LOCUS NC_001144 1078177 bp DNA linear PLN 25-FEB-2013
DEFINITION Saccharomyces cerevisiae S288c chromosome XII, complete sequence.
ACCESSION NC_001144
VERSION NC_001144.5 GI:330443681
DBLINK Project: 128
KEYWORDS TPA:inferential.
SOURCE Saccharomyces cerevisiae S288c
ORGANISM Saccharomyces cerevisiae S288c
Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina;
Saccharomycetes; Saccharomycetales; Saccharomycetaceae;
Saccharomyces.
REFERENCE 1 (bases 1 to 1078177)
AUTHORS Johnston,M., Hillier,L., Riles,L., Albermann,K., Andre,B.,
Ansorge,W., Benes,V., Bruckner,M., Delius,H., Dubois,E.,
Dusterhoft,A., Entian,K.D., Floeth,M., Goffeau,A., Hebling,U.,
Heumann,K., Heuss-Neitzel,D., Hilbert,H., Hilger,F., Kleine,K.,
Kotter,P., Louis,E.J., Messenguy,F., Mewes,H.W., Hoheisel,J.D. et
al.
TITLE The nucleotide sequence of Saccharomyces cerevisiae chromosome XII
JOURNAL Nature 387 (6632 SUPPL), 87-90 (1997)
PUBMED 9169871
REFERENCE 2 (bases 1 to 1078177)
AUTHORS Goffeau,A., Barrell,B.G., Bussey,H., Davis,R.W., Dujon,B.,
Feldmann,H., Galibert,F., Hoheisel,J.D., Jacq,C., Johnston,M.,
Louis,E.J., Mewes,H.W., Murakami,Y., Philippsen,P., Tettelin,H. and
Oliver,S.G.
TITLE Life with 6000 genes
JOURNAL Science 274 (5287), 546 (1996)
PUBMED 8849441
REFERENCE 3 (bases 1 to 1078177)
CONSRTM NCBI Genome Project
TITLE Direct Submission
JOURNAL Submitted (14-FEB-2013) National Center for Biotechnology
Information, NIH, Bethesda, MD 20894, USA
REFERENCE 4 (bases 1 to 1078177)
CONSRTM Saccharomyces Genome Database
TITLE Direct Submission
JOURNAL Submitted (06-FEB-2013) Department of Genetics, Stanford
University, Stanford, CA, USA
REMARK Protein update by submitter
REFERENCE 5 (bases 1 to 1078177)
CONSRTM Saccharomyces Genome Database
TITLE Direct Submission
JOURNAL Submitted (04-MAY-2012) Department of Genetics, Stanford
University, Stanford, CA, USA
REMARK Protein update by submitter
REFERENCE 6 (bases 1 to 1078177)
CONSRTM Saccharomyces Genome Database
TITLE Direct Submission
JOURNAL Submitted (31-MAR-2011) Department of Genetics, Stanford
University, Stanford, CA, USA
REMARK Sequence update by submitter
REFERENCE 7 (bases 1 to 1078177)
CONSRTM Saccharomyces Genome Database
TITLE Direct Submission
JOURNAL Submitted (14-DEC-2009) Department of Genetics, Stanford
University, Stanford, CA, USA
COMMENT PROVISIONAL REFSEQ: This record has not yet been subject to final
NCBI review. The reference sequence is identical to BK006945.
On Apr 26, 2011 this sequence version replaced gi:85666119.
Sequence assembly version R64-1-1.
COMPLETENESS: full length.
PRIMARY REFSEQ_SPAN PRIMARY_IDENTIFIER PRIMARY_SPAN COMP
1-6119 Z73172.1 1-6119
3011-11725 Z73171.1 1-8715
9837-13082 Z73170.1 1-3246
9837-13082 Z73170.1 1-3246
12048-14647 Z73169.1 1-2600
13446-16638 Z73168.1 1-3193
16073-17955 Z73167.1 1-1883
17614-21137 Z73166.1 1-3524
19708-22473 Z73165.1 1-2766
21840-23568 Z73164.1 1-1729
22981-25755 Z73163.1 1-2775
25297-27408 Z73162.1 1-2112
26995-30108 Z73161.1 1-3114
28306-32893 Z73160.1 1-4588
31705-35502 Z73159.1 1-3797
35205-37332 Z73158.1 1-2128
36362-39803 Z73156.1 1-3442
39472-40665 Z73155.1 1-1194
40415-41279 Z73154.1 1-865
41206-46671 Z73153.1 1-5466
46266-47858 Z73152.1 1-1593
47464-49937 Z73150.1 1-2474
48663-52086 Z73148.1 1-3424
51948-53130 Z73147.1 1-1183
52591-54210 Z73146.1 1-1620
53932-64061 Z73145.1 1-10130
59566-65774 Z73144.1 1-6209
65208-66561 Z73143.1 1-1354
66519-68579 Z73142.1 1-2061
68257-70632 Z73140.1 1-2376
70479-73408 Z73139.1 1-2930
73147-74269 Z73138.1 1-1123
74102-77151 Z73137.1 1-3050
76748-80355 Z73136.1 1-3608
80206-81460 Z73135.1 1-1255
80698-84803 Z73134.1 1-4106
83711-87402 Z73133.1 1-3692
86565-88622 Z73132.1 1-2058
88156-94746 Z73131.1 1-6591
90866-95565 Z73130.1 1-4700
95122-97996 Z73129.1 1-2875
97486-99043 Z73128.1 1-1558
98837-100946 Z73127.1 1-2110
100202-105555 Z73126.1 1-5354
105348-109901 Z73125.1 1-4554
106173-112233 Z73123.1 1-6061
111333-112846 Z73122.1 1-1514
112546-116431 Z73121.1 1-3886
115994-121321 Z73120.1 1-5328
121112-122074 Z73119.1 1-963
121649-125533 Z73118.1 1-3885
122409-127522 Z73117.1 1-5114
127256-129329 Z73116.1 1-2074
128993-131204 Z73115.1 1-2212
130614-131728 Z73114.1 1-1115
131415-134301 Z73113.1 1-2887
133988-136585 Z73112.1 1-2598
136263-137939 Z73111.1 1-1677
137867-141072 Z73110.1 1-3206
140547-143200 Z73109.1 1-2654
142924-146290 Z73108.1 1-3367
146042-147889 Z73107.1 1-1848
147602-151388 Z73106.1 1-3787
150164-154342 Z73173.1 1-4179
153978-156854 Z73174.1 1-2877
156335-157933 Z73175.1 1-1599
157731-160048 Z73176.1 1-2318
159506-161754 Z73177.1 1-2249
161435-164391 Z73178.1 1-2957
163894-165576 Z73179.1 1-1683
165403-166536 Z73180.1 1-1134
166084-167319 Z73181.1 1-1236
167137-169102 Z73182.1 1-1966
167803-169981 Z73183.1 1-2179
169679-171338 Z73184.1 1-1660
170351-172267 Z73185.1 1-1917
171765-175226 Z73186.1 1-3462
174983-176801 Z73187.1 1-1819
176745-177607 Z73188.1 1-863
177417-178706 Z73189.1 1-1290
178622-180287 Z73190.1 1-1666
179100-181788 Z73191.1 1-2689
181482-183622 Z73192.1 1-2141
183406-184173 Z73193.1 1-768
184163-185497 Z73194.1 1-1335
184927-187662 Z73195.1 1-2738
187130-194451 Z73196.1 1-7324
193282-195449 Z73197.1 1-2168
195175-196828 Z73198.1 1-1654
196473-199649 Z73199.1 1-3177
198128-201975 Z73200.1 1-3848
201316-203289 Z73201.1 1-1974
202591-204224 Z73202.1 1-1634
204082-204990 Z73203.1 1-909
204786-208760 Z73204.1 1-3975
208501-210511 Z73205.1 1-2011
210270-212368 Z73206.1 1-2099
211934-221520 Z73207.1 1-9587
214457-222684 Z73208.1 1-8228
222133-224920 Z73209.1 1-2788
223060-225425 Z73210.1 1-2366
225173-228907 Z73211.1 1-3735
228597-229965 Z73212.1 1-1369
229698-231701 Z73214.1 1-2004
230452-232389 Z73215.1 1-1938
232014-235036 Z73216.1 1-3023
233665-238000 Z73217.1 1-4336
237704-239346 Z73218.1 1-1643
238814-242231 Z73219.1 1-3418
241408-243885 Z73220.1 1-2478
243353-245586 Z73221.1 1-2234
245173-246323 Z73222.1 1-1151
246073-247200 Z73223.1 1-1128
246978-248099 Z73224.1 1-1122
247954-248716 Z73225.1 1-763
248427-251271 Z73226.1 1-2845
250256-253860 Z73227.1 1-3605
253081-255305 Z73228.1 1-2225
254959-257991 Z73229.1 1-3033
257358-259737 Z73230.1 1-2380
259402-260978 Z73231.1 1-1577
260548-263193 Z73232.1 1-2646
262767-264156 Z73233.1 1-1390
263955-265455 Z73235.1 1-1501
265255-266372 Z73236.1 1-1118
266278-267168 Z73237.1 1-891
266919-267812 Z73238.1 1-894
267724-271007 Z73239.1 1-3284
269058-271629 Z73240.1 1-2572
271464-274140 Z73241.1 1-2677
273916-275377 Z73242.1 1-1462
275212-278861 Z73243.1 1-3650
278627-281018 Z73244.1 1-2392
280944-281955 Z73245.1 1-1012
281622-282926 Z73246.1 1-1305
282457-283871 Z73247.1 1-1415
283608-285735 Z73249.1 1-2128
284276-326297 U53880.1 1-42022
325098-365437 U53876.1 1-40340
343768-346584 Z73275.1 1-2817
346585-364937 "ATGA...ATTT" 1-18353
364938-380630 U53878.1 1-15693
371211-374943 Z73285.1 1-3733
374944-379430 "TCAT...GATT" 1-4487
379431-402653 U53877.1 1-23223
400654-429807 U53881.1 1-29154
429608-468929 U53879.1 1-39322
447576-460166 Z73326.1 1-12591
460167-468810 "GTAG...ACTA" 1-8644
468811-498236 U51921.1 1-29427
497837-538574 U17246.1 1-40738
538375-577244 U14913.2 1-38870
576245-617698 U19027.1 1-41454
617299-657753 U20865.1 1-40455
654754-687247 U17244.1 1-32494
686048-700874 U17245.1 1-14827
699875-740088 U17243.1 1-40214
738089-757286 U17247.1 1-19198
754987-792716 U20618.2 1-37728
792517-830058 U19028.1 1-37541
829459-844633 U19102.1 1-15175
844234-876039 U19103.1 1-31806
875040-897799 U19104.1 1-22761
897400-937600 U19729.2 1-40198
936801-964950 U20162.1 1-28149
964551-1000355 U20939.1 1-35805
997856-1022616 U21094.1 1-24761
1022417-1044147 U22382.1 1-21732
1043948-1073581 U22383.1 1-29634
1072246-1078177 Z73327.1 1-5932
FEATURES Location/Qualifiers
source 1..1078177
/organism="Saccharomyces cerevisiae S288c"
/mol_type="genomic DNA"
/strain="S288c"
/db_xref="taxon:559292"
/chromosome="XII"
telomere complement(1..12085)
/note="TEL12L; Telomeric region on the left arm of
Chromosome XII, composed of an X element core sequence, X
element combinatorial repeats, and three distinct regions
of telomeric repeats separated by two short Y' elements"
/db_xref="SGD:S000028910"
repeat_region complement(1..75)
/note="TEL12L-TR1; Terminal stretch of telomeric repeats
on the left arm of Chromosome XII"
/rpt_family="Telomeric Repeat"
/db_xref="SGD:S000028911"
repeat_region complement(76..5661)
/note="TEL12L-YP1; More end-proximal of two short
telomeric Y' elements on the left arm of Chromosome XII;
contains an ARS consensus sequence, a region of 36-bp
repeats, and two ORFs YLL067C and YLL067W-A"
/rpt_family="Y' element"
/db_xref="SGD:S000028916"
gene complement(585..4301)
/locus_tag="YLL067C"
/db_xref="GeneID:850659"
mRNA complement(join(585..3915,4015..4301))
/locus_tag="YLL067C"
/product="Y' element ATP-dependent helicase"
/transcript_id="NM_001181887.1"
/db_xref="GI:296146478"
/db_xref="GeneID:850659"
CDS complement(join(585..3915,4015..4301))
/locus_tag="YLL067C"
/EC_number="3.6.1.-"
/note="Putative Y' element ATP-dependent helicase"
/codon_start=1
/product="Y' element ATP-dependent helicase"
/protein_id="NP_013033.1"
/db_xref="GI:6322961"
/db_xref="SGD:S000003990"
/db_xref="GeneID:850659"
/translation="MRTFTDFVSGAPIVRSLQKSTIRRYGYNLAPHMFLLLHVDELSI
FSAYQASLPGEKKVDTERLKRDLCPRKPIEIKYFSQICNDMMNKKDRLGDVLATAQRI
RRRYNKNGSSEPRLKTLDGLTSERWIQWLGLESDYHCSFSSTRNAEDVVAGEAASSDH
DQKISRVTRKRPREPKSTNDILVAGQKLFGSSFEFRDLHQLRLCHEIYMADTPSVAVQ
APPGYGKTELFHLPLIALASKGDVKYVSFLFVPYTVLLANCMIRLGRCGCLNVAPVRN
FIEEGCDGVTDLYVGIYDDLASTNFTDRIAAWENIVECTFRTNNVKLGYLIVDEFHNF
ETEVYRQSQFGGITNLDFDAFEKAIFLSGTAPEAVADAALQRIGLTGLAKKSMDINEL
KRSEDLSRGLSSYPTRMFNLIKEKSEVPLGHVHKIWKKVESQPEEALKLLLALFEIEP
ESKAIVVASTTNEVEELACSWRKYFRVVWIHGKLGAAEKVSRTKEFVTDGSMRVLIGT
KLVTEGIDIKQLMMVIMLDNRLNIIELIQGVGRLRDGGLCYLLSRKNSWAARNRKGEL
PPIKEGCITEQVREFYGLESKKGKKGQHVGCCGSRTDLSADTVELIERMDRLAEKQAT
ASMSIVALPSSFQESNSSDRCRKYCSSDEDSNTCIHGSANASTNATTNSSTNATTTAS
TNVRTSATTTASINVRTSATTTESTNSSTNATTTASTNVRTSATTTASINVRTSATTT
ESTNSNTSATTTESTDSNTSATTTESTDSSTNATTTASINVRTSATTTESTNSNTNAT
TTESTNSSTNATTTEGTNSNTSATTTASTNSSTNATTTESTNASAKEDANKDGNAEDN
RFHPVTDINKESYKRKGSQMVLLERKKLKAQFPNTSENMNVLQFLGFRSDEIKHLFLY
GIDVYFCPEGVFTQYGLCKGCQKMFELCVCWAGQKVSYRRMAWEALAVERMLRNDEEY
KEYLEDIEPYHGDPVGYLKFFSVKRGEIYSQIQRNYAWYLAITRRRETISVLDSTRGK
QGSQVFRMSGRQIKELYYKVWSNLRESKTEVLQYFLNWDEKKCREEWEAKDDTVFVEA
LEKVGVFQRLRSMTSAGLQGPQYVKLQFSRHHRQLRSRYELSLGMHLRDQLALGVTPS
KVPHWTAFLSMLIGLFYNKTFRQKLEYLLEQISEVWLLPHWVDLANVEVLAADNTRVP
C"
gene 5605..5775
/locus_tag="YLL066W-B"
/db_xref="GeneID:1466404"
mRNA 5605..5775
/locus_tag="YLL066W-B"
/product="hypothetical protein"
/transcript_id="NM_001184605.1"
/db_xref="GI:296146479"
/db_xref="GeneID:1466404"
CDS 5605..5775
/locus_tag="YLL066W-B"
/note="hypothetical protein; overexpression causes a cell
cycle delay or arrest"
/codon_start=1
/product="hypothetical protein"
/protein_id="NP_878115.1"
/db_xref="GI:33438827"
/db_xref="SGD:S000028672"
/db_xref="GeneID:1466404"
/translation="MSLRPCLTPSSMQYSDIYIHHTHTPHPHHTHTHTHHTPTHSLTS
TFTLAVTPYPAF"
repeat_region complement(5662..5723)
/note="TEL12L-TR2; Middle stretch of telomeric repeats on
the left arm of Chromosome XII"
/rpt_family="Telomeric Repeat"
/db_xref="SGD:S000028912"
repeat_region complement(5724..11196)
/note="TEL12L-YP2; More centromere-proximal of two short
Y' elements in the left telomere of Chromosome XII;
contains an ARS consensus sequence, a region of 36-bp
repeats, and two ORFs YLL066C and YLL066W-A"
/rpt_family="Y' element"
/db_xref="SGD:S000028917"
gene complement(6120..9836)
/locus_tag="YLL066C"
/db_xref="GeneID:850660"
mRNA complement(join(6120..9450,9550..9836))
/locus_tag="YLL066C"
/product="Y' element ATP-dependent helicase"
/transcript_id="NM_001181886.1"
/db_xref="GI:296146480"
/db_xref="GeneID:850660"
CDS complement(join(6120..9450,9550..9836))
/locus_tag="YLL066C"
/EC_number="3.6.1.-"
/note="Putative Y' element ATP-dependent helicase; YLL066C
is not an essential gene"
/codon_start=1
/product="Y' element ATP-dependent helicase"
/protein_id="NP_013034.1"
/db_xref="GI:6322962"
/db_xref="SGD:S000003989"
/db_xref="GeneID:850660"
/translation="MRTFTDFVSGAPIVRSLQKSTIRRYGYNLAPHMFLLLHVDELSI
FSAYQASLPGEKKVDTERLKRDLCPRKPIEIKYFSQICNDMMNKKDRLGDVLATAQRI
RRRYNKNGSSEPRLKTLDGLTSERWIQWLGLESDYHCSFSSTRNAEDVVAGEAASSDH
DQKISRVTRKRPREPKSTNDILVAGQKLFGSSFEFRDLHQLRLCHEIYMADTPSVAVQ
APPGYGKTELFHLPLIALASKGDVKYVSFLFVPYTVLLANCMIRLGRCGCLNVAPVRN
FIEEGCDGVTDLYVGIYDDLASTNFTDRIAAWENIVECTFRTNNVKLGYLIVDEFHNF
ETEVYRQSQFGGITNLDFDAFEKAIFLSGTAPEAVADAALQRIGLTGLAKKSMDINEL
KRSEDLSRGLSSYPTRMFNLIKEKSEVPLGHVHKIWKKVESQPEEALKLLLALFEIEP
ESKAIVVASTTNEVEELACSWRKYFRVVWIHGKLGAAEKVSRTKEFVTDGSMRVLIGT
KLVTEGIDIKQLMMVIMLDNRLNIIELIQGVGRLRDGGLCYLLSRKNSWAARNRKGEL
PPIKEGCITEQVREFYGLESKKGKKGQHVGCCGSRTDLSADTVELIERMDRLAEKQAT
ASMSIVALPSSFQESNSSDRCRKYCSSDEDSNTCIHGSANASTNATTNSSTNATTTAS
TNVRTSATTTASINVRTSATTTESTNSSTNATTTASTNVRTSATTTASINVRTSATTT
ESTNSNTSATTTESTDSNTSATTTESTDSNTSATTTASTNSSTNATTTASTNSSTNAT
TTESTNASAKEDANKDGNAEDNRFHPVTDINKESYKRKGSQMVLLERKKLKAQFPNTS
ENMNVLQFLGFRSDEIKHLFLYGIDIYFCPEGVFTQYGLCKGCQKMFGLCVCWAGQKV
SYRRMAWEALAVERMLRNDEEYKEYLEDIEPYHGDPVGYLKFFSVKRGEIYSQIQRNY
AWYLAITRRRETISVLDSTRGKQGSQVFRMSGRQIKELYYKVWSNLRESKTEVLQYFL
NWDEKKCREEWEAKDDTVFVEALEKVGVFQRLRSMTSAGLQGPQYVKLQFSRHHRQLR
SRYELSLGMHLRDQLALGVTPSKVPHWTAFLSMLIGLFYNKTFRQKLEYLLEQISEVW
LLPHWVDLANVEVLAADNTRVPLYMLMVAVHKELDSDDVPDGRFDIILLCRDSSREVG
E"
repeat_region complement(11197..11358)
/note="TEL12L-TR3; Internal stretch of telomeric repeats
on the left arm of Chromosome XII"
/rpt_family="Telomeric Repeat"
/db_xref="SGD:S000028913"
repeat_region complement(11359..11625)
/note="TEL12L-XR; Telomeric X element combinatorial Repeat
region on the left arm of Chromosome XII; contains repeats
of the D, C, B and A types, as well as Tbf1p binding
sites; formerly called SubTelomeric Repeats"
/rpt_family="X element Combinatorial Repeats"
/db_xref="SGD:S000028915"
repeat_region complement(11626..12085)
/note="TEL12L-XC; Telomeric X element Core sequence on the
left arm of Chromosome XII; contains an ARS consensus
sequence, an Abf1p binding site consensus sequence, and
ORF YLL065W"
/rpt_family="X element Core sequence"
/db_xref="SGD:S000028914"
gene complement(13083..13445)
/gene="PAU18"
/locus_tag="YLL064C"
/db_xref="GeneID:850662"
mRNA complement(13083..13445)
/gene="PAU18"
/locus_tag="YLL064C"
/product="Pau18p"
/transcript_id="NM_001181884.1"
/db_xref="GI:296146481"
/db_xref="GeneID:850662"
CDS complement(13083..13445)
/gene="PAU18"
/locus_tag="YLL064C"
/note="hypothetical protein, member of the seripauperin
multigene family encoded mainly in subtelomeric regions;
identical to Pau6p"
/codon_start=1
/product="Pau18p"
/protein_id="NP_013036.1"
/db_xref="GI:6322964"
/db_xref="SGD:S000003987"
/db_xref="GeneID:850662"
/translation="MVKLTSIAAGVAAIAATASATTTLAQSDERVNLVELGVYVSDIR
AHLAQYYMFQAAHPTETYPVEVAEAVFNYGDFTTMLTGIAPDQVTRMITGVPWYSTRL
KPAISKALSKDGIYTIAN"
gene complement(14648..16072)
/gene="AYT1"
/locus_tag="YLL063C"
/db_xref="GeneID:850663"
mRNA complement(14648..16072)
/gene="AYT1"
/locus_tag="YLL063C"
/product="Ayt1p"
/transcript_id="NM_001181883.1"
/db_xref="GI:296146482"
/db_xref="GeneID:850663"
CDS complement(14648..16072)
/gene="AYT1"
/locus_tag="YLL063C"
/EC_number="2.3.1.-"
/note="Acetyltransferase; catalyzes trichothecene
3-O-acetylation, suggesting a possible role in
trichothecene biosynthesis"
/codon_start=1
/product="Ayt1p"
/protein_id="NP_013037.1"
/db_xref="GI:6322965"
/db_xref="SGD:S000003986"
/db_xref="GeneID:850663"
/translation="MFRVKIISQKRTKSVQMLENDQLDILGQQPSLYKLYTQICSIYR
VPDPSAHDHIVNTLTRGLETLAKNFQWLAGNVVNEGADEGNTGTYRIVPSDKIPLIVQ
DLREDLSAPTMDSLEKADFPIYMLDEKTFAPCMTINPPGNTIGMAAKSGPVFAVQANF
ISGGLVLTIVGQHNIMDITGQESIINLLNKSCHQKPFSDEELLIGNIDKSKSIPLFDE
TWEPDTTLVHEIVETSRNTSGEEKEQSCSSNSTWAYVEFSAISLQNLRILAMQTCTSG
TKFVSTDDIVTAFIWKSVSRARLSRLKPETKSNLGRAVDVRKRLGLPETYPGLLVNMT
FNTGSLKSLDHKSLGVLASQIRRKLDPKVFDLAYNTCALATLLSRCPDKTKVSIPQPI
DTLSGIMVSSWAKVSLYDVDFNLGLGKPKSVRRPRFISLESLIYFMPRSSRGEMVVAL
CLRDKDWECLNADKEWTNYATHIG"
gene complement(16639..17613)
/gene="MHT1"
/locus_tag="YLL062C"
/db_xref="GeneID:850664"
mRNA complement(16639..17613)
/gene="MHT1"
/locus_tag="YLL062C"
/product="Mht1p"
/transcript_id="NM_001181882.1"
/db_xref="GI:296146483"
/db_xref="GeneID:850664"
CDS complement(16639..17613)
/gene="MHT1"
/locus_tag="YLL062C"
/EC_number="2.1.1.10"
/note="S-methylmethionine-homocysteine methyltransferase,
functions along with Sam4p in the conversion of
S-adenosylmethionine (AdoMet) to methionine to control the
methionine/AdoMet ratio"
/codon_start=1
/product="Mht1p"
/protein_id="NP_013038.1"
/db_xref="GI:6322966"
/db_xref="SGD:S000003985"
/db_xref="GeneID:850664"
/translation="MKRIPIKELIVEHPGKVLILDGGQGTELENRGININSPVWSAAP
FTSESFWEPSSQERKVVEEMYRDFMIAGANILMTITYQANFQSISENTSIKTLAAYKR
FLDKIVSFTREFIGEERYLIGSIGPWAAHVSCEYTGDYGPHPENIDYYGFFKPQLENF
NQNRDIDLIGFETIPNFHELKAILSWDEDIISKPFYIGLSVDDNSLLRDGTTLEEISV
HIKGLGNKINKNLLLMGVNCVSFNQSALILKMLHEHLPGMPLLVYPNSGEIYNPKEKT
WHRPTNKLDDWETTVKKFVDNGARIIGGCCRTSPKDIAEIASAVDKYS"
gene 17956..19707
/gene="MMP1"
/locus_tag="YLL061W"
/db_xref="GeneID:850665"
mRNA 17956..19707
/gene="MMP1"
/locus_tag="YLL061W"
/product="Mmp1p"
/transcript_id="NM_001181881.1"
/db_xref="GI:296146484"
/db_xref="GeneID:850665"
CDS 17956..19707
/gene="MMP1"
/locus_tag="YLL061W"
/note="High-affinity S-methylmethionine permease, required
for utilization of S-methylmethionine as a sulfur source;
has similarity to S-adenosylmethionine permease Sam3p"
/codon_start=1
/product="Mmp1p"
/protein_id="NP_013039.1"
/db_xref="GI:6322967"
/db_xref="SGD:S000003984"
/db_xref="GeneID:850665"
/translation="MDEFESTKLSKVQFSTSVLSTPSNEGNNLIHRFKNSFKRNDSPA
IQEGLLYSELSEEEKIQWDLANQPYKKVLDQRHLTMIAIGGTLGTGLFIGLGESLASG
PASLLIGFLLVGASMLCVVQCGAELSCQYPVSGSYALHASRFIDPSVGFSIGINYLLM
WLISYPSELVGCSLTISYWAPSVNPAAWVAIAFVLSMLLNLFGARGFAESEFYMSIFK
IVALFIFIIIGIVLIAGGGPDSTGYIGTKYWHDPGSFAVPVFKNLCNTFVSAAYSFSG
TEMVVLTSTEARSVSSVSRAAKGTFWRIIIFYIVTVIIIGCLVPYNDPRLISGSSSED
ITASPFVIALSNTGAMGTRVSHFMNAVILIAVFSVCNSCVYASSRLIQGLATAGQLPK
ICAYMDRNGRPLVGMAICGAFGLLGFLVVSKNQGTVFTWLFALCSISFFTTWFCICFC
QVRFRMAMKAQGRSKDDIIYRSTLGIYGGIFGCILNVLLVIGEIYVSAAPVGSPSSAA
NFFEYCMSIPIMIAVYIGHRIYRRDWRHWYIKRMDIDLDSGHSLEDFEATKLERDEDK
KYVSSKPLYYRIYRFFC"
gene complement(21138..21839)
/gene="GTT2"
/locus_tag="YLL060C"
/db_xref="GeneID:850666"
mRNA complement(21138..21839)
/gene="GTT2"
/locus_tag="YLL060C"
/product="glutathione transferase GTT2"
/transcript_id="NM_001181880.1"
/db_xref="GI:296146485"
/db_xref="GeneID:850666"
CDS complement(21138..21839)
/gene="GTT2"
/locus_tag="YLL060C"
/EC_number="2.5.1.18"
/note="Glutathione S-transferase capable of
homodimerization; functional overlap with Gtt2p, Grx1p,
and Grx2p; protein abundance increases in response to DNA
replication stress"
/codon_start=1
/product="glutathione transferase GTT2"
/protein_id="NP_013040.1"
/db_xref="GI:6322968"
/db_xref="SGD:S000003983"
/db_xref="GeneID:850666"
/translation="MNGRGFLIYNGGEKMKQKMIIYDTPAGPYPARVRIALAEKNMLS
SVQFVRINLWKGEHKKPEFLAKNYSGTVPVLELDDGTLIAECTAITEYIDALDGTPTL
TGKTPLEKGVIHMMNKRAELELLDPVSVYFHHATPGLGPEVELYQNKEWGLRQRDKAL
HGMHYFDTVLRERPYVAGDSFSMADITVIAGLIFAAIVKLQVPEECEALRAWYKRMQQ
RPSVKKLLEIRSKSS"
gene 23569..25296
/locus_tag="YLL058W"
/db_xref="GeneID:850668"
mRNA 23569..25296
/locus_tag="YLL058W"
/product="cystathionine gamma-synthase"
/transcript_id="NM_001181878.1"
/db_xref="GI:296146486"
/db_xref="GeneID:850668"
CDS 23569..25296
/locus_tag="YLL058W"
/EC_number="2.5.1.48"
/note="hypothetical protein with similarity to Str2p,
which is a cystathionine gamma-synthase important in
sulfur metabolism; YLL058W is not an essential gene"
/codon_start=1
/product="cystathionine gamma-synthase"
/protein_id="NP_013042.1"
/db_xref="GI:6322970"
/db_xref="SGD:S000003981"
/db_xref="GeneID:850668"
/translation="MTEIEFGQPLPSNLDYAVSFGIPTWDSAIGYAEKVPEVIGKMAT
GYPRYFPQPPVQRLCAYFVKKFGRGSENCRPFPSVNLGLKCFEYVKSVSGPESKAHLE
VETVTIKNRGAKTSKEPAELVLTIAAVLASEEEFETVKEYWKLRGECVSSRLALSVNQ
LLDCANHGSEQVLRELEAGVFAAKKGEEKAKNLIKGRIVENRFRPFGLEKKTPNWEGL
NLNPNEDVYLVSSGMSAISTARNLLTFWEEKKNSGDSLNKTTSDQKKKPLLCDTVGIF
GFPFKDTQVIMTKFGKCKFFGFGNSRDVVELQKFLETSKQRILAVFVETPSNPLLNMP
DLKKLRSLADQYGFFIVIDDTIGGLNVDILPYADIVSTSLTKLFNGASNVMGGSVVLN
PKSSLYPYAREYFRSANFEDLLWCEDAIVLERNSRDFEDRTLRANANTGILLNDLLLP
EEGKICKKIYYPTVTSKETFENYESVRNERGGYGCLFSVAFFNEGDAKAFYDSLKVFK
GPSNGTNFTLACPYVHLAHHSELEEVSKFGADPNIIRVSVGLEDIQWLLKVFSSALDV
VKSRGSKHS"
gene complement(25756..26994)
/gene="JLP1"
/locus_tag="YLL057C"
/db_xref="GeneID:850669"
mRNA complement(25756..26994)
/gene="JLP1"
/locus_tag="YLL057C"
/product="Jlp1p"
/transcript_id="NM_001181877.1"
/db_xref="GI:296146487"
/db_xref="GeneID:850669"
CDS complement(25756..26994)
/gene="JLP1"
/locus_tag="YLL057C"
/EC_number="1.14.11.-"
/note="Fe(II)-dependent sulfonate/alpha-ketoglutarate
dioxygenase, involved in sulfonate catabolism for use as a
sulfur source; contains sequence that resembles a J domain
(typified by the E. coli DnaJ protein); induced by sulphur
starvation"
/codon_start=1
/product="Jlp1p"
/protein_id="NP_013043.1"
/db_xref="GI:6322971"
/db_xref="SGD:S000003980"
/db_xref="GeneID:850669"
/translation="MSPAAAQTAIPLPSTDLPVKIITNGLKNLNYTSKQGYGNFDTHF
YDGQDEVSPSGLLKIRKSYREKSKYPDYLPTWDPTEKYGPLEFHEYHDPALRADGNFS
NLFAKENVGQLKVKKITPKLGLEINGIQLTDLSDAAKDELALLVAQKGVVVFRNQNFA
DEGPDYVTEYGRHFGKLHIHQTSGHPQNNPELHITFRRPDAEEFARVFDDSTSSGGWH
TDVSYELQPPSYTFFSVVEGPDGGGDTLFADTIEAFDRLSKPLQDFLSTLHVIHSSKE
QAENSQRQGGIKRRAPVTHIHPLVRVHPVLKKKCLYVNRAFSRKIVELKRQESESLLN
FLYNLVESSHDLQLRAKWEPHSVVIWDNRRVQHSAVIDWEEPIHRHAFRITPQAERPV
EDLKFLNDENYYPSSLTLDI"
gene complement(27409..28305)
/locus_tag="YLL056C"
/db_xref="GeneID:850670"
mRNA complement(27409..28305)
/locus_tag="YLL056C"
/product="hypothetical protein"
/transcript_id="NM_001181876.1"
/db_xref="GI:296146488"
/db_xref="GeneID:850670"
CDS complement(27409..28305)
/locus_tag="YLL056C"
/note="hypothetical protein, transcription is activated by
paralogous transcription factors Yrm1p and Yrr1p and genes
involved in pleiotropic drug resistance (PDR); expression
is induced in cells treated with the mycotoxin patulin"
/codon_start=1
/product="hypothetical protein"
/protein_id="NP_013044.1"
/db_xref="GI:6322972"
/db_xref="SGD:S000003979"
/db_xref="GeneID:850670"
/translation="MKVFITGASGFIGSAVLSELISSGHEVVGLARSDEAAAKIKSID
PAAKILRGDLKDLEILKKGATESDGVIHLGFVHDFKNFEQCCEIDRQATVAMLESLKG
SNKPFLYTNGTLSLRPNKVANEQDGIDEDSKILRAVTEQVALSYKDKGVSARIVRLPF
SVHGKGDKAFVPILMNIAKAAGKSGYVGQGTNAWAAVHRLDTAPLFRLVLEKGKTGQV
YHCVGEQGIPFKDIARVIGEILNVPVASIPVDDAESHFGFLTCFVTRDGPVSSEGTRK
ELGWQPQQIGLLEDIRANYSLN"
gene 30109..31704
/gene="YCT1"
/locus_tag="YLL055W"
/db_xref="GeneID:850671"
mRNA 30109..31704
/gene="YCT1"
/locus_tag="YLL055W"
/product="Yct1p"
/transcript_id="NM_001181875.1"
/db_xref="GI:296146489"
/db_xref="GeneID:850671"
CDS 30109..31704
/gene="YCT1"
/locus_tag="YLL055W"
/note="High-affinity cysteine-specific transporter with
similarity to the Dal5p family of transporters; green
fluorescent protein (GFP)-fusion protein localizes to the
endoplasmic reticulum; YCT1 is not an essential gene"
/codon_start=1
/product="Yct1p"
/protein_id="NP_013045.1"
/db_xref="GI:6322973"
/db_xref="SGD:S000003978"
/db_xref="GeneID:850671"
/translation="MSKVDVKIGADSISSSDEILVPSRLADVTLAFMEENDAAVPEIT
PEQEKKLKRKLFLTIFTFVSAINLLLYMDKATLSYDSILGFFEDTGLTQNTYNTVNTL
FYVGFAIGQFPGQYLAQKLPLGKFLGGLLATWTILIFLSCTAYNFSGVVALRFFLGLT
ESVVIPILITTMGMFFDASERAAAQPFFFAACMGSPIPTGFIAYGVLHITNPSISLWK
IFTIIIGGLTFIMTVVVILWFPNNPADVKFFSIQERVWIIRRVQASTGSSIEQKVFKK
SQFREAMKDYITWLFGLFFLLQQLANNLPYQQNLLFEGMGGVDALGSTLVSVAGAGFA
VVCAFIATLMLAKWKNISALTAIFWTLPALVGSIAAAALPWDNKIGILANICMAGQIF
GIPFIIALSWASSSASGYTKKLTRSSVSLFAMGIANIISPQIWREKDSPRFLPAWIVQ
IVLSFSLAPAILLLIHFILKRRNNQRLKNYDENLQNYLDRIQLIESENPSSIEEGKVV
THENNLAVFDLTDLENETFIYPL"
rep_origin 30209..31384
/gene="YCT1"
/locus_tag="YLL055W"
/note="ARS1202;
Putative replication origin, identified in multiple array
studies, not yet confirmed by plasmid-based assay"
/db_xref="SGD:S000130180"
gene complement(32673..35204)
/locus_tag="YLL054C"
/db_xref="GeneID:850672"
mRNA complement(32673..35204)
/locus_tag="YLL054C"
/product="hypothetical protein"
/transcript_id="NM_001181874.2"
/db_xref="GI:330443668"
/db_xref="GeneID:850672"
CDS complement(32673..35204)
/locus_tag="YLL054C"
/note="hypothetical protein with similarity to Pip2p, an
oleate-specific transcriptional activator of peroxisome
proliferation; YLL054C is not an essential gene"
/codon_start=1
/product="hypothetical protein"
/protein_id="NP_013046.2"
/db_xref="GI:330443669"
/db_xref="SGD:S000003977"
/db_xref="GeneID:850672"
/translation="MSIASQKKVKPSFVCLRCKQRKIKCDKLWPTCSKCKASSSICSY
EVEPGRINKSPTIENAPHRDIRNITPASMSASGSFTSILNPSTKDWEMKNFAMNLSNA
HDKLVVMNNTTIVDSPFAFHSILQHDLYAKALTTCIHERILIDVERHRENVSANNKKR
ELNLTIGDIGPLFFIDKAALKFIENTSKTSKLYPPIDFLYNTYDYEQAHPEENNDKIS
INILLEELSKYFLNKNEVDGLIVDFYKTIYPVYPLLEISLFEDNIRELLQLNEFNGYN
IVFAGKDSRRKLETITLLTIILAFSYRRLSLSTSHSFKESFGVKSNNLTLLAHKLLAL
MNVFQYVNEHTLCCLLYFFILRYLNPDQADMYPTHSDILNLKFLENVAIKLGLNEEPF
QYTRYVSESDDYPRLFNLRRKLWLGVQFLKFGILIPEGDSDILSLEYLRSFMKTDESL
PELFERNYASTNNLDLSLMATAENIYHLHLSLQVLLTSCFPINGPSYLKEVLDNIDKT
KDFLNQKFPLILSSLGEPRMKSLHINVPSSLANEESFDFSTFEENETFIANVISYTCT
MNIYDSLSLHFENQCFKNALEYKTYYHRFTFTAIQDYLTLLKLISEYFNGSLLHLREP
FGFATQKVVRFSIHRLLIFQATLLVRLFYKKDTCDRSSAAMGMLNDRNGRLSRVIEKM
IKLMSYHMKLLVEIVISKLEKSYLGSFISVSIFRYIIYLVDTDALSAFISDYWKSDAV
MDERYSRIHRIVGLKWGMGRDKSFSFTSKLNNPQFLGSLDLEILEELEKLISAQEFSR
NFTEDVDESLQSEIDLMNYDNEALNQLMAIDLDKLLGIFPNLSNF"
gene complement(35503..35961)
/locus_tag="YLL053C"
/db_xref="GeneID:850673"
mRNA complement(35503..35961)
/locus_tag="YLL053C"
/product="hypothetical protein"
/transcript_id="NM_001181873.1"
/db_xref="GI:296146491"
/db_xref="GeneID:850673"
CDS complement(35503..35961)
/locus_tag="YLL053C"
/note="Putative protein; in the Sigma 1278B strain
background YLL053C is contiguous with AQY2 which encodes
an aquaporin"
/codon_start=1
/product="hypothetical protein"
/protein_id="NP_013047.1"
/db_xref="GI:6322975"
/db_xref="SGD:S000003976"
/db_xref="GeneID:850673"
/translation="MWFPQIIAGMAAGGAASAMTPGKVLFTNALGLGCSRSRGLFLEM
FGTAVLCLTVLMTAVEKRETNFMAALPIGISLFMAHMALTGYTGTGVNPARSLGAAVA
ARYFPHYHWIYWISPLLGAFLAWSVWQLLQILDYTTYVNAEKAAGQKKED"
gene complement(35912..36361)
/gene="AQY2"
/locus_tag="YLL052C"
/db_xref="GeneID:850674"
mRNA complement(35912..36361)
/gene="AQY2"
/locus_tag="YLL052C"
/product="Aqy2p"
/transcript_id="NM_001181872.1"
/db_xref="GI:296146492"
/db_xref="GeneID:850674"
CDS complement(35912..36361)
/gene="AQY2"
/locus_tag="YLL052C"
/note="Water channel that mediates the transport of water
across cell membranes, only expressed in proliferating
cells, controlled by osmotic signals, may be involved in
freeze tolerance; disrupted by a stop codon in many S.
cerevisiae strains"
/codon_start=1
/product="Aqy2p"
/protein_id="NP_013048.1"
/db_xref="GI:6322976"
/db_xref="SGD:S000003975"
/db_xref="GeneID:850674"
/translation="MSNESNDLEKNISHLDPTGVDNAYIPPEQPETKHSRFNIDRDTL
RNHFIAAVGEFCGTFMFLWCAYVICNVANHDVALTTEPEGSHPGQLIMIALGFGFSVM
FSIWCFWWGFEPSRFSLFVFGQSHLTSQMCSDVVSSDHCWDGCWWCR"
gene complement(37333..39471)
/gene="FRE6"
/locus_tag="YLL051C"
/db_xref="GeneID:850675"
mRNA complement(37333..39471)
/gene="FRE6"
/locus_tag="YLL051C"
/product="Fre6p"
/transcript_id="NM_001181871.1"
/db_xref="GI:296146493"
/db_xref="GeneID:850675"
CDS complement(37333..39471)
/gene="FRE6"
/locus_tag="YLL051C"
/EC_number="1.16.1.7"
/note="Putative ferric reductase with similarity to Fre2p;
expression induced by low iron levels"
/codon_start=1
/product="Fre6p"
/protein_id="NP_013049.1"
/db_xref="GI:6322977"
/db_xref="SGD:S000003974"
/db_xref="GeneID:850675"
/translation="MHRTLLFLTWLISLTKAFNIKLPHTEKKDHLESNAVLACASYIN
TLKWSFDSSVVPGFYSTICSYSPAFDTWSLCIFNSLTDQIIPMDNTSFEESLGNVRKT
CSFVDKKFSNISLEQYYSSLNNASSHALEDYGSIESLSTSIRVDRETRSRWIRAFHAH
AYNLDISSVYGAYLTYYFVIVGIIAVFFHMSHYNGLNRALFASRFVNYIRGHFVLPTF
LVDKHANHFKFLNVEVFTGLMPNSLEAWIIFGYTLANIIFLSISYIIDPYNLIFNSHL
SQFTRLLADRSGILAFTQFPLIIIFTARNSFLEFLTGVKFNSFISFHKWIGRIMVLNA
TIHSLSYSLFAIINHAFKISNKQLYWKFGIASITVLCVLLVLSLGIVRKRHYEFFLYT
HIILALLFFYCCWQHVKIFNGWKEWIVVSLLIWGLEKLFRIWNILQFRFPKATLINLN
TSNNPHDEMFKVIIPKYNRRWHSKPGQYCFIYFLHPLVFWQCHPFTIIDEGEKCVLVI
KPKSGLTRFIYNHILQSLNGKLQLRVAIEGPYGPSNLHLDKFDHLLLLSGGTGLPGPL
DHAIKLSRNPDKPKSIDLIMAIKNPSFLNGYKSEILELKNSRSHVNVQVYLTQKTAVT
KAANARDQLIHFDDIMTELTSFAHIGNARPNFSNVIENAIKSTPPGDSLAVVCCGPPV
LVDDVRNTVSQKLLGYPERIIEYFEEYQCW"
gene complement(39804..40414)
/gene="COF1"
/locus_tag="YLL050C"
/db_xref="GeneID:850676"
mRNA complement(join(39804..40221,40401..40414))
/gene="COF1"
/locus_tag="YLL050C"
/product="Cof1p"
/transcript_id="NM_001181870.1"
/db_xref="GI:296146494"
/db_xref="GeneID:850676"
CDS complement(join(39804..40221,40401..40414))
/gene="COF1"
/locus_tag="YLL050C"
/note="Cofilin, promotes actin filament depolarization in
a pH-dependent manner; binds both actin monomers and
filaments and severs filaments; thought to be regulated by
phosphorylation at SER4; ubiquitous and essential in
eukaryotes"
/codon_start=1
/product="Cof1p"
/protein_id="NP_013050.1"
/db_xref="GI:6322978"
/db_xref="SGD:S000003973"
/db_xref="GeneID:850676"
/translation="MSRSGVAVADESLTAFNDLKLGKKYKFILFGLNDAKTEIVVKET
STDPSYDAFLEKLPENDCLYAIYDFEYEINGNEGKRSKIVFFTWSPDTAPVRSKMVYA
SSKDALRRALNGVSTDVQGTDFSEVSYDSVLERVSRGAGSH"
gene 40666..41205
/gene="LDB18"
/locus_tag="YLL049W"
/db_xref="GeneID:850677"
mRNA 40666..41205
/gene="LDB18"
/locus_tag="YLL049W"
/product="Ldb18p"
/transcript_id="NM_001181869.1"
/db_xref="GI:296146495"
/db_xref="GeneID:850677"
CDS 40666..41205
/gene="LDB18"
/locus_tag="YLL049W"
/note="Component of the dynactin complex, which is
required for dynein activity; null mutant exhibits defects
in nuclear migration and spindle orientation and has
reduced affinity for alcian blue dye; has homology to
mammalian dynactin subunit p24"
/codon_start=1
/product="Ldb18p"
/protein_id="NP_013051.1"
/db_xref="GI:6322979"
/db_xref="SGD:S000003972"
/db_xref="GeneID:850677"
/translation="MPGLKLVEALEYRCDRLERLIGAGYSANSDVSVQLDELYNQLHR
LYFQGLKYSQDLLQLFNTFMAEDIENVGAPDDICIFASCFDDIYTLYSAFDELNSQYM
EFCQISKSSLDQISFKDANIETKQLKKLPELVDNCNIMILRSIAILNRFIDWNIEVNG
FFQFQKKRLLNLQKVIYST"
gene complement(41280..46265)
/gene="YBT1"
/locus_tag="YLL048C"
/gene_synonym="BAT1"
/db_xref="GeneID:850678"
mRNA complement(41280..46265)
/gene="YBT1"
/locus_tag="YLL048C"
/gene_synonym="BAT1"
/product="bile acid-transporting ATPase YBT1"
/transcript_id="NM_001181868.1"
/db_xref="GI:296146496"
/db_xref="GeneID:850678"
CDS complement(41280..46265)
/gene="YBT1"
/locus_tag="YLL048C"
/gene_synonym="BAT1"
/note="Transporter of the ATP-binding cassette (ABC)
family; involved in bile acid transport; negative
regulator of vacuole fusion; regulates the release of
lumenal Ca2+ stores; similar to mammalian bile
transporters"
/codon_start=1
/product="bile acid-transporting ATPase YBT1"
/protein_id="NP_013052.1"
/db_xref="GI:6322980"
/db_xref="SGD:S000003971"
/db_xref="GeneID:850678"
/translation="MHHVLNSTRPDHRFWFYDDVTQYGRTKYLNYYTPLVLLIFTVLF
ITYNIWKHYYYYDVLHLKQKNPIDELLYSSTDEDEQSPLINNNTITTNYVDNNCTKDA
LKNRHFSLEKLKSVKVNGEPHGTPEIVRRGFIEKSRIILEFFLVLSQVIIHSFILLHY
VNKNPEFTQQGTITGLVEWCALFIIVSLRLANVNQNFKFINKYPGNLWSVSFINYLAL
FISMILPFRSIFIHHINSPISRKYYISQISINLALFLLLFFARIRNNFAIIYKTDSWI
TPSPEPVTSIAGFICWAWLDSFVWKAHKVSIKVKDIWGLMMQDYSFFVVKKFRYFVDH
KVKRKRIFSLNLFFFFSNYLVLQCFWAFLGSVLSFIPTVLLKRILEYVEDQSSAPSNL
AWFYVTVMFVGRILVAICQAQALFFGRRVCIRMKSIIISEIYTKALRRKISTNKTKPS
NEDPQEINDQKSINGDEESTSSANLGAIINLMAIDAFKVSEICGYLHSFLEAFVMTVV
ALALLYRLLGFAAIVGVLIIVAMLPLNYKLAKYIGDLQKKNLAVTDNRIQKLNEAFQA
IRIIKYFSWEENFEKDINTIRENELSLLLMRSIVWSISSFLWFVTPTIVTAASFAYYI
YVQGEVLTTPVAFTALSLFTLLRDPLDRLSDMLSFVVQSKVSLDRVQDFLNENDTKKY
DQLTIDPNGNRFAFENSTISWDKDNQDFKLKDLNIEFKTGKLNVVIGPTGSGKTSLLM
ALLGEMYLLNGKVVVPALEPRQELIVDANGTTNSIAYCSQAAWLLNDTVKNNILFNSP
FNEARYKAVVEACGLKRDFEILKAGDLTEIGEKGITLSGGQKQRVSLARALYSNARHV
LLDDCLSAVDSHTASWIYDNCITGPLMEDRTCILVSHNIALTLRNAELVVLLEDGRVK
DQGDPIDMLQKGLFGEDELVKSSILSRANSSANLAAKSSTSLSNLPAVKEQQVSVNNN
SSHFEAKKLQKSLRTEAERTEDGKLIKEETKEEGVVGLDVYKWYLKIFGGWKIVSFLA
SLFLIAQLLYIGQSWWVRAWASHNVIAKIIPRAQRAIAFISKKASHLIDWRGSSQISM
ASAENQPSSGHSTMYYLVLYLIIGFAQALLGAGKTILNFVAGINASRKIFNMILNKVL
HSKIRFFDATPTGRIMNRFSKDIEAIDQELTPYIQGAFYSLIECLSTVILITFITPQF
LSVAIVVSILYYFVGYFYMAGSRELKRFESISRSPIYQHFSETLVGVTTIRAFGDEGR
FMQENLHKIDENNKPFFYLWVANRWLAFRIDMIGSLVIFGAGLFILFNINNLDSGMAG
ISLTYAISFTEGALWLVRLYSEVEMNMNSVERVKEYMEIEQEPYNEHKEIPPPQWPQD
GKIEVNDLSLRYAPNLPRVIKNVSFSVDAQSKIGIVGRTGAGKSTIITALFRFLEPET
GHIKIDNIDISGVDLQRLRRSITIIPQDPTLFSGTIKTNLDPYDEFSDRQIFEALKRV
NLISEEQLQQGATRETSNEASSTNSENVNKFLDLSSEISEGGSNLSQGQRQLMCLARS
LLRSPKIILLDEATASIDYSSDAKIQETIRKEFQGSTILTIAHRLRSVIDYDKILVMD
AGEVKEYDHPYSLLLNKQSAFYSMCEHSGELDILIELAKKAFVEKLNSKKD"
gene complement(46714..47463)
/gene="RNP1"
/locus_tag="YLL046C"
/db_xref="GeneID:850680"
mRNA complement(46714..47463)
/gene="RNP1"
/locus_tag="YLL046C"
/product="Rnp1p"
/transcript_id="NM_001181866.1"
/db_xref="GI:296146497"
/db_xref="GeneID:850680"
CDS complement(46714..47463)
/gene="RNP1"
/locus_tag="YLL046C"
/note="Ribonucleoprotein that contains two RNA recognition
motifs (RRM)"
/codon_start=1
/product="Rnp1p"
/protein_id="NP_013054.1"
/db_xref="GI:6322982"
/db_xref="SGD:S000003969"
/db_xref="GeneID:850680"
/translation="MLIEEIEFYNVNGKKTTTVVPENTKIKKRVLNDRRTLYVGNLPK
NCRKQDLRDLFEPNYGKITINMLKKKPLKKPLKRFAFIEFQEGVNLKKVKEKMNGKIF
MNEKIVIENILTKEEKSFEKNQKSNKKTAPDLKPLSTNTLYVKNIPMKSTNEDLAKIF
GVDPKNINFVRRELVDLRTNKVFFSDEFHTGEAFIKFDNLGTGDSIQKKCREFKGRKA
SNGRVLLVKIASAKKNEQKQEGGDNTKIKQN"
gene complement(47859..48629)
/gene="RPL8B"
/locus_tag="YLL045C"
/gene_synonym="KRB1; SCL41"
/db_xref="GeneID:850682"
mRNA complement(47859..48629)
/gene="RPL8B"
/locus_tag="YLL045C"
/gene_synonym="KRB1; SCL41"
/product="ribosomal 60S subunit protein L8B"
/transcript_id="NM_001181865.1"
/db_xref="GI:296146498"
/db_xref="GeneID:850682"
CDS complement(47859..48629)
/gene="RPL8B"
/locus_tag="YLL045C"
/gene_synonym="KRB1; SCL41"
/note="Ribosomal 60S subunit protein L8B; mutation results
in decreased amounts of free 60S subunits; homologous to
mammalian ribosomal protein L7A, no bacterial homolog;
RPL8B has a paralog, RPL8A, that arose from the whole
genome duplication"
/codon_start=1
/product="ribosomal 60S subunit protein L8B"
/protein_id="NP_013055.1"
/db_xref="GI:6322984"
/db_xref="SGD:S000003968"
/db_xref="GeneID:850682"
/translation="MAPGKKVAPAPFGAKSTKSNKAKNPLTHSTPKNFGIGQAVQPKR
NLSRYVKWPEYVRLQRQKKILSIRLKVPPTIAQFQYTLDRNTAAETFKLFNKYRPETA
AEKKERLTKEAAAIAEGKSKQDASPKPYAVKYGLNHVVSLIENKKAKLVLIANDVDPI
ELVVFLPALCKKMGVPYAIIKGKARLGTLVNQKTSAVAALTEVRAEDEAALAKLVSTI
DANFADKYDEVKKHWGGGILGNKAQAKMDKRAKTSDSA"
gene 49938..51947
/gene="FPS1"
/locus_tag="YLL043W"
/db_xref="GeneID:850683"
mRNA 49938..51947
/gene="FPS1"
/locus_tag="YLL043W"
/product="Fps1p"
/transcript_id="NM_001181863.1"
/db_xref="GI:296146499"
/db_xref="GeneID:850683"
CDS 49938..51947
/gene="FPS1"
/locus_tag="YLL043W"
/note="Plasma membrane channel, member of major intrinsic
protein (MIP) family; involved in efflux of glycerol and
in uptake of acetic acid and the trivalent metalloids
arsenite and antimonite; phosphorylated by Hog1p MAPK
under acetate stress"
/codon_start=1
/product="Fps1p"
/protein_id="NP_013057.1"
/db_xref="GI:6322985"
/db_xref="SGD:S000003966"
/db_xref="GeneID:850683"
/translation="MSNPQKALNDFLSSESVHTHDSSRKQSNKQSSDEGRSSSQPSHH
HSGGTNNNNNNNNNNNNSNNNNNGNDGGNDDDYDYEMQDYRPSPQSARPTPTYVPQYS
VESGTAFPIQEVIPSAYINTQDINHKDNGPPSASSNRAFRPRGQTTVSANVLNIEDFY
KNADDAHTIPESHLSRRRSRSRATSNAGHSANTGATNGRTTGAQTNMESNESPRNVPI
MVKPKTLYQNPQTPTVLPSTYHPINKWSSVKNTYLKEFLAEFMGTMVMIIFGSAVVCQ
VNVAGKIQQDNFNVALDNLNVTGSSAETIDAMKSLTSLVSSVAGGTFDDVALGWAAAV
VMGYFCAGGSAISGAHLNPSITLANLVYRGFPLKKVPYYFAGQLIGAFTGALILFIWY
KRVLQEAYSDWWMNESVAGMFCVFPKPYLSSGRQFFSEFLCGAMLQAGTFALTDPYTC
LSSDVFPLMMFILIFIINASMAYQTGTAMNLARDLGPRLALYAVGFDHKMLWVHHHHF
FWVPMVGPFIGALMGGLVYDVCIYQGHESPVNWSLPVYKEMIMRAWFRRPGWKKRNRA
RRTSDLSDFSYNNDDDEEFGERMALQKTKTKSSISDNENEAGEKKVQFKSVQRGKRTF
GGIPTILEEEDSIETASLGATTTDSIGLSDTSSEDSHYGNAKKVT"
gene complement(52087..52590)
/gene="ATG10"
/locus_tag="YLL042C"
/gene_synonym="APG10"
/db_xref="GeneID:850684"
mRNA complement(52087..52590)
/gene="ATG10"
/locus_tag="YLL042C"
/gene_synonym="APG10"
/product="Atg10p"
/transcript_id="NM_001181862.1"
/db_xref="GI:296146500"
/db_xref="GeneID:850684"
CDS complement(52087..52590)
/gene="ATG10"
/locus_tag="YLL042C"
/gene_synonym="APG10"
/note="Conserved E2-like conjugating enzyme that mediates
formation of the Atg12p-Atg5p conjugate, which is a
critical step in autophagy"
/codon_start=1
/product="Atg10p"
/protein_id="NP_013058.1"
/db_xref="GI:6322986"
/db_xref="SGD:S000003965"
/db_xref="GeneID:850684"
/translation="MIPYQEWHSQLQSLYDSQIFHNWALCQDVHLNDEKDGLLLRLIP
TRQLQKNTERIENKLLNHIELYLTYSKVYNEPLLLLRIWEEKSIDGIPMTKLMLPTDI
ESLLDVQGKFQLGLDTIINLEGSVWYSFHPCDTSCIVGDQAEFMSTYLRRWVSIFIFS
WLGYEDS"
gene complement(53131..53931)
/gene="SDH2"
/locus_tag="YLL041C"
/gene_synonym="ACN17"
/db_xref="GeneID:850685"
mRNA complement(53131..53931)
/gene="SDH2"
/locus_tag="YLL041C"
/gene_synonym="ACN17"
/product="succinate dehydrogenase iron-sulfur protein
subunit SDH2"
/transcript_id="NM_001181861.1"
/db_xref="GI:296146501"
/db_xref="GeneID:850685"
CDS complement(53131..53931)
/gene="SDH2"
/locus_tag="YLL041C"
/gene_synonym="ACN17"
/EC_number="1.3.5.1"
/note="Iron-sulfur protein subunit of succinate
dehydrogenase (Sdh1p, Sdh2p, Sdh3p, Sdh4p), which couples
the oxidation of succinate to the transfer of electrons to
ubiquinone as part of the TCA cycle and the mitochondrial
respiratory chain"
/codon_start=1
/product="succinate dehydrogenase iron-sulfur protein
subunit SDH2"
/protein_id="NP_013059.1"
/db_xref="GI:6322987"
/db_xref="SGD:S000003964"
/db_xref="GeneID:850685"
/translation="MLNVLLRRKAFCLVTKKGMATATTAAATHTPRLKTFKVYRWNPD
EPSAKPHLQSYQVDLNDCGPMVLDALLKIKDEQDSTLTFRRSCREGICGSCAMNIGGR
NTLACICKIDQNESKQLKIYPLPHMFIVKDLVPDLTNFYQQYKSIQPYLQRSSFPKDG
TEVLQSIEDRKKLDGLYECILCACCSTSCPSYWWNQEQYLGPAVLMQAYRWLIDSRDQ
ATKTRKAMLNNSMSLYRCHTIMNCTRTCPKGLNPGLAIAEIKKSLAFA"
gene complement(54211..63645)
/gene="VPS13"
/locus_tag="YLL040C"
/gene_synonym="SOI1; VPT2"
/db_xref="GeneID:850619"
mRNA complement(54211..63645)
/gene="VPS13"
/locus_tag="YLL040C"
/gene_synonym="SOI1; VPT2"
/product="Vps13p"
/transcript_id="NM_001181860.1"
/db_xref="GI:296146502"
/db_xref="GeneID:850619"
CDS complement(54211..63645)
/gene="VPS13"
/locus_tag="YLL040C"
/gene_synonym="SOI1; VPT2"
/note="hypothetical protein; heterooligomeric or
homooligomeric complex; peripherally associated with
membranes; involved in sporulation, vacuolar protein
sorting, prospore membrane formation and protein-Golgi
retention; homologous to human CHAC and COH1 which are
involved in chorea acanthocytosis and Cohen syndrome,
respectively"
/codon_start=1
/product="Vps13p"
/protein_id="NP_013060.1"
/db_xref="GI:6322988"
/db_xref="SGD:S000003963"
/db_xref="GeneID:850619"
/translation="MLESLAANLLNRLLGSYVENFDPNQLNVGIWSGDVKLKNLKLRK
DCLDSLNLPIDVKSGILGDLVLTVPWSSLKNKPVKIIIEDCYLLCSPRSEDHENDEEM
IKRAFRLKMRKVSEWELTNQARILSTQSENKTSSSSSEKNNAGFMQSLTTKIIDNLQV
TIKNIHLRYEDMDGIFTTGPSSVGLTLNELSAVSTDSNWAPSFIDITQNITHKLLTLN
SLCLYWNTDSPPLISDDDQDRSLENFVRGFKDMIASKNSTAPKHQYILKPVSGLGKLS
INKLGSTEEQPHIDLQMFYDEFGLELDDTEYNDILHVLSSIQLRQITKKFKKARPSFA
VSENPTEWFKYIAACVINEIHEKNKMWTWESMKEKCEQRRLYTKLWVEKLKLKNLEAP
LRDPIQEAQLSELHKDLTYDEIILFRSVAKRQYAQYKLGMTEDSPTPTASSNIEPQTS
NKSATKNNGSWLSSWWNGKPTEEVDEDLIMTEEQRQELYDAIEFDENEDKGPVLQVPR
ERVELRVTSLLKKGSFTIRKKKQNLNLGSIIFENCKVDFAQRPDSFLSSFQLNKFSLE
DGSPNALYKHIISVRNSSKDQSSIDNHATGEEEEEDEPLLRASFELNPLDGLADSNLN
IKLLGMTVFYHVHFITEVHKFFKASNQHMETIGNIVNAAEATVEGWTTQTRMGIESLL
EDHKTVNVSLDLQAPLIILPLDPHDWDTPCAIIDAGHMSILSDLVPKEKIKEIKELSP
EEYDKIDGNEINRLMFDRFQILSQDTQIFVGPDIQSTIGKINTASSTNDFRILDKMKL
ELTVDLSILPKAYKLPTIRVFGHLPRLSLSINDIQYKTIMNLIANSIPSMIDDEENNG
DYVNYSSGSEKEMKKQIQLQLKNTLKALENMQPLQIEQKFLELHFDIDQAKIAFFQCI
KNDSRNSEKLVDILCQRLNFNFDKRAKEMNLDLRVHSLDVEDYIELTDNKEFKNLISS
GVEKVTRSQKDLFTLKYKRVQRIVPHNDTLIELFDQDIVMHMSELQLVLTPRSVLTLM
NYAMLTFTDPNAPEMPADVLRHNKEDRDDAPQKINMKIKMEAVNVIFNDDSIKLATLV
LSAGEFTMVLLPERYNINLKLGGLELTDETNESFSRDSVFRKIIQMKGQELVELSYES
FDPATNTKDYDSFLKYSTGSMHVNFIESAVNRMVNFFAKFQKSKVSFDRARLAAYNQA
PSIDAVNNMKMDIVIKAPIIQFPKLVGTQENNYDTMRFYLGEFFIENKFSVIDESHKI
NHIKLGVREGQLSSNLNFDGSSQQLYLVENIGLLFNIDRDPLPQDDTPELKVTSNFES
FALDLTENQLTYLLEISNKVSSAFNITDENSGESGGKGEIKSPSPDPASLSSESERTA
TPQSLQGSNKSNIKNPEQKYLDFSFKAPKIALTLYNKTKGVTSLNDCGLTRIMFQDIG
CSLGLKNDGTVDGQAHVAAFRIEDVRNIKDNKHTELIPKSKNKEYQFVANISRKNLEV
GRLLNISMTMDSPKMILAMDYLVSLKEFFDAIMSKSHENNLYYPENTNQKPENKAIVE
SVQEGGDVTKIQYSVNIIETALILLADPCDMNSEAISFKIGQFLVTDQNIMTVAANNV
GIFLFKMNSSEEKLRLLDDFSSSLTIDKRNSTPQTLMTNIQLSVQPLLMRISLRDIRL
AMLIFKRVTTLLNKMTEKEDNGEEEESTDKIQFSHEFERKLAVLDPSILGERSRASQS
SDSESIEVPTAILKNETFNADLGGLRFILIGDVHEMPILDMNVNEITASAKDWSTDFE
ALASLETYVNIFNYSRSSWEPLLEMIPITFHLSKGHSEMDPAFSFDILTQRIAEITLS
ARSIAMLSHIPASLTEELPLASRVSQKPYQLVNDTELDFDVWIQDKTTEDNKNEVVLL
KANTSLPWEFEDWRSIREKLDIDKSKNILGVCVSGQNYKTIMNIDATTEGENLHVLSP
PRNNVHNRIVCEARCDENNVKIITFRSTLVIENTTSTEIELLVDSKDPNKPSLKYAIK
PHQSKSVPVEYAYDSDIRIRPASEDIYDWSQQTLSWKSLLSNQMSIFCSSKEDSNQRF
HFEIGAKYDEREPLAKIFPHMKIVVSASMTIENLLPADINFSIFDKREEKRTDFLKTG
ESMEVHHISLDSFLLMSVQPLQDEASASKPSIVNTPHKSPLNPEDSLSLTLSGGQNLL
LKLDYKNIDGTRSKVIRIYSPYIIMNSTDRELYIQSSLLNIAQSKILLENEKRYTIPK
MFSFDKEDDKSNRARIRFKESEWSSKLSFDAIGQSFDASVRIKNKEQESNLGINISEG
KGKYLLSKVIEIAPRYIISNTLDIPIEVCETGSMDVQQIESNITKPLYRMRNIVDKQL
VLKFLGGDSNWSQPFFIKNVGVTYLKVLKNSRHKLLKIEILLDKATIFIRIKDGGDRW
PFSIRNFSDHDFIFYQRDPRKVSDPYKDDQSNESSSRSFKPIFYRIPSKSIMPYAWDF
PTAKEKYLVLESGTRTREVRLAEIGELPPLRLDKRSKDKPAPIVGLHVVADDDMQALV
IVNYKANVGLYKLKTASATTTSSVSVNSSVTDGFVQKDEDEKVNTQIVVSFKGVGISL
INGRLQELLYINMRGIELRYNESKAYQTFSWKMKWMQIDNQLFSGNYSNILYPTEIPY
TEKEIENHPVISGSISKVNDSLQAVPYFKHVTLLIQEFSIQLDEDMLYAMMDFIKFPG
SPWIMDSRDYKYDEEIQLPDVSELKTAGDIYFEIFHIQPTVLHLSFIRSDEISPGLAE
ETEESFSSSLYYVHMFAMTLGNINEAPVKVNSLFMDNVRVPLPILMDHIERHYTTQFV
YQIHKILGSADCFGNPVGLFNTISSGVWDLFYEPYQGYMMNDRPQEIGIHLAKGGLSF
AKKTVFGLSDSMSKFTGSMAKGLSVTQDLEFQRVRRLQQRINKNNRNALANSAQSFAS
TLGSGLSGIALDPYKAMQKEGAAGFLKGLGKGIVGLPTKTAIGFLDLTSNLSQGVKST
TTVLDMQKGCRVRLPRYVDHDQIIKPYDLREAQGQYWLKTVNGGVFMNDEYLSHVILP
GKELAVIVSMQHIAEVQMATQELMWSTGYPSIQGITLERSGLQIKLKSQSEYFIPISD
PEERRSLYRNIAIAVREYNKYCEAIL"
gene complement(64062..65207)
/gene="UBI4"
/locus_tag="YLL039C"
/gene_synonym="SCD2; UB14"
/db_xref="GeneID:850620"
mRNA complement(64062..65207)
/gene="UBI4"
/locus_tag="YLL039C"
/gene_synonym="SCD2; UB14"
/product="ubiquitin"
/transcript_id="NM_001181859.1"
/db_xref="GI:296146503"
/db_xref="GeneID:850620"
CDS complement(64062..65207)
/gene="UBI4"
/locus_tag="YLL039C"
/gene_synonym="SCD2; UB14"
/note="Ubiquitin; becomes conjugated to proteins, marking
them for selective degradation via the ubiquitin-26S
proteasome system; essential for the cellular stress
response; encoded as a polyubiquitin precursor comprised
of 5 head-to-tail repeats; protein abundance increases in
response to DNA replication stress"
/codon_start=1
/product="ubiquitin"
/protein_id="NP_013061.1"
/db_xref="GI:6322989"
/db_xref="SGD:S000003962"
/db_xref="GeneID:850620"
/translation="MQIFVKTLTGKTITLEVESSDTIDNVKSKIQDKEGIPPDQQRLI
FAGKQLEDGRTLSDYNIQKESTLHLVLRLRGGMQIFVKTLTGKTITLEVESSDTIDNV
KSKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGGMQIFVKTL
TGKTITLEVESSDTIDNVKSKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKEST
LHLVLRLRGGMQIFVKTLTGKTITLEVESSDTIDNVKSKIQDKEGIPPDQQRLIFAGK
QLEDGRTLSDYNIQKESTLHLVLRLRGGMQIFVKTLTGKTITLEVESSDTIDNVKSKI
QDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGGN"
gene complement(65775..66518)
/gene="ENT4"
/locus_tag="YLL038C"
/db_xref="GeneID:850621"
mRNA complement(65775..66518)
/gene="ENT4"
/locus_tag="YLL038C"
/product="Ent4p"
/transcript_id="NM_001181858.1"
/db_xref="GI:296146504"
/db_xref="GeneID:850621"
CDS complement(65775..66518)
/gene="ENT4"
/locus_tag="YLL038C"
/note="hypothetical protein, contains an N-terminal
epsin-like domain; proposed to be involved in the
trafficking of Arn1p in the absence of ferrichrome"
/codon_start=1
/product="Ent4p"
/protein_id="NP_013062.1"
/db_xref="GI:6322990"
/db_xref="SGD:S000003961"
/db_xref="GeneID:850621"
/translation="MPLLDTFKSFIQSPTESKVKQATNEDETSGATGTLMNEISILTY
SPKTVREIIQVIRKRLLLGQNRRNSHRNCIQVMKTLTLVSYLMNNGSNEFIKWLKGNM
ILIEILEDFQVQDPRDERKAEDIQKLSRNVLGLLQDDGLLEKQRKDVIQFRSSISTPG
RKSTDNSHLKLEEMRSELTRQSLEKKAKPPTTSTSLDFQRQRTRNTHEYARFSLDPLA
EEDSEDTPGVAGGISKLSFRPKSSNNPFR"
gene complement(66745..68256)
/gene="PRP19"
/locus_tag="YLL036C"
/gene_synonym="PSO4"
/db_xref="GeneID:850623"
mRNA complement(66745..68256)
/gene="PRP19"
/locus_tag="YLL036C"
/gene_synonym="PSO4"
/product="E3 ubiquitin-protein ligase PRP19"
/transcript_id="NM_001181856.1"
/db_xref="GI:296146505"
/db_xref="GeneID:850623"
CDS complement(66745..68256)
/gene="PRP19"
/locus_tag="YLL036C"
/gene_synonym="PSO4"
/note="Splicing factor associated with the spliceosome;
contains a U-box, a motif found in a class of ubiquitin
ligases, and a WD40 domain"
/codon_start=1
/product="E3 ubiquitin-protein ligase PRP19"
/protein_id="NP_013064.1"
/db_xref="GI:6322992"
/db_xref="SGD:S000003959"
/db_xref="GeneID:850623"
/translation="MLCAISGKVPRRPVLSPKSRTIFEKSLLEQYVKDTGNDPITNEP
LSIEEIVEIVPSAQQASLTESTNSATLKANYSIPNLLTSLQNEWDAIMLENFKLRSTL
DSLTKKLSTVMYERDAAKLVAAQLLMEKNEDSKDLPKSSQQAVAITREEFLQGLLQSS
RDFVARGKLKAPKWPILKNLELLQAQNYSRNIKTFPYKELNKSMYYDKWVCMCRCEDG
ALHFTQLKDSKTITTITTPNPRTGGEHPAIISRGPCNRLLLLYPGNQITILDSKTNKV
LREIEVDSANEIIYMYGHNEVNTEYFIWADNRGTIGFQSYEDDSQYIVHSAKSDVEYS
SGVLHKDSLLLALYSPDGILDVYNLSSPDQASSRFPVDEEAKIKEVKFADNGYWMVVE
CDQTVVCFDLRKDVGTLAYPTYTIPEFKTGTVTYDIDDSGKNMIAYSNESNSLTIYKF
DKKTKNWTKDEESALCLQSDTADFTDMDVVCGDGGIAAILKTNDSFNIVALTP"
gene 68580..70478
/gene="GRC3"
/locus_tag="YLL035W"
/db_xref="GeneID:850624"
mRNA 68580..70478
/gene="GRC3"
/locus_tag="YLL035W"
/product="Grc3p"
/transcript_id="NM_001181855.1"
/db_xref="GI:296146506"
/db_xref="GeneID:850624"
CDS 68580..70478
/gene="GRC3"
/locus_tag="YLL035W"
/note="Polynucleotide kinase present on rDNA that is
required for efficient transcription termination by RNA
polymerase I; required for cell growth; mRNA is cell-cycle
regulated"
/codon_start=1
/product="Grc3p"
/protein_id="NP_013065.1"
/db_xref="GI:6322993"
/db_xref="SGD:S000003958"
/db_xref="GeneID:850624"
/translation="MVIDSKQDLPQYTKDSGSESDSDSSNNFIVESPSIPSSKSATVV
LNSEEYEDDEGDDLNGLDAELIDNITYEGDEDETMFVGLKEKQKLHLSGVFRLQVVKG
GIVYNNVHYNASREILTFWHPLSQSIPTIDFSHFAGWQDTFFMPRNNRFKIRDEEFKS
FPCVLRVFNSNHTGLLEAGHLYRDVNYLWKPKEPYFPLNERTTYHLLHESDRIQSLSV
PGYWSTPLEKLYLSHKNAAYDTRIMVIGGKNSGKSTFLRLLLEKFTQDIRDSTTSQEE
LVYLDLDPGQPEYSLPDSISLNKILSSPISLGQHLCQGSNFQTLLQFYAGSSSPQDEP
TSYLNCADKLIDHLEEQAFFGTSLLNLPGWIKGFGMQILNHIIRKYKPTHLLFLETAN
SKRHLDELTIPQSFSTSLRDAYAPEVVRVPAHSLNHTLSSRFHASQLRTFKILALFHK
ITQFDYDFAPLLKSAPLQISYGKGKSGIKGIQFPMEFQDLNPQDIKSALEGTVIGIYT
YSGEDSLEVKSLNTFPILQSCTSSSKNFITLGLIHSIDTSQQIMNIYVPPCHTQILDK
QPEDAQWIIVRNKTETPFCDFLPSPRTITWDDNIQIPFATFERRKKLEHVWKVRKNVM
RRGQFMKR"
gene complement(70633..73146)
/gene="RIX7"
/locus_tag="YLL034C"
/db_xref="GeneID:850625"
mRNA complement(70633..73146)
/gene="RIX7"
/locus_tag="YLL034C"
/product="putative AAA family ATPase RIX7"
/transcript_id="NM_001181854.1"
/db_xref="GI:296146507"
/db_xref="GeneID:850625"
CDS complement(70633..73146)
/gene="RIX7"
/locus_tag="YLL034C"
/note="Putative ATPase of the AAA family, required for
export of pre-ribosomal large subunits from the nucleus;
distributed between the nucleolus, nucleoplasm, and
nuclear periphery depending on growth conditions"
/codon_start=1
/product="putative AAA family ATPase RIX7"
/protein_id="NP_013066.1"
/db_xref="GI:6322994"
/db_xref="SGD:S000003957"
/db_xref="GeneID:850625"
/translation="MVKVKSKKNSLTSSLDNKIVDLIYRLLEEKTLDRKRSLRQESQG
EEGENNEGEEDEDIFESMFFAKDLTAGEIFTFCLTKDLSLQRVKKVVLQKTIDRMLKD
VIESELEEFGSYPGYNNEEEEKPSLEEELAKKNMMIERDTNEMNKRITSTWSKSGSVS
ESITETDDPKTEEVKKSKKRSKEGTCKVKRQKIKEDRSPPNSSLKSLGGMDDVVAQLM
ELIGLPILHPEIFLSTGVEPPRGVLLHGPPGCGKTSIANALAGELQVPFISISAPSVV
SGMSGESEKKIRDLFDEARSLAPCLVFFDEIDAITPKRDGGAQREMERRIVAQLLTSM
DELTMEKTNGKPVIIIGATNRPDSLDAALRRAGRFDREICLNVPNEVSRLHILKKMSD
NLKIDGAIDFAKLAKLTPGFVGADLKALVTAAGTCAIKRIFQTYANIKSTPTTATDSS
EDNMEIDETANGDESSLKNTANMIDPLPLSVVQQFIRNYPEPLSGEQLSLLSIKYEDF
LKALPTIQPTAKREGFATVPDVTWANVGALQRVRLELNMAIVQPIKRPELYEKVGISA
PGGVLLWGPPGCGKTLLAKAVANESRANFISIKGPELLNKYVGESERSIRQVFTRARA
SVPCVIFFDELDALVPRRDTSLSESSSRVVNTLLTELDGLNDRRGIFVIGATNRPDMI
DPAMLRPGRLDKSLFIELPNTEEKLDIIKTLTKSHGTPLSSDVDFEEIIRNEKCNNFS
GADLAALVRESSVLALKRKFFQSEEIQSVLDNDLDKEFEDLSVGVSGEEIIVTMSDFR
SALRKIKPSVSDKDRLKYDRLNKKMGLTEEMKDAEEMKQ"
gene 73409..74101
/gene="IRC19"
/locus_tag="YLL033W"
/gene_synonym="RRG4"
/db_xref="GeneID:850626"
mRNA 73409..74101
/gene="IRC19"
/locus_tag="YLL033W"
/gene_synonym="RRG4"
/product="Irc19p"
/transcript_id="NM_001181853.1"
/db_xref="GI:296146508"
/db_xref="GeneID:850626"
CDS 73409..74101
/gene="IRC19"
/locus_tag="YLL033W"
/gene_synonym="RRG4"
/note="hypothetical protein; YLL033W is not an essential
gene but mutant is defective in spore formation; null
mutant displays increased levels of spontaneous Rad52p
foci"
/codon_start=1
/product="Irc19p"
/protein_id="NP_013067.1"
/db_xref="GI:6322995"
/db_xref="SGD:S000003956"
/db_xref="GeneID:850626"
/translation="MRKPSITITTAKAIITPDYTLIKSHSKYQLPSRFQKLDADSPER
STVVKLFYRRFMRLKPFISNVKMVKDTYRDYVRYKFMKENYELKRYLVFNPDGLRSKI
NLELLSNTKCCERILPVTEMQRTLEFVLKSCSYLPETKVQKWDIARDNTYCRQILKNL
LTMQYEKYRSILHRGIGHDELDVKFSHLKTTSSPLTKLNKTEKKKIPLFKVFSDFDTT
LIYLNETLGTRL"
gene complement(74270..76747)
/locus_tag="YLL032C"
/db_xref="GeneID:850627"
mRNA complement(74270..76747)
/locus_tag="YLL032C"
/product="hypothetical protein"
/transcript_id="NM_001181852.1"
/db_xref="GI:296146509"
/db_xref="GeneID:850627"
CDS complement(74270..76747)
/locus_tag="YLL032C"
/note="hypothetical protein that may interact with
ribosomes, based on co-purification experiments; green
fluorescent protein (GFP)-fusion protein localizes to the
cytoplasm; YLL032C is not an essential gene"
/codon_start=1
/product="hypothetical protein"
/protein_id="NP_013068.1"
/db_xref="GI:6322996"
/db_xref="SGD:S000003955"
/db_xref="GeneID:850627"
/translation="MDNFKIYSTVITTAFLQVPHLYTTNRLWKPIEAPFLVEFLQKRI
SSKELKNTKAICHIDPSWVNLNASFIRDDMISIKATTDDMDLDAICRISLPLPMNTND
LTAELEKMKRILLDLSEKFNLELIITKEPAYFTPEQTGESKELCIYVHALGFRSNLME
CEPQLLAFVDLIKKNGMTLPPQHYIIEPMELNSYSVLPLYMGVDMENFKHISRAFKTS
IYAPSLITLSRDLKANPQIFFSGAVHSLSLLARKTLRESISVNSKSFFYRRLTNITPG
KLLFIRKYYQQKVNQLILKYQSLIRVTNEYIEFQSISTNLLEMVIKNFTIQVLHEIVE
VQISLNENCAMSPELIIDSFFGHTGNQIVVITPKEDSFNQLIVVGNQSSTDEASDTSI
LHYLSDFIMGSNQVINPNLRQIKAIFEIHPDFEDFISGKKNGKLTRIMELSACLIQLE
MEEEDDNLYLNLVSDSFPDFKESFKNVINEFPAEESFFIPEVCHRPIIGTGGSLIQAT
MRKHNVFIQFSNSFNLPQNKISMIRYDNVIIRCPRKNKANICLAKNDLKQIVQEYDSL
QSKTLIRFSSGQYRHILHVNGQKNIIGQIEKNENVYIMIPLKEPLDGTSQLSIQGNDE
NASRAANELVNSAFGYEYEFKIDQEIDPNKEYEFYNLIVVPFLQIMNIIVTFEKDLIT
FTFEKDTNENTLTKAIELLSNYLETQKTKIIFKKIIKKFVLGSASSKSNTSNSNTNGN
FRSMNNAKSRTTIDNTSQSGASPQRHKMPVITTVGGAQAIKGYIPNTYYNGYGYGYGY
TYEYDYNYANSNKAQTNNRHKYQNGRK"
gene complement(77152..80205)
/gene="GPI13"
/locus_tag="YLL031C"
/gene_synonym="MPC1"
/db_xref="GeneID:850628"
mRNA complement(77152..80205)
/gene="GPI13"
/locus_tag="YLL031C"
/gene_synonym="MPC1"
/product="Gpi13p"
/transcript_id="NM_001181851.1"
/db_xref="GI:296146510"
/db_xref="GeneID:850628"
CDS complement(77152..80205)
/gene="GPI13"
/locus_tag="YLL031C"
/gene_synonym="MPC1"
/EC_number="2.-.-.-"
/note="ER membrane localized phosphoryltransferase that
adds phosphoethanolamine onto the third mannose residue of
the glycosylphosphatidylinositol (GPI) anchor precursor;
similar to human PIG-O protein"
/codon_start=1
/product="Gpi13p"
/protein_id="NP_013069.1"
/db_xref="GI:6322997"
/db_xref="SGD:S000003954"
/db_xref="GeneID:850628"
/translation="MDEKTIKKSILSSSNDEKIIYKSRIKKFQKNHKFYIILLVFIAI
LQFISIAFFTRGFLLSRHVLDNISSQNETSKLPPRFNKAVILVIDALRFDFAIPVNES
HSNYNLNYHNNILSLYDSFASDKDASSLLLKFIADPPTTTLQRLKGLTTGSLPTFIDA
GSNFDGTVIEEDNFLKQLHLANKTVKFAGDDTWMALFHPFLSNDSFPLESLNVWDLDT
VDNGVMDYFHDHLQQDKEWDVMIGHMLGIDHVGHKYGPDHFTMREKQIQVDQFIDWIL
KSIDDDTLLVILGDHGMDHTGNHGGDSIDELESTLFLYSKKPDMWRLKETSNYNIDNL
GHDYRSVRQIDLVSSLALLMGQPIPFNNLGWPIDEIARNDREWSQFVNSAISQLQLYK
DTMQIHHGNDEILEPLAKNISNTPPTSDPEKFVKLGHKYQKVFLQTCEELWAKFDYYS
IATGITLLATSLVLLISITKLIPSIVVNQMVPEFVPGIIIMVLVTNLCFHGIFYVYQQ
PSFVDQFWGTLLATAIGIIIGCYITIFDRYNFIWIAMRLGETLADYWSRIAVMFMIIH
ALLFTSNSFTIWEDRIVAFLLSTFGMLTLYEFVFLPKRQSTTALLTATISEKEGTTSG
VNPSTANSNYLPLTRFARLLGGYHSAVLIIFTRLASMITICREEQGEYCIPTFNNQNN
SSWWVLGLCFLMIFILPACITGYYNLTSSYQAAAPIWINVFLKGILGLNFVYWSLTSL
ENNSAVIAIPFLRDVTIFKFTLARIIAGFSLIASNVGWLMGPLCIKLNIHNTDVKSHE
ATILGYTNIYGSEFFLLVINVLISILLFNKPLAQLSYFLMCNQLLSILEIIDLLKLKE
NIIGPIALGLLSYQHFFTTGHQATIPSVQWDIGFMLSEKVTFPFTQIAIILNTFGPHI
LVSLSVALLTLWSQPPDVLKPQTLLGRIVSNCGILLTYNTILCLSSFIWVTHFRRHLM
VWKIFCPRFIFASLSLIVTQLVVTFGTIAFASGRLIKHINDIFWK"
gene 81461..83710
/gene="FRA1"
/locus_tag="YLL029W"
/db_xref="GeneID:850630"
mRNA 81461..83710
/gene="FRA1"
/locus_tag="YLL029W"
/product="Fra1p"
/transcript_id="NM_001181849.1"
/db_xref="GI:296146511"
/db_xref="GeneID:850630"
CDS 81461..83710
/gene="FRA1"
/locus_tag="YLL029W"
/EC_number="3.4.11.9"
/note="Protein involved in negative regulation of
transcription of iron regulon; forms an iron independent
complex with Fra2p, Grx3p, and Grx4p; cytosolic; mutant
fails to repress transcription of iron regulon and is
defective in spore formation"
/codon_start=1
/product="Fra1p"
/protein_id="NP_013071.1"
/db_xref="GI:6322999"
/db_xref="SGD:S000003952"
/db_xref="GeneID:850630"
/translation="MTSKPSTSDGRAHSISHVPGTHMRGTSASHSPRPFRPCADCTCS
PGLLSRQGRRASLFLRQLENSRRSSSMLLNELKGAGGGSSAGNGSVYSCDSLCAVNRE
VNTTDRLLKLRQEMKKHDLCCYIVPSCDEHQSEYVSLRDQRRAFISGFSGSAGVACIT
RDLLNFNDDHPDGKSILSTDGRYFNQARQELDYNWTLLRQNEDPITWQEWCVREALEM
AKGLGNKEGMVLKIGIDPKLITFNDYVSFRKMIDTKYDAKGKVELVPVEENLVDSIWP
DFETLPERPCNDLLLLKYEFHGEEFKDKKEKLLKKLNDKASSATTGRNTFIVVALDEI
CWLLNLRGSDIDYNPVFFSYVAINEDETILFTNNPFNDDISEYFKINGIEVRPYEQIW
EHLTKITSQASSAEHEFLIPDSASWQMVRCLNTSTNANGAIAKKMTAQNFAIIHSPID
VLKSIKNDIEIKNAHKAQVKDAVCLVQYFAWLEQQLVGREALIDEYRAAEKLTEIRKT
QRNFMGNSFETISSTGSNAAIIHYSPPVENSSMIDPTKIYLCDSGSQFLEGTTDITRT
IHLTKPTKEEMDNYTLVLKGGLALERLIFPENTPGFNIDAIARQFLWSRGLDYKHGTG
HGIGSFLNVHEGPMGVGFRPHLMNFPLRAGNIISNEPGYYKDGEYGIRIESDMLIKKA
TEKGNFLKFENMTVVPYCRKLINTKLLNEEEKTQINEYHARVWRTIVHFLQPQSISYK
WLKRETSPL"
gene 84804..86564
/gene="TPO1"
/locus_tag="YLL028W"
/db_xref="GeneID:850631"
mRNA 84804..86564
/gene="TPO1"
/locus_tag="YLL028W"
/product="Tpo1p"
/transcript_id="NM_001181848.1"
/db_xref="GI:296146512"
/db_xref="GeneID:850631"
CDS 84804..86564
/gene="TPO1"
/locus_tag="YLL028W"
/note="Polyamine transporter of the major facilitator
superfamily; member of the 12-spanner drug:H(+) antiporter
DHA1 family; recognizes spermine, putrescine, and
spermidine; catalyzes uptake of polyamines at alkaline pH
and excretion at acidic pH; phosphorylation enhances
activity and sorting to the plasma membrane"
/codon_start=1
/product="Tpo1p"
/protein_id="NP_013072.1"
/db_xref="GI:6323000"
/db_xref="SGD:S000003951"
/db_xref="GeneID:850631"
/translation="MSDHSPISNKENHLLPSDSSRSSSSDMHSTGTTGTTGVEPVDFT
GEGAKYTTATEGNGGADLAIQRTTTMNSAAESEVNITRRLTKILTGSVNEPDRVEVDY
TNCAPMGGDRPYPPSLPSRDLYEVTFDGPNDPLHPFNWPMKKKVLLCLVLCLDSIAIA
MCSSIFASAVPQICEIYHVIEVVAILGITLFVLGFAASPVIYAPLSELYGRKGVLVLS
AFGFALFQFAVATAENLQTIFICRFFGGFIGAAPMAVVPAAFADMFDTNVRGKAIALF
SLGVFVGPILSPVMGSYIAQRTTWRWLEYVVGCFASAVFVAIVLFFEETHHPTILVNK
AKQMRKQSNNWGIHAAHEDVELSIKDIVQKTVTRPIIMLFVEPLLLFVTIYNSFVYGI
LYLLLEAYPLVFVEGYGFTENGELPYIALIIGMMVCAAFIWYMDNDYLKRCRAKGKLV
PEARLYAMVIAGTVFPIGILWFCWTGYYPHKIHWMVPTVGGAFIGFGLMGIFLPCLNY
IIESYLLLAASAVAANTFMRSAFGACFPLFAGYMFRGMGIGWAGLLLGLFAAAMIPVP
LLFLKYGESIRKKSKYAYAA"
gene 87403..88155
/gene="ISA1"
/locus_tag="YLL027W"
/db_xref="GeneID:850632"
mRNA 87403..88155
/gene="ISA1"
/locus_tag="YLL027W"
/product="Isa1p"
/transcript_id="NM_001181847.1"
/db_xref="GI:296146513"
/db_xref="GeneID:850632"
CDS 87403..88155
/gene="ISA1"
/locus_tag="YLL027W"
/note="Protein required for maturation of mitochondrial
[4Fe-4S] proteins; functions in a complex with Isa2p and
possibly Iba57p; isa1 deletion causes loss of
mitochondrial DNA and respiratory deficiency; depletion
reduces growth on nonfermentable carbon sources;
functional ortholog of bacterial A-type ISC proteins"
/codon_start=1
/product="Isa1p"
/protein_id="NP_013073.1"
/db_xref="GI:6323001"
/db_xref="SGD:S000003950"
/db_xref="GeneID:850632"
/translation="MINTGRSRNSVLLAHRFLSTGGFWRGGTNGTMSRTINNVNPFKL
KFIPKTVPAAADSVSPDSQRPGKKPFKFIVSNQSKSSKASKSPKWSSYAFPSRETIKS
HEEAIKKQNKAIDEQIAAAVSKNDCSCTEPPKKRKRKLRPRKALITLSPKAIKHLRAL
LAQPEPKLIRVSARNRGCSGLTYDLQYITEPGKFDEVVEQDGVKIVIDSKALFSIIGS
EMDWIDDKLASKFVFKNPNSKGTCGCGESFMV"
gene 88623..91349
/gene="HSP104"
/locus_tag="YLL026W"
/db_xref="GeneID:850633"
mRNA 88623..91349
/gene="HSP104"
/locus_tag="YLL026W"
/product="Hsp104p"
/transcript_id="NM_001181846.1"
/db_xref="GI:296146514"
/db_xref="GeneID:850633"
CDS 88623..91349
/gene="HSP104"
/locus_tag="YLL026W"
/note="Disaggregase; heat shock protein that cooperates
with Ydj1p (Hsp40) and Ssa1p (Hsp70) to refold and
reactivate previously denatured, aggregated proteins;
responsive to stresses including: heat, ethanol, and
sodium arsenite; involved in [PSI+] propagation; protein
becomes more abundant and forms cytoplasmic foci in
response to DNA replication stress"
/codon_start=1
/product="chaperone ATPase HSP104"
/protein_id="NP_013074.1"
/db_xref="GI:6323002"
/db_xref="SGD:S000003949"
/db_xref="GeneID:850633"
/translation="MNDQTQFTERALTILTLAQKLASDHQHPQLQPIHILAAFIETPE
DGSVPYLQNLIEKGRYDYDLFKKVVNRNLVRIPQQQPAPAEITPSYALGKVLQDAAKI
QKQQKDSFIAQDHILFALFNDSSIQQIFKEAQVDIEAIKQQALELRGNTRIDSRGADT
NTPLEYLSKYAIDMTEQARQGKLDPVIGREEEIRSTIRVLARRIKSNPCLIGEPGIGK
TAIIEGVAQRIIDDDVPTILQGAKLFSLDLAALTAGAKYKGDFEERFKGVLKEIEESK
TLIVLFIDEIHMLMGNGKDDAANILKPALSRGQLKVIGATTNNEYRSIVEKDGAFERR
FQKIEVAEPSVRQTVAILRGLQPKYEIHHGVRILDSALVTAAQLAKRYLPYRRLPDSA
LDLVDISCAGVAVARDSKPEELDSKERQLQLIQVEIKALERDEDADSTTKDRLKLARQ
KEASLQEELEPLRQRYNEEKHGHEELTQAKKKLDELENKALDAERRYDTATAADLRYF
AIPDIKKQIEKLEDQVAEEERRAGANSMIQNVVDSDTISETAARLTGIPVKKLSESEN
EKLIHMERDLSSEVVGQMDAIKAVSNAVRLSRSGLANPRQPASFLFLGLSGSGKTELA
KKVAGFLFNDEDMMIRVDCSELSEKYAVSKLLGTTAGYVGYDEGGFLTNQLQYKPYSV
LLFDEVEKAHPDVLTVMLQMLDDGRITSGQGKTIDCSNCIVIMTSNLGAEFINSQQGS
KIQESTKNLVMGAVRQHFRPEFLNRISSIVIFNKLSRKAIHKIVDIRLKEIEERFEQN
DKHYKLNLTQEAKDFLAKYGYSDDMGARPLNRLIQNEILNKLALRILKNEIKDKETVN
VVLKKGKSRDENVPEEAEECLEVLPNHEATIGADTLGDDDNEDSMEIDDDLD"
rep_origin 91419..91660
/note="ARS1206;
Autonomously Replicating Sequence"
/db_xref="SGD:S000118469"
LTR complement(92050..92381)
/note="Ty1 LTR"
/db_xref="SGD:S000007064"
gene 92548..92650
/locus_tag="tP(UGG)L"
/db_xref="GeneID:850634"
tRNA join(92548..92583,92615..92650)
/locus_tag="tP(UGG)L"
/product="tRNA-Pro"
/note="Proline tRNA (tRNA-Pro), predicted by tRNAscan-SE
analysis; target of K. lactis zymocin"
/db_xref="SGD:S000006683"
/db_xref="GeneID:850634"
gene 94747..95121
/gene="PAU17"
/locus_tag="YLL025W"
/db_xref="GeneID:850635"
mRNA 94747..95121
/gene="PAU17"
/locus_tag="YLL025W"
/product="Pau17p"
/transcript_id="NM_001181845.1"
/db_xref="GI:296146515"
/db_xref="GeneID:850635"
CDS 94747..95121
/gene="PAU17"
/locus_tag="YLL025W"
/note="hypothetical protein, member of the seripauperin
multigene family encoded mainly in subtelomeric regions;
YLL025W is not an essential gene"
/codon_start=1
/product="Pau17p"
/protein_id="NP_013075.1"
/db_xref="GI:6323003"
/db_xref="SGD:S000003948"
/db_xref="GeneID:850635"
/translation="MVKLTSIAAGVAAIAAGVAAAPATTTLSPSDERVNLVELGVYVS
DIRAHLAEYYMFQAAHPTETYPVEIAEAVFNYGDFTTMLTGIPADQVTRVITGVPWYS
TRLRPAISSALSADGIYTAVPN"
gene complement(95566..97485)
/gene="SSA2"
/locus_tag="YLL024C"
/gene_synonym="YG102"
/db_xref="GeneID:850636"
mRNA complement(95566..97485)
/gene="SSA2"
/locus_tag="YLL024C"
/gene_synonym="YG102"
/product="Ssa2p"
/transcript_id="NM_001181844.1"
/db_xref="GI:296146516"
/db_xref="GeneID:850636"
CDS complement(95566..97485)
/gene="SSA2"
/locus_tag="YLL024C"
/gene_synonym="YG102"
/note="ATP binding protein involved in protein folding and
vacuolar import of proteins; member of heat shock protein
70 (HSP70) family; associated with the
chaperonin-containing T-complex; present in the cytoplasm,
vacuolar membrane and cell wall; 98% identical with Ssa1p,
but subtle differences between the two proteins provide
functional specificity with respect to propagation of
yeast [URE3] prions and vacuolar-mediated degradations of
gluconeogenesis enzymes"
/codon_start=1
/product="Hsp70 family chaperone SSA2"
/protein_id="NP_013076.1"
/db_xref="GI:6323004"
/db_xref="SGD:S000003947"
/db_xref="GeneID:850636"
/translation="MSKAVGIDLGTTYSCVAHFSNDRVDIIANDQGNRTTPSFVGFTD
TERLIGDAAKNQAAMNPANTVFDAKRLIGRNFNDPEVQGDMKHFPFKLIDVDGKPQIQ
VEFKGETKNFTPEQISSMVLGKMKETAESYLGAKVNDAVVTVPAYFNDSQRQATKDAG
TIAGLNVLRIINEPTAAAIAYGLDKKGKEEHVLIFDLGGGTFDVSLLSIEDGIFEVKA
TAGDTHLGGEDFDNRLVNHFIQEFKRKNKKDLSTNQRALRRLRTACERAKRTLSSSAQ
TSVEIDSLFEGIDFYTSITRARFEELCADLFRSTLDPVEKVLRDAKLDKSQVDEIVLV
GGSTRIPKVQKLVTDYFNGKEPNRSINPDEAVAYGAAVQAAILTGDESSKTQDLLLLD
VAPLSLGIETAGGVMTKLIPRNSTIPTKKSEVFSTYADNQPGVLIQVFEGERAKTKDN
NLLGKFELSGIPPAPRGVPQIEVTFDVDSNGILNVSAVEKGTGKSNKITITNDKGRLS
KEDIEKMVAEAEKFKEEDEKESQRIASKNQLESIAYSLKNTISEAGDKLEQADKDAVT
KKAEETIAWLDSNTTATKEEFDDQLKELQEVANPIMSKLYQAGGAPEGAAPGGFPGGA
PPAPEAEGPTVEEVD"
gene complement(97997..98836)
/gene="POM33"
/locus_tag="YLL023C"
/db_xref="GeneID:850637"
mRNA complement(97997..98836)
/gene="POM33"
/locus_tag="YLL023C"
/product="Pom33p"
/transcript_id="NM_001181843.1"
/db_xref="GI:296146517"
/db_xref="GeneID:850637"
CDS complement(97997..98836)
/gene="POM33"
/locus_tag="YLL023C"
/note="Transmembrane nucleoporin; involved in nuclear pore
complex (NPC) distribution, assembly or stabilization;
highly conserved across species, orthologous to human
TMEM33 and paralogous to Per33p; protein abundance
increases in response to DNA replication stress"
/codon_start=1
/product="Pom33p"
/protein_id="NP_013077.1"
/db_xref="GI:6323005"
/db_xref="SGD:S000003946"
/db_xref="GeneID:850637"
/translation="MSSRPANNQGPPNLPARDKSLVQRFMAVAKSLQFAWFTGHSVVL
ISSILYLLKMSEFYYRSAYLGVIESFGIIIYQQFFTRNEPLQTQDAAATKASIKSRVA
GLLKSEDVLYLVLANFWLFTPRFSFSLIPFFAFAVFHVLIYVEKVLLPKVFHLSSKDS
SKILSFIDKFVVQYNDLCMHWVGTAELLIFILVLFRAILCFQRSWIILVVYAIFIKLR
YENSKYMKAAFAQWRVRMDGIISHPSIPPFVKRAYNAIKMSLIRLSEYRLSGAPQVTK
KQN"
gene complement(99044..100201)
/gene="HIF1"
/locus_tag="YLL022C"
/db_xref="GeneID:850638"
mRNA complement(99044..100201)
/gene="HIF1"
/locus_tag="YLL022C"
/product="Hif1p"
/transcript_id="NM_001181842.1"
/db_xref="GI:296146518"
/db_xref="GeneID:850638"
CDS complement(99044..100201)
/gene="HIF1"
/locus_tag="YLL022C"
/note="Non-essential component of the HAT-B histone
acetyltransferase complex (Hat1p-Hat2p-Hif1p), localized
to the nucleus; has a role in telomeric silencing"
/codon_start=1
/product="Hif1p"
/protein_id="NP_013078.1"
/db_xref="GI:6323006"
/db_xref="SGD:S000003945"
/db_xref="GeneID:850638"
/translation="MKLRAEDVLANGTSRHKVQIDMERQVQIAKDLLAQKKFLEAAKR
CQQTLDSLPKDGLLPDPELFTIFAQAVYNMEVQNSGNLFGDALLAGDDGSGSESESEP
ESDVSNGEEGNENGQTEIPNSRMFQFDQEEEDLTGDVDSGDSEDSGEGSEEEEENVEK
EEERLALHELANFSPANEHDDEIEDVSQLRKSGFHIYFENDLYENALDLLAQALMLLG
RPTADGQSLTENSRLRIGDVYILMGDIEREAEMFSRAIHHYLKALGYYKTLKPAEQVT
EKVIQAEFLVCDALRWVDQVPAKDKLKRFKHAKALLEKHMTTRPKDSELQQARLAQIQ
DDIDEVQENQQHGSKRPLSQPTTSIGFPALEKPLGDFNDLSQLVKKKPRRH"
gene 100947..105347
/gene="SPA2"
/locus_tag="YLL021W"
/gene_synonym="FUS6; PEA1"
/db_xref="GeneID:850639"
mRNA 100947..105347
/gene="SPA2"
/locus_tag="YLL021W"
/gene_synonym="FUS6; PEA1"
/product="Spa2p"
/transcript_id="NM_001181841.1"
/db_xref="GI:296146519"
/db_xref="GeneID:850639"
CDS 100947..105347
/gene="SPA2"
/locus_tag="YLL021W"
/gene_synonym="FUS6; PEA1"
/note="Component of the polarisome, which functions in
actin cytoskeletal organization during polarized growth;
acts as a scaffold for Mkk1p and Mpk1p cell wall integrity
signaling components; potential Cdc28p substrate"
/codon_start=1
/product="Spa2p"
/protein_id="NP_013079.1"
/db_xref="GI:6323007"
/db_xref="SGD:S000003944"
/db_xref="GeneID:850639"
/translation="MGTSSEVSLAHHRDIFHYYVSLKTFFEVTGENRDRSNSTRAQKA
RAKLLKLSSSQFYELSTDVSDELQRRIGEDANQPDYLLPKANFHMKRNQARQKLANLS
QTRFNDLLDDILFEIKRRGFDKDLDAPRPPLPQPMKQEVSKDSDDTARTSTNSSSVTQ
VAPNVSVQPSLVIPKMASIDWSSEEEEEEQVKEKPNEPEGKQTSMDEKKEAKPALNPI
VTDSDLPDSQVLARDITSMARTPTTTHKNYWDVNDSPIIKVDKDIDNEKGPEQLKSPE
VQRAENNNPNSEMEDKVKELTDLNSDLHLQIEDLNAKLASLTSEKEKEKKEEKEEKEK
EKNLKINYTIDESFQKELLSLNSQIGELSIENENLKQKISEFELHQKKNDNHNDLKIT
DGFISKYSSADGLIPAQYILNANNLIIQFTTRLSAVPIGDSTAISHQIGEELFQILSQ
LSNLISQLLLSADLLQYKDQVILLKASLSHAITSIRYFSVYGPVLIPKITVQAAVSEV
CFAMCNLIDSAKIKSDSNGESTTSNEGNRQVLEYSSPTATTPMTPTFPSTSGINMKKG
FINPRKPASFLNDVEEEESPVKPLKITQKAINSPIIRPSSSNGVPTTSRKPSGTGLFS
LMIDSSIAKNSSHKEDNDKYVSPIKAVTSASNSASSNISEIPKLTLPPQAKIGTVIPP
SENQVPNIKIENTEEDNKRSDITNEISVKPTSSIADKLKQFEQSSEKKSSPKENPIAK
EEMDSKPKLSNKFITSMNDVSTDDSSSDGNENDDADDDDDFTYMALKQTMKREGSKIE
KNNDSKLPANIVELDLHESPESVKIESPESIKEITSSEMSSEMPSSSLPKRLVEDVEP
SEMPEKGASVESVRKKNFQEPLGNVESPDMTQKVKSLGMTGKAVGPESDSRVESPGMT
GQIKSLNMAGKVVGPEADSRVESPGMKEQIKSLGMTGKITAQESIKSPEAARKLASSG
EVDKIESPRMVRESESLEAVGNTIPSNMTVKMESPNLKGNTVSEPQEIRRDIASSEPI
ENVDPPKVLKKIVFPKAVNRTGSPKSVEKTPSSATLKKSGLPEPNSQIVSPELAKNSP
LAPIKKNVELRETNKPHTETITSVEPTNKDANTSWRDADLNRTIKREEEDEDFDRVNH
NIQITGAYTKTGKIDYHKIPVDRKAKSEAEVHTSEEDIDESNNVNGKRADAQIHITER
KHAFVNPTENSQVKKTSHSPFLNSKPVQYENSESNGGINNHIKIKNTGETTAHDEKHY
SDDDDSSYQFVPMKHEEQEQEQNRSEEEESEDDDEEEEDSDFDVDTFDIENPDNTLSE
LLLYLEHQTMDVISTIQSLLTSIKKPQVTKGNLRGESNAINQVIGQMVDATSISMEQS
RNANLKKHGDWVVQSLRDCSRRMTILCQLTGDGILAKEKSDQDYADKNFKQRLAGIAF
DVAKCTKELVKTVEEASLKDEINYLNSKLK"
gene complement(105686..107899)
/gene="KNS1"
/locus_tag="YLL019C"
/db_xref="GeneID:850641"
mRNA complement(105686..107899)
/gene="KNS1"
/locus_tag="YLL019C"
/product="Kns1p"
/transcript_id="NM_001181839.1"
/db_xref="GI:296146520"
/db_xref="GeneID:850641"
CDS complement(105686..107899)
/gene="KNS1"
/locus_tag="YLL019C"
/EC_number="2.7.12.1"
/note="Protein kinase involved in negative regulation of
PolIII transcription; effector kinase of the TOR signaling
pathway and phosphorylates Rpc53p to regulate ribosome and
tRNA biosynthesis; member of the LAMMER family of protein
kinases, which are serine/threonine kinases also capable
of phosphorylating tyrosine residues; capable of
autophosphorylation"
/codon_start=1
/product="Kns1p"
/protein_id="NP_013081.1"
/db_xref="GI:6323009"
/db_xref="SGD:S000003942"
/db_xref="GeneID:850641"
/translation="MSQNIQIGTRKRSRANMNNSTTTGPANNTSSNKTFLDNFEETRT
NKLLDEMFARQNSFLTDNLRNSLDLNQADNPLRPRQHQHQLFLDNENAIELDEEPRII
NTTINNSNNHNSSRVDEDADDDIIFIKEQPIQFSSPLILPSSSSINNNNNIVTSNNPG
CGTAATSNSTYITTPKKFKKQRTISLPQLPLSKLSYQSNYFNVPDQTNAIVPRVTQTE
NELLHLTGSCAKTLEGNKAVNLTIAHSTSPFSNPPAQIASLPQSNLKKQIGSSLRKFT
SNGSSESASSNKSNFKTDKDGHYVYQENDIFGSGGRFVVKDLLGQGTFGKVLKCIDNK
YEPNYVAVKVIRAVDRYREAAKTELRILQTILNNDPQGQFQCLLLRECFDYKNHICLV
TDLYGRSIYDFMCSNGIARFPGSHIQAIARQLIRSVCFLHDLGIIHTDLKPENILICD
ETHIAQKLPLKTVQSLSKRRREASKGKRKILKNPEIKIIDFGSAIFHYEYHPPVISTR
HYRAPEIVLGLGWSFPCDIWSIACVLVELVIGESLYPIHENLEHMAMMQRINGTPFPT
DIIDKMFYKSKHKLGNSPSDLNSTVIKHFDRKTLSLQWPEKNKRGDTITTEKSMKRVL
QSCDRLDIYISKVLKQDYGDSLSINWNLPPEKNWSLINSKLAWKRQTHSSSSSTTDEL
DKETFLFWYWFIDLLRKMFEFDPTKRITAKDALDHEWFNLGILDDGIATYNNTQG"
gene complement(108676..108972)
/gene="COX19"
/locus_tag="YLL018C-A"
/db_xref="GeneID:850642"
mRNA complement(108676..108972)
/gene="COX19"
/locus_tag="YLL018C-A"
/product="Cox19p"
/transcript_id="NM_001184338.1"
/db_xref="GI:296146521"
/db_xref="GeneID:850642"
CDS complement(108676..108972)
/gene="COX19"
/locus_tag="YLL018C-A"
/note="Protein required for cytochrome c oxidase assembly,
located in the cytosol and mitochondrial intermembrane
space; putative copper metallochaperone that delivers
copper to cytochrome c oxidase; contains twin
cysteine-x9-cysteine motifs"
/codon_start=1
/product="Cox19p"
/protein_id="NP_013082.1"
/db_xref="GI:6323010"
/db_xref="SGD:S000007245"
/db_xref="GeneID:850642"
/translation="MSGNPGSSLSALRPTPPERGSFPLDHDGECTKYMQEYLKCMQLV
QNENAMNCRLLAKDYLRCRMDHQLMDYDEWSHLGLPEDAPGNNGKTIKDATDNK"
gene complement(109902..111575)
/gene="DPS1"
/locus_tag="YLL018C"
/db_xref="GeneID:850643"
mRNA complement(109902..111575)
/gene="DPS1"
/locus_tag="YLL018C"
/product="aspartate--tRNA ligase DPS1"
/transcript_id="NM_001181838.1"
/db_xref="GI:296146522"
/db_xref="GeneID:850643"
CDS complement(109902..111575)
/gene="DPS1"
/locus_tag="YLL018C"
/EC_number="6.1.1.12"
/note="Aspartyl-tRNA synthetase, primarily cytoplasmic;
homodimeric enzyme that catalyzes the specific
aspartylation of tRNA(Asp); class II aminoacyl tRNA
synthetase; binding to its own mRNA may confer
autoregulation"
/codon_start=1
/product="aspartate--tRNA ligase DPS1"
/protein_id="NP_013083.1"
/db_xref="GI:6323011"
/db_xref="SGD:S000003941"
/db_xref="GeneID:850643"
/translation="MSQDENIVKAVEESAEPAQVILGEDGKPLSKKALKKLQKEQEKQ
RKKEERALQLEAEREAREKKAAAEDTAKDNYGKLPLIQSRDSDRTGQKRVKFVDLDEA
KDSDKEVLFRARVHNTRQQGATLAFLTLRQQASLIQGLVKANKEGTISKNMVKWAGSL
NLESIVLVRGIVKKVDEPIKSATVQNLEIHITKIYTISETPEALPILLEDASRSEAEA
EAAGLPVVNLDTRLDYRVIDLRTVTNQAIFRIQAGVCELFREYLATKKFTEVHTPKLL
GAPSEGGSSVFEVTYFKGKAYLAQSPQFNKQQLIVADFERVYEIGPVFRAENSNTHRH
MTEFTGLDMEMAFEEHYHEVLDTLSELFVFIFSELPKRFAHEIELVRKQYPVEEFKLP
KDGKMVRLTYKEGIEMLRAAGKEIGDFEDLSTENEKFLGKLVRDKYDTDFYILDKFPL
EIRPFYTMPDPANPKYSNSYDFFMRGEEILSGAQRIHDHALLQERMKAHGLSPEDPGL
KDYCDGFSYGCPPHAGGGIGLERVVMFYLDLKNIRRASLFPRDPKRLRP"
gene 112234..112545
/locus_tag="YLL017W"
/gene_synonym="SDC25"
/note="Non-essential Ras guanine nucleotide exchange
factor (GEF); localized to the membrane; expressed in poor
nutrient conditions and on nonfermentable carbon sources;
contains a stop codon in S288C, full-length gene includes
YLL016W; SDC25 has a paralog, CDC25, that arose from the
whole genome duplication"
/pseudo
/db_xref="GeneID:2827706"
/db_xref="SGD:S000003940"
mRNA 112234..112545
/locus_tag="YLL017W"
/gene_synonym="SDC25"
/pseudo
/db_xref="GeneID:2827706"
/db_xref="SGD:S000003940"
gene 112847..115993
/gene="SDC25"
/locus_tag="YLL016W"
/note="Non-essential Ras guanine nucleotide exchange
factor (GEF); localized to the membrane; expressed in poor
nutrient conditions and on nonfermentable carbon sources;
contains a stop codon in S288C, full-length gene includes
YLL017W; SDC25 has a paralog, CDC25, that arose from the
whole genome duplication"
/pseudo
/db_xref="GeneID:850644"
/db_xref="SGD:S000003939"
mRNA 112847..115993
/gene="SDC25"
/locus_tag="YLL016W"
/pseudo
/db_xref="GeneID:850644"
/db_xref="SGD:S000003939"
gene 116432..121111
/gene="BPT1"
/locus_tag="YLL015W"
/db_xref="GeneID:850645"
mRNA 116432..121111
/gene="BPT1"
/locus_tag="YLL015W"
/product="ATP-binding cassette bilirubin transporter BPT1"
/transcript_id="NM_001181835.1"
/db_xref="GI:296146523"
/db_xref="GeneID:850645"
CDS 116432..121111
/gene="BPT1"
/locus_tag="YLL015W"
/note="ABC type transmembrane transporter of MRP/CFTR
family, found in vacuolar membrane, involved in the
transport of unconjugated bilirubin and in heavy metal
detoxification via glutathione conjugates, along with
Ycf1p"
/codon_start=1
/product="ATP-binding cassette bilirubin transporter BPT1"
/protein_id="NP_013086.1"
/db_xref="GI:6323014"
/db_xref="SGD:S000003938"
/db_xref="GeneID:850645"
/translation="MSSLEVVDGCPYGYRPYPDSGTNALNPCFISVISAWQAVFFLLI
GSYQLWKLYKNNKVPPRFKNFPTLPSKINSRHLTHLTNVCFQSTLIICELALVSQSSD
RVYPFILKKALYLNLLFNLGISLPTQYLAYFKSTFSMGNQLFYYMFQILLQLFLILQR
YYHGSSNERLTVISGQTAMILEVLLLFNSVAIFIYDLCIFEPINELSEYYKKNGWYPP
VHVLSYITFIWMNKLIVETYRNKKIKDPNQLPLPPVDLNIKSISKEFKANWELEKWLN
RNSLWRAIWKSFGRTISVAMLYETTSDLLSVVQPQFLRIFIDGLNPETSSKYPPLNGV
FIALTLFVISVVSVFLTNQFYIGIFEAGLGIRGSLASLVYQKSLRLTLAERNEKSTGD
ILNLMSVDVLRIQRFFENAQTIIGAPIQIIVVLTSLYWLLGKAVIGGLVTMAIMMPIN
AFLSRKVKKLSKTQMKYKDMRIKTITELLNAIKSIKLYAWEEPMMARLNHVRNDMELK
NFRKIGIVSNLIYFAWNCVPLMVTCSTFGLFSLFSDSPLSPAIVFPSLSLFNILNSAI
YSVPSMINTIIETSVSMERLKSFLLSDEIDDSFIERIDPSADERALPAIEMNNITFLW
KSKEVLTSSQSGDNLRTDEESIIGSSQIALKNIDHFEAKRGDLVCVVGRVGAGKSTFL
KAILGQLPCMSGSRDSIPPKLIIRSSSVAYCSQESWIMNASVRENILFGHKFDQDYYD
LTIKACQLLPDLKILPDGDETLVGEKGISLSGGQKARLSLARAVYSRADIYLLDDILS
AVDAEVSKNIIEYVLIGKTALLKNKTIILTTNTVSILKHSQMIYALENGEIVEQGNYE
DVMNRKNNTSKLKKLLEEFDSPIDNGNESDVQTEHRSESEVDEPLQLKVTESETEDEV
VTESELELIKANSRRASLATLRPRPFVGAQLDSVKKTAQKAEKTEVGRVKTKIYLAYI
KACGVLGVVLFFLFMILTRVFDLAENFWLKYWSESNEKNGSNERVWMFVGVYSLIGVA
SAAFNNLRSIMMLLYCSIRGSKKLHESMAKSVIRSPMTFFETTPVGRIINRFSSDMDA
VDSNLQYIFSFFFKSILTYLVTVILVGYNMPWFLVFNMFLVVIYIYYQTFYIVLSREL
KRLISISYSPIMSLMSESLNGYSIIDAYDHFERFIYLNYEKIQYNVDFVFNFRSTNRW
LSVRLQTIGATIVLATAILALATMNTKRQLSSGMVGLLMSYSLEVTGSLTWIVRTTVT
IETNIVSVERIVEYCELPPEAQSINPEKRPDENWPSKGGIEFKNYSTKYRENLDPVLN
NINVKIEPCEKVGIVGRTGAGKSTLSLALFRILEPTEGKIIIDGIDISDIGLFDLRSH
LAIIPQDAQAFEGTVKTNLDPFNRYSEDELKRAVEQAHLKPHLEKMLHSKPRGDDSNE
EDGNVNDILDVKINENGSNLSVGQRQLLCLARALLNRSKILVLDEATASVDMETDKII
QDTIRREFKDRTILTIAHRIDTVLDSDKIIVLDQGSVREFDSPSKLLSDKTSIFYSLC
EKGGYLK"
gene 121322..121648
/gene="EMC6"
/locus_tag="YLL014W"
/db_xref="GeneID:850646"
mRNA 121322..121648
/gene="EMC6"
/locus_tag="YLL014W"
/product="Emc6p"
/transcript_id="NM_001181834.1"
/db_xref="GI:296146524"
/db_xref="GeneID:850646"
CDS 121322..121648
/gene="EMC6"
/locus_tag="YLL014W"
/note="Member of a transmembrane complex required for
efficient folding of proteins in the ER; null mutant
displays induction of the unfolded protein response"
/codon_start=1
/product="Emc6p"
/protein_id="NP_013087.1"
/db_xref="GI:6323015"
/db_xref="SGD:S000003937"
/db_xref="GeneID:850646"
/translation="MSSNEEVFTQINATANVVDNKKRLLFVQDSSALVLGLVAGFLQI
ESVHGFIWFLILYNLINVIYIVWICQLQPGKFYQSPLHDIFFESFFREITGFVMAWTF
GYALIG"
gene complement(122075..124714)
/gene="PUF3"
/locus_tag="YLL013C"
/db_xref="GeneID:850647"
mRNA complement(122075..124714)
/gene="PUF3"
/locus_tag="YLL013C"
/product="Puf3p"
/transcript_id="NM_001181833.1"
/db_xref="GI:296146525"
/db_xref="GeneID:850647"
CDS complement(122075..124714)
/gene="PUF3"
/locus_tag="YLL013C"
/note="Protein of the mitochondrial outer surface, links
the Arp2/3 complex with the mitochore during anterograde
mitochondrial movement; also binds to and promotes
degradation of mRNAs for select nuclear-encoded
mitochondrial proteins"
/codon_start=1
/product="Puf3p"
/protein_id="NP_013088.1"
/db_xref="GI:6323016"
/db_xref="SGD:S000003936"
/db_xref="GeneID:850647"
/translation="MEMNMDMDMDMELASIVSSLSALSHSNNNGGQAAAAGIVNGGAA
GSQQIGGFRRSSFTTANEVDSEILLLHGSSESSPIFKKTALSVGTAPPFSTNSKKFFG
NGGNYYQYRSTDTASLSSASYNNYHTHHTAANLGKNNKVNHLLGQYSASIAGPVYYNG
NDNNNSGGEGFFEKFGKSLIDGTRELESQDRPDAVNTQSQFISKSVSNASLDTQNTFE
QNVESDKNFNKLNRNTTNSGSLYHSSSNSGSSASLESENAHYPKRNIWNVANTPVFRP
SNNPAAVGATNVALPNQQDGPANNNFPPYMNGFPPNQFHQGPHYQNFPNYLIGSPSNF
ISQMISVQIPANEDTEDSNGKKKKKANRPSSVSSPSSPPNNSPFPFAYPNPMMFMPPP
PLSAPQQQQQQQQQQQQEDQQQQQQQENPYIYYPTPNPIPVKMPKDEKTFKKRNNKNH
PANNSNNANKQANPYLENSIPTKNTSKKNASSKSNESTANNHKSHSHSHPHSQSLQQQ
QQTYHRSPLLEQLRNSSSDKNSNSNMSLKDIFGHSLEFCKDQHGSRFIQRELATSPAS
EKEVIFNEIRDDAIELSNDVFGNYVIQKFFEFGSKIQKNTLVDQFKGNMKQLSLQMYA
CRVIQKALEYIDSNQRIELVLELSDSVLQMIKDQNGNHVIQKAIETIPIEKLPFILSS
LTGHIYHLSTHSYGCRVIQRLLEFGSSEDQESILNELKDFIPYLIQDQYGNYVIQYVL
QQDQFTNKEMVDIKQEIIETVANNVVEYSKHKFASNVVEKSILYGSKNQKDLIISKIL
PRDKNHALNLEDDSPMILMIKDQFANYVIQKLVNVSEGEGKKLIVIAIRAYLDKLNKS
NSLGNRHLASVEKLAALVENAEV"
gene 125534..127255
/gene="YEH1"
/locus_tag="YLL012W"
/db_xref="GeneID:850648"
mRNA 125534..127255
/gene="YEH1"
/locus_tag="YLL012W"
/product="Yeh1p"
/transcript_id="NM_001181832.1"
/db_xref="GI:296146526"
/db_xref="GeneID:850648"
CDS 125534..127255
/gene="YEH1"
/locus_tag="YLL012W"
/EC_number="3.1.1.13"
/note="Steryl ester hydrolase, one of three gene products
(Yeh1p, Yeh2p, Tgl1p) responsible for steryl ester
hydrolase activity and involved in sterol homeostasis;
localized to lipid particle membranes"
/codon_start=1
/product="Yeh1p"
/protein_id="NP_013089.1"
/db_xref="GI:6323017"
/db_xref="SGD:S000003935"
/db_xref="GeneID:850648"
/translation="MGVSAVLKRARNLLATFIVCCFMAVVLVLALAHHFINEHRDTRS
SSTQIEVDDESKRNVHHDHVLTRTNAYATPYLDLEHDKKNGIVYDHTRTVVRKKNHEV
GSSSLHKNLFHKFLTKLIFRFIEKEKVTEGVTQGKFNNSSNEIANHEPVFEKIPVQCD
NPLQNLILSEDLTLVADLNYYFNQYNIQIEEFRLETEDGFVIDLWHLIPKYRTTDSDK
KKRPPILMLHGLLQSSGSFASNGRKSLAYFLYQSGYDIWLGNNRCGFRPEWNEAKVPT
LASRWDWDLREMVKYDLTLLIDTVLAKTQFEKLTLISHSQGTTQGFMGLVNEDKFFPP
GSGSKESFFTSKIANYIALAPAVYPGPLLNEKLFVKLMTKEIENPWFFGETSFFEIMM
IVRNLCVGESLFSFVCYTIFNYLFDWNDTLWDTALRDRHFLFSPVHVSVKLMQWWLSP
DPNKVSFKFGSHKMFPDNVKWFSDASKAPNIYLFVPKQDRLVDGERLINHFVNVESNV
NYKIWYIDEYAHIDVLWAHDVIERIGKPILQNLNNYYSKKPSSAFESDCSDTEVETEL
EMVAEKA"
gene 127523..128992
/gene="SOF1"
/locus_tag="YLL011W"
/db_xref="GeneID:850649"
mRNA 127523..128992
/gene="SOF1"
/locus_tag="YLL011W"
/product="Sof1p"
/transcript_id="NM_001181831.1"
/db_xref="GI:296146527"
/db_xref="GeneID:850649"
CDS 127523..128992
/gene="SOF1"
/locus_tag="YLL011W"
/note="Essential protein required for biogenesis of 40S
(small) ribosomal subunit; has similarity to the beta
subunit of trimeric G-proteins and the splicing factor
Prp4p"
/codon_start=1
/product="Sof1p"
/protein_id="NP_013090.1"
/db_xref="GI:6323018"
/db_xref="SGD:S000003934"
/db_xref="GeneID:850649"
/translation="MKIKTIKRSADDYVPVKSTQESQMPRNLNPELHPFERAREYTKA
LNATKLERMFAKPFVGQLGYGHRDGVYAIAKNYGSLNKLATGSADGVIKYWNMSTREE
FVSFKAHYGLVTGLCVTQPRFHDKKPDLKSQNFMLSCSDDKTVKLWSINVDDYSNKNS
SDNDSVTNEEGLIRTFDGESAFQGIDSHRENSTFATGGAKIHLWDVNRLKPVSDLSWG
ADNITSLKFNQNETDILASTGSDNSIVLYDLRTNSPTQKIVQTMRTNAICWNPMEAFN
FVTANEDHNAYYYDMRNLSRSLNVFKDHVSAVMDVDFSPTGDEIVTGSYDKSIRIYKT
NHGHSREIYHTKRMQHVFQVKYSMDSKYIISGSDDGNVRLWRSKAWERSNVKTTREKN
KLEYDEKLKERFRHMPEIKRISRHRHVPQVIKKAQEIKNIELSSIKRREANERRTRKD
MPYISERKKQIVGTVHKYEDSGRDRKRRKEDDKRDTQEK"
gene complement(129330..130613)
/gene="PSR1"
/locus_tag="YLL010C"
/db_xref="GeneID:850650"
mRNA complement(129330..130613)
/gene="PSR1"
/locus_tag="YLL010C"
/product="Psr1p"
/transcript_id="NM_001181830.1"
/db_xref="GI:296146528"
/db_xref="GeneID:850650"
CDS complement(129330..130613)
/gene="PSR1"
/locus_tag="YLL010C"
/EC_number="3.1.3.-"
/note="Plasma membrane associated protein phosphatase
involved in the general stress response; required along
with binding partner Whi2p for full activation of
STRE-mediated gene expression, possibly through
dephosphorylation of Msn2p"
/codon_start=1
/product="Psr1p"
/protein_id="NP_013091.1"
/db_xref="GI:6323019"
/db_xref="SGD:S000003933"
/db_xref="GeneID:850650"
/translation="MGFISSILCCSSETTQSNSNSAYRQQQSSSLNKNRSVKHSNTKS
RTRGVHQTNSPPSKTNSAATFSSTERSTGKSGISTNDNEKKKPSSPTAAVTATTTNNM
TKVEKRISKDDLYEEKYEVDEDEEIDDEDNRRSRGIVQEKGDAVKDTSRQKKQQQQQQ
QQSQPQPQPQSQSQSQSQSQSQQRGPTVQVSSDHLIQDMNLSRVSSSSQASETSNDAD
DEDDEDEEYIDLTLLQQGQYHAPGYNTLLPPQDESTKGKKCLILDLDETLVHSSFKYL
RSADFVLSVEIDDQVHNVYVIKRPGVEEFLERVGKLFEVVVFTASVSRYGDPLLDILD
TDKVIHHRLFREACYNYEGNYIKNLSQIGRPLSDIIILDNSPASYIFHPQHAIPISSW
FSDTHDNELLDIIPLLEDLSVKTSLDVGKILDVTI"
gene complement(131205..131414)
/gene="COX17"
/locus_tag="YLL009C"
/db_xref="GeneID:850651"
mRNA complement(131205..131414)
/gene="COX17"
/locus_tag="YLL009C"
/product="Cox17p"
/transcript_id="NM_001181829.1"
/db_xref="GI:296146529"
/db_xref="GeneID:850651"
CDS complement(131205..131414)
/gene="COX17"
/locus_tag="YLL009C"
/note="Copper metallochaperone that transfers copper to
Sco1p and Cox11p for eventual delivery to cytochrome c
oxidase; contains twin cysteine-x9-cysteine motifs"
/codon_start=1
/product="Cox17p"
/protein_id="NP_013092.1"
/db_xref="GI:6323020"
/db_xref="SGD:S000003932"
/db_xref="GeneID:850651"
/translation="MTETDKKQEQENHAECEDKPKPCCVCKPEKEERDTCILFNGQDS
EKCKEFIEKYKECMKGYGFEVPSAN"
gene 131729..133987
/gene="DRS1"
/locus_tag="YLL008W"
/db_xref="GeneID:850652"
mRNA 131729..133987
/gene="DRS1"
/locus_tag="YLL008W"
/product="Drs1p"
/transcript_id="NM_001181828.1"
/db_xref="GI:296146530"
/db_xref="GeneID:850652"
CDS 131729..133987
/gene="DRS1"
/locus_tag="YLL008W"
/EC_number="3.6.1.-"
/note="Nucleolar DEAD-box protein required for ribosome
assembly and function, including synthesis of 60S
ribosomal subunits; constituent of 66S pre-ribosomal
particles"
/codon_start=1
/product="Drs1p"
/protein_id="NP_013093.1"
/db_xref="GI:6323021"
/db_xref="SGD:S000003931"
/db_xref="GeneID:850652"
/translation="MVVGTKKYSNLDFVPTISDSEDDVPILDSSDDEKVEAKKTTKKR
KGKNNKKKVSEGDNLDEDVHEDLDAGFKFDLDADDTTSNFQGWNFLAEGESNKDDAEA
FVKKDVDLDKIIRRKGGLVKMAHIDSKQEEETEKEKVEKENDSDDEELAMDGFGMGAP
MNNGDENQSEEEEEEEEKEEEEEEEEEQEEMTLEKGGKDDEIDEEDDSEEAKADFYAP
ETEGDEAKKQMYENFNSLSLSRPVLKGLASLGYVKPSPIQSATIPIALLGKDIIAGAV
TGSGKTAAFMIPIIERLLYKPAKIASTRVIVLLPTRELAIQVADVGKQIARFVSGITF
GLAVGGLNLRQQEQMLKSRPDIVIATPGRFIDHIRNSASFNVDSVEILVMDEADRMLE
EGFQDELNEIMGLLPSNRQNLLFSATMNSKIKSLVSLSLKKPVRIMIDPPKKAATKLT
QEFVRIRKRDHLKPALLFNLIRKLDPTGQKRIVVFVARKETAHRLRIIMGLLGMSVGE
LHGSLTQEQRLDSVNKFKNLEVPVLICTDLASRGLDIPKIEVVINYDMPKSYEIYLHR
VGRTARAGREGRSVTFVGESSQDRSIVRAAIKSVEENKSLTQGKALGRNVDWVQIEET
NKLVESMNDTIEDILVEEKEEKEILRAEMQLRKGENMLKHKKEIQARPRRTWFQSESD
KKNSKVLGALSRNKKVTNSKKRKREEAKADGNGARSYRKTKTDRIADQERTFKKQKST
NSNKKKGFKSRR"
gene complement(134302..136299)
/locus_tag="YLL007C"
/db_xref="GeneID:850653"
mRNA complement(134302..136299)
/locus_tag="YLL007C"
/product="hypothetical protein"
/transcript_id="NM_001181827.1"
/db_xref="GI:296146531"
/db_xref="GeneID:850653"
CDS complement(134302..136299)
/locus_tag="YLL007C"
/note="hypothetical protein; green fluorescent protein
(GFP)-fusion protein localizes to the cytoplasm; YLL007C
is not an essential gene"
/codon_start=1
/product="hypothetical protein"
/protein_id="NP_013094.1"
/db_xref="GI:6323022"
/db_xref="SGD:S000003930"
/db_xref="GeneID:850653"
/translation="MKHNRQMPDESLENIKVLLNPKLGKPVKSLTSAQSKACYHTLIS
NKNLNKTSDEYEKLLANYILLCDEKYLCKTVIPDSRFWAILCDNCQKLRSETLVANLI
RIFNVALKCQDSNKNEVIVSICHISRENSQLIGILLQLLSQRPIHIPLFTDTILCITL
FLKCSLTLCETSLSHAVEFVPRILILLFQYNFPASMSELLYIEDLQPLILEEFVPLKQ
RLINFLSSVSIDDYSCSLKADLLTAIKDNSVFQKGLEMEMGDLPSINLLNAYDTFTFL
NSPNGSFKRLYTEQLLFGENDFPLYEAIFKLSDQFRRLFNLSGKKENQYSDSERDLKL
QIATAVLNRQTCFYKTLELFLRFWIESLAKSQSDLVSLLNLAIITLKYVCLSSSDLEA
AIQTKSLLKTQVVALDSMRYKFARTLQLDSIKKEQYRTWSSSIASFDTMLSGQVRDYV
RHQRLLQLQKGTWVYAENPLNPEAGTPKVYFLIVSDNHANLLAREFETQTNDLPYLFD
NKILTSPGSEALANGRTKVVVLKHITSFKSIELTTPSRRTSSNVYIKLDEANVYTGVE
LKDRNDRTVLKFYLDTEEGRYIWLDGLKLISPFQHEDISEDTKEQIDTLFDLRKNVQM
INLNVRQDIIVPPPEPSDEDEDEEFYNLETLKKVTQNFYFD"
gene 136345..136521
/locus_tag="YLL006W-A"
/db_xref="GeneID:1466403"
mRNA 136345..136521
/locus_tag="YLL006W-A"
/product="hypothetical protein"
/transcript_id="NM_001184559.1"
/db_xref="GI:296146532"
/db_xref="GeneID:1466403"
CDS 136345..136521
/locus_tag="YLL006W-A"
/note="hypothetical protein; identified by fungal homology
and RT-PCR"
/codon_start=1
/product="hypothetical protein"
/protein_id="NP_878116.1"
/db_xref="GI:33438828"
/db_xref="SGD:S000028560"
/db_xref="GeneID:1466403"
/translation="MTQLSQSNVERVALVYISVYFFSCISLIVYFFTFCLSVSIPKNR
QHPIKIIYNNKCPS"
gene 136586..137866
/gene="MMM1"
/locus_tag="YLL006W"
/gene_synonym="YME6"
/db_xref="GeneID:850654"
mRNA 136586..137866
/gene="MMM1"
/locus_tag="YLL006W"
/gene_synonym="YME6"
/product="Mmm1p"
/transcript_id="NM_001181826.1"
/db_xref="GI:296146533"
/db_xref="GeneID:850654"
CDS 136586..137866
/gene="MMM1"
/locus_tag="YLL006W"
/gene_synonym="YME6"
/note="ER integral membrane protein, component of the
ERMES complex that links the ER to mitochondria and may
promote inter-organellar calcium and phospholipid exchange
as well as coordinating mitochondrial DNA replication and
growth"
/codon_start=1
/product="Mmm1p"
/protein_id="NP_013095.1"
/db_xref="GI:6323023"
/db_xref="SGD:S000003929"
/db_xref="GeneID:850654"
/translation="MTDSENESTETDSLMTFDDYISKELPEHLQRLIMENLKGSTTND
LKQTSNNSEFNVSKNGSFKGLDDAIQALQMQSVLHPSSLGSLATSSKFSGWSFAQGFF
VGQLSIVLLFIFFLKFFIFSDEPSKSKNPKPAASRHRSKFKEYPFISREFLTSLVRKG
AKQHYELNEEAENEHLQELALILEKTYYNVDVHPAESLDWFNVLVAQIIQQFRSEAWH
RDNILHSLNDFIGRKSPDLPEYLDTIKITELDTGDDFPIFSNCRIQYSPNSGNKKLEA
KIDIDLNDHLTLGVETKLLLNYPKPGIAALPINLVVSIVRFQACLTVSLTNAEEFAST
SNGSSSENGMEGNSGYFLMFSFSPEYRMEFEIKSLIGSRSKLENIPKIGSVIEYQIKK
WFVERCVEPRFQFVRLPSMWPRSKNTREEKPTEL"
gene complement(137940..140546)
/gene="SPO75"
/locus_tag="YLL005C"
/db_xref="GeneID:850655"
mRNA complement(137940..140546)
/gene="SPO75"
/locus_tag="YLL005C"
/product="Spo75p"
/transcript_id="NM_001181825.1"
/db_xref="GI:296146534"
/db_xref="GeneID:850655"
CDS complement(137940..140546)
/gene="SPO75"
/locus_tag="YLL005C"
/note="Meiosis-specific hypothetical protein, required for
spore wall formation during sporulation; dispensable for
both nuclear divisions during meiosis"
/codon_start=1
/product="Spo75p"
/protein_id="NP_013096.1"
/db_xref="GI:6323024"
/db_xref="SGD:S000003928"
/db_xref="GeneID:850655"
/translation="MNATKELTFNLLNKFQDKERFGSAQRHAGISLKGFISGILFSFL
YFLFQLSLFIILRSRFKTIYQANVVLKIHPGSKVCFAKKKIKNYWSLFAFLKQLPGRM
LDPMEKFERNERYGLDNYLFLRFLKLLIFFFAVLSIINIPILIPIHYFSRDILKENEG
ERYEQSFRTTSKLDKWTMSNLSPNSSNTLICHLFLSIFVVLWFHFILSSELRFVNRLG
YSVLTKSKYQNILYLEGFSSKLVTQSISLETFFQPLHSDCFGVTHFIPKNLKKVHKLE
IKLNKLQKSKEQIIFEIILEKYFRRVSIHRHLIANHKRFFFSKLKNHLLFQYKKLVFL
TQFRISYYCTKIRLRWKKSSIFPLYYPKLYVNTETILERKYRILDKIIRKEKLIKFQV
NSLKATSETKQALPDDLSSGTDIYMDKMFITFKSTLLSNVIGELLSYRLPTQNLKVII
GPNVNDIIWRNILDSSPLWKSAKYFSANILRIFVIIGWILPVAFLGLISQIPNISSLI
PFTKIIHFQSPFIREVAKNLIPIVTLIIIIEIVPYFFRWLSYLRGLKTGAQIEADVQN
WYFVFVFIHLFVVVTISSGFSIIIERLLNNPVSIPALLANDLPKCANFFCSFVLIRGM
AYAGGNLLRIKELLFELFYYKWKRSTPHAQFKRLKTSLFFQLGSIYPIFSVLGCIGII
YSVVAPIILLLCCISFSMVFFSFSYLFKYQYNKENYSETFGKLYIQALMQLYAGIYFM
EFCLLGLFTLFDQYTLSTIMLVVFALTVITHSKISKQIKSKPQRIPTLEYLSNLTEER
KDQFCQESYTFHDIFSICRNSDEIWLPRDKLGISEEEQSFLEKSYHLKFDLNMYSMNL
FGDCHLENSHLH"
rep_origin 138185..139164
/note="ARS1207;
Putative replication origin, identified in multiple array
studies, not yet confirmed by plasmid-based assay"
/db_xref="SGD:S000130181"
gene 141073..142923
/gene="ORC3"
/locus_tag="YLL004W"
/db_xref="GeneID:850656"
mRNA 141073..142923
/gene="ORC3"
/locus_tag="YLL004W"
/product="origin recognition complex subunit 3"
/transcript_id="NM_001181824.1"
/db_xref="GI:296146535"
/db_xref="GeneID:850656"
CDS 141073..142923
/gene="ORC3"
/locus_tag="YLL004W"
/note="Subunit of the origin recognition complex, which
directs DNA replication by binding to replication origins
and is also involved in transcriptional silencing"
/codon_start=1
/product="origin recognition complex subunit 3"
/protein_id="NP_013097.1"
/db_xref="GI:6323025"
/db_xref="SGD:S000003927"
/db_xref="GeneID:850656"
/translation="MSDLNQSKKMNVSEFADAQRSHYTVYPSLPQSNKNDKHIPFVKL
LSGKESEVNVEKRWELYHQLHSHFHDQVDHIIDNIEADLKAEISDLLYSETTQKRRCF
NTIFLLGSDSTTKIELKDESSRYNVLIELTPKESPNVRMMLRRSMYKLYSAADAEEHP
TIKYEDINDEDGDFTEQNNDVSYDLSLVENFKRLFGKDLAMVFNFKDVDSINFNTLDN
FIILLKSAFKYDHVKISLIFNINTNLSNIEKNLRQSTIRLLKRNYHKLDVSSNKGFKY
GNQIFQSFLDTVDGKLNLSDRFVEFILSKMANNTNHNLQLLTKMLDYSLMSYFFQNAF
SVFIDPVNVDFLNDDYLKILSRCPTFMFFVEGLIKQHAPADEILSLLTNKNRGLEEFF
VEFLVRENPINGHAKFVARFLEEELNITNFNLIELYHNLLIGKLDSYLDRWSACKEYK
DRLHFEPIDTIFQELFTLDNRSGLLTQSIFPSYKSNIEDNLLSWEQVLPSLDKENYDT
LSGDLDKIMAPVLGQLFKLYREANMTINIYDFYIAFRETLPKEEILNFIRKDPSNTKL
LELAETPDAFDKVALILFMQAIFAFENMGLIKFQSTKSYDLVEKCVWRGI"
gene 143201..146041
/gene="SFI1"
/locus_tag="YLL003W"
/db_xref="GeneID:850657"
mRNA 143201..146041
/gene="SFI1"
/locus_tag="YLL003W"
/product="Sfi1p"
/transcript_id="NM_001181823.1"
/db_xref="GI:296146536"
/db_xref="GeneID:850657"
CDS 143201..146041
/gene="SFI1"
/locus_tag="YLL003W"
/note="Centrin (Cdc31p)-binding protein required for
spindle pole body (SPB) duplication, localizes to the
half-bridge of the SPB, required for progression through
G(2)-M transition, has similarity to Xenopus laevis
XCAP-C"
/codon_start=1
/product="Sfi1p"
/protein_id="NP_013098.1"
/db_xref="GI:6323026"
/db_xref="SGD:S000003926"
/db_xref="GeneID:850657"
/translation="MGKFGTTNKSTENLLRDKFVPETSPTNIPTDVLIKQGQITDSTE
SLIHGGAERYIVNALKPIELNKTEGFFEDPPFHLPSPPVDSTNLEYEDVTDLPKNGLR
YDLNDISVEVIEDLYRQIEAFLVHFKLSRSFLQIFKNYVNILIQEGINPLRDEYFTIL
EDELKGFFTFNSVIEEILEIFLIHPRNKFIALSLAEYTYAKNKIRRHFNHWKTVCELN
EEANRFANQAKLRVQEAVFYIWSDKTLKYSQMANDEAESFRNTWLLFRSFQQWITLTQ
TLKEQSRLADQAFLNKMFRKILKAQEHWKHLETVNTDNIKKIFLRTTFHIWKLRHKEI
NYHGLERRIFERIKQKVINYEYNKSIAEKVRSFSLQRKYLNKWEKKNIENEDKLGALY
ELENKFIKQKFFRKLNRSFQHSQQEAIAKSKLNQTLLRCVFEKMWLKRFEDHLHLYSI
VSLKEANLVKRIFHSWKKLLYIDLKASDYSRTNLLKSSLRSWKLEVKLKIFEQKCKKS
IQASAYRTWRKRIQYGKISSEHVKTAFCAKYLGVWKRRMLQMNSMNDEASKFYEEGLV
NECLAIWKERLIKTKELEDRYNFLCKTHAILTVKRTLMHIDNVHLLYTKLAPSMDRVK
LSKAFLKWRKATRFKVRHKLNDILHVYEKSKERELQSQLFNAWRNRFCFYTEECNIQA
ISKRNYQLEKMVLKKFRERLLEIVKSEELADEVREEFVLVKTFYIWKTHLDEIFYMST
LLEQSEANKQFIITSKFLKMWSLRFLKIKRNDETVEVFRHRWDRATVRGLLLLWKNRS
DSSPKRRKDFNLKHELKTPIRSDSQNASTIPGSERIKQHRMEAMKSHYSRARRAIPSP
VKSSSVLDSTAKKQINLESTTGLNGSPTRGKPLRYSPRRTTRNMPSKVDHIDFGRIPA
VPFSLSANSPKIDQDMDYIREHDKSPLSRKRQ"
gene 146291..147601
/gene="RTT109"
/locus_tag="YLL002W"
/gene_synonym="KIM2; REM50"
/db_xref="GeneID:850658"
mRNA 146291..147601
/gene="RTT109"
/locus_tag="YLL002W"
/gene_synonym="KIM2; REM50"
/product="Rtt109p"
/transcript_id="NM_001181822.1"
/db_xref="GI:296146537"
/db_xref="GeneID:850658"
CDS 146291..147601
/gene="RTT109"
/locus_tag="YLL002W"
/gene_synonym="KIM2; REM50"
/note="Histone acetyltransferase critical for cell
survival in the presence of DNA damage during S phase;
acetylates H3-K56 and H3-K9; involved in non-homologous
end joining and in regulation of Ty1 transposition;
interacts physically with Vps75p"
/codon_start=1
/product="Rtt109p"
/protein_id="NP_013099.1"
/db_xref="GI:6323027"
/db_xref="SGD:S000003925"
/db_xref="GeneID:850658"
/translation="MSLNDFLSSVLPVSEQFEYLSLQSIPLETHAVVTPNKDDKRVPK
STIKTQHFFSLFHQGKVFFSLEVYVYVTLWDEADAERLIFVSKADTNGYCNTRVSVRD
ITKIILEFILSIDPNYYLQKVKPAIRSYKKISPELISAASTPARTLRILARRLKQSGS
TVLKEIESPRFQQDLYLSFTCPREILTKICLFTRPASQYLFPDSSKNSKKHILNGEEL
MKWWGFILDRLLIECFQNDTQAKLRIPGEDPARVRSYLRGMKYPLWQVGDIFTSKENS
LAVYNIPLFPDDPKARFIHQLAEEDRLLKVSLSSFWIELQERQEFKLSVTSSVMGISG
YSLATPSLFPSSADVIVPKSRKQFRAIKKYITGEEYDTEEGAIEAFTNIRDFLLLRMA
TNLQSLTGKREHRERNQPVPASNINTLAITMLKPRKKAKALPKT"
gene 147890..150163
/gene="DNM1"
/locus_tag="YLL001W"
/db_xref="GeneID:850686"
mRNA 147890..150163
/gene="DNM1"
/locus_tag="YLL001W"
/product="Dnm1p"
/transcript_id="NM_001181821.1"
/db_xref="GI:296146538"
/db_xref="GeneID:850686"
CDS 147890..150163
/gene="DNM1"
/locus_tag="YLL001W"
/EC_number="3.6.5.5"
/note="Dynamin-related GTPase required for mitochondrial
fission and morphology; assembles on the cytoplasmic face
of mitochondrial tubules at sites at which division will
occur; also participates in endocytosis and regulating
peroxisome abundance"
/codon_start=1
/product="Dnm1p"
/protein_id="NP_013100.1"
/db_xref="GI:6323028"
/db_xref="SGD:S000003924"
/db_xref="GeneID:850686"
/translation="MASLEDLIPTVNKLQDVMYDSGIDTLDLPILAVVGSQSSGKSSI
LETLVGRDFLPRGTGIVTRRPLVLQLNNISPNSPLIEEDDNSVNPHDEVTKISGFEAG
TKPLEYRGKERNHADEWGEFLHIPGKRFYDFDDIKREIENETARIAGKDKGISKIPIN
LKVFSPHVLNLTLVDLPGITKVPIGEQPPDIEKQIKNLILDYIATPNCLILAVSPANV
DLVNSESLKLAREVDPQGKRTIGVITKLDLMDSGTNALDILSGKMYPLKLGFVGVVNR
SQQDIQLNKTVEESLDKEEDYFRKHPVYRTISTKCGTRYLAKLLNQTLLSHIRDKLPD
IKTKLNTLISQTEQELARYGGVGATTNESRASLVLQLMNKFSTNFISSIDGTSSDINT
KELCGGARIYYIYNNVFGNSLKSIDPTSNLSVLDVRTAIRNSTGPRPTLFVPELAFDL
LVKPQIKLLLEPSQRCVELVYEELMKICHKCGSAELARYPKLKSMLIEVISELLRERL
QPTRSYVESLIDIHRAYINTNHPNFLSATEAMDDIMKTRRKRNQELLKSKLSQQENGQ
TNGINGTSSISSNIDQDSAKNSDYDDDGIDAESKQTKDKFLNYFFGKDKKGQPVFDAS
DKKRSIAGDGNIEDFRNLQISDFSLGDIDDLENAEPPLTEREELECELIKRLIVSYFD
IIREMIEDQVPKAVMCLLVNYCKDSVQNRLVTKLYKETLFEELLVEDQTLAQDRELCV
KSLGVYKKAATLISNIL"
centromere complement(150828..150947)
/note="CEN12; Chromosome XII centromere"
/db_xref="SGD:S000006473"
centromere complement(150828..150852)
/note="CEN12_CDEIII of CEN12"
centromere complement(150853..150937)
/note="CEN12_CDEII of CEN12"
centromere complement(150938..150947)
/note="CEN12_CDEI of CEN12"
rep_origin 150947..151389
/note="ARS1208;
Autonomously Replicating Sequence"
/db_xref="SGD:S000114848"
gene complement(151389..153977)
/locus_tag="YLR001C"
/db_xref="GeneID:850687"
mRNA complement(151389..153977)
/locus_tag="YLR001C"
/product="hypothetical protein"
/transcript_id="NM_001181888.1"
/db_xref="GI:296146539"
/db_xref="GeneID:850687"
CDS complement(151389..153977)
/locus_tag="YLR001C"
/note="hypothetical protein; the authentic, non-tagged
protein is detected in highly purified mitochondria in
high-throughput studies; predicted to be palmitoylated"
/codon_start=1
/product="hypothetical protein"
/protein_id="NP_013101.1"
/db_xref="GI:6323029"
/db_xref="SGD:S000003991"
/db_xref="GeneID:850687"
/translation="MNMAIQTIKYIFWLLPILGLTQALLQNPGDDFPFSTVIDILSEN
VEFSTFLRIIQKTGHVQYLNELQNFTLFAPINSAFIKGDQTTDQFEEHFHIEDFLIHD
RVLQVRDLENGTYLEKRAAKAPLLLRKHERHCFVNEIAVVEPDLLPSFQNASLQGINN
LLLIQPQINELLVQLDEETQDLKIFSDFISSFSNYNAYTNSSTVLVPLDVNFRKFFNT
IEINYLLDKYNKLGKSNTISQAKWAADRTSLLQELIIDDVYGGILPKELILENKNNRK
LFMKSNSEGTSVSVNNSDYSPISNRIFEIGVVHGFSDLDFLRTHIQFDAEKYLHGLNC
SEFVKELYFRDLEKFIQNGRKITIFVPQASFNEDRGYTKPSLLYHFVEGKIDLEQDFS
SLRPIQYAPTQIYDSAFCSSAKRLGGHCQKFKITRSNKGYYINGRFKILNTKPYEIGN
TSIYSIDDDLQLPGDLVLSLAPENHCSISLMLLKELNLLDLPSNHKGYTILLPCMNSW
DNNDLTIDYLRSNKTALNLLMRNLIFEDLIYSNNYSISTTVKNLYGNSVSIGVQKIVG
SQNLTKISVSTIKESIIIEESSDIFFNQGVIHPIDQLDFPVDLEISLKELIETTGTKE
IFDFFNLFYDLSSIIWNNEEYSLLVPTASSIPLSGITANSTNLRKFLELHLIPANVTQ
NLLDCNGSISTKLGTKLNCRKDHLDNVFVSIQGDWTKEVRVLKTGCTTNLKSSCIFLI
DKPISLSWLNSEKYHLRLPGIAVGFGVIIGVTIAISLLFCIIITRGGKVKDKNQRGRN
DRATTPLIQHSPIIHNPSYSATAHLSPLSQPTFEGSYSVNAIQTPRDIRRVGSDQKGG
RSVSTS"
gene complement(154343..156334)
/gene="NOC3"
/locus_tag="YLR002C"
/db_xref="GeneID:850688"
mRNA complement(154343..156334)
/gene="NOC3"
/locus_tag="YLR002C"
/product="Noc3p"
/transcript_id="NM_001181889.1"
/db_xref="GI:296146540"
/db_xref="GeneID:850688"
CDS complement(154343..156334)
/gene="NOC3"
/locus_tag="YLR002C"
/note="Protein that forms a nuclear complex with Noc2p
that binds to 66S ribosomal precursors to mediate their
intranuclear transport; also binds to chromatin to promote
the association of DNA replication factors and replication
initiation"
/codon_start=1
/product="Noc3p"
/protein_id="NP_013102.1"
/db_xref="GI:6323030"
/db_xref="SGD:S000003992"
/db_xref="GeneID:850688"
/translation="MAKRNRSQFRIQERTAKKRKHEDSLLEGNVFQNAPEDMDENTIY
SAKGSSWDEEEQDYEMVPRKNRSDTSNLVEGLPIKVNGKVERKLHKAQEKPKDDDEED
EDSNDSSEDDEGPNEEQEAEAKEDEPDTEEKILQLKEDIADLVTKVMEEPEENTAALG
RLCKMVESKNPNTCKFSMLALVPVFKSIIPGYRIRPLTETEKKEKVSKEVSKLRNFEQ
ALVYNYKNYVGRLQSLSKTPSNAAPIQVSLGILATQAAKELISTASHFNFRTDIFTLL
LRRICKPRISTDPTSIQIIQTFETLLNEDEEGSISFEILRIFNKILKTRNFNIEESVL
NMLLSLDVLHDYDPNTKLKGNVSAPKLKKKDRVHLSKKQRKARKEMQQIEEEMRNAEQ
AVSAEERERNQSEILKIVFTIYLNILKNNAKTLIGSVLEGLTKFGNMANFDLLGDFLE
VMKELISDTEFDNLSSAEVRKALLCIVSAFSLISNTQYMKVNVDLSKFVDGLYALLPY
ICLDADIELSYRSLRLADPLNNEIIKPSVNVSTKAELLLKALDHVFFRSKSGTKERAT
AFTKRLYMCISHTPEKTSIAILKFIDKLMNRYPEISGLYSSEDRIGNGHFIMEADNPS
RSNPEAATLWDNALLEKHYCPVVTKGLRSLSSRSKECSK"
rep_origin 156648..156884
/note="ARS1209;
Autonomously Replicating Sequence"
/db_xref="SGD:S000118470"
gene complement(156855..157730)
/gene="CMS1"
/locus_tag="YLR003C"
/db_xref="GeneID:850689"
mRNA complement(156855..157730)
/gene="CMS1"
/locus_tag="YLR003C"
/product="Cms1p"
/transcript_id="NM_001181890.1"
/db_xref="GI:296146541"
/db_xref="GeneID:850689"
CDS complement(156855..157730)
/gene="CMS1"
/locus_tag="YLR003C"
/note="Putative subunit of the 90S preribosome processome
complex; overexpression rescues supressor mutant of mcm10;
null mutant is viable; relocalizes from nucleus to
cytoplasm upon DNA replication stress"
/codon_start=1
/product="Cms1p"
/protein_id="NP_013103.1"
/db_xref="GI:6323031"
/db_xref="SGD:S000003993"
/db_xref="GeneID:850689"
/translation="MSNPDDLDDGLAYDFDAEHEVIFDAKDGSPPTKKVQKRSIEQDD
DDVDDIDGKKEERNSEDDSNRPISKRQKKLQKKSKLIEKKKEESQYIVSQRKALPASS
PEKIIEYLTTLIREKNPDLSVLELEELYFKRNDFLSTEKFDAERRLSNFPAFIQKFSV
APKKIVFSMSNIRVADVYRSLNGGKNCVKLFSKSKLKDDIATVERLLTDSSKKSNKNK
DSLYFIATPTRMQKIIEATDLLFQGKEKLDIILDASYLDPKDNTILSFENAAVLCQVL
KTFLNKKSSVKILLY"
gene complement(157934..159505)
/gene="THI73"
/locus_tag="YLR004C"
/db_xref="GeneID:850690"
mRNA complement(157934..159505)
/gene="THI73"
/locus_tag="YLR004C"
/product="Thi73p"
/transcript_id="NM_001181891.1"
/db_xref="GI:296146542"
/db_xref="GeneID:850690"
CDS complement(157934..159505)
/gene="THI73"
/locus_tag="YLR004C"
/note="Putative plasma membrane permease proposed to be
involved in carboxylic acid uptake and repressed by
thiamine; substrate of Dbf2p/Mob1p kinase; transcription
is altered if mitochondrial dysfunction occurs"
/codon_start=1
/product="Thi73p"
/protein_id="NP_013104.1"
/db_xref="GI:6323032"
/db_xref="SGD:S000003994"
/db_xref="GeneID:850690"
/translation="MKNMSQRSMDVEKKAANADSCSVSTSSINVDDADVALRFLKQNG
LDESSTANEDDVVAGEEANFYGSHELSPKVLRKVDLFILPFLCCTYLLMFLDKALLNY
AASMGIKDHLKGNEFSNLGTIFSAAYIFMEPVVTYLIQKFPISKILGTFITVWGIVLA
CHAACKTYASLMVVRTLLGLFESSSAVGCIAISGMYYTKSEQSARIGFWATQAGTGYI
VGGLISFGFLHYHGTAFTSWQIMFLVVGLVTVAFGVLTFLYLPDNVTNAWFLNKEEKI
QVVEHIRANQTGLETKKFKKQQVKELFLHDKFTWPMLLLTACSQISTGAIGTFSVTIT
GTFGFDKYETALLQLPIGAITAMIILITTQMLSRWGHITLITTSMYIPAIIGCIVLIS
LPLSHKIGNLFSLYLLYSGSCVITNIYIWNSCNTSGYTKRVFRNAITMIVYNVSCIIA
PQMFRAYSAPRYIPAKIALLVTQCVCVPLQLYIGYICKKENEKRDKEQEGQERKKYQF
LDLTDIENRNFRYIY"
gene 160049..161434
/gene="SSL1"
/locus_tag="YLR005W"
/db_xref="GeneID:850691"
mRNA 160049..161434
/gene="SSL1"
/locus_tag="YLR005W"
/product="Ssl1p"
/transcript_id="NM_001181892.1"
/db_xref="GI:296146543"
/db_xref="GeneID:850691"
CDS 160049..161434
/gene="SSL1"
/locus_tag="YLR005W"
/note="Component of the core form of RNA polymerase
transcription factor TFIIH, which has both protein kinase
and DNA-dependent ATPase/helicase activities and is
essential for transcription and nucleotide excision
repair; interacts with Tfb4p"
/codon_start=1
/product="Ssl1p"
/protein_id="NP_013105.1"
/db_xref="GI:6323033"
/db_xref="SGD:S000003995"
/db_xref="GeneID:850691"
/translation="MAPVVISESEEDEDRVAITRRTKRQVHFDGEGDDRVDQQQQQHS
SSHRDRDKHVQRKKKKRLSNRNLQGSNGGYAWEDEIKRSWDLVKVDDEGDMASLVASI
VEARKKRTAKKNITPYQRGIIRSLILTLDCSEAMLEKDLRPNRHAMIIQYAIDFVHEF
FDQNPISQMGIIIMRNGLAQLVSQVSGNPQDHIDALKSIRKQEPKGNPSLQNALEMAR
GLLLPVPAHCTREVLIVFGSLSTTDPGDIHQTIDSLVSEKIRVKVLGLSAQVAICKEL
CKATNYGDESFYKILLDETHLKELFNEAVTPLPVNKINKGFTLVKMGFPTRIFEDTPT
FCSCHSKLVYGGYFCPNCHSKVCSLPTVCPCCDLMLILSTHLARSYHHLMPLKTFAEV
PTTEKFRSEDCFSCQSRFPILKNHKNGKLLTSSRYRCEDCKQEFCVDCDVFIHEILHN
CPGCESKPVIT"
gene complement(161755..163893)
/gene="SSK1"
/locus_tag="YLR006C"
/db_xref="GeneID:850692"
mRNA complement(161755..163893)
/gene="SSK1"
/locus_tag="YLR006C"
/product="Ssk1p"
/transcript_id="NM_001181893.1"
/db_xref="GI:296146544"
/db_xref="GeneID:850692"
CDS complement(161755..163893)
/gene="SSK1"
/locus_tag="YLR006C"
/note="Cytoplasmic response regulator; part of a
two-component signal transducer that mediates osmosensing
via a phosphorelay mechanism; required for mitophagy;
dephosphorylated form is degraded by the
ubiquitin-proteasome system; potential Cdc28p substrate"
/codon_start=1
/product="Ssk1p"
/protein_id="NP_013106.1"
/db_xref="GI:6323034"
/db_xref="SGD:S000003996"
/db_xref="GeneID:850692"
/translation="MLNSALLWKVWLRIDNSTDEVNQPIAVQFDEIDTVDDLKSRFFQ
KLSSTRWREINDNASIAIGLYAPKFDNQADNTSSNNTNDNSCRSKSNGAGSGANLSVN
SNTKSSVSPTAGSFGLSKDLAKDRNVLQHPKPTQKRGALYDAFAAVPTVAATTNVDFP
PNEAPMLSPQRPYSTSPKQFPATTKSPLLRFASVSPYPKFHSDNQIMASAGLTYVSPH
NKNKYTRPLIRKGLNFTTESVNDCTYKIIFEPDELAINIYKELFGTMGSQPASQPLLI
FSNVNLRQDVPPLDILNVVDYVPTNEEISQQKTQPTDHGAVGVFHLDDHISPGEQGLK
QTIGDKADLKGKDGNSSPQEFKLITDEEQLRRASQELKDEEKDAESPWQAILLLPKGY
KGGVDFRNKPVAHTDSSFNNEDTITHSELEVNTGSPSQESGSLNEAGIGITQPMSEVQ
RRKEDVTPASPILTSSQTPHYSNSLYNAPFAVSSPPDPLPNLFTTTSEKVFPKINVLI
VEDNVINQAILGSFLRKHKISYKLAKNGQEAVNIWKEGGLHLIFMDLQLPVLSGIEAA
KQIRDFEKQNGIGIQKSLNNSHSNLEKGTSKRFSQAPVIIVALTASNSQMDKRKALLS
GCNDYLTKPVNLHWLSKKITEWGCMQALIDFDSWKQGESRMTDSVLVKSPQKPIAPSN
PHSFKQATSMTPTHSPVRKNSNLSPTQIEL"
gene 164392..165402
/gene="NSE1"
/locus_tag="YLR007W"
/db_xref="GeneID:850693"
mRNA 164392..165402
/gene="NSE1"
/locus_tag="YLR007W"
/product="Nse1p"
/transcript_id="NM_001181894.1"
/db_xref="GI:296146545"
/db_xref="GeneID:850693"
CDS 164392..165402
/gene="NSE1"
/locus_tag="YLR007W"
/note="Component of the SMC5-SMC6 complex; this complex
plays a key role in the removal of X-shaped DNA structures
that arise between sister chromatids during DNA
replication and repair"
/codon_start=1
/product="Nse1p"
/protein_id="NP_013107.1"
/db_xref="GI:6323035"
/db_xref="SGD:S000003997"
/db_xref="GeneID:850693"
/translation="MEVHEEQVSAPVTGDATAKYLLQYILSARGICHENALILALMRL
ETDASTLNTEWSIQQWVDKLNDYINAINVKLNLLGYKIIRINHGIGRNAVTLKAKQNF
ESFEDNTAIRAHNNDYAVLQSIVLPESNRFFVYVNLASTEETKLATRFNQNEIEFMKW
AIEQFMISGETIVEGPALETSIIVKEVNRILVAATGDSNLAKWRKFSTFTVGSTNLFQ
FQELTATDIEDLLLRLCELKWFYRTQEGKFGIDLRCIAELEEYLTSMYNLNTCQNCHK
LAIQGVRCGNESCREENEETGENSLSQIWHVDCFKHYITHVSKNCDRCGSSLITEGVY
VI"
gene complement(165577..166083)
/gene="PAM18"
/locus_tag="YLR008C"
/gene_synonym="TIM14"
/db_xref="GeneID:850694"
mRNA complement(165577..166083)
/gene="PAM18"
/locus_tag="YLR008C"
/gene_synonym="TIM14"
/product="Pam18p"
/transcript_id="NM_001181895.1"
/db_xref="GI:296146546"
/db_xref="GeneID:850694"
CDS complement(165577..166083)
/gene="PAM18"
/locus_tag="YLR008C"
/gene_synonym="TIM14"
/note="Constituent of the import motor (PAM complex)
component of the Translocase of the Inner Mitochondrial
membrane (TIM23 complex); essential J-protein cochaperone
that stimulates Ssc1p ATPase activity to drive import;
inhibited by Pam16p"
/codon_start=1
/product="Pam18p"
/protein_id="NP_013108.1"
/db_xref="GI:6323036"
/db_xref="SGD:S000003998"
/db_xref="GeneID:850694"
/translation="MSSQSNTGNSIEAPQLPIPGQTNGSANVTVDGAGVNVGIQNGSQ
GQKTGMDLYFDQALNYMGEHPVITGFGAFLTLYFTAGAYKSISKGLNGGKSTTAFLKG
GFDPKMNSKEALQILNLTENTLTKKKLKEVHRKIMLANHPDKGGSPFLATKINEAKDF
LEKRGISK"
gene 166537..167136
/gene="RLP24"
/locus_tag="YLR009W"
/db_xref="GeneID:850695"
mRNA 166537..167136
/gene="RLP24"
/locus_tag="YLR009W"
/product="Rlp24p"
/transcript_id="NM_001181896.1"
/db_xref="GI:296146547"
/db_xref="GeneID:850695"
CDS 166537..167136
/gene="RLP24"
/locus_tag="YLR009W"
/note="Essential protein with similarity to Rpl24Ap and
Rpl24Bp, associated with pre-60S ribosomal subunits and
required for ribosomal large subunit biogenesis"
/codon_start=1
/product="Rlp24p"
/protein_id="NP_013109.1"
/db_xref="GI:6323037"
/db_xref="SGD:S000003999"
/db_xref="GeneID:850695"
/translation="MRIYQCHFCSSPCYPGHGIMFVRNDAKEFRFCRSKCHKAFKQRR
NPRKLKWTKAFRKAAGKELAVDSTLTFAQRRNVPVRYNRELVATTLKAMARIEEIRQK
RERAFYKNRMRGNKEKDFLRDKKLVESNPELLRIREVEIARKLAKEQERAESVSEQEE
SEEEEEDMEIDSDEEEEEQLEKQKILLKNRRRNTKKIAF"
gene complement(167320..167802)
/gene="TEN1"
/locus_tag="YLR010C"
/db_xref="GeneID:850696"
mRNA complement(167320..167802)
/gene="TEN1"
/locus_tag="YLR010C"
/product="Ten1p"
/transcript_id="NM_001181897.1"
/db_xref="GI:296146548"
/db_xref="GeneID:850696"
CDS complement(167320..167802)
/gene="TEN1"
/locus_tag="YLR010C"
/note="Protein that regulates telomeric length; protects
telomeric ends in a complex with Cdc13p and Stn1p"
/codon_start=1
/product="Ten1p"
/protein_id="NP_013110.1"
/db_xref="GI:6323038"
/db_xref="SGD:S000004000"
/db_xref="GeneID:850696"
/translation="MSQLVLDLKCLKDKIATNYDIHNNVYGGNGMEPNIIHPSKRFRI
VVRLVDFLFCKSDEEFIKGFFCQMIVRNLHCLNSTNGAEEMRLYMSERLFSAHKDDLR
LINGQVLDVRIGVWYGIHQSPPIFEIIDFKILSRNDVRDFCEFVKSPLGEKFLNISNS
"
gene complement(167944..168025)
/locus_tag="tS(AGA)L"
/db_xref="GeneID:850697"
tRNA complement(167944..168025)
/locus_tag="tS(AGA)L"
/product="tRNA-Ser"
/note="Serine tRNA (tRNA-Ser), predicted by tRNAscan-SE
analysis"
/db_xref="SGD:S000006728"
/db_xref="GeneID:850697"
LTR complement(168043..168380)
/note="Ty3 LTR"
/db_xref="SGD:S000007079"
gene 169103..169678
/gene="LOT6"
/locus_tag="YLR011W"
/db_xref="GeneID:850698"
mRNA 169103..169678
/gene="LOT6"
/locus_tag="YLR011W"
/product="Lot6p"
/transcript_id="NM_001181898.1"
/db_xref="GI:296146549"
/db_xref="GeneID:850698"
CDS 169103..169678
/gene="LOT6"
/locus_tag="YLR011W"
/note="FMN-dependent NAD(P)H:quinone reductase, may be
involved in quinone detoxification; expression elevated at
low temperature; sequesters the Cin5p transcription factor
in the cytoplasm in complex with the proteasome under
reducing conditions"
/codon_start=1
/product="Lot6p"
/protein_id="NP_013111.1"
/db_xref="GI:6323039"
/db_xref="SGD:S000004001"
/db_xref="GeneID:850698"
/translation="MKVGIIMGSVRAKRVCPEIAAYVKRTIENSEELIDQKLKIQVVD
LQQIALPLYEDDDELIPAQIKSVDEYADSKTRSWSRIVNALDIIVFVTPQYNWGYPAA
LKNAIDRLYHEWHGKPALVVSYGGHGGSKCNDQLQEVLHGLKMNVIGGVAVKIPVGTI
PLPEDIVPQLSVHNEEILQLLASCIETTRNK"
gene complement(169982..170281)
/locus_tag="YLR012C"
/db_xref="GeneID:850699"
mRNA complement(169982..170281)
/locus_tag="YLR012C"
/product="hypothetical protein"
/transcript_id="NM_001181899.1"
/db_xref="GI:296146550"
/db_xref="GeneID:850699"
CDS complement(169982..170281)
/locus_tag="YLR012C"
/note="hypothetical protein; YLR012C is not an essential
gene"
/codon_start=1
/product="hypothetical protein"
/protein_id="NP_013112.2"
/db_xref="GI:37362676"
/db_xref="SGD:S000004002"
/db_xref="GeneID:850699"
/translation="MKTVYYKEITYQQYLQLQPEQQEKYLALCQKDFEQETERIAFDR
QGGVPGIARKFAQEEVAWFDRVTTWSYMNAYIPSYRRRRNLLKIDMLKMSNAEEY"
gene 171339..171764
/gene="GAT3"
/locus_tag="YLR013W"
/db_xref="GeneID:850700"
mRNA 171339..171764
/gene="GAT3"
/locus_tag="YLR013W"
/product="Gat3p"
/transcript_id="NM_001181900.1"
/db_xref="GI:296146551"
/db_xref="GeneID:850700"
CDS 171339..171764
/gene="GAT3"
/locus_tag="YLR013W"
/note="Protein containing GATA family zinc finger motifs"
/codon_start=1
/product="Gat3p"
/protein_id="NP_013113.1"
/db_xref="GI:6323041"
/db_xref="SGD:S000004003"
/db_xref="GeneID:850700"
/translation="MNIKTLCHPEYKRISVESLLNPVEETIDCEKPHSQTKINTAKPI
SASLYVTTNNTAVVQHNVQKRKGVTRRCPQCAVIKTSPQWREGPDGEVTLCNACGLFY
RKIFLVFGKDLAKRYFNEIKGVSVKRKVPKSLYGVTRTR"
gene complement(172268..174982)
/gene="PPR1"
/locus_tag="YLR014C"
/db_xref="GeneID:850701"
mRNA complement(172268..174982)
/gene="PPR1"
/locus_tag="YLR014C"
/product="Ppr1p"
/transcript_id="NM_001181901.1"
/db_xref="GI:296146552"
/db_xref="GeneID:850701"
CDS complement(172268..174982)
/gene="PPR1"
/locus_tag="YLR014C"
/note="Zinc finger transcription factor containing a
Zn(2)-Cys(6) binuclear cluster domain, positively
regulates transcription of URA1, URA3, URA4, and URA10,
which are involved in de novo pyrimidine biosynthesis, in
response to pyrimidine starvation; activity may be
modulated by interaction with Tup1p"
/codon_start=1
/product="Ppr1p"
/protein_id="NP_013114.1"
/db_xref="GI:6323042"
/db_xref="SGD:S000004004"
/db_xref="GeneID:850701"
/translation="MKQKKFNSKKSNRTDLSKRGDSPNIGISKSRTACKRCRLKKIKC
DQEFPSCKRCAKLEVPCVSLDPATGKDVPRSYVFFLEDRLAVMMRVLKEYGVDPTKIR
GNIPATSDDEPFDLKKYSSVSSLGEEGILPHNGLLADYLVQKGNSMASSAITSKSMAS
PQTINVQRKEFLVNSKKQDGSALLPETGSPMTSDARAEELRRCNKEISALGTMRESSF
NSFLGDSSGISFAKLVFTATNFRQDSGDDVLDEDIKQREQKYNGYAEAENNPHFDPLE
LPPRHAAEVMISRFFVDTNSQLPLLHRELFLKKYFEPIYGPWNPNIALASDQTGINSA
FEIPITSAFSAHTEPKRENVTEKIDVCSSVDVPWYDTWETSQKVNMRPIVELPTKFHI
PYFFLNIIFAIGHATQVLKSDITTVATYKRRATKYIASLFSSSDRLEALAGTLLMVIY
SIMRPNVPGVWYTMGSVLRLTVDLGLHSEKINKNYDAFTREIRRRLFWCVYSLDRQIC
SYFGRPFGIPEESITTRYPSLLDDSFITLTNREIDDYSDLPSPNPSSKVIALAMYKIR
RIQASIVRILYAPGAELPRRFMDLESWRIETYNELERWFQVDVPKNFEMMNCKFNSIW
FDLNYHYSKSILYGLSPKFPTLNDTAFKIVLDSTKGTIDVFYNLCVNKKIGYTWVAVH
NMFMTGMTYLYVNFYSKNNINDCQEKVSEYTEKVLIVLKNLIGFCESAKTCYTSYKIL
SSVVIKLKFMQINDAKGIFSDSNPLTSQANRMSSYDKKTNVLGFDDGTFDNKVFNRTN
FEEKAPFDIPLDEFFTELEKHSNVSQFNTLDVSEGNQVINESASTNTSSALNCQSYTN
NQDIMDILFQVTSGSVWDEFFVRSGNGNEGESSYDISKGKNSESGGIF"
gene 175227..176744
/gene="BRE2"
/locus_tag="YLR015W"
/gene_synonym="CPS60"
/db_xref="GeneID:850702"
mRNA 175227..176744
/gene="BRE2"
/locus_tag="YLR015W"
/gene_synonym="CPS60"
/product="Bre2p"
/transcript_id="NM_001181902.1"
/db_xref="GI:296146553"
/db_xref="GeneID:850702"
CDS 175227..176744
/gene="BRE2"
/locus_tag="YLR015W"
/gene_synonym="CPS60"
/note="Subunit of COMPASS (Set1C) complex, which
methylates Lys4 of histone H3 and functions in silencing
at telomeres; has a C-terminal Sdc1 Dpy-30 Interaction
(SDI) domain that mediates binding to Sdc1p; similar to
trithorax-group protein ASH2L"
/codon_start=1
/product="Bre2p"
/protein_id="NP_013115.1"
/db_xref="GI:6323043"
/db_xref="SGD:S000004005"
/db_xref="GeneID:850702"
/translation="MKLGIIPYQEGTDIVYKNALQGQQEGKRPNLPQMEATHQIKSSV
QGTSYEFVRTEDIPLNRRHFVYRPCSANPFFTILGYGCTEYPFDHSGMSVMDRSEGLS
ISRDGNDLVSVPDQYGWRTARSDVCIKEGMTYWEVEVIRGGNKKFADGVNNKENADDS
VDEVQSGIYEKMHKQVNDTPHLRFGVCRREASLEAPVGFDVYGYGIRDISLESIHEGK
LNCVLENGSPLKEGDKIGFLLSLPSIHTQIKQAKEFTKRRIFALNSHMDTMNEPWRED
AENGPSRKKLKQETTNKEFQRALLEDIEYNDVVRDQIAIRYKNQLFFEATDYVKTTKP
EYYSSDKRERQDYYQLEDSYLAIFQNGKYLGKAFENLKPLLPPFSELQYNEKFYLGYW
QHGEARDESNDKNTTSAKKKKQQQKKKKGLILRNKYVNNNKLGYYPTISCFNGGTARI
ISEEDKLEYLDQIRSAYCVDGNSKVNTLDTLYKEQIAEDIVWDIIDELEQIALQQ"
gene complement(176802..177416)
/gene="PML1"
/locus_tag="YLR016C"
/db_xref="GeneID:850703"
mRNA complement(176802..177416)
/gene="PML1"
/locus_tag="YLR016C"
/product="Pml1p"
/transcript_id="NM_001181903.1"
/db_xref="GI:296146554"
/db_xref="GeneID:850703"
CDS complement(176802..177416)
/gene="PML1"
/locus_tag="YLR016C"
/note="Subunit of the RES complex, which is required for
nuclear retention of unspliced pre-mRNAs; acts in the same
pathway as Pml39p and Mlp1p"
/codon_start=1
/product="Pml1p"
/protein_id="NP_013116.1"
/db_xref="GI:6323044"
/db_xref="SGD:S000004006"
/db_xref="GeneID:850703"
/translation="MFHRRKRPYNTRNYGHDDKKFKSQYIDIMPDFSPSGLLELESNN
KEGIALKHVEPQDAISPDNYMDMLGLEARDRTMYELVIYRKNDKDKGPWKRYDLNGRS
CYLVGRELGHSLDTDLDDRTEIVVADIGIPEETSSKQHCVIQFRNVRGILKCYVMDLD
SSNGTCLNNVVIPGARYIELRSGDVLTLSEFEEDNDYELIFMNV"
gene 177608..178621
/gene="MEU1"
/locus_tag="YLR017W"
/db_xref="GeneID:850704"
mRNA 177608..178621
/gene="MEU1"
/locus_tag="YLR017W"
/product="S-methyl-5-thioadenosine phosphorylase"
/transcript_id="NM_001181904.1"
/db_xref="GI:296146555"
/db_xref="GeneID:850704"
CDS 177608..178621
/gene="MEU1"
/locus_tag="YLR017W"
/note="Methylthioadenosine phosphorylase (MTAP), catalyzes
the initial step in the methionine salvage pathway;
affects polyamine biosynthesis through regulation of
ornithine decarboxylase (Spe1p) activity; regulates ADH2
gene expression"
/codon_start=1
/product="S-methyl-5-thioadenosine phosphorylase"
/protein_id="NP_013117.1"
/db_xref="GI:6323045"
/db_xref="SGD:S000004007"
/db_xref="GeneID:850704"
/translation="MNRIKNTFSVAKRLKLSKVMTNSELPSIFEGTVDLGIIGGTGLY
NLDCLEPIALLPPMVTPWGTTSSPVTISQFVGTNSHFHVAFIARHGINHEYPPTKVPF
RANMAALKNLNCKAVLSFSAVGSLQPHIKPRDFVLPQQIIDRTKGIRHSSYFNDEGLV
GHVGFGQPFSQKFAEYIYQFKNEITNPESEEPCHLHYDKDMTVVCMEGPQFSTRAESK
MYRMFGGHVINMSVIPEAKLARECELPYQMICMSTDYDAWRDEAEPVTVETVIGNLTN
NGRNANILASKIIVSMAKEIPEFMHTGDGLRGSIKKSISTKPEAMSKETLERLRYLFP
NYW"
gene complement(178707..179606)
/gene="POM34"
/locus_tag="YLR018C"
/db_xref="GeneID:850705"
mRNA complement(178707..179606)
/gene="POM34"
/locus_tag="YLR018C"
/product="Pom34p"
/transcript_id="NM_001181905.1"
/db_xref="GI:296146556"
/db_xref="GeneID:850705"
CDS complement(178707..179606)
/gene="POM34"
/locus_tag="YLR018C"
/note="Subunit of the transmembrane ring of the nuclear
pore complex (NPC); contributes to nucleocytoplasmic
transport, NPC biogenesis and spindle pole body
duplication"
/codon_start=1
/product="Pom34p"
/protein_id="NP_013118.1"
/db_xref="GI:6323046"
/db_xref="SGD:S000004008"
/db_xref="GeneID:850705"
/translation="MKIQAGQLGLDDNDVPGPLPDTDSKPSSQSQNDTPMFKLGNFES
PVLKELSRRTVNKEMETQRIMTNVIAFAFWNLLVKFIKFFWNNTHVGRQFCNRLSRIH
LYMLTFHTLKKANIIYHTTFSWLNAELLDYLFHLLISLNILFSLWKLLSTVKVSDLNL
TDRQKKLLGVDMQSSVDTGLQPQHPHYVSTSKISQMAQNKTHIPQTNLKNHPAYLFKG
LETPLKARQREMAEEQTKLQSQSLHTKNVFGTLQRHSGISSTLVSANNDNNSPHTPVT
RKGYIPSSKYAYMMNSQSPRGKI"
gene 180288..181481
/gene="PSR2"
/locus_tag="YLR019W"
/db_xref="GeneID:850706"
mRNA 180288..181481
/gene="PSR2"
/locus_tag="YLR019W"
/product="Psr2p"
/transcript_id="NM_001181906.1"
/db_xref="GI:296146557"
/db_xref="GeneID:850706"
CDS 180288..181481
/gene="PSR2"
/locus_tag="YLR019W"
/EC_number="3.1.3.-"
/note="Functionally redundant Psr1p homolog, a plasma
membrane phosphatase involved in the general stress
response; required with Psr1p and Whi2p for full
activation of STRE-mediated gene expression, possibly
through dephosphorylation of Msn2p"
/codon_start=1
/product="Psr2p"
/protein_id="NP_013119.1"
/db_xref="GI:6323047"
/db_xref="SGD:S000004009"
/db_xref="GeneID:850706"
/translation="MGFIANILCCSSDTSKTHRQRQPPETNHNRNRNRKHSSNKAQTQ
GRKQKATPNGDKMQYSTPEILLSSSDSGSNAGSKTMQENGNSGNGKLAPLSRDHSNNS
YDEEKEYEDYNEGDVEMTEVNNAGEEEEEDDEAKEKQDHVVHEYNVDADRNSSINDEA
PPQQGLYQVGQEDMNPQYVASSPDNDLNLIPTTEEDFSDLTHLQPDQYHAPGYDTLLP
PKLQEFQQKKCLILDLDETLVHSSFKYMHSADFVLPVEIDDQVHNVYVIKRPGVDEFL
NRVSQLYEVVVFTASVSRYANPLLDTLDPNGTIHHRLFREACYNYEGNYIKNLSQIGR
PLSETIILDNSPASYIFHPQHAVPISSWFSDTHDNELLDIIPLLEDLSSGNVLDVGSV
LDVTI"
gene complement(181789..183405)
/gene="YEH2"
/locus_tag="YLR020C"
/db_xref="GeneID:850707"
mRNA complement(181789..183405)
/gene="YEH2"
/locus_tag="YLR020C"
/product="Yeh2p"
/transcript_id="NM_001181907.1"
/db_xref="GI:296146558"
/db_xref="GeneID:850707"
CDS complement(181789..183405)
/gene="YEH2"
/locus_tag="YLR020C"
/EC_number="3.1.1.13"
/note="Steryl ester hydrolase, catalyzes steryl ester
hydrolysis at the plasma membrane; involved in sterol
metabolism"
/codon_start=1
/product="Yeh2p"
/protein_id="NP_013120.1"
/db_xref="GI:6323048"
/db_xref="SGD:S000004010"
/db_xref="GeneID:850707"
/translation="MVNKVVDEVQRLVSAIILTSFMTGLFILSLWKNYVTVHFQHKND
PRDTRSSRTKIQPNDKKKKRPARHSRPLSISSTTPLDLQRDQENNIEYDRTVTSKLSM
TSNASLSENGDGNANIKMETNVNQAPYAAENPFQNIALAEDTKLVPDLKYYYKEYGID
IEEFEVETDDGFIIDLWHFKSRLNDGVEEVKREPILLLHGLLQSCGAFASSGRKSLAY
FLYESGFDVWLGNNRCGLNAKWNMKKLGNDHSKKWDWDMHQMVQYDLKALINYVLDST
GYAKLSLVAHSQGTTQGFMGLVNGEKLYASDFKLVDKLENFVALAPAVYPGPLLDEKA
FVRLMAKGIDSPWYFGRRSFIPLMMTMRKLMVGTKIFSFLSYIMFNYLFDWNDVLWDR
VLRDRNFLFSPVHISVKLMQWWLSPLPNKLSFKKGAEKIFPDKKTWFPIAKNDDDSGN
NLDNNKLHLNPKRQNSEEFPHIIMFIPKQDRLVDGERLINHFINHEANAVYKIWYIDE
YSHLDVLWAHDVIDRIGKPMIENLRFPNAR"
gene 183623..184162
/gene="IRC25"
/locus_tag="YLR021W"
/gene_synonym="DMP2; PBA3; POC3"
/db_xref="GeneID:850708"
mRNA 183623..184162
/gene="IRC25"
/locus_tag="YLR021W"
/gene_synonym="DMP2; PBA3; POC3"
/product="Irc25p"
/transcript_id="NM_001181908.1"
/db_xref="GI:296146559"
/db_xref="GeneID:850708"
CDS 183623..184162
/gene="IRC25"
/locus_tag="YLR021W"
/gene_synonym="DMP2; PBA3; POC3"
/note="Component of a heterodimeric Poc4p-Irc25p chaperone
involved in assembly of alpha subunits into the 20S
proteasome; may regulate formation of proteasome isoforms
with alternative subunits under different conditions"
/codon_start=1
/product="Irc25p"
/protein_id="NP_013121.1"
/db_xref="GI:6323049"
/db_xref="SGD:S000004011"
/db_xref="GeneID:850708"
/translation="MISYEFQTHLPKGKDSSLNASSENKELYVQATHFNNTILLQIRL
NGEMDSTYEVSSKGLNPILDINVPLAGNLGNTGGDYDDEEEEFVRDHLSDYQVVTKLG
DSADPKVPVVCVQIAELYRRVILPEVSGTMAQDNMQFSLLISMSSKIWRATKEQSADD
NDFGKLVFVLKCIKDMYAK"
gene complement(184174..184926)
/gene="SDO1"
/locus_tag="YLR022C"
/db_xref="GeneID:850709"
mRNA complement(184174..184926)
/gene="SDO1"
/locus_tag="YLR022C"
/product="Sdo1p"
/transcript_id="NM_001181909.1"
/db_xref="GI:296146560"
/db_xref="GeneID:850709"
CDS complement(184174..184926)
/gene="SDO1"
/locus_tag="YLR022C"
/note="Essential protein involved in ribosome maturation;
with Ria1p, promotes release of Tif6p from 60S ribosomal
subunits in the cytoplasm so that they can assemble with
40S subunits to generate mature ribosomes; ortholog of the
human protein (SBDS) responsible for autosomal recessive
Shwachman-Bodian-Diamond Syndrome; highly conserved across
archaea and eukaryotes"
/codon_start=1
/product="Sdo1p"
/protein_id="NP_013122.1"
/db_xref="GI:6323050"
/db_xref="SGD:S000004012"
/db_xref="GeneID:850709"
/translation="MPINQPSGQIKLTNVSLVRLKKARKRFEVACYQNKVQDYRKGIE
KDLDEVLQIHQVFMNVSKGLVANKEDLQKCFGTTNVDDVIEEIMHKGEIQLSEKERQL
MLNKVNNEMLTIVSAKCINPVSKKRYPPTMIHKALQELKFSPVINKPAKLQALEAIKL
LVSKQIIPIVRAKMKVKVAISEPSRQPELIEKISKLIASSPGESTKPELDPWTCTGLI
DPVNYRDLMTLCDKKGTVQVLDMAVIDNTTHN"
gene complement(185498..187129)
/gene="IZH3"
/locus_tag="YLR023C"
/db_xref="GeneID:850710"
mRNA complement(185498..187129)
/gene="IZH3"
/locus_tag="YLR023C"
/product="Izh3p"
/transcript_id="NM_001181910.1"
/db_xref="GI:296146561"
/db_xref="GeneID:850710"
CDS complement(185498..187129)
/gene="IZH3"
/locus_tag="YLR023C"
/note="Membrane protein involved in zinc ion homeostasis,
member of the four-protein IZH family, expression induced
by zinc deficiency; deletion reduces sensitivity to
elevated zinc and shortens lag phase, overexpression
reduces Zap1p activity"
/codon_start=1
/product="Izh3p"
/protein_id="NP_013123.1"
/db_xref="GI:6323051"
/db_xref="SGD:S000004013"
/db_xref="GeneID:850710"
/translation="MMDSSSKSLTQYIPSPMGSLSRLKQKGVDNFQKVKKSGKSIYNY
NYSKFVPHPFSTIDESVKHSESGRYDDLEIIRPTKEKEVTSSVYKRNSGKSLNTESQF
SLGDSDAATLVNSVATFKLNNASTSTSLVSSSSTVCSQAKSSLRSPTSRLNDTKIKEE
NNYISSVKDYCGPMRKSMVKTEILIEEPLNPTTDIKSFINSYNHGKAYSLGETQHLHY
YQLPFPWRENRYIIHGYRFYNTHSKSLLSIFNWYGWHNETSNIWSHLLGAIYIIYLAI
YDFPQSEVWRNSQVPPQARWIVFMFLAAALKCMLSSVFWHTFNGTSFLKLRSKFACVD
YSGITILITASILTTEFVTMYSCYWAMYTYMSISLALGVFGVFMNWSPRFDRPEARPL
RIRFFILLATMGVLSFLHLIFLTDLHYAATLFSPVTYKSVVWYLVGVVFYGSFIPERF
RSDVQVDKTIPTNYELSTDLEIITKQREIHFREVPTAHSKCSSCPSHAKSFKSLWWVD
YFGCSHTFWHFFVVLGVIGHYRAILDMFAKRWILS"
gene complement(187663..193281)
/gene="UBR2"
/locus_tag="YLR024C"
/db_xref="GeneID:850711"
mRNA complement(187663..193281)
/gene="UBR2"
/locus_tag="YLR024C"
/product="putative ubiquitin-protein ligase UBR2"
/transcript_id="NM_001181911.2"
/db_xref="GI:330443670"
/db_xref="GeneID:850711"
CDS complement(187663..193281)
/gene="UBR2"
/locus_tag="YLR024C"
/EC_number="6.3.2.-"
/note="Cytoplasmic ubiquitin-protein ligase (E3); required
for ubiquitylation of Rpn4p; mediates formation of a
Mub1p-Ubr2p-Rad6p complex"
/codon_start=1
/product="putative ubiquitin-protein ligase UBR2"
/protein_id="NP_013124.1"
/db_xref="GI:6323052"
/db_xref="SGD:S000004014"
/db_xref="GeneID:850711"
/translation="MEDSDLSITNIRDFLTELPKLAKCEYSETTSYLLWKTLNLRLKH
SDNDINWRSLVSILNSEAWENEKYRDILNGRKWRTLEFENDHHSVGNMHIGTACTRLC
FPSETIYYCFTCSTNPLYEICELCFDKEKHVNHSYVAKVVMRPEGRICHCGDPFAFND
PSDAFKCKNELNNIPISNDNSNVTDDENVISLLNYVLDFLIDVTVSYKEEAEAHSSER
KASSLMHPNQNSITDDIMEKHECEPLVNDENFVFFDNNWSNTRKEAHMEWAIQIEEEE
CNVHYMDLASTITRILNTPVEYAISITKALEDSHDVVTVLQSENFFEIDQIAKEFQKE
NIVVHVRKADDIFKRKLTDDLTDWLYSLCFKAATSLQNKYALRISMLDVWYSHFSKMR
VSPTNTNPDFSKINLLGGFLISNEDSDESWFKPWSLENIEDERISKILTNYNERLIRA
HSPNTVSHFYNFYGSRFQYIIINSINILSKKSKFKMLKIMASLFSLRDESRKFLAAQY
IDVYLSVLYDAVASDAKECQVTLMSILGQYTFQDPSIANMTISSGFIERTIRFAFTLM
AFNPEDLMSYLPISLYNGFKLPTETIRNRRTIICFKDLCTIMSANTVPEELLSNEAIF
NAIIESFSEFSNVLPLKRETKEHVEVENFDFSAFYFFFSSILIMTDGYTRSISLVKDA
AFRKQIVLKLLDVAQTREFESLTNSRKAISPDNASTNENDSNKATLSTVRETICNYVA
ETINFQVGVNTQYFFNPMSYLFKFVIQWSQCGRYEPIPASLTNYINLFEVFQDKQKAL
YISESALSTLVLIGQINVGFWVRNGTPITHQARMYTKYSMREFTYISDIFNVQFSMAM
CNPDELMVTYLSRWGLKHWANGVPMYDYPDTETTVAVVNECILLLIQLLTEVRSLVMK
SSKEGFERTFKSEIIHALCFDTCSYAQIVNCIPEHITKHPSFDIYLEKYANYTSPVSL
TDNGIFVLKEKYKDEIDPYYIGLSSSRRYDVEKNIRLNMANLKKMKYEDTFVPAKKVK
DLLKNTLFSGLYSISSVNTFGLFLKNTLDHIIKYDYDNLLPRVVHLIHLCVVNNLNEF
MGILWHEYAIVDTEFCHYHSIGSILYYCLLKDNFSESHGKIREIFRYLMETAPHVNVN
SYLREQTTSYTPGILWPTKEDKSHKDKEFERKKHLARLRKKKLMKKLAQQQMKFMENN
SVDTSDISTPRTTSPSLSPTRINAENSSNTINSCCDDDCVFCKMPKDDDVFVYFSYQE
RNICDHGIDFTNPTDVNRINSLFSGKQTKDSAIQENPQDDDGTRLKFTSCEPVLRACG
HGSHTKCLSGHMKSIRGIQNQTTKNIPLSYGSGLIYCPVCNSLSNSFLPKTNDIDKRT
SSQFFMCIEKRSEAEENLDPMSSICIKAAMILGDLQGKKVTTIEDAYKVVNSVFINTI
SNTELRLRSHKKEGKIVNMERISSQCILTLHLVCELKSFIYKKFVNSKTFSSEISRKI
WNWNEFLIKGNNVNLLLYMSQNFDNIDGGKTPQPPNLCIYEMFKRRFHQLLLLLARDM
MRVNFYKDCRNKIKISSNGSEEPSTSFSYLFNTFKKYVDLFKPDDVRFDFTSLEKIKD
FICSLLLESLSIFCRRTFLLFNIQYDDDGDGDNNNNRSNNFMDVKQREIELIFRYFKL
PNLTHFLKDFFYNELTQNIERYNDGNDNLRIQQVIYDMVQNINTRAYPSPEHIQLIEL
PLNLSKFSLDNDEISNKCDKYEIAVCLLCGQKCHIQKSIALQGYLQGECTDHMRNGCE
ITSAYGVFLMTGTNAIYLSYGKRGTFYAAPYLSKYGETNEDYKFGTPVYLNRARYANL
ANEIVFGNMIPHIVFRLTDGSADLGGWETM"
gene 194452..195174
/gene="SNF7"
/locus_tag="YLR025W"
/gene_synonym="DID1; RNS4; VPL5; VPS32"
/db_xref="GeneID:850712"
mRNA 194452..195174
/gene="SNF7"
/locus_tag="YLR025W"
/gene_synonym="DID1; RNS4; VPL5; VPS32"
/product="Snf7p"
/transcript_id="NM_001181912.1"
/db_xref="GI:296146563"
/db_xref="GeneID:850712"
CDS 194452..195174
/gene="SNF7"
/locus_tag="YLR025W"
/gene_synonym="DID1; RNS4; VPL5; VPS32"
/note="One of four subunits of the endosomal sorting
complex required for transport III (ESCRT-III); involved
in the sorting of transmembrane proteins into the
multivesicular body (MVB) pathway; recruited from the
cytoplasm to endosomal membranes"
/codon_start=1
/product="Snf7p"
/protein_id="NP_013125.1"
/db_xref="GI:6323053"
/db_xref="SGD:S000004015"
/db_xref="GeneID:850712"
/translation="MWSSLFGWTSSNAKNKESPTKAIVRLREHINLLSKKQSHLRTQI
TNQENEARIFLTKGNKVMAKNALKKKKTIEQLLSKVEGTMESMEQQLFSIESANLNLE
TMRAMQEGAKAMKTIHSGLDIDKVDETMDEIREQVELGDEISDAISRPLITGANEVDE
DELDEELDMLAQENANQETSKIVNNNVNAAPISENKVSLPSVPSNKIKQSENSVKDGE
EEEDEEDEDEKALRELQAEMGL"
gene complement(195450..196472)
/gene="SED5"
/locus_tag="YLR026C"
/db_xref="GeneID:850713"
mRNA complement(195450..196472)
/gene="SED5"
/locus_tag="YLR026C"
/product="Sed5p"
/transcript_id="NM_001181913.1"
/db_xref="GI:296146564"
/db_xref="GeneID:850713"
CDS complement(195450..196472)
/gene="SED5"
/locus_tag="YLR026C"
/note="cis-Golgi t-SNARE syntaxin required for vesicular
transport between the ER and the Golgi complex, binds at
least 9 SNARE proteins"
/codon_start=1
/product="Sed5p"
/protein_id="NP_013126.1"
/db_xref="GI:6323054"
/db_xref="SGD:S000004016"
/db_xref="GeneID:850713"
/translation="MNIKDRTSEFQQSVLSYKKRNKNFREQQRERLQEKESENFANNT
TGNGKSVSEFQKKASGIAHEISSTAQLLSKLAVLAKRKPMFNDNPVEIAELSFLIKRK
IYAIEQSLVQLSQLKKTDVNGNTSNQSSKQPSAVQHSKNVVNLLNTQMKNISGSFKDV
LEERQRLEMANKDRWQKLTTDTGHAPADDQTQSNHAADLTTYNNSNPFMTSLLDESSE
KNNNSSNQGELSFPQNDSQLMLMEEGQLSNNVYLQERNRAVETIESTIQEVGNLFQQL
ASMVQEQGEVIQRIDANVDDIDLNISGAQRELLKYFDRIKSNRWLAAKVFFIIFVFFV
IWVLVN"
gene complement(196829..198085)
/gene="AAT2"
/locus_tag="YLR027C"
/gene_synonym="ASP5"
/db_xref="GeneID:850714"
mRNA complement(196829..198085)
/gene="AAT2"
/locus_tag="YLR027C"
/gene_synonym="ASP5"
/product="aspartate transaminase AAT2"
/transcript_id="NM_001181914.1"
/db_xref="GI:296146565"
/db_xref="GeneID:850714"
CDS complement(196829..198085)
/gene="AAT2"
/locus_tag="YLR027C"
/gene_synonym="ASP5"
/EC_number="2.6.1.1"
/note="Cytosolic aspartate aminotransferase, involved in
nitrogen metabolism; localizes to peroxisomes in
oleate-grown cells"
/codon_start=1
/product="aspartate transaminase AAT2"
/protein_id="NP_013127.2"
/db_xref="GI:37362677"
/db_xref="SGD:S000004017"
/db_xref="GeneID:850714"
/translation="MSATLFNNIELLPPDALFGIKQRYGQDQRATKVDLGIGAYRDDN
GKPWVLPSVKAAEKLIHNDSSYNHEYLGITGLPSLTSNAAKIIFGTQSDAFQEDRVIS
VQSLSGTGALHISAKFFSKFFPDKLVYLSKPTWANHMAIFENQGLKTATYPYWANETK
SLDLNGFLNAIQKAPEGSIFVLHSCAHNPTGLDPTSEQWVQIVDAIASKNHIALFDTA
YQGFATGDLDKDAYAVRLGVEKLSTVSPVFVCQSFAKNAGMYGERVGCFHLALTKQAQ
NKTIKPAVTSQLAKIIRSEVSNPPAYGAKIVAKLLETPELTEQWHKDMVTMSSRITKM
RHALRDHLVKLGTPGNWDHIVNQCGMFSFTGLTPQMVKRLEETHAVYLVASGRASIAG
LNQGNVEYVAKAIDEVVRFYTIEAKL"
gene 198784..199389
/locus_tag="snR30"
/db_xref="GeneID:9164925"
ncRNA 198784..199389
/locus_tag="snR30"
/ncRNA_class="snoRNA"
/product="SNR30"
/note="H/ACA box small nucleolar RNA (snoRNA); essential
gene required for cleavage of 35S primary rRNA transcript
to release the precursor to the 18S rRNA"
/db_xref="SGD:S000007497"
/db_xref="GeneID:9164925"
gene complement(199540..201315)
/gene="ADE16"
/locus_tag="YLR028C"
/db_xref="GeneID:850715"
mRNA complement(199540..201315)
/gene="ADE16"
/locus_tag="YLR028C"
/product="bifunctional
phosphoribosylaminoimidazolecarboxamide
formyltransferase/IMP cyclohydrolase ADE16"
/transcript_id="NM_001181915.1"
/db_xref="GI:296146566"
/db_xref="GeneID:850715"
CDS complement(199540..201315)
/gene="ADE16"
/locus_tag="YLR028C"
/EC_number="2.1.2.3"
/EC_number="3.5.4.10"
/note="Enzyme of 'de novo' purine biosynthesis; contains
both 5-aminoimidazole-4-carboxamide ribonucleotide
transformylase and inosine monophosphate cyclohydrolase
activities; ADE16 has a paralog, ADE17, that arose from
the whole genome duplication; ade16 ade17 mutants require
adenine and histidine"
/codon_start=1
/product="bifunctional
phosphoribosylaminoimidazolecarboxamide
formyltransferase/IMP cyclohydrolase ADE16"
/protein_id="NP_013128.1"
/db_xref="GI:6323056"
/db_xref="SGD:S000004018"
/db_xref="GeneID:850715"
/translation="MGKYTKTAILSVYDKTGLLDLAKGLVENNVRILASGGTANMVRE
AGFPVDDVSSITHAPEMLGGRVKTLHPAVHAGILARNLEGDEKDLKEQHIDKVDFVVC
NLYPFKETVAKIGVTVQEAVEEIDIGGVTLLRAAAKNHSRVTILSDPNDYSIFLQDLS
KDGEISQDLRNRFALKAFEHTADYDAAISDFFRKQYSEGKAQLPLRYGCNPHQRPAQA
YITQQEELPFKVLCGTPGYINLLDALNSWPLVKELSASLNLPAAASFKHVSPAGAAVG
LPLSDVERQVYFVNDMEDLSPLACAYARARGADRMSSFGDFIALSNIVDVATAKIISK
EVSDGVIAPGYEPEALNILSKKKNGKYCILQIDPNYVPGQMESREVFGVTLQQKRNDA
IINQSTFKEIVSKNKALTEQAVIDLTVATLVLKYTQSNSVCYAKNGMVVGLGAGQQSR
IHCTRLAGDKTDNWWLRQHPKVLNMKWAKGIKRADKSNAIDLFVTGQRIEGPEKVDYE
SKFEEVPEPFTKEERLEWLSKLNNVSLSSDAFFPFPDNVYRAVQSGVKFITAPSGSVM
DKVVFQAADSFDIVYVENPIRLFHH"
gene complement(201976..202590)
/gene="RPL15A"
/locus_tag="YLR029C"
/gene_synonym="RPL10A"
/db_xref="GeneID:850716"
mRNA complement(201976..202590)
/gene="RPL15A"
/locus_tag="YLR029C"
/gene_synonym="RPL10A"
/product="ribosomal 60S subunit protein L15A"
/transcript_id="NM_001181916.1"
/db_xref="GI:296146567"
/db_xref="GeneID:850716"
CDS complement(201976..202590)
/gene="RPL15A"
/locus_tag="YLR029C"
/gene_synonym="RPL10A"
/note="Ribosomal 60S subunit protein L15A; binds to 5.8 S
rRNA; homologous to mammalian ribosomal protein L15, no
bacterial homolog; RPL15A has a paralog, RPL15B, that
arose from the whole genome duplication"
/codon_start=1
/product="ribosomal 60S subunit protein L15A"
/protein_id="NP_013129.1"
/db_xref="GI:6323057"
/db_xref="SGD:S000004019"
/db_xref="GeneID:850716"
/translation="MGAYKYLEELQRKKQSDVLRFLQRVRVWEYRQKNVIHRAARPTR
PDKARRLGYKAKQGFVIYRVRVRRGNRKRPVPKGATYGKPTNQGVNELKYQRSLRATA
EERVGRRAANLRVLNSYWVNQDSTYKYFEVILVDPQHKAIRRDARYNWICDPVHKHRE
ARGLTATGKKSRGINKGHKFNNTKAGRRKTWKRQNTLSLWRYRK"
gene 203290..204081
/locus_tag="YLR030W"
/db_xref="GeneID:850717"
mRNA 203290..204081
/locus_tag="YLR030W"
/product="hypothetical protein"
/transcript_id="NM_001181917.1"
/db_xref="GI:296146568"
/db_xref="GeneID:850717"
CDS 203290..204081
/locus_tag="YLR030W"
/codon_start=1
/product="hypothetical protein"
/protein_id="NP_013130.1"
/db_xref="GI:6323058"
/db_xref="SGD:S000004020"
/db_xref="GeneID:850717"
/translation="MEGEQIMEYVQETPIIPKRIIHYSIPKQMITKPAPHVEMTLVAN
TFRDMDLPQHPVIHDCWQNKEYSTQRYSGNVAQQRLSFEEHPNEECQNSVGLIKRVST
FFKKRPLSRKNSIKSIGDVKSEARNRGEGLLGEVDNLNEQNVRENLTSEHEKSPEGDS
KRYGLFSFEETPPIQVLEQGNINSELSSFKNTSLAENKRSSDSFVSLKPGEDEHSPLE
ISTCGNLTEREDLQSGEERFDSAAQNIKVASMKEKKKIFKGNKTD"
gene 204225..204785
/locus_tag="YLR031W"
/db_xref="GeneID:850718"
mRNA 204225..204785
/locus_tag="YLR031W"
/product="hypothetical protein"
/transcript_id="NM_001181918.1"
/db_xref="GI:296146569"
/db_xref="GeneID:850718"
CDS 204225..204785
/locus_tag="YLR031W"
/codon_start=1
/product="hypothetical protein"
/protein_id="NP_013131.1"
/db_xref="GI:6323059"
/db_xref="SGD:S000004021"
/db_xref="GeneID:850718"
/translation="MPVLNTRTSYPNIDFHGTKVSDVLDAFEFEKHDDPLRDKWNTLQ
FLEKSFESKFESASELIQGGELAAIKERNFQLAKLNNLCFRVRESIKRRQDLEKKLRT
LSQDTDNELLFLMLENERRKKSSVIIEFLSEIIREKSKRLTAEEQGFVNQNEVKPLIL
DLSARINRLNSILETKNTCIRRLSNQ"
gene 204991..208500
/gene="RAD5"
/locus_tag="YLR032W"
/gene_synonym="REV2; SNM2"
/db_xref="GeneID:850719"
mRNA 204991..208500
/gene="RAD5"
/locus_tag="YLR032W"
/gene_synonym="REV2; SNM2"
/product="Rad5p"
/transcript_id="NM_001181919.1"
/db_xref="GI:296146570"
/db_xref="GeneID:850719"
CDS 204991..208500
/gene="RAD5"
/locus_tag="YLR032W"
/gene_synonym="REV2; SNM2"
/EC_number="3.6.1.-"
/note="DNA helicase; proposed to promote replication fork
regression during postreplication repair by template
switching; RING finger containing ubiquitin ligase;
stimulates the synthesis of free and PCNA-bound
polyubiquitin chains by Ubc13p-Mms2p; required for
error-prone translesion synthesis; forms nuclear foci upon
DNA replication stress"
/codon_start=1
/product="DNA helicase RAD5"
/protein_id="NP_013132.1"
/db_xref="GI:6323060"
/db_xref="SGD:S000004022"
/db_xref="GeneID:850719"
/translation="MSHIEQEERKRFFNDDLDTSETSLNFKSENKESFLFANSHNDDD
DDVVVSVSDTTEGEGDRSIVPVRREIEEEGQNQFITELLRIIPEMPKDLVMELNEKFG
SQEEGLSLALSHYFDHNSGTSISKIPSSPNQLNTLSDTSNSTLSPSSFHPKRRRIYGF
RNQTRLEDKVTWKRFIGALQVTGMATRPTVRPLKYGSQMKLKRSSEEISATKVYDSRG
RKKASMASLVRIFDIQYDREIGRVSEDIAQILYPLLSSHEISFEVTLIFCDNKRLSIG
DSFILQLDCFLTSLIFEERNDGESLMKRRRTEGGNKREKDNGNFGRTLTETDEELESR
SKRLALLKLFDKLRLKPILDEQKALEKHKIELNSDPEIIDLDNDEICSNQVTEVHNNL
RDTQHEEETMNLNQLKTFYKAAQSSESLKSLPETEPSRDVFKLELRNYQKQGLTWMLR
REQEFAKAASDGEASETGANMINPLWKQFKWPNDMSWAAQNLQQDHVNVEDGIFFYAN
LHSGEFSLAKPILKTMIKGGILSDEMGLGKTVAAYSLVLSCPHDSDVVDKKLFDIENT
AVSDNLPSTWQDNKKPYASKTTLIVVPMSLLTQWSNEFTKANNSPDMYHEVYYGGNVS
SLKTLLTKTKTPPTVVLTTYGIVQNEWTKHSKGRMTDEDVNISSGLFSVNFYRIIIDE
GHNIRNRTTVTSKAVMALQGKCKWVLTGTPIINRLDDLYSLVKFLELDPWRQINYWKT
FVSTPFESKNYKQAFDVVNAILEPVLLRRTKQMKDKDGKPLVELPPKEVVIKRLPFSK
SQDLLYKFLLDKAEVSVKSGIARGDLLKKYSTILVHILRLRQVCCHPGLIGSQDENDE
DLSKNNKLVTEQTVELDSLMRVVSERFDNSFSKEELDAMIQRLKVKYPDNKSFQSLEC
SICTTEPMDLDKALFTECGHSFCEKCLFEYIEFQNSKNLGLKCPNCRNQIDACRLLAL
VQTNSNSKNLEFKPYSPASKSSKITALLKELQLLQDSSAGEQVVIFSQFSTYLDILEK
ELTHTFSKDVAKIYKFDGRLSLKERTSVLADFAVKDYSRQKILLLSLKAGGVGLNLTC
ASHAYMMDPWWSPSMEDQAIDRLHRIGQTNSVKVMRFIIQDSIEEKMLRIQEKKRTIG
EAMDTDEDERRKRRIEEIQMLFE"
gene 208761..210269
/gene="RSC58"
/locus_tag="YLR033W"
/db_xref="GeneID:850720"
mRNA 208761..210269
/gene="RSC58"
/locus_tag="YLR033W"
/product="Rsc58p"
/transcript_id="NM_001181920.1"
/db_xref="GI:296146571"
/db_xref="GeneID:850720"
CDS 208761..210269
/gene="RSC58"
/locus_tag="YLR033W"
/note="Component of the RSC chromatin remodeling complex;
RSC functions in transcriptional regulation and
elongation, chromosome stability, and establishing sister
chromatid cohesion; involved in telomere maintenance"
/codon_start=1
/product="Rsc58p"
/protein_id="NP_013133.1"
/db_xref="GI:6323061"
/db_xref="SGD:S000004023"
/db_xref="GeneID:850720"
/translation="MTESVGGNKLVDFLVNVQSILNAASVKCHVVDESFPAKFFEKNP
DKIYESYCKFIKNRSNSEGLIRNEDKLVLTTINKRFENGEYEPIQGGFYKLYHDIKLV
CTILIHFYPQGTRNYQLVDKFYKFSSELLLRECCRIGIALTQTNNIKSRSGKLLSGNE
MDEYDDDDATELDKIISYDFIKISMNYTVPISQTYQIRTKDMDLFSSIISKSNLDKRP
HELPNTNFKINNVLPQTDIENEAPRLGFVGANTSNIPDPTLPPTEMMTRFLHPNWYAL
PTTVWLKYGNYNSWAPSFNENGTVVDSTTRGLIWLERIGYMDLYEKNEKKVKQEELLN
TNEEGINRKQNDENNKNVDGKSNGVQDDGGDNDNDATIASANSESTENKEQFIIKLQN
LYNWTPSNYIGDDEIENFRNGTPDKLVSDSLLKLKRLRKERILNKVLKPTTEERELYF
KVKRILKEVILAKKVSKVPINNVRAFPVLQTNYNGSIPVVRAQPGRKRKHKK"
gene complement(210512..211933)
/gene="SMF3"
/locus_tag="YLR034C"
/db_xref="GeneID:850721"
mRNA complement(210512..211933)
/gene="SMF3"
/locus_tag="YLR034C"
/product="putative divalent metal ion transporter SMF3"
/transcript_id="NM_001181921.2"
/db_xref="GI:330443671"
/db_xref="GeneID:850721"
CDS complement(210512..211933)
/gene="SMF3"
/locus_tag="YLR034C"
/note="Putative divalent metal ion transporter involved in
iron homeostasis; transcriptionally regulated by metal
ions; member of the Nramp family of metal transport
proteins; protein abundance increases in response to DNA
replication stress"
/codon_start=1
/product="putative divalent metal ion transporter SMF3"
/protein_id="NP_013134.1"
/db_xref="GI:6323062"
/db_xref="SGD:S000004024"
/db_xref="GeneID:850721"
/translation="MRSYMQILQKFAKFIGPGILVSVAYMDPGNYATSVSGGAQYKYT
LLFSIFISNIFAVLLQCLCVKLGTITGYDLAENCRHNLPKKLNYTLYLFAEVAIIATD
LAEVVGTAIALQILFKIPLTWGVLLTVLDVLVILMFYTPNGQSLKKVRVFEFGVGILV
IGTCICFVLELFKVSIPDKAELFKGFLPSNIIFKEQQALYISLGILGATVMPHSLYLG
SSIVKPRLHDYDLKKYGKVNARPSLSAIKYTLNYAYAELIISLFLIATFVNSAILIVA
GATLSGQPEAEDADLLSIYKLLVHYISPAAGLIFALAMLCSGQSAGIICTLAGQIVSE
GFLQWSLPPWATRLCTRLIAIVPCLFVTLTMGEKGISDILNFSQVVLSLILPIVSAPL
IYFTANRKLMVVHDENGVVRAPADVNAIADETTPLNSKHSKIVDFTNSRLLTYTSVFV
WALIGSLNCYLVISYLLGADIHF"
gene complement(212369..214456)
/gene="MLH2"
/locus_tag="YLR035C"
/db_xref="GeneID:850722"
mRNA complement(212369..214456)
/gene="MLH2"
/locus_tag="YLR035C"
/product="mismatch repair protein MLH2"
/transcript_id="NM_001181922.1"
/db_xref="GI:296146573"
/db_xref="GeneID:850722"
CDS complement(212369..214456)
/gene="MLH2"
/locus_tag="YLR035C"
/note="Protein involved in the mismatch repair of certain
frameshift intermediates and involved in meiotic
recombination; forms a complex with Mlh1p"
/codon_start=1
/product="mismatch repair protein MLH2"
/protein_id="NP_013135.1"
/db_xref="GI:6323063"
/db_xref="SGD:S000004025"
/db_xref="GeneID:850722"
/translation="MTIHQLSPESQWKIVSSSFIYGPVAAVRELLDNSIDSGAKKVFI
DVDSTTGGCEYISVKDDGSGVDIIDRPSMCLEYTTSKMSSLGDISILTTLGFRGEALF
LLSNLCNQKGSMQVETKTADDVIGEKWLVDSKGGITNGKRYKVSCPVGTTVILRKLLG
GLRARYLEISSRPRKTFDELIYLINHYSLIHRNIRFYFSLVSLQKNGAIERKQMQETL
DPKISRARSLSLLARLKKPVPLNFIVEENFVIDEKINLDLILPRMVPESDVINIKRRF
KFLSVNERALSLNLETGKTISKLLSSIYRDFSLLDPMVWFINLNCDTKLLDVNIEPEK
NDVMIKSFEVIFKKIENKLKLLLEERIGIETNMLGDKHVQPSINEKTSPALVIPTPDA
ENEISKGCGAVSGKDKTDIPQKNSDLIVPTFYDEANLENTTIVAATPSPTKFSEDKAL
DEQTQLTISSYRSSSSGSMASEDSTNWRHNFQQELSENSEVAGAGSSTLPSSLTYNYI
ETIPENEDLELSKDASISNPFMITKIRNVNKKLSENLLEAKRTSCGDANKRGMPNERQ
LSNTEKKELIKLQQTYGKRNNTVDMTIPRNSKKKVTDNYIKKASCMHKTRPKLMHFSE
YTNNYVYTLKNEKIVKHDSDNFAKETLWLRSRDDATSPSSSLLQALRAHVKKPGHIEA
TTNEWCLFTPDSP"
gene complement(214883..214955)
/locus_tag="tA(UGC)L"
/db_xref="GeneID:850723"
tRNA complement(214883..214955)
/locus_tag="tA(UGC)L"
/product="tRNA-Ala"
/note="Alanine tRNA (tRNA-Ala), predicted by tRNAscan-SE
analysis; one of 5 nuclear tRNA genes containing the
tDNA-anticodon TGC (mature tRNA may be UGC or may contain
modified bases), decodes GCA and probably GCG codons into
alanine, one of 16 nuclear tRNAs for alanine"
/db_xref="SGD:S000006524"
/db_xref="GeneID:850723"
LTR complement(215080..215417)
/note="Ty1 LTR"
/db_xref="SGD:S000007065"
gene complement(215440..218907)
/locus_tag="YLR035C-A"
/db_xref="GeneID:850724"
mRNA complement(<215440..>218907)
/locus_tag="YLR035C-A"
/transcript_id="NM_001184318.1"
/db_xref="GI:296146574"
/db_xref="GeneID:850724"
CDS complement(215440..218907)
/locus_tag="YLR035C-A"
/note="Retrotransposon TYA Gag and TYB Pol genes;
polyprotein is processed to make a nucleocapsid-like
protein (Gag), reverse transcriptase (RT), protease (PR),
and integrase (IN); YLR035C-A is part of a mutant
retrotransposon"
/codon_start=1
/product="gag-pol fusion protein"
/protein_id="NP_013136.1"
/db_xref="GI:6323064"
/db_xref="SGD:S000007225"
/db_xref="GeneID:850724"
/translation="MLAHANAQTIRYSLKNNTITYFNESDVDWSSAIDYQCPDCLIGK
STKHRHIKGSRLKYQNSYEPFQYLHTDIFGPVHNLPKSAPSYFISFTDETTKFRWVYP
LHDRREDSILDVFTTILAFIKNQFQASVLVIQMDRGSEYTNRTLHKFLEKNGITPCYT
TTADSRAHGVAERLNRTLLDDCRTQLQCSGLPNHLWFSAIEFSTIVRNSLASPKSKKS
ARQHAGLAGLDISTLLPFGQPVIVNDHNPNSKIHPRGIPGYALHPSRNSYGYIIYLPS
LKKTVDTTNYVILQGKESRLDQFNYDALTFDEDLNRLTASYQSFIASNEIQQSDDLNI
ESDHDFQSDIELHPEQPRNVLSKAVSPTDSTPPSTHTEDSKRVSKTNIRAPREVDPNI
SESNILPSKKRSSTPQISDIESTGSGGMHRLDVPLLAPMSQSNTHESSHASKSKDFRH
SDSYSDNETNHTNVPISSTGGTNNKTVPQTSEQETEKRIIHRSPSIDTSSSESNSLHH
VVPIKTSDTCPKENTEESIIADLPLPDLPPEPPTELSDSFKELPPINSHQTNSSLGGI
GDSNAYTTINSKKRSLEDNETEIKVSRDTWNTKNMRSLEPPRSKKRIHLIAAVKAVKS
IKPIRTTLRYDEAITYNKDIKEKEKYIQAYHKEVNQLLKMKTWDTDRYYDRKEIDPKR
VINSMFIFNRKRGGTHKARFVARGDIQHPDTYDPGMQSNTVHHYALMTSLSLASDNNY
YITQLDISSAYLYADIKEELYIRPPPHLGMNDKLIRLKKSLYGLKQSGANWYETIKSY
LIKQCGMEEVRGWSCVFKNSQVTICLFVDDMILFSKDLNANKKIITTLKKQYDTKIIN
LGESDNEIQYDILGLEIKYQRGKYMKLGMENSLTEKIPKLNVPLNPKGRKLSAPGQPG
LYIDQQELELEEDDYKMKVHEMQKLIGLASYVGYKFRFDLLYYINTLAQHILFPSKQV
LDMTYELIQFIWNTRDKQLIWHKSKPVKPTNKLVVISDASYGNQPYYKSQIGNIYLLN
GKVIGGKSTKASLTCTSTTEAEIHAISESVPLLNNLSHLVQELNKKPITKGLLTDSKS
TISIIISNNEEKFRNRFFGTKAMRLRDEVSGNHLHVCYIETKKNIADVMTKPLPIKTF
KLLTNKWIH"
LTR complement(220668..221005)
/note="Ty1 LTR"
/db_xref="SGD:S000007066"
LTR 221006..221266
/note="Ty1 LTR"
/db_xref="SGD:S000007083"
gene complement(221521..222132)
/locus_tag="YLR036C"
/db_xref="GeneID:850725"
mRNA complement(221521..222132)
/locus_tag="YLR036C"
/product="hypothetical protein"
/transcript_id="NM_001181923.1"
/db_xref="GI:296146575"
/db_xref="GeneID:850725"
CDS complement(221521..222132)
/locus_tag="YLR036C"
/note="hypothetical protein predicted to have
transmembrane domains; interacts with HSP90 by yeast
two-hybrid analysis; YLR036C is not an essential protein"
/codon_start=1
/product="hypothetical protein"
/protein_id="NP_013137.1"
/db_xref="GI:6323065"
/db_xref="SGD:S000004026"
/db_xref="GeneID:850725"
/translation="MKEAELSATESQDEIPKSNSLLIIEKLTKAVCSLYFINCFMVPS
VDNLIEKYPKAIIIKIIDMILGAVTISLVIIVFFLYRKNGHFKNENKTKPKRCSKVVC
PSCAARKKYPKWFQLKYLLLVSMTAFSFYFCTKIRFFFKTDQTINLHRLSQLFRLQLG
WICTTALLFYFYDALILHSGFIEGYRCVNGKGAMSEGKTGQLN"
gene complement(222685..223059)
/gene="PAU23"
/locus_tag="YLR037C"
/gene_synonym="DAN2"
/db_xref="GeneID:850726"
mRNA complement(222685..223059)
/gene="PAU23"
/locus_tag="YLR037C"
/gene_synonym="DAN2"
/product="Pau23p"
/transcript_id="NM_001181924.1"
/db_xref="GI:296146576"
/db_xref="GeneID:850726"
CDS complement(222685..223059)
/gene="PAU23"
/locus_tag="YLR037C"
/gene_synonym="DAN2"
/note="Cell wall mannoprotein with similarity to Tir1p,
Tir2p, Tir3p, and Tir4p; member of the seripauperin
multigene family encoded mainly in subtelomeric regions;
expressed under anaerobic conditions, completely repressed
during aerobic growth"
/codon_start=1
/product="Pau23p"
/protein_id="NP_013138.1"
/db_xref="GI:6323066"
/db_xref="SGD:S000004027"
/db_xref="GeneID:850726"
/translation="MVKLTSIVAGVAAIAAGVAAAPATTTLSPSDERVNLVELGVYVS
DIRAHLAEYYMFQAAHPTETYPVEIAEAVFNYGDFTTMLTGIPADQVTRVITGVPWYS
TRLRPAISSALSKDGIYTAVPN"
gene complement(224921..225172)
/gene="COX12"
/locus_tag="YLR038C"
/db_xref="GeneID:850727"
mRNA complement(224921..225172)
/gene="COX12"
/locus_tag="YLR038C"
/product="cytochrome c oxidase subunit VIb"
/transcript_id="NM_001181925.1"
/db_xref="GI:296146577"
/db_xref="GeneID:850727"
CDS complement(224921..225172)
/gene="COX12"
/locus_tag="YLR038C"
/EC_number="1.9.3.1"
/note="Subunit VIb of cytochrome c oxidase; cytochrome c
oxidase is also known as respiratory Complex IV and is the
terminal member of the mitochondrial inner membrane
electron transport chain; required for assembly of
cytochrome c oxidase but not required for activity after
assembly; phosphorylated; easily released from the
intermembrane space, suggesting a loose association with
Complex IV"
/codon_start=1
/product="cytochrome c oxidase subunit VIb"
/protein_id="NP_013139.1"
/db_xref="GI:6323067"
/db_xref="SGD:S000004028"
/db_xref="GeneID:850727"
/translation="MADQENSPLHTVGFDARFPQQNQTKHCWQSYVDYHKCVNMKGED
FAPCKVFWKTYNALCPLDWIEKWDDQREKGIFAGDINSD"
gene complement(225426..228596)
/gene="RIC1"
/locus_tag="YLR039C"
/db_xref="GeneID:850728"
mRNA complement(225426..228596)
/gene="RIC1"
/locus_tag="YLR039C"
/product="Ric1p"
/transcript_id="NM_001181926.1"
/db_xref="GI:296146578"
/db_xref="GeneID:850728"
CDS complement(225426..228596)
/gene="RIC1"
/locus_tag="YLR039C"
/note="Protein involved in retrograde transport to the
cis-Golgi network; forms heterodimer with Rgp1p that acts
as a GTP exchange factor for Ypt6p; involved in
transcription of rRNA and ribosomal protein genes"
/codon_start=1
/product="Ric1p"
/protein_id="NP_013140.1"
/db_xref="GI:6323068"
/db_xref="SGD:S000004029"
/db_xref="GeneID:850728"
/translation="MFIKQSEKNTPKCLYKKKGKVRVLLTGSCKKLNTWKMHLWPVSP
PQLLRIPPRNAELGEGTKIDDCNILQSMTLPQANVLIMLTPTRVLIYNFKPMALVASH
ERTMASLKEFGDNRSMKRSAPYNDIIEGLISKKDSQYLLWHQGKLIFYVMTDKNFLLT
YQILKNCTNEIIFKEYGIPVIEPLLMSEEEANSAEYDYNNDDDTLTVFDKNSSSRIIQ
NGFGITKEKGFLHFLSNQENIDELPVKKLELRLKVVLKFDYEIIDMIGIKTFSKVGDG
RYEEVLIVLFPHGLQILTISDFKVSKSSLVEVKKGSKTIVCNKQLMVLSHDSVEKQTI
VSIIDIEKQAVEAIPLTDTPDELLTCLEVNGYLVVVYKEKIICFDTRIKKVSHSWKPP
FVIKLCDKINDKILLLVSEDSVNIHFYTEFGNLLFATYFDEDDYNGDNNNDNSKDKNE
KKAAEYKISDFVCLDKSLITVSHSGKYQVWKLWEEIKQTQFDFRNPKCYVLTNTNNDV
IIYSPVTSSSINNDNLQVIKLPTKTFNNHIAFVKINSSLRLFATYVSNKNILLIHNLE
TNMWSSFADQNVLDLHWLGDNYLVCHMKNDDGSTNLKCLQIPLQEANPDVELSDYVMW
EYNVPENTIVFSLHVNTLSRYKLLKMKSKNHNASEKQPDALLKTAEIILVTDTQTIVF
DVISTVHPCGLNIIKKFYQYLKINIPIDVLPNKIEWIINMKEGLLFFADRKFIKLGKV
DGGGWQTLTLLDNIEKIIDVIRDEIFVVQGHNYVVYSLEDLWDDKKPLVSIPIEEDLY
PISTTPETATTHTLHCIFNARFSKLVVKHQIYLDQLILAKLEDNTDLEDISHNYRFLK
PYKFALEKILSTKILRSDSLDDILKLIKMYDNTDPEHNISPPTHSGMLEIISNCLRKI
ETKYWNHLFTNLKMTPRDLLALCIEENEAKMLGVLLLVFLNYDEKDLGDDLHFKKSDL
GTEESKALNDNSTKKSEKSVTNLLKDEELMLKVLELLVTSAANATDPIKATDSWDMCF
QLIRLLKELDRENNTQLVQKALERFK"
gene complement(228908..229582)
/locus_tag="YLR040C"
/db_xref="GeneID:850730"
mRNA complement(228908..229582)
/locus_tag="YLR040C"
/product="hypothetical protein"
/transcript_id="NM_001181927.1"
/db_xref="GI:296146579"
/db_xref="GeneID:850730"
CDS complement(228908..229582)
/locus_tag="YLR040C"
/note="hypothetical protein; localizes to the cell wall;
predicted to be a GPI-attached protein; upregulated by
Mcm1p-Alpha1p transcription factor; partially overlaps the
dubious ORF YLR041W; mRNA identified as translated by
ribosome profiling data; YLR040C is not essential"
/codon_start=1
/product="hypothetical protein"
/protein_id="NP_013141.1"
/db_xref="GI:6323070"
/db_xref="SGD:S000004030"
/db_xref="GeneID:850730"
/translation="MIFAPSFSLIKNILLVSFLISHSFAAKTLTSSSNDDTLARSAAA
DADMAFFMEFLNDFDTAFPQYTSYMMQNHLTLPQPVADYYYHMVDLASTADLQSDIAQ
SFPFTQFQTFITAFPWYTSLLNKASATTIYLPQHFITGETEATMTNSSYASQKNSVSN
SVPFSTANAGQSMISMANEENSTTALISASNSSSTSRTSQSQNGAHAKSLYFPMALFG
IFAVAL"
gene complement(229966..230451)
/locus_tag="YLR042C"
/db_xref="GeneID:850731"
mRNA complement(229966..230451)
/locus_tag="YLR042C"
/product="hypothetical protein"
/transcript_id="NM_001181929.1"
/db_xref="GI:296146580"
/db_xref="GeneID:850731"
CDS complement(229966..230451)
/locus_tag="YLR042C"
/note="hypothetical protein; localizes to the cytoplasm;
YLL042C is not an essential gene"
/codon_start=1
/product="hypothetical protein"
/protein_id="NP_013143.1"
/db_xref="GI:6323071"
/db_xref="SGD:S000004032"
/db_xref="GeneID:850731"
/translation="MKISQFGSLAFAPIVLLQLFIVQAQLLTDSNAQDLNTALGQKVQ
YTFLDTGNSNDQLLHLPSTTSSSIITGSLAAANFTGSSSSSSIPKVTSSVITSINYQS
SNSTVVTQFTPLPSSSRNETKSSQTTNTISSSTSTGGVGSVKPCLYFVLMLETIAYLF
S"
rep_origin 231179..231421
/note="ARS1211;
Autonomously Replicating Sequence"
/db_xref="SGD:S000118471"
gene complement(231702..232013)
/gene="TRX1"
/locus_tag="YLR043C"
/gene_synonym="LMA1"
/db_xref="GeneID:850732"
mRNA complement(231702..232013)
/gene="TRX1"
/locus_tag="YLR043C"
/gene_synonym="LMA1"
/product="Trx1p"
/transcript_id="NM_001181930.1"
/db_xref="GI:296146581"
/db_xref="GeneID:850732"
CDS complement(231702..232013)
/gene="TRX1"
/locus_tag="YLR043C"
/gene_synonym="LMA1"
/note="Cytoplasmic thioredoxin isoenzyme; part of the
thioredoxin system which protects cells against oxidative
and reductive stress; forms LMA1 complex with Pbi2p; acts
as a cofactor for Tsa1p, required for ER-Golgi transport
and vacuole inheritance; protein abundance increases in
response to DNA replication stress"
/codon_start=1
/product="Trx1p"
/protein_id="NP_013144.1"
/db_xref="GI:6323072"
/db_xref="SGD:S000004033"
/db_xref="GeneID:850732"
/translation="MVTQFKTASEFDSAIAQDKLVVVDFYATWCGPCKMIAPMIEKFS
EQYPQADFYKLDVDELGDVAQKNEVSAMPTLLLFKNGKEVAKVVGANPAAIKQAIAAN
A"
gene complement(232390..234081)
/gene="PDC1"
/locus_tag="YLR044C"
/db_xref="GeneID:850733"
mRNA complement(232390..234081)
/gene="PDC1"
/locus_tag="YLR044C"
/product="indolepyruvate decarboxylase 1"
/transcript_id="NM_001181931.1"
/db_xref="GI:296146582"
/db_xref="GeneID:850733"
CDS complement(232390..234081)
/gene="PDC1"
/locus_tag="YLR044C"
/EC_number="4.1.1.74"
/EC_number="4.1.1.72"
/EC_number="4.1.1.-"
/EC_number="4.1.1.1"
/note="Major of three pyruvate decarboxylase isozymes, key
enzyme in alcoholic fermentation, decarboxylates pyruvate
to acetaldehyde; subject to glucose-, ethanol-, and
autoregulation; involved in amino acid catabolism"
/codon_start=1
/product="indolepyruvate decarboxylase 1"
/protein_id="NP_013145.1"
/db_xref="GI:6323073"
/db_xref="SGD:S000004034"
/db_xref="GeneID:850733"
/translation="MSEITLGKYLFERLKQVNVNTVFGLPGDFNLSLLDKIYEVEGMR
WAGNANELNAAYAADGYARIKGMSCIITTFGVGELSALNGIAGSYAEHVGVLHVVGVP
SISAQAKQLLLHHTLGNGDFTVFHRMSANISETTAMITDIATAPAEIDRCIRTTYVTQ
RPVYLGLPANLVDLNVPAKLLQTPIDMSLKPNDAESEKEVIDTILALVKDAKNPVILA
DACCSRHDVKAETKKLIDLTQFPAFVTPMGKGSIDEQHPRYGGVYVGTLSKPEVKEAV
ESADLILSVGALLSDFNTGSFSYSYKTKNIVEFHSDHMKIRNATFPGVQMKFVLQKLL
TTIADAAKGYKPVAVPARTPANAAVPASTPLKQEWMWNQLGNFLQEGDVVIAETGTSA
FGINQTTFPNNTYGISQVLWGSIGFTTGATLGAAFAAEEIDPKKRVILFIGDGSLQLT
VQEISTMIRWGLKPYLFVLNNDGYTIEKLIHGPKAQYNEIQGWDHLSLLPTFGAKDYE
THRVATTGEWDKLTQDKSFNDNSKIRMIEIMLPVFDAPQNLVEQAKLTAATNAKQ"
gene complement(235037..237703)
/gene="STU2"
/locus_tag="YLR045C"
/db_xref="GeneID:850734"
mRNA complement(235037..237703)
/gene="STU2"
/locus_tag="YLR045C"
/product="Stu2p"
/transcript_id="NM_001181932.1"
/db_xref="GI:296146583"
/db_xref="GeneID:850734"
CDS complement(235037..237703)
/gene="STU2"
/locus_tag="YLR045C"
/note="Microtubule-associated protein (MAP) of the
XMAP215/Dis1 family; regulates microtubule dynamics during
spindle orientation and metaphase chromosome alignment;
interacts with spindle pole body component Spc72p"
/codon_start=1
/product="Stu2p"
/protein_id="NP_013146.1"
/db_xref="GI:6323074"
/db_xref="SGD:S000004035"
/db_xref="GeneID:850734"
/translation="MSGEEEVDYTTLPLEERLTYKLWKARLEAYKELNQLFRNSVGDI
SRDDNIQIYWRDPTLFAQYITDSNVVAQEQAIVALNSLIDAFASSSLKNAHNITLIST
WTPLLVEKGLTSSRATTKTQSMSCILSLCGLDTSITQSVELVIPFFEKKLPKLIAAAA
NCVYELMAAFGLTNVNVQTFLPELLKHVPQLAGHGDRNVRSQTMNLIVEIYKVTGNNS
DLLEEILFKKLKPIQVKDLHKLFAKVGDEPSSSKMLFEWEKRELEKKRSQEEEARKRK
SILSNDEGEYQIDKDGDTLMGMETDMPPSKQQSGVQIDTFSMLPEETILDKLPKDFQE
RITSSKWKDRVEALEEFWDSVLSQTKKLKSTSQNYSNLLGIYGHIIQKDANIQAVALA
AQSVELICDKLKTPGFSKDYVSLVFTPLLDRTKEKKPSVIEAIRKALLTICKYYDPLA
SSGRNEDMLKDILEHMKHKTPQIRMECTQLFNASMKEEKDGYSTLQRYLKDEVVPIVI
QIVNDTQPAIRTIGFESFAILIKIFGMNTFVKTLEHLDNLKRKKIEETVKTLPNFSIA
SGSTHSTIETNKQTGPMENKFLLKKSSVLPSKRVASSPLRNDNKSKVNPIGSVASASK
PSMVAANNKSRVLLTSKSLATPKNVVANSTDKNEKLIEEYKYRLQKLQNDEMIWTKER
QSLLEKMNNTENYKIEMIKENEMLREQLKEAQSKLNEKNIQLRSKEIDVNKLSDRVLS
LENELRNMEIELDRNKKRNDTNLQSMGTISSYSIPSSTVSSNYGVKSLSSALPFKEEE
DVRRKEDVNYERRSSESIGDLPHRVNSLNIRPYRKNGTGVSSVSDDLDIDFNDSFASE
ESYKRAAAVTSTLKARIEKMKAKSRREGTTRT"
gene complement(238001..238813)
/locus_tag="YLR046C"
/db_xref="GeneID:850735"
mRNA complement(238001..238813)
/locus_tag="YLR046C"
/product="hypothetical protein"
/transcript_id="NM_001181933.1"
/db_xref="GI:296146584"
/db_xref="GeneID:850735"
CDS complement(238001..238813)
/locus_tag="YLR046C"
/note="Putative membrane protein; member of the fungal
lipid-translocating exporter (LTE) family of proteins;
transcription is activated by paralogous transcription
factors Yrm1p and Yrr1p along with genes involved in
multidrug resistance"
/codon_start=1
/product="hypothetical protein"
/protein_id="NP_013147.1"
/db_xref="GI:6323075"
/db_xref="SGD:S000004036"
/db_xref="GeneID:850735"
/translation="MATHTSKRRIHRWENNELSEENSTIIYFPARGLMWTHFPFVLGI
CLEFVGYVLKIVFINSPSISTFIAQSVLLLIAPSLYALSIFMLFSKMARLILMEAYML
IPAKFSTVSFVVADMIGRVLQAVGGGLLSSWNSRNTGRILIIVGLFIQIFCYTFLTFS
QLFLHYKMKATPSKIVRDSNEWFQYNFILLAGILLVNGRTIVRVVQFLMGLQSYIGQH
EWCLYVFDTVLMFLLPLIFLATFRARNLFKLQDKSVNIQLNKLLDKESVSED"
gene complement(239347..241407)
/gene="FRE8"
/locus_tag="YLR047C"
/db_xref="GeneID:850736"
mRNA complement(239347..241407)
/gene="FRE8"
/locus_tag="YLR047C"
/product="Fre8p"
/transcript_id="NM_001181934.1"
/db_xref="GI:296146585"
/db_xref="GeneID:850736"
CDS complement(239347..241407)
/gene="FRE8"
/locus_tag="YLR047C"
/EC_number="1.16.1.7"
/note="Protein with sequence similarity to iron/copper
reductases, involved in iron homeostasis; deletion mutant
has iron deficiency/accumulation growth defects;
expression increased in the absence of copper-responsive
transcription factor Mac1p"
/codon_start=1
/product="Fre8p"
/protein_id="NP_013148.1"
/db_xref="GI:6323076"
/db_xref="SGD:S000004037"
/db_xref="GeneID:850736"
/translation="MNLKSIVSWFKEHLPSFDVDVDKHFRTLRVRKYSQICLLISFII
ICVIIPLMNYLLLTDKFFKICHHLKHHVFNRRSWVHKTHMYHKQSLQLCLICFVFTSF
FVIQGANGDLLEITKRMGRISVALMPPLLFLTLRPSPLPHTLYLALLPLHKWISRIVV
LESILHTWFYLYYMYINDTLYVKMRKLPNIYGVIALGLFLLIAITSVRYARRWSYRVF
YYVHYVSTWLILVFLHYHARPGISYYTTLNVLILTGQIVYRLHITNVTRVTIVPISSS
LSLLEFPLTDLPKKPILPGGHLRINIYHRNFLRRFFSHLIPFQHPFTIASIPSDNLVR
LIIRNGHFPLRTNEKYYITGAFEPELSFISKPTVPFNITTKSSKNPFRNNSSALINSP
LNFLIKAQRVFMCVGGSGISFGLPLLRILNFNGVNVRLLWVSRDYKDLEVLNHFKNNF
EGMEIYISGTEGNEQDIEIDYIDYHDCAADINDEVRSISSSGRVSELGDNSMLSDGNP
QPTEPNENTALLSKKSTLRNHHPPKTSDIPDINADDEIDFTYAFSRSKSRKNTAQGTL
TTHSSFNGSSVFRQPKIIEPPAQDPCLEAAPKKIRIPAGVKVFFGRPTLGDKDYEWCL
QTECDAETDSIQCCRWANQGRDHAEYLSQVWVLAAGPRGLIESTKRWATDGGLHFHGE
SFAL"
gene 242232..243349
/gene="RPS0B"
/locus_tag="YLR048W"
/gene_synonym="NAB1B; YST2"
/db_xref="GeneID:850737"
mRNA join(242232..242321,242681..243349)
/gene="RPS0B"
/locus_tag="YLR048W"
/gene_synonym="NAB1B; YST2"
/product="ribosomal 40S subunit protein S0B"
/transcript_id="NM_001181935.1"
/db_xref="GI:296146586"
/db_xref="GeneID:850737"
CDS join(242232..242321,242681..243349)
/gene="RPS0B"
/locus_tag="YLR048W"
/gene_synonym="NAB1B; YST2"
/note="Protein component of the small (40S) ribosomal
subunit; RPS0B has a paralog, RPS0A, that arose from the
whole genome duplication; required for maturation of 18S
rRNA along with Rps0Ap; deletion of either RPS0 gene
reduces growth rate, deletion of both genes is lethal;
homologous to human ribosomal protein SA and bacterial S2"
/codon_start=1
/product="ribosomal 40S subunit protein S0B"
/protein_id="NP_013149.1"
/db_xref="GI:6323077"
/db_xref="SGD:S000004038"
/db_xref="GeneID:850737"
/translation="MSLPATFDLTPEDAQLLLAANTHLGARNVQVHQEPYVFNARPDG
VHVINVGKTWEKLVLAARIIAAIPNPEDVVAISSRTYGQRAVLKFAAHTGATPIAGRF
TPGSFTNYITRSFKEPRLVIVTDPRLDAQAIKEASYVNIPVIALTDLDSPSEFVDVAI
PCNNRGKHSIGLIWYLLAREVLRLRGALVDRTQPWSIMPDLYFYRNPEEVEQVAEEAA
AAEEGEEEEVKEEVTEGQAEATEWAEENADNVEW"
gene complement(243886..245172)
/locus_tag="YLR049C"
/db_xref="GeneID:850738"
mRNA complement(243886..245172)
/locus_tag="YLR049C"
/product="hypothetical protein"
/transcript_id="NM_001181936.1"
/db_xref="GI:296146587"
/db_xref="GeneID:850738"
CDS complement(243886..245172)
/locus_tag="YLR049C"
/codon_start=1
/product="hypothetical protein"
/protein_id="NP_013150.1"
/db_xref="GI:6323078"
/db_xref="SGD:S000004039"
/db_xref="GeneID:850738"
/translation="MVNNIMHEYVPPSQRLFHSRHRITRNDLKEEALHSGTTDWTTIL
DTTIDKDTNLISYAVPIIDNFAIPRANSQGSPVAPSPNHRSTMYSSSSSSASSVFSDG
LFTPNNNRNSSGSSSLVIRPQKNLSVDSLIQENKRKINSEKESLSLIANNNDETLCTH
TDPSIQNLIKSETKRNILNLKFQNRNLFRRELKLEKFWSNLRSCHTSGDETDLLLVIS
KHNLYWFGIPNDFRLPIYKRCLYHYSELDEAGFFSQYANNSLYLAIRKCCNNEEQETL
SRSIFINLTKNVTWLNSRFDDNKDNKNSYTVTEGKFYQDFPNLYYHLKDKLKLNVIMD
FIKPVIRNFMTNALNKHKLDGIGLELLDILIVTTYYGPNKINAFLMDTFILNLLKQCH
YKFFVSNISELVIQISKIDCDLVILLEDLRSRIDLD"
gene complement(245587..246072)
/locus_tag="YLR050C"
/db_xref="GeneID:850739"
mRNA complement(245587..246072)
/locus_tag="YLR050C"
/product="hypothetical protein"
/transcript_id="NM_001181937.1"
/db_xref="GI:296146588"
/db_xref="GeneID:850739"
CDS complement(245587..246072)
/locus_tag="YLR050C"
/note="hypothetical protein; green fluorescent protein
(GFP)-fusion protein localizes to the endoplasmic
reticulum; YLR050C is not an essential gene"
/codon_start=1
/product="hypothetical protein"
/protein_id="NP_013151.1"
/db_xref="GI:6323079"
/db_xref="SGD:S000004040"
/db_xref="GeneID:850739"
/translation="MKLGHREQQFYLWYFIVHIPITIFIDSSVVIPAKWQLGIAQKVV
SDHIAKQHDFLLSEKPEWLYWFVVLELVLQLPLFVYFVNKFWNSSELQVNTNSRLKKW
LRIYGWNASLTTLICIVVIFKRGYIPYDVLKTSLSMTQKCQLASVYLPTFLIPLRLCF
V"
gene complement(246324..246977)
/gene="FCF2"
/locus_tag="YLR051C"
/db_xref="GeneID:850740"
mRNA complement(246324..246977)
/gene="FCF2"
/locus_tag="YLR051C"
/product="Fcf2p"
/transcript_id="NM_001181938.1"
/db_xref="GI:296146589"
/db_xref="GeneID:850740"
CDS complement(246324..246977)
/gene="FCF2"
/locus_tag="YLR051C"
/note="Essential nucleolar protein involved in the early
steps of 35S rRNA processing; interacts with Faf1p; member
of a transcriptionally co-regulated set of genes called
the RRB regulon"
/codon_start=1
/product="Fcf2p"
/protein_id="NP_013152.1"
/db_xref="GI:6323080"
/db_xref="SGD:S000004041"
/db_xref="GeneID:850740"
/translation="MDQSVEDLFGALRDASASLEVKNSAKEQVSLQQEDVLQIGNNDD
EVEIESKFQEIETNLKKLPKLETGFDALANKKKKKNVLPSVETEDKRKPNKSDKNDND
WFTLPKPDDNMRREVQRDLLLIKHRAALDPKRHYKKQRWEVPERFAIGTIIEDKSEFY
SSRMNRKERKSTILETLMGDEASNKYFKRKYNEIQEKSTSGRKAHYKKMKEMRKKRR"
gene 247201..247953
/gene="IES3"
/locus_tag="YLR052W"
/db_xref="GeneID:850741"
mRNA 247201..247953
/gene="IES3"
/locus_tag="YLR052W"
/product="Ies3p"
/transcript_id="NM_001181939.1"
/db_xref="GI:296146590"
/db_xref="GeneID:850741"
CDS 247201..247953
/gene="IES3"
/locus_tag="YLR052W"
/note="Subunit of the INO80 chromatin remodeling complex"
/codon_start=1
/product="Ies3p"
/protein_id="NP_013153.1"
/db_xref="GI:6323081"
/db_xref="SGD:S000004042"
/db_xref="GeneID:850741"
/translation="MKFEDLLATNKQVQFAHAATQHYKSVKTPDFLEKDPHHKKFHNA
DGLNQQGSSTPSTATDANAASTASTHTNTTTFKRHIVAVDDISKMNYEMIKNSPGNVI
TNANQDEIDISTLKTRLYKDNLYAMNDNFLQAVNDQIVTLNAAEQDQETEDPDLSDDE
KIDILTKIQENLLEEYQKLSQKERKWFILKELLLDANVELDLFSNRGRKASHPIAFGA
VAIPTNVNANSLAFNRTKRRKINKNGLLENIL"
gene complement(248100..248426)
/locus_tag="YLR053C"
/db_xref="GeneID:850742"
mRNA complement(248100..248426)
/locus_tag="YLR053C"
/product="hypothetical protein"
/transcript_id="NM_001181940.1"
/db_xref="GI:296146591"
/db_xref="GeneID:850742"
CDS complement(248100..248426)
/locus_tag="YLR053C"
/codon_start=1
/product="hypothetical protein"
/protein_id="NP_013154.1"
/db_xref="GI:6323082"
/db_xref="SGD:S000004043"
/db_xref="GeneID:850742"
/translation="MDMLHNKCSDAIKSTSNSNLSNEVDKQKLQYDDLGNTGFSELFE
MESQDNNDSIEDFLFFNINLTQEVEFENQRQYEHTKKTKKHNPFYVPSEVVREMVKKH
ALNGRI"
gene complement(248717..250978)
/gene="OSW2"
/locus_tag="YLR054C"
/db_xref="GeneID:850743"
mRNA complement(join(248717..250860,250948..250978))
/gene="OSW2"
/locus_tag="YLR054C"
/product="Osw2p"
/transcript_id="NM_001181941.1"
/db_xref="GI:296146592"
/db_xref="GeneID:850743"
CDS complement(join(248717..250860,250948..250978))
/gene="OSW2"
/locus_tag="YLR054C"
/note="hypothetical protein proposed to be involved in the
assembly of the spore wall"
/codon_start=1
/product="Osw2p"
/protein_id="NP_013155.2"
/db_xref="GI:37362678"
/db_xref="SGD:S000004044"
/db_xref="GeneID:850743"
/translation="MEENQLTCLIVGETPAAQFLGWRLSLSNSFIILVSQYVSSDELV
AWKSTKLGANFYTPNILTKDIKELHHKLKHNGANTYSIDIVLVSAISLQSFETTCRLL
SDYTNDNTTVLISTDFGCELEPIAISYFGGKCKCVISISCEVECRQLSLGSYALVNDD
QCVITLGLTYCDANFEASPTILENTKAASLELQGIKGSNVRRFLLGLTVAKWMKSKLI
LDPKQMALKMWELLIPKISLNILSIIYEQFDYEKMLENKSTEIIFKDLVKELLGICFA
QCGSKIARFLLVKSQGEEEINFGKIVEYCKGKKLQLINSTANEHPEYLSLPFEPYCFY
HRFEYPAQILLHQPIILAKKYGVSCSNLNFLYGFYTRLLTLSGLSINGGRCEHALSML
DSRIGGGINVASGINSGQDFTDGDNEDQDKGKNRVDKNVKEGSFISLTQRFTMTSPLG
VNDPALPADLEKLYLGAEYISNCDANTSGGQKRVKSPTKADTGYDDKHLPDDTIHTFE
DEYLADEDDFSCLGIDKRSSTKPTKPLEKFGVVAVPHFIRRFSIKRSSKDKSNDMKRP
YTTSSLELQLRSNHFMFAKEYQDLHRQLYYEVKPRTQSELDARRRNYSELESQMWKIK
HRFNIHRGALPRPRTNPYELLLDHIDVLNRGNTGDILRFTTSRYGGVDTYDSILRDQS
TIMELLDKRCAYSPPVLFDNEAKERDHDRDCYQDYNHDHRSH"
gene complement(251272..253080)
/gene="SPT8"
/locus_tag="YLR055C"
/db_xref="GeneID:850744"
mRNA complement(251272..253080)
/gene="SPT8"
/locus_tag="YLR055C"
/product="Spt8p"
/transcript_id="NM_001181942.1"
/db_xref="GI:296146593"
/db_xref="GeneID:850744"
CDS complement(251272..253080)
/gene="SPT8"
/locus_tag="YLR055C"
/note="Subunit of the SAGA transcriptional regulatory
complex but not present in SAGA-like complex SLIK/SALSA,
required for SAGA-mediated inhibition at some promoters"
/codon_start=1
/product="Spt8p"
/protein_id="NP_013156.1"
/db_xref="GI:6323084"
/db_xref="SGD:S000004045"
/db_xref="GeneID:850744"
/translation="MDEVDDILINNQVVDDEEDDEEMLSGLENDSKQDLEGNDDGGED
EEDDDDDDEDDDDDEDEREDDDEQEDDDGEDDAARMDKTATPTNEHQHDEQKAAAAGA
GGAGDSGDAVTKIGSEDVKLSDVDGGVGSREASSSTHEASANGEVYEYYKHMLNAAQI
ADSYNIYPTAAIPIQTHVNALAVSRGLKYLFLGGSDGYIRKYDLLNTLEGKLSLTILQ
KHSLAESIQNAGILQSYWENEIPQKKSEMKLSANKTDYEPKVSPVHSLEVQSECLFIL
SGLQNGGITMQGVRYMEGSIAHYFKGRNGHTQIVNILRLNGQEDRFLSGSWDKRLLEW
DLQTGDIVNEFKKSRSELSSLEMRPLYSSVDVSGNVNSGKENENADDDMDSLFGDEDE
DEKQDAGNEPVETGDGSNGEENKEQISEESLNIVYDESVFMTSGLNGSVHIWDRRMTQ
SPALSLERGAGVPPWCLSACWGVDGDHVYAGRRNACVEQFDLKMPSKPIHNLKLPSIS
GPVSCVKAMPNNKHLLCASRDNIRLYNVEIAVDASNSTTKSSKVPFLIVPGHHGGIIS
NLYLDPTSRFIISTSGNRGWQGNSTDTTLIYDIDLE"
gene 253861..254958
/gene="ERG3"
/locus_tag="YLR056W"
/gene_synonym="PSO6; SYR1"
/db_xref="GeneID:850745"
mRNA 253861..254958
/gene="ERG3"
/locus_tag="YLR056W"
/gene_synonym="PSO6; SYR1"
/product="C-5 sterol desaturase"
/transcript_id="NM_001181943.1"
/db_xref="GI:296146594"
/db_xref="GeneID:850745"
CDS 253861..254958
/gene="ERG3"
/locus_tag="YLR056W"
/gene_synonym="PSO6; SYR1"
/EC_number="1.3.3.-"
/note="C-5 sterol desaturase, glycoprotein that catalyzes
the introduction of a C-5(6) double bond into episterol, a
precursor in ergosterol biosynthesis; mutants are viable,
but cannot grow on non-fermentable carbon sources;
substrate of the HRD ubiquitin ligase"
/codon_start=1
/product="C-5 sterol desaturase"
/protein_id="NP_013157.1"
/db_xref="GI:6323085"
/db_xref="SGD:S000004046"
/db_xref="GeneID:850745"
/translation="MDLVLEVADHYVLDDLYAKVLPASLAANIPVKWQKLLGLNSGFS
NSTILQETLNSKNAVKECRRFYGQVPFLFDMSTTSFASLLPRSSILREFLSLWVIVTI
FGLLLYLFTASLSYVFVFDKSIFNHPRYLKNQMAMEIKLAVSAIPWMSMLTVPWFVME
LNGHSKLYMKIDYENHGVRKLIIEYFTFIFFTDCGVYLAHRWLHWPRVYRALHKPHHK
WLVCTPFASHSFHPVDGFLQSISYHIYPLILPLHKVSYLILFTFVNFWTVMIHDGQYL
SNNPAVNGTACHTVHHLYFNYNYGQFTTLWDRLGGSYRRPDDSLFDPKLRDAKETWDA
QVKEVEHFIKEVEGDDNDRIYENDPNTKKNN"
gene 255306..257855
/gene="MNL2"
/locus_tag="YLR057W"
/db_xref="GeneID:850746"
mRNA 255306..257855
/gene="MNL2"
/locus_tag="YLR057W"
/product="Mnl2p"
/transcript_id="NM_001181944.1"
/db_xref="GI:296146595"
/db_xref="GeneID:850746"
CDS 255306..257855
/gene="MNL2"
/locus_tag="YLR057W"
/EC_number="3.2.1.-"
/note="Putative mannosidase involved in ER-associated
protein degradation; localizes to the endoplasmic
reticulum; sequence similarity with seven-hairpin
glycosidase (GH47) family members, such as Mns1p and
Mnl1p, that hydrolyze 1,2-linked alpha-D-mannose residues;
non-essential gene"
/codon_start=1
/product="Mnl2p"
/protein_id="NP_013158.1"
/db_xref="GI:6323086"
/db_xref="SGD:S000004047"
/db_xref="GeneID:850746"
/translation="MSIARLVYSLFRRVRSVLLLFITISLLFYYTFQNEIDILNSYAL
NDSLPSINNYEHNTEGSSKLDPPDLSSTGSDRIATDKENGNVAVDLSDPATLREKNKY
FPLLLKGSSHQIGSNLPISSLLTYKEKYPVLFEYSSPSLTSISQNDVHKIQPAMQLPP
DVDMIKQIKDIFMKSWNQEQLLLKSNLRRESTWPIDLIDSLDTLYLCGETKLFQDSVN
IIEDFDFRVPPLAMEVIDIPDITTRVLEGLLSAYELSMDKRLLNKAKHVADFILRSFD
TPNRIPILKYFWKSDLRNRFPDRTVPSGQLTTMALAFIRLSQLTRLNKYFDAVERVFT
TIRQSYNEFDMEFMLPDVVDASGCQLLTQEEIENGAHLKGSSIMKSINENFKFVHCQQ
LGKFLNPPIDDNSLQEQSQYQAYRINEKTVPILENLFKINDLFQSSYDILDGSSKNAN
AATMDPSIGSEVEAVDEIIEKRNFKDGTKKDSTKNTVGDKSLIDSQTFLTNSISNIFK
FMTFRPMLPKQTENKKFNFLNSILTKSQFMPTTNELDVTIRKSYDVSLYSCRLGGILG
LSSRVPHRGGVNTKYILPSSLLEMSEIITESCFMLMEEFDGLLPQKFELDPCTDETNG
NCEFNGETKSRMIANGEYETFENDLDVGIKVSNYGKGGNDQKAKRNVLSKDGITETQN
IKGDTVGSSKSIAEIDGDEVTQIRRVFTLGKDIKPHITTDDTMGSQWKNHPDWPFWVN
KVESRRLLDSNIIESIFYMYRISGEQKWRSMGKQSFGILMQELMELNSGAKGLWQIKE
FYENGEKVNNDLPSYWFSRTLKYYLLLFSDGDKVSLDKHILTQGGHIIKKK"
gene complement(257992..259401)
/gene="SHM2"
/locus_tag="YLR058C"
/gene_synonym="SHMT2"
/db_xref="GeneID:850747"
mRNA complement(257992..259401)
/gene="SHM2"
/locus_tag="YLR058C"
/gene_synonym="SHMT2"
/product="glycine hydroxymethyltransferase SHM2"
/transcript_id="NM_001181945.1"
/db_xref="GI:296146596"
/db_xref="GeneID:850747"
CDS complement(257992..259401)
/gene="SHM2"
/locus_tag="YLR058C"
/gene_synonym="SHMT2"
/EC_number="2.1.2.1"
/note="Cytosolic serine hydroxymethyltransferase, converts
serine to glycine plus 5,10 methylenetetrahydrofolate;
major isoform involved in generating precursors for
purine, pyrimidine, amino acid, and lipid biosynthesis"
/codon_start=1
/product="glycine hydroxymethyltransferase SHM2"
/protein_id="NP_013159.1"
/db_xref="GI:6323087"
/db_xref="SGD:S000004048"
/db_xref="GeneID:850747"
/translation="MPYTLSDAHHKLITSHLVDTDPEVDSIIKDEIERQKHSIDLIAS
ENFTSTSVFDALGTPLSNKYSEGYPGARYYGGNEHIDRMEILCQQRALKAFHVTPDKW
GVNVQTLSGSPANLQVYQAIMKPHERLMGLYLPDGGHLSHGYATENRKISAVSTYFES
FPYRVNPETGIIDYDTLEKNAILYRPKVLVAGTSAYCRLIDYKRMREIADKCGAYLMV
DMAHISGLIAAGVIPSPFEYADIVTTTTHKSLRGPRGAMIFFRRGVRSINPKTGKEVL
YDLENPINFSVFPGHQGGPHNHTIAALATALKQAATPEFKEYQTQVLKNAKALESEFK
NLGYRLVSNGTDSHMVLVSLREKGVDGARVEYICEKINIALNKNSIPGDKSALVPGGV
RIGAPAMTTRGMGEEDFHRIVQYINKAVEFAQQVQQSLPKDACRLKDFKAKVDEGSDV
LNTWKKEIYDWAGEYPLAV"
gene complement(259738..260547)
/gene="REX2"
/locus_tag="YLR059C"
/gene_synonym="YNT20"
/db_xref="GeneID:850748"
mRNA complement(259738..260547)
/gene="REX2"
/locus_tag="YLR059C"
/gene_synonym="YNT20"
/product="Rex2p"
/transcript_id="NM_001181946.1"
/db_xref="GI:296146597"
/db_xref="GeneID:850748"
CDS complement(259738..260547)
/gene="REX2"
/locus_tag="YLR059C"
/gene_synonym="YNT20"
/EC_number="3.1.-.-"
/note="3'-5' RNA exonuclease; involved in 3'-end
processing of U4 and U5 snRNAs, 5S and 5.8S rRNAs, and
RNase P and RNase MRP RNA; localized to mitochondria and
null suppresses escape of mtDNA to nucleus in yme1 yme2
mutants; RNase D exonuclease"
/codon_start=1
/product="Rex2p"
/protein_id="NP_013160.1"
/db_xref="GI:6323088"
/db_xref="SGD:S000004049"
/db_xref="GeneID:850748"
/translation="MKWLLFPARIVARTRPNLFSLYRRSVSQYLRPRTIQNLQSMAQT
PELKTKLFKPLVWIDCEMTGLDHVNDRIIEICCIITDGHLAPVKAADGQGDSHYESVI
HYGPEVMNKMNEWCIEHHGNSGLTAKVLASEKTLAQVEDELLEYIQRYIPDKNVGVLA
GNSVHMDRLFMVREFPKVIDHLFYRIVDVSSIMEVARRHNPALQARNPKKEAAHTAYS
DIKESIAQLQWYMDNYLKPPQETESVESIGSEQPESPSSSTSSLKRQRTDF"
gene 260979..262766
/gene="FRS1"
/locus_tag="YLR060W"
/db_xref="GeneID:850749"
mRNA 260979..262766
/gene="FRS1"
/locus_tag="YLR060W"
/product="phenylalanine--tRNA ligase subunit beta"
/transcript_id="NM_001181947.1"
/db_xref="GI:296146598"
/db_xref="GeneID:850749"
CDS 260979..262766
/gene="FRS1"
/locus_tag="YLR060W"
/EC_number="6.1.1.20"
/note="Beta subunit of cytoplasmic phenylalanyl-tRNA
synthetase, forms a tetramer with Frs2p to generate active
enzyme; able to hydrolyze mis-aminoacylated tRNA-Phe,
which could contribute to translational quality control"
/codon_start=1
/product="phenylalanine--tRNA ligase subunit beta"
/protein_id="NP_013161.1"
/db_xref="GI:6323089"
/db_xref="SGD:S000004050"
/db_xref="GeneID:850749"
/translation="MPTVSVNKQQLFDLLGKNYTSQEFDELCFEFGMEMDEDTTEEAL
KTGEEPELKLDISANRYDLLCIEGISQSLNEYLERKERPDYKLSKPTTKLIIDKSTEQ
IRPFATAAVLRNIKLNEKSYASFIALQDKLHANLCRNRSLVAMGTHDLDSIEGPFHYR
ALPPKDIKFVPLNQTQEFTGDKLIEFYKSPEQKNNIGRYVHIIEDSPVFPVIMDSKDR
VCSLPPLINSEHSKISVNTRNILIDITATDKTKAEIVLNILTTMFSRYCDEPFTVEPV
EIVSEHNGQSRLAPNFNDRIMDVSIKYINSCLGLDQSADEIAHCLKKMSLHAVQSKED
KDILHVDIPVTRPDILHACDIMEDAAVGYGFNNLPKGEKLSNANFIAKPLPINKVSDI
FRVASSQATWVEVLPLTLCSHDENFKFLRQSDNGDLAVKLANPKTLEYQVVRTTLLPG
ILKTVKENRKHSLPIKVFETGDVVFKDDKLERKAYNERHWAAIYVGKNSGFEIIQGLL
GKIMQTFRTEWIADYGAAASGRGYWIEEDDSVKTYFPGRGAKVMFRSKEGAEPKQIGH
LGVLHPEVMMNFDVPFAASFVEVNAEVFL"
gene 263194..263948
/gene="RPL22A"
/locus_tag="YLR061W"
/db_xref="GeneID:850750"
mRNA join(263194..263205,263595..263948)
/gene="RPL22A"
/locus_tag="YLR061W"
/product="ribosomal 60S subunit protein L22A"
/transcript_id="NM_001181948.1"
/db_xref="GI:296146599"
/db_xref="GeneID:850750"
CDS join(263194..263205,263595..263948)
/gene="RPL22A"
/locus_tag="YLR061W"
/note="Ribosomal 60S subunit protein L22A; required for
the oxidative stress response in yeast; homologous to
mammalian ribosomal protein L22, no bacterial homolog;
RPL22A has a paralog, RPL22B, that arose from the whole
genome duplication"
/codon_start=1
/product="ribosomal 60S subunit protein L22A"
/protein_id="NP_013162.1"
/db_xref="GI:6323090"
/db_xref="SGD:S000004051"
/db_xref="GeneID:850750"
/translation="MAPNTSRKQKIAKTFTVDVSSPTENGVFDPASYAKYLIDHIKVE
GAVGNLGNAVTVTEDGTVVTVVSTAKFSGKYLKYLTKKYLKKNQLRDWIRFVSTKTNE
YRLAFYQVTPEEDEEEDEE"
gene 264157..265254
/locus_tag="YLR063W"
/db_xref="GeneID:850752"
mRNA 264157..265254
/locus_tag="YLR063W"
/product="hypothetical protein"
/transcript_id="NM_001181950.1"
/db_xref="GI:296146600"
/db_xref="GeneID:850752"
CDS 264157..265254
/locus_tag="YLR063W"
/note="Putative S-adenosylmethionine-dependent
methyltransferase; green fluorescent protein (GFP)-fusion
protein localizes to the cytoplasm; YLR063W is not an
essential gene"
/codon_start=1
/product="hypothetical protein"
/protein_id="NP_013164.1"
/db_xref="GI:6323092"
/db_xref="SGD:S000004053"
/db_xref="GeneID:850752"
/translation="MLLMRRFAFLTSSVYFKYIPIYSQYHYSSQFPINMNPKKVAQLP
VHNKSTLPPQEIIDLFKITFLEELYPKDQDNEKSPLTEQIQAVKSDLYNRDYNAAFNN
DSKRIAYCCRWSPSRATSYASVFAHFPELLKIIRCEIDDKDSNVLCIGGGAGGELVAL
ASIFTLSRDFSSKFASALKIDNEVNKKPRNLNIQLVDIADWSTVVEKLTATIKSKWLY
GDSEAESFNVNFTHKDCLQMTEPQDIKIYQGLDLITLLFTTNELFTQKKVESIKFLQR
LNENCAPGCHLLILESAGSYSHITINNKKFPIQFLIDTILVGNRKDKGTTGPWSLVSE
NDSIWYRMDPKLDYSIPLENMRFFYRLYVKN"
gene 265456..266277
/gene="PER33"
/locus_tag="YLR064W"
/db_xref="GeneID:850753"
mRNA 265456..266277
/gene="PER33"
/locus_tag="YLR064W"
/product="Per33p"
/transcript_id="NM_001181951.1"
/db_xref="GI:296146601"
/db_xref="GeneID:850753"
CDS 265456..266277
/gene="PER33"
/locus_tag="YLR064W"
/note="Protein that localizes to the endoplasmic
reticulum; also associates with the nuclear pore complex;
deletion extends chronological lifespan; highly conserved
across species, orthologous to human TMEM33 and paralogous
to Pom33p; protein abundance increases in response to DNA
replication stress"
/codon_start=1
/product="Per33p"
/protein_id="NP_013165.1"
/db_xref="GI:6323093"
/db_xref="SGD:S000004054"
/db_xref="GeneID:850753"
/translation="MTVPRNRPMAPFGTIIKSRIKQPQFYWFIGHFLTIFNFIQFHLS
ITSKQNQLSCYRRSLFYISVTYAIVLYQFFKSDQLKFNFTLLRQEMKKLDNLQYFAML
FILFLLSQFNIIISGSLYSPVIFSIFHFLNYFKENLLPFLPLIPLNLKNLLNSKITVF
IQNYNGFFLQMAQVFEIICGLRVGLFLVPFNFFLLLVRRANVSFEVVGTMLAGLTYVW
FFKLRYLQSESMRQIFKQYVLRLDAYVSRTLPPYCSRLWNGYKNFVMTVFWKIPV"
gene complement(266373..266918)
/gene="ENV10"
/locus_tag="YLR065C"
/db_xref="GeneID:850754"
mRNA complement(266373..266918)
/gene="ENV10"
/locus_tag="YLR065C"
/product="Env10p"
/transcript_id="NM_001181952.1"
/db_xref="GI:296146602"
/db_xref="GeneID:850754"
CDS complement(266373..266918)
/gene="ENV10"
/locus_tag="YLR065C"
/note="Protein proposed to be involved in vacuolar
functions; mutant shows defect in CPY processing; YLR065C
is not an essential gene"
/codon_start=1
/product="Env10p"
/protein_id="NP_013166.1"
/db_xref="GI:6323094"
/db_xref="SGD:S000004055"
/db_xref="GeneID:850754"
/translation="MAGKAGRKQASSNAKIIQGLYKQVSLFLGMAIVRLFISRKVTIG
QWIKLVALNVPMFVALYIIVLSGKPKYDGNRVVKQGIDLNDNTNLISYFFDLIYLSLF
GNIGIIAFRTFKFWWCLLLCPIYAGYKLYGLKNMFMPGAQQTQADNRSKNANEGQSKS
KRQMKRERRGETDSKIKYKYR"
gene 267169..267723
/gene="SPC3"
/locus_tag="YLR066W"
/db_xref="GeneID:850755"
mRNA 267169..267723
/gene="SPC3"
/locus_tag="YLR066W"
/product="Spc3p"
/transcript_id="NM_001181953.1"
/db_xref="GI:296146603"
/db_xref="GeneID:850755"
CDS 267169..267723
/gene="SPC3"
/locus_tag="YLR066W"
/note="Subunit of signal peptidase complex (Spc1p, Spc2p,
Spc3p, Sec11p), which catalyzes cleavage of N-terminal
signal sequences of proteins targeted to the secretory
pathway; homologous to mammalian SPC22/23"
/codon_start=1
/product="Spc3p"
/protein_id="NP_013167.1"
/db_xref="GI:6323095"
/db_xref="SGD:S000004056"
/db_xref="GeneID:850755"
/translation="MFSFVQRFQNVSNQAFSMGIVMVVFIMASSYYQLINNNAFSVPS
NIDNVKTLINVRTSRYFGSQRGKAKENMKIKFDLNTDLTPLFNWNTKQVFVYLTAEYN
STEKITSEVTFWDKIIKSKDDAVIDVNDLRSKYSIWDIEDGKFEGKDLVFKLHWNVQP
WVGLLTYGETVGNYTLTVENKNKV"
gene complement(267813..270710)
/gene="PET309"
/locus_tag="YLR067C"
/db_xref="GeneID:850756"
mRNA complement(267813..270710)
/gene="PET309"
/locus_tag="YLR067C"
/product="Pet309p"
/transcript_id="NM_001181954.1"
/db_xref="GI:296146604"
/db_xref="GeneID:850756"
CDS complement(267813..270710)
/gene="PET309"
/locus_tag="YLR067C"
/note="Specific translational activator for the COX1 mRNA,
also influences stability of intron-containing COX1
primary transcripts; localizes to the mitochondrial inner
membrane; contains seven pentatricopeptide repeats (PPRs)"
/codon_start=1
/product="Pet309p"
/protein_id="NP_013168.1"
/db_xref="GI:6323096"
/db_xref="SGD:S000004057"
/db_xref="GeneID:850756"
/translation="MKRCAPAVLRNYNYKKGIWSTGVPDHIRKLLRDKSTSPLCSQDE
RNLVSYFMARGSVPLKSVGSGLTKKATTSITSNSATTTFERQYLIKYLYRHQAYGNVI
KIAQKFLYTTIGSQRLLKQDASLPELKKFLLSLLILQRGIQLDQAISDIIQRFLLTQK
TMVIDLINSIFSRMVIMNMHEEAVYKWVKWMKLVNGHCEFTNYMENKIVLRNFLSFMR
QSNVRPDYLSYLKAIQLTQGPAIASQFATTLLFLLTYIRKFSSAEAVWNYKCEHNLPI
VSSDLTCILKTYCHMQKFNLVSSTYWKYPDAQHDQNQFDYLLVAHSRLHNWDALQQQF
NALFGIGKLPSIQHYGILMYTMARIGELDSVNKLYTQLLRRGMIPTYAVLQSLLYAHY
KVGDFAACFSHFELFKKYDITPSTATHTIMLKVYRGLNDLDGAFRILKRLSEDPSVEI
TEGHFALLIQMCCKTTNHLIAQELFNLMTEHYNIQHTGKSISALMDVYIESNRPTEAI
ALFEKHSKNLSWRDGLISVYNKAIKAYIGLRNANKCEELFDKITTSKLAVNSEFYKMM
IKFLVTLNEDCETALSIIDQLIKHSVIKVDATHFEIIMEAYDKEGYRDGIINLYKTMS
QNKVPANSKILYYILKAVAKKSLQNNEEIKETINMVEDIMENAANGTLDVTYNKLHPS
VMAWPMRMIVKHDSPQRALELYNRYNELFFKKHDWISNNNKFVMMRSLLVLLAQIEQW
KDFETLFAKYMDRIENIENLPSSTTPNIKLRSIFSGLFPYKVSQLIAMNKIDELPLLW
KKLREKGFILDNISWNSAVEALFKDPRTLSYGMKIVDDTLIHGYNLIHKFRLLTKLSE
DKTQSSDKSWPTLKMKEKEPNKFQPRLYLKSDTYNSIMRQLDTYLDGIDDLKTLEDQV
RDFISNYKYFMKDYLLMPRSKINKWEQIEMRHLSYFKELRKSKRVLPVSKF"
gene 271008..271463
/gene="FYV7"
/locus_tag="YLR068W"
/db_xref="GeneID:850757"
mRNA 271008..271463
/gene="FYV7"
/locus_tag="YLR068W"
/product="Fyv7p"
/transcript_id="NM_001181955.1"
/db_xref="GI:296146605"
/db_xref="GeneID:850757"
CDS 271008..271463
/gene="FYV7"
/locus_tag="YLR068W"
/note="Essential protein required for maturation of 18S
rRNA; required for survival upon exposure to K1 killer
toxin"
/codon_start=1
/product="Fyv7p"
/protein_id="NP_013169.1"
/db_xref="GI:6323097"
/db_xref="SGD:S000004058"
/db_xref="GeneID:850757"
/translation="MGTAKQNQNRKKFTREYKVKEIQRSITKKTRLRKEYLKALKDEG
YAVPEKEPKTVAKESVRKIKEARAIEGKKKLDEKKEIKKQRKRMQKDELNKQRNEQLE
RIRVSKEKFQRREDRKKKLTQRTRTGQPLMGPKIEDLLDKIKTDDTYTS"
gene complement(271630..273915)
/gene="MEF1"
/locus_tag="YLR069C"
/db_xref="GeneID:850758"
mRNA complement(271630..273915)
/gene="MEF1"
/locus_tag="YLR069C"
/product="Mef1p"
/transcript_id="NM_001181956.1"
/db_xref="GI:296146606"
/db_xref="GeneID:850758"
CDS complement(271630..273915)
/gene="MEF1"
/locus_tag="YLR069C"
/note="Mitochondrial elongation factor involved in
translational elongation"
/codon_start=1
/product="Mef1p"
/protein_id="NP_013170.1"
/db_xref="GI:6323098"
/db_xref="SGD:S000004059"
/db_xref="GeneID:850758"
/translation="MSVQKMMWVPRKMVGGRIPFFTCSKVFSGFSRRSFHESPLARST
YEEEKVLVDEIKQKLTPDDIGRCNKLRNIGISAHIDSGKTTFTERVLYYTKRIKAIHE
VRGRDNVGAKMDSMDLEREKGITIQSAATYCSWDKEGKNYHFNLIDTPGHIDFTIEVE
RALRVLDGAVLVVCAVSGVQSQTVTVDRQMRRYNVPRVTFINKMDRMGSDPFRAIEQL
NSKLKIPAAAVQIPIGSESSLSGVVDLINRVAIYNKGDNGEIIEKGPVPENLKPLMEE
KRQLLIETLADVDDEMAEMFLEEKEPTTQQIKDAIRRSTIARSFTPVLMGSALANTGI
QPVLDAIVDYLPNPSEVLNTALDVSNNEAKVNLVPAVQQPFVGLAFKLEEGKYGQLTY
VRVYQGRLRKGNYITNVKTGKKVKVARLVRMHSSEMEDVDEVGSGEICATFGIDCASG
DTFTDGSVQYSMSSMYVPDAVVSLSITPNSKDASNFSKALNRFQKEDPTFRVKFDPES
KETIISGMGELHLEIYVERMRREYNVDCVTGKPQVSYRESITIPADFDYTHKKQSGGA
GQYGRVIGTLSPVDDITKGNIFETAIVGGRIPDKYLAACGKGFEEVCEKGPLIGHRVL
DVKMLINDGAIHAVDSNELSFKTATMSAFRDAFLRAQPVIMEPIMNVSVTSPNEFQGN
VIGLLNKLQAVIQDTENGHDEFTLKAECALSTMFGFATSLRASTQGKGEFSLEFSHYA
PTAPHVQKELISEFQKKQAKK"
gene complement(274141..275211)
/gene="XYL2"
/locus_tag="YLR070C"
/db_xref="GeneID:850759"
mRNA complement(274141..275211)
/gene="XYL2"
/locus_tag="YLR070C"
/product="D-xylulose reductase XYL2"
/transcript_id="NM_001181957.1"
/db_xref="GI:296146607"
/db_xref="GeneID:850759"
CDS complement(274141..275211)
/gene="XYL2"
/locus_tag="YLR070C"
/EC_number="1.1.1.9"
/note="Xylitol dehydrogenase, converts xylitol to
D-xylulose; expression induced by xylose, even though this
pentose sugar is not well utilized by S. cerevisiae; null
mutant has cell wall defect"
/codon_start=1
/product="D-xylulose reductase XYL2"
/protein_id="NP_013171.1"
/db_xref="GI:6323099"
/db_xref="SGD:S000004060"
/db_xref="GeneID:850759"
/translation="MTDLTTQEAIVLERPGKITLTNVSIPKISDPNEVIIQIKATGIC
GSDIHYYTHGRIANYVVESPMVLGHESSGIVALIGENVKTLKVGDRVALEPGIPDRFS
PEMKEGRYNLDPNLKFAATPPFDGTLTKYYKTMKDFVYKLPDDVSFEEGALIEPLSVA
IHANKLAKIKFGARCVVFGAGPIGLLAGKVASVFGAADVVFVDLLENKLETARQFGAT
HIVNSGDLPHGVTVDSVIKKAIGKKGADVVFECSGAEPCVRAGIEVCKAGGTIVQVGM
GQEEIQFPISIIPTKELTFQGCFRYCQGDYSDSIELVSSRKLSLKPFITHRYSFKDAV
EAFEETSHHPLNNIKTIIEGPE"
gene complement(275378..278626)
/gene="RGR1"
/locus_tag="YLR071C"
/gene_synonym="MED14"
/db_xref="GeneID:850760"
mRNA complement(275378..278626)
/gene="RGR1"
/locus_tag="YLR071C"
/gene_synonym="MED14"
/product="Rgr1p"
/transcript_id="NM_001181958.1"
/db_xref="GI:296146608"
/db_xref="GeneID:850760"
CDS complement(275378..278626)
/gene="RGR1"
/locus_tag="YLR071C"
/gene_synonym="MED14"
/note="Subunit of the RNA polymerase II mediator complex;
associates with core polymerase subunits to form the RNA
polymerase II holoenzyme; required for glucose repression,
HO repression, RME1 repression and sporulation"
/codon_start=1
/product="Rgr1p"
/protein_id="NP_013172.1"
/db_xref="GI:6323100"
/db_xref="SGD:S000004061"
/db_xref="GeneID:850760"
/translation="MTTTIGSPQMLANEERLSNEMHALKNRSEQNGQEQQGPVKNTQL
HGPSATDPETTATQKESLEMVPKDTSAATMTSAPPPALPHVEINQVSLALVIRNLTVF
TMKELAQYMKTNVHTQANEPNSAKKIRFLQLIIFLRTQFLKLYVLVKWTRTIKQNNFH
VLIDLLNWFRTTNMNVNNCIWALKSSLNSMTNAKLPNVDLVTALEVLSLGRPNLPTHN
FKLSGVSNSMDMVDGMAKVPIGLILQRLKDLNLTVSIKIALMNIPKPLNSYHIKNGRI
YFTVPNEFEIQLSTVNRQSPLFFVDLKLLFNTEAEQTVSAVTEATSTNGDSENNEENS
SSNGNNLPLNKPRLEKLINEILLKSNDPLLSLYNFLHKYVLTLQLYMVHREFLKLANG
GKFSKSNLIHNYDSKKSTITVRYWLNGKMDSKGKITIGIQRTTESLILKWDNQSASRA
KNMPVIYNNIVSNIEGILDEIMFNHARIIRSELLARDIFQEDEENSDVLLFQLPTTCV
SMAPIQLKIDLLSGQFYFRNPTPLLSNYASKINRAEGPEELARILQQLKLDKIIHVLT
TMFENTGWSCSRIIKIDKPIRTQVNTGGESVVKKEDNKYAIAGNSTTNSDVSLLLQRD
LFIRLPHWPLNWYLILSIISSKTSCVVEKRIGKIVSQRGKWNLKYLDNSNVMTVKLES
ITYQKIMILQRTILNRIINHMLIDSLNQLEIRNKICSSEMINEQKLPQYIIQGSNTND
NISIITLELESFLEGSKALNSILESSMFLRIDYSNSQIRLYAKFKRNTMMIQCQIDKL
YIHFVQEEPLAFYLEESFTNLGIIVQYLTKFRQKLMQLVVLTDVVERLHKNFESENFK
IIALQPNEISFKYLSNNDEDDKDCTIKISTNDDSIKNLTVQLSPSNPQHIIQPFLDNS
KMDYHFIFSYLQFTSSLFKALKVILNERGGKFHESGSQYSTMVNIGLHNLNEYQIVYY
NPQAGTKITICIELKTVLHNGRDKIQFHIHFADVAHITTKSPAYPMMHQVRNQVFMLD
TKRLGTPESVKPANASHAIRLGNGVACDPSEIEPILMEIHNILKVDSNSSSS"
gene 278862..280943
/locus_tag="YLR072W"
/db_xref="GeneID:850761"
mRNA 278862..280943
/locus_tag="YLR072W"
/product="hypothetical protein"
/transcript_id="NM_001181959.1"
/db_xref="GI:296146609"
/db_xref="GeneID:850761"
CDS 278862..280943
/locus_tag="YLR072W"
/note="hypothetical protein; green fluorescent protein
(GFP)-fusion protein localizes to the cytoplasm in a
punctate pattern; YLR072W is not an esssential gene"
/codon_start=1
/product="hypothetical protein"
/protein_id="NP_013173.1"
/db_xref="GI:6323101"
/db_xref="SGD:S000004062"
/db_xref="GeneID:850761"
/translation="MWGDSMRELGDAMDNELNAVKPVVEEGGMDGARKFIKGKSFQKS
STEHMLISPGRDGSVPLNGLKSSPADPHLSDVNSILDNHRGGGETALTSVNNIIMATS
TNGDSDGVDGDAKRPSISNCSSRSSFFDTVLSTFSLKSNSQDTVTNEVKNIEVQFASE
EANKKFRQMFKPLAPNTRLITDYFCYFHREFPYQGRIYLSNTHLCFNSTVLNWMAKLQ
IPLNEIKYLDKVTTNSSAISVETVTNRYTFSGFIARDEVFQLITRVWSKENLTNINDV
LEVDERVSKKKGISSTPSSIFNNVSTNAYNDFISTTTTEPTSRASYMSENDMLIEEAI
RSVDDYMGTPRASPSSSSSSSSSSSSLGSSTTYYCRPVYRLKPNAPFQYEGPFHVQET
MDFPYKPEANNEYVLLERQFSVPPGLLFIMMFNEDNPVFELSFLKTQDSSNISHIGTF
EKVNKDGQHYREFQYTKQLHFPVGPKSTNCEVAEILLHCDWERYINVLSITRTPNVPS
GTSFSTRTRYMFRWDDQGQGCILKISFWVDWNASSWIKPMVESNCKNGQISATKDLVK
LVEEFVEKYVELSKEKADTLKPLPSVTSFGSPRKVAAPELTMVQPESKPEAEAEISEI
GSDRWRFNWVNIIILVLLVLNLLYLMKLNKKMDKLTNLMTHKDEVVAHATLLDIPAKV
QWSRPRRGDVL"
gene complement(281019..281621)
/gene="RFU1"
/locus_tag="YLR073C"
/db_xref="GeneID:850762"
mRNA complement(281019..281621)
/gene="RFU1"
/locus_tag="YLR073C"
/product="Rfu1p"
/transcript_id="NM_001181960.1"
/db_xref="GI:296146610"
/db_xref="GeneID:850762"
CDS complement(281019..281621)
/gene="RFU1"
/locus_tag="YLR073C"
/note="Protein that inhibits Doa4p deubiquitinating
activity; contributes to ubiquitin homeostasis by
regulating the conversion of free ubiquitin chains to
ubiquitin monomers by Doa4p; GFP-fusion protein localizes
to endosomes"
/codon_start=1
/product="Rfu1p"
/protein_id="NP_013174.1"
/db_xref="GI:6323102"
/db_xref="SGD:S000004063"
/db_xref="GeneID:850762"
/translation="MKSSKQLVQDAKDYRFNPAIPLRIYLKTCIGILEKAQCAFQAND
LSLSFIYYFRYVDLLTNKLSRHPELLRMDASSSSSSSYIHKREYLQLIKLEVPAVCKI
IESLRTQIDSQYSKLQTSLANNIAKPNINANTTPVQVEQQPLPKKSFDEYSFNQSISF
FQKISNAQLNTGASSQSQATARDEAYRLNYPELPRLTFST"
gene complement(281956..282456)
/gene="BUD20"
/locus_tag="YLR074C"
/db_xref="GeneID:850763"
mRNA complement(281956..282456)
/gene="BUD20"
/locus_tag="YLR074C"
/product="Bud20p"
/transcript_id="NM_001181961.1"
/db_xref="GI:296146611"
/db_xref="GeneID:850763"
CDS complement(281956..282456)
/gene="BUD20"
/locus_tag="YLR074C"
/note="Protein involved in bud-site selection; diploid
mutants display a random budding pattern instead of the
wild-type bipolar pattern"
/codon_start=1
/product="Bud20p"
/protein_id="NP_013175.1"
/db_xref="GI:6323103"
/db_xref="SGD:S000004064"
/db_xref="GeneID:850763"
/translation="MGRYSVKRYKTKRRTRDLDLIYNDLSTKESVQKLLNQPLDETKP
GLGQHYCIHCAKYMETAIALKTHLKGKVHKRRVKELRGVPYTQEVSDAAAGYNLNKFL
NRVQEITQSVGPEKESNEALLKEHLDSTLANVKTTEPTLPWAAADAEANTAAVTEAES
TASAST"
gene 282927..283592
/gene="RPL10"
/locus_tag="YLR075W"
/gene_synonym="GRC5; QSR1"
/db_xref="GeneID:850764"
mRNA 282927..283592
/gene="RPL10"
/locus_tag="YLR075W"
/gene_synonym="GRC5; QSR1"
/product="ribosomal 60S subunit protein L10"
/transcript_id="NM_001181962.1"
/db_xref="GI:296146612"
/db_xref="GeneID:850764"
CDS 282927..283592
/gene="RPL10"
/locus_tag="YLR075W"
/gene_synonym="GRC5; QSR1"
/note="Ribosomal 60S subunit protein L10; responsible for
joining the 40S and 60S subunits; regulates translation
initiation; similar to members of the QM gene family;
homologous to mammalian ribosomal protein L10 and
bacterial L16; protein abundance increases in response to
DNA replication stress"
/codon_start=1
/product="ribosomal 60S subunit protein L10"
/protein_id="NP_013176.1"
/db_xref="GI:6323104"
/db_xref="SGD:S000004065"
/db_xref="GeneID:850764"
/translation="MARRPARCYRYQKNKPYPKSRYNRAVPDSKIRIYDLGKKKATVD
EFPLCVHLVSNELEQLSSEALEAARICANKYMTTVSGRDAFHLRVRVHPFHVLRINKM
LSCAGADRLQQGMRGAWGKPHGLAARVDIGQIIFSVRTKDSNKDVVVEGLRRARYKFP
GQQKIILSKKWGFTNLDRPEYLKKREAGEVKDDGAFVKFLSKKGSLENNIREFPEYFA
AQA"
gene 283872..285623
/gene="FMP25"
/locus_tag="YLR077W"
/gene_synonym="BCA1"
/db_xref="GeneID:850766"
mRNA 283872..285623
/gene="FMP25"
/locus_tag="YLR077W"
/gene_synonym="BCA1"
/product="Fmp25p"
/transcript_id="NM_001181964.1"
/db_xref="GI:296146613"
/db_xref="GeneID:850766"
CDS 283872..285623
/gene="FMP25"
/locus_tag="YLR077W"
/gene_synonym="BCA1"
/note="Mitochondrial inner membrane protein required for
an early step in assembly of respiratory complex III
(cytochrome bc1 complex); mRNA is targeted to
mitochondria"
/codon_start=1
/product="Fmp25p"
/protein_id="NP_013178.1"
/db_xref="GI:6323106"
/db_xref="SGD:S000004067"
/db_xref="GeneID:850766"
/translation="MSFRLFTRTSQRLPRLNWVSPIRRYAKQPQYDEAELFAENINHG
AYKAKKRPSDEHFQWPEKSPDQITKESELQWERMAKLSAVGQGILILVVVGGLGTAYL
RWPELKSWWLIKMNGGRINATQEQSGQDSLEKLIRQKAKNLLREIPQVPAFQLGIDHP
GVYIWGRCHSKDSLFPVRVPNLDGRKFRDILLAPSDDFNTNFAIDEKGDLISWDDLGQ
TKTILPDQDLTSMKYSSHFLYALNKKGEILVIPIRTPDLIASQVSSRRSKLLPWKTKL
RYDWKLQTNQIFNGKEGEKRVVQFDAGSHHLVLLSNLGKAYCCATGNDQKQAQVSKGQ
FGIPTFSQFDEFPPNNQLFEIELLNKFKHEGEDVVRKREIKKIACGSYHTLAIDKTGE
IYAFGWNRFGQLALPISYNLEYVSFPRSVTHAFKPHFPGMTNWKCVDIHCDDETSFVT
IRKPGSTSDHHYFAFGNGLFGELGNNTFKNSQCDPIKIKSDDKKLTNWSCGSHCVFTE
TEQENEVIAWGNNDHGQLGIGKKTMKCAKPMNIPEVLKPGQDTTDLDSIYNSKLHLKK
EQRVVTNGNKSCLYWRV"
gene complement(285736..286559)
/gene="BOS1"
/locus_tag="YLR078C"
/gene_synonym="SEC32"
/db_xref="GeneID:850767"
mRNA complement(join(285736..286467,286557..286559))
/gene="BOS1"
/locus_tag="YLR078C"
/gene_synonym="SEC32"
/product="Bos1p"
/transcript_id="NM_001181965.1"
/db_xref="GI:296146614"
/db_xref="GeneID:850767"
CDS complement(join(285736..286467,286557..286559))
/gene="BOS1"
/locus_tag="YLR078C"
/gene_synonym="SEC32"
/note="v-SNARE (vesicle specific SNAP receptor), localized
to the endoplasmic reticulum membrane and necessary for
vesicular transport from the ER to the Golgi"
/codon_start=1
/product="Bos1p"
/protein_id="NP_013179.1"
/db_xref="GI:6323107"
/db_xref="SGD:S000004068"
/db_xref="GeneID:850767"
/translation="MNALYNHAVKQKNQLQQELARFEKNSVTAPISLQGSISATLVSL
EKTVKQYAEHLNRYKEDTNAEEIDPKFANRLATLTQDLHDFTAKFKDLKQSYNENNSR
TQLFGSGASHVMDSDNPFSTSETIMNKRNVGGASANGKEGSSNGGGLPLYQGLQKEQS
VFERGNAQLDYILEMGQQSFENIVEQNKILSKVQDRMSNGLRTLGVSEQTITSINKRV
FKDKLVFWIALILLIIGIYYVLKWLR"
gene 286820..287674
/gene="SIC1"
/locus_tag="YLR079W"
/gene_synonym="SDB25"
/db_xref="GeneID:850768"
mRNA 286820..287674
/gene="SIC1"
/locus_tag="YLR079W"
/gene_synonym="SDB25"
/product="Sic1p"
/transcript_id="NM_001181966.1"
/db_xref="GI:296146615"
/db_xref="GeneID:850768"
CDS 286820..287674
/gene="SIC1"
/locus_tag="YLR079W"
/gene_synonym="SDB25"
/note="Cyclin-dependent kinase inhibitor (CKI); inhibitor
of Cdc28-Clb kinase complexes that controls G1/S phase
transition, preventing premature S phase and ensuring
genomic integrity; phosphorylation targets Sic1p for
SCF(CDC4)-dependent turnover; functional homolog of
mammalian Kip1"
/codon_start=1
/product="Sic1p"
/protein_id="NP_013180.1"
/db_xref="GI:6323108"
/db_xref="SGD:S000004069"
/db_xref="GeneID:850768"
/translation="MTPSTPPRSRGTRYLAQPSGNTSSSALMQGQKTPQKPSQNLVPV
TPSTTKSFKNAPLLAPPNSNMGMTSPFNGLTSPQRSPFPKSSVKRTLFQFESHDNGTV
REEQEPLGRVNRILFPTQQNVDIDAAEEEEEGEVLLPPSRPTSARQLHLSLERDEFDQ
THRKKIIKDVPGTPSDKVITFELAKNWNNNSPKNDARSQESEDEEDIIINPVRVGKNP
FASDELVTQEIRNERKRAMLRENPDIEDVITYVNKKGEVVEKRRLTDEEKRRFKPKAL
FQSRDQEH"
gene 287916..289250
/gene="EMP46"
/locus_tag="YLR080W"
/db_xref="GeneID:850769"
mRNA 287916..289250
/gene="EMP46"
/locus_tag="YLR080W"
/product="Emp46p"
/transcript_id="NM_001181967.1"
/db_xref="GI:296146616"
/db_xref="GeneID:850769"
CDS 287916..289250
/gene="EMP46"
/locus_tag="YLR080W"
/note="Integral membrane component of endoplasmic
reticulum-derived COPII-coated vesicles, which function in
ER to Golgi transport"
/codon_start=1
/product="Emp46p"
/protein_id="NP_013181.1"
/db_xref="GI:6323109"
/db_xref="SGD:S000004070"
/db_xref="GeneID:850769"
/translation="MTTRKTASSLQLLGKITGTKAGTKQKKMNFINGLIWLYMCVWMV
HGKVTQKDELKWNKGYSLPNLLEVTDQQKELSQWTLGDKVKLEEGRFVLTPGKNTKGS
LWLKPEYSIKDAMTIEWTFRSFGFRGSTKGGLAFWLKQGNEGDSTELFGGSSKKFNGL
MILLRLDDKLGESVTAYLNDGTKDLDIESSPYFASCLFQYQDSMVPSTLRLTYNPLDN
HLLKLQMDNRVCFQTRKVKFMGSSPFRIGTSAINDASKESFEILKMKLYDGVIEDSLI
PNVNPMGQPRVVTKVINSQTGEESFREKMPFSDKEESITSNELFEKMNKLEGKIMAND
IDPLLRKMNKIVENERELIQRLRPLLDLKKTAISDDSFQDFLSMNANLDRLIKEQEKI
RQDAKLYGKQTKGHDEIFSKISVWLALLIFIMITLAYYMFRINQDIKKVKLL"
rep_origin 289220..289468
/note="ARS1212;
Late-firing chromosomal replication origin"
/db_xref="SGD:S000118472"
gene 290212..291936
/gene="GAL2"
/locus_tag="YLR081W"
/db_xref="GeneID:850770"
mRNA 290212..291936
/gene="GAL2"
/locus_tag="YLR081W"
/product="Gal2p"
/transcript_id="NM_001181968.1"
/db_xref="GI:296146617"
/db_xref="GeneID:850770"
CDS 290212..291936
/gene="GAL2"
/locus_tag="YLR081W"
/note="Galactose permease, required for utilization of
galactose; also able to transport glucose"
/codon_start=1
/product="Gal2p"
/protein_id="NP_013182.1"
/db_xref="GI:6323110"
/db_xref="SGD:S000004071"
/db_xref="GeneID:850770"
/translation="MAVEENNMPVVSQQPQAGEDVISSLSKDSHLSAQSQKYSNDELK
AGESGSEGSQSVPIEIPKKPMSEYVTVSLLCLCVAFGGFMFGWDTGTISGFVVQTDFL
RRFGMKHKDGTHYLSNVRTGLIVAIFNIGCAFGGIILSKGGDMYGRKKGLSIVVSVYI
VGIIIQIASINKWYQYFIGRIISGLGVGGIAVLCPMLISEIAPKHLRGTLVSCYQLMI
TAGIFLGYCTNYGTKSYSNSVQWRVPLGLCFAWSLFMIGALTLVPESPRYLCEVNKVE
DAKRSIAKSNKVSPEDPAVQAELDLIMAGIEAEKLAGNASWGELFSTKTKVFQRLLMG
VFVQMFQQLTGNNYFFYYGTVIFKSVGLDDSFETSIVIGVVNFASTFFSLWTVENLGH
RKCLLLGAATMMACMVIYASVGVTRLYPHGKSQPSSKGAGNCMIVFTCFYIFCYATTW
APVAWVITAESFPLRVKSKCMALASASNWVWGFLIAFFTPFITSAINFYYGYVFMGCL
VAMFFYVFFFVPETKGLSLEEIQELWEEGVLPWKSEGWIPSSRRGNNYDLEDLQHDDK
PWYKAMLE"
gene complement(292394..293572)
/gene="SRL2"
/locus_tag="YLR082C"
/db_xref="GeneID:850771"
mRNA complement(292394..293572)
/gene="SRL2"
/locus_tag="YLR082C"
/product="Srl2p"
/transcript_id="NM_001181969.1"
/db_xref="GI:296146618"
/db_xref="GeneID:850771"
CDS complement(292394..293572)
/gene="SRL2"
/locus_tag="YLR082C"
/note="hypothetical protein; overexpression suppresses the
lethality caused by a rad53 null mutation"
/codon_start=1
/product="Srl2p"
/protein_id="NP_013183.1"
/db_xref="GI:6323111"
/db_xref="SGD:S000004072"
/db_xref="GeneID:850771"
/translation="MSNFKNFTLNSFEDYYGKPSETPKMEEEKLEVTNVNASSSKKVH
KSKKSTSKYDQKNVFRNSMTGIAQILPTKPVKIIEQNIDFANPKSFDLLQSTHTICFN
KRINTTNTKLNVETHTSSDIDNDILHVGAPTDLGGNSNDEAETRQLRKFRWSNNKEKS
LCEKLTVIYWALLLHTTKRASKRRPILCHQMIAEFFNRVYKEKSRVPITSRYIRDNLV
AWVTQGKELHEKGWVGDAKTGDLQEQFNIATVKLYESAEDGRLSIGKDKPFREENTGS
DSLVRAEEDSTAVTNENGHISSEKNLKKDRRESIRNQILTLDLNDEDFFQNVMKVLSA
IDEPELRQYVIVISELVSMEMDDGKTVREKLRDVELNINRLQVDIKEIKEMLVTLINK
"
gene complement(294091..296094)
/gene="EMP70"
/locus_tag="YLR083C"
/gene_synonym="TMN1"
/db_xref="GeneID:850772"
mRNA complement(294091..296094)
/gene="EMP70"
/locus_tag="YLR083C"
/gene_synonym="TMN1"
/product="Emp70p"
/transcript_id="NM_001181970.1"
/db_xref="GI:296146619"
/db_xref="GeneID:850772"
CDS complement(294091..296094)
/gene="EMP70"
/locus_tag="YLR083C"
/gene_synonym="TMN1"
/note="Protein with a role in cellular adhesion,
filamentous growth, and endosome-to-vacuole sorting;
similar to Tmn2p and Tmn3p; member of Transmembrane Nine
family of proteins with 9 transmembrane segments"
/codon_start=1
/product="Emp70p"
/protein_id="NP_013184.1"
/db_xref="GI:6323112"
/db_xref="SGD:S000004073"
/db_xref="GeneID:850772"
/translation="MIYKMAHVQLLLLYFFVSTVKAFYLPGVAPTTYRENDNIPLLVN
HLTPSMNYQHKDEDGNNVSGDKENFLYSYDYYYNRFHFCQPEKVEKQPESLGSVIFGD
RIYNSPFQLNMLQEKECESLCKTVIPGDDAKFINKLIKNGFFQNWLIDGLPAAREVYD
GRTKTSFYGAGFNLGFVQVTQGTDIEATPKGAETTDKDVELETRNDRNMVKTYELPYF
ANHFDIMIEYHDRGEGNYRVVGVIVEPVSIKRSSPGTCETTGSPLMLDEGNDNEVYFT
YSVKFNESATSWATRWDKYLHVYDPSIQWFSLINFSLVVVLLSSVVIHSLLRALKSDF
ARYNELNLDDDFQEDSGWKLNHGDVFRSPSQSLTLSILVGSGVQLFLMVTCSIFFAAL
GFLSPSSRGSLATVMFILYALFGFVGSYTSMGIYKFFNGPYWKANLILTPLLVPGAIL
LIIIALNFFLMFVHSSGVIPASTLFFMVFLWFLFSIPLSFAGSLIARKRCHWDEHPTK
TNQIARQIPFQPWYLKTIPATLIAGIFPFGSIAVELYFIYTSLWFNKIFYMFGFLFFS
FLLLTLTSSLVTILITYHSLCLENWKWQWRGFIIGGAGCALYVFIHSILFTKFKLGGF
TTIVLYVGYSSVISLLCCLVTGSIGFISSMLFVRKIYSSIKVD"
gene complement(296589..300251)
/gene="RAX2"
/locus_tag="YLR084C"
/db_xref="GeneID:850773"
mRNA complement(296589..300251)
/gene="RAX2"
/locus_tag="YLR084C"
/product="Rax2p"
/transcript_id="NM_001181971.1"
/db_xref="GI:296146620"
/db_xref="GeneID:850773"
CDS complement(296589..300251)
/gene="RAX2"
/locus_tag="YLR084C"
/note="N-glycosylated protein involved in the maintenance
of bud site selection during bipolar budding; localization
requires Rax1p; RAX2 mRNA stability is regulated by Mpt5p"
/codon_start=1
/product="Rax2p"
/protein_id="NP_013185.1"
/db_xref="GI:6323113"
/db_xref="SGD:S000004074"
/db_xref="GeneID:850773"
/translation="MFVHRLWTLAFPFLVEISKASQLENIKSLLDIEDNVLPNLNISQ
NNSNAVQILGGVDALSFYEYTGQQNFTKEIGPETSSHGLVYYSNNTYIQLEDASDDTR
IDKITPFGVDSFILSGSGTINNISVGNQILYNLSTLSMTPIFNQSLGAVQAVLADNSS
IYFGGNFSYNNGSMTGYSALIWDSISNTTQLLPFGGFGENSSVNSIVKLNNDNILFAG
QFYTLDDPSALISSSNNGTNSTSSLNATTLELGQRIPLRYASWDSQGSTTFASDSLVC
PNTNEDAWLYPDTSGSLVCNLPYEVSPTKIRLYNSQRSDSEISVFQILTDPSSSIMNL
TYLDPLSGELKNCGEFCPLYSRATLLSASQNVSSSMDMITFIDNNKTDVKWTSDFQDF
AFVNELPVSSLKFVALNSYGGSVGLSGLELYQDTFSTYANDSLNEYGCSALTNDSSSS
TLSSNDWYNGLTGESYIAAKYVPDQNEPIPRVKFYPNIIHPGHYTINMYTPGCLQDNT
CSARGIVNVTMWNQQNNTIMKTYLIYQNNDNLKYDQIYSGYLDFSPEIVLEYVSGIYT
TNTATVVVADQVNVITVSLDAFNTLSDSSNAKKETLLNGILQYQKSNFTSTRLNETKV
GNTTLNLFPVKNYPKNSSLYADIYDNKLVIGGVSNRISIVDLNDDFEVTSSKNQTIQG
DVHGITKTNQGLLIFGDILSSNNQSAVFLFNGSFENVFNQSRTVNSALNISLANNDFI
VLDNDYVVNASSNALIRNSSSFSLSLWAAGNNGDGDVLFSGAVSHMQYGNLNGSVRFL
NENEIEPLNLEGGIVPYLGAYLNESATAYAYEVDSLNKIYFSNEVYPSWNWSSGITQM
LYADNQTLLAVSAGSSTTAELSIFDLRNLTMIANETLGSNARINALVNFEKNCSMLVG
GDFQMTEPNCTGLCLYNYESKTWSTFLNNTIFGEITQLSFTNSSELIISGLFETKEYQ
SIRLGSFNLTNSTMIPLLSGSEGKLNSFTVTEDSIVAWNDTSLFIYRNQEWNITSLPG
NASSISSVSAIYTDIESNTLNKRGINNVNNGSILLLNGNFNISQYGYLQSLLFDFQKW
TPYFISETTNTSNYNPIIFINRDVSTEFNSQSPLANVNITVTSPQSTSSQPPSSSASS
ESKSKSKKKKIGRGFVVLIGLALALGTVSVLGIAGVILAYVFKDPEGDYKPIKPRIDE
NEMLDTVPPEKLMKFV"
gene complement(300673..301989)
/gene="ARP6"
/locus_tag="YLR085C"
/db_xref="GeneID:850774"
mRNA complement(300673..301989)
/gene="ARP6"
/locus_tag="YLR085C"
/product="Arp6p"
/transcript_id="NM_001181972.1"
/db_xref="GI:296146621"
/db_xref="GeneID:850774"
CDS complement(300673..301989)
/gene="ARP6"
/locus_tag="YLR085C"
/note="Actin-related protein that binds nucleosomes; a
component of the SWR1 complex, which exchanges histone
variant H2AZ (Htz1p) for chromatin-bound histone H2A"
/codon_start=1
/product="Arp6p"
/protein_id="NP_013186.1"
/db_xref="GI:6323114"
/db_xref="SGD:S000004075"
/db_xref="GeneID:850774"
/translation="METPPIVIDNGSYEIKFGPSTNKKPFRALNALAKDKFGTSYLSN
HIKNIKDISSITFRRPHELGQLTLWELESCIWDYCLFNPSEFDGFDLKEGKGHHLVAS
ESCMTLPELSKHADQVIFEEYEFDSLFKSPVAVFVPFTKSYKGEMRTISGKDEDIDIV
RGNSDSTNSTSSESKNAQDSGSDYHDFQLVIDSGFNCTWIIPVLKGIPYYKAVKKLDI
GGRFLTGLLKETLSFRHYNMMDETILVNNIKEQCLFVSPVSYFDSFKTKDKHALEYVL
PDFQTSFLGYVRNPRKENVPLPEDAQIITLTDELFTIPETFFHPEISQITKPGIVEAI
LESLSMLPEIVRPLMVGNIVCTGGNFNLPNFAQRLAAELQRQLPTDWTCHVSVPEGDC
ALFGWEVMSQFAKTDSYRKARVTREEYYEHGPDWCTKHRFGYQNWI"
gene 302243..306499
/gene="SMC4"
/locus_tag="YLR086W"
/db_xref="GeneID:850775"
mRNA 302243..306499
/gene="SMC4"
/locus_tag="YLR086W"
/product="condensin subunit SMC4"
/transcript_id="NM_001181973.1"
/db_xref="GI:296146622"
/db_xref="GeneID:850775"
CDS 302243..306499
/gene="SMC4"
/locus_tag="YLR086W"
/note="Subunit of the condensin complex; reorganizes
chromosomes during cell division; forms a complex with
Smc2p that has ATP-hydrolyzing and DNA-binding activity;
required for tRNA gene clustering at the nucleolus;
potential Cdc28p substrate"
/codon_start=1
/product="condensin subunit SMC4"
/protein_id="NP_013187.1"
/db_xref="GI:6323115"
/db_xref="SGD:S000004076"
/db_xref="GeneID:850775"
/translation="MSDSPLSKRQKRKSAQEPELSLDQGDAEEDSQVENRVNLSENTP
EPDLPALEASYSKSYTPRKLVLSSGENRYAFSQPTNSTTTSLHVPNLQPPKTSSRGRD
HKSYSQSPPRSPGRSPTRRLELLQLSPVKNSRVELQKIYDRHQSSSKQQSRLFINELV
LENFKSYAGKQVVGPFHTSFSAVVGPNGSGKSNVIDSMLFVFGFRANKMRQDRLSDLI
HKSEAFPSLQSCSVAVHFQYVIDESSGTSRIDEEKPGLIITRKAFKNNSSKYYINEKE
SSYTEVTKLLKNEGIDLDHKRFLILQGEVENIAQMKPKAEKESDDGLLEYLEDIIGTA
NYKPLIEERMGQIENLNEVCLEKENRFEIVDREKNSLESGKETALEFLEKEKQLTLLR
SKLFQFKLLQSNSKLASTLEKISSSNKDLEDEKMKFQESLKKVDEIKAQRKEIKDRIS
SCSSKEKTLVLERRELEGTRVSLEERTKNLVSKMEKAEKTLKSTKHSISEAENMLEEL
RGQQTEHETEIKDLTQLLEKERSILDDIKLSLKDKTKNISAEIIRHEKELEPWDLQLQ
EKESQIQLAESELSLLEETQAKLKKNVETLEEKILAKKTHKQELQDLILDLKKKLNSL
KDERSQGEKNFTSAHLKLKEMQKVLNAHRQRAMEARSSLSKAQNKSKVLTALSRLQKS
GRINGFHGRLGDLGVIDDSFDVAISTACPRLDDVVVDTVECAQHCIDYLRKNKLGYAR
FILLDRLRQFNLQPISTPENVPRLFDLVKPKNPKFSNAFYSVLRDTLVAQNLKQANNV
AYGKKRFRVVTVDGKLIDISGTMSGGGNHVAKGLMKLGTNQSDKVDDYTPEEVDKIER
ELSERENNFRVASDTVHEMEEELKKLRDHEPDLESQISKAEMEADSLASELTLAEQQV
KEAEMAYVKAVSDKAQLNVVMKNLERLRGEYNDLQSETKTKKEKIKGLQDEIMKIGGI
KLQMQNSKVESVCQKLDILVAKLKKVKSASKKSGGDVVKFQKLLQNSERDVELSSDEL
KVIEEQLKHTKLALAENDTNMNETLNLKVELKEQSEQLKEQMEDMEESINEFKSIEIE
MKNKLEKLNSLLTYIKSEITQQEKGLNELSIRDVTHTLGMLDDNKMDSVKEDVKNNQE
LDQEYRSCETQDESEIKDAETSCDNYHPMNIDETSDEVSRGIPRLSEDELRELDVELI
ESKINELSYYVEETNVDIGVLEEYARRLAEFKRRKLDLNNAVQKRDEVKEQLGILKKK
RFDEFMAGFNIISMTLKEMYQMITMGGNAELELVDSLDPFSEGVTFSVMPPKKSWRNI
TNLSGGEKTLSSLALVFALHKYKPTPLYVMDEIDAALDFRNVSIVANYIKERTKNAQF
IVISLRNNMFELAQQLVGVYKRDNRTKSTTIKNIDILNRT"
gene complement(306855..315731)
/gene="CSF1"
/locus_tag="YLR087C"
/db_xref="GeneID:850776"
mRNA complement(306855..315731)
/gene="CSF1"
/locus_tag="YLR087C"
/product="Csf1p"
/transcript_id="NM_001181974.1"
/db_xref="GI:296146623"
/db_xref="GeneID:850776"
CDS complement(306855..315731)
/gene="CSF1"
/locus_tag="YLR087C"
/note="Protein required for fermentation at low
temperature; the authentic, non-tagged protein is detected
in highly purified mitochondria in high-throughput
studies"
/codon_start=1
/product="Csf1p"
/protein_id="NP_013188.1"
/db_xref="GI:6323116"
/db_xref="SGD:S000004077"
/db_xref="GeneID:850776"
/translation="MEAISQLRGVPLTHQKDFSWVFLVDWILTVVVCLTMIFYMGRIY
AYLVSFILEWLLWKRAKIKINVETLRVSLLGGRIHFKNLSVIHKDYTISVLEGSLTWK
YWLLNCRKAELIENNKSSSGKKAKLPCKISVECEGLEIFIYNRTVAYDNVINLLSKDE
RDKFEKYLNEHSFPEPFSDGSSADKLDEDLSESAYTTNSDASIVNDRDYQETDIGKHP
KLLMFLPIELKFSRGSLLLGNKFTPSVMILSYESGKGIIDVLPPKERLDLYRNKTQME
FKNFEISIKQNIGYDDAIGLKFKIDRGKVSKLWKTFVRVFQIVTKPVVPKKTKKSAGT
SDDNFYHKWKGLSLYKASAGDAKASDLDDVEFDLTNHEYAKFTSILKCPKVTIAYDVD
VPGVVPHGAHPTIPDIDGPDVGNNGAPPDFALDVQIHGGSICYGPWAQRQVSHLQRVL
SPVVSRTAKPIKKLPPGSRRIYTLFRMNISIMEDTTWRIPTRESSKDPEFLKHYKETN
EEYRPFGWMDLRFCKDTYANFNISVCPTVQGFQNNFHVHFLETEIRSSVNHDILLKSK
VFDIDGDIGYPLGWNSKAIWIINMKSEQLEAFLLREHITLVADTLSDFSAGDPTPYEL
FRPFVYKVNWEMEGYSIYLNVNDHNIVNNPLDFNENCYLSLHGDKLSIDVTVPRESIL
GTYTDMSYEISTPMFRMMLNTPPWNTLNEFMKHKEVGRAYDFTIKGSYLLYSELDIDN
VDTLVIECNSKSTVLHCYGFVMRYLTNVKMNYFGEFFNFVTSEEYTGVLGAREVGDVT
TKSSVADLASTVDSGYQNSSLKNESEDKGPMKRSDLKRTTNETDIWFTFSVWDGALIL
PETIYSFDPCIALHFAELVVDFRSCNYYMDIMAVLNGTSIKRHVSKQINEVFDFIRRN
NGADEQEHGLLSDLTIHGHRMYGLPPTEPTYFCQWDINLGDLCIDSDIEFIKGFFNSF
YKIGFGYNDLENILLYDTETINDMTSLTVHVEKIRIGLKDPVMKSQSVISAESILFTL
IDFENEKYSQRIDVKIPKLTISLNCVMGDGVDTSFLKFETKLRFTNFEQYKDIDKKRS
EQRRYITIHDSPYHRCPFLLPLFYQDSDTYQNLYGAIAPSSSIPTLPLPTLPDTIDYI
IEDIVGEYATLLETTNPFKNIFAETPSTMEPSRASFSEDDNDEEADPSSFKPVAFTED
RNHERDNYVVDVSYILLDVDPLLFIFAKSLLEQLYSENMVQVLDDIEIGIVKRLSNLQ
EGITSISNIDIHIAYLNLIWQETGEEGFELYLDRIDYQMSEKSLEKNRTNKLLEVAAL
AKVKTVRVTVNQKKNPDLSEDRPPALSLGIEGFEVWSSTEDRQVNSLNLTSSDITIDE
SQMEWLFEYCSDQGNLIQEVCTSFNSIQNTRSNSKTELISKLTAASEYYQISHDPYVI
TKPAFIMRLSKGHVRENRSWKIITRLRHILTYLPDDWQSNIDEVLKEKKYTSAKDAKN
IFMSVFSTWRNWEFSDVARSYIYGKLFTAENEKHKQNLIKKLLKCTMGSFYLTVYGEG
YEVEHNFVVADANLVVDLTPPVTSLPSNREETIEITGRVGSVKGKFSDRLLKLQDLIP
LIAAVGEDDKSDPKKELSKQFKMNTVLLVDKSELQLVMDQTKLMSRTVGGRVSLLWEN
LKDSTSQAGSLVIFSQKSEVWLKHTSVILGEAQLRDFSVLATTEAWSHKPTILINNQC
ADLHFRAMSSTEQLVTAITEIRESLMMIKERIKFKPKSKKKSQFVDQKINTVLSCYFS
NVSSEVMPLSPFYIRHEAKQLDIYFNKFGSNEILLSIWDTDFFMTSHQTKEQYLRFSF
GDIEIKGGISREGYSLINVDISISMIKLTFSEPRRIVNSFLQDEKLASQGINLLYSLK
PLFFSSNLPKKEKQAPSIMINWTLDTSITYFGVLVPVASTYFVFELHMLLLSLTNTNN
GMLPEETKVTGQFSIENILFLIKERSLPIGLSKLLDFSIKVSTLQRTVDTEQSFQVES
SHFRVCLSPDSLLRLMWGAHKLLDLSHYYSRRHAPNIWNTKMFTGKSDKSKEMPINFR
SIHILSYKFCIGWIFQYGAGSNPGLMLGYNRLFSAYEKDFGKFTVVDAFFSVANGNTS
STFFSEGNEKDKYNRSFLPNMQISYWFKRCGELKDWFFRFHGEALDVNFVPSFMDVIE
STLQSMRAFQELKKNILDVSESLRAENDNSYASTSVESASSSLAPFLDNIRSVNSNFK
YDGGVFRVYTYEDIETKSEPSFEIKSPVVTINCTYKHDEDKVKPHKFRTLITVDPTHN
TLYAGCAPLLMEFSESLQKMIKKHSTDEKPNFTKPSSQNVDYKRLLDQFDVAVKLTSA
KQQLSLSCEPKAKVQADVGFESFLFSMATNEFDSEQPLEFSLTLEHTKASIKHIFSRE
VSTSFEVGFMDLTLLFTHPDVISMYGTGLVSDLSVFFNVKQLQNLYLFLDIWRFSSIL
HTRPVQRTVNKEIEMSSLTSTNYADAGTEIPWCFTLIFTNVSGDVDLGPSLGMISLRT
QRTWLATDHYNEKRQLLHAFTDGISLTSEGRLSGLFEVANASWLSEVKWPPEKSKNTH
PLVSTSLNIDDIAVKAAFDYHMFLIGTISNIHFHLHNEKDAKGVLPDLLQVSFSSDEI
ILSSTALVVANILDIYNTIVRMRQDNKISYMETLRDSNPGESRQPILYKDILRSLKLL
RTDLSVNISSSKVQISPISLFDVEVLVIRIDKVSIRSETHSGKKLKTDLQLQVLDVSA
ALSTSKEELDEEVGASIAIDDYMHYASKIVGGTIIDIPKLAVHMTTLQEEKTNNLEYL
FACSFSDKISVRWNLGPVDFIKEMWTTHVKALAVRRSQVANISFGQTEEELEESIKKE
EAASKFNYIALEEPQIEVPQIRDLGDATPPMEWFGVNRKKFPKFTHQTAVIPVQKLVY
LAEKQYVKILDDTH"
gene 316107..317951
/gene="GAA1"
/locus_tag="YLR088W"
/gene_synonym="END2"
/db_xref="GeneID:850777"
mRNA 316107..317951
/gene="GAA1"
/locus_tag="YLR088W"
/gene_synonym="END2"
/product="Gaa1p"
/transcript_id="NM_001181975.1"
/db_xref="GI:296146624"
/db_xref="GeneID:850777"
CDS 316107..317951
/gene="GAA1"
/locus_tag="YLR088W"
/gene_synonym="END2"
/note="Subunit of the GPI
(glycosylphosphatidylinositol):protein transamidase
complex, removes the GPI-anchoring signal and attaches GPI
to proteins in the ER"
/codon_start=1
/product="Gaa1p"
/protein_id="NP_013189.1"
/db_xref="GI:6323117"
/db_xref="SGD:S000004078"
/db_xref="GeneID:850777"
/translation="MALLEKLHRRIVDMGLVPRIIALLPVISMLCALFGFISIAILPM
DGQYRRTYISENALMPSQAYSYFRESEWNILRGYRSQIKEMVNMTSMERNNLMGSWLQ
EFGTKTAIYENEQYGETLYGVMHAPRGDGTEAMVLAVPWFNSDDEFNIGGAALGVSLA
RFFSRWPVWSKNIIVVFSENPRAALRSWVEAYHTSLDLTGGSIEAAVVLDYSSTEDFF
EYVEISYDGLNGELPNLDLVNIAISITEHEGMKVSLHGLPSDQLTNNNFWSRLKILCL
GIRDWALSGVKKPHGNEAFSGWRIQSVTLKAHGNSGHDITTFGRIPEAMFRSINNLLE
KFHQSFFFYLLLAPRQFVSISSYLPSAVALSIAFAISSLNAFINNAYANISLFSEYNL
VALLVWFVSLVISFVVSQAFLLIPSSGLLMTISMASCFLPLILSRKIHISEPLSYRLK
NVAFLYFSLVSTSLLMINFAMALLIGTLAFPMTFVKTIVESSSEHEVTTQSSNPIKTE
PKDEIELVENHMDTTPATPQQQKQKLKNLVLLILTNPFISITLFGLFFDDEFHGFDII
NKLVSAWLDLKCWSWFVLCIGWLPCWLLILASSFESKSVVVRSKEKQS"
gene complement(318237..320015)
/gene="ALT1"
/locus_tag="YLR089C"
/db_xref="GeneID:850778"
mRNA complement(318237..320015)
/gene="ALT1"
/locus_tag="YLR089C"
/product="alanine transaminase ALT1"
/transcript_id="NM_001181976.1"
/db_xref="GI:296146625"
/db_xref="GeneID:850778"
CDS complement(318237..320015)
/gene="ALT1"
/locus_tag="YLR089C"
/EC_number="2.6.1.2"
/note="Alanine transaminase (glutamic pyruvic
transaminase); involved in alanine biosynthetic and
catabolic processes; expression is induced in the presence
of alanine; repression is mediated by Nrg1p; the
authentic, non-tagged protein is detected in highly
purified mitochondria in high-throughput studies;
paralogous gene ALT2 is catalytically inactive"
/codon_start=1
/product="alanine transaminase ALT1"
/protein_id="NP_013190.1"
/db_xref="GI:6323118"
/db_xref="SGD:S000004079"
/db_xref="GeneID:850778"
/translation="MLSLSAKNHFTVSNSITHVIKSYHIRTLTSSAEKMPHITTPFST
SASSTKLKAFRKVRPVLQRHSSSWIVAQNHRRSLSGQSSLNDLRHLNRFPHHTLKTSN
NEFYPAEQLTLEDVNENVLKAKYAVRGAIPMRAEELKAQLEKDPQSLPFDRIINANIG
NPQQLQQKPLTYYRQVLSLLQYPELLNQNEQQLVDSKLFKLDAIKRAKSLMEDIGGSV
GAYSSSQGVEGIRKSVAEFITKRDEGEISYPEDIFLTAGASAAVNYLLSIFCRGPETG
VLIPIPQYPLYTATLALNNSQALPYYLDENSGWSTNPEEIETVVKEAIQNEIKPTVLV
VINPGNPTGAVLSPESIAQIFEVAAKYGTVVIADEVYQENIFPGTKFHSMKKILRHLQ
REHPGKFDNVQLASLHSTSKGVSGECGQRGGYMELTGFSHEMRQVILKLASISLCPVV
TGQALVDLMVRPPVEGEESFESDQAERNSIHEKLITRAMTLYETFNSLEGIECQKPQG
AMYLFPKIDLPFKAVQEARHLELTPDEFYCKKLLESTGICTVPGSGFGQEPGTYHLRT
TFLAPGLEWIKKWESFHKEFFDQYRD"
gene 320701..322080
/gene="XDJ1"
/locus_tag="YLR090W"
/db_xref="GeneID:850779"
mRNA 320701..322080
/gene="XDJ1"
/locus_tag="YLR090W"
/product="Xdj1p"
/transcript_id="NM_001181977.1"
/db_xref="GI:296146626"
/db_xref="GeneID:850779"
CDS 320701..322080
/gene="XDJ1"
/locus_tag="YLR090W"
/note="Putative chaperone, homolog of E. coli DnaJ,
closely related to Ydj1p; the authentic, non-tagged
protein is detected in highly purified mitochondria in
high-throughput studies"
/codon_start=1
/product="Xdj1p"
/protein_id="NP_013191.1"
/db_xref="GI:6323119"
/db_xref="SGD:S000004080"
/db_xref="GeneID:850779"
/translation="MSGSDRGDRLYDVLGVTRDATVQEIKTAYRKLALKHHPDKYVDQ
DSKEVNEIKFKEITAAYEILSDPEKKSHYDLYGDDNGAASSGGANGFGDEDFMNFFNN
FFNNGSHDGNNFPGEYDAYEEGNSTSSKDIDIDISLTLKDLYMGKKLKFDLKRQVICI
KCHGSGWKPKRKIHVTHDVECESCAGKGSKERLKRFGPGLVASQWVVCEKCNGKGKYT
KRPKNPKNFCPDCAGLGLLSKKEIITVNVAPGHHFNDVITVKGMADEEIDKTTCGDLK
FHLTEKQENLEQKQIFLKNFDDGAGEDLYTSITISLSEALTGFEKFLTKTFDDRLLTL
SVKPGRVVRPGDTIKIANEGWPILDNPHGRCGDLYVFVHIEFPPDNWFNEKSELLAIK
TNLPSSSSCASHATVNTEDDSNLTNNETISNFRIIHTDDLPEGIRPFKPEAQDSAHQK
ARSSYCCIQ"
gene 322297..323178
/gene="GEP5"
/locus_tag="YLR091W"
/gene_synonym="RRG5"
/db_xref="GeneID:850780"
mRNA 322297..323178
/gene="GEP5"
/locus_tag="YLR091W"
/gene_synonym="RRG5"
/product="Gep5p"
/transcript_id="NM_001181978.1"
/db_xref="GI:296146627"
/db_xref="GeneID:850780"
CDS 322297..323178
/gene="GEP5"
/locus_tag="YLR091W"
/gene_synonym="RRG5"
/note="hypothetical protein, required for mitochondrial
genome maintenance; detected in highly purified
mitochondria in high-throughput studies; null mutant has
decreased levels of cardiolipin and
phosphatidylethanolamine"
/codon_start=1
/product="Gep5p"
/protein_id="NP_013192.1"
/db_xref="GI:6323120"
/db_xref="SGD:S000004081"
/db_xref="GeneID:850780"
/translation="MASQVNALLLPVIESTPLHQITKVALTTTLTSKQSDYKFKEIAV
PLTKSLQLYEKAQRRQDLRASLKALESIIYQTHFQWNNPLPRHAHLFQKHYHFLLTHW
PFENHRDLVDSIAVNNGKLNSTSSRSVWLKADWITLFNVKNPWVQTPPSLMRLSGTDL
DTFTPERIFLINSLGNHYKFLIANSHLSYNHKKYPSPGVQIPVRNALGEVSPAKQIAQ
LFARQLSHIYKSLFIENPPLSPENELALTAVFYDETVERRLRRLYMRACARAYTTTNA
DSTTEPLMFHCTRWEVD"
gene 323544..326225
/gene="SUL2"
/locus_tag="YLR092W"
/db_xref="GeneID:850781"
mRNA 323544..326225
/gene="SUL2"
/locus_tag="YLR092W"
/product="Sul2p"
/transcript_id="NM_001181979.1"
/db_xref="GI:296146628"
/db_xref="GeneID:850781"
CDS 323544..326225
/gene="SUL2"
/locus_tag="YLR092W"
/note="High affinity sulfate permease; sulfate uptake is
mediated by specific sulfate transporters Sul1p and Sul2p,
which control the concentration of endogenous activated
sulfate intermediates"
/codon_start=1
/product="Sul2p"
/protein_id="NP_013193.1"
/db_xref="GI:6323121"
/db_xref="SGD:S000004082"
/db_xref="GeneID:850781"
/translation="MSREGYPNFEEVEIPDFQETNNTVPDLDDLELEYDQYKNNENND
TFNDKDLESNSVAKHNAVNSSKGVKGSKIDYFNPSDVSLYDNSVSQFEETTVSLKEYY
DHSIRSHLTVKGACSYLKSVFPIINWLPHYNFSWFTADLIAGITIGCVLVPQSMSYAQ
VATLPAQYGLYSSFIGAYSYSFFATSKDVCIGPVAVMSLQTAKVIADVTAKYPDGDSA
ITGPVIATTLALLCGIISAAVGFLRLGFLVELISLNAVAGFMTGSAFNILWGQVPALM
GYNSLVNTRAATYKVVIETLKHLPDTKLDAVFGLIPLFLLYVWKWWCGTYGPRLNDRY
NSKNPRLHKIIKWTYFYAQASRNGIIIIVFTCIGWAITRGKSKSERPISILGSVPSGL
KEVGVFHVPPGLMSKLGPNLPASIIVLLLEHIAISKSFGRINDYKVVPDQELIAIGVS
NLLGTFFNAYPATGSFSRSALKAKCNVRTPLSGLFSGSCVLLALYCLTGAFFYIPKAT
LSAVIIHAVSDLLASYQTTWNFWKMNPLDFICFIVTVLITVFASIEDGIYFAMCWSCA
MLILKVAFPAGKFLGRVEVAEVTDAYVRPDSDVVSYVSENNNGISTLEDGGEDDKESS
TKYVTNSSKKIETNVQTKGFDSPSSSISQPRIKYHTKWIPFDHKYTRELNPDVQILPP
PDGVLVYRLSESYTYLNCSRHYNIITEEVKKVTRRGQLIRHRKKSDRPWNDPGPWEAP
AFLKNLKFWKKRENDPESMENAPSTSVDVERDDRPLLKILCLDFSQVAQTDATALQSL
VDLRKAINQYADRQVEFHFVGIISPWVKRGLISRGFGTLNEEYSDESIVAGHTSYHVA
RVPQGEENPEKYSVYTASGTNLPFFHIDIPDFAKWDI"
gene complement(326513..327415)
/gene="NYV1"
/locus_tag="YLR093C"
/gene_synonym="MAM2"
/db_xref="GeneID:850782"
mRNA complement(join(326513..327258,327400..327415))
/gene="NYV1"
/locus_tag="YLR093C"
/gene_synonym="MAM2"
/product="Nyv1p"
/transcript_id="NM_001181980.1"
/db_xref="GI:296146629"
/db_xref="GeneID:850782"
CDS complement(join(326513..327258,327400..327415))
/gene="NYV1"
/locus_tag="YLR093C"
/gene_synonym="MAM2"
/note="v-SNARE component of the vacuolar SNARE complex
involved in vesicle fusion; inhibits ATP-dependent Ca(2+)
transport activity of Pmc1p in the vacuolar membrane"
/codon_start=1
/product="Nyv1p"
/protein_id="NP_013194.2"
/db_xref="GI:9755337"
/db_xref="SGD:S000004083"
/db_xref="GeneID:850782"
/translation="MKRFNVSYVEVIKNGETISSCFQPFQKNENYGTITSANEQITPV
IFHNLIMDMVLPKVVPIKGNKVTKMSMNLIDGFDCFYSTDDHDPKTVYVCFTLVDMPK
ILPIRILSGLQEYESNATNELLSSHVGQILDSFHEELVEYRNQTLNSSGNGQSSNGNG
QNTISDIGDATEDQIKDVIQIMNDNIDKFLERQERVSLLVDKTSQLNSSSNKFRRKAV
NIKEIMWWQKVKNITLLTFTIILFVSAAFMFFYLW"
gene complement(327730..329238)
/gene="GIS3"
/locus_tag="YLR094C"
/db_xref="GeneID:850783"
mRNA complement(327730..329238)
/gene="GIS3"
/locus_tag="YLR094C"
/product="Gis3p"
/transcript_id="NM_001181981.1"
/db_xref="GI:296146630"
/db_xref="GeneID:850783"
CDS complement(327730..329238)
/gene="GIS3"
/locus_tag="YLR094C"
/codon_start=1
/product="Gis3p"
/protein_id="NP_013195.1"
/db_xref="GI:6323123"
/db_xref="SGD:S000004084"
/db_xref="GeneID:850783"
/translation="MLLDVNTNHTLMHDAHVHEHCLIKSIRDDGALHSWSDSSKVFYP
KSFYATATNKKNNKLASASMNKTATSNRTVSDEIYFHSTKPQFDGQGSAERTRTLTKR
NSFKRTRILKARDDSELLNENRSSLMTPSLSSVMSQVRKTNSAKTLSGECPIHEGHLT
QSIKRKFSEEAQSDCSSLSSSKLHPLTDDIADAVDLQTPAIGDEVLAEPVVPKMKIIN
INDLDLFDDWEVKDLVDIFPPVYERRPRSSSALSLVSASSDAKLRPTSVDFQIIDKKG
GKTSRRKSRSKSTTENMIYENDLVELEQWPSASPSPETDGSIASSELLPNKRIRQKSL
NTNFLKLYSIETSCKRKSILPEVEVDDHLLKQLTYSEIRSLEIKKEPNVSTNDIKLAL
ITRKKLWSDMVHETRNDLFGDSTPWNLHFVATTSNTEPSQGRESASEHATADLKSSLV
RVHSDVKPWFNNGGTMLKPCGKLNLGKVTNKTSAPTREIQYVVKGWCDSRFL"
gene complement(329677..332115)
/gene="IOC2"
/locus_tag="YLR095C"
/db_xref="GeneID:850784"
mRNA complement(329677..332115)
/gene="IOC2"
/locus_tag="YLR095C"
/product="Ioc2p"
/transcript_id="NM_001181982.1"
/db_xref="GI:296146631"
/db_xref="GeneID:850784"
CDS complement(329677..332115)
/gene="IOC2"
/locus_tag="YLR095C"
/note="Member of a complex (Isw1b) with Isw1p and Ioc4p
that exhibits nucleosome-stimulated ATPase activity and
acts within coding regions to coordinate transcription
elongation with termination and processing, contains a PHD
finger motif"
/codon_start=1
/product="Ioc2p"
/protein_id="NP_013196.1"
/db_xref="GI:6323124"
/db_xref="SGD:S000004085"
/db_xref="GeneID:850784"
/translation="MRTKRTRGTRNVGASMPAGAANADSEDWKEYVSEDIIAQLNKHQ
LPYSEILDEKIADLANHWHFQYVMAWLSNVCESYTTTTFNTDQYGGSSTKCLWKNIKF
DEGVFVTDVFSKIDGKDSNYYNDEVDVDEGSQNLYDRIRLQLLHQLAGNKSGQLKDWN
VIVNHHLQNSSAYSDLVTDLPFLELEIARQFDIIYSIIKLIEMKNMIFKNYLANNLHL
FTFSEVILDDDNSGGEEMKSLFALPNVGVLVKKTIHRVKEGSSSQVSQTLNIPIKLQN
CTIKESDPDIPDSVELIHLEYSHDIDAYLQSITIDYDVITTNWGSMLEYWSENKSSKA
IDEFITNLIPVYAEHRLYSAKLLANREKERAIAELMTRRKRSSRLVAKEEENKKKDLE
SEWFEKLDEREQFIRHRNKLVSKEIKKIKDLLWNQLWQLYDQDYRDEKLTRRNELKDR
SGSGTPFFETSLGREEDNPLNEIDIGVLDHGPNFQSSIIPVEPPIPGTVGPLQTGDVP
ELPSDFCITKEELDELANYGIFTPQQEPDNQDSVFQCPGEPELAPMIITEDTETDLFN
NRPLICCDHCYRWQHWECQPPKIIELISSTTKSPQHTLSQRDFGVIIMGNSHGNRRSS
RRPQSTLEPSTKSSRPTDKRKPLSECSTFICAWCIRDLELELRNIFVPELKIIRAKQR
KQQEDRERRKKMKEEKKRLEELAKKRELTESVSPPVFNNAFANMSSSTTPSIAAYEKT
NPAINPAPNVNAAHPIITYSQQTGSKTVPQAPQAPQTSQASIQPQQQQQQQQQQQPLH
PKEQNFHFQFPPTN"
gene 332590..336033
/gene="KIN2"
/locus_tag="YLR096W"
/db_xref="GeneID:850785"
mRNA 332590..336033
/gene="KIN2"
/locus_tag="YLR096W"
/product="Kin2p"
/transcript_id="NM_001181983.1"
/db_xref="GI:296146632"
/db_xref="GeneID:850785"
CDS 332590..336033
/gene="KIN2"
/locus_tag="YLR096W"
/EC_number="2.7.11.1"
/note="Serine/threonine protein kinase involved in
regulation of exocytosis; localizes to the cytoplasmic
face of the plasma membrane; closely related to Kin1p"
/codon_start=1
/product="Kin2p"
/protein_id="NP_013197.1"
/db_xref="GI:6323125"
/db_xref="SGD:S000004086"
/db_xref="GeneID:850785"
/translation="MPNPNTADYLVNPNFRTSKGGSLSPTPEAFNDTRVAAPATLRMM
GKQSGPRNDQQQAPLMPPADIKQGKEQAAQRQNDASRPNGAVELRQFHRRSLGDWEFL
ETVGAGSMGKVKLVKHRQTKEICVIKIVNRASKAYLHKQHSLPSPKNESEILERQKRL
EKEIARDKRTVREASLGQILYHPHICRLFEMCTMSNHFYMLFEYVSGGQLLDYIIQHG
SLKEHHARKFARGIASALQYLHANNIVHRDLKIENIMISSSGEIKIIDFGLSNIFDYR
KQLHTFCGSLYFAAPELLKAQPYTGPEVDIWSFGIVLYVLVCGKVPFDDENSSILHEK
IKKGKVDYPSHLSIEVISLLTRMIVVDPLRRATLKNVVEHPWMNRGYDFKAPSYVPNR
VPLTPEMIDSQVLKEMYRLEFIDDIEDTRRSLIRLVTEKEYIQLSQEYWDKLSNAKGL
SSSLNNNYLNSTAQQTLIQNHITSNPSQSGYNEPDSNFEDPTLAYHPLLSIYHLVSEM
VARKLAKLQRRQALALQAQAQQRQQQQQVALGTKVALNNNSPDIMTKMRSPQKEVVPN
PGIFQVPAIGTSGTSNNTNTSNKPPLHVMVPPKLTIPEQAHTSPTSRKSSDIHTELNG
VLKSTPVPVSGEYQQRSASPVVGEHQEKNTIGGIFRRISQSGQSQHPTRQQEPLPERE
PPTYMSKSNEISIKVPKSHSRTISDYIPSARRYPSYVPNSVDVKQKPAKNTTIAPPIR
SVSQKQNSDLPALPQNAELIVQKQRQKLLQENLDKLQINDNDNNNVNAVVDGINNDNS
DHYLSVPKGRKLHPSARAKSVGHARRESLKFTRPPIPAALPPSDMTNDNGFLGEANKE
RYNPVSSNFSTVPEDSTTYSNDTNNRLTSVYSQELTEKQILEEASKAPPGSMPSIDYP
KSMFLKGFFSVQTTSSKPLPIVRHNIISVLTRMNIDFKEVKGGFICVQQRPSIETAAV
PVITTTGVGLDSGKAMDLQNSLDSQLSSSYHSTASSASRNSSIKRQGSYKRGQNNIPL
TPLATNTHQRNSSIPMSPNYGNQSNGTSGELSSMSLDYVQQQDDILTTSRAQNINNVN
GQTEQTNTSGIKERPPIKFEIHIVKVRIVGLAGVHFKKVSGNTWLYKELASYILKELN
L"
gene complement(336231..337265)
/gene="HRT3"
/locus_tag="YLR097C"
/db_xref="GeneID:850786"
mRNA complement(336231..337265)
/gene="HRT3"
/locus_tag="YLR097C"
/product="SCF ubiquitin ligase complex subunit HRT3"
/transcript_id="NM_001181984.1"
/db_xref="GI:296146633"
/db_xref="GeneID:850786"
CDS complement(336231..337265)
/gene="HRT3"
/locus_tag="YLR097C"
/note="Putative SCF-ubiquitin ligase F-box protein, based
on both genetic and physical interactions and sequence
similarity; identified in association with Cdc53p, Skp1p
and Ubi4 in large and small-scale studies"
/codon_start=1
/product="SCF ubiquitin ligase complex subunit HRT3"
/protein_id="NP_013198.1"
/db_xref="GI:6323126"
/db_xref="SGD:S000004087"
/db_xref="GeneID:850786"
/translation="MIVDYEKDPRAKEAIAIWEKGVLKEKDGSMSDAINFYRSALKIH
DNVESLYRKKILDEWMLHKKLSGLSMTTDAPDEQNETGKDDLSVEENAELQPCWILEI
LPDDILLRIIKKVILMSGESWVNLSMTCSTFSKLCFHDSVPFKTFAKYIYSKQIYDKM
AMDLNGITDINTFEKEIWRGDDYRMLRERPYIKFEGVYISVVNYVRYGSNAESSLSLL
KPVHMITYYRYFRFYENGQCLRLLSTDEPSAVVKHFSKENKPRHSHMCYWSLGFDYDF
GHLKITRSDEKYTFIEEFQIKNQGNKRYQRLKWLSSIVVDKEGNASNCSLRNEKSFFF
SRVKSFKDPG"
gene complement(337527..339473)
/gene="CHA4"
/locus_tag="YLR098C"
/gene_synonym="SIL2; SIL3"
/db_xref="GeneID:850787"
mRNA complement(337527..339473)
/gene="CHA4"
/locus_tag="YLR098C"
/gene_synonym="SIL2; SIL3"
/product="Cha4p"
/transcript_id="NM_001181985.1"
/db_xref="GI:296146634"
/db_xref="GeneID:850787"
CDS complement(337527..339473)
/gene="CHA4"
/locus_tag="YLR098C"
/gene_synonym="SIL2; SIL3"
/note="DNA binding transcriptional activator, mediates
serine/threonine activation of the catabolic L-serine
(L-threonine) deaminase (CHA1); Zinc-finger protein with
Zn[2]-Cys[6] fungal-type binuclear cluster domain"
/codon_start=1
/product="Cha4p"
/protein_id="NP_013199.1"
/db_xref="GI:6323127"
/db_xref="SGD:S000004088"
/db_xref="GeneID:850787"
/translation="MMLEPSPPPLTTTVTPSLPSSLKKSVTDNDQNNNNVPRKRKLAC
QNCRRRRRKCNMEKPCSNCIKFRTECVFTQQDLRNKRYSTTYVEALQSQIRSLKEQLQ
ILSSSSSTIASNALSSLKNNSDHGDAPNEKILKYGETAQSALPSSESNDENESDAFTK
KMPSESPPPVGTNSIYPSNSLSIIKKKTDGSTRYQQQQVSLKNLSRSPLILRSLSLFF
KWLYPGHYLFIHRETFLSAFFGDTNTKSYYCSEELVFAIAALGSLISYKSETELFQQS
EVFYQRAKTIVLKKIFQLEDSSLAESSSSSKLAIIQTLLCLAFYDIGSGENPMAWYLS
GLAFRIAHEIGLHLNPEAWSNVYEDELSIMDFEVRSRIYWGCYIADHLIAILFGRSTS
LRLSNSTVPETDELPEIETGIEEYIYDPKVILSTANPLKKLIVLSRITEIFASKIFSP
NETLLQRSEYLAKFNLEVYNWRRDLPPELQWTKRSLMEMTDFNPTIAYVWFHYYIVLI
SYNKPFIYEIKQSRELVEGYVDELYYLLKVWKNKFKTFEKATIYMIYSAILAIQCMKS
NLIKKDRKQDFLNFLSAPTLNYELARKFIENSEDALHNSETMDLLGTLSHGNDFALEY
NFDFTLLNEIDMLIGGNTNDGLSK"
gene complement(339744..340928)
/gene="ICT1"
/locus_tag="YLR099C"
/db_xref="GeneID:850788"
mRNA complement(339744..340928)
/gene="ICT1"
/locus_tag="YLR099C"
/product="lysophosphatidic acid acyltransferase ICT1"
/transcript_id="NM_001181986.1"
/db_xref="GI:296146635"
/db_xref="GeneID:850788"
CDS complement(339744..340928)
/gene="ICT1"
/locus_tag="YLR099C"
/EC_number="3.4.21.-"
/note="Lysophosphatidic acid acyltransferase; responsible
for enhanced phospholipid synthesis during organic solvent
stress; null displays increased sensitivity to Calcofluor
white; highly expressed during organic solvent stress;
ICT1 has a paralog, ECM18, that arose from the whole
genome duplication"
/codon_start=1
/product="lysophosphatidic acid acyltransferase ICT1"
/protein_id="NP_013200.1"
/db_xref="GI:6323128"
/db_xref="SGD:S000004089"
/db_xref="GeneID:850788"
/translation="MWTNTFKWCSKTEKETTTADAKVCASVQGLKALQQQIMDSTTVR
GSVNNTMTPGGINQWHFHNKRANKVCTPTVLIHGYAASSMAFYRTFENLSDNIKDLYA
IDLPANGASEAPALQVNKTKKIKSLRFKHIEDDVVIPVIEKRPPAEDIKSHLEQYESY
FVDRIEQWRKDNKLRKINVVGHSFGGYISFKYALKYPDSIEKLCLISPLGVENSIHAI
THKWEPNTTYPLTFTDPSSRYYTRKLNVPRFIFENQLNVLKWMGPIGSKLCSNYISTA
YVKVPDQIYKDYLLHSFVGKNQTVQPQTIKVFTHLFERNLIARDPIINNVRFLNPATP
VMFMYGEHDWMDKYAGYLTTESMLKNKAKASYVEVPDAGHNLFLDNPQHFASSLVSFL
SK"
gene 341325..341588
/gene="MIM2"
/locus_tag="YLR099W-A"
/db_xref="GeneID:850789"
mRNA 341325..341588
/gene="MIM2"
/locus_tag="YLR099W-A"
/product="Mim2p"
/transcript_id="NM_001184484.1"
/db_xref="GI:296146636"
/db_xref="GeneID:850789"
CDS 341325..341588
/gene="MIM2"
/locus_tag="YLR099W-A"
/note="Mitochondrial protein required for outer membrane
protein import; involved in import of the subset of
proteins with multiple alpha-helical transmembrane
segments, including Ugo1p, Tom20p, and Fzo1p; component of
a large protein complex in the outer membrane that
includes Mim1p; not essential in W303 strain background"
/codon_start=1
/product="Mim2p"
/protein_id="NP_076901.1"
/db_xref="GI:13129179"
/db_xref="SGD:S000007618"
/db_xref="GeneID:850789"
/translation="MADSEDTSVILQGIDTINSVEGLEEDGYLSDEDTSLSNELADAQ
RQWEESLQQLNKLLNWVLLPLLGKYIGRRMAKTLWSRFIEHFV"
gene 341810..342853
/gene="ERG27"
/locus_tag="YLR100W"
/db_xref="GeneID:850790"
mRNA 341810..342853
/gene="ERG27"
/locus_tag="YLR100W"
/product="3-keto-steroid reductase"
/transcript_id="NM_001181987.1"
/db_xref="GI:296146637"
/db_xref="GeneID:850790"
CDS 341810..342853
/gene="ERG27"
/locus_tag="YLR100W"
/EC_number="1.1.1.270"
/note="3-keto sterol reductase, catalyzes the last of
three steps required to remove two C-4 methyl groups from
an intermediate in ergosterol biosynthesis; mutants are
sterol auxotrophs"
/codon_start=1
/product="3-keto-steroid reductase"
/protein_id="NP_013201.1"
/db_xref="GI:6323129"
/db_xref="SGD:S000004090"
/db_xref="GeneID:850790"
/translation="MNRKVAIVTGTNSNLGLNIVFRLIETEDTNVRLTIVVTSRTLPR
VQEVINQIKDFYNKSGRVEDLEIDFDYLLVDFTNMVSVLNAYYDINKKYRAINYLFVN
AAQGIFDGIDWIGAVKEVFTNPLEAVTNPTYKIQLVGVKSKDDMGLIFQANVFGPYYF
ISKILPQLTRGKAYIVWISSIMSDPKYLSLNDIELLKTNASYEGSKRLVDLLHLATYK
DLKKLGINQYVVQPGIFTSHSFSEYLNFFTYFGMLCLFYLARLLGSPWHNIDGYKAAN
APVYVTRLANPNFEKQDVKYGSATSRDGMPYIKTQEIDPTGMSDVFAYIQKKKLEWDE
KLKDQIVETRTPI"
gene complement(342970..343767)
/gene="APC9"
/locus_tag="YLR102C"
/db_xref="GeneID:850792"
mRNA complement(342970..343767)
/gene="APC9"
/locus_tag="YLR102C"
/product="anaphase promoting complex subunit 9"
/transcript_id="NM_001181989.1"
/db_xref="GI:296146638"
/db_xref="GeneID:850792"
CDS complement(342970..343767)
/gene="APC9"
/locus_tag="YLR102C"
/note="Subunit of the Anaphase-Promoting Complex/Cyclosome
(APC/C), which is a ubiquitin-protein ligase required for
degradation of anaphase inhibitors, including mitotic
cyclins, during the metaphase/anaphase transition"
/codon_start=1
/product="anaphase promoting complex subunit 9"
/protein_id="NP_013203.1"
/db_xref="GI:6323131"
/db_xref="SGD:S000004092"
/db_xref="GeneID:850792"
/translation="MNQNGDKNEGKLFQLPSLPPWKTPRFNKANFNNFTTPLRKRSTR
VINDDSMPITGEVLEERTADDLYGINMDVDEVDYLNTLSHIEEEKQYDYSPFCERNTL
RESRIDSFLKAERAAHCLVFHKVGHLDGIDSYRPDIDIMCGEEANKYDSANPEGNGSM
LLESVPGCNKEDLERLSRREFVTNSKPNMRRLDDIINHETNALKSFWNDSGLVNSLQS
HHLHEEYLLLQEELKNVYKIKCHDRVPIESLRDKCRRHYSNEDSSFL"
gene complement(343989..345941)
/gene="CDC45"
/locus_tag="YLR103C"
/gene_synonym="SLD4"
/db_xref="GeneID:850793"
mRNA complement(343989..345941)
/gene="CDC45"
/locus_tag="YLR103C"
/gene_synonym="SLD4"
/product="Cdc45p"
/transcript_id="NM_001181990.1"
/db_xref="GI:296146639"
/db_xref="GeneID:850793"
CDS complement(343989..345941)
/gene="CDC45"
/locus_tag="YLR103C"
/gene_synonym="SLD4"
/note="DNA replication initiation factor; recruited to MCM
pre-RC complexes at replication origins; promotes release
of MCM from Mcm10p, recruits elongation machinery; mutants
in human homolog may cause velocardiofacial and DiGeorge
syndromes"
/codon_start=1
/product="Cdc45p"
/protein_id="NP_013204.1"
/db_xref="GI:6323132"
/db_xref="SGD:S000004093"
/db_xref="GeneID:850793"
/translation="MYYGISQFSEAYNKILRNSSSHSSCQLVIFVSCLNIDALCATKM
LSLLFKKQLVQSQIVPIFGYSELRRHYSQLDDNINSLLLVGFGGVIDLEAFLEIDPQE
YVIDTDEKSGEQSFRRDIYVLDAHRPWNLDNIFGSQIIQCFDDGTVDDTLGEQKEAYY
KLLELDEESGDDELSGDENDNNGGDDEATDADEVTDEDEEDEDETISNKRGNSSIGPN
DLSKRKQRKKQIHEYEGVLEEYYSQGTTVVNSISAQIYSLLSAIGETNLSNLWLNILG
TTSLDIAYAQVYNRLYPLLQDEVKRLTPSSRNSVKTPDTLTLNIQPDYYLFLLRHSSL
YDSFYYSNYVNAKLSLWNENGKKRLHKMFARMGIPLSTAQETWLYMDHSIKRELGIIF
DKNLDRYGLQDIIRDGFVRTLGYRGSISASEFVEALTALLEVGNSTDKDSVKINNDNN
DDTDGEEEEDNSAQKLTNLRKRWVSNFWLSWDALDDRKVELLNRGIQLAQDLQRAIFN
TGVAILEKKLIKHLRIYRLCVLQDGPDLDLYRNPLTLLRLGNWLIECCAESEDKQLLP
MVLASIDENTDTYLVAGLTPRYPRGLDTIHTKKPILNNFSMAFQQITAETDAKVRIDN
FESSIIEIRREDLSPFLEKLTLSGLL"
gene 346585..346980
/gene="LCL2"
/locus_tag="YLR104W"
/db_xref="GeneID:850794"
mRNA 346585..346980
/gene="LCL2"
/locus_tag="YLR104W"
/product="Lcl2p"
/transcript_id="NM_001181991.1"
/db_xref="GI:296146640"
/db_xref="GeneID:850794"
CDS 346585..346980
/gene="LCL2"
/locus_tag="YLR104W"
/note="hypothetical protein; mutant is deficient in
amounts of cell wall mannosylphosphate and has long
chronological lifespan; genetic interactions suggest a
role in ER-associated protein degradation (ERAD)"
/codon_start=1
/product="Lcl2p"
/protein_id="NP_013205.1"
/db_xref="GI:6323133"
/db_xref="SGD:S000004094"
/db_xref="GeneID:850794"
/translation="MSQSRWSIVLIFALFIFGSTGVNAFFNFGHHQQQQQQQQQSYED
QVLNNPCDGYLCPDTLTCVAQQKDCPCPFPKSQLKCVLPDNKFVCISKPATHNEKFRA
IYDDPVKGPKAKNKGFRDCGWVSDAYKNH"
gene complement(347047..348180)
/gene="SEN2"
/locus_tag="YLR105C"
/db_xref="GeneID:850795"
mRNA complement(347047..348180)
/gene="SEN2"
/locus_tag="YLR105C"
/product="Sen2p"
/transcript_id="NM_001181992.1"
/db_xref="GI:296146641"
/db_xref="GeneID:850795"
CDS complement(347047..348180)
/gene="SEN2"
/locus_tag="YLR105C"
/EC_number="3.1.27.9"
/note="Subunit of the tRNA splicing endonuclease, which is
composed of Sen2p, Sen15p, Sen34p, and Sen54p; Sen2p
contains the active site for tRNA 5' splice site cleavage
and has similarity to Sen34p and to Archaeal tRNA splicing
endonuclease"
/codon_start=1
/product="Sen2p"
/protein_id="NP_013206.1"
/db_xref="GI:6323134"
/db_xref="SGD:S000004095"
/db_xref="GeneID:850795"
/translation="MSKGRVNQKRYKYPLPIHPVDDLPELILHNPLSWLYWAYRYYKS
TNALNDKVHVDFIGDTTLHITVQDDKQMLYLWNNGFFGTGQFSRSEPTWKARTEARLG
LNDTPLHNRGGTKSNTETEMTLEKVTQQRRLQRLEFKKERAKLERELLELRKKGGHID
EENILLEKQRESLRKFKLKQTEDVGIVAQQQDISESNLRDEDNNLLDENGDLLPLESL
ELMPVEAMFLTFALPVLDISPACLAGKLFQFDAKYKDIHSFVRSYVIYHHYRSHGWCV
RSGIKFGCDYLLYKRGPPFQHAEFCVMGLDHDVSKDYTWYSSIARVVGGAKKTFVLCY
VERLISEQEAIALWKSNNFTKLFNSFQVGEVLYKRWVPGRNRD"
gene complement(348427..348510)
/locus_tag="snR79"
/db_xref="GeneID:9164937"
ncRNA complement(348427..348510)
/locus_tag="snR79"
/ncRNA_class="snoRNA"
/product="SNR79"
/note="C/D box small nucleolar RNA (snoRNA), guides
2'-O-methylation of small subunit (SSU) rRNA at position
C1007"
/db_xref="SGD:S000007313"
/db_xref="GeneID:9164937"
gene complement(349006..363738)
/gene="MDN1"
/locus_tag="YLR106C"
/gene_synonym="REA1"
/db_xref="GeneID:850796"
mRNA complement(349006..363738)
/gene="MDN1"
/locus_tag="YLR106C"
/gene_synonym="REA1"
/product="Mdn1p"
/transcript_id="NM_001181993.1"
/db_xref="GI:296146642"
/db_xref="GeneID:850796"
CDS complement(349006..363738)
/gene="MDN1"
/locus_tag="YLR106C"
/gene_synonym="REA1"
/note="Huge dynein-related AAA-type ATPase (midasin),
forms extended pre-60S particle with the Rix1 complex
(Rix1p-Ipi1p-Ipi3p); acts in removal of ribosomal
biogenesis factors at successive steps of pre-60S assembly
and export from nucleus"
/codon_start=1
/product="AAA family ATPase midasin"
/protein_id="NP_013207.1"
/db_xref="GI:6323135"
/db_xref="SGD:S000004096"
/db_xref="GeneID:850796"
/translation="MSQDRILLDLDVVNQRLILFNSAFPSDAIEAPFHFSNKESTSEN
LDNLAGTILHSRSITGHVFLYKHIFLEIVARWIKDSKKKDYVLVIEKLASIITIFPVA
MPLIEDYLDKENDHFITILQNPSTQKDSDMFKILLAYYRLLYHNKEVFARFIQPDILY
QLVDLLTKEQENQVVIFLALKVLSLYLDMGEKTLNDMLDTYIKSRDSLLGHFEGDSGI
DYSFLELNEAKRCANFSKLPSVPECFTIEKKSSYFIIEPQDLSTKVASICGVIVPKVH
TIHDKVFYPLTFVPTHKTVSSLRQLGRKIQNSTPIMLIGKAGSGKTFLINELSKYMGC
HDSIVKIHLGEQTDAKLLIGTYTSGDKPGTFEWRAGVLATAVKEGRWVLIEDIDKAPT
DVLSILLSLLEKRELTIPSRGETVKAANGFQLISTVRINEDHQKDSSNKIYNLNMIGM
RIWNVIELEEPSEEDLTHILAQKFPILTNLIPKLIDSYKNVKSIYMNTKFISLNKGAH
TRVVSVRDLIKLCERLDILFKNNGINKPDQLIQSSVYDSIFSEAADCFAGAIGEFKAL
EPIIQAIGESLDIASSRISLFLTQHVPTLENLDDSIKIGRAVLLKEKLNIQKKSMNST
LFAFTNHSLRLMEQISVCIQMTEPVLLVGETGTGKTTVVQQLAKMLAKKLTVINVSQQ
TETGDLLGGYKPVNSKTVAVPIQENFETLFNATFSLKKNEKFHKMLHRCFNKNQWKNV
VKLWNEAYKMAQSILKITNTENENENAKKKKRRLNTHEKKLLLDKWADFNDSVKKFEA
QSSSIENSFVFNFVEGSLVKTIRAGEWLLLDEVNLATADTLESISDLLTEPDSRSILL
SEKGDAEPIKAHPDFRIFACMNPATDVGKRDLPMGIRSRFTEIYVHSPERDITDLLSI
IDKYIGKYSVSDEWVGNDIAELYLEAKKLSDNNTIVDGSNQKPHFSIRTLTRTLLYVT
DIIHIYGLRRSLYDGFCMSFLTLLDQKSEAILKPVIEKFTLGRLKNVKSIMSQTPPSP
GPDYVQFKHYWMKKGPNTIQEQAHYIITPFVEKNMMNLVRATSGKRFPVLIQGPTSSG
KTSMIKYLADITGHKFVRINNHEHTDLQEYLGTYVTDDTGKLSFKEGVLVEALRKGYW
IVLDELNLAPTDVLEALNRLLDDNRELFIPETQEVVHPHPDFLLFATQNPPGIYGGRK
ILSRAFRNRFLELHFDDIPQDELEIILRERCQIAPSYAKKIVEVYRQLSIERSASRLF
EQKNSFATLRDLFRWALRDAVGYEQLAASGYMLLAERCRTPQEKVTVKKTLEKVMKVK
LDMDQYYASLEDKSLEAIGSVTWTKGMRRLSVLVSSCLKNKEPVLLVGETGCGKTTIC
QLLAQFMGRELITLNAHQNTETGDILGAQRPVRNRSEIQYKLIKSLKTALNIANDQDV
DLKELLQLYSKSDNKNIAEDVQLEIQKLRDSLNVLFEWSDGPLIQAMRTGNFFLLDEI
SLADDSVLERLNSVLEPERSLLLAEQGSSDSLVTASENFQFFATMNPGGDYGKKELSP
ALRNRFTEIWVPSMEDFNDVNMIVSSRLLEDLKDLANPIVKFSEWFGKKLGGGNATSG
VISLRDILAWVEFINKVFPKIQNKSTALIQGASMVFIDALGTNNTAYLAENENDLKSL
RTECIIQLLKLCGDDLELQQIETNEIIVTQDELQVGMFKIPRFPDAQSSSFNLTAPTT
ASNLVRVVRAMQVHKPILLEGSPGVGKTSLITALANITGNKLTRINLSEQTDLVDLFG
ADAPGERSGEFLWHDAPFLRAMKKGEWVLLDEMNLASQSVLEGLNACLDHRGEAYIPE
LDISFSCHPNFLVFAAQNPQYQGGGRKGLPKSFVNRFSVVFIDMLTSDDLLLIAKHLY
PSIEPDIIAKMIKLMSTLEDQVCKRKLWGNSGSPWEFNLRDTLRWLKLLNQYSICEDV
DVFDFVDIIVKQRFRTISDKNKAQLLIEDIFGKFSTKENFFKLTEDYVQINNEVALRN
PHYRYPITQNLFPLECNVAVYESVLKAINNNWPLVLVGPSNSGKTETIRFLASILGPR
VDVFSMNSDIDSMDILGGYEQVDLTRQISYITEELTNIVREIISMNMKLSPNATAIME
GLNLLKYLLNNIVTPEKFQDFRNRFNRFFSHLEGHPLLKTMSMNIEKMTEIITKEASV
KFEWFDGMLVKAVEKGHWLILDNANLCSPSVLDRLNSLLEIDGSLLINECSQEDGQPR
VLKPHPNFRLFLTMDPKYGELSRAMRNRGVEIYIDELHSRSTAFDRLTLGFELGENID
FVSIDDGIKKIKLNEPDMSIPLKHYVPSYLSRPCIFAQVHDILLLSDEEPIEESLAAV
IPISHLGEVGKWANNVLNCTEYSEKKIAERLYVFITFLTDMGVLEKINNLYKPANLKF
QKALGLHDKQLTEETVSLTLNEYVLPTVSKYSDKIKSPESLYLLSSLRLLLNSLNALK
LINEKSTHGKIDELTYIELSAAAFNGRHLKNIPRIPIFCILYNILTVMSENLKTESLF
CGSNQYQYYWDLLVIVIAALETAVTKDEARLRVYKELIDSWIASVKSKSDIEITPFLN
INLEFTDVLQLSRGHSITLLWDIFRKNYPTTSNSWLAFEKLINLSEKFDKVRLLQFSE
SYNSIKDLMDVFRLLNDDVLNNKLSEFNLLLSKLEDGINELELISNKFLNKRKHYFAD
EFDNLIRYTFSVDTAELIKELAPASSLATQKLTKLITNKYNYPPIFDVLWTEKNAKLT
SFTSTIFSSQFLEDVVRKSNNLKSFSGNQIKQSISDAELLLSSTIKCSPNLLKSQMEY
YKNMLLSWLRKVIDIHVGGDCLKLTLKELCSLIEEKTASETRVTFAEYIFPALDLAES
SKSLEELGEAWITFGTGLLLLFVPDSPYDPAIHDYVLYDLFLKTKTFSQNLMKSWRNV
RKVISGDEEIFTEKLINTISDDDAPQSPRVYRTGMSIDSLFDEWMAFLSSTMSSRQIK
ELVSSYKCNSDQSDRRLEMLQQNSAHFLNRLESGYSKFADLNDILAGYIYSINFGFDL
LKLQKSKDRASFQISPLWSMDPINISCAENVLSAYHELSRFFKKGDMEDTSIEKVLMY
FLTLFKFHKRDTNLLEIFEAALYTLYSRWSVRRFRQEQEENEKSNMFKFNDNSDDYEA
DFRKLFPDYEDTALVTNEKDISSPENLDDIYFKLADTYISVFDKDHDANFSSELKSGA
IITTILSEDLKNTRIEELKSGSLSAVINTLDAETQSFKNTEVFGNIDFYHDFSIPEFQ
KAGDIIETVLKSVLKLLKQWPEHATLKELYRVSQEFLNYPIKTPLARQLQKIEQIYTY
LAEWEKYASSEVSLNNTVKLITDLIVSWRKLELRTWKGLFNSEDAKTRKSIGKWWFYL
YESIVISNFVSEKKETAPNATLLVSSLNLFFSKSTLGEFNARLDLVKAFYKHIQLIGL
RSSKIAGLLHNTIKFYYQFKPLIDERITNGKKSLEKEIDDIILLASWKDVNVDALKQS
SRKSHNNLYKIVRKYRDLLNGDAKTIIEAGLLYSNENKLKLPTLKQHFYEDPNLEASK
NLVKEISTWSMRAAPLRNIDTVASNMDSYLEKISSQEFPNFADLASDFYAEAERLRKE
TPNVYTKENKKRLAYLKTQKSKLLGDALKELRRIGLKVNFREDIQKVQSSTTTILANI
APFNNEYLNSSDAFFFKILDLLPKLRSAASNPSDDIPVAAIERGMALAQSLMFSLITV
RHPLSEFTNDYCKINGMMLDLEHFTCLKGDIVHSSLKANVDNVRLFEKWLPSLLDYAA
QTLSVISKYSATSEQQKILLDAKSTLSSFFVHFNSSRIFDSSFIESYSRFELFINELL
KKLENAKETGNAFVFDIIIEWIKANKGGPIKKEQKRGPSVEDVEQAFRRTFTSIILSF
QKVIGDGIESISETDDNWLSASFKKVMVNVKLLRSSVVSKNIETALSLLKDFDFTTTE
SIYVKSVISFTLPVITRYYNAMTVVLERSRIYYTNTSRGMYILSTILHSLAKNGFCSP
QPPSEEVDDKNLQEGTGLGDGEGAQNNNKDVEQDEDLTEDAQNENKEQQDKDERDDEN
EDDAVEMEGDMAGELEDLSNGEENDDEDTDSEEEELDEEIDDLNEDDPNAIDDKMWDD
KASDNSKEKDTDQNLDGKNQEEDVQAAENDEQQRDNKEGGDEDPNAPEDGDEEIENDE
NAEEENDVGEQEDEVKDEEGEDLEANVPEIETLDLPEDMNLDSEHEESDEDVDMSDGM
PDDLNKEEVGNEDEEVKQESGIESDNENDEPGPEEDAGETETALDEEEGAEEDVDMTN
DEGKEDEENGPEEQAMSDEEELKQDAAMEENKEKGGEQNTEGLDGVEEKADTEDIDQE
AAVQQDSGSKGAGADATDTQEQDDVGGSGTTQNTYEEDQEDVTKNNEESREEATAALK
QLGDSMKEYHRRRQDIKEAQTNGEEDENLEKNNERPDEFEHVEGANTETDTQALGSAT
QDQLQTIDEDMAIDDDREEQEVDQKELVEDADDEKMDIDEEEMLSDIDAHDANNDVDS
KKSGFIGKRKSEEDFENELSNEHFSADQEDDSEIQSLIENIEDNPPDASASLTPERSL
EESRELWHKSEISTADLVSRLGEQLRLILEPTLATKLKGDYKTGKRLNMKRIIPYIAS
QFRKDKIWLRRTKPSKRQYQIMIALDDSKSMSESKCVKLAFDSLCLVSKTLTQLEAGG
LSIVKFGENIKEVHSFDQQFSNESGARAFQWFGFQETKTDVKKLVAESTKIFERARAM
VHNDQWQLEIVISDGICEDHETIQKLVRRARENKIMLVFVIIDGITSNESILDMSQVN
YIPDQYGNPQLKITKYLDTFPFEFYVVVHDISELPEMLSLILRQYFTDLASS"
gene 364116..365330
/gene="REX3"
/locus_tag="YLR107W"
/db_xref="GeneID:850797"
mRNA 364116..365330
/gene="REX3"
/locus_tag="YLR107W"
/product="Rex3p"
/transcript_id="NM_001181994.1"
/db_xref="GI:296146643"
/db_xref="GeneID:850797"
CDS 364116..365330
/gene="REX3"
/locus_tag="YLR107W"
/EC_number="3.1.-.-"
/note="RNA exonuclease; required for maturation of the RNA
component of RNase MRP; functions redundantly with Rnh70p
and Rex2p in processing of U5 snRNA and RNase P RNA;
member of RNase D family of exonucleases"
/codon_start=1
/product="Rex3p"
/protein_id="NP_013208.1"
/db_xref="GI:6323136"
/db_xref="SGD:S000004097"
/db_xref="GeneID:850797"
/translation="MGSLLRPVDLVNQPLGFQERYKILQKLFKQLQKAYAHTKGTNID
LERLATRLEVHVAKNSLSGQSYKFNMSILLRDVLKYKGDLSKIKINGRPLKGAKPHLS
SIGNANSITTKSKAMEALKALILDSKVLEKNGYIVKEMQNKTNDDNSTQLYAPCLRCS
SNFKKTDIMEKTLCRYHPLKRIYNRDTKNHQYPCCGETTDSVSFLRLGCKTFFHHVFR
GESYDELCKISKFSSTDDIDGVENVLSLDCEMAFTSLGYEMIRLTIVDFFTGKTLFDH
VIQPIGDIVDLNSDFSGVHEIDRTNCPTYKEALDVFLSENLINKNSILIGHGLENDLN
VMRLFHNKVIDTAILYSRTKFKVSLKNLAFEVLSRKIQNGEHDSSQDAIATMDVVKVK
IGISPSQNKWEK"
LTR complement(365810..366144)
/note="Ty1 LTR"
/db_xref="SGD:S000007067"
gene 366235..366346
/locus_tag="snR6"
/db_xref="GeneID:9164922"
ncRNA 366235..366346
/locus_tag="snR6"
/ncRNA_class="snRNA"
/product="SNR6"
/note="U6 spliceosomal RNA (U6 snRNA), interacts with U4;
homology to U6 snRNA, interacts with snr14"
/db_xref="SGD:S000006494"
/db_xref="GeneID:9164922"
gene complement(366667..368124)
/locus_tag="YLR108C"
/db_xref="GeneID:850798"
mRNA complement(366667..368124)
/locus_tag="YLR108C"
/product="hypothetical protein"
/transcript_id="NM_001181995.1"
/db_xref="GI:296146644"
/db_xref="GeneID:850798"
CDS complement(366667..368124)
/locus_tag="YLR108C"
/note="hypothetical protein; green fluorescent protein
(GFP)-fusion protein localizes to the nucleus; YLR108C is
not an esssential gene; protein abundance increases in
response to DNA replication stress"
/codon_start=1
/product="hypothetical protein"
/protein_id="NP_013209.1"
/db_xref="GI:6323137"
/db_xref="SGD:S000004098"
/db_xref="GeneID:850798"
/translation="MSGQKGEIVVYTKELETTPELLPNHEVFKIRIGQKLFEISGATL
NSDAPNFFTQFFNTHDKNTILFVDRSEDVFIIIYRHLQGYFPDIKNEVQFTCLFADAL
YFQLPKLVKLIKEYDYHFTNIGGVPFKVPKSLFHEEGNRLNYFETISRISYEEIEKWE
SNKKPGFPPLLPPSYIARSPEFFRDILSLLGGSKLELSEERTASLIKECRYYRLNRLE
QELVRAKIIYNPLTNCQEVCIALDSVSKKGVTIERLTSLHTGNQSLAVSSCLNGTEGE
KAATGFHKTETDSGNNDEYEPPTKKVKHCIERHWSMLKYQRPYIDTVSHDLIFQLHSN
QCKIIFNKKNKTVHVDLSREAAVLFENKFSDVLLENPDFKIDLSEYKVKLRDSQMQVE
SHLIIPACVSICDLTVNGAKCCNIFSLVNDSKCKGRVLDCTNLKVLNCVHGLKLHLSK
SMWKLGTNNGRIILVAVKAETFSGTKEYCKMIDFL"
gene 368781..369311
/gene="AHP1"
/locus_tag="YLR109W"
/db_xref="GeneID:850799"
mRNA 368781..369311
/gene="AHP1"
/locus_tag="YLR109W"
/product="Ahp1p"
/transcript_id="NM_001181996.1"
/db_xref="GI:296146645"
/db_xref="GeneID:850799"
CDS 368781..369311
/gene="AHP1"
/locus_tag="YLR109W"
/EC_number="1.11.1.15"
/note="Thiol-specific peroxiredoxin, reduces
hydroperoxides to protect against oxidative damage;
function in vivo requires covalent conjugation to Urm1p"
/codon_start=1
/product="Ahp1p"
/protein_id="NP_013210.1"
/db_xref="GI:6323138"
/db_xref="SGD:S000004099"
/db_xref="GeneID:850799"
/translation="MSDLVNKKFPAGDYKFQYIAISQSDADSESCKMPQTVEWSKLIS
ENKKVIITGAPAAFSPTCTVSHIPGYINYLDELVKEKEVDQVIVVTVDNPFANQAWAK
SLGVKDTTHIKFASDPGCAFTKSIGFELAVGDGVYWSGRWAMVVENGIVTYAAKETNP
GTDVTVSSVESVLAHL"
gene complement(369697..370098)
/gene="CCW12"
/locus_tag="YLR110C"
/db_xref="GeneID:850800"
mRNA complement(369697..370098)
/gene="CCW12"
/locus_tag="YLR110C"
/product="Ccw12p"
/transcript_id="NM_001181997.1"
/db_xref="GI:296146646"
/db_xref="GeneID:850800"
CDS complement(369697..370098)
/gene="CCW12"
/locus_tag="YLR110C"
/note="Cell wall mannoprotein; plays a role in maintenance
of newly synthesized areas of cell wall; localizes to
periphery of small buds, septum region of larger buds, and
shmoo tip; CCW12 has a paralog, YDR134C, that arose from
the whole genome duplication"
/codon_start=1
/product="Ccw12p"
/protein_id="NP_013211.1"
/db_xref="GI:6323139"
/db_xref="SGD:S000004100"
/db_xref="GeneID:850800"
/translation="MQFSTVASIAAVAAVASAAANVTTATVSQESTTLVTITSCEDHV
CSETVSPALVSTATVTVDDVITQYTTWCPLTTEAPKNGTSTAAPVTSTEAPKNTTSAA
PTHSVTSYTGAAAKALPAAGALLAGAAALLL"
gene 371620..372927
/gene="HOG1"
/locus_tag="YLR113W"
/gene_synonym="SSK3"
/db_xref="GeneID:850803"
mRNA 371620..372927
/gene="HOG1"
/locus_tag="YLR113W"
/gene_synonym="SSK3"
/product="Hog1p"
/transcript_id="NM_001182000.1"
/db_xref="GI:296146647"
/db_xref="GeneID:850803"
CDS 371620..372927
/gene="HOG1"
/locus_tag="YLR113W"
/gene_synonym="SSK3"
/EC_number="2.7.11.24"
/note="Mitogen-activated protein kinase involved in
osmoregulation; controls global reallocation of RNA Pol II
in response to osmotic shock; acts via three independent
osmosensors; mitophagy-specific regulator; mediates the
recruitment and activation of RNA Pol II at
Hot1p-dependent promoters; localization regulated by Ptp2p
and Ptp3p; protein abundance increases in response to DNA
replication stress"
/codon_start=1
/product="Hog1p"
/protein_id="NP_013214.1"
/db_xref="GI:6323142"
/db_xref="SGD:S000004103"
/db_xref="GeneID:850803"
/translation="MTTNEEFIRTQIFGTVFEITNRYNDLNPVGMGAFGLVCSATDTL
TSQPVAIKKIMKPFSTAVLAKRTYRELKLLKHLRHENLICLQDIFLSPLEDIYFVTEL
QGTDLHRLLQTRPLEKQFVQYFLYQILRGLKYVHSAGVIHRDLKPSNILINENCDLKI
CDFGLARIQDPQMTGYVSTRYYRAPEIMLTWQKYDVEVDIWSAGCIFAEMIEGKPLFP
GKDHVHQFSIITDLLGSPPKDVINTICSENTLKFVTSLPHRDPIPFSERFKTVEPDAV
DLLEKMLVFDPKKRITAADALAHPYSAPYHDPTDEPVADAKFDWHFNDADLPVDTWRV
MMYSEILDFHKIGGSDGQIDISATFDDQVAAATAAAAQAQAQAQAQVQLNMAAHSHNG
AGTTGNDHSDIAGGNKVSDHVAANDTITDYGNQAIQYANEFQQ"
rep_origin 373156..373399
/note="ARS1213;
Autonomously Replicating Sequence"
/db_xref="SGD:S000118473"
LTR 373999..374338
/note="Ty3 LTR"
/db_xref="SGD:S000007095"
gene 374355..374427
/locus_tag="tR(ACG)L"
/db_xref="GeneID:850804"
tRNA 374355..374427
/locus_tag="tR(ACG)L"
/product="tRNA-Arg"
/note="Arginine tRNA (tRNA-Arg), predicted by tRNAscan-SE
analysis; one of 6 nuclear tRNA genes containing the
tDNA-anticodon ACG (converted to ICG in the mature tRNA),
decodes CGU, CGC, and probably CGA codons into arginine,
one of 19 nuclear tRNAs for arginine"
/db_xref="SGD:S000006704"
/db_xref="GeneID:850804"
gene complement(374944..377238)
/gene="AVL9"
/locus_tag="YLR114C"
/db_xref="GeneID:850805"
mRNA complement(374944..377238)
/gene="AVL9"
/locus_tag="YLR114C"
/product="Avl9p"
/transcript_id="NM_001182001.1"
/db_xref="GI:296146648"
/db_xref="GeneID:850805"
CDS complement(374944..377238)
/gene="AVL9"
/locus_tag="YLR114C"
/note="Conserved protein involved in exocytic transport
from the Golgi; mutation is synthetically lethal with apl2
vps1 double mutation; member of a protein superfamily with
orthologs in diverse organisms; relocalizes from bud neck
to cytoplasm upon DNA replication stress"
/codon_start=1
/product="Avl9p"
/protein_id="NP_013215.1"
/db_xref="GI:6323143"
/db_xref="SGD:S000004104"
/db_xref="GeneID:850805"
/translation="MDEHEEAVIFGICLVDFHHKRGPEIEYWYGLPEGTQSAELWPNL
PFQALPDGSHSFEETFTYFTLLYDERRQRSPPNGATDLSDDSINDNTTLFAISCSRQI
KSDELVTKDKDVTRSTVQKAIVVISRQPIFGQIKDKLSIVTNAFFLQHDFGDRKIIQS
LYENLKSIYTPASLVRNAENRLYIGLCLRKILHDFKRNALVLLKAIMLEKKIIVYGND
VEALCNLQFGLISLIPDLMSNLQDSGSPQLFQDISKLNVVDSFKSSNRESVLRFLGFP
LPIFEKGGLFSPYTPLQQMNDIRSERTLFFMIGSSNTLLAEQKEELCHIFVNTDNSTV
DILDKTLNPVLQLSSHDKKWIESISGIVSDTWNENDDETPKNSQFEGSEDFIRWQFED
YLTGLLSSVKLSDYLDLHKENDQALKTIPEDMLNSNPVHLFNLNWVQSWKETQNFLIF
NSRTDDRLFDLFPPKHIYNGADTLSLLQQRFLATFHNLKRSSSNSSSNKNGHQSEEDI
KDQESIESKKSVSQISVNPGKNTDKPAANLWNSWKEYFNKPKNTANEDVTESTEDLKN
RSKTSNAIQKAMMGLGLHYKPDAETDQQSEEVGNSEDNEDDDTDEDSEDDDDDGGDDD
DSEDDDDDDDGEGDENGDDGEGDENGDDGEGDENGDKEDSQDFSNGFTDVTNINTDHD
KENEQNFEGNAENFNEDETVADKDIEGGPESNKNSDSKTDIYENDRNVEDSSKTRNTV
KKSNEEGGANDAAIGNCVQDEEKL"
gene 377985..380564
/gene="CFT2"
/locus_tag="YLR115W"
/gene_synonym="YDH1"
/db_xref="GeneID:850806"
mRNA 377985..380564
/gene="CFT2"
/locus_tag="YLR115W"
/gene_synonym="YDH1"
/product="Cft2p"
/transcript_id="NM_001182002.1"
/db_xref="GI:296146649"
/db_xref="GeneID:850806"
CDS 377985..380564
/gene="CFT2"
/locus_tag="YLR115W"
/gene_synonym="YDH1"
/note="Subunit of the mRNA cleavage and polyadenlylation
factor (CPF); required for pre-mRNA cleavage,
polyadenylation and poly(A) site recognition, 43%
similarity with the mammalian CPSF-100 protein."
/codon_start=1
/product="Cft2p"
/protein_id="NP_013216.1"
/db_xref="GI:6323144"
/db_xref="SGD:S000004105"
/db_xref="GeneID:850806"
/translation="MTYKYNCCDDGSGTTVGSVVRFDNVTLLIDPGWNPSKVSYEQCI
KYWEKVIPEIDVIILSQPTIECLGAHSLLYYNFTSHFISRIQVYATLPVINLGRVSTI
DSYASAGVIGPYDTNKLDLEDIEISFDHIVPLKYSQLVDLRSRYDGLTLLAYNAGVCP
GGSIWCISTYSEKLVYAKRWNHTRDNILNAASILDATGKPLSTLMRPSAIITTLDRFG
SSQPFKKRSKIFKDTLKKGLSSDGSVIIPVDMSGKFLDLFTQVHELLFESTKINAHTQ
VPVLILSYARGRTLTYAKSMLEWLSPSLLKTWENRNNTSPFEIGSRIKIIAPNELSKY
PGSKICFVSEVGALINEVIIKVGNSEKTTLILTKPSFECASSLDKILEIVEQDERNWK
TFPEDGKSFLCDNYISIDTIKEEPLSKEETEAFKVQLKEKKRDRNKKILLVKRESKKL
ANGNAIIDDTNGERAMRNQDILVENVNGVPPIDHIMGGDEDDDEEEENDNLLNLLKDN
SEKSAAKKNTEVPVDIIIQPSAASKHKMFPFNPAKIKKDDYGTVVDFTMFLPDDSDNV
NQNSRKRPLKDGAKTTSPVNEEDNKNEEEDGYNMSDPISKRSKHRASRYSGFSGTGEA
ENFDNLDYLKIDKTLSKRTISTVNVQLKCSVVILNLQSLVDQRSASIIWPSLKSRKIV
LSAPKQIQNEEITAKLIKKNIEVVNMPLNKIVEFSTTIKTLDISIDSNLDNLLKWQRI
SDSYTVATVVGRLVKESLPQVNNHQKTASRSKLVLKPLHGSSRSHKTGALSIGDVRLA
QLKKLLTEKNYIAEFKGEGTLVINEKVAVRKINDAETIIDGTPSELFDTVKKLVTDML
AKI"
gene 380822..382252
/gene="MSL5"
/locus_tag="YLR116W"
/db_xref="GeneID:850807"
mRNA 380822..382252
/gene="MSL5"
/locus_tag="YLR116W"
/product="Msl5p"
/transcript_id="NM_001182003.1"
/db_xref="GI:296146650"
/db_xref="GeneID:850807"
CDS 380822..382252
/gene="MSL5"
/locus_tag="YLR116W"
/note="Component of the commitment complex, which defines
the first step in the splicing pathway; essential protein
that interacts with Mud2p and Prp40p, forming a bridge
between the intron ends; also involved in nuclear
retention of pre-mRNA"
/codon_start=1
/product="Msl5p"
/protein_id="NP_013217.1"
/db_xref="GI:6323145"
/db_xref="SGD:S000004106"
/db_xref="GeneID:850807"
/translation="MSFRRINSRYFENRKGSSMEEKKAKVPPNVNLSLWRKNTVESDV
HRFNSLPSKISGALTREQIYSYQVMFRIQEITIKLRTNDFVPPSRKNRSPSPPPVYDA
QGKRTNTREQRYRKKLEDERIKLVEIALKTIPYFVPPDDYKRPTKFQDKYYIPVDQYP
DVNFVGLLLGPRGRTLRKLQEDSNCKIAIRGRGSVKEGKNASDLPPGAMNFEDPLHCL
IIADSEDKIQKGIKVCQNIVIKAVTSPEGQNDLKRGQLRELAELNGTLREDNRPCPIC
GLKDHKRYDCPNRKIPNIQGIVCKICGQTGHFSRDCNSSSQRMSRFDRNATVNNSAPI
QSNDVHYNSNTHPIQAPKRSRYDNNSTEPPLKFPASSRYAPSPSPPASHISRQAQNVT
PTPPPGLTSSSFSSGVPGIAPPPLQSPPESEQPKFSLPPPPGMTTVQSSIAPPPGLSG
PPGFSNNMGNDINKPTPPGLQGPPGL"
gene complement(382471..384534)
/gene="CLF1"
/locus_tag="YLR117C"
/gene_synonym="NTC77; SYF3"
/db_xref="GeneID:850808"
mRNA complement(382471..384534)
/gene="CLF1"
/locus_tag="YLR117C"
/gene_synonym="NTC77; SYF3"
/product="Clf1p"
/transcript_id="NM_001182004.1"
/db_xref="GI:296146651"
/db_xref="GeneID:850808"
CDS complement(382471..384534)
/gene="CLF1"
/locus_tag="YLR117C"
/gene_synonym="NTC77; SYF3"
/note="Member of the NineTeen Complex (NTC) that contains
Prp19p and stabilizes U6 snRNA in catalytic forms of the
spliceosome containing U2, U5, and U6 snRNAs; homolog of
Drosophila crooked neck protein; interacts with U1 snRNP
proteins"
/codon_start=1
/product="Clf1p"
/protein_id="NP_013218.1"
/db_xref="GI:6323146"
/db_xref="SGD:S000004107"
/db_xref="GeneID:850808"
/translation="MDTLEPTAVDTHVSAEQILRDVYKKGQKARGSTNIDILDLEELR
EYQRRKRTEYEGYLKRNRLDMGQWIRYAQFEIEQHDMRRARSIFERALLVDSSFIPLW
IRYIDAELKVKCINHARNLMNRAISTLPRVDKLWYKYLIVEESLNNVEIVRSLYTKWC
SLEPGVNAWNSFVDFEIRQKNWNGVREIYSKYVMAHPQMQTWLKWVRFENRHGNTEFT
RSVYSLAIDTVANLQNLQIWSDMEVAKLVNSFAHWEAAQQEYERSSALYQIAIEKWPS
NQLLKAGLLDFEKQFGDINSIEETISYKRKMEYETILSNNAYDYDTWWLYLDLISESF
PKQIMQTFEKAIVDSRPKELSKNVQWKRYIYLWMRYICYVELELENSLLEEELFQRLI
DDIIPHKHFTFSKIWLMYAKFLIRHDDVPKARKILGKAIGLCPKAKTFKGYIELEVKL
KEFDRVRKIYEKFIEFQPSDLQIWSQYGELEENLGDWDRVRGIYTIALDENSDFLTKE
AKIVLLQKYITFETESQEFEKARKLYRRYLELNQYSPQSWIEFAMYQTSTPTEQQLLD
LAKLQSENVDEDIEFEITDENKLEARKVFEEAIVFFKEKDDKQGRLSILEALKDYEET
YGTELDQETVKKRFPKVIKKVRLQNGVEEEFVDYIFPDDIDDDKPKPSKFLELAKKWK
QEQAL"
rep_origin 384534..384725
/note="ARS1214;
Putative replication origin, identified in multiple array
studies, not yet confirmed by plasmid-based assay"
/db_xref="SGD:S000130182"
gene complement(384725..385408)
/locus_tag="YLR118C"
/gene_synonym="APT1"
/db_xref="GeneID:850809"
mRNA complement(384725..385408)
/locus_tag="YLR118C"
/gene_synonym="APT1"
/product="palmitoyl-(protein) hydrolase"
/transcript_id="NM_001182005.1"
/db_xref="GI:296146652"
/db_xref="GeneID:850809"
CDS complement(384725..385408)
/locus_tag="YLR118C"
/gene_synonym="APT1"
/EC_number="3.1.2.-"
/note="Acyl-protein thioesterase responsible for
depalmitoylation of Gpa1p; green fluorescent protein
(GFP)-fusion protein localizes to both the cytoplasm and
nucleus and is induced in response to the DNA-damaging
agent MMS"
/codon_start=1
/product="palmitoyl-(protein) hydrolase"
/protein_id="NP_013219.1"
/db_xref="GI:6323147"
/db_xref="SGD:S000004108"
/db_xref="GeneID:850809"
/translation="MNGLRVAAKIQPARQTIIFLHGLGDTGSGWGFLAQYLQQRDPAA
FQHTNFVFPNAPELHVTANGGALMPAWFDILEWDPSFSKVDSDGFMNSLNSIEKTVKQ
EIDKGIKPEQIIIGGFSQGAALALATSVTLPWKIGGIVALSGFCSIPGILKQHKNGIN
VKTPIFHGHGDMDPVVPIGLGIKAKQFYQDSCEIQNYEFKVYKGMAHSTVPDELEDLA
SFIKKSLSS"
gene 385534..386175
/gene="SRN2"
/locus_tag="YLR119W"
/gene_synonym="SRN10; VPL16; VPS37"
/db_xref="GeneID:850810"
mRNA 385534..386175
/gene="SRN2"
/locus_tag="YLR119W"
/gene_synonym="SRN10; VPL16; VPS37"
/product="Srn2p"
/transcript_id="NM_001182006.1"
/db_xref="GI:296146653"
/db_xref="GeneID:850810"
CDS 385534..386175
/gene="SRN2"
/locus_tag="YLR119W"
/gene_synonym="SRN10; VPL16; VPS37"
/note="Component of the ESCRT-I complex, which is involved
in ubiquitin-dependent sorting of proteins into the
endosome; suppressor of rna1-1 mutation; may be involved
in RNA export from nucleus"
/codon_start=1
/product="Srn2p"
/protein_id="NP_013220.1"
/db_xref="GI:6323148"
/db_xref="SGD:S000004109"
/db_xref="GeneID:850810"
/translation="MKVKATKLRIKQRRKNKGLNISRLDIIRAEMDVVPSPGLPEKVN
EKSKNIPLPEGINLLSSKEIIDLIQTHRHQLELYVTKFNPLTDFAGKIHAFRDQFKQL
EENFEDLHEQKDKVQALLENCRILESKYVASWQDYHSEFSKKYGDIALKKKLEQNTKK
LDEESSQLETTTRSIDSADDLDQFIKNYLDIRTQYHLRREKLATWDKQGNLKY"
gene complement(386511..388220)
/gene="YPS1"
/locus_tag="YLR120C"
/gene_synonym="YAP3"
/db_xref="GeneID:850811"
mRNA complement(386511..388220)
/gene="YPS1"
/locus_tag="YLR120C"
/gene_synonym="YAP3"
/product="Yps1p"
/transcript_id="NM_001182007.1"
/db_xref="GI:296146654"
/db_xref="GeneID:850811"
CDS complement(386511..388220)
/gene="YPS1"
/locus_tag="YLR120C"
/gene_synonym="YAP3"
/EC_number="3.4.23.41"
/note="Aspartic protease, member of the yapsin family of
proteases involved in cell wall growth and maintenance;
attached to the plasma membrane via a
glycosylphosphatidylinositol (GPI) anchor"
/codon_start=1
/product="Yps1p"
/protein_id="NP_013221.1"
/db_xref="GI:6323149"
/db_xref="SGD:S000004110"
/db_xref="GeneID:850811"
/translation="MKLKTVRSAVLSSLFASQVLGKIIPAANKRDDDSNSKFVKLPFH
KLYGDSLENVGSDKKPEVRLLKRADGYEEIIITNQQSFYSVDLEVGTPPQNVTVLVDT
GSSDLWIMGSDNPYCSSNSMGSSRRRVIDKRDDSSSGGSLINDINPFGWLTGTGSAIG
PTATGLGGGSGTATQSVPASEATMDCQQYGTFSTSGSSTFRSNNTYFSISYGDGTFAS
GTFGTDVLDLSDLNVTGLSFAVANETNSTMGVLGIGLPELEVTYSGSTASHSGKAYKY
DNFPIVLKNSGAIKSNTYSLYLNDSDAMHGTILFGAVDHSKYTGTLYTIPIVNTLSAS
GFSSPIQFDVTINGIGISDSGSSNKTLTTTKIPALLDSGTTLTYLPQTVVSMIATELG
AQYSSRIGYYVLDCPSDDSMEIVFDFGGFHINAPLSSFILSTGTTCLLGIIPTSDDTG
TILGDSFLTNAYVVYDLENLEISMAQARYNTTSENIEIITSSVPSAVKAPGYTNTWST
SASIVTGGNIFTVNSSQTASFSGNLTTSTASATSTSSKRNVGDHIVPSLPLTLISLLF
AFI"
gene complement(388744..390270)
/gene="YPS3"
/locus_tag="YLR121C"
/gene_synonym="YPS4"
/db_xref="GeneID:850812"
mRNA complement(388744..390270)
/gene="YPS3"
/locus_tag="YLR121C"
/gene_synonym="YPS4"
/product="Yps3p"
/transcript_id="NM_001182008.1"
/db_xref="GI:296146655"
/db_xref="GeneID:850812"
CDS complement(388744..390270)
/gene="YPS3"
/locus_tag="YLR121C"
/gene_synonym="YPS4"
/EC_number="3.4.23.-"
/note="Aspartic protease, member of the yapsin family of
proteases involved in cell wall growth and maintenance;
attached to the plasma membrane via a
glycosylphosphatidylinositol (GPI) anchor"
/codon_start=1
/product="Yps3p"
/protein_id="NP_013222.1"
/db_xref="GI:6323150"
/db_xref="SGD:S000004111"
/db_xref="GeneID:850812"
/translation="MKLQLAAVATLAVLTSPAFGRVLPDGKYVKIPFTKKKNGDNGEL
SKRSNGHEKFVLANEQSFYSVELAIGTPSQNLTVLLDTGSADLWVPGKGNPYCGSVMD
CDQYGVFDKTKSSTFKANKSSPFYAAYGDGTYAEGAFGQDKLKYNELDLSGLSFAVAN
ESNSTFGVLGIGLSTLEVTYSGKVAIMDKRSYEYDNFPLFLKHSGAIDATAYSLFLND
ESQSSGSILFGAVDHSKYEGQLYTIPLVNLYKSQGYQHPVAFDVTLQGLGLQTDKRNI
TLTTTKLPALLDSGTTLTYLPSQAVALLAKSLNASYSKTLGYYEYTCPSSDNKTSVAF
DFGGFRINAPLSDFTMQTSVGTCVLAIIPQAGNATAILGDSFLRNAYVVYDLDNYEIS
LAQAKYGTGKENVEVIKSTVPSAIRAPSYNNTWSNYASATSGGNIFTTVRTFNGTSTA
TTTRSTTTKKTNSTTTAKSTHKSKRALQRAATNSASSIRSTLGLLLVPSLLILSVFFS
"
gene 393484..393894
/locus_tag="YLR125W"
/db_xref="GeneID:850816"
mRNA 393484..393894
/locus_tag="YLR125W"
/product="hypothetical protein"
/transcript_id="NM_001182012.1"
/db_xref="GI:296146656"
/db_xref="GeneID:850816"
CDS 393484..393894
/locus_tag="YLR125W"
/note="hypothetical protein; mutant has decreased Ty3
transposition; YLR125W is not an essential gene"
/codon_start=1
/product="hypothetical protein"
/protein_id="NP_013226.1"
/db_xref="GI:6323154"
/db_xref="SGD:S000004115"
/db_xref="GeneID:850816"
/translation="MGEILELTNKNFMSHLKKDITSQESLKSRIEDKNGDVASPKEDN
YPLLNETAAWPDGVITSEEGCSSSGEKENSGLCSEESSEEDPEEAEEESARAFGELVA
VLRDKDIPLNVLDEPQMKDWLEKYTGVYRSSWHG"
gene complement(394765..395520)
/locus_tag="YLR126C"
/db_xref="GeneID:850817"
mRNA complement(394765..395520)
/locus_tag="YLR126C"
/product="putative amidotransferase"
/transcript_id="NM_001182013.1"
/db_xref="GI:296146657"
/db_xref="GeneID:850817"
CDS complement(394765..395520)
/locus_tag="YLR126C"
/EC_number="2.4.2.-"
/note="Putative glutamine amidotransferase; has
Aft1p-binding motif in the promoter; may be involved in
copper and iron homeostasis; YLR126C is not an essential
protein; relocalizes from nucleus to cytoplasmic foci upon
DNA replication stress"
/codon_start=1
/product="putative amidotransferase"
/protein_id="NP_013227.1"
/db_xref="GI:6323155"
/db_xref="SGD:S000004116"
/db_xref="GeneID:850817"
/translation="MTVKKIAILYTDEDNEWSKPWGNFVDMAIKLLEQTRKLECIAED
VEYEVFHVQKNVFPQLSDLQKDEYLGIYITGSKYDSFDNEIEWIMKLRSFLNEMLTSK
TEYPPVAGICFGHQVIAAALGSSVGRNPKGFEGGVVSLKLNSVGQKLFGAQELNLSEV
HSDCVFDVPEGYQNWASSEKCQNQGFYRQNRVLTFQGHPEFNSDVAQKGLLKSQDKLT
LEEFNRYERQCQELDNNGIQAARNIWRLFLQKI"
gene complement(395758..398319)
/gene="APC2"
/locus_tag="YLR127C"
/gene_synonym="RSI1; TID2"
/db_xref="GeneID:850818"
mRNA complement(395758..398319)
/gene="APC2"
/locus_tag="YLR127C"
/gene_synonym="RSI1; TID2"
/product="anaphase promoting complex subunit 2"
/transcript_id="NM_001182014.1"
/db_xref="GI:296146658"
/db_xref="GeneID:850818"
CDS complement(395758..398319)
/gene="APC2"
/locus_tag="YLR127C"
/gene_synonym="RSI1; TID2"
/note="Subunit of the Anaphase-Promoting Complex/Cyclosome
(APC/C), which is a ubiquitin-protein ligase required for
degradation of anaphase inhibitors, including mitotic
cyclins, during the metaphase/anaphase transition;
component of the catalytic core of the APC/C; has
similarity to cullin Cdc53p"
/codon_start=1
/product="anaphase promoting complex subunit 2"
/protein_id="NP_013228.1"
/db_xref="GI:6323156"
/db_xref="SGD:S000004117"
/db_xref="GeneID:850818"
/translation="MSFQITPTRDLKVITDELQTLSSYIFHTNIVDDLNSLLTWMSPN
DAKSNHQLRPPSLRIKNIIKVLFPNNATTSPYSMINTSQANNSIVNEGNTNKELQLQL
FSTLKEFYIFQVRYHFFLHFNNINYLKDIQRWENYYEFPLRYVPIFDVNVNDWALELN
SLRHYLLNRNIKFKNNLRTRLDKLIMDDDFDLADNLIQWLKSANGSLSSTELIVNALY
SKINKFCEDNMSRVWNKRFMIMETFNKFINQYWSQFSKLVGCPEDDHELTTTVFNCFE
SNFLRIRTNEIFDICVLAYPDSKVTLLELRKIMKDFKDYTNIVTTFLSDFKKYILNPS
VTTVDALLRYVKTIKAFLVLDPTGRCLHSITTFVKPYFQERKHLVNVLLYAMLDLPEE
ELKEKINFNVDMKALLSLVDTLHDSDINQDTNITKRDKNKKSPFLWNLKVKGKRELNK
DLPIRHAMLYEHILNYYIAWVPEPNDMIPGNIKSSYIKTNLFEVLLDLFESREFFISE
FRNLLTDRLFTLKFYTLDEKWTRCLKLIREKIVKFTETSHSNYITNGILGLLETTAPA
ADADQSNLNSIDVMLWDIKCSEELCRKMHEVAGLDPIIFPKFISLLYWKYNCDTQGSN
DLAFHLPIDLERELQKYSDIYSQLKPGRKLQLCKDKGKVEIQLAFKDGRKLVLDVSLE
QCSVINQFDSPNDEPICLSLEQLSESLNIAPPRLTHLLDFWIQKGVLLKENGTYSVIE
HSEMDFDQAQKTAPMEIENSNYELHNDSEIERKYELTLQRSLPFIEGMLTNLGAMKLH
KIHSFLKITVPKDWGYNRITLQQLEGYLNTLADEGRLKYIANGSYEIVKNGHKNS"
gene 398530..399433
/gene="DCN1"
/locus_tag="YLR128W"
/db_xref="GeneID:850819"
mRNA join(398530..398532,398627..399433)
/gene="DCN1"
/locus_tag="YLR128W"
/product="Dcn1p"
/transcript_id="NM_001182015.1"
/db_xref="GI:296146659"
/db_xref="GeneID:850819"
CDS join(398530..398532,398627..399433)
/gene="DCN1"
/locus_tag="YLR128W"
/note="Scaffold-type E3 ligase required for cullin
neddylation and ubiquitin ligase activation; contains a
ubiquitin-binding domain (UBA) for ubiquitin and Nedd8
(Rub1p) interaction and a PONY domain involved in cullin
binding and neddylation"
/codon_start=1
/product="NEDD8 ligase DCN1"
/protein_id="NP_013229.1"
/db_xref="GI:6323157"
/db_xref="SGD:S000004118"
/db_xref="GeneID:850819"
/translation="MSNNKIKRKDASPEQEAIESFTSLTKCDPKVSRKYLQRNHWNIN
YALNDYYDKEIGTFTDEVSTVAHPPVYPKELTQVFEHYINNNLFDIDSLVKFIEELGY
NLEDLATLCLAHLLGYKKLEEPLKREDFLSTWFMQGCSTISDMQECIKTLDVKLHEDL
QYFTQIYNYAFNLILDPNRKDIDTDEGIQYWKLFFQPEYPVRMEPDLLEAWFRFLRDE
GKTTISKDTWRMLLLFFKRYPTIQKIISDYDETAAWPFIIDEFYECLQDQQ"
gene 399657..402488
/gene="DIP2"
/locus_tag="YLR129W"
/gene_synonym="UTP12"
/db_xref="GeneID:850820"
mRNA 399657..402488
/gene="DIP2"
/locus_tag="YLR129W"
/gene_synonym="UTP12"
/product="Dip2p"
/transcript_id="NM_001182016.1"
/db_xref="GI:296146660"
/db_xref="GeneID:850820"
CDS 399657..402488
/gene="DIP2"
/locus_tag="YLR129W"
/gene_synonym="UTP12"
/note="Nucleolar protein, specifically associated with the
U3 snoRNA, part of the large ribonucleoprotein complex
known as the small subunit (SSU) processome, required for
18S rRNA biogenesis, part of the active pre-rRNA
processing complex"
/codon_start=1
/product="Dip2p"
/protein_id="NP_013230.1"
/db_xref="GI:6323158"
/db_xref="SGD:S000004119"
/db_xref="GeneID:850820"
/translation="MVKSYQRFEQAAAFGVIASNANCVWIPASSGNSNGSGPGQLITS
ALEDVNIWDIKTGDLVSKLSDGLPPGASDARGAKPAECTYLEAHKDTDLLAVGYADGV
IKVWDLMSKTVLLNFNGHKAAITLLQFDGTGTRLISGSKDSNIIVWDLVGEVGLYKLR
SHKDSITGFWCQGEDWLISTSKDGMIKLWDLKTHQCIETHIAHTGECWGLAVKDDLLI
TTGTDSQVKIWKLDIENDKMGGKLTEMGIFEKQSKQRGLKIEFITNSSDKTSFFYIQN
ADKTIETFRIRKEEEIARGLKKREKRLKEKGLTEEEIAKSIKESYSSFILHPFQTIRS
LYKIKSASWTTVSSSKLELVLTTSSNTIEYYSIPYEKRDPTSPAPLKTHTIELQGQRT
DVRSIDISDDNKLLATASNGSLKIWNIKTHKCIRTFECGYALTCKFLPGGLLVILGTR
NGELQLFDLASSSLLDTIEDAHDAAIWSLDLTSDGKRLVTGSADKTVKFWDFKVENSL
VPGTKNKFLPVLKLHHDTTLELTDDILCVRVSPDDRYLAISLLDNTVKVFFLDSMKFY
LSLYGHKLPVLSIDISFDSKMIITSSADKNIKIWGLDFGDCHKSLFAHQDSIMNVKFL
PQSHNFFSCSKDAVVKYWDGEKFECIQKLYAHQSEVWALAVATDGGFVVSSSHDHSIR
IWEETEDQVFLEEEKEKELEEQYEDTLLTSLEEGNGDDAFKADASGEGVEDEASGVHK
QTLESLKAGERLMEALDLGIAEIEGLEAYNRDMKLWQRKKLGEAPIKPQGNAVLIAVN
KTPEQYIMDTLLRIRMSQLEDALMVMPFSYVLKFLKFIDTVMQNKTLLHSHLPLICKN
LFFIIKFNHKELVSQKNEELKLQINRVKTELRSALKSTEDDLGFNVQGLKFVKQQWNL
RHNYEFVDEYDQQEKESNSARKRVFGTVI"
gene complement(402794..404062)
/gene="ZRT2"
/locus_tag="YLR130C"
/db_xref="GeneID:850821"
mRNA complement(402794..404062)
/gene="ZRT2"
/locus_tag="YLR130C"
/product="low-affinity Zn(2+) transporter ZRT2"
/transcript_id="NM_001182017.1"
/db_xref="GI:296146661"
/db_xref="GeneID:850821"
CDS complement(402794..404062)
/gene="ZRT2"
/locus_tag="YLR130C"
/note="Low-affinity zinc transporter of the plasma
membrane; transcription is induced under low-zinc
conditions by the Zap1p transcription factor"
/codon_start=1
/product="low-affinity Zn(2+) transporter ZRT2"
/protein_id="NP_013231.1"
/db_xref="GI:6323159"
/db_xref="SGD:S000004120"
/db_xref="GeneID:850821"
/translation="MVDLIARDDSVDTCQASNGYNGHAGLRILAVFIILISSGLGVYF
PILSSRYSFIRLPNWCFFIAKFFGSGVIVATAFVHLLQPAAEALGDECLGGTFAEYPW
AFGICLMSLFLLFFTEIITHYFVAKTLGHDHGDHGEVTSIDVDAPSSGFVIRNMDSDP
VSFNNEAAYSIHNDKTPYTTRNEEIVATPIKEKEPGSNVTNYDLEPGKTESLANELVP
TSSHATNLASVPGKDHYSHENDHQDVSQLATRIEEEDKEQYLNQILAVFILEFGIIFH
SVFVGLSLSVAGEEFETLFIVLTFHQMFEGLGLGTRVAETNWPESKKYMPWLMGLAFT
LTSPIAVAVGIGVRHSWIPGSRRALIANGVFDSISSGILIYTGLVELMAHEFLYSNQF
KGPDGLKKMLSAYLIMCCGAALMALLGKWA"
gene complement(404510..406822)
/gene="ACE2"
/locus_tag="YLR131C"
/db_xref="GeneID:850822"
mRNA complement(404510..406822)
/gene="ACE2"
/locus_tag="YLR131C"
/product="Ace2p"
/transcript_id="NM_001182018.1"
/db_xref="GI:296146662"
/db_xref="GeneID:850822"
CDS complement(404510..406822)
/gene="ACE2"
/locus_tag="YLR131C"
/note="Transcription factor required for septum
destruction after cytokinesis; phosphorylation by Cbk1p
blocks nuclear exit during M/G1 transition, causing
localization to daughter cell nuclei, and also increases
Ace2p activity; phosphorylation by Cdc28p and Pho85p
prevents nuclear import during cell cycle phases other
than cytokinesis; part of RAM network that regulates
cellular polarity and morphogenesis; ACE2 has a paralog,
SWI5, that arose from the whole genome duplication"
/codon_start=1
/product="Ace2p"
/protein_id="NP_013232.1"
/db_xref="GI:6323160"
/db_xref="SGD:S000004121"
/db_xref="GeneID:850822"
/translation="MDNVVDPWYINPSGFAKDTQDEEYVQHHDNVNPTIPPPDNYILN
NENDDGLDNLLGMDYYNIDDLLTQELRDLDIPLVPSPKTGDGSSDKKNIDRTWNLGDE
NNKVSHYSKKSMSSHKRGLSGTAIFGFLGHNKTLSISSLQQSILNMSKDPQPMELINE
LGNHNTVKNNNDDFDHIRENDGENSYLSQVLLKQQEELRIALEKQKEVNEKLEKQLRD
NQIQQEKLRKVLEEQEEVAQKLVSGATNSNSKPGSPVILKTPAMQNGRMKDNAIIVTT
NSANGGYQFPPPTLISPRMSNTSINGSPSRKYHRQRYPNKSPESNGLNLFSSNSGYLR
DSELLSFSPQNYNLNLDGLTYNDHNNTSDKNNNDKKNSTGDNIFRLFEKTSPGGLSIS
PRINGNSLRSPFLVGTDKSRDDRYAAGTFTPRTQLSPIHKKRESVVSTVSTISQLQDD
TEPIHMRNTQNPTLRNANALASSSVLPPIPGSSNNTPIKNSLPQKHVFQHTPVKAPPK
NGSNLAPLLNAPDLTDHQLEIKTPIRNNSHCEVESYPQVPPVTHDIHKSPTLHSTSPL
PDEIIPRTTPMKITKKPTTLPPGTIDQYVKELPDKLFECLYPNCNKVFKRRYNIRSHI
QTHLQDRPYSCDFPGCTKAFVRNHDLIRHKISHNAKKYICPCGKRFNREDALMVHRSR
MICTGGKKLEHSINKKLTSPKKSLLDSPHDTSPVKETIARDKDGSVLMKMEEQLRDDM
RKHGLLDPPPSTAAHEQNSNRTLSNETDAL"
gene complement(407283..408155)
/gene="USB1"
/locus_tag="YLR132C"
/db_xref="GeneID:850823"
mRNA complement(407283..408155)
/gene="USB1"
/locus_tag="YLR132C"
/product="Usb1p"
/transcript_id="NM_001182019.1"
/db_xref="GI:296146663"
/db_xref="GeneID:850823"
CDS complement(407283..408155)
/gene="USB1"
/locus_tag="YLR132C"
/note="Putative phosphodiesterase specific for U6 snRNA 3'
end modification; trims the 3' poly(u) tract to leave a
terminal 3' phosphate; human homolog, hUSB1 (aka C16orf57)
produces a 2',3' cyclic phosphate; mutations in hUSB1 are
associated with a rare skin condition (OMIM 604173);
essential protein that localizes to the nucleus and
mitochondria; overexpression suppresses the respiratory
defects of oxa1 and mtf2 mutants"
/codon_start=1
/product="Usb1p"
/protein_id="NP_013233.1"
/db_xref="GI:6323161"
/db_xref="SGD:S000004122"
/db_xref="GeneID:850823"
/translation="MEFISADYSSSDGSDTESESSNKSEVQIEYTEKTCIQKADSTDL
PAIPDSIILKYHIPPNLQKYEHQDMNMSRFWRSFTYFEWRPTPAIHRQLQKIICKYKE
TFMKQEYTNPYQLVDFDPLFISHLGAPKPLHVSLTRSLLFETEEQRHVFIQEMRNGLR
NNEITPFKLQICSYPKLYISERANTLYLGLPVSECPNKAQISPFKTIIAEALQKSGIS
NYQDLIVSRQNLHVSIAIASNPSKATLKRYQQLNETMGALLLLNNDFAYKLEFLVNSI
YCDENRHSIRIPFN"
gene 408445..410193
/gene="CKI1"
/locus_tag="YLR133W"
/db_xref="GeneID:850824"
mRNA 408445..410193
/gene="CKI1"
/locus_tag="YLR133W"
/product="bifunctional choline kinase/ethanolamine kinase
CKI1"
/transcript_id="NM_001182020.1"
/db_xref="GI:296146664"
/db_xref="GeneID:850824"
CDS 408445..410193
/gene="CKI1"
/locus_tag="YLR133W"
/EC_number="2.7.1.32"
/note="Choline kinase; catalyzes the first step in
phosphatidylcholine synthesis via the CDP-choline (Kennedy
pathway); exhibits some ethanolamine kinase activity
contributing to phosphatidylethanolamine synthesis via the
CDP-ethanolamine pathway; CKI1 has a paralog, EKI1, that
arose from the whole genome duplication"
/codon_start=1
/product="bifunctional choline kinase/ethanolamine kinase
CKI1"
/protein_id="NP_013234.1"
/db_xref="GI:6323162"
/db_xref="SGD:S000004123"
/db_xref="GeneID:850824"
/translation="MVQESRPGSVRSYSVGYQARSRSSSQRRHSLTRQRSSQRLIRTI
SIESDVSNITDDDDLRAVNEGVAGVQLDVSETANKGPRRASATDVTDSLGSTSSEYIE
IPFVKETLDASLPSDYLKQDILNLIQSLKISKWYNNKKIQPVAQDMNLVKISGAMTNA
IFKVEYPKLPSLLLRIYGPNIDNIIDREYELQILARLSLKNIGPSLYGCFVNGRFEQF
LENSKTLTKDDIRNWKNSQRIARRMKELHVGVPLLSSERKNGSACWQKINQWLRTIEK
VDQWVGDPKNIENSLLCENWSKFMDIVDRYHKWLISQEQGIEQVNKNLIFCHNDAQYG
NLLFTAPVMNTPSLYTAPSSTSLTSQSSSLFPSSSNVIVDDIINPPKQEQSQDSKLVV
IDFEYAGANPAAYDLANHLSEWMYDYNNAKAPHQCHADRYPDKEQVLNFLYSYVSHLR
GGAKEPIDEEVQRLYKSIIQWRPTVQLFWSLWAILQSGKLEKKEASTAITREEIGPNG
KKYIIKTEPESPEEDFVENDDEPEAGVSIDTFDYMAYGRDKIAVFWGDLIGLGIITEE
ECKNFSSFKFLDTSYL"
gene 410723..412414
/gene="PDC5"
/locus_tag="YLR134W"
/db_xref="GeneID:850825"
mRNA 410723..412414
/gene="PDC5"
/locus_tag="YLR134W"
/product="indolepyruvate decarboxylase 5"
/transcript_id="NM_001182021.1"
/db_xref="GI:296146665"
/db_xref="GeneID:850825"
CDS 410723..412414
/gene="PDC5"
/locus_tag="YLR134W"
/EC_number="4.1.1.74"
/EC_number="4.1.1.72"
/EC_number="4.1.1.-"
/EC_number="4.1.1.1"
/note="Minor isoform of pyruvate decarboxylase, key enzyme
in alcoholic fermentation, decarboxylates pyruvate to
acetaldehyde, regulation is glucose- and
ethanol-dependent, repressed by thiamine, involved in
amino acid catabolism"
/codon_start=1
/product="indolepyruvate decarboxylase 5"
/protein_id="NP_013235.1"
/db_xref="GI:6323163"
/db_xref="SGD:S000004124"
/db_xref="GeneID:850825"
/translation="MSEITLGKYLFERLSQVNCNTVFGLPGDFNLSLLDKLYEVKGMR
WAGNANELNAAYAADGYARIKGMSCIITTFGVGELSALNGIAGSYAEHVGVLHVVGVP
SISSQAKQLLLHHTLGNGDFTVFHRMSANISETTAMITDIANAPAEIDRCIRTTYTTQ
RPVYLGLPANLVDLNVPAKLLETPIDLSLKPNDAEAEAEVVRTVVELIKDAKNPVILA
DACASRHDVKAETKKLMDLTQFPVYVTPMGKGAIDEQHPRYGGVYVGTLSRPEVKKAV
ESADLILSIGALLSDFNTGSFSYSYKTKNIVEFHSDHIKIRNATFPGVQMKFALQKLL
DAIPEVVKDYKPVAVPARVPITKSTPANTPMKQEWMWNHLGNFLREGDIVIAETGTSA
FGINQTTFPTDVYAIVQVLWGSIGFTVGALLGATMAAEELDPKKRVILFIGDGSLQLT
VQEISTMIRWGLKPYIFVLNNNGYTIEKLIHGPHAEYNEIQGWDHLALLPTFGARNYE
THRVATTGEWEKLTQDKDFQDNSKIRMIEVMLPVFDAPQNLVKQAQLTAATNAKQ"
rep_origin 412668..412896
/note="ARS1215;
Autonomously Replicating Sequence"
/db_xref="SGD:S000118474"
gene 413281..415527
/gene="SLX4"
/locus_tag="YLR135W"
/db_xref="GeneID:850826"
mRNA 413281..415527
/gene="SLX4"
/locus_tag="YLR135W"
/product="Slx4p"
/transcript_id="NM_001182022.1"
/db_xref="GI:296146666"
/db_xref="GeneID:850826"
CDS 413281..415527
/gene="SLX4"
/locus_tag="YLR135W"
/note="Endonuclease involved in processing DNA; acts
during recombination and repair; cleaves branched
structures in a complex with Slx1p; involved interstrand
cross-link repair and in Rad1p/Rad10p-dependent removal of
3'-nonhomologous tails during DSBR via single-strand
annealing; relative distribution to nuclear foci increases
upon DNA replication stress"
/codon_start=1
/product="Slx4p"
/protein_id="NP_013236.1"
/db_xref="GI:6323164"
/db_xref="SGD:S000004125"
/db_xref="GeneID:850826"
/translation="MELQRAQRNLKFLQNEDYVNVTDQTNLNGESQNAYSLGMETQVP
EMQFSLSSDDDSIGTQVKSVTAQKSPMTQETTKNDTERNKDVDKSCNPVSTSHPDLGG
SNIEENIFINTQIQSRLDDAEEETNLKLKLEKFKYSFKSSNADDTHSNANVTAKRRPA
IRKANSKLKTKPKTKRDPKIIKNITDFNINNYERSRTASLLKQLSGKHKKVLDIIKTQ
NEGNSDKPPRARNNKGEKATFDTYSEQEWKDIMKLLLQKFPQSEETDLNEVQKFLYGS
EKSSNSLDNQESSQQRLWTASQLPPELPDEAIQPEQEERIRDTQSAVNFLSLSQVMDD
KSEIMKDEESIIISRGDSTSSQEYGNGLEPQQPVGNVVGEDIELAVGTRINAFSLTDY
KACKPMSVEVSRRCENSTDNDYDNISIVSDTTDETSTLFPLDQYRYVFIENDERPPLA
TDTIGSTQFFTPNTSPLDGIIDLTQESFKAVRSLISPLKVENNKTGVTSQASNQVQVP
ATRTPTIIPQKNLTTTLKTEEEKNNIGSSIRVKLLQESVVKLNPKLVKHNFYRVEAND
SEEEETEFDDQFCIADIQLVDSSKISTKDSTQNPTTSNDIIDTSAASSIASPEKFCEI
MMSQSMKELRQSLKTVGLKPMRTKVEIIQSLQTASQILSTANPDNKGEHGGVANFSKI
EIFDHLTELIEAFPDFLERIYTFEPIPLNELIEKLFSAEPFVSQIDEMTIREWADVQG
ICLRNDKK"
gene complement(415801..416658)
/gene="TIS11"
/locus_tag="YLR136C"
/gene_synonym="CTH2"
/db_xref="GeneID:850827"
mRNA complement(415801..416658)
/gene="TIS11"
/locus_tag="YLR136C"
/gene_synonym="CTH2"
/product="Tis11p"
/transcript_id="NM_001182023.1"
/db_xref="GI:296146667"
/db_xref="GeneID:850827"
CDS complement(415801..416658)
/gene="TIS11"
/locus_tag="YLR136C"
/gene_synonym="CTH2"
/note="mRNA-binding protein expressed during iron
starvation; binds to a sequence element in the
3'-untranslated regions of specific mRNAs to mediate their
degradation; involved in iron homeostasis; protein
increases in abundance and relative distribution to the
nucleus increases upon DNA replication stress"
/codon_start=1
/product="Tis11p"
/protein_id="NP_013237.1"
/db_xref="GI:6323165"
/db_xref="SGD:S000004126"
/db_xref="GeneID:850827"
/translation="MWAQLSYTRPESQKTDLTSLFSTDQEQNPLNDYQYQINIRELEE
YYNKTILNEDNIQETSSEISSAVSFSPPKNTNAIQPGLLYDPQLMNPFLPSAHLNSTA
PTTFKKKLEVQINPDYVPKSSQLPLTSQNLQQLSQQKPKNDASFSSEKESSAQPKVKS
QVQETPKQLYKTELCESFTLKGSCPYGSKCQFAHGLGELKVKKSCKNFRTKPCVNWEK
LGYCPYGRRCCFKHGDDNDIAVYVKAGTYCNVSSTSKQSDEKRSNGRGSAKKKNLNVK
VKALQRMTW"
gene 417006..418109
/gene="RKM5"
/locus_tag="YLR137W"
/db_xref="GeneID:850828"
mRNA 417006..418109
/gene="RKM5"
/locus_tag="YLR137W"
/product="Rkm5p"
/transcript_id="NM_001182024.1"
/db_xref="GI:296146668"
/db_xref="GeneID:850828"
CDS 417006..418109
/gene="RKM5"
/locus_tag="YLR137W"
/note="Protein lysine methyltransferase; monomethylates
Lys-46 of the ribosomal large subunit Rpl1a/Rpl1b; member
of the seven beta-strand methyltransferase superfamily;
orthologs only found among fungal species"
/codon_start=1
/product="Rkm5p"
/protein_id="NP_013238.1"
/db_xref="GI:6323166"
/db_xref="SGD:S000004127"
/db_xref="GeneID:850828"
/translation="MAFKLWLLDEETIYEHVFERYTQLEGQSGKLAQDLGIQDRRGGV
LEITFEPSGLEGGRKKKRVRRRNKASSVEEDQNVAVDSYHVSVGQSISSLRSSRDNGN
STTGYVLWSTTPFFINWLLYSTSAAPFRLGSQVEVTCGSSCEGHKLELPRLVDLTGAD
RGKRGILELGAGISGILPVILGNFVDTYVSTDQKGILNKLKDNIMENLSQLTRKRCIS
RSLRLELPTVEPVGDADITAASLPSKSTLHLEVAALDWEKINLQDKKTHSLHPELSLI
GETCSSVYVIAMDVIYNEYLIDPFLKTLKQLKHWLQTTYNLQFHVLVGIHLRSQEVTT
LFLEKAIIEYDFTVYDIVDQVIQESRFNFYLIT"
gene 418437..421394
/gene="NHA1"
/locus_tag="YLR138W"
/db_xref="GeneID:850829"
mRNA 418437..421394
/gene="NHA1"
/locus_tag="YLR138W"
/product="Nha1p"
/transcript_id="NM_001182025.1"
/db_xref="GI:296146669"
/db_xref="GeneID:850829"
CDS 418437..421394
/gene="NHA1"
/locus_tag="YLR138W"
/note="Na+/H+ antiporter involved in sodium and potassium
efflux through the plasma membrane; required for alkali
cation tolerance at acidic pH"
/codon_start=1
/product="Nha1p"
/protein_id="NP_013239.1"
/db_xref="GI:6323167"
/db_xref="SGD:S000004128"
/db_xref="GeneID:850829"
/translation="MAIWEQLEVSKAHVAYACVGVFSSIFSLVSLYVKEKLYIGESTV
AGIFGLIVGPVCLNWFNPLKWGNSDSITLEITRIVLCLQIFAVAVELPRKYMLKHWVS
VTMLLLPVMTAGWLIIGLFVWILIPGLNFSASLLISACITATDPILAQSVVSGKFAQR
VPGHLRNLLSAESGCNDGMAFPFLFLSMNLILHPGNGREIVKDWICVTILYECLFGCL
LGCFIGYVGRITIRFAEKKNIIDRESFLAFYVVLAFMCAGFGSILGVDDLLVSFAAGA
TFAWDGWFSQKTQESNVSTVIDLLLNYAYFIYFGAIIPWSQFNNGEIGTNVWRLIILS
IVVIFLRRIPAVMILRPLIPDIKSWREALFVGHFGPIGVGAIFAAILARGELESTFSD
EPTPLNVVPSKEESKHWQLIACIWPITCFFIVTSIIVHGSSVAIITLGRHLNTITLTK
TFTTHTTNGDNGKSSWMQRLPSLDKAGRSFSLHRMDTQMTLSGDEGEAEEGGGRKGLA
GGEDEEGLNNDQIGSVATSGIPARPAGGMPRRRKLSRKEKRLNRRQKLRNKGREIFSS
RSKNEMYDDDELNDLGRERLQKEKEARAATFALSTAVNTQRNEEIGMGGDEEEDEYTP
EKEYSDNYNNTPSFESSERSSSLRGRTYVPRNRYDGEETESEIESEDEMENESERSMA
SSEERRIRKMKEEEMKPGTAYLDGNRMIIENKQGEILNQVDIEDRNEARDDEVSVDST
AHSSLTTTMTNLSSSSGGRLKRILTPTSLGKIHSLVDKGKDKNKNSKYHAFKIDNLLI
IENEDGDVIKRYKINPHKSDDDKSKNRPRNDSVVSRALTAVGLKSKANSGVPPPVDEE
KAIEGPSRKGPGMLKKRTLTPAPPRGVQDSLDLEDEPSSEEDLGDSYNMDDSEDYDDN
AYESETEFERQRRLNALGEMTAPADQDDEELPPLPVEAQTGNDGPGTAEGKKKQKSAA
VKSALSKTLGLNK"
gene complement(421542..423473)
/gene="SLS1"
/locus_tag="YLR139C"
/db_xref="GeneID:850830"
mRNA complement(421542..423473)
/gene="SLS1"
/locus_tag="YLR139C"
/product="Sls1p"
/transcript_id="NM_001182026.1"
/db_xref="GI:296146670"
/db_xref="GeneID:850830"
CDS complement(421542..423473)
/gene="SLS1"
/locus_tag="YLR139C"
/note="Mitochondrial membrane protein that coordinates
expression of mitochondrially-encoded genes; may
facilitate delivery of mRNA to membrane-bound translation
machinery"
/codon_start=1
/product="Sls1p"
/protein_id="NP_013240.1"
/db_xref="GI:6323168"
/db_xref="SGD:S000004129"
/db_xref="GeneID:850830"
/translation="MWKFNKKLARLTYRLYSSSGPSSPLHGKKKLPQNLKFVVLNPTQ
SGLVKNDQKQPRHRPSKKRSHKETGDNNLDFGSKLLVFEKQNSLDSALNSIRLKKPTS
ASLPSLEYNALLQSLTSSYNRYQLREFISTHQPDSSSHLTHWKKSKLSQYIIEKIWNC
QPISTPTTPTGIKSTSLTFQFDSPREIFLLLITQNGKILTNFNKLGLTFIISIQDNEL
TVKGSPSLLKYAEISLNKIWSNITHENVRMYSLMPSKDVINLIQKETHTFFEYLPDLQ
MYKISALSTKKISMAKVFLLNAVASNPNTTQHHHTIASPALKTELYPFNNTLENLDWL
NKSQDWARLQSVVPKNCTDLMTPTENATPELTDAQVSQFESSLSKNIPSLSPSDSISQ
SLSITLGHSLQSASFSSIFQPLIHKSFISKLLNLPMYKESSSSAVPVPVPLDQHLITN
AHQSFIQLNFTPVPPTSGSSSSPFLQIWFEIDEFDNIVTTSMRPLLKLQENSVILRTP
QCQTDYKITSDYIQDLLPDFDQTNPDAWLSEQKGLQEFLLKSHWKLNKYQNLMKKINI
SLPDNLIQQYQLTDVLTHRVLNLRFPTNTAQDDKYIIQYSDISRGFLNNGSYRQLDFI
NVNPSETSLKTFINDVLSF"
gene 423683..424774
/gene="RRN5"
/locus_tag="YLR141W"
/db_xref="GeneID:850832"
mRNA 423683..424774
/gene="RRN5"
/locus_tag="YLR141W"
/product="Rrn5p"
/transcript_id="NM_001182028.1"
/db_xref="GI:296146671"
/db_xref="GeneID:850832"
CDS 423683..424774
/gene="RRN5"
/locus_tag="YLR141W"
/note="Protein involved in transcription of rDNA by RNA
polymerase I; transcription factor, member of UAF
(upstream activation factor) family along with Rrn9p and
Rrn10p"
/codon_start=1
/product="Rrn5p"
/protein_id="NP_013242.1"
/db_xref="GI:6323170"
/db_xref="SGD:S000004131"
/db_xref="GeneID:850832"
/translation="MEHQQLRKYVELYNKEVEEFYNGAASGRPAEFHPSKVHVKSIHE
KAGTANAGVEISSVGVDWDSEEKNTFFWCLSRYSIHRVDEWRSLLPRKSAMEILGYYR
LLRRASASARSRKAGDDGAPIAYEMSAEWVALETKLSETVMAITEGAAEVADEEGHCE
GLIDYESWKRRWVAIYSHSRIAEIRPLPRHALPLSRSATQTLERCVSRYTRTLLWCTA
LAGMASRSVSARAAESRGHKSLPTVVTRRQVERALCTEARSRDLHVLPRRIVLTLRKW
ELDYPREGKLFRTKEMAHLFLQSQLSRRDAPPVHQDENQENQENQENQEQDNTASEGE
SEAERDEIDEADLFRSALHENQLLKWLSK"
gene 425186..426616
/gene="PUT1"
/locus_tag="YLR142W"
/db_xref="GeneID:850833"
mRNA 425186..426616
/gene="PUT1"
/locus_tag="YLR142W"
/product="proline dehydrogenase"
/transcript_id="NM_001182029.1"
/db_xref="GI:296146672"
/db_xref="GeneID:850833"
CDS 425186..426616
/gene="PUT1"
/locus_tag="YLR142W"
/EC_number="1.5.99.8"
/note="Proline oxidase, nuclear-encoded mitochondrial
protein involved in utilization of proline as sole
nitrogen source; PUT1 transcription is induced by Put3p in
the presence of proline and the absence of a preferred
nitrogen source"
/codon_start=1
/product="proline dehydrogenase"
/protein_id="NP_013243.1"
/db_xref="GI:6323171"
/db_xref="SGD:S000004132"
/db_xref="GeneID:850833"
/translation="MIASKSSLLVTKSRIPSLCFPLIKRSYVSKTPTHSNTAANLMVE
TPAANANGNSVMAPPNSINFLQTLPKKELFQLGFIGIATLNSFFLNTIIKLFPYIPIP
VIKFFVSSLYCGGENFKEVIECGKRLQKRGISNMMLSLTIENSEGTKSLSSTPVDQIV
KETISSVHNILLPNIIGQLESKPINDIAPGYIALKPSALVDNPHEVLYNFSNPAYKAQ
RDQLIENCSKITKEIFELNQSLLKKYPERKAPFMVSTIDAEKYDLQENGVYELQRILF
QKFNPTSSKLISCVGTWQLYLRDSGDHILHELKLAQENGYKLGLKLVRGAYIHSEKNR
NQIIFGDKTGTDENYDRIITQVVNDLIINGEDSYFGHLVVASHNYQSQMLVTNLLKST
QDNSYAKSNIVLGQLLGMADNVTYDLITNHGAKNIIKYVPWGPPLETKDYLLRRLQEN
GDAVRSDNGWPLIKAIAKSIPKRVGL"
gene 427132..427203
/locus_tag="tD(GUC)L1"
/db_xref="GeneID:850834"
tRNA 427132..427203
/locus_tag="tD(GUC)L1"
/product="tRNA-Asp"
/note="Aspartate tRNA (tRNA-Asp), predicted by tRNAscan-SE
analysis"
/db_xref="SGD:S000006541"
/db_xref="GeneID:850834"
gene 427329..429386
/gene="DPH6"
/locus_tag="YLR143W"
/db_xref="GeneID:850835"
mRNA 427329..429386
/gene="DPH6"
/locus_tag="YLR143W"
/product="Dph6p"
/transcript_id="NM_001182030.1"
/db_xref="GI:296146673"
/db_xref="GeneID:850835"
CDS 427329..429386
/gene="DPH6"
/locus_tag="YLR143W"
/note="Diphthamide synthetase; catalyzes the last
amidation step of diphthamide biosynthesis using ammonium
and ATP; evolutionarily conserved in eukaryotes; green
fluorescent protein (GFP)-tagged protein localizes to the
cytoplasm; DPH6/YLR143W is not an essential gene"
/codon_start=1
/product="Dph6p"
/protein_id="NP_013244.1"
/db_xref="GI:6323172"
/db_xref="SGD:S000004133"
/db_xref="GeneID:850835"
/translation="MKFIALISGGKDSFYNIFHCLKNNHELIALGNIYPKESEEQELD
SFMFQTVGHDLIDYYSKCIGVPLFRRSILRNTSNNVELNYTATQDDEIEELFELLRTV
KDKIPDLEAVSVGAILSSYQRTRVENVCSRLGLVVLSYLWQRDQAELMGEMCLMSKDV
NNVENDTNSGNKFDARIIKVAAIGLNEKHLGMSLPMMQPVLQKLNQLYQVHICGEGGE
FETMVLDAPFFQHGYLELIDIVKCSDGEVHNARLKVKFQPRNLSKSFLLNQLDQLPVP
SIFGNNWQDLTQNLPKQQAKTGEQRFENHMSNALPQTTINKTNDKLYISNLQSRKSET
VEKQSEDIFTELADILHSNQIPRNHILSASLLIRDMSNFGKINKIYNEFLDLSKYGPL
PPSRACVGSKCLPEDCHVQLSVVVDVKNTGKEKINKNKGGLHVQGRSYWAPCNIGPYS
QSTWLNDDANQVSFISGQIGLVPQSMEILGTPLTDQIVLALQHFDTLCETIGAQEKLL
MTCYISDESVLDSVIKTWAFYCSNMNHRSDLWMDKSDDVEKCLVLVKISELPRGAVAE
FGGVTCKRLIVDDNDSDKKEREENDDVSTVFQKLNLNIEGFHNTTVSAFGYNRNFITG
FVDSREELELILEKTPKSAQITLYYNPKEIITFHHHIGYYPVEKLFDYRGKEHRFGLH
IRS"
gene complement(429677..432016)
/gene="ACF2"
/locus_tag="YLR144C"
/gene_synonym="ENG2; PCA1"
/db_xref="GeneID:850836"
mRNA complement(429677..432016)
/gene="ACF2"
/locus_tag="YLR144C"
/gene_synonym="ENG2; PCA1"
/product="Acf2p"
/transcript_id="NM_001182031.1"
/db_xref="GI:296146674"
/db_xref="GeneID:850836"
CDS complement(429677..432016)
/gene="ACF2"
/locus_tag="YLR144C"
/gene_synonym="ENG2; PCA1"
/EC_number="3.2.1.6"
/note="Intracellular beta-1,3-endoglucanase; expression is
induced during sporulation; may have a role in cortical
actin cytoskeleton assembly; protein abundance increases
in response to DNA replication stress"
/codon_start=1
/product="Acf2p"
/protein_id="NP_013245.1"
/db_xref="GI:6323173"
/db_xref="SGD:S000004134"
/db_xref="GeneID:850836"
/translation="MCYSRQAIPPPVPNRPGGTTNRGPPPLPPRANVQPPVCSSENSS
KPRENRVAGESLRTPSSSNPLADSQVNSDNIFQSPVLSNLKAPPSVFNKVQHPVPKPN
IDDQSVDPLETNKFYTNMLLDDNTQPIWTHPYSIWFSRDPELFGLAANHTLASQRVFD
TTTNPPRFYFNPTNIKSFVFKAREFVSSNDIKLEFRDMKHMSMCLLMSLSSSQFIEFP
LVQGMGFVTAIYHDLGFELRSAVGFRSLERISVNERYGKYNIQLENNRNWILYLTSPD
YSFPQDFQISLLDSNTIISSHKINGLICQLSADSVPSIDMAAGCYPVYCDLSGQTVDE
HFTNYRFNYTVAGYSQSGTTLMYALPHHKAAFTPEMQEREIASSLDSTVKGLMTGYLT
NSFDMQVQVPQELGFEPVALSLNKKADYSQEKLSKIREAAVQEVQLSDPQQESNIDSM
YFSGKILAKYAWILYVTHYILHDENLTKELLSKLTIAMERFISNQQVLPLNYDVSWKG
IISSGSSSQDFGNSYYNDHHFHYSYHVITAAIISLVDSDLSGVTNNSWLENNRDWVEC
LIRDYSGVDNDDPYFPQFRSFDWFNGHSWAKGLFPSGDGKDEESTSEDVNSCYAIKLW
GLVTGNSKLTDIANLQLGIMRNVFQSYFLYESNNTVQPKEFIGNKVSGILFENKIDHA
TYFGMEPQYIHMIHAIPITSASSWVRTPNFVKEEWEEKMQPIIDQVNDGWKGIIMLNM
ALLDPKFSYDFFSQPDFNRNFLDNGQSLTWSLAYSGAFS"
gene 432168..432773
/gene="RMP1"
/locus_tag="YLR145W"
/db_xref="GeneID:850837"
mRNA 432168..432773
/gene="RMP1"
/locus_tag="YLR145W"
/product="Rmp1p"
/transcript_id="NM_001182032.1"
/db_xref="GI:296146675"
/db_xref="GeneID:850837"
CDS 432168..432773
/gene="RMP1"
/locus_tag="YLR145W"
/note="Subunit of RNase MRP, which processes pre-rRNA and
has a role in cell cycle-regulated degradation of daughter
cell-specific mRNAs; unlike most subunits, not shared
between RNase MRP and nuclear RNase P"
/codon_start=1
/product="Rmp1p"
/protein_id="NP_013246.1"
/db_xref="GI:6323174"
/db_xref="SGD:S000004135"
/db_xref="GeneID:850837"
/translation="MDEMDNVIRSLEQEYRLILLLNHRNKNQHRAASWYGSFNEMKRN
CGQIITLFSSRRLQAKRLKDVEWVKLHRLLQRALFRQLKRWYWQFNGVIALGQFVTLG
CTLVTLLANVRALYMRLWEINETEFIRCGCLIKNLPRTKAKSVVNDVEELGEIIDEDI
GNNVQENELVITSIPKPLTENCKKKKKRKKKNKSAIDGIFG"
gene complement(432823..433725)
/gene="SPE4"
/locus_tag="YLR146C"
/db_xref="GeneID:850838"
mRNA complement(432823..433725)
/gene="SPE4"
/locus_tag="YLR146C"
/product="spermine synthase"
/transcript_id="NM_001182033.1"
/db_xref="GI:296146676"
/db_xref="GeneID:850838"
CDS complement(432823..433725)
/gene="SPE4"
/locus_tag="YLR146C"
/EC_number="2.5.1.22"
/note="Spermine synthase, required for the biosynthesis of
spermine and also involved in biosynthesis of pantothenic
acid"
/codon_start=1
/product="spermine synthase"
/protein_id="NP_013247.1"
/db_xref="GI:6323175"
/db_xref="SGD:S000004136"
/db_xref="GeneID:850838"
/translation="MVNNSQHPYIKDGWFREINDKSFPGQAFTMTVDSILYEARSEFQ
DILIFRNKVYGTVLVLDGIVQCTEFDEFAYQEMITHIAMFAHSNPKRVLIIGGGDGGV
LREVAKHSCVEDITMVEIDSSVIELSRKFLPTLSNGAFDDERLDLKLCDGFKFLQDIG
ASDVHKKFDVIITDSSDPEGPAEAFFQERYFELLKDALNPNGVVIMQSSENFWLNLKY
LHDLKNTAKKVFPNTEYCYTMVPTYTSGQLGLIVCSNNANIPLNIPQRKISEQEQGKL
KYYNPQIHSSAFVLPTWADKVINE"
gene 433870..434058
/locus_tag="YLR146W-A"
/db_xref="GeneID:3799977"
mRNA 433870..434058
/locus_tag="YLR146W-A"
/product="hypothetical protein"
/transcript_id="NM_001184685.1"
/db_xref="GI:296146677"
/db_xref="GeneID:3799977"
CDS 433870..434058
/locus_tag="YLR146W-A"
/codon_start=1
/product="hypothetical protein"
/protein_id="NP_001032582.1"
/db_xref="GI:82795259"
/db_xref="SGD:S000113566"
/db_xref="GeneID:3799977"
/translation="MDTEEKKKTTASVEHARMLQNEIQQLFAQLRDTNSQIRCDLNEF
EQIKESSTTADSTTNSAN"
gene complement(434158..434463)
/gene="SMD3"
/locus_tag="YLR147C"
/gene_synonym="SLT16"
/db_xref="GeneID:850839"
mRNA complement(434158..434463)
/gene="SMD3"
/locus_tag="YLR147C"
/gene_synonym="SLT16"
/product="Smd3p"
/transcript_id="NM_001182034.1"
/db_xref="GI:296146678"
/db_xref="GeneID:850839"
CDS complement(434158..434463)
/gene="SMD3"
/locus_tag="YLR147C"
/gene_synonym="SLT16"
/note="Core Sm protein Sm D3; part of heteroheptameric
complex (with Smb1p, Smd1p, Smd2p, Sme1p, Smx3p, and
Smx2p) that is part of the spliceosomal U1, U2, U4, and U5
snRNPs; homolog of human Sm D3"
/codon_start=1
/product="Smd3p"
/protein_id="NP_013248.1"
/db_xref="GI:6323176"
/db_xref="SGD:S000004137"
/db_xref="GeneID:850839"
/translation="MTMNGIPVKLLNEAQGHIVSLELTTGATYRGKLVESEDSMNVQL
RDVIATEPQGAVTHMDQIFVRGSQIKFIVVPDLLKNAPLFKKNSSRPMPPIRGPKRR"
gene 434641..437397
/gene="PEP3"
/locus_tag="YLR148W"
/gene_synonym="VAM8; VPS18; VPT18"
/db_xref="GeneID:850840"
mRNA 434641..437397
/gene="PEP3"
/locus_tag="YLR148W"
/gene_synonym="VAM8; VPS18; VPT18"
/product="Pep3p"
/transcript_id="NM_001182035.1"
/db_xref="GI:296146679"
/db_xref="GeneID:850840"
CDS 434641..437397
/gene="PEP3"
/locus_tag="YLR148W"
/gene_synonym="VAM8; VPS18; VPT18"
/note="Component of CORVET tethering complex; vacuolar
peripheral membrane protein that promotes vesicular
docking/fusion reactions in conjunction with SNARE
proteins, required for vacuolar biogenesis"
/codon_start=1
/product="Pep3p"
/protein_id="NP_013249.1"
/db_xref="GI:6323177"
/db_xref="SGD:S000004138"
/db_xref="GeneID:850840"
/translation="MIKTRIEEVQLQFLTGNTELTHLKVSNDQLIVTTQRTIYRINLQ
DPAIVNHFDCPLSKELETIMNVHVSPMGSVILIRTNFGRYMLLKDGEFTQLNKIKNLD
LSSLHWINETTFLMGIKKTPKLYRVELTGKDITTKLWYENKKLSGGIDGIAYWEGSLL
LTIKDNILYWRDVTNMKFPLVLPDESEQFERLKHHAIKKFDSYNGLFAWVTSNGIVFG
DLKEKQMEKDPASNNFGKFLSSSKVLLNFELPDYQNDKDHLIKDIVLTAFHILLLRKN
TVTMVSQLNNDVVFHETIPRHQLTGSNTDSNEKFLGLVRDSVKETFWCFSNINVFEII
IENEPNSVWNLLVRDNKFDKALSLKGLTVREIESVKLSKAMYLFHTAKDFHSAAQTLG
SMKDLSHFGEIALNFLQIKDYNDLNVILIKQLDNVPWKSTQVVLSSWIIWNFMKQLND
IELKINTTKPASTDEDNLLNWNLNLKEKSNELTKFLESHLEKLDNETVYQIMSKQNRQ
NELLIFASLINDMKFLLSFWIDQGNWYESLKILLTINNHDLVYKYSLILLLNSPEATV
STWMKIKDLDPNKLIPTILKFFTNWQNNSKLITNISEYPENYSLTYLKWCVREVPKMC
NPIVYNSILYMMITDPRNDMILENDIIKFMKSNENKYDLNFQLRLSLKFKKTKTSIFL
LTRLNLFEDAIDLALKNNLIDDCKVIVNDEILIEDYKLRKRLWLKIAKHLLLSMKDID
IKQLIRTILNDSNEILTIKDLLPFFNEYTTIANLKEELIKFLENHNMKMNEISEDIIN
SKNLKVEINTEISKFNEIYRILEPGKSCDECGKFLQIKKFIVFPCGHCFHWNCIIRVI
LNSNDYNLRQKTENFLKAKSKHNLNDLENIIVEKCGLCSDININKIDQPISIDETELA
KWNE"
gene complement(437631..439823)
/locus_tag="YLR149C"
/db_xref="GeneID:850841"
mRNA complement(437631..439823)
/locus_tag="YLR149C"
/product="hypothetical protein"
/transcript_id="NM_001182036.1"
/db_xref="GI:296146680"
/db_xref="GeneID:850841"
CDS complement(437631..439823)
/locus_tag="YLR149C"
/note="hypothetical protein; overexpression causes a cell
cycle delay or arrest; null mutation results in a decrease
in plasma membrane electron transport; YLR149C is not an
essential gene; protein abundance increases in response to
DNA replication stress"
/codon_start=1
/product="hypothetical protein"
/protein_id="NP_013250.1"
/db_xref="GI:6323178"
/db_xref="SGD:S000004139"
/db_xref="GeneID:850841"
/translation="MTIDGTGQSKEALQDERLNTGSDKVYQNYMMPALELYDAKVSIN
HWQLRDCIKPGSMNQSKLYYIYDHSIRVLDTDSSVLRSPVRRHNSIQPSNSGKNSTEK
TSTKGSRTTGSYISKNLHVPSEKLVEFNFKPRCFTELNGLTVCGGLIGSDDKGFPSNW
NRLAQDANISLPPPSQPINISKNISFPINSHYSNPNIWKGIVEFYNQETDTMMTFTLG
QFINNCVTLYDRASMQFDLFACNNDGHLYQCDVSNRDVTLVKRYADLKFPLNNASLSH
DGQTMVVSGDSNKFAVYNQNELTNQFSLHYDNHPSWGSSVNRVRRIPRFALPDESEYI
ENIYEAPNSDHGFYNSFSENDLQFATVFQNGTCAIYDIRNMATPMAEISSTRPHSHNG
AFRVCRFSYGLDDLLFISEHQGRVHVVDTRNYVNHQVIVIPDKVNMEYINERKHNTNH
NFTTNNNNENESNDSKNELQGADYRSLSRRRFSLPSMPNVTTEPWITMAQRIPKKYLE
PQILPFPKVMDKISNESVLFSTKGSSSSDVAHPYKRRCSFRVRRVSTSAPTADYSNNN
VNASLGTPAADSIATSSSNSAPQNLIDPLILSHQQASNDVFEDDEYYEAYNDVHSTYR
VSSDYHGVSARAFESFLRPPSTPDLPSDDDNFAANSRNNRGTSNFLRRPVITTQESNE
FSEENNISGIDWVEDRNGSSLIIGTDYGIMRWNINSWARRSFSSYDLC"
gene 440467..441288
/gene="STM1"
/locus_tag="YLR150W"
/gene_synonym="MPT4"
/db_xref="GeneID:850843"
mRNA 440467..441288
/gene="STM1"
/locus_tag="YLR150W"
/gene_synonym="MPT4"
/product="Stm1p"
/transcript_id="NM_001182037.1"
/db_xref="GI:296146681"
/db_xref="GeneID:850843"
CDS 440467..441288
/gene="STM1"
/locus_tag="YLR150W"
/gene_synonym="MPT4"
/note="Protein required for optimal translation under
nutrient stress; perturbs association of Yef3p with
ribosomes; involved in TOR signaling; binds G4 quadruplex
and purine motif triplex nucleic acid; helps maintain
telomere structure; protein abundance increases in
response to DNA replication stress"
/codon_start=1
/product="Stm1p"
/protein_id="NP_013251.1"
/db_xref="GI:6323179"
/db_xref="SGD:S000004140"
/db_xref="GeneID:850843"
/translation="MSNPFDLLGNDVEDADVVVLPPKEIVKSNTSSKKADVPPPSADP
SKARKNRPRPSGNEGAIRDKTAGRRNNRSKDVTDSATTKKSNTRRATDRHSRTGKTDT
KKKVNQGWGDDKKELSAEKEAQADAAAEIAEDAAEAEDAGKPKTAQLSLQDYLNQQAN
NQFNKVPEAKKVELDAERIETAEKEAYVPATKVKNVKSKQLKTKEYLEFDATFVESNT
RKNFGDRNNNSRNNFNNRRGGRGARKGNNTANATNSANTVQKNRNIDVSNLPSLA"
gene complement(441715..442737)
/gene="PCD1"
/locus_tag="YLR151C"
/db_xref="GeneID:850844"
mRNA complement(441715..442737)
/gene="PCD1"
/locus_tag="YLR151C"
/product="Pcd1p"
/transcript_id="NM_001182038.1"
/db_xref="GI:296146682"
/db_xref="GeneID:850844"
CDS complement(441715..442737)
/gene="PCD1"
/locus_tag="YLR151C"
/EC_number="3.6.1.-"
/note="Peroxisomal nudix pyrophosphatase with specificity
for coenzyme A and CoA derivatives, may function to remove
potentially toxic oxidized CoA disulfide from peroxisomes
to maintain the capacity for beta-oxidation of fatty
acids"
/codon_start=1
/product="Pcd1p"
/protein_id="NP_013252.1"
/db_xref="GI:6323180"
/db_xref="SGD:S000004141"
/db_xref="GeneID:850844"
/translation="MILSQRRMLSSKQLIENLIRYKFHKTPYTRSSIWPFKRNSAVII
LLFIGMKGELRVLLTKRSRTLRSFSGDVSFPGGKADYFQETFESVARREAEEEIGLPH
DPEVLHKEFGMKLDNLVMDMPCYLSRTFLSVKPMVCFLYKDKLEKHEDKYKVPLDIRK
FFGKLNPGETSSLFSVPLNDLVIHLLPEADEDVKSYQAEYFERKEYKLNWGGIKWLIM
HYHFHVANNNEMPWLQTIEDLSSSDEDGVDGGIFRFRDLWGLTCKILFDVSCIANGLM
DEKLKGELGHEDLIVGLHDYGNQMQPNGRSEWEIGMINGDRNLKYSDVIPEYYMKHLL
ECRSLW"
gene complement(442958..444688)
/locus_tag="YLR152C"
/db_xref="GeneID:850845"
mRNA complement(442958..444688)
/locus_tag="YLR152C"
/product="hypothetical protein"
/transcript_id="NM_001182039.1"
/db_xref="GI:296146683"
/db_xref="GeneID:850845"
CDS complement(442958..444688)
/locus_tag="YLR152C"
/note="hypothetical protein; YLR152C is not an essential
gene"
/codon_start=1
/product="hypothetical protein"
/protein_id="NP_013253.1"
/db_xref="GI:6323181"
/db_xref="SGD:S000004142"
/db_xref="GeneID:850845"
/translation="MSLSLGAAIYIALKPIFKIYTIMLVGYLVAKFDIVSMENAKGIS
NMVVNAILPCLTFNKIVSNISWRDIKEIGVIILSAFILFVLGATGALFTTFATTVPKK
FFWGLIFAGFFPNISDLPIAYIQSMGNGSIFTAEEADKGVAYSCIFLFIQSFLMMNFG
MWRVVGLDFRDTKEPDSENITPSVSPAIDDRKLTEITKLPNITRPTNAYQSEDARSNS
DLSCNSITTNEMTPQAFYEGFTGYIKPYKESNGASHKFESDLPHAEIYRVSSTYSSPG
ALEFSRIDGSSLSYSRISKNSDGRSYRRKRKADMNELISKYSAAEKIRQGELDLSRPL
SLTEEVGSRNASIGNVHTGYTDESSIEEENCTNMATDGRGSLSFFIERHNLKWLQYFI
INCLRPASLGAILGIICALIPWVKACFVTTYVHVHKAPDGEPVLNFLMDFTEYIGNAC
VPLGLLLLGGTLARLEIKSLPPGFIKSALLMTCFRLIVIPIIGVLWVNKLYSIDWLDT
GIGKFDMILTWSMPSATAQVYFTAFYTPACGDHIQMNCLSVLFVMQYAILFITVAFVV
TYTLKVDLKV"
gene complement(445524..447575)
/gene="ACS2"
/locus_tag="YLR153C"
/db_xref="GeneID:850846"
mRNA complement(445524..447575)
/gene="ACS2"
/locus_tag="YLR153C"
/product="acetate--CoA ligase ACS2"
/transcript_id="NM_001182040.1"
/db_xref="GI:296146684"
/db_xref="GeneID:850846"
CDS complement(445524..447575)
/gene="ACS2"
/locus_tag="YLR153C"
/EC_number="6.2.1.1"
/note="Acetyl-coA synthetase isoform which, along with
Acs1p, is the nuclear source of acetyl-coA for histone
acetylation; mutants affect global transcription; required
for growth on glucose; expressed under anaerobic
conditions"
/codon_start=1
/product="acetate--CoA ligase ACS2"
/protein_id="NP_013254.1"
/db_xref="GI:6323182"
/db_xref="SGD:S000004143"
/db_xref="GeneID:850846"
/translation="MTIKEHKVVYEAHNVKALKAPQHFYNSQPGKGYVTDMQHYQEMY
QQSINEPEKFFDKMAKEYLHWDAPYTKVQSGSLNNGDVAWFLNGKLNASYNCVDRHAF
ANPDKPALIYEADDESDNKIITFGELLRKVSQIAGVLKSWGVKKGDTVAIYLPMIPEA
VIAMLAVARIGAIHSVVFAGFSAGSLKDRVVDANSKVVITCDEGKRGGKTINTKKIVD
EGLNGVDLVSRILVFQRTGTEGIPMKAGRDYWWHEEAAKQRTYLPPVSCDAEDPLFLL
YTSGSTGSPKGVVHTTGGYLLGAALTTRYVFDIHPEDVLFTAGDVGWITGHTYALYGP
LTLGTASIIFESTPAYPDYGRYWRIIQRHKATHFYVAPTALRLIKRVGEAEIAKYDTS
SLRVLGSVGEPISPDLWEWYHEKVGNKNCVICDTMWQTESGSHLIAPLAGAVPTKPGS
ATVPFFGINACIIDPVTGVELEGNDVEGVLAVKSPWPSMARSVWNHHDRYMDTYLKPY
PGHYFTGDGAGRDHDGYYWIRGRVDDVVNVSGHRLSTSEIEASISNHENVSEAAVVGI
PDELTGQTVVAYVSLKDGYLQNNATEGDAEHITPDNLRRELILQVRGEIGPFASPKTI
ILVRDLPRTRSGKIMRRVLRKVASNEAEQLGDLTTLANPEVVPAIISAVENQFFSQKK
K"
gene complement(447982..448314)
/gene="RNH203"
/locus_tag="YLR154C"
/db_xref="GeneID:850847"
mRNA complement(447982..448314)
/gene="RNH203"
/locus_tag="YLR154C"
/product="Rnh203p"
/transcript_id="NM_001182041.1"
/db_xref="GI:296146685"
/db_xref="GeneID:850847"
CDS complement(447982..448314)
/gene="RNH203"
/locus_tag="YLR154C"
/note="Ribonuclease H2 subunit, required for RNase H2
activity; related to human AGS3 that causes
Aicardi-Goutieres syndrome"
/codon_start=1
/product="Rnh203p"
/protein_id="NP_013255.1"
/db_xref="GI:6323183"
/db_xref="SGD:S000004144"
/db_xref="GeneID:850847"
/translation="MTKDAVNLDAYTVSFMPFYTEYQGPTEEFKDYKFEDTIYFRGKE
LKREKSATPSSSDNTTSNTFSNGAILSGNTITGKIVSVNNYEREGTDRNELARLQELI
SLIDVINQ"
gene complement(448650..448721)
/locus_tag="tQ(UUG)L"
/db_xref="GeneID:850848"
tRNA complement(448650..448721)
/locus_tag="tQ(UUG)L"
/product="tRNA-Gln"
/note="Glutamine tRNA (tRNA-Gln), predicted by tRNAscan-SE
analysis; thiolation of uridine at wobble position (34)
requires Ncs6p"
/db_xref="SGD:S000006699"
/db_xref="GeneID:850848"
LTR 448842..449028
/note="Ty1 LTR"
/db_xref="SGD:S000007084"
rep_origin 450485..450725
/note="ARS1216;
Autonomously Replicating Sequence"
/db_xref="SGD:S000118475"
gene complement(451575..458432)
/locus_tag="RDN37-1"
/db_xref="GeneID:9164931"
rRNA complement(451575..458432)
/locus_tag="RDN37-1"
/product="RDN37-1"
/note="35S ribosomal RNA (35S rRNA) transcript; encoded by
the RDN1 locus; processed into the 25S, 18S and 5.8S rRNAs
(represented by the RDN25, RDN18, and RDN58 loci)"
/db_xref="SGD:S000006486"
/db_xref="GeneID:9164931"
gene complement(451575..451785)
/locus_tag="ETS2-1"
/db_xref="GeneID:9164936"
rRNA complement(451575..451785)
/locus_tag="ETS2-1"
/product="ETS2-1"
/note="Non-coding region located adjacent to and
downstream of RDN25, transcribed as part of the 35S rRNA
precursor transcript; contains the primary rRNA
transcription termination site at +93 and a secondary
termination site between +211 and +250"
/db_xref="SGD:S000029718"
/db_xref="GeneID:9164936"
gene complement(451786..455181)
/locus_tag="RDN25-1"
/db_xref="GeneID:9164935"
rRNA complement(451786..455181)
/locus_tag="RDN25-1"
/product="RDN25-1"
/note="25S ribosomal RNA (25S rRNA), component of the
large (60S) ribosomal subunit; encoded in the rDNA repeat
(RDN1) as part of the 35S primary transcript"
/db_xref="SGD:S000006484"
/db_xref="GeneID:9164935"
STS 452543..452960
/standard_name="Pp_Pp7"
/db_xref="UniSTS:259708"
STS 452545..452997
/standard_name="PMC156610P1"
/db_xref="UniSTS:271418"
STS 452695..453070
/standard_name="PMC133845P2"
/db_xref="UniSTS:270669"
STS 452707..453001
/standard_name="PMC89798P1"
/db_xref="UniSTS:273611"
STS 452745..453001
/standard_name="PMC89798P2"
/db_xref="UniSTS:273612"
STS 452813..453060
/standard_name="PMC120649P1"
/db_xref="UniSTS:270380"
STS 454422..455029
/standard_name="PMC316820P1"
/db_xref="UniSTS:273051"
STS 454476..455113
/standard_name="PMC139893P1"
/db_xref="UniSTS:270904"
STS 454574..454981
/standard_name="PMC60231P1"
/db_xref="UniSTS:273400"
gene 454696..455070
/gene="TAR1"
/locus_tag="YLR154W-C"
/gene_synonym="YLR154W-A"
/db_xref="GeneID:1466405"
mRNA 454696..455070
/gene="TAR1"
/locus_tag="YLR154W-C"
/gene_synonym="YLR154W-A"
/product="Tar1p"
/transcript_id="NM_001184514.1"
/db_xref="GI:296146686"
/db_xref="GeneID:1466405"
CDS 454696..455070
/gene="TAR1"
/locus_tag="YLR154W-C"
/gene_synonym="YLR154W-A"
/note="Mitochondrial protein potentially involved in
regulation of respiratory metabolism; interacts
genetically with RPO41 and physically with Coq5p; encoded
within the 25S rRNA gene on the opposite strand"
/codon_start=1
/product="Tar1p"
/protein_id="NP_690845.1"
/db_xref="GI:23270399"
/db_xref="SGD:S000028422"
/db_xref="GeneID:1466405"
/translation="MRDSPTHKEQRAQNTMSDQMPFPFNNFTYFFTLFSKFFSSFHHC
TCSLSVSRQYLALDGIYHPLRAAFPNNSTLRRHFTKNRTPRHTGFSPSMTSCSKEHRQ
GTAPKLPSPNYNSGTEGTRFQI"
STS 454949..455134
/standard_name="G28482"
/db_xref="UniSTS:48320"
STS 455136..455976
/standard_name="PMC86038P1"
/db_xref="UniSTS:273512"
gene complement(455182..455413)
/locus_tag="ITS2-1"
/db_xref="GeneID:9164926"
rRNA complement(455182..455413)
/locus_tag="ITS2-1"
/product="ITS2-1"
/note="Non-coding region between RDN58 and RDN25, that is
transcribed as part of the 35S rRNA precursor transcript;
forms a stem-loop structure that is required for
processing of the precursor transcript"
/db_xref="SGD:S000029716"
/db_xref="GeneID:9164926"
gene complement(455414..455571)
/locus_tag="RDN58-1"
/db_xref="GeneID:9164934"
rRNA complement(455414..455571)
/locus_tag="RDN58-1"
/product="RDN58-1"
/note="5.8S ribosomal RNA (5.8S rRNA); component of the
large (60S) ribosomal subunit; encoded in the rDNA repeat
(RDN1) as part of the 35S primary transcript; 3' end
formation involves processing by the exosome complex while
5' end is generated by Kem1p and Rat1p"
/db_xref="SGD:S000006488"
/db_xref="GeneID:9164934"
STS 455522..455974
/standard_name="ITS"
/db_xref="UniSTS:275294"
gene complement(455572..455932)
/locus_tag="ITS1-1"
/db_xref="GeneID:9164938"
rRNA complement(455572..455932)
/locus_tag="ITS1-1"
/product="ITS1-1"
/note="Non-coding region between RDN58 and RDN18, that is
transcribed as part of the 35S rRNA precursor transcript;
excision during transcript maturation is coupled with
processing of the 3' external transcribed spacer (3'ETS)"
/db_xref="SGD:S000029715"
/db_xref="GeneID:9164938"
STS 455589..455685
/standard_name="PMC140538P1"
/db_xref="UniSTS:270941"
STS 455729..455928
/standard_name="PMC316945P1"
/db_xref="UniSTS:273065"
gene complement(455933..457732)
/locus_tag="RDN18-1"
/db_xref="GeneID:9164923"
rRNA complement(455933..457732)
/locus_tag="RDN18-1"
/product="RDN18-1"
/note="18S ribosomal RNA (18S rRNA); component of the
small (40S) ribosomal subunit; involved in codon
recognition by tRNAs or the release factor eRF1 (Sup45p);
encoded in the rDNA repeat (RDN1) as part of the 35S
primary transcript"
/db_xref="SGD:S000006482"
/db_xref="GeneID:9164923"
STS 456426..456720
/standard_name="PMC84574P1"
/db_xref="UniSTS:273448"
STS 456487..457457
/standard_name="PMC140342P1"
/db_xref="UniSTS:270933"
STS 456533..457329
/standard_name="PMC343294P1"
/db_xref="UniSTS:273189"
STS 456624..456974
/standard_name="PMC133845P3"
/db_xref="UniSTS:270670"
STS 456686..457188
/standard_name="PMC104890P1"
/db_xref="UniSTS:270115"
STS 456721..456797
/standard_name="PMC152246P1"
/db_xref="UniSTS:271203"
STS 456732..457417
/standard_name="PMC95223P1"
/db_xref="UniSTS:273623"
STS 456783..457302
/standard_name="PMC125238P1"
/db_xref="UniSTS:270483"
STS 456862..457276
/standard_name="PMC87142P1"
/db_xref="UniSTS:273581"
STS 457160..457713
/standard_name="PMC106412P1"
/db_xref="UniSTS:270119"
gene complement(457733..458432)
/locus_tag="ETS1-1"
/db_xref="GeneID:9164941"
rRNA complement(457733..458432)
/locus_tag="ETS1-1"
/product="ETS1-1"
/note="Non-coding region located immediately upstream of
RDN18, that is transcribed as part of the 35S rRNA
precursor transcript; contains an essential U3 snoRNA
binding site required for maturation of 18S rRNA"
/db_xref="SGD:S000029717"
/db_xref="GeneID:9164941"
STS 458142..459015
/standard_name="ha3107"
/db_xref="UniSTS:515651"
gene complement(458433..459675)
/locus_tag="NTS2-1"
/db_xref="GeneID:9164919"
rRNA complement(458433..459675)
/locus_tag="NTS2-1"
/product="NTS2-1"
/note="Nontranscribed region of the rDNA repeat, located
between RND5 and the 5'ETS; contains RNA polymerase I
termination site"
/db_xref="SGD:S000029329"
/db_xref="GeneID:9164919"
rep_origin 458991..459097
/note="ARS1200-1;
Chromosomal origin of bidirectional DNA replication; an
rDNA ARS is presumed to be present in each tandem rDNA
repeat, but fewer than one-third of the rDNA ARSs are
actually used as replication origins in a given S phase"
/db_xref="SGD:S000120636"
STS 459662..459788
/standard_name="PMC99952P1"
/db_xref="UniSTS:273710"
gene 459676..459796
/locus_tag="RDN5-1"
/db_xref="GeneID:9164945"
rRNA 459676..459796
/locus_tag="RDN5-1"
/product="RDN5-1"
/note="5S ribosomal RNA (5S rRNA); only complete sequence
of 6 repeated RDN5 alleles; able to support viability when
provided as sole form of 5S rRNA; component of the large
(60S) ribosomal subunit; localized to the nucleolus via
interaction with Rpl5p; may play a role in translational
frame fidelity; transcription is mediated by PolIII and
activated by TFIIIA and TFIIIE"
/db_xref="SGD:S000006479"
/db_xref="GeneID:9164945"
gene complement(459797..460711)
/locus_tag="NTS1-2"
/db_xref="GeneID:9164943"
rRNA complement(459797..460711)
/locus_tag="NTS1-2"
/product="NTS1-2"
/note="Non-transcribed region of the rDNA repeat located
between the 3' ETS and RDN5, required for rDNA repeat
expansion"
/db_xref="SGD:S000029714"
/db_xref="GeneID:9164943"
STS 459985..460291
/standard_name="PMC133845P1"
/db_xref="UniSTS:270668"
gene complement(460712..467569)
/locus_tag="RDN37-2"
/db_xref="GeneID:9164920"
rRNA complement(460712..467569)
/locus_tag="RDN37-2"
/product="RDN37-2"
/note="35S ribosomal RNA (35S rRNA) transcript; encoded by
the RDN1 locus; processed into the 25S, 18S and 5.8S rRNAs
(represented by the RDN25, RDN18, and RDN58 loci)"
/db_xref="SGD:S000006487"
/db_xref="GeneID:9164920"
gene complement(460712..460922)
/locus_tag="ETS2-2"
/db_xref="GeneID:9164942"
rRNA complement(460712..460922)
/locus_tag="ETS2-2"
/product="ETS2-2"
/note="Non-coding region located adjacent to RDN25,
transcribed as part of the 35S rRNA precursor transcript;
contains the primary rRNA transcription termination site
at +93 and a secondary termination site between +211 and
+250"
/db_xref="SGD:S000029713"
/db_xref="GeneID:9164942"
gene complement(460923..464318)
/locus_tag="RDN25-2"
/db_xref="GeneID:9164921"
rRNA complement(460923..464318)
/locus_tag="RDN25-2"
/product="RDN25-2"
/note="25S ribosomal RNA (25S rRNA), component of the
large (60S) ribosomal subunit; encoded in the rDNA repeat
(RDN1) as part of the 35S primary transcript"
/db_xref="SGD:S000006485"
/db_xref="GeneID:9164921"
STS 461680..462097
/standard_name="Pp_Pp7"
/db_xref="UniSTS:259708"
STS 461682..462134
/standard_name="PMC156610P1"
/db_xref="UniSTS:271418"
STS 461832..462207
/standard_name="PMC133845P2"
/db_xref="UniSTS:270669"
STS 461844..462138
/standard_name="PMC89798P1"
/db_xref="UniSTS:273611"
STS 461882..462138
/standard_name="PMC89798P2"
/db_xref="UniSTS:273612"
STS 461950..462197
/standard_name="PMC120649P1"
/db_xref="UniSTS:270380"
gene complement(462522..462671)
/locus_tag="YLR154C-G"
/db_xref="GeneID:1466409"
mRNA complement(462522..462671)
/locus_tag="YLR154C-G"
/product="hypothetical protein"
/transcript_id="NM_001184560.1"
/db_xref="GI:296146687"
/db_xref="GeneID:1466409"
CDS complement(462522..462671)
/locus_tag="YLR154C-G"
/note="hypothetical protein identified by fungal homology
comparisons and RT-PCR; this ORF is contained within
RDN25-2 and RDN37-2"
/codon_start=1
/product="hypothetical protein"
/protein_id="NP_878121.1"
/db_xref="GI:33438833"
/db_xref="SGD:S000028561"
/db_xref="GeneID:1466409"
/translation="MWRRRREPWEELSFLLNSLSPRNWFIRRWGLMAGRGQHLCWLRC
ACDGP"
STS 463559..464166
/standard_name="PMC316820P1"
/db_xref="UniSTS:273051"
STS 463613..464250
/standard_name="PMC139893P1"
/db_xref="UniSTS:270904"
STS 463711..464118
/standard_name="PMC60231P1"
/db_xref="UniSTS:273400"
STS 464086..464271
/standard_name="G28482"
/db_xref="UniSTS:48320"
STS 464273..465113
/standard_name="PMC86038P1"
/db_xref="UniSTS:273512"
gene complement(464319..464550)
/locus_tag="ITS2-2"
/db_xref="GeneID:9164930"
rRNA complement(464319..464550)
/locus_tag="ITS2-2"
/product="ITS2-2"
/note="Non-coding region between RDN58 and RDN25,
transcribed as part of the 35S rRNA precursor transcript;
forms a stem-loop structure required for processing of the
precursor transcript"
/db_xref="SGD:S000029712"
/db_xref="GeneID:9164930"
gene complement(464551..464708)
/locus_tag="RDN58-2"
/db_xref="GeneID:9164939"
rRNA complement(464551..464708)
/locus_tag="RDN58-2"
/product="RDN58-2"
/note="5.8S ribosomal RNA (5.8S rRNA); component of the
large (60S) ribosomal subunit; encoded in the rDNA repeat
(RDN1)"
/db_xref="SGD:S000006489"
/db_xref="GeneID:9164939"
STS 464659..465111
/standard_name="ITS"
/db_xref="UniSTS:275294"
gene complement(464709..465069)
/locus_tag="ITS1-2"
/db_xref="GeneID:9164940"
rRNA complement(464709..465069)
/locus_tag="ITS1-2"
/product="ITS1-2"
/note="Non-coding region between RDN58 and RDN18,
transcribed as part of the 35S rRNA precursor transcript;
excision during transcript maturation is coupled with
processing of the 3' external transcribed spacer (3' ETS)"
/db_xref="SGD:S000029709"
/db_xref="GeneID:9164940"
STS 464726..464822
/standard_name="PMC140538P1"
/db_xref="UniSTS:270941"
STS 464866..465065
/standard_name="PMC316945P1"
/db_xref="UniSTS:273065"
gene complement(465070..466869)
/locus_tag="RDN18-2"
/db_xref="GeneID:9164932"
rRNA complement(465070..466869)
/locus_tag="RDN18-2"
/product="RDN18-2"
/note="18S ribosomal RNA (18S rRNA); component of the
small (40S) ribosomal subunit; involved in codon
recognition by tRNAs or the release factor eRF1 (Sup45p);
encoded in the rDNA repeat (RDN1) as part of the 35S
primary transcript"
/db_xref="SGD:S000006483"
/db_xref="GeneID:9164932"
STS 465563..465857
/standard_name="PMC84574P1"
/db_xref="UniSTS:273448"
STS 465624..466594
/standard_name="PMC140342P1"
/db_xref="UniSTS:270933"
STS 465670..466466
/standard_name="PMC343294P1"
/db_xref="UniSTS:273189"
STS 465761..466111
/standard_name="PMC133845P3"
/db_xref="UniSTS:270670"
STS 465823..466325
/standard_name="PMC104890P1"
/db_xref="UniSTS:270115"
STS 465858..465934
/standard_name="PMC152246P1"
/db_xref="UniSTS:271203"
STS 465869..466554
/standard_name="PMC95223P1"
/db_xref="UniSTS:273623"
STS 465920..466439
/standard_name="PMC125238P1"
/db_xref="UniSTS:270483"
STS 465999..466413
/standard_name="PMC87142P1"
/db_xref="UniSTS:273581"
STS 466297..466850
/standard_name="PMC106412P1"
/db_xref="UniSTS:270119"
gene complement(466870..467569)
/locus_tag="ETS1-2"
/db_xref="GeneID:9164933"
rRNA complement(466870..467569)
/locus_tag="ETS1-2"
/product="ETS1-2"
/note="Non-coding region located immediately upstream of
RDN18, transcribed as part of the 35S rRNA precursor
transcript; contains an essential U3 snoRNA binding site
required for maturation of 18S rRNA"
/db_xref="SGD:S000029707"
/db_xref="GeneID:9164933"
STS 467279..468152
/standard_name="ha3107"
/db_xref="UniSTS:515651"
gene complement(467570..468812)
/locus_tag="NTS2-2"
/db_xref="GeneID:9164948"
rRNA complement(467570..468812)
/locus_tag="NTS2-2"
/product="NTS2-2"
/note="Non-transcribed region of the rDNA repeat, located
between RDN5 and the 5' ETS"
/db_xref="SGD:S000029706"
/db_xref="GeneID:9164948"
rep_origin 468128..468234
/note="ARS1200-2;
Chromosomal origin of bidirectional DNA replication; an
rDNA ARS is presumed to be present in each tandem rDNA
repeat, but fewer than one-third of the rDNA ARSs are
actually used as replication origins in a given S phase"
/db_xref="SGD:S000120655"
STS 468799..468925
/standard_name="PMC99952P1"
/db_xref="UniSTS:273710"
gene 468813..468931
/locus_tag="RDN5-2"
/db_xref="GeneID:9164928"
rRNA 468813..468931
/locus_tag="RDN5-2"
/product="RDN5-2"
/note="Variant 5S ribosomal rRNA (5S rRNA) gene; located
within the RDN1 locus; unable to support cell viability
when provided as sole source of 5S rRNA; identical in
sequence to variant alleles RDN5-3, RDN5-4, and RDN5-5"
/db_xref="SGD:S000006480"
/db_xref="GeneID:9164928"
gene complement(468827..468958)
/locus_tag="YLR154C-H"
/db_xref="GeneID:1466410"
mRNA complement(468827..468958)
/locus_tag="YLR154C-H"
/product="hypothetical protein"
/transcript_id="NM_001184564.1"
/db_xref="GI:296146697"
/db_xref="GeneID:1466410"
CDS complement(468827..468958)
/locus_tag="YLR154C-H"
/note="hypothetical protein identified by fungal homology
comparisons and RT-PCR; this ORF partially overlaps
RND5-2"
/codon_start=1
/product="hypothetical protein"
/protein_id="NP_878126.1"
/db_xref="GI:33438838"
/db_xref="SGD:S000028562"
/db_xref="GeneID:1466410"
/translation="MYSCAKKKTTAAPEFRVWSPTTLLGQALTSLTTVDRTGNGAFW"
gene complement(469317..470405)
/gene="ASP3-1"
/locus_tag="YLR155C"
/gene_synonym="ASP3"
/db_xref="GeneID:850850"
mRNA complement(469317..470405)
/gene="ASP3-1"
/locus_tag="YLR155C"
/gene_synonym="ASP3"
/product="asparaginase ASP3-1"
/transcript_id="NM_001182042.1"
/db_xref="GI:296146689"
/db_xref="GeneID:850850"
CDS complement(469317..470405)
/gene="ASP3-1"
/locus_tag="YLR155C"
/gene_synonym="ASP3"
/EC_number="3.5.1.1"
/note="Cell-wall L-asparaginase II involved in asparagine
catabolism; expression induced during nitrogen starvation;
ORF contains a short non-coding RNA that enhances
expression of full-length gene; likely arose in via
horizontal gene transfer from the wine yeast
Wickerhamomyces anomalus or a close relative; reference
strain S288C has four copies of ASP3"
/codon_start=1
/product="asparaginase ASP3-1"
/protein_id="NP_013256.1"
/db_xref="GI:6323184"
/db_xref="SGD:S000004145"
/db_xref="GeneID:850850"
/translation="MRSLNTLLLSLFVAMSSGAPLLKIREEKNSSLPSIKIFGTGGTI
ASKGSTSATTAGYSVGLTVNDLIEAVPSLAEKANLDYLQVSNVGSNSLNYTHLIPLYH
GISEALASDDYAGAVVTHGTDTMEETAFFLDLTINSEKPVCIAGAMRPATATSADGPM
NLYQAVSIAASEKSLGRGTMITLNDRIASGFWTTKMNANSLDTFRADEQGYLGYFSND
DVEFYYPPVKPNGWQFFDISNLTDPSEIPEVIILYSYQGLNPELIVKAVKDLGAKGIV
LAGSGAGSWTATGSIVNEQLYEEYGIPIVHSRRTADGTVPPDDAPEYAIGSGYLNPQK
SRILLQLCLYSGYGMDQIRSVFSGVYGG"
gene 472113..472457
/locus_tag="YLR156W"
/db_xref="GeneID:850851"
mRNA 472113..472457
/locus_tag="YLR156W"
/product="hypothetical protein"
/transcript_id="NM_001182043.1"
/db_xref="GI:296146690"
/db_xref="GeneID:850851"
CDS 472113..472457
/locus_tag="YLR156W"
/note="hypothetical protein; exhibits a two-hybrid
interaction with Jsn1p in a large-scale analysis"
/codon_start=1
/product="hypothetical protein"
/protein_id="NP_757337.1"
/db_xref="GI:26225099"
/db_xref="SGD:S000004146"
/db_xref="GeneID:850851"
/translation="MKFQYALAKEQLGSNSRSGVKKLISKHHWLPEYYFSDLSFSVVQ
QWDSRAIEKTTIISCMRPANQEIYPLRHCETLRSQPCSLFSSLYARSFQSSCTLHVAE
PSPGFHMYGCHT"
gene 472465..472583
/locus_tag="RDN5-3"
/db_xref="GeneID:9164924"
rRNA 472465..472583
/locus_tag="RDN5-3"
/product="RDN5-3"
/note="Variant 5S ribosomal RNA (5S rRNA) gene; located at
a site distal to the RDN1 locus; unable to support cell
viability when provided as sole source of 5S rRNA;
identical in sequence to variant alleles RDN5-2, RDN5-4,
and RDN5-5"
/db_xref="SGD:S000006481"
/db_xref="GeneID:9164924"
gene complement(472479..472610)
/locus_tag="YLR156C-A"
/db_xref="GeneID:1466411"
mRNA complement(472479..472610)
/locus_tag="YLR156C-A"
/product="hypothetical protein"
/transcript_id="NM_001184563.1"
/db_xref="GI:296146691"
/db_xref="GeneID:1466411"
CDS complement(472479..472610)
/locus_tag="YLR156C-A"
/note="hypothetical protein identified by fungal homology
comparisons and RT-PCR; this ORF partially overlaps
RND5-3"
/codon_start=1
/product="hypothetical protein"
/protein_id="NP_878123.1"
/db_xref="GI:33438835"
/db_xref="SGD:S000028564"
/db_xref="GeneID:1466411"
/translation="MYSCAKKKTTAAPEFRVWSPTTLLGQALTSLTTVDRTGNGAFW"
gene complement(472969..474057)
/gene="ASP3-2"
/locus_tag="YLR157C"
/gene_synonym="ASP3"
/db_xref="GeneID:850852"
mRNA complement(472969..474057)
/gene="ASP3-2"
/locus_tag="YLR157C"
/gene_synonym="ASP3"
/product="asparaginase ASP3-2"
/transcript_id="NM_001182044.1"
/db_xref="GI:296146692"
/db_xref="GeneID:850852"
CDS complement(472969..474057)
/gene="ASP3-2"
/locus_tag="YLR157C"
/gene_synonym="ASP3"
/EC_number="3.5.1.1"
/note="Cell-wall L-asparaginase II involved in asparagine
catabolism; expression induced during nitrogen starvation;
ORF contains a short non-coding RNA that enhances
expression of full-length gene; likely arose in via
horizontal gene transfer from the wine yeast
Wickerhamomyces anomalus or a close relative; reference
strain S288C has four copies of ASP3"
/codon_start=1
/product="asparaginase ASP3-2"
/protein_id="NP_013258.1"
/db_xref="GI:6323186"
/db_xref="SGD:S000004147"
/db_xref="GeneID:850852"
/translation="MRSLNTLLLSLFVAMSSGAPLLKIREEKNSSLPSIKIFGTGGTI
ASKGSTSATTAGYSVGLTVNDLIEAVPSLAEKANLDYLQVSNVGSNSLNYTHLIPLYH
GISEALASDDYAGAVVTHGTDTMEETAFFLDLTINSEKPVCIAGAMRPATATSADGPM
NLYQAVSIAASEKSLGRGTMITLNDRIASGFWTTKMNANSLDTFRADEQGYLGYFSND
DVEFYYPPVKPNGWQFFDISNLTDPSEIPEVIILYSYQGLNPELIVKAVKDLGAKGIV
LAGSGAGSWTATGSIVNEQLYEEYGIPIVHSRRTADGTVPPDDAPEYAIGSGYLNPQK
SRILLQLCLYSGYGMDQIRSVFSGVYGG"
gene 475764..475976
/locus_tag="YLR157W-D"
/gene_synonym="YLR157W-A"
/db_xref="GeneID:1466412"
mRNA 475764..475976
/locus_tag="YLR157W-D"
/gene_synonym="YLR157W-A"
/product="hypothetical protein"
/transcript_id="NM_001184608.1"
/db_xref="GI:296146693"
/db_xref="GeneID:1466412"
CDS 475764..475976
/locus_tag="YLR157W-D"
/gene_synonym="YLR157W-A"
/note="hypothetical protein; identified by gene-trapping,
microarray-based expression analysis, and genome-wide
homology searching"
/codon_start=1
/product="hypothetical protein"
/protein_id="NP_878124.1"
/db_xref="GI:33438836"
/db_xref="SGD:S000028677"
/db_xref="GeneID:1466412"
/translation="MKFQYALAKEQLGSNSRSGVKKLISKHHWLPEYYFSDLSFSVVQ
QWDSRAIEKTTIISCMRPANQEIYPL"
mobile_element complement(475976..481897)
/note="YLRCTy1-1; Ty1 element, LTR retrotransposon of the
Copia (Pseudoviridae) group; contains co-transcribed genes
TYA Gag and TYB Pol, encoding proteins involved in
structure and function of virus-like particles, flanked by
two direct repeats"
/mobile_element_type="retrotransposon:YLRCTy1-1"
/db_xref="SGD:S000007081"
LTR complement(475976..476310)
/note="Ty1 LTR"
/db_xref="SGD:S000007068"
gene complement(476333..481601)
/locus_tag="YLR157C-B"
/db_xref="GeneID:850853"
mRNA complement(join(<476333..480295,480297..>481601))
/locus_tag="YLR157C-B"
/transcript_id="NM_001184406.1"
/db_xref="GI:296146694"
/db_xref="GeneID:850853"
CDS complement(join(476333..480295,480297..481601))
/locus_tag="YLR157C-B"
/EC_number="2.7.7.49"
/EC_number="3.4.23.-"
/EC_number="3.1.26.4"
/EC_number="2.7.7.7"
/ribosomal_slippage
/note="Retrotransposon TYA Gag and TYB Pol genes;
transcribed/translated as one unit; polyprotein is
processed to make a nucleocapsid-like protein (Gag),
reverse transcriptase (RT), protease (PR), and integrase
(IN); similar to retroviral genes"
/codon_start=1
/product="gag-pol fusion protein"
/protein_id="NP_058169.1"
/db_xref="GI:7839185"
/db_xref="SGD:S000007374"
/db_xref="GeneID:850853"
/translation="MESQQLSQHSPISHGSACASVTSKEVHTNQDPLDVSASKTEECE
KASTKANSQQTTTPASSAVPENPHHASPQPASVPPPQNGPYPQQCMMTQNQANPSGWS
FYGHPSMIPYTPYQMSPMYFPPGPQSQFPQYPSSVGTPLSTPSPESGNTFTDSSSADS
DMTSTKKYVRPPPMLTSPNDFPNWVKTYIKFLQNSNLGGIIPTVNGKPVRQITDDELT
FLYNTFQIFAPSQFLPTWVKDILSVDYTDIMKILSKSIEKMQSDTQEANDIVTLANLQ
YNGSTPADAFETKVTNIIDRLNNNGIHINNKVACQLIMRGLSGEYKFLRYTRHRHLNM
TVAELFLDIHAIYEEQQGSRNSKPNYRRNLSDEKNDSRSYTNTTKPKVIARNPQKTNN
SKSKTARAHNVSTSNNSPSTDNDSISKSTTEPIQLNNKHDLHLGQELTESTVNHTNHS
DDELPGHLLLDSGASRTLIRSAHHIHSASSNPDINVVDAQKRNIPINAIGDLQFHFQD
NTKTSIKVLHTPNIAYDLLSLNELAAVDITACFTKNVLERSDGTVLAPIVKYGDFYWV
SKKYLLPSNISVPTINNVHTSESTRKYPYPFIHRMLAHANAPTIRYSLKNNTITYFNE
SDVDWSSAIDYQCPDCLIGKSTKHRHIKGSRLKYQNSYEPFQYLHTDIFGPVHNLPNS
APSYFISFTDETTKFRWVYPLHDRREDSILDVFTTILAFIKNQFQASVLVIQMDRGSE
YTNRTLHKFLEKNGITPCYTTTADSRAHGVAERLNRTLLDDCRTQLQCSGLPNHLWFS
AIEFSTIVRNSLASPKSKKSARQHAGLAGLDISTLLPFGQPVIVNDHNPNSKIHPRGI
PGYALHPSRNSYGYIIYLPSLKKTVDTTNYVILQGKESRLDQFNYDALTFDEDLNRLT
ASYHSFIASNEIQESNDLNIESDHDFQSDIELHPEQPRNVLSKAVSPTDSTPPSTHTE
DSKRVSKTNIRAPREVDPNISESNILPSKKRSSTPQISNIESTGSGGMHKLNVPLLAP
MSQSNTHESSHASKSKDFRHSDSYSENETNHTNVPISSTGGTNNKTVPQISDQETEKR
IIHRSPSIDASPPENNSSHNIVPIKTPTTVSEQNTEESIIADLPLPDLPPESPTEFPD
PFKELPPINSRQTNSSLGGIGDSNAYTTINSKKRSLEDNETEIKVSRDTWNTKNMRSL
EPPRSKKRIHLIAAVKAVKSIKPIRTTLRYDEAITYNKDIKEKEKYIEAYHKEVNQLL
KMKTWDTDEYYDRKEIDPKRVINSMFIFNKKRDGTHKARFVARGDIQHPDTYDSGMQS
NTVHHYALMTSLSLALDNNYYITQLDISSAYLYADIKEELYIRPPPHLGMNDKLIRLK
KSLYGLKQSGANWYETIKSYLIKQCGMEEVRGWSCVFKNSQVTICLFVDDMILFSKDL
NANKKIITTLKKQYDTKIINLGESDNEIQYDILGLEIKYQRGKYMKLGMENSLTEKIP
KLNVPLNPKGRKLSAPGQPGLYIDQDELEIDEDEYKEKVHEMQKLIGLASYVGYKFRF
DLLYYINTLAQHILFPSRQVLDMTYELIQFMWDTRDKQLIWHKNKPTEPDNKLVAISD
ASYGNQPYYKSQIGNIYLLNGKVIGGKSTKASLTCTSTTEAEIHAISESVPLLNNLSY
LIQELNKKPIIKGLLTDSRSTISIIKSTNEEKFRNRFFGTKAMRLRDEVSGNNLYVYY
IETKKNIADVMTKPLPIKTFKLLTNKWIH"
gene complement(480279..481601)
/locus_tag="YLR157C-A"
/db_xref="GeneID:850854"
mRNA complement(<480279..>481601)
/locus_tag="YLR157C-A"
/transcript_id="NM_001184405.1"
/db_xref="GI:296146695"
/db_xref="GeneID:850854"
CDS complement(480279..481601)
/locus_tag="YLR157C-A"
/note="Retrotransposon TYA Gag gene co-transcribed with
TYB Pol; translated as TYA or TYA-TYB polyprotein; Gag is
a nucleocapsid protein that is the structural constituent
of virus-like particles (VLPs); similar to retroviral Gag"
/codon_start=1
/product="gag protein"
/protein_id="NP_058170.1"
/db_xref="GI:7839184"
/db_xref="SGD:S000007373"
/db_xref="GeneID:850854"
/translation="MESQQLSQHSPISHGSACASVTSKEVHTNQDPLDVSASKTEECE
KASTKANSQQTTTPASSAVPENPHHASPQPASVPPPQNGPYPQQCMMTQNQANPSGWS
FYGHPSMIPYTPYQMSPMYFPPGPQSQFPQYPSSVGTPLSTPSPESGNTFTDSSSADS
DMTSTKKYVRPPPMLTSPNDFPNWVKTYIKFLQNSNLGGIIPTVNGKPVRQITDDELT
FLYNTFQIFAPSQFLPTWVKDILSVDYTDIMKILSKSIEKMQSDTQEANDIVTLANLQ
YNGSTPADAFETKVTNIIDRLNNNGIHINNKVACQLIMRGLSGEYKFLRYTRHRHLNM
TVAELFLDIHAIYEEQQGSRNSKPNYRRNLSDEKNDSRSYTNTTKPKVIARNPQKTNN
SKSKTARAHNVSTSNNSPSTDNDSISKSTTEPIQLNNKHDLHLRPGTY"
LTR complement(481563..481897)
/note="Ty1 LTR"
/db_xref="SGD:S000007069"
gene 481873..482037
/locus_tag="YLR157W-E"
/gene_synonym="YLR157W-B; YLR157W-C"
/db_xref="GeneID:1466413"
mRNA 481873..482037
/locus_tag="YLR157W-E"
/gene_synonym="YLR157W-B; YLR157W-C"
/product="hypothetical protein"
/transcript_id="NM_001184609.1"
/db_xref="GI:296146696"
/db_xref="GeneID:1466413"
CDS 481873..482037
/locus_tag="YLR157W-E"
/gene_synonym="YLR157W-B; YLR157W-C"
/note="hypothetical protein identified by gene-trapping,
microarray-based expression analysis, and genome-wide
homology searching; partially overlaps a Ty1 element"
/codon_start=1
/product="hypothetical protein"
/protein_id="NP_878125.1"
/db_xref="GI:33438837"
/db_xref="SGD:S000028678"
/db_xref="GeneID:1466413"
/translation="MIVDFYSNTLRHCETLRSQPCSLFSSLYARSFQSSCTLHVAEPS
PGFHMYGCHT"
gene 482045..482163
/locus_tag="RDN5-4"
/db_xref="GeneID:9164929"
rRNA 482045..482163
/locus_tag="RDN5-4"
/product="RDN5-4"
/note="Variant 5S ribosomal rRNA (5S rRNA) gene; located
at a site distal to the RDN1 locus; unable to support cell
viability when provided as sole source of 5S rRNA;
identical in sequence to variant alleles RDN5-2, RDN5-3,
and RDN5-5"
/db_xref="SGD:S000029708"
/db_xref="GeneID:9164929"
gene complement(482059..482190)
/locus_tag="YLR157C-C"
/db_xref="GeneID:1466414"
mRNA complement(482059..482190)
/locus_tag="YLR157C-C"
/product="hypothetical protein"
/transcript_id="NM_001184561.1"
/db_xref="GI:296146688"
/db_xref="GeneID:1466414"
CDS complement(482059..482190)
/locus_tag="YLR157C-C"
/note="hypothetical protein identified by fungal homology
comparisons and RT-PCR; this ORF partially overlaps
RND5-4"
/codon_start=1
/product="hypothetical protein"
/protein_id="NP_878122.1"
/db_xref="GI:33438834"
/db_xref="SGD:S000028565"
/db_xref="GeneID:1466414"
/translation="MYSCAKKKTTAAPEFRVWSPTTLLGQALTSLTTVDRTGNGAFW"
gene complement(482549..483637)
/gene="ASP3-3"
/locus_tag="YLR158C"
/gene_synonym="ASP3"
/db_xref="GeneID:850855"
mRNA complement(482549..483637)
/gene="ASP3-3"
/locus_tag="YLR158C"
/gene_synonym="ASP3"
/product="asparaginase ASP3-3"
/transcript_id="NM_001182045.1"
/db_xref="GI:296146698"
/db_xref="GeneID:850855"
CDS complement(482549..483637)
/gene="ASP3-3"
/locus_tag="YLR158C"
/gene_synonym="ASP3"
/EC_number="3.5.1.1"
/note="Cell-wall L-asparaginase II involved in asparagine
catabolism; expression induced during nitrogen starvation;
ORF contains a short non-coding RNA that enhances
expression of full-length gene; likely arose in via
horizontal gene transfer from the wine yeast
Wickerhamomyces anomalus or a close relative; reference
strain S288C has four copies of ASP3"
/codon_start=1
/product="asparaginase ASP3-3"
/protein_id="NP_013259.1"
/db_xref="GI:6323187"
/db_xref="SGD:S000004148"
/db_xref="GeneID:850855"
/translation="MRSLNTLLLSLFVAMSSGAPLLKIREEKNSSLPSIKIFGTGGTI
ASKGSTSATTAGYSVGLTVNDLIEAVPSLAEKANLDYLQVSNVGSNSLNYTHLIPLYH
GISEALASDDYAGAVVTHGTDTMEETAFFLDLTINSEKPVCIAGAMRPATATSADGPM
NLYQAVSIAASEKSLGRGTMITLNDRIASGFWTTKMNANSLDTFRADEQGYLGYFSND
DVEFYYPPVKPNGWQFFDISNLTDPSEIPEVIILYSYQGLNPELIVKAVKDLGAKGIV
LAGSGAGSWTATGSIVNEQLYEEYGIPIVHSRRTADGTVPPDDAPEYAIGSGYLNPQK
SRILLQLCLYSGYGMDQIRSVFSGVYGG"
gene 485345..485689
/locus_tag="YLR159W"
/db_xref="GeneID:850856"
mRNA 485345..485689
/locus_tag="YLR159W"
/product="hypothetical protein"
/transcript_id="NM_001182046.1"
/db_xref="GI:296146699"
/db_xref="GeneID:850856"
CDS 485345..485689
/locus_tag="YLR159W"
/note="hypothetical protein; YLR156W, YLR159W, and YLR161W
are three identical open reading frames encoded near the
ribosomal DNA region of chromosome 12"
/codon_start=1
/product="hypothetical protein"
/protein_id="NP_757338.1"
/db_xref="GI:26225100"
/db_xref="SGD:S000004149"
/db_xref="GeneID:850856"
/translation="MKFQYALAKEQLGSNSRSGVKKLISKHHWLPEYYFSDLSFSVVQ
QWDSRAIEKTTIISCMRPANQEIYPLRHCETLRSQPCSLFSSLYARSFQSSCTLHVAE
PSPGFHMYGCHT"
gene 485697..485815
/locus_tag="RDN5-5"
/db_xref="GeneID:9164946"
rRNA 485697..485815
/locus_tag="RDN5-5"
/product="RDN5-5"
/note="Variant 5S ribosomal rRNA (5S rRNA) gene; located
at a site distal to the RDN1 locus; unable to support cell
viability when provided as sole source of 5S rRNA;
identical in sequence to variant alleles RDN5-2, RDN5-3,
and RDN5-4"
/db_xref="SGD:S000029710"
/db_xref="GeneID:9164946"
gene complement(485711..485842)
/locus_tag="YLR159C-A"
/db_xref="GeneID:1466415"
mRNA complement(485711..485842)
/locus_tag="YLR159C-A"
/product="hypothetical protein"
/transcript_id="NM_001184565.1"
/db_xref="GI:296146700"
/db_xref="GeneID:1466415"
CDS complement(485711..485842)
/locus_tag="YLR159C-A"
/note="hypothetical protein identified by fungal homology
comparisons and RT-PCR; this ORF partially overlaps
RND5-5"
/codon_start=1
/product="hypothetical protein"
/protein_id="NP_878127.1"
/db_xref="GI:33438839"
/db_xref="SGD:S000028566"
/db_xref="GeneID:1466415"
/translation="MYSCAKKKTTAAPEFRVWSPTTLLGQALTSLTTVDRTGNGAFW"
gene complement(486201..487289)
/gene="ASP3-4"
/locus_tag="YLR160C"
/gene_synonym="ASP3"
/db_xref="GeneID:850857"
mRNA complement(486201..487289)
/gene="ASP3-4"
/locus_tag="YLR160C"
/gene_synonym="ASP3"
/product="asparaginase ASP3-4"
/transcript_id="NM_001182047.1"
/db_xref="GI:296146701"
/db_xref="GeneID:850857"
CDS complement(486201..487289)
/gene="ASP3-4"
/locus_tag="YLR160C"
/gene_synonym="ASP3"
/EC_number="3.5.1.1"
/note="Cell-wall L-asparaginase II involved in asparagine
catabolism; expression induced during nitrogen starvation;
ORF contains a short non-coding RNA that enhances
expression of full-length gene; likely arose in via
horizontal gene transfer from the wine yeast
Wickerhamomyces anomalus or a close relative; reference
strain S288C has four copies of ASP3"
/codon_start=1
/product="asparaginase ASP3-4"
/protein_id="NP_013261.1"
/db_xref="GI:6323189"
/db_xref="SGD:S000004150"
/db_xref="GeneID:850857"
/translation="MRSLNTLLLSLFVAMSSGAPLLKIREEKNSSLPSIKIFGTGGTI
ASKGSTSATTAGYSVGLTVNDLIEAVPSLAEKANLDYLQVSNVGSNSLNYTHLIPLYH
GISEALASDDYAGAVVTHGTDTMEETAFFLDLTINSEKPVCIAGAMRPATATSADGPM
NLYQAVSIAASEKSLGRGTMITLNDRIASGFWTTKMNANSLDTFRADEQGYLGYFSND
DVEFYYPPVKPNGWQFFDISNLTDPSEIPEVIILYSYQGLNPELIVKAVKDLGAKGIV
LAGSGAGSWTATGSIVNEQLYEEYGIPIVHSRRTADGTVPPDDAPEYAIGSGYLNPQK
SRILLQLCLYSGYGMDQIRSVFSGVYGG"
gene 488997..489341
/locus_tag="YLR161W"
/db_xref="GeneID:850858"
mRNA 488997..489341
/locus_tag="YLR161W"
/product="hypothetical protein"
/transcript_id="NM_001182048.1"
/db_xref="GI:296146702"
/db_xref="GeneID:850858"
CDS 488997..489341
/locus_tag="YLR161W"
/note="hypothetical protein; YLR156W, YLR159W, and YLR161W
are three identical open reading frames encoded near the
ribosomal DNA region of chromosome 12"
/codon_start=1
/product="hypothetical protein"
/protein_id="NP_757339.1"
/db_xref="GI:26225101"
/db_xref="SGD:S000004151"
/db_xref="GeneID:850858"
/translation="MKFQYALAKEQLGSNSRSGVKKLISKHHWLPEYYFSDLSFSVVQ
QWDSRAIEKTTIISCMRPANQEIYPLRHCETLRSQPCSLFSSLYARSFQSSCTLHVAE
PSPGFHMYGCHT"
gene 489349..489469
/locus_tag="RDN5-6"
/db_xref="GeneID:9164918"
rRNA 489349..489469
/locus_tag="RDN5-6"
/product="RDN5-6"
/note="Variant 5S ribosomal rRNA (5S rRNA) gene; located
at a site distal to the RDN1 locus"
/db_xref="SGD:S000029711"
/db_xref="GeneID:9164918"
gene 489573..489929
/locus_tag="YLR162W"
/db_xref="GeneID:850859"
mRNA 489573..489929
/locus_tag="YLR162W"
/product="hypothetical protein"
/transcript_id="NM_001182049.1"
/db_xref="GI:296146703"
/db_xref="GeneID:850859"
CDS 489573..489929
/locus_tag="YLR162W"
/note="hypothetical protein; overexpression confers
resistance to the antimicrobial peptide MiAMP1 and causes
growth arrest, apoptosis, and increased sensitivity to
cobalt chloride"
/codon_start=1
/product="hypothetical protein"
/protein_id="NP_013263.1"
/db_xref="GI:6323191"
/db_xref="SGD:S000004152"
/db_xref="GeneID:850859"
/translation="MQHTLTRTASLPERSSSAHSAATALPALRRPPDSCETLVPLLCI
FWFVFVSMSPLPPARANKSDNKGLISADRNNKATLLLTIPRCTSKSYTNDLSPLKMTL
LSAGKHPRPFRQEHRC"
gene 490406..490594
/gene="RRT15"
/locus_tag="YLR162W-A"
/db_xref="GeneID:1466416"
mRNA 490406..490594
/gene="RRT15"
/locus_tag="YLR162W-A"
/product="Rrt15p"
/transcript_id="NM_001184566.1"
/db_xref="GI:296146704"
/db_xref="GeneID:1466416"
CDS 490406..490594
/gene="RRT15"
/locus_tag="YLR162W-A"
/note="hypothetical protein identified by fungal homology
comparisons and RT-PCR; identified in a screen for mutants
with decreased levels of rDNA transcription"
/codon_start=1
/product="Rrt15p"
/protein_id="NP_878128.1"
/db_xref="GI:33438840"
/db_xref="SGD:S000028567"
/db_xref="GeneID:1466416"
/translation="MVCIHTENQNQGDFYPFVLLEISVLHESPLGHLRYRLTDVPPQP
NSPGEIYCFYINCIMNRR"
gene complement(491866..493254)
/gene="MAS1"
/locus_tag="YLR163C"
/gene_synonym="MIF1"
/db_xref="GeneID:850860"
mRNA complement(491866..493254)
/gene="MAS1"
/locus_tag="YLR163C"
/gene_synonym="MIF1"
/product="Mas1p"
/transcript_id="NM_001182050.1"
/db_xref="GI:296146705"
/db_xref="GeneID:850860"
CDS complement(491866..493254)
/gene="MAS1"
/locus_tag="YLR163C"
/gene_synonym="MIF1"
/EC_number="3.4.24.64"
/note="Smaller subunit of the mitochondrial processing
protease (MPP), essential processing enzyme that cleaves
the N-terminal targeting sequences from mitochondrially
imported proteins"
/codon_start=1
/product="Mas1p"
/protein_id="NP_013264.1"
/db_xref="GI:6323192"
/db_xref="SGD:S000004153"
/db_xref="GeneID:850860"
/translation="MFSRTASKFRNTRRLLSTISSQIPGTRTSKLPNGLTIATEYIPN
TSSATVGIFVDAGSRAENVKNNGTAHFLEHLAFKGTQNRSQQGIELEIENIGSHLNAY
TSRENTVYYAKSLQEDIPKAVDILSDILTKSVLDNSAIERERDVIIRESEEVDKMYDE
VVFDHLHEITYKDQPLGRTILGPIKNIKSITRTDLKDYITKNYKGDRMVLAGAGAVDH
EKLVQYAQKYFGHVPKSESPVPLGSPRGPLPVFCRGERFIKENTLPTTHIAIALEGVS
WSAPDYFVALATQAIVGNWDRAIGTGTNSPSPLAVAASQNGSLANSYMSFSTSYADSG
LWGMYIVTDSNEHNVQLIVNEILKEWKRIKSGKISDAEVNRAKAQLKAALLLSLDGST
AIVEDIGRQVVTTGKRLSPEEVFEQVDKITKDDIIMWANYRLQNKPVSMVALGNTSTV
PNVSYIEEKLNQ"
gene 493883..494389
/gene="SHH4"
/locus_tag="YLR164W"
/db_xref="GeneID:850861"
mRNA 493883..494389
/gene="SHH4"
/locus_tag="YLR164W"
/product="protein SHH4"
/transcript_id="NM_001182051.1"
/db_xref="GI:296146706"
/db_xref="GeneID:850861"
CDS 493883..494389
/gene="SHH4"
/locus_tag="YLR164W"
/note="Mitochondrial inner membrane hypothetical protein;
similar to Tim18p and Sdh4p; a fraction copurifies with
Sdh3p, but Shh4p is neither a stoichiometric subunit of
succinate dehydrogenase nor of the TIM22 translocase;
expression induced by nitrogen limitation in a GLN3,
GAT1-dependent manner"
/codon_start=1
/product="protein SHH4"
/protein_id="NP_013265.1"
/db_xref="GI:6323193"
/db_xref="SGD:S000004154"
/db_xref="GeneID:850861"
/translation="MSSTKFLKPLCRIRAFHTSIARSFTIPFLPKIPQKPGGVSGTAN
DSSYMPPESRAQGSYHWIVERGLSLAVLPLIAVPLVTTGPISTFTDTFLSLVLLGHCH
IGFQSCIIDYISERVYGKVHHYAMYLLSLGSFLSFVGIYKLESQEAGLIASLKSLWDN
KPVEKKRQ"
gene complement(494494..495258)
/gene="PUS5"
/locus_tag="YLR165C"
/db_xref="GeneID:850862"
mRNA complement(494494..495258)
/gene="PUS5"
/locus_tag="YLR165C"
/product="pseudouridine synthase PUS5"
/transcript_id="NM_001182052.1"
/db_xref="GI:296146707"
/db_xref="GeneID:850862"
CDS complement(494494..495258)
/gene="PUS5"
/locus_tag="YLR165C"
/EC_number="5.4.99.-"
/note="Pseudouridine synthase, catalyzes only the
formation of pseudouridine (Psi)-2819 in mitochondrial 21S
rRNA; not essential for viability"
/codon_start=1
/product="pseudouridine synthase PUS5"
/protein_id="NP_013266.1"
/db_xref="GI:6323194"
/db_xref="SGD:S000004155"
/db_xref="GeneID:850862"
/translation="MSLKKQIPIIFENTHYFIVNKPPGIPSQPPDCRTWGRTHPNLDP
TPLLERFKAIYYSHREVELCRTVHRLDHCVTGGMLIAKTKDGSVKFSRFLQKGGNNGY
KLQRKYVAIVESSGRFNKPNNYEIKYGPKYNFLISHGGREITKFKEVDENCIVLQLVT
GKKHQIRNHVSQILNQPILNDKRHGSTVNFPELFNDQIALHSACIITKIGLQTKTHLI
PMEHNNTGQLWSRKYVNEEGEFTLPIKEVLLENWDQ"
gene complement(495429..498044)
/gene="SEC10"
/locus_tag="YLR166C"
/db_xref="GeneID:850863"
mRNA complement(495429..498044)
/gene="SEC10"
/locus_tag="YLR166C"
/product="Sec10p"
/transcript_id="NM_001182053.1"
/db_xref="GI:296146708"
/db_xref="GeneID:850863"
CDS complement(495429..498044)
/gene="SEC10"
/locus_tag="YLR166C"
/note="Essential 100kDa subunit of the exocyst complex
(Sec3p, Sec5p, Sec6p, Sec8p, Sec10p, Sec15p, Exo70p, and
Exo84p), which has the essential function of mediating
polarized targeting of secretory vesicles to active sites
of exocytosis"
/codon_start=1
/product="Sec10p"
/protein_id="NP_013267.1"
/db_xref="GI:6323195"
/db_xref="SGD:S000004156"
/db_xref="GeneID:850863"
/translation="MNSLYELDPKWKKLLKTDNFLGGLTVNEFVQELSKDHRNDVLID
ANTKNLPTNEKDQDAIREAIWKQLDPKPYIRTFESTLKELKNLNEETLNKRQYFSEQV
ATQEVIHSENVIKLSKDLHTTLLTFDKLDDRLTNVTQVVSPLGDKLETAIKKKQNYIQ
SVELIRRYNDFYSMGKSDIVEQLRLSKNWKLNLKSVKLMKNLLILSSKLETSSIPKTI
NTKLVIEKYSEMMENELLENFNSAYRENNFTKLNEIAIILNNFNGGVNVIQSFINQHD
YFIDTKQIDLENEFENVFIKNVKFKEQLIDFENHSVIIETSMQNLINDVETVIKNESK
IVKRVFEEKATHVIQLFIQRVFAQKIEPRFEVLLRNSLSISNLAYVRILHGLFTLFGK
FTKSLIDYFQLLEIDDSNQILSTTLEQCFADLFSHYLYDRSKYFGIEKRSLEAILVDM
TSKFTVNYDKEINKRVLLDKYKEKLSTNVDAFMHSPRGNTHSRQDSTSRSKLSQFNSF
LKTHLDKDHLSLNRTNTLSDSFNNSSSSTQYDVANNSSSLVNSSFTASDIDNSPNSPA
NYSLNDVDSMLKCVVESTARVMELIPNKAHLYILEILKIMFLGIVDSYMEIALEVAYW
KICKVDINKTAGVVNLNFLKFISMSTEILDLLSISIKSIFLPLLNNSPEIKAQIIEMT
NSQIQKMEILINIILQETITVISTKFSAILCKQKKKDFVPKSQELLDQDTLPAIEIVN
ILNLIFEQSSKFLKGKNLQTFLTLIGEELYGLLLSHYSHFQVNSIGGVVVTKDIIGYQ
TAIEDWGVASLIDKFATLRELANLFTVQPELLESLTKEGHLADIGRDIIQSYISNRED
FNHDNFINSVKLNFR"
gene 498947..499405
/gene="RPS31"
/locus_tag="YLR167W"
/gene_synonym="RPS37; UBI3"
/db_xref="GeneID:850864"
mRNA 498947..499405
/gene="RPS31"
/locus_tag="YLR167W"
/gene_synonym="RPS37; UBI3"
/product="ubiquitin-ribosomal 40S subunit protein S31
fusion protein"
/transcript_id="NM_001182054.1"
/db_xref="GI:296146709"
/db_xref="GeneID:850864"
CDS 498947..499405
/gene="RPS31"
/locus_tag="YLR167W"
/gene_synonym="RPS37; UBI3"
/note="Fusion protein cleaved to yield ribosomal protein
S31 and ubiquitin; ubiquitin may facilitate assembly of
the ribosomal protein into ribosomes; interacts
genetically with translation factor eIF2B; homologous to
mammalian ribosomal protein S27A, no bacterial homolog"
/codon_start=1
/product="ubiquitin-ribosomal 40S subunit protein S31
fusion protein"
/protein_id="NP_013268.1"
/db_xref="GI:6323196"
/db_xref="SGD:S000004157"
/db_xref="GeneID:850864"
/translation="MQIFVKTLTGKTITLEVESSDTIDNVKSKIQDKEGIPPDQQRLI
FAGKQLEDGRTLSDYNIQKESTLHLVLRLRGGGKKRKKKVYTTPKKIKHKHKKVKLAV
LSYYKVDAEGKVTKLRRECSNPTCGAGVFLANHKDRLYCGKCHSVYKVNA"
gene complement(499578..500270)
/gene="UPS2"
/locus_tag="YLR168C"
/gene_synonym="AIM30; GEP1; MSF1; MSF1'"
/db_xref="GeneID:850865"
mRNA complement(499578..500270)
/gene="UPS2"
/locus_tag="YLR168C"
/gene_synonym="AIM30; GEP1; MSF1; MSF1'"
/product="Ups2p"
/transcript_id="NM_001182055.1"
/db_xref="GI:296146710"
/db_xref="GeneID:850865"
CDS complement(499578..500270)
/gene="UPS2"
/locus_tag="YLR168C"
/gene_synonym="AIM30; GEP1; MSF1; MSF1'"
/note="Mitochondrial protein involved in phospholipid
metabolism; localizes to the intermembrane space; has a
role in regulation of phospholipid metabolism by
inhibiting conversion of phosphatidylethanolamine to
phosphatidylcholine; null mutant has defects in
mitochondrial morphology; similar to Ups1p, Ups3p and to
human PRELI"
/codon_start=1
/product="Ups2p"
/protein_id="NP_013269.1"
/db_xref="GI:6323197"
/db_xref="SGD:S000004158"
/db_xref="GeneID:850865"
/translation="MKLFQNSYDFNYPWDQVTAANWKKYPNEISTHVIAVDVLRRELK
DQGKVLVTERLITVKQGVPKWIMMMLGGTNMSHVREVSVVDLNKKSLTMRSCNLTMCN
LLKVYETVTYSPHPDDSANKTLFQQEAQITAYGSIRKLCNKMEDWSVQRFCENAKKGK
MGFDAVLQVFSENWEKHVDDLSNQLVSKVNETMEDVKISAGTLLKGTERSGRTILQQN
IDLFRDAYNHEN"
gene complement(500579..501049)
/gene="APS1"
/locus_tag="YLR170C"
/gene_synonym="YAP19"
/db_xref="GeneID:850868"
mRNA complement(500579..501049)
/gene="APS1"
/locus_tag="YLR170C"
/gene_synonym="YAP19"
/product="Aps1p"
/transcript_id="NM_001182057.1"
/db_xref="GI:296146711"
/db_xref="GeneID:850868"
CDS complement(500579..501049)
/gene="APS1"
/locus_tag="YLR170C"
/gene_synonym="YAP19"
/note="Small subunit of the clathrin-associated adaptor
complex AP-1, which is involved in protein sorting at the
trans-Golgi network; homolog of the sigma subunit of the
mammalian clathrin AP-1 complex"
/codon_start=1
/product="Aps1p"
/protein_id="NP_013271.1"
/db_xref="GI:6323200"
/db_xref="SGD:S000004160"
/db_xref="GeneID:850868"
/translation="MTQLKYLLLVSRQGKIRLKKWYTAMSAGEKAKIVKDLTPTILAR
KPKMCNIIEYNDHKVVYKRYASLYFIVGMTPDVDNELLTLEIIHRFVETMDTYFGNVC
ELDIIFNFSKVYDILNEMIMCDGSIAESSRKEVLHHVTVMDTMESNDNLERVLS"
gene complement(501260..502162)
/gene="DPH5"
/locus_tag="YLR172C"
/db_xref="GeneID:850869"
mRNA complement(501260..502162)
/gene="DPH5"
/locus_tag="YLR172C"
/product="diphthine synthase"
/transcript_id="NM_001182059.1"
/db_xref="GI:296146712"
/db_xref="GeneID:850869"
CDS complement(501260..502162)
/gene="DPH5"
/locus_tag="YLR172C"
/EC_number="2.1.1.98"
/note="Methyltransferase required for synthesis of
diphthamide, which is a modified histidine residue of
translation elongation factor 2 (Eft1p or Eft2p); not
essential for viability; GFP-Dph5p fusion protein
localizes to the cytoplasm"
/codon_start=1
/product="diphthine synthase"
/protein_id="NP_013273.1"
/db_xref="GI:6323201"
/db_xref="SGD:S000004162"
/db_xref="GeneID:850869"
/translation="MLYLIGLGLSYKSDITVRGLEAIKKCSRVYLEHYTSILMAASQE
ELESYYGKEIILADRELVETGSKQILNNADKEDVAFLVVGDPFGATTHTDLVLRAKRE
AIPVEIIHNASVMNAVGACGLQLYNFGQTVSMVFFTDNWRPDSWYDKIWENRKIGLHT
LVLLDIKVKEQSIENMARGRLIYEPPRYMSIAQCCEQLLEIEEKRGTKAYTPDTPAVA
ISRLGSSSQSFKSGTISELANYDSGEPLHSLVILGRQCHELELEYLLEFADDKEKFGK
DVANDQEYFKPAAWVPPTEDDSDE"
gene 502421..504247
/locus_tag="YLR173W"
/db_xref="GeneID:850870"
mRNA 502421..504247
/locus_tag="YLR173W"
/product="hypothetical protein"
/transcript_id="NM_001182060.1"
/db_xref="GI:296146713"
/db_xref="GeneID:850870"
CDS 502421..504247
/locus_tag="YLR173W"
/codon_start=1
/product="hypothetical protein"
/protein_id="NP_013274.1"
/db_xref="GI:6323202"
/db_xref="SGD:S000004163"
/db_xref="GeneID:850870"
/translation="MHTNSPLRADNQDLETQPLLRPNTEESQLLNDEVRINVANETLI
KSRWRSIKCLIIYLLGIVLLSFFGVSIVQYIRGHVPPTDVIEKNLVQVTNFKLVEFQL
DGWKDNMGSDLNNDTGKYLQVSIHSQIWFDYDKWPGTENDSDARSQRDWIRYINEKVL
KTICIDLNNVTTFDGDLVFKNKLGDVVGMEPICFNLAHRQINNLQFKILVKPSIWKIV
KVLKKFWNRDFESLNIKSNLDMTIFKRKFGTRFNLLKLNDEILDWKDIIDWEKISATP
LRMIQNMIDGISLQGFTLRDSSSDGFHADMRLNPITILGGVDWLHLPPGTSIPFINWE
IKLPDCNGEPAIAIPTLSCFNEPINLHHDKDNIVVCLQNEIEGPLPDELLYQECPQNS
LTPMSQIVNAVLNQNETVTFAARGHVLEDGIDNNSLIPADMLEDIFQEASFIPITTNA
TFNSSELIQEFQINDLQLRWAARKKLSLVGTFLGFFDLSFYETHQQDRVRIDTIRGQI
DLYHNDINFLNLPMKQWINSSSHILHDEDTGNTQMKLQFDLENDDMEVVNSLELTRTL
NEILFQGFTVIHFNATIDASLTTALGPWVLTGLAGEGDTLVT"
gene 504591..505829
/gene="IDP2"
/locus_tag="YLR174W"
/db_xref="GeneID:850871"
mRNA 504591..505829
/gene="IDP2"
/locus_tag="YLR174W"
/product="isocitrate dehydrogenase (NADP(+)) IDP2"
/transcript_id="NM_001182061.1"
/db_xref="GI:296146714"
/db_xref="GeneID:850871"
CDS 504591..505829
/gene="IDP2"
/locus_tag="YLR174W"
/EC_number="1.1.1.42"
/note="Cytosolic NADP-specific isocitrate dehydrogenase,
catalyzes oxidation of isocitrate to alpha-ketoglutarate;
levels are elevated during growth on non-fermentable
carbon sources and reduced during growth on glucose"
/codon_start=1
/product="isocitrate dehydrogenase (NADP(+)) IDP2"
/protein_id="NP_013275.1"
/db_xref="GI:6323203"
/db_xref="SGD:S000004164"
/db_xref="GeneID:850871"
/translation="MTKIKVANPIVEMDGDEQTRIIWHLIRDKLVLPYLDVDLKYYDL
SVEYRDQTNDQVTVDSATATLKYGVAVKCATITPDEARVEEFHLKKMWKSPNGTIRNI
LGGTVFREPIIIPRIPRLVPQWEKPIIIGRHAFGDQYKATDVIVPEEGELRLVYKSKS
GTHDVDLKVFDYPEHGGVAMMMYNTTDSIEGFAKASFELAIERKLPLYSTTKNTILKK
YDGKFKDVFEAMYARSYKEKFESLGIWYEHRLIDDMVAQMLKSKGGYIIAMKNYDGDV
ESDIVAQGFGSLGLMTSVLITPDGKTFESEAAHGTVTRHFRQHQQGKETSTNSIASIF
AWTRGIIQRGKLDNTPDVVKFGQILESATVNTVQEDGIMTKDLALILGKSERSAYVTT
EEFIDAVESRLKKEFEAAAL"
gene 506134..507585
/gene="CBF5"
/locus_tag="YLR175W"
/db_xref="GeneID:850872"
mRNA 506134..507585
/gene="CBF5"
/locus_tag="YLR175W"
/product="pseudouridine synthase CBF5"
/transcript_id="NM_001182062.1"
/db_xref="GI:296146715"
/db_xref="GeneID:850872"
CDS 506134..507585
/gene="CBF5"
/locus_tag="YLR175W"
/EC_number="5.4.99.-"
/note="Pseudouridine synthase catalytic subunit of box
H/ACA small nucleolar ribonucleoprotein particles
(snoRNPs), acts on both large and small rRNAs and on snRNA
U2; mutations in human ortholog dyskerin cause the
disorder dyskeratosis congenita"
/codon_start=1
/product="pseudouridine synthase CBF5"
/protein_id="NP_013276.1"
/db_xref="GI:6323204"
/db_xref="SGD:S000004165"
/db_xref="GeneID:850872"
/translation="MSKEDFVIKPEAAGASTDTSEWPLLLKNFDKLLVRSGHYTPIPA
GSSPLKRDLKSYISSGVINLDKPSNPSSHEVVAWIKRILRCEKTGHSGTLDPKVTGCL
IVCIDRATRLVKSQQGAGKEYVCIVRLHDALKDEKDLGRSLENLTGALFQRPPLISAV
KRQLRVRTIYESNLIEFDNKRNLGVFWASCEAGTYMRTLCVHLGMLLGVGGHMQELRR
VRSGALSENDNMVTLHDVMDAQWVYDNTRDESYLRSIIQPLETLLVGYKRIVVKDSAV
NAVCYGAKLMIPGLLRYEEGIELYDEIVLITTKGEAIAVAIAQMSTVDLASCDHGVVA
SVKRCIMERDLYPRRWGLGPVAQKKKQMKADGKLDKYGRVNENTPEQWKKEYVPLDNA
EQSTSSSQETKETEEEPKKAKEDSLIKEVETEKEEVKEDDSKKEKKEKKDKKEKKEKK
EKKDKKEKKEKKEKKRKSEDGDSEEKKSKKSKK"
gene complement(507797..510232)
/gene="RFX1"
/locus_tag="YLR176C"
/gene_synonym="CRT1"
/db_xref="GeneID:850873"
mRNA complement(507797..510232)
/gene="RFX1"
/locus_tag="YLR176C"
/gene_synonym="CRT1"
/product="Rfx1p"
/transcript_id="NM_001182063.1"
/db_xref="GI:296146716"
/db_xref="GeneID:850873"
CDS complement(507797..510232)
/gene="RFX1"
/locus_tag="YLR176C"
/gene_synonym="CRT1"
/note="Major transcriptional repressor of
DNA-damage-regulated genes, recruits repressors Tup1p and
Cyc8p to their promoters; involved in DNA damage and
replication checkpoint pathway; similar to a family of
mammalian DNA binding RFX1-4 proteins"
/codon_start=1
/product="Rfx1p"
/protein_id="NP_013277.1"
/db_xref="GI:6323205"
/db_xref="SGD:S000004166"
/db_xref="GeneID:850873"
/translation="MVIFKERKPTENLFTRKIPAKYFIFSPSFLSVHYFEFYLPMSGD
NNIEPTSRGSNDNSNGPSNGSSVNSNRYSLNAPKYSSQPPPASHTYLPPMSVNIPPIA
SKSSSIYSLLHQSSPRPETPNPILPPLIGSGPGSHKPSPTPTQPPAQPATQRQPATYS
VYPASISLNRSNSSAYPLSFKSEETLNNNPPTAAKRTNTFPSIPSSTKKQKTSQEKRI
SSISRRNTQEIIAKQIAENNKSKTIEEYAQIVKHAEIKVLSMDSQNTSKAALQLAEQN
RERERQVFALLWLMKNCKSQHDSYVPRGKIFAQYASSCSQNNLKPLSQASLGKLIRTV
FPDLTTRRLGMRGQSKYHYCGLKLTVNESGSVSLNNNNASLSLVHNNDPISPLSSPSP
SSPSPQVPNVSSPFSLNRKSLSRTGSPVKQSSNDNPNEPELESQHPNETEANKLDSLP
PAANNPTGTLSSDELTFTHDLIEKVFNCNDKLSDNYNTQILSNTEHPLLTSYKLDFPK
IPAGVLPTDTDSDVISSLESLYHIHCNSVYECIKFLKSDNISNALFFSNSNSISPTMF
NLFISEPLIDWVTKCDLITYTGLIKFFSQFIIHSNEISDSIIQKLESMIKLLPEQINK
AVLELPKALVQRKLSIINNFTKLVKKLIKLLKFILNFLKSFPIFKSGMNNDWKNIVNL
DDILEMMINEDDTNSETNTIMQHLQGFCQVFVTKFLNSSMSVSNDPSVSIECKSLNEM
IKDFCSFISLQSKFSCLKLIDCSTRFRNAIIGDISLKSNENLLSWLFLNNVMGQLLNY
CFEVMKFVNGLKV"
gene 511054..512940
/locus_tag="YLR177W"
/db_xref="GeneID:850874"
mRNA 511054..512940
/locus_tag="YLR177W"
/product="hypothetical protein"
/transcript_id="NM_001182064.1"
/db_xref="GI:296146717"
/db_xref="GeneID:850874"
CDS 511054..512940
/locus_tag="YLR177W"
/note="hypothetical protein; phosphorylated by Dbf2p-Mob1p
in vitro; some strains contain microsatellite polymophisms
at this locus; YLR177W is not an essential gene"
/codon_start=1
/product="hypothetical protein"
/protein_id="NP_013278.1"
/db_xref="GI:6323206"
/db_xref="SGD:S000004167"
/db_xref="GeneID:850874"
/translation="MELPSINSTTSISDNQELRNYYDKLLFKNNSGKSLADLPGKMAD
FNDNSAAAHPRSRVDFINGYIGFREDKQSLLGQKNTKRASFSAFADEGRKQSEMSING
KSPNLSLFSFEFNGTPTQDRKPYKQDYLNVMNTSPNNILSPLNNSSQKYYPQKQQQQQ
QQQQQQQQQSIFDPGRRSSYISDALIHGNAATQQPQYSQPVYINNNPSLQVPYTAPSE
YTQQQQYSSPFNARRNTQPVLNLHPAAAPTNDAGLAVVDGKNLTSSKELHDLYLDCGS
NYFASDKVYKFIDSIKGTLRGDNVSASSSRIIEFLDFLKNCNLNYNPQSDAFISTAVS
NASSTGAAKSKNSTSMHLHYKPLVLVSLKNGKLELLSKPQTATLILKRGDLVIIDGDR
GKDLVLVVEPVVDINLALFINFLKKKIHFDSLITNSQQHFPNDQFIKTLVDTTNGKPV
AHELNPKLYDIIELTQLIIPSKQVLRFATPWESSTNLHNKFQDELKALHIAQLKLRSL
NNNNSGGGLNIKILNAEFQFDRKKLTFYYICQERNDFRDLIKELFKFYKTRIWLCAIP
NNLSIDSKFYDSNKFEWEMYQDMMSHYSMDNTGIVVAPELNRLKLDDFQIGVYMELVK
VLFG"
rep_origin 512867..513115
/note="ARS1217;
Autonomously Replicating Sequence"
/db_xref="SGD:S000118476"
gene complement(513162..513821)
/gene="TFS1"
/locus_tag="YLR178C"
/gene_synonym="DKA1"
/db_xref="GeneID:850875"
mRNA complement(513162..513821)
/gene="TFS1"
/locus_tag="YLR178C"
/gene_synonym="DKA1"
/product="Tfs1p"
/transcript_id="NM_001182065.1"
/db_xref="GI:296146718"
/db_xref="GeneID:850875"
CDS complement(513162..513821)
/gene="TFS1"
/locus_tag="YLR178C"
/gene_synonym="DKA1"
/note="Protein that interacts with and inhibits
carboxypeptidase Y and Ira2p;
phosphatidylethanolamine-binding protein (PEBP) family
member; targets to vacuolar membranes during stationary
phase; acetylated by NatB N-terminal acetyltransferase;
protein abundance increases in response to DNA replication
stress"
/codon_start=1
/product="Tfs1p"
/protein_id="NP_013279.1"
/db_xref="GI:6323207"
/db_xref="SGD:S000004168"
/db_xref="GeneID:850875"
/translation="MNQAIDFAQASIDSYKKHGILEDVIHDTSFQPSGILAVEYSSSA
PVAMGNTLPTEKARSKPQFQFTFNKQMQKSVPQANAYVPQDDDLFTLVMTDPDAPSKT
DHKWSEFCHLVECDLKLLNEATHETSGATEFFASEFNTKGSNTLIEYMGPAPPKGSGP
HRYVFLLYKQPKGVDSSKFSKIKDRPNWGYGTPATGVGKWAKENNLQLVASNFFYAET
K"
gene complement(514108..514713)
/locus_tag="YLR179C"
/db_xref="GeneID:850876"
mRNA complement(514108..514713)
/locus_tag="YLR179C"
/product="hypothetical protein"
/transcript_id="NM_001182066.1"
/db_xref="GI:296146719"
/db_xref="GeneID:850876"
CDS complement(514108..514713)
/locus_tag="YLR179C"
/note="hypothetical protein with similarity to Tfs1p;
transcription is activated by paralogous proteins Yrm1p
and Yrr1p along with proteins involved in multidrug
resistance; GFP-tagged protein localizes to the cytoplasm
and nucleus"
/codon_start=1
/product="hypothetical protein"
/protein_id="NP_013280.1"
/db_xref="GI:6323208"
/db_xref="SGD:S000004169"
/db_xref="GeneID:850876"
/translation="MSSAIVAKLNKEDIIKDTVKDLAFEILGELSVSYVDSDDIKLGN
PMPMEATQAAPTIKFTPFDKSQLSAEDKLALLMTDPDAPSRTEHKWSEVCHYIITDIP
VEYGPGGDIAISGKGVVRNNYIGPGPPKNSGYHRYVFFLCKQPKGADSSTFTKVENII
SWGYGTPGAGAYDYIKENNLQLVGANYYMVENTTVDFNYDM"
gene 515262..516410
/gene="SAM1"
/locus_tag="YLR180W"
/gene_synonym="ETH10"
/db_xref="GeneID:850877"
mRNA 515262..516410
/gene="SAM1"
/locus_tag="YLR180W"
/gene_synonym="ETH10"
/product="methionine adenosyltransferase SAM1"
/transcript_id="NM_001182067.1"
/db_xref="GI:296146720"
/db_xref="GeneID:850877"
CDS 515262..516410
/gene="SAM1"
/locus_tag="YLR180W"
/gene_synonym="ETH10"
/EC_number="2.5.1.6"
/note="S-adenosylmethionine synthetase; catalyzes transfer
of the adenosyl group of ATP to the sulfur atom of
methionine; SAM1 has a paralog, SAM2, that arose from the
whole genome duplication"
/codon_start=1
/product="methionine adenosyltransferase SAM1"
/protein_id="NP_013281.1"
/db_xref="GI:6323209"
/db_xref="SGD:S000004170"
/db_xref="GeneID:850877"
/translation="MAGTFLFTSESVGEGHPDKICDQVSDAILDACLAEDPHSKVACE
TAAKTGMIMVFGEITTKAQLDYQKIVRDTIKKIGYDDSAKGFDYKTCNVLVAIEQQSP
DIAQGVHEEKDLEDIGAGDQGIMFGYATDETPEGLPLTILLAHKLNMAMADARRDGSL
AWLRPDTKTQVTVEYKDDHGRWVPQRIDTVVVSAQHADEITTEDLRAQLKSEIIEKVI
PRDMLDENTKYFIQPSGRFVIGGPQGDAGLTGRKIIVDAYGGASSVGGGAFSGKDYSK
VDRSAAYAARWVAKSLVAAGLCKRVQVQFSYAIGIAEPLSLHVDTYGTATKSDEEIID
IISKNFDLRPGVLVKELDLARPIYLPTASYGHFTNQEYPWEKPKTLKF"
gene complement(516678..517670)
/gene="VTA1"
/locus_tag="YLR181C"
/db_xref="GeneID:850878"
mRNA complement(516678..517670)
/gene="VTA1"
/locus_tag="YLR181C"
/product="Vta1p"
/transcript_id="NM_001182068.1"
/db_xref="GI:296146721"
/db_xref="GeneID:850878"
CDS complement(516678..517670)
/gene="VTA1"
/locus_tag="YLR181C"
/note="Multivesicular body (MVB) protein involved in
endosomal protein sorting; regulates Vps4p activity by
promoting its oligomerization; has an N-terminal Vps60-
and Did2- binding domain, a linker region, and a
C-terminal Vps4p binding domain"
/codon_start=1
/product="Vta1p"
/protein_id="NP_013282.1"
/db_xref="GI:6323210"
/db_xref="SGD:S000004171"
/db_xref="GeneID:850878"
/translation="MASNAARVVATAKDFDKVGLGIIGYYLQLYAVELILSEEDRSQE
MTALATELLDTIEAFKKEIGGESEAEDSDKSLHVMNTLIHDQEKAKIYMLNFTMSLYN
EKLKQLKDGPWDVMLKRSLWCCIDLFSCILHLWKENISETSTNSLQKRIKYCKIYLSK
LAKGEIGSSDEKTLDYADFADDSEEIKDEDVDHQTSDLENNNNDKVEGLAPKDQTTSY
EPVDEVPEFIDDADSVNEEEQTVDKNEDAITKDEQQVVKKEVDLTRPSAPSEPAAAEH
KSYTKDELTKIMDRASKIEQIQKLAKYAISALNYEDLPTAKDELTKALDLLNSI"
gene 517940..520351
/gene="SWI6"
/locus_tag="YLR182W"
/gene_synonym="PSL8; SDS11"
/db_xref="GeneID:850879"
mRNA 517940..520351
/gene="SWI6"
/locus_tag="YLR182W"
/gene_synonym="PSL8; SDS11"
/product="Swi6p"
/transcript_id="NM_001182069.1"
/db_xref="GI:296146722"
/db_xref="GeneID:850879"
CDS 517940..520351
/gene="SWI6"
/locus_tag="YLR182W"
/gene_synonym="PSL8; SDS11"
/note="Transcription cofactor; forms complexes with Swi4p
and Mbp1p to regulate transcription at the G1/S
transition; involved in meiotic gene expression; also
binds Stb1p to regulate transcription at START; cell wall
stress induces phosphorylation by Mpk1p, which regulates
Swi6p localization; required for the unfolded protein
response, independently of its known transcriptional
coactivators"
/codon_start=1
/product="Swi6p"
/protein_id="NP_013283.1"
/db_xref="GI:6323211"
/db_xref="SGD:S000004172"
/db_xref="GeneID:850879"
/translation="MALEEVVRYLGPHNEIPLTLTRDSETGHFLLKHFLPILQQYHDT
GNINETNPDSFPTDEERNKLLAHYGIAVNTDDRGELWIELEKCLQLLNMLNLFGLFQD
AFEFEEPETDQDEEDPSHSKLPENKTKSENSKDNISSKRINNLQDMSLDSDAHRELGS
PLKKLKIDTSVIDAESDSTPNTARGKPNDDINKGPSGDNENNGTDDNDRTAGPIITFT
HDLTSDFLSSPLKIMKALPSPVVNDNEQKMKLEAFLQRLLFPEIQEMPTSLNNDSSNR
NSEGGSSNQQQQHVSFDSLLQEVNDAFPNTQLNLNIPVDEHGNTPLHWLTSIANLELV
KHLVKHGSNRLYGDNMGESCLVKAVKSVNNYDSGTFEALLDYLYPCLILEDSMNRTIL
HHIIITSGMTGCSAAAKYYLDILMGWIVKKQNRPIQSGTNEKESKPNDKNGERKDSIL
ENLDLKWIIANMLNAQDSNGDTCLNIAARLGNISIVDALLDYGADPFIANKSGLRPVD
FGAGTSKLQNTNGGDENSKMVSKGDYDGQKNGKAKKIRSQLLKNPPETTSLINDVQNL
LNSISKDYENETVQYNEKLEKLHKELNEQREELANSREQLANVKQLKDEYSLMQEQLT
NLKAGIEEEEESFREESKKLGIIADESSGIDWDSSEYDADEPFKVEFLSDFLEDKLQK
NYEGDISKLLEAESKEQIMEQIRNQLPAEKIQSMLPPTVLLKARINAYKRNDKHLTNV
LDTISTKQSELENKFRRVLSLCLKIDENKVDNMLDGLLQAISSEDPQDIDTDEMQDFL
KKHAS"
gene complement(520543..522012)
/gene="TOS4"
/locus_tag="YLR183C"
/db_xref="GeneID:850880"
mRNA complement(520543..522012)
/gene="TOS4"
/locus_tag="YLR183C"
/product="Tos4p"
/transcript_id="NM_001182070.1"
/db_xref="GI:296146723"
/db_xref="GeneID:850880"
CDS complement(520543..522012)
/gene="TOS4"
/locus_tag="YLR183C"
/note="Forkhead Associated domain containing protein;
putative transcription factor found associated with
chromatin; target of SBF transcription factor; expression
is periodic and peaks in G1; similar to PLM2; relative
distribution to the nucleus increases upon DNA replication
stress"
/codon_start=1
/product="Tos4p"
/protein_id="NP_013284.1"
/db_xref="GI:6323212"
/db_xref="SGD:S000004173"
/db_xref="GeneID:850880"
/translation="MSSQFPSSPYRTVDPYSPPNYKQQPNCPSSNYEKAGKTASESIG
NFGKGDYPTPFPSSSIGRVSSPVRSNKVDAIPSSPAFPGQLAETSPKFSSKLSSPSRH
TRVINAELDPSKISTITVGRNSSQCDVALCKNKFISRVHASITYLPQTNEVKIHCFSM
NGLIVTYRKQFDCYQLKDTMNNNNRAYRLVPRFSNEKCVKEIQDEGGFINFTLEEGDT
VYMTYYKGIMLDFRQVLLRISLKEKNSSSEPLRFEKKAEFESESETKHMGSIRKHPLI
FTDTSMDRPKKILKDSNKISIGSDSGVAERMLNHFLNSKSSPLSSVSSVDHEEQTLRQ
DSLSSDKNPMTMKKPKLNKRVLPSKPKKSVKENLDELSRRNIDVMHLQHILTNHLAFA
NVQQTPLFQLQQVNSQISELSRDELRSILSDAKCVGVIYRHGKDAAGKPLDEEYFYDL
ENDDDYERRNLVSSLKGGRTGLRSCRRTHKQYFWKKPAK"
gene 522663..523288
/gene="RPL37A"
/locus_tag="YLR185W"
/db_xref="GeneID:850882"
mRNA join(522663..522669,523029..523288)
/gene="RPL37A"
/locus_tag="YLR185W"
/product="ribosomal 60S subunit protein L37A"
/transcript_id="NM_001182072.1"
/db_xref="GI:296146724"
/db_xref="GeneID:850882"
CDS join(522663..522669,523029..523288)
/gene="RPL37A"
/locus_tag="YLR185W"
/note="Ribosomal 60S subunit protein L37A; homologous to
mammalian ribosomal protein L37, no bacterial homolog;
RPL37A has a paralog, RPL37B, that arose from the whole
genome duplication"
/codon_start=1
/product="ribosomal 60S subunit protein L37A"
/protein_id="NP_013286.1"
/db_xref="GI:6323214"
/db_xref="SGD:S000004175"
/db_xref="GeneID:850882"
/translation="MGKGTPSFGKRHNKSHTLCNRCGRRSFHVQKKTCSSCGYPAAKT
RSYNWGAKAKRRHTTGTGRMRYLKHVSRRFKNGFQTGSASKASA"
gene 523632..524390
/gene="EMG1"
/locus_tag="YLR186W"
/gene_synonym="NEP1"
/db_xref="GeneID:850883"
mRNA 523632..524390
/gene="EMG1"
/locus_tag="YLR186W"
/gene_synonym="NEP1"
/product="Emg1p"
/transcript_id="NM_001182073.1"
/db_xref="GI:296146725"
/db_xref="GeneID:850883"
CDS 523632..524390
/gene="EMG1"
/locus_tag="YLR186W"
/gene_synonym="NEP1"
/note="Methyltransferase for rRNA; catalyzes methylation
of the pseudouridine residue 1191 of 18S rRNA; member of
the SPOUT methyltransferase family; required for
maturation of 18S rRNA and for 40S ribosomal subunit
production independently of methyltransferase activity;
forms homodimers; human ortholog is mutated in
Bowen-Conradi syndrome, and the equivalent mutation in
yeast affects Emg1p dimerization and localization but not
its methyltransferase activity"
/codon_start=1
/product="Emg1p"
/protein_id="NP_013287.1"
/db_xref="GI:6323215"
/db_xref="SGD:S000004176"
/db_xref="GeneID:850883"
/translation="MVEDSRVRDALKGGDQKALPASLVPQAPPVLTSKDKITKRMIVV
LAMASLETHKISSNGPGGDKYVLLNCDDHQGLLKKMGRDISEARPDITHQCLLTLLDS
PINKAGKLQVYIQTSRGILIEVNPTVRIPRTFKRFSGLMVQLLHKLSIRSVNSEEKLL
KVIKNPITDHLPTKCRKVTLSFDAPVIRVQDYIEKLDDDESICVFVGAMARGKDNFAD
EYVDEKVGLSNYPLSASVACSKFCHGAEDAWNIL"
gene 524865..527945
/gene="SKG3"
/locus_tag="YLR187W"
/db_xref="GeneID:850884"
mRNA 524865..527945
/gene="SKG3"
/locus_tag="YLR187W"
/product="Skg3p"
/transcript_id="NM_001182074.1"
/db_xref="GI:296146726"
/db_xref="GeneID:850884"
CDS 524865..527945
/gene="SKG3"
/locus_tag="YLR187W"
/note="hypothetical protein; green fluorescent protein
(GFP)-fusion protein localizes to the cell periphery,
cytoplasm, bud, and bud neck; potential Cdc28p substrate;
similar to Caf120p and Skg4p; relocalizes from bud neck to
cytoplasm upon DNA replication stress"
/codon_start=1
/product="Skg3p"
/protein_id="NP_013288.1"
/db_xref="GI:6323216"
/db_xref="SGD:S000004177"
/db_xref="GeneID:850884"
/translation="MKRIFSGVKSPKLSAPPKVFKNDESPSTPSSPKFDQGLRSLSAS
ASRLFSNSISTPGSPTLDLPQEHSINGDISPELVPIVTLLSAQAHRRYHYGIFLILHD
LKTDGTPAARQWEECYGVLLGTQLALWDAKELSDSKNNKNTSTMKKAASRPSFINFTD
ASVRSLDANDQVIIASENEKTKKDLDNVLVVSTTLKNRYFLKFKNSKSFKTWNAAIRL
SLFEFTALQEAYTGSFLSSRGVKLGDIKVVMADTKFTYEDWVSVRFGTGMPWKRCYAV
ISPQSGKKKKNSKGSICFYENNKKTKKSNIMTTVVDARALYAVYPSSPILIDTSTIIK
LEGFVSFDKSEEPQETNLFIMPEKHQGVPGYDTIIRFLIPAMNAFYLYGRPKGLIANR
TDPDSLLFALPTLPHIYYLQVDDVLSLTKDKNYIHWSAADWRNNIVQVLQKKLSKGYK
GCGNKTVSVSSGMMKSPAISSAELFEGYDSLPERQMESPQKSKMKSPTLASTDDINSA
SASVNSHATSVKQTELFVTDNSSKINDSVSAQSSVTTNFKDTFTTPMTSGMLNHENSE
RSFGSGLKLKITDSNLENMEDVEAKSANEFSTTPEDKHIHLANAAELSALYDKYSTSP
FGKSEANSSPKPQKLEVKDRSKNENRSPYERYVGTSAESKTFEIGNVRESKSTINTSL
SSPLRVEDSRRSKNEDLGSLKEFEELSQKISNMGMANISSEALSDTAENSSFVTDLNL
NINNSSSVNLNEEQRVPDFGEENVFDPDYMEQNQMLETESRYTTDEFDFSDNQDAASS
NYSNGQTNRTVTETLSASDRNDKIPHSSLFTNLNQLTSNGGNYQDREDFSGDQINKPQ
QSQPLHVKGPQTSSFGYRNSSANSSQPQAPYPVGRPLGKIRTGPLTVQPMQQGGNSSM
YSFQSSQHRFHSSQQRQNQSLSFRNNTYGSGNNQNTFHPSPQLQQQPQNMRYLNNKLP
INDRSPIPQTQHHVPDGRPSLHINTTNRTNPLTAQSGFSQFMPPNSTSTNPYSS"
gene 528300..530387
/gene="MDL1"
/locus_tag="YLR188W"
/db_xref="GeneID:850885"
mRNA 528300..530387
/gene="MDL1"
/locus_tag="YLR188W"
/product="ATP-binding cassette permease MDL1"
/transcript_id="NM_001182075.1"
/db_xref="GI:296146727"
/db_xref="GeneID:850885"
CDS 528300..530387
/gene="MDL1"
/locus_tag="YLR188W"
/note="Mitochondrial inner membrane half-type ATP-binding
cassette (ABC) transporter, mediates export of peptides
generated upon proteolysis of mitochondrial proteins,
plays a role in the regulation of cellular resistance to
oxidative stress"
/codon_start=1
/product="ATP-binding cassette permease MDL1"
/protein_id="NP_013289.1"
/db_xref="GI:6323217"
/db_xref="SGD:S000004178"
/db_xref="GeneID:850885"
/translation="MIVRMIRLCKGPKLLRSQFASASALYSTKSLFKPPMYQKAEINL
IIPHRKHFLLRSIRLQSDIAQGKKSTKPTLKLSNANSKSSGFKDIKRLFVLSKPESKY
IGLALLLILISSSVSMAVPSVIGKLLDLASESDGEDEEGSKSNKLYGFTKKQFFTALG
AVFIIGAVANASRIIILKVTGERLVARLRTRTMKAALDQDATFLDTNRVGDLISRLSS
DASIVAKSVTQNVSDGTRAIIQGFVGFGMMSFLSWKLTCVMMILAPPLGAMALIYGRK
IRNLSRQLQTSVGGLTKVAEEQLNATRTIQAYGGEKNEVRRYAKEVRNVFHIGLKEAV
TSGLFFGSTGLVGNTAMLSLLLVGTSMIQSGSMTVGELSSFMMYAVYTGSSLFGLSSF
YSELMKGAGAAARVFELNDRKPLIRPTIGKDPVSLAQKPIVFKNVSFTYPTRPKHQIF
KDLNITIKPGEHVCAVGPSGSGKSTIASLLLRYYDVNSGSIEFGDEDIRNFNLRKYRR
LIGYVQQEPLLFNGTILDNILYCIPPEIAEQDDRIRRAIGKANCTKFLANFPDGLQTM
VGARGAQLSGGQKQRIALARAFLLDPAVLILDEATSALDSQSEEIVAKNLQRRVERGF
TTISIAHRLSTIKHSTRVIVLGKHGSVVETGSFRDLIAIPNSELNALLAEQQDEEGKG
GVIDLDNSVAREV"
gene complement(530797..534393)
/gene="ATG26"
/locus_tag="YLR189C"
/gene_synonym="UGT51"
/db_xref="GeneID:850886"
mRNA complement(530797..534393)
/gene="ATG26"
/locus_tag="YLR189C"
/gene_synonym="UGT51"
/product="Atg26p"
/transcript_id="NM_001182076.1"
/db_xref="GI:296146728"
/db_xref="GeneID:850886"
CDS complement(530797..534393)
/gene="ATG26"
/locus_tag="YLR189C"
/gene_synonym="UGT51"
/EC_number="2.4.1.173"
/note="UDP-glucose:sterol glucosyltransferase, conserved
enzyme involved in synthesis of sterol glucoside membrane
lipids; in contrast to ATG26 from P. pastoris, S.
cerevisiae ATG26 is not involved in autophagy"
/codon_start=1
/product="Atg26p"
/protein_id="NP_013290.1"
/db_xref="GI:6323218"
/db_xref="SGD:S000004179"
/db_xref="GeneID:850886"
/translation="MPITQIISASDSEAGPKPSISLVPDKPSEPETSPRHHRLSRSLS
KFKRWRGRSNSSLSMGSSEQQELQDSPNEARSDDDENGYNNDNADDLAKSKYMMKSIA
GLLTTASVYAGMNNAQEMNVLSQVDSEESDSSDSFQENIGRNEVKSKKENLKTKSHPE
VPRLDKRKPTLFDFSITREKLSKDNVAKLRQRFCLDEQEPFLNDFPAWLLKDVLVQGH
IFITTKHFLFFAYLPKNPRSVKMSGNLNIRTKLIRSTRYWCVLKNHLFSMYTSSTELY
FPVLTIDLREVQKIETQKHTLNGSATKTFKLYTDESTFKFNADSEFSAKSWVNALKKE
QFAAQNSENNSISLKIPLPNIIEIDDQPIVNKALTLRLRALESSQTYAIDDFMFVFMD
GSGSQVKESLGEQLAILQKSGVNTLYYDIPAKKSKSSFGKETPATVEQKNNGEDSKYL
NVPTSAVPSSENGKKSRFRFRERSNSWFRRAKPLEDSQVEDVEEIYKDAANDIDSSVH
STIHIHEQEDSQEQTVAWKPSHLKNFAEMWAAKPIHYRNKFIPFQKDDTYLIKETEEV
SANERFRYHFKFNKEKSLISTYYTYLNRNVPVYGKIYVSNDTVCFRSLLPGSNTYMVL
PLVDVETCYKEKGFRFGYFVLVIVIHGHEELFFEFSTEVARDDIERILLKLLDNIYAS
SAEGSNISSASLGDVQHNPDSAKLKLFEDKINAEGFEVPLMIDENPHYKTSIKPNKSY
KFGLLTIGSRGDVQPYIALGKGLIKEGHQVVIITHSEFRDFVESHGIQFEEIAGNPVE
LMSLMVENESMNVKMLREASSKFRGWIDALLQTSWEVCNRRKFDILIESPSAMVGIHI
TEALQIPYFRAFTMPWTRTRAYPHAFIVPDQKRGGNYNYLTHVLFENVFWKGISGQVN
KWRVETLGLGKTNLFLLQQNNVPFLYNVSPTIFPPSIDFSEWVRVTGYWFLDDKSTFK
PPAELQEFISEARSKGKKLVYIGFGSIVVSNAKEMTEALVEAVMEADVYCILNKGWSE
RLGDKAAKKTEVDLPRNILNIGNVPHDWLFPQVDAAVHHGGSGTTGASLRAGLPTVIK
PFFGDQFFYAGRVEDIGVGIALKKLNAQTLADALKVATTNKIMKDRAGLIKKKISKED
GIKTAISAIYNELEYARSVTLSRVKTPRKKEENVDATKLTPAETTDEGWTMI"
gene 535214..536689
/gene="MMR1"
/locus_tag="YLR190W"
/db_xref="GeneID:850887"
mRNA 535214..536689
/gene="MMR1"
/locus_tag="YLR190W"
/product="Mmr1p"
/transcript_id="NM_001182077.1"
/db_xref="GI:296146729"
/db_xref="GeneID:850887"
CDS 535214..536689
/gene="MMR1"
/locus_tag="YLR190W"
/note="Phosphorylated protein of the mitochondrial outer
membrane, localizes only to mitochondria of the bud;
interacts with Myo2p to mediate mitochondrial distribution
to buds; mRNA is targeted to the bud via the transport
system involving She2p"
/codon_start=1
/product="Mmr1p"
/protein_id="NP_013291.1"
/db_xref="GI:6323219"
/db_xref="SGD:S000004180"
/db_xref="GeneID:850887"
/translation="MNSPTMKSEQLTPKLSPMSFCLDDQRNAGSFQNLLNSPTKLKLD
TGPIGNSLLYPTSLSKLSELSRGGRSKQRRGSDTMRSVSPIRFQFLNNTPKMLKPEYL
SQTTSNLPLLSALLKNSKKTTSEGQNSNPDPLNIEKNIIKQSIKDKLEQLRSSESVAQ
VQKKERNPPSFEAKVCAEEPILRKNAEGLLPSYVPVPATPLEDPENHGVRKVEDKGLR
VVSGGSTQCLSTEVNELPKDLNLDNLPTDNNGFVQYGLKGNNNNNRYSFISSTSTDYE
PEWCDGQQHISMQMASMANAEEANSREKSNLDIKIKQLELEITELKLQNEKLVHSMTT
NRYIEERFMLEVMKDPSIQAQRSQRDIERKVKQLEKKFFNCKKVLKKLTESSAVVATS
TSKTEGNSARIPCPKTRLARVSVLDLKKIEEQPDSSSGTSSEEDHLTNDDTDANTSED
LNVAFEEEPTSAISTTASVQSGESKRGFQLNLPVQVEKKEK"
gene 537272..538432
/gene="PEX13"
/locus_tag="YLR191W"
/gene_synonym="PAS20"
/db_xref="GeneID:850888"
mRNA 537272..538432
/gene="PEX13"
/locus_tag="YLR191W"
/gene_synonym="PAS20"
/product="Pex13p"
/transcript_id="NM_001182078.1"
/db_xref="GI:296146730"
/db_xref="GeneID:850888"
CDS 537272..538432
/gene="PEX13"
/locus_tag="YLR191W"
/gene_synonym="PAS20"
/note="Integral peroxisomal membrane protein required for
translocation of peroxisomal matrix proteins, interacts
with the PTS1 signal recognition factor Pex5p and the PTS2
signal recognition factor Pex7p, forms a complex with
Pex14p and Pex17p"
/codon_start=1
/product="Pex13p"
/protein_id="NP_013292.1"
/db_xref="GI:6323220"
/db_xref="SGD:S000004181"
/db_xref="GeneID:850888"
/translation="MSSTAVPRPKPWETSASLEEPQRNAQSLSAMMTSNQQDSRPTEE
SNNSNSASESAPEVLPRPAALNSSGTYGESNTIPGIYGNSNYGIPYDNNPYSMNSIYG
NSIGRYGYGGSYYGNNYGSFYGGGYGAGAGYGMNNGSGLGESTKATFQLIESLIGAVT
GFAQMLESTYMATHNSFFTMISVAEQFGNLKEMLGSFFGIFAIMKFLKKILYRATKGR
LGIPPKNFAESEGSKNKLIEDFQKFNDSGTINSNEKATRRKISWKPLLFFLMAVFGFP
YLLNKFITKLQTSGTIRASQGNGSEPIDPSKLEFARALYDFVPENPEMEVALKKGDLM
AILSKKDPLGRDSDWWKVRTKNGNIGYIPYNYIEIIKRRKKIEHVDDETRTH"
gene complement(538792..539589)
/gene="HCR1"
/locus_tag="YLR192C"
/db_xref="GeneID:850889"
mRNA complement(538792..539589)
/gene="HCR1"
/locus_tag="YLR192C"
/product="Hcr1p"
/transcript_id="NM_001182079.1"
/db_xref="GI:296146731"
/db_xref="GeneID:850889"
CDS complement(538792..539589)
/gene="HCR1"
/locus_tag="YLR192C"
/note="Dual function protein involved in translation
initiation as a substoichiometric component (eIF3j) of
translation initiation factor 3 (eIF3) and required for
processing of 20S pre-rRNA; binds to eIF3 subunits Rpg1p
and Prt1p and 18S rRNA"
/codon_start=1
/product="Hcr1p"
/protein_id="NP_013293.1"
/db_xref="GI:6323221"
/db_xref="SGD:S000004182"
/db_xref="GeneID:850889"
/translation="MSWDDEAINGSMGNDDAVLMDSWDAEIGDDEPVMQSWDAEEEEK
KPAPKPKKEQPKKVKKGKESSADRALLDIDTLDEKTRKELIKKAEMESDLNNAADLFA
GLGVAEEHPRARALQKEQEEQALKRPAFTKDTPIETHPLFNAETKREYQDLRKALTAA
ITPMNKKSPLNYSSSLAIDLIRDVAKPMSIESIRQTVATLNVLIKDKEREERQARLAR
VRGGTATGGAGKKKVKGKTNLGGAFKKDQDFDLDGPDDFEFGDDDFM"
gene complement(540009..540536)
/gene="UPS1"
/locus_tag="YLR193C"
/db_xref="GeneID:850890"
mRNA complement(540009..540536)
/gene="UPS1"
/locus_tag="YLR193C"
/product="Ups1p"
/transcript_id="NM_001182080.1"
/db_xref="GI:296146732"
/db_xref="GeneID:850890"
CDS complement(540009..540536)
/gene="UPS1"
/locus_tag="YLR193C"
/note="Mitochondrial protein involved in phospholipid
metabolism; localizes to the intermembrane space; has a
role in regulation of phospholipid metabolism by promoting
conversion of phosphatidylethanolamine to
phosphatidylcholine; null mutant has altered cardiolipin
and phosphatidylethanolamine levels and defects in Mgm1p
processing, integrity of mitochondrial inner membrane
complexes, and mitochondrial morphology; ortholog of human
PRELI"
/codon_start=1
/product="Ups1p"
/protein_id="NP_013294.1"
/db_xref="GI:6323222"
/db_xref="SGD:S000004183"
/db_xref="GeneID:850890"
/translation="MVLLHKSTHIFPTDFASVSRAFFNRYPNPYSPHVLSIDTISRNV
DQEGNLRTTRLLKKSGKLPTWVKPFLRGITETWIIEVSVVNPANSTMKTYTRNLDHTG
IMKVEEYTTYQFDSATSSTIADSRVKFSSGFNMGIKSKVEDWSRTKFDENVKKSRMGM
AFVIQKLEEARNPQF"
gene complement(540809..541573)
/locus_tag="YLR194C"
/db_xref="GeneID:850891"
mRNA complement(540809..541573)
/locus_tag="YLR194C"
/product="hypothetical protein"
/transcript_id="NM_001182081.1"
/db_xref="GI:296146733"
/db_xref="GeneID:850891"
CDS complement(540809..541573)
/locus_tag="YLR194C"
/note="Structural constituent of the cell wall attached to
the plasma membrane by a GPI-anchor; expression is
upregulated in response to cell wall stress"
/codon_start=1
/product="hypothetical protein"
/protein_id="NP_013295.1"
/db_xref="GI:6323223"
/db_xref="SGD:S000004184"
/db_xref="GeneID:850891"
/translation="MKACSILFTTLITLAAAQKDSGSLDGQNSEDSSQKESSNSQEIT
PTTTKEAQESASTVVSTGKSLVQTSNVVSNTYAVAPSTTVVTTDAQGKTTTQYLWWVA
ESNSAVSTTSTASVQPTGETSSGITNSASSSTTSTSTDGPVTIVTTTNSLGETYTSTV
WWLPSSATTDNTASSSKSSSGSSSKPESSTKVVSTIKSTYTTTSGSTVETLTTTYKST
VNGKVASVMSNSTNGAFAGTHIAYGAGAFAVGALLL"
gene complement(541937..543304)
/gene="NMT1"
/locus_tag="YLR195C"
/gene_synonym="CDC72"
/db_xref="GeneID:850892"
mRNA complement(541937..543304)
/gene="NMT1"
/locus_tag="YLR195C"
/gene_synonym="CDC72"
/product="Nmt1p"
/transcript_id="NM_001182082.1"
/db_xref="GI:296146734"
/db_xref="GeneID:850892"
CDS complement(541937..543304)
/gene="NMT1"
/locus_tag="YLR195C"
/gene_synonym="CDC72"
/EC_number="2.3.1.97"
/note="N-myristoyl transferase, catalyzes the
cotranslational, covalent attachment of myristic acid to
the N-terminal glycine residue of several proteins
involved in cellular growth and signal transduction"
/codon_start=1
/product="Nmt1p"
/protein_id="NP_013296.1"
/db_xref="GI:6323224"
/db_xref="SGD:S000004185"
/db_xref="GeneID:850892"
/translation="MSEEDKAKKLENLLKLLQLNNDDTSKFTQEQKKAMKDHKFWRTQ
PVKDFDEKVVEEGPIDKPKTPEDISDKPLPLLSSFEWCSIDVDNKKQLEDVFVLLNEN
YVEDRDAGFRFNYTKEFFNWALKSPGWKKDWHIGVRVKETQKLVAFISAIPVTLGVRG
KQVPSVEINFLCVHKQLRSKRLTPVLIKEITRRVNKCDIWHALYTAGIVLPAPVSTCR
YTHRPLNWKKLYEVDFTGLPDGHTEEDMIAENALPAKTKTAGLRKLKKEDIDQVFELF
KRYQSRFELIQIFTKEEFEHNFIGEESLPLDKQVIFSYVVEQPDGKITDFFSFYSLPF
TILNNTKYKDLGIGYLYYYATDADFQFKDRFDPKATKALKTRLCELIYDACILAKNAN
MDVFNALTSQDNTLFLDDLKFGPGDGFLNFYLFNYRAKPITGGLNPDNSNDIKRRSNV
GVVML"
gene 543968..545698
/gene="PWP1"
/locus_tag="YLR196W"
/db_xref="GeneID:850893"
mRNA 543968..545698
/gene="PWP1"
/locus_tag="YLR196W"
/product="Pwp1p"
/transcript_id="NM_001182083.1"
/db_xref="GI:296146735"
/db_xref="GeneID:850893"
CDS 543968..545698
/gene="PWP1"
/locus_tag="YLR196W"
/note="Protein with WD-40 repeats involved in rRNA
processing; associates with trans-acting ribosome
biogenesis factors; similar to beta-transducin
superfamily"
/codon_start=1
/product="Pwp1p"
/protein_id="NP_013297.1"
/db_xref="GI:6323225"
/db_xref="SGD:S000004186"
/db_xref="GeneID:850893"
/translation="MISATNWVPRGFSSEFPEKYVLDDEEVERINQLAQLNLDDAKAT
LEEAEGESGVEDDAATGSSNKLKDQLDIDDDLKEYNLEEYDDEEIADNEGGKDVSMFP
GLSNDSDVKFHEGEKGEDPYISLPNQEDSQEEKQELQVYPSDNLVLAARTEDDVSYLD
IYVYDDGAGFHSSDIPVEEGDEADPDVARGLVRDPALYVHHDLMLPAFPLCVEWLDYK
VGSNSEEAANYAAIGTFDPQIEIWNLDCVDKAFPDMILGEPLDNSMVSLKSKKKKKKS
KTGHITTHHTDAVLSMAHNKYFRSVLASTSADHTVKLWDLNSGNAARSLASIHSNKNV
SSSEWHMLNGSILLTGGYDSRVALTDVRISDESQMSKYWSAMAGEEIETVTFASENII
LCGTDSGNVYSFDIRNNENRKPVWTLKAHDAGISTLCSNKFIPGMMSTGAMGEKTVKL
WKFPLDDATNTKGPSMVLSRDFDVGNVLTSSFAPDIEVAGTMVIGGVNKVLKLWDVFT
NRSVRKSFKSELENVQARAKEEAQKIGKSSRIARKYTSNDNPDTVITIDDQGEDEEER
EGGDEHDDMA"
gene 546097..547611
/gene="NOP56"
/locus_tag="YLR197W"
/gene_synonym="SIK1"
/db_xref="GeneID:850894"
mRNA 546097..547611
/gene="NOP56"
/locus_tag="YLR197W"
/gene_synonym="SIK1"
/product="Nop56p"
/transcript_id="NM_001182084.1"
/db_xref="GI:296146736"
/db_xref="GeneID:850894"
CDS 546097..547611
/gene="NOP56"
/locus_tag="YLR197W"
/gene_synonym="SIK1"
/note="Essential evolutionarily-conserved nucleolar
protein component of the box C/D snoRNP complexes that
direct 2'-O-methylation of pre-rRNA during its maturation;
overexpression causes spindle orientation defects"
/codon_start=1
/product="Nop56p"
/protein_id="NP_013298.1"
/db_xref="GI:6323226"
/db_xref="SGD:S000004187"
/db_xref="GeneID:850894"
/translation="MAPIEYLLFEEPTGYAVFKVKLQQDDIGSRLKEVQEQINDFGAF
TKLIELVSFAPFKGAAEALENANDISEGLVSESLKAILDLNLPKASSKKKNITLAISD
KNLGPSIKEEFPYVDCISNELAQDLIRGVRLHGEKLFKGLQSGDLERAQLGLGHAYSR
AKVKFSVQKNDNHIIQAIALLDQLDKDINTFAMRVKEWYGWHFPELAKLVPDNYTFAK
LVLFIKDKASLNDDSLHDLAALLNEDSGIAQRVIDNARISMGQDISETDMENVCVFAQ
RVASLADYRRQLYDYLCEKMHTVAPNLSELIGEVIGARLISHAGSLTNLSKQAASTVQ
ILGAEKALFRALKTKGNTPKYGLIYHSGFISKASAKNKGRISRYLANKCSMASRIDNY
SEEPSNVFGSVLKKQVEQRLEFYNTGKPTLKNELAIQEAMELYNKDKPAAEVEETKEK
ESSKKRKLEDDDEEKKEKKEKKSKKEKKEKKEKKDKKEKKDKKEKKDKKKKSKD"
gene complement(547853..548769)
/gene="PBA1"
/locus_tag="YLR199C"
/gene_synonym="POC1"
/db_xref="GeneID:850896"
mRNA complement(join(547853..548677,548764..548769))
/gene="PBA1"
/locus_tag="YLR199C"
/gene_synonym="POC1"
/product="Pba1p"
/transcript_id="NM_001182086.1"
/db_xref="GI:296146737"
/db_xref="GeneID:850896"
CDS complement(join(547853..548677,548764..548769))
/gene="PBA1"
/locus_tag="YLR199C"
/gene_synonym="POC1"
/note="Protein involved in 20S proteasome assembly; forms
a heterodimer with Add66p that binds to proteasome
precursors; similar to human PAC1 constituent of the
PAC1-PAC2 complex involved in proteasome assembly"
/codon_start=1
/product="Pba1p"
/protein_id="NP_013300.2"
/db_xref="GI:37362679"
/db_xref="SGD:S000004189"
/db_xref="GeneID:850896"
/translation="MLFKQWNDLPEPKHLLDLPEISKNLQSLEVCPVPKVEFPQDLDV
PQYSTAVITTKIMNPLFPKNLLQLTSIGEIKTTLTVKSPSLPQSSGKHSWNYDENFPN
EVDPDQKNDTADETVYGFSFPIYSFGKTLLFSMEENFISISPIFGNMISRSIISQLAQ
FSPDIIVIGTSDKIASMKVMTENECTLQPPEFITGFIGSVLTQLIVGPSKGLKFKCLV
APSEGPNGFEKLSLSDMGSLVDLCGQWLGFEPSRYSEECYRLWRCDSAAIGAQSGLYI
"
gene 549012..549356
/gene="YKE2"
/locus_tag="YLR200W"
/gene_synonym="GIM1; PFD6"
/db_xref="GeneID:850897"
mRNA 549012..549356
/gene="YKE2"
/locus_tag="YLR200W"
/gene_synonym="GIM1; PFD6"
/product="Yke2p"
/transcript_id="NM_001182087.1"
/db_xref="GI:296146738"
/db_xref="GeneID:850897"
CDS 549012..549356
/gene="YKE2"
/locus_tag="YLR200W"
/gene_synonym="GIM1; PFD6"
/note="Subunit of the heterohexameric Gim/prefoldin
protein complex involved in the folding of alpha-tubulin,
beta-tubulin, and actin"
/codon_start=1
/product="Yke2p"
/protein_id="NP_013301.1"
/db_xref="GI:6323229"
/db_xref="SGD:S000004190"
/db_xref="GeneID:850897"
/translation="MSELGAKYQQLQNELEEFIVARQKLETQLQENKIVNEEFDQLEE
DTPVYKLTGNVLLPVEQSEARTNVDKRLEFIETEITRCEKNIRDKQEELEKMRSELIK
LNNTAASTGPGR"
gene complement(549511..550293)
/gene="COQ9"
/locus_tag="YLR201C"
/db_xref="GeneID:850898"
mRNA complement(549511..550293)
/gene="COQ9"
/locus_tag="YLR201C"
/product="Coq9p"
/transcript_id="NM_001182088.1"
/db_xref="GI:296146739"
/db_xref="GeneID:850898"
CDS complement(549511..550293)
/gene="COQ9"
/locus_tag="YLR201C"
/note="Protein required for ubiquinone (coenzyme Q)
biosynthesis and respiratory growth; localizes to the
matrix face of the mitochondrial inner membrane in a large
complex with ubiquinone biosynthetic enzymes"
/codon_start=1
/product="Coq9p"
/protein_id="NP_013302.1"
/db_xref="GI:6323230"
/db_xref="SGD:S000004191"
/db_xref="GeneID:850898"
/translation="MLCRNTARTGCKFFRLYHSNPIEHVKPIHIKPLTYGKESPQYKV
LSLALQKFVPEHGFSERSIVESLNELGYPSSMISSIGAPNSPSFFHSSTAVMELIKFQ
LVDKRYRLTEGINPDVTPQYKLPSLEHLLLKRLEMDKPIGGHLSELMSQLAIPSAFLF
ETAIPELHRLSDDMIYFSNEKDHHDSAWYAKRLAVSSTYIGSKLFMAQDKSHNYKETF
TFAKDKLHRVMRLGEYYNNTEEFAWYTLMSTVNLIKSQLVRG"
gene complement(550650..551960)
/gene="MSS51"
/locus_tag="YLR203C"
/db_xref="GeneID:850900"
mRNA complement(550650..551960)
/gene="MSS51"
/locus_tag="YLR203C"
/product="Mss51p"
/transcript_id="NM_001182090.1"
/db_xref="GI:296146740"
/db_xref="GeneID:850900"
CDS complement(550650..551960)
/gene="MSS51"
/locus_tag="YLR203C"
/note="Specific translational activator for the
mitochondrial COX1 mRNA; loosely associated with the
matrix face of the mitochondrial inner membrane;
influences both COX1 mRNA translation and Cox1p assembly
into cytochrome c oxidase"
/codon_start=1
/product="Mss51p"
/protein_id="NP_013304.1"
/db_xref="GI:6323232"
/db_xref="SGD:S000004193"
/db_xref="GeneID:850900"
/translation="MTVLYAPSGATQLYFHLLRKSPHNRLVVSHQTRRHLMGFVRNAL
GLDPPPSPEDPTPENRFHPWDQSPSVDLRERAAKIRTLAHCPVTGKDINYTCPLSGIP
THHSREAWEMDKAYHDSKKYEILKKVNIYEHDLRSGRPFPEFDFPQQQGYDKAVNLTN
WDLFFYTRSFYSMDTEFQLAAVTKMLSYPITIGSLLHKFSPYSLNPKGPITLEGLKSL
AALRYTLYPLENRSLPTTTKNRAMRIFILGARAEAQLPGHVWKQLQFLFPEQSFEIHF
IGPECLYKRDKQEYVKSTTPVVQRVDETLKFIYRTNFFEVFHEAQDFFPYDPYMDVFF
TFHPGYASPESHGSWMGETMKALLETKCAIFTTGFNKKDLTDDINLVKSKYGKEMDVL
MEPVRNVFGSTKWELNDMNPQEVYQFNMYIAGFRGKRYHTIKRQ"
gene 552270..552605
/gene="QRI5"
/locus_tag="YLR204W"
/gene_synonym="COX24"
/db_xref="GeneID:850901"
mRNA 552270..552605
/gene="QRI5"
/locus_tag="YLR204W"
/gene_synonym="COX24"
/product="Qri5p"
/transcript_id="NM_001182091.1"
/db_xref="GI:296146741"
/db_xref="GeneID:850901"
CDS 552270..552605
/gene="QRI5"
/locus_tag="YLR204W"
/gene_synonym="COX24"
/note="Mitochondrial inner membrane protein, required for
accumulation of spliced COX1 mRNA; may have an additional
role in translation of COX1 mRNA"
/codon_start=1
/product="Qri5p"
/protein_id="NP_013305.1"
/db_xref="GI:6323233"
/db_xref="SGD:S000004194"
/db_xref="GeneID:850901"
/translation="MLGRALRPGWLGITRTVVKKPSCGSYFNRTFQTAINTTMPPMQE
GMLSTMMMMTATATRITGTVSEPLNGSNIVMQLDSVMRKRKKKMKKHKLRKRRKREKA
ERRKLSQGR"
gene complement(552724..553677)
/gene="HMX1"
/locus_tag="YLR205C"
/db_xref="GeneID:850902"
mRNA complement(552724..553677)
/gene="HMX1"
/locus_tag="YLR205C"
/product="Hmx1p"
/transcript_id="NM_001182092.1"
/db_xref="GI:296146742"
/db_xref="GeneID:850902"
CDS complement(552724..553677)
/gene="HMX1"
/locus_tag="YLR205C"
/note="ER localized heme oxygenase, involved in heme
degradation during iron starvation and in the oxidative
stress response; expression is regulated by AFT1 and
oxidative stress; relocates to the perinuclear region in
the presence of oxidants"
/codon_start=1
/product="Hmx1p"
/protein_id="NP_013306.2"
/db_xref="GI:42742287"
/db_xref="SGD:S000004195"
/db_xref="GeneID:850902"
/translation="MEDSSNTIIPSPTDVGALANRINFQTRDAHNKINTFMGIKMAIA
MRHGFIYRQGILAYYYVFDAIEQEIDRLLNDPVTEEELQTSTILKQFWLEDFRRSTQI
YKDLKLLYSNTFKSTESLNEFLATFQKPPLLQQFINNIHENIHKEPCTILSYCHVLYL
ALFAGGKLIRSNLYRRLGLFPNFEKLSQKELVKKGTNFFTFSDLGPTEETRLKWEYKK
NYELATRTELTEAQKLQIISVAEGIFDWNFNIVAEIGELNRRELMGKFSFKCITYLYE
EWMFNKDSATRRALHTVMLLVLSIIAIWVLYFLVKSFLSIV"
gene 554578..556419
/gene="ENT2"
/locus_tag="YLR206W"
/db_xref="GeneID:850903"
mRNA 554578..556419
/gene="ENT2"
/locus_tag="YLR206W"
/product="Ent2p"
/transcript_id="NM_001182093.1"
/db_xref="GI:296146743"
/db_xref="GeneID:850903"
CDS 554578..556419
/gene="ENT2"
/locus_tag="YLR206W"
/note="Epsin-like protein required for endocytosis and
actin patch assembly and functionally redundant with
Ent1p; contains clathrin-binding motif at C-terminus"
/codon_start=1
/product="Ent2p"
/protein_id="NP_013307.1"
/db_xref="GI:6323235"
/db_xref="SGD:S000004196"
/db_xref="GeneID:850903"
/translation="MSKQFVRSAKNMMKGYSSTQVLVRDATANDSRTPSIDTLDDLAQ
RSYDSVDFFEIMDMLDKRLNDKGKYWRHVAKSLTVLDYLVRFGSENCVLWCRENFYVI
KTLREFRHENESGFDEGQIIRVKAKELVSLLNDEERLREERSMNTRNRRANRAARPRP
RRQRTRSNPHDSSPSYQDDLEKALEESRITAQEDEQRRRELAQYDDEDPDFQAALQLS
KEEEELKQLQELQRLQKQQQSLSQFQAPLQQQQPQQQPAYYDIFGNPISQDEYLQYQY
QQDQEQAMAQQRWLDQQQEQQQLAEQQYFQQQQQAAAAASALQQQQTAANMQQQQQQP
ADFQQPLPTGSNNPFSMDNLERQKQEQQHAQLQRQQEEARQQQEQLKLQQLQRQQQEE
AQLHQKRQEEAQLQQQQAQLLQQQAQFQQQQPLKQTRTGNQSISDKYSDLNTLLATGT
GIDTFGNTGEARIPAQHTKTGTFINSQGTGYKQVTNEPKNNPFLSNQYTGLPSTNIVP
TQTGYGFGNQPQSPPTNSPQQNPTGISYSQPQQQQQPQQQPQYMQNFQQQQPQYAQNF
QQQPQYTQNYQQQPQYIQPHQQQQQQQQQQQQQQGYTPDQGVSLIDL"
gene 556788..559289
/gene="HRD3"
/locus_tag="YLR207W"
/db_xref="GeneID:850904"
mRNA 556788..559289
/gene="HRD3"
/locus_tag="YLR207W"
/product="ubiquitin ligase complex subunit HRD3"
/transcript_id="NM_001182094.1"
/db_xref="GI:296146744"
/db_xref="GeneID:850904"
CDS 556788..559289
/gene="HRD3"
/locus_tag="YLR207W"
/note="Resident protein of the ER membrane that plays a
central role in ER-associated protein degradation (ERAD),
forms HRD complex with Hrd1p and ERAD determinants that
engages in lumen to cytosol communication and coordination
of ERAD events"
/codon_start=1
/product="ubiquitin ligase complex subunit HRD3"
/protein_id="NP_013308.1"
/db_xref="GI:6323236"
/db_xref="SGD:S000004197"
/db_xref="GeneID:850904"
/translation="MITLLLYLCVICNAIVLIRADSIADPWPEARHLLNTIAKSRDPM
KEAAMEPNADEFVGFYVPMDYSPRNEEKNYQSIWQNEITDSQRHIYELLVQSSEQFNN
SEATYTLSQIHLWSQYNFPHNMTLAHKYLEKFNDLTHFTNHSAIFDLAVMYATGGCAS
GNDQTVIPQDSAKALLYYQRAAQLGNLKAKQVLAYKYYSGFNVPRNFHKSLVLYRDIA
EQLRKSYSRDEWDIVFPYWESYNVRISDFESGLLGKGLNSVPSSTVRKRTTRPDIGSP
FIAQVNGVQMTLQIEPMGRFAFNGNDGNINGDEDDEDASERRIIRIYYAALNDYKGTY
SQSRNCERAKNLLELTYKEFQPHVDNLDPLQVFYYVRCLQLLGHMYFTGEGSSKPNIH
MAEEILTTSLEISRRAQGPIGRACIDLGLINQYITNNISQAISYYMKAMKTQANNGIV
EFQLSKLATSFPEEKIGDPFNLMETAYLNGFIPAIYEFAVMIESGMNSKSSVENTAYL
FKTFVDKNEAIMAPKLRTAFAALINDRSEVALWAYSQLAEQGYETAQVSAAYLMYQLP
YEFEDPPRTTDQRKTLAISYYTRAFKQGNIDAGVVAGDIYFQMQNYSKAMALYQGAAL
KYSIQAIWNLGYMHEHGLGVNRDFHLAKRYYDQVSEHDHRFYLASKLSVLKLHLKSWL
TWITREKVNYWKPSSPLNPNEDTQHSKTSWYKQLTKILQRMRHKEDSDKAAEDSHKHR
TVVQNGANHRGDDQEEASEILGFQMEDLVTMGCILGIFLLSILMSTLAARRGWNVRFN
GAQLNANGNRQQEQQQQQQAQGPPGWDFNVQIFAI"
gene 559551..560444
/gene="SEC13"
/locus_tag="YLR208W"
/gene_synonym="ANU3"
/db_xref="GeneID:850905"
mRNA 559551..560444
/gene="SEC13"
/locus_tag="YLR208W"
/gene_synonym="ANU3"
/product="Sec13p"
/transcript_id="NM_001182095.1"
/db_xref="GI:296146745"
/db_xref="GeneID:850905"
CDS 559551..560444
/gene="SEC13"
/locus_tag="YLR208W"
/gene_synonym="ANU3"
/note="Structural component of 3 distinct complexes;
subunit of Nup84 nuclear pore sub-complex (NPC), COPII
vesicle coat, and Seh1-associated (SEA) complex; COPII
vesicle coat is required for ER to Golgi transport; the
Nup84 subcomplex contributes to nucleocytoplasmic
transport, NPC biogenesis and processes that may require
localization of chromosomes at the nuclear periphery,
including transcription; homologous to human SEC13;
abundance increases under DNA replication stress"
/codon_start=1
/product="Sec13p"
/protein_id="NP_013309.1"
/db_xref="GI:6323237"
/db_xref="SGD:S000004198"
/db_xref="GeneID:850905"
/translation="MVVIANAHNELIHDAVLDYYGKRLATCSSDKTIKIFEVEGETHK
LIDTLTGHEGPVWRVDWAHPKFGTILASCSYDGKVLIWKEENGRWSQIAVHAVHSASV
NSVQWAPHEYGPLLLVASSDGKVSVVEFKENGTTSPIIIDAHAIGVNSASWAPATIEE
DGEHNGTKESRKFVTGGADNLVKIWKYNSDAQTYVLESTLEGHSDWVRDVAWSPTVLL
RSYLASVSQDRTCIIWTQDNEQGPWKKTLLKEEKFPDVLWRASWSLSGNVLALSGGDN
KVTLWKENLEGKWEPAGEVHQ"
gene complement(560797..561732)
/gene="PNP1"
/locus_tag="YLR209C"
/db_xref="GeneID:850906"
mRNA complement(560797..561732)
/gene="PNP1"
/locus_tag="YLR209C"
/product="purine-nucleoside phosphorylase"
/transcript_id="NM_001182096.1"
/db_xref="GI:296146746"
/db_xref="GeneID:850906"
CDS complement(560797..561732)
/gene="PNP1"
/locus_tag="YLR209C"
/EC_number="2.4.2.1"
/note="Purine nucleoside phosphorylase, specifically
metabolizes inosine and guanosine nucleosides; involved in
the nicotinamide riboside salvage pathway"
/codon_start=1
/product="purine-nucleoside phosphorylase"
/protein_id="NP_013310.1"
/db_xref="GI:6323238"
/db_xref="SGD:S000004199"
/db_xref="GeneID:850906"
/translation="MSDILNVSQQREAITKAAAYISAILEPHFKNTTNFEPPRTLIIC
GSGLGGISTKLSRDNPPPVTVPYQDIPGFKKSTVPGHSGTLMFGSMNGSPVVLMNGRL
HGYEGNTLFETTFPIRVLNHMGHVRNLIVTNAAGGINAKYQACDLMCIYDHLNIPGLA
GQHPLRGPNLDEDGPRFLALSDAYDLELRKLLFKKWKELKIQRPLHEGTYTFVSGPTF
ETRAESKMIRMLGGDAVGMSTVPEVIVARHCGWRVLALSLITNTCVVDSPASALDESP
VPLEKGKATHAEVLENGKIASNDVQNLIAAVMGEL"
gene 562008..563390
/gene="CLB4"
/locus_tag="YLR210W"
/db_xref="GeneID:850907"
mRNA 562008..563390
/gene="CLB4"
/locus_tag="YLR210W"
/product="Clb4p"
/transcript_id="NM_001182097.1"
/db_xref="GI:296146747"
/db_xref="GeneID:850907"
CDS 562008..563390
/gene="CLB4"
/locus_tag="YLR210W"
/note="B-type cyclin involved in cell cycle progression;
activates Cdc28p to promote the G2/M transition; may be
involved in DNA replication and spindle assembly;
accumulates during S phase and G2, then targeted for
ubiquitin-mediated degradation"
/codon_start=1
/product="Clb4p"
/protein_id="NP_013311.1"
/db_xref="GI:6323239"
/db_xref="SGD:S000004200"
/db_xref="GeneID:850907"
/translation="MMLEGYTVQPPQSTLIGDIEIQDENANQEVKNVLYQGVQKGIKR
LEKRQRRVALGDVTSQKANKIHNAIHNKFHQTKNNFEIENIRSSALVKEQQRDVRHED
SDYFLIDSSEGSSTDDEQVNEDAIDDLLSRRVNDQQIQADEVYEDFDGEMQDVIEEDV
DSQIEPLSPINNDEIQTELDRAFEKYFRSVPNPLDDDTHDVVMVVEYASDIFYYLREL
EVKYRPNPYYMQNQVELTWPFRRTMIDWLVQLHFRFQLLPETLYLTINIVDRFLSKKT
VTLNRFQLVGVSALFIAAKFEEINCPTLDDLVYMLENTYTRDDIIRAEQYMIDTLEFE
IGWPGPMPFLRRISKADDYDFEPRTLAKYLLETTIVEPKLVAAAPSWLAAGAYFLSRT
ILGSNDWSLKHVFYSGYTSSQIIPLASLILENCKNASRRHHSIWKKYFDQKHYRCSQI
VEEWIVSTEA"
gene complement(563792..564531)
/locus_tag="YLR211C"
/db_xref="GeneID:850908"
mRNA complement(join(563792..564454,564514..564531))
/locus_tag="YLR211C"
/product="hypothetical protein"
/transcript_id="NM_001182098.1"
/db_xref="GI:296146748"
/db_xref="GeneID:850908"
CDS complement(join(563792..564454,564514..564531))
/locus_tag="YLR211C"
/note="hypothetical protein; green fluorescent protein
(GFP)-fusion protein localizes to the cytoplasm; YLR211C
is not an essential gene; ORF contains an intron"
/codon_start=1
/product="hypothetical protein"
/protein_id="NP_013312.2"
/db_xref="GI:9755338"
/db_xref="SGD:S000004201"
/db_xref="GeneID:850908"
/translation="MSTLAEVYTIIEDAEQECRKGDFTNAKAKYQEAIEVLGPQNENL
SQNKLSSDVTQAIDLLKQDITAKIQELELLIEKQSSEENNIGMVNNNMLIGSVILNNK
SPINGISNARNWDNPAYQDTLSPINDPLLMSILNRLQFNLNNDIQLKTEGGKNSKNSE
MKINLRLEQFKKELVLYEQKKFKEYGMKIDEITKENKKLANEIGRLRERWDSLVESAK
QRRDKQKN"
gene complement(564860..566281)
/gene="TUB4"
/locus_tag="YLR212C"
/db_xref="GeneID:850909"
mRNA complement(564860..566281)
/gene="TUB4"
/locus_tag="YLR212C"
/product="Tub4p"
/transcript_id="NM_001182099.1"
/db_xref="GI:296146749"
/db_xref="GeneID:850909"
CDS complement(564860..566281)
/gene="TUB4"
/locus_tag="YLR212C"
/note="Gamma-tubulin; involved in nucleating microtubules
from both the cytoplasmic and nuclear faces of the spindle
pole body; protein abundance increases in response to DNA
replication stress"
/codon_start=1
/product="Tub4p"
/protein_id="NP_013313.1"
/db_xref="GI:6323241"
/db_xref="SGD:S000004202"
/db_xref="GeneID:850909"
/translation="MGGEIITLQAGQCGNHVGKFLWSQLAKEHAIGTDGLSQLPDSST
ERDDDTKPFFRENSRNKFTPRAIMMDSEPSVIADVENTFRGFFDPRNTWVASDGASAG
NSWANGYDIGTRNQDDILNKIDKEIDSTDNFEGFQLLHSVAGGTGSGLGSNLLEALCD
RYPKKILTTYSVFPARSSEVVVQSYNTILALRRLIEDSDATVVFDNASLLNISGKVFR
NPNIDLQHTNQLISTIISSVTNSIRFPSYMYSSMSSIYSTLIPSPELHFLSPSFTPFT
SDYIHDDIAHKGHSSYDVMLDLLDPSNSLVSTAMNNPTYFNVYNTIIGNVEPRQISRA
MTKLQQRIKFPSWSSSAMHVNIGRRSPYLPLQPNENEVSGMMLSNMSTVVNVFENACN
TFDKVFAKGAFLNNYNVGDLFQSMQNVQDEFAESREVVQSLMEDYVAAEQDSYLDDVL
VDDENMVGELEEDLDADGDHKLV"
gene complement(566654..567922)
/gene="CRR1"
/locus_tag="YLR213C"
/db_xref="GeneID:850910"
mRNA complement(566654..567922)
/gene="CRR1"
/locus_tag="YLR213C"
/product="Crr1p"
/transcript_id="NM_001182100.1"
/db_xref="GI:296146750"
/db_xref="GeneID:850910"
CDS complement(566654..567922)
/gene="CRR1"
/locus_tag="YLR213C"
/EC_number="3.2.-.-"
/note="Putative glycoside hydrolase of the spore wall
envelope; required for normal spore wall assembly,
possibly for cross-linking between the glucan and chitosan
layers; expressed during sporulation"
/codon_start=1
/product="Crr1p"
/protein_id="NP_013314.1"
/db_xref="GI:6323242"
/db_xref="SGD:S000004203"
/db_xref="GeneID:850910"
/translation="MRISILQLVPVVGYIGFALGELYKPKNSISCSPNNPCPAEWPCC
SPYNECGAGPICVGGCNVRSSFDEESCAPIPALVASQKLEFVSTPKVPKFIVNYQPKP
PIREGNGPNKANTKVGVVEGELNSKRIIHYAKFLVTPDSKEAEKMLEDFDFTHSGYTS
IEASSGNIVLAMPKKTTGSLITSTRSFLYGKASVRMKTARSRGVVTAFDLTSAIGDEI
DFEWLGGDLMTAQSNYYSQGHLDYTRMQRFPVGADTWATYHTYEIDWDPDRIIWYVDG
KIARTVLKKDTWDPISKEYRYPQTPMRLEIAVWPGGSETNGPGTINWAGGLIDWENSP
DIIEKGQFTAHVEQITVTPYQNKFTEQVQFCIKAKKKAPTFSQKDLSRVVVSYNRQDR
LNHHDEGSLKWDCFVTPKINDWLSSWKRSK"
gene 568567..570627
/gene="FRE1"
/locus_tag="YLR214W"
/db_xref="GeneID:850911"
mRNA 568567..570627
/gene="FRE1"
/locus_tag="YLR214W"
/product="Fre1p"
/transcript_id="NM_001182101.1"
/db_xref="GI:296146751"
/db_xref="GeneID:850911"
CDS 568567..570627
/gene="FRE1"
/locus_tag="YLR214W"
/EC_number="1.16.1.7"
/note="Ferric reductase and cupric reductase, reduces
siderophore-bound iron and oxidized copper prior to uptake
by transporters; expression induced by low copper and iron
levels"
/codon_start=1
/product="Fre1p"
/protein_id="NP_013315.1"
/db_xref="GI:6323243"
/db_xref="SGD:S000004204"
/db_xref="GeneID:850911"
/translation="MVRTRVLFCLFISFFATVQSSATLISTSCISQAALYQFGCSSKS
KSCYCKNINWLGSVTACAYENSKSNKTLDSALMKLASQCSSIKVYTLEDMKNIYLNAS
NYLRAPEKSDKKTVVSQPLMANETAYHYYYEENYGIHLNLMRSQWCAWGLVFFWVAVL
TAATILNILKRVFGKNIMANSVKKSLIYPSVYKDYNERTFYLWKRLPFNFTTRGKGLV
VLIFVILTILSLSFGHNIKLPHPYDRPRWRRSMAFVSRRADLMAIALFPVVYLFGIRN
NPFIPITGLSFSTFNFYHKWSAYVCFMLAVVHSIVMTASGVKRGVFQSLVRKFYFRWG
IVATILMSIIIFQSEKVFRNRGYEIFLLIHKAMNIMFIIAMYYHCHTLGWMGWIWSMA
GILCFDRFCRIVRIIMNGGLKTATLSTTDDSNVIKISVKKPKFFKYQVGAFAYMYFLS
PKSAWFYSFQSHPFTVLSERHRDPNNPDQLTMYVKANKGITRVLLSKVLSAPNHTVDC
KIFLEGPYGVTVPHIAKLKRNLVGVAAGLGVAAIYPHFVECLRLPSTDQLQHKFYWIV
NDLSHLKWFENELQWLKEKSCEVSVIYTGSSVEDTNSDESTKGFDDKEESEITVECLN
KRPDLKELVRSEIKLSELENNNITFYSCGPATFNDDFRNAVVQGIDSSLKIDVELEEE
SFTW"
gene complement(570776..571858)
/gene="CDC123"
/locus_tag="YLR215C"
/db_xref="GeneID:850912"
mRNA complement(570776..571858)
/gene="CDC123"
/locus_tag="YLR215C"
/product="Cdc123p"
/transcript_id="NM_001182102.1"
/db_xref="GI:296146752"
/db_xref="GeneID:850912"
CDS complement(570776..571858)
/gene="CDC123"
/locus_tag="YLR215C"
/note="Protein involved in nutritional control of the cell
cycle; regulates abundance of the translation initiation
factor eIF2; ortholog of human D123 protein"
/codon_start=1
/product="Cdc123p"
/protein_id="NP_013316.1"
/db_xref="GI:6323244"
/db_xref="SGD:S000004205"
/db_xref="GeneID:850912"
/translation="MSSQEYTTFIDIPVTRAQVEHCSYSFWSSLYPKYVPKSIVLKSL
PKKFIQYLEQDGIKLPQEENSRSVYTEEIIRNEDNDYSDWEDDEDTATEFVQEVEPLI
DFPELHQKLKDALNELGAVAPKLNWSAPRDATWILPNNTMKCNEVNELYLLLNASNYI
MHDLQRAFKGCVDGDDIKGLKFDLVLRQWCDMNPALEFRVFVKNAHIVGATQRDLNYY
DYLDELSDTFKDLIDEIVHDVVLPKFPDKSFVLDVYIPRPFNKIFIVDINPFARKTDS
LLFSWNEIAAIAPPKNDVEDYELRLVTRHNTGRFASKEHSENHVPQDLVEASLNPEAI
RELTQKWKELLSQQAKEESSDSENET"
gene complement(572096..573211)
/gene="CPR6"
/locus_tag="YLR216C"
/gene_synonym="CYP40"
/db_xref="GeneID:850914"
mRNA complement(572096..573211)
/gene="CPR6"
/locus_tag="YLR216C"
/gene_synonym="CYP40"
/product="peptidylprolyl isomerase CPR6"
/transcript_id="NM_001182103.1"
/db_xref="GI:296146753"
/db_xref="GeneID:850914"
CDS complement(572096..573211)
/gene="CPR6"
/locus_tag="YLR216C"
/gene_synonym="CYP40"
/EC_number="5.2.1.8"
/note="Peptidyl-prolyl cis-trans isomerase (cyclophilin);
catalyzes the cis-trans isomerization of peptide bonds
N-terminal to proline residues; binds to Hsp82p and
contributes to chaperone activity; protein abundance
increases in response to DNA replication stress"
/codon_start=1
/product="peptidylprolyl isomerase CPR6"
/protein_id="NP_013317.1"
/db_xref="GI:6323246"
/db_xref="SGD:S000004206"
/db_xref="GeneID:850914"
/translation="MTRPKTFFDISIGGKPQGRIVFELYNDIVPKTAENFLKLCEGNA
GMAKTKPDVPLSYKGSIFHRVIKDFMCQFGDFTNFNGTGGESIYDEKFEDENFTVKHD
KPFLLSMANAGPNTNGSQAFITCVPTPHLDGKHVVFGEVIQGKRIVRLIENQQCDQEN
NKPLRDVKIDDCGVLPDDYQVPENAEATPTDEYGDNYEDVLKQDEKVDLKNFDTVLKA
IETVKNIGTEQFKKQNYSVALEKYVKCDKFLKEYFPEDLEKEQIEKINQLKVSIPLNI
AICALKLKDYKQVLVASSEVLYAEAADEKAKAKALYRRGLAYYHVNDTDMALNDLEMA
TTFQPNDAAILKAIHNTKLKRKQQNEKAKKSLSKMFS"
gene complement(573466..573918)
/gene="COA4"
/locus_tag="YLR218C"
/gene_synonym="CMC3"
/db_xref="GeneID:850915"
mRNA complement(573466..573918)
/gene="COA4"
/locus_tag="YLR218C"
/gene_synonym="CMC3"
/product="Coa4p"
/transcript_id="NM_001182105.1"
/db_xref="GI:296146754"
/db_xref="GeneID:850915"
CDS complement(573466..573918)
/gene="COA4"
/locus_tag="YLR218C"
/gene_synonym="CMC3"
/note="Twin Cx(9)C protein involved in cytochrome c
oxidase assembly or stability; localizes to the
mitochondrial intermembrane space via the Mia40p-Erv1p
system; interacts genetically with CYC1 and with
cytochrome c oxidase assembly factors"
/codon_start=1
/product="Coa4p"
/protein_id="NP_013319.1"
/db_xref="GI:6323247"
/db_xref="SGD:S000004208"
/db_xref="GeneID:850915"
/translation="MLLFSSFFSHNKCPKQKKGPQPLKVVKGTSKSCAKQGKIKGKEK
LWQAKTGRLVMSETGETSEYYKQALEEYKEVQEDEDPDVWDTRISKTGCYVENLALQL
CHAETGDWRQCFNEMALFRKCWEKNGNRERVSTVDVDGTTSKDSEKKK"
gene 574151..576337
/gene="MSC3"
/locus_tag="YLR219W"
/db_xref="GeneID:850916"
mRNA 574151..576337
/gene="MSC3"
/locus_tag="YLR219W"
/product="Msc3p"
/transcript_id="NM_001182106.1"
/db_xref="GI:296146755"
/db_xref="GeneID:850916"
CDS 574151..576337
/gene="MSC3"
/locus_tag="YLR219W"
/note="hypothetical protein; green fluorescent protein
(GFP)-fusion protein localizes to the cell periphery; msc3
mutants are defective in directing meiotic recombination
events to homologous chromatids; potential Cdc28p
substrate; protein abundance increases in response to DNA
replication stress"
/codon_start=1
/product="Msc3p"
/protein_id="NP_013320.1"
/db_xref="GI:6323248"
/db_xref="SGD:S000004209"
/db_xref="GeneID:850916"
/translation="MVFGFTKRDRRVPDLSRYDYYYQNHEDYNKSPQLSAAAASAASA
ASPDRTNYSRSHSLVSHAPSIPRQRSSVKSPGRRLSTSSAAPPTSRAAAKQYSQKTYS
LRSQRSGEYHLHPPGYTTNGSRMNSMTSGANVRRNYGKNKSTAGNNNDSRANSITVKT
TQVTDPSGRTQSITKKTIRKINGYEYVETTTTTKNLVPLGDSQRHFDEFSENYMLQDD
DILEEQASDNIHDIIEENETDNEKPYSPVSESHLQDDSELNVEKPDFPLGSYFHHKYS
TDVMPLEEESSLSNFSDALDYIPPTHQTSSKYIHNKRKQASTTRRKKRPPAVKNAEAE
AKKPLTEAEMYLKALEVAKRNVYHTDAASDNASAPLGSNKSRKSRMGQKMTLRSSSDS
PTATANLVKSNVEVQPKRFTSSFFSRNTKSAPHEVHNHSVSTHFKSNKAVDPVPEPKS
ANTGLTDKEMYDQALKIAQARYYNSHGIQPEAVDNSTTAAKPRQVGVSHLGSTGSIPP
NEQHYLGDSEIPVQSEVHEYEPIPLQKTKTTGSSKNKFKTMFDKVLQFSQENYGYQHK
KEQGEQTPVTRNAEESFPAASISEGVTTAKPSSNEGVMTNPVVTDSPSPLQQQIDSTT
ASSNGQSQGNVPTSAVASTTRTRSPELQDNLKSSSSLLQDQTPQRQEDATDPTTSSTN
ELSAAEPTMVTSTHATKTIQAQTQDPPTKHKKSSFFTKLFKKKSSR"
gene 576825..577793
/gene="CCC1"
/locus_tag="YLR220W"
/db_xref="GeneID:850917"
mRNA 576825..577793
/gene="CCC1"
/locus_tag="YLR220W"
/product="Ccc1p"
/transcript_id="NM_001182107.1"
/db_xref="GI:296146756"
/db_xref="GeneID:850917"
CDS 576825..577793
/gene="CCC1"
/locus_tag="YLR220W"
/note="Putative vacuolar Fe2+/Mn2+ transporter; suppresses
respiratory deficit of yfh1 mutants, which lack the
ortholog of mammalian frataxin, by preventing
mitochondrial iron accumulation; relative distribution to
the vacuole decreases upon DNA replication stress"
/codon_start=1
/product="Ccc1p"
/protein_id="NP_013321.1"
/db_xref="GI:6323249"
/db_xref="SGD:S000004210"
/db_xref="GeneID:850917"
/translation="MSIVALKNAVVTLIQKAKGSGGTSELGGSESTPLLRGSNSNSSR
HDNLSSSSSDIIYGRNSAQDLENSPMSVGKDNRNGDNGSDNEKANLGFFQSVDPRVIS
DLIIGLSDGLTVPFALTAGLSSLGDAKLVITGGFAELISGAISMGLGGYLGAKSESDY
YHAEVKKEKRKFYDNSNLINREIEDILLEINPNFSDETIVSFIKDLQRTPELMVDFII
RYGRGLDEPAENRELISAVTIGGGYLLGGLVPLVPYFFVSDVGTGLIYSIIVMVVTLF
WFGYVKTKLSMGSGSSTSKKVTEGVEMVVVGGVAAGAAWFFVKLLG"
gene complement(578362..579024)
/gene="RSA3"
/locus_tag="YLR221C"
/db_xref="GeneID:850918"
mRNA complement(578362..579024)
/gene="RSA3"
/locus_tag="YLR221C"
/product="Rsa3p"
/transcript_id="NM_001182108.1"
/db_xref="GI:296146757"
/db_xref="GeneID:850918"
CDS complement(578362..579024)
/gene="RSA3"
/locus_tag="YLR221C"
/note="Protein with a likely role in ribosomal maturation,
required for accumulation of wild-type levels of large
(60S) ribosomal subunits; binds to the helicase Dbp6p in
pre-60S ribosomal particles in the nucleolus"
/codon_start=1
/product="Rsa3p"
/protein_id="NP_013322.1"
/db_xref="GI:6323250"
/db_xref="SGD:S000004211"
/db_xref="GeneID:850918"
/translation="MSAGDISAINIKSVKKNRRRKKRRTADVSSSDSSSSDPSSESEK
EEIQNGAIEEHVGENGKSDHVFSKGNDEDKQEDIAIEVSDVELTDEESKDLKLNSKEV
IDDLTKISLSKIPEPTKSQNKEGFMNASKIAENIKLAREEYNELAENFVPKGKDKTKL
REEYLNLLFENYGDDINRLRAAPDFTNKSLSILADALQEGIGMFDIGELELVLKNKEM
EN"
gene complement(579318..581771)
/gene="UTP13"
/locus_tag="YLR222C"
/db_xref="GeneID:850919"
mRNA complement(579318..581771)
/gene="UTP13"
/locus_tag="YLR222C"
/product="Utp13p"
/transcript_id="NM_001182109.1"
/db_xref="GI:296146758"
/db_xref="GeneID:850919"
CDS complement(579318..581771)
/gene="UTP13"
/locus_tag="YLR222C"
/note="Nucleolar protein, component of the small subunit
(SSU) processome containing the U3 snoRNA that is involved
in processing of pre-18S rRNA"
/codon_start=1
/product="Utp13p"
/protein_id="NP_013323.1"
/db_xref="GI:6323251"
/db_xref="SGD:S000004212"
/db_xref="GeneID:850919"
/translation="MDLKTSYKGISLNPIYAGSSAVATVSENGKILATPVLDEINIID
LTPGSRKILHKISNEDEQEITALKLTPDGQYLTYVSQAQLLKIFHLKTGKVVRSMKIS
SPSYILDADSTSTLLAVGGTDGSIIVVDIENGYITHSFKGHGGTISSLKFYGQLNSKI
WLLASGDTNGMVKVWDLVKRKCLHTLQEHTSAVRGLDIIEVPDNDEPSLNLLSGGRDD
IINLWDFNMKKKCKLLKTLPVNQQVESCGFLKDGDGKRIIYTAGGDAIFQLIDSESGS
VLKRTNKPIEELFIIGVLPILSNSQMFLVLSDQTLQLINVEEDLKNDEDTIQVTSSIA
GNHGIIADMRYVGPELNKLALATNSPSLRIIPVPDLSGPEASLPLDVEIYEGHEDLLN
SLDATEDGLWIATASKDNTAIVWRYNENSCKFDIYAKYIGHSAAVTAVGLPNIVSKGY
PEFLLTASNDLTIKKWIIPKPTASMDVQIIKVSEYTRHAHEKDINALSVSPNDSIFAT
ASYDKTCKIWNLENGELEATLANHKRGLWDVSFCQYDKLLATSSGDKTVKIWSLDTFS
VMKTLEGHTNAVQRCSFINKQKQLISCGADGLIKIWDCSSGECLKTLDGHNNRLWALS
TMNDGDMIVSADADGVFQFWKDCTEQEIEEEQEKAKLQVEQEQSLQNYMSKGDWTNAF
LLAMTLDHPMRLFNVLKRALGESRSRQDTEEGKIEVIFNEELDQAISILNDEQLILLM
KRCRDWNTNAKTHTIAQRTIRCILMHHNIAKLSEIPGMVKIVDAIIPYTQRHFTRVDN
LVEQSYILDYALVEMDKLF"
gene complement(582233..585490)
/gene="IFH1"
/locus_tag="YLR223C"
/db_xref="GeneID:850920"
mRNA complement(582233..585490)
/gene="IFH1"
/locus_tag="YLR223C"
/product="Ifh1p"
/transcript_id="NM_001182110.1"
/db_xref="GI:296146759"
/db_xref="GeneID:850920"
CDS complement(582233..585490)
/gene="IFH1"
/locus_tag="YLR223C"
/note="Coactivator that regulates transcription of
ribosomal protein (RP) genes; recruited to RP gene
promoters during optimal growth conditions via Fhl1p;
subunit of CURI, a complex that coordinates RP production
and pre-rRNA processing"
/codon_start=1
/product="Ifh1p"
/protein_id="NP_013324.1"
/db_xref="GI:6323252"
/db_xref="SGD:S000004213"
/db_xref="GeneID:850920"
/translation="MAGKKSPRKSTINHSTHSGKLPANIKRLIKKGESDTKSRQSPPT
LSTTRPRRFSLIYSSESSLSDVSDSDKNKSTNPHKIKRKAKNISNNSQGKKSKLIQRQ
IDNDDEGTESSDYQAVTDGEESENEEEESEEEEEDDDEDDDDDDDDGSDSDSDSETSS
DDENIDFVKLTAQRKKRAMKALSAMNTNSNTLYSSRENSNKNKSVKLSPKKENEEEQK
EEKEKEKEEQQKQQESNKKEVNGSGTTTTQQALSFKFKKEDDGISFGNGNEGYNEDIG
EEVLDLKNKENNGNEEDKLDSKVMLGNNDELRFPNISESDESEYDIDQDAYFDVINNE
DSHGEIGTDLETGEDDLPILEEEEQNIVSELQNDDELSFDGSIHEEGSDPVEDAENKF
LQNEYNQENGYDEEDDEEDEIMSDFDMPFYEDPKFANLYYYGDGSEPKLSLSTSLPLM
LNDEKLSKLKKKEAKKREQEERKQRRKLYKKTQKPSTRTTSNVDNDEYIFNVFFQSDD
ENSGHKSKKGRHKSGKSHIEHKNKGSNLIKSNDDLEPSTHSTVLNSGKYDSSDDEYDN
ILLDVAHMPSDDECSESETSHDADTDEELRALDSDSLDIGTELDDDYEDDDDDSSVTN
VFIDIDDLDPDSFYFHYDSDGSSSLISSNSDKENSDGSKDCKHDLLETVVYVDDESTD
EDDNLPPPSSRSKNIGSKAKEIVSSNVVGLRPPKLGTWETDNKPFSIIDGLSTKSLYA
LIQEHQQLREQHQRAQTPDVKREGSSNGNNGDELTLNELLNMSELEDDSPSHTDDMEN
NYNDAINSKSTNGHAADWYEVPKVPLSAFRNKGINAYEEDEYMIPANSNRKVPIGYIG
NERTRKKIDKMKELQRKKTEKKRQLKKKKKLLKIRKQRQKAIKEQETMNLQLGINGHE
IIGNNNSHSDINTGTDFTTNENTPMNELPSHAPEDASLIPHNSDLAVDSNTRKNSTKS
VGLDEIHEILGKDENDLLSVGDINGYDAQEGHVIEDTDADILASLTAPVQFDNTLSHE
NSNSMWRRRQSMVEAAAENLRFTKNGLFSESALADIEGIMGNDVNHSFEFNDVLQ"
gene 586464..587573
/locus_tag="YLR224W"
/db_xref="GeneID:850921"
mRNA 586464..587573
/locus_tag="YLR224W"
/product="hypothetical protein"
/transcript_id="NM_001182111.1"
/db_xref="GI:296146760"
/db_xref="GeneID:850921"
CDS 586464..587573
/locus_tag="YLR224W"
/note="F-box protein and component of SCF ubiquitin ligase
complexes involved in ubiquitin-dependent protein
catabolism; readily monoubiquitinated in vitro by SCF-Ubc4
complexes; YLR224W is not an essential gene"
/codon_start=1
/product="hypothetical protein"
/protein_id="NP_013325.1"
/db_xref="GI:6323253"
/db_xref="SGD:S000004214"
/db_xref="GeneID:850921"
/translation="MNQSDSSLMDLPLEIHLSLLEYVPNELRAVNKYFYVLHNHSYKE
KSLAWIAEDNYIWAVVKHSLCLYVKSLDPLRQHAREIIQETKEPGFNVPLCMTKYIAD
SWYIVYNALQYPGKIINMGWDKYTKSQDSNGSDSTSNFNSRPKERTLMQSLTALPVNF
WSRRKDEPTPVNVWFYVKNAHVARYIPKIITEIGICNYGPKQIVASAGYINELITSEG
IYCVNLGHLPRLYDEQIFEGTGTTHLPLELKAIDRTDSDVCINGDLVLLGYDFIPYQI
SKPWLLFRIEPVNSIEAIFNYSECSFSYQFAWSLACLQSEEKISFPRDTIIGHGLPYK
PSKLIRIFVYKHPEQKQDLGQEIALPNWNTPYLRR"
gene complement(587695..588918)
/locus_tag="YLR225C"
/db_xref="GeneID:850922"
mRNA complement(587695..588918)
/locus_tag="YLR225C"
/product="hypothetical protein"
/transcript_id="NM_001182112.1"
/db_xref="GI:296146761"
/db_xref="GeneID:850922"
CDS complement(587695..588918)
/locus_tag="YLR225C"
/note="hypothetical protein; green fluorescent protein
(GFP)-fusion protein localizes to the cytoplasm; YLR225C
is not an essential gene"
/codon_start=1
/product="hypothetical protein"
/protein_id="NP_013326.1"
/db_xref="GI:6323254"
/db_xref="SGD:S000004215"
/db_xref="GeneID:850922"
/translation="MAVAIKKEKTKFAPVKEVLSEKDHANYTKFQDTSKLEWFCRTSN
HKKFKSHSLLKAVRNPTETRIETQTLYFTDLTNGKCGLIQLLYSSVMGGIYKGFQLNF
KIFKASSEENSEEDIDIWESFKIDNIKDFDTLKVESDNVTFHFVPLENSSSSGFAQLL
IKIDIPKGSTSCLLKDLKVDITVNLQEGFIINPDGSNYYLDKSISLEELAKRDSSSTS
RKMIRHVFVPRGFCNGTISYKKNDKPVKLDLKDTPMLYLDAVQGLIPNKAASKWNFLC
FNGEKRSMMCIEFTTTKEYGSTTVTIWAVSDKDKILEVGSSVNDHAVKFPSTKEDKQN
GWKYPTSISFPRGFEESNLRLVNRYDIMSELPAFIRSIAENLANMKPFIYQFCQKSKF
DDDEGVSIIESTFIN"
gene 589354..590541
/gene="BUR2"
/locus_tag="YLR226W"
/gene_synonym="CST4"
/db_xref="GeneID:850923"
mRNA 589354..590541
/gene="BUR2"
/locus_tag="YLR226W"
/gene_synonym="CST4"
/product="Bur2p"
/transcript_id="NM_001182113.1"
/db_xref="GI:296146762"
/db_xref="GeneID:850923"
CDS 589354..590541
/gene="BUR2"
/locus_tag="YLR226W"
/gene_synonym="CST4"
/note="Cyclin for the Sgv1p (Bur1p) protein kinase; Sgv1p
and Bur2p comprise a CDK-cyclin complex involved in
transcriptional regulation through its phosphorylation of
the carboxy-terminal domain of the largest subunit of RNA
polymerase II"
/codon_start=1
/product="Bur2p"
/protein_id="NP_013327.1"
/db_xref="GI:6323255"
/db_xref="SGD:S000004216"
/db_xref="GeneID:850923"
/translation="MSATSSSGDVKKFQAVPKPTSNASPPPASSGFNARTLWPDLIET
PENQWVFECKDIIEKIGTNGPIAVEIKKNMEKCLMYFYTLKKKLNLFDHTYTASCILF
YRYWFIYGIPTAITECIHISQGILVTACKTMENNRPIEAYIKATCEFLMQNIPSLKSR
TNIDKLKWEFRDKLVTNEKKILCLFGFDLNISNPKELIEEVFSGYYRFNRDHNLPENF
KKAFPKILQESRNFMVQAVTQPVSLLCDGYTFIVLSLIYCGLEYKKLVDKDFRYPKNF
FKDRFPIEVTPENFANIFTDYKLLEENFFNLKSNKGAKLQIDSSMIDSVIDESGDVEN
EVSEISDPFNYELIKSGEVKEEFLNHIETRVKDLLDKAKQESMKRKAKDPIRTPDAKK
PKI"
gene complement(590562..592043)
/gene="ADY4"
/locus_tag="YLR227C"
/db_xref="GeneID:850924"
mRNA complement(590562..592043)
/gene="ADY4"
/locus_tag="YLR227C"
/product="Ady4p"
/transcript_id="NM_001182114.1"
/db_xref="GI:296146763"
/db_xref="GeneID:850924"
CDS complement(590562..592043)
/gene="ADY4"
/locus_tag="YLR227C"
/note="Structural component of the meiotic outer plaque,
which is a membrane-organizing center that assembles on
the cytoplasmic face of the spindle pole body during
meiosis II and triggers the formation of the prospore
membrane"
/codon_start=1
/product="Ady4p"
/protein_id="NP_013328.1"
/db_xref="GI:6323256"
/db_xref="SGD:S000004217"
/db_xref="GeneID:850924"
/translation="MNKDVDYQTFKKSLRKEFKKAVKTILNLQAYNGDLIRDFLALYI
PYHVVFYNLSIMKKGSPLRIQTNNLLKEALAKILNFNLAMGPKHIIKIMKKDKADPET
MNKLKLVLYIKLFQGVFGHVDKNYNLAFQSFRWCLQFIAYSKRTRLFASIADEQIGAF
YELCELFISMLCCHCFLIDLKENEALVGNNLKNFIKRQNPNYSHGFDLNEETKSLQWH
WSLDEVDVIEALYCVAFDAMDKITLKFSKVNENFVFSQFFQYCAEIEEMLAILRGKIW
ECECDVFGPRIGLLVDSNHMNETIQKNILSITFKLKNDPQIICCLNKILEGLLLSSGV
QFKVIQFFYVLKLYYMQDNEYTFEASSEMDKLTIECLCIIENIIDACDNPDEVTDYQL
PKVLLTAMEGKLLVAEKISEDNDCSESLDDYHPRTYQFRHPRIIIDKMKTKLKQKLRF
DSPKDPETDDHWIEYWKYCYQDNIGNLPDILSRIYQTFTDPSN"
gene complement(592519..592619)
/locus_tag="tL(UAG)L1"
/db_xref="GeneID:850925"
tRNA complement(join(592519..592562,592582..592619))
/locus_tag="tL(UAG)L1"
/product="tRNA-Leu"
/note="Leucine tRNA (tRNA-Leu), predicted by tRNAscan-SE
analysis"
/db_xref="SGD:S000006655"
/db_xref="GeneID:850925"
LTR complement(592706..593035)
/note="Ty1 LTR"
/db_xref="SGD:S000007070"
mobile_element 593145..599062
/note="YLRWTy1-2; Ty1 element, LTR retrotransposon of the
Copia (Pseudoviridae) group; contains co-transcribed genes
TYA Gag and TYB Pol, encoding proteins involved in
structure and function of virus-like particles, flanked by
two direct repeats"
/mobile_element_type="retrotransposon:YLRWTy1-2"
/db_xref="SGD:S000007098"
LTR 593145..593478
/note="Ty1 LTR"
/db_xref="SGD:S000007085"
gene 593438..598706
/locus_tag="YLR227W-B"
/db_xref="GeneID:850927"
mRNA join(<593438..594742,594744..>598706)
/locus_tag="YLR227W-B"
/transcript_id="NM_001184408.1"
/db_xref="GI:296146765"
/db_xref="GeneID:850927"
CDS join(593438..594742,594744..598706)
/locus_tag="YLR227W-B"
/EC_number="2.7.7.49"
/EC_number="3.4.23.-"
/EC_number="3.1.26.4"
/EC_number="2.7.7.7"
/ribosomal_slippage
/note="Retrotransposon TYA Gag and TYB Pol genes;
transcribed/translated as one unit; polyprotein is
processed to make a nucleocapsid-like protein (Gag),
reverse transcriptase (RT), protease (PR), and integrase
(IN); similar to retroviral genes"
/codon_start=1
/product="gag-pol fusion protein"
/protein_id="NP_058171.1"
/db_xref="GI:7839187"
/db_xref="SGD:S000007376"
/db_xref="GeneID:850927"
/translation="MESQQLSQHSHISHGSACASVTSKEVHTNQDPLDVSASKTEECE
KASTKANSQQTTTPASSAVPENPHHASPQPASVPPPQNGPYPQQCMMTQNQANPSGWS
FYGHPSMIPYTPYQMSPMYFPPGPQSQFPQYPSSVGTPLSTPSPESGNTFTDSSSADS
DMTSTKKYVRPPPMLTSPNDFPNWVKTYIKFLQNSNLGGIIPTVNGKPVRQITDDELT
FLYNTFQIFAPSQFLPTWVKDILSVDYTDIMKILSKSIEKMQSDTQEANDIVTLANLQ
YNGSTPADAFETKVTNIIDRLNNNGIHINNKVACQLIMRGLSGEYKFLRYTRHRHLNM
TVAELFLDIHAIYEEQQGSRNSKPNYRRNLSDEKNDSRSYTNTTKPKVIARNPQKTNN
SKSKTARAHNVSTSNNSPSTDNDSISKSTTEPIQLNNKHDLHLGQELTESTVNHTNHS
DDELPGHLLLDSGASRTLIRSAHHIHSASSNPDINVVDAQKRNIPINAIGDLQFHFQD
NTKTSIKVLHTPNIAYDLLSLNELAAVDITACFTKNVLERSDGTVLAPIVQYGDFYWV
SKRYLLPSNISVPTINNVHTSESTRKYPYPFIHRMLAHANAQTIRYSLKNNTITYFNE
SDVDWSSAIDYQCPDCLIGKSTKHRHIKGSRLKYQNSYEPFQYLHTDIFGPVHNLPKS
APSYFISFTDETTKFRWVYPLHDRREDSILDVFTTILAFIKNQFQASVLVIQMDRGSE
YTNRTLHKFLEKNGITPCYTTTADSRAHGVAERLNRTLLDDCRTQLQCSGLPNHLWFS
AIEFSTIVRNSLASPKSKKSASQHAGLAGLDISTLLPFGQPVIVNDHNPNSKIHPRGI
PGYALHPSRNSYGYIIYLPSLKKTVDTTNYVILQGKESRLDQFNYDALTFDEDLNRLT
ASYHSFIASNEIQESNDLNIESDHDFQSDIELHPEQPRNVLSKAVSPTDSTPPSTHTE
DSKPISEINLRAPREVDPNISESNILPSKKRSSTPQISNIESTGSGGMHKLNVPLLAP
MSQSNTHESSHASKSKDFRHSDSYSNNETNHTNVPISSTGGTNNKTVPQISDQETEKR
IIHRSPSIDASPPENNSSHNIVPIKTPTTVSEQNTEESIIADLPLPDPPPEPPTELSD
SFKELPPINSRQTNSSLGGIGDSNAYTTINSKKRSLEDNETEIKVSRDTWNTKNMRSL
EPPRSKKRIHLIAAAKAVKSIKPIRTTLRYDEAITYNKDIKEKEKYIEAYHKEVNQLL
KMNTWDTDKYYDRKEIDPKRVINSMFIFNKKRDGTHKARFVARGDIQHPDTYDTGMQS
NTVHHYALMTSLSLALDNNYYITQLDISSAYLYADIKEELYIRPPPHLGMNDKLIRLK
KSHYGLKQSGANWYETIKSYLIKQCGMEEVRGWSCVFKNSQVTICLFVDDMILFSKDL
NANKKIITTLKKQYDTKIINLGESDNEIQYDILGLEIKYQRGKYMKLGMENSLTEKIP
KLNVPLNPKGRKLSAPGQPGLYIDQDELEIDEDEYKEKVHEMQKLIGLASYVGYKFRF
DLLYYINTLAQHILFPSRQVLDMTYELIQFMWDTRDKQLIWHKNKPTEPDNKLVAISD
ASYGNQPYYKSQIGNIFLLNGKVIGGKSTKASLTCTSTTEAEIHAVSEAIPLLNNLSH
LVQELNKKPIIKGLLTDSRSTISIIKSTNEEKFRNRFFGTKAMRLRDEVSGNNLYVYY
IETKKNIADVMTKPLPIKTFKLLTNKWIH"
gene 593438..594760
/locus_tag="YLR227W-A"
/db_xref="GeneID:850926"
mRNA <593438..>594760
/locus_tag="YLR227W-A"
/transcript_id="NM_001184407.1"
/db_xref="GI:296146764"
/db_xref="GeneID:850926"
CDS 593438..594760
/locus_tag="YLR227W-A"
/note="Retrotransposon TYA Gag gene co-transcribed with
TYB Pol; translated as TYA or TYA-TYB polyprotein; Gag is
a nucleocapsid protein that is the structural constituent
of virus-like particles (VLPs); similar to retroviral Gag"
/codon_start=1
/product="gag protein"
/protein_id="NP_058172.1"
/db_xref="GI:7839186"
/db_xref="SGD:S000007375"
/db_xref="GeneID:850926"
/translation="MESQQLSQHSHISHGSACASVTSKEVHTNQDPLDVSASKTEECE
KASTKANSQQTTTPASSAVPENPHHASPQPASVPPPQNGPYPQQCMMTQNQANPSGWS
FYGHPSMIPYTPYQMSPMYFPPGPQSQFPQYPSSVGTPLSTPSPESGNTFTDSSSADS
DMTSTKKYVRPPPMLTSPNDFPNWVKTYIKFLQNSNLGGIIPTVNGKPVRQITDDELT
FLYNTFQIFAPSQFLPTWVKDILSVDYTDIMKILSKSIEKMQSDTQEANDIVTLANLQ
YNGSTPADAFETKVTNIIDRLNNNGIHINNKVACQLIMRGLSGEYKFLRYTRHRHLNM
TVAELFLDIHAIYEEQQGSRNSKPNYRRNLSDEKNDSRSYTNTTKPKVIARNPQKTNN
SKSKTARAHNVSTSNNSPSTDNDSISKSTTEPIQLNNKHDLHLRPGTY"
LTR 598729..599062
/note="Ty1 LTR"
/db_xref="SGD:S000007086"
LTR 599268..599544
/note="Ty1 LTR"
/db_xref="SGD:S000007087"
LTR complement(599570..599844)
/note="Ty4 LTR"
/db_xref="SGD:S000007080"
gene complement(600019..602463)
/gene="ECM22"
/locus_tag="YLR228C"
/db_xref="GeneID:850928"
mRNA complement(600019..602463)
/gene="ECM22"
/locus_tag="YLR228C"
/product="Ecm22p"
/transcript_id="NM_001182115.1"
/db_xref="GI:296146766"
/db_xref="GeneID:850928"
CDS complement(600019..602463)
/gene="ECM22"
/locus_tag="YLR228C"
/note="Sterol regulatory element binding protein;
regulates transcription of sterol biosynthetic genes;
contains Zn[2]-Cys[6] binuclear cluster; relocates from
intracellular membranes to perinuclear foci on sterol
depletion; ECM22 has a paralog, UPC2, that arose from the
whole genome duplication"
/codon_start=1
/product="Ecm22p"
/protein_id="NP_013329.1"
/db_xref="GI:6323257"
/db_xref="SGD:S000004218"
/db_xref="GeneID:850928"
/translation="MTSDDGNAGQEREKDAELIEVGGKKVSKTSTGKRKFHNKSKTGC
DNCKRRRVKCDEGKPFCKKCTNMKLDCVYSPIQPRRRKDSSSSKFASAVHDRVGKKNL
SDNAIMLQQQQQQLHHQQEQQFRQQQQVQLQQQLLPHVGTDEQSNSPNSVPPSVSNNM
ENLLLPHLLASLVNNTSNSTNSSANGAEAHNNITQTAPSSMINNNHPNMALPGNSPLS
IPITPSFQSTAMNLSSSLNGLLSPGRLNSVTNGLQQPQLQQQNQQIPQQQGTQSPFSN
IPFDQLAQLNKMGLNFNMKSFNTLFPYGAANGMASEFQELFGLGKFATSNNRAIKVST
AEEALANMQQEQEDKNKQFTKNPLDNTKTDAVNSGNNPLNGNENKVTASDILSHNKNL
IIDNTGLTISPPHTLSKPSIDQNIASPSTGVSNVTSTKSLLSIPDNRTALGNSPTLKT
SPMGDLLSNSEALSPRSSNSHTQQQSSPHSNASSASRLVPELVGLSRKSNLNLIDLKL
FHHYCTDVWHTITEAGISGPEVWSTYIPDLAFHFPFLMHTILAFSATHLSRTEAGLDN
YVSSHRLEALRLLREAVLEISDDNTDALVASALILILDSLANASSSSPTAWIFHVKGA
VTILTAVWPLSETSKFYNLISVDLSDLGEAVINQSNHNNDNDNSNNGDGNNNNTISEL
VCFDESIADLYPVEIDSPYLITLAYLDKLHREKNQLDFMLRVFSFPALLDRTFLALLM
TGDLGAMRIMRSYYTLLRGYTTEIKDKVWFLDSVSQVLPQDVDEYSGGGGMHMMLDFL
GGGLPSMTTTNFSAFM"
rep_origin 602939..603155
/note="ARS1218;
Autonomously Replicating Sequence"
/db_xref="SGD:S000118477"
gene complement(604212..604787)
/gene="CDC42"
/locus_tag="YLR229C"
/db_xref="GeneID:850930"
mRNA complement(604212..604787)
/gene="CDC42"
/locus_tag="YLR229C"
/product="Cdc42p"
/transcript_id="NM_001182116.1"
/db_xref="GI:296146767"
/db_xref="GeneID:850930"
CDS complement(604212..604787)
/gene="CDC42"
/locus_tag="YLR229C"
/note="Small rho-like GTPase, essential for establishment
and maintenance of cell polarity; mutants have defects in
the organization of actin and septins"
/codon_start=1
/product="Cdc42p"
/protein_id="NP_013330.1"
/db_xref="GI:6323259"
/db_xref="SGD:S000004219"
/db_xref="GeneID:850930"
/translation="MQTLKCVVVGDGAVGKTCLLISYTTNQFPADYVPTVFDNYAVTV
MIGDEPYTLGLFDTAGQEDYDRLRPLSYPSTDVFLVCFSVISPPSFENVKEKWFPEVH
HHCPGVPCLVVGTQIDLRDDKVIIEKLQRQRLRPITSEQGSRLARELKAVKYVECSAL
TQRGLKNVFDEAIVAALEPPVIKKSKKCAIL"
gene complement(605300..605432)
/locus_tag="tI(UAU)L"
/db_xref="GeneID:850931"
tRNA complement(join(605300..605335,605396..605432))
/locus_tag="tI(UAU)L"
/product="tRNA-Ile"
/note="Isoleucine tRNA (tRNA-Ile), predicted by
tRNAscan-SE analysis"
/db_xref="SGD:S000006614"
/db_xref="GeneID:850931"
gene complement(605758..607119)
/gene="BNA5"
/locus_tag="YLR231C"
/db_xref="GeneID:850933"
mRNA complement(605758..607119)
/gene="BNA5"
/locus_tag="YLR231C"
/product="kynureninase"
/transcript_id="NM_001182118.1"
/db_xref="GI:296146768"
/db_xref="GeneID:850933"
CDS complement(605758..607119)
/gene="BNA5"
/locus_tag="YLR231C"
/EC_number="3.7.1.3"
/note="Kynureninase, required for the de novo biosynthesis
of NAD from tryptophan via kynurenine; expression
regulated by Hst1p"
/codon_start=1
/product="kynureninase"
/protein_id="NP_013332.1"
/db_xref="GI:6323261"
/db_xref="SGD:S000004221"
/db_xref="GeneID:850933"
/translation="MEKALELDGEYPESLRDEFNIPTFKSMGLSSDDKPVTYLCGNSL
GLMPKSTRNSINAELDAWSDCAVESHFKHPEEARGKVPWVSIDLPILPLLAPIVGAQE
NEVAVMNSLTANLNSLLITFYKPTEKRFKILFEKGSFPSDYYAFYNQCKIHGISEPEN
VFIQIEPREGETYIRTQDILDTIEVNQDELALVCLSGVQYYTGQYFDIGRITSFAHQF
PDILVGWDLAHAVGNVPLQLHDWGVDFACWCSYKYLNAGPGGIGGLFVHSKHTKPDPA
KESLPRLAGWWGNDPAKRFQMLEVFEPIPGALGFRQSNPSVIDTVALRSSLELFAKFN
GINEVRKRSLLLTNYMTELLEASKYYKHPLRIEKLPCFFTILTPTSTDEEHGAQLSLY
FDSDTGKEDIMPKVFQYLHDHGVIGDARRPNVIRLAPAPLYNTFSDVYIAVNALNEAM
DKL"
gene complement(607425..609524)
/gene="EST1"
/locus_tag="YLR233C"
/db_xref="GeneID:850934"
mRNA complement(607425..609524)
/gene="EST1"
/locus_tag="YLR233C"
/product="Est1p"
/transcript_id="NM_001182120.1"
/db_xref="GI:296146769"
/db_xref="GeneID:850934"
CDS complement(607425..609524)
/gene="EST1"
/locus_tag="YLR233C"
/EC_number="2.7.7.-"
/note="TLC1 RNA-associated factor involved in telomere
length regulation as recruitment subunit of telomerase;
has G-quadruplex promoting activity that is required for
telomere elongation; possible role in activating
telomere-bound Est2p-TLC1-RNA"
/codon_start=1
/product="Est1p"
/protein_id="NP_013334.1"
/db_xref="GI:6323262"
/db_xref="SGD:S000004223"
/db_xref="GeneID:850934"
/translation="MDNEEVNEECMRLFFKNARAHLDKHLTSRLTCDENAYITFRCFL
DGIHRKSTRFLEELLLKQENMYHNNNYERINDSVIPLVLKLLWLQIHEPTLQWFEHWF
HDIMRLSNRRKFRVFRIFQKKMIQFFKITHRYYYDIIEHLCAKYDMNSVISNALFAKL
NLMQYTDGLSTHEKIILNTSNPLTFSIVISLQRCVINLGSTHFYKTLLNKPSNKPKSV
EGFEKSIRYLNIASLYLPAVGDTYFQRAKIYLITGKFSLYFFELVRGALVRIPSKCAL
NNLKDFILTPDFPERRRLMKKLAILVSKDLKGEKSFFEGQIVLQFLSIVEHTLVPQSW
NASRASNCWLLKEHLQMAALKYHSGNINVILENLAATMGSFDLMFTTRKSKEQKNKLK
YADLSERQVFFLDLSFDFIANIIDVVIKPSWQKNMEDFRYLAIIRLLMCWIKSYRSIL
QYTHRHRKFCTSFALLLNDLINSPLNCSGNIYSHRPKRSYLFREDIIFREFSCINFAL
TDFNDDYVYDSPDMINNIIGCPTLTKVLSPKEECVLRIRSIIFSGMKFLEKNDTGVIW
NASKYKFDLISPNIKIKRQIALSEISSKINVKTQQERVVSSRKVEAKRDEQQRKRAGK
IAVTELEKQFANVRRTKKLSPLPEKDGVSSELVKHAASRGRKTITGPLSSDFLSYPDE
AIDADEDITVQVPDTPT"
gene 609783..611753
/gene="TOP3"
/locus_tag="YLR234W"
/gene_synonym="EDR1"
/db_xref="GeneID:850935"
mRNA 609783..611753
/gene="TOP3"
/locus_tag="YLR234W"
/gene_synonym="EDR1"
/product="DNA topoisomerase 3"
/transcript_id="NM_001182121.1"
/db_xref="GI:296146770"
/db_xref="GeneID:850935"
CDS 609783..611753
/gene="TOP3"
/locus_tag="YLR234W"
/gene_synonym="EDR1"
/EC_number="5.99.1.2"
/note="DNA Topoisomerase III, conserved protein that
functions in a complex with Sgs1p and Rmi1p to relax
single-stranded negatively-supercoiled DNA preferentially,
involved in telomere stability and regulation of mitotic
recombination"
/codon_start=1
/product="DNA topoisomerase 3"
/protein_id="NP_013335.1"
/db_xref="GI:6323263"
/db_xref="SGD:S000004224"
/db_xref="GeneID:850935"
/translation="MKVLCVAEKNSIAKAVSQILGGGRSTSRDSGYMYVKNYDFMFSG
FPFARNGANCEVTMTSVAGHLTGIDFSHDSHGWGKCAIQELFDAPLNEIMNNNQKKIA
SNIKREARNADYLMIWTDCDREGEYIGWEIWQEAKRGNRLIQNDQVYRAVFSHLERQH
ILNAARNPSRLDMKSVHAVGTRIEIDLRAGVTFTRLLTETLRNKLRNQATMTKDGAKH
RGGNKNDSQVVSYGTCQFPTLGFVVDRFERIRNFVPEEFWYIQLVVENKDNGGTTTFQ
WDRGHLFDRLSVLTFYETCIETAGNVAQVVDLKSKPTTKYRPLPLTTVELQKNCARYL
RLNAKQSLDAAEKLYQKGFISYPRTETDTFPHAMDLKSLVEKQAQLDQLAAGGRTAWA
SYAASLLQPENTSNNNKFKFPRSGSHDDKAHPPIHPIVSLGPEANVSPVERRVYEYVA
RHFLACCSEDAKGQSMTLVLDWAVERFSASGLVVLERNFLDVYPWARWETTKQLPRLE
MNALVDIAKAEMKAGTTAPPKPMTESELILLMDTNGIGTDATIAEHIDKIQVRNYVRS
EKVGKETYLQPTTLGVSLVHGFEAIGLEDSFAKPFQRREMEQDLKKICEGHASKTDVV
KDIVEKYRKYWHKTNACKNTLLQVYDRVKASM"
gene 612367..614163
/gene="THI7"
/locus_tag="YLR237W"
/gene_synonym="THI10"
/db_xref="GeneID:850938"
mRNA 612367..614163
/gene="THI7"
/locus_tag="YLR237W"
/gene_synonym="THI10"
/product="Thi7p"
/transcript_id="NM_001182124.1"
/db_xref="GI:296146771"
/db_xref="GeneID:850938"
CDS 612367..614163
/gene="THI7"
/locus_tag="YLR237W"
/gene_synonym="THI10"
/note="Plasma membrane transporter responsible for the
uptake of thiamine, member of the major facilitator
superfamily of transporters; mutation of human ortholog
causes thiamine-responsive megaloblastic anemia"
/codon_start=1
/product="Thi7p"
/protein_id="NP_013338.1"
/db_xref="GI:6323266"
/db_xref="SGD:S000004227"
/db_xref="GeneID:850938"
/translation="MSFGSKVSRALRFLEIPVKDRASVSFLKNPDLQPIKSANQTWGF
WSNFAYWGVMSFSVGTWMSASSALGVGLSYPETIGTFIVGDVLTIIFTLANSCPGYDW
KVGFTLAQRFVFGIYGSAFGIIIRILMSIVNYGSNAWVGGLCINMILDSWSHHYLHLP
NTLSSKVAMTTKELIGFIIFHVLTAFCYLMKPYHMNYILIWSCVATFFSMLGMVIYLA
KQAHGVGELFTSTKSTATGSTKAWAWVYMISYWFGSVSPGSTNQSDYSRFGSSNWAIW
AGTICALLIPTTLIPVFGVIGASTCDKLYGEQYWMPMDIFNHWLTTNYSAGARAGAFF
CGLSFVLSQMSYTISNCGFASGMDLAGLLPKYVDIKRGALFAACVSWACLPWNFYNSS
STFLTVMSSFGVVMTPIISVMICDNFLIRKRQYSITNAFILKGEYYFTKGVNWRAIVA
WVCGMTPGLPGIAWEVNNDYFHNTGIVNFFYGDSFFSFLISFFVYWGLCLLFPFKITV
KHDDKDYYGAFTDEEARKKGMVPYSEISEEEIRAYTLGEGYTTGHEYRPEGSDDEIPE
LVKTSSENTNEFEIVHHKNNEKQSSTASEKAA"
gene 614755..616191
/gene="FAR10"
/locus_tag="YLR238W"
/db_xref="GeneID:850939"
mRNA 614755..616191
/gene="FAR10"
/locus_tag="YLR238W"
/product="Far10p"
/transcript_id="NM_001182125.1"
/db_xref="GI:296146772"
/db_xref="GeneID:850939"
CDS 614755..616191
/gene="FAR10"
/locus_tag="YLR238W"
/note="Protein involved in recovery from cell cycle arrest
in response to pheromone, in a Far1p-independent pathway;
interacts with Far3p, Far7p, Far8p, Far9p, and Far11p;
potential Cdc28p substrate"
/codon_start=1
/product="Far10p"
/protein_id="NP_013339.1"
/db_xref="GI:6323267"
/db_xref="SGD:S000004228"
/db_xref="GeneID:850939"
/translation="MTGPGPEINKEEHPSSPGKKQITYNSIPKNANLIDGSTNSSKRP
IEKYDKRIADPTKSYFPHSISRTPRRKYTYILVLTSLNGTFESKHVVIPFKPDGLKLG
RPVANSNSSSSSSLRGGKRVDSHTFSQVRSDNGNFDSRVLSRNHALLSCDPLTGKVYI
RDLKSSNGTFINGQRIGSNDVEIKVGDVIDLGTDIDTKIEHRKISATVEELFVQPLLE
SPIFENEDSDDCHTITEKEEAAAITSHIYGDSNNLELEEVILGSDTEILSGIFINNCI
GTSPTLSNIIKTLAMEIPFSKCDNFKLQSMENFLINYTTHLEYTNKLLVEKNDQQLVK
LQNGLRRKLSGKYEKIIEQNRNQVKQLERDHMFFKKSFEVKKRRNNEKQKSMEREIED
LKTRLEVERYKNSQMMKKNKQKEQELSTASKKKTTEHDTRGVPGMNPKGTDKFSIKNT
LCNHFTLLTFGTISIGIIAIVFKILSPN"
gene complement(616332..617318)
/gene="LIP2"
/locus_tag="YLR239C"
/db_xref="GeneID:850940"
mRNA complement(616332..617318)
/gene="LIP2"
/locus_tag="YLR239C"
/product="lipoyl(octanoyl) transferase LIP2"
/transcript_id="NM_001182126.1"
/db_xref="GI:296146773"
/db_xref="GeneID:850940"
CDS complement(616332..617318)
/gene="LIP2"
/locus_tag="YLR239C"
/EC_number="2.3.1.181"
/note="Lipoyl ligase, involved in the modification of
mitochondrial enzymes by the attachment of lipoic acid
groups"
/codon_start=1
/product="lipoyl(octanoyl) transferase LIP2"
/protein_id="NP_013340.1"
/db_xref="GI:6323268"
/db_xref="SGD:S000004229"
/db_xref="GeneID:850940"
/translation="MSRCIRQSVCTNFNVCRRQCFSTYASALKEMTHPIKPSAQTLRH
LQFTQRIPFQKGLEIQETLVRANLDIKDIQSKIERKLIQLDEEYKGTATINDNEKRIL
DKVMAMKPNPIILTFEFEPTYTGGKRIKKTMTPDQIAAYESFIPETQKDNPRPKFVQV
ERGGQVTFHGPGQIVIYIILDLKTFQSFPAKCLVSCIEQATIRTLKNTKMCDDTDKPL
NLDAMTTKDTGVWVENGKKKVASVGIHVRRSITSHGVAINVNTDLSYMNSFEMCGLKN
TLTTSIMEQRPDAVVNVQSVAISFVKEMTKLLGIKTLERMQIDDVNILKKNP"
gene 617533..620160
/gene="VPS34"
/locus_tag="YLR240W"
/gene_synonym="END12; PEP15; STT8; VPL7; VPS7; VPT29"
/db_xref="GeneID:850941"
mRNA 617533..620160
/gene="VPS34"
/locus_tag="YLR240W"
/gene_synonym="END12; PEP15; STT8; VPL7; VPS7; VPT29"
/product="phosphatidylinositol 3-kinase VPS34"
/transcript_id="NM_001182127.1"
/db_xref="GI:296146774"
/db_xref="GeneID:850941"
CDS 617533..620160
/gene="VPS34"
/locus_tag="YLR240W"
/gene_synonym="END12; PEP15; STT8; VPL7; VPS7; VPT29"
/EC_number="2.7.1.137"
/note="Phosphatidylinositol 3-kinase responsible for the
synthesis of phosphatidylinositol 3-phosphate; forms
membrane-associated signal transduction complex with
Vps15p to regulate protein sorting; activated by the
GTP-bound form of Gpa1p"
/codon_start=1
/product="phosphatidylinositol 3-kinase VPS34"
/protein_id="NP_013341.1"
/db_xref="GI:6323269"
/db_xref="SGD:S000004230"
/db_xref="GeneID:850941"
/translation="MSLNNITFCVSQDLDVPLKVKIKSLEGHKPLLKPSQKILNPELM
LIGSNVFPSSDLIVSLQVFDKERNRNLTLPIYTPYIPFRNSRTWDYWLTLPIRIKQLT
FSSHLRIILWEYNGSKQIPFFNLETSIFNLKDCTLKRGFESLKFRYDVIDHCEVVTDN
KDQENLNKYFQGEFTRLPWLDEITISKLRKQRENRTWPQGTFVLNLEFPMLELPVVFI
EREIMNTQMNIPTLKNNPGLSTDLREPNRNDPQIKISLGDKYHSTLKFYDPDQPNNDP
IEEKYRRLERASKNANLDKQVKPDIKKRDYLNKIINYPPGTKLTAHEKGSIWKYRYYL
MNNKKALTKLLQSTNLREESERVEVLELMDSWAEIDIDDALELLGSTFKNLSVRSYAV
NRLKKASDKELELYLLQLVEAVCFENLSTFSDKSNSEFTIVDAVSSQKLSGDSMLLST
SHANQKLLKSISSESETSGTESLPIVISPLAEFLIRRALVNPRLGSFFYWYLKSESED
KPYLDQILSSFWSRLDKKSRNILNDQVRLINVLRECCETIKRLKDTTAKKMELLVHLL
ETKVRPLVKVRPIALPLDPDVLICDVCPETSKVFKSSLSPLKITFKTTLNQPYHLMFK
VGDDLRQDQLVVQIISLMNELLKNENVDLKLTPYKILATGPQEGAIEFIPNDTLASIL
SKYHGILGYLKLHYPDENATLGVQGWVLDNFVKSCAGYCVITYILGVGDRHLDNLLVT
PDGHFFHADFGYILGQDPKPFPPLMKLPPQIIEAFGGAESSNYDKFRSYCFVAYSILR
RNAGLILNLFELMKTSNIPDIRIDPNGAILRVRERFNLNMSEEDATVHFQNLINDSVN
ALLPIVIDHLHNLAQYWRT"
gene 620473..622821
/locus_tag="YLR241W"
/db_xref="GeneID:850942"
mRNA 620473..622821
/locus_tag="YLR241W"
/product="hypothetical protein"
/transcript_id="NM_001182128.1"
/db_xref="GI:296146775"
/db_xref="GeneID:850942"
CDS 620473..622821
/locus_tag="YLR241W"
/note="hypothetical protein, may be involved in
detoxification"
/codon_start=1
/product="hypothetical protein"
/protein_id="NP_013342.1"
/db_xref="GI:6323270"
/db_xref="SGD:S000004231"
/db_xref="GeneID:850942"
/translation="MTSYIERLKSAASYLDTVPDEHHDFRKPTAKVVTTQLTIATSLG
IFALLSFSILLKKWPRLYASRRYKDDGNLRLPSWNQSSLFGWLTVLYKIRDEQILEYA
GLDAYVFLSFFKMCIKLLSIFCFFSVCVISPVRYHFTGKIDDGNDDDDSESSLIHLVK
RIVEGSGDGDNHSAPERTNVYLWMYVLFTYFFTFIAIKMAVAETKHVVSTRQAYLGKQ
NTITDRTIRLSGIPIELRDSEALKTRIEQLKIGTVSSITICREWGPLNKLFHCRKKIL
KNLELKYSECPRELRTRQPYSENYHLLGNEQSGAVTHGENVPSSNNNDEDTILYSQIS
LGERPKMKIGYRGIFGKEVDAIEYLEQQLKFIDAEIIEARKQHYSATPTAFVTMDSVA
NAQMAAQAVLDPRVHYFITRLAPAPHDIKWDHVCLSRKDRLTKVYSTTVFIGLSSLFL
VIPVSYLATLLNLKTLSKFWPSVGQLLKDHQWAANIVTGLLPTYLFTLLNFGIPYFYE
YLTSYQGLVSYSEEEISLVSKNFFYIFVNLFLVFTLAGTASNYWAYLSDTTKIAYQLA
TSVKEFSLFYVDLIILQGIGMFPFKLLLVGSLIGFPLVKIKAKTPRQRNELYNPPIFN
FGLQLPQPILILIITLIYSVMSTKILTSGLAYFIIGFYVYKYQLIFATDHLPHSTGKV
WPLIFRRIIVGLLLFQLTMTGTLAGFEGGWVLSSCLFPLPVVTLCFLYDFEKNYLPLS
KYIALSSIREYERDNSTVNSANEEESYAYPYAVSELEGPMLD"
gene complement(622918..623883)
/gene="ARV1"
/locus_tag="YLR242C"
/db_xref="GeneID:850943"
mRNA complement(622918..623883)
/gene="ARV1"
/locus_tag="YLR242C"
/product="Arv1p"
/transcript_id="NM_001182129.1"
/db_xref="GI:296146776"
/db_xref="GeneID:850943"
CDS complement(622918..623883)
/gene="ARV1"
/locus_tag="YLR242C"
/note="Protein functioning in transport of
glycosylphosphatidylinositol intermediates into ER lumen;
required for normal intracellular sterol distribution;
human ARV1 required for normal cholesterol and bile acid
homeostasis; similar to Nup120p"
/codon_start=1
/product="Arv1p"
/protein_id="NP_013343.1"
/db_xref="GI:6323271"
/db_xref="SGD:S000004232"
/db_xref="GeneID:850943"
/translation="MICITCMRPVDSLYTVYSNDHIQLTDCPYCQETVDKYVEIDNVL
LFIDLLLLKAGAYRHLVFNALELHLSKYPKRKALNDCQCLRDYTQALLFNVKNWFCKY
DRLNRLWLLLLSFEIYLTWVTEESKYIYYLNRNNNDGKLIMLSKKLPESFKWDSAIMR
NTITSKVFTWSPPIQYLYFASYCILDVSLFHTFTQYFILKKLHWKHYSVSSKDVISYT
ILLSYGAKIFPILMLIWPYDTLISMSIIKWVANLYIIESLKIVTNLSYWNIIKIFISV
SLLRYFMVKPILIVFVAKFNFSVIKNLIHQEFILLLQKSGTYLLL"
rep_origin 623198..623861
/note="ARS1219;
Replication origin; identified in multiple array studies,
confirmed by plasmid-based recombinational ARS assay"
/db_xref="SGD:S000130183"
gene 624203..625021
/gene="GPN3"
/locus_tag="YLR243W"
/db_xref="GeneID:850944"
mRNA 624203..625021
/gene="GPN3"
/locus_tag="YLR243W"
/product="Gpn3p"
/transcript_id="NM_001182130.1"
/db_xref="GI:296146777"
/db_xref="GeneID:850944"
CDS 624203..625021
/gene="GPN3"
/locus_tag="YLR243W"
/note="Putative GTPase with a role in biogenesis of RNA
pol II and polIII; may be involved in assembly of RNA
polymerases II and III and in their transport into the
nucleus; contains a Gly-Pro-Asn motif in the G domain;
similar to Npa3p and Gpn2p"
/codon_start=1
/product="Gpn3p"
/protein_id="NP_013344.1"
/db_xref="GI:6323272"
/db_xref="SGD:S000004233"
/db_xref="GeneID:850944"
/translation="MSRVGVMVLGPAGAGKSTFCNSIISHMQTVGRRAHIVNLDPAAE
ATKYEFTIDIRDLISLDDVMEEMDLGPNGALIYCFEYLLKNLDWLDEEIGDFNDEYLI
FDCPGQIELYTHIPVLPNIVRHLTQQLNFNLCATYLLEAPFVIDSSKFFSGALSAMSA
MILLELPHINVLSKLDLIKGDINKKKLKRFLNPDAMLLMETEGMNQASNPKFLRLNQC
IANLVDDFGMVQFLPLESNNPDSIETILSYVDDITQWAEGQEQKEPNDQIDVEE"
gene complement(625168..626331)
/gene="MAP1"
/locus_tag="YLR244C"
/db_xref="GeneID:850945"
mRNA complement(625168..626331)
/gene="MAP1"
/locus_tag="YLR244C"
/product="Map1p"
/transcript_id="NM_001182131.1"
/db_xref="GI:296146778"
/db_xref="GeneID:850945"
CDS complement(625168..626331)
/gene="MAP1"
/locus_tag="YLR244C"
/EC_number="3.4.11.18"
/note="Methionine aminopeptidase, catalyzes the
cotranslational removal of N-terminal methionine from
nascent polypeptides; function is partially redundant with
that of Map2p"
/codon_start=1
/product="Map1p"
/protein_id="NP_013345.1"
/db_xref="GI:6323273"
/db_xref="SGD:S000004234"
/db_xref="GeneID:850945"
/translation="MSTATTTVTTSDQASHPTKIYCSGLQCGRETSSQMKCPVCLKQG
IVSIFCDTSCYENNYKAHKALHNAKDGLEGAYDPFPKFKYSGKVKASYPLTPRRYVPE
DIPKPDWAANGLPVSEQRNDRLNNIPIYKKDQIKKIRKACMLGREVLDIAAAHVRPGI
TTDELDEIVHNETIKRGAYPSPLNYYNFPKSLCTSVNEVICHGVPDKTVLKEGDIVNL
DVSLYYQGYHADLNETYYVGENISKEALNTTETSRECLKLAIKMCKPGTTFQELGDHI
EKHATENKCSVVRTYCGHGVGEFFHCSPNIPHYAKNRTPGVMKPGMVFTIEPMINEGT
WKDMTWPDDWTSTTQDGKLSAQFEHTLLVTEHGVEILTARNKKSPGGPRQRIK"
gene complement(626502..626930)
/gene="CDD1"
/locus_tag="YLR245C"
/db_xref="GeneID:850946"
mRNA complement(626502..626930)
/gene="CDD1"
/locus_tag="YLR245C"
/product="cytidine deaminase"
/transcript_id="NM_001182132.1"
/db_xref="GI:296146779"
/db_xref="GeneID:850946"
CDS complement(626502..626930)
/gene="CDD1"
/locus_tag="YLR245C"
/EC_number="3.5.4.5"
/note="Cytidine deaminase; catalyzes the modification of
cytidine to uridine in vitro but native RNA substrates
have not been identified, localizes to both the nucleus
and cytoplasm"
/codon_start=1
/product="cytidine deaminase"
/protein_id="NP_013346.1"
/db_xref="GI:6323274"
/db_xref="SGD:S000004235"
/db_xref="GeneID:850946"
/translation="MKVGGIEDRQLEALKRAALKACELSYSPYSHFRVGCSILTNNDV
IFTGANVENASYSNCICAERSAMIQVLMAGHRSGWKCMVICGDSEDQCVSPCGVCRQF
INEFVVKDFPIVMLNSTGSRSKVMTMGELLPMAFGPSHLN"
gene 627118..628197
/gene="ERF2"
/locus_tag="YLR246W"
/db_xref="GeneID:850947"
mRNA 627118..628197
/gene="ERF2"
/locus_tag="YLR246W"
/product="Erf2p"
/transcript_id="NM_001182133.1"
/db_xref="GI:296146780"
/db_xref="GeneID:850947"
CDS 627118..628197
/gene="ERF2"
/locus_tag="YLR246W"
/EC_number="2.3.1.-"
/note="Subunit of a palmitoyltransferase, composed of
Erf2p and Shr5p, that adds a palmitoyl lipid moiety to
heterolipidated substrates such as Ras1p and Ras2p through
a thioester linkage; mutants partially mislocalize Ras2p
to the vacuole"
/codon_start=1
/product="Erf2p"
/protein_id="NP_013347.1"
/db_xref="GI:6323275"
/db_xref="SGD:S000004236"
/db_xref="GeneID:850947"
/translation="MALVSRRSTRSESTSITKEEHTGEGSLTKLFFRWLVTLEGDQDI
NDGKGYISLPNVSNYIFFLGGRFRTVKGAKPLWLGVLLAIVCPMVLFSIFEAHKLWHT
QNGYKVLVIFFYYFWVITLASFIRTATSDPGVLPRNIHLSQLRNNYQIPQEYYNLITL
PTHSSISKDITIKYCPSCRIWRPPRSSHCSTCNVCVMVHDHHCIWVNNCIGKRNYRFF
LIFLLGAILSSVILLTNCAIHIARESGGPRDCPVAILLLCYAGLTLWYPAILFTYHIF
MAGNQQTTREFLKGIGSKKNPVFHRVVKEENIYNKGSFLKNMGHLMLEPRGPSFVSAR
KPHEAGDWRFMDLSPAHSFEKIQKI"
gene 628383..628497
/locus_tag="tL(CAA)L"
/db_xref="GeneID:850948"
tRNA join(628383..628420,628454..628497)
/locus_tag="tL(CAA)L"
/product="tRNA-Leu"
/note="Leucine tRNA (tRNA-Leu), predicted by tRNAscan-SE
analysis"
/db_xref="SGD:S000006643"
/db_xref="GeneID:850948"
gene complement(628684..633354)
/gene="IRC20"
/locus_tag="YLR247C"
/db_xref="GeneID:850949"
mRNA complement(628684..633354)
/gene="IRC20"
/locus_tag="YLR247C"
/product="Irc20p"
/transcript_id="NM_001182134.1"
/db_xref="GI:296146781"
/db_xref="GeneID:850949"
CDS complement(628684..633354)
/gene="IRC20"
/locus_tag="YLR247C"
/EC_number="3.6.1.-"
/note="Putative helicase; localizes to the mitochondrion
and the nucleus; YLR247C is not an essential gene; null
mutant displays increased levels of spontaneous Rad52p
foci"
/codon_start=1
/product="Irc20p"
/protein_id="NP_013348.1"
/db_xref="GI:6323276"
/db_xref="SGD:S000004237"
/db_xref="GeneID:850949"
/translation="MSAVGALLAREYNVTAEKCDFFLENGSFDSVIAALPALNQEQET
VTQKVSKNGKELINVASVNIEIPERISLSNNGRQLFKFIVDIEILPCENDNEATLVVS
SDSVSLFQIGFKMENNSKIAVDKQLPLILDICAHKNQERALRNQLENRKSLERKPSRK
RRKKNSNVNDPEKLLKSRIHELSLSYKDFECSPVVFRYNDSSLTWVLSFNLKLKFLNN
KFNRFSVEANQILDLTFSNRDENEFERYHKHSHIHSNFIQKQFISQILEYSKDRLSKI
KPFLPQSIPDLKVNLLPFQRESVEWMLIKEGHGNSLSDTPTVIDEVGLIDFMNEYYAY
GYELIARSPDEVGPSLLWNKLTGYILTTEDAAHLYNQYRKERLSGDYPVCAKGVLAEE
MGLGKTIEILSLILLNRRKLKDSEATFIDDENRTITKTKTTLIICPNAILKQWLEEIE
LHANSLKWYTYRGYNEIMKDCKTVDEAVQQLCQYDIIVTSYNIIATEVHHAEFNRSIR
SRRLKSPKYDYSSPLALMQFYRIILDEVQMLRSSSTYSAKCTSLLHRIHTWGVSGTPI
QNIYNFRMIMSYLKLHPFCDEVDFIRTLQEEIKLRNEAKDYTSNDFVCQLKGVRFSIK
DCMNIFYRYDLCIRHSKANVASQIHIPRQHNFIIPLEFAPIEWDNYLNLWNNFLELSG
YNSDGSGSPRVSNAFLNEWLSRLRYICCHALFPEILSTRQKRLHGHLSRISNIDDILI
SMRMDAFDSLIGYYRERFHLSIKQAQYELEISNTPAKALESFIKIRDDLMIHIRQKFN
VEDPFDKSLNLSEDEDEHMDERFGEKETSSGDESDREINGAKNHDNHNNDGMLSNHLK
KKGLRAMMNLLHDCYFFLGSVYYNLGTRKLEEADDKHRKEKTEEVVYSDVFPKNELEE
IEENRLLEQENYANAEILRKSILSSEARKVDMTIKMARTKFAPMTSNIPLRLINIEFD
HKNDYSSNLAVSRCFKSLSKLIEGLNEQTKNFNELLDELLIIIYEPVHRTEDDDSTNK
IIGNEEYSTSIDSQDKIFSLLGCLEIILQNRDNILTSESEVKIPKHLVPEGSIISKYQ
KQLLNSLRLISGTPLRTVFDELKNSRIVRRISSSNESESTIQNFEDYLLQYEVESKSL
FKYNKQVRESLKILGSIYNAKTEYYSQLQRISDSLVSLHSLSAPQLSHLIRTINKSLG
GTLDAKINNIESRLIYLKNLSRLKDTLNDNQILSCSICLGEVEIGAIIKCGHYFCKSC
ILTWLRAHSKCPICKGFCSISEVYNFKFKNSTEKREKEIQEPRREGADSSQDNSNENS
IISNMSEVEKLFGNKYEQFHQINEVHQIHIKESFGAKIDFVIKLISYLRLKSEQENAD
PPQVILYSQKTEYLKVIGKVLKLYHIEHLACLSNTANVGETINNFKRQPSVTCLLLNV
KTLGAGLNLINAKHIFLLDPILNNSDELQAMGRNNRIGQDEETFVWNFMIRNTVEENI
LRYKCILEERKRKEKSKKGDKYDEAQDETDNEESDDAKFEISVVDQEVSNEHLWNCFF
HGSD"
STS 633081..633487
/standard_name="D1S3698"
/db_xref="UniSTS:474276"
gene 634252..636084
/gene="RCK2"
/locus_tag="YLR248W"
/gene_synonym="CLK1; CMK3"
/db_xref="GeneID:850950"
mRNA 634252..636084
/gene="RCK2"
/locus_tag="YLR248W"
/gene_synonym="CLK1; CMK3"
/product="Rck2p"
/transcript_id="NM_001182135.1"
/db_xref="GI:296146782"
/db_xref="GeneID:850950"
CDS 634252..636084
/gene="RCK2"
/locus_tag="YLR248W"
/gene_synonym="CLK1; CMK3"
/EC_number="2.7.11.1"
/note="Protein kinase involved in the response to
oxidative and osmotic stress; identified as suppressor of
S. pombe cell cycle checkpoint mutations; similar to CaM
(calmodulin) kinases"
/codon_start=1
/product="Rck2p"
/protein_id="NP_013349.1"
/db_xref="GI:6323277"
/db_xref="SGD:S000004238"
/db_xref="GeneID:850950"
/translation="MLKIKALFSKKKPDQADLSQESKKPFKGKTRSSGTNNKDVSQIT
SSPKKSFQDKNIVQYPSVVADDHHMKSLTDELVTTIDSDSSPSDNITTENVETVTSVP
AIDVHESSEGQLSSDPLISDESLSEQSEIISDIQDDSTDDDNMEDEIPEKSFLEQKEL
IGYKLINKIGEGAFSKVFRAIPAKNSSNEFLTKNYKAVAIKVIKKADLSSINGDHRKK
DKGKDSTKTSSRDQVLKEVALHKTVSAGCSQIVAFIDFQETDSYYYIIQELLTGGEIF
GEIVRLTYFSEDLSRHVIKQLALAVKHMHSLGVVHRDIKPENLLFEPIEFTRSIKPKL
RKSDDPQTKADEGIFTPGVGGGGIGIVKLADFGLSKQIFSKNTKTPCGTVGYTAPEVV
KDEHYSMKVDMWGIGCVLYTMLCGFPPFYDEKIDTLTEKISRGEYTFLKPWWDEISAG
AKNAVAKLLELEPSKRYDIDQFLDDPWLNTFDCLPKEGESSQKKAGTSERRHPHKKQF
QLFQRDSSLLFSPAAVAMRDAFDIGNAVKRTEEDRMGTRGGLGSLAEDEELEDSYSGA
QGDEQLEQNMFQLTLDTSTILQRRKKVQENDVGPTIPISATIRE"
gene 636780..639914
/gene="YEF3"
/locus_tag="YLR249W"
/gene_synonym="TEF3"
/db_xref="GeneID:850951"
mRNA 636780..639914
/gene="YEF3"
/locus_tag="YLR249W"
/gene_synonym="TEF3"
/product="Yef3p"
/transcript_id="NM_001182136.1"
/db_xref="GI:296146783"
/db_xref="GeneID:850951"
CDS 636780..639914
/gene="YEF3"
/locus_tag="YLR249W"
/gene_synonym="TEF3"
/note="Gamma subunit of translational elongation factor
eEF1B, stimulates the binding of aminoacyl-tRNA (AA-tRNA)
to ribosomes by releasing eEF1A (Tef1p/Tef2p) from the
ribosomal complex; contains two ABC cassettes; binds and
hydrolyzes ATP"
/codon_start=1
/product="Yef3p"
/protein_id="NP_013350.1"
/db_xref="GI:6323278"
/db_xref="SGD:S000004239"
/db_xref="GeneID:850951"
/translation="MSDSQQSIKVLEELFQKLSVATADNRHEIASEVASFLNGNIIEH
DVPEHFFGELAKGIKDKKTAANAMQAVAHIANQSNLSPSVEPYIVQLVPAICTNAGNK
DKEIQSVASETLISIVNAVNPVAIKALLPHLTNAIVETNKWQEKIAILAAISAMVDAA
KDQVALRMPELIPVLSETMWDTKKEVKAAATAAMTKATETVDNKDIERFIPSLIQCIA
DPTEVPETVHLLGATTFVAEVTPATLSIMVPLLSRGLNERETGIKRKSAVIIDNMCKL
VEDPQVIAPFLGKLLPGLKSNFATIADPEAREVTLRALKTLRRVGNVGEDDAIPEVSH
AGDVSTTLQVVNELLKDETVAPRFKIVVEYIAAIGADLIDERIIDQQAWFTHITPYMT
IFLHEKKAKDILDEFRKRAVDNIPVGPNFDDEEDEGEDLCNCEFSLAYGAKILLNKTQ
LRLKRARRYGICGPNGCGKSTLMRAIANGQVDGFPTQEECRTVYVEHDIDGTHSDTSV
LDFVFESGVGTKEAIKDKLIEFGFTDEMIAMPISALSGGWKMKLALARAVLRNADILL
LDEPTNHLDTVNVAWLVNYLNTCGITSITISHDSVFLDNVCEYIINYEGLKLRKYKGN
FTEFVKKCPAAKAYEELSNTDLEFKFPEPGYLEGVKTKQKAIVKVTNMEFQYPGTSKP
QITDINFQCSLSSRIAVIGPNGAGKSTLINVLTGELLPTSGEVYTHENCRIAYIKQHA
FAHIESHLDKTPSEYIQWRFQTGEDRETMDRANRQINENDAEAMNKIFKIEGTPRRIA
GIHSRRKFKNTYEYECSFLLGENIGMKSERWVPMMSVDNAWIPRGELVESHSKMVAEV
DMKEALASGQFRPLTRKEIEEHCSMLGLDPEIVSHSRIRGLSGGQKVKLVLAAGTWQR
PHLIVLDEPTNYLDRDSLGALSKALKEFEGGVIIITHSAEFTKNLTEEVWAVKDGRMT
PSGHNWVSGQGAGPRIEKKEDEEDKFDAMGNKIAGGKKKKKLSSAELRKKKKERMKKK
KELGDAYVSSDEEF"
gene 640317..641021
/gene="SSP120"
/locus_tag="YLR250W"
/db_xref="GeneID:850952"
mRNA 640317..641021
/gene="SSP120"
/locus_tag="YLR250W"
/product="Ssp120p"
/transcript_id="NM_001182137.1"
/db_xref="GI:296146784"
/db_xref="GeneID:850952"
CDS 640317..641021
/gene="SSP120"
/locus_tag="YLR250W"
/note="hypothetical protein; green fluorescent protein
(GFP)-fusion protein localizes to the cytoplasm in a
punctate pattern"
/codon_start=1
/product="Ssp120p"
/protein_id="NP_013351.1"
/db_xref="GI:6323279"
/db_xref="SGD:S000004240"
/db_xref="GeneID:850952"
/translation="MRFLRGFVFSLAFTLYKVTATAEIGSEINVENEAPPDGLSWEEW
HMDHEHQLKDYTPETFFALHDIKKKGFLDENDILSLYGLNREEIVGAGDGMGQHDESE
KIDNEMAKRVVSLIMRLLDVDDNTKITKEEYLQFAKRGNKFPDLGVGVGHHSDFELEY
EIHHWNKFHKDKDPDVKVVHKEDIEHELLHHEHEIEHEEEIQRGASRATVITDDELES
RIELKNIPEKFKNGIF"
gene 641464..642057
/gene="SYM1"
/locus_tag="YLR251W"
/db_xref="GeneID:850953"
mRNA 641464..642057
/gene="SYM1"
/locus_tag="YLR251W"
/product="Sym1p"
/transcript_id="NM_001182138.1"
/db_xref="GI:296146785"
/db_xref="GeneID:850953"
CDS 641464..642057
/gene="SYM1"
/locus_tag="YLR251W"
/note="Protein required for ethanol metabolism; induced by
heat shock and localized to the inner mitochondrial
membrane; homologous to mammalian peroxisomal membrane
protein Mpv17"
/codon_start=1
/product="Sym1p"
/protein_id="NP_013352.1"
/db_xref="GI:6323280"
/db_xref="SGD:S000004241"
/db_xref="GeneID:850953"
/translation="MKLLHLYEASLKRRPKTTNAIMTGALFGIGDVSAQLLFPTSKVN
KGYDYKRTARAVIYGSLIFSFIGDKWYKILNNKIYMRNRPQYHWSNMVLRVAVDQLAF
APLGLPFYFTCMSIMEGRSFDVAKLKIKEQWWPTLLTNWAVWPLFQAINFSVVPLQHR
LLAVNVVAIFWNTYLSYKNSKVMEKDKVPVHYPPVVE"
gene 642627..644336
/locus_tag="YLR253W"
/db_xref="GeneID:850955"
mRNA 642627..644336
/locus_tag="YLR253W"
/product="hypothetical protein"
/transcript_id="NM_001182140.1"
/db_xref="GI:296146786"
/db_xref="GeneID:850955"
CDS 642627..644336
/locus_tag="YLR253W"
/note="hypothetical protein; the authentic, non-tagged
protein is detected in highly purified mitochondria in
high-throughput studies; transcription is periodic during
the metabolic cycle; YLR253W is not an essential gene"
/codon_start=1
/product="hypothetical protein"
/protein_id="NP_013354.1"
/db_xref="GI:6323282"
/db_xref="SGD:S000004243"
/db_xref="GeneID:850955"
/translation="MMTKAFFNKLPFEVFRRYVRTGKSIPQRSPRTRKSLLVGGTIAS
AVVLYNFNDTFHDSVKHTALTTKRIAVVTQATTRCFYHYKRALNKSYENKKEREVALN
KCHKMCALITLHALRSNGGIYIKLGQHIGAMTYLLPKEWTDTMIPLQDHCPESTYEEI
DELFKEDLGTSIEDMFLEFNKTPIGVASLAQVHVAKLKNSDGKGSSVAVKCQHPSLKE
FIPLDVMLTRTVFELLDVFFPDYPLTWLGDELQSSIYVELNFTKEAENAEKTRHYFSK
FKKQTALKIPKVIESHKRILIMEYVGGKRLDDLEYIDSHGISRSEVSSCLSHIFNNMI
FTPNVGIHCDPHGGNLAIRSVKPAKDNGYHNFEIVLFDHGLYRYPSTRTRRLYAKFWL
SLLFDKDQTKMKKYAKGFANITDEQFPLLAAAITGRSIDAALNYDISTSRTQEEMDVM
ANGILEGTLLSDLMSILSRIPRVVLLILKTNDLTRHLDECLQNPLGPERTFLIMTQYC
AKTVYDEKVERINSEYARWSIKWMWENLTNWIVYERRINQLYFYDFVLWWKKFIPKTW
LSS"
gene complement(644404..644973)
/gene="NDL1"
/locus_tag="YLR254C"
/db_xref="GeneID:850956"
mRNA complement(644404..644973)
/gene="NDL1"
/locus_tag="YLR254C"
/product="Ndl1p"
/transcript_id="NM_001182141.1"
/db_xref="GI:296146787"
/db_xref="GeneID:850956"
CDS complement(644404..644973)
/gene="NDL1"
/locus_tag="YLR254C"
/note="Homolog of nuclear distribution factor NudE, NUDEL;
interacts with Pac1p and regulates dynein targeting to
microtubule plus ends"
/codon_start=1
/product="Ndl1p"
/protein_id="NP_013355.1"
/db_xref="GI:6323283"
/db_xref="SGD:S000004244"
/db_xref="GeneID:850956"
/translation="MVPNLDLETAIQIISSLETQLSELEGATKEYENDLEQVISKLKS
DLLESQQQNKCNKKQITDLEIQVDELENENIQLRNKIETLQLESDRRLERNVLLEHEL
LDTKEALQKLRVSKEEATSGETRRNTRSLPSQNKKMKLFKDTIKVSTTSSTLYLQNMA
KTNNAARSHCNIPNTQITQSTVIATTSSV"
gene 646415..650923
/gene="HAP1"
/locus_tag="YLR256W"
/gene_synonym="CYP1"
/db_xref="GeneID:850958"
mRNA 646415..650923
/gene="HAP1"
/locus_tag="YLR256W"
/gene_synonym="CYP1"
/product="Hap1p"
/transcript_id="NM_001182143.1"
/db_xref="GI:296146788"
/db_xref="GeneID:850958"
CDS 646415..650923
/gene="HAP1"
/locus_tag="YLR256W"
/gene_synonym="CYP1"
/note="Zinc finger transcription factor involved in the
complex regulation of gene expression in response to
levels of heme and oxygen; the S288C sequence differs from
other strain backgrounds due to a Ty1 insertion in the
carboxy terminus"
/codon_start=1
/product="Hap1p"
/protein_id="NP_013357.1"
/db_xref="GI:6323285"
/db_xref="SGD:S000004246"
/db_xref="GeneID:850958"
/translation="MSNTPYNSSVPSIASMTQSSVSRSPNMHTATTPGANTSSNSPPL
HMSSDSSKIKRKRNRIPLSCTICRKRKVKCDKLRPHCQQCTKTGVAHLCHYMEQTWAE
EAEKELLKDNELKKLRERVKSLEKTLSKVHSSPSSNSLKSYNTPESSNLFMGSDEHTT
LVNANTGSASSASHMHQQQQQQQQQEQQQDFSRSANANANSSSLSISNKYDNDELDLT
KDFDLLHIKSNGTIHLGATHWLSIMKGDPYLKLLWGHIFAMREKLNEWYYQKNSYSKL
KSSKCPINHAQAPPSAAAAATRKCPVDHSAFSSGMVAPKEETPLPRKCPVDHTMFSSG
MIPPREDTSSQKRCPVDHTMYSAGMMPPKDETPSPFSTKAMIDHNKHTMNPPQSKCPV
DHRNYMKDYPSDMANSSSNPASRCPIDHSSMKNTAALPASTHNTIPHHQPQSGSHARS
HPAQSRKHDSYMTESEVLATLCEMLPPKRVIALFIEKFFKHLYPAIPILDEQNFKNHV
NQMLSLSSMNPTVNNFGMSMPSSSTLENQPITQINLPKLSDSCNLGILIIILRLTWLS
IPSNSCEVDLGEESGSFLVPNESSNMSASALTSMAKEESLLLKHETPVEALELCQKYL
IKFDELSSISNNNVNLTTVQFAIFYNFYMKSASNDLTTLTNTNNTGMANPGHDSESHQ
ILLSNITQMAFSCGLHRDPDNFPQLNATIPATSQDVSNNGSKKANPSTNPTLNNNMSA
ATTNSSSRSGSADSRSGSNPVNKKENQVSIERFKHTWRKIWYYIVSMDVNQSLSLGSP
RLLRNLRDFSDTKLPSASRIDYVRDIKELIIVKNFTLFFQIDLCIIAVLNHILNVSLA
RSVRKFELDSLINLLKNLTYGTENVNDVVSSLINKGLLPTSEGGSVDSNNDEIYGLPK
LPDILNHGQHNQNLYADGRNTSSSDIDKKLDLPHESTTRALFFSKHMTIRMLLYLLNY
ILFTHYEPMGSEDPGTNILAKEYAQEALNFAMDGYRNCMIFFNNIRNTNSLFDYMNVI
LSYPCLDIGHRSLQFIVCLILRAKCGPLTGMRESSIITNGTSSGFNSSVEDEDVKVKQ
ESSDELKKDDFMKDVNLDSGDSLAEILMSRMLLFQKLTKQLSKKYNYAIRMNKSTGFF
VSLLDTPSKKSDSKSGGSSFMLGNWKHPKVSNMSGFLAGDKDQLQKCPVYQDALGFVS
PTGANEGSAPMQGMSLQGSTARMGGTQLPPIRSYKPITYTSSNLRRMNETGEAEAKRR
RFNDGYIDNNSNNDIPRGISPKPSNGLSSVQPLLSSFSMNQLNGGTIPTVPSLTNITS
QMGALPSLDRITTNQINLPDPSRDEAFDNSIKQMTPMTSAFMNANTTIPSSTLNGNMN
MNGAGTANTDTSANGSALSTLTSPQGSDLASNSATQYKPDLEDFLMQNSNFNGLMINP
SSLVEVVGGYNDPNNLGRNDAVDFLPVDNVEIDGVGIKINYHLLTSIYVTSILSYTVL
EDDANDEK"
mobile_element 650824..656743
/note="YLRWTy1-3; Ty1 element, LTR retrotransposon of the
Copia (Pseudoviridae) group; contains co-transcribed genes
TYA Gag and TYB Pol, encoding proteins involved in
structure and function of virus-like particles, flanked by
two direct repeats"
/mobile_element_type="retrotransposon:YLRWTy1-3"
/db_xref="SGD:S000007099"
LTR 650824..651157
/note="Ty1 LTR"
/db_xref="SGD:S000007088"
gene 651117..652439
/locus_tag="YLR256W-A"
/db_xref="GeneID:850959"
mRNA <651117..>652439
/locus_tag="YLR256W-A"
/transcript_id="NM_001184409.1"
/db_xref="GI:296146789"
/db_xref="GeneID:850959"
CDS 651117..652439
/locus_tag="YLR256W-A"
/note="Retrotransposon TYA Gag gene co-transcribed with
TYB Pol; translated as TYA or TYA-TYB polyprotein; Gag is
a nucleocapsid protein that is the structural constituent
of virus-like particles (VLPs); similar to retroviral Gag"
/codon_start=1
/product="gag protein"
/protein_id="NP_058173.1"
/db_xref="GI:7839188"
/db_xref="SGD:S000007377"
/db_xref="GeneID:850959"
/translation="MESQQLSQHPHISHGSACASVTSKEVHTNQDPLDVSASKTEECE
KASTKANSQQTTTPASSAVPENPHHASPQPASVPPPQNGPYPQQCMMTQNQANPSGWS
FYGHPSMIPYTPYQMSPMYFPPGPQSQFPQYPSSVGTPLSTPSPESGNTFTDSSSADS
DMTSTKKYVRPPPMLTSPNDFPNWVKTYIKFLQNSNLGGIIPTVNGKPVRQITDDELT
FLYNTFQIFAPSQFLPTWVKDILSVDYTDIMKILSKSIEKMQSDTQEANDIVTLANLQ
YNGSTPADAFETKVTNIIDRLNNNGIHINNKVACQLIMRGLSGEYKFLRYTRHRHLNM
TVAELFLDIHAIYEEQQGSRNSKPNYRRNLSDEKNDSRSYTNTTKPKVIARNPQKTNN
SKSKTARAHNVSTSNNSPSTDNDSISKSTTEPIQLNNKHDLHLRPGTY"
LTR 656410..656743
/note="Ty1 LTR"
/db_xref="SGD:S000007089"
gene complement(656934..657006)
/locus_tag="tA(AGC)L"
/db_xref="GeneID:850960"
tRNA complement(656934..657006)
/locus_tag="tA(AGC)L"
/product="tRNA-Ala"
/note="Alanine tRNA (tRNA-Ala), predicted by tRNAscan-SE
analysis; one of 11 nuclear tRNA genes containing the
tDNA-anticodon AGC (converted to IGC in the mature tRNA),
decodes GCU and GCC codons into alanine, one of 16 nuclear
tRNAs for alanine"
/db_xref="SGD:S000006517"
/db_xref="GeneID:850960"
LTR 657022..657365
/note="Ty3 LTR"
/db_xref="SGD:S000007096"
LTR 657449..657767
/note="Ty1 LTR"
/db_xref="SGD:S000007090"
gene 658826..659791
/locus_tag="YLR257W"
/db_xref="GeneID:850961"
mRNA 658826..659791
/locus_tag="YLR257W"
/product="hypothetical protein"
/transcript_id="NM_001182144.1"
/db_xref="GI:296146790"
/db_xref="GeneID:850961"
CDS 658826..659791
/locus_tag="YLR257W"
/note="hypothetical protein; protein abundance increases
in response to DNA replication stress"
/codon_start=1
/product="hypothetical protein"
/protein_id="NP_013358.1"
/db_xref="GI:6323286"
/db_xref="SGD:S000004247"
/db_xref="GeneID:850961"
/translation="MVDARGSTPCLIGDSIRNVNDGNSLDFQYTNQFNEESEASRLLT
PQTSSNHALSKMQKDDDIRDRSYTSVAELNREGALLTDEVDLENVDASKVRSNRDDLE
AEEKRKKLLLLKKKQRNKSINSESFSSPSLRASKSNSLITSTDPVEDHISKYSSSGTP
ENITGEADDEDEDIIRNSYGQMIKNNSNRPHLAKGESYQSAEQEIDHTAPEKSEKRQE
RSGRSFDRQKSSAEFLRSLSRSISRGPTKNKTVSPSKGEDSRMYSTSNYSISLVDLEN
GPKIIPETLEEEQEDAEKEGVLMEDEGNEEYTKDLEEAANKAQPQ"
rep_origin 659824..660072
/note="ARS1220;
Autonomously Replicating Sequence"
/db_xref="SGD:S000118478"
gene 660716..662833
/gene="GSY2"
/locus_tag="YLR258W"
/db_xref="GeneID:850962"
mRNA 660716..662833
/gene="GSY2"
/locus_tag="YLR258W"
/product="glycogen (starch) synthase GSY2"
/transcript_id="NM_001182145.1"
/db_xref="GI:296146791"
/db_xref="GeneID:850962"
CDS 660716..662833
/gene="GSY2"
/locus_tag="YLR258W"
/EC_number="2.4.1.11"
/note="Glycogen synthase; expression induced by glucose
limitation, nitrogen starvation, heat shock, and
stationary phase; activity regulated by cAMP-dependent,
Snf1p and Pho85p kinases as well as by the Gac1p-Glc7p
phosphatase; GSY2 has a paralog, GSY1, that arose from the
whole genome duplication; relocalizes from cytoplasm to
plasma membrane upon DNA replication stress"
/codon_start=1
/product="glycogen (starch) synthase GSY2"
/protein_id="NP_013359.1"
/db_xref="GI:6323287"
/db_xref="SGD:S000004248"
/db_xref="GeneID:850962"
/translation="MSRDLQNHLLFETATEVANRVGGIYSVLKSKAPITVAQYKDHYH
LIGPLNKATYQNEVDILDWKKPEAFSDEMRPVQHALQTMESRGVHFVYGRWLIEGAPK
VILFDLDSVRGYSNEWKGDLWSLVGIPSPENDFETNDAILLGYTVAWFLGEVAHLDSQ
HAIVAHFHEWLAGVALPLCRKRRIDVVTIFTTHATLLGRYLCASGSFDFYNCLESVDV
DHEAGRFGIYHRYCIERAAAHSADVFTTVSQITAFEAEHLLKRKPDGILPNGLNVIKF
QAFHEFQNLHALKKEKINDFVRGHFHGCFDFDLDNTLYFFIAGRYEYKNKGADMFIEA
LARLNYRLKVSGSKKTVVAFIVMPAKNNSFTVEALKGQAEVRALENTVHEVTTSIGKR
IFDHAIRYPHNGLTTELPTDLGELLKSSDKVMLKRRILALRRPEGQLPPIVTHNMVDD
ANDLILNKIRQVQLFNSPSDRVKMIFHPEFLNANNPILGLDYDEFVRGCHLGVFPSYY
EPWGYTPAECTVMGVPSITTNVSGFGAYMEDLIETNQAKDYGIYIVDRRFKAPDESVE
QLVDYMEEFVKKTRRQRINQRNRTERLSDLLDWKRMGLEYVKARQLALRRGYPDQFRE
LVGEELNDSNMDALAGGKKLKVARPLSVPGSPRDLRSNSTVYMTPGDLGTLQEVNNAD
DYFSLGVNPAADDDDDGPYADDS"
gene complement(663284..665002)
/gene="HSP60"
/locus_tag="YLR259C"
/gene_synonym="CPN60; MIF4; MNA2"
/db_xref="GeneID:850963"
mRNA complement(663284..665002)
/gene="HSP60"
/locus_tag="YLR259C"
/gene_synonym="CPN60; MIF4; MNA2"
/product="Hsp60p"
/transcript_id="NM_001182146.1"
/db_xref="GI:296146792"
/db_xref="GeneID:850963"
CDS complement(663284..665002)
/gene="HSP60"
/locus_tag="YLR259C"
/gene_synonym="CPN60; MIF4; MNA2"
/note="Tetradecameric mitochondrial chaperonin required
for ATP-dependent folding of precursor polypeptides and
complex assembly; prevents aggregation and mediates
protein refolding after heat shock; role in mtDNA
transmission; phosphorylated"
/codon_start=1
/product="chaperone ATPase HSP60"
/protein_id="NP_013360.1"
/db_xref="GI:6323288"
/db_xref="SGD:S000004249"
/db_xref="GeneID:850963"
/translation="MLRSSVVRSRATLRPLLRRAYSSHKELKFGVEGRASLLKGVETL
AEAVAATLGPKGRNVLIEQPFGPPKITKDGVTVAKSIVLKDKFENMGAKLLQEVASKT
NEAAGDGTTSATVLGRAIFTESVKNVAAGCNPMDLRRGSQVAVEKVIEFLSANKKEIT
TSEEIAQVATISANGDSHVGKLLASAMEKVGKEGVITIREGRTLEDELEVTEGMRFDR
GFISPYFITDPKSSKVEFEKPLLLLSEKKISSIQDILPALEISNQSRRPLLIIAEDVD
GEALAACILNKLRGQVKVCAVKAPGFGDNRKNTIGDIAVLTGGTVFTEELDLKPEQCT
IENLGSCDSITVTKEDTVILNGSGPKEAIQERIEQIKGSIDITTTNSYEKEKLQERLA
KLSGGVAVIRVGGASEVEVGEKKDRYDDALNATRAAVEEGILPGGGTALVKASRVLDE
VVVDNFDQKLGVDIIRKAITRPAKQIIENAGEEGSVIIGKLIDEYGDDFAKGYDASKS
EYTDMLATGIIDPFKVVRSGLVDASGVASLLATTEVAIVDAPEPPAAAGAGGMPGGMP
GMPGMM"
gene 665844..667907
/gene="LCB5"
/locus_tag="YLR260W"
/db_xref="GeneID:850964"
mRNA 665844..667907
/gene="LCB5"
/locus_tag="YLR260W"
/product="sphinganine kinase LCB5"
/transcript_id="NM_001182147.1"
/db_xref="GI:296146793"
/db_xref="GeneID:850964"
CDS 665844..667907
/gene="LCB5"
/locus_tag="YLR260W"
/EC_number="2.7.1.91"
/note="Minor sphingoid long-chain base kinase, paralog of
Lcb4p responsible for few percent of the total activity,
possibly involved in synthesis of long-chain base
phosphates, which function as signaling molecules"
/codon_start=1
/product="sphinganine kinase LCB5"
/protein_id="NP_013361.1"
/db_xref="GI:6323289"
/db_xref="SGD:S000004250"
/db_xref="GeneID:850964"
/translation="MTLKPSKRRKGRSRHSRKKQITSAILTEEGIMIKAKPSSPYTYA
NRMADKRSRSSIDNISRTSFQSNISRTSFQSNSDNNSIFETASLISCVTCLSDTDTID
RSETSTTDTSKDDLSANPKLHYPSVNGQLPANTVIPYGRILDARYIEKEPLHYYDANS
SPSSPLSSSMSNISEKCDLDELESSQKKERKGNSLSRGSNSSSSLLTSRSPFTKLVEV
IFARPRRHDVVPKRVSLYIDYKPHSSSHLKEEDDLVEEILKRSYKNTRRNKSIFVIIN
PFGGKGKAKKLFMTKAKPLLLASRCSIEVVYTKYPGHAIEIAREMDIDKYDTIACASG
DGIPHEVINGLYQRPDHVKAFNNIAITEIPCGSGNAMSVSCHWTNNPSYSTLCLIKSI
ETRIDLMCCSQPSYAREHPKLSFLSQTYGLIAETDINTEFIRWMGPARFELGVAFNII
QKKKYPCEIYVKYAAKSKNELKNHYLEHKNKGSLEFQHITMNKDNEDCDNYNYENEYE
TENEDEDEDADADDEDSHLISRDLADSSADQIKEEDFKIKYPLDEGIPSDWERLDPNI
SNNLGIFYTGKMPYVAADTKFFPAALPSDGTMDMVITDARTSLTRMAPILLGLDKGSH
VLQPEVLHSKILAYKIIPKLGNGLFSVDGEKFPLEPLQVEIMPRLCKTLLRNGRYVDT
DFDSM"
gene complement(668244..668891)
/gene="YPT6"
/locus_tag="YLR262C"
/db_xref="GeneID:850966"
mRNA complement(668244..668891)
/gene="YPT6"
/locus_tag="YLR262C"
/product="Ypt6p"
/transcript_id="NM_001182149.1"
/db_xref="GI:296146794"
/db_xref="GeneID:850966"
CDS complement(668244..668891)
/gene="YPT6"
/locus_tag="YLR262C"
/note="Rab family GTPase, Ras-like GTP binding protein
involved in the secretory pathway, required for fusion of
endosome-derived vesicles with the late Golgi, maturation
of the vacuolar carboxypeptidase Y; has similarity to the
human GTPase, Rab6"
/codon_start=1
/product="Ypt6p"
/protein_id="NP_013363.1"
/db_xref="GI:6323291"
/db_xref="SGD:S000004252"
/db_xref="GeneID:850966"
/translation="MSRSGKSLTKYKIVFLGEQGVGKTSLITRFMYDTFDDHYQATIG
IDFLSKTMYLDDKTIRLQLWDTAGQERFRSLIPSYIRDSRVAIIVYDITKRKSFEYID
KWIEDVKNERGDENVILCIVGNKSDLSDERQISTEEGEKKAKLLGAKIFMETSTKAGY
NVKALFKKIAKSLPEFQNSESTPLDSENANSANQNKPGVIDISTAEEQEQSACQC"
gene complement(669468..669662)
/gene="TMA7"
/locus_tag="YLR262C-A"
/db_xref="GeneID:850967"
mRNA complement(669468..669662)
/gene="TMA7"
/locus_tag="YLR262C-A"
/product="Tma7p"
/transcript_id="NM_001184339.1"
/db_xref="GI:296146795"
/db_xref="GeneID:850967"
CDS complement(669468..669662)
/gene="TMA7"
/locus_tag="YLR262C-A"
/note="Protein of unknown that associates with ribosomes;
null mutant exhibits translation defects, altered
polyribosome profiles, and resistance to the translation
inhibitor anisomcyin; protein abundance increases in
response to DNA replication stress"
/codon_start=1
/product="Tma7p"
/protein_id="NP_013364.1"
/db_xref="GI:6323292"
/db_xref="SGD:S000007246"
/db_xref="GeneID:850967"
/translation="MSSRQGGKMKPLKQKKKQQQDLDPEDIAFKEKQKADAAAKKALM
ANMKSGKPLVGGGIKKSGKK"
gene 670340..672823
/gene="RED1"
/locus_tag="YLR263W"
/db_xref="GeneID:850968"
mRNA 670340..672823
/gene="RED1"
/locus_tag="YLR263W"
/product="Red1p"
/transcript_id="NM_001182150.1"
/db_xref="GI:296146796"
/db_xref="GeneID:850968"
CDS 670340..672823
/gene="RED1"
/locus_tag="YLR263W"
/note="Protein component of the synaptonemal complex axial
elements, involved in chromosome segregation during the
first meiotic division; critical for coupling checkpoint
signaling to SC formation; interacts with Hop1p, Mec3p and
Ddc1p"
/codon_start=1
/product="Red1p"
/protein_id="NP_013365.1"
/db_xref="GI:6323293"
/db_xref="SGD:S000004253"
/db_xref="GeneID:850968"
/translation="MEGLKKKIFGVCLKNDLAQTRNETKGIHYGLMTLETSKQLQEFL
HLLVIKREVIQNFELLFHIINVAVKITDSNLPSDDIWHFILKLRFSSEINIDEDSKVL
NYLLETGIAMENPVSWKCLAVISSILSSVPQSKKIITNLIETEHAKKIGQLFDNIQDL
QQGNFLVEILSNCFKKSASNSKKVEKIPQLWQSRSKNKFFFENEFYPFSSKNGSLQTC
QFLCNNFMSTLSFTGILRQVSYSGSETLKNLRIFKKKDDENSYFIQCIYNKIYLWLDE
KAPLEFERKKIRITKNLKNKIQIKLRQPFHECVRTTADKTALLFNKTKGFQLEFEDEK
LGETFFHNVNNIPKISEVQNFLVLDYIEEEPENEGEEEEQIGRADEQKEDEEEESLDE
LSTPMVYPIKSSIPHNHNEKVQLVTPDRSVSIRSDEWDLKSNTEDEEGNVLADLKISS
TKETKRQTDYVHIDSEDQSPVVSAQMRKMRRESTKTLEILRQEFKDKDVQNKEDQSEQ
IQNPFVNTSSLVVGKSCLVNPKEKPNIDQTVVGITELKSNSSIKKRDINILDTIFGQP
PSKKQKQFHKKEKKKQQKKLTNFKPIIDVPSQDKRNLRSNAPTKPKSIKVSKLRTDKK
VTGEKSSPETAAEKVDDQTVRSNDEQAMSRATKEKCFPDVNEGKEITKDDAKVSLESK
KNNETFVDSSVVEKHTPPDKDCNNCNITDILESTTVIDLQSPHGLSAPGQNTFTNKLQ
EQIYSSINHFSNELVRKISIINQELNKKILKELSEKYQKLFSELQDNFQNDTNEMLKF
MGEIKDMMNLPEDQLVHAIRTRKFDNNKR"
gene 673131..673334
/gene="RPS28B"
/locus_tag="YLR264W"
/gene_synonym="RPS33B"
/db_xref="GeneID:850969"
mRNA 673131..673334
/gene="RPS28B"
/locus_tag="YLR264W"
/gene_synonym="RPS33B"
/product="ribosomal 40S subunit protein S28B"
/transcript_id="NM_001182151.1"
/db_xref="GI:296146797"
/db_xref="GeneID:850969"
CDS 673131..673334
/gene="RPS28B"
/locus_tag="YLR264W"
/gene_synonym="RPS33B"
/note="Protein component of the small (40S) ribosomal
subunit; homologous to mammalian ribosomal protein S28, no
bacterial homolog; RPS28B has a paralog, RPS28A, that
arose from the whole genome duplication"
/codon_start=1
/product="ribosomal 40S subunit protein S28B"
/protein_id="NP_013366.1"
/db_xref="GI:6323294"
/db_xref="SGD:S000004254"
/db_xref="GeneID:850969"
/translation="MDSKTPVTLAKVIKVLGRTGSRGGVTQVRVEFLEDTSRTIVRNV
KGPVRENDILVLMESEREARRLR"
gene complement(673828..673944)
/locus_tag="YLR264C-A"
/db_xref="GeneID:1466417"
mRNA complement(673828..673944)
/locus_tag="YLR264C-A"
/product="hypothetical protein"
/transcript_id="NM_001184638.1"
/db_xref="GI:296146798"
/db_xref="GeneID:1466417"
CDS complement(673828..673944)
/locus_tag="YLR264C-A"
/codon_start=1
/product="hypothetical protein"
/protein_id="NP_878129.1"
/db_xref="GI:33438841"
/db_xref="SGD:S000028808"
/db_xref="GeneID:1466417"
/translation="MNVIFKLYLTIDAPKKKKVTVRDFLSIRYSMPYRLASN"
gene complement(674427..675455)
/gene="NEJ1"
/locus_tag="YLR265C"
/gene_synonym="LIF2"
/db_xref="GeneID:850970"
mRNA complement(674427..675455)
/gene="NEJ1"
/locus_tag="YLR265C"
/gene_synonym="LIF2"
/product="Nej1p"
/transcript_id="NM_001182152.1"
/db_xref="GI:296146799"
/db_xref="GeneID:850970"
CDS complement(674427..675455)
/gene="NEJ1"
/locus_tag="YLR265C"
/gene_synonym="LIF2"
/note="Protein involved in regulation of nonhomologous end
joining; interacts with DNA ligase IV components Dnl4p and
Lif1p; repressed by MAT heterozygosity; regulates cellular
distribution of Lif1p"
/codon_start=1
/product="Nej1p"
/protein_id="NP_013367.1"
/db_xref="GI:6323295"
/db_xref="SGD:S000004255"
/db_xref="GeneID:850970"
/translation="MDSELKGQQLSDAEWCVKKINGEGNCLLLFLPMSSPTTIVMIVL
VSLERLVPYVFKLSQTQLSQQCQSQGFTDSISLNLIKLKLMDILQAPQEINQIGLVDS
NLVFSFDVSADITVSINSVPSHVTKDMFYMILQSLCMLLLKLVNLSTQYHYVQRDILN
EKQKCLDFLLISLRDLDGGSKVISQWAPENSKNYESLQQCTDDDIIKKLLHKGKFQHQ
EFLADSLKTLLSLRNKFQDVSRFEESGELNKKERVRFPAVNHFYNDDFELQADPTNEA
RPNSRGKIKPKTDFKPKSRESSTSSQLRLENFSESEATPEKTKSSSSLVEEYPQKKRK
FGKVRIKN"
gene complement(675619..677724)
/gene="PDR8"
/locus_tag="YLR266C"
/db_xref="GeneID:850971"
mRNA complement(675619..677724)
/gene="PDR8"
/locus_tag="YLR266C"
/product="Pdr8p"
/transcript_id="NM_001182153.1"
/db_xref="GI:296146800"
/db_xref="GeneID:850971"
CDS complement(675619..677724)
/gene="PDR8"
/locus_tag="YLR266C"
/note="Transcription factor; targets include ATP-binding
cassette (ABC) transporters, major facilitator superfamily
transporters, and other genes involved in the pleiotropic
drug resistance (PDR) phenomenon; PDR8 has a paralog,
YRR1, that arose from the whole genome duplication"
/codon_start=1
/product="Pdr8p"
/protein_id="NP_013368.1"
/db_xref="GI:6323296"
/db_xref="SGD:S000004256"
/db_xref="GeneID:850971"
/translation="MDGSHFPMKSTTGEPVSSGKKGKRRKVIKSCAFCRKRKLKCSQA
RPMCQQCVIRKLPQCVYTEEFNYPLSNTELFEQVPNVALVQKIENLQTLLKENDNNNA
KPVYCRSSENPLRSLRTSVLGDNGSRYVFGPTSWKTLSLFEQNKFQTEFQNLWKVLKP
LPECTKSQLNENDVVADLPSFPQMESCIKSFFAGPLFGILHIFNQDDILSLLDRLFIR
DTTDKNLVILLDLQGNAKDKYNLGIVLQILCLGYYNQDIPSSVSHFLHTLSAASLSSS
SSNFVEKLQFFLLSYISVMINCTDGVWDATQGVDLINELCQGCISLGLNDIDKWYLNE
SEETKQNLRCIWFWALFLDVSTSYDIGNPPSISDDLLDLSIFTAQNFQSPSIDFRRVK
LMHDFLDVSRFTTREIHKREMNEKLTTFSLRLIEFIQSNFSPIEHYTNSVYYSDIDPF
DILILSRSLSIVASIYNIEMIIAQQSRIIDKNRMVQFLLISISVCVNTMVFHFKEPIN
DQENVLTEGLKLSIILINPLLIRIVSQVYSLAFNRLIFREKAFLFLIDLDTGKKIQFI
KYEEENFDELLTGFDVRTDKFLSFSGTIIRFYEIIDSIFAVNERNKRLLKAVSNFYQL
TSTLAFERVSRVLFDKASQARIETEKIWLKKGINMEHFSDLMIEDFINDVWKTFKEIS
KDLWSIDKKKFYKQYHFDL"
gene 678212..679924
/gene="BOP2"
/locus_tag="YLR267W"
/db_xref="GeneID:850972"
mRNA 678212..679924
/gene="BOP2"
/locus_tag="YLR267W"
/product="Bop2p"
/transcript_id="NM_001182154.1"
/db_xref="GI:296146801"
/db_xref="GeneID:850972"
CDS 678212..679924
/gene="BOP2"
/locus_tag="YLR267W"
/codon_start=1
/product="Bop2p"
/protein_id="NP_013369.1"
/db_xref="GI:6323297"
/db_xref="SGD:S000004257"
/db_xref="GeneID:850972"
/translation="MVAALTYLPTELIQRIFEFTVVETDSQYWLYNLVALIDFSVSSR
GGGSITEDFLTNYVRKNLMVLDLTCEATQDSILRAEYGFLKRLLPYIDMDAQYIRVVD
LETNADKAQNLKAEKLIVIFDEFSDLKLIETFFPLANSNSNIIEFVFCVRNIKSSFYS
PLEKLHIANIVADIDINTLYLDFVDSNIYSDQNFFGIFDPDIFQLINKNYRNFFSKTN
EKGKKRPPICKKICFPFVETLNLDYMALDSFFNSILHKLTTKIKTFERNNEFDVDKNL
NLNSTTTVAALIIKSILQQFFNNFHISFPNLVTLNFIKMSTYPNNNEITQCCNFIDLS
SYVLNKCLSENISINFLFQLHSLKNWSMPKIKEFTGHKFKYDETTFSGSPERYIKSLR
GNIKILQEMAINETNDGTCYFRVKLIPEGVEKTQIINWIPFTSSFSDDTFKQRHHLKR
PMICLKNNSLRSLTVKIIRIEKCSSIRIQGFYLPNLQELFINNTLCDTTQHQKQASND
MSCIEFTSWNELPQCKKLGFAQLEDDSNYVLNISNLQDHLPNLDLRESFPTFFDIRQK
FVVV"
gene 680200..680844
/gene="SEC22"
/locus_tag="YLR268W"
/gene_synonym="SLY2; TSL26"
/db_xref="GeneID:850973"
mRNA 680200..680844
/gene="SEC22"
/locus_tag="YLR268W"
/gene_synonym="SLY2; TSL26"
/product="Sec22p"
/transcript_id="NM_001182155.1"
/db_xref="GI:296146802"
/db_xref="GeneID:850973"
CDS 680200..680844
/gene="SEC22"
/locus_tag="YLR268W"
/gene_synonym="SLY2; TSL26"
/note="R-SNARE protein; assembles into SNARE complex with
Bet1p, Bos1p and Sed5p; cycles between the ER and Golgi
complex; involved in anterograde and retrograde transport
between the ER and Golgi; synaptobrevin homolog"
/codon_start=1
/product="Sec22p"
/protein_id="NP_013370.1"
/db_xref="GI:6323298"
/db_xref="SGD:S000004258"
/db_xref="GeneID:850973"
/translation="MIKSTLIYREDGLPLCTSVDNENDPSLFEQKQKVKIVVSRLTPQ
SATEATLESGSFEIHYLKKSMVYYFVICESGYPRNLAFSYLNDIAQEFEHSFANEYPK
PTVRPYQFVNFDNFLQMTKKSYSDKKVQDNLDQLNQELVGVKQIMSKNIEDLLYRGDS
LDKMSDMSSSLKETSKRYRKSAQKINFDLLISQYAPIVIVAFFFVFLFWWIFLK"
gene 681186..682238
/gene="DCS1"
/locus_tag="YLR270W"
/db_xref="GeneID:850974"
mRNA 681186..682238
/gene="DCS1"
/locus_tag="YLR270W"
/product="Dcs1p"
/transcript_id="NM_001182157.1"
/db_xref="GI:296146803"
/db_xref="GeneID:850974"
CDS 681186..682238
/gene="DCS1"
/locus_tag="YLR270W"
/EC_number="3.-.-.-"
/note="Non-essential hydrolase involved in mRNA decapping;
activates Xrn1p; may function in a feedback mechanism to
regulate deadenylation, contains pyrophosphatase activity
and a HIT (histidine triad) motif; interacts with neutral
trehalase Nth1p; required for growth on glycerol medium;
protein abundance increases in response to DNA replication
stress"
/codon_start=1
/product="Dcs1p"
/protein_id="NP_013372.1"
/db_xref="GI:6323299"
/db_xref="SGD:S000004260"
/db_xref="GeneID:850974"
/translation="MSQLPTDFASLIKRFQFVSVLDSNPQTKVMSLLGTIDNKDAIIT
AEKTHFLFDETVRRPSQDGRSTPVLYNCENEYSCINGIQELKEITSNDIYYWGLSVIK
QDMESNPTAKLNLIWPATPIHIKKYEQQNFHLVRETPEMYKRIVQPYIEEMCNNGRLK
WVNNILYEGAESERVVYKDFSEENKDDGFLILPDMKWDGMNLDSLYLVAIVYRTDIKT
IRDLRYSDRQWLINLNNKIRSIVPGCYNYAVHPDELRILVHYQPSYYHFHIHIVNIKH
PGLGNSIAAGKAILLEDIIEMLNYLGPEGYMNKTITYAIGENHDLWKRGLEEELTKQL
ERDGIPKIPKIVNGFK"
gene 682737..683561
/locus_tag="YLR271W"
/db_xref="GeneID:850976"
mRNA 682737..683561
/locus_tag="YLR271W"
/product="hypothetical protein"
/transcript_id="NM_001182158.1"
/db_xref="GI:296146804"
/db_xref="GeneID:850976"
CDS 682737..683561
/locus_tag="YLR271W"
/note="hypothetical protein; green fluorescent protein
(GFP)-fusion protein localizes to the cytoplasm and the
nucleus and is induced in response to the DNA-damaging
agent MMS"
/codon_start=1
/product="hypothetical protein"
/protein_id="NP_013373.1"
/db_xref="GI:6323301"
/db_xref="SGD:S000004261"
/db_xref="GeneID:850976"
/translation="MEESKTKRKEDRIDLKNTPPQKKSKRDSTNDETARTSLRSIMPR
GYKMMENMGYKEGETLGSNESALKEPIKVEINTKRRGIRAEKPDPSTMNDMQMSEQRF
IKRESEMKNNKRLKKIWYRIQKVAFEMMGDSDLYNPGEDPRDFNVLWRSYVMQLNEEV
AKNDLNNHSNNDNEDKNNMIPMVNESLEASPAIKGEKFGRPSTLIDCDTSIIGSRITK
DTELAELEELSIEKRITKLNIFLRSEKYYCFFCGIKYKDEGDLYEHCPGVNEDDHK"
gene complement(683672..687202)
/gene="YCS4"
/locus_tag="YLR272C"
/gene_synonym="LOC7"
/db_xref="GeneID:850977"
mRNA complement(683672..687202)
/gene="YCS4"
/locus_tag="YLR272C"
/gene_synonym="LOC7"
/product="Ycs4p"
/transcript_id="NM_001182159.1"
/db_xref="GI:296146805"
/db_xref="GeneID:850977"
CDS complement(683672..687202)
/gene="YCS4"
/locus_tag="YLR272C"
/gene_synonym="LOC7"
/note="Subunit of the condensin complex; required for
establishment and maintenance of chromosome condensation,
chromosome segregation, chromatin binding of condensin,
tRNA gene clustering at the nucleolus, and silencing at
the mating type locus; required for replication slow zone
(RSZ) breakage following Mec1p inactivation"
/codon_start=1
/product="Ycs4p"
/protein_id="NP_013374.1"
/db_xref="GI:6323302"
/db_xref="SGD:S000004262"
/db_xref="GeneID:850977"
/translation="MSGFSLSEYLTKFQTTDRESYPRLQDPSRELNVIIDQLAVSPEQ
IDASPDSLEALIDLCHDFPHLTPKLQTQLSYLISSSLSNLSKDIKANLSSNVNFTEIG
GLIPQWKRHLEEYGYLIQVLLTFLQDELHKVSSQSTNLNRSAKNSKNDSANVELFKRD
CNQMENLLESITKLLEINLSKIFQTTPEKDLFIGLFTRPLFVLLEIEPVTKVSSLKMF
IQRILAMCVKNHGQSSSIQSSLMTNLTYFLHLSVFNAELLKLLNDEYNYPQLTEDILK
EISTRVFNAKDTTGPKAISNFLIKLSELSPGIMLRQMNLVITLLNNSSITLRCSVVEA
CGNIVAELAQDPQTMEHYKQQIAVLIELLEERFQDSNPYVRTKAIQGCSKICDLSSKF
NKSKAKFTSLAVRSLQDRSSLVRRNSVKLLSKLLLKHPFKAIHGSQLRLSEWEEYLKG
SESQLNSTLKKVESQETLNDTIERSLIEEEVEQDEGQCRTELEGSFNKSAELSRIENE
VENINATNTSVLMKLKLMIVYYKDAISFIKEIHKSIELISNLLFSKNRNEVLESMDFL
VLADAFDIELSEFGIKKMLHLVWMKGTNDEGTSISVHLIECYKQLFLTAPDSCNMQEK
AAHIAKNLINLSIGASIADLASLEQLLGMMYEQKLIDQHVINILWAIYNSASKASMQK
EQNVNNRDSEKGFSKEQIHGSIIILGMLSLADNEIALKGLESLLNIGLGAVGLKDLTL
CRYSCLALERMVPKRSTIITKAINQELEDVAVKKLYAIIINYTKDNEYYPMCEQALSA
LFTISSKPDILATDLIREKTMMTFGKPEEEDSILSLEQSSRVVSLSQLLFIVGQVAIK
TLVYLEKCEAEFKKRKIEAETRNGKVKNQGADVTNTTQDNGGDKELEMIGGTNEDDFT
DAIQFVKENELLFGEKSILGKFCPIVEEIVSNSSRFSDPMLQRTATLCLEKLMCLSSK
YCEKSLPLLITVMEKSPDPTIRSNAVLGLGDMAVCFNNLVDENTDYLYRRLHDENLMV
QRTCLMTVTFLILAGQVKVKGQLGEMAKCLDNPDQGISDMCRLFFTELASKDNAIYNG
FIDIFSNLSSDDLLGKESFKKIIKFLLTFIDKERHQKQLNEKLVGRLRKCETQKQWDD
IAFVLNNLPYKNEDVTALLEQGFKVVSAKE"
gene complement(687859..687932)
/locus_tag="tV(AAC)L"
/db_xref="GeneID:850978"
tRNA complement(687859..687932)
/locus_tag="tV(AAC)L"
/product="tRNA-Val"
/note="Valine tRNA (tRNA-Val), predicted by tRNAscan-SE
analysis"
/db_xref="SGD:S000006762"
/db_xref="GeneID:850978"
LTR complement(688119..688368)
/note="Ty1 LTR"
/db_xref="SGD:S000007071"
LTR 688369..688664
/note="Ty1 LTR"
/db_xref="SGD:S000007091"
gene complement(689083..691029)
/gene="PIG1"
/locus_tag="YLR273C"
/db_xref="GeneID:850979"
mRNA complement(689083..691029)
/gene="PIG1"
/locus_tag="YLR273C"
/product="Pig1p"
/transcript_id="NM_001182160.1"
/db_xref="GI:296146806"
/db_xref="GeneID:850979"
CDS complement(689083..691029)
/gene="PIG1"
/locus_tag="YLR273C"
/note="Putative targeting subunit for the type-1 protein
phosphatase Glc7p that tethers it to the Gsy2p glycogen
synthase"
/codon_start=1
/product="Pig1p"
/protein_id="NP_013375.1"
/db_xref="GI:6323303"
/db_xref="SGD:S000004263"
/db_xref="GeneID:850979"
/translation="MPYSHGKKLKPSLKLAKTISTSSFVSSTTSNSFSPLEDSTSASS
STSSSSSGKSVRFAAHLYTVKKFNTKLAPISISEKAASNLTRNLHNNAIPLTFPFIGG
EDHRYSLDILDYSDLEYDNKDVEYDNESDVEDNAMLMHDRSMFIEKEILCFGEEETFD
MADWKLVSNNLNPFKSDYKVDVTGLEDKIFKYLNGQNIKVHSLELSDPVSYEDICSNN
FGNCQIWGLIFVNNLNFEKKIEIKFTLNNWADIHYINAHYNKSVTPHVDEFKFIIDIS
ALKLNLISKNLIYTNFFERKTTCLLNLQFCCRYDVNGFEYRSFYDNNDYKNYEITISL
SAINLNRAVSNSSIFNSNLGPSKMGASNAEVTMSKNNENSKKPLRKFIKDTDYYNDSP
LKHKFYQSFETKAACKTEPVSQTFKAETIDCEIEPFNYFFEPPDSQTNEDMSDSSYDL
SLQDFNYWEFSNHGLGKALADSDILQFKNYPKPEPFSRPPIIDDTFTLNTDDRTLGSK
TQKLEDNLAKEWKSAKTRTTLNETPLHDDEHRTSFTYTTWNNSTDTLMKRKEERPVES
ASCSQLSIATIKAEEDLLYQDYINSGRESSSPEISPLNTTTSLPFFPGDNMSDSSGEY
EERTSLSPNKIHIFRDYFYKSPSP"
gene 691555..693882
/gene="MCM5"
/locus_tag="YLR274W"
/gene_synonym="BOB1; CDC46"
/db_xref="GeneID:850980"
mRNA 691555..693882
/gene="MCM5"
/locus_tag="YLR274W"
/gene_synonym="BOB1; CDC46"
/product="Mcm5p"
/transcript_id="NM_001182161.1"
/db_xref="GI:296146807"
/db_xref="GeneID:850980"
CDS 691555..693882
/gene="MCM5"
/locus_tag="YLR274W"
/gene_synonym="BOB1; CDC46"
/note="Component of the hexameric MCM complex, which is
important for priming origins of DNA replication in G1 and
becomes an active ATP-dependent helicase that promotes DNA
melting and elongation when activated by Cdc7p-Dbf4p in
S-phase"
/codon_start=1
/product="Mcm5p"
/protein_id="NP_013376.1"
/db_xref="GI:6323304"
/db_xref="SGD:S000004264"
/db_xref="GeneID:850980"
/translation="MSFDRPEIYSAPVLQGESPNDDDNTEIIKSFKNFILEFRLDSQF
IYRDQLRNNILVKNYSLTVNMEHLIGYNEDIYKKLSDEPSDIIPLFETAITQVAKRIS
ILSRAQSANNNDKDPENTSMDTDSLLLNSLPTFQLILNSNANQIPLRDLDSEHVSKIV
RLSGIIISTSVLSSRATYLSIMCRNCRHTTSITINNFNSITGNTVSLPRSCLSTIESE
SSMANESNIGDESTKKNCGPDPYIIIHESSKFIDQQFLKLQEIPELVPVGEMPRNLTM
TCDRYLTNKVIPGTRVTIVGIYSIYNSKNGAGSGRSGGGNGGSGVAIRTPYIKILGIQ
SDVETSSIWNSVTMFTEEEEEEFLQLSRNPKLYEILTNSIAPSIFGNEDIKKAIVCLL
MGGSKKILPDGMRLRGDINVLLLGDPGTAKSQLLKFVEKVSPIAVYTSGKGSSAAGLT
ASVQRDPMTREFYLEGGAMVLADGGVVCIDEFDKMRDEDRVAIHEAMEQQTISIAKAG
ITTVLNSRTSVLAAANPIYGRYDDLKSPGDNIDFQTTILSRFDMIFIVKDDHNEERDI
SIANHVINIHTGNANAMQNQQEENGSEISIEKMKRYITYCRLKCAPRLSPQAAEKLSS
NFVTIRKQLLINELESTERSSIPITIRQLEAIIRITESLAKLELSPIAQERHVDEAIR
LFQASTMDAASQDPIGGLNQASGTSLSEIRRFEQELKRRLPIGWSTSYQTLRREFVDT
HRFSQLALDKALYALEKHETIQLRHQGQNIYRSGV"
gene 694378..694800
/gene="SMD2"
/locus_tag="YLR275W"
/db_xref="GeneID:850981"
mRNA join(694378..694382,694473..694800)
/gene="SMD2"
/locus_tag="YLR275W"
/product="Smd2p"
/transcript_id="NM_001182162.1"
/db_xref="GI:296146808"
/db_xref="GeneID:850981"
CDS join(694378..694382,694473..694800)
/gene="SMD2"
/locus_tag="YLR275W"
/note="Core Sm protein Sm D2; part of heteroheptameric
complex (with Smb1p, Smd1p, Smd3p, Sme1p, Smx3p, and
Smx2p) that is part of the spliceosomal U1, U2, U4, and U5
snRNPs; homolog of human Sm D2"
/codon_start=1
/product="Smd2p"
/protein_id="NP_013377.1"
/db_xref="GI:6323305"
/db_xref="SGD:S000004265"
/db_xref="GeneID:850981"
/translation="MSSQIIDRPKHELSRAELEELEEFEFKHGPMSLINDAMVTRTPV
IISLRNNHKIIARVKAFDRHCNMVLENVKELWTEKKGKNVINRERFISKLFLRGDSVI
VVLKTPVE"
gene complement(695046..696830)
/gene="DBP9"
/locus_tag="YLR276C"
/db_xref="GeneID:850982"
mRNA complement(695046..696830)
/gene="DBP9"
/locus_tag="YLR276C"
/product="Dbp9p"
/transcript_id="NM_001182163.1"
/db_xref="GI:296146809"
/db_xref="GeneID:850982"
CDS complement(695046..696830)
/gene="DBP9"
/locus_tag="YLR276C"
/EC_number="3.6.1.-"
/note="DEAD-box protein required for 27S rRNA processing;
exhibits DNA, RNA and DNA/RNA helicase activities; ATPase
activity shows preference for DNA over RNA; DNA helicase
activity abolished by mutation in RNA-binding domain"
/codon_start=1
/product="Dbp9p"
/protein_id="NP_013378.1"
/db_xref="GI:6323306"
/db_xref="SGD:S000004266"
/db_xref="GeneID:850982"
/translation="MSYEKKSVEGAYIDDSTTFEAFHLDSRLLQAIKNIGFQYPTLIQ
SHAIPLALQQKRDIIAKAATGSGKTLAYLIPVIETILEYKKTIDNGEENGTLGIILVP
TRELAQQVYNVLEKLVLYCSKDIRTLNISSDMSDSVLSTLLMDQPEIIVGTPGKLLDL
LQTKINSISLNELKFLVVDEVDLVLTFGYQDDLNKIGEYLPLKKNLQTFLMSATLNDD
IQALKQKFCRSPAILKFNDEEINKNQNKLLQYYVKVSEFDKFLLCYVIFKLNLIKGKT
LIFVNNIDRGYRLKLVMEQFGIKSCILNSELPVNSRQHIVDQFNKNVYQLLIATDDTE
YIKEEDDEIEEGHNTENQEEKSLEGEPENDKKPSKKKKVQVKKDKEYGVSRGVDFKNV
ACVLNFDLPTTAKSYVHRVGRTARGGKTGTAISFVVPLKEFGKHKPSMLQTAKKDERI
LSRIIKQQSKLGLELQPYKFDQKQVEAFRYRMEDGFRAVTQVAIREARVKELKQELLA
SEKLKRHFEENPKELQSLRHDKELHPARVQQHLKRVPDYLLPESARGNGTKVKFVPFH
NAKKRHSHKKGRVSKPKNGKVDPLKNFK"
gene complement(697156..699495)
/gene="YSH1"
/locus_tag="YLR277C"
/gene_synonym="BRR5"
/db_xref="GeneID:850983"
mRNA complement(697156..699495)
/gene="YSH1"
/locus_tag="YLR277C"
/gene_synonym="BRR5"
/product="Ysh1p"
/transcript_id="NM_001182164.1"
/db_xref="GI:296146810"
/db_xref="GeneID:850983"
CDS complement(697156..699495)
/gene="YSH1"
/locus_tag="YLR277C"
/gene_synonym="BRR5"
/EC_number="3.1.27.-"
/note="Putative endoribonuclease; subunit of the mRNA
cleavage and polyadenylation specificity complex; required
for 3' processing, splicing, and transcriptional
termination of mRNAs and snoRNAs; protein abundance
increases in response to DNA replication stress"
/codon_start=1
/product="Ysh1p"
/protein_id="NP_013379.1"
/db_xref="GI:6323307"
/db_xref="SGD:S000004267"
/db_xref="GeneID:850983"
/translation="MERTNTTTFKFFSLGGSNEVGRSCHILQYKGKTVMLDAGIHPAY
QGLASLPFYDEFDLSKVDILLISHFHLDHAASLPYVMQRTNFQGRVFMTHPTKAIYRW
LLRDFVRVTSIGSSSSSMGTKDEGLFSDEDLVDSFDKIETVDYHSTVDVNGIKFTAFH
AGHVLGAAMFQIEIAGLRVLFTGDYSREVDRHLNSAEVPPLSSNVLIVESTFGTATHE
PRLNRERKLTQLIHSTVMRGGRVLLPVFALGRAQEIMLILDEYWSQHADELGGGQVPI
FYASNLAKKCMSVFQTYVNMMNDDIRKKFRDSQTNPFIFKNISYLRNLEDFQDFGPSV
MLASPGMLQSGLSRDLLERWCPEDKNLVLITGYSIEGTMAKFIMLEPDTIPSINNPEI
TIPRRCQVEEISFAAHVDFQENLEFIEKISAPNIILVHGEANPMGRLKSALLSNFASL
KGTDNEVHVFNPRNCVEVDLEFQGVKVAKAVGNIVNEIYKEENVEIKEEIAAKIEPIK
EENEDNLDSQAEKGLVDEEEHKDIVVSGILVSDDKNFELDFLSLSDLREHHPDLSTTI
LRERQSVRVNCKKELIYWHILQMFGEAEVLQDDDRVTNQEPKVKEESKDNLTNTGKLI
LQIMGDIKLTIVNTLAVVEWTQDLMNDTVADSIIAILMNVDSAPASVKLSSHSCDDHD
HNNVQSNAQGKIDEVERVKQISRLFKEQFGDCFTLFLNKDEYASNKEETITGVVTIGK
STAKIDFNNMKILECNSNPLKGRVESLLNIGGNLVTPLC"
gene complement(699999..704024)
/locus_tag="YLR278C"
/db_xref="GeneID:850984"
mRNA complement(699999..704024)
/locus_tag="YLR278C"
/product="hypothetical protein"
/transcript_id="NM_001182165.1"
/db_xref="GI:296146811"
/db_xref="GeneID:850984"
CDS complement(699999..704024)
/locus_tag="YLR278C"
/note="Zinc-cluster protein; GFP-fusion protein localizes
to the nucleus; mutant shows moderate growth defect on
caffeine; has a prion-domain like fragment that increases
frequency of [URE3]; YLR278C is not an essential gene"
/codon_start=1
/product="hypothetical protein"
/protein_id="NP_013380.1"
/db_xref="GI:6323308"
/db_xref="SGD:S000004268"
/db_xref="GeneID:850984"
/translation="MGRPRKNVSQEKIQQLKRELELAGNRTDVLLQDKKGRSRSCLLC
RRRKQRCDHKLPSCTACLKAGIKCVQPSKYSSSTSNSNTNNNTPTAGTVPPTPHPVIK
RELQDSSIGAGAGAATSLNDMTIIKPISTSNSNVDAGDANEFRKTIKSVTTNSNPNLM
RQDKDQYTIFLEKKLKSLETLLDLSPGCNQYNYELSQYKKVSHLFSNNTSDYSRPNSS
NMVILPLPSPSNKPLENTNNNGSNVNAATNDTSASTNNINNNNAICQSASLLNDPLET
LDFTKCIFAKYNLKKEFLMYDPIFELNEKLSRSFLDTFFTRLQFKYPILDEQEIYTFY
DHYLHNKILIPPSSPATSSAAPPSNSHSYSEIEFHFLSGRMWLVFSISAYLLMTTGKY
KGFPPHRYFSTAIRHITKCGLHLNYVQQIELLTLLVLYIIRTDRDSLILYDIIKDVMG
ISKKKLHLNQWYPNDPFANKKLRLFWCVYLLERMICVAVGKPYTIKESEINLPLFNND
SFYTKGVHAAAPSTNDHGVQFINQSLKLRRIESQFVETLQLLKNDSRSVKQSIDQLPL
VRKFFEDLEVWRKSYSTLDVKNFENETLKLYYYRSVRLLIQPYLEFFAPEDRLFRECQ
AAAGQICQLYKIFHQKTLNGHSTPAVHTVFVAGVTLIYCMWLARNFDDQRRKKLGDAS
KHTRPLISASLFSTMDDLRACSVCLYVMTERSNFARTFRDTFDQLMNATVGNLIERCG
PDSSELIFMASSVAKRTEPKNINDEANKAISSGDTLHDSNSANAANLSNSNDKNISHN
GGMPPAVARIFGKGQAEEHAGFVENSQVDLAEQEKFKKKQGVLEKTSVPKSLAHLLTK
MDDRSRISNSSMSYTTSSSSSSSSSSSSSTLSFPSSQEKNLKINVNNDNNGMTISSVN
REHNNNHNNNNDNNNNNNNNNNNSNNNNNVNNNDNESNSRSTTNNSCNNGNNSQYVRN
NNVTMENDVERPIQDQYIVKKPTNQTEFDWQVFQQQAFLQQQLAQHNLQAYLSSLNTD
TMTNRSPSKSSSISTASSHSDPIPIAMTQSPTPYPQTSNMLPQQHVSRPLPQQQREQP
QQHITSPQRFSESNFTNQLNNGMINSNPLQSAIFSNHTSENKQLRDVEESNFSTSPLR
ADYGNNIISSIPASFTSNSIPVSVKQARNGSSSGDILFSNGAHDMINNISTWTNNSVL
DALNSKSILQTIFPQSQEPSSLSMDKQQQQHQQQNMCSENNVTANNFQQTQNDPSYNR
NLFMMSNQEGVQYNLDETEKNGPKTQVEANTSANLHFDNVIPTVTNADIRKKRSNWDN
MMTSGPVEDFWTINDDYGFLT"
gene complement(704493..704960)
/locus_tag="YLR281C"
/db_xref="GeneID:850987"
mRNA complement(704493..704960)
/locus_tag="YLR281C"
/product="hypothetical protein"
/transcript_id="NM_001182168.1"
/db_xref="GI:296146812"
/db_xref="GeneID:850987"
CDS complement(704493..704960)
/locus_tag="YLR281C"
/note="hypothetical protein; green fluorescent protein
(GFP)-fusion protein localizes to mitochondria; YLR281C is
not an essential gene"
/codon_start=1
/product="hypothetical protein"
/protein_id="NP_013383.1"
/db_xref="GI:6323311"
/db_xref="SGD:S000004271"
/db_xref="GeneID:850987"
/translation="MMRGASKRSISSAAVLLIKKNKLPPRPKFTPEMEAQCTEKFLHG
GRGPGGQKINKCNSKVQLRHEPTGIVVECQETRSREQNRKLARLKLARELAASYDTMP
SREEALLQWHRQQKRSQRRRSVAKYEQREEAARVEKEEREARDREMVRELFRR"
gene 705186..706130
/locus_tag="YLR283W"
/db_xref="GeneID:850988"
mRNA 705186..706130
/locus_tag="YLR283W"
/product="hypothetical protein"
/transcript_id="NM_001182170.1"
/db_xref="GI:296146813"
/db_xref="GeneID:850988"
CDS 705186..706130
/locus_tag="YLR283W"
/note="hypothetical protein; green fluorescent protein
(GFP)-fusion protein localizes to mitochondria; YLR283W is
not an essential gene"
/codon_start=1
/product="hypothetical protein"
/protein_id="NP_013385.1"
/db_xref="GI:6323312"
/db_xref="SGD:S000004273"
/db_xref="GeneID:850988"
/translation="MMRLIRTLPLRCFKTRIRRQGSLLCLRCFSSYSKPLLQKSMSLK
NIQLSDLSSSPLSKNKEKQEKPEKENEGKHSIGLLDRFSEDFITQGNGLKPTTSQNQL
DTIKFYQMLRERGNFSDEQCKIIIALLLQLLNDQFYSCYNDLFLRDMELNKQSHLFSS
LETELKFAIQNSRDTQLNEHHLQLLKLKRELNSIHDELNEIIIDLLQKDAKLEFNNQK
LENTLLYRQLNLKLNDCSNKIQTKILGDIRSHIENLRWQTTRSGLLVILVLVCSIMIG
VSASKKERPGLQEPEEPEILAPKEDIDTTFPQDQHDID"
gene complement(706198..707040)
/gene="ECI1"
/locus_tag="YLR284C"
/db_xref="GeneID:850990"
mRNA complement(706198..707040)
/gene="ECI1"
/locus_tag="YLR284C"
/product="edodecenoyl-CoA isomerase"
/transcript_id="NM_001182171.1"
/db_xref="GI:296146814"
/db_xref="GeneID:850990"
CDS complement(706198..707040)
/gene="ECI1"
/locus_tag="YLR284C"
/EC_number="5.3.3.8"
/note="Peroxisomal delta3,delta2-enoyl-CoA isomerase,
hexameric protein that converts 3-hexenoyl-CoA to
trans-2-hexenoyl-CoA, essential for the beta-oxidation of
unsaturated fatty acids, oleate-induced"
/codon_start=1
/product="dodecenoyl-CoA isomerase"
/protein_id="NP_013386.1"
/db_xref="GI:6323314"
/db_xref="SGD:S000004274"
/db_xref="GeneID:850990"
/translation="MSQEIRQNEKISYRIEGPFFIIHLMNPDNLNALEGEDYIYLGEL
LELADRNRDVYFTIIQSSGRFFSSGADFKGIAKAQGDDTNKYPSETSKWVSNFVARNV
YVTDAFIKHSKVLICCLNGPAIGLSAALVALCDIVYSINDKVYLLYPFANLGLITEGG
TTVSLPLKFGTNTTYECLMFNKPFKYDIMCENGFISKNFNMPSSNAEAFNAKVLEELR
EKVKGLYLPSCLGMKKLLKSNHIDAFNKANSVEVNESLKYWVDGEPLKRFRQLGSKQR
KHRL"
gene 707360..708145
/gene="NNT1"
/locus_tag="YLR285W"
/db_xref="GeneID:850991"
mRNA 707360..708145
/gene="NNT1"
/locus_tag="YLR285W"
/product="Nnt1p"
/transcript_id="NM_001182172.1"
/db_xref="GI:296146815"
/db_xref="GeneID:850991"
CDS 707360..708145
/gene="NNT1"
/locus_tag="YLR285W"
/EC_number="2.1.1.1"
/note="S-adenosylmethionine-dependent methyltransferase;
has a role in rDNA silencing and in lifespan
determination"
/codon_start=1
/product="Nnt1p"
/protein_id="NP_013387.1"
/db_xref="GI:6323315"
/db_xref="SGD:S000004275"
/db_xref="GeneID:850991"
/translation="MSDIESLGEAAGLFEEPEDFLPPPPKPHFAEYQRSHITKESKSD
VKDIKLRLVGTSPLWGHLLWNAGIYTANHLDSHPELIKGKTVLELGAAAALPSVICAL
NGAQMVVSTDYPDPDLMQNIDYNIKSNVPEDFNNVSTEGYIWGNDYSPLLAHIEKIGN
NNGKFDLIILSDLVFNHTEHHKLLQTTKDLLAEKGQALVVFSPHRPKLLEKDLEFFEL
AKNEFHLVPQLIEMVNWKPMFDEDEETIEVRSRVYAYYLTHEK"
gene complement(708168..708338)
/locus_tag="YLR285C-A"
/db_xref="GeneID:1466418"
mRNA complement(708168..708338)
/locus_tag="YLR285C-A"
/product="hypothetical protein"
/transcript_id="NM_001184567.1"
/db_xref="GI:296146816"
/db_xref="GeneID:1466418"
CDS complement(708168..708338)
/locus_tag="YLR285C-A"
/note="hypothetical protein; identified by fungal homology
and RT-PCR"
/codon_start=1
/product="hypothetical protein"
/protein_id="NP_878130.1"
/db_xref="GI:33438842"
/db_xref="SGD:S000028569"
/db_xref="GeneID:1466418"
/translation="MFLRFYNRLLYIYNELFNFLRFTVFLPFCEFVPHHDLFYLIVTY
QRTLVYKHKNDC"
gene complement(708448..710136)
/gene="CTS1"
/locus_tag="YLR286C"
/db_xref="GeneID:850992"
mRNA complement(708448..710136)
/gene="CTS1"
/locus_tag="YLR286C"
/product="Cts1p"
/transcript_id="NM_001182173.1"
/db_xref="GI:296146817"
/db_xref="GeneID:850992"
CDS complement(708448..710136)
/gene="CTS1"
/locus_tag="YLR286C"
/EC_number="3.2.1.14"
/note="Endochitinase, required for cell separation after
mitosis; transcriptional activation during the G1 phase of
the cell cycle is mediated by transcription factor Ace2p"
/codon_start=1
/product="Cts1p"
/protein_id="NP_013388.1"
/db_xref="GI:6323316"
/db_xref="SGD:S000004276"
/db_xref="GeneID:850992"
/translation="MSLLYIILLFTQFLLLPTDAFDRSANTNIAVYWGQNSAGTQESL
ATYCESSDADIFLLSFLNQFPTLGLNFANACSDTFSDGLLHCTQIAEDIETCQSLGKK
VLLSLGGASGSYLFSDDSQAETFAQTLWDTFGEGTGASERPFDSAVVDGFDFDIENNN
EVGYSALATKLRTLFAEGTKQYYLSAAPQCPYPDASVGDLLENADIDFAFIQFYNNYC
SVSGQFNWDTWLTYAQTVSPNKNIKLFLGLPGSASAAGSGYISDTSLLESTIADIASS
SSFGGIALWDASQAFSNELNGEPYVEILKNLLTSASQTATTTVATSKTSAASTSSAST
SSASTSQKKTTQSTTSTQSKSKVTLSPTASSAIKTSITQTTKTLTSSTKTKSSLGTTT
TESTLNSVAITSMKTTLSSQITSAALVTPQTTTTSIVSSAPIQTAITSTLSPATKSSS
VVSLQTATTSTLSPTTTSTSSGSTSSGSTSSDSTARTLAKELNAQYAAGKLNGKSTCT
EGEIACSADGKFAVCDHSAWVYMECASGTTCYAYDSGDSVYTQCNFSYLESNYF"
gene complement(710991..712058)
/locus_tag="YLR287C"
/db_xref="GeneID:850993"
mRNA complement(710991..712058)
/locus_tag="YLR287C"
/product="hypothetical protein"
/transcript_id="NM_001182174.1"
/db_xref="GI:296146818"
/db_xref="GeneID:850993"
CDS complement(710991..712058)
/locus_tag="YLR287C"
/note="hypothetical protein; green fluorescent protein
(GFP)-fusion protein localizes to the cytoplasm; YLR287C
is not an essential gene"
/codon_start=1
/product="hypothetical protein"
/protein_id="NP_013389.1"
/db_xref="GI:6323317"
/db_xref="SGD:S000004277"
/db_xref="GeneID:850993"
/translation="MSTGSSDRKDDVKLLELLNSIDEQFLVPYKKPEDLRKISSTTKL
QGSTPTKELDKLASVLKAHCTKIGIVCKPGTFDNNHKVVITEIQNFSRPLFYLLSLFP
LFYNNKDCPKYFTDQLDESTLQLLDGLRDFIAELQERLKNDENASLDKERLTSVGKIF
NACDSLSNCSKAGPYGILANILKDNVAIMDDTMNEIKEWLEEPDFSANSDDIFLDFED
SESESDSQKEEFDQEKVYENIKLFFDGFTRKIKLIKLLVSTFRKTLVSKDFTPKRNQA
ETLDSIHTYLKEIQLLLDEVVSTVQFEPKNFTNEEVKEEQAALVAVTKKVLIQMSKLY
EGDPKRKKWIDTWEIKFNELF"
gene complement(712537..713158)
/gene="RPS30A"
/locus_tag="YLR287C-A"
/db_xref="GeneID:850994"
mRNA complement(join(712537..712725,713156..713158))
/gene="RPS30A"
/locus_tag="YLR287C-A"
/product="ribosomal 40S subunit protein S30A"
/transcript_id="NM_001182175.1"
/db_xref="GI:296146819"
/db_xref="GeneID:850994"
CDS complement(join(712537..712725,713156..713158))
/gene="RPS30A"
/locus_tag="YLR287C-A"
/note="Protein component of the small (40S) ribosomal
subunit; homologous to mammalian ribosomal protein S30, no
bacterial homolog; RPS30A has a paralog, RPS30B, that
arose from the whole genome duplication"
/codon_start=1
/product="ribosomal 40S subunit protein S30A"
/protein_id="NP_013390.1"
/db_xref="GI:6323318"
/db_xref="SGD:S000004278"
/db_xref="GeneID:850994"
/translation="MAKVHGSLARAGKVKSQTPKVEKTEKPKKPKGRAYKRLLYTRRF
VNVTLVNGKRRMNPGPSVQ"
gene complement(713480..714904)
/gene="MEC3"
/locus_tag="YLR288C"
/gene_synonym="PIP3; PSO9"
/db_xref="GeneID:850995"
mRNA complement(713480..714904)
/gene="MEC3"
/locus_tag="YLR288C"
/gene_synonym="PIP3; PSO9"
/product="Mec3p"
/transcript_id="NM_001182176.1"
/db_xref="GI:296146820"
/db_xref="GeneID:850995"
CDS complement(713480..714904)
/gene="MEC3"
/locus_tag="YLR288C"
/gene_synonym="PIP3; PSO9"
/note="DNA damage and meiotic pachytene checkpoint
protein; subunit of a heterotrimeric complex
(Rad17p-Mec3p-Ddc1p) that forms a sliding clamp, loaded
onto partial duplex DNA by a clamp loader complex; homolog
of human and S. pombe Hus1"
/codon_start=1
/product="Mec3p"
/protein_id="NP_013391.1"
/db_xref="GI:6323319"
/db_xref="SGD:S000004279"
/db_xref="GeneID:850995"
/translation="MKLKLIVNGCEAPDDYKLLRTTINTVASLRKTAILRFNSERLTI
ISTPKSSLNSSNNGTILRGDTGQLWCTIPHDVFRLYTVISARELNTITMECNCDSLLS
VFKRYDRVMNQGSSSNMTIKLQSMPEWNTNNGTLSGGTAGGVDTTSKPNPICALGITF
EEIVHTSGPNDAIVMNGGVDEHNGLPTTVGTGNLLASNKVIMHSFKVPVKLLFRAQDT
RIQEPMINYIQLMMYKLPPISGEFGSAFHGFIRRVERYSNVNHIHLMGVKKKEHGNEG
DDVELKIIVNELDWHLEICWNGPLDSVIQRQEGLTDNPSQNQHIDTDGRQEEGSLPII
EADKPMSSLYTNTRDREMEENIRYDEDLLRIEDSSIADTRGNIYTADTSGDTEFNDIS
VMVEKAEQESSSTHEVIIRCKDWKVCSKLYAAFEEVVLAISHDESCVFHCSLDRGSLE
DSEDVEKPRERGQIIYYIARSKGL"
gene 715089..717026
/gene="GUF1"
/locus_tag="YLR289W"
/db_xref="GeneID:850996"
mRNA 715089..717026
/gene="GUF1"
/locus_tag="YLR289W"
/product="Guf1p"
/transcript_id="NM_001182177.1"
/db_xref="GI:296146821"
/db_xref="GeneID:850996"
CDS 715089..717026
/gene="GUF1"
/locus_tag="YLR289W"
/note="Mitochondrial matrix GTPase that associates with
mitochondrial ribosomes; important for translation under
temperature and nutrient stress; may have a role in
translational fidelity; similar to bacterial LepA
elongation factor"
/codon_start=1
/product="Guf1p"
/protein_id="NP_013392.1"
/db_xref="GI:6323320"
/db_xref="SGD:S000004280"
/db_xref="GeneID:850996"
/translation="MLKFRIRPVRHIRCYKRHAYFLRYNHTTTPAQKLQAQIEQIPLE
NYRNFSIVAHVDHGKSTLSDRLLEITHVIDPNARNKQVLDKLEVERERGITIKAQTCS
MFYKDKRTGKNYLLHLIDTPGHVDFRGEVSRSYASCGGAILLVDASQGIQAQTVANFY
LAFSLGLKLIPVINKIDLNFTDVKQVKDQIVNNFELPEEDIIGVSAKTGLNVEELLLP
AIIDRIPPPTGRPDKPFRALLVDSWYDAYLGAVLLVNIVDGSVRKNDKVICAQTKEKY
EVKDIGIMYPDRTSTGTLKTGQVGYLVLGMKDSKEAKIGDTIMHLSKVNETEVLPGFE
EQKPMVFVGAFPADGIEFKAMDDDMSRLVLNDRSVTLERETSNALGQGWRLGFLGSLH
ASVFRERLEKEYGSKLIITQPTVPYLVEFTDGKKKLITNPDEFPDGATKRVNVAAFHE
PFIEAVMTLPQEYLGSVIRLCDSNRGEQIDITYLNTNGQVMLKYYLPLSHLVDDFFGK
LKSVSRGFASLDYEDAGYRISDVVKLQLLVNGNAIDALSRVLHKSEVERVGREWVKKF
KEYVKSQLYEVVIQARANNKIIARETIKARRKDVLQKLHASDVSRRKKLLAKQKEGKK
HMKTVGNIQINQEAYQAFLRR"
gene complement(717145..717978)
/locus_tag="YLR290C"
/db_xref="GeneID:850997"
mRNA complement(717145..717978)
/locus_tag="YLR290C"
/product="hypothetical protein"
/transcript_id="NM_001182178.1"
/db_xref="GI:296146822"
/db_xref="GeneID:850997"
CDS complement(717145..717978)
/locus_tag="YLR290C"
/note="hypothetical protein; the authentic, non-tagged
protein is detected in highly purified mitochondria in
high-throughput studies; YLR290C is not an essential gene"
/codon_start=1
/product="hypothetical protein"
/protein_id="NP_013393.1"
/db_xref="GI:6323321"
/db_xref="SGD:S000004281"
/db_xref="GeneID:850997"
/translation="MIPKLIVFGGNGFLGKRICQEAVTSGYQVVSVSRSGKAPHSNEL
NDKQWMQEVQWTAADIFKPDSYHELLNNATNVVHSLGILLENENYKQTLSKSPTYDSK
SRLLSFGAGPNPLKKSSPYFTYEMMNKQSAIILADTFKQKILKKSKKEQEKANQRSFT
YISADKGFPLIPSGYINSKREAEIELEKMQRYFRPIIVRPGFMFDEHRNAIGPRSFIH
TALELLYCGNKFLLRNKLQLLNDLIRPTVSTQQVSKSVLKNIENPDFKGVVTLEEILK
A"
gene complement(718317..719462)
/gene="GCD7"
/locus_tag="YLR291C"
/db_xref="GeneID:850998"
mRNA complement(718317..719462)
/gene="GCD7"
/locus_tag="YLR291C"
/product="Gcd7p"
/transcript_id="NM_001182179.1"
/db_xref="GI:296146823"
/db_xref="GeneID:850998"
CDS complement(718317..719462)
/gene="GCD7"
/locus_tag="YLR291C"
/note="Beta subunit of the translation initiation factor
eIF2B, the guanine-nucleotide exchange factor for eIF2;
activity subsequently regulated by phosphorylated eIF2;
first identified as a negative regulator of GCN4
expression"
/codon_start=1
/product="Gcd7p"
/protein_id="NP_013394.1"
/db_xref="GI:6323322"
/db_xref="SGD:S000004282"
/db_xref="GeneID:850998"
/translation="MSSQAFTSVHPNAATSDVNVTIDTFVAKLKRRQVQGSYAIALET
LQLLMRFISAARWNHVNDLIEQIRDLGNSLEKAHPTAFSCGNVIRRILAVLRDEVEED
TMSTTVTSTSVAEPLISSMFNLLQKPEQPHQNRKNSSGSSSMKTKTDYRQVAIQGIKD
LIDEIKNIDEGIQQIAIDLIHDHEILLTPTPDSKTVLKFLITARERSNRTFTVLVTEG
FPNNTKNAHEFAKKLAQHNIETLVVPDSAVFALMSRVGKVIIGTKAVFVNGGTISSNS
GVSSVCECAREFRTPVFAVAGLYKLSPLYPFDVEKFVEFGGSQRILPRMDPRKRLDTV
NQITDYVPPENIDIYITNVGGFNPSFIYRIAWDNYKQIDVHLDKNKA"
gene complement(719789..720370)
/gene="SEC72"
/locus_tag="YLR292C"
/gene_synonym="SEC67; SIM2"
/db_xref="GeneID:850999"
mRNA complement(719789..720370)
/gene="SEC72"
/locus_tag="YLR292C"
/gene_synonym="SEC67; SIM2"
/product="Sec72p"
/transcript_id="NM_001182180.1"
/db_xref="GI:296146824"
/db_xref="GeneID:850999"
CDS complement(719789..720370)
/gene="SEC72"
/locus_tag="YLR292C"
/gene_synonym="SEC67; SIM2"
/note="Non-essential subunit of Sec63 complex (Sec63p,
Sec62p, Sec66p and Sec72p); with Sec61 complex, Kar2p/BiP
and Lhs1p forms a channel competent for SRP-dependent and
post-translational SRP-independent protein targeting and
import into the ER"
/codon_start=1
/product="Sec72p"
/protein_id="NP_013395.1"
/db_xref="GI:6323323"
/db_xref="SGD:S000004283"
/db_xref="GeneID:850999"
/translation="MVTLEYNANSKLITASDAVVALSTETNIDQINVLTTSLIGETNP
NFTPQPNEALSKMIKGLFESGMKNLQQKKLNEALKNVSLAIEMAQRKRAPWEAFAIQL
PELHFMLRSKIDLCLILGKHLEALQDLDFLLGTGLIQPDVFVRKADCLLKLRQWEEAR
ATCERGLALAPEDMKLRALLIETARNLAEYNGE"
gene complement(720771..721430)
/gene="GSP1"
/locus_tag="YLR293C"
/gene_synonym="CNR1; CST17"
/db_xref="GeneID:851000"
mRNA complement(720771..721430)
/gene="GSP1"
/locus_tag="YLR293C"
/gene_synonym="CNR1; CST17"
/product="Gsp1p"
/transcript_id="NM_001182181.1"
/db_xref="GI:296146825"
/db_xref="GeneID:851000"
CDS complement(720771..721430)
/gene="GSP1"
/locus_tag="YLR293C"
/gene_synonym="CNR1; CST17"
/note="Ran GTPase, GTP binding protein (mammalian Ranp
homolog) involved in the maintenance of nuclear
organization, RNA processing and transport; regulated by
Srm1p, Rna1p, Yrb1p, Yrb2p, Yrp4p, Yrb30p, Cse1p and
Kap95p; yeast Gsp2p homolog"
/codon_start=1
/product="Gsp1p"
/protein_id="NP_013396.1"
/db_xref="GI:6323324"
/db_xref="SGD:S000004284"
/db_xref="GeneID:851000"
/translation="MSAPAANGEVPTFKLVLVGDGGTGKTTFVKRHLTGEFEKKYIAT
IGVEVHPLSFYTNFGEIKFDVWDTAGQEKFGGLRDGYYINAQCAIIMFDVTSRITYKN
VPNWHRDLVRVCENIPIVLCGNKVDVKERKVKAKTITFHRKKNLQYYDISAKSNYNFE
KPFLWLARKLAGNPQLEFVASPALAPPEVQVDEQLMQQYQQEMEQATALPLPDEDDAD
L"
rep_origin 720784..721418
/note="ARS1221;
Putative replication origin, identified in multiple array
studies, not yet confirmed by plasmid-based assay"
/db_xref="SGD:S000130184"
gene complement(721999..722373)
/gene="ATP14"
/locus_tag="YLR295C"
/db_xref="GeneID:851002"
mRNA complement(721999..722373)
/gene="ATP14"
/locus_tag="YLR295C"
/product="F1F0 ATP synthase subunit h"
/transcript_id="NM_001182183.1"
/db_xref="GI:296146826"
/db_xref="GeneID:851002"
CDS complement(721999..722373)
/gene="ATP14"
/locus_tag="YLR295C"
/EC_number="3.6.3.14"
/note="Subunit h of the F0 sector of mitochondrial F1F0
ATP synthase; F1F0 ATP synthase is a large, evolutionarily
conserved enzyme complex required for ATP synthesis;
protein abundance increases in response to DNA replication
stress"
/codon_start=1
/product="F1F0 ATP synthase subunit h"
/protein_id="NP_013398.1"
/db_xref="GI:6323326"
/db_xref="SGD:S000004286"
/db_xref="GeneID:851002"
/translation="MFPIASRRILLNASVLPLRLCNRNFTTTRISYNVIQDLYLRELK
DTKLAPSTLQDAEGNVKPWNPPQKPNLPELELQGPEALKAYTEQNVETAHVAKESEEG
ESEPIEEDWLVLDDAEETKESH"
gene 724044..724433
/locus_tag="YLR297W"
/db_xref="GeneID:851004"
mRNA 724044..724433
/locus_tag="YLR297W"
/product="hypothetical protein"
/transcript_id="NM_001182185.1"
/db_xref="GI:296146827"
/db_xref="GeneID:851004"
CDS 724044..724433
/locus_tag="YLR297W"
/note="hypothetical protein; green fluorescent protein
(GFP)-fusion protein localizes to the vacuole; YLR297W is
not an essential gene; induced by treatment with
8-methoxypsoralen and UVA irradiation; relocalizes from
nucleus to vacuole upon DNA replication stress"
/codon_start=1
/product="hypothetical protein"
/protein_id="NP_013400.1"
/db_xref="GI:6323328"
/db_xref="SGD:S000004288"
/db_xref="GeneID:851004"
/translation="MVEGDFVDEQSNIALLSSKSMCGDHHSVKNSIGDEIFKLLTKIL
NSDEKASGDVHTLVSGTPDLSNFNLDNEPLENILAVFIISFIIVVVGVLLLGLIGMIF
ISLRSGSSNDKKLQSNDEEKQALAEKA"
gene complement(724721..725416)
/gene="YHC1"
/locus_tag="YLR298C"
/db_xref="GeneID:851005"
mRNA complement(724721..725416)
/gene="YHC1"
/locus_tag="YLR298C"
/product="Yhc1p"
/transcript_id="NM_001182186.1"
/db_xref="GI:296146828"
/db_xref="GeneID:851005"
CDS complement(724721..725416)
/gene="YHC1"
/locus_tag="YLR298C"
/note="Component of the U1 snRNP complex required for
pre-mRNA splicing; putative ortholog of human U1C protein,
which is involved in formation of a complex between U1
snRNP and the pre-mRNA 5' splice site"
/codon_start=1
/product="Yhc1p"
/protein_id="NP_013401.1"
/db_xref="GI:6323329"
/db_xref="SGD:S000004289"
/db_xref="GeneID:851005"
/translation="MTRYYCEYCHSYLTHDTLSVRKSHLVGKNHLRITADYYRNKARD
IINKHNHKRRHIGKRGRKERENSSQNETLKVTCLSNKEKRHIMHVKKMNQKELAQTSI
DTLKLLYDGSPGYSKVFVDANRFDIGDLVKASKLPQRANEKSAHHSFKQTSRSRDETC
ESNPFPRLNNPKKLEPPKILSQWSNTIPKTSIFYSVDILQTTIKESKKRMHSDGIRKP
SSANGYKRRRYGN"
gene 726069..728051
/gene="ECM38"
/locus_tag="YLR299W"
/gene_synonym="CIS2"
/db_xref="GeneID:851006"
mRNA 726069..728051
/gene="ECM38"
/locus_tag="YLR299W"
/gene_synonym="CIS2"
/product="gamma-glutamyltransferase"
/transcript_id="NM_001182187.1"
/db_xref="GI:296146829"
/db_xref="GeneID:851006"
CDS 726069..728051
/gene="ECM38"
/locus_tag="YLR299W"
/gene_synonym="CIS2"
/EC_number="2.3.2.2"
/note="Gamma-glutamyltranspeptidase, major
glutathione-degrading enzyme; involved in detoxification
of electrophilic xenobiotics; expression induced mainly by
nitrogen starvation"
/codon_start=1
/product="gamma-glutamyltransferase"
/protein_id="NP_013402.1"
/db_xref="GI:6323330"
/db_xref="SGD:S000004290"
/db_xref="GeneID:851006"
/translation="MLLCNRKVPKTLNTCFILHIFTLLTLGVLVSGMPSKMVSFASQE
TLQRINNLLRGSANRDVDIIAEYLKKDDDDDGGDKDHHNIDIDPLPRRPSLTPDRQLL
KVGLHGAISSDLEVCSNLTINEVLLKFPGSNAADAAVTQALCKGMVNFFNSGIGGGGY
VVFSGKDDEDHLSIDFREKAPMDSHKFMFENCSLCSKIGGLAVGVPGELMGLYRLFKE
RGSGQVDWRDLIEPVAKLGSVGWQIGEALGATLELYEDVFLTLKEDWSFVLNSTHDGV
LKEGDWIKRPALSNMLMELAKNGSVAPFYDPDHWIAKSMIDTVAKYNGIMNLQDVSSY
DVHVTKPLSMKIRKGANFIPDNDMTVLTSSGSSSGAALLAALRIMDNFQNQEGGDYEK
ETTYHLLESMKWMASARSRLGDFEGEALPKHIEEVLDPEWALKAVKSIKRNSQDGNFK
TLENWTLYDPAYDINNPHGTAHFSIVDSHGNAVSLTTTINLLFGSLVHDPKTGVIFNN
EMDDFAQFNKSNSFELAPSIYNFPEPGKRPLSSTAPTIVLSELGIPDLVVGASGGSRI
TTSVLQTIVRTYWYNMPILETIAYPRIHHQLLPDRIELESFPMIGKAVLSTLKEMGYT
MKEVFPKSVVNAIRNVRGEWHAVSDYWRKRGISSVY"
gene 728955..730301
/gene="EXG1"
/locus_tag="YLR300W"
/gene_synonym="BGL1"
/db_xref="GeneID:851007"
mRNA 728955..730301
/gene="EXG1"
/locus_tag="YLR300W"
/gene_synonym="BGL1"
/product="Exg1p"
/transcript_id="NM_001182188.1"
/db_xref="GI:296146830"
/db_xref="GeneID:851007"
CDS 728955..730301
/gene="EXG1"
/locus_tag="YLR300W"
/gene_synonym="BGL1"
/EC_number="3.2.1.58"
/note="Major exo-1,3-beta-glucanase of the cell wall,
involved in cell wall beta-glucan assembly; exists as
three differentially glycosylated isoenzymes"
/codon_start=1
/product="Exg1p"
/protein_id="NP_013403.1"
/db_xref="GI:6323331"
/db_xref="SGD:S000004291"
/db_xref="GeneID:851007"
/translation="MLSLKTLLCTLLTVSSVLATPVPARDPSSIQFVHEENKKRYYDY
DHGSLGEPIRGVNIGGWLLLEPYITPSLFEAFRTNDDNDEGIPVDEYHFCQYLGKDLA
KSRLQSHWSTFYQEQDFANIASQGFNLVRIPIGYWAFQTLDDDPYVSGLQESYLDQAI
GWARNNSLKVWVDLHGAAGSQNGFDNSGLRDSYKFLEDSNLAVTTNVLNYILKKYSAE
EYLDTVIGIELINEPLGPVLDMDKMKNDYLAPAYEYLRNNIKSDQVIIIHDAFQPYNY
WDDFMTENDGYWGVTIDHHHYQVFASDQLERSIDEHIKVACEWGTGVLNESHWTVCGE
FAAALTDCTKWLNSVGFGARYDGSWVNGDQTSSYIGSCANNDDIAYWSDERKENTRRY
VEAQLDAFEMRGGWIIWCYKTESSLEWDAQRLMFNGLFPQPLTDRKYPNQCGTISN"
gene 730825..731559
/gene="HRI1"
/locus_tag="YLR301W"
/db_xref="GeneID:851008"
mRNA 730825..731559
/gene="HRI1"
/locus_tag="YLR301W"
/product="Hri1p"
/transcript_id="NM_001182189.1"
/db_xref="GI:296146831"
/db_xref="GeneID:851008"
CDS 730825..731559
/gene="HRI1"
/locus_tag="YLR301W"
/note="hypothetical protein that interacts with Sec72p and
Hrr25p"
/codon_start=1
/product="Hri1p"
/protein_id="NP_013404.1"
/db_xref="GI:6323332"
/db_xref="SGD:S000004292"
/db_xref="GeneID:851008"
/translation="MPALLKRLLFQVGPHPNERTFTLSSVSTDGHYISLRPFVKPSGD
ELSFPFEWAFAGTNETVKANDQGNGVVTQDFNFWLDTNVYLNVPNTHRGEVNTTWKNW
DSGCVEETGAVYPFGADKESVSFRELWQPVDPSREDLVIVSPNNEKFSSNARSIVLKV
TDEAYDGLVIVIGRWIQGFLSQKNNNTIEGLNFIRLLEKDSGKSEFLLSYGKEVNKIP
QSYENLKKGSTVTSNGLNWEVIEYHA"
LTR complement(731668..732000)
/note="Ty2 LTR"
/db_xref="SGD:S000007072"
gene 732090..732190
/locus_tag="tL(UAG)L2"
/db_xref="GeneID:851009"
tRNA join(732090..732127,732147..732190)
/locus_tag="tL(UAG)L2"
/product="tRNA-Leu"
/note="Leucine tRNA (tRNA-Leu), predicted by tRNAscan-SE
analysis"
/db_xref="SGD:S000006656"
/db_xref="GeneID:851009"
gene 732542..733876
/gene="MET17"
/locus_tag="YLR303W"
/gene_synonym="MET15; MET25"
/db_xref="GeneID:851010"
mRNA 732542..733876
/gene="MET17"
/locus_tag="YLR303W"
/gene_synonym="MET15; MET25"
/product="bifunctional cysteine
synthase/O-acetylhomoserine aminocarboxypropyltransferase
MET17"
/transcript_id="NM_001182191.1"
/db_xref="GI:296146832"
/db_xref="GeneID:851010"
CDS 732542..733876
/gene="MET17"
/locus_tag="YLR303W"
/gene_synonym="MET15; MET25"
/EC_number="2.5.1.49"
/EC_number="2.5.1.47"
/note="Methionine and cysteine synthase (O-acetyl
homoserine-O-acetyl serine sulfhydrylase), required for
sulfur amino acid synthesis"
/codon_start=1
/product="bifunctional cysteine
synthase/O-acetylhomoserine aminocarboxypropyltransferase
MET17"
/protein_id="NP_013406.1"
/db_xref="GI:6323333"
/db_xref="SGD:S000004294"
/db_xref="GeneID:851010"
/translation="MPSHFDTVQLHAGQENPGDNAHRSRAVPIYATTSYVFENSKHGS
QLFGLEVPGYVYSRFQNPTSNVLEERIAALEGGAAALAVSSGQAAQTLAIQGLAHTGD
NIVSTSYLYGGTYNQFKISFKRFGIEARFVEGDNPEEFEKVFDERTKAVYLETIGNPK
YNVPDFEKIVAIAHKHGIPVVVDNTFGAGGYFCQPIKYGADIVTHSATKWIGGHGTTI
GGIIVDSGKFPWKDYPEKFPQFSQPAEGYHGTIYNEAYGNLAYIVHVRTELLRDLGPL
MNPFASFLLLQGVETLSLRAERHGENALKLAKWLEQSPYVSWVSYPGLASHSHHENAK
KYLSNGFGGVLSFGVKDLPNADKETDPFKLSGAQVVDNLKLASNLANVGDAKTLVIAP
YFTTHKQLNDKEKLASGVTKDLIRVSVGIEFIDDIIADFQQSFETVFAGQKP"
LTR complement(734501..734671)
/note="Ty1 LTR"
/db_xref="SGD:S000007073"
gene 734802..734875
/locus_tag="tI(AAU)L1"
/db_xref="GeneID:851012"
tRNA 734802..734875
/locus_tag="tI(AAU)L1"
/product="tRNA-Ile"
/note="Isoleucine tRNA (tRNA-Ile), predicted by
tRNAscan-SE analysis"
/db_xref="SGD:S000006607"
/db_xref="GeneID:851012"
gene complement(735212..737548)
/gene="ACO1"
/locus_tag="YLR304C"
/gene_synonym="GLU1"
/db_xref="GeneID:851013"
mRNA complement(735212..737548)
/gene="ACO1"
/locus_tag="YLR304C"
/gene_synonym="GLU1"
/product="aconitate hydratase ACO1"
/transcript_id="NM_001182192.1"
/db_xref="GI:296146833"
/db_xref="GeneID:851013"
CDS complement(735212..737548)
/gene="ACO1"
/locus_tag="YLR304C"
/gene_synonym="GLU1"
/EC_number="4.2.1.3"
/note="Aconitase, required for the tricarboxylic acid
(TCA) cycle and also independently required for
mitochondrial genome maintenance; phosphorylated;
component of the mitochondrial nucleoid; mutation leads to
glutamate auxotrophy"
/codon_start=1
/product="aconitate hydratase ACO1"
/protein_id="NP_013407.1"
/db_xref="GI:6323335"
/db_xref="SGD:S000004295"
/db_xref="GeneID:851013"
/translation="MLSARSAIKRPIVRGLATVSNLTRDSKVNQNLLEDHSFINYKQN
VETLDIVRKRLNRPFTYAEKILYGHLDDPHGQDIQRGVSYLKLRPDRVACQDATAQMA
ILQFMSAGLPQVAKPVTVHCDHLIQAQVGGEKDLKRAIDLNKEVYDFLASATAKYNMG
FWKPGSGIIHQIVLENYAFPGALIIGTDSHTPNAGGLGQLAIGVGGADAVDVMAGRPW
ELKAPKILGVKLTGKMNGWTSPKDIILKLAGITTVKGGTGKIVEYFGDGVDTFSATGM
GTICNMGAEIGATTSVFPFNKSMIEYLEATGRGKIADFAKLYHKDLLSADKDAEYDEV
VEIDLNTLEPYINGPFTPDLATPVSKMKEVAVANNWPLDVRVGLIGSCTNSSYEDMSR
SASIVKDAAAHGLKSKTIFTVTPGSEQIRATIERDGQLETFKEFGGIVLANACGPCIG
QWDRRDIKKGDKNTIVSSYNRNFTSRNDGNPQTHAFVASPELVTAFAIAGDLRFNPLT
DKLKDKDGNEFMLKPPHGDGLPQRGYDAGENTYQAPPADRSTVEVKVSPTSDRLQLLK
PFKPWDGKDAKDMPILIKAVGKTTTDHISMAGPWLKYRGHLENISNNYMIGAINAENK
KANCVKNVYTGEYKGVPDTARDYRDQGIKWVVIGDENFGEGSSREHAALEPRFLGGFA
IITKSFARIHETNLKKQGLLPLNFKNPADYDKINPDDRIDILGLAELAPGKPVTMRVH
PKNGKPWDAVLTHTFNDEQIEWFKYGSALNKIKADEKK"
gene complement(738161..743863)
/gene="STT4"
/locus_tag="YLR305C"
/db_xref="GeneID:851014"
mRNA complement(738161..743863)
/gene="STT4"
/locus_tag="YLR305C"
/product="1-phosphatidylinositol 4-kinase STT4"
/transcript_id="NM_001182193.1"
/db_xref="GI:296146834"
/db_xref="GeneID:851014"
CDS complement(738161..743863)
/gene="STT4"
/locus_tag="YLR305C"
/EC_number="2.7.1.67"
/note="Phosphatidylinositol-4-kinase that functions in the
Pkc1p protein kinase pathway; required for normal vacuole
morphology, cell wall integrity, and actin cytoskeleton
organization"
/codon_start=1
/product="1-phosphatidylinositol 4-kinase STT4"
/protein_id="NP_013408.1"
/db_xref="GI:6323336"
/db_xref="SGD:S000004296"
/db_xref="GeneID:851014"
/translation="MRFTRGLKASSSLRAKAIGRLTKLSTGAPNDQNSNGTTLDLITH
TLPIFYSTNTSKIYTIPLTLSEWEVLTSLCVAIPTTLDLVETMLKEIIAPYFLETPRQ
RISDVLSSKFKLEQMRNPIELLTFQLTKFMIQACEQYPVLYENIGGIISTYFERVLKI
FTIKQSGLLSLVGFINAFIQFPNSTELTKFTWKKLAKLVLRGSFLNEVDKILNSSATF
TNDSIVQYYDAGNELSSAYLLELISRLQVSLISHLLNTSHVGANLSEFLLNQQYQFYK
FDQEVADENDDTKCIDDFFFNVRSNKQFFTDMCKISLQFCSESHILDLSTDNRARFSF
DTRAHYLQTLCLIPFIEDTESELFESFTNVVSESIDKFFLSDVVTPSLIKAIVASASL
LNFFTEKLSLTLIRMFPLLVASPHITTETVNDVAKIFTTGLYPLNEDAIVSTIYSMNN
LLAVSEDGSPVPVLRERQLTITSGKNIEKDYFPLRNSSASLDGTGALLGNTTVGQLSS
HDVNSGATMTYHASLISNCVAATTTIASYYNTQSITALTISILTQKVNSMSKELDGVI
LNSLARLAPNTSLTEFSLLLKFFKSRTVIATKIDDSALLKNIIKAKCVISKELLARHF
SSDLYFMYLHDLLDSIIASGEVERLEHHRPQTEISRVADQIATYLEPLAALLPVPGDT
PLDINKDEVTTNKFRNAWFNFVIHGYHLGGPIVKRNFSFLLTIAYNSPPLASEFPANN
KELSLEMNTILRRGSSNENIKQQKQQITEYFNTNIVQYRTTSSSKIMFLAAAVLLETI
RCEAGDCSKTLLYFSDPSILSGSIEKCIAVLSVSMIRKYARLIQKGNDAIFNSKMIAQ
QLNNLLLCLSHREPTLQDAAFHACEIFIRSIPSSLCHHLSLYTLLDMLTALFDSILDS
EAHKFEPRYEFKLKHSKTTILVPSSSSWRATTLSRLHKSAKEWVRILLNRSNQDTKIL
LQSYISDLGEYSRLNSVEFGVSFAMDMAGLILPADKELSRLTYYGPEKPNTISGFISL
HSWRSKYLFDTAITSSPEDIKRQIGISTQNIRKNLTLGNKIITKDVTDFLDMATALLI
LGNGAPASLIYDIVHIPFEVFTSASLKIATNVWLTIITEKPEVAHLLLVEVCYCWMRS
IDDNIGLYSRDHDLKGEEYQKMEYSPYDKAGINRDAKNASQAMQPHLHVIKFFASHFE
GTLFQSDFLLKIFTKCALYGIKNLYKASLHPFARMIRHELLLFATLVLNASYKQGSKY
MGRLSQEITNGALSWFKRPVAWPFGSNELKIKADLSVTRDLFLQLNKLSSLMSRHCGK
DYKILNYFLASEIQQIQTWLTPTEKIEGADSNELTSDIVEATFAKDPTLAINLLQRCY
SKKAEDVLVGLVAKHALMCVGSPSALDLFIKGSHLSSKKDLHATLYWAPVSPLKSINL
FLPEWQGNSFILQFSIYSLESQDVNLAFFYVPQIVQCLRYDKTGYVERLILDTAKISV
LFSHQIIWNMLANCYKDDEGIQEDEIKPTLDRIRERMVSSFSQSHRDFYEREFEFFDE
VTGISGKLKPYIKKSKAEKKHKIDEEMSKIEVKPDVYLPSNPDGVVIDIDRKSGKPLQ
SHAKAPFMATFKIKKDVKDPLTGKNKEVEKWQAAIFKVGDDCRQDVLALQLISLFRTI
WSSIGLDVYVFPYRVTATAPGCGVIDVLPNSVSRDMLGREAVNGLYEYFTSKFGNEST
IEFQNARNNFVKSLAGYSVISYLLQFKDRHNGNIMYDDQGHCLHIDFGFIFDIVPGGI
KFEAVPFKLTKEMVKVMGGSPQTPAYLDFEELCIKAYLAARPHVEAIIECVNPMLGSG
LPCFKGHKTIRNLRARFQPQKTDHEAALYMKALIRKSYESIFTKGYDEFQRLTNGIPY
"
gene 744151..744851
/gene="UBC12"
/locus_tag="YLR306W"
/db_xref="GeneID:851015"
mRNA join(744151..744153,744288..744851)
/gene="UBC12"
/locus_tag="YLR306W"
/product="NEDD8-conjugating protein UBC12"
/transcript_id="NM_001182194.1"
/db_xref="GI:296146835"
/db_xref="GeneID:851015"
CDS join(744151..744153,744288..744851)
/gene="UBC12"
/locus_tag="YLR306W"
/EC_number="6.3.2.-"
/note="Enzyme that mediates the conjugation of Rub1p, a
ubiquitin-like protein, to other proteins; related to E2
ubiquitin-conjugating enzymes"
/codon_start=1
/product="NEDD8-conjugating protein UBC12"
/protein_id="NP_013409.1"
/db_xref="GI:6323337"
/db_xref="SGD:S000004297"
/db_xref="GeneID:851015"
/translation="MLKLRQLQKKKQKENENSSSIQPNLSAARIRLKRDLDSLDLPPT
VTLNVITSPDSADRSQSPKLEVIVRPDEGYYNYGSINFNLDFNEVYPIEPPKVVCLKK
IFHPNIDLKGNVCLNILREDWSPALDLQSIITGLLFLFLEPNPNDPLNKDAAKLLCEG
EKEFAEAVRLTMSGGSIEHVKYDNIVSP"
rep_origin 744943..745179
/note="ARS1223;
Autonomously Replicating Sequence; replication capacity
dependent upon Sum1p"
/db_xref="SGD:S000118479"
gene 745620..746525
/gene="CDA1"
/locus_tag="YLR307W"
/db_xref="GeneID:851016"
mRNA 745620..746525
/gene="CDA1"
/locus_tag="YLR307W"
/product="chitin deacetylase CDA1"
/transcript_id="NM_001182195.1"
/db_xref="GI:296146836"
/db_xref="GeneID:851016"
CDS 745620..746525
/gene="CDA1"
/locus_tag="YLR307W"
/EC_number="3.5.1.41"
/note="Chitin deacetylase, together with Cda2p involved in
the biosynthesis ascospore wall component, chitosan;
required for proper rigidity of the ascospore wall"
/codon_start=1
/product="chitin deacetylase CDA1"
/protein_id="NP_013410.1"
/db_xref="GI:6323338"
/db_xref="SGD:S000004298"
/db_xref="GeneID:851016"
/translation="MKIFNTIQSVLFAAFFLKQGNCLASNGSTALMGEVDMQTPFPEW
LTEFTNLTQWPGIDPPYIPLDYINLTEVPELDRYYPGQCPKISREQCSFDCYNCIDVD
DVTSCFKLSQTFDDGPAPATEALLKKLRQRTTFFVLGINTVNYPDIYEHILERGHLIG
THTWSHEFLPSLSNEEIVAQIEWSIWAMNATGKHFPKYFRPPYGAIDNRVRAIVKQFG
LTVVLWDLDTFDWKLITNDDFRTEEEILMDINTWKGKRKGLILEHDGARRTVEVAIKI
NELIGSDQLTIAECIGDTDYIERYD"
gene complement(746848..747111)
/locus_tag="YLR307C-A"
/db_xref="GeneID:1466419"
mRNA complement(746848..747111)
/locus_tag="YLR307C-A"
/product="hypothetical protein"
/transcript_id="NM_001184535.1"
/db_xref="GI:296146837"
/db_xref="GeneID:1466419"
CDS complement(746848..747111)
/locus_tag="YLR307C-A"
/codon_start=1
/product="hypothetical protein"
/protein_id="NP_878131.1"
/db_xref="GI:33438843"
/db_xref="SGD:S000028525"
/db_xref="GeneID:1466419"
/translation="MSLRNISMITKNLQTTAKCYVPKSSPTSTTIPVIRDASTTQCRR
ITTVINITSLKGYSPSPRTVHDKPIVICTDNEEVETVSEHVKV"
gene 747937..748875
/gene="CDA2"
/locus_tag="YLR308W"
/db_xref="GeneID:851017"
mRNA 747937..748875
/gene="CDA2"
/locus_tag="YLR308W"
/product="chitin deacetylase CDA2"
/transcript_id="NM_001182196.1"
/db_xref="GI:296146838"
/db_xref="GeneID:851017"
CDS 747937..748875
/gene="CDA2"
/locus_tag="YLR308W"
/EC_number="3.5.1.41"
/note="Chitin deacetylase, together with Cda1p involved in
the biosynthesis ascospore wall component, chitosan;
required for proper rigidity of the ascospore wall"
/codon_start=1
/product="chitin deacetylase CDA2"
/protein_id="NP_013411.1"
/db_xref="GI:6323339"
/db_xref="SGD:S000004299"
/db_xref="GeneID:851017"
/translation="MRIQLNTIDLQCIIALSCLGQFVHAEANREDLKQIDFQFPVLER
AATKTPFPDWLSAFTGLKEWPGLDPPYIPLDFIDFSQIPDYKEYDQNHCDSVPRDSCS
FDCHHCTEHDDVYTCSKLSQTFDDGPSASTTKLLDRLKHNSTFFNLGVNIVQHPDIYQ
RMQKEGHLIGSHTWSHVYLPNVSNEKIIAQIEWSIWAMNATGNHTPKWFRPPYGGIDN
RVRAITRQFGLQAVLWDHDTFDWSLLLNDSVITEQEILQNVINWNKSGTGLILEHDST
EKTVDLAIKINKLIGDDQSTVSHCVGGIDYIKEFLS"
gene complement(749034..751769)
/gene="IMH1"
/locus_tag="YLR309C"
/gene_synonym="SYS3"
/db_xref="GeneID:851018"
mRNA complement(749034..751769)
/gene="IMH1"
/locus_tag="YLR309C"
/gene_synonym="SYS3"
/product="Imh1p"
/transcript_id="NM_001182197.2"
/db_xref="GI:330443672"
/db_xref="GeneID:851018"
CDS complement(749034..751769)
/gene="IMH1"
/locus_tag="YLR309C"
/gene_synonym="SYS3"
/note="Protein involved in vesicular transport, mediates
transport between an endosomal compartment and the Golgi,
contains a Golgi-localization (GRIP) domain that interacts
with activated Arl1p-GTP to localize Imh1p to the Golgi"
/codon_start=1
/product="Imh1p"
/protein_id="NP_013412.1"
/db_xref="GI:6323340"
/db_xref="SGD:S000004300"
/db_xref="GeneID:851018"
/translation="MFKQLSQIGKNLTDELAKGLADDMSPTPSEQQIEDDKSGLPKEI
QAKLRKFEKYEQKYPLLLSAYKNEKLKSEKLEAVEKILAENTPISNIDDAVDTLPAFF
QDLNNKNNLLNDEIKRLTKQNSEIPESASSETLKDKEEEFLKKEQNYKNDIDDLKKKM
EALNIELDTVQKEKNDTVSGLREKIVALENILKEEREAKKQKEEVSISELKEELAIKN
HSLEDSRMKITELEQNLSSKSTIMEEKSSELAELNITLKEKERKLSELEKKMKELPKA
ISHQNVGNNNRRKKNRNKGKKNKGGITTGDISEEETVDNSINTEEYDKLKENLQELQE
KYKDCEDWKQKYEDIEAELKDAKELENSQLEKSAKELETLNTELIDTKKSLKEKNSEL
EEVRDMLRTVGNELVDAKDEIKESSSKQNEEVKTVKLELDDLRHKNATMIEAYEAKNT
ELRSKIELLSKKVEHLKNLCTEKEKEQTTSQNKVAKLNEEISQLTYEKSNITKELTSL
RTSYKQKEKTVSYLEEQVKQFSEQKDVAEKSTEQLRKDHAKISNRLDLLKKENETLHN
DIAKNSNSYEEYLKENGKLSERLNILQEKYNTLQNVKSNSNEHIDSIKRQCEELNVKL
KESTKKILSLEDELNEYANIVQDKTREANTLRRLVSDSQTDDSSKQKELENKLAYLTD
EKNKLEAELDLQTSRKATELQEWKHTVTELKSEIHALKLREEGLKSEVDALKHVNNDI
KRKTQATSDDSDQLEQITSNLKLSLSKADEKNFELQSANEKLLNLNNELNKKFDRLLK
NYRSLSSQLNALKERQYSDKSGRVSRSGSIGTLANANIDSSPANNSNPTKLEKIRSSS
SLELDSEKNEKIAYIKNVLLGFLEHKEQRNQLLPVISMLLQLDSTDEKRLVMSLK"
gene complement(752224..756993)
/gene="CDC25"
/locus_tag="YLR310C"
/gene_synonym="CTN1"
/db_xref="GeneID:851019"
mRNA complement(752224..756993)
/gene="CDC25"
/locus_tag="YLR310C"
/gene_synonym="CTN1"
/product="Cdc25p"
/transcript_id="NM_001182198.1"
/db_xref="GI:296146840"
/db_xref="GeneID:851019"
CDS complement(752224..756993)
/gene="CDC25"
/locus_tag="YLR310C"
/gene_synonym="CTN1"
/note="Membrane bound guanine nucleotide exchange factor
(GEF or GDP-release factor); indirectly regulates
adenylate cyclase through activation of Ras1p and Ras2p by
stimulating the exchange of GDP for GTP; required for
progression through G1"
/codon_start=1
/product="Cdc25p"
/protein_id="NP_013413.1"
/db_xref="GI:6323341"
/db_xref="SGD:S000004301"
/db_xref="GeneID:851019"
/translation="MSDTNTSIPNTSSAREAGNASQTPSISSSSNTSTTTNTESSSAS
LSSSPSTSELTSIRPIGIVVAAYDFNYPIKKDSSSQLLSVQQGETIYILNKNSSGWWD
GLVIDDSNGKVNRGWFPQNFGRPLRDSHLRKHSHPMKKYSSSKSSRRSSLNSLGNSAY
LHVPRNPSKSRRGSSTLSASLSNAHNAETSSGHNNTVSMNNSPFSAPNDASHITPQSS
NFNSNASLSQDMTKSADGSSEMNTNAIMNNNETNLQTSGEKAGPPLVAEETIKILPLE
EIEMIINGIRSNIASTWSPIPLITKTSDYKLVYYNKDLDIYCSELPLISNSIMESDDI
CDSEPKFPPNDHLVNLYTRDLRKNANIEDSSTRSKQSESEQNRSSLLMEKQDSKETDG
NNNSINDDDNNNENNKNEFNEAGPSSLNSLSAPDLTQNIQSRVVAPSRSSILAKSDIF
YHYSRDIKLWTELQDLTVYYTKTAHKMFLKENRLNFTKYFDLISDSIVFTQLGCRLMQ
HEIKAKSCSKEIKKIFKGLISSLSRISINSHLYFDSAFHRKKMDTMNDKDNDNQENNC
SRTEGDDGKIEVDSVHDLVSVPLSGKRNVSTSTTDTLTPMRSSFSTVNENDMENFSVL
GPRNSVNSVVTPRTSIQNSTLEDFSPSNKNFKSAKSIYEMVDVEFSKFLRHVQLLYFV
LQSSVFSDDNTLPQLLPRFFKGSFSGGSWTNPFSTFITDEFGNATKNKAVTSNEVTAS
SSKNSSISRIPPKMADAIASASGYSANSETNSQIDLKASSAASGSVFTPFNRPSHNRT
FSRARVSKRKKKYPLTVDTLNTMKKKSSQIFEKLNNATGEHLKIISKPKSRIRNLEIN
SSTYEQINQNVLLLEILENLDLSIFINLKNLIKTPSILLDLESEEFLVHAMSSVSSVL
TEFFDIKQAFHDIVIRLIMTTQQTTLDDPYLFSSMRSNFPVGHHEPFKNISNTPLVKG
PFHKKNEQLALSLFHVLVSQDVEFNNLEFLNNSDDFKDACEKYVEISNLACIIVDQLI
EERENLLNYAARMMKNNLTAELLKGEQEKWFDIYSEDYSDDDSENDEAIIDDELGSED
YIERKAANIEKNLPWFLTSDYETSLVYDSRGKIRGGTKEALIEHLTSHELVDAAFNVT
MLITFRSILTTREFFYALIYRYNLYPPEGLSYDDYNIWIEKKSNPIKCRVVNIMRTFL
TQYWTRNYYEPGIPLILNFAKMVVSEKIPGAEDLLQKINEKLINENEKEPVDPKQQDS
VSAVVQTTKRDNKSPIHMSSSSLPSSASSAFFRLKKLKLLDIDPYTYATQLTVLEHDL
YLRITMFECLDRAWGTKYCNMGGSPNITKFIANANTLTNFVSHTIVKQADVKTRSKLT
QYFVTVAQHCKELNNFSSMTAIVSALYSSPIYRLKKTWDLVSTESKDLLKNLNNLMDS
KRNFVKYRELLRSVTDVACVPFFGVYLSDLTFTFVGNPDFLHNSTNIINFSKRTKIAN
IVEEIISFKRFHYKLKRLDDIQTVIEASLENVPHIEKQYQLSLQVEPRSGNTKGSTHA
SSASGTKTAKFLSEFTDDKNGNFLKLGKKKPPSRLFR"
gene complement(757637..758833)
/locus_tag="YLR312C"
/db_xref="GeneID:851021"
mRNA complement(757637..758833)
/locus_tag="YLR312C"
/product="hypothetical protein"
/transcript_id="NM_001182200.1"
/db_xref="GI:296146841"
/db_xref="GeneID:851021"
CDS complement(757637..758833)
/locus_tag="YLR312C"
/codon_start=1
/product="hypothetical protein"
/protein_id="NP_013415.1"
/db_xref="GI:6323343"
/db_xref="SGD:S000004303"
/db_xref="GeneID:851021"
/translation="MSEEDDHWNLVRLRRLRKGREGEEQSSKSEISLDSLHESSFAGE
DDEDFDADVLSNTSSEESAQMNRIYDFRTSNEFSNAGVNIDQTGVPTISESFDTLSGS
NVGGTVLPSMEGSKLKDSTIRNSSTLSDHIIDKSEGKSAKLKMWHVIMLSSLLSMTFS
YLALEYSLTGDVLAGFKSQQSLRNNERKLLYGNIDFVDKKSYDSSSDSLSQWAPSGKY
YVDFDNHIAYPLKDDDLMGWRRYKTDLVILWYTTKARMKDGWHKRINKINGGRIKLHL
FLKNSFKSAQESLRVLHKEQKRRWKRLFVLLHNKYRQFSPHIKRYFDHSCQKAKQCWS
GSRLQLRKLRFKSMKPFRVFQFKVRKDTNWFVKQLKRFGLKLQHSRMYKAMSECRKKN
YFKCKH"
gene 759480..760241
/gene="MRPL15"
/locus_tag="YLR312W-A"
/db_xref="GeneID:851022"
mRNA 759480..760241
/gene="MRPL15"
/locus_tag="YLR312W-A"
/product="mitochondrial 54S ribosomal protein YmL15"
/transcript_id="NM_001182201.1"
/db_xref="GI:296146842"
/db_xref="GeneID:851022"
CDS 759480..760241
/gene="MRPL15"
/locus_tag="YLR312W-A"
/note="Mitochondrial ribosomal protein of the large
subunit"
/codon_start=1
/product="mitochondrial 54S ribosomal protein YmL15"
/protein_id="NP_013416.2"
/db_xref="GI:116006497"
/db_xref="SGD:S000004304"
/db_xref="GeneID:851022"
/translation="MENSMMFISRSLRRPVTALNCNLQSVRTVIYLHKGPRINGLRRD
PESYLRNPSGVLFTEVNAKECQDKVRSILQLPKYGINLSNELILQCLTHKSFAHGSKP
YNEKLNLLGAQFLKLQTCIHSLKNGSPAESCENGQLSLQFSNLGTKFAKELTSKNTAC
TFVKLHNLDPFIFWKMRDPIKDGHINGETTIFASVLNAFIGAILSTNGSEKAAKFIQG
SLLDKEDLHSLVNIANENVASAKAKISDKENKAFL"
gene complement(760750..762342)
/gene="SPH1"
/locus_tag="YLR313C"
/gene_synonym="YLR312C-B"
/db_xref="GeneID:851023"
mRNA complement(760750..762342)
/gene="SPH1"
/locus_tag="YLR313C"
/gene_synonym="YLR312C-B"
/product="Sph1p"
/transcript_id="NM_001182202.2"
/db_xref="GI:330443673"
/db_xref="GeneID:851023"
CDS complement(760750..762342)
/gene="SPH1"
/locus_tag="YLR313C"
/gene_synonym="YLR312C-B"
/note="Protein involved in shmoo formation and bipolar bud
site selection; homologous to Spa2p, localizes to sites of
polarized growth in a cell cycle dependent- and
Spa2p-dependent manner, interacts with MAPKKs Mkk1p,
Mkk2p, and Ste7p"
/codon_start=1
/product="Sph1p"
/protein_id="NP_013417.3"
/db_xref="GI:330443674"
/db_xref="SGD:S000004305"
/db_xref="GeneID:851023"
/translation="MISSELTNDQIIDLISDYKNFKRIIEASVPEDDRRRNQNRQNRN
KDLTKLSNVQFWQLTTDVNDELMKRLTDSGADASLNDLDLKRGKAQSKLSRLKDAKFH
KLILDIFTEIERRNLHHLDMGTHNNGLDEGDLNFYLNDTLFESFKINDDFMSVNGIIS
IEVFRELKTQFTLYFQNTLHRIDPVDTTTTRLPILLETIIKIAKLIGDLLPVLSSVSL
QSSLENEIVYLKSALSHAITSTRYFLTYGDLIPRIVAQSSISEVIFAFCNIAQIVKIK
STSRDDISRNEGELSDIEAGMKPLKIIEKVKNEKNGKDISSLGDSGSTAVSFPSSGKP
ITKKSDMPVVVASPSISIIEKSESSIRESGKVRNNTSGETNLASVSPLKNTKNSSRIT
SEPSPREGLPLKVVSNSRSPSPQGNTLPLIGKFRQDYQASPPKKVITKPVAETAKPYA
NIPPAADVLYSPTVTKMRKFREKVQKFAPNSGLGLRISTSEENLNNSDVNSTTHNANI
NNLVEFVESKSMVVLPMAGRAF"
gene complement(762575..764137)
/gene="CDC3"
/locus_tag="YLR314C"
/db_xref="GeneID:851024"
mRNA complement(762575..764137)
/gene="CDC3"
/locus_tag="YLR314C"
/product="septin CDC3"
/transcript_id="NM_001182203.2"
/db_xref="GI:330443675"
/db_xref="GeneID:851024"
CDS complement(762575..764137)
/gene="CDC3"
/locus_tag="YLR314C"
/note="Component of the septin ring that is required for
cytokinesis; septins are GTP-binding proteins that
assemble with other septins into rod-like complexes that
can associate with other rods to form filament polymers;
septin rings at the mother-bud neck act as scaffolds for
recruiting factors needed for cell division and as
barriers to prevent diffusion of specific proteins between
mother and daughter cells"
/codon_start=1
/product="septin CDC3"
/protein_id="NP_013418.2"
/db_xref="GI:330443676"
/db_xref="SGD:S000004306"
/db_xref="GeneID:851024"
/translation="MSLKEEQVSIKQDPEQEERQHDQFNDVQIKQESQDHDGVDSQYT
NGTQNDDSERFEAAESDVKVEPGLGMGITSSQSEKGQVLPDQPEIKFIRRQINGYVGF
ANLPKQWHRRSIKNGFSFNLLCVGPDGIGKTTLMKTLFNNDDIEANLVKDYEEELAND
QEEEEGQGEGHENQSQEQRHKVKIKSYESVIEENGVKLNLNVIDTEGFGDFLNNDQKS
WDPIIKEIDSRFDQYLDAENKINRHSINDKRIHACLYFIEPTGHYLKPLDLKFMQSVY
EKCNLIPVIAKSDILTDEEILSFKKTIMNQLIQSNIELFKPPIYSNDDAENSHLSERL
FSSLPYAVIGSNDIVENYSGNQVRGRSYPWGVIEVDNDNHSDFNLLKNLLIKQFMEEL
KERTSKILYENYRSSKLAKLGIKQDNSVFKEFDPISKQQEEKTLHEAKLAKLEIEMKT
VFQQKVSEKEKKLQKSETELFARHKEMKEKLTKQLKALEDKKKQLELSINSASPNVNH
SPVPTKKKGFLR"
gene 764808..765269
/gene="NKP2"
/locus_tag="YLR315W"
/db_xref="GeneID:851025"
mRNA 764808..765269
/gene="NKP2"
/locus_tag="YLR315W"
/product="Nkp2p"
/transcript_id="NM_001182204.1"
/db_xref="GI:296146845"
/db_xref="GeneID:851025"
CDS 764808..765269
/gene="NKP2"
/locus_tag="YLR315W"
/note="Central kinetochore protein and subunit of the
Ctf19 complex; mutants have elevated rates of chromosome
loss; orthologous to fission yeast kinetochore protein
cnl2"
/codon_start=1
/product="Nkp2p"
/protein_id="NP_013419.1"
/db_xref="GI:6323347"
/db_xref="SGD:S000004307"
/db_xref="GeneID:851025"
/translation="MNSEQLLHNYVSDSLLTTLISFQEFKQQLQSYTSDEQQLQHWYE
LLQARDARVTSELEARIKQFFITLRSRLLRFLESEQLSHSLSLETLIDALYKINDLLQ
QRLQILDDAIQEKTSELAEFENMVRSPSAGDNAIPGLLQIIQSYINLLEEN"
gene complement(765266..766358)
/gene="TAD3"
/locus_tag="YLR316C"
/db_xref="GeneID:851027"
mRNA complement(join(765266..766073,766130..766181,
766250..766358))
/gene="TAD3"
/locus_tag="YLR316C"
/product="Tad3p"
/transcript_id="NM_001182205.1"
/db_xref="GI:296146846"
/db_xref="GeneID:851027"
CDS complement(join(765266..766073,766130..766181,
766250..766358))
/gene="TAD3"
/locus_tag="YLR316C"
/note="Subunit of tRNA-specific adenosine-34 deaminase,
forms a heterodimer with Tad2p that converts adenosine to
inosine at the wobble position of several tRNAs"
/codon_start=1
/product="Tad3p"
/protein_id="NP_013420.2"
/db_xref="GI:9755339"
/db_xref="SGD:S000004308"
/db_xref="GeneID:851027"
/translation="MVKKVNNPLKIDYQNGIIENRLLQIRNFKDVNTPKLINVWSIRI
DPRDSKKVIELIRNDFQKNDPVSLRHLKRIRKDIETSTLEVVLCSKEYICDEGEINNK
LKSIWVGTKKYELSDDIEVPEFAPSTKELNNAWSVKYWPLIWNGNPNDQILNDYKIDM
QEVRNELSRASTLSVKMATAGKQFPMVSVFVDPSRKKDKVVAEDGRNCENSLPIDHSV
MVGIRAVGERLREGVDEDANSYLCLDYDVYLTHEPCSMCSMALIHSRVRRVVFLTEMQ
RTGSLKLTSGDGYCMNDNKQLNSTYEAFQWIGEEYPVGQVDRDVCC"
gene 766542..769196
/gene="EST2"
/locus_tag="YLR318W"
/db_xref="GeneID:851028"
mRNA 766542..769196
/gene="EST2"
/locus_tag="YLR318W"
/product="Est2p"
/transcript_id="NM_001182207.2"
/db_xref="GI:330443677"
/db_xref="GeneID:851028"
CDS 766542..769196
/gene="EST2"
/locus_tag="YLR318W"
/EC_number="2.7.7.49"
/note="Reverse transcriptase subunit of the telomerase
holoenzyme, essential for telomerase core catalytic
activity, involved in other aspects of telomerase assembly
and function; mutations in human homolog are associated
with aplastic anemia"
/codon_start=1
/product="Est2p"
/protein_id="NP_013422.2"
/db_xref="GI:330443678"
/db_xref="SGD:S000004310"
/db_xref="GeneID:851028"
/translation="MKILFEFIQDKLDIDLQTNSTYKENLKCGHFNGLDEILTTCFAL
PNSRKIALPCLPGDLSHKAVIDHCIIYLLTGELYNNVLTFGYKIARNEDVNNSLFCHS
ANVNVTLLKGAAWKMFHSLVGTYAFVDLLINYTVIQFNGQFFTQIVGNRCNEPHLPPK
WAQRSSSSSATAAQIKQLTEPVTNKQFLHKLNINSSSFFPYSKILPSSSSIKKLTDLR
EAIFPTNLVKIPQRLKVRINLTLQKLLKRHKRLNYVSILNSICPPLEGTVLDLSHLSR
QSPKERVLKFIIVILQKLLPQEMFGSKKNKGKIIKNLNLLLSLPLNGYLPFDSLLKKL
RLKDFRWLFISDIWFTKHNFENLNQLAICFISWLFRQLIPKIIQTFFYCTEISSTVTI
VYFRHDTWNKLITPFIVEYFKTYLVENNVCRNHNSYTLSNFNHSKMRIIPKKSNNEFR
IIAIPCRGADEEEFTIYKENHKNAIQPTQKILEYLRNKRPTSFTKIYSPTQIADRIKE
FKQRLLKKFNNVLPELYFMKFDVKSCYDSIPRMECMRILKDALKNENGFFVRSQYFFN
TNTGVLKLFNVVNASRVPKPYELYIDNVRTVHLSNQDVINVVEMEIFKTALWVEDKCY
IREDGLFQGSSLSAPIVDLVYDDLLEFYSEFKASPSQDTLILKLADDFLIISTDQQQV
INIKKLAMGGFQKYNAKANRDKILAVSSQSDDDTVIQFCAMHIFVKELEVWKHSSTMN
NFHIRSKSSKGIFRSLIALFNTRISYKTIDTNLNSTNTVLMQIDHVVKNISECYKSAF
KDLSINVTQNMQFHSFLQRIIEMTVSGCPITKCDPLIEYEVRFTILNGFLESLSSNTS
KFKDNIILLRKEIQHLQAYIYIYIHIVN"
gene complement(769318..771684)
/gene="BUD6"
/locus_tag="YLR319C"
/gene_synonym="AIP3"
/db_xref="GeneID:851029"
mRNA complement(769318..771684)
/gene="BUD6"
/locus_tag="YLR319C"
/gene_synonym="AIP3"
/product="Bud6p"
/transcript_id="NM_001182208.1"
/db_xref="GI:296146848"
/db_xref="GeneID:851029"
CDS complement(769318..771684)
/gene="BUD6"
/locus_tag="YLR319C"
/gene_synonym="AIP3"
/note="Actin- and formin-interacting protein; stimulates
actin cable nucleation by recruiting actin monomers to
Bni1p; involved in polarized cell growth; isolated as
bipolar budding mutant; potential Cdc28p substrate"
/codon_start=1
/product="Bud6p"
/protein_id="NP_013423.1"
/db_xref="GI:6323351"
/db_xref="SGD:S000004311"
/db_xref="GeneID:851029"
/translation="MKMAVDDPTYGTPKIKRTASSSSSIETTVTKLLMSTKHLLQVLT
QWSKGTTSGRLVSDAYVQLGNDFKVVSKFFMHAKVDMSDVGDVPMALRRVLEVTLREP
PSDETLNKHLPKIREIIVTLLDKLKVKQAILKNMQQEHRISVKSHHQQNPSFTSNLSL
GSEGTREGTPLSSRKSSIVRDQRQSDSVENSYGEKVNSTSTGTPSAQSAEATLTKPRT
NIKQNLKSNNAPNASDDDDALSQLKKGTNLQRRASKRYSAYHMAKLTNQSTTEAAAAA
GLMTTPSPSMLHLEETVRKSKLYGNNNNDDDRNINSAENKGKSIDDVSKASPLAKTPL
PIENVRASPRRLSSVVTTSPDKAMNGTCPVFLRIGDKTKKCHVQLPTTKNALRLLFIE
RFAYSPGANSFPDIYIMDPQYGVFYELEELNLLDIKEGFVIELKLEENPNNTIKEFID
TVKMEISNSQNDIIRHLKEMSFGSAISGKQTEVLPQPGLEANKHDLVGQNKKDDDKTI
KDIQYELGKIKQVHNINRSNINETIFNILRKVDNFKSLSFSAKNSSNRMYMEKSQTEL
GDLSDTLLSKVDDLQDVIEIMRKDVAERRSQPAKKKLETVSKDLENAQADVLKLQEFI
DTEKPHWKKTWEAELDKVCEEQQFLTLQEELILDLKEDLGKALETFDLIKLCCEEQEK
NPSRSKSNPILPIMRPGTFNQVREQVMVAVQSLNPDHDSRVEAIDKAEKMWEMERKLK
ASNEFDDELENFVGNSNLKKSGGFEEVERIRKQKDEANLRAYFGPGFT"
gene 771940..776304
/gene="MMS22"
/locus_tag="YLR320W"
/gene_synonym="SLM2"
/db_xref="GeneID:851030"
mRNA 771940..776304
/gene="MMS22"
/locus_tag="YLR320W"
/gene_synonym="SLM2"
/product="Mms22p"
/transcript_id="NM_001182209.1"
/db_xref="GI:296146849"
/db_xref="GeneID:851030"
CDS 771940..776304
/gene="MMS22"
/locus_tag="YLR320W"
/gene_synonym="SLM2"
/note="Subunit of an E3 ubiquitin ligase complex involved
in replication repair; stabilizes protein components of
the replication fork, such as the fork-pausing complex and
leading strand polymerase, preventing fork collapse and
promoting efficient recovery during replication stress;
required for accurate meiotic chromosome segregation"
/codon_start=1
/product="Mms22p"
/protein_id="NP_013424.1"
/db_xref="GI:6323352"
/db_xref="SGD:S000004312"
/db_xref="GeneID:851030"
/translation="MDVDEPNPIVISDSEATDEEISIIYEPEFNENYLWAEENVQEAS
RSQKIVTERLSLDSTAGESCTPSVVTDTQVTTGLRWSLRKRKAIQKMPYSLERIKHRQ
LLEGYDISSFDSISNQLTLPKNASTVIHSNDILLTKRTGKPLDEQKDVTIDSIKPENS
SVQSQRYDSDEEIPKKRHRTFKDLDQDIVFQSGDSTEDEQDLASTNLQNTQNDEVIFR
GRVLNVRTGYRGVLPRVAWEKSLQKQQSSKVTKRKTQLLNHKGVAKRKMNRSAHIEDE
EQNLLNDLIAPDDELDIEENAPPDIYLGNLPEDREANEKELKELQEYYESKYSEDAQS
AGTSGFNLNEEYRNEPVYELEYDGPGSCISHVSYKDQPIIYLNSRHSDSGFSEQYNIS
AEDNQSVISLDAAEEHNDGIIDKMLVKPKRIKATNDANFLNTKSKRVRRYKYKYRNSC
LAPSTKAIKVGKRSAHKSHLAANNPVSFVSKKNHVIDDYFFEELESQSLEQDDSSSLK
PQKKRRKKKAPIYSSFSADLESRRKPVFNTVVEVPTNRYAFTKPNVRNRDSINHDMEF
EEEDSNQELGPIMVVLDSILLKKPFEPPNFFKIQLSDKSFLLSKLNPADIATSLQKIF
RVIIDKGITDTELVHFNESLIAFLVHLDMPELFDLIGEFHREFRSKVNSLRKKAKPIH
FFQIAACQLMFLEISRYNKISAAAKFDMDVKLLDHIVSFFKLLSVCYDSVMKNPMQYL
YTSYYILSAVVDVIHKKEALWDLFQKHPFSPHISLLLVNIFPTKVCRWQVLRLDSEFQ
PLSSAFRFINYCIETCNWNVTNSLILSLDRIFKRRRFSDFEEESDLSQNNKIIYPPTN
QLTSRLMFNRYLHLLTLCELSSSDTQRVIPMGDISMNDSLSVLKNRLNLLIVLATRFD
LNLEKRFQELTRPLYSKEYLNLHTQNTVRTITTLIMQASLSFLEISRIKNHPFSGKFI
ASLFDKLVLQQPSISGVTENFLKEFTNLVSKMKRKSVSMLKFLYPSLVAMSQENIFES
SFFLLLQVYLKSLDVLGPTWVQNYLFQFIKSKAQENERWIECYCQIGKFLVDSGIFTW
WTFFTYNGLDAALHFQLAFHSLIIDFCDTDSFELLKKPLYSIASDLLLISKDDAFYHF
LSNLLKRAHIIVADLKPVSDENELLRLAYIFSKALKKNAYQDLLAVFLSLAKKHYDEG
DISRNFLAKYLEFLNKNCLTELRNNQLFISLRRELGISSDEDEKCAFWDSFNEAGDIL
SKAAFVETGIVQACCTGNEIDGYLDNLSTLFTSTMLESPFAFFSDLVIAHIFENRPFF
DVNIKNFLLSHFIDLFNKVLKMKFEQVSPDEFAELCKVYRALCIECATDDTFNSNSDL
IAAKDAFLVSVLRIADGFWEHDKLLQLRMLDSNMNIPNQIPHTTLQSSLSAIVIKIIE
SNIGKIEASEPFKTFKNT"
gene complement(776584..777864)
/gene="SFH1"
/locus_tag="YLR321C"
/db_xref="GeneID:851032"
mRNA complement(776584..777864)
/gene="SFH1"
/locus_tag="YLR321C"
/product="Sfh1p"
/transcript_id="NM_001182210.1"
/db_xref="GI:296146850"
/db_xref="GeneID:851032"
CDS complement(776584..777864)
/gene="SFH1"
/locus_tag="YLR321C"
/note="Component of the RSC chromatin remodeling complex;
essential gene required for cell cycle progression and
maintenance of proper ploidy; phosphorylated in the G1
phase of the cell cycle; Snf5p paralog"
/codon_start=1
/product="Sfh1p"
/protein_id="NP_013425.1"
/db_xref="GI:6323354"
/db_xref="SGD:S000004313"
/db_xref="GeneID:851032"
/translation="MSHQNQLIPQAYISNFHNRLTNEDDGIPIFTMAQQTRQHKRAKV
VNYAEYDNDLFDEFNMNGSNFNNADTHYKDNAVSHENTPALTNGVTMDGSEYNVLENM
NGADSIISNNKYDAGSNMVVESLSGLNSNNNASNGPSNKAQAQDIGNAVLPDLQDQHH
NPFNILRYPKIRDTFINGKVVSPYRLNTDQETKANANSGEAIMIPITLDIEHMGHTIK
DQFLWNYNDDSISPEEFASIYCKDLDMTSATLQTQIANIIKEQLKDLENIAATEIMSD
LHVIINLTCNLQDRFFEDNFQWNLNDKSLTPERFATSIVQDLGLTREFIPLISQSLHE
TILKIKKDWVDGHLIQDHVPNDAAFGYLSGIRLDIDELGSNWCPRVEILTKEEIQKRE
IEKERNLRRLKRETDRLSRRGRRRLDDLETTMRM"
gene complement(778173..778952)
/gene="CWC24"
/locus_tag="YLR323C"
/db_xref="GeneID:851033"
mRNA complement(778173..778952)
/gene="CWC24"
/locus_tag="YLR323C"
/product="Cwc24p"
/transcript_id="NM_001182212.1"
/db_xref="GI:296146851"
/db_xref="GeneID:851033"
CDS complement(778173..778952)
/gene="CWC24"
/locus_tag="YLR323C"
/note="Spliceosome assembly factor, essential for the
first step of splicing; component of the pre-catalytic
spliceosome complex containing Cef1p; has similarity to S.
pombe Cwf24p"
/codon_start=1
/product="Cwc24p"
/protein_id="NP_013427.1"
/db_xref="GI:6323355"
/db_xref="SGD:S000004315"
/db_xref="GeneID:851033"
/translation="MFRKRLVNKSSSDEKNQKKRQKINFSEEKLVASDEEKGSSDLMS
LAKSGNSRTLQLSHENEGKLQKKGEDLDKYTLTVNDDSTKEDLLNFERKELAEKAKKR
RPSDDNELVLNMSGKNKRLTKQINQPTNIRTTVLMDFQPDVCKDYKQTGYCGYGDSCK
FLHSRDDFKTGWKLNQEWNADKEDSKAVTLDLEKIPFKCTLCKEDYKSPVVTNCGHYF
CGSCFAKDMKKGTKCFICHKETHGSAKVASDLQKMLNKRKS"
gene 779215..780786
/gene="PEX30"
/locus_tag="YLR324W"
/db_xref="GeneID:851034"
mRNA 779215..780786
/gene="PEX30"
/locus_tag="YLR324W"
/product="Pex30p"
/transcript_id="NM_001182213.1"
/db_xref="GI:296146852"
/db_xref="GeneID:851034"
CDS 779215..780786
/gene="PEX30"
/locus_tag="YLR324W"
/note="Peroxisomal integral membrane protein, involved in
negative regulation of peroxisome number; partially
functionally redundant with Pex31p; genetic interactions
suggest action at a step downstream of steps mediated by
Pex28p and Pex29p"
/codon_start=1
/product="Pex30p"
/protein_id="NP_013428.1"
/db_xref="GI:6323356"
/db_xref="SGD:S000004316"
/db_xref="GeneID:851034"
/translation="MSGNTTNVHETRAKFAETLQPRIGGNTTKVIRAALEKNEAESGV
SEDNDNGSLEKVNVATSPLLTSTPPTISKALVKLYPYLILIDEFLNVVTWTGKNIWSS
VLMLCLFITTVEYFETLVKYFGHLAIIAILWGYSLLDNYIEGTLSSSPTLEDIALLMN
RVSLKSDILLSPMVNLGTQDIQRLLYTTVILSPIYVMITWLLLPPRSLMLMVGMFLLT
YHSPWSKVARRLLWKFKIVRLLVFYVTGLDLGGINKDQGIFATVQKQVKKLASTENSN
GVLSDSKPIRFTYVLYENQRRWLGIGWKPSMLSYERTPWTDEFLNEAPSPENFHLPEE
TNTMVWRWVDKTWRLDMTNDGAIQVPNSKARTSADPSPDEGFIYYDNTWKKPSKEDSF
SKYTRRRRWVRTAELVKTSDFDESVINSNRNSAIEQKVEENSTNGLTAEQELGSNKQE
KDNAKKVGEPTTEETKEFAEASNINEGEFERISSTDEEVLKSRARDRLAKVLDDTEEK
EQSNPTIGRDSKKAV"
gene complement(781143..781379)
/gene="RPL38"
/locus_tag="YLR325C"
/db_xref="GeneID:851035"
mRNA complement(781143..781379)
/gene="RPL38"
/locus_tag="YLR325C"
/product="ribosomal 60S subunit protein L38"
/transcript_id="NM_001182214.1"
/db_xref="GI:296146853"
/db_xref="GeneID:851035"
CDS complement(781143..781379)
/gene="RPL38"
/locus_tag="YLR325C"
/note="Ribosomal 60S subunit protein L38; homologous to
mammalian ribosomal protein L38, no bacterial homolog"
/codon_start=1
/product="ribosomal 60S subunit protein L38"
/protein_id="NP_013429.1"
/db_xref="GI:6323357"
/db_xref="SGD:S000004317"
/db_xref="GeneID:851035"
/translation="MAREITDIKQFLELTRRADVKTATVKINKKLNKAGKPFRQTKFK
VRGSSSLYTLVINDAGKAKKLIQSLPPTLKVNRL"
gene 782174..782896
/locus_tag="YLR326W"
/db_xref="GeneID:851036"
mRNA 782174..782896
/locus_tag="YLR326W"
/product="hypothetical protein"
/transcript_id="NM_001182215.1"
/db_xref="GI:296146854"
/db_xref="GeneID:851036"
CDS 782174..782896
/locus_tag="YLR326W"
/note="hypothetical protein, predicted to be
palmitoylated"
/codon_start=1
/product="hypothetical protein"
/protein_id="NP_013430.1"
/db_xref="GI:6323358"
/db_xref="SGD:S000004318"
/db_xref="GeneID:851036"
/translation="MSGFIKSTLLGLGQDYLEDQYQEFAEQHFQPTRDPFYETNKDGK
KHRRRLPYYCTKDESKAWKKVQNKAWLHDKSLCGCCCWTNTIGWAPLLALLPVIGPLL
MYWVHDKLIELADDRYKLPAEIKVKMHGNIVIDLLISLVPILGSVFAWLHACSTRNAA
IVYNFVGKRALERKQAELMHQKEENEKHSNANTAPPVVGGNKNVNGNRNNSKMYNRPP
VTAPPAPAYTRSTNGRPQRGYR"
gene complement(783127..783387)
/gene="TMA10"
/locus_tag="YLR327C"
/gene_synonym="SFL2"
/db_xref="GeneID:851037"
mRNA complement(783127..783387)
/gene="TMA10"
/locus_tag="YLR327C"
/gene_synonym="SFL2"
/product="Tma10p"
/transcript_id="NM_001182216.1"
/db_xref="GI:296146855"
/db_xref="GeneID:851037"
CDS complement(783127..783387)
/gene="TMA10"
/locus_tag="YLR327C"
/gene_synonym="SFL2"
/note="hypothetical protein that associates with
ribosomes; putative homolog of the F1F0-ATPase synthase
regulator Stf2p; protein abundance increases in response
to DNA replication stress"
/codon_start=1
/product="Tma10p"
/protein_id="NP_013431.1"
/db_xref="GI:6323359"
/db_xref="SGD:S000004319"
/db_xref="GeneID:851037"
/translation="MTRTSKWTVHEAKSNPKYFTHNGNFGESPNHVKRGGYGKGNWGK
PGDEINDLIDSGEIKTVFNKTRRGSNSQNNERRLSDLQQYHI"
gene 784354..784453
/locus_tag="tX(XXX)L"
/db_xref="GeneID:851038"
tRNA join(784354..784389,784410..784453)
/locus_tag="tX(XXX)L"
/product="tRNA-Ser"
/note="tRNA of undetermined specificity, predicted by
tRNAscan-SE analysis; very similar to serine tRNAs"
/db_xref="SGD:S000006732"
/db_xref="GeneID:851038"
gene 784913..786118
/gene="NMA1"
/locus_tag="YLR328W"
/db_xref="GeneID:851039"
mRNA 784913..786118
/gene="NMA1"
/locus_tag="YLR328W"
/product="nicotinamide-nucleotide adenylyltransferase
NMA1"
/transcript_id="NM_001182217.1"
/db_xref="GI:296146856"
/db_xref="GeneID:851039"
CDS 784913..786118
/gene="NMA1"
/locus_tag="YLR328W"
/EC_number="2.7.7.18"
/EC_number="2.7.7.1"
/note="Nicotinic acid mononucleotide adenylyltransferase;
catalyzes the transfer of the adenylyl moiety of ATP to
nicotinamide mononucleotide to form NAD; involved in
pathways of NAD biosynthesis, including the de novo,
NAD(+) salvage, and nicotinamide riboside salvage
pathways; NMA1 has a paralog, NMA2, that arose from the
whole genome duplication"
/codon_start=1
/product="nicotinamide-nucleotide adenylyltransferase
NMA1"
/protein_id="NP_013432.1"
/db_xref="GI:6323360"
/db_xref="SGD:S000004320"
/db_xref="GeneID:851039"
/translation="MDPTRAPDFKPPSADEELIPPPDPESKIPKSIPIIPYVLADANS
SIDAPFNIKRKKKHPKHHHHHHHSRKEGNDKKHQHIPLNQDDFQPLSAEVSSEDDDAD
FRSKERYGSDSTTESETRGVQKYQIADLEEVPHGIVRQARTLEDYEFPSHRLSKKLLD
PNKLPLVIVACGSFSPITYLHLRMFEMALDAISEQTRFEVIGGYYSPVSDNYQKQGLA
PSYHRVRMCELACERTSSWLMVDAWESLQPSYTRTAKVLDHFNHEINIKRGGVATVTG
EKIGVKIMLLAGGDLIESMGEPNVWADADLHHILGNYGCLIVERTGSDVRSFLLSHDI
MYEHRRNILIIKQLIYNDISSTKVRLFIRRAMSVQYLLPNSVIRYIQEHRLYVDQTEP
VKQVLGNKE"
gene 786442..787333
/gene="REC102"
/locus_tag="YLR329W"
/db_xref="GeneID:851040"
mRNA join(786442..786615,786713..787333)
/gene="REC102"
/locus_tag="YLR329W"
/product="Rec102p"
/transcript_id="NM_001182218.1"
/db_xref="GI:296146857"
/db_xref="GeneID:851040"
CDS join(786442..786615,786713..787333)
/gene="REC102"
/locus_tag="YLR329W"
/note="Protein involved in early stages of meiotic
recombination; required for chromosome synapsis; forms a
complex with Rec104p and Spo11p necessary during the
initiation of recombination"
/codon_start=1
/product="Rec102p"
/protein_id="NP_013433.2"
/db_xref="GI:85666120"
/db_xref="SGD:S000004321"
/db_xref="GeneID:851040"
/translation="MARDITFLTVFLESCGAVNNDEAGKLLSAWTSTVRIEGPESTDS
NSLYIPLLPPGMLKIKLNFKMNDRLVTEEQELFTKLREIVGSSIRFWEEQLFYQVQDV
STIENHVILSLKCTILTDAQISTFISKPRELHTHAKGYPEIYYLSELSTTVNFFSKEG
NYVEISQVIPHFNEYFSSLIVSQLEFEYPMVFSMISRLRLKWQQSSLAPISYALTSNS
VLLPIMLNMIAQDKSSTTAYQILCRRRGPPIQNFQIFSLPAVTYNK"
gene 787664..789679
/gene="CHS5"
/locus_tag="YLR330W"
/gene_synonym="CAL3"
/db_xref="GeneID:851041"
mRNA 787664..789679
/gene="CHS5"
/locus_tag="YLR330W"
/gene_synonym="CAL3"
/product="Chs5p"
/transcript_id="NM_001182219.1"
/db_xref="GI:296146858"
/db_xref="GeneID:851041"
CDS 787664..789679
/gene="CHS5"
/locus_tag="YLR330W"
/gene_synonym="CAL3"
/note="Component of the exomer complex, which also
contains Csh6p, Bch1p, Bch2p, and Bud7p and is involved in
export of selected proteins, such as chitin synthase
Chs3p, from the Golgi to the plasma membrane"
/codon_start=1
/product="Chs5p"
/protein_id="NP_013434.1"
/db_xref="GI:6323362"
/db_xref="SGD:S000004322"
/db_xref="GeneID:851041"
/translation="MSSVDVLLTVGKLDASLALLTTQDHHVIEFPTVLLPENVKAGSI
IKMQVSQNLEEEKKQRNHFKSIQAKILEKYGTHKPESPVLKIVNVTQTSCVLAWDPLK
LGSAKLKSLILYRKGIRSMVIPNPFKVTTTKISGLSVDTPYEFQLKLITTSGTLWSEK
VILRTHKMTDMSGITVCLGPLDPLKEISDLQISQCLSHIGARPLQRHVAIDTTHFVCN
DLDNEESNEELIRAKHNNIPIVRPEWVRACEVEKRIVGVRGFYLDADQSILKNYTFPP
VNEEELSYSKENEPVAEVADENKMPEDTTDVEQVASPNDNESNPSEAKEQGEKSGHET
APVSPVEDPLHASTALENETTIETVNPSVRSLKSEPVGTPNIEENKADSSAEAVVEEP
NEAVAESSPNEEATGQKSEDTDTHSNEQADNGFVQTEEVAENNITTESAGENNEPADD
AAMEFGRPEAEIETPEVNESIEDANEPAEDSNEPVEDSNKPVKDSNKPVEDSNKPVED
SNKPVEDSNKPVEDANEPVEDTSEPVEDAGEPVQETNEFTTDIASPRHQEEDIELEAE
PKDATESVAVEPSNEDVKPEEKGSEAEDDINNVSKEAASGESTTHQKTEASASLESSA
VTEEQETTEAEVNTDDVLSTKEAKKNTGNSNSNKKKNKKNKKKGKKK"
gene 790676..791806
/gene="MID2"
/locus_tag="YLR332W"
/gene_synonym="KAI1"
/db_xref="GeneID:851042"
mRNA 790676..791806
/gene="MID2"
/locus_tag="YLR332W"
/gene_synonym="KAI1"
/product="Mid2p"
/transcript_id="NM_001182221.1"
/db_xref="GI:296146859"
/db_xref="GeneID:851042"
CDS 790676..791806
/gene="MID2"
/locus_tag="YLR332W"
/gene_synonym="KAI1"
/note="O-glycosylated plasma membrane protein that acts as
a sensor for cell wall integrity signaling and activates
the pathway; interacts with Rom2p, a guanine nucleotide
exchange factor for Rho1p, and with cell integrity pathway
protein Zeo1p"
/codon_start=1
/product="Mid2p"
/protein_id="NP_013436.1"
/db_xref="GI:6323363"
/db_xref="SGD:S000004324"
/db_xref="GeneID:851042"
/translation="MLSFTTKNSFRLLLLILSCISTIRAQFFVQSSSSNSSAVSTARS
SVSRVSSSSSILSSSMVSSSSADSSSLTSSTSSRSLVSHTSSSTSIASISFTSFSFSS
DSSTSSSSSASSDSSSSSSFSISSTSATSESSTSSTQTSTSSSSSLSSTPSSSSSPST
ITSAPSTSSTPSTTAYNQGSTITSIINGKTILSNHYTTVTYTPSATADSSNKSKSSGL
SKKNRNIVIGCVVGIGVPLILVILALIYMFCIQSSRTDFIDSDGKVVTAYRANKFTKW
WYMLLGKKVSDEYHSDSPLGGSASSAGGLDLDEADDVMEQSSLFDVRIRDSDSVLPNA
NTADHNNTNSGGEPINSSVASNDIIEEKFYDEQGNELSPRNY"
LTR 793552..793870
/note="Ty3 LTR"
/db_xref="SGD:S000007097"
gene 793918..793989
/locus_tag="tD(GUC)L2"
/db_xref="GeneID:851044"
tRNA 793918..793989
/locus_tag="tD(GUC)L2"
/product="tRNA-Asp"
/note="Aspartate tRNA (tRNA-Asp), predicted by tRNAscan-SE
analysis"
/db_xref="SGD:S000006542"
/db_xref="GeneID:851044"
rep_origin 794021..794269
/note="ARS1226;
Autonomously Replicating Sequence"
/db_xref="SGD:S000118480"
gene complement(794486..794575)
/locus_tag="snR61"
/db_xref="GeneID:9164949"
ncRNA complement(794486..794575)
/locus_tag="snR61"
/ncRNA_class="snoRNA"
/product="SNR61"
/note="C/D box small nucleolar RNA (snoRNA), guides
2'-O-methylation of large subunit (LSU) rRNA at position
A1133"
/db_xref="SGD:S000006452"
/db_xref="GeneID:9164949"
gene complement(794697..794794)
/locus_tag="snR55"
/db_xref="GeneID:9164944"
ncRNA complement(794697..794794)
/locus_tag="snR55"
/ncRNA_class="snoRNA"
/product="SNR55"
/note="C/D box small nucleolar RNA (snoRNA), predicted to
guide 2'-O-methylation of small subunit (SSU) rRNA at
position U1269"
/db_xref="SGD:S000006446"
/db_xref="GeneID:9164944"
gene complement(794937..795024)
/locus_tag="snR57"
/db_xref="GeneID:9164947"
ncRNA complement(794937..795024)
/locus_tag="snR57"
/ncRNA_class="snoRNA"
/product="SNR57"
/note="C/D box small nucleolar RNA (snoRNA), guides
2'-O-methylation of small subunit (SSU) rRNA at position
G1572"
/db_xref="SGD:S000006448"
/db_xref="GeneID:9164947"
gene complement(795573..795899)
/gene="RPS25B"
/locus_tag="YLR333C"
/db_xref="GeneID:851045"
mRNA complement(795573..795899)
/gene="RPS25B"
/locus_tag="YLR333C"
/product="ribosomal 40S subunit protein S25B"
/transcript_id="NM_001182222.1"
/db_xref="GI:296146860"
/db_xref="GeneID:851045"
CDS complement(795573..795899)
/gene="RPS25B"
/locus_tag="YLR333C"
/note="Protein component of the small (40S) ribosomal
subunit; homologous to mammalian ribosomal protein S25, no
bacterial homolog; RPS25B has a paralog, RPS25A, that
arose from the whole genome duplication"
/codon_start=1
/product="ribosomal 40S subunit protein S25B"
/protein_id="NP_013437.1"
/db_xref="GI:6323365"
/db_xref="SGD:S000004325"
/db_xref="GeneID:851045"
/translation="MPPKQQLSKAAKAAAALAGGKKSKKKWSKKSMKDRAQHAVILDQ
EKYDRILKEVPTYRYVSVSVLVDRLKIGGSLARIALRHLEKEGIIKPISKHSKQAIYT
RAAASE"
LTR 796899..797088
/note="Ty1 LTR"
/db_xref="SGD:S000007092"
gene 797178..797249
/locus_tag="tE(UUC)L"
/db_xref="GeneID:851047"
tRNA 797178..797249
/locus_tag="tE(UUC)L"
/product="tRNA-Glu"
/note="Glutamate tRNA (tRNA-Glu), predicted by tRNAscan-SE
analysis; thiolation of uridine at wobble position (34)
requires Ncs6p; target of K. lactis zymocin"
/db_xref="SGD:S000006559"
/db_xref="GeneID:851047"
gene 797430..799592
/gene="NUP2"
/locus_tag="YLR335W"
/db_xref="GeneID:851048"
mRNA 797430..799592
/gene="NUP2"
/locus_tag="YLR335W"
/product="Nup2p"
/transcript_id="NM_001182224.1"
/db_xref="GI:296146861"
/db_xref="GeneID:851048"
CDS 797430..799592
/gene="NUP2"
/locus_tag="YLR335W"
/note="Nucleoporin involved in nucleocytoplasmic
transport, binds to either the nucleoplasmic or
cytoplasmic faces of the nuclear pore complex depending on
Ran-GTP levels; also has a role in chromatin organization"
/codon_start=1
/product="Nup2p"
/protein_id="NP_013439.1"
/db_xref="GI:6323367"
/db_xref="SGD:S000004327"
/db_xref="GeneID:851048"
/translation="MAKRVADAQIQRETYDSNESDDDVTPSTKVASSAVMNRRKIAMP
KRRMAFKPFGSAKSDETKQASSFSFLNRADGTGEAQVDNSPTTESNSRLKALNLQFKA
KVDDLVLGKPLADLRPLFTRYELYIKNILEAPVKSIENPTQTKGNDAKPAKVEDVQKS
SDSSSEDEVKVEGPKFTIDAKPPISDSVFSFGPKKENRKKDESDSENDIEIKGPEFKF
SGTVSSDVFKLNPSTDKNEKKTETNAKPFSFSSATSTTEQTKSKNPLSLTEATKTNVD
NNSKAEASFTFGTKHAADSQNNKPSFVFGQAAAKPSLEKSSFTFGSTTIEKKNDENST
SNSKPEKSSDSNDSNPSFSFSIPSKNTPDASKPSFSFGVPNSSKNETSKPVFSFGAAT
PSAKEASQEDDNNNVEKPSSKPAFNLISNAGTEKEKESKKDSKPAFSFGISNGSESKD
SDKPSLPSAVDGENDKKEATKPAFSFGINTNTTKTADTKAPTFTFGSSALADNKEDVK
KPFSFGTSQPNNTPSFSFGKTTANLPANSSTSPAPSIPSTGFKFSLPFEQKGSQTTTN
DSKEESTTEATGNESQDATKVDATPEESKPINLQNGEEDEVALFSQKAKLMTFNAETK
SYDSRGVGEMKLLKKKDDPSKVRLLCRSDGMGNVLLNATVVDSFKYEPLAPGNDNLIK
APTVAADGKLVTYIVKFKQKEEGRSFTKAIEDAKKEMK"
gene complement(799697..802396)
/gene="SGD1"
/locus_tag="YLR336C"
/db_xref="GeneID:851049"
mRNA complement(799697..802396)
/gene="SGD1"
/locus_tag="YLR336C"
/product="Sgd1p"
/transcript_id="NM_001182225.1"
/db_xref="GI:296146862"
/db_xref="GeneID:851049"
CDS complement(799697..802396)
/gene="SGD1"
/locus_tag="YLR336C"
/note="Essential nuclear protein, required for biogenesis
of the small ribosomal subunit; has a possible role in the
osmoregulatory glycerol response; putative homolog of
human NOM1 which is implicated in acute myeloid leukemia"
/codon_start=1
/product="Sgd1p"
/protein_id="NP_013440.1"
/db_xref="GI:6323368"
/db_xref="SGD:S000004328"
/db_xref="GeneID:851049"
/translation="MQKTDGIRIPGVILDELKTLDYSQDERFSISEGKKRRRGNGKHL
SRKEKRKMERADKKRKIISTREINSSRLKSAPTSEKRSANAGVKNVGKQANGKNPISS
DESESNENWDSDEVLTDEVAEESGEQAMSAEETMKKLESLKRKAKGIQGAENSGEIKG
NSYEKKHIRNRDTNENFVSYPLAPSDRSAFERDEMDMQYYAKKLGLKGERKAIHAKDE
FDAIGGLLEGLEYFENYGKSDEEYGDFATETNSMRKDDEASEKAFSSDDDLSASDFED
SDGLSESDNDSVADSDDNYRREKENPYVAPTQSVESYVPPSLRKKLDDSENNSTLSEI
SKKVNSSLNKLSDSNITIIITDLNRLYDSLPRQYVTESLTKGILNIISQNQKLLDGFI
MNYAALAYTLSKLRGIEVGAFFIQKTVEAFLHHYEEEMENILKDQQSKISSKICINIA
TLLSYCYNFGFVSCRLIYDIIRIFVADPNEFTTELLLRIISISGQLIRGDDPSALRDI
RSELLKNAKNLKEQSPRLRFLMDTMSDLKNNRLKPSILATDHHPLKKNLQSILNSSSS
WEPLQVSLEDIKNIDSKGKWWLVGASWRGNMENAFEVSINNENDASKSKKSKISIEDD
LLDDIPDWNIIARQQRMNTDIRRAIFISIMSAQDYLDAFSKLEKLSLKNKQVLEIPRI
VLHCLLADSGSNGYNHYYALVANKICERYSHLSKSFQFLFWDVIKKFEDKEFDSESDT
DEEDDLDDKEKLLRISNQGRFFGSLLANDILKLDVFKHVPFMGGLNTEGMLFMEILLF
QLFLTVAKKSEKKLKMDESGNKRIIYSDDYLRDVLTKNVKSENMLFILKGLKWFINKK
FRYHNFLAGKKGDKAFDRDERRLAWASKAAKSIIDKELENIDS"
gene complement(802653..805106)
/gene="VRP1"
/locus_tag="YLR337C"
/gene_synonym="END5; MDP2; YLR337W"
/db_xref="GeneID:851051"
mRNA complement(802653..805106)
/gene="VRP1"
/locus_tag="YLR337C"
/gene_synonym="END5; MDP2; YLR337W"
/product="Vrp1p"
/transcript_id="NM_001182226.1"
/db_xref="GI:296146863"
/db_xref="GeneID:851051"
CDS complement(802653..805106)
/gene="VRP1"
/locus_tag="YLR337C"
/gene_synonym="END5; MDP2; YLR337W"
/note="Proline-rich actin-associated protein involved in
cytoskeletal organization and cytokinesis; related to
mammalian Wiskott-Aldrich syndrome protein
(WASP)-interacting protein (WIP)"
/codon_start=1
/product="Vrp1p"
/protein_id="NP_013441.1"
/db_xref="GI:6323370"
/db_xref="SGD:S000004329"
/db_xref="GeneID:851051"
/translation="MAGAPAPPPPPPPPALGGSAPKPAKSVMQGRDALLGDIRKGMKL
KKAETNDRSAPIVGGGVVSSASGSSGTVSSKGPSMSAPPIPGMGAPQLGDILAGGIPK
LKHINNNASTKPSPSASAPPIPGAVPSVAAPPIPNAPLSPAPAVPSIPSSSAPPIPDI
PSSAAPPIPIVPSSPAPPLPLSGASAPKVPQNRPHMPSVRPAHRSHQRKSSNISLPSV
SAPPLPSASLPTHVSNPPQAPPPPPTPTIGLDSKNIKPTDNAVSPPSSEVPAGGLPFL
AEINARRSERGAVEGVSSTKIQTENHKSPSQPPLPSSAPPIPTSHAPPLPPTAPPPPS
LPNVTSAPKKATSAPAPPPPPLPAAMSSASTNSVKATPVPPTLAPPLPNTTSVPPNKA
SSMPAPPPPPPPPPGAFSTSSALSASSIPLAPLPPPPPPSVATSVPSAPPPPPTLTTN
KPSASSKQSKISSSSSSSAVTPGGPLPFLAEIQKKRDDRFVVGGDTGYTTQDKQEDVI
GSSKDDNVRPSPISPSINPPKQSSQNGMSFLDEIESKLHKQTSSNAFNAPPPHTDAMA
PPLPPSAPPPPITSLPTPTASGDDHTNDKSETVLGMKKAKAPALPGHVPPPPVPPVLS
DDSKNNVPAASLLHDVLPSSNLEKPPSPPVAAAPPLPTFSAPSLPQQSVSTSIPSPPP
VAPTLSVRTETESISKNPTKSPPPPPSPSTMDTGTSNSPSKNLKQRLFSTGGSTLQHK
HNTHTNQPDVDVGRYTIGGSNSIVGAKSGNERIVIDDSRFKWTNVSQMPKPRPFQNKT
KLYPSGKGSSVPLDLTLFT"
gene 805887..806825
/gene="RPP0"
/locus_tag="YLR340W"
/gene_synonym="RPL10E"
/db_xref="GeneID:851052"
mRNA 805887..806825
/gene="RPP0"
/locus_tag="YLR340W"
/gene_synonym="RPL10E"
/product="ribosomal protein P0"
/transcript_id="NM_001182229.1"
/db_xref="GI:296146864"
/db_xref="GeneID:851052"
CDS 805887..806825
/gene="RPP0"
/locus_tag="YLR340W"
/gene_synonym="RPL10E"
/note="Conserved ribosomal protein P0 of the ribosomal
stalk, which is involved in interaction between
translational elongation factors and the ribosome; similar
to rat P0, human P0, and E. coli L10e; phosphorylated on
serine 302"
/codon_start=1
/product="ribosomal protein P0"
/protein_id="NP_013444.1"
/db_xref="GI:6323371"
/db_xref="SGD:S000004332"
/db_xref="GeneID:851052"
/translation="MGGIREKKAEYFAKLREYLEEYKSLFVVGVDNVSSQQMHEVRKE
LRGRAVVLMGKNTMVRRAIRGFLSDLPDFEKLLPFVKGNVGFVFTNEPLTEIKNVIVS
NRVAAPARAGAVAPEDIWVRAVNTGMEPGKTSFFQALGVPTKIARGTIEIVSDVKVVD
AGNKVGQSEASLLNLLNISPFTFGLTVVQVYDNGQVFPSSILDITDEELVSHFVSAVS
TIASISLAIGYPTLPSVGHTLINNYKDLLAVAIAASYHYPEIEDLVDRIENPEKYAAA
APAATSAASGDAAPAEEAAAEEEEESDDDMGFGLFD"
gene 807385..808818
/gene="SPO77"
/locus_tag="YLR341W"
/db_xref="GeneID:851054"
mRNA 807385..808818
/gene="SPO77"
/locus_tag="YLR341W"
/product="Spo77p"
/transcript_id="NM_001182230.1"
/db_xref="GI:296146865"
/db_xref="GeneID:851054"
CDS 807385..808818
/gene="SPO77"
/locus_tag="YLR341W"
/note="Meiosis-specific hypothetical protein, required for
spore wall formation during sporulation; dispensable for
both nuclear divisions during meiosis"
/codon_start=1
/product="Spo77p"
/protein_id="NP_013445.1"
/db_xref="GI:6323373"
/db_xref="SGD:S000004333"
/db_xref="GeneID:851054"
/translation="MFRRGDNSNFNVQNSFFLPLEYEYTVKDNVPSKKKSSIGFFPLD
DSLFTSKNNSGHHKSEQLHRGNAETIRSQFGTDAVPIRIDEKEGKWDRIQDDNSSNLN
YQINNSNDPASSGKYTQSIDCNHIAESKFSKKNGNIDSLRSNSATFMLNTADEDVIEF
SFDDNVPYAELLSGATLEKCSLTLNEINKKLFNTLYDFRVSKDNPEENLVELILPNCV
VLLNFFEDIELLADSSDEAFEKSTFINTIEFIVHDIWVETLIKNINLLQMFDADLKCY
NDKYIICKLKGQYPSTNIVDIMCRLKHFSNSILETFKFGIELKEQDQCHNRNTIINYV
LFSRVFSTIVLEIQKCFILIVKFMYSVNFLEKFSDEVFLSFIEILIKIVFEHQIPQLF
LGIDEIIQLWLKNNEGKRQQLLSAWCNGTVQDMKQSQQRESSNAESESITSSTEEDEE
GLQFNKWDVIEPFIDNIKALNQSKSHM"
gene 809997..815627
/gene="FKS1"
/locus_tag="YLR342W"
/gene_synonym="CND1; CWH53; ETG1; GSC1; PBR1"
/db_xref="GeneID:851055"
mRNA 809997..815627
/gene="FKS1"
/locus_tag="YLR342W"
/gene_synonym="CND1; CWH53; ETG1; GSC1; PBR1"
/product="Fks1p"
/transcript_id="NM_001182231.1"
/db_xref="GI:296146866"
/db_xref="GeneID:851055"
CDS 809997..815627
/gene="FKS1"
/locus_tag="YLR342W"
/gene_synonym="CND1; CWH53; ETG1; GSC1; PBR1"
/EC_number="2.4.1.34"
/note="Catalytic subunit of 1,3-beta-D-glucan synthase,
functionally redundant with alternate catalytic subunit
Gsc2p; binds to regulatory subunit Rho1p; involved in cell
wall synthesis and maintenance; localizes to sites of cell
wall remodeling"
/codon_start=1
/product="Fks1p"
/protein_id="NP_013446.1"
/db_xref="GI:6323374"
/db_xref="SGD:S000004334"
/db_xref="GeneID:851055"
/translation="MNTDQQPYQGQTDYTQGPGNGQSQEQDYDQYGQPLYPSQADGYY
DPNVAAGTEADMYGQQPPNESYDQDYTNGEYYGQPPNMAAQDGENFSDFSSYGPPGTP
GYDSYGGQYTASQMSYGEPNSSGTSTPIYGNYDPNAIAMALPNEPYPAWTADSQSPVS
IEQIEDIFIDLTNRLGFQRDSMRNMFDHFMVLLDSRSSRMSPDQALLSLHADYIGGDT
ANYKKWYFAAQLDMDDEIGFRNMSLGKLSRKARKAKKKNKKAMEEANPEDTEETLNKI
EGDNSLEAADFRWKAKMNQLSPLERVRHIALYLLCWGEANQVRFTAECLCFIYKCALD
YLDSPLCQQRQEPMPEGDFLNRVITPIYHFIRNQVYEIVDGRFVKRERDHNKIVGYDD
LNQLFWYPEGIAKIVLEDGTKLIELPLEERYLRLGDVVWDDVFFKTYKETRTWLHLVT
NFNRIWVMHISIFWMYFAYNSPTFYTHNYQQLVDNQPLAAYKWASCALGGTVASLIQI
VATLCEWSFVPRKWAGAQHLSRRFWFLCIIFGINLGPIIFVFAYDKDTVYSTAAHVVA
AVMFFVAVATIIFFSIMPLGGLFTSYMKKSTRRYVASQTFTAAFAPLHGLDRWMSYLV
WVTVFAAKYSESYYFLVLSLRDPIRILSTTAMRCTGEYWWGAVLCKVQPKIVLGLVIA
TDFILFFLDTYLWYIIVNTIFSVGKSFYLGISILTPWRNIFTRLPKRIYSKILATTDM
EIKYKPKVLISQVWNAIIISMYREHLLAIDHVQKLLYHQVPSEIEGKRTLRAPTFFVS
QDDNNFETEFFPRDSEAERRISFFAQSLSTPIPEPLPVDNMPTFTVLTPHYAERILLS
LREIIREDDQFSRVTLLEYLKQLHPVEWECFVKDTKILAEETAAYEGNENEAEKEDAL
KSQIDDLPFYCIGFKSAAPEYTLRTRIWASLRSQTLYRTISGFMNYSRAIKLLYRVEN
PEIVQMFGGNAEGLERELEKMARRKFKFLVSMQRLAKFKPHELENAEFLLRAYPDLQI
AYLDEEPPLTEGEEPRIYSALIDGHCEILDNGRRRPKFRVQLSGNPILGDGKSDNQNH
ALIFYRGEYIQLIDANQDNYLEECLKIRSVLAEFEELNVEQVNPYAPGLRYEEQTTNH
PVAIVGAREYIFSENSGVLGDVAAGKEQTFGTLFARTLSQIGGKLHYGHPDFINATFM
TTRGGVSKAQKGLHLNEDIYAGMNAMLRGGRIKHCEYYQCGKGRDLGFGTILNFTTKI
GAGMGEQMLSREYYYLGTQLPVDRFLTFYYAHPGFHLNNLFIQLSLQMFMLTLVNLSS
LAHESIMCIYDRNKPKTDVLVPIGCYNFQPAVDWVRRYTLSIFIVFWIAFVPIVVQEL
IERGLWKATQRFFCHLLSLSPMFEVFAGQIYSSALLSDLAIGGARYISTGRGFATSRI
PFSILYSRFAGSAIYMGARSMLMLLFGTVAHWQAPLLWFWASLSSLIFAPFVFNPHQF
AWEDFFLDYRDYIRWLSRGNNQYHRNSWIGYVRMSRARITGFKRKLVGDESEKAAGDA
SRAHRTNLIMAEIIPCAIYAAGCFIAFTFINAQTGVKTTDDDRVNSVLRIIICTLAPI
AVNLGVLFFCMGMSCCSGPLFGMCCKKTGSVMAGIAHGVAVIVHIAFFIVMWVLESFN
FVRMLIGVVTCIQCQRLIFHCMTALMLTREFKNDHANTAFWTGKWYGKGMGYMAWTQP
SRELTAKVIELSEFAADFVLGHVILICQLPLIIIPKIDKFHSIMLFWLKPSRQIRPPI
YSLKQTRLRKRMVKKYCSLYFLVLAIFAGCIIGPAVASAKIHKHIGDSLDGVVHNLFQ
PINTTNNDTGSQMSTYQSHYYTHTPSLKTWSTIK"
gene 815810..815983
/locus_tag="YLR342W-A"
/db_xref="GeneID:1466421"
mRNA 815810..815983
/locus_tag="YLR342W-A"
/product="hypothetical protein"
/transcript_id="NM_001184569.1"
/db_xref="GI:296146867"
/db_xref="GeneID:1466421"
CDS 815810..815983
/locus_tag="YLR342W-A"
/codon_start=1
/product="hypothetical protein"
/protein_id="NP_878133.1"
/db_xref="GI:33438845"
/db_xref="SGD:S000028571"
/db_xref="GeneID:1466421"
/translation="MNVFMPIRVFLYSYVIINSLLSSFFHQYRPLFIKNGAAFGVSNS
EKICVTLIVNELI"
gene 816094..817761
/gene="GAS2"
/locus_tag="YLR343W"
/db_xref="GeneID:851056"
mRNA 816094..817761
/gene="GAS2"
/locus_tag="YLR343W"
/product="Gas2p"
/transcript_id="NM_001182232.1"
/db_xref="GI:296146868"
/db_xref="GeneID:851056"
CDS 816094..817761
/gene="GAS2"
/locus_tag="YLR343W"
/note="1,3-beta-glucanosyltransferase, involved with Gas4p
in spore wall assembly; has similarity to Gas1p"
/codon_start=1
/product="Gas2p"
/protein_id="NP_013447.1"
/db_xref="GI:6323375"
/db_xref="SGD:S000004335"
/db_xref="GeneID:851056"
/translation="MNKKQNFYAAIIVAIFLCLQLSHGSSGVSFEKTPAIKIVGNKFF
DSESGEQFFIKGIAYQLQRSEEELSNANGAFETSYIDALADPKICLRDIPFLKMLGVN
TLRVYAIDPTKSHDICMEALSAEGMYVLLDLSEPDISINRENPSWDVHIFERYKSVID
AMSSFPNLLGYFAGNEVTNDHTNTFASPFVKAAIRDAKEYISHSNHRKIPVGYSTNDD
AMTRDNLARYFVCGDVKADFYGINMYEWCGYSTYGTSGYRERTKEFEGYPIPVFFSEF
GCNLVRPRPFTEVSALYGNKMSSVWSGGLAYMYFEEENEYGVVKINDNDGVDILPDFK
NLKKEFAKADPKGITEEEYLTAKEPTEVESVECPHIAVGVWEANEKLPETPDRSKCAC
LDEILPCEIVPFGAESGKYEEYFSYLCSKVDCSDILANGKTGEYGEFSDCSVEQKLSL
QLSKLYCKIGANDRHCPLNDKNVYFNLESLQPLTSESICKNVFDSIRNITYNHGDYSK
SNPSRSKESLNVKYPSSEERENDGTIAFKTSGFVILLISMIAAGILL"
LTR complement(818073..818403)
/note="Ty1 LTR"
/db_xref="SGD:S000007074"
gene 818609..818680
/gene="TRR4"
/locus_tag="tR(CCG)L"
/db_xref="GeneID:851057"
tRNA 818609..818680
/gene="TRR4"
/locus_tag="tR(CCG)L"
/product="tRNA-Arg"
/note="Arginine tRNA (tRNA-Arg), predicted by tRNAscan-SE
analysis; single essential nuclear tRNA gene containing
the tDNA-anticodon CCG (presumably CCG in the mature
tRNA), decodes CGG codons into arginine, one of 19 nuclear
tRNAs for arginine; correct folding and efficient
aminoacylation require Lhp1p"
/db_xref="SGD:S000006706"
/db_xref="GeneID:851057"
gene 819312..820142
/gene="RPL26A"
/locus_tag="YLR344W"
/db_xref="GeneID:851058"
mRNA join(819312..819330,819778..820142)
/gene="RPL26A"
/locus_tag="YLR344W"
/product="ribosomal 60S subunit protein L26A"
/transcript_id="NM_001182233.1"
/db_xref="GI:296146869"
/db_xref="GeneID:851058"
CDS join(819312..819330,819778..820142)
/gene="RPL26A"
/locus_tag="YLR344W"
/note="Ribosomal 60S subunit protein L26A; binds to 5.8S
rRNA; homologous to mammalian ribosomal protein L26 and
bacterial L24; RPL26A has a paralog, RPL26B, that arose
from the whole genome duplication"
/codon_start=1
/product="ribosomal 60S subunit protein L26A"
/protein_id="NP_013448.1"
/db_xref="GI:6323376"
/db_xref="SGD:S000004336"
/db_xref="GeneID:851058"
/translation="MAKQSLDVSSDRRKARKAYFTAPSSQRRVLLSAPLSKELRAQYG
IKALPIRRDDEVLVVRGSKKGQEGKISSVYRLKFAVQVDKVTKEKVNGASVPINLHPS
KLVITKLHLDKDRKALIQRKGGKLE"
gene 820511..822040
/locus_tag="YLR345W"
/db_xref="GeneID:851059"
mRNA 820511..822040
/locus_tag="YLR345W"
/product="bifunctional fructose-2,6-bisphosphate
2-phosphatase/6-phosphofructo-2-kinase"
/transcript_id="NM_001182234.1"
/db_xref="GI:296146870"
/db_xref="GeneID:851059"
CDS 820511..822040
/locus_tag="YLR345W"
/EC_number="2.7.1.105"
/EC_number="3.1.3.46"
/note="Similar to
6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase
enzymes responsible for the metabolism of
fructoso-2,6-bisphosphate; mRNA expression is repressed by
the Rfx1p-Tup1p-Ssn6p repressor complex; YLR345W is not an
essential gene"
/codon_start=1
/product="bifunctional fructose-2,6-bisphosphate
2-phosphatase/6-phosphofructo-2-kinase"
/protein_id="NP_013449.1"
/db_xref="GI:6323377"
/db_xref="SGD:S000004337"
/db_xref="GeneID:851059"
/translation="MPNVLSDDEELLNGLGSEIMKPSRQGNHMARTVKRWVNKERATT
ADLKNVNIDGVHGPVNTESYISPGQLYSTDSGNLFHAGRILVVLVGLPATSKTLLSVA
ITRYTRWLGVRTKSFHFSEYKESAKNIPSDYFCVVPTSKEGVAFVEKLRMQMLNDILA
FFNDLSGQLAIYDALNIRKIDRKNLETTFSEIGVKVLFIESIVSDQEIMNRNIALALE
SNDYKGLSTDEAIDEYMRRLSVNEPYYEMMTHDEELSYIKYINLGKQIIVKDNIHGYL
VNKIVFFLMNLRQKKGCVYFARCGTSDKDNYIHDEELNEEGIHYSQVLKDFVLQRIKQ
KRQAKKNSDSLVEVIDGSHDEDLKTSLIVWTGPRKRTHDTALFFSKEGIKVQQRSELR
QLNPGSIADLTDQQIMDKFPSEYKESLKDPYHFRFPRAESYHDLAVRMEPLLLEMEHT
SKDILIIAHESTLRVLYGYLMACTCVELPNLNFTRDKLVEISFSPFCNTVELLNIPLT
S"
gene complement(822287..822592)
/locus_tag="YLR346C"
/db_xref="GeneID:851060"
mRNA complement(822287..822592)
/locus_tag="YLR346C"
/product="hypothetical protein"
/transcript_id="NM_001182235.1"
/db_xref="GI:296146871"
/db_xref="GeneID:851060"
CDS complement(822287..822592)
/locus_tag="YLR346C"
/note="hypothetical protein found in mitochondria;
expression is regulated by transcription factors involved
in pleiotropic drug resistance, Pdr1p and Yrr1p; YLR346C
is not an essential gene"
/codon_start=1
/product="hypothetical protein"
/protein_id="NP_013450.1"
/db_xref="GI:6323378"
/db_xref="SGD:S000004338"
/db_xref="GeneID:851060"
/translation="MQSISNCPIGLVSKNTINSASTIAEWVACPWKYINVVGSGRYVS
NKPDKITRYDLLKAAQEAEMQELLTRNDMKGRHKRNKKSKIALETIAEENSSTESLF"
gene complement(823828..826413)
/gene="KAP95"
/locus_tag="YLR347C"
/gene_synonym="RSL1"
/db_xref="GeneID:851061"
mRNA complement(823828..826413)
/gene="KAP95"
/locus_tag="YLR347C"
/gene_synonym="RSL1"
/product="Kap95p"
/transcript_id="NM_001182236.1"
/db_xref="GI:296146872"
/db_xref="GeneID:851061"
CDS complement(823828..826413)
/gene="KAP95"
/locus_tag="YLR347C"
/gene_synonym="RSL1"
/note="Karyopherin beta, forms a complex with
Srp1p/Kap60p; interacts with nucleoporins to mediate
nuclear import of NLS-containing cargo proteins via the
nuclear pore complex; regulates PC biosynthesis;
GDP-to-GTP exchange factor for Gsp1p"
/codon_start=1
/product="Kap95p"
/protein_id="NP_013451.1"
/db_xref="GI:6323379"
/db_xref="SGD:S000004339"
/db_xref="GeneID:851061"
/translation="MSTAEFAQLLENSILSPDQNIRLTSETQLKKLSNDNFLQFAGLS
SQVLIDENTKLEGRILAALTLKNELVSKDSVKTQQFAQRWITQVSPEAKNQIKTNALT
ALVSIEPRIANAAAQLIAAIADIELPHGAWPELMKIMVDNTGAEQPENVKRASLLALG
YMCESADPQSQALVSSSNNILIAIVQGAQSTETSKAVRLAALNALADSLIFIKNNMER
EGERNYLMQVVCEATQAEDIEVQAAAFGCLCKIMSLYYTFMKPYMEQALYALTIATMK
SPNDKVASMTVEFWSTICEEEIDIAYELAQFPQSPLQSYNFALSSIKDVVPNLLNLLT
RQNEDPEDDDWNVSMSAGACLQLFAQNCGNHILEPVLEFVEQNITADNWRNREAAVMA
FGSIMDGPDKVQRTYYVHQALPSILNLMNDQSLQVKETTAWCIGRIADSVAESIDPQQ
HLPGVVQACLIGLQDHPKVATNCSWTIINLVEQLAEATPSPIYNFYPALVDGLIGAAN
RIDNEFNARASAFSALTTMVEYATDTVAETSASISTFVMDKLGQTMSVDENQLTLEDA
QSLQELQSNILTVLAAVIRKSPSSVEPVADMLMGLFFRLLEKKDSAFIEDDVFYAISA
LAASLGKGFEKYLETFSPYLLKALNQVDSPVSITAVGFIADISNSLEEDFRRYSDAMM
NVLAQMISNPNARRELKPAVLSVFGDIASNIGADFIPYLNDIMALCVAAQNTKPENGT
LEALDYQIKVLEAVLDAYVGIVAGLHDKPEALFPYVGTIFQFIAQVAEDPQLYSEDAT
SRAAVGLIGDIAAMFPDGSIKQFYGQDWVIDYIKRTRSGQLFSQATKDTARWAREQQK
RQLSL"
gene complement(826977..827873)
/gene="DIC1"
/locus_tag="YLR348C"
/db_xref="GeneID:851063"
mRNA complement(826977..827873)
/gene="DIC1"
/locus_tag="YLR348C"
/product="Dic1p"
/transcript_id="NM_001182237.1"
/db_xref="GI:296146873"
/db_xref="GeneID:851063"
CDS complement(826977..827873)
/gene="DIC1"
/locus_tag="YLR348C"
/note="Mitochondrial dicarboxylate carrier, integral
membrane protein, catalyzes a dicarboxylate-phosphate
exchange across the inner mitochondrial membrane,
transports cytoplasmic dicarboxylates into the
mitochondrial matrix"
/codon_start=1
/product="Dic1p"
/protein_id="NP_013452.1"
/db_xref="GI:6323381"
/db_xref="SGD:S000004340"
/db_xref="GeneID:851063"
/translation="MSTNAKESAGKNIKYPWWYGGAAGIFATMVTHPLDLAKVRLQAA
PMPKPTLFRMLESILANEGVVGLYSGLSAAVLRQCTYTTVRFGAYDLLKENVIPREQL
TNMAYLLPCSMFSGAIGGLAGNFADVVNIRMQNDSALEAAKRRNYKNAIDGVYKIYRY
EGGLKTLFTGWKPNMVRGILMTASQVVTYDVFKNYLVTKLDFDASKNYTHLTASLLAG
LVATTVCSPADVMKTRIMNGSGDHQPALKILADAVRKEGPSFMFRGWLPSFTRLGPFT
MLIFFAIEQLKKHRVGMPKEDK"
gene 828730..829380
/gene="ORM2"
/locus_tag="YLR350W"
/db_xref="GeneID:851064"
mRNA 828730..829380
/gene="ORM2"
/locus_tag="YLR350W"
/product="Orm2p"
/transcript_id="NM_001182239.1"
/db_xref="GI:296146874"
/db_xref="GeneID:851064"
CDS 828730..829380
/gene="ORM2"
/locus_tag="YLR350W"
/note="Evolutionarily conserved protein, similar to Orm1p;
required for resistance to agents that induce unfolded
protein response; Orm1p and Orm2p together control
membrane biogenesis by coordinating lipid homeostasis with
protein quality control; protein abundance increases in
response to DNA replication stress"
/codon_start=1
/product="Orm2p"
/protein_id="NP_013454.1"
/db_xref="GI:6323382"
/db_xref="SGD:S000004342"
/db_xref="GeneID:851064"
/translation="MIDRTKNESPAFEESPLTPNVSNLKPFPSQSNKISTPVTDHRRR
RSSSVISHVEQETFEDENDQQMLPNMNATWVDQRGAWLIHIVVIVLLRLFYSLFGSTP
KWTWTLTNMTYIIGFYIMFHLVKGTPFDFNGGAYDNLTMWEQINDETLYTPTRKFLLI
VPIVLFLISNQYYRNDMTLFLSNLAVTVLIGVVPKLGITHRLRISIPGITGRAQIS"
gene complement(829489..830364)
/gene="NIT3"
/locus_tag="YLR351C"
/db_xref="GeneID:851065"
mRNA complement(829489..830364)
/gene="NIT3"
/locus_tag="YLR351C"
/product="Nit3p"
/transcript_id="NM_001182240.1"
/db_xref="GI:296146875"
/db_xref="GeneID:851065"
CDS complement(829489..830364)
/gene="NIT3"
/locus_tag="YLR351C"
/EC_number="3.5.-.-"
/note="Nit protein, one of two proteins in S. cerevisiae
with similarity to the Nit domain of NitFhit from fly and
worm and to the mouse and human Nit protein which
interacts with the Fhit tumor suppressor; nitrilase
superfamily member"
/codon_start=1
/product="Nit3p"
/protein_id="NP_013455.1"
/db_xref="GI:6323383"
/db_xref="SGD:S000004343"
/db_xref="GeneID:851065"
/translation="MSASKILSQKIKVALVQLSGSSPDKMANLQRAATFIERAMKEQP
DTKLVVLPECFNSPYSTDQFRKYSEVINPKEPSTSVQFLSNLANKFKIILVGGTIPEL
DPKTDKIYNTSIIFNEDGKLIDKHRKVHLFDVDIPNGISFHESETLSPGEKSTTIDTK
YGKFGVGICYDMRFPELAMLSARKGAFAMIYPSAFNTVTGPLHWHLLARSRAVDNQVY
VMLCSPARNLQSSYHAYGHSIVVDPRGKIVAEAGEGEEIIYAELDPEVIESFRQAVPL
TKQRRFDVYSDVNAH"
gene 831116..833539
/locus_tag="YLR352W"
/db_xref="GeneID:851066"
mRNA 831116..833539
/locus_tag="YLR352W"
/product="hypothetical protein"
/transcript_id="NM_001182241.1"
/db_xref="GI:296146876"
/db_xref="GeneID:851066"
CDS 831116..833539
/locus_tag="YLR352W"
/note="hypothetical protein with similarity to F-box
proteins; interacts with Skp1p and Cdc53p; YLR352W is not
an essential gene"
/codon_start=1
/product="hypothetical protein"
/protein_id="NP_013456.1"
/db_xref="GI:6323384"
/db_xref="SGD:S000004344"
/db_xref="GeneID:851066"
/translation="MPDLKSKTLSSQSLGAAIPPEIVYQILTYQFRDLLRNDHPGTAE
KFNENLTTFVKSNLTVNKTFSHICQVLIYRYCNLTTAKRFHGLLQTLKGNRCLCNKIE
VADFQELTSIGLGRSSEMNKMIKNLTNETLLEFLMLTKANLREFLACENIQDDLDDNI
IKYILSPGKVLSVVDFCGCSGTTFTESFIKALDKYYPNKSIDQYRLEPIQQNYQITCL
GLNDCIDLPSHVLWKILKMLPELQKLDLSHTSIDDSTLYHGIPHWKNLTHLSLATCLQ
VTPRAVLEFFSHHPTITDPDNTSTLEWLNVSVIAHSSSWNEVHTMFLLKKLCQHGHNK
TLQYLNIGGLPLHVAPSFGEDPISESTYYYQCRDSLQFIKWNFPKLKSLSIKGNSIPI
STLVEFLTPIDQDHPNCAQKLKFLNISGNSYVNKWTIQDSLLYTCSPSLVALEVSFDS
WQQIEKLNDRHEIIAYRYKNPNSVIKDISTAEQVKWKCYIDSSYGRRYWLYKTDPFLN
RDDLDSKSNLTRYDFEGHKIIEIINQPDFLKFAQSKIMLGCGLVPQSGIRRKLCYRDL
KPPVSQFLNRKGAISLGDTPLPIITPTLPRGGWRIIHNEDDNNSHVEDSQNHVNAIPR
RNSLLSRPTLRSNNGSSSANPFAINVSPASQIRDGLYWDRSVHDLRELSLQEQRIQEL
ADEQQELRTIANFEETDDEYLHDPDLQRRRSQLHLFESSRSRSGNKTRPSLTGEHSSS
ASFLSFSHFNHLHKRKNYYFTHPDEFVYDPKDPLTTQRYRLHFEIVNEYQVFGCIERG
MYRYYSLKA"
gene 834352..836163
/gene="BUD8"
/locus_tag="YLR353W"
/db_xref="GeneID:851067"
mRNA 834352..836163
/gene="BUD8"
/locus_tag="YLR353W"
/product="Bud8p"
/transcript_id="NM_001182242.1"
/db_xref="GI:296146877"
/db_xref="GeneID:851067"
CDS 834352..836163
/gene="BUD8"
/locus_tag="YLR353W"
/note="Protein involved in bud-site selection; diploid
mutants display a unipolar budding pattern instead of the
wild-type bipolar pattern, and bud at the proximal pole"
/codon_start=1
/product="Bud8p"
/protein_id="NP_013457.1"
/db_xref="GI:6323385"
/db_xref="SGD:S000004345"
/db_xref="GeneID:851067"
/translation="MIQSDEDNLDSSETTASTSYSGTSSVSSRLQLRTSLFFENLNGA
HGNPDAETEMATVAYETTSRGQGFAVYINNERFSQIMGASTSSSSSSNSSSITQFHDT
QDNNIPSNTTVRPTSLRRDNEDTVPLRNVTPSQNAAVRPERAVNSPSSQRLSCALTIS
TSVLMGEDVEGSPIEQEHSRVVSSLYSSLANRGNDESKNGTPPRPTSIEPNETTEHSF
FSYHYDDTLEPDVEEAVRLTKNKTSNVNFISSTGSKGEGETEDEVIDQYEPVNESKFI
PHKLKIPEKAGSIKSSTSDDSHSPGAPGTSARKIKIPQSPSLIGNILIPSHNSDSSNE
SSPKDHIGHNNEEKFSSKSTRKPSTSLEEEGPPIGLPSIPVLRSVSGPSKWTKTPLRL
ESGNSTKSDPFSRYEGHKTPSPLTKMNKKKNKTLPEHGQPLVLAPIKSQSSESDTGQN
SIIEKPARSIRRKQQEKTDNRKEDRHDAENIDLEARMPIQHIDTASIHSFDSGQNGFR
DVYSIENIIVILLCCSIVPPLFFIIGCSSRRKLVSDYRLMRLLMNKEHRAALLQGFIW
DVDLRWFRMFCLILGAAETVIVMAGIAIGFGVGITRE"
gene complement(836350..837357)
/gene="TAL1"
/locus_tag="YLR354C"
/db_xref="GeneID:851068"
mRNA complement(836350..837357)
/gene="TAL1"
/locus_tag="YLR354C"
/product="sedoheptulose-7-phosphate:D-glyceraldehyde-3-
phosphate transaldolase TAL1"
/transcript_id="NM_001182243.1"
/db_xref="GI:296146878"
/db_xref="GeneID:851068"
CDS complement(836350..837357)
/gene="TAL1"
/locus_tag="YLR354C"
/EC_number="2.2.1.2"
/note="Transaldolase, enzyme in the non-oxidative pentose
phosphate pathway; converts sedoheptulose 7-phosphate and
glyceraldehyde 3-phosphate to erythrose 4-phosphate and
fructose 6-phosphate"
/codon_start=1
/product="sedoheptulose-7-phosphate:D-glyceraldehyde-3-
phosphate transaldolase TAL1"
/protein_id="NP_013458.1"
/db_xref="GI:6323386"
/db_xref="SGD:S000004346"
/db_xref="GeneID:851068"
/translation="MSEPAQKKQKVANNSLEQLKASGTVVVADTGDFGSIAKFQPQDS
TTNPSLILAAAKQPTYAKLIDVAVEYGKKHGKTTEEQVENAVDRLLVEFGKEILKIVP
GRVSTEVDARLSFDTQATIEKARHIIKLFEQEGVSKERVLIKIASTWEGIQAAKELEE
KDGIHCNLTLLFSFVQAVACAEAQVTLISPFVGRILDWYKSSTGKDYKGEADPGVISV
KKIYNYYKKYGYKTIVMGASFRSTDEIKNLAGVDYLTISPALLDKLMNSTEPFPRVLD
PVSAKKEAGDKISYISDESKFRFDLNEDAMATEKLSEGIRKFSADIVTLFDLIEKKVT
A"
gene complement(838066..839253)
/gene="ILV5"
/locus_tag="YLR355C"
/db_xref="GeneID:851069"
mRNA complement(838066..839253)
/gene="ILV5"
/locus_tag="YLR355C"
/product="ketol-acid reductoisomerase"
/transcript_id="NM_001182244.1"
/db_xref="GI:296146879"
/db_xref="GeneID:851069"
CDS complement(838066..839253)
/gene="ILV5"
/locus_tag="YLR355C"
/EC_number="1.1.1.86"
/note="Bifunctional acetohydroxyacid reductoisomerase and
mtDNA binding protein; involved in branched-chain amino
acid biosynthesis and maintenance of wild-type
mitochondrial DNA; found in mitochondrial nucleoids"
/codon_start=1
/product="ketol-acid reductoisomerase"
/protein_id="NP_013459.1"
/db_xref="GI:6323387"
/db_xref="SGD:S000004347"
/db_xref="GeneID:851069"
/translation="MLRTQAARLICNSRVITAKRTFALATRAAAYSRPAARFVKPMIT
TRGLKQINFGGTVETVYERADWPREKLLDYFKNDTFALIGYGSQGYGQGLNLRDNGLN
VIIGVRKDGASWKAAIEDGWVPGKNLFTVEDAIKRGSYVMNLLSDAAQSETWPAIKPL
LTKGKTLYFSHGFSPVFKDLTHVEPPKDLDVILVAPKGSGRTVRSLFKEGRGINSSYA
VWNDVTGKAHEKAQALAVAIGSGYVYQTTFEREVNSDLYGERGCLMGGIHGMFLAQYD
VLRENGHSPSEAFNETVEEATQSLYPLIGKYGMDYMYDACSTTARRGALDWYPIFKNA
LKPVFQDLYESTKNGTETKRSLEFNSQPDYREKLEKELDTIRNMEIWKVGKEVRKLRP
ENQ"
gene 840321..840914
/gene="ATG33"
/locus_tag="YLR356W"
/db_xref="GeneID:851070"
mRNA 840321..840914
/gene="ATG33"
/locus_tag="YLR356W"
/product="Atg33p"
/transcript_id="NM_001182245.1"
/db_xref="GI:296146880"
/db_xref="GeneID:851070"
CDS 840321..840914
/gene="ATG33"
/locus_tag="YLR356W"
/note="Mitochondrial mitophagy-specific protein; required
primarily for mitophagy induced at the post-log phase; not
required for other types of selective autophagy or
macroautophagy; conserved within fungi, but not in higher
eukaryotes"
/codon_start=1
/product="Atg33p"
/protein_id="NP_013460.1"
/db_xref="GI:6323388"
/db_xref="SGD:S000004348"
/db_xref="GeneID:851070"
/translation="MSVCLAITKGIAVSSIGLYSGLLASASLITSTTPLEVLTGSLTP
TLTTLKNAATALGAFASTFFCVSFFGAPPSLRHPYLLYGMLVAPLSSFVLGCASNYQS
RKYSKVSKESSLFPEDSKLAASELSDSIIDLGEDNHASENTPRDGKPAATTVSKPAEA
LHTGPPIHTKNLIAATAIAIVGFVQAVIGVYGEGQFI"
gene 841331..844000
/gene="RSC2"
/locus_tag="YLR357W"
/db_xref="GeneID:851071"
mRNA 841331..844000
/gene="RSC2"
/locus_tag="YLR357W"
/product="Rsc2p"
/transcript_id="NM_001182246.1"
/db_xref="GI:296146881"
/db_xref="GeneID:851071"
CDS 841331..844000
/gene="RSC2"
/locus_tag="YLR357W"
/note="Component of the RSC chromatin remodeling complex;
required for expression of mid-late sporulation-specific
genes; involved in telomere maintenance"
/codon_start=1
/product="Rsc2p"
/protein_id="NP_013461.1"
/db_xref="GI:6323389"
/db_xref="SGD:S000004349"
/db_xref="GeneID:851071"
/translation="MMPDDNSNSSTQNSSALYKDLRKEYESLFTLKEDSGLEISPIFN
VLPPKKDYPDYYAVIKNPVSFNTLKKRIPHYTDAQQFMNDVVQIPWNAKTYNTRDSGI
YKYALVLEKYLKDTIYPNLKEKYPQLVYPDLGPLPDEPGYEEFQQKLREKAEEVARAN
AARAESSSSMNSTEAARRLRKTRTSVKRESEPGTDTNNDEDYEATDMDIDNPKDADFP
DLIRKPLININPYTRKPLRDNRSTTPSHSGTPQPLGPRHRQVSRTQVKRGRPPIIDLP
YIQRMKNVMKVLKKEVLDSGIGLTDLFERLPDRHRDANYYIMIANPISLQDINKKVKT
RRYKTFQEFQNDFNLMLTNFRISHRGDPESIKISNILEKTFTSLARFELSKPDRSFIP
EGELRYPLDEVIVNNISYHVGDWALLRNQNDPQKPIVGQIFRLWKTPDGKQWLNACWY
YRPEQTVHRVDRLFYKNEVMKTGQYRDHLVSNLVGKCYVIHFTRYQRGNPDMKLEGPL
FVCEFRYNESDKIFNKIRTWKACLPEEIRDLDEATIPVNGRKFFKYPSPIRHLLPANA
TPHDRVPEPTMGSPDAPPLVGAVYMRPKMQRDDLGEYATSDDCPRYIIRPNDSPEEGQ
VDIETGTITTNTPTANALPKTGYSSSKLSSLRYNRSSMSLENQNAIGQQQIPLSRVGS
PGAGGPLTVQGLKQHQLQRLQQQQHQYQQQKRSQASRYNIPTIIDDLTSQASRGNLGN
IMIDAASSFVLPISITKNVDVLQRTDLHSQTKRSGREEMFPWKKTKGEILWFRGPSVI
VNERIINSGDPHLSLPLNRWFTTNKKRKLEYEEVEETMEDVTGKDKDDDGLEPDVENE
KESLPGPFVLGLRPSAKFTAHRLSMLRPPSSSS"
gene complement(843487..844050)
/locus_tag="YLR358C"
/db_xref="GeneID:851072"
mRNA complement(843487..844050)
/locus_tag="YLR358C"
/product="hypothetical protein"
/transcript_id="NM_001270756.1"
/db_xref="GI:398365974"
/db_xref="GeneID:851072"
CDS complement(843487..844050)
/locus_tag="YLR358C"
/note="hypothetical protein; expressed at both mRNA and
protein levels; partially overlaps ORF RSC2/YLR357W"
/codon_start=1
/product="hypothetical protein"
/protein_id="NP_001257685.1"
/db_xref="GI:398365975"
/db_xref="SGD:S000004350"
/db_xref="GeneID:851072"
/translation="MRNGKILCCHCFYNKGDHEDDEGGRSIESLCAVNLAEGLNPRTN
GPGKDSFSFSTSGSKPSSSLSFPVTSSMVSSTSSYSSFLFLLVVNHLFSGRLRCGSPE
FIIRSFTITLGPLNHNISPFVFFHGNISSLPDLLVWLCRSVRCKTSTFLVIEIGKTNE
EAASIIILPKLPLDACDVKSSIIVGIL"
gene 844282..845730
/gene="ADE13"
/locus_tag="YLR359W"
/gene_synonym="BRA1; BRA8"
/db_xref="GeneID:851073"
mRNA 844282..845730
/gene="ADE13"
/locus_tag="YLR359W"
/gene_synonym="BRA1; BRA8"
/product="adenylosuccinase ADE13"
/transcript_id="NM_001182248.1"
/db_xref="GI:296146882"
/db_xref="GeneID:851073"
CDS 844282..845730
/gene="ADE13"
/locus_tag="YLR359W"
/gene_synonym="BRA1; BRA8"
/EC_number="4.3.2.2"
/note="Adenylosuccinate lyase, catalyzes two steps in the
'de novo' purine nucleotide biosynthetic pathway;
expression is repressed by adenine and activated by Bas1p
and Pho2p; mutations in human ortholog ADSL cause
adenylosuccinase deficiency"
/codon_start=1
/product="adenylosuccinase ADE13"
/protein_id="NP_013463.1"
/db_xref="GI:6323391"
/db_xref="SGD:S000004351"
/db_xref="GeneID:851073"
/translation="MPDYDNYTTPLSSRYASKEMSATFSLRNRFSTWRKLWLNLAIAE
KELGLTVVTDEAIEQMRKHVEITDDEIAKASAQEAIVRHDVMAHVHTFGETCPAAAGI
IHLGATSCFVTDNADLIFIRDAYDIIIPKLVNVINRLAKFAMEYKDLPVLGWTHFQPA
QLTTLGKRATLWIQELLWDLRNFERARNDIGLRGVKGTTGTQASFLALFHGNHDKVEA
LDERVTELLGFDKVYPVTGQTYSRKIDIDVLAPLSSFAATAHKMATDIRLLANLKEVE
EPFEKSQIGSSAMAYKRNPMRCERVCSLARHLGSLFSDAVQTASVQWFERTLDDSAIR
RISLPSAFLTADILLSTLLNISSGLVVYPKVIERRIKGELPFMATENIIMAMVEKNAS
RQEVHERIRVLSHQAAAVVKEEGGENDLIERVKRDEFFKPIWEELDSLLEPSTFVGRA
PQQVEKFVQKDVNNALQPFQKYLNDEQVKLNV"
gene 846103..847422
/gene="VPS38"
/locus_tag="YLR360W"
/gene_synonym="VPL17"
/db_xref="GeneID:851074"
mRNA 846103..847422
/gene="VPS38"
/locus_tag="YLR360W"
/gene_synonym="VPL17"
/product="Vps38p"
/transcript_id="NM_001182249.3"
/db_xref="GI:398365982"
/db_xref="GeneID:851074"
CDS 846103..847422
/gene="VPS38"
/locus_tag="YLR360W"
/gene_synonym="VPL17"
/note="Part of a Vps34p phosphatidylinositol 3-kinase
complex that functions in carboxypeptidase Y (CPY)
sorting; binds Vps30p and Vps34p to promote production of
phosphatidylinositol 3-phosphate (PtdIns3P) which
stimulates kinase activity"
/codon_start=1
/product="Vps38p"
/protein_id="NP_013464.3"
/db_xref="GI:398365983"
/db_xref="SGD:S000004352"
/db_xref="GeneID:851074"
/translation="MKRFLLSRRQRHLRMICFHNISLFRANGDSKLIKEYGDGFIPCF
FILESIRGELLYVSEVQSGSLRKLSFQELPKLTGASTMIVLKLVGLVPSDILCTISSD
KNGIIDDKWCVLCTYTIDLNKLQPINEDTVLITGTNAPVLDLIDGSYTLAAEKIKPLK
GLVSSHKRNISQVKIKFSLAYSSLLKLNKLLEYSSQVHEEINEISSKIEDDFLSLKNQ
NHWYMRTVQKSIETLEKEVLQRKKSKKNIEMAQLESNDTINHSKTELSLMSQDESIND
DYGSIYSRFVQIKDRLDQLRFKKLYQLIGIFHSTDLFNSDRGYIYFEKPSSVNDVINR
LKLKPLNIEILLRQAGESTKHREYVNSQLGYYLLFLHLTAIQIFKAPLPYRLMYYGST
SVIDSQYPLYFTDQMISKHQAKLIKAIHYFNADILQFKQILENYRPT"
gene complement(847388..849124)
/gene="DCR2"
/locus_tag="YLR361C"
/db_xref="GeneID:851075"
mRNA complement(847388..849124)
/gene="DCR2"
/locus_tag="YLR361C"
/product="Dcr2p"
/transcript_id="NM_001182250.1"
/db_xref="GI:296146884"
/db_xref="GeneID:851075"
CDS complement(847388..849124)
/gene="DCR2"
/locus_tag="YLR361C"
/EC_number="3.1.-.-"
/note="Phosphoesterase involved in downregulation of the
unfolded protein response, at least in part via
dephosphorylation of Ire1p; dosage-dependent positive
regulator of the G1/S phase transition through control of
the timing of START"
/codon_start=1
/product="Dcr2p"
/protein_id="NP_013465.1"
/db_xref="GI:6323393"
/db_xref="SGD:S000004353"
/db_xref="GeneID:851075"
/translation="MIRLPRLYQRYLLYLVVFVVIALFYFLQAPRVEEHIGFDLALPI
SHVDNLWFQNKGLEGFSNDDKLVVNIGYDECFHIGRFYEGCFNRHELKSTLTDGHQYL
QRKRIHKDLRGSFGRRWFGKSEYLYYDVLYPALVDYFGSNLEKLNVEAVTGISKYPKD
KSLPFMDVSITFEPISIELLQKRSYISDINILFGVDCIQPIANWTLQKEFPLVKYRYS
EPAYLTYKFVGTRPVDTGAQRLQETDEGKFKIVQLADLHLGVGESECIDEYPKHEACK
ADPKTETFVQQVLDIEKPQLVVFTGDQIMGDRSIQDSETVLLKAVAPVIARKIPWAMV
WGNHDDEGSLTRWQLSEIASVLPYSLFKFSPHDTHDNTFGVGNYIYQIFSNNDTEVPV
GTLYFLDSHKYSTVGKIYPGYDWIKESQWKYIEDYHDVNLKFKTGLSMAFFHIPLPEY
LNIESKTHPGEKNPLIGMYKEGVTAPKYNSEGITTLDRLSVDVVSCGHDHCNDYCLRD
DSTPNKIWLCYGGGGGEGGYAGYGGTERRIRIYEINVNENNIHTWKRLNGSPKEIFDF
QSMLDGNSPESV"
gene complement(849383..849679)
/locus_tag="YLR361C-A"
/db_xref="GeneID:1466422"
mRNA complement(849383..849679)
/locus_tag="YLR361C-A"
/product="hypothetical protein"
/transcript_id="NM_001184659.3"
/db_xref="GI:398365988"
/db_xref="GeneID:1466422"
CDS complement(849383..849679)
/locus_tag="YLR361C-A"
/codon_start=1
/product="hypothetical protein"
/protein_id="NP_878134.3"
/db_xref="GI:398365989"
/db_xref="SGD:S000028845"
/db_xref="GeneID:1466422"
/translation="MAVSNNNNNNNSKERTQNIKEVEEKLGENPKITLKGGGKTKIMD
FEQLRKPHCVRPSARFPVEDTAGGLLRTGGHRPQISDEEVSKRHHEQSHGQEDH"
gene 849866..852019
/gene="STE11"
/locus_tag="YLR362W"
/db_xref="GeneID:851076"
mRNA 849866..852019
/gene="STE11"
/locus_tag="YLR362W"
/product="Ste11p"
/transcript_id="NM_001182251.1"
/db_xref="GI:296146886"
/db_xref="GeneID:851076"
CDS 849866..852019
/gene="STE11"
/locus_tag="YLR362W"
/EC_number="2.7.11.25"
/note="Signal transducing MEK kinase; involved in
pheromone response and pseudohyphal/invasive growth
pathways where it phosphorylates Ste7p, and the high
osmolarity response pathway, via phosphorylation of Pbs2p;
regulated by Ste20p and Ste50p; protein abundance
increases in response to DNA replication stress"
/codon_start=1
/product="Ste11p"
/protein_id="NP_013466.1"
/db_xref="GI:6323394"
/db_xref="SGD:S000004354"
/db_xref="GeneID:851076"
/translation="MEQTQTAEGTDLLIGDEKTNDLPFVQLFLEEIGCTQYLDSFIQC
NLVTEEEIKYLDKDILIALGVNKIGDRLKILRKSKSFQRDKRIEQVNRLKNLMEKVSS
LSTATLSMNSELIPEKHCVIFILNDGSAKKVNVNGCFNADSIKKRLIRRLPHELLATN
SNGEVTKMVQDYDVFVLDYTKNVLHLLYDVELVTICHANDRVEKNRLIFVSKDQTPSD
KAISTSKKLYLRTLSALSQVGPSSSNLLAQNKGISHNNAEGKLRIDNTEKDRIRQIFN
QRPPSEFISTNLAGYFPHTDMKRLQKTMRESFRHSARLSIAQRRPLSAESNNIGDILL
KHSNAVDMALLQGLDQTRLSSKLDTTKIPKLAHKRPEDNDAISNQLELLSVESGEEED
HDFFGEDSDIVSLPTKIATPKNWLKGACIGSGSFGSVYLGMNAHTGELMAVKQVEIKN
NNIGVPTDNNKQANSDENNEQEEQQEKIEDVGAVSHPKTNQNIHRKMVDALQHEMNLL
KELHHENIVTYYGASQEGGNLNIFLEYVPGGSVSSMLNNYGPFEESLITNFTRQILIG
VAYLHKKNIIHRDIKGANILIDIKGCVKITDFGISKKLSPLNKKQNKRASLQGSVFWM
SPEVVKQTATTAKADIWSTGCVVIEMFTGKHPFPDFSQMQAIFKIGTNTTPEIPSWAT
SEGKNFLRKAFELDYQYRPSALELLQHPWLDAHII"
gene complement(852495..853151)
/gene="NMD4"
/locus_tag="YLR363C"
/db_xref="GeneID:851077"
mRNA complement(852495..853151)
/gene="NMD4"
/locus_tag="YLR363C"
/product="Nmd4p"
/transcript_id="NM_001182252.3"
/db_xref="GI:398365996"
/db_xref="GeneID:851077"
CDS complement(852495..853151)
/gene="NMD4"
/locus_tag="YLR363C"
/note="Protein that may be involved in nonsense-mediated
mRNA decay; interacts with Nam7p, relocalizes from nucleus
to cytoplasmic foci upon DNA replication stress"
/codon_start=1
/product="Nmd4p"
/protein_id="NP_013467.3"
/db_xref="GI:398365997"
/db_xref="SGD:S000004355"
/db_xref="GeneID:851077"
/translation="MTQYNFIIDASAFEKGLGNIKRWCSDCTEAVTLNFYIPTFTLNE
LDFLQQRRKSFAARESLKFIDRLDDSKFANLKVFIEFPEVLDIILWSDVMEHNDSSGK
INIAKLPKRLKNLLKSCIYKCYLEGNEGLHWFLISEDPQIREMAMQCNIPSCSIVDVD
SILSKDMNDKSFRESEKFNNMMLKNGTKEESENGREIIRTNFNKTVYASRGTGELWSP
"
gene 853461..853718
/locus_tag="YLR363W-A"
/db_xref="GeneID:851078"
mRNA 853461..853718
/locus_tag="YLR363W-A"
/product="hypothetical protein"
/transcript_id="NM_001184486.1"
/db_xref="GI:296146888"
/db_xref="GeneID:851078"
CDS 853461..853718
/locus_tag="YLR363W-A"
/note="hypothetical protein; green fluorescent protein
(GFP)-fusion protein localizes to the nucleus; relocalizes
from nucleus to nucleolus upon DNA replication stress"
/codon_start=1
/product="hypothetical protein"
/protein_id="NP_076903.1"
/db_xref="GI:13129181"
/db_xref="SGD:S000007620"
/db_xref="GeneID:851078"
/translation="MPQKPLKVTKKAKDPRRVTKKQKNLRKAAPLQLKSKKKSLQHLK
KLKKSSSLTETTERLVASKVGHLELLRGTRKELEKGKKNSK"
gene 854062..854391
/gene="GRX8"
/locus_tag="YLR364W"
/db_xref="GeneID:851079"
mRNA 854062..854391
/gene="GRX8"
/locus_tag="YLR364W"
/product="glutathione-disulfide reductase GRX8"
/transcript_id="NM_001182253.3"
/db_xref="GI:398365998"
/db_xref="GeneID:851079"
CDS 854062..854391
/gene="GRX8"
/locus_tag="YLR364W"
/note="Glutaredoxin that employs a dithiol mechanism of
catalysis; monomeric; activity is low and null mutation
does not affect sensitivity to oxidative stress;
GFP-fusion protein localizes to the cytoplasm; expression
strongly induced by arsenic"
/codon_start=1
/product="glutathione-disulfide reductase GRX8"
/protein_id="NP_013468.3"
/db_xref="GI:398365999"
/db_xref="SGD:S000004356"
/db_xref="GeneID:851079"
/translation="MSAFVTKAEEMIKSHPYFQLSASWCPDCVYANSIWNKLNVQDKV
FVFDIGSLPRNEQEKWRIAFQKVVGSRNLPTIVVNGKFWGTESQLHRFEAKGTLEEEL
TKIGLLP"
gene 856442..857317
/gene="RPS22B"
/locus_tag="YLR367W"
/db_xref="GeneID:851082"
mRNA join(856442..856574,857058..857317)
/gene="RPS22B"
/locus_tag="YLR367W"
/product="ribosomal 40S subunit protein S22B"
/transcript_id="NM_001182256.1"
/db_xref="GI:296146890"
/db_xref="GeneID:851082"
CDS join(856442..856574,857058..857317)
/gene="RPS22B"
/locus_tag="YLR367W"
/note="Protein component of the small (40S) ribosomal
subunit; homologous to mammalian ribosomal protein S15A
and bacterial S8; RPS22B has a paralog, RPS22A, that arose
from the whole genome duplication"
/codon_start=1
/product="ribosomal 40S subunit protein S22B"
/protein_id="NP_013471.1"
/db_xref="GI:6323399"
/db_xref="SGD:S000004359"
/db_xref="GeneID:851082"
/translation="MTRSSVLADALNAINNAEKTGKRQVLLRPSSKVIIKFLQVMQKH
GYIGEFEYIDDHRSGKIVVQLNGRLNKCGVISPRFNVKIGDIEKWTANLLPARQFGYV
ILTTSAGIMDHEEARRKHVSGKILGFVY"
gene 856710..856920
/locus_tag="snR44"
/db_xref="GeneID:9164950"
ncRNA 856710..856920
/locus_tag="snR44"
/ncRNA_class="snoRNA"
/product="SNR44"
/note="H/ACA box small nucleolar RNA (snoRNA); guides
pseudouridylation of large subunit (LSU) rRNA at position
U1056 and small subunit (SSU) rRNA at position U106"
/db_xref="SGD:S000006504"
/db_xref="GeneID:9164950"
gene 857540..859336
/gene="MDM30"
/locus_tag="YLR368W"
/gene_synonym="DSG1"
/db_xref="GeneID:851083"
mRNA 857540..859336
/gene="MDM30"
/locus_tag="YLR368W"
/gene_synonym="DSG1"
/product="SCF ubiquitin ligase complex subunit MDM30"
/transcript_id="NM_001182257.3"
/db_xref="GI:398366010"
/db_xref="GeneID:851083"
CDS 857540..859336
/gene="MDM30"
/locus_tag="YLR368W"
/gene_synonym="DSG1"
/note="F-box component of an SCF ubiquitin protein ligase
complex; associates with and is required for Fzo1p
ubiquitination and for mitochondria fusion; stimulates
nuclear export of specific mRNAs; promotes
ubiquitin-mediated degradation of Gal4p in some strains"
/codon_start=1
/product="SCF ubiquitin ligase complex subunit MDM30"
/protein_id="NP_013472.3"
/db_xref="GI:398366011"
/db_xref="SGD:S000004360"
/db_xref="GeneID:851083"
/translation="MTKRRNLFMVGSSFTIDHLPPEIWLCISKLVGTSDLHNLCLINR
RLYLTITSDEIWKRRCYDRWINRESLDILTGNDYDSIPVSQWYSYYLRRAKWENKIFC
LLWGLTEETNPQHFREKYLHILQFRHYKLATFLHRIIKQGYIPDKRPLDLITYANYLL
KNVRHKYVFPLFYPTNAAELKNLNNMASRDAEMIYLRLSAIDTSFDDLLDAREFILNG
ICSDLLQKYKKIEEFLKLRPVTRVSKLISISTDYLDCFTQPHDSVGQTNDRATGRELH
REDFMLLRVYSREGRGYKTIILAIIQAITKRYNVDSYLARDHLVVSEPDFPDGRAFVT
VNEDFQPYIFDKEDLLSVWSNNFHNAENFESTVLPALLEPISIQHLLTEFFRELLRCK
PRPFEGYPNRAHGLRDMFPYGKVEVPRDVTMYFAFIYDLFDGMFESGMTSLRGQMLRD
LLNYVNANNFGDLNIIIGQNALKEPNDCWSNKRDYVLLDDNNKIGYFYTDIETEDTLC
ALNQYEVDGKVFITTIDILGDIRVRLAEGLTPFQGDNDKLWESFSSVVPRTDWGLFFK
GYDKERRRMQLNPYIEEKLSNLANDEQPLHNL"
gene 859552..861525
/gene="SSQ1"
/locus_tag="YLR369W"
/gene_synonym="SSC2; SSH1"
/db_xref="GeneID:851084"
mRNA 859552..861525
/gene="SSQ1"
/locus_tag="YLR369W"
/gene_synonym="SSC2; SSH1"
/product="Ssq1p"
/transcript_id="NM_001182258.1"
/db_xref="GI:296146892"
/db_xref="GeneID:851084"
CDS 859552..861525
/gene="SSQ1"
/locus_tag="YLR369W"
/gene_synonym="SSC2; SSH1"
/note="Mitochondrial hsp70-type molecular chaperone,
required for assembly of iron/sulfur clusters into
proteins at a step after cluster synthesis, and for
maturation of Yfh1p, which is a homolog of human frataxin
implicated in Friedreich's ataxia"
/codon_start=1
/product="Hsp70 family ATPase SSQ1"
/protein_id="NP_013473.1"
/db_xref="GI:6323401"
/db_xref="SGD:S000004361"
/db_xref="GeneID:851084"
/translation="MLKSGRLNFLKLNINSRLLYSTNPQLTKKVIGIDLGTTNSAVAY
IRDSNDKKSATIIENDEGQRTTPSIVAFDVKSSPQNKDQMKTLVGMAAKRQNAINSEN
TFFATKRLIGRAFNDKEVQRDMAVMPYKIVKCESNGQAYLSTSNGLIQSPSQIASILL
KYLKQTSEEYLGEKVNLAVITVPAYFNDSQRQATKDAGKLAGLNVLRVINEPTAAALS
FGIDDKRNNGLIAVYDLGGGTFDISILDIEDGVFEVRATNGDTHLGGEDFDNVIVNYI
IDTFIHENPEITREEITKNRETMQRLKDVSERAKIDLSHVKKTFIELPFVYKSKHLRV
PMTEEELDNMTLSLINRTIPPVKQALKDADIEPEDIDEVILVGGMTRMPKIRSVVKDL
FGKSPNSSVNPDETVALGAAIQGGILSGEIKNVLLLDVTPLTLGIETFGGAFSPLIPR
NTTVPVKKTEIFSTGVDGQAGVDIKVFQGERGLVRNNKLIGDLKLTGITPLPKGIPQI
YVTFDIDADGIINVSAAEKSSGKQQSITVIPNSGLSEEEIAKLIEEANANRAQDNLIR
QRLELISKADIMISDTENLFKRYEKLISSEKEYSNIVEDIKALRQAIKNFKANENDMS
IDVNGIKKATDALQGRALKLFQSATKNQQNQGK"
gene complement(861718..862254)
/gene="ARC18"
/locus_tag="YLR370C"
/db_xref="GeneID:851085"
mRNA complement(861718..862254)
/gene="ARC18"
/locus_tag="YLR370C"
/product="Arc18p"
/transcript_id="NM_001182259.3"
/db_xref="GI:398366016"
/db_xref="GeneID:851085"
CDS complement(861718..862254)
/gene="ARC18"
/locus_tag="YLR370C"
/note="Subunit of the ARP2/3 complex, which is required
for the motility and integrity of cortical actin patches"
/codon_start=1
/product="Arc18p"
/protein_id="NP_013474.3"
/db_xref="GI:398366017"
/db_xref="SGD:S000004362"
/db_xref="GeneID:851085"
/translation="MPAYHSTFPVDPNTDRMVGNFALLPLNTKFRGPAYPSNSDYDII
DECLDLFRANSFFKNFEIKSPADRVLIYGILFINDCLAHLKITTSFNEAVKVLTNVAL
DNFTLPGTPGFPLNNVYQVPVQDHNSMDLLKTYIQQFRQELAMRLLERVYSSTDSKEY
PSKFWLAFTRRRFMNKSL"
gene 862714..866784
/gene="ROM2"
/locus_tag="YLR371W"
/db_xref="GeneID:851086"
mRNA 862714..866784
/gene="ROM2"
/locus_tag="YLR371W"
/product="Rom2p"
/transcript_id="NM_001182260.1"
/db_xref="GI:296146894"
/db_xref="GeneID:851086"
CDS 862714..866784
/gene="ROM2"
/locus_tag="YLR371W"
/note="GDP/GTP exchange factor (GEF) for Rho1p and Rho2p;
mutations are synthetically lethal with mutations in rom1,
which also encodes a GEF; Rom2p localization to the bud
surface is dependent on Ack1p"
/codon_start=1
/product="Rom2p"
/protein_id="NP_013475.1"
/db_xref="GI:6323403"
/db_xref="SGD:S000004363"
/db_xref="GeneID:851086"
/translation="MSETNVDSLGDRNDIYSQIFGVERRPDSFATFDSDSHGDISSQL
LPNRIENIQNLNVLLSEDIANDIIIAKQRRRSGVEAAIDDSDIPNNEMKGKSSNYILS
QQTNIKEVPDTQSLSSADNTPVSSPKKARDATSSHPIVHAKSMSHIYSTSNSASRQAK
HYNDHPLPPMSPRNEVYQKNKSTTAFVPKRKPSLPQLALAGLKKQSSFSTGSASTTPT
QARKSPLQGFGFFSRPSSKDLHEQHQHHQHIQHNNINNHNNNNTNNNGAHYQVGSSNS
NYPQHSHSISSRSMSLNSSTLKNIASSFQSKTSNSRKATQKYDITSNPFSDPHHHHHH
HHSSNSHSSLNNVHGSGNSSSVMGSSSNIGLGLKTRVSSTSLALKRYTSVSGTSLSSP
RRSSMTPLSASRPVMSASSKKPQVYPALLSRVATKFKSSIQLGEHKKDGLVYRDAFTG
QQAVDVICAIIRTSDRNLALLFGRSLDAQKLFHDVVYEHRLRDSPHEVYEFTDNSRFT
GTGSTNAHDPLMLLPNSSSFNSGNHSYPNSGMVPSSSTSSLNSDQATLTGSRLHMSSS
LSQQKNPAAIHNVNGVFTLLAECYSPTCTRDALCYSISCPRRLEQQARLNLKPNGGLK
RNISMALDDDDEEKPSWTSSVSKEDWENLPKKEIKRQEAIYEVYITEKNFVKSLEITR
DTFMKTLAETNIISADIRKNFIKHVFAHINDIYSVNRRFLKALTDRQRSSPVVRGIGD
IVLRFIPFFEPFVSYVASRPYAKYLIETQRSVNPYFARFDDDMMSSSLRHGIDSFLSQ
GVSRPGRYMLLVKEIMKSTDPEKDKSDYEDLSKAMDALRDFMKRIDQASGAAQDRHDV
KLLKQKILFKNEYVNLGLNDERRKIKHEGILSRKELSKSDGTVVGDIQFYLLDNMLLF
LKAKAVNKWHQHKVFQRPIPLPLLFACPGEDMPALRKYIGDHPDCSGTVIQPEYNTSN
PKNAITFLYYGAKQRYQVTLYAAQYAGLQTLLEKIKQGQAAIISKTEMFNVTKMSDRF
FDYTNKINSVTSCDGGRKLLIATNSGLYMSNIKRQQNKDHRHKSSAFFSTPIQLVQRN
NITQIAVLEEFKSIILLIDKKLYSCPLSLIEAEGNGTSFFKKHHKELINHVSFFAEGD
CNGKRLIVTAHSSSHSIKYFEHEHPLLAEKNGSGSGNKKSLKKKITEVIFDSEPVSIS
FLKANLCIGCKKGFQIVSISQNAHESLLDPADTSLEFALRDTLKPMAIYRVGNMFLLC
YTEFAFFVNNQGWRKKESHIIHWEGEPQKFAIWYPYILAFDSNFIEIRKIETGELIRC
VLADKIRLLQTSTQEILYCYEDYRGYDTVASLDFWG"
gene 867354..868391
/gene="SUR4"
/locus_tag="YLR372W"
/gene_synonym="APA1; ELO3; SRE1; VBM1"
/db_xref="GeneID:851087"
mRNA 867354..868391
/gene="SUR4"
/locus_tag="YLR372W"
/gene_synonym="APA1; ELO3; SRE1; VBM1"
/product="fatty acid elongase SUR4"
/transcript_id="NM_001182261.3"
/db_xref="GI:398366026"
/db_xref="GeneID:851087"
CDS 867354..868391
/gene="SUR4"
/locus_tag="YLR372W"
/gene_synonym="APA1; ELO3; SRE1; VBM1"
/note="Elongase, involved in fatty acid and sphingolipid
biosynthesis; synthesizes very long chain 20-26-carbon
fatty acids from C18-CoA primers; involved in regulation
of sphingolipid biosynthesis"
/codon_start=1
/product="fatty acid elongase SUR4"
/protein_id="NP_013476.3"
/db_xref="GI:398366027"
/db_xref="SGD:S000004364"
/db_xref="GeneID:851087"
/translation="MNTTTSTVIAAVADQFQSLNSSSSCFLKVHVPSIENPFGIELWP
IFSKVFEYFSGYPAEQFEFIHNKTFLANGYHAVSIIIVYYIIIFGGQAILRALNASPL
KFKLLFEIHNLFLTSISLVLWLLMLEQLVPMVYHNGLFWSICSKEAFAPKLVTLYYLN
YLTKFVELIDTVFLVLRRKKLLFLHTYHHGATALLCYTQLIGRTSVEWVVILLNLGVH
VIMYWYYFLSSCGIRVWWKQWVTRFQIIQFLIDLVFVYFATYTFYAHKYLDGILPNKG
TCYGTQAAAAYGYLILTSYLLLFISFYIQSYKKGGKKTVKKESEVSGSVASGSSTGVK
TSNTKVSSRKA"
gene complement(868662..871367)
/gene="VID22"
/locus_tag="YLR373C"
/db_xref="GeneID:851088"
mRNA complement(868662..871367)
/gene="VID22"
/locus_tag="YLR373C"
/product="Vid22p"
/transcript_id="NM_001182262.1"
/db_xref="GI:296146896"
/db_xref="GeneID:851088"
CDS complement(868662..871367)
/gene="VID22"
/locus_tag="YLR373C"
/note="Glycosylated integral membrane protein localized to
the plasma membrane; plays a role in
fructose-1,6-bisphosphatase (FBPase) degradation; involved
in FBPase transport from the cytosol to Vid (vacuole
import and degradation) vesicles"
/codon_start=1
/product="Vid22p"
/protein_id="NP_013477.1"
/db_xref="GI:6323405"
/db_xref="SGD:S000004365"
/db_xref="GeneID:851088"
/translation="MRAMDTQVQSAERGLVLPPMNSTVSSATAATTATNTDTDTDGDR
DEERESLAEDGSEWVPAYMLTRDRSRYLGHFLGVDKMLEAVKCKYCGVIIRRQGNSIS
MAEASQTHLWSTHKIDPNANYYSGWTGVEAGSTFMVRPPLKNHQGGSATTNSIANLLE
IDEDFLKRTREKEMALPLVQSLAIIIASENLPLSFVDNTAVRLLINQNANSLSFIDHD
LILNAIRSIAYNLDRIIQRTALRNNSDLSLIIDKNYLLMDPTDRSNQLSNRLKNQLFE
MQKINFFSLSHSVWNNTISILSIQYYDDFHSQVKTLPLIIQNLHEYNNDPKLSIPAQL
LKISQELPGLQNTVISITLPRSQIVDLLNVMDSQPFFPNTYTNAKNYYHNCIISIINS
AILPLFGTPKSADITHPRQSSFSKEPLTLLDSLIDLSNIDISNSIFSRINSFLDDLQS
NSWQLDKFRSLCEKFGFEFVCSKFDLSRYSTATVSLQTFLNLRPIIEEYQSSIQIEKF
NEIDFQIIDYLLITLNSINRILKFFTSSKSLNFTYVLFAIMSIEKHLLSTLGSLQFQR
LIAPFETFLSKIQEFKTILFSDDMNLLAMFLCPAILFEREVLEYSFHTISLSEIVDKL
STSIFSLLKRFLNLHTIGNVNNSHNTSNHSNMNIHTDNQTNNINNRSGNNSDNNDNEH
DNDNDNHSNSNTPASRIDIDPTGGENSVLPEQQPQNSNNNLSFGSLSDTHHLSDSTIS
KEIDSIFLQIIQEDLYDYLSTVNSIVPISYRSYCEQSNFIRDSGRFKKRIITEDSIIG
ELEQPMNFIEELLDIHVPVCNAFWSQYLDNDAGPIIRILFKIMQCQSSSSIRGEYSFL
NDFIPRVHPDLTQEIIKIKLFNDQFVASKVDYDLDTLQTASQYLP"
gene 871697..872728
/gene="STP3"
/locus_tag="YLR375W"
/db_xref="GeneID:851089"
mRNA 871697..872728
/gene="STP3"
/locus_tag="YLR375W"
/product="Stp3p"
/transcript_id="NM_001182264.3"
/db_xref="GI:398366032"
/db_xref="GeneID:851089"
CDS 871697..872728
/gene="STP3"
/locus_tag="YLR375W"
/note="Zinc-finger hypothetical protein, possibly involved
in pre-tRNA splicing and in uptake of branched-chain amino
acids"
/codon_start=1
/product="Stp3p"
/protein_id="NP_013479.3"
/db_xref="GI:398366033"
/db_xref="SGD:S000004367"
/db_xref="GeneID:851089"
/translation="MSNANNSAMNHITLPPISSFDNLIKAAERQYNGEASSASTHPTL
PNMNISNGSGSAGASSSMLSYQLLPHSNDVSRSNSSSSFLPSVQQPTEGSASASETSS
SASPSRSISPILKVAGPSSVGGAGVSTPHSTKINKPRKKKQCPICRNFYANLTTHKAT
HLTPEDRPHKCPICHRGFARNNDLLRHKKRHWKDEILSQSGVLSNHNDGKGGSVSPND
DDTHEKMTPMNSVTDYAQLKSLHQIKGTFKCPFNSTLIQLDMDMYPYKLKPLNFETSN
CHQTGVFSRCDTFKNHLKALHFEYPPGTKKKDRNVVPGRCKHCGLKFENVDVWLNEHV
GKQCGYKYH"
gene complement(872826..873554)
/gene="PSY3"
/locus_tag="YLR376C"
/db_xref="GeneID:851091"
mRNA complement(872826..873554)
/gene="PSY3"
/locus_tag="YLR376C"
/product="Psy3p"
/transcript_id="NM_001182265.1"
/db_xref="GI:296146898"
/db_xref="GeneID:851091"
CDS complement(872826..873554)
/gene="PSY3"
/locus_tag="YLR376C"
/note="Component of the Shu complex, which promotes
error-free DNA repair; Shu complex mediates inhibition of
Srs2p function; structural analysis reveals a similar
DNA-binding region in both Psy3p and Csm2p and that both
regions work together to form a single DNA binding site;
deletion of PSY3 results in a mutator phenotype; deletion
increases sensitivity to anticancer drugs oxaliplatin and
cisplatin but not mitomycin C"
/codon_start=1
/product="Psy3p"
/protein_id="NP_013480.1"
/db_xref="GI:6323408"
/db_xref="SGD:S000004368"
/db_xref="GeneID:851091"
/translation="MEVLKNIRIYPLSNFITSTKNYINLPNELRNLISEEQESKLGFL
HIIESDFKPSVALQKLVNCTTGDEKILIIDIVSIWSQQKQRQHGAIYMNSLSCINITG
LIVFLELLYDSPMDALRRCQVDNFNFQLRGIVIDNLSFLNFESDKNYDVINLSKFEKL
FKILRKLREFLGCWIITKSFPTDFYNGIENTLVDKWSIKRKSGVTLYPTKLPDSYMKG
MDLIIYREVVDGRPQYRRIAALEE"
gene complement(873746..874792)
/gene="FBP1"
/locus_tag="YLR377C"
/gene_synonym="ACN8"
/db_xref="GeneID:851092"
mRNA complement(873746..874792)
/gene="FBP1"
/locus_tag="YLR377C"
/gene_synonym="ACN8"
/product="fructose 1,6-bisphosphate 1-phosphatase"
/transcript_id="NM_001182266.3"
/db_xref="GI:398366040"
/db_xref="GeneID:851092"
CDS complement(873746..874792)
/gene="FBP1"
/locus_tag="YLR377C"
/gene_synonym="ACN8"
/EC_number="3.1.3.11"
/note="Fructose-1,6-bisphosphatase, key regulatory enzyme
in the gluconeogenesis pathway, required for glucose
metabolism; undergoes either proteasome-mediated or
autophagy-mediated degradation depending on growth
conditions; interacts with Vid30p"
/codon_start=1
/product="fructose 1,6-bisphosphate 1-phosphatase"
/protein_id="NP_013481.3"
/db_xref="GI:398366041"
/db_xref="SGD:S000004369"
/db_xref="GeneID:851092"
/translation="MPTLVNGPRRDSTEGFDTDIITLPRFIIEHQKQFKNATGDFTLV
LNALQFAFKFVSHTIRRAELVNLVGLAGASNFTGDQQKKLDVLGDEIFINAMRASGII
KVLVSEEQEDLIVFPTNTGSYAVCCDPIDGSSNLDAGVSVGTIASIFRLLPDSSGTIN
DVLRCGKEMVAACYAMYGSSTHLVLTLGDGVDGFTLDTNLGEFILTHPNLRIPPQKAI
YSINEGNTLYWNETIRTFIEKVKQPQADNNNKPFSARYVGSMVADVHRTFLYGGLFAY
PCDKKSPNGKLRLLYEAFPMAFLMEQAGGKAVNDRGERILDLVPSHIHDKSSIWLGSS
GEIDKFLDHIGKSQ"
STS 874615..874792
/standard_name="px-25g9"
/db_xref="UniSTS:257475"
gene 875376..875471
/locus_tag="tK(UUU)L"
/db_xref="GeneID:851093"
tRNA join(875376..875412,875436..875471)
/locus_tag="tK(UUU)L"
/product="tRNA-Lys"
/note="Lysine tRNA (tRNA-Lys), predicted by tRNAscan-SE
analysis; thiolation of uridine at wobble position (34)
requires Ncs6p"
/db_xref="SGD:S000006633"
/db_xref="GeneID:851093"
gene complement(875736..877178)
/gene="SEC61"
/locus_tag="YLR378C"
/db_xref="GeneID:851095"
mRNA complement(875736..877178)
/gene="SEC61"
/locus_tag="YLR378C"
/product="Sec61p"
/transcript_id="NM_001182267.1"
/db_xref="GI:296146900"
/db_xref="GeneID:851095"
CDS complement(875736..877178)
/gene="SEC61"
/locus_tag="YLR378C"
/note="Essential subunit of Sec61 complex (Sec61p, Sbh1p,
and Sss1p); forms a channel for SRP-dependent protein
import and retrograde transport of misfolded proteins out
of the ER; with Sec63 complex allows SRP-independent
protein import into ER"
/codon_start=1
/product="Sec61p"
/protein_id="NP_013482.1"
/db_xref="GI:6323411"
/db_xref="SGD:S000004370"
/db_xref="GeneID:851095"
/translation="MSSNRVLDLFKPFESFLPEVIAPERKVPYNQKLIWTGVSLLIFL
ILGQIPLYGIVSSETSDPLYWLRAMLASNRGTLLELGVSPIITSSMIFQFLQGTQLLQ
IRPESKQDRELFQIAQKVCAIILILGQALVVVMTGNYGAPSDLGLPICLLLIFQLMFA
SLIVMLLDELLSKGYGLGSGISLFTATNIAEQIFWRAFAPTTVNSGRGKEFEGAVIAF
FHLLAVRKDKKRALVEAFYRTNLPNMFQVLMTVAIFLFVLYLQGFRYELPIRSTKVRG
QIGIYPIKLFYTSNTPIMLQSALTSNIFLISQILFQKYPTNPLIRLIGVWGIRPGTQG
PQMALSGLAYYIQPLMSLSEALLDPIKTIVYITFVLGSCAVFSKTWIEISGTSPRDIA
KQFKDQGMVINGKRETSIYRELKKIIPTAAAFGGATIGALSVGSDLLGTLGSGASILM
ATTTIYGYYEAAAKEGGFTKNLVPGFSDLM"
gene 878282..879508
/gene="CSR1"
/locus_tag="YLR380W"
/gene_synonym="SFH2"
/db_xref="GeneID:851096"
mRNA 878282..879508
/gene="CSR1"
/locus_tag="YLR380W"
/gene_synonym="SFH2"
/product="Csr1p"
/transcript_id="NM_001182269.3"
/db_xref="GI:398366044"
/db_xref="GeneID:851096"
CDS 878282..879508
/gene="CSR1"
/locus_tag="YLR380W"
/gene_synonym="SFH2"
/note="Phosphatidylinositol transfer protein; has a
potential role in regulating lipid and fatty acid
metabolism under heme-depleted conditions; interacts
specifically with thioredoxin peroxidase; may have a role
in oxidative stress resistance; protein abundance
increases in response to DNA replication stress"
/codon_start=1
/product="Csr1p"
/protein_id="NP_013484.3"
/db_xref="GI:398366045"
/db_xref="SGD:S000004372"
/db_xref="GeneID:851096"
/translation="MSFDRQLTEDQEVVLKQIWTHLFHLWQVPVDGTHIFPNNSLHSS
STPAKKKKSSWFSKLQSSDHTQDSSEAAEAAHLYEKGKIHKALANLDPQTTKKQFWHD
IKNETPDATILKFIRARKWNADKTIAMLGHDLYWRKDTINKIINGGERAVYENNETGV
IKNLELQKATIQGYDNDMRPVILVRPRLHHSSDQTEQELEKFSLLVIEQSKLFFKENY
PASTTILFDLNGFSMSNMDYAPVKFLITCFEAHYPESLGHLLIHKAPWIFNPIWNIIK
NWLDPVVASKIVFTKNIDELHKFIQPQYIPRYLGGENDNDLDHYTPPDGSLDVHLKDT
ETRAMIEKEREELVEQFLTVTAQWIEHQPLNDPAYIQLQEKRVQLSTALCENYSKLDP
YIRSRSVYDYNGSLKV"
gene 879723..881924
/gene="CTF3"
/locus_tag="YLR381W"
/gene_synonym="CHL3"
/db_xref="GeneID:851097"
mRNA 879723..881924
/gene="CTF3"
/locus_tag="YLR381W"
/gene_synonym="CHL3"
/product="Ctf3p"
/transcript_id="NM_001182270.1"
/db_xref="GI:296146902"
/db_xref="GeneID:851097"
CDS 879723..881924
/gene="CTF3"
/locus_tag="YLR381W"
/gene_synonym="CHL3"
/note="Outer kinetochore protein that forms a complex with
Mcm16p and Mcm22p; may bind the kinetochore to spindle
microtubules; orthologous to human centromere
constitutive-associated network (CCAN) subunit CENP-I and
fission yeast mis6"
/codon_start=1
/product="Ctf3p"
/protein_id="NP_013485.1"
/db_xref="GI:6323413"
/db_xref="SGD:S000004373"
/db_xref="GeneID:851097"
/ 