GenomeNet

Database: RefSeq
Entry: NC_001144
LinkDB: NC_001144
Original site: NC_001144 
LOCUS       NC_001144            1078177 bp    DNA     linear   PLN 22-AUG-2014
DEFINITION  Saccharomyces cerevisiae S288c chromosome XII, complete sequence.
ACCESSION   NC_001144
VERSION     NC_001144.5  GI:330443681
DBLINK      BioProject: PRJNA128
KEYWORDS    RefSeq; TPA:inferential.
SOURCE      Saccharomyces cerevisiae S288c
  ORGANISM  Saccharomyces cerevisiae S288c
            Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina;
            Saccharomycetes; Saccharomycetales; Saccharomycetaceae;
            Saccharomyces.
REFERENCE   1  (bases 1 to 1078177)
  AUTHORS   Johnston,M., Hillier,L., Riles,L., Albermann,K., Andre,B.,
            Ansorge,W., Benes,V., Bruckner,M., Delius,H., Dubois,E.,
            Dusterhoft,A., Entian,K.D., Floeth,M., Goffeau,A., Hebling,U.,
            Heumann,K., Heuss-Neitzel,D., Hilbert,H., Hilger,F., Kleine,K.,
            Kotter,P., Louis,E.J., Messenguy,F., Mewes,H.W., Hoheisel,J.D. et
            al.
  TITLE     The nucleotide sequence of Saccharomyces cerevisiae chromosome XII
  JOURNAL   Nature 387 (6632 SUPPL), 87-90 (1997)
   PUBMED   9169871
REFERENCE   2  (bases 1 to 1078177)
  AUTHORS   Goffeau,A., Barrell,B.G., Bussey,H., Davis,R.W., Dujon,B.,
            Feldmann,H., Galibert,F., Hoheisel,J.D., Jacq,C., Johnston,M.,
            Louis,E.J., Mewes,H.W., Murakami,Y., Philippsen,P., Tettelin,H. and
            Oliver,S.G.
  TITLE     Life with 6000 genes
  JOURNAL   Science 274 (5287), 546 (1996)
   PUBMED   8849441
REFERENCE   3  (bases 1 to 1078177)
  CONSRTM   NCBI Genome Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-AUG-2014) National Center for Biotechnology
            Information, NIH, Bethesda, MD 20894, USA
REFERENCE   4  (bases 1 to 1078177)
  CONSRTM   Saccharomyces Genome Database
  TITLE     Direct Submission
  JOURNAL   Submitted (06-FEB-2013) Department of Genetics, Stanford
            University, Stanford, CA, USA
  REMARK    Protein update by submitter
REFERENCE   5  (bases 1 to 1078177)
  CONSRTM   Saccharomyces Genome Database
  TITLE     Direct Submission
  JOURNAL   Submitted (04-MAY-2012) Department of Genetics, Stanford
            University, Stanford, CA, USA
  REMARK    Protein update by submitter
REFERENCE   6  (bases 1 to 1078177)
  CONSRTM   Saccharomyces Genome Database
  TITLE     Direct Submission
  JOURNAL   Submitted (31-MAR-2011) Department of Genetics, Stanford
            University, Stanford, CA, USA
  REMARK    Sequence update by submitter
REFERENCE   7  (bases 1 to 1078177)
  CONSRTM   Saccharomyces Genome Database
  TITLE     Direct Submission
  JOURNAL   Submitted (14-DEC-2009) Department of Genetics, Stanford
            University, Stanford, CA, USA
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence is identical to BK006945.
            On Apr 26, 2011 this sequence version replaced gi:85666119.
            Sequence assembly version R64-1-1.
            COMPLETENESS: full length.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-6119              Z73172.1           1-6119
            3011-11725          Z73171.1           1-8715
            9837-13082          Z73170.1           1-3246
            9837-13082          Z73170.1           1-3246
            12048-14647         Z73169.1           1-2600
            13446-16638         Z73168.1           1-3193
            16073-17955         Z73167.1           1-1883
            17614-21137         Z73166.1           1-3524
            19708-22473         Z73165.1           1-2766
            21840-23568         Z73164.1           1-1729
            22981-25755         Z73163.1           1-2775
            25297-27408         Z73162.1           1-2112
            26995-30108         Z73161.1           1-3114
            28306-32893         Z73160.1           1-4588
            31705-35502         Z73159.1           1-3797
            35205-37332         Z73158.1           1-2128
            36362-39803         Z73156.1           1-3442
            39472-40665         Z73155.1           1-1194
            40415-41279         Z73154.1           1-865
            41206-46671         Z73153.1           1-5466
            46266-47858         Z73152.1           1-1593
            47464-49937         Z73150.1           1-2474
            48663-52086         Z73148.1           1-3424
            51948-53130         Z73147.1           1-1183
            52591-54210         Z73146.1           1-1620
            53932-64061         Z73145.1           1-10130
            59566-65774         Z73144.1           1-6209
            65208-66561         Z73143.1           1-1354
            66519-68579         Z73142.1           1-2061
            68257-70632         Z73140.1           1-2376
            70479-73408         Z73139.1           1-2930
            73147-74269         Z73138.1           1-1123
            74102-77151         Z73137.1           1-3050
            76748-80355         Z73136.1           1-3608
            80206-81460         Z73135.1           1-1255
            80698-84803         Z73134.1           1-4106
            83711-87402         Z73133.1           1-3692
            86565-88622         Z73132.1           1-2058
            88156-94746         Z73131.1           1-6591
            90866-95565         Z73130.1           1-4700
            95122-97996         Z73129.1           1-2875
            97486-99043         Z73128.1           1-1558
            98837-100946        Z73127.1           1-2110
            100202-105555       Z73126.1           1-5354
            105348-109901       Z73125.1           1-4554
            106173-112233       Z73123.1           1-6061
            111333-112846       Z73122.1           1-1514
            112546-116431       Z73121.1           1-3886
            115994-121321       Z73120.1           1-5328
            121112-122074       Z73119.1           1-963
            121649-125533       Z73118.1           1-3885
            122409-127522       Z73117.1           1-5114
            127256-129329       Z73116.1           1-2074
            128993-131204       Z73115.1           1-2212
            130614-131728       Z73114.1           1-1115
            131415-134301       Z73113.1           1-2887
            133988-136585       Z73112.1           1-2598
            136263-137939       Z73111.1           1-1677
            137867-141072       Z73110.1           1-3206
            140547-143200       Z73109.1           1-2654
            142924-146290       Z73108.1           1-3367
            146042-147889       Z73107.1           1-1848
            147602-151388       Z73106.1           1-3787
            150164-154342       Z73173.1           1-4179
            153978-156854       Z73174.1           1-2877
            156335-157933       Z73175.1           1-1599
            157731-160048       Z73176.1           1-2318
            159506-161754       Z73177.1           1-2249
            161435-164391       Z73178.1           1-2957
            163894-165576       Z73179.1           1-1683
            165403-166536       Z73180.1           1-1134
            166084-167319       Z73181.1           1-1236
            167137-169102       Z73182.1           1-1966
            167803-169981       Z73183.1           1-2179
            169679-171338       Z73184.1           1-1660
            170351-172267       Z73185.1           1-1917
            171765-175226       Z73186.1           1-3462
            174983-176801       Z73187.1           1-1819
            176745-177607       Z73188.1           1-863
            177417-178706       Z73189.1           1-1290
            178622-180287       Z73190.1           1-1666
            179100-181788       Z73191.1           1-2689
            181482-183622       Z73192.1           1-2141
            183406-184173       Z73193.1           1-768
            184163-185497       Z73194.1           1-1335
            184927-187662       Z73195.1           1-2738
            187130-194451       Z73196.1           1-7324
            193282-195449       Z73197.1           1-2168
            195175-196828       Z73198.1           1-1654
            196473-199649       Z73199.1           1-3177
            198128-201975       Z73200.1           1-3848
            201316-203289       Z73201.1           1-1974
            202591-204224       Z73202.1           1-1634
            204082-204990       Z73203.1           1-909
            204786-208760       Z73204.1           1-3975
            208501-210511       Z73205.1           1-2011
            210270-212368       Z73206.1           1-2099
            211934-221520       Z73207.1           1-9587
            214457-222684       Z73208.1           1-8228
            222133-224920       Z73209.1           1-2788
            223060-225425       Z73210.1           1-2366
            225173-228907       Z73211.1           1-3735
            228597-229965       Z73212.1           1-1369
            229698-231701       Z73214.1           1-2004
            230452-232389       Z73215.1           1-1938
            232014-235036       Z73216.1           1-3023
            233665-238000       Z73217.1           1-4336
            237704-239346       Z73218.1           1-1643
            238814-242231       Z73219.1           1-3418
            241408-243885       Z73220.1           1-2478
            243353-245586       Z73221.1           1-2234
            245173-246323       Z73222.1           1-1151
            246073-247200       Z73223.1           1-1128
            246978-248099       Z73224.1           1-1122
            247954-248716       Z73225.1           1-763
            248427-251271       Z73226.1           1-2845
            250256-253860       Z73227.1           1-3605
            253081-255305       Z73228.1           1-2225
            254959-257991       Z73229.1           1-3033
            257358-259737       Z73230.1           1-2380
            259402-260978       Z73231.1           1-1577
            260548-263193       Z73232.1           1-2646
            262767-264156       Z73233.1           1-1390
            263955-265455       Z73235.1           1-1501
            265255-266372       Z73236.1           1-1118
            266278-267168       Z73237.1           1-891
            266919-267812       Z73238.1           1-894
            267724-271007       Z73239.1           1-3284
            269058-271629       Z73240.1           1-2572
            271464-274140       Z73241.1           1-2677
            273916-275377       Z73242.1           1-1462
            275212-278861       Z73243.1           1-3650
            278627-281018       Z73244.1           1-2392
            280944-281955       Z73245.1           1-1012
            281622-282926       Z73246.1           1-1305
            282457-283871       Z73247.1           1-1415
            283608-285735       Z73249.1           1-2128
            284276-326297       U53880.1           1-42022
            325098-365437       U53876.1           1-40340
            343768-346584       Z73275.1           1-2817
            346585-364937       "ATGA...ATTT"      1-18353
            364938-380630       U53878.1           1-15693
            371211-374943       Z73285.1           1-3733
            374944-379430       "TCAT...GATT"      1-4487
            379431-402653       U53877.1           1-23223
            400654-429807       U53881.1           1-29154
            429608-468929       U53879.1           1-39322
            447576-460166       Z73326.1           1-12591
            460167-468810       "GTAG...ACTA"      1-8644
            468811-498236       U51921.1           1-29427
            497837-538574       U17246.1           1-40738
            538375-577244       U14913.2           1-38870
            576245-617698       U19027.1           1-41454
            617299-657753       U20865.1           1-40455
            654754-687247       U17244.1           1-32494
            686048-700874       U17245.1           1-14827
            699875-740088       U17243.1           1-40214
            738089-757286       U17247.1           1-19198
            754987-792716       U20618.2           1-37728
            792517-830058       U19028.1           1-37541
            829459-844633       U19102.1           1-15175
            844234-876039       U19103.1           1-31806
            875040-897799       U19104.1           1-22761
            897400-937600       U19729.2           1-40198
            936801-964950       U20162.1           1-28149
            964551-1000355      U20939.1           1-35805
            997856-1022616      U21094.1           1-24761
            1022417-1044147     U22382.1           1-21732
            1043948-1073581     U22383.1           1-29634
            1072246-1078177     Z73327.1           1-5932
FEATURES             Location/Qualifiers
     source          1..1078177
                     /organism="Saccharomyces cerevisiae S288c"
                     /mol_type="genomic DNA"
                     /strain="S288c"
                     /db_xref="taxon:559292"
                     /chromosome="XII"
     telomere        complement(1..12085)
                     /note="TEL12L; Telomeric region on the left arm of
                     Chromosome XII; composed of an X element core sequence, X
                     element combinatorial repeats, and three distinct regions
                     of telomeric repeats separated by two short Y' elements"
                     /db_xref="SGD:S000028910"
     repeat_region   complement(1..75)
                     /note="TEL12L-TR1; Terminal telomeric repeats on the left
                     arm of Chromosome XII"
                     /rpt_family="Telomeric Repeat"
                     /db_xref="SGD:S000028911"
     repeat_region   complement(76..5661)
                     /note="TEL12L-YP1; Short telomeric Y' element on the left
                     arm of Chromosome XII; more end-proximal of two two short
                     telomeric Y' elements; contains an ARS consensus sequence,
                     a region of 36-bp repeats, and two ORFs YLL067C and
                     YLL067W-A"
                     /rpt_family="Y' element"
                     /db_xref="SGD:S000028916"
     gene            complement(<585..>4301)
                     /locus_tag="YLL067C"
                     /db_xref="GeneID:850659"
     mRNA            complement(join(<585..3915,4015..>4301))
                     /locus_tag="YLL067C"
                     /product="Y' element ATP-dependent helicase"
                     /transcript_id="NM_001181887.1"
                     /db_xref="GI:296146478"
                     /db_xref="GeneID:850659"
     CDS             complement(join(585..3915,4015..4301))
                     /locus_tag="YLL067C"
                     /EC_number="3.6.4.12"
                     /note="Putative Y' element ATP-dependent helicase"
                     /codon_start=1
                     /product="Y' element ATP-dependent helicase"
                     /protein_id="NP_013033.1"
                     /db_xref="GI:6322961"
                     /db_xref="SGD:S000003990"
                     /db_xref="GeneID:850659"
                     /translation="MRTFTDFVSGAPIVRSLQKSTIRRYGYNLAPHMFLLLHVDELSI
                     FSAYQASLPGEKKVDTERLKRDLCPRKPIEIKYFSQICNDMMNKKDRLGDVLATAQRI
                     RRRYNKNGSSEPRLKTLDGLTSERWIQWLGLESDYHCSFSSTRNAEDVVAGEAASSDH
                     DQKISRVTRKRPREPKSTNDILVAGQKLFGSSFEFRDLHQLRLCHEIYMADTPSVAVQ
                     APPGYGKTELFHLPLIALASKGDVKYVSFLFVPYTVLLANCMIRLGRCGCLNVAPVRN
                     FIEEGCDGVTDLYVGIYDDLASTNFTDRIAAWENIVECTFRTNNVKLGYLIVDEFHNF
                     ETEVYRQSQFGGITNLDFDAFEKAIFLSGTAPEAVADAALQRIGLTGLAKKSMDINEL
                     KRSEDLSRGLSSYPTRMFNLIKEKSEVPLGHVHKIWKKVESQPEEALKLLLALFEIEP
                     ESKAIVVASTTNEVEELACSWRKYFRVVWIHGKLGAAEKVSRTKEFVTDGSMRVLIGT
                     KLVTEGIDIKQLMMVIMLDNRLNIIELIQGVGRLRDGGLCYLLSRKNSWAARNRKGEL
                     PPIKEGCITEQVREFYGLESKKGKKGQHVGCCGSRTDLSADTVELIERMDRLAEKQAT
                     ASMSIVALPSSFQESNSSDRCRKYCSSDEDSNTCIHGSANASTNATTNSSTNATTTAS
                     TNVRTSATTTASINVRTSATTTESTNSSTNATTTASTNVRTSATTTASINVRTSATTT
                     ESTNSNTSATTTESTDSNTSATTTESTDSSTNATTTASINVRTSATTTESTNSNTNAT
                     TTESTNSSTNATTTEGTNSNTSATTTASTNSSTNATTTESTNASAKEDANKDGNAEDN
                     RFHPVTDINKESYKRKGSQMVLLERKKLKAQFPNTSENMNVLQFLGFRSDEIKHLFLY
                     GIDVYFCPEGVFTQYGLCKGCQKMFELCVCWAGQKVSYRRMAWEALAVERMLRNDEEY
                     KEYLEDIEPYHGDPVGYLKFFSVKRGEIYSQIQRNYAWYLAITRRRETISVLDSTRGK
                     QGSQVFRMSGRQIKELYYKVWSNLRESKTEVLQYFLNWDEKKCREEWEAKDDTVFVEA
                     LEKVGVFQRLRSMTSAGLQGPQYVKLQFSRHHRQLRSRYELSLGMHLRDQLALGVTPS
                     KVPHWTAFLSMLIGLFYNKTFRQKLEYLLEQISEVWLLPHWVDLANVEVLAADNTRVP
                     C"
     gene            <5605..>5775
                     /locus_tag="YLL066W-B"
                     /db_xref="GeneID:1466404"
     mRNA            <5605..>5775
                     /locus_tag="YLL066W-B"
                     /product="hypothetical protein"
                     /transcript_id="NM_001184605.1"
                     /db_xref="GI:296146479"
                     /db_xref="GeneID:1466404"
     CDS             5605..5775
                     /locus_tag="YLL066W-B"
                     /note="hypothetical protein; overexpression causes a cell
                     cycle delay or arrest"
                     /codon_start=1
                     /product="hypothetical protein"
                     /protein_id="NP_878115.1"
                     /db_xref="GI:33438827"
                     /db_xref="SGD:S000028672"
                     /db_xref="GeneID:1466404"
                     /translation="MSLRPCLTPSSMQYSDIYIHHTHTPHPHHTHTHTHHTPTHSLTS
                     TFTLAVTPYPAF"
     repeat_region   complement(5662..5723)
                     /note="TEL12L-TR2; Middle stretch of telomeric repeats on
                     the left arm of Chromosome XII"
                     /rpt_family="Telomeric Repeat"
                     /db_xref="SGD:S000028912"
     repeat_region   complement(5724..11196)
                     /note="TEL12L-YP2; Short Y' element in the left telomere
                     of Chromosome XII; more centromere-proximal of two short
                     Y' elements; contains an ARS consensus sequence, a region
                     of 36-bp repeats, and two ORFs YLL066C and YLL066W-A"
                     /rpt_family="Y' element"
                     /db_xref="SGD:S000028917"
     gene            complement(<6120..>9836)
                     /locus_tag="YLL066C"
                     /db_xref="GeneID:850660"
     mRNA            complement(join(<6120..9450,9550..>9836))
                     /locus_tag="YLL066C"
                     /product="Y' element ATP-dependent helicase"
                     /transcript_id="NM_001181886.1"
                     /db_xref="GI:296146480"
                     /db_xref="GeneID:850660"
     CDS             complement(join(6120..9450,9550..9836))
                     /locus_tag="YLL066C"
                     /EC_number="3.6.4.12"
                     /note="Putative Y' element ATP-dependent helicase; YLL066C
                     is not an essential gene"
                     /codon_start=1
                     /product="Y' element ATP-dependent helicase"
                     /protein_id="NP_013034.1"
                     /db_xref="GI:6322962"
                     /db_xref="SGD:S000003989"
                     /db_xref="GeneID:850660"
                     /translation="MRTFTDFVSGAPIVRSLQKSTIRRYGYNLAPHMFLLLHVDELSI
                     FSAYQASLPGEKKVDTERLKRDLCPRKPIEIKYFSQICNDMMNKKDRLGDVLATAQRI
                     RRRYNKNGSSEPRLKTLDGLTSERWIQWLGLESDYHCSFSSTRNAEDVVAGEAASSDH
                     DQKISRVTRKRPREPKSTNDILVAGQKLFGSSFEFRDLHQLRLCHEIYMADTPSVAVQ
                     APPGYGKTELFHLPLIALASKGDVKYVSFLFVPYTVLLANCMIRLGRCGCLNVAPVRN
                     FIEEGCDGVTDLYVGIYDDLASTNFTDRIAAWENIVECTFRTNNVKLGYLIVDEFHNF
                     ETEVYRQSQFGGITNLDFDAFEKAIFLSGTAPEAVADAALQRIGLTGLAKKSMDINEL
                     KRSEDLSRGLSSYPTRMFNLIKEKSEVPLGHVHKIWKKVESQPEEALKLLLALFEIEP
                     ESKAIVVASTTNEVEELACSWRKYFRVVWIHGKLGAAEKVSRTKEFVTDGSMRVLIGT
                     KLVTEGIDIKQLMMVIMLDNRLNIIELIQGVGRLRDGGLCYLLSRKNSWAARNRKGEL
                     PPIKEGCITEQVREFYGLESKKGKKGQHVGCCGSRTDLSADTVELIERMDRLAEKQAT
                     ASMSIVALPSSFQESNSSDRCRKYCSSDEDSNTCIHGSANASTNATTNSSTNATTTAS
                     TNVRTSATTTASINVRTSATTTESTNSSTNATTTASTNVRTSATTTASINVRTSATTT
                     ESTNSNTSATTTESTDSNTSATTTESTDSNTSATTTASTNSSTNATTTASTNSSTNAT
                     TTESTNASAKEDANKDGNAEDNRFHPVTDINKESYKRKGSQMVLLERKKLKAQFPNTS
                     ENMNVLQFLGFRSDEIKHLFLYGIDIYFCPEGVFTQYGLCKGCQKMFGLCVCWAGQKV
                     SYRRMAWEALAVERMLRNDEEYKEYLEDIEPYHGDPVGYLKFFSVKRGEIYSQIQRNY
                     AWYLAITRRRETISVLDSTRGKQGSQVFRMSGRQIKELYYKVWSNLRESKTEVLQYFL
                     NWDEKKCREEWEAKDDTVFVEALEKVGVFQRLRSMTSAGLQGPQYVKLQFSRHHRQLR
                     SRYELSLGMHLRDQLALGVTPSKVPHWTAFLSMLIGLFYNKTFRQKLEYLLEQISEVW
                     LLPHWVDLANVEVLAADNTRVPLYMLMVAVHKELDSDDVPDGRFDIILLCRDSSREVG
                     E"
     repeat_region   complement(11197..11358)
                     /note="TEL12L-TR3; Internal telomeric repeats on the left
                     arm of Chromosome XII"
                     /rpt_family="Telomeric Repeat"
                     /db_xref="SGD:S000028913"
     repeat_region   complement(11359..11625)
                     /note="TEL12L-XR; Telomeric X element combinatorial repeat
                     on the left arm of Chr XII; contains repeats of the D, C,
                     B and A types, as well as Tbf1p binding sites; formerly
                     called SubTelomeric Repeats"
                     /rpt_family="X element Combinatorial Repeats"
                     /db_xref="SGD:S000028915"
     repeat_region   complement(11626..12085)
                     /note="TEL12L-XC; Telomeric X element Core sequence on the
                     left arm of Chromosome XII; contains an ARS consensus
                     sequence, an Abf1p binding site consensus sequence, and
                     ORF YLL065W"
                     /rpt_family="X element Core sequence"
                     /db_xref="SGD:S000028914"
     gene            complement(<13083..>13445)
                     /gene="PAU18"
                     /locus_tag="YLL064C"
                     /db_xref="GeneID:850662"
     mRNA            complement(<13083..>13445)
                     /gene="PAU18"
                     /locus_tag="YLL064C"
                     /product="Pau18p"
                     /transcript_id="NM_001181884.1"
                     /db_xref="GI:296146481"
                     /db_xref="GeneID:850662"
     CDS             complement(13083..13445)
                     /gene="PAU18"
                     /locus_tag="YLL064C"
                     /note="hypothetical protein; member of the seripauperin
                     multigene family encoded mainly in subtelomeric regions;
                     identical to Pau6p"
                     /codon_start=1
                     /product="Pau18p"
                     /protein_id="NP_013036.1"
                     /db_xref="GI:6322964"
                     /db_xref="SGD:S000003987"
                     /db_xref="GeneID:850662"
                     /translation="MVKLTSIAAGVAAIAATASATTTLAQSDERVNLVELGVYVSDIR
                     AHLAQYYMFQAAHPTETYPVEVAEAVFNYGDFTTMLTGIAPDQVTRMITGVPWYSTRL
                     KPAISKALSKDGIYTIAN"
     gene            complement(<14648..>16072)
                     /gene="AYT1"
                     /locus_tag="YLL063C"
                     /db_xref="GeneID:850663"
     mRNA            complement(<14648..>16072)
                     /gene="AYT1"
                     /locus_tag="YLL063C"
                     /product="Ayt1p"
                     /transcript_id="NM_001181883.1"
                     /db_xref="GI:296146482"
                     /db_xref="GeneID:850663"
     CDS             complement(14648..16072)
                     /gene="AYT1"
                     /locus_tag="YLL063C"
                     /EC_number="2.3.1.-"
                     /note="Acetyltransferase; catalyzes trichothecene
                     3-O-acetylation, suggesting a possible role in
                     trichothecene biosynthesis"
                     /codon_start=1
                     /product="Ayt1p"
                     /protein_id="NP_013037.1"
                     /db_xref="GI:6322965"
                     /db_xref="SGD:S000003986"
                     /db_xref="GeneID:850663"
                     /translation="MFRVKIISQKRTKSVQMLENDQLDILGQQPSLYKLYTQICSIYR
                     VPDPSAHDHIVNTLTRGLETLAKNFQWLAGNVVNEGADEGNTGTYRIVPSDKIPLIVQ
                     DLREDLSAPTMDSLEKADFPIYMLDEKTFAPCMTINPPGNTIGMAAKSGPVFAVQANF
                     ISGGLVLTIVGQHNIMDITGQESIINLLNKSCHQKPFSDEELLIGNIDKSKSIPLFDE
                     TWEPDTTLVHEIVETSRNTSGEEKEQSCSSNSTWAYVEFSAISLQNLRILAMQTCTSG
                     TKFVSTDDIVTAFIWKSVSRARLSRLKPETKSNLGRAVDVRKRLGLPETYPGLLVNMT
                     FNTGSLKSLDHKSLGVLASQIRRKLDPKVFDLAYNTCALATLLSRCPDKTKVSIPQPI
                     DTLSGIMVSSWAKVSLYDVDFNLGLGKPKSVRRPRFISLESLIYFMPRSSRGEMVVAL
                     CLRDKDWECLNADKEWTNYATHIG"
     gene            complement(<16639..>17613)
                     /gene="MHT1"
                     /locus_tag="YLL062C"
                     /db_xref="GeneID:850664"
     mRNA            complement(<16639..>17613)
                     /gene="MHT1"
                     /locus_tag="YLL062C"
                     /product="Mht1p"
                     /transcript_id="NM_001181882.1"
                     /db_xref="GI:296146483"
                     /db_xref="GeneID:850664"
     CDS             complement(16639..17613)
                     /gene="MHT1"
                     /locus_tag="YLL062C"
                     /EC_number="2.1.1.10"
                     /note="S-methylmethionine-homocysteine methyltransferase;
                     functions along with Sam4p in the conversion of
                     S-adenosylmethionine (AdoMet) to methionine to control the
                     methionine/AdoMet ratio"
                     /codon_start=1
                     /product="Mht1p"
                     /protein_id="NP_013038.1"
                     /db_xref="GI:6322966"
                     /db_xref="SGD:S000003985"
                     /db_xref="GeneID:850664"
                     /translation="MKRIPIKELIVEHPGKVLILDGGQGTELENRGININSPVWSAAP
                     FTSESFWEPSSQERKVVEEMYRDFMIAGANILMTITYQANFQSISENTSIKTLAAYKR
                     FLDKIVSFTREFIGEERYLIGSIGPWAAHVSCEYTGDYGPHPENIDYYGFFKPQLENF
                     NQNRDIDLIGFETIPNFHELKAILSWDEDIISKPFYIGLSVDDNSLLRDGTTLEEISV
                     HIKGLGNKINKNLLLMGVNCVSFNQSALILKMLHEHLPGMPLLVYPNSGEIYNPKEKT
                     WHRPTNKLDDWETTVKKFVDNGARIIGGCCRTSPKDIAEIASAVDKYS"
     gene            <17956..>19707
                     /gene="MMP1"
                     /locus_tag="YLL061W"
                     /db_xref="GeneID:850665"
     mRNA            <17956..>19707
                     /gene="MMP1"
                     /locus_tag="YLL061W"
                     /product="S-methylmethionine permease MMP1"
                     /transcript_id="NM_001181881.1"
                     /db_xref="GI:296146484"
                     /db_xref="GeneID:850665"
     CDS             17956..19707
                     /gene="MMP1"
                     /locus_tag="YLL061W"
                     /note="High-affinity S-methylmethionine permease; required
                     for utilization of S-methylmethionine as a sulfur source;
                     has similarity to S-adenosylmethionine permease Sam3p"
                     /codon_start=1
                     /product="S-methylmethionine permease MMP1"
                     /protein_id="NP_013039.1"
                     /db_xref="GI:6322967"
                     /db_xref="SGD:S000003984"
                     /db_xref="GeneID:850665"
                     /translation="MDEFESTKLSKVQFSTSVLSTPSNEGNNLIHRFKNSFKRNDSPA
                     IQEGLLYSELSEEEKIQWDLANQPYKKVLDQRHLTMIAIGGTLGTGLFIGLGESLASG
                     PASLLIGFLLVGASMLCVVQCGAELSCQYPVSGSYALHASRFIDPSVGFSIGINYLLM
                     WLISYPSELVGCSLTISYWAPSVNPAAWVAIAFVLSMLLNLFGARGFAESEFYMSIFK
                     IVALFIFIIIGIVLIAGGGPDSTGYIGTKYWHDPGSFAVPVFKNLCNTFVSAAYSFSG
                     TEMVVLTSTEARSVSSVSRAAKGTFWRIIIFYIVTVIIIGCLVPYNDPRLISGSSSED
                     ITASPFVIALSNTGAMGTRVSHFMNAVILIAVFSVCNSCVYASSRLIQGLATAGQLPK
                     ICAYMDRNGRPLVGMAICGAFGLLGFLVVSKNQGTVFTWLFALCSISFFTTWFCICFC
                     QVRFRMAMKAQGRSKDDIIYRSTLGIYGGIFGCILNVLLVIGEIYVSAAPVGSPSSAA
                     NFFEYCMSIPIMIAVYIGHRIYRRDWRHWYIKRMDIDLDSGHSLEDFEATKLERDEDK
                     KYVSSKPLYYRIYRFFC"
     gene            complement(<21138..>21839)
                     /gene="GTT2"
                     /locus_tag="YLL060C"
                     /db_xref="GeneID:850666"
     mRNA            complement(<21138..>21839)
                     /gene="GTT2"
                     /locus_tag="YLL060C"
                     /product="glutathione transferase GTT2"
                     /transcript_id="NM_001181880.1"
                     /db_xref="GI:296146485"
                     /db_xref="GeneID:850666"
     CDS             complement(21138..21839)
                     /gene="GTT2"
                     /locus_tag="YLL060C"
                     /EC_number="2.5.1.18"
                     /note="Glutathione S-transferase capable of
                     homodimerization; functional overlap with Gtt2p, Grx1p,
                     and Grx2p; protein abundance increases in response to DNA
                     replication stress"
                     /codon_start=1
                     /product="glutathione transferase GTT2"
                     /protein_id="NP_013040.1"
                     /db_xref="GI:6322968"
                     /db_xref="SGD:S000003983"
                     /db_xref="GeneID:850666"
                     /translation="MNGRGFLIYNGGEKMKQKMIIYDTPAGPYPARVRIALAEKNMLS
                     SVQFVRINLWKGEHKKPEFLAKNYSGTVPVLELDDGTLIAECTAITEYIDALDGTPTL
                     TGKTPLEKGVIHMMNKRAELELLDPVSVYFHHATPGLGPEVELYQNKEWGLRQRDKAL
                     HGMHYFDTVLRERPYVAGDSFSMADITVIAGLIFAAIVKLQVPEECEALRAWYKRMQQ
                     RPSVKKLLEIRSKSS"
     gene            <23569..>25296
                     /locus_tag="YLL058W"
                     /db_xref="GeneID:850668"
     mRNA            <23569..>25296
                     /locus_tag="YLL058W"
                     /product="cystathionine gamma-synthase"
                     /transcript_id="NM_001181878.1"
                     /db_xref="GI:296146486"
                     /db_xref="GeneID:850668"
     CDS             23569..25296
                     /locus_tag="YLL058W"
                     /EC_number="2.5.1.48"
                     /note="hypothetical protein with similarity to Str2p;
                     Str2p is a cystathionine gamma-synthase important in
                     sulfur metabolism; YLL058W is not an essential gene"
                     /codon_start=1
                     /product="cystathionine gamma-synthase"
                     /protein_id="NP_013042.1"
                     /db_xref="GI:6322970"
                     /db_xref="SGD:S000003981"
                     /db_xref="GeneID:850668"
                     /translation="MTEIEFGQPLPSNLDYAVSFGIPTWDSAIGYAEKVPEVIGKMAT
                     GYPRYFPQPPVQRLCAYFVKKFGRGSENCRPFPSVNLGLKCFEYVKSVSGPESKAHLE
                     VETVTIKNRGAKTSKEPAELVLTIAAVLASEEEFETVKEYWKLRGECVSSRLALSVNQ
                     LLDCANHGSEQVLRELEAGVFAAKKGEEKAKNLIKGRIVENRFRPFGLEKKTPNWEGL
                     NLNPNEDVYLVSSGMSAISTARNLLTFWEEKKNSGDSLNKTTSDQKKKPLLCDTVGIF
                     GFPFKDTQVIMTKFGKCKFFGFGNSRDVVELQKFLETSKQRILAVFVETPSNPLLNMP
                     DLKKLRSLADQYGFFIVIDDTIGGLNVDILPYADIVSTSLTKLFNGASNVMGGSVVLN
                     PKSSLYPYAREYFRSANFEDLLWCEDAIVLERNSRDFEDRTLRANANTGILLNDLLLP
                     EEGKICKKIYYPTVTSKETFENYESVRNERGGYGCLFSVAFFNEGDAKAFYDSLKVFK
                     GPSNGTNFTLACPYVHLAHHSELEEVSKFGADPNIIRVSVGLEDIQWLLKVFSSALDV
                     VKSRGSKHS"
     gene            complement(<25756..>26994)
                     /gene="JLP1"
                     /locus_tag="YLL057C"
                     /db_xref="GeneID:850669"
     mRNA            complement(<25756..>26994)
                     /gene="JLP1"
                     /locus_tag="YLL057C"
                     /product="Jlp1p"
                     /transcript_id="NM_001181877.1"
                     /db_xref="GI:296146487"
                     /db_xref="GeneID:850669"
     CDS             complement(25756..26994)
                     /gene="JLP1"
                     /locus_tag="YLL057C"
                     /EC_number="1.14.11.-"
                     /note="Fe(II)-dependent sulfonate/alpha-ketoglutarate
                     dioxygenase; involved in sulfonate catabolism for use as a
                     sulfur source; contains sequence that resembles a J domain
                     (typified by the E. coli DnaJ protein); induced by sulphur
                     starvation"
                     /codon_start=1
                     /product="Jlp1p"
                     /protein_id="NP_013043.1"
                     /db_xref="GI:6322971"
                     /db_xref="SGD:S000003980"
                     /db_xref="GeneID:850669"
                     /translation="MSPAAAQTAIPLPSTDLPVKIITNGLKNLNYTSKQGYGNFDTHF
                     YDGQDEVSPSGLLKIRKSYREKSKYPDYLPTWDPTEKYGPLEFHEYHDPALRADGNFS
                     NLFAKENVGQLKVKKITPKLGLEINGIQLTDLSDAAKDELALLVAQKGVVVFRNQNFA
                     DEGPDYVTEYGRHFGKLHIHQTSGHPQNNPELHITFRRPDAEEFARVFDDSTSSGGWH
                     TDVSYELQPPSYTFFSVVEGPDGGGDTLFADTIEAFDRLSKPLQDFLSTLHVIHSSKE
                     QAENSQRQGGIKRRAPVTHIHPLVRVHPVLKKKCLYVNRAFSRKIVELKRQESESLLN
                     FLYNLVESSHDLQLRAKWEPHSVVIWDNRRVQHSAVIDWEEPIHRHAFRITPQAERPV
                     EDLKFLNDENYYPSSLTLDI"
     gene            complement(<27409..>28305)
                     /locus_tag="YLL056C"
                     /db_xref="GeneID:850670"
     mRNA            complement(<27409..>28305)
                     /locus_tag="YLL056C"
                     /product="hypothetical protein"
                     /transcript_id="NM_001181876.1"
                     /db_xref="GI:296146488"
                     /db_xref="GeneID:850670"
     CDS             complement(27409..28305)
                     /locus_tag="YLL056C"
                     /note="hypothetical protein; transcription is activated by
                     paralogous transcription factors Yrm1p and Yrr1p and genes
                     involved in pleiotropic drug resistance (PDR); expression
                     is induced in cells treated with the mycotoxin patulin"
                     /codon_start=1
                     /product="hypothetical protein"
                     /protein_id="NP_013044.1"
                     /db_xref="GI:6322972"
                     /db_xref="SGD:S000003979"
                     /db_xref="GeneID:850670"
                     /translation="MKVFITGASGFIGSAVLSELISSGHEVVGLARSDEAAAKIKSID
                     PAAKILRGDLKDLEILKKGATESDGVIHLGFVHDFKNFEQCCEIDRQATVAMLESLKG
                     SNKPFLYTNGTLSLRPNKVANEQDGIDEDSKILRAVTEQVALSYKDKGVSARIVRLPF
                     SVHGKGDKAFVPILMNIAKAAGKSGYVGQGTNAWAAVHRLDTAPLFRLVLEKGKTGQV
                     YHCVGEQGIPFKDIARVIGEILNVPVASIPVDDAESHFGFLTCFVTRDGPVSSEGTRK
                     ELGWQPQQIGLLEDIRANYSLN"
     gene            <30109..>31704
                     /gene="YCT1"
                     /locus_tag="YLL055W"
                     /db_xref="GeneID:850671"
     mRNA            <30109..>31704
                     /gene="YCT1"
                     /locus_tag="YLL055W"
                     /product="Yct1p"
                     /transcript_id="NM_001181875.1"
                     /db_xref="GI:296146489"
                     /db_xref="GeneID:850671"
     CDS             30109..31704
                     /gene="YCT1"
                     /locus_tag="YLL055W"
                     /note="High-affinity cysteine-specific transporter; has
                     similarity to the Dal5p family of transporters; green
                     fluorescent protein (GFP)-fusion protein localizes to the
                     endoplasmic reticulum; YCT1 is not an essential gene"
                     /codon_start=1
                     /product="Yct1p"
                     /protein_id="NP_013045.1"
                     /db_xref="GI:6322973"
                     /db_xref="SGD:S000003978"
                     /db_xref="GeneID:850671"
                     /translation="MSKVDVKIGADSISSSDEILVPSRLADVTLAFMEENDAAVPEIT
                     PEQEKKLKRKLFLTIFTFVSAINLLLYMDKATLSYDSILGFFEDTGLTQNTYNTVNTL
                     FYVGFAIGQFPGQYLAQKLPLGKFLGGLLATWTILIFLSCTAYNFSGVVALRFFLGLT
                     ESVVIPILITTMGMFFDASERAAAQPFFFAACMGSPIPTGFIAYGVLHITNPSISLWK
                     IFTIIIGGLTFIMTVVVILWFPNNPADVKFFSIQERVWIIRRVQASTGSSIEQKVFKK
                     SQFREAMKDYITWLFGLFFLLQQLANNLPYQQNLLFEGMGGVDALGSTLVSVAGAGFA
                     VVCAFIATLMLAKWKNISALTAIFWTLPALVGSIAAAALPWDNKIGILANICMAGQIF
                     GIPFIIALSWASSSASGYTKKLTRSSVSLFAMGIANIISPQIWREKDSPRFLPAWIVQ
                     IVLSFSLAPAILLLIHFILKRRNNQRLKNYDENLQNYLDRIQLIESENPSSIEEGKVV
                     THENNLAVFDLTDLENETFIYPL"
     rep_origin      30209..31384
                     /gene="YCT1"
                     /locus_tag="YLL055W"
                     /note="ARS1202;
                     Putative replication origin; identified in multiple array
                     studies, not yet confirmed by plasmid-based assay"
                     /db_xref="SGD:S000130180"
     gene            complement(<32673..>35204)
                     /locus_tag="YLL054C"
                     /db_xref="GeneID:850672"
     mRNA            complement(<32673..>35204)
                     /locus_tag="YLL054C"
                     /product="hypothetical protein"
                     /transcript_id="NM_001181874.2"
                     /db_xref="GI:330443668"
                     /db_xref="GeneID:850672"
     CDS             complement(32673..35204)
                     /locus_tag="YLL054C"
                     /note="hypothetical protein with similarity to Pip2p; an
                     oleate-specific transcriptional activator of peroxisome
                     proliferation; YLL054C is not an essential gene"
                     /codon_start=1
                     /product="hypothetical protein"
                     /protein_id="NP_013046.2"
                     /db_xref="GI:330443669"
                     /db_xref="SGD:S000003977"
                     /db_xref="GeneID:850672"
                     /translation="MSIASQKKVKPSFVCLRCKQRKIKCDKLWPTCSKCKASSSICSY
                     EVEPGRINKSPTIENAPHRDIRNITPASMSASGSFTSILNPSTKDWEMKNFAMNLSNA
                     HDKLVVMNNTTIVDSPFAFHSILQHDLYAKALTTCIHERILIDVERHRENVSANNKKR
                     ELNLTIGDIGPLFFIDKAALKFIENTSKTSKLYPPIDFLYNTYDYEQAHPEENNDKIS
                     INILLEELSKYFLNKNEVDGLIVDFYKTIYPVYPLLEISLFEDNIRELLQLNEFNGYN
                     IVFAGKDSRRKLETITLLTIILAFSYRRLSLSTSHSFKESFGVKSNNLTLLAHKLLAL
                     MNVFQYVNEHTLCCLLYFFILRYLNPDQADMYPTHSDILNLKFLENVAIKLGLNEEPF
                     QYTRYVSESDDYPRLFNLRRKLWLGVQFLKFGILIPEGDSDILSLEYLRSFMKTDESL
                     PELFERNYASTNNLDLSLMATAENIYHLHLSLQVLLTSCFPINGPSYLKEVLDNIDKT
                     KDFLNQKFPLILSSLGEPRMKSLHINVPSSLANEESFDFSTFEENETFIANVISYTCT
                     MNIYDSLSLHFENQCFKNALEYKTYYHRFTFTAIQDYLTLLKLISEYFNGSLLHLREP
                     FGFATQKVVRFSIHRLLIFQATLLVRLFYKKDTCDRSSAAMGMLNDRNGRLSRVIEKM
                     IKLMSYHMKLLVEIVISKLEKSYLGSFISVSIFRYIIYLVDTDALSAFISDYWKSDAV
                     MDERYSRIHRIVGLKWGMGRDKSFSFTSKLNNPQFLGSLDLEILEELEKLISAQEFSR
                     NFTEDVDESLQSEIDLMNYDNEALNQLMAIDLDKLLGIFPNLSNF"
     gene            complement(<35503..>35961)
                     /locus_tag="YLL053C"
                     /db_xref="GeneID:850673"
     mRNA            complement(<35503..>35961)
                     /locus_tag="YLL053C"
                     /product="hypothetical protein"
                     /transcript_id="NM_001181873.1"
                     /db_xref="GI:296146491"
                     /db_xref="GeneID:850673"
     CDS             complement(35503..35961)
                     /locus_tag="YLL053C"
                     /note="Putative protein; in the Sigma 1278B strain
                     background YLL053C is contiguous with AQY2 which encodes
                     an aquaporin"
                     /codon_start=1
                     /product="hypothetical protein"
                     /protein_id="NP_013047.1"
                     /db_xref="GI:6322975"
                     /db_xref="SGD:S000003976"
                     /db_xref="GeneID:850673"
                     /translation="MWFPQIIAGMAAGGAASAMTPGKVLFTNALGLGCSRSRGLFLEM
                     FGTAVLCLTVLMTAVEKRETNFMAALPIGISLFMAHMALTGYTGTGVNPARSLGAAVA
                     ARYFPHYHWIYWISPLLGAFLAWSVWQLLQILDYTTYVNAEKAAGQKKED"
     gene            complement(<35912..>36361)
                     /gene="AQY2"
                     /locus_tag="YLL052C"
                     /db_xref="GeneID:850674"
     mRNA            complement(<35912..>36361)
                     /gene="AQY2"
                     /locus_tag="YLL052C"
                     /product="Aqy2p"
                     /transcript_id="NM_001181872.1"
                     /db_xref="GI:296146492"
                     /db_xref="GeneID:850674"
     CDS             complement(35912..36361)
                     /gene="AQY2"
                     /locus_tag="YLL052C"
                     /note="Water channel that mediates water transport across
                     cell membranes; only expressed in proliferating cells;
                     controlled by osmotic signals; may be involved in freeze
                     tolerance; disrupted by a stop codon in many S. cerevisiae
                     strains"
                     /codon_start=1
                     /product="Aqy2p"
                     /protein_id="NP_013048.1"
                     /db_xref="GI:6322976"
                     /db_xref="SGD:S000003975"
                     /db_xref="GeneID:850674"
                     /translation="MSNESNDLEKNISHLDPTGVDNAYIPPEQPETKHSRFNIDRDTL
                     RNHFIAAVGEFCGTFMFLWCAYVICNVANHDVALTTEPEGSHPGQLIMIALGFGFSVM
                     FSIWCFWWGFEPSRFSLFVFGQSHLTSQMCSDVVSSDHCWDGCWWCR"
     gene            complement(<37333..>39471)
                     /gene="FRE6"
                     /locus_tag="YLL051C"
                     /db_xref="GeneID:850675"
     mRNA            complement(<37333..>39471)
                     /gene="FRE6"
                     /locus_tag="YLL051C"
                     /product="Fre6p"
                     /transcript_id="NM_001181871.1"
                     /db_xref="GI:296146493"
                     /db_xref="GeneID:850675"
     CDS             complement(37333..39471)
                     /gene="FRE6"
                     /locus_tag="YLL051C"
                     /EC_number="1.16.1.9"
                     /note="Putative ferric reductase with similarity to Fre2p;
                     expression induced by low iron levels"
                     /codon_start=1
                     /product="Fre6p"
                     /protein_id="NP_013049.1"
                     /db_xref="GI:6322977"
                     /db_xref="SGD:S000003974"
                     /db_xref="GeneID:850675"
                     /translation="MHRTLLFLTWLISLTKAFNIKLPHTEKKDHLESNAVLACASYIN
                     TLKWSFDSSVVPGFYSTICSYSPAFDTWSLCIFNSLTDQIIPMDNTSFEESLGNVRKT
                     CSFVDKKFSNISLEQYYSSLNNASSHALEDYGSIESLSTSIRVDRETRSRWIRAFHAH
                     AYNLDISSVYGAYLTYYFVIVGIIAVFFHMSHYNGLNRALFASRFVNYIRGHFVLPTF
                     LVDKHANHFKFLNVEVFTGLMPNSLEAWIIFGYTLANIIFLSISYIIDPYNLIFNSHL
                     SQFTRLLADRSGILAFTQFPLIIIFTARNSFLEFLTGVKFNSFISFHKWIGRIMVLNA
                     TIHSLSYSLFAIINHAFKISNKQLYWKFGIASITVLCVLLVLSLGIVRKRHYEFFLYT
                     HIILALLFFYCCWQHVKIFNGWKEWIVVSLLIWGLEKLFRIWNILQFRFPKATLINLN
                     TSNNPHDEMFKVIIPKYNRRWHSKPGQYCFIYFLHPLVFWQCHPFTIIDEGEKCVLVI
                     KPKSGLTRFIYNHILQSLNGKLQLRVAIEGPYGPSNLHLDKFDHLLLLSGGTGLPGPL
                     DHAIKLSRNPDKPKSIDLIMAIKNPSFLNGYKSEILELKNSRSHVNVQVYLTQKTAVT
                     KAANARDQLIHFDDIMTELTSFAHIGNARPNFSNVIENAIKSTPPGDSLAVVCCGPPV
                     LVDDVRNTVSQKLLGYPERIIEYFEEYQCW"
     gene            complement(<39804..>40414)
                     /gene="COF1"
                     /locus_tag="YLL050C"
                     /db_xref="GeneID:850676"
     mRNA            complement(join(<39804..40221,40401..>40414))
                     /gene="COF1"
                     /locus_tag="YLL050C"
                     /product="cofilin"
                     /transcript_id="NM_001181870.1"
                     /db_xref="GI:296146494"
                     /db_xref="GeneID:850676"
     CDS             complement(join(39804..40221,40401..40414))
                     /gene="COF1"
                     /locus_tag="YLL050C"
                     /note="Cofilin, involved in pH-dependent actin filament
                     depolarization; binds both actin monomers and filaments
                     and severs filaments; involved in the selective sorting,
                     export of the secretory cargo from the late golgi;
                     genetically interacts with pmr1; thought to be regulated
                     by phosphorylation at SER4; ubiquitous and essential in
                     eukaryotes"
                     /codon_start=1
                     /product="cofilin"
                     /protein_id="NP_013050.1"
                     /db_xref="GI:6322978"
                     /db_xref="SGD:S000003973"
                     /db_xref="GeneID:850676"
                     /translation="MSRSGVAVADESLTAFNDLKLGKKYKFILFGLNDAKTEIVVKET
                     STDPSYDAFLEKLPENDCLYAIYDFEYEINGNEGKRSKIVFFTWSPDTAPVRSKMVYA
                     SSKDALRRALNGVSTDVQGTDFSEVSYDSVLERVSRGAGSH"
     gene            <40666..>41205
                     /gene="LDB18"
                     /locus_tag="YLL049W"
                     /db_xref="GeneID:850677"
     mRNA            <40666..>41205
                     /gene="LDB18"
                     /locus_tag="YLL049W"
                     /product="Ldb18p"
                     /transcript_id="NM_001181869.1"
                     /db_xref="GI:296146495"
                     /db_xref="GeneID:850677"
     CDS             40666..41205
                     /gene="LDB18"
                     /locus_tag="YLL049W"
                     /note="Component of the dynactin complex; dynactin is
                     required for dynein activity; null mutant exhibits defects
                     in nuclear migration and spindle orientation and has
                     reduced affinity for alcian blue dye; has homology to
                     mammalian dynactin subunit p24"
                     /codon_start=1
                     /product="Ldb18p"
                     /protein_id="NP_013051.1"
                     /db_xref="GI:6322979"
                     /db_xref="SGD:S000003972"
                     /db_xref="GeneID:850677"
                     /translation="MPGLKLVEALEYRCDRLERLIGAGYSANSDVSVQLDELYNQLHR
                     LYFQGLKYSQDLLQLFNTFMAEDIENVGAPDDICIFASCFDDIYTLYSAFDELNSQYM
                     EFCQISKSSLDQISFKDANIETKQLKKLPELVDNCNIMILRSIAILNRFIDWNIEVNG
                     FFQFQKKRLLNLQKVIYST"
     gene            complement(<41280..>46265)
                     /gene="YBT1"
                     /locus_tag="YLL048C"
                     /gene_synonym="BAT1"
                     /db_xref="GeneID:850678"
     mRNA            complement(<41280..>46265)
                     /gene="YBT1"
                     /locus_tag="YLL048C"
                     /gene_synonym="BAT1"
                     /product="bile acid-transporting ATPase YBT1"
                     /transcript_id="NM_001181868.1"
                     /db_xref="GI:296146496"
                     /db_xref="GeneID:850678"
     CDS             complement(41280..46265)
                     /gene="YBT1"
                     /locus_tag="YLL048C"
                     /gene_synonym="BAT1"
                     /note="Transporter of the ATP-binding cassette (ABC)
                     family; involved in bile acid transport; negative
                     regulator of vacuole fusion; regulates release of lumenal
                     Ca2+ stores; similar to mammalian bile transporters; YBT1
                     has a paralog, VMR1, that arose from the whole genome
                     duplication"
                     /codon_start=1
                     /product="bile acid-transporting ATPase YBT1"
                     /protein_id="NP_013052.1"
                     /db_xref="GI:6322980"
                     /db_xref="SGD:S000003971"
                     /db_xref="GeneID:850678"
                     /translation="MHHVLNSTRPDHRFWFYDDVTQYGRTKYLNYYTPLVLLIFTVLF
                     ITYNIWKHYYYYDVLHLKQKNPIDELLYSSTDEDEQSPLINNNTITTNYVDNNCTKDA
                     LKNRHFSLEKLKSVKVNGEPHGTPEIVRRGFIEKSRIILEFFLVLSQVIIHSFILLHY
                     VNKNPEFTQQGTITGLVEWCALFIIVSLRLANVNQNFKFINKYPGNLWSVSFINYLAL
                     FISMILPFRSIFIHHINSPISRKYYISQISINLALFLLLFFARIRNNFAIIYKTDSWI
                     TPSPEPVTSIAGFICWAWLDSFVWKAHKVSIKVKDIWGLMMQDYSFFVVKKFRYFVDH
                     KVKRKRIFSLNLFFFFSNYLVLQCFWAFLGSVLSFIPTVLLKRILEYVEDQSSAPSNL
                     AWFYVTVMFVGRILVAICQAQALFFGRRVCIRMKSIIISEIYTKALRRKISTNKTKPS
                     NEDPQEINDQKSINGDEESTSSANLGAIINLMAIDAFKVSEICGYLHSFLEAFVMTVV
                     ALALLYRLLGFAAIVGVLIIVAMLPLNYKLAKYIGDLQKKNLAVTDNRIQKLNEAFQA
                     IRIIKYFSWEENFEKDINTIRENELSLLLMRSIVWSISSFLWFVTPTIVTAASFAYYI
                     YVQGEVLTTPVAFTALSLFTLLRDPLDRLSDMLSFVVQSKVSLDRVQDFLNENDTKKY
                     DQLTIDPNGNRFAFENSTISWDKDNQDFKLKDLNIEFKTGKLNVVIGPTGSGKTSLLM
                     ALLGEMYLLNGKVVVPALEPRQELIVDANGTTNSIAYCSQAAWLLNDTVKNNILFNSP
                     FNEARYKAVVEACGLKRDFEILKAGDLTEIGEKGITLSGGQKQRVSLARALYSNARHV
                     LLDDCLSAVDSHTASWIYDNCITGPLMEDRTCILVSHNIALTLRNAELVVLLEDGRVK
                     DQGDPIDMLQKGLFGEDELVKSSILSRANSSANLAAKSSTSLSNLPAVKEQQVSVNNN
                     SSHFEAKKLQKSLRTEAERTEDGKLIKEETKEEGVVGLDVYKWYLKIFGGWKIVSFLA
                     SLFLIAQLLYIGQSWWVRAWASHNVIAKIIPRAQRAIAFISKKASHLIDWRGSSQISM
                     ASAENQPSSGHSTMYYLVLYLIIGFAQALLGAGKTILNFVAGINASRKIFNMILNKVL
                     HSKIRFFDATPTGRIMNRFSKDIEAIDQELTPYIQGAFYSLIECLSTVILITFITPQF
                     LSVAIVVSILYYFVGYFYMAGSRELKRFESISRSPIYQHFSETLVGVTTIRAFGDEGR
                     FMQENLHKIDENNKPFFYLWVANRWLAFRIDMIGSLVIFGAGLFILFNINNLDSGMAG
                     ISLTYAISFTEGALWLVRLYSEVEMNMNSVERVKEYMEIEQEPYNEHKEIPPPQWPQD
                     GKIEVNDLSLRYAPNLPRVIKNVSFSVDAQSKIGIVGRTGAGKSTIITALFRFLEPET
                     GHIKIDNIDISGVDLQRLRRSITIIPQDPTLFSGTIKTNLDPYDEFSDRQIFEALKRV
                     NLISEEQLQQGATRETSNEASSTNSENVNKFLDLSSEISEGGSNLSQGQRQLMCLARS
                     LLRSPKIILLDEATASIDYSSDAKIQETIRKEFQGSTILTIAHRLRSVIDYDKILVMD
                     AGEVKEYDHPYSLLLNKQSAFYSMCEHSGELDILIELAKKAFVEKLNSKKD"
     gene            complement(<46714..>47463)
                     /gene="RNP1"
                     /locus_tag="YLL046C"
                     /db_xref="GeneID:850680"
     mRNA            complement(<46714..>47463)
                     /gene="RNP1"
                     /locus_tag="YLL046C"
                     /product="Rnp1p"
                     /transcript_id="NM_001181866.1"
                     /db_xref="GI:296146497"
                     /db_xref="GeneID:850680"
     CDS             complement(46714..47463)
                     /gene="RNP1"
                     /locus_tag="YLL046C"
                     /note="Ribonucleoprotein that contains two RNA recognition
                     motifs (RRM); RNP1 has a paralog, SBP1, that arose from
                     the whole genome duplication"
                     /codon_start=1
                     /product="Rnp1p"
                     /protein_id="NP_013054.1"
                     /db_xref="GI:6322982"
                     /db_xref="SGD:S000003969"
                     /db_xref="GeneID:850680"
                     /translation="MLIEEIEFYNVNGKKTTTVVPENTKIKKRVLNDRRTLYVGNLPK
                     NCRKQDLRDLFEPNYGKITINMLKKKPLKKPLKRFAFIEFQEGVNLKKVKEKMNGKIF
                     MNEKIVIENILTKEEKSFEKNQKSNKKTAPDLKPLSTNTLYVKNIPMKSTNEDLAKIF
                     GVDPKNINFVRRELVDLRTNKVFFSDEFHTGEAFIKFDNLGTGDSIQKKCREFKGRKA
                     SNGRVLLVKIASAKKNEQKQEGGDNTKIKQN"
     gene            complement(<47859..>48629)
                     /gene="RPL8B"
                     /locus_tag="YLL045C"
                     /gene_synonym="KRB1; SCL41"
                     /db_xref="GeneID:850682"
     mRNA            complement(<47859..>48629)
                     /gene="RPL8B"
                     /locus_tag="YLL045C"
                     /gene_synonym="KRB1; SCL41"
                     /product="ribosomal 60S subunit protein L8B"
                     /transcript_id="NM_001181865.1"
                     /db_xref="GI:296146498"
                     /db_xref="GeneID:850682"
     CDS             complement(47859..48629)
                     /gene="RPL8B"
                     /locus_tag="YLL045C"
                     /gene_synonym="KRB1; SCL41"
                     /note="Ribosomal 60S subunit protein L8B; required for
                     processing of 27SA3 pre-rRNA to 27SB pre-rRNA during
                     assembly of large ribosomal subunit; depletion leads to a
                     turnover of pre-rRNA; L8 binds to Domain I of 25S and 5.8
                     S rRNAs; mutation results in decreased amounts of free 60S
                     subunits; homologous to mammalian ribosomal protein L7A,
                     no bacterial homolog; RPL8B has a paralog, RPL8A, that
                     arose from the whole genome duplication"
                     /codon_start=1
                     /product="ribosomal 60S subunit protein L8B"
                     /protein_id="NP_013055.1"
                     /db_xref="GI:6322984"
                     /db_xref="SGD:S000003968"
                     /db_xref="GeneID:850682"
                     /translation="MAPGKKVAPAPFGAKSTKSNKAKNPLTHSTPKNFGIGQAVQPKR
                     NLSRYVKWPEYVRLQRQKKILSIRLKVPPTIAQFQYTLDRNTAAETFKLFNKYRPETA
                     AEKKERLTKEAAAIAEGKSKQDASPKPYAVKYGLNHVVSLIENKKAKLVLIANDVDPI
                     ELVVFLPALCKKMGVPYAIIKGKARLGTLVNQKTSAVAALTEVRAEDEAALAKLVSTI
                     DANFADKYDEVKKHWGGGILGNKAQAKMDKRAKTSDSA"
     gene            <49938..>51947
                     /gene="FPS1"
                     /locus_tag="YLL043W"
                     /db_xref="GeneID:850683"
     mRNA            <49938..>51947
                     /gene="FPS1"
                     /locus_tag="YLL043W"
                     /product="Fps1p"
                     /transcript_id="NM_001181863.1"
                     /db_xref="GI:296146499"
                     /db_xref="GeneID:850683"
     CDS             49938..51947
                     /gene="FPS1"
                     /locus_tag="YLL043W"
                     /note="Aquaglyceroporin, plasma membrane channel; involved
                     in efflux of glycerol and xylitol, and in uptake of acetic
                     acid and the trivalent metalloids arsenite and antimonite;
                     role in mediating passive diffusion of glycerol is key
                     factor in maintenance of redox balance; member of major
                     intrinsic protein (MIP) family; phosphorylated by Hog1p
                     MAPK under acetate stress; deletion improves xylose
                     fermentation"
                     /codon_start=1
                     /product="Fps1p"
                     /protein_id="NP_013057.1"
                     /db_xref="GI:6322985"
                     /db_xref="SGD:S000003966"
                     /db_xref="GeneID:850683"
                     /translation="MSNPQKALNDFLSSESVHTHDSSRKQSNKQSSDEGRSSSQPSHH
                     HSGGTNNNNNNNNNNNNSNNNNNGNDGGNDDDYDYEMQDYRPSPQSARPTPTYVPQYS
                     VESGTAFPIQEVIPSAYINTQDINHKDNGPPSASSNRAFRPRGQTTVSANVLNIEDFY
                     KNADDAHTIPESHLSRRRSRSRATSNAGHSANTGATNGRTTGAQTNMESNESPRNVPI
                     MVKPKTLYQNPQTPTVLPSTYHPINKWSSVKNTYLKEFLAEFMGTMVMIIFGSAVVCQ
                     VNVAGKIQQDNFNVALDNLNVTGSSAETIDAMKSLTSLVSSVAGGTFDDVALGWAAAV
                     VMGYFCAGGSAISGAHLNPSITLANLVYRGFPLKKVPYYFAGQLIGAFTGALILFIWY
                     KRVLQEAYSDWWMNESVAGMFCVFPKPYLSSGRQFFSEFLCGAMLQAGTFALTDPYTC
                     LSSDVFPLMMFILIFIINASMAYQTGTAMNLARDLGPRLALYAVGFDHKMLWVHHHHF
                     FWVPMVGPFIGALMGGLVYDVCIYQGHESPVNWSLPVYKEMIMRAWFRRPGWKKRNRA
                     RRTSDLSDFSYNNDDDEEFGERMALQKTKTKSSISDNENEAGEKKVQFKSVQRGKRTF
                     GGIPTILEEEDSIETASLGATTTDSIGLSDTSSEDSHYGNAKKVT"
     gene            complement(<52087..>52590)
                     /gene="ATG10"
                     /locus_tag="YLL042C"
                     /gene_synonym="APG10"
                     /db_xref="GeneID:850684"
     mRNA            complement(<52087..>52590)
                     /gene="ATG10"
                     /locus_tag="YLL042C"
                     /gene_synonym="APG10"
                     /product="Atg10p"
                     /transcript_id="NM_001181862.1"
                     /db_xref="GI:296146500"
                     /db_xref="GeneID:850684"
     CDS             complement(52087..52590)
                     /gene="ATG10"
                     /locus_tag="YLL042C"
                     /gene_synonym="APG10"
                     /EC_number="6.3.2.-"
                     /note="Conserved E2-like conjugating enzyme; mediates
                     formation of the Atg12p-Atg5p conjugate, which is a
                     critical step in autophagy"
                     /codon_start=1
                     /product="Atg10p"
                     /protein_id="NP_013058.1"
                     /db_xref="GI:6322986"
                     /db_xref="SGD:S000003965"
                     /db_xref="GeneID:850684"
                     /translation="MIPYQEWHSQLQSLYDSQIFHNWALCQDVHLNDEKDGLLLRLIP
                     TRQLQKNTERIENKLLNHIELYLTYSKVYNEPLLLLRIWEEKSIDGIPMTKLMLPTDI
                     ESLLDVQGKFQLGLDTIINLEGSVWYSFHPCDTSCIVGDQAEFMSTYLRRWVSIFIFS
                     WLGYEDS"
     gene            complement(<53131..>53931)
                     /gene="SDH2"
                     /locus_tag="YLL041C"
                     /gene_synonym="ACN17"
                     /db_xref="GeneID:850685"
     mRNA            complement(<53131..>53931)
                     /gene="SDH2"
                     /locus_tag="YLL041C"
                     /gene_synonym="ACN17"
                     /product="succinate dehydrogenase iron-sulfur protein
                     subunit SDH2"
                     /transcript_id="NM_001181861.1"
                     /db_xref="GI:296146501"
                     /db_xref="GeneID:850685"
     CDS             complement(53131..53931)
                     /gene="SDH2"
                     /locus_tag="YLL041C"
                     /gene_synonym="ACN17"
                     /EC_number="1.3.5.1"
                     /note="Iron-sulfur protein subunit of succinate
                     dehydrogenase; the complex couples the oxidation of
                     succinate to the transfer of electrons to ubiquinone as
                     part of the TCA cycle and the mitochondrial respiratory
                     chain; other members are Sdh1p, Sdh3p, and Sdh4p"
                     /codon_start=1
                     /product="succinate dehydrogenase iron-sulfur protein
                     subunit SDH2"
                     /protein_id="NP_013059.1"
                     /db_xref="GI:6322987"
                     /db_xref="SGD:S000003964"
                     /db_xref="GeneID:850685"
                     /translation="MLNVLLRRKAFCLVTKKGMATATTAAATHTPRLKTFKVYRWNPD
                     EPSAKPHLQSYQVDLNDCGPMVLDALLKIKDEQDSTLTFRRSCREGICGSCAMNIGGR
                     NTLACICKIDQNESKQLKIYPLPHMFIVKDLVPDLTNFYQQYKSIQPYLQRSSFPKDG
                     TEVLQSIEDRKKLDGLYECILCACCSTSCPSYWWNQEQYLGPAVLMQAYRWLIDSRDQ
                     ATKTRKAMLNNSMSLYRCHTIMNCTRTCPKGLNPGLAIAEIKKSLAFA"
     gene            complement(<54211..>63645)
                     /gene="VPS13"
                     /locus_tag="YLL040C"
                     /gene_synonym="SOI1; VPT2"
                     /db_xref="GeneID:850619"
     mRNA            complement(<54211..>63645)
                     /gene="VPS13"
                     /locus_tag="YLL040C"
                     /gene_synonym="SOI1; VPT2"
                     /product="Vps13p"
                     /transcript_id="NM_001181860.1"
                     /db_xref="GI:296146502"
                     /db_xref="GeneID:850619"
     CDS             complement(54211..63645)
                     /gene="VPS13"
                     /locus_tag="YLL040C"
                     /gene_synonym="SOI1; VPT2"
                     /note="Protein involved in prospore membrane
                     morphogenesis; heterooligomeric or homooligomeric complex;
                     peripherally associated with membranes; involved in
                     sporulation, vacuolar protein sorting, prospore membrane
                     formation during sporulatoin, and protein-Golgi retention;
                     homologous to human CHAC and COH1 which are involved in
                     chorea acanthocytosis and Cohen syndrome, respectively"
                     /codon_start=1
                     /product="Vps13p"
                     /protein_id="NP_013060.1"
                     /db_xref="GI:6322988"
                     /db_xref="SGD:S000003963"
                     /db_xref="GeneID:850619"
                     /translation="MLESLAANLLNRLLGSYVENFDPNQLNVGIWSGDVKLKNLKLRK
                     DCLDSLNLPIDVKSGILGDLVLTVPWSSLKNKPVKIIIEDCYLLCSPRSEDHENDEEM
                     IKRAFRLKMRKVSEWELTNQARILSTQSENKTSSSSSEKNNAGFMQSLTTKIIDNLQV
                     TIKNIHLRYEDMDGIFTTGPSSVGLTLNELSAVSTDSNWAPSFIDITQNITHKLLTLN
                     SLCLYWNTDSPPLISDDDQDRSLENFVRGFKDMIASKNSTAPKHQYILKPVSGLGKLS
                     INKLGSTEEQPHIDLQMFYDEFGLELDDTEYNDILHVLSSIQLRQITKKFKKARPSFA
                     VSENPTEWFKYIAACVINEIHEKNKMWTWESMKEKCEQRRLYTKLWVEKLKLKNLEAP
                     LRDPIQEAQLSELHKDLTYDEIILFRSVAKRQYAQYKLGMTEDSPTPTASSNIEPQTS
                     NKSATKNNGSWLSSWWNGKPTEEVDEDLIMTEEQRQELYDAIEFDENEDKGPVLQVPR
                     ERVELRVTSLLKKGSFTIRKKKQNLNLGSIIFENCKVDFAQRPDSFLSSFQLNKFSLE
                     DGSPNALYKHIISVRNSSKDQSSIDNHATGEEEEEDEPLLRASFELNPLDGLADSNLN
                     IKLLGMTVFYHVHFITEVHKFFKASNQHMETIGNIVNAAEATVEGWTTQTRMGIESLL
                     EDHKTVNVSLDLQAPLIILPLDPHDWDTPCAIIDAGHMSILSDLVPKEKIKEIKELSP
                     EEYDKIDGNEINRLMFDRFQILSQDTQIFVGPDIQSTIGKINTASSTNDFRILDKMKL
                     ELTVDLSILPKAYKLPTIRVFGHLPRLSLSINDIQYKTIMNLIANSIPSMIDDEENNG
                     DYVNYSSGSEKEMKKQIQLQLKNTLKALENMQPLQIEQKFLELHFDIDQAKIAFFQCI
                     KNDSRNSEKLVDILCQRLNFNFDKRAKEMNLDLRVHSLDVEDYIELTDNKEFKNLISS
                     GVEKVTRSQKDLFTLKYKRVQRIVPHNDTLIELFDQDIVMHMSELQLVLTPRSVLTLM
                     NYAMLTFTDPNAPEMPADVLRHNKEDRDDAPQKINMKIKMEAVNVIFNDDSIKLATLV
                     LSAGEFTMVLLPERYNINLKLGGLELTDETNESFSRDSVFRKIIQMKGQELVELSYES
                     FDPATNTKDYDSFLKYSTGSMHVNFIESAVNRMVNFFAKFQKSKVSFDRARLAAYNQA
                     PSIDAVNNMKMDIVIKAPIIQFPKLVGTQENNYDTMRFYLGEFFIENKFSVIDESHKI
                     NHIKLGVREGQLSSNLNFDGSSQQLYLVENIGLLFNIDRDPLPQDDTPELKVTSNFES
                     FALDLTENQLTYLLEISNKVSSAFNITDENSGESGGKGEIKSPSPDPASLSSESERTA
                     TPQSLQGSNKSNIKNPEQKYLDFSFKAPKIALTLYNKTKGVTSLNDCGLTRIMFQDIG
                     CSLGLKNDGTVDGQAHVAAFRIEDVRNIKDNKHTELIPKSKNKEYQFVANISRKNLEV
                     GRLLNISMTMDSPKMILAMDYLVSLKEFFDAIMSKSHENNLYYPENTNQKPENKAIVE
                     SVQEGGDVTKIQYSVNIIETALILLADPCDMNSEAISFKIGQFLVTDQNIMTVAANNV
                     GIFLFKMNSSEEKLRLLDDFSSSLTIDKRNSTPQTLMTNIQLSVQPLLMRISLRDIRL
                     AMLIFKRVTTLLNKMTEKEDNGEEEESTDKIQFSHEFERKLAVLDPSILGERSRASQS
                     SDSESIEVPTAILKNETFNADLGGLRFILIGDVHEMPILDMNVNEITASAKDWSTDFE
                     ALASLETYVNIFNYSRSSWEPLLEMIPITFHLSKGHSEMDPAFSFDILTQRIAEITLS
                     ARSIAMLSHIPASLTEELPLASRVSQKPYQLVNDTELDFDVWIQDKTTEDNKNEVVLL
                     KANTSLPWEFEDWRSIREKLDIDKSKNILGVCVSGQNYKTIMNIDATTEGENLHVLSP
                     PRNNVHNRIVCEARCDENNVKIITFRSTLVIENTTSTEIELLVDSKDPNKPSLKYAIK
                     PHQSKSVPVEYAYDSDIRIRPASEDIYDWSQQTLSWKSLLSNQMSIFCSSKEDSNQRF
                     HFEIGAKYDEREPLAKIFPHMKIVVSASMTIENLLPADINFSIFDKREEKRTDFLKTG
                     ESMEVHHISLDSFLLMSVQPLQDEASASKPSIVNTPHKSPLNPEDSLSLTLSGGQNLL
                     LKLDYKNIDGTRSKVIRIYSPYIIMNSTDRELYIQSSLLNIAQSKILLENEKRYTIPK
                     MFSFDKEDDKSNRARIRFKESEWSSKLSFDAIGQSFDASVRIKNKEQESNLGINISEG
                     KGKYLLSKVIEIAPRYIISNTLDIPIEVCETGSMDVQQIESNITKPLYRMRNIVDKQL
                     VLKFLGGDSNWSQPFFIKNVGVTYLKVLKNSRHKLLKIEILLDKATIFIRIKDGGDRW
                     PFSIRNFSDHDFIFYQRDPRKVSDPYKDDQSNESSSRSFKPIFYRIPSKSIMPYAWDF
                     PTAKEKYLVLESGTRTREVRLAEIGELPPLRLDKRSKDKPAPIVGLHVVADDDMQALV
                     IVNYKANVGLYKLKTASATTTSSVSVNSSVTDGFVQKDEDEKVNTQIVVSFKGVGISL
                     INGRLQELLYINMRGIELRYNESKAYQTFSWKMKWMQIDNQLFSGNYSNILYPTEIPY
                     TEKEIENHPVISGSISKVNDSLQAVPYFKHVTLLIQEFSIQLDEDMLYAMMDFIKFPG
                     SPWIMDSRDYKYDEEIQLPDVSELKTAGDIYFEIFHIQPTVLHLSFIRSDEISPGLAE
                     ETEESFSSSLYYVHMFAMTLGNINEAPVKVNSLFMDNVRVPLPILMDHIERHYTTQFV
                     YQIHKILGSADCFGNPVGLFNTISSGVWDLFYEPYQGYMMNDRPQEIGIHLAKGGLSF
                     AKKTVFGLSDSMSKFTGSMAKGLSVTQDLEFQRVRRLQQRINKNNRNALANSAQSFAS
                     TLGSGLSGIALDPYKAMQKEGAAGFLKGLGKGIVGLPTKTAIGFLDLTSNLSQGVKST
                     TTVLDMQKGCRVRLPRYVDHDQIIKPYDLREAQGQYWLKTVNGGVFMNDEYLSHVILP
                     GKELAVIVSMQHIAEVQMATQELMWSTGYPSIQGITLERSGLQIKLKSQSEYFIPISD
                     PEERRSLYRNIAIAVREYNKYCEAIL"
     gene            complement(<64062..>65207)
                     /gene="UBI4"
                     /locus_tag="YLL039C"
                     /gene_synonym="SCD2; UB14"
                     /db_xref="GeneID:850620"
     mRNA            complement(<64062..>65207)
                     /gene="UBI4"
                     /locus_tag="YLL039C"
                     /gene_synonym="SCD2; UB14"
                     /product="ubiquitin"
                     /transcript_id="NM_001181859.1"
                     /db_xref="GI:296146503"
                     /db_xref="GeneID:850620"
     CDS             complement(64062..65207)
                     /gene="UBI4"
                     /locus_tag="YLL039C"
                     /gene_synonym="SCD2; UB14"
                     /note="Ubiquitin; becomes conjugated to proteins, marking
                     them for selective degradation via the ubiquitin-26S
                     proteasome system; essential for the cellular stress
                     response; encoded as a polyubiquitin precursor comprised
                     of 5 head-to-tail repeats; protein abundance increases in
                     response to DNA replication stress"
                     /codon_start=1
                     /product="ubiquitin"
                     /protein_id="NP_013061.1"
                     /db_xref="GI:6322989"
                     /db_xref="SGD:S000003962"
                     /db_xref="GeneID:850620"
                     /translation="MQIFVKTLTGKTITLEVESSDTIDNVKSKIQDKEGIPPDQQRLI
                     FAGKQLEDGRTLSDYNIQKESTLHLVLRLRGGMQIFVKTLTGKTITLEVESSDTIDNV
                     KSKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGGMQIFVKTL
                     TGKTITLEVESSDTIDNVKSKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKEST
                     LHLVLRLRGGMQIFVKTLTGKTITLEVESSDTIDNVKSKIQDKEGIPPDQQRLIFAGK
                     QLEDGRTLSDYNIQKESTLHLVLRLRGGMQIFVKTLTGKTITLEVESSDTIDNVKSKI
                     QDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGGN"
     gene            complement(<65775..>66518)
                     /gene="ENT4"
                     /locus_tag="YLL038C"
                     /db_xref="GeneID:850621"
     mRNA            complement(<65775..>66518)
                     /gene="ENT4"
                     /locus_tag="YLL038C"
                     /product="Ent4p"
                     /transcript_id="NM_001181858.1"
                     /db_xref="GI:296146504"
                     /db_xref="GeneID:850621"
     CDS             complement(65775..66518)
                     /gene="ENT4"
                     /locus_tag="YLL038C"
                     /note="hypothetical protein; contains an N-terminal
                     epsin-like domain; proposed to be involved in the
                     trafficking of Arn1p in the absence of ferrichrome"
                     /codon_start=1
                     /product="Ent4p"
                     /protein_id="NP_013062.1"
                     /db_xref="GI:6322990"
                     /db_xref="SGD:S000003961"
                     /db_xref="GeneID:850621"
                     /translation="MPLLDTFKSFIQSPTESKVKQATNEDETSGATGTLMNEISILTY
                     SPKTVREIIQVIRKRLLLGQNRRNSHRNCIQVMKTLTLVSYLMNNGSNEFIKWLKGNM
                     ILIEILEDFQVQDPRDERKAEDIQKLSRNVLGLLQDDGLLEKQRKDVIQFRSSISTPG
                     RKSTDNSHLKLEEMRSELTRQSLEKKAKPPTTSTSLDFQRQRTRNTHEYARFSLDPLA
                     EEDSEDTPGVAGGISKLSFRPKSSNNPFR"
     gene            complement(<66745..>68256)
                     /gene="PRP19"
                     /locus_tag="YLL036C"
                     /gene_synonym="PSO4"
                     /db_xref="GeneID:850623"
     mRNA            complement(<66745..>68256)
                     /gene="PRP19"
                     /locus_tag="YLL036C"
                     /gene_synonym="PSO4"
                     /product="E3 ubiquitin-protein ligase PRP19"
                     /transcript_id="NM_001181856.1"
                     /db_xref="GI:296146505"
                     /db_xref="GeneID:850623"
     CDS             complement(66745..68256)
                     /gene="PRP19"
                     /locus_tag="YLL036C"
                     /gene_synonym="PSO4"
                     /note="Splicing factor associated with the spliceosome;
                     contains a U-box, a motif found in a class of ubiquitin
                     ligases, and a WD40 domain; relocalizes to the cytosol in
                     response to hypoxia"
                     /codon_start=1
                     /product="E3 ubiquitin-protein ligase PRP19"
                     /protein_id="NP_013064.1"
                     /db_xref="GI:6322992"
                     /db_xref="SGD:S000003959"
                     /db_xref="GeneID:850623"
                     /translation="MLCAISGKVPRRPVLSPKSRTIFEKSLLEQYVKDTGNDPITNEP
                     LSIEEIVEIVPSAQQASLTESTNSATLKANYSIPNLLTSLQNEWDAIMLENFKLRSTL
                     DSLTKKLSTVMYERDAAKLVAAQLLMEKNEDSKDLPKSSQQAVAITREEFLQGLLQSS
                     RDFVARGKLKAPKWPILKNLELLQAQNYSRNIKTFPYKELNKSMYYDKWVCMCRCEDG
                     ALHFTQLKDSKTITTITTPNPRTGGEHPAIISRGPCNRLLLLYPGNQITILDSKTNKV
                     LREIEVDSANEIIYMYGHNEVNTEYFIWADNRGTIGFQSYEDDSQYIVHSAKSDVEYS
                     SGVLHKDSLLLALYSPDGILDVYNLSSPDQASSRFPVDEEAKIKEVKFADNGYWMVVE
                     CDQTVVCFDLRKDVGTLAYPTYTIPEFKTGTVTYDIDDSGKNMIAYSNESNSLTIYKF
                     DKKTKNWTKDEESALCLQSDTADFTDMDVVCGDGGIAAILKTNDSFNIVALTP"
     gene            <68580..>70478
                     /gene="GRC3"
                     /locus_tag="YLL035W"
                     /db_xref="GeneID:850624"
     mRNA            <68580..>70478
                     /gene="GRC3"
                     /locus_tag="YLL035W"
                     /product="Grc3p"
                     /transcript_id="NM_001181855.1"
                     /db_xref="GI:296146506"
                     /db_xref="GeneID:850624"
     CDS             68580..70478
                     /gene="GRC3"
                     /locus_tag="YLL035W"
                     /EC_number="2.7.1.-"
                     /note="Polynucleotide kinase present on rDNA; required for
                     efficient transcription termination by RNA polymerase I;
                     functions with Las1p in a conserved mechanism to modulate
                     rRNA processing and ribosome biogenesis; required for cell
                     growth; mRNA is cell-cycle regulated"
                     /codon_start=1
                     /product="Grc3p"
                     /protein_id="NP_013065.1"
                     /db_xref="GI:6322993"
                     /db_xref="SGD:S000003958"
                     /db_xref="GeneID:850624"
                     /translation="MVIDSKQDLPQYTKDSGSESDSDSSNNFIVESPSIPSSKSATVV
                     LNSEEYEDDEGDDLNGLDAELIDNITYEGDEDETMFVGLKEKQKLHLSGVFRLQVVKG
                     GIVYNNVHYNASREILTFWHPLSQSIPTIDFSHFAGWQDTFFMPRNNRFKIRDEEFKS
                     FPCVLRVFNSNHTGLLEAGHLYRDVNYLWKPKEPYFPLNERTTYHLLHESDRIQSLSV
                     PGYWSTPLEKLYLSHKNAAYDTRIMVIGGKNSGKSTFLRLLLEKFTQDIRDSTTSQEE
                     LVYLDLDPGQPEYSLPDSISLNKILSSPISLGQHLCQGSNFQTLLQFYAGSSSPQDEP
                     TSYLNCADKLIDHLEEQAFFGTSLLNLPGWIKGFGMQILNHIIRKYKPTHLLFLETAN
                     SKRHLDELTIPQSFSTSLRDAYAPEVVRVPAHSLNHTLSSRFHASQLRTFKILALFHK
                     ITQFDYDFAPLLKSAPLQISYGKGKSGIKGIQFPMEFQDLNPQDIKSALEGTVIGIYT
                     YSGEDSLEVKSLNTFPILQSCTSSSKNFITLGLIHSIDTSQQIMNIYVPPCHTQILDK
                     QPEDAQWIIVRNKTETPFCDFLPSPRTITWDDNIQIPFATFERRKKLEHVWKVRKNVM
                     RRGQFMKR"
     gene            complement(<70633..>73146)
                     /gene="RIX7"
                     /locus_tag="YLL034C"
                     /db_xref="GeneID:850625"
     mRNA            complement(<70633..>73146)
                     /gene="RIX7"
                     /locus_tag="YLL034C"
                     /product="putative AAA family ATPase RIX7"
                     /transcript_id="NM_001181854.1"
                     /db_xref="GI:296146507"
                     /db_xref="GeneID:850625"
     CDS             complement(70633..73146)
                     /gene="RIX7"
                     /locus_tag="YLL034C"
                     /note="Putative ATPase of the AAA family; required for
                     export of pre-ribosomal large subunits from the nucleus;
                     distributed between the nucleolus, nucleoplasm, and
                     nuclear periphery depending on growth conditions"
                     /codon_start=1
                     /product="putative AAA family ATPase RIX7"
                     /protein_id="NP_013066.1"
                     /db_xref="GI:6322994"
                     /db_xref="SGD:S000003957"
                     /db_xref="GeneID:850625"
                     /translation="MVKVKSKKNSLTSSLDNKIVDLIYRLLEEKTLDRKRSLRQESQG
                     EEGENNEGEEDEDIFESMFFAKDLTAGEIFTFCLTKDLSLQRVKKVVLQKTIDRMLKD
                     VIESELEEFGSYPGYNNEEEEKPSLEEELAKKNMMIERDTNEMNKRITSTWSKSGSVS
                     ESITETDDPKTEEVKKSKKRSKEGTCKVKRQKIKEDRSPPNSSLKSLGGMDDVVAQLM
                     ELIGLPILHPEIFLSTGVEPPRGVLLHGPPGCGKTSIANALAGELQVPFISISAPSVV
                     SGMSGESEKKIRDLFDEARSLAPCLVFFDEIDAITPKRDGGAQREMERRIVAQLLTSM
                     DELTMEKTNGKPVIIIGATNRPDSLDAALRRAGRFDREICLNVPNEVSRLHILKKMSD
                     NLKIDGAIDFAKLAKLTPGFVGADLKALVTAAGTCAIKRIFQTYANIKSTPTTATDSS
                     EDNMEIDETANGDESSLKNTANMIDPLPLSVVQQFIRNYPEPLSGEQLSLLSIKYEDF
                     LKALPTIQPTAKREGFATVPDVTWANVGALQRVRLELNMAIVQPIKRPELYEKVGISA
                     PGGVLLWGPPGCGKTLLAKAVANESRANFISIKGPELLNKYVGESERSIRQVFTRARA
                     SVPCVIFFDELDALVPRRDTSLSESSSRVVNTLLTELDGLNDRRGIFVIGATNRPDMI
                     DPAMLRPGRLDKSLFIELPNTEEKLDIIKTLTKSHGTPLSSDVDFEEIIRNEKCNNFS
                     GADLAALVRESSVLALKRKFFQSEEIQSVLDNDLDKEFEDLSVGVSGEEIIVTMSDFR
                     SALRKIKPSVSDKDRLKYDRLNKKMGLTEEMKDAEEMKQ"
     gene            <73409..>74101
                     /gene="IRC19"
                     /locus_tag="YLL033W"
                     /gene_synonym="RRG4"
                     /db_xref="GeneID:850626"
     mRNA            <73409..>74101
                     /gene="IRC19"
                     /locus_tag="YLL033W"
                     /gene_synonym="RRG4"
                     /product="Irc19p"
                     /transcript_id="NM_001181853.1"
                     /db_xref="GI:296146508"
                     /db_xref="GeneID:850626"
     CDS             73409..74101
                     /gene="IRC19"
                     /locus_tag="YLL033W"
                     /gene_synonym="RRG4"
                     /note="hypothetical protein; YLL033W is not an essential
                     gene but mutant is defective in spore formation; null
                     mutant displays increased levels of spontaneous Rad52p
                     foci"
                     /codon_start=1
                     /product="Irc19p"
                     /protein_id="NP_013067.1"
                     /db_xref="GI:6322995"
                     /db_xref="SGD:S000003956"
                     /db_xref="GeneID:850626"
                     /translation="MRKPSITITTAKAIITPDYTLIKSHSKYQLPSRFQKLDADSPER
                     STVVKLFYRRFMRLKPFISNVKMVKDTYRDYVRYKFMKENYELKRYLVFNPDGLRSKI
                     NLELLSNTKCCERILPVTEMQRTLEFVLKSCSYLPETKVQKWDIARDNTYCRQILKNL
                     LTMQYEKYRSILHRGIGHDELDVKFSHLKTTSSPLTKLNKTEKKKIPLFKVFSDFDTT
                     LIYLNETLGTRL"
     gene            complement(<74270..>76747)
                     /locus_tag="YLL032C"
                     /db_xref="GeneID:850627"
     mRNA            complement(<74270..>76747)
                     /locus_tag="YLL032C"
                     /product="hypothetical protein"
                     /transcript_id="NM_001181852.1"
                     /db_xref="GI:296146509"
                     /db_xref="GeneID:850627"
     CDS             complement(74270..76747)
                     /locus_tag="YLL032C"
                     /note="hypothetical protein; may interact with ribosomes,
                     based on co-purification experiments; green fluorescent
                     protein (GFP)-fusion protein localizes to the cytoplasm;
                     YLL032C is not an essential gene"
                     /codon_start=1
                     /product="hypothetical protein"
                     /protein_id="NP_013068.1"
                     /db_xref="GI:6322996"
                     /db_xref="SGD:S000003955"
                     /db_xref="GeneID:850627"
                     /translation="MDNFKIYSTVITTAFLQVPHLYTTNRLWKPIEAPFLVEFLQKRI
                     SSKELKNTKAICHIDPSWVNLNASFIRDDMISIKATTDDMDLDAICRISLPLPMNTND
                     LTAELEKMKRILLDLSEKFNLELIITKEPAYFTPEQTGESKELCIYVHALGFRSNLME
                     CEPQLLAFVDLIKKNGMTLPPQHYIIEPMELNSYSVLPLYMGVDMENFKHISRAFKTS
                     IYAPSLITLSRDLKANPQIFFSGAVHSLSLLARKTLRESISVNSKSFFYRRLTNITPG
                     KLLFIRKYYQQKVNQLILKYQSLIRVTNEYIEFQSISTNLLEMVIKNFTIQVLHEIVE
                     VQISLNENCAMSPELIIDSFFGHTGNQIVVITPKEDSFNQLIVVGNQSSTDEASDTSI
                     LHYLSDFIMGSNQVINPNLRQIKAIFEIHPDFEDFISGKKNGKLTRIMELSACLIQLE
                     MEEEDDNLYLNLVSDSFPDFKESFKNVINEFPAEESFFIPEVCHRPIIGTGGSLIQAT
                     MRKHNVFIQFSNSFNLPQNKISMIRYDNVIIRCPRKNKANICLAKNDLKQIVQEYDSL
                     QSKTLIRFSSGQYRHILHVNGQKNIIGQIEKNENVYIMIPLKEPLDGTSQLSIQGNDE
                     NASRAANELVNSAFGYEYEFKIDQEIDPNKEYEFYNLIVVPFLQIMNIIVTFEKDLIT
                     FTFEKDTNENTLTKAIELLSNYLETQKTKIIFKKIIKKFVLGSASSKSNTSNSNTNGN
                     FRSMNNAKSRTTIDNTSQSGASPQRHKMPVITTVGGAQAIKGYIPNTYYNGYGYGYGY
                     TYEYDYNYANSNKAQTNNRHKYQNGRK"
     gene            complement(<77152..>80205)
                     /gene="GPI13"
                     /locus_tag="YLL031C"
                     /gene_synonym="MPC1"
                     /db_xref="GeneID:850628"
     mRNA            complement(<77152..>80205)
                     /gene="GPI13"
                     /locus_tag="YLL031C"
                     /gene_synonym="MPC1"
                     /product="Gpi13p"
                     /transcript_id="NM_001181851.1"
                     /db_xref="GI:296146510"
                     /db_xref="GeneID:850628"
     CDS             complement(77152..80205)
                     /gene="GPI13"
                     /locus_tag="YLL031C"
                     /gene_synonym="MPC1"
                     /EC_number="2.-.-.-"
                     /note="ER membrane localized phosphoryltransferase; adds
                     phosphoethanolamine onto the third mannose residue of the
                     glycosylphosphatidylinositol (GPI) anchor precursor;
                     similar to human PIG-O protein"
                     /codon_start=1
                     /product="Gpi13p"
                     /protein_id="NP_013069.1"
                     /db_xref="GI:6322997"
                     /db_xref="SGD:S000003954"
                     /db_xref="GeneID:850628"
                     /translation="MDEKTIKKSILSSSNDEKIIYKSRIKKFQKNHKFYIILLVFIAI
                     LQFISIAFFTRGFLLSRHVLDNISSQNETSKLPPRFNKAVILVIDALRFDFAIPVNES
                     HSNYNLNYHNNILSLYDSFASDKDASSLLLKFIADPPTTTLQRLKGLTTGSLPTFIDA
                     GSNFDGTVIEEDNFLKQLHLANKTVKFAGDDTWMALFHPFLSNDSFPLESLNVWDLDT
                     VDNGVMDYFHDHLQQDKEWDVMIGHMLGIDHVGHKYGPDHFTMREKQIQVDQFIDWIL
                     KSIDDDTLLVILGDHGMDHTGNHGGDSIDELESTLFLYSKKPDMWRLKETSNYNIDNL
                     GHDYRSVRQIDLVSSLALLMGQPIPFNNLGWPIDEIARNDREWSQFVNSAISQLQLYK
                     DTMQIHHGNDEILEPLAKNISNTPPTSDPEKFVKLGHKYQKVFLQTCEELWAKFDYYS
                     IATGITLLATSLVLLISITKLIPSIVVNQMVPEFVPGIIIMVLVTNLCFHGIFYVYQQ
                     PSFVDQFWGTLLATAIGIIIGCYITIFDRYNFIWIAMRLGETLADYWSRIAVMFMIIH
                     ALLFTSNSFTIWEDRIVAFLLSTFGMLTLYEFVFLPKRQSTTALLTATISEKEGTTSG
                     VNPSTANSNYLPLTRFARLLGGYHSAVLIIFTRLASMITICREEQGEYCIPTFNNQNN
                     SSWWVLGLCFLMIFILPACITGYYNLTSSYQAAAPIWINVFLKGILGLNFVYWSLTSL
                     ENNSAVIAIPFLRDVTIFKFTLARIIAGFSLIASNVGWLMGPLCIKLNIHNTDVKSHE
                     ATILGYTNIYGSEFFLLVINVLISILLFNKPLAQLSYFLMCNQLLSILEIIDLLKLKE
                     NIIGPIALGLLSYQHFFTTGHQATIPSVQWDIGFMLSEKVTFPFTQIAIILNTFGPHI
                     LVSLSVALLTLWSQPPDVLKPQTLLGRIVSNCGILLTYNTILCLSSFIWVTHFRRHLM
                     VWKIFCPRFIFASLSLIVTQLVVTFGTIAFASGRLIKHINDIFWK"
     gene            <81461..>83710
                     /gene="FRA1"
                     /locus_tag="YLL029W"
                     /db_xref="GeneID:850630"
     mRNA            <81461..>83710
                     /gene="FRA1"
                     /locus_tag="YLL029W"
                     /product="Fra1p"
                     /transcript_id="NM_001181849.1"
                     /db_xref="GI:296146511"
                     /db_xref="GeneID:850630"
     CDS             81461..83710
                     /gene="FRA1"
                     /locus_tag="YLL029W"
                     /EC_number="3.4.11.9"
                     /note="Protein involved in negative regulation of iron
                     regulon transcription; forms an iron independent complex
                     with Fra2p, Grx3p, and Grx4p; cytosolic; mutant fails to
                     repress transcription of iron regulon and is defective in
                     spore formation"
                     /codon_start=1
                     /product="Fra1p"
                     /protein_id="NP_013071.1"
                     /db_xref="GI:6322999"
                     /db_xref="SGD:S000003952"
                     /db_xref="GeneID:850630"
                     /translation="MTSKPSTSDGRAHSISHVPGTHMRGTSASHSPRPFRPCADCTCS
                     PGLLSRQGRRASLFLRQLENSRRSSSMLLNELKGAGGGSSAGNGSVYSCDSLCAVNRE
                     VNTTDRLLKLRQEMKKHDLCCYIVPSCDEHQSEYVSLRDQRRAFISGFSGSAGVACIT
                     RDLLNFNDDHPDGKSILSTDGRYFNQARQELDYNWTLLRQNEDPITWQEWCVREALEM
                     AKGLGNKEGMVLKIGIDPKLITFNDYVSFRKMIDTKYDAKGKVELVPVEENLVDSIWP
                     DFETLPERPCNDLLLLKYEFHGEEFKDKKEKLLKKLNDKASSATTGRNTFIVVALDEI
                     CWLLNLRGSDIDYNPVFFSYVAINEDETILFTNNPFNDDISEYFKINGIEVRPYEQIW
                     EHLTKITSQASSAEHEFLIPDSASWQMVRCLNTSTNANGAIAKKMTAQNFAIIHSPID
                     VLKSIKNDIEIKNAHKAQVKDAVCLVQYFAWLEQQLVGREALIDEYRAAEKLTEIRKT
                     QRNFMGNSFETISSTGSNAAIIHYSPPVENSSMIDPTKIYLCDSGSQFLEGTTDITRT
                     IHLTKPTKEEMDNYTLVLKGGLALERLIFPENTPGFNIDAIARQFLWSRGLDYKHGTG
                     HGIGSFLNVHEGPMGVGFRPHLMNFPLRAGNIISNEPGYYKDGEYGIRIESDMLIKKA
                     TEKGNFLKFENMTVVPYCRKLINTKLLNEEEKTQINEYHARVWRTIVHFLQPQSISYK
                     WLKRETSPL"
     gene            <84804..>86564
                     /gene="TPO1"
                     /locus_tag="YLL028W"
                     /db_xref="GeneID:850631"
     mRNA            <84804..>86564
                     /gene="TPO1"
                     /locus_tag="YLL028W"
                     /product="Tpo1p"
                     /transcript_id="NM_001181848.1"
                     /db_xref="GI:296146512"
                     /db_xref="GeneID:850631"
     CDS             84804..86564
                     /gene="TPO1"
                     /locus_tag="YLL028W"
                     /note="Polyamine transporter of the major facilitator
                     superfamily; member of the 12-spanner drug:H(+) antiporter
                     DHA1 family; recognizes spermine, putrescine, and
                     spermidine; catalyzes uptake of polyamines at alkaline pH
                     and excretion at acidic pH; during oxidative stress
                     exports spermine, spermidine from the cell, which controls
                     timing of expression of stress-responsive genes;
                     phosphorylation enhances activity and sorting to the
                     plasma membrane"
                     /codon_start=1
                     /product="Tpo1p"
                     /protein_id="NP_013072.1"
                     /db_xref="GI:6323000"
                     /db_xref="SGD:S000003951"
                     /db_xref="GeneID:850631"
                     /translation="MSDHSPISNKENHLLPSDSSRSSSSDMHSTGTTGTTGVEPVDFT
                     GEGAKYTTATEGNGGADLAIQRTTTMNSAAESEVNITRRLTKILTGSVNEPDRVEVDY
                     TNCAPMGGDRPYPPSLPSRDLYEVTFDGPNDPLHPFNWPMKKKVLLCLVLCLDSIAIA
                     MCSSIFASAVPQICEIYHVIEVVAILGITLFVLGFAASPVIYAPLSELYGRKGVLVLS
                     AFGFALFQFAVATAENLQTIFICRFFGGFIGAAPMAVVPAAFADMFDTNVRGKAIALF
                     SLGVFVGPILSPVMGSYIAQRTTWRWLEYVVGCFASAVFVAIVLFFEETHHPTILVNK
                     AKQMRKQSNNWGIHAAHEDVELSIKDIVQKTVTRPIIMLFVEPLLLFVTIYNSFVYGI
                     LYLLLEAYPLVFVEGYGFTENGELPYIALIIGMMVCAAFIWYMDNDYLKRCRAKGKLV
                     PEARLYAMVIAGTVFPIGILWFCWTGYYPHKIHWMVPTVGGAFIGFGLMGIFLPCLNY
                     IIESYLLLAASAVAANTFMRSAFGACFPLFAGYMFRGMGIGWAGLLLGLFAAAMIPVP
                     LLFLKYGESIRKKSKYAYAA"
     gene            <87403..>88155
                     /gene="ISA1"
                     /locus_tag="YLL027W"
                     /db_xref="GeneID:850632"
     mRNA            <87403..>88155
                     /gene="ISA1"
                     /locus_tag="YLL027W"
                     /product="Isa1p"
                     /transcript_id="NM_001181847.1"
                     /db_xref="GI:296146513"
                     /db_xref="GeneID:850632"
     CDS             87403..88155
                     /gene="ISA1"
                     /locus_tag="YLL027W"
                     /note="Protein required for maturation of mitochondrial
                     [4Fe-4S] proteins; functions in a complex with Isa2p and
                     possibly Iba57p; isa1 deletion causes loss of
                     mitochondrial DNA and respiratory deficiency; depletion
                     reduces growth on nonfermentable carbon sources;
                     functional ortholog of bacterial A-type ISC proteins"
                     /codon_start=1
                     /product="Isa1p"
                     /protein_id="NP_013073.1"
                     /db_xref="GI:6323001"
                     /db_xref="SGD:S000003950"
                     /db_xref="GeneID:850632"
                     /translation="MINTGRSRNSVLLAHRFLSTGGFWRGGTNGTMSRTINNVNPFKL
                     KFIPKTVPAAADSVSPDSQRPGKKPFKFIVSNQSKSSKASKSPKWSSYAFPSRETIKS
                     HEEAIKKQNKAIDEQIAAAVSKNDCSCTEPPKKRKRKLRPRKALITLSPKAIKHLRAL
                     LAQPEPKLIRVSARNRGCSGLTYDLQYITEPGKFDEVVEQDGVKIVIDSKALFSIIGS
                     EMDWIDDKLASKFVFKNPNSKGTCGCGESFMV"
     gene            <88623..>91349
                     /gene="HSP104"
                     /locus_tag="YLL026W"
                     /db_xref="GeneID:850633"
     mRNA            <88623..>91349
                     /gene="HSP104"
                     /locus_tag="YLL026W"
                     /product="chaperone ATPase HSP104"
                     /transcript_id="NM_001181846.1"
                     /db_xref="GI:296146514"
                     /db_xref="GeneID:850633"
     CDS             88623..91349
                     /gene="HSP104"
                     /locus_tag="YLL026W"
                     /note="Disaggregase; heat shock protein that cooperates
                     with Ydj1p (Hsp40) and Ssa1p (Hsp70) to refold and
                     reactivate previously denatured, aggregated proteins;
                     responsive to stresses including: heat, ethanol, and
                     sodium arsenite; involved in [PSI+] propagation; protein
                     becomes more abundant and forms cytoplasmic foci in
                     response to DNA replication stress; potentiated Hsp104p
                     variants decrease TDP-43 proteotoxicity by eliminating its
                     cytoplasmic aggregation"
                     /codon_start=1
                     /product="chaperone ATPase HSP104"
                     /protein_id="NP_013074.1"
                     /db_xref="GI:6323002"
                     /db_xref="SGD:S000003949"
                     /db_xref="GeneID:850633"
                     /translation="MNDQTQFTERALTILTLAQKLASDHQHPQLQPIHILAAFIETPE
                     DGSVPYLQNLIEKGRYDYDLFKKVVNRNLVRIPQQQPAPAEITPSYALGKVLQDAAKI
                     QKQQKDSFIAQDHILFALFNDSSIQQIFKEAQVDIEAIKQQALELRGNTRIDSRGADT
                     NTPLEYLSKYAIDMTEQARQGKLDPVIGREEEIRSTIRVLARRIKSNPCLIGEPGIGK
                     TAIIEGVAQRIIDDDVPTILQGAKLFSLDLAALTAGAKYKGDFEERFKGVLKEIEESK
                     TLIVLFIDEIHMLMGNGKDDAANILKPALSRGQLKVIGATTNNEYRSIVEKDGAFERR
                     FQKIEVAEPSVRQTVAILRGLQPKYEIHHGVRILDSALVTAAQLAKRYLPYRRLPDSA
                     LDLVDISCAGVAVARDSKPEELDSKERQLQLIQVEIKALERDEDADSTTKDRLKLARQ
                     KEASLQEELEPLRQRYNEEKHGHEELTQAKKKLDELENKALDAERRYDTATAADLRYF
                     AIPDIKKQIEKLEDQVAEEERRAGANSMIQNVVDSDTISETAARLTGIPVKKLSESEN
                     EKLIHMERDLSSEVVGQMDAIKAVSNAVRLSRSGLANPRQPASFLFLGLSGSGKTELA
                     KKVAGFLFNDEDMMIRVDCSELSEKYAVSKLLGTTAGYVGYDEGGFLTNQLQYKPYSV
                     LLFDEVEKAHPDVLTVMLQMLDDGRITSGQGKTIDCSNCIVIMTSNLGAEFINSQQGS
                     KIQESTKNLVMGAVRQHFRPEFLNRISSIVIFNKLSRKAIHKIVDIRLKEIEERFEQN
                     DKHYKLNLTQEAKDFLAKYGYSDDMGARPLNRLIQNEILNKLALRILKNEIKDKETVN
                     VVLKKGKSRDENVPEEAEECLEVLPNHEATIGADTLGDDDNEDSMEIDDDLD"
     rep_origin      91419..91660
                     /note="ARS1206;
                     Autonomously Replicating Sequence"
                     /db_xref="SGD:S000118469"
     LTR             complement(92050..92381)
                     /note="Ty1 LTR"
                     /db_xref="SGD:S000007064"
     gene            92548..92650
                     /locus_tag="tP(UGG)L"
                     /db_xref="GeneID:850634"
     tRNA            join(92548..92583,92615..92650)
                     /locus_tag="tP(UGG)L"
                     /product="tRNA-Pro"
                     /note="Proline tRNA (tRNA-Pro), predicted by tRNAscan-SE
                     analysis; target of K. lactis zymocin"
                     /db_xref="SGD:S000006683"
                     /db_xref="GeneID:850634"
     gene            <94747..>95121
                     /gene="PAU17"
                     /locus_tag="YLL025W"
                     /db_xref="GeneID:850635"
     mRNA            <94747..>95121
                     /gene="PAU17"
                     /locus_tag="YLL025W"
                     /product="Pau17p"
                     /transcript_id="NM_001181845.1"
                     /db_xref="GI:296146515"
                     /db_xref="GeneID:850635"
     CDS             94747..95121
                     /gene="PAU17"
                     /locus_tag="YLL025W"
                     /note="hypothetical protein; member of the seripauperin
                     multigene family encoded mainly in subtelomeric regions;
                     YLL025W is not an essential gene"
                     /codon_start=1
                     /product="Pau17p"
                     /protein_id="NP_013075.1"
                     /db_xref="GI:6323003"
                     /db_xref="SGD:S000003948"
                     /db_xref="GeneID:850635"
                     /translation="MVKLTSIAAGVAAIAAGVAAAPATTTLSPSDERVNLVELGVYVS
                     DIRAHLAEYYMFQAAHPTETYPVEIAEAVFNYGDFTTMLTGIPADQVTRVITGVPWYS
                     TRLRPAISSALSADGIYTAVPN"
     gene            complement(<95566..>97485)
                     /gene="SSA2"
                     /locus_tag="YLL024C"
                     /gene_synonym="YG102"
                     /db_xref="GeneID:850636"
     mRNA            complement(<95566..>97485)
                     /gene="SSA2"
                     /locus_tag="YLL024C"
                     /gene_synonym="YG102"
                     /product="Hsp70 family chaperone SSA2"
                     /transcript_id="NM_001181844.1"
                     /db_xref="GI:296146516"
                     /db_xref="GeneID:850636"
     CDS             complement(95566..97485)
                     /gene="SSA2"
                     /locus_tag="YLL024C"
                     /gene_synonym="YG102"
                     /note="ATP-binding protein; involved in protein folding
                     and vacuolar import of proteins; member of heat shock
                     protein 70 (HSP70) family; associated with the
                     chaperonin-containing T-complex; present in the cytoplasm,
                     vacuolar membrane and cell wall; 98% identical with
                     paralog Ssa1p, but subtle differences between the two
                     proteins provide functional specificity with respect to
                     propagation of yeast [URE3] prions and vacuolar-mediated
                     degradations of gluconeogenesis enzymes"
                     /codon_start=1
                     /product="Hsp70 family chaperone SSA2"
                     /protein_id="NP_013076.1"
                     /db_xref="GI:6323004"
                     /db_xref="SGD:S000003947"
                     /db_xref="GeneID:850636"
                     /translation="MSKAVGIDLGTTYSCVAHFSNDRVDIIANDQGNRTTPSFVGFTD
                     TERLIGDAAKNQAAMNPANTVFDAKRLIGRNFNDPEVQGDMKHFPFKLIDVDGKPQIQ
                     VEFKGETKNFTPEQISSMVLGKMKETAESYLGAKVNDAVVTVPAYFNDSQRQATKDAG
                     TIAGLNVLRIINEPTAAAIAYGLDKKGKEEHVLIFDLGGGTFDVSLLSIEDGIFEVKA
                     TAGDTHLGGEDFDNRLVNHFIQEFKRKNKKDLSTNQRALRRLRTACERAKRTLSSSAQ
                     TSVEIDSLFEGIDFYTSITRARFEELCADLFRSTLDPVEKVLRDAKLDKSQVDEIVLV
                     GGSTRIPKVQKLVTDYFNGKEPNRSINPDEAVAYGAAVQAAILTGDESSKTQDLLLLD
                     VAPLSLGIETAGGVMTKLIPRNSTIPTKKSEVFSTYADNQPGVLIQVFEGERAKTKDN
                     NLLGKFELSGIPPAPRGVPQIEVTFDVDSNGILNVSAVEKGTGKSNKITITNDKGRLS
                     KEDIEKMVAEAEKFKEEDEKESQRIASKNQLESIAYSLKNTISEAGDKLEQADKDAVT
                     KKAEETIAWLDSNTTATKEEFDDQLKELQEVANPIMSKLYQAGGAPEGAAPGGFPGGA
                     PPAPEAEGPTVEEVD"
     gene            complement(<97997..>98836)
                     /gene="POM33"
                     /locus_tag="YLL023C"
                     /db_xref="GeneID:850637"
     mRNA            complement(<97997..>98836)
                     /gene="POM33"
                     /locus_tag="YLL023C"
                     /product="Pom33p"
                     /transcript_id="NM_001181843.1"
                     /db_xref="GI:296146517"
                     /db_xref="GeneID:850637"
     CDS             complement(97997..98836)
                     /gene="POM33"
                     /locus_tag="YLL023C"
                     /note="Transmembrane nucleoporin; involved in nuclear pore
                     complex (NPC) distribution, assembly or stabilization;
                     highly conserved across species, orthologous to human
                     TMEM33 and paralogous to Per33p; protein abundance
                     increases in response to DNA replication stress"
                     /codon_start=1
                     /product="Pom33p"
                     /protein_id="NP_013077.1"
                     /db_xref="GI:6323005"
                     /db_xref="SGD:S000003946"
                     /db_xref="GeneID:850637"
                     /translation="MSSRPANNQGPPNLPARDKSLVQRFMAVAKSLQFAWFTGHSVVL
                     ISSILYLLKMSEFYYRSAYLGVIESFGIIIYQQFFTRNEPLQTQDAAATKASIKSRVA
                     GLLKSEDVLYLVLANFWLFTPRFSFSLIPFFAFAVFHVLIYVEKVLLPKVFHLSSKDS
                     SKILSFIDKFVVQYNDLCMHWVGTAELLIFILVLFRAILCFQRSWIILVVYAIFIKLR
                     YENSKYMKAAFAQWRVRMDGIISHPSIPPFVKRAYNAIKMSLIRLSEYRLSGAPQVTK
                     KQN"
     gene            complement(<99044..>100201)
                     /gene="HIF1"
                     /locus_tag="YLL022C"
                     /db_xref="GeneID:850638"
     mRNA            complement(<99044..>100201)
                     /gene="HIF1"
                     /locus_tag="YLL022C"
                     /product="Hif1p"
                     /transcript_id="NM_001181842.1"
                     /db_xref="GI:296146518"
                     /db_xref="GeneID:850638"
     CDS             complement(99044..100201)
                     /gene="HIF1"
                     /locus_tag="YLL022C"
                     /note="Non-essential component of the HAT-B histone
                     acetyltransferase complex; localized to the nucleus; has a
                     role in telomeric silencing; other members are Hat1p and
                     Hat2p"
                     /codon_start=1
                     /product="Hif1p"
                     /protein_id="NP_013078.1"
                     /db_xref="GI:6323006"
                     /db_xref="SGD:S000003945"
                     /db_xref="GeneID:850638"
                     /translation="MKLRAEDVLANGTSRHKVQIDMERQVQIAKDLLAQKKFLEAAKR
                     CQQTLDSLPKDGLLPDPELFTIFAQAVYNMEVQNSGNLFGDALLAGDDGSGSESESEP
                     ESDVSNGEEGNENGQTEIPNSRMFQFDQEEEDLTGDVDSGDSEDSGEGSEEEEENVEK
                     EEERLALHELANFSPANEHDDEIEDVSQLRKSGFHIYFENDLYENALDLLAQALMLLG
                     RPTADGQSLTENSRLRIGDVYILMGDIEREAEMFSRAIHHYLKALGYYKTLKPAEQVT
                     EKVIQAEFLVCDALRWVDQVPAKDKLKRFKHAKALLEKHMTTRPKDSELQQARLAQIQ
                     DDIDEVQENQQHGSKRPLSQPTTSIGFPALEKPLGDFNDLSQLVKKKPRRH"
     gene            <100947..>105347
                     /gene="SPA2"
                     /locus_tag="YLL021W"
                     /gene_synonym="FUS6; PEA1; PPF1"
                     /db_xref="GeneID:850639"
     mRNA            <100947..>105347
                     /gene="SPA2"
                     /locus_tag="YLL021W"
                     /gene_synonym="FUS6; PEA1; PPF1"
                     /product="Spa2p"
                     /transcript_id="NM_001181841.1"
                     /db_xref="GI:296146519"
                     /db_xref="GeneID:850639"
     CDS             100947..105347
                     /gene="SPA2"
                     /locus_tag="YLL021W"
                     /gene_synonym="FUS6; PEA1; PPF1"
                     /note="Component of the polarisome; functions in actin
                     cytoskeletal organization during polarized growth; acts as
                     a scaffold for Mkk1p and Mpk1p cell wall integrity
                     signaling components; potential Cdc28p substrate; coding
                     sequence contains length polymorphisms in different
                     strains; SPA2 has a paralog, SPH1, that arose from the
                     whole genome duplication"
                     /codon_start=1
                     /product="Spa2p"
                     /protein_id="NP_013079.1"
                     /db_xref="GI:6323007"
                     /db_xref="SGD:S000003944"
                     /db_xref="GeneID:850639"
                     /translation="MGTSSEVSLAHHRDIFHYYVSLKTFFEVTGENRDRSNSTRAQKA
                     RAKLLKLSSSQFYELSTDVSDELQRRIGEDANQPDYLLPKANFHMKRNQARQKLANLS
                     QTRFNDLLDDILFEIKRRGFDKDLDAPRPPLPQPMKQEVSKDSDDTARTSTNSSSVTQ
                     VAPNVSVQPSLVIPKMASIDWSSEEEEEEQVKEKPNEPEGKQTSMDEKKEAKPALNPI
                     VTDSDLPDSQVLARDITSMARTPTTTHKNYWDVNDSPIIKVDKDIDNEKGPEQLKSPE
                     VQRAENNNPNSEMEDKVKELTDLNSDLHLQIEDLNAKLASLTSEKEKEKKEEKEEKEK
                     EKNLKINYTIDESFQKELLSLNSQIGELSIENENLKQKISEFELHQKKNDNHNDLKIT
                     DGFISKYSSADGLIPAQYILNANNLIIQFTTRLSAVPIGDSTAISHQIGEELFQILSQ
                     LSNLISQLLLSADLLQYKDQVILLKASLSHAITSIRYFSVYGPVLIPKITVQAAVSEV
                     CFAMCNLIDSAKIKSDSNGESTTSNEGNRQVLEYSSPTATTPMTPTFPSTSGINMKKG
                     FINPRKPASFLNDVEEEESPVKPLKITQKAINSPIIRPSSSNGVPTTSRKPSGTGLFS
                     LMIDSSIAKNSSHKEDNDKYVSPIKAVTSASNSASSNISEIPKLTLPPQAKIGTVIPP
                     SENQVPNIKIENTEEDNKRSDITNEISVKPTSSIADKLKQFEQSSEKKSSPKENPIAK
                     EEMDSKPKLSNKFITSMNDVSTDDSSSDGNENDDADDDDDFTYMALKQTMKREGSKIE
                     KNNDSKLPANIVELDLHESPESVKIESPESIKEITSSEMSSEMPSSSLPKRLVEDVEP
                     SEMPEKGASVESVRKKNFQEPLGNVESPDMTQKVKSLGMTGKAVGPESDSRVESPGMT
                     GQIKSLNMAGKVVGPEADSRVESPGMKEQIKSLGMTGKITAQESIKSPEAARKLASSG
                     EVDKIESPRMVRESESLEAVGNTIPSNMTVKMESPNLKGNTVSEPQEIRRDIASSEPI
                     ENVDPPKVLKKIVFPKAVNRTGSPKSVEKTPSSATLKKSGLPEPNSQIVSPELAKNSP
                     LAPIKKNVELRETNKPHTETITSVEPTNKDANTSWRDADLNRTIKREEEDEDFDRVNH
                     NIQITGAYTKTGKIDYHKIPVDRKAKSEAEVHTSEEDIDESNNVNGKRADAQIHITER
                     KHAFVNPTENSQVKKTSHSPFLNSKPVQYENSESNGGINNHIKIKNTGETTAHDEKHY
                     SDDDDSSYQFVPMKHEEQEQEQNRSEEEESEDDDEEEEDSDFDVDTFDIENPDNTLSE
                     LLLYLEHQTMDVISTIQSLLTSIKKPQVTKGNLRGESNAINQVIGQMVDATSISMEQS
                     RNANLKKHGDWVVQSLRDCSRRMTILCQLTGDGILAKEKSDQDYADKNFKQRLAGIAF
                     DVAKCTKELVKTVEEASLKDEINYLNSKLK"
     gene            complement(<105686..>107899)
                     /gene="KNS1"
                     /locus_tag="YLL019C"
                     /db_xref="GeneID:850641"
     mRNA            complement(<105686..>107899)
                     /gene="KNS1"
                     /locus_tag="YLL019C"
                     /product="Kns1p"
                     /transcript_id="NM_001181839.1"
                     /db_xref="GI:296146520"
                     /db_xref="GeneID:850641"
     CDS             complement(105686..107899)
                     /gene="KNS1"
                     /locus_tag="YLL019C"
                     /EC_number="2.7.12.1"
                     /note="Protein kinase involved in negative regulation of
                     PolIII transcription; effector kinase of the TOR signaling
                     pathway and phosphorylates Rpc53p to regulate ribosome and
                     tRNA biosynthesis; member of the LAMMER family of protein
                     kinases, which are serine/threonine kinases also capable
                     of phosphorylating tyrosine residues; capable of
                     autophosphorylation"
                     /codon_start=1
                     /product="Kns1p"
                     /protein_id="NP_013081.1"
                     /db_xref="GI:6323009"
                     /db_xref="SGD:S000003942"
                     /db_xref="GeneID:850641"
                     /translation="MSQNIQIGTRKRSRANMNNSTTTGPANNTSSNKTFLDNFEETRT
                     NKLLDEMFARQNSFLTDNLRNSLDLNQADNPLRPRQHQHQLFLDNENAIELDEEPRII
                     NTTINNSNNHNSSRVDEDADDDIIFIKEQPIQFSSPLILPSSSSINNNNNIVTSNNPG
                     CGTAATSNSTYITTPKKFKKQRTISLPQLPLSKLSYQSNYFNVPDQTNAIVPRVTQTE
                     NELLHLTGSCAKTLEGNKAVNLTIAHSTSPFSNPPAQIASLPQSNLKKQIGSSLRKFT
                     SNGSSESASSNKSNFKTDKDGHYVYQENDIFGSGGRFVVKDLLGQGTFGKVLKCIDNK
                     YEPNYVAVKVIRAVDRYREAAKTELRILQTILNNDPQGQFQCLLLRECFDYKNHICLV
                     TDLYGRSIYDFMCSNGIARFPGSHIQAIARQLIRSVCFLHDLGIIHTDLKPENILICD
                     ETHIAQKLPLKTVQSLSKRRREASKGKRKILKNPEIKIIDFGSAIFHYEYHPPVISTR
                     HYRAPEIVLGLGWSFPCDIWSIACVLVELVIGESLYPIHENLEHMAMMQRINGTPFPT
                     DIIDKMFYKSKHKLGNSPSDLNSTVIKHFDRKTLSLQWPEKNKRGDTITTEKSMKRVL
                     QSCDRLDIYISKVLKQDYGDSLSINWNLPPEKNWSLINSKLAWKRQTHSSSSSTTDEL
                     DKETFLFWYWFIDLLRKMFEFDPTKRITAKDALDHEWFNLGILDDGIATYNNTQG"
     gene            complement(<108676..>108972)
                     /gene="COX19"
                     /locus_tag="YLL018C-A"
                     /db_xref="GeneID:850642"
     mRNA            complement(<108676..>108972)
                     /gene="COX19"
                     /locus_tag="YLL018C-A"
                     /product="Cox19p"
                     /transcript_id="NM_001184338.1"
                     /db_xref="GI:296146521"
                     /db_xref="GeneID:850642"
     CDS             complement(108676..108972)
                     /gene="COX19"
                     /locus_tag="YLL018C-A"
                     /note="Protein required for cytochrome c oxidase assembly;
                     located in the cytosol and mitochondrial intermembrane
                     space; putative copper metallochaperone that delivers
                     copper to cytochrome c oxidase; contains twin
                     cysteine-x9-cysteine motifs"
                     /codon_start=1
                     /product="Cox19p"
                     /protein_id="NP_013082.1"
                     /db_xref="GI:6323010"
                     /db_xref="SGD:S000007245"
                     /db_xref="GeneID:850642"
                     /translation="MSGNPGSSLSALRPTPPERGSFPLDHDGECTKYMQEYLKCMQLV
                     QNENAMNCRLLAKDYLRCRMDHQLMDYDEWSHLGLPEDAPGNNGKTIKDATDNK"
     gene            complement(<109902..>111575)
                     /gene="DPS1"
                     /locus_tag="YLL018C"
                     /db_xref="GeneID:850643"
     mRNA            complement(<109902..>111575)
                     /gene="DPS1"
                     /locus_tag="YLL018C"
                     /product="aspartate--tRNA ligase DPS1"
                     /transcript_id="NM_001181838.1"
                     /db_xref="GI:296146522"
                     /db_xref="GeneID:850643"
     CDS             complement(109902..111575)
                     /gene="DPS1"
                     /locus_tag="YLL018C"
                     /EC_number="6.1.1.12"
                     /note="Aspartyl-tRNA synthetase, primarily cytoplasmic;
                     homodimeric enzyme that catalyzes the specific
                     aspartylation of tRNA(Asp); class II aminoacyl tRNA
                     synthetase; binding to its own mRNA may confer
                     autoregulation; shares five highly conserved amino acids
                     with human that when mutated cause leukoencephalopathy
                     characterized by hypomyelination with brain stem and
                     spinal cord involvement and leg spasticity (HBSL)"
                     /codon_start=1
                     /product="aspartate--tRNA ligase DPS1"
                     /protein_id="NP_013083.1"
                     /db_xref="GI:6323011"
                     /db_xref="SGD:S000003941"
                     /db_xref="GeneID:850643"
                     /translation="MSQDENIVKAVEESAEPAQVILGEDGKPLSKKALKKLQKEQEKQ
                     RKKEERALQLEAEREAREKKAAAEDTAKDNYGKLPLIQSRDSDRTGQKRVKFVDLDEA
                     KDSDKEVLFRARVHNTRQQGATLAFLTLRQQASLIQGLVKANKEGTISKNMVKWAGSL
                     NLESIVLVRGIVKKVDEPIKSATVQNLEIHITKIYTISETPEALPILLEDASRSEAEA
                     EAAGLPVVNLDTRLDYRVIDLRTVTNQAIFRIQAGVCELFREYLATKKFTEVHTPKLL
                     GAPSEGGSSVFEVTYFKGKAYLAQSPQFNKQQLIVADFERVYEIGPVFRAENSNTHRH
                     MTEFTGLDMEMAFEEHYHEVLDTLSELFVFIFSELPKRFAHEIELVRKQYPVEEFKLP
                     KDGKMVRLTYKEGIEMLRAAGKEIGDFEDLSTENEKFLGKLVRDKYDTDFYILDKFPL
                     EIRPFYTMPDPANPKYSNSYDFFMRGEEILSGAQRIHDHALLQERMKAHGLSPEDPGL
                     KDYCDGFSYGCPPHAGGGIGLERVVMFYLDLKNIRRASLFPRDPKRLRP"
     gene            112234..112545
                     /locus_tag="YLL017W"
                     /gene_synonym="SDC25"
                     /note="Non-essential Ras guanine nucleotide exchange
                     factor (GEF); localized to the membrane; expressed in poor
                     nutrient conditions and on nonfermentable carbon sources;
                     contains a stop codon in S288C, full-length gene includes
                     YLL016W; SDC25 has a paralog, CDC25, that arose from the
                     whole genome duplication"
                     /pseudo
                     /db_xref="GeneID:2827706"
                     /db_xref="SGD:S000003940"
     gene            112847..115993
                     /gene="SDC25"
                     /locus_tag="YLL016W"
                     /note="Non-essential Ras guanine nucleotide exchange
                     factor (GEF); localized to the membrane; expressed in poor
                     nutrient conditions and on nonfermentable carbon sources;
                     contains a stop codon in S288C, full-length gene includes
                     YLL017W; SDC25 has a paralog, CDC25, that arose from the
                     whole genome duplication"
                     /pseudo
                     /db_xref="GeneID:850644"
                     /db_xref="SGD:S000003939"
     gene            <116432..>121111
                     /gene="BPT1"
                     /locus_tag="YLL015W"
                     /db_xref="GeneID:850645"
     mRNA            <116432..>121111
                     /gene="BPT1"
                     /locus_tag="YLL015W"
                     /product="ATP-binding cassette bilirubin transporter BPT1"
                     /transcript_id="NM_001181835.1"
                     /db_xref="GI:296146523"
                     /db_xref="GeneID:850645"
     CDS             116432..121111
                     /gene="BPT1"
                     /locus_tag="YLL015W"
                     /note="ABC type transmembrane transporter of MRP/CFTR
                     family; found in vacuolar membrane, involved in the
                     transport of unconjugated bilirubin and in heavy metal
                     detoxification via glutathione conjugates, along with
                     Ycf1p"
                     /codon_start=1
                     /product="ATP-binding cassette bilirubin transporter BPT1"
                     /protein_id="NP_013086.1"
                     /db_xref="GI:6323014"
                     /db_xref="SGD:S000003938"
                     /db_xref="GeneID:850645"
                     /translation="MSSLEVVDGCPYGYRPYPDSGTNALNPCFISVISAWQAVFFLLI
                     GSYQLWKLYKNNKVPPRFKNFPTLPSKINSRHLTHLTNVCFQSTLIICELALVSQSSD
                     RVYPFILKKALYLNLLFNLGISLPTQYLAYFKSTFSMGNQLFYYMFQILLQLFLILQR
                     YYHGSSNERLTVISGQTAMILEVLLLFNSVAIFIYDLCIFEPINELSEYYKKNGWYPP
                     VHVLSYITFIWMNKLIVETYRNKKIKDPNQLPLPPVDLNIKSISKEFKANWELEKWLN
                     RNSLWRAIWKSFGRTISVAMLYETTSDLLSVVQPQFLRIFIDGLNPETSSKYPPLNGV
                     FIALTLFVISVVSVFLTNQFYIGIFEAGLGIRGSLASLVYQKSLRLTLAERNEKSTGD
                     ILNLMSVDVLRIQRFFENAQTIIGAPIQIIVVLTSLYWLLGKAVIGGLVTMAIMMPIN
                     AFLSRKVKKLSKTQMKYKDMRIKTITELLNAIKSIKLYAWEEPMMARLNHVRNDMELK
                     NFRKIGIVSNLIYFAWNCVPLMVTCSTFGLFSLFSDSPLSPAIVFPSLSLFNILNSAI
                     YSVPSMINTIIETSVSMERLKSFLLSDEIDDSFIERIDPSADERALPAIEMNNITFLW
                     KSKEVLTSSQSGDNLRTDEESIIGSSQIALKNIDHFEAKRGDLVCVVGRVGAGKSTFL
                     KAILGQLPCMSGSRDSIPPKLIIRSSSVAYCSQESWIMNASVRENILFGHKFDQDYYD
                     LTIKACQLLPDLKILPDGDETLVGEKGISLSGGQKARLSLARAVYSRADIYLLDDILS
                     AVDAEVSKNIIEYVLIGKTALLKNKTIILTTNTVSILKHSQMIYALENGEIVEQGNYE
                     DVMNRKNNTSKLKKLLEEFDSPIDNGNESDVQTEHRSESEVDEPLQLKVTESETEDEV
                     VTESELELIKANSRRASLATLRPRPFVGAQLDSVKKTAQKAEKTEVGRVKTKIYLAYI
                     KACGVLGVVLFFLFMILTRVFDLAENFWLKYWSESNEKNGSNERVWMFVGVYSLIGVA
                     SAAFNNLRSIMMLLYCSIRGSKKLHESMAKSVIRSPMTFFETTPVGRIINRFSSDMDA
                     VDSNLQYIFSFFFKSILTYLVTVILVGYNMPWFLVFNMFLVVIYIYYQTFYIVLSREL
                     KRLISISYSPIMSLMSESLNGYSIIDAYDHFERFIYLNYEKIQYNVDFVFNFRSTNRW
                     LSVRLQTIGATIVLATAILALATMNTKRQLSSGMVGLLMSYSLEVTGSLTWIVRTTVT
                     IETNIVSVERIVEYCELPPEAQSINPEKRPDENWPSKGGIEFKNYSTKYRENLDPVLN
                     NINVKIEPCEKVGIVGRTGAGKSTLSLALFRILEPTEGKIIIDGIDISDIGLFDLRSH
                     LAIIPQDAQAFEGTVKTNLDPFNRYSEDELKRAVEQAHLKPHLEKMLHSKPRGDDSNE
                     EDGNVNDILDVKINENGSNLSVGQRQLLCLARALLNRSKILVLDEATASVDMETDKII
                     QDTIRREFKDRTILTIAHRIDTVLDSDKIIVLDQGSVREFDSPSKLLSDKTSIFYSLC
                     EKGGYLK"
     gene            <121322..>121648
                     /gene="EMC6"
                     /locus_tag="YLL014W"
                     /db_xref="GeneID:850646"
     mRNA            <121322..>121648
                     /gene="EMC6"
                     /locus_tag="YLL014W"
                     /product="Emc6p"
                     /transcript_id="NM_001181834.1"
                     /db_xref="GI:296146524"
                     /db_xref="GeneID:850646"
     CDS             121322..121648
                     /gene="EMC6"
                     /locus_tag="YLL014W"
                     /note="Member of conserved ER transmembrane complex;
                     required for efficient folding of proteins in the ER; null
                     mutant displays induction of the unfolded protein
                     response; homologous to worm F33D4.7/EMC-6, fly CG11781,
                     human TMEM93"
                     /codon_start=1
                     /product="Emc6p"
                     /protein_id="NP_013087.1"
                     /db_xref="GI:6323015"
                     /db_xref="SGD:S000003937"
                     /db_xref="GeneID:850646"
                     /translation="MSSNEEVFTQINATANVVDNKKRLLFVQDSSALVLGLVAGFLQI
                     ESVHGFIWFLILYNLINVIYIVWICQLQPGKFYQSPLHDIFFESFFREITGFVMAWTF
                     GYALIG"
     gene            complement(<122075..>124714)
                     /gene="PUF3"
                     /locus_tag="YLL013C"
                     /db_xref="GeneID:850647"
     mRNA            complement(<122075..>124714)
                     /gene="PUF3"
                     /locus_tag="YLL013C"
                     /product="Puf3p"
                     /transcript_id="NM_001181833.1"
                     /db_xref="GI:296146525"
                     /db_xref="GeneID:850647"
     CDS             complement(122075..124714)
                     /gene="PUF3"
                     /locus_tag="YLL013C"
                     /note="Protein of the mitochondrial outer surface; links
                     the Arp2/3 complex with the mitochore during anterograde
                     mitochondrial movement; also binds to and promotes
                     degradation of mRNAs for select nuclear-encoded
                     mitochondrial proteins"
                     /codon_start=1
                     /product="Puf3p"
                     /protein_id="NP_013088.1"
                     /db_xref="GI:6323016"
                     /db_xref="SGD:S000003936"
                     /db_xref="GeneID:850647"
                     /translation="MEMNMDMDMDMELASIVSSLSALSHSNNNGGQAAAAGIVNGGAA
                     GSQQIGGFRRSSFTTANEVDSEILLLHGSSESSPIFKKTALSVGTAPPFSTNSKKFFG
                     NGGNYYQYRSTDTASLSSASYNNYHTHHTAANLGKNNKVNHLLGQYSASIAGPVYYNG
                     NDNNNSGGEGFFEKFGKSLIDGTRELESQDRPDAVNTQSQFISKSVSNASLDTQNTFE
                     QNVESDKNFNKLNRNTTNSGSLYHSSSNSGSSASLESENAHYPKRNIWNVANTPVFRP
                     SNNPAAVGATNVALPNQQDGPANNNFPPYMNGFPPNQFHQGPHYQNFPNYLIGSPSNF
                     ISQMISVQIPANEDTEDSNGKKKKKANRPSSVSSPSSPPNNSPFPFAYPNPMMFMPPP
                     PLSAPQQQQQQQQQQQQEDQQQQQQQENPYIYYPTPNPIPVKMPKDEKTFKKRNNKNH
                     PANNSNNANKQANPYLENSIPTKNTSKKNASSKSNESTANNHKSHSHSHPHSQSLQQQ
                     QQTYHRSPLLEQLRNSSSDKNSNSNMSLKDIFGHSLEFCKDQHGSRFIQRELATSPAS
                     EKEVIFNEIRDDAIELSNDVFGNYVIQKFFEFGSKIQKNTLVDQFKGNMKQLSLQMYA
                     CRVIQKALEYIDSNQRIELVLELSDSVLQMIKDQNGNHVIQKAIETIPIEKLPFILSS
                     LTGHIYHLSTHSYGCRVIQRLLEFGSSEDQESILNELKDFIPYLIQDQYGNYVIQYVL
                     QQDQFTNKEMVDIKQEIIETVANNVVEYSKHKFASNVVEKSILYGSKNQKDLIISKIL
                     PRDKNHALNLEDDSPMILMIKDQFANYVIQKLVNVSEGEGKKLIVIAIRAYLDKLNKS
                     NSLGNRHLASVEKLAALVENAEV"
     gene            <125534..>127255
                     /gene="YEH1"
                     /locus_tag="YLL012W"
                     /db_xref="GeneID:850648"
     mRNA            <125534..>127255
                     /gene="YEH1"
                     /locus_tag="YLL012W"
                     /product="Yeh1p"
                     /transcript_id="NM_001181832.1"
                     /db_xref="GI:296146526"
                     /db_xref="GeneID:850648"
     CDS             125534..127255
                     /gene="YEH1"
                     /locus_tag="YLL012W"
                     /EC_number="3.1.1.13"
                     /note="Steryl ester hydrolase; one of three gene products
                     (Yeh1p, Yeh2p, Tgl1p) responsible for steryl ester
                     hydrolase activity and involved in sterol homeostasis;
                     localized to lipid particle membranes; YEH1 has a paralog,
                     YEH2, that arose from the whole genome duplication"
                     /codon_start=1
                     /product="Yeh1p"
                     /protein_id="NP_013089.1"
                     /db_xref="GI:6323017"
                     /db_xref="SGD:S000003935"
                     /db_xref="GeneID:850648"
                     /translation="MGVSAVLKRARNLLATFIVCCFMAVVLVLALAHHFINEHRDTRS
                     SSTQIEVDDESKRNVHHDHVLTRTNAYATPYLDLEHDKKNGIVYDHTRTVVRKKNHEV
                     GSSSLHKNLFHKFLTKLIFRFIEKEKVTEGVTQGKFNNSSNEIANHEPVFEKIPVQCD
                     NPLQNLILSEDLTLVADLNYYFNQYNIQIEEFRLETEDGFVIDLWHLIPKYRTTDSDK
                     KKRPPILMLHGLLQSSGSFASNGRKSLAYFLYQSGYDIWLGNNRCGFRPEWNEAKVPT
                     LASRWDWDLREMVKYDLTLLIDTVLAKTQFEKLTLISHSQGTTQGFMGLVNEDKFFPP
                     GSGSKESFFTSKIANYIALAPAVYPGPLLNEKLFVKLMTKEIENPWFFGETSFFEIMM
                     IVRNLCVGESLFSFVCYTIFNYLFDWNDTLWDTALRDRHFLFSPVHVSVKLMQWWLSP
                     DPNKVSFKFGSHKMFPDNVKWFSDASKAPNIYLFVPKQDRLVDGERLINHFVNVESNV
                     NYKIWYIDEYAHIDVLWAHDVIERIGKPILQNLNNYYSKKPSSAFESDCSDTEVETEL
                     EMVAEKA"
     gene            <127523..>128992
                     /gene="SOF1"
                     /locus_tag="YLL011W"
                     /db_xref="GeneID:850649"
     mRNA            <127523..>128992
                     /gene="SOF1"
                     /locus_tag="YLL011W"
                     /product="Sof1p"
                     /transcript_id="NM_001181831.1"
                     /db_xref="GI:296146527"
                     /db_xref="GeneID:850649"
     CDS             127523..128992
                     /gene="SOF1"
                     /locus_tag="YLL011W"
                     /note="Protein required for biogenesis of 40S (small)
                     ribosomal subunit; has similarity to the beta subunit of
                     trimeric G-proteins and the splicing factor Prp4p;
                     essential gene"
                     /codon_start=1
                     /product="Sof1p"
                     /protein_id="NP_013090.1"
                     /db_xref="GI:6323018"
                     /db_xref="SGD:S000003934"
                     /db_xref="GeneID:850649"
                     /translation="MKIKTIKRSADDYVPVKSTQESQMPRNLNPELHPFERAREYTKA
                     LNATKLERMFAKPFVGQLGYGHRDGVYAIAKNYGSLNKLATGSADGVIKYWNMSTREE
                     FVSFKAHYGLVTGLCVTQPRFHDKKPDLKSQNFMLSCSDDKTVKLWSINVDDYSNKNS
                     SDNDSVTNEEGLIRTFDGESAFQGIDSHRENSTFATGGAKIHLWDVNRLKPVSDLSWG
                     ADNITSLKFNQNETDILASTGSDNSIVLYDLRTNSPTQKIVQTMRTNAICWNPMEAFN
                     FVTANEDHNAYYYDMRNLSRSLNVFKDHVSAVMDVDFSPTGDEIVTGSYDKSIRIYKT
                     NHGHSREIYHTKRMQHVFQVKYSMDSKYIISGSDDGNVRLWRSKAWERSNVKTTREKN
                     KLEYDEKLKERFRHMPEIKRISRHRHVPQVIKKAQEIKNIELSSIKRREANERRTRKD
                     MPYISERKKQIVGTVHKYEDSGRDRKRRKEDDKRDTQEK"
     gene            complement(<129330..>130613)
                     /gene="PSR1"
                     /locus_tag="YLL010C"
                     /db_xref="GeneID:850650"
     mRNA            complement(<129330..>130613)
                     /gene="PSR1"
                     /locus_tag="YLL010C"
                     /product="Psr1p"
                     /transcript_id="NM_001181830.1"
                     /db_xref="GI:296146528"
                     /db_xref="GeneID:850650"
     CDS             complement(129330..130613)
                     /gene="PSR1"
                     /locus_tag="YLL010C"
                     /EC_number="3.1.3.-"
                     /note="Plasma membrane associated protein phosphatase;
                     involved in the general stress response; required along
                     with binding partner Whi2p for full activation of
                     STRE-mediated gene expression, possibly through
                     dephosphorylation of Msn2p; PSR1 has a paralog, PSR2, that
                     arose from the whole genome duplication"
                     /codon_start=1
                     /product="Psr1p"
                     /protein_id="NP_013091.1"
                     /db_xref="GI:6323019"
                     /db_xref="SGD:S000003933"
                     /db_xref="GeneID:850650"
                     /translation="MGFISSILCCSSETTQSNSNSAYRQQQSSSLNKNRSVKHSNTKS
                     RTRGVHQTNSPPSKTNSAATFSSTERSTGKSGISTNDNEKKKPSSPTAAVTATTTNNM
                     TKVEKRISKDDLYEEKYEVDEDEEIDDEDNRRSRGIVQEKGDAVKDTSRQKKQQQQQQ
                     QQSQPQPQPQSQSQSQSQSQSQQRGPTVQVSSDHLIQDMNLSRVSSSSQASETSNDAD
                     DEDDEDEEYIDLTLLQQGQYHAPGYNTLLPPQDESTKGKKCLILDLDETLVHSSFKYL
                     RSADFVLSVEIDDQVHNVYVIKRPGVEEFLERVGKLFEVVVFTASVSRYGDPLLDILD
                     TDKVIHHRLFREACYNYEGNYIKNLSQIGRPLSDIIILDNSPASYIFHPQHAIPISSW
                     FSDTHDNELLDIIPLLEDLSVKTSLDVGKILDVTI"
     gene            complement(<131205..>131414)
                     /gene="COX17"
                     /locus_tag="YLL009C"
                     /db_xref="GeneID:850651"
     mRNA            complement(<131205..>131414)
                     /gene="COX17"
                     /locus_tag="YLL009C"
                     /product="copper metallochaperone COX17"
                     /transcript_id="NM_001181829.1"
                     /db_xref="GI:296146529"
                     /db_xref="GeneID:850651"
     CDS             complement(131205..131414)
                     /gene="COX17"
                     /locus_tag="YLL009C"
                     /note="Copper metallochaperone that transfers copper to
                     Sco1p and Cox11p; eventual delivery to cytochrome c
                     oxidase; contains twin cysteine-x9-cysteine motifs"
                     /codon_start=1
                     /product="copper metallochaperone COX17"
                     /protein_id="NP_013092.1"
                     /db_xref="GI:6323020"
                     /db_xref="SGD:S000003932"
                     /db_xref="GeneID:850651"
                     /translation="MTETDKKQEQENHAECEDKPKPCCVCKPEKEERDTCILFNGQDS
                     EKCKEFIEKYKECMKGYGFEVPSAN"
     gene            <131729..>133987
                     /gene="DRS1"
                     /locus_tag="YLL008W"
                     /db_xref="GeneID:850652"
     mRNA            <131729..>133987
                     /gene="DRS1"
                     /locus_tag="YLL008W"
                     /product="Drs1p"
                     /transcript_id="NM_001181828.1"
                     /db_xref="GI:296146530"
                     /db_xref="GeneID:850652"
     CDS             131729..133987
                     /gene="DRS1"
                     /locus_tag="YLL008W"
                     /EC_number="3.6.4.13"
                     /note="Nucleolar DEAD-box protein required for ribosome
                     assembly and function; including synthesis of 60S
                     ribosomal subunits; constituent of 66S pre-ribosomal
                     particles"
                     /codon_start=1
                     /product="Drs1p"
                     /protein_id="NP_013093.1"
                     /db_xref="GI:6323021"
                     /db_xref="SGD:S000003931"
                     /db_xref="GeneID:850652"
                     /translation="MVVGTKKYSNLDFVPTISDSEDDVPILDSSDDEKVEAKKTTKKR
                     KGKNNKKKVSEGDNLDEDVHEDLDAGFKFDLDADDTTSNFQGWNFLAEGESNKDDAEA
                     FVKKDVDLDKIIRRKGGLVKMAHIDSKQEEETEKEKVEKENDSDDEELAMDGFGMGAP
                     MNNGDENQSEEEEEEEEKEEEEEEEEEQEEMTLEKGGKDDEIDEEDDSEEAKADFYAP
                     ETEGDEAKKQMYENFNSLSLSRPVLKGLASLGYVKPSPIQSATIPIALLGKDIIAGAV
                     TGSGKTAAFMIPIIERLLYKPAKIASTRVIVLLPTRELAIQVADVGKQIARFVSGITF
                     GLAVGGLNLRQQEQMLKSRPDIVIATPGRFIDHIRNSASFNVDSVEILVMDEADRMLE
                     EGFQDELNEIMGLLPSNRQNLLFSATMNSKIKSLVSLSLKKPVRIMIDPPKKAATKLT
                     QEFVRIRKRDHLKPALLFNLIRKLDPTGQKRIVVFVARKETAHRLRIIMGLLGMSVGE
                     LHGSLTQEQRLDSVNKFKNLEVPVLICTDLASRGLDIPKIEVVINYDMPKSYEIYLHR
                     VGRTARAGREGRSVTFVGESSQDRSIVRAAIKSVEENKSLTQGKALGRNVDWVQIEET
                     NKLVESMNDTIEDILVEEKEEKEILRAEMQLRKGENMLKHKKEIQARPRRTWFQSESD
                     KKNSKVLGALSRNKKVTNSKKRKREEAKADGNGARSYRKTKTDRIADQERTFKKQKST
                     NSNKKKGFKSRR"
     gene            complement(<134302..>136299)
                     /locus_tag="YLL007C"
                     /db_xref="GeneID:850653"
     mRNA            complement(<134302..>136299)
                     /locus_tag="YLL007C"
                     /product="hypothetical protein"
                     /transcript_id="NM_001181827.1"
                     /db_xref="GI:296146531"
                     /db_xref="GeneID:850653"
     CDS             complement(134302..136299)
                     /locus_tag="YLL007C"
                     /note="hypothetical protein; green fluorescent protein
                     (GFP)-fusion protein localizes to the cytoplasm; YLL007C
                     is not an essential gene"
                     /codon_start=1
                     /product="hypothetical protein"
                     /protein_id="NP_013094.1"
                     /db_xref="GI:6323022"
                     /db_xref="SGD:S000003930"
                     /db_xref="GeneID:850653"
                     /translation="MKHNRQMPDESLENIKVLLNPKLGKPVKSLTSAQSKACYHTLIS
                     NKNLNKTSDEYEKLLANYILLCDEKYLCKTVIPDSRFWAILCDNCQKLRSETLVANLI
                     RIFNVALKCQDSNKNEVIVSICHISRENSQLIGILLQLLSQRPIHIPLFTDTILCITL
                     FLKCSLTLCETSLSHAVEFVPRILILLFQYNFPASMSELLYIEDLQPLILEEFVPLKQ
                     RLINFLSSVSIDDYSCSLKADLLTAIKDNSVFQKGLEMEMGDLPSINLLNAYDTFTFL
                     NSPNGSFKRLYTEQLLFGENDFPLYEAIFKLSDQFRRLFNLSGKKENQYSDSERDLKL
                     QIATAVLNRQTCFYKTLELFLRFWIESLAKSQSDLVSLLNLAIITLKYVCLSSSDLEA
                     AIQTKSLLKTQVVALDSMRYKFARTLQLDSIKKEQYRTWSSSIASFDTMLSGQVRDYV
                     RHQRLLQLQKGTWVYAENPLNPEAGTPKVYFLIVSDNHANLLAREFETQTNDLPYLFD
                     NKILTSPGSEALANGRTKVVVLKHITSFKSIELTTPSRRTSSNVYIKLDEANVYTGVE
                     LKDRNDRTVLKFYLDTEEGRYIWLDGLKLISPFQHEDISEDTKEQIDTLFDLRKNVQM
                     INLNVRQDIIVPPPEPSDEDEDEEFYNLETLKKVTQNFYFD"
     gene            <136345..>136521
                     /locus_tag="YLL006W-A"
                     /db_xref="GeneID:1466403"
     mRNA            <136345..>136521
                     /locus_tag="YLL006W-A"
                     /product="hypothetical protein"
                     /transcript_id="NM_001184559.1"
                     /db_xref="GI:296146532"
                     /db_xref="GeneID:1466403"
     CDS             136345..136521
                     /locus_tag="YLL006W-A"
                     /note="hypothetical protein; identified by fungal homology
                     and RT-PCR"
                     /codon_start=1
                     /product="hypothetical protein"
                     /protein_id="NP_878116.1"
                     /db_xref="GI:33438828"
                     /db_xref="SGD:S000028560"
                     /db_xref="GeneID:1466403"
                     /translation="MTQLSQSNVERVALVYISVYFFSCISLIVYFFTFCLSVSIPKNR
                     QHPIKIIYNNKCPS"
     gene            <136586..>137866
                     /gene="MMM1"
                     /locus_tag="YLL006W"
                     /gene_synonym="YME6"
                     /db_xref="GeneID:850654"
     mRNA            <136586..>137866
                     /gene="MMM1"
                     /locus_tag="YLL006W"
                     /gene_synonym="YME6"
                     /product="Mmm1p"
                     /transcript_id="NM_001181826.1"
                     /db_xref="GI:296146533"
                     /db_xref="GeneID:850654"
     CDS             136586..137866
                     /gene="MMM1"
                     /locus_tag="YLL006W"
                     /gene_synonym="YME6"
                     /note="ER integral membrane protein, ERMES complex
                     subunit; ERMES links the ER to mitochondria and may
                     promote inter-organellar calcium and phospholipid exchange
                     as well as coordinating mitochondrial DNA replication and
                     growth; required for mitophagy"
                     /codon_start=1
                     /product="Mmm1p"
                     /protein_id="NP_013095.1"
                     /db_xref="GI:6323023"
                     /db_xref="SGD:S000003929"
                     /db_xref="GeneID:850654"
                     /translation="MTDSENESTETDSLMTFDDYISKELPEHLQRLIMENLKGSTTND
                     LKQTSNNSEFNVSKNGSFKGLDDAIQALQMQSVLHPSSLGSLATSSKFSGWSFAQGFF
                     VGQLSIVLLFIFFLKFFIFSDEPSKSKNPKPAASRHRSKFKEYPFISREFLTSLVRKG
                     AKQHYELNEEAENEHLQELALILEKTYYNVDVHPAESLDWFNVLVAQIIQQFRSEAWH
                     RDNILHSLNDFIGRKSPDLPEYLDTIKITELDTGDDFPIFSNCRIQYSPNSGNKKLEA
                     KIDIDLNDHLTLGVETKLLLNYPKPGIAALPINLVVSIVRFQACLTVSLTNAEEFAST
                     SNGSSSENGMEGNSGYFLMFSFSPEYRMEFEIKSLIGSRSKLENIPKIGSVIEYQIKK
                     WFVERCVEPRFQFVRLPSMWPRSKNTREEKPTEL"
     gene            complement(<137940..>140546)
                     /gene="SPO75"
                     /locus_tag="YLL005C"
                     /db_xref="GeneID:850655"
     mRNA            complement(<137940..>140546)
                     /gene="SPO75"
                     /locus_tag="YLL005C"
                     /product="Spo75p"
                     /transcript_id="NM_001181825.1"
                     /db_xref="GI:296146534"
                     /db_xref="GeneID:850655"
     CDS             complement(137940..140546)
                     /gene="SPO75"
                     /locus_tag="YLL005C"
                     /note="Meiosis-specific hypothetical protein; required for
                     spore wall formation during sporulation; dispensable for
                     both nuclear divisions during meiosis"
                     /codon_start=1
                     /product="Spo75p"
                     /protein_id="NP_013096.1"
                     /db_xref="GI:6323024"
                     /db_xref="SGD:S000003928"
                     /db_xref="GeneID:850655"
                     /translation="MNATKELTFNLLNKFQDKERFGSAQRHAGISLKGFISGILFSFL
                     YFLFQLSLFIILRSRFKTIYQANVVLKIHPGSKVCFAKKKIKNYWSLFAFLKQLPGRM
                     LDPMEKFERNERYGLDNYLFLRFLKLLIFFFAVLSIINIPILIPIHYFSRDILKENEG
                     ERYEQSFRTTSKLDKWTMSNLSPNSSNTLICHLFLSIFVVLWFHFILSSELRFVNRLG
                     YSVLTKSKYQNILYLEGFSSKLVTQSISLETFFQPLHSDCFGVTHFIPKNLKKVHKLE
                     IKLNKLQKSKEQIIFEIILEKYFRRVSIHRHLIANHKRFFFSKLKNHLLFQYKKLVFL
                     TQFRISYYCTKIRLRWKKSSIFPLYYPKLYVNTETILERKYRILDKIIRKEKLIKFQV
                     NSLKATSETKQALPDDLSSGTDIYMDKMFITFKSTLLSNVIGELLSYRLPTQNLKVII
                     GPNVNDIIWRNILDSSPLWKSAKYFSANILRIFVIIGWILPVAFLGLISQIPNISSLI
                     PFTKIIHFQSPFIREVAKNLIPIVTLIIIIEIVPYFFRWLSYLRGLKTGAQIEADVQN
                     WYFVFVFIHLFVVVTISSGFSIIIERLLNNPVSIPALLANDLPKCANFFCSFVLIRGM
                     AYAGGNLLRIKELLFELFYYKWKRSTPHAQFKRLKTSLFFQLGSIYPIFSVLGCIGII
                     YSVVAPIILLLCCISFSMVFFSFSYLFKYQYNKENYSETFGKLYIQALMQLYAGIYFM
                     EFCLLGLFTLFDQYTLSTIMLVVFALTVITHSKISKQIKSKPQRIPTLEYLSNLTEER
                     KDQFCQESYTFHDIFSICRNSDEIWLPRDKLGISEEEQSFLEKSYHLKFDLNMYSMNL
                     FGDCHLENSHLH"
     rep_origin      138185..139164
                     /note="ARS1207;
                     Putative replication origin; identified in multiple array
                     studies, not yet confirmed by plasmid-based assay"
                     /db_xref="SGD:S000130181"
     gene            <141073..>142923
                     /gene="ORC3"
                     /locus_tag="YLL004W"
                     /db_xref="GeneID:850656"
     mRNA            <141073..>142923
                     /gene="ORC3"
                     /locus_tag="YLL004W"
                     /product="origin recognition complex subunit 3"
                     /transcript_id="NM_001181824.1"
                     /db_xref="GI:296146535"
                     /db_xref="GeneID:850656"
     CDS             141073..142923
                     /gene="ORC3"
                     /locus_tag="YLL004W"
                     /note="Subunit of the origin recognition complex (ORC);
                     ORC directs DNA replication by binding to replication
                     origins and is also involved in transcriptional silencing"
                     /codon_start=1
                     /product="origin recognition complex subunit 3"
                     /protein_id="NP_013097.1"
                     /db_xref="GI:6323025"
                     /db_xref="SGD:S000003927"
                     /db_xref="GeneID:850656"
                     /translation="MSDLNQSKKMNVSEFADAQRSHYTVYPSLPQSNKNDKHIPFVKL
                     LSGKESEVNVEKRWELYHQLHSHFHDQVDHIIDNIEADLKAEISDLLYSETTQKRRCF
                     NTIFLLGSDSTTKIELKDESSRYNVLIELTPKESPNVRMMLRRSMYKLYSAADAEEHP
                     TIKYEDINDEDGDFTEQNNDVSYDLSLVENFKRLFGKDLAMVFNFKDVDSINFNTLDN
                     FIILLKSAFKYDHVKISLIFNINTNLSNIEKNLRQSTIRLLKRNYHKLDVSSNKGFKY
                     GNQIFQSFLDTVDGKLNLSDRFVEFILSKMANNTNHNLQLLTKMLDYSLMSYFFQNAF
                     SVFIDPVNVDFLNDDYLKILSRCPTFMFFVEGLIKQHAPADEILSLLTNKNRGLEEFF
                     VEFLVRENPINGHAKFVARFLEEELNITNFNLIELYHNLLIGKLDSYLDRWSACKEYK
                     DRLHFEPIDTIFQELFTLDNRSGLLTQSIFPSYKSNIEDNLLSWEQVLPSLDKENYDT
                     LSGDLDKIMAPVLGQLFKLYREANMTINIYDFYIAFRETLPKEEILNFIRKDPSNTKL
                     LELAETPDAFDKVALILFMQAIFAFENMGLIKFQSTKSYDLVEKCVWRGI"
     gene            <143201..>146041
                     /gene="SFI1"
                     /locus_tag="YLL003W"
                     /db_xref="GeneID:850657"
     mRNA            <143201..>146041
                     /gene="SFI1"
                     /locus_tag="YLL003W"
                     /product="Sfi1p"
                     /transcript_id="NM_001181823.1"
                     /db_xref="GI:296146536"
                     /db_xref="GeneID:850657"
     CDS             143201..146041
                     /gene="SFI1"
                     /locus_tag="YLL003W"
                     /note="Centrin (Cdc31p)-binding protein required for SPB
                     duplication; localizes to the half-bridge of the spindle
                     pole body (SPB); required for progression through G(2)-M
                     transition; has similarity to Xenopus laevis XCAP-C"
                     /codon_start=1
                     /product="Sfi1p"
                     /protein_id="NP_013098.1"
                     /db_xref="GI:6323026"
                     /db_xref="SGD:S000003926"
                     /db_xref="GeneID:850657"
                     /translation="MGKFGTTNKSTENLLRDKFVPETSPTNIPTDVLIKQGQITDSTE
                     SLIHGGAERYIVNALKPIELNKTEGFFEDPPFHLPSPPVDSTNLEYEDVTDLPKNGLR
                     YDLNDISVEVIEDLYRQIEAFLVHFKLSRSFLQIFKNYVNILIQEGINPLRDEYFTIL
                     EDELKGFFTFNSVIEEILEIFLIHPRNKFIALSLAEYTYAKNKIRRHFNHWKTVCELN
                     EEANRFANQAKLRVQEAVFYIWSDKTLKYSQMANDEAESFRNTWLLFRSFQQWITLTQ
                     TLKEQSRLADQAFLNKMFRKILKAQEHWKHLETVNTDNIKKIFLRTTFHIWKLRHKEI
                     NYHGLERRIFERIKQKVINYEYNKSIAEKVRSFSLQRKYLNKWEKKNIENEDKLGALY
                     ELENKFIKQKFFRKLNRSFQHSQQEAIAKSKLNQTLLRCVFEKMWLKRFEDHLHLYSI
                     VSLKEANLVKRIFHSWKKLLYIDLKASDYSRTNLLKSSLRSWKLEVKLKIFEQKCKKS
                     IQASAYRTWRKRIQYGKISSEHVKTAFCAKYLGVWKRRMLQMNSMNDEASKFYEEGLV
                     NECLAIWKERLIKTKELEDRYNFLCKTHAILTVKRTLMHIDNVHLLYTKLAPSMDRVK
                     LSKAFLKWRKATRFKVRHKLNDILHVYEKSKERELQSQLFNAWRNRFCFYTEECNIQA
                     ISKRNYQLEKMVLKKFRERLLEIVKSEELADEVREEFVLVKTFYIWKTHLDEIFYMST
                     LLEQSEANKQFIITSKFLKMWSLRFLKIKRNDETVEVFRHRWDRATVRGLLLLWKNRS
                     DSSPKRRKDFNLKHELKTPIRSDSQNASTIPGSERIKQHRMEAMKSHYSRARRAIPSP
                     VKSSSVLDSTAKKQINLESTTGLNGSPTRGKPLRYSPRRTTRNMPSKVDHIDFGRIPA
                     VPFSLSANSPKIDQDMDYIREHDKSPLSRKRQ"
     gene            <146291..>147601
                     /gene="RTT109"
                     /locus_tag="YLL002W"
                     /gene_synonym="KIM2; REM50"
                     /db_xref="GeneID:850658"
     mRNA            <146291..>147601
                     /gene="RTT109"
                     /locus_tag="YLL002W"
                     /gene_synonym="KIM2; REM50"
                     /product="Rtt109p"
                     /transcript_id="NM_001181822.1"
                     /db_xref="GI:296146537"
                     /db_xref="GeneID:850658"
     CDS             146291..147601
                     /gene="RTT109"
                     /locus_tag="YLL002W"
                     /gene_synonym="KIM2; REM50"
                     /EC_number="2.3.1.48"
                     /note="Histone acetyltransferase; critical for cell
                     survival in the presence of DNA damage during S phase;
                     prevents hyper-amplification of rDNA; acetylates H3-K56
                     and H3-K9; involved in non-homologous end joining and in
                     regulation of Ty1 transposition; interacts physically with
                     Vps75p"
                     /codon_start=1
                     /product="Rtt109p"
                     /protein_id="NP_013099.1"
                     /db_xref="GI:6323027"
                     /db_xref="SGD:S000003925"
                     /db_xref="GeneID:850658"
                     /translation="MSLNDFLSSVLPVSEQFEYLSLQSIPLETHAVVTPNKDDKRVPK
                     STIKTQHFFSLFHQGKVFFSLEVYVYVTLWDEADAERLIFVSKADTNGYCNTRVSVRD
                     ITKIILEFILSIDPNYYLQKVKPAIRSYKKISPELISAASTPARTLRILARRLKQSGS
                     TVLKEIESPRFQQDLYLSFTCPREILTKICLFTRPASQYLFPDSSKNSKKHILNGEEL
                     MKWWGFILDRLLIECFQNDTQAKLRIPGEDPARVRSYLRGMKYPLWQVGDIFTSKENS
                     LAVYNIPLFPDDPKARFIHQLAEEDRLLKVSLSSFWIELQERQEFKLSVTSSVMGISG
                     YSLATPSLFPSSADVIVPKSRKQFRAIKKYITGEEYDTEEGAIEAFTNIRDFLLLRMA
                     TNLQSLTGKREHRERNQPVPASNINTLAITMLKPRKKAKALPKT"
     gene            <147890..>150163
                     /gene="DNM1"
                     /locus_tag="YLL001W"
                     /db_xref="GeneID:850686"
     mRNA            <147890..>150163
                     /gene="DNM1"
                     /locus_tag="YLL001W"
                     /product="dynamin-related GTPase DNM1"
                     /transcript_id="NM_001181821.1"
                     /db_xref="GI:296146538"
                     /db_xref="GeneID:850686"
     CDS             147890..150163
                     /gene="DNM1"
                     /locus_tag="YLL001W"
                     /EC_number="3.6.5.5"
                     /note="Dynamin-related GTPase involved in mitochondrial
                     organization; required for mitochondrial fission and
                     morphology; assembles on the cytoplasmic face of
                     mitochondrial tubules at sites at which division will
                     occur; also participates in endocytosis and regulating
                     peroxisome abundance"
                     /codon_start=1
                     /product="dynamin-related GTPase DNM1"
                     /protein_id="NP_013100.1"
                     /db_xref="GI:6323028"
                     /db_xref="SGD:S000003924"
                     /db_xref="GeneID:850686"
                     /translation="MASLEDLIPTVNKLQDVMYDSGIDTLDLPILAVVGSQSSGKSSI
                     LETLVGRDFLPRGTGIVTRRPLVLQLNNISPNSPLIEEDDNSVNPHDEVTKISGFEAG
                     TKPLEYRGKERNHADEWGEFLHIPGKRFYDFDDIKREIENETARIAGKDKGISKIPIN
                     LKVFSPHVLNLTLVDLPGITKVPIGEQPPDIEKQIKNLILDYIATPNCLILAVSPANV
                     DLVNSESLKLAREVDPQGKRTIGVITKLDLMDSGTNALDILSGKMYPLKLGFVGVVNR
                     SQQDIQLNKTVEESLDKEEDYFRKHPVYRTISTKCGTRYLAKLLNQTLLSHIRDKLPD
                     IKTKLNTLISQTEQELARYGGVGATTNESRASLVLQLMNKFSTNFISSIDGTSSDINT
                     KELCGGARIYYIYNNVFGNSLKSIDPTSNLSVLDVRTAIRNSTGPRPTLFVPELAFDL
                     LVKPQIKLLLEPSQRCVELVYEELMKICHKCGSAELARYPKLKSMLIEVISELLRERL
                     QPTRSYVESLIDIHRAYINTNHPNFLSATEAMDDIMKTRRKRNQELLKSKLSQQENGQ
                     TNGINGTSSISSNIDQDSAKNSDYDDDGIDAESKQTKDKFLNYFFGKDKKGQPVFDAS
                     DKKRSIAGDGNIEDFRNLQISDFSLGDIDDLENAEPPLTEREELECELIKRLIVSYFD
                     IIREMIEDQVPKAVMCLLVNYCKDSVQNRLVTKLYKETLFEELLVEDQTLAQDRELCV
                     KSLGVYKKAATLISNIL"
     centromere      complement(150828..150947)
                     /note="CEN12; Chromosome XII centromere"
                     /db_xref="SGD:S000006473"
     centromere      complement(150828..150852)
                     /note="CEN12_CDEIII of CEN12"
     centromere      complement(150853..150937)
                     /note="CEN12_CDEII of CEN12"
     centromere      complement(150938..150947)
                     /note="CEN12_CDEI of CEN12"
     rep_origin      150947..151389
                     /note="ARS1208;
                     Autonomously Replicating Sequence"
                     /db_xref="SGD:S000114848"
     gene            complement(<151389..>153977)
                     /locus_tag="YLR001C"
                     /db_xref="GeneID:850687"
     mRNA            complement(<151389..>153977)
                     /locus_tag="YLR001C"
                     /product="hypothetical protein"
                     /transcript_id="NM_001181888.1"
                     /db_xref="GI:296146539"
                     /db_xref="GeneID:850687"
     CDS             complement(151389..153977)
                     /locus_tag="YLR001C"
                     /note="hypothetical protein; the authentic, non-tagged
                     protein is detected in highly purified mitochondria in
                     high-throughput studies; predicted to be palmitoylated"
                     /codon_start=1
                     /product="hypothetical protein"
                     /protein_id="NP_013101.1"
                     /db_xref="GI:6323029"
                     /db_xref="SGD:S000003991"
                     /db_xref="GeneID:850687"
                     /translation="MNMAIQTIKYIFWLLPILGLTQALLQNPGDDFPFSTVIDILSEN
                     VEFSTFLRIIQKTGHVQYLNELQNFTLFAPINSAFIKGDQTTDQFEEHFHIEDFLIHD
                     RVLQVRDLENGTYLEKRAAKAPLLLRKHERHCFVNEIAVVEPDLLPSFQNASLQGINN
                     LLLIQPQINELLVQLDEETQDLKIFSDFISSFSNYNAYTNSSTVLVPLDVNFRKFFNT
                     IEINYLLDKYNKLGKSNTISQAKWAADRTSLLQELIIDDVYGGILPKELILENKNNRK
                     LFMKSNSEGTSVSVNNSDYSPISNRIFEIGVVHGFSDLDFLRTHIQFDAEKYLHGLNC
                     SEFVKELYFRDLEKFIQNGRKITIFVPQASFNEDRGYTKPSLLYHFVEGKIDLEQDFS
                     SLRPIQYAPTQIYDSAFCSSAKRLGGHCQKFKITRSNKGYYINGRFKILNTKPYEIGN
                     TSIYSIDDDLQLPGDLVLSLAPENHCSISLMLLKELNLLDLPSNHKGYTILLPCMNSW
                     DNNDLTIDYLRSNKTALNLLMRNLIFEDLIYSNNYSISTTVKNLYGNSVSIGVQKIVG
                     SQNLTKISVSTIKESIIIEESSDIFFNQGVIHPIDQLDFPVDLEISLKELIETTGTKE
                     IFDFFNLFYDLSSIIWNNEEYSLLVPTASSIPLSGITANSTNLRKFLELHLIPANVTQ
                     NLLDCNGSISTKLGTKLNCRKDHLDNVFVSIQGDWTKEVRVLKTGCTTNLKSSCIFLI
                     DKPISLSWLNSEKYHLRLPGIAVGFGVIIGVTIAISLLFCIIITRGGKVKDKNQRGRN
                     DRATTPLIQHSPIIHNPSYSATAHLSPLSQPTFEGSYSVNAIQTPRDIRRVGSDQKGG
                     RSVSTS"
     gene            complement(<154343..>156334)
                     /gene="NOC3"
                     /locus_tag="YLR002C"
                     /db_xref="GeneID:850688"
     mRNA            complement(<154343..>156334)
                     /gene="NOC3"
                     /locus_tag="YLR002C"
                     /product="Noc3p"
                     /transcript_id="NM_001181889.1"
                     /db_xref="GI:296146540"
                     /db_xref="GeneID:850688"
     CDS             complement(154343..156334)
                     /gene="NOC3"
                     /locus_tag="YLR002C"
                     /note="Subunit of a nuclear complex with Noc2p and
                     pre-replicative complexes; the Noc2p-Noc3p complex binds
                     to 66S ribosomal precursors to mediate their maturation
                     and intranuclear transport; binds to chromatin at active
                     replication origins, and is required for pre-RC formation
                     and maintenance during DNA replication licensing"
                     /codon_start=1
                     /product="Noc3p"
                     /protein_id="NP_013102.1"
                     /db_xref="GI:6323030"
                     /db_xref="SGD:S000003992"
                     /db_xref="GeneID:850688"
                     /translation="MAKRNRSQFRIQERTAKKRKHEDSLLEGNVFQNAPEDMDENTIY
                     SAKGSSWDEEEQDYEMVPRKNRSDTSNLVEGLPIKVNGKVERKLHKAQEKPKDDDEED
                     EDSNDSSEDDEGPNEEQEAEAKEDEPDTEEKILQLKEDIADLVTKVMEEPEENTAALG
                     RLCKMVESKNPNTCKFSMLALVPVFKSIIPGYRIRPLTETEKKEKVSKEVSKLRNFEQ
                     ALVYNYKNYVGRLQSLSKTPSNAAPIQVSLGILATQAAKELISTASHFNFRTDIFTLL
                     LRRICKPRISTDPTSIQIIQTFETLLNEDEEGSISFEILRIFNKILKTRNFNIEESVL
                     NMLLSLDVLHDYDPNTKLKGNVSAPKLKKKDRVHLSKKQRKARKEMQQIEEEMRNAEQ
                     AVSAEERERNQSEILKIVFTIYLNILKNNAKTLIGSVLEGLTKFGNMANFDLLGDFLE
                     VMKELISDTEFDNLSSAEVRKALLCIVSAFSLISNTQYMKVNVDLSKFVDGLYALLPY
                     ICLDADIELSYRSLRLADPLNNEIIKPSVNVSTKAELLLKALDHVFFRSKSGTKERAT
                     AFTKRLYMCISHTPEKTSIAILKFIDKLMNRYPEISGLYSSEDRIGNGHFIMEADNPS
                     RSNPEAATLWDNALLEKHYCPVVTKGLRSLSSRSKECSK"
     rep_origin      156648..156884
                     /note="ARS1209;
                     Autonomously Replicating Sequence"
                     /db_xref="SGD:S000118470"
     gene            complement(<156855..>157730)
                     /gene="CMS1"
                     /locus_tag="YLR003C"
                     /db_xref="GeneID:850689"
     mRNA            complement(<156855..>157730)
                     /gene="CMS1"
                     /locus_tag="YLR003C"
                     /product="Cms1p"
                     /transcript_id="NM_001181890.1"
                     /db_xref="GI:296146541"
                     /db_xref="GeneID:850689"
     CDS             complement(156855..157730)
                     /gene="CMS1"
                     /locus_tag="YLR003C"
                     /note="Putative subunit of the 90S preribosome processome
                     complex; overexpression rescues supressor mutant of mcm10;
                     null mutant is viable; relocalizes from nucleus to
                     cytoplasm upon DNA replication stress"
                     /codon_start=1
                     /product="Cms1p"
                     /protein_id="NP_013103.1"
                     /db_xref="GI:6323031"
                     /db_xref="SGD:S000003993"
                     /db_xref="GeneID:850689"
                     /translation="MSNPDDLDDGLAYDFDAEHEVIFDAKDGSPPTKKVQKRSIEQDD
                     DDVDDIDGKKEERNSEDDSNRPISKRQKKLQKKSKLIEKKKEESQYIVSQRKALPASS
                     PEKIIEYLTTLIREKNPDLSVLELEELYFKRNDFLSTEKFDAERRLSNFPAFIQKFSV
                     APKKIVFSMSNIRVADVYRSLNGGKNCVKLFSKSKLKDDIATVERLLTDSSKKSNKNK
                     DSLYFIATPTRMQKIIEATDLLFQGKEKLDIILDASYLDPKDNTILSFENAAVLCQVL
                     KTFLNKKSSVKILLY"
     gene            complement(<157934..>159505)
                     /gene="THI73"
                     /locus_tag="YLR004C"
                     /db_xref="GeneID:850690"
     mRNA            complement(<157934..>159505)
                     /gene="THI73"
                     /locus_tag="YLR004C"
                     /product="Thi73p"
                     /transcript_id="NM_001181891.1"
                     /db_xref="GI:296146542"
                     /db_xref="GeneID:850690"
     CDS             complement(157934..159505)
                     /gene="THI73"
                     /locus_tag="YLR004C"
                     /note="Putative plasma membrane permease; proposed to be
                     involved in carboxylic acid uptake and repressed by
                     thiamine; substrate of Dbf2p/Mob1p kinase; transcription
                     is altered if mitochondrial dysfunction occurs"
                     /codon_start=1
                     /product="Thi73p"
                     /protein_id="NP_013104.1"
                     /db_xref="GI:6323032"
                     /db_xref="SGD:S000003994"
                     /db_xref="GeneID:850690"
                     /translation="MKNMSQRSMDVEKKAANADSCSVSTSSINVDDADVALRFLKQNG
                     LDESSTANEDDVVAGEEANFYGSHELSPKVLRKVDLFILPFLCCTYLLMFLDKALLNY
                     AASMGIKDHLKGNEFSNLGTIFSAAYIFMEPVVTYLIQKFPISKILGTFITVWGIVLA
                     CHAACKTYASLMVVRTLLGLFESSSAVGCIAISGMYYTKSEQSARIGFWATQAGTGYI
                     VGGLISFGFLHYHGTAFTSWQIMFLVVGLVTVAFGVLTFLYLPDNVTNAWFLNKEEKI
                     QVVEHIRANQTGLETKKFKKQQVKELFLHDKFTWPMLLLTACSQISTGAIGTFSVTIT
                     GTFGFDKYETALLQLPIGAITAMIILITTQMLSRWGHITLITTSMYIPAIIGCIVLIS
                     LPLSHKIGNLFSLYLLYSGSCVITNIYIWNSCNTSGYTKRVFRNAITMIVYNVSCIIA
                     PQMFRAYSAPRYIPAKIALLVTQCVCVPLQLYIGYICKKENEKRDKEQEGQERKKYQF
                     LDLTDIENRNFRYIY"
     gene            <160049..>161434
                     /gene="SSL1"
                     /locus_tag="YLR005W"
                     /db_xref="GeneID:850691"
     mRNA            <160049..>161434
                     /gene="SSL1"
                     /locus_tag="YLR005W"
                     /product="TFIIH/NER complex subunit SSL1"
                     /transcript_id="NM_001181892.1"
                     /db_xref="GI:296146543"
                     /db_xref="GeneID:850691"
     CDS             160049..161434
                     /gene="SSL1"
                     /locus_tag="YLR005W"
                     /note="Subunit of the core form of RNA polymerase
                     transcription factor TFIIH; has both protein kinase and
                     DNA-dependent ATPase/helicase activities; essential for
                     transcription and nucleotide excision repair; interacts
                     with Tfb4p"
                     /codon_start=1
                     /product="TFIIH/NER complex subunit SSL1"
                     /protein_id="NP_013105.1"
                     /db_xref="GI:6323033"
                     /db_xref="SGD:S000003995"
                     /db_xref="GeneID:850691"
                     /translation="MAPVVISESEEDEDRVAITRRTKRQVHFDGEGDDRVDQQQQQHS
                     SSHRDRDKHVQRKKKKRLSNRNLQGSNGGYAWEDEIKRSWDLVKVDDEGDMASLVASI
                     VEARKKRTAKKNITPYQRGIIRSLILTLDCSEAMLEKDLRPNRHAMIIQYAIDFVHEF
                     FDQNPISQMGIIIMRNGLAQLVSQVSGNPQDHIDALKSIRKQEPKGNPSLQNALEMAR
                     GLLLPVPAHCTREVLIVFGSLSTTDPGDIHQTIDSLVSEKIRVKVLGLSAQVAICKEL
                     CKATNYGDESFYKILLDETHLKELFNEAVTPLPVNKINKGFTLVKMGFPTRIFEDTPT
                     FCSCHSKLVYGGYFCPNCHSKVCSLPTVCPCCDLMLILSTHLARSYHHLMPLKTFAEV
                     PTTEKFRSEDCFSCQSRFPILKNHKNGKLLTSSRYRCEDCKQEFCVDCDVFIHEILHN
                     CPGCESKPVIT"
     gene            complement(<161755..>163893)
                     /gene="SSK1"
                     /locus_tag="YLR006C"
                     /db_xref="GeneID:850692"
     mRNA            complement(<161755..>163893)
                     /gene="SSK1"
                     /locus_tag="YLR006C"
                     /product="mitogen-activated protein kinase kinase kinase
                     SSK1"
                     /transcript_id="NM_001181893.1"
                     /db_xref="GI:296146544"
                     /db_xref="GeneID:850692"
     CDS             complement(161755..163893)
                     /gene="SSK1"
                     /locus_tag="YLR006C"
                     /note="Cytoplasmic response regulator; part of a
                     two-component signal transducer that mediates osmosensing
                     via a phosphorelay mechanism; required for mitophagy;
                     dephosphorylated form is degraded by the
                     ubiquitin-proteasome system; potential Cdc28p substrate"
                     /codon_start=1
                     /product="mitogen-activated protein kinase kinase kinase
                     SSK1"
                     /protein_id="NP_013106.1"
                     /db_xref="GI:6323034"
                     /db_xref="SGD:S000003996"
                     /db_xref="GeneID:850692"
                     /translation="MLNSALLWKVWLRIDNSTDEVNQPIAVQFDEIDTVDDLKSRFFQ
                     KLSSTRWREINDNASIAIGLYAPKFDNQADNTSSNNTNDNSCRSKSNGAGSGANLSVN
                     SNTKSSVSPTAGSFGLSKDLAKDRNVLQHPKPTQKRGALYDAFAAVPTVAATTNVDFP
                     PNEAPMLSPQRPYSTSPKQFPATTKSPLLRFASVSPYPKFHSDNQIMASAGLTYVSPH
                     NKNKYTRPLIRKGLNFTTESVNDCTYKIIFEPDELAINIYKELFGTMGSQPASQPLLI
                     FSNVNLRQDVPPLDILNVVDYVPTNEEISQQKTQPTDHGAVGVFHLDDHISPGEQGLK
                     QTIGDKADLKGKDGNSSPQEFKLITDEEQLRRASQELKDEEKDAESPWQAILLLPKGY
                     KGGVDFRNKPVAHTDSSFNNEDTITHSELEVNTGSPSQESGSLNEAGIGITQPMSEVQ
                     RRKEDVTPASPILTSSQTPHYSNSLYNAPFAVSSPPDPLPNLFTTTSEKVFPKINVLI
                     VEDNVINQAILGSFLRKHKISYKLAKNGQEAVNIWKEGGLHLIFMDLQLPVLSGIEAA
                     KQIRDFEKQNGIGIQKSLNNSHSNLEKGTSKRFSQAPVIIVALTASNSQMDKRKALLS
                     GCNDYLTKPVNLHWLSKKITEWGCMQALIDFDSWKQGESRMTDSVLVKSPQKPIAPSN
                     PHSFKQATSMTPTHSPVRKNSNLSPTQIEL"
     gene            <164392..>165402
                     /gene="NSE1"
                     /locus_tag="YLR007W"
                     /db_xref="GeneID:850693"
     mRNA            <164392..>165402
                     /gene="NSE1"
                     /locus_tag="YLR007W"
                     /product="Nse1p"
                     /transcript_id="NM_001181894.1"
                     /db_xref="GI:296146545"
                     /db_xref="GeneID:850693"
     CDS             164392..165402
                     /gene="NSE1"
                     /locus_tag="YLR007W"
                     /note="Component of the SMC5-SMC6 complex; this complex
                     plays a key role in the removal of X-shaped DNA structures
                     that arise between sister chromatids during DNA
                     replication and repair"
                     /codon_start=1
                     /product="Nse1p"
                     /protein_id="NP_013107.1"
                     /db_xref="GI:6323035"
                     /db_xref="SGD:S000003997"
                     /db_xref="GeneID:850693"
                     /translation="MEVHEEQVSAPVTGDATAKYLLQYILSARGICHENALILALMRL
                     ETDASTLNTEWSIQQWVDKLNDYINAINVKLNLLGYKIIRINHGIGRNAVTLKAKQNF
                     ESFEDNTAIRAHNNDYAVLQSIVLPESNRFFVYVNLASTEETKLATRFNQNEIEFMKW
                     AIEQFMISGETIVEGPALETSIIVKEVNRILVAATGDSNLAKWRKFSTFTVGSTNLFQ
                     FQELTATDIEDLLLRLCELKWFYRTQEGKFGIDLRCIAELEEYLTSMYNLNTCQNCHK
                     LAIQGVRCGNESCREENEETGENSLSQIWHVDCFKHYITHVSKNCDRCGSSLITEGVY
                     VI"
     gene            complement(<165577..>166083)
                     /gene="PAM18"
                     /locus_tag="YLR008C"
                     /gene_synonym="TIM14"
                     /db_xref="GeneID:850694"
     mRNA            complement(<165577..>166083)
                     /gene="PAM18"
                     /locus_tag="YLR008C"
                     /gene_synonym="TIM14"
                     /product="Pam18p"
                     /transcript_id="NM_001181895.1"
                     /db_xref="GI:296146546"
                     /db_xref="GeneID:850694"
     CDS             complement(165577..166083)
                     /gene="PAM18"
                     /locus_tag="YLR008C"
                     /gene_synonym="TIM14"
                     /note="Subunit of the import motor (PAM complex); the PAM
                     complex is a  component of the Translocase of the Inner
                     Mitochondrial membrane (TIM23 complex); essential
                     J-protein cochaperone that stimulates Ssc1p ATPase
                     activity to drive import; inhibited by Pam16p"
                     /codon_start=1
                     /product="Pam18p"
                     /protein_id="NP_013108.1"
                     /db_xref="GI:6323036"
                     /db_xref="SGD:S000003998"
                     /db_xref="GeneID:850694"
                     /translation="MSSQSNTGNSIEAPQLPIPGQTNGSANVTVDGAGVNVGIQNGSQ
                     GQKTGMDLYFDQALNYMGEHPVITGFGAFLTLYFTAGAYKSISKGLNGGKSTTAFLKG
                     GFDPKMNSKEALQILNLTENTLTKKKLKEVHRKIMLANHPDKGGSPFLATKINEAKDF
                     LEKRGISK"
     gene            <166537..>167136
                     /gene="RLP24"
                     /locus_tag="YLR009W"
                     /db_xref="GeneID:850695"
     mRNA            <166537..>167136
                     /gene="RLP24"
                     /locus_tag="YLR009W"
                     /product="Rlp24p"
                     /transcript_id="NM_001181896.1"
                     /db_xref="GI:296146547"
                     /db_xref="GeneID:850695"
     CDS             166537..167136
                     /gene="RLP24"
                     /locus_tag="YLR009W"
                     /note="Essential protein required for ribosomal large
                     subunit biogenesis; associated with pre-60S ribosomal
                     subunits; stimulates the ATPase activity of Afg2p, which
                     is required for release of Rlp24p from the pre-60S
                     particle; has similarity to Rpl24Ap and Rpl24Bp"
                     /codon_start=1
                     /product="Rlp24p"
                     /protein_id="NP_013109.1"
                     /db_xref="GI:6323037"
                     /db_xref="SGD:S000003999"
                     /db_xref="GeneID:850695"
                     /translation="MRIYQCHFCSSPCYPGHGIMFVRNDAKEFRFCRSKCHKAFKQRR
                     NPRKLKWTKAFRKAAGKELAVDSTLTFAQRRNVPVRYNRELVATTLKAMARIEEIRQK
                     RERAFYKNRMRGNKEKDFLRDKKLVESNPELLRIREVEIARKLAKEQERAESVSEQEE
                     SEEEEEDMEIDSDEEEEEQLEKQKILLKNRRRNTKKIAF"
     gene            complement(<167320..>167802)
                     /gene="TEN1"
                     /locus_tag="YLR010C"
                     /db_xref="GeneID:850696"
     mRNA            complement(<167320..>167802)
                     /gene="TEN1"
                     /locus_tag="YLR010C"
                     /product="Ten1p"
                     /transcript_id="NM_001181897.1"
                     /db_xref="GI:296146548"
                     /db_xref="GeneID:850696"
     CDS             complement(167320..167802)
                     /gene="TEN1"
                     /locus_tag="YLR010C"
                     /note="Protein that regulates telomeric length; protects
                     telomeric ends in a complex with Cdc13p and Stn1p; similar
                     to human Ten1 which is critical for the telomeric function
                     of the CST (Cdc13p-Stn1p-Ten1p) complex"
                     /codon_start=1
                     /product="Ten1p"
                     /protein_id="NP_013110.1"
                     /db_xref="GI:6323038"
                     /db_xref="SGD:S000004000"
                     /db_xref="GeneID:850696"
                     /translation="MSQLVLDLKCLKDKIATNYDIHNNVYGGNGMEPNIIHPSKRFRI
                     VVRLVDFLFCKSDEEFIKGFFCQMIVRNLHCLNSTNGAEEMRLYMSERLFSAHKDDLR
                     LINGQVLDVRIGVWYGIHQSPPIFEIIDFKILSRNDVRDFCEFVKSPLGEKFLNISNS
                     "
     gene            complement(167944..168025)
                     /locus_tag="tS(AGA)L"
                     /db_xref="GeneID:850697"
     tRNA            complement(167944..168025)
                     /locus_tag="tS(AGA)L"
                     /product="tRNA-Ser"
                     /note="Serine tRNA (tRNA-Ser), predicted by tRNAscan-SE
                     analysis"
                     /db_xref="SGD:S000006728"
                     /db_xref="GeneID:850697"
     LTR             complement(168043..168380)
                     /note="Ty3 LTR"
                     /db_xref="SGD:S000007079"
     gene            <169103..>169678
                     /gene="LOT6"
                     /locus_tag="YLR011W"
                     /db_xref="GeneID:850698"
     mRNA            <169103..>169678
                     /gene="LOT6"
                     /locus_tag="YLR011W"
                     /product="Lot6p"
                     /transcript_id="NM_001181898.1"
                     /db_xref="GI:296146549"
                     /db_xref="GeneID:850698"
     CDS             169103..169678
                     /gene="LOT6"
                     /locus_tag="YLR011W"
                     /EC_number="1.5.1.39"
                     /note="FMN-dependent NAD(P)H:quinone reductase; role in
                     apoptosis-like cell death; may be involved in quinone
                     detoxification; expression elevated at low temperature;
                     sequesters the Cin5p transcription factor in the cytoplasm
                     in complex with the proteasome under reducing conditions"
                     /codon_start=1
                     /product="Lot6p"
                     /protein_id="NP_013111.1"
                     /db_xref="GI:6323039"
                     /db_xref="SGD:S000004001"
                     /db_xref="GeneID:850698"
                     /translation="MKVGIIMGSVRAKRVCPEIAAYVKRTIENSEELIDQKLKIQVVD
                     LQQIALPLYEDDDELIPAQIKSVDEYADSKTRSWSRIVNALDIIVFVTPQYNWGYPAA
                     LKNAIDRLYHEWHGKPALVVSYGGHGGSKCNDQLQEVLHGLKMNVIGGVAVKIPVGTI
                     PLPEDIVPQLSVHNEEILQLLASCIETTRNK"
     gene            complement(<169982..>170281)
                     /locus_tag="YLR012C"
                     /db_xref="GeneID:850699"
     mRNA            complement(<169982..>170281)
                     /locus_tag="YLR012C"
                     /product="hypothetical protein"
                     /transcript_id="NM_001181899.1"
                     /db_xref="GI:296146550"
                     /db_xref="GeneID:850699"
     CDS             complement(169982..170281)
                     /locus_tag="YLR012C"
                     /note="hypothetical protein; YLR012C is not an essential
                     gene"
                     /codon_start=1
                     /product="hypothetical protein"
                     /protein_id="NP_013112.2"
                     /db_xref="GI:37362676"
                     /db_xref="SGD:S000004002"
                     /db_xref="GeneID:850699"
                     /translation="MKTVYYKEITYQQYLQLQPEQQEKYLALCQKDFEQETERIAFDR
                     QGGVPGIARKFAQEEVAWFDRVTTWSYMNAYIPSYRRRRNLLKIDMLKMSNAEEY"
     gene            <171339..>171764
                     /gene="GAT3"
                     /locus_tag="YLR013W"
                     /db_xref="GeneID:850700"
     mRNA            <171339..>171764
                     /gene="GAT3"
                     /locus_tag="YLR013W"
                     /product="Gat3p"
                     /transcript_id="NM_001181900.1"
                     /db_xref="GI:296146551"
                     /db_xref="GeneID:850700"
     CDS             171339..171764
                     /gene="GAT3"
                     /locus_tag="YLR013W"
                     /note="Protein containing GATA family zinc finger motifs;
                     involved in spore wall assembly; sequence similarity to
                     GAT4, and the double mutant gat3 gat4 exhibits reduced
                     dityrosine fluorescence relative to the single mutants"
                     /codon_start=1
                     /product="Gat3p"
                     /protein_id="NP_013113.1"
                     /db_xref="GI:6323041"
                     /db_xref="SGD:S000004003"
                     /db_xref="GeneID:850700"
                     /translation="MNIKTLCHPEYKRISVESLLNPVEETIDCEKPHSQTKINTAKPI
                     SASLYVTTNNTAVVQHNVQKRKGVTRRCPQCAVIKTSPQWREGPDGEVTLCNACGLFY
                     RKIFLVFGKDLAKRYFNEIKGVSVKRKVPKSLYGVTRTR"
     gene            complement(<172268..>174982)
                     /gene="PPR1"
                     /locus_tag="YLR014C"
                     /db_xref="GeneID:850701"
     mRNA            complement(<172268..>174982)
                     /gene="PPR1"
                     /locus_tag="YLR014C"
                     /product="Ppr1p"
                     /transcript_id="NM_001181901.1"
                     /db_xref="GI:296146552"
                     /db_xref="GeneID:850701"
     CDS             complement(172268..174982)
                     /gene="PPR1"
                     /locus_tag="YLR014C"
                     /note="Zinc finger transcription factor; contains a
                     Zn(2)-Cys(6) binuclear cluster domain, positively
                     regulates transcription of URA1, URA3, URA4, and URA10,
                     which are involved in de novo pyrimidine biosynthesis, in
                     response to pyrimidine starvation; activity may be
                     modulated by interaction with Tup1p"
                     /codon_start=1
                     /product="Ppr1p"
                     /protein_id="NP_013114.1"
                     /db_xref="GI:6323042"
                     /db_xref="SGD:S000004004"
                     /db_xref="GeneID:850701"
                     /translation="MKQKKFNSKKSNRTDLSKRGDSPNIGISKSRTACKRCRLKKIKC
                     DQEFPSCKRCAKLEVPCVSLDPATGKDVPRSYVFFLEDRLAVMMRVLKEYGVDPTKIR
                     GNIPATSDDEPFDLKKYSSVSSLGEEGILPHNGLLADYLVQKGNSMASSAITSKSMAS
                     PQTINVQRKEFLVNSKKQDGSALLPETGSPMTSDARAEELRRCNKEISALGTMRESSF
                     NSFLGDSSGISFAKLVFTATNFRQDSGDDVLDEDIKQREQKYNGYAEAENNPHFDPLE
                     LPPRHAAEVMISRFFVDTNSQLPLLHRELFLKKYFEPIYGPWNPNIALASDQTGINSA
                     FEIPITSAFSAHTEPKRENVTEKIDVCSSVDVPWYDTWETSQKVNMRPIVELPTKFHI
                     PYFFLNIIFAIGHATQVLKSDITTVATYKRRATKYIASLFSSSDRLEALAGTLLMVIY
                     SIMRPNVPGVWYTMGSVLRLTVDLGLHSEKINKNYDAFTREIRRRLFWCVYSLDRQIC
                     SYFGRPFGIPEESITTRYPSLLDDSFITLTNREIDDYSDLPSPNPSSKVIALAMYKIR
                     RIQASIVRILYAPGAELPRRFMDLESWRIETYNELERWFQVDVPKNFEMMNCKFNSIW
                     FDLNYHYSKSILYGLSPKFPTLNDTAFKIVLDSTKGTIDVFYNLCVNKKIGYTWVAVH
                     NMFMTGMTYLYVNFYSKNNINDCQEKVSEYTEKVLIVLKNLIGFCESAKTCYTSYKIL
                     SSVVIKLKFMQINDAKGIFSDSNPLTSQANRMSSYDKKTNVLGFDDGTFDNKVFNRTN
                     FEEKAPFDIPLDEFFTELEKHSNVSQFNTLDVSEGNQVINESASTNTSSALNCQSYTN
                     NQDIMDILFQVTSGSVWDEFFVRSGNGNEGESSYDISKGKNSESGGIF"
     gene            <175227..>176744
                     /gene="BRE2"
                     /locus_tag="YLR015W"
                     /gene_synonym="CPS60"
                     /db_xref="GeneID:850702"
     mRNA            <175227..>176744
                     /gene="BRE2"
                     /locus_tag="YLR015W"
                     /gene_synonym="CPS60"
                     /product="Bre2p"
                     /transcript_id="NM_001181902.1"
                     /db_xref="GI:296146553"
                     /db_xref="GeneID:850702"
     CDS             175227..176744
                     /gene="BRE2"
                     /locus_tag="YLR015W"
                     /gene_synonym="CPS60"
                     /note="Subunit of COMPASS (Set1C) complex; COMPASS
                     methylates Lys4 of histone H3 and functions in silencing
                     at telomeres; has a C-terminal Sdc1 Dpy-30 Interaction
                     (SDI) domain that mediates binding to Sdc1p; similar to
                     trithorax-group protein ASH2L"
                     /codon_start=1
                     /product="Bre2p"
                     /protein_id="NP_013115.1"
                     /db_xref="GI:6323043"
                     /db_xref="SGD:S000004005"
                     /db_xref="GeneID:850702"
                     /translation="MKLGIIPYQEGTDIVYKNALQGQQEGKRPNLPQMEATHQIKSSV
                     QGTSYEFVRTEDIPLNRRHFVYRPCSANPFFTILGYGCTEYPFDHSGMSVMDRSEGLS
                     ISRDGNDLVSVPDQYGWRTARSDVCIKEGMTYWEVEVIRGGNKKFADGVNNKENADDS
                     VDEVQSGIYEKMHKQVNDTPHLRFGVCRREASLEAPVGFDVYGYGIRDISLESIHEGK
                     LNCVLENGSPLKEGDKIGFLLSLPSIHTQIKQAKEFTKRRIFALNSHMDTMNEPWRED
                     AENGPSRKKLKQETTNKEFQRALLEDIEYNDVVRDQIAIRYKNQLFFEATDYVKTTKP
                     EYYSSDKRERQDYYQLEDSYLAIFQNGKYLGKAFENLKPLLPPFSELQYNEKFYLGYW
                     QHGEARDESNDKNTTSAKKKKQQQKKKKGLILRNKYVNNNKLGYYPTISCFNGGTARI
                     ISEEDKLEYLDQIRSAYCVDGNSKVNTLDTLYKEQIAEDIVWDIIDELEQIALQQ"
     gene            complement(<176802..>177416)
                     /gene="PML1"
                     /locus_tag="YLR016C"
                     /db_xref="GeneID:850703"
     mRNA            complement(<176802..>177416)
                     /gene="PML1"
                     /locus_tag="YLR016C"
                     /product="Pml1p"
                     /transcript_id="NM_001181903.1"
                     /db_xref="GI:296146554"
                     /db_xref="GeneID:850703"
     CDS             complement(176802..177416)
                     /gene="PML1"
                     /locus_tag="YLR016C"
                     /note="Subunit of the RES complex; RES complex is required
                     for nuclear retention of unspliced pre-mRNAs; acts in the
                     same pathway as Pml39p and Mlp1p"
                     /codon_start=1
                     /product="Pml1p"
                     /protein_id="NP_013116.1"
                     /db_xref="GI:6323044"
                     /db_xref="SGD:S000004006"
                     /db_xref="GeneID:850703"
                     /translation="MFHRRKRPYNTRNYGHDDKKFKSQYIDIMPDFSPSGLLELESNN
                     KEGIALKHVEPQDAISPDNYMDMLGLEARDRTMYELVIYRKNDKDKGPWKRYDLNGRS
                     CYLVGRELGHSLDTDLDDRTEIVVADIGIPEETSSKQHCVIQFRNVRGILKCYVMDLD
                     SSNGTCLNNVVIPGARYIELRSGDVLTLSEFEEDNDYELIFMNV"
     gene            <177608..>178621
                     /gene="MEU1"
                     /locus_tag="YLR017W"
                     /db_xref="GeneID:850704"
     mRNA            <177608..>178621
                     /gene="MEU1"
                     /locus_tag="YLR017W"
                     /product="S-methyl-5-thioadenosine phosphorylase"
                     /transcript_id="NM_001181904.1"
                     /db_xref="GI:296146555"
                     /db_xref="GeneID:850704"
     CDS             177608..178621
                     /gene="MEU1"
                     /locus_tag="YLR017W"
                     /EC_number="2.4.2.28"
                     /note="Methylthioadenosine phosphorylase (MTAP); catalyzes
                     the initial step in the methionine salvage pathway;
                     affects polyamine biosynthesis through regulation of
                     ornithine decarboxylase (Spe1p) activity; regulates ADH2
                     gene expression"
                     /codon_start=1
                     /product="S-methyl-5-thioadenosine phosphorylase"
                     /protein_id="NP_013117.1"
                     /db_xref="GI:6323045"
                     /db_xref="SGD:S000004007"
                     /db_xref="GeneID:850704"
                     /translation="MNRIKNTFSVAKRLKLSKVMTNSELPSIFEGTVDLGIIGGTGLY
                     NLDCLEPIALLPPMVTPWGTTSSPVTISQFVGTNSHFHVAFIARHGINHEYPPTKVPF
                     RANMAALKNLNCKAVLSFSAVGSLQPHIKPRDFVLPQQIIDRTKGIRHSSYFNDEGLV
                     GHVGFGQPFSQKFAEYIYQFKNEITNPESEEPCHLHYDKDMTVVCMEGPQFSTRAESK
                     MYRMFGGHVINMSVIPEAKLARECELPYQMICMSTDYDAWRDEAEPVTVETVIGNLTN
                     NGRNANILASKIIVSMAKEIPEFMHTGDGLRGSIKKSISTKPEAMSKETLERLRYLFP
                     NYW"
     gene            complement(<178707..>179606)
                     /gene="POM34"
                     /locus_tag="YLR018C"
                     /db_xref="GeneID:850705"
     mRNA            complement(<178707..>179606)
                     /gene="POM34"
                     /locus_tag="YLR018C"
                     /product="Pom34p"
                     /transcript_id="NM_001181905.1"
                     /db_xref="GI:296146556"
                     /db_xref="GeneID:850705"
     CDS             complement(178707..179606)
                     /gene="POM34"
                     /locus_tag="YLR018C"
                     /note="Subunit of the transmembrane ring of the nuclear
                     pore complex (NPC); contributes to nucleocytoplasmic
                     transport, NPC biogenesis and spindle pole body
                     duplication"
                     /codon_start=1
                     /product="Pom34p"
                     /protein_id="NP_013118.1"
                     /db_xref="GI:6323046"
                     /db_xref="SGD:S000004008"
                     /db_xref="GeneID:850705"
                     /translation="MKIQAGQLGLDDNDVPGPLPDTDSKPSSQSQNDTPMFKLGNFES
                     PVLKELSRRTVNKEMETQRIMTNVIAFAFWNLLVKFIKFFWNNTHVGRQFCNRLSRIH
                     LYMLTFHTLKKANIIYHTTFSWLNAELLDYLFHLLISLNILFSLWKLLSTVKVSDLNL
                     TDRQKKLLGVDMQSSVDTGLQPQHPHYVSTSKISQMAQNKTHIPQTNLKNHPAYLFKG
                     LETPLKARQREMAEEQTKLQSQSLHTKNVFGTLQRHSGISSTLVSANNDNNSPHTPVT
                     RKGYIPSSKYAYMMNSQSPRGKI"
     gene            <180288..>181481
                     /gene="PSR2"
                     /locus_tag="YLR019W"
                     /db_xref="GeneID:850706"
     mRNA            <180288..>181481
                     /gene="PSR2"
                     /locus_tag="YLR019W"
                     /product="Psr2p"
                     /transcript_id="NM_001181906.1"
                     /db_xref="GI:296146557"
                     /db_xref="GeneID:850706"
     CDS             180288..181481
                     /gene="PSR2"
                     /locus_tag="YLR019W"
                     /EC_number="3.1.3.-"
                     /note="Plasma membrane phosphatase involved in the general
                     stress response; required with Psr1p and Whi2p for full
                     activation of STRE-mediated gene expression, possibly
                     through dephosphorylation of Msn2p; PSR2 has a paralog,
                     PSR1, that arose from the whole genome duplication"
                     /codon_start=1
                     /product="Psr2p"
                     /protein_id="NP_013119.1"
                     /db_xref="GI:6323047"
                     /db_xref="SGD:S000004009"
                     /db_xref="GeneID:850706"
                     /translation="MGFIANILCCSSDTSKTHRQRQPPETNHNRNRNRKHSSNKAQTQ
                     GRKQKATPNGDKMQYSTPEILLSSSDSGSNAGSKTMQENGNSGNGKLAPLSRDHSNNS
                     YDEEKEYEDYNEGDVEMTEVNNAGEEEEEDDEAKEKQDHVVHEYNVDADRNSSINDEA
                     PPQQGLYQVGQEDMNPQYVASSPDNDLNLIPTTEEDFSDLTHLQPDQYHAPGYDTLLP
                     PKLQEFQQKKCLILDLDETLVHSSFKYMHSADFVLPVEIDDQVHNVYVIKRPGVDEFL
                     NRVSQLYEVVVFTASVSRYANPLLDTLDPNGTIHHRLFREACYNYEGNYIKNLSQIGR
                     PLSETIILDNSPASYIFHPQHAVPISSWFSDTHDNELLDIIPLLEDLSSGNVLDVGSV
                     LDVTI"
     gene            complement(<181789..>183405)
                     /gene="YEH2"
                     /locus_tag="YLR020C"
                     /db_xref="GeneID:850707"
     mRNA            complement(<181789..>183405)
                     /gene="YEH2"
                     /locus_tag="YLR020C"
                     /product="Yeh2p"
                     /transcript_id="NM_001181907.1"
                     /db_xref="GI:296146558"
                     /db_xref="GeneID:850707"
     CDS             complement(181789..183405)
                     /gene="YEH2"
                     /locus_tag="YLR020C"
                     /EC_number="3.1.1.13"
                     /note="Steryl ester hydrolase; catalyzes steryl ester
                     hydrolysis at the plasma membrane; involved in sterol
                     metabolism; YEH2 has a paralog, YEH1, that arose from the
                     whole genome duplication"
                     /codon_start=1
                     /product="Yeh2p"
                     /protein_id="NP_013120.1"
                     /db_xref="GI:6323048"
                     /db_xref="SGD:S000004010"
                     /db_xref="GeneID:850707"
                     /translation="MVNKVVDEVQRLVSAIILTSFMTGLFILSLWKNYVTVHFQHKND
                     PRDTRSSRTKIQPNDKKKKRPARHSRPLSISSTTPLDLQRDQENNIEYDRTVTSKLSM
                     TSNASLSENGDGNANIKMETNVNQAPYAAENPFQNIALAEDTKLVPDLKYYYKEYGID
                     IEEFEVETDDGFIIDLWHFKSRLNDGVEEVKREPILLLHGLLQSCGAFASSGRKSLAY
                     FLYESGFDVWLGNNRCGLNAKWNMKKLGNDHSKKWDWDMHQMVQYDLKALINYVLDST
                     GYAKLSLVAHSQGTTQGFMGLVNGEKLYASDFKLVDKLENFVALAPAVYPGPLLDEKA
                     FVRLMAKGIDSPWYFGRRSFIPLMMTMRKLMVGTKIFSFLSYIMFNYLFDWNDVLWDR
                     VLRDRNFLFSPVHISVKLMQWWLSPLPNKLSFKKGAEKIFPDKKTWFPIAKNDDDSGN
                     NLDNNKLHLNPKRQNSEEFPHIIMFIPKQDRLVDGERLINHFINHEANAVYKIWYIDE
                     YSHLDVLWAHDVIDRIGKPMIENLRFPNAR"
     gene            <183623..>184162
                     /gene="IRC25"
                     /locus_tag="YLR021W"
                     /gene_synonym="DMP2; PBA3; POC3"
                     /db_xref="GeneID:850708"
     mRNA            <183623..>184162
                     /gene="IRC25"
                     /locus_tag="YLR021W"
                     /gene_synonym="DMP2; PBA3; POC3"
                     /product="Irc25p"
                     /transcript_id="NM_001181908.1"
                     /db_xref="GI:296146559"
                     /db_xref="GeneID:850708"
     CDS             183623..184162
                     /gene="IRC25"
                     /locus_tag="YLR021W"
                     /gene_synonym="DMP2; PBA3; POC3"
                     /note="Component of a heterodimeric Poc4p-Irc25p
                     chaperone; involved in assembly of alpha subunits into the
                     20S proteasome; may regulate formation of proteasome
                     isoforms with alternative subunits under different
                     conditions"
                     /codon_start=1
                     /product="Irc25p"
                     /protein_id="NP_013121.1"
                     /db_xref="GI:6323049"
                     /db_xref="SGD:S000004011"
                     /db_xref="GeneID:850708"
                     /translation="MISYEFQTHLPKGKDSSLNASSENKELYVQATHFNNTILLQIRL
                     NGEMDSTYEVSSKGLNPILDINVPLAGNLGNTGGDYDDEEEEFVRDHLSDYQVVTKLG
                     DSADPKVPVVCVQIAELYRRVILPEVSGTMAQDNMQFSLLISMSSKIWRATKEQSADD
                     NDFGKLVFVLKCIKDMYAK"
     gene            complement(<184174..>184926)
                     /gene="SDO1"
                     /locus_tag="YLR022C"
                     /db_xref="GeneID:850709"
     mRNA            complement(<184174..>184926)
                     /gene="SDO1"
                     /locus_tag="YLR022C"
                     /product="Sdo1p"
                     /transcript_id="NM_001181909.1"
                     /db_xref="GI:296146560"
                     /db_xref="GeneID:850709"
     CDS             complement(184174..184926)
                     /gene="SDO1"
                     /locus_tag="YLR022C"
                     /note="Guanine nucleotide exchange factor (GEF) for Ria1p;
                     essential protein involved in ribosome maturation; with
                     Ria1p, promotes release of Tif6p from 60S ribosomal
                     subunits in the cytoplasm so that they can assemble with
                     40S subunits to generate mature ribosomes; ortholog of the
                     human protein (SBDS) responsible for autosomal recessive
                     Shwachman-Bodian-Diamond Syndrome; highly conserved across
                     archaea and eukaryotes"
                     /codon_start=1
                     /product="Sdo1p"
                     /protein_id="NP_013122.1"
                     /db_xref="GI:6323050"
                     /db_xref="SGD:S000004012"
                     /db_xref="GeneID:850709"
                     /translation="MPINQPSGQIKLTNVSLVRLKKARKRFEVACYQNKVQDYRKGIE
                     KDLDEVLQIHQVFMNVSKGLVANKEDLQKCFGTTNVDDVIEEIMHKGEIQLSEKERQL
                     MLNKVNNEMLTIVSAKCINPVSKKRYPPTMIHKALQELKFSPVINKPAKLQALEAIKL
                     LVSKQIIPIVRAKMKVKVAISEPSRQPELIEKISKLIASSPGESTKPELDPWTCTGLI
                     DPVNYRDLMTLCDKKGTVQVLDMAVIDNTTHN"
     gene            complement(<185498..>187129)
                     /gene="IZH3"
                     /locus_tag="YLR023C"
                     /db_xref="GeneID:850710"
     mRNA            complement(<185498..>187129)
                     /gene="IZH3"
                     /locus_tag="YLR023C"
                     /product="Izh3p"
                     /transcript_id="NM_001181910.1"
                     /db_xref="GI:296146561"
                     /db_xref="GeneID:850710"
     CDS             complement(185498..187129)
                     /gene="IZH3"
                     /locus_tag="YLR023C"
                     /note="Membrane protein involved in zinc ion homeostasis;
                     member of the four-protein IZH family, expression induced
                     by zinc deficiency; deletion reduces sensitivity to
                     elevated zinc and shortens lag phase, overexpression
                     reduces Zap1p activity"
                     /codon_start=1
                     /product="Izh3p"
                     /protein_id="NP_013123.1"
                     /db_xref="GI:6323051"
                     /db_xref="SGD:S000004013"
                     /db_xref="GeneID:850710"
                     /translation="MMDSSSKSLTQYIPSPMGSLSRLKQKGVDNFQKVKKSGKSIYNY
                     NYSKFVPHPFSTIDESVKHSESGRYDDLEIIRPTKEKEVTSSVYKRNSGKSLNTESQF
                     SLGDSDAATLVNSVATFKLNNASTSTSLVSSSSTVCSQAKSSLRSPTSRLNDTKIKEE
                     NNYISSVKDYCGPMRKSMVKTEILIEEPLNPTTDIKSFINSYNHGKAYSLGETQHLHY
                     YQLPFPWRENRYIIHGYRFYNTHSKSLLSIFNWYGWHNETSNIWSHLLGAIYIIYLAI
                     YDFPQSEVWRNSQVPPQARWIVFMFLAAALKCMLSSVFWHTFNGTSFLKLRSKFACVD
                     YSGITILITASILTTEFVTMYSCYWAMYTYMSISLALGVFGVFMNWSPRFDRPEARPL
                     RIRFFILLATMGVLSFLHLIFLTDLHYAATLFSPVTYKSVVWYLVGVVFYGSFIPERF
                     RSDVQVDKTIPTNYELSTDLEIITKQREIHFREVPTAHSKCSSCPSHAKSFKSLWWVD
                     YFGCSHTFWHFFVVLGVIGHYRAILDMFAKRWILS"
     gene            complement(<187663..>193281)
                     /gene="UBR2"
                     /locus_tag="YLR024C"
                     /db_xref="GeneID:850711"
     mRNA            complement(<187663..>193281)
                     /gene="UBR2"
                     /locus_tag="YLR024C"
                     /product="putative ubiquitin-protein ligase UBR2"
                     /transcript_id="NM_001181911.2"
                     /db_xref="GI:330443670"
                     /db_xref="GeneID:850711"
     CDS             complement(187663..193281)
                     /gene="UBR2"
                     /locus_tag="YLR024C"
                     /EC_number="6.3.2.-"
                     /note="Cytoplasmic ubiquitin-protein ligase (E3); required
                     for ubiquitylation of Rpn4p; mediates formation of a
                     Mub1p-Ubr2p-Rad6p complex"
                     /codon_start=1
                     /product="putative ubiquitin-protein ligase UBR2"
                     /protein_id="NP_013124.1"
                     /db_xref="GI:6323052"
                     /db_xref="SGD:S000004014"
                     /db_xref="GeneID:850711"
                     /translation="MEDSDLSITNIRDFLTELPKLAKCEYSETTSYLLWKTLNLRLKH
                     SDNDINWRSLVSILNSEAWENEKYRDILNGRKWRTLEFENDHHSVGNMHIGTACTRLC
                     FPSETIYYCFTCSTNPLYEICELCFDKEKHVNHSYVAKVVMRPEGRICHCGDPFAFND
                     PSDAFKCKNELNNIPISNDNSNVTDDENVISLLNYVLDFLIDVTVSYKEEAEAHSSER
                     KASSLMHPNQNSITDDIMEKHECEPLVNDENFVFFDNNWSNTRKEAHMEWAIQIEEEE
                     CNVHYMDLASTITRILNTPVEYAISITKALEDSHDVVTVLQSENFFEIDQIAKEFQKE
                     NIVVHVRKADDIFKRKLTDDLTDWLYSLCFKAATSLQNKYALRISMLDVWYSHFSKMR
                     VSPTNTNPDFSKINLLGGFLISNEDSDESWFKPWSLENIEDERISKILTNYNERLIRA
                     HSPNTVSHFYNFYGSRFQYIIINSINILSKKSKFKMLKIMASLFSLRDESRKFLAAQY
                     IDVYLSVLYDAVASDAKECQVTLMSILGQYTFQDPSIANMTISSGFIERTIRFAFTLM
                     AFNPEDLMSYLPISLYNGFKLPTETIRNRRTIICFKDLCTIMSANTVPEELLSNEAIF
                     NAIIESFSEFSNVLPLKRETKEHVEVENFDFSAFYFFFSSILIMTDGYTRSISLVKDA
                     AFRKQIVLKLLDVAQTREFESLTNSRKAISPDNASTNENDSNKATLSTVRETICNYVA
                     ETINFQVGVNTQYFFNPMSYLFKFVIQWSQCGRYEPIPASLTNYINLFEVFQDKQKAL
                     YISESALSTLVLIGQINVGFWVRNGTPITHQARMYTKYSMREFTYISDIFNVQFSMAM
                     CNPDELMVTYLSRWGLKHWANGVPMYDYPDTETTVAVVNECILLLIQLLTEVRSLVMK
                     SSKEGFERTFKSEIIHALCFDTCSYAQIVNCIPEHITKHPSFDIYLEKYANYTSPVSL
                     TDNGIFVLKEKYKDEIDPYYIGLSSSRRYDVEKNIRLNMANLKKMKYEDTFVPAKKVK
                     DLLKNTLFSGLYSISSVNTFGLFLKNTLDHIIKYDYDNLLPRVVHLIHLCVVNNLNEF
                     MGILWHEYAIVDTEFCHYHSIGSILYYCLLKDNFSESHGKIREIFRYLMETAPHVNVN
                     SYLREQTTSYTPGILWPTKEDKSHKDKEFERKKHLARLRKKKLMKKLAQQQMKFMENN
                     SVDTSDISTPRTTSPSLSPTRINAENSSNTINSCCDDDCVFCKMPKDDDVFVYFSYQE
                     RNICDHGIDFTNPTDVNRINSLFSGKQTKDSAIQENPQDDDGTRLKFTSCEPVLRACG
                     HGSHTKCLSGHMKSIRGIQNQTTKNIPLSYGSGLIYCPVCNSLSNSFLPKTNDIDKRT
                     SSQFFMCIEKRSEAEENLDPMSSICIKAAMILGDLQGKKVTTIEDAYKVVNSVFINTI
                     SNTELRLRSHKKEGKIVNMERISSQCILTLHLVCELKSFIYKKFVNSKTFSSEISRKI
                     WNWNEFLIKGNNVNLLLYMSQNFDNIDGGKTPQPPNLCIYEMFKRRFHQLLLLLARDM
                     MRVNFYKDCRNKIKISSNGSEEPSTSFSYLFNTFKKYVDLFKPDDVRFDFTSLEKIKD
                     FICSLLLESLSIFCRRTFLLFNIQYDDDGDGDNNNNRSNNFMDVKQREIELIFRYFKL
                     PNLTHFLKDFFYNELTQNIERYNDGNDNLRIQQVIYDMVQNINTRAYPSPEHIQLIEL
                     PLNLSKFSLDNDEISNKCDKYEIAVCLLCGQKCHIQKSIALQGYLQGECTDHMRNGCE
                     ITSAYGVFLMTGTNAIYLSYGKRGTFYAAPYLSKYGETNEDYKFGTPVYLNRARYANL
                     ANEIVFGNMIPHIVFRLTDGSADLGGWETM"
     gene            <194452..>195174
                     /gene="SNF7"
                     /locus_tag="YLR025W"
                     /gene_synonym="DID1; RNS4; VPL5; VPS32"
                     /db_xref="GeneID:850712"
     mRNA            <194452..>195174
                     /gene="SNF7"
                     /locus_tag="YLR025W"
                     /gene_synonym="DID1; RNS4; VPL5; VPS32"
                     /product="ESCRT-III subunit protein SNF7"
                     /transcript_id="NM_001181912.1"
                     /db_xref="GI:296146563"
                     /db_xref="GeneID:850712"
     CDS             194452..195174
                     /gene="SNF7"
                     /locus_tag="YLR025W"
                     /gene_synonym="DID1; RNS4; VPL5; VPS32"
                     /note="One of four subunits of the ESCRT-III complex;
                     involved in the sorting of transmembrane proteins into the
                     multivesicular body (MVB) pathway; recruited from the
                     cytoplasm to endosomal membranes; ESCRT-III stands for
                     endosomal sorting complex required for transport III"
                     /codon_start=1
                     /product="ESCRT-III subunit protein SNF7"
                     /protein_id="NP_013125.1"
                     /db_xref="GI:6323053"
                     /db_xref="SGD:S000004015"
                     /db_xref="GeneID:850712"
                     /translation="MWSSLFGWTSSNAKNKESPTKAIVRLREHINLLSKKQSHLRTQI
                     TNQENEARIFLTKGNKVMAKNALKKKKTIEQLLSKVEGTMESMEQQLFSIESANLNLE
                     TMRAMQEGAKAMKTIHSGLDIDKVDETMDEIREQVELGDEISDAISRPLITGANEVDE
                     DELDEELDMLAQENANQETSKIVNNNVNAAPISENKVSLPSVPSNKIKQSENSVKDGE
                     EEEDEEDEDEKALRELQAEMGL"
     gene            complement(<195450..>196472)
                     /gene="SED5"
                     /locus_tag="YLR026C"
                     /db_xref="GeneID:850713"
     mRNA            complement(<195450..>196472)
                     /gene="SED5"
                     /locus_tag="YLR026C"
                     /product="Sed5p"
                     /transcript_id="NM_001181913.1"
                     /db_xref="GI:296146564"
                     /db_xref="GeneID:850713"
     CDS             complement(195450..196472)
                     /gene="SED5"
                     /locus_tag="YLR026C"
                     /note="cis-Golgi t-SNARE syntaxin; required for vesicular
                     transport between the ER and the Golgi complex; binds at
                     least 9 SNARE proteins"
                     /codon_start=1
                     /product="Sed5p"
                     /protein_id="NP_013126.1"
                     /db_xref="GI:6323054"
                     /db_xref="SGD:S000004016"
                     /db_xref="GeneID:850713"
                     /translation="MNIKDRTSEFQQSVLSYKKRNKNFREQQRERLQEKESENFANNT
                     TGNGKSVSEFQKKASGIAHEISSTAQLLSKLAVLAKRKPMFNDNPVEIAELSFLIKRK
                     IYAIEQSLVQLSQLKKTDVNGNTSNQSSKQPSAVQHSKNVVNLLNTQMKNISGSFKDV
                     LEERQRLEMANKDRWQKLTTDTGHAPADDQTQSNHAADLTTYNNSNPFMTSLLDESSE
                     KNNNSSNQGELSFPQNDSQLMLMEEGQLSNNVYLQERNRAVETIESTIQEVGNLFQQL
                     ASMVQEQGEVIQRIDANVDDIDLNISGAQRELLKYFDRIKSNRWLAAKVFFIIFVFFV
                     IWVLVN"
     gene            complement(<196829..>198085)
                     /gene="AAT2"
                     /locus_tag="YLR027C"
                     /gene_synonym="ASP5"
                     /db_xref="GeneID:850714"
     mRNA            complement(<196829..>198085)
                     /gene="AAT2"
                     /locus_tag="YLR027C"
                     /gene_synonym="ASP5"
                     /product="aspartate transaminase AAT2"
                     /transcript_id="NM_001181914.1"
                     /db_xref="GI:296146565"
                     /db_xref="GeneID:850714"
     CDS             complement(196829..198085)
                     /gene="AAT2"
                     /locus_tag="YLR027C"
                     /gene_synonym="ASP5"
                     /EC_number="2.6.1.1"
                     /note="Cytosolic aspartate aminotransferase involved in
                     nitrogen metabolism; localizes to peroxisomes in
                     oleate-grown cells"
                     /codon_start=1
                     /product="aspartate transaminase AAT2"
                     /protein_id="NP_013127.2"
                     /db_xref="GI:37362677"
                     /db_xref="SGD:S000004017"
                     /db_xref="GeneID:850714"
                     /translation="MSATLFNNIELLPPDALFGIKQRYGQDQRATKVDLGIGAYRDDN
                     GKPWVLPSVKAAEKLIHNDSSYNHEYLGITGLPSLTSNAAKIIFGTQSDAFQEDRVIS
                     VQSLSGTGALHISAKFFSKFFPDKLVYLSKPTWANHMAIFENQGLKTATYPYWANETK
                     SLDLNGFLNAIQKAPEGSIFVLHSCAHNPTGLDPTSEQWVQIVDAIASKNHIALFDTA
                     YQGFATGDLDKDAYAVRLGVEKLSTVSPVFVCQSFAKNAGMYGERVGCFHLALTKQAQ
                     NKTIKPAVTSQLAKIIRSEVSNPPAYGAKIVAKLLETPELTEQWHKDMVTMSSRITKM
                     RHALRDHLVKLGTPGNWDHIVNQCGMFSFTGLTPQMVKRLEETHAVYLVASGRASIAG
                     LNQGNVEYVAKAIDEVVRFYTIEAKL"
     gene            198784..199389
                     /locus_tag="snR30"
                     /db_xref="GeneID:9164925"
     ncRNA           198784..199389
                     /locus_tag="snR30"
                     /ncRNA_class="snoRNA"
                     /product="SNR30"
                     /note="H/ACA box small nucleolar RNA (snoRNA); essential
                     gene required for cleavage of 35S primary rRNA transcript
                     to release the precursor to the 18S rRNA"
                     /db_xref="SGD:S000007497"
                     /db_xref="GeneID:9164925"
     gene            complement(<199540..>201315)
                     /gene="ADE16"
                     /locus_tag="YLR028C"
                     /db_xref="GeneID:850715"
     mRNA            complement(<199540..>201315)
                     /gene="ADE16"
                     /locus_tag="YLR028C"
                     /product="bifunctional
                     phosphoribosylaminoimidazolecarboxamide
                     formyltransferase/IMP cyclohydrolase ADE16"
                     /transcript_id="NM_001181915.1"
                     /db_xref="GI:296146566"
                     /db_xref="GeneID:850715"
     CDS             complement(199540..201315)
                     /gene="ADE16"
                     /locus_tag="YLR028C"
                     /EC_number="3.5.4.10"
                     /EC_number="2.1.2.3"
                     /note="Enzyme of 'de novo' purine biosynthesis; contains
                     both 5-aminoimidazole-4-carboxamide ribonucleotide
                     transformylase and inosine monophosphate cyclohydrolase
                     activities; ADE16 has a paralog, ADE17, that arose from
                     the whole genome duplication; ade16 ade17 mutants require
                     adenine and histidine"
                     /codon_start=1
                     /product="bifunctional
                     phosphoribosylaminoimidazolecarboxamide
                     formyltransferase/IMP cyclohydrolase ADE16"
                     /protein_id="NP_013128.1"
                     /db_xref="GI:6323056"
                     /db_xref="SGD:S000004018"
                     /db_xref="GeneID:850715"
                     /translation="MGKYTKTAILSVYDKTGLLDLAKGLVENNVRILASGGTANMVRE
                     AGFPVDDVSSITHAPEMLGGRVKTLHPAVHAGILARNLEGDEKDLKEQHIDKVDFVVC
                     NLYPFKETVAKIGVTVQEAVEEIDIGGVTLLRAAAKNHSRVTILSDPNDYSIFLQDLS
                     KDGEISQDLRNRFALKAFEHTADYDAAISDFFRKQYSEGKAQLPLRYGCNPHQRPAQA
                     YITQQEELPFKVLCGTPGYINLLDALNSWPLVKELSASLNLPAAASFKHVSPAGAAVG
                     LPLSDVERQVYFVNDMEDLSPLACAYARARGADRMSSFGDFIALSNIVDVATAKIISK
                     EVSDGVIAPGYEPEALNILSKKKNGKYCILQIDPNYVPGQMESREVFGVTLQQKRNDA
                     IINQSTFKEIVSKNKALTEQAVIDLTVATLVLKYTQSNSVCYAKNGMVVGLGAGQQSR
                     IHCTRLAGDKTDNWWLRQHPKVLNMKWAKGIKRADKSNAIDLFVTGQRIEGPEKVDYE
                     SKFEEVPEPFTKEERLEWLSKLNNVSLSSDAFFPFPDNVYRAVQSGVKFITAPSGSVM
                     DKVVFQAADSFDIVYVENPIRLFHH"
     gene            complement(<201976..>202590)
                     /gene="RPL15A"
                     /locus_tag="YLR029C"
                     /gene_synonym="RPL10A"
                     /db_xref="GeneID:850716"
     mRNA            complement(<201976..>202590)
                     /gene="RPL15A"
                     /locus_tag="YLR029C"
                     /gene_synonym="RPL10A"
                     /product="ribosomal 60S subunit protein L15A"
                     /transcript_id="NM_001181916.1"
                     /db_xref="GI:296146567"
                     /db_xref="GeneID:850716"
     CDS             complement(201976..202590)
                     /gene="RPL15A"
                     /locus_tag="YLR029C"
                     /gene_synonym="RPL10A"
                     /note="Ribosomal 60S subunit protein L15A; binds to 5.8 S
                     rRNA; homologous to mammalian ribosomal protein L15, no
                     bacterial homolog; RPL15A has a paralog, RPL15B, that
                     arose from the whole genome duplication"
                     /codon_start=1
                     /product="ribosomal 60S subunit protein L15A"
                     /protein_id="NP_013129.1"
                     /db_xref="GI:6323057"
                     /db_xref="SGD:S000004019"
                     /db_xref="GeneID:850716"
                     /translation="MGAYKYLEELQRKKQSDVLRFLQRVRVWEYRQKNVIHRAARPTR
                     PDKARRLGYKAKQGFVIYRVRVRRGNRKRPVPKGATYGKPTNQGVNELKYQRSLRATA
                     EERVGRRAANLRVLNSYWVNQDSTYKYFEVILVDPQHKAIRRDARYNWICDPVHKHRE
                     ARGLTATGKKSRGINKGHKFNNTKAGRRKTWKRQNTLSLWRYRK"
     gene            <203290..>204081
                     /locus_tag="YLR030W"
                     /db_xref="GeneID:850717"
     mRNA            <203290..>204081
                     /locus_tag="YLR030W"
                     /product="hypothetical protein"
                     /transcript_id="NM_001181917.1"
                     /db_xref="GI:296146568"
                     /db_xref="GeneID:850717"
     CDS             203290..204081
                     /locus_tag="YLR030W"
                     /note="hypothetical protein; S288C contains an in-frame
                     stop codon between ORFs YLR030W and YLR031W"
                     /codon_start=1
                     /product="hypothetical protein"
                     /protein_id="NP_013130.1"
                     /db_xref="GI:6323058"
                     /db_xref="SGD:S000004020"
                     /db_xref="GeneID:850717"
                     /translation="MEGEQIMEYVQETPIIPKRIIHYSIPKQMITKPAPHVEMTLVAN
                     TFRDMDLPQHPVIHDCWQNKEYSTQRYSGNVAQQRLSFEEHPNEECQNSVGLIKRVST
                     FFKKRPLSRKNSIKSIGDVKSEARNRGEGLLGEVDNLNEQNVRENLTSEHEKSPEGDS
                     KRYGLFSFEETPPIQVLEQGNINSELSSFKNTSLAENKRSSDSFVSLKPGEDEHSPLE
                     ISTCGNLTEREDLQSGEERFDSAAQNIKVASMKEKKKIFKGNKTD"
     gene            <204225..>204785
                     /locus_tag="YLR031W"
                     /db_xref="GeneID:850718"
     mRNA            <204225..>204785
                     /locus_tag="YLR031W"
                     /product="hypothetical protein"
                     /transcript_id="NM_001181918.1"
                     /db_xref="GI:296146569"
                     /db_xref="GeneID:850718"
     CDS             204225..204785
                     /locus_tag="YLR031W"
                     /note="hypothetical protein; S288C contains an in-frame
                     stop codon between ORFs YLR030W and YLR031W; YLR031W has a
                     paralog, YMR124W, that arose from the whole genome
                     duplication"
                     /codon_start=1
                     /product="hypothetical protein"
                     /protein_id="NP_013131.1"
                     /db_xref="GI:6323059"
                     /db_xref="SGD:S000004021"
                     /db_xref="GeneID:850718"
                     /translation="MPVLNTRTSYPNIDFHGTKVSDVLDAFEFEKHDDPLRDKWNTLQ
                     FLEKSFESKFESASELIQGGELAAIKERNFQLAKLNNLCFRVRESIKRRQDLEKKLRT
                     LSQDTDNELLFLMLENERRKKSSVIIEFLSEIIREKSKRLTAEEQGFVNQNEVKPLIL
                     DLSARINRLNSILETKNTCIRRLSNQ"
     gene            <204991..>208500
                     /gene="RAD5"
                     /locus_tag="YLR032W"
                     /gene_synonym="REV2; SNM2"
                     /db_xref="GeneID:850719"
     mRNA            <204991..>208500
                     /gene="RAD5"
                     /locus_tag="YLR032W"
                     /gene_synonym="REV2; SNM2"
                     /product="DNA helicase RAD5"
                     /transcript_id="NM_001181919.1"
                     /db_xref="GI:296146570"
                     /db_xref="GeneID:850719"
     CDS             204991..208500
                     /gene="RAD5"
                     /locus_tag="YLR032W"
                     /gene_synonym="REV2; SNM2"
                     /EC_number="3.6.4.-"
                     /note="DNA helicase/Ubiquitin ligase; involved in
                     error-free branch of DNA damage tolerance (DDT) pathway;
                     proposed to promote replication fork regression during
                     postreplication repair by template switching; stimulates
                     synthesis of free and PCNA-bound polyubiquitin chains by
                     Ubc13p-Mms2p; required for error-prone translesion
                     synthesis; forms nuclear foci upon DNA replication stress;
                     associates with native telomeres, cooperates with
                     homologous recombination in senescent cells"
                     /codon_start=1
                     /product="DNA helicase RAD5"
                     /protein_id="NP_013132.1"
                     /db_xref="GI:6323060"
                     /db_xref="SGD:S000004022"
                     /db_xref="GeneID:850719"
                     /translation="MSHIEQEERKRFFNDDLDTSETSLNFKSENKESFLFANSHNDDD
                     DDVVVSVSDTTEGEGDRSIVPVRREIEEEGQNQFITELLRIIPEMPKDLVMELNEKFG
                     SQEEGLSLALSHYFDHNSGTSISKIPSSPNQLNTLSDTSNSTLSPSSFHPKRRRIYGF
                     RNQTRLEDKVTWKRFIGALQVTGMATRPTVRPLKYGSQMKLKRSSEEISATKVYDSRG
                     RKKASMASLVRIFDIQYDREIGRVSEDIAQILYPLLSSHEISFEVTLIFCDNKRLSIG
                     DSFILQLDCFLTSLIFEERNDGESLMKRRRTEGGNKREKDNGNFGRTLTETDEELESR
                     SKRLALLKLFDKLRLKPILDEQKALEKHKIELNSDPEIIDLDNDEICSNQVTEVHNNL
                     RDTQHEEETMNLNQLKTFYKAAQSSESLKSLPETEPSRDVFKLELRNYQKQGLTWMLR
                     REQEFAKAASDGEASETGANMINPLWKQFKWPNDMSWAAQNLQQDHVNVEDGIFFYAN
                     LHSGEFSLAKPILKTMIKGGILSDEMGLGKTVAAYSLVLSCPHDSDVVDKKLFDIENT
                     AVSDNLPSTWQDNKKPYASKTTLIVVPMSLLTQWSNEFTKANNSPDMYHEVYYGGNVS
                     SLKTLLTKTKTPPTVVLTTYGIVQNEWTKHSKGRMTDEDVNISSGLFSVNFYRIIIDE
                     GHNIRNRTTVTSKAVMALQGKCKWVLTGTPIINRLDDLYSLVKFLELDPWRQINYWKT
                     FVSTPFESKNYKQAFDVVNAILEPVLLRRTKQMKDKDGKPLVELPPKEVVIKRLPFSK
                     SQDLLYKFLLDKAEVSVKSGIARGDLLKKYSTILVHILRLRQVCCHPGLIGSQDENDE
                     DLSKNNKLVTEQTVELDSLMRVVSERFDNSFSKEELDAMIQRLKVKYPDNKSFQSLEC
                     SICTTEPMDLDKALFTECGHSFCEKCLFEYIEFQNSKNLGLKCPNCRNQIDACRLLAL
                     VQTNSNSKNLEFKPYSPASKSSKITALLKELQLLQDSSAGEQVVIFSQFSTYLDILEK
                     ELTHTFSKDVAKIYKFDGRLSLKERTSVLADFAVKDYSRQKILLLSLKAGGVGLNLTC
                     ASHAYMMDPWWSPSMEDQAIDRLHRIGQTNSVKVMRFIIQDSIEEKMLRIQEKKRTIG
                     EAMDTDEDERRKRRIEEIQMLFE"
     gene            <208761..>210269
                     /gene="RSC58"
                     /locus_tag="YLR033W"
                     /db_xref="GeneID:850720"
     mRNA            <208761..>210269
                     /gene="RSC58"
                     /locus_tag="YLR033W"
                     /product="Rsc58p"
                     /transcript_id="NM_001181920.1"
                     /db_xref="GI:296146571"
                     /db_xref="GeneID:850720"
     CDS             208761..210269
                     /gene="RSC58"
                     /locus_tag="YLR033W"
                     /note="Component of the RSC chromatin remodeling complex;
                     RSC functions in transcriptional regulation and
                     elongation, chromosome stability, and establishing sister
                     chromatid cohesion; involved in telomere maintenance"
                     /codon_start=1
                     /product="Rsc58p"
                     /protein_id="NP_013133.1"
                     /db_xref="GI:6323061"
                     /db_xref="SGD:S000004023"
                     /db_xref="GeneID:850720"
                     /translation="MTESVGGNKLVDFLVNVQSILNAASVKCHVVDESFPAKFFEKNP
                     DKIYESYCKFIKNRSNSEGLIRNEDKLVLTTINKRFENGEYEPIQGGFYKLYHDIKLV
                     CTILIHFYPQGTRNYQLVDKFYKFSSELLLRECCRIGIALTQTNNIKSRSGKLLSGNE
                     MDEYDDDDATELDKIISYDFIKISMNYTVPISQTYQIRTKDMDLFSSIISKSNLDKRP
                     HELPNTNFKINNVLPQTDIENEAPRLGFVGANTSNIPDPTLPPTEMMTRFLHPNWYAL
                     PTTVWLKYGNYNSWAPSFNENGTVVDSTTRGLIWLERIGYMDLYEKNEKKVKQEELLN
                     TNEEGINRKQNDENNKNVDGKSNGVQDDGGDNDNDATIASANSESTENKEQFIIKLQN
                     LYNWTPSNYIGDDEIENFRNGTPDKLVSDSLLKLKRLRKERILNKVLKPTTEERELYF
                     KVKRILKEVILAKKVSKVPINNVRAFPVLQTNYNGSIPVVRAQPGRKRKHKK"
     gene            complement(<210512..>211933)
                     /gene="SMF3"
                     /locus_tag="YLR034C"
                     /db_xref="GeneID:850721"
     mRNA            complement(<210512..>211933)
                     /gene="SMF3"
                     /locus_tag="YLR034C"
                     /product="putative divalent metal ion transporter SMF3"
                     /transcript_id="NM_001181921.2"
                     /db_xref="GI:330443671"
                     /db_xref="GeneID:850721"
     CDS             complement(210512..211933)
                     /gene="SMF3"
                     /locus_tag="YLR034C"
                     /note="Putative divalent metal ion transporter involved in
                     iron homeostasis; transcriptionally regulated by metal
                     ions; member of the Nramp family of metal transport
                     proteins; protein abundance increases in response to DNA
                     replication stress"
                     /codon_start=1
                     /product="putative divalent metal ion transporter SMF3"
                     /protein_id="NP_013134.1"
                     /db_xref="GI:6323062"
                     /db_xref="SGD:S000004024"
                     /db_xref="GeneID:850721"
                     /translation="MRSYMQILQKFAKFIGPGILVSVAYMDPGNYATSVSGGAQYKYT
                     LLFSIFISNIFAVLLQCLCVKLGTITGYDLAENCRHNLPKKLNYTLYLFAEVAIIATD
                     LAEVVGTAIALQILFKIPLTWGVLLTVLDVLVILMFYTPNGQSLKKVRVFEFGVGILV
                     IGTCICFVLELFKVSIPDKAELFKGFLPSNIIFKEQQALYISLGILGATVMPHSLYLG
                     SSIVKPRLHDYDLKKYGKVNARPSLSAIKYTLNYAYAELIISLFLIATFVNSAILIVA
                     GATLSGQPEAEDADLLSIYKLLVHYISPAAGLIFALAMLCSGQSAGIICTLAGQIVSE
                     GFLQWSLPPWATRLCTRLIAIVPCLFVTLTMGEKGISDILNFSQVVLSLILPIVSAPL
                     IYFTANRKLMVVHDENGVVRAPADVNAIADETTPLNSKHSKIVDFTNSRLLTYTSVFV
                     WALIGSLNCYLVISYLLGADIHF"
     gene            complement(<212369..>214456)
                     /gene="MLH2"
                     /locus_tag="YLR035C"
                     /db_xref="GeneID:850722"
     mRNA            complement(<212369..>214456)
                     /gene="MLH2"
                     /locus_tag="YLR035C"
                     /product="mismatch repair protein MLH2"
                     /transcript_id="NM_001181922.1"
                     /db_xref="GI:296146573"
                     /db_xref="GeneID:850722"
     CDS             complement(212369..214456)
                     /gene="MLH2"
                     /locus_tag="YLR035C"
                     /note="Protein involved in mismatch repair and meiotic
                     recombination; only certain frameshift intermediates are
                     mismatch repair substrates; forms a complex with Mlh1p"
                     /codon_start=1
                     /product="mismatch repair protein MLH2"
                     /protein_id="NP_013135.1"
                     /db_xref="GI:6323063"
                     /db_xref="SGD:S000004025"
                     /db_xref="GeneID:850722"
                     /translation="MTIHQLSPESQWKIVSSSFIYGPVAAVRELLDNSIDSGAKKVFI
                     DVDSTTGGCEYISVKDDGSGVDIIDRPSMCLEYTTSKMSSLGDISILTTLGFRGEALF
                     LLSNLCNQKGSMQVETKTADDVIGEKWLVDSKGGITNGKRYKVSCPVGTTVILRKLLG
                     GLRARYLEISSRPRKTFDELIYLINHYSLIHRNIRFYFSLVSLQKNGAIERKQMQETL
                     DPKISRARSLSLLARLKKPVPLNFIVEENFVIDEKINLDLILPRMVPESDVINIKRRF
                     KFLSVNERALSLNLETGKTISKLLSSIYRDFSLLDPMVWFINLNCDTKLLDVNIEPEK
                     NDVMIKSFEVIFKKIENKLKLLLEERIGIETNMLGDKHVQPSINEKTSPALVIPTPDA
                     ENEISKGCGAVSGKDKTDIPQKNSDLIVPTFYDEANLENTTIVAATPSPTKFSEDKAL
                     DEQTQLTISSYRSSSSGSMASEDSTNWRHNFQQELSENSEVAGAGSSTLPSSLTYNYI
                     ETIPENEDLELSKDASISNPFMITKIRNVNKKLSENLLEAKRTSCGDANKRGMPNERQ
                     LSNTEKKELIKLQQTYGKRNNTVDMTIPRNSKKKVTDNYIKKASCMHKTRPKLMHFSE
                     YTNNYVYTLKNEKIVKHDSDNFAKETLWLRSRDDATSPSSSLLQALRAHVKKPGHIEA
                     TTNEWCLFTPDSP"
     gene            complement(214883..214955)
                     /locus_tag="tA(UGC)L"
                     /db_xref="GeneID:850723"
     tRNA            complement(214883..214955)
                     /locus_tag="tA(UGC)L"
                     /product="tRNA-Ala"
                     /note="Alanine tRNA (tRNA-Ala), predicted by tRNAscan-SE
                     analysis; one of 5 nuclear tRNA genes containing the
                     tDNA-anticodon TGC (mature tRNA may be UGC or may contain
                     modified bases), decodes GCA and probably GCG codons into
                     alanine, one of 16 nuclear tRNAs for alanine"
                     /db_xref="SGD:S000006524"
                     /db_xref="GeneID:850723"
     LTR             complement(215080..215417)
                     /note="Ty1 LTR"
                     /db_xref="SGD:S000007065"
     gene            complement(<215440..>218907)
                     /locus_tag="YLR035C-A"
                     /db_xref="GeneID:850724"
     mRNA            complement(<215440..>218907)
                     /locus_tag="YLR035C-A"
                     /product="gag-pol fusion protein"
                     /transcript_id="NM_001184318.1"
                     /db_xref="GI:296146574"
                     /db_xref="GeneID:850724"
     CDS             complement(215440..218907)
                     /locus_tag="YLR035C-A"
                     /EC_number="3.1.26.4"
                     /EC_number="2.7.7.7"
                     /EC_number="2.7.7.49"
                     /EC_number="3.4.23.-"
                     /note="Retrotransposon TYA Gag and TYB Pol genes;
                     polyprotein is processed to make a nucleocapsid-like
                     protein (Gag), reverse transcriptase (RT), protease (PR),
                     and integrase (IN); YLR035C-A is part of a mutant
                     retrotransposon"
                     /codon_start=1
                     /product="gag-pol fusion protein"
                     /protein_id="NP_013136.1"
                     /db_xref="GI:6323064"
                     /db_xref="SGD:S000007225"
                     /db_xref="GeneID:850724"
                     /translation="MLAHANAQTIRYSLKNNTITYFNESDVDWSSAIDYQCPDCLIGK
                     STKHRHIKGSRLKYQNSYEPFQYLHTDIFGPVHNLPKSAPSYFISFTDETTKFRWVYP
                     LHDRREDSILDVFTTILAFIKNQFQASVLVIQMDRGSEYTNRTLHKFLEKNGITPCYT
                     TTADSRAHGVAERLNRTLLDDCRTQLQCSGLPNHLWFSAIEFSTIVRNSLASPKSKKS
                     ARQHAGLAGLDISTLLPFGQPVIVNDHNPNSKIHPRGIPGYALHPSRNSYGYIIYLPS
                     LKKTVDTTNYVILQGKESRLDQFNYDALTFDEDLNRLTASYQSFIASNEIQQSDDLNI
                     ESDHDFQSDIELHPEQPRNVLSKAVSPTDSTPPSTHTEDSKRVSKTNIRAPREVDPNI
                     SESNILPSKKRSSTPQISDIESTGSGGMHRLDVPLLAPMSQSNTHESSHASKSKDFRH
                     SDSYSDNETNHTNVPISSTGGTNNKTVPQTSEQETEKRIIHRSPSIDTSSSESNSLHH
                     VVPIKTSDTCPKENTEESIIADLPLPDLPPEPPTELSDSFKELPPINSHQTNSSLGGI
                     GDSNAYTTINSKKRSLEDNETEIKVSRDTWNTKNMRSLEPPRSKKRIHLIAAVKAVKS
                     IKPIRTTLRYDEAITYNKDIKEKEKYIQAYHKEVNQLLKMKTWDTDRYYDRKEIDPKR
                     VINSMFIFNRKRGGTHKARFVARGDIQHPDTYDPGMQSNTVHHYALMTSLSLASDNNY
                     YITQLDISSAYLYADIKEELYIRPPPHLGMNDKLIRLKKSLYGLKQSGANWYETIKSY
                     LIKQCGMEEVRGWSCVFKNSQVTICLFVDDMILFSKDLNANKKIITTLKKQYDTKIIN
                     LGESDNEIQYDILGLEIKYQRGKYMKLGMENSLTEKIPKLNVPLNPKGRKLSAPGQPG
                     LYIDQQELELEEDDYKMKVHEMQKLIGLASYVGYKFRFDLLYYINTLAQHILFPSKQV
                     LDMTYELIQFIWNTRDKQLIWHKSKPVKPTNKLVVISDASYGNQPYYKSQIGNIYLLN
                     GKVIGGKSTKASLTCTSTTEAEIHAISESVPLLNNLSHLVQELNKKPITKGLLTDSKS
                     TISIIISNNEEKFRNRFFGTKAMRLRDEVSGNHLHVCYIETKKNIADVMTKPLPIKTF
                     KLLTNKWIH"
     LTR             complement(220668..221005)
                     /note="Ty1 LTR"
                     /db_xref="SGD:S000007066"
     LTR             221006..221266
                     /note="Ty1 LTR"
                     /db_xref="SGD:S000007083"
     gene            complement(<221521..>222132)
                     /locus_tag="YLR036C"
                     /db_xref="GeneID:850725"
     mRNA            complement(<221521..>222132)
                     /locus_tag="YLR036C"
                     /product="hypothetical protein"
                     /transcript_id="NM_001181923.1"
                     /db_xref="GI:296146575"
                     /db_xref="GeneID:850725"
     CDS             complement(221521..222132)
                     /locus_tag="YLR036C"
                     /note="Putative protein predicted to have transmembrane
                     domains; interacts with HSP90 by yeast two-hybrid
                     analysis; YLR036C is not an essential protein"
                     /codon_start=1
                     /product="hypothetical protein"
                     /protein_id="NP_013137.1"
                     /db_xref="GI:6323065"
                     /db_xref="SGD:S000004026"
                     /db_xref="GeneID:850725"
                     /translation="MKEAELSATESQDEIPKSNSLLIIEKLTKAVCSLYFINCFMVPS
                     VDNLIEKYPKAIIIKIIDMILGAVTISLVIIVFFLYRKNGHFKNENKTKPKRCSKVVC
                     PSCAARKKYPKWFQLKYLLLVSMTAFSFYFCTKIRFFFKTDQTINLHRLSQLFRLQLG
                     WICTTALLFYFYDALILHSGFIEGYRCVNGKGAMSEGKTGQLN"
     gene            complement(<222685..>223059)
                     /gene="PAU23"
                     /locus_tag="YLR037C"
                     /gene_synonym="DAN2"
                     /db_xref="GeneID:850726"
     mRNA            complement(<222685..>223059)
                     /gene="PAU23"
                     /locus_tag="YLR037C"
                     /gene_synonym="DAN2"
                     /product="Pau23p"
                     /transcript_id="NM_001181924.1"
                     /db_xref="GI:296146576"
                     /db_xref="GeneID:850726"
     CDS             complement(222685..223059)
                     /gene="PAU23"
                     /locus_tag="YLR037C"
                     /gene_synonym="DAN2"
                     /note="Cell wall mannoprotein; has similarity to Tir1p,
                     Tir2p, Tir3p, and Tir4p; member of the seripauperin
                     multigene family encoded mainly in subtelomeric regions;
                     expressed under anaerobic conditions, completely repressed
                     during aerobic growth"
                     /codon_start=1
                     /product="Pau23p"
                     /protein_id="NP_013138.1"
                     /db_xref="GI:6323066"
                     /db_xref="SGD:S000004027"
                     /db_xref="GeneID:850726"
                     /translation="MVKLTSIVAGVAAIAAGVAAAPATTTLSPSDERVNLVELGVYVS
                     DIRAHLAEYYMFQAAHPTETYPVEIAEAVFNYGDFTTMLTGIPADQVTRVITGVPWYS
                     TRLRPAISSALSKDGIYTAVPN"
     gene            complement(<224921..>225172)
                     /gene="COX12"
                     /locus_tag="YLR038C"
                     /db_xref="GeneID:850727"
     mRNA            complement(<224921..>225172)
                     /gene="COX12"
                     /locus_tag="YLR038C"
                     /product="cytochrome c oxidase subunit VIb"
                     /transcript_id="NM_001181925.1"
                     /db_xref="GI:296146577"
                     /db_xref="GeneID:850727"
     CDS             complement(224921..225172)
                     /gene="COX12"
                     /locus_tag="YLR038C"
                     /EC_number="1.9.3.1"
                     /note="Subunit VIb of cytochrome c oxidase; cytochrome c
                     oxidase is also known as respiratory Complex IV and is the
                     terminal member of the mitochondrial inner membrane
                     electron transport chain; required for assembly of
                     cytochrome c oxidase but not required for activity after
                     assembly; phosphorylated; easily released from the
                     intermembrane space, suggesting a loose association with
                     Complex IV"
                     /codon_start=1
                     /product="cytochrome c oxidase subunit VIb"
                     /protein_id="NP_013139.1"
                     /db_xref="GI:6323067"
                     /db_xref="SGD:S000004028"
                     /db_xref="GeneID:850727"
                     /translation="MADQENSPLHTVGFDARFPQQNQTKHCWQSYVDYHKCVNMKGED
                     FAPCKVFWKTYNALCPLDWIEKWDDQREKGIFAGDINSD"
     gene            complement(<225426..>228596)
                     /gene="RIC1"
                     /locus_tag="YLR039C"
                     /db_xref="GeneID:850728"
     mRNA            complement(<225426..>228596)
                     /gene="RIC1"
                     /locus_tag="YLR039C"
                     /product="Ric1p"
                     /transcript_id="NM_001181926.1"
                     /db_xref="GI:296146578"
                     /db_xref="GeneID:850728"
     CDS             complement(225426..228596)
                     /gene="RIC1"
                     /locus_tag="YLR039C"
                     /note="Protein involved in retrograde transport to the
                     cis-Golgi network; forms heterodimer with Rgp1p that acts
                     as a GTP exchange factor for Ypt6p; involved in
                     transcription of rRNA and ribosomal protein genes"
                     /codon_start=1
                     /product="Ric1p"
                     /protein_id="NP_013140.1"
                     /db_xref="GI:6323068"
                     /db_xref="SGD:S000004029"
                     /db_xref="GeneID:850728"
                     /translation="MFIKQSEKNTPKCLYKKKGKVRVLLTGSCKKLNTWKMHLWPVSP
                     PQLLRIPPRNAELGEGTKIDDCNILQSMTLPQANVLIMLTPTRVLIYNFKPMALVASH
                     ERTMASLKEFGDNRSMKRSAPYNDIIEGLISKKDSQYLLWHQGKLIFYVMTDKNFLLT
                     YQILKNCTNEIIFKEYGIPVIEPLLMSEEEANSAEYDYNNDDDTLTVFDKNSSSRIIQ
                     NGFGITKEKGFLHFLSNQENIDELPVKKLELRLKVVLKFDYEIIDMIGIKTFSKVGDG
                     RYEEVLIVLFPHGLQILTISDFKVSKSSLVEVKKGSKTIVCNKQLMVLSHDSVEKQTI
                     VSIIDIEKQAVEAIPLTDTPDELLTCLEVNGYLVVVYKEKIICFDTRIKKVSHSWKPP
                     FVIKLCDKINDKILLLVSEDSVNIHFYTEFGNLLFATYFDEDDYNGDNNNDNSKDKNE
                     KKAAEYKISDFVCLDKSLITVSHSGKYQVWKLWEEIKQTQFDFRNPKCYVLTNTNNDV
                     IIYSPVTSSSINNDNLQVIKLPTKTFNNHIAFVKINSSLRLFATYVSNKNILLIHNLE
                     TNMWSSFADQNVLDLHWLGDNYLVCHMKNDDGSTNLKCLQIPLQEANPDVELSDYVMW
                     EYNVPENTIVFSLHVNTLSRYKLLKMKSKNHNASEKQPDALLKTAEIILVTDTQTIVF
                     DVISTVHPCGLNIIKKFYQYLKINIPIDVLPNKIEWIINMKEGLLFFADRKFIKLGKV
                     DGGGWQTLTLLDNIEKIIDVIRDEIFVVQGHNYVVYSLEDLWDDKKPLVSIPIEEDLY
                     PISTTPETATTHTLHCIFNARFSKLVVKHQIYLDQLILAKLEDNTDLEDISHNYRFLK
                     PYKFALEKILSTKILRSDSLDDILKLIKMYDNTDPEHNISPPTHSGMLEIISNCLRKI
                     ETKYWNHLFTNLKMTPRDLLALCIEENEAKMLGVLLLVFLNYDEKDLGDDLHFKKSDL
                     GTEESKALNDNSTKKSEKSVTNLLKDEELMLKVLELLVTSAANATDPIKATDSWDMCF
                     QLIRLLKELDRENNTQLVQKALERFK"
     gene            complement(<228908..>229582)
                     /gene="AFB1"
                     /locus_tag="YLR040C"
                     /db_xref="GeneID:850730"
     mRNA            complement(<228908..>229582)
                     /gene="AFB1"
                     /locus_tag="YLR040C"
                     /product="Afb1p"
                     /transcript_id="NM_001181927.1"
                     /db_xref="GI:296146579"
                     /db_xref="GeneID:850730"
     CDS             complement(228908..229582)
                     /gene="AFB1"
                     /locus_tag="YLR040C"
                     /note="MATalpha-specific a-factor blocker; contributes to
                     mating efficiency under certain conditions; localizes to
                     the cell wall; predicted to be a GPI-attached protein;
                     upregulated by Mcm1p-Alpha1p transcription factor;
                     partially overlaps the dubious ORF YLR041W"
                     /codon_start=1
                     /product="Afb1p"
                     /protein_id="NP_013141.1"
                     /db_xref="GI:6323070"
                     /db_xref="SGD:S000004030"
                     /db_xref="GeneID:850730"
                     /translation="MIFAPSFSLIKNILLVSFLISHSFAAKTLTSSSNDDTLARSAAA
                     DADMAFFMEFLNDFDTAFPQYTSYMMQNHLTLPQPVADYYYHMVDLASTADLQSDIAQ
                     SFPFTQFQTFITAFPWYTSLLNKASATTIYLPQHFITGETEATMTNSSYASQKNSVSN
                     SVPFSTANAGQSMISMANEENSTTALISASNSSSTSRTSQSQNGAHAKSLYFPMALFG
                     IFAVAL"
     gene            complement(<229966..>230451)
                     /locus_tag="YLR042C"
                     /db_xref="GeneID:850731"
     mRNA            complement(<229966..>230451)
                     /locus_tag="YLR042C"
                     /product="hypothetical protein"
                     /transcript_id="NM_001181929.1"
                     /db_xref="GI:296146580"
                     /db_xref="GeneID:850731"
     CDS             complement(229966..230451)
                     /locus_tag="YLR042C"
                     /note="Cell wall hypothetical protein; localizes to the
                     cytoplasm; deletion improves xylose fermentation in
                     industrially engineered strains; YLL042C is not an
                     essential gene"
                     /codon_start=1
                     /product="hypothetical protein"
                     /protein_id="NP_013143.1"
                     /db_xref="GI:6323071"
                     /db_xref="SGD:S000004032"
                     /db_xref="GeneID:850731"
                     /translation="MKISQFGSLAFAPIVLLQLFIVQAQLLTDSNAQDLNTALGQKVQ
                     YTFLDTGNSNDQLLHLPSTTSSSIITGSLAAANFTGSSSSSSIPKVTSSVITSINYQS
                     SNSTVVTQFTPLPSSSRNETKSSQTTNTISSSTSTGGVGSVKPCLYFVLMLETIAYLF
                     S"
     rep_origin      231179..231421
                     /note="ARS1211;
                     Autonomously Replicating Sequence"
                     /db_xref="SGD:S000118471"
     gene            complement(<231702..>232013)
                     /gene="TRX1"
                     /locus_tag="YLR043C"
                     /gene_synonym="LMA1"
                     /db_xref="GeneID:850732"
     mRNA            complement(<231702..>232013)
                     /gene="TRX1"
                     /locus_tag="YLR043C"
                     /gene_synonym="LMA1"
                     /product="thioredoxin TRX1"
                     /transcript_id="NM_001181930.1"
                     /db_xref="GI:296146581"
                     /db_xref="GeneID:850732"
     CDS             complement(231702..232013)
                     /gene="TRX1"
                     /locus_tag="YLR043C"
                     /gene_synonym="LMA1"
                     /note="Cytoplasmic thioredoxin isoenzyme; part of
                     thioredoxin system which protects cells against oxidative
                     and reductive stress; forms LMA1 complex with Pbi2p; acts
                     as a cofactor for Tsa1p; required for ER-Golgi transport
                     and vacuole inheritance; with Trx2p, facilitates
                     mitochondrial import of small Tims Tim9p, Tim10p, Tim13p
                     by maintaining them in reduced form; abundance increases
                     iunder DNA replication stress; TRX1 has a paralog, TRX2,
                     that arose from the whole genome duplication"
                     /codon_start=1
                     /product="thioredoxin TRX1"
                     /protein_id="NP_013144.1"
                     /db_xref="GI:6323072"
                     /db_xref="SGD:S000004033"
                     /db_xref="GeneID:850732"
                     /translation="MVTQFKTASEFDSAIAQDKLVVVDFYATWCGPCKMIAPMIEKFS
                     EQYPQADFYKLDVDELGDVAQKNEVSAMPTLLLFKNGKEVAKVVGANPAAIKQAIAAN
                     A"
     gene            complement(<232390..>234081)
                     /gene="PDC1"
                     /locus_tag="YLR044C"
                     /db_xref="GeneID:850733"
     mRNA            complement(<232390..>234081)
                     /gene="PDC1"
                     /locus_tag="YLR044C"
                     /product="indolepyruvate decarboxylase 1"
                     /transcript_id="NM_001181931.1"
                     /db_xref="GI:296146582"
                     /db_xref="GeneID:850733"
     CDS             complement(232390..234081)
                     /gene="PDC1"
                     /locus_tag="YLR044C"
                     /EC_number="4.1.1.-"
                     /EC_number="4.1.1.74"
                     /EC_number="4.1.1.72"
                     /EC_number="4.1.1.1"
                     /note="Major of three pyruvate decarboxylase isozymes; key
                     enzyme in alcoholic fermentation; decarboxylates pyruvate
                     to acetaldehyde; involved in amino acid catabolism;
                     subject to glucose-, ethanol-, and autoregulation;
                     activated by phosphorylation in response to glucose
                     levels; N-terminally propionylated in vivo"
                     /codon_start=1
                     /product="indolepyruvate decarboxylase 1"
                     /protein_id="NP_013145.1"
                     /db_xref="GI:6323073"
                     /db_xref="SGD:S000004034"
                     /db_xref="GeneID:850733"
                     /translation="MSEITLGKYLFERLKQVNVNTVFGLPGDFNLSLLDKIYEVEGMR
                     WAGNANELNAAYAADGYARIKGMSCIITTFGVGELSALNGIAGSYAEHVGVLHVVGVP
                     SISAQAKQLLLHHTLGNGDFTVFHRMSANISETTAMITDIATAPAEIDRCIRTTYVTQ
                     RPVYLGLPANLVDLNVPAKLLQTPIDMSLKPNDAESEKEVIDTILALVKDAKNPVILA
                     DACCSRHDVKAETKKLIDLTQFPAFVTPMGKGSIDEQHPRYGGVYVGTLSKPEVKEAV
                     ESADLILSVGALLSDFNTGSFSYSYKTKNIVEFHSDHMKIRNATFPGVQMKFVLQKLL
                     TTIADAAKGYKPVAVPARTPANAAVPASTPLKQEWMWNQLGNFLQEGDVVIAETGTSA
                     FGINQTTFPNNTYGISQVLWGSIGFTTGATLGAAFAAEEIDPKKRVILFIGDGSLQLT
                     VQEISTMIRWGLKPYLFVLNNDGYTIEKLIHGPKAQYNEIQGWDHLSLLPTFGAKDYE
                     THRVATTGEWDKLTQDKSFNDNSKIRMIEIMLPVFDAPQNLVEQAKLTAATNAKQ"
     gene            complement(<235037..>237703)
                     /gene="STU2"
                     /locus_tag="YLR045C"
                     /db_xref="GeneID:850734"
     mRNA            complement(<235037..>237703)
                     /gene="STU2"
                     /locus_tag="YLR045C"
                     /product="Stu2p"
                     /transcript_id="NM_001181932.1"
                     /db_xref="GI:296146583"
                     /db_xref="GeneID:850734"
     CDS             complement(235037..237703)
                     /gene="STU2"
                     /locus_tag="YLR045C"
                     /note="Microtubule-associated protein (MAP) of the
                     XMAP215/Dis1 family; regulates microtubule dynamics during
                     spindle orientation and metaphase chromosome alignment;
                     interacts with spindle pole body component Spc72p"
                     /codon_start=1
                     /product="Stu2p"
                     /protein_id="NP_013146.1"
                     /db_xref="GI:6323074"
                     /db_xref="SGD:S000004035"
                     /db_xref="GeneID:850734"
                     /translation="MSGEEEVDYTTLPLEERLTYKLWKARLEAYKELNQLFRNSVGDI
                     SRDDNIQIYWRDPTLFAQYITDSNVVAQEQAIVALNSLIDAFASSSLKNAHNITLIST
                     WTPLLVEKGLTSSRATTKTQSMSCILSLCGLDTSITQSVELVIPFFEKKLPKLIAAAA
                     NCVYELMAAFGLTNVNVQTFLPELLKHVPQLAGHGDRNVRSQTMNLIVEIYKVTGNNS
                     DLLEEILFKKLKPIQVKDLHKLFAKVGDEPSSSKMLFEWEKRELEKKRSQEEEARKRK
                     SILSNDEGEYQIDKDGDTLMGMETDMPPSKQQSGVQIDTFSMLPEETILDKLPKDFQE
                     RITSSKWKDRVEALEEFWDSVLSQTKKLKSTSQNYSNLLGIYGHIIQKDANIQAVALA
                     AQSVELICDKLKTPGFSKDYVSLVFTPLLDRTKEKKPSVIEAIRKALLTICKYYDPLA
                     SSGRNEDMLKDILEHMKHKTPQIRMECTQLFNASMKEEKDGYSTLQRYLKDEVVPIVI
                     QIVNDTQPAIRTIGFESFAILIKIFGMNTFVKTLEHLDNLKRKKIEETVKTLPNFSIA
                     SGSTHSTIETNKQTGPMENKFLLKKSSVLPSKRVASSPLRNDNKSKVNPIGSVASASK
                     PSMVAANNKSRVLLTSKSLATPKNVVANSTDKNEKLIEEYKYRLQKLQNDEMIWTKER
                     QSLLEKMNNTENYKIEMIKENEMLREQLKEAQSKLNEKNIQLRSKEIDVNKLSDRVLS
                     LENELRNMEIELDRNKKRNDTNLQSMGTISSYSIPSSTVSSNYGVKSLSSALPFKEEE
                     DVRRKEDVNYERRSSESIGDLPHRVNSLNIRPYRKNGTGVSSVSDDLDIDFNDSFASE
                     ESYKRAAAVTSTLKARIEKMKAKSRREGTTRT"
     gene            complement(<238001..>238813)
                     /locus_tag="YLR046C"
                     /db_xref="GeneID:850735"
     mRNA            complement(<238001..>238813)
                     /locus_tag="YLR046C"
                     /product="hypothetical protein"
                     /transcript_id="NM_001181933.1"
                     /db_xref="GI:296146584"
                     /db_xref="GeneID:850735"
     CDS             complement(238001..238813)
                     /locus_tag="YLR046C"
                     /note="Putative membrane protein; member of the fungal
                     lipid-translocating exporter (LTE) family of proteins;
                     transcription is activated by paralogous transcription
                     factors Yrm1p and Yrr1p along with genes involved in
                     multidrug resistance; YLR046C has a paralog, RTA1, that
                     arose from the whole genome duplication"
                     /codon_start=1
                     /product="hypothetical protein"
                     /protein_id="NP_013147.1"
                     /db_xref="GI:6323075"
                     /db_xref="SGD:S000004036"
                     /db_xref="GeneID:850735"
                     /translation="MATHTSKRRIHRWENNELSEENSTIIYFPARGLMWTHFPFVLGI
                     CLEFVGYVLKIVFINSPSISTFIAQSVLLLIAPSLYALSIFMLFSKMARLILMEAYML
                     IPAKFSTVSFVVADMIGRVLQAVGGGLLSSWNSRNTGRILIIVGLFIQIFCYTFLTFS
                     QLFLHYKMKATPSKIVRDSNEWFQYNFILLAGILLVNGRTIVRVVQFLMGLQSYIGQH
                     EWCLYVFDTVLMFLLPLIFLATFRARNLFKLQDKSVNIQLNKLLDKESVSED"
     gene            complement(<239347..>241407)
                     /gene="FRE8"
                     /locus_tag="YLR047C"
                     /db_xref="GeneID:850736"
     mRNA            complement(<239347..>241407)
                     /gene="FRE8"
                     /locus_tag="YLR047C"
                     /product="Fre8p"
                     /transcript_id="NM_001181934.1"
                     /db_xref="GI:296146585"
                     /db_xref="GeneID:850736"
     CDS             complement(239347..241407)
                     /gene="FRE8"
                     /locus_tag="YLR047C"
                     /EC_number="1.16.1.7"
                     /note="Protein with sequence similarity to iron/copper
                     reductases; involved in iron homeostasis; deletion mutant
                     has iron deficiency/accumulation growth defects;
                     expression increased in the absence of copper-responsive
                     transcription factor Mac1p"
                     /codon_start=1
                     /product="Fre8p"
                     /protein_id="NP_013148.1"
                     /db_xref="GI:6323076"
                     /db_xref="SGD:S000004037"
                     /db_xref="GeneID:850736"
                     /translation="MNLKSIVSWFKEHLPSFDVDVDKHFRTLRVRKYSQICLLISFII
                     ICVIIPLMNYLLLTDKFFKICHHLKHHVFNRRSWVHKTHMYHKQSLQLCLICFVFTSF
                     FVIQGANGDLLEITKRMGRISVALMPPLLFLTLRPSPLPHTLYLALLPLHKWISRIVV
                     LESILHTWFYLYYMYINDTLYVKMRKLPNIYGVIALGLFLLIAITSVRYARRWSYRVF
                     YYVHYVSTWLILVFLHYHARPGISYYTTLNVLILTGQIVYRLHITNVTRVTIVPISSS
                     LSLLEFPLTDLPKKPILPGGHLRINIYHRNFLRRFFSHLIPFQHPFTIASIPSDNLVR
                     LIIRNGHFPLRTNEKYYITGAFEPELSFISKPTVPFNITTKSSKNPFRNNSSALINSP
                     LNFLIKAQRVFMCVGGSGISFGLPLLRILNFNGVNVRLLWVSRDYKDLEVLNHFKNNF
                     EGMEIYISGTEGNEQDIEIDYIDYHDCAADINDEVRSISSSGRVSELGDNSMLSDGNP
                     QPTEPNENTALLSKKSTLRNHHPPKTSDIPDINADDEIDFTYAFSRSKSRKNTAQGTL
                     TTHSSFNGSSVFRQPKIIEPPAQDPCLEAAPKKIRIPAGVKVFFGRPTLGDKDYEWCL
                     QTECDAETDSIQCCRWANQGRDHAEYLSQVWVLAAGPRGLIESTKRWATDGGLHFHGE
                     SFAL"
     gene            <242232..>243349
                     /gene="RPS0B"
                     /locus_tag="YLR048W"
                     /gene_synonym="NAB1B; YST2"
                     /db_xref="GeneID:850737"
     mRNA            join(<242232..242321,242681..>243349)
                     /gene="RPS0B"
                     /locus_tag="YLR048W"
                     /gene_synonym="NAB1B; YST2"
                     /product="ribosomal 40S subunit protein S0B"
                     /transcript_id="NM_001181935.1"
                     /db_xref="GI:296146586"
                     /db_xref="GeneID:850737"
     CDS             join(242232..242321,242681..243349)
                     /gene="RPS0B"
                     /locus_tag="YLR048W"
                     /gene_synonym="NAB1B; YST2"
                     /note="Protein component of the small (40S) ribosomal
                     subunit; RPS0B has a paralog, RPS0A, that arose from the
                     whole genome duplication; required for maturation of 18S
                     rRNA along with Rps0Ap; deletion of either RPS0 gene
                     reduces growth rate, deletion of both genes is lethal;
                     homologous to human ribosomal protein SA and bacterial S2"
                     /codon_start=1
                     /product="ribosomal 40S subunit protein S0B"
                     /protein_id="NP_013149.1"
                     /db_xref="GI:6323077"
                     /db_xref="SGD:S000004038"
                     /db_xref="GeneID:850737"
                     /translation="MSLPATFDLTPEDAQLLLAANTHLGARNVQVHQEPYVFNARPDG
                     VHVINVGKTWEKLVLAARIIAAIPNPEDVVAISSRTYGQRAVLKFAAHTGATPIAGRF
                     TPGSFTNYITRSFKEPRLVIVTDPRLDAQAIKEASYVNIPVIALTDLDSPSEFVDVAI
                     PCNNRGKHSIGLIWYLLAREVLRLRGALVDRTQPWSIMPDLYFYRNPEEVEQVAEEAA
                     AAEEGEEEEVKEEVTEGQAEATEWAEENADNVEW"
     gene            complement(<243886..>245172)
                     /locus_tag="YLR049C"
                     /db_xref="GeneID:850738"
     mRNA            complement(<243886..>245172)
                     /locus_tag="YLR049C"
                     /product="hypothetical protein"
                     /transcript_id="NM_001181936.1"
                     /db_xref="GI:296146587"
                     /db_xref="GeneID:850738"
     CDS             complement(243886..245172)
                     /locus_tag="YLR049C"
                     /codon_start=1
                     /product="hypothetical protein"
                     /protein_id="NP_013150.1"
                     /db_xref="GI:6323078"
                     /db_xref="SGD:S000004039"
                     /db_xref="GeneID:850738"
                     /translation="MVNNIMHEYVPPSQRLFHSRHRITRNDLKEEALHSGTTDWTTIL
                     DTTIDKDTNLISYAVPIIDNFAIPRANSQGSPVAPSPNHRSTMYSSSSSSASSVFSDG
                     LFTPNNNRNSSGSSSLVIRPQKNLSVDSLIQENKRKINSEKESLSLIANNNDETLCTH
                     TDPSIQNLIKSETKRNILNLKFQNRNLFRRELKLEKFWSNLRSCHTSGDETDLLLVIS
                     KHNLYWFGIPNDFRLPIYKRCLYHYSELDEAGFFSQYANNSLYLAIRKCCNNEEQETL
                     SRSIFINLTKNVTWLNSRFDDNKDNKNSYTVTEGKFYQDFPNLYYHLKDKLKLNVIMD
                     FIKPVIRNFMTNALNKHKLDGIGLELLDILIVTTYYGPNKINAFLMDTFILNLLKQCH
                     YKFFVSNISELVIQISKIDCDLVILLEDLRSRIDLD"
     gene            complement(<245587..>246072)
                     /locus_tag="YLR050C"
                     /db_xref="GeneID:850739"
     mRNA            complement(<245587..>246072)
                     /locus_tag="YLR050C"
                     /product="hypothetical protein"
                     /transcript_id="NM_001181937.1"
                     /db_xref="GI:296146588"
                     /db_xref="GeneID:850739"
     CDS             complement(245587..246072)
                     /locus_tag="YLR050C"
                     /note="hypothetical protein; green fluorescent protein
                     (GFP)-fusion protein localizes to the endoplasmic
                     reticulum; YLR050C is not an essential gene"
                     /codon_start=1
                     /product="hypothetical protein"
                     /protein_id="NP_013151.1"
                     /db_xref="GI:6323079"
                     /db_xref="SGD:S000004040"
                     /db_xref="GeneID:850739"
                     /translation="MKLGHREQQFYLWYFIVHIPITIFIDSSVVIPAKWQLGIAQKVV
                     SDHIAKQHDFLLSEKPEWLYWFVVLELVLQLPLFVYFVNKFWNSSELQVNTNSRLKKW
                     LRIYGWNASLTTLICIVVIFKRGYIPYDVLKTSLSMTQKCQLASVYLPTFLIPLRLCF
                     V"
     gene            complement(<246324..>246977)
                     /gene="FCF2"
                     /locus_tag="YLR051C"
                     /db_xref="GeneID:850740"
     mRNA            complement(<246324..>246977)
                     /gene="FCF2"
                     /locus_tag="YLR051C"
                     /product="Fcf2p"
                     /transcript_id="NM_001181938.1"
                     /db_xref="GI:296146589"
                     /db_xref="GeneID:850740"
     CDS             complement(246324..246977)
                     /gene="FCF2"
                     /locus_tag="YLR051C"
                     /note="Nucleolar protein involved in the early steps of
                     35S rRNA processing; interacts with Faf1p; member of a
                     transcriptionally co-regulated set of genes called the RRB
                     regulon; essential gene"
                     /codon_start=1
                     /product="Fcf2p"
                     /protein_id="NP_013152.1"
                     /db_xref="GI:6323080"
                     /db_xref="SGD:S000004041"
                     /db_xref="GeneID:850740"
                     /translation="MDQSVEDLFGALRDASASLEVKNSAKEQVSLQQEDVLQIGNNDD
                     EVEIESKFQEIETNLKKLPKLETGFDALANKKKKKNVLPSVETEDKRKPNKSDKNDND
                     WFTLPKPDDNMRREVQRDLLLIKHRAALDPKRHYKKQRWEVPERFAIGTIIEDKSEFY
                     SSRMNRKERKSTILETLMGDEASNKYFKRKYNEIQEKSTSGRKAHYKKMKEMRKKRR"
     gene            <247201..>247953
                     /gene="IES3"
                     /locus_tag="YLR052W"
                     /db_xref="GeneID:850741"
     mRNA            <247201..>247953
                     /gene="IES3"
                     /locus_tag="YLR052W"
                     /product="Ies3p"
                     /transcript_id="NM_001181939.1"
                     /db_xref="GI:296146590"
                     /db_xref="GeneID:850741"
     CDS             247201..247953
                     /gene="IES3"
                     /locus_tag="YLR052W"
                     /note="Subunit of the INO80 chromatin remodeling complex"
                     /codon_start=1
                     /product="Ies3p"
                     /protein_id="NP_013153.1"
                     /db_xref="GI:6323081"
                     /db_xref="SGD:S000004042"
                     /db_xref="GeneID:850741"
                     /translation="MKFEDLLATNKQVQFAHAATQHYKSVKTPDFLEKDPHHKKFHNA
                     DGLNQQGSSTPSTATDANAASTASTHTNTTTFKRHIVAVDDISKMNYEMIKNSPGNVI
                     TNANQDEIDISTLKTRLYKDNLYAMNDNFLQAVNDQIVTLNAAEQDQETEDPDLSDDE
                     KIDILTKIQENLLEEYQKLSQKERKWFILKELLLDANVELDLFSNRGRKASHPIAFGA
                     VAIPTNVNANSLAFNRTKRRKINKNGLLENIL"
     gene            complement(<248100..>248426)
                     /locus_tag="YLR053C"
                     /db_xref="GeneID:850742"
     mRNA            complement(<248100..>248426)
                     /locus_tag="YLR053C"
                     /product="hypothetical protein"
                     /transcript_id="NM_001181940.1"
                     /db_xref="GI:296146591"
                     /db_xref="GeneID:850742"
     CDS             complement(248100..248426)
                     /locus_tag="YLR053C"
                     /codon_start=1
                     /product="hypothetical protein"
                     /protein_id="NP_013154.1"
                     /db_xref="GI:6323082"
                     /db_xref="SGD:S000004043"
                     /db_xref="GeneID:850742"
                     /translation="MDMLHNKCSDAIKSTSNSNLSNEVDKQKLQYDDLGNTGFSELFE
                     MESQDNNDSIEDFLFFNINLTQEVEFENQRQYEHTKKTKKHNPFYVPSEVVREMVKKH
                     ALNGRI"
     gene            complement(<248717..>250978)
                     /gene="OSW2"
                     /locus_tag="YLR054C"
                     /db_xref="GeneID:850743"
     mRNA            complement(join(<248717..250860,250948..>250978))
                     /gene="OSW2"
                     /locus_tag="YLR054C"
                     /product="Osw2p"
                     /transcript_id="NM_001181941.1"
                     /db_xref="GI:296146592"
                     /db_xref="GeneID:850743"
     CDS             complement(join(248717..250860,250948..250978))
                     /gene="OSW2"
                     /locus_tag="YLR054C"
                     /note="hypothetical protein reputedly involved in spore
                     wall assembly"
                     /codon_start=1
                     /product="Osw2p"
                     /protein_id="NP_013155.2"
                     /db_xref="GI:37362678"
                     /db_xref="SGD:S000004044"
                     /db_xref="GeneID:850743"
                     /translation="MEENQLTCLIVGETPAAQFLGWRLSLSNSFIILVSQYVSSDELV
                     AWKSTKLGANFYTPNILTKDIKELHHKLKHNGANTYSIDIVLVSAISLQSFETTCRLL
                     SDYTNDNTTVLISTDFGCELEPIAISYFGGKCKCVISISCEVECRQLSLGSYALVNDD
                     QCVITLGLTYCDANFEASPTILENTKAASLELQGIKGSNVRRFLLGLTVAKWMKSKLI
                     LDPKQMALKMWELLIPKISLNILSIIYEQFDYEKMLENKSTEIIFKDLVKELLGICFA
                     QCGSKIARFLLVKSQGEEEINFGKIVEYCKGKKLQLINSTANEHPEYLSLPFEPYCFY
                     HRFEYPAQILLHQPIILAKKYGVSCSNLNFLYGFYTRLLTLSGLSINGGRCEHALSML
                     DSRIGGGINVASGINSGQDFTDGDNEDQDKGKNRVDKNVKEGSFISLTQRFTMTSPLG
                     VNDPALPADLEKLYLGAEYISNCDANTSGGQKRVKSPTKADTGYDDKHLPDDTIHTFE
                     DEYLADEDDFSCLGIDKRSSTKPTKPLEKFGVVAVPHFIRRFSIKRSSKDKSNDMKRP
                     YTTSSLELQLRSNHFMFAKEYQDLHRQLYYEVKPRTQSELDARRRNYSELESQMWKIK
                     HRFNIHRGALPRPRTNPYELLLDHIDVLNRGNTGDILRFTTSRYGGVDTYDSILRDQS
                     TIMELLDKRCAYSPPVLFDNEAKERDHDRDCYQDYNHDHRSH"
     gene            complement(<251272..>253080)
                     /gene="SPT8"
                     /locus_tag="YLR055C"
                     /db_xref="GeneID:850744"
     mRNA            complement(<251272..>253080)
                     /gene="SPT8"
                     /locus_tag="YLR055C"
                     /product="Spt8p"
                     /transcript_id="NM_001181942.1"
                     /db_xref="GI:296146593"
                     /db_xref="GeneID:850744"
     CDS             complement(251272..253080)
                     /gene="SPT8"
                     /locus_tag="YLR055C"
                     /note="Subunit of the SAGA transcriptional regulatory
                     complex; not present in SAGA-like complex SLIK/SALSA;
                     required for SAGA-mediated inhibition at some promoters"
                     /codon_start=1
                     /product="Spt8p"
                     /protein_id="NP_013156.1"
                     /db_xref="GI:6323084"
                     /db_xref="SGD:S000004045"
                     /db_xref="GeneID:850744"
                     /translation="MDEVDDILINNQVVDDEEDDEEMLSGLENDSKQDLEGNDDGGED
                     EEDDDDDDEDDDDDEDEREDDDEQEDDDGEDDAARMDKTATPTNEHQHDEQKAAAAGA
                     GGAGDSGDAVTKIGSEDVKLSDVDGGVGSREASSSTHEASANGEVYEYYKHMLNAAQI
                     ADSYNIYPTAAIPIQTHVNALAVSRGLKYLFLGGSDGYIRKYDLLNTLEGKLSLTILQ
                     KHSLAESIQNAGILQSYWENEIPQKKSEMKLSANKTDYEPKVSPVHSLEVQSECLFIL
                     SGLQNGGITMQGVRYMEGSIAHYFKGRNGHTQIVNILRLNGQEDRFLSGSWDKRLLEW
                     DLQTGDIVNEFKKSRSELSSLEMRPLYSSVDVSGNVNSGKENENADDDMDSLFGDEDE
                     DEKQDAGNEPVETGDGSNGEENKEQISEESLNIVYDESVFMTSGLNGSVHIWDRRMTQ
                     SPALSLERGAGVPPWCLSACWGVDGDHVYAGRRNACVEQFDLKMPSKPIHNLKLPSIS
                     GPVSCVKAMPNNKHLLCASRDNIRLYNVEIAVDASNSTTKSSKVPFLIVPGHHGGIIS
                     NLYLDPTSRFIISTSGNRGWQGNSTDTTLIYDIDLE"
     gene            <253861..>254958
                     /gene="ERG3"
                     /locus_tag="YLR056W"
                     /gene_synonym="PSO6; SYR1"
                     /db_xref="GeneID:850745"
     mRNA            <253861..>254958
                     /gene="ERG3"
                     /locus_tag="YLR056W"
                     /gene_synonym="PSO6; SYR1"
                     /product="C-5 sterol desaturase"
                     /transcript_id="NM_001181943.1"
                     /db_xref="GI:296146594"
                     /db_xref="GeneID:850745"
     CDS             253861..254958
                     /gene="ERG3"
                     /locus_tag="YLR056W"
                     /gene_synonym="PSO6; SYR1"
                     /EC_number="1.3.3.-"
                     /note="C-5 sterol desaturase; glycoprotein that catalyzes
                     the introduction of a C-5(6) double bond into episterol, a
                     precursor in ergosterol biosynthesis; mutants are viable,
                     but cannot grow on non-fermentable carbon sources;
                     substrate of the HRD ubiquitin ligase"
                     /codon_start=1
                     /product="C-5 sterol desaturase"
                     /protein_id="NP_013157.1"
                     /db_xref="GI:6323085"
                     /db_xref="SGD:S000004046"
                     /db_xref="GeneID:850745"
                     /translation="MDLVLEVADHYVLDDLYAKVLPASLAANIPVKWQKLLGLNSGFS
                     NSTILQETLNSKNAVKECRRFYGQVPFLFDMSTTSFASLLPRSSILREFLSLWVIVTI
                     FGLLLYLFTASLSYVFVFDKSIFNHPRYLKNQMAMEIKLAVSAIPWMSMLTVPWFVME
                     LNGHSKLYMKIDYENHGVRKLIIEYFTFIFFTDCGVYLAHRWLHWPRVYRALHKPHHK
                     WLVCTPFASHSFHPVDGFLQSISYHIYPLILPLHKVSYLILFTFVNFWTVMIHDGQYL
                     SNNPAVNGTACHTVHHLYFNYNYGQFTTLWDRLGGSYRRPDDSLFDPKLRDAKETWDA
                     QVKEVEHFIKEVEGDDNDRIYENDPNTKKNN"
     gene            <255306..>257855
                     /gene="MNL2"
                     /locus_tag="YLR057W"
                     /db_xref="GeneID:850746"
     mRNA            <255306..>257855
                     /gene="MNL2"
                     /locus_tag="YLR057W"
                     /product="putative mannosidase MNL2"
                     /transcript_id="NM_001181944.1"
                     /db_xref="GI:296146595"
                     /db_xref="GeneID:850746"
     CDS             255306..257855
                     /gene="MNL2"
                     /locus_tag="YLR057W"
                     /EC_number="3.2.1.-"
                     /note="Putative mannosidase involved in ER-associated
                     protein degradation; localizes to the endoplasmic
                     reticulum; sequence similarity with seven-hairpin
                     glycosidase (GH47) family members, such as Mns1p and
                     Mnl1p, that hydrolyze 1,2-linked alpha-D-mannose residues;
                     non-essential gene"
                     /codon_start=1
                     /product="putative mannosidase MNL2"
                     /protein_id="NP_013158.1"
                     /db_xref="GI:6323086"
                     /db_xref="SGD:S000004047"
                     /db_xref="GeneID:850746"
                     /translation="MSIARLVYSLFRRVRSVLLLFITISLLFYYTFQNEIDILNSYAL
                     NDSLPSINNYEHNTEGSSKLDPPDLSSTGSDRIATDKENGNVAVDLSDPATLREKNKY
                     FPLLLKGSSHQIGSNLPISSLLTYKEKYPVLFEYSSPSLTSISQNDVHKIQPAMQLPP
                     DVDMIKQIKDIFMKSWNQEQLLLKSNLRRESTWPIDLIDSLDTLYLCGETKLFQDSVN
                     IIEDFDFRVPPLAMEVIDIPDITTRVLEGLLSAYELSMDKRLLNKAKHVADFILRSFD
                     TPNRIPILKYFWKSDLRNRFPDRTVPSGQLTTMALAFIRLSQLTRLNKYFDAVERVFT
                     TIRQSYNEFDMEFMLPDVVDASGCQLLTQEEIENGAHLKGSSIMKSINENFKFVHCQQ
                     LGKFLNPPIDDNSLQEQSQYQAYRINEKTVPILENLFKINDLFQSSYDILDGSSKNAN
                     AATMDPSIGSEVEAVDEIIEKRNFKDGTKKDSTKNTVGDKSLIDSQTFLTNSISNIFK
                     FMTFRPMLPKQTENKKFNFLNSILTKSQFMPTTNELDVTIRKSYDVSLYSCRLGGILG
                     LSSRVPHRGGVNTKYILPSSLLEMSEIITESCFMLMEEFDGLLPQKFELDPCTDETNG
                     NCEFNGETKSRMIANGEYETFENDLDVGIKVSNYGKGGNDQKAKRNVLSKDGITETQN
                     IKGDTVGSSKSIAEIDGDEVTQIRRVFTLGKDIKPHITTDDTMGSQWKNHPDWPFWVN
                     KVESRRLLDSNIIESIFYMYRISGEQKWRSMGKQSFGILMQELMELNSGAKGLWQIKE
                     FYENGEKVNNDLPSYWFSRTLKYYLLLFSDGDKVSLDKHILTQGGHIIKKK"
     gene            complement(<257992..>259401)
                     /gene="SHM2"
                     /locus_tag="YLR058C"
                     /gene_synonym="SHMT2"
                     /db_xref="GeneID:850747"
     mRNA            complement(<257992..>259401)
                     /gene="SHM2"
                     /locus_tag="YLR058C"
                     /gene_synonym="SHMT2"
                     /product="glycine hydroxymethyltransferase SHM2"
                     /transcript_id="NM_001181945.1"
                     /db_xref="GI:296146596"
                     /db_xref="GeneID:850747"
     CDS             complement(257992..259401)
                     /gene="SHM2"
                     /locus_tag="YLR058C"
                     /gene_synonym="SHMT2"
                     /EC_number="2.1.2.1"
                     /note="Cytosolic serine hydroxymethyltransferase; converts
                     serine to glycine plus 5,10 methylenetetrahydrofolate;
                     major isoform involved in generating precursors for
                     purine, pyrimidine, amino acid, and lipid biosynthesis"
                     /codon_start=1
                     /product="glycine hydroxymethyltransferase SHM2"
                     /protein_id="NP_013159.1"
                     /db_xref="GI:6323087"
                     /db_xref="SGD:S000004048"
                     /db_xref="GeneID:850747"
                     /translation="MPYTLSDAHHKLITSHLVDTDPEVDSIIKDEIERQKHSIDLIAS
                     ENFTSTSVFDALGTPLSNKYSEGYPGARYYGGNEHIDRMEILCQQRALKAFHVTPDKW
                     GVNVQTLSGSPANLQVYQAIMKPHERLMGLYLPDGGHLSHGYATENRKISAVSTYFES
                     FPYRVNPETGIIDYDTLEKNAILYRPKVLVAGTSAYCRLIDYKRMREIADKCGAYLMV
                     DMAHISGLIAAGVIPSPFEYADIVTTTTHKSLRGPRGAMIFFRRGVRSINPKTGKEVL
                     YDLENPINFSVFPGHQGGPHNHTIAALATALKQAATPEFKEYQTQVLKNAKALESEFK
                     NLGYRLVSNGTDSHMVLVSLREKGVDGARVEYICEKINIALNKNSIPGDKSALVPGGV
                     RIGAPAMTTRGMGEEDFHRIVQYINKAVEFAQQVQQSLPKDACRLKDFKAKVDEGSDV
                     LNTWKKEIYDWAGEYPLAV"
     gene            complement(<259738..>260547)
                     /gene="REX2"
                     /locus_tag="YLR059C"
                     /gene_synonym="YNT20"
                     /db_xref="GeneID:850748"
     mRNA            complement(<259738..>260547)
                     /gene="REX2"
                     /locus_tag="YLR059C"
                     /gene_synonym="YNT20"
                     /product="Rex2p"
                     /transcript_id="NM_001181946.1"
                     /db_xref="GI:296146597"
                     /db_xref="GeneID:850748"
     CDS             complement(259738..260547)
                     /gene="REX2"
                     /locus_tag="YLR059C"
                     /gene_synonym="YNT20"
                     /EC_number="3.1.-.-"
                     /note="3'-5' RNA exonuclease; involved in 3'-end
                     processing of U4 and U5 snRNAs, 5S and 5.8S rRNAs, and
                     RNase P and RNase MRP RNA; localized to mitochondria and
                     null suppresses escape of mtDNA to nucleus in yme1 yme2
                     mutants; RNase D exonuclease"
                     /codon_start=1
                     /product="Rex2p"
                     /protein_id="NP_013160.1"
                     /db_xref="GI:6323088"
                     /db_xref="SGD:S000004049"
                     /db_xref="GeneID:850748"
                     /translation="MKWLLFPARIVARTRPNLFSLYRRSVSQYLRPRTIQNLQSMAQT
                     PELKTKLFKPLVWIDCEMTGLDHVNDRIIEICCIITDGHLAPVKAADGQGDSHYESVI
                     HYGPEVMNKMNEWCIEHHGNSGLTAKVLASEKTLAQVEDELLEYIQRYIPDKNVGVLA
                     GNSVHMDRLFMVREFPKVIDHLFYRIVDVSSIMEVARRHNPALQARNPKKEAAHTAYS
                     DIKESIAQLQWYMDNYLKPPQETESVESIGSEQPESPSSSTSSLKRQRTDF"
     gene            <260979..>262766
                     /gene="FRS1"
                     /locus_tag="YLR060W"
                     /db_xref="GeneID:850749"
     mRNA            <260979..>262766
                     /gene="FRS1"
                     /locus_tag="YLR060W"
                     /product="phenylalanine--tRNA ligase subunit beta"
                     /transcript_id="NM_001181947.1"
                     /db_xref="GI:296146598"
                     /db_xref="GeneID:850749"
     CDS             260979..262766
                     /gene="FRS1"
                     /locus_tag="YLR060W"
                     /EC_number="6.1.1.20"
                     /note="Beta subunit of cytoplasmic phenylalanyl-tRNA
                     synthetase; forms a tetramer with Frs2p to generate active
                     enzyme; able to hydrolyze mis-aminoacylated tRNA-Phe,
                     which could contribute to translational quality control"
                     /codon_start=1
                     /product="phenylalanine--tRNA ligase subunit beta"
                     /protein_id="NP_013161.1"
                     /db_xref="GI:6323089"
                     /db_xref="SGD:S000004050"
                     /db_xref="GeneID:850749"
                     /translation="MPTVSVNKQQLFDLLGKNYTSQEFDELCFEFGMEMDEDTTEEAL
                     KTGEEPELKLDISANRYDLLCIEGISQSLNEYLERKERPDYKLSKPTTKLIIDKSTEQ
                     IRPFATAAVLRNIKLNEKSYASFIALQDKLHANLCRNRSLVAMGTHDLDSIEGPFHYR
                     ALPPKDIKFVPLNQTQEFTGDKLIEFYKSPEQKNNIGRYVHIIEDSPVFPVIMDSKDR
                     VCSLPPLINSEHSKISVNTRNILIDITATDKTKAEIVLNILTTMFSRYCDEPFTVEPV
                     EIVSEHNGQSRLAPNFNDRIMDVSIKYINSCLGLDQSADEIAHCLKKMSLHAVQSKED
                     KDILHVDIPVTRPDILHACDIMEDAAVGYGFNNLPKGEKLSNANFIAKPLPINKVSDI
                     FRVASSQATWVEVLPLTLCSHDENFKFLRQSDNGDLAVKLANPKTLEYQVVRTTLLPG
                     ILKTVKENRKHSLPIKVFETGDVVFKDDKLERKAYNERHWAAIYVGKNSGFEIIQGLL
                     GKIMQTFRTEWIADYGAAASGRGYWIEEDDSVKTYFPGRGAKVMFRSKEGAEPKQIGH
                     LGVLHPEVMMNFDVPFAASFVEVNAEVFL"
     gene            <263194..>263948
                     /gene="RPL22A"
                     /locus_tag="YLR061W"
                     /db_xref="GeneID:850750"
     mRNA            join(<263194..263205,263595..>263948)
                     /gene="RPL22A"
                     /locus_tag="YLR061W"
                     /product="ribosomal 60S subunit protein L22A"
                     /transcript_id="NM_001181948.1"
                     /db_xref="GI:296146599"
                     /db_xref="GeneID:850750"
     CDS             join(263194..263205,263595..263948)
                     /gene="RPL22A"
                     /locus_tag="YLR061W"
                     /note="Ribosomal 60S subunit protein L22A; required for
                     the oxidative stress response in yeast; homologous to
                     mammalian ribosomal protein L22, no bacterial homolog;
                     RPL22A has a paralog, RPL22B, that arose from the whole
                     genome duplication"
                     /codon_start=1
                     /product="ribosomal 60S subunit protein L22A"
                     /protein_id="NP_013162.1"
                     /db_xref="GI:6323090"
                     /db_xref="SGD:S000004051"
                     /db_xref="GeneID:850750"
                     /translation="MAPNTSRKQKIAKTFTVDVSSPTENGVFDPASYAKYLIDHIKVE
                     GAVGNLGNAVTVTEDGTVVTVVSTAKFSGKYLKYLTKKYLKKNQLRDWIRFVSTKTNE
                     YRLAFYQVTPEEDEEEDEE"
     gene            <264157..>265254
                     /gene="BMT6"
                     /locus_tag="YLR063W"
                     /db_xref="GeneID:850752"
     mRNA            <264157..>265254
                     /gene="BMT6"
                     /locus_tag="YLR063W"
                     /product="Bmt6p"
                     /transcript_id="NM_001181950.1"
                     /db_xref="GI:296146600"
                     /db_xref="GeneID:850752"
     CDS             264157..265254
                     /gene="BMT6"
                     /locus_tag="YLR063W"
                     /note="Methyltransferase required for m3U2843 methylation
                     of the 25S rRNA; S-adenosylmethionine-dependent; green
                     fluorescent protein (GFP)-fusion protein localizes to the
                     cytoplasm; YLR063W is not an essential gene"
                     /codon_start=1
                     /product="Bmt6p"
                     /protein_id="NP_013164.1"
                     /db_xref="GI:6323092"
                     /db_xref="SGD:S000004053"
                     /db_xref="GeneID:850752"
                     /translation="MLLMRRFAFLTSSVYFKYIPIYSQYHYSSQFPINMNPKKVAQLP
                     VHNKSTLPPQEIIDLFKITFLEELYPKDQDNEKSPLTEQIQAVKSDLYNRDYNAAFNN
                     DSKRIAYCCRWSPSRATSYASVFAHFPELLKIIRCEIDDKDSNVLCIGGGAGGELVAL
                     ASIFTLSRDFSSKFASALKIDNEVNKKPRNLNIQLVDIADWSTVVEKLTATIKSKWLY
                     GDSEAESFNVNFTHKDCLQMTEPQDIKIYQGLDLITLLFTTNELFTQKKVESIKFLQR
                     LNENCAPGCHLLILESAGSYSHITINNKKFPIQFLIDTILVGNRKDKGTTGPWSLVSE
                     NDSIWYRMDPKLDYSIPLENMRFFYRLYVKN"
     gene            <265456..>266277
                     /gene="PER33"
                     /locus_tag="YLR064W"
                     /db_xref="GeneID:850753"
     mRNA            <265456..>266277
                     /gene="PER33"
                     /locus_tag="YLR064W"
                     /product="Per33p"
                     /transcript_id="NM_001181951.1"
                     /db_xref="GI:296146601"
                     /db_xref="GeneID:850753"
     CDS             265456..266277
                     /gene="PER33"
                     /locus_tag="YLR064W"
                     /note="Protein that localizes to the endoplasmic
                     reticulum; also associates with the nuclear pore complex;
                     deletion extends chronological lifespan; highly conserved
                     across species, orthologous to human TMEM33 and paralogous
                     to Pom33p; protein abundance increases in response to DNA
                     replication stress"
                     /codon_start=1
                     /product="Per33p"
                     /protein_id="NP_013165.1"
                     /db_xref="GI:6323093"
                     /db_xref="SGD:S000004054"
                     /db_xref="GeneID:850753"
                     /translation="MTVPRNRPMAPFGTIIKSRIKQPQFYWFIGHFLTIFNFIQFHLS
                     ITSKQNQLSCYRRSLFYISVTYAIVLYQFFKSDQLKFNFTLLRQEMKKLDNLQYFAML
                     FILFLLSQFNIIISGSLYSPVIFSIFHFLNYFKENLLPFLPLIPLNLKNLLNSKITVF
                     IQNYNGFFLQMAQVFEIICGLRVGLFLVPFNFFLLLVRRANVSFEVVGTMLAGLTYVW
                     FFKLRYLQSESMRQIFKQYVLRLDAYVSRTLPPYCSRLWNGYKNFVMTVFWKIPV"
     gene            complement(<266373..>266918)
                     /gene="ENV10"
                     /locus_tag="YLR065C"
                     /db_xref="GeneID:850754"
     mRNA            complement(<266373..>266918)
                     /gene="ENV10"
                     /locus_tag="YLR065C"
                     /product="Env10p"
                     /transcript_id="NM_001181952.1"
                     /db_xref="GI:296146602"
                     /db_xref="GeneID:850754"
     CDS             complement(266373..266918)
                     /gene="ENV10"
                     /locus_tag="YLR065C"
                     /note="Protein proposed to be involved in vacuolar
                     functions; putative role in secretory protein quality
                     control; mutant shows defect in CPY processing; YLR065C is
                     not an essential gene"
                     /codon_start=1
                     /product="Env10p"
                     /protein_id="NP_013166.1"
                     /db_xref="GI:6323094"
                     /db_xref="SGD:S000004055"
                     /db_xref="GeneID:850754"
                     /translation="MAGKAGRKQASSNAKIIQGLYKQVSLFLGMAIVRLFISRKVTIG
                     QWIKLVALNVPMFVALYIIVLSGKPKYDGNRVVKQGIDLNDNTNLISYFFDLIYLSLF
                     GNIGIIAFRTFKFWWCLLLCPIYAGYKLYGLKNMFMPGAQQTQADNRSKNANEGQSKS
                     KRQMKRERRGETDSKIKYKYR"
     gene            <267169..>267723
                     /gene="SPC3"
                     /locus_tag="YLR066W"
                     /db_xref="GeneID:850755"
     mRNA            <267169..>267723
                     /gene="SPC3"
                     /locus_tag="YLR066W"
                     /product="Spc3p"
                     /transcript_id="NM_001181953.1"
                     /db_xref="GI:296146603"
                     /db_xref="GeneID:850755"
     CDS             267169..267723
                     /gene="SPC3"
                     /locus_tag="YLR066W"
                     /note="Subunit of signal peptidase complex; complex
                     catalyzes cleavage of N-terminal signal sequences of
                     proteins targeted to the secretory pathway; homologous to
                     mammalian SPC22/23; other members of the complex are
                     Spc1p, Spc2p, and Sec11p"
                     /codon_start=1
                     /product="Spc3p"
                     /protein_id="NP_013167.1"
                     /db_xref="GI:6323095"
                     /db_xref="SGD:S000004056"
                     /db_xref="GeneID:850755"
                     /translation="MFSFVQRFQNVSNQAFSMGIVMVVFIMASSYYQLINNNAFSVPS
                     NIDNVKTLINVRTSRYFGSQRGKAKENMKIKFDLNTDLTPLFNWNTKQVFVYLTAEYN
                     STEKITSEVTFWDKIIKSKDDAVIDVNDLRSKYSIWDIEDGKFEGKDLVFKLHWNVQP
                     WVGLLTYGETVGNYTLTVENKNKV"
     gene            complement(<267813..>270710)
                     /gene="PET309"
                     /locus_tag="YLR067C"
                     /db_xref="GeneID:850756"
     mRNA            complement(<267813..>270710)
                     /gene="PET309"
                     /locus_tag="YLR067C"
                     /product="Pet309p"
                     /transcript_id="NM_001181954.1"
                     /db_xref="GI:296146604"
                     /db_xref="GeneID:850756"
     CDS             complement(267813..270710)
                     /gene="PET309"
                     /locus_tag="YLR067C"
                     /note="Specific translational activator for the COX1 mRNA;
                     also influences stability of intron-containing COX1
                     primary transcripts; localizes to the mitochondrial inner
                     membrane; contains seven pentatricopeptide repeats (PPRs)"
                     /codon_start=1
                     /product="Pet309p"
                     /protein_id="NP_013168.1"
                     /db_xref="GI:6323096"
                     /db_xref="SGD:S000004057"
                     /db_xref="GeneID:850756"
                     /translation="MKRCAPAVLRNYNYKKGIWSTGVPDHIRKLLRDKSTSPLCSQDE
                     RNLVSYFMARGSVPLKSVGSGLTKKATTSITSNSATTTFERQYLIKYLYRHQAYGNVI
                     KIAQKFLYTTIGSQRLLKQDASLPELKKFLLSLLILQRGIQLDQAISDIIQRFLLTQK
                     TMVIDLINSIFSRMVIMNMHEEAVYKWVKWMKLVNGHCEFTNYMENKIVLRNFLSFMR
                     QSNVRPDYLSYLKAIQLTQGPAIASQFATTLLFLLTYIRKFSSAEAVWNYKCEHNLPI
                     VSSDLTCILKTYCHMQKFNLVSSTYWKYPDAQHDQNQFDYLLVAHSRLHNWDALQQQF
                     NALFGIGKLPSIQHYGILMYTMARIGELDSVNKLYTQLLRRGMIPTYAVLQSLLYAHY
                     KVGDFAACFSHFELFKKYDITPSTATHTIMLKVYRGLNDLDGAFRILKRLSEDPSVEI
                     TEGHFALLIQMCCKTTNHLIAQELFNLMTEHYNIQHTGKSISALMDVYIESNRPTEAI
                     ALFEKHSKNLSWRDGLISVYNKAIKAYIGLRNANKCEELFDKITTSKLAVNSEFYKMM
                     IKFLVTLNEDCETALSIIDQLIKHSVIKVDATHFEIIMEAYDKEGYRDGIINLYKTMS
                     QNKVPANSKILYYILKAVAKKSLQNNEEIKETINMVEDIMENAANGTLDVTYNKLHPS
                     VMAWPMRMIVKHDSPQRALELYNRYNELFFKKHDWISNNNKFVMMRSLLVLLAQIEQW
                     KDFETLFAKYMDRIENIENLPSSTTPNIKLRSIFSGLFPYKVSQLIAMNKIDELPLLW
                     KKLREKGFILDNISWNSAVEALFKDPRTLSYGMKIVDDTLIHGYNLIHKFRLLTKLSE
                     DKTQSSDKSWPTLKMKEKEPNKFQPRLYLKSDTYNSIMRQLDTYLDGIDDLKTLEDQV
                     RDFISNYKYFMKDYLLMPRSKINKWEQIEMRHLSYFKELRKSKRVLPVSKF"
     gene            <271008..>271463
                     /gene="FYV7"
                     /locus_tag="YLR068W"
                     /db_xref="GeneID:850757"
     mRNA            <271008..>271463
                     /gene="FYV7"
                     /locus_tag="YLR068W"
                     /product="Fyv7p"
                     /transcript_id="NM_001181955.1"
                     /db_xref="GI:296146605"
                     /db_xref="GeneID:850757"
     CDS             271008..271463
                     /gene="FYV7"
                     /locus_tag="YLR068W"
                     /note="Essential protein required for maturation of 18S
                     rRNA; required for survival upon exposure to K1 killer
                     toxin"
                     /codon_start=1
                     /product="Fyv7p"
                     /protein_id="NP_013169.1"
                     /db_xref="GI:6323097"
                     /db_xref="SGD:S000004058"
                     /db_xref="GeneID:850757"
                     /translation="MGTAKQNQNRKKFTREYKVKEIQRSITKKTRLRKEYLKALKDEG
                     YAVPEKEPKTVAKESVRKIKEARAIEGKKKLDEKKEIKKQRKRMQKDELNKQRNEQLE
                     RIRVSKEKFQRREDRKKKLTQRTRTGQPLMGPKIEDLLDKIKTDDTYTS"
     gene            complement(<271630..>273915)
                     /gene="MEF1"
                     /locus_tag="YLR069C"
                     /db_xref="GeneID:850758"
     mRNA            complement(<271630..>273915)
                     /gene="MEF1"
                     /locus_tag="YLR069C"
                     /product="Mef1p"
                     /transcript_id="NM_001181956.1"
                     /db_xref="GI:296146606"
                     /db_xref="GeneID:850758"
     CDS             complement(271630..273915)
                     /gene="MEF1"
                     /locus_tag="YLR069C"
                     /note="Mitochondrial elongation factor involved in
                     translational elongation"
                     /codon_start=1
                     /product="Mef1p"
                     /protein_id="NP_013170.1"
                     /db_xref="GI:6323098"
                     /db_xref="SGD:S000004059"
                     /db_xref="GeneID:850758"
                     /translation="MSVQKMMWVPRKMVGGRIPFFTCSKVFSGFSRRSFHESPLARST
                     YEEEKVLVDEIKQKLTPDDIGRCNKLRNIGISAHIDSGKTTFTERVLYYTKRIKAIHE
                     VRGRDNVGAKMDSMDLEREKGITIQSAATYCSWDKEGKNYHFNLIDTPGHIDFTIEVE
                     RALRVLDGAVLVVCAVSGVQSQTVTVDRQMRRYNVPRVTFINKMDRMGSDPFRAIEQL
                     NSKLKIPAAAVQIPIGSESSLSGVVDLINRVAIYNKGDNGEIIEKGPVPENLKPLMEE
                     KRQLLIETLADVDDEMAEMFLEEKEPTTQQIKDAIRRSTIARSFTPVLMGSALANTGI
                     QPVLDAIVDYLPNPSEVLNTALDVSNNEAKVNLVPAVQQPFVGLAFKLEEGKYGQLTY
                     VRVYQGRLRKGNYITNVKTGKKVKVARLVRMHSSEMEDVDEVGSGEICATFGIDCASG
                     DTFTDGSVQYSMSSMYVPDAVVSLSITPNSKDASNFSKALNRFQKEDPTFRVKFDPES
                     KETIISGMGELHLEIYVERMRREYNVDCVTGKPQVSYRESITIPADFDYTHKKQSGGA
                     GQYGRVIGTLSPVDDITKGNIFETAIVGGRIPDKYLAACGKGFEEVCEKGPLIGHRVL
                     DVKMLINDGAIHAVDSNELSFKTATMSAFRDAFLRAQPVIMEPIMNVSVTSPNEFQGN
                     VIGLLNKLQAVIQDTENGHDEFTLKAECALSTMFGFATSLRASTQGKGEFSLEFSHYA
                     PTAPHVQKELISEFQKKQAKK"
     gene            complement(<274141..>275211)
                     /gene="XYL2"
                     /locus_tag="YLR070C"
                     /db_xref="GeneID:850759"
     mRNA            complement(<274141..>275211)
                     /gene="XYL2"
                     /locus_tag="YLR070C"
                     /product="D-xylulose reductase XYL2"
                     /transcript_id="NM_001181957.1"
                     /db_xref="GI:296146607"
                     /db_xref="GeneID:850759"
     CDS             complement(274141..275211)
                     /gene="XYL2"
                     /locus_tag="YLR070C"
                     /EC_number="1.1.1.9"
                     /note="Xylitol dehydrogenase; converts xylitol to
                     D-xylulose; expression induced by xylose, even though this
                     pentose sugar is not well utilized by S. cerevisiae; null
                     mutant has cell wall defect"
                     /codon_start=1
                     /product="D-xylulose reductase XYL2"
                     /protein_id="NP_013171.1"
                     /db_xref="GI:6323099"
                     /db_xref="SGD:S000004060"
                     /db_xref="GeneID:850759"
                     /translation="MTDLTTQEAIVLERPGKITLTNVSIPKISDPNEVIIQIKATGIC
                     GSDIHYYTHGRIANYVVESPMVLGHESSGIVALIGENVKTLKVGDRVALEPGIPDRFS
                     PEMKEGRYNLDPNLKFAATPPFDGTLTKYYKTMKDFVYKLPDDVSFEEGALIEPLSVA
                     IHANKLAKIKFGARCVVFGAGPIGLLAGKVASVFGAADVVFVDLLENKLETARQFGAT
                     HIVNSGDLPHGVTVDSVIKKAIGKKGADVVFECSGAEPCVRAGIEVCKAGGTIVQVGM
                     GQEEIQFPISIIPTKELTFQGCFRYCQGDYSDSIELVSSRKLSLKPFITHRYSFKDAV
                     EAFEETSHHPLNNIKTIIEGPE"
     gene            complement(<275378..>278626)
                     /gene="RGR1"
                     /locus_tag="YLR071C"
                     /gene_synonym="MED14"
                     /db_xref="GeneID:850760"
     mRNA            complement(<275378..>278626)
                     /gene="RGR1"
                     /locus_tag="YLR071C"
                     /gene_synonym="MED14"
                     /product="Rgr1p"
                     /transcript_id="NM_001181958.1"
                     /db_xref="GI:296146608"
                     /db_xref="GeneID:850760"
     CDS             complement(275378..278626)
                     /gene="RGR1"
                     /locus_tag="YLR071C"
                     /gene_synonym="MED14"
                     /note="Subunit of the RNA polymerase II mediator complex;
                     associates with core polymerase subunits to form the RNA
                     polymerase II holoenzyme; required for glucose repression,
                     HO repression, RME1 repression and sporulation"
                     /codon_start=1
                     /product="Rgr1p"
                     /protein_id="NP_013172.1"
                     /db_xref="GI:6323100"
                     /db_xref="SGD:S000004061"
                     /db_xref="GeneID:850760"
                     /translation="MTTTIGSPQMLANEERLSNEMHALKNRSEQNGQEQQGPVKNTQL
                     HGPSATDPETTATQKESLEMVPKDTSAATMTSAPPPALPHVEINQVSLALVIRNLTVF
                     TMKELAQYMKTNVHTQANEPNSAKKIRFLQLIIFLRTQFLKLYVLVKWTRTIKQNNFH
                     VLIDLLNWFRTTNMNVNNCIWALKSSLNSMTNAKLPNVDLVTALEVLSLGRPNLPTHN
                     FKLSGVSNSMDMVDGMAKVPIGLILQRLKDLNLTVSIKIALMNIPKPLNSYHIKNGRI
                     YFTVPNEFEIQLSTVNRQSPLFFVDLKLLFNTEAEQTVSAVTEATSTNGDSENNEENS
                     SSNGNNLPLNKPRLEKLINEILLKSNDPLLSLYNFLHKYVLTLQLYMVHREFLKLANG
                     GKFSKSNLIHNYDSKKSTITVRYWLNGKMDSKGKITIGIQRTTESLILKWDNQSASRA
                     KNMPVIYNNIVSNIEGILDEIMFNHARIIRSELLARDIFQEDEENSDVLLFQLPTTCV
                     SMAPIQLKIDLLSGQFYFRNPTPLLSNYASKINRAEGPEELARILQQLKLDKIIHVLT
                     TMFENTGWSCSRIIKIDKPIRTQVNTGGESVVKKEDNKYAIAGNSTTNSDVSLLLQRD
                     LFIRLPHWPLNWYLILSIISSKTSCVVEKRIGKIVSQRGKWNLKYLDNSNVMTVKLES
                     ITYQKIMILQRTILNRIINHMLIDSLNQLEIRNKICSSEMINEQKLPQYIIQGSNTND
                     NISIITLELESFLEGSKALNSILESSMFLRIDYSNSQIRLYAKFKRNTMMIQCQIDKL
                     YIHFVQEEPLAFYLEESFTNLGIIVQYLTKFRQKLMQLVVLTDVVERLHKNFESENFK
                     IIALQPNEISFKYLSNNDEDDKDCTIKISTNDDSIKNLTVQLSPSNPQHIIQPFLDNS
                     KMDYHFIFSYLQFTSSLFKALKVILNERGGKFHESGSQYSTMVNIGLHNLNEYQIVYY
                     NPQAGTKITICIELKTVLHNGRDKIQFHIHFADVAHITTKSPAYPMMHQVRNQVFMLD
                     TKRLGTPESVKPANASHAIRLGNGVACDPSEIEPILMEIHNILKVDSNSSSS"
     gene            <278862..>280943
                     /locus_tag="YLR072W"
                     /db_xref="GeneID:850761"
     mRNA            <278862..>280943
                     /locus_tag="YLR072W"
                     /product="hypothetical protein"
                     /transcript_id="NM_001181959.1"
                     /db_xref="GI:296146609"
                     /db_xref="GeneID:850761"
     CDS             278862..280943
                     /locus_tag="YLR072W"
                     /note="hypothetical protein; green fluorescent protein
                     (GFP)-fusion protein localizes to the cytoplasm in a
                     punctate pattern; not an esssential gene; YLR072W has a
                     paralog, YFL042C, that arose from the whole genome
                     duplication"
                     /codon_start=1
                     /product="hypothetical protein"
                     /protein_id="NP_013173.1"
                     /db_xref="GI:6323101"
                     /db_xref="SGD:S000004062"
                     /db_xref="GeneID:850761"
                     /translation="MWGDSMRELGDAMDNELNAVKPVVEEGGMDGARKFIKGKSFQKS
                     STEHMLISPGRDGSVPLNGLKSSPADPHLSDVNSILDNHRGGGETALTSVNNIIMATS
                     TNGDSDGVDGDAKRPSISNCSSRSSFFDTVLSTFSLKSNSQDTVTNEVKNIEVQFASE
                     EANKKFRQMFKPLAPNTRLITDYFCYFHREFPYQGRIYLSNTHLCFNSTVLNWMAKLQ
                     IPLNEIKYLDKVTTNSSAISVETVTNRYTFSGFIARDEVFQLITRVWSKENLTNINDV
                     LEVDERVSKKKGISSTPSSIFNNVSTNAYNDFISTTTTEPTSRASYMSENDMLIEEAI
                     RSVDDYMGTPRASPSSSSSSSSSSSSLGSSTTYYCRPVYRLKPNAPFQYEGPFHVQET
                     MDFPYKPEANNEYVLLERQFSVPPGLLFIMMFNEDNPVFELSFLKTQDSSNISHIGTF
                     EKVNKDGQHYREFQYTKQLHFPVGPKSTNCEVAEILLHCDWERYINVLSITRTPNVPS
                     GTSFSTRTRYMFRWDDQGQGCILKISFWVDWNASSWIKPMVESNCKNGQISATKDLVK
                     LVEEFVEKYVELSKEKADTLKPLPSVTSFGSPRKVAAPELTMVQPESKPEAEAEISEI
                     GSDRWRFNWVNIIILVLLVLNLLYLMKLNKKMDKLTNLMTHKDEVVAHATLLDIPAKV
                     QWSRPRRGDVL"
     gene            complement(<281019..>281621)
                     /gene="RFU1"
                     /locus_tag="YLR073C"
                     /db_xref="GeneID:850762"
     mRNA            complement(<281019..>281621)
                     /gene="RFU1"
                     /locus_tag="YLR073C"
                     /product="Rfu1p"
                     /transcript_id="NM_001181960.1"
                     /db_xref="GI:296146610"
                     /db_xref="GeneID:850762"
     CDS             complement(281019..281621)
                     /gene="RFU1"
                     /locus_tag="YLR073C"
                     /note="Protein that inhibits Doa4p deubiquitinating
                     activity; contributes to ubiquitin homeostasis by
                     regulating the conversion of free ubiquitin chains to
                     ubiquitin monomers by Doa4p; GFP-fusion protein localizes
                     to endosomes"
                     /codon_start=1
                     /product="Rfu1p"
                     /protein_id="NP_013174.1"
                     /db_xref="GI:6323102"
                     /db_xref="SGD:S000004063"
                     /db_xref="GeneID:850762"
                     /translation="MKSSKQLVQDAKDYRFNPAIPLRIYLKTCIGILEKAQCAFQAND
                     LSLSFIYYFRYVDLLTNKLSRHPELLRMDASSSSSSSYIHKREYLQLIKLEVPAVCKI
                     IESLRTQIDSQYSKLQTSLANNIAKPNINANTTPVQVEQQPLPKKSFDEYSFNQSISF
                     FQKISNAQLNTGASSQSQATARDEAYRLNYPELPRLTFST"
     gene            complement(<281956..>282456)
                     /gene="BUD20"
                     /locus_tag="YLR074C"
                     /db_xref="GeneID:850763"
     mRNA            complement(<281956..>282456)
                     /gene="BUD20"
                     /locus_tag="YLR074C"
                     /product="Bud20p"
                     /transcript_id="NM_001181961.1"
                     /db_xref="GI:296146611"
                     /db_xref="GeneID:850763"
     CDS             complement(281956..282456)
                     /gene="BUD20"
                     /locus_tag="YLR074C"
                     /note="C2H2-type zinc finger protein required for ribosome
                     assembly; shuttling factor which associates with pre-60S
                     particles in the nucleus, accompanying them to the
                     cytoplasm; cytoplasmic dissociation of Bud20p requires
                     Drg1p; N-terminus harbors a nuclear localization signal
                     (NLS) and a nuclear export signal (NES); cytoplasmic
                     Bud20p is reimported by Kap123-dependent pathway; involved
                     in bud-site selection; diploid mutants display a random
                     budding pattern; similar to human ZNF593"
                     /codon_start=1
                     /product="Bud20p"
                     /protein_id="NP_013175.1"
                     /db_xref="GI:6323103"
                     /db_xref="SGD:S000004064"
                     /db_xref="GeneID:850763"
                     /translation="MGRYSVKRYKTKRRTRDLDLIYNDLSTKESVQKLLNQPLDETKP
                     GLGQHYCIHCAKYMETAIALKTHLKGKVHKRRVKELRGVPYTQEVSDAAAGYNLNKFL
                     NRVQEITQSVGPEKESNEALLKEHLDSTLANVKTTEPTLPWAAADAEANTAAVTEAES
                     TASAST"
     gene            <282927..>283592
                     /gene="RPL10"
                     /locus_tag="YLR075W"
                     /gene_synonym="GRC5; QSR1"
                     /db_xref="GeneID:850764"
     mRNA            <282927..>283592
                     /gene="RPL10"
                     /locus_tag="YLR075W"
                     /gene_synonym="GRC5; QSR1"
                     /product="ribosomal 60S subunit protein L10"
                     /transcript_id="NM_001181962.1"
                     /db_xref="GI:296146612"
                     /db_xref="GeneID:850764"
     CDS             282927..283592
                     /gene="RPL10"
                     /locus_tag="YLR075W"
                     /gene_synonym="GRC5; QSR1"
                     /note="Ribosomal 60S subunit protein L10; responsible for
                     joining the 40S and 60S subunits; regulates translation
                     initiation; similar to members of the QM gene family;
                     homologous to mammalian ribosomal protein L10 and
                     bacterial L16; protein abundance increases in response to
                     DNA replication stress; mutations in the human ortholog
                     are associated with development of T-cell acute
                     lymphoblastic leukemia and similar changes in the yeast
                     gene result in ribosome biogenesis defects"
                     /codon_start=1
                     /product="ribosomal 60S subunit protein L10"
                     /protein_id="NP_013176.1"
                     /db_xref="GI:6323104"
                     /db_xref="SGD:S000004065"
                     /db_xref="GeneID:850764"
                     /translation="MARRPARCYRYQKNKPYPKSRYNRAVPDSKIRIYDLGKKKATVD
                     EFPLCVHLVSNELEQLSSEALEAARICANKYMTTVSGRDAFHLRVRVHPFHVLRINKM
                     LSCAGADRLQQGMRGAWGKPHGLAARVDIGQIIFSVRTKDSNKDVVVEGLRRARYKFP
                     GQQKIILSKKWGFTNLDRPEYLKKREAGEVKDDGAFVKFLSKKGSLENNIREFPEYFA
                     AQA"
     gene            <283872..>285623
                     /gene="FMP25"
                     /locus_tag="YLR077W"
                     /gene_synonym="BCA1"
                     /db_xref="GeneID:850766"
     mRNA            <283872..>285623
                     /gene="FMP25"
                     /locus_tag="YLR077W"
                     /gene_synonym="BCA1"
                     /product="Fmp25p"
                     /transcript_id="NM_001181964.1"
                     /db_xref="GI:296146613"
                     /db_xref="GeneID:850766"
     CDS             283872..285623
                     /gene="FMP25"
                     /locus_tag="YLR077W"
                     /gene_synonym="BCA1"
                     /note="Protein required for assembly of respiratory
                     complex III; mitochondrial inner membrane protein;
                     required for an early step in assembly of respiratory
                     complex III (cytochrome bc1 complex); mRNA is targeted to
                     mitochondria"
                     /codon_start=1
                     /product="Fmp25p"
                     /protein_id="NP_013178.1"
                     /db_xref="GI:6323106"
                     /db_xref="SGD:S000004067"
                     /db_xref="GeneID:850766"
                     /translation="MSFRLFTRTSQRLPRLNWVSPIRRYAKQPQYDEAELFAENINHG
                     AYKAKKRPSDEHFQWPEKSPDQITKESELQWERMAKLSAVGQGILILVVVGGLGTAYL
                     RWPELKSWWLIKMNGGRINATQEQSGQDSLEKLIRQKAKNLLREIPQVPAFQLGIDHP
                     GVYIWGRCHSKDSLFPVRVPNLDGRKFRDILLAPSDDFNTNFAIDEKGDLISWDDLGQ
                     TKTILPDQDLTSMKYSSHFLYALNKKGEILVIPIRTPDLIASQVSSRRSKLLPWKTKL
                     RYDWKLQTNQIFNGKEGEKRVVQFDAGSHHLVLLSNLGKAYCCATGNDQKQAQVSKGQ
                     FGIPTFSQFDEFPPNNQLFEIELLNKFKHEGEDVVRKREIKKIACGSYHTLAIDKTGE
                     IYAFGWNRFGQLALPISYNLEYVSFPRSVTHAFKPHFPGMTNWKCVDIHCDDETSFVT
                     IRKPGSTSDHHYFAFGNGLFGELGNNTFKNSQCDPIKIKSDDKKLTNWSCGSHCVFTE
                     TEQENEVIAWGNNDHGQLGIGKKTMKCAKPMNIPEVLKPGQDTTDLDSIYNSKLHLKK
                     EQRVVTNGNKSCLYWRV"
     gene            complement(<285736..>286559)
                     /gene="BOS1"
                     /locus_tag="YLR078C"
                     /gene_synonym="SEC32"
                     /db_xref="GeneID:850767"
     mRNA            complement(join(<285736..286467,286557..>286559))
                     /gene="BOS1"
                     /locus_tag="YLR078C"
                     /gene_synonym="SEC32"
                     /product="Bos1p"
                     /transcript_id="NM_001181965.1"
                     /db_xref="GI:296146614"
                     /db_xref="GeneID:850767"
     CDS             complement(join(285736..286467,286557..286559))
                     /gene="BOS1"
                     /locus_tag="YLR078C"
                     /gene_synonym="SEC32"
                     /note="v-SNARE (vesicle specific SNAP receptor); localized
                     to the endoplasmic reticulum membrane and necessary for
                     vesicular transport from the ER to the Golgi"
                     /codon_start=1
                     /product="Bos1p"
                     /protein_id="NP_013179.1"
                     /db_xref="GI:6323107"
                     /db_xref="SGD:S000004068"
                     /db_xref="GeneID:850767"
                     /translation="MNALYNHAVKQKNQLQQELARFEKNSVTAPISLQGSISATLVSL
                     EKTVKQYAEHLNRYKEDTNAEEIDPKFANRLATLTQDLHDFTAKFKDLKQSYNENNSR
                     TQLFGSGASHVMDSDNPFSTSETIMNKRNVGGASANGKEGSSNGGGLPLYQGLQKEQS
                     VFERGNAQLDYILEMGQQSFENIVEQNKILSKVQDRMSNGLRTLGVSEQTITSINKRV
                     FKDKLVFWIALILLIIGIYYVLKWLR"
     gene            <286820..>287674
                     /gene="SIC1"
                     /locus_tag="YLR079W"
                     /gene_synonym="SDB25"
                     /db_xref="GeneID:850768"
     mRNA            <286820..>287674
                     /gene="SIC1"
                     /locus_tag="YLR079W"
                     /gene_synonym="SDB25"
                     /product="Sic1p"
                     /transcript_id="NM_001181966.1"
                     /db_xref="GI:296146615"
                     /db_xref="GeneID:850768"
     CDS             286820..287674
                     /gene="SIC1"
                     /locus_tag="YLR079W"
                     /gene_synonym="SDB25"
                     /note="Cyclin-dependent kinase inhibitor (CKI); inhibitor
                     of Cdc28-Clb kinase complexes that controls G1/S phase
                     transition, preventing premature S phase and ensuring
                     genomic integrity; phosphorylated by Clb5/6-Cdk1 and
                     Cln1/2-Cdk1 kinase which regulate timing of Sic1p
                     degradation; phosphorylation targets Sic1p for
                     SCF(CDC4)-dependent turnover; functional homolog of
                     mammalian Kip1"
                     /codon_start=1
                     /product="Sic1p"
                     /protein_id="NP_013180.1"
                     /db_xref="GI:6323108"
                     /db_xref="SGD:S000004069"
                     /db_xref="GeneID:850768"
                     /translation="MTPSTPPRSRGTRYLAQPSGNTSSSALMQGQKTPQKPSQNLVPV
                     TPSTTKSFKNAPLLAPPNSNMGMTSPFNGLTSPQRSPFPKSSVKRTLFQFESHDNGTV
                     REEQEPLGRVNRILFPTQQNVDIDAAEEEEEGEVLLPPSRPTSARQLHLSLERDEFDQ
                     THRKKIIKDVPGTPSDKVITFELAKNWNNNSPKNDARSQESEDEEDIIINPVRVGKNP
                     FASDELVTQEIRNERKRAMLRENPDIEDVITYVNKKGEVVEKRRLTDEEKRRFKPKAL
                     FQSRDQEH"
     gene            <287916..>289250
                     /gene="EMP46"
                     /locus_tag="YLR080W"
                     /db_xref="GeneID:850769"
     mRNA            <287916..>289250
                     /gene="EMP46"
                     /locus_tag="YLR080W"
                     /product="Emp46p"
                     /transcript_id="NM_001181967.1"
                     /db_xref="GI:296146616"
                     /db_xref="GeneID:850769"
     CDS             287916..289250
                     /gene="EMP46"
                     /locus_tag="YLR080W"
                     /note="Integral membrane component of ER-derived
                     COPII-coated vesicles; functions in ER to Golgi transport;
                     EMP46 has a paralog, EMP47, that arose from the whole
                     genome duplication"
                     /codon_start=1
                     /product="Emp46p"
                     /protein_id="NP_013181.1"
                     /db_xref="GI:6323109"
                     /db_xref="SGD:S000004070"
                     /db_xref="GeneID:850769"
                     /translation="MTTRKTASSLQLLGKITGTKAGTKQKKMNFINGLIWLYMCVWMV
                     HGKVTQKDELKWNKGYSLPNLLEVTDQQKELSQWTLGDKVKLEEGRFVLTPGKNTKGS
                     LWLKPEYSIKDAMTIEWTFRSFGFRGSTKGGLAFWLKQGNEGDSTELFGGSSKKFNGL
                     MILLRLDDKLGESVTAYLNDGTKDLDIESSPYFASCLFQYQDSMVPSTLRLTYNPLDN
                     HLLKLQMDNRVCFQTRKVKFMGSSPFRIGTSAINDASKESFEILKMKLYDGVIEDSLI
                     PNVNPMGQPRVVTKVINSQTGEESFREKMPFSDKEESITSNELFEKMNKLEGKIMAND
                     IDPLLRKMNKIVENERELIQRLRPLLDLKKTAISDDSFQDFLSMNANLDRLIKEQEKI
                     RQDAKLYGKQTKGHDEIFSKISVWLALLIFIMITLAYYMFRINQDIKKVKLL"
     rep_origin      289220..289468
                     /note="ARS1212;
                     Late-firing chromosomal replication origin"
                     /db_xref="SGD:S000118472"
     gene            <290212..>291936
                     /gene="GAL2"
                     /locus_tag="YLR081W"
                     /db_xref="GeneID:850770"
     mRNA            <290212..>291936
                     /gene="GAL2"
                     /locus_tag="YLR081W"
                     /product="Gal2p"
                     /transcript_id="NM_001181968.1"
                     /db_xref="GI:296146617"
                     /db_xref="GeneID:850770"
     CDS             290212..291936
                     /gene="GAL2"
                     /locus_tag="YLR081W"
                     /note="Galactose permease; required for utilization of
                     galactose; also able to transport glucose"
                     /codon_start=1
                     /product="Gal2p"
                     /protein_id="NP_013182.1"
                     /db_xref="GI:6323110"
                     /db_xref="SGD:S000004071"
                     /db_xref="GeneID:850770"
                     /translation="MAVEENNMPVVSQQPQAGEDVISSLSKDSHLSAQSQKYSNDELK
                     AGESGSEGSQSVPIEIPKKPMSEYVTVSLLCLCVAFGGFMFGWDTGTISGFVVQTDFL
                     RRFGMKHKDGTHYLSNVRTGLIVAIFNIGCAFGGIILSKGGDMYGRKKGLSIVVSVYI
                     VGIIIQIASINKWYQYFIGRIISGLGVGGIAVLCPMLISEIAPKHLRGTLVSCYQLMI
                     TAGIFLGYCTNYGTKSYSNSVQWRVPLGLCFAWSLFMIGALTLVPESPRYLCEVNKVE
                     DAKRSIAKSNKVSPEDPAVQAELDLIMAGIEAEKLAGNASWGELFSTKTKVFQRLLMG
                     VFVQMFQQLTGNNYFFYYGTVIFKSVGLDDSFETSIVIGVVNFASTFFSLWTVENLGH
                     RKCLLLGAATMMACMVIYASVGVTRLYPHGKSQPSSKGAGNCMIVFTCFYIFCYATTW
                     APVAWVITAESFPLRVKSKCMALASASNWVWGFLIAFFTPFITSAINFYYGYVFMGCL
                     VAMFFYVFFFVPETKGLSLEEIQELWEEGVLPWKSEGWIPSSRRGNNYDLEDLQHDDK
                     PWYKAMLE"
     gene            complement(<292394..>293572)
                     /gene="SRL2"
                     /locus_tag="YLR082C"
                     /db_xref="GeneID:850771"
     mRNA            complement(<292394..>293572)
                     /gene="SRL2"
                     /locus_tag="YLR082C"
                     /product="Srl2p"
                     /transcript_id="NM_001181969.1"
                     /db_xref="GI:296146618"
                     /db_xref="GeneID:850771"
     CDS             complement(292394..293572)
                     /gene="SRL2"
                     /locus_tag="YLR082C"
                     /note="hypothetical protein; overexpression suppresses the
                     lethality caused by a rad53 null mutation"
                     /codon_start=1
                     /product="Srl2p"
                     /protein_id="NP_013183.1"
                     /db_xref="GI:6323111"
                     /db_xref="SGD:S000004072"
                     /db_xref="GeneID:850771"
                     /translation="MSNFKNFTLNSFEDYYGKPSETPKMEEEKLEVTNVNASSSKKVH
                     KSKKSTSKYDQKNVFRNSMTGIAQILPTKPVKIIEQNIDFANPKSFDLLQSTHTICFN
                     KRINTTNTKLNVETHTSSDIDNDILHVGAPTDLGGNSNDEAETRQLRKFRWSNNKEKS
                     LCEKLTVIYWALLLHTTKRASKRRPILCHQMIAEFFNRVYKEKSRVPITSRYIRDNLV
                     AWVTQGKELHEKGWVGDAKTGDLQEQFNIATVKLYESAEDGRLSIGKDKPFREENTGS
                     DSLVRAEEDSTAVTNENGHISSEKNLKKDRRESIRNQILTLDLNDEDFFQNVMKVLSA
                     IDEPELRQYVIVISELVSMEMDDGKTVREKLRDVELNINRLQVDIKEIKEMLVTLINK
                     "
     gene            complement(<294091..>296094)
                     /gene="EMP70"
                     /locus_tag="YLR083C"
                     /gene_synonym="TMN1"
                     /db_xref="GeneID:850772"
     mRNA            complement(<294091..>296094)
                     /gene="EMP70"
                     /locus_tag="YLR083C"
                     /gene_synonym="TMN1"
                     /product="Emp70p"
                     /transcript_id="NM_001181970.1"
                     /db_xref="GI:296146619"
                     /db_xref="GeneID:850772"
     CDS             complement(294091..296094)
                     /gene="EMP70"
                     /locus_tag="YLR083C"
                     /gene_synonym="TMN1"
                     /note="Protein with a role in cellular adhesion and
                     filamentous growth; also endosome-to-vacuole sorting;
                     similar to Tmn3p; member of Transmembrane Nine family of
                     proteins with 9 transmembrane segments; EMP70 has a
                     paralog, TMN2, that arose from the whole genome
                     duplication"
                     /codon_start=1
                     /product="Emp70p"
                     /protein_id="NP_013184.1"
                     /db_xref="GI:6323112"
                     /db_xref="SGD:S000004073"
                     /db_xref="GeneID:850772"
                     /translation="MIYKMAHVQLLLLYFFVSTVKAFYLPGVAPTTYRENDNIPLLVN
                     HLTPSMNYQHKDEDGNNVSGDKENFLYSYDYYYNRFHFCQPEKVEKQPESLGSVIFGD
                     RIYNSPFQLNMLQEKECESLCKTVIPGDDAKFINKLIKNGFFQNWLIDGLPAAREVYD
                     GRTKTSFYGAGFNLGFVQVTQGTDIEATPKGAETTDKDVELETRNDRNMVKTYELPYF
                     ANHFDIMIEYHDRGEGNYRVVGVIVEPVSIKRSSPGTCETTGSPLMLDEGNDNEVYFT
                     YSVKFNESATSWATRWDKYLHVYDPSIQWFSLINFSLVVVLLSSVVIHSLLRALKSDF
                     ARYNELNLDDDFQEDSGWKLNHGDVFRSPSQSLTLSILVGSGVQLFLMVTCSIFFAAL
                     GFLSPSSRGSLATVMFILYALFGFVGSYTSMGIYKFFNGPYWKANLILTPLLVPGAIL
                     LIIIALNFFLMFVHSSGVIPASTLFFMVFLWFLFSIPLSFAGSLIARKRCHWDEHPTK
                     TNQIARQIPFQPWYLKTIPATLIAGIFPFGSIAVELYFIYTSLWFNKIFYMFGFLFFS
                     FLLLTLTSSLVTILITYHSLCLENWKWQWRGFIIGGAGCALYVFIHSILFTKFKLGGF
                     TTIVLYVGYSSVISLLCCLVTGSIGFISSMLFVRKIYSSIKVD"
     gene            complement(<296589..>300251)
                     /gene="RAX2"
                     /locus_tag="YLR084C"
                     /db_xref="GeneID:850773"
     mRNA            complement(<296589..>300251)
                     /gene="RAX2"
                     /locus_tag="YLR084C"
                     /product="Rax2p"
                     /transcript_id="NM_001181971.1"
                     /db_xref="GI:296146620"
                     /db_xref="GeneID:850773"
     CDS             complement(296589..300251)
                     /gene="RAX2"
                     /locus_tag="YLR084C"
                     /note="N-glycosylated protein; involved in the maintenance
                     of bud site selection during bipolar budding; localization
                     requires Rax1p; RAX2 mRNA stability is regulated by Mpt5p"
                     /codon_start=1
                     /product="Rax2p"
                     /protein_id="NP_013185.1"
                     /db_xref="GI:6323113"
                     /db_xref="SGD:S000004074"
                     /db_xref="GeneID:850773"
                     /translation="MFVHRLWTLAFPFLVEISKASQLENIKSLLDIEDNVLPNLNISQ
                     NNSNAVQILGGVDALSFYEYTGQQNFTKEIGPETSSHGLVYYSNNTYIQLEDASDDTR
                     IDKITPFGVDSFILSGSGTINNISVGNQILYNLSTLSMTPIFNQSLGAVQAVLADNSS
                     IYFGGNFSYNNGSMTGYSALIWDSISNTTQLLPFGGFGENSSVNSIVKLNNDNILFAG
                     QFYTLDDPSALISSSNNGTNSTSSLNATTLELGQRIPLRYASWDSQGSTTFASDSLVC
                     PNTNEDAWLYPDTSGSLVCNLPYEVSPTKIRLYNSQRSDSEISVFQILTDPSSSIMNL
                     TYLDPLSGELKNCGEFCPLYSRATLLSASQNVSSSMDMITFIDNNKTDVKWTSDFQDF
                     AFVNELPVSSLKFVALNSYGGSVGLSGLELYQDTFSTYANDSLNEYGCSALTNDSSSS
                     TLSSNDWYNGLTGESYIAAKYVPDQNEPIPRVKFYPNIIHPGHYTINMYTPGCLQDNT
                     CSARGIVNVTMWNQQNNTIMKTYLIYQNNDNLKYDQIYSGYLDFSPEIVLEYVSGIYT
                     TNTATVVVADQVNVITVSLDAFNTLSDSSNAKKETLLNGILQYQKSNFTSTRLNETKV
                     GNTTLNLFPVKNYPKNSSLYADIYDNKLVIGGVSNRISIVDLNDDFEVTSSKNQTIQG
                     DVHGITKTNQGLLIFGDILSSNNQSAVFLFNGSFENVFNQSRTVNSALNISLANNDFI
                     VLDNDYVVNASSNALIRNSSSFSLSLWAAGNNGDGDVLFSGAVSHMQYGNLNGSVRFL
                     NENEIEPLNLEGGIVPYLGAYLNESATAYAYEVDSLNKIYFSNEVYPSWNWSSGITQM
                     LYADNQTLLAVSAGSSTTAELSIFDLRNLTMIANETLGSNARINALVNFEKNCSMLVG
                     GDFQMTEPNCTGLCLYNYESKTWSTFLNNTIFGEITQLSFTNSSELIISGLFETKEYQ
                     SIRLGSFNLTNSTMIPLLSGSEGKLNSFTVTEDSIVAWNDTSLFIYRNQEWNITSLPG
                     NASSISSVSAIYTDIESNTLNKRGINNVNNGSILLLNGNFNISQYGYLQSLLFDFQKW
                     TPYFISETTNTSNYNPIIFINRDVSTEFNSQSPLANVNITVTSPQSTSSQPPSSSASS
                     ESKSKSKKKKIGRGFVVLIGLALALGTVSVLGIAGVILAYVFKDPEGDYKPIKPRIDE
                     NEMLDTVPPEKLMKFV"
     gene            complement(<300673..>301989)
                     /gene="ARP6"
                     /locus_tag="YLR085C"
                     /db_xref="GeneID:850774"
     mRNA            complement(<300673..>301989)
                     /gene="ARP6"
                     /locus_tag="YLR085C"
                     /product="Arp6p"
                     /transcript_id="NM_001181972.1"
                     /db_xref="GI:296146621"
                     /db_xref="GeneID:850774"
     CDS             complement(300673..301989)
                     /gene="ARP6"
                     /locus_tag="YLR085C"
                     /note="Actin-related protein that binds nucleosomes; a
                     component of the SWR1 complex, which exchanges histone
                     variant H2AZ (Htz1p) for chromatin-bound histone H2A"
                     /codon_start=1
                     /product="Arp6p"
                     /protein_id="NP_013186.1"
                     /db_xref="GI:6323114"
                     /db_xref="SGD:S000004075"
                     /db_xref="GeneID:850774"
                     /translation="METPPIVIDNGSYEIKFGPSTNKKPFRALNALAKDKFGTSYLSN
                     HIKNIKDISSITFRRPHELGQLTLWELESCIWDYCLFNPSEFDGFDLKEGKGHHLVAS
                     ESCMTLPELSKHADQVIFEEYEFDSLFKSPVAVFVPFTKSYKGEMRTISGKDEDIDIV
                     RGNSDSTNSTSSESKNAQDSGSDYHDFQLVIDSGFNCTWIIPVLKGIPYYKAVKKLDI
                     GGRFLTGLLKETLSFRHYNMMDETILVNNIKEQCLFVSPVSYFDSFKTKDKHALEYVL
                     PDFQTSFLGYVRNPRKENVPLPEDAQIITLTDELFTIPETFFHPEISQITKPGIVEAI
                     LESLSMLPEIVRPLMVGNIVCTGGNFNLPNFAQRLAAELQRQLPTDWTCHVSVPEGDC
                     ALFGWEVMSQFAKTDSYRKARVTREEYYEHGPDWCTKHRFGYQNWI"
     gene            <302243..>306499
                     /gene="SMC4"
                     /locus_tag="YLR086W"
                     /db_xref="GeneID:850775"
     mRNA            <302243..>306499
                     /gene="SMC4"
                     /locus_tag="YLR086W"
                     /product="condensin subunit SMC4"
                     /transcript_id="NM_001181973.1"
                     /db_xref="GI:296146622"
                     /db_xref="GeneID:850775"
     CDS             302243..306499
                     /gene="SMC4"
                     /locus_tag="YLR086W"
                     /note="Subunit of the condensin complex; condensin
                     reorganizes chromosomes during both mitosis and meiosis;
                     forms a subcomplex with Smc2p that has ATP-hydrolyzing and
                     DNA-binding activity, but other condensin subunits are
                     required for chromatin binding; required for tRNA gene
                     clustering at the nucleolus; potential Cdc28p substrate"
                     /codon_start=1
                     /product="condensin subunit SMC4"
                     /protein_id="NP_013187.1"
                     /db_xref="GI:6323115"
                     /db_xref="SGD:S000004076"
                     /db_xref="GeneID:850775"
                     /translation="MSDSPLSKRQKRKSAQEPELSLDQGDAEEDSQVENRVNLSENTP
                     EPDLPALEASYSKSYTPRKLVLSSGENRYAFSQPTNSTTTSLHVPNLQPPKTSSRGRD
                     HKSYSQSPPRSPGRSPTRRLELLQLSPVKNSRVELQKIYDRHQSSSKQQSRLFINELV
                     LENFKSYAGKQVVGPFHTSFSAVVGPNGSGKSNVIDSMLFVFGFRANKMRQDRLSDLI
                     HKSEAFPSLQSCSVAVHFQYVIDESSGTSRIDEEKPGLIITRKAFKNNSSKYYINEKE
                     SSYTEVTKLLKNEGIDLDHKRFLILQGEVENIAQMKPKAEKESDDGLLEYLEDIIGTA
                     NYKPLIEERMGQIENLNEVCLEKENRFEIVDREKNSLESGKETALEFLEKEKQLTLLR
                     SKLFQFKLLQSNSKLASTLEKISSSNKDLEDEKMKFQESLKKVDEIKAQRKEIKDRIS
                     SCSSKEKTLVLERRELEGTRVSLEERTKNLVSKMEKAEKTLKSTKHSISEAENMLEEL
                     RGQQTEHETEIKDLTQLLEKERSILDDIKLSLKDKTKNISAEIIRHEKELEPWDLQLQ
                     EKESQIQLAESELSLLEETQAKLKKNVETLEEKILAKKTHKQELQDLILDLKKKLNSL
                     KDERSQGEKNFTSAHLKLKEMQKVLNAHRQRAMEARSSLSKAQNKSKVLTALSRLQKS
                     GRINGFHGRLGDLGVIDDSFDVAISTACPRLDDVVVDTVECAQHCIDYLRKNKLGYAR
                     FILLDRLRQFNLQPISTPENVPRLFDLVKPKNPKFSNAFYSVLRDTLVAQNLKQANNV
                     AYGKKRFRVVTVDGKLIDISGTMSGGGNHVAKGLMKLGTNQSDKVDDYTPEEVDKIER
                     ELSERENNFRVASDTVHEMEEELKKLRDHEPDLESQISKAEMEADSLASELTLAEQQV
                     KEAEMAYVKAVSDKAQLNVVMKNLERLRGEYNDLQSETKTKKEKIKGLQDEIMKIGGI
                     KLQMQNSKVESVCQKLDILVAKLKKVKSASKKSGGDVVKFQKLLQNSERDVELSSDEL
                     KVIEEQLKHTKLALAENDTNMNETLNLKVELKEQSEQLKEQMEDMEESINEFKSIEIE
                     MKNKLEKLNSLLTYIKSEITQQEKGLNELSIRDVTHTLGMLDDNKMDSVKEDVKNNQE
                     LDQEYRSCETQDESEIKDAETSCDNYHPMNIDETSDEVSRGIPRLSEDELRELDVELI
                     ESKINELSYYVEETNVDIGVLEEYARRLAEFKRRKLDLNNAVQKRDEVKEQLGILKKK
                     RFDEFMAGFNIISMTLKEMYQMITMGGNAELELVDSLDPFSEGVTFSVMPPKKSWRNI
                     TNLSGGEKTLSSLALVFALHKYKPTPLYVMDEIDAALDFRNVSIVANYIKERTKNAQF
                     IVISLRNNMFELAQQLVGVYKRDNRTKSTTIKNIDILNRT"
     gene            complement(<306855..>315731)
                     /gene="CSF1"
                     /locus_tag="YLR087C"
                     /db_xref="GeneID:850776"
     mRNA            complement(<306855..>315731)
                     /gene="CSF1"
                     /locus_tag="YLR087C"
                     /product="Csf1p"
                     /transcript_id="NM_001181974.1"
                     /db_xref="GI:296146623"
                     /db_xref="GeneID:850776"
     CDS             complement(306855..315731)
                     /gene="CSF1"
                     /locus_tag="YLR087C"
                     /note="Protein required for fermentation at low
                     temperature; plays a role in the maturation of secretory
                     proteins; the authentic, non-tagged protein is detected in
                     highly purified mitochondria in high-throughput studies"
                     /codon_start=1
                     /product="Csf1p"
                     /protein_id="NP_013188.1"
                     /db_xref="GI:6323116"
                     /db_xref="SGD:S000004077"
                     /db_xref="GeneID:850776"
                     /translation="MEAISQLRGVPLTHQKDFSWVFLVDWILTVVVCLTMIFYMGRIY
                     AYLVSFILEWLLWKRAKIKINVETLRVSLLGGRIHFKNLSVIHKDYTISVLEGSLTWK
                     YWLLNCRKAELIENNKSSSGKKAKLPCKISVECEGLEIFIYNRTVAYDNVINLLSKDE
                     RDKFEKYLNEHSFPEPFSDGSSADKLDEDLSESAYTTNSDASIVNDRDYQETDIGKHP
                     KLLMFLPIELKFSRGSLLLGNKFTPSVMILSYESGKGIIDVLPPKERLDLYRNKTQME
                     FKNFEISIKQNIGYDDAIGLKFKIDRGKVSKLWKTFVRVFQIVTKPVVPKKTKKSAGT
                     SDDNFYHKWKGLSLYKASAGDAKASDLDDVEFDLTNHEYAKFTSILKCPKVTIAYDVD
                     VPGVVPHGAHPTIPDIDGPDVGNNGAPPDFALDVQIHGGSICYGPWAQRQVSHLQRVL
                     SPVVSRTAKPIKKLPPGSRRIYTLFRMNISIMEDTTWRIPTRESSKDPEFLKHYKETN
                     EEYRPFGWMDLRFCKDTYANFNISVCPTVQGFQNNFHVHFLETEIRSSVNHDILLKSK
                     VFDIDGDIGYPLGWNSKAIWIINMKSEQLEAFLLREHITLVADTLSDFSAGDPTPYEL
                     FRPFVYKVNWEMEGYSIYLNVNDHNIVNNPLDFNENCYLSLHGDKLSIDVTVPRESIL
                     GTYTDMSYEISTPMFRMMLNTPPWNTLNEFMKHKEVGRAYDFTIKGSYLLYSELDIDN
                     VDTLVIECNSKSTVLHCYGFVMRYLTNVKMNYFGEFFNFVTSEEYTGVLGAREVGDVT
                     TKSSVADLASTVDSGYQNSSLKNESEDKGPMKRSDLKRTTNETDIWFTFSVWDGALIL
                     PETIYSFDPCIALHFAELVVDFRSCNYYMDIMAVLNGTSIKRHVSKQINEVFDFIRRN
                     NGADEQEHGLLSDLTIHGHRMYGLPPTEPTYFCQWDINLGDLCIDSDIEFIKGFFNSF
                     YKIGFGYNDLENILLYDTETINDMTSLTVHVEKIRIGLKDPVMKSQSVISAESILFTL
                     IDFENEKYSQRIDVKIPKLTISLNCVMGDGVDTSFLKFETKLRFTNFEQYKDIDKKRS
                     EQRRYITIHDSPYHRCPFLLPLFYQDSDTYQNLYGAIAPSSSIPTLPLPTLPDTIDYI
                     IEDIVGEYATLLETTNPFKNIFAETPSTMEPSRASFSEDDNDEEADPSSFKPVAFTED
                     RNHERDNYVVDVSYILLDVDPLLFIFAKSLLEQLYSENMVQVLDDIEIGIVKRLSNLQ
                     EGITSISNIDIHIAYLNLIWQETGEEGFELYLDRIDYQMSEKSLEKNRTNKLLEVAAL
                     AKVKTVRVTVNQKKNPDLSEDRPPALSLGIEGFEVWSSTEDRQVNSLNLTSSDITIDE
                     SQMEWLFEYCSDQGNLIQEVCTSFNSIQNTRSNSKTELISKLTAASEYYQISHDPYVI
                     TKPAFIMRLSKGHVRENRSWKIITRLRHILTYLPDDWQSNIDEVLKEKKYTSAKDAKN
                     IFMSVFSTWRNWEFSDVARSYIYGKLFTAENEKHKQNLIKKLLKCTMGSFYLTVYGEG
                     YEVEHNFVVADANLVVDLTPPVTSLPSNREETIEITGRVGSVKGKFSDRLLKLQDLIP
                     LIAAVGEDDKSDPKKELSKQFKMNTVLLVDKSELQLVMDQTKLMSRTVGGRVSLLWEN
                     LKDSTSQAGSLVIFSQKSEVWLKHTSVILGEAQLRDFSVLATTEAWSHKPTILINNQC
                     ADLHFRAMSSTEQLVTAITEIRESLMMIKERIKFKPKSKKKSQFVDQKINTVLSCYFS
                     NVSSEVMPLSPFYIRHEAKQLDIYFNKFGSNEILLSIWDTDFFMTSHQTKEQYLRFSF
                     GDIEIKGGISREGYSLINVDISISMIKLTFSEPRRIVNSFLQDEKLASQGINLLYSLK
                     PLFFSSNLPKKEKQAPSIMINWTLDTSITYFGVLVPVASTYFVFELHMLLLSLTNTNN
                     GMLPEETKVTGQFSIENILFLIKERSLPIGLSKLLDFSIKVSTLQRTVDTEQSFQVES
                     SHFRVCLSPDSLLRLMWGAHKLLDLSHYYSRRHAPNIWNTKMFTGKSDKSKEMPINFR
                     SIHILSYKFCIGWIFQYGAGSNPGLMLGYNRLFSAYEKDFGKFTVVDAFFSVANGNTS
                     STFFSEGNEKDKYNRSFLPNMQISYWFKRCGELKDWFFRFHGEALDVNFVPSFMDVIE
                     STLQSMRAFQELKKNILDVSESLRAENDNSYASTSVESASSSLAPFLDNIRSVNSNFK
                     YDGGVFRVYTYEDIETKSEPSFEIKSPVVTINCTYKHDEDKVKPHKFRTLITVDPTHN
                     TLYAGCAPLLMEFSESLQKMIKKHSTDEKPNFTKPSSQNVDYKRLLDQFDVAVKLTSA
                     KQQLSLSCEPKAKVQADVGFESFLFSMATNEFDSEQPLEFSLTLEHTKASIKHIFSRE
                     VSTSFEVGFMDLTLLFTHPDVISMYGTGLVSDLSVFFNVKQLQNLYLFLDIWRFSSIL
                     HTRPVQRTVNKEIEMSSLTSTNYADAGTEIPWCFTLIFTNVSGDVDLGPSLGMISLRT
                     QRTWLATDHYNEKRQLLHAFTDGISLTSEGRLSGLFEVANASWLSEVKWPPEKSKNTH
                     PLVSTSLNIDDIAVKAAFDYHMFLIGTISNIHFHLHNEKDAKGVLPDLLQVSFSSDEI
                     ILSSTALVVANILDIYNTIVRMRQDNKISYMETLRDSNPGESRQPILYKDILRSLKLL
                     RTDLSVNISSSKVQISPISLFDVEVLVIRIDKVSIRSETHSGKKLKTDLQLQVLDVSA
                     ALSTSKEELDEEVGASIAIDDYMHYASKIVGGTIIDIPKLAVHMTTLQEEKTNNLEYL
                     FACSFSDKISVRWNLGPVDFIKEMWTTHVKALAVRRSQVANISFGQTEEELEESIKKE
                     EAASKFNYIALEEPQIEVPQIRDLGDATPPMEWFGVNRKKFPKFTHQTAVIPVQKLVY
                     LAEKQYVKILDDTH"
     gene            <316107..>317951
                     /gene="GAA1"
                     /locus_tag="YLR088W"
                     /gene_synonym="END2"
                     /db_xref="GeneID:850777"
     mRNA            <316107..>317951
                     /gene="GAA1"
                     /locus_tag="YLR088W"
                     /gene_synonym="END2"
                     /product="Gaa1p"
                     /transcript_id="NM_001181975.1"
                     /db_xref="GI:296146624"
                     /db_xref="GeneID:850777"
     CDS             316107..317951
                     /gene="GAA1"
                     /locus_tag="YLR088W"
                     /gene_synonym="END2"
                     /note="Subunit of the GPI:protein transamidase complex;
                     removes the GPI-anchoring signal and attaches GPI
                     (glycosylphosphatidylinositol) to proteins in the ER"
                     /codon_start=1
                     /product="Gaa1p"
                     /protein_id="NP_013189.1"
                     /db_xref="GI:6323117"
                     /db_xref="SGD:S000004078"
                     /db_xref="GeneID:850777"
                     /translation="MALLEKLHRRIVDMGLVPRIIALLPVISMLCALFGFISIAILPM
                     DGQYRRTYISENALMPSQAYSYFRESEWNILRGYRSQIKEMVNMTSMERNNLMGSWLQ
                     EFGTKTAIYENEQYGETLYGVMHAPRGDGTEAMVLAVPWFNSDDEFNIGGAALGVSLA
                     RFFSRWPVWSKNIIVVFSENPRAALRSWVEAYHTSLDLTGGSIEAAVVLDYSSTEDFF
                     EYVEISYDGLNGELPNLDLVNIAISITEHEGMKVSLHGLPSDQLTNNNFWSRLKILCL
                     GIRDWALSGVKKPHGNEAFSGWRIQSVTLKAHGNSGHDITTFGRIPEAMFRSINNLLE
                     KFHQSFFFYLLLAPRQFVSISSYLPSAVALSIAFAISSLNAFINNAYANISLFSEYNL
                     VALLVWFVSLVISFVVSQAFLLIPSSGLLMTISMASCFLPLILSRKIHISEPLSYRLK
                     NVAFLYFSLVSTSLLMINFAMALLIGTLAFPMTFVKTIVESSSEHEVTTQSSNPIKTE
                     PKDEIELVENHMDTTPATPQQQKQKLKNLVLLILTNPFISITLFGLFFDDEFHGFDII
                     NKLVSAWLDLKCWSWFVLCIGWLPCWLLILASSFESKSVVVRSKEKQS"
     gene            complement(<318237..>320015)
                     /gene="ALT1"
                     /locus_tag="YLR089C"
                     /db_xref="GeneID:850778"
     mRNA            complement(<318237..>320015)
                     /gene="ALT1"
                     /locus_tag="YLR089C"
                     /product="alanine transaminase ALT1"
                     /transcript_id="NM_001181976.1"
                     /db_xref="GI:296146625"
                     /db_xref="GeneID:850778"
     CDS             complement(318237..320015)
                     /gene="ALT1"
                     /locus_tag="YLR089C"
                     /EC_number="2.6.1.2"
                     /note="Alanine transaminase (glutamic pyruvic
                     transaminase); involved in alanine biosynthesis and
                     catabolism; TOR1-independent role in determining
                     chronological lifespan; expression is induced in the
                     presence of alanine; repression is mediated by Nrg1p; ALT1
                     has a paralog, ALT2, that arose from the whole genome
                     duplication; Alt2p is catalytically inactive"
                     /codon_start=1
                     /product="alanine transaminase ALT1"
                     /protein_id="NP_013190.1"
                     /db_xref="GI:6323118"
                     /db_xref="SGD:S000004079"
                     /db_xref="GeneID:850778"
                     /translation="MLSLSAKNHFTVSNSITHVIKSYHIRTLTSSAEKMPHITTPFST
                     SASSTKLKAFRKVRPVLQRHSSSWIVAQNHRRSLSGQSSLNDLRHLNRFPHHTLKTSN
                     NEFYPAEQLTLEDVNENVLKAKYAVRGAIPMRAEELKAQLEKDPQSLPFDRIINANIG
                     NPQQLQQKPLTYYRQVLSLLQYPELLNQNEQQLVDSKLFKLDAIKRAKSLMEDIGGSV
                     GAYSSSQGVEGIRKSVAEFITKRDEGEISYPEDIFLTAGASAAVNYLLSIFCRGPETG
                     VLIPIPQYPLYTATLALNNSQALPYYLDENSGWSTNPEEIETVVKEAIQNEIKPTVLV
                     VINPGNPTGAVLSPESIAQIFEVAAKYGTVVIADEVYQENIFPGTKFHSMKKILRHLQ
                     REHPGKFDNVQLASLHSTSKGVSGECGQRGGYMELTGFSHEMRQVILKLASISLCPVV
                     TGQALVDLMVRPPVEGEESFESDQAERNSIHEKLITRAMTLYETFNSLEGIECQKPQG
                     AMYLFPKIDLPFKAVQEARHLELTPDEFYCKKLLESTGICTVPGSGFGQEPGTYHLRT
                     TFLAPGLEWIKKWESFHKEFFDQYRD"
     gene            <320701..>322080
                     /gene="XDJ1"
                     /locus_tag="YLR090W"
                     /db_xref="GeneID:850779"
     mRNA            <320701..>322080
                     /gene="XDJ1"
                     /locus_tag="YLR090W"
                     /product="Xdj1p"
                     /transcript_id="NM_001181977.1"
                     /db_xref="GI:296146626"
                     /db_xref="GeneID:850779"
     CDS             320701..322080
                     /gene="XDJ1"
                     /locus_tag="YLR090W"
                     /note="Chaperone with a role in facilitating mitochondrial
                     protein import; ascomycete-specific member of the
                     DnaJ-like family, closely related to Ydj1p; predicted to
                     be C-terminally prenylated; the authentic, non-tagged
                     protein is detected in highly purified mitochondria in
                     high-throughput studies"
                     /codon_start=1
                     /product="Xdj1p"
                     /protein_id="NP_013191.1"
                     /db_xref="GI:6323119"
                     /db_xref="SGD:S000004080"
                     /db_xref="GeneID:850779"
                     /translation="MSGSDRGDRLYDVLGVTRDATVQEIKTAYRKLALKHHPDKYVDQ
                     DSKEVNEIKFKEITAAYEILSDPEKKSHYDLYGDDNGAASSGGANGFGDEDFMNFFNN
                     FFNNGSHDGNNFPGEYDAYEEGNSTSSKDIDIDISLTLKDLYMGKKLKFDLKRQVICI
                     KCHGSGWKPKRKIHVTHDVECESCAGKGSKERLKRFGPGLVASQWVVCEKCNGKGKYT
                     KRPKNPKNFCPDCAGLGLLSKKEIITVNVAPGHHFNDVITVKGMADEEIDKTTCGDLK
                     FHLTEKQENLEQKQIFLKNFDDGAGEDLYTSITISLSEALTGFEKFLTKTFDDRLLTL
                     SVKPGRVVRPGDTIKIANEGWPILDNPHGRCGDLYVFVHIEFPPDNWFNEKSELLAIK
                     TNLPSSSSCASHATVNTEDDSNLTNNETISNFRIIHTDDLPEGIRPFKPEAQDSAHQK
                     ARSSYCCIQ"
     gene            <322297..>323178
                     /gene="GEP5"
                     /locus_tag="YLR091W"
                     /gene_synonym="RRG5"
                     /db_xref="GeneID:850780"
     mRNA            <322297..>323178
                     /gene="GEP5"
                     /locus_tag="YLR091W"
                     /gene_synonym="RRG5"
                     /product="Gep5p"
                     /transcript_id="NM_001181978.1"
                     /db_xref="GI:296146627"
                     /db_xref="GeneID:850780"
     CDS             322297..323178
                     /gene="GEP5"
                     /locus_tag="YLR091W"
                     /gene_synonym="RRG5"
                     /note="hypothetical protein; required for mitochondrial
                     genome maintenance; detected in highly purified
                     mitochondria in high-throughput studies; null mutant has
                     decreased levels of cardiolipin and
                     phosphatidylethanolamine"
                     /codon_start=1
                     /product="Gep5p"
                     /protein_id="NP_013192.1"
                     /db_xref="GI:6323120"
                     /db_xref="SGD:S000004081"
                     /db_xref="GeneID:850780"
                     /translation="MASQVNALLLPVIESTPLHQITKVALTTTLTSKQSDYKFKEIAV
                     PLTKSLQLYEKAQRRQDLRASLKALESIIYQTHFQWNNPLPRHAHLFQKHYHFLLTHW
                     PFENHRDLVDSIAVNNGKLNSTSSRSVWLKADWITLFNVKNPWVQTPPSLMRLSGTDL
                     DTFTPERIFLINSLGNHYKFLIANSHLSYNHKKYPSPGVQIPVRNALGEVSPAKQIAQ
                     LFARQLSHIYKSLFIENPPLSPENELALTAVFYDETVERRLRRLYMRACARAYTTTNA
                     DSTTEPLMFHCTRWEVD"
     gene            <323544..>326225
                     /gene="SUL2"
                     /locus_tag="YLR092W"
                     /db_xref="GeneID:850781"
     mRNA            <323544..>326225
                     /gene="SUL2"
                     /locus_tag="YLR092W"
                     /product="Sul2p"
                     /transcript_id="NM_001181979.1"
                     /db_xref="GI:296146628"
                     /db_xref="GeneID:850781"
     CDS             323544..326225
                     /gene="SUL2"
                     /locus_tag="YLR092W"
                     /note="High affinity sulfate permease; sulfate uptake is
                     mediated by specific sulfate transporters Sul1p and Sul2p,
                     which control the concentration of endogenous activated
                     sulfate intermediates"
                     /codon_start=1
                     /product="Sul2p"
                     /protein_id="NP_013193.1"
                     /db_xref="GI:6323121"
                     /db_xref="SGD:S000004082"
                     /db_xref="GeneID:850781"
                     /translation="MSREGYPNFEEVEIPDFQETNNTVPDLDDLELEYDQYKNNENND
                     TFNDKDLESNSVAKHNAVNSSKGVKGSKIDYFNPSDVSLYDNSVSQFEETTVSLKEYY
                     DHSIRSHLTVKGACSYLKSVFPIINWLPHYNFSWFTADLIAGITIGCVLVPQSMSYAQ
                     VATLPAQYGLYSSFIGAYSYSFFATSKDVCIGPVAVMSLQTAKVIADVTAKYPDGDSA
                     ITGPVIATTLALLCGIISAAVGFLRLGFLVELISLNAVAGFMTGSAFNILWGQVPALM
                     GYNSLVNTRAATYKVVIETLKHLPDTKLDAVFGLIPLFLLYVWKWWCGTYGPRLNDRY
                     NSKNPRLHKIIKWTYFYAQASRNGIIIIVFTCIGWAITRGKSKSERPISILGSVPSGL
                     KEVGVFHVPPGLMSKLGPNLPASIIVLLLEHIAISKSFGRINDYKVVPDQELIAIGVS
                     NLLGTFFNAYPATGSFSRSALKAKCNVRTPLSGLFSGSCVLLALYCLTGAFFYIPKAT
                     LSAVIIHAVSDLLASYQTTWNFWKMNPLDFICFIVTVLITVFASIEDGIYFAMCWSCA
                     MLILKVAFPAGKFLGRVEVAEVTDAYVRPDSDVVSYVSENNNGISTLEDGGEDDKESS
                     TKYVTNSSKKIETNVQTKGFDSPSSSISQPRIKYHTKWIPFDHKYTRELNPDVQILPP
                     PDGVLVYRLSESYTYLNCSRHYNIITEEVKKVTRRGQLIRHRKKSDRPWNDPGPWEAP
                     AFLKNLKFWKKRENDPESMENAPSTSVDVERDDRPLLKILCLDFSQVAQTDATALQSL
                     VDLRKAINQYADRQVEFHFVGIISPWVKRGLISRGFGTLNEEYSDESIVAGHTSYHVA
                     RVPQGEENPEKYSVYTASGTNLPFFHIDIPDFAKWDI"
     gene            complement(<326513..>327415)
                     /gene="NYV1"
                     /locus_tag="YLR093C"
                     /gene_synonym="MAM2"
                     /db_xref="GeneID:850782"
     mRNA            complement(join(<326513..327258,327400..>327415))
                     /gene="NYV1"
                     /locus_tag="YLR093C"
                     /gene_synonym="MAM2"
                     /product="Nyv1p"
                     /transcript_id="NM_001181980.1"
                     /db_xref="GI:296146629"
                     /db_xref="GeneID:850782"
     CDS             complement(join(326513..327258,327400..327415))
                     /gene="NYV1"
                     /locus_tag="YLR093C"
                     /gene_synonym="MAM2"
                     /note="v-SNARE component of the vacuolar SNARE complex;
                     involved in vesicle fusion; inhibits ATP-dependent Ca(2+)
                     transport activity of Pmc1p in the vacuolar membrane"
                     /codon_start=1
                     /product="Nyv1p"
                     /protein_id="NP_013194.2"
                     /db_xref="GI:9755337"
                     /db_xref="SGD:S000004083"
                     /db_xref="GeneID:850782"
                     /translation="MKRFNVSYVEVIKNGETISSCFQPFQKNENYGTITSANEQITPV
                     IFHNLIMDMVLPKVVPIKGNKVTKMSMNLIDGFDCFYSTDDHDPKTVYVCFTLVDMPK
                     ILPIRILSGLQEYESNATNELLSSHVGQILDSFHEELVEYRNQTLNSSGNGQSSNGNG
                     QNTISDIGDATEDQIKDVIQIMNDNIDKFLERQERVSLLVDKTSQLNSSSNKFRRKAV
                     NIKEIMWWQKVKNITLLTFTIILFVSAAFMFFYLW"
     gene            complement(<327730..>329238)
                     /gene="GIS3"
                     /locus_tag="YLR094C"
                     /db_xref="GeneID:850783"
     mRNA            complement(<327730..>329238)
                     /gene="GIS3"
                     /locus_tag="YLR094C"
                     /product="Gis3p"
                     /transcript_id="NM_001181981.1"
                     /db_xref="GI:296146630"
                     /db_xref="GeneID:850783"
     CDS             complement(327730..329238)
                     /gene="GIS3"
                     /locus_tag="YLR094C"
                     /codon_start=1
                     /product="Gis3p"
                     /protein_id="NP_013195.1"
                     /db_xref="GI:6323123"
                     /db_xref="SGD:S000004084"
                     /db_xref="GeneID:850783"
                     /translation="MLLDVNTNHTLMHDAHVHEHCLIKSIRDDGALHSWSDSSKVFYP
                     KSFYATATNKKNNKLASASMNKTATSNRTVSDEIYFHSTKPQFDGQGSAERTRTLTKR
                     NSFKRTRILKARDDSELLNENRSSLMTPSLSSVMSQVRKTNSAKTLSGECPIHEGHLT
                     QSIKRKFSEEAQSDCSSLSSSKLHPLTDDIADAVDLQTPAIGDEVLAEPVVPKMKIIN
                     INDLDLFDDWEVKDLVDIFPPVYERRPRSSSALSLVSASSDAKLRPTSVDFQIIDKKG
                     GKTSRRKSRSKSTTENMIYENDLVELEQWPSASPSPETDGSIASSELLPNKRIRQKSL
                     NTNFLKLYSIETSCKRKSILPEVEVDDHLLKQLTYSEIRSLEIKKEPNVSTNDIKLAL
                     ITRKKLWSDMVHETRNDLFGDSTPWNLHFVATTSNTEPSQGRESASEHATADLKSSLV
                     RVHSDVKPWFNNGGTMLKPCGKLNLGKVTNKTSAPTREIQYVVKGWCDSRFL"
     gene            complement(<329677..>332115)
                     /gene="IOC2"
                     /locus_tag="YLR095C"
                     /db_xref="GeneID:850784"
     mRNA            complement(<329677..>332115)
                     /gene="IOC2"
                     /locus_tag="YLR095C"
                     /product="Ioc2p"
                     /transcript_id="NM_001181982.1"
                     /db_xref="GI:296146631"
                     /db_xref="GeneID:850784"
     CDS             complement(329677..332115)
                     /gene="IOC2"
                     /locus_tag="YLR095C"
                     /note="Subunit of the Isw1b complex; exhibits
                     nucleosome-stimulated ATPase activity and acts within
                     coding regions to coordinate transcription elongation with
                     termination and processing; contains a PHD finger motif;
                     other complex members are Isw1p and Ioc4p"
                     /codon_start=1
                     /product="Ioc2p"
                     /protein_id="NP_013196.1"
                     /db_xref="GI:6323124"
                     /db_xref="SGD:S000004085"
                     /db_xref="GeneID:850784"
                     /translation="MRTKRTRGTRNVGASMPAGAANADSEDWKEYVSEDIIAQLNKHQ
                     LPYSEILDEKIADLANHWHFQYVMAWLSNVCESYTTTTFNTDQYGGSSTKCLWKNIKF
                     DEGVFVTDVFSKIDGKDSNYYNDEVDVDEGSQNLYDRIRLQLLHQLAGNKSGQLKDWN
                     VIVNHHLQNSSAYSDLVTDLPFLELEIARQFDIIYSIIKLIEMKNMIFKNYLANNLHL
                     FTFSEVILDDDNSGGEEMKSLFALPNVGVLVKKTIHRVKEGSSSQVSQTLNIPIKLQN
                     CTIKESDPDIPDSVELIHLEYSHDIDAYLQSITIDYDVITTNWGSMLEYWSENKSSKA
                     IDEFITNLIPVYAEHRLYSAKLLANREKERAIAELMTRRKRSSRLVAKEEENKKKDLE
                     SEWFEKLDEREQFIRHRNKLVSKEIKKIKDLLWNQLWQLYDQDYRDEKLTRRNELKDR
                     SGSGTPFFETSLGREEDNPLNEIDIGVLDHGPNFQSSIIPVEPPIPGTVGPLQTGDVP
                     ELPSDFCITKEELDELANYGIFTPQQEPDNQDSVFQCPGEPELAPMIITEDTETDLFN
                     NRPLICCDHCYRWQHWECQPPKIIELISSTTKSPQHTLSQRDFGVIIMGNSHGNRRSS
                     RRPQSTLEPSTKSSRPTDKRKPLSECSTFICAWCIRDLELELRNIFVPELKIIRAKQR
                     KQQEDRERRKKMKEEKKRLEELAKKRELTESVSPPVFNNAFANMSSSTTPSIAAYEKT
                     NPAINPAPNVNAAHPIITYSQQTGSKTVPQAPQAPQTSQASIQPQQQQQQQQQQQPLH
                     PKEQNFHFQFPPTN"
     gene            <332590..>336033
                     /gene="KIN2"
                     /locus_tag="YLR096W"
                     /db_xref="GeneID:850785"
     mRNA            <332590..>336033
                     /gene="KIN2"
                     /locus_tag="YLR096W"
                     /product="Kin2p"
                     /transcript_id="NM_001181983.1"
                     /db_xref="GI:296146632"
                     /db_xref="GeneID:850785"
     CDS             332590..336033
                     /gene="KIN2"
                     /locus_tag="YLR096W"
                     /EC_number="2.7.11.1"
                     /note="Serine/threonine protein kinase involved in
                     regulation of exocytosis; localizes to the cytoplasmic
                     face of the plasma membrane; KIN2 has a paralog, KIN1,
                     that arose from the whole genome duplication"
                     /codon_start=1
                     /product="Kin2p"
                     /protein_id="NP_013197.1"
                     /db_xref="GI:6323125"
                     /db_xref="SGD:S000004086"
                     /db_xref="GeneID:850785"
                     /translation="MPNPNTADYLVNPNFRTSKGGSLSPTPEAFNDTRVAAPATLRMM
                     GKQSGPRNDQQQAPLMPPADIKQGKEQAAQRQNDASRPNGAVELRQFHRRSLGDWEFL
                     ETVGAGSMGKVKLVKHRQTKEICVIKIVNRASKAYLHKQHSLPSPKNESEILERQKRL
                     EKEIARDKRTVREASLGQILYHPHICRLFEMCTMSNHFYMLFEYVSGGQLLDYIIQHG
                     SLKEHHARKFARGIASALQYLHANNIVHRDLKIENIMISSSGEIKIIDFGLSNIFDYR
                     KQLHTFCGSLYFAAPELLKAQPYTGPEVDIWSFGIVLYVLVCGKVPFDDENSSILHEK
                     IKKGKVDYPSHLSIEVISLLTRMIVVDPLRRATLKNVVEHPWMNRGYDFKAPSYVPNR
                     VPLTPEMIDSQVLKEMYRLEFIDDIEDTRRSLIRLVTEKEYIQLSQEYWDKLSNAKGL
                     SSSLNNNYLNSTAQQTLIQNHITSNPSQSGYNEPDSNFEDPTLAYHPLLSIYHLVSEM
                     VARKLAKLQRRQALALQAQAQQRQQQQQVALGTKVALNNNSPDIMTKMRSPQKEVVPN
                     PGIFQVPAIGTSGTSNNTNTSNKPPLHVMVPPKLTIPEQAHTSPTSRKSSDIHTELNG
                     VLKSTPVPVSGEYQQRSASPVVGEHQEKNTIGGIFRRISQSGQSQHPTRQQEPLPERE
                     PPTYMSKSNEISIKVPKSHSRTISDYIPSARRYPSYVPNSVDVKQKPAKNTTIAPPIR
                     SVSQKQNSDLPALPQNAELIVQKQRQKLLQENLDKLQINDNDNNNVNAVVDGINNDNS
                     DHYLSVPKGRKLHPSARAKSVGHARRESLKFTRPPIPAALPPSDMTNDNGFLGEANKE
                     RYNPVSSNFSTVPEDSTTYSNDTNNRLTSVYSQELTEKQILEEASKAPPGSMPSIDYP
                     KSMFLKGFFSVQTTSSKPLPIVRHNIISVLTRMNIDFKEVKGGFICVQQRPSIETAAV
                     PVITTTGVGLDSGKAMDLQNSLDSQLSSSYHSTASSASRNSSIKRQGSYKRGQNNIPL
                     TPLATNTHQRNSSIPMSPNYGNQSNGTSGELSSMSLDYVQQQDDILTTSRAQNINNVN
                     GQTEQTNTSGIKERPPIKFEIHIVKVRIVGLAGVHFKKVSGNTWLYKELASYILKELN
                     L"
     gene            complement(<336231..>337265)
                     /gene="HRT3"
                     /locus_tag="YLR097C"
                     /db_xref="GeneID:850786"
     mRNA            complement(<336231..>337265)
                     /gene="HRT3"
                     /locus_tag="YLR097C"
                     /product="SCF ubiquitin ligase complex subunit HRT3"
                     /transcript_id="NM_001181984.1"
                     /db_xref="GI:296146633"
                     /db_xref="GeneID:850786"
     CDS             complement(336231..337265)
                     /gene="HRT3"
                     /locus_tag="YLR097C"
                     /note="Putative SCF-ubiquitin ligase F-box protein; based
                     on both genetic and physical interactions and sequence
                     similarity; identified in association with Cdc53p, Skp1p
                     and Ubi4 in large and small-scale studies"
                     /codon_start=1
                     /product="SCF ubiquitin ligase complex subunit HRT3"
                     /protein_id="NP_013198.1"
                     /db_xref="GI:6323126"
                     /db_xref="SGD:S000004087"
                     /db_xref="GeneID:850786"
                     /translation="MIVDYEKDPRAKEAIAIWEKGVLKEKDGSMSDAINFYRSALKIH
                     DNVESLYRKKILDEWMLHKKLSGLSMTTDAPDEQNETGKDDLSVEENAELQPCWILEI
                     LPDDILLRIIKKVILMSGESWVNLSMTCSTFSKLCFHDSVPFKTFAKYIYSKQIYDKM
                     AMDLNGITDINTFEKEIWRGDDYRMLRERPYIKFEGVYISVVNYVRYGSNAESSLSLL
                     KPVHMITYYRYFRFYENGQCLRLLSTDEPSAVVKHFSKENKPRHSHMCYWSLGFDYDF
                     GHLKITRSDEKYTFIEEFQIKNQGNKRYQRLKWLSSIVVDKEGNASNCSLRNEKSFFF
                     SRVKSFKDPG"
     gene            complement(<337527..>339473)
                     /gene="CHA4"
                     /locus_tag="YLR098C"
                     /gene_synonym="SIL2; SIL3"
                     /db_xref="GeneID:850787"
     mRNA            complement(<337527..>339473)
                     /gene="CHA4"
                     /locus_tag="YLR098C"
                     /gene_synonym="SIL2; SIL3"
                     /product="Cha4p"
                     /transcript_id="NM_001181985.1"
                     /db_xref="GI:296146634"
                     /db_xref="GeneID:850787"
     CDS             complement(337527..339473)
                     /gene="CHA4"
                     /locus_tag="YLR098C"
                     /gene_synonym="SIL2; SIL3"
                     /note="DNA binding transcriptional activator; mediates
                     serine/threonine activation of the catabolic L-serine
                     (L-threonine) deaminase (CHA1); Zinc-finger protein with
                     Zn[2]-Cys[6] fungal-type binuclear cluster domain"
                     /codon_start=1
                     /product="Cha4p"
                     /protein_id="NP_013199.1"
                     /db_xref="GI:6323127"
                     /db_xref="SGD:S000004088"
                     /db_xref="GeneID:850787"
                     /translation="MMLEPSPPPLTTTVTPSLPSSLKKSVTDNDQNNNNVPRKRKLAC
                     QNCRRRRRKCNMEKPCSNCIKFRTECVFTQQDLRNKRYSTTYVEALQSQIRSLKEQLQ
                     ILSSSSSTIASNALSSLKNNSDHGDAPNEKILKYGETAQSALPSSESNDENESDAFTK
                     KMPSESPPPVGTNSIYPSNSLSIIKKKTDGSTRYQQQQVSLKNLSRSPLILRSLSLFF
                     KWLYPGHYLFIHRETFLSAFFGDTNTKSYYCSEELVFAIAALGSLISYKSETELFQQS
                     EVFYQRAKTIVLKKIFQLEDSSLAESSSSSKLAIIQTLLCLAFYDIGSGENPMAWYLS
                     GLAFRIAHEIGLHLNPEAWSNVYEDELSIMDFEVRSRIYWGCYIADHLIAILFGRSTS
                     LRLSNSTVPETDELPEIETGIEEYIYDPKVILSTANPLKKLIVLSRITEIFASKIFSP
                     NETLLQRSEYLAKFNLEVYNWRRDLPPELQWTKRSLMEMTDFNPTIAYVWFHYYIVLI
                     SYNKPFIYEIKQSRELVEGYVDELYYLLKVWKNKFKTFEKATIYMIYSAILAIQCMKS
                     NLIKKDRKQDFLNFLSAPTLNYELARKFIENSEDALHNSETMDLLGTLSHGNDFALEY
                     NFDFTLLNEIDMLIGGNTNDGLSK"
     gene            complement(<339744..>340928)
                     /gene="ICT1"
                     /locus_tag="YLR099C"
                     /db_xref="GeneID:850788"
     mRNA            complement(<339744..>340928)
                     /gene="ICT1"
                     /locus_tag="YLR099C"
                     /product="lysophosphatidic acid acyltransferase ICT1"
                     /transcript_id="NM_001181986.1"
                     /db_xref="GI:296146635"
                     /db_xref="GeneID:850788"
     CDS             complement(339744..340928)
                     /gene="ICT1"
                     /locus_tag="YLR099C"
                     /EC_number="2.3.1.51"
                     /note="Lysophosphatidic acid acyltransferase; responsible
                     for enhanced phospholipid synthesis during organic solvent
                     stress; null displays increased sensitivity to Calcofluor
                     white; highly expressed during organic solvent stress;
                     ICT1 has a paralog, ECM18, that arose from the whole
                     genome duplication"
                     /codon_start=1
                     /product="lysophosphatidic acid acyltransferase ICT1"
                     /protein_id="NP_013200.1"
                     /db_xref="GI:6323128"
                     /db_xref="SGD:S000004089"
                     /db_xref="GeneID:850788"
                     /translation="MWTNTFKWCSKTEKETTTADAKVCASVQGLKALQQQIMDSTTVR
                     GSVNNTMTPGGINQWHFHNKRANKVCTPTVLIHGYAASSMAFYRTFENLSDNIKDLYA
                     IDLPANGASEAPALQVNKTKKIKSLRFKHIEDDVVIPVIEKRPPAEDIKSHLEQYESY
                     FVDRIEQWRKDNKLRKINVVGHSFGGYISFKYALKYPDSIEKLCLISPLGVENSIHAI
                     THKWEPNTTYPLTFTDPSSRYYTRKLNVPRFIFENQLNVLKWMGPIGSKLCSNYISTA
                     YVKVPDQIYKDYLLHSFVGKNQTVQPQTIKVFTHLFERNLIARDPIINNVRFLNPATP
                     VMFMYGEHDWMDKYAGYLTTESMLKNKAKASYVEVPDAGHNLFLDNPQHFASSLVSFL
                     SK"
     gene            <341325..>341588
                     /gene="MIM2"
                     /locus_tag="YLR099W-A"
                     /db_xref="GeneID:850789"
     mRNA            <341325..>341588
                     /gene="MIM2"
                     /locus_tag="YLR099W-A"
                     /product="Mim2p"
                     /transcript_id="NM_001184484.1"
                     /db_xref="GI:296146636"
                     /db_xref="GeneID:850789"
     CDS             341325..341588
                     /gene="MIM2"
                     /locus_tag="YLR099W-A"
                     /note="Mitochondrial protein required for outer membrane
                     protein import; involved in import of the subset of
                     proteins with multiple alpha-helical transmembrane
                     segments, including Ugo1p, Tom20p, and Fzo1p; component of
                     a large protein complex in the outer membrane that
                     includes Mim1p; not essential in W303 strain background"
                     /codon_start=1
                     /product="Mim2p"
                     /protein_id="NP_076901.1"
                     /db_xref="GI:13129179"
                     /db_xref="SGD:S000007618"
                     /db_xref="GeneID:850789"
                     /translation="MADSEDTSVILQGIDTINSVEGLEEDGYLSDEDTSLSNELADAQ
                     RQWEESLQQLNKLLNWVLLPLLGKYIGRRMAKTLWSRFIEHFV"
     gene            <341810..>342853
                     /gene="ERG27"
                     /locus_tag="YLR100W"
                     /db_xref="GeneID:850790"
     mRNA            <341810..>342853
                     /gene="ERG27"
                     /locus_tag="YLR100W"
                     /product="3-keto-steroid reductase"
                     /transcript_id="NM_001181987.1"
                     /db_xref="GI:296146637"
                     /db_xref="GeneID:850790"
     CDS             341810..342853
                     /gene="ERG27"
                     /locus_tag="YLR100W"
                     /EC_number="1.1.1.270"
                     /note="3-keto sterol reductase; catalyzes the last of
                     three steps required to remove two C-4 methyl groups from
                     an intermediate in ergosterol biosynthesis; mutants are
                     sterol auxotrophs"
                     /codon_start=1
                     /product="3-keto-steroid reductase"
                     /protein_id="NP_013201.1"
                     /db_xref="GI:6323129"
                     /db_xref="SGD:S000004090"
                     /db_xref="GeneID:850790"
                     /translation="MNRKVAIVTGTNSNLGLNIVFRLIETEDTNVRLTIVVTSRTLPR
                     VQEVINQIKDFYNKSGRVEDLEIDFDYLLVDFTNMVSVLNAYYDINKKYRAINYLFVN
                     AAQGIFDGIDWIGAVKEVFTNPLEAVTNPTYKIQLVGVKSKDDMGLIFQANVFGPYYF
                     ISKILPQLTRGKAYIVWISSIMSDPKYLSLNDIELLKTNASYEGSKRLVDLLHLATYK
                     DLKKLGINQYVVQPGIFTSHSFSEYLNFFTYFGMLCLFYLARLLGSPWHNIDGYKAAN
                     APVYVTRLANPNFEKQDVKYGSATSRDGMPYIKTQEIDPTGMSDVFAYIQKKKLEWDE
                     KLKDQIVETRTPI"
     gene            complement(<342970..>343767)
                     /gene="APC9"
                     /locus_tag="YLR102C"
                     /db_xref="GeneID:850792"
     mRNA            complement(<342970..>343767)
                     /gene="APC9"
                     /locus_tag="YLR102C"
                     /product="anaphase promoting complex subunit 9"
                     /transcript_id="NM_001181989.1"
                     /db_xref="GI:296146638"
                     /db_xref="GeneID:850792"
     CDS             complement(342970..343767)
                     /gene="APC9"
                     /locus_tag="YLR102C"
                     /note="Subunit of the Anaphase-Promoting Complex/Cyclosome
                     (APC/C); APC/C is a ubiquitin-protein ligase required for
                     degradation of anaphase inhibitors, including mitotic
                     cyclins, during the metaphase/anaphase transition"
                     /codon_start=1
                     /product="anaphase promoting complex subunit 9"
                     /protein_id="NP_013203.1"
                     /db_xref="GI:6323131"
                     /db_xref="SGD:S000004092"
                     /db_xref="GeneID:850792"
                     /translation="MNQNGDKNEGKLFQLPSLPPWKTPRFNKANFNNFTTPLRKRSTR
                     VINDDSMPITGEVLEERTADDLYGINMDVDEVDYLNTLSHIEEEKQYDYSPFCERNTL
                     RESRIDSFLKAERAAHCLVFHKVGHLDGIDSYRPDIDIMCGEEANKYDSANPEGNGSM
                     LLESVPGCNKEDLERLSRREFVTNSKPNMRRLDDIINHETNALKSFWNDSGLVNSLQS
                     HHLHEEYLLLQEELKNVYKIKCHDRVPIESLRDKCRRHYSNEDSSFL"
     gene            complement(<343989..>345941)
                     /gene="CDC45"
                     /locus_tag="YLR103C"
                     /gene_synonym="SLD4"
                     /db_xref="GeneID:850793"
     mRNA            complement(<343989..>345941)
                     /gene="CDC45"
                     /locus_tag="YLR103C"
                     /gene_synonym="SLD4"
                     /product="Cdc45p"
                     /transcript_id="NM_001181990.1"
                     /db_xref="GI:296146639"
                     /db_xref="GeneID:850793"
     CDS             complement(343989..345941)
                     /gene="CDC45"
                     /locus_tag="YLR103C"
                     /gene_synonym="SLD4"
                     /note="DNA replication initiation factor; recruited to MCM
                     pre-RC complexes at replication origins; promotes release
                     of MCM from Mcm10p, recruits elongation machinery; binds
                     tightly to ssDNA, which disrupts interaction with the MCM
                     helicase and stalls it during replication stress; mutants
                     in human homolog may cause velocardiofacial and DiGeorge
                     syndromes"
                     /codon_start=1
                     /product="Cdc45p"
                     /protein_id="NP_013204.1"
                     /db_xref="GI:6323132"
                     /db_xref="SGD:S000004093"
                     /db_xref="GeneID:850793"
                     /translation="MYYGISQFSEAYNKILRNSSSHSSCQLVIFVSCLNIDALCATKM
                     LSLLFKKQLVQSQIVPIFGYSELRRHYSQLDDNINSLLLVGFGGVIDLEAFLEIDPQE
                     YVIDTDEKSGEQSFRRDIYVLDAHRPWNLDNIFGSQIIQCFDDGTVDDTLGEQKEAYY
                     KLLELDEESGDDELSGDENDNNGGDDEATDADEVTDEDEEDEDETISNKRGNSSIGPN
                     DLSKRKQRKKQIHEYEGVLEEYYSQGTTVVNSISAQIYSLLSAIGETNLSNLWLNILG
                     TTSLDIAYAQVYNRLYPLLQDEVKRLTPSSRNSVKTPDTLTLNIQPDYYLFLLRHSSL
                     YDSFYYSNYVNAKLSLWNENGKKRLHKMFARMGIPLSTAQETWLYMDHSIKRELGIIF
                     DKNLDRYGLQDIIRDGFVRTLGYRGSISASEFVEALTALLEVGNSTDKDSVKINNDNN
                     DDTDGEEEEDNSAQKLTNLRKRWVSNFWLSWDALDDRKVELLNRGIQLAQDLQRAIFN
                     TGVAILEKKLIKHLRIYRLCVLQDGPDLDLYRNPLTLLRLGNWLIECCAESEDKQLLP
                     MVLASIDENTDTYLVAGLTPRYPRGLDTIHTKKPILNNFSMAFQQITAETDAKVRIDN
                     FESSIIEIRREDLSPFLEKLTLSGLL"
     gene            <346585..>346980
                     /gene="LCL2"
                     /locus_tag="YLR104W"
                     /db_xref="GeneID:850794"
     mRNA            <346585..>346980
                     /gene="LCL2"
                     /locus_tag="YLR104W"
                     /product="Lcl2p"
                     /transcript_id="NM_001181991.1"
                     /db_xref="GI:296146640"
                     /db_xref="GeneID:850794"
     CDS             346585..346980
                     /gene="LCL2"
                     /locus_tag="YLR104W"
                     /note="hypothetical protein; mutant is deficient in
                     amounts of cell wall mannosylphosphate and has long
                     chronological lifespan; genetic interactions suggest a
                     role in ER-associated protein degradation (ERAD)"
                     /codon_start=1
                     /product="Lcl2p"
                     /protein_id="NP_013205.1"
                     /db_xref="GI:6323133"
                     /db_xref="SGD:S000004094"
                     /db_xref="GeneID:850794"
                     /translation="MSQSRWSIVLIFALFIFGSTGVNAFFNFGHHQQQQQQQQQSYED
                     QVLNNPCDGYLCPDTLTCVAQQKDCPCPFPKSQLKCVLPDNKFVCISKPATHNEKFRA
                     IYDDPVKGPKAKNKGFRDCGWVSDAYKNH"
     gene            complement(<347047..>348180)
                     /gene="SEN2"
                     /locus_tag="YLR105C"
                     /db_xref="GeneID:850795"
     mRNA            complement(<347047..>348180)
                     /gene="SEN2"
                     /locus_tag="YLR105C"
                     /product="Sen2p"
                     /transcript_id="NM_001181992.1"
                     /db_xref="GI:296146641"
                     /db_xref="GeneID:850795"
     CDS             complement(347047..348180)
                     /gene="SEN2"
                     /locus_tag="YLR105C"
                     /EC_number="4.6.1.16"
                     /note="Subunit of the tRNA splicing endonuclease; tRNA
                     splicing endonuclease is composed of Sen2p, Sen15p,
                     Sen34p, and Sen54p; Sen2p contains the active site for
                     tRNA 5' splice site cleavage and has similarity to Sen34p
                     and to Archaeal tRNA splicing endonuclease"
                     /codon_start=1
                     /product="Sen2p"
                     /protein_id="NP_013206.1"
                     /db_xref="GI:6323134"
                     /db_xref="SGD:S000004095"
                     /db_xref="GeneID:850795"
                     /translation="MSKGRVNQKRYKYPLPIHPVDDLPELILHNPLSWLYWAYRYYKS
                     TNALNDKVHVDFIGDTTLHITVQDDKQMLYLWNNGFFGTGQFSRSEPTWKARTEARLG
                     LNDTPLHNRGGTKSNTETEMTLEKVTQQRRLQRLEFKKERAKLERELLELRKKGGHID
                     EENILLEKQRESLRKFKLKQTEDVGIVAQQQDISESNLRDEDNNLLDENGDLLPLESL
                     ELMPVEAMFLTFALPVLDISPACLAGKLFQFDAKYKDIHSFVRSYVIYHHYRSHGWCV
                     RSGIKFGCDYLLYKRGPPFQHAEFCVMGLDHDVSKDYTWYSSIARVVGGAKKTFVLCY
                     VERLISEQEAIALWKSNNFTKLFNSFQVGEVLYKRWVPGRNRD"
     gene            complement(348427..348510)
                     /locus_tag="snR79"
                     /db_xref="GeneID:9164937"
     ncRNA           complement(348427..348510)
                     /locus_tag="snR79"
                     /ncRNA_class="snoRNA"
                     /product="SNR79"
                     /note="C/D box small nucleolar RNA (snoRNA); guides
                     2'-O-methylation of small subunit (SSU) rRNA at position
                     C1007"
                     /db_xref="SGD:S000007313"
                     /db_xref="GeneID:9164937"
     gene            complement(<349006..>363738)
                     /gene="MDN1"
                     /locus_tag="YLR106C"
                     /gene_synonym="REA1"
                     /db_xref="GeneID:850796"
     mRNA            complement(<349006..>363738)
                     /gene="MDN1"
                     /locus_tag="YLR106C"
                     /gene_synonym="REA1"
                     /product="AAA family ATPase midasin"
                     /transcript_id="NM_001181993.1"
                     /db_xref="GI:296146642"
                     /db_xref="GeneID:850796"
     CDS             complement(349006..363738)
                     /gene="MDN1"
                     /locus_tag="YLR106C"
                     /gene_synonym="REA1"
                     /note="Huge dynein-related AAA-type ATPase (midasin);
                     forms extended pre-60S particle with the Rix1 complex
                     (Rix1p-Ipi1p-Ipi3p); acts in removal of ribosomal
                     biogenesis factors at successive steps of pre-60S assembly
                     and export from nucleus"
                     /codon_start=1
                     /product="AAA family ATPase midasin"
                     /protein_id="NP_013207.1"
                     /db_xref="GI:6323135"
                     /db_xref="SGD:S000004096"
                     /db_xref="GeneID:850796"
                     /translation="MSQDRILLDLDVVNQRLILFNSAFPSDAIEAPFHFSNKESTSEN
                     LDNLAGTILHSRSITGHVFLYKHIFLEIVARWIKDSKKKDYVLVIEKLASIITIFPVA
                     MPLIEDYLDKENDHFITILQNPSTQKDSDMFKILLAYYRLLYHNKEVFARFIQPDILY
                     QLVDLLTKEQENQVVIFLALKVLSLYLDMGEKTLNDMLDTYIKSRDSLLGHFEGDSGI
                     DYSFLELNEAKRCANFSKLPSVPECFTIEKKSSYFIIEPQDLSTKVASICGVIVPKVH
                     TIHDKVFYPLTFVPTHKTVSSLRQLGRKIQNSTPIMLIGKAGSGKTFLINELSKYMGC
                     HDSIVKIHLGEQTDAKLLIGTYTSGDKPGTFEWRAGVLATAVKEGRWVLIEDIDKAPT
                     DVLSILLSLLEKRELTIPSRGETVKAANGFQLISTVRINEDHQKDSSNKIYNLNMIGM
                     RIWNVIELEEPSEEDLTHILAQKFPILTNLIPKLIDSYKNVKSIYMNTKFISLNKGAH
                     TRVVSVRDLIKLCERLDILFKNNGINKPDQLIQSSVYDSIFSEAADCFAGAIGEFKAL
                     EPIIQAIGESLDIASSRISLFLTQHVPTLENLDDSIKIGRAVLLKEKLNIQKKSMNST
                     LFAFTNHSLRLMEQISVCIQMTEPVLLVGETGTGKTTVVQQLAKMLAKKLTVINVSQQ
                     TETGDLLGGYKPVNSKTVAVPIQENFETLFNATFSLKKNEKFHKMLHRCFNKNQWKNV
                     VKLWNEAYKMAQSILKITNTENENENAKKKKRRLNTHEKKLLLDKWADFNDSVKKFEA
                     QSSSIENSFVFNFVEGSLVKTIRAGEWLLLDEVNLATADTLESISDLLTEPDSRSILL
                     SEKGDAEPIKAHPDFRIFACMNPATDVGKRDLPMGIRSRFTEIYVHSPERDITDLLSI
                     IDKYIGKYSVSDEWVGNDIAELYLEAKKLSDNNTIVDGSNQKPHFSIRTLTRTLLYVT
                     DIIHIYGLRRSLYDGFCMSFLTLLDQKSEAILKPVIEKFTLGRLKNVKSIMSQTPPSP
                     GPDYVQFKHYWMKKGPNTIQEQAHYIITPFVEKNMMNLVRATSGKRFPVLIQGPTSSG
                     KTSMIKYLADITGHKFVRINNHEHTDLQEYLGTYVTDDTGKLSFKEGVLVEALRKGYW
                     IVLDELNLAPTDVLEALNRLLDDNRELFIPETQEVVHPHPDFLLFATQNPPGIYGGRK
                     ILSRAFRNRFLELHFDDIPQDELEIILRERCQIAPSYAKKIVEVYRQLSIERSASRLF
                     EQKNSFATLRDLFRWALRDAVGYEQLAASGYMLLAERCRTPQEKVTVKKTLEKVMKVK
                     LDMDQYYASLEDKSLEAIGSVTWTKGMRRLSVLVSSCLKNKEPVLLVGETGCGKTTIC
                     QLLAQFMGRELITLNAHQNTETGDILGAQRPVRNRSEIQYKLIKSLKTALNIANDQDV
                     DLKELLQLYSKSDNKNIAEDVQLEIQKLRDSLNVLFEWSDGPLIQAMRTGNFFLLDEI
                     SLADDSVLERLNSVLEPERSLLLAEQGSSDSLVTASENFQFFATMNPGGDYGKKELSP
                     ALRNRFTEIWVPSMEDFNDVNMIVSSRLLEDLKDLANPIVKFSEWFGKKLGGGNATSG
                     VISLRDILAWVEFINKVFPKIQNKSTALIQGASMVFIDALGTNNTAYLAENENDLKSL
                     RTECIIQLLKLCGDDLELQQIETNEIIVTQDELQVGMFKIPRFPDAQSSSFNLTAPTT
                     ASNLVRVVRAMQVHKPILLEGSPGVGKTSLITALANITGNKLTRINLSEQTDLVDLFG
                     ADAPGERSGEFLWHDAPFLRAMKKGEWVLLDEMNLASQSVLEGLNACLDHRGEAYIPE
                     LDISFSCHPNFLVFAAQNPQYQGGGRKGLPKSFVNRFSVVFIDMLTSDDLLLIAKHLY
                     PSIEPDIIAKMIKLMSTLEDQVCKRKLWGNSGSPWEFNLRDTLRWLKLLNQYSICEDV
                     DVFDFVDIIVKQRFRTISDKNKAQLLIEDIFGKFSTKENFFKLTEDYVQINNEVALRN
                     PHYRYPITQNLFPLECNVAVYESVLKAINNNWPLVLVGPSNSGKTETIRFLASILGPR
                     VDVFSMNSDIDSMDILGGYEQVDLTRQISYITEELTNIVREIISMNMKLSPNATAIME
                     GLNLLKYLLNNIVTPEKFQDFRNRFNRFFSHLEGHPLLKTMSMNIEKMTEIITKEASV
                     KFEWFDGMLVKAVEKGHWLILDNANLCSPSVLDRLNSLLEIDGSLLINECSQEDGQPR
                     VLKPHPNFRLFLTMDPKYGELSRAMRNRGVEIYIDELHSRSTAFDRLTLGFELGENID
                     FVSIDDGIKKIKLNEPDMSIPLKHYVPSYLSRPCIFAQVHDILLLSDEEPIEESLAAV
                     IPISHLGEVGKWANNVLNCTEYSEKKIAERLYVFITFLTDMGVLEKINNLYKPANLKF
                     QKALGLHDKQLTEETVSLTLNEYVLPTVSKYSDKIKSPESLYLLSSLRLLLNSLNALK
                     LINEKSTHGKIDELTYIELSAAAFNGRHLKNIPRIPIFCILYNILTVMSENLKTESLF
                     CGSNQYQYYWDLLVIVIAALETAVTKDEARLRVYKELIDSWIASVKSKSDIEITPFLN
                     INLEFTDVLQLSRGHSITLLWDIFRKNYPTTSNSWLAFEKLINLSEKFDKVRLLQFSE
                     SYNSIKDLMDVFRLLNDDVLNNKLSEFNLLLSKLEDGINELELISNKFLNKRKHYFAD
                     EFDNLIRYTFSVDTAELIKELAPASSLATQKLTKLITNKYNYPPIFDVLWTEKNAKLT
                     SFTSTIFSSQFLEDVVRKSNNLKSFSGNQIKQSISDAELLLSSTIKCSPNLLKSQMEY
                     YKNMLLSWLRKVIDIHVGGDCLKLTLKELCSLIEEKTASETRVTFAEYIFPALDLAES
                     SKSLEELGEAWITFGTGLLLLFVPDSPYDPAIHDYVLYDLFLKTKTFSQNLMKSWRNV
                     RKVISGDEEIFTEKLINTISDDDAPQSPRVYRTGMSIDSLFDEWMAFLSSTMSSRQIK
                     ELVSSYKCNSDQSDRRLEMLQQNSAHFLNRLESGYSKFADLNDILAGYIYSINFGFDL
                     LKLQKSKDRASFQISPLWSMDPINISCAENVLSAYHELSRFFKKGDMEDTSIEKVLMY
                     FLTLFKFHKRDTNLLEIFEAALYTLYSRWSVRRFRQEQEENEKSNMFKFNDNSDDYEA
                     DFRKLFPDYEDTALVTNEKDISSPENLDDIYFKLADTYISVFDKDHDANFSSELKSGA
                     IITTILSEDLKNTRIEELKSGSLSAVINTLDAETQSFKNTEVFGNIDFYHDFSIPEFQ
                     KAGDIIETVLKSVLKLLKQWPEHATLKELYRVSQEFLNYPIKTPLARQLQKIEQIYTY
                     LAEWEKYASSEVSLNNTVKLITDLIVSWRKLELRTWKGLFNSEDAKTRKSIGKWWFYL
                     YESIVISNFVSEKKETAPNATLLVSSLNLFFSKSTLGEFNARLDLVKAFYKHIQLIGL
                     RSSKIAGLLHNTIKFYYQFKPLIDERITNGKKSLEKEIDDIILLASWKDVNVDALKQS
                     SRKSHNNLYKIVRKYRDLLNGDAKTIIEAGLLYSNENKLKLPTLKQHFYEDPNLEASK
                     NLVKEISTWSMRAAPLRNIDTVASNMDSYLEKISSQEFPNFADLASDFYAEAERLRKE
                     TPNVYTKENKKRLAYLKTQKSKLLGDALKELRRIGLKVNFREDIQKVQSSTTTILANI
                     APFNNEYLNSSDAFFFKILDLLPKLRSAASNPSDDIPVAAIERGMALAQSLMFSLITV
                     RHPLSEFTNDYCKINGMMLDLEHFTCLKGDIVHSSLKANVDNVRLFEKWLPSLLDYAA
                     QTLSVISKYSATSEQQKILLDAKSTLSSFFVHFNSSRIFDSSFIESYSRFELFINELL
                     KKLENAKETGNAFVFDIIIEWIKANKGGPIKKEQKRGPSVEDVEQAFRRTFTSIILSF
                     QKVIGDGIESISETDDNWLSASFKKVMVNVKLLRSSVVSKNIETALSLLKDFDFTTTE
                     SIYVKSVISFTLPVITRYYNAMTVVLERSRIYYTNTSRGMYILSTILHSLAKNGFCSP
                     QPPSEEVDDKNLQEGTGLGDGEGAQNNNKDVEQDEDLTEDAQNENKEQQDKDERDDEN
                     EDDAVEMEGDMAGELEDLSNGEENDDEDTDSEEEELDEEIDDLNEDDPNAIDDKMWDD
                     KASDNSKEKDTDQNLDGKNQEEDVQAAENDEQQRDNKEGGDEDPNAPEDGDEEIENDE
                     NAEEENDVGEQEDEVKDEEGEDLEANVPEIETLDLPEDMNLDSEHEESDEDVDMSDGM
                     PDDLNKEEVGNEDEEVKQESGIESDNENDEPGPEEDAGETETALDEEEGAEEDVDMTN
                     DEGKEDEENGPEEQAMSDEEELKQDAAMEENKEKGGEQNTEGLDGVEEKADTEDIDQE
                     AAVQQDSGSKGAGADATDTQEQDDVGGSGTTQNTYEEDQEDVTKNNEESREEATAALK
                     QLGDSMKEYHRRRQDIKEAQTNGEEDENLEKNNERPDEFEHVEGANTETDTQALGSAT
                     QDQLQTIDEDMAIDDDREEQEVDQKELVEDADDEKMDIDEEEMLSDIDAHDANNDVDS
                     KKSGFIGKRKSEEDFENELSNEHFSADQEDDSEIQSLIENIEDNPPDASASLTPERSL
                     EESRELWHKSEISTADLVSRLGEQLRLILEPTLATKLKGDYKTGKRLNMKRIIPYIAS
                     QFRKDKIWLRRTKPSKRQYQIMIALDDSKSMSESKCVKLAFDSLCLVSKTLTQLEAGG
                     LSIVKFGENIKEVHSFDQQFSNESGARAFQWFGFQETKTDVKKLVAESTKIFERARAM
                     VHNDQWQLEIVISDGICEDHETIQKLVRRARENKIMLVFVIIDGITSNESILDMSQVN
                     YIPDQYGNPQLKITKYLDTFPFEFYVVVHDISELPEMLSLILRQYFTDLASS"
     gene            <364116..>365330
                     /gene="REX3"
                     /locus_tag="YLR107W"
                     /db_xref="GeneID:850797"
     mRNA            <364116..>365330
                     /gene="REX3"
                     /locus_tag="YLR107W"
                     /product="Rex3p"
                     /transcript_id="NM_001181994.1"
                     /db_xref="GI:296146643"
                     /db_xref="GeneID:850797"
     CDS             364116..365330
                     /gene="REX3"
                     /locus_tag="YLR107W"
                     /EC_number="3.1.-.-"
                     /note="RNA exonuclease; required for maturation of the RNA
                     component of RNase MRP; functions redundantly with Rnh70p
                     and Rex2p in processing of U5 snRNA and RNase P RNA;
                     member of RNase D family of exonucleases"
                     /codon_start=1
                     /product="Rex3p"
                     /protein_id="NP_013208.1"
                     /db_xref="GI:6323136"
                     /db_xref="SGD:S000004097"
                     /db_xref="GeneID:850797"
                     /translation="MGSLLRPVDLVNQPLGFQERYKILQKLFKQLQKAYAHTKGTNID
                     LERLATRLEVHVAKNSLSGQSYKFNMSILLRDVLKYKGDLSKIKINGRPLKGAKPHLS
                     SIGNANSITTKSKAMEALKALILDSKVLEKNGYIVKEMQNKTNDDNSTQLYAPCLRCS
                     SNFKKTDIMEKTLCRYHPLKRIYNRDTKNHQYPCCGETTDSVSFLRLGCKTFFHHVFR
                     GESYDELCKISKFSSTDDIDGVENVLSLDCEMAFTSLGYEMIRLTIVDFFTGKTLFDH
                     VIQPIGDIVDLNSDFSGVHEIDRTNCPTYKEALDVFLSENLINKNSILIGHGLENDLN
                     VMRLFHNKVIDTAILYSRTKFKVSLKNLAFEVLSRKIQNGEHDSSQDAIATMDVVKVK
                     IGISPSQNKWEK"
     LTR             complement(365810..366144)
                     /note="Ty1 LTR"
                     /db_xref="SGD:S000007067"
     gene            366235..366346
                     /locus_tag="snR6"
                     /db_xref="GeneID:9164922"
     ncRNA           366235..366346
                     /locus_tag="snR6"
                     /ncRNA_class="snRNA"
                     /product="SNR6"
                     /note="U6 spliceosomal RNA (U6 snRNA); mediates catalysis
                     of pre-mRNA splicing by the spliceosome; interacts with
                     U4; homology to U6 snRNA, interacts with snr14"
                     /db_xref="SGD:S000006494"
                     /db_xref="GeneID:9164922"
     gene            complement(<366667..>368124)
                     /locus_tag="YLR108C"
                     /db_xref="GeneID:850798"
     mRNA            complement(<366667..>368124)
                     /locus_tag="YLR108C"
                     /product="hypothetical protein"
                     /transcript_id="NM_001181995.1"
                     /db_xref="GI:296146644"
                     /db_xref="GeneID:850798"
     CDS             complement(366667..368124)
                     /locus_tag="YLR108C"
                     /note="hypothetical protein; green fluorescent protein
                     (GFP)-fusion protein localizes to the nucleus; YLR108C is
                     not an esssential gene; protein abundance increases in
                     response to DNA replication stress; YLR108C has a paralog,
                     YDR132C, that arose from the whole genome duplication"
                     /codon_start=1
                     /product="hypothetical protein"
                     /protein_id="NP_013209.1"
                     /db_xref="GI:6323137"
                     /db_xref="SGD:S000004098"
                     /db_xref="GeneID:850798"
                     /translation="MSGQKGEIVVYTKELETTPELLPNHEVFKIRIGQKLFEISGATL
                     NSDAPNFFTQFFNTHDKNTILFVDRSEDVFIIIYRHLQGYFPDIKNEVQFTCLFADAL
                     YFQLPKLVKLIKEYDYHFTNIGGVPFKVPKSLFHEEGNRLNYFETISRISYEEIEKWE
                     SNKKPGFPPLLPPSYIARSPEFFRDILSLLGGSKLELSEERTASLIKECRYYRLNRLE
                     QELVRAKIIYNPLTNCQEVCIALDSVSKKGVTIERLTSLHTGNQSLAVSSCLNGTEGE
                     KAATGFHKTETDSGNNDEYEPPTKKVKHCIERHWSMLKYQRPYIDTVSHDLIFQLHSN
                     QCKIIFNKKNKTVHVDLSREAAVLFENKFSDVLLENPDFKIDLSEYKVKLRDSQMQVE
                     SHLIIPACVSICDLTVNGAKCCNIFSLVNDSKCKGRVLDCTNLKVLNCVHGLKLHLSK
                     SMWKLGTNNGRIILVAVKAETFSGTKEYCKMIDFL"
     gene            <368781..>369311
                     /gene="AHP1"
                     /locus_tag="YLR109W"
                     /db_xref="GeneID:850799"
     mRNA            <368781..>369311
                     /gene="AHP1"
                     /locus_tag="YLR109W"
                     /product="Ahp1p"
                     /transcript_id="NM_001181996.1"
                     /db_xref="GI:296146645"
                     /db_xref="GeneID:850799"
     CDS             368781..369311
                     /gene="AHP1"
                     /locus_tag="YLR109W"
                     /EC_number="1.11.1.15"
                     /note="Thiol-specific peroxiredoxin; reduces
                     hydroperoxides to protect against oxidative damage;
                     function in vivo requires covalent conjugation to Urm1p"
                     /codon_start=1
                     /product="Ahp1p"
                     /protein_id="NP_013210.1"
                     /db_xref="GI:6323138"
                     /db_xref="SGD:S000004099"
                     /db_xref="GeneID:850799"
                     /translation="MSDLVNKKFPAGDYKFQYIAISQSDADSESCKMPQTVEWSKLIS
                     ENKKVIITGAPAAFSPTCTVSHIPGYINYLDELVKEKEVDQVIVVTVDNPFANQAWAK
                     SLGVKDTTHIKFASDPGCAFTKSIGFELAVGDGVYWSGRWAMVVENGIVTYAAKETNP
                     GTDVTVSSVESVLAHL"
     gene            complement(<369697..>370098)
                     /gene="CCW12"
                     /locus_tag="YLR110C"
                     /db_xref="GeneID:850800"
     mRNA            complement(<369697..>370098)
                     /gene="CCW12"
                     /locus_tag="YLR110C"
                     /product="Ccw12p"
                     /transcript_id="NM_001181997.1"
                     /db_xref="GI:296146646"
                     /db_xref="GeneID:850800"
     CDS             complement(369697..370098)
                     /gene="CCW12"
                     /locus_tag="YLR110C"
                     /note="Cell wall mannoprotein; plays a role in maintenance
                     of newly synthesized areas of cell wall; localizes to
                     periphery of small buds, septum region of larger buds, and
                     shmoo tip; CCW12 has a paralog, YDR134C, that arose from
                     the whole genome duplication"
                     /codon_start=1
                     /product="Ccw12p"
                     /protein_id="NP_013211.1"
                     /db_xref="GI:6323139"
                     /db_xref="SGD:S000004100"
                     /db_xref="GeneID:850800"
                     /translation="MQFSTVASIAAVAAVASAAANVTTATVSQESTTLVTITSCEDHV
                     CSETVSPALVSTATVTVDDVITQYTTWCPLTTEAPKNGTSTAAPVTSTEAPKNTTSAA
                     PTHSVTSYTGAAAKALPAAGALLAGAAALLL"
     gene            <371620..>372927
                     /gene="HOG1"
                     /locus_tag="YLR113W"
                     /gene_synonym="SSK3"
                     /db_xref="GeneID:850803"
     mRNA            <371620..>372927
                     /gene="HOG1"
                     /locus_tag="YLR113W"
                     /gene_synonym="SSK3"
                     /product="mitogen-activated protein kinase HOG1"
                     /transcript_id="NM_001182000.1"
                     /db_xref="GI:296146647"
                     /db_xref="GeneID:850803"
     CDS             371620..372927
                     /gene="HOG1"
                     /locus_tag="YLR113W"
                     /gene_synonym="SSK3"
                     /EC_number="2.7.11.24"
                     /note="Mitogen-activated protein kinase involved in
                     osmoregulation; controls global reallocation of RNAPII in
                     osmotic shock; activates CDC28 by stimulating antisense
                     RNA transcription; mediates recruitment/activation of
                     RNAPII at Hot1p-dependent promoters; with Mrc1p defines
                     novel S-phase checkpoint that prevent conflicts between
                     DNA replication and transcription; nuclear form represses
                     pseudohyphal growth; autophosphorylates; protein abundance
                     increases under DNA replication stress"
                     /codon_start=1
                     /product="mitogen-activated protein kinase HOG1"
                     /protein_id="NP_013214.1"
                     /db_xref="GI:6323142"
                     /db_xref="SGD:S000004103"
                     /db_xref="GeneID:850803"
                     /translation="MTTNEEFIRTQIFGTVFEITNRYNDLNPVGMGAFGLVCSATDTL
                     TSQPVAIKKIMKPFSTAVLAKRTYRELKLLKHLRHENLICLQDIFLSPLEDIYFVTEL
                     QGTDLHRLLQTRPLEKQFVQYFLYQILRGLKYVHSAGVIHRDLKPSNILINENCDLKI
                     CDFGLARIQDPQMTGYVSTRYYRAPEIMLTWQKYDVEVDIWSAGCIFAEMIEGKPLFP
                     GKDHVHQFSIITDLLGSPPKDVINTICSENTLKFVTSLPHRDPIPFSERFKTVEPDAV
                     DLLEKMLVFDPKKRITAADALAHPYSAPYHDPTDEPVADAKFDWHFNDADLPVDTWRV
                     MMYSEILDFHKIGGSDGQIDISATFDDQVAAATAAAAQAQAQAQAQVQLNMAAHSHNG
                     AGTTGNDHSDIAGGNKVSDHVAANDTITDYGNQAIQYANEFQQ"
     rep_origin      373156..373399
                     /note="ARS1213;
                     Autonomously Replicating Sequence"
                     /db_xref="SGD:S000118473"
     LTR             373999..374338
                     /note="Ty3 LTR"
                     /db_xref="SGD:S000007095"
     gene            374355..374427
                     /locus_tag="tR(ACG)L"
                     /db_xref="GeneID:850804"
     tRNA            374355..374427
                     /locus_tag="tR(ACG)L"
                     /product="tRNA-Arg"
                     /note="Arginine tRNA (tRNA-Arg), predicted by tRNAscan-SE
                     analysis; one of 6 nuclear tRNA genes containing the
                     tDNA-anticodon ACG (converted to ICG in the mature tRNA),
                     decodes CGU, CGC, and probably CGA codons into arginine,
                     one of 19 nuclear tRNAs for arginine"
                     /db_xref="SGD:S000006704"
                     /db_xref="GeneID:850804"
     gene            complement(<374944..>377238)
                     /gene="AVL9"
                     /locus_tag="YLR114C"
                     /db_xref="GeneID:850805"
     mRNA            complement(<374944..>377238)
                     /gene="AVL9"
                     /locus_tag="YLR114C"
                     /product="Avl9p"
                     /transcript_id="NM_001182001.1"
                     /db_xref="GI:296146648"
                     /db_xref="GeneID:850805"
     CDS             complement(374944..377238)
                     /gene="AVL9"
                     /locus_tag="YLR114C"
                     /note="Conserved protein involved in exocytic transport
                     from the Golgi; mutation is synthetically lethal with apl2
                     vps1 double mutation; member of a protein superfamily with
                     orthologs in diverse organisms; relocalizes from bud neck
                     to cytoplasm upon DNA replication stress"
                     /codon_start=1
                     /product="Avl9p"
                     /protein_id="NP_013215.1"
                     /db_xref="GI:6323143"
                     /db_xref="SGD:S000004104"
                     /db_xref="GeneID:850805"
                     /translation="MDEHEEAVIFGICLVDFHHKRGPEIEYWYGLPEGTQSAELWPNL
                     PFQALPDGSHSFEETFTYFTLLYDERRQRSPPNGATDLSDDSINDNTTLFAISCSRQI
                     KSDELVTKDKDVTRSTVQKAIVVISRQPIFGQIKDKLSIVTNAFFLQHDFGDRKIIQS
                     LYENLKSIYTPASLVRNAENRLYIGLCLRKILHDFKRNALVLLKAIMLEKKIIVYGND
                     VEALCNLQFGLISLIPDLMSNLQDSGSPQLFQDISKLNVVDSFKSSNRESVLRFLGFP
                     LPIFEKGGLFSPYTPLQQMNDIRSERTLFFMIGSSNTLLAEQKEELCHIFVNTDNSTV
                     DILDKTLNPVLQLSSHDKKWIESISGIVSDTWNENDDETPKNSQFEGSEDFIRWQFED
                     YLTGLLSSVKLSDYLDLHKENDQALKTIPEDMLNSNPVHLFNLNWVQSWKETQNFLIF
                     NSRTDDRLFDLFPPKHIYNGADTLSLLQQRFLATFHNLKRSSSNSSSNKNGHQSEEDI
                     KDQESIESKKSVSQISVNPGKNTDKPAANLWNSWKEYFNKPKNTANEDVTESTEDLKN
                     RSKTSNAIQKAMMGLGLHYKPDAETDQQSEEVGNSEDNEDDDTDEDSEDDDDDGGDDD
                     DSEDDDDDDDGEGDENGDDGEGDENGDDGEGDENGDKEDSQDFSNGFTDVTNINTDHD
                     KENEQNFEGNAENFNEDETVADKDIEGGPESNKNSDSKTDIYENDRNVEDSSKTRNTV
                     KKSNEEGGANDAAIGNCVQDEEKL"
     gene            <377985..>380564
                     /gene="CFT2"
                     /locus_tag="YLR115W"
                     /gene_synonym="YDH1"
                     /db_xref="GeneID:850806"
     mRNA            <377985..>380564
                     /gene="CFT2"
                     /locus_tag="YLR115W"
                     /gene_synonym="YDH1"
                     /product="Cft2p"
                     /transcript_id="NM_001182002.1"
                     /db_xref="GI:296146649"
                     /db_xref="GeneID:850806"
     CDS             377985..380564
                     /gene="CFT2"
                     /locus_tag="YLR115W"
                     /gene_synonym="YDH1"
                     /note="Subunit of the mRNA cleavage and polyadenlylation
                     factor (CPF); required for pre-mRNA cleavage,
                     polyadenylation and poly(A) site recognition, 43%
                     similarity with the mammalian CPSF-100 protein."
                     /codon_start=1
                     /product="Cft2p"
                     /protein_id="NP_013216.1"
                     /db_xref="GI:6323144"
                     /db_xref="SGD:S000004105"
                     /db_xref="GeneID:850806"
                     /translation="MTYKYNCCDDGSGTTVGSVVRFDNVTLLIDPGWNPSKVSYEQCI
                     KYWEKVIPEIDVIILSQPTIECLGAHSLLYYNFTSHFISRIQVYATLPVINLGRVSTI
                     DSYASAGVIGPYDTNKLDLEDIEISFDHIVPLKYSQLVDLRSRYDGLTLLAYNAGVCP
                     GGSIWCISTYSEKLVYAKRWNHTRDNILNAASILDATGKPLSTLMRPSAIITTLDRFG
                     SSQPFKKRSKIFKDTLKKGLSSDGSVIIPVDMSGKFLDLFTQVHELLFESTKINAHTQ
                     VPVLILSYARGRTLTYAKSMLEWLSPSLLKTWENRNNTSPFEIGSRIKIIAPNELSKY
                     PGSKICFVSEVGALINEVIIKVGNSEKTTLILTKPSFECASSLDKILEIVEQDERNWK
                     TFPEDGKSFLCDNYISIDTIKEEPLSKEETEAFKVQLKEKKRDRNKKILLVKRESKKL
                     ANGNAIIDDTNGERAMRNQDILVENVNGVPPIDHIMGGDEDDDEEEENDNLLNLLKDN
                     SEKSAAKKNTEVPVDIIIQPSAASKHKMFPFNPAKIKKDDYGTVVDFTMFLPDDSDNV
                     NQNSRKRPLKDGAKTTSPVNEEDNKNEEEDGYNMSDPISKRSKHRASRYSGFSGTGEA
                     ENFDNLDYLKIDKTLSKRTISTVNVQLKCSVVILNLQSLVDQRSASIIWPSLKSRKIV
                     LSAPKQIQNEEITAKLIKKNIEVVNMPLNKIVEFSTTIKTLDISIDSNLDNLLKWQRI
                     SDSYTVATVVGRLVKESLPQVNNHQKTASRSKLVLKPLHGSSRSHKTGALSIGDVRLA
                     QLKKLLTEKNYIAEFKGEGTLVINEKVAVRKINDAETIIDGTPSELFDTVKKLVTDML
                     AKI"
     gene            <380822..>382252
                     /gene="MSL5"
                     /locus_tag="YLR116W"
                     /db_xref="GeneID:850807"
     mRNA            <380822..>382252
                     /gene="MSL5"
                     /locus_tag="YLR116W"
                     /product="Msl5p"
                     /transcript_id="NM_001182003.1"
                     /db_xref="GI:296146650"
                     /db_xref="GeneID:850807"
     CDS             380822..382252
                     /gene="MSL5"
                     /locus_tag="YLR116W"
                     /note="Component of commitment complex; which defines
                     first step in splicing pathway; essential protein that
                     interacts with Mud2p and Prp40p, forming a bridge between
                     the intron ends; also involved in nuclear retention of
                     pre-mRNA; relocalizes to the cytosol in response to
                     hypoxia"
                     /codon_start=1
                     /product="Msl5p"
                     /protein_id="NP_013217.1"
                     /db_xref="GI:6323145"
                     /db_xref="SGD:S000004106"
                     /db_xref="GeneID:850807"
                     /translation="MSFRRINSRYFENRKGSSMEEKKAKVPPNVNLSLWRKNTVESDV
                     HRFNSLPSKISGALTREQIYSYQVMFRIQEITIKLRTNDFVPPSRKNRSPSPPPVYDA
                     QGKRTNTREQRYRKKLEDERIKLVEIALKTIPYFVPPDDYKRPTKFQDKYYIPVDQYP
                     DVNFVGLLLGPRGRTLRKLQEDSNCKIAIRGRGSVKEGKNASDLPPGAMNFEDPLHCL
                     IIADSEDKIQKGIKVCQNIVIKAVTSPEGQNDLKRGQLRELAELNGTLREDNRPCPIC
                     GLKDHKRYDCPNRKIPNIQGIVCKICGQTGHFSRDCNSSSQRMSRFDRNATVNNSAPI
                     QSNDVHYNSNTHPIQAPKRSRYDNNSTEPPLKFPASSRYAPSPSPPASHISRQAQNVT
                     PTPPPGLTSSSFSSGVPGIAPPPLQSPPESEQPKFSLPPPPGMTTVQSSIAPPPGLSG
                     PPGFSNNMGNDINKPTPPGLQGPPGL"
     gene            complement(<382471..>384534)
                     /gene="CLF1"
                     /locus_tag="YLR117C"
                     /gene_synonym="NTC77; SYF3"
                     /db_xref="GeneID:850808"
     mRNA            complement(<382471..>384534)
                     /gene="CLF1"
                     /locus_tag="YLR117C"
                     /gene_synonym="NTC77; SYF3"
                     /product="Clf1p"
                     /transcript_id="NM_001182004.1"
                     /db_xref="GI:296146651"
                     /db_xref="GeneID:850808"
     CDS             complement(382471..384534)
                     /gene="CLF1"
                     /locus_tag="YLR117C"
                     /gene_synonym="NTC77; SYF3"
                     /note="Member of the NineTeen Complex (NTC); this complex
                     contains Prp19p and stabilizes U6 snRNA in catalytic forms
                     of the spliceosome containing U2, U5, and U6 snRNAs;
                     homolog of Drosophila crooked neck protein; interacts with
                     U1 snRNP proteins"
                     /codon_start=1
                     /product="Clf1p"
                     /protein_id="NP_013218.1"
                     /db_xref="GI:6323146"
                     /db_xref="SGD:S000004107"
                     /db_xref="GeneID:850808"
                     /translation="MDTLEPTAVDTHVSAEQILRDVYKKGQKARGSTNIDILDLEELR
                     EYQRRKRTEYEGYLKRNRLDMGQWIRYAQFEIEQHDMRRARSIFERALLVDSSFIPLW
                     IRYIDAELKVKCINHARNLMNRAISTLPRVDKLWYKYLIVEESLNNVEIVRSLYTKWC
                     SLEPGVNAWNSFVDFEIRQKNWNGVREIYSKYVMAHPQMQTWLKWVRFENRHGNTEFT
                     RSVYSLAIDTVANLQNLQIWSDMEVAKLVNSFAHWEAAQQEYERSSALYQIAIEKWPS
                     NQLLKAGLLDFEKQFGDINSIEETISYKRKMEYETILSNNAYDYDTWWLYLDLISESF
                     PKQIMQTFEKAIVDSRPKELSKNVQWKRYIYLWMRYICYVELELENSLLEEELFQRLI
                     DDIIPHKHFTFSKIWLMYAKFLIRHDDVPKARKILGKAIGLCPKAKTFKGYIELEVKL
                     KEFDRVRKIYEKFIEFQPSDLQIWSQYGELEENLGDWDRVRGIYTIALDENSDFLTKE
                     AKIVLLQKYITFETESQEFEKARKLYRRYLELNQYSPQSWIEFAMYQTSTPTEQQLLD
                     LAKLQSENVDEDIEFEITDENKLEARKVFEEAIVFFKEKDDKQGRLSILEALKDYEET
                     YGTELDQETVKKRFPKVIKKVRLQNGVEEEFVDYIFPDDIDDDKPKPSKFLELAKKWK
                     QEQAL"
     rep_origin      384534..384725
                     /note="ARS1214;
                     Putative replication origin; identified in multiple array
                     studies, not yet confirmed by plasmid-based assay"
                     /db_xref="SGD:S000130182"
     gene            complement(<384725..>385408)
                     /locus_tag="YLR118C"
                     /gene_synonym="APT1"
                     /db_xref="GeneID:850809"
     mRNA            complement(<384725..>385408)
                     /locus_tag="YLR118C"
                     /gene_synonym="APT1"
                     /product="palmitoyl-(protein) hydrolase"
                     /transcript_id="NM_001182005.1"
                     /db_xref="GI:296146652"
                     /db_xref="GeneID:850809"
     CDS             complement(384725..385408)
                     /locus_tag="YLR118C"
                     /gene_synonym="APT1"
                     /EC_number="3.1.2.-"
                     /note="Acyl-protein thioesterase responsible for
                     depalmitoylation of Gpa1p; green fluorescent protein
                     (GFP)-fusion protein localizes to both the cytoplasm and
                     nucleus and is induced in response to the DNA-damaging
                     agent MMS"
                     /codon_start=1
                     /product="palmitoyl-(protein) hydrolase"
                     /protein_id="NP_013219.1"
                     /db_xref="GI:6323147"
                     /db_xref="SGD:S000004108"
                     /db_xref="GeneID:850809"
                     /translation="MNGLRVAAKIQPARQTIIFLHGLGDTGSGWGFLAQYLQQRDPAA
                     FQHTNFVFPNAPELHVTANGGALMPAWFDILEWDPSFSKVDSDGFMNSLNSIEKTVKQ
                     EIDKGIKPEQIIIGGFSQGAALALATSVTLPWKIGGIVALSGFCSIPGILKQHKNGIN
                     VKTPIFHGHGDMDPVVPIGLGIKAKQFYQDSCEIQNYEFKVYKGMAHSTVPDELEDLA
                     SFIKKSLSS"
     gene            <385534..>386175
                     /gene="SRN2"
                     /locus_tag="YLR119W"
                     /gene_synonym="SRN10; VPL16; VPS37"
                     /db_xref="GeneID:850810"
     mRNA            <385534..>386175
                     /gene="SRN2"
                     /locus_tag="YLR119W"
                     /gene_synonym="SRN10; VPL16; VPS37"
                     /product="ESCRT-I subunit protein SRN2"
                     /transcript_id="NM_001182006.1"
                     /db_xref="GI:296146653"
                     /db_xref="GeneID:850810"
     CDS             385534..386175
                     /gene="SRN2"
                     /locus_tag="YLR119W"
                     /gene_synonym="SRN10; VPL16; VPS37"
                     /note="Component of the ESCRT-I complex; ESCRT-I is
                     involved in ubiquitin-dependent sorting of proteins into
                     the endosome; suppressor of rna1-1 mutation; may be
                     involved in RNA export from nucleus"
                     /codon_start=1
                     /product="ESCRT-I subunit protein SRN2"
                     /protein_id="NP_013220.1"
                     /db_xref="GI:6323148"
                     /db_xref="SGD:S000004109"
                     /db_xref="GeneID:850810"
                     /translation="MKVKATKLRIKQRRKNKGLNISRLDIIRAEMDVVPSPGLPEKVN
                     EKSKNIPLPEGINLLSSKEIIDLIQTHRHQLELYVTKFNPLTDFAGKIHAFRDQFKQL
                     EENFEDLHEQKDKVQALLENCRILESKYVASWQDYHSEFSKKYGDIALKKKLEQNTKK
                     LDEESSQLETTTRSIDSADDLDQFIKNYLDIRTQYHLRREKLATWDKQGNLKY"
     gene            complement(<386511..>388220)
                     /gene="YPS1"
                     /locus_tag="YLR120C"
                     /gene_synonym="YAP3"
                     /db_xref="GeneID:850811"
     mRNA            complement(<386511..>388220)
                     /gene="YPS1"
                     /locus_tag="YLR120C"
                     /gene_synonym="YAP3"
                     /product="Yps1p"
                     /transcript_id="NM_001182007.1"
                     /db_xref="GI:296146654"
                     /db_xref="GeneID:850811"
     CDS             complement(386511..388220)
                     /gene="YPS1"
                     /locus_tag="YLR120C"
                     /gene_synonym="YAP3"
                     /EC_number="3.4.23.41"
                     /note="Aspartic protease; member of the yapsin family of
                     proteases involved in cell wall growth and maintenance;
                     attached to the plasma membrane via a
                     glycosylphosphatidylinositol (GPI) anchor; YPS1 has a
                     paralog, MKC7, that arose from the whole genome
                     duplication"
                     /codon_start=1
                     /product="Yps1p"
                     /protein_id="NP_013221.1"
                     /db_xref="GI:6323149"
                     /db_xref="SGD:S000004110"
                     /db_xref="GeneID:850811"
                     /translation="MKLKTVRSAVLSSLFASQVLGKIIPAANKRDDDSNSKFVKLPFH
                     KLYGDSLENVGSDKKPEVRLLKRADGYEEIIITNQQSFYSVDLEVGTPPQNVTVLVDT
                     GSSDLWIMGSDNPYCSSNSMGSSRRRVIDKRDDSSSGGSLINDINPFGWLTGTGSAIG
                     PTATGLGGGSGTATQSVPASEATMDCQQYGTFSTSGSSTFRSNNTYFSISYGDGTFAS
                     GTFGTDVLDLSDLNVTGLSFAVANETNSTMGVLGIGLPELEVTYSGSTASHSGKAYKY
                     DNFPIVLKNSGAIKSNTYSLYLNDSDAMHGTILFGAVDHSKYTGTLYTIPIVNTLSAS
                     GFSSPIQFDVTINGIGISDSGSSNKTLTTTKIPALLDSGTTLTYLPQTVVSMIATELG
                     AQYSSRIGYYVLDCPSDDSMEIVFDFGGFHINAPLSSFILSTGTTCLLGIIPTSDDTG
                     TILGDSFLTNAYVVYDLENLEISMAQARYNTTSENIEIITSSVPSAVKAPGYTNTWST
                     SASIVTGGNIFTVNSSQTASFSGNLTTSTASATSTSSKRNVGDHIVPSLPLTLISLLF
                     AFI"
     gene            complement(<388744..>390270)
                     /gene="YPS3"
                     /locus_tag="YLR121C"
                     /gene_synonym="YPS4"
                     /db_xref="GeneID:850812"
     mRNA            complement(<388744..>390270)
                     /gene="YPS3"
                     /locus_tag="YLR121C"
                     /gene_synonym="YPS4"
                     /product="Yps3p"
                     /transcript_id="NM_001182008.1"
                     /db_xref="GI:296146655"
                     /db_xref="GeneID:850812"
     CDS             complement(388744..390270)
                     /gene="YPS3"
                     /locus_tag="YLR121C"
                     /gene_synonym="YPS4"
                     /EC_number="3.4.23.-"
                     /note="Aspartic protease; member of the yapsin family of
                     proteases involved in cell wall growth and maintenance;
                     attached to the plasma membrane via a
                     glycosylphosphatidylinositol (GPI) anchor"
                     /codon_start=1
                     /product="Yps3p"
                     /protein_id="NP_013222.1"
                     /db_xref="GI:6323150"
                     /db_xref="SGD:S000004111"
                     /db_xref="GeneID:850812"
                     /translation="MKLQLAAVATLAVLTSPAFGRVLPDGKYVKIPFTKKKNGDNGEL
                     SKRSNGHEKFVLANEQSFYSVELAIGTPSQNLTVLLDTGSADLWVPGKGNPYCGSVMD
                     CDQYGVFDKTKSSTFKANKSSPFYAAYGDGTYAEGAFGQDKLKYNELDLSGLSFAVAN
                     ESNSTFGVLGIGLSTLEVTYSGKVAIMDKRSYEYDNFPLFLKHSGAIDATAYSLFLND
                     ESQSSGSILFGAVDHSKYEGQLYTIPLVNLYKSQGYQHPVAFDVTLQGLGLQTDKRNI
                     TLTTTKLPALLDSGTTLTYLPSQAVALLAKSLNASYSKTLGYYEYTCPSSDNKTSVAF
                     DFGGFRINAPLSDFTMQTSVGTCVLAIIPQAGNATAILGDSFLRNAYVVYDLDNYEIS
                     LAQAKYGTGKENVEVIKSTVPSAIRAPSYNNTWSNYASATSGGNIFTTVRTFNGTSTA
                     TTTRSTTTKKTNSTTTAKSTHKSKRALQRAATNSASSIRSTLGLLLVPSLLILSVFFS
                     "
     gene            <393484..>393894
                     /locus_tag="YLR125W"
                     /db_xref="GeneID:850816"
     mRNA            <393484..>393894
                     /locus_tag="YLR125W"
                     /product="hypothetical protein"
                     /transcript_id="NM_001182012.1"
                     /db_xref="GI:296146656"
                     /db_xref="GeneID:850816"
     CDS             393484..393894
                     /locus_tag="YLR125W"
                     /note="hypothetical protein; mutant has decreased Ty3
                     transposition; YLR125W is not an essential gene"
                     /codon_start=1
                     /product="hypothetical protein"
                     /protein_id="NP_013226.1"
                     /db_xref="GI:6323154"
                     /db_xref="SGD:S000004115"
                     /db_xref="GeneID:850816"
                     /translation="MGEILELTNKNFMSHLKKDITSQESLKSRIEDKNGDVASPKEDN
                     YPLLNETAAWPDGVITSEEGCSSSGEKENSGLCSEESSEEDPEEAEEESARAFGELVA
                     VLRDKDIPLNVLDEPQMKDWLEKYTGVYRSSWHG"
     gene            complement(<394765..>395520)
                     /locus_tag="YLR126C"
                     /db_xref="GeneID:850817"
     mRNA            complement(<394765..>395520)
                     /locus_tag="YLR126C"
                     /product="putative amidotransferase"
                     /transcript_id="NM_001182013.1"
                     /db_xref="GI:296146657"
                     /db_xref="GeneID:850817"
     CDS             complement(394765..395520)
                     /locus_tag="YLR126C"
                     /EC_number="2.4.2.-"
                     /note="Putative glutamine amidotransferase; has
                     Aft1p-binding motif in the promoter; may be involved in
                     copper and iron homeostasis; YLR126C is not an essential
                     protein; relocalizes from nucleus to cytoplasmic foci upon
                     DNA replication stress"
                     /codon_start=1
                     /product="putative amidotransferase"
                     /protein_id="NP_013227.1"
                     /db_xref="GI:6323155"
                     /db_xref="SGD:S000004116"
                     /db_xref="GeneID:850817"
                     /translation="MTVKKIAILYTDEDNEWSKPWGNFVDMAIKLLEQTRKLECIAED
                     VEYEVFHVQKNVFPQLSDLQKDEYLGIYITGSKYDSFDNEIEWIMKLRSFLNEMLTSK
                     TEYPPVAGICFGHQVIAAALGSSVGRNPKGFEGGVVSLKLNSVGQKLFGAQELNLSEV
                     HSDCVFDVPEGYQNWASSEKCQNQGFYRQNRVLTFQGHPEFNSDVAQKGLLKSQDKLT
                     LEEFNRYERQCQELDNNGIQAARNIWRLFLQKI"
     gene            complement(<395758..>398319)
                     /gene="APC2"
                     /locus_tag="YLR127C"
                     /gene_synonym="RSI1; TID2"
                     /db_xref="GeneID:850818"
     mRNA            complement(<395758..>398319)
                     /gene="APC2"
                     /locus_tag="YLR127C"
                     /gene_synonym="RSI1; TID2"
                     /product="anaphase promoting complex subunit 2"
                     /transcript_id="NM_001182014.1"
                     /db_xref="GI:296146658"
                     /db_xref="GeneID:850818"
     CDS             complement(395758..398319)
                     /gene="APC2"
                     /locus_tag="YLR127C"
                     /gene_synonym="RSI1; TID2"
                     /note="Subunit of the Anaphase-Promoting Complex/Cyclosome
                     (APC/C); which is a ubiquitin-protein ligase required for
                     degradation of anaphase inhibitors, including mitotic
                     cyclins, during the metaphase/anaphase transition;
                     component of the catalytic core of the APC/C; has
                     similarity to cullin Cdc53p"
                     /codon_start=1
                     /product="anaphase promoting complex subunit 2"
                     /protein_id="NP_013228.1"
                     /db_xref="GI:6323156"
                     /db_xref="SGD:S000004117"
                     /db_xref="GeneID:850818"
                     /translation="MSFQITPTRDLKVITDELQTLSSYIFHTNIVDDLNSLLTWMSPN
                     DAKSNHQLRPPSLRIKNIIKVLFPNNATTSPYSMINTSQANNSIVNEGNTNKELQLQL
                     FSTLKEFYIFQVRYHFFLHFNNINYLKDIQRWENYYEFPLRYVPIFDVNVNDWALELN
                     SLRHYLLNRNIKFKNNLRTRLDKLIMDDDFDLADNLIQWLKSANGSLSSTELIVNALY
                     SKINKFCEDNMSRVWNKRFMIMETFNKFINQYWSQFSKLVGCPEDDHELTTTVFNCFE
                     SNFLRIRTNEIFDICVLAYPDSKVTLLELRKIMKDFKDYTNIVTTFLSDFKKYILNPS
                     VTTVDALLRYVKTIKAFLVLDPTGRCLHSITTFVKPYFQERKHLVNVLLYAMLDLPEE
                     ELKEKINFNVDMKALLSLVDTLHDSDINQDTNITKRDKNKKSPFLWNLKVKGKRELNK
                     DLPIRHAMLYEHILNYYIAWVPEPNDMIPGNIKSSYIKTNLFEVLLDLFESREFFISE
                     FRNLLTDRLFTLKFYTLDEKWTRCLKLIREKIVKFTETSHSNYITNGILGLLETTAPA
                     ADADQSNLNSIDVMLWDIKCSEELCRKMHEVAGLDPIIFPKFISLLYWKYNCDTQGSN
                     DLAFHLPIDLERELQKYSDIYSQLKPGRKLQLCKDKGKVEIQLAFKDGRKLVLDVSLE
                     QCSVINQFDSPNDEPICLSLEQLSESLNIAPPRLTHLLDFWIQKGVLLKENGTYSVIE
                     HSEMDFDQAQKTAPMEIENSNYELHNDSEIERKYELTLQRSLPFIEGMLTNLGAMKLH
                     KIHSFLKITVPKDWGYNRITLQQLEGYLNTLADEGRLKYIANGSYEIVKNGHKNS"
     gene            <398530..>399433
                     /gene="DCN1"
                     /locus_tag="YLR128W"
                     /db_xref="GeneID:850819"
     mRNA            join(<398530..398532,398627..>399433)
                     /gene="DCN1"
                     /locus_tag="YLR128W"
                     /product="NEDD8 ligase DCN1"
                     /transcript_id="NM_001182015.1"
                     /db_xref="GI:296146659"
                     /db_xref="GeneID:850819"
     CDS             join(398530..398532,398627..399433)
                     /gene="DCN1"
                     /locus_tag="YLR128W"
                     /note="Scaffold-type E3 ligase; required for cullin
                     neddylation and ubiquitin ligase activation; contains a
                     ubiquitin-binding domain (UBA) for ubiquitin and Nedd8
                     (Rub1p) interaction and a PONY domain involved in cullin
                     binding and neddylation"
                     /codon_start=1
                     /product="NEDD8 ligase DCN1"
                     /protein_id="NP_013229.1"
                     /db_xref="GI:6323157"
                     /db_xref="SGD:S000004118"
                     /db_xref="GeneID:850819"
                     /translation="MSNNKIKRKDASPEQEAIESFTSLTKCDPKVSRKYLQRNHWNIN
                     YALNDYYDKEIGTFTDEVSTVAHPPVYPKELTQVFEHYINNNLFDIDSLVKFIEELGY
                     NLEDLATLCLAHLLGYKKLEEPLKREDFLSTWFMQGCSTISDMQECIKTLDVKLHEDL
                     QYFTQIYNYAFNLILDPNRKDIDTDEGIQYWKLFFQPEYPVRMEPDLLEAWFRFLRDE
                     GKTTISKDTWRMLLLFFKRYPTIQKIISDYDETAAWPFIIDEFYECLQDQQ"
     gene            <399657..>402488
                     /gene="DIP2"
                     /locus_tag="YLR129W"
                     /gene_synonym="UTP12"
                     /db_xref="GeneID:850820"
     mRNA            <399657..>402488
                     /gene="DIP2"
                     /locus_tag="YLR129W"
                     /gene_synonym="UTP12"
                     /product="Dip2p"
                     /transcript_id="NM_001182016.1"
                     /db_xref="GI:296146660"
                     /db_xref="GeneID:850820"
     CDS             399657..402488
                     /gene="DIP2"
                     /locus_tag="YLR129W"
                     /gene_synonym="UTP12"
                     /note="Nucleolar protein; specifically associated with the
                     U3 snoRNA, part of the large ribonucleoprotein complex
                     known as the small subunit (SSU) processome, required for
                     18S rRNA biogenesis, part of the active pre-rRNA
                     processing complex"
                     /codon_start=1
                     /product="Dip2p"
                     /protein_id="NP_013230.1"
                     /db_xref="GI:6323158"
                     /db_xref="SGD:S000004119"
                     /db_xref="GeneID:850820"
                     /translation="MVKSYQRFEQAAAFGVIASNANCVWIPASSGNSNGSGPGQLITS
                     ALEDVNIWDIKTGDLVSKLSDGLPPGASDARGAKPAECTYLEAHKDTDLLAVGYADGV
                     IKVWDLMSKTVLLNFNGHKAAITLLQFDGTGTRLISGSKDSNIIVWDLVGEVGLYKLR
                     SHKDSITGFWCQGEDWLISTSKDGMIKLWDLKTHQCIETHIAHTGECWGLAVKDDLLI
                     TTGTDSQVKIWKLDIENDKMGGKLTEMGIFEKQSKQRGLKIEFITNSSDKTSFFYIQN
                     ADKTIETFRIRKEEEIARGLKKREKRLKEKGLTEEEIAKSIKESYSSFILHPFQTIRS
                     LYKIKSASWTTVSSSKLELVLTTSSNTIEYYSIPYEKRDPTSPAPLKTHTIELQGQRT
                     DVRSIDISDDNKLLATASNGSLKIWNIKTHKCIRTFECGYALTCKFLPGGLLVILGTR
                     NGELQLFDLASSSLLDTIEDAHDAAIWSLDLTSDGKRLVTGSADKTVKFWDFKVENSL
                     VPGTKNKFLPVLKLHHDTTLELTDDILCVRVSPDDRYLAISLLDNTVKVFFLDSMKFY
                     LSLYGHKLPVLSIDISFDSKMIITSSADKNIKIWGLDFGDCHKSLFAHQDSIMNVKFL
                     PQSHNFFSCSKDAVVKYWDGEKFECIQKLYAHQSEVWALAVATDGGFVVSSSHDHSIR
                     IWEETEDQVFLEEEKEKELEEQYEDTLLTSLEEGNGDDAFKADASGEGVEDEASGVHK
                     QTLESLKAGERLMEALDLGIAEIEGLEAYNRDMKLWQRKKLGEAPIKPQGNAVLIAVN
                     KTPEQYIMDTLLRIRMSQLEDALMVMPFSYVLKFLKFIDTVMQNKTLLHSHLPLICKN
                     LFFIIKFNHKELVSQKNEELKLQINRVKTELRSALKSTEDDLGFNVQGLKFVKQQWNL
                     RHNYEFVDEYDQQEKESNSARKRVFGTVI"
     gene            complement(<402794..>404062)
                     /gene="ZRT2"
                     /locus_tag="YLR130C"
                     /db_xref="GeneID:850821"
     mRNA            complement(<402794..>404062)
                     /gene="ZRT2"
                     /locus_tag="YLR130C"
                     /product="low-affinity Zn(2+) transporter ZRT2"
                     /transcript_id="NM_001182017.1"
                     /db_xref="GI:296146661"
                     /db_xref="GeneID:850821"
     CDS             complement(402794..404062)
                     /gene="ZRT2"
                     /locus_tag="YLR130C"
                     /note="Low-affinity zinc transporter of the plasma
                     membrane; transcription is induced under low-zinc
                     conditions by the Zap1p transcription factor"
                     /codon_start=1
                     /product="low-affinity Zn(2+) transporter ZRT2"
                     /protein_id="NP_013231.1"
                     /db_xref="GI:6323159"
                     /db_xref="SGD:S000004120"
                     /db_xref="GeneID:850821"
                     /translation="MVDLIARDDSVDTCQASNGYNGHAGLRILAVFIILISSGLGVYF
                     PILSSRYSFIRLPNWCFFIAKFFGSGVIVATAFVHLLQPAAEALGDECLGGTFAEYPW
                     AFGICLMSLFLLFFTEIITHYFVAKTLGHDHGDHGEVTSIDVDAPSSGFVIRNMDSDP
                     VSFNNEAAYSIHNDKTPYTTRNEEIVATPIKEKEPGSNVTNYDLEPGKTESLANELVP
                     TSSHATNLASVPGKDHYSHENDHQDVSQLATRIEEEDKEQYLNQILAVFILEFGIIFH
                     SVFVGLSLSVAGEEFETLFIVLTFHQMFEGLGLGTRVAETNWPESKKYMPWLMGLAFT
                     LTSPIAVAVGIGVRHSWIPGSRRALIANGVFDSISSGILIYTGLVELMAHEFLYSNQF
                     KGPDGLKKMLSAYLIMCCGAALMALLGKWA"
     gene            complement(<404510..>406822)
                     /gene="ACE2"
                     /locus_tag="YLR131C"
                     /db_xref="GeneID:850822"
     mRNA            complement(<404510..>406822)
                     /gene="ACE2"
                     /locus_tag="YLR131C"
                     /product="Ace2p"
                     /transcript_id="NM_001182018.1"
                     /db_xref="GI:296146662"
                     /db_xref="GeneID:850822"
     CDS             complement(404510..406822)
                     /gene="ACE2"
                     /locus_tag="YLR131C"
                     /note="Transcription factor required for septum
                     destruction after cytokinesis; phosphorylation by Cbk1p
                     blocks nuclear exit during M/G1 transition, causing
                     localization to daughter cell nuclei, and also increases
                     Ace2p activity; phosphorylation by Cdc28p and Pho85p
                     prevents nuclear import during cell cycle phases other
                     than cytokinesis; part of RAM network that regulates
                     cellular polarity and morphogenesis; ACE2 has a paralog,
                     SWI5, that arose from the whole genome duplication"
                     /codon_start=1
                     /product="Ace2p"
                     /protein_id="NP_013232.1"
                     /db_xref="GI:6323160"
                     /db_xref="SGD:S000004121"
                     /db_xref="GeneID:850822"
                     /translation="MDNVVDPWYINPSGFAKDTQDEEYVQHHDNVNPTIPPPDNYILN
                     NENDDGLDNLLGMDYYNIDDLLTQELRDLDIPLVPSPKTGDGSSDKKNIDRTWNLGDE
                     NNKVSHYSKKSMSSHKRGLSGTAIFGFLGHNKTLSISSLQQSILNMSKDPQPMELINE
                     LGNHNTVKNNNDDFDHIRENDGENSYLSQVLLKQQEELRIALEKQKEVNEKLEKQLRD
                     NQIQQEKLRKVLEEQEEVAQKLVSGATNSNSKPGSPVILKTPAMQNGRMKDNAIIVTT
                     NSANGGYQFPPPTLISPRMSNTSINGSPSRKYHRQRYPNKSPESNGLNLFSSNSGYLR
                     DSELLSFSPQNYNLNLDGLTYNDHNNTSDKNNNDKKNSTGDNIFRLFEKTSPGGLSIS
                     PRINGNSLRSPFLVGTDKSRDDRYAAGTFTPRTQLSPIHKKRESVVSTVSTISQLQDD
                     TEPIHMRNTQNPTLRNANALASSSVLPPIPGSSNNTPIKNSLPQKHVFQHTPVKAPPK
                     NGSNLAPLLNAPDLTDHQLEIKTPIRNNSHCEVESYPQVPPVTHDIHKSPTLHSTSPL
                     PDEIIPRTTPMKITKKPTTLPPGTIDQYVKELPDKLFECLYPNCNKVFKRRYNIRSHI
                     QTHLQDRPYSCDFPGCTKAFVRNHDLIRHKISHNAKKYICPCGKRFNREDALMVHRSR
                     MICTGGKKLEHSINKKLTSPKKSLLDSPHDTSPVKETIARDKDGSVLMKMEEQLRDDM
                     RKHGLLDPPPSTAAHEQNSNRTLSNETDAL"
     gene            complement(<407283..>408155)
                     /gene="USB1"
                     /locus_tag="YLR132C"
                     /db_xref="GeneID:850823"
     mRNA            complement(<407283..>408155)
                     /gene="USB1"
                     /locus_tag="YLR132C"
                     /product="Usb1p"
                     /transcript_id="NM_001182019.1"
                     /db_xref="GI:296146663"
                     /db_xref="GeneID:850823"
     CDS             complement(407283..408155)
                     /gene="USB1"
                     /locus_tag="YLR132C"
                     /EC_number="3.1.4.-"
                     /note="Putative phosphodiesterase specific for U6 snRNA 3'
                     end modification; trims the 3' poly(u) tract to leave a
                     terminal 3' phosphate; human homolog, hUSB1 (aka C16orf57)
                     produces a 2',3' cyclic phosphate; mutations in hUSB1 are
                     associated with a rare skin condition (OMIM 604173);
                     essential protein that localizes to the nucleus and
                     mitochondria; overexpression suppresses the respiratory
                     defects of oxa1 and mtf2 mutants"
                     /codon_start=1
                     /product="Usb1p"
                     /protein_id="NP_013233.1"
                     /db_xref="GI:6323161"
                     /db_xref="SGD:S000004122"
                     /db_xref="GeneID:850823"
                     /translation="MEFISADYSSSDGSDTESESSNKSEVQIEYTEKTCIQKADSTDL
                     PAIPDSIILKYHIPPNLQKYEHQDMNMSRFWRSFTYFEWRPTPAIHRQLQKIICKYKE
                     TFMKQEYTNPYQLVDFDPLFISHLGAPKPLHVSLTRSLLFETEEQRHVFIQEMRNGLR
                     NNEITPFKLQICSYPKLYISERANTLYLGLPVSECPNKAQISPFKTIIAEALQKSGIS
                     NYQDLIVSRQNLHVSIAIASNPSKATLKRYQQLNETMGALLLLNNDFAYKLEFLVNSI
                     YCDENRHSIRIPFN"
     gene            <408445..>410193
                     /gene="CKI1"
                     /locus_tag="YLR133W"
                     /db_xref="GeneID:850824"
     mRNA            <408445..>410193
                     /gene="CKI1"
                     /locus_tag="YLR133W"
                     /product="bifunctional choline kinase/ethanolamine kinase
                     CKI1"
                     /transcript_id="NM_001182020.1"
                     /db_xref="GI:296146664"
                     /db_xref="GeneID:850824"
     CDS             408445..410193
                     /gene="CKI1"
                     /locus_tag="YLR133W"
                     /EC_number="2.7.1.32"
                     /note="Choline kinase; catalyzes the first step in
                     phosphatidylcholine synthesis via the CDP-choline (Kennedy
                     pathway); exhibits some ethanolamine kinase activity
                     contributing to phosphatidylethanolamine synthesis via the
                     CDP-ethanolamine pathway; CKI1 has a paralog, EKI1, that
                     arose from the whole genome duplication"
                     /codon_start=1
                     /product="bifunctional choline kinase/ethanolamine kinase
                     CKI1"
                     /protein_id="NP_013234.1"
                     /db_xref="GI:6323162"
                     /db_xref="SGD:S000004123"
                     /db_xref="GeneID:850824"
                     /translation="MVQESRPGSVRSYSVGYQARSRSSSQRRHSLTRQRSSQRLIRTI
                     SIESDVSNITDDDDLRAVNEGVAGVQLDVSETANKGPRRASATDVTDSLGSTSSEYIE
                     IPFVKETLDASLPSDYLKQDILNLIQSLKISKWYNNKKIQPVAQDMNLVKISGAMTNA
                     IFKVEYPKLPSLLLRIYGPNIDNIIDREYELQILARLSLKNIGPSLYGCFVNGRFEQF
                     LENSKTLTKDDIRNWKNSQRIARRMKELHVGVPLLSSERKNGSACWQKINQWLRTIEK
                     VDQWVGDPKNIENSLLCENWSKFMDIVDRYHKWLISQEQGIEQVNKNLIFCHNDAQYG
                     NLLFTAPVMNTPSLYTAPSSTSLTSQSSSLFPSSSNVIVDDIINPPKQEQSQDSKLVV
                     IDFEYAGANPAAYDLANHLSEWMYDYNNAKAPHQCHADRYPDKEQVLNFLYSYVSHLR
                     GGAKEPIDEEVQRLYKSIIQWRPTVQLFWSLWAILQSGKLEKKEASTAITREEIGPNG
                     KKYIIKTEPESPEEDFVENDDEPEAGVSIDTFDYMAYGRDKIAVFWGDLIGLGIITEE
                     ECKNFSSFKFLDTSYL"
     gene            <410723..>412414
                     /gene="PDC5"
                     /locus_tag="YLR134W"
                     /db_xref="GeneID:850825"
     mRNA            <410723..>412414
                     /gene="PDC5"
                     /locus_tag="YLR134W"
                     /product="indolepyruvate decarboxylase 5"
                     /transcript_id="NM_001182021.1"
                     /db_xref="GI:296146665"
                     /db_xref="GeneID:850825"
     CDS             410723..412414
                     /gene="PDC5"
                     /locus_tag="YLR134W"
                     /EC_number="4.1.1.74"
                     /EC_number="4.1.1.72"
                     /EC_number="4.1.1.1"
                     /EC_number="4.1.1.-"
                     /note="Minor isoform of pyruvate decarboxylase; key enzyme
                     in alcoholic fermentation, decarboxylates pyruvate to
                     acetaldehyde, regulation is glucose- and
                     ethanol-dependent, repressed by thiamine, involved in
                     amino acid catabolism"
                     /codon_start=1
                     /product="indolepyruvate decarboxylase 5"
                     /protein_id="NP_013235.1"
                     /db_xref="GI:6323163"
                     /db_xref="SGD:S000004124"
                     /db_xref="GeneID:850825"
                     /translation="MSEITLGKYLFERLSQVNCNTVFGLPGDFNLSLLDKLYEVKGMR
                     WAGNANELNAAYAADGYARIKGMSCIITTFGVGELSALNGIAGSYAEHVGVLHVVGVP
                     SISSQAKQLLLHHTLGNGDFTVFHRMSANISETTAMITDIANAPAEIDRCIRTTYTTQ
                     RPVYLGLPANLVDLNVPAKLLETPIDLSLKPNDAEAEAEVVRTVVELIKDAKNPVILA
                     DACASRHDVKAETKKLMDLTQFPVYVTPMGKGAIDEQHPRYGGVYVGTLSRPEVKKAV
                     ESADLILSIGALLSDFNTGSFSYSYKTKNIVEFHSDHIKIRNATFPGVQMKFALQKLL
                     DAIPEVVKDYKPVAVPARVPITKSTPANTPMKQEWMWNHLGNFLREGDIVIAETGTSA
                     FGINQTTFPTDVYAIVQVLWGSIGFTVGALLGATMAAEELDPKKRVILFIGDGSLQLT
                     VQEISTMIRWGLKPYIFVLNNNGYTIEKLIHGPHAEYNEIQGWDHLALLPTFGARNYE
                     THRVATTGEWEKLTQDKDFQDNSKIRMIEVMLPVFDAPQNLVKQAQLTAATNAKQ"
     rep_origin      412668..412896
                     /note="ARS1215;
                     Autonomously Replicating Sequence"
                     /db_xref="SGD:S000118474"
     gene            <413281..>415527
                     /gene="SLX4"
                     /locus_tag="YLR135W"
                     /db_xref="GeneID:850826"
     mRNA            <413281..>415527
                     /gene="SLX4"
                     /locus_tag="YLR135W"
                     /product="Slx4p"
                     /transcript_id="NM_001182022.1"
                     /db_xref="GI:296146666"
                     /db_xref="GeneID:850826"
     CDS             413281..415527
                     /gene="SLX4"
                     /locus_tag="YLR135W"
                     /note="Endonuclease involved in processing DNA; acts
                     during recombination and repair; promotes template
                     switching during break-induced replication (BIR), causing
                     non-reciprocal translocations (NRTs); cleaves branched
                     structures in a complex with Slx1p; involved interstrand
                     cross-link repair and in Rad1p/Rad10p-dependent removal of
                     3'-nonhomologous tails during DSBR via single-strand
                     annealing; relative distribution to nuclear foci increases
                     upon DNA replication stress"
                     /codon_start=1
                     /product="Slx4p"
                     /protein_id="NP_013236.1"
                     /db_xref="GI:6323164"
                     /db_xref="SGD:S000004125"
                     /db_xref="GeneID:850826"
                     /translation="MELQRAQRNLKFLQNEDYVNVTDQTNLNGESQNAYSLGMETQVP
                     EMQFSLSSDDDSIGTQVKSVTAQKSPMTQETTKNDTERNKDVDKSCNPVSTSHPDLGG
                     SNIEENIFINTQIQSRLDDAEEETNLKLKLEKFKYSFKSSNADDTHSNANVTAKRRPA
                     IRKANSKLKTKPKTKRDPKIIKNITDFNINNYERSRTASLLKQLSGKHKKVLDIIKTQ
                     NEGNSDKPPRARNNKGEKATFDTYSEQEWKDIMKLLLQKFPQSEETDLNEVQKFLYGS
                     EKSSNSLDNQESSQQRLWTASQLPPELPDEAIQPEQEERIRDTQSAVNFLSLSQVMDD
                     KSEIMKDEESIIISRGDSTSSQEYGNGLEPQQPVGNVVGEDIELAVGTRINAFSLTDY
                     KACKPMSVEVSRRCENSTDNDYDNISIVSDTTDETSTLFPLDQYRYVFIENDERPPLA
                     TDTIGSTQFFTPNTSPLDGIIDLTQESFKAVRSLISPLKVENNKTGVTSQASNQVQVP
                     ATRTPTIIPQKNLTTTLKTEEEKNNIGSSIRVKLLQESVVKLNPKLVKHNFYRVEAND
                     SEEEETEFDDQFCIADIQLVDSSKISTKDSTQNPTTSNDIIDTSAASSIASPEKFCEI
                     MMSQSMKELRQSLKTVGLKPMRTKVEIIQSLQTASQILSTANPDNKGEHGGVANFSKI
                     EIFDHLTELIEAFPDFLERIYTFEPIPLNELIEKLFSAEPFVSQIDEMTIREWADVQG
                     ICLRNDKK"
     gene            complement(<415801..>416658)
                     /gene="TIS11"
                     /locus_tag="YLR136C"
                     /gene_synonym="CTH2"
                     /db_xref="GeneID:850827"
     mRNA            complement(<415801..>416658)
                     /gene="TIS11"
                     /locus_tag="YLR136C"
                     /gene_synonym="CTH2"
                     /product="Tis11p"
                     /transcript_id="NM_001182023.1"
                     /db_xref="GI:296146667"
                     /db_xref="GeneID:850827"
     CDS             complement(415801..416658)
                     /gene="TIS11"
                     /locus_tag="YLR136C"
                     /gene_synonym="CTH2"
                     /note="mRNA-binding protein expressed during iron
                     starvation; binds to a sequence element in the
                     3'-untranslated regions of specific mRNAs to mediate their
                     degradation; involved in iron homeostasis; protein
                     increases in abundance and relative distribution to the
                     nucleus increases upon DNA replication stress; TIS11 has a
                     paralog, CTH1, that arose from the whole genome
                     duplication"
                     /codon_start=1
                     /product="Tis11p"
                     /protein_id="NP_013237.1"
                     /db_xref="GI:6323165"
                     /db_xref="SGD:S000004126"
                     /db_xref="GeneID:850827"
                     /translation="MWAQLSYTRPESQKTDLTSLFSTDQEQNPLNDYQYQINIRELEE
                     YYNKTILNEDNIQETSSEISSAVSFSPPKNTNAIQPGLLYDPQLMNPFLPSAHLNSTA
                     PTTFKKKLEVQINPDYVPKSSQLPLTSQNLQQLSQQKPKNDASFSSEKESSAQPKVKS
                     QVQETPKQLYKTELCESFTLKGSCPYGSKCQFAHGLGELKVKKSCKNFRTKPCVNWEK
                     LGYCPYGRRCCFKHGDDNDIAVYVKAGTYCNVSSTSKQSDEKRSNGRGSAKKKNLNVK
                     VKALQRMTW"
     gene            <417006..>418109
                     /gene="RKM5"
                     /locus_tag="YLR137W"
                     /db_xref="GeneID:850828"
     mRNA            <417006..>418109
                     /gene="RKM5"
                     /locus_tag="YLR137W"
                     /product="Rkm5p"
                     /transcript_id="NM_001182024.1"
                     /db_xref="GI:296146668"
                     /db_xref="GeneID:850828"
     CDS             417006..418109
                     /gene="RKM5"
                     /locus_tag="YLR137W"
                     /EC_number="2.1.1.-"
                     /note="Protein lysine methyltransferase; monomethylates
                     Lys-46 of the ribosomal large subunit Rpl1a/Rpl1b; member
                     of the seven beta-strand methyltransferase superfamily;
                     orthologs only found among fungal species"
                     /codon_start=1
                     /product="Rkm5p"
                     /protein_id="NP_013238.1"
                     /db_xref="GI:6323166"
                     /db_xref="SGD:S000004127"
                     /db_xref="GeneID:850828"
                     /translation="MAFKLWLLDEETIYEHVFERYTQLEGQSGKLAQDLGIQDRRGGV
                     LEITFEPSGLEGGRKKKRVRRRNKASSVEEDQNVAVDSYHVSVGQSISSLRSSRDNGN
                     STTGYVLWSTTPFFINWLLYSTSAAPFRLGSQVEVTCGSSCEGHKLELPRLVDLTGAD
                     RGKRGILELGAGISGILPVILGNFVDTYVSTDQKGILNKLKDNIMENLSQLTRKRCIS
                     RSLRLELPTVEPVGDADITAASLPSKSTLHLEVAALDWEKINLQDKKTHSLHPELSLI
                     GETCSSVYVIAMDVIYNEYLIDPFLKTLKQLKHWLQTTYNLQFHVLVGIHLRSQEVTT
                     LFLEKAIIEYDFTVYDIVDQVIQESRFNFYLIT"
     gene            <418437..>421394
                     /gene="NHA1"
                     /locus_tag="YLR138W"
                     /db_xref="GeneID:850829"
     mRNA            <418437..>421394
                     /gene="NHA1"
                     /locus_tag="YLR138W"
                     /product="Nha1p"
                     /transcript_id="NM_001182025.1"
                     /db_xref="GI:296146669"
                     /db_xref="GeneID:850829"
     CDS             418437..421394
                     /gene="NHA1"
                     /locus_tag="YLR138W"
                     /note="Na+/H+ antiporter; involved in sodium and potassium
                     efflux through the plasma membrane; required for alkali
                     cation tolerance at acidic pH"
                     /codon_start=1
                     /product="Nha1p"
                     /protein_id="NP_013239.1"
                     /db_xref="GI:6323167"
                     /db_xref="SGD:S000004128"
                     /db_xref="GeneID:850829"
                     /translation="MAIWEQLEVSKAHVAYACVGVFSSIFSLVSLYVKEKLYIGESTV
                     AGIFGLIVGPVCLNWFNPLKWGNSDSITLEITRIVLCLQIFAVAVELPRKYMLKHWVS
                     VTMLLLPVMTAGWLIIGLFVWILIPGLNFSASLLISACITATDPILAQSVVSGKFAQR
                     VPGHLRNLLSAESGCNDGMAFPFLFLSMNLILHPGNGREIVKDWICVTILYECLFGCL
                     LGCFIGYVGRITIRFAEKKNIIDRESFLAFYVVLAFMCAGFGSILGVDDLLVSFAAGA
                     TFAWDGWFSQKTQESNVSTVIDLLLNYAYFIYFGAIIPWSQFNNGEIGTNVWRLIILS
                     IVVIFLRRIPAVMILRPLIPDIKSWREALFVGHFGPIGVGAIFAAILARGELESTFSD
                     EPTPLNVVPSKEESKHWQLIACIWPITCFFIVTSIIVHGSSVAIITLGRHLNTITLTK
                     TFTTHTTNGDNGKSSWMQRLPSLDKAGRSFSLHRMDTQMTLSGDEGEAEEGGGRKGLA
                     GGEDEEGLNNDQIGSVATSGIPARPAGGMPRRRKLSRKEKRLNRRQKLRNKGREIFSS
                     RSKNEMYDDDELNDLGRERLQKEKEARAATFALSTAVNTQRNEEIGMGGDEEEDEYTP
                     EKEYSDNYNNTPSFESSERSSSLRGRTYVPRNRYDGEETESEIESEDEMENESERSMA
                     SSEERRIRKMKEEEMKPGTAYLDGNRMIIENKQGEILNQVDIEDRNEARDDEVSVDST
                     AHSSLTTTMTNLSSSSGGRLKRILTPTSLGKIHSLVDKGKDKNKNSKYHAFKIDNLLI
                     IENEDGDVIKRYKINPHKSDDDKSKNRPRNDSVVSRALTAVGLKSKANSGVPPPVDEE
                     KAIEGPSRKGPGMLKKRTLTPAPPRGVQDSLDLEDEPSSEEDLGDSYNMDDSEDYDDN
                     AYESETEFERQRRLNALGEMTAPADQDDEELPPLPVEAQTGNDGPGTAEGKKKQKSAA
                     VKSALSKTLGLNK"
     gene            complement(<421542..>423473)
                     /gene="SLS1"
                     /locus_tag="YLR139C"
                     /db_xref="GeneID:850830"
     mRNA            complement(<421542..>423473)
                     /gene="SLS1"
                     /locus_tag="YLR139C"
                     /product="Sls1p"
                     /transcript_id="NM_001182026.1"
                     /db_xref="GI:296146670"
                     /db_xref="GeneID:850830"
     CDS             complement(421542..423473)
                     /gene="SLS1"
                     /locus_tag="YLR139C"
                     /note="Mitochondrial membrane protein; coordinates
                     expression of mitochondrially-encoded genes; may
                     facilitate delivery of mRNA to membrane-bound translation
                     machinery"
                     /codon_start=1
                     /product="Sls1p"
                     /protein_id="NP_013240.1"
                     /db_xref="GI:6323168"
                     /db_xref="SGD:S000004129"
                     /db_xref="GeneID:850830"
                     /translation="MWKFNKKLARLTYRLYSSSGPSSPLHGKKKLPQNLKFVVLNPTQ
                     SGLVKNDQKQPRHRPSKKRSHKETGDNNLDFGSKLLVFEKQNSLDSALNSIRLKKPTS
                     ASLPSLEYNALLQSLTSSYNRYQLREFISTHQPDSSSHLTHWKKSKLSQYIIEKIWNC
                     QPISTPTTPTGIKSTSLTFQFDSPREIFLLLITQNGKILTNFNKLGLTFIISIQDNEL
                     TVKGSPSLLKYAEISLNKIWSNITHENVRMYSLMPSKDVINLIQKETHTFFEYLPDLQ
                     MYKISALSTKKISMAKVFLLNAVASNPNTTQHHHTIASPALKTELYPFNNTLENLDWL
                     NKSQDWARLQSVVPKNCTDLMTPTENATPELTDAQVSQFESSLSKNIPSLSPSDSISQ
                     SLSITLGHSLQSASFSSIFQPLIHKSFISKLLNLPMYKESSSSAVPVPVPLDQHLITN
                     AHQSFIQLNFTPVPPTSGSSSSPFLQIWFEIDEFDNIVTTSMRPLLKLQENSVILRTP
                     QCQTDYKITSDYIQDLLPDFDQTNPDAWLSEQKGLQEFLLKSHWKLNKYQNLMKKINI
                     SLPDNLIQQYQLTDVLTHRVLNLRFPTNTAQDDKYIIQYSDISRGFLNNGSYRQLDFI
                     NVNPSETSLKTFINDVLSF"
     gene            <423683..>424774
                     /gene="RRN5"
                     /locus_tag="YLR141W"
                     /db_xref="GeneID:850832"
     mRNA            <423683..>424774
                     /gene="RRN5"
                     /locus_tag="YLR141W"
                     /product="Rrn5p"
                     /transcript_id="NM_001182028.1"
                     /db_xref="GI:296146671"
                     /db_xref="GeneID:850832"
     CDS             423683..424774
                     /gene="RRN5"
                     /locus_tag="YLR141W"
                     /note="Protein involved in transcription of rDNA by RNA
                     polymerase I; transcription factor, member of UAF
                     (upstream activation factor) family along with Rrn9p and
                     Rrn10p"
                     /codon_start=1
                     /product="Rrn5p"
                     /protein_id="NP_013242.1"
                     /db_xref="GI:6323170"
                     /db_xref="SGD:S000004131"
                     /db_xref="GeneID:850832"
                     /translation="MEHQQLRKYVELYNKEVEEFYNGAASGRPAEFHPSKVHVKSIHE
                     KAGTANAGVEISSVGVDWDSEEKNTFFWCLSRYSIHRVDEWRSLLPRKSAMEILGYYR
                     LLRRASASARSRKAGDDGAPIAYEMSAEWVALETKLSETVMAITEGAAEVADEEGHCE
                     GLIDYESWKRRWVAIYSHSRIAEIRPLPRHALPLSRSATQTLERCVSRYTRTLLWCTA
                     LAGMASRSVSARAAESRGHKSLPTVVTRRQVERALCTEARSRDLHVLPRRIVLTLRKW
                     ELDYPREGKLFRTKEMAHLFLQSQLSRRDAPPVHQDENQENQENQENQEQDNTASEGE
                     SEAERDEIDEADLFRSALHENQLLKWLSK"
     gene            <425186..>426616
                     /gene="PUT1"
                     /locus_tag="YLR142W"
                     /db_xref="GeneID:850833"
     mRNA            <425186..>426616
                     /gene="PUT1"
                     /locus_tag="YLR142W"
                     /product="proline dehydrogenase"
                     /transcript_id="NM_001182029.1"
                     /db_xref="GI:296146672"
                     /db_xref="GeneID:850833"
     CDS             425186..426616
                     /gene="PUT1"
                     /locus_tag="YLR142W"
                     /EC_number="1.5.5.2"
                     /note="Proline oxidase; nuclear-encoded mitochondrial
                     protein involved in utilization of proline as sole
                     nitrogen source; PUT1 transcription is induced by Put3p in
                     the presence of proline and the absence of a preferred
                     nitrogen source"
                     /codon_start=1
                     /product="proline dehydrogenase"
                     /protein_id="NP_013243.1"
                     /db_xref="GI:6323171"
                     /db_xref="SGD:S000004132"
                     /db_xref="GeneID:850833"
                     /translation="MIASKSSLLVTKSRIPSLCFPLIKRSYVSKTPTHSNTAANLMVE
                     TPAANANGNSVMAPPNSINFLQTLPKKELFQLGFIGIATLNSFFLNTIIKLFPYIPIP
                     VIKFFVSSLYCGGENFKEVIECGKRLQKRGISNMMLSLTIENSEGTKSLSSTPVDQIV
                     KETISSVHNILLPNIIGQLESKPINDIAPGYIALKPSALVDNPHEVLYNFSNPAYKAQ
                     RDQLIENCSKITKEIFELNQSLLKKYPERKAPFMVSTIDAEKYDLQENGVYELQRILF
                     QKFNPTSSKLISCVGTWQLYLRDSGDHILHELKLAQENGYKLGLKLVRGAYIHSEKNR
                     NQIIFGDKTGTDENYDRIITQVVNDLIINGEDSYFGHLVVASHNYQSQMLVTNLLKST
                     QDNSYAKSNIVLGQLLGMADNVTYDLITNHGAKNIIKYVPWGPPLETKDYLLRRLQEN
                     GDAVRSDNGWPLIKAIAKSIPKRVGL"
     gene            427132..427203
                     /locus_tag="tD(GUC)L1"
                     /db_xref="GeneID:850834"
     tRNA            427132..427203
                     /locus_tag="tD(GUC)L1"
                     /product="tRNA-Asp"
                     /note="Aspartate tRNA (tRNA-Asp), predicted by tRNAscan-SE
                     analysis"
                     /db_xref="SGD:S000006541"
                     /db_xref="GeneID:850834"
     gene            <427329..>429386
                     /gene="DPH6"
                     /locus_tag="YLR143W"
                     /db_xref="GeneID:850835"
     mRNA            <427329..>429386
                     /gene="DPH6"
                     /locus_tag="YLR143W"
                     /product="Dph6p"
                     /transcript_id="NM_001182030.1"
                     /db_xref="GI:296146673"
                     /db_xref="GeneID:850835"
     CDS             427329..429386
                     /gene="DPH6"
                     /locus_tag="YLR143W"
                     /EC_number="6.3.1.14"
                     /note="Diphthamide synthetase; catalyzes the last
                     amidation step of diphthamide biosynthesis using ammonium
                     and ATP; evolutionarily conserved in eukaryotes; dph6
                     mutants exhibit diphthine accumulation and resistance to
                     sordarin, which is indicative of defects in diphthamide
                     formation on EF2; green fluorescent protein (GFP)-tagged
                     protein localizes to the cytoplasm; DPH6/YLR143W is not an
                     essential gene"
                     /codon_start=1
                     /product="Dph6p"
                     /protein_id="NP_013244.1"
                     /db_xref="GI:6323172"
                     /db_xref="SGD:S000004133"
                     /db_xref="GeneID:850835"
                     /translation="MKFIALISGGKDSFYNIFHCLKNNHELIALGNIYPKESEEQELD
                     SFMFQTVGHDLIDYYSKCIGVPLFRRSILRNTSNNVELNYTATQDDEIEELFELLRTV
                     KDKIPDLEAVSVGAILSSYQRTRVENVCSRLGLVVLSYLWQRDQAELMGEMCLMSKDV
                     NNVENDTNSGNKFDARIIKVAAIGLNEKHLGMSLPMMQPVLQKLNQLYQVHICGEGGE
                     FETMVLDAPFFQHGYLELIDIVKCSDGEVHNARLKVKFQPRNLSKSFLLNQLDQLPVP
                     SIFGNNWQDLTQNLPKQQAKTGEQRFENHMSNALPQTTINKTNDKLYISNLQSRKSET
                     VEKQSEDIFTELADILHSNQIPRNHILSASLLIRDMSNFGKINKIYNEFLDLSKYGPL
                     PPSRACVGSKCLPEDCHVQLSVVVDVKNTGKEKINKNKGGLHVQGRSYWAPCNIGPYS
                     QSTWLNDDANQVSFISGQIGLVPQSMEILGTPLTDQIVLALQHFDTLCETIGAQEKLL
                     MTCYISDESVLDSVIKTWAFYCSNMNHRSDLWMDKSDDVEKCLVLVKISELPRGAVAE
                     FGGVTCKRLIVDDNDSDKKEREENDDVSTVFQKLNLNIEGFHNTTVSAFGYNRNFITG
                     FVDSREELELILEKTPKSAQITLYYNPKEIITFHHHIGYYPVEKLFDYRGKEHRFGLH
                     IRS"
     gene            complement(<429677..>432016)
                     /gene="ACF2"
                     /locus_tag="YLR144C"
                     /gene_synonym="ENG2; PCA1"
                     /db_xref="GeneID:850836"
     mRNA            complement(<429677..>432016)
                     /gene="ACF2"
                     /locus_tag="YLR144C"
                     /gene_synonym="ENG2; PCA1"
                     /product="Acf2p"
                     /transcript_id="NM_001182031.1"
                     /db_xref="GI:296146674"
                     /db_xref="GeneID:850836"
     CDS             complement(429677..432016)
                     /gene="ACF2"
                     /locus_tag="YLR144C"
                     /gene_synonym="ENG2; PCA1"
                     /EC_number="3.2.1.6"
                     /note="Intracellular beta-1,3-endoglucanase; expression is
                     induced during sporulation; may have a role in cortical
                     actin cytoskeleton assembly; protein abundance increases
                     in response to DNA replication stress"
                     /codon_start=1
                     /product="Acf2p"
                     /protein_id="NP_013245.1"
                     /db_xref="GI:6323173"
                     /db_xref="SGD:S000004134"
                     /db_xref="GeneID:850836"
                     /translation="MCYSRQAIPPPVPNRPGGTTNRGPPPLPPRANVQPPVCSSENSS
                     KPRENRVAGESLRTPSSSNPLADSQVNSDNIFQSPVLSNLKAPPSVFNKVQHPVPKPN
                     IDDQSVDPLETNKFYTNMLLDDNTQPIWTHPYSIWFSRDPELFGLAANHTLASQRVFD
                     TTTNPPRFYFNPTNIKSFVFKAREFVSSNDIKLEFRDMKHMSMCLLMSLSSSQFIEFP
                     LVQGMGFVTAIYHDLGFELRSAVGFRSLERISVNERYGKYNIQLENNRNWILYLTSPD
                     YSFPQDFQISLLDSNTIISSHKINGLICQLSADSVPSIDMAAGCYPVYCDLSGQTVDE
                     HFTNYRFNYTVAGYSQSGTTLMYALPHHKAAFTPEMQEREIASSLDSTVKGLMTGYLT
                     NSFDMQVQVPQELGFEPVALSLNKKADYSQEKLSKIREAAVQEVQLSDPQQESNIDSM
                     YFSGKILAKYAWILYVTHYILHDENLTKELLSKLTIAMERFISNQQVLPLNYDVSWKG
                     IISSGSSSQDFGNSYYNDHHFHYSYHVITAAIISLVDSDLSGVTNNSWLENNRDWVEC
                     LIRDYSGVDNDDPYFPQFRSFDWFNGHSWAKGLFPSGDGKDEESTSEDVNSCYAIKLW
                     GLVTGNSKLTDIANLQLGIMRNVFQSYFLYESNNTVQPKEFIGNKVSGILFENKIDHA
                     TYFGMEPQYIHMIHAIPITSASSWVRTPNFVKEEWEEKMQPIIDQVNDGWKGIIMLNM
                     ALLDPKFSYDFFSQPDFNRNFLDNGQSLTWSLAYSGAFS"
     gene            <432168..>432773
                     /gene="RMP1"
                     /locus_tag="YLR145W"
                     /db_xref="GeneID:850837"
     mRNA            <432168..>432773
                     /gene="RMP1"
                     /locus_tag="YLR145W"
                     /product="Rmp1p"
                     /transcript_id="NM_001182032.1"
                     /db_xref="GI:296146675"
                     /db_xref="GeneID:850837"
     CDS             432168..432773
                     /gene="RMP1"
                     /locus_tag="YLR145W"
                     /note="Subunit of RNase MRP; RNase MRP processes pre-rRNA
                     and has a role in cell cycle-regulated degradation of
                     daughter cell-specific mRNAs; unlike most subunits, not
                     shared between RNase MRP and nuclear RNase P"
                     /codon_start=1
                     /product="Rmp1p"
                     /protein_id="NP_013246.1"
                     /db_xref="GI:6323174"
                     /db_xref="SGD:S000004135"
                     /db_xref="GeneID:850837"
                     /translation="MDEMDNVIRSLEQEYRLILLLNHRNKNQHRAASWYGSFNEMKRN
                     CGQIITLFSSRRLQAKRLKDVEWVKLHRLLQRALFRQLKRWYWQFNGVIALGQFVTLG
                     CTLVTLLANVRALYMRLWEINETEFIRCGCLIKNLPRTKAKSVVNDVEELGEIIDEDI
                     GNNVQENELVITSIPKPLTENCKKKKKRKKKNKSAIDGIFG"
     gene            complement(<432823..>433725)
                     /gene="SPE4"
                     /locus_tag="YLR146C"
                     /db_xref="GeneID:850838"
     mRNA            complement(<432823..>433725)
                     /gene="SPE4"
                     /locus_tag="YLR146C"
                     /product="spermine synthase"
                     /transcript_id="NM_001182033.1"
                     /db_xref="GI:296146676"
                     /db_xref="GeneID:850838"
     CDS             complement(432823..433725)
                     /gene="SPE4"
                     /locus_tag="YLR146C"
                     /EC_number="2.5.1.22"
                     /note="Spermine synthase; required for the biosynthesis of
                     spermine and also involved in biosynthesis of pantothenic
                     acid"
                     /codon_start=1
                     /product="spermine synthase"
                     /protein_id="NP_013247.1"
                     /db_xref="GI:6323175"
                     /db_xref="SGD:S000004136"
                     /db_xref="GeneID:850838"
                     /translation="MVNNSQHPYIKDGWFREINDKSFPGQAFTMTVDSILYEARSEFQ
                     DILIFRNKVYGTVLVLDGIVQCTEFDEFAYQEMITHIAMFAHSNPKRVLIIGGGDGGV
                     LREVAKHSCVEDITMVEIDSSVIELSRKFLPTLSNGAFDDERLDLKLCDGFKFLQDIG
                     ASDVHKKFDVIITDSSDPEGPAEAFFQERYFELLKDALNPNGVVIMQSSENFWLNLKY
                     LHDLKNTAKKVFPNTEYCYTMVPTYTSGQLGLIVCSNNANIPLNIPQRKISEQEQGKL
                     KYYNPQIHSSAFVLPTWADKVINE"
     gene            <433870..>434058
                     /locus_tag="YLR146W-A"
                     /db_xref="GeneID:3799977"
     mRNA            <433870..>434058
                     /locus_tag="YLR146W-A"
                     /product="hypothetical protein"
                     /transcript_id="NM_001184685.1"
                     /db_xref="GI:296146677"
                     /db_xref="GeneID:3799977"
     CDS             433870..434058
                     /locus_tag="YLR146W-A"
                     /codon_start=1
                     /product="hypothetical protein"
                     /protein_id="NP_001032582.1"
                     /db_xref="GI:82795259"
                     /db_xref="SGD:S000113566"
                     /db_xref="GeneID:3799977"
                     /translation="MDTEEKKKTTASVEHARMLQNEIQQLFAQLRDTNSQIRCDLNEF
                     EQIKESSTTADSTTNSAN"
     gene            complement(<434158..>434463)
                     /gene="SMD3"
                     /locus_tag="YLR147C"
                     /gene_synonym="SLT16"
                     /db_xref="GeneID:850839"
     mRNA            complement(<434158..>434463)
                     /gene="SMD3"
                     /locus_tag="YLR147C"
                     /gene_synonym="SLT16"
                     /product="Smd3p"
                     /transcript_id="NM_001182034.1"
                     /db_xref="GI:296146678"
                     /db_xref="GeneID:850839"
     CDS             complement(434158..434463)
                     /gene="SMD3"
                     /locus_tag="YLR147C"
                     /gene_synonym="SLT16"
                     /note="Core Sm protein Sm D3; part of heteroheptameric
                     complex (with Smb1p, Smd1p, Smd2p, Sme1p, Smx3p, and
                     Smx2p) that is part of the spliceosomal U1, U2, U4, and U5
                     snRNPs; homolog of human Sm D3"
                     /codon_start=1
                     /product="Smd3p"
                     /protein_id="NP_013248.1"
                     /db_xref="GI:6323176"
                     /db_xref="SGD:S000004137"
                     /db_xref="GeneID:850839"
                     /translation="MTMNGIPVKLLNEAQGHIVSLELTTGATYRGKLVESEDSMNVQL
                     RDVIATEPQGAVTHMDQIFVRGSQIKFIVVPDLLKNAPLFKKNSSRPMPPIRGPKRR"
     gene            <434641..>437397
                     /gene="PEP3"
                     /locus_tag="YLR148W"
                     /gene_synonym="VAM8; VPS18; VPT18"
                     /db_xref="GeneID:850840"
     mRNA            <434641..>437397
                     /gene="PEP3"
                     /locus_tag="YLR148W"
                     /gene_synonym="VAM8; VPS18; VPT18"
                     /product="Pep3p"
                     /transcript_id="NM_001182035.1"
                     /db_xref="GI:296146679"
                     /db_xref="GeneID:850840"
     CDS             434641..437397
                     /gene="PEP3"
                     /locus_tag="YLR148W"
                     /gene_synonym="VAM8; VPS18; VPT18"
                     /note="Component of CORVET membrane tethering complex;
                     vacuolar peripheral membrane protein that promotes
                     vesicular docking/fusion reactions in conjunction with
                     SNARE proteins, required for vacuolar biogenesis"
                     /codon_start=1
                     /product="Pep3p"
                     /protein_id="NP_013249.1"
                     /db_xref="GI:6323177"
                     /db_xref="SGD:S000004138"
                     /db_xref="GeneID:850840"
                     /translation="MIKTRIEEVQLQFLTGNTELTHLKVSNDQLIVTTQRTIYRINLQ
                     DPAIVNHFDCPLSKELETIMNVHVSPMGSVILIRTNFGRYMLLKDGEFTQLNKIKNLD
                     LSSLHWINETTFLMGIKKTPKLYRVELTGKDITTKLWYENKKLSGGIDGIAYWEGSLL
                     LTIKDNILYWRDVTNMKFPLVLPDESEQFERLKHHAIKKFDSYNGLFAWVTSNGIVFG
                     DLKEKQMEKDPASNNFGKFLSSSKVLLNFELPDYQNDKDHLIKDIVLTAFHILLLRKN
                     TVTMVSQLNNDVVFHETIPRHQLTGSNTDSNEKFLGLVRDSVKETFWCFSNINVFEII
                     IENEPNSVWNLLVRDNKFDKALSLKGLTVREIESVKLSKAMYLFHTAKDFHSAAQTLG
                     SMKDLSHFGEIALNFLQIKDYNDLNVILIKQLDNVPWKSTQVVLSSWIIWNFMKQLND
                     IELKINTTKPASTDEDNLLNWNLNLKEKSNELTKFLESHLEKLDNETVYQIMSKQNRQ
                     NELLIFASLINDMKFLLSFWIDQGNWYESLKILLTINNHDLVYKYSLILLLNSPEATV
                     STWMKIKDLDPNKLIPTILKFFTNWQNNSKLITNISEYPENYSLTYLKWCVREVPKMC
                     NPIVYNSILYMMITDPRNDMILENDIIKFMKSNENKYDLNFQLRLSLKFKKTKTSIFL
                     LTRLNLFEDAIDLALKNNLIDDCKVIVNDEILIEDYKLRKRLWLKIAKHLLLSMKDID
                     IKQLIRTILNDSNEILTIKDLLPFFNEYTTIANLKEELIKFLENHNMKMNEISEDIIN
                     SKNLKVEINTEISKFNEIYRILEPGKSCDECGKFLQIKKFIVFPCGHCFHWNCIIRVI
                     LNSNDYNLRQKTENFLKAKSKHNLNDLENIIVEKCGLCSDININKIDQPISIDETELA
                     KWNE"
     gene            complement(<437631..>439823)
                     /locus_tag="YLR149C"
                     /db_xref="GeneID:850841"
     mRNA            complement(<437631..>439823)
                     /locus_tag="YLR149C"
                     /product="hypothetical protein"
                     /transcript_id="NM_001182036.1"
                     /db_xref="GI:296146680"
                     /db_xref="GeneID:850841"
     CDS             complement(437631..439823)
                     /locus_tag="YLR149C"
                     /note="hypothetical protein; overexpression causes a cell
                     cycle delay or arrest; null mutation results in a decrease
                     in plasma membrane electron transport; YLR149C is not an
                     essential gene; protein abundance increases in response to
                     DNA replication stress"
                     /codon_start=1
                     /product="hypothetical protein"
                     /protein_id="NP_013250.1"
                     /db_xref="GI:6323178"
                     /db_xref="SGD:S000004139"
                     /db_xref="GeneID:850841"
                     /translation="MTIDGTGQSKEALQDERLNTGSDKVYQNYMMPALELYDAKVSIN
                     HWQLRDCIKPGSMNQSKLYYIYDHSIRVLDTDSSVLRSPVRRHNSIQPSNSGKNSTEK
                     TSTKGSRTTGSYISKNLHVPSEKLVEFNFKPRCFTELNGLTVCGGLIGSDDKGFPSNW
                     NRLAQDANISLPPPSQPINISKNISFPINSHYSNPNIWKGIVEFYNQETDTMMTFTLG
                     QFINNCVTLYDRASMQFDLFACNNDGHLYQCDVSNRDVTLVKRYADLKFPLNNASLSH
                     DGQTMVVSGDSNKFAVYNQNELTNQFSLHYDNHPSWGSSVNRVRRIPRFALPDESEYI
                     ENIYEAPNSDHGFYNSFSENDLQFATVFQNGTCAIYDIRNMATPMAEISSTRPHSHNG
                     AFRVCRFSYGLDDLLFISEHQGRVHVVDTRNYVNHQVIVIPDKVNMEYINERKHNTNH
                     NFTTNNNNENESNDSKNELQGADYRSLSRRRFSLPSMPNVTTEPWITMAQRIPKKYLE
                     PQILPFPKVMDKISNESVLFSTKGSSSSDVAHPYKRRCSFRVRRVSTSAPTADYSNNN
                     VNASLGTPAADSIATSSSNSAPQNLIDPLILSHQQASNDVFEDDEYYEAYNDVHSTYR
                     VSSDYHGVSARAFESFLRPPSTPDLPSDDDNFAANSRNNRGTSNFLRRPVITTQESNE
                     FSEENNISGIDWVEDRNGSSLIIGTDYGIMRWNINSWARRSFSSYDLC"
     gene            <440467..>441288
                     /gene="STM1"
                     /locus_tag="YLR150W"
                     /gene_synonym="MPT4"
                     /db_xref="GeneID:850843"
     mRNA            <440467..>441288
                     /gene="STM1"
                     /locus_tag="YLR150W"
                     /gene_synonym="MPT4"
                     /product="Stm1p"
                     /transcript_id="NM_001182037.1"
                     /db_xref="GI:296146681"
                     /db_xref="GeneID:850843"
     CDS             440467..441288
                     /gene="STM1"
                     /locus_tag="YLR150W"
                     /gene_synonym="MPT4"
                     /note="Protein required for optimal translation under
                     nutrient stress; perturbs association of Yef3p with
                     ribosomes; involved in TOR signaling; binds G4 quadruplex
                     and purine motif triplex nucleic acid; helps maintain
                     telomere structure; protein abundance increases in
                     response to DNA replication stress; serves as a ribosome
                     preservation factor both during quiescence and recovery"
                     /codon_start=1
                     /product="Stm1p"
                     /protein_id="NP_013251.1"
                     /db_xref="GI:6323179"
                     /db_xref="SGD:S000004140"
                     /db_xref="GeneID:850843"
                     /translation="MSNPFDLLGNDVEDADVVVLPPKEIVKSNTSSKKADVPPPSADP
                     SKARKNRPRPSGNEGAIRDKTAGRRNNRSKDVTDSATTKKSNTRRATDRHSRTGKTDT
                     KKKVNQGWGDDKKELSAEKEAQADAAAEIAEDAAEAEDAGKPKTAQLSLQDYLNQQAN
                     NQFNKVPEAKKVELDAERIETAEKEAYVPATKVKNVKSKQLKTKEYLEFDATFVESNT
                     RKNFGDRNNNSRNNFNNRRGGRGARKGNNTANATNSANTVQKNRNIDVSNLPSLA"
     gene            complement(<441715..>442737)
                     /gene="PCD1"
                     /locus_tag="YLR151C"
                     /db_xref="GeneID:850844"
     mRNA            complement(<441715..>442737)
                     /gene="PCD1"
                     /locus_tag="YLR151C"
                     /product="Pcd1p"
                     /transcript_id="NM_001182038.1"
                     /db_xref="GI:296146682"
                     /db_xref="GeneID:850844"
     CDS             complement(441715..442737)
                     /gene="PCD1"
                     /locus_tag="YLR151C"
                     /EC_number="3.6.1.55"
                     /note="8-oxo-dGTP diphosphatase; prevents spontaneous
                     mutagenesis via sanitization of oxidized purine nucleoside
                     triphosphates; can also act as peroxisomal pyrophosphatase
                     with specificity for coenzyme A and CoA derivatives, may
                     function to remove potentially toxic oxidized CoA
                     disulfide from peroxisomes to maintain the capacity for
                     beta-oxidation of fatty acids; nudix hydrolase family
                     member; similar E. coli MutT and human, rat and mouse
                     MTH1"
                     /codon_start=1
                     /product="Pcd1p"
                     /protein_id="NP_013252.1"
                     /db_xref="GI:6323180"
                     /db_xref="SGD:S000004141"
                     /db_xref="GeneID:850844"
                     /translation="MILSQRRMLSSKQLIENLIRYKFHKTPYTRSSIWPFKRNSAVII
                     LLFIGMKGELRVLLTKRSRTLRSFSGDVSFPGGKADYFQETFESVARREAEEEIGLPH
                     DPEVLHKEFGMKLDNLVMDMPCYLSRTFLSVKPMVCFLYKDKLEKHEDKYKVPLDIRK
                     FFGKLNPGETSSLFSVPLNDLVIHLLPEADEDVKSYQAEYFERKEYKLNWGGIKWLIM
                     HYHFHVANNNEMPWLQTIEDLSSSDEDGVDGGIFRFRDLWGLTCKILFDVSCIANGLM
                     DEKLKGELGHEDLIVGLHDYGNQMQPNGRSEWEIGMINGDRNLKYSDVIPEYYMKHLL
                     ECRSLW"
     gene            complement(<442958..>444688)
                     /locus_tag="YLR152C"
                     /db_xref="GeneID:850845"
     mRNA            complement(<442958..>444688)
                     /locus_tag="YLR152C"
                     /product="hypothetical protein"
                     /transcript_id="NM_001182039.1"
                     /db_xref="GI:296146683"
                     /db_xref="GeneID:850845"
     CDS             complement(442958..444688)
                     /locus_tag="YLR152C"
                     /note="hypothetical protein; YLR152C is not an essential
                     gene"
                     /codon_start=1
                     /product="hypothetical protein"
                     /protein_id="NP_013253.1"
                     /db_xref="GI:6323181"
                     /db_xref="SGD:S000004142"
                     /db_xref="GeneID:850845"
                     /translation="MSLSLGAAIYIALKPIFKIYTIMLVGYLVAKFDIVSMENAKGIS
                     NMVVNAILPCLTFNKIVSNISWRDIKEIGVIILSAFILFVLGATGALFTTFATTVPKK
                     FFWGLIFAGFFPNISDLPIAYIQSMGNGSIFTAEEADKGVAYSCIFLFIQSFLMMNFG
                     MWRVVGLDFRDTKEPDSENITPSVSPAIDDRKLTEITKLPNITRPTNAYQSEDARSNS
                     DLSCNSITTNEMTPQAFYEGFTGYIKPYKESNGASHKFESDLPHAEIYRVSSTYSSPG
                     ALEFSRIDGSSLSYSRISKNSDGRSYRRKRKADMNELISKYSAAEKIRQGELDLSRPL
                     SLTEEVGSRNASIGNVHTGYTDESSIEEENCTNMATDGRGSLSFFIERHNLKWLQYFI
                     INCLRPASLGAILGIICALIPWVKACFVTTYVHVHKAPDGEPVLNFLMDFTEYIGNAC
                     VPLGLLLLGGTLARLEIKSLPPGFIKSALLMTCFRLIVIPIIGVLWVNKLYSIDWLDT
                     GIGKFDMILTWSMPSATAQVYFTAFYTPACGDHIQMNCLSVLFVMQYAILFITVAFVV
                     TYTLKVDLKV"
     gene            complement(<445524..>447575)
                     /gene="ACS2"
                     /locus_tag="YLR153C"
                     /db_xref="GeneID:850846"
     mRNA            complement(<445524..>447575)
                     /gene="ACS2"
                     /locus_tag="YLR153C"
                     /product="acetate--CoA ligase ACS2"
                     /transcript_id="NM_001182040.1"
                     /db_xref="GI:296146684"
                     /db_xref="GeneID:850846"
     CDS             complement(445524..447575)
                     /gene="ACS2"
                     /locus_tag="YLR153C"
                     /EC_number="6.2.1.1"
                     /note="Acetyl-coA synthetase isoform; along with Acs1p,
                     acetyl-coA synthetase isoform is the nuclear source of
                     acetyl-coA for histone acetylation; mutants affect global
                     transcription; required for growth on glucose; expressed
                     under anaerobic conditions"
                     /codon_start=1
                     /product="acetate--CoA ligase ACS2"
                     /protein_id="NP_013254.1"
                     /db_xref="GI:6323182"
                     /db_xref="SGD:S000004143"
                     /db_xref="GeneID:850846"
                     /translation="MTIKEHKVVYEAHNVKALKAPQHFYNSQPGKGYVTDMQHYQEMY
                     QQSINEPEKFFDKMAKEYLHWDAPYTKVQSGSLNNGDVAWFLNGKLNASYNCVDRHAF
                     ANPDKPALIYEADDESDNKIITFGELLRKVSQIAGVLKSWGVKKGDTVAIYLPMIPEA
                     VIAMLAVARIGAIHSVVFAGFSAGSLKDRVVDANSKVVITCDEGKRGGKTINTKKIVD
                     EGLNGVDLVSRILVFQRTGTEGIPMKAGRDYWWHEEAAKQRTYLPPVSCDAEDPLFLL
                     YTSGSTGSPKGVVHTTGGYLLGAALTTRYVFDIHPEDVLFTAGDVGWITGHTYALYGP
                     LTLGTASIIFESTPAYPDYGRYWRIIQRHKATHFYVAPTALRLIKRVGEAEIAKYDTS
                     SLRVLGSVGEPISPDLWEWYHEKVGNKNCVICDTMWQTESGSHLIAPLAGAVPTKPGS
                     ATVPFFGINACIIDPVTGVELEGNDVEGVLAVKSPWPSMARSVWNHHDRYMDTYLKPY
                     PGHYFTGDGAGRDHDGYYWIRGRVDDVVNVSGHRLSTSEIEASISNHENVSEAAVVGI
                     PDELTGQTVVAYVSLKDGYLQNNATEGDAEHITPDNLRRELILQVRGEIGPFASPKTI
                     ILVRDLPRTRSGKIMRRVLRKVASNEAEQLGDLTTLANPEVVPAIISAVENQFFSQKK
                     K"
     gene            complement(<447982..>448314)
                     /gene="RNH203"
                     /locus_tag="YLR154C"
                     /db_xref="GeneID:850847"
     mRNA            complement(<447982..>448314)
                     /gene="RNH203"
                     /locus_tag="YLR154C"
                     /product="Rnh203p"
                     /transcript_id="NM_001182041.1"
                     /db_xref="GI:296146685"
                     /db_xref="GeneID:850847"
     CDS             complement(447982..448314)
                     /gene="RNH203"
                     /locus_tag="YLR154C"
                     /note="Ribonuclease H2 subunit; required for RNase H2
                     activity; role in ribonucleotide excision repair; related
                     to human AGS3 that causes Aicardi-Goutieres syndrome"
                     /codon_start=1
                     /product="Rnh203p"
                     /protein_id="NP_013255.1"
                     /db_xref="GI:6323183"
                     /db_xref="SGD:S000004144"
                     /db_xref="GeneID:850847"
                     /translation="MTKDAVNLDAYTVSFMPFYTEYQGPTEEFKDYKFEDTIYFRGKE
                     LKREKSATPSSSDNTTSNTFSNGAILSGNTITGKIVSVNNYEREGTDRNELARLQELI
                     SLIDVINQ"
     gene            complement(448650..448721)
                     /locus_tag="tQ(UUG)L"
                     /db_xref="GeneID:850848"
     tRNA            complement(448650..448721)
                     /locus_tag="tQ(UUG)L"
                     /product="tRNA-Gln"
                     /note="Glutamine tRNA (tRNA-Gln), predicted by tRNAscan-SE
                     analysis; thiolation of uridine at wobble position (34)
                     requires Ncs6p"
                     /db_xref="SGD:S000006699"
                     /db_xref="GeneID:850848"
     LTR             448842..449028
                     /note="Ty1 LTR"
                     /db_xref="SGD:S000007084"
     rep_origin      450485..450725
                     /note="ARS1216;
                     Autonomously Replicating Sequence"
                     /db_xref="SGD:S000118475"
     gene            complement(451575..458432)
                     /locus_tag="RDN37-1"
                     /db_xref="GeneID:9164931"
     rRNA            complement(451575..458432)
                     /locus_tag="RDN37-1"
                     /product="RDN37-1"
                     /note="35S ribosomal RNA (35S rRNA) transcript; encoded by
                     the RDN1 locus; processed into the 25S, 18S and 5.8S rRNAs
                     (represented by the RDN25, RDN18, and RDN58 loci)"
                     /db_xref="SGD:S000006486"
                     /db_xref="GeneID:9164931"
     gene            complement(451575..451785)
                     /locus_tag="ETS2-1"
                     /db_xref="GeneID:9164936"
     rRNA            complement(451575..451785)
                     /locus_tag="ETS2-1"
                     /product="ETS2-1"
                     /note="Non-coding region located adjacent to and
                     downstream of RDN25; transcribed as part of the 35S rRNA
                     precursor transcript; contains the primary rRNA
                     transcription termination site at +93 and a secondary
                     termination site between +211 and +250"
                     /db_xref="SGD:S000029718"
                     /db_xref="GeneID:9164936"
     gene            complement(451786..455181)
                     /locus_tag="RDN25-1"
                     /db_xref="GeneID:9164935"
     rRNA            complement(451786..455181)
                     /locus_tag="RDN25-1"
                     /product="RDN25-1"
                     /note="25S ribosomal RNA (25S rRNA); component of the
                     large (60S) ribosomal subunit; encoded in the rDNA repeat
                     (RDN1) as part of the 35S primary transcript; formed by
                     endonucleolytic cleavage at the C2 site of internal
                     transcribed spacer 2 (ITS2)"
                     /db_xref="SGD:S000006484"
                     /db_xref="GeneID:9164935"
     STS             452543..452960
                     /standard_name="Pp_Pp7"
                     /db_xref="UniSTS:259708"
     STS             452545..452997
                     /standard_name="PMC156610P1"
                     /db_xref="UniSTS:271418"
     STS             452695..453070
                     /standard_name="PMC133845P2"
                     /db_xref="UniSTS:270669"
     STS             452707..453001
                     /standard_name="PMC89798P1"
                     /db_xref="UniSTS:273611"
     STS             452745..453001
                     /standard_name="PMC89798P2"
                     /db_xref="UniSTS:273612"
     STS             452813..453060
                     /standard_name="PMC120649P1"
                     /db_xref="UniSTS:270380"
     STS             454422..455029
                     /standard_name="PMC316820P1"
                     /db_xref="UniSTS:273051"
     STS             454476..455113
                     /standard_name="PMC139893P1"
                     /db_xref="UniSTS:270904"
     STS             454574..454981
                     /standard_name="PMC60231P1"
                     /db_xref="UniSTS:273400"
     gene            <454696..>455070
                     /gene="TAR1"
                     /locus_tag="YLR154W-C"
                     /gene_synonym="YLR154W-A"
                     /db_xref="GeneID:1466405"
     mRNA            <454696..>455070
                     /gene="TAR1"
                     /locus_tag="YLR154W-C"
                     /gene_synonym="YLR154W-A"
                     /product="Tar1p"
                     /transcript_id="NM_001184514.1"
                     /db_xref="GI:296146686"
                     /db_xref="GeneID:1466405"
     CDS             454696..455070
                     /gene="TAR1"
                     /locus_tag="YLR154W-C"
                     /gene_synonym="YLR154W-A"
                     /note="Protein potentially involved in regulation of
                     respiratory metabolism; located in the mitochondria;
                     interacts genetically with RPO41 and physically with
                     Coq5p; encoded within the 25S rRNA gene on the opposite
                     strand"
                     /codon_start=1
                     /product="Tar1p"
                     /protein_id="NP_690845.1"
                     /db_xref="GI:23270399"
                     /db_xref="SGD:S000028422"
                     /db_xref="GeneID:1466405"
                     /translation="MRDSPTHKEQRAQNTMSDQMPFPFNNFTYFFTLFSKFFSSFHHC
                     TCSLSVSRQYLALDGIYHPLRAAFPNNSTLRRHFTKNRTPRHTGFSPSMTSCSKEHRQ
                     GTAPKLPSPNYNSGTEGTRFQI"
     STS             454949..455134
                     /standard_name="G28482"
                     /db_xref="UniSTS:48320"
     STS             455136..455976
                     /standard_name="PMC86038P1"
                     /db_xref="UniSTS:273512"
     gene            complement(455182..455413)
                     /locus_tag="ITS2-1"
                     /db_xref="GeneID:9164926"
     rRNA            complement(455182..455413)
                     /locus_tag="ITS2-1"
                     /product="ITS2-1"
                     /note="Non-coding region between RDN58 and RDN25;
                     transcribed as part of the 35S rRNA precursor transcript;
                     forms a stem-loop structure that is required for
                     processing of the precursor transcript"
                     /db_xref="SGD:S000029716"
                     /db_xref="GeneID:9164926"
     gene            complement(455414..455571)
                     /locus_tag="RDN58-1"
                     /db_xref="GeneID:9164934"
     rRNA            complement(455414..455571)
                     /locus_tag="RDN58-1"
                     /product="RDN58-1"
                     /note="5.8S ribosomal RNA (5.8S rRNA); component of the
                     large (60S) ribosomal subunit; encoded in the rDNA repeat
                     (RDN1) as part of the 35S primary transcript; 3' end
                     formation involves processing by the exosome complex while
                     5' end is generated by Kem1p and Rat1p"
                     /db_xref="SGD:S000006488"
                     /db_xref="GeneID:9164934"
     STS             455522..455974
                     /standard_name="ITS"
                     /db_xref="UniSTS:275294"
     gene            complement(455572..455932)
                     /locus_tag="ITS1-1"
                     /db_xref="GeneID:9164938"
     rRNA            complement(455572..455932)
                     /locus_tag="ITS1-1"
                     /product="ITS1-1"
                     /note="Non-coding region between RDN58 and RDN18;
                     transcribed as part of the 35S rRNA precursor transcript;
                     excision during transcript maturation is coupled with
                     processing of the 3' external transcribed spacer (3'ETS)"
                     /db_xref="SGD:S000029715"
                     /db_xref="GeneID:9164938"
     STS             455589..455685
                     /standard_name="PMC140538P1"
                     /db_xref="UniSTS:270941"
     STS             455729..455928
                     /standard_name="PMC316945P1"
                     /db_xref="UniSTS:273065"
     gene            complement(455933..457732)
                     /locus_tag="RDN18-1"
                     /db_xref="GeneID:9164923"
     rRNA            complement(455933..457732)
                     /locus_tag="RDN18-1"
                     /product="RDN18-1"
                     /note="18S ribosomal RNA (18S rRNA); component of the
                     small (40S) ribosomal subunit; involved in codon
                     recognition by tRNAs or the release factor eRF1 (Sup45p);
                     encoded in the rDNA repeat (RDN1) as part of the 35S
                     primary transcript"
                     /db_xref="SGD:S000006482"
                     /db_xref="GeneID:9164923"
     STS             456426..456720
                     /standard_name="PMC84574P1"
                     /db_xref="UniSTS:273448"
     STS             456487..457457
                     /standard_name="PMC140342P1"
                     /db_xref="UniSTS:270933"
     STS             456533..457329
                     /standard_name="PMC343294P1"
                     /db_xref="UniSTS:273189"
     STS             456624..456974
                     /standard_name="PMC133845P3"
                     /db_xref="UniSTS:270670"
     STS             456686..457188
                     /standard_name="PMC104890P1"
                     /db_xref="UniSTS:270115"
     STS             456721..456797
                     /standard_name="PMC152246P1"
                     /db_xref="UniSTS:271203"
     STS             456732..457417
                     /standard_name="PMC95223P1"
                     /db_xref="UniSTS:273623"
     STS             456783..457302
                     /standard_name="PMC125238P1"
                     /db_xref="UniSTS:270483"
     STS             456862..457276
                     /standard_name="PMC87142P1"
                     /db_xref="UniSTS:273581"
     STS             457160..457713
                     /standard_name="PMC106412P1"
                     /db_xref="UniSTS:270119"
     gene            complement(457733..458432)
                     /locus_tag="ETS1-1"
                     /db_xref="GeneID:9164941"
     rRNA            complement(457733..458432)
                     /locus_tag="ETS1-1"
                     /product="ETS1-1"
                     /note="Non-coding region located immediately upstream of
                     RDN18; transcribed as part of the 35S rRNA precursor
                     transcript; contains an essential U3 snoRNA binding site
                     required for maturation of 18S rRNA"
                     /db_xref="SGD:S000029717"
                     /db_xref="GeneID:9164941"
     STS             458142..459015
                     /standard_name="ha3107"
                     /db_xref="UniSTS:515651"
     gene            complement(458433..459675)
                     /locus_tag="NTS2-1"
                     /db_xref="GeneID:9164919"
     rRNA            complement(458433..459675)
                     /locus_tag="NTS2-1"
                     /product="NTS2-1"
                     /note="Nontranscribed region of the rDNA repeat; located
                     between RND5 and the 5'ETS; contains RNA polymerase I
                     termination site"
                     /db_xref="SGD:S000029329"
                     /db_xref="GeneID:9164919"
     rep_origin      458991..459097
                     /note="ARS1200-1;
                     Chromosomal origin of bidirectional DNA replication; an
                     rDNA ARS is presumed to be present in each tandem rDNA
                     repeat, but fewer than one-third of the rDNA ARSs are
                     actually used as replication origins in a given S phase"
                     /db_xref="SGD:S000120636"
     STS             459662..459788
                     /standard_name="PMC99952P1"
                     /db_xref="UniSTS:273710"
     gene            459676..459796
                     /locus_tag="RDN5-1"
                     /db_xref="GeneID:9164945"
     rRNA            459676..459796
                     /locus_tag="RDN5-1"
                     /product="RDN5-1"
                     /note="5S ribosomal RNA (5S rRNA); only complete sequence
                     of 6 repeated RDN5 alleles; able to support viability when
                     provided as sole form of 5S rRNA; component of the large
                     (60S) ribosomal subunit; localized to the nucleolus via
                     interaction with Rpl5p; may play a role in translational
                     frame fidelity; transcription is mediated by PolIII and
                     activated by TFIIIA and TFIIIE"
                     /db_xref="SGD:S000006479"
                     /db_xref="GeneID:9164945"
     gene            complement(459797..460711)
                     /locus_tag="NTS1-2"
                     /db_xref="GeneID:9164943"
     rRNA            complement(459797..460711)
                     /locus_tag="NTS1-2"
                     /product="NTS1-2"
                     /note="Non-transcribed region of the rDNA repeat between
                     the 3' ETS and RDN5; required for rDNA repeat expansion"
                     /db_xref="SGD:S000029714"
                     /db_xref="GeneID:9164943"
     STS             459985..460291
                     /standard_name="PMC133845P1"
                     /db_xref="UniSTS:270668"
     gene            complement(460712..467569)
                     /locus_tag="RDN37-2"
                     /db_xref="GeneID:9164920"
     rRNA            complement(460712..467569)
                     /locus_tag="RDN37-2"
                     /product="RDN37-2"
                     /note="35S ribosomal RNA (35S rRNA) transcript; encoded by
                     the RDN1 locus; processed into the 25S, 18S and 5.8S rRNAs
                     (represented by the RDN25, RDN18, and RDN58 loci)"
                     /db_xref="SGD:S000006487"
                     /db_xref="GeneID:9164920"
     gene            complement(460712..460922)
                     /locus_tag="ETS2-2"
                     /db_xref="GeneID:9164942"
     rRNA            complement(460712..460922)
                     /locus_tag="ETS2-2"
                     /product="ETS2-2"
                     /note="Non-coding region located adjacent to RDN25;
                     transcribed as part of the 35S rRNA precursor transcript;
                     contains the primary rRNA transcription termination site
                     at +93 and a secondary termination site between +211 and
                     +250"
                     /db_xref="SGD:S000029713"
                     /db_xref="GeneID:9164942"
     gene            complement(460923..464318)
                     /locus_tag="RDN25-2"
                     /db_xref="GeneID:9164921"
     rRNA            complement(460923..464318)
                     /locus_tag="RDN25-2"
                     /product="RDN25-2"
                     /note="25S ribosomal RNA (25S rRNA); component of the
                     large (60S) ribosomal subunit; encoded in the rDNA repeat
                     (RDN1) as part of the 35S primary transcript; formed by
                     endonucleolytic cleavage at the C2 site of internal
                     transcribed spacer 2 (ITS2)"
                     /db_xref="SGD:S000006485"
                     /db_xref="GeneID:9164921"
     STS             461680..462097
                     /standard_name="Pp_Pp7"
                     /db_xref="UniSTS:259708"
     STS             461682..462134
                     /standard_name="PMC156610P1"
                     /db_xref="UniSTS:271418"
     STS             461832..462207
                     /standard_name="PMC133845P2"
                     /db_xref="UniSTS:270669"
     STS             461844..462138
                     /standard_name="PMC89798P1"
                     /db_xref="UniSTS:273611"
     STS             461882..462138
                     /standard_name="PMC89798P2"
                     /db_xref="UniSTS:273612"
     STS             461950..462197
                     /standard_name="PMC120649P1"
                     /db_xref="UniSTS:270380"
     gene            complement(<462522..>462671)
                     /locus_tag="YLR154C-G"
                     /db_xref="GeneID:1466409"
     mRNA            complement(<462522..>462671)
                     /locus_tag="YLR154C-G"
                     /product="hypothetical protein"
                     /transcript_id="NM_001184560.1"
                     /db_xref="GI:296146687"
                     /db_xref="GeneID:1466409"
     CDS             complement(462522..462671)
                     /locus_tag="YLR154C-G"
                     /note="hypothetical protein; identified by fungal homology
                     comparisons and RT-PCR; this ORF is contained within
                     RDN25-2 and RDN37-2"
                     /codon_start=1
                     /product="hypothetical protein"
                     /protein_id="NP_878121.1"
                     /db_xref="GI:33438833"
                     /db_xref="SGD:S000028561"
                     /db_xref="GeneID:1466409"
                     /translation="MWRRRREPWEELSFLLNSLSPRNWFIRRWGLMAGRGQHLCWLRC
                     ACDGP"
     STS             463559..464166
                     /standard_name="PMC316820P1"
                     /db_xref="UniSTS:273051"
     STS             463613..464250
                     /standard_name="PMC139893P1"
                     /db_xref="UniSTS:270904"
     STS             463711..464118
                     /standard_name="PMC60231P1"
                     /db_xref="UniSTS:273400"
     STS             464086..464271
                     /standard_name="G28482"
                     /db_xref="UniSTS:48320"
     STS             464273..465113
                     /standard_name="PMC86038P1"
                     /db_xref="UniSTS:273512"
     gene            complement(464319..464550)
                     /locus_tag="ITS2-2"
                     /db_xref="GeneID:9164930"
     rRNA            complement(464319..464550)
                     /locus_tag="ITS2-2"
                     /product="ITS2-2"
                     /note="Non-coding region between RDN58 and RDN25;
                     transcribed as part of the 35S rRNA precursor transcript;
                     forms a stem-loop structure required for processing of the
                     precursor transcript"
                     /db_xref="SGD:S000029712"
                     /db_xref="GeneID:9164930"
     gene            complement(464551..464708)
                     /locus_tag="RDN58-2"
                     /db_xref="GeneID:9164939"
     rRNA            complement(464551..464708)
                     /locus_tag="RDN58-2"
                     /product="RDN58-2"
                     /note="5.8S ribosomal RNA (5.8S rRNA); component of the
                     large (60S) ribosomal subunit; encoded in the rDNA repeat
                     (RDN1)"
                     /db_xref="SGD:S000006489"
                     /db_xref="GeneID:9164939"
     STS             464659..465111
                     /standard_name="ITS"
                     /db_xref="UniSTS:275294"
     gene            complement(464709..465069)
                     /locus_tag="ITS1-2"
                     /db_xref="GeneID:9164940"
     rRNA            complement(464709..465069)
                     /locus_tag="ITS1-2"
                     /product="ITS1-2"
                     /note="Non-coding region between RDN58 and RDN18;
                     transcribed as part of the 35S rRNA precursor transcript;
                     excision during transcript maturation is coupled with
                     processing of the 3' external transcribed spacer (3' ETS)"
                     /db_xref="SGD:S000029709"
                     /db_xref="GeneID:9164940"
     STS             464726..464822
                     /standard_name="PMC140538P1"
                     /db_xref="UniSTS:270941"
     STS             464866..465065
                     /standard_name="PMC316945P1"
                     /db_xref="UniSTS:273065"
     gene            complement(465070..466869)
                     /locus_tag="RDN18-2"
                     /db_xref="GeneID:9164932"
     rRNA            complement(465070..466869)
                     /locus_tag="RDN18-2"
                     /product="RDN18-2"
                     /note="18S ribosomal RNA (18S rRNA); component of the
                     small (40S) ribosomal subunit; involved in codon
                     recognition by tRNAs or the release factor eRF1 (Sup45p);
                     encoded in the rDNA repeat (RDN1) as part of the 35S
                     primary transcript"
                     /db_xref="SGD:S000006483"
                     /db_xref="GeneID:9164932"
     STS             465563..465857
                     /standard_name="PMC84574P1"
                     /db_xref="UniSTS:273448"
     STS             465624..466594
                     /standard_name="PMC140342P1"
                     /db_xref="UniSTS:270933"
     STS             465670..466466
                     /standard_name="PMC343294P1"
                     /db_xref="UniSTS:273189"
     STS             465761..466111
                     /standard_name="PMC133845P3"
                     /db_xref="UniSTS:270670"
     STS             465823..466325
                     /standard_name="PMC104890P1"
                     /db_xref="UniSTS:270115"
     STS             465858..465934
                     /standard_name="PMC152246P1"
                     /db_xref="UniSTS:271203"
     STS             465869..466554
                     /standard_name="PMC95223P1"
                     /db_xref="UniSTS:273623"
     STS             465920..466439
                     /standard_name="PMC125238P1"
                     /db_xref="UniSTS:270483"
     STS             465999..466413
                     /standard_name="PMC87142P1"
                     /db_xref="UniSTS:273581"
     STS             466297..466850
                     /standard_name="PMC106412P1"
                     /db_xref="UniSTS:270119"
     gene            complement(466870..467569)
                     /locus_tag="ETS1-2"
                     /db_xref="GeneID:9164933"
     rRNA            complement(466870..467569)
                     /locus_tag="ETS1-2"
                     /product="ETS1-2"
                     /note="Non-coding region located immediately upstream of
                     RDN18; transcribed as part of the 35S rRNA precursor
                     transcript; contains an essential U3 snoRNA binding site
                     required for maturation of 18S rRNA"
                     /db_xref="SGD:S000029707"
                     /db_xref="GeneID:9164933"
     STS             467279..468152
                     /standard_name="ha3107"
                     /db_xref="UniSTS:515651"
     gene            complement(467570..468812)
                     /locus_tag="NTS2-2"
                     /db_xref="GeneID:9164948"
     rRNA            complement(467570..468812)
                     /locus_tag="NTS2-2"
                     /product="NTS2-2"
                     /note="Non-transcribed region of the rDNA repeat; located
                     between RDN5 and the 5' ETS"
                     /db_xref="SGD:S000029706"
                     /db_xref="GeneID:9164948"
     rep_origin      468128..468234
                     /note="ARS1200-2;
                     Chromosomal origin of bidirectional DNA replication; an
                     rDNA ARS is presumed to be present in each tandem rDNA
                     repeat, but fewer than one-third of the rDNA ARSs are
                     actually used as replication origins in a given S phase"
                     /db_xref="SGD:S000120655"
     STS             468799..468925
                     /standard_name="PMC99952P1"
                     /db_xref="UniSTS:273710"
     gene            468813..468931
                     /locus_tag="RDN5-2"
                     /db_xref="GeneID:9164928"
     rRNA            468813..468931
                     /locus_tag="RDN5-2"
                     /product="RDN5-2"
                     /note="Variant 5S ribosomal rRNA (5S rRNA) gene; located
                     within the RDN1 locus; unable to support cell viability
                     when provided as sole source of 5S rRNA; identical in
                     sequence to variant alleles RDN5-3, RDN5-4, and RDN5-5"
                     /db_xref="SGD:S000006480"
                     /db_xref="GeneID:9164928"
     gene            complement(<468827..>468958)
                     /locus_tag="YLR154C-H"
                     /db_xref="GeneID:1466410"
     mRNA            complement(<468827..>468958)
                     /locus_tag="YLR154C-H"
                     /product="hypothetical protein"
                     /transcript_id="NM_001184564.1"
                     /db_xref="GI:296146697"
                     /db_xref="GeneID:1466410"
     CDS             complement(468827..468958)
                     /locus_tag="YLR154C-H"
                     /note="hypothetical protein; identified by fungal homology
                     comparisons and RT-PCR; this ORF partially overlaps
                     RDN5-2; YLR154C-H has a paralog, YLR157C-C, that arose
                     from a segmental duplication"
                     /codon_start=1
                     /product="hypothetical protein"
                     /protein_id="NP_878126.1"
                     /db_xref="GI:33438838"
                     /db_xref="SGD:S000028562"
                     /db_xref="GeneID:1466410"
                     /translation="MYSCAKKKTTAAPEFRVWSPTTLLGQALTSLTTVDRTGNGAFW"
     gene            complement(<469317..>470405)
                     /gene="ASP3-1"
                     /locus_tag="YLR155C"
                     /gene_synonym="ASP3"
                     /db_xref="GeneID:850850"
     mRNA            complement(<469317..>470405)
                     /gene="ASP3-1"
                     /locus_tag="YLR155C"
                     /gene_synonym="ASP3"
                     /product="asparaginase ASP3-1"
                     /transcript_id="NM_001182042.1"
                     /db_xref="GI:296146689"
                     /db_xref="GeneID:850850"
     CDS             complement(469317..470405)
                     /gene="ASP3-1"
                     /locus_tag="YLR155C"
                     /gene_synonym="ASP3"
                     /EC_number="3.5.1.1"
                     /note="Cell-wall L-asparaginase II involved in asparagine
                     catabolism; expression induced during nitrogen starvation;
                     ORF contains a short non-coding RNA that enhances
                     expression of full-length gene; likely arose in via
                     horizontal gene transfer from the wine yeast
                     Wickerhamomyces anomalus or a close relative; reference
                     strain S288C has four copies of ASP3; ASP3-1 has a
                     paralog, ASP3-3, that arose from a segmental duplication"
                     /codon_start=1
                     /product="asparaginase ASP3-1"
                     /protein_id="NP_013256.1"
                     /db_xref="GI:6323184"
                     /db_xref="SGD:S000004145"
                     /db_xref="GeneID:850850"
                     /translation="MRSLNTLLLSLFVAMSSGAPLLKIREEKNSSLPSIKIFGTGGTI
                     ASKGSTSATTAGYSVGLTVNDLIEAVPSLAEKANLDYLQVSNVGSNSLNYTHLIPLYH
                     GISEALASDDYAGAVVTHGTDTMEETAFFLDLTINSEKPVCIAGAMRPATATSADGPM
                     NLYQAVSIAASEKSLGRGTMITLNDRIASGFWTTKMNANSLDTFRADEQGYLGYFSND
                     DVEFYYPPVKPNGWQFFDISNLTDPSEIPEVIILYSYQGLNPELIVKAVKDLGAKGIV
                     LAGSGAGSWTATGSIVNEQLYEEYGIPIVHSRRTADGTVPPDDAPEYAIGSGYLNPQK
                     SRILLQLCLYSGYGMDQIRSVFSGVYGG"
     gene            <472113..>472457
                     /locus_tag="YLR156W"
                     /db_xref="GeneID:850851"
     mRNA            <472113..>472457
                     /locus_tag="YLR156W"
                     /product="hypothetical protein"
                     /transcript_id="NM_001182043.1"
                     /db_xref="GI:296146690"
                     /db_xref="GeneID:850851"
     CDS             472113..472457
                     /locus_tag="YLR156W"
                     /note="hypothetical protein; exhibits a two-hybrid
                     interaction with Jsn1p in a large-scale analysis; YLR156W
                     has a paralog, YLR159W, that arose from a segmental
                     duplication"
                     /codon_start=1
                     /product="hypothetical protein"
                     /protein_id="NP_757337.1"
                     /db_xref="GI:26225099"
                     /db_xref="SGD:S000004146"
                     /db_xref="GeneID:850851"
                     /translation="MKFQYALAKEQLGSNSRSGVKKLISKHHWLPEYYFSDLSFSVVQ
                     QWDSRAIEKTTIISCMRPANQEIYPLRHCETLRSQPCSLFSSLYARSFQSSCTLHVAE
                     PSPGFHMYGCHT"
     gene            472465..472583
                     /locus_tag="RDN5-3"
                     /db_xref="GeneID:9164924"
     rRNA            472465..472583
                     /locus_tag="RDN5-3"
                     /product="RDN5-3"
                     /note="Variant 5S ribosomal RNA (5S rRNA) gene; located at
                     a site distal to the RDN1 locus; unable to support cell
                     viability when provided as sole source of 5S rRNA;
                     identical in sequence to variant alleles RDN5-2, RDN5-4,
                     and RDN5-5"
                     /db_xref="SGD:S000006481"
                     /db_xref="GeneID:9164924"
     gene            complement(<472479..>472610)
                     /locus_tag="YLR156C-A"
                     /db_xref="GeneID:1466411"
     mRNA            complement(<472479..>472610)
                     /locus_tag="YLR156C-A"
                     /product="hypothetical protein"
                     /transcript_id="NM_001184563.1"
                     /db_xref="GI:296146691"
                     /db_xref="GeneID:1466411"
     CDS             complement(472479..472610)
                     /locus_tag="YLR156C-A"
                     /note="hypothetical protein; identified by fungal homology
                     comparisons and RT-PCR; partially overlaps RND5-3;
                     YLR156C-A has a paralog, YLR159C-A, that arose from a
                     segmental duplication"
                     /codon_start=1
                     /product="hypothetical protein"
                     /protein_id="NP_878123.1"
                     /db_xref="GI:33438835"
                     /db_xref="SGD:S000028564"
                     /db_xref="GeneID:1466411"
                     /translation="MYSCAKKKTTAAPEFRVWSPTTLLGQALTSLTTVDRTGNGAFW"
     gene            complement(<472969..>474057)
                     /gene="ASP3-2"
                     /locus_tag="YLR157C"
                     /gene_synonym="ASP3"
                     /db_xref="GeneID:850852"
     mRNA            complement(<472969..>474057)
                     /gene="ASP3-2"
                     /locus_tag="YLR157C"
                     /gene_synonym="ASP3"
                     /product="asparaginase ASP3-2"
                     /transcript_id="NM_001182044.1"
                     /db_xref="GI:296146692"
                     /db_xref="GeneID:850852"
     CDS             complement(472969..474057)
                     /gene="ASP3-2"
                     /locus_tag="YLR157C"
                     /gene_synonym="ASP3"
                     /EC_number="3.5.1.1"
                     /note="Cell-wall L-asparaginase II involved in asparagine
                     catabolism; expression induced during nitrogen starvation;
                     ORF contains a short non-coding RNA that enhances
                     expression of full-length gene; likely arose in via
                     horizontal gene transfer from the wine yeast
                     Wickerhamomyces anomalus or a close relative; reference
                     strain S288C has four copies of ASP3; ASP3-2 has a
                     paralog, ASP3-4, that arose from a segmental duplication"
                     /codon_start=1
                     /product="asparaginase ASP3-2"
                     /protein_id="NP_013258.1"
                     /db_xref="GI:6323186"
                     /db_xref="SGD:S000004147"
                     /db_xref="GeneID:850852"
                     /translation="MRSLNTLLLSLFVAMSSGAPLLKIREEKNSSLPSIKIFGTGGTI
                     ASKGSTSATTAGYSVGLTVNDLIEAVPSLAEKANLDYLQVSNVGSNSLNYTHLIPLYH
                     GISEALASDDYAGAVVTHGTDTMEETAFFLDLTINSEKPVCIAGAMRPATATSADGPM
                     NLYQAVSIAASEKSLGRGTMITLNDRIASGFWTTKMNANSLDTFRADEQGYLGYFSND
                     DVEFYYPPVKPNGWQFFDISNLTDPSEIPEVIILYSYQGLNPELIVKAVKDLGAKGIV
                     LAGSGAGSWTATGSIVNEQLYEEYGIPIVHSRRTADGTVPPDDAPEYAIGSGYLNPQK
                     SRILLQLCLYSGYGMDQIRSVFSGVYGG"
     gene            <475764..>475976
                     /locus_tag="YLR157W-D"
                     /gene_synonym="YLR157W-A"
                     /db_xref="GeneID:1466412"
     mRNA            <475764..>475976
                     /locus_tag="YLR157W-D"
                     /gene_synonym="YLR157W-A"
                     /product="hypothetical protein"
                     /transcript_id="NM_001184608.1"
                     /db_xref="GI:296146693"
                     /db_xref="GeneID:1466412"
     CDS             475764..475976
                     /locus_tag="YLR157W-D"
                     /gene_synonym="YLR157W-A"
                     /note="hypothetical protein; identified by gene-trapping,
                     microarray-based expression analysis, and genome-wide
                     homology searching; YLR157W-D has a paralog, YLR161W, that
                     arose from a segmental duplication"
                     /codon_start=1
                     /product="hypothetical protein"
                     /protein_id="NP_878124.1"
                     /db_xref="GI:33438836"
                     /db_xref="SGD:S000028677"
                     /db_xref="GeneID:1466412"
                     /translation="MKFQYALAKEQLGSNSRSGVKKLISKHHWLPEYYFSDLSFSVVQ
                     QWDSRAIEKTTIISCMRPANQEIYPL"
     mobile_element  complement(475976..481897)
                     /note="YLRCTy1-1; Ty1 element, LTR retrotransposon of the
                     Copia (Pseudoviridae) group; contains co-transcribed genes
                     TYA Gag and TYB Pol, encoding proteins involved in
                     structure and function of virus-like particles, flanked by
                     two direct repeats"
                     /mobile_element_type="retrotransposon:YLRCTy1-1"
                     /db_xref="SGD:S000007081"
     LTR             complement(475976..476310)
                     /note="Ty1 LTR"
                     /db_xref="SGD:S000007068"
     gene            complement(<476333..>481601)
                     /locus_tag="YLR157C-B"
                     /db_xref="GeneID:850853"
     mRNA            complement(join(<476333..480295,480297..>481601))
                     /locus_tag="YLR157C-B"
                     /product="gag-pol fusion protein"
                     /transcript_id="NM_001184406.1"
                     /db_xref="GI:296146694"
                     /db_xref="GeneID:850853"
     CDS             complement(join(476333..480295,480297..481601))
                     /locus_tag="YLR157C-B"
                     /EC_number="3.4.23.-"
                     /EC_number="3.1.26.4"
                     /EC_number="2.7.7.7"
                     /EC_number="2.7.7.49"
                     /ribosomal_slippage
                     /note="Retrotransposon TYA Gag and TYB Pol genes;
                     transcribed/translated as one unit; polyprotein is
                     processed to make a nucleocapsid-like protein (Gag),
                     reverse transcriptase (RT), protease (PR), and integrase
                     (IN); similar to retroviral genes"
                     /codon_start=1
                     /product="gag-pol fusion protein"
                     /protein_id="NP_058169.1"
                     /db_xref="GI:7839185"
                     /db_xref="SGD:S000007374"
                     /db_xref="GeneID:850853"
                     /translation="MESQQLSQHSPISHGSACASVTSKEVHTNQDPLDVSASKTEECE
                     KASTKANSQQTTTPASSAVPENPHHASPQPASVPPPQNGPYPQQCMMTQNQANPSGWS
                     FYGHPSMIPYTPYQMSPMYFPPGPQSQFPQYPSSVGTPLSTPSPESGNTFTDSSSADS
                     DMTSTKKYVRPPPMLTSPNDFPNWVKTYIKFLQNSNLGGIIPTVNGKPVRQITDDELT
                     FLYNTFQIFAPSQFLPTWVKDILSVDYTDIMKILSKSIEKMQSDTQEANDIVTLANLQ
                     YNGSTPADAFETKVTNIIDRLNNNGIHINNKVACQLIMRGLSGEYKFLRYTRHRHLNM
                     TVAELFLDIHAIYEEQQGSRNSKPNYRRNLSDEKNDSRSYTNTTKPKVIARNPQKTNN
                     SKSKTARAHNVSTSNNSPSTDNDSISKSTTEPIQLNNKHDLHLGQELTESTVNHTNHS
                     DDELPGHLLLDSGASRTLIRSAHHIHSASSNPDINVVDAQKRNIPINAIGDLQFHFQD
                     NTKTSIKVLHTPNIAYDLLSLNELAAVDITACFTKNVLERSDGTVLAPIVKYGDFYWV
                     SKKYLLPSNISVPTINNVHTSESTRKYPYPFIHRMLAHANAPTIRYSLKNNTITYFNE
                     SDVDWSSAIDYQCPDCLIGKSTKHRHIKGSRLKYQNSYEPFQYLHTDIFGPVHNLPNS
                     APSYFISFTDETTKFRWVYPLHDRREDSILDVFTTILAFIKNQFQASVLVIQMDRGSE
                     YTNRTLHKFLEKNGITPCYTTTADSRAHGVAERLNRTLLDDCRTQLQCSGLPNHLWFS
                     AIEFSTIVRNSLASPKSKKSARQHAGLAGLDISTLLPFGQPVIVNDHNPNSKIHPRGI
                     PGYALHPSRNSYGYIIYLPSLKKTVDTTNYVILQGKESRLDQFNYDALTFDEDLNRLT
                     ASYHSFIASNEIQESNDLNIESDHDFQSDIELHPEQPRNVLSKAVSPTDSTPPSTHTE
                     DSKRVSKTNIRAPREVDPNISESNILPSKKRSSTPQISNIESTGSGGMHKLNVPLLAP
                     MSQSNTHESSHASKSKDFRHSDSYSENETNHTNVPISSTGGTNNKTVPQISDQETEKR
                     IIHRSPSIDASPPENNSSHNIVPIKTPTTVSEQNTEESIIADLPLPDLPPESPTEFPD
                     PFKELPPINSRQTNSSLGGIGDSNAYTTINSKKRSLEDNETEIKVSRDTWNTKNMRSL
                     EPPRSKKRIHLIAAVKAVKSIKPIRTTLRYDEAITYNKDIKEKEKYIEAYHKEVNQLL
                     KMKTWDTDEYYDRKEIDPKRVINSMFIFNKKRDGTHKARFVARGDIQHPDTYDSGMQS
                     NTVHHYALMTSLSLALDNNYYITQLDISSAYLYADIKEELYIRPPPHLGMNDKLIRLK
                     KSLYGLKQSGANWYETIKSYLIKQCGMEEVRGWSCVFKNSQVTICLFVDDMILFSKDL
                     NANKKIITTLKKQYDTKIINLGESDNEIQYDILGLEIKYQRGKYMKLGMENSLTEKIP
                     KLNVPLNPKGRKLSAPGQPGLYIDQDELEIDEDEYKEKVHEMQKLIGLASYVGYKFRF
                     DLLYYINTLAQHILFPSRQVLDMTYELIQFMWDTRDKQLIWHKNKPTEPDNKLVAISD
                     ASYGNQPYYKSQIGNIYLLNGKVIGGKSTKASLTCTSTTEAEIHAISESVPLLNNLSY
                     LIQELNKKPIIKGLLTDSRSTISIIKSTNEEKFRNRFFGTKAMRLRDEVSGNNLYVYY
                     IETKKNIADVMTKPLPIKTFKLLTNKWIH"
     gene            complement(<480279..>481601)
                     /locus_tag="YLR157C-A"
                     /db_xref="GeneID:850854"
     mRNA            complement(<480279..>481601)
                     /locus_tag="YLR157C-A"
                     /product="gag protein"
                     /transcript_id="NM_001184405.1"
                     /db_xref="GI:296146695"
                     /db_xref="GeneID:850854"
     CDS             complement(480279..481601)
                     /locus_tag="YLR157C-A"
                     /note="Retrotransposon TYA Gag gene co-transcribed with
                     TYB Pol; translated as TYA or TYA-TYB polyprotein; Gag is
                     a nucleocapsid protein that is the structural constituent
                     of virus-like particles (VLPs); similar to retroviral Gag"
                     /codon_start=1
                     /product="gag protein"
                     /protein_id="NP_058170.1"
                     /db_xref="GI:7839184"
                     /db_xref="SGD:S000007373"
                     /db_xref="GeneID:850854"
                     /translation="MESQQLSQHSPISHGSACASVTSKEVHTNQDPLDVSASKTEECE
                     KASTKANSQQTTTPASSAVPENPHHASPQPASVPPPQNGPYPQQCMMTQNQANPSGWS
                     FYGHPSMIPYTPYQMSPMYFPPGPQSQFPQYPSSVGTPLSTPSPESGNTFTDSSSADS
                     DMTSTKKYVRPPPMLTSPNDFPNWVKTYIKFLQNSNLGGIIPTVNGKPVRQITDDELT
                     FLYNTFQIFAPSQFLPTWVKDILSVDYTDIMKILSKSIEKMQSDTQEANDIVTLANLQ
                     YNGSTPADAFETKVTNIIDRLNNNGIHINNKVACQLIMRGLSGEYKFLRYTRHRHLNM
                     TVAELFLDIHAIYEEQQGSRNSKPNYRRNLSDEKNDSRSYTNTTKPKVIARNPQKTNN
                     SKSKTARAHNVSTSNNSPSTDNDSISKSTTEPIQLNNKHDLHLRPGTY"
     LTR             complement(481563..481897)
                     /note="Ty1 LTR"
                     /db_xref="SGD:S000007069"
     gene            <481873..>482037
                     /locus_tag="YLR157W-E"
                     /gene_synonym="YLR157W-B; YLR157W-C"
                     /db_xref="GeneID:1466413"
     mRNA            <481873..>482037
                     /locus_tag="YLR157W-E"
                     /gene_synonym="YLR157W-B; YLR157W-C"
                     /product="hypothetical protein"
                     /transcript_id="NM_001184609.1"
                     /db_xref="GI:296146696"
                     /db_xref="GeneID:1466413"
     CDS             481873..482037
                     /locus_tag="YLR157W-E"
                     /gene_synonym="YLR157W-B; YLR157W-C"
                     /note="hypothetical protein identified by gene-trapping;
                     microarray-based expression analysis, and genome-wide
                     homology searching; partially overlaps a Ty1 element"
                     /codon_start=1
                     /product="hypothetical protein"
                     /protein_id="NP_878125.1"
                     /db_xref="GI:33438837"
                     /db_xref="SGD:S000028678"
                     /db_xref="GeneID:1466413"
                     /translation="MIVDFYSNTLRHCETLRSQPCSLFSSLYARSFQSSCTLHVAEPS
                     PGFHMYGCHT"
     gene            482045..482163
                     /locus_tag="RDN5-4"
                     /db_xref="GeneID:9164929"
     rRNA            482045..482163
                     /locus_tag="RDN5-4"
                     /product="RDN5-4"
                     /note="Variant 5S ribosomal rRNA (5S rRNA) gene; located
                     at a site distal to the RDN1 locus; unable to support cell
                     viability when provided as sole source of 5S rRNA;
                     identical in sequence to variant alleles RDN5-2, RDN5-3,
                     and RDN5-5"
                     /db_xref="SGD:S000029708"
                     /db_xref="GeneID:9164929"
     gene            complement(<482059..>482190)
                     /locus_tag="YLR157C-C"
                     /db_xref="GeneID:1466414"
     mRNA            complement(<482059..>482190)
                     /locus_tag="YLR157C-C"
                     /product="hypothetical protein"
                     /transcript_id="NM_001184561.1"
                     /db_xref="GI:296146688"
                     /db_xref="GeneID:1466414"
     CDS             complement(482059..482190)
                     /locus_tag="YLR157C-C"
                     /note="hypothetical protein; identified by fungal homology
                     comparisons and RT-PCR; this ORF partially overlaps
                     RDN5-4; YLR157C-C has a paralog, YLR154C-H, that arose
                     from a segmental duplication"
                     /codon_start=1
                     /product="hypothetical protein"
                     /protein_id="NP_878122.1"
                     /db_xref="GI:33438834"
                     /db_xref="SGD:S000028565"
                     /db_xref="GeneID:1466414"
                     /translation="MYSCAKKKTTAAPEFRVWSPTTLLGQALTSLTTVDRTGNGAFW"
     gene            complement(<482549..>483637)
                     /gene="ASP3-3"
                     /locus_tag="YLR158C"
                     /gene_synonym="ASP3"
                     /db_xref="GeneID:850855"
     mRNA            complement(<482549..>483637)
                     /gene="ASP3-3"
                     /locus_tag="YLR158C"
                     /gene_synonym="ASP3"
                     /product="asparaginase ASP3-3"
                     /transcript_id="NM_001182045.1"
                     /db_xref="GI:296146698"
                     /db_xref="GeneID:850855"
     CDS             complement(482549..483637)
                     /gene="ASP3-3"
                     /locus_tag="YLR158C"
                     /gene_synonym="ASP3"
                     /EC_number="3.5.1.1"
                     /note="Cell-wall L-asparaginase II involved in asparagine
                     catabolism; expression induced during nitrogen starvation;
                     ORF contains a short non-coding RNA that enhances
                     expression of full-length gene; likely arose in via
                     horizontal gene transfer from the wine yeast
                     Wickerhamomyces anomalus or a close relative; reference
                     strain S288C has four copies of ASP3; ASP3-3 has a
                     paralog, ASP3-1, that arose from a segmental duplication"
                     /codon_start=1
                     /product="asparaginase ASP3-3"
                     /protein_id="NP_013259.1"
                     /db_xref="GI:6323187"
                     /db_xref="SGD:S000004148"
                     /db_xref="GeneID:850855"
                     /translation="MRSLNTLLLSLFVAMSSGAPLLKIREEKNSSLPSIKIFGTGGTI
                     ASKGSTSATTAGYSVGLTVNDLIEAVPSLAEKANLDYLQVSNVGSNSLNYTHLIPLYH
                     GISEALASDDYAGAVVTHGTDTMEETAFFLDLTINSEKPVCIAGAMRPATATSADGPM
                     NLYQAVSIAASEKSLGRGTMITLNDRIASGFWTTKMNANSLDTFRADEQGYLGYFSND
                     DVEFYYPPVKPNGWQFFDISNLTDPSEIPEVIILYSYQGLNPELIVKAVKDLGAKGIV
                     LAGSGAGSWTATGSIVNEQLYEEYGIPIVHSRRTADGTVPPDDAPEYAIGSGYLNPQK
                     SRILLQLCLYSGYGMDQIRSVFSGVYGG"
     gene            <485345..>485689
                     /locus_tag="YLR159W"
                     /db_xref="GeneID:850856"
     mRNA            <485345..>485689
                     /locus_tag="YLR159W"
                     /product="hypothetical protein"
                     /transcript_id="NM_001182046.1"
                     /db_xref="GI:296146699"
                     /db_xref="GeneID:850856"
     CDS             485345..485689
                     /locus_tag="YLR159W"
                     /note="hypothetical protein; YLR156W, YLR159W, and YLR161W
                     are three identical open reading frames in S288C encoded
                     near the ribosomal DNA region of chromosome 12; YLR159W
                     has a paralog, YLR156W, that arose from a segmental
                     duplication"
                     /codon_start=1
                     /product="hypothetical protein"
                     /protein_id="NP_757338.1"
                     /db_xref="GI:26225100"
                     /db_xref="SGD:S000004149"
                     /db_xref="GeneID:850856"
                     /translation="MKFQYALAKEQLGSNSRSGVKKLISKHHWLPEYYFSDLSFSVVQ
                     QWDSRAIEKTTIISCMRPANQEIYPLRHCETLRSQPCSLFSSLYARSFQSSCTLHVAE
                     PSPGFHMYGCHT"
     gene            485697..485815
                     /locus_tag="RDN5-5"
                     /db_xref="GeneID:9164946"
     rRNA            485697..485815
                     /locus_tag="RDN5-5"
                     /product="RDN5-5"
                     /note="Variant 5S ribosomal rRNA (5S rRNA) gene; located
                     at a site distal to the RDN1 locus; unable to support cell
                     viability when provided as sole source of 5S rRNA;
                     identical in sequence to variant alleles RDN5-2, RDN5-3,
                     and RDN5-4"
                     /db_xref="SGD:S000029710"
                     /db_xref="GeneID:9164946"
     gene            complement(<485711..>485842)
                     /locus_tag="YLR159C-A"
                     /db_xref="GeneID:1466415"
     mRNA            complement(<485711..>485842)
                     /locus_tag="YLR159C-A"
                     /product="hypothetical protein"
                     /transcript_id="NM_001184565.1"
                     /db_xref="GI:296146700"
                     /db_xref="GeneID:1466415"
     CDS             complement(485711..485842)
                     /locus_tag="YLR159C-A"
                     /note="hypothetical protein; identified by fungal homology
                     comparisons and RT-PCR; partially overlaps RND5-5;
                     YLR159C-A has a paralog, YLR156C-A, that arose from a
                     segmental duplication"
                     /codon_start=1
                     /product="hypothetical protein"
                     /protein_id="NP_878127.1"
                     /db_xref="GI:33438839"
                     /db_xref="SGD:S000028566"
                     /db_xref="GeneID:1466415"
                     /translation="MYSCAKKKTTAAPEFRVWSPTTLLGQALTSLTTVDRTGNGAFW"
     gene            complement(<486201..>487289)
                     /gene="ASP3-4"
                     /locus_tag="YLR160C"
                     /gene_synonym="ASP3"
                     /db_xref="GeneID:850857"
     mRNA            complement(<486201..>487289)
                     /gene="ASP3-4"
                     /locus_tag="YLR160C"
                     /gene_synonym="ASP3"
                     /product="asparaginase ASP3-4"
                     /transcript_id="NM_001182047.1"
                     /db_xref="GI:296146701"
                     /db_xref="GeneID:850857"
     CDS             complement(486201..487289)
                     /gene="ASP3-4"
                     /locus_tag="YLR160C"
                     /gene_synonym="ASP3"
                     /EC_number="3.5.1.1"
                     /note="Cell-wall L-asparaginase II involved in asparagine
                     catabolism; expression induced during nitrogen starvation;
                     ORF contains a short non-coding RNA that enhances
                     expression of full-length gene; likely arose in via
                     horizontal gene transfer from the wine yeast
                     Wickerhamomyces anomalus or a close relative; reference
                     strain S288C has four copies of ASP3; ASP3-4 has a
                     paralog, ASP3-2, that arose from a segmental duplication"
                     /codon_start=1
                     /product="asparaginase ASP3-4"
                     /protein_id="NP_013261.1"
                     /db_xref="GI:6323189"
                     /db_xref="SGD:S000004150"
                     /db_xref="GeneID:850857"
                     /translation="MRSLNTLLLSLFVAMSSGAPLLKIREEKNSSLPSIKIFGTGGTI
                     ASKGSTSATTAGYSVGLTVNDLIEAVPSLAEKANLDYLQVSNVGSNSLNYTHLIPLYH
                     GISEALASDDYAGAVVTHGTDTMEETAFFLDLTINSEKPVCIAGAMRPATATSADGPM
                     NLYQAVSIAASEKSLGRGTMITLNDRIASGFWTTKMNANSLDTFRADEQGYLGYFSND
                     DVEFYYPPVKPNGWQFFDISNLTDPSEIPEVIILYSYQGLNPELIVKAVKDLGAKGIV
                     LAGSGAGSWTATGSIVNEQLYEEYGIPIVHSRRTADGTVPPDDAPEYAIGSGYLNPQK
                     SRILLQLCLYSGYGMDQIRSVFSGVYGG"
     gene            <488997..>489341
                     /locus_tag="YLR161W"
                     /db_xref="GeneID:850858"
     mRNA            <488997..>489341
                     /locus_tag="YLR161W"
                     /product="hypothetical protein"
                     /transcript_id="NM_001182048.1"
                     /db_xref="GI:296146702"
                     /db_xref="GeneID:850858"
     CDS             488997..489341
                     /locus_tag="YLR161W"
                     /note="hypothetical protein; YLR156W, YLR159W, and YLR161W
                     are three identical open reading frames in S288C encoded
                     near the ribosomal DNA region of chromosome 12; YLR161W
                     has a paralog, YLR157W-D, that arose from a segmental
                     duplication"
                     /codon_start=1
                     /product="hypothetical protein"
                     /protein_id="NP_757339.1"
                     /db_xref="GI:26225101"
                     /db_xref="SGD:S000004151"
                     /db_xref="GeneID:850858"
                     /translation="MKFQYALAKEQLGSNSRSGVKKLISKHHWLPEYYFSDLSFSVVQ
                     QWDSRAIEKTTIISCMRPANQEIYPLRHCETLRSQPCSLFSSLYARSFQSSCTLHVAE
                     PSPGFHMYGCHT"
     gene            489349..489469
                     /locus_tag="RDN5-6"
                     /db_xref="GeneID:9164918"
     rRNA            489349..489469
                     /locus_tag="RDN5-6"
                     /product="RDN5-6"
                     /note="Variant 5S ribosomal rRNA (5S rRNA) gene; located
                     at a site distal to the RDN1 locus"
                     /db_xref="SGD:S000029711"
                     /db_xref="GeneID:9164918"
     gene            <489573..>489929
                     /locus_tag="YLR162W"
                     /db_xref="GeneID:850859"
     mRNA            <489573..>489929
                     /locus_tag="YLR162W"
                     /product="hypothetical protein"
                     /transcript_id="NM_001182049.1"
                     /db_xref="GI:296146703"
                     /db_xref="GeneID:850859"
     CDS             489573..489929
                     /locus_tag="YLR162W"
                     /note="hypothetical protein; overexpression confers
                     resistance to the antimicrobial peptide MiAMP1 and causes
                     growth arrest, apoptosis, and increased sensitivity to
                     cobalt chloride"
                     /codon_start=1
                     /product="hypothetical protein"
                     /protein_id="NP_013263.1"
                     /db_xref="GI:6323191"
                     /db_xref="SGD:S000004152"
                     /db_xref="GeneID:850859"
                     /translation="MQHTLTRTASLPERSSSAHSAATALPALRRPPDSCETLVPLLCI
                     FWFVFVSMSPLPPARANKSDNKGLISADRNNKATLLLTIPRCTSKSYTNDLSPLKMTL
                     LSAGKHPRPFRQEHRC"
     gene            <490406..>490594
                     /gene="RRT15"
                     /locus_tag="YLR162W-A"
                     /db_xref="GeneID:1466416"
     mRNA            <490406..>490594
                     /gene="RRT15"
                     /locus_tag="YLR162W-A"
                     /product="Rrt15p"
                     /transcript_id="NM_001184566.1"
                     /db_xref="GI:296146704"
                     /db_xref="GeneID:1466416"
     CDS             490406..490594
                     /gene="RRT15"
                     /locus_tag="YLR162W-A"
                     /note="hypothetical protein; identified by fungal homology
                     comparisons and RT-PCR; identified in a screen for mutants
                     with decreased levels of rDNA transcription"
                     /codon_start=1
                     /product="Rrt15p"
                     /protein_id="NP_878128.1"
                     /db_xref="GI:33438840"
                     /db_xref="SGD:S000028567"
                     /db_xref="GeneID:1466416"
                     /translation="MVCIHTENQNQGDFYPFVLLEISVLHESPLGHLRYRLTDVPPQP
                     NSPGEIYCFYINCIMNRR"
     gene            complement(<491866..>493254)
                     /gene="MAS1"
                     /locus_tag="YLR163C"
                     /gene_synonym="MIF1"
                     /db_xref="GeneID:850860"
     mRNA            complement(<491866..>493254)
                     /gene="MAS1"
                     /locus_tag="YLR163C"
                     /gene_synonym="MIF1"
                     /product="Mas1p"
                     /transcript_id="NM_001182050.1"
                     /db_xref="GI:296146705"
                     /db_xref="GeneID:850860"
     CDS             complement(491866..493254)
                     /gene="MAS1"
                     /locus_tag="YLR163C"
                     /gene_synonym="MIF1"
                     /EC_number="3.4.24.64"
                     /note="Smaller subunit of the mitochondrial processing
                     protease (MPP); essential processing enzyme that cleaves
                     the N-terminal targeting sequences from mitochondrially
                     imported proteins"
                     /codon_start=1
                     /product="Mas1p"
                     /protein_id="NP_013264.1"
                     /db_xref="GI:6323192"
                     /db_xref="SGD:S000004153"
                     /db_xref="GeneID:850860"
                     /translation="MFSRTASKFRNTRRLLSTISSQIPGTRTSKLPNGLTIATEYIPN
                     TSSATVGIFVDAGSRAENVKNNGTAHFLEHLAFKGTQNRSQQGIELEIENIGSHLNAY
                     TSRENTVYYAKSLQEDIPKAVDILSDILTKSVLDNSAIERERDVIIRESEEVDKMYDE
                     VVFDHLHEITYKDQPLGRTILGPIKNIKSITRTDLKDYITKNYKGDRMVLAGAGAVDH
                     EKLVQYAQKYFGHVPKSESPVPLGSPRGPLPVFCRGERFIKENTLPTTHIAIALEGVS
                     WSAPDYFVALATQAIVGNWDRAIGTGTNSPSPLAVAASQNGSLANSYMSFSTSYADSG
                     LWGMYIVTDSNEHNVQLIVNEILKEWKRIKSGKISDAEVNRAKAQLKAALLLSLDGST
                     AIVEDIGRQVVTTGKRLSPEEVFEQVDKITKDDIIMWANYRLQNKPVSMVALGNTSTV
                     PNVSYIEEKLNQ"
     gene            <493883..>494389
                     /gene="SHH4"
                     /locus_tag="YLR164W"
                     /db_xref="GeneID:850861"
     mRNA            <493883..>494389
                     /gene="SHH4"
                     /locus_tag="YLR164W"
                     /product="protein SHH4"
                     /transcript_id="NM_001182051.1"
                     /db_xref="GI:296146706"
                     /db_xref="GeneID:850861"
     CDS             493883..494389
                     /gene="SHH4"
                     /locus_tag="YLR164W"
                     /note="Mitochondrial inner membrane hypothetical protein;
                     similar to Tim18p; a fraction copurifies with Sdh3p, but
                     Shh4p is neither a stoichiometric subunit of succinate
                     dehydrogenase nor of the TIM22 translocase; expression
                     induced by nitrogen limitation in a GLN3, GAT1-dependent
                     manner; SHH4 has a paralog, SDH4, that arose from the
                     whole genome duplication"
                     /codon_start=1
                     /product="protein SHH4"
                     /protein_id="NP_013265.1"
                     /db_xref="GI:6323193"
                     /db_xref="SGD:S000004154"
                     /db_xref="GeneID:850861"
                     /translation="MSSTKFLKPLCRIRAFHTSIARSFTIPFLPKIPQKPGGVSGTAN
                     DSSYMPPESRAQGSYHWIVERGLSLAVLPLIAVPLVTTGPISTFTDTFLSLVLLGHCH
                     IGFQSCIIDYISERVYGKVHHYAMYLLSLGSFLSFVGIYKLESQEAGLIASLKSLWDN
                     KPVEKKRQ"
     gene            complement(<494494..>495258)
                     /gene="PUS5"
                     /locus_tag="YLR165C"
                     /db_xref="GeneID:850862"
     mRNA            complement(<494494..>495258)
                     /gene="PUS5"
                     /locus_tag="YLR165C"
                     /product="pseudouridine synthase PUS5"
                     /transcript_id="NM_001182052.1"
                     /db_xref="GI:296146707"
                     /db_xref="GeneID:850862"
     CDS             complement(494494..495258)
                     /gene="PUS5"
                     /locus_tag="YLR165C"
                     /EC_number="5.4.99.43"
                     /note="Pseudouridine synthase; catalyzes only the
                     formation of pseudouridine (Psi)-2819 in mitochondrial 21S
                     rRNA; not essential for viability"
                     /codon_start=1
                     /product="pseudouridine synthase PUS5"
                     /protein_id="NP_013266.1"
                     /db_xref="GI:6323194"
                     /db_xref="SGD:S000004155"
                     /db_xref="GeneID:850862"
                     /translation="MSLKKQIPIIFENTHYFIVNKPPGIPSQPPDCRTWGRTHPNLDP
                     TPLLERFKAIYYSHREVELCRTVHRLDHCVTGGMLIAKTKDGSVKFSRFLQKGGNNGY
                     KLQRKYVAIVESSGRFNKPNNYEIKYGPKYNFLISHGGREITKFKEVDENCIVLQLVT
                     GKKHQIRNHVSQILNQPILNDKRHGSTVNFPELFNDQIALHSACIITKIGLQTKTHLI
                     PMEHNNTGQLWSRKYVNEEGEFTLPIKEVLLENWDQ"
     gene            complement(<495429..>498044)
                     /gene="SEC10"
                     /locus_tag="YLR166C"
                     /db_xref="GeneID:850863"
     mRNA            complement(<495429..>498044)
                     /gene="SEC10"
                     /locus_tag="YLR166C"
                     /product="Sec10p"
                     /transcript_id="NM_001182053.1"
                     /db_xref="GI:296146708"
                     /db_xref="GeneID:850863"
     CDS             complement(495429..498044)
                     /gene="SEC10"
                     /locus_tag="YLR166C"
                     /note="Essential 100kDa subunit of the exocyst complex;
                     the exocyst mediates polarized targeting and tethering of
                     post-Golgi secretory vesicles to active sites of
                     exocytosis at the plasma membrane prior to SNARE-mediated
                     fusion"
                     /codon_start=1
                     /product="Sec10p"
                     /protein_id="NP_013267.1"
                     /db_xref="GI:6323195"
                     /db_xref="SGD:S000004156"
                     /db_xref="GeneID:850863"
                     /translation="MNSLYELDPKWKKLLKTDNFLGGLTVNEFVQELSKDHRNDVLID
                     ANTKNLPTNEKDQDAIREAIWKQLDPKPYIRTFESTLKELKNLNEETLNKRQYFSEQV
                     ATQEVIHSENVIKLSKDLHTTLLTFDKLDDRLTNVTQVVSPLGDKLETAIKKKQNYIQ
                     SVELIRRYNDFYSMGKSDIVEQLRLSKNWKLNLKSVKLMKNLLILSSKLETSSIPKTI
                     NTKLVIEKYSEMMENELLENFNSAYRENNFTKLNEIAIILNNFNGGVNVIQSFINQHD
                     YFIDTKQIDLENEFENVFIKNVKFKEQLIDFENHSVIIETSMQNLINDVETVIKNESK
                     IVKRVFEEKATHVIQLFIQRVFAQKIEPRFEVLLRNSLSISNLAYVRILHGLFTLFGK
                     FTKSLIDYFQLLEIDDSNQILSTTLEQCFADLFSHYLYDRSKYFGIEKRSLEAILVDM
                     TSKFTVNYDKEINKRVLLDKYKEKLSTNVDAFMHSPRGNTHSRQDSTSRSKLSQFNSF
                     LKTHLDKDHLSLNRTNTLSDSFNNSSSSTQYDVANNSSSLVNSSFTASDIDNSPNSPA
                     NYSLNDVDSMLKCVVESTARVMELIPNKAHLYILEILKIMFLGIVDSYMEIALEVAYW
                     KICKVDINKTAGVVNLNFLKFISMSTEILDLLSISIKSIFLPLLNNSPEIKAQIIEMT
                     NSQIQKMEILINIILQETITVISTKFSAILCKQKKKDFVPKSQELLDQDTLPAIEIVN
                     ILNLIFEQSSKFLKGKNLQTFLTLIGEELYGLLLSHYSHFQVNSIGGVVVTKDIIGYQ
                     TAIEDWGVASLIDKFATLRELANLFTVQPELLESLTKEGHLADIGRDIIQSYISNRED
                     FNHDNFINSVKLNFR"
     gene            <498947..>499405
                     /gene="RPS31"
                     /locus_tag="YLR167W"
                     /gene_synonym="RPS37; UBI3"
                     /db_xref="GeneID:850864"
     mRNA            <498947..>499405
                     /gene="RPS31"
                     /locus_tag="YLR167W"
                     /gene_synonym="RPS37; UBI3"
                     /product="ubiquitin-ribosomal 40S subunit protein S31
                     fusion protein"
                     /transcript_id="NM_001182054.1"
                     /db_xref="GI:296146709"
                     /db_xref="GeneID:850864"
     CDS             498947..499405
                     /gene="RPS31"
                     /locus_tag="YLR167W"
                     /gene_synonym="RPS37; UBI3"
                     /note="Fusion protein cleaved to yield ribosomal protein
                     S31 and ubiquitin; ubiquitin may facilitate assembly of
                     the ribosomal protein into ribosomes; interacts
                     genetically with translation factor eIF2B; homologous to
                     mammalian ribosomal protein S27A, no bacterial homolog"
                     /codon_start=1
                     /product="ubiquitin-ribosomal 40S subunit protein S31
                     fusion protein"
                     /protein_id="NP_013268.1"
                     /db_xref="GI:6323196"
                     /db_xref="SGD:S000004157"
                     /db_xref="GeneID:850864"
                     /translation="MQIFVKTLTGKTITLEVESSDTIDNVKSKIQDKEGIPPDQQRLI
                     FAGKQLEDGRTLSDYNIQKESTLHLVLRLRGGGKKRKKKVYTTPKKIKHKHKKVKLAV
                     LSYYKVDAEGKVTKLRRECSNPTCGAGVFLANHKDRLYCGKCHSVYKVNA"
     gene            complement(<499578..>500270)
                     /gene="UPS2"
                     /locus_tag="YLR168C"
                     /gene_synonym="AIM30; GEP1; MSF1; MSF1'"
                     /db_xref="GeneID:850865"
     mRNA            complement(<499578..>500270)
                     /gene="UPS2"
                     /locus_tag="YLR168C"
                     /gene_synonym="AIM30; GEP1; MSF1; MSF1'"
                     /product="Ups2p"
                     /transcript_id="NM_001182055.1"
                     /db_xref="GI:296146710"
                     /db_xref="GeneID:850865"
     CDS             complement(499578..500270)
                     /gene="UPS2"
                     /locus_tag="YLR168C"
                     /gene_synonym="AIM30; GEP1; MSF1; MSF1'"
                     /note="Mitochondrial intermembrane space protein; involved
                     in phospholipid metabolism; has role in regulation of
                     phospholipid metabolism by inhibiting conversion of
                     phosphatidylethanolamine to phosphatidylcholine; null
                     mutant has defects in mitochondrial morphology; similar to
                     Ups1p, Ups3p and to human PRELI; UPS2 has a paralog, UPS3,
                     that arose from the whole genome duplication"
                     /codon_start=1
                     /product="Ups2p"
                     /protein_id="NP_013269.1"
                     /db_xref="GI:6323197"
                     /db_xref="SGD:S000004158"
                     /db_xref="GeneID:850865"
                     /translation="MKLFQNSYDFNYPWDQVTAANWKKYPNEISTHVIAVDVLRRELK
                     DQGKVLVTERLITVKQGVPKWIMMMLGGTNMSHVREVSVVDLNKKSLTMRSCNLTMCN
                     LLKVYETVTYSPHPDDSANKTLFQQEAQITAYGSIRKLCNKMEDWSVQRFCENAKKGK
                     MGFDAVLQVFSENWEKHVDDLSNQLVSKVNETMEDVKISAGTLLKGTERSGRTILQQN
                     IDLFRDAYNHEN"
     gene            complement(<500579..>501049)
                     /gene="APS1"
                     /locus_tag="YLR170C"
                     /gene_synonym="YAP19"
                     /db_xref="GeneID:850868"
     mRNA            complement(<500579..>501049)
                     /gene="APS1"
                     /locus_tag="YLR170C"
                     /gene_synonym="YAP19"
                     /product="Aps1p"
                     /transcript_id="NM_001182057.1"
                     /db_xref="GI:296146711"
                     /db_xref="GeneID:850868"
     CDS             complement(500579..501049)
                     /gene="APS1"
                     /locus_tag="YLR170C"
                     /gene_synonym="YAP19"
                     /note="Small subunit of the clathrin-associated adaptor
                     complex AP-1; AP-1 is involved in protein sorting at the
                     trans-Golgi network; homolog of the sigma subunit of the
                     mammalian clathrin AP-1 complex"
                     /codon_start=1
                     /product="Aps1p"
                     /protein_id="NP_013271.1"
                     /db_xref="GI:6323200"
                     /db_xref="SGD:S000004160"
                     /db_xref="GeneID:850868"
                     /translation="MTQLKYLLLVSRQGKIRLKKWYTAMSAGEKAKIVKDLTPTILAR
                     KPKMCNIIEYNDHKVVYKRYASLYFIVGMTPDVDNELLTLEIIHRFVETMDTYFGNVC
                     ELDIIFNFSKVYDILNEMIMCDGSIAESSRKEVLHHVTVMDTMESNDNLERVLS"
     gene            complement(<501260..>502162)
                     /gene="DPH5"
                     /locus_tag="YLR172C"
                     /db_xref="GeneID:850869"
     mRNA            complement(<501260..>502162)
                     /gene="DPH5"
                     /locus_tag="YLR172C"
                     /product="diphthine synthase"
                     /transcript_id="NM_001182059.1"
                     /db_xref="GI:296146712"
                     /db_xref="GeneID:850869"
     CDS             complement(501260..502162)
                     /gene="DPH5"
                     /locus_tag="YLR172C"
                     /EC_number="2.1.1.98"
                     /note="Methyltransferase required for synthesis of
                     diphthamide; diphthamide is a modified histidine residue
                     of translation elongation factor 2 (Eft1p or Eft2p); not
                     essential for viability; GFP-Dph5p fusion protein
                     localizes to the cytoplasm"
                     /codon_start=1
                     /product="diphthine synthase"
                     /protein_id="NP_013273.1"
                     /db_xref="GI:6323201"
                     /db_xref="SGD:S000004162"
                     /db_xref="GeneID:850869"
                     /translation="MLYLIGLGLSYKSDITVRGLEAIKKCSRVYLEHYTSILMAASQE
                     ELESYYGKEIILADRELVETGSKQILNNADKEDVAFLVVGDPFGATTHTDLVLRAKRE
                     AIPVEIIHNASVMNAVGACGLQLYNFGQTVSMVFFTDNWRPDSWYDKIWENRKIGLHT
                     LVLLDIKVKEQSIENMARGRLIYEPPRYMSIAQCCEQLLEIEEKRGTKAYTPDTPAVA
                     ISRLGSSSQSFKSGTISELANYDSGEPLHSLVILGRQCHELELEYLLEFADDKEKFGK
                     DVANDQEYFKPAAWVPPTEDDSDE"
     gene            <502421..>504247
                     /locus_tag="YLR173W"
                     /db_xref="GeneID:850870"
     mRNA            <502421..>504247
                     /locus_tag="YLR173W"
                     /product="hypothetical protein"
                     /transcript_id="NM_001182060.1"
                     /db_xref="GI:296146713"
                     /db_xref="GeneID:850870"
     CDS             502421..504247
                     /locus_tag="YLR173W"
                     /codon_start=1
                     /product="hypothetical protein"
                     /protein_id="NP_013274.1"
                     /db_xref="GI:6323202"
                     /db_xref="SGD:S000004163"
                     /db_xref="GeneID:850870"
                     /translation="MHTNSPLRADNQDLETQPLLRPNTEESQLLNDEVRINVANETLI
                     KSRWRSIKCLIIYLLGIVLLSFFGVSIVQYIRGHVPPTDVIEKNLVQVTNFKLVEFQL
                     DGWKDNMGSDLNNDTGKYLQVSIHSQIWFDYDKWPGTENDSDARSQRDWIRYINEKVL
                     KTICIDLNNVTTFDGDLVFKNKLGDVVGMEPICFNLAHRQINNLQFKILVKPSIWKIV
                     KVLKKFWNRDFESLNIKSNLDMTIFKRKFGTRFNLLKLNDEILDWKDIIDWEKISATP
                     LRMIQNMIDGISLQGFTLRDSSSDGFHADMRLNPITILGGVDWLHLPPGTSIPFINWE
                     IKLPDCNGEPAIAIPTLSCFNEPINLHHDKDNIVVCLQNEIEGPLPDELLYQECPQNS
                     LTPMSQIVNAVLNQNETVTFAARGHVLEDGIDNNSLIPADMLEDIFQEASFIPITTNA
                     TFNSSELIQEFQINDLQLRWAARKKLSLVGTFLGFFDLSFYETHQQDRVRIDTIRGQI
                     DLYHNDINFLNLPMKQWINSSSHILHDEDTGNTQMKLQFDLENDDMEVVNSLELTRTL
                     NEILFQGFTVIHFNATIDASLTTALGPWVLTGLAGEGDTLVT"
     gene            <504591..>505829
                     /gene="IDP2"
                     /locus_tag="YLR174W"
                     /db_xref="GeneID:850871"
     mRNA            <504591..>505829
                     /gene="IDP2"
                     /locus_tag="YLR174W"
                     /product="isocitrate dehydrogenase (NADP(+)) IDP2"
                     /transcript_id="NM_001182061.1"
                     /db_xref="GI:296146714"
                     /db_xref="GeneID:850871"
     CDS             504591..505829
                     /gene="IDP2"
                     /locus_tag="YLR174W"
                     /EC_number="1.1.1.42"
                     /note="Cytosolic NADP-specific isocitrate dehydrogenase;
                     catalyzes oxidation of isocitrate to alpha-ketoglutarate;
                     levels are elevated during growth on non-fermentable
                     carbon sources and reduced during growth on glucose; IDP2
                     has a paralog, IDP3, that arose from the whole genome
                     duplication"
                     /codon_start=1
                     /product="isocitrate dehydrogenase (NADP(+)) IDP2"
                     /protein_id="NP_013275.1"
                     /db_xref="GI:6323203"
                     /db_xref="SGD:S000004164"
                     /db_xref="GeneID:850871"
                     /translation="MTKIKVANPIVEMDGDEQTRIIWHLIRDKLVLPYLDVDLKYYDL
                     SVEYRDQTNDQVTVDSATATLKYGVAVKCATITPDEARVEEFHLKKMWKSPNGTIRNI
                     LGGTVFREPIIIPRIPRLVPQWEKPIIIGRHAFGDQYKATDVIVPEEGELRLVYKSKS
                     GTHDVDLKVFDYPEHGGVAMMMYNTTDSIEGFAKASFELAIERKLPLYSTTKNTILKK
                     YDGKFKDVFEAMYARSYKEKFESLGIWYEHRLIDDMVAQMLKSKGGYIIAMKNYDGDV
                     ESDIVAQGFGSLGLMTSVLITPDGKTFESEAAHGTVTRHFRQHQQGKETSTNSIASIF
                     AWTRGIIQRGKLDNTPDVVKFGQILESATVNTVQEDGIMTKDLALILGKSERSAYVTT
                     EEFIDAVESRLKKEFEAAAL"
     gene            <506134..>507585
                     /gene="CBF5"
                     /locus_tag="YLR175W"
                     /db_xref="GeneID:850872"
     mRNA            <506134..>507585
                     /gene="CBF5"
                     /locus_tag="YLR175W"
                     /product="pseudouridine synthase CBF5"
                     /transcript_id="NM_001182062.1"
                     /db_xref="GI:296146715"
                     /db_xref="GeneID:850872"
     CDS             506134..507585
                     /gene="CBF5"
                     /locus_tag="YLR175W"
                     /EC_number="5.4.99.-"
                     /note="Pseudouridine synthase catalytic subunit of box
                     H/ACA snoRNPs; acts on both large and small rRNAs and on
                     snRNA U2; mutations in human ortholog dyskerin cause the
                     disorder dyskeratosis congenita; small nucleolar
                     ribonucleoprotein particles are also known as snoRNPs"
                     /codon_start=1
                     /product="pseudouridine synthase CBF5"
                     /protein_id="NP_013276.1"
                     /db_xref="GI:6323204"
                     /db_xref="SGD:S000004165"
                     /db_xref="GeneID:850872"
                     /translation="MSKEDFVIKPEAAGASTDTSEWPLLLKNFDKLLVRSGHYTPIPA
                     GSSPLKRDLKSYISSGVINLDKPSNPSSHEVVAWIKRILRCEKTGHSGTLDPKVTGCL
                     IVCIDRATRLVKSQQGAGKEYVCIVRLHDALKDEKDLGRSLENLTGALFQRPPLISAV
                     KRQLRVRTIYESNLIEFDNKRNLGVFWASCEAGTYMRTLCVHLGMLLGVGGHMQELRR
                     VRSGALSENDNMVTLHDVMDAQWVYDNTRDESYLRSIIQPLETLLVGYKRIVVKDSAV
                     NAVCYGAKLMIPGLLRYEEGIELYDEIVLITTKGEAIAVAIAQMSTVDLASCDHGVVA
                     SVKRCIMERDLYPRRWGLGPVAQKKKQMKADGKLDKYGRVNENTPEQWKKEYVPLDNA
                     EQSTSSSQETKETEEEPKKAKEDSLIKEVETEKEEVKEDDSKKEKKEKKDKKEKKEKK
                     EKKDKKEKKEKKEKKRKSEDGDSEEKKSKKSKK"
     gene            complement(<507797..>510232)
                     /gene="RFX1"
                     /locus_tag="YLR176C"
                     /gene_synonym="CRT1"
                     /db_xref="GeneID:850873"
     mRNA            complement(<507797..>510232)
                     /gene="RFX1"
                     /locus_tag="YLR176C"
                     /gene_synonym="CRT1"
                     /product="Rfx1p"
                     /transcript_id="NM_001182063.1"
                     /db_xref="GI:296146716"
                     /db_xref="GeneID:850873"
     CDS             complement(507797..510232)
                     /gene="RFX1"
                     /locus_tag="YLR176C"
                     /gene_synonym="CRT1"
                     /note="Major transcriptional repressor of
                     DNA-damage-regulated genes; recruits repressors Tup1p and
                     Cyc8p to their promoters; involved in DNA damage and
                     replication checkpoint pathway; similar to a family of
                     mammalian DNA binding RFX1-4 proteins"
                     /codon_start=1
                     /product="Rfx1p"
                     /protein_id="NP_013277.1"
                     /db_xref="GI:6323205"
                     /db_xref="SGD:S000004166"
                     /db_xref="GeneID:850873"
                     /translation="MVIFKERKPTENLFTRKIPAKYFIFSPSFLSVHYFEFYLPMSGD
                     NNIEPTSRGSNDNSNGPSNGSSVNSNRYSLNAPKYSSQPPPASHTYLPPMSVNIPPIA
                     SKSSSIYSLLHQSSPRPETPNPILPPLIGSGPGSHKPSPTPTQPPAQPATQRQPATYS
                     VYPASISLNRSNSSAYPLSFKSEETLNNNPPTAAKRTNTFPSIPSSTKKQKTSQEKRI
                     SSISRRNTQEIIAKQIAENNKSKTIEEYAQIVKHAEIKVLSMDSQNTSKAALQLAEQN
                     RERERQVFALLWLMKNCKSQHDSYVPRGKIFAQYASSCSQNNLKPLSQASLGKLIRTV
                     FPDLTTRRLGMRGQSKYHYCGLKLTVNESGSVSLNNNNASLSLVHNNDPISPLSSPSP
                     SSPSPQVPNVSSPFSLNRKSLSRTGSPVKQSSNDNPNEPELESQHPNETEANKLDSLP
                     PAANNPTGTLSSDELTFTHDLIEKVFNCNDKLSDNYNTQILSNTEHPLLTSYKLDFPK
                     IPAGVLPTDTDSDVISSLESLYHIHCNSVYECIKFLKSDNISNALFFSNSNSISPTMF
                     NLFISEPLIDWVTKCDLITYTGLIKFFSQFIIHSNEISDSIIQKLESMIKLLPEQINK
                     AVLELPKALVQRKLSIINNFTKLVKKLIKLLKFILNFLKSFPIFKSGMNNDWKNIVNL
                     DDILEMMINEDDTNSETNTIMQHLQGFCQVFVTKFLNSSMSVSNDPSVSIECKSLNEM
                     IKDFCSFISLQSKFSCLKLIDCSTRFRNAIIGDISLKSNENLLSWLFLNNVMGQLLNY
                     CFEVMKFVNGLKV"
     gene            <511054..>512940
                     /locus_tag="YLR177W"
                     /db_xref="GeneID:850874"
     mRNA            <511054..>512940
                     /locus_tag="YLR177W"
                     /product="hypothetical protein"
                     /transcript_id="NM_001182064.1"
                     /db_xref="GI:296146717"
                     /db_xref="GeneID:850874"
     CDS             511054..512940
                     /locus_tag="YLR177W"
                     /note="hypothetical protein; phosphorylated by Dbf2p-Mob1p
                     in vitro; some strains contain microsatellite polymophisms
                     at this locus; not an essential gene; YLR177W has a
                     paralog, PSP1, that arose from the whole genome
                     duplication"
                     /codon_start=1
                     /product="hypothetical protein"
                     /protein_id="NP_013278.1"
                     /db_xref="GI:6323206"
                     /db_xref="SGD:S000004167"
                     /db_xref="GeneID:850874"
                     /translation="MELPSINSTTSISDNQELRNYYDKLLFKNNSGKSLADLPGKMAD
                     FNDNSAAAHPRSRVDFINGYIGFREDKQSLLGQKNTKRASFSAFADEGRKQSEMSING
                     KSPNLSLFSFEFNGTPTQDRKPYKQDYLNVMNTSPNNILSPLNNSSQKYYPQKQQQQQ
                     QQQQQQQQQSIFDPGRRSSYISDALIHGNAATQQPQYSQPVYINNNPSLQVPYTAPSE
                     YTQQQQYSSPFNARRNTQPVLNLHPAAAPTNDAGLAVVDGKNLTSSKELHDLYLDCGS
                     NYFASDKVYKFIDSIKGTLRGDNVSASSSRIIEFLDFLKNCNLNYNPQSDAFISTAVS
                     NASSTGAAKSKNSTSMHLHYKPLVLVSLKNGKLELLSKPQTATLILKRGDLVIIDGDR
                     GKDLVLVVEPVVDINLALFINFLKKKIHFDSLITNSQQHFPNDQFIKTLVDTTNGKPV
                     AHELNPKLYDIIELTQLIIPSKQVLRFATPWESSTNLHNKFQDELKALHIAQLKLRSL
                     NNNNSGGGLNIKILNAEFQFDRKKLTFYYICQERNDFRDLIKELFKFYKTRIWLCAIP
                     NNLSIDSKFYDSNKFEWEMYQDMMSHYSMDNTGIVVAPELNRLKLDDFQIGVYMELVK
                     VLFG"
     rep_origin      512867..513115
                     /note="ARS1217;
                     Autonomously Replicating Sequence"
                     /db_xref="SGD:S000118476"
     gene            complement(<513162..>513821)
                     /gene="TFS1"
                     /locus_tag="YLR178C"
                     /gene_synonym="DKA1"
                     /db_xref="GeneID:850875"
     mRNA            complement(<513162..>513821)
                     /gene="TFS1"
                     /locus_tag="YLR178C"
                     /gene_synonym="DKA1"
                     /product="Tfs1p"
                     /transcript_id="NM_001182065.1"
                     /db_xref="GI:296146718"
                     /db_xref="GeneID:850875"
     CDS             complement(513162..513821)
                     /gene="TFS1"
                     /locus_tag="YLR178C"
                     /gene_synonym="DKA1"
                     /note="Protein that interacts with and inhibits
                     carboxypeptidase Y and Ira2p;
                     phosphatidylethanolamine-binding protein (PEBP) family
                     member; targets to vacuolar membranes during stationary
                     phase; acetylated by NatB N-terminal acetyltransferase;
                     protein abundance increases in response to DNA replication
                     stress"
                     /codon_start=1
                     /product="Tfs1p"
                     /protein_id="NP_013279.1"
                     /db_xref="GI:6323207"
                     /db_xref="SGD:S000004168"
                     /db_xref="GeneID:850875"
                     /translation="MNQAIDFAQASIDSYKKHGILEDVIHDTSFQPSGILAVEYSSSA
                     PVAMGNTLPTEKARSKPQFQFTFNKQMQKSVPQANAYVPQDDDLFTLVMTDPDAPSKT
                     DHKWSEFCHLVECDLKLLNEATHETSGATEFFASEFNTKGSNTLIEYMGPAPPKGSGP
                     HRYVFLLYKQPKGVDSSKFSKIKDRPNWGYGTPATGVGKWAKENNLQLVASNFFYAET
                     K"
     gene            complement(<514108..>514713)
                     /locus_tag="YLR179C"
                     /db_xref="GeneID:850876"
     mRNA            complement(<514108..>514713)
                     /locus_tag="YLR179C"
                     /product="hypothetical protein"
                     /transcript_id="NM_001182066.1"
                     /db_xref="GI:296146719"
                     /db_xref="GeneID:850876"
     CDS             complement(514108..514713)
                     /locus_tag="YLR179C"
                     /note="hypothetical protein with similarity to Tfs1p;
                     transcription is activated by paralogous proteins Yrm1p
                     and Yrr1p along with proteins involved in multidrug
                     resistance; GFP-tagged protein localizes to the cytoplasm
                     and nucleus"
                     /codon_start=1
                     /product="hypothetical protein"
                     /protein_id="NP_013280.1"
                     /db_xref="GI:6323208"
                     /db_xref="SGD:S000004169"
                     /db_xref="GeneID:850876"
                     /translation="MSSAIVAKLNKEDIIKDTVKDLAFEILGELSVSYVDSDDIKLGN
                     PMPMEATQAAPTIKFTPFDKSQLSAEDKLALLMTDPDAPSRTEHKWSEVCHYIITDIP
                     VEYGPGGDIAISGKGVVRNNYIGPGPPKNSGYHRYVFFLCKQPKGADSSTFTKVENII
                     SWGYGTPGAGAYDYIKENNLQLVGANYYMVENTTVDFNYDM"
     gene            <515262..>516410
                     /gene="SAM1"
                     /locus_tag="YLR180W"
                     /gene_synonym="ETH10"
                     /db_xref="GeneID:850877"
     mRNA            <515262..>516410
                     /gene="SAM1"
                     /locus_tag="YLR180W"
                     /gene_synonym="ETH10"
                     /product="methionine adenosyltransferase SAM1"
                     /transcript_id="NM_001182067.1"
                     /db_xref="GI:296146720"
                     /db_xref="GeneID:850877"
     CDS             515262..516410
                     /gene="SAM1"
                     /locus_tag="YLR180W"
                     /gene_synonym="ETH10"
                     /EC_number="2.5.1.6"
                     /note="S-adenosylmethionine synthetase; catalyzes transfer
                     of the adenosyl group of ATP to the sulfur atom of
                     methionine; SAM1 has a paralog, SAM2, that arose from the
                     whole genome duplication"
                     /codon_start=1
                     /product="methionine adenosyltransferase SAM1"
                     /protein_id="NP_013281.1"
                     /db_xref="GI:6323209"
                     /db_xref="SGD:S000004170"
                     /db_xref="GeneID:850877"
                     /translation="MAGTFLFTSESVGEGHPDKICDQVSDAILDACLAEDPHSKVACE
                     TAAKTGMIMVFGEITTKAQLDYQKIVRDTIKKIGYDDSAKGFDYKTCNVLVAIEQQSP
                     DIAQGVHEEKDLEDIGAGDQGIMFGYATDETPEGLPLTILLAHKLNMAMADARRDGSL
                     AWLRPDTKTQVTVEYKDDHGRWVPQRIDTVVVSAQHADEITTEDLRAQLKSEIIEKVI
                     PRDMLDENTKYFIQPSGRFVIGGPQGDAGLTGRKIIVDAYGGASSVGGGAFSGKDYSK
                     VDRSAAYAARWVAKSLVAAGLCKRVQVQFSYAIGIAEPLSLHVDTYGTATKSDEEIID
                     IISKNFDLRPGVLVKELDLARPIYLPTASYGHFTNQEYPWEKPKTLKF"
     gene            complement(<516678..>517670)
                     /gene="VTA1"
                     /locus_tag="YLR181C"
                     /db_xref="GeneID:850878"
     mRNA            complement(<516678..>517670)
                     /gene="VTA1"
                     /locus_tag="YLR181C"
                     /product="Vta1p"
                     /transcript_id="NM_001182068.1"
                     /db_xref="GI:296146721"
                     /db_xref="GeneID:850878"
     CDS             complement(516678..517670)
                     /gene="VTA1"
                     /locus_tag="YLR181C"
                     /note="Multivesicular body (MVB) protein; involved in
                     endosomal protein sorting; regulates Vps4p activity by
                     promoting its oligomerization; has an N-terminal Vps60-
                     and Did2- binding domain, a linker region, and a
                     C-terminal Vps4p binding domain"
                     /codon_start=1
                     /product="Vta1p"
                     /protein_id="NP_013282.1"
                     /db_xref="GI:6323210"
                     /db_xref="SGD:S000004171"
                     /db_xref="GeneID:850878"
                     /translation="MASNAARVVATAKDFDKVGLGIIGYYLQLYAVELILSEEDRSQE
                     MTALATELLDTIEAFKKEIGGESEAEDSDKSLHVMNTLIHDQEKAKIYMLNFTMSLYN
                     EKLKQLKDGPWDVMLKRSLWCCIDLFSCILHLWKENISETSTNSLQKRIKYCKIYLSK
                     LAKGEIGSSDEKTLDYADFADDSEEIKDEDVDHQTSDLENNNNDKVEGLAPKDQTTSY
                     EPVDEVPEFIDDADSVNEEEQTVDKNEDAITKDEQQVVKKEVDLTRPSAPSEPAAAEH
                     KSYTKDELTKIMDRASKIEQIQKLAKYAISALNYEDLPTAKDELTKALDLLNSI"
     gene            <517940..>520351
                     /gene="SWI6"
                     /locus_tag="YLR182W"
                     /gene_synonym="PSL8; SDS11"
                     /db_xref="GeneID:850879"
     mRNA            <517940..>520351
                     /gene="SWI6"
                     /locus_tag="YLR182W"
                     /gene_synonym="PSL8; SDS11"
                     /product="Swi6p"
                     /transcript_id="NM_001182069.1"
                     /db_xref="GI:296146722"
                     /db_xref="GeneID:850879"
     CDS             517940..520351
                     /gene="SWI6"
                     /locus_tag="YLR182W"
                     /gene_synonym="PSL8; SDS11"
                     /note="Transcription cofactor; forms complexes with Swi4p
                     and Mbp1p to regulate transcription at the G1/S
                     transition; involved in meiotic gene expression; also
                     binds Stb1p to regulate transcription at START; cell wall
                     stress induces phosphorylation by Mpk1p, which regulates
                     Swi6p localization; required for the unfolded protein
                     response, independently of its known transcriptional
                     coactivators"
                     /codon_start=1
                     /product="Swi6p"
                     /protein_id="NP_013283.1"
                     /db_xref="GI:6323211"
                     /db_xref="SGD:S000004172"
                     /db_xref="GeneID:850879"
                     /translation="MALEEVVRYLGPHNEIPLTLTRDSETGHFLLKHFLPILQQYHDT
                     GNINETNPDSFPTDEERNKLLAHYGIAVNTDDRGELWIELEKCLQLLNMLNLFGLFQD
                     AFEFEEPETDQDEEDPSHSKLPENKTKSENSKDNISSKRINNLQDMSLDSDAHRELGS
                     PLKKLKIDTSVIDAESDSTPNTARGKPNDDINKGPSGDNENNGTDDNDRTAGPIITFT
                     HDLTSDFLSSPLKIMKALPSPVVNDNEQKMKLEAFLQRLLFPEIQEMPTSLNNDSSNR
                     NSEGGSSNQQQQHVSFDSLLQEVNDAFPNTQLNLNIPVDEHGNTPLHWLTSIANLELV
                     KHLVKHGSNRLYGDNMGESCLVKAVKSVNNYDSGTFEALLDYLYPCLILEDSMNRTIL
                     HHIIITSGMTGCSAAAKYYLDILMGWIVKKQNRPIQSGTNEKESKPNDKNGERKDSIL
                     ENLDLKWIIANMLNAQDSNGDTCLNIAARLGNISIVDALLDYGADPFIANKSGLRPVD
                     FGAGTSKLQNTNGGDENSKMVSKGDYDGQKNGKAKKIRSQLLKNPPETTSLINDVQNL
                     LNSISKDYENETVQYNEKLEKLHKELNEQREELANSREQLANVKQLKDEYSLMQEQLT
                     NLKAGIEEEEESFREESKKLGIIADESSGIDWDSSEYDADEPFKVEFLSDFLEDKLQK
                     NYEGDISKLLEAESKEQIMEQIRNQLPAEKIQSMLPPTVLLKARINAYKRNDKHLTNV
                     LDTISTKQSELENKFRRVLSLCLKIDENKVDNMLDGLLQAISSEDPQDIDTDEMQDFL
                     KKHAS"
     gene            complement(<520543..>522012)
                     /gene="TOS4"
                     /locus_tag="YLR183C"
                     /db_xref="GeneID:850880"
     mRNA            complement(<520543..>522012)
                     /gene="TOS4"
                     /locus_tag="YLR183C"
                     /product="Tos4p"
                     /transcript_id="NM_001182070.1"
                     /db_xref="GI:296146723"
                     /db_xref="GeneID:850880"
     CDS             complement(520543..522012)
                     /gene="TOS4"
                     /locus_tag="YLR183C"
                     /note="Putative transcription factor, contains Forkhead
                     Associated domain; found associated with chromatin; target
                     of SBF transcription factor; expression is periodic and
                     peaks in G1; involved in DNA replication checkpoint
                     response; interacts with Rpd3 and Set3 histone deacetylase
                     (HDAC) complexes; APCC(Cdh1) substrate; relative
                     distribution to the nucleus increases upon DNA replication
                     stress; TOS4 has a paralog, PLM2, that arose from the
                     whole genome duplication"
                     /codon_start=1
                     /product="Tos4p"
                     /protein_id="NP_013284.1"
                     /db_xref="GI:6323212"
                     /db_xref="SGD:S000004173"
                     /db_xref="GeneID:850880"
                     /translation="MSSQFPSSPYRTVDPYSPPNYKQQPNCPSSNYEKAGKTASESIG
                     NFGKGDYPTPFPSSSIGRVSSPVRSNKVDAIPSSPAFPGQLAETSPKFSSKLSSPSRH
                     TRVINAELDPSKISTITVGRNSSQCDVALCKNKFISRVHASITYLPQTNEVKIHCFSM
                     NGLIVTYRKQFDCYQLKDTMNNNNRAYRLVPRFSNEKCVKEIQDEGGFINFTLEEGDT
                     VYMTYYKGIMLDFRQVLLRISLKEKNSSSEPLRFEKKAEFESESETKHMGSIRKHPLI
                     FTDTSMDRPKKILKDSNKISIGSDSGVAERMLNHFLNSKSSPLSSVSSVDHEEQTLRQ
                     DSLSSDKNPMTMKKPKLNKRVLPSKPKKSVKENLDELSRRNIDVMHLQHILTNHLAFA
                     NVQQTPLFQLQQVNSQISELSRDELRSILSDAKCVGVIYRHGKDAAGKPLDEEYFYDL
                     ENDDDYERRNLVSSLKGGRTGLRSCRRTHKQYFWKKPAK"
     gene            <522663..>523288
                     /gene="RPL37A"
                     /locus_tag="YLR185W"
                     /db_xref="GeneID:850882"
     mRNA            join(<522663..522669,523029..>523288)
                     /gene="RPL37A"
                     /locus_tag="YLR185W"
                     /product="ribosomal 60S subunit protein L37A"
                     /transcript_id="NM_001182072.1"
                     /db_xref="GI:296146724"
                     /db_xref="GeneID:850882"
     CDS             join(522663..522669,523029..523288)
                     /gene="RPL37A"
                     /locus_tag="YLR185W"
                     /note="Ribosomal 60S subunit protein L37A; homologous to
                     mammalian ribosomal protein L37, no bacterial homolog;
                     RPL37A has a paralog, RPL37B, that arose from the whole
                     genome duplication"
                     /codon_start=1
                     /product="ribosomal 60S subunit protein L37A"
                     /protein_id="NP_013286.1"
                     /db_xref="GI:6323214"
                     /db_xref="SGD:S000004175"
                     /db_xref="GeneID:850882"
                     /translation="MGKGTPSFGKRHNKSHTLCNRCGRRSFHVQKKTCSSCGYPAAKT
                     RSYNWGAKAKRRHTTGTGRMRYLKHVSRRFKNGFQTGSASKASA"
     gene            <523632..>524390
                     /gene="EMG1"
                     /locus_tag="YLR186W"
                     /gene_synonym="NEP1"
                     /db_xref="GeneID:850883"
     mRNA            <523632..>524390
                     /gene="EMG1"
                     /locus_tag="YLR186W"
                     /gene_synonym="NEP1"
                     /product="Emg1p"
                     /transcript_id="NM_001182073.1"
                     /db_xref="GI:296146725"
                     /db_xref="GeneID:850883"
     CDS             523632..524390
                     /gene="EMG1"
                     /locus_tag="YLR186W"
                     /gene_synonym="NEP1"
                     /EC_number="2.1.1.260"
                     /note="Methyltransferase for rRNA; catalyzes methylation
                     of the pseudouridine residue 1191 of 18S rRNA; member of
                     the SPOUT methyltransferase family; required for
                     maturation of 18S rRNA and for 40S ribosomal subunit
                     production independently of methyltransferase activity;
                     forms homodimers; human ortholog is mutated in
                     Bowen-Conradi syndrome, and the equivalent mutation in
                     yeast affects Emg1p dimerization and localization but not
                     its methyltransferase activity"
                     /codon_start=1
                     /product="Emg1p"
                     /protein_id="NP_013287.1"
                     /db_xref="GI:6323215"
                     /db_xref="SGD:S000004176"
                     /db_xref="GeneID:850883"
                     /translation="MVEDSRVRDALKGGDQKALPASLVPQAPPVLTSKDKITKRMIVV
                     LAMASLETHKISSNGPGGDKYVLLNCDDHQGLLKKMGRDISEARPDITHQCLLTLLDS
                     PINKAGKLQVYIQTSRGILIEVNPTVRIPRTFKRFSGLMVQLLHKLSIRSVNSEEKLL
                     KVIKNPITDHLPTKCRKVTLSFDAPVIRVQDYIEKLDDDESICVFVGAMARGKDNFAD
                     EYVDEKVGLSNYPLSASVACSKFCHGAEDAWNIL"
     gene            <524865..>527945
                     /gene="SKG3"
                     /locus_tag="YLR187W"
                     /db_xref="GeneID:850884"
     mRNA            <524865..>527945
                     /gene="SKG3"
                     /locus_tag="YLR187W"
                     /product="Skg3p"
                     /transcript_id="NM_001182074.1"
                     /db_xref="GI:296146726"
                     /db_xref="GeneID:850884"
     CDS             524865..527945
                     /gene="SKG3"
                     /locus_tag="YLR187W"
                     /note="hypothetical protein; green fluorescent protein
                     (GFP)-fusion protein localizes to the cell periphery,
                     cytoplasm, bud, and bud neck; potential Cdc28p substrate;
                     similar to Skg4p; relocalizes from bud neck to cytoplasm
                     upon DNA replication stress; SKG3 has a paralog, CAF120,
                     that arose from the whole genome duplication"
                     /codon_start=1
                     /product="Skg3p"
                     /protein_id="NP_013288.1"
                     /db_xref="GI:6323216"
                     /db_xref="SGD:S000004177"
                     /db_xref="GeneID:850884"
                     /translation="MKRIFSGVKSPKLSAPPKVFKNDESPSTPSSPKFDQGLRSLSAS
                     ASRLFSNSISTPGSPTLDLPQEHSINGDISPELVPIVTLLSAQAHRRYHYGIFLILHD
                     LKTDGTPAARQWEECYGVLLGTQLALWDAKELSDSKNNKNTSTMKKAASRPSFINFTD
                     ASVRSLDANDQVIIASENEKTKKDLDNVLVVSTTLKNRYFLKFKNSKSFKTWNAAIRL
                     SLFEFTALQEAYTGSFLSSRGVKLGDIKVVMADTKFTYEDWVSVRFGTGMPWKRCYAV
                     ISPQSGKKKKNSKGSICFYENNKKTKKSNIMTTVVDARALYAVYPSSPILIDTSTIIK
                     LEGFVSFDKSEEPQETNLFIMPEKHQGVPGYDTIIRFLIPAMNAFYLYGRPKGLIANR
                     TDPDSLLFALPTLPHIYYLQVDDVLSLTKDKNYIHWSAADWRNNIVQVLQKKLSKGYK
                     GCGNKTVSVSSGMMKSPAISSAELFEGYDSLPERQMESPQKSKMKSPTLASTDDINSA
                     SASVNSHATSVKQTELFVTDNSSKINDSVSAQSSVTTNFKDTFTTPMTSGMLNHENSE
                     RSFGSGLKLKITDSNLENMEDVEAKSANEFSTTPEDKHIHLANAAELSALYDKYSTSP
                     FGKSEANSSPKPQKLEVKDRSKNENRSPYERYVGTSAESKTFEIGNVRESKSTINTSL
                     SSPLRVEDSRRSKNEDLGSLKEFEELSQKISNMGMANISSEALSDTAENSSFVTDLNL
                     NINNSSSVNLNEEQRVPDFGEENVFDPDYMEQNQMLETESRYTTDEFDFSDNQDAASS
                     NYSNGQTNRTVTETLSASDRNDKIPHSSLFTNLNQLTSNGGNYQDREDFSGDQINKPQ
                     QSQPLHVKGPQTSSFGYRNSSANSSQPQAPYPVGRPLGKIRTGPLTVQPMQQGGNSSM
                     YSFQSSQHRFHSSQQRQNQSLSFRNNTYGSGNNQNTFHPSPQLQQQPQNMRYLNNKLP
                     INDRSPIPQTQHHVPDGRPSLHINTTNRTNPLTAQSGFSQFMPPNSTSTNPYSS"
     gene            <528300..>530387
                     /gene="MDL1"
                     /locus_tag="YLR188W"
                     /db_xref="GeneID:850885"
     mRNA            <528300..>530387
                     /gene="MDL1"
                     /locus_tag="YLR188W"
                     /product="ATP-binding cassette permease MDL1"
                     /transcript_id="NM_001182075.1"
                     /db_xref="GI:296146727"
                     /db_xref="GeneID:850885"
     CDS             528300..530387
                     /gene="MDL1"
                     /locus_tag="YLR188W"
                     /note="Mitochondrial inner membrane half-type ABC
                     transporter; mediates export of peptides generated upon
                     proteolysis of mitochondrial proteins; plays a role in the
                     regulation of cellular resistance to oxidative stress"
                     /codon_start=1
                     /product="ATP-binding cassette permease MDL1"
                     /protein_id="NP_013289.1"
                     /db_xref="GI:6323217"
                     /db_xref="SGD:S000004178"
                     /db_xref="GeneID:850885"
                     /translation="MIVRMIRLCKGPKLLRSQFASASALYSTKSLFKPPMYQKAEINL
                     IIPHRKHFLLRSIRLQSDIAQGKKSTKPTLKLSNANSKSSGFKDIKRLFVLSKPESKY
                     IGLALLLILISSSVSMAVPSVIGKLLDLASESDGEDEEGSKSNKLYGFTKKQFFTALG
                     AVFIIGAVANASRIIILKVTGERLVARLRTRTMKAALDQDATFLDTNRVGDLISRLSS
                     DASIVAKSVTQNVSDGTRAIIQGFVGFGMMSFLSWKLTCVMMILAPPLGAMALIYGRK
                     IRNLSRQLQTSVGGLTKVAEEQLNATRTIQAYGGEKNEVRRYAKEVRNVFHIGLKEAV
                     TSGLFFGSTGLVGNTAMLSLLLVGTSMIQSGSMTVGELSSFMMYAVYTGSSLFGLSSF
                     YSELMKGAGAAARVFELNDRKPLIRPTIGKDPVSLAQKPIVFKNVSFTYPTRPKHQIF
                     KDLNITIKPGEHVCAVGPSGSGKSTIASLLLRYYDVNSGSIEFGDEDIRNFNLRKYRR
                     LIGYVQQEPLLFNGTILDNILYCIPPEIAEQDDRIRRAIGKANCTKFLANFPDGLQTM
                     VGARGAQLSGGQKQRIALARAFLLDPAVLILDEATSALDSQSEEIVAKNLQRRVERGF
                     TTISIAHRLSTIKHSTRVIVLGKHGSVVETGSFRDLIAIPNSELNALLAEQQDEEGKG
                     GVIDLDNSVAREV"
     gene            complement(<530797..>534393)
                     /gene="ATG26"
                     /locus_tag="YLR189C"
                     /gene_synonym="UGT51"
                     /db_xref="GeneID:850886"
     mRNA            complement(<530797..>534393)
                     /gene="ATG26"
                     /locus_tag="YLR189C"
                     /gene_synonym="UGT51"
                     /product="Atg26p"
                     /transcript_id="NM_001182076.1"
                     /db_xref="GI:296146728"
                     /db_xref="GeneID:850886"
     CDS             complement(530797..534393)
                     /gene="ATG26"
                     /locus_tag="YLR189C"
                     /gene_synonym="UGT51"
                     /EC_number="2.4.1.173"
                     /note="UDP-glucose:sterol glucosyltransferase; conserved
                     enzyme involved in synthesis of sterol glucoside membrane
                     lipids; in contrast to ATG26 from P. pastoris, S.
                     cerevisiae ATG26 is not involved in autophagy"
                     /codon_start=1
                     /product="Atg26p"
                     /protein_id="NP_013290.1"
                     /db_xref="GI:6323218"
                     /db_xref="SGD:S000004179"
                     /db_xref="GeneID:850886"
                     /translation="MPITQIISASDSEAGPKPSISLVPDKPSEPETSPRHHRLSRSLS
                     KFKRWRGRSNSSLSMGSSEQQELQDSPNEARSDDDENGYNNDNADDLAKSKYMMKSIA
                     GLLTTASVYAGMNNAQEMNVLSQVDSEESDSSDSFQENIGRNEVKSKKENLKTKSHPE
                     VPRLDKRKPTLFDFSITREKLSKDNVAKLRQRFCLDEQEPFLNDFPAWLLKDVLVQGH
                     IFITTKHFLFFAYLPKNPRSVKMSGNLNIRTKLIRSTRYWCVLKNHLFSMYTSSTELY
                     FPVLTIDLREVQKIETQKHTLNGSATKTFKLYTDESTFKFNADSEFSAKSWVNALKKE
                     QFAAQNSENNSISLKIPLPNIIEIDDQPIVNKALTLRLRALESSQTYAIDDFMFVFMD
                     GSGSQVKESLGEQLAILQKSGVNTLYYDIPAKKSKSSFGKETPATVEQKNNGEDSKYL
                     NVPTSAVPSSENGKKSRFRFRERSNSWFRRAKPLEDSQVEDVEEIYKDAANDIDSSVH
                     STIHIHEQEDSQEQTVAWKPSHLKNFAEMWAAKPIHYRNKFIPFQKDDTYLIKETEEV
                     SANERFRYHFKFNKEKSLISTYYTYLNRNVPVYGKIYVSNDTVCFRSLLPGSNTYMVL
                     PLVDVETCYKEKGFRFGYFVLVIVIHGHEELFFEFSTEVARDDIERILLKLLDNIYAS
                     SAEGSNISSASLGDVQHNPDSAKLKLFEDKINAEGFEVPLMIDENPHYKTSIKPNKSY
                     KFGLLTIGSRGDVQPYIALGKGLIKEGHQVVIITHSEFRDFVESHGIQFEEIAGNPVE
                     LMSLMVENESMNVKMLREASSKFRGWIDALLQTSWEVCNRRKFDILIESPSAMVGIHI
                     TEALQIPYFRAFTMPWTRTRAYPHAFIVPDQKRGGNYNYLTHVLFENVFWKGISGQVN
                     KWRVETLGLGKTNLFLLQQNNVPFLYNVSPTIFPPSIDFSEWVRVTGYWFLDDKSTFK
                     PPAELQEFISEARSKGKKLVYIGFGSIVVSNAKEMTEALVEAVMEADVYCILNKGWSE
                     RLGDKAAKKTEVDLPRNILNIGNVPHDWLFPQVDAAVHHGGSGTTGASLRAGLPTVIK
                     PFFGDQFFYAGRVEDIGVGIALKKLNAQTLADALKVATTNKIMKDRAGLIKKKISKED
                     GIKTAISAIYNELEYARSVTLSRVKTPRKKEENVDATKLTPAETTDEGWTMI"
     gene            <535214..>536689
                     /gene="MMR1"
                     /locus_tag="YLR190W"
                     /db_xref="GeneID:850887"
     mRNA            <535214..>536689
                     /gene="MMR1"
                     /locus_tag="YLR190W"
                     /product="Mmr1p"
                     /transcript_id="NM_001182077.1"
                     /db_xref="GI:296146729"
                     /db_xref="GeneID:850887"
     CDS             535214..536689
                     /gene="MMR1"
                     /locus_tag="YLR190W"
                     /note="Phosphorylated protein of the mitochondrial outer
                     membrane; localizes only to mitochondria of the bud;
                     interacts with Myo2p to mediate mitochondrial distribution
                     to buds; mRNA is targeted to the bud via the transport
                     system involving She2p"
                     /codon_start=1
                     /product="Mmr1p"
                     /protein_id="NP_013291.1"
                     /db_xref="GI:6323219"
                     /db_xref="SGD:S000004180"
                     /db_xref="GeneID:850887"
                     /translation="MNSPTMKSEQLTPKLSPMSFCLDDQRNAGSFQNLLNSPTKLKLD
                     TGPIGNSLLYPTSLSKLSELSRGGRSKQRRGSDTMRSVSPIRFQFLNNTPKMLKPEYL
                     SQTTSNLPLLSALLKNSKKTTSEGQNSNPDPLNIEKNIIKQSIKDKLEQLRSSESVAQ
                     VQKKERNPPSFEAKVCAEEPILRKNAEGLLPSYVPVPATPLEDPENHGVRKVEDKGLR
                     VVSGGSTQCLSTEVNELPKDLNLDNLPTDNNGFVQYGLKGNNNNNRYSFISSTSTDYE
                     PEWCDGQQHISMQMASMANAEEANSREKSNLDIKIKQLELEITELKLQNEKLVHSMTT
                     NRYIEERFMLEVMKDPSIQAQRSQRDIERKVKQLEKKFFNCKKVLKKLTESSAVVATS
                     TSKTEGNSARIPCPKTRLARVSVLDLKKIEEQPDSSSGTSSEEDHLTNDDTDANTSED
                     LNVAFEEEPTSAISTTASVQSGESKRGFQLNLPVQVEKKEK"
     gene            <537272..>538432
                     /gene="PEX13"
                     /locus_tag="YLR191W"
                     /gene_synonym="PAS20"
                     /db_xref="GeneID:850888"
     mRNA            <537272..>538432
                     /gene="PEX13"
                     /locus_tag="YLR191W"
                     /gene_synonym="PAS20"
                     /product="Pex13p"
                     /transcript_id="NM_001182078.1"
                     /db_xref="GI:296146730"
                     /db_xref="GeneID:850888"
     CDS             537272..538432
                     /gene="PEX13"
                     /locus_tag="YLR191W"
                     /gene_synonym="PAS20"
                     /note="Integral peroxisomal membrane protein; required for
                     translocation of peroxisomal matrix proteins; interacts
                     with the PTS1 signal recognition factor Pex5p and the PTS2
                     signal recognition factor Pex7p; forms a complex with
                     Pex14p and Pex17p"
                     /codon_start=1
                     /product="Pex13p"
                     /protein_id="NP_013292.1"
                     /db_xref="GI:6323220"
                     /db_xref="SGD:S000004181"
                     /db_xref="GeneID:850888"
                     /translation="MSSTAVPRPKPWETSASLEEPQRNAQSLSAMMTSNQQDSRPTEE
                     SNNSNSASESAPEVLPRPAALNSSGTYGESNTIPGIYGNSNYGIPYDNNPYSMNSIYG
                     NSIGRYGYGGSYYGNNYGSFYGGGYGAGAGYGMNNGSGLGESTKATFQLIESLIGAVT
                     GFAQMLESTYMATHNSFFTMISVAEQFGNLKEMLGSFFGIFAIMKFLKKILYRATKGR
                     LGIPPKNFAESEGSKNKLIEDFQKFNDSGTINSNEKATRRKISWKPLLFFLMAVFGFP
                     YLLNKFITKLQTSGTIRASQGNGSEPIDPSKLEFARALYDFVPENPEMEVALKKGDLM
                     AILSKKDPLGRDSDWWKVRTKNGNIGYIPYNYIEIIKRRKKIEHVDDETRTH"
     gene            complement(<538792..>539589)
                     /gene="HCR1"
                     /locus_tag="YLR192C"
                     /db_xref="GeneID:850889"
     mRNA            complement(<538792..>539589)
                     /gene="HCR1"
                     /locus_tag="YLR192C"
                     /product="Hcr1p"
                     /transcript_id="NM_001182079.1"
                     /db_xref="GI:296146731"
                     /db_xref="GeneID:850889"
     CDS             complement(538792..539589)
                     /gene="HCR1"
                     /locus_tag="YLR192C"
                     /note="eIF3j component of translation initiation factor 3
                     (eIF3); dual function protein involved in translation
                     initiation as a substoichiometric component (eIF3j) of
                     eIF3; required for processing of 20S pre-rRNA; required at
                     post-transcriptional step for efficient
                     retrotransposition; absence results in decreased Ty1
                     Gag:GFP protein levels; binds to eIF3 subunits Rpg1p and
                     Prt1p and 18S rRNA"
                     /codon_start=1
                     /product="Hcr1p"
                     /protein_id="NP_013293.1"
                     /db_xref="GI:6323221"
                     /db_xref="SGD:S000004182"
                     /db_xref="GeneID:850889"
                     /translation="MSWDDEAINGSMGNDDAVLMDSWDAEIGDDEPVMQSWDAEEEEK
                     KPAPKPKKEQPKKVKKGKESSADRALLDIDTLDEKTRKELIKKAEMESDLNNAADLFA
                     GLGVAEEHPRARALQKEQEEQALKRPAFTKDTPIETHPLFNAETKREYQDLRKALTAA
                     ITPMNKKSPLNYSSSLAIDLIRDVAKPMSIESIRQTVATLNVLIKDKEREERQARLAR
                     VRGGTATGGAGKKKVKGKTNLGGAFKKDQDFDLDGPDDFEFGDDDFM"
     gene            complement(<540009..>540536)
                     /gene="UPS1"
                     /locus_tag="YLR193C"
                     /db_xref="GeneID:850890"
     mRNA            complement(<540009..>540536)
                     /gene="UPS1"
                     /locus_tag="YLR193C"
                     /product="Ups1p"
                     /transcript_id="NM_001182080.1"
                     /db_xref="GI:296146732"
                     /db_xref="GeneID:850890"
     CDS             complement(540009..540536)
                     /gene="UPS1"
                     /locus_tag="YLR193C"
                     /note="Phosphatidic acid transfer protein; plays a role in
                     phospholipid metabolism by transporting phosphatidic acid
                     from the outer to the inner mitochondrial membrane;
                     localizes to the mitochondrial intermembrane space; null
                     mutant has altered cardiolipin and phosphatidic acid
                     levels; ortholog of human PRELI"
                     /codon_start=1
                     /product="Ups1p"
                     /protein_id="NP_013294.1"
                     /db_xref="GI:6323222"
                     /db_xref="SGD:S000004183"
                     /db_xref="GeneID:850890"
                     /translation="MVLLHKSTHIFPTDFASVSRAFFNRYPNPYSPHVLSIDTISRNV
                     DQEGNLRTTRLLKKSGKLPTWVKPFLRGITETWIIEVSVVNPANSTMKTYTRNLDHTG
                     IMKVEEYTTYQFDSATSSTIADSRVKFSSGFNMGIKSKVEDWSRTKFDENVKKSRMGM
                     AFVIQKLEEARNPQF"
     gene            complement(<540809..>541573)
                     /locus_tag="YLR194C"
                     /db_xref="GeneID:850891"
     mRNA            complement(<540809..>541573)
                     /locus_tag="YLR194C"
                     /product="hypothetical protein"
                     /transcript_id="NM_001182081.1"
                     /db_xref="GI:296146733"
                     /db_xref="GeneID:850891"
     CDS             complement(540809..541573)
                     /locus_tag="YLR194C"
                     /note="Structural constituent of the cell wall; attached
                     to the plasma membrane by a GPI-anchor; expression is
                     upregulated in response to cell wall stress"
                     /codon_start=1
                     /product="hypothetical protein"
                     /protein_id="NP_013295.1"
                     /db_xref="GI:6323223"
                     /db_xref="SGD:S000004184"
                     /db_xref="GeneID:850891"
                     /translation="MKACSILFTTLITLAAAQKDSGSLDGQNSEDSSQKESSNSQEIT
                     PTTTKEAQESASTVVSTGKSLVQTSNVVSNTYAVAPSTTVVTTDAQGKTTTQYLWWVA
                     ESNSAVSTTSTASVQPTGETSSGITNSASSSTTSTSTDGPVTIVTTTNSLGETYTSTV
                     WWLPSSATTDNTASSSKSSSGSSSKPESSTKVVSTIKSTYTTTSGSTVETLTTTYKST
                     VNGKVASVMSNSTNGAFAGTHIAYGAGAFAVGALLL"
     gene            complement(<541937..>543304)
                     /gene="NMT1"
                     /locus_tag="YLR195C"
                     /gene_synonym="CDC72"
                     /db_xref="GeneID:850892"
     mRNA            complement(<541937..>543304)
                     /gene="NMT1"
                     /locus_tag="YLR195C"
                     /gene_synonym="CDC72"
                     /product="glycylpeptide N-tetradecanoyltransferase NMT1"
                     /transcript_id="NM_001182082.1"
                     /db_xref="GI:296146734"
                     /db_xref="GeneID:850892"
     CDS             complement(541937..543304)
                     /gene="NMT1"
                     /locus_tag="YLR195C"
                     /gene_synonym="CDC72"
                     /EC_number="2.3.1.97"
                     /note="N-myristoyl transferase; catalyzes the
                     cotranslational, covalent attachment of myristic acid to
                     the N-terminal glycine residue of several proteins
                     involved in cellular growth and signal transduction"
                     /codon_start=1
                     /product="glycylpeptide N-tetradecanoyltransferase NMT1"
                     /protein_id="NP_013296.1"
                     /db_xref="GI:6323224"
                     /db_xref="SGD:S000004185"
                     /db_xref="GeneID:850892"
                     /translation="MSEEDKAKKLENLLKLLQLNNDDTSKFTQEQKKAMKDHKFWRTQ
                     PVKDFDEKVVEEGPIDKPKTPEDISDKPLPLLSSFEWCSIDVDNKKQLEDVFVLLNEN
                     YVEDRDAGFRFNYTKEFFNWALKSPGWKKDWHIGVRVKETQKLVAFISAIPVTLGVRG
                     KQVPSVEINFLCVHKQLRSKRLTPVLIKEITRRVNKCDIWHALYTAGIVLPAPVSTCR
                     YTHRPLNWKKLYEVDFTGLPDGHTEEDMIAENALPAKTKTAGLRKLKKEDIDQVFELF
                     KRYQSRFELIQIFTKEEFEHNFIGEESLPLDKQVIFSYVVEQPDGKITDFFSFYSLPF
                     TILNNTKYKDLGIGYLYYYATDADFQFKDRFDPKATKALKTRLCELIYDACILAKNAN
                     MDVFNALTSQDNTLFLDDLKFGPGDGFLNFYLFNYRAKPITGGLNPDNSNDIKRRSNV
                     GVVML"
     gene            <543968..>545698
                     /gene="PWP1"
                     /locus_tag="YLR196W"
                     /db_xref="GeneID:850893"
     mRNA            <543968..>545698
                     /gene="PWP1"
                     /locus_tag="YLR196W"
                     /product="Pwp1p"
                     /transcript_id="NM_001182083.1"
                     /db_xref="GI:296146735"
                     /db_xref="GeneID:850893"
     CDS             543968..545698
                     /gene="PWP1"
                     /locus_tag="YLR196W"
                     /note="Protein with WD-40 repeats involved in rRNA
                     processing; associates with trans-acting ribosome
                     biogenesis factors; similar to beta-transducin
                     superfamily"
                     /codon_start=1
                     /product="Pwp1p"
                     /protein_id="NP_013297.1"
                     /db_xref="GI:6323225"
                     /db_xref="SGD:S000004186"
                     /db_xref="GeneID:850893"
                     /translation="MISATNWVPRGFSSEFPEKYVLDDEEVERINQLAQLNLDDAKAT
                     LEEAEGESGVEDDAATGSSNKLKDQLDIDDDLKEYNLEEYDDEEIADNEGGKDVSMFP
                     GLSNDSDVKFHEGEKGEDPYISLPNQEDSQEEKQELQVYPSDNLVLAARTEDDVSYLD
                     IYVYDDGAGFHSSDIPVEEGDEADPDVARGLVRDPALYVHHDLMLPAFPLCVEWLDYK
                     VGSNSEEAANYAAIGTFDPQIEIWNLDCVDKAFPDMILGEPLDNSMVSLKSKKKKKKS
                     KTGHITTHHTDAVLSMAHNKYFRSVLASTSADHTVKLWDLNSGNAARSLASIHSNKNV
                     SSSEWHMLNGSILLTGGYDSRVALTDVRISDESQMSKYWSAMAGEEIETVTFASENII
                     LCGTDSGNVYSFDIRNNENRKPVWTLKAHDAGISTLCSNKFIPGMMSTGAMGEKTVKL
                     WKFPLDDATNTKGPSMVLSRDFDVGNVLTSSFAPDIEVAGTMVIGGVNKVLKLWDVFT
                     NRSVRKSFKSELENVQARAKEEAQKIGKSSRIARKYTSNDNPDTVITIDDQGEDEEER
                     EGGDEHDDMA"
     gene            <546097..>547611
                     /gene="NOP56"
                     /locus_tag="YLR197W"
                     /gene_synonym="SIK1"
                     /db_xref="GeneID:850894"
     mRNA            <546097..>547611
                     /gene="NOP56"
                     /locus_tag="YLR197W"
                     /gene_synonym="SIK1"
                     /product="snoRNP complex protein NOP56"
                     /transcript_id="NM_001182084.1"
                     /db_xref="GI:296146736"
                     /db_xref="GeneID:850894"
     CDS             546097..547611
                     /gene="NOP56"
                     /locus_tag="YLR197W"
                     /gene_synonym="SIK1"
                     /note="Essential evolutionarily-conserved nucleolar
                     protein; component of the box C/D snoRNP complexes that
                     direct 2'-O-methylation of pre-rRNA during its maturation;
                     overexpression causes spindle orientation defects"
                     /codon_start=1
                     /product="snoRNP complex protein NOP56"
                     /protein_id="NP_013298.1"
                     /db_xref="GI:6323226"
                     /db_xref="SGD:S000004187"
                     /db_xref="GeneID:850894"
                     /translation="MAPIEYLLFEEPTGYAVFKVKLQQDDIGSRLKEVQEQINDFGAF
                     TKLIELVSFAPFKGAAEALENANDISEGLVSESLKAILDLNLPKASSKKKNITLAISD
                     KNLGPSIKEEFPYVDCISNELAQDLIRGVRLHGEKLFKGLQSGDLERAQLGLGHAYSR
                     AKVKFSVQKNDNHIIQAIALLDQLDKDINTFAMRVKEWYGWHFPELAKLVPDNYTFAK
                     LVLFIKDKASLNDDSLHDLAALLNEDSGIAQRVIDNARISMGQDISETDMENVCVFAQ
                     RVASLADYRRQLYDYLCEKMHTVAPNLSELIGEVIGARLISHAGSLTNLSKQAASTVQ
                     ILGAEKALFRALKTKGNTPKYGLIYHSGFISKASAKNKGRISRYLANKCSMASRIDNY
                     SEEPSNVFGSVLKKQVEQRLEFYNTGKPTLKNELAIQEAMELYNKDKPAAEVEETKEK
                     ESSKKRKLEDDDEEKKEKKEKKSKKEKKEKKEKKDKKEKKDKKEKKDKKKKSKD"
     gene            complement(<547853..>548769)
                     /gene="PBA1"
                     /locus_tag="YLR199C"
                     /gene_synonym="POC1"
                     /db_xref="GeneID:850896"
     mRNA            complement(join(<547853..548677,548764..>548769))
                     /gene="PBA1"
                     /locus_tag="YLR199C"
                     /gene_synonym="POC1"
                     /product="Pba1p"
                     /transcript_id="NM_001182086.1"
                     /db_xref="GI:296146737"
                     /db_xref="GeneID:850896"
     CDS             complement(join(547853..548677,548764..548769))
                     /gene="PBA1"
                     /locus_tag="YLR199C"
                     /gene_synonym="POC1"
                     /note="Protein involved in 20S proteasome assembly; forms
                     a heterodimer with Add66p that binds to proteasome
                     precursors; interaction with Pba1p-Add66p may affect
                     function of the mature proteasome and its role in
                     maintaining respiratory metabolism; similar to human PAC1
                     constituent of the PAC1-PAC2 complex involved in
                     proteasome assembly"
                     /codon_start=1
                     /product="Pba1p"
                     /protein_id="NP_013300.2"
                     /db_xref="GI:37362679"
                     /db_xref="SGD:S000004189"
                     /db_xref="GeneID:850896"
                     /translation="MLFKQWNDLPEPKHLLDLPEISKNLQSLEVCPVPKVEFPQDLDV
                     PQYSTAVITTKIMNPLFPKNLLQLTSIGEIKTTLTVKSPSLPQSSGKHSWNYDENFPN
                     EVDPDQKNDTADETVYGFSFPIYSFGKTLLFSMEENFISISPIFGNMISRSIISQLAQ
                     FSPDIIVIGTSDKIASMKVMTENECTLQPPEFITGFIGSVLTQLIVGPSKGLKFKCLV
                     APSEGPNGFEKLSLSDMGSLVDLCGQWLGFEPSRYSEECYRLWRCDSAAIGAQSGLYI
                     "
     gene            <549012..>549356
                     /gene="YKE2"
                     /locus_tag="YLR200W"
                     /gene_synonym="GIM1; PFD6"
                     /db_xref="GeneID:850897"
     mRNA            <549012..>549356
                     /gene="YKE2"
                     /locus_tag="YLR200W"
                     /gene_synonym="GIM1; PFD6"
                     /product="Yke2p"
                     /transcript_id="NM_001182087.1"
                     /db_xref="GI:296146738"
                     /db_xref="GeneID:850897"
     CDS             549012..549356
                     /gene="YKE2"
                     /locus_tag="YLR200W"
                     /gene_synonym="GIM1; PFD6"
                     /note="Subunit of the heterohexameric Gim/prefoldin
                     protein complex; involved in the folding of alpha-tubulin,
                     beta-tubulin, and actin; prefoldin complex also localizes
                     to chromatin of actively transcribed genes in the nucleus
                     and facilitates transcriptional elongation"
                     /codon_start=1
                     /product="Yke2p"
                     /protein_id="NP_013301.1"
                     /db_xref="GI:6323229"
                     /db_xref="SGD:S000004190"
                     /db_xref="GeneID:850897"
                     /translation="MSELGAKYQQLQNELEEFIVARQKLETQLQENKIVNEEFDQLEE
                     DTPVYKLTGNVLLPVEQSEARTNVDKRLEFIETEITRCEKNIRDKQEELEKMRSELIK
                     LNNTAASTGPGR"
     gene            complement(<549511..>550293)
                     /gene="COQ9"
                     /locus_tag="YLR201C"
                     /db_xref="GeneID:850898"
     mRNA            complement(<549511..>550293)
                     /gene="COQ9"
                     /locus_tag="YLR201C"
                     /product="Coq9p"
                     /transcript_id="NM_001182088.1"
                     /db_xref="GI:296146739"
                     /db_xref="GeneID:850898"
     CDS             complement(549511..550293)
                     /gene="COQ9"
                     /locus_tag="YLR201C"
                     /note="Protein required for ubiquinone biosynthesis and
                     respiratory growth; localizes to the matrix face of the
                     mitochondrial inner membrane in a large complex with
                     ubiquinone biosynthetic enzymes; ubiquinone is also known
                     as coenzyme Q"
                     /codon_start=1
                     /product="Coq9p"
                     /protein_id="NP_013302.1"
                     /db_xref="GI:6323230"
                     /db_xref="SGD:S000004191"
                     /db_xref="GeneID:850898"
                     /translation="MLCRNTARTGCKFFRLYHSNPIEHVKPIHIKPLTYGKESPQYKV
                     LSLALQKFVPEHGFSERSIVESLNELGYPSSMISSIGAPNSPSFFHSSTAVMELIKFQ
                     LVDKRYRLTEGINPDVTPQYKLPSLEHLLLKRLEMDKPIGGHLSELMSQLAIPSAFLF
                     ETAIPELHRLSDDMIYFSNEKDHHDSAWYAKRLAVSSTYIGSKLFMAQDKSHNYKETF
                     TFAKDKLHRVMRLGEYYNNTEEFAWYTLMSTVNLIKSQLVRG"
     gene            complement(<550650..>551960)
                     /gene="MSS51"
                     /locus_tag="YLR203C"
                     /db_xref="GeneID:850900"
     mRNA            complement(<550650..>551960)
                     /gene="MSS51"
                     /locus_tag="YLR203C"
                     /product="Mss51p"
                     /transcript_id="NM_001182090.1"
                     /db_xref="GI:296146740"
                     /db_xref="GeneID:850900"
     CDS             complement(550650..551960)
                     /gene="MSS51"
                     /locus_tag="YLR203C"
                     /note="Specific translational activator for the
                     mitochondrial COX1 mRNA; loosely associated with the
                     matrix face of the mitochondrial inner membrane; localizes
                     to vacuole membrane in response to H2O2; influences both
                     COX1 mRNA translation and Cox1p assembly into cytochrome c
                     oxidase; binds to heme B, which may be a mechanism for
                     sensing oxygen levels in order to regulate cytochrome c
                     oxidase biogenesis"
                     /codon_start=1
                     /product="Mss51p"
                     /protein_id="NP_013304.1"
                     /db_xref="GI:6323232"
                     /db_xref="SGD:S000004193"
                     /db_xref="GeneID:850900"
                     /translation="MTVLYAPSGATQLYFHLLRKSPHNRLVVSHQTRRHLMGFVRNAL
                     GLDPPPSPEDPTPENRFHPWDQSPSVDLRERAAKIRTLAHCPVTGKDINYTCPLSGIP
                     THHSREAWEMDKAYHDSKKYEILKKVNIYEHDLRSGRPFPEFDFPQQQGYDKAVNLTN
                     WDLFFYTRSFYSMDTEFQLAAVTKMLSYPITIGSLLHKFSPYSLNPKGPITLEGLKSL
                     AALRYTLYPLENRSLPTTTKNRAMRIFILGARAEAQLPGHVWKQLQFLFPEQSFEIHF
                     IGPECLYKRDKQEYVKSTTPVVQRVDETLKFIYRTNFFEVFHEAQDFFPYDPYMDVFF
                     TFHPGYASPESHGSWMGETMKALLETKCAIFTTGFNKKDLTDDINLVKSKYGKEMDVL
                     MEPVRNVFGSTKWELNDMNPQEVYQFNMYIAGFRGKRYHTIKRQ"
     gene            <552270..>552605
                     /gene="QRI5"
                     /locus_tag="YLR204W"
                     /gene_synonym="COX24"
                     /db_xref="GeneID:850901"
     mRNA            <552270..>552605
                     /gene="QRI5"
                     /locus_tag="YLR204W"
                     /gene_synonym="COX24"
                     /product="Qri5p"
                     /transcript_id="NM_001182091.1"
                     /db_xref="GI:296146741"
                     /db_xref="GeneID:850901"
     CDS             552270..552605
                     /gene="QRI5"
                     /locus_tag="YLR204W"
                     /gene_synonym="COX24"
                     /note="Mitochondrial inner membrane protein; required for
                     accumulation of spliced COX1 mRNA; may have an additional
                     role in translation of COX1 mRNA"
                     /codon_start=1
                     /product="Qri5p"
                     /protein_id="NP_013305.1"
                     /db_xref="GI:6323233"
                     /db_xref="SGD:S000004194"
                     /db_xref="GeneID:850901"
                     /translation="MLGRALRPGWLGITRTVVKKPSCGSYFNRTFQTAINTTMPPMQE
                     GMLSTMMMMTATATRITGTVSEPLNGSNIVMQLDSVMRKRKKKMKKHKLRKRRKREKA
                     ERRKLSQGR"
     gene            complement(<552724..>553677)
                     /gene="HMX1"
                     /locus_tag="YLR205C"
                     /db_xref="GeneID:850902"
     mRNA            complement(<552724..>553677)
                     /gene="HMX1"
                     /locus_tag="YLR205C"
                     /product="Hmx1p"
                     /transcript_id="NM_001182092.1"
                     /db_xref="GI:296146742"
                     /db_xref="GeneID:850902"
     CDS             complement(552724..553677)
                     /gene="HMX1"
                     /locus_tag="YLR205C"
                     /note="ER localized heme oxygenase; involved in heme
                     degradation during iron starvation and in the oxidative
                     stress response; expression is regulated by AFT1 and
                     oxidative stress; relocates to the perinuclear region in
                     the presence of oxidants"
                     /codon_start=1
                     /product="Hmx1p"
                     /protein_id="NP_013306.2"
                     /db_xref="GI:42742287"
                     /db_xref="SGD:S000004195"
                     /db_xref="GeneID:850902"
                     /translation="MEDSSNTIIPSPTDVGALANRINFQTRDAHNKINTFMGIKMAIA
                     MRHGFIYRQGILAYYYVFDAIEQEIDRLLNDPVTEEELQTSTILKQFWLEDFRRSTQI
                     YKDLKLLYSNTFKSTESLNEFLATFQKPPLLQQFINNIHENIHKEPCTILSYCHVLYL
                     ALFAGGKLIRSNLYRRLGLFPNFEKLSQKELVKKGTNFFTFSDLGPTEETRLKWEYKK
                     NYELATRTELTEAQKLQIISVAEGIFDWNFNIVAEIGELNRRELMGKFSFKCITYLYE
                     EWMFNKDSATRRALHTVMLLVLSIIAIWVLYFLVKSFLSIV"
     gene            <554578..>556419
                     /gene="ENT2"
                     /locus_tag="YLR206W"
                     /db_xref="GeneID:850903"
     mRNA            <554578..>556419
                     /gene="ENT2"
                     /locus_tag="YLR206W"
                     /product="Ent2p"
                     /transcript_id="NM_001182093.1"
                     /db_xref="GI:296146743"
                     /db_xref="GeneID:850903"
     CDS             554578..556419
                     /gene="ENT2"
                     /locus_tag="YLR206W"
                     /note="Epsin-like protein required for endocytosis and
                     actin patch assembly; functionally redundant with Ent1p;
                     contains clathrin-binding motif at C-terminus; ENT2 has a
                     paralog, ENT1, that arose from the whole genome
                     duplication"
                     /codon_start=1
                     /product="Ent2p"
                     /protein_id="NP_013307.1"
                     /db_xref="GI:6323235"
                     /db_xref="SGD:S000004196"
                     /db_xref="GeneID:850903"
                     /translation="MSKQFVRSAKNMMKGYSSTQVLVRDATANDSRTPSIDTLDDLAQ
                     RSYDSVDFFEIMDMLDKRLNDKGKYWRHVAKSLTVLDYLVRFGSENCVLWCRENFYVI
                     KTLREFRHENESGFDEGQIIRVKAKELVSLLNDEERLREERSMNTRNRRANRAARPRP
                     RRQRTRSNPHDSSPSYQDDLEKALEESRITAQEDEQRRRELAQYDDEDPDFQAALQLS
                     KEEEELKQLQELQRLQKQQQSLSQFQAPLQQQQPQQQPAYYDIFGNPISQDEYLQYQY
                     QQDQEQAMAQQRWLDQQQEQQQLAEQQYFQQQQQAAAAASALQQQQTAANMQQQQQQP
                     ADFQQPLPTGSNNPFSMDNLERQKQEQQHAQLQRQQEEARQQQEQLKLQQLQRQQQEE
                     AQLHQKRQEEAQLQQQQAQLLQQQAQFQQQQPLKQTRTGNQSISDKYSDLNTLLATGT
                     GIDTFGNTGEARIPAQHTKTGTFINSQGTGYKQVTNEPKNNPFLSNQYTGLPSTNIVP
                     TQTGYGFGNQPQSPPTNSPQQNPTGISYSQPQQQQQPQQQPQYMQNFQQQQPQYAQNF
                     QQQPQYTQNYQQQPQYIQPHQQQQQQQQQQQQQQGYTPDQGVSLIDL"
     gene            <556788..>559289
                     /gene="HRD3"
                     /locus_tag="YLR207W"
                     /db_xref="GeneID:850904"
     mRNA            <556788..>559289
                     /gene="HRD3"
                     /locus_tag="YLR207W"
                     /product="ubiquitin ligase complex subunit HRD3"
                     /transcript_id="NM_001182094.1"
                     /db_xref="GI:296146744"
                     /db_xref="GeneID:850904"
     CDS             556788..559289
                     /gene="HRD3"
                     /locus_tag="YLR207W"
                     /note="ER membrane protein that plays a central role in
                     ERAD; forms HRD complex with Hrd1p and ER-associated
                     protein degradation (ERAD) determinants that engages in
                     lumen to cytosol communication and coordination of ERAD
                     events"
                     /codon_start=1
                     /product="ubiquitin ligase complex subunit HRD3"
                     /protein_id="NP_013308.1"
                     /db_xref="GI:6323236"
                     /db_xref="SGD:S000004197"
                     /db_xref="GeneID:850904"
                     /translation="MITLLLYLCVICNAIVLIRADSIADPWPEARHLLNTIAKSRDPM
                     KEAAMEPNADEFVGFYVPMDYSPRNEEKNYQSIWQNEITDSQRHIYELLVQSSEQFNN
                     SEATYTLSQIHLWSQYNFPHNMTLAHKYLEKFNDLTHFTNHSAIFDLAVMYATGGCAS
                     GNDQTVIPQDSAKALLYYQRAAQLGNLKAKQVLAYKYYSGFNVPRNFHKSLVLYRDIA
                     EQLRKSYSRDEWDIVFPYWESYNVRISDFESGLLGKGLNSVPSSTVRKRTTRPDIGSP
                     FIAQVNGVQMTLQIEPMGRFAFNGNDGNINGDEDDEDASERRIIRIYYAALNDYKGTY
                     SQSRNCERAKNLLELTYKEFQPHVDNLDPLQVFYYVRCLQLLGHMYFTGEGSSKPNIH
                     MAEEILTTSLEISRRAQGPIGRACIDLGLINQYITNNISQAISYYMKAMKTQANNGIV
                     EFQLSKLATSFPEEKIGDPFNLMETAYLNGFIPAIYEFAVMIESGMNSKSSVENTAYL
                     FKTFVDKNEAIMAPKLRTAFAALINDRSEVALWAYSQLAEQGYETAQVSAAYLMYQLP
                     YEFEDPPRTTDQRKTLAISYYTRAFKQGNIDAGVVAGDIYFQMQNYSKAMALYQGAAL
                     KYSIQAIWNLGYMHEHGLGVNRDFHLAKRYYDQVSEHDHRFYLASKLSVLKLHLKSWL
                     TWITREKVNYWKPSSPLNPNEDTQHSKTSWYKQLTKILQRMRHKEDSDKAAEDSHKHR
                     TVVQNGANHRGDDQEEASEILGFQMEDLVTMGCILGIFLLSILMSTLAARRGWNVRFN
                     GAQLNANGNRQQEQQQQQQAQGPPGWDFNVQIFAI"
     gene            <559551..>560444
                     /gene="SEC13"
                     /locus_tag="YLR208W"
                     /gene_synonym="ANU3"
                     /db_xref="GeneID:850905"
     mRNA            <559551..>560444
                     /gene="SEC13"
                     /locus_tag="YLR208W"
                     /gene_synonym="ANU3"
                     /product="GTPase-activating protein SEC13"
                     /transcript_id="NM_001182095.1"
                     /db_xref="GI:296146745"
                     /db_xref="GeneID:850905"
     CDS             559551..560444
                     /gene="SEC13"
                     /locus_tag="YLR208W"
                     /gene_synonym="ANU3"
                     /note="Structural component of 3 distinct complexes;
                     subunit of Nup84 nuclear pore sub-complex (NPC), COPII
                     vesicle coat, and Seh1-associated (SEA) complex; COPII
                     vesicle coat is required for ER to Golgi transport; the
                     Nup84 subcomplex contributes to nucleocytoplasmic
                     transport, NPC biogenesis and processes that may require
                     localization of chromosomes at the nuclear periphery,
                     including transcription; homologous to human SEC13;
                     abundance increases under DNA replication stress"
                     /codon_start=1
                     /product="GTPase-activating protein SEC13"
                     /protein_id="NP_013309.1"
                     /db_xref="GI:6323237"
                     /db_xref="SGD:S000004198"
                     /db_xref="GeneID:850905"
                     /translation="MVVIANAHNELIHDAVLDYYGKRLATCSSDKTIKIFEVEGETHK
                     LIDTLTGHEGPVWRVDWAHPKFGTILASCSYDGKVLIWKEENGRWSQIAVHAVHSASV
                     NSVQWAPHEYGPLLLVASSDGKVSVVEFKENGTTSPIIIDAHAIGVNSASWAPATIEE
                     DGEHNGTKESRKFVTGGADNLVKIWKYNSDAQTYVLESTLEGHSDWVRDVAWSPTVLL
                     RSYLASVSQDRTCIIWTQDNEQGPWKKTLLKEEKFPDVLWRASWSLSGNVLALSGGDN
                     KVTLWKENLEGKWEPAGEVHQ"
     gene            complement(<560797..>561732)
                     /gene="PNP1"
                     /locus_tag="YLR209C"
                     /db_xref="GeneID:850906"
     mRNA            complement(<560797..>561732)
                     /gene="PNP1"
                     /locus_tag="YLR209C"
                     /product="purine-nucleoside phosphorylase"
                     /transcript_id="NM_001182096.1"
                     /db_xref="GI:296146746"
                     /db_xref="GeneID:850906"
     CDS             complement(560797..561732)
                     /gene="PNP1"
                     /locus_tag="YLR209C"
                     /EC_number="2.4.2.1"
                     /note="Purine nucleoside phosphorylase; specifically
                     metabolizes inosine and guanosine nucleosides; involved in
                     the nicotinamide riboside salvage pathway"
                     /codon_start=1
                     /product="purine-nucleoside phosphorylase"
                     /protein_id="NP_013310.1"
                     /db_xref="GI:6323238"
                     /db_xref="SGD:S000004199"
                     /db_xref="GeneID:850906"
                     /translation="MSDILNVSQQREAITKAAAYISAILEPHFKNTTNFEPPRTLIIC
                     GSGLGGISTKLSRDNPPPVTVPYQDIPGFKKSTVPGHSGTLMFGSMNGSPVVLMNGRL
                     HGYEGNTLFETTFPIRVLNHMGHVRNLIVTNAAGGINAKYQACDLMCIYDHLNIPGLA
                     GQHPLRGPNLDEDGPRFLALSDAYDLELRKLLFKKWKELKIQRPLHEGTYTFVSGPTF
                     ETRAESKMIRMLGGDAVGMSTVPEVIVARHCGWRVLALSLITNTCVVDSPASALDESP
                     VPLEKGKATHAEVLENGKIASNDVQNLIAAVMGEL"
     gene            <562008..>563390
                     /gene="CLB4"
                     /locus_tag="YLR210W"
                     /db_xref="GeneID:850907"
     mRNA            <562008..>563390
                     /gene="CLB4"
                     /locus_tag="YLR210W"
                     /product="Clb4p"
                     /transcript_id="NM_001182097.1"
                     /db_xref="GI:296146747"
                     /db_xref="GeneID:850907"
     CDS             562008..563390
                     /gene="CLB4"
                     /locus_tag="YLR210W"
                     /note="B-type cyclin involved in cell cycle progression;
                     activates Cdc28p to promote the G2/M transition; may be
                     involved in DNA replication and spindle assembly;
                     accumulates during S phase and G2, then targeted for
                     ubiquitin-mediated degradation; CLB4 has a paralog, CLB3,
                     that arose from the whole genome duplication"
                     /codon_start=1
                     /product="Clb4p"
                     /protein_id="NP_013311.1"
                     /db_xref="GI:6323239"
                     /db_xref="SGD:S000004200"
                     /db_xref="GeneID:850907"
                     /translation="MMLEGYTVQPPQSTLIGDIEIQDENANQEVKNVLYQGVQKGIKR
                     LEKRQRRVALGDVTSQKANKIHNAIHNKFHQTKNNFEIENIRSSALVKEQQRDVRHED
                     SDYFLIDSSEGSSTDDEQVNEDAIDDLLSRRVNDQQIQADEVYEDFDGEMQDVIEEDV
                     DSQIEPLSPINNDEIQTELDRAFEKYFRSVPNPLDDDTHDVVMVVEYASDIFYYLREL
                     EVKYRPNPYYMQNQVELTWPFRRTMIDWLVQLHFRFQLLPETLYLTINIVDRFLSKKT
                     VTLNRFQLVGVSALFIAAKFEEINCPTLDDLVYMLENTYTRDDIIRAEQYMIDTLEFE
                     IGWPGPMPFLRRISKADDYDFEPRTLAKYLLETTIVEPKLVAAAPSWLAAGAYFLSRT
                     ILGSNDWSLKHVFYSGYTSSQIIPLASLILENCKNASRRHHSIWKKYFDQKHYRCSQI
                     VEEWIVSTEA"
     gene            complement(<563792..>564531)
                     /gene="ATG38"
                     /locus_tag="YLR211C"
                     /db_xref="GeneID:850908"
     mRNA            complement(join(<563792..564454,564514..>564531))
                     /gene="ATG38"
                     /locus_tag="YLR211C"
                     /product="Atg38p"
                     /transcript_id="NM_001182098.1"
                     /db_xref="GI:296146748"
                     /db_xref="GeneID:850908"
     CDS             complement(join(563792..564454,564514..564531))
                     /gene="ATG38"
                     /locus_tag="YLR211C"
                     /note="Homodimeric subunit of autophagy-specific
                     PtdIns-3-kinase complex I; required for the integrity of
                     the active PtdIns-3-kinase complex I by maintaining an
                     association between Vps15p-Vps34p and Atg14p-Vps30p
                     subcomplexes; localizes to the pre-autophagosomal
                     structure (PAS) in an Atg14p-dependent manner; ATG38 is
                     non-essential but is required for macroautophagy"
                     /codon_start=1
                     /product="Atg38p"
                     /protein_id="NP_013312.2"
                     /db_xref="GI:9755338"
                     /db_xref="SGD:S000004201"
                     /db_xref="GeneID:850908"
                     /translation="MSTLAEVYTIIEDAEQECRKGDFTNAKAKYQEAIEVLGPQNENL
                     SQNKLSSDVTQAIDLLKQDITAKIQELELLIEKQSSEENNIGMVNNNMLIGSVILNNK
                     SPINGISNARNWDNPAYQDTLSPINDPLLMSILNRLQFNLNNDIQLKTEGGKNSKNSE
                     MKINLRLEQFKKELVLYEQKKFKEYGMKIDEITKENKKLANEIGRLRERWDSLVESAK
                     QRRDKQKN"
     gene            complement(<564860..>566281)
                     /gene="TUB4"
                     /locus_tag="YLR212C"
                     /db_xref="GeneID:850909"
     mRNA            complement(<564860..>566281)
                     /gene="TUB4"
                     /locus_tag="YLR212C"
                     /product="Tub4p"
                     /transcript_id="NM_001182099.1"
                     /db_xref="GI:296146749"
                     /db_xref="GeneID:850909"
     CDS             complement(564860..566281)
                     /gene="TUB4"
                     /locus_tag="YLR212C"
                     /note="Gamma-tubulin; involved in nucleating microtubules
                     from both the cytoplasmic and nuclear faces of the spindle
                     pole body; protein abundance increases in response to DNA
                     replication stress"
                     /codon_start=1
                     /product="Tub4p"
                     /protein_id="NP_013313.1"
                     /db_xref="GI:6323241"
                     /db_xref="SGD:S000004202"
                     /db_xref="GeneID:850909"
                     /translation="MGGEIITLQAGQCGNHVGKFLWSQLAKEHAIGTDGLSQLPDSST
                     ERDDDTKPFFRENSRNKFTPRAIMMDSEPSVIADVENTFRGFFDPRNTWVASDGASAG
                     NSWANGYDIGTRNQDDILNKIDKEIDSTDNFEGFQLLHSVAGGTGSGLGSNLLEALCD
                     RYPKKILTTYSVFPARSSEVVVQSYNTILALRRLIEDSDATVVFDNASLLNISGKVFR
                     NPNIDLQHTNQLISTIISSVTNSIRFPSYMYSSMSSIYSTLIPSPELHFLSPSFTPFT
                     SDYIHDDIAHKGHSSYDVMLDLLDPSNSLVSTAMNNPTYFNVYNTIIGNVEPRQISRA
                     MTKLQQRIKFPSWSSSAMHVNIGRRSPYLPLQPNENEVSGMMLSNMSTVVNVFENACN
                     TFDKVFAKGAFLNNYNVGDLFQSMQNVQDEFAESREVVQSLMEDYVAAEQDSYLDDVL
                     VDDENMVGELEEDLDADGDHKLV"
     gene            complement(<566654..>567922)
                     /gene="CRR1"
                     /locus_tag="YLR213C"
                     /db_xref="GeneID:850910"
     mRNA            complement(<566654..>567922)
                     /gene="CRR1"
                     /locus_tag="YLR213C"
                     /product="Crr1p"
                     /transcript_id="NM_001182100.1"
                     /db_xref="GI:296146750"
                     /db_xref="GeneID:850910"
     CDS             complement(566654..567922)
                     /gene="CRR1"
                     /locus_tag="YLR213C"
                     /EC_number="3.2.-.-"
                     /note="Putative glycoside hydrolase of the spore wall
                     envelope; required for normal spore wall assembly,
                     possibly for cross-linking between the glucan and chitosan
                     layers; expressed during sporulation"
                     /codon_start=1
                     /product="Crr1p"
                     /protein_id="NP_013314.1"
                     /db_xref="GI:6323242"
                     /db_xref="SGD:S000004203"
                     /db_xref="GeneID:850910"
                     /translation="MRISILQLVPVVGYIGFALGELYKPKNSISCSPNNPCPAEWPCC
                     SPYNECGAGPICVGGCNVRSSFDEESCAPIPALVASQKLEFVSTPKVPKFIVNYQPKP
                     PIREGNGPNKANTKVGVVEGELNSKRIIHYAKFLVTPDSKEAEKMLEDFDFTHSGYTS
                     IEASSGNIVLAMPKKTTGSLITSTRSFLYGKASVRMKTARSRGVVTAFDLTSAIGDEI
                     DFEWLGGDLMTAQSNYYSQGHLDYTRMQRFPVGADTWATYHTYEIDWDPDRIIWYVDG
                     KIARTVLKKDTWDPISKEYRYPQTPMRLEIAVWPGGSETNGPGTINWAGGLIDWENSP
                     DIIEKGQFTAHVEQITVTPYQNKFTEQVQFCIKAKKKAPTFSQKDLSRVVVSYNRQDR
                     LNHHDEGSLKWDCFVTPKINDWLSSWKRSK"
     gene            <568567..>570627
                     /gene="FRE1"
                     /locus_tag="YLR214W"
                     /db_xref="GeneID:850911"
     mRNA            <568567..>570627
                     /gene="FRE1"
                     /locus_tag="YLR214W"
                     /product="Fre1p"
                     /transcript_id="NM_001182101.1"
                     /db_xref="GI:296146751"
                     /db_xref="GeneID:850911"
     CDS             568567..570627
                     /gene="FRE1"
                     /locus_tag="YLR214W"
                     /EC_number="1.16.1.9"
                     /note="Ferric reductase and cupric reductase; reduces
                     siderophore-bound iron and oxidized copper prior to uptake
                     by transporters; expression induced by low copper and iron
                     levels"
                     /codon_start=1
                     /product="Fre1p"
                     /protein_id="NP_013315.1"
                     /db_xref="GI:6323243"
                     /db_xref="SGD:S000004204"
                     /db_xref="GeneID:850911"
                     /translation="MVRTRVLFCLFISFFATVQSSATLISTSCISQAALYQFGCSSKS
                     KSCYCKNINWLGSVTACAYENSKSNKTLDSALMKLASQCSSIKVYTLEDMKNIYLNAS
                     NYLRAPEKSDKKTVVSQPLMANETAYHYYYEENYGIHLNLMRSQWCAWGLVFFWVAVL
                     TAATILNILKRVFGKNIMANSVKKSLIYPSVYKDYNERTFYLWKRLPFNFTTRGKGLV
                     VLIFVILTILSLSFGHNIKLPHPYDRPRWRRSMAFVSRRADLMAIALFPVVYLFGIRN
                     NPFIPITGLSFSTFNFYHKWSAYVCFMLAVVHSIVMTASGVKRGVFQSLVRKFYFRWG
                     IVATILMSIIIFQSEKVFRNRGYEIFLLIHKAMNIMFIIAMYYHCHTLGWMGWIWSMA
                     GILCFDRFCRIVRIIMNGGLKTATLSTTDDSNVIKISVKKPKFFKYQVGAFAYMYFLS
                     PKSAWFYSFQSHPFTVLSERHRDPNNPDQLTMYVKANKGITRVLLSKVLSAPNHTVDC
                     KIFLEGPYGVTVPHIAKLKRNLVGVAAGLGVAAIYPHFVECLRLPSTDQLQHKFYWIV
                     NDLSHLKWFENELQWLKEKSCEVSVIYTGSSVEDTNSDESTKGFDDKEESEITVECLN
                     KRPDLKELVRSEIKLSELENNNITFYSCGPATFNDDFRNAVVQGIDSSLKIDVELEEE
                     SFTW"
     gene            complement(<570776..>571858)
                     /gene="CDC123"
                     /locus_tag="YLR215C"
                     /db_xref="GeneID:850912"
     mRNA            complement(<570776..>571858)
                     /gene="CDC123"
                     /locus_tag="YLR215C"
                     /product="Cdc123p"
                     /transcript_id="NM_001182102.1"
                     /db_xref="GI:296146752"
                     /db_xref="GeneID:850912"
     CDS             complement(570776..571858)
                     /gene="CDC123"
                     /locus_tag="YLR215C"
                     /note="Protein involved in nutritional control of the cell
                     cycle; regulates abundance of the translation initiation
                     factor eIF2; ortholog of human D123 protein"
                     /codon_start=1
                     /product="Cdc123p"
                     /protein_id="NP_013316.1"
                     /db_xref="GI:6323244"
                     /db_xref="SGD:S000004205"
                     /db_xref="GeneID:850912"
                     /translation="MSSQEYTTFIDIPVTRAQVEHCSYSFWSSLYPKYVPKSIVLKSL
                     PKKFIQYLEQDGIKLPQEENSRSVYTEEIIRNEDNDYSDWEDDEDTATEFVQEVEPLI
                     DFPELHQKLKDALNELGAVAPKLNWSAPRDATWILPNNTMKCNEVNELYLLLNASNYI
                     MHDLQRAFKGCVDGDDIKGLKFDLVLRQWCDMNPALEFRVFVKNAHIVGATQRDLNYY
                     DYLDELSDTFKDLIDEIVHDVVLPKFPDKSFVLDVYIPRPFNKIFIVDINPFARKTDS
                     LLFSWNEIAAIAPPKNDVEDYELRLVTRHNTGRFASKEHSENHVPQDLVEASLNPEAI
                     RELTQKWKELLSQQAKEESSDSENET"
     gene            complement(<572096..>573211)
                     /gene="CPR6"
                     /locus_tag="YLR216C"
                     /gene_synonym="CYP40"
                     /db_xref="GeneID:850914"
     mRNA            complement(<572096..>573211)
                     /gene="CPR6"
                     /locus_tag="YLR216C"
                     /gene_synonym="CYP40"
                     /product="peptidylprolyl isomerase CPR6"
                     /transcript_id="NM_001182103.1"
                     /db_xref="GI:296146753"
                     /db_xref="GeneID:850914"
     CDS             complement(572096..573211)
                     /gene="CPR6"
                     /locus_tag="YLR216C"
                     /gene_synonym="CYP40"
                     /EC_number="5.2.1.8"
                     /note="Peptidyl-prolyl cis-trans isomerase (cyclophilin);
                     catalyzes the cis-trans isomerization of peptide bonds
                     N-terminal to proline residues; plays a role in
                     determining prion variants; binds to Hsp82p and
                     contributes to chaperone activity; protein abundance
                     increases in response to DNA replication stress"
                     /codon_start=1
                     /product="peptidylprolyl isomerase CPR6"
                     /protein_id="NP_013317.1"
                     /db_xref="GI:6323246"
                     /db_xref="SGD:S000004206"
                     /db_xref="GeneID:850914"
                     /translation="MTRPKTFFDISIGGKPQGRIVFELYNDIVPKTAENFLKLCEGNA
                     GMAKTKPDVPLSYKGSIFHRVIKDFMCQFGDFTNFNGTGGESIYDEKFEDENFTVKHD
                     KPFLLSMANAGPNTNGSQAFITCVPTPHLDGKHVVFGEVIQGKRIVRLIENQQCDQEN
                     NKPLRDVKIDDCGVLPDDYQVPENAEATPTDEYGDNYEDVLKQDEKVDLKNFDTVLKA
                     IETVKNIGTEQFKKQNYSVALEKYVKCDKFLKEYFPEDLEKEQIEKINQLKVSIPLNI
                     AICALKLKDYKQVLVASSEVLYAEAADEKAKAKALYRRGLAYYHVNDTDMALNDLEMA
                     TTFQPNDAAILKAIHNTKLKRKQQNEKAKKSLSKMFS"
     gene            complement(<573466..>573918)
                     /gene="COA4"
                     /locus_tag="YLR218C"
                     /gene_synonym="CMC3"
                     /db_xref="GeneID:850915"
     mRNA            complement(<573466..>573918)
                     /gene="COA4"
                     /locus_tag="YLR218C"
                     /gene_synonym="CMC3"
                     /product="Coa4p"
                     /transcript_id="NM_001182105.1"
                     /db_xref="GI:296146754"
                     /db_xref="GeneID:850915"
     CDS             complement(573466..573918)
                     /gene="COA4"
                     /locus_tag="YLR218C"
                     /gene_synonym="CMC3"
                     /note="Twin Cx(9)C protein involved in cytochrome c
                     oxidase organization; organization includes assembly or
                     stability; localizes to the mitochondrial intermembrane
                     space via the Mia40p-Erv1p system; interacts genetically
                     with CYC1 and with cytochrome c oxidase assembly factors"
                     /codon_start=1
                     /product="Coa4p"
                     /protein_id="NP_013319.1"
                     /db_xref="GI:6323247"
                     /db_xref="SGD:S000004208"
                     /db_xref="GeneID:850915"
                     /translation="MLLFSSFFSHNKCPKQKKGPQPLKVVKGTSKSCAKQGKIKGKEK
                     LWQAKTGRLVMSETGETSEYYKQALEEYKEVQEDEDPDVWDTRISKTGCYVENLALQL
                     CHAETGDWRQCFNEMALFRKCWEKNGNRERVSTVDVDGTTSKDSEKKK"
     gene            <574151..>576337
                     /gene="MSC3"
                     /locus_tag="YLR219W"
                     /db_xref="GeneID:850916"
     mRNA            <574151..>576337
                     /gene="MSC3"
                     /locus_tag="YLR219W"
                     /product="Msc3p"
                     /transcript_id="NM_001182106.1"
                     /db_xref="GI:296146755"
                     /db_xref="GeneID:850916"
     CDS             574151..576337
                     /gene="MSC3"
                     /locus_tag="YLR219W"
                     /note="hypothetical protein; green fluorescent protein
                     (GFP)-fusion protein localizes to the cell periphery; msc3
                     mutants are defective in directing meiotic recombination
                     events to homologous chromatids; potential Cdc28p
                     substrate; protein abundance increases in response to DNA
                     replication stress"
                     /codon_start=1
                     /product="Msc3p"
                     /protein_id="NP_013320.1"
                     /db_xref="GI:6323248"
                     /db_xref="SGD:S000004209"
                     /db_xref="GeneID:850916"
                     /translation="MVFGFTKRDRRVPDLSRYDYYYQNHEDYNKSPQLSAAAASAASA
                     ASPDRTNYSRSHSLVSHAPSIPRQRSSVKSPGRRLSTSSAAPPTSRAAAKQYSQKTYS
                     LRSQRSGEYHLHPPGYTTNGSRMNSMTSGANVRRNYGKNKSTAGNNNDSRANSITVKT
                     TQVTDPSGRTQSITKKTIRKINGYEYVETTTTTKNLVPLGDSQRHFDEFSENYMLQDD
                     DILEEQASDNIHDIIEENETDNEKPYSPVSESHLQDDSELNVEKPDFPLGSYFHHKYS
                     TDVMPLEEESSLSNFSDALDYIPPTHQTSSKYIHNKRKQASTTRRKKRPPAVKNAEAE
                     AKKPLTEAEMYLKALEVAKRNVYHTDAASDNASAPLGSNKSRKSRMGQKMTLRSSSDS
                     PTATANLVKSNVEVQPKRFTSSFFSRNTKSAPHEVHNHSVSTHFKSNKAVDPVPEPKS
                     ANTGLTDKEMYDQALKIAQARYYNSHGIQPEAVDNSTTAAKPRQVGVSHLGSTGSIPP
                     NEQHYLGDSEIPVQSEVHEYEPIPLQKTKTTGSSKNKFKTMFDKVLQFSQENYGYQHK
                     KEQGEQTPVTRNAEESFPAASISEGVTTAKPSSNEGVMTNPVVTDSPSPLQQQIDSTT
                     ASSNGQSQGNVPTSAVASTTRTRSPELQDNLKSSSSLLQDQTPQRQEDATDPTTSSTN
                     ELSAAEPTMVTSTHATKTIQAQTQDPPTKHKKSSFFTKLFKKKSSR"
     gene            <576825..>577793
                     /gene="CCC1"
                     /locus_tag="YLR220W"
                     /db_xref="GeneID:850917"
     mRNA            <576825..>577793
                     /gene="CCC1"
                     /locus_tag="YLR220W"
                     /product="Ccc1p"
                     /transcript_id="NM_001182107.1"
                     /db_xref="GI:296146756"
                     /db_xref="GeneID:850917"
     CDS             576825..577793
                     /gene="CCC1"
                     /locus_tag="YLR220W"
                     /note="Putative vacuolar Fe2+/Mn2+ transporter; suppresses
                     respiratory deficit of yfh1 mutants, which lack the
                     ortholog of mammalian frataxin, by preventing
                     mitochondrial iron accumulation; relative distribution to
                     the vacuole decreases upon DNA replication stress"
                     /codon_start=1
                     /product="Ccc1p"
                     /protein_id="NP_013321.1"
                     /db_xref="GI:6323249"
                     /db_xref="SGD:S000004210"
                     /db_xref="GeneID:850917"
                     /translation="MSIVALKNAVVTLIQKAKGSGGTSELGGSESTPLLRGSNSNSSR
                     HDNLSSSSSDIIYGRNSAQDLENSPMSVGKDNRNGDNGSDNEKANLGFFQSVDPRVIS
                     DLIIGLSDGLTVPFALTAGLSSLGDAKLVITGGFAELISGAISMGLGGYLGAKSESDY
                     YHAEVKKEKRKFYDNSNLINREIEDILLEINPNFSDETIVSFIKDLQRTPELMVDFII
                     RYGRGLDEPAENRELISAVTIGGGYLLGGLVPLVPYFFVSDVGTGLIYSIIVMVVTLF
                     WFGYVKTKLSMGSGSSTSKKVTEGVEMVVVGGVAAGAAWFFVKLLG"
     gene            complement(<578362..>579024)
                     /gene="RSA3"
                     /locus_tag="YLR221C"
                     /db_xref="GeneID:850918"
     mRNA            complement(<578362..>579024)
                     /gene="RSA3"
                     /locus_tag="YLR221C"
                     /product="Rsa3p"
                     /transcript_id="NM_001182108.1"
                     /db_xref="GI:296146757"
                     /db_xref="GeneID:850918"
     CDS             complement(578362..579024)
                     /gene="RSA3"
                     /locus_tag="YLR221C"
                     /note="Protein with a likely role in ribosomal maturation;
                     required for accumulation of wild-type levels of large
                     (60S) ribosomal subunits; binds to the helicase Dbp6p in
                     pre-60S ribosomal particles in the nucleolus"
                     /codon_start=1
                     /product="Rsa3p"
                     /protein_id="NP_013322.1"
                     /db_xref="GI:6323250"
                     /db_xref="SGD:S000004211"
                     /db_xref="GeneID:850918"
                     /translation="MSAGDISAINIKSVKKNRRRKKRRTADVSSSDSSSSDPSSESEK
                     EEIQNGAIEEHVGENGKSDHVFSKGNDEDKQEDIAIEVSDVELTDEESKDLKLNSKEV
                     IDDLTKISLSKIPEPTKSQNKEGFMNASKIAENIKLAREEYNELAENFVPKGKDKTKL
                     REEYLNLLFENYGDDINRLRAAPDFTNKSLSILADALQEGIGMFDIGELELVLKNKEM
                     EN"
     gene            complement(<579318..>581771)
                     /gene="UTP13"
                     /locus_tag="YLR222C"
                     /db_xref="GeneID:850919"
     mRNA            complement(<579318..>581771)
                     /gene="UTP13"
                     /locus_tag="YLR222C"
                     /product="Utp13p"
                     /transcript_id="NM_001182109.1"
                     /db_xref="GI:296146758"
                     /db_xref="GeneID:850919"
     CDS             complement(579318..581771)
                     /gene="UTP13"
                     /locus_tag="YLR222C"
                     /note="Nucleolar protein; component of the small subunit
                     (SSU) processome containing the U3 snoRNA that is involved
                     in processing of pre-18S rRNA"
                     /codon_start=1
                     /product="Utp13p"
                     /protein_id="NP_013323.1"
                     /db_xref="GI:6323251"
                     /db_xref="SGD:S000004212"
                     /db_xref="GeneID:850919"
                     /translation="MDLKTSYKGISLNPIYAGSSAVATVSENGKILATPVLDEINIID
                     LTPGSRKILHKISNEDEQEITALKLTPDGQYLTYVSQAQLLKIFHLKTGKVVRSMKIS
                     SPSYILDADSTSTLLAVGGTDGSIIVVDIENGYITHSFKGHGGTISSLKFYGQLNSKI
                     WLLASGDTNGMVKVWDLVKRKCLHTLQEHTSAVRGLDIIEVPDNDEPSLNLLSGGRDD
                     IINLWDFNMKKKCKLLKTLPVNQQVESCGFLKDGDGKRIIYTAGGDAIFQLIDSESGS
                     VLKRTNKPIEELFIIGVLPILSNSQMFLVLSDQTLQLINVEEDLKNDEDTIQVTSSIA
                     GNHGIIADMRYVGPELNKLALATNSPSLRIIPVPDLSGPEASLPLDVEIYEGHEDLLN
                     SLDATEDGLWIATASKDNTAIVWRYNENSCKFDIYAKYIGHSAAVTAVGLPNIVSKGY
                     PEFLLTASNDLTIKKWIIPKPTASMDVQIIKVSEYTRHAHEKDINALSVSPNDSIFAT
                     ASYDKTCKIWNLENGELEATLANHKRGLWDVSFCQYDKLLATSSGDKTVKIWSLDTFS
                     VMKTLEGHTNAVQRCSFINKQKQLISCGADGLIKIWDCSSGECLKTLDGHNNRLWALS
                     TMNDGDMIVSADADGVFQFWKDCTEQEIEEEQEKAKLQVEQEQSLQNYMSKGDWTNAF
                     LLAMTLDHPMRLFNVLKRALGESRSRQDTEEGKIEVIFNEELDQAISILNDEQLILLM
                     KRCRDWNTNAKTHTIAQRTIRCILMHHNIAKLSEIPGMVKIVDAIIPYTQRHFTRVDN
                     LVEQSYILDYALVEMDKLF"
     gene            complement(<582233..>585490)
                     /gene="IFH1"
                     /locus_tag="YLR223C"
                     /db_xref="GeneID:850920"
     mRNA            complement(<582233..>585490)
                     /gene="IFH1"
                     /locus_tag="YLR223C"
                     /product="Ifh1p"
                     /transcript_id="NM_001182110.1"
                     /db_xref="GI:296146759"
                     /db_xref="GeneID:850920"
     CDS             complement(582233..585490)
                     /gene="IFH1"
                     /locus_tag="YLR223C"
                     /note="Coactivator, regulates transcription of ribosomal
                     protein (RP) genes; recruited to RP gene promoters during
                     optimal growth conditions via Fhl1p; subunit of CURI, a
                     complex that coordinates RP production and pre-rRNA
                     processing; regulated by acetylation and phosphorylation
                     at different growth states via TORC1 signaling; IFH1 has a
                     paralog, CRF1, that arose from the whole genome
                     duplication"
                     /codon_start=1
                     /product="Ifh1p"
                     /protein_id="NP_013324.1"
                     /db_xref="GI:6323252"
                     /db_xref="SGD:S000004213"
                     /db_xref="GeneID:850920"
                     /translation="MAGKKSPRKSTINHSTHSGKLPANIKRLIKKGESDTKSRQSPPT
                     LSTTRPRRFSLIYSSESSLSDVSDSDKNKSTNPHKIKRKAKNISNNSQGKKSKLIQRQ
                     IDNDDEGTESSDYQAVTDGEESENEEEESEEEEEDDDEDDDDDDDDGSDSDSDSETSS
                     DDENIDFVKLTAQRKKRAMKALSAMNTNSNTLYSSRENSNKNKSVKLSPKKENEEEQK
                     EEKEKEKEEQQKQQESNKKEVNGSGTTTTQQALSFKFKKEDDGISFGNGNEGYNEDIG
                     EEVLDLKNKENNGNEEDKLDSKVMLGNNDELRFPNISESDESEYDIDQDAYFDVINNE
                     DSHGEIGTDLETGEDDLPILEEEEQNIVSELQNDDELSFDGSIHEEGSDPVEDAENKF
                     LQNEYNQENGYDEEDDEEDEIMSDFDMPFYEDPKFANLYYYGDGSEPKLSLSTSLPLM
                     LNDEKLSKLKKKEAKKREQEERKQRRKLYKKTQKPSTRTTSNVDNDEYIFNVFFQSDD
                     ENSGHKSKKGRHKSGKSHIEHKNKGSNLIKSNDDLEPSTHSTVLNSGKYDSSDDEYDN
                     ILLDVAHMPSDDECSESETSHDADTDEELRALDSDSLDIGTELDDDYEDDDDDSSVTN
                     VFIDIDDLDPDSFYFHYDSDGSSSLISSNSDKENSDGSKDCKHDLLETVVYVDDESTD
                     EDDNLPPPSSRSKNIGSKAKEIVSSNVVGLRPPKLGTWETDNKPFSIIDGLSTKSLYA
                     LIQEHQQLREQHQRAQTPDVKREGSSNGNNGDELTLNELLNMSELEDDSPSHTDDMEN
                     NYNDAINSKSTNGHAADWYEVPKVPLSAFRNKGINAYEEDEYMIPANSNRKVPIGYIG
                     NERTRKKIDKMKELQRKKTEKKRQLKKKKKLLKIRKQRQKAIKEQETMNLQLGINGHE
                     IIGNNNSHSDINTGTDFTTNENTPMNELPSHAPEDASLIPHNSDLAVDSNTRKNSTKS
                     VGLDEIHEILGKDENDLLSVGDINGYDAQEGHVIEDTDADILASLTAPVQFDNTLSHE
                     NSNSMWRRRQSMVEAAAENLRFTKNGLFSESALADIEGIMGNDVNHSFEFNDVLQ"
     gene            <586464..>587573
                     /locus_tag="YLR224W"
                     /db_xref="GeneID:850921"
     mRNA            <586464..>587573
                     /locus_tag="YLR224W"
                     /product="hypothetical protein"
                     /transcript_id="NM_001182111.1"
                     /db_xref="GI:296146760"
                     /db_xref="GeneID:850921"
     CDS             586464..587573
                     /locus_tag="YLR224W"
                     /note="F-box protein and component of SCF ubiquitin ligase
                     complexes; involved in ubiquitin-dependent protein
                     catabolism; readily monoubiquitinated in vitro by SCF-Ubc4
                     complexes; YLR224W is not an essential gene"
                     /codon_start=1
                     /product="hypothetical protein"
                     /protein_id="NP_013325.1"
                     /db_xref="GI:6323253"
                     /db_xref="SGD:S000004214"
                     /db_xref="GeneID:850921"
                     /translation="MNQSDSSLMDLPLEIHLSLLEYVPNELRAVNKYFYVLHNHSYKE
                     KSLAWIAEDNYIWAVVKHSLCLYVKSLDPLRQHAREIIQETKEPGFNVPLCMTKYIAD
                     SWYIVYNALQYPGKIINMGWDKYTKSQDSNGSDSTSNFNSRPKERTLMQSLTALPVNF
                     WSRRKDEPTPVNVWFYVKNAHVARYIPKIITEIGICNYGPKQIVASAGYINELITSEG
                     IYCVNLGHLPRLYDEQIFEGTGTTHLPLELKAIDRTDSDVCINGDLVLLGYDFIPYQI
                     SKPWLLFRIEPVNSIEAIFNYSECSFSYQFAWSLACLQSEEKISFPRDTIIGHGLPYK
                     PSKLIRIFVYKHPEQKQDLGQEIALPNWNTPYLRR"
     gene            complement(<587695..>588918)
                     /locus_tag="YLR225C"
                     /db_xref="GeneID:850922"
     mRNA            complement(<587695..>588918)
                     /locus_tag="YLR225C"
                     /product="hypothetical protein"
                     /transcript_id="NM_001182112.1"
                     /db_xref="GI:296146761"
                     /db_xref="GeneID:850922"
     CDS             complement(587695..588918)
                     /locus_tag="YLR225C"
                     /note="hypothetical protein; green fluorescent protein
                     (GFP)-fusion protein localizes to the cytoplasm; not an
                     essential gene; YLR225C has a paralog, YDR222W, that arose
                     from the whole genome duplication"
                     /codon_start=1
                     /product="hypothetical protein"
                     /protein_id="NP_013326.1"
                     /db_xref="GI:6323254"
                     /db_xref="SGD:S000004215"
                     /db_xref="GeneID:850922"
                     /translation="MAVAIKKEKTKFAPVKEVLSEKDHANYTKFQDTSKLEWFCRTSN
                     HKKFKSHSLLKAVRNPTETRIETQTLYFTDLTNGKCGLIQLLYSSVMGGIYKGFQLNF
                     KIFKASSEENSEEDIDIWESFKIDNIKDFDTLKVESDNVTFHFVPLENSSSSGFAQLL
                     IKIDIPKGSTSCLLKDLKVDITVNLQEGFIINPDGSNYYLDKSISLEELAKRDSSSTS
                     RKMIRHVFVPRGFCNGTISYKKNDKPVKLDLKDTPMLYLDAVQGLIPNKAASKWNFLC
                     FNGEKRSMMCIEFTTTKEYGSTTVTIWAVSDKDKILEVGSSVNDHAVKFPSTKEDKQN
                     GWKYPTSISFPRGFEESNLRLVNRYDIMSELPAFIRSIAENLANMKPFIYQFCQKSKF
                     DDDEGVSIIESTFIN"
     gene            <589354..>590541
                     /gene="BUR2"
                     /locus_tag="YLR226W"
                     /gene_synonym="CST4"
                     /db_xref="GeneID:850923"
     mRNA            <589354..>590541
                     /gene="BUR2"
                     /locus_tag="YLR226W"
                     /gene_synonym="CST4"
                     /product="Bur2p"
                     /transcript_id="NM_001182113.1"
                     /db_xref="GI:296146762"
                     /db_xref="GeneID:850923"
     CDS             589354..590541
                     /gene="BUR2"
                     /locus_tag="YLR226W"
                     /gene_synonym="CST4"
                     /note="Cyclin for the Sgv1p (Bur1p) protein kinase; Sgv1p
                     and Bur2p comprise the CDK-cyclin BUR kinase complex which
                     is involved in transcriptional regulation through its
                     phosphorylation of the carboxy-terminal domain (CTD) of
                     the largest subunit of RNA polymerase II (Rpo21p); BUR
                     kinase is also involved in the recruitment of Spt6p to the
                     CTD at the onset of transcription"
                     /codon_start=1
                     /product="Bur2p"
                     /protein_id="NP_013327.1"
                     /db_xref="GI:6323255"
                     /db_xref="SGD:S000004216"
                     /db_xref="GeneID:850923"
                     /translation="MSATSSSGDVKKFQAVPKPTSNASPPPASSGFNARTLWPDLIET
                     PENQWVFECKDIIEKIGTNGPIAVEIKKNMEKCLMYFYTLKKKLNLFDHTYTASCILF
                     YRYWFIYGIPTAITECIHISQGILVTACKTMENNRPIEAYIKATCEFLMQNIPSLKSR
                     TNIDKLKWEFRDKLVTNEKKILCLFGFDLNISNPKELIEEVFSGYYRFNRDHNLPENF
                     KKAFPKILQESRNFMVQAVTQPVSLLCDGYTFIVLSLIYCGLEYKKLVDKDFRYPKNF
                     FKDRFPIEVTPENFANIFTDYKLLEENFFNLKSNKGAKLQIDSSMIDSVIDESGDVEN
                     EVSEISDPFNYELIKSGEVKEEFLNHIETRVKDLLDKAKQESMKRKAKDPIRTPDAKK
                     PKI"
     gene            complement(<590562..>592043)
                     /gene="ADY4"
                     /locus_tag="YLR227C"
                     /db_xref="GeneID:850924"
     mRNA            complement(<590562..>592043)
                     /gene="ADY4"
                     /locus_tag="YLR227C"
                     /product="Ady4p"
                     /transcript_id="NM_001182114.1"
                     /db_xref="GI:296146763"
                     /db_xref="GeneID:850924"
     CDS             complement(590562..592043)
                     /gene="ADY4"
                     /locus_tag="YLR227C"
                     /note="Structural component of the meiotic outer plaque;
                     outer plaque is a membrane-organizing center that
                     assembles on the cytoplasmic face of the spindle pole body
                     during meiosis II and triggers the formation of the
                     prospore membrane"
                     /codon_start=1
                     /product="Ady4p"
                     /protein_id="NP_013328.1"
                     /db_xref="GI:6323256"
                     /db_xref="SGD:S000004217"
                     /db_xref="GeneID:850924"
                     /translation="MNKDVDYQTFKKSLRKEFKKAVKTILNLQAYNGDLIRDFLALYI
                     PYHVVFYNLSIMKKGSPLRIQTNNLLKEALAKILNFNLAMGPKHIIKIMKKDKADPET
                     MNKLKLVLYIKLFQGVFGHVDKNYNLAFQSFRWCLQFIAYSKRTRLFASIADEQIGAF
                     YELCELFISMLCCHCFLIDLKENEALVGNNLKNFIKRQNPNYSHGFDLNEETKSLQWH
                     WSLDEVDVIEALYCVAFDAMDKITLKFSKVNENFVFSQFFQYCAEIEEMLAILRGKIW
                     ECECDVFGPRIGLLVDSNHMNETIQKNILSITFKLKNDPQIICCLNKILEGLLLSSGV
                     QFKVIQFFYVLKLYYMQDNEYTFEASSEMDKLTIECLCIIENIIDACDNPDEVTDYQL
                     PKVLLTAMEGKLLVAEKISEDNDCSESLDDYHPRTYQFRHPRIIIDKMKTKLKQKLRF
                     DSPKDPETDDHWIEYWKYCYQDNIGNLPDILSRIYQTFTDPSN"
     gene            complement(592519..592619)
                     /locus_tag="tL(UAG)L1"
                     /db_xref="GeneID:850925"
     tRNA            complement(join(592519..592562,592582..592619))
                     /locus_tag="tL(UAG)L1"
                     /product="tRNA-Leu"
                     /note="Leucine tRNA (tRNA-Leu), predicted by tRNAscan-SE
                     analysis"
                     /db_xref="SGD:S000006655"
                     /db_xref="GeneID:850925"
     LTR             complement(592706..593035)
                     /note="Ty1 LTR"
                     /db_xref="SGD:S000007070"
     mobile_element  593145..599062
                     /note="YLRWTy1-2; Ty1 element, LTR retrotransposon of the
                     Copia (Pseudoviridae) group; contains co-transcribed genes
                     TYA Gag and TYB Pol, encoding proteins involved in
                     structure and function of virus-like particles, flanked by
                     two direct repeats"
                     /mobile_element_type="retrotransposon:YLRWTy1-2"
                     /db_xref="SGD:S000007098"
     LTR             593145..593478
                     /note="Ty1 LTR"
                     /db_xref="SGD:S000007085"
     gene            <593438..>598706
                     /locus_tag="YLR227W-B"
                     /db_xref="GeneID:850927"
     mRNA            join(<593438..594742,594744..>598706)
                     /locus_tag="YLR227W-B"
                     /product="gag-pol fusion protein"
                     /transcript_id="NM_001184408.1"
                     /db_xref="GI:296146765"
                     /db_xref="GeneID:850927"
     CDS             join(593438..594742,594744..598706)
                     /locus_tag="YLR227W-B"
                     /EC_number="3.4.23.-"
                     /EC_number="3.1.26.4"
                     /EC_number="2.7.7.7"
                     /EC_number="2.7.7.49"
                     /ribosomal_slippage
                     /note="Retrotransposon TYA Gag and TYB Pol genes;
                     transcribed/translated as one unit; polyprotein is
                     processed to make a nucleocapsid-like protein (Gag),
                     reverse transcriptase (RT), protease (PR), and integrase
                     (IN); similar to retroviral genes"
                     /codon_start=1
                     /product="gag-pol fusion protein"
                     /protein_id="NP_058171.1"
                     /db_xref="GI:7839187"
                     /db_xref="SGD:S000007376"
                     /db_xref="GeneID:850927"
                     /translation="MESQQLSQHSHISHGSACASVTSKEVHTNQDPLDVSASKTEECE
                     KASTKANSQQTTTPASSAVPENPHHASPQPASVPPPQNGPYPQQCMMTQNQANPSGWS
                     FYGHPSMIPYTPYQMSPMYFPPGPQSQFPQYPSSVGTPLSTPSPESGNTFTDSSSADS
                     DMTSTKKYVRPPPMLTSPNDFPNWVKTYIKFLQNSNLGGIIPTVNGKPVRQITDDELT
                     FLYNTFQIFAPSQFLPTWVKDILSVDYTDIMKILSKSIEKMQSDTQEANDIVTLANLQ
                     YNGSTPADAFETKVTNIIDRLNNNGIHINNKVACQLIMRGLSGEYKFLRYTRHRHLNM
                     TVAELFLDIHAIYEEQQGSRNSKPNYRRNLSDEKNDSRSYTNTTKPKVIARNPQKTNN
                     SKSKTARAHNVSTSNNSPSTDNDSISKSTTEPIQLNNKHDLHLGQELTESTVNHTNHS
                     DDELPGHLLLDSGASRTLIRSAHHIHSASSNPDINVVDAQKRNIPINAIGDLQFHFQD
                     NTKTSIKVLHTPNIAYDLLSLNELAAVDITACFTKNVLERSDGTVLAPIVQYGDFYWV
                     SKRYLLPSNISVPTINNVHTSESTRKYPYPFIHRMLAHANAQTIRYSLKNNTITYFNE
                     SDVDWSSAIDYQCPDCLIGKSTKHRHIKGSRLKYQNSYEPFQYLHTDIFGPVHNLPKS
                     APSYFISFTDETTKFRWVYPLHDRREDSILDVFTTILAFIKNQFQASVLVIQMDRGSE
                     YTNRTLHKFLEKNGITPCYTTTADSRAHGVAERLNRTLLDDCRTQLQCSGLPNHLWFS
                     AIEFSTIVRNSLASPKSKKSASQHAGLAGLDISTLLPFGQPVIVNDHNPNSKIHPRGI
                     PGYALHPSRNSYGYIIYLPSLKKTVDTTNYVILQGKESRLDQFNYDALTFDEDLNRLT
                     ASYHSFIASNEIQESNDLNIESDHDFQSDIELHPEQPRNVLSKAVSPTDSTPPSTHTE
                     DSKPISEINLRAPREVDPNISESNILPSKKRSSTPQISNIESTGSGGMHKLNVPLLAP
                     MSQSNTHESSHASKSKDFRHSDSYSNNETNHTNVPISSTGGTNNKTVPQISDQETEKR
                     IIHRSPSIDASPPENNSSHNIVPIKTPTTVSEQNTEESIIADLPLPDPPPEPPTELSD
                     SFKELPPINSRQTNSSLGGIGDSNAYTTINSKKRSLEDNETEIKVSRDTWNTKNMRSL
                     EPPRSKKRIHLIAAAKAVKSIKPIRTTLRYDEAITYNKDIKEKEKYIEAYHKEVNQLL
                     KMNTWDTDKYYDRKEIDPKRVINSMFIFNKKRDGTHKARFVARGDIQHPDTYDTGMQS
                     NTVHHYALMTSLSLALDNNYYITQLDISSAYLYADIKEELYIRPPPHLGMNDKLIRLK
                     KSHYGLKQSGANWYETIKSYLIKQCGMEEVRGWSCVFKNSQVTICLFVDDMILFSKDL
                     NANKKIITTLKKQYDTKIINLGESDNEIQYDILGLEIKYQRGKYMKLGMENSLTEKIP
                     KLNVPLNPKGRKLSAPGQPGLYIDQDELEIDEDEYKEKVHEMQKLIGLASYVGYKFRF
                     DLLYYINTLAQHILFPSRQVLDMTYELIQFMWDTRDKQLIWHKNKPTEPDNKLVAISD
                     ASYGNQPYYKSQIGNIFLLNGKVIGGKSTKASLTCTSTTEAEIHAVSEAIPLLNNLSH
                     LVQELNKKPIIKGLLTDSRSTISIIKSTNEEKFRNRFFGTKAMRLRDEVSGNNLYVYY
                     IETKKNIADVMTKPLPIKTFKLLTNKWIH"
     gene            <593438..>594760
                     /locus_tag="YLR227W-A"
                     /db_xref="GeneID:850926"
     mRNA            <593438..>594760
                     /locus_tag="YLR227W-A"
                     /product="gag protein"
                     /transcript_id="NM_001184407.1"
                     /db_xref="GI:296146764"
                     /db_xref="GeneID:850926"
     CDS             593438..594760
                     /locus_tag="YLR227W-A"
                     /note="Retrotransposon TYA Gag gene co-transcribed with
                     TYB Pol; translated as TYA or TYA-TYB polyprotein; Gag is
                     a nucleocapsid protein that is the structural constituent
                     of virus-like particles (VLPs); similar to retroviral Gag"
                     /codon_start=1
                     /product="gag protein"
                     /protein_id="NP_058172.1"
                     /db_xref="GI:7839186"
                     /db_xref="SGD:S000007375"
                     /db_xref="GeneID:850926"
                     /translation="MESQQLSQHSHISHGSACASVTSKEVHTNQDPLDVSASKTEECE
                     KASTKANSQQTTTPASSAVPENPHHASPQPASVPPPQNGPYPQQCMMTQNQANPSGWS
                     FYGHPSMIPYTPYQMSPMYFPPGPQSQFPQYPSSVGTPLSTPSPESGNTFTDSSSADS
                     DMTSTKKYVRPPPMLTSPNDFPNWVKTYIKFLQNSNLGGIIPTVNGKPVRQITDDELT
                     FLYNTFQIFAPSQFLPTWVKDILSVDYTDIMKILSKSIEKMQSDTQEANDIVTLANLQ
                     YNGSTPADAFETKVTNIIDRLNNNGIHINNKVACQLIMRGLSGEYKFLRYTRHRHLNM
                     TVAELFLDIHAIYEEQQGSRNSKPNYRRNLSDEKNDSRSYTNTTKPKVIARNPQKTNN
                     SKSKTARAHNVSTSNNSPSTDNDSISKSTTEPIQLNNKHDLHLRPGTY"
     LTR             598729..599062
                     /note="Ty1 LTR"
                     /db_xref="SGD:S000007086"
     LTR             599268..599544
                     /note="Ty1 LTR"
                     /db_xref="SGD:S000007087"
     LTR             complement(599570..599844)
                     /note="Ty4 LTR"
                     /db_xref="SGD:S000007080"
     gene            complement(<600019..>602463)
                     /gene="ECM22"
                     /locus_tag="YLR228C"
                     /db_xref="GeneID:850928"
     mRNA            complement(<600019..>602463)
                     /gene="ECM22"
                     /locus_tag="YLR228C"
                     /product="Ecm22p"
                     /transcript_id="NM_001182115.1"
                     /db_xref="GI:296146766"
                     /db_xref="GeneID:850928"
     CDS             complement(600019..602463)
                     /gene="ECM22"
                     /locus_tag="YLR228C"
                     /note="Sterol regulatory element binding protein;
                     regulates transcription of sterol biosynthetic genes;
                     contains Zn[2]-Cys[6] binuclear cluster; relocates from
                     intracellular membranes to perinuclear foci on sterol
                     depletion; ECM22 has a paralog, UPC2, that arose from the
                     whole genome duplication"
                     /codon_start=1
                     /product="Ecm22p"
                     /protein_id="NP_013329.1"
                     /db_xref="GI:6323257"
                     /db_xref="SGD:S000004218"
                     /db_xref="GeneID:850928"
                     /translation="MTSDDGNAGQEREKDAELIEVGGKKVSKTSTGKRKFHNKSKTGC
                     DNCKRRRVKCDEGKPFCKKCTNMKLDCVYSPIQPRRRKDSSSSKFASAVHDRVGKKNL
                     SDNAIMLQQQQQQLHHQQEQQFRQQQQVQLQQQLLPHVGTDEQSNSPNSVPPSVSNNM
                     ENLLLPHLLASLVNNTSNSTNSSANGAEAHNNITQTAPSSMINNNHPNMALPGNSPLS
                     IPITPSFQSTAMNLSSSLNGLLSPGRLNSVTNGLQQPQLQQQNQQIPQQQGTQSPFSN
                     IPFDQLAQLNKMGLNFNMKSFNTLFPYGAANGMASEFQELFGLGKFATSNNRAIKVST
                     AEEALANMQQEQEDKNKQFTKNPLDNTKTDAVNSGNNPLNGNENKVTASDILSHNKNL
                     IIDNTGLTISPPHTLSKPSIDQNIASPSTGVSNVTSTKSLLSIPDNRTALGNSPTLKT
                     SPMGDLLSNSEALSPRSSNSHTQQQSSPHSNASSASRLVPELVGLSRKSNLNLIDLKL
                     FHHYCTDVWHTITEAGISGPEVWSTYIPDLAFHFPFLMHTILAFSATHLSRTEAGLDN
                     YVSSHRLEALRLLREAVLEISDDNTDALVASALILILDSLANASSSSPTAWIFHVKGA
                     VTILTAVWPLSETSKFYNLISVDLSDLGEAVINQSNHNNDNDNSNNGDGNNNNTISEL
                     VCFDESIADLYPVEIDSPYLITLAYLDKLHREKNQLDFMLRVFSFPALLDRTFLALLM
                     TGDLGAMRIMRSYYTLLRGYTTEIKDKVWFLDSVSQVLPQDVDEYSGGGGMHMMLDFL
                     GGGLPSMTTTNFSAFM"
     rep_origin      602939..603155
                     /note="ARS1218;
                     Autonomously Replicating Sequence"
                     /db_xref="SGD:S000118477"
     gene            complement(<604212..>604787)
                     /gene="CDC42"
                     /locus_tag="YLR229C"
                     /db_xref="GeneID:850930"
     mRNA            complement(<604212..>604787)
                     /gene="CDC42"
                     /locus_tag="YLR229C"
                     /product="Rho family GTPase CDC42"
                     /transcript_id="NM_001182116.1"
                     /db_xref="GI:296146767"
                     /db_xref="GeneID:850930"
     CDS             complement(604212..604787)
                     /gene="CDC42"
                     /locus_tag="YLR229C"
                     /note="Small rho-like GTPase; essential for establishment
                     and maintenance of cell polarity; plays a role late in
                     cell fusion via activation of key cell fusion regulator
                     Fus2p; mutants have defects in the organization of actin
                     and septins"
                     /codon_start=1
                     /product="Rho family GTPase CDC42"
                     /protein_id="NP_013330.1"
                     /db_xref="GI:6323259"
                     /db_xref="SGD:S000004219"
                     /db_xref="GeneID:850930"
                     /translation="MQTLKCVVVGDGAVGKTCLLISYTTNQFPADYVPTVFDNYAVTV
                     MIGDEPYTLGLFDTAGQEDYDRLRPLSYPSTDVFLVCFSVISPPSFENVKEKWFPEVH
                     HHCPGVPCLVVGTQIDLRDDKVIIEKLQRQRLRPITSEQGSRLARELKAVKYVECSAL
                     TQRGLKNVFDEAIVAALEPPVIKKSKKCAIL"
     gene            complement(605300..605432)
                     /locus_tag="tI(UAU)L"
                     /db_xref="GeneID:850931"
     tRNA            complement(join(605300..605335,605396..605432))
                     /locus_tag="tI(UAU)L"
                     /product="tRNA-Ile"
                     /note="Isoleucine tRNA (tRNA-Ile), predicted by
                     tRNAscan-SE analysis"
                     /db_xref="SGD:S000006614"
                     /db_xref="GeneID:850931"
     gene            complement(<605758..>607119)
                     /gene="BNA5"
                     /locus_tag="YLR231C"
                     /db_xref="GeneID:850933"
     mRNA            complement(<605758..>607119)
                     /gene="BNA5"
                     /locus_tag="YLR231C"
                     /product="kynureninase"
                     /transcript_id="NM_001182118.1"
                     /db_xref="GI:296146768"
                     /db_xref="GeneID:850933"
     CDS             complement(605758..607119)
                     /gene="BNA5"
                     /locus_tag="YLR231C"
                     /EC_number="3.7.1.3"
                     /note="Kynureninase; required for the de novo biosynthesis
                     of NAD from tryptophan via kynurenine; expression
                     regulated by Hst1p"
                     /codon_start=1
                     /product="kynureninase"
                     /protein_id="NP_013332.1"
                     /db_xref="GI:6323261"
                     /db_xref="SGD:S000004221"
                     /db_xref="GeneID:850933"
                     /translation="MEKALELDGEYPESLRDEFNIPTFKSMGLSSDDKPVTYLCGNSL
                     GLMPKSTRNSINAELDAWSDCAVESHFKHPEEARGKVPWVSIDLPILPLLAPIVGAQE
                     NEVAVMNSLTANLNSLLITFYKPTEKRFKILFEKGSFPSDYYAFYNQCKIHGISEPEN
                     VFIQIEPREGETYIRTQDILDTIEVNQDELALVCLSGVQYYTGQYFDIGRITSFAHQF
                     PDILVGWDLAHAVGNVPLQLHDWGVDFACWCSYKYLNAGPGGIGGLFVHSKHTKPDPA
                     KESLPRLAGWWGNDPAKRFQMLEVFEPIPGALGFRQSNPSVIDTVALRSSLELFAKFN
                     GINEVRKRSLLLTNYMTELLEASKYYKHPLRIEKLPCFFTILTPTSTDEEHGAQLSLY
                     FDSDTGKEDIMPKVFQYLHDHGVIGDARRPNVIRLAPAPLYNTFSDVYIAVNALNEAM
                     DKL"
     gene            complement(<607425..>609524)
                     /gene="EST1"
                     /locus_tag="YLR233C"
                     /db_xref="GeneID:850934"
     mRNA            complement(<607425..>609524)
                     /gene="EST1"
                     /locus_tag="YLR233C"
                     /product="Est1p"
                     /transcript_id="NM_001182120.1"
                     /db_xref="GI:296146769"
                     /db_xref="GeneID:850934"
     CDS             complement(607425..609524)
                     /gene="EST1"
                     /locus_tag="YLR233C"
                     /note="TLC1 RNA-associated factor involved in telomere
                     length regulation; recruitment subunit of telomerase; has
                     G-quadruplex promoting activity required for telomere
                     elongation; possible role in activating telomere-bound
                     Est2p-TLC1-RNA; EST1 has a paralog, EBS1, that arose from
                     the whole genome duplication"
                     /codon_start=1
                     /product="Est1p"
                     /protein_id="NP_013334.1"
                     /db_xref="GI:6323262"
                     /db_xref="SGD:S000004223"
                     /db_xref="GeneID:850934"
                     /translation="MDNEEVNEECMRLFFKNARAHLDKHLTSRLTCDENAYITFRCFL
                     DGIHRKSTRFLEELLLKQENMYHNNNYERINDSVIPLVLKLLWLQIHEPTLQWFEHWF
                     HDIMRLSNRRKFRVFRIFQKKMIQFFKITHRYYYDIIEHLCAKYDMNSVISNALFAKL
                     NLMQYTDGLSTHEKIILNTSNPLTFSIVISLQRCVINLGSTHFYKTLLNKPSNKPKSV
                     EGFEKSIRYLNIASLYLPAVGDTYFQRAKIYLITGKFSLYFFELVRGALVRIPSKCAL
                     NNLKDFILTPDFPERRRLMKKLAILVSKDLKGEKSFFEGQIVLQFLSIVEHTLVPQSW
                     NASRASNCWLLKEHLQMAALKYHSGNINVILENLAATMGSFDLMFTTRKSKEQKNKLK
                     YADLSERQVFFLDLSFDFIANIIDVVIKPSWQKNMEDFRYLAIIRLLMCWIKSYRSIL
                     QYTHRHRKFCTSFALLLNDLINSPLNCSGNIYSHRPKRSYLFREDIIFREFSCINFAL
                     TDFNDDYVYDSPDMINNIIGCPTLTKVLSPKEECVLRIRSIIFSGMKFLEKNDTGVIW
                     NASKYKFDLISPNIKIKRQIALSEISSKINVKTQQERVVSSRKVEAKRDEQQRKRAGK
                     IAVTELEKQFANVRRTKKLSPLPEKDGVSSELVKHAASRGRKTITGPLSSDFLSYPDE
                     AIDADEDITVQVPDTPT"
     gene            <609783..>611753
                     /gene="TOP3"
                     /locus_tag="YLR234W"
                     /gene_synonym="EDR1"
                     /db_xref="GeneID:850935"
     mRNA            <609783..>611753
                     /gene="TOP3"
                     /locus_tag="YLR234W"
                     /gene_synonym="EDR1"
                     /product="DNA topoisomerase 3"
                     /transcript_id="NM_001182121.1"
                     /db_xref="GI:296146770"
                     /db_xref="GeneID:850935"
     CDS             609783..611753
                     /gene="TOP3"
                     /locus_tag="YLR234W"
                     /gene_synonym="EDR1"
                     /EC_number="5.99.1.2"
                     /note="DNA Topoisomerase III; conserved protein that
                     functions in a complex with Sgs1p and Rmi1p to relax
                     single-stranded negatively-supercoiled DNA preferentially;
                     DNA catenation/decatenation activity stimulated by RPA and
                     Sgs1p-Top2p-Rmi1p; involved in telomere stability and
                     regulation of mitotic recombination"
                     /codon_start=1
                     /product="DNA topoisomerase 3"
                     /protein_id="NP_013335.1"
                     /db_xref="GI:6323263"
                     /db_xref="SGD:S000004224"
                     /db_xref="GeneID:850935"
                     /translation="MKVLCVAEKNSIAKAVSQILGGGRSTSRDSGYMYVKNYDFMFSG
                     FPFARNGANCEVTMTSVAGHLTGIDFSHDSHGWGKCAIQELFDAPLNEIMNNNQKKIA
                     SNIKREARNADYLMIWTDCDREGEYIGWEIWQEAKRGNRLIQNDQVYRAVFSHLERQH
                     ILNAARNPSRLDMKSVHAVGTRIEIDLRAGVTFTRLLTETLRNKLRNQATMTKDGAKH
                     RGGNKNDSQVVSYGTCQFPTLGFVVDRFERIRNFVPEEFWYIQLVVENKDNGGTTTFQ
                     WDRGHLFDRLSVLTFYETCIETAGNVAQVVDLKSKPTTKYRPLPLTTVELQKNCARYL
                     RLNAKQSLDAAEKLYQKGFISYPRTETDTFPHAMDLKSLVEKQAQLDQLAAGGRTAWA
                     SYAASLLQPENTSNNNKFKFPRSGSHDDKAHPPIHPIVSLGPEANVSPVERRVYEYVA
                     RHFLACCSEDAKGQSMTLVLDWAVERFSASGLVVLERNFLDVYPWARWETTKQLPRLE
                     MNALVDIAKAEMKAGTTAPPKPMTESELILLMDTNGIGTDATIAEHIDKIQVRNYVRS
                     EKVGKETYLQPTTLGVSLVHGFEAIGLEDSFAKPFQRREMEQDLKKICEGHASKTDVV
                     KDIVEKYRKYWHKTNACKNTLLQVYDRVKASM"
     gene            <612367..>614163
                     /gene="THI7"
                     /locus_tag="YLR237W"
                     /gene_synonym="THI10"
                     /db_xref="GeneID:850938"
     mRNA            <612367..>614163
                     /gene="THI7"
                     /locus_tag="YLR237W"
                     /gene_synonym="THI10"
                     /product="Thi7p"
                     /transcript_id="NM_001182124.1"
                     /db_xref="GI:296146771"
                     /db_xref="GeneID:850938"
     CDS             612367..614163
                     /gene="THI7"
                     /locus_tag="YLR237W"
                     /gene_synonym="THI10"
                     /note="Plasma membrane transporter responsible for the
                     uptake of thiamine; contributes to uptake of
                     5-aminoimidazole-4-carboxamide-1-beta-D-ribofuranoside
                     (acadesine); member of the major facilitator superfamily
                     of transporters; mutation of human ortholog causes
                     thiamine-responsive megaloblastic anemia"
                     /codon_start=1
                     /product="Thi7p"
                     /protein_id="NP_013338.1"
                     /db_xref="GI:6323266"
                     /db_xref="SGD:S000004227"
                     /db_xref="GeneID:850938"
                     /translation="MSFGSKVSRALRFLEIPVKDRASVSFLKNPDLQPIKSANQTWGF
                     WSNFAYWGVMSFSVGTWMSASSALGVGLSYPETIGTFIVGDVLTIIFTLANSCPGYDW
                     KVGFTLAQRFVFGIYGSAFGIIIRILMSIVNYGSNAWVGGLCINMILDSWSHHYLHLP
                     NTLSSKVAMTTKELIGFIIFHVLTAFCYLMKPYHMNYILIWSCVATFFSMLGMVIYLA
                     KQAHGVGELFTSTKSTATGSTKAWAWVYMISYWFGSVSPGSTNQSDYSRFGSSNWAIW
                     AGTICALLIPTTLIPVFGVIGASTCDKLYGEQYWMPMDIFNHWLTTNYSAGARAGAFF
                     CGLSFVLSQMSYTISNCGFASGMDLAGLLPKYVDIKRGALFAACVSWACLPWNFYNSS
                     STFLTVMSSFGVVMTPIISVMICDNFLIRKRQYSITNAFILKGEYYFTKGVNWRAIVA
                     WVCGMTPGLPGIAWEVNNDYFHNTGIVNFFYGDSFFSFLISFFVYWGLCLLFPFKITV
                     KHDDKDYYGAFTDEEARKKGMVPYSEISEEEIRAYTLGEGYTTGHEYRPEGSDDEIPE
                     LVKTSSENTNEFEIVHHKNNEKQSSTASEKAA"
     gene            <614755..>616191
                     /gene="FAR10"
                     /locus_tag="YLR238W"
                     /db_xref="GeneID:850939"
     mRNA            <614755..>616191
                     /gene="FAR10"
                     /locus_tag="YLR238W"
                     /product="Far10p"
                     /transcript_id="NM_001182125.1"
                     /db_xref="GI:296146772"
                     /db_xref="GeneID:850939"
     CDS             614755..616191
                     /gene="FAR10"
                     /locus_tag="YLR238W"
                     /note="Protein involved in recovery from arrest in
                     response to pheromone; acts in a cell cycle arrest
                     recovery pathway independent from Far1p; interacts with
                     Far3p, Far7p, Far8p, Far9p, and Far11p; potential Cdc28p
                     substrate; FAR10 has a paralog, VPS64, that arose from the
                     whole genome duplication"
                     /codon_start=1
                     /product="Far10p"
                     /protein_id="NP_013339.1"
                     /db_xref="GI:6323267"
                     /db_xref="SGD:S000004228"
                     /db_xref="GeneID:850939"
                     /translation="MTGPGPEINKEEHPSSPGKKQITYNSIPKNANLIDGSTNSSKRP
                     IEKYDKRIADPTKSYFPHSISRTPRRKYTYILVLTSLNGTFESKHVVIPFKPDGLKLG
                     RPVANSNSSSSSSLRGGKRVDSHTFSQVRSDNGNFDSRVLSRNHALLSCDPLTGKVYI
                     RDLKSSNGTFINGQRIGSNDVEIKVGDVIDLGTDIDTKIEHRKISATVEELFVQPLLE
                     SPIFENEDSDDCHTITEKEEAAAITSHIYGDSNNLELEEVILGSDTEILSGIFINNCI
                     GTSPTLSNIIKTLAMEIPFSKCDNFKLQSMENFLINYTTHLEYTNKLLVEKNDQQLVK
                     LQNGLRRKLSGKYEKIIEQNRNQVKQLERDHMFFKKSFEVKKRRNNEKQKSMEREIED
                     LKTRLEVERYKNSQMMKKNKQKEQELSTASKKKTTEHDTRGVPGMNPKGTDKFSIKNT
                     LCNHFTLLTFGTISIGIIAIVFKILSPN"
     gene            complement(<616332..>617318)
                     /gene="LIP2"
                     /locus_tag="YLR239C"
                     /db_xref="GeneID:850940"
     mRNA            complement(<616332..>617318)
                     /gene="LIP2"
                     /locus_tag="YLR239C"
                     /product="lipoyl(octanoyl) transferase LIP2"
                     /transcript_id="NM_001182126.1"
                     /db_xref="GI:296146773"
                     /db_xref="GeneID:850940"
     CDS             complement(616332..617318)
                     /gene="LIP2"
                     /locus_tag="YLR239C"
                     /EC_number="2.3.1.181"
                     /note="Lipoyl ligase; involved in the modification of
                     mitochondrial enzymes by the attachment of lipoic acid
                     groups"
                     /codon_start=1
                     /product="lipoyl(octanoyl) transferase LIP2"
                     /protein_id="NP_013340.1"
                     /db_xref="GI:6323268"
                     /db_xref="SGD:S000004229"
                     /db_xref="GeneID:850940"
                     /translation="MSRCIRQSVCTNFNVCRRQCFSTYASALKEMTHPIKPSAQTLRH
                     LQFTQRIPFQKGLEIQETLVRANLDIKDIQSKIERKLIQLDEEYKGTATINDNEKRIL
                     DKVMAMKPNPIILTFEFEPTYTGGKRIKKTMTPDQIAAYESFIPETQKDNPRPKFVQV
                     ERGGQVTFHGPGQIVIYIILDLKTFQSFPAKCLVSCIEQATIRTLKNTKMCDDTDKPL
                     NLDAMTTKDTGVWVENGKKKVASVGIHVRRSITSHGVAINVNTDLSYMNSFEMCGLKN
                     TLTTSIMEQRPDAVVNVQSVAISFVKEMTKLLGIKTLERMQIDDVNILKKNP"
     gene            <617533..>620160
                     /gene="VPS34"
                     /locus_tag="YLR240W"
                     /gene_synonym="END12; PEP15; STT8; VPL7; VPS7; VPT29"
                     /db_xref="GeneID:850941"
     mRNA            <617533..>620160
                     /gene="VPS34"
                     /locus_tag="YLR240W"
                     /gene_synonym="END12; PEP15; STT8; VPL7; VPS7; VPT29"
                     /product="phosphatidylinositol 3-kinase VPS34"
                     /transcript_id="NM_001182127.1"
                     /db_xref="GI:296146774"
                     /db_xref="GeneID:850941"
     CDS             617533..620160
                     /gene="VPS34"
                     /locus_tag="YLR240W"
                     /gene_synonym="END12; PEP15; STT8; VPL7; VPS7; VPT29"
                     /EC_number="2.7.1.137"
                     /note="Phosphatidylinositol (PI) 3-kinase that synthesizes
                     PI-3-phosphate; forms membrane-associated signal
                     transduction complex with Vps15p to regulate protein
                     sorting; activated by the GTP-bound form of Gpa1p; a
                     fraction is localized, with Vps15p, to nuclear pores at
                     nucleus-vacuole junctions and may facilitate transcription
                     elongation for genes positioned at the nuclear periphery"
                     /codon_start=1
                     /product="phosphatidylinositol 3-kinase VPS34"
                     /protein_id="NP_013341.1"
                     /db_xref="GI:6323269"
                     /db_xref="SGD:S000004230"
                     /db_xref="GeneID:850941"
                     /translation="MSLNNITFCVSQDLDVPLKVKIKSLEGHKPLLKPSQKILNPELM
                     LIGSNVFPSSDLIVSLQVFDKERNRNLTLPIYTPYIPFRNSRTWDYWLTLPIRIKQLT
                     FSSHLRIILWEYNGSKQIPFFNLETSIFNLKDCTLKRGFESLKFRYDVIDHCEVVTDN
                     KDQENLNKYFQGEFTRLPWLDEITISKLRKQRENRTWPQGTFVLNLEFPMLELPVVFI
                     EREIMNTQMNIPTLKNNPGLSTDLREPNRNDPQIKISLGDKYHSTLKFYDPDQPNNDP
                     IEEKYRRLERASKNANLDKQVKPDIKKRDYLNKIINYPPGTKLTAHEKGSIWKYRYYL
                     MNNKKALTKLLQSTNLREESERVEVLELMDSWAEIDIDDALELLGSTFKNLSVRSYAV
                     NRLKKASDKELELYLLQLVEAVCFENLSTFSDKSNSEFTIVDAVSSQKLSGDSMLLST
                     SHANQKLLKSISSESETSGTESLPIVISPLAEFLIRRALVNPRLGSFFYWYLKSESED
                     KPYLDQILSSFWSRLDKKSRNILNDQVRLINVLRECCETIKRLKDTTAKKMELLVHLL
                     ETKVRPLVKVRPIALPLDPDVLICDVCPETSKVFKSSLSPLKITFKTTLNQPYHLMFK
                     VGDDLRQDQLVVQIISLMNELLKNENVDLKLTPYKILATGPQEGAIEFIPNDTLASIL
                     SKYHGILGYLKLHYPDENATLGVQGWVLDNFVKSCAGYCVITYILGVGDRHLDNLLVT
                     PDGHFFHADFGYILGQDPKPFPPLMKLPPQIIEAFGGAESSNYDKFRSYCFVAYSILR
                     RNAGLILNLFELMKTSNIPDIRIDPNGAILRVRERFNLNMSEEDATVHFQNLINDSVN
                     ALLPIVIDHLHNLAQYWRT"
     gene            <620473..>622821
                     /locus_tag="YLR241W"
                     /db_xref="GeneID:850942"
     mRNA            <620473..>622821
                     /locus_tag="YLR241W"
                     /product="hypothetical protein"
                     /transcript_id="NM_001182128.1"
                     /db_xref="GI:296146775"
                     /db_xref="GeneID:850942"
     CDS             620473..622821
                     /locus_tag="YLR241W"
                     /note="hypothetical protein; may be involved in
                     detoxification"
                     /codon_start=1
                     /product="hypothetical protein"
                     /protein_id="NP_013342.1"
                     /db_xref="GI:6323270"
                     /db_xref="SGD:S000004231"
                     /db_xref="GeneID:850942"
                     /translation="MTSYIERLKSAASYLDTVPDEHHDFRKPTAKVVTTQLTIATSLG
                     IFALLSFSILLKKWPRLYASRRYKDDGNLRLPSWNQSSLFGWLTVLYKIRDEQILEYA
                     GLDAYVFLSFFKMCIKLLSIFCFFSVCVISPVRYHFTGKIDDGNDDDDSESSLIHLVK
                     RIVEGSGDGDNHSAPERTNVYLWMYVLFTYFFTFIAIKMAVAETKHVVSTRQAYLGKQ
                     NTITDRTIRLSGIPIELRDSEALKTRIEQLKIGTVSSITICREWGPLNKLFHCRKKIL
                     KNLELKYSECPRELRTRQPYSENYHLLGNEQSGAVTHGENVPSSNNNDEDTILYSQIS
                     LGERPKMKIGYRGIFGKEVDAIEYLEQQLKFIDAEIIEARKQHYSATPTAFVTMDSVA
                     NAQMAAQAVLDPRVHYFITRLAPAPHDIKWDHVCLSRKDRLTKVYSTTVFIGLSSLFL
                     VIPVSYLATLLNLKTLSKFWPSVGQLLKDHQWAANIVTGLLPTYLFTLLNFGIPYFYE
                     YLTSYQGLVSYSEEEISLVSKNFFYIFVNLFLVFTLAGTASNYWAYLSDTTKIAYQLA
                     TSVKEFSLFYVDLIILQGIGMFPFKLLLVGSLIGFPLVKIKAKTPRQRNELYNPPIFN
                     FGLQLPQPILILIITLIYSVMSTKILTSGLAYFIIGFYVYKYQLIFATDHLPHSTGKV
                     WPLIFRRIIVGLLLFQLTMTGTLAGFEGGWVLSSCLFPLPVVTLCFLYDFEKNYLPLS
                     KYIALSSIREYERDNSTVNSANEEESYAYPYAVSELEGPMLD"
     gene            complement(<622918..>623883)
                     /gene="ARV1"
                     /locus_tag="YLR242C"
                     /db_xref="GeneID:850943"
     mRNA            complement(<622918..>623883)
                     /gene="ARV1"
                     /locus_tag="YLR242C"
                     /product="Arv1p"
                     /transcript_id="NM_001182129.1"
                     /db_xref="GI:296146776"
                     /db_xref="GeneID:850943"
     CDS             complement(622918..623883)
                     /gene="ARV1"
                     /locus_tag="YLR242C"
                     /note="Cortical ER protein; implicated in the membrane
                     insertion of tail-anchored C-terminal single transmembrane
                     domain proteins; may function in transport of
                     glycosylphosphatidylinositol intermediates into ER lumen;
                     required for normal intracellular sterol distribution;
                     human ARV1 required for normal cholesterol and bile acid
                     homeostasis; similar to Nup120p"
                     /codon_start=1
                     /product="Arv1p"
                     /protein_id="NP_013343.1"
                     /db_xref="GI:6323271"
                     /db_xref="SGD:S000004232"
                     /db_xref="GeneID:850943"
                     /translation="MICITCMRPVDSLYTVYSNDHIQLTDCPYCQETVDKYVEIDNVL
                     LFIDLLLLKAGAYRHLVFNALELHLSKYPKRKALNDCQCLRDYTQALLFNVKNWFCKY
                     DRLNRLWLLLLSFEIYLTWVTEESKYIYYLNRNNNDGKLIMLSKKLPESFKWDSAIMR
                     NTITSKVFTWSPPIQYLYFASYCILDVSLFHTFTQYFILKKLHWKHYSVSSKDVISYT
                     ILLSYGAKIFPILMLIWPYDTLISMSIIKWVANLYIIESLKIVTNLSYWNIIKIFISV
                     SLLRYFMVKPILIVFVAKFNFSVIKNLIHQEFILLLQKSGTYLLL"
     rep_origin      623198..623861
                     /note="ARS1219;
                     Replication origin; identified in multiple array studies,
                     confirmed by plasmid-based recombinational ARS assay"
                     /db_xref="SGD:S000130183"
     gene            <624203..>625021
                     /gene="GPN3"
                     /locus_tag="YLR243W"
                     /db_xref="GeneID:850944"
     mRNA            <624203..>625021
                     /gene="GPN3"
                     /locus_tag="YLR243W"
                     /product="Gpn3p"
                     /transcript_id="NM_001182130.1"
                     /db_xref="GI:296146777"
                     /db_xref="GeneID:850944"
     CDS             624203..625021
                     /gene="GPN3"
                     /locus_tag="YLR243W"
                     /note="Putative GTPase with a role in biogenesis of RNA
                     pol II and polIII; may be involved in assembly of RNA
                     polymerases II and III and in their transport into the
                     nucleus; may have a role in sister chromatid cohesion;
                     contains a Gly-Pro-Asn motif in the G domain; similar to
                     Npa3p and Gpn2p"
                     /codon_start=1
                     /product="Gpn3p"
                     /protein_id="NP_013344.1"
                     /db_xref="GI:6323272"
                     /db_xref="SGD:S000004233"
                     /db_xref="GeneID:850944"
                     /translation="MSRVGVMVLGPAGAGKSTFCNSIISHMQTVGRRAHIVNLDPAAE
                     ATKYEFTIDIRDLISLDDVMEEMDLGPNGALIYCFEYLLKNLDWLDEEIGDFNDEYLI
                     FDCPGQIELYTHIPVLPNIVRHLTQQLNFNLCATYLLEAPFVIDSSKFFSGALSAMSA
                     MILLELPHINVLSKLDLIKGDINKKKLKRFLNPDAMLLMETEGMNQASNPKFLRLNQC
                     IANLVDDFGMVQFLPLESNNPDSIETILSYVDDITQWAEGQEQKEPNDQIDVEE"
     gene            complement(<625168..>626331)
                     /gene="MAP1"
                     /locus_tag="YLR244C"
                     /db_xref="GeneID:850945"
     mRNA            complement(<625168..>626331)
                     /gene="MAP1"
                     /locus_tag="YLR244C"
                     /product="Map1p"
                     /transcript_id="NM_001182131.1"
                     /db_xref="GI:296146778"
                     /db_xref="GeneID:850945"
     CDS             complement(625168..626331)
                     /gene="MAP1"
                     /locus_tag="YLR244C"
                     /EC_number="3.4.11.18"
                     /note="Methionine aminopeptidase; catalyzes the
                     cotranslational removal of N-terminal methionine from
                     nascent polypeptides; function is partially redundant with
                     that of Map2p"
                     /codon_start=1
                     /product="Map1p"
                     /protein_id="NP_013345.1"
                     /db_xref="GI:6323273"
                     /db_xref="SGD:S000004234"
                     /db_xref="GeneID:850945"
                     /translation="MSTATTTVTTSDQASHPTKIYCSGLQCGRETSSQMKCPVCLKQG
                     IVSIFCDTSCYENNYKAHKALHNAKDGLEGAYDPFPKFKYSGKVKASYPLTPRRYVPE
                     DIPKPDWAANGLPVSEQRNDRLNNIPIYKKDQIKKIRKACMLGREVLDIAAAHVRPGI
                     TTDELDEIVHNETIKRGAYPSPLNYYNFPKSLCTSVNEVICHGVPDKTVLKEGDIVNL
                     DVSLYYQGYHADLNETYYVGENISKEALNTTETSRECLKLAIKMCKPGTTFQELGDHI
                     EKHATENKCSVVRTYCGHGVGEFFHCSPNIPHYAKNRTPGVMKPGMVFTIEPMINEGT
                     WKDMTWPDDWTSTTQDGKLSAQFEHTLLVTEHGVEILTARNKKSPGGPRQRIK"
     gene            complement(<626502..>626930)
                     /gene="CDD1"
                     /locus_tag="YLR245C"
                     /db_xref="GeneID:850946"
     mRNA            complement(<626502..>626930)
                     /gene="CDD1"
                     /locus_tag="YLR245C"
                     /product="cytidine deaminase"
                     /transcript_id="NM_001182132.1"
                     /db_xref="GI:296146779"
                     /db_xref="GeneID:850946"
     CDS             complement(626502..626930)
                     /gene="CDD1"
                     /locus_tag="YLR245C"
                     /EC_number="3.5.4.5"
                     /note="Cytidine deaminase; catalyzes the modification of
                     cytidine to uridine in vitro but native RNA substrates
                     have not been identified, localizes to both the nucleus
                     and cytoplasm"
                     /codon_start=1
                     /product="cytidine deaminase"
                     /protein_id="NP_013346.1"
                     /db_xref="GI:6323274"
                     /db_xref="SGD:S000004235"
                     /db_xref="GeneID:850946"
                     /translation="MKVGGIEDRQLEALKRAALKACELSYSPYSHFRVGCSILTNNDV
                     IFTGANVENASYSNCICAERSAMIQVLMAGHRSGWKCMVICGDSEDQCVSPCGVCRQF
                     INEFVVKDFPIVMLNSTGSRSKVMTMGELLPMAFGPSHLN"
     gene            <627118..>628197
                     /gene="ERF2"
                     /locus_tag="YLR246W"
                     /db_xref="GeneID:850947"
     mRNA            <627118..>628197
                     /gene="ERF2"
                     /locus_tag="YLR246W"
                     /product="Erf2p"
                     /transcript_id="NM_001182133.1"
                     /db_xref="GI:296146780"
                     /db_xref="GeneID:850947"
     CDS             627118..628197
                     /gene="ERF2"
                     /locus_tag="YLR246W"
                     /EC_number="2.3.1.225"
                     /note="Subunit of a palmitoyltransferase; this complex
                     adds a palmitoyl lipid moiety to heterolipidated
                     substrates such as Ras1p and Ras2p through a thioester
                     linkage; mutants partially mislocalize Ras2p to the
                     vacuole; palmitoyltransferase is composed of Erf2p and
                     Shr5p"
                     /codon_start=1
                     /product="Erf2p"
                     /protein_id="NP_013347.1"
                     /db_xref="GI:6323275"
                     /db_xref="SGD:S000004236"
                     /db_xref="GeneID:850947"
                     /translation="MALVSRRSTRSESTSITKEEHTGEGSLTKLFFRWLVTLEGDQDI
                     NDGKGYISLPNVSNYIFFLGGRFRTVKGAKPLWLGVLLAIVCPMVLFSIFEAHKLWHT
                     QNGYKVLVIFFYYFWVITLASFIRTATSDPGVLPRNIHLSQLRNNYQIPQEYYNLITL
                     PTHSSISKDITIKYCPSCRIWRPPRSSHCSTCNVCVMVHDHHCIWVNNCIGKRNYRFF
                     LIFLLGAILSSVILLTNCAIHIARESGGPRDCPVAILLLCYAGLTLWYPAILFTYHIF
                     MAGNQQTTREFLKGIGSKKNPVFHRVVKEENIYNKGSFLKNMGHLMLEPRGPSFVSAR
                     KPHEAGDWRFMDLSPAHSFEKIQKI"
     gene            628383..628497
                     /locus_tag="tL(CAA)L"
                     /db_xref="GeneID:850948"
     tRNA            join(628383..628420,628454..628497)
                     /locus_tag="tL(CAA)L"
                     /product="tRNA-Leu"
                     /note="Leucine tRNA (tRNA-Leu), predicted by tRNAscan-SE
                     analysis"
                     /db_xref="SGD:S000006643"
                     /db_xref="GeneID:850948"
     gene            complement(<628684..>633354)
                     /gene="IRC20"
                     /locus_tag="YLR247C"
                     /db_xref="GeneID:850949"
     mRNA            complement(<628684..>633354)
                     /gene="IRC20"
                     /locus_tag="YLR247C"
                     /product="Irc20p"
                     /transcript_id="NM_001182134.1"
                     /db_xref="GI:296146781"
                     /db_xref="GeneID:850949"
     CDS             complement(628684..633354)
                     /gene="IRC20"
                     /locus_tag="YLR247C"
                     /EC_number="3.6.1.-"
                     /note="E3 ubiquitin ligase and putative helicase; involved
                     in synthesis-dependent strand annealing-mediated
                     homologous recombination; ensures precise end-joining
                     along with Srs2p in the Yku70p/Yku80p/Lig4p-dependent
                     nonhomologous end joining (NHEJ) pathway; localizes to
                     both the mitochondrion and the nucleus; contains a
                     Snf2/Swi2 family ATPase/helicase and a RING finger domain;
                     interacts with Cdc48p and Smt3p; null mutant displays
                     increased levels of spontaneous Rad52p foci"
                     /codon_start=1
                     /product="Irc20p"
                     /protein_id="NP_013348.1"
                     /db_xref="GI:6323276"
                     /db_xref="SGD:S000004237"
                     /db_xref="GeneID:850949"
                     /translation="MSAVGALLAREYNVTAEKCDFFLENGSFDSVIAALPALNQEQET
                     VTQKVSKNGKELINVASVNIEIPERISLSNNGRQLFKFIVDIEILPCENDNEATLVVS
                     SDSVSLFQIGFKMENNSKIAVDKQLPLILDICAHKNQERALRNQLENRKSLERKPSRK
                     RRKKNSNVNDPEKLLKSRIHELSLSYKDFECSPVVFRYNDSSLTWVLSFNLKLKFLNN
                     KFNRFSVEANQILDLTFSNRDENEFERYHKHSHIHSNFIQKQFISQILEYSKDRLSKI
                     KPFLPQSIPDLKVNLLPFQRESVEWMLIKEGHGNSLSDTPTVIDEVGLIDFMNEYYAY
                     GYELIARSPDEVGPSLLWNKLTGYILTTEDAAHLYNQYRKERLSGDYPVCAKGVLAEE
                     MGLGKTIEILSLILLNRRKLKDSEATFIDDENRTITKTKTTLIICPNAILKQWLEEIE
                     LHANSLKWYTYRGYNEIMKDCKTVDEAVQQLCQYDIIVTSYNIIATEVHHAEFNRSIR
                     SRRLKSPKYDYSSPLALMQFYRIILDEVQMLRSSSTYSAKCTSLLHRIHTWGVSGTPI
                     QNIYNFRMIMSYLKLHPFCDEVDFIRTLQEEIKLRNEAKDYTSNDFVCQLKGVRFSIK
                     DCMNIFYRYDLCIRHSKANVASQIHIPRQHNFIIPLEFAPIEWDNYLNLWNNFLELSG
                     YNSDGSGSPRVSNAFLNEWLSRLRYICCHALFPEILSTRQKRLHGHLSRISNIDDILI
                     SMRMDAFDSLIGYYRERFHLSIKQAQYELEISNTPAKALESFIKIRDDLMIHIRQKFN
                     VEDPFDKSLNLSEDEDEHMDERFGEKETSSGDESDREINGAKNHDNHNNDGMLSNHLK
                     KKGLRAMMNLLHDCYFFLGSVYYNLGTRKLEEADDKHRKEKTEEVVYSDVFPKNELEE
                     IEENRLLEQENYANAEILRKSILSSEARKVDMTIKMARTKFAPMTSNIPLRLINIEFD
                     HKNDYSSNLAVSRCFKSLSKLIEGLNEQTKNFNELLDELLIIIYEPVHRTEDDDSTNK
                     IIGNEEYSTSIDSQDKIFSLLGCLEIILQNRDNILTSESEVKIPKHLVPEGSIISKYQ
                     KQLLNSLRLISGTPLRTVFDELKNSRIVRRISSSNESESTIQNFEDYLLQYEVESKSL
                     FKYNKQVRESLKILGSIYNAKTEYYSQLQRISDSLVSLHSLSAPQLSHLIRTINKSLG
                     GTLDAKINNIESRLIYLKNLSRLKDTLNDNQILSCSICLGEVEIGAIIKCGHYFCKSC
                     ILTWLRAHSKCPICKGFCSISEVYNFKFKNSTEKREKEIQEPRREGADSSQDNSNENS
                     IISNMSEVEKLFGNKYEQFHQINEVHQIHIKESFGAKIDFVIKLISYLRLKSEQENAD
                     PPQVILYSQKTEYLKVIGKVLKLYHIEHLACLSNTANVGETINNFKRQPSVTCLLLNV
                     KTLGAGLNLINAKHIFLLDPILNNSDELQAMGRNNRIGQDEETFVWNFMIRNTVEENI
                     LRYKCILEERKRKEKSKKGDKYDEAQDETDNEESDDAKFEISVVDQEVSNEHLWNCFF
                     HGSD"
     STS             633081..633487
                     /standard_name="D1S3698"
                     /db_xref="UniSTS:474276"
     gene            <634252..>636084
                     /gene="RCK2"
                     /locus_tag="YLR248W"
                     /gene_synonym="CLK1; CMK3"
                     /db_xref="GeneID:850950"
     mRNA            <634252..>636084
                     /gene="RCK2"
                     /locus_tag="YLR248W"
                     /gene_synonym="CLK1; CMK3"
                     /product="Rck2p"
                     /transcript_id="NM_001182135.1"
                     /db_xref="GI:296146782"
                     /db_xref="GeneID:850950"
     CDS             634252..636084
                     /gene="RCK2"
                     /locus_tag="YLR248W"
                     /gene_synonym="CLK1; CMK3"
                     /EC_number="2.7.11.1"
                     /note="Protein kinase involved in response to oxidative
                     and osmotic stress; identified as suppressor of S. pombe
                     cell cycle checkpoint mutations; similar to CaM
                     (calmodulin) kinases; RCK2 has a paralog, RCK1, that arose
                     from the whole genome duplication"
                     /codon_start=1
                     /product="Rck2p"
                     /protein_id="NP_013349.1"
                     /db_xref="GI:6323277"
                     /db_xref="SGD:S000004238"
                     /db_xref="GeneID:850950"
                     /translation="MLKIKALFSKKKPDQADLSQESKKPFKGKTRSSGTNNKDVSQIT
                     SSPKKSFQDKNIVQYPSVVADDHHMKSLTDELVTTIDSDSSPSDNITTENVETVTSVP
                     AIDVHESSEGQLSSDPLISDESLSEQSEIISDIQDDSTDDDNMEDEIPEKSFLEQKEL
                     IGYKLINKIGEGAFSKVFRAIPAKNSSNEFLTKNYKAVAIKVIKKADLSSINGDHRKK
                     DKGKDSTKTSSRDQVLKEVALHKTVSAGCSQIVAFIDFQETDSYYYIIQELLTGGEIF
                     GEIVRLTYFSEDLSRHVIKQLALAVKHMHSLGVVHRDIKPENLLFEPIEFTRSIKPKL
                     RKSDDPQTKADEGIFTPGVGGGGIGIVKLADFGLSKQIFSKNTKTPCGTVGYTAPEVV
                     KDEHYSMKVDMWGIGCVLYTMLCGFPPFYDEKIDTLTEKISRGEYTFLKPWWDEISAG
                     AKNAVAKLLELEPSKRYDIDQFLDDPWLNTFDCLPKEGESSQKKAGTSERRHPHKKQF
                     QLFQRDSSLLFSPAAVAMRDAFDIGNAVKRTEEDRMGTRGGLGSLAEDEELEDSYSGA
                     QGDEQLEQNMFQLTLDTSTILQRRKKVQENDVGPTIPISATIRE"
     gene            <636780..>639914
                     /gene="YEF3"
                     /locus_tag="YLR249W"
                     /gene_synonym="TEF3"
                     /db_xref="GeneID:850951"
     mRNA            <636780..>639914
                     /gene="YEF3"
                     /locus_tag="YLR249W"
                     /gene_synonym="TEF3"
                     /product="translation elongation factor eEF1B subunit
                     gamma"
                     /transcript_id="NM_001182136.1"
                     /db_xref="GI:296146783"
                     /db_xref="GeneID:850951"
     CDS             636780..639914
                     /gene="YEF3"
                     /locus_tag="YLR249W"
                     /gene_synonym="TEF3"
                     /note="Gamma subunit of translational elongation factor
                     eEF1B; stimulates the binding of aminoacyl-tRNA (AA-tRNA)
                     to ribosomes by releasing eEF1A (Tef1p/Tef2p) from the
                     ribosomal complex; contains two ABC cassettes; binds and
                     hydrolyzes ATP; YEF3 has a paralog, HEF3, that arose from
                     the whole genome duplication"
                     /codon_start=1
                     /product="translation elongation factor eEF1B subunit
                     gamma"
                     /protein_id="NP_013350.1"
                     /db_xref="GI:6323278"
                     /db_xref="SGD:S000004239"
                     /db_xref="GeneID:850951"
                     /translation="MSDSQQSIKVLEELFQKLSVATADNRHEIASEVASFLNGNIIEH
                     DVPEHFFGELAKGIKDKKTAANAMQAVAHIANQSNLSPSVEPYIVQLVPAICTNAGNK
                     DKEIQSVASETLISIVNAVNPVAIKALLPHLTNAIVETNKWQEKIAILAAISAMVDAA
                     KDQVALRMPELIPVLSETMWDTKKEVKAAATAAMTKATETVDNKDIERFIPSLIQCIA
                     DPTEVPETVHLLGATTFVAEVTPATLSIMVPLLSRGLNERETGIKRKSAVIIDNMCKL
                     VEDPQVIAPFLGKLLPGLKSNFATIADPEAREVTLRALKTLRRVGNVGEDDAIPEVSH
                     AGDVSTTLQVVNELLKDETVAPRFKIVVEYIAAIGADLIDERIIDQQAWFTHITPYMT
                     IFLHEKKAKDILDEFRKRAVDNIPVGPNFDDEEDEGEDLCNCEFSLAYGAKILLNKTQ
                     LRLKRARRYGICGPNGCGKSTLMRAIANGQVDGFPTQEECRTVYVEHDIDGTHSDTSV
                     LDFVFESGVGTKEAIKDKLIEFGFTDEMIAMPISALSGGWKMKLALARAVLRNADILL
                     LDEPTNHLDTVNVAWLVNYLNTCGITSITISHDSVFLDNVCEYIINYEGLKLRKYKGN
                     FTEFVKKCPAAKAYEELSNTDLEFKFPEPGYLEGVKTKQKAIVKVTNMEFQYPGTSKP
                     QITDINFQCSLSSRIAVIGPNGAGKSTLINVLTGELLPTSGEVYTHENCRIAYIKQHA
                     FAHIESHLDKTPSEYIQWRFQTGEDRETMDRANRQINENDAEAMNKIFKIEGTPRRIA
                     GIHSRRKFKNTYEYECSFLLGENIGMKSERWVPMMSVDNAWIPRGELVESHSKMVAEV
                     DMKEALASGQFRPLTRKEIEEHCSMLGLDPEIVSHSRIRGLSGGQKVKLVLAAGTWQR
                     PHLIVLDEPTNYLDRDSLGALSKALKEFEGGVIIITHSAEFTKNLTEEVWAVKDGRMT
                     PSGHNWVSGQGAGPRIEKKEDEEDKFDAMGNKIAGGKKKKKLSSAELRKKKKERMKKK
                     KELGDAYVSSDEEF"
     gene            <640317..>641021
                     /gene="SSP120"
                     /locus_tag="YLR250W"
                     /db_xref="GeneID:850952"
     mRNA            <640317..>641021
                     /gene="SSP120"
                     /locus_tag="YLR250W"
                     /product="Ssp120p"
                     /transcript_id="NM_001182137.1"
                     /db_xref="GI:296146784"
                     /db_xref="GeneID:850952"
     CDS             640317..641021
                     /gene="SSP120"
                     /locus_tag="YLR250W"
                     /note="hypothetical protein; green fluorescent protein
                     (GFP)-fusion protein localizes to the cytoplasm in a
                     punctate pattern"
                     /codon_start=1
                     /product="Ssp120p"
                     /protein_id="NP_013351.1"
                     /db_xref="GI:6323279"
                     /db_xref="SGD:S000004240"
                     /db_xref="GeneID:850952"
                     /translation="MRFLRGFVFSLAFTLYKVTATAEIGSEINVENEAPPDGLSWEEW
                     HMDHEHQLKDYTPETFFALHDIKKKGFLDENDILSLYGLNREEIVGAGDGMGQHDESE
                     KIDNEMAKRVVSLIMRLLDVDDNTKITKEEYLQFAKRGNKFPDLGVGVGHHSDFELEY
                     EIHHWNKFHKDKDPDVKVVHKEDIEHELLHHEHEIEHEEEIQRGASRATVITDDELES
                     RIELKNIPEKFKNGIF"
     gene            <641464..>642057
                     /gene="SYM1"
                     /locus_tag="YLR251W"
                     /db_xref="GeneID:850953"
     mRNA            <641464..>642057
                     /gene="SYM1"
                     /locus_tag="YLR251W"
                     /product="Sym1p"
                     /transcript_id="NM_001182138.1"
                     /db_xref="GI:296146785"
                     /db_xref="GeneID:850953"
     CDS             641464..642057
                     /gene="SYM1"
                     /locus_tag="YLR251W"
                     /note="Protein required for ethanol metabolism; induced by
                     heat shock and localized to the inner mitochondrial
                     membrane; homologous to mammalian peroxisomal membrane
                     protein Mpv17"
                     /codon_start=1
                     /product="Sym1p"
                     /protein_id="NP_013352.1"
                     /db_xref="GI:6323280"
                     /db_xref="SGD:S000004241"
                     /db_xref="GeneID:850953"
                     /translation="MKLLHLYEASLKRRPKTTNAIMTGALFGIGDVSAQLLFPTSKVN
                     KGYDYKRTARAVIYGSLIFSFIGDKWYKILNNKIYMRNRPQYHWSNMVLRVAVDQLAF
                     APLGLPFYFTCMSIMEGRSFDVAKLKIKEQWWPTLLTNWAVWPLFQAINFSVVPLQHR
                     LLAVNVVAIFWNTYLSYKNSKVMEKDKVPVHYPPVVE"
     gene            <642627..>644336
                     /gene="MCP2"
                     /locus_tag="YLR253W"
                     /db_xref="GeneID:850955"
     mRNA            <642627..>644336
                     /gene="MCP2"
                     /locus_tag="YLR253W"
                     /product="Mcp2p"
                     /transcript_id="NM_001182140.1"
                     /db_xref="GI:296146786"
                     /db_xref="GeneID:850955"
     CDS             642627..644336
                     /gene="MCP2"
                     /locus_tag="YLR253W"
                     /note="Mitochondrial hypothetical protein involved in
                     lipid homeostasis; integral membrane protein that
                     localizes to the mitochondrial inner membrane; involved in
                     mitochondrial morphology; non-essential gene which
                     interacts genetically with MDM10, and other members of the
                     ERMES complex; transcription is periodic during the
                     metabolic cycle; homologous to human aarF domain
                     containing kinase, ADCK1"
                     /codon_start=1
                     /product="Mcp2p"
                     /protein_id="NP_013354.1"
                     /db_xref="GI:6323282"
                     /db_xref="SGD:S000004243"
                     /db_xref="GeneID:850955"
                     /translation="MMTKAFFNKLPFEVFRRYVRTGKSIPQRSPRTRKSLLVGGTIAS
                     AVVLYNFNDTFHDSVKHTALTTKRIAVVTQATTRCFYHYKRALNKSYENKKEREVALN
                     KCHKMCALITLHALRSNGGIYIKLGQHIGAMTYLLPKEWTDTMIPLQDHCPESTYEEI
                     DELFKEDLGTSIEDMFLEFNKTPIGVASLAQVHVAKLKNSDGKGSSVAVKCQHPSLKE
                     FIPLDVMLTRTVFELLDVFFPDYPLTWLGDELQSSIYVELNFTKEAENAEKTRHYFSK
                     FKKQTALKIPKVIESHKRILIMEYVGGKRLDDLEYIDSHGISRSEVSSCLSHIFNNMI
                     FTPNVGIHCDPHGGNLAIRSVKPAKDNGYHNFEIVLFDHGLYRYPSTRTRRLYAKFWL
                     SLLFDKDQTKMKKYAKGFANITDEQFPLLAAAITGRSIDAALNYDISTSRTQEEMDVM
                     ANGILEGTLLSDLMSILSRIPRVVLLILKTNDLTRHLDECLQNPLGPERTFLIMTQYC
                     AKTVYDEKVERINSEYARWSIKWMWENLTNWIVYERRINQLYFYDFVLWWKKFIPKTW
                     LSS"
     gene            complement(<644404..>644973)
                     /gene="NDL1"
                     /locus_tag="YLR254C"
                     /db_xref="GeneID:850956"
     mRNA            complement(<644404..>644973)
                     /gene="NDL1"
                     /locus_tag="YLR254C"
                     /product="Ndl1p"
                     /transcript_id="NM_001182141.1"
                     /db_xref="GI:296146787"
                     /db_xref="GeneID:850956"
     CDS             complement(644404..644973)
                     /gene="NDL1"
                     /locus_tag="YLR254C"
                     /note="Homolog of nuclear distribution factor NudE; NUDEL;
                     interacts with Pac1p and regulates dynein targeting to
                     microtubule plus ends"
                     /codon_start=1
                     /product="Ndl1p"
                     /protein_id="NP_013355.1"
                     /db_xref="GI:6323283"
                     /db_xref="SGD:S000004244"
                     /db_xref="GeneID:850956"
                     /translation="MVPNLDLETAIQIISSLETQLSELEGATKEYENDLEQVISKLKS
                     DLLESQQQNKCNKKQITDLEIQVDELENENIQLRNKIETLQLESDRRLERNVLLEHEL
                     LDTKEALQKLRVSKEEATSGETRRNTRSLPSQNKKMKLFKDTIKVSTTSSTLYLQNMA
                     KTNNAARSHCNIPNTQITQSTVIATTSSV"
     gene            <646415..>650923
                     /gene="HAP1"
                     /locus_tag="YLR256W"
                     /gene_synonym="CYP1"
                     /db_xref="GeneID:850958"
     mRNA            <646415..>650923
                     /gene="HAP1"
                     /locus_tag="YLR256W"
                     /gene_synonym="CYP1"
                     /product="Hap1p"
                     /transcript_id="NM_001182143.1"
                     /db_xref="GI:296146788"
                     /db_xref="GeneID:850958"
     CDS             646415..650923
                     /gene="HAP1"
                     /locus_tag="YLR256W"
                     /gene_synonym="CYP1"
                     /note="Zinc finger transcription factor; involved in the
                     complex regulation of gene expression in response to
                     levels of heme and oxygen; the S288C sequence differs from
                     other strain backgrounds due to a Ty1 insertion in the
                     carboxy terminus"
                     /codon_start=1
                     /product="Hap1p"
                     /protein_id="NP_013357.1"
                     /db_xref="GI:6323285"
                     /db_xref="SGD:S000004246"
                     /db_xref="GeneID:850958"
                     /translation="MSNTPYNSSVPSIASMTQSSVSRSPNMHTATTPGANTSSNSPPL
                     HMSSDSSKIKRKRNRIPLSCTICRKRKVKCDKLRPHCQQCTKTGVAHLCHYMEQTWAE
                     EAEKELLKDNELKKLRERVKSLEKTLSKVHSSPSSNSLKSYNTPESSNLFMGSDEHTT
                     LVNANTGSASSASHMHQQQQQQQQQEQQQDFSRSANANANSSSLSISNKYDNDELDLT
                     KDFDLLHIKSNGTIHLGATHWLSIMKGDPYLKLLWGHIFAMREKLNEWYYQKNSYSKL
                     KSSKCPINHAQAPPSAAAAATRKCPVDHSAFSSGMVAPKEETPLPRKCPVDHTMFSSG
                     MIPPREDTSSQKRCPVDHTMYSAGMMPPKDETPSPFSTKAMIDHNKHTMNPPQSKCPV
                     DHRNYMKDYPSDMANSSSNPASRCPIDHSSMKNTAALPASTHNTIPHHQPQSGSHARS
                     HPAQSRKHDSYMTESEVLATLCEMLPPKRVIALFIEKFFKHLYPAIPILDEQNFKNHV
                     NQMLSLSSMNPTVNNFGMSMPSSSTLENQPITQINLPKLSDSCNLGILIIILRLTWLS
                     IPSNSCEVDLGEESGSFLVPNESSNMSASALTSMAKEESLLLKHETPVEALELCQKYL
                     IKFDELSSISNNNVNLTTVQFAIFYNFYMKSASNDLTTLTNTNNTGMANPGHDSESHQ
                     ILLSNITQMAFSCGLHRDPDNFPQLNATIPATSQDVSNNGSKKANPSTNPTLNNNMSA
                     ATTNSSSRSGSADSRSGSNPVNKKENQVSIERFKHTWRKIWYYIVSMDVNQSLSLGSP
                     RLLRNLRDFSDTKLPSASRIDYVRDIKELIIVKNFTLFFQIDLCIIAVLNHILNVSLA
                     RSVRKFELDSLINLLKNLTYGTENVNDVVSSLINKGLLPTSEGGSVDSNNDEIYGLPK
                     LPDILNHGQHNQNLYADGRNTSSSDIDKKLDLPHESTTRALFFSKHMTIRMLLYLLNY
                     ILFTHYEPMGSEDPGTNILAKEYAQEALNFAMDGYRNCMIFFNNIRNTNSLFDYMNVI
                     LSYPCLDIGHRSLQFIVCLILRAKCGPLTGMRESSIITNGTSSGFNSSVEDEDVKVKQ
                     ESSDELKKDDFMKDVNLDSGDSLAEILMSRMLLFQKLTKQLSKKYNYAIRMNKSTGFF
                     VSLLDTPSKKSDSKSGGSSFMLGNWKHPKVSNMSGFLAGDKDQLQKCPVYQDALGFVS
                     PTGANEGSAPMQGMSLQGSTARMGGTQLPPIRSYKPITYTSSNLRRMNETGEAEAKRR
                     RFNDGYIDNNSNNDIPRGISPKPSNGLSSVQPLLSSFSMNQLNGGTIPTVPSLTNITS
                     QMGALPSLDRITTNQINLPDPSRDEAFDNSIKQMTPMTSAFMNANTTIPSSTLNGNMN
                     MNGAGTANTDTSANGSALSTLTSPQGSDLASNSATQYKPDLEDFLMQNSNFNGLMINP
                     SSLVEVVGGYNDPNNLGRNDAVDFLPVDNVEIDGVGIKINYHLLTSIYVTSILSYTVL
                     EDDANDEK"
     mobile_element  650824..656743
                     /note="YLRWTy1-3; Ty1 element, LTR retrotransposon of the
                     Copia (Pseudoviridae) group; contains co-transcribed genes
                     TYA Gag and TYB Pol, encoding proteins involved in
                     structure and function of virus-like particles, flanked by
                     two direct repeats"
                     /mobile_element_type="retrotransposon:YLRWTy1-3"
                     /db_xref="SGD:S000007099"
     LTR             650824..651157
                     /note="Ty1 LTR"
                     /db_xref="SGD:S000007088"
     gene            <651117..>652439
                     /locus_tag="YLR256W-A"
                     /db_xref="GeneID:850959"
     mRNA            <651117..>652439
                     /locus_tag="YLR256W-A"
                     /product="gag protein"
                     /transcript_id="NM_001184409.1"
                     /db_xref="GI:296146789"
                     /db_xref="GeneID:850959"
     CDS             651117..652439
                     /locus_tag="YLR256W-A"
                     /note="Retrotransposon TYA Gag gene co-transcribed with
                     TYB Pol; translated as TYA or TYA-TYB polyprotein; Gag is
                     a nucleocapsid protein that is the structural constituent
                     of virus-like particles (VLPs); similar to retroviral Gag"
                     /codon_start=1
                     /product="gag protein"
                     /protein_id="NP_058173.1"
                     /db_xref="GI:7839188"
                     /db_xref="SGD:S000007377"
                     /db_xref="GeneID:850959"
                     /translation="MESQQLSQHPHISHGSACASVTSKEVHTNQDPLDVSASKTEECE
                     KASTKANSQQTTTPASSAVPENPHHASPQPASVPPPQNGPYPQQCMMTQNQANPSGWS
                     FYGHPSMIPYTPYQMSPMYFPPGPQSQFPQYPSSVGTPLSTPSPESGNTFTDSSSADS
                     DMTSTKKYVRPPPMLTSPNDFPNWVKTYIKFLQNSNLGGIIPTVNGKPVRQITDDELT
                     FLYNTFQIFAPSQFLPTWVKDILSVDYTDIMKILSKSIEKMQSDTQEANDIVTLANLQ
                     YNGSTPADAFETKVTNIIDRLNNNGIHINNKVACQLIMRGLSGEYKFLRYTRHRHLNM
                     TVAELFLDIHAIYEEQQGSRNSKPNYRRNLSDEKNDSRSYTNTTKPKVIARNPQKTNN
                     SKSKTARAHNVSTSNNSPSTDNDSISKSTTEPIQLNNKHDLHLRPGTY"
     LTR             656410..656743
                     /note="Ty1 LTR"
                     /db_xref="SGD:S000007089"
     gene            complement(656934..657006)
                     /locus_tag="tA(AGC)L"
                     /db_xref="GeneID:850960"
     tRNA            complement(656934..657006)
                     /locus_tag="tA(AGC)L"
                     /product="tRNA-Ala"
                     /note="Alanine tRNA (tRNA-Ala), predicted by tRNAscan-SE
                     analysis; one of 11 nuclear tRNA genes containing the
                     tDNA-anticodon AGC (converted to IGC in the mature tRNA),
                     decodes GCU and GCC codons into alanine, one of 16 nuclear
                     tRNAs for alanine"
                     /db_xref="SGD:S000006517"
                     /db_xref="GeneID:850960"
     LTR             657022..657365
                     /note="Ty3 LTR"
                     /db_xref="SGD:S000007096"
     LTR             657449..657767
                     /note="Ty1 LTR"
                     /db_xref="SGD:S000007090"
     gene            <658826..>659791
                     /locus_tag="YLR257W"
                     /db_xref="GeneID:850961"
     mRNA            <658826..>659791
                     /locus_tag="YLR257W"
                     /product="hypothetical protein"
                     /transcript_id="NM_001182144.1"
                     /db_xref="GI:296146790"
                     /db_xref="GeneID:850961"
     CDS             658826..659791
                     /locus_tag="YLR257W"
                     /note="hypothetical protein; protein abundance increases
                     in response to DNA replication stress"
                     /codon_start=1
                     /product="hypothetical protein"
                     /protein_id="NP_013358.1"
                     /db_xref="GI:6323286"
                     /db_xref="SGD:S000004247"
                     /db_xref="GeneID:850961"
                     /translation="MVDARGSTPCLIGDSIRNVNDGNSLDFQYTNQFNEESEASRLLT
                     PQTSSNHALSKMQKDDDIRDRSYTSVAELNREGALLTDEVDLENVDASKVRSNRDDLE
                     AEEKRKKLLLLKKKQRNKSINSESFSSPSLRASKSNSLITSTDPVEDHISKYSSSGTP
                     ENITGEADDEDEDIIRNSYGQMIKNNSNRPHLAKGESYQSAEQEIDHTAPEKSEKRQE
                     RSGRSFDRQKSSAEFLRSLSRSISRGPTKNKTVSPSKGEDSRMYSTSNYSISLVDLEN
                     GPKIIPETLEEEQEDAEKEGVLMEDEGNEEYTKDLEEAANKAQPQ"
     rep_origin      659824..660072
                     /note="ARS1220;
                     Autonomously Replicating Sequence"
                     /db_xref="SGD:S000118478"
     gene            <660716..>662833
                     /gene="GSY2"
                     /locus_tag="YLR258W"
                     /db_xref="GeneID:850962"
     mRNA            <660716..>662833
                     /gene="GSY2"
                     /locus_tag="YLR258W"
                     /product="glycogen (starch) synthase GSY2"
                     /transcript_id="NM_001182145.1"
                     /db_xref="GI:296146791"
                     /db_xref="GeneID:850962"
     CDS             660716..662833
                     /gene="GSY2"
                     /locus_tag="YLR258W"
                     /EC_number="2.4.1.11"
                     /note="Glycogen synthase; expression induced by glucose
                     limitation, nitrogen starvation, heat shock, and
                     stationary phase; activity regulated by cAMP-dependent,
                     Snf1p and Pho85p kinases as well as by the Gac1p-Glc7p
                     phosphatase; GSY2 has a paralog, GSY1, that arose from the
                     whole genome duplication; relocalizes from cytoplasm to
                     plasma membrane upon DNA replication stress"
                     /codon_start=1
                     /product="glycogen (starch) synthase GSY2"
                     /protein_id="NP_013359.1"
                     /db_xref="GI:6323287"
                     /db_xref="SGD:S000004248"
                     /db_xref="GeneID:850962"
                     /translation="MSRDLQNHLLFETATEVANRVGGIYSVLKSKAPITVAQYKDHYH
                     LIGPLNKATYQNEVDILDWKKPEAFSDEMRPVQHALQTMESRGVHFVYGRWLIEGAPK
                     VILFDLDSVRGYSNEWKGDLWSLVGIPSPENDFETNDAILLGYTVAWFLGEVAHLDSQ
                     HAIVAHFHEWLAGVALPLCRKRRIDVVTIFTTHATLLGRYLCASGSFDFYNCLESVDV
                     DHEAGRFGIYHRYCIERAAAHSADVFTTVSQITAFEAEHLLKRKPDGILPNGLNVIKF
                     QAFHEFQNLHALKKEKINDFVRGHFHGCFDFDLDNTLYFFIAGRYEYKNKGADMFIEA
                     LARLNYRLKVSGSKKTVVAFIVMPAKNNSFTVEALKGQAEVRALENTVHEVTTSIGKR
                     IFDHAIRYPHNGLTTELPTDLGELLKSSDKVMLKRRILALRRPEGQLPPIVTHNMVDD
                     ANDLILNKIRQVQLFNSPSDRVKMIFHPEFLNANNPILGLDYDEFVRGCHLGVFPSYY
                     EPWGYTPAECTVMGVPSITTNVSGFGAYMEDLIETNQAKDYGIYIVDRRFKAPDESVE
                     QLVDYMEEFVKKTRRQRINQRNRTERLSDLLDWKRMGLEYVKARQLALRRGYPDQFRE
                     LVGEELNDSNMDALAGGKKLKVARPLSVPGSPRDLRSNSTVYMTPGDLGTLQEVNNAD
                     DYFSLGVNPAADDDDDGPYADDS"
     gene            complement(<663284..>665002)
                     /gene="HSP60"
                     /locus_tag="YLR259C"
                     /gene_synonym="CPN60; MIF4; MNA2"
                     /db_xref="GeneID:850963"
     mRNA            complement(<663284..>665002)
                     /gene="HSP60"
                     /locus_tag="YLR259C"
                     /gene_synonym="CPN60; MIF4; MNA2"
                     /product="chaperone ATPase HSP60"
                     /transcript_id="NM_001182146.1"
                     /db_xref="GI:296146792"
                     /db_xref="GeneID:850963"
     CDS             complement(663284..665002)
                     /gene="HSP60"
                     /locus_tag="YLR259C"
                     /gene_synonym="CPN60; MIF4; MNA2"
                     /note="Tetradecameric mitochondrial chaperonin; required
                     for ATP-dependent folding of precursor polypeptides and
                     complex assembly; prevents aggregation and mediates
                     protein refolding after heat shock; role in mtDNA
                     transmission; phosphorylated"
                     /codon_start=1
                     /product="chaperone ATPase HSP60"
                     /protein_id="NP_013360.1"
                     /db_xref="GI:6323288"
                     /db_xref="SGD:S000004249"
                     /db_xref="GeneID:850963"
                     /translation="MLRSSVVRSRATLRPLLRRAYSSHKELKFGVEGRASLLKGVETL
                     AEAVAATLGPKGRNVLIEQPFGPPKITKDGVTVAKSIVLKDKFENMGAKLLQEVASKT
                     NEAAGDGTTSATVLGRAIFTESVKNVAAGCNPMDLRRGSQVAVEKVIEFLSANKKEIT
                     TSEEIAQVATISANGDSHVGKLLASAMEKVGKEGVITIREGRTLEDELEVTEGMRFDR
                     GFISPYFITDPKSSKVEFEKPLLLLSEKKISSIQDILPALEISNQSRRPLLIIAEDVD
                     GEALAACILNKLRGQVKVCAVKAPGFGDNRKNTIGDIAVLTGGTVFTEELDLKPEQCT
                     IENLGSCDSITVTKEDTVILNGSGPKEAIQERIEQIKGSIDITTTNSYEKEKLQERLA
                     KLSGGVAVIRVGGASEVEVGEKKDRYDDALNATRAAVEEGILPGGGTALVKASRVLDE
                     VVVDNFDQKLGVDIIRKAITRPAKQIIENAGEEGSVIIGKLIDEYGDDFAKGYDASKS
                     EYTDMLATGIIDPFKVVRSGLVDASGVASLLATTEVAIVDAPEPPAAAGAGGMPGGMP
                     GMPGMM"
     gene            <665844..>667907
                     /gene="LCB5"
                     /locus_tag="YLR260W"
                     /db_xref="GeneID:850964"
     mRNA            <665844..>667907
                     /gene="LCB5"
                     /locus_tag="YLR260W"
                     /product="sphinganine kinase LCB5"
                     /transcript_id="NM_001182147.1"
                     /db_xref="GI:296146793"
                     /db_xref="GeneID:850964"
     CDS             665844..667907
                     /gene="LCB5"
                     /locus_tag="YLR260W"
                     /EC_number="2.7.1.91"
                     /note="Minor sphingoid long-chain base kinase; possibly
                     involved in synthesis of long-chain base phosphates, which
                     function as signaling molecules; LCB5 has a paralog, LCB4,
                     that arose from the whole genome duplication"
                     /codon_start=1
                     /product="sphinganine kinase LCB5"
                     /protein_id="NP_013361.1"
                     /db_xref="GI:6323289"
                     /db_xref="SGD:S000004250"
                     /db_xref="GeneID:850964"
                     /translation="MTLKPSKRRKGRSRHSRKKQITSAILTEEGIMIKAKPSSPYTYA
                     NRMADKRSRSSIDNISRTSFQSNISRTSFQSNSDNNSIFETASLISCVTCLSDTDTID
                     RSETSTTDTSKDDLSANPKLHYPSVNGQLPANTVIPYGRILDARYIEKEPLHYYDANS
                     SPSSPLSSSMSNISEKCDLDELESSQKKERKGNSLSRGSNSSSSLLTSRSPFTKLVEV
                     IFARPRRHDVVPKRVSLYIDYKPHSSSHLKEEDDLVEEILKRSYKNTRRNKSIFVIIN
                     PFGGKGKAKKLFMTKAKPLLLASRCSIEVVYTKYPGHAIEIAREMDIDKYDTIACASG
                     DGIPHEVINGLYQRPDHVKAFNNIAITEIPCGSGNAMSVSCHWTNNPSYSTLCLIKSI
                     ETRIDLMCCSQPSYAREHPKLSFLSQTYGLIAETDINTEFIRWMGPARFELGVAFNII
                     QKKKYPCEIYVKYAAKSKNELKNHYLEHKNKGSLEFQHITMNKDNEDCDNYNYENEYE
                     TENEDEDEDADADDEDSHLISRDLADSSADQIKEEDFKIKYPLDEGIPSDWERLDPNI
                     SNNLGIFYTGKMPYVAADTKFFPAALPSDGTMDMVITDARTSLTRMAPILLGLDKGSH
                     VLQPEVLHSKILAYKIIPKLGNGLFSVDGEKFPLEPLQVEIMPRLCKTLLRNGRYVDT
                     DFDSM"
     gene            complement(<668244..>668891)
                     /gene="YPT6"
                     /locus_tag="YLR262C"
                     /db_xref="GeneID:850966"
     mRNA            complement(<668244..>668891)
                     /gene="YPT6"
                     /locus_tag="YLR262C"
                     /product="Rab family GTPase YPT6"
                     /transcript_id="NM_001182149.1"
                     /db_xref="GI:296146794"
                     /db_xref="GeneID:850966"
     CDS             complement(668244..668891)
                     /gene="YPT6"
                     /locus_tag="YLR262C"
                     /note="Rab family GTPase; Ras-like GTP binding protein
                     involved in the secretory pathway, required for fusion of
                     endosome-derived vesicles with the late Golgi, maturation
                     of the vacuolar carboxypeptidase Y; resides temporarily at
                     the Golgi, dissociates into cytosol upon arrival of the
                     Rab GTPaseYpt32p, which also functions in the late Golgi;
                     Golgi-localized form is bound to GTP, while cytosolic form
                     is GDP-bound; homolog of the mammalian Rab6"
                     /codon_start=1
                     /product="Rab family GTPase YPT6"
                     /protein_id="NP_013363.1"
                     /db_xref="GI:6323291"
                     /db_xref="SGD:S000004252"
                     /db_xref="GeneID:850966"
                     /translation="MSRSGKSLTKYKIVFLGEQGVGKTSLITRFMYDTFDDHYQATIG
                     IDFLSKTMYLDDKTIRLQLWDTAGQERFRSLIPSYIRDSRVAIIVYDITKRKSFEYID
                     KWIEDVKNERGDENVILCIVGNKSDLSDERQISTEEGEKKAKLLGAKIFMETSTKAGY
                     NVKALFKKIAKSLPEFQNSESTPLDSENANSANQNKPGVIDISTAEEQEQSACQC"
     gene            complement(<669468..>669662)
                     /gene="TMA7"
                     /locus_tag="YLR262C-A"
                     /db_xref="GeneID:850967"
     mRNA            complement(<669468..>669662)
                     /gene="TMA7"
                     /locus_tag="YLR262C-A"
                     /product="Tma7p"
                     /transcript_id="NM_001184339.1"
                     /db_xref="GI:296146795"
                     /db_xref="GeneID:850967"
     CDS             complement(669468..669662)
                     /gene="TMA7"
                     /locus_tag="YLR262C-A"
                     /note="Protein of unknown that associates with ribosomes;
                     null mutant exhibits translation defects, altered
                     polyribosome profiles, and resistance to the translation
                     inhibitor anisomcyin; protein abundance increases in
                     response to DNA replication stress"
                     /codon_start=1
                     /product="Tma7p"
                     /protein_id="NP_013364.1"
                     /db_xref="GI:6323292"
                     /db_xref="SGD:S000007246"
                     /db_xref="GeneID:850967"
                     /translation="MSSRQGGKMKPLKQKKKQQQDLDPEDIAFKEKQKADAAAKKALM
                     ANMKSGKPLVGGGIKKSGKK"
     gene            <670340..>672823
                     /gene="RED1"
                     /locus_tag="YLR263W"
                     /db_xref="GeneID:850968"
     mRNA            <670340..>672823
                     /gene="RED1"
                     /locus_tag="YLR263W"
                     /product="Red1p"
                     /transcript_id="NM_001182150.1"
                     /db_xref="GI:296146796"
                     /db_xref="GeneID:850968"
     CDS             670340..672823
                     /gene="RED1"
                     /locus_tag="YLR263W"
                     /note="Protein component of the synaptonemal complex axial
                     elements; involved in chromosome segregation during the
                     first meiotic division; critical for coupling checkpoint
                     signaling to SC formation; promotes interhomolog
                     recombination by phosphorylating Hop1p; also interacts
                     with Mec3p and Ddc1p"
                     /codon_start=1
                     /product="Red1p"
                     /protein_id="NP_013365.1"
                     /db_xref="GI:6323293"
                     /db_xref="SGD:S000004253"
                     /db_xref="GeneID:850968"
                     /translation="MEGLKKKIFGVCLKNDLAQTRNETKGIHYGLMTLETSKQLQEFL
                     HLLVIKREVIQNFELLFHIINVAVKITDSNLPSDDIWHFILKLRFSSEINIDEDSKVL
                     NYLLETGIAMENPVSWKCLAVISSILSSVPQSKKIITNLIETEHAKKIGQLFDNIQDL
                     QQGNFLVEILSNCFKKSASNSKKVEKIPQLWQSRSKNKFFFENEFYPFSSKNGSLQTC
                     QFLCNNFMSTLSFTGILRQVSYSGSETLKNLRIFKKKDDENSYFIQCIYNKIYLWLDE
                     KAPLEFERKKIRITKNLKNKIQIKLRQPFHECVRTTADKTALLFNKTKGFQLEFEDEK
                     LGETFFHNVNNIPKISEVQNFLVLDYIEEEPENEGEEEEQIGRADEQKEDEEEESLDE
                     LSTPMVYPIKSSIPHNHNEKVQLVTPDRSVSIRSDEWDLKSNTEDEEGNVLADLKISS
                     TKETKRQTDYVHIDSEDQSPVVSAQMRKMRRESTKTLEILRQEFKDKDVQNKEDQSEQ
                     IQNPFVNTSSLVVGKSCLVNPKEKPNIDQTVVGITELKSNSSIKKRDINILDTIFGQP
                     PSKKQKQFHKKEKKKQQKKLTNFKPIIDVPSQDKRNLRSNAPTKPKSIKVSKLRTDKK
                     VTGEKSSPETAAEKVDDQTVRSNDEQAMSRATKEKCFPDVNEGKEITKDDAKVSLESK
                     KNNETFVDSSVVEKHTPPDKDCNNCNITDILESTTVIDLQSPHGLSAPGQNTFTNKLQ
                     EQIYSSINHFSNELVRKISIINQELNKKILKELSEKYQKLFSELQDNFQNDTNEMLKF
                     MGEIKDMMNLPEDQLVHAIRTRKFDNNKR"
     gene            <673131..>673334
                     /gene="RPS28B"
                     /locus_tag="YLR264W"
                     /gene_synonym="RPS33B"
                     /db_xref="GeneID:850969"
     mRNA            <673131..>673334
                     /gene="RPS28B"
                     /locus_tag="YLR264W"
                     /gene_synonym="RPS33B"
                     /product="ribosomal 40S subunit protein S28B"
                     /transcript_id="NM_001182151.1"
                     /db_xref="GI:296146797"
                     /db_xref="GeneID:850969"
     CDS             673131..673334
                     /gene="RPS28B"
                     /locus_tag="YLR264W"
                     /gene_synonym="RPS33B"
                     /note="Protein component of the small (40S) ribosomal
                     subunit; homologous to mammalian ribosomal protein S28, no
                     bacterial homolog; has an extraribosomal function in
                     autoregulation, in which Rps28Bp binds to a decapping
                     complex via Edc3p, which then binds to RPS28B mRNA leading
                     to its decapping and degradation; RPS28B has a paralog,
                     RPS28A, that arose from the whole genome duplication"
                     /codon_start=1
                     /product="ribosomal 40S subunit protein S28B"
                     /protein_id="NP_013366.1"
                     /db_xref="GI:6323294"
                     /db_xref="SGD:S000004254"
                     /db_xref="GeneID:850969"
                     /translation="MDSKTPVTLAKVIKVLGRTGSRGGVTQVRVEFLEDTSRTIVRNV
                     KGPVRENDILVLMESEREARRLR"
     gene            complement(<673828..>673944)
                     /locus_tag="YLR264C-A"
                     /db_xref="GeneID:1466417"
     mRNA            complement(<673828..>673944)
                     /locus_tag="YLR264C-A"
                     /product="hypothetical protein"
                     /transcript_id="NM_001184638.1"
                     /db_xref="GI:296146798"
                     /db_xref="GeneID:1466417"
     CDS             complement(673828..673944)
                     /locus_tag="YLR264C-A"
                     /codon_start=1
                     /product="hypothetical protein"
                     /protein_id="NP_878129.1"
                     /db_xref="GI:33438841"
                     /db_xref="SGD:S000028808"
                     /db_xref="GeneID:1466417"
                     /translation="MNVIFKLYLTIDAPKKKKVTVRDFLSIRYSMPYRLASN"
     gene            complement(<674427..>675455)
                     /gene="NEJ1"
                     /locus_tag="YLR265C"
                     /gene_synonym="LIF2"
                     /db_xref="GeneID:850970"
     mRNA            complement(<674427..>675455)
                     /gene="NEJ1"
                     /locus_tag="YLR265C"
                     /gene_synonym="LIF2"
                     /product="Nej1p"
                     /transcript_id="NM_001182152.1"
                     /db_xref="GI:296146799"
                     /db_xref="GeneID:850970"
     CDS             complement(674427..675455)
                     /gene="NEJ1"
                     /locus_tag="YLR265C"
                     /gene_synonym="LIF2"
                     /note="Protein involved in regulation of nonhomologous end
                     joining; interacts with DNA ligase IV components Dnl4p and
                     Lif1p; repressed by MAT heterozygosity; regulates cellular
                     distribution of Lif1p"
                     /codon_start=1
                     /product="Nej1p"
                     /protein_id="NP_013367.1"
                     /db_xref="GI:6323295"
                     /db_xref="SGD:S000004255"
                     /db_xref="GeneID:850970"
                     /translation="MDSELKGQQLSDAEWCVKKINGEGNCLLLFLPMSSPTTIVMIVL
                     VSLERLVPYVFKLSQTQLSQQCQSQGFTDSISLNLIKLKLMDILQAPQEINQIGLVDS
                     NLVFSFDVSADITVSINSVPSHVTKDMFYMILQSLCMLLLKLVNLSTQYHYVQRDILN
                     EKQKCLDFLLISLRDLDGGSKVISQWAPENSKNYESLQQCTDDDIIKKLLHKGKFQHQ
                     EFLADSLKTLLSLRNKFQDVSRFEESGELNKKERVRFPAVNHFYNDDFELQADPTNEA
                     RPNSRGKIKPKTDFKPKSRESSTSSQLRLENFSESEATPEKTKSSSSLVEEYPQKKRK
                     FGKVRIKN"
     gene            complement(<675619..>677724)
                     /gene="PDR8"
                     /locus_tag="YLR266C"
                     /db_xref="GeneID:850971"
     mRNA            complement(<675619..>677724)
                     /gene="PDR8"
                     /locus_tag="YLR266C"
                     /product="Pdr8p"
                     /transcript_id="NM_001182153.1"
                     /db_xref="GI:296146800"
                     /db_xref="GeneID:850971"
     CDS             complement(675619..677724)
                     /gene="PDR8"
                     /locus_tag="YLR266C"
                     /note="Transcription factor; targets include ATP-binding
                     cassette (ABC) transporters, major facilitator superfamily
                     transporters, and other genes involved in the pleiotropic
                     drug resistance (PDR) phenomenon; PDR8 has a paralog,
                     YRR1, that arose from the whole genome duplication"
                     /codon_start=1
                     /product="Pdr8p"
                     /protein_id="NP_013368.1"
                     /db_xref="GI:6323296"
                     /db_xref="SGD:S000004256"
                     /db_xref="GeneID:850971"
                     /translation="MDGSHFPMKSTTGEPVSSGKKGKRRKVIKSCAFCRKRKLKCSQA
                     RPMCQQCVIRKLPQCVYTEEFNYPLSNTELFEQVPNVALVQKIENLQTLLKENDNNNA
                     KPVYCRSSENPLRSLRTSVLGDNGSRYVFGPTSWKTLSLFEQNKFQTEFQNLWKVLKP
                     LPECTKSQLNENDVVADLPSFPQMESCIKSFFAGPLFGILHIFNQDDILSLLDRLFIR
                     DTTDKNLVILLDLQGNAKDKYNLGIVLQILCLGYYNQDIPSSVSHFLHTLSAASLSSS
                     SSNFVEKLQFFLLSYISVMINCTDGVWDATQGVDLINELCQGCISLGLNDIDKWYLNE
                     SEETKQNLRCIWFWALFLDVSTSYDIGNPPSISDDLLDLSIFTAQNFQSPSIDFRRVK
                     LMHDFLDVSRFTTREIHKREMNEKLTTFSLRLIEFIQSNFSPIEHYTNSVYYSDIDPF
                     DILILSRSLSIVASIYNIEMIIAQQSRIIDKNRMVQFLLISISVCVNTMVFHFKEPIN
                     DQENVLTEGLKLSIILINPLLIRIVSQVYSLAFNRLIFREKAFLFLIDLDTGKKIQFI
                     KYEEENFDELLTGFDVRTDKFLSFSGTIIRFYEIIDSIFAVNERNKRLLKAVSNFYQL
                     TSTLAFERVSRVLFDKASQARIETEKIWLKKGINMEHFSDLMIEDFINDVWKTFKEIS
                     KDLWSIDKKKFYKQYHFDL"
     gene            <678212..>679924
                     /gene="BOP2"
                     /locus_tag="YLR267W"
                     /db_xref="GeneID:850972"
     mRNA            <678212..>679924
                     /gene="BOP2"
                     /locus_tag="YLR267W"
                     /product="Bop2p"
                     /transcript_id="NM_001182154.1"
                     /db_xref="GI:296146801"
                     /db_xref="GeneID:850972"
     CDS             678212..679924
                     /gene="BOP2"
                     /locus_tag="YLR267W"
                     /codon_start=1
                     /product="Bop2p"
                     /protein_id="NP_013369.1"
                     /db_xref="GI:6323297"
                     /db_xref="SGD:S000004257"
                     /db_xref="GeneID:850972"
                     /translation="MVAALTYLPTELIQRIFEFTVVETDSQYWLYNLVALIDFSVSSR
                     GGGSITEDFLTNYVRKNLMVLDLTCEATQDSILRAEYGFLKRLLPYIDMDAQYIRVVD
                     LETNADKAQNLKAEKLIVIFDEFSDLKLIETFFPLANSNSNIIEFVFCVRNIKSSFYS
                     PLEKLHIANIVADIDINTLYLDFVDSNIYSDQNFFGIFDPDIFQLINKNYRNFFSKTN
                     EKGKKRPPICKKICFPFVETLNLDYMALDSFFNSILHKLTTKIKTFERNNEFDVDKNL
                     NLNSTTTVAALIIKSILQQFFNNFHISFPNLVTLNFIKMSTYPNNNEITQCCNFIDLS
                     SYVLNKCLSENISINFLFQLHSLKNWSMPKIKEFTGHKFKYDETTFSGSPERYIKSLR
                     GNIKILQEMAINETNDGTCYFRVKLIPEGVEKTQIINWIPFTSSFSDDTFKQRHHLKR
                     PMICLKNNSLRSLTVKIIRIEKCSSIRIQGFYLPNLQELFINNTLCDTTQHQKQASND
                     MSCIEFTSWNELPQCKKLGFAQLEDDSNYVLNISNLQDHLPNLDLRESFPTFFDIRQK
                     FVVV"
     gene            <680200..>680844
                     /gene="SEC22"
                     /locus_tag="YLR268W"
                     /gene_synonym="SLY2; TS26; TSL26"
                     /db_xref="GeneID:850973"
     mRNA            <680200..>680844
                     /gene="SEC22"
                     /locus_tag="YLR268W"
                     /gene_synonym="SLY2; TS26; TSL26"
                     /product="Sec22p"
                     /transcript_id="NM_001182155.1"
                     /db_xref="GI:296146802"
                     /db_xref="GeneID:850973"
     CDS             680200..680844
                     /gene="SEC22"
                     /locus_tag="YLR268W"
                     /gene_synonym="SLY2; TS26; TSL26"
                     /note="R-SNARE protein; assembles into SNARE complex with
                     Bet1p, Bos1p and Sed5p; cycles between the ER and Golgi
                     complex; involved in anterograde and retrograde transport
                     between the ER and Golgi; synaptobrevin homolog"
                     /codon_start=1
                     /product="Sec22p"
                     /protein_id="NP_013370.1"
                     /db_xref="GI:6323298"
                     /db_xref="SGD:S000004258"
                     /db_xref="GeneID:850973"
                     /translation="MIKSTLIYREDGLPLCTSVDNENDPSLFEQKQKVKIVVSRLTPQ
                     SATEATLESGSFEIHYLKKSMVYYFVICESGYPRNLAFSYLNDIAQEFEHSFANEYPK
                     PTVRPYQFVNFDNFLQMTKKSYSDKKVQDNLDQLNQELVGVKQIMSKNIEDLLYRGDS
                     LDKMSDMSSSLKETSKRYRKSAQKINFDLLISQYAPIVIVAFFFVFLFWWIFLK"
     gene            <681186..>682238
                     /gene="DCS1"
                     /locus_tag="YLR270W"
                     /db_xref="GeneID:850974"
     mRNA            <681186..>682238
                     /gene="DCS1"
                     /locus_tag="YLR270W"
                     /product="Dcs1p"
                     /transcript_id="NM_001182157.1"
                     /db_xref="GI:296146803"
                     /db_xref="GeneID:850974"
     CDS             681186..682238
                     /gene="DCS1"
                     /locus_tag="YLR270W"
                     /EC_number="3.6.1.59"
                     /note="Non-essential hydrolase involved in mRNA decapping;
                     activates Xrn1p; may function in a feedback mechanism to
                     regulate deadenylation, contains pyrophosphatase activity
                     and a HIT (histidine triad) motif; acts as inhibitor of
                     neutral trehalase Nth1p; required for growth on glycerol
                     medium; protein abundance increases in response to DNA
                     replication stress; DCS1 has a paralog, DCS2, that arose
                     from the whole genome duplication"
                     /codon_start=1
                     /product="Dcs1p"
                     /protein_id="NP_013372.1"
                     /db_xref="GI:6323299"
                     /db_xref="SGD:S000004260"
                     /db_xref="GeneID:850974"
                     /translation="MSQLPTDFASLIKRFQFVSVLDSNPQTKVMSLLGTIDNKDAIIT
                     AEKTHFLFDETVRRPSQDGRSTPVLYNCENEYSCINGIQELKEITSNDIYYWGLSVIK
                     QDMESNPTAKLNLIWPATPIHIKKYEQQNFHLVRETPEMYKRIVQPYIEEMCNNGRLK
                     WVNNILYEGAESERVVYKDFSEENKDDGFLILPDMKWDGMNLDSLYLVAIVYRTDIKT
                     IRDLRYSDRQWLINLNNKIRSIVPGCYNYAVHPDELRILVHYQPSYYHFHIHIVNIKH
                     PGLGNSIAAGKAILLEDIIEMLNYLGPEGYMNKTITYAIGENHDLWKRGLEEELTKQL
                     ERDGIPKIPKIVNGFK"
     gene            <682737..>683561
                     /locus_tag="YLR271W"
                     /db_xref="GeneID:850976"
     mRNA            <682737..>683561
                     /locus_tag="YLR271W"
                     /product="hypothetical protein"
                     /transcript_id="NM_001182158.1"
                     /db_xref="GI:296146804"
                     /db_xref="GeneID:850976"
     CDS             682737..683561
                     /locus_tag="YLR271W"
                     /note="hypothetical protein; green fluorescent protein
                     (GFP)-fusion protein localizes to the cytoplasm and the
                     nucleus and is induced in response to the DNA-damaging
                     agent MMS"
                     /codon_start=1
                     /product="hypothetical protein"
                     /protein_id="NP_013373.1"
                     /db_xref="GI:6323301"
                     /db_xref="SGD:S000004261"
                     /db_xref="GeneID:850976"
                     /translation="MEESKTKRKEDRIDLKNTPPQKKSKRDSTNDETARTSLRSIMPR
                     GYKMMENMGYKEGETLGSNESALKEPIKVEINTKRRGIRAEKPDPSTMNDMQMSEQRF
                     IKRESEMKNNKRLKKIWYRIQKVAFEMMGDSDLYNPGEDPRDFNVLWRSYVMQLNEEV
                     AKNDLNNHSNNDNEDKNNMIPMVNESLEASPAIKGEKFGRPSTLIDCDTSIIGSRITK
                     DTELAELEELSIEKRITKLNIFLRSEKYYCFFCGIKYKDEGDLYEHCPGVNEDDHK"
     gene            complement(<683672..>687202)
                     /gene="YCS4"
                     /locus_tag="YLR272C"
                     /gene_synonym="LOC7"
                     /db_xref="GeneID:850977"
     mRNA            complement(<683672..>687202)
                     /gene="YCS4"
                     /locus_tag="YLR272C"
                     /gene_synonym="LOC7"
                     /product="Ycs4p"
                     /transcript_id="NM_001182159.1"
                     /db_xref="GI:296146805"
                     /db_xref="GeneID:850977"
     CDS             complement(683672..687202)
                     /gene="YCS4"
                     /locus_tag="YLR272C"
                     /gene_synonym="LOC7"
                     /note="Subunit of the condensin complex; required for
                     establishment and maintenance of chromosome condensation,
                     chromosome segregation, chromatin binding of condensin,
                     tRNA gene clustering at the nucleolus, and silencing at
                     the mating type locus; required for replication slow zone
                     (RSZ) breakage following Mec1p inactivation"
                     /codon_start=1
                     /product="Ycs4p"
                     /protein_id="NP_013374.1"
                     /db_xref="GI:6323302"
                     /db_xref="SGD:S000004262"
                     /db_xref="GeneID:850977"
                     /translation="MSGFSLSEYLTKFQTTDRESYPRLQDPSRELNVIIDQLAVSPEQ
                     IDASPDSLEALIDLCHDFPHLTPKLQTQLSYLISSSLSNLSKDIKANLSSNVNFTEIG
                     GLIPQWKRHLEEYGYLIQVLLTFLQDELHKVSSQSTNLNRSAKNSKNDSANVELFKRD
                     CNQMENLLESITKLLEINLSKIFQTTPEKDLFIGLFTRPLFVLLEIEPVTKVSSLKMF
                     IQRILAMCVKNHGQSSSIQSSLMTNLTYFLHLSVFNAELLKLLNDEYNYPQLTEDILK
                     EISTRVFNAKDTTGPKAISNFLIKLSELSPGIMLRQMNLVITLLNNSSITLRCSVVEA
                     CGNIVAELAQDPQTMEHYKQQIAVLIELLEERFQDSNPYVRTKAIQGCSKICDLSSKF
                     NKSKAKFTSLAVRSLQDRSSLVRRNSVKLLSKLLLKHPFKAIHGSQLRLSEWEEYLKG
                     SESQLNSTLKKVESQETLNDTIERSLIEEEVEQDEGQCRTELEGSFNKSAELSRIENE
                     VENINATNTSVLMKLKLMIVYYKDAISFIKEIHKSIELISNLLFSKNRNEVLESMDFL
                     VLADAFDIELSEFGIKKMLHLVWMKGTNDEGTSISVHLIECYKQLFLTAPDSCNMQEK
                     AAHIAKNLINLSIGASIADLASLEQLLGMMYEQKLIDQHVINILWAIYNSASKASMQK
                     EQNVNNRDSEKGFSKEQIHGSIIILGMLSLADNEIALKGLESLLNIGLGAVGLKDLTL
                     CRYSCLALERMVPKRSTIITKAINQELEDVAVKKLYAIIINYTKDNEYYPMCEQALSA
                     LFTISSKPDILATDLIREKTMMTFGKPEEEDSILSLEQSSRVVSLSQLLFIVGQVAIK
                     TLVYLEKCEAEFKKRKIEAETRNGKVKNQGADVTNTTQDNGGDKELEMIGGTNEDDFT
                     DAIQFVKENELLFGEKSILGKFCPIVEEIVSNSSRFSDPMLQRTATLCLEKLMCLSSK
                     YCEKSLPLLITVMEKSPDPTIRSNAVLGLGDMAVCFNNLVDENTDYLYRRLHDENLMV
                     QRTCLMTVTFLILAGQVKVKGQLGEMAKCLDNPDQGISDMCRLFFTELASKDNAIYNG
                     FIDIFSNLSSDDLLGKESFKKIIKFLLTFIDKERHQKQLNEKLVGRLRKCETQKQWDD
                     IAFVLNNLPYKNEDVTALLEQGFKVVSAKE"
     gene            complement(687859..687932)
                     /locus_tag="tV(AAC)L"
                     /db_xref="GeneID:850978"
     tRNA            complement(687859..687932)
                     /locus_tag="tV(AAC)L"
                     /product="tRNA-Val"
                     /note="Valine tRNA (tRNA-Val), predicted by tRNAscan-SE
                     analysis"
                     /db_xref="SGD:S000006762"
                     /db_xref="GeneID:850978"
     LTR             complement(688119..688368)
                     /note="Ty1 LTR"
                     /db_xref="SGD:S000007071"
     LTR             688369..688664
                     /note="Ty1 LTR"
                     /db_xref="SGD:S000007091"
     gene            complement(<689083..>691029)
                     /gene="PIG1"
                     /locus_tag="YLR273C"
                     /db_xref="GeneID:850979"
     mRNA            complement(<689083..>691029)
                     /gene="PIG1"
                     /locus_tag="YLR273C"
                     /product="Pig1p"
                     /transcript_id="NM_001182160.1"
                     /db_xref="GI:296146806"
                     /db_xref="GeneID:850979"
     CDS             complement(689083..691029)
                     /gene="PIG1"
                     /locus_tag="YLR273C"
                     /note="Putative targeting subunit for type-1 protein
                     phosphatase Glc7p; tethers Glc7p to Gsy2p glycogen
                     synthase; PIG1 has a paralog, GAC1, that arose from the
                     whole genome duplication"
                     /codon_start=1
                     /product="Pig1p"
                     /protein_id="NP_013375.1"
                     /db_xref="GI:6323303"
                     /db_xref="SGD:S000004263"
                     /db_xref="GeneID:850979"
                     /translation="MPYSHGKKLKPSLKLAKTISTSSFVSSTTSNSFSPLEDSTSASS
                     STSSSSSGKSVRFAAHLYTVKKFNTKLAPISISEKAASNLTRNLHNNAIPLTFPFIGG
                     EDHRYSLDILDYSDLEYDNKDVEYDNESDVEDNAMLMHDRSMFIEKEILCFGEEETFD
                     MADWKLVSNNLNPFKSDYKVDVTGLEDKIFKYLNGQNIKVHSLELSDPVSYEDICSNN
                     FGNCQIWGLIFVNNLNFEKKIEIKFTLNNWADIHYINAHYNKSVTPHVDEFKFIIDIS
                     ALKLNLISKNLIYTNFFERKTTCLLNLQFCCRYDVNGFEYRSFYDNNDYKNYEITISL
                     SAINLNRAVSNSSIFNSNLGPSKMGASNAEVTMSKNNENSKKPLRKFIKDTDYYNDSP
                     LKHKFYQSFETKAACKTEPVSQTFKAETIDCEIEPFNYFFEPPDSQTNEDMSDSSYDL
                     SLQDFNYWEFSNHGLGKALADSDILQFKNYPKPEPFSRPPIIDDTFTLNTDDRTLGSK
                     TQKLEDNLAKEWKSAKTRTTLNETPLHDDEHRTSFTYTTWNNSTDTLMKRKEERPVES
                     ASCSQLSIATIKAEEDLLYQDYINSGRESSSPEISPLNTTTSLPFFPGDNMSDSSGEY
                     EERTSLSPNKIHIFRDYFYKSPSP"
     gene            <691555..>693882
                     /gene="MCM5"
                     /locus_tag="YLR274W"
                     /gene_synonym="BOB1; CDC46"
                     /db_xref="GeneID:850980"
     mRNA            <691555..>693882
                     /gene="MCM5"
                     /locus_tag="YLR274W"
                     /gene_synonym="BOB1; CDC46"
                     /product="MCM DNA helicase complex subunit MCM5"
                     /transcript_id="NM_001182161.1"
                     /db_xref="GI:296146807"
                     /db_xref="GeneID:850980"
     CDS             691555..693882
                     /gene="MCM5"
                     /locus_tag="YLR274W"
                     /gene_synonym="BOB1; CDC46"
                     /EC_number="3.6.4.12"
                     /note="Component of the Mcm2-7 hexameric helicase complex;
                     MCM complex is important for priming origins of DNA
                     replication in G1 and becomes an active ATP-dependent
                     helicase that promotes DNA melting and elongation when
                     activated by Cdc7p-Dbf4p in S-phase"
                     /codon_start=1
                     /product="MCM DNA helicase complex subunit MCM5"
                     /protein_id="NP_013376.1"
                     /db_xref="GI:6323304"
                     /db_xref="SGD:S000004264"
                     /db_xref="GeneID:850980"
                     /translation="MSFDRPEIYSAPVLQGESPNDDDNTEIIKSFKNFILEFRLDSQF
                     IYRDQLRNNILVKNYSLTVNMEHLIGYNEDIYKKLSDEPSDIIPLFETAITQVAKRIS
                     ILSRAQSANNNDKDPENTSMDTDSLLLNSLPTFQLILNSNANQIPLRDLDSEHVSKIV
                     RLSGIIISTSVLSSRATYLSIMCRNCRHTTSITINNFNSITGNTVSLPRSCLSTIESE
                     SSMANESNIGDESTKKNCGPDPYIIIHESSKFIDQQFLKLQEIPELVPVGEMPRNLTM
                     TCDRYLTNKVIPGTRVTIVGIYSIYNSKNGAGSGRSGGGNGGSGVAIRTPYIKILGIQ
                     SDVETSSIWNSVTMFTEEEEEEFLQLSRNPKLYEILTNSIAPSIFGNEDIKKAIVCLL
                     MGGSKKILPDGMRLRGDINVLLLGDPGTAKSQLLKFVEKVSPIAVYTSGKGSSAAGLT
                     ASVQRDPMTREFYLEGGAMVLADGGVVCIDEFDKMRDEDRVAIHEAMEQQTISIAKAG
                     ITTVLNSRTSVLAAANPIYGRYDDLKSPGDNIDFQTTILSRFDMIFIVKDDHNEERDI
                     SIANHVINIHTGNANAMQNQQEENGSEISIEKMKRYITYCRLKCAPRLSPQAAEKLSS
                     NFVTIRKQLLINELESTERSSIPITIRQLEAIIRITESLAKLELSPIAQERHVDEAIR
                     LFQASTMDAASQDPIGGLNQASGTSLSEIRRFEQELKRRLPIGWSTSYQTLRREFVDT
                     HRFSQLALDKALYALEKHETIQLRHQGQNIYRSGV"
     gene            <694378..>694800
                     /gene="SMD2"
                     /locus_tag="YLR275W"
                     /db_xref="GeneID:850981"
     mRNA            join(<694378..694382,694473..>694800)
                     /gene="SMD2"
                     /locus_tag="YLR275W"
                     /product="Smd2p"
                     /transcript_id="NM_001182162.1"
                     /db_xref="GI:296146808"
                     /db_xref="GeneID:850981"
     CDS             join(694378..694382,694473..694800)
                     /gene="SMD2"
                     /locus_tag="YLR275W"
                     /note="Core Sm protein Sm D2; part of heteroheptameric
                     complex (with Smb1p, Smd1p, Smd3p, Sme1p, Smx3p, and
                     Smx2p) that is part of the spliceosomal U1, U2, U4, and U5
                     snRNPs; homolog of human Sm D2"
                     /codon_start=1
                     /product="Smd2p"
                     /protein_id="NP_013377.1"
                     /db_xref="GI:6323305"
                     /db_xref="SGD:S000004265"
                     /db_xref="GeneID:850981"
                     /translation="MSSQIIDRPKHELSRAELEELEEFEFKHGPMSLINDAMVTRTPV
                     IISLRNNHKIIARVKAFDRHCNMVLENVKELWTEKKGKNVINRERFISKLFLRGDSVI
                     VVLKTPVE"
     gene            complement(<695046..>696830)
                     /gene="DBP9"
                     /locus_tag="YLR276C"
                     /db_xref="GeneID:850982"
     mRNA            complement(<695046..>696830)
                     /gene="DBP9"
                     /locus_tag="YLR276C"
                     /product="Dbp9p"
                     /transcript_id="NM_001182163.1"
                     /db_xref="GI:296146809"
                     /db_xref="GeneID:850982"
     CDS             complement(695046..696830)
                     /gene="DBP9"
                     /locus_tag="YLR276C"
                     /EC_number="3.6.4.13"
                     /EC_number="3.6.4.12"
                     /note="DEAD-box protein required for 27S rRNA processing;
                     exhibits DNA, RNA and DNA/RNA helicase activities; ATPase
                     activity shows preference for DNA over RNA; DNA helicase
                     activity abolished by mutation in RNA-binding domain"
                     /codon_start=1
                     /product="Dbp9p"
                     /protein_id="NP_013378.1"
                     /db_xref="GI:6323306"
                     /db_xref="SGD:S000004266"
                     /db_xref="GeneID:850982"
                     /translation="MSYEKKSVEGAYIDDSTTFEAFHLDSRLLQAIKNIGFQYPTLIQ
                     SHAIPLALQQKRDIIAKAATGSGKTLAYLIPVIETILEYKKTIDNGEENGTLGIILVP
                     TRELAQQVYNVLEKLVLYCSKDIRTLNISSDMSDSVLSTLLMDQPEIIVGTPGKLLDL
                     LQTKINSISLNELKFLVVDEVDLVLTFGYQDDLNKIGEYLPLKKNLQTFLMSATLNDD
                     IQALKQKFCRSPAILKFNDEEINKNQNKLLQYYVKVSEFDKFLLCYVIFKLNLIKGKT
                     LIFVNNIDRGYRLKLVMEQFGIKSCILNSELPVNSRQHIVDQFNKNVYQLLIATDDTE
                     YIKEEDDEIEEGHNTENQEEKSLEGEPENDKKPSKKKKVQVKKDKEYGVSRGVDFKNV
                     ACVLNFDLPTTAKSYVHRVGRTARGGKTGTAISFVVPLKEFGKHKPSMLQTAKKDERI
                     LSRIIKQQSKLGLELQPYKFDQKQVEAFRYRMEDGFRAVTQVAIREARVKELKQELLA
                     SEKLKRHFEENPKELQSLRHDKELHPARVQQHLKRVPDYLLPESARGNGTKVKFVPFH
                     NAKKRHSHKKGRVSKPKNGKVDPLKNFK"
     gene            complement(<697156..>699495)
                     /gene="YSH1"
                     /locus_tag="YLR277C"
                     /gene_synonym="BRR5"
                     /db_xref="GeneID:850983"
     mRNA            complement(<697156..>699495)
                     /gene="YSH1"
                     /locus_tag="YLR277C"
                     /gene_synonym="BRR5"
                     /product="Ysh1p"
                     /transcript_id="NM_001182164.1"
                     /db_xref="GI:296146810"
                     /db_xref="GeneID:850983"
     CDS             complement(697156..699495)
                     /gene="YSH1"
                     /locus_tag="YLR277C"
                     /gene_synonym="BRR5"
                     /EC_number="3.1.27.-"
                     /note="Putative endoribonuclease; subunit of the mRNA
                     cleavage and polyadenylation specificity complex; required
                     for 3' processing, splicing, and transcriptional
                     termination of mRNAs and snoRNAs; protein abundance
                     increases in response to DNA replication stress; YSH1 has
                     a paralog, SYC1, that arose from the whole genome
                     duplication"
                     /codon_start=1
                     /product="Ysh1p"
                     /protein_id="NP_013379.1"
                     /db_xref="GI:6323307"
                     /db_xref="SGD:S000004267"
                     /db_xref="GeneID:850983"
                     /translation="MERTNTTTFKFFSLGGSNEVGRSCHILQYKGKTVMLDAGIHPAY
                     QGLASLPFYDEFDLSKVDILLISHFHLDHAASLPYVMQRTNFQGRVFMTHPTKAIYRW
                     LLRDFVRVTSIGSSSSSMGTKDEGLFSDEDLVDSFDKIETVDYHSTVDVNGIKFTAFH
                     AGHVLGAAMFQIEIAGLRVLFTGDYSREVDRHLNSAEVPPLSSNVLIVESTFGTATHE
                     PRLNRERKLTQLIHSTVMRGGRVLLPVFALGRAQEIMLILDEYWSQHADELGGGQVPI
                     FYASNLAKKCMSVFQTYVNMMNDDIRKKFRDSQTNPFIFKNISYLRNLEDFQDFGPSV
                     MLASPGMLQSGLSRDLLERWCPEDKNLVLITGYSIEGTMAKFIMLEPDTIPSINNPEI
                     TIPRRCQVEEISFAAHVDFQENLEFIEKISAPNIILVHGEANPMGRLKSALLSNFASL
                     KGTDNEVHVFNPRNCVEVDLEFQGVKVAKAVGNIVNEIYKEENVEIKEEIAAKIEPIK
                     EENEDNLDSQAEKGLVDEEEHKDIVVSGILVSDDKNFELDFLSLSDLREHHPDLSTTI
                     LRERQSVRVNCKKELIYWHILQMFGEAEVLQDDDRVTNQEPKVKEESKDNLTNTGKLI
                     LQIMGDIKLTIVNTLAVVEWTQDLMNDTVADSIIAILMNVDSAPASVKLSSHSCDDHD
                     HNNVQSNAQGKIDEVERVKQISRLFKEQFGDCFTLFLNKDEYASNKEETITGVVTIGK
                     STAKIDFNNMKILECNSNPLKGRVESLLNIGGNLVTPLC"
     gene            complement(<699999..>704024)
                     /locus_tag="YLR278C"
                     /db_xref="GeneID:850984"
     mRNA            complement(<699999..>704024)
                     /locus_tag="YLR278C"
                     /product="hypothetical protein"
                     /transcript_id="NM_001182165.1"
                     /db_xref="GI:296146811"
                     /db_xref="GeneID:850984"
     CDS             complement(699999..704024)
                     /locus_tag="YLR278C"
                     /note="Zinc-cluster protein; GFP-fusion protein localizes
                     to the nucleus; mutant shows moderate growth defect on
                     caffeine; has a prion-domain like fragment that increases
                     frequency of [URE3]; YLR278C is not an essential gene"
                     /codon_start=1
                     /product="hypothetical protein"
                     /protein_id="NP_013380.1"
                     /db_xref="GI:6323308"
                     /db_xref="SGD:S000004268"
                     /db_xref="GeneID:850984"
                     /translation="MGRPRKNVSQEKIQQLKRELELAGNRTDVLLQDKKGRSRSCLLC
                     RRRKQRCDHKLPSCTACLKAGIKCVQPSKYSSSTSNSNTNNNTPTAGTVPPTPHPVIK
                     RELQDSSIGAGAGAATSLNDMTIIKPISTSNSNVDAGDANEFRKTIKSVTTNSNPNLM
                     RQDKDQYTIFLEKKLKSLETLLDLSPGCNQYNYELSQYKKVSHLFSNNTSDYSRPNSS
                     NMVILPLPSPSNKPLENTNNNGSNVNAATNDTSASTNNINNNNAICQSASLLNDPLET
                     LDFTKCIFAKYNLKKEFLMYDPIFELNEKLSRSFLDTFFTRLQFKYPILDEQEIYTFY
                     DHYLHNKILIPPSSPATSSAAPPSNSHSYSEIEFHFLSGRMWLVFSISAYLLMTTGKY
                     KGFPPHRYFSTAIRHITKCGLHLNYVQQIELLTLLVLYIIRTDRDSLILYDIIKDVMG
                     ISKKKLHLNQWYPNDPFANKKLRLFWCVYLLERMICVAVGKPYTIKESEINLPLFNND
                     SFYTKGVHAAAPSTNDHGVQFINQSLKLRRIESQFVETLQLLKNDSRSVKQSIDQLPL
                     VRKFFEDLEVWRKSYSTLDVKNFENETLKLYYYRSVRLLIQPYLEFFAPEDRLFRECQ
                     AAAGQICQLYKIFHQKTLNGHSTPAVHTVFVAGVTLIYCMWLARNFDDQRRKKLGDAS
                     KHTRPLISASLFSTMDDLRACSVCLYVMTERSNFARTFRDTFDQLMNATVGNLIERCG
                     PDSSELIFMASSVAKRTEPKNINDEANKAISSGDTLHDSNSANAANLSNSNDKNISHN
                     GGMPPAVARIFGKGQAEEHAGFVENSQVDLAEQEKFKKKQGVLEKTSVPKSLAHLLTK
                     MDDRSRISNSSMSYTTSSSSSSSSSSSSSTLSFPSSQEKNLKINVNNDNNGMTISSVN
                     REHNNNHNNNNDNNNNNNNNNNNSNNNNNVNNNDNESNSRSTTNNSCNNGNNSQYVRN
                     NNVTMENDVERPIQDQYIVKKPTNQTEFDWQVFQQQAFLQQQLAQHNLQAYLSSLNTD
                     TMTNRSPSKSSSISTASSHSDPIPIAMTQSPTPYPQTSNMLPQQHVSRPLPQQQREQP
                     QQHITSPQRFSESNFTNQLNNGMINSNPLQSAIFSNHTSENKQLRDVEESNFSTSPLR
                     ADYGNNIISSIPASFTSNSIPVSVKQARNGSSSGDILFSNGAHDMINNISTWTNNSVL
                     DALNSKSILQTIFPQSQEPSSLSMDKQQQQHQQQNMCSENNVTANNFQQTQNDPSYNR
                     NLFMMSNQEGVQYNLDETEKNGPKTQVEANTSANLHFDNVIPTVTNADIRKKRSNWDN
                     MMTSGPVEDFWTINDDYGFLT"
     gene            complement(<704493..>704960)
                     /locus_tag="YLR281C"
                     /db_xref="GeneID:850987"
     mRNA            complement(<704493..>704960)
                     /locus_tag="YLR281C"
                     /product="hypothetical protein"
                     /transcript_id="NM_001182168.1"
                     /db_xref="GI:296146812"
                     /db_xref="GeneID:850987"
     CDS             complement(704493..704960)
                     /locus_tag="YLR281C"
                     /note="hypothetical protein; green fluorescent protein
                     (GFP)-fusion protein localizes to mitochondria; YLR281C is
                     not an essential gene"
                     /codon_start=1
                     /product="hypothetical protein"
                     /protein_id="NP_013383.1"
                     /db_xref="GI:6323311"
                     /db_xref="SGD:S000004271"
                     /db_xref="GeneID:850987"
                     /translation="MMRGASKRSISSAAVLLIKKNKLPPRPKFTPEMEAQCTEKFLHG
                     GRGPGGQKINKCNSKVQLRHEPTGIVVECQETRSREQNRKLARLKLARELAASYDTMP
                     SREEALLQWHRQQKRSQRRRSVAKYEQREEAARVEKEEREARDREMVRELFRR"
     gene            <705186..>706130
                     /locus_tag="YLR283W"
                     /db_xref="GeneID:850988"
     mRNA            <705186..>706130
                     /locus_tag="YLR283W"
                     /product="hypothetical protein"
                     /transcript_id="NM_001182170.1"
                     /db_xref="GI:296146813"
                     /db_xref="GeneID:850988"
     CDS             705186..706130
                     /locus_tag="YLR283W"
                     /note="hypothetical protein; green fluorescent protein
                     (GFP)-fusion protein localizes to mitochondria; YLR283W is
                     not an essential gene"
                     /codon_start=1
                     /product="hypothetical protein"
                     /protein_id="NP_013385.1"
                     /db_xref="GI:6323312"
                     /db_xref="SGD:S000004273"
                     /db_xref="GeneID:850988"
                     /translation="MMRLIRTLPLRCFKTRIRRQGSLLCLRCFSSYSKPLLQKSMSLK
                     NIQLSDLSSSPLSKNKEKQEKPEKENEGKHSIGLLDRFSEDFITQGNGLKPTTSQNQL
                     DTIKFYQMLRERGNFSDEQCKIIIALLLQLLNDQFYSCYNDLFLRDMELNKQSHLFSS
                     LETELKFAIQNSRDTQLNEHHLQLLKLKRELNSIHDELNEIIIDLLQKDAKLEFNNQK
                     LENTLLYRQLNLKLNDCSNKIQTKILGDIRSHIENLRWQTTRSGLLVILVLVCSIMIG
                     VSASKKERPGLQEPEEPEILAPKEDIDTTFPQDQHDID"
     gene            complement(<706198..>707040)
                     /gene="ECI1"
                     /locus_tag="YLR284C"
                     /db_xref="GeneID:850990"
     mRNA            complement(<706198..>707040)
                     /gene="ECI1"
                     /locus_tag="YLR284C"
                     /product="dodecenoyl-CoA isomerase"
                     /transcript_id="NM_001182171.1"
                     /db_xref="GI:296146814"
                     /db_xref="GeneID:850990"
     CDS             complement(706198..707040)
                     /gene="ECI1"
                     /locus_tag="YLR284C"
                     /EC_number="5.3.3.8"
                     /note="Peroxisomal delta3,delta2-enoyl-CoA isomerase;
                     hexameric protein that converts 3-hexenoyl-CoA to
                     trans-2-hexenoyl-CoA, essential for the beta-oxidation of
                     unsaturated fatty acids, oleate-induced; ECI1 has a
                     paralog, DCI1, that arose from the whole genome
                     duplication"
                     /codon_start=1
                     /product="dodecenoyl-CoA isomerase"
                     /protein_id="NP_013386.1"
                     /db_xref="GI:6323314"
                     /db_xref="SGD:S000004274"
                     /db_xref="GeneID:850990"
                     /translation="MSQEIRQNEKISYRIEGPFFIIHLMNPDNLNALEGEDYIYLGEL
                     LELADRNRDVYFTIIQSSGRFFSSGADFKGIAKAQGDDTNKYPSETSKWVSNFVARNV
                     YVTDAFIKHSKVLICCLNGPAIGLSAALVALCDIVYSINDKVYLLYPFANLGLITEGG
                     TTVSLPLKFGTNTTYECLMFNKPFKYDIMCENGFISKNFNMPSSNAEAFNAKVLEELR
                     EKVKGLYLPSCLGMKKLLKSNHIDAFNKANSVEVNESLKYWVDGEPLKRFRQLGSKQR
                     KHRL"
     gene            <707360..>708145
                     /gene="NNT1"
                     /locus_tag="YLR285W"
                     /db_xref="GeneID:850991"
     mRNA            <707360..>708145
                     /gene="NNT1"
                     /locus_tag="YLR285W"
                     /product="Nnt1p"
                     /transcript_id="NM_001182172.1"
                     /db_xref="GI:296146815"
                     /db_xref="GeneID:850991"
     CDS             707360..708145
                     /gene="NNT1"
                     /locus_tag="YLR285W"
                     /EC_number="2.1.1.1"
                     /note="S-adenosylmethionine-dependent methyltransferase;
                     has a role in rDNA silencing and in lifespan
                     determination"
                     /codon_start=1
                     /product="Nnt1p"
                     /protein_id="NP_013387.1"
                     /db_xref="GI:6323315"
                     /db_xref="SGD:S000004275"
                     /db_xref="GeneID:850991"
                     /translation="MSDIESLGEAAGLFEEPEDFLPPPPKPHFAEYQRSHITKESKSD
                     VKDIKLRLVGTSPLWGHLLWNAGIYTANHLDSHPELIKGKTVLELGAAAALPSVICAL
                     NGAQMVVSTDYPDPDLMQNIDYNIKSNVPEDFNNVSTEGYIWGNDYSPLLAHIEKIGN
                     NNGKFDLIILSDLVFNHTEHHKLLQTTKDLLAEKGQALVVFSPHRPKLLEKDLEFFEL
                     AKNEFHLVPQLIEMVNWKPMFDEDEETIEVRSRVYAYYLTHEK"
     gene            complement(<708168..>708338)
                     /locus_tag="YLR285C-A"
                     /db_xref="GeneID:1466418"
     mRNA            complement(<708168..>708338)
                     /locus_tag="YLR285C-A"
                     /product="hypothetical protein"
                     /transcript_id="NM_001184567.1"
                     /db_xref="GI:296146816"
                     /db_xref="GeneID:1466418"
     CDS             complement(708168..708338)
                     /locus_tag="YLR285C-A"
                     /note="hypothetical protein; identified by fungal homology
                     and RT-PCR"
                     /codon_start=1
                     /product="hypothetical protein"
                     /protein_id="NP_878130.1"
                     /db_xref="GI:33438842"
                     /db_xref="SGD:S000028569"
                     /db_xref="GeneID:1466418"
                     /translation="MFLRFYNRLLYIYNELFNFLRFTVFLPFCEFVPHHDLFYLIVTY
                     QRTLVYKHKNDC"
     gene            complement(<708448..>710136)
                     /gene="CTS1"
                     /locus_tag="YLR286C"
                     /gene_synonym="SCW2"
                     /db_xref="GeneID:850992"
     mRNA            complement(<708448..>710136)
                     /gene="CTS1"
                     /locus_tag="YLR286C"
                     /gene_synonym="SCW2"
                     /product="Cts1p"
                     /transcript_id="NM_001182173.1"
                     /db_xref="GI:296146817"
                     /db_xref="GeneID:850992"
     CDS             complement(708448..710136)
                     /gene="CTS1"
                     /locus_tag="YLR286C"
                     /gene_synonym="SCW2"
                     /EC_number="3.2.1.14"
                     /note="Endochitinase; required for cell separation after
                     mitosis; transcriptional activation during the G1 phase of
                     the cell cycle is mediated by transcription factor Ace2p"
                     /codon_start=1
                     /product="Cts1p"
                     /protein_id="NP_013388.1"
                     /db_xref="GI:6323316"
                     /db_xref="SGD:S000004276"
                     /db_xref="GeneID:850992"
                     /translation="MSLLYIILLFTQFLLLPTDAFDRSANTNIAVYWGQNSAGTQESL
                     ATYCESSDADIFLLSFLNQFPTLGLNFANACSDTFSDGLLHCTQIAEDIETCQSLGKK
                     VLLSLGGASGSYLFSDDSQAETFAQTLWDTFGEGTGASERPFDSAVVDGFDFDIENNN
                     EVGYSALATKLRTLFAEGTKQYYLSAAPQCPYPDASVGDLLENADIDFAFIQFYNNYC
                     SVSGQFNWDTWLTYAQTVSPNKNIKLFLGLPGSASAAGSGYISDTSLLESTIADIASS
                     SSFGGIALWDASQAFSNELNGEPYVEILKNLLTSASQTATTTVATSKTSAASTSSAST
                     SSASTSQKKTTQSTTSTQSKSKVTLSPTASSAIKTSITQTTKTLTSSTKTKSSLGTTT
                     TESTLNSVAITSMKTTLSSQITSAALVTPQTTTTSIVSSAPIQTAITSTLSPATKSSS
                     VVSLQTATTSTLSPTTTSTSSGSTSSGSTSSDSTARTLAKELNAQYAAGKLNGKSTCT
                     EGEIACSADGKFAVCDHSAWVYMECASGTTCYAYDSGDSVYTQCNFSYLESNYF"
     gene            complement(<710991..>712058)
                     /locus_tag="YLR287C"
                     /db_xref="GeneID:850993"
     mRNA            complement(<710991..>712058)
                     /locus_tag="YLR287C"
                     /product="hypothetical protein"
                     /transcript_id="NM_001182174.1"
                     /db_xref="GI:296146818"
                     /db_xref="GeneID:850993"
     CDS             complement(710991..712058)
                     /locus_tag="YLR287C"
                     /note="hypothetical protein; green fluorescent protein
                     (GFP)-fusion protein localizes to the cytoplasm; YLR287C
                     is not an essential gene"
                     /codon_start=1
                     /product="hypothetical protein"
                     /protein_id="NP_013389.1"
                     /db_xref="GI:6323317"
                     /db_xref="SGD:S000004277"
                     /db_xref="GeneID:850993"
                     /translation="MSTGSSDRKDDVKLLELLNSIDEQFLVPYKKPEDLRKISSTTKL
                     QGSTPTKELDKLASVLKAHCTKIGIVCKPGTFDNNHKVVITEIQNFSRPLFYLLSLFP
                     LFYNNKDCPKYFTDQLDESTLQLLDGLRDFIAELQERLKNDENASLDKERLTSVGKIF
                     NACDSLSNCSKAGPYGILANILKDNVAIMDDTMNEIKEWLEEPDFSANSDDIFLDFED
                     SESESDSQKEEFDQEKVYENIKLFFDGFTRKIKLIKLLVSTFRKTLVSKDFTPKRNQA
                     ETLDSIHTYLKEIQLLLDEVVSTVQFEPKNFTNEEVKEEQAALVAVTKKVLIQMSKLY
                     EGDPKRKKWIDTWEIKFNELF"
     gene            complement(<712537..>713158)
                     /gene="RPS30A"
                     /locus_tag="YLR287C-A"
                     /db_xref="GeneID:850994"
     mRNA            complement(join(<712537..712725,713156..>713158))
                     /gene="RPS30A"
                     /locus_tag="YLR287C-A"
                     /product="ribosomal 40S subunit protein S30A"
                     /transcript_id="NM_001182175.1"
                     /db_xref="GI:296146819"
                     /db_xref="GeneID:850994"
     CDS             complement(join(712537..712725,713156..713158))
                     /gene="RPS30A"
                     /locus_tag="YLR287C-A"
                     /note="Protein component of the small (40S) ribosomal
                     subunit; homologous to mammalian ribosomal protein S30, no
                     bacterial homolog; RPS30A has a paralog, RPS30B, that
                     arose from the whole genome duplication"
                     /codon_start=1
                     /product="ribosomal 40S subunit protein S30A"
                     /protein_id="NP_013390.1"
                     /db_xref="GI:6323318"
                     /db_xref="SGD:S000004278"
                     /db_xref="GeneID:850994"
                     /translation="MAKVHGSLARAGKVKSQTPKVEKTEKPKKPKGRAYKRLLYTRRF
                     VNVTLVNGKRRMNPGPSVQ"
     gene            complement(<713480..>714904)
                     /gene="MEC3"
                     /locus_tag="YLR288C"
                     /gene_synonym="PIP3; PSO9"
                     /db_xref="GeneID:850995"
     mRNA            complement(<713480..>714904)
                     /gene="MEC3"
                     /locus_tag="YLR288C"
                     /gene_synonym="PIP3; PSO9"
                     /product="Mec3p"
                     /transcript_id="NM_001182176.1"
                     /db_xref="GI:296146820"
                     /db_xref="GeneID:850995"
     CDS             complement(713480..714904)
                     /gene="MEC3"
                     /locus_tag="YLR288C"
                     /gene_synonym="PIP3; PSO9"
                     /note="DNA damage and meiotic pachytene checkpoint
                     protein; subunit of a heterotrimeric complex
                     (Rad17p-Mec3p-Ddc1p) that forms a sliding clamp, loaded
                     onto partial duplex DNA by a clamp loader complex; homolog
                     of human and S. pombe Hus1"
                     /codon_start=1
                     /product="Mec3p"
                     /protein_id="NP_013391.1"
                     /db_xref="GI:6323319"
                     /db_xref="SGD:S000004279"
                     /db_xref="GeneID:850995"
                     /translation="MKLKLIVNGCEAPDDYKLLRTTINTVASLRKTAILRFNSERLTI
                     ISTPKSSLNSSNNGTILRGDTGQLWCTIPHDVFRLYTVISARELNTITMECNCDSLLS
                     VFKRYDRVMNQGSSSNMTIKLQSMPEWNTNNGTLSGGTAGGVDTTSKPNPICALGITF
                     EEIVHTSGPNDAIVMNGGVDEHNGLPTTVGTGNLLASNKVIMHSFKVPVKLLFRAQDT
                     RIQEPMINYIQLMMYKLPPISGEFGSAFHGFIRRVERYSNVNHIHLMGVKKKEHGNEG
                     DDVELKIIVNELDWHLEICWNGPLDSVIQRQEGLTDNPSQNQHIDTDGRQEEGSLPII
                     EADKPMSSLYTNTRDREMEENIRYDEDLLRIEDSSIADTRGNIYTADTSGDTEFNDIS
                     VMVEKAEQESSSTHEVIIRCKDWKVCSKLYAAFEEVVLAISHDESCVFHCSLDRGSLE
                     DSEDVEKPRERGQIIYYIARSKGL"
     gene            <715089..>717026
                     /gene="GUF1"
                     /locus_tag="YLR289W"
                     /db_xref="GeneID:850996"
     mRNA            <715089..>717026
                     /gene="GUF1"
                     /locus_tag="YLR289W"
                     /product="GTPase GUF1"
                     /transcript_id="NM_001182177.1"
                     /db_xref="GI:296146821"
                     /db_xref="GeneID:850996"
     CDS             715089..717026
                     /gene="GUF1"
                     /locus_tag="YLR289W"
                     /EC_number="3.6.5.-"
                     /note="Mitochondrial matrix GTPase; associates with
                     mitochondrial ribosomes; important for translation under
                     temperature and nutrient stress; may have a role in
                     translational fidelity; similar to bacterial LepA
                     elongation factor"
                     /codon_start=1
                     /product="GTPase GUF1"
                     /protein_id="NP_013392.1"
                     /db_xref="GI:6323320"
                     /db_xref="SGD:S000004280"
                     /db_xref="GeneID:850996"
                     /translation="MLKFRIRPVRHIRCYKRHAYFLRYNHTTTPAQKLQAQIEQIPLE
                     NYRNFSIVAHVDHGKSTLSDRLLEITHVIDPNARNKQVLDKLEVERERGITIKAQTCS
                     MFYKDKRTGKNYLLHLIDTPGHVDFRGEVSRSYASCGGAILLVDASQGIQAQTVANFY
                     LAFSLGLKLIPVINKIDLNFTDVKQVKDQIVNNFELPEEDIIGVSAKTGLNVEELLLP
                     AIIDRIPPPTGRPDKPFRALLVDSWYDAYLGAVLLVNIVDGSVRKNDKVICAQTKEKY
                     EVKDIGIMYPDRTSTGTLKTGQVGYLVLGMKDSKEAKIGDTIMHLSKVNETEVLPGFE
                     EQKPMVFVGAFPADGIEFKAMDDDMSRLVLNDRSVTLERETSNALGQGWRLGFLGSLH
                     ASVFRERLEKEYGSKLIITQPTVPYLVEFTDGKKKLITNPDEFPDGATKRVNVAAFHE
                     PFIEAVMTLPQEYLGSVIRLCDSNRGEQIDITYLNTNGQVMLKYYLPLSHLVDDFFGK
                     LKSVSRGFASLDYEDAGYRISDVVKLQLLVNGNAIDALSRVLHKSEVERVGREWVKKF
                     KEYVKSQLYEVVIQARANNKIIARETIKARRKDVLQKLHASDVSRRKKLLAKQKEGKK
                     HMKTVGNIQINQEAYQAFLRR"
     gene            complement(<717145..>717978)
                     /locus_tag="YLR290C"
                     /db_xref="GeneID:850997"
     mRNA            complement(<717145..>717978)
                     /locus_tag="YLR290C"
                     /product="hypothetical protein"
                     /transcript_id="NM_001182178.1"
                     /db_xref="GI:296146822"
                     /db_xref="GeneID:850997"
     CDS             complement(717145..717978)
                     /locus_tag="YLR290C"
                     /note="hypothetical protein; the authentic, non-tagged
                     protein is detected in highly purified mitochondria in
                     high-throughput studies; YLR290C is not an essential gene"
                     /codon_start=1
                     /product="hypothetical protein"
                     /protein_id="NP_013393.1"
                     /db_xref="GI:6323321"
                     /db_xref="SGD:S000004281"
                     /db_xref="GeneID:850997"
                     /translation="MIPKLIVFGGNGFLGKRICQEAVTSGYQVVSVSRSGKAPHSNEL
                     NDKQWMQEVQWTAADIFKPDSYHELLNNATNVVHSLGILLENENYKQTLSKSPTYDSK
                     SRLLSFGAGPNPLKKSSPYFTYEMMNKQSAIILADTFKQKILKKSKKEQEKANQRSFT
                     YISADKGFPLIPSGYINSKREAEIELEKMQRYFRPIIVRPGFMFDEHRNAIGPRSFIH
                     TALELLYCGNKFLLRNKLQLLNDLIRPTVSTQQVSKSVLKNIENPDFKGVVTLEEILK
                     A"
     gene            complement(<718317..>719462)
                     /gene="GCD7"
                     /locus_tag="YLR291C"
                     /db_xref="GeneID:850998"
     mRNA            complement(<718317..>719462)
                     /gene="GCD7"
                     /locus_tag="YLR291C"
                     /product="translation initiation factor eIF2B subunit
                     beta"
                     /transcript_id="NM_001182179.1"
                     /db_xref="GI:296146823"
                     /db_xref="GeneID:850998"
     CDS             complement(718317..719462)
                     /gene="GCD7"
                     /locus_tag="YLR291C"
                     /note="Beta subunit of the translation initiation factor
                     eIF2B; the guanine-nucleotide exchange factor for eIF2;
                     activity subsequently regulated by phosphorylated eIF2;
                     first identified as a negative regulator of GCN4
                     expression"
                     /codon_start=1
                     /product="translation initiation factor eIF2B subunit
                     beta"
                     /protein_id="NP_013394.1"
                     /db_xref="GI:6323322"
                     /db_xref="SGD:S000004282"
                     /db_xref="GeneID:850998"
                     /translation="MSSQAFTSVHPNAATSDVNVTIDTFVAKLKRRQVQGSYAIALET
                     LQLLMRFISAARWNHVNDLIEQIRDLGNSLEKAHPTAFSCGNVIRRILAVLRDEVEED
                     TMSTTVTSTSVAEPLISSMFNLLQKPEQPHQNRKNSSGSSSMKTKTDYRQVAIQGIKD
                     LIDEIKNIDEGIQQIAIDLIHDHEILLTPTPDSKTVLKFLITARERSNRTFTVLVTEG
                     FPNNTKNAHEFAKKLAQHNIETLVVPDSAVFALMSRVGKVIIGTKAVFVNGGTISSNS
                     GVSSVCECAREFRTPVFAVAGLYKLSPLYPFDVEKFVEFGGSQRILPRMDPRKRLDTV
                     NQITDYVPPENIDIYITNVGGFNPSFIYRIAWDNYKQIDVHLDKNKA"
     gene            complement(<719789..>720370)
                     /gene="SEC72"
                     /locus_tag="YLR292C"
                     /gene_synonym="SEC67; SIM2"
                     /db_xref="GeneID:850999"
     mRNA            complement(<719789..>720370)
                     /gene="SEC72"
                     /locus_tag="YLR292C"
                     /gene_synonym="SEC67; SIM2"
                     /product="Sec72p"
                     /transcript_id="NM_001182180.1"
                     /db_xref="GI:296146824"
                     /db_xref="GeneID:850999"
     CDS             complement(719789..720370)
                     /gene="SEC72"
                     /locus_tag="YLR292C"
                     /gene_synonym="SEC67; SIM2"
                     /note="Non-essential subunit of Sec63 complex; with Sec61
                     complex, Kar2p/BiP and Lhs1p forms a channel competent for
                     SRP-dependent and post-translational SRP-independent
                     protein targeting and import into the ER; other members
                     are Sec63p, Sec62p, and Sec66p"
                     /codon_start=1
                     /product="Sec72p"
                     /protein_id="NP_013395.1"
                     /db_xref="GI:6323323"
                     /db_xref="SGD:S000004283"
                     /db_xref="GeneID:850999"
                     /translation="MVTLEYNANSKLITASDAVVALSTETNIDQINVLTTSLIGETNP
                     NFTPQPNEALSKMIKGLFESGMKNLQQKKLNEALKNVSLAIEMAQRKRAPWEAFAIQL
                     PELHFMLRSKIDLCLILGKHLEALQDLDFLLGTGLIQPDVFVRKADCLLKLRQWEEAR
                     ATCERGLALAPEDMKLRALLIETARNLAEYNGE"
     gene            complement(<720771..>721430)
                     /gene="GSP1"
                     /locus_tag="YLR293C"
                     /gene_synonym="CNR1; CST17"
                     /db_xref="GeneID:851000"
     mRNA            complement(<720771..>721430)
                     /gene="GSP1"
                     /locus_tag="YLR293C"
                     /gene_synonym="CNR1; CST17"
                     /product="Ran GTPase GSP1"
                     /transcript_id="NM_001182181.1"
                     /db_xref="GI:296146825"
                     /db_xref="GeneID:851000"
     CDS             complement(720771..721430)
                     /gene="GSP1"
                     /locus_tag="YLR293C"
                     /gene_synonym="CNR1; CST17"
                     /note="Ran GTPase; GTP binding protein (mammalian Ranp
                     homolog) involved in the maintenance of nuclear
                     organization, RNA processing and transport; regulated by
                     Srm1p, Rna1p, Yrb1p, Yrb2p, Yrp4p, Yrb30p, Cse1p and
                     Kap95p; GSP1 has a paralog, GSP2, that arose from the
                     whole genome duplication"
                     /codon_start=1
                     /product="Ran GTPase GSP1"
                     /protein_id="NP_013396.1"
                     /db_xref="GI:6323324"
                     /db_xref="SGD:S000004284"
                     /db_xref="GeneID:851000"
                     /translation="MSAPAANGEVPTFKLVLVGDGGTGKTTFVKRHLTGEFEKKYIAT
                     IGVEVHPLSFYTNFGEIKFDVWDTAGQEKFGGLRDGYYINAQCAIIMFDVTSRITYKN
                     VPNWHRDLVRVCENIPIVLCGNKVDVKERKVKAKTITFHRKKNLQYYDISAKSNYNFE
                     KPFLWLARKLAGNPQLEFVASPALAPPEVQVDEQLMQQYQQEMEQATALPLPDEDDAD
                     L"
     rep_origin      720784..721418
                     /note="ARS1221;
                     Putative replication origin; identified in multiple array
                     studies, not yet confirmed by plasmid-based assay"
                     /db_xref="SGD:S000130184"
     gene            complement(<721999..>722373)
                     /gene="ATP14"
                     /locus_tag="YLR295C"
                     /db_xref="GeneID:851002"
     mRNA            complement(<721999..>722373)
                     /gene="ATP14"
                     /locus_tag="YLR295C"
                     /product="F1F0 ATP synthase subunit h"
                     /transcript_id="NM_001182183.1"
                     /db_xref="GI:296146826"
                     /db_xref="GeneID:851002"
     CDS             complement(721999..722373)
                     /gene="ATP14"
                     /locus_tag="YLR295C"
                     /EC_number="3.6.3.14"
                     /note="Subunit h of the F0 sector of mitochondrial F1F0
                     ATP synthase; F1F0 ATP synthase is a large, evolutionarily
                     conserved enzyme complex required for ATP synthesis;
                     protein abundance increases in response to DNA replication
                     stress"
                     /codon_start=1
                     /product="F1F0 ATP synthase subunit h"
                     /protein_id="NP_013398.1"
                     /db_xref="GI:6323326"
                     /db_xref="SGD:S000004286"
                     /db_xref="GeneID:851002"
                     /translation="MFPIASRRILLNASVLPLRLCNRNFTTTRISYNVIQDLYLRELK
                     DTKLAPSTLQDAEGNVKPWNPPQKPNLPELELQGPEALKAYTEQNVETAHVAKESEEG
                     ESEPIEEDWLVLDDAEETKESH"
     gene            <724044..>724433
                     /locus_tag="YLR297W"
                     /db_xref="GeneID:851004"
     mRNA            <724044..>724433
                     /locus_tag="YLR297W"
                     /product="hypothetical protein"
                     /transcript_id="NM_001182185.1"
                     /db_xref="GI:296146827"
                     /db_xref="GeneID:851004"
     CDS             724044..724433
                     /locus_tag="YLR297W"
                     /note="hypothetical protein; green fluorescent protein
                     (GFP)-fusion protein localizes to the vacuole; not an
                     essential gene; induced by treatment with
                     8-methoxypsoralen and UVA irradiation; relocalizes from
                     nucleus to vacuole upon DNA replication stress; YLR297W
                     has a paralog, YOR186W, that arose from the whole genome
                     duplication"
                     /codon_start=1
                     /product="hypothetical protein"
                     /protein_id="NP_013400.1"
                     /db_xref="GI:6323328"
                     /db_xref="SGD:S000004288"
                     /db_xref="GeneID:851004"
                     /translation="MVEGDFVDEQSNIALLSSKSMCGDHHSVKNSIGDEIFKLLTKIL
                     NSDEKASGDVHTLVSGTPDLSNFNLDNEPLENILAVFIISFIIVVVGVLLLGLIGMIF
                     ISLRSGSSNDKKLQSNDEEKQALAEKA"
     gene            complement(<724721..>725416)
                     /gene="YHC1"
                     /locus_tag="YLR298C"
                     /db_xref="GeneID:851005"
     mRNA            complement(<724721..>725416)
                     /gene="YHC1"
                     /locus_tag="YLR298C"
                     /product="Yhc1p"
                     /transcript_id="NM_001182186.1"
                     /db_xref="GI:296146828"
                     /db_xref="GeneID:851005"
     CDS             complement(724721..725416)
                     /gene="YHC1"
                     /locus_tag="YLR298C"
                     /note="Component of the U1 snRNP complex required for
                     pre-mRNA splicing; putative ortholog of human U1C protein,
                     which is involved in formation of a complex between U1
                     snRNP and the pre-mRNA 5' splice site"
                     /codon_start=1
                     /product="Yhc1p"
                     /protein_id="NP_013401.1"
                     /db_xref="GI:6323329"
                     /db_xref="SGD:S000004289"
                     /db_xref="GeneID:851005"
                     /translation="MTRYYCEYCHSYLTHDTLSVRKSHLVGKNHLRITADYYRNKARD
                     IINKHNHKRRHIGKRGRKERENSSQNETLKVTCLSNKEKRHIMHVKKMNQKELAQTSI
                     DTLKLLYDGSPGYSKVFVDANRFDIGDLVKASKLPQRANEKSAHHSFKQTSRSRDETC
                     ESNPFPRLNNPKKLEPPKILSQWSNTIPKTSIFYSVDILQTTIKESKKRMHSDGIRKP
                     SSANGYKRRRYGN"
     gene            <726069..>728051
                     /gene="ECM38"
                     /locus_tag="YLR299W"
                     /gene_synonym="CIS2"
                     /db_xref="GeneID:851006"
     mRNA            <726069..>728051
                     /gene="ECM38"
                     /locus_tag="YLR299W"
                     /gene_synonym="CIS2"
                     /product="gamma-glutamyltransferase"
                     /transcript_id="NM_001182187.1"
                     /db_xref="GI:296146829"
                     /db_xref="GeneID:851006"
     CDS             726069..728051
                     /gene="ECM38"
                     /locus_tag="YLR299W"
                     /gene_synonym="CIS2"
                     /EC_number="3.4.19.13"
                     /EC_number="2.3.2.2"
                     /note="Gamma-glutamyltranspeptidase; major
                     glutathione-degrading enzyme; involved in detoxification
                     of electrophilic xenobiotics; expression induced mainly by
                     nitrogen starvation"
                     /codon_start=1
                     /product="gamma-glutamyltransferase"
                     /protein_id="NP_013402.1"
                     /db_xref="GI:6323330"
                     /db_xref="SGD:S000004290"
                     /db_xref="GeneID:851006"
                     /translation="MLLCNRKVPKTLNTCFILHIFTLLTLGVLVSGMPSKMVSFASQE
                     TLQRINNLLRGSANRDVDIIAEYLKKDDDDDGGDKDHHNIDIDPLPRRPSLTPDRQLL
                     KVGLHGAISSDLEVCSNLTINEVLLKFPGSNAADAAVTQALCKGMVNFFNSGIGGGGY
                     VVFSGKDDEDHLSIDFREKAPMDSHKFMFENCSLCSKIGGLAVGVPGELMGLYRLFKE
                     RGSGQVDWRDLIEPVAKLGSVGWQIGEALGATLELYEDVFLTLKEDWSFVLNSTHDGV
                     LKEGDWIKRPALSNMLMELAKNGSVAPFYDPDHWIAKSMIDTVAKYNGIMNLQDVSSY
                     DVHVTKPLSMKIRKGANFIPDNDMTVLTSSGSSSGAALLAALRIMDNFQNQEGGDYEK
                     ETTYHLLESMKWMASARSRLGDFEGEALPKHIEEVLDPEWALKAVKSIKRNSQDGNFK
                     TLENWTLYDPAYDINNPHGTAHFSIVDSHGNAVSLTTTINLLFGSLVHDPKTGVIFNN
                     EMDDFAQFNKSNSFELAPSIYNFPEPGKRPLSSTAPTIVLSELGIPDLVVGASGGSRI
                     TTSVLQTIVRTYWYNMPILETIAYPRIHHQLLPDRIELESFPMIGKAVLSTLKEMGYT
                     MKEVFPKSVVNAIRNVRGEWHAVSDYWRKRGISSVY"
     gene            <728955..>730301
                     /gene="EXG1"
                     /locus_tag="YLR300W"
                     /gene_synonym="BGL1; SCW6"
                     /db_xref="GeneID:851007"
     mRNA            <728955..>730301
                     /gene="EXG1"
                     /locus_tag="YLR300W"
                     /gene_synonym="BGL1; SCW6"
                     /product="Exg1p"
                     /transcript_id="NM_001182188.1"
                     /db_xref="GI:296146830"
                     /db_xref="GeneID:851007"
     CDS             728955..730301
                     /gene="EXG1"
                     /locus_tag="YLR300W"
                     /gene_synonym="BGL1; SCW6"
                     /EC_number="3.2.1.58"
                     /note="Major exo-1,3-beta-glucanase of the cell wall;
                     involved in cell wall beta-glucan assembly; exists as
                     three differentially glycosylated isoenzymes; EXG1 has a
                     paralog, SPR1, that arose from the whole genome
                     duplication"
                     /codon_start=1
                     /product="Exg1p"
                     /protein_id="NP_013403.1"
                     /db_xref="GI:6323331"
                     /db_xref="SGD:S000004291"
                     /db_xref="GeneID:851007"
                     /translation="MLSLKTLLCTLLTVSSVLATPVPARDPSSIQFVHEENKKRYYDY
                     DHGSLGEPIRGVNIGGWLLLEPYITPSLFEAFRTNDDNDEGIPVDEYHFCQYLGKDLA
                     KSRLQSHWSTFYQEQDFANIASQGFNLVRIPIGYWAFQTLDDDPYVSGLQESYLDQAI
                     GWARNNSLKVWVDLHGAAGSQNGFDNSGLRDSYKFLEDSNLAVTTNVLNYILKKYSAE
                     EYLDTVIGIELINEPLGPVLDMDKMKNDYLAPAYEYLRNNIKSDQVIIIHDAFQPYNY
                     WDDFMTENDGYWGVTIDHHHYQVFASDQLERSIDEHIKVACEWGTGVLNESHWTVCGE
                     FAAALTDCTKWLNSVGFGARYDGSWVNGDQTSSYIGSCANNDDIAYWSDERKENTRRY
                     VEAQLDAFEMRGGWIIWCYKTESSLEWDAQRLMFNGLFPQPLTDRKYPNQCGTISN"
     gene            <730825..>731559
                     /gene="HRI1"
                     /locus_tag="YLR301W"
                     /db_xref="GeneID:851008"
     mRNA            <730825..>731559
                     /gene="HRI1"
                     /locus_tag="YLR301W"
                     /product="Hri1p"
                     /transcript_id="NM_001182189.1"
                     /db_xref="GI:296146831"
                     /db_xref="GeneID:851008"
     CDS             730825..731559
                     /gene="HRI1"
                     /locus_tag="YLR301W"
                     /note="hypothetical protein that interacts with Sec72p and
                     Hrr25p"
                     /codon_start=1
                     /product="Hri1p"
                     /protein_id="NP_013404.1"
                     /db_xref="GI:6323332"
                     /db_xref="SGD:S000004292"
                     /db_xref="GeneID:851008"
                     /translation="MPALLKRLLFQVGPHPNERTFTLSSVSTDGHYISLRPFVKPSGD
                     ELSFPFEWAFAGTNETVKANDQGNGVVTQDFNFWLDTNVYLNVPNTHRGEVNTTWKNW
                     DSGCVEETGAVYPFGADKESVSFRELWQPVDPSREDLVIVSPNNEKFSSNARSIVLKV
                     TDEAYDGLVIVIGRWIQGFLSQKNNNTIEGLNFIRLLEKDSGKSEFLLSYGKEVNKIP
                     QSYENLKKGSTVTSNGLNWEVIEYHA"
     LTR             complement(731668..732000)
                     /note="Ty2 LTR"
                     /db_xref="SGD:S000007072"
     gene            732090..732190
                     /locus_tag="tL(UAG)L2"
                     /db_xref="GeneID:851009"
     tRNA            join(732090..732127,732147..732190)
                     /locus_tag="tL(UAG)L2"
                     /product="tRNA-Leu"
                     /note="Leucine tRNA (tRNA-Leu), predicted by tRNAscan-SE
                     analysis"
                     /db_xref="SGD:S000006656"
                     /db_xref="GeneID:851009"
     gene            <732542..>733876
                     /gene="MET17"
                     /locus_tag="YLR303W"
                     /gene_synonym="MET15; MET25"
                     /db_xref="GeneID:851010"
     mRNA            <732542..>733876
                     /gene="MET17"
                     /locus_tag="YLR303W"
                     /gene_synonym="MET15; MET25"
                     /product="bifunctional cysteine
                     synthase/O-acetylhomoserine aminocarboxypropyltransferase
                     MET17"
                     /transcript_id="NM_001182191.1"
                     /db_xref="GI:296146832"
                     /db_xref="GeneID:851010"
     CDS             732542..733876
                     /gene="MET17"
                     /locus_tag="YLR303W"
                     /gene_synonym="MET15; MET25"
                     /EC_number="2.5.1.49"
                     /EC_number="2.5.1.47"
                     /note="O-acetyl homoserine-O-acetyl serine sulfhydrylase;
                     required for Methionine and cysteine biosynthesis"
                     /codon_start=1
                     /product="bifunctional cysteine
                     synthase/O-acetylhomoserine aminocarboxypropyltransferase
                     MET17"
                     /protein_id="NP_013406.1"
                     /db_xref="GI:6323333"
                     /db_xref="SGD:S000004294"
                     /db_xref="GeneID:851010"
                     /translation="MPSHFDTVQLHAGQENPGDNAHRSRAVPIYATTSYVFENSKHGS
                     QLFGLEVPGYVYSRFQNPTSNVLEERIAALEGGAAALAVSSGQAAQTLAIQGLAHTGD
                     NIVSTSYLYGGTYNQFKISFKRFGIEARFVEGDNPEEFEKVFDERTKAVYLETIGNPK
                     YNVPDFEKIVAIAHKHGIPVVVDNTFGAGGYFCQPIKYGADIVTHSATKWIGGHGTTI
                     GGIIVDSGKFPWKDYPEKFPQFSQPAEGYHGTIYNEAYGNLAYIVHVRTELLRDLGPL
                     MNPFASFLLLQGVETLSLRAERHGENALKLAKWLEQSPYVSWVSYPGLASHSHHENAK
                     KYLSNGFGGVLSFGVKDLPNADKETDPFKLSGAQVVDNLKLASNLANVGDAKTLVIAP
                     YFTTHKQLNDKEKLASGVTKDLIRVSVGIEFIDDIIADFQQSFETVFAGQKP"
     LTR             complement(734501..734671)
                     /note="Ty1 LTR"
                     /db_xref="SGD:S000007073"
     gene            734802..734875
                     /locus_tag="tI(AAU)L1"
                     /db_xref="GeneID:851012"
     tRNA            734802..734875
                     /locus_tag="tI(AAU)L1"
                     /product="tRNA-Ile"
                     /note="Isoleucine tRNA (tRNA-Ile), predicted by
                     tRNAscan-SE analysis"
                     /db_xref="SGD:S000006607"
                     /db_xref="GeneID:851012"
     gene            complement(<735212..>737548)
                     /gene="ACO1"
                     /locus_tag="YLR304C"
                     /gene_synonym="GLU1"
                     /db_xref="GeneID:851013"
     mRNA            complement(<735212..>737548)
                     /gene="ACO1"
                     /locus_tag="YLR304C"
                     /gene_synonym="GLU1"
                     /product="aconitate hydratase ACO1"
                     /transcript_id="NM_001182192.1"
                     /db_xref="GI:296146833"
                     /db_xref="GeneID:851013"
     CDS             complement(735212..737548)
                     /gene="ACO1"
                     /locus_tag="YLR304C"
                     /gene_synonym="GLU1"
                     /EC_number="4.2.1.3"
                     /note="Aconitase; required for the tricarboxylic acid
                     (TCA) cycle and also independently required for
                     mitochondrial genome maintenance; phosphorylated;
                     component of the mitochondrial nucleoid; mutation leads to
                     glutamate auxotrophy"
                     /codon_start=1
                     /product="aconitate hydratase ACO1"
                     /protein_id="NP_013407.1"
                     /db_xref="GI:6323335"
                     /db_xref="SGD:S000004295"
                     /db_xref="GeneID:851013"
                     /translation="MLSARSAIKRPIVRGLATVSNLTRDSKVNQNLLEDHSFINYKQN
                     VETLDIVRKRLNRPFTYAEKILYGHLDDPHGQDIQRGVSYLKLRPDRVACQDATAQMA
                     ILQFMSAGLPQVAKPVTVHCDHLIQAQVGGEKDLKRAIDLNKEVYDFLASATAKYNMG
                     FWKPGSGIIHQIVLENYAFPGALIIGTDSHTPNAGGLGQLAIGVGGADAVDVMAGRPW
                     ELKAPKILGVKLTGKMNGWTSPKDIILKLAGITTVKGGTGKIVEYFGDGVDTFSATGM
                     GTICNMGAEIGATTSVFPFNKSMIEYLEATGRGKIADFAKLYHKDLLSADKDAEYDEV
                     VEIDLNTLEPYINGPFTPDLATPVSKMKEVAVANNWPLDVRVGLIGSCTNSSYEDMSR
                     SASIVKDAAAHGLKSKTIFTVTPGSEQIRATIERDGQLETFKEFGGIVLANACGPCIG
                     QWDRRDIKKGDKNTIVSSYNRNFTSRNDGNPQTHAFVASPELVTAFAIAGDLRFNPLT
                     DKLKDKDGNEFMLKPPHGDGLPQRGYDAGENTYQAPPADRSTVEVKVSPTSDRLQLLK
                     PFKPWDGKDAKDMPILIKAVGKTTTDHISMAGPWLKYRGHLENISNNYMIGAINAENK
                     KANCVKNVYTGEYKGVPDTARDYRDQGIKWVVIGDENFGEGSSREHAALEPRFLGGFA
                     IITKSFARIHETNLKKQGLLPLNFKNPADYDKINPDDRIDILGLAELAPGKPVTMRVH
                     PKNGKPWDAVLTHTFNDEQIEWFKYGSALNKIKADEKK"
     gene            complement(<738161..>743863)
                     /gene="STT4"
                     /locus_tag="YLR305C"
                     /db_xref="GeneID:851014"
     mRNA            complement(<738161..>743863)
                     /gene="STT4"
                     /locus_tag="YLR305C"
                     /product="1-phosphatidylinositol 4-kinase STT4"
                     /transcript_id="NM_001182193.1"
                     /db_xref="GI:296146834"
                     /db_xref="GeneID:851014"
     CDS             complement(738161..743863)
                     /gene="STT4"
                     /locus_tag="YLR305C"
                     /EC_number="2.7.1.67"
                     /note="Phosphatidylinositol-4-kinase; functions in the
                     Pkc1p protein kinase pathway; required for normal vacuole
                     morphology, cell wall integrity, and actin cytoskeleton
                     organization"
                     /codon_start=1
                     /product="1-phosphatidylinositol 4-kinase STT4"
                     /protein_id="NP_013408.1"
                     /db_xref="GI:6323336"
                     /db_xref="SGD:S000004296"
                     /db_xref="GeneID:851014"
                     /translation="MRFTRGLKASSSLRAKAIGRLTKLSTGAPNDQNSNGTTLDLITH
                     TLPIFYSTNTSKIYTIPLTLSEWEVLTSLCVAIPTTLDLVETMLKEIIAPYFLETPRQ
                     RISDVLSSKFKLEQMRNPIELLTFQLTKFMIQACEQYPVLYENIGGIISTYFERVLKI
                     FTIKQSGLLSLVGFINAFIQFPNSTELTKFTWKKLAKLVLRGSFLNEVDKILNSSATF
                     TNDSIVQYYDAGNELSSAYLLELISRLQVSLISHLLNTSHVGANLSEFLLNQQYQFYK
                     FDQEVADENDDTKCIDDFFFNVRSNKQFFTDMCKISLQFCSESHILDLSTDNRARFSF
                     DTRAHYLQTLCLIPFIEDTESELFESFTNVVSESIDKFFLSDVVTPSLIKAIVASASL
                     LNFFTEKLSLTLIRMFPLLVASPHITTETVNDVAKIFTTGLYPLNEDAIVSTIYSMNN
                     LLAVSEDGSPVPVLRERQLTITSGKNIEKDYFPLRNSSASLDGTGALLGNTTVGQLSS
                     HDVNSGATMTYHASLISNCVAATTTIASYYNTQSITALTISILTQKVNSMSKELDGVI
                     LNSLARLAPNTSLTEFSLLLKFFKSRTVIATKIDDSALLKNIIKAKCVISKELLARHF
                     SSDLYFMYLHDLLDSIIASGEVERLEHHRPQTEISRVADQIATYLEPLAALLPVPGDT
                     PLDINKDEVTTNKFRNAWFNFVIHGYHLGGPIVKRNFSFLLTIAYNSPPLASEFPANN
                     KELSLEMNTILRRGSSNENIKQQKQQITEYFNTNIVQYRTTSSSKIMFLAAAVLLETI
                     RCEAGDCSKTLLYFSDPSILSGSIEKCIAVLSVSMIRKYARLIQKGNDAIFNSKMIAQ
                     QLNNLLLCLSHREPTLQDAAFHACEIFIRSIPSSLCHHLSLYTLLDMLTALFDSILDS
                     EAHKFEPRYEFKLKHSKTTILVPSSSSWRATTLSRLHKSAKEWVRILLNRSNQDTKIL
                     LQSYISDLGEYSRLNSVEFGVSFAMDMAGLILPADKELSRLTYYGPEKPNTISGFISL
                     HSWRSKYLFDTAITSSPEDIKRQIGISTQNIRKNLTLGNKIITKDVTDFLDMATALLI
                     LGNGAPASLIYDIVHIPFEVFTSASLKIATNVWLTIITEKPEVAHLLLVEVCYCWMRS
                     IDDNIGLYSRDHDLKGEEYQKMEYSPYDKAGINRDAKNASQAMQPHLHVIKFFASHFE
                     GTLFQSDFLLKIFTKCALYGIKNLYKASLHPFARMIRHELLLFATLVLNASYKQGSKY
                     MGRLSQEITNGALSWFKRPVAWPFGSNELKIKADLSVTRDLFLQLNKLSSLMSRHCGK
                     DYKILNYFLASEIQQIQTWLTPTEKIEGADSNELTSDIVEATFAKDPTLAINLLQRCY
                     SKKAEDVLVGLVAKHALMCVGSPSALDLFIKGSHLSSKKDLHATLYWAPVSPLKSINL
                     FLPEWQGNSFILQFSIYSLESQDVNLAFFYVPQIVQCLRYDKTGYVERLILDTAKISV
                     LFSHQIIWNMLANCYKDDEGIQEDEIKPTLDRIRERMVSSFSQSHRDFYEREFEFFDE
                     VTGISGKLKPYIKKSKAEKKHKIDEEMSKIEVKPDVYLPSNPDGVVIDIDRKSGKPLQ
                     SHAKAPFMATFKIKKDVKDPLTGKNKEVEKWQAAIFKVGDDCRQDVLALQLISLFRTI
                     WSSIGLDVYVFPYRVTATAPGCGVIDVLPNSVSRDMLGREAVNGLYEYFTSKFGNEST
                     IEFQNARNNFVKSLAGYSVISYLLQFKDRHNGNIMYDDQGHCLHIDFGFIFDIVPGGI
                     KFEAVPFKLTKEMVKVMGGSPQTPAYLDFEELCIKAYLAARPHVEAIIECVNPMLGSG
                     LPCFKGHKTIRNLRARFQPQKTDHEAALYMKALIRKSYESIFTKGYDEFQRLTNGIPY
                     "
     gene            <744151..>744851
                     /gene="UBC12"
                     /locus_tag="YLR306W"
                     /db_xref="GeneID:851015"
     mRNA            join(<744151..744153,744288..>744851)
                     /gene="UBC12"
                     /locus_tag="YLR306W"
                     /product="NEDD8-conjugating protein UBC12"
                     /transcript_id="NM_001182194.1"
                     /db_xref="GI:296146835"
                     /db_xref="GeneID:851015"
     CDS             join(744151..744153,744288..744851)
                     /gene="UBC12"
                     /locus_tag="YLR306W"
                     /EC_number="6.3.2.-"
                     /note="Enzyme that mediates the conjugation of Rub1p; a
                     ubiquitin-like protein, to other proteins; related to E2
                     ubiquitin-conjugating enzymes"
                     /codon_start=1
                     /product="NEDD8-conjugating protein UBC12"
                     /protein_id="NP_013409.1"
                     /db_xref="GI:6323337"
                     /db_xref="SGD:S000004297"
                     /db_xref="GeneID:851015"
                     /translation="MLKLRQLQKKKQKENENSSSIQPNLSAARIRLKRDLDSLDLPPT
                     VTLNVITSPDSADRSQSPKLEVIVRPDEGYYNYGSINFNLDFNEVYPIEPPKVVCLKK
                     IFHPNIDLKGNVCLNILREDWSPALDLQSIITGLLFLFLEPNPNDPLNKDAAKLLCEG
                     EKEFAEAVRLTMSGGSIEHVKYDNIVSP"
     rep_origin      744943..745179
                     /note="ARS1223;
                     Autonomously Replicating Sequence; replication capacity
                     dependent upon Sum1p"
                     /db_xref="SGD:S000118479"
     gene            <745620..>746525
                     /gene="CDA1"
                     /locus_tag="YLR307W"
                     /db_xref="GeneID:851016"
     mRNA            <745620..>746525
                     /gene="CDA1"
                     /locus_tag="YLR307W"
                     /product="chitin deacetylase CDA1"
                     /transcript_id="NM_001182195.1"
                     /db_xref="GI:296146836"
                     /db_xref="GeneID:851016"
     CDS             745620..746525
                     /gene="CDA1"
                     /locus_tag="YLR307W"
                     /EC_number="3.5.1.41"
                     /note="Chitin deacetylase; together with Cda2p involved in
                     the biosynthesis ascospore wall component, chitosan;
                     required for proper rigidity of the ascospore wall"
                     /codon_start=1
                     /product="chitin deacetylase CDA1"
                     /protein_id="NP_013410.1"
                     /db_xref="GI:6323338"
                     /db_xref="SGD:S000004298"
                     /db_xref="GeneID:851016"
                     /translation="MKIFNTIQSVLFAAFFLKQGNCLASNGSTALMGEVDMQTPFPEW
                     LTEFTNLTQWPGIDPPYIPLDYINLTEVPELDRYYPGQCPKISREQCSFDCYNCIDVD
                     DVTSCFKLSQTFDDGPAPATEALLKKLRQRTTFFVLGINTVNYPDIYEHILERGHLIG
                     THTWSHEFLPSLSNEEIVAQIEWSIWAMNATGKHFPKYFRPPYGAIDNRVRAIVKQFG
                     LTVVLWDLDTFDWKLITNDDFRTEEEILMDINTWKGKRKGLILEHDGARRTVEVAIKI
                     NELIGSDQLTIAECIGDTDYIERYD"
     gene            complement(<746848..>747111)
                     /locus_tag="YLR307C-A"
                     /db_xref="GeneID:1466419"
     mRNA            complement(<746848..>747111)
                     /locus_tag="YLR307C-A"
                     /product="hypothetical protein"
                     /transcript_id="NM_001184535.1"
                     /db_xref="GI:296146837"
                     /db_xref="GeneID:1466419"
     CDS             complement(746848..747111)
                     /locus_tag="YLR307C-A"
                     /codon_start=1
                     /product="hypothetical protein"
                     /protein_id="NP_878131.1"
                     /db_xref="GI:33438843"
                     /db_xref="SGD:S000028525"
                     /db_xref="GeneID:1466419"
                     /translation="MSLRNISMITKNLQTTAKCYVPKSSPTSTTIPVIRDASTTQCRR
                     ITTVINITSLKGYSPSPRTVHDKPIVICTDNEEVETVSEHVKV"
     gene            <747937..>748875
                     /gene="CDA2"
                     /locus_tag="YLR308W"
                     /db_xref="GeneID:851017"
     mRNA            <747937..>748875
                     /gene="CDA2"
                     /locus_tag="YLR308W"
                     /product="chitin deacetylase CDA2"
                     /transcript_id="NM_001182196.1"
                     /db_xref="GI:296146838"
                     /db_xref="GeneID:851017"
     CDS             747937..748875
                     /gene="CDA2"
                     /locus_tag="YLR308W"
                     /EC_number="3.5.1.41"
                     /note="Chitin deacetylase; together with Cda1p involved in
                     the biosynthesis ascospore wall component, chitosan;
                     required for proper rigidity of the ascospore wall"
                     /codon_start=1
                     /product="chitin deacetylase CDA2"
                     /protein_id="NP_013411.1"
                     /db_xref="GI:6323339"
                     /db_xref="SGD:S000004299"
                     /db_xref="GeneID:851017"
                     /translation="MRIQLNTIDLQCIIALSCLGQFVHAEANREDLKQIDFQFPVLER
                     AATKTPFPDWLSAFTGLKEWPGLDPPYIPLDFIDFSQIPDYKEYDQNHCDSVPRDSCS
                     FDCHHCTEHDDVYTCSKLSQTFDDGPSASTTKLLDRLKHNSTFFNLGVNIVQHPDIYQ
                     RMQKEGHLIGSHTWSHVYLPNVSNEKIIAQIEWSIWAMNATGNHTPKWFRPPYGGIDN
                     RVRAITRQFGLQAVLWDHDTFDWSLLLNDSVITEQEILQNVINWNKSGTGLILEHDST
                     EKTVDLAIKINKLIGDDQSTVSHCVGGIDYIKEFLS"
     gene            complement(<749034..>751769)
                     /gene="IMH1"
                     /locus_tag="YLR309C"
                     /gene_synonym="SYS3"
                     /db_xref="GeneID:851018"
     mRNA            complement(<749034..>751769)
                     /gene="IMH1"
                     /locus_tag="YLR309C"
                     /gene_synonym="SYS3"
                     /product="Imh1p"
                     /transcript_id="NM_001182197.2"
                     /db_xref="GI:330443672"
                     /db_xref="GeneID:851018"
     CDS             complement(749034..751769)
                     /gene="IMH1"
                     /locus_tag="YLR309C"
                     /gene_synonym="SYS3"
                     /note="Protein involved in vesicular transport; mediates
                     transport between an endosomal compartment and the Golgi,
                     contains a Golgi-localization (GRIP) domain that interacts
                     with activated Arl1p-GTP to localize Imh1p to the Golgi"
                     /codon_start=1
                     /product="Imh1p"
                     /protein_id="NP_013412.1"
                     /db_xref="GI:6323340"
                     /db_xref="SGD:S000004300"
                     /db_xref="GeneID:851018"
                     /translation="MFKQLSQIGKNLTDELAKGLADDMSPTPSEQQIEDDKSGLPKEI
                     QAKLRKFEKYEQKYPLLLSAYKNEKLKSEKLEAVEKILAENTPISNIDDAVDTLPAFF
                     QDLNNKNNLLNDEIKRLTKQNSEIPESASSETLKDKEEEFLKKEQNYKNDIDDLKKKM
                     EALNIELDTVQKEKNDTVSGLREKIVALENILKEEREAKKQKEEVSISELKEELAIKN
                     HSLEDSRMKITELEQNLSSKSTIMEEKSSELAELNITLKEKERKLSELEKKMKELPKA
                     ISHQNVGNNNRRKKNRNKGKKNKGGITTGDISEEETVDNSINTEEYDKLKENLQELQE
                     KYKDCEDWKQKYEDIEAELKDAKELENSQLEKSAKELETLNTELIDTKKSLKEKNSEL
                     EEVRDMLRTVGNELVDAKDEIKESSSKQNEEVKTVKLELDDLRHKNATMIEAYEAKNT
                     ELRSKIELLSKKVEHLKNLCTEKEKEQTTSQNKVAKLNEEISQLTYEKSNITKELTSL
                     RTSYKQKEKTVSYLEEQVKQFSEQKDVAEKSTEQLRKDHAKISNRLDLLKKENETLHN
                     DIAKNSNSYEEYLKENGKLSERLNILQEKYNTLQNVKSNSNEHIDSIKRQCEELNVKL
                     KESTKKILSLEDELNEYANIVQDKTREANTLRRLVSDSQTDDSSKQKELENKLAYLTD
                     EKNKLEAELDLQTSRKATELQEWKHTVTELKSEIHALKLREEGLKSEVDALKHVNNDI
                     KRKTQATSDDSDQLEQITSNLKLSLSKADEKNFELQSANEKLLNLNNELNKKFDRLLK
                     NYRSLSSQLNALKERQYSDKSGRVSRSGSIGTLANANIDSSPANNSNPTKLEKIRSSS
                     SLELDSEKNEKIAYIKNVLLGFLEHKEQRNQLLPVISMLLQLDSTDEKRLVMSLK"
     gene            complement(<752224..>756993)
                     /gene="CDC25"
                     /locus_tag="YLR310C"
                     /gene_synonym="CTN1"
                     /db_xref="GeneID:851019"
     mRNA            complement(<752224..>756993)
                     /gene="CDC25"
                     /locus_tag="YLR310C"
                     /gene_synonym="CTN1"
                     /product="Cdc25p"
                     /transcript_id="NM_001182198.1"
                     /db_xref="GI:296146840"
                     /db_xref="GeneID:851019"
     CDS             complement(752224..756993)
                     /gene="CDC25"
                     /locus_tag="YLR310C"
                     /gene_synonym="CTN1"
                     /note="Membrane bound guanine nucleotide exchange factor;
                     indirectly regulates adenylate cyclase through activation
                     of Ras1p and Ras2p by stimulating the exchange of GDP for
                     GTP; required for progression through G1; a membrane bound
                     guanine nucleotide exchange factor is also known as a GEF
                     or GDP-release factor"
                     /codon_start=1
                     /product="Cdc25p"
                     /protein_id="NP_013413.1"
                     /db_xref="GI:6323341"
                     /db_xref="SGD:S000004301"
                     /db_xref="GeneID:851019"
                     /translation="MSDTNTSIPNTSSAREAGNASQTPSISSSSNTSTTTNTESSSAS
                     LSSSPSTSELTSIRPIGIVVAAYDFNYPIKKDSSSQLLSVQQGETIYILNKNSSGWWD
                     GLVIDDSNGKVNRGWFPQNFGRPLRDSHLRKHSHPMKKYSSSKSSRRSSLNSLGNSAY
                     LHVPRNPSKSRRGSSTLSASLSNAHNAETSSGHNNTVSMNNSPFSAPNDASHITPQSS
                     NFNSNASLSQDMTKSADGSSEMNTNAIMNNNETNLQTSGEKAGPPLVAEETIKILPLE
                     EIEMIINGIRSNIASTWSPIPLITKTSDYKLVYYNKDLDIYCSELPLISNSIMESDDI
                     CDSEPKFPPNDHLVNLYTRDLRKNANIEDSSTRSKQSESEQNRSSLLMEKQDSKETDG
                     NNNSINDDDNNNENNKNEFNEAGPSSLNSLSAPDLTQNIQSRVVAPSRSSILAKSDIF
                     YHYSRDIKLWTELQDLTVYYTKTAHKMFLKENRLNFTKYFDLISDSIVFTQLGCRLMQ
                     HEIKAKSCSKEIKKIFKGLISSLSRISINSHLYFDSAFHRKKMDTMNDKDNDNQENNC
                     SRTEGDDGKIEVDSVHDLVSVPLSGKRNVSTSTTDTLTPMRSSFSTVNENDMENFSVL
                     GPRNSVNSVVTPRTSIQNSTLEDFSPSNKNFKSAKSIYEMVDVEFSKFLRHVQLLYFV
                     LQSSVFSDDNTLPQLLPRFFKGSFSGGSWTNPFSTFITDEFGNATKNKAVTSNEVTAS
                     SSKNSSISRIPPKMADAIASASGYSANSETNSQIDLKASSAASGSVFTPFNRPSHNRT
                     FSRARVSKRKKKYPLTVDTLNTMKKKSSQIFEKLNNATGEHLKIISKPKSRIRNLEIN
                     SSTYEQINQNVLLLEILENLDLSIFINLKNLIKTPSILLDLESEEFLVHAMSSVSSVL
                     TEFFDIKQAFHDIVIRLIMTTQQTTLDDPYLFSSMRSNFPVGHHEPFKNISNTPLVKG
                     PFHKKNEQLALSLFHVLVSQDVEFNNLEFLNNSDDFKDACEKYVEISNLACIIVDQLI
                     EERENLLNYAARMMKNNLTAELLKGEQEKWFDIYSEDYSDDDSENDEAIIDDELGSED
                     YIERKAANIEKNLPWFLTSDYETSLVYDSRGKIRGGTKEALIEHLTSHELVDAAFNVT
                     MLITFRSILTTREFFYALIYRYNLYPPEGLSYDDYNIWIEKKSNPIKCRVVNIMRTFL
                     TQYWTRNYYEPGIPLILNFAKMVVSEKIPGAEDLLQKINEKLINENEKEPVDPKQQDS
                     VSAVVQTTKRDNKSPIHMSSSSLPSSASSAFFRLKKLKLLDIDPYTYATQLTVLEHDL
                     YLRITMFECLDRAWGTKYCNMGGSPNITKFIANANTLTNFVSHTIVKQADVKTRSKLT
                     QYFVTVAQHCKELNNFSSMTAIVSALYSSPIYRLKKTWDLVSTESKDLLKNLNNLMDS
                     KRNFVKYRELLRSVTDVACVPFFGVYLSDLTFTFVGNPDFLHNSTNIINFSKRTKIAN
                     IVEEIISFKRFHYKLKRLDDIQTVIEASLENVPHIEKQYQLSLQVEPRSGNTKGSTHA
                     SSASGTKTAKFLSEFTDDKNGNFLKLGKKKPPSRLFR"
     gene            complement(<757637..>758833)
                     /locus_tag="YLR312C"
                     /db_xref="GeneID:851021"
     mRNA            complement(<757637..>758833)
                     /locus_tag="YLR312C"
                     /product="hypothetical protein"
                     /transcript_id="NM_001182200.1"
                     /db_xref="GI:296146841"
                     /db_xref="GeneID:851021"
     CDS             complement(757637..758833)
                     /locus_tag="YLR312C"
                     /codon_start=1
                     /product="hypothetical protein"
                     /protein_id="NP_013415.1"
                     /db_xref="GI:6323343"
                     /db_xref="SGD:S000004303"
                     /db_xref="GeneID:851021"
                     /translation="MSEEDDHWNLVRLRRLRKGREGEEQSSKSEISLDSLHESSFAGE
                     DDEDFDADVLSNTSSEESAQMNRIYDFRTSNEFSNAGVNIDQTGVPTISESFDTLSGS
                     NVGGTVLPSMEGSKLKDSTIRNSSTLSDHIIDKSEGKSAKLKMWHVIMLSSLLSMTFS
                     YLALEYSLTGDVLAGFKSQQSLRNNERKLLYGNIDFVDKKSYDSSSDSLSQWAPSGKY
                     YVDFDNHIAYPLKDDDLMGWRRYKTDLVILWYTTKARMKDGWHKRINKINGGRIKLHL
                     FLKNSFKSAQESLRVLHKEQKRRWKRLFVLLHNKYRQFSPHIKRYFDHSCQKAKQCWS
                     GSRLQLRKLRFKSMKPFRVFQFKVRKDTNWFVKQLKRFGLKLQHSRMYKAMSECRKKN
                     YFKCKH"
     gene            <759480..>760241
                     /gene="MRPL15"
                     /locus_tag="YLR312W-A"
                     /db_xref="GeneID:851022"
     mRNA            <759480..>760241
                     /gene="MRPL15"
                     /locus_tag="YLR312W-A"
                     /product="mitochondrial 54S ribosomal protein YmL15"
                     /transcript_id="NM_001182201.1"
                     /db_xref="GI:296146842"
                     /db_xref="GeneID:851022"
     CDS             759480..760241
                     /gene="MRPL15"
                     /locus_tag="YLR312W-A"
                     /note="Mitochondrial ribosomal protein of the large
                     subunit"
                     /codon_start=1
                     /product="mitochondrial 54S ribosomal protein YmL15"
                     /protein_id="NP_013416.2"
                     /db_xref="GI:116006497"
                     /db_xref="SGD:S000004304"
                     /db_xref="GeneID:851022"
                     /translation="MENSMMFISRSLRRPVTALNCNLQSVRTVIYLHKGPRINGLRRD
                     PESYLRNPSGVLFTEVNAKECQDKVRSILQLPKYGINLSNELILQCLTHKSFAHGSKP
                     YNEKLNLLGAQFLKLQTCIHSLKNGSPAESCENGQLSLQFSNLGTKFAKELTSKNTAC
                     TFVKLHNLDPFIFWKMRDPIKDGHINGETTIFASVLNAFIGAILSTNGSEKAAKFIQG
                     SLLDKEDLHSLVNIANENVASAKAKISDKENKAFL"
     gene            complement(<760750..>762342)
                     /gene="SPH1"
                     /locus_tag="YLR313C"
                     /gene_synonym="YLR312C-B"
                     /db_xref="GeneID:851023"
     mRNA            complement(<760750..>762342)
                     /gene="SPH1"
                     /locus_tag="YLR313C"
                     /gene_synonym="YLR312C-B"
                     /product="Sph1p"
                     /transcript_id="NM_001182202.2"
                     /db_xref="GI:330443673"
                     /db_xref="GeneID:851023"
     CDS             complement(760750..762342)
                     /gene="SPH1"
                     /locus_tag="YLR313C"
                     /gene_synonym="YLR312C-B"
                     /note="Protein involved in shmoo formation and bipolar bud
                     site selection; localizes to sites of polarized growth in
                     a cell cycle dependent- and Spa2p-dependent manner,
                     interacts with MAPKKs Mkk1p, Mkk2p, and Ste7p; SPH1 has a
                     paralog, SPA2, that arose from the whole genome
                     duplication"
                     /codon_start=1
                     /product="Sph1p"
                     /protein_id="NP_013417.3"
                     /db_xref="GI:330443674"
                     /db_xref="SGD:S000004305"
                     /db_xref="GeneID:851023"
                     /translation="MISSELTNDQIIDLISDYKNFKRIIEASVPEDDRRRNQNRQNRN
                     KDLTKLSNVQFWQLTTDVNDELMKRLTDSGADASLNDLDLKRGKAQSKLSRLKDAKFH
                     KLILDIFTEIERRNLHHLDMGTHNNGLDEGDLNFYLNDTLFESFKINDDFMSVNGIIS
                     IEVFRELKTQFTLYFQNTLHRIDPVDTTTTRLPILLETIIKIAKLIGDLLPVLSSVSL
                     QSSLENEIVYLKSALSHAITSTRYFLTYGDLIPRIVAQSSISEVIFAFCNIAQIVKIK
                     STSRDDISRNEGELSDIEAGMKPLKIIEKVKNEKNGKDISSLGDSGSTAVSFPSSGKP
                     ITKKSDMPVVVASPSISIIEKSESSIRESGKVRNNTSGETNLASVSPLKNTKNSSRIT
                     SEPSPREGLPLKVVSNSRSPSPQGNTLPLIGKFRQDYQASPPKKVITKPVAETAKPYA
                     NIPPAADVLYSPTVTKMRKFREKVQKFAPNSGLGLRISTSEENLNNSDVNSTTHNANI
                     NNLVEFVESKSMVVLPMAGRAF"
     gene            complement(<762575..>764137)
                     /gene="CDC3"
                     /locus_tag="YLR314C"
                     /db_xref="GeneID:851024"
     mRNA            complement(<762575..>764137)
                     /gene="CDC3"
                     /locus_tag="YLR314C"
                     /product="septin CDC3"
                     /transcript_id="NM_001182203.2"
                     /db_xref="GI:330443675"
                     /db_xref="GeneID:851024"
     CDS             complement(762575..764137)
                     /gene="CDC3"
                     /locus_tag="YLR314C"
                     /note="Component of the septin ring that is required for
                     cytokinesis; septins are GTP-binding proteins that
                     assemble with other septins into rod-like complexes that
                     can associate with other rods to form filament polymers;
                     septin rings at the mother-bud neck act as scaffolds for
                     recruiting factors needed for cell division and as
                     barriers to prevent diffusion of specific proteins between
                     mother and daughter cells"
                     /codon_start=1
                     /product="septin CDC3"
                     /protein_id="NP_013418.2"
                     /db_xref="GI:330443676"
                     /db_xref="SGD:S000004306"
                     /db_xref="GeneID:851024"
                     /translation="MSLKEEQVSIKQDPEQEERQHDQFNDVQIKQESQDHDGVDSQYT
                     NGTQNDDSERFEAAESDVKVEPGLGMGITSSQSEKGQVLPDQPEIKFIRRQINGYVGF
                     ANLPKQWHRRSIKNGFSFNLLCVGPDGIGKTTLMKTLFNNDDIEANLVKDYEEELAND
                     QEEEEGQGEGHENQSQEQRHKVKIKSYESVIEENGVKLNLNVIDTEGFGDFLNNDQKS
                     WDPIIKEIDSRFDQYLDAENKINRHSINDKRIHACLYFIEPTGHYLKPLDLKFMQSVY
                     EKCNLIPVIAKSDILTDEEILSFKKTIMNQLIQSNIELFKPPIYSNDDAENSHLSERL
                     FSSLPYAVIGSNDIVENYSGNQVRGRSYPWGVIEVDNDNHSDFNLLKNLLIKQFMEEL
                     KERTSKILYENYRSSKLAKLGIKQDNSVFKEFDPISKQQEEKTLHEAKLAKLEIEMKT
                     VFQQKVSEKEKKLQKSETELFARHKEMKEKLTKQLKALEDKKKQLELSINSASPNVNH
                     SPVPTKKKGFLR"
     gene            <764808..>765269
                     /gene="NKP2"
                     /locus_tag="YLR315W"
                     /db_xref="GeneID:851025"
     mRNA            <764808..>765269
                     /gene="NKP2"
                     /locus_tag="YLR315W"
                     /product="Nkp2p"
                     /transcript_id="NM_001182204.1"
                     /db_xref="GI:296146845"
                     /db_xref="GeneID:851025"
     CDS             764808..765269
                     /gene="NKP2"
                     /locus_tag="YLR315W"
                     /note="Central kinetochore protein and subunit of the
                     Ctf19 complex; mutants have elevated rates of chromosome
                     loss; orthologous to fission yeast kinetochore protein
                     cnl2"
                     /codon_start=1
                     /product="Nkp2p"
                     /protein_id="NP_013419.1"
                     /db_xref="GI:6323347"
                     /db_xref="SGD:S000004307"
                     /db_xref="GeneID:851025"
                     /translation="MNSEQLLHNYVSDSLLTTLISFQEFKQQLQSYTSDEQQLQHWYE
                     LLQARDARVTSELEARIKQFFITLRSRLLRFLESEQLSHSLSLETLIDALYKINDLLQ
                     QRLQILDDAIQEKTSELAEFENMVRSPSAGDNAIPGLLQIIQSYINLLEEN"
     gene            complement(<765266..>766358)
                     /gene="TAD3"
                     /locus_tag="YLR316C"
                     /db_xref="GeneID:851027"
     mRNA            complement(join(<765266..766073,766130..766181,
                     766250..>766358))
                     /gene="TAD3"
                     /locus_tag="YLR316C"
                     /product="Tad3p"
                     /transcript_id="NM_001182205.1"
                     /db_xref="GI:296146846"
                     /db_xref="GeneID:851027"
     CDS             complement(join(765266..766073,766130..766181,
                     766250..766358))
                     /gene="TAD3"
                     /locus_tag="YLR316C"
                     /note="Subunit of tRNA-specific adenosine-34 deaminase;
                     forms a heterodimer with Tad2p that converts adenosine to
                     inosine at the wobble position of several tRNAs"
                     /codon_start=1
                     /product="Tad3p"
                     /protein_id="NP_013420.2"
                     /db_xref="GI:9755339"
                     /db_xref="SGD:S000004308"
                     /db_xref="GeneID:851027"
                     /translation="MVKKVNNPLKIDYQNGIIENRLLQIRNFKDVNTPKLINVWSIRI
                     DPRDSKKVIELIRNDFQKNDPVSLRHLKRIRKDIETSTLEVVLCSKEYICDEGEINNK
                     LKSIWVGTKKYELSDDIEVPEFAPSTKELNNAWSVKYWPLIWNGNPNDQILNDYKIDM
                     QEVRNELSRASTLSVKMATAGKQFPMVSVFVDPSRKKDKVVAEDGRNCENSLPIDHSV
                     MVGIRAVGERLREGVDEDANSYLCLDYDVYLTHEPCSMCSMALIHSRVRRVVFLTEMQ
                     RTGSLKLTSGDGYCMNDNKQLNSTYEAFQWIGEEYPVGQVDRDVCC"
     gene            <766542..>769196
                     /gene="EST2"
                     /locus_tag="YLR318W"
                     /db_xref="GeneID:851028"
     mRNA            <766542..>769196
                     /gene="EST2"
                     /locus_tag="YLR318W"
                     /product="Est2p"
                     /transcript_id="NM_001182207.2"
                     /db_xref="GI:330443677"
                     /db_xref="GeneID:851028"
     CDS             766542..769196
                     /gene="EST2"
                     /locus_tag="YLR318W"
                     /EC_number="2.7.7.49"
                     /note="Reverse transcriptase subunit of the telomerase
                     holoenzyme; essential for telomerase core catalytic
                     activity, involved in other aspects of telomerase assembly
                     and function; mutations in human homolog are associated
                     with aplastic anemia"
                     /codon_start=1
                     /product="Est2p"
                     /protein_id="NP_013422.2"
                     /db_xref="GI:330443678"
                     /db_xref="SGD:S000004310"
                     /db_xref="GeneID:851028"
                     /translation="MKILFEFIQDKLDIDLQTNSTYKENLKCGHFNGLDEILTTCFAL
                     PNSRKIALPCLPGDLSHKAVIDHCIIYLLTGELYNNVLTFGYKIARNEDVNNSLFCHS
                     ANVNVTLLKGAAWKMFHSLVGTYAFVDLLINYTVIQFNGQFFTQIVGNRCNEPHLPPK
                     WAQRSSSSSATAAQIKQLTEPVTNKQFLHKLNINSSSFFPYSKILPSSSSIKKLTDLR
                     EAIFPTNLVKIPQRLKVRINLTLQKLLKRHKRLNYVSILNSICPPLEGTVLDLSHLSR
                     QSPKERVLKFIIVILQKLLPQEMFGSKKNKGKIIKNLNLLLSLPLNGYLPFDSLLKKL
                     RLKDFRWLFISDIWFTKHNFENLNQLAICFISWLFRQLIPKIIQTFFYCTEISSTVTI
                     VYFRHDTWNKLITPFIVEYFKTYLVENNVCRNHNSYTLSNFNHSKMRIIPKKSNNEFR
                     IIAIPCRGADEEEFTIYKENHKNAIQPTQKILEYLRNKRPTSFTKIYSPTQIADRIKE
                     FKQRLLKKFNNVLPELYFMKFDVKSCYDSIPRMECMRILKDALKNENGFFVRSQYFFN
                     TNTGVLKLFNVVNASRVPKPYELYIDNVRTVHLSNQDVINVVEMEIFKTALWVEDKCY
                     IREDGLFQGSSLSAPIVDLVYDDLLEFYSEFKASPSQDTLILKLADDFLIISTDQQQV
                     INIKKLAMGGFQKYNAKANRDKILAVSSQSDDDTVIQFCAMHIFVKELEVWKHSSTMN
                     NFHIRSKSSKGIFRSLIALFNTRISYKTIDTNLNSTNTVLMQIDHVVKNISECYKSAF
                     KDLSINVTQNMQFHSFLQRIIEMTVSGCPITKCDPLIEYEVRFTILNGFLESLSSNTS
                     KFKDNIILLRKEIQHLQAYIYIYIHIVN"
     gene            complement(<769318..>771684)
                     /gene="BUD6"
                     /locus_tag="YLR319C"
                     /gene_synonym="AIP3"
                     /db_xref="GeneID:851029"
     mRNA            complement(<769318..>771684)
                     /gene="BUD6"
                     /locus_tag="YLR319C"
                     /gene_synonym="AIP3"
                     /product="Bud6p"
                     /transcript_id="NM_001182208.1"
                     /db_xref="GI:296146848"
                     /db_xref="GeneID:851029"
     CDS             complement(769318..771684)
                     /gene="BUD6"
                     /locus_tag="YLR319C"
                     /gene_synonym="AIP3"
                     /note="Actin- and formin-interacting protein; participates
                     in actin cable assembly and organization as a
                     nucleation-promoting factor (NPF) for formins Bni1p and
                     Bnr1p; a triple helical coiled-coil domain in the
                     C-terminal region interacts with Bni1p; involved in
                     polarized cell growth; isolated as bipolar budding mutant;
                     potential Cdc28p substrate"
                     /codon_start=1
                     /product="Bud6p"
                     /protein_id="NP_013423.1"
                     /db_xref="GI:6323351"
                     /db_xref="SGD:S000004311"
                     /db_xref="GeneID:851029"
                     /translation="MKMAVDDPTYGTPKIKRTASSSSSIETTVTKLLMSTKHLLQVLT
                     QWSKGTTSGRLVSDAYVQLGNDFKVVSKFFMHAKVDMSDVGDVPMALRRVLEVTLREP
                     PSDETLNKHLPKIREIIVTLLDKLKVKQAILKNMQQEHRISVKSHHQQNPSFTSNLSL
                     GSEGTREGTPLSSRKSSIVRDQRQSDSVENSYGEKVNSTSTGTPSAQSAEATLTKPRT
                     NIKQNLKSNNAPNASDDDDALSQLKKGTNLQRRASKRYSAYHMAKLTNQSTTEAAAAA
                     GLMTTPSPSMLHLEETVRKSKLYGNNNNDDDRNINSAENKGKSIDDVSKASPLAKTPL
                     PIENVRASPRRLSSVVTTSPDKAMNGTCPVFLRIGDKTKKCHVQLPTTKNALRLLFIE
                     RFAYSPGANSFPDIYIMDPQYGVFYELEELNLLDIKEGFVIELKLEENPNNTIKEFID
                     TVKMEISNSQNDIIRHLKEMSFGSAISGKQTEVLPQPGLEANKHDLVGQNKKDDDKTI
                     KDIQYELGKIKQVHNINRSNINETIFNILRKVDNFKSLSFSAKNSSNRMYMEKSQTEL
                     GDLSDTLLSKVDDLQDVIEIMRKDVAERRSQPAKKKLETVSKDLENAQADVLKLQEFI
                     DTEKPHWKKTWEAELDKVCEEQQFLTLQEELILDLKEDLGKALETFDLIKLCCEEQEK
                     NPSRSKSNPILPIMRPGTFNQVREQVMVAVQSLNPDHDSRVEAIDKAEKMWEMERKLK
                     ASNEFDDELENFVGNSNLKKSGGFEEVERIRKQKDEANLRAYFGPGFT"
     gene            <771940..>776304
                     /gene="MMS22"
                     /locus_tag="YLR320W"
                     /gene_synonym="SLM2"
                     /db_xref="GeneID:851030"
     mRNA            <771940..>776304
                     /gene="MMS22"
                     /locus_tag="YLR320W"
                     /gene_synonym="SLM2"
                     /product="Mms22p"
                     /transcript_id="NM_001182209.1"
                     /db_xref="GI:296146849"
                     /db_xref="GeneID:851030"
     CDS             771940..776304
                     /gene="MMS22"
                     /locus_tag="YLR320W"
                     /gene_synonym="SLM2"
                     /note="Subunit of E3 ubiquitin ligase complex involved in
                     replication repair; stabilizes protein components of the
                     replication fork, such as the fork-pausing complex and
                     leading strand polymerase, preventing fork collapse and
                     promoting efficient recovery during replication stress;
                     required for accurate meiotic chromosome segregation"
                     /codon_start=1
                     /product="Mms22p"
                     /protein_id="NP_013424.1"
                     /db_xref="GI:6323352"
                     /db_xref="SGD:S000004312"
                     /db_xref="GeneID:851030"
                     /translation="MDVDEPNPIVISDSEATDEEISIIYEPEFNENYLWAEENVQEAS
                     RSQKIVTERLSLDSTAGESCTPSVVTDTQVTTGLRWSLRKRKAIQKMPYSLERIKHRQ
                     LLEGYDISSFDSISNQLTLPKNASTVIHSNDILLTKRTGKPLDEQKDVTIDSIKPENS
                     SVQSQRYDSDEEIPKKRHRTFKDLDQDIVFQSGDSTEDEQDLASTNLQNTQNDEVIFR
                     GRVLNVRTGYRGVLPRVAWEKSLQKQQSSKVTKRKTQLLNHKGVAKRKMNRSAHIEDE
                     EQNLLNDLIAPDDELDIEENAPPDIYLGNLPEDREANEKELKELQEYYESKYSEDAQS
                     AGTSGFNLNEEYRNEPVYELEYDGPGSCISHVSYKDQPIIYLNSRHSDSGFSEQYNIS
                     AEDNQSVISLDAAEEHNDGIIDKMLVKPKRIKATNDANFLNTKSKRVRRYKYKYRNSC
                     LAPSTKAIKVGKRSAHKSHLAANNPVSFVSKKNHVIDDYFFEELESQSLEQDDSSSLK
                     PQKKRRKKKAPIYSSFSADLESRRKPVFNTVVEVPTNRYAFTKPNVRNRDSINHDMEF
                     EEEDSNQELGPIMVVLDSILLKKPFEPPNFFKIQLSDKSFLLSKLNPADIATSLQKIF
                     RVIIDKGITDTELVHFNESLIAFLVHLDMPELFDLIGEFHREFRSKVNSLRKKAKPIH
                     FFQIAACQLMFLEISRYNKISAAAKFDMDVKLLDHIVSFFKLLSVCYDSVMKNPMQYL
                     YTSYYILSAVVDVIHKKEALWDLFQKHPFSPHISLLLVNIFPTKVCRWQVLRLDSEFQ
                     PLSSAFRFINYCIETCNWNVTNSLILSLDRIFKRRRFSDFEEESDLSQNNKIIYPPTN
                     QLTSRLMFNRYLHLLTLCELSSSDTQRVIPMGDISMNDSLSVLKNRLNLLIVLATRFD
                     LNLEKRFQELTRPLYSKEYLNLHTQNTVRTITTLIMQASLSFLEISRIKNHPFSGKFI
                     ASLFDKLVLQQPSISGVTENFLKEFTNLVSKMKRKSVSMLKFLYPSLVAMSQENIFES
                     SFFLLLQVYLKSLDVLGPTWVQNYLFQFIKSKAQENERWIECYCQIGKFLVDSGIFTW
                     WTFFTYNGLDAALHFQLAFHSLIIDFCDTDSFELLKKPLYSIASDLLLISKDDAFYHF
                     LSNLLKRAHIIVADLKPVSDENELLRLAYIFSKALKKNAYQDLLAVFLSLAKKHYDEG
                     DISRNFLAKYLEFLNKNCLTELRNNQLFISLRRELGISSDEDEKCAFWDSFNEAGDIL
                     SKAAFVETGIVQACCTGNEIDGYLDNLSTLFTSTMLESPFAFFSDLVIAHIFENRPFF
                     DVNIKNFLLSHFIDLFNKVLKMKFEQVSPDEFAELCKVYRALCIECATDDTFNSNSDL
                     IAAKDAFLVSVLRIADGFWEHDKLLQLRMLDSNMNIPNQIPHTTLQSSLSAIVIKIIE
                     SNIGKIEASEPFKTFKNT"
     gene            complement(<776584..>777864)
                     /gene="SFH1"
                     /locus_tag="YLR321C"
                     /db_xref="GeneID:851032"
     mRNA            complement(<776584..>777864)
                     /gene="SFH1"
                     /locus_tag="YLR321C"
                     /product="Sfh1p"
                     /transcript_id="NM_001182210.1"
                     /db_xref="GI:296146850"
                     /db_xref="GeneID:851032"
     CDS             complement(776584..777864)
                     /gene="SFH1"
                     /locus_tag="YLR321C"
                     /note="Component of the RSC chromatin remodeling complex;
                     essential gene required for cell cycle progression and
                     maintenance of proper ploidy; phosphorylated in the G1
                     phase of the cell cycle; Snf5p paralog"
                     /codon_start=1
                     /product="Sfh1p"
                     /protein_id="NP_013425.1"
                     /db_xref="GI:6323354"
                     /db_xref="SGD:S000004313"
                     /db_xref="GeneID:851032"
                     /translation="MSHQNQLIPQAYISNFHNRLTNEDDGIPIFTMAQQTRQHKRAKV
                     VNYAEYDNDLFDEFNMNGSNFNNADTHYKDNAVSHENTPALTNGVTMDGSEYNVLENM
                     NGADSIISNNKYDAGSNMVVESLSGLNSNNNASNGPSNKAQAQDIGNAVLPDLQDQHH
                     NPFNILRYPKIRDTFINGKVVSPYRLNTDQETKANANSGEAIMIPITLDIEHMGHTIK
                     DQFLWNYNDDSISPEEFASIYCKDLDMTSATLQTQIANIIKEQLKDLENIAATEIMSD
                     LHVIINLTCNLQDRFFEDNFQWNLNDKSLTPERFATSIVQDLGLTREFIPLISQSLHE
                     TILKIKKDWVDGHLIQDHVPNDAAFGYLSGIRLDIDELGSNWCPRVEILTKEEIQKRE
                     IEKERNLRRLKRETDRLSRRGRRRLDDLETTMRM"
     gene            complement(<778173..>778952)
                     /gene="CWC24"
                     /locus_tag="YLR323C"
                     /db_xref="GeneID:851033"
     mRNA            complement(<778173..>778952)
                     /gene="CWC24"
                     /locus_tag="YLR323C"
                     /product="Cwc24p"
                     /transcript_id="NM_001182212.1"
                     /db_xref="GI:296146851"
                     /db_xref="GeneID:851033"
     CDS             complement(778173..778952)
                     /gene="CWC24"
                     /locus_tag="YLR323C"
                     /note="General splicing factor; required for stable U2
                     snRNP binding to primary transcripts; essential for the
                     first step of splicing; component of the pre-catalytic
                     spliceosome complex containing Cef1p; similar to S. pombe
                     Cwf24p"
                     /codon_start=1
                     /product="Cwc24p"
                     /protein_id="NP_013427.1"
                     /db_xref="GI:6323355"
                     /db_xref="SGD:S000004315"
                     /db_xref="GeneID:851033"
                     /translation="MFRKRLVNKSSSDEKNQKKRQKINFSEEKLVASDEEKGSSDLMS
                     LAKSGNSRTLQLSHENEGKLQKKGEDLDKYTLTVNDDSTKEDLLNFERKELAEKAKKR
                     RPSDDNELVLNMSGKNKRLTKQINQPTNIRTTVLMDFQPDVCKDYKQTGYCGYGDSCK
                     FLHSRDDFKTGWKLNQEWNADKEDSKAVTLDLEKIPFKCTLCKEDYKSPVVTNCGHYF
                     CGSCFAKDMKKGTKCFICHKETHGSAKVASDLQKMLNKRKS"
     gene            <779215..>780786
                     /gene="PEX30"
                     /locus_tag="YLR324W"
                     /db_xref="GeneID:851034"
     mRNA            <779215..>780786
                     /gene="PEX30"
                     /locus_tag="YLR324W"
                     /product="Pex30p"
                     /transcript_id="NM_001182213.1"
                     /db_xref="GI:296146852"
                     /db_xref="GeneID:851034"
     CDS             779215..780786
                     /gene="PEX30"
                     /locus_tag="YLR324W"
                     /note="Peroxisomal integral membrane protein; involved in
                     negative regulation of peroxisome number; partially
                     functionally redundant with Pex31p; genetic interactions
                     suggest action at a step downstream of steps mediated by
                     Pex28p and Pex29p; PEX30 has a paralog, PEX31, that arose
                     from the whole genome duplication"
                     /codon_start=1
                     /product="Pex30p"
                     /protein_id="NP_013428.1"
                     /db_xref="GI:6323356"
                     /db_xref="SGD:S000004316"
                     /db_xref="GeneID:851034"
                     /translation="MSGNTTNVHETRAKFAETLQPRIGGNTTKVIRAALEKNEAESGV
                     SEDNDNGSLEKVNVATSPLLTSTPPTISKALVKLYPYLILIDEFLNVVTWTGKNIWSS
                     VLMLCLFITTVEYFETLVKYFGHLAIIAILWGYSLLDNYIEGTLSSSPTLEDIALLMN
                     RVSLKSDILLSPMVNLGTQDIQRLLYTTVILSPIYVMITWLLLPPRSLMLMVGMFLLT
                     YHSPWSKVARRLLWKFKIVRLLVFYVTGLDLGGINKDQGIFATVQKQVKKLASTENSN
                     GVLSDSKPIRFTYVLYENQRRWLGIGWKPSMLSYERTPWTDEFLNEAPSPENFHLPEE
                     TNTMVWRWVDKTWRLDMTNDGAIQVPNSKARTSADPSPDEGFIYYDNTWKKPSKEDSF
                     SKYTRRRRWVRTAELVKTSDFDESVINSNRNSAIEQKVEENSTNGLTAEQELGSNKQE
                     KDNAKKVGEPTTEETKEFAEASNINEGEFERISSTDEEVLKSRARDRLAKVLDDTEEK
                     EQSNPTIGRDSKKAV"
     gene            complement(<781143..>781379)
                     /gene="RPL38"
                     /locus_tag="YLR325C"
                     /db_xref="GeneID:851035"
     mRNA            complement(<781143..>781379)
                     /gene="RPL38"
                     /locus_tag="YLR325C"
                     /product="ribosomal 60S subunit protein L38"
                     /transcript_id="NM_001182214.1"
                     /db_xref="GI:296146853"
                     /db_xref="GeneID:851035"
     CDS             complement(781143..781379)
                     /gene="RPL38"
                     /locus_tag="YLR325C"
                     /note="Ribosomal 60S subunit protein L38; homologous to
                     mammalian ribosomal protein L38, no bacterial homolog"
                     /codon_start=1
                     /product="ribosomal 60S subunit protein L38"
                     /protein_id="NP_013429.1"
                     /db_xref="GI:6323357"
                     /db_xref="SGD:S000004317"
                     /db_xref="GeneID:851035"
                     /translation="MAREITDIKQFLELTRRADVKTATVKINKKLNKAGKPFRQTKFK
                     VRGSSSLYTLVINDAGKAKKLIQSLPPTLKVNRL"
     gene            <782174..>782896
                     /locus_tag="YLR326W"
                     /db_xref="GeneID:851036"
     mRNA            <782174..>782896
                     /locus_tag="YLR326W"
                     /product="hypothetical protein"
                     /transcript_id="NM_001182215.1"
                     /db_xref="GI:296146854"
                     /db_xref="GeneID:851036"
     CDS             782174..782896
                     /locus_tag="YLR326W"
                     /note="hypothetical protein; predicted to be
                     palmitoylated"
                     /codon_start=1
                     /product="hypothetical protein"
                     /protein_id="NP_013430.1"
                     /db_xref="GI:6323358"
                     /db_xref="SGD:S000004318"
                     /db_xref="GeneID:851036"
                     /translation="MSGFIKSTLLGLGQDYLEDQYQEFAEQHFQPTRDPFYETNKDGK
                     KHRRRLPYYCTKDESKAWKKVQNKAWLHDKSLCGCCCWTNTIGWAPLLALLPVIGPLL
                     MYWVHDKLIELADDRYKLPAEIKVKMHGNIVIDLLISLVPILGSVFAWLHACSTRNAA
                     IVYNFVGKRALERKQAELMHQKEENEKHSNANTAPPVVGGNKNVNGNRNNSKMYNRPP
                     VTAPPAPAYTRSTNGRPQRGYR"
     gene            complement(<783127..>783387)
                     /gene="TMA10"
                     /locus_tag="YLR327C"
                     /gene_synonym="SFL2"
                     /db_xref="GeneID:851037"
     mRNA            complement(<783127..>783387)
                     /gene="TMA10"
                     /locus_tag="YLR327C"
                     /gene_synonym="SFL2"
                     /product="Tma10p"
                     /transcript_id="NM_001182216.1"
                     /db_xref="GI:296146855"
                     /db_xref="GeneID:851037"
     CDS             complement(783127..783387)
                     /gene="TMA10"
                     /locus_tag="YLR327C"
                     /gene_synonym="SFL2"
                     /note="hypothetical protein that associates with
                     ribosomes; protein abundance increases in response to DNA
                     replication stress; TMA10 has a paralog, STF2, that arose
                     from the whole genome duplication"
                     /codon_start=1
                     /product="Tma10p"
                     /protein_id="NP_013431.1"
                     /db_xref="GI:6323359"
                     /db_xref="SGD:S000004319"
                     /db_xref="GeneID:851037"
                     /translation="MTRTSKWTVHEAKSNPKYFTHNGNFGESPNHVKRGGYGKGNWGK
                     PGDEINDLIDSGEIKTVFNKTRRGSNSQNNERRLSDLQQYHI"
     gene            784354..784453
                     /locus_tag="tX(XXX)L"
                     /db_xref="GeneID:851038"
     tRNA            join(784354..784389,784410..784453)
                     /locus_tag="tX(XXX)L"
                     /product="tRNA-Ser"
                     /note="tRNA of undetermined specificity, predicted by
                     tRNAscan-SE analysis; very similar to serine tRNAs"
                     /db_xref="SGD:S000006732"
                     /db_xref="GeneID:851038"
     gene            <784913..>786118
                     /gene="NMA1"
                     /locus_tag="YLR328W"
                     /db_xref="GeneID:851039"
     mRNA            <784913..>786118
                     /gene="NMA1"
                     /locus_tag="YLR328W"
                     /product="nicotinamide-nucleotide adenylyltransferase
                     NMA1"
                     /transcript_id="NM_001182217.1"
                     /db_xref="GI:296146856"
                     /db_xref="GeneID:851039"
     CDS             784913..786118
                     /gene="NMA1"
                     /locus_tag="YLR328W"
                     /EC_number="2.7.7.1"
                     /note="Nicotinic acid mononucleotide adenylyltransferase;
                     catalyzes the transfer of the adenylyl moiety of ATP to
                     nicotinamide mononucleotide to form NAD; involved in
                     pathways of NAD biosynthesis, including the de novo,
                     NAD(+) salvage, and nicotinamide riboside salvage
                     pathways; homolog of human NMNAT; NMA1 has a paralog,
                     NMA2, that arose from the whole genome duplication"
                     /codon_start=1
                     /product="nicotinamide-nucleotide adenylyltransferase
                     NMA1"
                     /protein_id="NP_013432.1"
                     /db_xref="GI:6323360"
                     /db_xref="SGD:S000004320"
                     /db_xref="GeneID:851039"
                     /translation="MDPTRAPDFKPPSADEELIPPPDPESKIPKSIPIIPYVLADANS
                     SIDAPFNIKRKKKHPKHHHHHHHSRKEGNDKKHQHIPLNQDDFQPLSAEVSSEDDDAD
                     FRSKERYGSDSTTESETRGVQKYQIADLEEVPHGIVRQARTLEDYEFPSHRLSKKLLD
                     PNKLPLVIVACGSFSPITYLHLRMFEMALDAISEQTRFEVIGGYYSPVSDNYQKQGLA
                     PSYHRVRMCELACERTSSWLMVDAWESLQPSYTRTAKVLDHFNHEINIKRGGVATVTG
                     EKIGVKIMLLAGGDLIESMGEPNVWADADLHHILGNYGCLIVERTGSDVRSFLLSHDI
                     MYEHRRNILIIKQLIYNDISSTKVRLFIRRAMSVQYLLPNSVIRYIQEHRLYVDQTEP
                     VKQVLGNKE"
     gene            <786442..>787333
                     /gene="REC102"
                     /locus_tag="YLR329W"
                     /db_xref="GeneID:851040"
     mRNA            join(<786442..786615,786713..>787333)
                     /gene="REC102"
                     /locus_tag="YLR329W"
                     /product="Rec102p"
                     /transcript_id="NM_001182218.1"
                     /db_xref="GI:296146857"
                     /db_xref="GeneID:851040"
     CDS             join(786442..786615,786713..787333)
                     /gene="REC102"
                     /locus_tag="YLR329W"
                     /note="Protein involved in early stages of meiotic
                     recombination; required for chromosome synapsis; forms a
                     complex with Rec104p and Spo11p necessary during the
                     initiation of recombination"
                     /codon_start=1
                     /product="Rec102p"
                     /protein_id="NP_013433.2"
                     /db_xref="GI:85666120"
                     /db_xref="SGD:S000004321"
                     /db_xref="GeneID:851040"
                     /translation="MARDITFLTVFLESCGAVNNDEAGKLLSAWTSTVRIEGPESTDS
                     NSLYIPLLPPGMLKIKLNFKMNDRLVTEEQELFTKLREIVGSSIRFWEEQLFYQVQDV
                     STIENHVILSLKCTILTDAQISTFISKPRELHTHAKGYPEIYYLSELSTTVNFFSKEG
                     NYVEISQVIPHFNEYFSSLIVSQLEFEYPMVFSMISRLRLKWQQSSLAPISYALTSNS
                     VLLPIMLNMIAQDKSSTTAYQILCRRRGPPIQNFQIFSLPAVTYNK"
     gene            <787664..>789679
                     /gene="CHS5"
                     /locus_tag="YLR330W"
                     /gene_synonym="CAL3"
                     /db_xref="GeneID:851041"
     mRNA            <787664..>789679
                     /gene="CHS5"
                     /locus_tag="YLR330W"
                     /gene_synonym="CAL3"
                     /product="Chs5p"
                     /transcript_id="NM_001182219.1"
                     /db_xref="GI:296146858"
                     /db_xref="GeneID:851041"
     CDS             787664..789679
                     /gene="CHS5"
                     /locus_tag="YLR330W"
                     /gene_synonym="CAL3"
                     /note="Component of the exomer complex; exomer also
                     contains Csh6p, Bch1p, Bch2p, and Bud7p and is involved in
                     export of selected proteins, such as chitin synthase
                     Chs3p, from the Golgi to the plasma membrane; Chs5p is the
                     only protein with a BRCT domain that is not localized to
                     the nucleus"
                     /codon_start=1
                     /product="Chs5p"
                     /protein_id="NP_013434.1"
                     /db_xref="GI:6323362"
                     /db_xref="SGD:S000004322"
                     /db_xref="GeneID:851041"
                     /translation="MSSVDVLLTVGKLDASLALLTTQDHHVIEFPTVLLPENVKAGSI
                     IKMQVSQNLEEEKKQRNHFKSIQAKILEKYGTHKPESPVLKIVNVTQTSCVLAWDPLK
                     LGSAKLKSLILYRKGIRSMVIPNPFKVTTTKISGLSVDTPYEFQLKLITTSGTLWSEK
                     VILRTHKMTDMSGITVCLGPLDPLKEISDLQISQCLSHIGARPLQRHVAIDTTHFVCN
                     DLDNEESNEELIRAKHNNIPIVRPEWVRACEVEKRIVGVRGFYLDADQSILKNYTFPP
                     VNEEELSYSKENEPVAEVADENKMPEDTTDVEQVASPNDNESNPSEAKEQGEKSGHET
                     APVSPVEDPLHASTALENETTIETVNPSVRSLKSEPVGTPNIEENKADSSAEAVVEEP
                     NEAVAESSPNEEATGQKSEDTDTHSNEQADNGFVQTEEVAENNITTESAGENNEPADD
                     AAMEFGRPEAEIETPEVNESIEDANEPAEDSNEPVEDSNKPVKDSNKPVEDSNKPVED
                     SNKPVEDSNKPVEDANEPVEDTSEPVEDAGEPVQETNEFTTDIASPRHQEEDIELEAE
                     PKDATESVAVEPSNEDVKPEEKGSEAEDDINNVSKEAASGESTTHQKTEASASLESSA
                     VTEEQETTEAEVNTDDVLSTKEAKKNTGNSNSNKKKNKKNKKKGKKK"
     gene            <790676..>791806
                     /gene="MID2"
                     /locus_tag="YLR332W"
                     /gene_synonym="KAI1"
                     /db_xref="GeneID:851042"
     mRNA            <790676..>791806
                     /gene="MID2"
                     /locus_tag="YLR332W"
                     /gene_synonym="KAI1"
                     /product="Mid2p"
                     /transcript_id="NM_001182221.1"
                     /db_xref="GI:296146859"
                     /db_xref="GeneID:851042"
     CDS             790676..791806
                     /gene="MID2"
                     /locus_tag="YLR332W"
                     /gene_synonym="KAI1"
                     /note="O-glycosylated plasma membrane protein; acts as a
                     sensor for cell wall integrity signaling and activates the
                     pathway; interacts with Rom2p, a guanine nucleotide
                     exchange factor for Rho1p, and with cell integrity pathway
                     protein Zeo1p; MID2 has a paralog, MTL1, that arose from
                     the whole genome duplication"
                     /codon_start=1
                     /product="Mid2p"
                     /protein_id="NP_013436.1"
                     /db_xref="GI:6323363"
                     /db_xref="SGD:S000004324"
                     /db_xref="GeneID:851042"
                     /translation="MLSFTTKNSFRLLLLILSCISTIRAQFFVQSSSSNSSAVSTARS
                     SVSRVSSSSSILSSSMVSSSSADSSSLTSSTSSRSLVSHTSSSTSIASISFTSFSFSS
                     DSSTSSSSSASSDSSSSSSFSISSTSATSESSTSSTQTSTSSSSSLSSTPSSSSSPST
                     ITSAPSTSSTPSTTAYNQGSTITSIINGKTILSNHYTTVTYTPSATADSSNKSKSSGL
                     SKKNRNIVIGCVVGIGVPLILVILALIYMFCIQSSRTDFIDSDGKVVTAYRANKFTKW
                     WYMLLGKKVSDEYHSDSPLGGSASSAGGLDLDEADDVMEQSSLFDVRIRDSDSVLPNA
                     NTADHNNTNSGGEPINSSVASNDIIEEKFYDEQGNELSPRNY"
     LTR             793552..793870
                     /note="Ty3 LTR"
                     /db_xref="SGD:S000007097"
     gene            793918..793989
                     /locus_tag="tD(GUC)L2"
                     /db_xref="GeneID:851044"
     tRNA            793918..793989
                     /locus_tag="tD(GUC)L2"
                     /product="tRNA-Asp"
                     /note="Aspartate tRNA (tRNA-Asp), predicted by tRNAscan-SE
                     analysis"
                     /db_xref="SGD:S000006542"
                     /db_xref="GeneID:851044"
     rep_origin      794021..794269
                     /note="ARS1226;
                     Autonomously Replicating Sequence"
                     /db_xref="SGD:S000118480"
     gene            complement(794486..794575)
                     /locus_tag="snR61"
                     /db_xref="GeneID:9164949"
     ncRNA           complement(794486..794575)
                     /locus_tag="snR61"
                     /ncRNA_class="snoRNA"
                     /product="SNR61"
                     /note="C/D box small nucleolar RNA (snoRNA); guides
                     2'-O-methylation of large subunit (LSU) rRNA at position
                     A1133"
                     /db_xref="SGD:S000006452"
                     /db_xref="GeneID:9164949"
     gene            complement(794697..794794)
                     /locus_tag="snR55"
                     /db_xref="GeneID:9164944"
     ncRNA           complement(794697..794794)
                     /locus_tag="snR55"
                     /ncRNA_class="snoRNA"
                     /product="SNR55"
                     /note="C/D box small nucleolar RNA (snoRNA); predicted to
                     guide 2'-O-methylation of small subunit (SSU) rRNA at
                     position U1269"
                     /db_xref="SGD:S000006446"
                     /db_xref="GeneID:9164944"
     gene            complement(794937..795024)
                     /locus_tag="snR57"
                     /db_xref="GeneID:9164947"
     ncRNA           complement(794937..795024)
                     /locus_tag="snR57"
                     /ncRNA_class="snoRNA"
                     /product="SNR57"
                     /note="C/D box small nucleolar RNA (snoRNA); guides
                     2'-O-methylation of small subunit (SSU) rRNA at position
                     G1572"
                     /db_xref="SGD:S000006448"
                     /db_xref="GeneID:9164947"
     gene            complement(<795573..>795899)
                     /gene="RPS25B"
                     /locus_tag="YLR333C"
                     /db_xref="GeneID:851045"
     mRNA            complement(<795573..>795899)
                     /gene="RPS25B"
                     /locus_tag="YLR333C"
                     /product="ribosomal 40S subunit protein S25B"
                     /transcript_id="NM_001182222.1"
                     /db_xref="GI:296146860"
                     /db_xref="GeneID:851045"
     CDS             complement(795573..795899)
                     /gene="RPS25B"
                     /locus_tag="YLR333C"
                     /note="Protein component of the small (40S) ribosomal
                     subunit; homologous to mammalian ribosomal protein S25, no
                     bacterial homolog; RPS25B has a paralog, RPS25A, that
                     arose from the whole genome duplication"
                     /codon_start=1
                     /product="ribosomal 40S subunit protein S25B"
                     /protein_id="NP_013437.1"
                     /db_xref="GI:6323365"
                     /db_xref="SGD:S000004325"
                     /db_xref="GeneID:851045"
                     /translation="MPPKQQLSKAAKAAAALAGGKKSKKKWSKKSMKDRAQHAVILDQ
                     EKYDRILKEVPTYRYVSVSVLVDRLKIGGSLARIALRHLEKEGIIKPISKHSKQAIYT
                     RAAASE"
     LTR             796899..797088
                     /note="Ty1 LTR"
                     /db_xref="SGD:S000007092"
     gene            797178..797249
                     /locus_tag="tE(UUC)L"
                     /db_xref="GeneID:851047"
     tRNA            797178..797249
                     /locus_tag="tE(UUC)L"
                     /product="tRNA-Glu"
                     /note="Glutamate tRNA (tRNA-Glu), predicted by tRNAscan-SE
                     analysis; thiolation of uridine at wobble position (34)
                     requires Ncs6p; target of K. lactis zymocin"
                     /db_xref="SGD:S000006559"
                     /db_xref="GeneID:851047"
     gene            <797430..>799592
                     /gene="NUP2"
                     /locus_tag="YLR335W"
                     /db_xref="GeneID:851048"
     mRNA            <797430..>799592
                     /gene="NUP2"
                     /locus_tag="YLR335W"
                     /product="Nup2p"
                     /transcript_id="NM_001182224.1"
                     /db_xref="GI:296146861"
                     /db_xref="GeneID:851048"
     CDS             797430..799592
                     /gene="NUP2"
                     /locus_tag="YLR335W"
                     /note="Nucleoporin involved in nucleocytoplasmic
                     transport; binds to either the nucleoplasmic or
                     cytoplasmic faces of the nuclear pore complex depending on
                     Ran-GTP levels; also has a role in chromatin organization"
                     /codon_start=1
                     /product="Nup2p"
                     /protein_id="NP_013439.1"
                     /db_xref="GI:6323367"
                     /db_xref="SGD:S000004327"
                     /db_xref="GeneID:851048"
                     /translation="MAKRVADAQIQRETYDSNESDDDVTPSTKVASSAVMNRRKIAMP
                     KRRMAFKPFGSAKSDETKQASSFSFLNRADGTGEAQVDNSPTTESNSRLKALNLQFKA
                     KVDDLVLGKPLADLRPLFTRYELYIKNILEAPVKSIENPTQTKGNDAKPAKVEDVQKS
                     SDSSSEDEVKVEGPKFTIDAKPPISDSVFSFGPKKENRKKDESDSENDIEIKGPEFKF
                     SGTVSSDVFKLNPSTDKNEKKTETNAKPFSFSSATSTTEQTKSKNPLSLTEATKTNVD
                     NNSKAEASFTFGTKHAADSQNNKPSFVFGQAAAKPSLEKSSFTFGSTTIEKKNDENST
                     SNSKPEKSSDSNDSNPSFSFSIPSKNTPDASKPSFSFGVPNSSKNETSKPVFSFGAAT
                     PSAKEASQEDDNNNVEKPSSKPAFNLISNAGTEKEKESKKDSKPAFSFGISNGSESKD
                     SDKPSLPSAVDGENDKKEATKPAFSFGINTNTTKTADTKAPTFTFGSSALADNKEDVK
                     KPFSFGTSQPNNTPSFSFGKTTANLPANSSTSPAPSIPSTGFKFSLPFEQKGSQTTTN
                     DSKEESTTEATGNESQDATKVDATPEESKPINLQNGEEDEVALFSQKAKLMTFNAETK
                     SYDSRGVGEMKLLKKKDDPSKVRLLCRSDGMGNVLLNATVVDSFKYEPLAPGNDNLIK
                     APTVAADGKLVTYIVKFKQKEEGRSFTKAIEDAKKEMK"
     gene            complement(<799697..>802396)
                     /gene="SGD1"
                     /locus_tag="YLR336C"
                     /db_xref="GeneID:851049"
     mRNA            complement(<799697..>802396)
                     /gene="SGD1"
                     /locus_tag="YLR336C"
                     /product="Sgd1p"
                     /transcript_id="NM_001182225.1"
                     /db_xref="GI:296146862"
                     /db_xref="GeneID:851049"
     CDS             complement(799697..802396)
                     /gene="SGD1"
                     /locus_tag="YLR336C"
                     /note="Essential nuclear protein; required for biogenesis
                     of the small ribosomal subunit; has a possible role in the
                     osmoregulatory glycerol response; putative homolog of
                     human NOM1 which is implicated in acute myeloid leukemia"
                     /codon_start=1
                     /product="Sgd1p"
                     /protein_id="NP_013440.1"
                     /db_xref="GI:6323368"
                     /db_xref="SGD:S000004328"
                     /db_xref="GeneID:851049"
                     /translation="MQKTDGIRIPGVILDELKTLDYSQDERFSISEGKKRRRGNGKHL
                     SRKEKRKMERADKKRKIISTREINSSRLKSAPTSEKRSANAGVKNVGKQANGKNPISS
                     DESESNENWDSDEVLTDEVAEESGEQAMSAEETMKKLESLKRKAKGIQGAENSGEIKG
                     NSYEKKHIRNRDTNENFVSYPLAPSDRSAFERDEMDMQYYAKKLGLKGERKAIHAKDE
                     FDAIGGLLEGLEYFENYGKSDEEYGDFATETNSMRKDDEASEKAFSSDDDLSASDFED
                     SDGLSESDNDSVADSDDNYRREKENPYVAPTQSVESYVPPSLRKKLDDSENNSTLSEI
                     SKKVNSSLNKLSDSNITIIITDLNRLYDSLPRQYVTESLTKGILNIISQNQKLLDGFI
                     MNYAALAYTLSKLRGIEVGAFFIQKTVEAFLHHYEEEMENILKDQQSKISSKICINIA
                     TLLSYCYNFGFVSCRLIYDIIRIFVADPNEFTTELLLRIISISGQLIRGDDPSALRDI
                     RSELLKNAKNLKEQSPRLRFLMDTMSDLKNNRLKPSILATDHHPLKKNLQSILNSSSS
                     WEPLQVSLEDIKNIDSKGKWWLVGASWRGNMENAFEVSINNENDASKSKKSKISIEDD
                     LLDDIPDWNIIARQQRMNTDIRRAIFISIMSAQDYLDAFSKLEKLSLKNKQVLEIPRI
                     VLHCLLADSGSNGYNHYYALVANKICERYSHLSKSFQFLFWDVIKKFEDKEFDSESDT
                     DEEDDLDDKEKLLRISNQGRFFGSLLANDILKLDVFKHVPFMGGLNTEGMLFMEILLF
                     QLFLTVAKKSEKKLKMDESGNKRIIYSDDYLRDVLTKNVKSENMLFILKGLKWFINKK
                     FRYHNFLAGKKGDKAFDRDERRLAWASKAAKSIIDKELENIDS"
     gene            complement(<802653..>805106)
                     /gene="VRP1"
                     /locus_tag="YLR337C"
                     /gene_synonym="END5; MDP2; YLR337W"
                     /db_xref="GeneID:851051"
     mRNA            complement(<802653..>805106)
                     /gene="VRP1"
                     /locus_tag="YLR337C"
                     /gene_synonym="END5; MDP2; YLR337W"
                     /product="Vrp1p"
                     /transcript_id="NM_001182226.1"
                     /db_xref="GI:296146863"
                     /db_xref="GeneID:851051"
     CDS             complement(802653..805106)
                     /gene="VRP1"
                     /locus_tag="YLR337C"
                     /gene_synonym="END5; MDP2; YLR337W"
                     /note="Proline-rich actin-associated protein; involved in
                     cytoskeletal organization and cytokinesis; promotes actin
                     nucleation and endocytosis; related to mammalian
                     Wiskott-Aldrich syndrome protein (WASP)-interacting
                     protein (WIP)"
                     /codon_start=1
                     /product="Vrp1p"
                     /protein_id="NP_013441.1"
                     /db_xref="GI:6323370"
                     /db_xref="SGD:S000004329"
                     /db_xref="GeneID:851051"
                     /translation="MAGAPAPPPPPPPPALGGSAPKPAKSVMQGRDALLGDIRKGMKL
                     KKAETNDRSAPIVGGGVVSSASGSSGTVSSKGPSMSAPPIPGMGAPQLGDILAGGIPK
                     LKHINNNASTKPSPSASAPPIPGAVPSVAAPPIPNAPLSPAPAVPSIPSSSAPPIPDI
                     PSSAAPPIPIVPSSPAPPLPLSGASAPKVPQNRPHMPSVRPAHRSHQRKSSNISLPSV
                     SAPPLPSASLPTHVSNPPQAPPPPPTPTIGLDSKNIKPTDNAVSPPSSEVPAGGLPFL
                     AEINARRSERGAVEGVSSTKIQTENHKSPSQPPLPSSAPPIPTSHAPPLPPTAPPPPS
                     LPNVTSAPKKATSAPAPPPPPLPAAMSSASTNSVKATPVPPTLAPPLPNTTSVPPNKA
                     SSMPAPPPPPPPPPGAFSTSSALSASSIPLAPLPPPPPPSVATSVPSAPPPPPTLTTN
                     KPSASSKQSKISSSSSSSAVTPGGPLPFLAEIQKKRDDRFVVGGDTGYTTQDKQEDVI
                     GSSKDDNVRPSPISPSINPPKQSSQNGMSFLDEIESKLHKQTSSNAFNAPPPHTDAMA
                     PPLPPSAPPPPITSLPTPTASGDDHTNDKSETVLGMKKAKAPALPGHVPPPPVPPVLS
                     DDSKNNVPAASLLHDVLPSSNLEKPPSPPVAAAPPLPTFSAPSLPQQSVSTSIPSPPP
                     VAPTLSVRTETESISKNPTKSPPPPPSPSTMDTGTSNSPSKNLKQRLFSTGGSTLQHK
                     HNTHTNQPDVDVGRYTIGGSNSIVGAKSGNERIVIDDSRFKWTNVSQMPKPRPFQNKT
                     KLYPSGKGSSVPLDLTLFT"
     gene            <805887..>806825
                     /gene="RPP0"
                     /locus_tag="YLR340W"
                     /gene_synonym="RPL10E"
                     /db_xref="GeneID:851052"
     mRNA            <805887..>806825
                     /gene="RPP0"
                     /locus_tag="YLR340W"
                     /gene_synonym="RPL10E"
                     /product="ribosomal protein P0"
                     /transcript_id="NM_001182229.1"
                     /db_xref="GI:296146864"
                     /db_xref="GeneID:851052"
     CDS             805887..806825
                     /gene="RPP0"
                     /locus_tag="YLR340W"
                     /gene_synonym="RPL10E"
                     /note="Conserved ribosomal protein P0 of the ribosomal
                     stalk; involved in interaction between translational
                     elongation factors and the ribosome; phosphorylated on
                     serine 302; homologous to mammalian ribosomal protein LP0
                     and bacterial L10"
                     /codon_start=1
                     /product="ribosomal protein P0"
                     /protein_id="NP_013444.1"
                     /db_xref="GI:6323371"
                     /db_xref="SGD:S000004332"
                     /db_xref="GeneID:851052"
                     /translation="MGGIREKKAEYFAKLREYLEEYKSLFVVGVDNVSSQQMHEVRKE
                     LRGRAVVLMGKNTMVRRAIRGFLSDLPDFEKLLPFVKGNVGFVFTNEPLTEIKNVIVS
                     NRVAAPARAGAVAPEDIWVRAVNTGMEPGKTSFFQALGVPTKIARGTIEIVSDVKVVD
                     AGNKVGQSEASLLNLLNISPFTFGLTVVQVYDNGQVFPSSILDITDEELVSHFVSAVS
                     TIASISLAIGYPTLPSVGHTLINNYKDLLAVAIAASYHYPEIEDLVDRIENPEKYAAA
                     APAATSAASGDAAPAEEAAAEEEEESDDDMGFGLFD"
     gene            <807385..>808818
                     /gene="SPO77"
                     /locus_tag="YLR341W"
                     /db_xref="GeneID:851054"
     mRNA            <807385..>808818
                     /gene="SPO77"
                     /locus_tag="YLR341W"
                     /product="Spo77p"
                     /transcript_id="NM_001182230.1"
                     /db_xref="GI:296146865"
                     /db_xref="GeneID:851054"
     CDS             807385..808818
                     /gene="SPO77"
                     /locus_tag="YLR341W"
                     /note="Meiosis-specific hypothetical protein; required for
                     spore wall formation during sporulation; dispensable for
                     both nuclear divisions during meiosis"
                     /codon_start=1
                     /product="Spo77p"
                     /protein_id="NP_013445.1"
                     /db_xref="GI:6323373"
                     /db_xref="SGD:S000004333"
                     /db_xref="GeneID:851054"
                     /translation="MFRRGDNSNFNVQNSFFLPLEYEYTVKDNVPSKKKSSIGFFPLD
                     DSLFTSKNNSGHHKSEQLHRGNAETIRSQFGTDAVPIRIDEKEGKWDRIQDDNSSNLN
                     YQINNSNDPASSGKYTQSIDCNHIAESKFSKKNGNIDSLRSNSATFMLNTADEDVIEF
                     SFDDNVPYAELLSGATLEKCSLTLNEINKKLFNTLYDFRVSKDNPEENLVELILPNCV
                     VLLNFFEDIELLADSSDEAFEKSTFINTIEFIVHDIWVETLIKNINLLQMFDADLKCY
                     NDKYIICKLKGQYPSTNIVDIMCRLKHFSNSILETFKFGIELKEQDQCHNRNTIINYV
                     LFSRVFSTIVLEIQKCFILIVKFMYSVNFLEKFSDEVFLSFIEILIKIVFEHQIPQLF
                     LGIDEIIQLWLKNNEGKRQQLLSAWCNGTVQDMKQSQQRESSNAESESITSSTEEDEE
                     GLQFNKWDVIEPFIDNIKALNQSKSHM"
     gene            <809997..>815627
                     /gene="FKS1"
                     /locus_tag="YLR342W"
                     /gene_synonym="CND1; CWH53; ETG1; GSC1; PBR1"
                     /db_xref="GeneID:851055"
     mRNA            <809997..>815627
                     /gene="FKS1"
                     /locus_tag="YLR342W"
                     /gene_synonym="CND1; CWH53; ETG1; GSC1; PBR1"
                     /product="1,3-beta-D-glucan synthase"
                     /transcript_id="NM_001182231.1"
                     /db_xref="GI:296146866"
                     /db_xref="GeneID:851055"
     CDS             809997..815627
                     /gene="FKS1"
                     /locus_tag="YLR342W"
                     /gene_synonym="CND1; CWH53; ETG1; GSC1; PBR1"
                     /EC_number="2.4.1.34"
                     /note="Catalytic subunit of 1,3-beta-D-glucan synthase;
                     functionally redundant with alternate catalytic subunit
                     Gsc2p; binds to regulatory subunit Rho1p; involved in cell
                     wall synthesis and maintenance; localizes to sites of cell
                     wall remodeling; FKS1 has a paralog, GSC2, that arose from
                     the whole genome duplication"
                     /codon_start=1
                     /product="1,3-beta-D-glucan synthase"
                     /protein_id="NP_013446.1"
                     /db_xref="GI:6323374"
                     /db_xref="SGD:S000004334"
                     /db_xref="GeneID:851055"
                     /translation="MNTDQQPYQGQTDYTQGPGNGQSQEQDYDQYGQPLYPSQADGYY
                     DPNVAAGTEADMYGQQPPNESYDQDYTNGEYYGQPPNMAAQDGENFSDFSSYGPPGTP
                     GYDSYGGQYTASQMSYGEPNSSGTSTPIYGNYDPNAIAMALPNEPYPAWTADSQSPVS
                     IEQIEDIFIDLTNRLGFQRDSMRNMFDHFMVLLDSRSSRMSPDQALLSLHADYIGGDT
                     ANYKKWYFAAQLDMDDEIGFRNMSLGKLSRKARKAKKKNKKAMEEANPEDTEETLNKI
                     EGDNSLEAADFRWKAKMNQLSPLERVRHIALYLLCWGEANQVRFTAECLCFIYKCALD
                     YLDSPLCQQRQEPMPEGDFLNRVITPIYHFIRNQVYEIVDGRFVKRERDHNKIVGYDD
                     LNQLFWYPEGIAKIVLEDGTKLIELPLEERYLRLGDVVWDDVFFKTYKETRTWLHLVT
                     NFNRIWVMHISIFWMYFAYNSPTFYTHNYQQLVDNQPLAAYKWASCALGGTVASLIQI
                     VATLCEWSFVPRKWAGAQHLSRRFWFLCIIFGINLGPIIFVFAYDKDTVYSTAAHVVA
                     AVMFFVAVATIIFFSIMPLGGLFTSYMKKSTRRYVASQTFTAAFAPLHGLDRWMSYLV
                     WVTVFAAKYSESYYFLVLSLRDPIRILSTTAMRCTGEYWWGAVLCKVQPKIVLGLVIA
                     TDFILFFLDTYLWYIIVNTIFSVGKSFYLGISILTPWRNIFTRLPKRIYSKILATTDM
                     EIKYKPKVLISQVWNAIIISMYREHLLAIDHVQKLLYHQVPSEIEGKRTLRAPTFFVS
                     QDDNNFETEFFPRDSEAERRISFFAQSLSTPIPEPLPVDNMPTFTVLTPHYAERILLS
                     LREIIREDDQFSRVTLLEYLKQLHPVEWECFVKDTKILAEETAAYEGNENEAEKEDAL
                     KSQIDDLPFYCIGFKSAAPEYTLRTRIWASLRSQTLYRTISGFMNYSRAIKLLYRVEN
                     PEIVQMFGGNAEGLERELEKMARRKFKFLVSMQRLAKFKPHELENAEFLLRAYPDLQI
                     AYLDEEPPLTEGEEPRIYSALIDGHCEILDNGRRRPKFRVQLSGNPILGDGKSDNQNH
                     ALIFYRGEYIQLIDANQDNYLEECLKIRSVLAEFEELNVEQVNPYAPGLRYEEQTTNH
                     PVAIVGAREYIFSENSGVLGDVAAGKEQTFGTLFARTLSQIGGKLHYGHPDFINATFM
                     TTRGGVSKAQKGLHLNEDIYAGMNAMLRGGRIKHCEYYQCGKGRDLGFGTILNFTTKI
                     GAGMGEQMLSREYYYLGTQLPVDRFLTFYYAHPGFHLNNLFIQLSLQMFMLTLVNLSS
                     LAHESIMCIYDRNKPKTDVLVPIGCYNFQPAVDWVRRYTLSIFIVFWIAFVPIVVQEL
                     IERGLWKATQRFFCHLLSLSPMFEVFAGQIYSSALLSDLAIGGARYISTGRGFATSRI
                     PFSILYSRFAGSAIYMGARSMLMLLFGTVAHWQAPLLWFWASLSSLIFAPFVFNPHQF
                     AWEDFFLDYRDYIRWLSRGNNQYHRNSWIGYVRMSRARITGFKRKLVGDESEKAAGDA
                     SRAHRTNLIMAEIIPCAIYAAGCFIAFTFINAQTGVKTTDDDRVNSVLRIIICTLAPI
                     AVNLGVLFFCMGMSCCSGPLFGMCCKKTGSVMAGIAHGVAVIVHIAFFIVMWVLESFN
                     FVRMLIGVVTCIQCQRLIFHCMTALMLTREFKNDHANTAFWTGKWYGKGMGYMAWTQP
                     SRELTAKVIELSEFAADFVLGHVILICQLPLIIIPKIDKFHSIMLFWLKPSRQIRPPI
                     YSLKQTRLRKRMVKKYCSLYFLVLAIFAGCIIGPAVASAKIHKHIGDSLDGVVHNLFQ
                     PINTTNNDTGSQMSTYQSHYYTHTPSLKTWSTIK"
     gene            <815810..>815983
                     /locus_tag="YLR342W-A"
                     /db_xref="GeneID:1466421"
     mRNA            <815810..>815983
                     /locus_tag="YLR342W-A"
                     /product="hypothetical protein"
                     /transcript_id="NM_001184569.1"
                     /db_xref="GI:296146867"
                     /db_xref="GeneID:1466421"
     CDS             815810..815983
                     /locus_tag="YLR342W-A"
                     /codon_start=1
                     /product="hypothetical protein"
                     /protein_id="NP_878133.1"
                     /db_xref="GI:33438845"
                     /db_xref="SGD:S000028571"
                     /db_xref="GeneID:1466421"
                     /translation="MNVFMPIRVFLYSYVIINSLLSSFFHQYRPLFIKNGAAFGVSNS
                     EKICVTLIVNELI"
     gene            <816094..>817761
                     /gene="GAS2"
                     /locus_tag="YLR343W"
                     /db_xref="GeneID:851056"
     mRNA            <816094..>817761
                     /gene="GAS2"
                     /locus_tag="YLR343W"
                     /product="Gas2p"
                     /transcript_id="NM_001182232.1"
                     /db_xref="GI:296146868"
                     /db_xref="GeneID:851056"
     CDS             816094..817761
                     /gene="GAS2"
                     /locus_tag="YLR343W"
                     /EC_number="2.4.1.-"
                     /note="1,3-beta-glucanosyltransferase; involved with Gas4p
                     in spore wall assembly; has similarity to Gas1p"
                     /codon_start=1
                     /product="Gas2p"
                     /protein_id="NP_013447.1"
                     /db_xref="GI:6323375"
                     /db_xref="SGD:S000004335"
                     /db_xref="GeneID:851056"
                     /translation="MNKKQNFYAAIIVAIFLCLQLSHGSSGVSFEKTPAIKIVGNKFF
                     DSESGEQFFIKGIAYQLQRSEEELSNANGAFETSYIDALADPKICLRDIPFLKMLGVN
                     TLRVYAIDPTKSHDICMEALSAEGMYVLLDLSEPDISINRENPSWDVHIFERYKSVID
                     AMSSFPNLLGYFAGNEVTNDHTNTFASPFVKAAIRDAKEYISHSNHRKIPVGYSTNDD
                     AMTRDNLARYFVCGDVKADFYGINMYEWCGYSTYGTSGYRERTKEFEGYPIPVFFSEF
                     GCNLVRPRPFTEVSALYGNKMSSVWSGGLAYMYFEEENEYGVVKINDNDGVDILPDFK
                     NLKKEFAKADPKGITEEEYLTAKEPTEVESVECPHIAVGVWEANEKLPETPDRSKCAC
                     LDEILPCEIVPFGAESGKYEEYFSYLCSKVDCSDILANGKTGEYGEFSDCSVEQKLSL
                     QLSKLYCKIGANDRHCPLNDKNVYFNLESLQPLTSESICKNVFDSIRNITYNHGDYSK
                     SNPSRSKESLNVKYPSSEERENDGTIAFKTSGFVILLISMIAAGILL"
     LTR             complement(818073..818403)
                     /note="Ty1 LTR"
                     /db_xref="SGD:S000007074"
     gene            818609..818680
                     /gene="TRR4"
                     /locus_tag="tR(CCG)L"
                     /db_xref="GeneID:851057"
     tRNA            818609..818680
                     /gene="TRR4"
                     /locus_tag="tR(CCG)L"
                     /product="tRNA-Arg"
                     /note="Arginine tRNA (tRNA-Arg), predicted by tRNAscan-SE
                     analysis; single essential nuclear tRNA gene containing
                     the tDNA-anticodon CCG (presumably CCG in the mature
                     tRNA), decodes CGG codons into arginine, one of 19 nuclear
                     tRNAs for arginine; correct folding and efficient
                     aminoacylation require Lhp1p"
                     /db_xref="SGD:S000006706"
                     /db_xref="GeneID:851057"
     gene            <819312..>820142
                     /gene="RPL26A"
                     /locus_tag="YLR344W"
                     /db_xref="GeneID:851058"
     mRNA            join(<819312..819330,819778..>820142)
                     /gene="RPL26A"
                     /locus_tag="YLR344W"
                     /product="ribosomal 60S subunit protein L26A"
                     /transcript_id="NM_001182233.1"
                     /db_xref="GI:296146869"
                     /db_xref="GeneID:851058"
     CDS             join(819312..819330,819778..820142)
                     /gene="RPL26A"
                     /locus_tag="YLR344W"
                     /note="Ribosomal 60S subunit protein L26A; binds to 5.8S
                     rRNA; non-essential even when paralog is also deleted;
                     deletion has minimal affections on ribosome biosynthesis;
                     homologous to mammalian ribosomal protein L26 and
                     bacterial L24; RPL26A has a paralog, RPL26B, that arose
                     from the whole genome duplication"
                     /codon_start=1
                     /product="ribosomal 60S subunit protein L26A"
                     /protein_id="NP_013448.1"
                     /db_xref="GI:6323376"
                     /db_xref="SGD:S000004336"
                     /db_xref="GeneID:851058"
                     /translation="MAKQSLDVSSDRRKARKAYFTAPSSQRRVLLSAPLSKELRAQYG
                     IKALPIRRDDEVLVVRGSKKGQEGKISSVYRLKFAVQVDKVTKEKVNGASVPINLHPS
                     KLVITKLHLDKDRKALIQRKGGKLE"
     gene            <820511..>822040
                     /locus_tag="YLR345W"
                     /db_xref="GeneID:851059"
     mRNA            <820511..>822040
                     /locus_tag="YLR345W"
                     /product="bifunctional fructose-2,6-bisphosphate
                     2-phosphatase/6-phosphofructo-2-kinase"
                     /transcript_id="NM_001182234.1"
                     /db_xref="GI:296146870"
                     /db_xref="GeneID:851059"
     CDS             820511..822040
                     /locus_tag="YLR345W"
                     /EC_number="3.1.3.46"
                     /EC_number="2.7.1.105"
                     /note="Similar to 6-phosphofructo-2-kinase enzymes; mRNA
                     expression is repressed by the Rfx1p-Tup1p-Ssn6p repressor
                     complex; YLR345W is not an essential gene"
                     /codon_start=1
                     /product="bifunctional fructose-2,6-bisphosphate
                     2-phosphatase/6-phosphofructo-2-kinase"
                     /protein_id="NP_013449.1"
                     /db_xref="GI:6323377"
                     /db_xref="SGD:S000004337"
                     /db_xref="GeneID:851059"
                     /translation="MPNVLSDDEELLNGLGSEIMKPSRQGNHMARTVKRWVNKERATT
                     ADLKNVNIDGVHGPVNTESYISPGQLYSTDSGNLFHAGRILVVLVGLPATSKTLLSVA
                     ITRYTRWLGVRTKSFHFSEYKESAKNIPSDYFCVVPTSKEGVAFVEKLRMQMLNDILA
                     FFNDLSGQLAIYDALNIRKIDRKNLETTFSEIGVKVLFIESIVSDQEIMNRNIALALE
                     SNDYKGLSTDEAIDEYMRRLSVNEPYYEMMTHDEELSYIKYINLGKQIIVKDNIHGYL
                     VNKIVFFLMNLRQKKGCVYFARCGTSDKDNYIHDEELNEEGIHYSQVLKDFVLQRIKQ
                     KRQAKKNSDSLVEVIDGSHDEDLKTSLIVWTGPRKRTHDTALFFSKEGIKVQQRSELR
                     QLNPGSIADLTDQQIMDKFPSEYKESLKDPYHFRFPRAESYHDLAVRMEPLLLEMEHT
                     SKDILIIAHESTLRVLYGYLMACTCVELPNLNFTRDKLVEISFSPFCNTVELLNIPLT
                     S"
     gene            complement(<822287..>822592)
                     /locus_tag="YLR346C"
                     /db_xref="GeneID:851060"
     mRNA            complement(<822287..>822592)
                     /locus_tag="YLR346C"
                     /product="hypothetical protein"
                     /transcript_id="NM_001182235.1"
                     /db_xref="GI:296146871"
                     /db_xref="GeneID:851060"
     CDS             complement(822287..822592)
                     /locus_tag="YLR346C"
                     /note="hypothetical protein found in mitochondria;
                     expression is regulated by transcription factors involved
                     in pleiotropic drug resistance, Pdr1p and Yrr1p; not an
                     essential gene; YLR346C has a paralog, YGR035C, that arose
                     from the whole genome duplication"
                     /codon_start=1
                     /product="hypothetical protein"
                     /protein_id="NP_013450.1"
                     /db_xref="GI:6323378"
                     /db_xref="SGD:S000004338"
                     /db_xref="GeneID:851060"
                     /translation="MQSISNCPIGLVSKNTINSASTIAEWVACPWKYINVVGSGRYVS
                     NKPDKITRYDLLKAAQEAEMQELLTRNDMKGRHKRNKKSKIALETIAEENSSTESLF"
     gene            complement(<823828..>826413)
                     /gene="KAP95"
                     /locus_tag="YLR347C"
                     /gene_synonym="RSL1"
                     /db_xref="GeneID:851061"
     mRNA            complement(<823828..>826413)
                     /gene="KAP95"
                     /locus_tag="YLR347C"
                     /gene_synonym="RSL1"
                     /product="Kap95p"
                     /transcript_id="NM_001182236.1"
                     /db_xref="GI:296146872"
                     /db_xref="GeneID:851061"
     CDS             complement(823828..826413)
                     /gene="KAP95"
                     /locus_tag="YLR347C"
                     /gene_synonym="RSL1"
                     /note="Karyopherin beta; forms a complex with
                     Srp1p/Kap60p; interacts with nucleoporins to mediate
                     nuclear import of NLS-containing cargo proteins via the
                     nuclear pore complex; regulates PC biosynthesis;
                     GDP-to-GTP exchange factor for Gsp1p"
                     /codon_start=1
                     /product="Kap95p"
                     /protein_id="NP_013451.1"
                     /db_xref="GI:6323379"
                     /db_xref="SGD:S000004339"
                     /db_xref="GeneID:851061"
                     /translation="MSTAEFAQLLENSILSPDQNIRLTSETQLKKLSNDNFLQFAGLS
                     SQVLIDENTKLEGRILAALTLKNELVSKDSVKTQQFAQRWITQVSPEAKNQIKTNALT
                     ALVSIEPRIANAAAQLIAAIADIELPHGAWPELMKIMVDNTGAEQPENVKRASLLALG
                     YMCESADPQSQALVSSSNNILIAIVQGAQSTETSKAVRLAALNALADSLIFIKNNMER
                     EGERNYLMQVVCEATQAEDIEVQAAAFGCLCKIMSLYYTFMKPYMEQALYALTIATMK
                     SPNDKVASMTVEFWSTICEEEIDIAYELAQFPQSPLQSYNFALSSIKDVVPNLLNLLT
                     RQNEDPEDDDWNVSMSAGACLQLFAQNCGNHILEPVLEFVEQNITADNWRNREAAVMA
                     FGSIMDGPDKVQRTYYVHQALPSILNLMNDQSLQVKETTAWCIGRIADSVAESIDPQQ
                     HLPGVVQACLIGLQDHPKVATNCSWTIINLVEQLAEATPSPIYNFYPALVDGLIGAAN
                     RIDNEFNARASAFSALTTMVEYATDTVAETSASISTFVMDKLGQTMSVDENQLTLEDA
                     QSLQELQSNILTVLAAVIRKSPSSVEPVADMLMGLFFRLLEKKDSAFIEDDVFYAISA
                     LAASLGKGFEKYLETFSPYLLKALNQVDSPVSITAVGFIADISNSLEEDFRRYSDAMM
                     NVLAQMISNPNARRELKPAVLSVFGDIASNIGADFIPYLNDIMALCVAAQNTKPENGT
                     LEALDYQIKVLEAVLDAYVGIVAGLHDKPEALFPYVGTIFQFIAQVAEDPQLYSEDAT
                     SRAAVGLIGDIAAMFPDGSIKQFYGQDWVIDYIKRTRSGQLFSQATKDTARWAREQQK
                     RQLSL"
     gene            complement(<826977..>827873)
                     /gene="DIC1"
                     /locus_tag="YLR348C"
                     /db_xref="GeneID:851063"
     mRNA            complement(<826977..>827873)
                     /gene="DIC1"
                     /locus_tag="YLR348C"
                     /product="Dic1p"
                     /transcript_id="NM_001182237.1"
                     /db_xref="GI:296146873"
                     /db_xref="GeneID:851063"
     CDS             complement(826977..827873)
                     /gene="DIC1"
                     /locus_tag="YLR348C"
                     /note="Mitochondrial dicarboxylate carrier; integral
                     membrane protein, catalyzes a dicarboxylate-phosphate
                     exchange across the inner mitochondrial membrane,
                     transports cytoplasmic dicarboxylates into the
                     mitochondrial matrix"
                     /codon_start=1
                     /product="Dic1p"
                     /protein_id="NP_013452.1"
                     /db_xref="GI:6323381"
                     /db_xref="SGD:S000004340"
                     /db_xref="GeneID:851063"
                     /translation="MSTNAKESAGKNIKYPWWYGGAAGIFATMVTHPLDLAKVRLQAA
                     PMPKPTLFRMLESILANEGVVGLYSGLSAAVLRQCTYTTVRFGAYDLLKENVIPREQL
                     TNMAYLLPCSMFSGAIGGLAGNFADVVNIRMQNDSALEAAKRRNYKNAIDGVYKIYRY
                     EGGLKTLFTGWKPNMVRGILMTASQVVTYDVFKNYLVTKLDFDASKNYTHLTASLLAG
                     LVATTVCSPADVMKTRIMNGSGDHQPALKILADAVRKEGPSFMFRGWLPSFTRLGPFT
                     MLIFFAIEQLKKHRVGMPKEDK"
     gene            <828730..>829380
                     /gene="ORM2"
                     /locus_tag="YLR350W"
                     /db_xref="GeneID:851064"
     mRNA            <828730..>829380
                     /gene="ORM2"
                     /locus_tag="YLR350W"
                     /product="Orm2p"
                     /transcript_id="NM_001182239.1"
                     /db_xref="GI:296146874"
                     /db_xref="GeneID:851064"
     CDS             828730..829380
                     /gene="ORM2"
                     /locus_tag="YLR350W"
                     /note="Protein that mediates sphingolipid homeostasis;
                     evolutionarily conserved, required for resistance to
                     agents that induce unfolded protein response; Orm1p and
                     Orm2p together control membrane biogenesis by coordinating
                     lipid homeostasis with protein quality control; protein
                     abundance increases in response to DNA replication stress;
                     ORM2 has a paralog, ORM1, that arose from the whole genome
                     duplication"
                     /codon_start=1
                     /product="Orm2p"
                     /protein_id="NP_013454.1"
                     /db_xref="GI:6323382"
                     /db_xref="SGD:S000004342"
                     /db_xref="GeneID:851064"
                     /translation="MIDRTKNESPAFEESPLTPNVSNLKPFPSQSNKISTPVTDHRRR
                     RSSSVISHVEQETFEDENDQQMLPNMNATWVDQRGAWLIHIVVIVLLRLFYSLFGSTP
                     KWTWTLTNMTYIIGFYIMFHLVKGTPFDFNGGAYDNLTMWEQINDETLYTPTRKFLLI
                     VPIVLFLISNQYYRNDMTLFLSNLAVTVLIGVVPKLGITHRLRISIPGITGRAQIS"
     gene            complement(<829489..>830364)
                     /gene="NIT3"
                     /locus_tag="YLR351C"
                     /db_xref="GeneID:851065"
     mRNA            complement(<829489..>830364)
                     /gene="NIT3"
                     /locus_tag="YLR351C"
                     /product="Nit3p"
                     /transcript_id="NM_001182240.1"
                     /db_xref="GI:296146875"
                     /db_xref="GeneID:851065"
     CDS             complement(829489..830364)
                     /gene="NIT3"
                     /locus_tag="YLR351C"
                     /EC_number="3.5.-.-"
                     /note="Nit protein; one of two proteins in S. cerevisiae
                     with similarity to the Nit domain of NitFhit from fly and
                     worm and to the mouse and human Nit protein which
                     interacts with the Fhit tumor suppressor; nitrilase
                     superfamily member"
                     /codon_start=1
                     /product="Nit3p"
                     /protein_id="NP_013455.1"
                     /db_xref="GI:6323383"
                     /db_xref="SGD:S000004343"
                     /db_xref="GeneID:851065"
                     /translation="MSASKILSQKIKVALVQLSGSSPDKMANLQRAATFIERAMKEQP
                     DTKLVVLPECFNSPYSTDQFRKYSEVINPKEPSTSVQFLSNLANKFKIILVGGTIPEL
                     DPKTDKIYNTSIIFNEDGKLIDKHRKVHLFDVDIPNGISFHESETLSPGEKSTTIDTK
                     YGKFGVGICYDMRFPELAMLSARKGAFAMIYPSAFNTVTGPLHWHLLARSRAVDNQVY
                     VMLCSPARNLQSSYHAYGHSIVVDPRGKIVAEAGEGEEIIYAELDPEVIESFRQAVPL
                     TKQRRFDVYSDVNAH"
     gene            <831116..>833539
                     /locus_tag="YLR352W"
                     /db_xref="GeneID:851066"
     mRNA            <831116..>833539
                     /locus_tag="YLR352W"
                     /product="hypothetical protein"
                     /transcript_id="NM_001182241.1"
                     /db_xref="GI:296146876"
                     /db_xref="GeneID:851066"
     CDS             831116..833539
                     /locus_tag="YLR352W"
                     /note="hypothetical protein with similarity to F-box
                     proteins; interacts with Skp1p and Cdc53p; YLR352W is not
                     an essential gene"
                     /codon_start=1
                     /product="hypothetical protein"
                     /protein_id="NP_013456.1"
                     /db_xref="GI:6323384"
                     /db_xref="SGD:S000004344"
                     /db_xref="GeneID:851066"
                     /translation="MPDLKSKTLSSQSLGAAIPPEIVYQILTYQFRDLLRNDHPGTAE
                     KFNENLTTFVKSNLTVNKTFSHICQVLIYRYCNLTTAKRFHGLLQTLKGNRCLCNKIE
                     VADFQELTSIGLGRSSEMNKMIKNLTNETLLEFLMLTKANLREFLACENIQDDLDDNI
                     IKYILSPGKVLSVVDFCGCSGTTFTESFIKALDKYYPNKSIDQYRLEPIQQNYQITCL
                     GLNDCIDLPSHVLWKILKMLPELQKLDLSHTSIDDSTLYHGIPHWKNLTHLSLATCLQ
                     VTPRAVLEFFSHHPTITDPDNTSTLEWLNVSVIAHSSSWNEVHTMFLLKKLCQHGHNK
                     TLQYLNIGGLPLHVAPSFGEDPISESTYYYQCRDSLQFIKWNFPKLKSLSIKGNSIPI
                     STLVEFLTPIDQDHPNCAQKLKFLNISGNSYVNKWTIQDSLLYTCSPSLVALEVSFDS
                     WQQIEKLNDRHEIIAYRYKNPNSVIKDISTAEQVKWKCYIDSSYGRRYWLYKTDPFLN
                     RDDLDSKSNLTRYDFEGHKIIEIINQPDFLKFAQSKIMLGCGLVPQSGIRRKLCYRDL
                     KPPVSQFLNRKGAISLGDTPLPIITPTLPRGGWRIIHNEDDNNSHVEDSQNHVNAIPR
                     RNSLLSRPTLRSNNGSSSANPFAINVSPASQIRDGLYWDRSVHDLRELSLQEQRIQEL
                     ADEQQELRTIANFEETDDEYLHDPDLQRRRSQLHLFESSRSRSGNKTRPSLTGEHSSS
                     ASFLSFSHFNHLHKRKNYYFTHPDEFVYDPKDPLTTQRYRLHFEIVNEYQVFGCIERG
                     MYRYYSLKA"
     gene            <834352..>836163
                     /gene="BUD8"
                     /locus_tag="YLR353W"
                     /db_xref="GeneID:851067"
     mRNA            <834352..>836163
                     /gene="BUD8"
                     /locus_tag="YLR353W"
                     /product="Bud8p"
                     /transcript_id="NM_001182242.1"
                     /db_xref="GI:296146877"
                     /db_xref="GeneID:851067"
     CDS             834352..836163
                     /gene="BUD8"
                     /locus_tag="YLR353W"
                     /note="Protein involved in bud-site selection; diploid
                     mutants display a unipolar budding pattern instead of the
                     wild-type bipolar pattern, and bud at the proximal pole;
                     BUD8 has a paralog, BUD9, that arose from the whole genome
                     duplication"
                     /codon_start=1
                     /product="Bud8p"
                     /protein_id="NP_013457.1"
                     /db_xref="GI:6323385"
                     /db_xref="SGD:S000004345"
                     /db_xref="GeneID:851067"
                     /translation="MIQSDEDNLDSSETTASTSYSGTSSVSSRLQLRTSLFFENLNGA
                     HGNPDAETEMATVAYETTSRGQGFAVYINNERFSQIMGASTSSSSSSNSSSITQFHDT
                     QDNNIPSNTTVRPTSLRRDNEDTVPLRNVTPSQNAAVRPERAVNSPSSQRLSCALTIS
                     TSVLMGEDVEGSPIEQEHSRVVSSLYSSLANRGNDESKNGTPPRPTSIEPNETTEHSF
                     FSYHYDDTLEPDVEEAVRLTKNKTSNVNFISSTGSKGEGETEDEVIDQYEPVNESKFI
                     PHKLKIPEKAGSIKSSTSDDSHSPGAPGTSARKIKIPQSPSLIGNILIPSHNSDSSNE
                     SSPKDHIGHNNEEKFSSKSTRKPSTSLEEEGPPIGLPSIPVLRSVSGPSKWTKTPLRL
                     ESGNSTKSDPFSRYEGHKTPSPLTKMNKKKNKTLPEHGQPLVLAPIKSQSSESDTGQN
                     SIIEKPARSIRRKQQEKTDNRKEDRHDAENIDLEARMPIQHIDTASIHSFDSGQNGFR
                     DVYSIENIIVILLCCSIVPPLFFIIGCSSRRKLVSDYRLMRLLMNKEHRAALLQGFIW
                     DVDLRWFRMFCLILGAAETVIVMAGIAIGFGVGITRE"
     gene            complement(<836350..>837357)
                     /gene="TAL1"
                     /locus_tag="YLR354C"
                     /db_xref="GeneID:851068"
     mRNA            complement(<836350..>837357)
                     /gene="TAL1"
                     /locus_tag="YLR354C"
                     /product="sedoheptulose-7-phosphate:D-glyceraldehyde-3-
                     phosphate transaldolase TAL1"
                     /transcript_id="NM_001182243.1"
                     /db_xref="GI:296146878"
                     /db_xref="GeneID:851068"
     CDS             complement(836350..837357)
                     /gene="TAL1"
                     /locus_tag="YLR354C"
                     /EC_number="2.2.1.2"
                     /note="Transaldolase, enzyme in the non-oxidative pentose
                     phosphate pathway; converts sedoheptulose 7-phosphate and
                     glyceraldehyde 3-phosphate to erythrose 4-phosphate and
                     fructose 6-phosphate; TAL1 has a paralog, NQM1, that arose
                     from the whole genome duplication"
                     /codon_start=1
                     /product="sedoheptulose-7-phosphate:D-glyceraldehyde-3-
                     phosphate transaldolase TAL1"
                     /protein_id="NP_013458.1"
                     /db_xref="GI:6323386"
                     /db_xref="SGD:S000004346"
                     /db_xref="GeneID:851068"
                     /translation="MSEPAQKKQKVANNSLEQLKASGTVVVADTGDFGSIAKFQPQDS
                     TTNPSLILAAAKQPTYAKLIDVAVEYGKKHGKTTEEQVENAVDRLLVEFGKEILKIVP
                     GRVSTEVDARLSFDTQATIEKARHIIKLFEQEGVSKERVLIKIASTWEGIQAAKELEE
                     KDGIHCNLTLLFSFVQAVACAEAQVTLISPFVGRILDWYKSSTGKDYKGEADPGVISV
                     KKIYNYYKKYGYKTIVMGASFRSTDEIKNLAGVDYLTISPALLDKLMNSTEPFPRVLD
                     PVSAKKEAGDKISYISDESKFRFDLNEDAMATEKLSEGIRKFSADIVTLFDLIEKKVT
                     A"
     gene            complement(<838066..>839253)
                     /gene="ILV5"
                     /locus_tag="YLR355C"
                     /db_xref="GeneID:851069"
     mRNA            complement(<838066..>839253)
                     /gene="ILV5"
                     /locus_tag="YLR355C"
                     /product="ketol-acid reductoisomerase"
                     /transcript_id="NM_001182244.1"
                     /db_xref="GI:296146879"
                     /db_xref="GeneID:851069"
     CDS             complement(838066..839253)
                     /gene="ILV5"
                     /locus_tag="YLR355C"
                     /EC_number="1.1.1.86"
                     /note="Acetohydroxyacid reductoisomerase and mtDNA binding
                     protein; involved in branched-chain amino acid
                     biosynthesis and maintenance of wild-type mitochondrial
                     DNA; found in mitochondrial nucleoids"
                     /codon_start=1
                     /product="ketol-acid reductoisomerase"
                     /protein_id="NP_013459.1"
                     /db_xref="GI:6323387"
                     /db_xref="SGD:S000004347"
                     /db_xref="GeneID:851069"
                     /translation="MLRTQAARLICNSRVITAKRTFALATRAAAYSRPAARFVKPMIT
                     TRGLKQINFGGTVETVYERADWPREKLLDYFKNDTFALIGYGSQGYGQGLNLRDNGLN
                     VIIGVRKDGASWKAAIEDGWVPGKNLFTVEDAIKRGSYVMNLLSDAAQSETWPAIKPL
                     LTKGKTLYFSHGFSPVFKDLTHVEPPKDLDVILVAPKGSGRTVRSLFKEGRGINSSYA
                     VWNDVTGKAHEKAQALAVAIGSGYVYQTTFEREVNSDLYGERGCLMGGIHGMFLAQYD
                     VLRENGHSPSEAFNETVEEATQSLYPLIGKYGMDYMYDACSTTARRGALDWYPIFKNA
                     LKPVFQDLYESTKNGTETKRSLEFNSQPDYREKLEKELDTIRNMEIWKVGKEVRKLRP
                     ENQ"
     gene            <840321..>840914
                     /gene="ATG33"
                     /locus_tag="YLR356W"
                     /db_xref="GeneID:851070"
     mRNA            <840321..>840914
                     /gene="ATG33"
                     /locus_tag="YLR356W"
                     /product="Atg33p"
                     /transcript_id="NM_001182245.1"
                     /db_xref="GI:296146880"
                     /db_xref="GeneID:851070"
     CDS             840321..840914
                     /gene="ATG33"
                     /locus_tag="YLR356W"
                     /note="Mitochondrial mitophagy-specific protein; required
                     primarily for mitophagy induced at post-log phase; not
                     required for other types of selective autophagy or
                     macroautophagy; conserved within fungi, but not in higher
                     eukaryotes; ATG33 has a paralog, SCM4, that arose from the
                     whole genome duplication"
                     /codon_start=1
                     /product="Atg33p"
                     /protein_id="NP_013460.1"
                     /db_xref="GI:6323388"
                     /db_xref="SGD:S000004348"
                     /db_xref="GeneID:851070"
                     /translation="MSVCLAITKGIAVSSIGLYSGLLASASLITSTTPLEVLTGSLTP
                     TLTTLKNAATALGAFASTFFCVSFFGAPPSLRHPYLLYGMLVAPLSSFVLGCASNYQS
                     RKYSKVSKESSLFPEDSKLAASELSDSIIDLGEDNHASENTPRDGKPAATTVSKPAEA
                     LHTGPPIHTKNLIAATAIAIVGFVQAVIGVYGEGQFI"
     gene            <841331..>844000
                     /gene="RSC2"
                     /locus_tag="YLR357W"
                     /db_xref="GeneID:851071"
     mRNA            <841331..>844000
                     /gene="RSC2"
                     /locus_tag="YLR357W"
                     /product="Rsc2p"
                     /transcript_id="NM_001182246.1"
                     /db_xref="GI:296146881"
                     /db_xref="GeneID:851071"
     CDS             841331..844000
                     /gene="RSC2"
                     /locus_tag="YLR357W"
                     /note="Component of the RSC chromatin remodeling complex;
                     required for expression of mid-late sporulation-specific
                     genes; involved in telomere maintenance; RSC2 has a
                     paralog, RSC1, that arose from the whole genome
                     duplication"
                     /codon_start=1
                     /product="Rsc2p"
                     /protein_id="NP_013461.1"
                     /db_xref="GI:6323389"
                     /db_xref="SGD:S000004349"
                     /db_xref="GeneID:851071"
                     /translation="MMPDDNSNSSTQNSSALYKDLRKEYESLFTLKEDSGLEISPIFN
                     VLPPKKDYPDYYAVIKNPVSFNTLKKRIPHYTDAQQFMNDVVQIPWNAKTYNTRDSGI
                     YKYALVLEKYLKDTIYPNLKEKYPQLVYPDLGPLPDEPGYEEFQQKLREKAEEVARAN
                     AARAESSSSMNSTEAARRLRKTRTSVKRESEPGTDTNNDEDYEATDMDIDNPKDADFP
                     DLIRKPLININPYTRKPLRDNRSTTPSHSGTPQPLGPRHRQVSRTQVKRGRPPIIDLP
                     YIQRMKNVMKVLKKEVLDSGIGLTDLFERLPDRHRDANYYIMIANPISLQDINKKVKT
                     RRYKTFQEFQNDFNLMLTNFRISHRGDPESIKISNILEKTFTSLARFELSKPDRSFIP
                     EGELRYPLDEVIVNNISYHVGDWALLRNQNDPQKPIVGQIFRLWKTPDGKQWLNACWY
                     YRPEQTVHRVDRLFYKNEVMKTGQYRDHLVSNLVGKCYVIHFTRYQRGNPDMKLEGPL
                     FVCEFRYNESDKIFNKIRTWKACLPEEIRDLDEATIPVNGRKFFKYPSPIRHLLPANA
                     TPHDRVPEPTMGSPDAPPLVGAVYMRPKMQRDDLGEYATSDDCPRYIIRPNDSPEEGQ
                     VDIETGTITTNTPTANALPKTGYSSSKLSSLRYNRSSMSLENQNAIGQQQIPLSRVGS
                     PGAGGPLTVQGLKQHQLQRLQQQQHQYQQQKRSQASRYNIPTIIDDLTSQASRGNLGN
                     IMIDAASSFVLPISITKNVDVLQRTDLHSQTKRSGREEMFPWKKTKGEILWFRGPSVI
                     VNERIINSGDPHLSLPLNRWFTTNKKRKLEYEEVEETMEDVTGKDKDDDGLEPDVENE
                     KESLPGPFVLGLRPSAKFTAHRLSMLRPPSSSS"
     gene            complement(<843487..>844050)
                     /locus_tag="YLR358C"
                     /db_xref="GeneID:851072"
     mRNA            complement(<843487..>844050)
                     /locus_tag="YLR358C"
                     /product="hypothetical protein"
                     /transcript_id="NM_001270756.1"
                     /db_xref="GI:398365974"
                     /db_xref="GeneID:851072"
     CDS             complement(843487..844050)
                     /locus_tag="YLR358C"
                     /note="hypothetical protein; expressed at both mRNA and
                     protein levels; partially overlaps ORF RSC2/YLR357W"
                     /codon_start=1
                     /product="hypothetical protein"
                     /protein_id="NP_001257685.1"
                     /db_xref="GI:398365975"
                     /db_xref="SGD:S000004350"
                     /db_xref="GeneID:851072"
                     /translation="MRNGKILCCHCFYNKGDHEDDEGGRSIESLCAVNLAEGLNPRTN
                     GPGKDSFSFSTSGSKPSSSLSFPVTSSMVSSTSSYSSFLFLLVVNHLFSGRLRCGSPE
                     FIIRSFTITLGPLNHNISPFVFFHGNISSLPDLLVWLCRSVRCKTSTFLVIEIGKTNE
                     EAASIIILPKLPLDACDVKSSIIVGIL"
     gene            <844282..>845730
                     /gene="ADE13"
                     /locus_tag="YLR359W"
                     /gene_synonym="BRA1; BRA8"
                     /db_xref="GeneID:851073"
     mRNA            <844282..>845730
                     /gene="ADE13"
                     /locus_tag="YLR359W"
                     /gene_synonym="BRA1; BRA8"
                     /product="adenylosuccinase ADE13"
                     /transcript_id="NM_001182248.1"
                     /db_xref="GI:296146882"
                     /db_xref="GeneID:851073"
     CDS             844282..845730
                     /gene="ADE13"
                     /locus_tag="YLR359W"
                     /gene_synonym="BRA1; BRA8"
                     /EC_number="4.3.2.2"
                     /note="Adenylosuccinate lyase; catalyzes two steps in the
                     'de novo' purine nucleotide biosynthetic pathway;
                     expression is repressed by adenine and activated by Bas1p
                     and Pho2p; mutations in human ortholog ADSL cause
                     adenylosuccinase deficiency"
                     /codon_start=1
                     /product="adenylosuccinase ADE13"
                     /protein_id="NP_013463.1"
                     /db_xref="GI:6323391"
                     /db_xref="SGD:S000004351"
                     /db_xref="GeneID:851073"
                     /translation="MPDYDNYTTPLSSRYASKEMSATFSLRNRFSTWRKLWLNLAIAE
                     KELGLTVVTDEAIEQMRKHVEITDDEIAKASAQEAIVRHDVMAHVHTFGETCPAAAGI
                     IHLGATSCFVTDNADLIFIRDAYDIIIPKLVNVINRLAKFAMEYKDLPVLGWTHFQPA
                     QLTTLGKRATLWIQELLWDLRNFERARNDIGLRGVKGTTGTQASFLALFHGNHDKVEA
                     LDERVTELLGFDKVYPVTGQTYSRKIDIDVLAPLSSFAATAHKMATDIRLLANLKEVE
                     EPFEKSQIGSSAMAYKRNPMRCERVCSLARHLGSLFSDAVQTASVQWFERTLDDSAIR
                     RISLPSAFLTADILLSTLLNISSGLVVYPKVIERRIKGELPFMATENIIMAMVEKNAS
                     RQEVHERIRVLSHQAAAVVKEEGGENDLIERVKRDEFFKPIWEELDSLLEPSTFVGRA
                     PQQVEKFVQKDVNNALQPFQKYLNDEQVKLNV"
     gene            <846103..>847422
                     /gene="VPS38"
                     /locus_tag="YLR360W"
                     /gene_synonym="VPL17"
                     /db_xref="GeneID:851074"
     mRNA            <846103..>847422
                     /gene="VPS38"
                     /locus_tag="YLR360W"
                     /gene_synonym="VPL17"
                     /product="Vps38p"
                     /transcript_id="NM_001182249.3"
                     /db_xref="GI:398365982"
                     /db_xref="GeneID:851074"
     CDS             846103..847422
                     /gene="VPS38"
                     /locus_tag="YLR360W"
                     /gene_synonym="VPL17"
                     /note="Part of a Vps34p phosphatidylinositol 3-kinase
                     complex; functions in carboxypeptidase Y (CPY) sorting;
                     binds Vps30p and Vps34p to promote production of
                     phosphatidylinositol 3-phosphate (PtdIns3P) which
                     stimulates kinase activity; required for overflow
                     degradation of misfolded proteins when ERAD is saturated"
                     /codon_start=1
                     /product="Vps38p"
                     /protein_id="NP_013464.3"
                     /db_xref="GI:398365983"
                     /db_xref="SGD:S000004352"
                     /db_xref="GeneID:851074"
                     /translation="MKRFLLSRRQRHLRMICFHNISLFRANGDSKLIKEYGDGFIPCF
                     FILESIRGELLYVSEVQSGSLRKLSFQELPKLTGASTMIVLKLVGLVPSDILCTISSD
                     KNGIIDDKWCVLCTYTIDLNKLQPINEDTVLITGTNAPVLDLIDGSYTLAAEKIKPLK
                     GLVSSHKRNISQVKIKFSLAYSSLLKLNKLLEYSSQVHEEINEISSKIEDDFLSLKNQ
                     NHWYMRTVQKSIETLEKEVLQRKKSKKNIEMAQLESNDTINHSKTELSLMSQDESIND
                     DYGSIYSRFVQIKDRLDQLRFKKLYQLIGIFHSTDLFNSDRGYIYFEKPSSVNDVINR
                     LKLKPLNIEILLRQAGESTKHREYVNSQLGYYLLFLHLTAIQIFKAPLPYRLMYYGST
                     SVIDSQYPLYFTDQMISKHQAKLIKAIHYFNADILQFKQILENYRPT"
     gene            complement(<847388..>849124)
                     /gene="DCR2"
                     /locus_tag="YLR361C"
                     /db_xref="GeneID:851075"
     mRNA            complement(<847388..>849124)
                     /gene="DCR2"
                     /locus_tag="YLR361C"
                     /product="Dcr2p"
                     /transcript_id="NM_001182250.1"
                     /db_xref="GI:296146884"
                     /db_xref="GeneID:851075"
     CDS             complement(847388..849124)
                     /gene="DCR2"
                     /locus_tag="YLR361C"
                     /EC_number="3.1.-.-"
                     /note="Phosphoesterase; involved in downregulation of the
                     unfolded protein response (UPR), at least in part via
                     dephosphorylation of Ire1p; dosage-dependent positive
                     regulator of the G1/S phase transition through control of
                     the timing of START"
                     /codon_start=1
                     /product="Dcr2p"
                     /protein_id="NP_013465.1"
                     /db_xref="GI:6323393"
                     /db_xref="SGD:S000004353"
                     /db_xref="GeneID:851075"
                     /translation="MIRLPRLYQRYLLYLVVFVVIALFYFLQAPRVEEHIGFDLALPI
                     SHVDNLWFQNKGLEGFSNDDKLVVNIGYDECFHIGRFYEGCFNRHELKSTLTDGHQYL
                     QRKRIHKDLRGSFGRRWFGKSEYLYYDVLYPALVDYFGSNLEKLNVEAVTGISKYPKD
                     KSLPFMDVSITFEPISIELLQKRSYISDINILFGVDCIQPIANWTLQKEFPLVKYRYS
                     EPAYLTYKFVGTRPVDTGAQRLQETDEGKFKIVQLADLHLGVGESECIDEYPKHEACK
                     ADPKTETFVQQVLDIEKPQLVVFTGDQIMGDRSIQDSETVLLKAVAPVIARKIPWAMV
                     WGNHDDEGSLTRWQLSEIASVLPYSLFKFSPHDTHDNTFGVGNYIYQIFSNNDTEVPV
                     GTLYFLDSHKYSTVGKIYPGYDWIKESQWKYIEDYHDVNLKFKTGLSMAFFHIPLPEY
                     LNIESKTHPGEKNPLIGMYKEGVTAPKYNSEGITTLDRLSVDVVSCGHDHCNDYCLRD
                     DSTPNKIWLCYGGGGGEGGYAGYGGTERRIRIYEINVNENNIHTWKRLNGSPKEIFDF
                     QSMLDGNSPESV"
     gene            complement(<849383..>849679)
                     /locus_tag="YLR361C-A"
                     /db_xref="GeneID:1466422"
     mRNA            complement(<849383..>849679)
                     /locus_tag="YLR361C-A"
                     /product="hypothetical protein"
                     /transcript_id="NM_001184659.3"
                     /db_xref="GI:398365988"
                     /db_xref="GeneID:1466422"
     CDS             complement(849383..849679)
                     /locus_tag="YLR361C-A"
                     /codon_start=1
                     /product="hypothetical protein"
                     /protein_id="NP_878134.3"
                     /db_xref="GI:398365989"
                     /db_xref="SGD:S000028845"
                     /db_xref="GeneID:1466422"
                     /translation="MAVSNNNNNNNSKERTQNIKEVEEKLGENPKITLKGGGKTKIMD
                     FEQLRKPHCVRPSARFPVEDTAGGLLRTGGHRPQISDEEVSKRHHEQSHGQEDH"
     gene            <849866..>852019
                     /gene="STE11"
                     /locus_tag="YLR362W"
                     /db_xref="GeneID:851076"
     mRNA            <849866..>852019
                     /gene="STE11"
                     /locus_tag="YLR362W"
                     /product="Ste11p"
                     /transcript_id="NM_001182251.1"
                     /db_xref="GI:296146886"
                     /db_xref="GeneID:851076"
     CDS             849866..852019
                     /gene="STE11"
                     /locus_tag="YLR362W"
                     /EC_number="2.7.11.25"
                     /note="Signal transducing MEK kinase; involved in
                     pheromone response and pseudohyphal/invasive growth
                     pathways where it phosphorylates Ste7p, and the high
                     osmolarity response pathway, via phosphorylation of Pbs2p;
                     regulated by Ste20p and Ste50p; protein abundance
                     increases in response to DNA replication stress"
                     /codon_start=1
                     /product="Ste11p"
                     /protein_id="NP_013466.1"
                     /db_xref="GI:6323394"
                     /db_xref="SGD:S000004354"
                     /db_xref="GeneID:851076"
                     /translation="MEQTQTAEGTDLLIGDEKTNDLPFVQLFLEEIGCTQYLDSFIQC
                     NLVTEEEIKYLDKDILIALGVNKIGDRLKILRKSKSFQRDKRIEQVNRLKNLMEKVSS
                     LSTATLSMNSELIPEKHCVIFILNDGSAKKVNVNGCFNADSIKKRLIRRLPHELLATN
                     SNGEVTKMVQDYDVFVLDYTKNVLHLLYDVELVTICHANDRVEKNRLIFVSKDQTPSD
                     KAISTSKKLYLRTLSALSQVGPSSSNLLAQNKGISHNNAEGKLRIDNTEKDRIRQIFN
                     QRPPSEFISTNLAGYFPHTDMKRLQKTMRESFRHSARLSIAQRRPLSAESNNIGDILL
                     KHSNAVDMALLQGLDQTRLSSKLDTTKIPKLAHKRPEDNDAISNQLELLSVESGEEED
                     HDFFGEDSDIVSLPTKIATPKNWLKGACIGSGSFGSVYLGMNAHTGELMAVKQVEIKN
                     NNIGVPTDNNKQANSDENNEQEEQQEKIEDVGAVSHPKTNQNIHRKMVDALQHEMNLL
                     KELHHENIVTYYGASQEGGNLNIFLEYVPGGSVSSMLNNYGPFEESLITNFTRQILIG
                     VAYLHKKNIIHRDIKGANILIDIKGCVKITDFGISKKLSPLNKKQNKRASLQGSVFWM
                     SPEVVKQTATTAKADIWSTGCVVIEMFTGKHPFPDFSQMQAIFKIGTNTTPEIPSWAT
                     SEGKNFLRKAFELDYQYRPSALELLQHPWLDAHII"
     gene            complement(<852495..>853151)
                     /gene="NMD4"
                     /locus_tag="YLR363C"
                     /db_xref="GeneID:851077"
     mRNA            complement(<852495..>853151)
                     /gene="NMD4"
                     /locus_tag="YLR363C"
                     /product="Nmd4p"
                     /transcript_id="NM_001182252.3"
                     /db_xref="GI:398365996"
                     /db_xref="GeneID:851077"
     CDS             complement(852495..853151)
                     /gene="NMD4"
                     /locus_tag="YLR363C"
                     /note="Protein that may be involved in nonsense-mediated
                     mRNA decay; interacts with Nam7p, relocalizes from nucleus
                     to cytoplasmic foci upon DNA replication stress"
                     /codon_start=1
                     /product="Nmd4p"
                     /protein_id="NP_013467.3"
                     /db_xref="GI:398365997"
                     /db_xref="SGD:S000004355"
                     /db_xref="GeneID:851077"
                     /translation="MTQYNFIIDASAFEKGLGNIKRWCSDCTEAVTLNFYIPTFTLNE
                     LDFLQQRRKSFAARESLKFIDRLDDSKFANLKVFIEFPEVLDIILWSDVMEHNDSSGK
                     INIAKLPKRLKNLLKSCIYKCYLEGNEGLHWFLISEDPQIREMAMQCNIPSCSIVDVD
                     SILSKDMNDKSFRESEKFNNMMLKNGTKEESENGREIIRTNFNKTVYASRGTGELWSP
                     "
     gene            <853461..>853718
                     /locus_tag="YLR363W-A"
                     /db_xref="GeneID:851078"
     mRNA            <853461..>853718
                     /locus_tag="YLR363W-A"
                     /product="hypothetical protein"
                     /transcript_id="NM_001184486.1"
                     /db_xref="GI:296146888"
                     /db_xref="GeneID:851078"
     CDS             853461..853718
                     /locus_tag="YLR363W-A"
                     /note="hypothetical protein; green fluorescent protein
                     (GFP)-fusion protein localizes to the nucleus; relocalizes
                     from nucleus to nucleolus upon DNA replication stress"
                     /codon_start=1
                     /product="hypothetical protein"
                     /protein_id="NP_076903.1"
                     /db_xref="GI:13129181"
                     /db_xref="SGD:S000007620"
                     /db_xref="GeneID:851078"
                     /translation="MPQKPLKVTKKAKDPRRVTKKQKNLRKAAPLQLKSKKKSLQHLK
                     KLKKSSSLTETTERLVASKVGHLELLRGTRKELEKGKKNSK"
     gene            <854062..>854391
                     /gene="GRX8"
                     /locus_tag="YLR364W"
                     /db_xref="GeneID:851079"
     mRNA            <854062..>854391
                     /gene="GRX8"
                     /locus_tag="YLR364W"
                     /product="glutathione-disulfide reductase GRX8"
                     /transcript_id="NM_001182253.3"
                     /db_xref="GI:398365998"
                     /db_xref="GeneID:851079"
     CDS             854062..854391
                     /gene="GRX8"
                     /locus_tag="YLR364W"
                     /note="Glutaredoxin that employs a dithiol mechanism of
                     catalysis; monomeric; activity is low and null mutation
                     does not affect sensitivity to oxidative stress;
                     GFP-fusion protein localizes to the cytoplasm; expression
                     strongly induced by arsenic"
                     /codon_start=1
                     /product="glutathione-disulfide reductase GRX8"
                     /protein_id="NP_013468.3"
                     /db_xref="GI:398365999"
                     /db_xref="SGD:S000004356"
                     /db_xref="GeneID:851079"
                     /translation="MSAFVTKAEEMIKSHPYFQLSASWCPDCVYANSIWNKLNVQDKV
                     FVFDIGSLPRNEQEKWRIAFQKVVGSRNLPTIVVNGKFWGTESQLHRFEAKGTLEEEL
                     TKIGLLP"
     gene            <856442..>857317
                     /gene="RPS22B"
                     /locus_tag="YLR367W"
                     /db_xref="GeneID:851082"
     mRNA            join(<856442..856574,857058..>857317)
                     /gene="RPS22B"
                     /locus_tag="YLR367W"
                     /product="ribosomal 40S subunit protein S22B"
                     /transcript_id="NM_001182256.1"
                     /db_xref="GI:296146890"
                     /db_xref="GeneID:851082"
     CDS             join(856442..856574,857058..857317)
                     /gene="RPS22B"
                     /locus_tag="YLR367W"
                     /note="Protein component of the small (40S) ribosomal
                     subunit; homologous to mammalian ribosomal protein S15A
                     and bacterial S8; RPS22B has a paralog, RPS22A, that arose
                     from the whole genome duplication"
                     /codon_start=1
                     /product="ribosomal 40S subunit protein S22B"
                     /protein_id="NP_013471.1"
                     /db_xref="GI:6323399"
                     /db_xref="SGD:S000004359"
                     /db_xref="GeneID:851082"
                     /translation="MTRSSVLADALNAINNAEKTGKRQVLLRPSSKVIIKFLQVMQKH
                     GYIGEFEYIDDHRSGKIVVQLNGRLNKCGVISPRFNVKIGDIEKWTANLLPARQFGYV
                     ILTTSAGIMDHEEARRKHVSGKILGFVY"
     gene            856710..856920
                     /locus_tag="snR44"
                     /db_xref="GeneID:9164950"
     ncRNA           856710..856920
                     /locus_tag="snR44"
                     /ncRNA_class="snoRNA"
                     /product="SNR44"
                     /note="H/ACA box small nucleolar RNA (snoRNA); guides
                     pseudouridylation of large subunit (LSU) rRNA at position
                     U1056 and small subunit (SSU) rRNA at position U106"
                     /db_xref="SGD:S000006504"
                     /db_xref="GeneID:9164950"
     gene            <857540..>859336
                     /gene="MDM30"
                     /locus_tag="YLR368W"
                     /gene_synonym="DSG1"
                     /db_xref="GeneID:851083"
     mRNA            <857540..>859336
                     /gene="MDM30"
                     /locus_tag="YLR368W"
                     /gene_synonym="DSG1"
                     /product="SCF ubiquitin ligase complex subunit MDM30"
                     /transcript_id="NM_001182257.3"
                     /db_xref="GI:398366010"
                     /db_xref="GeneID:851083"
     CDS             857540..859336
                     /gene="MDM30"
                     /locus_tag="YLR368W"
                     /gene_synonym="DSG1"
                     /note="F-box component of an SCF ubiquitin protein ligase
                     complex; associates with and is required for Fzo1p
                     ubiquitination and for mitochondria fusion; stimulates
                     nuclear export of specific mRNAs; promotes
                     ubiquitin-mediated degradation of Gal4p in some strains"
                     /codon_start=1
                     /product="SCF ubiquitin ligase complex subunit MDM30"
                     /protein_id="NP_013472.3"
                     /db_xref="GI:398366011"
                     /db_xref="SGD:S000004360"
                     /db_xref="GeneID:851083"
                     /translation="MTKRRNLFMVGSSFTIDHLPPEIWLCISKLVGTSDLHNLCLINR
                     RLYLTITSDEIWKRRCYDRWINRESLDILTGNDYDSIPVSQWYSYYLRRAKWENKIFC
                     LLWGLTEETNPQHFREKYLHILQFRHYKLATFLHRIIKQGYIPDKRPLDLITYANYLL
                     KNVRHKYVFPLFYPTNAAELKNLNNMASRDAEMIYLRLSAIDTSFDDLLDAREFILNG
                     ICSDLLQKYKKIEEFLKLRPVTRVSKLISISTDYLDCFTQPHDSVGQTNDRATGRELH
                     REDFMLLRVYSREGRGYKTIILAIIQAITKRYNVDSYLARDHLVVSEPDFPDGRAFVT
                     VNEDFQPYIFDKEDLLSVWSNNFHNAENFESTVLPALLEPISIQHLLTEFFRELLRCK
                     PRPFEGYPNRAHGLRDMFPYGKVEVPRDVTMYFAFIYDLFDGMFESGMTSLRGQMLRD
                     LLNYVNANNFGDLNIIIGQNALKEPNDCWSNKRDYVLLDDNNKIGYFYTDIETEDTLC
                     ALNQYEVDGKVFITTIDILGDIRVRLAEGLTPFQGDNDKLWESFSSVVPRTDWGLFFK
                     GYDKERRRMQLNPYIEEKLSNLANDEQPLHNL"
     gene            <859552..>861525
                     /gene="SSQ1"
                     /locus_tag="YLR369W"
                     /gene_synonym="SSC2; SSH1"
                     /db_xref="GeneID:851084"
     mRNA            <859552..>861525
                     /gene="SSQ1"
                     /locus_tag="YLR369W"
                     /gene_synonym="SSC2; SSH1"
                     /product="Hsp70 family ATPase SSQ1"
                     /transcript_id="NM_001182258.1"
                     /db_xref="GI:296146892"
                     /db_xref="GeneID:851084"
     CDS             859552..861525
                     /gene="SSQ1"
                     /locus_tag="YLR369W"
                     /gene_synonym="SSC2; SSH1"
                     /note="Mitochondrial hsp70-type molecular chaperone;
                     required for assembly of iron/sulfur clusters into
                     proteins at a step after cluster synthesis, and for
                     maturation of Yfh1p, which is a homolog of human frataxin
                     implicated in Friedreich's ataxia"
                     /codon_start=1
                     /product="Hsp70 family ATPase SSQ1"
                     /protein_id="NP_013473.1"
                     /db_xref="GI:6323401"
                     /db_xref="SGD:S000004361"
                     /db_xref="GeneID:851084"
                     /translation="MLKSGRLNFLKLNINSRLLYSTNPQLTKKVIGIDLGTTNSAVAY
                     IRDSNDKKSATIIENDEGQRTTPSIVAFDVKSSPQNKDQMKTLVGMAAKRQNAINSEN
                     TFFATKRLIGRAFNDKEVQRDMAVMPYKIVKCESNGQAYLSTSNGLIQSPSQIASILL
                     KYLKQTSEEYLGEKVNLAVITVPAYFNDSQRQATKDAGKLAGLNVLRVINEPTAAALS
                     FGIDDKRNNGLIAVYDLGGGTFDISILDIEDGVFEVRATNGDTHLGGEDFDNVIVNYI
                     IDTFIHENPEITREEITKNRETMQRLKDVSERAKIDLSHVKKTFIELPFVYKSKHLRV
                     PMTEEELDNMTLSLINRTIPPVKQALKDADIEPEDIDEVILVGGMTRMPKIRSVVKDL
                     FGKSPNSSVNPDETVALGAAIQGGILSGEIKNVLLLDVTPLTLGIETFGGAFSPLIPR
                     NTTVPVKKTEIFSTGVDGQAGVDIKVFQGERGLVRNNKLIGDLKLTGITPLPKGIPQI
                     YVTFDIDADGIINVSAAEKSSGKQQSITVIPNSGLSEEEIAKLIEEANANRAQDNLIR
                     QRLELISKADIMISDTENLFKRYEKLISSEKEYSNIVEDIKALRQAIKNFKANENDMS
                     IDVNGIKKATDALQGRALKLFQSATKNQQNQGK"
     gene            complement(<861718..>862254)
                     /gene="ARC18"
                     /locus_tag="YLR370C"
                     /db_xref="GeneID:851085"
     mRNA            complement(<861718..>862254)
                     /gene="ARC18"
                     /locus_tag="YLR370C"
                     /product="Arc18p"
                     /transcript_id="NM_001182259.3"
                     /db_xref="GI:398366016"
                     /db_xref="GeneID:851085"
     CDS             complement(861718..862254)
                     /gene="ARC18"
                     /locus_tag="YLR370C"
                     /note="Subunit of the ARP2/3 complex; ARP2/3 is required
                     for the motility and integrity of cortical actin patches"
                     /codon_start=1
                     /product="Arc18p"
                     /protein_id="NP_013474.3"
                     /db_xref="GI:398366017"
                     /db_xref="SGD:S000004362"
                     /db_xref="GeneID:851085"
                     /translation="MPAYHSTFPVDPNTDRMVGNFALLPLNTKFRGPAYPSNSDYDII
                     DECLDLFRANSFFKNFEIKSPADRVLIYGILFINDCLAHLKITTSFNEAVKVLTNVAL
                     DNFTLPGTPGFPLNNVYQVPVQDHNSMDLLKTYIQQFRQELAMRLLERVYSSTDSKEY
                     PSKFWLAFTRRRFMNKSL"
     gene            <862714..>866784
                     /gene="ROM2"
                     /locus_tag="YLR371W"
                     /db_xref="GeneID:851086"
     mRNA            <862714..>866784
                     /gene="ROM2"
                     /locus_tag="YLR371W"
                     /product="Rom2p"
                     /transcript_id="NM_001182260.1"
                     /db_xref="GI:296146894"
                     /db_xref="GeneID:851086"
     CDS             862714..866784
                     /gene="ROM2"
                     /locus_tag="YLR371W"
                     /note="GDP/GTP exchange factor (GEF) for Rho1p and Rho2p;
                     mutations are synthetically lethal with mutations in rom1,
                     which also encodes a GEF; Rom2p localization to the bud
                     surface is dependent on Ack1p; ROM2 has a paralog, ROM1,
                     that arose from the whole genome duplication"
                     /codon_start=1
                     /product="Rom2p"
                     /protein_id="NP_013475.1"
                     /db_xref="GI:6323403"
                     /db_xref="SGD:S000004363"
                     /db_xref="GeneID:851086"
                     /translation="MSETNVDSLGDRNDIYSQIFGVERRPDSFATFDSDSHGDISSQL
                     LPNRIENIQNLNVLLSEDIANDIIIAKQRRRSGVEAAIDDSDIPNNEMKGKSSNYILS
                     QQTNIKEVPDTQSLSSADNTPVSSPKKARDATSSHPIVHAKSMSHIYSTSNSASRQAK
                     HYNDHPLPPMSPRNEVYQKNKSTTAFVPKRKPSLPQLALAGLKKQSSFSTGSASTTPT
                     QARKSPLQGFGFFSRPSSKDLHEQHQHHQHIQHNNINNHNNNNTNNNGAHYQVGSSNS
                     NYPQHSHSISSRSMSLNSSTLKNIASSFQSKTSNSRKATQKYDITSNPFSDPHHHHHH
                     HHSSNSHSSLNNVHGSGNSSSVMGSSSNIGLGLKTRVSSTSLALKRYTSVSGTSLSSP
                     RRSSMTPLSASRPVMSASSKKPQVYPALLSRVATKFKSSIQLGEHKKDGLVYRDAFTG
                     QQAVDVICAIIRTSDRNLALLFGRSLDAQKLFHDVVYEHRLRDSPHEVYEFTDNSRFT
                     GTGSTNAHDPLMLLPNSSSFNSGNHSYPNSGMVPSSSTSSLNSDQATLTGSRLHMSSS
                     LSQQKNPAAIHNVNGVFTLLAECYSPTCTRDALCYSISCPRRLEQQARLNLKPNGGLK
                     RNISMALDDDDEEKPSWTSSVSKEDWENLPKKEIKRQEAIYEVYITEKNFVKSLEITR
                     DTFMKTLAETNIISADIRKNFIKHVFAHINDIYSVNRRFLKALTDRQRSSPVVRGIGD
                     IVLRFIPFFEPFVSYVASRPYAKYLIETQRSVNPYFARFDDDMMSSSLRHGIDSFLSQ
                     GVSRPGRYMLLVKEIMKSTDPEKDKSDYEDLSKAMDALRDFMKRIDQASGAAQDRHDV
                     KLLKQKILFKNEYVNLGLNDERRKIKHEGILSRKELSKSDGTVVGDIQFYLLDNMLLF
                     LKAKAVNKWHQHKVFQRPIPLPLLFACPGEDMPALRKYIGDHPDCSGTVIQPEYNTSN
                     PKNAITFLYYGAKQRYQVTLYAAQYAGLQTLLEKIKQGQAAIISKTEMFNVTKMSDRF
                     FDYTNKINSVTSCDGGRKLLIATNSGLYMSNIKRQQNKDHRHKSSAFFSTPIQLVQRN
                     NITQIAVLEEFKSIILLIDKKLYSCPLSLIEAEGNGTSFFKKHHKELINHVSFFAEGD
                     CNGKRLIVTAHSSSHSIKYFEHEHPLLAEKNGSGSGNKKSLKKKITEVIFDSEPVSIS
                     FLKANLCIGCKKGFQIVSISQNAHESLLDPADTSLEFALRDTLKPMAIYRVGNMFLLC
                     YTEFAFFVNNQGWRKKESHIIHWEGEPQKFAIWYPYILAFDSNFIEIRKIETGELIRC
                     VLADKIRLLQTSTQEILYCYEDYRGYDT