p to the PAS; IRS4 has a paralog, TAX4,
                     that arose from the whole genome duplication"
                     /codon_start=1
                     /product="Irs4p"
                     /protein_id="NP_012944.3"
                     /db_xref="GI:398364961"
                     /db_xref="SGD:S000001727"
                     /db_xref="GeneID:853889"
                     /translation="MRLSFGKQRYHGGTTVTLTEQGASDSLRAAQAIFQNHSNEVSSP
                     CPPVTVSRNPQTRLSEPSLQKSGRKQEQKKARIRTKQVPKIKTTAPNDVELSKKHRSS
                     PAGKDNVSSTAQMAAALAHSQSKLSSDNNSSHSSALDTLKVLETPNLNGLLGIHSRSS
                     SRNGSNESLTPGQRTPDNRSQENLLTSFSSGRRLSSSSMEPATNKDSNKALPKRRPSP
                     PLQSSLVGSGQLHENENLSSISIDSRHSLNPDTSDVISNRSQTSLSQTINQLSLCESE
                     PSIASSNTTTTTSNQGSGLPNLVPNYSSDMRKKKLVNKFKRKVFGSKPKHLSSQYEMD
                     ASSEELGQHEQQPSMRFKTTLRKTSVSTNAENDHASSLHEGNLRYKYNPSNDTYDVYD
                     DTDSDSESDQNQDALTKPRKRDRIKRKIRNSANKTAHHRPIHRTRDRKFNEDKPWKSH
                     TDITFVTDNERKRYESMWVSNRHRHLNLLSWWPSITGDSGAINTLPEDGLILGIIVRD
                     IWKRSNLPNSLLAEIYTKVDTRKDGTLDRKSFIVGMWLVDQCLYGRKLPNVVEQCVWD
                     SVDRYASTTVVPVSTLKAMAKQKRKQMKEEIKNIKKENRVVLVDHNSSS"
     gene            <478338..>478832
                     /gene="VPS51"
                     /locus_tag="YKR020W"
                     /gene_synonym="API3; VPS67; WHI6"
                     /db_xref="GeneID:853890"
     mRNA            <478338..>478832
                     /gene="VPS51"
                     /locus_tag="YKR020W"
                     /gene_synonym="API3; VPS67; WHI6"
                     /product="Vps51p"
                     /transcript_id="NM_001179810.1"
                     /db_xref="GI:296146395"
                     /db_xref="GeneID:853890"
     CDS             478338..478832
                     /gene="VPS51"
                     /locus_tag="YKR020W"
                     /gene_synonym="API3; VPS67; WHI6"
                     /note="Component of the GARP (Golgi-associated retrograde
                     protein) complex; GARP is required for the recycling of
                     proteins from endosomes to the late Golgi, and for mitosis
                     after DNA damage induced checkpoint arrest; links the
                     (VFT/GARP) complex to the SNARE Tlg1p; members of the GARP
                     complex are Vps51p-Vps52p-Vps53p-Vps54p"
                     /codon_start=1
                     /product="Vps51p"
                     /protein_id="NP_012945.1"
                     /db_xref="GI:6322872"
                     /db_xref="SGD:S000001728"
                     /db_xref="GeneID:853890"
                     /translation="MAEQISHKKSLRVSSLNKDRRLLLREFYNLENEPNKGRQEARIG
                     EKASEAHSGEEQVTDVNIDTEANTEKPVKDDELSATEEDLKEGSEDAEEEIKNLPFKR
                     LVQIHNKLLGKETETNNSIKNTIYENYYDLIKVNDLLKEITNANEDQINKLKQTVESL
                     IKEL"
     gene            <479234..>481981
                     /gene="ALY1"
                     /locus_tag="YKR021W"
                     /gene_synonym="ART6"
                     /db_xref="GeneID:853891"
     mRNA            <479234..>481981
                     /gene="ALY1"
                     /locus_tag="YKR021W"
                     /gene_synonym="ART6"
                     /product="Aly1p"
                     /transcript_id="NM_001179811.4"
                     /db_xref="GI:398364976"
                     /db_xref="GeneID:853891"
     CDS             479234..481981
                     /gene="ALY1"
                     /locus_tag="YKR021W"
                     /gene_synonym="ART6"
                     /note="Alpha arrestin, substrate of calcineurin; controls
                     nutrient-mediated intracellular sorting of permease Gap1p;
                     interacts with AP-1 subunit Apl4p; dephosphorylation of
                     Aly1p required for the endocytosis of Dip5p; may regulate
                     endocytosis of plasma membrane proteins by recruiting
                     ubiquitin ligase Rsp5p to plasma membrane targets; ALY1
                     has a paralog, ALY2, that arose from the whole genome
                     duplication"
                     /codon_start=1
                     /product="Aly1p"
                     /protein_id="NP_012946.3"
                     /db_xref="GI:398364977"
                     /db_xref="SGD:S000001729"
                     /db_xref="GeneID:853891"
                     /translation="MLQFNTENDTVAPVFPMEQDINAAPDAVPLVQTTTLQVFVKLAE
                     PIVFLKGFETNGLSEIAPSILRGSLIVRVLKPNKLKSISITFKGISRTEWPEGIPPKR
                     EEFSDVETVVNHTWPFYQADDGMNSFTLEHHSSNNSSNRPSMSDEDYLLEKSGASVYI
                     PPTAEPPKDNSNLSLDAYERNSLSSDNLSNKPVSSDVSHDDSKLLAIQKTPLPSSSRR
                     GSVPANFHGNSLSPHTFISDLFTKTFSNSGATPSPEQEDNYLTPSKDSKEVFIFRPGD
                     YIYTFEQPISQSYPESIKANFGSVEYKLSIDIERFGAFKSTIHTQLPIKVVRLPSDGS
                     VEETEAIAISKDWKDLLHYDVVIFSKEIVLNAFLPIDFHFAPLDKVTLHRIRIYLTES
                     MEYTCNSNGNHEKARRLEPTKKFLLAEHNGPKLPHIPAGSNPLKAKNRGNILLDEKSG
                     DLVNKDFQFEVFVPSKFTNSIRLHPDTNYDKIKAHHWIKICLRLSKKYGDNRKHFEIS
                     IDSPIHILNQLCSHANTLLPSYESHFQYCDEDGNFAPAADQQNYASHHDSNIFFPKEV
                     LSSPVLSPNVQKMNIRIPSDLPVVRNRAESVKKSKSDNTSKKNDQSSNVFASKQLVAN
                     IYKPNQIPRELTSPQALPLSPITSPILNYQPLSNSPPPDFDFDLAKRGAADSHAIPVD
                     PPSYFDVLKADGIELPYYDTSSSKIPELKLNKSRETLASIEEDSFNGWSQIDDLSDED
                     DNDGDIASGFNFKLSTSAPSENVNSHTPILQSLNMSLDGRKKNRASLHATSVLPSTIR
                     QNNQHFNDINQMLGSSDEDAFPKSQSLNFNKKLPILKINDNVIQSNSNSNNRVDNPED
                     TVDSSVDITAFYDPRMSSDSKFDWEVSKNHVDPAAYSVNVASENRVLDDFKKAFREKR
                     K"
     gene            complement(<482171..>483139)
                     /gene="NTR2"
                     /locus_tag="YKR022C"
                     /db_xref="GeneID:853892"
     mRNA            complement(<482171..>483139)
                     /gene="NTR2"
                     /locus_tag="YKR022C"
                     /product="Ntr2p"
                     /transcript_id="NM_001179812.1"
                     /db_xref="GI:296146397"
                     /db_xref="GeneID:853892"
     CDS             complement(482171..483139)
                     /gene="NTR2"
                     /locus_tag="YKR022C"
                     /note="Essential protein that forms a dimer with Ntr1p;
                     also forms a trimer, with Ntr2p and the DExD/H-box RNA
                     helicase Prp43p, that is involved in spliceosome
                     disassembly"
                     /codon_start=1
                     /product="Ntr2p"
                     /protein_id="NP_012947.1"
                     /db_xref="GI:6322874"
                     /db_xref="SGD:S000001730"
                     /db_xref="GeneID:853892"
                     /translation="MAIKKRNKIRLPSGSPEEVGIDGSAHKPMQQIKPLVSNDSEDDD
                     NDICVLQPIKFKKVPKRDITFDGEQAIKEDNSHYEDLYHSKKNTNASTRNKDDLLILN
                     MEDLMEGNHHLLSDSSEAGSSSEGEHISSIPTRGEIAKLKAQKSLSRRKISESDVTTE
                     RDYVKLLDSEDKREIMETIRLNGGLKRNNEKEITNFSDDEMQGFQDEMLALTDNQIAI
                     QKDSKRKIIEKAINEVPYRTNEEWETQLLSKGNINKSNEKIITPLPVLFPDDDESGNS
                     IERINEMVSKICLQRKKVEMRLQALEKTKIDLEKSKASLINKLIGN"
     gene            <483419..>485011
                     /locus_tag="YKR023W"
                     /db_xref="GeneID:853893"
     mRNA            <483419..>485011
                     /locus_tag="YKR023W"
                     /product="hypothetical protein"
                     /transcript_id="NM_001179813.3"
                     /db_xref="GI:398364988"
                     /db_xref="GeneID:853893"
     CDS             483419..485011
                     /locus_tag="YKR023W"
                     /note="hypothetical protein; the authentic, non-tagged
                     protein is detected in highly purified mitochondria in
                     high-throughput studies"
                     /codon_start=1
                     /product="hypothetical protein"
                     /protein_id="NP_012948.3"
                     /db_xref="GI:398364989"
                     /db_xref="SGD:S000001731"
                     /db_xref="GeneID:853893"
                     /translation="MTRKQAIDYAIKQVPQILPLEESDVKALCEQVLSTSSDDPEQIA
                     SKFLEFLGHEDLSFEFVMKFNELLNQNDKKEEKKTKNVHLEHTAPTSWKNESKQPTNN
                     YINKKGDEKPKKLKDEKKSSTTRPTVQPSNQSTQSNPIKEKKEHRSKGKLQSLQEIDE
                     AIKMLELRDSGSSKNCNCQGTRHPVFDIAPNCLHCGKVVCVIEGLNKGKCGHCHEQLI
                     SDNERTQMVEILNQEKNELNGSSSSLSNASNGANVPKKKTKTYKITSGMGKNLFAEQD
                     KLFDFIERKRERERKRNEVLKLQEEKEESEAKERQASEHDHKAEENPELLAAQERLDR
                     LLYFQDTSAERTKIIDNASDFDMNQEVGLWGSARERALALKKQQRNLRKWEKVEKERN
                     GRREKYVVSMNIGSNGKVTMTEVPKDTENVIAGSDDDISDISDEEDISDLKHIHALKS
                     EINTTKSLENLHLQSKAWDYERDKKQFDRPTYVKKNSDTAQQNRKTEEKAHDMQAYDL
                     KSRVQVDQNADASVEQNILAVL"
     gene            complement(<485144..>487372)
                     /gene="DBP7"
                     /locus_tag="YKR024C"
                     /db_xref="GeneID:853894"
     mRNA            complement(<485144..>487372)
                     /gene="DBP7"
                     /locus_tag="YKR024C"
                     /product="Dbp7p"
                     /transcript_id="NM_001179814.1"
                     /db_xref="GI:296146399"
                     /db_xref="GeneID:853894"
     CDS             complement(485144..487372)
                     /gene="DBP7"
                     /locus_tag="YKR024C"
                     /EC_number="3.6.4.13"
                     /note="Putative ATP-dependent RNA helicase of the DEAD-box
                     family; involved in ribosomal biogenesis; required at
                     post-transcriptional step for efficient
                     retrotransposition; essential for growth under anaerobic
                     conditions"
                     /codon_start=1
                     /product="Dbp7p"
                     /protein_id="NP_012949.1"
                     /db_xref="GI:6322876"
                     /db_xref="SGD:S000001732"
                     /db_xref="GeneID:853894"
                     /translation="MSDEDSMLLNFTTNEDTAGSSYKQAAKVTGGRWKDRRRMKMKLE
                     GKTVSRKRKANTTGDEGIIPGRGENSIKKLHKESSYSSEEQEKYKGRNAHNTQGRTLP
                     ADSQFVSSLFTSNREITTAVNTNIHDENVAINPSNAPLKGDQFASLGVSSLLVSHLEQ
                     KMRIKKPTSIQKQAIPQIIGNAGKNDFFIHAQTGSGKTLSYLLPIISTILNMDTHVDR
                     TSGAFALVIAPTRELASQIYHVCSTLVSCCHYLVPCLLIGGERKKSEKARLRKGCNFI
                     IGTPGRVLDHLQNTKVIKEQLSQSLRYIVLDEGDKLMELGFDETISEIIKIVHDIPIN
                     SEKFPKLPHKLVHMLCSATLTDGVNRLRNVALKDYKLISNGTKKDSDIVTVAPDQLLQ
                     RITIVPPKLRLVTLAATLNNITKDFIASGQQSKTLRTIVFVSCSDSVEFHYDAFSGSD
                     GHHKNLTGDSVRLLTKGNTMFPCFSDSRDPDVVIYKLHGSLSQQMRTSTLQHFARDNE
                     ATKGKHLIMFCTDVASRGLDLPHVGSVIELDPPFAVEDHLHRVGRTARAGEKGESLLF
                     LLPGEEEKYMDYIQPYHPMGWELLKFDKEILMPAFKDVNVNRNDKFIRKDEKSSKNKD
                     VGDKEYEWDTNATTWHLNIERRVVGDSAFKNLAVKGFISHVRAYATHISQEKKFFNVK
                     FLHLGHLAKSFGLRERPKAMGLQSSKDGNSEKKPTKENSKNKMFRMARMAEKQIASEF
                     NY"
     gene            <487770..>488618
                     /gene="RPC37"
                     /locus_tag="YKR025W"
                     /db_xref="GeneID:853895"
     mRNA            <487770..>488618
                     /gene="RPC37"
                     /locus_tag="YKR025W"
                     /product="Rpc37p"
                     /transcript_id="NM_001179815.3"
                     /db_xref="GI:398365012"
                     /db_xref="GeneID:853895"
     CDS             487770..488618
                     /gene="RPC37"
                     /locus_tag="YKR025W"
                     /note="RNA polymerase III subunit C37"
                     /codon_start=1
                     /product="Rpc37p"
                     /protein_id="NP_012950.3"
                     /db_xref="GI:398365013"
                     /db_xref="SGD:S000001733"
                     /db_xref="GeneID:853895"
                     /translation="MSIDNKLFVTEEDEEDRTQDRADVEDESNDIDMIADENGTNSAI
                     ANEQEEKSEEVKAEDDTGEEEEDDPVIEEFPLKISGEEESLHVFQYANRPRLVGRKPA
                     EHPFISAARYKPKSHLWEIDIPLDEQAFYNKDKAESEWNGVNVQTLKGVGVENNGQYA
                     AFVKDMQVYLVPIERVAQLKPFFKYIDDANVTRKQEDARRNPNPSSQRAQVVTMSVKS
                     VNDPSQNRLTGSLLAHKVADEEANIELTWAEGTFEQFKDTIVKEAEDKTLVALEKQED
                     YIDNLV"
     gene            complement(<488738..>489655)
                     /gene="GCN3"
                     /locus_tag="YKR026C"
                     /gene_synonym="AAS2"
                     /db_xref="GeneID:853896"
     mRNA            complement(<488738..>489655)
                     /gene="GCN3"
                     /locus_tag="YKR026C"
                     /gene_synonym="AAS2"
                     /product="translation initiation factor eIF2B subunit
                     alpha"
                     /transcript_id="NM_001179816.1"
                     /db_xref="GI:296146401"
                     /db_xref="GeneID:853896"
     CDS             complement(488738..489655)
                     /gene="GCN3"
                     /locus_tag="YKR026C"
                     /gene_synonym="AAS2"
                     /note="Alpha subunit of translation initiation factor
                     eIF2B; guanine-nucleotide exchange factor for eIF2;
                     activity subsequently regulated by phosphorylated eIF2;
                     positive regulator of GCN4 expression; assembles into
                     filaments with Gcd2p, Gcd6p, Gcd7p, and Sui2p as cells
                     approach stationary phase and under cytosolic
                     acidification and starvation conditions"
                     /codon_start=1
                     /product="translation initiation factor eIF2B subunit
                     alpha"
                     /protein_id="NP_012951.1"
                     /db_xref="GI:6322878"
                     /db_xref="SGD:S000001734"
                     /db_xref="GeneID:853896"
                     /translation="MSEFNITETYLRFLEEDTEMTMPIAAIEALVTLLRIKTPETAAE
                     MINTIKSSTEELIKSIPNSVSLRAGCDIFMRFVLRNLHLYGDWENCKQHLIENGQLFV
                     SRAKKSRNKIAEIGVDFIADDDIILVHGYSRAVFSLLNHAANKFIRFRCVVTESRPSK
                     QGNQLYTLLEQKGIPVTLIVDSAVGAVIDKVDKVFVGAEGVAESGGIINLVGTYSVGV
                     LAHNARKPFYVVTESHKFVRMFPLSSDDLPMAGPPLDFTRRTDDLEDALRGPTIDYTA
                     QEYITALITDLGVLTPSAVSEELIKMWYD"
     LTR             complement(490286..490416)
                     /note="Ty1 LTR"
                     /db_xref="SGD:S000007059"
     LTR             490464..490787
                     /note="Ty1 LTR"
                     /db_xref="SGD:S000007062"
     gene            490968..491040
                     /locus_tag="tR(ACG)K"
                     /db_xref="GeneID:853897"
     tRNA            490968..491040
                     /locus_tag="tR(ACG)K"
                     /product="tRNA-Arg"
                     /note="Arginine tRNA (tRNA-Arg), predicted by tRNAscan-SE
                     analysis; one of 6 nuclear tRNA genes containing the
                     tDNA-anticodon ACG (converted to ICG in the mature tRNA),
                     decodes CGU, CGC, and probably CGA codons into arginine,
                     one of 19 nuclear tRNAs for arginine"
                     /db_xref="SGD:S000006703"
                     /db_xref="GeneID:853897"
     gene            <491364..>493661
                     /gene="BCH2"
                     /locus_tag="YKR027W"
                     /gene_synonym="FMP50"
                     /db_xref="GeneID:853898"
     mRNA            <491364..>493661
                     /gene="BCH2"
                     /locus_tag="YKR027W"
                     /gene_synonym="FMP50"
                     /product="Bch2p"
                     /transcript_id="NM_001179817.3"
                     /db_xref="GI:398365028"
                     /db_xref="GeneID:853898"
     CDS             491364..493661
                     /gene="BCH2"
                     /locus_tag="YKR027W"
                     /gene_synonym="FMP50"
                     /note="Member of the ChAPs (Chs5p-Arf1p-binding proteins)
                     family; part of the exomer complex with Chs5p to mediate
                     export of specific cargo proteins, including Chs3p, from
                     the Golgi to the plasma membrane; BCH2 has a paralog,
                     CHS6, that arose from the whole genome duplication"
                     /codon_start=1
                     /product="Bch2p"
                     /protein_id="NP_012952.3"
                     /db_xref="GI:398365029"
                     /db_xref="SGD:S000001735"
                     /db_xref="GeneID:853898"
                     /translation="MSFLWGSTKSKKGKNKKAAGSLPSGVVPQQRVKPTRKNVPIDYP
                     RTLEKVHGESLIFRTSLLSELVSTGKSGIGPPDLIHCTELDKFHDEKIGEFFYITGID
                     ASSVSMPIAFLKLIKWNDGKKLKSASLKNDDITTYCTFNIFQKLDIRLRYESEDVYQV
                     NIVDCLNGNNEIPLSDLIWEETFVSCCIRSVIINSDFERKIPGLVELPFVFENRCASD
                     YKRVIDSLCKFLPRFLECGWDSTKSVYATILNNYLTESLLVFLSITPEFITDYAIQVL
                     DNLMTNDPSNSRYYAIVIISIMERSNDRDVEMIKRIHEILDLLLPVLYGLPSDEPYIS
                     DLINCITDVLSIQARFLLNNNDYELSLSISTLATNLSSDNFESWYLLSKGYIFSQQYD
                     KALLSINSMPCLAEYDIVKQAQINAFKFYMNYYKAPLCHSREHCTMTSHELNHLMNIM
                     HYENELELKTIIFGRTVMPNESKYGCIEEIWNKSCLELGPICGPQSDNLINFVSQQEV
                     NTVGDMLLLKRSKETRQESWFIKQVRLLLMELVARIGWNALLQLRSDVFVMESKFKMI
                     ESSDKLSTELRQKRLCQRWFDAMFLDVYEDLSISTSSQENKATAKYSGLEWELLGLTL
                     LRVSDLPDAVACLRTSILARFDPISCHHLLNFYLTMDFNDEFMRRFDVDIILDLLVKL
                     ISFRIRFYDRFQIFSLQVLRKLEGQLGSEIIKNKIINSPYGQAGITSVIDYMLECLSK
                     NRNEACLAYERPLPDLPSTIKPLAD"
     gene            <494257..>497358
                     /gene="SAP190"
                     /locus_tag="YKR028W"
                     /db_xref="GeneID:853899"
     mRNA            <494257..>497358
                     /gene="SAP190"
                     /locus_tag="YKR028W"
                     /product="Sap190p"
                     /transcript_id="NM_001179818.2"
                     /db_xref="GI:330443661"
                     /db_xref="GeneID:853899"
     CDS             494257..497358
                     /gene="SAP190"
                     /locus_tag="YKR028W"
                     /note="Protein that forms a complex with the Sit4p protein
                     phosphatase; required for Sit4p function; member of a
                     family of similar proteins including Sap4p, Sap155p, and
                     Sap185p; SAP190 has a paralog, SAP185, that arose from the
                     whole genome duplication"
                     /codon_start=1
                     /product="Sap190p"
                     /protein_id="NP_012953.2"
                     /db_xref="GI:330443662"
                     /db_xref="SGD:S000001736"
                     /db_xref="GeneID:853899"
                     /translation="MSGSFWKFGQDYSIESPVSKILNSAFIKINKDQDDDVPTGTCEE
                     NIADDEDNSSHDYAASEDNVVNENEEKEEENTLPTTESEYENYRPNLDVLDDLLDDDE
                     LYTELMCSNFKLLIFLKYPDVLSKLIEYVTNEKILDEETDSAKKPEIIEGVNDHPILI
                     ERDRKDKKEDAEEGGDSEETTNDSDHDSGDERSVDSEETSITLPPESEEQVETRRARI
                     AAEILSADVWPISAAIMQNKDLLGRLWSILDHPAPLPIPASTYFMKINERLLDMDITG
                     MLEFILSRDSLVARFLTHVDNPSLMDFLLKVISTDKPDSPTGVIKILKSQELIPKLLD
                     HLNPEYGISTQSAAGDFIKAFVTLSTNSSNELASGIGPNELTRQLVSEEMIEKLIKIM
                     LKGGTSLSNGVGIIIELIRKNNSDYDFIQLVYTTLESHPPTDRDPIHLIHLVKLFAKH
                     MPDFADMLDKTKLPLMEMPFGNIEPLGFERFKICELIAELLHCSNMTLLNEPNGEMIA
                     QERDIERAKELETSTEKENITAIVDNKSSYYDKDCVEKDITENLGALQINNQGSEEDE
                     LNDTGVSSVKLDVKSDAKVVEGLENDASGVELYDETLSDTESVRECLREKPLVGDRLK
                     IALEDTKILISILDMFTEFPWNNFLHNVIFDIAQQIFNGPLKTGYNRFLLKDYLVDAY
                     LTKKIVDADKACQDYEKKTGLRYGYMGHLTLVAEEISKFKEYIDEMKLTFCNTAVSDR
                     LEEPFWKEYSETILADTREKYNTVLGDFGNDQESDDDVIRNSDSEDIIGDTEGNENYG
                     NGENDELLSNGHDSGNMDLYYNFNNNENEENEEDYAEYSDVDNKNYYNNVETNDDDYD
                     SDDGKSKSAESEFTDKISEHRDGNSLYNEDNDENGSDKWTSGTSLFPPDHFPSRSQPS
                     DPKLQDQNIFHHQFDFEGVGDDDDYMDPNDDGQSYARPGNPLYTTPKTPPRPKTILFN
                     SLSALDNNGEDEEVALGTSVDDRMDNEISSDEEDSEDEDEENDMGNEEGYSLYRSRSK
                     EAF"
     gene            complement(<497578..>499833)
                     /gene="SET3"
                     /locus_tag="YKR029C"
                     /db_xref="GeneID:853900"
     mRNA            complement(<497578..>499833)
                     /gene="SET3"
                     /locus_tag="YKR029C"
                     /product="histone-binding protein SET3"
                     /transcript_id="NM_001179819.3"
                     /db_xref="GI:398365040"
                     /db_xref="GeneID:853900"
     CDS             complement(497578..499833)
                     /gene="SET3"
                     /locus_tag="YKR029C"
                     /note="Defining member of the SET3 histone deacetylase
                     complex; which is a meiosis-specific repressor of
                     sporulation genes; necessary for efficient transcription
                     by RNAPII; one of two yeast proteins that contains both
                     SET and PHD domains; SET3 has a paralog, SET4, that arose
                     from the whole genome duplication"
                     /codon_start=1
                     /product="histone-binding protein SET3"
                     /protein_id="NP_012954.3"
                     /db_xref="GI:398365041"
                     /db_xref="SGD:S000001737"
                     /db_xref="GeneID:853900"
                     /translation="MSVPNSKEQSLLDDASTLLLFSKGKKRAEEASKIGSKTDTIEHD
                     ESHEREKKGAIEMAAAALATASTVSLPLKKATEQSAAEAATSTAAKEETENQPQKQPQ
                     WPVPDSYIVDPDAGIITCICDLNDDDGFTIQCDHCNRWQHAICYGIKDIGMAPDDYLC
                     NSCDPREVDINLARKIQQERINVKTVEPSSSNNSASNKNNGRDRASSTTISDVGDSFS
                     TDQDNTNHRDKRRKRNPSNNSIDSKNESASVNSSDGLTSMPKKKEHFLSAKDAYGAIY
                     LPLKDNVFKSDLIEPFLNKHMDDNWVIQYPHKTFKSVSIEVKPYADIAYSRTYPGFTK
                     LGVYLKKDCIKGDFIQEILGELDFYKNYLTDPRNHYRIWGTAKRRVIFHSHWPIYIDA
                     RLSGNSTRYLRRSCQPNVELVTIKLQDTDNRNDKSSGRKSSRIKFVLRALRDISEDEE
                     LYIKWQWDSKHPILKLIKGMTIDSLDDLERYGLINSVETILSNGECGCGNNSKDCYLL
                     KVKRYAQSLYKSVKSRGKMNNRYKLNEILNQYNCKKRREPPILHRLEEKAQNTIERAP
                     ILLNNFYRQKFLNRNNGPKIPQKNTIDSTNNPDDIAKPFKFALFAQHSSNISVPKKNE
                     TSEKPLIITKSTDYDESHITNIEELPIPVLLPINKTSRQTANDVEESQSKNEHKLSRT
                     PSLSNFNKELSKEAQHSQAKTKEIMTEASVNSRRESTPESIMHLSDFSSSQLHSKKKL
                     SFADYRKKLLK"
     gene            <500282..>501103
                     /gene="GMH1"
                     /locus_tag="YKR030W"
                     /gene_synonym="MSG1"
                     /db_xref="GeneID:853901"
     mRNA            <500282..>501103
                     /gene="GMH1"
                     /locus_tag="YKR030W"
                     /gene_synonym="MSG1"
                     /product="Gmh1p"
                     /transcript_id="NM_001179820.1"
                     /db_xref="GI:296146405"
                     /db_xref="GeneID:853901"
     CDS             500282..501103
                     /gene="GMH1"
                     /locus_tag="YKR030W"
                     /gene_synonym="MSG1"
                     /note="Golgi membrane hypothetical protein; interacts with
                     Gea1p and Gea2p; required for localization of Gea2p;
                     computational analysis suggests a possible role in either
                     cell wall synthesis or protein-vacuolar targeting"
                     /codon_start=1
                     /product="Gmh1p"
                     /protein_id="NP_012955.1"
                     /db_xref="GI:6322882"
                     /db_xref="SGD:S000001738"
                     /db_xref="GeneID:853901"
                     /translation="MSYLPTYSNDLPAGPQGQRRRNNGNENDARQGYGQQSVPMVIRR
                     LFKTPKNLDLETASWEMFHLIFHPRKAYRSIYYQRQTKNQWARDDPSFFIFQIALISL
                     SSIIWSIYNSGFNNDSDMGALSIIGHFFKSLVMMVILDFFIFGFIMATIFYLLLNRSH
                     FKFKSSQNSVVEWAYCFDVHCNSFLIILLCLYFIQFLLLPIINLQNWISLLIGNSLYC
                     FAIGHYFILTFYGYNQLPFLKNLNFILLPTLGLSIIYLISLFGIDLSKKLSFYNY"
     gene            complement(<501344..>506395)
                     /gene="SPO14"
                     /locus_tag="YKR031C"
                     /gene_synonym="PLD1"
                     /db_xref="GeneID:853902"
     mRNA            complement(<501344..>506395)
                     /gene="SPO14"
                     /locus_tag="YKR031C"
                     /gene_synonym="PLD1"
                     /product="phospholipase D"
                     /transcript_id="NM_001179821.3"
                     /db_xref="GI:398365056"
                     /db_xref="GeneID:853902"
     CDS             complement(501344..506395)
                     /gene="SPO14"
                     /locus_tag="YKR031C"
                     /gene_synonym="PLD1"
                     /EC_number="3.1.4.4"
                     /note="Phospholipase D; catalyzes the hydrolysis of
                     phosphatidylcholine, producing choline and phosphatidic
                     acid; involved in Sec14p-independent secretion; required
                     for meiosis and spore formation; differently regulated in
                     secretion and meiosis; participates in transcription
                     initiation and/or early elongation of specific genes;
                     interacts with 'foot domain' of RNA polymerase II;
                     deletion results in abnormal CTD-Ser5 phosphorylation of
                     RNA polymerase II at specific promoter regions"
                     /codon_start=1
                     /product="phospholipase D"
                     /protein_id="NP_012956.3"
                     /db_xref="GI:398365057"
                     /db_xref="SGD:S000001739"
                     /db_xref="GeneID:853902"
                     /translation="MSNVSTASGTHFAPPQADRSVTEEVDRVNSRPDELENQEVLRQL
                     PENGNLTSSLQREKRRTPNGKEAERKHALPKSFVDRNLSDVSPNHSLDHIMHSNEHDP
                     RRGSDEENMHRLYNNLHSSNNNVHSKRNSKREEERAPQRRSSSVAYTQQQFNGWKKEF
                     GHAFKKISAIGRLKSSVNSPTPAGSGHRHNQHQHQQVNEEDLYTQRLASDLLDSLLAG
                     CPASLFASTQFLRDEHGKRRAPLLLAKLDVRVSPLKNDNNILDITNSNHNHRGNNNNN
                     TGENSDRRPSIPRSSSIISISSNVAEFMYSRNENSLFRIHLEYGIDEDRLKWSIIRSY
                     KDIKSLHHKLKIVAFQQLTISKLYSDNNRYHSLQLPHFPHYKEMVKERNVMEKKAENK
                     PSSAASAPHTSENNNNDNGSNITSLETLSSSEISEFNIDNVKMKHLQDLIDEPDDFSQ
                     PIHLRLERYLRLLNIALCLRPHANRLFEFYELSPLGNLLSRESGFQGKQGYLVIRSTA
                     KAQGWRVSHFGKHAFKDMIDRHTTKWFLVRNSYLTYVSDLSSTTPLDVFLIDWKFKVR
                     FSGNKNNILDNENEINWIIHDPNLEINDELEEFGIENDANNILDKNGKSKTHQKKSNI
                     SSKLLLLTLENSERKLKIICKSESSLKQWMSSIIKMSTSTPWSKPNRFGSFAPVRTNS
                     FCKFLVDGRDYFWSLSEALLMAKDVIYIHDWWLSPELYLRRPVKGNQGFRIDRMLKSC
                     AEKGIKIFIVIYRNVGNIVGTDSLWTKHSMLNLHPNIHIIRSPNQWLQNTYFWAHHEK
                     FVVIDETFAFIGGTDLCYGRYDTFEHVLRDDAESLLDQNFPGKDYSNARIADFHDLDK
                     PFESMYDRKVIPRMPWHDVQMMTLGEPARDLARHFVQRWNYLLRAKRPSRLTPLLTPP
                     SDLTAEELKSLPMFEILREKSTCETQILRSAGNWSLGLKETECSIQNAYLKLIEQSEH
                     FIYIENQFFITSTVWNGTCVLNKIGDALVDRIVKANQEKKPWKAFILIPLMPGFDSPV
                     DTAEASSLRLIMQFQYQSISRGEHSTFSKLKKLNIDPAQYIQFFSLRKWSTFAPNERL
                     ITEQLYVHAKILIADDRRCIIGSANINERSQLGNRDSEVAILIRDTDLIKTKMNGDDY
                     YAGKFPWELRQRLMREHLGCDVDLVEFVEKKFERFEKFAAKNYEKLHTLSKEGDSGNN
                     WSDREMIDSAMIELGYREIFGCKFSPQWKSGHGNSVDDGSTQCGINEKEVGREDENVY
                     EKFFNSVDYGKSSRKRTPLPKHNFASLGLTFNHRAGIENVGIRDHKVLSTDPRLRKND
                     EHKKEVDGYGPDCWKKESNKKFKADATEQLKEWALNSLASKVLDDKEMIKSEIPEGFS
                     NYLPNEKDLEMYLTDKTVTNRNKWSMLKRICYLQYLSHKLDERKTQRLKKIKDMRRHL
                     SSSTESTRNGSNSLPLNEKSNEGESTNVDQDIEGDEYHRLHEDILKNQELDDGSLDDL
                     LSQIIPKITNFNSGEIDDAKKEELLKLNFIDPYSFEDPLISSFSEGLWFTIALRNTLL
                     YKLVFHCQPDNAVQNWKEYGEFTELEQEFQINQEKLIDLEAENINSTTTNVVDKDREK
                     EKMRKAAELRMKLSGSLLYGFNQKVFDKHTAQRILERIHGHLVIFPTEWLAKEVESRN
                     WIFNSDRLSPMEIYN"
     gene            <506898..>507707
                     /gene="DAL80"
                     /locus_tag="YKR034W"
                     /gene_synonym="UGA43"
                     /db_xref="GeneID:853904"
     mRNA            <506898..>507707
                     /gene="DAL80"
                     /locus_tag="YKR034W"
                     /gene_synonym="UGA43"
                     /product="Dal80p"
                     /transcript_id="NM_001179824.1"
                     /db_xref="GI:296146407"
                     /db_xref="GeneID:853904"
     CDS             506898..507707
                     /gene="DAL80"
                     /locus_tag="YKR034W"
                     /gene_synonym="UGA43"
                     /note="Negative regulator of genes in multiple nitrogen
                     degradation pathways; expression is regulated by nitrogen
                     levels and by Gln3p; member of the GATA-binding family,
                     forms homodimers and heterodimers with Gzf3p; DAL80 has a
                     paralog, GZF3, that arose from the whole genome
                     duplication"
                     /codon_start=1
                     /product="Dal80p"
                     /protein_id="NP_012959.1"
                     /db_xref="GI:6322885"
                     /db_xref="SGD:S000001742"
                     /db_xref="GeneID:853904"
                     /translation="MVLSDSLKLPSPTLSAAAGVDDCDGEDHPTCQNCFTVKTPLWRR
                     DEHGTVLCNACGLFLKLHGEPRPISLKTDTIKSRNRKKLNNNNVNTNANTHSNDPNKI
                     FKRKKRLLTTGGGSLPTNNPKVSILEKFMVSGSIKPLLKPKETVPNTKECSTQRGKFS
                     LDPCEPSGKNYLYQINGSDIYTSNIELTRLPNLSTLLEPSPFSDSAVPEIELTWKLHN
                     EEEVIKLKTKISELELVTDLYKKHIFQLNEKCKQLEVELHSRASVQSHPQH"
     gene            <507939..>508553
                     /gene="DID2"
                     /locus_tag="YKR035W-A"
                     /gene_synonym="CHM1; FTI1; VPL30; VPS46"
                     /db_xref="GeneID:853906"
     mRNA            <507939..>508553
                     /gene="DID2"
                     /locus_tag="YKR035W-A"
                     /gene_synonym="CHM1; FTI1; VPL30; VPS46"
                     /product="Did2p"
                     /transcript_id="NM_001184309.3"
                     /db_xref="GI:398365064"
                     /db_xref="GeneID:853906"
     CDS             507939..508553
                     /gene="DID2"
                     /locus_tag="YKR035W-A"
                     /gene_synonym="CHM1; FTI1; VPL30; VPS46"
                     /note="Class E protein of the vacuolar protein-sorting
                     (Vps) pathway; binds Vps4p and directs it to dissociate
                     ESCRT-III complexes; forms a functional and physical
                     complex with Ist1p; human ortholog may be altered in
                     breast tumors"
                     /codon_start=1
                     /product="Did2p"
                     /protein_id="NP_012961.3"
                     /db_xref="GI:398365065"
                     /db_xref="SGD:S000006435"
                     /db_xref="GeneID:853906"
                     /translation="MSRNSAAGLENTLFQLKFTSKQLQKQANKASKEEKQETNKLKRA
                     LNENEDISRIYASNAIRKKNERLQLLKLASRVDSVASRVQTAVTMRQVSASMGQVCKG
                     MDKALQNMNLQQITMIMDKFEQQFEDLDTSVNVYEDMGVNSDAMLVDNDKVDELMSKV
                     ADENGMELKQSAKLDNVPEIKAKEVNVDDEKEDKLAQRLRALRG"
     gene            complement(<508702..>510633)
                     /gene="CAF4"
                     /locus_tag="YKR036C"
                     /db_xref="GeneID:853908"
     mRNA            complement(<508702..>510633)
                     /gene="CAF4"
                     /locus_tag="YKR036C"
                     /product="Caf4p"
                     /transcript_id="NM_001179826.2"
                     /db_xref="GI:330443663"
                     /db_xref="GeneID:853908"
     CDS             complement(508702..510633)
                     /gene="CAF4"
                     /locus_tag="YKR036C"
                     /note="WD40 repeat-containing protein associated with the
                     CCR4-NOT complex; interacts in a Ccr4p-dependent manner
                     with Ssn2p; also interacts with Fis1p, Mdv1p and Dnm1p and
                     plays a role in mitochondrial fission; CAF4 has a paralog,
                     MDV1, that arose from the whole genome duplication"
                     /codon_start=1
                     /product="Caf4p"
                     /protein_id="NP_012962.3"
                     /db_xref="GI:330443664"
                     /db_xref="SGD:S000001744"
                     /db_xref="GeneID:853908"
                     /translation="MGSGDTRGESSLVAKPIEIILNKLPHAILAQQQFQKYITSPIYR
                     YLSKLLLFREVAWPESTKDTQKGQVGIFSFQNNYADSATTFRILAHLDEQRYPLPNGA
                     AEKNLPSLFEGFKATVSIIQQRLLLDNVDGATNSDKEKYVQLPDINTGFVNKTYSRID
                     LTHLLEDVETNVENLSINKTLEMDELTRLDSMINELESRKLKILERVKHIDSKSTNLE
                     NDVTLIKDRINFIEEYNLEADREQSLRKQMEEERSSEASSFTQNEEAISSLCDVESKD
                     TRLKDFYKMPHEKSHDKNRQIISETYSRNTTAFRMTIPHGEHGNSITALDFDTPWGTL
                     CSSSYQDRIVKVWDLNHGIQVGELPGHLATVNCMQIDKKNYNMLITGSKDATLKLWDL
                     NLSREIYLDHSPLKEKTEEIVTPCIHNFELHKDEITALSFDSEALVSGSRDKKIFHWD
                     LTTGKCIQQLDLIFTPTHSDIKMPARSLNNGACLLGTEAPMIGALQCYNSALATGTKD
                     GIVRLWDLRVGKPVRLLEGHTDGITSLKFDSEKLVTGSMDNSVRIWDLRTSSILDVIA
                     YDLPVSSLDFDGKLITVGANEGGVNVFNMERDEHWMTPEPPHSLDGDELSRRIAIVKY
                     KDGFLINGHNDGDINVWTL"
     gene            complement(<510910..>511797)
                     /gene="SPC34"
                     /locus_tag="YKR037C"
                     /db_xref="GeneID:853909"
     mRNA            complement(<510910..>511797)
                     /gene="SPC34"
                     /locus_tag="YKR037C"
                     /product="Spc34p"
                     /transcript_id="NM_001179827.3"
                     /db_xref="GI:398365080"
                     /db_xref="GeneID:853909"
     CDS             complement(510910..511797)
                     /gene="SPC34"
                     /locus_tag="YKR037C"
                     /note="Essential subunit of the Dam1 complex (aka DASH
                     complex); complex couples kinetochores to the force
                     produced by MT depolymerization thereby aiding in
                     chromosome segregation; also localized to nuclear side of
                     spindle pole body"
                     /codon_start=1
                     /product="Spc34p"
                     /protein_id="NP_012963.3"
                     /db_xref="GI:398365081"
                     /db_xref="SGD:S000001745"
                     /db_xref="GeneID:853909"
                     /translation="MGESLDRCIDDINRAVDSMSTLYFKPPGIFHNAILQGASNKASI
                     RKDITRLIKDCNHDEAYLLFKVNPEKQSVSRRDGKEGVFDYVIKRDTDMKRNRRLGRP
                     GEKPIIHVPKEVYLNKDRLDLNNKRRRTATTSGGGLNGFIFDTDLIGSSVISNSSSGT
                     FKALSAVFKDDPQIQRLLYALENGSVLMEEESNNQRRKTIFVEDFPTDLILKVMAEVT
                     DLWPLTEFKQDYDQLYHNYEQLSSKLRFIKKEVLLQDDRLKTMSQYHPSSSHDVAKII
                     RKEKDEIRRLEMEIANLQE"
     gene            complement(<511999..>513159)
                     /gene="KAE1"
                     /locus_tag="YKR038C"
                     /db_xref="GeneID:853910"
     mRNA            complement(<511999..>513159)
                     /gene="KAE1"
                     /locus_tag="YKR038C"
                     /product="Kae1p"
                     /transcript_id="NM_001179828.1"
                     /db_xref="GI:296146411"
                     /db_xref="GeneID:853910"
     CDS             complement(511999..513159)
                     /gene="KAE1"
                     /locus_tag="YKR038C"
                     /EC_number="2.6.99.4"
                     /note="Highly conserved ATPase of HSP70/DnaK family;
                     essential functional component of the EKC/KEOPS complex,
                     with Bud32p, Cgi121p, Pcc1p, and Gon7p; EKC/KEOPS complex
                     is required for t6A tRNA modification and telomeric TG1-3
                     recombination; may have role in transcription"
                     /codon_start=1
                     /product="Kae1p"
                     /protein_id="NP_012964.2"
                     /db_xref="GI:37362674"
                     /db_xref="SGD:S000001746"
                     /db_xref="GeneID:853910"
                     /translation="MVNLNTIPPKNGRDYYIALGLEGSANKLGVGIVKHPLLPKHANS
                     DLSYDCEAEMLSNIRDTYVTPPGEGFLPRDTARHHRNWCIRLIKQALAEADIKSPTLD
                     IDVICFTKGPGMGAPLHSVVIAARTCSLLWDVPLVGVNHCIGHIEMGREITKAQNPVV
                     LYVSGGNTQVIAYSEKRYRIFGETLDIAIGNCLDRFARTLKIPNEPSPGYNIEQLAKK
                     APHKENLVELPYTVKGMDLSMSGILASIDLLAKDLFKGNKKNKILFDKTTGEQKVTVE
                     DLCYSLQENLFAMLVEITERAMAHVNSNQVLIVGGVGCNVRLQEMMAQMCKDRANGQV
                     HATDNRFCIDNGVMIAQAGLLEYRMGGIVKDFSETVVTQKFRTDEVYAAWRD"
     gene            complement(513332..513403)
                     /locus_tag="tD(GUC)K"
                     /db_xref="GeneID:853911"
     tRNA            complement(513332..513403)
                     /locus_tag="tD(GUC)K"
                     /product="tRNA-Asp"
                     /note="Aspartate tRNA (tRNA-Asp), predicted by tRNAscan-SE
                     analysis"
                     /db_xref="SGD:S000006540"
                     /db_xref="GeneID:853911"
     LTR             complement(513532..513846)
                     /note="Ty1 LTR"
                     /db_xref="SGD:S000007060"
     gene            <515063..>516871
                     /gene="GAP1"
                     /locus_tag="YKR039W"
                     /db_xref="GeneID:853912"
     mRNA            <515063..>516871
                     /gene="GAP1"
                     /locus_tag="YKR039W"
                     /product="amino acid permease GAP1"
                     /transcript_id="NM_001179829.3"
                     /db_xref="GI:398365092"
                     /db_xref="GeneID:853912"
     CDS             515063..516871
                     /gene="GAP1"
                     /locus_tag="YKR039W"
                     /note="General amino acid permease; Gap1p senses the
                     presence of amino acid substrates to regulate localization
                     to the plasma membrane when needed; essential for invasive
                     growth"
                     /codon_start=1
                     /product="amino acid permease GAP1"
                     /protein_id="NP_012965.3"
                     /db_xref="GI:398365093"
                     /db_xref="SGD:S000001747"
                     /db_xref="GeneID:853912"
                     /translation="MSNTSSYEKNNPDNLKHNGITIDSEFLTQEPITIPSNGSAVSID
                     ETGSGSKWQDFKDSFKRVKPIEVDPNLSEAEKVAIITAQTPLKHHLKNRHLQMIAIGG
                     AIGTGLLVGSGTALRTGGPASLLIGWGSTGTMIYAMVMALGELAVIFPISGGFTTYAT
                     RFIDESFGYANNFNYMLQWLVVLPLEIVSASITVNFWGTDPKYRDGFVALFWLAIVII
                     NMFGVKGYGEAEFVFSFIKVITVVGFIILGIILNCGGGPTGGYIGGKYWHDPGAFAGD
                     TPGAKFKGVCSVFVTAAFSFAGSELVGLAASESVEPRKSVPKAAKQVFWRITLFYILS
                     LLMIGLLVPYNDKSLIGASSVDAAASPFVIAIKTHGIKGLPSVVNVVILIAVLSVGNS
                     AIYACSRTMVALAEQRFLPEIFSYVDRKGRPLVGIAVTSAFGLIAFVAASKKEGEVFN
                     WLLALSGLSSLFTWGGICICHIRFRKALAAQGRGLDELSFKSPTGVWGSYWGLFMVII
                     MFIAQFYVAVFPVGDSPSAEGFFEAYLSFPLVMVMYIGHKIYKRNWKLFIPAEKMDID
                     TGRREVDLDLLKQEIAEEKAIMATKPRWYRIWNFWC"
     rep_origin      517017..517265
                     /note="ARS1116;
                     Autonomously Replicating Sequence"
                     /db_xref="SGD:S000118407"
     LTR             complement(517453..517784)
                     /note="Ty1 LTR"
                     /db_xref="SGD:S000007061"
     gene            517988..518060
                     /locus_tag="tA(AGC)K2"
                     /db_xref="GeneID:853913"
     tRNA            517988..518060
                     /locus_tag="tA(AGC)K2"
                     /product="tRNA-Ala"
                     /note="Alanine tRNA (tRNA-Ala), predicted by tRNAscan-SE
                     analysis; one of 11 nuclear tRNA genes containing the
                     tDNA-anticodon AGC (converted to IGC in the mature tRNA),
                     decodes GCU and GCC codons into alanine, one of 16 nuclear
                     tRNAs for alanine"
                     /db_xref="SGD:S000006516"
                     /db_xref="GeneID:853913"
     gene            <518198..>518950
                     /locus_tag="YKR041W"
                     /db_xref="GeneID:853914"
     mRNA            <518198..>518950
                     /locus_tag="YKR041W"
                     /product="hypothetical protein"
                     /transcript_id="NM_001179831.1"
                     /db_xref="GI:296146413"
                     /db_xref="GeneID:853914"
     CDS             518198..518950
                     /locus_tag="YKR041W"
                     /note="hypothetical protein; localizes to the mitotic
                     spindle; overexpression of YKR041W affects endocytic
                     protein trafficking"
                     /codon_start=1
                     /product="hypothetical protein"
                     /protein_id="NP_012967.1"
                     /db_xref="GI:6322893"
                     /db_xref="SGD:S000001749"
                     /db_xref="GeneID:853914"
                     /translation="MSDDDYMNSDDDNDAEKRYVRPIFVRKRRREEDYVATSKDNIHH
                     HPCDWSAKPSQRQNENEQKSTIRLVPVAMNTPKCQEKKKKRKGVGTTSHEATLFEYGE
                     SIAGYKCVTTESERDRLKRSHESESSSESEVDVFAFDQAKGISSKVEAEERYARAVRQ
                     YWRMTKDEPATLPLPGTPTLAAVSLDMIDDKSVEQFYTMSSALMDANRLDLIRRDRIR
                     WHPDKHRYHKSKVTKLFQAINGLWEQEKTEKR"
     gene            <519527..>520624
                     /gene="UTH1"
                     /locus_tag="YKR042W"
                     /db_xref="GeneID:853916"
     mRNA            <519527..>520624
                     /gene="UTH1"
                     /locus_tag="YKR042W"
                     /product="SUN family protein UTH1"
                     /transcript_id="NM_001179832.3"
                     /db_xref="GI:398365110"
                     /db_xref="GeneID:853916"
     CDS             519527..520624
                     /gene="UTH1"
                     /locus_tag="YKR042W"
                     /EC_number="3.2.1.-"
                     /note="Mitochondrial inner membrane protein; role in
                     mitophagy is disputed; implicated in cell wall biogenesis,
                     the oxidative stress response, life span during
                     starvation, and cell death; SUN family member; UTH1 has a
                     paralog, NCA3, that arose from the whole genome
                     duplication"
                     /codon_start=1
                     /product="SUN family protein UTH1"
                     /protein_id="NP_012968.4"
                     /db_xref="GI:398365111"
                     /db_xref="SGD:S000001750"
                     /db_xref="GeneID:853916"
                     /translation="MKLSALLALSASTAVLAAPAVHHSDNHHHNDKRAVVTVTQYVNA
                     DGAVVIPAATTATSAAADGKVESVAAATTTLSSTAAAATTSAAASSSSSSSSSSSSSS
                     SVGSGDFEDGTISCSDFPSGQGAVSLDWLGLGGWASIMDMNGNTATSCQDGYYCSYAC
                     SPGYAKTQWPSEQPSDGRSVGGLYCKNGKLYRSNTDTNSLCVEGQGSAQAVNKVSGSI
                     AICGTDYPGSENMVVPTVVGAGSSQPINVIKEDSYYQWQGKKTSAQYYVNNAGVSVED
                     GCIWGTEGSGVGNWAPVVLGAGYTDGITYLSIIPNPNNKEAPNFNIKIVATDGSTVNG
                     ACSYENGVYSGSGSDGCTVSVTSGSANFVFY"
     gene            complement(<520897..>521712)
                     /gene="SHB17"
                     /locus_tag="YKR043C"
                     /db_xref="GeneID:853917"
     mRNA            complement(<520897..>521712)
                     /gene="SHB17"
                     /locus_tag="YKR043C"
                     /product="Shb17p"
                     /transcript_id="NM_001179833.1"
                     /db_xref="GI:296146415"
                     /db_xref="GeneID:853917"
     CDS             complement(520897..521712)
                     /gene="SHB17"
                     /locus_tag="YKR043C"
                     /EC_number="3.1.3.37"
                     /note="Sedoheptulose bisphosphatase involved in
                     riboneogenesis; dephosphorylates sedoheptulose
                     1,7-bisphosphate, which is converted via the nonoxidative
                     pentose phosphate pathway to ribose-5-phosphate;
                     facilitates the conversion of glycolytic intermediates to
                     pentose phosphate units; also has fructose
                     1,6-bisphosphatase activity but this is probably not
                     biologically relevant, since deletion does not affect FBP
                     levels; GFP-fusion protein localizes to the cytoplasm and
                     nucleus"
                     /codon_start=1
                     /product="Shb17p"
                     /protein_id="NP_012969.1"
                     /db_xref="GI:6322896"
                     /db_xref="SGD:S000001751"
                     /db_xref="GeneID:853917"
                     /translation="MPSLTPRCIIVRHGQTEWSKSGQYTGLTDLPLTPYGEGQMLRTG
                     ESVFRNNQFLNPDNITYIFTSPRLRARQTVDLVLKPLSDEQRAKIRVVVDDDLREWEY
                     GDYEGMLTREIIELRKSRGLDKERPWNIWRDGCENGETTQQIGLRLSRAIARIQNLHR
                     KHQSEGRASDIMVFAHGHALRYFAAIWFGLGVQKKCETIEEIQNVKSYDDDTVPYVKL
                     ESYRHLVDNPCFLLDAGGIGVLSYAHHNIDEPALELAGPFVSPPEEESQHGDV"
     gene            <522015..>523346
                     /gene="UIP5"
                     /locus_tag="YKR044W"
                     /db_xref="GeneID:853918"
     mRNA            <522015..>523346
                     /gene="UIP5"
                     /locus_tag="YKR044W"
                     /product="Uip5p"
                     /transcript_id="NM_001179834.3"
                     /db_xref="GI:398365126"
                     /db_xref="GeneID:853918"
     CDS             522015..523346
                     /gene="UIP5"
                     /locus_tag="YKR044W"
                     /note="hypothetical protein that interacts with Ulp1p; a
                     Ubl (ubiquitin-like protein)-specific protease for Smt3p
                     protein conjugates"
                     /codon_start=1
                     /product="Uip5p"
                     /protein_id="NP_012970.3"
                     /db_xref="GI:398365127"
                     /db_xref="SGD:S000001752"
                     /db_xref="GeneID:853918"
                     /translation="MSRDVRAEKLAISLLILSLFLIFQLVAEIYLNNGDQYHTETSPF
                     TRGRSHVTRVPNHDASLSIPFLDKINQFWHVGGATQIRNIQSIKLTQDRDQDKHGLVL
                     SNGIGDNTINDFEIVFTFRISHDPTTQLTGDGMCFAITPENGFLTQNLQSSYAKKQYM
                     MNSQGVIADNTDLMGFPKNLPGLFIVLDTYRNQGHDHKEVPFMDVFINVAPESDWYDI
                     NSDGELSTSLRLNSRGHIKLKKNALWNRVTKLRIIYLESISFLKIDVQYAKEGNYWIE
                     LFQTTENLYLPKNMHTGQRYIGCSALNGQLTETVELLDVSTSEFHWNDMDASIEDTYD
                     YAKEAELFLEQEFGEVLDREPDEFTKWKMIKAQPNIKTGSQSAEQKTSNNPHSRLFKV
                     VLTIWHYSEILLLIMGIYLFSACIRVFQRRFKKIRSRRKRAGSHSVGLLPM"
     gene            complement(<523418..>523969)
                     /locus_tag="YKR045C"
                     /db_xref="GeneID:853919"
     mRNA            complement(<523418..>523969)
                     /locus_tag="YKR045C"
                     /product="hypothetical protein"
                     /transcript_id="NM_001179835.1"
                     /db_xref="GI:296146417"
                     /db_xref="GeneID:853919"
     CDS             complement(523418..523969)
                     /locus_tag="YKR045C"
                     /note="hypothetical protein; epitope-tagged protein
                     localizes to the cytoplasm"
                     /codon_start=1
                     /product="hypothetical protein"
                     /protein_id="NP_012971.2"
                     /db_xref="GI:37362675"
                     /db_xref="SGD:S000001753"
                     /db_xref="GeneID:853919"
                     /translation="MSNSHHTSQGRRNKLSVWVKKIINTTTTTNASVSSSKPRRGTRA
                     GPTRVKRAELDPDGTTISSSLRPLVDRNSLHSSESDDEGDRRVAWDEPPTGKVRQQQQ
                     QQQQQQNDNASVIPLVSFCSSSVKSSTFSDIHSIQSTRPTIFSNRTFETNSSVLAIPP
                     QSILDRSRTLPPSNASNTTTRRP"
     gene            complement(<524223..>525074)
                     /gene="PET10"
                     /locus_tag="YKR046C"
                     /db_xref="GeneID:853920"
     mRNA            complement(<524223..>525074)
                     /gene="PET10"
                     /locus_tag="YKR046C"
                     /product="Pet10p"
                     /transcript_id="NM_001179836.3"
                     /db_xref="GI:398365144"
                     /db_xref="GeneID:853920"
     CDS             complement(524223..525074)
                     /gene="PET10"
                     /locus_tag="YKR046C"
                     /note="hypothetical protein that localizes to lipid
                     particles; localization suggests a role in lipid
                     metabolism; expression pattern suggests a role in
                     respiratory growth; computational analysis of large-scale
                     protein-protein interaction data suggests a role in
                     ATP/ADP exchange"
                     /codon_start=1
                     /product="Pet10p"
                     /protein_id="NP_012972.3"
                     /db_xref="GI:398365145"
                     /db_xref="SGD:S000001754"
                     /db_xref="GeneID:853920"
                     /translation="MSESSISSSKPSVELPQATWSHLQRYPALSKFIKYAESLPPVER
                     LISFNLVVLGSVNQWVSESSSSPRLVKQVVAAGKEGAFKLDELVNLLVFKEGVDGLLY
                     NWKSHSNTPGIWLVWFFVDYVANISNTLLREFLIKPLHLQGSTASKEIGSSGEENKVT
                     DASSLPHVAELSSTTRGMSQEIQSKVKSNYIDPTKDLAKEKYDAIVKPTTDKLQSVYI
                     DPTKTKLNETYQRFTTVYENNLSKSESVPKAIVSTGLDLGNATIEKLKASREDQTNSK
                     PAAVSTN"
     gene            complement(<525387..>526640)
                     /gene="NAP1"
                     /locus_tag="YKR048C"
                     /db_xref="GeneID:853922"
     mRNA            complement(<525387..>526640)
                     /gene="NAP1"
                     /locus_tag="YKR048C"
                     /product="histone chaperone NAP1"
                     /transcript_id="NM_001179838.1"
                     /db_xref="GI:296146419"
                     /db_xref="GeneID:853922"
     CDS             complement(525387..526640)
                     /gene="NAP1"
                     /locus_tag="YKR048C"
                     /note="Histone chaperone; involved in histone exchange by
                     removing and replacing histone H2A-H2B dimers or histone
                     variant dimers from assembled nucleosomes; involved in the
                     transport of H2A and H2B histones to the nucleus; required
                     for the regulation of microtubule dynamics during mitosis;
                     interacts with mitotic cyclin Clb2p; controls bud
                     morphogenesis; phosphorylated by CK2; protein abundance
                     increases in response to DNA replication stress"
                     /codon_start=1
                     /product="histone chaperone NAP1"
                     /protein_id="NP_012974.1"
                     /db_xref="GI:6322901"
                     /db_xref="SGD:S000001756"
                     /db_xref="GeneID:853922"
                     /translation="MSDPIRTKPKSSMQIDNAPTPHNTPASVLNPSYLKNGNPVRAQA
                     QEQDDKIGTINEEDILANQPLLLQSIQDRLGSLVGQDSGYVGGLPKNVKEKLLSLKTL
                     QSELFEVEKEFQVEMFELENKFLQKYKPIWEQRSRIISGQEQPKPEQIAKGQEIVESL
                     NETELLVDEEEKAQNDSEEEQVKGIPSFWLTALENLPIVCDTITDRDAEVLEYLQDIG
                     LEYLTDGRPGFKLLFRFDSSANPFFTNDILCKTYFYQKELGYSGDFIYDHAEGCEISW
                     KDNAHNVTVDLEMRKQRNKTTKQVRTIEKITPIESFFNFFDPPKIQNEDQDEELEEDL
                     EERLALDYSIGEQLKDKLIPRAVDWFTGAALEFEFEEDEEEADEDEDEEEDDDHGLED
                     DDGESAEEQDDFAGRPEQAPECKQS"
     gene            complement(<526830..>527231)
                     /gene="FMP46"
                     /locus_tag="YKR049C"
                     /db_xref="GeneID:853923"
     mRNA            complement(<526830..>527231)
                     /gene="FMP46"
                     /locus_tag="YKR049C"
                     /product="Fmp46p"
                     /transcript_id="NM_001179839.3"
                     /db_xref="GI:398365162"
                     /db_xref="GeneID:853923"
     CDS             complement(526830..527231)
                     /gene="FMP46"
                     /locus_tag="YKR049C"
                     /EC_number="1.-.-.-"
                     /note="Putative redox protein containing a thioredoxin
                     fold; the authentic, non-tagged protein is detected in
                     highly purified mitochondria in high-throughput studies"
                     /codon_start=1
                     /product="Fmp46p"
                     /protein_id="NP_012975.3"
                     /db_xref="GI:398365163"
                     /db_xref="SGD:S000001757"
                     /db_xref="GeneID:853923"
                     /translation="MSFWKTLQRQPRTISLFTNDIASNIKSQKCLQLLKGDVSHRFDV
                     EIANRFPTWDQLQYMRTSCPQGPVSLQRQIPKLDSVLKYKHTDPTFGMDLQKCVQRGL
                     WNPKEALWVDWENKLVGNEPADIDKYIIQRK"
     gene            <527815..>530484
                     /gene="TRK2"
                     /locus_tag="YKR050W"
                     /gene_synonym="RPD2"
                     /db_xref="GeneID:853924"
     mRNA            <527815..>530484
                     /gene="TRK2"
                     /locus_tag="YKR050W"
                     /gene_synonym="RPD2"
                     /product="Trk2p"
                     /transcript_id="NM_001179840.1"
                     /db_xref="GI:296146421"
                     /db_xref="GeneID:853924"
     CDS             527815..530484
                     /gene="TRK2"
                     /locus_tag="YKR050W"
                     /gene_synonym="RPD2"
                     /note="Component of the Trk1p-Trk2p potassium transport
                     system; contributes to K(+) supply and maintenance of
                     plasma-membrane potential; TRK2 has a paralog, TRK1, that
                     arose from the whole genome duplication"
                     /codon_start=1
                     /product="Trk2p"
                     /protein_id="NP_012976.1"
                     /db_xref="GI:6322903"
                     /db_xref="SGD:S000001758"
                     /db_xref="GeneID:853924"
                     /translation="MPTAKRTSSRASLALPFQLRLVHKKSWGHRLRDFISGFLKSCRP
                     IAKYVFPNFIVVHYIYLITLSIIGSILLYPCKNTAFIDVLFLAAGASTQGGLATKSTN
                     DFNLYQQIVVYVITLLSTPILIHGFLAFVRLYWFERYFDNIRDISKQNFKLRRTMTLQ
                     QRELSGSSGNAARSRSFKDNLFRGKFVSREDPRQSASDVPMDSPDTSALSSISPLNVS
                     SSKEESSDTQSSPPNFSSKRQPSDVDPRDIYKSIMMLQKQQEKSNANSTDSFSSETNG
                     PAFIVQERHERRAPHCSLKRHSVLPSSQELNKLAQTKSFQKLLGLRRDEGDHDYFDGA
                     PHKYMVTKKKKISRTQSCNIPTYTASPSPKTSGQVVENHRNLAKSAPSSFVDEEMSFS
                     PQESLNLQFQAHPPKPKRREGDIGHPFTRTMSTNYLSWQPTFGRNSVFIGLTKQQKEE
                     LGGVEYRALRLLCCILMVYYIGFNILAFVTIVPWACTRHHYSEIIRRNGVSPTWWGFF
                     TAMSAFSNLGLSLTADSMVSFDTAPYPLIFMMFFIIIGNTGFPIMLRFIIWIMFKTSR
                     DLSQFKESLGFLLDHPRRCFTLLFPSGPTWWLFTTLVVLNATDWILFIILDFNSAVVR
                     QVAKGYRALMGLFQSVCTRTAGFNVVDLSKLHPSIQVSYMLMMYVSVLPLAISIRRTN
                     VYEEQSLGLYDSGQDDENITHEDDIKETDHDGESEERDTVSTKSKPKKQSPKSFVGAH
                     LRRQLSFDLWYLFLGLFIICICEGRKIEDVNKPDFNVFAILFEVVSAYGTVGLSLGYP
                     NTNTSLSAQFTVLSKLVIIAMLIRGRNRGLPYTLDRAIMLPSDKLEQIDRLQDMKAKG
                     KLLAKVGEDPMTTYVKKRSHKLKKIATKFWGKH"
     gene            <530946..>532202
                     /locus_tag="YKR051W"
                     /db_xref="GeneID:853925"
     mRNA            <530946..>532202
                     /locus_tag="YKR051W"
                     /product="hypothetical protein"
                     /transcript_id="NM_001179841.3"
                     /db_xref="GI:398365172"
                     /db_xref="GeneID:853925"
     CDS             530946..532202
                     /locus_tag="YKR051W"
                     /codon_start=1
                     /product="hypothetical protein"
                     /protein_id="NP_012977.3"
                     /db_xref="GI:398365173"
                     /db_xref="SGD:S000001759"
                     /db_xref="GeneID:853925"
                     /translation="MENKLLCWWLYWPCVYSSIIATIISFYTITRHLLNYRKPYEQRL
                     SIRILLLVPIFSVSCASGIIKPEAAQFYVDPIREFYEAFVIYTFFTFLTLLLGGERNI
                     ITVLSLNHAPTRHPIPLIGKICKPIDLSDPFDFLFVKKGILQYVWFKPFYCFGTLICS
                     AWKLPKFEIFLNVFYNISVTWSLYSLALFWKCLYPELTPYKPWLKFLCVKLIIFASYW
                     QSIIIQGLVVTGKLGTGNQDRTSGYVYKNGLLCIEMVPFAILHAVAFPWNKYTAFSIP
                     YGARMKFIYALKDFLGCGDLIWDFKQTLFAGPLYYNYRNFDPEAMDLLSTRQQSGATM
                     ERLKHGLRFTDNGRNSYWVAYGSIDNNLVPESIEESWEDDIAGQRTFPEDPNYPVVHD
                     YTMGHRYSRSMNDLRRDVQSRSSMAC"
     gene            complement(<532550..>533464)
                     /gene="MRS4"
                     /locus_tag="YKR052C"
                     /db_xref="GeneID:853926"
     mRNA            complement(<532550..>533464)
                     /gene="MRS4"
                     /locus_tag="YKR052C"
                     /product="Mrs4p"
                     /transcript_id="NM_001179842.1"
                     /db_xref="GI:296146423"
                     /db_xref="GeneID:853926"
     CDS             complement(532550..533464)
                     /gene="MRS4"
                     /locus_tag="YKR052C"
                     /note="Iron transporter of the mitochondrial carrier
                     family; mediates Fe2+ transport across the inner
                     mitochondrial membrane; active under low-iron conditions;
                     may transport other cations; protein abundance increases
                     in response to DNA replication stress; MRS4 has a paralog,
                     MRS3, that arose from the whole genome duplication"
                     /codon_start=1
                     /product="Mrs4p"
                     /protein_id="NP_012978.1"
                     /db_xref="GI:6322905"
                     /db_xref="SGD:S000001760"
                     /db_xref="GeneID:853926"
                     /translation="MNTSELSIAEEIDYEALPSHAPLHSQLLAGAFAGIMEHSLMFPI
                     DALKTRVQAAGLNKAASTGMISQISKISTMEGSMALWKGVQSVILGAGPAHAVYFGTY
                     EFCKARLISPEDMQTHQPMKTALSGTIATIAADALMNPFDTVKQRLQLDTNLRVWNVT
                     KQIYQNEGFAAFYYSYPTTLAMNIPFAAFNFMIYESASKFFNPQNSYNPLIHCLCGGI
                     SGATCAALTTPLDCIKTVLQVRGSETVSIEIMKDANTFGRASRAILEVHGWKGFWRGL
                     KPRIVANIPATAISWTAYECAKHFLMKN"
     gene            complement(<534067..>535281)
                     /gene="YSR3"
                     /locus_tag="YKR053C"
                     /gene_synonym="LBP2"
                     /db_xref="GeneID:853927"
     mRNA            complement(<534067..>535281)
                     /gene="YSR3"
                     /locus_tag="YKR053C"
                     /gene_synonym="LBP2"
                     /product="sphinganine kinase YSR3"
                     /transcript_id="NM_001179843.3"
                     /db_xref="GI:398365194"
                     /db_xref="GeneID:853927"
     CDS             complement(534067..535281)
                     /gene="YSR3"
                     /locus_tag="YKR053C"
                     /gene_synonym="LBP2"
                     /EC_number="3.1.3.-"
                     /note="Dihydrosphingosine 1-phosphate phosphatase;
                     membrane protein involved in sphingolipid metabolism; YSR3
                     has a paralog, LCB3, that arose from the whole genome
                     duplication"
                     /codon_start=1
                     /product="sphinganine kinase YSR3"
                     /protein_id="NP_012979.3"
                     /db_xref="GI:398365195"
                     /db_xref="SGD:S000001761"
                     /db_xref="GeneID:853927"
                     /translation="MTIIQTVTELGVTEDTIKVQMAPSGGKHLLADPGNHPAEHFESQ
                     MSWLRFQTRQYLTRFTDNQSDFVHSLQKKHRTPFRDVYFKYTSLMGSHMFYVIVLPMP
                     VWLGYRDLTRDMIYVLGYSIYLSGYLKDYWCLPRPKSPPVDRITLSEYTTKEYGAPSS
                     HSANATAVSLLFFWRICLSDTLVWPTKLLLLSLVIFYYLTLVFGRVYCGMHGMLDLFS
                     GAAVGAICFFIRIWVVHALRNFQIGEHLWFPLLSVAWGLFILFNHVRPIDECPCFEDS
                     VAFIGVVSGLDCSDWLTERYGWNLVCSRYASCGSKVFLRPLVGVASVIVWKDVISKTA
                     VYTLLIKLLRFHDDRSEKVHFHNETSEEEECLLYSGVSKVEIVGRFLIYAGIPTTVFL
                     LCPVFFTWTNLR"
     gene            complement(<535647..>547925)
                     /gene="DYN1"
                     /locus_tag="YKR054C"
                     /gene_synonym="DHC1; PAC6"
                     /db_xref="GeneID:853928"
     mRNA            complement(<535647..>547925)
                     /gene="DYN1"
                     /locus_tag="YKR054C"
                     /gene_synonym="DHC1; PAC6"
                     /product="dynein heavy chain"
                     /transcript_id="NM_001179844.1"
                     /db_xref="GI:296146425"
                     /db_xref="GeneID:853928"
     CDS             complement(535647..547925)
                     /gene="DYN1"
                     /locus_tag="YKR054C"
                     /gene_synonym="DHC1; PAC6"
                     /note="Cytoplasmic heavy chain dynein; microtubule motor
                     protein; member of the AAA+ protein family, required for
                     anaphase spindle elongation; involved in spindle assembly,
                     chromosome movement, and spindle orientation during cell
                     division, targeted to microtubule tips by Pac1p; motility
                     along microtubules inhibited by She1p"
                     /codon_start=1
                     /product="dynein heavy chain"
                     /protein_id="NP_012980.1"
                     /db_xref="GI:6322907"
                     /db_xref="SGD:S000001762"
                     /db_xref="GeneID:853928"
                     /translation="MCKNEARLANELIEFVAATVTGIKNSPKENEQAFIDYLHCQYLE
                     RFQFFLGLLDGREFDTLFVFLFEELDRTIVTIDIGEEAIYDANLANKKYSTLLIIKSR
                     SVIVDAEPIATQISAIYLPGPVNAGNLASIITHGVSSVFGQLIKSDTKTYSVETIDKT
                     RRKLDDISKQFQQLHTSIETPDLLAMVPSIIKLAVSKGATSHDYANYLPSNDLESMRF
                     LNILQSIANKWFLVLKQTLAIDRDIKNGSFLDEVEFWSNFYEVLKSLIEQTQSQEFQV
                     CLSVLTNAKRFHNLTNLLNEGSLSDKFKLADKYNQFLSSIPIDEVRQASNLEDLQELF
                     PVLASSLKKFRYSGYPVQRFVVLMDKISQEVMDAILSNLSDLFQLEYGSFLGLYEKSA
                     GMIEEWDDIVQDVNLLIREDLRKRAPQELLIQKLTFTSASVKATLDEILSTRKRFFSL
                     AETIKSISPSTYHEEIQRLYHPFEQIHDISVNFRLKLEQAESEFSKNMLDLEKKLQNT
                     LASFMDSDHCPTEKLSYLVKFKPLMELCPRIKVKVLENQQILLLEIKKDIRQLETGLE
                     LLPKILHVEALNNIPPISARISYFLNVQSRIDNIVQYLEALFGSNWNDTLEGRSISTS
                     IVQLRKETNPHDVFLHWLGNFPEKATANLLTTPILKLIRNNEDDYELKVNFDFALAAA
                     YSELRSLTYMAFQVPSHIVRIARTYMYLYPRAINLVELIQTFFSLSKSLSYTFYTNIF
                     LKRNVQTVWLLLQQILITPWESLQEESSEMSCSVHSLARLEKSIDGILSDYQILKNSE
                     PQFAKEFSGLKSFDGTADDLHEVEEIISNIQAIFENLFTKGLTNVSDHISTFNNLIIS
                     IILEKVRLNLKKMHFPKHVLKLSFNEGRITSSPSLAAMKRSLLKDIEALLNKVVLINF
                     LHDPDHPLSTTLTFNSLVIKLKDDIQNCIEQVQNLHCKINSYVKEWQKMEFLWQITEE
                     AFLEVVDNSTQRCFGILKGLLDSQSKFDLIISRNNFSKNLVLHTEDAQRHIRSKMDSW
                     ILYVSKHLLTIYERDARKLHEDMNRDREAVEDMDINFTSLKNITVIIEAVNVNKRHLT
                     ERDIQIKLLGSVMRALTKLKVRFPSHFVYIDQLDNDFSSLRQSLSYVEQELQKHRVVI
                     AKSLEEGVENINNLSQSLNESWSVRKPISPTLTPPEALKILEFFNESITKLKKKMHSV
                     AAAAKMLLIPVVLNDQLTHVVEEVKTYDLVWRSIKNLWEDVQRTFETPWCRVDVLLLQ
                     SDLANFLRRADELPRAVKQFEMYKSLFSQVNMLTSVNKILVELKDGALKPRHWNMIFR
                     DIGKRQIQKNLLDKLEFSLKDVMVLNLTLNEILLTKIIERAQKEFVIEKSLNRIKKFW
                     KEAQYEVIEHSSGLKLVREWDVLEQACKEDLEELVSMKASNYYKIFEQDCLDLESKLT
                     KLSEIQVNWVEVQFYWLDLYGILGENLDIQNFLPLETSKFKSLTSEYKMITTRAFQLD
                     TTIEVIHIPNFDTTLKLTIDSLKMIKSSLSTFLERQRRQFPRFYFLGNDDLLKIIGSG
                     KHHDQVSKFMKKMFGSIESIIFLEDFITGVRSVEGEVLNLNEKIELKDSIQAQEWLNI
                     LDTEIKLSVFTQFRDCLGQLKDGTDIEVVVSKYIFQAILLSAQVMWTELVEKCLQTNQ
                     FSKYWKEVDMKIKGLLDKLNKSSDNVKKKIEALLVEYLHFNNVIGQLKNCSTKEEARL
                     LWAKVQKFYQKNDTLDDLNSVFISQSGYLLQYKFEYIGIPERLIYTPLLLIGFATLTD
                     SLHQKYGGCFFGPAGTGKTETVKAFGQNLGRVVVVFNCDDSFDYQVLSRLLVGITQIG
                     AWGCFDEFNRLDEKVLSAVSANIQQIQNGLQVGKSHITLLEEETPLSPHTAVFITLNP
                     GYNGRSELPENLKKSFREFSMKSPQSGTIAEMILQIMGFEDSKSLASKIVHFLELLSS
                     KCSSMNHYHFGLRTLKGVLRNCSPLISEFGEGEKTVVESLKRVILPSLGDTDELVFKD
                     ELSKIFDSAGTPLNSKAIVQCLKDAGQRSGFSMSEEFLKKCMQFYYMQKTQQALILVG
                     KAGCGKTATWKTVIDAMAIFDGHANVVYVIDTKVLTKESLYGSMLKATLEWRDGLFTS
                     ILRRVNDDITGTFKNSRIWVVFDSDLDPEYVEAMNSVLDDNKILTLPNGERLPIPPNF
                     RILFETDNLDHTTPATITRCGLLWFSTDVCSISSKIDHLLNKSYEALDNKLSMFELDK
                     LKDLISDSFDMASLTNIFTCSNDLVHILGVRTFNKLETAVQLAVHLISSYRQWFQNLD
                     DKSLKDVITLLIKRSLLYALAGDSTGESQRAFIQTINTYFGHDSQELSDYSTIVIAND
                     KLSFSSFCSEIPSVSLEAHEVMRPDIVIPTIDTIKHEKIFYDLLNSKRGIILCGPPGS
                     GKTMIMNNALRNSSLYDVVGINFSKDTTTEHILSALHRHTNYVTTSKGLTLLPKSDIK
                     NLVLFCDEINLPKLDKYGSQNVVLFLRQLMEKQGFWKTPENKWVTIERIHIVGACNPP
                     TDPGRIPMSERFTRHAAILYLGYPSGKSLSQIYEIYYKAIFKLVPEFRSYTEPFARAS
                     VHLYNECKARYSTGLQSHYLFSPRELTRLVRGVYTAINTGPRQTLRSLIRLWAYEAWR
                     IFADRLVGVKEKNSFEQLLYETVDKYLPNQDLGNISSTSLLFSGLLSLDFKEVNKTDL
                     VNFIEERFKTFCDEELEVPMVIHESMVDHILRIDRALKQVQGHMMLIGASRTGKTILT
                     RFVAWLNGLKIVQPKIHRHSNLSDFDMILKKAISDCSLKESRTCLIIDESNILETAFL
                     ERMNTLLANADIPDLFQGEEYDKLLNNLRNKTRSLGLLLDTEQELYDWFVGEIAKNLH
                     VVFTICDPTNNKSSAMISSPALFNRCIINWMGDWDTKTMSQVANNMVDVIPMEFTDFI
                     VPEVNKELVFTEPIQTIRDAVVNILIHFDRNFYQKMKVGVNPRSPGYFIDGLRALVKL
                     VTAKYQDLQENQRFVNVGLEKLNESVLKVNELNKTLSKKSTELTEKEKEARSTLDKML
                     MEQNESERKQEATEEIKKILKVQEEDIRKRKEVVMKSIQDIEPTILEAQRGVKNIKKQ
                     QLTEIRSMVNPPSGVKIVMEAVCAILGYQFSNWRDIQQFIRKDDFIHNIVHYDTTLHM
                     KPQIRKYMEEEFLSDPNFTYETINRASKACGPLYQWVNAQINFSKVLENVDPLRQEMK
                     RIEFESLKTKANLLAAEEMTQDLEASIEVSKRKYSLLIRDVEAIKTEMSNVQANLDRS
                     ISLVKSLTFEKERWLNTTKQFSKTSQELIGNCIISSIYETYFGHLNERERADMLVILK
                     RLLGKFAVKYDVNYRFIDYLVTLDEKMKWLECGLDKNDYFLENMSIVMNSQDAVPFLL
                     DPSSHMITVISNYYGNKTVLLSFLEEGFVKRLENAIRFGSVVIIQDGEFFDPIISRLI
                     SREFNHAGNRVTVEIGDHEVDVSGDFKLFIHSCDPSGDIPIFLRSRVRLVHFVTNKES
                     IETRIFDITLTEENAEMQRKREDLIKLNTEYKLKLKNLEKRLLEELNNSQGNMLENDE
                     LMVTLNNLKKEAMNIEKKLSESEEFFPQFDNLVEEYSIIGKHSVKIFSMLEKFGQFHW
                     FYGISIGQFLSCFKRVFIKKSRETRAARTRVDEILWLLYQEVYCQFSTALDKKFKMIM
                     AMTMFCLYKFDIESEQYKEAVLTMIGVLSESSDGVPKLTVDTNNDLRYLWDYVTTKSY
                     ISALNWFKNEFFVDEWNIADVVANSENNYFTMASERDVDGTFKLIELAKASKESLKII
                     PLGSIENLNYAQEEISKSKIEGGWILLQNIQMSLSWVKTYLHKHVEETKAAEEHEKFK
                     MFMTCHLTGDKLPAPLLQRTDRFVYEDIPGILDTVKDLWGSQFFTGKISGVWSVYCTF
                     LLSWFHALITARTRLVPHGFSKKYYFNDCDFQFASVYLENVLATNSTNNIPWAQVRDH
                     IATIVYGGKIDEEKDLEVVAKLCAHVFCGSDNLQIVPGVRIPQPLLQQSEEEERARLT
                     AILSNTIEPADSLSSWLQLPRESILNYERLQAKEVASSTEQLLQEM"
     gene            <548216..>549091
                     /gene="RHO4"
                     /locus_tag="YKR055W"
                     /db_xref="GeneID:853929"
     mRNA            <548216..>549091
                     /gene="RHO4"
                     /locus_tag="YKR055W"
                     /product="Rho family GTPase RHO4"
                     /transcript_id="NM_001179845.3"
                     /db_xref="GI:398365216"
                     /db_xref="GeneID:853929"
     CDS             548216..549091
                     /gene="RHO4"
                     /locus_tag="YKR055W"
                     /note="Non-essential small GTPase; member of the Rho/Rac
                     subfamily of Ras-like proteins; likely to be involved in
                     the establishment of cell polarity; has long N-terminal
                     extension that plays an important role in Rho4p function
                     and is shared with Rho4 homologs in other yeasts and
                     filamentous fungi"
                     /codon_start=1
                     /product="Rho family GTPase RHO4"
                     /protein_id="NP_012981.3"
                     /db_xref="GI:398365217"
                     /db_xref="SGD:S000001763"
                     /db_xref="GeneID:853929"
                     /translation="MNTLLFKRKGGNCGNESNIVSQGSPSSSNLPESPGTLDEKNLPR
                     LPTPFARSLSTIPSYEQMKRTNKLPDYHLKIVVVGDGAVGKTCLLISYVQGTFPTDYI
                     PTIFENYVTNIEGPNGQIIELALWDTAGQEEYSRLRPLSYTNADVLMVCYSVGSKTSL
                     KNVEDLWFPEVKHFCPSTPIMLVGLKSDLYEADNLSDLVEPSSAESLAKRLGAFAHIQ
                     CSARLKENIDEVFETAIHTLLSDSLYAPREPTHTIKNPFKRNTTRSDIDSSTGDTSVS
                     ISGTKRLRKNKCIIM"
     gene            <549448..>551367
                     /gene="TRM2"
                     /locus_tag="YKR056W"
                     /gene_synonym="NUC2; NUD1; RNC1"
                     /db_xref="GeneID:853930"
     mRNA            <549448..>551367
                     /gene="TRM2"
                     /locus_tag="YKR056W"
                     /gene_synonym="NUC2; NUD1; RNC1"
                     /product="Trm2p"
                     /transcript_id="NM_001179846.1"
                     /db_xref="GI:296146427"
                     /db_xref="GeneID:853930"
     CDS             549448..551367
                     /gene="TRM2"
                     /locus_tag="YKR056W"
                     /gene_synonym="NUC2; NUD1; RNC1"
                     /EC_number="2.1.1.35"
                     /note="tRNA methyltransferase; 5-methylates the uridine
                     residue at position 54 of tRNAs and may also have a role
                     in tRNA stabilization or maturation; endo-exonuclease with
                     a role in DNA repair"
                     /codon_start=1
                     /product="Trm2p"
                     /protein_id="NP_012982.2"
                     /db_xref="GI:42759862"
                     /db_xref="SGD:S000001764"
                     /db_xref="GeneID:853930"
                     /translation="MYEQFEFSFFFFENSDNKVKYKAHLISSIKRWSIITCMRCFWTV
                     QKSIFKARFFACRNFVKKHNYKLISTMTGSTEMVPPTMKHTVDNKRLSSPLTDSGNRR
                     TKKPKLRKYKAKKVETTSPMGVLEFEVNDLLKSQNLSREQVLNDVTSILNDKSSTDGP
                     IVLQYHREVKNVKVLEITSNGNGLALIDNPVETEKKQVVIIPFGLPGDVVNIKVFKTH
                     PYYVESDLLDVVEKSPMRRDDLIRDKYFGKSSGSQLEFLTYDDQLELKRKTIMNAYKF
                     FAPRLVAEKLLPPFDTTVASPLQFGYRTKITPHFDMPKRKQKELSVRPPLGFGQKGRP
                     QWRKDTLDIGGHGSILDIDECVLATEVLNKGLTNERRKFEQEFKNYKKGATILLRENT
                     TILDPSKPTLEQLTEEASRDENGDISYVEVEDKKNNVRLAKTCVTNPRQIVTEYVDGY
                     TFNFSAGEFFQNNNSILPIVTKYVRDNLQAPAKGDDNKTKFLVDAYCGSGLFSICSSK
                     GVDKVIGVEISADSVSFAEKNAKANGVENCRFIVGKAEKLFESIDTPSENTSVILDPP
                     RKGCDELFLKQLAAYNPAKIIYISCNVHSQARDVEYFLKETENGSAHQIESIRGFDFF
                     PQTHHVESVCIMKRI"
     gene            <551657..>552242
                     /gene="RPS21A"
                     /locus_tag="YKR057W"
                     /gene_synonym="RPS25"
                     /db_xref="GeneID:853931"
     mRNA            join(<551657..551680,552003..>552242)
                     /gene="RPS21A"
                     /locus_tag="YKR057W"
                     /gene_synonym="RPS25"
                     /product="ribosomal 40S subunit protein S21A"
                     /transcript_id="NM_001179847.3"
                     /db_xref="GI:398365232"
                     /db_xref="GeneID:853931"
     CDS             join(551657..551680,552003..552242)
                     /gene="RPS21A"
                     /locus_tag="YKR057W"
                     /gene_synonym="RPS25"
                     /note="Protein component of the small (40S) ribosomal
                     subunit; homologous to mammalian ribosomal protein S21, no
                     bacterial homolog; RPS21A has a paralog, RPS21B, that
                     arose from the whole genome duplication"
                     /codon_start=1
                     /product="ribosomal 40S subunit protein S21A"
                     /protein_id="NP_012983.3"
                     /db_xref="GI:398365233"
                     /db_xref="SGD:S000001765"
                     /db_xref="GeneID:853931"
                     /translation="MENDKGQLVELYVPRKCSATNRIIKADDHASVQINVAKVDEEGR
                     AIPGEYVTYALSGYVRSRGESDDSLNRLAQNDGLLKNVWSYSR"
     gene            <552770..>554620
                     /gene="GLG1"
                     /locus_tag="YKR058W"
                     /db_xref="GeneID:853932"
     mRNA            <552770..>554620
                     /gene="GLG1"
                     /locus_tag="YKR058W"
                     /product="glycogenin glucosyltransferase GLG1"
                     /transcript_id="NM_001179848.1"
                     /db_xref="GI:296146429"
                     /db_xref="GeneID:853932"
     CDS             552770..554620
                     /gene="GLG1"
                     /locus_tag="YKR058W"
                     /EC_number="2.4.1.186"
                     /note="Glycogenin glucosyltransferase; self-glucosylating
                     initiator of glycogen synthesis, also glucosylates
                     n-dodecyl-beta-D-maltoside; similar to mammalian
                     glycogenin; GLG1 has a paralog, GLG2, that arose from the
                     whole genome duplication"
                     /codon_start=1
                     /product="glycogenin glucosyltransferase GLG1"
                     /protein_id="NP_012984.2"
                     /db_xref="GI:83578103"
                     /db_xref="SGD:S000001766"
                     /db_xref="GeneID:853932"
                     /translation="MYKKLAIATLLYSADYLPGVFALGHQVNKLLEEAGKKGDIETCL
                     IVTTSLFNGTLSELAKNILQSIYTKIVLVEPLNCQEESIQKNSENLALLERPELSFAL
                     IKARLWELTQFEQVLYLDSDTLPLNKEFLKLFDIMSKQTTSQVGAIADIGWPDMFNSG
                     VMMLIPDADTASVLQNYIFENTSIDGSDQGILNQFFNQNCCTDELVKDSFSREWVQLS
                     FTYNVTIPNLGYQSSPAMNYFKPSIKLIHFIGKHKPWSLWSQKNFIKNEYHDQWNEVY
                     EEFKEEHQLNNEVSKPKISDSDKTETPETITPVDAPPSNEPTTNQEIDTISTVEENVD
                     NQNAEPVPNSDHSPAPNPVPLDFTKWLTTFINKDHLTNQPVNESREYSKENDNNIINS
                     SSNRDQESPPNSTQELNSSYSVVSTQADSDEHQNAEEEDSTTDNASNSGEESHLDDIS
                     TAASSNNNVSNQPDGKNFSNSKENNISVESSPSNPEQKRSTDNIQKPSVSTNDLPDDV
                     EPHTSVDDNIQYLEKDKEGYEEFLPDVYESNAIDNEEEFFDDDARDATEGETKTSAVA
                     DKQEDMKLTAEETNQPQQEMPNFKFDWEDSDYLSKVERCFPDDIFEYAVE"
     gene            <554987..>556174
                     /gene="TIF1"
                     /locus_tag="YKR059W"
                     /db_xref="GeneID:853933"
     mRNA            <554987..>556174
                     /gene="TIF1"
                     /locus_tag="YKR059W"
                     /product="translation initiation factor eIF4A"
                     /transcript_id="NM_001179849.3"
                     /db_xref="GI:398365252"
                     /db_xref="GeneID:853933"
     CDS             554987..556174
                     /gene="TIF1"
                     /locus_tag="YKR059W"
                     /EC_number="3.6.4.13"
                     /note="Translation initiation factor eIF4A; DEA(D/H)-box
                     RNA helicase that couples ATPase activity to RNA binding
                     and unwinding; forms a dumbbell structure of two compact
                     domains connected by a linker; interacts with eIF4G;
                     protein abundance increases in response to DNA replication
                     stress; TIF1 has a paralog, TIF2, that arose from the
                     whole genome duplication"
                     /codon_start=1
                     /product="translation initiation factor eIF4A"
                     /protein_id="NP_012985.3"
                     /db_xref="GI:398365253"
                     /db_xref="SGD:S000001767"
                     /db_xref="GeneID:853933"
                     /translation="MSEGITDIEESQIQTNYDKVVYKFDDMELDENLLRGVFGYGFEE
                     PSAIQQRAIMPIIEGHDVLAQAQSGTGKTGTFSIAALQRIDTSVKAPQALMLAPTREL
                     ALQIQKVVMALAFHMDIKVHACIGGTSFVEDAEGLRDAQIVVGTPGRVFDNIQRRRFR
                     TDKIKMFILDEADEMLSSGFKEQIYQIFTLLPPTTQVVLLSATMPNDVLEVTTKFMRN
                     PVRILVKKDELTLEGIKQFYVNVEEEEYKYECLTDLYDSISVTQAVIFCNTRRKVEEL
                     TTKLRNDKFTVSAIYSDLPQQERDTIMKEFRSGSSRILISTDLLARGIDVQQVSLVIN
                     YDLPANKENYIHRIGRGGRFGRKGVAINFVTNEDVGAMRELEKFYSTQIEELPSDIAT
                     LLN"
     gene            <556518..>557342
                     /gene="UTP30"
                     /locus_tag="YKR060W"
                     /db_xref="GeneID:853934"
     mRNA            <556518..>557342
                     /gene="UTP30"
                     /locus_tag="YKR060W"
                     /product="Utp30p"
                     /transcript_id="NM_001179850.1"
                     /db_xref="GI:296146431"
                     /db_xref="GeneID:853934"
     CDS             556518..557342
                     /gene="UTP30"
                     /locus_tag="YKR060W"
                     /note="Putative subunit of U3-containing 90S preribosome
                     complex; complex is involved in production of 18S rRNA and
                     assembly of small ribosomal subunit"
                     /codon_start=1
                     /product="Utp30p"
                     /protein_id="NP_012986.1"
                     /db_xref="GI:6322913"
                     /db_xref="SGD:S000001768"
                     /db_xref="GeneID:853934"
                     /translation="MVESNDIIKSGLAEKALKALILQCEENPSLKNDKDIHIIINTGK
                     KMGINRDNIPRIIPLTKYKLFKPRDLNILLITKDPSALYRETLTKDEHTSELFKEIIS
                     VKNLRRRFKGSKLTQLYKDFDLVVADYRVHHLLPEVLGSRFYHGSKKLPYMIRMSKEV
                     KLKRQQMVEKCDPIYVRAQLRSICKNTSYIPNNDNCLSVRVGYIQKHSIPEILQNIQD
                     TINFLTDKSKRPQGGVIKGGIISIFVKTSNSTSLPIYQFSEARENQKNEDLSDIKL"
     gene            <557677..>558954
                     /gene="KTR2"
                     /locus_tag="YKR061W"
                     /db_xref="GeneID:853935"
     mRNA            <557677..>558954
                     /gene="KTR2"
                     /locus_tag="YKR061W"
                     /product="mannosyltransferase KTR2"
                     /transcript_id="NM_001179851.3"
                     /db_xref="GI:398365274"
                     /db_xref="GeneID:853935"
     CDS             557677..558954
                     /gene="KTR2"
                     /locus_tag="YKR061W"
                     /EC_number="2.4.1.-"
                     /note="Mannosyltransferase involved in N-linked protein
                     glycosylation; member of the KRE2/MNT1 mannosyltransferase
                     family; KTR2 has a paralog, YUR1, that arose from the
                     whole genome duplication"
                     /codon_start=1
                     /product="mannosyltransferase KTR2"
                     /protein_id="NP_012987.3"
                     /db_xref="GI:398365275"
                     /db_xref="SGD:S000001769"
                     /db_xref="GeneID:853935"
                     /translation="MQICKVFLTQVKKLLFVSLLFCLIAQTCWLALVPYQRQLSLDSY
                     FFRRSREVSSRYDFTRRRHMNQTLKLSSNTYNDEPLNKTKGIKNQRENATLLMLVRNW
                     ELSGALRSMRSLEDRFNKNYQYDWTFLNDVPFDQEFIEATTAMASGRTQYALIPAEDW
                     NRPSWINETLFEEALQLMEEKNILYGGSKSYRNMCRFNSGFFFRQKILDPYDFYFRVE
                     PDVEYFCDFPYDPFKVMRQNNKKYGFVITMYEYEDTIPSLWEAVEEYLEETESADIDM
                     ESNAFGFVSNFDFIGKSFGVIDSNSGYNLCHFWTNFEIGDLNFFRSEKYIRFFEYLDS
                     KGGFYYERWGDAPVHSIAASLLLKKDEIIHFDELGYKHMPFGTCPSAYYLRLQQRCLC
                     DSNHPDNIDLNVISCLRRWWKDGSGKYFLKHDS"
     gene            complement(559016..559366)
                     /locus_tag="snR42"
                     /db_xref="GeneID:9164915"
     ncRNA           complement(559016..559366)
                     /locus_tag="snR42"
                     /ncRNA_class="snoRNA"
                     /product="SNR42"
                     /note="H/ACA box small nucleolar RNA (snoRNA); guides
                     pseudouridylation of large subunit (LSU) rRNA at position
                     U2975"
                     /transcript_id="NR_132203.1"
                     /db_xref="GI:831416128"
                     /db_xref="SGD:S000006502"
                     /db_xref="GeneID:9164915"
     gene            <559666..>560652
                     /gene="TFA2"
                     /locus_tag="YKR062W"
                     /db_xref="GeneID:853936"
     mRNA            <559666..>560652
                     /gene="TFA2"
                     /locus_tag="YKR062W"
                     /product="Tfa2p"
                     /transcript_id="NM_001179852.1"
                     /db_xref="GI:296146433"
                     /db_xref="GeneID:853936"
     CDS             559666..560652
                     /gene="TFA2"
                     /locus_tag="YKR062W"
                     /note="TFIIE small subunit; involved in RNA polymerase II
                     transcription initiation"
                     /codon_start=1
                     /product="Tfa2p"
                     /protein_id="NP_012988.1"
                     /db_xref="GI:6322915"
                     /db_xref="SGD:S000001770"
                     /db_xref="GeneID:853936"
                     /translation="MSKNRDPLLANLNAFKSKVKSAPVIAPAKVGQKKTNDTVITIDG
                     NTRKRTASERAQENTLNSAKNPVLVDIKKEAGSNSSNAISLDDDDDDEDFGSSPSKKV
                     RPGSIAAAALQANQTDISKSHDSSKLLWATEYIQKKGKPVLVNELLDYLSMKKDDKVI
                     ELLKKLDRIEFDPKKGTFKYLSTYDVHSPSELLKLLRSQVTFKGISCKDLKDGWPQCD
                     ETINQLEEDSKILVLRTKKDKTPRYVWYNSGGNLKCIDEEFVKMWENVQLPQFAELPR
                     KLQDLGLKPASVDPATIKRQTKRVEVKKKRQRKGKITNTHMTGILKDYSHRV"
     gene            complement(<560789..>562297)
                     /gene="LAS1"
                     /locus_tag="YKR063C"
                     /db_xref="GeneID:853937"
     mRNA            complement(<560789..>562297)
                     /gene="LAS1"
                     /locus_tag="YKR063C"
                     /product="Las1p"
                     /transcript_id="NM_001179853.3"
                     /db_xref="GI:398365292"
                     /db_xref="GeneID:853937"
     CDS             complement(560789..562297)
                     /gene="LAS1"
                     /locus_tag="YKR063C"
                     /note="Protein required for pre-rRNA processing at both
                     ends of ITS2; functions with Grc3p in a conserved
                     mechanism to modulate rRNA processing and ribosome
                     biogenesis; may coordinate the action of the Rat1p-Rai1p
                     exoRNAse; required for the G1/S cell cycle transition;
                     human ortholog is Las1L; mutants require the SSD1-v allele
                     for viability"
                     /codon_start=1
                     /product="Las1p"
                     /protein_id="NP_012989.3"
                     /db_xref="GI:398365293"
                     /db_xref="SGD:S000001771"
                     /db_xref="GeneID:853937"
                     /translation="MIPPRIVPWRDFAELEELKLWFYPKSKGTIEDKRQRAVQRVQSY
                     RLKGSQYLPHVVDSTAQITCAVLLDEKEACLGVHQDSIPIRLSYVMALIRFVNGLLDP
                     TQQSQFAIPLHTLAAKIGLPSWFVDLRHWGTHERDLPGLEMLRWAANEALSWLYDHYW
                     NDEELEDDRDDDDDDDDTGYGYRRNDKLEKYMESLTKTLDKWKRLRNEFLEYKWVWEN
                     ANDSLITSSNFSGDNLVNYDAEKRKSSHASSSETMIRENLRQWQELWKLSIYHNVVLE
                     KFFNNYDPLLLKVLMLNLNNFDWKVIEWVARNYRTQQDDSNITTILKRKFNAWKELQK
                     RLLDVIINNLNNKNFKNKWQNWEKLIDENASYLILYFCQSMLAKLETEKITGNSWRNK
                     KRRKQIDSTVEIEAKLKENIDNLSLRFNEGEIKLYDFIPAEKDSVPLKKEVSPALKAD
                     TNDILGDLASLKQRMSSFGTVGKKNKQEENRATPVKNWSRVQNWKPKPFGVL"
     gene            <562547..>565138
                     /gene="OAF3"
                     /locus_tag="YKR064W"
                     /db_xref="GeneID:853938"
     mRNA            <562547..>565138
                     /gene="OAF3"
                     /locus_tag="YKR064W"
                     /product="Oaf3p"
                     /transcript_id="NM_001179854.1"
                     /db_xref="GI:296146435"
                     /db_xref="GeneID:853938"
     CDS             562547..565138
                     /gene="OAF3"
                     /locus_tag="YKR064W"
                     /note="Putative transcriptional repressor with
                     Zn(2)-Cys(6) finger; negatively regulates transcription in
                     response to oleate levels, based on mutant phenotype and
                     localization to oleate-responsive promoters; the
                     authentic, non-tagged protein is detected in highly
                     purified mitochondria in high-throughput studies; forms
                     nuclear foci upon DNA replication stress"
                     /codon_start=1
                     /product="Oaf3p"
                     /protein_id="NP_012990.1"
                     /db_xref="GI:6322917"
                     /db_xref="SGD:S000001772"
                     /db_xref="GeneID:853938"
                     /translation="MGYDSQVRTKKRHRITVVCTNCKKRKSKCDRTKPCGTCVRLGDV
                     DSCVYLTDSSGQPESSPSLNDADPLRKQSTPAERISPGFIKKRRSSQTRQDEDHWQRV
                     RELENQSSLYYLPIHEETPFFIDLIPNGFYLETKRSADNLFGLFTDRAIENRDPYLQA
                     MVTFRSIAIKKMMDKLGSNGNNVKNGSLPKSFEALSTFDADDERHISDDVVGKGNNFR
                     MHQTIHKSLFNKFAQYRENNAKKFSSETILAKDYLPPLKILESEVLALFEEKIYNMIP
                     IFDMKVLRHEITIFYQNIVEKGNPISIKHYDHMVFCIILLIIKICRLSVQFSKLTPYI
                     YPVLQEIDTSKFLALVKHYLFETKVLRKCNLLQLQCLILLRFLHWCAPEDGDGPETQY
                     CQILMGTIISSCKEMGINWYCFSHPEKYSFKINRHTRPSYDIMKPSDYISVFRKIWSY
                     VLFWDRKMCFISGEECQIGKTLQCHFKEEADTPTWYIRMLTLDNLMKKINDTLNDDPG
                     KVDLNLLHRLINDLKRNFHILKSLSKNEKETMRHFDFEMEWIIDLFSLSLLHGEMIFY
                     EYDCNITKFYKSFQDLWDMVIHISEKCYNYFFNSDALEVDSLTKFYTNRIVEIVANKV
                     LVIVPAFILRGDRFKTIQYADKKKMIEFLYGVSSVYFNEFGFEYYRCFRKMFTAKIAY
                     KILNRSCEKDAWRIILKFLLNELKLEDNGDSYIDYNDMRLNDICPIILEFQETVQKYD
                     GYRPDILSIWNNEFYPIGKYNDDMTGFKFQMRIKEMQEFLDMEKYSDRFNIFSSFYDH
                     ASSQLAKHTEVDTNISITNEQVAEIPQKELLQQPLAPALPVNDLIVSEFDVIEDIFDP
                     VDFVSFF"
     gene            complement(<565299..>565892)
                     /gene="PAM17"
                     /locus_tag="YKR065C"
                     /gene_synonym="FMP18"
                     /db_xref="GeneID:853939"
     mRNA            complement(<565299..>565892)
                     /gene="PAM17"
                     /locus_tag="YKR065C"
                     /gene_synonym="FMP18"
                     /product="Pam17p"
                     /transcript_id="NM_001179855.3"
                     /db_xref="GI:398365304"
                     /db_xref="GeneID:853939"
     CDS             complement(565299..565892)
                     /gene="PAM17"
                     /locus_tag="YKR065C"
                     /gene_synonym="FMP18"
                     /note="Constituent of the TIM23 complex; proposed
                     alternatively to be a component of the import motor (PAM
                     complex) or to interact with and modulate the core TIM23
                     (Translocase of the Inner mitochondrial Membrane) complex;
                     protein abundance increases in response to DNA replication
                     stress"
                     /codon_start=1
                     /product="Pam17p"
                     /protein_id="NP_012991.3"
                     /db_xref="GI:398365305"
                     /db_xref="SGD:S000001773"
                     /db_xref="GeneID:853939"
                     /translation="MFTSAIRLSSQRLFASQPSVTAAALRSTATTLPLRSYSQPASLQ
                     DSSILTWSDFFKLRKQQRRINVGSSLFTALLGCNVSWAYLSTMEIDPTQMLFGFDPLT
                     VISAGIIASGALGYLLGPIVGSQVFKLSHNQQLAQFNNKNKEFLKHIINNRVDASSQS
                     FSNPVPDYYGEKIGSLKEYKQWLRDCHAYAKKAKEFL"
     gene            complement(<566113..>567198)
                     /gene="CCP1"
                     /locus_tag="YKR066C"
                     /db_xref="GeneID:853940"
     mRNA            complement(<566113..>567198)
                     /gene="CCP1"
                     /locus_tag="YKR066C"
                     /product="Ccp1p"
                     /transcript_id="NM_001179856.1"
                     /db_xref="GI:296146437"
                     /db_xref="GeneID:853940"
     CDS             complement(566113..567198)
                     /gene="CCP1"
                     /locus_tag="YKR066C"
                     /EC_number="1.11.1.5"
                     /note="Mitochondrial cytochrome-c peroxidase; degrades
                     reactive oxygen species in mitochondria, involved in the
                     response to oxidative stress"
                     /codon_start=1
                     /product="Ccp1p"
                     /protein_id="NP_012992.1"
                     /db_xref="GI:6322919"
                     /db_xref="SGD:S000001774"
                     /db_xref="GeneID:853940"
                     /translation="MTTAVRLLPSLGRTAHKRSLYLFSAAAAAAAAATFAYSQSQKRS
                     SSSPGGGSNHGWNNWGKAAALASTTPLVHVASVEKGRSYEDFQKVYNAIALKLREDDE
                     YDNYIGYGPVLVRLAWHTSGTWDKHDNTGGSYGGTYRFKKEFNDPSNAGLQNGFKFLE
                     PIHKEFPWISSGDLFSLGGVTAVQEMQGPKIPWRCGRVDTPEDTTPDNGRLPDADKDA
                     DYVRTFFQRLNMNDREVVALMGAHALGKTHLKNSGYEGPWGAANNVFTNEFYLNLLNE
                     DWKLEKNDANNEQWDSKSGYMMLPTDYSLIQDPKYLSIVKEYANDQDKFFKDFSKAFE
                     KLLENGITFPKDAPSPFIFKTLEEQGL"
     gene            <567918..>570149
                     /gene="GPT2"
                     /locus_tag="YKR067W"
                     /gene_synonym="GAT1"
                     /db_xref="GeneID:853941"
     mRNA            <567918..>570149
                     /gene="GPT2"
                     /locus_tag="YKR067W"
                     /gene_synonym="GAT1"
                     /product="bifunctional
                     glycerol-3-phosphate/glycerone-phosphate O-acyltransferase
                     GPT2"
                     /transcript_id="NM_001179857.3"
                     /db_xref="GI:398365316"
                     /db_xref="GeneID:853941"
     CDS             567918..570149
                     /gene="GPT2"
                     /locus_tag="YKR067W"
                     /gene_synonym="GAT1"
                     /EC_number="2.3.1.42"
                     /EC_number="2.3.1.15"
                     /note="Glycerol-3-phosphate/dihydroxyacetone phosphate
                     sn-1 acyltransferase; located in lipid particles and the
                     ER; involved in the stepwise acylation of
                     glycerol-3-phosphate and dihydroxyacetone in lipid
                     biosynthesis; the most conserved motifs and functionally
                     relevant residues are oriented towards the ER lumen"
                     /codon_start=1
                     /product="bifunctional
                     glycerol-3-phosphate/glycerone-phosphate O-acyltransferase
                     GPT2"
                     /protein_id="NP_012993.3"
                     /db_xref="GI:398365317"
                     /db_xref="SGD:S000001775"
                     /db_xref="GeneID:853941"
                     /translation="MSAPAADHNAAKPIPHVPQASRRYKNSYNGFVYNIHTWLYDVSV
                     FLFNILFTIFFREIKVRGAYNVPEVGVPTILVCAPHANQFIDPALVMSQTRLLKTSAG
                     KSRSRMPCFVTAESSFKKRFISFFGHAMGGIPVPRIQDNLKPVDENLEIYAPDLKNHP
                     EIIKGRSKNPQTTPVNFTKRFSAKSLLGLPDYLSNAQIKEIPDDETIILSSPFRTSKS
                     KVVELLTNGTNFKYAEKIDNTETFQSVFDHLHTKGCVGIFPEGGSHDRPSLLPIKAGV
                     AIMALGAVAADPTMKVAVVPCGLHYFHRNKFRSRAVLEYGEPIVVDGKYGEMYKDSPR
                     ETVSKLLKKITNSLFSVTENAPDYDTLMVIQAARRLYQPVKVRLPLPAIVEINRRLLF
                     GYSKFKDDPRIIHLKKLVYDYNRKLDSVGLKDHQVMQLKTTKLEALRCFVTLIVRLIK
                     FSVFAILSLPGSILFTPIFIICRVYSEKKAKEGLKKSLVKIKGTDLLATWKLIVALIL
                     APILYVTYSILLIILARKQHYCRIWVPSNNAFIQFVYFYALLVFTTYSSLKTGEIGVD
                     LFKSLRPLFVSIVYPGKKIEEIQTTRKNLSLELTAVCNDLGPLVFPDYDKLATEIFSK
                     RDGYDVSSDAESSISRMSVQSRSRSSSIHSIGSLASNALSRVNSRGSLTDIPIFSDAK
                     QGQWKSEGETSEDEDEFDEKNPAIVQTARSSDLNKENSRNTNISSKIASLVRQKREHE
                     KKE"
     gene            complement(<570328..>570909)
                     /gene="BET3"
                     /locus_tag="YKR068C"
                     /db_xref="GeneID:853942"
     mRNA            complement(<570328..>570909)
                     /gene="BET3"
                     /locus_tag="YKR068C"
                     /product="TRAPP complex core subunit BET3"
                     /transcript_id="NM_001179858.1"
                     /db_xref="GI:296146439"
                     /db_xref="GeneID:853942"
     CDS             complement(570328..570909)
                     /gene="BET3"
                     /locus_tag="YKR068C"
                     /note="Core component of transport protein particle
                     (TRAPP) complexes I-III; TRAPP complexes are related
                     multimeric guanine nucleotide-exchange factors for the
                     GTPase Ypt1, regulating ER-Golgi traffic (TRAPPI),
                     intra-Golgi traffic (TRAPPII), endosome-Golgi traffic
                     (TRAPPII and III) and autophagy (TRAPPIII); hydrophilic
                     homodimeric protein that acts in conjunction with SNARE
                     proteins in targeting and fusion of ER to Golgi transport
                     vesicles"
                     /codon_start=1
                     /product="TRAPP complex core subunit BET3"
                     /protein_id="NP_012994.1"
                     /db_xref="GI:6322921"
                     /db_xref="SGD:S000001776"
                     /db_xref="GeneID:853942"
                     /translation="MVSTTQSRSLKAMGEEIWKNKTEKINTELFTLTYGSIVAQLCQD
                     YERDFNKVNDHLYSMGYNIGCRLIEDFLARTALPRCENLVKTSEVLSKCAFKIFLNIT
                     PNITNWSHNKDTFSLILDENPLADFVELPMDAMKSLWYSNILCGVLKGSLEMVQLDCD
                     VWFVSDILRGDSQTEIKVKLNRILKDEIPIGED"
     gene            <571612..>573393
                     /gene="MET1"
                     /locus_tag="YKR069W"
                     /gene_synonym="MET20"
                     /db_xref="GeneID:853943"
     mRNA            <571612..>573393
                     /gene="MET1"
                     /locus_tag="YKR069W"
                     /gene_synonym="MET20"
                     /product="uroporphyrinogen-III C-methyltransferase"
                     /transcript_id="NM_001179859.3"
                     /db_xref="GI:398365328"
                     /db_xref="GeneID:853943"
     CDS             571612..573393
                     /gene="MET1"
                     /locus_tag="YKR069W"
                     /gene_synonym="MET20"
                     /EC_number="2.1.1.107"
                     /note="S-adenosyl-L-methionine uroporphyrinogen III
                     transmethylase; involved in the biosynthesis of siroheme,
                     a prosthetic group used by sulfite reductase; required for
                     sulfate assimilation and methionine biosynthesis"
                     /codon_start=1
                     /product="uroporphyrinogen-III C-methyltransferase"
                     /protein_id="NP_012995.3"
                     /db_xref="GI:398365329"
                     /db_xref="SGD:S000001777"
                     /db_xref="GeneID:853943"
                     /translation="MVRDLVTLPSSLPLITAGFATDQVHLLIGTGSTDSVSVCKNRIH
                     SILNAGGNPIVVNPSSPSHTKQLQLEFGKFAKFEIVEREFRLSDLTTLGRVLVCKVVD
                     RVFVDLPITQSRLCEEIFWQCQKLRIPINTFHKPEFSTFNMIPTWVDPKGSGLQISVT
                     TNGNGYILANRIKRDIISHLPPNISEVVINMGYLKDRIINEDHKALLEEKYYQTDMSL
                     PGFGYGLDEDGWESHKFNKLIREFEMTSREQRLKRTRWLSQIMEYYPMNKLSDIKLED
                     FETSSSPNKKTKQETVTEGVVPPTDENIENGTKQLQLSEVKKEEGPKKLGKISLVGSG
                     PGSVSMLTIGALQEIKSADIILADKLVPQAILDLIPPKTETFIAKKFPGNAERAQQEL
                     LAKGLESLDNGLKVVRLKQGDPYIFGRGGEEFNFFKDHGYIPVVLPGISSSLACTVLA
                     QIPATQRDIADQVLICTGTGRKGALPIIPEFVESRTTVFLMALHRANVLITGLLKHGW
                     DGDVPAAIVERGSCPDQRVTRTLLKWVPEVVEEIGSRPPGVLVVGKAVNALVEKDLIN
                     FDESRKFVIDEGFREFEVDVDSLFKLY"
     gene            <573574..>574632
                     /locus_tag="YKR070W"
                     /db_xref="GeneID:853944"
     mRNA            <573574..>574632
                     /locus_tag="YKR070W"
                     /product="hypothetical protein"
                     /transcript_id="NM_001179860.1"
                     /db_xref="GI:296146441"
                     /db_xref="GeneID:853944"
     CDS             573574..574632
                     /locus_tag="YKR070W"
                     /note="hypothetical protein; the authentic, non-tagged
                     protein is detected in highly purified mitochondria in
                     high-throughput studies"
                     /codon_start=1
                     /product="hypothetical protein"
                     /protein_id="NP_012996.1"
                     /db_xref="GI:6322923"
                     /db_xref="SGD:S000001778"
                     /db_xref="GeneID:853944"
                     /translation="MIGKRFFQTTSKKIAFAFDIDGVLFRGKKPIAGASDALKLLNRN
                     KIPYILLTNGGGFSERARTEFISSKLDVDVSPLQIIQSHTPYKSLVNKYSRILAVGTP
                     SVRGVAEGYGFQDVVHQTDIVRYNRDIAPFSGLSDEQVMEYSRDIPDLTTKKFDAVLV
                     FNDPHDWAADIQIISDAINSENGMLNTLRNEKSGKPSIPIYFSNQDLLWANPYKLNRF
                     GQGAFRLLVRRLYLELNGEPLQDYTLGKPTKLTYDFAHHVLIDWEKRLSGKIGQSVKQ
                     KLPLLGTKPSTSPFHAVFMVGDNPASDIIGAQNYGWNSCLVKTGVYNEGDDLKECKPT
                     LIVNDVFDAVTKTLEKYA"
     gene            complement(<574934..>575980)
                     /gene="DRE2"
                     /locus_tag="YKR071C"
                     /db_xref="GeneID:853945"
     mRNA            complement(<574934..>575980)
                     /gene="DRE2"
                     /locus_tag="YKR071C"
                     /product="Dre2p"
                     /transcript_id="NM_001179861.3"
                     /db_xref="GI:398365342"
                     /db_xref="GeneID:853945"
     CDS             complement(574934..575980)
                     /gene="DRE2"
                     /locus_tag="YKR071C"
                     /note="Component of the cytosolic Fe-S protein assembly
                     (CIA) machinery; contains an Fe-S cluster that receives
                     electrons from NADPH via the action of Tah18pin an early
                     step in the CIA pathway; ortholog of human Ciapin1;
                     protein abundance increases in response to DNA replication
                     stress"
                     /codon_start=1
                     /product="Dre2p"
                     /protein_id="NP_012997.3"
                     /db_xref="GI:398365343"
                     /db_xref="SGD:S000001779"
                     /db_xref="GeneID:853945"
                     /translation="MSQYKTGLLLIHPAVTTTPELVENTKAQAASKKVKFVDQFLINK
                     LNDGSITLENAKYETVHYLTPEAQTDIKFPKKLISVLADSLKPNGSLIGLSDIYKVDA
                     LINGFEIINEPDYCWIKMDSSKLNQTVSIPLKKKKTNNTKLQSGSKLPTFKKASSSTS
                     NLPSFKKADHSRQPIVKETDSFKPPSFKMTTEPKVYRVVDDLIEDSDDDDFSSDSSKA
                     QYFDQVDTSDDSIEEEELIDEDGSGKSMITMITCGKSKTKKKKACKDCTCGMKEQEEN
                     EINDIRSQQDKVVKFTEDELTEIDFTIDGKKVGGCGSCSLGDAFRCSGCPYLGLPAFK
                     PGQPINLDSISDDL"
     gene            complement(<576435..>578123)
                     /gene="SIS2"
                     /locus_tag="YKR072C"
                     /gene_synonym="HAL3"
                     /db_xref="GeneID:853946"
     mRNA            complement(<576435..>578123)
                     /gene="SIS2"
                     /locus_tag="YKR072C"
                     /gene_synonym="HAL3"
                     /product="phosphopantothenoylcysteine decarboxylase
                     complex subunit SIS2"
                     /transcript_id="NM_001179862.1"
                     /db_xref="GI:296146443"
                     /db_xref="GeneID:853946"
     CDS             complement(576435..578123)
                     /gene="SIS2"
                     /locus_tag="YKR072C"
                     /gene_synonym="HAL3"
                     /note="Negative regulatory subunit of protein phosphatase
                     1 (Ppz1p); involved in coenzyme A biosynthesis; subunit of
                     phosphopantothenoylcysteine decarboxylase (PPCDC: Cab3p,
                     Sis2p, Vhs3p) complex and the CoA-Synthesizing Protein
                     Complex (CoA-SPC: Cab2p, Cab3p, Cab4p, Cab5p, Sis2p and
                     Vhs3p); SIS2 has a paralog, VHS3, that arose from the
                     whole genome duplication"
                     /codon_start=1
                     /product="phosphopantothenoylcysteine decarboxylase
                     complex subunit SIS2"
                     /protein_id="NP_012998.1"
                     /db_xref="GI:6322925"
                     /db_xref="SGD:S000001780"
                     /db_xref="GeneID:853946"
                     /translation="MTAVASTSGKQDADHNQSIECPRFSRGQKEILLDHEDAKGKDSI
                     INSPVSGRQSISPTLSNATTTTTKSIMNATGTSGAVVSNTPEPGLKRVPAVTFSDLKQ
                     QQKQDSLTQLKNDSERTKSPNSNPAPVSNSIPGNHAVIPNHTNTSRTTQLSGSPLVNE
                     MKDYDPKKKDSALKIVDTMKPDKIMATSTPISRENNKVTAKAPTSITLRKEDAQDQAN
                     NVSGQINVRSTPEETPVKQSVIPSIIPKRENSKNLDPRLPQDDGKLHVLFGATGSLSV
                     FKIKPMIKKLEEIYGRDRISIQVILTQSATQFFEQRYTKKIIKSSEKLNKMSQYESTP
                     ATPVTPTPGQCNMAQVVELPPHIQLWTDQDEWDAWKQRTDPVLHIELRRWADILVVAP
                     LTANTLSKIALGLCDNLLTSVIRAWNPSYPILLAPSMVSSTFNSMMTKKQLQTIKEEM
                     SWVTVFKPSEKVMDINGDIGLGGMMDWNEIVNKIVMKLGGYPKNNEEEDDDEDEEEDD
                     DEEEDTEDKNENNNDDDDDDDDDDDDDDDDDDDDDDDDEDEDEAETPGIIDKHQ"
     gene            578965..579060
                     /locus_tag="tK(UUU)K"
                     /db_xref="GeneID:853948"
     tRNA            join(578965..579001,579025..579060)
                     /locus_tag="tK(UUU)K"
                     /product="tRNA-Lys"
                     /note="Lysine tRNA (tRNA-Lys), predicted by tRNAscan-SE
                     analysis; thiolation of uridine at wobble position (34)
                     requires Ncs6p"
                     /db_xref="SGD:S000006632"
                     /db_xref="GeneID:853948"
     gene            <579209..>579676
                     /gene="AIM29"
                     /locus_tag="YKR074W"
                     /db_xref="GeneID:853949"
     mRNA            <579209..>579676
                     /gene="AIM29"
                     /locus_tag="YKR074W"
                     /product="Aim29p"
                     /transcript_id="NM_001179864.3"
                     /db_xref="GI:398365360"
                     /db_xref="GeneID:853949"
     CDS             579209..579676
                     /gene="AIM29"
                     /locus_tag="YKR074W"
                     /note="hypothetical protein; epitope-tagged protein
                     localizes to the cytoplasm; YKR074W is not an essential
                     gene; null mutant displays elevated frequency of
                     mitochondrial genome loss"
                     /codon_start=1
                     /product="Aim29p"
                     /protein_id="NP_013000.3"
                     /db_xref="GI:398365361"
                     /db_xref="SGD:S000001782"
                     /db_xref="GeneID:853949"
                     /translation="MNSTKRLKMSTTFHDYDLEEPLTSNARPLKNSVITIRVIKSFPY
                     RNVKNIVLHDYDLADKTAKDLFNDVLNKIQNEGSFRPFRNVKFDTLKIYTHAHGSKTV
                     NLVINFDHDDDWTLDIENDKKKLFEYGIENETEISLFNKEDYLRFKENPEEKW"
     gene            complement(<579827..>580750)
                     /locus_tag="YKR075C"
                     /db_xref="GeneID:853950"
     mRNA            complement(<579827..>580750)
                     /locus_tag="YKR075C"
                     /product="hypothetical protein"
                     /transcript_id="NM_001179865.1"
                     /db_xref="GI:296146445"
                     /db_xref="GeneID:853950"
     CDS             complement(579827..580750)
                     /locus_tag="YKR075C"
                     /note="hypothetical protein; similar to Reg1p; expression
                     regulated by glucose and Rgt1p; GFP-fusion protein is
                     induced in response to the DNA-damaging agent MMS; YKR075C
                     has a paralog, YOR062C, that arose from the whole genome
                     duplication"
                     /codon_start=1
                     /product="hypothetical protein"
                     /protein_id="NP_013001.1"
                     /db_xref="GI:6322928"
                     /db_xref="SGD:S000001783"
                     /db_xref="GeneID:853950"
                     /translation="MTSLDDTIISYQNIMLLDNMTNYNKPAIDYFHHEFNDASLEISA
                     SWTLLLKMRKHKLLRLPSCSSEDVLDYNMYLVRLHHCLWRRWSINHYGLQNSKSNPLS
                     INWNKETDVTVLYGPDLTNIDSNENEISPVQNQIDQKQTKNLKSALKKNTECWVTEEV
                     DEINASIESNDNALVKLEDISCPSSVDSHTSSIFDQHSTCTKISSIDEDSEDLMNEKK
                     EQFPRKLKFNQAVMKREIDSKGTIRESLININDIQHSRHHRRHHRRHHHHHHQNSSHS
                     DETIKEAHYEFSNYTFGTMEEDIFYRNQVVF"
     rep_origin      581833..582070
                     /note="ARS1118;
                     Autonomously Replicating Sequence"
                     /db_xref="SGD:S000118408"
     gene            <582283..>583395
                     /gene="ECM4"
                     /locus_tag="YKR076W"
                     /gene_synonym="GTO2"
                     /db_xref="GeneID:853951"
     mRNA            <582283..>583395
                     /gene="ECM4"
                     /locus_tag="YKR076W"
                     /gene_synonym="GTO2"
                     /product="Ecm4p"
                     /transcript_id="NM_001179866.3"
                     /db_xref="GI:398365368"
                     /db_xref="GeneID:853951"
     CDS             582283..583395
                     /gene="ECM4"
                     /locus_tag="YKR076W"
                     /gene_synonym="GTO2"
                     /EC_number="1.8.5.1"
                     /EC_number="2.5.1.18"
                     /note="Omega class glutathione transferase; not essential;
                     similar to Ygr154cp; green fluorescent protein
                     (GFP)-fusion protein localizes to the cytoplasm"
                     /codon_start=1
                     /product="Ecm4p"
                     /protein_id="NP_013002.3"
                     /db_xref="GI:398365369"
                     /db_xref="SGD:S000001784"
                     /db_xref="GeneID:853951"
                     /translation="MSKQWASGTNGAFKRQVSSFRETISKQHPIYKPAKGRYWLYVSL
                     ACPWAHRTLITRALKGLTSVIGCSVVHWHLDEKGWRFLDMEKQLEDSEDFLEHWHDVA
                     GGIRTAKEDSSKSFAEIKNDSQRFMVDATNEPHYGYKRISDLYYKSDPQYSARFTVPV
                     LWDLETQTIVNNESSEIIRILNSSAFDEFVDDDHKKTDLVPAQLKTQIDDFNSWVYDS
                     INNGVYKTGFAEKAEVYESEVNNVFEHLDKVEKILSDKYSKLKAKYGEEDRQKILGEF
                     FTVGDQLTEADIRLYTTVIRFDPVYVQHFKCNFTSIRAGYPFIHLWVRNLYWNYDAFR
                     YTTDFDHIKLHYTRSHTRINPLGITPLGPKPDIRPL"
     gene            <583653..>584744
                     /gene="MSA2"
                     /locus_tag="YKR077W"
                     /db_xref="GeneID:853952"
     mRNA            <583653..>584744
                     /gene="MSA2"
                     /locus_tag="YKR077W"
                     /product="Msa2p"
                     /transcript_id="NM_001179867.1"
                     /db_xref="GI:296146447"
                     /db_xref="GeneID:853952"
     CDS             583653..584744
                     /gene="MSA2"
                     /locus_tag="YKR077W"
                     /note="Putative transcriptional activator; interacts with
                     G1-specific transcription factor MBF and G1-specific
                     promoters; MSA2 has a paralog, MSA1, that arose from the
                     whole genome duplication"
                     /codon_start=1
                     /product="Msa2p"
                     /protein_id="NP_013003.1"
                     /db_xref="GI:6322930"
                     /db_xref="SGD:S000001785"
                     /db_xref="GeneID:853952"
                     /translation="MVYTTPQQQQRFSSTPQSSHTLIFSPIRAPSMQTPSSLDYQSPS
                     IVVSSSSMKVHGRSSSFGKFSLSIGQNGKATILGPINVLPTDTSKMEKPVPKKKPVTS
                     DRVEKTRILSLLKKMRNKSSTVNKKYSKVPLKSTTSLQPAATAPSPLVSNIIKPSPKK
                     LASPRTPNANSNLNLNFTSFQIKTGFTPNLDGILLENFTSPNTTADSQGNSASNIINN
                     NHGSANNTNQFLFNLPLQSSPRQFRSPARLIDPLPISDWNTSLLMSPPRTTNFESANN
                     HFNSNFAQASMLRRPSLPHIDEVIPQDSNPANYSDRSDYLSVDQNANNHNGALSEQTY
                     NNIMKSSMISLPIEKDDATMALRKLVSRE"
     gene            <584952..>586709
                     /locus_tag="YKR078W"
                     /db_xref="GeneID:853953"
     mRNA            <584952..>586709
                     /locus_tag="YKR078W"
                     /product="hypothetical protein"
                     /transcript_id="NM_001179868.3"
                     /db_xref="GI:398365374"
                     /db_xref="GeneID:853953"
     CDS             584952..586709
                     /locus_tag="YKR078W"
                     /note="Cytoplasmic hypothetical protein; potential Cdc28p
                     substrate; contains a Phox homology (PX) domain and
                     specifically binds phosphatidylinositol 3-phosphate
                     (PtdIns-3-P); YKR078W has a paralog, VPS5, that arose from
                     the whole genome duplication"
                     /codon_start=1
                     /product="hypothetical protein"
                     /protein_id="NP_013004.3"
                     /db_xref="GI:398365375"
                     /db_xref="SGD:S000001786"
                     /db_xref="GeneID:853953"
                     /translation="MENDKASHASPSIGVNEFVVQGEISIDDSERSVKSVSVSISDDE
                     DSKTDVQDNMATPSTRSKFQTDLAIDNRLLEKDPKYKKLFTEKRRRRRPESCINLMTK
                     GKGTGQKDNINDQIFSLRILPGSDLNSLKDSLWIIKISTQPDVEKTIARAFSDFYWLY
                     HQLQNNHWGKTIPPPTRSNILVEKDEFAINHLFMIRNNEKYDPIFNFKPEYIISLQLM
                     AMIKHIFNDKVLRLDSNFIDFISWDDDLPESLQIVVDDSTFTGDKILMTSSQFRELKE
                     FHKQSKKVESITNSHASLIPVTELTEIYISPTKLFSRKDYQRLFQPQSTDNTFNNNDP
                     LIQEWIPKSKTLFTSLSFGSSAPTYQEASTEIQACHDWVSISKEQWKQLLYHVLQYIV
                     DEAVKVNSVINEFTECLKQISLDEVIRANSELFLKFSKLNESFLKKFKGASRQDILKL
                     IILFDENVRFCESFESILNQRLKLGKILSIIEVDLDKKKNFLDKLSPGNNNSNNEDLK
                     IRTAEDEYRIVLKRYNRVKQSWEKIMEDILNERKEFEKREAAEVNSCLKSIRDLNMDE
                     KKHYLQLWQDFVPDEHISQ"
     gene            complement(<586789..>589305)
                     /gene="TRZ1"
                     /locus_tag="YKR079C"
                     /db_xref="GeneID:853954"
     mRNA            complement(<586789..>589305)
                     /gene="TRZ1"
                     /locus_tag="YKR079C"
                     /product="Trz1p"
                     /transcript_id="NM_001179869.1"
                     /db_xref="GI:296146449"
                     /db_xref="GeneID:853954"
     CDS             complement(586789..589305)
                     /gene="TRZ1"
                     /locus_tag="YKR079C"
                     /EC_number="3.1.26.11"
                     /note="tRNA 3'-end processing endonuclease tRNase Z; also
                     localized to mitochondria and interacts genetically with
                     Rex2 exonuclease; homolog of the human candidate prostate
                     cancer susceptibility gene ELAC2"
                     /codon_start=1
                     /product="Trz1p"
                     /protein_id="NP_013005.1"
                     /db_xref="GI:6322932"
                     /db_xref="SGD:S000001787"
                     /db_xref="GeneID:853954"
                     /translation="MFTFIPITHPTSDTKHPLLLVQSAHGEKYFFGKIGEGSQRSLTE
                     NKIRISKLKDIFLTGELNWSDIGGLPGMILTIADQGKSNLVLHYGNDILNYIVSTWRY
                     FVFRFGIDLNDHIMKDKEVYKDKIIAVKSFNVLKNGGEDRLGVFDSFQKGVLRSIVAK
                     MFPKHAPTDRYDPSSDPHLNVELPDLDAKVEVSTNYEISFSPVRGKFKVEEAIKLGVP
                     KGPLFAKLTKGQTITLDNGIVVTPEQVLENERHFAKVLILDIPDDLYLNAFVEKFKDY
                     DCAELGMVYYFLGDEVTINDNLFAFIDIFEKNNYGKVNHMISHNKISPNTISFFGSAL
                     TTLKLKALQVNNYNLPKTDRVFSKDFYDRFDTPLSRGTSMCKSQEEPLNTIIEKDNIH
                     IFSQNKTVTFEPFRMNEEPMKCNINGEVADFSWQEIFEEHVKPLEFPLADVDTVINNQ
                     LHVDNFNNSAEKKKHVEIITLGTGSALPSKYRNVVSTLVKVPFTDADGNTINRNIMLD
                     AGENTLGTIHRMFSQLAVKSIFQDLKMIYLSHLHADHHLGIISVLNEWYKYNKDDETS
                     YIYVVTPWQYHKFVNEWLVLENKEILKRIKYISCEHFINDSFVRMQTQSVPLAEFNEI
                     LKENSNQESNRKLELDRDSSYRDVDLIRQMYEDLSIEYFQTCRAIHCDWAYSNSITFR
                     MDENNEHNTFKVSYSGDTRPNIEKFSLEIGYNSDLLIHEATLENQLLEDAVKKKHCTI
                     NEAIGVSNKMNARKLILTHFSQRYPKLPQLDNNIDVMAREFCFAFDSMIVDYEKIGEQ
                     QRIFPLLNKAFVEEKEEEEDVDDVESVQDLEVKLKKHKKN"
     gene            <590395..>591357
                     /gene="MTD1"
                     /locus_tag="YKR080W"
                     /db_xref="GeneID:853955"
     mRNA            <590395..>591357
                     /gene="MTD1"
                     /locus_tag="YKR080W"
                     /product="methylenetetrahydrofolate dehydrogenase
                     (NAD(+))"
                     /transcript_id="NM_001179870.3"
                     /db_xref="GI:398365386"
                     /db_xref="GeneID:853955"
     CDS             590395..591357
                     /gene="MTD1"
                     /locus_tag="YKR080W"
                     /EC_number="1.5.1.15"
                     /note="NAD-dependent 5,10-methylenetetrahydrafolate
                     dehydrogenase; plays a catalytic role in oxidation of
                     cytoplasmic one-carbon units; expression is regulated by
                     Bas1p and Bas2p, repressed by adenine, and may be induced
                     by inositol and choline"
                     /codon_start=1
                     /product="methylenetetrahydrofolate dehydrogenase
                     (NAD(+))"
                     /protein_id="NP_013006.3"
                     /db_xref="GI:398365387"
                     /db_xref="SGD:S000001788"
                     /db_xref="GeneID:853955"
                     /translation="MSKPGRTILASKVAETFNTEIINNVEEYKKTHNGQGPLLVGFLA
                     NNDPAAKMYATWTQKTSESMGFRYDLRVIEDKDFLEEAIIQANGDDSVNGIMVYFPVF
                     GNAQDQYLQQVVCKEKDVEGLNHVYYQNLYHNVRYLDKENRLKSILPCTPLAIVKILE
                     FLKIYNNLLPEGNRLYGKKCIVINRSEIVGRPLAALLANDGATVYSVDVNNIQKFTRG
                     ESLKLNKHHVEDLGEYSEDLLKKCSLDSDVVITGVPSENYKFPTEYIKEGAVCINFAC
                     TKNFSDDVKEKASLYVPMTGKVTIAMLLRNMLRLVRNVELSKEK"
     gene            complement(<591506..>592540)
                     /gene="RPF2"
                     /locus_tag="YKR081C"
                     /db_xref="GeneID:853956"
     mRNA            complement(<591506..>592540)
                     /gene="RPF2"
                     /locus_tag="YKR081C"
                     /product="Rpf2p"
                     /transcript_id="NM_001179871.1"
                     /db_xref="GI:296146451"
                     /db_xref="GeneID:853956"
     CDS             complement(591506..592540)
                     /gene="RPF2"
                     /locus_tag="YKR081C"
                     /note="Essential protein involved in rRNA maturation and
                     ribosomal assembly; involved in the processing of pre-rRNA
                     and the assembly of the 60S ribosomal subunit; interacts
                     with ribosomal protein L11; localizes predominantly to the
                     nucleolus; constituent of 66S pre-ribosomal particles"
                     /codon_start=1
                     /product="Rpf2p"
                     /protein_id="NP_013007.1"
                     /db_xref="GI:6322934"
                     /db_xref="SGD:S000001789"
                     /db_xref="GeneID:853956"
                     /translation="MIRTVKPKNARAKRALVKREAKLVENVKQALFIPGQSCNKNLHD
                     IMVDLSALKKPDMKRFNRKNDIHPFEDMSPLEFFSEKNDCSLMVLMTSSKKRKNNMTF
                     IRTFGYKIYDMIELMVADNFKLLSDFKKLTFTVGLKPMFTFQGAAFDTHPVYKQIKSL
                     FLDFFRGESTDLQDVAGLQHVISMTIQGDFQDGEPLPNVLFRVYKLKSYKSDQGGKRL
                     PRIELVEIGPRLDFKIGRIHTPSPDMVTEAHKKPKQLEMKTKKNVELDIMGDKLGRIH
                     MGKQDLGKLQTRKMKGLKSKFDQGTEEGDGEVDEDYEDEASYSDDGQEYEEEFVSATD
                     IEPSAKRQKK"
     gene            <592825..>596298
                     /gene="NUP133"
                     /locus_tag="YKR082W"
                     /gene_synonym="RAT3"
                     /db_xref="GeneID:853957"
     mRNA            <592825..>596298
                     /gene="NUP133"
                     /locus_tag="YKR082W"
                     /gene_synonym="RAT3"
                     /product="Nup133p"
                     /transcript_id="NM_001179872.3"
                     /db_xref="GI:398365402"
                     /db_xref="GeneID:853957"
     CDS             592825..596298
                     /gene="NUP133"
                     /locus_tag="YKR082W"
                     /gene_synonym="RAT3"
                     /note="Subunit of Nup84p subcomplex of nuclear pore
                     complex (NPC); contributes to nucleocytoplasmic transport,
                     NPC biogenesis; is involved in establishment of a normal
                     nucleocytoplasmic concentration gradient of GTPase Gsp1p;
                     also plays roles in several processes that may require
                     localization of genes or chromosomes at nuclear periphery,
                     including double-strand break repair, transcription and
                     chromatin silencing; relocalizes to cytosol in response to
                     hypoxia; homolog of human NUP133"
                     /codon_start=1
                     /product="Nup133p"
                     /protein_id="NP_013008.3"
                     /db_xref="GI:398365403"
                     /db_xref="SGD:S000001790"
                     /db_xref="GeneID:853957"
                     /translation="MSEKKVHLRLRKELSVPIAVVENESLAQLSYEEESQASLMDISM
                     EQQQLRLHSHFDNSKVFTENNRYIVKTLQTDYSSGFSNDDELNGYIDMQIGYGLVNDH
                     KKVYIWNIHSTQKDTPYITVPFRSDDNDEIAVAPRCILTFPATMDESPLALNPNDQDE
                     TGGLIIIKGSKAIYYEDINSINNLNFKLSEKFSHELELPINSSGGEKCDLMLNCEPAG
                     IVLSTNMGRIFFITIRNSMGKPQLKLGKLLNKPFKLGIWSKIFNTNSSVVSLRNGPIL
                     GKGTRLVYITTNKGIFQTWQLSATNSHPTKLIDVNIYEAILESLQDLYPFAHGTLKIW
                     DSHPLQDESSQLFLSSIYDSSCNETYYILSTIIFDSSSNSFTIFSTYRLNTFMESITD
                     TKFKPKIFIPQMENANDTNEVTSILVMFPNAVVITQVNSKLDSSYSMRRKWEDIVSLR
                     NDIDIIGSGYDSKSLYVLTKQMGVLQFFVKENEETNSKPEVGFVKSHVDQAVYFSKIN
                     ANPIDFNLPPEISLDQESIEHDLKLTSEEIFHSNGKYIPPMLNTLGQHLSVRKEFFQN
                     FLTFVAKNFNYKISPELKLDLIEKFEILNCCIKFNSIIRQSDVLNDIWEKTLSNYNLT
                     QNEHLTTKTVVINSPDVFPVIFKQFLNHVVFVLFPSQNQNFKLNVTNLINLCFYDGIL
                     EEGEKTIRYELLELDPMEVDTSKLPWFINFDYLNCINQCFFDFTFACEEEGSLDSYKE
                     GLLKIVKILYYQFNQFKIWINTQPVKSVNANDNFININNLYDDNHLDWNHVLCKVNLK
                     EQCIQIAEFYKDLSGLVQTLQTLDQNDSTTVSLYETFFNEFPKEFSFTLFEYLIKHKK
                     LNDLIFRFPQQHDVLIQFFQESAPKYGHVAWIQQILDGSYADAMNTLKNITVDDSKKG
                     ESLSECELHLNVAKLSSLLVEKDNLDINTLRKIQYNLDTIDAEKNISNKLKKGEVQIC
                     KRFKNGSIREVFNILVEELKSTTVVNLSDLVELYSMLDDEESLFIPLRLLSVDGNLLN
                     FEVKKFLNALVWRRIVLLNASNEGDKLLQHIVKRVFDEELPKNNDFPLPSVDLLCDKS
                     LLTPEYISETYGRFPIDQNAIREEIYEEISQVETLNSDNSLEIKLHSTIGSVAKEKNY
                     TINYETNTVEY"
     gene            complement(<596421..>596822)
                     /gene="DAD2"
                     /locus_tag="YKR083C"
                     /gene_synonym="HSK1"
                     /db_xref="GeneID:853958"
     mRNA            complement(<596421..>596822)
                     /gene="DAD2"
                     /locus_tag="YKR083C"
                     /gene_synonym="HSK1"
                     /product="Dad2p"
                     /transcript_id="NM_001179873.1"
                     /db_xref="GI:296146453"
                     /db_xref="GeneID:853958"
     CDS             complement(596421..596822)
                     /gene="DAD2"
                     /locus_tag="YKR083C"
                     /gene_synonym="HSK1"
                     /note="Essential subunit of the Dam1 complex (aka DASH
                     complex); complex couples kinetochores to the force
                     produced by MT depolymerization thereby aiding in
                     chromosome segregation; is transferred to the kinetochore
                     prior to mitosis"
                     /codon_start=1
                     /product="Dad2p"
                     /protein_id="NP_013009.1"
                     /db_xref="GI:6322936"
                     /db_xref="SGD:S000001791"
                     /db_xref="GeneID:853958"
                     /translation="MDSIDEQIAIKRKELQSLQKITSLTDGLKIQLTELNEQIKEMGM
                     NADSVAQLMNNWDSIINNISQASLGLLQYAEGDYEIGPWKDSKKKESEQSNETGLEAQ
                     ENDKNDEDNDEDEDLVPLPETMVRIRVDGNE"
     gene            complement(<597055..>598890)
                     /gene="HBS1"
                     /locus_tag="YKR084C"
                     /db_xref="GeneID:853959"
     mRNA            complement(<597055..>598890)
                     /gene="HBS1"
                     /locus_tag="YKR084C"
                     /product="ribosome dissociation factor GTPase HBS1"
                     /transcript_id="NM_001179874.3"
                     /db_xref="GI:398365408"
                     /db_xref="GeneID:853959"
     CDS             complement(597055..598890)
                     /gene="HBS1"
                     /locus_tag="YKR084C"
                     /note="GTPase with similarity to translation release
                     factors; together with binding partner Dom34p, facilitates
                     ribosomal subunit dissociation and peptidyl-tRNA release
                     when translation is stalled, particularly in 3' UTRs;
                     genetically implicated in mRNA no-go decay; HBS1 has a
                     paralog, SKI7, that arose from the whole genome
                     duplication"
                     /codon_start=1
                     /product="ribosome dissociation factor GTPase HBS1"
                     /protein_id="NP_013010.3"
                     /db_xref="GI:398365409"
                     /db_xref="SGD:S000001792"
                     /db_xref="GeneID:853959"
                     /translation="MAYSDYSDGADDMPDFHDEGEFDDYLNDDEYDLMNEVFPTLKAQ
                     LQDYQGWDNLSLKLALFDNNFDLESTLAELKKTLKKKKTPKKPIAAANGSANVTQKLA
                     NISISQQRPNDRLPDWLDEEESEGERNGEEANDEKTVQRYYKTTVPTKPKKPHDISAF
                     VKSALPHLSFVVLGHVDAGKSTLMGRLLYDLNIVNQSQLRKLQRESETMGKSSFKFAW
                     IMDQTNEERERGVTVSICTSHFSTHRANFTIVDAPGHRDFVPNAIMGISQADMAILCV
                     DCSTNAFESGFDLDGQTKEHMLLASSLGIHNLIIAMNKMDNVDWSQQRFEEIKSKLLP
                     YLVDIGFFEDNINWVPISGFSGEGVYKIEYTDEVRQWYNGPNLMSTLENAAFKISKEN
                     EGINKDDPFLFSVLEIIPSKKTSNDLALVSGKLESGSIQPGESLTIYPSEQSCIVDKI
                     QVGSQQGQSTNHEETDVAIKGDFVTLKLRKAYPEDIQNGDLAASVDYSSIHSAQCFVL
                     ELTTFDMNRPLLPGTPFILFIGVKEQPARIKRLISFIDKGNTASKKKIRHLGSKQRAF
                     VEIELIEVKRWIPLLTAHENDRLGRVVLRKDGRTIAAGKISEITQ"
     gene            complement(<599094..>599681)
                     /gene="MRPL20"
                     /locus_tag="YKR085C"
                     /db_xref="GeneID:853960"
     mRNA            complement(<599094..>599681)
                     /gene="MRPL20"
                     /locus_tag="YKR085C"
                     /product="mitochondrial 54S ribosomal protein YmL20"
                     /transcript_id="NM_001179875.1"
                     /db_xref="GI:296146455"
                     /db_xref="GeneID:853960"
     CDS             complement(599094..599681)
                     /gene="MRPL20"
                     /locus_tag="YKR085C"
                     /note="Mitochondrial ribosomal protein of the large
                     subunit"
                     /codon_start=1
                     /product="mitochondrial 54S ribosomal protein YmL20"
                     /protein_id="NP_013011.1"
                     /db_xref="GI:6322938"
                     /db_xref="SGD:S000001793"
                     /db_xref="GeneID:853960"
                     /translation="MIGRGVCCRSFHTAGSAWKQFGFPKTQVTTIYNKTKSASNYKGY
                     LKHRDAPGMYYQPSESIATGSVNSETIPRSFMAASDPRRGLDMPVQSTKAKQCPNVLV
                     GKSTVNGKTYHLGPQEIDEIRKLRLDNPQKYTRKFLAAKYGISPLFVSMVSKPSEQHV
                     QIMESRLQEIQSRWKEKRRIAREDRKRRKLLWYQA"
     gene            <599857..>603072
                     /gene="PRP16"
                     /locus_tag="YKR086W"
                     /gene_synonym="PRP23; RNA16"
                     /db_xref="GeneID:853961"
     mRNA            <599857..>603072
                     /gene="PRP16"
                     /locus_tag="YKR086W"
                     /gene_synonym="PRP23; RNA16"
                     /product="DEAH-box RNA helicase PRP16"
                     /transcript_id="NM_001179876.3"
                     /db_xref="GI:398365420"
                     /db_xref="GeneID:853961"
     CDS             599857..603072
                     /gene="PRP16"
                     /locus_tag="YKR086W"
                     /gene_synonym="PRP23; RNA16"
                     /EC_number="3.6.4.13"
                     /EC_number="3.6.1.-"
                     /note="DEAH-box RNA helicase involved in second catalytic
                     step of splicing and in exon ligation; exhibits
                     ATP-dependent RNA unwinding activity; mediates the release
                     of Yju2p and Cwc25p in the second step; in the absence of
                     ATP, stabilizes the binding of Cwc25p to the spliceosome
                     in the first catalytic step; missense mutation in human
                     ortholog DHX38 associated with early-onset retinitis
                     pigmentosa"
                     /codon_start=1
                     /product="DEAH-box RNA helicase PRP16"
                     /protein_id="NP_013012.3"
                     /db_xref="GI:398365421"
                     /db_xref="SGD:S000001794"
                     /db_xref="GeneID:853961"
                     /translation="MGHSGREERIKDIFKELTSKELTPGLLLTLQKLAQKPNTNLEQF
                     IASCKALTKLSSNNPIIFNELLELLKNKSEEDSTGPKKIAPSINKRKKFKIQLDLDDN
                     EDELDSPVQKKPAPTRTLFKRIDKLKAKQLRQYSPTVKDPSPNSEQQTQNGHAETKDY
                     EPTRSEVVEEDREWYDNDDDYGNLVPEPLSELPEEAKLLPVIRNIDNDDALRNTVQLY
                     PIPLKQRMEWIPPFLSKFALENKVPTSIIIGSISETSSQVSALSMVNPFRNPDSEFSA
                     NAKRGSKLVALRRINMEHIQQSRDNTTVLNTAMGEVLGLENNNKAKDKSNQKICDDTA
                     LFTPSKDDIKHTKEQLPVFRCRSQLLSLIRENQVVVIIGETGSGKTTQLAQYLYEEGY
                     ANDRGKSIVVTQPRRVAAISVAKRVAMEMQVPLGKEVGYSIRFEDVTDSECTKLKFVT
                     DGILLRETLLDDTLDKYSCVIIDEAHERSLNTDILLGFFKILLARRRDLKLIITSATM
                     NAKKFSAFFGNAPQFTIPGRTFPVQTIYTSNPVQDYVEAAVSQAVKIHLANDCSSGDI
                     LIFMTGQEDIETTFDTLQEKFLQVYSKKFGTANFEEINDIEILPIYSALPADLQFKIF
                     QDLHGTKRKIIIATNIAETSLTIKGIRYVIDCGYSKLKVYNPKIGLDSLVITPISKAN
                     ADQRSGRAGRTAPGTAYRLYTEDTFKEDMYLQTIPEIQRTNLSNTLLLLKSLDVTDEL
                     SKFPFIDKPPLQTFLSSLYELWFIGAIDTSGQLTPLGLQMAKFPLQPSLSKILLIAVR
                     NGCSDEMLTIVSMLSVPQVFYRPKERQKEADIARNKFFIAKSDHLTLLNVFEQWRANN
                     FSSHWCNKHFVQYKSLVRARDIRDQLLTILKSQKIPVISSGKDWDIIKKCICSGFAHQ
                     AAKITGLRNYVHLKTGVSVQLHPTSALHGLGDLPPYVVYHELLMTSKEYICCVTSVDP
                     FWLMEYGGLLYDIKRIKNDQEATTTGLFGEHYEHTLDKVEDDIDINIRRCKDMRDSVI
                     QELKMTDNSNKEDKKQKTKKQNILNGKENSMKPFKRRKPFF"
     gene            complement(<603195..>604232)
                     /gene="OMA1"
                     /locus_tag="YKR087C"
                     /db_xref="GeneID:853962"
     mRNA            complement(<603195..>604232)
                     /gene="OMA1"
                     /locus_tag="YKR087C"
                     /product="Oma1p"
                     /transcript_id="NM_001179877.1"
                     /db_xref="GI:296146457"
                     /db_xref="GeneID:853962"
     CDS             complement(603195..604232)
                     /gene="OMA1"
                     /locus_tag="YKR087C"
                     /EC_number="3.4.24.-"
                     /note="Metalloendopeptidase of the mitochondrial inner
                     membrane; important for adaptive responses to various
                     homeostatic insults and preservation of normal
                     mitochondrial function under damage-eliciting conditions;
                     involved in turnover of membrane-embedded proteins;
                     mediates degradation of Cox1p in coa2 mutant cells; member
                     of a family of predicted membrane-bound metallopeptidases
                     in prokaryotes and higher eukaryotes"
                     /codon_start=1
                     /product="Oma1p"
                     /protein_id="NP_013013.2"
                     /db_xref="GI:50593425"
                     /db_xref="SGD:S000001795"
                     /db_xref="GeneID:853962"
                     /translation="MLRNIIRFKGFGKGTSGGFLKPVSFRVQLTRCYRYDNGPSYRRF
                     NNGEYSQKSSFKSILLDKSSRKYLALLFGGCSLFYYTHLDKAPVSDRSRFIWVSRPLE
                     LTIGNYTYKSIWRQTQQEILPPQHPLSIKIENIFMKIVEAAYKDPSVDNSLLDGIKWE
                     IHVVNDPTASPNAFVLPGGKVFIFSSILPICANDDGIATVLAHEFAHQLARHTAENLS
                     KAPIYSLLGLVLYTVTGAHAINNILLDGFLRMPASRQMETEADYIGLMIMSRACFQPQ
                     ESIKVWERMANFEKQMNRGGVVNMEFLSTHPASTRRIENMSKWLPKANEIYEQSDCSS
                     MGNYYKSFFSM"
     gene            complement(<604405..>605418)
                     /gene="TVP38"
                     /locus_tag="YKR088C"
                     /db_xref="GeneID:853963"
     mRNA            complement(<604405..>605418)
                     /gene="TVP38"
                     /locus_tag="YKR088C"
                     /product="Tvp38p"
                     /transcript_id="NM_001179878.3"
                     /db_xref="GI:398365438"
                     /db_xref="GeneID:853963"
     CDS             complement(604405..605418)
                     /gene="TVP38"
                     /locus_tag="YKR088C"
                     /note="Integral membrane protein; localized to late Golgi
                     vesicles along with the v-SNARE Tlg2p; required for
                     asymmetric localization of Kar9p during mitosis;
                     GFP-fusion protein localizes to the cytoplasm in a
                     punctate pattern"
                     /codon_start=1
                     /product="Tvp38p"
                     /protein_id="NP_013014.3"
                     /db_xref="GI:398365439"
                     /db_xref="SGD:S000001796"
                     /db_xref="GeneID:853963"
                     /translation="MSQSYEAGNANMGQGEDDEFDGYFEDFDNDIMPNSNNGQRVGTN
                     AGLSFNDEVNVNDDDFLDIYNMSPRERLMHNIRKNVQKLQFYFYSLRLWQQIIIVLLG
                     IMLMIMGILLLVFHNAILHKVVVTSNDLREKMSTHFILMVLIFFVAFPPMIGYSLLST
                     TTGLIYGVSFEGWVTLALGSVTGSIASFVVFKTILHSRAEKLVHLNRRFEALASILQE
                     NNSYWILALLRLCPFPYSLTNGAIAGVYGISVRNFSIANIITTPKLFIYLFIGSRVKS
                     LAESESTGSRVFDLVSIIITLLILSLTAWLLYFKTKKRYLELQNRDRQVSTDQLPELS
                     FEV"
     gene            complement(<605633..>608365)
                     /gene="TGL4"
                     /locus_tag="YKR089C"
                     /gene_synonym="STC1"
                     /db_xref="GeneID:853964"
     mRNA            complement(<605633..>608365)
                     /gene="TGL4"
                     /locus_tag="YKR089C"
                     /gene_synonym="STC1"
                     /product="Tgl4p"
                     /transcript_id="NM_001179879.1"
                     /db_xref="GI:296146459"
                     /db_xref="GeneID:853964"
     CDS             complement(605633..608365)
                     /gene="TGL4"
                     /locus_tag="YKR089C"
                     /gene_synonym="STC1"
                     /EC_number="3.1.1.3"
                     /note="Multifunctional lipase/hydrolase/phospholipase;
                     triacylglycerol lipase, steryl ester hydrolase, and
                     Ca2+-independent phospholipase A2; catalyzes acyl-CoA
                     dependent acylation of LPA to PA; required with Tgl3p for
                     timely bud formation; phosphorylated and activated by
                     Cdc28p; TGL4 has a paralog, TGL5, that arose from the
                     whole genome duplication"
                     /codon_start=1
                     /product="Tgl4p"
                     /protein_id="NP_013015.1"
                     /db_xref="GI:6322942"
                     /db_xref="SGD:S000001797"
                     /db_xref="GeneID:853964"
                     /translation="MSSKISDLTSTQNKPLLVTQQLIEKYYEQILGTSQNIIPILNPK
                     NKFIRPSKDNSDVERVEEDAGKRLQTGKNKTTNKVNFNLDTGNEDKLDDDQETVTENE
                     NNDIEMVETDEGEDERQGSSLASKCKSFLYNVFVGNYERDILIDKVCSQKQHAMSFEE
                     WCSAGARLDDLTGKTEWKQKLESPLYDYKLIKDLTSRMREERLNRNYAQLLYIIRTNW
                     VRNLGNMGNVNLYRHSHVGTKYLIDEYMMESRLALESLMESDLDDSYLLGILQQTRRN
                     IGRTALVLSGGGTFGLFHIGVLGTLFELDLLPRVISGSSAGAIVASILSVHHKEEIPV
                     LLNHILDKEFNIFKDDKQKSESENLLIKISRFFKNGTWFDNKHLVNTMIEFLGDLTFR
                     EAYNRTGKILNITVSPASLFEQPRLLNNLTAPNVLIWSAVCASCSLPGIFPSSPLYEK
                     DPKTGERKPWTGSSSVKFVDGSVDNDLPISRLSEMFNVDHIIACQVNIHVFPFLKLSL
                     SCVGGEIEDEFSARLKQNLSSIYNFMANEAIHILEIGSEMGIAKNALTKLRSVLSQQY
                     SGDITILPDMCMLFRIKELLSNPTKEFLLREITNGAKATWPKVSIIQNHCGQEFALDK
                     AISYIKGRMIVTSSLKTPFQFADSVIGLIKAPEQTSDESKNPENSTLLTRTPTKGDNH
                     ISNVLDDNLLESESTNSLLLLRENASTYGRSPSGFRPRYSITSASLNPRHQRRKSDTI
                     STSRRPAKSFSFSVASPTSRMLRQSSKINGHPPPILQKKTSMGRLMFPMDAKTYDPES
                     HELIPHSASIETPAMVDKKLHFGRKSRYLRHMNKKWVSSSNILYTDSDKEDHPTLRLI
                     SNFDSDAMIHSDLAGNFRRHSIDGRPPSQATKSSPFRSRPSSSTQHKSTTSFTQ"
     gene            <608946..>611066
                     /gene="PXL1"
                     /locus_tag="YKR090W"
                     /db_xref="GeneID:853965"
     mRNA            <608946..>611066
                     /gene="PXL1"
                     /locus_tag="YKR090W"
                     /product="Pxl1p"
                     /transcript_id="NM_001179880.4"
                     /db_xref="GI:398365450"
                     /db_xref="GeneID:853965"
     CDS             608946..611066
                     /gene="PXL1"
                     /locus_tag="YKR090W"
                     /note="Protein that localizes to sites of polarized
                     growth; required for selection and/or maintenance of
                     polarized growth sites, may modulate signaling by the
                     GTPases Cdc42p and Rho1p; contains LIM domains and has
                     similarity to metazoan paxillin; relocalizes from bud neck
                     to cytoplasm upon DNA replication stress"
                     /codon_start=1
                     /product="Pxl1p"
                     /protein_id="NP_013016.4"
                     /db_xref="GI:398365451"
                     /db_xref="SGD:S000001798"
                     /db_xref="GeneID:853965"
                     /translation="MYNSIYGSPFPKINPKVRYKTALERAGFDTKPRNPFSSQRNAST
                     GSLQASVKSPPITRQRNVSAAPSVPVTMKSAYTASSKSAYSSVKGESDIYPPPVLENS
                     ERRSVTPPKNSNFTSSRPSDISRSISRPSERASQEDPFRFERDLDRQAEQYAASRHTC
                     KSPANKEFQAADNFPFNFEQEDAGNTEREQDLSPIERSFMMLTQNDTASVVNSMNQTD
                     NRGVLDQKLGKEQQKEESSIEYESEGQQEDENDIESLNFEPDPKLQMNLENEPLQDDF
                     PEAKQEEKNTEPKIPEINVTRESNTPSLTMNALDSKIYPDDNFSGLESSKEQKSPGVS
                     SSSTKVEDLSLDGLNEKRLSITSSENVETPYTATNLQVEQLIAQLDDVSLSRNAKLDM
                     NGNCLNAVDRKASRFKKSSAYLSGYPSMDIPVTQQTSIVQNSNTNLSRQTILVDKGDV
                     DEDAPSESTTNGGTPIFYKFKQSNVEYSNNEGMGSQETFRTKLPTIEALQLQHKRNIT
                     DLREEIDNSKSNDSHVLPNGGTTRYSSDADYKETEPIEFKYPPGEGPCRACGLEVTGK
                     RMFSKKENELSGQWHRECFKCIECGIKFNKHVPCYILGDEPYCQKHYHEENHSICKVC
                     SNFIEGECLENDKVERFHVDCLNCFLCKTAITNDYYIFNGEIPLCGNHDMEALLKEGI
                     DNATSSNDKNNTLSKRRTRLINFN"
     gene            <611525..>612265
                     /gene="SRL3"
                     /locus_tag="YKR091W"
                     /gene_synonym="WHI7"
                     /db_xref="GeneID:853966"
     mRNA            <611525..>612265
                     /gene="SRL3"
                     /locus_tag="YKR091W"
                     /gene_synonym="WHI7"
                     /product="DNA-binding protein SRL3"
                     /transcript_id="NM_001179881.1"
                     /db_xref="GI:296146461"
                     /db_xref="GeneID:853966"
     CDS             611525..612265
                     /gene="SRL3"
                     /locus_tag="YKR091W"
                     /gene_synonym="WHI7"
                     /note="GTB motif (G1/S transcription factor binding)
                     containing protein; binds SBF-regulated promoters in
                     hydroxyurea-treated cells; when overexpressed, suppresses
                     the lethality of a rad53 null mutation; potential Cdc28p
                     substrate; SRL3 has a paralog, WHI5, that arose from the
                     whole genome duplication"
                     /codon_start=1
                     /product="DNA-binding protein SRL3"
                     /protein_id="NP_013017.2"
                     /db_xref="GI:50593426"
                     /db_xref="SGD:S000001799"
                     /db_xref="GeneID:853966"
                     /translation="MFLKTPNWETVNETPKSRVLTINELISPNLDTESNSLLATPARK
                     YFKTSISEAQDSPTSAPSPDGNEDPTYQYNVQFHFPGPITPTTPRSKNAEMFPSPTPP
                     LVSPTAVIEEENDDSVREFSRTLKSRLNCAMVKLSKEHEQVALIPPPPTEKIRKGSYS
                     NKFAAKHRRCHSLDESKKFLSSLEDSSAHAAFLKAISSKHAKSNRVDNVNVSPLRWSS
                     HRRTQSTQENSLQEVVAIDTLLKMSSSD"
     rep_origin      612378..612463
                     /note="ARS1120;
                     Autonomously Replicating Sequence"
                     /db_xref="SGD:S000118409"
     gene            complement(<612665..>613885)
                     /gene="SRP40"
                     /locus_tag="YKR092C"
                     /db_xref="GeneID:853967"
     mRNA            complement(<612665..>613885)
                     /gene="SRP40"
                     /locus_tag="YKR092C"
                     /product="Srp40p"
                     /transcript_id="NM_001179882.3"
                     /db_xref="GI:398365460"
                     /db_xref="GeneID:853967"
     CDS             complement(612665..613885)
                     /gene="SRP40"
                     /locus_tag="YKR092C"
                     /note="Nucleolar serine-rich protein; role in preribosome
                     assembly or transport; may function as a chaperone of
                     small nucleolar ribonucleoprotein particles (snoRNPs);
                     immunologically and structurally to rat Nopp140"
                     /codon_start=1
                     /product="Srp40p"
                     /protein_id="NP_013018.3"
                     /db_xref="GI:398365461"
                     /db_xref="SGD:S000001800"
                     /db_xref="GeneID:853967"
                     /translation="MASKKIKVDEVPKLSVKEKEIEEKSSSSSSSSSSSSSSSSSSSS
                     SSSSSGESSSSSSSSSSSSSSDSSDSSDSESSSSSSSSSSSSSSSSDSESSSESDSSS
                     SGSSSSSSSSSDESSSESESEDETKKRARESDNEDAKETKKAKTEPESSSSSESSSSG
                     SSSSSESESGSESDSDSSSSSSSSSDSESDSESDSQSSSSSSSSDSSSDSDSSSSDSS
                     SDSDSSSSSSSSSSDSDSDSDSSSDSDSSGSSDSSSSSDSSSDESTSSDSSDSDSDSD
                     SGSSSELETKEATADESKAEETPASSNESTPSASSSSSANKLNIPAGTDEIKEGQRKH
                     FSRVDRSKINFEAWELTDNTYKGAAGTWGEKANEKLGRVRGKDFTKNKNKMKRGSYRG
                     GSITLESGSYKFQD"
     gene            <615730..>617535
                     /gene="PTR2"
                     /locus_tag="YKR093W"
                     /db_xref="GeneID:853968"
     mRNA            <615730..>617535
                     /gene="PTR2"
                     /locus_tag="YKR093W"
                     /product="Ptr2p"
                     /transcript_id="NM_001179883.1"
                     /db_xref="GI:296146463"
                     /db_xref="GeneID:853968"
     CDS             615730..617535
                     /gene="PTR2"
                     /locus_tag="YKR093W"
                     /note="Integral membrane peptide transporter; mediates
                     transport of di- and tri-peptides; conserved protein that
                     contains 12 transmembrane domains; PTR2 expression is
                     regulated by the N-end rule pathway via repression by
                     Cup9p"
                     /codon_start=1
                     /product="Ptr2p"
                     /protein_id="NP_013019.1"
                     /db_xref="GI:6322946"
                     /db_xref="SGD:S000001801"
                     /db_xref="GeneID:853968"
                     /translation="MLNHPSQGSDDAQDEKQGDFPVIEEEKTQAVTLKDSYVSDDVAN
                     STERYNLSPSPEDEDFEGPTEEEMQTLRHVGGKIPMRCWLIAIVELSERFSYYGLSAP
                     FQNYMEYGPNDSPKGVLSLNSQGATGLSYFFQFWCYVTPVFGGYVADTFWGKYNTICC
                     GTAIYIAGIFILFITSIPSVGNRDSAIGGFIAAIILIGIATGMIKANLSVLIADQLPK
                     RKPSIKVLKSGERVIVDSNITLQNVFMFFYFMINVGSLSLMATTELEYHKGFWAAYLL
                     PFCFFWIAVVTLIFGKKQYIQRPIGDKVIAKSFKVCWILTKNKFDFNAAKPSVHPEKN
                     YPWNDKFVDEIKRALAACKVFIFYPIYWTQYGTMISSFITQASMMELHGIPNDFLQAF
                     DSIALIIFIPIFEKFVYPFIRRYTPLKPITKIFFGFMFGSFAMTWAAVLQSFVYKAGP
                     WYNEPLGHNTPNHVHVCWQIPAYVLISFSEIFASITGLEYAYSKAPASMKSFIMSIFL
                     LTNAFGSAIGCALSPVTVDPKFTWLFTGLAVACFISGCLFWLCFRKYNDTEEEMNAMD
                     YEEEDEFDLNPISAPKANDIEILEPMESLRSTTKY"
     gene            complement(<617996..>618750)
                     /gene="RPL40B"
                     /locus_tag="YKR094C"
                     /gene_synonym="CEP52B; UB12; UBI2"
                     /db_xref="GeneID:853969"
     mRNA            complement(join(<617996..618374,618743..>618750))
                     /gene="RPL40B"
                     /locus_tag="YKR094C"
                     /gene_synonym="CEP52B; UB12; UBI2"
                     /product="ubiquitin-ribosomal 60S subunit protein L40B
                     fusion protein"
                     /transcript_id="NM_001179884.3"
                     /db_xref="GI:398365468"
                     /db_xref="GeneID:853969"
     CDS             complement(join(617996..618374,618743..618750))
                     /gene="RPL40B"
                     /locus_tag="YKR094C"
                     /gene_synonym="CEP52B; UB12; UBI2"
                     /note="Ubiquitin-ribosomal 60S subunit protein L40B fusion
                     protein; cleaved to yield ubiquitin and ribosomal protein
                     L40B; ubiquitin may facilitate assembly of the ribosomal
                     protein into ribosomes; homologous to mammalian ribosomal
                     protein L40, no bacterial homolog; RPL40B has a paralog,
                     RPL40A, that arose from the whole genome duplication"
                     /codon_start=1
                     /product="ubiquitin-ribosomal 60S subunit protein L40B
                     fusion protein"
                     /protein_id="NP_013020.3"
                     /db_xref="GI:398365469"
                     /db_xref="SGD:S000001802"
                     /db_xref="GeneID:853969"
                     /translation="MQIFVKTLTGKTITLEVESSDTIDNVKSKIQDKEGIPPDQQRLI
                     FAGKQLEDGRTLSDYNIQKESTLHLVLRLRGGIIEPSLKALASKYNCDKSVCRKCYAR
                     LPPRATNCRKRKCGHTNQLRPKKKLK"
     gene            <619805..>625432
                     /gene="MLP1"
                     /locus_tag="YKR095W"
                     /gene_synonym="MPL1"
                     /db_xref="GeneID:853970"
     mRNA            <619805..>625432
                     /gene="MLP1"
                     /locus_tag="YKR095W"
                     /gene_synonym="MPL1"
                     /product="Mlp1p"
                     /transcript_id="NM_001179885.1"
                     /db_xref="GI:296146465"
                     /db_xref="GeneID:853970"
     CDS             619805..625432
                     /gene="MLP1"
                     /locus_tag="YKR095W"
                     /gene_synonym="MPL1"
                     /note="Myosin-like protein associated with the nuclear
                     envelope; nuclear basket protein that connects the nuclear
                     pore complex with the nuclear interior; involved with
                     Tel1p in telomere length control; involved with Pml1p and
                     Pml39p in nuclear retention of unspliced mRNAs; MLP1 has a
                     paralog, MLP2, that arose from the whole genome
                     duplication"
                     /codon_start=1
                     /product="Mlp1p"
                     /protein_id="NP_013021.1"
                     /db_xref="GI:6322948"
                     /db_xref="SGD:S000001803"
                     /db_xref="GeneID:853970"
                     /translation="MSDHDTPMESIQNGENSDERLNAIASFFGCSLEQVKSFDGDVVK
                     HLNDKLLQFNELKSENLKVTVSFDELKASSLKKIDGLKTEMENVIRENDKIRKERNDT
                     FVKFESVENEKMKLSSELEFVKRKLDDLTEEKKETQSNQQRTLKILDERLKEIELVRV
                     ENNRSNSECKKLRSTIMDLETKQQGYITNDLNSRTELERKTQELTLLQSNNDWLEKEL
                     RSKNEQYLSYRQKTDKVILDIRNELNRLRNDFQMERTNNDVLKQKNNELSKSLQEKLL
                     EIKGLSDSLNSEKQEFSAEMSLKQRLVDLLESQLNAVKEELNSIRELNTAKVIADDSK
                     KQTPENEDLLKELQLTKEKLAQCEKECLRLSSITDEADEDNENLSAKSSSDFIFLKKQ
                     LIKERRTKEHLQNQIETFIVELEHKVPIINSFKERTDMLENELNNAALLLEHTSNEKN
                     AKVKELNAKNQKLVECENDLQTLTKQRLDLCRQIQYLLITNSVSNDSKGPLRKEEIQF
                     IQNIMQEDDSTITESDSQKVVTERLVEFKNIIQLQEKNAELLKVVRNLADKLESKEKK
                     SKQSLQKIESETVNEAKEAIITLKSEKMDLESRIEELQKELEELKTSVPNEDASYSNV
                     TIKQLTETKRDLESQVQDLQTRISQITRESTENMSLLNKEIQDLYDSKSDISIKLGKE
                     KSSRILAEERFKLLSNTLDLTKAENDQLRKRFDYLQNTILKQDSKTHETLNEYVSCKS
                     KLSIVETELLNLKEEQKLRVHLEKNLKQELNKLSPEKDSLRIMVTQLQTLQKEREDLL
                     EETRKSCQKKIDELEDALSELKKETSQKDHHIKQLEEDNNSNIEWYQNKIEALKKDYE
                     SVITSVDSKQTDIEKLQYKVKSLEKEIEEDKIRLHTYNVMDETINDDSLRKELEKSKI
                     NLTDAYSQIKEYKDLYETTSQSLQQTNSKLDESFKDFTNQIKNLTDEKTSLEDKISLL
                     KEQMFNLNNELDLQKKGMEKEKADFKKRISILQNNNKEVEAVKSEYESKLSKIQNDLD
                     QQTIYANTAQNNYEQELQKHADVSKTISELREQLHTYKGQVKTLNLSRDQLENALKEN
                     EKSWSSQKESLLEQLDLSNSRIEDLSSQNKLLYDQIQIYTAADKEVNNSTNGPGLNNI
                     LITLRRERDILDTKVTVAERDAKMLRQKISLMDVELQDARTKLDNSRVEKENHSSIIQ
                     QHDDIMEKLNQLNLLRESNITLRNELENNNNKKKELQSELDKLKQNVAPIESELTALK
                     YSMQEKEQELKLAKEEVHRWKKRSQDILEKHEQLSSSDYEKLESEIENLKEELENKER
                     QGAEAEEKFNRLRRQAQERLKTSKLSQDSLTEQVNSLRDAKNVLENSLSEANARIEEL
                     QNAKVAQGNNQLEAIRKLQEDAEKASRELQAKLEESTTSYESTINGLNEEITTLKEEI
                     EKQRQIQQQLQATSANEQNDLSNIVESMKKSFEEDKIKFIKEKTQEVNEKILEAQERL
                     NQPSNINMEEIKKKWESEHEQEVSQKIREAEEALKKRIRLPTEEKINKIIERKKEELE
                     KEFEEKVEERIKSMEQSGEIDVVLRKQLEAKVQEKQKELENEYNKKLQEELKDVPHSS
                     HISDDERDKLRAEIESRLREEFNNELQAIKKKSFDEGKQQAMMKTTLLERKLAKMESQ
                     LSETKQSAESPPKSVNNVQNPLLGLPRKIEENSNSPFNPLLSGEKLLKLNSKSSSGGF
                     NPFTSPSPNKHLQNDNDKRESLANKTDPPTHLEPSFNIPASRGLISSSSTLSTDTNDE
                     ELTSNNPAQKDSSNRNVQSEEDTEKKKEGEPVKRGEAIEEQTKSNKRPIDEVGELKND
                     EDDTTENINESKKIKTEDEEEKETDKVNDENSI"
     gene            <625864..>626205
                     /gene="PCC1"
                     /locus_tag="YKR095W-A"
                     /db_xref="GeneID:1500489"
     mRNA            join(<625864..625901,625977..>626205)
                     /gene="PCC1"
                     /locus_tag="YKR095W-A"
                     /product="Pcc1p"
                     /transcript_id="NM_001184522.3"
                     /db_xref="GI:398365492"
                     /db_xref="GeneID:1500489"
     CDS             join(625864..625901,625977..626205)
                     /gene="PCC1"
                     /locus_tag="YKR095W-A"
                     /note="Component of the EKC/KEOPS protein complex;
                     EKC/KEOPS complex is required for t6A tRNA modification
                     and telomeric TG1-3 recombination; may have role in
                     transcription; other complex members are Kae1p, Gon7p,
                     Bud32p, and Cgi121p"
                     /codon_start=1
                     /product="Pcc1p"
                     /protein_id="NP_878113.4"
                     /db_xref="GI:398365493"
                     /db_xref="SGD:S000028512"
                     /db_xref="GeneID:1500489"
                     /translation="MTSKREKSLDHTLELKIPFETERQATIATKVLSPDPILKPQDFQ
                     VDYSSEKNVMLVQFRSIDDRVLRVGVSSIIDSIKTIVEAMDVLS"
     gene            <626793..>630380
                     /gene="ESL2"
                     /locus_tag="YKR096W"
                     /db_xref="GeneID:853971"
     mRNA            <626793..>630380
                     /gene="ESL2"
                     /locus_tag="YKR096W"
                     /product="Esl2p"
                     /transcript_id="NM_001179886.1"
                     /db_xref="GI:296146467"
                     /db_xref="GeneID:853971"
     CDS             626793..630380
                     /gene="ESL2"
                     /locus_tag="YKR096W"
                     /note="hypothetical protein; interacts with Pex14p; may
                     interact with ribosomes, based on co-purification
                     experiments; green fluorescent protein (GFP)-fusion
                     protein localizes to the nucleus and cytoplasm; predicted
                     to contain a PINc domain; ESL2 has a paralog, ESL1, that
                     arose from the whole genome duplication"
                     /codon_start=1
                     /product="Esl2p"
                     /protein_id="NP_013022.1"
                     /db_xref="GI:6322949"
                     /db_xref="SGD:S000001804"
                     /db_xref="GeneID:853971"
                     /translation="MPETSVQNPLRLSENENTRSMFLSASQQQRPSATPSFPRLVRNT
                     TANLSLSDFQVLNPSSKRQNSNSVYDDINSSKRRISRPRFSDIEGKNNDHTYPERTTV
                     KESEKNPSPRYVSSSKRALKRENSVGITQSSALISKSFSENGGSIAHEKWSPENMIKP
                     LNVSQNSLAFVDAGSDEQSKSEIVGGFQRKSNNSQEINDKDNSARDQDFNNSGNNNNN
                     NNHSSNNNDNNNNNNDDNNNNNNSNSRDNNNNSDDSNEREENDSCKPASNKRSGIALI
                     QKLQELYKVIVKQEIELQERCSQLTNSQTTELKSLWTIYKINTDLVNNYVTFITTALL
                     PSQPPHDLVIGQEIVEIYRIERRLWVYGTITFLDVLKNFSNFMDPEVCCQFITHVFVS
                     LSTMISDIPSKYSITWLQRLGDLSRMAIALYPSSFIDWKLSAEHWYTEAMKYIYNHGK
                     LYYHMSTVQQNTLEAFVNLGKSVFCQETFTPSPQYMQLVIDNIYQRAFVERNNGNLRN
                     SLLIEYLKHSEAMLLPSFLESPDLQNVVLSYFIEKFGIDANGCNIFNAEDMFVQNPDF
                     FKYFFRHGPSFAQSHILQIVGFGEPKNPFAILFELPKYLKERKDKKERKKSSNNDSSV
                     TESSTGNSRNDNEDDDEIMSSTTSISDHDLLAEFFNDIDTLRRPILPSMLTNEAWLET
                     LKFLNMTSLKCGIIVLRKFLHGPLGIALPHILPWIYFIISICLKSSQLSDPVSKEFWM
                     IIVKRAFPWDTMVTFMNVLIVYLLDNQTSNSIIGDLCDDYDKLSLSELLELFNEGEEL
                     PEILGCWGTLWFDTICEKNTHSISSEDNFQEIGIKDYMALDSPTDGIIFDEKDENGEK
                     FWKRACRTIFLFRELSRSFPIGVIIRNDPLIYRSSFQNTNILGSLVFKLEPLCNIHNN
                     IPVLGALESIIDISEARSENNTDLHAVPELSVNEGDNIFHYVGYKKLRADYTCFDKNG
                     EFLSASLYTTWYVPNSNNTNIEDNINYNSEKENEGLFLECIKSDYPEIDFKTTYFVFD
                     ATSWLRHSARIFKLAQNRLLRFAICLTTFQELRFLRKSKDENVMEAATRGIITIRQLY
                     YENKVLPLRFTGNVATHIEENLEFEEQITWRTHVDEFVIESVMKAQEKLESASEPRLS
                     PRRFNYVVLISDDDAMKKKAEEKEIKTLSTRFVFSLCTKLGEQRHLCTD"
     gene            <631152..>632801
                     /gene="PCK1"
                     /locus_tag="YKR097W"
                     /gene_synonym="JPM2; PPC1"
                     /db_xref="GeneID:853972"
     mRNA            <631152..>632801
                     /gene="PCK1"
                     /locus_tag="YKR097W"
                     /gene_synonym="JPM2; PPC1"
                     /product="phosphoenolpyruvate carboxykinase PCK1"
                     /transcript_id="NM_001179887.3"
                     /db_xref="GI:398365504"
                     /db_xref="GeneID:853972"
     CDS             631152..632801
                     /gene="PCK1"
                     /locus_tag="YKR097W"
                     /gene_synonym="JPM2; PPC1"
                     /EC_number="4.1.1.49"
                     /note="Phosphoenolpyruvate carboxykinase; key enzyme in
                     gluconeogenesis, catalyzes early reaction in carbohydrate
                     biosynthesis, glucose represses transcription and
                     accelerates mRNA degradation, regulated by Mcm1p and
                     Cat8p, located in the cytosol"
                     /codon_start=1
                     /product="phosphoenolpyruvate carboxykinase PCK1"
                     /protein_id="NP_013023.3"
                     /db_xref="GI:398365505"
                     /db_xref="SGD:S000001805"
                     /db_xref="GeneID:853972"
                     /translation="MSPSKMNATVGSTSEVEQKIRQELALSDEVTTIRRNAPAAVLYE
                     DGLKENKTVISSSGALIAYSGVKTGRSPKDKRIVEEPTSKDEIWWGPVNKPCSERTWS
                     INRERAADYLRTRDHIYIVDAFAGWDPKYRIKVRVVCARAYHALFMTNMLIRPTEEEL
                     AHFGEPDFTVWNAGQFPANLHTQDMSSKSTIEINFKAMEMIILGTEYAGEMKKGIFTV
                     MFYLMPVHHNVLTLHSSANQGIQNGDVTLFFGLSGTGKTTLSADPHRLLIGDDEHCWS
                     DHGVFNIEGGCYAKCINLSAEKEPEIFDAIKFGSVLENVIYDEKSHVVDYDDSSITEN
                     TRCAYPIDYIPSAKIPCLADSHPKNIILLTCDASGVLPPVSKLTPEQVMYHFISGYTS
                     KMAGTEQGVTEPEPTFSSCFGQPFLALHPIRYATMLATKMSQHKANAYLINTGWTGSS
                     YVSGGKRCPLKYTRAILDSIHDGSLANETYETLPIFNLQVPTKVNGVPAELLNPAKNW
                     SQGESKYRGAVTNLANLFVQNFKIYQDRATPDVLAAGPQFE"
     gene            complement(<633026..>635179)
                     /gene="UBP11"
                     /locus_tag="YKR098C"
                     /db_xref="GeneID:853973"
     mRNA            complement(<633026..>635179)
                     /gene="UBP11"
                     /locus_tag="YKR098C"
                     /product="Ubp11p"
                     /transcript_id="NM_001179888.1"
                     /db_xref="GI:296146469"
                     /db_xref="GeneID:853973"
     CDS             complement(633026..635179)
                     /gene="UBP11"
                     /locus_tag="YKR098C"
                     /EC_number="3.4.19.12"
                     /note="Ubiquitin-specific protease; cleaves ubiquitin from
                     ubiquitinated proteins; UBP11 has a paralog, UBP7, that
                     arose from the whole genome duplication"
                     /codon_start=1
                     /product="Ubp11p"
                     /protein_id="NP_013024.1"
                     /db_xref="GI:6322951"
                     /db_xref="SGD:S000001806"
                     /db_xref="GeneID:853973"
                     /translation="MLLNPDQILNLVRKVYEVDIKQFYSQLRLKNLRGLLDHAAHLFN
                     VYLRDLEINQEMEALTAFIIGCYYLYLIIPQSLQFQTRNNLYSSYAKLKNDYQDEHVM
                     GYVLKVVRDESTVIVDRYLAESNGICRTIKRKRAYSLPLRPLPVHMASLSIHNKFDGS
                     LHEIPNELTKPTNDNSKEDIVRESNQIASSNKLEAGSEVAYYTSKEALSKPSYLKLST
                     GKDALFKTLSSPATAPPVHSLEVSSQIRDSSQDSSSSLSKVEKPKEEEGKIEAIESSA
                     PKAYNLPVIEDSNDLLSELSITGLQNPCNTCYINSIIQCLFGTTLFRDLFLTKKYRLF
                     LNTNKYPKEVQLSRSIYVLFKKMYLNGGRAIIPNRFLKMCKKLRPDLNIPDDQQDTQE
                     FLLIVLARIHEELSNENVVKYYPDLVSYDANALQVNPSKYEKWYERNVITDGLSPIDH
                     IYRGQLENILKCQRCGNSSYSYSTFYVLSLAIPKLSLYSFTSKSRKIKLEDCINLFTG
                     DEELSGDNAWDCPNCRITDSKSKKEEITSQKKKSTIFGFHSRSRSKSPHHHHHHHHSS
                     DDSTKNAKKRNSKKLTTIKSLDFIVLPPILVIHLSRFYYDLTKKNSTVITYPLILNII
                     LKNGKVIRYKLYGTVNHSGNLINGHYTSVVNKEKSHEIGLNRQVWVTFDDDYIQQHRK
                     DRNNFEAGKTEMSSDEVYVLFYERMDEENYEEEFC"
     gene            <635851..>638286
                     /gene="BAS1"
                     /locus_tag="YKR099W"
                     /db_xref="GeneID:853974"
     mRNA            <635851..>638286
                     /gene="BAS1"
                     /locus_tag="YKR099W"
                     /product="Bas1p"
                     /transcript_id="NM_001179889.3"
                     /db_xref="GI:398365512"
                     /db_xref="GeneID:853974"
     CDS             635851..638286
                     /gene="BAS1"
                     /locus_tag="YKR099W"
                     /note="Myb-related transcription factor; involved in
                     regulating basal and induced expression of genes of the
                     purine and histidine biosynthesis pathways; also involved
                     in regulation of meiotic recombination at specific genes"
                     /codon_start=1
                     /product="Bas1p"
                     /protein_id="NP_013025.3"
                     /db_xref="GI:398365513"
                     /db_xref="SGD:S000001807"
                     /db_xref="GeneID:853974"
                     /translation="MSNISTKDIRKSKPKRGSGFDLLEVTESLGYQTHRKNGRNSWSK
                     DDDNMLRSLVNESAKELGYENGLEDVKTIQQSNHLSKCIAWDVLATRFKHTVRTSKDV
                     RKRWTGSLDPNLKKGKWTQEEDEQLLKAYEEHGPHWLSISMDIPGRTEDQCAKRYIEV
                     LGPGSKGRLREWTLEEDLNLISKVKAYGTKWRKISSEMEFRPSLTCRNRWRKIITMVV
                     RGQASEVITKAIKENKNIDMTDGKLRQHPIADSDIRSDSTPNKEEQLQLSQQNNPSLI
                     KQDILNVKENESSKLPRLKDNDGPILNDSKPQALPPLKEISAPPPIRMTQVGQTHTSG
                     SIRSKVSLPIEGLSQMNKQSPGGISDSPQTSLPPAFNPASLDEHMMNSNSISDSPKHA
                     YSTVKTREPNSSSTQWKFTLKDGQGLSISNGTIDSTKLVKELVDQAKKYSLKISIHQH
                     IHNHYVTSTDHPVSSNTGLSNIGNINGNPLLMDSFPHMGRQLGNGLPGLNSNSDTFNP
                     EYRTSLDNMDSDFLSRTPNYNAFSLEATSHNPADNANELGSQSNRETNSPSVFYPQAN
                     TLIPTNSTATNNEIIQGNVSANSMSPNFNGTNGKAPSSTASYTTSGSEMPPDVGPNRI
                     AHFNYLPPTIRPHLGSSDATRGADLNKLLNPSPNSVRSNGSKTKKKEKRKSESSQHHS
                     SSSVTTNKFNHIDQSEISRTTSRSDTPLRDEDGLDFWETLRSLATTNPNPPVEKSAEN
                     DGAKPQVVHQGIGSHTEDSSLGSHSGGYDFFNELLDKKADTLHNEAKKTSEHDMTSGG
                     STDNGSVLPLNPS"
     gene            complement(<638901..>639968)
                     /gene="SKG1"
                     /locus_tag="YKR100C"
                     /gene_synonym="YKR099C-A"
                     /db_xref="GeneID:853975"
     mRNA            complement(<638901..>639968)
                     /gene="SKG1"
                     /locus_tag="YKR100C"
                     /gene_synonym="YKR099C-A"
                     /product="Skg1p"
                     /transcript_id="NM_001179890.1"
                     /db_xref="GI:296146471"
                     /db_xref="GeneID:853975"
     CDS             complement(638901..639968)
                     /gene="SKG1"
                     /locus_tag="YKR100C"
                     /gene_synonym="YKR099C-A"
                     /note="Transmembrane protein with a role in cell wall
                     polymer composition; localizes on inner surface of plasma
                     membrane at bud and in daughter cell; SKG1 has a paralog,
                     AIM20, that arose from the whole genome duplication"
                     /codon_start=1
                     /product="Skg1p"
                     /protein_id="NP_013026.2"
                     /db_xref="GI:42759863"
                     /db_xref="SGD:S000001808"
                     /db_xref="GeneID:853975"
                     /translation="MTASTSVAVGCAVGIPVGVGIIIAVCFWFNLQKRYKREEQDDRE
                     LERAIYDESGFVSFDNFGPLRDSKDEAALASSELKNPDHTSGSSEGSAHPEEKDGKSR
                     DQEKPLGKKNSKYYVPAYRRKINLLQVRNNNYGNNARQKSVVDLPSINNSSNVSLSSS
                     QRHITKRQISVYDQMVPVISDEGPNFFADPSSDTNTSNDQNKASMIELKHNTRQSSNE
                     NLIRNLQNQDFGSYYPRRASSSFLNGNISNASFHTRNSSITSVNKRDALEDVFATPKS
                     AAQSQLPNTFDKDNEGMDADHSVKDSRSAITDKDKDLYKLQNNYDVGNIGEIAEEDQY
                     ENEFTNYSQSKREFIESLRPK"
     gene            <640540..>642504
                     /gene="SIR1"
                     /locus_tag="YKR101W"
                     /db_xref="GeneID:853976"
     mRNA            <640540..>642504
                     /gene="SIR1"
                     /locus_tag="YKR101W"
                     /product="Sir1p"
                     /transcript_id="NM_001179891.3"
                     /db_xref="GI:398365528"
                     /db_xref="GeneID:853976"
     CDS             640540..642504
                     /gene="SIR1"
                     /locus_tag="YKR101W"
                     /note="Protein involved in silencing at mating-type loci
                     HML and HMR; recruitment to silent chromatin requires
                     interactions with Orc1p and with Sir4p, through a common
                     Sir1p domain; binds to centromeric chromatin"
                     /codon_start=1
                     /product="Sir1p"
                     /protein_id="NP_013027.4"
                     /db_xref="GI:398365529"
                     /db_xref="SGD:S000001809"
                     /db_xref="GeneID:853976"
                     /translation="MLQINSRLAVIDGWLVDTVKRKPINFRSPEVRLLLPNDDDYKKL
                     SQQNLVDWTRLKKDSNSVLVGVKSMELFKHIKLVLREFFLLEDGRIILKRIRSKLRYK
                     VVKKLTCKCCRLYLPKWGTVYIHPMLKDKEKPLAGVCEFSLDVNPDREYPLIEINVSH
                     QYIIIEGFLLYLNERRLYRWNDNNLRSQVGLTKWAHLRKTYNPVSLDILYSLNSNFYF
                     VKDDLLFQLLGKRVFVKFCKVMENGKCGKAPLWYRVKRTTTAKATHIAYAISNSTAPD
                     SFKSKNNDYRFIVREKPIVENTISNLDYSDIKKQQFTEAEVVKRKISADISQIENVHT
                     QFNSQKEKNNIRVNKVSSEVLDQISKFPVSRVTLLLMSAGQDKNYIELVEELARRLEK
                     ICIEKTTQSLEEIRDTFQANPEMQASFDKEYYQSIEEYKITLELIKEDLLITLIKQME
                     NMWAAEKKFSTEEEYVSPRFLVADGFLIDLAEEKPINPKDPRLLTLLKDHQRAMIDQM
                     NLVKWNDFKKYQDPIPLKAKTLFKFCKQIKKKFLRGADFKLHTLPTEANLKYEPERMT
                     VLCSCVPILLDDQTVQYLYDDSIIPEFEATSSYATKQSKCGRKMSLQMEPDLLFQEAI
                     RRMRHLTAYDVLRRNYIAAFEELYMGNCND"
     rep_origin      642727..642973
                     /note="ARS1123;
                     Autonomously Replicating Sequence"
                     /db_xref="SGD:S000118410"
     gene            <646356..>649865
                     /gene="FLO10"
                     /locus_tag="YKR102W"
                     /db_xref="GeneID:853977"
     mRNA            <646356..>649865
                     /gene="FLO10"
                     /locus_tag="YKR102W"
                     /product="Flo10p"
                     /transcript_id="NM_001179892.1"
                     /db_xref="GI:296146473"
                     /db_xref="GeneID:853977"
     CDS             646356..649865
                     /gene="FLO10"
                     /locus_tag="YKR102W"
                     /note="Member of the FLO family of cell wall flocculation
                     proteins; not expressed in most lab strains;
                     overproduction induces flocculation that can be inhibited
                     by mannose, sucrose, or glucose; overproduction also
                     promotes haploid invasive growth and diploid filamentous
                     growth"
                     /codon_start=1
                     /product="Flo10p"
                     /protein_id="NP_013028.1"
                     /db_xref="GI:6322955"
                     /db_xref="SGD:S000001810"
                     /db_xref="GeneID:853977"
                     /translation="MPVAARYIFLTGLFLLSVANVALGTTEACLPAGEKKNGMTINFY
                     QYSLKDSSTYSNPSYMAYGYADAEKLGSVSGQTKLSIDYSIPCNGASDTCACSDDDAT
                     EYSASQVVPVKRGVKLCSDNTTLSSKTEKRENDDCDQGAAYWSSDLFGFYTTPTNVTV
                     EMTGYFLPPKTGTYTFGFATVDDSAILSVGGNVAFECCKQEQPPITSTDFTINGIKPW
                     NADAPTDIKGSTYMYAGYYYPIKIVYSNAVSWGTLPVSVVLPDGTEVNDDFEGYVFSF
                     DDNATQAHCSVPNPAEHARTCVSSATSSWSSSEVCTECTETESTSYVTPYVTSSSWSS
                     SEVCTECTETESTSTSTPYVTSSSSSSSEVCTECTETESTSYVTPYVSSSTAAANYTS
                     SFSSSSEVCTECTETESTSTSTPYVTSSSWSSSEVCTECTETESTSYVTPYVSSSTAA
                     ANYTSSFSSSSEVCTECTETESTSTSTPYVTSSSSSSSEVCTECTETESTSYVTPYVS
                     SSTAAANYTSSFSSSSEVCTECTETESTSTSTPYVTSSSWSSSEVCTECTETESTSYV
                     TPYVSSSTAAANYTSSFSSSSEVCTECTETESTSTSTPYATSSTGTATSFTASTSNTM
                     TSLVQTDTTVSFSLSSTVSEHTNAPTSSVESNASTFISSNKGSVKSYVTSSIHSITPM
                     YPSNQTVTSSSVVSTPITSESSESSASVTILPSTITSEFKPSTMKTKVVSISSSPTNL
                     ITSYDTTSKDSTVGSSTSSVSLISSISLPSSYSASSEQIFHSSIVSSNGQALTSFSST
                     KVSSSESSESHRTSPTTSSESGIKSSGVEIESTSTSSFSFHETSTASTSVQISSQFVT
                     PSSPISTVAPRSTGLNSQTESTNSSKETMSSENSASVMPSSSATSPKTGKVTSDETSS
                     GFSRDRTTVYRMTSETPSTNEQTTLITVSSCESNSCSNTVSSAVVSTATTTINGITTE
                     YTTWCPLSATELTTVSKLESEEKTTLITVTSCESGVCSETASPAIVSTATATVNDVVT
                     VYSTWSPQATNKLAVSSDIENSASKASFVSEAAETKSISRNNNFVPTSGTTSIETHTT
                     TTSNASENSDNVSASEAVSSKSVTNPVLISVSQQPRGTPASSMIGSSTASLEMSSYLG
                     IANHLLTNSGISIFIASLLLAIV"
     gene            <653080..>656736
                     /gene="NFT1"
                     /locus_tag="YKR103W"
                     /db_xref="GeneID:853978"
     mRNA            <653080..>656736
                     /gene="NFT1"
                     /locus_tag="YKR103W"
                     /product="putative multidrug transporter NFT1"
                     /transcript_id="NM_001179893.3"
                     /db_xref="GI:398365538"
                     /db_xref="GeneID:853978"
     CDS             653080..656736
                     /gene="NFT1"
                     /locus_tag="YKR103W"
                     /note="Putative transporter of the MRP subfamily; adjacent
                     ORFs YKR103W and YKR104W are merged in different strain
                     backgrounds; MRP stands for multidrug
                     resistance-associated protein"
                     /codon_start=1
                     /product="putative multidrug transporter NFT1"
                     /protein_id="NP_013029.3"
                     /db_xref="GI:398365539"
                     /db_xref="SGD:S000001811"
                     /db_xref="GeneID:853978"
                     /translation="MIKNGTCPYWERDDLSECARREYIEFKFPLFILLTGMIYAFCKV
                     FRAFYLRGKNHTNEAPEFEEQGNGNHEYARFSVLRLKSAWESRSFCNVNNRSTFDKFK
                     KFIEGAFIVLQLTIHLYILSSMPMDNKKFFHQGFLVQMFLWILLLVVITLRLISASQS
                     FRWVLACKRDLWAVSFYSYASLFTLSILPLRSVFIGKIKDKIMVKYIISETFIDLALL
                     LLLSTSSIEGTRYSFLVENENKKLPPAPTVFGLLTFSRIDRLIWKAYKHCLGNADIWD
                     LDINNKSIAILANFEMSSKKGRLLPNIICYFKAVFISQLFLAFVSSFLNFVPSLLMPR
                     ILSYVNDPKSKSWNLVSLYVSSMLVSKIIATTCRGQGLFLGEKGTMQLRTVLISNIYS
                     KTLRRTILKDSTTSLQKNASTSFEENPDSSEAEPRKKSSRKDNSVNNVMSIDAFKVSE
                     AMNTFYLACEAVFMTVTALMILYSLLGWSAFAGTFALLAMIPLNFWCATFYGNYQADQ
                     LILTDKRTSGISEALNSIRVIKLLAWENLFYQKIINVRDGEIRLLKKKATIFFLNHLI
                     WFFGPTLVSAITFSVFIKFQNQTLTPTIAFTALSLFAILRTPMDQIASTVSLLIQSFI
                     SLERIQDYLNESETRKYEILEQSNTKFGFEDASMEWEAAETSFKLKNISIDFKLNSLN
                     AIIGPTGSGKSSLLLGLLGELNLLSGKIYVPTVESRDDLEIGKDGMTNSMAYCSQTPW
                     LISGTIKDNVVFGEIFNKQKFDDVMKSCCLDKDIKAMTAGIRTDVGDGGFSLSGGQQQ
                     RIALARAIYSSSRYLILDDCLSAVDPETALYIYEECLCGPMMKGRTCIITSHNISLVT
                     KRADWLVILDRGEVKSQGKPSDLIKSNEFLRESINNDSKNTTHNQIDLKRSTTSKKTK
                     NGDPEGGNSQDEVCAEVENFEETKMEGSVKFSAYKWLADYFGGLGVVFVFTSSSILIH
                     GITLSQGFWLRYWLDTGSSGSKSTWLYRIVEGHSNIYFLLTYIIIGLVSSFLTSGKVW
                     IAIISGTNVTKKIFAKLLSSILYAKLRFHNVTPTGRIMNRFSKDMDIIDQQLIPNFEG
                     LSYSVVVCLWIILLIGYVTPQFLLFAIPLCALYYTVCTLYLRASRELKRIDNINISPI
                     HQLFAEAIKGVTTIRALADERRFITQSLVAIDRSNAPFFYLNMATEWITYRVDIIGTL
                     VLFSSSVMIIMKAS"
     gene            <656836..>657756
                     /locus_tag="YKR104W"
                     /gene_synonym="NFT1"
                     /db_xref="GeneID:853979"
     mRNA            <656836..>657756
                     /locus_tag="YKR104W"
                     /gene_synonym="NFT1"
                     /product="hypothetical protein"
                     /transcript_id="NM_001179894.1"
                     /db_xref="GI:296146475"
                     /db_xref="GeneID:853979"
     CDS             656836..657756
                     /locus_tag="YKR104W"
                     /gene_synonym="NFT1"
                     /note="Putative transporter of the MRP subfamily; contains
                     a stop codon in S288C; adjacent ORFs YKR103W and YKR104W
                     are merged in different strain backgrounds; MRP stands for
                     multidrug resistance-associated protein"
                     /codon_start=1
                     /product="hypothetical protein"
                     /protein_id="NP_013030.1"
                     /db_xref="GI:6322957"
                     /db_xref="SGD:S000001812"
                     /db_xref="GeneID:853979"
                     /translation="MSSVERIKEYTDIPSESNGYISPPANWPQTGDVELKNLSLRYSP
                     HSSKALDNVSFKVKAGTKVGIVGRTGAGKSSIIAAIYRLSDWENGTITIDNKDIKHIP
                     LERLRNSISCIPQDPTLFDGTVRSNLDPFDRYSDVQIYGVLSKVGLIEECDELCLIFE
                     QEQPNFSSHKLRNRFIDLNTVVKSGGSNLSQGQRQLLCLARSMLGARNIMLIDEATAS
                     IDYISDAKIQKTIRETMKNTTILTIAHRLRSVIDYDKILVMEMGRVKEYDHPYTLISD
                     RNTIFYRLCRQSGEFENLFELAKVSFDNKR"
     gene            complement(<658716..>660464)
                     /gene="VBA5"
                     /locus_tag="YKR105C"
                     /db_xref="GeneID:853980"
     mRNA            complement(<658716..>660464)
                     /gene="VBA5"
                     /locus_tag="YKR105C"
                     /product="Vba5p"
                     /transcript_id="NM_001179895.3"
                     /db_xref="GI:398365554"
                     /db_xref="GeneID:853980"
     CDS             complement(658716..660464)
                     /gene="VBA5"
                     /locus_tag="YKR105C"
                     /note="Plasma membrane protein of the Major Facilitator
                     Superfamily (MFS); involved in amino acid uptake and drug
                     sensitivity; VBA5 has a paralog, VBA3, that arose from a
                     segmental duplication"
                     /codon_start=1
                     /product="Vba5p"
                     /protein_id="NP_013031.3"
                     /db_xref="GI:398365555"
                     /db_xref="SGD:S000001813"
                     /db_xref="GeneID:853980"
                     /translation="MEETKYSSQQEIEGACGSDASLNARGSNDSPMGLSLYLCLASLT
                     LVLFITALDILIVGTIIDVVAEQFGNYSKTGWLVTGYSLPNAILSLIWGRFASIIGFQ
                     HSLILAILIFEAGSLIAALASSMNMLIFGRVVAGVGGSGLQTLCFVIGCTMVGERSRP
                     LVISILSCAFAVAAIVGPIIGGAFTTHVTWRWCFYINLPIGGLAIIMFLLTYKAENKG
                     ILQQIKDAIGTISSFTFSKFRHQVNFKRLMNGIIFKFDFFGFALCSAGLVLFLLGLTF
                     GGNKYSWNSGQVITYLVLGVLLFIFSLVYDFFLFDKFNPEPDNISYRPLLLRRLVAKP
                     AIIIVNMVTFLLCTGYNGQMIYSVQFFQLIFASSAWKAGLHLIPIVITNVIAAIASGV
                     ITKKLGLVKPLLIFGGVLGVIGAGLMTLMTNTSTKSTQIGVLLLPGFSLGFALQASLM
                     SAQLQITKDRPEAAMDFIEVTAFNTFMKSLGTTLGGVLSTTVFSASFHNKVSRAHLEP
                     YEGKTVDDMILYRLQNYDGSHSTIGNILSDSIKNVFWMDLGFYALGFLFCSFSSNKKL
                     IIPKKDDTPEDNLEDK"
     gene            <661442..>663289
                     /gene="GEX2"
                     /locus_tag="YKR106W"
                     /db_xref="GeneID:853981"
     mRNA            <661442..>663289
                     /gene="GEX2"
                     /locus_tag="YKR106W"
                     /product="Gex2p"
                     /transcript_id="NM_001179896.1"
                     /db_xref="GI:296146477"
                     /db_xref="GeneID:853981"
     CDS             661442..663289
                     /gene="GEX2"
                     /locus_tag="YKR106W"
                     /note="Proton:glutathione antiporter; localized to the
                     vacuolar and plasma membranes; expressed at a very low
                     level; potential role in resistance to oxidative stress
                     and modulation of the PKA pathway; GEX2 has a paralog,
                     GEX1, that arose from a segmental duplication"
                     /codon_start=1
                     /product="Gex2p"
                     /protein_id="NP_013032.1"
                     /db_xref="GI:6322959"
                     /db_xref="SGD:S000001814"
                     /db_xref="GeneID:853981"
                     /translation="MSSSVVGASSNKKSGIRQSCEIIERERHSNDDTYSMTSTFFKLK
                     ENEIMSAQFDSLKYKILLISTAFVCGFGISLDYTLRSTYTGYATNSYSEHSLLSTVQV
                     INAVVSVGSQVVYSRLSDHFGRLRLFLVATIFYIMGTIIQSQATRLTMYAAGSVFYNC
                     GYVGTNLLLTLILSDFSSLKWRMFYQYASYWPYIIIPWISGNIITAANPQKNWSWNIA
                     MWAFIYPLSTLPIIFLILYMKYKSSKTAEWRSLKEQARKERTGGLFENLVFLFWKLDI
                     VGILLITVSLGCILVPLTLANETSQKWHNSKIIATLVSGGCLFFIFLYWEAKFAKSPL
                     LPFKLLSDRGIWAPLGVTFFNFFTFFISCDYLYPVLLVSMKESSTSAARIVNLPDFVA
                     ATASPFYSLLVAKTRKLKLSVIGGCAAWMVCMGLFYKYRGGSGSHEGVIAASVIMGLS
                     GLLCSNSVIVILQAMTTHSRMAVITGIQYTFSKLGAAIGASVSGAIWTQTMPNQLYKN
                     LGNDTLAEIAYASPYTFISDYPWGSPERDAVVESYRYVQRIIMTVGLACTVPFFTFTM
                     FMRNPELIDKATHEEFTEDGLVVLPDEENIFSQIKALFRHNRSNKKSGC"
     LTR             665430..665668
                     /note="Ty5 LTR"
                     /db_xref="SGD:S000007063"
     telomere        665904..666816
                     /note="TEL11R; Telomeric region on the right arm of
                     Chromosome XI; composed of an X element core sequence, X
                     element combinatorial repeats, and a terminal stretch of
                     telomeric repeats"
                     /db_xref="SGD:S000028978"
CONTIG      join(BK006944.2:1..666816)
//
DBGET integrated database retrieval system