LOCUS NC_001145 924431 bp DNA linear PLN 25-FEB-2013
DEFINITION Saccharomyces cerevisiae S288c chromosome XIII, complete sequence.
ACCESSION NC_001145
VERSION NC_001145.3 GI:330443688
DBLINK Project: 128
KEYWORDS TPA:inferential.
SOURCE Saccharomyces cerevisiae S288c
ORGANISM Saccharomyces cerevisiae S288c
Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina;
Saccharomycetes; Saccharomycetales; Saccharomycetaceae;
Saccharomyces.
REFERENCE 1 (bases 1 to 924431)
AUTHORS Bowman,S., Churcher,C., Badcock,K., Brown,D., Chillingworth,T.,
Connor,R., Dedman,K., Devlin,K., Gentles,S., Hamlin,N., Hunt,S.,
Jagels,K., Lye,G., Moule,S., Odell,C., Pearson,D., Rajandream,M.,
Rice,P., Skelton,J., Walsh,S., Whitehead,S. and Barrell,B.
TITLE The nucleotide sequence of Saccharomyces cerevisiae chromosome XIII
JOURNAL Nature 387 (6632 SUPPL), 90-93 (1997)
PUBMED 9169872
REFERENCE 2 (bases 1 to 924431)
AUTHORS Goffeau,A., Barrell,B.G., Bussey,H., Davis,R.W., Dujon,B.,
Feldmann,H., Galibert,F., Hoheisel,J.D., Jacq,C., Johnston,M.,
Louis,E.J., Mewes,H.W., Murakami,Y., Philippsen,P., Tettelin,H. and
Oliver,S.G.
TITLE Life with 6000 genes
JOURNAL Science 274 (5287), 546 (1996)
PUBMED 8849441
REFERENCE 3 (bases 1 to 924431)
CONSRTM NCBI Genome Project
TITLE Direct Submission
JOURNAL Submitted (14-FEB-2013) National Center for Biotechnology
Information, NIH, Bethesda, MD 20894, USA
REFERENCE 4 (bases 1 to 924431)
CONSRTM Saccharomyces Genome Database
TITLE Direct Submission
JOURNAL Submitted (04-MAY-2012) Department of Genetics, Stanford
University, Stanford, CA 94305-5120, USA
REMARK Protein update by submitter
REFERENCE 5 (bases 1 to 924431)
CONSRTM Saccharomyces Genome Database
TITLE Direct Submission
JOURNAL Submitted (31-MAR-2011) Department of Genetics, Stanford
University, Stanford, CA 94305-5120, USA
REMARK Sequence update by submitter
REFERENCE 6 (bases 1 to 924431)
CONSRTM Saccharomyces Genome Database
TITLE Direct Submission
JOURNAL Submitted (14-DEC-2009) Department of Genetics, Stanford
University, Stanford, CA 94305-5120, USA
COMMENT PROVISIONAL REFSEQ: This record has not yet been subject to final
NCBI review. The reference sequence is identical to BK006946.
On Apr 26, 2011 this sequence version replaced gi:44829554.
Sequence assembly version R64-1-1.
PRIMARY REFSEQ_SPAN PRIMARY_IDENTIFIER PRIMARY_SPAN COMP
1-21329 Z50178.1 1-21330
20363-32824 Z49218.1 1-12461
32749-60307 Z49210.1 1-27559
60294-74134 X80835.1 1-13841
74094-106241 Z46660.1 1-32148
106179-131313 Z46373.1 1-25135
131233-151207 Z38114.1 1-19975
151026-171976 Z46729.1 1-20951
171943-192610 Z47816.1 1-20668
192489-201909 Z48430.1 1-9421
201896-236401 Z46659.1 1-34506
235939-265304 Z49810.1 1-29366
265287-297768 Z48613.1 1-32481
297715-327725 Z49211.1 1-30011
327595-342855 Z49213.1 1-15261
342823-366927 Z48502.1 1-24105
366920-396340 Z49703.1 1-29421
395925-418055 Z48952.1 1-22131
417982-456642 Z49259.1 1-38661
456149-470348 Z49807.1 1-14200
470317-470847 Z50179.1 1-531
470816-506626 Z49702.1 1-35811
506364-519337 Z49273.1 1-12974
518882-535160 Z48622.1 1-16279
535053-564044 Z47071.1 1-28992
563680-604879 Z49705.1 1-41200
604798-637458 Z49808.1 1-32661
637434-664899 Z47815.1 1-27466
664865-681131 Z48755.1 1-16267
681065-709265 Z49809.1 1-28201
708954-749350 Z49939.1 1-40397
749346-765193 Z48756.1 1-15848
765170-788667 Z48639.1 1-23498
788528-818513 Z49260.1 1-29987
818375-849245 Z49704.1 1-30871
849195-864775 X80836.1 1-15581
864433-893718 Z49212.1 1-29286
893619-924431 Z54141.1 1-30812
FEATURES Location/Qualifiers
source 1..924431
/organism="Saccharomyces cerevisiae S288c"
/mol_type="genomic DNA"
/strain="S288c"
/db_xref="taxon:559292"
/chromosome="XIII"
telomere complement(1..6344)
/note="TEL13L; Telomeric region on the left arm of
Chromosome XIII, composed of an X element core sequence, X
element combinatorial repeats, a short region of telomeric
repeats, a short Y' element, and a short terminal region
of telomeric repeats"
/db_xref="SGD:S000028918"
repeat_region complement(1..51)
/note="TEL13L-TR1; Terminal stretch of telomeric repeats
on the left arm of Chromosome XIII"
/rpt_family="Telomeric Repeat"
/db_xref="SGD:S000028919"
repeat_region complement(52..5537)
/note="TEL13L-YP; Telomeric short Y' element on the left
arm of Chromosome XIII; contains an ARS consensus
sequence, a region of 36-bp repeats, and three ORFs
(YML133C, YML133W-A, YML133W-B)"
/rpt_family="Y' element"
/db_xref="SGD:S000028923"
gene complement(461..4684)
/locus_tag="YML133C"
/db_xref="GeneID:854906"
mRNA complement(join(461..3791,3891..4684))
/locus_tag="YML133C"
/product="Y' element ATP-dependent helicase"
/transcript_id="NM_001182496.1"
/db_xref="GI:296146986"
/db_xref="GeneID:854906"
CDS complement(join(461..3791,3891..4684))
/locus_tag="YML133C"
/EC_number="3.6.1.-"
/note="Putative Y' element ATP-dependent helicase; the
authentic, non-tagged protein is detected in highly
purified mitochondria in high-throughput studies; YML133C
contains an intron"
/codon_start=1
/product="Y' element ATP-dependent helicase"
/protein_id="NP_013573.1"
/db_xref="GI:6323502"
/db_xref="SGD:S000004602"
/db_xref="GeneID:854906"
/translation="MKVSDRRKFEKANFDEFESALNNKNDLVHCPSITLFESIPTEVR
SFYEDEKSGLIKVVKFRTGAMDRKRSFEKIVVSVMVGKNVQKFLTFVEDEPDFQGGPI
PSKYLIPKKINLMVYTLFQVHTLKFNRKDYDTLSLFYLNRGYYNELSFRVLERCHEIA
SARPNDSSTMRTFTDFVSGAPIVRSLQKSTIRRYGYNLAPHMFLLLHVDELSIFSAYQ
ASLPGEKKVDTERLKRDLCPRKPIEIKYFSQICNDMMNKKDRLGDVLATAQRIRRRYN
KNSSSEPRLKTLDGLTSERWIQWLGLESDYHCSFSSTRNAEDVVAGEAASSDHHQKIS
RVTRKRPREPKSTNDILVAGQKLFGSSFEFRDLHQLRLCHEIYMADTPSVAVQAPPGY
GKTELFHLPLIALASKGDVKYVSFLFVPYTVLLANCMIRLSRCGCLNVAPVRNFIEEG
CDGVTDLYVGIYDDLASTNFTDRIAAWENIVECTFRTNNVKLGYLIVDEFHNFETEVY
RQSQFGGITNLDFDAFEKAIFLSGTAPEAVADAALQRIGLTGLAKKSMDINELKRSED
LSRGLSSYPTRMFNLIKEKSEVPLGHVHKIWKKVESQPEEALKLLLALFEIEPESKAI
VVASTTNEVEELACSWRKYFRVVWIHGKLGAAEKVSRTKEFVTDGSMRVLIGTKLVTE
GIDIKQLMMVIMLDNRLNIIELIQGVGRLRDGGLCYLLSRKNSWAARNRKGELPPIKE
GCITEQVREFYGLESKKGKKGQHVGCCGSRTDLSADTVELIERMDRLAEKQATASMSI
VALPSSFQESNSSDRCRKYCSSDEDSDTCIHGSANASTNATTNSSTNATTTASTNVRT
SATTTASINVRTSATTTESTNSSTNATTTASTNVRTSATTTASINVRTSATTTESTNS
NTSATTTESTDSNTSATTTESTDSNTSATTTASTNSSTNATTTASTNSSTNATTTEST
NASAKEDANKDGNAEDNRFHPVTDINKESYKRKGSQMVLLERKKLKAQFPNTSENMNV
LQFLGFRSDEIKHLFLYGIDIYFCPEGVFTQYGLCKGCQKMFELCVCWAGQKVSYRRM
AWEALAVERMLRNDEEYKEYLEDIEPYHGDPVGYLKFFSVKRGEIYSQIQRNYAWYLA
ITRRRETISVLDSTRGKQGSQVFRMSGRQIKELYYKVWSNLRESKTEVLQYFLNWDEK
KCREEWEAKDDTVFVEALEKVGVFQRLRSMTSAGLQGPQYVKLQFSRHHRQLRSRYEL
SLGMHLRDQLALGVTPSKVPHWTAFLSMLIGLFYNKTFRQKLEYLLEQISEVWLLPHW
VDLANVEVLAADNTRVPLYMLMVAVHKELDSDDVPDGRFDIILLCRDSSREVGE"
repeat_region complement(5538..5585)
/note="TEL13L-TR2; Internal stretch of telomeric repeats
on the left arm of Chromosome XIII"
/rpt_family="Telomeric Repeat"
/db_xref="SGD:S000028920"
repeat_region complement(5586..5874)
/note="TEL13L-XR; Telomeric X element combinatorial Repeat
region on the left arm of Chromosome XIII; contains
repeats of the D, C, B and A types, as well as Tbf1p
binding sites; formerly called SubTelomeric Repeats"
/rpt_family="X element Combinatorial Repeats"
/db_xref="SGD:S000028922"
repeat_region complement(5875..6344)
/note="TEL13L-XC; Telomeric X element Core sequence on the
left arm of Chromosome XIII, contains an ARS consensus
sequence and an Abf1p binding site consensus sequence"
/rpt_family="X element Core sequence"
/db_xref="SGD:S000028921"
gene 7244..8383
/gene="COS3"
/locus_tag="YML132W"
/db_xref="GeneID:854907"
mRNA 7244..8383
/gene="COS3"
/locus_tag="YML132W"
/product="Cos3p"
/transcript_id="NM_001182495.1"
/db_xref="GI:296146987"
/db_xref="GeneID:854907"
CDS 7244..8383
/gene="COS3"
/locus_tag="YML132W"
/note="Protein involved in salt resistance; interacts with
sodium:hydrogen antiporter Nha1p; member of the DUP380
subfamily of conserved, often subtelomerically-encoded
proteins"
/codon_start=1
/product="Cos3p"
/protein_id="NP_013574.1"
/db_xref="GI:6323503"
/db_xref="SGD:S000004601"
/db_xref="GeneID:854907"
/translation="MKENELKNEKSVDVLSFKQLESQKIVLPQDLFRSSFTWFCYEIY
KSLAFRIWMLLWLPLSVWWKLSNNCIYPLIVSLLVLFLGPIFVLVICGLSRKRSLSKQ
LIQFCKEITENTPSSDPHDWEVVAANLNSYLYENNVWNTKYFFFNAMVCQEAFRTTLL
EPFSLKKDKAAKVKSFKDSVPYIEEALGVYFTEVEKQWKLFNTEKSWSPVGLEDAKLP
KEAYRFKLTWFLKRISNIFMLIPFLNFLCCIYVSRGMCLLLRTLYLGWILFMLVQGFQ
NIRVLIMSMEHKMQFLSTIINEQESGANGWDEIARKMNRYLFEKKAWKNEEFFFDGID
CEWFFNHFFYRVLSAKKSMWPLPLNVELWPYIKEAQLSRSEVLLV"
gene 10198..11295
/locus_tag="YML131W"
/db_xref="GeneID:854908"
mRNA 10198..11295
/locus_tag="YML131W"
/product="hypothetical protein"
/transcript_id="NM_001182494.1"
/db_xref="GI:296146988"
/db_xref="GeneID:854908"
CDS 10198..11295
/locus_tag="YML131W"
/note="hypothetical protein; similar to medium chain
dehydrogenase/reductases; expression induced by stresses
including osmotic shock, DNA damaging agents, and other
chemicals; GFP-fusion protein localizes to the cytoplasm;
protein abundance increases in response to DNA replication
stress"
/codon_start=1
/product="hypothetical protein"
/protein_id="NP_013575.1"
/db_xref="GI:6323504"
/db_xref="SGD:S000004600"
/db_xref="GeneID:854908"
/translation="MVLAKQWVLKNLPTPGEPFNFHFHDPACTFELIEKELSSEQLKD
GELLLETTYLSNDPAQKFWISSMDKNYAKGVQPGEIIPARGIGKVLASRNKAFSPGDY
VSAVTGWTTHAIISQENVQGLRKLDKNKVGKLWWYLSVLGGTSLTAYFIFFTYAQLQE
REEDYGKVYLISGAAGAVGTVCIQLALNVFKASKVIAIAGGPEKVAFVESFGDNVVGV
DYKDPSFKQKLIEAAGGENTVDYFIDNVGSNVLEAGVLLLKQRAMLIACGAISAYNDP
SKFVFKGYSFILTKRLVVKGVLVTDNIDDFPKALDKLGSLVKHGKIDLLKSATLEDGT
GDKFKNVPLIWKGLFSGVNKGKLITKVNNEE"
gene complement(11483..13174)
/gene="ERO1"
/locus_tag="YML130C"
/db_xref="GeneID:854909"
mRNA complement(11483..13174)
/gene="ERO1"
/locus_tag="YML130C"
/product="Ero1p"
/transcript_id="NM_001182493.1"
/db_xref="GI:296146989"
/db_xref="GeneID:854909"
CDS complement(11483..13174)
/gene="ERO1"
/locus_tag="YML130C"
/EC_number="1.8.4.-"
/note="Thiol oxidase required for oxidative protein
folding in the ER; essential for maintaining proper redox
balance in ER; feedback regulation of Ero1p occurs via
reduction and oxidation of Ero1p regulatory bonds; reduced
Pdi1p activates Ero1p by direct reduction of Ero1p
regulatory bonds; depletion of thiol substrates and
accumulation of oxidized Pdi1p results in inactivation of
Ero1p by both Pdi1p-mediated oxidation and autonomous
oxidation of Ero1p regulatory bonds"
/codon_start=1
/product="Ero1p"
/protein_id="NP_013576.1"
/db_xref="GI:6323505"
/db_xref="SGD:S000004599"
/db_xref="GeneID:854909"
/translation="MRLRTAIATLCLTAFTSATSNNSYIATDQTQNAFNDTHFCKVDR
NDHVSPSCNVTFNELNAINENIRDDLSALLKSDFFKYFRLDLYKQCSFWDANDGLCLN
RACSVDVVEDWDTLPEYWQPEILGSFNNDTMKEADDSDDECKFLDQLCQTSKKPVDIE
DTINYCDVNDFNGKNAVLIDLTANPERFTGYGGKQAGQIWSTIYQDNCFTIGETGESL
AKDAFYRLVSGFHASIGTHLSKEYLNTKTGKWEPNLDLFMARIGNFPDRVTNMYFNYA
VVAKALWKIQPYLPEFSFCDLVNKEIKNKMDNVISQLDTKIFNEDLVFANDLSLTLKD
EFRSRFKNVTKIMDCVQCDRCRLWGKIQTTGYATALKILFEINDADEFTKQHIVGKLT
KYELIALLQTFGRLSESIESVNMFEKMYGKRLNGSENRLSSFFQNNFFNILKEAGKSI
RYTIENINSTKEGKKKTNNSQSHVFDDLKMPKAEIVPRPSNGTVNKWKKAWNTEVNNV
LEAFRFIYRSYLDLPRNIWELSLMKVYKFWNKFIGVADYVSEETREPISYKLDIQ"
gene complement(14541..14753)
/gene="COX14"
/locus_tag="YML129C"
/db_xref="GeneID:854910"
mRNA complement(14541..14753)
/gene="COX14"
/locus_tag="YML129C"
/product="Cox14p"
/transcript_id="NM_001182492.1"
/db_xref="GI:296146990"
/db_xref="GeneID:854910"
CDS complement(14541..14753)
/gene="COX14"
/locus_tag="YML129C"
/note="Mitochondrial membrane protein, involved in
translational regulation of Cox1p and assembly of
cytochrome c oxidase (complex IV); associates with complex
IV assembly intermediates and complex III/complex IV
supercomplexes"
/codon_start=1
/product="Cox14p"
/protein_id="NP_013577.1"
/db_xref="GI:6323506"
/db_xref="SGD:S000004598"
/db_xref="GeneID:854910"
/translation="MSKYAWYTRVTDTLHRLTVLTLVGGTLYMSGGLAYTLYMNGKKY
EQQVTQQKALEEDNQQLQSPTAPPTE"
gene complement(15135..16676)
/gene="MSC1"
/locus_tag="YML128C"
/db_xref="GeneID:854911"
mRNA complement(15135..16676)
/gene="MSC1"
/locus_tag="YML128C"
/product="Msc1p"
/transcript_id="NM_001182491.1"
/db_xref="GI:296146991"
/db_xref="GeneID:854911"
CDS complement(15135..16676)
/gene="MSC1"
/locus_tag="YML128C"
/note="hypothetical protein; mutant is defective in
directing meiotic recombination events to homologous
chromatids; the authentic, non-tagged protein is detected
in highly purified mitochondria and is phosphorylated"
/codon_start=1
/product="Msc1p"
/protein_id="NP_013578.1"
/db_xref="GI:6323507"
/db_xref="SGD:S000004597"
/db_xref="GeneID:854911"
/translation="MKQFKLVNAVSASFVLIGLVLANSDSVFDKWTQEDLADYLRDNK
KSLEKYATDSIEDLKTEASQVWDKHAQPKPWWQVWSSDSSSVSNSNPGWFGYTGSSDH
PVSDWLFDTWSTDSLRNFLKKNGVDVDDAKASKDSLVKTAKENFNKISKSLKSSGYYP
SSSYFDSWSTKDLQNWLNDNGIDYDKAVQSKDELVQKVKENIYRTSEKAEQQRLGLLE
SLDLAHQQILDTSGQIKDTVFDKWSSDQLTNWLESHKVNIDKNMAKKHDYLVRMAKEN
SANLKDDIYWYLDYMKRESSPFLTKTPEYVGSVWDSSKNFLTNLYSKFRGKTDNVIND
TFLVGLDSWPKDKLKMFLDARGIKYSMLSTEHQLRELVKKSRNEKLKILPKDYQKYFD
NSNWSLDDIKGWFADKKDDFQDSQTYSTIMQDFDKVSKNTNDAKDQIAKTWSNTFQSW
SQEDLLQYLKSFGVPVKQTSTKDDLINLAKQNTQWLFGTVKEPAYKRYLHNVKNWSKS
ILGFN"
gene 17064..18809
/gene="RSC9"
/locus_tag="YML127W"
/db_xref="GeneID:854912"
mRNA 17064..18809
/gene="RSC9"
/locus_tag="YML127W"
/product="Rsc9p"
/transcript_id="NM_001182490.1"
/db_xref="GI:296146992"
/db_xref="GeneID:854912"
CDS 17064..18809
/gene="RSC9"
/locus_tag="YML127W"
/note="Component of the RSC chromatin remodeling complex;
DNA-binding protein involved in the synthesis of rRNA and
in transcriptional repression and activation of genes
regulated by the Target of Rapamycin (TOR) pathway"
/codon_start=1
/product="Rsc9p"
/protein_id="NP_013579.1"
/db_xref="GI:6323508"
/db_xref="SGD:S000004596"
/db_xref="GeneID:854912"
/translation="MNSLASNTPLNGTPVSEAPATSSEPVNMFETMVANPIKVSRLQS
NGVLTGPAANTKSIHYSLANFNVFQSLPKETARGVDDLTRMEMALLSGIPEEIKWSLK
KYLTYSNKAPYMISLRTLPDLLPLFKTFILPLERIVEGLNKSSICDSKAMDSLQMGLN
ALLILRNLAQDTDSVQILVKDREIKSFILFILKKFQCVATGDNKWQLYEGNATFFNEL
THYTLDLMEAISSYIAPAMKDDHYFQTLVSILNYTKDRYMVISILRSLSRLLVRSKAN
EESAADNLDHKTLSLIVSFLLLECDSELIIASLDFLYQYILPGSQRITELFKSKECSL
ILEATLPNLLSYNIATPDYHLLQKHKIRLIKRLKPPAPKEPPNLSEDLFQQLFKLNEP
LRSTAWLRCCFEPVQEAEFTQISLWRSYESKFGQPVRESGRKLLPAVEFIKNVSNAFN
NAAAIVITDPVTGKKRFVIKGIQPRFKALGIADGERESQVPISALKSKFLNDSKEITP
ARQNSIPEVKFPQELSDVSKVACTFLCLLSNDTDDGAGSAFCQRIRPLVLHKLADIPP
LTLALSEYMENTSGL"
gene complement(19060..20535)
/gene="ERG13"
/locus_tag="YML126C"
/gene_synonym="HMGS"
/db_xref="GeneID:854913"
mRNA complement(19060..20535)
/gene="ERG13"
/locus_tag="YML126C"
/gene_synonym="HMGS"
/product="hydroxymethylglutaryl-CoA synthase"
/transcript_id="NM_001182489.1"
/db_xref="GI:296146993"
/db_xref="GeneID:854913"
CDS complement(19060..20535)
/gene="ERG13"
/locus_tag="YML126C"
/gene_synonym="HMGS"
/EC_number="2.3.3.10"
/note="3-hydroxy-3-methylglutaryl-CoA (HMG-CoA) synthase,
catalyzes the formation of HMG-CoA from acetyl-CoA and
acetoacetyl-CoA; involved in the second step in mevalonate
biosynthesis"
/codon_start=1
/product="hydroxymethylglutaryl-CoA synthase"
/protein_id="NP_013580.1"
/db_xref="GI:6323509"
/db_xref="SGD:S000004595"
/db_xref="GeneID:854913"
/translation="MKLSTKLCWCGIKGRLRPQKQQQLHNTNLQMTELKKQKTAEQKT
RPQNVGIKGIQIYIPTQCVNQSELEKFDGVSQGKYTIGLGQTNMSFVNDREDIYSMSL
TVLSKLIKSYNIDTNKIGRLEVGTETLIDKSKSVKSVLMQLFGENTDVEGIDTLNACY
GGTNALFNSLNWIESNAWDGRDAIVVCGDIAIYDKGAARPTGGAGTVAMWIGPDAPIV
FDSVRASYMEHAYDFYKPDFTSEYPYVDGHFSLTCYVKALDQVYKSYSKKAISKGLVS
DPAGSDALNVLKYFDYNVFHVPTCKLVTKSYGRLLYNDFRANPQLFPEVDAELATRDY
DESLTDKNIEKTFVNVAKPFHKERVAQSLIVPTNTGNMYTASVYAAFASLLNYVGSDD
LQGKRVGLFSYGSGLAASLYSCKIVGDVQHIIKELDITNKLAKRITETPKDYEAAIEL
RENAHLKKNFKPQGSIEHLQSGVYYLTNIDDKFRRSYDVKK"
gene complement(20761..21699)
/gene="PGA3"
/locus_tag="YML125C"
/gene_synonym="NQR1"
/db_xref="GeneID:854914"
mRNA complement(20761..21699)
/gene="PGA3"
/locus_tag="YML125C"
/gene_synonym="NQR1"
/product="Pga3p"
/transcript_id="NM_001182488.1"
/db_xref="GI:296146994"
/db_xref="GeneID:854914"
CDS complement(20761..21699)
/gene="PGA3"
/locus_tag="YML125C"
/gene_synonym="NQR1"
/EC_number="1.-.-.-"
/note="Putative cytochrome b5 reductase, localized to the
plasma membrane; may be involved in regulation of
lifespan; required for maturation of Gas1p and Pho8p,
proposed to be involved in protein trafficking"
/codon_start=1
/product="Pga3p"
/protein_id="NP_013581.1"
/db_xref="GI:6323510"
/db_xref="SGD:S000004594"
/db_xref="GeneID:854914"
/translation="MSKEDIEGTNILDEPVHGIYIPAALFVVGVAITTYMSGELKILW
SLPILFMIIFVRAYSAYKRRRSLYPDRWTSLELEDQTIISKNTALYRFKLKTRLESLD
IPAGHHVAVRVPIDGKQEVRYYNPISSKLESGYLDLVVKAYVDGKVSKYFAGLNSGDT
VDFKGPIGTLNYEPNSSKHLGIVAGGSGITPVLQILNEIITVPEDLTKVSLLYANETE
NDILLKDELDEMAEKYPHFQVHYVVHYPSDRWTGDVGYITKDQMNRYLPEYSEDNRLL
ICGPDGMNNLALQYAKELGWKVNSTRSSGDDQVFVF"
gene complement(22048..23683)
/gene="TUB3"
/locus_tag="YML124C"
/db_xref="GeneID:854915"
mRNA complement(join(22048..23360,23659..23683))
/gene="TUB3"
/locus_tag="YML124C"
/product="Tub3p"
/transcript_id="NM_001182487.1"
/db_xref="GI:296146995"
/db_xref="GeneID:854915"
CDS complement(join(22048..23360,23659..23683))
/gene="TUB3"
/locus_tag="YML124C"
/note="Alpha-tubulin; associates with beta-tubulin (Tub2p)
to form tubulin dimer, which polymerizes to form
microtubules; expressed at lower level than Tub1p"
/codon_start=1
/product="Tub3p"
/protein_id="NP_013582.1"
/db_xref="GI:6323511"
/db_xref="SGD:S000004593"
/db_xref="GeneID:854915"
/translation="MREVISINVGQAGCQIGNACWELYSLEHGIKEDGHLEDGLSKPK
GGEEGFSTFFHETGYGKFVPRAIYVDLEPNVIDEVRTGRFKELFHPEQLINGKEDAAN
NYARGHYTVGREIVDEVEERIRKMADQCDGLQGFLFTHSLGGGTGSGLGSLLLENLSY
EYGKKSKLEFAVYPAPQLSTSVVEPYNTVLTTHTTLEHADCTFMVDNEAIYDICKRNL
GISRPSFSNLNGLIAQVISSVTASLRFDGSLNVDLNEFQTNLVPYPRIHFPLVSYAPI
LSKKRATHESNSVSEITNACFEPGNQMVKCDPTKGKYMANCLLYRGDVVTRDVQRAVE
QVKNKKTVQMVDWCPTGFKIGICYEPPSVIPSSELANVDRAVCMLSNTTAIADAWKRI
DQKFDLMYAKRAFVHWYVGEGMEEGEFTEAREDLAALERDYIEVGADSYAEEF"
gene complement(24037..25800)
/gene="PHO84"
/locus_tag="YML123C"
/db_xref="GeneID:854916"
mRNA complement(24037..25800)
/gene="PHO84"
/locus_tag="YML123C"
/product="Pho84p"
/transcript_id="NM_001182486.1"
/db_xref="GI:296146996"
/db_xref="GeneID:854916"
CDS complement(24037..25800)
/gene="PHO84"
/locus_tag="YML123C"
/note="High-affinity inorganic phosphate (Pi) transporter
and low-affinity manganese transporter; regulated by Pho4p
and Spt7p; mutation confers resistance to arsenate; exit
from the ER during maturation requires Pho86p; cells
overexpressing Pho84p accumulate heavy metals but do not
develop symptoms of metal toxicity"
/codon_start=1
/product="Pho84p"
/protein_id="NP_013583.1"
/db_xref="GI:6323512"
/db_xref="SGD:S000004592"
/db_xref="GeneID:854916"
/translation="MSSVNKDTIHVAERSLHKEHLTEGGNMAFHNHLNDFAHIEDPLE
RRRLALESIDDEGFGWQQVKTISIAGVGFLTDSYDIFAINLGITMMSYVYWHGSMPGP
SQTLLKVSTSVGTVIGQFGFGTLADIVGRKRIYGMELIIMIVCTILQTTVAHSPAINF
VAVLTFYRIVMGIGIGGDYPLSSIITSEFATTKWRGAIMGAVFANQAWGQISGGIIAL
ILVAAYKGELEYANSGAECDARCQKACDQMWRILIGLGTVLGLACLYFRLTIPESPRY
QLDVNAKLELAAAAQEQDGEKKIHDTSDEDMAINGLERASTAVESLDNHPPKASFKDF
CRHFGQWKYGKILLGTAGSWFTLDVAFYGLSLNSAVILQTIGYAGSKNVYKKLYDTAV
GNLILICAGSLPGYWVSVFTVDIIGRKPIQLAGFIILTALFCVIGFAYHKLGDHGLLA
LYVICQFFQNFGPNTTTFIVPGECFPTRYRSTAHGISAASGKVGAIIAQTALGTLIDH
NCARDGKPTNCWLPHVMEIFALFMLLGIFTTLLIPETKRKTLEEINELYHDEIDPATL
NFRNKNNDIESSSPSQLQHEA"
gene 26930..27862
/gene="GTR1"
/locus_tag="YML121W"
/db_xref="GeneID:854918"
mRNA 26930..27862
/gene="GTR1"
/locus_tag="YML121W"
/product="Gtr1p"
/transcript_id="NM_001182484.1"
/db_xref="GI:296146997"
/db_xref="GeneID:854918"
CDS 26930..27862
/gene="GTR1"
/locus_tag="YML121W"
/note="Cytoplasmic GTP binding protein and negative
regulator of the Ran/Tc4 GTPase cycle; component of GSE
complex, which is required for sorting of Gap1p; involved
in phosphate transport and telomeric silencing; similar to
human RagA and RagB"
/codon_start=1
/product="Gtr1p"
/protein_id="NP_013585.1"
/db_xref="GI:6323514"
/db_xref="SGD:S000004590"
/db_xref="GeneID:854918"
/translation="MSSNNRKKLLLMGRSGSGKSSMRSIIFSNYSAFDTRRLGATIDV
EHSHLRFLGNMTLNLWDCGGQDVFMENYFTKQKDHIFQMVQVLIHVFDVESTEVLKDI
EIFAKALKQLRKYSPDAKIFVLLHKMDLVQLDKREELFQIMMKNLSETSSEFGFPNLI
GFPTSIWDESLYKAWSQIVCSLIPNMSNHQSNLKKFKEIMNALEIILFERTTFLVICS
SNGENSNENHDSSDNNNVLLDPKRFEKISNIMKNFKQSCTKLKSGFKTLILNNNIYVS
ELSSNMVCFIVLKDMNIPQELVLENIKKAKEFFQ"
gene complement(28266..29807)
/gene="NDI1"
/locus_tag="YML120C"
/db_xref="GeneID:854919"
mRNA complement(28266..29807)
/gene="NDI1"
/locus_tag="YML120C"
/product="NADH-ubiquinone reductase (H(+)-translocating)
NDI1"
/transcript_id="NM_001182483.1"
/db_xref="GI:296146998"
/db_xref="GeneID:854919"
CDS complement(28266..29807)
/gene="NDI1"
/locus_tag="YML120C"
/EC_number="1.6.5.3"
/note="NADH:ubiquinone oxidoreductase; transfers electrons
from NADH to ubiquinone in the respiratory chain but does
not pump protons, in contrast to the higher eukaryotic
multisubunit respiratory complex I; phosphorylated;
involved in Mn and H2O2 induced apoptosis; upon apoptotic
stress, Ndip is activated in the mitochondria by
N-terminal cleavage, and the truncated protein
translocates to the cytoplasm to induce apoptosis; homolog
of human AMID"
/codon_start=1
/product="NADH-ubiquinone reductase (H(+)-translocating)
NDI1"
/protein_id="NP_013586.1"
/db_xref="GI:6323515"
/db_xref="SGD:S000004589"
/db_xref="GeneID:854919"
/translation="MLSKNLYSNKRLLTSTNTLVRFASTRSTGVENSGAGPTSFKTMK
VIDPQHSDKPNVLILGSGWGAISFLKHIDTKKYNVSIISPRSYFLFTPLLPSAPVGTV
DEKSIIEPIVNFALKKKGNVTYYEAEATSINPDRNTVTIKSLSAVSQLYQPENHLGLH
QAEPAEIKYDYLISAVGAEPNTFGIPGVTDYGHFLKEIPNSLEIRRTFAANLEKANLL
PKGDPERRRLLSIVVVGGGPTGVEAAGELQDYVHQDLRKFLPALAEEVQIHLVEALPI
VLNMFEKKLSSYAQSHLENTSIKVHLRTAVAKVEEKQLLAKTKHEDGKITEETIPYGT
LIWATGNKARPVITDLFKKIPEQNSSKRGLAVNDFLQVKGSNNIFAIGDNAFAGLPPT
AQVAHQEAEYLAKNFDKMAQIPNFQKNLSSRKDKIDLLFEENNFKPFKYNDLGALAYL
GSERAIATIRSGKRTFYTGGGLMTFYLWRILYLSMILSARSRLKVFFDWIKLAFFKRD
FFKGL"
gene 30611..31684
/locus_tag="YML119W"
/db_xref="GeneID:854920"
mRNA 30611..31684
/locus_tag="YML119W"
/product="hypothetical protein"
/transcript_id="NM_001182482.1"
/db_xref="GI:296146999"
/db_xref="GeneID:854920"
CDS 30611..31684
/locus_tag="YML119W"
/note="hypothetical protein; YML119W is not an essential
gene; potential Cdc28p substrate"
/codon_start=1
/product="hypothetical protein"
/protein_id="NP_013587.1"
/db_xref="GI:6323516"
/db_xref="SGD:S000004588"
/db_xref="GeneID:854920"
/translation="MSPSPSVSPRRTLNNKSSYINNSGGLVLPPTQFNLNQQPVLSFQ
QKATFDSNQQFFYYPESPTKNLRPRFNSISQVNKGVNEDHYTGGGSSNNNRPSRYTNT
MGAANTNVNSHPHHQSVSHLNSKSLKFNQTKEVSSINEIIFPSRTCTKKRYFTKPIDL
YGTRSSTSVAPKLTNSPTKSKTNFNIKKCILPRSVVTTYKLPSPVHETIDDISKKIII
LLISLKFEKNYHFLQPIQLSTNSKTRISKSLDELCGVQLTSTLRQQKQLQGNSKPVKN
LPNSNAKQRAGASVSTNANESFELSFDGKAMDRSDIFRMVDSFSIAISDEDEEDEEED
SFQQRSANNRILPAEILSNEPLK"
rep_origin 31688..31935
/note="ARS1303;
Autonomously Replicating Sequence"
/db_xref="SGD:S000118365"
gene 32334..33851
/gene="NGL3"
/locus_tag="YML118W"
/db_xref="GeneID:854921"
mRNA 32334..33851
/gene="NGL3"
/locus_tag="YML118W"
/product="Ngl3p"
/transcript_id="NM_001182481.1"
/db_xref="GI:296147000"
/db_xref="GeneID:854921"
CDS 32334..33851
/gene="NGL3"
/locus_tag="YML118W"
/EC_number="3.1.-.-"
/note="3'-5' exonuclease specific for poly-A RNAs; has a
domain similar to a magnesium-dependent endonuclease motif
in mRNA deadenylase Ccr4p; similar to Ngl1p and Ngl2p"
/codon_start=1
/product="Ngl3p"
/protein_id="NP_013588.1"
/db_xref="GI:6323517"
/db_xref="SGD:S000004587"
/db_xref="GeneID:854921"
/translation="MDSQVEGKISPSQKESSSTSGLVSPSEDGPAHQKIHRDQLSVDQ
IKKIREERAQKRQVRRNSLISQGKDPDFPTPDLQFIERPFLPINHDNSKGLTPATIQV
TQDSLDVKIMTYNTLAQTLIRRDFFPESGPALKWHKRSKVLVHELKKYRPDVVSLQEV
DYNELNFWQENFHKLGFDVIFKRHEGKTHGLLVAWNNKKFQLDNDWMLDYDNILAGNV
ISARTRTKNIALIISLYFKGITDSSSRGIIVANTHLFWHPFGVFERLRQSYLVLQKIQ
EIKACSKYNGWHSLLMGDFNTEPEEPPYLAITKRPLILKGPIRAMVECSLAYRYSKKR
NGEESDQDDEECDEKSRGEGHSDQPQNPKPESFTATKEEKALVNQLVALHNSLHVKGV
SLYGIGYGKVHPENANGSHGEPGLSNWANTWCGLLDYIFYIEGDHNQDTRQKEPLNAF
EGNNNVKIIGYLRMPCAQEMPKHSQPFEGEYASDHISLMCQIRLFFGGEKVHSLK"
gene 34243..37647
/gene="NAB6"
/locus_tag="YML117W"
/db_xref="GeneID:854922"
mRNA 34243..37647
/gene="NAB6"
/locus_tag="YML117W"
/product="Nab6p"
/transcript_id="NM_001182479.1"
/db_xref="GI:296147001"
/db_xref="GeneID:854922"
CDS 34243..37647
/gene="NAB6"
/locus_tag="YML117W"
/note="Putative RNA-binding protein that associates with
mRNAs encoding cell wall proteins in high-throughput
studies; deletion mutants display increased sensitivity to
some cell wall disrupting agents; expression negatively
regulated by cAMP"
/codon_start=1
/product="Nab6p"
/protein_id="NP_013589.1"
/db_xref="GI:6323518"
/db_xref="SGD:S000004585"
/db_xref="GeneID:854922"
/translation="MSNSNSKKPVANYAYRQQQDYNGMNAMVGNPMMYHPVDFVNGAG
QYGPSQHPAYYTNSPLPNIPPTPFDTAYGASLFPSHLLMGSPFVSSPNMQSGYNSARS
SNLKRKAYSRPVSNHNGYNGNSNSNQNNTNNGMVTPSNYYRMGRNSFSRNNNSTRNVT
HNNNKGCDTRNNSGRRTFARNNIFDDILPEMLLQRPFCINYKVLPTGDDAYRTRSLLI
ENVDHSIDLHSIVKNFVKSNTLESAYLIEGGKSDDSKDVETKNLSILISFLTKGDCLN
FYNNILQRLSEFKTFLKSEALNLKFVCLNYDPKCLPTFIESEALTENAEEADITNGST
MISASLHHNIANKDATRSIIIEFKSPVEKSDLFKKKLQFLDRSKNKRYILESIDLVNT
DVPSNQFPENYAVLTFLNISMAIEVLDYLKKYSKNLGISKCFYVSLAPLVVSSARSSV
ANIYEGKTSTHRLSVPSVTAGNNNDSNNNGNNNKSNMSGITTLNNNSSIGVSVYGHSN
MSLTSLSSSVSLNEEIDMLATKLQGVELDGTYLEINYRDYQTPTIEEHSTHLSNVKIS
KTTENSRQFSQDIPSPLPLNEHMFMNDSNQSNGAIIPQQLIATPSPVSPNLQMNQRVL
PNPITQSLEQNFNVSAKVASSMGSDIGNRTIYIGNINPRSKAEDICNVVRGGILQSIK
YIPEKKICFVTFIEAPSAVQFYANSFIDPIVLHGNMLRVGWGHYSGPLPKLISLAVTI
GASRNVYVSLPEFAFKEKFIHDPQYKKLHETLSLPDAEQLREDFSTYGDIEQINYLSD
SHCCWINFMNISSAISLVEEMNKESTVQNESGEVTLKRATEEKFGGRYKGLLINYGKD
RCGNINKNLIAGKNSRFYKKVKRPSYNIRLSKLEEKRRQNEIDEKEKAFDKPLNLESL
GISLDAHKDNGGGETGTANNTGHENESELEAENENGNETGSFGGLGLAVASSDVKRAT
SDETDYEDIFNKSSGSSDSSSDVEVIMHSPSDPEYALKSQTLRSSSQTVINSKRPVKI
EDEEEAVGMSQLNYRSSLRQAPPRAPSTLSYNHSKNNETPMQDIFTNGETANNRKKKR
GSFARHRTIPGSDVMAQYLAQVQHSTFMYAANILGASAEDNTHPDE"
gene 38196..39824
/gene="ATR1"
/locus_tag="YML116W"
/gene_synonym="SNQ1"
/db_xref="GeneID:854924"
mRNA 38196..39824
/gene="ATR1"
/locus_tag="YML116W"
/gene_synonym="SNQ1"
/product="Atr1p"
/transcript_id="NM_001182478.1"
/db_xref="GI:296147002"
/db_xref="GeneID:854924"
CDS 38196..39824
/gene="ATR1"
/locus_tag="YML116W"
/gene_synonym="SNQ1"
/note="Multidrug efflux pump of the major facilitator
superfamily; required for resistance to aminotriazole and
4-nitroquinoline-N-oxide; ATR1 has a paralog, YMR279C,
that arose from the whole genome duplication; protein
abundance increases in response to DNA replication stress"
/codon_start=1
/product="Atr1p"
/protein_id="NP_013591.1"
/db_xref="GI:6323520"
/db_xref="SGD:S000004584"
/db_xref="GeneID:854924"
/translation="MGNQSLVVLTESKGEYENETELPVKKSSRDNNIGESLTATAFTQ
SEDEMVDSNQKWQNPNYFKYAWQEYLFIFTCMISQLLNQAGTTQTLSIMNILSDSFGS
EGNSKSWLMASFPLVSGSFILISGRLGDIYGLKKMLLVGYVLVIIWSLICGITKYSGS
DTFFIISRAFQGLGIAFVLPNVLGIIGNIYVGGTFRKNIVISFVGAMAPIGATLGCLF
AGLIGTEDPKQWPWAFYAYSIAAFINFVLSIYAIPSTIPTNIHHFSMDWIGSVLGVIG
LILLNFVWNQAPISGWNQAYIIVILIISVIFLVVFIIYEIRFAKTPLLPRAVIKDRHM
IQIMLALFFGWGSFGIFTFYYFQFQLNIRQYTALWAGGTYFMFLIWGIIAALLVGFTI
KNVSPSVFLFFSMVAFNVGSIMASVTPVHETYFRTQLGTMIILSFGMDLSFPASSIIF
SDNLPMEYQGMAGSLVNTVVNYSMSLCLGMGATVETQVNSDGKHLLKGYRGAQYLGIG
LASLACMISGLYMVESFIKGRRARAAAEYDCTVA"
rep_origin 39824..40187
/note="ARS1304;
Putative replication origin, identified in multiple array
studies, not yet confirmed by plasmid-based assay"
/db_xref="SGD:S000130187"
gene complement(40187..41794)
/gene="VAN1"
/locus_tag="YML115C"
/gene_synonym="LDB13; VRG7; VRG8"
/db_xref="GeneID:854925"
mRNA complement(40187..41794)
/gene="VAN1"
/locus_tag="YML115C"
/gene_synonym="LDB13; VRG7; VRG8"
/product="Van1p"
/transcript_id="NM_001182477.1"
/db_xref="GI:296147003"
/db_xref="GeneID:854925"
CDS complement(40187..41794)
/gene="VAN1"
/locus_tag="YML115C"
/gene_synonym="LDB13; VRG7; VRG8"
/note="Component of the mannan polymerase I, which
contains Van1p and Mnn9p and is involved in the first
steps of mannan synthesis; mutants are vanadate-resistant"
/codon_start=1
/product="Van1p"
/protein_id="NP_013592.1"
/db_xref="GI:6323521"
/db_xref="SGD:S000004583"
/db_xref="GeneID:854925"
/translation="MGMFFNLRSNIKKKAMDNGLSLPISRNGSSNNIKDKRSEHNSNS
LKGKYRYQPRSTPSKFQLTVSITSLIIIAVLSLYLFISFLSGMGIGVSTQNGRSLLGS
SKSSENYKTIDLEDEEYYDYDFEDIDPEVISKFDDGVQHYLISQFGSEVLTPKDDEKY
QRELNMLFDSTVEEYDLSNFEGAPNGLETRDHILLCIPLRNAADVLPLMFKHLMNLTY
PHELIDLAFLVSDCSEGDTTLDALIAYSRHLQNGTLSQIFQEIDAVIDSQTKGTDKLY
LKYMDEGYINRVHQAFSPPFHENYDKPFRSVQIFQKDFGQVIGQGFSDRHAVKVQGIR
RKLMGRARNWLTANALKPYHSWVYWRDADVELCPGSVIQDLMSKNYDVIVPNVWRPLP
TFLGTEQPYDLNSWMESQEALALAKTLDEDDVIVEGYAEYPTWRVHLAYIRDAEGDPN
EAVDLDGVGGVSILAKAKIFRNGVQFPAFTFENHAETEAFGKMAKKMGYRVGGLPHYT
IWHIYEPSDDDLKEIASREREKRRQSE"
gene complement(42043..43575)
/gene="TAF8"
/locus_tag="YML114C"
/gene_synonym="TAF65"
/db_xref="GeneID:854926"
mRNA complement(42043..43575)
/gene="TAF8"
/locus_tag="YML114C"
/gene_synonym="TAF65"
/product="Taf8p"
/transcript_id="NM_001182476.1"
/db_xref="GI:296147004"
/db_xref="GeneID:854926"
CDS complement(42043..43575)
/gene="TAF8"
/locus_tag="YML114C"
/gene_synonym="TAF65"
/note="TFIID subunit (65 kDa), involved in RNA polymerase
II transcription initiation"
/codon_start=1
/product="Taf8p"
/protein_id="NP_013593.1"
/db_xref="GI:6323522"
/db_xref="SGD:S000004582"
/db_xref="GeneID:854926"
/translation="MTSKTSESGTGTQSTIVQLRNLPDLTEISHLEIDAPVVEILKKT
VLFQLNSLNICISNFALDELVNLVTVQMDGMFRNLHNLTLLQRRSQASQADLKLLLRE
FNLDAPSLYQQFQASEFIKSKHSTEYEKLMSWSSLAALPHNEEDEEDELNNIEEQQNE
INVLLPPSNPLEKQIPSWLPNFPPDHTYKFTPEFNHPITDLKTIKKEIVKESQESEKA
LLNLNKSLSHISSASNTPQPPGLDDEDAIEQQLEIWGNALEERKPTITEKSFNENNIE
QYAKYRVELARERVTKFEVNQLKRTKNPFLKISETLYLPESPHQSHKTIQKTIELQFR
KSMTLFMHNLPKVQKLKKEKIRMAKEERAKSLKRRQEELISQRTKREQDEGHDLELLL
NNEHARDAADDTTTPNALNNSTIVINTNAEDEDDDINLFGILGSSEDENEMSSMPAEN
LVAESEPPTMTAQDTTNTTPVAHNTTNIDATTSHSPHSTPNENAPTSPPADIATDHDI
TM"
gene 44045..44791
/gene="DAT1"
/locus_tag="YML113W"
/db_xref="GeneID:854927"
mRNA 44045..44791
/gene="DAT1"
/locus_tag="YML113W"
/product="Dat1p"
/transcript_id="NM_001182475.1"
/db_xref="GI:296147005"
/db_xref="GeneID:854927"
CDS 44045..44791
/gene="DAT1"
/locus_tag="YML113W"
/note="DNA binding protein that recognizes
oligo(dA).oligo(dT) tracts; Arg side chain in its
N-terminal pentad Gly-Arg-Lys-Pro-Gly repeat is required
for DNA-binding; not essential for viability"
/codon_start=1
/product="Dat1p"
/protein_id="NP_013594.1"
/db_xref="GI:6323523"
/db_xref="SGD:S000004581"
/db_xref="GeneID:854927"
/translation="MAKTLAQGRKPGSGRKPGKGKTLREGRKPGSGRRRRQDTGGKET
DGSQQDQESRLISSRDMEAVDALRELTHSPSSHSAHNSSAAPPPHAAAASTSLPPSLD
YTHQSFMDQQQQQQQQQQQQLLQQQRVDVVPPKPFITHKILLSSTGNSGGHVNSNYNA
DHSINHNSNHNLNSNVNVNMNFTINGSNQDPSSSFLMGPYNYLQRPFIVKPYLDLSTS
TAASNQPRTQPSPAAHITKNSDSTEKNATI"
gene 45063..45953
/gene="CTK3"
/locus_tag="YML112W"
/db_xref="GeneID:854928"
mRNA 45063..45953
/gene="CTK3"
/locus_tag="YML112W"
/product="Ctk3p"
/transcript_id="NM_001182474.1"
/db_xref="GI:296147006"
/db_xref="GeneID:854928"
CDS 45063..45953
/gene="CTK3"
/locus_tag="YML112W"
/note="Gamma subunit of C-terminal domain kinase I; CTDK-I
phosphorylates RNA polymerase II subunit Rpo21p to affect
transcription and pre-mRNA 3' end processing, and also
phosphorylates ribosomal protein Rps2p to increase
translational fidelity; protein abundance increases in
response to DNA replication stress"
/codon_start=1
/product="Ctk3p"
/protein_id="NP_013595.1"
/db_xref="GI:6323524"
/db_xref="SGD:S000004580"
/db_xref="GeneID:854928"
/translation="MDSLEARLQFIQVLKNLQKTLHKTRDSITSSSTTTPPSSQQKLN
NDPIQFYLRNYRHHYEDFHQCLFDTTMKMDPLDRLDVVIYYVRIIRNLYPHSHSNTNV
TKVLNEVLLMDIDLVFELCLPCQDWKSLTNQATCKELFLDLSKLIHYDATSVTHTPSD
TTLIDATTWYSVKTERTTKDYKESLQRTESLLKDRDLKKLAFFQQFNSDTTAINPDLQ
TQPTNANILLHRMEADRELHKRSKETSWYIERPSNDILDESEFKSLWTHFETTDSGFD
KDDYKNIKALNDIAKASYIY"
gene 46942..49704
/gene="BUL2"
/locus_tag="YML111W"
/db_xref="GeneID:854929"
mRNA 46942..49704
/gene="BUL2"
/locus_tag="YML111W"
/product="ubiquitin-ubiquitin ligase BUL2"
/transcript_id="NM_001182473.1"
/db_xref="GI:296147007"
/db_xref="GeneID:854929"
CDS 46942..49704
/gene="BUL2"
/locus_tag="YML111W"
/note="Component of the Rsp5p E3-ubiquitin ligase complex;
involved in intracellular amino acid permease sorting,
functions in heat shock element mediated gene expression,
essential for growth in stress conditions; BUL2 has a
paralog, BUL1, that arose from the whole genome
duplication"
/codon_start=1
/product="ubiquitin-ubiquitin ligase BUL2"
/protein_id="NP_013596.1"
/db_xref="GI:6323525"
/db_xref="SGD:S000004579"
/db_xref="GeneID:854929"
/translation="MTFTFSTSSRKNGRPPLKSVSTEDNIHLLRKRRQQQLSSNSTDN
SLHPNSGQTPRASDSQDDDIRSASTTNLDRLRQEREENSLEMDCTQSRLSHRANMLVD
VLPSFEMYNALHRHIPQGNVDPDRHDFPPSYQEVRTQRMTILPSNDNSVERSQLTAVP
GSENACNNATAHSLTNLHPLQTQHLTINSTRSGGQSLHSSSDTNISQIPFEDDLNDSD
NIFIDKLYTLPKLSTPIEIDIRITKTASIPHERPEEQSILKEYTSGDIIHGYCLIENR
SSQPLKFEMFYVTLEAYISVIDRQKGKRTLKRFLRMVDLSASWSYTNITPSTGINIVP
GERDFDDAIIGLSNSRELKPNTKYKKFFMFKLPTQLLDVTCKQEQFSHCLLPPSFGID
KYKNNCKYSGIKVNSVLGCGHLGTKGSPILTLDMADDNLSINYTIDAKIVGKDKRTSK
LNIMKEKEYNLRVMPFPFAGVTNQQNEKTCLRQLKNLESLIEDRFEALNKIFKKLELN
EAISNVDIHDTDISGTLDGNEDLDSDEILRRKLDQLHINNRIDDTASQSPSYDSKNMA
PKENLVETELRYKFKNKNKSNSSLFSHFLSSSETGSSSTGPHVYNSGLIVLSVKKPQS
TLPYWSPSLLRKTNKFEAKSEQEKENWQRLMGMLPEGVKTPLTKLDVHLTCIQSNNSA
GHKPPEISSVTTEFVVITAKSDNSIPIKFCTELLMNENRLNKLKTKFLTYQKKVHEYR
KKFEENHAKLNELYNRNRDHFTPKELLFTNFISDQINNDIDSLAGLKVNIIDLHDIFK
KQIHTFEEENEDIISKKGSSNPPSASSSNNNFLQATFSNGASTATKFTQQIVHEWEKV
KPLQYKRDVTVNLKLNPNIKETLVPNLETCLCCRFYCVRVNIKFDNHLGSMKVDIPVD
VKKLQI"
gene complement(50031..50954)
/gene="COQ5"
/locus_tag="YML110C"
/gene_synonym="DBI56"
/db_xref="GeneID:854930"
mRNA complement(50031..50954)
/gene="COQ5"
/locus_tag="YML110C"
/gene_synonym="DBI56"
/product="2-hexaprenyl-6-methoxy-1,4-benzoquinone
methyltransferase"
/transcript_id="NM_001182472.1"
/db_xref="GI:296147008"
/db_xref="GeneID:854930"
CDS complement(50031..50954)
/gene="COQ5"
/locus_tag="YML110C"
/gene_synonym="DBI56"
/EC_number="2.1.1.-"
/note="2-hexaprenyl-6-methoxy-1,4-benzoquinone
methyltransferase, involved in ubiquinone (Coenzyme Q)
biosynthesis; localizes to the matrix face of the
mitochondrial inner membrane in a large complex with other
ubiquinone biosynthetic enzymes"
/codon_start=1
/product="2-hexaprenyl-6-methoxy-1,4-benzoquinone
methyltransferase"
/protein_id="NP_013597.1"
/db_xref="GI:6323526"
/db_xref="SGD:S000004578"
/db_xref="GeneID:854930"
/translation="MLISSRIVRSSLVNVPLRLSRCFTQAHRACKEEEVNSPLSSAAE
QPEQKYTHFGSKTVLKSTKQKLVGDVFSSVANRYDLMNDVMSLGIHRLWKDHFINKLD
AGKRPNSTTPLNFIDVAGGSGDIAFGLLDHAESKFGDTESTMDIVDINPDMLKEGEKR
AMEQGKYFKDPRVRFLVSNGEKLEEIDSDSKDIYTVSFGIRNFTDIQKGLNTAYRVLK
PGGIFYCLEFSKIENPLMDFAYQQWAKVLPVMGSMIANDYDSYQYLVESIERFPDQET
FKSMIEKAGFKSAGYESLTFGICAIHWGIKV"
gene 51640..54468
/gene="ZDS2"
/locus_tag="YML109W"
/gene_synonym="CES4"
/db_xref="GeneID:854931"
mRNA 51640..54468
/gene="ZDS2"
/locus_tag="YML109W"
/gene_synonym="CES4"
/product="Zds2p"
/transcript_id="NM_001182471.1"
/db_xref="GI:296147009"
/db_xref="GeneID:854931"
CDS 51640..54468
/gene="ZDS2"
/locus_tag="YML109W"
/gene_synonym="CES4"
/note="Protein with a role in regulating Swe1p-dependent
polarized growth; involved in maintenance of Cdc55p in the
cytoplasm where it promotes mitotic entry; interacts with
silencing proteins at the telomere; implicated in the
mitotic exit network through regulation of Cdc14p
localization; paralog of Zds1p"
/codon_start=1
/product="Zds2p"
/protein_id="NP_013598.1"
/db_xref="GI:6323527"
/db_xref="SGD:S000004577"
/db_xref="GeneID:854931"
/translation="MVLMEDMQNKDGHNTVENSSGGTDSNNNIQMRRMRKTQLSKKEL
FEKRKSDVLIAAKSLDTEIQNVKNLKRLSIGSMDLVIDPELEFKVNSRNSYSSDSSKE
SLQESLHEENIIRSEQKEEQGSEDNDAYEEGDATNVDDSIDITQTEYLHDEETLEKEK
IIRNASSSTSSSARVTSRNRRLSGVKTLAHDVVLDVENDHDSKMVDLTQNLLWVPADQ
HPNVKPENYLELIQDTLQNIQISTNQDIDENKLELGNNHVISNRKRTGSVVRRPSRLK
TSYTKFDDEPPLADKPQEGEIQVDKRISSSDIKTIRSVSLKEITEELTKISNNAGLTD
SDAVTLARSLSMSGSFTNESLHLNGNHTENDNEFASNMFNETGLTIPERSSLRRSKFN
TYKIRLEGSSLPQAVKLNSLMNIQTNDNRRSASSPASYTQVPQEQASLNDFHEIFDHY
RRTSTDWSTENEKYVDSTNYYSDEEDLTHASISQESSLLSTDSSNNSVLIKPHNTGSM
ISEKLDQHVSSSEKSNTNNSEANHGWSWLNSSNGSLNANEQTYQQLTDDEDDEECVDN
EKADFVNLSVSRRAKSTKRASERINHSKNRHSPIFQIHSEEAKSVVITPSVVSSSESQ
PSKPTAPAVVEKKVELPTDTQASTHKKNSLEKRLAKLFKRKQHNGTCKSDVKVIKKSV
KKELKKKASHSSLSKFRKSPKKKPQEAEVERPSSPTKTITTEDIDTASVIEPEVRSSN
ASTLLPDSHTSHSSEFVVETISELDGDDSFDISGGDVNYDVEVHSSISRDTTAGLEED
IGAEREDNTSPTAPQISTLPPRKLTFEDVVKPDYSNAPIKFTDSAFGFPLPMITNSTV
IMFDHRLGINVERAIYRLSHLKLSDPGRELRQQVLLSNFMYSYLNLVNHTLYMEQVGT
GDIAFNGDSALGMMDKNDSDGTILIPDI"
gene 54793..55110
/locus_tag="YML108W"
/db_xref="GeneID:854863"
mRNA 54793..55110
/locus_tag="YML108W"
/product="hypothetical protein"
/transcript_id="NM_001182470.1"
/db_xref="GI:296147010"
/db_xref="GeneID:854863"
CDS 54793..55110
/locus_tag="YML108W"
/note="hypothetical protein; structure defines a new
subfamily of the split beta-alpha-beta sandwiches; green
fluorescent protein (GFP)-fusion protein localizes to the
cytoplasm and nucleus; YML108W is not an essential gene;
relative distribution to the nucleus increases upon DNA
replication stress"
/codon_start=1
/product="hypothetical protein"
/protein_id="NP_013599.1"
/db_xref="GI:6323528"
/db_xref="SGD:S000004576"
/db_xref="GeneID:854863"
/translation="MSKSNTYRMLVLLEDDTKINKEDEKFLKGKPGKMHEFVDELILP
FNVDELDELNTWFDKFDAEICIPNEGHIKYEISSDGLIVLMLDKEIEEVVEKVKKFVE
ENN"
gene complement(55265..56269)
/gene="PML39"
/locus_tag="YML107C"
/db_xref="GeneID:854864"
mRNA complement(55265..56269)
/gene="PML39"
/locus_tag="YML107C"
/product="Pml39p"
/transcript_id="NM_001182469.1"
/db_xref="GI:296147011"
/db_xref="GeneID:854864"
CDS complement(55265..56269)
/gene="PML39"
/locus_tag="YML107C"
/note="Protein required for nuclear retention of unspliced
pre-mRNAs along with Mlp1p and Pml1p; anchored to nuclear
pore complex via Mlp1p and Mlp2p; found with the subset of
nuclear pores farthest from the nucleolus; may interact
with ribosomes"
/codon_start=1
/product="Pml39p"
/protein_id="NP_013600.2"
/db_xref="GI:37362681"
/db_xref="SGD:S000004575"
/db_xref="GeneID:854864"
/translation="MEKDALEVRLKSIRHSLDKNTKLLPGKYRNTLGERLITKWRYKK
KSHNGSSMLPEKCKSHVQLYDDLVQESSKHFVGFRLHDLRALLKRICSIQNYTRHVLI
EWDVRWVNPLTLASKGWEPYQSASQSQVPFKCCCCHAIMTIPLLKNGDDVADYTMKLN
EKIWNSNIIGNHLQKCPWRENQVDLNKEYYLSSQNLIREIERIHTEIDRIVSGSNEFS
LKRNSSRIFHYLSEKEIQKLAFFFDCKDYSLVGLLLLGYTKFQKDDLVQCTACFHRAS
LKKLEYTEFNGHALWCRYYNKELLPTMLLELIGKEDKLITKLGVGERLNKLEAVLQTL
"
gene 56773..57453
/gene="URA5"
/locus_tag="YML106W"
/gene_synonym="PYR5"
/db_xref="GeneID:854865"
mRNA 56773..57453
/gene="URA5"
/locus_tag="YML106W"
/gene_synonym="PYR5"
/product="orotate phosphoribosyltransferase URA5"
/transcript_id="NM_001182468.1"
/db_xref="GI:296147012"
/db_xref="GeneID:854865"
CDS 56773..57453
/gene="URA5"
/locus_tag="YML106W"
/gene_synonym="PYR5"
/EC_number="2.4.2.10"
/note="Major orotate phosphoribosyltransferase (OPRTase)
isozyme that catalyzes the fifth enzymatic step in de novo
biosynthesis of pyrimidines, converting orotate into
orotidine-5'-phosphate; minor OPRTase encoded by URA10"
/codon_start=1
/product="orotate phosphoribosyltransferase URA5"
/protein_id="NP_013601.1"
/db_xref="GI:6323530"
/db_xref="SGD:S000004574"
/db_xref="GeneID:854865"
/translation="MPIMLEDYQKNFLELAIECQALRFGSFKLKSGRESPYFFNLGLF
NTGKLLSNLATAYAIAIIQSDLKFDVIFGPAYKGIPLAAIVCVKLAEIGGSKFQNIQY
AFNRKEAKDHGEGGIIVGSALENKRILIIDDVMTAGTAINEAFEIISNAKGQVVGSII
ALDRQEVVSTDDKEGLSATQTVSKKYGIPVLSIVSLIHIITYLEGRITAEEKSKIEQY
LQTYGASA"
gene complement(57866..58687)
/gene="SEC65"
/locus_tag="YML105C"
/db_xref="GeneID:854866"
mRNA complement(57866..58687)
/gene="SEC65"
/locus_tag="YML105C"
/product="Sec65p"
/transcript_id="NM_001182467.1"
/db_xref="GI:296147013"
/db_xref="GeneID:854866"
CDS complement(57866..58687)
/gene="SEC65"
/locus_tag="YML105C"
/note="Subunit of the signal recognition particle (SRP),
involved in protein targeting to the ER; interacts with
Srp54p; homolog of mammalian SRP19"
/codon_start=1
/product="Sec65p"
/protein_id="NP_013602.1"
/db_xref="GI:6323531"
/db_xref="SGD:S000004573"
/db_xref="GeneID:854866"
/translation="MPRLEEIDDFNDIDDLDMELAELDPSLRTPIAPKITPKVVRSQD
QENPAFLPGTNNNSNSNNNSSNEKEQLSFINPKTGKVERSEAISKKDLEEVKRFQVLY
PCYFDINRSHKEGRRVPKELAVENPLAKTMADAVRELGILCIFEGEKCHPQDFGNPGR
IRVLFKENGQLIGAATKFKGGKRQLMKAVGEYMKRHPTTIESLREIPYGPDFDNIEFK
KIPRVKGFKMNEIVPLHSPFLMGHPMTKSVYETPKITAAEKSFKPPKNKYKVVRR"
gene complement(58939..62322)
/gene="MDM1"
/locus_tag="YML104C"
/db_xref="GeneID:854867"
mRNA complement(58939..62322)
/gene="MDM1"
/locus_tag="YML104C"
/product="Mdm1p"
/transcript_id="NM_001182466.1"
/db_xref="GI:296147014"
/db_xref="GeneID:854867"
CDS complement(58939..62322)
/gene="MDM1"
/locus_tag="YML104C"
/note="Intermediate filament protein, required for nuclear
and mitochondrial transmission to daughter buds; contains
a Phox homology (PX) domain and specifically binds
phosphatidylinositol 3-phosphate (PtdIns-3-P)"
/codon_start=1
/product="Mdm1p"
/protein_id="NP_013603.1"
/db_xref="GI:6323532"
/db_xref="SGD:S000004572"
/db_xref="GeneID:854867"
/translation="MPKFPQFRLILVLFYLISMIQWSVITFSLGFFLNVCIFAYFVFF
KSLPDLPKPQPRFVDIVPESSNTVDVDKELKSVEGLIQDGNAQIGKELESIVNLIIKD
FVQPWFTKIDKNSDAEFLKVIKWRLLQTLLVVKDKLMKNDSASLIVLKLLPIFNKHFS
TFCDAREAVLSDLTLERHKSANIDLQIAVEFNKNYKIHKSLSLKPNALQKEIEKSIRK
TVIGLLPHLFDNDELDSLLVFTLMTEVLTTCIISPLIFKFTDPDSWNLRIVSLSQNYF
EEKHKVHKIRRMLSKELQDHRKVMNDVANKDVGEPSSEKLELNAEYTGKQFEHYLNQL
DSLLDLSDIKYVAYSLALKIYQLKENEHLTKENLKYKKRLLLSLNLIESKLSFPGSEI
DTASKKLAREANYPDLNMDNGIVLKEMASFLTSITLKDIVDDSEFLPFFESFLGSVPE
TQGSTFLEYSQTIESFKNPLEDATSEDIISGYSGISTMQLQEISSKFFHNNNLQNMKL
LDEGLVKNIILFRNSFQINNDEDTFILARKSVLLLQTEAIKYLDDRFLPLFKKTPSFL
KMLSTSHIISTDIYAHFLSRIGGVNNPEQNKIIKDNVKTDFMNPVRIFANPGITDALD
NIVNGSGSKPHKSRISSNPRYSQLFGSENDNIFKDKLFDDENDNTSEISVVEDQLDHP
RNMEKVSVSSGNSGLNPSQFYGSNNFRDNIASLTISIDQIEKELELLRHLILKADLTN
NQMQLKILKKSQRTLLKELEMKELLKQQYMVQENGNSLFRKTKIYIRSYFSENSSNGL
KEITYYIINIHHFNNGQVSSWDMARRYNEFFELNTYLKKNFRDLMRQLQDLFPSKVKM
SLKYHVTKTLLYEERKQKLEKYLRELLSISEICEDNIFRRFLTDPTPFKLNKEYMHDD
ILEEPLHEPIGSSNSTSNSSSVVDLQSSEDGGELNFYEDERHFFTDSGYPFYSQNKSF
VKQICDLFISLFALNKANAGWLRGRAIITVLQQLLGSTIEKYIKVSIQKLRSEDQVFE
AIVTFKNMLWGDNGLFERKRNETAEATRSEGERLRTEQLALTSLQRLFADTCGRVVGL
RDSHEAAGRVHAMLQNPYLNASLLLEALDAILLDIICND"
gene complement(62582..67549)
/gene="NUP188"
/locus_tag="YML103C"
/db_xref="GeneID:854868"
mRNA complement(62582..67549)
/gene="NUP188"
/locus_tag="YML103C"
/product="Nup188p"
/transcript_id="NM_001182465.1"
/db_xref="GI:296147015"
/db_xref="GeneID:854868"
CDS complement(62582..67549)
/gene="NUP188"
/locus_tag="YML103C"
/note="Subunit of the inner ring of the nuclear pore
complex (NPC); contributes to NPC organization and
nucleocytoplasmic transport; homologous to human NUP188"
/codon_start=1
/product="Nup188p"
/protein_id="NP_013604.1"
/db_xref="GI:6323533"
/db_xref="SGD:S000004571"
/db_xref="GeneID:854868"
/translation="MATPSFGNSSPQLTFTHVANFMNDAAADVSAVDAKQLAQIRQFL
KANKTNLIESLNTIRQNVTSSGDHNKLRSTIANLLQINVDNDPFFAQSEDLSHAVEFF
MSERSSRLHIVYSLLVNPDIDLETYSFIDNDRFNVVGKLISIISSVIQNYDIITASSL
AHDYNNDQDMFTIVSLVQLKKFSDLKFILQILQILNLMILNTKVPVDIVNQWFLQYQN
QFVEFCRNINSTDKSIDTSSLQLYKFQNFQDLSYLSETLISRISSLFTITTILILGLN
TSIAQFDIQSPLYMDTETFDTVNSALENDVATNIVNEDPIFHPMIHYSWSFILYYRRA
LQSSESFDDSDITKFALFAESHDVLQKLNTLSEILSFDPVYTTVITVFLEFSLNFIPI
TASTSRVFAKIISKAPEQFIENFLTNDTFEKKLSIIKAKLPLLNESLIPLINLALIDT
EFANFELKDICSFAVTKSSLNDLDYDLIADTITNSSSSSDIIVPDLIELKSDLLVAPP
LENENSNCLLSIPKSTKGKILTIKQQQQQQQQQNGQQPPTTSNLIIFLYKFNGWSLVG
RILQNLLHSYMEKGTQLDDLQHELMISIIKLVTNVVDPKTSIEKSSEILSYLSNSLDT
SASTINGASIIQVIFEIFEISLQRKDYTSIVQCCEFMTMLTPNYLHLVSSYLNKSDLL
DKYGKTGLSNMILGSVELSTGDYTFTIQLLKLTKVFIRESLSLKNIHISKRSKIDIIN
KLILHAIHIFESYYNWKYNNFLQKFEIAFHLTLIFYDVLHDVFTINPHQKDQLIISSS
ANKLLQLFLTPMDSIDLAPNTLTNILISPLNTTTKILGDKILGNLYSKVMNNSFKLCT
LLIAIRGSNRDLKPSNLEKLLFINSSKLVDVYTLPSYVHFKVQIIELLSYLVEAPWND
DYPFLLSFLGEAKSMAFLKEVLSDLSSPVQDWNLLRSLYIFFTTLLESKQDGLSILFL
TGQFASNKKINDESSIDKKSSILTVLQKNSLLLDSTPEEVSCKLLETITYVLNTWTNS
KIFIKDPKFVNSLLAKLKDSKKLFQKKENLTRDETVSLIKKYKLISRIVEIFALCIYN
STDSNSEILNFLNQEDLFELVHHFFQIDGFNKTFHDELNLKFKEKWPSLELQSFQKIP
LSRINENENFGYDIPLLDIVLKADRSWNEPSKSQTNFKEEITDASLNLQYVNYEISTA
KAWGALITTFVKRSTVPLNDGFVDLVEHFLKLNIDFGSDKQMFTQIYLERIELSFYIL
YSFKLSGKLLKEEKIIELMNKIFTIFKSGEIDFIKNIGKSLKNNFYRPLLRSVLVLLE
LVSSGDRFIELISDQLLEFFELVFSKGVYLILSEILCQINKCSTRGLSTDHTTQIVNL
EDNTQDLLLLLSLFKKITNVNPSKNFNVILASSLNEVGTLKVILNLYSSAHLIRINDE
PILGQITLTFISELCSIEPIAAKLINSGLYSVLLESPLSVAIQQGDIKPEFSPRLHNI
WSNGLLSIVLLLLSQFGIKVLPETCLFVSYFGKQIKSTIYNWGDNKLAVSSSLIKETN
QLVLLQKMLNLLNYQELFIQPKNSDDQQEAVELVIGLDSEHDKKRLSAALSKFLTHPK
YLNSRIIPTTLEEQQQLEDESSRLEFVKGISRDIKALQDSLFKDV"
gene complement(67768..67938)
/locus_tag="snR85"
/db_xref="GeneID:9164957"
ncRNA complement(67768..67938)
/locus_tag="snR85"
/ncRNA_class="snoRNA"
/product="SNR85"
/note="H/ACA box small nucleolar RNA (snoRNA); predicted
to guide pseudouridylation of small subunit (SSU) rRNA at
position U1181"
/db_xref="SGD:S000081376"
/db_xref="GeneID:9164957"
gene 68294..69700
/gene="CAC2"
/locus_tag="YML102W"
/db_xref="GeneID:854869"
mRNA 68294..69700
/gene="CAC2"
/locus_tag="YML102W"
/product="Cac2p"
/transcript_id="NM_001182464.1"
/db_xref="GI:296147016"
/db_xref="GeneID:854869"
CDS 68294..69700
/gene="CAC2"
/locus_tag="YML102W"
/note="Subunit of chromatin assembly factor I (CAF-1),
with Rlf2p and Msi1p; chromatin assembly by CAF-1 is
important for multiple processes including silencing at
telomeres, mating type loci, and rDNA; maintenance of
kinetochore structure; deactivation of the DNA damage
checkpoint after DNA repair; and chromatin dynamics during
transcription"
/codon_start=1
/product="Cac2p"
/protein_id="NP_013605.1"
/db_xref="GI:6323534"
/db_xref="SGD:S000004570"
/db_xref="GeneID:854869"
/translation="MEASHLQIYWHDSQPVYSLTFQKNSANDKLFTAGGDNKVRIWKL
NRDENGQNGGVRKIESLDFLGSLTHHEQAINVIRFNSKGDVLASAGDDGQVLLWKQED
PNTQQESVVRPFGMDAETSEADENKEKWVVWKRLRGGSGATAAAEIYDLAWSPDNRNI
VVACMDNSIRLFDVGAGMLVCGQSDHGHYVQGVAWDPLNQFILSQSADRSLHVYGVIL
SSAGVVTGLKLRSKIAKAELPCPGDVLRTNYLFHNETLPSFFRRCSISPCGGLVVIPS
GVYKVAGDEVANCVYVYTRSGILNSAGGVKNRPAIRIPSLKKPALMAAFSPVFYETCQ
KSVLKLPYKLVFAIATTNEVLVYDTDVLEPLCVVGNIHYSPITDLAWSEDGSTLLISS
TDGFCSYVSIDTETQFGSRIEPPAMHAEPLDTDESAVAAKNQREAGGIVNMLPVKKIP
CNSSDSKKRRIHPTPVDL"
gene complement(69735..70088)
/gene="CUE4"
/locus_tag="YML101C"
/db_xref="GeneID:854871"
mRNA complement(69735..70088)
/gene="CUE4"
/locus_tag="YML101C"
/product="Cue4p"
/transcript_id="NM_001182462.1"
/db_xref="GI:296147017"
/db_xref="GeneID:854871"
CDS complement(69735..70088)
/gene="CUE4"
/locus_tag="YML101C"
/note="hypothetical protein; has a CUE domain that binds
ubiquitin, which may facilitate intramolecular
monoubiquitination"
/codon_start=1
/product="Cue4p"
/protein_id="NP_013607.1"
/db_xref="GI:6323536"
/db_xref="SGD:S000004568"
/db_xref="GeneID:854871"
/translation="MDGSTIVFILTMVCLFVYTVKHRGAKQVPSRTVQDAKPAPSVAT
NDPSPEPVPSAPEERVARLNRHGSDRKRAVNSDMVEIVMTMAPHVPQEKVVQDLRNTG
SIEHTMENIFAGKLD"
gene 70138..70311
/locus_tag="YML100W-A"
/db_xref="GeneID:1466496"
mRNA 70138..70311
/locus_tag="YML100W-A"
/product="hypothetical protein"
/transcript_id="NM_001184612.1"
/db_xref="GI:296147018"
/db_xref="GeneID:1466496"
CDS 70138..70311
/locus_tag="YML100W-A"
/note="hypothetical protein; identified by gene-trapping,
microarray-based expression analysis, and genome-wide
homology searching"
/codon_start=1
/product="hypothetical protein"
/protein_id="NP_878138.1"
/db_xref="GI:33438850"
/db_xref="SGD:S000028688"
/db_xref="GeneID:1466496"
/translation="MYKCVPSYYSKAGTIVVTYCEISALLVSLKNRVQGKRGETEGQI
EISRKAGHPAPAF"
gene 70624..73920
/gene="TSL1"
/locus_tag="YML100W"
/db_xref="GeneID:854872"
mRNA 70624..73920
/gene="TSL1"
/locus_tag="YML100W"
/product="Tsl1p"
/transcript_id="NM_001182460.1"
/db_xref="GI:296147019"
/db_xref="GeneID:854872"
CDS 70624..73920
/gene="TSL1"
/locus_tag="YML100W"
/note="Large subunit of trehalose 6-phosphate
synthase/phosphatase complex; Tps1p-Tps2p complex converts
uridine-5'-diphosphoglucose and glucose 6-phosphate to
trehalose; similar to Tps3p and may share function; mutant
has aneuploidy tolerance; protein abundance increases in
response to DNA replication stress"
/codon_start=1
/product="Tsl1p"
/protein_id="NP_013608.1"
/db_xref="GI:6323537"
/db_xref="SGD:S000004566"
/db_xref="GeneID:854872"
/translation="MALIVASLFLPYQPQFELDTSLPENSQVDSSLVNIQAMANDQQQ
QRALSNNISQESLVAPAPEQGVPPAISRSATRSPSAFNRASSTTNTATLDDLVSSDIF
MENLTANATTSHTPTSKTMLKPRKNGSVERFFSPSSNIPTDRIASPIQHEHDSGSRIA
SPIQQQQQDPTTNLLKNVNKSLLVHSLLNNTSQTSLEGPNNHIVTPKSRAGNRPTSAA
TSLVNRTKQGSASSGSSGSSAPPSIKRITPHLTASAAKQRPLLAKQPSNLKYSELADI
SSSETSSQHNESDPDDLTTAPDEEYVSDLEMDDAKQDYKVPKFGGYSNKSKLKKYALL
RSSQELFSRLPWSIVPSIKGNGAMKNAINTAVLENIIPHRHVKWVGTVGIPTDEIPEN
ILANISDSLKDKYDSYPVLTDDDTFKAAYKNYCKQILWPTLHYQIPDNPNSKAFEDHS
WKFYRNLNQRFADAIVKIYKKGDTIWIHDYHLMLVPQMVRDVLPFAKIGFTLHVSFPS
SEVFRCLAQREKILEGLTGADFVGFQTREYARHFLQTSNRLLMADVVHDEELKYNGRV
VSVRFTPVGIDAFDLQSQLKDGSVMQWRQLIRERWQGKKLIVCRDQFDRIRGIHKKLL
AYEKFLVENPEYVEKSTLIQICIGSSKDVELERQIMIVVDRINSLSTNISISQPVVFL
HQDLDFSQYLALSSEADLFVVSSLREGMNLTCHEFIVCSEDKNAPLLLSEFTGSASLL
NDGAIIINPWDTKNFSQAILKGLEMPFDKRRPQWKKLMKDIINNDSTNWIKTSLQDIH
ISWQFNQEGSKIFKLNTKTLMEDYQSSKKRMFVFNIAEPPSSRMISILNDMTSKGNIV
YIMNSFPKPILENLYSRVQNIGLIAENGAYVSLNGVWYNIVDQVDWRNDVAKILEDKV
ERLPGSYYKINESMIKFHTENAEDQDRVASVIGDAITHINTVFDHRGIHAYVYKNVVS
VQQVGLSLSAAQFLFRFYNSASDPLDTSSGQITNIQTPSQQNPSDQEQQPPASPTVSM
NHIDFACVSGSSSPVLEPLFKLVNDEASEGQVKAGHAIVYGDATSTYAKEHVNGLNEL
FTIISRIIED"
gene complement(74398..77040)
/gene="ARG81"
/locus_tag="YML099C"
/gene_synonym="ARGR2"
/db_xref="GeneID:854874"
mRNA complement(74398..77040)
/gene="ARG81"
/locus_tag="YML099C"
/gene_synonym="ARGR2"
/product="Arg81p"
/transcript_id="NM_001182459.1"
/db_xref="GI:296147020"
/db_xref="GeneID:854874"
CDS complement(74398..77040)
/gene="ARG81"
/locus_tag="YML099C"
/gene_synonym="ARGR2"
/note="Zinc-finger transcription factor of the
Zn(2)-Cys(6) binuclear cluster domain type, involved in
the regulation of arginine-responsive genes; acts with
Arg80p and Arg82p"
/codon_start=1
/product="Arg81p"
/protein_id="NP_013610.1"
/db_xref="GI:6323539"
/db_xref="SGD:S000004565"
/db_xref="GeneID:854874"
/translation="MGISSKNGPKKMGRAKTFTGCWTCRGRKVKCDLRHPHCQRCEKS
NLPCGGYDIKLRWSKPMQFDPYGVPIPQNSPATTTNLSGSVDEPQYQRRNIDFVRYDE
EYVYHEDMDDELTMLHTPPIEKISDNKTWIIKKFGVFKGTDKIDKQYAPRKKRNRKRV
AKSLESSASISLSSLPSSSTISFPIRHIEDKLRNKGHVKTGILSANDGVPPTPNLLDY
DWNNLNITGYEWISSELRDDALLSAVTLQGHHLGHTQPQEISLEENSNVVSGEEHVNA
KEHGCAFEADNQGSSTLPNKAASANDKLYQQNLKLLFQKNSSNSEEPDPQALIDDVFV
NIEPRSLPASDLNKITLAPPNEESRMPKSMLELTSYSSDLPPELVDIIPKTDLTVHGL
ARFLLNHYFNNVADKMTVVVLEKNPWKTLYFPRALMALGDLAGLGQSSNSRNALLNAL
LAVSCFHLQSKYPRNYKLQKYFLGLGIELRNQASNFLRLCLNTKSSIPEKYKDVLTAI
LSMNSIDVVWGTMADCQDHLALCEDFVESRMKLRPNISEKTKTLHRIFSFLKLIQDST
ALDKVRAKEIVILPSEEDDNYKPLDTSNATTSSSEPRVDVVQEGLFREALNENDGKIH
IEFVKEPITNVSADSTPSSTTPPIFTNIATESYYNKSDISKLVSKTDENIIGTDSLYG
LPNSLILLFSDCVRIVRHNEYYNLTYLPVPRKFNELSLNFEKRLLKWKSEWNFHQENS
EGKSFINSTAEALYHHTMSFYFSLIIYYFTMARSLNCQFLQNYVAKVLDHLNAMEELV
DQKKVKIVPLIWQGFMAGCACTDENRQQEFRRWAAKLAESGVGSYWGARQVMLEVWRR
RKEDEPGDNWYSVYKDWEMNLMLS"
gene 77267..77770
/gene="TAF13"
/locus_tag="YML098W"
/gene_synonym="FUN81; TAF19"
/db_xref="GeneID:854875"
mRNA 77267..77770
/gene="TAF13"
/locus_tag="YML098W"
/gene_synonym="FUN81; TAF19"
/product="Taf13p"
/transcript_id="NM_001182458.1"
/db_xref="GI:296147021"
/db_xref="GeneID:854875"
CDS 77267..77770
/gene="TAF13"
/locus_tag="YML098W"
/gene_synonym="FUN81; TAF19"
/note="TFIID subunit (19 kDa), involved in RNA polymerase
II transcription initiation, similar to histone H4 with
atypical histone fold motif of Spt3-like transcription
factors"
/codon_start=1
/product="Taf13p"
/protein_id="NP_013611.1"
/db_xref="GI:6323540"
/db_xref="SGD:S000004564"
/db_xref="GeneID:854875"
/translation="MSRKLKKTNLFNKDVSSLLYAYGDVPQPLQATVQCLDELVSGYL
VDVCTNAFHTAQNSQRNKLRLEDFKFALRKDPIKLGRAEELIATNKLITEAKKQFNET
DNQNSLKRYREEDEEGDEMEEDEDEQQVTDDDEEAAGRNSAKQSTDSKATKIRKQGPK
NLKKTKK"
gene complement(78335..79690)
/gene="VPS9"
/locus_tag="YML097C"
/gene_synonym="VPL31; VPT9"
/db_xref="GeneID:854876"
mRNA complement(78335..79690)
/gene="VPS9"
/locus_tag="YML097C"
/gene_synonym="VPL31; VPT9"
/product="Vps9p"
/transcript_id="NM_001182457.1"
/db_xref="GI:296147022"
/db_xref="GeneID:854876"
CDS complement(78335..79690)
/gene="VPS9"
/locus_tag="YML097C"
/gene_synonym="VPL31; VPT9"
/note="A guanine nucleotide exchange factor involved in
vesicle-mediated vacuolar protein transport; specifically
stimulates the intrinsic guanine nucleotide exchange
activity of Vps21p/Rab5: similar to mammalian ras
inhibitors; binds ubiquitin"
/codon_start=1
/product="Vps9p"
/protein_id="NP_013612.1"
/db_xref="GI:6323541"
/db_xref="SGD:S000004563"
/db_xref="GeneID:854876"
/translation="MTDDEKREILKEFDPFSQLEQANGNPDKDVKFKKDDPNRAAAEE
TNRDISAQDKGDEEPFYDFQIFIKQLQTPGADPLVKYTKSFLRNFLAQRLLWTVSEEI
KLISDFKTFIYDKFTLYEPFRSLDNSKMRNAKEGMEKLIMGKLYSRCFSPSLYEILQK
PLDDEHMKDLTNDDTLLEKIRHYRFISPIMLDIPDTMPNARLNKFVHLASKELGKINR
FKSPRDKMVCVLNASKVIFGLLKHTKLEQNGADSFIPVLIYCILKGQVRYLVSNVNYI
ERFRSPDFIRGEEEYYLSSLQAALNFIMNLTERSLTIEDHEDFEEAYQRNFKQLAEEK
EEEEKKKQLEIPDELQPNGTLLKPLDEVTNIVISKFNELFSPIGEPTQEEALKSEQSN
KEEDVSSLIKKIEENERKDTLNTLQNMFPDMDPSLIEDVCIAKKSRIGPCVDALLSLS
E"
gene 79909..81486
/locus_tag="YML096W"
/db_xref="GeneID:854877"
mRNA 79909..81486
/locus_tag="YML096W"
/product="putative asparagine synthase"
/transcript_id="NM_001182456.1"
/db_xref="GI:296147023"
/db_xref="GeneID:854877"
CDS 79909..81486
/locus_tag="YML096W"
/note="hypothetical protein with similarity to asparagine
synthetases; green fluorescent protein (GFP)-fusion
protein localizes to the cytoplasm; YML096W is not an
essential gene and partially overlaps the verified gene
RAD10"
/codon_start=1
/product="putative asparagine synthase"
/protein_id="NP_013613.1"
/db_xref="GI:6323542"
/db_xref="SGD:S000004562"
/db_xref="GeneID:854877"
/translation="MCGILLHYCPNNNYLNDELIEFPEGTEFGDTTCTNESSIFNKII
PYIAARGPNYSSLRAVKAYRISWFSSVLSLRQPFTKQSINVDDRYFLQFNGELYNKEI
SQGDNDSLYIASMLQNLKEGMGVIDVIKSLEGEYAYTIYDVNSSKLYFGRDPIGRRSL
SYSVTPDNELYVASVTGSAGSFQDCIGGVIYEYDTRTKLLNSNQRSHLPYEVTSEIDL
NFTSLSEVSKNLYAVLRDSVKKRVESIHPRHIENSPIAVLFSGGIDCSVIVALICEVL
QENDYKCGKPVIELLNVSFENPRTGLFPSDTPDRKLSINSAKTLQNLYPNVDIKLVEV
DVPYDEYLKWKPFVINLMYPKQTEMDLSIAIAFFFASRGRGFLTSLNGERTPYQRHGI
VLFSGLGADELYGGYHKFANKPPHELVEELTRQINNIYDRNLNRDDKVIAHNGVEVRY
PFLDEYVIKLSTAEIPINFKVNKLILRKVASQYLKLDGISSEPKRAIQFGAKSAKMTK
DGNKHGTDLLKENRNCS"
gene complement(81481..82113)
/gene="RAD10"
/locus_tag="YML095C"
/db_xref="GeneID:854878"
mRNA complement(81481..82113)
/gene="RAD10"
/locus_tag="YML095C"
/product="Rad10p"
/transcript_id="NM_001182454.1"
/db_xref="GI:296147024"
/db_xref="GeneID:854878"
CDS complement(81481..82113)
/gene="RAD10"
/locus_tag="YML095C"
/note="Single-stranded DNA endonuclease (with Rad1p),
cleaves single-stranded DNA during nucleotide excision
repair and double-strand break repair; subunit of
Nucleotide Excision Repair Factor 1 (NEF1); homolog of
human ERCC1 protein"
/codon_start=1
/product="Rad10p"
/protein_id="NP_013614.1"
/db_xref="GI:6323543"
/db_xref="SGD:S000004560"
/db_xref="GeneID:854878"
/translation="MNNTDPTSFESILAGVAKLRKEKSGADTTGSQSLEIDASKLQQQ
EPQTSRRINSNQVINAFNQQKPEEWTDSKATDDYNRKRPFRSTRPGKTVLVNTTQKEN
PLLNHLKSTNWRYVSSTGINMIYYDYLVRGRSVLFLTLTYHKLYVDYISRRMQPLSRN
ENNILIFIVDDNNSEDTLNDITKLCMFNGFTLLLAFNFEQAAKYIEYLNL"
gene 82275..82849
/gene="GIM5"
/locus_tag="YML094W"
/gene_synonym="PFD5"
/db_xref="GeneID:854879"
mRNA join(82275..82290,82374..82849)
/gene="GIM5"
/locus_tag="YML094W"
/gene_synonym="PFD5"
/product="Gim5p"
/transcript_id="NM_001182453.1"
/db_xref="GI:296147025"
/db_xref="GeneID:854879"
CDS join(82275..82290,82374..82849)
/gene="GIM5"
/locus_tag="YML094W"
/gene_synonym="PFD5"
/note="Subunit of the heterohexameric cochaperone
prefoldin complex which binds specifically to cytosolic
chaperonin and transfers target proteins to it"
/codon_start=1
/product="Gim5p"
/protein_id="NP_013616.1"
/db_xref="GI:6323544"
/db_xref="SGD:S000004559"
/db_xref="GeneID:854879"
/translation="MSSQKIDLTKLNPEQLNAVKQQFDQELQHFTQSLQALTMAKGKF
TECIDDIKTVSQAGNEGQKLLVPASASLYIPGKIVDNKKFMVDIGTGYYVEKSAEAAI
AFYQKKVDKLNKESVQIQDIIKEKTQYSLSIEAQIRQAAIRQHEAMSKQQQQQQKKES
STA"
gene 83090..85789
/gene="UTP14"
/locus_tag="YML093W"
/db_xref="GeneID:854881"
mRNA 83090..85789
/gene="UTP14"
/locus_tag="YML093W"
/product="Utp14p"
/transcript_id="NM_001182452.1"
/db_xref="GI:296147026"
/db_xref="GeneID:854881"
CDS 83090..85789
/gene="UTP14"
/locus_tag="YML093W"
/note="Subunit of U3-containing Small Subunit (SSU)
processome complex involved in production of 18S rRNA and
assembly of small ribosomal subunit"
/codon_start=1
/product="Utp14p"
/protein_id="NP_013617.1"
/db_xref="GI:6323546"
/db_xref="SGD:S000004558"
/db_xref="GeneID:854881"
/translation="MAKKKSKSRSKSSRRVLDALQLAEREINGEFDNSSDNDKRHDAR
RNGTVVNLLKRSKGDTNSDEDDIDSESFEDEELNSDEALGSDDDYDILNSKFSQTIRD
KKENANYQEEEDEGGYTSIDEEDLMPLSQVWDMDEKTAQSNGNDDEDASPQLKLQDTD
ISSESSSSEESESESEDDEEEEDPFDEISEDEEDIELNTITSKLIDETKSKAPKRLDT
YGSGEANEYVLPSANAASGASGKLSLTDMMNVIDDRQVIENANLLKGKSSTYEVPLPQ
RIQQRHDRKAAYEISRQEVSKWNDIVQQNRRADHLIFPLNKPTEHNHASAFTRTQDVP
QTELQEKVDQVLQESNLANPEKDSKFEELSTAKMTPEEMRKRTTEMRLMRELMFREER
KARRLKKIKSKTYRKIKKKELMKNRELAAVSSDEDNEDHDIARAKERMTLKHKTNSKW
AKDMIKHGMTNDAETREEMEEMLRQGERLKAKMLDRNSDDEEDGRVQTLSDVENEEKE
NIDSEALKSKLGKTGVMNMAFMKNGEAREREANKETLRQLRAVENGDDIKLFESDEEE
TNGENIQINKGRRIYTPGSLESNKDMNELNDHTRKENKVDESRSLENRLRAKNSGQSK
NARTNAEGAIIVEEESDGEPLQDGQNNQQDEEAKDVNPWLANESDEEHTVKKQSSKVN
VIDKDSSKNVKAMNKMEKAELKQKKKKKGKSNDDEDLLLTADDSTRLKIVDPYGGSDD
EQGDNVFMFKQQDVIAEAFAGDDVVAEFQEEKKRVIDDEDDKEVDTTLPGWGEWAGAG
SKPKNKKRKFIKKVKGVVNKDKRRDKNLQNVIINEKVNKKNLKYQSSAVPFPFENREQ
YERSLRMPIGQEWTSRASHQELIKPRIMTKPGQVIDPLKAPFK"
gene complement(85987..86739)
/gene="PRE8"
/locus_tag="YML092C"
/db_xref="GeneID:854882"
mRNA complement(85987..86739)
/gene="PRE8"
/locus_tag="YML092C"
/product="proteasome core particle subunit alpha 2"
/transcript_id="NM_001182451.1"
/db_xref="GI:296147027"
/db_xref="GeneID:854882"
CDS complement(85987..86739)
/gene="PRE8"
/locus_tag="YML092C"
/EC_number="3.4.25.1"
/note="Alpha 2 subunit of the 20S proteasome"
/codon_start=1
/product="proteasome core particle subunit alpha 2"
/protein_id="NP_013618.1"
/db_xref="GI:6323547"
/db_xref="SGD:S000004557"
/db_xref="GeneID:854882"
/translation="MTDRYSFSLTTFSPSGKLGQIDYALTAVKQGVTSLGIKATNGVV
IATEKKSSSPLAMSETLSKVSLLTPDIGAVYSGMGPDYRVLVDKSRKVAHTSYKRIYG
EYPPTKLLVSEVAKIMQEATQSGGVRPFGVSLLIAGHDEFNGFSLYQVDPSGSYFPWK
ATAIGKGSVAAKTFLEKRWNDELELEDAIHIALLTLKESVEGEFNGDTIELAIIGDEN
PDLLGYTGIPTDKGPRFRKLTSQEINDRLEAL"
gene complement(87123..90731)
/gene="RPM2"
/locus_tag="YML091C"
/db_xref="GeneID:854883"
mRNA complement(87123..90731)
/gene="RPM2"
/locus_tag="YML091C"
/product="Rpm2p"
/transcript_id="NM_001182450.1"
/db_xref="GI:296147028"
/db_xref="GeneID:854883"
CDS complement(87123..90731)
/gene="RPM2"
/locus_tag="YML091C"
/EC_number="3.1.26.5"
/note="Protein subunit of mitochondrial RNase P, has roles
in nuclear transcription, cytoplasmic and mitochondrial
RNA processing, and mitochondrial translation; distributed
to mitochondria, cytoplasmic processing bodies, and the
nucleus"
/codon_start=1
/product="Rpm2p"
/protein_id="NP_013619.1"
/db_xref="GI:6323548"
/db_xref="SGD:S000004556"
/db_xref="GeneID:854883"
/translation="MAFKSFIYSKGYHRSAAQKKTATSFFDSSYQYLRQNQGLVNSDP
VLHASHLHPHPVVVANVNYNNVDDILHPHDLDSSINNTNNPLTHEELLYNQNVSLRSL
KQQQSTNYVNNNNNNQHRYYSTGPTLPTNQYDPLNFSNRNFQDLSLKTSQPSVQQPQN
EYSLLKDENAPVWKEDTEPCLNKSTYLQTHIDEINRCYEQKNYNKINSLYQSLKRNDI
VPPLEIFTKVLDSLCKRPLDNNDLDNKMYELLTCYQDMINNRLKPPDEIYNIVLLSLF
KGSILAYQFENPNGSDFYKIAIELFNTTTNDPKQKSVVKFRNFSKDVLDYNLLAMNIY
PGHITLSKAQQVIKSSPAFIKDSFYFIACFSYAKLTNDKFAIKELYEDFRLSLSSGSP
DQGLFDDQFEIYSVILSSFIETGEVELATNLLDDLVSKIQSSNGLASNISLLLSSFLI
SMSKVDPSKAYEIWFKFHNLNWIPEFSYEFYLVFMANSFQDWNLTKKIYDYIFPMERN
LSPLKKQKLSDYLLHPIGVDSITTSLLDYSLQLKDNEVIMKILEESIVKNFSFDIGIY
PFVFNYLREIQCGEDYLMRFIESHAEFIKKSNSINKFQFLNMIVDNFQSQSLLNKISH
AKFFKNFVEDFNLENCELVSYNGLISCINNFIKIPKTIKDFPYILEIHAILVTKLFDF
DTYPILQNGNNEVLLKFRDQIEHQFKMLAQNFCRLNLDPNLLAGVVSQAMKMVNLDDT
ANGQDLLNFFNHPGDWDKSYPLSLGSFIRNSPRGGIREFTKLSKEGYCFDYDTYKELI
IKRAINKQIIDKCLEVCPDSIELKNIVNLMISKIPGRNLTQLIINNPKFSKVFVPNLR
NDSMLKLIENCESLSNFIRICDFPEKFKSIAIQAENKNAIELIYERLFDGGKYADILR
YNNIVPVLNLELLLKSCIRSGEFKKYESLSKKFNDKISESSKIDIQLEYLINKNDLKG
AFTLFEKTPRELRTPHKTMDLYTFALFLDSFNRNITYYESPENTLQFANILSSQTSFI
NLLSTYNLIAHSDHLMNFNVGGMAAKVKKEILNQMLNNLYDSIRLLSPSIENDKSMKE
KLREKVKNYCRFKAYLKSPELDMDELKTLVSVESFLNPFTPSMLFNNLIETIYINEHA
SSLVLQNGLIYSLQQKGLNKILSYLEESFITSGNDANIEKVREFRSLLRKSKPLQA"
gene 92235..94241
/gene="UFO1"
/locus_tag="YML088W"
/db_xref="GeneID:854886"
mRNA 92235..94241
/gene="UFO1"
/locus_tag="YML088W"
/product="SCF ubiquitin ligase complex subunit UFO1"
/transcript_id="NM_001182447.1"
/db_xref="GI:296147029"
/db_xref="GeneID:854886"
CDS 92235..94241
/gene="UFO1"
/locus_tag="YML088W"
/note="F-box receptor protein, subunit of the
Skp1-Cdc53-F-box receptor (SCF) E3 ubiquitin ligase
complex; binds to phosphorylated Ho endonuclease, allowing
its ubiquitylation by SCF and subsequent degradation"
/codon_start=1
/product="SCF ubiquitin ligase complex subunit UFO1"
/protein_id="NP_013622.1"
/db_xref="GI:6323551"
/db_xref="SGD:S000004553"
/db_xref="GeneID:854886"
/translation="MERPGLVLQDLPPEILINIFSHLDEKDLFTLQELSTHFRNLIHD
EELWKNLFKSRVHTTHFPTFSQSSKFSVEYIERTRGLHHWQHNKAIRTKYTIIPTRNW
DQPSIERIVFDYPRVAAYNDGTITILQLQNHKRQKKFKKLIYIPCTTPQGCSTMDFNI
NAAVFGRFDGRVFGKLLSNKSYLTPVMEFTGRHSAGVTAICNSESWDTSREDWSVSGS
ENGEIIWWCENKLVKMWKVSNRVIWKLAFFKDWTLIMDDEKLYIIHQMQELHSIDIPK
DLDEQPMRVRFFKMDFGSMTLVLADLNNVYTISVNPNGNFGNLRKLEMPEQICAVEID
EKTSQREQNWQFAGDDGCYISLLTTQNTLYIINIRDLSSSGLKVQCKISFDEQVYVSQ
VTNLIVVVALPNVLQILNAMTGELIKTVLKTEKFPEFLKVSQDKIIMGSGNVLNYLKF
VSSDSKKHHHSTKGKNTVSNKWNETLNTELQYYDEDEDLRRKRQSEISRLIDAYGGDL
ELSGDTDEENDIQLRIALLESQEAQARNQAEAGEPVGDDEDEQLRRALEESQLIYETQ
TNSSANHGNNTNDEIDEDDEEFLRAIRQSRVEDERRRHLRNHTTGRRNGPLSDDNFAT
YGAAESSERTSTENTIGSSVGVDASNNVDEDLQLAIALSLSEIN"
rep_origin 94217..94463
/note="ARS1305;
Autonomously Replicating Sequence"
/db_xref="SGD:S000118366"
gene complement(94431..95369)
/gene="AIM33"
/locus_tag="YML087C"
/db_xref="GeneID:854887"
mRNA complement(94431..95369)
/gene="AIM33"
/locus_tag="YML087C"
/product="Aim33p"
/transcript_id="NM_001182446.1"
/db_xref="GI:296147030"
/db_xref="GeneID:854887"
CDS complement(94431..95369)
/gene="AIM33"
/locus_tag="YML087C"
/EC_number="1.-.-.-"
/note="hypothetical protein, highly conserved across
species and orthologous to human CYB5R4; null mutant
displays reduced frequency of mitochondrial genome loss"
/codon_start=1
/product="Aim33p"
/protein_id="NP_013623.1"
/db_xref="GI:6323552"
/db_xref="SGD:S000004552"
/db_xref="GeneID:854887"
/translation="MSIVETCISFVSTNPFYPFCTGLLLNCVVTPLYFWKTQNGRIVV
VSLLQFVVLYATAFISIGTDKSLYRNKWVALPLSKKTRISRNTSLYCFKLKYPFERLH
IPMGYHLAVRVTINGERLVRYYTPVNVPNTEGHLELVVKTYKHGVVSKYFDKLKIRQY
VEFKGPLGELEYDQDTATELGIIAGGSGITPVLQVLQEIIPSPEDLTHISLIYANETE
DDILMKSQLDHMAKEYPHFKVHYVIHKPNGKWNGDVGYVTLEEMKRYLPKQAEDHRLL
ICGPPKMNEMVLNYAKELGWSNGFHKGNGTDKVFVF"
gene complement(95791..97371)
/gene="ALO1"
/locus_tag="YML086C"
/db_xref="GeneID:854888"
mRNA complement(95791..97371)
/gene="ALO1"
/locus_tag="YML086C"
/product="D-arabinono-1,4-lactone oxidase"
/transcript_id="NM_001182445.1"
/db_xref="GI:296147031"
/db_xref="GeneID:854888"
CDS complement(95791..97371)
/gene="ALO1"
/locus_tag="YML086C"
/EC_number="1.1.3.37"
/note="D-Arabinono-1,4-lactone oxidase, catalyzes the
final step in biosynthesis of
dehydro-D-arabinono-1,4-lactone, which is protective
against oxidative stress"
/codon_start=1
/product="D-arabinono-1,4-lactone oxidase"
/protein_id="NP_013624.1"
/db_xref="GI:6323553"
/db_xref="SGD:S000004551"
/db_xref="GeneID:854888"
/translation="MSTIPFRKNYVFKNWAGIYSAKPERYFQPSSIDEVVELVKSARL
AEKSLVTVGSGHSPSNMCVTDEWLVNLDRLDKVQKFVEYPELHYADVTVDAGMRLYQL
NEFLGAKGYSIQNLGSISEQSVAGIISTGSHGSSPYHGLISSQYVNLTIVNGKGELKF
LDAENDPEVFKAALLSVGKIGIIVSATIRVVPGFNIKSTQEVITFENLLKQWDTLWTS
SEFIRVWWYPYTRKCVLWRGNKTTDAQNGPAKSWWGTKLGRFFYETLLWISTKIYAPL
TPFVEKFVFNRQYGKLEKSSTGDVNVTDSISGFNMDCLFSQFVDEWGCPMDNGLEVLR
SLDHSIAQAAINKEFYVHVPMEVRCSNTTLPSEPLDTSKRTNTSPGPVYGNVCRPFLD
NTPSHCRFAPLENVTNSQLTLYINATIYRPFGCNTPIHKWFTLFENTMMVAGGKPHWA
KNFLGSTTLAAGPVKKDTDYDDFEMRGMALKVEEWYGEDLKKFRKIRKEQDPDNVFLA
NKQWAIINGIIDPSELSD"
gene complement(97941..99400)
/gene="TUB1"
/locus_tag="YML085C"
/db_xref="GeneID:854889"
mRNA complement(join(97941..99259,99376..99400))
/gene="TUB1"
/locus_tag="YML085C"
/product="Tub1p"
/transcript_id="NM_001182444.1"
/db_xref="GI:296147032"
/db_xref="GeneID:854889"
CDS complement(join(97941..99259,99376..99400))
/gene="TUB1"
/locus_tag="YML085C"
/note="Alpha-tubulin; associates with beta-tubulin (Tub2p)
to form tubulin dimer, which polymerizes to form
microtubules; relative distribution to nuclear foci
increases upon DNA replication stress"
/codon_start=1
/product="Tub1p"
/protein_id="NP_013625.1"
/db_xref="GI:6323554"
/db_xref="SGD:S000004550"
/db_xref="GeneID:854889"
/translation="MREVISINVGQAGCQIGNACWELYSLEHGIKPDGHLEDGLSKPK
GGEEGFSTFFHETGYGKFVPRAIYVDLEPNVIDEVRNGPYKDLFHPEQLISGKEDAAN
NYARGHYTVGREILGDVLDRIRKLADQCDGLQGFLFTHSLGGGTGSGLGSLLLEELSA
EYGKKSKLEFAVYPAPQVSTSVVEPYNTVLTTHTTLEHADCTFMVDNEAIYDMCKRNL
DIPRPSFANLNNLIAQVVSSVTASLRFDGSLNVDLNEFQTNLVPYPRIHFPLVSYSPV
LSKSKAFHESNSVSEITNACFEPGNQMVKCDPRDGKYMATCLLYRGDVVTRDVQRAVE
QVKNKKTVQLVDWCPTGFKIGICYEPPTATPNSQLATVDRAVCMLSNTTSIAEAWKRI
DRKFDLMYAKRAFVHWYVGEGMEEGEFTEAREDLAALERDYIEVGADSYAEEEEF"
gene complement(99794..101050)
/locus_tag="YML083C"
/db_xref="GeneID:854891"
mRNA complement(99794..101050)
/locus_tag="YML083C"
/product="hypothetical protein"
/transcript_id="NM_001182442.1"
/db_xref="GI:296147033"
/db_xref="GeneID:854891"
CDS complement(99794..101050)
/locus_tag="YML083C"
/note="hypothetical protein; transcriptionally regulated
by Upc2p via an upstream sterol response element; strong
increase in transcript abundance during anaerobic growth
compared to aerobic growth; cells deleted for YML083C do
not exhibit growth defects in anerobic or anaerobic
conditions"
/codon_start=1
/product="hypothetical protein"
/protein_id="NP_013627.1"
/db_xref="GI:6323556"
/db_xref="SGD:S000004548"
/db_xref="GeneID:854891"
/translation="MDYLHVYNNNQAHVPRTPPGRQCLSPVLPPIILALDQQHSLTFG
YSSPRCLPTPILPSMSTNTPVHWSQQVVTIPVAVRNHAAMMPIITPMTSPRPQFEATA
PSPPLAPVAIKLPDLKLPPSPVPSTVEDRVSHPILPKIVIGNGGGRDVERDSTEELIR
KIPNYIGCAKTKAQLSKVRSGKQLIACAQEYHHPVNKDEIENINNILNFRDFIFKHPK
SSFEFLCTLSFEQFVRVYSFISFIYRTKKINKNKYELVCEMNVHEQLSNKRIQRTRTP
EKYKIHLICESKLILTFNHCTKTVKFESINGGHCHPISANHIIKPSLFLTHCINKCYQ
TVSDPTDLKLALRDALEALDHERIGLSFLKRRHFKCSHQASSLSNASATLKKQEDHDT
FGVHTGIIHTANFFMFNASSDIFQRN"
gene 101862..103811
/locus_tag="YML082W"
/db_xref="GeneID:854892"
mRNA 101862..103811
/locus_tag="YML082W"
/product="putative cystathionine gamma-synthase"
/transcript_id="NM_001182441.1"
/db_xref="GI:296147034"
/db_xref="GeneID:854892"
CDS 101862..103811
/locus_tag="YML082W"
/EC_number="2.5.1.48"
/note="Putative protein predicted to have carbon-sulfur
lyase activity; transcriptionally regulated by Upc2p via
an upstream sterol response element; green fluorescent
protein (GFP)-fusion protein localizes to the nucleus and
the cytoplasm; YML082W is not an essential gene"
/codon_start=1
/product="putative cystathionine gamma-synthase"
/protein_id="NP_013628.1"
/db_xref="GI:6323557"
/db_xref="SGD:S000004547"
/db_xref="GeneID:854892"
/translation="MVSAQVATELGQPIPLDTQHAVSVCFPTWKSVISYVEKDPKVLG
CLKSGYPRFWIHPSIQKLRDILIEKYAKENETCFCFPSYRVAKRCREYVRRKCAHRNG
KVRILQLATAKPINEEQKTWKRECKIAVVFVDGAYENILKQYWQYTGEIISSRLAEYV
LHELFMVEKKSSPAEEKEYIEMRYGRNLNFAFADRAKELIKKRIATKVIDKDEHDEEE
NYHFLAGNQDEQDFQDTFLDSSLNEANHGEDHDGGISGEVDSQEEPHNGLVSTIPPEP
IEMSTIEEEQSVEEDAGRCALRVCPERDVFLFPSGMASIFTAHRLLLQWDSLRLNRSR
NGSDVTSSPPNKKTVIFGFPYADTLHVLQEFNETYFLGEGDESSMKELTKILHSGEQI
LAVFIETPSNPLLKMGNLLELKRLSELFGFFIIIDETVGGIVNIDGLPFADIVCSSLT
KTFSGDSNVIGGSMVLNPQSRVYEFASRFMQLEDEYEDLLWCEDAIYLERNSRDFIAR
TIRINYSTEYLLDKILKPHVGENKLFKKIYYPNLTSKETLTNYDMVRCKKEGGYGGLF
SLTFHDEDHAAAFYDNLKLNKGPSLGTNFTLAFPYTLMTYYHELDMAEKFGVERNLLR
ISVGLESQSILGKIFQEAIDKTVEI"
gene complement(103983..104162)
/gene="ATP18"
/locus_tag="YML081C-A"
/db_xref="GeneID:854893"
mRNA complement(103983..104162)
/gene="ATP18"
/locus_tag="YML081C-A"
/product="Atp18p"
/transcript_id="NM_001184340.1"
/db_xref="GI:296147035"
/db_xref="GeneID:854893"
CDS complement(103983..104162)
/gene="ATP18"
/locus_tag="YML081C-A"
/EC_number="3.6.3.14"
/note="Subunit of the mitochondrial F1F0 ATP synthase,
which is a large enzyme complex required for ATP
synthesis; termed subunit I or subunit j; does not
correspond to known ATP synthase subunits in other
organisms"
/codon_start=1
/product="Atp18p"
/protein_id="NP_013629.1"
/db_xref="GI:6323558"
/db_xref="SGD:S000007247"
/db_xref="GeneID:854893"
/translation="MLKRFPTPILKVYWPFFVAGAAVYYGMSKAADLSSNTKEFINDP
RNPRFAKGGKFVEVD"
gene 104777..108532
/gene="TDA9"
/locus_tag="YML081W"
/db_xref="GeneID:854894"
mRNA 104777..108532
/gene="TDA9"
/locus_tag="YML081W"
/product="Tda9p"
/transcript_id="NM_001182440.1"
/db_xref="GI:296147036"
/db_xref="GeneID:854894"
CDS 104777..108532
/gene="TDA9"
/locus_tag="YML081W"
/note="DNA-binding protein, putative transcription factor;
green fluorescent protein (GFP)-fusion protein localizes
to the nucleus; null mutant is sensitive to expression of
the top1-T722A allele; not an essential gene; TDA9 has a
paralog, RSF2, that arose from the whole genome
duplication"
/codon_start=1
/product="Tda9p"
/protein_id="NP_013630.1"
/db_xref="GI:6323559"
/db_xref="SGD:S000004546"
/db_xref="GeneID:854894"
/translation="MSSEEFKGLPIKRDISSTIYADRPPALSAPPCVGATGNDKIQVL
PIPKKSRTIKTDKPRPFLCHICTRGFVRQEHLKRHQRAHTNEKPFLCVFCGRCFARRD
LVLRHQHKLHSALVSKESINSKDKTEIDAINDKNIIQIQGNKQTILPTPSNPLAKTAV
QLKKAAKEKKNGKQGKLDLSPSYGANNHSTDVSPSVGNSSTPAVIEETDSSSHFPLPD
TNIPTKSKRHASFSASSAFTYSSDNFQKLHQQAKSDFDELQESIPHQVGFSTPQLTAQ
QLIENAIESGVVDLETLDLPPFLSLDGLPPASSSAAVAASEQIDICPSSATDTISGAN
STPNQAATAPPFQLPIARESSSLFLANTPYLSDFLTMGSSYGGSGGFAKSITADPSLD
YFNYKNHSHPDSRHNNSSSGINYSNNKNNNESIEKSQNNSNVINETIDHTDIHAHHAD
AHDDSFIESEEWLSKFIMDSQIDNDLKLNINHFNDIGFNNLHPQNPTTHSEPRNMHNE
NRDMHRSASKFQSVSENISPREQMSLFKTKQNKAISKFLSDEKIPSTASPSSSASPVQ
FDKKNVDINEFLLDESVSNLFTTRQIDLFKKNVNLYSPLFQNQKDAVSSTSLTPSLTT
QTATTQSGPGWTDSSQKLTFFTEQLRNLIIKENNLKSNLFPTVDELNHYVDLYQVEFH
KYFPFIHLYSIIPSSENYPLVISISMIGALYGFHSTHALLLSKIARTRVRMFLENTRS
NHDKTPIWLMQSLVLLTFTSIFSNDMNAFRTVNTQIMILVQLIKISKLNYPLENFIKP
PIESDHVLEYQDNPAVLNQFKAQYNTREQINRNFKYFILAQSRIRICHIVLLISNLFK
SLVDFDCCFHSIDLKCGVPCYNEVLFFCENSRTWNENLTRFNIVLDSKFSLIEVSNGE
SNYEKCLMYLSNGNPYLYKNAKISFKTLLSLLISIHEKINIERDALKDSYESDFHAKN
VQWRMHSRPLVATMLKHWELLYIKNGGILALSDENLPIINTNPSFRLIIPLYFFAKLR
KCLDIAPTLRCIWNQDWNSMNSSLEKVCYERESLREATEYAVSVITFWIDTVSVMKGK
STQTPIFTITCIFVSILVIAGYMRRLEDFAQNKNSDCMIGSLKSTDRILWLKAFKTLK
RIESHLSEREYKLQTFAEFLRVPDNGSLDIESLDSSLIENTLNSHDVTNQALDIITRT
RLSSRTLYCGARILGDTPVWPVSLLFAHALQSRAIYNINHRKSVNSV"
gene 108806..110077
/gene="DUS1"
/locus_tag="YML080W"
/db_xref="GeneID:854895"
mRNA 108806..110077
/gene="DUS1"
/locus_tag="YML080W"
/product="Dus1p"
/transcript_id="NM_001182439.1"
/db_xref="GI:296147037"
/db_xref="GeneID:854895"
CDS 108806..110077
/gene="DUS1"
/locus_tag="YML080W"
/EC_number="1.-.-.-"
/note="Dihydrouridine synthase, member of a widespread
family of conserved proteins including Smm1p, Dus3p, and
Dus4p; modifies pre-tRNA(Phe) at U17"
/codon_start=1
/product="Dus1p"
/protein_id="NP_013631.1"
/db_xref="GI:6323560"
/db_xref="SGD:S000004545"
/db_xref="GeneID:854895"
/translation="MTEPALSSANNALMQKLTGRQLFDKIGRPTRIVAPMVDQSELAW
RILSRRYGATLAYTPMLHAKLFATSKKYREDNWSSLDGSSVDRPLVVQFCANDPEYLL
AAAKLVEDKCDAVDLNLGCPQGIAKKGHYGSFLMEEWDLIHNLINTLHKNLKVPVTAK
IRIFDDCEKSLNYAKMVLDAGAQFLTVHGRVREQKGQKTGLANWETIKYLRDNLPKET
VFFANGNILYPEDISRCMEHIGADAVMSAEGNLYNPGVFNVGQTKNKEKIFPRVDKII
REYFQIVKECQESKASKTAMKSHFFKILRPFLPHHTDIRSTLATMNAKATWEEWEEQV
VKPVEKVVQEIFEQPDIAIKDEITIGEKQSWGGSYRTVPYWRCQPYFRPVNGITGDKR
VMQGLIDESVNKKRKADVPLESADKKKDVKA"
gene 110247..110852
/locus_tag="YML079W"
/db_xref="GeneID:854896"
mRNA 110247..110852
/locus_tag="YML079W"
/product="hypothetical protein"
/transcript_id="NM_001182438.1"
/db_xref="GI:296147038"
/db_xref="GeneID:854896"
CDS 110247..110852
/locus_tag="YML079W"
/note="Non-essential hypothetical protein with structural
resemblance to plant storage and ligand binding proteins
(canavalin, glycinin, auxin binding protein) and to some
enzymes (epimerase, germin); localizes to the nucleus and
cytoplasm"
/codon_start=1
/product="hypothetical protein"
/protein_id="NP_013632.1"
/db_xref="GI:6323561"
/db_xref="SGD:S000004544"
/db_xref="GeneID:854896"
/translation="MSANVQEAANAAIEPASFVKVPMPEPPSSLQQLINDWQLIKHRE
GGYFKETDRSPYTMEVEKPVNGGSGNTEMVTRNQSTLIYYLLTPDSPIGKFHKNINRI
IHILQRGKGQYVLVYPDGQVKSFKVGFDYKNGEVSQWVVPGGVFKASFLLPNEEFDNG
FLISEVVVPGFDFEDHTFLKGEDELKHLVGPEKAAELAFLA"
gene 111002..111550
/gene="CPR3"
/locus_tag="YML078W"
/gene_synonym="CYP3"
/db_xref="GeneID:854897"
mRNA 111002..111550
/gene="CPR3"
/locus_tag="YML078W"
/gene_synonym="CYP3"
/product="peptidylprolyl isomerase CPR3"
/transcript_id="NM_001182437.1"
/db_xref="GI:296147039"
/db_xref="GeneID:854897"
CDS 111002..111550
/gene="CPR3"
/locus_tag="YML078W"
/gene_synonym="CYP3"
/EC_number="5.2.1.8"
/note="Mitochondrial peptidyl-prolyl cis-trans isomerase
(cyclophilin), catalyzes the cis-trans isomerization of
peptide bonds N-terminal to proline residues; involved in
protein refolding after import into mitochondria"
/codon_start=1
/product="peptidylprolyl isomerase CPR3"
/protein_id="NP_013633.1"
/db_xref="GI:6323562"
/db_xref="SGD:S000004543"
/db_xref="GeneID:854897"
/translation="MFKRSIIQQSRLFSNSASRLGKKVFFDPAVNGTKIGRIEFELYD
NVVPKTAENFRALCTGEKGWGYKGVPFHRIIPDFMIQGGDTDLTNGFGGKSIYGSKFA
DENFVKKHDKAGLLSMANAGPNTNGSQFFITTVPCPWLDGKHVVFGEVTKGMDIVKAI
ESYGTASGKPRAEIVIEEAGEL"
gene 111865..112344
/gene="BET5"
/locus_tag="YML077W"
/db_xref="GeneID:854898"
mRNA 111865..112344
/gene="BET5"
/locus_tag="YML077W"
/product="Bet5p"
/transcript_id="NM_001182436.1"
/db_xref="GI:296147040"
/db_xref="GeneID:854898"
CDS 111865..112344
/gene="BET5"
/locus_tag="YML077W"
/note="Component of the TRAPP (transport protein particle)
complex, which plays an essential role in the vesicular
transport from endoplasmic reticulum to Golgi"
/codon_start=1
/product="Bet5p"
/protein_id="NP_013634.1"
/db_xref="GI:6323563"
/db_xref="SGD:S000004542"
/db_xref="GeneID:854898"
/translation="MGIYSFWIFDRHCNCIFDREWTLASNSASGTINSKQNEEDAKLL
YGMIFSLRSITQKLSKGSVKNDIRSISTGKYRVHTYCTASGLWFVLLSDFKQQSYTQV
LQYIYSHIYVKYVSNNLLSPYDFAENENEMRGQGTRKITNRNFISVLESFLAPMVNQ"
gene complement(112513..115347)
/gene="WAR1"
/locus_tag="YML076C"
/db_xref="GeneID:854899"
mRNA complement(112513..115347)
/gene="WAR1"
/locus_tag="YML076C"
/product="War1p"
/transcript_id="NM_001182435.1"
/db_xref="GI:296147041"
/db_xref="GeneID:854899"
CDS complement(112513..115347)
/gene="WAR1"
/locus_tag="YML076C"
/note="Homodimeric Zn2Cys6 zinc finger transcription
factor; binds to a weak acid response element to induce
transcription of PDR12 and FUN34, encoding an acid
transporter and a putative ammonia transporter,
respectively"
/codon_start=1
/product="War1p"
/protein_id="NP_013635.1"
/db_xref="GI:6323564"
/db_xref="SGD:S000004541"
/db_xref="GeneID:854899"
/translation="MDTQIAITGVAVGKEINNDNSKTDQKVSLPKADVPCIDKATQTI
IEGCSKDDPRLSYPTKLETTEKGKTKRNSFACVCCHSLKQKCEPSDVNDIYRKPCRRC
LKHKKLCKFDLSKRTRKRKPRSRSPTPFESPMVNVSTKSKGPTDSEESSLKDGTSYLA
SFPSDPNAKQFPNSRTVLPGLQQSLSDLWSTLSQPPSYGAREAETTSTGEITTNNHTK
SNGSVPTNPAVLASNDEHTNISDAPVIYSTYNSPVPISSAPTSINSEALFKHRPKIVG
DEETQNVKVKRQKKSYSRHMTRSFRKQLQSLIISQKGKIRDISMKLDTWSKQWNDLVE
KSMFLPTIADPVSVGIISHEEATLRLHLYKTEISYLSKLPFIKVEENVSVDELRKKKP
ILFSVIMSCVSIVLTPKQTTRGTIMKLDSFVLNLITNQIFKANNKSIEIIESLSTLCL
WYNFFEWSSKTRYHIFNYICCCLTRDLGPTYVNRSFGMFSDEDPKRFKSPLELYSNGA
SLTLLVYISALNISIFLRQSIQARWSHVTEKACEDLVKETKKSRHYDNDKLLLDSADD
PILVQFAKMNHVLENIHTHLHERDLNDDEFDDPIFTKKYLNKLMEKYHKQLQEIFTKL
DRNRPRVIAFYYSVEAYLYQYKLAVFIGEMSHTINEKVELPREIMDDFVKCYHCCKSA
LEEFSKLEPILITSLPLFHTSRIIYTVGMLLLKLRYSVVAIPSFHDLMPLTDDAIALV
IGVNNLLEKTSELYPFNNSLYKFRYVIALFCQTYANKVIDVADRYNAEREKLKEKQVI
DEVSNGHDGTKPINAYVTESQKMPTEEDPIIDNNTNQNITAVPDEMLPVYSRVRDDTA
AMNLNINSTSYMNESPHEHRESMTGTTLLPPPFISNDVTNSADSTNIKPSPSSSVDNL
NDYLTDINSLAWGVNSLNDEFWTDLFMNDI"
gene complement(115734..118898)
/gene="HMG1"
/locus_tag="YML075C"
/db_xref="GeneID:854900"
mRNA complement(115734..118898)
/gene="HMG1"
/locus_tag="YML075C"
/product="hydroxymethylglutaryl-CoA reductase (NADPH)
HMG1"
/transcript_id="NM_001182434.1"
/db_xref="GI:296147042"
/db_xref="GeneID:854900"
CDS complement(115734..118898)
/gene="HMG1"
/locus_tag="YML075C"
/EC_number="1.1.1.34"
/note="HMG-CoA reductase; catalyzes the conversion of
HMG-CoA to mevalonate, which is a rate-limiting step in
sterol biosynthesis; one of two isozymes; localizes to the
nuclear envelope; overproduction induces the formation of
karmellae; forms foci at the nuclear periphery upon DNA
replication stress"
/codon_start=1
/product="hydroxymethylglutaryl-CoA reductase (NADPH)
HMG1"
/protein_id="NP_013636.1"
/db_xref="GI:6323565"
/db_xref="SGD:S000004540"
/db_xref="GeneID:854900"
/translation="MPPLFKGLKQMAKPIAYVSRFSAKRPIHIILFSLIISAFAYLSV
IQYYFNGWQLDSNSVFETAPNKDSNTLFQECSHYYRDSSLDGWVSITAHEASELPAPH
HYYLLNLNFNSPNETDSIPELANTVFEKDNTKYILQEDLSVSKEISSTDGTKWRLRSD
RKSLFDVKTLAYSLYDVFSENVTQADPFDVLIMVTAYLMMFYTIFGLFNDMRKTGSNF
WLSASTVVNSASSLFLALYVTQCILGKEVSALTLFEGLPFIVVVVGFKHKIKIAQYAL
EKFERVGLSKRITTDEIVFESVSEEGGRLIQDHLLCIFAFIGCSMYAHQLKTLTNFCI
LSAFILIFELILTPTFYSAILALRLEMNVIHRSTIIKQTLEEDGVVPSTARIISKAEK
KSVSSFLNLSVVVIIMKLSVILLFVFINFYNFGANWVNDAFNSLYFDKERVSLPDFIT
SNASENFKEQAIVSVTPLLYYKPIKSYQRIEDMVLLLLRNVSVAIRDRFVSKLVLSAL
VCSAVINVYLLNAARIHTSYTADQLVKTEVTKKSFTAPVQKASTPVLTNKTVISGSKV
KSLSSAQSSSSGPSSSSEEDDSRDIESLDKKIRPLEELEALLSSGNTKQLKNKEVAAL
VIHGKLPLYALEKKLGDTTRAVAVRRKALSILAEAPVLASDRLPYKNYDYDRVFGACC
ENVIGYMPLPVGVIGPLVIDGTSYHIPMATTEGCLVASAMRGCKAINAGGGATTVLTK
DGMTRGPVVRFPTLKRSGACKIWLDSEEGQNAIKKAFNSTSRFARLQHIQTCLAGDLL
FMRFRTTTGDAMGMNMISKGVEYSLKQMVEEYGWEDMEVVSVSGNYCTDKKPAAINWI
EGRGKSVVAEATIPGDVVRKVLKSDVSALVELNIAKNLVGSAMAGSVGGFNAHAANLV
TAVFLALGQDPAQNVESSNCITLMKEVDGDLRISVSMPSIEVGTIGGGTVLEPQGAML
DLLGVRGPHATAPGTNARQLARIVACAVLAGELSLCAALAAGHLVQSHMTHNRKPAEP
TKPNNLDATDINRLKDGSVTCIKS"
gene complement(120089..121324)
/gene="FPR3"
/locus_tag="YML074C"
/gene_synonym="NPI46"
/db_xref="GeneID:854901"
mRNA complement(120089..121324)
/gene="FPR3"
/locus_tag="YML074C"
/gene_synonym="NPI46"
/product="peptidylprolyl isomerase FPR3"
/transcript_id="NM_001182433.1"
/db_xref="GI:296147043"
/db_xref="GeneID:854901"
CDS complement(120089..121324)
/gene="FPR3"
/locus_tag="YML074C"
/gene_synonym="NPI46"
/EC_number="5.2.1.8"
/note="Nucleolar peptidyl-prolyl cis-trans isomerase
(PPIase); FK506 binding protein; phosphorylated by casein
kinase II (Cka1p-Cka2p-Ckb1p-Ckb2p) and dephosphorylated
by Ptp1p"
/codon_start=1
/product="peptidylprolyl isomerase FPR3"
/protein_id="NP_013637.1"
/db_xref="GI:6323566"
/db_xref="SGD:S000004539"
/db_xref="GeneID:854901"
/translation="MSDLLPLATYSLNVEPYTPVPAIDVTMPITVRITMAALNPEAID
EENKPSTLRIIKRNPDFEDDDFLGGDFDEDEIDEESSEEEEEEKTQKKKKSKGKKAES
ESEDDEEDDDEDDEFQESVLLTLSPEAQYQQSLDLTITPEEEVQFIVTGSYAISLSGN
YVKHPFDTPMGVEGEDEDEDADIYDSEDYDLTPDEDEIIGDDMDDLDDEEEEEVRIEE
VQEEDEEDNDGEEEQEEEEEEEQKEEVKPEPKKSKKEKKRKHEEKEEEKKAKKVKKVE
FKKDLEEGPTKPKSKKEQDKHKPKSKVLEGGIVIEDRTIGDGPQAKRGARVGMRYIGK
LKNGKVFDKNTSGKPFAFKLGRGEVIKGWDIGVAGMSVGGERRIIIPAPYAYGKQALP
GIPANSELTFDVKLVSMKN"
gene complement(123227..124172)
/gene="RPL6A"
/locus_tag="YML073C"
/gene_synonym="YL16A"
/db_xref="GeneID:854902"
mRNA complement(join(123227..123742,124158..124172))
/gene="RPL6A"
/locus_tag="YML073C"
/gene_synonym="YL16A"
/product="ribosomal 60S subunit protein L6A"
/transcript_id="NM_001182432.1"
/db_xref="GI:296147044"
/db_xref="GeneID:854902"
CDS complement(join(123227..123742,124158..124172))
/gene="RPL6A"
/locus_tag="YML073C"
/gene_synonym="YL16A"
/note="Ribosomal 60S subunit protein L6A; N-terminally
acetylated; binds 5.8S rRNA; homologous to mammalian
ribosomal protein L6, no bacterial homolog; RPL6A has a
paralog, RPL6B, that arose from the whole genome
duplication"
/codon_start=1
/product="ribosomal 60S subunit protein L6A"
/protein_id="NP_013638.1"
/db_xref="GI:6323567"
/db_xref="SGD:S000004538"
/db_xref="GeneID:854902"
/translation="MSAQKAPKWYPSEDVAALKKTRKAARPQKLRASLVPGTVLILLA
GRFRGKRVVYLKHLEDNTLLISGPFKVNGVPLRRVNARYVIATSTKVSVEGVNVEKFN
VEYFAKEKLTKKEKKEANLFPEQQNKEIKAERVEDQKVVDKALIAEIKKTPLLKQYLS
ASFSLKNGDKPHMLKF"
gene complement(124730..129367)
/gene="TCB3"
/locus_tag="YML072C"
/db_xref="GeneID:854903"
mRNA complement(124730..129367)
/gene="TCB3"
/locus_tag="YML072C"
/product="Tcb3p"
/transcript_id="NM_001182431.1"
/db_xref="GI:296147045"
/db_xref="GeneID:854903"
CDS complement(124730..129367)
/gene="TCB3"
/locus_tag="YML072C"
/note="Lipid-binding ER protein, enriched at ER-plasma
membrane contact sites; localized to the bud via specific
mRNA transport; non-tagged protein detected in a
phosphorylated state in mitochondria; C-termini of Tcb1p,
Tcb2p and Tcb3p interact"
/codon_start=1
/product="Tcb3p"
/protein_id="NP_013639.1"
/db_xref="GI:6323568"
/db_xref="SGD:S000004537"
/db_xref="GeneID:854903"
/translation="MTGIKAQVHPPPDSTLFHEEEKKKVGGNLPQKVINQQERGSDHA
PSGHHQYHQLINHDANDTKTSNSVSDVSKGQKTADSNPEGKKQSSKDIFVASSAQKTN
QLPGPNPQGSIGAVPLEGLRPKEFRSAPSRKPNKFDTSITKPGVLDDLGKLDEKDIKE
KFHLDSDDKLFPWQNVGEFHASGKGSPNTKMSRVIKAYILENFYNDWYCNIATVLGTC
FFSWLFAYIGFSWWSMIFIFLGTATVYNAEYTRFNRNIRDDLKRVTVEETLSDRVEST
TWLNSFLSKFWVIYMPVLSQQVKDNVNPQLAGVAPGYGIDALAIDEFTLGSKAPTIKG
IKSYTKTGKNTVEMDWSFAFTPSDVSDMTATEAREKINPKISLGVTLGKSFVSKTMPI
LVEDINVAGKMRIKVEFGKAFPNIKIVSLQLLEPPLIDFALKPIGGDTLGLDVMSFLP
GLKSFVKNIINSNIGPMLFPPNHLDINVEDIMAAQSKEAIGVLAVTIASADSLKGSDF
ITNTVDPYIVMTTEDAVPGTDEEVRTSIKSNVKNPRWNETKYLLLNTLEQKLNLKCFD
FNDVRKDTVIGDLQLDLADLLQNPVLDNQTAELRSGTKSKGILHYSLHWFPVKEDKSE
EKAVERAEAKAKGKKEDENEDTTEKEEDENEESSQTDVGIAKITLQKVKYLDTTSSMT
GSLSPCAELFIDGQKVKSYRTLRRINEPSWNETIEVLVPSKSNSKFVLKIFDDRMNGK
ALICEYSSSLDDIMTTLDTAQEFVKGSPQGDIYLDVSWKSIEMTGAFAAANSVSEPIG
CIKLDVKDAIIKGDLSGVGDVDPYYTVSLNRRVLYKSIYHSDTDHPIFDNSTYVPIFS
PNQILTLEFHDYQKIGKDRFIGSVQIPTSNVFKKDPKSGKYVGNNGKEEISKLKLKDH
EHKVTESIVNVSTTFIPINLVYSPEELVNVEKLEKELKEKKKKFEATQEENEQEMEKN
PKEWEVAEIEDPFDSDEKKINRKAKLSLNELIKQKSGILSMQILEGTLSPSSAYLEIL
ADDISYPVFICMKPSQGKLNSEMANIFIRDLNYSKLHFRVSKKHIAKDSDDVISETSY
STLKLLKQAYEEPMWLNFNGSKMKVRFLYTPTSVKLPSSESVEDTGYLNIKLISGHGL
KSADRNGYSDPFVHIFVNDKKVFKSNIKKKTLDPVWNEDAKIPILSRSKNQVIFNVLD
WDRAGDNDDLGQASLDVSSLEVGKTYNWNLNLNTQGSIKLQGSFNPEYIKPSFDIVKG
GITDKPMKIASGAAHATVGIAGTGIGAATGVATGGLKKGGHLLKSLGGNPMKRSKSSN
GNESNGAKKSSEKKSFDRRSPSNLNSTSVTPRASLDYDPSVPNTSYAPVQSASPVVKP
TDNTSSSSNKKDTPSSNSRGHSRASSFARTLAPHGTYNGFITVVAAENVAKHVQIKIS
LTQGGRLKHIYKTKSQKANNDGVAVFDEECSFKASPEANLVLGAISHQRLSRDKDLGI
AQINLGDPQIQQDGQISVKLGDGHLIVKINYGKDKNGQVPPVPEVPQEYTQ"
gene complement(129749..131572)
/gene="COG8"
/locus_tag="YML071C"
/gene_synonym="DOR1"
/db_xref="GeneID:854904"
mRNA complement(129749..131572)
/gene="COG8"
/locus_tag="YML071C"
/gene_synonym="DOR1"
/product="Cog8p"
/transcript_id="NM_001182430.1"
/db_xref="GI:296147046"
/db_xref="GeneID:854904"
CDS complement(129749..131572)
/gene="COG8"
/locus_tag="YML071C"
/gene_synonym="DOR1"
/note="Component of the conserved oligomeric Golgi complex
(Cog1p through Cog8p), a cytosolic tethering complex that
functions in protein trafficking to mediate fusion of
transport vesicles to Golgi compartments"
/codon_start=1
/product="Cog8p"
/protein_id="NP_013640.1"
/db_xref="GI:6323569"
/db_xref="SGD:S000004536"
/db_xref="GeneID:854904"
/translation="MELILNSLISDDLTEEQKRLSLDFLQDILQSNTKDYESYFSSRA
VPGSITEDIAEIDAELSALDRKIRKTLLDNTSQIIGNILENDDRAQLDDIAKSLEQLW
ELDTNINKAADRNVTNDDINNESVSIDDFLEDDKEDNDTGRIMTTESNNLARKKKEDE
FHKALSRLRNRISTKEDDKDDIRSDTLVTVLENLDSITDLMELPFLARTCIRTGHYQE
AVMLYTHTTSLRSRFPGSTIVDEVCEKVLNEISTTMLSGLVKLLSTNVSVNSLKKILQ
YLNSIPPFDGKTNKSLLSVFLAMRYKFITDEIASYPLDVESSNESLIEMMVKRKIEVL
REHVYMSLNVFLKSFLYDTNDLEIPFPEELESTVLRINGTNEEKEIEEKEKETKKEEY
QKQDSVANNEEDVTENKSIEDVQEEVQGKVEGEDDGAERKTENEIENETVNKTEDKAE
KEKEEEVNTKDNKAEKEEEEINKVEVTPEEPSKSIDNKAEKEEEEINKVEVTPEEPSK
KIRTSKRENKIPTNAVMLQFVDKCITYVLKDLTRGLNSIKLSDSVCLQLVYCSFRLCD
LNRNYHHLFLKKINDTSLFTTEQLARAIDKRAELASKYIYS"
gene complement(131825..131896)
/locus_tag="tR(UCU)M2"
/db_xref="GeneID:854905"
tRNA complement(131825..131896)
/locus_tag="tR(UCU)M2"
/product="tRNA-Arg"
/note="Arginine tRNA (tRNA-Arg), predicted by tRNAscan-SE
analysis; one of 11 nuclear tRNA genes containing the
tDNA-anticodon UCU (converted to mcm5-UCU in the mature
tRNA), decodes AGA codons into arginine, one of 19 nuclear
tRNAs for arginine"
/db_xref="SGD:S000006718"
/db_xref="GeneID:854905"
LTR complement(131989..132321)
/note="Ty1 LTR"
/db_xref="SGD:S000007101"
gene 133475..135229
/gene="DAK1"
/locus_tag="YML070W"
/db_xref="GeneID:854932"
mRNA 133475..135229
/gene="DAK1"
/locus_tag="YML070W"
/product="Dak1p"
/transcript_id="NM_001182429.1"
/db_xref="GI:296147047"
/db_xref="GeneID:854932"
CDS 133475..135229
/gene="DAK1"
/locus_tag="YML070W"
/EC_number="2.7.1.29"
/note="Dihydroxyacetone kinase, required for
detoxification of dihydroxyacetone (DHA); involved in
stress adaptation"
/codon_start=1
/product="Dak1p"
/protein_id="NP_013641.1"
/db_xref="GI:6323570"
/db_xref="SGD:S000004535"
/db_xref="GeneID:854932"
/translation="MSAKSFEVTDPVNSSLKGFALANPSITLVPEEKILFRKTDSDKI
ALISGGGSGHEPTHAGFIGKGMLSGAVVGEIFASPSTKQILNAIRLVNENASGVLLIV
KNYTGDVLHFGLSAERARALGINCRVAVIGDDVAVGREKGGMVGRRALAGTVLVHKIV
GAFAEEYSSKYGLDGTAKVAKIINDNLVTIGSSLDHCKVPGRKFESELNEKQMELGMG
IHNEPGVKVLDPIPSTEDLISKYMLPKLLDPNDKDRAFVKFDEDDEVVLLVNNLGGVS
NFVISSITSKTTDFLKENYNITPVQTIAGTLMTSFNGNGFSITLLNATKATKALQSDF
EEIKSVLDLLNAFTNAPGWPIADFEKTSAPSVNDDLLHNEVTAKAVGTYDFDKFAEWM
KSGAEQVIKSEPHITELDNQVGDGDCGYTLVAGVKGITENLDKLSKDSLSQAVAQISD
FIEGSMGGTSGGLYSILLSGFSHGLIQVCKSKDEPVTKEIVAKSLGIALDTLYKYTKA
RKGSSTMIDALEPFVKEFTASKDFNKAVKAAEEGAKSTATFEAKFGRASYVGDSSQVE
DPGAVGLCEFLKGVQSAL"
gene 135500..137158
/gene="POB3"
/locus_tag="YML069W"
/db_xref="GeneID:854933"
mRNA 135500..137158
/gene="POB3"
/locus_tag="YML069W"
/product="Pob3p"
/transcript_id="NM_001182428.1"
/db_xref="GI:296147048"
/db_xref="GeneID:854933"
CDS 135500..137158
/gene="POB3"
/locus_tag="YML069W"
/note="Subunit of the heterodimeric FACT complex
(Spt16p-Pob3p); FACT associates with chromatin via
interaction with Nhp6Ap and Nhp6Bp, and reorganizes
nucleosomes to facilitate access to DNA by RNA and DNA
polymerases; protein abundance increases in response to
DNA replication stress"
/codon_start=1
/product="Pob3p"
/protein_id="NP_013642.1"
/db_xref="GI:6323571"
/db_xref="SGD:S000004534"
/db_xref="GeneID:854933"
/translation="MSTDFDRIYLNQSKFSGRFRIADSGLGWKISTSGGSAANQARKP
FLLPATELSTVQWSRGCRGYDLKINTKNQGVIQLDGFSQDDYNLIKNDFHRRFNIQVE
QREHSLRGWNWGKTDLARNEMVFALNGKPTFEIPYARINNTNLTSKNEVGIEFNIQDE
EYQPAGDELVEMRFYIPGVIQTNVDENMTKKEESSNEVVPKKEDGAEGEDVQMAVEEK
SMAEAFYEELKEKADIGEVAGDAIVSFQDVFFTTPRGRYDIDIYKNSIRLRGKTYEYK
LQHRQIQRIVSLPKADDIHHLLVLAIEPPLRQGQTTYPFLVLQFQKDEETEVQLNLED
EDYEENYKDKLKKQYDAKTHIVLSHVLKGLTDRRVIVPGEYKSKYDQCAVSCSFKANE
GYLYPLDNAFFFLTKPTLYIPFSDVSMVNISRAGQTSTSSRTFDLEVVLRSNRGSTTF
ANISKEEQQLLEQFLKSKNLRVKNEDREVQERLQTALGSDSDEEDINMGSAGEDDESV
DEDFQVSSDNDADEVAEEFDSDAALSDAEGGSDEERPSKKPKVE"
rep_origin 137300..137548
/note="ARS1307;
Autonomously Replicating Sequence"
/db_xref="SGD:S000118367"
gene 137550..138944
/gene="ITT1"
/locus_tag="YML068W"
/db_xref="GeneID:854934"
mRNA 137550..138944
/gene="ITT1"
/locus_tag="YML068W"
/product="Itt1p"
/transcript_id="NM_001182427.1"
/db_xref="GI:296147049"
/db_xref="GeneID:854934"
CDS 137550..138944
/gene="ITT1"
/locus_tag="YML068W"
/note="Protein that modulates the efficiency of
translation termination, interacts with translation
release factors eRF1 (Sup45p) and eRF3 (Sup35p) in vitro,
contains a zinc finger domain characteristic of the TRIAD
class of proteins"
/codon_start=1
/product="Itt1p"
/protein_id="NP_013643.1"
/db_xref="GI:6323572"
/db_xref="SGD:S000004533"
/db_xref="GeneID:854934"
/translation="MALTQFENDLEILRDMYPELEMKSVKVEEEGEFPQRINGKLLFK
ISLLADVNIEFGEQHMLLSNLSNECVEFTIYSCHYPDIRRCVVMDIKSLWISTDEKKM
LIDKALRLVEETVDMSIEFADSFTSILILIFGFLIDDTAILLFPNGIRKCLTQDQYDL
FKQISEEATLQKVSRSNYHCCICMEMEKGVRMIKLPCENANVEHYLCRGCAKSYFTAM
IQENRISSVRCPQCEYKELKLEDFKSYKKMLKALFTPLIPVSFLKEVIDTELCERYEK
MFYNQAATRLSKYCPYACVTCRRCDSWCTKEDLDDAMIQCQKCHFVFCFDCLHAWHGY
NNKCGKKVSLSTDIIEEYLDDTVTSYERKRKLEAKYGRRVLELEVNDYLAEKMLDLAI
KKEGSNLQRCPKCKVVVERSEGCNKMKCEVCGTLFCFICGVLLYPEDPYEHFREAYSG
CYGRLFEGMPGTET"
gene complement(139063..140214)
/gene="ERV41"
/locus_tag="YML067C"
/db_xref="GeneID:854935"
mRNA complement(join(139063..140090,140184..140214))
/gene="ERV41"
/locus_tag="YML067C"
/product="Erv41p"
/transcript_id="NM_001182426.1"
/db_xref="GI:296147050"
/db_xref="GeneID:854935"
CDS complement(join(139063..140090,140184..140214))
/gene="ERV41"
/locus_tag="YML067C"
/note="Protein localized to COPII-coated vesicles, forms a
complex with Erv46p; involved in the membrane fusion stage
of transport; has homology to human ERGIC2 (PTX1) protein"
/codon_start=1
/product="Erv41p"
/protein_id="NP_013644.1"
/db_xref="GI:6323573"
/db_xref="SGD:S000004532"
/db_xref="GeneID:854935"
/translation="MAGLKTFDAFPKTEEQYKKKSTKGGLTSLLTYLFLLFIAWTEFG
EYFGGYIDQQYVVDSQVRDTVQINMDIYVNTKCDWLQINVRDQTMDRKLVLEELQLEE
MPFFIPYDTKVNDINEIITPELDEILGEAIPAEFREKLDTRSFFDESDPNKAHLPEFN
GCHVFGSIPVNRVSGELQITAKSLGYVASRKAPLEELKFNHVINEFSFGDFYPYIDNP
LDNTAQFNQDEPLTTYVYYTSVVPTLFKKLGAEVDTNQYSVNDYRYLYKDVAAKGDKM
PGIFFKYNFEPLSIVVSDVRLSFIQFLVRLVAICSFLVYCASWIFTLLDMALITIMGP
KWSLRYQPDDKTKGILDR"
gene complement(140424..141533)
/gene="SMA2"
/locus_tag="YML066C"
/db_xref="GeneID:854936"
mRNA complement(140424..141533)
/gene="SMA2"
/locus_tag="YML066C"
/product="Sma2p"
/transcript_id="NM_001182425.1"
/db_xref="GI:296147051"
/db_xref="GeneID:854936"
CDS complement(140424..141533)
/gene="SMA2"
/locus_tag="YML066C"
/note="Meiosis-specific prospore membrane protein;
required to produce bending force necessary for proper
assembly of the prospore membrane during sporulation"
/codon_start=1
/product="Sma2p"
/protein_id="NP_013645.1"
/db_xref="GI:6323574"
/db_xref="SGD:S000004531"
/db_xref="GeneID:854936"
/translation="MLFPKRLIVWGVLLILSLSQFVLYLPATTCTNSKGLRLCAPQFT
ITVIGGSSTANEFIASVREFLRLISYLTIDMGWSNEFTDPSVYEDENLVDTFQPDKVF
ELNYFGFCKRSNKSKVYCTSNENYGMDVLEVLVRDVGIQLGNISTTRSNETKKFGDSL
VLTYRLALTSIRDFLKHDKHTGNALSKALIGSPDPNVKGVSPTKNYLKGVNLAFILMM
FNGMVFYFAVLEIIVGFLSICVVSAFGGALSVGKRHRLFPMLLKSSSSILVVIATLTI
LCNIVYLIALKTLEPEEVTDVGSDNAAVHTTGWELLKVNVGSGFIMGLARYAIQWVLL
VLAFLAANHYKAKPKKSDKYTEDTSNSPSPDLMEK"
gene 142210..144954
/gene="ORC1"
/locus_tag="YML065W"
/db_xref="GeneID:854937"
mRNA 142210..144954
/gene="ORC1"
/locus_tag="YML065W"
/product="origin recognition complex subunit 1"
/transcript_id="NM_001182424.1"
/db_xref="GI:296147052"
/db_xref="GeneID:854937"
CDS 142210..144954
/gene="ORC1"
/locus_tag="YML065W"
/note="Largest subunit of the origin recognition complex,
which directs DNA replication by binding to replication
origins and is also involved in transcriptional silencing;
exhibits ATPase activity"
/codon_start=1
/product="origin recognition complex subunit 1"
/protein_id="NP_013646.1"
/db_xref="GI:6323575"
/db_xref="SGD:S000004530"
/db_xref="GeneID:854937"
/translation="MAKTLKDLQGWEIITTDEQGNIIDGGQKRLRRRGAKTEHYLKRS
SDGIKLGRGDSVVMHNEAAGTYSVYMIQELRLNTLNNVVELWALTYLRWFEVNPLAHY
RQFNPDANILNRPLNYYNKLFSETANKNELYLTAELAELQLFNFIRVANVMDGSKWEV
LKGNVDPERDFTVRYICEPTGEKFVDINIEDVKAYIKKVEPREAQEYLKDLTLPSKKK
EIKRGPQKKDKATQTAQISDAETRATDITDNEDGNEDESSDYESPSDIDVSEDMDSGE
ISADELEEEEDEEEDEDEEEKEARHTNSPRKRGRKIKLGKDDIDASVQPPPKKRGRKP
KDPSKPRQMLLISSCRANNTPVIRKFTKKNVARAKKKYTPFSKRFKSIAAIPDLTSLP
EFYGNSSELMASRFENKLKTTQKHQIVETIFSKVKKQLNSSYVKEEILKSANFQDYLP
ARENEFASIYLSAYSAIESDSATTIYVAGTPGVGKTLTVREVVKELLSSSAQREIPDF
LYVEINGLKMVKPTDCYETLWNKVSGERLTWAASMESLEFYFKRVPKNKKKTIVVLLD
ELDAMVTKSQDIMYNFFNWTTYENAKLIVIAVANTMDLPERQLGNKITSRIGFTRIMF
TGYTHEELKNIIDLRLKGLNDSFFYVDTKTGNAILIDAAGNDTTVKQTLPEDVRKVRL
RMSADAIEIASRKVASVSGDARRALKVCKRAAEIAEKHYMAKHGYGYDGKTVIEDENE
EQIYDDEDKDLIESNKAKDDNDDDDDNDGVQTVHITHVMKALNETLNSHVITFMTRLS
FTAKLFIYALLNLMKKNGSQEQELGDIVDEIKLLIEVNGSNKFVMEIAKTLFQQGSDN
ISEQLRIISWDFVLNQLLDAGILFKQTMKNDRICCVKLNISVEEAKRAMNEDETLRNL
"
gene complement(145139..145876)
/gene="TEM1"
/locus_tag="YML064C"
/db_xref="GeneID:854938"
mRNA complement(145139..145876)
/gene="TEM1"
/locus_tag="YML064C"
/product="Tem1p"
/transcript_id="NM_001182423.1"
/db_xref="GI:296147053"
/db_xref="GeneID:854938"
CDS complement(145139..145876)
/gene="TEM1"
/locus_tag="YML064C"
/note="GTP-binding protein of the ras superfamily involved
in termination of M-phase; controls actomyosin and septin
dynamics during cytokinesis"
/codon_start=1
/product="Tem1p"
/protein_id="NP_013647.1"
/db_xref="GI:6323576"
/db_xref="SGD:S000004529"
/db_xref="GeneID:854938"
/translation="MATPSTGANNSIPAVRNQVEVQVGLVGDAQVGKTSLMVKYVQNI
YDKEYTQTLGVNFLKRKVSIRSTDIIFSIMDLGGQREFINMLPIATVGSSVIIFLFDL
TRPETLSSIKEWYRQAYGLNDSAIPILVGTKYDLLIDLDPEYQEQISRTSMKYAQVMN
APLIFCSTAKSINIQKIFKIALAKIFNLTLTIPEINEIGDPLLIYKHLGGQQHRHHNK
SQDRKSHNIRKPSSSPSSKAPSPGVNT"
gene 146482..147249
/gene="RPS1B"
/locus_tag="YML063W"
/gene_synonym="PLC2; RP10B"
/db_xref="GeneID:854939"
mRNA 146482..147249
/gene="RPS1B"
/locus_tag="YML063W"
/gene_synonym="PLC2; RP10B"
/product="ribosomal 40S subunit protein S1B"
/transcript_id="NM_001182422.1"
/db_xref="GI:296147054"
/db_xref="GeneID:854939"
CDS 146482..147249
/gene="RPS1B"
/locus_tag="YML063W"
/gene_synonym="PLC2; RP10B"
/note="Ribosomal protein 10 (rp10) of the small (40S)
subunit; homologous to mammalian ribosomal protein S3A, no
bacterial homolog; RPS1B has a paralog, RPS1A, that arose
from the whole genome duplication"
/codon_start=1
/product="ribosomal 40S subunit protein S1B"
/protein_id="NP_013648.1"
/db_xref="GI:6323577"
/db_xref="SGD:S000004528"
/db_xref="GeneID:854939"
/translation="MAVGKNKRLSRGKKGLKKKVVDPFTRKEWFDIKAPSTFENRNVG
KTLVNKSTGLKNASDALKGRVVEVCLADLQGSEDHSFRKVKLRVDEVQGKNLLTNFHG
MDFTTDKLRSMVRKWQTLIEANVTVKTSDDYVLRIFAIAFTRKQANQVKRHSYAQSSH
IRAIRKVISEILTREVQNSTLAQLTSKLIPEVINKEIENATKDIFPLQNIHVRKVKLL
KQPKFDVGALMALHGEGSGEEKGKKVSGFKDEVLETV"
gene complement(147505..148683)
/gene="MFT1"
/locus_tag="YML062C"
/gene_synonym="MFT52"
/db_xref="GeneID:854940"
mRNA complement(147505..148683)
/gene="MFT1"
/locus_tag="YML062C"
/gene_synonym="MFT52"
/product="Mft1p"
/transcript_id="NM_001182421.1"
/db_xref="GI:296147055"
/db_xref="GeneID:854940"
CDS complement(147505..148683)
/gene="MFT1"
/locus_tag="YML062C"
/gene_synonym="MFT52"
/note="Subunit of the THO complex, which is a nuclear
complex comprised of Hpr1p, Mft1p, Rlr1p, and Thp2p, that
is involved in transcription elongation and mitotic
recombination; involved in telomere maintenance"
/codon_start=1
/product="Mft1p"
/protein_id="NP_013649.1"
/db_xref="GI:6323578"
/db_xref="SGD:S000004527"
/db_xref="GeneID:854940"
/translation="MPLSQKQIDQVRTKVHYSEVDTPFNKYLDILGKVTKLTGSIING
TLSNDDSKIEKLTEQNISQLKESAHLRFLDLQSSIDTKKVADENWETCQQETLAKLEN
LKDKLPDIKSIHSKLLLRIGKLQGLYDSVQVINREVEGLSEGRTSLVVTRAEWEKELG
TDLVKFLIEKNYLKLVDPGLKKDSSEERYRIYDDFSKGPKELESINASMKSDIENVRQ
EVSSYKEKWLRDAEIFGKITSIFKEELLKRDGLLNEAEGDNIDEDYESDEDEERKERF
KRQRSMVEVNTIENVDEKEESDHEYDDQEDEENEEEDDMEVDVEDIKEDNEVDGESSQ
QEDNSRQGNNEETDKETGVIEEPDAVNDAEEADSDHSSRKLGGTTSDFSASSSVEEVK
"
gene complement(148953..151532)
/gene="PIF1"
/locus_tag="YML061C"
/gene_synonym="TST1"
/db_xref="GeneID:854941"
mRNA complement(148953..151532)
/gene="PIF1"
/locus_tag="YML061C"
/gene_synonym="TST1"
/product="Pif1p"
/transcript_id="NM_001182420.1"
/db_xref="GI:296147056"
/db_xref="GeneID:854941"
CDS complement(148953..151532)
/gene="PIF1"
/locus_tag="YML061C"
/gene_synonym="TST1"
/EC_number="3.6.1.-"
/note="DNA helicase; exists in a nuclear form that acts as
a catalytic inhibitor of telomerase; and as a
mitochondrial form involved in repair and recombination of
mitochondrial DNA; mutations affect zinc and iron
homeostasis; regulated by Rad53p-dependent phosphorylation
in rho0 cells"
/codon_start=1
/product="Pif1p"
/protein_id="NP_013650.1"
/db_xref="GI:6323579"
/db_xref="SGD:S000004526"
/db_xref="GeneID:854941"
/translation="MPKWIRSTLNHIIPRRPFICSFNSFLLLKNVSHAKLSFSMSSRG
FRSNNFIQAQLKHPSILSKEDLDLLSDSDDWEEPDCIQLETEKQEKKIITDIHKEDPV
DKKPMRDKNVMNFINKDSPLSWNDMFKPSIIQPPQLISENSFDQSSQKKSRSTGFKNP
LRPALKKESSFDELQNNSISQERSLEMINENEKKKMQFGEKIAVLTQRPSFTELQNDQ
DDSNLNPHNGVKVKIPICLSKEQESIIKLAENGHNIFYTGSAGTGKSILLREMIKVLK
GIYGRENVAVTASTGLAACNIGGITIHSFAGIGLGKGDADKLYKKVRRSRKHLRRWEN
IGALVVDEISMLDAELLDKLDFIARKIRKNHQPFGGIQLIFCGDFFQLPPVSKDPNRP
TKFAFESKAWKEGVKMTIMLQKVFRQRGDVKFIDMLNRMRLGNIDDETEREFKKLSRP
LPDDEIIPAELYSTRMEVERANNSRLSKLPGQVHIFNAIDGGALEDEELKERLLQNFL
APKELHLKVGAQVMMVKNLDATLVNGSLGKVIEFMDPETYFCYEALTNDPSMPPEKLE
TWAENPSKLKAAMEREQSDGEESAVASRKSSVKEGFAKSDIGEPVSPLDSSVFDFMKR
VKTDDEVVLENIKRKEQLMQTIHQNSAGKRRLPLVRFKASDMSTRMVLVEPEDWAIED
ENEKPLVSRVQLPLMLAWSLSIHKSQGQTLPKVKVDLRRVFEKGQAYVALSRAVSREG
LQVLNFDRTRIKAHQKVIDFYLTLSSAESAYKQLEADEQVKKRKLDYAPGPKYKAKSK
SKSNSPAPISATTQSNNGIAAMLQRHSRKRFQLKKESNSNQVHSLVSDEPRGQDTEDH
ILE"
gene 151871..153001
/gene="OGG1"
/locus_tag="YML060W"
/db_xref="GeneID:854942"
mRNA 151871..153001
/gene="OGG1"
/locus_tag="YML060W"
/product="8-oxoguanine glycosylase OGG1"
/transcript_id="NM_001182419.1"
/db_xref="GI:296147057"
/db_xref="GeneID:854942"
CDS 151871..153001
/gene="OGG1"
/locus_tag="YML060W"
/EC_number="3.2.2.-"
/EC_number="4.2.99.18"
/note="Mitochondrial glycosylase/lyase that specifically
excises 7,8-dihydro-8-oxoguanine residues located opposite
cytosine or thymine residues in DNA, repairs oxidative
damage to mitochondrial DNA, contributes to UVA
resistance"
/codon_start=1
/product="8-oxoguanine glycosylase OGG1"
/protein_id="NP_013651.1"
/db_xref="GI:6323580"
/db_xref="SGD:S000004525"
/db_xref="GeneID:854942"
/translation="MSYKFGKLAINKSELCLANVLQAGQSFRWIWDEKLNQYSTTMKI
GQQEKYSVVILRQDEENEILEFVAVGDCGNQDALKTHLMKYFRLDVSLKHLFDNVWIP
SDKAFAKLSPQGIRILAQEPWETLISFICSSNNNISRITRMCNSLCSNFGNLITTIDG
VAYHSFPTSEELTSRATEAKLRELGFGYRAKYIIETARKLVNDKAEANITSDTTYLQS
ICKDAQYEDVREHLMSYNGVGPKVADCVCLMGLHMDGIVPVDVHVSRIAKRDYQISAN
KNHLKELRTKYNALPISRKKINLELDHIRLMLFKKWGSYAGWAQGVLFSKEIGGTSGS
TTTGTIKKRKWDMIKETEAIVTKQMKLKVELSDLHIKEAKID"
gene complement(153219..158258)
/gene="NTE1"
/locus_tag="YML059C"
/db_xref="GeneID:854943"
mRNA complement(153219..158258)
/gene="NTE1"
/locus_tag="YML059C"
/product="Nte1p"
/transcript_id="NM_001182418.1"
/db_xref="GI:296147058"
/db_xref="GeneID:854943"
CDS complement(153219..158258)
/gene="NTE1"
/locus_tag="YML059C"
/EC_number="3.1.1.5"
/note="Serine esterase, homolog of human neuropathy target
esterase (NTE); Nte1p-mediated phosphatidylcholine
turnover influences transcription factor Opi1p
localization, affecting transcriptional regulation of
phospholipid biosynthesis genes"
/codon_start=1
/product="Nte1p"
/protein_id="NP_013652.1"
/db_xref="GI:6323581"
/db_xref="SGD:S000004524"
/db_xref="GeneID:854943"
/translation="MRSMNCTTNNTNNTGQNTKNSLGSSFNSSNYTSYRFQTCLTDQI
ISEAQTWSLSSLFNFSWVVSYFVMGASRMIFRYGWYLATLSLLRIPKWIFFKLHHVQF
TLSFWLILFALAVIVFVTYTIMKERILSQYKRLTPEFLPLENTGKSGSSANINAASTQ
SANAPPAIGSSTTGASSIIDSKKHSLKDGNENETFLSSYLDQFLSAIKIFGYLEKPVF
HDLTKNMKTQKMDEGEILLLDSTIGFAIVVEGTLQLYHEVDHSDKDHGDETDHSDTDG
LDDQDRDEEDEEEDDDIDNYDTKSCSSNLIDEEDESVGYIHLKNGLGNFQLLNTVKPG
NPLTSLVSILNLFTHSMSSYGNSNFPSELSSPIDTTVSVNNMFCSSEQNFSNTDSMTN
STNSFPTFPSSMPKLVARAATDCTIGIIPPQSFAKLTAKYPRSASHIIQMVLTKLYHV
TFQTAHDYLGLTKEIMDIEVLLNKSIVYELPYYLKEAVIRKFKTVDKSSGSADLEPKP
KNSNASSKLKKPPKAKPSDGIIQSLKIANANANTSSNSLSLKPEFTHHPSSRHVVLGS
RDQFNPGDLLSNVPLSRTMDILSPNPIHNNNRNKSNGINTSTSNQHKRSSRSSSNNAS
VHSKKFSSLSPELRNAQLSTSPLSLDNTSVHDHIHPSPVHLKGRVSPRPNLLPTTSFS
AAQEETEDSALRMALVEAMLTYLGVNKSNMSVSSSSIANMSSLNSPQLNEMYSRRPSN
ASFLMSPHCTPSDISVASSFASPQTQPTMLRILPKEYTISNKRHNKSKSQDKKKPRAY
KEELTPNLDFEDVKKDFAQGIQLKFFKKGTTIVEQNARGKGLFYIISGKVNVTTNSSS
SVVSSMSKPEQVSAQSSHKGENPHHTQHLLYSVGSGGIVGYLSSLIGYKSFVNIVAKS
DVYVGFLSSATLERLFDKYFLIYLRISDSLTKLLSSRLLKLDHALEWVHLRASETLFS
QGDSANGIYVVLNGRLRQLQQQSLSNSNTSSEEVETQNIILGELAQGESFGEVEVLTA
MNRYSTIVAVRDSELARIPRTLFELLALEHPSIMIRVSRLVAKKIVGDRTVPALTGDP
LSIKENDFTSLIPPTKASYSSSLSHKPQNITSGTITFRTITILPITSGLPVEAFAMKL
VQAFKQVGRTTIGLNQRTTLTHLGRHAFDRLSKLKQSGYFAELEEMYQTVVYISDTPV
KSNWTRTCIAQGDCILLLADARSPSAEIGEYEKLLLNSKTTARTELILLHPERYVEPG
LTHKWLRYRPWVHSHHHIQFSLTGTTLMNEGKMHVLNNGALALMDKLIQTEFSRKTQQ
NISKLLPDSIKNTVENFSSRFMKSKRQYYTPVHRHKNDFLRLARILSGQAIGLVLGGG
GARGISHLGVIQAIEEQGIPVDVIGGTSIGSFVGGLYAKDYDLVPIYGRVKKFAGRIS
SIWRMLTDLTWPVTSYTTGHEFNRGIWKTFGDTRIEDFWIQYYCNSTNITDSVQEIHS
FGYAWRYIRASMSLAGLLPPLEENGSMLLDGGYVDNLPVTEMRARGCQTIFAVDVGSA
DDRTPMEYGDSLNGFWIIFNRWNPFSSHPNIPNMAEIQVRLGYVASVNALEKAKNTPG
VVYVRPPIEEYATLDFSKFEEIYHVGVDYGRIFLQGLIDDDKMPYIPGSQETTLNSQV
PEFLLHRRNSI"
gene 158760..158966
/gene="HUG1"
/locus_tag="YML058W-A"
/db_xref="GeneID:854944"
mRNA 158760..158966
/gene="HUG1"
/locus_tag="YML058W-A"
/product="Hug1p"
/transcript_id="NM_001184439.1"
/db_xref="GI:296147059"
/db_xref="GeneID:854944"
CDS 158760..158966
/gene="HUG1"
/locus_tag="YML058W-A"
/note="Protein involved in the Mec1p-mediated checkpoint
pathway; transcription is induced by DNA damage; protein
abundance increases in response to DNA replication stress"
/codon_start=1
/product="Hug1p"
/protein_id="NP_219498.1"
/db_xref="GI:15530185"
/db_xref="SGD:S000007472"
/db_xref="GeneID:854944"
/translation="MTMDQGLNPKQFFLDDVVLQDTLCSMSNRVNKSVKTGYLFPKDH
VPSANIIAVERRGGLSDIGKNTSN"
gene 159383..159697
/gene="SML1"
/locus_tag="YML058W"
/db_xref="GeneID:854945"
mRNA 159383..159697
/gene="SML1"
/locus_tag="YML058W"
/product="Sml1p"
/transcript_id="NM_001182417.1"
/db_xref="GI:296147060"
/db_xref="GeneID:854945"
CDS 159383..159697
/gene="SML1"
/locus_tag="YML058W"
/note="Ribonucleotide reductase inhibitor involved in
regulating dNTP production; regulated by Mec1p and Rad53p
during DNA damage and S phase"
/codon_start=1
/product="Sml1p"
/protein_id="NP_013653.1"
/db_xref="GI:6323582"
/db_xref="SGD:S000004523"
/db_xref="GeneID:854945"
/translation="MQNSQDYFYAQNRCQQQQAPSTLRTVTMAEFRRVPLPPMAEVPM
LSTQNSMGSSASASASSLEMWEKDLEERLNSIDHDMNNNKFGSGELKSMFNQGKVEEM
DF"
gene 160180..161994
/gene="CMP2"
/locus_tag="YML057W"
/gene_synonym="CNA2"
/db_xref="GeneID:854946"
mRNA 160180..161994
/gene="CMP2"
/locus_tag="YML057W"
/gene_synonym="CNA2"
/product="Cmp2p"
/transcript_id="NM_001182415.1"
/db_xref="GI:296147061"
/db_xref="GeneID:854946"
CDS 160180..161994
/gene="CMP2"
/locus_tag="YML057W"
/gene_synonym="CNA2"
/EC_number="3.1.3.16"
/note="Calcineurin A; one isoform (the other is CNA1) of
the catalytic subunit of calcineurin, a
Ca++/calmodulin-regulated protein phosphatase which
regulates Crz1p (a stress-response transcription factor),
the other calcineurin subunit is CNB1"
/codon_start=1
/product="Cmp2p"
/protein_id="NP_013655.1"
/db_xref="GI:6323583"
/db_xref="SGD:S000004521"
/db_xref="GeneID:854946"
/translation="MSSDAIRNTEQINAAIKIIENKTERPQSSTTPIDSKASTVAAAN
STATETSRDLTQYTLDDGRVVSTNRRIMNKVPAITSHVPTDEELFQPNGIPRHEFLRD
HFKREGKLSAAQAARIVTLATELFSKEPNLISVPAPITVCGDIHGQYFDLLKLFEVGG
DPATTSYLFLGDYVDRGSFSFECLIYLYSLKLNFNDHFWLLRGNHECKHLTSYFTFKN
EMLHKYNLDIYEKCCESFNNLPLAALMNGQYLCVHGGISPELNSLQDINNLNRFREIP
SHGLMCDLLWADPIEEYDEVLDKDLTEEDIVNSKTMVPHHGKMAPSRDMFVPNSVRGC
SYAFTYRAACHFLQETGLLSIIRAHEAQDAGYRMYKNTKTLGFPSLLTLFSAPNYLDT
YNNKAAILKYENNVMNIRQFNMTPHPYWLPDFMDVFTWSLPFVGEKVTEMLVAILNIC
TEDELENDTPVIEELVGTDKKLPQAGKSEATPQPATSASPKHASILDDEHRRKALRNK
ILAVAKVSRMYSVLREETNKVQFLKDHNSGVLPRGALSNGVKGLDEALSTFERARKHD
LINEKLPPSLDELKNENKKYYEKVWQKVHEHDAKNDSK"
gene complement(162194..164176)
/gene="IMD4"
/locus_tag="YML056C"
/db_xref="GeneID:854948"
mRNA complement(join(162194..163308,163717..164176))
/gene="IMD4"
/locus_tag="YML056C"
/product="IMP dehydrogenase IMD4"
/transcript_id="NM_001182414.1"
/db_xref="GI:296147062"
/db_xref="GeneID:854948"
CDS complement(join(162194..163308,163717..164176))
/gene="IMD4"
/locus_tag="YML056C"
/EC_number="1.1.1.205"
/note="Inosine monophosphate dehydrogenase, catalyzes the
first step of GMP biosynthesis, member of a four-gene
family in S. cerevisiae, constitutively expressed"
/codon_start=1
/product="IMP dehydrogenase IMD4"
/protein_id="NP_013656.1"
/db_xref="GI:6323585"
/db_xref="SGD:S000004520"
/db_xref="GeneID:854948"
/translation="MSAAPLDYKKALEHLKTYSSKDGLSVQELMDSTTRGGLTYNDFL
VLPGLVNFPSSAVSLQTKLTKKITLNTPFVSSPMDTVTEADMAIYMALLGGIGFIHHN
CTPKEQASMVKKVKMFENGFINSPIVISPTTTVGEVKVMKRKFGFSGFPVTEDGKCPG
KLVGLVTSRDIQFLEDDSLVVSEVMTKNPVTGIKGITLKEGNEILKQTKKGKLLIVDD
NGNLVSMLSRADLMKNQNYPLASKSATTKQLLCGAAIGTIEADKERLRLLVEAGLDVV
ILDSSQGNSVFQLNMIKWIKETFPDLEIIAGNVATREQAANLIAAGADGLRIGMGSGS
ICITQEVMACGRPQGTAVYNVCQFANQFGVPCMADGGVQNIGHITKALALGSSTVMMG
GMLAGTTESPGEYFYKDGKRLKAYRGMGSIDAMQKTGNKGNASTSRYFSESDSVLVAQ
GVSGAVVDKGSIKKFIPYLYNGLQHSCQDIGCESLTSLKENVQNGEVRFEFRTASAQL
EGGVHNLHSYEKRLYN"
gene complement(163535..163620)
/locus_tag="snR54"
/db_xref="GeneID:9164960"
ncRNA complement(163535..163620)
/locus_tag="snR54"
/ncRNA_class="snoRNA"
/product="SNR54"
/note="C/D box small nucleolar RNA (snoRNA), guides
2'-O-methylation of small subunit (SSU) rRNA at position
A974"
/db_xref="SGD:S000006445"
/db_xref="GeneID:9164960"
gene 164790..165326
/gene="SPC2"
/locus_tag="YML055W"
/gene_synonym="SPY1"
/db_xref="GeneID:854949"
mRNA 164790..165326
/gene="SPC2"
/locus_tag="YML055W"
/gene_synonym="SPY1"
/product="Spc2p"
/transcript_id="NM_001182413.1"
/db_xref="GI:296147063"
/db_xref="GeneID:854949"
CDS 164790..165326
/gene="SPC2"
/locus_tag="YML055W"
/gene_synonym="SPY1"
/note="Subunit of signal peptidase complex (Spc1p, Spc2p,
Spc3p, Sec11p), which catalyzes cleavage of N-terminal
signal sequences of proteins targeted to the secretory
pathway; homologous to mammalian SPC25"
/codon_start=1
/product="Spc2p"
/protein_id="NP_013657.1"
/db_xref="GI:6323586"
/db_xref="SGD:S000004519"
/db_xref="GeneID:854949"
/translation="MSSAKPINVYSIPELNQALDEALPSVFARLNYERSYALLDAKLY
IGYSIAVVAGLSFFLDKKFERDQIVTYQKLLVGAYFVLSLLFWYFSRFIEKGTVYVGK
RRGTKEEIYVKTKFEKNEPLYLVELVQKKKGENSKKELKAKLEVNKVFNESGYLQNDA
YFKWFSEQHNVLDTKKNE"
gene complement(165533..167308)
/gene="CYB2"
/locus_tag="YML054C"
/gene_synonym="FCB2"
/db_xref="GeneID:854950"
mRNA complement(165533..167308)
/gene="CYB2"
/locus_tag="YML054C"
/gene_synonym="FCB2"
/product="Cyb2p"
/transcript_id="NM_001182412.1"
/db_xref="GI:296147064"
/db_xref="GeneID:854950"
CDS complement(165533..167308)
/gene="CYB2"
/locus_tag="YML054C"
/gene_synonym="FCB2"
/EC_number="1.1.2.3"
/note="Cytochrome b2 (L-lactate cytochrome-c
oxidoreductase), component of the mitochondrial
intermembrane space, required for lactate utilization;
expression is repressed by glucose and anaerobic
conditions"
/codon_start=1
/product="Cyb2p"
/protein_id="NP_013658.1"
/db_xref="GI:6323587"
/db_xref="SGD:S000004518"
/db_xref="GeneID:854950"
/translation="MLKYKPLLKISKNCEAAILRASKTRLNTIRAYGSTVPKSKSFEQ
DSRKRTQSWTALRVGAILAATSSVAYLNWHNGQIDNEPKLDMNKQKISPAEVAKHNKP
DDCWVVINGYVYDLTRFLPNHPGGQDVIKFNAGKDVTAIFEPLHAPNVIDKYIAPEKK
LGPLQGSMPPELVCPPYAPGETKEDIARKEQLKSLLPPLDNIINLYDFEYLASQTLTK
QAWAYYSSGANDEVTHRENHNAYHRIFFKPKILVDVRKVDISTDMLGSHVDVPFYVSA
TALCKLGNPLEGEKDVARGCGQGVTKVPQMISTLASCSPEEIIEAAPSDKQIQWYQLY
VNSDRKITDDLVKNVEKLGVKALFVTVDAPSLGQREKDMKLKFSNTKAGPKAMKKTNV
EESQGASRALSKFIDPSLTWKDIEELKKKTKLPIVIKGVQRTEDVIKAAEIGVSGVVL
SNHGGRQLDFSRAPIEVLAETMPILEQRNLKDKLEVFVDGGVRRGTDVLKALCLGAKG
VGLGRPFLYANSCYGRNGVEKAIEILRDEIEMSMRLLGVTSIAELKPDLLDLSTLKAR
TVGVPNDVLYNEVYEGPTLTEFEDA"
gene complement(167623..167781)
/locus_tag="YML054C-A"
/db_xref="GeneID:1466497"
mRNA complement(167623..167781)
/locus_tag="YML054C-A"
/product="hypothetical protein"
/transcript_id="NM_001184571.1"
/db_xref="GI:296147065"
/db_xref="GeneID:1466497"
CDS complement(167623..167781)
/locus_tag="YML054C-A"
/codon_start=1
/product="hypothetical protein"
/protein_id="NP_878139.1"
/db_xref="GI:33438851"
/db_xref="SGD:S000028573"
/db_xref="GeneID:1466497"
/translation="MIPFPAQHEIFHAYIGRITPHSSRCIANMWHSAHFFHENSLSIM
KTLVPWTL"
LTR complement(168349..168681)
/note="Ty2 LTR"
/db_xref="SGD:S000007102"
STS 168638..168811
/standard_name="D5S559"
/db_xref="UniSTS:148320"
gene 168795..168883
/gene="SUP5"
/locus_tag="tY(GUA)M1"
/db_xref="GeneID:854951"
tRNA join(168795..168833,168848..168883)
/gene="SUP5"
/locus_tag="tY(GUA)M1"
/product="tRNA-Tyr"
/note="Tyrosine tRNA (tRNA-Tyr), predicted by tRNAscan-SE
analysis; can mutate to suppress ochre nonsense mutations"
/db_xref="SGD:S000006783"
/db_xref="GeneID:854951"
gene complement(169116..169754)
/locus_tag="YML053C"
/db_xref="GeneID:854952"
mRNA complement(169116..169754)
/locus_tag="YML053C"
/product="hypothetical protein"
/transcript_id="NM_001182411.1"
/db_xref="GI:296147066"
/db_xref="GeneID:854952"
CDS complement(169116..169754)
/locus_tag="YML053C"
/note="hypothetical protein; green fluorescent protein
(GFP)-fusion protein localizes to the cytoplasm and the
nucleus; overexpression causes a cell cycle delay or
arrest; YML053C is not an essential gene"
/codon_start=1
/product="hypothetical protein"
/protein_id="NP_013659.1"
/db_xref="GI:6323588"
/db_xref="SGD:S000004517"
/db_xref="GeneID:854952"
/translation="MLSYYEHNTAFQTNNCNSGSNAATTYNSDANNDTIMNKRKNDHF
EFDTHTFYQRSKRTKRDSVSTKFSVGSGCANLNNNNNNIIINNNNNNNNNNNNHNHNN
SNNTATYNNIHYKKNIEICPLKPVSMHHTMNSRLLNESEFYSETEEYMIHGYFGNTNR
DITGTSPTGSASIIQHQYHLLPSQSIIASQAPGTAMAALTNNNIANDYMDID"
gene 170402..171310
/gene="SUR7"
/locus_tag="YML052W"
/db_xref="GeneID:854953"
mRNA 170402..171310
/gene="SUR7"
/locus_tag="YML052W"
/product="Sur7p"
/transcript_id="NM_001182410.1"
/db_xref="GI:296147067"
/db_xref="GeneID:854953"
CDS 170402..171310
/gene="SUR7"
/locus_tag="YML052W"
/note="Plasma membrane protein that localizes to
furrow-like invaginations (MCC patches); component of
eisosomes; associated with endocytosis, along with Pil1p
and Lsp1p; sporulation and plasma membrane sphingolipid
content are altered in mutants"
/codon_start=1
/product="Sur7p"
/protein_id="NP_013660.1"
/db_xref="GI:6323589"
/db_xref="SGD:S000004516"
/db_xref="GeneID:854953"
/translation="MVKVWNIVLRLVVLLFLAGNTLLLILMIISGATDHYPVNRFYWV
QGNTTGIPNAGDETRWTFWGACLQDKDGSDTCTSNLAPAYPISPVDNFNTHINVPHQF
ISKRDAFYYLTRFSFCFFWIALAFVGVSFILYVLTWCSKMLSEMVLILMSFGFVFNTA
AVVLQTAASAMAKNAFHDDHRSAQLGASMMGMAWASVFLCIVEFILLVFWSVRARLAS
TYSIDNSRYRTSSRWNPFHREKEQATDPILTATGPEDMQQSASIVGPSSNANPVTATA
ATENQPKGINFFTIRKSHERPDDVSV"
gene 171594..172901
/gene="GAL80"
/locus_tag="YML051W"
/db_xref="GeneID:854954"
mRNA 171594..172901
/gene="GAL80"
/locus_tag="YML051W"
/product="Gal80p"
/transcript_id="NM_001182409.1"
/db_xref="GI:296147068"
/db_xref="GeneID:854954"
CDS 171594..172901
/gene="GAL80"
/locus_tag="YML051W"
/note="Transcriptional regulator involved in the
repression of GAL genes in the absence of galactose;
inhibits transcriptional activation by Gal4p; inhibition
relieved by Gal3p or Gal1p binding"
/codon_start=1
/product="Gal80p"
/protein_id="NP_013661.1"
/db_xref="GI:6323590"
/db_xref="SGD:S000004515"
/db_xref="GeneID:854954"
/translation="MDYNKRSSVSTVPNAAPIRVGFVGLNAAKGWAIKTHYPAILQLS
SQFQITALYSPKIETSIATIQRLKLSNATAFPTLESFASSSTIDMIVIAIQVASHYEV
VMPLLEFSKNNPNLKYLFVEWALACSLDQAESIYKAAAERGVQTIISLQGRKSPYILR
AKELISQGYIGDINSIEIAGNGGWYGYERPVKSPKYIYEIGNGVDLVTTTFGHTIDIL
QYMTSSYFSRINAMVFNNIPEQELIDERGNRLGQRVPKTVPDHLLFQGTLLNGNVPVS
CSFKGGKPTKKFTKNLVIDIHGTKGDLKLEGDAGFAEISNLVLYYSGTRANDFPLANG
QQAPLDPGYDAGKEIMEVYHLRNYNAIVGNIHRLYQSISDFHFNTKKIPELPSQFVMQ
GFDFEGFPTLMDALILHRLIESVYKSNMMGSTLNVSNISHYSL"
gene 173139..174074
/gene="AIM32"
/locus_tag="YML050W"
/db_xref="GeneID:854955"
mRNA 173139..174074
/gene="AIM32"
/locus_tag="YML050W"
/product="Aim32p"
/transcript_id="NM_001182408.1"
/db_xref="GI:296147069"
/db_xref="GeneID:854955"
CDS 173139..174074
/gene="AIM32"
/locus_tag="YML050W"
/note="hypothetical protein; null mutant is viable and
displays elevated frequency of mitochondrial genome loss"
/codon_start=1
/product="Aim32p"
/protein_id="NP_013662.1"
/db_xref="GI:6323591"
/db_xref="SGD:S000004514"
/db_xref="GeneID:854955"
/translation="MLRITVKTLQQRASFHHSFKHISVPDLHTRAQNDQTNCYCQEIN
ARLPSKTDPLDPHIKLPHRTPNYNKHVLLLSPGDRFAQPWKVAWNHNLDTNTNRPYNA
ISKLRSHLGGSPGILINAVHLQNEFIPRPKQHDEWLYFFVIPDMKLYVIKETDIEEFA
SFLDEGAIQAPKLSFQDYLSGKAKASQQVHEVHHRKLTRFQGETFLRDWNLVCGHYKR
DAKCGEMGPDIIAAFQDEKLFPENNLALISHIGGHIFAGNVIFYKLFGREKMQNKLDS
LWFGKVYPHNLKLLCENLENGKIIDEMYRGGISMN"
gene complement(174220..178305)
/gene="RSE1"
/locus_tag="YML049C"
/db_xref="GeneID:854956"
mRNA complement(174220..178305)
/gene="RSE1"
/locus_tag="YML049C"
/product="Rse1p"
/transcript_id="NM_001182407.1"
/db_xref="GI:296147070"
/db_xref="GeneID:854956"
CDS complement(174220..178305)
/gene="RSE1"
/locus_tag="YML049C"
/note="Protein involved in pre-mRNA splicing; component of
the pre-spliceosome; associates with U2 snRNA; involved in
ER to Golgi transport"
/codon_start=1
/product="Rse1p"
/protein_id="NP_013663.1"
/db_xref="GI:6323592"
/db_xref="SGD:S000004513"
/db_xref="GeneID:854956"
/translation="MWGGGKMAVVSLSPHTAKMRKLFGQASTTMAYDGLKREAERRTR
SDHNITMVAKDDELYLYHLTLKKQTNFVHSCIGHFVDLEAGSKREQSQLCVATETHLE
LYDTADGELKLIAKFQNLFATITSMKSLDLPHSGSRAKASNWPTFLALTSDSGNLSIV
QIIMHAGALRLKTLVNQPLTRTTLRRVSPISYMEIDPNGRCIILSSVEQNKLCFLVDY
AQKLRISSPLEIIRPHMVTLDMAVVDVNFNNPCFVTLEIDNAATQLSVHLIFYVLELG
LNHIVKKADYLVNPSANFVLSLPDLSRYNITTSLSDNNYDADYDTLFNPFVVIGFENH
ILVKDMNGFFSLKVEIPKRSITNSRHKNVTIISGIVQKLKNDFFVLLQSNHGDLFKLT
VSPDTNDRNRPLVQLSYFDTIQNSHQLHIFKNGYLFALSEMNNNFLFQFEKLGVEKND
FSNVLTSKDPNKSLVFEPSIKLQNLSILSQQLNLNPSIKSQIVSDSPLSIATKHFTNN
KIITLTNAVNYSNLISTSLPPNATKLWLIPDPATTGDNNTLLFITFPKKTMILQIDNE
SMEELTPDEATRSAFKLSQDTTIHTCLMGSHSIIQVCTAELRHIVPTGKSRYSNKLTW
VPPAGIRIVCATSSKTQLIISLSNYELVYFKIDVSSDSLIELTTHPELDTMPSKVAIV
QDTQHADLLAIADNEGMIKIMSLKDQKEDFLTVISLQLVSEKISDMIMVRDSSIGQLN
LHVGLENGVYMKFHIGDVDGSFTDIKRRFLGLKPVSLSYLREISVSLNNEEEEEEEED
DDDEKEEEEINSSGAKWMSCVVCHSSSTWVSYTWKNVWTIRQLKDQNMLSCSKFVNAD
VAINGVCSISSSGRLNIGRVSNFPTLDNWFHVHESSVNKQENGGGDESNEEEEDEMEE
EMEMLQISTFRPRTILSFPNNPKSILFIDNHSGKKQCRISLQIDGECLKFGSSDHLYK
ILDDIDCVSAAIIDFTRQADHLIICAGDKRLLTYKILVNKDKLSFDIELLHQTEIISP
IHAMLKFKNFLLTAMGSTIVLYGLGKKQLLRRSVTQTPVSITKIVSMHQWNYERLAVG
DIHESVTLFIWDPAGNVFIPYVDDSVKRHVTVLKFLDEATVIGADRYGNAWTLRSPPE
CEKIMSNHDPSELSNGAIKYPLDVITLQQKLPNTYDCKFKFQLLNHFFVNDIITDFHI
LDSLSNSDRPGCIYMGLQGTVGCFIPLLSKGNVFMMGNIENIMAEADDTFYLDYESRK
KNNNMRKEDDEEESGSVVLQGRHGIEDEIICEGSCSILGRDHQEYRSYYAPVRKVIDG
DLCENFLRLSLNEQEFLAKNLKSVQVEDIIQTINEVRTNYM"
gene 178426..179637
/gene="GSF2"
/locus_tag="YML048W"
/gene_synonym="ECM6"
/db_xref="GeneID:854957"
mRNA 178426..179637
/gene="GSF2"
/locus_tag="YML048W"
/gene_synonym="ECM6"
/product="Gsf2p"
/transcript_id="NM_001182405.1"
/db_xref="GI:296147071"
/db_xref="GeneID:854957"
CDS 178426..179637
/gene="GSF2"
/locus_tag="YML048W"
/gene_synonym="ECM6"
/note="ER localized integral membrane protein that may
promote secretion of certain hexose transporters,
including Gal2p; involved in glucose-dependent repression"
/codon_start=1
/product="Gsf2p"
/protein_id="NP_013664.1"
/db_xref="GI:6323593"
/db_xref="SGD:S000004511"
/db_xref="GeneID:854957"
/translation="MEIYIRLNADVEHDYAFQVSNEDTINNKIKKIFPSKTGLADLMV
LRPSIFHEKEPVKFYKSIHPGYLSEGGCLMFHYEADNEENLEELNDSKPLIDQLWPGQ
LVVPEWKLSKKNIWVYTIIMLAWLYTDLPDAISPTPGICLTNQLSRLLIPVAKHMDLP
EIAAKLEQEVQANYSSLVAQWLFFVMHIFKVGIITLFLKLGIANPISFNPYKLWSLRD
LTSPSANGAKNSGGNNNTTDLKTRLRSLGWIGAKRATYDDYQTNYYNYVIDKMGGAVA
AYRAGAIRKAAAPGIQLVAGEGFQSPLEDRFTASTFTAIKTERKFILSEEYFVELENN
LKKILEEYDGDIGKMNAEIRRFRRFGIYEPDEKLASLVKLRREIADEKEKASNNDATF
GIKKNDLKKSN"
gene complement(180017..181075)
/gene="PRM6"
/locus_tag="YML047C"
/gene_synonym="KCH2"
/db_xref="GeneID:854959"
mRNA complement(180017..181075)
/gene="PRM6"
/locus_tag="YML047C"
/gene_synonym="KCH2"
/product="Prm6p"
/transcript_id="NM_001182404.1"
/db_xref="GI:296147072"
/db_xref="GeneID:854959"
CDS complement(180017..181075)
/gene="PRM6"
/locus_tag="YML047C"
/gene_synonym="KCH2"
/note="Potassium transporter that mediates K+ influx;
activates the high-affinity Ca2+ influx system (HACS)
during the mating pheromone response; expression is
up-regulated in response to alpha factor; regulated by
Ste12p during mating; localized to sites of polarized
growth; similar to Prm6p; member of a fungal-specific gene
family"
/codon_start=1
/product="Prm6p"
/protein_id="NP_013666.1"
/db_xref="GI:6323595"
/db_xref="SGD:S000004510"
/db_xref="GeneID:854959"
/translation="MESSLQKLKFQDIDINLIPTAKWTTKLQYILYTWCQSILHVAMF
FSDIYTCIKLLAFNTWSNNIIQPFLEFRISKWLFSGCILCSSLILIWELVIGLRVYRK
KEITSNYMNGISRLINCLFNFKKYQIFELIVLTDEKKFSKWLFFSYFEISGCLRLLFG
DSPRQIINGLTLWSVLLTVSNETSSGTHSTQSLGNLDDLNGIINKIKHIAKTNYEESV
ILSFMLFSFIIWVILISKLILSIIIFIIFIRPRFLSSKRKVKGYELKLRKYVSKVIDE
NLSRTVYELGILIDDEEEGTICGDNKTQKKFDYDSPDYGDESTIPSYYCYSDVETYER
VYTPIKAYFPQKYKHKYI"
gene 181474..183363
/gene="PRP39"
/locus_tag="YML046W"
/db_xref="GeneID:854960"
mRNA 181474..183363
/gene="PRP39"
/locus_tag="YML046W"
/product="Prp39p"
/transcript_id="NM_001182403.1"
/db_xref="GI:296147073"
/db_xref="GeneID:854960"
CDS 181474..183363
/gene="PRP39"
/locus_tag="YML046W"
/note="U1 snRNP protein involved in splicing, contains
multiple tetriatricopeptide repeats"
/codon_start=1
/product="Prp39p"
/protein_id="NP_013667.1"
/db_xref="GI:6323596"
/db_xref="SGD:S000004509"
/db_xref="GeneID:854960"
/translation="MPDETNFTIEDIEPRPDALRGLDTQFLQDNTALVQAYRGLDWSD
ISSLTQMVDVIEQTVVKYGNPNDSIKLALETILWQILRKYPLLFGFWKRFATIEYQLF
GLKKSIAVLATSVKWFPTSLELWCDYLNVLCVNNPNETDFIRNNFEIAKDLIGKQFLS
HPFWDKFIEFEVGQKNWHNVQRIYEYIIEVPLHQYARFFTSYKKFLNEKNLKTTRNID
IVLRKTQTTVNEIWQFESKIKQPFFNLGQVLNDDLENWSRYLKFVTDPSKSLDKEFVM
SVFDRCLIPCLYHENTWMMYIKWLTKKNISDEVVVDIYQKANTFLPLDFKTLRYDFLR
FLKRKYRSNNTLFNNIFNETVSRYLKIWPNDILLMTEYLCMLKRHSFKNSLDQSPKEI
LEKQTSFTKILETSITNYINNQIDAKVHLQTLINDKNLSIVVVELIKTTWLVLKNNMQ
TRKYFNLYQKNILIKNSVPFWLTYYKFEKSNVNFTKLNKFIRELGVEIYLPTTVMNDI
LTDYKTFYLTHSNIVTYESSIIDSNTFDPILYPELKMSNPKYDPVLNTTANVDWHKKT
EWKEAGHIGITTERPQISNSIIECNSGTLIQKPISLPNFRNLEKINQVKINDLYTEEF
LKEGK"
rep_origin 183794..184037
/note="ARS1308;
Autonomously Replicating Sequence"
/db_xref="SGD:S000118368"
gene complement(183898..183968)
/locus_tag="tG(GCC)M"
/db_xref="GeneID:854961"
tRNA complement(183898..183968)
/locus_tag="tG(GCC)M"
/product="tRNA-Gly"
/note="Glycine tRNA (tRNA-Gly), predicted by tRNAscan-SE
analysis"
/db_xref="SGD:S000006585"
/db_xref="GeneID:854961"
mobile_element 184170..190083
/note="YMLWTy1-1; Ty1 element, LTR retrotransposon of the
Copia (Pseudoviridae) group; contains co-transcribed genes
TYA Gag and TYB Pol, encoding proteins involved in
structure and function of virus-like particles, flanked by
two direct repeats"
/mobile_element_type="retrotransposon:YMLWTy1-1"
/db_xref="SGD:S000007107"
LTR 184170..184501
/note="Ty1 LTR"
/db_xref="SGD:S000007103"
gene 184461..189729
/locus_tag="YML045W"
/db_xref="GeneID:854963"
mRNA join(<184461..185765,185767..>189729)
/locus_tag="YML045W"
/transcript_id="NM_001182402.1"
/db_xref="GI:296147075"
/db_xref="GeneID:854963"
CDS join(184461..185765,185767..189729)
/locus_tag="YML045W"
/EC_number="2.7.7.49"
/EC_number="3.4.23.-"
/EC_number="3.1.26.4"
/EC_number="2.7.7.7"
/ribosomal_slippage
/note="Retrotransposon TYA Gag and TYB Pol genes;
transcribed/translated as one unit; polyprotein is
processed to make a nucleocapsid-like protein (Gag),
reverse transcriptase (RT), protease (PR), and integrase
(IN); similar to retroviral genes"
/codon_start=1
/product="gag-pol fusion protein"
/protein_id="NP_013668.1"
/db_xref="GI:6323597"
/db_xref="SGD:S000004508"
/db_xref="GeneID:854963"
/translation="MESQQLSNYPNISHGSACASVTSKEVHTNQDPLDVSASKIQEYD
KASTKANSQQTTTPASSAVPENLHHASPQPASVPPPQNGPYPQQCMMTQNQANPSGWS
FYGHPSMIPYTPYQMSPMYFPPGPQSQFPQYPSSVGTPLSTPSPESGNTFTDSSSADS
DMTSTKKYVRPPPMLTSPNDFPNWVKTYIKFLQNSNLGGIIPTVNGKPVRQITDDELT
FLYNTFQIFAPSQFLPTWVKDILSVDYTDIMKILSKSIEKMQSDTQEANDIVTLANLQ
YNGSTPADAFETKVTNIIDRLNNNGIHINNKVACQLIMRGLSGEYKFLRYTRHRHLNM
TVAELFLDIHAIYEEQQGSRNSKPNYRRNPSDEKNDSRSYTNTTKPKVIARNPQKTNN
SKSKTARAHNVSTSNNSPSTDNDSISKSTTEPIQLNNKHDLHLGQKLTESTVNHTNHS
DDELPGHLLLDSGASRTLIRSAHHIHSASSNPDINVVDAQKRNIPINAIGDLQFHFQD
NTKTSIKVLHTPNIAYDLLSLNELAAVDITACFTKNVLERSDGTVLAPIVKYGDFYWV
SKKYLLPSNISVPTINNVHTSESTRKYPYPFIHRMLAHANAQTIRYSLKNNTITYFNE
SDVDWSSAIDYQCPDCLIGKSTKHRHIKGSRLKYQNSYEPFQYLHTDIFGPVHNLPKS
APSYFISFTDETTKFRWVYPLHDRREDSILDVFTTILAFIKNQFQASVLVIQMDRGSE
YTNRTLHKFLEKNGITPCYTTTADSRAHGVAERLNRTLLDDCRTQLQCSGLPNHLWFS
AIEFSTIVRNSLASPKSKKSARQHAGLAGLDISTLLPFGQPVIVNDHNPNSKIHPRGI
PGYALHPSRNSYGYIIYLPSLKKTVDTTNYVILQGKESRLDQFNYDALTFDEDLNRLT
ASYQSFIASNEIQQSDDLNIESDHDFQSDIELHPEQPRNVLSKAVSPTDSTPPSTHTE
DSKRVSKTNIRAPREVDPNISESNILPSKKRSSTPQISNIESTGSGGMHKLNVPLLAP
MSQSNTHESSHASKSKDFRHSDSYSENETNHTNVPISSTGGTNNKTVPQISDQETEKR
IIHRSPSIDASPPENNSSHNIVPIKTPTTVSEQNTEESIIADLPLPDLPPESPTEFPD
PFKELPPINSHQTNSSLGGIGDSNAYTTINSKKRSLEDNETEIKVSRDTWNTKNMRSL
EPPRSKKRIHLIAAVKAVKSIKPIRTTLRYDEAITYNKDIKEKEKYIEAYHKEVNQLL
KMNTWDTDKYYDRKEIDPKRVINSMFIFNRKRDGTHKARFVARGDIQHPDTYDSGMQS
NTVHHYALMTSLSLALDNNYYITQLDISSAYLYADIKEELYIRPPPHLGMNDKLIRLK
KSLYGLKQSGANWYETIKSYLIKQCGMEEVRGWSCVFKNSQVTICLFVDDMILFSKDL
NANKKIITTLKKQYDTKIINLGESDNEIQYDILGLEIKYQRGKYMKLGMENSLTEKIP
KLNVPLNPKGRKLSAPGQPGLYIDQDELEIDEDEYKEKVHEMQKLIGLASYVGYKFRF
DLLYYINTLAQHILFPSRQVLDMTYELIQFMWDTRDKQLIWHKNKPTEPDNKLVAISD
ASYGNQPYYKSQIGNIYLLNGKVIGGKSTKASLTCTSTTEAEIHAISESVPLLNNLSH
LVQELNKKPITKGLLTDSKSTISIIISNNEEKFRNRFFGTKAMRLRDEVSGNHLHVCY
IETKKNIADVMTKPLPIKTFKLLTNKWIH"
gene 184461..185783
/locus_tag="YML045W-A"
/db_xref="GeneID:854962"
mRNA <184461..>185783
/locus_tag="YML045W-A"
/transcript_id="NM_001184412.1"
/db_xref="GI:296147074"
/db_xref="GeneID:854962"
CDS 184461..185783
/locus_tag="YML045W-A"
/note="Retrotransposon TYA Gag gene co-transcribed with
TYB Pol; translated as TYA or TYA-TYB polyprotein; Gag is
a nucleocapsid protein that is the structural constituent
of virus-like particles (VLPs); similar to retroviral Gag"
/codon_start=1
/product="gag protein"
/protein_id="NP_058176.1"
/db_xref="GI:7839191"
/db_xref="SGD:S000007381"
/db_xref="GeneID:854962"
/translation="MESQQLSNYPNISHGSACASVTSKEVHTNQDPLDVSASKIQEYD
KASTKANSQQTTTPASSAVPENLHHASPQPASVPPPQNGPYPQQCMMTQNQANPSGWS
FYGHPSMIPYTPYQMSPMYFPPGPQSQFPQYPSSVGTPLSTPSPESGNTFTDSSSADS
DMTSTKKYVRPPPMLTSPNDFPNWVKTYIKFLQNSNLGGIIPTVNGKPVRQITDDELT
FLYNTFQIFAPSQFLPTWVKDILSVDYTDIMKILSKSIEKMQSDTQEANDIVTLANLQ
YNGSTPADAFETKVTNIIDRLNNNGIHINNKVACQLIMRGLSGEYKFLRYTRHRHLNM
TVAELFLDIHAIYEEQQGSRNSKPNYRRNPSDEKNDSRSYTNTTKPKVIARNPQKTNN
SKSKTARAHNVSTSNNSPSTDNDSISKSTTEPIQLNNKHDLHLRPETY"
LTR 189752..190083
/note="Ty1 LTR"
/db_xref="SGD:S000007104"
gene complement(190244..191767)
/gene="RRN11"
/locus_tag="YML043C"
/db_xref="GeneID:854964"
mRNA complement(190244..191767)
/gene="RRN11"
/locus_tag="YML043C"
/product="Rrn11p"
/transcript_id="NM_001182401.1"
/db_xref="GI:296147076"
/db_xref="GeneID:854964"
CDS complement(190244..191767)
/gene="RRN11"
/locus_tag="YML043C"
/note="Component of the core factor (CF) rDNA
transcription factor complex; CF is required for
transcription of 35S rRNA genes by RNA polymerase I and is
composed of Rrn6p, Rrn7p, and Rrn11p"
/codon_start=1
/product="Rrn11p"
/protein_id="NP_013669.1"
/db_xref="GI:6323598"
/db_xref="SGD:S000004507"
/db_xref="GeneID:854964"
/translation="MFEVPITLTNRKFAQRRKLKYQYINYISRRFDRISKKSTTTDSL
PTPENSAAENNDEEEGQNSEAGTYRRSVLQQKKRRRERHWRSVVGEIYSTTESETDSQ
EEETEEGGEHDTGIDKEDSDEERKFWKKYEKPEKSFEIWRTVSSQNKQPINKQKMTYH
NFKKIEKIPLRKMEIPLLHCTKENKLYFQSISRGLEPLKTSTSEVRNYRTRHIVTLTD
LLHLNVSRHNWSLAYKIFATLIRIPGVQIKSLWGIGVEILDNLSNSSSGLDFLQWMCQ
IYSSKSRFVQNINYRSIVPPFQTGSRTHTAKFAITYLWSSLINCQKSMEPSSNIIDKP
FDTENDLLQELIDKISEWVLTPPFMEDAEVWFIYASCHLLKADTLSRQFVNDNKNNDL
IGLDRDIKINQVIKHIHYVRTFLKICLDKGGFAVPSRLIENQLKSFESRLYGEAQDIQ
ERDVANVYDSIDNSSVENSFGDVYETNAEFLDTQLMDLSPEDNGLDEMHYSDEDSSE"
gene 192788..194800
/gene="CAT2"
/locus_tag="YML042W"
/gene_synonym="YCAT"
/db_xref="GeneID:854965"
mRNA 192788..194800
/gene="CAT2"
/locus_tag="YML042W"
/gene_synonym="YCAT"
/product="carnitine O-acetyltransferase CAT2"
/transcript_id="NM_001182400.1"
/db_xref="GI:296147077"
/db_xref="GeneID:854965"
CDS 192788..194800
/gene="CAT2"
/locus_tag="YML042W"
/gene_synonym="YCAT"
/EC_number="2.3.1.7"
/note="Carnitine acetyl-CoA transferase present in both
mitochondria and peroxisomes, transfers activated acetyl
groups to carnitine to form acetylcarnitine which can be
shuttled across membranes"
/codon_start=1
/product="carnitine O-acetyltransferase CAT2"
/protein_id="NP_013670.1"
/db_xref="GI:6323599"
/db_xref="SGD:S000004506"
/db_xref="GeneID:854965"
/translation="MRICHSRTLSNLKDLPITSRRAMHSAIVNYSTQKAQFPVETNNG
EHYWAEKPNKFYQNKRPNFQGITFAKQQDLPSLPVPELKSTLDKYLQTIRPFCNDVET
FERQQLLCKDFSEHMGPILQDRLKEYANDKRNWMAKFWDEQSYLQYNDPIVPYVSYFY
SHMPLPNHLSKIDNDPLIKATAIISTVVKFIEAIKDESLPVEIIKGMPFCMNSFSLMF
NTSRLPGKPEDNQDTNIFYSVYENNFVTIAYKGKFYKLMTHDGNDKPLSENEIWRQLY
SVVFQGSQSDPKLGGIGSLTSLPRDQWREVHLELMKDPISQDSLETIHKSSFMLCLDL
DQSPVTLEEKSRNCWHGDGINRFYDKSLQFLVTGNGSSGFLAEHSKMDGTPTLFLNNY
VCQQLNKLDVDDFMRKVITPSSTVAMKPMELPFIITPKIHKAIESAQLQFKETIGEHD
LRVWHYNKYGKTFIKRHGMSPDAFIQQVIQLAVFKYLKRQLPTYEAASTRKYFKGRTE
TGRSVSTASLEFVSKWQNGDVPIAEKIQALKHSAKEHSTYLKNAANGNGVDRHFFGLK
NMLKSNDDQIPPLFKDPLFNYSSTWLISTSQLSSEYFDGYGWSQVNDNGFGLAYMLNN
EWLHINIVNKPAKSGASVNRLHYYLSQAADEIFDALENENKRKAKL"
gene complement(194913..195755)
/gene="VPS71"
/locus_tag="YML041C"
/gene_synonym="SWC6"
/db_xref="GeneID:854966"
mRNA complement(194913..195755)
/gene="VPS71"
/locus_tag="YML041C"
/gene_synonym="SWC6"
/product="Vps71p"
/transcript_id="NM_001182399.1"
/db_xref="GI:296147078"
/db_xref="GeneID:854966"
CDS complement(194913..195755)
/gene="VPS71"
/locus_tag="YML041C"
/gene_synonym="SWC6"
/note="Nucleosome-binding component of the SWR1 complex,
which exchanges histone variant H2AZ (Htz1p) for
chromatin-bound histone H2A; required for vacuolar protein
sorting"
/codon_start=1
/product="Vps71p"
/protein_id="NP_013671.1"
/db_xref="GI:6323600"
/db_xref="SGD:S000004505"
/db_xref="GeneID:854966"
/translation="MKALVEEIDKKTYNPDIYFTSLDPQARRYTSKKINKQGTISTSR
PVKRINYSLADLEARLYTSRSEGDGNSISRQDDRNSKNSHSFEERYTQQEILQSDRRF
MELNTENFSDLPNVPTLLSDLTGVPRDRIESTTKPISQTSDGLSALMGGSSFVKEHSK
YGHGWVLKPETLREIQLSYKSTKLPKPKRKNTNRIVALKKVLSSKRNLHSFLDSALLN
LMDKNVIYHNVYNKRYFKVLPLITTCSICGGYDSISSCVNCGNKICSVSCFKLHNETR
CRNR"
gene complement(196068..196170)
/gene="SUF7"
/locus_tag="tP(UGG)M"
/db_xref="GeneID:854967"
tRNA complement(join(196068..196103,196135..196170))
/gene="SUF7"
/locus_tag="tP(UGG)M"
/product="tRNA-Pro"
/note="Proline tRNA (tRNA-Pro), predicted by tRNAscan-SE
analysis; target of K. lactis zymocin; can mutate to
suppress +1 frameshift mutations in proline codons"
/db_xref="SGD:S000006684"
/db_xref="GeneID:854967"
mobile_element 196332..202234
/note="YMLWTy1-2; Ty1 element, LTR retrotransposon of the
Copia (Pseudoviridae) group; contains co-transcribed genes
TYA Gag and TYB Pol, encoding proteins involved in
structure and function of virus-like particles, flanked by
two direct repeats"
/mobile_element_type="retrotransposon:YMLWTy1-2"
/db_xref="SGD:S000007108"
LTR 196332..196668
/note="Ty1 LTR"
/db_xref="SGD:S000007105"
gene 196628..201896
/locus_tag="YML039W"
/db_xref="GeneID:854969"
mRNA join(<196628..197932,197934..>201896)
/locus_tag="YML039W"
/transcript_id="NM_001182397.1"
/db_xref="GI:296147080"
/db_xref="GeneID:854969"
CDS join(196628..197932,197934..201896)
/locus_tag="YML039W"
/EC_number="2.7.7.49"
/EC_number="3.4.23.-"
/EC_number="3.1.26.4"
/EC_number="2.7.7.7"
/ribosomal_slippage
/note="Retrotransposon TYA Gag and TYB Pol genes;
transcribed/translated as one unit; polyprotein is
processed to make a nucleocapsid-like protein (Gag),
reverse transcriptase (RT), protease (PR), and integrase
(IN); similar to retroviral genes"
/codon_start=1
/product="gag-pol fusion protein"
/protein_id="NP_013672.1"
/db_xref="GI:6323601"
/db_xref="SGD:S000004503"
/db_xref="GeneID:854969"
/translation="MESQQLSQHSHISHGSACASVTSKEVHTNQDPLDVSASKTEECE
KASTKANSQQTTTPASSAVPENPHHASPQPASVPPPQNGPYPQQCMMTQNQANPSGWS
FYGHPSMIPYTPYQMSPMYFPPGPQSQFPQYPSSVGTPLSTPSPESGNTFTDSSSADS
DMTSTKKYVRPPPMLTSPNDFPNWVKTYIKFLQNSNLGGIIPTVNGKPVRQITDDELT
FLYNTFQIFAPSQFLPTWVKDILSVDYTDIMKILSKSIEKMQSDTQEANDIVTLANLQ
YNGSTPADAFETKVTNIIDRLNNNGIHINNKVACQLIMRGLSGEYKFLRYTRHRHLNM
TVAELFLDIHAIYEEQQGSRNSKPNYRRNLSDEKNDSRSYTNTTKPKVIARNPQKTNN
SKSKTARAHNVSTSNNSPSTDNDSISKSTTEPIQLNNKHDLHLGQELTESTVNHTNHS
DDELPGHLLLDSGASRTLIRSAHHIHSASSNPDINVVDAQKRNIPINAIGDLQFHFQD
NTKTSIKVLHTPNIAYDLLSLNELAAVDITACFTKNVLERSDGTVLAPIVKYGDFYWV
SKKYLLPSNISVPTINNVHTSESTRKYPYPFIHRMLAHANAQTIRYSLKNNTITYFNE
SDVDRSSAIDYQCPDCLIGKSTKHRHIKGSRLKYQNSYEPFQYLHTDIFGPVHNLPKS
APSYFISFTDETTKFRWVYPLHDRREDSILDVFTTILAFIKNQFQASVLVIQMDRGSE
YTNRTLHKFLEKNGITPCYTTTADSRAHGVAERLNRTLLDDCRTQLQCSGLPNHLWFS
AIEFSTIVRNSLASPKSKKSARQHAGLAGLDISTLLPFGQPVIVNDHNPNSKIHPRGI
PGYALHPSRNSYGYIIYLPSLKKTVDTTNYVILQGKESRLDQFNYDALTFDEDLNRLT
ASYQSFIASNEIQQSDDLNIESDHDFQSDIELHPEQPRNVLSKAVSPTDSTPPSTHTE
DSKRVSKTNIRAPREVDPNISESNILPSKKRSSTPQISNIESTGSGGMHKLNVPLLAP
MSQSNTHESSHASKSKDFRHSDSYSENETNHTNVPISSTGGTNNKTVPQISDQETEKR
IIHRSPSIDASPPENNSSHNIVPIKTPTTVSEQNTEESIIADLPLPDLPPESPTEFPD
PFKELPPINSHQTNSSLGGIGDSNAYTTINSKKRSLEDNETEIKVSRDTWNTKNMRSL
EPPRSKKRIHLIAAVKAVKSIKPIRTTLRYDEAITYNKDIKEKEKYIEAYHKEVNQLL
KMKTWDTDEYYDRKEIDPKRVINSMFIFNKKRDGTHKARFVARGDIQHPDTYDSGMQS
NTVHHYALMTSLSLALDNNYYITQLDISSAYLYADIKEELYIRPPPHLGMNDKLIRLK
KSLYGLKQSGANWYETIKSYLIKQCGMEEVRGWSCVFKNSQVTICLFVDDMILFSKDL
NANKKIITTLKKQYDTKIINLGESDNEIQYDILGLEIKYQRGKYMKLGMENSLTEKIP
KLNVPLNPKGRKLSAPGQPGLYIDQDELEIDEDEYKEKVHEMQKLIGLASYVGYKFRF
DLLYYINTLAQHILFPSRQVLDMTYELIQFMWDTRDKQLIWHKNKPTEPDNKLVAISD
ASYGNQPYYKSQIGNIYLLNGKVIGGKSTKASLTCTSTTEAEIHAISESVPLLNNLSY
LIQELNKKPIIKGLLTDSRSTISIIKSTNEEKFRNRFFGTKAMRLRDEVSGNNLYVYY
IETKKNIADVMTKPLPIKTFKLLTNKWIH"
gene 196628..197950
/locus_tag="YML040W"
/db_xref="GeneID:854968"
mRNA <196628..>197950
/locus_tag="YML040W"
/transcript_id="NM_001182398.1"
/db_xref="GI:296147079"
/db_xref="GeneID:854968"
CDS 196628..197950
/locus_tag="YML040W"
/note="Retrotransposon TYA Gag gene co-transcribed with
TYB Pol; translated as TYA or TYA-TYB polyprotein; Gag is
a nucleocapsid protein that is the structural constituent
of virus-like particles (VLPs); similar to retroviral Gag"
/codon_start=1
/product="gag protein"
/protein_id="NP_013673.1"
/db_xref="GI:6323602"
/db_xref="SGD:S000004504"
/db_xref="GeneID:854968"
/translation="MESQQLSQHSHISHGSACASVTSKEVHTNQDPLDVSASKTEECE
KASTKANSQQTTTPASSAVPENPHHASPQPASVPPPQNGPYPQQCMMTQNQANPSGWS
FYGHPSMIPYTPYQMSPMYFPPGPQSQFPQYPSSVGTPLSTPSPESGNTFTDSSSADS
DMTSTKKYVRPPPMLTSPNDFPNWVKTYIKFLQNSNLGGIIPTVNGKPVRQITDDELT
FLYNTFQIFAPSQFLPTWVKDILSVDYTDIMKILSKSIEKMQSDTQEANDIVTLANLQ
YNGSTPADAFETKVTNIIDRLNNNGIHINNKVACQLIMRGLSGEYKFLRYTRHRHLNM
TVAELFLDIHAIYEEQQGSRNSKPNYRRNLSDEKNDSRSYTNTTKPKVIARNPQKTNN
SKSKTARAHNVSTSNNSPSTDNDSISKSTTEPIQLNNKHDLHLRPGTY"
LTR 201919..202234
/note="Ty1 LTR"
/db_xref="SGD:S000007106"
gene complement(202775..204103)
/gene="YMD8"
/locus_tag="YML038C"
/db_xref="GeneID:854970"
mRNA complement(202775..204103)
/gene="YMD8"
/locus_tag="YML038C"
/product="Ymd8p"
/transcript_id="NM_001182396.1"
/db_xref="GI:296147081"
/db_xref="GeneID:854970"
CDS complement(202775..204103)
/gene="YMD8"
/locus_tag="YML038C"
/note="Putative nucleotide sugar transporter, has
similarity to Vrg4p"
/codon_start=1
/product="Ymd8p"
/protein_id="NP_013674.1"
/db_xref="GI:6323603"
/db_xref="SGD:S000004502"
/db_xref="GeneID:854970"
/translation="MNRTVFLAFVFGWYFCSIALSIYNRWMFDPKDGLGIGYPVLVTT
FHQATLWLLSGIYIKLRHKPVKNVLRKNNGFNWSFFLKFLLPTAVASAGDIGLSNVSF
QYVPLTIYTIIKSSSIAFVLLFGCIFKLEKFHWKLALSVIIMFVGVALMVFKPSDSTS
TKNDQALVIFGSFLVLASSCLSGLRWVYTQLMLRNNPIQTNTAAAVEESDGALFTENE
DNVDNEPVVNLANNKMLENFGESKPHPIHTIHQLAPIMGITLLLTSLLVEKPFPGIFS
SSIFRLDTSNGGVGTETTVLSIVRGIVLLILPGFAVFLLTICEFSILEQTPVLTVSIV
GIVKELLTVIFGIIILSERLSGFYNWLGMLIIMADVCYYNYFRYKQDLLQKYHSVSTQ
DNRNELKGFQDFEQLGSKKIAPYSISVDLTNQEYELDMIAQNVSRSSQQV"
gene complement(204386..205408)
/locus_tag="YML037C"
/db_xref="GeneID:854971"
mRNA complement(204386..205408)
/locus_tag="YML037C"
/product="hypothetical protein"
/transcript_id="NM_001182395.1"
/db_xref="GI:296147082"
/db_xref="GeneID:854971"
CDS complement(204386..205408)
/locus_tag="YML037C"
/note="hypothetical protein with some characteristics of a
transcriptional activator; may be a target of Dbf2p-Mob1p
kinase; GFP-fusion protein co-localizes with
clathrin-coated vesicles; YML037C is not an essential
gene"
/codon_start=1
/product="hypothetical protein"
/protein_id="NP_013675.1"
/db_xref="GI:6323604"
/db_xref="SGD:S000004501"
/db_xref="GeneID:854971"
/translation="MDENKIIDQLFSKEYTPQDDSEQAKNGDVSLYGLLDEVANGRRL
MNCLFHSPMQMGNKLSTDKLDGKCRQIQRDWIDEEKTITMNSGALQLDGPVLFSWSHN
VAPTSHQETINTTFKQGSPSRGSNKPKITTTSQLFDRASAEIDKCIKPNSKSWMVEER
FERNEAHTADGKKPSTWANSDFKVDPLQKFVVKELPKEKKKSDGDKTKKNKSKRKSFF
GFWGHSGSKSGSKKKSEKPIEAKNEIQDEVSQKSGLSPDDDTTFSDKNTIQSKQESMS
DQQAEPKVHEPAVTNTGCSEHDDGDGFEQVPAQSSYHPSSEPSIASTPSLTLDSFIPL
QPKKKI"
gene 205642..206293
/gene="CGI121"
/locus_tag="YML036W"
/db_xref="GeneID:854972"
mRNA join(205642..206097,206204..206293)
/gene="CGI121"
/locus_tag="YML036W"
/product="Cgi121p"
/transcript_id="NM_001182394.1"
/db_xref="GI:296147083"
/db_xref="GeneID:854972"
CDS join(205642..206097,206204..206293)
/gene="CGI121"
/locus_tag="YML036W"
/note="Component of the EKC/KEOPS complex with Bud32p,
Kae1p, Pcc1p, and Gon7p; EKC/KEOPS complex is required for
t6A tRNA modification and may have roles in telomere
maintenance and transcription; Cgi121p is dispensable for
tRNA modification"
/codon_start=1
/product="Cgi121p"
/protein_id="NP_013676.2"
/db_xref="GI:154199620"
/db_xref="SGD:S000004500"
/db_xref="GeneID:854972"
/translation="MVVSIIPQFPDIKVSLALFEQVKNAKEIRSKMSELSTSFAFIDP
RLVCSGEQMYSAIYKTLIEVKYNKMRTRNLNSECVLCLSPTSNISDAFLKFGIKDDSS
QLICLKFHTNTDDVDKEQLRTIMTSIVKGQEIEFNDDNLSRFYDEALIRKIYKLSDDF
KPQDVNGLSRALVDAIQLRGV"
gene complement(206428..208860)
/gene="AMD1"
/locus_tag="YML035C"
/gene_synonym="AMD3"
/db_xref="GeneID:854973"
mRNA complement(206428..208860)
/gene="AMD1"
/locus_tag="YML035C"
/gene_synonym="AMD3"
/product="AMP deaminase"
/transcript_id="NM_001182392.1"
/db_xref="GI:296147084"
/db_xref="GeneID:854973"
CDS complement(206428..208860)
/gene="AMD1"
/locus_tag="YML035C"
/gene_synonym="AMD3"
/EC_number="3.5.4.6"
/note="AMP deaminase; tetrameric enzyme that catalyzes the
deamination of AMP to form IMP and ammonia; thought to be
involved in regulation of intracellular purine (adenine,
guanine, and inosine) nucleotide pools"
/codon_start=1
/product="AMP deaminase"
/protein_id="NP_013677.1"
/db_xref="GI:6323606"
/db_xref="SGD:S000004498"
/db_xref="GeneID:854973"
/translation="MDNQATQRLNDLSLEPAPSHDEQDGSGLVIDIDQRKIGDEQAGV
VVDDETPPLEQQDSHESLAADSRNANFSYHENQQLLENGTKQLALDEHDSHSAILEQP
SHSTNCSSSNIAAMNKGHDSADHASQNSGGKPRTLSASAQHILPETLKSFAGAPVVNK
QVRTSASYKMGMLADDASQQFLDDPSSELIDLYSKVAECRNLRAKYQTISVQNDDQNP
KNKPGWVVYPPPPKPSYNSDTKTVVPVTNKPDAEVFDFTKCEIPGEDPDWEFTLNDDD
SYVVHRSGKTDELIAQIPTLRDYYLDLEKMISISSDGPAKSFAYRRLQYLEARWNLYY
LLNEYQETSVSKRNPHRDFYNVRKVDTHVHHSACMNQKHLLRFIKHKLRHSKDEKVIF
RDGKLLTLDEVFRSLHLTGYDLSIDTLDMHAHKDTFHRFDKFNLKYNPIGESRLREIF
LKTNNYIKGTYLADITKQVIFDLENSKYQNCEYRISVYGRSLDEWDKLASWVIDNKVI
SHNVRWLVQIPRLYDIYKKTGIVQSFQDICKNLFQPLFEVTKNPQSHPKLHVFLQRVI
GFDSVDDESKVDRRFHRKYPKPSLWEAPQNPPYSYYLYYLYSNVASLNQWRAKRGFNT
LVLRPHCGEAGDPEHLVSAYLLAHGISHGILLRKVPFVQYLYYLDQVGIAMSPLSNNA
LFLTYDKNPFPRYFKRGLNVSLSTDDPLQFSYTREPLIEEYSVAAQIYKLSNVDMCEL
ARNSVLQSGWEAQIKKHWIGKDFDKSGVEGNDVVRTNVPDIRINYRYDTLSTELELVN
HFANFKRTIEEK"
gene 209525..212155
/gene="SRC1"
/locus_tag="YML034W"
/gene_synonym="HEH1; YML033W"
/db_xref="GeneID:854974"
mRNA join(209525..211444,211571..212155)
/gene="SRC1"
/locus_tag="YML034W"
/gene_synonym="HEH1; YML033W"
/product="Src1p"
/transcript_id="NM_001182391.1"
/db_xref="GI:296147085"
/db_xref="GeneID:854974"
CDS join(209525..211444,211571..212155)
/gene="SRC1"
/locus_tag="YML034W"
/gene_synonym="HEH1; YML033W"
/note="Inner nuclear membrane protein; functions in
regulation of subtelomeric genes and is linked to TREX
(transcription export) factors; SRC1 produces 2 splice
variant proteins with different functions; alternative
splicing of SRC1 pre-mRNA is promoted by Hub1p; mutant has
aneuploidy tolerance"
/codon_start=1
/product="Src1p"
/protein_id="NP_013679.1"
/db_xref="GI:6323607"
/db_xref="SGD:S000004497"
/db_xref="GeneID:854974"
/translation="MNSDLEYLEDGFDPNSMKVATLRRILVENNVDFPSNARKNALVG
LFDEKVKPQIPQLRKMYLNVRPSDEGIVKMDRPSSSPSIASPRRSRRARREKSASPMA
KQFKKNRILDDVSNDDDDDDDDDDDNDKKDDPLIVPSGTDTDEVDDEEDDVITSSSNK
SDTNDFQQNSDTRKKRKDPDSDDWSESNSKENKIDNKHLNLLSSDSEIEQDYQKAKKR
KTSDLNQEHGNGSAILGKLSVKTPIKNTNRKPVSMDNFNDSLTSSGTENDPFVPNIRH
NPKELGTANGTGHSTPLSKLKVSASFADKLPQKEVPSTILVPEVEQQEPSQSERTPSL
FSSEGSGSESEAPLLPEITTPGPHQPMGNTSNNVVEMIDTDSSNLVSDEDEVLVPTRI
ETPQLPTEKDVEKCEARVQELQEEVNEQLEHENGSEFDVKQGSGKVGNRHKFKRALKF
LSKSLLALFLFCIFIVIPLLFGLWYREQRLLIGYCGHEVPSHRVSGNSFEFIQKLDNL
LQDYRPKCIPCPPNGICYPYLKLKCKPDYKLAPSRLDFLEIIPAQGKCVKDDKKQQLV
SEVVEKSLEFLRAKNAQISCGDGKDDIESGMTEDALYQIFNEARAPWIRDDEFEDLWI
QVIKDLTEEPEILWRQLSPTDNNIGGNSNNIIKTNDVPRQKRHLPEKFISKTRNFRST
SKKYIGMKCRFEREIYQTYKKFQRPIWLMFLLIVISKVIEIKLKNYYRKKARIEELVT
QTMEKLKFQKIKSMSDPKENAYLSIVQLRDIFLSDIVDLKYKNQLWSEVVKYLEHNNS
NIKSNLTEIRGEIMKCWEWIGPMELNEPKDSAENKI"
gene complement(212515..213930)
/gene="RAD52"
/locus_tag="YML032C"
/db_xref="GeneID:854976"
mRNA complement(212515..213930)
/gene="RAD52"
/locus_tag="YML032C"
/product="Rad52p"
/transcript_id="NM_001182390.1"
/db_xref="GI:296147086"
/db_xref="GeneID:854976"
CDS complement(212515..213930)
/gene="RAD52"
/locus_tag="YML032C"
/note="Protein that stimulates strand exchange by
facilitating Rad51p binding to single-stranded DNA;
anneals complementary single-stranded DNA; involved in the
repair of double-strand breaks in DNA during vegetative
growth and meiosis"
/codon_start=1
/product="recombinase RAD52"
/protein_id="NP_013680.2"
/db_xref="GI:27808713"
/db_xref="SGD:S000004494"
/db_xref="GeneID:854976"
/translation="MNEIMDMDEKKPVFGNHSEDIQTKLDKKLGPEYISKRVGFGTSR
IAYIEGWRVINLANQIFGYNGWSTEVKSVVIDFLDERQGKFSIGCTAIVRVTLTSGTY
REDIGYGTVENERRKPAAFERAKKSAVTDALKRSLRGFGNALGNCLYDKDFLAKIDKV
KFDPPDFDENNLFRPTDEISESSRTNTLHENQEQQQYPNKRRQLTKVTNTNPDSTKNL
VKIENTVSRGTPMMAAPAEANSKNSSNKDTDLKSLDASKQDQDDLLDDSLMFSDDFQD
DDLINMGNTNSNVLTTEKDPVVAKQSPTASSNPEAEQITFVTAKAATSVQNERYIGEE
SIFDPKYQAQSIRHTVDQTTSKHIPASVLKDKTMTTARDSVYEKFAPKGKQLSMKNND
KELGPHMLEGAGNQVPRETTPIKTNATAFPPAAAPRFAPPSKVVHPNGNGAVPAVPQQ
RSTRREVGRPKINPLHARKPT"
gene 214189..216156
/gene="NDC1"
/locus_tag="YML031W"
/db_xref="GeneID:854977"
mRNA 214189..216156
/gene="NDC1"
/locus_tag="YML031W"
/product="Ndc1p"
/transcript_id="NM_001182389.1"
/db_xref="GI:296147087"
/db_xref="GeneID:854977"
CDS 214189..216156
/gene="NDC1"
/locus_tag="YML031W"
/note="Subunit of the transmembrane ring of the nuclear
pore complex (NPC); contributes to nucleocytoplasmic
transport, NPC biogenesis and spindle pole body
duplication; homologous to human NDC1"
/codon_start=1
/product="Ndc1p"
/protein_id="NP_013681.1"
/db_xref="GI:6323610"
/db_xref="SGD:S000004493"
/db_xref="GeneID:854977"
/translation="MIQTPRELLNPRYTYHTIFSDVCKTRFNHLVTRLFFICSIIQTV
VISLLALPHSPLWELALAFIPNILALNLVSLLIIVTRKNYMHVKNFGFANSLTFILGQ
LLSVKFLVYQGVYSMGSILLSFVLGVVFGRGGSGWKPYYKLFIWLVVPTIYNLQHHVT
DADKLSFNCENFFQAPQDYVLERVKRIMEKSVILSVISMFVLPIFTTVFFSRQKSGLF
DSFTNGVLAVTNLLIISCIIFITFEFINIAFDAHMSIGCLHKGKLISNLSSTPMETLL
SGLSADKPFTRLTAYQELAYRATSLDPSLRAPIYHSKFRSSSGNTWSLILNECLKTIQ
INNEKVVQYLRSVQDLGGSATARHKKKVENLDYMYENGKLTSANERLFGNRPSMMAPL
RDNGLLDESPNRLRVRTDDSVLLNRGNKKRHRSSYYDNDLDETTQTFNGSIFTHETTF
MTAMRLMLKKLKNSIMSFIFPSYAERQSSDESDNYRLLPNGSNKAQISIIDIWSISKK
RQAEKLVPLPICHANSVVALTGLLIRSKTEDPKGGIIASVGDILKTLERSICALGEFA
DWDPESMAYTAFQTQRTAQDRVQQDSEDEDSMKDTTDMISVLYQLSTSAFMEIVLEYN
VALNDVYLDADVAKLANWFLEVYASGNPNAT"
gene 216435..216914
/gene="RCF1"
/locus_tag="YML030W"
/gene_synonym="AIM31"
/db_xref="GeneID:854978"
mRNA 216435..216914
/gene="RCF1"
/locus_tag="YML030W"
/gene_synonym="AIM31"
/product="Rcf1p"
/transcript_id="NM_001182388.1"
/db_xref="GI:296147088"
/db_xref="GeneID:854978"
CDS 216435..216914
/gene="RCF1"
/locus_tag="YML030W"
/gene_synonym="AIM31"
/note="Cytochrome c oxidase subunit; required for assembly
of the Complex III-Complex IV supercomplex, and for
assembly of Cox13p and Rcf2p into cytochrome c oxidase;
similar to Rcf2p, and either Rcf1p or Rcf2p is required
for late-stage assembly of the Cox12p and Cox13p subunits
and for cytochrome c oxidase activity; required for growth
under hypoxic conditions; member of the hypoxia induced
gene family; C. elegans and human orthologs are functional
in yeast"
/codon_start=1
/product="Rcf1p"
/protein_id="NP_013682.1"
/db_xref="GI:6323611"
/db_xref="SGD:S000004492"
/db_xref="GeneID:854978"
/translation="MSRMPSSFDVTERDLDDMTFGERIIYHCKKQPLVPIGCLLTTGA
VILAAQNVRLGNKWKAQYYFRWRVGLQAATLVALVAGSFIYGTSGKELKAKEEQLKEK
AKMREKLWIQELERREEETEARRKRAELARMKTLENEEEIKNLEKELSDLENKLGKK"
gene 217362..219878
/gene="USA1"
/locus_tag="YML029W"
/db_xref="GeneID:854979"
mRNA 217362..219878
/gene="USA1"
/locus_tag="YML029W"
/product="Usa1p"
/transcript_id="NM_001182387.1"
/db_xref="GI:296147089"
/db_xref="GeneID:854979"
CDS 217362..219878
/gene="USA1"
/locus_tag="YML029W"
/note="Scaffold subunit of the Hrd1p ubiquitin ligase that
also promotes ligase oligomerization; involved in
ER-associated protein degradation (ERAD); interacts with
the U1 snRNP-specific protein, Snp1p"
/codon_start=1
/product="Usa1p"
/protein_id="NP_013683.1"
/db_xref="GI:6323612"
/db_xref="SGD:S000004491"
/db_xref="GeneID:854979"
/translation="MSEYLAQTPCKFTIWSSEIDLIRTNLLVNAHPLSTVGRLLQYIH
YQIYKQLRAIYQPEEQCTNSEIPHTPLNSINTYFLSYEGRELSATCLLKDITSSSHPD
SNHFIRLQLEKRTSPSGSAFDLEYDMEGEFNSMNIQFEINTLSSQRIFNSMEPNLPIG
TTLARLEKLALERIKDFEKSAGNLCGIKEDHSVSDLQGFIIKGKQTPMFLNYGSDSDY
YKDLNLVDLIGIDFAPAHNSFFTFLFKMNHEQNSHIANDEERFVLEFISDATLSITQM
NVKPDTTVKQVKDFICSVYTHSLNLRRNDIKLIYKGQLLHENNFAGNSSKISEYIKEP
HEVKVHVQINQEYTESGPGFWNEVFNNPNIFQFMPPDTRSQSPVSFAPTQGRSPAAIR
GEERGIPYVTESGNDIVPTDELYRKCIINGDEVVFIPVSELNPQSSYLSVIKGDYGEI
KIPISSNDYRINGDNILLSPSAIEQLESALNFKIERPRDSTLLHPSGEHVRAADNTSS
ANDNNTVENDESAWNRRVVRPLRNSFPLLLVLIRTFYLIGYNSLVPFFIILEFGSFLP
WKYIILLSLLFIFRTVWNTQEVWNLWRDYLHLNEIDEVKFSQIKEFINSNSLTLNFYK
KCKDTQSAIDLLMIPNLHEQRLSVYSKYDIEYDTNTPDVGQLNLLFIKVLSGEIPKDA
LDELFKEFFELYETTRNMNTLYPQDSLNELLLMIWKESQKKDINTLPKYRRWFQTLCS
QIAEHNVLDVVLRYIIPDPVNDRVITAVIKNFVLFWVTLLPYVKEKLDDIVAQRARDR
EQPAPSAQQQENEDEALIIPDEEEPTATGAQPHLYIPDED"
gene 220138..220728
/gene="TSA1"
/locus_tag="YML028W"
/gene_synonym="TPX1; ZRG14"
/db_xref="GeneID:854980"
mRNA 220138..220728
/gene="TSA1"
/locus_tag="YML028W"
/gene_synonym="TPX1; ZRG14"
/product="Tsa1p"
/transcript_id="NM_001182386.1"
/db_xref="GI:296147090"
/db_xref="GeneID:854980"
CDS 220138..220728
/gene="TSA1"
/locus_tag="YML028W"
/gene_synonym="TPX1; ZRG14"
/EC_number="1.11.1.15"
/note="Thioredoxin peroxidase; acts as both a
ribosome-associated and free cytoplasmic antioxidant;
self-associates to form a high-molecular weight chaperone
complex under oxidative stress; deletion results in
mutator phenotype; protein abundance increases and forms
cytoplasmic foci in response to DNA replication stress"
/codon_start=1
/product="Tsa1p"
/protein_id="NP_013684.1"
/db_xref="GI:6323613"
/db_xref="SGD:S000004490"
/db_xref="GeneID:854980"
/translation="MVAQVQKQAPTFKKTAVVDGVFDEVSLDKYKGKYVVLAFIPLAF
TFVCPTEIIAFSEAAKKFEEQGAQVLFASTDSEYSLLAWTNIPRKEGGLGPINIPLLA
DTNHSLSRDYGVLIEEEGVALRGLFIIDPKGVIRHITINDLPVGRNVDEALRLVEAFQ
WTDKNGTVLPCNWTPGAATIKPTVEDSKEYFEAANK"
gene 221406..222563
/gene="YOX1"
/locus_tag="YML027W"
/db_xref="GeneID:854981"
mRNA 221406..222563
/gene="YOX1"
/locus_tag="YML027W"
/product="Yox1p"
/transcript_id="NM_001182385.1"
/db_xref="GI:296147091"
/db_xref="GeneID:854981"
CDS 221406..222563
/gene="YOX1"
/locus_tag="YML027W"
/note="Homeobox transcriptional repressor; binds to Mcm1p
and to early cell cycle boxes (ECBs) in the promoters of
cell cycle-regulated genes expressed in M/G1 phase;
expression is cell cycle-regulated; potential Cdc28p
substrate; YOX1 has a paralog, YHP1, that arose from the
whole genome duplication; relocalizes from nucleus to
cytoplasm upon DNA replication stress"
/codon_start=1
/product="Yox1p"
/protein_id="NP_013685.1"
/db_xref="GI:6323614"
/db_xref="SGD:S000004489"
/db_xref="GeneID:854981"
/translation="MSQETKMLPSLSSLLSGTEISSSPVSPSFTNPRTSFHLDDRGTI
KLPPLNTSINRPRSVESALRHTVTSLHENSSAYGDDMLKHTQSDSALSSQLNSSQETV
DESHENLLLTPLNSKKRDYSVSSKKNDILTPLSAAKSIIIPSASKEKRRAFAFITHSQ
ETFPKKEPKIDNAPLARRKRRRTSSQELSILQAEFEKCPAPSKEKRIELAESCHMTEK
AVQIWFQNKRQAVKRQRIATSKSTTIIQTVSPPSPPLDVHATPLASRVKADILRDGSS
CSRSSSSSPLENTPPRPHHSLNRRSSTPSIKRSQALTFHLNPQKKTLTPVKTSPNSRV
NKLINSIDHSPSKAKRPVSNPSGSPKRKRKFGFKIVDQQPLKDLDPNAFRG"
gene complement(222987..223828)
/gene="RPS18B"
/locus_tag="YML026C"
/db_xref="GeneID:854982"
mRNA complement(join(222987..223380,223782..223828))
/gene="RPS18B"
/locus_tag="YML026C"
/product="ribosomal 40S subunit protein S18B"
/transcript_id="NM_001182384.1"
/db_xref="GI:296147092"
/db_xref="GeneID:854982"
CDS complement(join(222987..223380,223782..223828))
/gene="RPS18B"
/locus_tag="YML026C"
/note="Protein component of the small (40S) ribosomal
subunit; homologous to mammalian ribosomal protein S18 and
bacterial S13; RPS18B has a paralog, RPS18A, that arose
from the whole genome duplication; protein abundance
increases in response to DNA replication stress"
/codon_start=1
/product="ribosomal 40S subunit protein S18B"
/protein_id="NP_013686.1"
/db_xref="GI:6323615"
/db_xref="SGD:S000004488"
/db_xref="GeneID:854982"
/translation="MSLVVQEQGSFQHILRLLNTNVDGNIKIVYALTTIKGVGRRYSN
LVCKKADVDLHKRAGELTQEELERIVQIMQNPTHYKIPAWFLNRQNDITDGKDYHTLA
NNVESKLRDDLERLKKIRAHRGIRHFWGLRVRGQHTKTTGRRRA"
gene complement(224406..225365)
/gene="YML6"
/locus_tag="YML025C"
/db_xref="GeneID:854983"
mRNA complement(join(224406..225239,225339..225365))
/gene="YML6"
/locus_tag="YML025C"
/product="mitochondrial 54S ribosomal protein YmL6"
/transcript_id="NM_001182383.1"
/db_xref="GI:296147093"
/db_xref="GeneID:854983"
CDS complement(join(224406..225239,225339..225365))
/gene="YML6"
/locus_tag="YML025C"
/note="Mitochondrial ribosomal protein of the large
subunit, has similarity to E. coli L4 ribosomal protein
and human mitoribosomal MRP-L4 protein; essential for
viability, unlike most other mitoribosomal proteins"
/codon_start=1
/product="mitochondrial 54S ribosomal protein YmL6"
/protein_id="NP_013687.1"
/db_xref="GI:6323616"
/db_xref="SGD:S000004487"
/db_xref="GeneID:854983"
/translation="MTIKRNLVKTLQSIRYQATTATAHAESTLNPLPNAAIPPKYALV
TVRSFPSLEPLTFVPVPTSTVAAPLRRDILWRAVVYENDNRRVGASNPPGRSENGFSR
RKLMPQKGSGRARVGDANSPTRHNGGRALARTAPNDYTTELPSKVYSMAFNNALSHQY
KSGKLFVIGGEKVDLISPTPELDLNRLDLVNTNTVEGKEIFEGEVIFRKFLEEFQLKG
KRLLFITDKTREGLIKSSDPYKQKVDVIQKELVEVNDILRAQAVFIELEALEYLAMAH
QKEILHSVSN"
gene 225889..226697
/gene="RPS17A"
/locus_tag="YML024W"
/gene_synonym="RP51A; RPL51A"
/db_xref="GeneID:854984"
mRNA join(225889..225891,226290..226697)
/gene="RPS17A"
/locus_tag="YML024W"
/gene_synonym="RP51A; RPL51A"
/product="ribosomal 40S subunit protein S17A"
/transcript_id="NM_001182382.1"
/db_xref="GI:296147094"
/db_xref="GeneID:854984"
CDS join(225889..225891,226290..226697)
/gene="RPS17A"
/locus_tag="YML024W"
/gene_synonym="RP51A; RPL51A"
/note="Ribosomal protein 51 (rp51) of the small (40s)
subunit; homologous to mammalian ribosomal protein S17, no
bacterial homolog; RPS17A has a paralog, RPS17B, that
arose from the whole genome duplication"
/codon_start=1
/product="ribosomal 40S subunit protein S17A"
/protein_id="NP_013688.1"
/db_xref="GI:6323617"
/db_xref="SGD:S000004486"
/db_xref="GeneID:854984"
/translation="MGRVRTKTVKRASKALIERYYPKLTLDFQTNKRLCDEIATIQSK
RLRNKIAGYTTHLMKRIQKGPVRGISFKLQEEERERKDQYVPEVSALDLSRSNGVLNV
DNQTSDLVKSLGLKLPLSVINVSAQRDRRYRKRV"
gene complement(226994..228664)
/gene="NSE5"
/locus_tag="YML023C"
/db_xref="GeneID:854985"
mRNA complement(226994..228664)
/gene="NSE5"
/locus_tag="YML023C"
/product="Nse5p"
/transcript_id="NM_001182381.1"
/db_xref="GI:296147095"
/db_xref="GeneID:854985"
CDS complement(226994..228664)
/gene="NSE5"
/locus_tag="YML023C"
/note="Component of the SMC5-SMC6 complex; this complex
plays a key role in the removal of X-shaped DNA structures
that arise between sister chromatids during DNA
replication and repair"
/codon_start=1
/product="Nse5p"
/protein_id="NP_013689.1"
/db_xref="GI:6323618"
/db_xref="SGD:S000004485"
/db_xref="GeneID:854985"
/translation="MDGALINSVLYVSPRNGAHYFVELTEKHLLAFEMLNSMCLLENY
DHVLLFLECQFGKSHNLAVIPFDIILVLFTLSTLSEYYKEPILRANDPYNTSRETLSR
RALKLLQKYLAILKEFDSEQYNLYDLELLRCQFFLAIDTLTPKKQKWGFDRFRRTKSE
SGVTYRQNASVDPELDQAKTFKNPYRSYISCLEQRNTILGNRLLNLKLNEPGEFINMI
LWTLSNSLQESTPLFLSSHEIWMPLLEILIDLFSCRQDYFIQHEVAQNVSKSLFVQRL
SESPLAVFFESLNTRNFANRFSEYVFLNCDYKLPSDNYATPVHPVYNGENTIVDTYIP
TIKCSPLYKSQKSLALRRKLIGSCFKLLLRVPDGHRLITPRIVADDVIQGISRTLASF
NDILQFKKFFMTENLSQESYFIPLLAEGTLSEILKDTQECVVILTLVENLSDGVSFCN
EVIGLVKSKCFAFTEQCSQASYEEAVLNIEKCDVCLLVLLRYLLHLIGTEAILDAKEQ
LEMLHAIEKNDSGRRQWAKALNLGNDPPLLYPIVSQMFGVHDKSVIIE"
gene 228937..229500
/gene="APT1"
/locus_tag="YML022W"
/db_xref="GeneID:854986"
mRNA 228937..229500
/gene="APT1"
/locus_tag="YML022W"
/product="adenine phosphoribosyltransferase APT1"
/transcript_id="NM_001182380.1"
/db_xref="GI:296147096"
/db_xref="GeneID:854986"
CDS 228937..229500
/gene="APT1"
/locus_tag="YML022W"
/EC_number="2.4.2.7"
/note="Adenine phosphoribosyltransferase; catalyzes the
formation of AMP from adenine and
5-phosphoribosylpyrophosphate; involved in the salvage
pathway of purine nucleotide biosynthesis; APT1 has a
paralog, APT2, that arose from the whole genome
duplication"
/codon_start=1
/product="adenine phosphoribosyltransferase APT1"
/protein_id="NP_013690.1"
/db_xref="GI:6323619"
/db_xref="SGD:S000004484"
/db_xref="GeneID:854986"
/translation="MSIASYAQELKLALHQYPNFPSEGILFEDFLPIFRNPGLFQKLI
DAFKLHLEEAFPEVKIDYIVGLESRGFLFGPTLALALGVGFVPVRKAGKLPGECFKAT
YEKEYGSDLFEIQKNAIPAGSNVIIVDDIIATGGSAAAAGELVEQLEANLLEYNFVME
LDFLKGRSKLNAPVFTLLNAQKEALKK"
gene complement(229734..230813)
/gene="UNG1"
/locus_tag="YML021C"
/db_xref="GeneID:854987"
mRNA complement(229734..230813)
/gene="UNG1"
/locus_tag="YML021C"
/product="Ung1p"
/transcript_id="NM_001182379.1"
/db_xref="GI:296147097"
/db_xref="GeneID:854987"
CDS complement(229734..230813)
/gene="UNG1"
/locus_tag="YML021C"
/EC_number="3.2.2.-"
/note="Uracil-DNA glycosylase, required for repair of
uracil in DNA formed by spontaneous cytosine deamination,
not required for strand-specific mismatch repair,
cell-cycle regulated, expressed in late G1, localizes to
mitochondria and nucleus"
/codon_start=1
/product="Ung1p"
/protein_id="NP_013691.1"
/db_xref="GI:6323620"
/db_xref="SGD:S000004483"
/db_xref="GeneID:854987"
/translation="MWCMRRLPTNSVMTVARKRKQTTIEDFFGTKKSTNEAPNKKGKS
GATFMTITNGAAIKTETKAVAKEANTDKYPANSNAKDVYSKNLSSNLRTLLSLELETI
DDSWFPHLMDEFKKPYFVKLKQFVTKEQADHTVFPPAKDIYSWTRLTPFNKVKVVIIG
QDPYHNFNQAHGLAFSVKPPTPAPPSLKNIYKELKQEYPDFVEDNKVGDLTHWASQGV
LLLNTSLTVRAHNANSHSKHGWETFTKRVVQLLIQDREADGKSLVFLLWGNNAIKLVE
SLLGSTSVGSGSKYPNIMVMKSVHPSPLSASRGFFGTNHFKMINDWLYNTRGEKMIDW
SVVPGTSLREVQEANARLESESKDP"
gene 231149..233143
/locus_tag="YML020W"
/db_xref="GeneID:854988"
mRNA 231149..233143
/locus_tag="YML020W"
/product="hypothetical protein"
/transcript_id="NM_001182378.1"
/db_xref="GI:296147098"
/db_xref="GeneID:854988"
CDS 231149..233143
/locus_tag="YML020W"
/codon_start=1
/product="hypothetical protein"
/protein_id="NP_013692.1"
/db_xref="GI:6323621"
/db_xref="SGD:S000004482"
/db_xref="GeneID:854988"
/translation="MVTTPLHSSPKSSLKSSTTSLRSVHTQSGRMGPSEPKHRTTKSW
SIWGGNDEEEPELSNKNKGKETAQDNSQENDNVSNEGTRLHDNQQTTILKETTRIEKG
EKDKKDRNAAIVEKNTRPRAWPFFWGRNKKDPEPTHNIPTDADNNTLSRLANSLNPAP
LTNTYIPYKPDAILIRDKGVKTAKKLTDDIGNQFPNIVVPSFDILPKQTIWNTVTSTI
WKWKTEYWDRRPSSRVREGEEQVQHSQNQLKEETNTVANEAKDEERLEHNRGSLFRVD
PWKKINLLSDYQSRPIRVLIVGVHGFFPTKIIRPFIGEPTGTSTKFVTEAEEIVKEYF
DQHKVPIEISKIALEREGEIFDRVDFFYEVMKHWSKEINNSDFIYFVSHSQGCPVTIM
LLAKLIKNGIINLDNSQFFNDEIQFCSSKKIISVLAMAGINNGPFYGADQTLFVRAYQ
TIEKDSLRELFEFQKFDSKQSQSFIEGLRTIISNNVKITFVGSINDQLVPLYSSTCLF
ANHPNIFRAIFIDRGSQTPAFITRIVKIAGSLLNLGYNDHGIIKEISGSLAGTLTGGG
HSTIYNEKQVYHLGIKFALETTDLSEMYPIEYSPYKLSELGANPYRLPWCMRGLMYES
NKHFSNEEIKMLFKEFEEWEPETKQLKDIKNRLNGLKYRL"
gene 233457..234455
/gene="OST6"
/locus_tag="YML019W"
/db_xref="GeneID:854989"
mRNA 233457..234455
/gene="OST6"
/locus_tag="YML019W"
/product="Ost6p"
/transcript_id="NM_001182377.1"
/db_xref="GI:296147099"
/db_xref="GeneID:854989"
CDS 233457..234455
/gene="OST6"
/locus_tag="YML019W"
/EC_number="2.4.99.18"
/note="Subunit of the oligosaccharyltransferase complex of
the ER lumen, which catalyzes asparagine-linked
glycosylation of newly synthesized proteins; similar to
and partially functionally redundant with Ost3p"
/codon_start=1
/product="Ost6p"
/protein_id="NP_013693.1"
/db_xref="GI:6323622"
/db_xref="SGD:S000004481"
/db_xref="GeneID:854989"
/translation="MKWCSTYIIIWLAIIFHKFQKSTATASHNIDDILQLKDDTGVIT
VTADNYPLLSRGVPGYFNILYITMRGTNSNGMSCQLCHDFEKTYHAVADVIRSQAPQS
LNLFFTVDVNEVPQLVKDLKLQNVPHLVVYPPAESNKQSQFEWKTSPFYQYSLVPENA
ENTLQFGDFLAKILNISITVPQAFNVQEFVYYFVACMVVFIFIKKVILPKVTNKWKLF
SMILSLGILLPSITGYKFVEMNAIPFIARDAKNRIMYFSGGSGWQFGIEIFSVSLMYI
VMSALSVLLIYVPKISCVSEKMRGLLSSFLACVLFYFFSYFISCYLIKNPGYPIVF"
gene complement(234771..235952)
/locus_tag="YML018C"
/db_xref="GeneID:854990"
mRNA complement(234771..235952)
/locus_tag="YML018C"
/product="hypothetical protein"
/transcript_id="NM_001182376.1"
/db_xref="GI:296147100"
/db_xref="GeneID:854990"
CDS complement(234771..235952)
/locus_tag="YML018C"
/note="hypothetical protein; green fluorescent protein
(GFP)-fusion protein localizes to the membrane of the
vacuole; physical interaction with Atg27p suggests a
possible role in autophagy; YML018C is not an essential
gene; relative distribution to the vacuolar membrane
decreases upon DNA replication stress"
/codon_start=1
/product="hypothetical protein"
/protein_id="NP_013694.1"
/db_xref="GI:6323623"
/db_xref="SGD:S000004480"
/db_xref="GeneID:854990"
/translation="MVSKDQTSFNKRWTLGLLMLGLVIILWVLSSFLINLIFEDDSYR
KPFFITYTNTAAFIFYLFPTAKAVVVNYKDTGRANVHRELIMEEEGTGSDSNRSVDMT
SPLLTNLEAGTHANQKKRLTLYETIKLSAEFCILWFTANLVTNASLAFTSVASQTILS
TTSSFFTLFIGAICHVESLSKSKVLGSFISFVGIIMVTKSDSHQRYQRHIADVSGDDN
DAVQVLIGNLLALAGAVLYGVYSTLLKREVGDETRVNMKIFFGFVGLFNLLFLWPSLI
VLDFFGWEPFSLPKDPKVVVIIFVNCLITFVSDFCWAKAMLLTSPLTVTVGLSITIPL
AMFGDVIFKHKTMSALYLFGATLILGSFFIINKSSEEEHFENSITASNYESVEVPAAN
N"
gene 236588..238731
/gene="PSP2"
/locus_tag="YML017W"
/gene_synonym="MRS15"
/db_xref="GeneID:854991"
mRNA join(236588..236591,236954..238731)
/gene="PSP2"
/locus_tag="YML017W"
/gene_synonym="MRS15"
/product="Psp2p"
/transcript_id="NM_001182375.1"
/db_xref="GI:296147101"
/db_xref="GeneID:854991"
CDS join(236588..236591,236954..238731)
/gene="PSP2"
/locus_tag="YML017W"
/gene_synonym="MRS15"
/note="Asn rich cytoplasmic protein that contains RGG
motifs; high-copy suppressor of group II intron-splicing
defects of a mutation in MRS2 and of a conditional
mutation in POL1 (DNA polymerase alpha); possible role in
mitochondrial mRNA splicing"
/codon_start=1
/product="Psp2p"
/protein_id="NP_013695.2"
/db_xref="GI:41629688"
/db_xref="SGD:S000004479"
/db_xref="GeneID:854991"
/translation="MGTNNTSNNNGTTKKMSLEEFLGNDTLGESVWDEEDINLDAISN
TTNIDILKQTKAGEHQRDGHQQHPHGGHGPMNRSRFSNAGPFGGGSMGDFANHHHPLQ
HQQGPPYIVKFSDLPPRFSNFDIEDLFQAKFTKFIKFKLFWEINKNPSISTLKSGSIF
DQNFKRDSKVAFVELYTSRDMDKILNYWTTPLKEIYHITTAPAEFEDFKDYSTKVKLL
TDPKDDAGKPFITKTQRSKSNPFGSAKPVDTQSKILDIEEKMENLHVEDTTTLRASLI
PSSDSMATTATGSKITILKKQTPTEEESHSATPTPKPLSYSEVVERSVVNETSKKGTP
LSKLDSPALELQSKPDKSDEFKGGDEQGFEKGGDDKAQLDVSNDKDKGSETDVDKQFT
FKNVEREHSMSRTKYNGNHNNNNGNFRGSNRYRGGPNGSSYKGGHNNRGNRGGYRGGS
SYNNNNNNTNDNNNNNNNSSSNNNNGSRYHDRQNNEEGLTSDSSLDASGNKKNDFTNS
TSNTQQYSIFKPASGFLGQGNNDSIRNNGRGNYNSSGMNGGSRGRGFGRGRGFGRGAY
NNRGSRGGRGSSGNYSNYNNRTTDMPL"
gene complement(239458..241536)
/gene="PPZ1"
/locus_tag="YML016C"
/db_xref="GeneID:854992"
mRNA complement(239458..241536)
/gene="PPZ1"
/locus_tag="YML016C"
/product="Ppz1p"
/transcript_id="NM_001182374.1"
/db_xref="GI:296147102"
/db_xref="GeneID:854992"
CDS complement(239458..241536)
/gene="PPZ1"
/locus_tag="YML016C"
/EC_number="3.1.3.16"
/note="Serine/threonine protein phosphatase Z, isoform of
Ppz2p; involved in regulation of potassium transport,
which affects osmotic stability, cell cycle progression,
and halotolerance"
/codon_start=1
/product="Ppz1p"
/protein_id="NP_013696.1"
/db_xref="GI:6323625"
/db_xref="SGD:S000004478"
/db_xref="GeneID:854992"
/translation="MGNSSSKSSKKDSHSNSSSRNPRPQVSRTETSHSVKSAKSNKSS
RSRRSLPSSSTTNTNSNVPDPSTPSKPNLEVNHQRHSSHTNRYHFPSSSHSHSNSQNE
LLTTPSSSSTKRPSTSRRSSYNTKAAADLPPSMIQMEPKSPILKTNNSSTHVSKHKSS
YSSTYYENALTDDDNDDKDNDISHTKRFSRSSNSRPSSIRSGSVSRRKSDVTHEEPNN
GSYSSNNQENYLVQALTRSNSHASSLHSRKSSFGSDGNTAYSTPLNSPGLSKLTDHSG
EYFTSNSTSSLNHHSSRDIYPSKHISNDDDIENSSQLSNIHASMENVNDKNNNITDSK
KDPNEEFNDIMQSSGNKNAPKKFKKPIDIDETIQKLLDAGYAAKRTKNVCLKNNEILQ
ICIKAREIFLSQPSLLELSPPVKIVGDVHGQYGDLLRLFTKCGFPPSSNYLFLGDYVD
RGKQSLETILLLFCYKIKYPENFFLLRGNHECANVTRVYGFYDECKRRCNIKIWKTFI
DTFNTLPLAAIVAGKIFCVHGGLSPVLNSMDEIRHVVRPTDVPDFGLINDLLWSDPTD
SPNEWEDNERGVSYCYNKVAINKFLNKFGFDLVCRAHMVVEDGYEFFNDRSLVTVFSA
PNYCGEFDNWGAVMSVSEGLLCSFELLDPLDSAALKQVMKKGRQERKLANQQQQMMET
SITNDNESQQ"
gene complement(241989..243029)
/gene="TAF11"
/locus_tag="YML015C"
/gene_synonym="TAF40"
/db_xref="GeneID:854993"
mRNA complement(241989..243029)
/gene="TAF11"
/locus_tag="YML015C"
/gene_synonym="TAF40"
/product="Taf11p"
/transcript_id="NM_001182373.1"
/db_xref="GI:296147103"
/db_xref="GeneID:854993"
CDS complement(241989..243029)
/gene="TAF11"
/locus_tag="YML015C"
/gene_synonym="TAF40"
/note="TFIID subunit (40 kDa), involved in RNA polymerase
II transcription initiation, similar to histone H3 with
atypical histone fold motif of Spt3-like transcription
factors"
/codon_start=1
/product="Taf11p"
/protein_id="NP_013697.1"
/db_xref="GI:6323626"
/db_xref="SGD:S000004477"
/db_xref="GeneID:854993"
/translation="MTEPQGPLDTIPKVNYPPILTIANYFSTKQMIDQVISEDQDYVT
WKLQNLRTGGTSINNQLNKYPKYKYQKTRINQQDPDSINKVPENLIFPQDILQQQTQN
SNYEDTNTNEDENEKLAQDEQFKLLVTNLDKDQTNRFEVFHRTSLNKTQVKKLASTVA
NQTISENIRVFLQAVGKIYAGEIIELAMIVKNKWLTSQMCIEFDKRTKIGYKLKKYLK
KLTFSIIENQQYKQDYQSDSVPEDEPDFYFDDEEVDKRETTLGNSLLQSKSLQQSDHN
SQDLKLQLIEQYNKLVLQFNKLDVSIEKYNNSPLLPEHIREAWRLYRLQSDTLPNAYW
RTQGEGQGSMFR"
gene 243225..244064
/gene="TRM9"
/locus_tag="YML014W"
/gene_synonym="KTI1"
/db_xref="GeneID:854994"
mRNA 243225..244064
/gene="TRM9"
/locus_tag="YML014W"
/gene_synonym="KTI1"
/product="Trm9p"
/transcript_id="NM_001182372.1"
/db_xref="GI:296147104"
/db_xref="GeneID:854994"
CDS 243225..244064
/gene="TRM9"
/locus_tag="YML014W"
/gene_synonym="KTI1"
/EC_number="2.1.1.-"
/note="tRNA methyltransferase; catalyzes modification of
wobble bases in tRNA anticodons to 2,
5-methoxycarbonylmethyluridine and
5-methoxycarbonylmethyl-2-thiouridine; may act as part of
a complex with Trm112p; deletion mutation increases
translational infidelity, including amino acid
misincorporation and -1 frameshifting, and also confers
resistance to zymocin; null mutant displays activation of
stress responses"
/codon_start=1
/product="Trm9p"
/protein_id="NP_013698.1"
/db_xref="GI:6323627"
/db_xref="SGD:S000004476"
/db_xref="GeneID:854994"
/translation="MEINQAAEKEQEYVHKVYNEIAPHFSQTRYKPWPIVTQFLKTRP
MGSIGIDVGCGNGKYLGVNPDIYIIGSDRSDGLIECARGINPSYNLLVADGLNLPHKN
ETFDFAISIAVVHHWSTRERRVEVIRHVLSKLRQGGQALIYCWALEQGSSRRGYHEGM
EQDVFVPWVLPKSKSKPKTKSTPPAKVKTRPKPNLMNIPPKERSEYLQRWKEEQQRSK
SLDDNDEKQQQDQEQEREEVKYRYYHLYREGELAEDCRQAGAAVHSEGFERDNWWVVA
QKR"
gene 244149..245903
/gene="UBX2"
/locus_tag="YML013W"
/gene_synonym="SEL1"
/db_xref="GeneID:854995"
mRNA 244149..245903
/gene="UBX2"
/locus_tag="YML013W"
/gene_synonym="SEL1"
/product="Ubx2p"
/transcript_id="NM_001182371.1"
/db_xref="GI:296147105"
/db_xref="GeneID:854995"
CDS 244149..245903
/gene="UBX2"
/locus_tag="YML013W"
/gene_synonym="SEL1"
/note="Bridging factor involved in ER-associated protein
degradation (ERAD); bridges the cytosolic
Cdc48p-Npl1p-Ufd1p ATPase complex and the membrane
associated Ssm4p and Hrd1p ubiquitin ligase complexes;
contains a UBX (ubiquitin regulatory X) domain and a
ubiquitin-associated (UBA) domain; redistributes from the
ER to lipid droplets during the diauxic shift and
stationary phase; required for the maintenance of lipid
homeostasis"
/codon_start=1
/product="Ubx2p"
/protein_id="NP_013699.1"
/db_xref="GI:6323628"
/db_xref="SGD:S000004475"
/db_xref="GeneID:854995"
/translation="MPVVNHEDSEFHLSHTEEDKLNEFQVITNFPPEDLPDVVRLLRN
HGWQLEPALSRYFDGEWKGEPDQMGEPTQTSTPMAETLVPPALGPRPLLFTASLPVVR
PLPANFRNDFRTIGLNGRSNTVWSMFESFSYDGNPFLFILLLIPRIINRLSATIFTFF
CTLLSLHSISGGGNSGKPKISKVPKAPTRETHIPLAEILGDTKDKDAFCELKSFKPDI
SFNEALRIAKEEFKFMLLILVGDTYDTDTDTVDVNSKLLLEKILLNKKTLQYLRKIDN
DLIIYLKCVHELEPWLVARQLGVRNTPEIFLIANVANKASHSETLPSQRLSILGKLKV
NSLNRFLQSLTNVVEKYTPELVVNKTEMHELRMSREIKKLQEDAYKKSLEMDRIKAIE
KEKSLKHAQDLKLNSTARQLKWLKACIDEIQPFETTGKQATLQFRTSSGKRFVKKFPS
MTTLYQIYQSIGCHIYLAVYSSDPAEWSNALQDKIRQLSADDDMLCFKEGQLETATAT
TIEELGHIINNELTSFDLERGKLEFDFELVSPFPKYTVHPNEHMSVDQVPQLWPNGSL
LVEALDEEDEEDEENEEQ"
gene 246116..246751
/gene="ERV25"
/locus_tag="YML012W"
/db_xref="GeneID:854997"
mRNA 246116..246751
/gene="ERV25"
/locus_tag="YML012W"
/product="Erv25p"
/transcript_id="NM_001182369.1"
/db_xref="GI:296147106"
/db_xref="GeneID:854997"
CDS 246116..246751
/gene="ERV25"
/locus_tag="YML012W"
/note="Protein that forms a heterotrimeric complex with
Erp1, Erp2p, and Emp24, member of the p24 family involved
in endoplasmic reticulum to Golgi transport"
/codon_start=1
/product="Erv25p"
/protein_id="NP_013701.1"
/db_xref="GI:6323630"
/db_xref="SGD:S000004473"
/db_xref="GeneID:854997"
/translation="MQVLQLWLTTLISLVVAVQGLHFDIAASTDPEQVCIRDFVTEGQ
LVVADIHSDGSVGDGQKLNLFVRDSVGNEYRRKRDFAGDVRVAFTAPSSTAFDVCFEN
QAQYRGRSLSRAIELDIESGAEARDWNKISANEKLKPIEVELRRVEEITDEIVDELTY
LKNREERLRDTNESTNRRVRNFSILVIIVLSSLGVWQVNYLKNYFKTKHII"
gene complement(246895..247428)
/gene="RAD33"
/locus_tag="YML011C"
/db_xref="GeneID:854998"
mRNA complement(246895..247428)
/gene="RAD33"
/locus_tag="YML011C"
/product="Rad33p"
/transcript_id="NM_001182368.1"
/db_xref="GI:296147107"
/db_xref="GeneID:854998"
CDS complement(246895..247428)
/gene="RAD33"
/locus_tag="YML011C"
/note="Protein involved in nucleotide excision repair;
green fluorescent protein (GFP)-fusion protein localizes
to the nucleus"
/codon_start=1
/product="Rad33p"
/protein_id="NP_013702.1"
/db_xref="GI:6323631"
/db_xref="SGD:S000004472"
/db_xref="GeneID:854998"
/translation="MSKSTNVSYERVELFENPKVPIEVEDEILEKYAESSLDHDMTVN
ELPRFFKDLQLEPTIWKLVRNEDVIIEGTDVIDFTKLVRCTCQLLILMNNLTVIDDLW
SMLIRNCGRDVDFPQVALRDHVLSVKDLQKISNLIGADQSSGTIEMISCATDGKRLFM
TYLDFGCVLGKLGYLKM"
gene 247677..250868
/gene="SPT5"
/locus_tag="YML010W"
/db_xref="GeneID:854999"
mRNA 247677..250868
/gene="SPT5"
/locus_tag="YML010W"
/product="Spt5p"
/transcript_id="NM_001182366.1"
/db_xref="GI:296147108"
/db_xref="GeneID:854999"
CDS 247677..250868
/gene="SPT5"
/locus_tag="YML010W"
/note="Component of the universally conserved Spt4/5
complex (DSIF complex); the complex has multiple roles in
concert with RNA polymerases I and II, including
regulation of transcription elongation, RNA processing,
quality control, and transcription-coupled DNA repair"
/codon_start=1
/product="Spt5p"
/protein_id="NP_013703.1"
/db_xref="GI:6323632"
/db_xref="SGD:S000004470"
/db_xref="GeneID:854999"
/translation="MSDNSDTNVSMQDHDQQFADPVVVPQSTDTKDENTSDKDTVDSG
NVTTTESTERAESTSNIPPLDGEEKEAKSEPQQPEDNAETAATEQVSSSNGPATDDAQ
ATLNTDSSEANEIVKKEEGSDERKRPREEDTKNSDGDTKDEGDNKDEDDDEDDDDDDD
DEDDDDEAPTKRRRQERNRFLDIEAEVSDDEDEDEDEEDSELVREGFITHGDDEDDEA
SAPGARRDDRLHRQLDQDLNKTSEEDAQRLAKELRERYGRSSSKQYRAAAQDGYVPQR
FLLPSVDTATIWGVRCRPGKEKELIRKLLKKKFNLDRAMGKKKLKILSIFQRDNYTGR
IYIEAPKQSVIEKFCNGVPDIYISQKLLIPVQELPLLLKPNKSDDVALEEGSYVRIKR
GIYKGDLAMVDQISENNLEVMLKIVPRLDYGKFDEIDPTTQQRKSRRPTFAHRAPPQL
FNPTMALRLDQANLYKRDDRHFTYKNEDYIDGYLYKSFRIQHVETKNIQPTVEELARF
GSKEGAVDLTSVSQSIKKAQAAKVTFQPGDRIEVLNGEQRGSKGIVTRTTKDIATIKL
NGFTTPLEFPISTLRKIFEPGDHVTVINGEHQGDAGLVLMVEQGQVTFMSTQTSREVT
ITANNLSKSIDTTATSSEYALHDIVELSAKNVACIIQAGHDIFKVIDETGKVSTITKG
SILSKINTARARVSSVDANGNEIKIGDTIVEKVGSRREGQVLYIQTQQIFVVSKKIVE
NAGVFVVNPSNVEAVASKDNMLSNKMDLSKMNPEIISKMGPPSSKTFQQPIQSRGGRE
VALGKTVRIRSAGYKGQLGIVKDVNGDKATVELHSKNKHITIDKHKLTYYNREGGEGI
TYDELVNRRGRVPQARMGPSYVSAPRNMATGGIAAGAAATSSGLSGGMTPGWSSFDGG
KTPAVNAHGGSGGGGVSSWGGASTWGGQGNGGASAWGGAGGGASAWGGQGTGATSTWG
GASAWGNKSSWGGASTWASGGESNGAMSTWGGTGDRSAYGGASTWGGNNNNKSTRDGG
ASAWGNQDDGNRSAWNNQGNKSNYGGNSTWGGH"
gene complement(251304..251516)
/gene="MRPL39"
/locus_tag="YML009C"
/db_xref="GeneID:855002"
mRNA complement(251304..251516)
/gene="MRPL39"
/locus_tag="YML009C"
/product="mitochondrial 54S ribosomal protein YmL39"
/transcript_id="NM_001182364.1"
/db_xref="GI:296147109"
/db_xref="GeneID:855002"
CDS complement(251304..251516)
/gene="MRPL39"
/locus_tag="YML009C"
/note="Mitochondrial ribosomal protein of the large
subunit"
/codon_start=1
/product="mitochondrial 54S ribosomal protein YmL39"
/protein_id="NP_013705.1"
/db_xref="GI:6323634"
/db_xref="SGD:S000004468"
/db_xref="GeneID:855002"
/translation="MVKVKSKNSVIKLLSTAASGYSRYISIKKGAPLVTQVRYDPVVK
RHVLFKEAKKRKVAERKPLDFLRTAK"
gene complement(251839..252990)
/gene="ERG6"
/locus_tag="YML008C"
/gene_synonym="ISE1; LIS1; SED6; VID1"
/db_xref="GeneID:855003"
mRNA complement(251839..252990)
/gene="ERG6"
/locus_tag="YML008C"
/gene_synonym="ISE1; LIS1; SED6; VID1"
/product="sterol 24-C-methyltransferase"
/transcript_id="NM_001182363.1"
/db_xref="GI:296147110"
/db_xref="GeneID:855003"
CDS complement(251839..252990)
/gene="ERG6"
/locus_tag="YML008C"
/gene_synonym="ISE1; LIS1; SED6; VID1"
/EC_number="2.1.1.41"
/note="Delta(24)-sterol C-methyltransferase, converts
zymosterol to fecosterol in the ergosterol biosynthetic
pathway by methylating position C-24; localized to both
lipid particles and mitochondrial outer membrane"
/codon_start=1
/product="sterol 24-C-methyltransferase"
/protein_id="NP_013706.1"
/db_xref="GI:6323635"
/db_xref="SGD:S000004467"
/db_xref="GeneID:855003"
/translation="MSETELRKRQAQFTRELHGDDIGKKTGLSALMSKNNSAQKEAVQ
KYLRNWDGRTDKDAEERRLEDYNEATHSYYNVVTDFYEYGWGSSFHFSRFYKGESFAA
SIARHEHYLAYKAGIQRGDLVLDVGCGVGGPAREIARFTGCNVIGLNNNDYQIAKAKY
YAKKYNLSDQMDFVKGDFMKMDFEENTFDKVYAIEATCHAPKLEGVYSEIYKVLKPGG
TFAVYEWVMTDKYDENNPEHRKIAYEIELGDGIPKMFHVDVARKALKNCGFEVLVSED
LADNDDEIPWYYPLTGEWKYVQNLANLATFFRTSYLGRQFTTAMVTVMEKLGLAPEGS
KEVTAALENAAVGLVAGGKSKLFTPMMLFVARKPENAETPSQTSQEATQ"
gene complement(253162..253272)
/locus_tag="YML007C-A"
/db_xref="GeneID:855004"
mRNA complement(253162..253272)
/locus_tag="YML007C-A"
/product="hypothetical protein"
/transcript_id="NM_001184487.1"
/db_xref="GI:296147111"
/db_xref="GeneID:855004"
CDS complement(253162..253272)
/locus_tag="YML007C-A"
/note="hypothetical protein; green fluorescent protein
(GFP)-fusion protein localizes to mitochondria"
/codon_start=1
/product="hypothetical protein"
/protein_id="NP_076904.1"
/db_xref="GI:13129182"
/db_xref="SGD:S000007621"
/db_xref="GeneID:855004"
/translation="MVHFIFIALRSMRFMRRLVRNLQYLLLPITSSLLFI"
gene 253848..255800
/gene="YAP1"
/locus_tag="YML007W"
/gene_synonym="PAR1; SNQ3"
/db_xref="GeneID:855005"
mRNA 253848..255800
/gene="YAP1"
/locus_tag="YML007W"
/gene_synonym="PAR1; SNQ3"
/product="Yap1p"
/transcript_id="NM_001182362.1"
/db_xref="GI:296147112"
/db_xref="GeneID:855005"
CDS 253848..255800
/gene="YAP1"
/locus_tag="YML007W"
/gene_synonym="PAR1; SNQ3"
/note="Basic leucine zipper (bZIP) transcription factor;
required for oxidative stress tolerance; activated by H2O2
through the multistep formation of disulfide bonds and
transit from the cytoplasm to the nucleus; Yap1p is
degraded in the nucleus after the oxidative stress has
passed; mediates resistance to cadmium; YAP1 has a
paralog, CAD1, that arose from the whole genome
duplication; relative distribution to the nucleus
increases upon DNA replication stress"
/codon_start=1
/product="Yap1p"
/protein_id="NP_013707.1"
/db_xref="GI:6323636"
/db_xref="SGD:S000004466"
/db_xref="GeneID:855005"
/translation="MSVSTAKRSLDVVSPGSLAEFEGSKSRHDEIENEHRRTGTRDGE
DSEQPKKKGSKTSKKQDLDPETKQKRTAQNRAAQRAFRERKERKMKELEKKVQSLESI
QQQNEVEATFLRDQLITLVNELKKYRPETRNDSKVLEYLARRDPNLHFSKNNVNHSNS
EPIDTPNDDIQENVKQKMNFTFQYPLDNDNDNDNSKNVGKQLPSPNDPSHSAPMPINQ
TQKKLSDATDSSSATLDSLSNSNDVLNNTPNSSTSMDWLDNVIYTNRFVSGDDGSNSK
TKNLDSNMFSNDFNFENQFDEQVSEFCSKMNQVCGTRQCPIPKKPISALDKEVFASSS
ILSSNSPALTNTWESHSNITDNTPANVIATDATKYENSFSGFGRLGFDMSANHYVVND
NSTGSTDSTGSTGNKNKKNNNNSDDVLPFISESPFDMNQVTNFFSPGSTGIGNNAASN
TNPSLLQSSKEDIPFINANLAFPDDNSTNIQLQPFSESQSQNKFDYDMFFRDSSKEGN
NLFGEFLEDDDDDKKAANMSDDESSLIKNQLINEEPELPKQYLQSVPGNESEISQKNG
SSLQNADKINNGNDNDNDNDVVPSKEGSLLRCSEIWDRITTHPKYSDIDVDGLCSELM
AKAKCSERGVVINAEDVQLALNKHMN"
gene complement(256092..258416)
/gene="GIS4"
/locus_tag="YML006C"
/db_xref="GeneID:855006"
mRNA complement(256092..258416)
/gene="GIS4"
/locus_tag="YML006C"
/product="Gis4p"
/transcript_id="NM_001182361.1"
/db_xref="GI:296147113"
/db_xref="GeneID:855006"
CDS complement(256092..258416)
/gene="GIS4"
/locus_tag="YML006C"
/note="CAAX box containing hypothetical protein, proposed
to be involved in the RAS/cAMP signaling pathway"
/codon_start=1
/product="Gis4p"
/protein_id="NP_013708.1"
/db_xref="GI:6323637"
/db_xref="SGD:S000004465"
/db_xref="GeneID:855006"
/translation="MQKSVRVGDYFDNDDNGLWSWYLTNLRLGDFEELIGNQLKYTLL
KRFLNSHFYGDNNISARPNKKILLVSIPENVHEDISILEIFLKDYFHLEKLEHIQISK
LTHSHCYNHENHYLLTDNLNNFQDPTFLEFASTSWQVQKNSKALNNNNRNSIPPPTIS
SSKASNGKLESNVSDDQWSNINTQTSTATRTNTNTRTLTSPDTVDINVTSVNSQSNNN
DTPQDNENEVDEEDATSSIVLNFSHSRTVDSKPNRLPKIFPSYTNEDYTPSHSEIMSI
DSFAGEDVSSTYPGQDLSLTTARREDESGQDEVEDHYSRVSHDLGDESIDQASYSMES
SVSYTSYSSSSNSSSAHYSLSSSSRGNPKRENIDHTNATYVSELSSITSSIDNLTTST
TPEEEDNLIHHNYDAQGYGSGEDDGEEVYDDEDLSSSDYSVLSILPSISICDSLGYFR
LVLQSILIQDPDTKEIFTAIRQSNNKPTMASVTDDWLLYDSNFSMNNLQILTLQDLLD
IKRSFPKILFYTMVIVTNSGKQVEEEFKNPNYDNREGISKEQPLDSELSLTNDPQQYF
PTAYNNGYNDYIDDEDDEDDGDDASLSEQSGPQMYIPTRMESNVTTAHRSIRTVNSIG
EWAFNRHNSVTKIDKSNSNELDNSKTGESTVLSSEPHPMTQLSNSNTTSSNFSHSLKT
KNSHKPNSKGNNESNSKNELKKIKSSINAMSAVERSKSLPLPTLLKSLSGIDNPTHAT
NKDRKRWKFQMNRFKNHKNSGSAGTDKSQRCAIM"
gene complement(259158..259239)
/locus_tag="tS(AGA)M"
/db_xref="GeneID:855007"
tRNA complement(259158..259239)
/locus_tag="tS(AGA)M"
/product="tRNA-Ser"
/note="Serine tRNA (tRNA-Ser), predicted by tRNAscan-SE
analysis"
/db_xref="SGD:S000006729"
/db_xref="GeneID:855007"
gene 260221..261609
/gene="TRM12"
/locus_tag="YML005W"
/gene_synonym="TYW2"
/db_xref="GeneID:855008"
mRNA 260221..261609
/gene="TRM12"
/locus_tag="YML005W"
/gene_synonym="TYW2"
/product="Trm12p"
/transcript_id="NM_001182360.1"
/db_xref="GI:296147114"
/db_xref="GeneID:855008"
CDS 260221..261609
/gene="TRM12"
/locus_tag="YML005W"
/gene_synonym="TYW2"
/EC_number="2.1.1.-"
/note="S-adenosylmethionine-dependent methyltransferase of
the seven beta-strand family; required for wybutosine
formation in phenylalanine-accepting tRNA"
/codon_start=1
/product="Trm12p"
/protein_id="NP_013709.1"
/db_xref="GI:6323638"
/db_xref="SGD:S000004464"
/db_xref="GeneID:855008"
/translation="MSDETMPVEFLVSDKRLLKTIKVKLETNGLFVTPIYSDNDNKVI
KSSIEDLNHPLAVEINNIAGVKARFHESGNLERSEGHLKHQSNSITEFTKSFLKDHGL
ANDKIFLSHLLDHLPLKYTIYPPVVLFNNSTVRSFNHPIWQKAFQLKLFDPNEYYREL
LCFLSPGKPSKGTSLHPNNRLLTHLAINNPITEADVLRRPFNIQPLYGKLIDDSILDD
NDNTLWENPSQEQLNSSIWCKVIQNGVTQIWSPVFTMFSRGNIKEKKRVLTTFPDICN
NDVVDLYAGIGYFTFSYLTKGARTLFAFELNPWSVEGLKRGLKANGFNKSGNCHVFQE
SNEMCVQRLTEFLSQNPGFRLRIRHINLGLLPSSKQGWPLAIKLIYLQGASLEKVTMH
IHENVHIDAIEDGSFEKNVIVELDAINESIALIRNRGIKLQFVRSKLERIKTFAPDIW
HVCVDVDVIVST"
gene complement(261705..262685)
/gene="GLO1"
/locus_tag="YML004C"
/db_xref="GeneID:855009"
mRNA complement(261705..262685)
/gene="GLO1"
/locus_tag="YML004C"
/product="lactoylglutathione lyase GLO1"
/transcript_id="NM_001182359.1"
/db_xref="GI:296147115"
/db_xref="GeneID:855009"
CDS complement(261705..262685)
/gene="GLO1"
/locus_tag="YML004C"
/EC_number="4.4.1.5"
/note="Monomeric glyoxalase I, catalyzes the
detoxification of methylglyoxal (a by-product of
glycolysis) via condensation with glutathione to produce
S-D-lactoylglutathione; expression regulated by
methylglyoxal levels and osmotic stress"
/codon_start=1
/product="lactoylglutathione lyase GLO1"
/protein_id="NP_013710.1"
/db_xref="GI:6323639"
/db_xref="SGD:S000004463"
/db_xref="GeneID:855009"
/translation="MSTDSTRYPIQIEKASNDPTLLLNHTCLRVKDPARTVKFYTEHF
GMKLLSRKDFEEAKFSLYFLSFPKDDIPKNKNGEPDVFSAHGVLELTHNWGTEKNPDY
KINNGNEEPHRGFGHICFSVSDINKTCEELESQGVKFKKRLSEGRQKDIAFALGPDGY
WIELITYSREGQEYPKGSVGNKFNHTMIRIKNPTRSLEFYQNVLGMKLLRTSEHESAK
FTLYFLGYGVPKTDSVFSCESVLELTHNWGTENDPNFHYHNGNSEPQGYGHICISCDD
AGALCKEIEVKYGDKIQWSPKFNQGRMKNIAFLKDPDGYSIEVVPHGLIA"
rep_origin 263063..263296
/note="ARS1309;
Autonomously Replicating Sequence"
/db_xref="SGD:S000118369"
gene 263483..264355
/locus_tag="YML003W"
/db_xref="GeneID:855010"
mRNA 263483..264355
/locus_tag="YML003W"
/product="hypothetical protein"
/transcript_id="NM_001182358.1"
/db_xref="GI:296147116"
/db_xref="GeneID:855010"
CDS 263483..264355
/locus_tag="YML003W"
/codon_start=1
/product="hypothetical protein"
/protein_id="NP_013711.1"
/db_xref="GI:6323640"
/db_xref="SGD:S000004462"
/db_xref="GeneID:855010"
/translation="MSVYHLPTLLNPLVNAIFNCPEPERSPLKKLFANLKTRRFILLA
PPSEYLLNYHDVKSKLPLHDLCYNAEFINSYILLMTENSYINTNSRDSHYETLDGKTV
VIQWKNNVIHALNGFHIRRRLKILETKILPNFNDYFEGAADFIILFIDQPLNCEFVPN
DYLQCFHNYEKIPKNAHAMPNLSIDSFQQERSSFENILHIHPARLTQLGQLFSSYRTL
APGDDPSRSIFESIVQQAFDGMKSDSLFKNFSNLYDLIHDYFELNLYDDIWSRLTTHF
KGHEVDTEKINIFQ"
gene 264541..266754
/locus_tag="YML002W"
/db_xref="GeneID:855011"
mRNA 264541..266754
/locus_tag="YML002W"
/product="hypothetical protein"
/transcript_id="NM_001182357.1"
/db_xref="GI:296147117"
/db_xref="GeneID:855011"
CDS 264541..266754
/locus_tag="YML002W"
/note="hypothetical protein; expression induced by heat
and by calcium shortage"
/codon_start=1
/product="hypothetical protein"
/protein_id="NP_013712.1"
/db_xref="GI:6323641"
/db_xref="SGD:S000004461"
/db_xref="GeneID:855011"
/translation="MDSHQLELPDGLNNMTMDADTLISLFVLVVCRSEQKHLKSHLYY
LQNFSNNSSSTKFGILGYAVSTLEAVVCYFEDFNKNTGNVAKANTLCEKTKNLLDKLS
CENPTNEVEDLATYKDILTYRNEQGQSILSICITNHKNYILLDILSEYENDFPVEDLL
EDETIDGSTLLIESIKAGNLEAAKVLIKIMLFNCTEEELVSYINKTDKYARTVAHYLT
HEMDILKSIGNYIDWKRKNSSGQTPLFSIFRSYDQPNYEEMVKTAFDIANTWYRKHNS
LFDYLDHTDNKGNSLLHVLKTNIPILLQLTKLDINEENYKGLTPLMVYVKYKRLSNID
AITKDRRLILEKVQNSTFFTCFDYAKDHSVLSKIGERGVKDSLFGLIYFHSLRYHNLN
ATTNITSVSNAEKPFATTVINMKTIQGLLRSILKDNPFTFLPLNTYIDEISHLNRSDL
TIIGKTDVTSLLHQLTNCFNVLLFLKKIPENLFTDEASILYWMRINTSKRNQKPSGKE
NPKTMEPEEINMIQSFLRFNFDEISSFKASLNILRKVLIFINLKSDDFEDAYKGLNEM
GRKLINSEASSAFKGIITNHNMFSELSLAALLENVRFLEQCTIQLSSFVQIILFEKIP
NWWKHYGEFLALHKSYRKAFPNMVKPKSASDTSSRAPLGGFIETKREQSEQRLAVQIK
ASSKMLKELGSEIFVAHERLAEELSNYMEFRKACLDQRSLVAFATTNISVLQECV"
gene 267174..267800
/gene="YPT7"
/locus_tag="YML001W"
/gene_synonym="AST4; VAM4"
/db_xref="GeneID:855012"
mRNA 267174..267800
/gene="YPT7"
/locus_tag="YML001W"
/gene_synonym="AST4; VAM4"
/product="Ypt7p"
/transcript_id="NM_001182356.1"
/db_xref="GI:296147118"
/db_xref="GeneID:855012"
CDS 267174..267800
/gene="YPT7"
/locus_tag="YML001W"
/gene_synonym="AST4; VAM4"
/note="Rab family GTPase; GTP-binding protein of the rab
family; required for homotypic fusion event in vacuole
inheritance, for endosome-endosome fusion; interacts with
the cargo selection/retromer complex for retrograde
sorting; similar to mammalian Rab7"
/codon_start=1
/product="Ypt7p"
/protein_id="NP_013713.1"
/db_xref="GI:6323642"
/db_xref="SGD:S000004460"
/db_xref="GeneID:855012"
/translation="MSSRKKNILKVIILGDSGVGKTSLMHRYVNDKYSQQYKATIGAD
FLTKEVTVDGDKVATMQVWDTAGQERFQSLGVAFYRGADCCVLVYDVTNASSFENIKS
WRDEFLVHANVNSPETFPFVILGNKIDAEESKKIVSEKSAQELAKSLGDIPLFLTSAK
NAINVDTAFEEIARSALQQNQADTEAFEDDYNDAINIRLDGENNSCSC"
centromere 268031..268149
/note="CEN13; Chromosome XIII centromere"
/db_xref="SGD:S000006474"
centromere 268031..268040
/note="CEN13_CDEI of CEN13"
centromere 268041..268124
/note="CEN13_CDEII of CEN13"
centromere 268125..268149
/note="CEN13_CDEIII of CEN13"
gene complement(269019..271136)
/gene="CDC5"
/locus_tag="YMR001C"
/gene_synonym="MSD2; PKX2"
/db_xref="GeneID:855013"
mRNA complement(269019..271136)
/gene="CDC5"
/locus_tag="YMR001C"
/gene_synonym="MSD2; PKX2"
/product="Cdc5p"
/transcript_id="NM_001182497.1"
/db_xref="GI:296147119"
/db_xref="GeneID:855013"
CDS complement(269019..271136)
/gene="CDC5"
/locus_tag="YMR001C"
/gene_synonym="MSD2; PKX2"
/EC_number="2.7.11.21"
/note="Polo-like kinase with multiple functions in mitosis
and cytokinesis through substrate phosphorylation, also
functions in adaptation to DNA damage during meiosis; has
similarity to Xenopus Plx1 and S. pombe Plo1p; possible
Cdc28p substrate"
/codon_start=1
/product="polo kinase CDC5"
/protein_id="NP_013714.1"
/db_xref="GI:6323643"
/db_xref="SGD:S000004603"
/db_xref="GeneID:855013"
/translation="MSLGPLKAINDKQLNTRSKLVHTPIKGNTADLVGKENHFKQTKR
LDPNNDHHHQPAQKKKREKLSALCKTPPSLIKTRGKDYHRGHFLGEGGFARCFQIKDD
SGEIFAAKTVAKASIKSEKTRKKLLSEIQIHKSMSHPNIVQFIDCFEDDSNVYILLEI
CPNGSLMELLKRRKVLTEPEVRFFTTQICGAIKYMHSRRVIHRDLKLGNIFFDSNYNL
KIGDFGLAAVLANESERKYTICGTPNYIAPEVLMGKHSGHSFEVDIWSLGVMLYALLI
GKPPFQARDVNTIYERIKCRDFSFPRDKPISDEGKILIRDILSLDPIERPSLTEIMDY
VWFRGTFPPSIPSTVMSEAPNFEDIPEEQSLVNFKDCMEKSLLLESMSSDKIQRQKRD
YISSIKSSIDKLEEYHQNRPFLPHSLSPGGTKQKYKEVVDIEAQRRLNDLAREARIRR
AQQAVLRKELIATSTNVIKSEISLRILASECHLTLNGIVEAEAQYKMGGLPKSRLPKI
KHPMIVTKWVDYSNKHGFSYQLSTEDIGVLFNNGTTVLRLADAEEFWYISYDDREGWV
ASHYLLSEKPRELSRHLEVVDFFAKYMKANLSRVSTFGREEYHKDDVFLRRYTRYKPF
VMFELSDGTFQFNFKDHHKMAISDGGKLVTYISPSHESTTYPLVEVLKYGEIPGYPES
NFREKLTLIKEGLKQKSTIVTVD"
gene complement(271347..271577)
/locus_tag="YMR001C-A"
/db_xref="GeneID:1466498"
mRNA complement(271347..271577)
/locus_tag="YMR001C-A"
/product="hypothetical protein"
/transcript_id="NM_001184613.1"
/db_xref="GI:296147120"
/db_xref="GeneID:1466498"
CDS complement(271347..271577)
/locus_tag="YMR001C-A"
/codon_start=1
/product="hypothetical protein"
/protein_id="NP_878140.1"
/db_xref="GI:33438852"
/db_xref="SGD:S000028691"
/db_xref="GeneID:1466498"
/translation="MIFECTSFETRHILNSYSCATQLSYNTYRITEKVNPIQAAVSKN
NKPFVSNSDSAFFPIFSSFNFVAYTTLTFKKT"
gene 272193..272663
/gene="MIC17"
/locus_tag="YMR002W"
/db_xref="GeneID:855014"
mRNA 272193..272663
/gene="MIC17"
/locus_tag="YMR002W"
/product="Mic17p"
/transcript_id="NM_001182498.1"
/db_xref="GI:296147121"
/db_xref="GeneID:855014"
CDS 272193..272663
/gene="MIC17"
/locus_tag="YMR002W"
/note="Mitochondrial intermembrane space protein; required
for normal oxygen consumption; contains twin
cysteine-x9-cysteine motifs; protein abundance increases
in response to DNA replication stress"
/codon_start=1
/product="Mic17p"
/protein_id="NP_013715.1"
/db_xref="GI:6323644"
/db_xref="SGD:S000004604"
/db_xref="GeneID:855014"
/translation="MARSRGSSRPISRSRPTQTRSASTMAAPVHPQQQQQPNAYSHPP
AAGAQTRQPGMFAQMASTAAGVAVGSTIGHTLGAGITGMFSGSGSDSAPVEQQQQNMA
NTSGQTQTDQQLGRTCEIDARNFTRCLDENNGNFQICDYYLQQLKACQEAARQY"
gene 273118..273714
/gene="AIM34"
/locus_tag="YMR003W"
/db_xref="GeneID:855015"
mRNA 273118..273714
/gene="AIM34"
/locus_tag="YMR003W"
/product="Aim34p"
/transcript_id="NM_001182499.1"
/db_xref="GI:296147122"
/db_xref="GeneID:855015"
CDS 273118..273714
/gene="AIM34"
/locus_tag="YMR003W"
/note="hypothetical protein; GFP-fusion protein localizes
to the mitochondria; null mutant is viable and displays
reduced frequency of mitochondrial genome loss"
/codon_start=1
/product="Aim34p"
/protein_id="NP_013716.1"
/db_xref="GI:6323645"
/db_xref="SGD:S000004605"
/db_xref="GeneID:855015"
/translation="MSISLLGRIVSQQFSGIRAAEPGRSLYLPFTLLLKQPGAYKVSL
HRYVHSTQTKSHLSFLMNNNDITPFQKFTVKVLKEQCKSRGLKLSGRKSDLLQRLITH
DSCSNKKSSVKINEPKKKRILINDPIKITKKLVSDKTFRTIEKNISSLQNTPVIETPC
DVHSHLQPRDRIFLLGFFMLSCLWWNLEPQESKPTIDH"
gene 274017..275552
/gene="MVP1"
/locus_tag="YMR004W"
/db_xref="GeneID:855016"
mRNA 274017..275552
/gene="MVP1"
/locus_tag="YMR004W"
/product="Mvp1p"
/transcript_id="NM_001182500.1"
/db_xref="GI:296147123"
/db_xref="GeneID:855016"
CDS 274017..275552
/gene="MVP1"
/locus_tag="YMR004W"
/note="Protein required for sorting proteins to the
vacuole; Mvp1p and Vps1p act in concert to promote
membrane traffic to the vacuole; participates in
transcription initiation and/or early elongation of
specific genes; interacts with 'foot domain' of RNA
polymerase II; deletion results in abnormal CTD-Ser5
phosphorylation of RNA polymerase II at specific promoter
regions; protein abundance increases in response to DNA
replication stress"
/codon_start=1
/product="Mvp1p"
/protein_id="NP_013717.1"
/db_xref="GI:6323646"
/db_xref="SGD:S000004606"
/db_xref="GeneID:855016"
/translation="MDNYEGSDPWNTSSNAWTKDDDHVVSTTNSEPSLNGISGEFNTL
NFSTPLDTNEEDTGFLPTNDVLEESIWDDSRNPLGATGMSQTPNIAANETVIDKNDAR
DQNIEESEADLLDWTNNVRKTYRPLDADIIIIEEIPEREGLLFKHANYLVKHLIALPS
TSPSEERTVVRRYSDFLWLREILLKRYPFRMIPELPPKRIGSQNADQLFLKKRRIGLS
RFINLVMKHPKLSNDDLVLTFLTVRTDLTSWRKQATYDTSNEFADKKISQEFMKMWKK
EFAEQWNQAASCIDTSMELWYRITLLLERHEKRIMQMVHERNFFETLVDNFSEVTPKL
YPVQQNDTILDINNNLSIIKKHLETTSSICKQETEEISGTLSPKFKIFTDILLSLRSL
FERYKIMAANNVVELQRHVELNKEKLESMKGKPDVSGAEYDRIKKIIQKDRRSIIEQS
NRAWLIRQCILEEFTIFQETQFLITRAFQDWAKLNSNHAGLKLNEWEKLVTSIMDMPI
SRE"
gene 276045..277211
/gene="TAF4"
/locus_tag="YMR005W"
/gene_synonym="MPT1; TAF48; TSG2"
/db_xref="GeneID:855017"
mRNA 276045..277211
/gene="TAF4"
/locus_tag="YMR005W"
/gene_synonym="MPT1; TAF48; TSG2"
/product="Taf4p"
/transcript_id="NM_001182501.1"
/db_xref="GI:296147124"
/db_xref="GeneID:855017"
CDS 276045..277211
/gene="TAF4"
/locus_tag="YMR005W"
/gene_synonym="MPT1; TAF48; TSG2"
/note="TFIID subunit (48 kDa), involved in RNA polymerase
II transcription initiation; potential Cdc28p substrate"
/codon_start=1
/product="Taf4p"
/protein_id="NP_013718.1"
/db_xref="GI:6323647"
/db_xref="SGD:S000004607"
/db_xref="GeneID:855017"
/translation="MANSPKKPSDGTGVSASDTPKYQHTVPETKPAFNLSPGKASELS
HSLPSPSQIKSTAHVSSTHNDAAGNTDDSVLPKNVSPTTNLRVESNGDTNNMFSSPAG
LALPKKDDKKKNKGTSKADSKDGKASNSSGQNAQQQSDPNKMQDVLFSAGIDVREEEA
LLNSSINASKSQVQTNNVKIPNHLPFLHPEQVSNYMRKVGKEQNFNLTPTKNPEILDM
MSSACENYMRDILTNAIVISRHRRKAVKINSGRRSEVSAALRAIALIQKKEEERRVKK
RIALGLEKEDYENKIDSEETLHRASNVTAGLRAGSKKQYGWLTSSVNKPTSLGAKSSG
KVASDITARGESGLKFREAREEPGIVMRDLLFALENRRNSVQTIISKGYAKIRD"
gene complement(277561..279681)
/gene="PLB2"
/locus_tag="YMR006C"
/db_xref="GeneID:855018"
mRNA complement(277561..279681)
/gene="PLB2"
/locus_tag="YMR006C"
/product="Plb2p"
/transcript_id="NM_001182502.1"
/db_xref="GI:296147125"
/db_xref="GeneID:855018"
CDS complement(277561..279681)
/gene="PLB2"
/locus_tag="YMR006C"
/EC_number="3.1.1.5"
/note="Phospholipase B (lysophospholipase) involved in
phospholipid metabolism; displays transacylase activity in
vitro; overproduction confers resistance to
lysophosphatidylcholine"
/codon_start=1
/product="Plb2p"
/protein_id="NP_013719.1"
/db_xref="GI:6323648"
/db_xref="SGD:S000004608"
/db_xref="GeneID:855018"
/translation="MQLRNILQASSLISGLSLAADSSSTTGDGYAPSIIPCPSDDTSL
VRNASGLSTAETDWLKKRDAYTKEALHSFLSRATSNFSDTSLLSTLFSSNSSNVPKIG
IACSGGGYRAMLGGAGMIAAMDNRTDGANEHGLGGLLQSSTYLSGLSGGNWLTGTLAW
NNWTSVQEIVDHMSESDSIWNITKSIVNPGGSNLTYTIERWESIVQEVQAKSDAGFNI
SLSDLWARALSYNFFPSLPDAGSALTWSSLRDVDVFKNGEMPLPITVADGRYPGTTVI
NLNATLFEFTPFEMGSWDPSLNAFTDVKYLGTNVTNGKPVNKDQCVSGYDNAGFVIAT
SASLFNEFSLEASTSTYYKMINSFANKYVNNLSQDDDDIAIYAANPFKDTEFVDRNYT
SSIVDADDLFLVDGGEDGQNLPLVPLIKKERDLDVVFALDISDNTDESWPSGVCMTNT
YERQYSKQGKGMAFPYVPDVNTFLNLGLTNKPTFFGCDAKNLTDLEYIPPLVVYIPNT
KHSFNGNQSTLKMNYNVTERLGMIRNGFEAATMGNFTDDSNFLGCIGCAIIRRKQESL
NATLPPECTKCFADYCWNGTLSTSANPELSGNSTYQSGAIASAISEATDGIPITALLG
SSTSGNTTSNSTTSTSSNVTSNSNSSSNTTLNSNSSSSSISSSTARSSSSTANKANAA
AISYANTNTLMSLLGAITALFGLI"
gene complement(280590..282584)
/gene="PLB1"
/locus_tag="YMR008C"
/db_xref="GeneID:855020"
mRNA complement(280590..282584)
/gene="PLB1"
/locus_tag="YMR008C"
/product="Plb1p"
/transcript_id="NM_001182504.1"
/db_xref="GI:296147126"
/db_xref="GeneID:855020"
CDS complement(280590..282584)
/gene="PLB1"
/locus_tag="YMR008C"
/EC_number="3.1.1.5"
/note="Phospholipase B (lysophospholipase) involved in
lipid metabolism, required for deacylation of
phosphatidylcholine and phosphatidylethanolamine but not
phosphatidylinositol"
/codon_start=1
/product="Plb1p"
/protein_id="NP_013721.1"
/db_xref="GI:6323650"
/db_xref="SGD:S000004610"
/db_xref="GeneID:855020"
/translation="MKLQSLLVSAAVLTSLTENVNAWSPNNSYVPANVTCDDDINLVR
EASGLSDNETEWLKKRDAYTKEALHSFLNRATSNFSDTSLLSTLFGSNSSNMPKIAVA
CSGGGYRAMLSGAGMLAAMDNRTDGANEHGLGGLLQGATYLAGLSGGNWLTSTLAWNN
WTSVQAIVDNTTESNSIWDISHSILTPDGINIFKTGSRWDDISDDVQDKKDAGFNISL
ADVWGRALAYNFWPSLHRGGVGYTWSTLREADVFKNGEMPFPITVADGRYPGTTVINL
NATLFEFNPFEMGSWDPTLNAFTDVKYLGTNVTNGKPVNKGQCIAGFDNTGFITATSS
TLFNQFLLRLNSTDLPSFIANLATDFLEDLSDNSDDIAIYAPNPFKEANFLQKNATSS
IIESEYLFLVDGGEDNQNIPLVPLLQKERELDVIFALDNSADTDDYWPDGASLVNTYQ
RQFGSQGLNLSFPYVPDVNTFVNLGLNKKPTFFGCDARNLTDLEYIPPLIVYIPNSRH
SFNGNQSTFKMSYSDSERLGMIKNGFEAATMGNFTDDSDFLGCVGCAIIRRKQQNLNA
TLPSECSQCFTNYCWNGTIDSRSVSGVGNDDYSSSASLSASAAAASASASASASASAS
ASGSSTHKKNAGNALVNYSNLNTNTFIGVLSVISAVFGLI"
gene 284102..284641
/gene="ADI1"
/locus_tag="YMR009W"
/db_xref="GeneID:855021"
mRNA 284102..284641
/gene="ADI1"
/locus_tag="YMR009W"
/product="acireductone dioxygenase (Ni2+-requiring)"
/transcript_id="NM_001182505.1"
/db_xref="GI:296147127"
/db_xref="GeneID:855021"
CDS 284102..284641
/gene="ADI1"
/locus_tag="YMR009W"
/EC_number="1.13.-.-"
/note="Acireductone dioxygenease involved in the
methionine salvage pathway; ortholog of human MTCBP-1;
transcribed as polycistronic mRNA with YMR010W and
regulated post-transcriptionally by RNase III (Rnt1p)
cleavage; ADI1 mRNA is induced in heat shock conditions"
/codon_start=1
/product="acireductone dioxygenase (Ni2+-requiring)"
/protein_id="NP_013722.1"
/db_xref="GI:6323651"
/db_xref="SGD:S000004611"
/db_xref="GeneID:855021"
/translation="MVKVYIHDNKVDSDYRAPHNSGTELSLDELAKLGVIYKYCANEE
EVNEIARQREYKNRDVVNICEGSFKSEAEFNEKLATFYQEHLHEDEEIRYCLEGAGYF
DVRDASTPENWIRCLVESGDLLILPPGIYHRFTLTTSNHIKALRLFKDEPKWQAINRS
NQADSLPVRKDYIALINQY"
gene 285100..286317
/locus_tag="YMR010W"
/db_xref="GeneID:855022"
mRNA 285100..286317
/locus_tag="YMR010W"
/product="hypothetical protein"
/transcript_id="NM_001182506.1"
/db_xref="GI:296147128"
/db_xref="GeneID:855022"
CDS 285100..286317
/locus_tag="YMR010W"
/note="hypothetical protein; green fluorescent protein
(GFP)-fusion protein localizes to the cytoplasm; YMR010W
is not an essential gene; YMR010W mRNA is transcribed with
ADI1"
/codon_start=1
/product="hypothetical protein"
/protein_id="NP_013723.1"
/db_xref="GI:6323652"
/db_xref="SGD:S000004612"
/db_xref="GeneID:855022"
/translation="MSTTGPLDATLIRDVAVATATKASYDMSDTLYSYLPKVDQFYIP
EWLTMQFIANNLISFTPLFSYGTTIISIEKCKTALGFSIDICATMLIASILRISYYLI
TPYEITLLRQSLVMIFIQLILLRTSLKYRPDEYKYQNLTDVESLSHLIHDIWFEFFSC
INRPKFLSEDWKNLIKSLSFTNLLKFSFKIFLAFFYKILKFFDPNFKRIGAFWQWDDD
KNFWRFLALFATVQILVTFFISNILNWDSLAQGLGSIIGSLGLLVESLLPLPQIAILY
KLKSVQGFKLILLVSWLCGDTLKITYLIFGAKNISALFVIFALFQMSLDFYIGGQYIY
YRYYYPKLRHQHHPNDSNSPSDEDESEMYELDLFNTLQKDVEKALKQDSNDTSDSPQD
DQVGKSQAQAVTL"
rep_origin 286784..287068
/note="ARS1310;
Autonomously Replicating Sequence"
/db_xref="SGD:S000118370"
gene 288079..289704
/gene="HXT2"
/locus_tag="YMR011W"
/db_xref="GeneID:855023"
mRNA 288079..289704
/gene="HXT2"
/locus_tag="YMR011W"
/product="Hxt2p"
/transcript_id="NM_001182507.1"
/db_xref="GI:296147129"
/db_xref="GeneID:855023"
CDS 288079..289704
/gene="HXT2"
/locus_tag="YMR011W"
/note="High-affinity glucose transporter of the major
facilitator superfamily, expression is induced by low
levels of glucose and repressed by high levels of glucose"
/codon_start=1
/product="Hxt2p"
/protein_id="NP_013724.1"
/db_xref="GI:6323653"
/db_xref="SGD:S000004613"
/db_xref="GeneID:855023"
/translation="MSEFATSRVESGSQQTSIHSTPIVQKLETDESPIQTKSEYTNAE
LPAKPIAAYWTVICLCLMIAFGGFVFGWDTGTISGFVNQTDFKRRFGQMKSDGTYYLS
DVRTGLIVGIFNIGCAFGGLTLGRLGDMYGRRIGLMCVVLVYIVGIVIQIASSDKWYQ
YFIGRIISGMGVGGIAVLSPTLISETAPKHIRGTCVSFYQLMITLGIFLGYCTNYGTK
DYSNSVQWRVPLGLNFAFAIFMIAGMLMVPESPRFLVEKGRYEDAKRSLAKSNKVTIE
DPSIVAEMDTIMANVETERLAGNASWGELFSNKGAILPRVIMGIMIQSLQQLTGNNYF
FYYGTTIFNAVGMKDSFQTSIVLGIVNFASTFVALYTVDKFGRRKCLLGGSASMAICF
VIFSTVGVTSLYPNGKDQPSSKAAGNVMIVFTCLFIFFFAISWAPIAYVIVAESYPLR
VKNRAMAIAVGANWIWGFLIGFFTPFITSAIGFSYGYVFMGCLVFSFFYVFFFVCETK
GLTLEEVNEMYVEGVKPWKSGSWISKEKRVSEE"
LTR complement(290049..290224)
/note="Ty4 LTR"
/db_xref="SGD:S000007117"
gene 290801..290872
/locus_tag="tE(UUC)M"
/db_xref="GeneID:855024"
tRNA 290801..290872
/locus_tag="tE(UUC)M"
/product="tRNA-Glu"
/note="Glutamate tRNA (tRNA-Glu), predicted by tRNAscan-SE
analysis; thiolation of uridine at wobble position (34)
requires Ncs6p"
/db_xref="SGD:S000006560"
/db_xref="GeneID:855024"
gene 291134..294967
/gene="CLU1"
/locus_tag="YMR012W"
/gene_synonym="TIF31"
/db_xref="GeneID:855025"
mRNA 291134..294967
/gene="CLU1"
/locus_tag="YMR012W"
/gene_synonym="TIF31"
/product="Clu1p"
/transcript_id="NM_001182508.1"
/db_xref="GI:296147130"
/db_xref="GeneID:855025"
CDS 291134..294967
/gene="CLU1"
/locus_tag="YMR012W"
/gene_synonym="TIF31"
/note="eIF3 component of unknown function; deletion causes
defects in mitochondrial organization but not in growth or
translation initiation, can rescue cytokinesis and
mitochondrial organization defects of the Dictyostelium
cluA- mutant"
/codon_start=1
/product="Clu1p"
/protein_id="NP_013725.1"
/db_xref="GI:6323654"
/db_xref="SGD:S000004614"
/db_xref="GeneID:855025"
/translation="MSEKKEEVKNATVKVTVKLPKEDNHSHNTKHLKKTQSSKNNDIS
FEIGKESKIQTVLDVLAMIPSSKYLTNVGLKTIEGDSQLSDEMSIKEIVGEKSELKLQ
LILKPYSAREALKHVITVRDFIGFAQETSDGLSEFAISTGSSFSSLPLGPIKERSKQE
EKDEKSDPEEKKNTFKDVTDEEKLKFNEMVHEVFSSFKNSSINKLLTSESNIITPCVR
SLSFAPYNPVPPFYRSKGHLFYLQIVTLEGESFYITAIPSGFYVNKSNSTKFDPSPKE
NTDENAHSSLIYYSLFDLIASRSKKFISHVQAFEKKLSALDSTSYVRPSNTFLHKPWF
VSSLPPNNPDYLRLQTAALDTTPERNFNDEFQAIKDLTTSTLQDRIEMERLFSKVVHE
FSVTAASGAMSIFYSDFVAMNPESPTRDQIFLKDNIFYSYVSDVSGNYEGKGGDEAAI
AASNQDLKTINILNRLHMHEVRYLLTTVVEFAGRRILAQTPVPGLLATMGNKIVKDAN
TGEEVTEDFVNDINVKYGLDEGLGKIVYDADFDSVLEKKFVKAFHLKKHKVNGTELAF
SSQSKGIVGFDKRRYILDLANTYPLDINFARQNFDNIEETGNRYPHRQTLLRPELVEK
WWNNKVEKEGVEFEKAYEENLFSYNPDAYQVEGIEDANVDEMSNYLQKEVIPSVIQDY
LSGNLSTPYNGEHLADTLHKNGINMRYLGKIIELSQKELDSQIVHYEQNLKAVEQDNK
EYEDWEKSYLQKIENMIKERQAKINKLVQEGKEVPKELTEDLKLNDEEIKKPTDGKPV
VVAYDELVPLIKISELEIVSRSLKHVLKDLSKDVPVFLVPSLVAYVFNMLVGINYNAD
PKPEPVDEFYPVNKCSFAKLTRSELLEAVSKQAFLRFRHQLPSNWIEAYMENPFTLIR
SVSYKFGIQLLNKEYFFTREQLESYKQSLDKKIRNKFVEPPTTFSLSDLTIIPRVKFS
EYTSSVSEEFWAQGASMINEDKQSALTLLAQSITVLEDVNNILHPAVAEKYLSLSAIY
NKLALYPEAIAFCRKACTIYERVSGIDSFEMMRALTNLAILEFSNESPYNATVVYNRL
AEILKVYELPKIHHPAPTSIFNHLEQLALGVQDTKLAIEVLGQLSSYVVELEGKDSLA
YGYTESRLGNLFAALKDFHRALEHITVTQGIFTKQLGMNHTHSAQSRQWVNGLSSLIM
DLKQKKQLAQDQMSTTGSNSAGHKKTNHRQKKDDVKPELANKSVDELLTFIEGDSSNS
KSKNKTNNKKKHGKK"
gene complement(295179..296738)
/gene="SEC59"
/locus_tag="YMR013C"
/db_xref="GeneID:855026"
mRNA complement(295179..296738)
/gene="SEC59"
/locus_tag="YMR013C"
/product="Sec59p"
/transcript_id="NM_001182509.1"
/db_xref="GI:296147131"
/db_xref="GeneID:855026"
CDS complement(295179..296738)
/gene="SEC59"
/locus_tag="YMR013C"
/EC_number="2.7.1.108"
/note="Dolichol kinase, catalyzes the terminal step in
dolichyl monophosphate (Dol-P) biosynthesis; required for
viability and for normal rates of lipid intermediate
synthesis and protein N-glycosylation"
/codon_start=1
/product="Sec59p"
/protein_id="NP_013726.1"
/db_xref="GI:6323655"
/db_xref="SGD:S000004615"
/db_xref="GeneID:855026"
/translation="MVAIIPHASFTTIKLTQKTEGSQMPTEEICKINMRTRKFDVGGN
SRDFECFYSNFVQTVILLGTFFYCVERLQPWSIVTADISYKQIFVNVFVVCLIMVGLI
FTKYWQHGYKSLPKFDTIYSLYLPFMVSLLFDTSSTVINTILILSVLNSYRWRTQLVV
IILQLCLIFFNFEAGDRLKNIISIVINSLLSLILKYIGQLKSLDNIDSNLFSILLTNI
LYVSEAGTVHFRILKGIILALTTIISINYVLKKVMHFKPFMLSISFAIGLPLFANTFI
HLEDGENPLLWLVKYILESTIRQKILFAWSSILILSIPSILIEKDSLSLNTSRKLWHF
IIFLLIIPSFQMDSNFVKIALSGTIPVFLSIEYIRFQNLPPLGSAIELQLRRFADDRD
HSGPLIISYLYLLFGISTPLLMNNSPMGLIGLGIGDSLASIIGKRYGRIRWKGTQKTL
EGTLAFIVTSFIVCLVLLRFDKAAIFNHLTTLQLLTLCTLSGVLEGNSVLNDNILIPA
FMMICEKLITL"
gene 297278..297364
/locus_tag="snR78"
/db_xref="GeneID:9164958"
ncRNA 297278..297364
/locus_tag="snR78"
/ncRNA_class="snoRNA"
/product="SNR78"
/note="C/D box small nucleolar RNA (snoRNA), guides
2'-O-methylation of large subunit (LSU) rRNA at position
U2421"
/db_xref="SGD:S000007312"
/db_xref="GeneID:9164958"
gene 297506..297593
/locus_tag="snR77"
/db_xref="GeneID:9164954"
ncRNA 297506..297593
/locus_tag="snR77"
/ncRNA_class="snoRNA"
/product="SNR77"
/note="C/D box small nucleolar RNA (snoRNA), guides
2'-O-methylation of small subunit (SSU) rRNA at position
U578"
/db_xref="SGD:S000007311"
/db_xref="GeneID:9164954"
gene 297725..297833
/locus_tag="snR76"
/db_xref="GeneID:9164962"
ncRNA 297725..297833
/locus_tag="snR76"
/ncRNA_class="snoRNA"
/product="SNR76"
/note="C/D box small nucleolar RNA (snoRNA), guides
2'-O-methylation of large subunit (LSU) rRNA at position
C2197"
/db_xref="SGD:S000007310"
/db_xref="GeneID:9164962"
gene 297918..298006
/locus_tag="snR75"
/db_xref="GeneID:9164956"
ncRNA 297918..298006
/locus_tag="snR75"
/ncRNA_class="snoRNA"
/product="SNR75"
/note="C/D box small nucleolar RNA (snoRNA), guides
2'-O-methylation of large subunit (LSU) rRNA at position
G2288"
/db_xref="SGD:S000007309"
/db_xref="GeneID:9164956"
gene 298138..298225
/locus_tag="snR74"
/db_xref="GeneID:9164964"
ncRNA 298138..298225
/locus_tag="snR74"
/ncRNA_class="snoRNA"
/product="SNR74"
/note="C/D box small nucleolar RNA (snoRNA), guides
2'-O-methylation of small subunit (SSU) rRNA at position
A28"
/db_xref="SGD:S000007308"
/db_xref="GeneID:9164964"
gene 298307..298412
/locus_tag="snR73"
/db_xref="GeneID:9164963"
ncRNA 298307..298412
/locus_tag="snR73"
/ncRNA_class="snoRNA"
/product="SNR73"
/note="C/D box small nucleolar RNA (snoRNA), guides
2'-O-methylation of large subunit (LSU) rRNA at position
C2959"
/db_xref="SGD:S000007307"
/db_xref="GeneID:9164963"
gene 298554..298651
/locus_tag="snR72"
/db_xref="GeneID:9164953"
ncRNA 298554..298651
/locus_tag="snR72"
/ncRNA_class="snoRNA"
/product="SNR72"
/note="C/D box small nucleolar RNA (snoRNA), guides
2'-O-methylation of large subunit (LSU) rRNA at position
A876"
/db_xref="SGD:S000007306"
/db_xref="GeneID:9164953"
gene 298868..300427
/gene="BUD22"
/locus_tag="YMR014W"
/db_xref="GeneID:855028"
mRNA 298868..300427
/gene="BUD22"
/locus_tag="YMR014W"
/product="Bud22p"
/transcript_id="NM_001182510.1"
/db_xref="GI:296147132"
/db_xref="GeneID:855028"
CDS 298868..300427
/gene="BUD22"
/locus_tag="YMR014W"
/note="Protein required for 18S rRNA maturation and small
ribosomal subunit biogenesis; cosediments with
pre-ribosomal particles; mutation decreases efficiency of
+1 Ty1 frameshifting and transposition, and affects
budding pattern"
/codon_start=1
/product="Bud22p"
/protein_id="NP_013727.1"
/db_xref="GI:6323656"
/db_xref="SGD:S000004616"
/db_xref="GeneID:855028"
/translation="MPSESSVSIYKLDQLEYQYHYLTKSLQKFEPRYPKTAKLYNCIG
KKNKKKIEKLLNSLELKTLDKELDESYSKLLNNKIHYYETHLSKCIKEQIQKISKKNS
SKVKDAQKNKSPSIDIEKMLATQLSLDDLALFMTRFRLIKILHQRIKQKSKKIEGDTN
NKTWLNNNDYSGYINDKTSKWNPSNIWNEVITKLPSCEKLNALIGQSKIVQNLTESFD
LSICLIFGFDVSAMKAKKYGAREKTANANQTHSNIDYDTDDGNEKNAIDSKSNAIGAQ
TQSNKETTSDNEDLLIKEYEGMLGSSGDEGEGGGYLNPNINYNEVTDEEPSEASSDED
DSDERFSDSEENEPRRKKPKLHNLPELMAGYYSGNDTEEESDEDNKNVKGKKKKRDTA
EDRTAREQMSNEPKRKNRRGQRARRKIWEKKYGSQAKHVQRELEKEMEDRKQRQIEYE
ARVAKREAKAASLEASRSREREDRRTETNNKKEKESASTGEEHPSWIAKRLAEEKLQK
AKFEGKKIKFD"
gene complement(300869..302485)
/gene="ERG5"
/locus_tag="YMR015C"
/gene_synonym="CYP61"
/db_xref="GeneID:855029"
mRNA complement(300869..302485)
/gene="ERG5"
/locus_tag="YMR015C"
/gene_synonym="CYP61"
/product="C-22 sterol desaturase"
/transcript_id="NM_001182511.1"
/db_xref="GI:296147133"
/db_xref="GeneID:855029"
CDS complement(300869..302485)
/gene="ERG5"
/locus_tag="YMR015C"
/gene_synonym="CYP61"
/EC_number="1.14.14.-"
/note="C-22 sterol desaturase, a cytochrome P450 enzyme
that catalyzes the formation of the C-22(23) double bond
in the sterol side chain in ergosterol biosynthesis; may
be a target of azole antifungal drugs"
/codon_start=1
/product="C-22 sterol desaturase"
/protein_id="NP_013728.1"
/db_xref="GI:6323657"
/db_xref="SGD:S000004617"
/db_xref="GeneID:855029"
/translation="MSSVAENIIQHATHNSTLHQLAKDQPSVGVTTAFSILDTLKSMS
YLKIFATLICILLVWDQVAYQIKKGSIAGPKFKFWPIIGPFLESLDPKFEEYKAKWAS
GPLSCVSIFHKFVVIASTRDLARKILQSSKFVKPCVVDVAVKILRPCNWVFLDGKAHT
DYRKSLNGLFTKQALAQYLPSLEQIMDKYMDKFVRLSKENNYEPQVFFHEMREILCAL
SLNSFCGNYITEDQVRKIADDYYLVTAALELVNFPIIIPYTKTWYGKKTADMAMKIFE
NCAQMAKDHIAAGGKPVCVMDAWCKLMHDAKNSNDDDSRIYHREFTNKEISEAVFTFL
FASQDASSSLACWLFQIVADRPDVLAKIREEQLAVRNNDMSTELNLDLIEKMKYTNMV
IKETLRYRPPVLMVPYVVKKNFPVSPNYTAPKGAMLIPTLYPALHDPEVYENPDEFIP
ERWVEGSKASEAKKNWLVFGCGPHVCLGQTYVMITFAALLGKFALYTDFHHTVTPLSE
KIKVFATIFPKDDLLLTFKKRDPITGEVFE"
gene complement(303236..305593)
/gene="SOK2"
/locus_tag="YMR016C"
/db_xref="GeneID:855030"
mRNA complement(303236..305593)
/gene="SOK2"
/locus_tag="YMR016C"
/product="Sok2p"
/transcript_id="NM_001182512.1"
/db_xref="GI:296147134"
/db_xref="GeneID:855030"
CDS complement(303236..305593)
/gene="SOK2"
/locus_tag="YMR016C"
/note="Nuclear protein that negatively regulates
pseudohyphal differentiation; plays a regulatory role in
the cyclic AMP (cAMP)-dependent protein kinase (PKA)
signal transduction pathway; SOK2 has a paralog, PHD1,
that arose from the whole genome duplication"
/codon_start=1
/product="Sok2p"
/protein_id="NP_013729.1"
/db_xref="GI:6323658"
/db_xref="SGD:S000004618"
/db_xref="GeneID:855030"
/translation="MPIGNPINTNDIKSNRMRQESNMSAVSNSESTIGQSTQQQQQQQ
QYLGQSVQPLMPVSYQYVVPEQWPYPQYYQQPQSQSQQQLQSQPQMYQVQESFQSSGS
DSNASNPPSTSVGVPSNATATALPNGSAITTKKSNNSTNISNNVPYYYYFPQMQAQQS
MAYSYPQAYYYYPANGDGTTNGATPSVTSNQVQNPNLEKTYSTFEQQQQHQQQQQLQA
QTYPAQPPKIGNAFSKFSKSGPPSDSSSGSMSPNSNRTSRNSNSISSLAQQPPMSNYP
QPSTYQYPGFHKTSSIPNSHSPIPPRSLTTPTQGPTSQNGPLSYNLPQVGLLPPQQQQ
QVSPLYDGNSITPPVKPSTDQETYLTANRHGVSDQQYDSMAKTMNSFQTTTIRHPMPL
IATTNATGSNTSGTSASIIRPRVTTTMWEDEKTLCYQVEANGISVVRRADNDMVNGTK
LLNVTKMTRGRRDGILKAEKIRHVVKIGSMHLKGVWIPFERALAIAQREKIADYLYPL
FIRDIQSVLKQNNPSNDSSSSSSSTGIKSISPRTYYQPINNYQNPNGPSNISAAQLTY
SSMNLNNKIIPNNSIPAVSTIAAGEKPLKKCTMPNSNQLEGHTITNLQTLSATMPMKQ
QLMGNIASPLSYPRNATMNSASTLGITPADSKPLTPSPTTTNTNQSSESNVGSIHTGI
TLPRVESESASHSKWSKEADSGNTVPDNQTLKEPRSSQLPISALTSTDTDKIKTSTSD
EATQPNEPSEAEPVKESESSKSQVDGAGDVSNEEIAADDTKKQEK"
gene 307489..308682
/gene="SPO20"
/locus_tag="YMR017W"
/gene_synonym="DBI9"
/db_xref="GeneID:855031"
mRNA 307489..308682
/gene="SPO20"
/locus_tag="YMR017W"
/gene_synonym="DBI9"
/product="Spo20p"
/transcript_id="NM_001182513.1"
/db_xref="GI:296147135"
/db_xref="GeneID:855031"
CDS 307489..308682
/gene="SPO20"
/locus_tag="YMR017W"
/gene_synonym="DBI9"
/note="Meiosis-specific subunit of the t-SNARE complex,
required for prospore membrane formation during
sporulation; similar to but not functionally redundant
with Sec9p; SNAP-25 homolog"
/codon_start=1
/product="Spo20p"
/protein_id="NP_013730.1"
/db_xref="GI:6323659"
/db_xref="SGD:S000004619"
/db_xref="GeneID:855031"
/translation="MGFRKILASKSHHSRHHNQHHKNLKLQNHRYVLISNITGSHETK
YLSPFRMDNCSGSRRRDRLHVKLKSLRNKIHKQLHPNCRFDDATKTSDDKCVSYEVPE
RDGLATISLEEVFPKSNRCQIPEENLGETDSVIHRDLGNFANENDYPQWRKVESQYNL
ENVQPEEDEIVDRLRSEIRSTKLKSVKTTSRTLEKAIEARCTGKRVLQQLSCQSNQLT
KIESNCDMLKIQSNVADRKIDELAHENRSLLALKSPNPFRKKREREKRDQIYNLKLKH
RHLQQETMKRAQDSDKNLAINLSSEYGRYGQGVERQRILRDAQKYQFEADEEDNQMEI
DLYGNLEQIKAVSGDLKIMAHAFGREFEAQNTRMFDIENNVQQADNALQAKRYRLEKV
IGKRW"
gene 310208..311752
/locus_tag="YMR018W"
/db_xref="GeneID:855032"
mRNA 310208..311752
/locus_tag="YMR018W"
/product="hypothetical protein"
/transcript_id="NM_001182514.1"
/db_xref="GI:296147136"
/db_xref="GeneID:855032"
CDS 310208..311752
/locus_tag="YMR018W"
/note="hypothetical protein with similarity to human
PEX5Rp (peroxin protein 5 related protein); transcription
increases during colony development similar to genes
involved in peroxisome biogenesis; YMR018W is not an
essential gene"
/codon_start=1
/product="hypothetical protein"
/protein_id="NP_013731.1"
/db_xref="GI:6323660"
/db_xref="SGD:S000004620"
/db_xref="GeneID:855032"
/translation="MNEVTCSITGDNPIHKINNGLGLKWNNLGKFSDFQTNDSAARDA
RTIDYIFTNCQTGSSIGKIDFRAALPADKSQHSGVSEKEFSRLENQWSKEFSCFPKNK
NADVTKPSRNKHEKRSANLHNRYFAQYYSTAYQQNRIYPCRISYNEHSSVSNGWEFQF
KSIENQLLNELKIENNVEEKTVGYEYVAEYEETIDFMHMLSSVPQTYQFLKSNIYITE
RDPYKIGCVLMDNGSNLNEVVMAFEAAISQDPSHINAWLKLGIVNFENESESNGELAL
RNCLNLDPNNTIALENLAIHHINQQNESESLKLFHKWILSKFSKVFQPSAGENKDSIN
KIPKKAHLAHILESLLNMGIEKKDQYDIYSVLSILYYSDQKIKQSQKCLEFLLLEKPN
NGTIWNRYGAILANTKSYHSAINAYNKCKQLRPNFTRVRYNLAIAYMNKGDYVKASKM
LIEVILLRSKGYEHNKAKMQNKFMQNLKNALIASKNFDSLDLINGSHNTESLISTLKA
IYNKMD"
gene 312156..315005
/gene="STB4"
/locus_tag="YMR019W"
/db_xref="GeneID:855033"
mRNA 312156..315005
/gene="STB4"
/locus_tag="YMR019W"
/product="Stb4p"
/transcript_id="NM_001182515.1"
/db_xref="GI:296147137"
/db_xref="GeneID:855033"
CDS 312156..315005
/gene="STB4"
/locus_tag="YMR019W"
/note="Putative transcription factor; contains a
Zn(II)2Cys6 zinc finger domain characteristic of
DNA-binding proteins; computational analysis suggests a
role in regulation of expression of genes encoding
transporters; binds Sin3p in a two-hybrid assay"
/codon_start=1
/product="Stb4p"
/protein_id="NP_013732.1"
/db_xref="GI:6323661"
/db_xref="SGD:S000004621"
/db_xref="GeneID:855033"
/translation="MSINHEIYYILVFEHRSVAIKLIIVVIVLLQFFLARSRQIDRTW
AHTNRKERFREMTAIGNTDDALDTSTAASKENGKGRLRVQKACELCKKRKVKCDGNNP
CLNCSKHQKECRYDFKATNRKRRRRQVASAVRDVSKTYAETSESFPRDLLSKSNIIIN
APSDGVSSSASNSPNPNSHYHHISSTLPFMSGRPNHTFHSGSNLNGENNNNSFPEDHM
AKLLLQLSSKLGNTTKESSIRTTRTNASDVNANPTVVNMKNSQEDCDTNHRSAICDSA
EALHNNNINSKENKIINSQITNTVNDHFESPWQTFSLDKYRFHRRYQNILPYYLGVSI
LKDLSPQTIEYAKLKRPRVQNYGWNLSGGHYLKYKGDFRSQEKNIRHESKFFDFDDPV
HLSLINKLLRYYFDEINPVFSIIHEATFWQQYNNKFLRQGKQNNSSANLFTSMLYLIL
STTLRFREGHLDGQKGQGTYSNTSLNITFEEKSILIKKPSIEENLFKYAYLIINTLTF
EWESFELIQSWLLITFYFRTCYRQTACWNALSQAVNMCNGMSLYLNKFPEIHSTYDES
KAWHCFWCCFIMDKLISFQMGRFYQLSLPASEMCEQMNLVKSKKFLQEEDDWFHEETF
QMLDLSIIVTQFLKRDAQDLNLNETVQLRSQLGQWYDTFIVGSQTNAYDDNYRYFYQV
QPFMTYLDIRLTFEVRQLFCLIAPSSTANNKSLEYVVDTELLISHCQMAIENLAEITR
SNLFFVPWWLNLSQLFTVNLICIIYLHAGIAVTQNKAIMQSCQEIWRTLECSKPKNRP
SMLPECLWCLKMLNHMFCIRLRDSALQLEATLGTDHGDDTPNRNKFEQFKKVGDNDAD
VEVDAGEREENADERQENPHNNSKRVPLATRSHNTTNFDGSIAISPESAVANLGTDTG
LPSDVLDTVSKIGNSPNVFDDDLFSNLLWFDQNFA"
gene 315377..316903
/gene="FMS1"
/locus_tag="YMR020W"
/db_xref="GeneID:855034"
mRNA 315377..316903
/gene="FMS1"
/locus_tag="YMR020W"
/product="polyamine oxidase"
/transcript_id="NM_001182516.1"
/db_xref="GI:296147138"
/db_xref="GeneID:855034"
CDS 315377..316903
/gene="FMS1"
/locus_tag="YMR020W"
/note="Polyamine oxidase, converts spermine to spermidine,
which is required for the essential hypusination
modification of translation factor eIF-5A; also involved
in pantothenic acid biosynthesis"
/codon_start=1
/product="polyamine oxidase"
/protein_id="NP_013733.1"
/db_xref="GI:6323662"
/db_xref="SGD:S000004622"
/db_xref="GeneID:855034"
/translation="MNTVSPAKKKVIIIGAGIAGLKAASTLHQNGIQDCLVLEARDRV
GGRLQTVTGYQGRKYDIGASWHHDTLTNPLFLEEAQLSLNDGRTRFVFDDDNFIYIDE
ERGRVDHDKELLLEIVDNEMSKFAELEFHQHLGVSDCSFFQLVMKYLLQRRQFLTNDQ
IRYLPQLCRYLELWHGLDWKLLSAKDTYFGHQGRNAFALNYDSVVQRIAQSFPQNWLK
LSCEVKSITREPSKNVTVNCEDGTVYNADYVIITVPQSVLNLSVQPEKNLRGRIEFQP
PLKPVIQDAFDKIHFGALGKVIFEFEECCWSNESSKIVTLANSTNEFVEIVRNAENLD
ELDSMLEREDSQKHTSVTCWSQPLFFVNLSKSTGVASFMMLMQAPLTNHIESIREDKE
RLFSFFQPVLNKIMKCLDSEDVIDGMRPIENIANANKPVLRNIIVSNWTRDPYSRGAY
SACFPGDDPVDMVVAMSNGQDSRIRFAGEHTIMDGAGCAYGAWESGRREATRISDLLK
"
gene complement(317165..318418)
/gene="MAC1"
/locus_tag="YMR021C"
/gene_synonym="CUA1"
/db_xref="GeneID:855035"
mRNA complement(317165..318418)
/gene="MAC1"
/locus_tag="YMR021C"
/gene_synonym="CUA1"
/product="Mac1p"
/transcript_id="NM_001182517.1"
/db_xref="GI:296147139"
/db_xref="GeneID:855035"
CDS complement(317165..318418)
/gene="MAC1"
/locus_tag="YMR021C"
/gene_synonym="CUA1"
/note="Copper-sensing transcription factor involved in
regulation of genes required for high affinity copper
transport"
/codon_start=1
/product="Mac1p"
/protein_id="NP_013734.1"
/db_xref="GI:6323663"
/db_xref="SGD:S000004623"
/db_xref="GeneID:855035"
/translation="MIIFNGNKYACASCIRGHRSSTCRHSHRMLIKVRTRGRPSPMAI
RDAILVDSTSQSTEYENGAQIEGDCCSAMNQQPILFVRASAVRKARMINGKLHILMEE
GFTAHEPKDISTFTDDGNKYITETEFLRKHSPKAPATGTISPDSTKSSSSSEKKERSR
LQQEPIRHFSNCCKKDKSQNPASNGKTNKAPSDDIFTPYGSLESTSAFNDILQENYNS
SVPGAHDSSETLTPQSTTTIAAPHSSDVASKVEVLTHKGIFLSTQCSCEDESCPCVNC
LIHRSEEELNSYIQQSGVPLTNIGEAQITDKMMDYLDDCKCTDKECICPPDNCTCDGC
FSHSTNIIPFEKFFFYGILNARLTRKTQIKFKGKLVPSKYWWDFLKLQVPLMTDAQLE
LLDIHAWFQKLVSNYAPHLSDATTS"
gene 318680..319177
/gene="UBC7"
/locus_tag="YMR022W"
/gene_synonym="DER2; QRI8"
/db_xref="GeneID:855036"
mRNA 318680..319177
/gene="UBC7"
/locus_tag="YMR022W"
/gene_synonym="DER2; QRI8"
/product="E2 ubiquitin-conjugating protein UBC7"
/transcript_id="NM_001182518.1"
/db_xref="GI:296147140"
/db_xref="GeneID:855036"
CDS 318680..319177
/gene="UBC7"
/locus_tag="YMR022W"
/gene_synonym="DER2; QRI8"
/EC_number="6.3.2.19"
/note="Ubiquitin conjugating enzyme, involved in the
ER-associated protein degradation pathway; requires Cue1p
for recruitment to the ER membrane; proposed to be
involved in chromatin assembly"
/codon_start=1
/product="E2 ubiquitin-conjugating protein UBC7"
/protein_id="NP_013735.1"
/db_xref="GI:6323664"
/db_xref="SGD:S000004624"
/db_xref="GeneID:855036"
/translation="MSKTAQKRLLKELQQLIKDSPPGIVAGPKSENNIFIWDCLIQGP
PDTPYADGVFNAKLEFPKDYPLSPPKLTFTPSILHPNIYPNGEVCISILHSPGDDPNM
YELAEERWSPVQSVEKILLSVMSMLSEPNIESGANIDACILWRDNRPEFERQVKLSIL
KSLGF"
gene complement(319437..321017)
/gene="MSS1"
/locus_tag="YMR023C"
/gene_synonym="PET53"
/db_xref="GeneID:855037"
mRNA complement(319437..321017)
/gene="MSS1"
/locus_tag="YMR023C"
/gene_synonym="PET53"
/product="Mss1p"
/transcript_id="NM_001182519.1"
/db_xref="GI:296147141"
/db_xref="GeneID:855037"
CDS complement(319437..321017)
/gene="MSS1"
/locus_tag="YMR023C"
/gene_synonym="PET53"
/note="Mitochondrial protein, forms a heterodimer complex
with Mto1p that performs the 5-carboxymethylaminomethyl
modification of the wobble uridine base in mitochondrial
tRNAs; similar to human GTPBP3"
/codon_start=1
/product="Mss1p"
/protein_id="NP_013736.1"
/db_xref="GI:6323665"
/db_xref="SGD:S000004625"
/db_xref="GeneID:855037"
/translation="MNSASFLQSRLISRSFLVRRSLKRYSGLAKPYTFQQPTIYALST
PANQTSAIAIIRISGTHAKYIYNRLVDSSTVPPIRKAILRNIYSPSSCSVKPHDQKES
KILLDTSLLLYFQAPYSFTGEDVLELHVHGGKAVVNSILKAIGSLHDRSSGKDIRFAL
PGDFSRRAFQNGKFDLTQLEGIKDLIDSETESQRRSALSSFNGDNKILFENWRETIIE
NMAQLTAIIDFADDNSQEIQNTDEIFHNVEKNIICLRDQIVTFMQKVEKSTILQNGIK
LVLLGAPNVGKSSLVNSLTNDDISIVSDIPGTTRDSIDAMINVNGYKVIICDTAGIRE
KSSDKIEMLGIDRAKKKSVQSDLCLFIVDPTDLSKLLPEDILAHLSSKTFGNKRIIIV
VNKSDLVSDDEMTKVLNKLQTRLGSKYPILSVSCKTKEGIESLISTLTSNFESLSQSS
ADASPVIVSKRVSEILKNDVLYGLEEFFKSKDFHNDIVLATENLRYASDGIAKITGQA
IGIEEILDSVFSKFCIGK"
gene complement(321147..321219)
/locus_tag="tA(AGC)M1"
/db_xref="GeneID:855038"
tRNA complement(321147..321219)
/locus_tag="tA(AGC)M1"
/product="tRNA-Ala"
/note="Alanine tRNA (tRNA-Ala), predicted by tRNAscan-SE
analysis; one of 11 nuclear tRNA genes containing the
tDNA-anticodon AGC (converted to IGC in the mature tRNA),
decodes GCU and GCC codons into alanine, one of 16 nuclear
tRNAs for alanine"
/db_xref="SGD:S000006518"
/db_xref="GeneID:855038"
gene 321875..323047
/gene="MRPL3"
/locus_tag="YMR024W"
/db_xref="GeneID:855039"
mRNA 321875..323047
/gene="MRPL3"
/locus_tag="YMR024W"
/product="mitochondrial 54S ribosomal protein YmL3"
/transcript_id="NM_001182520.1"
/db_xref="GI:296147142"
/db_xref="GeneID:855039"
CDS 321875..323047
/gene="MRPL3"
/locus_tag="YMR024W"
/note="Mitochondrial ribosomal protein of the large
subunit"
/codon_start=1
/product="mitochondrial 54S ribosomal protein YmL3"
/protein_id="NP_013737.1"
/db_xref="GI:6323666"
/db_xref="SGD:S000004626"
/db_xref="GeneID:855039"
/translation="MGIVLKRAIAAGMKPFPNSTWHWSRTIRPFSQHLSSTCFLQQSS
RFTSKRYLHLSTLTQQEKRFLPESELAKYKEYYQGLKSTVNEIPESVASKSPSLRTLH
KRLQLPNELTYSTLSRCLTCPSAKLPDKINNPTKGAAFVNTVPTNKYLDNHGLNIMGK
NLLSYHVTKSIIQKYPRLPTVVLNAAVNAYISEAVLAHIAKYWGIEVETTSVLSRYLK
MEPFEFTLGRLKFFNNSLNSKDGIELITGKNFSETSALAMSVRSIIAAIWAVTEQKDS
QAVYRFIDDHIMSRKLDITKMFQFEQPTRELAMLCRREGLEKPVSKLVAESGRLSKSP
VFIVHVFSGEETLGEGYGSSLKEAKARAATDALMKWYCYEPLAQQEPVIDPGTVVV"
gene 323300..324187
/gene="CSI1"
/locus_tag="YMR025W"
/db_xref="GeneID:855040"
mRNA 323300..324187
/gene="CSI1"
/locus_tag="YMR025W"
/product="Csi1p"
/transcript_id="NM_001182521.1"
/db_xref="GI:296147143"
/db_xref="GeneID:855040"
CDS 323300..324187
/gene="CSI1"
/locus_tag="YMR025W"
/note="Subunit of the Cop9 signalosome, which is required
for deneddylation, or removal of the ubiquitin-like
protein Rub1p from Cdc53p (cullin); involved in adaptation
to pheromone signaling; functional equivalent of canonical
Csn6 subunit of the COP9 signalosome"
/codon_start=1
/product="Csi1p"
/protein_id="NP_013738.1"
/db_xref="GI:6323667"
/db_xref="SGD:S000004627"
/db_xref="GeneID:855040"
/translation="MDLLKFSSLAISEINFLHESSFDSIDHSWFLLIGCKLDQDDEIY
IPINGNEAESQWYIEKVIRIPMQENDKINQERLERRINLTKVTQKDICILGILDLCQL
EEDENITNKVTEKVLTQLTALALKYLIKYNVFRQHTSFQEAVNSLKGYKIENSVQIGA
EIILDFLQDKVQIKDVNDRYQIPTPNNTVDPGFDEFQLIDMKDKEINIQKYNNNTIRK
LLEKINRMIIFLKNYDATDKPFSSTQDVILRKISMLVTQLQRGGTSDMNYLLDNKINE
IKLLEISCKQWEISNMLKK"
gene complement(324236..325435)
/gene="PEX12"
/locus_tag="YMR026C"
/gene_synonym="PAS11"
/db_xref="GeneID:855041"
mRNA complement(324236..325435)
/gene="PEX12"
/locus_tag="YMR026C"
/gene_synonym="PAS11"
/product="ubiquitin-protein ligase peroxin 12"
/transcript_id="NM_001182522.1"
/db_xref="GI:296147144"
/db_xref="GeneID:855041"
CDS complement(324236..325435)
/gene="PEX12"
/locus_tag="YMR026C"
/gene_synonym="PAS11"
/note="C3HC4-type RING-finger peroxin and E3 ubiquitin
ligase, required for peroxisome biogenesis and peroxisomal
matrix protein import; forms translocation subcomplex with
Pex2p and Pex10p; mutations in human homolog cause
peroxisomal disorder"
/codon_start=1
/product="ubiquitin-protein ligase peroxin 12"
/protein_id="NP_013739.1"
/db_xref="GI:6323668"
/db_xref="SGD:S000004628"
/db_xref="GeneID:855041"
/translation="MSFYSNLPSAGQSSRGSSTSGRNGVGLEPLYPTIFEIMSSQEID
SLLPASIRYLLANHLVANFPNRYTLRLNKYFFEWFQAIKGFVEWYHLKTYNSTFIDRF
YGLQLFSSRDRNLALTQCLNPKGQSEWPQGLQLNQQQKSVIFLEKIILPYITAKLDEI
LEKISMNNIFSSDETENKWPKRAFLRIYPFIKKLLALSNLLVKLLFLTKRTGSVSLLQ
YLFKIEYTTVRPLSSELSGLKETKGMDNRLRKTNISSIFALMQGQLSIIPRFLTFMGS
QFFPTFIFVLRVYQWWTTQDMTTKLQKRVNDLDEDIPRPPFSSHSDKTEDKEGVSEAC
PVCEKTVQNPCVLETGYVACYPCAISYLVNNEGHCPVTNKKLLGCTYNKHTNKWEVVT
GIRKLLI"
gene 325877..327289
/locus_tag="YMR027W"
/db_xref="GeneID:855042"
mRNA 325877..327289
/locus_tag="YMR027W"
/product="hypothetical protein"
/transcript_id="NM_001182523.1"
/db_xref="GI:296147145"
/db_xref="GeneID:855042"
CDS 325877..327289
/locus_tag="YMR027W"
/note="hypothetical protein; green fluorescent protein
(GFP)-fusion protein localizes to the nucleus and
cytoplasm; YMR027W is not an essential gene"
/codon_start=1
/product="hypothetical protein"
/protein_id="NP_013740.1"
/db_xref="GI:6323669"
/db_xref="SGD:S000004629"
/db_xref="GeneID:855042"
/translation="MTIPGRFMTIDKGTFGEYTASTRWPIIIQNAIDDLSKHQETEKS
NGTKFEQGEVIKKELKEFRQEIIDRVPLRPFTEEEIKIANVPLSFNEYLKKHPEVNWG
AVEWLFSEVYLYRRVNVLFQRQCEWAKFDIFNRLKQSTFESSFYGVVELALRYENLLP
QLREMKQNPGNEIDDILKVLFKEFIEISLWGNATDLSLLTNATLEDIKSIQGAKARAA
SESKIVVNDTEKAWEVLTKARADANSREIRVDFVLDNSGFELYADLMLAAFLLQSGLA
TKCIFHAKDIPYMVSDVMLKDFDILVHDLRDREFFPSGEPSTKESRALDLFAGEMEKF
VSSGKIEFREDSFWTTELDYWNLDANETKYHGSILHKDLQKSNLVIFKGDLNYRKLTG
DRKWPRTTKWETAIGPLATNGITSLSLRTCKADVQVALPEGLDAKLSQEWEKENPGRG
SWWCCSGKWAVICFCSGIHK"
gene 327482..328582
/gene="TAP42"
/locus_tag="YMR028W"
/db_xref="GeneID:855043"
mRNA 327482..328582
/gene="TAP42"
/locus_tag="YMR028W"
/product="Tap42p"
/transcript_id="NM_001182524.1"
/db_xref="GI:296147146"
/db_xref="GeneID:855043"
CDS 327482..328582
/gene="TAP42"
/locus_tag="YMR028W"
/note="Essential protein involved in the TOR signaling
pathway; physically associates with the protein
phosphatase 2A and the SIT4 protein phosphatase catalytic
subunits"
/codon_start=1
/product="Tap42p"
/protein_id="NP_013741.1"
/db_xref="GI:6323670"
/db_xref="SGD:S000004630"
/db_xref="GeneID:855043"
/translation="MASVTEQFNDIISLYSTKLEHTSLRQDSPEYQGLLLSTIKKLLN
LKTAIFDRLALFSTNETIDDVSTASIKFLAVDYYLGLLISRRQSNDSDVAQRQSMKLI
YLKKSVESFINFLTLLQDYKLLDPLVGEKLGNFKDRYNPQLSELYAQPKNNKDLSGAQ
LKRKEKIELFQRNKEISTKLHCLELELKNNDEDHDHDELLRELYLMRLHHFSLDTINN
IEQNLFECEMLSNFLKNSVHEVKSSGTQIRKESNDDDSTGFTDKLENINKPLIDKKGQ
VLRNFTLVDKRQQLQQKVRGYGQYGPTMSVEEFLDKEFEEGRVLQGGEEPEQAPDEEN
MDWQDRETYKAREWDEFKESHAKGSGNTMNRG"
gene complement(328660..330231)
/gene="FAR8"
/locus_tag="YMR029C"
/db_xref="GeneID:855044"
mRNA complement(328660..330231)
/gene="FAR8"
/locus_tag="YMR029C"
/product="Far8p"
/transcript_id="NM_001182525.1"
/db_xref="GI:296147147"
/db_xref="GeneID:855044"
CDS complement(328660..330231)
/gene="FAR8"
/locus_tag="YMR029C"
/note="Protein involved in recovery from cell cycle arrest
in response to pheromone, in a Far1p-independent pathway;
interacts with Far3p, Far7p, Far9p, Far10p, and Far11p"
/codon_start=1
/product="Far8p"
/protein_id="NP_013742.1"
/db_xref="GI:6323671"
/db_xref="SGD:S000004631"
/db_xref="GeneID:855044"
/translation="MAINQAHVHPHYTLPGVMHYLQTEFTKNERDRITWELERSEMKA
RIAELEGENRDLKHQLNQIQSKAVSPEGEKEEKHVPDSLLQSKLAVQENVKEIIYLLK
GPNTVNQLESLNSREAGSELHDLEKLNVNTPKEEGSAKTNGMDILNNALLDTKPNPKQ
GPSESPSPTKVKSLFSTANKRENNETISKIHSELSKVDIISSYGDCMALYDADTKSLE
IHQVDANLNSKLLKKISLGQDSDIMKFFWVSTSKLLVIEKSFHLKLFSISSASLISDV
DLLQDSEQPFSSSDIINIDFKNKWLLIASKNKSQIRIWELDNIEAPEDVPINIKETYE
ITHDNDDDDSNDSTNILDCILGITEKSLILLSSNPYQLTIYDFEGKLLQKIDLKIDTI
LSGKPEEEGYHLFLDRKTSKLLIQLSNERLLVYSFDKKKVVLKEQLTPSSTLPIQLDL
NDSIITVSYSNGDFEFRNLENLKPSIDEFVVADINFSERKEPVVFSSNLIVDSTPVLI
TVNKNNEVLLHKIKI"
gene 330793..331923
/gene="RSF1"
/locus_tag="YMR030W"
/db_xref="GeneID:855045"
mRNA 330793..331923
/gene="RSF1"
/locus_tag="YMR030W"
/product="Rsf1p"
/transcript_id="NM_001182526.1"
/db_xref="GI:296147148"
/db_xref="GeneID:855045"
CDS 330793..331923
/gene="RSF1"
/locus_tag="YMR030W"
/note="Protein required for respiratory growth; localized
to both the nucleus and mitochondrion; may interact with
transcription factors to mediate the transition to
respiratory growth and activate transcription of nuclear
and mitochondrial genes"
/codon_start=1
/product="Rsf1p"
/protein_id="NP_013743.1"
/db_xref="GI:6323672"
/db_xref="SGD:S000004632"
/db_xref="GeneID:855045"
/translation="MKDLNPEMGKFATTKGPPQDNRGMVDIATLPNFPANRSGTPREE
MYLAPNKMETPRILNMNMVPDYLQKENFSPDFSSATVSAKSSPVNVTHDESLPLGTIE
SNSTKDSKYAVQRQQQQVVDFIENNMQLLSSETLNFRSDIMKTLELPIPKRRDIKGNH
LSKLLFAKSPLTINTYCQFYDRRTKRICNQEMIWKDKNSREKHGSRKYQRHLSKVHDV
QLTPNNFTEFFDHNSPLFQECYDYQSRLMRDLLVEPDAKFKEKKKKKKGDVNGNHPET
GSSLINHQVQQQNVRELQSKIAMNDLIEILIDLNIPFSVLDYQPMRNWLIKYSIISTD
TLPDEVYFKTDPGVNELEHNSSNLNNSNSGTPHNHNQNQHTN"
gene complement(332212..334743)
/gene="EIS1"
/locus_tag="YMR031C"
/db_xref="GeneID:855047"
mRNA complement(332212..334743)
/gene="EIS1"
/locus_tag="YMR031C"
/product="Eis1p"
/transcript_id="NM_001182527.1"
/db_xref="GI:296147149"
/db_xref="GeneID:855047"
CDS complement(332212..334743)
/gene="EIS1"
/locus_tag="YMR031C"
/note="Component of the eisosome required for proper
eisosome assembly; similarity to Ykl050cp and Uso1p; the
authentic, non-tagged protein is detected in a
phosphorylated state in highly purified mitochondria in
high-throughput studies; protein increases in abundance
and relocalizes from plasma membrane to cytoplasm upon DNA
replication stress"
/codon_start=1
/product="Eis1p"
/protein_id="NP_013744.1"
/db_xref="GI:6323674"
/db_xref="SGD:S000004633"
/db_xref="GeneID:855047"
/translation="MSLISAVEDRDIHNIGKTSGGGSRTSSITSSKKSLKHGSKSLRK
PKVYQTTGEPLSREALYKAKLKYGVYQSPAQSYSIGVSDAHAASDKAANLAHDNQTTV
EAYKRMFIDPNATKAASKMGPKVVRNNSITSATSKTSKESQTKRKSKESPGAAASKAY
SMTMETTSLSSQTNSRSYSITSASSVLSGASGSFNSTVNPKPKTLNLEKVLVGAEKKA
ESRIKERWEPEKTNFQYGVKTDEHGNLNQFSFSNEMMNNIMAKVDAPKAQDLQKVKKV
SAEKEAKSMKFALGAANAVKDMHPGEDIDKSIALKAQKRETYLSQLTSQQVLTLARAN
VDRQLDIIEKSDMHRKLFTNMEYNKAAVAVAQSNHQKKTEFHNKINMGGGLFLSPEDI
TKIASGLISPVLGEVSERAEAQRAMDEEIAERTEAYNKSSNEWETMERSIISNDAKVL
TTTANRHQTEKKTSQEKIKASFDALVARMDTKVAERETLLEDTKSKEIEFKKQMQQEL
KDEKARLDQDLEEWGKKCEQDITEARKEQEELLKPYHDDLANAEAEHKTLVEERDEIN
AEISRLQDAIVDHKRKISGYGNDLDAQKNRNIREDDKLLELGQTKESLESHLNDDVII
LANKAKEQAELSTKEARLKQLEVDSLINERKSELNATEIELKKEKLNLLEAMKDVASA
RGDDKIDEEKVKKLIGMTSEEYLTQNKSVEKNVEDLPTQLEKIEEGDELKKEEIVGAE
TKNSGGDGVPVSTAAKEATETSSAVQTKEPEEKISIGNKSSGKEDANDCKSAEHSKEI
SVSQKAGNNKSLGVSPDSLEHTFSGFSQGSSIEDDQDAISNQEKK"
gene 335298..337307
/gene="HOF1"
/locus_tag="YMR032W"
/gene_synonym="CYK2"
/db_xref="GeneID:855048"
mRNA 335298..337307
/gene="HOF1"
/locus_tag="YMR032W"
/gene_synonym="CYK2"
/product="Hof1p"
/transcript_id="NM_001182529.1"
/db_xref="GI:296147150"
/db_xref="GeneID:855048"
CDS 335298..337307
/gene="HOF1"
/locus_tag="YMR032W"
/gene_synonym="CYK2"
/note="Bud neck-localized, SH3 domain-containing protein
required for cytokinesis; regulates actomyosin ring
dynamics and septin localization; interacts with the
formins, Bni1p and Bnr1p, and with Cyk3p, Vrp1p, and
Bni5p"
/codon_start=1
/product="Hof1p"
/protein_id="NP_013746.1"
/db_xref="GI:6323675"
/db_xref="SGD:S000004635"
/db_xref="GeneID:855048"
/translation="MSYSYEACFWDPNDNGVNILLGHISQGIRSCDSMILFFKQRSEL
EKDYARRLGAITGKLDKDIGTNMDYGKLNETFNVVLSVEKARAQSHSKQSEILFRQIY
TDTKAFAANLQARYTTLSGKIERLRMDKFNKKKGCEVLQKKLQDAQIRFRDLQLNENN
MIGAKRVEHNKRELLKWESNSQEYKVQLDVLKQEYKASQKFWIHEWAQLSCELQEMEN
ARISFLQSKLQQFATSSMETYILEQTKMDMLTNHLNSFTAADEISTFSKENGTGRLKH
KTSKGDMNSSANWAQMSSISTTSKKTESYMDNIRKLSSQLKETENKRKLASIDKYEKP
LPSPEVTMATQFRNSTPVIRNETKVVANPTLSLRSSPVQLQSNVDDSVLRQKPDKPRP
IVGEEQLKPDEDSKNPDEKGLMVHKRNQSLSSPSESSSSNPTDFSHIKKRQSMESMTT
SVSSMANSIDDSQRFAKSWNSSNRKRKSMSHLQVPSSASSRSDDGGRTPNSAHNLNED
DYNTRRDTSTSTILFKPPVAVRGTSRGHTHRQSMIMQDSSNPIEDALYEMERIQSSSK
PGTKTGNIMDERGVVRDRGITVTLPIVTSEGFPVIEYAKAMYPLIGNEAPGLANFHKG
DYLLITEIVNKDWYKGEVYDNDRIDRNHRIGLIPYNFIQLLHQGL"
gene 337313..337603
/locus_tag="YMR030W-A"
/db_xref="GeneID:1466499"
mRNA 337313..337603
/locus_tag="YMR030W-A"
/product="hypothetical protein"
/transcript_id="NM_001184572.1"
/db_xref="GI:296147151"
/db_xref="GeneID:1466499"
CDS 337313..337603
/locus_tag="YMR030W-A"
/codon_start=1
/product="hypothetical protein"
/protein_id="NP_878141.1"
/db_xref="GI:33438853"
/db_xref="SGD:S000028574"
/db_xref="GeneID:1466499"
/translation="MYINFTSFLIKEKKYNVRFLLSRNRKIYAAVGEGHLSGFVTKNH
KISRLSFIFSKKKKVFFTIFDTIITIIVRSGIPFPLLCSFGRNKIYILFNVL"
gene 337788..339277
/gene="ARP9"
/locus_tag="YMR033W"
/gene_synonym="RSC12; SWP59"
/db_xref="GeneID:855049"
mRNA join(337788..337817,337904..339277)
/gene="ARP9"
/locus_tag="YMR033W"
/gene_synonym="RSC12; SWP59"
/product="Arp9p"
/transcript_id="NM_001182530.1"
/db_xref="GI:296147152"
/db_xref="GeneID:855049"
CDS join(337788..337817,337904..339277)
/gene="ARP9"
/locus_tag="YMR033W"
/gene_synonym="RSC12; SWP59"
/note="Component of both the SWI/SNF and RSC chromatin
remodeling complexes; actin-related protein involved in
transcriptional regulation"
/codon_start=1
/product="Arp9p"
/protein_id="NP_013747.1"
/db_xref="GI:6323676"
/db_xref="SGD:S000004636"
/db_xref="GeneID:855049"
/translation="MAPFRQDSILIIYPRSQTTLVQFGLNEETFTVPELEIPTQIYRT
TRQDGSYTYHSTNKDNKAELIKPIQNGEIIDISAFTQFLRLIFVSILSDRANKNQDAF
EAELSNIPLLLITHHSWSQSDLEIITQYVFESLEINNLIQLPASLAATYSMISLQNCC
IIDVGTHHTDIIPIVDYAQLDHLVSSIPMGGQSINDSLKKLLPQWDDDQIESLKKSPI
FEVLSDDAKKLSSFDFGNENEDEDEGTLNVAEIITSGRDTREVLEERERGQKVKNVKN
SDLEFNTFWDEKGNEIKVGKQRFQGCNNLIKNISNRVGLTLDNIDDINKAKAVWENII
IVGGTTSISGFKEALLGQLLKDHLIIEPEEEKSKREEEAKSVLPAATKKKSKFMTNST
AFVPTIEYVQCPTVIKLAKYPDYFPEWKKSGYSEIIFLGAQIVSKQIFTHPKDTFYIT
REKYNMKGPAALWDVQF"
gene complement(339418..340722)
/locus_tag="YMR034C"
/db_xref="GeneID:855050"
mRNA complement(339418..340722)
/locus_tag="YMR034C"
/product="hypothetical protein"
/transcript_id="NM_001182531.1"
/db_xref="GI:296147153"
/db_xref="GeneID:855050"
CDS complement(339418..340722)
/locus_tag="YMR034C"
/note="Putative transporter, member of the SLC10 carrier
family; identified in a transposon mutagenesis screen as a
gene involved in azole resistance; YMR034C is not an
essential gene"
/codon_start=1
/product="hypothetical protein"
/protein_id="NP_013748.1"
/db_xref="GI:6323677"
/db_xref="SGD:S000004637"
/db_xref="GeneID:855050"
/translation="MKTQYSLIRKIWAHSVTEFLKSQWFFICLAILIVIARFAPNFAR
DGGLIKGQYSIGYGCVAWIFLQSGLGMKSRSLMANMLNWRAHATILVLSFLITSSIVY
GFCCAVKAANDPKIDDWVLIGLILTATCPTTVASNVIMTTNAGGNSLLCVCEVFIGNL
LGAFITPALVQMFTNRAPFAYGNPATGNGIGALYGRVMKQVGLSVFVPLFVGQVIQNC
FPKGTAYYLGFLKKYHIKIGSYMLLLIMFSSFSTAFYQDAFTSVSHVCIIFLCFFNLG
IYIFFTGLSYLCARPWFILKLFPHEPIEGKSTRLYRYSYNIFRPFYYSKEDAICIMFC
GPAKTAALGVSLITSQYGDKKEHLGKLLVPLVLYQVEQVMTANFFVSLFKRWIQKDAQ
ADGSESSCANENEEVDLEKIISIGTGENQSVLSNNVPYTQPR"
gene 341142..341675
/gene="IMP2"
/locus_tag="YMR035W"
/db_xref="GeneID:855051"
mRNA 341142..341675
/gene="IMP2"
/locus_tag="YMR035W"
/product="Imp2p"
/transcript_id="NM_001182532.1"
/db_xref="GI:296147154"
/db_xref="GeneID:855051"
CDS 341142..341675
/gene="IMP2"
/locus_tag="YMR035W"
/EC_number="3.4.21.-"
/note="Catalytic subunit of the mitochondrial inner
membrane peptidase complex, required for maturation of
mitochondrial proteins of the intermembrane space; complex
contains Imp1p and Imp2p (both catalytic subunits), and
Som1p"
/codon_start=1
/product="Imp2p"
/protein_id="NP_013749.1"
/db_xref="GI:6323678"
/db_xref="SGD:S000004638"
/db_xref="GeneID:855051"
/translation="MFRAGSSKRFLRNTLIAISWVPVLLTINNNVVHIAQVKGTSMQP
TLNPQTETLATDWVLLWKFGVKNPSNLSRDDIILFKAPTNPRKVYCKRVKGLPFDTID
TKFPYPKPQVNLPRGHIWVEGDNYFHSIDSNTFGPISSGLVIGKAITIVWPPSRWGTD
LKLSTGRDCISKRAILE"
gene complement(341856..343520)
/gene="MIH1"
/locus_tag="YMR036C"
/db_xref="GeneID:855052"
mRNA complement(341856..343520)
/gene="MIH1"
/locus_tag="YMR036C"
/product="Mih1p"
/transcript_id="NM_001182533.1"
/db_xref="GI:296147155"
/db_xref="GeneID:855052"
CDS complement(341856..343520)
/gene="MIH1"
/locus_tag="YMR036C"
/EC_number="3.1.3.48"
/note="Protein tyrosine phosphatase involved in cell cycle
control; regulates the phosphorylation state of Cdc28p;
homolog of S. pombe cdc25"
/codon_start=1
/product="Mih1p"
/protein_id="NP_013750.1"
/db_xref="GI:6323679"
/db_xref="SGD:S000004639"
/db_xref="GeneID:855052"
/translation="MNNIFHGTEDECANEDVLSFQKISLKSPFGKKKNIFRNVQTFFK
SKSKHSNVDDDLINKENLAFDKSPLLTNHRSKEIDGPSPNIKQLGHRDELDENENEND
DIVLSMHFASQTLQSPTRNSSRRSLTNNRDNDLLSRIKYPGSPQRSSSFSRSRSLSRK
PSMNSSSNSSRRVQRQDGKIPRSSRKSSQKFSNITQNTLNFTSASSSPLAPNSVGVKC
FESCLAKTQIPYYYDDRNSNDFFPRISPETLKNILQNNMCESFYNSCRIIDCRFEYEY
TGGHIINSVNIHSRDELEYEFIHKVLHSDTSNNNTLPTLLIIHCEFSSHRGPSLASHL
RNCDRIINQDHYPKLFYPDILILDGGYKAVFDNFPELCYPRQYVGMNSQENLLNCEQE
MDKFRRESKRFATKNNSFRKLASPSNPNFFYRDSHQSSTTMASSALSFRFEPPPKLSL
NHRRVSSGSSLNSSESTGDENFFPILSKSSMSSNSNLSTSHMLLMDGLDTPSYFSFED
ERGNHQQVSGDEEQDGDFTFVGSDREDLPRPARRSLFPSLETEDKK"
gene complement(344403..346517)
/gene="MSN2"
/locus_tag="YMR037C"
/db_xref="GeneID:855053"
mRNA complement(344403..346517)
/gene="MSN2"
/locus_tag="YMR037C"
/product="Msn2p"
/transcript_id="NM_001182534.1"
/db_xref="GI:296147156"
/db_xref="GeneID:855053"
CDS complement(344403..346517)
/gene="MSN2"
/locus_tag="YMR037C"
/note="Transcriptional activator; activated in stress
conditions, which results in translocation from the
cytoplasm to the nucleus; binds DNA at stress response
elements of responsive genes, inducing gene expression;
MSN2 has a paralog, MSN4, that arose from the whole genome
duplication; relative distribution to the nucleus
increases upon DNA replication stress"
/codon_start=1
/product="Msn2p"
/protein_id="NP_013751.1"
/db_xref="GI:6323680"
/db_xref="SGD:S000004640"
/db_xref="GeneID:855053"
/translation="MTVDHDFNSEDILFPIESMSSIQYVENNNPNNINNDVIPYSLDI
KNTVLDSADLNDIQNQETSLNLGLPPLSFDSPLPVTETIPSTTDNSLHLKADSNKNRD
ARTIENDSEIKSTNNASGSGANQYTTLTSPYPMNDILYNMNNPLQSPSPSSVPQNPTI
NPPINTASNETNLSPQTSNGNETLISPRAQQHTSIKDNRLSLPNGANSNLFIDTNPNN
LNEKLRNQLNSDTNSYSNSISNSNSNSTGNLNSSYFNSLNIDSMLDDYVSSDLLLNDD
DDDTNLSRRRFSDVITNQFPSMTNSRNSISHSLDLWNHPKINPSNRNTNLNITTNSTS
SSNASPNTTTMNANADSNIAGNPKNNDATIDNELTQILNEYNMNFNDNLGTSTSGKNK
SACPSSFDANAMTKINPSQQLQQQLNRVQHKQLTSSHNNSSTNMKSFNSDLYSRRQRA
SLPIIDDSLSYDLVNKQDEDPKNDMLPNSNLSSSQQFIKPSMILSDNASVIAKVATTG
LSNDMPFLTEEGEQNANSTPNFDLSITQMNMAPLSPASSSSTSLATNHFYHHFPQQGH
HTMNSKIGSSLRRRKSAVPLMGTVPLTNQQNNISSSSVNSTGNGAGVTKERRPSYRRK
SMTPSRRSSVVIESTKELEEKPFHCHICPKSFKRSEHLKRHVRSVHSNERPFACHICD
KKFSRSDNLSQHIKTHKKHGDI"
gene complement(347511..348260)
/gene="CCS1"
/locus_tag="YMR038C"
/gene_synonym="LYS7"
/db_xref="GeneID:855054"
mRNA complement(347511..348260)
/gene="CCS1"
/locus_tag="YMR038C"
/gene_synonym="LYS7"
/product="Ccs1p"
/transcript_id="NM_001182535.1"
/db_xref="GI:296147157"
/db_xref="GeneID:855054"
CDS complement(347511..348260)
/gene="CCS1"
/locus_tag="YMR038C"
/gene_synonym="LYS7"
/note="Copper chaperone for superoxide dismutase Sod1p;
involved in oxidative stress protection; Met-X-Cys-X2-Cys
motif within the N-terminal portion is involved in
insertion of copper into Sod1p under conditions of copper
deprivation; protein abundance increases in response to
DNA replication stress"
/codon_start=1
/product="Ccs1p"
/protein_id="NP_013752.1"
/db_xref="GI:6323681"
/db_xref="SGD:S000004641"
/db_xref="GeneID:855054"
/translation="MTTNDTYEATYAIPMHCENCVNDIKACLKNVPGINSLNFDIEQQ
IMSVESSVAPSTIINTLRNCGKDAIIRGAGKPNSSAVAILETFQKYTIDQKKDTAVRG
LARIVQVGENKTLFDITVNGVPEAGNYHASIHEKGDVSKGVESTGKVWHKFDEPIECF
NESDLGKNLYSGKTFLSAPLPTWQLIGRSFVISKSLNHPENEPSSVKDYSFLGVIARS
AGVWENNKQVCACTGKTVWEERKDALANNIK"
gene complement(348644..349522)
/gene="SUB1"
/locus_tag="YMR039C"
/gene_synonym="TSP1"
/db_xref="GeneID:855055"
mRNA complement(348644..349522)
/gene="SUB1"
/locus_tag="YMR039C"
/gene_synonym="TSP1"
/product="Sub1p"
/transcript_id="NM_001182536.1"
/db_xref="GI:296147158"
/db_xref="GeneID:855055"
CDS complement(348644..349522)
/gene="SUB1"
/locus_tag="YMR039C"
/gene_synonym="TSP1"
/note="Transcriptional coactivator; facilitates elongation
through factors that modify RNAP II; role in peroxide
resistance involving Rad2p; role in the hyperosmotic
stress response through polymerase recruitment at RNAP II
and RNAP III genes; protein abundance increases in
response to DNA replication stress"
/codon_start=1
/product="Sub1p"
/protein_id="NP_013753.1"
/db_xref="GI:6323682"
/db_xref="SGD:S000004642"
/db_xref="GeneID:855055"
/translation="MSYYNRYRNKRRSDNGGGNLSNSNNNNGGMPSGLSASDAIFDLG
KNKRVTVRQFRNINLIDIREYYLDSSTGEMKPGKKGISLTEDLYDELLKHRLNIDEAL
RRLGSKRPKTKMVRLLSDDEYEDDNNNDSTNNDKDKNGKDKNSPKKRREDKSKASNES
HDLEPRSKKKKPAPPTLLPHEENIQNAEREANATLIIPGQAGRKQQEERKQKEKEEAE
EAKAKAVAEQEKEAKAKEKIAEPEPEPVPTLQAKKEDIVSNINESKDANSSDEEFAQS
LEAEMNKAEDDISEEE"
gene 350381..350863
/gene="YET2"
/locus_tag="YMR040W"
/db_xref="GeneID:855056"
mRNA 350381..350863
/gene="YET2"
/locus_tag="YMR040W"
/product="Yet2p"
/transcript_id="NM_001182537.1"
/db_xref="GI:296147159"
/db_xref="GeneID:855056"
CDS 350381..350863
/gene="YET2"
/locus_tag="YMR040W"
/note="hypothetical protein that may interact with
ribosomes, based on co-purification experiments; homolog
of human BAP31 protein"
/codon_start=1
/product="Yet2p"
/protein_id="NP_013754.1"
/db_xref="GI:6323683"
/db_xref="SGD:S000004643"
/db_xref="GeneID:855056"
/translation="MGVYLAVLFSLLVIEMAILFILVLPLPQRMRRWLYIRYSIISTN
KKFRTYMVGIMIFVGLLFIDSWKRSQIRVSTYRNQKNPYIINSVTPVDALASRAYNQR
NVYISGFIIYFYICILTVMSILRRIVEWNDKMKAGDDILKEKLRRKQKYLEELQKKKF
"
gene complement(350966..351973)
/gene="ARA2"
/locus_tag="YMR041C"
/db_xref="GeneID:855057"
mRNA complement(350966..351973)
/gene="ARA2"
/locus_tag="YMR041C"
/product="D-arabinose 1-dehydrogenase (NAD(P)(+)) ARA2"
/transcript_id="NM_001182538.1"
/db_xref="GI:296147160"
/db_xref="GeneID:855057"
CDS complement(350966..351973)
/gene="ARA2"
/locus_tag="YMR041C"
/EC_number="1.1.1.116"
/note="NAD-dependent arabinose dehydrogenase, involved in
biosynthesis of dehydro-D-arabinono-1,4-lactone; similar
to plant L-galactose dehydrogenase"
/codon_start=1
/product="D-arabinose 1-dehydrogenase (NAD(P)(+)) ARA2"
/protein_id="NP_013755.1"
/db_xref="GI:6323684"
/db_xref="SGD:S000004644"
/db_xref="GeneID:855057"
/translation="MVNEKVNPFDLASVSPLVLGGAILNQQYTDEPESIPLEDIIKYA
FSHGINAIDTSPYYGPSEVLYGRALSNLRNEFPRDTYFICTKVGRIGAEEFNYSRDFV
RFSVHRSCERLHTTYLDLVYLHDVEFVKFPDILEALKELRTLKNKGVIKNFGISGYPI
DFITWLAEYCSTEESDIGSLDAVLSYCNLNLQNNKLLNFRERLLRNAKLKMVCNASIL
SMSLLRSQETRQFHPCSHELRECASQAAKYCQEQNVDLADLATRYAISEWVGKGPVVL
GVSSMEELKLALDNYEIVKSNGNRLSSKDGQLVEYIQKNIFKEHFNEEWSSGIPHPEM
I"
gene 352280..352370
/locus_tag="tF(GAA)M"
/db_xref="GeneID:855058"
tRNA join(352280..352316,352335..352370)
/locus_tag="tF(GAA)M"
/product="tRNA-Phe"
/note="Phenylalanine tRNA (tRNA-Phe), predicted by
tRNAscan-SE analysis"
/db_xref="SGD:S000006568"
/db_xref="GeneID:855058"
gene 352603..353136
/gene="ARG80"
/locus_tag="YMR042W"
/gene_synonym="ARGR1"
/db_xref="GeneID:855059"
mRNA 352603..353136
/gene="ARG80"
/locus_tag="YMR042W"
/gene_synonym="ARGR1"
/product="Arg80p"
/transcript_id="NM_001182539.1"
/db_xref="GI:296147161"
/db_xref="GeneID:855059"
CDS 352603..353136
/gene="ARG80"
/locus_tag="YMR042W"
/gene_synonym="ARGR1"
/note="Transcription factor involved in regulation of
arginine-responsive genes; acts with Arg81p and Arg82p"
/codon_start=1
/product="Arg80p"
/protein_id="NP_013756.1"
/db_xref="GI:6323685"
/db_xref="SGD:S000004645"
/db_xref="GeneID:855059"
/translation="MTSNSDGSSTSPVEKPITGDVETNEPTKPIRRLSTPSPEQDQEG
DFDEEDDDDKFSVSTSTPTPTITKTKDSSDTSTVTRRKQPIRYIENKTRRHVTFSKRR
HGIMKKAYELSVLTGANILLLILANSGLVYTFTTPKLEPVVREDEGKSLIRACINASD
TPDATDTSPAQEQSPAN"
gene 353871..354731
/gene="MCM1"
/locus_tag="YMR043W"
/gene_synonym="FUN80"
/db_xref="GeneID:855060"
mRNA 353871..354731
/gene="MCM1"
/locus_tag="YMR043W"
/gene_synonym="FUN80"
/product="Mcm1p"
/transcript_id="NM_001182540.1"
/db_xref="GI:296147162"
/db_xref="GeneID:855060"
CDS 353871..354731
/gene="MCM1"
/locus_tag="YMR043W"
/gene_synonym="FUN80"
/note="Transcription factor involved in cell-type-specific
transcription and pheromone response; plays a central role
in the formation of both repressor and activator
complexes"
/codon_start=1
/product="Mcm1p"
/protein_id="NP_013757.1"
/db_xref="GI:6323686"
/db_xref="SGD:S000004646"
/db_xref="GeneID:855060"
/translation="MSDIEEGTPTNNGQQKERRKIEIKFIENKTRRHVTFSKRKHGIM
KKAFELSVLTGTQVLLLVVSETGLVYTFSTPKFEPIVTQQEGRNLIQACLNAPDDEEE
DEEEDGDDDDDDDDDGNDMQRQQPQQQQPQQQQQVLNAHANSLGHLNQDQVPAGALKQ
EVKSQLLGGANPNQNSMIQQQQHHTQNSQPQQQQQQQPQQQMSQQQMSQHPRPQQGIP
HPQQSQPQQQQQQQQQLQQQQQQQQQQPLTGIHQPHQQAFANAASPYLNAEQNAAYQQ
YFQEPQQGQY"
gene 355384..356811
/gene="IOC4"
/locus_tag="YMR044W"
/db_xref="GeneID:855061"
mRNA 355384..356811
/gene="IOC4"
/locus_tag="YMR044W"
/product="Ioc4p"
/transcript_id="NM_001182541.1"
/db_xref="GI:296147163"
/db_xref="GeneID:855061"
CDS 355384..356811
/gene="IOC4"
/locus_tag="YMR044W"
/note="Member of a complex (Isw1b) with Isw1p and Ioc2p;
interacts directly with H3K36me3 nucleosomes through its
PWWP domain to recruit the Isw1b complex to open reading
frames in a Set2p-dependent manner; Isw1b exhibits
nucleosome-stimulated ATPase activity and acts within
coding regions to coordinate transcription elongation with
termination and processing"
/codon_start=1
/product="Ioc4p"
/protein_id="NP_013758.1"
/db_xref="GI:6323687"
/db_xref="SGD:S000004647"
/db_xref="GeneID:855061"
/translation="MSEAIFQPTDIVLAKVKGFSAWPAMIIPNELIPDNILKTKPVSV
HKGKSGSDKKANEDIDADMESEARDREQSEEEEDIEDFGESEANPEKFIIYTPVLKFR
KNDTLKSTYCVKFFCDDSYIWVKPMDMKILTSEDCRKWLSGKQRKNKKLIPAYEMAMR
GKNGIDIWEFVEYGSYGKPDEEEYVEEEEEENEPEKKAIRPTRSSSRQRQKRASETEK
SEGGNSNKRKRVTRSTRQQAIDASEEEEEEEEEKVQEAVRKRPQRTKTKKVVVSKTKP
NPKTKAKKEKPKPPKPIKYHFEDDEDWSIVGLGPQDLSIEKTMDPIAKKLSQKKNLEK
HVEIKLDLEDKLAGINKLLCDVLCSAINQAVSIKDDFEIILDELQIALDTRGSRNEFI
TIFQSNNSLLLNFRILFNLRKRELNKWDLWDRFQDIFKHIYSYQFIPDTEDWQLEQNM
EIEEMDREKPSFSEDVKEEESKVGA"
mobile_element complement(357005..362918)
/note="YMRCTy1-3; Ty1 element, LTR retrotransposon of the
Copia (Pseudoviridae) group; contains co-transcribed genes
TYA Gag and TYB Pol, encoding proteins involved in
structure and function of virus-like particles, flanked by
two direct repeats"
/mobile_element_type="retrotransposon:YMRCTy1-3"
/db_xref="SGD:S000007119"
LTR complement(357005..357336)
/note="Ty1 LTR"
/db_xref="SGD:S000007109"
gene complement(357359..362627)
/locus_tag="YMR045C"
/db_xref="GeneID:855062"
mRNA complement(join(<357359..361321,361323..>362627))
/locus_tag="YMR045C"
/transcript_id="NM_001182542.1"
/db_xref="GI:296147164"
/db_xref="GeneID:855062"
CDS complement(join(357359..361321,361323..362627))
/locus_tag="YMR045C"
/EC_number="2.7.7.49"
/EC_number="3.4.23.-"
/EC_number="3.1.26.4"
/EC_number="2.7.7.7"
/ribosomal_slippage
/note="Retrotransposon TYA Gag and TYB Pol genes;
transcribed/translated as one unit; polyprotein is
processed to make a nucleocapsid-like protein (Gag),
reverse transcriptase (RT), protease (PR), and integrase
(IN); similar to retroviral genes"
/codon_start=1
/product="gag-pol fusion protein"
/protein_id="NP_013759.1"
/db_xref="GI:6323688"
/db_xref="SGD:S000004648"
/db_xref="GeneID:855062"
/translation="MESQQLSQHSPISHGSACASVTSKEVQTTQDPLDISASKTEECE
KVSTQANSQQPTTPLSSAVPENHHHASPQAAQVPLPQNGPYPQQRMMNTQQANISGWP
VYGHPSLMPYPPYQMSPMYAPPGAQSQFTQYPQYVGTHLNTPSPESGNSFPDSSSAKS
NMTSTNQHVRPPPILTSPNDFLNWVKIYIKFLQNSNLGDIIPTATRKAVRQMTDDELT
FLCHTFQLFAPSQFLPPWVKDILSVDYTDIMKILSKSINKMQSDTQEVNDITTLATLH
YNGSTPADAFEAEVTNILDRLNNNGIPINNKVACQFIMRGLSGEYKFLRYARHRCIHM
TVADLFSDIHSMYEEQQESKRNKSTHRRSPSDEKKDSRTYTNTTKPKSITRNSQKPNN
SQSRTARAHNVSTFNNSPGPDNDLIRGSTTEPIQLKNTHDLHLGQELTESTVNHTNHS
DDKLPGHLLLDSGASRTLIRSAHHIHSASSNPDINVVDAQKRNIPINAIGDLQFHFQD
NTKTSIKVLHTPNIAYDLLSLNELAAVDITACFTKNVLERSDGTVLAPIVKYGDFYWV
SKKYLLPSNISVPTINNVHTSESTRKYPYPFIHRMLAHANAQTIRYSLKNNTITYFNE
SDVDWSSAIDYQCPDCLIGKSTKHRHIKGSRLKYQNSYEPFQYLHTDIFGPVHNLPKS
APSYFISFTDETTKFRWVYPLHDRREDSILDVFTTILAFIKNQFQASVLVIQMDRGSE
YTNRTLHKFLEKNGITPCYTTTADSRAHGVAERLNRTLLDDCRTQLQCSGLPNHLWFS
AIEFSTIVRNSLASPKSKKSARQHAGLAGLDISTLLPFGQPVIVNDHNPNSKIHPRGI
PGYALHPSRNSYGYIIYLPSLKKTVDTTNYVILQGKESRLDQFNYDALTFDEDLNRLT
ASYHSFIASNEIQQSNDLNIESDHDFQSDIELHPEQLRNVLSKAVSPTDSTPPSTHTE
DSKRVSKTNIRAPREVDPNISESNILPSKKRSSTPQISDIESTGSGGMHRLDVPLLAP
MSQSNTHESSHASKSKDFRHSDSYSDNETNHTNVPISSTGGTNNKTVPQTSEQETEKR
IIHRSPSIDTSSSESNSLHHVVPIKTSDTCPKENTEESIIADLPLPDLPPEPPTELSD
SFKELPPINSRQTNSSLGGIGDSNAYTTINSKKRSLEDNETEIKVSRDTWNTKNMRSL
EPPRSKKRIHLIAAVKAVKSIKPIRTTLRYDEAITYNKDIKEKEKYIEAYHKEVNQLL
KMKTWDTDKYYDRKEIDPKRVINSMFIFNRKRDGTHKARFVARGDIQHPDTYDSGMQS
NTVHHYALMTSLSLALDNNYYITQLDISSAYLYADIKEELYIRPPPHLGMNDKLIRLK
KSLYGLKQSGANWYETIKSYLIKQCGMEEVRGWSCVFENSQVTICLFVDDMVLFSKNL
NSNKRIIDKLKMQYDTKIINLGESDEEIQYDILGLEIKYQRGKYMKLGMENSLTEKIP
KLNVPLNPKGRKLSAPGQPGLYIDQQELELEEDDYKMKVHEMQKLIGLASYVGYKFRF
DLLYYINTLAQHILFPSKQVLDMTYELIQFIWNTRDKQLIWHKSKPVKPTNKLVVISD
ASYGNQPYYKSQIGNIYLLNGKVIGGKSTKASLTCTSTTEAEIHAISESVPLLNNLSY
LIQELDKKPITKGLLTDSKSTISIIISNNEEKFRNRFFGTKAMRLRDEVSGNHLHVCY
IETKKNIADVMTKPLPIKTFKLLTNKWIH"
gene complement(361305..362627)
/locus_tag="YMR046C"
/db_xref="GeneID:855063"
mRNA complement(<361305..>362627)
/locus_tag="YMR046C"
/transcript_id="NM_001182543.1"
/db_xref="GI:296147165"
/db_xref="GeneID:855063"
CDS complement(361305..362627)
/locus_tag="YMR046C"
/note="Retrotransposon TYA Gag gene co-transcribed with
TYB Pol; translated as TYA or TYA-TYB polyprotein; Gag is
a nucleocapsid protein that is the structural constituent
of virus-like particles (VLPs); similar to retroviral Gag"
/codon_start=1
/product="gag protein"
/protein_id="NP_013760.1"
/db_xref="GI:6323689"
/db_xref="SGD:S000004649"
/db_xref="GeneID:855063"
/translation="MESQQLSQHSPISHGSACASVTSKEVQTTQDPLDISASKTEECE
KVSTQANSQQPTTPLSSAVPENHHHASPQAAQVPLPQNGPYPQQRMMNTQQANISGWP
VYGHPSLMPYPPYQMSPMYAPPGAQSQFTQYPQYVGTHLNTPSPESGNSFPDSSSAKS
NMTSTNQHVRPPPILTSPNDFLNWVKIYIKFLQNSNLGDIIPTATRKAVRQMTDDELT
FLCHTFQLFAPSQFLPPWVKDILSVDYTDIMKILSKSINKMQSDTQEVNDITTLATLH
YNGSTPADAFEAEVTNILDRLNNNGIPINNKVACQFIMRGLSGEYKFLRYARHRCIHM
TVADLFSDIHSMYEEQQESKRNKSTHRRSPSDEKKDSRTYTNTTKPKSITRNSQKPNN
SQSRTARAHNVSTFNNSPGPDNDLIRGSTTEPIQLKNTHDLHLRPGTY"
LTR complement(362587..362918)
/note="Ty1 LTR"
/db_xref="SGD:S000007110"
gene 363064..363135
/locus_tag="tH(GUG)M"
/db_xref="GeneID:855065"
tRNA 363064..363135
/locus_tag="tH(GUG)M"
/product="tRNA-His"
/note="Histidine tRNA (tRNA-His), predicted by tRNAscan-SE
analysis"
/db_xref="SGD:S000006599"
/db_xref="GeneID:855065"
gene complement(363364..366705)
/gene="NUP116"
/locus_tag="YMR047C"
/gene_synonym="NSP116"
/db_xref="GeneID:855066"
mRNA complement(363364..366705)
/gene="NUP116"
/locus_tag="YMR047C"
/gene_synonym="NSP116"
/product="Nup116p"
/transcript_id="NM_001182544.1"
/db_xref="GI:296147166"
/db_xref="GeneID:855066"
CDS complement(363364..366705)
/gene="NUP116"
/locus_tag="YMR047C"
/gene_synonym="NSP116"
/note="FG-nucleoporin component of central core of the
nuclear pore complex (NPC); contributes directly to
nucleocytoplasmic transport and maintenance of the NPC
permeability barrier; forms a stable association with
Nup82p, Gle2p and two other FG-nucleoporins (Nsp1p and
Nup159p)"
/codon_start=1
/product="Nup116p"
/protein_id="NP_013762.1"
/db_xref="GI:6323691"
/db_xref="SGD:S000004650"
/db_xref="GeneID:855066"
/translation="MFGVSRGAFPSATTQPFGSTGSTFGGQQQQQQPVANTSAFGLSQ
QTNTTQAPAFGNFGNQTSNSPFGMSGSTTANGTPFGQSQLTNNNASGSIFGGMGNNTA
LSAGSASVVPNSTAGTSIKPFTTFEEKDPTTGVINVFQSITCMPEYRNFSFEELRFQD
YQAGRKFGTSQNGTGTTFNNPQGTTNTGFGIMGNNNSTTSATTGGLFGQKPATGMFGT
GTGSGGGFGSGATNSTGLFGSSTNLSGNSAFGANKPATSGGLFGNTTNNPTNGTNNTG
LFGQQNSNTNGGLFGQQQNSFGANNVSNGGAFGQVNRGAFPQQQTQQGSGGIFGQSNA
NANGGAFGQQQGTGALFGAKPASGGLFGQSAGSKAFGMNTNPTGTTGGLFGQTNQQQS
GGGLFGQQQNSNAGGLFGQNNQSQNQSGLFGQQNSSNAFGQPQQQGGLFGSKPAGGLF
GQQQGASTFASGNAQNNSIFGQNNQQQQSTGGLFGQQNNQSQSQPGGLFGQTNQNNNQ
PFGQNGLQQPQQNNSLFGAKPTGFGNTSLFSNSTTNQSNGISGNNLQQQSGGLFQNKQ
QPASGGLFGSKPSNTVGGGLFGNNQVANQNNPASTSGGLFGSKPATGSLFGGTNSTAP
NASSGGIFGSNNASNTAATTNSTGLFGNKPVGAGASTSAGGLFGNNNNSSLNNSNGST
GLFGSNNTSQSTNAGGLFQNNTSTNTSGGGLFSQPSQSMAQSQNALQQQQQQQRLQIQ
NNNPYGTNELFSKATVTNTVSYPIQPSATKIKADERKKASLTNAYKMIPKTLFTAKLK
TNNSVMDKAQIKVDPKLSISIDKKNNQIAISNQQEENLDESILKASELLFNPDKRSFK
NLINNRKMLIASEEKNNGSQNNDMNFKSKSEEQETILGKPKMDEKETANGGERMVLSS
KNDGEDSATKHHSRNMDEENKENVADLQKQEYSEDDKKAVFADVAEKDASFINENYYI
SPSLDTLSSYSLLQLRKVPHLVVGHKSYGKIEFLEPVDLAGIPLTSLGGVIITFEPKT
CIIYANLPNRPKRGEGINVRARITCFNCYPVDKSTRKPIKDPNHQLVKRHIERLKKNP
NSKFESYDADSGTYVFIVNHAAEQT"
gene 366981..367934
/gene="CSM3"
/locus_tag="YMR048W"
/db_xref="GeneID:855067"
mRNA 366981..367934
/gene="CSM3"
/locus_tag="YMR048W"
/product="Csm3p"
/transcript_id="NM_001182545.1"
/db_xref="GI:296147167"
/db_xref="GeneID:855067"
CDS 366981..367934
/gene="CSM3"
/locus_tag="YMR048W"
/note="Replication fork associated factor; required for
stable replication fork pausing; component of the DNA
replication checkpoint pathway; required for accurate
chromosome segregation during meiosis; forms nuclear foci
upon DNA replication stress"
/codon_start=1
/product="Csm3p"
/protein_id="NP_013763.1"
/db_xref="GI:6323692"
/db_xref="SGD:S000004651"
/db_xref="GeneID:855067"
/translation="MDQDFDSLLLGFNDSDSVQKDPTVPNGLDGSVVDPTIADPTAIT
ARKRRPQVKLTAEKLLSDKGLPYVLKNAHKRIRISSKKNSYDNLSNIIQFYQLWAHEL
FPKAKFKDFMKICQTVGKTDPVLREYRVSLFRDEMGMSFDVGTRETGQDLERQSPMVE
EHVTSAEERPIVADSFAQDKRNVNNVDYDNDEDDDIYHLSYRNRRGRVLDERGNNETV
LNNVVPPKEDLDALLKTFRVQGPVGLEENEKKLLLGWLDAHRKMEKGSMTEEDVQLIQ
SLEEWEMNDIEGQHTHYDLLPGGDEFGVDQDELDAMKEMGF"
gene complement(368094..370517)
/gene="ERB1"
/locus_tag="YMR049C"
/db_xref="GeneID:855068"
mRNA complement(368094..370517)
/gene="ERB1"
/locus_tag="YMR049C"
/product="Erb1p"
/transcript_id="NM_001182546.1"
/db_xref="GI:296147168"
/db_xref="GeneID:855068"
CDS complement(368094..370517)
/gene="ERB1"
/locus_tag="YMR049C"
/note="Constituent of 66S pre-ribosomal particles, forms a
complex with Nop7p and Ytm1p that is required for
maturation of the large ribosomal subunit; required for
maturation of the 25S and 5.8S ribosomal RNAs; homologous
to mammalian Bop1"
/codon_start=1
/product="Erb1p"
/protein_id="NP_013764.1"
/db_xref="GI:6323693"
/db_xref="SGD:S000004652"
/db_xref="GeneID:855068"
/translation="MMAKNNKTTEAKMSKKRAASEESDVEEDEDKLLSVDGLIDAEAS
ESDEDDDEYESAVEEKESSSDKEAQDDSDDDSDAELNKLLAEEEGDGEEDYDSSEFSD
DTTSLTDRLSGVKLQTIVDPNIYSKYADGSDRIIKPEINPVYDSDDSDAETQNTIGNI
PLSAYDEMPHIGYDINGKRIMRPAKGSALDQLLDSIELPEGWTGLLDKNSGSSLNLTK
EELELISKIQRNEQTDDSINPYEPLIDWFTRHEEVMPLTAVPEPKRRFVPSKNEAKRV
MKIVRAIREGRIIPPKKLKEMKEKEKIENYQYDLWGDSTETNDHVMHLRAPKLPPPTN
EESYNPPEEYLLSPEEKEAWENTEYSERERNFIPQKYSALRKVPGYGESIRERFERSL
DLYLAPRVRKNKLNIDPNSLIPELPSPKDLRPFPIRCSTIYAGHKGKVRTLSIDPSGL
WLATGSDDGTVRVWEILTGREVYRTTLIDDEENPDYHIECIEWNPDANNGILAVAVGE
NIHLIVPPIFGYDIENNGKTKIEDGFGYDTFGTVKKSNLEVNENGDGDEDGENESAKN
AVKKQVAQWNKPSQKQLEKDICITISCKKTVKKLSWHRKGDYFVTVQPDSGNTSVLIH
QVSKHLTQSPFKKSKGIIMDAKFHPFKPQLFVCSQRYVRIYDLSQQILVKKLLPGARW
LSKIDIHPRGDNLIASSFDKRVLWHDLDLASTPYKTLRYHEKAVRSVNFHKKLPLFSS
AADDGTIHVFHATVYDDMMKNPMIVPLKKLTGHKVINSLGVLDAIWHPREAWLFSAGA
DNTARLWTT"
rep_origin 370978..371222
/note="ARS1312;
Autonomously Replicating Sequence"
/db_xref="SGD:S000118371"
gene complement(372445..372518)
/locus_tag="tV(AAC)M1"
/db_xref="GeneID:855069"
tRNA complement(372445..372518)
/locus_tag="tV(AAC)M1"
/product="tRNA-Val"
/note="Valine tRNA (tRNA-Val), predicted by tRNAscan-SE
analysis"
/db_xref="SGD:S000006763"
/db_xref="GeneID:855069"
mobile_element complement(372697..378622)
/note="YMRCTy1-4; Ty1 element, LTR retrotransposon of the
Copia (Pseudoviridae) group; contains co-transcribed genes
TYA Gag and TYB Pol, encoding proteins involved in
structure and function of virus-like particles, flanked by
two direct repeats"
/mobile_element_type="retrotransposon:YMRCTy1-4"
/db_xref="SGD:S000007120"
LTR complement(372697..373034)
/note="Ty1 LTR"
/db_xref="SGD:S000007111"
gene complement(373057..378325)
/locus_tag="YMR050C"
/db_xref="GeneID:855070"
mRNA complement(join(<373057..377019,377021..>378325))
/locus_tag="YMR050C"
/transcript_id="NM_001182547.1"
/db_xref="GI:296147169"
/db_xref="GeneID:855070"
CDS complement(join(373057..377019,377021..378325))
/locus_tag="YMR050C"
/EC_number="2.7.7.49"
/EC_number="3.4.23.-"
/EC_number="3.1.26.4"
/EC_number="2.7.7.7"
/ribosomal_slippage
/note="Retrotransposon TYA Gag and TYB Pol genes;
transcribed/translated as one unit; polyprotein is
processed to make a nucleocapsid-like protein (Gag),
reverse transcriptase (RT), protease (PR), and integrase
(IN); similar to retroviral genes"
/codon_start=1
/product="gag-pol fusion protein"
/protein_id="NP_013765.1"
/db_xref="GI:6323694"
/db_xref="SGD:S000004653"
/db_xref="GeneID:855070"
/translation="MESQQLSNYPHISHGSACASVTSKEVHTNQDPLDVSASKIQEYD
KASTKANSQQTTTPASSAVPENPHHASPQPASVPPPQNGPYPQQCMMTQNQANPSGWS
FYGHPSMIPYTPYQMSPMYFPPGPQSQFPQYPSSVGTPLSTPSPESGNTFTDSSSADS
DMTSTKKYVRPPPMLTSPNDFPNWVKTYIKFLQNSNLGGIIPTVNGKPVRQITDDELT
FLYNTFQIFAPSQFLPTWVKDILSVDYTDIMKILSKSIEKMQSDTQEANDIVTLANLQ
YNGSTPADAFETKVTNIIDRLNNNGIHINNKVACQLIMRGLSGEYKFLRYTRHRHLNM
TVAELFLDIHAIYEEQQGSRNSKPNYRRNPSDEKNDSRSYTNTTKPKVIARNPQKTNN
SKSKTARAHNVSTSNNSPSTDNDSISKSTTEPIQLNNKHDLHLGQKLTESTVNHTNHS
DDELPGHLLLDSGASRTLIRSAHHIHSASSNPDINVVDAQKRNIPINAIGDLQFHFQD
NTKTSIKVLHTPNIAYDLLSLNELAAVDITACFTKNVLERSDGTVLAPIVKYGDFYWV
SKKYLLPSNISVPTINNVHTSESTRKYPYPFIHRMLAHANAQTIRYSLKNNTITYFNE
SDVDWSSAIDYQCPDCLIGKSTKHRHIKGSRLKYQNSYEPFQYLHTDIFGPVHNLPKS
APSYFISFTDETTKFRWVYPLHDRREDSILDVFTTILAFIKNQFQASVLVIQMDRGSE
YTNRTLHKFLEKNGITPCYTTTADSRAHGVAERLNRTLLDDCRTQLQCSGLPNHLWFS
AIEFSTIVRNSLASPKSKKSARQHAGLAGLDISTLLPFGQPVIVNDHNPNSKIHPRGI
PGYALHPSRNSYGYIIYLPSLKKTVDTTNYVILQGKESRLDQFNYDALTFDEDLNRLT
ASYQSFIASNEIQQSDDLNIESDHDFQSDIELHPEQPRNVLSKAVSPTDSTPPSTHTE
DSKRVSKTNIRAPREVDPNISESNILPSKKRSSTPQISNIESTGSGGMHKLNVPLLAP
MSQSNTHESSHASKSKDFRHSDSYSENETNHTNVPISSTGGTNNKTVPQISDQETEKR
IIHRSPSIDASPPENNSSHNIVPIKTPTTVSEQNTEESIIADLPLPDLPPESPTEFPD
PFKELPPINSRQTNSSLGGIGDSNAYTTINSKKRSLEDNETEIKVSRDTWNTKNMRSL
EPPRSKKRIHLIAAVKAVKSIKPIRTTLRYDEAITYNKDIKEKEKYIQAYHKEVNQLL
KMKTWDTDRYYDRKEIDPKRVINSMFIFNRKRDGTHKARFVARGDIQHPDTYDPGMQS
NTVHHYALMTSLSLALDNNYYITQLDISSAYLYADIKEELYIRPPPHLGMNDKLIRLK
KSLYGLKQSGANWYETIKSYLIKQCGMEEVRGWSCVFKNSQVTICLFVDDMILFSKDL
NANKKIITTLKKQYDTKIINLGESDNEIQYDILGLEIKYQRGKYMKLGMENSLTEKIP
KLNVPLNPKGRKLSAPGQPGLYIDQQELELEEDDYKMKVHEMQKLIGLASYVGYKFRF
DLLYYINTLAQHILFPSKQVLDMTYELIQFIWNTRDKQLIWHKSKPVKPTNKLVVISD
ASYGNQPYYKSQIGNIYLLNGKVIGGKSTKASLTCTSTTEAEIHAISESVPLLNNLSH
LVQELNKKPITKGLLTDSKSTISIIISNNEEKFRNRFFGTKAMRLRDEVSGNHLHVCY
IETKKNIADVMTKPLPIKTFKLLTNKWIH"
gene complement(377003..378325)
/locus_tag="YMR051C"
/db_xref="GeneID:855071"
mRNA complement(<377003..>378325)
/locus_tag="YMR051C"
/transcript_id="NM_001182548.1"
/db_xref="GI:296147170"
/db_xref="GeneID:855071"
CDS complement(377003..378325)
/locus_tag="YMR051C"
/note="Retrotransposon TYA Gag gene co-transcribed with
TYB Pol; translated as TYA or TYA-TYB polyprotein; Gag is
a nucleocapsid protein that is the structural constituent
of virus-like particles (VLPs); similar to retroviral Gag"
/codon_start=1
/product="gag protein"
/protein_id="NP_013766.1"
/db_xref="GI:6323695"
/db_xref="SGD:S000004654"
/db_xref="GeneID:855071"
/translation="MESQQLSNYPHISHGSACASVTSKEVHTNQDPLDVSASKIQEYD
KASTKANSQQTTTPASSAVPENPHHASPQPASVPPPQNGPYPQQCMMTQNQANPSGWS
FYGHPSMIPYTPYQMSPMYFPPGPQSQFPQYPSSVGTPLSTPSPESGNTFTDSSSADS
DMTSTKKYVRPPPMLTSPNDFPNWVKTYIKFLQNSNLGGIIPTVNGKPVRQITDDELT
FLYNTFQIFAPSQFLPTWVKDILSVDYTDIMKILSKSIEKMQSDTQEANDIVTLANLQ
YNGSTPADAFETKVTNIIDRLNNNGIHINNKVACQLIMRGLSGEYKFLRYTRHRHLNM
TVAELFLDIHAIYEEQQGSRNSKPNYRRNPSDEKNDSRSYTNTTKPKVIARNPQKTNN
SKSKTARAHNVSTSNNSPSTDNDSISKSTTEPIQLNNKHDLHLRPETY"
LTR complement(378285..378622)
/note="Ty1 LTR"
/db_xref="SGD:S000007112"
LTR complement(378727..379061)
/note="Ty1 LTR"
/db_xref="SGD:S000007113"
LTR 379072..379198
/note="Ty1 LTR"
/db_xref="SGD:S000007121"
gene complement(379303..379408)
/locus_tag="tW(CCA)M"
/db_xref="GeneID:855072"
tRNA complement(join(379303..379338,379373..379408))
/locus_tag="tW(CCA)M"
/product="tRNA-Trp"
/note="Tryptophan tRNA (tRNA-Trp), predicted by
tRNAscan-SE analysis"
/db_xref="SGD:S000006775"
/db_xref="GeneID:855072"
gene 379586..380200
/gene="FAR3"
/locus_tag="YMR052W"
/db_xref="GeneID:855073"
mRNA 379586..380200
/gene="FAR3"
/locus_tag="YMR052W"
/product="Far3p"
/transcript_id="NM_001182550.1"
/db_xref="GI:296147171"
/db_xref="GeneID:855073"
CDS 379586..380200
/gene="FAR3"
/locus_tag="YMR052W"
/note="hypothetical protein; involved in recovery from
cell cycle arrest in response to pheromone, in a
Far1p-independent pathway; interacts with Far7p, Far8p,
Far9p, Far10p, and Far11p; localizes to the endoplasmic
reticulum; protein abundance increases in response to DNA
replication stress"
/codon_start=1
/product="Far3p"
/protein_id="NP_013767.1"
/db_xref="GI:6323696"
/db_xref="SGD:S000004656"
/db_xref="GeneID:855073"
/translation="MNSGGSDSFDYLLQLTKALSAECRANRQETDRIELLLKRLAKQS
GISYDNLSKNIIPDSWKDNASQKASPPTEAQKLISENFKLIYEIEKQEYFNTKAVALI
NNINEHFSYIKNFIDEQNAIRERNIATFSSEKLDERNKSLQQNYESLKTENEETKKKL
HSIIKQFEKLLKEVDWDRISKDSRDYSRFKKQLEYLQDTYQVLK"
gene complement(380346..382898)
/gene="STB2"
/locus_tag="YMR053C"
/db_xref="GeneID:855075"
mRNA complement(380346..382898)
/gene="STB2"
/locus_tag="YMR053C"
/product="Stb2p"
/transcript_id="NM_001182551.1"
/db_xref="GI:296147172"
/db_xref="GeneID:855075"
CDS complement(380346..382898)
/gene="STB2"
/locus_tag="YMR053C"
/note="Protein that interacts with Sin3p in a two-hybrid
assay and is part of a large protein complex with Sin3p
and Stb1p"
/codon_start=1
/product="Stb2p"
/protein_id="NP_013769.1"
/db_xref="GI:6323698"
/db_xref="SGD:S000004657"
/db_xref="GeneID:855075"
/translation="MVMADTIATGDKTSQFDGKHMQDLERIYSTRDTLDDNFFGERGQ
KDANGDYYDELNNEETNYSGSSYYGHSDDSEVVGLIKNDTVSQLPPLDSFIFPDSRAL
FLLDLGNYADLTYEEIIVHGFEIYIVEQWVACRNLSTLITSYTGNSQDTISGVRVVLP
KDTSMWPGRFRLYFEELMEFARPKFTPKGTLFITNLSGVSFGLNLLHVECGDLRTIWK
DFEVNFDLKNLHCGGRSANLLCPPTMASLDKFSQLFKIPTNGFIAQYPQMIQQQQPRL
PEEEYKTVGNSKCRNTDSKSPVVEMVTLIQISLSYFNLLSKNYQTDGLLCEDTKRAID
EWWETYGKLYLGTEKPRNECTLGPTTVAGLISLILCCYFKLMIENCISSKDPFDEAGF
FQGIYNFQKKHGLNKRKSRVYLDPRTLEKLFEVTAKVSSKDIFKLKKMVTSTVQDIIG
KGNPINLSHKILTTDLDTLIHNIHGGSVGLLWKGKGHPRKCCTDISNEEFLKFNYQRG
DPDGQIREREMLLEKFRLERIAYAQKHASKKVSSSSLDTSEDIGRTNAMPSSATVSSM
FPNYDNTKYAYNFGINKLYQGEYYRRNSFPYCKDRTHDNIYEDLSELKEKSSRLYRCN
SSSAVQNIVEKWDLPFDPSVVRIARDLLRMKYDIQAQQHIQEMDEHYMGKLNKEGTVG
QYSKFNERYKRLQELYKKYSDGAKVFEGRFEDIDNKQQLLLHEMQELNSLSSRLKYDM
RILEVRVRDIESSVAQFDSKLIGLKSSLQGQGKTGICSAIDPKSDKDEYDRCVNDLMT
TNNPTYEALCLKMLSRRYFKDLKNDTVGWFRWLFGNNSLHNNASEDDRGIRV"
gene 383303..385975
/gene="STV1"
/locus_tag="YMR054W"
/db_xref="GeneID:855076"
mRNA 383303..385975
/gene="STV1"
/locus_tag="YMR054W"
/product="Stv1p"
/transcript_id="NM_001182552.1"
/db_xref="GI:296147173"
/db_xref="GeneID:855076"
CDS 383303..385975
/gene="STV1"
/locus_tag="YMR054W"
/EC_number="3.6.3.14"
/note="Subunit a of the vacuolar-ATPase V0 domain, one of
two isoforms (Stv1p and Vph1p); Stv1p is located in
V-ATPase complexes of the Golgi and endosomes while Vph1p
is located in V-ATPase complexes of the vacuole"
/codon_start=1
/product="Stv1p"
/protein_id="NP_013770.1"
/db_xref="GI:6323699"
/db_xref="SGD:S000004658"
/db_xref="GeneID:855076"
/translation="MNQEEAIFRSADMTYVQLYIPLEVIREVTFLLGKMSVFMVMDLN
KDLTAFQRGYVNQLRRFDEVERMVGFLNEVVEKHAAETWKYILHIDDEGNDIAQPDMA
DLINTMEPLSLENVNDMVKEITDCESRARQLDESLDSLRSKLNDLLEQRQVIFECSKF
IEVNPGIAGRATNPEIEQEERDVDEFRMTPDDISETLSDAFSFDDETPQDRGALGNDL
TRNQSVEDLSFLEQGYQHRYMITGSIRRTKVDILNRILWRLLRGNLIFQNFPIEEPLL
EGKEKVEKDCFIIFTHGETLLKKVKRVIDSLNGKIVSLNTRSSELVDTLNRQIDDLQR
ILDTTEQTLHTELLVIHDQLPVWSAMTKREKYVYTTLNKFQQESQGLIAEGWVPSTEL
IHLQDSLKDYIETLGSEYSTVFNVILTNKLPPTYHRTNKFTQAFQSIVDAYGIATYKE
INAGLATVVTFPFMFAIMFGDMGHGFILFLMALFLVLNERKFGAMHRDEIFDMAFTGR
YVLLLMGAFSVYTGLLYNDIFSKSMTIFKSGWQWPSTFRKGESIEAKKTGVYPFGLDF
AWHGTDNGLLFSNSYKMKLSILMGYAHMTYSFMFSYINYRAKNSKVDIIGNFIPGLVF
MQSIFGYLSWAIVYKWSKDWIKDDKPAPGLLNMLINMFLAPGTIDDQLYSGQAKLQVV
LLLAALVCVPWLLLYKPLTLRRLNKNGGGGRPHGYQSVGNIEHEEQIAQQRHSAEGFQ
GMIISDVASVADSINESVGGGEQGPFNFGDVMIHQVIHTIEFCLNCISHTASYLRLWA
LSLAHAQLSSVLWDMTISNAFSSKNSGSPLAVMKVVFLFAMWFVLTVCILVFMEGTSA
MLHALRLHWVEAMSKFFEGEGYAYEPFSFRAIIE"
gene complement(386101..387021)
/gene="BUB2"
/locus_tag="YMR055C"
/gene_synonym="PAC7"
/db_xref="GeneID:855077"
mRNA complement(386101..387021)
/gene="BUB2"
/locus_tag="YMR055C"
/gene_synonym="PAC7"
/product="Bub2p"
/transcript_id="NM_001182553.1"
/db_xref="GI:296147174"
/db_xref="GeneID:855077"
CDS complement(386101..387021)
/gene="BUB2"
/locus_tag="YMR055C"
/gene_synonym="PAC7"
/note="Mitotic exit network regulator, forms
GTPase-activating Bfa1p-Bub2p complex that binds Tem1p and
spindle pole bodies, blocks cell cycle progression before
anaphase in response to spindle and kinetochore damage"
/codon_start=1
/product="Bub2p"
/protein_id="NP_013771.1"
/db_xref="GI:6323700"
/db_xref="SGD:S000004659"
/db_xref="GeneID:855077"
/translation="MTSIEDLISNPPLLLHSSLSQLRYLILSEGLPISEDKQQQRTRC
YVWTVLSQTSMEASTQRYLALLKLGPPSTTIYQKIKNDTSRTFQTDPNFRNRVSEDAL
IRCLSCFAWQTQQRRQKTRFGRIPVSTYVQGMNVLLAPLLYSCPSEPMAYQLFTKLCY
EMIPTYLTKNLNGAQNGAKLLDISLRIIDPKLSKFLSDNLLTAEIYGMPSILTLSSCN
KPLDQVIKLWDFMFAYGFHMNILFVVAFLVKMRSKVFKSDSPVNLLRQFPDFDADEII
RLGVGFIAKIPAQIYDLLVDHLTDPDIYIP"
gene complement(387315..388244)
/gene="AAC1"
/locus_tag="YMR056C"
/db_xref="GeneID:855078"
mRNA complement(387315..388244)
/gene="AAC1"
/locus_tag="YMR056C"
/product="Aac1p"
/transcript_id="NM_001182554.1"
/db_xref="GI:296147175"
/db_xref="GeneID:855078"
CDS complement(387315..388244)
/gene="AAC1"
/locus_tag="YMR056C"
/note="Mitochondrial inner membrane ADP/ATP translocator;
exchanges cytosolic ADP for mitochondrially synthesized
ATP; phosphorylated; Aac1p is a minor isoform while Pet9p
is the major ADP/ATP translocator; relocalizes from
mitochondrion to cytoplasm upon DNA replication stress"
/codon_start=1
/product="Aac1p"
/protein_id="NP_013772.1"
/db_xref="GI:6323701"
/db_xref="SGD:S000004660"
/db_xref="GeneID:855078"
/translation="MSHTETQTQQSHFGVDFLMGGVSAAIAKTGAAPIERVKLLMQNQ
EEMLKQGSLDTRYKGILDCFKRTATHEGIVSFWRGNTANVLRYFPTQALNFAFKDKIK
SLLSYDRERDGYAKWFAGNLFSGGAAGGLSLLFVYSLDYARTRLAADARGSKSTSQRQ
FNGLLDVYKKTLKTDGLLGLYRGFVPSVLGIIVYRGLYFGLYDSFKPVLLTGALEGSF
VASFLLGWVITMGASTASYPLDTVRRRMMMTSGQTIKYDGALDCLRKIVQKEGAYSLF
KGCGANIFRGVAAAGVISLYDQLQLIMFGKKFK"
gene 388822..390732
/gene="FET3"
/locus_tag="YMR058W"
/db_xref="GeneID:855080"
mRNA 388822..390732
/gene="FET3"
/locus_tag="YMR058W"
/product="Fet3p"
/transcript_id="NM_001182556.1"
/db_xref="GI:296147176"
/db_xref="GeneID:855080"
CDS 388822..390732
/gene="FET3"
/locus_tag="YMR058W"
/EC_number="1.-.-.-"
/note="Ferro-O2-oxidoreductase; required for high-affinity
iron uptake and involved in mediating resistance to copper
ion toxicity, belongs to class of integral membrane
multicopper oxidases; protein abundance increases in
response to DNA replication stress"
/codon_start=1
/product="Fet3p"
/protein_id="NP_013774.1"
/db_xref="GI:6323703"
/db_xref="SGD:S000004662"
/db_xref="GeneID:855080"
/translation="MTNALLSIAVLLFSMLSLAQAETHTFNWTTGWDYRNVDGLKSRP
VITCNGQFPWPDITVNKGDRVQIYLTNGMNNTNTSMHFHGLFQNGTASMDGVPFLTQC
PIAPGSTMLYNFTVDYNVGTYWYHSHTDGQYEDGMKGLFIIKDDSFPYDYDEELSLSL
SEWYHDLVTDLTKSFMSVYNPTGAEPIPQNLIVNNTMNLTWEVQPDTTYLLRIVNVGG
FVSQYFWIEDHEMTVVEIDGITTEKNVTDMLYITVAQRYTVLVHTKNDTDKNFAIMQK
FDDTMLDVIPSDLQLNATSYMVYNKTAALPTQNYVDSIDNFLDDFYLQPYEKEAIYGE
PDHVITVDVVMDNLKNGVNYAFFNNITYTAPKVPTLMTVLSSGDQANNSEIYGSNTHT
FILEKDEIVEIVLNNQDTGTHPFHLHGHAFQTIQRDRTYDDALGEVPHSFDPDNHPAF
PEYPMRRDTLYVRPQSNFVIRFKADNPGVWFFHCHIEWHLLQGLGLVLVEDPFGIQDA
HSQQLSENHLEVCQSCSVATEGNAAANTLDLTDLTGENVQHAFIPTGFTKKGIIAMTF
SCFAGILGIITIAIYGMMDMEDATEKVIRDLHVDPEVLLNEVDENEERQVNEDRHSTE
KHQFLTKAKRFF"
gene 391099..391485
/gene="SEN15"
/locus_tag="YMR059W"
/db_xref="GeneID:855081"
mRNA 391099..391485
/gene="SEN15"
/locus_tag="YMR059W"
/product="Sen15p"
/transcript_id="NM_001182557.1"
/db_xref="GI:296147177"
/db_xref="GeneID:855081"
CDS 391099..391485
/gene="SEN15"
/locus_tag="YMR059W"
/note="Subunit of the tRNA splicing endonuclease, which is
composed of Sen2p, Sen15p, Sen34p, and Sen54p"
/codon_start=1
/product="Sen15p"
/protein_id="NP_013775.2"
/db_xref="GI:99030929"
/db_xref="SGD:S000004663"
/db_xref="GeneID:855081"
/translation="MATTDIISLVKNNLLYFQMWTEVEILQDDLSWKGNSLRLLRGRP
PHKLSNDVDTEHENSLSSPRPLEFILPINMSQYKENFLTLECLSQTFTHLCSPSTERI
LLAIINDDGTIVYYFVYKGVRKPKRN"
gene complement(391532..392515)
/gene="SAM37"
/locus_tag="YMR060C"
/gene_synonym="MAS37; PET3027; TOM37"
/db_xref="GeneID:855082"
mRNA complement(391532..392515)
/gene="SAM37"
/locus_tag="YMR060C"
/gene_synonym="MAS37; PET3027; TOM37"
/product="Sam37p"
/transcript_id="NM_001182558.1"
/db_xref="GI:296147178"
/db_xref="GeneID:855082"
CDS complement(391532..392515)
/gene="SAM37"
/locus_tag="YMR060C"
/gene_synonym="MAS37; PET3027; TOM37"
/note="Component of the Sorting and Assembly Machinery
(SAM or TOB complex) of the mitochondrial outer membrane,
which binds precursors of beta-barrel proteins and
facilitates their outer membrane insertion; contributes to
SAM complex stability"
/codon_start=1
/product="Sam37p"
/protein_id="NP_013776.1"
/db_xref="GI:6323705"
/db_xref="SGD:S000004664"
/db_xref="GeneID:855082"
/translation="MVKGSVHLWGKDGKASLISVDSIALVWFIKLCTSEEAKSMVAGL
QIVFSNNTDLSSDGKLPVLILDNGTKVSGYVNIVQFLHKNICTSKYEKGTDYEEDLAI
VRKKDRLLEYSLLNYVDVEISRLTDYQLFLNTKNYNEYTKKLFSKLLYFPMWYNTPLQ
LRSQARENCEEIIGSLTLEDDEEFVESKAMESASQLAQSKTFKIAHKNKIKGKQELQQ
VKYNLQFDNRLQSCVSNWLAARKKLDDSVILSSDLLFLANLYVQLGLPDGNRIRSKLE
QTFGSELLNSMSNKIDDFVHRPSNNLEQRDPQFREQGNVVMSLYNLACKYI"
gene 392755..394788
/gene="RNA14"
/locus_tag="YMR061W"
/db_xref="GeneID:855083"
mRNA 392755..394788
/gene="RNA14"
/locus_tag="YMR061W"
/product="Rna14p"
/transcript_id="NM_001182559.1"
/db_xref="GI:296147179"
/db_xref="GeneID:855083"
CDS 392755..394788
/gene="RNA14"
/locus_tag="YMR061W"
/note="Component of the cleavage and polyadenylation
factor I (CF I); CF 1, composed of the CF 1A complex
(Rna14p, Rna15p, Clp1p, Pcf11p) and Hrp1, is involved in
cleavage and polyadenylation of mRNA 3' ends; bridges
interaction between Rna15p and Hrp1p in the CF I complex;
mutant displays reduced transcription elongation in the
G-less-based run-on (GLRO) assay; required for gene
looping"
/codon_start=1
/product="Rna14p"
/protein_id="NP_013777.1"
/db_xref="GI:6323706"
/db_xref="SGD:S000004665"
/db_xref="GeneID:855083"
/translation="MSSSTTPDLLYPSADKVAEPSDNIHGDELRLRERIKDNPTNILS
YFQLIQYLETQESYAKVREVYEQFHNTFPFYSPAWTLQLKGELARDEFETVEKILAQC
LSGKLENNDLSLWSTYLDYIRRKNNLITGGQEARAVIVKAFQLVMQKCAIFEPKSSSF
WNEYLNFLEQWKPFNKWEEQQRIDMLREFYKKMLCVPFDNLEKMWNRYTQWEQEINSL
TARKFIGELSAEYMKARSLYQEWLNVTNGLKRASPINLRTANKKNIPQPGTSDSNIQQ
LQIWLNWIKWERENKLMLSEDMLSQRISYVYKQGIQYMIFSAEMWYDYSMYISENSDR
QNILYTALLANPDSPSLTFKLSECYELDNDSESVSNCFDKCTQTLLSQYKKIASDVNS
GEDNNTEYEQELLYKQREKLTFVFCVYMNTMKRISGLSAARTVFGKCRKLKRILTHDV
YVENAYLEFQNQNDYKTAFKVLELGLKYFQNDGVYINKYLDFLIFLNKDSQIKTLFET
SVEKVQDLTQLKEIYKKMISYESKFGNLNNVYSLEKRFFERFPQENLIEVFTSRYQIQ
NSNLIKKLELTYMYNEEEDSYFSSGNGDGHHGSYNMSSSDRKRLMEETGNNGNFSNKK
FKRDSELPTEVLDLLSVIPKRQYFNTNLLDAQKLVNFLNDQVEIPTVESTKSG"
gene complement(395054..396379)
/gene="ARG7"
/locus_tag="YMR062C"
/gene_synonym="ECM40"
/db_xref="GeneID:855084"
mRNA complement(395054..396379)
/gene="ARG7"
/locus_tag="YMR062C"
/gene_synonym="ECM40"
/product="glutamate N-acetyltransferase"
/transcript_id="NM_001182560.1"
/db_xref="GI:296147180"
/db_xref="GeneID:855084"
CDS complement(395054..396379)
/gene="ARG7"
/locus_tag="YMR062C"
/gene_synonym="ECM40"
/EC_number="2.3.1.1"
/EC_number="2.3.1.35"
/note="Mitochondrial ornithine acetyltransferase,
catalyzes the fifth step in arginine biosynthesis; also
possesses acetylglutamate synthase activity, regenerates
acetylglutamate while forming ornithine"
/codon_start=1
/product="glutamate N-acetyltransferase"
/protein_id="NP_013778.1"
/db_xref="GI:6323707"
/db_xref="SGD:S000004666"
/db_xref="GeneID:855084"
/translation="MRISSTLLQRSKQLIDKYALYVPKTGSFPKGFEVGYTASGVKKN
GSLDLGVILNTNKSRPSTAAAVFTTNKFKAAPVLTSKKVLETARGKNINAIVVNSGCA
NSVTGDLGMKDAQVMIDLVNDKIGQKNSTLVMSTGVIGQRLQMDKISTGINKIFGEEK
FGSDFNSWLNVAKSICTTDTFPKLVTSRFKLPSGTEYTLTGMAKGAGMICPNMATLLG
FIVTDLPIESKALQKMLTFATTRSFNCISVDGDMSTNDTICMLANGAIDTKEINEDSK
DFEQVKLQVTEFAQRLAQLVVRDGEGSTKFVTVNVKNALHFEDAKIIAESISNSMLVK
TALYGQDANWGRILCAIGYAKLNDLKSLDVNKINVSFIATDNSEPRELKLVANGVPQL
EIDETRASEILALNDLEVSVDLGTGDQAAQFWTCDLSHEYVTINGDYRS"
gene 397077..397796
/gene="RIM9"
/locus_tag="YMR063W"
/db_xref="GeneID:855085"
mRNA 397077..397796
/gene="RIM9"
/locus_tag="YMR063W"
/product="Rim9p"
/transcript_id="NM_001182561.1"
/db_xref="GI:296147181"
/db_xref="GeneID:855085"
CDS 397077..397796
/gene="RIM9"
/locus_tag="YMR063W"
/note="Plasma membrane hypothetical protein; involved in
the proteolytic activation of Rim101p in response to
alkaline pH; interacts with Rim21p and Dfg16p to form a
pH-sensing complex in the Rim101 pathway and is required
to maintain Rim21p levels; has similarity to A. nidulans
PalI"
/codon_start=1
/product="Rim9p"
/protein_id="NP_013779.1"
/db_xref="GI:6323708"
/db_xref="SGD:S000004667"
/db_xref="GeneID:855085"
/translation="MVSMIHIVVFLLAITTMFEILPLITVPVTKYLSLSSFRNHYYGL
FGWCVRGQNQELMCTKMKIGYDSTDVDSSGHVLTLPSNSKVVVSNLLVVHPISLAFTG
TLLILAVIIMVTPLGDSPEMLLFTALFSLPTFMLCLLCFLVDILLFISKLDWPGWLML
AATISVALCCSMLWVMRRVVSVKKYESQQSIAHACSMEQYSISDIYQSKQNGNSSEYE
VAPTHTDSLIAPEVTYRGFIE"
gene 397903..399459
/gene="AEP1"
/locus_tag="YMR064W"
/gene_synonym="NCA1"
/db_xref="GeneID:855086"
mRNA 397903..399459
/gene="AEP1"
/locus_tag="YMR064W"
/gene_synonym="NCA1"
/product="Aep1p"
/transcript_id="NM_001182562.1"
/db_xref="GI:296147182"
/db_xref="GeneID:855086"
CDS 397903..399459
/gene="AEP1"
/locus_tag="YMR064W"
/gene_synonym="NCA1"
/note="Protein required for expression of the
mitochondrial OLI1 gene encoding subunit 9 of F1-F0 ATP
synthase"
/codon_start=1
/product="Aep1p"
/protein_id="NP_013780.1"
/db_xref="GI:6323709"
/db_xref="SGD:S000004668"
/db_xref="GeneID:855086"
/translation="MITTVQEISKWRNLCFIRMQSRKWYPVLKKTPLVADGRKIIKHA
DKVPHPEEIIHPFYQPTAIEQFTACATEYNPSLLDGKKIAPSLIKHPVSLKTILVDSK
LKFDDIRGVNKWLMEFVARRQHQRNIVLTPASKSVRSFHVLHLSSTDIAKLRGLENIL
SEIENTNDLQSRVESVNNELQNIFDRDSKQTRLFCENILAYLIKNYGNSTEKLILLIN
VTEMQLYSRLDQMKAMNIILYNILCKVEANENPPYSPTLVTALENLLAAINNRFFPGR
CENSLHPIVIEQLLSYFIKTGNLNESKNFLGHLIKKGILPEATIINRYLEAIDVHFDK
STKIFDIRSKFAFIADLAPIIENYGTIDLFKFLIPMCRHFDELCSLLNIIRKSNNAKR
AVDSTLPIFIKKVLTFTKDPMINSGNLSTVFNIVSPIYGQNVPSEFVEKFILSFALQG
NYTMMAHMIDTYKIKLSHKYQLQIIRALKNSERNHALKNTGAVGYNKEFKKYFIEKYL
NCTEREALRP"
gene 399702..401216
/gene="KAR5"
/locus_tag="YMR065W"
/gene_synonym="FIG3"
/db_xref="GeneID:855087"
mRNA 399702..401216
/gene="KAR5"
/locus_tag="YMR065W"
/gene_synonym="FIG3"
/product="Kar5p"
/transcript_id="NM_001182563.1"
/db_xref="GI:296147183"
/db_xref="GeneID:855087"
CDS 399702..401216
/gene="KAR5"
/locus_tag="YMR065W"
/gene_synonym="FIG3"
/note="Protein required for nuclear membrane fusion during
karyogamy, localizes to the membrane with a soluble
portion in the endoplasmic reticulum lumen, may form a
complex with Jem1p and Kar2p; expression of the gene is
regulated by pheromone"
/codon_start=1
/product="Kar5p"
/protein_id="NP_013781.1"
/db_xref="GI:6323710"
/db_xref="SGD:S000004669"
/db_xref="GeneID:855087"
/translation="MFEMRYVYLFAICIKFVSSSELGKINNLLQGRLIYTDNSVATNV
LESKFPFLKSTCVKDALKLFLPQCIANGLESIDAETRVETAIKLSICEFQASGLGEIP
ENCMVDDLGSMMDCMFELESSSQWWTTYSGNYQRLSSICYENLLPFEKEQILKLFLNI
TELYDSFGDDVDTKLNHLMFQMEQDSQNFLDDLARMFRNYDNELRNATESNRIILEND
LSFFRNKVNDVLYETSEQLEVQIIEKNSQLMNEVDTVHHIMSDLADELAKNDIKSKIN
DLKDDSLNNLQDLVEMSNDVKEYYSRNNKLVNTELENFSMGLKKQLGGMSKDLSESQM
EAIELLQGFNSILHDSLLPSMTDEIVPEMTNFKNTLLQEWTAITSTLNGDFALWNEEI
FSTFNDISEKLNGTKKKLDDIEIRVSLVHKNVMTMMRVLDFMWKTSKMIIRCGYLAVK
NKYYWLLCSVVWIWSKYRTSRVNVKMIPIKRYYQWAALLLSIYLGAKTGSLIDF"
gene 401541..404237
/gene="SOV1"
/locus_tag="YMR066W"
/db_xref="GeneID:855088"
mRNA 401541..404237
/gene="SOV1"
/locus_tag="YMR066W"
/product="Sov1p"
/transcript_id="NM_001182564.1"
/db_xref="GI:296147184"
/db_xref="GeneID:855088"
CDS 401541..404237
/gene="SOV1"
/locus_tag="YMR066W"
/note="Mitochondrial hypothetical protein"
/codon_start=1
/product="Sov1p"
/protein_id="NP_013782.1"
/db_xref="GI:6323711"
/db_xref="SGD:S000004670"
/db_xref="GeneID:855088"
/translation="MFKYNRSLCSSALIAKSQIRFYRLKRAPLNYASHIPEVLNKTII
GPDEPEKCLILKGKTSEEIENNLLSNKKFQEINPLDTIQETFIQYLKFCNETNFKRSN
KNLNRLKKTLESKDSNSTVKINAVFNYLLEECDLEIKRLNTTGQTQVYNEEKGNEDDL
EQSIMNDIFRSAQEQFEDQEGHIPLRSTSFLLEILKSFNERFNGIIKPKESITEMVTF
SQLAQAFEVVKLIPVQEMKEKGIYLVGNLLYGTGKVRLDPINESFYIESLLVFGNYKA
AYSLFITNKDKVNERWWNELGLMITLRSNHLRNFRKLLAETDAKYSTKYSYLSPRVTK
LSIRKYLSIGNVTEANILTDRFIKLVEEVGIIRMKDEQEELPTGVKNFQNEKHATEFL
NELEIPSDHDYISIVDFHLYKRNIPMAAQLISKYMEIPGTTQEDAAFLLVKTKLNMLK
DFEKLRNIFAQNKDYVVPENNVKMLQEAFESVITKYNTNSPIYNELLFENVSALTKSI
VLTDFLEEFITKQASGQWMELNSVSRSRKFNGLLNILLGTGEEEKAYNILKKLEEASK
KSKTDPDLLYNQFYSEVNAYHYAKFVEFYSLQIQNMKAQNTPSFRKKEFKQKVKSLLK
RMQESEVIPNAVFLREILNFYDSMYDFNSSFEIINPLLESKQQVSSESSLSTSNPCRF
YNRRIITKPLYHKIWSVYCHYYHVLQNNSRILSKKSSIVKKLIKRQIKIHPTCHPRVL
FQMTAENGEILPDKTFSKLIVSTFMKSGDLEAIPAILTFLTKKFDLNIDYDLSMYILK
GLKRQYLRDISNISKDACEYKLRKAELMNNESILKNIPQGTNQENTISHLIREILIFI
KWKEKSDCSTFLMVEDAFKELGTEFTLLEELIEDVNKLKIKA"
gene complement(404323..405573)
/gene="UBX4"
/locus_tag="YMR067C"
/gene_synonym="CUI1"
/db_xref="GeneID:855089"
mRNA complement(404323..405573)
/gene="UBX4"
/locus_tag="YMR067C"
/gene_synonym="CUI1"
/product="Ubx4p"
/transcript_id="NM_001182565.1"
/db_xref="GI:296147185"
/db_xref="GeneID:855089"
CDS complement(404323..405573)
/gene="UBX4"
/locus_tag="YMR067C"
/gene_synonym="CUI1"
/note="UBX domain-containing protein that interacts with
Cdc48p; involved in degradation of polyubiquitinated
proteins via the ERAD (ER-associated degradation) pathway;
modulates the Cdc48p-Nplp-Ufd1p AAA ATPase complex during
its role in delivery of misfolded proteins to the
proteasome; protein abundance increases in response to DNA
replication stress"
/codon_start=1
/product="Ubx4p"
/protein_id="NP_013783.1"
/db_xref="GI:6323712"
/db_xref="SGD:S000004671"
/db_xref="GeneID:855089"
/translation="MPMVTVKYNFQLFKCKVSLNSTLNDVLHQSIQFFQLHTSSNDWS
LIHLDKPVPLDLPWRLLNLPTGVNLELSKSSNFPVANKTNREDIPFNTIKIRFQIPGR
DSVVKEMPSDQPIAPILRQMSGAAGDDFKIQVFSKIIEFKTIKDENLTLENLGIQEPS
SVRLIFNNTSHSEGISANSAIHPKQTPPTMTNPETVASLPPHELHKPSVFLPSDEPLA
VIKDQIEDEEDYELTVEQAKKYQKMLSSKAGTLGGPILTKRLREQSANNLPKKNKAIS
ECLLRVKFPDRSHIQIAFKPNEDMRTVYNVVSQFLIDENMPFTLNQSHPFKPLAKDDK
KLLDDLEFGSKTMLLFETNSNSNGPLIKAHLLEDAQKITHETRTTPSVNTINKSNPQG
PSDNATSIKKTLNRVPKWMKLSKK"
gene 406304..407584
/gene="AVO2"
/locus_tag="YMR068W"
/db_xref="GeneID:855090"
mRNA 406304..407584
/gene="AVO2"
/locus_tag="YMR068W"
/product="Avo2p"
/transcript_id="NM_001182566.1"
/db_xref="GI:296147186"
/db_xref="GeneID:855090"
CDS 406304..407584
/gene="AVO2"
/locus_tag="YMR068W"
/note="Component of a complex containing the Tor2p kinase
and other proteins, which may have a role in regulation of
cell growth"
/codon_start=1
/product="Avo2p"
/protein_id="NP_013784.1"
/db_xref="GI:6323713"
/db_xref="SGD:S000004672"
/db_xref="GeneID:855090"
/translation="MLKEPSVRLREAIIEGNLLIVKRLLRRNPDLLTNIDSENGWSSL
HYASYHGRYLICVYLIQLGHDKHELIKTFKGNTCVHLALMKGHEQTLHLLLQQFPRFI
NHRGENGRAPIHIACMNDYYQCLSLLIGVGADLWVMDTNGDTPLHVCLEYGSISCMKM
LLNEGEVSLDDNVRDKGNWKPIDVAQTFEVGNIYSKVLKEVKKKGPPLGAGKKPSSFR
TPILNAKATFEDGPSPVLSMNSPYSLYSNNSPLPVLPRRISTHTTSGNGGNRRSSITN
PVFNPRKPTLSTDSFSSSSNSSSRLRVNSINVKTPVGVSPKKELVSESVRHSATPTSP
HNNIALINRYLLPNKSNDNVRGDSQTATINDDGGGGNGGDATIGMGLRKDPDDENENK
YKIKVNNGEPRRRVSLLNIPISKLRNSNNTRAED"
gene 407709..408566
/gene="NAT4"
/locus_tag="YMR069W"
/gene_synonym="NAA40"
/db_xref="GeneID:855091"
mRNA 407709..408566
/gene="NAT4"
/locus_tag="YMR069W"
/gene_synonym="NAA40"
/product="Nat4p"
/transcript_id="NM_001182567.1"
/db_xref="GI:296147187"
/db_xref="GeneID:855091"
CDS 407709..408566
/gene="NAT4"
/locus_tag="YMR069W"
/gene_synonym="NAA40"
/EC_number="2.3.1.-"
/note="N alpha-acetyl-transferase, involved in acetylation
of the N-terminal residues of histones H4 and H2A"
/codon_start=1
/product="Nat4p"
/protein_id="NP_013785.1"
/db_xref="GI:6323714"
/db_xref="SGD:S000004673"
/db_xref="GeneID:855091"
/translation="MRSSVYSENTYNCIRTSKEHLTERRRVAMAPMFQHFLNLCVEKF
PESIEHKDTDGNGNFTTAILEREIIYIPEDDTDSIDSVDSLKCINYKLHKSRGDQVLD
ACVQLIDKHLGAKYRRASRIMYGNRKPWKANKLAEMKSAGLVYVCYWDNGVLGAFTSF
MLTEETGLVEGDALHEVSVPVIYLYEVHVASAHRGHGIGRRLLEHALCDGVARHTRRM
CDNFFGVALTVFSDNTRARRLYEALGFYRAPGSPAPASPTIRHTRHGGGRVVVPCDPL
YYVYCLHMP"
gene 409154..410626
/gene="MOT3"
/locus_tag="YMR070W"
/gene_synonym="ROX7"
/db_xref="GeneID:855092"
mRNA 409154..410626
/gene="MOT3"
/locus_tag="YMR070W"
/gene_synonym="ROX7"
/product="Mot3p"
/transcript_id="NM_001182568.1"
/db_xref="GI:296147188"
/db_xref="GeneID:855092"
CDS 409154..410626
/gene="MOT3"
/locus_tag="YMR070W"
/gene_synonym="ROX7"
/note="Transcriptional repressor and activator with two
C2-H2 zinc fingers; involved in repression of a subset of
hypoxic genes by Rox1p, repression of several DAN/TIR
genes during aerobic growth, and repression of ergosterol
biosynthetic genes in response to hyperosmotic stress;
contributes to recruitment of the Tup1p-Cyc8p general
repressor to promoters; involved in positive
transcriptional regulation of CWP2 and other genes; can
form the [MOT3+] prion"
/codon_start=1
/product="Mot3p"
/protein_id="NP_013786.1"
/db_xref="GI:6323715"
/db_xref="SGD:S000004674"
/db_xref="GeneID:855092"
/translation="MNADHHLQQQQQQRQQHQQQQHQQQQHQHQHQQQQHTILQNVSN
TNNIGSDSLASQPFNTTTVSSNKDDVMVNSGARELPMPLHQQQYIYPYYQYTSNNSNN
NNVTAGNNMSASPIVHNNSNNSNNSNISASDYTVANNSTSNNNNNNNNNNNNNNNIHP
NQFTAAANMNSNAAAAAYYSFPTANMPIPQQDQQYMFNPASYISHYYSAVNSNNNGNN
AANNGSNNSSHSAPAPAPGPPHHHHHHSNTHNNLNNGGAVNTNNAPQHHPTIITDQFQ
FQLQQNPSPNLNLNINPAQPLHLPPGWKINTMPQPRPTTAPNHPPAPVPSSNPVASNL
VPAPSSDHKYIHQCQFCEKSFKRKSWLKRHLLSHSQQRHFLCPWCLSRQKRKDNLLQH
MKLKHTNYLLDELKKNNIIFNYNNSSSSNNNNDNNNNNNSNSASGSGGAGAAAAAATA
PENEDGNGYDTNIKTLINDGVLNKDDVKRVLNNLIVSHNK"
gene complement(410762..411265)
/gene="TVP18"
/locus_tag="YMR071C"
/db_xref="GeneID:855093"
mRNA complement(410762..411265)
/gene="TVP18"
/locus_tag="YMR071C"
/product="Tvp18p"
/transcript_id="NM_001182569.1"
/db_xref="GI:296147189"
/db_xref="GeneID:855093"
CDS complement(410762..411265)
/gene="TVP18"
/locus_tag="YMR071C"
/note="Integral membrane protein localized to late Golgi
vesicles along with the v-SNARE Tlg2p; may interact with
ribosomes, based on co-purification experiments"
/codon_start=1
/product="Tvp18p"
/protein_id="NP_013787.1"
/db_xref="GI:6323716"
/db_xref="SGD:S000004675"
/db_xref="GeneID:855093"
/translation="MALSLGQFINVGGMVKDLKSFNFSVYGRWFGYINIILCIALGIA
NLFHVSGVIAFGIISIIQGLVILFIEIPFLLKICPLSDNFIEFIKRFETNGWRCLFYL
AMAIIQYISIAVMATSLIVVAVGLTISSISYAVAYTKHQEFQNTNIIKNPTDDDFPHE
AVVREML"
gene 411569..412120
/gene="ABF2"
/locus_tag="YMR072W"
/db_xref="GeneID:855094"
mRNA 411569..412120
/gene="ABF2"
/locus_tag="YMR072W"
/product="Abf2p"
/transcript_id="NM_001182570.1"
/db_xref="GI:296147190"
/db_xref="GeneID:855094"
CDS 411569..412120
/gene="ABF2"
/locus_tag="YMR072W"
/note="Mitochondrial DNA-binding protein involved in
mitochondrial DNA replication and recombination, member of
HMG1 DNA-binding protein family; activity may be regulated
by protein kinase A phosphorylation"
/codon_start=1
/product="Abf2p"
/protein_id="NP_013788.1"
/db_xref="GI:6323717"
/db_xref="SGD:S000004676"
/db_xref="GeneID:855094"
/translation="MNSYSLLTRSFHESSKPLFNLASTLLKASKRTQLRNELIKQGPK
RPTSAYFLYLQDHRSQFVKENPTLRPAEISKIAGEKWQNLEADIKEKYISERKKLYSE
YQKAKKEFDEKLPPKKPAGPFIKYANEVRSQVFAQHPDKSQLDLMKIIGDKWQSLDQS
IKDKYIQEYKKAIQEYNARYPLN"
gene complement(412268..412873)
/gene="IRC21"
/locus_tag="YMR073C"
/db_xref="GeneID:855095"
mRNA complement(412268..412873)
/gene="IRC21"
/locus_tag="YMR073C"
/product="Irc21p"
/transcript_id="NM_001182571.1"
/db_xref="GI:296147191"
/db_xref="GeneID:855095"
CDS complement(412268..412873)
/gene="IRC21"
/locus_tag="YMR073C"
/note="hypothetical protein; may be involved in resistance
to carboplatin and cisplatin; null mutant displays
increase in spontaneous Rad52p foci; contains a
lipid-binding domain and binds cardiolipin in a
large-scale study"
/codon_start=1
/product="Irc21p"
/protein_id="NP_013789.1"
/db_xref="GI:6323718"
/db_xref="SGD:S000004677"
/db_xref="GeneID:855095"
/translation="MSSDGMNRDVSNSKPNVRFAAPQRLSVAHPAISSPLHMPMSKSS
RKPLVRTKIRLDPGHSALDWHSLTSNPANYYTKFVSLQLIQDLLDDPVFQKDNFKFSP
SQLKNQLLVQKIPLYKIMPPLRINRKIVKKHCKGEDELWCVINGKVYDISSYLKFHPG
GTDILIKHRNSDDLITYFNKYHQWVNYEKLLQVCFIGVVCE"
gene complement(413036..413473)
/locus_tag="YMR074C"
/db_xref="GeneID:855096"
mRNA complement(413036..413473)
/locus_tag="YMR074C"
/product="hypothetical protein"
/transcript_id="NM_001182572.1"
/db_xref="GI:296147192"
/db_xref="GeneID:855096"
CDS complement(413036..413473)
/locus_tag="YMR074C"
/note="Protein with homology to human PDCD5; PDCD5 is
involved in programmed cell death; N-terminal region forms
a conserved triple-helix bundle structure; overexpression
promotes H2O2-induced apoptosis; YMR074C is not an
essential gene; protein abundance increases in response to
DNA replication stress"
/codon_start=1
/product="hypothetical protein"
/protein_id="NP_013790.1"
/db_xref="GI:6323719"
/db_xref="SGD:S000004678"
/db_xref="GeneID:855096"
/translation="MDPELQAIREARLAQLKNNSGGTNGDRNSGANNGGGENSAPVGA
AIANFLEPQALERLSRVALVRRDRAQAVETYLKKLIATNNVTHKITEAEIVSILNGIA
KQQNSQNNSKIIFERKDFSEDLNSFDKQNAKNDDDEDDDDFFD"
gene 413982..416036
/gene="RCO1"
/locus_tag="YMR075W"
/db_xref="GeneID:855097"
mRNA 413982..416036
/gene="RCO1"
/locus_tag="YMR075W"
/product="Rco1p"
/transcript_id="NM_001182574.1"
/db_xref="GI:296147193"
/db_xref="GeneID:855097"
CDS 413982..416036
/gene="RCO1"
/locus_tag="YMR075W"
/note="Essential subunit of the histone deacetylase Rpd3S
complex; interacts with Eaf3p"
/codon_start=1
/product="Rco1p"
/protein_id="NP_013791.1"
/db_xref="GI:6323720"
/db_xref="SGD:S000004680"
/db_xref="GeneID:855097"
/translation="MDTSKKDTTRSPSHSNSSSPSSSSLSSSSSKEKKRPKRLSSQNV
NYDLKRRKIITSEGIERSFKNEHSNLAVEDNIPEEEPKELLEKDSKGNIIKLNEPSTI
SEDSKVSVTGLPLNKGPSEKIKRESLWNYRKNLGGQSNNSEMTLVPSKRFTQVPKNFQ
DLNRNDLKTFLTENMTEESNIRSTIGWNGDIINRTRDREPESDRDNKKLSNIRTKIIL
STNATYDSKSKLFGQNSIKSTSNASEKIFRDKNNSTIDFENEDFCSACNQSGSFLCCD
TCPKSFHFLCLDPPIDPNNLPKGDWHCNECKFKIFINNSMATLKKIESNFIKQNNNVK
IFAKLLFNIDSHNPKQFQLPNYIKETFPAVKTGSRGQYSDENDKIPLTDRQLFNTSYG
QSITKLDSYNPDTHIDSNSGKFLICYKCNQTRLGSWSHPENSRLIMTCDYCQTPWHLD
CVPRASFKNLGSKWKCPLHSPTKVYKKIHHCQEDNSVNYKVWKKQRLINKKNQLYYEP
LQKIGYQNNGNIQIIPTTSHTDYDFNQDFKITQIDENSIKYDFFDKIYKSKMVQKRKL
FQFQESLIDKLVSNGSQNGNSEDNMVKDIASLIYFQVSNNDKSSNNKSASKSNNLRKL
WDLKELTNVVVPNELDSIQFNDFSSDEIKHLLYLKKIIESKPKEELLKFLNIENPENQ
SE"
gene complement(416196..420029)
/gene="PDS5"
/locus_tag="YMR076C"
/db_xref="GeneID:855099"
mRNA complement(416196..420029)
/gene="PDS5"
/locus_tag="YMR076C"
/product="Pds5p"
/transcript_id="NM_001182575.1"
/db_xref="GI:296147194"
/db_xref="GeneID:855099"
CDS complement(416196..420029)
/gene="PDS5"
/locus_tag="YMR076C"
/note="Protein required for establishment and maintenance
of sister chromatid condensation and cohesion, colocalizes
with cohesin on chromosomes, may function as a
protein-protein interaction scaffold; also required during
meiosis"
/codon_start=1
/product="Pds5p"
/protein_id="NP_013793.1"
/db_xref="GI:6323722"
/db_xref="SGD:S000004681"
/db_xref="GeneID:855099"
/translation="MAKGAVTKLKFNSPIISTSDQLISTNELLDRLKALHEELASLDQ
DNTDLTGLDKYRDALVSRKLLKHKDVGIRAFTACCLSDILRLYAPDAPYTDAQLTDIF
KLVLSQFEQLGDQENGYHIQQTYLITKLLEYRSIVLLADLPSSNNLLIELFHIFYDPN
KSFPARLFNVIGGILGEVISEFDSVPLEVLRLIFNKFLTYNPNEIPEGLNVTSDCGYE
VSLILCDTYSNRMSRHLTKYYSEIIHEATNDDNNSRLLTVVVKLHKLVLRLWETVPEL
INAVIGFIYHELSSENELFRKEATKLIGQILTSYSDLNFVSTHSDTFKAWISKIADIS
PDVRVEWTESIPQIIATREDISKELNQALAKTFIDSDPRVRRTSVMIFNKVPVTEIWK
NITNKAIYTSLLHLAREKHKEVRELCINTMAKFYSNSLNEIERTYQNKEIWEIIDTIP
STLYNLYYINDLNINEQVDSVIFEYLLPFEPDNDKRVHRLLTVLSHFDKKAFTSFFAF
NARQIKISFAISKYIDFSKFLNNQESMSSSQGPIVMNKYNQTLQWLASGLSDSTKAID
ALETIKQFNDERIFYLLNACVTNDIPFLTFKNCYNELVSKLQTPGLFKKYNISTGASI
MPRDIAKVIQILLFRASPIIYNVSNISVLLNLSNNSDAKQLDLKRRILDDISKVNPTL
FKDQIRTLKTIIKDLDDPDAEKNDNLSLEEALKTLYKASKTLKDQVDFDDTFFFTKLY
DFAVESKPEITKYATKLIALSPKAEETLKKIKIRILPLDLQKDKYFTSHIIVLMEIFK
KFPHVLNDDSTDIISYLIKEVLLSNQVVGDSKKEIDWVEDSLLSDTKYSAIGNKVFTL
KLFTNKLRSIAPDVPRDELAESFTEKTMKLFFYLIASGGELISEFNKEFYPTPSNYQT
KLRCVAGIQVLKLARISNLNNFIKPSDIIKLINLVEDESLPVRKTFLEQLKDYVANEL
ISIKFLPLVFFTAYEPDVELKTTTKIWINFTFGLKSFKKGTIFERALPRLIHAIAHHP
DIVGGLDSEGDAYLNALTTAIDYLLFYFDSIAAQENFSLLYYLSERVKNYQDKLVEDE
IDEEEGPQKEEAPKKHRPYGQKMYIIGELSQMILLNLKEKKNWQHSAYPGKLNLPSDL
FKPFATVQEAQLSFKTYIPESLTEKIQNNIKAKIGRILHTSQTQRQRLQKRLLAHENN
ESQKKKKKVHHARSQADDEEGDGDRESDSDDDSYSPSNKNETKKGHENIVMKKLRVRK
EVDYKDDEDDDIEMT"
gene complement(420588..420661)
/locus_tag="tV(AAC)M2"
/db_xref="GeneID:855100"
tRNA complement(420588..420661)
/locus_tag="tV(AAC)M2"
/product="tRNA-Val"
/note="Valine tRNA (tRNA-Val), predicted by tRNAscan-SE
analysis"
/db_xref="SGD:S000006764"
/db_xref="GeneID:855100"
gene complement(421484..422149)
/gene="VPS20"
/locus_tag="YMR077C"
/gene_synonym="CHM6; VPL10; VPT20"
/db_xref="GeneID:855101"
mRNA complement(421484..422149)
/gene="VPS20"
/locus_tag="YMR077C"
/gene_synonym="CHM6; VPL10; VPT20"
/product="Vps20p"
/transcript_id="NM_001182576.1"
/db_xref="GI:296147195"
/db_xref="GeneID:855101"
CDS complement(421484..422149)
/gene="VPS20"
/locus_tag="YMR077C"
/gene_synonym="CHM6; VPL10; VPT20"
/note="Myristoylated subunit of ESCRTIII, the endosomal
sorting complex required for transport of transmembrane
proteins into the multivesicular body pathway to the
lysosomal/vacuolar lumen; cytoplasmic protein recruited to
endosomal membranes"
/codon_start=1
/product="Vps20p"
/protein_id="NP_013794.1"
/db_xref="GI:6323723"
/db_xref="SGD:S000004682"
/db_xref="GeneID:855101"
/translation="MGQKSSKVHITKTDRAILEVKRSKDEIHKFTRRTDNLILVEKSQ
LKDLIRKNPENYKSNMKVRFLLKRIHYQEHLLQQASDQLINLENMVSTLEFKMVEKQF
INGLKNGNEILKKLNKEFSNVDELMDDVQDQIAYQNEINETLSRSLVGTSNYEDDLDK
ELDALESELNPEKMNNAKVANMPSTEGLPSLPQGEQTEQKEREEFATEERSDTKEPLA
LLS"
gene complement(422503..424728)
/gene="CTF18"
/locus_tag="YMR078C"
/gene_synonym="CHL12"
/db_xref="GeneID:855102"
mRNA complement(422503..424728)
/gene="CTF18"
/locus_tag="YMR078C"
/gene_synonym="CHL12"
/product="Ctf18p"
/transcript_id="NM_001182577.1"
/db_xref="GI:296147196"
/db_xref="GeneID:855102"
CDS complement(422503..424728)
/gene="CTF18"
/locus_tag="YMR078C"
/gene_synonym="CHL12"
/note="Subunit of a complex with Ctf8p that shares some
subunits with Replication Factor C and is required for
sister chromatid cohesion; may have overlapping functions
with Rad24p in the DNA damage replication checkpoint"
/codon_start=1
/product="Ctf18p"
/protein_id="NP_013795.1"
/db_xref="GI:6323724"
/db_xref="SGD:S000004683"
/db_xref="GeneID:855102"
/translation="MVDTAPYIGSLGRSSLFDTGDIEQAPGNNAIGINEEDIHAFVSS
TGETVQLKKKPAKLATGNISLYTNPDTVWRSDDTYGININYLLDKIEASGDDRTNAQK
TSPITGKIGSDTLWVEKWRPKKFLDLVGNEKTNRRMLGWLRQWTPAVFKEQLPKLPTE
KEVSDMELDPLKRPPKKILLLHGPPGIGKTSVAHVIAKQSGFSVSEINASDERAGPMV
KEKIYNLLFNHTFDTNPVCLVADEIDGSIESGFIRILVDIMQSDIKATNKLLYGQPDK
KDKKRKKKRSKLLTRPIICICNNLYAPSLEKLKPFCEIIAVKRPSDTTLLERLNLICH
KENMNIPIKAINDLIDLAQGDVRNCINNLQFLASNVDSRDSSASDKPACAKNTWASSN
KDSPISWFKIVNQLFRKDPHRDIKEQFYELLNQVELNGNSDRILQGCFNIFPYVKYSD
NGIRKPANISDWLFFHDLMYQSMYAHNGELLRYSALVPLVFFQTFGDIANKDDIRMKN
SEYEQRELKRANSDIVSLIMRHISVQSPLMASFTDRKSLIFEILPYLDSMISSDFNKI
RNLKLKQAIMEELVQLLKSFQLNLIQNRSEGFDVRGGLTIDPPIDEVVLLNPKHINEV
QHKRANNLSSLLAKIEENRAKKRHIDQVTEDRLQSQEMHSKKVKTGLNSSSSTIDFFK
NQYGLLKQTQELEETQKTIGSDETNQADDCNQTVKIWVKYNEGFSNAVRKNVTWNNLW
E"
gene 424989..426059
/gene="SEC14"
/locus_tag="YMR079W"
/gene_synonym="PIT1"
/db_xref="GeneID:855103"
mRNA join(424989..424997,425154..426059)
/gene="SEC14"
/locus_tag="YMR079W"
/gene_synonym="PIT1"
/product="Sec14p"
/transcript_id="NM_001182578.1"
/db_xref="GI:296147197"
/db_xref="GeneID:855103"
CDS join(424989..424997,425154..426059)
/gene="SEC14"
/locus_tag="YMR079W"
/gene_synonym="PIT1"
/note="Phosphatidylinositol/phosphatidylcholine transfer
protein; involved in regulating PtdIns, PtdCho, and
ceramide metabolism, products of which regulate
intracellular transport and UPR; functionally homologous
to mammalian PITPs"
/codon_start=1
/product="Sec14p"
/protein_id="NP_013796.1"
/db_xref="GI:6323725"
/db_xref="SGD:S000004684"
/db_xref="GeneID:855103"
/translation="MVTQQEKEFLESYPQNCPPDALPGTPGNLDSAQEKALAELRKLL
EDAGFIERLDDSTLLRFLRARKFDVQLAKEMFENCEKWRKDYGTDTILQDFHYDEKPL
IAKFYPQYYHKTDKDGRPVYFEELGAVNLHEMNKVTSEERMLKNLVWEYESVVQYRLP
ACSRAAGHLVETSCTIMDLKGISISSAYSVMSYVREASYISQNYYPERMGKFYIINAP
FGFSTAFRLFKPFLDPVTVSKIFILGSSYQKELLKQIPAENLPVKFGGKSEVDESKGG
LYLSDIGPWRDPKYIGPEGEAPEAFSMK"
gene complement(426712..429627)
/gene="NAM7"
/locus_tag="YMR080C"
/gene_synonym="IFS2; MOF4; SUP113; UPF1"
/db_xref="GeneID:855104"
mRNA complement(426712..429627)
/gene="NAM7"
/locus_tag="YMR080C"
/gene_synonym="IFS2; MOF4; SUP113; UPF1"
/product="ATP-dependent RNA helicase NAM7"
/transcript_id="NM_001182579.1"
/db_xref="GI:296147198"
/db_xref="GeneID:855104"
CDS complement(426712..429627)
/gene="NAM7"
/locus_tag="YMR080C"
/gene_synonym="IFS2; MOF4; SUP113; UPF1"
/EC_number="3.6.1.-"
/note="ATP-dependent RNA helicase of the SFI superfamily;
involved in nonsense mediated mRNA decay; required for
efficient translation termination at nonsense codons and
targeting of NMD substrates to P-bodies; involved in
telomere maintenance; forms cytoplasmic foci upon DNA
replication stress"
/codon_start=1
/product="ATP-dependent RNA helicase NAM7"
/protein_id="NP_013797.1"
/db_xref="GI:6323726"
/db_xref="SGD:S000004685"
/db_xref="GeneID:855104"
/translation="MVGSGSHTPYDISNSPSDVNVQPATQLNSTLVEDDDVDNQLFEE
AQVTETGFRSPSASDNSCAYCGIDSAKCVIKCNSCKKWFCNTKNGTSSSHIVNHLVLS
HHNVVSLHPDSDLGDTVLECYNCGRKNVFLLGFVSAKSEAVVVLLCRIPCAQTKNANW
DTDQWQPLIEDRQLLSWVAEQPTEEEKLKARLITPSQISKLEAKWRSNKDATINDIDA
PEEQEAIPPLLLRYQDAYEYQRSYGPLIKLEADYDKQLKESQALEHISVSWSLALNNR
HLASFTLSTFESNELKVAIGDEMILWYSGMQHPDWEGRGYIVRLPNSFQDTFTLELKP
SKTPPPTHLTTGFTAEFIWKGTSYDRMQDALKKFAIDKKSISGYLYYKILGHQVVDIS
FDVPLPKEFSIPNFAQLNSSQSNAVSHVLQRPLSLIQGPPGTGKTVTSATIVYHLSKI
HKDRILVCAPSNVAVDHLAAKLRDLGLKVVRLTAKSREDVESSVSNLALHNLVGRGAK
GELKNLLKLKDEVGELSASDTKRFVKLVRKTEAEILNKADVVCCTCVGAGDKRLDTKF
RTVLIDESTQASEPECLIPIVKGAKQVILVGDHQQLGPVILERKAADAGLKQSLFERL
ISLGHVPIRLEVQYRMNPYLSEFPSNMFYEGSLQNGVTIEQRTVPNSKFPWPIRGIPM
MFWANYGREEISANGTSFLNRIEAMNCERIITKLFRDGVKPEQIGVITPYEGQRAYIL
QYMQMNGSLDKDLYIKVEVASVDAFQGREKDYIILSCVRANEQQAIGFLRDPRRLNVG
LTRAKYGLVILGNPRSLARNTLWNHLLIHFREKGCLVEGTLDNLQLCTVQLVRPQPRK
TERPMNAQFNVESEMGDFPKFQDFDAQSMVSFSGQIGDFGNAFVDNTELSSYINNEYW
NFENFKSAFSQKQNRNEIDDRNLYQEEASHLNSNFARELQREEQKHELSKDFSNLGI"
gene complement(430079..431095)
/gene="ISF1"
/locus_tag="YMR081C"
/gene_synonym="MBR3"
/db_xref="GeneID:855105"
mRNA complement(430079..431095)
/gene="ISF1"
/locus_tag="YMR081C"
/gene_synonym="MBR3"
/product="Isf1p"
/transcript_id="NM_001182580.1"
/db_xref="GI:296147199"
/db_xref="GeneID:855105"
CDS complement(430079..431095)
/gene="ISF1"
/locus_tag="YMR081C"
/gene_synonym="MBR3"
/note="Serine-rich, hydrophilic protein with similarity to
Mbr1p; overexpression suppresses growth defects of hap2,
hap3, and hap4 mutants; expression is under glucose
control; cotranscribed with NAM7 in a cyp1 mutant"
/codon_start=1
/product="Isf1p"
/protein_id="NP_013798.1"
/db_xref="GI:6323727"
/db_xref="SGD:S000004686"
/db_xref="GeneID:855105"
/translation="MIASEIFERGVQDPFCQDCDYEDETDVQSFLGSNDLNDFVNSKL
ASFSFQNSSKSNNSHHSSSTNAGNTSRHIGNHTIGHHLRKIKTAPHHLYGFVPANSTN
NSNEPIRPSPRRIRANSSTLIHQLSRQSTRQSSLGDAADSCFDHKCIKPRSRHSSCYG
IPTHLYGLEKYVSSELDSLAVANDQSNDLTSPLTSVSTPASNSNSYLNLNSSSAAYPS
SYLSNEKNNRLKLISHGKISSNNVPGHSGNLNHYHRERTPSNLRRESFSLLSNGSSSS
PLQTRNNSYSNSLVKSPSNSSLNTSVASSNEESSPHTSNCLEERNPRRKSFIKLSLAS
SFSN"
gene 434788..435915
/gene="ADH3"
/locus_tag="YMR083W"
/db_xref="GeneID:855107"
mRNA 434788..435915
/gene="ADH3"
/locus_tag="YMR083W"
/product="alcohol dehydrogenase ADH3"
/transcript_id="NM_001182582.1"
/db_xref="GI:296147200"
/db_xref="GeneID:855107"
CDS 434788..435915
/gene="ADH3"
/locus_tag="YMR083W"
/EC_number="1.1.1.190"
/EC_number="1.1.1.1"
/note="Mitochondrial alcohol dehydrogenase isozyme III;
involved in the shuttling of mitochondrial NADH to the
cytosol under anaerobic conditions and ethanol production"
/codon_start=1
/product="alcohol dehydrogenase ADH3"
/protein_id="NP_013800.1"
/db_xref="GI:6323729"
/db_xref="SGD:S000004688"
/db_xref="GeneID:855107"
/translation="MLRTSTLFTRRVQPSLFSRNILRLQSTAAIPKTQKGVIFYENKG
KLHYKDIPVPEPKPNEILINVKYSGVCHTDLHAWHGDWPLPVKLPLVGGHEGAGVVVK
LGSNVKGWKVGDLAGIKWLNGSCMTCEFCESGHESNCPDADLSGYTHDGSFQQFATAD
AIQAAKIQQGTDLAEVAPILCAGVTVYKALKEADLKAGDWVAISGAAGGLGSLAVQYA
TAMGYRVLGIDAGEEKEKLFKKLGGEVFIDFTKTKNMVSDIQEATKGGPHGVINVSVS
EAAISLSTEYVRPCGTVVLVGLPANAYVKSEVFSHVVKSINIKGSYVGNRADTREALD
FFSRGLIKSPIKIVGLSELPKVYDLMEKGKILGRYVVDTSK"
gene 436628..437416
/locus_tag="YMR084W"
/db_xref="GeneID:855108"
mRNA 436628..437416
/locus_tag="YMR084W"
/product="hypothetical protein"
/transcript_id="NM_001182583.1"
/db_xref="GI:296147201"
/db_xref="GeneID:855108"
CDS 436628..437416
/locus_tag="YMR084W"
/note="hypothetical protein; YMR084W and adjacent ORF
YMR085W are merged in related strains, and together are
paralogous to glutamine-fructose-6-phosphate
amidotransferase GFA1"
/codon_start=1
/product="hypothetical protein"
/protein_id="NP_013801.1"
/db_xref="GI:6323730"
/db_xref="SGD:S000004689"
/db_xref="GeneID:855108"
/translation="MCGIFGYCNFLIEKTRGEIIDTLIEGLQALEYKEYDSSGISIQG
DELESLNIYKQTGKISSLKEEIDLYNLNKNLPFISHCGIAHTRRATHGGLRRANCHPH
NSDPSNEFVVVHNGVITNFANLKALLMAKGYVFKSDTDTECIPKLYKHIYDTSIELGY
NLDFHVLTNLVLKELEGSYGLLCTSSHFPDEVVAARKGSPLVIGVKGKTDMDVNFVEV
EYLDQEEDYLKLNTQTKSSGNVLAAAPVKYNTCLRKSPPFVHNT"
gene 437491..438789
/locus_tag="YMR085W"
/db_xref="GeneID:855109"
mRNA 437491..438789
/locus_tag="YMR085W"
/product="hypothetical protein"
/transcript_id="NM_001182584.1"
/db_xref="GI:296147202"
/db_xref="GeneID:855109"
CDS 437491..438789
/locus_tag="YMR085W"
/note="hypothetical protein; YMR085W and adjacent ORF
YMR084W are merged in related strains, and together are
paralogous to glutamine-fructose-6-phosphate
amidotransferase GFA1"
/codon_start=1
/product="hypothetical protein"
/protein_id="NP_013802.1"
/db_xref="GI:6323731"
/db_xref="SGD:S000004690"
/db_xref="GeneID:855109"
/translation="MEFYLSSDCASLARYVSKVVYLEDNDIAHIYDGELHIHCSKIGS
EDFSFRTVQKLELELSKIKKGPYDNFMQKEIYEQCETTKNVMRGRVDAFTNRVVLGGL
ENWLTELRRAKRIIMIASKASFHSCLAARPIFEELMEVPVNVELALDFVDRNCCIFRN
DVCIFVSRSGETTDTINALNYCIKKEAVTIGVVNCSGSSISRFTHCGVHTNTGPEKGI
ATTKSYTSQYIALVMIALWMSEDLVSKIERRKEIIQALTIVPSQIKEVLELEPLIIEL
CDKKLKQHDTFLLLGRGYQFASALEGASKMKEISYVHSESILTNELGHRVLAVASDNP
PIIAFATKDAFSPKIASCIDQIIERKGNPIIICNKGHKIWEQDKQKGNVVTLEVPQTV
DCLQGILNVIPLQLISYWLAIKKDIGVDLPRDSAMSAPDI"
gene 439208..442090
/gene="SEG1"
/locus_tag="YMR086W"
/db_xref="GeneID:855110"
mRNA 439208..442090
/gene="SEG1"
/locus_tag="YMR086W"
/product="Seg1p"
/transcript_id="NM_001182586.1"
/db_xref="GI:296147203"
/db_xref="GeneID:855110"
CDS 439208..442090
/gene="SEG1"
/locus_tag="YMR086W"
/note="Component of eisosome required for proper eisosome
assembly; precedes Pil1p/Lsp1p during eisosome formation
and controls eisosome length and shape; Seg1p-GFP
diffusely distributed and forms heterogeneous patches at
the plasma membrane in small buds, also found in medium
and large buds; may interact with ribosomes, based on
co-purification experiments; expression is repressed by
cAMP; similar to A. gossypii SEG gene and to S. pombe
Sle1p, important for generating eisosomes"
/codon_start=1
/product="Seg1p"
/protein_id="NP_013803.1"
/db_xref="GI:6323732"
/db_xref="SGD:S000004692"
/db_xref="GeneID:855110"
/translation="MFRRRTTAPEMEQADPTAVAAAASIGKLLMKKGNQSDNEQRPTY
RSASMTNLRKPSAPKRMSSISSISSESRRSDGKGRPGKINSLTQRSSMGKGDSLNSPL
TKEPQHKTRSHNRTSSLPNQRGQQSRNSSGLQRQKSKTHQRISYDEAQRTFKDFGGPQ
ARGILTGQHRTENPSGSIPLRTTRKYIPGPNGLVAIEVPVEKPSNANTSKLLRRSNSA
HSALNARNGSLLRKKVSQESLHSQPKKTSSLGNTSSTQAKKGQKAVQERNLAKKHPIN
SNVPLIETQVREETDQELKLDNSNSSESETVVNSENNLEKPSSLNIEKDDLSKLIHEN
IELESFIEEKGKEKPLNSDQEDVFISEKTVKGDVQWPKNNRQASTLEKTFNYDNEEKR
EGNKPVAEHPLPEAEVDDKSVEQLNNISSSGSYSAQGSVENSKPENGNKNLENDTTSS
PTQDLDEKSRSIEEKDTLEGTESSKKVEKPDNCCEKISGANTSSKKGNVGDTKDEFFD
TVEESDQKTSKSNSSKNTDHSNQTEPTPSLAQYLRTSNTYLSRKNQSKQAEQEKFHKP
EAPMVPVTKVVTPIKSALKKSSGSSNHDSSMYSDNSPANGAYLSLTTAENTRLNAQMT
MSDSVSRRASLKRSSIKRPQSVGQFRSIRSNSPSPPEKINNKRHSAIPLGTPEKGKPK
RNSVMASLSKNSQQIQEPASVYESNGPNKPKNQINKNIKRGSQIAQNNKPSTKDMNSI
LYPKEPPPRKSSFEKTRSNESHLGFKKLSLRNGNFEEALSESYNGQASQNSTNVNRTD
TAQEFFKYLGHSSRFADSDSEDESQFFNQGPSKYNTETEGNKTSGNKNSNGGNGAFSL
FKSKSKQKENNVVSPGVSSPNHTTTDPAITSKKVDKKFSGLSLRAASEAEPAKNSNPS
MTNRLRFSSNPENGESRLPQAQEVSVTKEKKGSFGKKLKKIFGRKK"
gene 442527..443381
/locus_tag="YMR087W"
/db_xref="GeneID:855112"
mRNA 442527..443381
/locus_tag="YMR087W"
/product="hypothetical protein"
/transcript_id="NM_001182587.1"
/db_xref="GI:296147204"
/db_xref="GeneID:855112"
CDS 442527..443381
/locus_tag="YMR087W"
/note="Putative ADP-ribose-1''-monophosphatase that
converts ADP-ribose-1''-monophosphate to ADP-ribose; may
have a role in tRNA splicing; contains an A1pp domain"
/codon_start=1
/product="hypothetical protein"
/protein_id="NP_013805.1"
/db_xref="GI:6323734"
/db_xref="SGD:S000004693"
/db_xref="GeneID:855112"
/translation="MTGSLNRHSLLNGVKKMRIILCDTNEVVTNLWQESIPHAYIQND
KYLCIHHGHLQSLMDSMRKGDAIHHGHSYAIVSPGNSYGYLGGGFDKALYNYFGGKPF
ETWFRNQLGGRYHTVGSATVVDLQRCLEEKTIECRDGIRYIIHVPTVVAPSAPIFNPQ
NPLKTGFEPVFNAMWNALMHSPKDIDGLIIPGLCTGYAGVPPIISCKSMAFALRLYMA
GDHISKELKNVLIMYYLQYPFEPFFPESCKIECQKLGIDIEMLKSFNVEKDAIELLIP
RRILTLDL"
gene complement(443414..445102)
/gene="VBA1"
/locus_tag="YMR088C"
/db_xref="GeneID:855113"
mRNA complement(443414..445102)
/gene="VBA1"
/locus_tag="YMR088C"
/product="Vba1p"
/transcript_id="NM_001182588.1"
/db_xref="GI:296147205"
/db_xref="GeneID:855113"
CDS complement(443414..445102)
/gene="VBA1"
/locus_tag="YMR088C"
/note="Permease of basic amino acids in the vacuolar
membrane"
/codon_start=1
/product="Vba1p"
/protein_id="NP_013806.1"
/db_xref="GI:6323735"
/db_xref="SGD:S000004694"
/db_xref="GeneID:855113"
/translation="MQTLDETSNLLPPPEEAEAPPLEQKFHEYNLALPKFPILFSLWL
GSFLSSLDSTIVANIMNRVAEEFSESSKKQWIATSFLLTNTAFQPLYGKLSDITGRKS
ALLTAQFFFGLGCLLTCFARNVTEFSIARAICGIGAGGLNAISSIAVSDICTARERGV
YQGYANIVFGFGQLLGAPLGGVFIETIGWRALFGIQVPVIMLCSVLAIKNINIKLFHV
PPMKERYTLKNLSRIDIFGSLSLVATISGVLFLCSSQLNKLYLALFTIGSFIVFILVE
RYYATEKILPFELLTRSFCLSSAVTVISSFVVFGEIFRSPIYLQLLQNISVTKTGLFL
IFPSISVAVGSLVTGWVLRNTKINLAHCAYQIIFGGMIMQLLGLGLGYFLLSHLNPDY
TIYDMLESITFRSNSIWWKLIYVFASVLVSFGYACLLVATLVSIVFTVEKSQQGTMTG
VFYLWRSIGNVLGASLTLVSYENSLSSMLWNYMFKTKRDDEYHFTKKQYYSLINDSSY
LRGPNFPTDIFVRILDVYKKAFLISYIPNIALAAVGIVLSLYLVKHTYKRSSSS"
gene complement(445609..448086)
/gene="YTA12"
/locus_tag="YMR089C"
/gene_synonym="RCA1"
/db_xref="GeneID:855114"
mRNA complement(445609..448086)
/gene="YTA12"
/locus_tag="YMR089C"
/gene_synonym="RCA1"
/product="m-AAA protease subunit YTA12"
/transcript_id="NM_001182589.1"
/db_xref="GI:296147206"
/db_xref="GeneID:855114"
CDS complement(445609..448086)
/gene="YTA12"
/locus_tag="YMR089C"
/gene_synonym="RCA1"
/EC_number="3.4.24.-"
/note="Component, with Afg3p, of the mitochondrial inner
membrane m-AAA protease that mediates degradation of
misfolded or unassembled proteins and is also required for
correct assembly of mitochondrial enzyme complexes"
/codon_start=1
/product="m-AAA protease subunit YTA12"
/protein_id="NP_013807.1"
/db_xref="GI:6323736"
/db_xref="SGD:S000004695"
/db_xref="GeneID:855114"
/translation="MLLLSWSRIATKVVRRPVRFRSYYGLTHIKSLHTQYRLLNRLQE
NKSGNKNEDNNEDAKLNKEIPTDEEVEAIRKQVEKYIEQTKNNTIPANWKEQKRKIDE
SIRRLEDAVLKQESNRIQEERKEKEEENGPSKAKSNRTKEQGYFEGNNSRNIPPPPPP
PPPKPPLNDPSNPVSKNVNLFQIGLTFFLLSFLLDLLNSLEEQSEITWQDFREKLLAK
GYVAKLIVVNKSMVKVMLNDNGKNQADNYGRNFYYFTIGSIDSFEHKLQKAQDELDID
KDFRIPVLYVQEGNWAKAMFQILPTVLMIAGIIWLTRRSAQAAGGSRGGIFGLSRSKA
KKFNTETDVKIKFKDVAGCDEAKEEIMEFVSFLKEPSRYEKMGAKIPRGAILSGPPGT
GKTLLAKATAGEAGVPFYFVSGSEFVEMFVGVGAARVRDLFKTARENAPSIVFIDEID
AIGKARQKGNFSGANDERENTLNQMLVEMDGFTPADHVVVLAGTNRPDILDKALLRPG
RFDRHINIDKPELEGRKAIFAVHLHHLKLAGEIFDLKNRLAALTPGFSGADIANVCNE
AALIAARSDEDAVKLNHFEQAIERVIGGVERKSKLLSPEEKKVVAYHEAGHAVCGWYL
KYADPLLKVSIIPRGQGALGYAQYLPGDIFLLTEQQLKDRMTMSLGGRVSEELHFPSV
TSGASDDFKKVTSMATAMVTELGMSDKIGWVNYQKRDDSDLTKPFSDETGDIIDSEVY
RIVQECHDRCTKLLKEKAEDVEKIAQVLLKKEVLTREDMIDLLGKRPFPERNDAFDKY
LNDYETEKIRKEEEKNEKRNEPKPSTN"
gene 449245..449928
/locus_tag="YMR090W"
/db_xref="GeneID:855115"
mRNA 449245..449928
/locus_tag="YMR090W"
/product="hypothetical protein"
/transcript_id="NM_001182590.1"
/db_xref="GI:296147207"
/db_xref="GeneID:855115"
CDS 449245..449928
/locus_tag="YMR090W"
/note="hypothetical protein with similarity to
DTDP-glucose 4,6-dehydratases; GFP-fusion protein
localizes to the cytoplasm; up-regulated in response to
the fungicide mancozeb; not essential for viability"
/codon_start=1
/product="hypothetical protein"
/protein_id="NP_013808.1"
/db_xref="GI:6323737"
/db_xref="SGD:S000004696"
/db_xref="GeneID:855115"
/translation="MSPMKVAVVGASGKVGRLLINQLKANDSFSTPLAIVRTQDQVNY
FKNEVGVDASLTDIENASVSEITDAIKAYDAVVFSAGAGGKGMERIFTVDLDGCIKVV
EACEKAGIKRFVVVSALKAEDRDFWYNIKGLREYYIAKRSADREVRNSNLDYTILQPG
SLELNKGTGLLQPLDKLEEKASVNYSINREDVASFIVESLLHPNATVKKTISLVNGNE
PMEKFIQSL"
gene complement(450058..451365)
/gene="NPL6"
/locus_tag="YMR091C"
/gene_synonym="RSC7"
/db_xref="GeneID:855116"
mRNA complement(450058..451365)
/gene="NPL6"
/locus_tag="YMR091C"
/gene_synonym="RSC7"
/product="Npl6p"
/transcript_id="NM_001182591.1"
/db_xref="GI:296147208"
/db_xref="GeneID:855116"
CDS complement(450058..451365)
/gene="NPL6"
/locus_tag="YMR091C"
/gene_synonym="RSC7"
/note="Component of the RSC chromatin remodeling complex;
interacts with Rsc3p, Rsc30p, Ldb7p, and Htl1p to form a
module important for a broad range of RSC functions;
involved in nuclear protein import and maintenance of
proper telomere length"
/codon_start=1
/product="Npl6p"
/protein_id="NP_013809.1"
/db_xref="GI:6323738"
/db_xref="SGD:S000004697"
/db_xref="GeneID:855116"
/translation="MSDSEGGLASEVEHEKRSRSTSNRPNYAIDTEDLDIDENDENED
DDYREEEANEGVNEEEISDEEEQINKSGRNKRRHVDEEEDLSEDKGVTRSRNRSKFKK
PVFPGIDDAEENLNPLKVVNEEYVLPDDPEGETKITADGDLLGGREFLVRTFTLTEKG
NRKFMLATEPARIVGFRDSYLFFQTHPNLYKFILNQTQKNDLIDRGVLPYSYRNRQIA
LVTARGVFKEFGAKIIRGGKHITDDYYASELRTKGNVIEGKLAGDPIDKSARALETMM
YPASENGINPAKNQVEFFEHRPHGHMSNSNIIASGSKLSSTNWLYQHSAACSRFNSDL
FYDRVKVLLVDQQGLRDAYTNILHIPESTQSTTVLGWRRSKNDSPSDTSIVYETVIHD
NDLNKPKTGLSEIPKEIYEDVVDEDVLRAITEQQNFEKCNEYI"
gene complement(451632..453479)
/gene="AIP1"
/locus_tag="YMR092C"
/db_xref="GeneID:855117"
mRNA complement(451632..453479)
/gene="AIP1"
/locus_tag="YMR092C"
/product="Aip1p"
/transcript_id="NM_001182592.1"
/db_xref="GI:296147209"
/db_xref="GeneID:855117"
CDS complement(451632..453479)
/gene="AIP1"
/locus_tag="YMR092C"
/note="Actin cortical patch component; interacts with the
actin depolymerizing factor cofilin; required to restrict
cofilin localization to cortical patches; contains WD
repeats; protein increases in abundance and relocalizes
from cytoplasm to plasma membrane upon DNA replication
stress"
/codon_start=1
/product="Aip1p"
/protein_id="NP_013810.1"
/db_xref="GI:6323739"
/db_xref="SGD:S000004698"
/db_xref="GeneID:855117"
/translation="MSSISLKEIIPPQPSTQRNFTTHLSYDPTTNAIAYPCGKSAFVR
CLDDGDSKVPPVVQFTGHGSSVVTTVKFSPIKGSQYLCSGDESGKVIVWGWTFDKESN
SVEVNVKSEFQVLAGPISDISWDFEGRRLCVVGEGRDNFGVFISWDSGNSLGEVSGHS
QRINACHLKQSRPMRSMTVGDDGSVVFYQGPPFKFSASDRTHHKQGSFVRDVEFSPDS
GEFVITVGSDRKISCFDGKSGEFLKYIEDDQEPVQGGIFALSWLDSQKFATVGADATI
RVWDVTTSKCVQKWTLDKQQLGNQQVGVVATGNGRIISLSLDGTLNFYELGHDEVLKT
ISGHNKGITALTVNPLISGSYDGRIMEWSSSSMHQDHSNLIVSLDNSKAQEYSSISWD
DTLKVNGITKHEFGSQPKVASANNDGFTAVLTNDDDLLILQSFTGDIIKSVRLNSPGS
AVSLSQNYVAVGLEEGNTIQVFKLSDLEVSFDLKTPLRAKPSYISISPSETYIAAGDV
MGKILLYDLQSREVKTSRWAFHTSKINAISWKPAEKGANEEEIEEDLVATGSLDTNIF
IYSVKRPMKIIKALNAHKDGVNNLLWETPSTLVSSGADACIKRWNVVLE"
gene 454015..455556
/gene="UTP15"
/locus_tag="YMR093W"
/db_xref="GeneID:855118"
mRNA 454015..455556
/gene="UTP15"
/locus_tag="YMR093W"
/product="Utp15p"
/transcript_id="NM_001182593.1"
/db_xref="GI:296147210"
/db_xref="GeneID:855118"
CDS 454015..455556
/gene="UTP15"
/locus_tag="YMR093W"
/note="Nucleolar protein, component of the small subunit
(SSU) processome containing the U3 snoRNA that is involved
in processing of pre-18S rRNA"
/codon_start=1
/product="Utp15p"
/protein_id="NP_013811.1"
/db_xref="GI:6323740"
/db_xref="SGD:S000004699"
/db_xref="GeneID:855118"
/translation="MSTARPRIITSKAPLLPQQTTPEQRYWRQYTSAQLVKEHNSVTH
ISFNPQHPHDFAVTSSTRVQIFSSRTRQVIKTFSRFKDVVYSASFRSDGKLLCAGDAT
GLVSVYDSYNPRTILLSINASTHPTHVTKFHTQDNKILATASDDRVTRLWDISNAYEP
QLELTGATDYVRTLSFIPAAPHLVATGSYDGLIRLYDTRSSGSTPIYSLNHDQPVENV
IAVSPTQIVSCGGNNFKVWDLTSNKKLYERGNFNKAVTCLDYVENFDSPMQSALIASS
LDGHVKVFDPLDNFQVKFGWKFSGPVLSCAVSPSTAQGNRHLVAGLSSGLLAIRTKKK
EKRSSDKENAPASFNKNAKSNNFQRMMRGSEYQGDQEHIIHNDKVRSQRRMRAFERNI
NQFKWSEALDNAFVPGMAKELTLTVLQELRKRGKVRVALYGRDESTLEPLLNWCLKGI
EDVRSASIVADWVAVVLELYGNTLESSPVLQELMIDLKTKVRHEIHKSKEAQRIEGML
QLLTS"
gene 455825..457261
/gene="CTF13"
/locus_tag="YMR094W"
/db_xref="GeneID:855119"
mRNA 455825..457261
/gene="CTF13"
/locus_tag="YMR094W"
/product="Ctf13p"
/transcript_id="NM_001182594.1"
/db_xref="GI:296147211"
/db_xref="GeneID:855119"
CDS 455825..457261
/gene="CTF13"
/locus_tag="YMR094W"
/note="Subunit of the CBF3 complex, which binds to the CDE
III element of centromeres, bending the DNA upon binding,
and may be involved in sister chromatid cohesion during
mitosis"
/codon_start=1
/product="Ctf13p"
/protein_id="NP_013812.1"
/db_xref="GI:6323741"
/db_xref="SGD:S000004700"
/db_xref="GeneID:855119"
/translation="MPSFNPVRFLELPIDIRKEVYFHLDGNFCGAHPYPIDILYKSND
VELPGKPSYKRSKRSKKLLRYMYPVFATYLNIFEYSPQLIEKWLEYAFWLRYDCLVLD
CFKVNHLYDGTLIDALEWTYLDNELRLAYFNKASMLEVWYTFKEYKKWVIDSVAFDEL
DLLNVSNIQFNIDNLTPQLVDKCLSILEQKDLFATIGEVQFGQDEEVGEEKDVDVSGA
NSDENSSPSSTIKNKKRSASKRSHSDNGNVGATHNQLTSISVIRTIRSMESMKSLRKI
TVRGEKLYELLINFHGFRDNPGKTISYIVKRRINEIRLSRMNQISRTGLADFTRWDNL
QKLVLSRVAYIDLNSIVFPKNFKSLTMKRVSKIKWWNIEENILKELKVDKRTFKSLYI
KEDDSKFTKFFNLRHTRIKELDKSEINQITYLRCQAIVWLSFRTLNHIKLQNVSEVFN
NIIVPRALFDSKRVEIYRCEKISQVLVI"
gene complement(457285..457959)
/gene="SNO1"
/locus_tag="YMR095C"
/db_xref="GeneID:855120"
mRNA complement(457285..457959)
/gene="SNO1"
/locus_tag="YMR095C"
/product="Sno1p"
/transcript_id="NM_001182595.1"
/db_xref="GI:296147212"
/db_xref="GeneID:855120"
CDS complement(457285..457959)
/gene="SNO1"
/locus_tag="YMR095C"
/EC_number="2.6.-.-"
/note="Protein of unconfirmed function, involved in
pyridoxine metabolism; expression is induced during
stationary phase; forms a putative glutamine
amidotransferase complex with Snz1p, with Sno1p serving as
the glutaminase"
/codon_start=1
/product="Sno1p"
/protein_id="NP_013813.1"
/db_xref="GI:6323742"
/db_xref="SGD:S000004701"
/db_xref="GeneID:855120"
/translation="MHKTHSTMSGKSMKVIGVLALQGAFLEHTNHLKRCLAENDYGIK
IEIKTVKTPEDLAQCDALIIPGGESTSMSLIAQRTGLYPCLYEFVHNPEKVVWGTCAG
LIFLSAQLENESALVKTLGVLKVDVRRNAFGRQAQSFTQKCDFSNFIPGCDNFPATFI
RAPVIERILDPIAVKSLYELPVNGKDVVVAATQNHNILVTSFHPELADSDTRFHDWFI
RQFVSN"
gene 458408..459301
/gene="SNZ1"
/locus_tag="YMR096W"
/db_xref="GeneID:855121"
mRNA 458408..459301
/gene="SNZ1"
/locus_tag="YMR096W"
/product="Snz1p"
/transcript_id="NM_001182596.1"
/db_xref="GI:296147213"
/db_xref="GeneID:855121"
CDS 458408..459301
/gene="SNZ1"
/locus_tag="YMR096W"
/note="Protein involved in vitamin B6 biosynthesis; member
of a stationary phase-induced gene family; coregulated
with SNO1; interacts with Sno1p and with Yhr198p, perhaps
as a multiprotein complex containing other Snz and Sno
proteins"
/codon_start=1
/product="Snz1p"
/protein_id="NP_013814.1"
/db_xref="GI:6323743"
/db_xref="SGD:S000004702"
/db_xref="GeneID:855121"
/translation="MTGEDFKIKSGLAQMLKGGVIMDVVTPEQAKIAEKSGACAVMAL
ESIPADMRKSGKVCRMSDPKMIKDIMNSVSIPVMAKVRIGHFVEAQIIEALEVDYIDE
SEVLTPADWTHHIEKDKFKVPFVCGAKDLGEALRRINEGAAMIRTKGEAGTGDVSEAV
KHIRRITEEIKACQQLKSEDDIAKVAEEMRVPVSLLKDVLEKGKLPVVNFAAGGVATP
ADAALLMQLGCDGVFVGSGIFKSSNPVRLATAVVEATTHFDNPSKLLEVSSDLGELMG
GVSIESISHASNGVRLSEIGW"
gene complement(459424..460527)
/gene="MTG1"
/locus_tag="YMR097C"
/db_xref="GeneID:855122"
mRNA complement(459424..460527)
/gene="MTG1"
/locus_tag="YMR097C"
/product="Mtg1p"
/transcript_id="NM_001182597.1"
/db_xref="GI:296147214"
/db_xref="GeneID:855122"
CDS complement(459424..460527)
/gene="MTG1"
/locus_tag="YMR097C"
/note="Putative GTPase peripheral to the mitochondrial
inner membrane, essential for respiratory competence,
likely functions in assembly of the large ribosomal
subunit, has homologs in plants and animals"
/codon_start=1
/product="Mtg1p"
/protein_id="NP_013815.1"
/db_xref="GI:6323744"
/db_xref="SGD:S000004703"
/db_xref="GeneID:855122"
/translation="MHINVRGTRKIISNVSSFTPRYEFPKYSMPLTDFKGHQVKALKT
FEKLLPQMNMIIELRDIRAPLSTRNVVFDRIARKEHDVMKLVVYTRKDLMPGNKPYIG
KLKNWHEELGEKFILLDCRNKTDVRNLLKILEWQNYELETNGGYLPMGYRALITGMPN
VGKSTLINSLRTIFHNQVNMGRKFKKVAKTGAEAGVTRATSEVIRVTSRNTESRNEIY
LIDTPGIGVPGRVSDHNRMLGLALCGSVKNNLVDPIFQADYLLYLMNLQNLNDGRTEL
YPGSTNSPTNDIYDVLRRLQVNKSQNEKSTAIEWTNKWRLHGKGIIFDPEVLLNNDEF
SYKNYVNDQLEKLGDLSYEGLSNKLKGNPNQVF"
gene complement(460771..462609)
/gene="ATP25"
/locus_tag="YMR098C"
/db_xref="GeneID:855123"
mRNA complement(460771..462609)
/gene="ATP25"
/locus_tag="YMR098C"
/product="Atp25p"
/transcript_id="NM_001182598.1"
/db_xref="GI:296147215"
/db_xref="GeneID:855123"
CDS complement(460771..462609)
/gene="ATP25"
/locus_tag="YMR098C"
/note="Mitochondrial protein required for the stability of
Oli1p (Atp9p) mRNA and for the Oli1p ring formation;
YMR098C is not an essential gene"
/codon_start=1
/product="Atp25p"
/protein_id="NP_013816.1"
/db_xref="GI:6323745"
/db_xref="SGD:S000004704"
/db_xref="GeneID:855123"
/translation="MNKFCLLPFHGKRIGVANIPFTILFKKGPYFLHSHITAVYYSTK
GKNDSHEQSRVSKKSTFTPLETPWYLRIVDNEKELMEGKKNNHHTMNKELEIPKTSPN
SLRKIADLLTGKLGLDDFLVFDLRKKSPNSVSAVNKLGDFMVICTARSTKHCHKSFLE
LNKFLKHEFCSSAYVEGNFNERQESRRKRRLARKSNLSKLLGRSSECSAKDLNSEAWY
MIDCRVDGIFVNILTQRRRNELNLEELYAPENEKSKFQNIDSGNVPTISGVNEISSNN
NILLGLRRLAQQRRRYSTINPNGLSNLRYFLQKEDFKGANKIIQSSSGTETHNIRTLE
HVKNTLKDLVGQERKVDVVQWKSLFDEHSTFLTINQSAAYWPLRLEYAILLNKADPQF
YSDRVFLKDYLLLKKSLGQELIREDLIALLEMVLKTQHSSHSYFNLVKQNRVIIRALN
LFKGLQTEDDGSVVYDEVVISLLLNSMVADERVKLRSLYETIDHIFQTFGDKLTSGMI
VSILQNLAKIKDWNKLLQVWEAITPTEGEGQDKRPWNEFINVINQSGDSHVISKIVNN
GHLLWIRRLNVNVTPELCNSIKALLKTAGMENSTLEEFLVRGTNNQ"
LTR complement(463128..463461)
/note="Ty1 LTR"
/db_xref="SGD:S000007114"
gene 463554..463625
/locus_tag="tD(GUC)M"
/db_xref="GeneID:855124"
tRNA 463554..463625
/locus_tag="tD(GUC)M"
/product="tRNA-Asp"
/note="Aspartate tRNA (tRNA-Asp), predicted by tRNAscan-SE
analysis"
/db_xref="SGD:S000006543"
/db_xref="GeneID:855124"
gene complement(463934..464827)
/locus_tag="YMR099C"
/db_xref="GeneID:855125"
mRNA complement(463934..464827)
/locus_tag="YMR099C"
/product="glucose-6-phosphate 1-epimerase"
/transcript_id="NM_001182599.1"
/db_xref="GI:296147216"
/db_xref="GeneID:855125"
CDS complement(463934..464827)
/locus_tag="YMR099C"
/note="Glucose-6-phosphate 1-epimerase (hexose-6-phosphate
mutarotase), likely involved in carbohydrate metabolism;
GFP-fusion protein localizes to both the nucleus and
cytoplasm and is induced in response to the DNA-damaging
agent MMS"
/codon_start=1
/product="glucose-6-phosphate 1-epimerase"
/protein_id="NP_013817.1"
/db_xref="GI:6323746"
/db_xref="SGD:S000004705"
/db_xref="GeneID:855125"
/translation="MPIKETDKEVVLTHPADETTSVHILKYGATVYSWKLKSEEQLWL
STAAKLDGSKPVRGGIPLVFPVFGKNSTDEHLSKLPQHGLARNSTWEFLGQTKENPPT
VQFGLKPEIANPELTKLWPMDYLLILTVELGSDYLKTAIEVENTSSSKELKFNWLFHT
YFRIEDIEGTMVSNLAGMKLYDQLLKESYVDKHPVVTFNQETDVIYQNVSAERAIQIV
DKGVQIHTLKRYNLPDTVVWNPWIEKSQGMADFEPKTGYQQMICIEPGHVHDFISLAP
GKKWNAYQLLCKEELKYQAIQ"
gene 466300..468162
/gene="MUB1"
/locus_tag="YMR100W"
/db_xref="GeneID:855126"
mRNA 466300..468162
/gene="MUB1"
/locus_tag="YMR100W"
/product="Mub1p"
/transcript_id="NM_001182600.1"
/db_xref="GI:296147217"
/db_xref="GeneID:855126"
CDS 466300..468162
/gene="MUB1"
/locus_tag="YMR100W"
/note="MYND domain-containing protein required for
ubiquitination and turnover of Rpn4p; interacts with Ubr2p
(E3) and indirectly with Rad6p (E2); short-lived protein
degraded in a Ubr2p/Rad6p dependent manner; similar to the
A. nidulans samB gene"
/codon_start=1
/product="Mub1p"
/protein_id="NP_013818.1"
/db_xref="GI:6323747"
/db_xref="SGD:S000004706"
/db_xref="GeneID:855126"
/translation="MRDSNHRSLTSNKPIVTITSTVYDRRALDINSSIPLINSLNYLT
YLTSNSSKVRETVANDGALERLVSILRSCHLSLFELLDLDLENFNEHENIKDLWKEKR
LALCAWKWTLTFQCLVLTGTRGTEQIRKKVVMSGVLSVLVTVLDNYLLYHKNYDFIKD
QTMTFDFKGITTETMYKFMRKDENETYQQYIEFITGQDKLKLSTDKNFLNERLVAPSM
TIPTDFSDIWGRFADLASNFEPDQERHDDDIDIDSEVESENFDAHKNFFSQPDINRPT
ISTPREFFLGRIVPKQDDVIWSLQLLAFVSKYTYMKSTLQNVELVESLSFRSMAYKIK
QRISEENDLEEQERDVTVKLSSLYPYLSKNPENNSKVKALDTSKMDPFFKELEELSNR
CQQEEQNEICNNHCPVLNLFERYRVPKPSDDNAYGKDKERINLRKKISDNFERRWSYD
KMKKELTNIVYKNKVLTNVVNIFPLVEKYTVSAENTHDVIYWSSVIMRNSCRKNEILG
VRQCANFSCGKWEDFPRQFAKCRRCKRTKYCSRKCQLKAWGYHRYWCHEVGSSHMRST
NTTTGVNTPNEPSSLNATATTAADVSNSTSTFTPNISTTVPDEISNRDENSIPE"
rep_origin 468179..468469
/note="ARS1316;
Autonomously Replicating Sequence"
/db_xref="SGD:S000118372"
gene complement(468445..469476)
/gene="SRT1"
/locus_tag="YMR101C"
/db_xref="GeneID:855127"
mRNA complement(468445..469476)
/gene="SRT1"
/locus_tag="YMR101C"
/product="Srt1p"
/transcript_id="NM_001182601.1"
/db_xref="GI:296147218"
/db_xref="GeneID:855127"
CDS complement(468445..469476)
/gene="SRT1"
/locus_tag="YMR101C"
/EC_number="2.5.1.-"
/note="Cis-prenyltransferase involved in synthesis of
long-chain dolichols (19-22 isoprene units; as opposed to
Rer2p which synthesizes shorter-chain dolichols);
localizes to lipid bodies; transcription is induced during
stationary phase"
/codon_start=1
/product="Srt1p"
/protein_id="NP_013819.1"
/db_xref="GI:6323748"
/db_xref="SGD:S000004707"
/db_xref="GeneID:855127"
/translation="MKMPSIIQIQFVALKRLLVETKEQMCFAVKSIFQRVFAWVMSLS
LFSWFYVNLQNILIKALRVGPVPEHVSFIMDGNRRYAKSRRLPVKKGHEAGGLTLLTL
LYICKRLGVKCVSAYAFSIENFNRPKEEVDTLMNLFTVKLDEFAKRAKDYKDPLYGSK
IRIVGDQSLLSPEMRKKIKKVEEITQDGDDFTLFICFPYTSRNDMLHTIRDSVEDHLE
NKSPRINIRKFTNKMYMGFHSNKCELLIRTSGHRRLSDYMLWQVHENATIEFSDTLWP
NFSFFAMYLMILKWSFFSTIQKYNEKNHSLFEKIHESVPSIFKKKKTAMSLYNFPNPP
ISVSVTGDE"
gene complement(469848..472352)
/locus_tag="YMR102C"
/db_xref="GeneID:855128"
mRNA complement(469848..472352)
/locus_tag="YMR102C"
/product="hypothetical protein"
/transcript_id="NM_001182602.1"
/db_xref="GI:296147219"
/db_xref="GeneID:855128"
CDS complement(469848..472352)
/locus_tag="YMR102C"
/note="hypothetical protein; transcription is activated by
paralogous transcription factors Yrm1p and Yrr1p along
with genes involved in multidrug resistance; mutant shows
increased resistance to azoles; YMR102C is not an
essential gene"
/codon_start=1
/product="hypothetical protein"
/protein_id="NP_013820.1"
/db_xref="GI:6323749"
/db_xref="SGD:S000004708"
/db_xref="GeneID:855128"
/translation="MTNMAEDKTSISKVHSEFSNSSNTTGSEEESRSHQESFDGESSS
GESKSKSKLNLEYSADIEPLKFRMTKTNNTNDKLKYSNNGNATDSFMRLKEHLQRGNT
LNSNLRVNEFYPFNSIDTEQFENYLREPKYIKMLKRRKNLKQFRRLFLAQELMAYEGE
TVTSTSKSSEPTSKAIWSTKFSRDGKFMATGSKDGKIRIWKVIGSPVERAELDSSAES
NKEARAKSMRIKQQVSSLNNPKEKQFLDSATEKYEEKEKLLNLYAPVFHPTPLRLYKE
HVQDVLDINWSKNNFILSASMDKTVKLWHPDRKNSLKTFIHPDFVTCVEFHPTDDRFF
ISGCLDHKCRLWSILDDEVSFEYDCQDLITSVTLSPEEGKYTIIGTFNGYVHILMTRG
LTPVSSFHVADRQTQEQNAHVMVTETDSKIRHGPRVTGLQAFRSQLDNSFRLVVTSND
SRIRIFDLEQRKLLEVLKGFHSGSSQHKAQLSIWHGQPIVVNSSDDHWVYGWRLKSSD
RENDQDEPKRKPKGLARSGSLRSIFSKSMSRSSSQNNEEKPHHHLKLTNLLPLPHHSN
DHYIKNTDYISFHAHNAPVTCVSIAPPETSKTLSLSNDVICELSLEFFQTSDSFDVLS
RSNDDGIMSDVESSLGYNSKPGSISNASATSAIPDVVDAIGTILISTDNVGTIRVFRA
DMPSVIRKRVLLKLEEYNREVRRRFNSSDSLHSLSRSFNSRAKSNLAGQPAAAYTNTG
KGYATGRGYSNICPKSSTSLKTLGSNAQPRTPRESMSSIFSNAHGPTTPTSAMNLPIR
CNVCNGSRFEAFSGANDQQDRNYYCVDCGTVVNNFR"
gene complement(473420..475453)
/gene="YPK2"
/locus_tag="YMR104C"
/gene_synonym="YKR2"
/db_xref="GeneID:855130"
mRNA complement(473420..475453)
/gene="YPK2"
/locus_tag="YMR104C"
/gene_synonym="YKR2"
/product="Ypk2p"
/transcript_id="NM_001182604.1"
/db_xref="GI:296147220"
/db_xref="GeneID:855130"
CDS complement(473420..475453)
/gene="YPK2"
/locus_tag="YMR104C"
/gene_synonym="YKR2"
/EC_number="2.7.11.1"
/note="Protein kinase with similarity to serine/threonine
protein kinase Ypk1p; functionally redundant with YPK1 at
the genetic level; participates in a signaling pathway
required for optimal cell wall integrity; homolog of
mammalian kinase SGK"
/codon_start=1
/product="Ypk2p"
/protein_id="NP_013822.1"
/db_xref="GI:6323751"
/db_xref="SGD:S000004710"
/db_xref="GeneID:855130"
/translation="MHSWRISKFKLGRSKEDDGSSEDENEKSWGNGLFHFHHGEKHHD
GSPKNHNHEHEHHIRKINTNETLPSSLSSPKLRNDASFKNPSGIGNDNSKASERKASQ
SSTETQGPSSESGLMTVKVYSGKDFTLPFPITSNSTILQKLLSSGILTSSSNDASEVA
AIMRQLPRYKRVDQDSAGEGLIDRAFATKFIPSSILLPGSTNSSPLLYFTIEFDNSIT
TISPDMGTMEQPVFNKISTFDVTRKLRFLKIDVFARIPSLLLPSKNWQQEIGEQDEVL
KEILKKINTNQDIHLDSFHLPLNLKIDSAAQIRLYNHHWISLERGYGKLNITVDYKPS
KNKPLSIDDFDLLKVIGKGSFGKVMQVRKKDTQKIYALKALRKAYIVSKCEVTHTLAE
RTVLARVDCPFIVPLKFSFQSPEKLYLVLAFINGGELFYHLQHEGRFSLARSRFYIAE
LLCALDSLHKLDVIYRDLKPENILLDYQGHIALCDFGLCKLNMKDNDKTDTFCGTPEY
LAPEILLGQGYTKTVDWWTLGILLYEMMTGLPPYYDENVPVMYKKILQQPLLFPDGFD
PAAKDLLIGLLSRDPSRRLGVNGTDEIRNHPFFKDISWKKLLLKGYIPPYKPIVKSEI
DTANFDQEFTKEKPIDSVVDEYLSASIQKQFGGWTYIGDEQLGDSPSQGRSIS"
gene complement(475897..477606)
/gene="PGM2"
/locus_tag="YMR105C"
/gene_synonym="GAL5"
/db_xref="GeneID:855131"
mRNA complement(475897..477606)
/gene="PGM2"
/locus_tag="YMR105C"
/gene_synonym="GAL5"
/product="phosphoglucomutase PGM2"
/transcript_id="NM_001182605.1"
/db_xref="GI:296147221"
/db_xref="GeneID:855131"
CDS complement(475897..477606)
/gene="PGM2"
/locus_tag="YMR105C"
/gene_synonym="GAL5"
/EC_number="5.4.2.2"
/note="Phosphoglucomutase; catalyzes the conversion from
glucose-1-phosphate to glucose-6-phosphate, which is a key
step in hexose metabolism; functions as the acceptor for a
Glc-phosphotransferase; protein abundance increases in
response to DNA replication stress"
/codon_start=1
/product="phosphoglucomutase PGM2"
/protein_id="NP_013823.1"
/db_xref="GI:6323752"
/db_xref="SGD:S000004711"
/db_xref="GeneID:855131"
/translation="MSFQIETVPTKPYEDQKPGTSGLRKKTKVFKDEPNYTENFIQSI
MEAIPEGSKGATLVVGGDGRYYNDVILHKIAAIGAANGIKKLVIGQHGLLSTPAASHI
MRTYEEKCTGGIILTASHNPGGPENDMGIKYNLSNGGPAPESVTNAIWEISKKLTSYK
IIKDFPELDLGTIGKNKKYGPLLVDIIDITKDYVNFLKEIFDFDLIKKFIDNQRSTKN
WKLLFDSMNGVTGPYGKAIFVDEFGLPADEVLQNWHPSPDFGGMHPDPNLTYASSLVK
RVDREKIEFGAASDGDGDRNMIYGYGPSFVSPGDSVAIIAEYAAEIPYFAKQGIYGLA
RSFPTSGAIDRVAKAHGLNCYEVPTGWKFFCALFDAKKLSICGEESFGTGSNHVREKD
GVWAIMAWLNILAIYNKHHPENEASIKTIQNEFWAKYGRTFFTRYDFEKVETEKANKI
VDQLRAYVTKSGVVNSAFPADESLKVTDCGDFSYTDLDGSVSDHQGLYVKLSNGARFV
LRLSGTGSSGATIRLYIEKYCDDKSQYQKTAEEYLKPIINSVIKFLNFKQVLGTEEPT
VRT"
rep_origin 477606..478301
/note="ARS1317;
Putative replication origin, identified in multiple array
studies, not yet confirmed by plasmid-based assay"
/db_xref="SGD:S000130188"
gene 478064..478258
/locus_tag="YMR105W-A"
/db_xref="GeneID:1466500"
mRNA 478064..478258
/locus_tag="YMR105W-A"
/product="hypothetical protein"
/transcript_id="NM_001184614.1"
/db_xref="GI:296147222"
/db_xref="GeneID:1466500"
CDS 478064..478258
/locus_tag="YMR105W-A"
/codon_start=1
/product="hypothetical protein"
/protein_id="NP_878142.1"
/db_xref="GI:33438854"
/db_xref="SGD:S000028692"
/db_xref="GeneID:1466500"
/translation="MILVHTGNVLYPRFIVVAFTFEQRQGGRCKGGKATCMASVQSYK
VTMQISSMTIIYPLFIFFSL"
gene complement(478301..480190)
/gene="YKU80"
/locus_tag="YMR106C"
/gene_synonym="HDF2"
/db_xref="GeneID:855132"
mRNA complement(478301..480190)
/gene="YKU80"
/locus_tag="YMR106C"
/gene_synonym="HDF2"
/product="Yku80p"
/transcript_id="NM_001182606.1"
/db_xref="GI:296147223"
/db_xref="GeneID:855132"
CDS complement(478301..480190)
/gene="YKU80"
/locus_tag="YMR106C"
/gene_synonym="HDF2"
/note="Subunit of the telomeric Ku complex
(Yku70p-Yku80p), involved in telomere length maintenance,
structure and telomere position effect; relocates to sites
of double-strand cleavage to promote nonhomologous end
joining during DSB repair"
/codon_start=1
/product="Yku80p"
/protein_id="NP_013824.1"
/db_xref="GI:6323753"
/db_xref="SGD:S000004712"
/db_xref="GeneID:855132"
/translation="MSSESTTFIVDVSPSMMKNNNVSKSMAYLEYTLLNKSKKSRKTD
WISCYLANCPVSENSQEIPNVFQIQSFLAPVTTTATIGFIKRLKQYCDQHSHDSSNEG
LQSMIQCLLVVSLDIKQQFQARKILKQIVVFTDNLDDLDITDEEIDLLTEELSTRIIL
IDCGKDTQEERKKSNWLKLVEAIPNSRIYNMNELLVEITSPATSVVKPVRVFSGELRL
GADILSTQTSNPSGSMQDENCLCIKVEAFPATKAVSGLNRKTAVEVEDSQKKERYVGV
KSIIEYEIHNEGNKKNVSEDDQSGSSYIPVTISKDSVTKAYRYGADYVVLPSVLVDQT
VYESFPGLDLRGFLNREALPRYFLTSESSFITADTRLGCQSDLMAFSALVDVMLENRK
IAVARYVSKKDSEVNMCALCPVLIEHSNINSEKKFVKSLTLCRLPFAEDERVTDFPKL
LDRTTTSGVPLKKETDGHQIDELMEQFVDSMDTDELPEIPLGNYYQPIGEVTTDTTLP
LPSLNKDQEENKKDPLRIPTVFVYRQQQVLLEWIHQLMINDSREFEIPELPDSLKNKI
SPYTHKKFDSTKLVEVLGIKKVDKLKLDSELKTELEREKIPDLETLLKRGEQHSRGSP
NNSNN"
gene complement(480621..480693)
/locus_tag="tK(CUU)M"
/db_xref="GeneID:855133"
tRNA complement(480621..480693)
/locus_tag="tK(CUU)M"
/product="tRNA-Lys"
/note="Lysine tRNA (tRNA-Lys), predicted by tRNAscan-SE
analysis; a small portion is imported into mitochondria
via interaction with mt lysyl-tRNA synthetase Msk1p and is
necessary to decode AAG codons at high temperature, when
base modification of mt-encoded tRNA-Lys is reduced"
/db_xref="SGD:S000006627"
/db_xref="GeneID:855133"
LTR complement(481214..481547)
/note="Ty1 LTR"
/db_xref="SGD:S000007115"
LTR 481571..481808
/note="Ty1 LTR"
/db_xref="SGD:S000007122"
gene 483014..483361
/gene="SPG4"
/locus_tag="YMR107W"
/db_xref="GeneID:855134"
mRNA 483014..483361
/gene="SPG4"
/locus_tag="YMR107W"
/product="Spg4p"
/transcript_id="NM_001182607.1"
/db_xref="GI:296147224"
/db_xref="GeneID:855134"
CDS 483014..483361
/gene="SPG4"
/locus_tag="YMR107W"
/note="Protein required for survival at high temperature
during stationary phase; not required for growth on
nonfermentable carbon sources"
/codon_start=1
/product="Spg4p"
/protein_id="NP_013825.1"
/db_xref="GI:6323754"
/db_xref="SGD:S000004713"
/db_xref="GeneID:855134"
/translation="MGSFWDAFAVYDKKKHADPSVYGGNHNNTGDSKTQVMFSKEYRQ
PRTHQQENLQSMRRSSIGSQDSSDVEDVKEGRLPAEVEIPKNVDISNMSQGEFLRLYE
SLRRGEPDNKVNR"
gene 484084..486147
/gene="ILV2"
/locus_tag="YMR108W"
/gene_synonym="SMR1; THI1"
/db_xref="GeneID:855135"
mRNA 484084..486147
/gene="ILV2"
/locus_tag="YMR108W"
/gene_synonym="SMR1; THI1"
/product="acetolactate synthase catalytic subunit"
/transcript_id="NM_001182608.1"
/db_xref="GI:296147225"
/db_xref="GeneID:855135"
CDS 484084..486147
/gene="ILV2"
/locus_tag="YMR108W"
/gene_synonym="SMR1; THI1"
/EC_number="2.2.1.6"
/note="Acetolactate synthase, catalyses the first common
step in isoleucine and valine biosynthesis and is the
target of several classes of inhibitors, localizes to the
mitochondria; expression of the gene is under general
amino acid control"
/codon_start=1
/product="acetolactate synthase catalytic subunit"
/protein_id="NP_013826.1"
/db_xref="GI:6323755"
/db_xref="SGD:S000004714"
/db_xref="GeneID:855135"
/translation="MIRQSTLKNFAIKRCFQHIAYRNTPAMRSVALAQRFYSSSSRYY
SASPLPASKRPEPAPSFNVDPLEQPAEPSKLAKKLRAEPDMDTSFVGLTGGQIFNEMM
SRQNVDTVFGYPGGAILPVYDAIHNSDKFNFVLPKHEQGAGHMAEGYARASGKPGVVL
VTSGPGATNVVTPMADAFADGIPMVVFTGQVPTSAIGTDAFQEADVVGISRSCTKWNV
MVKSVEELPLRINEAFEIATSGRPGPVLVDLPKDVTAAILRNPIPTKTTLPSNALNQL
TSRAQDEFVMQSINKAADLINLAKKPVLYVGAGILNHADGPRLLKELSDRAQIPVTTT
LQGLGSFDQEDPKSLDMLGMHGCATANLAVQNADLIIAVGARFDDRVTGNISKFAPEA
RRAAAEGRGGIIHFEVSPKNINKVVQTQIAVEGDATTNLGKMMSKIFPVKERSEWFAQ
INKWKKEYPYAYMEETPGSKIKPQTVIKKLSKVANDTGRHVIVTTGVGQHQMWAAQHW
TWRNPHTFITSGGLGTMGYGLPAAIGAQVAKPESLVIDIDGDASFNMTLTELSSAVQA
GTPVKILILNNEEQGMVTQWQSLFYEHRYSHTHQLNPDFIKLAEAMGLKGLRVKKQEE
LDAKLKEFVSTKGPVLLEVEVDKKVPVLPMVAGGSGLDEFINFDPEVERQQTELRHKR
TGGKH"
gene 486587..490246
/gene="MYO5"
/locus_tag="YMR109W"
/db_xref="GeneID:855136"
mRNA 486587..490246
/gene="MYO5"
/locus_tag="YMR109W"
/product="Myo5p"
/transcript_id="NM_001182609.1"
/db_xref="GI:296147226"
/db_xref="GeneID:855136"
CDS 486587..490246
/gene="MYO5"
/locus_tag="YMR109W"
/note="One of two type I myosins; contains proline-rich
tail homology 2 (TH2) and SH3 domains; MYO5 deletion has
little effect on growth, but myo3 myo5 double deletion
causes severe defects in growth and actin cytoskeleton
organization"
/codon_start=1
/product="myosin 5"
/protein_id="NP_013827.1"
/db_xref="GI:6323756"
/db_xref="SGD:S000004715"
/db_xref="GeneID:855136"
/translation="MAILKRGARKKVHQEPAKRSANIKKATFDSSKKKEVGVSDLTLL
SKISDEAINENLKKRFLNATIYTYIGHVLISVNPFRDLGIYTDAVMNEYKGKNRLEVP
PHVFAIAESMYYNMKSYNENQCVIISGESGAGKTEAAKRIMQYIAAASSTHTESIGKI
KDMVLATNPLLESFGCAKTLRNNNSSRHGKYLEIKFNNQFEPCAGNITNYLLEKQRVV
SQIKNERNFHIFYQFTKGASDAYRQTFGVQKPEQYVYTAAAGCISAETIDDLQDYQET
LKAMRVIGLGQEEQDQIFRMLAAILWIGNVSFIENEEGNAQVRDTSVTDFVAYLLQID
SQLLIKSLVERIMETNHGMKRGSVYHVPLNIVQADAVRDALAKAIYNNLFDWIVSRVN
KSLQAFPGAEKSIGILDIYGFEIFEHNSFEQICINYVNEKLQQIFIQLTLKSEQETYE
REKIQWTPIKYFDNKVVCDLIEARRPPGIFAAMNDSVATAHADSNAADQAFAQRLNLF
TTNPHFDLRSNKFVIKHYAGDVTYDIDGITDKNKDQLQKDLVELIGTTTNTFLATIFP
DTVDRESKRRPPTAGDKIIKSANDLVETLSKAQPSYIRTIKPNETKSPNDYDDRQVLH
QIKYLGLQENVRIRRAGFAYRQVFEKFVERFYLLSPHCSYAGDYTWQGDTLDAVKYIL
QDSSIPQQEYQLGVTSVFIKTPETLFALEHMRDRYWHNMAARIQRAWRRFLQRRIDAA
TKIQRTIRERKEGNKYEKLRDYGTKVLGGRKERRSMSLLGYRAFMGDYLSCNESKSKG
AYIKRQVSIKEKVIFSIHGEALHTKFGRSAQRLKKTFLLTPTTLYIVGQTLVQNAMTY
TQDYKIDVRNIQAVSLTNLQDDWVAIKLASSGQPDPLINTYFKTELITHLKRLNDKIQ
IKIGSAIEYQKKPGKLHSVKCQINESAPKYGDIYKSSTISVRRGNPPNSQVHKKPRKK
SSISSGYHASSSQATRRPVSIAAAQHVPTAPASRHSKKPAPPPPGMQNKAATRRSVPN
PASTLTASQSNARPSPPTAATRATPAATPAAAAMGSGRQANIPPPPPPPPPSSKPKEP
MFEAAYDFPGSGSPSELPLKKGDVIYITREEPSGWSLGKLLDGSKEGWVPTAYMKPHS
GNNNIPTPPQNRDVPKPVLNSVQHDNTSANVIPAAAQASLGDGLANALAARANKMRLE
SDDEEANEDEEEDDW"
gene complement(490394..491992)
/gene="HFD1"
/locus_tag="YMR110C"
/db_xref="GeneID:855137"
mRNA complement(490394..491992)
/gene="HFD1"
/locus_tag="YMR110C"
/product="Hfd1p"
/transcript_id="NM_001182610.1"
/db_xref="GI:296147227"
/db_xref="GeneID:855137"
CDS complement(490394..491992)
/gene="HFD1"
/locus_tag="YMR110C"
/EC_number="1.2.1.-"
/note="Hexadecenal dehydrogenase; involved in the
conversion of sphingosine 1-phosphate breakdown product
hexadecenal to hexadecenoic acid; located in the
mitochondrial outer membrane and also in lipid particles;
has similarity to ALDH3A2, a human fatty aldehyde
dehydrogenase (FALDH) mutated in Sjogren-Larsson syndrome,
a neurocutaneous disorder"
/codon_start=1
/product="Hfd1p"
/protein_id="NP_013828.1"
/db_xref="GI:6323757"
/db_xref="SGD:S000004716"
/db_xref="GeneID:855137"
/translation="MSNDGSKILNYTPVSKIDEIVEISRNFFFEKQLKLSHENNPRKK
DLEFRQLQLKKLYYAVKDHEEELIDAMYKDFHRNKIESVLNETTKLMNDILHLIEILP
KLIKPRRVSDSSPPFMFGKTIVEKISRGSVLIIAPFNFPLLLAFAPLAAALAAGNTIV
LKPSELTPHTAVVMENLLTTAGFPDGLIQVVQGAIDETTRLLDCGKFDLIFYTGSPRV
GSIVAEKAAKSLTPCVLELGGKSPTFITENFKASNIKIALKRIFFGAFGNSGQICVSP
DYLLVHKSIYPKVIKECESVLNEFYPSFDEQTDFTRMIHEPAYKKAVASINSTNGSKI
VPSKISINSDTEDLCLVPPTIVYNIGWDDPLMKQENFAPVLPIIEYEDLDETINKIIE
EHDTPLVQYIFSDSQTEINRILTRLRSGDCVVGDTVIHVGITDAPFGGIGTSGYGNYG
GYYGFNTFSHERTIFKQPYWNDFTLFMRYPPNSAQKEKLVRFAMERKPWFDRNGNNKW
GLRQYFSLSAAVILISTIYAHCSS"
gene complement(492404..493792)
/locus_tag="YMR111C"
/db_xref="GeneID:855138"
mRNA complement(492404..493792)
/locus_tag="YMR111C"
/product="hypothetical protein"
/transcript_id="NM_001182611.1"
/db_xref="GI:296147228"
/db_xref="GeneID:855138"
CDS complement(492404..493792)
/locus_tag="YMR111C"
/note="hypothetical protein; green fluorescent protein
(GFP)-fusion protein localizes to the nucleus; YMR111C is
not an essential gene; forms nuclear foci upon DNA
replication stress"
/codon_start=1
/product="hypothetical protein"
/protein_id="NP_013829.1"
/db_xref="GI:6323758"
/db_xref="SGD:S000004717"
/db_xref="GeneID:855138"
/translation="MPAREYNYVEGFGGYGSLDDDDSDRDSERRNHDLGQRTITTSPT
GVSRHAALNRYMIPGRINPLFRPTDAAQPPIVSTSTSASATEPTNRIGPGRIKETPET
NFNAFLIAQLTRMEEQNANLKEEISLMKKEQELFFLENQKKLEKGFKDINKYVEDVSA
MKEVFKEVVGIMTGERIRFIDHTGENVTPQEAARVGNPSTSTQAHQSQSRSTNWQEYS
MHASILAGDPRIKPEPGLSDFENGEYDGNESDENATTRNLPLNNPDSVSNADDSNNQL
DGTGNENDIRNRRGCVGTSYKLNRAIQNVTDAAREYFEGLPGQPSVLSLERRYGSTWR
RSAKERTLFTKRMTIIKRIIDIKDDPSKYGLSLPENKISRNQAIKVVENIRLGNNTFK
GHHCRLSMSQLYEYFSKKMDKLEDYSLTLKRRGKPRRIFLLEEREARLSLQQPHSIPN
SSTGTPEHDQDT"
gene complement(494100..494495)
/gene="MED11"
/locus_tag="YMR112C"
/db_xref="GeneID:855139"
mRNA complement(494100..494495)
/gene="MED11"
/locus_tag="YMR112C"
/product="Med11p"
/transcript_id="NM_001182612.1"
/db_xref="GI:296147229"
/db_xref="GeneID:855139"
CDS complement(494100..494495)
/gene="MED11"
/locus_tag="YMR112C"
/note="Subunit of the RNA polymerase II mediator complex;
associates with core polymerase subunits to form the RNA
polymerase II holoenzyme; essential protein"
/codon_start=1
/product="Med11p"
/protein_id="NP_013830.1"
/db_xref="GI:6323759"
/db_xref="SGD:S000004718"
/db_xref="GeneID:855139"
/translation="MQVLNTKSETKQENETMQPPYIQERLKSLNDIETQLCSMLQEAS
QVTFIFGELKRGNESVKPQFENHVKQFYERLDKSTTQLRKEIQLLDENVGTRLLPINV
NKKALGQDTEKMEEQLDLLSAILDPSKSK"
gene 494999..496282
/gene="FOL3"
/locus_tag="YMR113W"
/db_xref="GeneID:855140"
mRNA 494999..496282
/gene="FOL3"
/locus_tag="YMR113W"
/product="dihydrofolate synthase"
/transcript_id="NM_001182613.1"
/db_xref="GI:296147230"
/db_xref="GeneID:855140"
CDS 494999..496282
/gene="FOL3"
/locus_tag="YMR113W"
/EC_number="6.3.2.12"
/note="Dihydrofolate synthetase, involved in folic acid
biosynthesis; catalyzes the conversion of dihydropteroate
to dihydrofolate in folate coenzyme biosynthesis"
/codon_start=1
/product="dihydrofolate synthase"
/protein_id="NP_013831.1"
/db_xref="GI:6323760"
/db_xref="SGD:S000004719"
/db_xref="GeneID:855140"
/translation="MAIELGLSRITKLLEHLGNPQNSLRVLHIAGTNGKGSVCTYLSS
VLQQKSYQIGKFTTPHLVHVTDSITINNKPIPLERYQNIRLQLEALNKSHSLKCTEFE
LLTCTAFKYFYDVQCQWCVIEVGLGGRLDATNVIPGANKACCGITKISLDHESFLGNT
LSEISKEKAGIITEGVPFTVIDGTNEASVINVVKERCKALGSELSVTDSQLNGNMIDT
NSWGCFDLAKLPLNGEYQIFNLRVAMGMLDYLQMNELIDITKNEVSTRLAKVDWPGRL
YRMDYRFDKVSNRTVPILMDGAHNGSAAVELVKYLRKEYGNQPLTFVMAVTHGKNLEP
LLQPLLRPIDQVILTRFNNVEGMPWIHATDPEEIKDFILTQGYTKEIVIENDLHQVLP
SLAHVSDEQRRPIVVCGSLYLCGELLRIHNSHLRN"
gene complement(496343..497449)
/locus_tag="YMR114C"
/db_xref="GeneID:855141"
mRNA complement(496343..497449)
/locus_tag="YMR114C"
/product="hypothetical protein"
/transcript_id="NM_001182614.1"
/db_xref="GI:296147231"
/db_xref="GeneID:855141"
CDS complement(496343..497449)
/locus_tag="YMR114C"
/note="hypothetical protein; may interact with ribosomes,
based on co-purification experiments; green fluorescent
protein (GFP)-fusion protein localizes to the nucleus and
cytoplasm; YMR114C is not an essential gene"
/codon_start=1
/product="hypothetical protein"
/protein_id="NP_013832.1"
/db_xref="GI:6323761"
/db_xref="SGD:S000004720"
/db_xref="GeneID:855141"
/translation="MCGRFALAYDSGDLPQLLRDWNLPVNTPKDASSNSQHPHDEEDT
KDQPTVSKDIFKASYNISPTNYSAVYRPDTKAIQFMRWGLVPFWTKDVSQFKTYRTFN
ARLENLQESKMWMRPCEKKRCAVLMSGYFEWKTVGKKKTPYFISRRDGRLMFVAGMYD
YVEKDDLYTFTIITAQGPRELEWLHERMPCVLEPGTESWDAWMDVDKTTWSTEELVKL
LKPDYDESKLQFYQVTDDVGKTTNTGERLIKPLLKEDSDMFSVKREKEEALLENDNEQ
GIDNRGVKGDKSLKGEDVFNQKKSLKRNSYDGLKKNEEQEETTLPEEGSIGDRVKREE
ANLSPKREGNREKRNIVNMLGNQKDSRGKKKIKK"
gene 497704..499209
/gene="MGR3"
/locus_tag="YMR115W"
/gene_synonym="FMP24"
/db_xref="GeneID:855142"
mRNA 497704..499209
/gene="MGR3"
/locus_tag="YMR115W"
/gene_synonym="FMP24"
/product="Mgr3p"
/transcript_id="NM_001182615.1"
/db_xref="GI:296147232"
/db_xref="GeneID:855142"
CDS 497704..499209
/gene="MGR3"
/locus_tag="YMR115W"
/gene_synonym="FMP24"
/note="Subunit of the mitochondrial (mt) i-AAA protease
supercomplex, which degrades misfolded mitochondrial
proteins; forms a subcomplex with Mgr1p that binds to
substrates to facilitate proteolysis; required for growth
of cells lacking mtDNA"
/codon_start=1
/product="Mgr3p"
/protein_id="NP_013833.1"
/db_xref="GI:6323762"
/db_xref="SGD:S000004721"
/db_xref="GeneID:855142"
/translation="MLLQGMRLSQRLHKRHLFASKILTWTTNPAHIRHLHDIRPPASN
FNTQESAPIPESPANSPTRPQMAPKPNLKKKNRSLMYSIIGVSIVGLYFWFKSNSRKQ
KLPLSAQKVWKEAIWQESDKMDFNYKEALRRYIEALDECDRSHVDLLSDDYTRIELKI
AEMYEKLNMLEEAQNLYQELLSRFFEALNVPGKVDESERGEVLRKDLRILIKSLEINK
DIESGKRKLLQHLLLAQEEILSKSPELKEFFENRKKKLSMVKDINRDPNDDFKTFVSE
ENIKFDEQGYMILDLEKNSSAWEPFKEEFFTARDLYTAYCLSSKDIAAALSCKITSVE
WMVMADMPPGQILLSQANLGSLFYLQAEKLEADLNQLEQKKSKESNQELDMGTYIKAV
RFVRKNRDLCLERAQKCYDSVIAFAKRNRKIRFHVKDQLDPSIAQSIALSTYGMGVLS
LHEGVLAKAEKLFKDSITMAKETEFNELLAEAEKELEKTTVLKAAKKEGLN"
gene complement(499456..500688)
/gene="ASC1"
/locus_tag="YMR116C"
/gene_synonym="CPC2; NAD1"
/db_xref="GeneID:855143"
mRNA complement(join(499456..499878,500152..500688))
/gene="ASC1"
/locus_tag="YMR116C"
/gene_synonym="CPC2; NAD1"
/product="Asc1p"
/transcript_id="NM_001182616.1"
/db_xref="GI:296147233"
/db_xref="GeneID:855143"
CDS complement(join(499456..499878,500152..500688))
/gene="ASC1"
/locus_tag="YMR116C"
/gene_synonym="CPC2; NAD1"
/note="G-protein beta subunit and guanine nucleotide
dissociation inhibitor for Gpa2p; ortholog of RACK1 that
inhibits translation; core component of the small (40S)
ribosomal subunit; regulates P-body formation induced by
replication stress; represses Gcn4p in the absence of
amino acid starvation"
/codon_start=1
/product="Asc1p"
/protein_id="NP_013834.1"
/db_xref="GI:6323763"
/db_xref="SGD:S000004722"
/db_xref="GeneID:855143"
/translation="MASNEVLVLRGTLEGHNGWVTSLATSAGQPNLLLSASRDKTLIS
WKLTGDDQKFGVPVRSFKGHSHIVQDCTLTADGAYALSASWDKTLRLWDVATGETYQR
FVGHKSDVMSVDIDKKASMIISGSRDKTIKVWTIKGQCLATLLGHNDWVSQVRVVPNE
KADDDSVTIISAGNDKMVKAWNLNQFQIEADFIGHNSNINTLTASPDGTLIASAGKDG
EIMLWNLAAKKAMYTLSAQDEVFSLAFSPNRYWLAAATATGIKVFSLDPQYLVDDLRP
EFAGYSKAAEPHAVSLAWSADGQTLFAGYTDNVIRVWQVMTAN"
gene complement(499984..500072)
/locus_tag="snR24"
/db_xref="GeneID:9164952"
ncRNA complement(499984..500072)
/locus_tag="snR24"
/ncRNA_class="snoRNA"
/product="SNR24"
/note="C/D box small nucleolar RNA (snoRNA); commonly
referred to as U24; guides 2'-O-methylation of large
subunit (LSU) rRNA at positions C1437, C1449, and C1450"
/db_xref="SGD:S000007501"
/db_xref="GeneID:9164952"
gene complement(501250..501891)
/gene="SPC24"
/locus_tag="YMR117C"
/db_xref="GeneID:855144"
mRNA complement(501250..501891)
/gene="SPC24"
/locus_tag="YMR117C"
/product="Spc24p"
/transcript_id="NM_001182617.1"
/db_xref="GI:296147234"
/db_xref="GeneID:855144"
CDS complement(501250..501891)
/gene="SPC24"
/locus_tag="YMR117C"
/note="Component of the evolutionarily conserved
kinetochore-associated Ndc80 complex
(Ndc80p-Nuf2p-Spc24p-Spc25p); involved in chromosome
segregation, spindle checkpoint activity and kinetochore
clustering"
/codon_start=1
/product="Spc24p"
/protein_id="NP_013835.1"
/db_xref="GI:6323764"
/db_xref="SGD:S000004723"
/db_xref="GeneID:855144"
/translation="MSQKDNLLDNPVEFLKEVRESFDIQQDVDAMKRIRHDLDVIKEE
SEARISKEHSKVSESNKKLNAERINVAKLEGDLEYTNEESNEFGSKDELVKLLKDLDG
LERNIVSLRSELDEKMKLYLKDSEIISTPNGSKIKAKVIEPELEEQSAVTPEANENIL
KLKLYRSLGVILDLENDQVLINRKNDGNIDILPLDNNLSDFYKTKYIWERLGK"
gene complement(502144..502734)
/gene="SHH3"
/locus_tag="YMR118C"
/db_xref="GeneID:855145"
mRNA complement(502144..502734)
/gene="SHH3"
/locus_tag="YMR118C"
/product="protein SHH3"
/transcript_id="NM_001182618.1"
/db_xref="GI:296147235"
/db_xref="GeneID:855145"
CDS complement(502144..502734)
/gene="SHH3"
/locus_tag="YMR118C"
/note="Putative mitochondrial inner membrane hypothetical
protein; although similar to Sdh3p, Shh3p is not a
stoichiometric subunit of either succinate dehydrogenase
or of the TIM22 translocase"
/codon_start=1
/product="protein SHH3"
/protein_id="NP_013836.1"
/db_xref="GI:6323765"
/db_xref="SGD:S000004724"
/db_xref="GeneID:855145"
/translation="MKATIQRVTSVFGVPRASVFVPRISTPFILHNYISNGRMDLFSK
EFHNGRVSKSDLWSSNKEEELLVSQRKKRPISPHLTVYEPEMSWYLSSLHRISGVLLA
LGFYAFTITLGVTTIMGMDTTFQDLNKWYHEKMPKWSQWVAKGSAAYLFAFHFGNGIR
HLIWDMGYELTNRGVIKTGSIVLAGTLVLGTYLLAQ"
LTR 503192..503389
/note="Ty1 LTR"
/db_xref="SGD:S000007123"
rep_origin 503389..503771
/note="ARS1319;
Putative replication origin, identified in multiple array
studies, not yet confirmed by plasmid-based assay"
/db_xref="SGD:S000130189"
LTR 503771..504141
/note="Ty4 LTR"
/db_xref="SGD:S000007128"
LTR 504346..504677
/note="Ty1 LTR"
/db_xref="SGD:S000007124"
gene 504895..505008
/locus_tag="tL(CAA)M"
/db_xref="GeneID:855146"
tRNA join(504895..504932,504965..505008)
/locus_tag="tL(CAA)M"
/product="tRNA-Leu"
/note="Leucine tRNA (tRNA-Leu), predicted by tRNAscan-SE
analysis"
/db_xref="SGD:S000006644"
/db_xref="GeneID:855146"
gene 505333..507207
/gene="ASI1"
/locus_tag="YMR119W"
/db_xref="GeneID:855147"
mRNA 505333..507207
/gene="ASI1"
/locus_tag="YMR119W"
/product="putative ubiquitin-protein ligase ASI1"
/transcript_id="NM_001182619.1"
/db_xref="GI:296147236"
/db_xref="GeneID:855147"
CDS 505333..507207
/gene="ASI1"
/locus_tag="YMR119W"
/note="Putative integral membrane E3 ubiquitin ligase;
acts with Asi2p and Asi3p to ensure the fidelity of
SPS-sensor signalling by maintaining the dormant repressed
state of gene expression in the absence of inducing
signals; ASI1 has a paralog, ASI3, that arose from the
whole genome duplication"
/codon_start=1
/product="putative ubiquitin-protein ligase ASI1"
/protein_id="NP_013837.1"
/db_xref="GI:6323766"
/db_xref="SGD:S000004725"
/db_xref="GeneID:855147"
/translation="MNSSTSSENVFINSFSYLNQTSQAVISGNSTFANVINFPYRLGL
SFIGAVNLQYEQTVKSEEIPPTLRSVFDTIGFFFSPYAIFCFVIAIVLNRFVVFYAVL
NNGSRRTLPLWLSNVFHVSAVVVLAMVSLGPLTLGKDFKILGDPAFAQEKFLLNIFYA
FAYSYCVETIFTIMRNSSPLEGTDYSLFELSIQFYTMTNNNTKFLDSPDYIIDCSMAI
LSRILIHLVEIFRLRNYRLLFSTIMNLCHICYLGIRVKQGGWKSLPFSVKFRHFPKLF
SVSIICLSLLIFKLSCLIRWDPFGKSRNSCELLQFYPLSRNWKKYLNYTGEEDFSAMA
TKFALLLCSGTELMEKGIRREFPAINIPDNVNEKFFISGYLNELSKPYKENTSISFPK
KNSSILKQRFFLMFPKSIIWIMKKLVGQVFFGFRDNKDEDIPDNDPSKMLKITKTNSL
NNSAGHKEDIELELLNTSDDEYSEDYEPSEVESLGDSDEENLEEDSLIFNETRDALLD
LFSSEDNEVHTDYNWIMSTSRILQQKLLSDKTLTRASILDTKLSEVDETFGTESDFDL
SCAVCKVNERNTVLWPCRCFAICEDCRISLGLRGFSTCVCCRSKVHGYCKVHPVSDSK
"
gene complement(507502..509280)
/gene="ADE17"
/locus_tag="YMR120C"
/db_xref="GeneID:855149"
mRNA complement(507502..509280)
/gene="ADE17"
/locus_tag="YMR120C"
/product="bifunctional
phosphoribosylaminoimidazolecarboxamide
formyltransferase/IMP cyclohydrolase ADE17"
/transcript_id="NM_001182621.1"
/db_xref="GI:296147237"
/db_xref="GeneID:855149"
CDS complement(507502..509280)
/gene="ADE17"
/locus_tag="YMR120C"
/EC_number="2.1.2.3"
/EC_number="3.5.4.10"
/note="Enzyme of 'de novo' purine biosynthesis; contains
both 5-aminoimidazole-4-carboxamide ribonucleotide
transformylase and inosine monophosphate cyclohydrolase
activities; ADE17 has a paralog, ADE16, that arose from
the whole genome duplication; ade16 ade17 mutants require
adenine and histidine"
/codon_start=1
/product="bifunctional
phosphoribosylaminoimidazolecarboxamide
formyltransferase/IMP cyclohydrolase ADE17"
/protein_id="NP_013839.1"
/db_xref="GI:6323768"
/db_xref="SGD:S000004727"
/db_xref="GeneID:855149"
/translation="MANYTKTAILSVYDKTGLLDLARGLIEKNVRILASGGTARMIRD
AGFPIEDVSAITHAPEMLGGRVKTLHPAVHGGILARDIDSDEKDLKEQHIEKVDYVVC
NLYPFKETVAKVGVTIPEAVEEIDIGGVTLLRAAAKNHARVTILSDPKDYSEFLSELS
SNGEISQDLRNRLALKAFEHTADYDAAISDFFRKQYSEGQAQITLRYGANPHQKPAQA
YVSQQDSLPFKVLCGSPGYINLLDALNSWPLVKELSASLNLPAAASFKHVSPAGAAVG
IPLSDVEKQVYFVADIENLSPLACAYARARGADRMSSFGDWIALSNIVDVPTAKIISR
EVSDGVIAPGYEPEALAILSKKKGGKYCILQIDPNYVPEAVERRQVYGVTLEQKRNDA
IINQSTFKEIVSQNKNLTEQAIIDLTVATIAIKYTQSNSVCYARNGMVVGLGAGQQSR
IHCTRLAGDKADNWWFRQHPRVLEIKWAKGVKRPEKSNAIDLFVTGQIPTEEPELSEY
QSKFEEIPKPFTPEERKEWLSKLTNVSLSSDAFFPFPDNVYRAVKSGVKYIAAPSGSV
MDKVVFSAADSFDLVYVENPIRLFHH"
gene complement(509734..510348)
/gene="RPL15B"
/locus_tag="YMR121C"
/db_xref="GeneID:855150"
mRNA complement(509734..510348)
/gene="RPL15B"
/locus_tag="YMR121C"
/product="ribosomal 60S subunit protein L15B"
/transcript_id="NM_001182622.1"
/db_xref="GI:296147238"
/db_xref="GeneID:855150"
CDS complement(509734..510348)
/gene="RPL15B"
/locus_tag="YMR121C"
/note="Ribosomal 60S subunit protein L15B; binds to 5.8 S
rRNA; homologous to mammalian ribosomal protein L15, no
bacterial homolog; RPL15B has a paralog, RPL15A, that
arose from the whole genome duplication; relocalizes from
nucleus to nucleolus upon DNA replication stress"
/codon_start=1
/product="ribosomal 60S subunit protein L15B"
/protein_id="NP_013840.1"
/db_xref="GI:6323769"
/db_xref="SGD:S000004728"
/db_xref="GeneID:855150"
/translation="MGAYKYLEELERKKQSDVLRFLQRVRVWEYRQKNVIHRAARPTR
PDKARRLGYKAKQGFVIYRVRVRRGNRKRPVPKGATYGKPTNQGVNELKYQRSLRATA
EERVGRRAANLRVLNSYWVNQDSTYKYFEVILVDPQHKAIRRDARYNWICNPVHKHRE
ARGLTATGKKSRGINKGHKFNNTKAGRRKTWKRQNTLSLWRYRK"
gene 511315..511569
/locus_tag="YMR122W-A"
/db_xref="GeneID:855152"
mRNA 511315..511569
/locus_tag="YMR122W-A"
/product="hypothetical protein"
/transcript_id="NM_001184445.1"
/db_xref="GI:296147239"
/db_xref="GeneID:855152"
CDS 511315..511569
/locus_tag="YMR122W-A"
/note="hypothetical protein; green fluorescent protein
(GFP)-fusion protein localizes to the cytoplasm and
endoplasmic reticulum"
/codon_start=1
/product="hypothetical protein"
/protein_id="NP_061493.1"
/db_xref="GI:9755340"
/db_xref="SGD:S000007524"
/db_xref="GeneID:855152"
/translation="MASSTSTSASASSSIKTNSALVSNNVVAASSVSATSTASSSAAK
NTTSSSKNAAPGMVANPVSSKYGIIMAAFAAVSFVLGTGI"
gene 513593..513961
/gene="PKR1"
/locus_tag="YMR123W"
/db_xref="GeneID:855153"
mRNA 513593..513961
/gene="PKR1"
/locus_tag="YMR123W"
/product="Pkr1p"
/transcript_id="NM_001182624.1"
/db_xref="GI:296147240"
/db_xref="GeneID:855153"
CDS 513593..513961
/gene="PKR1"
/locus_tag="YMR123W"
/note="V-ATPase assembly factor; functions with other
V-ATPase assembly factors in the ER to efficiently
assemble the V-ATPase membrane sector (V0); protein
abundance increases in response to DNA replication stress"
/codon_start=1
/product="Pkr1p"
/protein_id="NP_013842.1"
/db_xref="GI:6323771"
/db_xref="SGD:S000004730"
/db_xref="GeneID:855153"
/translation="MANFFVRLWESVFEPGTSPQLIIATHVSFVALLLTLIWLIYATN
GNIHFYALFCISLLLWITVIWFINELSHVKLKDNDELDKDANKKDDSAIKEDSEDKQE
SGKSTSTARRTQAQSRSRKA"
gene 514456..517287
/locus_tag="YMR124W"
/db_xref="GeneID:855154"
mRNA 514456..517287
/locus_tag="YMR124W"
/product="hypothetical protein"
/transcript_id="NM_001182625.1"
/db_xref="GI:296147241"
/db_xref="GeneID:855154"
CDS 514456..517287
/locus_tag="YMR124W"
/note="hypothetical protein; GFP-fusion protein localizes
to the cell periphery, cytoplasm, bud, and bud neck;
interacts with Crm1p in two-hybrid assay; YMR124W is not
an essential gene; predicted to have a role in organelle
organization"
/codon_start=1
/product="hypothetical protein"
/protein_id="NP_013843.1"
/db_xref="GI:6323772"
/db_xref="SGD:S000004731"
/db_xref="GeneID:855154"
/translation="MDAGLSTMATRNGQSSARVKLRNNLLNNDIGNIDIRDETPISRN
GNDSNINIQPSSVPQQQQQQQQYYRNGMNEAPIQAPLQQRQIPMQNYSQQQRQQQQYN
FEYSNPHMNEIPLMQHNFTKPSLSNNRDNVNGKKASSFTQSSFSNFFKHKHQFGKSKK
NTKGTGGGGDGDDDDEVILDDSANSDLTFNDIQTFGHKGGDKYGYGGDSTPIIPTLVT
KDRGNMSNTEYRKYITNQRKTAMNAMAKQTKNGTLASLPPRAMSLQSFPNGNPLMQAP
TPHPRFQPNKMVSANYSRSNSLMSGPPGQFRQPQQQRMLPMNNYNNHPGQFQNTPPVM
PSGQQPPQQPRTLSLTNGPRYSPQNPRPFAGHQQISQRQQQQQQQLQLHPMSEGYRTM
SLQSQNVPQGFNPWSPNDNDRKAVSMKQPISQSSISSKNNSAYSIPNVQNNSLTTFSP
SSPTDATAMPNSTKQGSSPLKKQVNIDQPIENKGKLNVLQLSTPQQNELKEKERKLAE
MEKSLREREALVEEKEKERAEKNTEANEEEEISHESDDLNLRPASALETGLKDLKLES
ESAVANRASLSTFSSTFSDSPSKQRIINTRTGMYKLENSTDINEYVTAQEFPSPGKYN
SNSDNGEMNTTNEVDFDFNTSKRASLLQSIPERDPKRNVSDATIKRRESDGNGRRLSN
VNISMNQENINNDTFLYKKNNRDGHLSAVSHMSSSSRRSFISNTLPLNIDSASESDNF
VPHMDGSPSKTKSAPVSYDKDGMNASEEDFSFDNTLAKPYEPLYARRGDITSAGSTSG
EDSSQPKMITISGEQLNLITENKELMNELTLVSTELAESIKRETELEERIRLYETNNS
APSFDDSSSVSFSDFEKELRKKSSKIVQLIQQLNDERLKRFIAEEQLLLQENGTKPSS
MELVGRIENLNKLIDERDSEIEMLKGRLQ"
gene 517539..520446
/gene="STO1"
/locus_tag="YMR125W"
/gene_synonym="CBC1; CBP80; GCR3; SUT1"
/db_xref="GeneID:855155"
mRNA join(517539..517563,517886..520446)
/gene="STO1"
/locus_tag="YMR125W"
/gene_synonym="CBC1; CBP80; GCR3; SUT1"
/product="Sto1p"
/transcript_id="NM_001182626.1"
/db_xref="GI:296147242"
/db_xref="GeneID:855155"
CDS join(517539..517563,517886..520446)
/gene="STO1"
/locus_tag="YMR125W"
/gene_synonym="CBC1; CBP80; GCR3; SUT1"
/note="Large subunit of the nuclear mRNA cap-binding
protein complex, interacts with Npl3p to carry nuclear
poly(A)+ mRNA to cytoplasm; also involved in nuclear mRNA
degradation and telomere maintenance; orthologous to
mammalian CBP80"
/codon_start=1
/product="Sto1p"
/protein_id="NP_013844.2"
/db_xref="GI:6579194"
/db_xref="SGD:S000004732"
/db_xref="GeneID:855155"
/translation="MFNRKRRGDFDEDENYRDFRPRMPKRQRIPPVVQLCKEMMPDIR
TIGESVKAFEDDIKFLSEAIMNEYGHEDYFNNALLSTLNAVVVEQPQKQAAIALLTMV
VNSKNNVAGKSIINYFFEELQKWCKQTYNDEFKSTSNETGPWNKIKLILRFLSILSPM
FLVDELINIYKSLFELSIELNNLDPGNRVPLSEAIYTNTLLNIPYLFFFNRNNDGLRT
KVEELLAYVEQNYLVKTTDINLLREYNGEPPYEMVELVRVVLPNVKKALINNLEQLNE
LFPDWNHLLTPQTGDEGFNDALTLPSVDDLKSFVRLNKNFGSVDSMWKTPRYAFHVYL
PNSAGNFETVVPISTYAGQLFNDIIIDLVESLEFNRKEVARQVITLDLFFKAGIFTEP
GESIAQLIATYEENPLAPTFKIEDLAIETILGLIFKLPSVSQPFAYFYTLLVDICQNS
PKAIAPVFGRAFRFFYSHLDSLDFELKLRYLDWFSIQMSNFNFSWKWNEWEDDSIKFG
KYFYNPKVNFAKNLIQKELRLTSNFSEVEDSLPQEFTKYLDTSYIPRDQLINYYQSLF
TGYTVEEDSVRKNDLYFRQEGVPMENTVRKILDYTHKANNSREVTELESILGELKNEY
GSIISDFNRFVIILLVQAVTDSGSRSLSHANKYINDLKEDLKTIFAKIELDIETKEYI
IIEAVLTFWNANPQTGFLVADAFKYAGLLTSRTIFTFIFNETGLKNNGLIEATAIEAV
FRNLSQQISEENESGNNFEFVFERLCTIANSTIDLLDVNADEDIEIPKVNGEMDIDDI
EDDKLDLKWKYFTVIGFIKSILRRYSHEYRELADKFIANIDNAIPHESTRRTISNWIQ
ETKEV"
gene complement(520761..521789)
/gene="DLT1"
/locus_tag="YMR126C"
/db_xref="GeneID:855156"
mRNA complement(520761..521789)
/gene="DLT1"
/locus_tag="YMR126C"
/product="Dlt1p"
/transcript_id="NM_001182627.1"
/db_xref="GI:296147243"
/db_xref="GeneID:855156"
CDS complement(520761..521789)
/gene="DLT1"
/locus_tag="YMR126C"
/note="hypothetical protein, mutant sensitive to
6-azauracil (6AU) and mycophenolic acid (MPA)"
/codon_start=1
/product="Dlt1p"
/protein_id="NP_013845.1"
/db_xref="GI:6323774"
/db_xref="SGD:S000004733"
/db_xref="GeneID:855156"
/translation="MSGFAKLKSWLYKASLFVSLILLIGFSVVLPIDSIAQASKSENN
AFNTFIVVGALVVFGVFCIFIIIGRMLFHKSCLKDIPRRYIPITPADLPHRSSREAVL
QNMERSKELTILLKKPKDPVIHDGLEPPRRCDYPLDEKLFPEYLNYADCIKSLTDRLK
YHGLFLNNLDVRMNLEDTFADVVNSQFVNHNANKIQLEKAKEFIDLYETIRFSGKDVT
RDQFIKFVKFCLYFGEVSLTRDTSFANLHNFRLNGSSNNIGRTESKYSINPFDENEYA
QDDMHYFPEPPTHLVRESSISTVARHVSSGVDLTNSEEHPLDTDSDCNALRLKLSKAD
SYRSVIRH"
gene complement(522329..523345)
/gene="SAS2"
/locus_tag="YMR127C"
/db_xref="GeneID:855157"
mRNA complement(522329..523345)
/gene="SAS2"
/locus_tag="YMR127C"
/product="Sas2p"
/transcript_id="NM_001182628.1"
/db_xref="GI:296147244"
/db_xref="GeneID:855157"
CDS complement(522329..523345)
/gene="SAS2"
/locus_tag="YMR127C"
/EC_number="2.3.1.48"
/note="Histone acetyltransferase (HAT) catalytic subunit
of the SAS complex (Sas2p-Sas4p-Sas5p), which acetylates
free histones and nucleosomes and regulates
transcriptional silencing; member of the
MYSTacetyltransferase family"
/codon_start=1
/product="Sas2p"
/protein_id="NP_013846.1"
/db_xref="GI:6323775"
/db_xref="SGD:S000004734"
/db_xref="GeneID:855157"
/translation="MARSLSQSLTATTQKLKGKKNGGKGKNKPSAKIKKTQKEMLYGI
LNERNIRQIQFGLNKKFSTWYGSAVYFDPETKRLGCSETKGQLSSVSNSQYWLDTLFV
CEYCFKYTDDQTRFVGHVASCPFQYRVPGKIKYKSPEYTIRRVKGSKYQLFCQCLCLF
TKLYLDNKSMYFKVDHYEFYIVYETGSTKPMGFFSKDLVSYQQNNLACILIFPPYQRR
GLGLLLIEFSYKLSQLEGVISGPEVPLSPFGLIGYLKYWSQILCWHLIEGDLAHYDKV
TLEDLSIVTGMRVNDVILTLKHLNCIGENNQIYLQSLNSWLKLHGTKRNWFKLKDEYL
LIDD"
gene 523696..527499
/gene="ECM16"
/locus_tag="YMR128W"
/gene_synonym="DHR1"
/db_xref="GeneID:855158"
mRNA 523696..527499
/gene="ECM16"
/locus_tag="YMR128W"
/gene_synonym="DHR1"
/product="Ecm16p"
/transcript_id="NM_001182629.1"
/db_xref="GI:296147245"
/db_xref="GeneID:855158"
CDS 523696..527499
/gene="ECM16"
/locus_tag="YMR128W"
/gene_synonym="DHR1"
/EC_number="3.6.1.-"
/note="Essential DEAH-box ATP-dependent RNA helicase
specific to the U3 snoRNP, predominantly nucleolar in
distribution, required for 18S rRNA synthesis"
/codon_start=1
/product="Ecm16p"
/protein_id="NP_013847.1"
/db_xref="GI:6323776"
/db_xref="SGD:S000004735"
/db_xref="GeneID:855158"
/translation="MGTYRKRFNEKARSGHMAKLKELKRIRNKQFTRQDENDERVENP
DSAPAESSTTEPNANAEILEPLTEEEKKMKKRKLQELFTPKESKVSRLKKKRLDKFIE
HQLKREERKTIIGKLQDYKIDTSLLTSSKRLGEGRQTKKEEFKEALSLERQGRGNEQT
NEILYEEYEPKVWDEYGEGGSSEDDDGEDDFEASFGSMPKPTDNEEKKSSGFIDHRPA
KFGGSGLSFGFSNIKVINKESKTPKKKYNWRQRVEMEELKKHGKEDEMDFDTTSEDDD
EEEDQEEEDKMHPSENPLEEVESADSETGSEKFDQNDVANEFKDWANQEIKKLEGRDQ
ELVTPTLNIDYKPIIRKEDLDDGLQEAYVPINENSTRKAFYVEVSRSDEIQKARIQLP
VFGEEHKIMEAIHHNDVVIICGETGSGKTTQVPQFLYEAGFGAEDSPDYPGMVGITQP
RRVAAVSMAERVANELGDHGHKVGYQIRFDSTAKEDTKVKFMTDGVLLREMMHDFKLT
KYSSIIIDEAHERNINTDILIGMLSRCVRLRAKLHKENPIEHKKLKLIIMSATLRVSD
FSENKTLFPIAPPVLQVDARQFPVSIHFNRRTAFNYTDEAFRKTCKIHQKLPPGAILV
FLTGQQEITHMVKRLRKEFPFKKNSKYNKDLETPVSKMGINSKTTDLEAEDIDFSVQV
IDQDKFKSAIRYEEDEGNSGNGEDEEDEEEEGFEEVLTEGQTANDPLYVLPLYSLLPT
KEQMRVFQKPPQGSRLCIVATNVAETSLTIPGVRYVVDSGRSKERKYNESNGVQSFEV
GWVSKASANQRSGRAGRTGPGHCYRLYSSAVFEHDFEQFSKPEILRMPVESIVLQMKS
MAIHNIINFPFPTPPDRVALSKAIQLLQYLGALDNKEMITEDGKKMSLFPLSPRFSKM
LLVSDEKACLPYIVAIVSALSVGDPFINEFELGINEISRKPNPDENLDDKIREHDEST
PGMDPELKKELRSKFYKSRSQFSKLDKFSDVFRLLSVVSAMDYVPKEQKEIFMKKNFL
RGKLMEEIVKLRKQLMYIIKSNTSKENIAVVIRNEDLKSDIPSVIQIKLLKQMICAGF
VDHVAVRADVLFPDDAKITNRTSIINIPYIPVLATRTPNIEDCFVYIHPTSILNNLGE
MPPKYMLYYSLHLGGNNKTRMNTLCDIASTPLANIARKGLLLTYSKPLTGQGLKTVNL
SPTERYCYVVPRFGSTVDNDLKIGWDLNPIAVHQKKQKGQWTVIKFITRKGFQTITGE
EKEKK"
gene 527804..531817
/gene="POM152"
/locus_tag="YMR129W"
/db_xref="GeneID:855159"
mRNA 527804..531817
/gene="POM152"
/locus_tag="YMR129W"
/product="Pom152p"
/transcript_id="NM_001182630.1"
/db_xref="GI:296147246"
/db_xref="GeneID:855159"
CDS 527804..531817
/gene="POM152"
/locus_tag="YMR129W"
/note="Glycoprotein subunit of the transmembrane ring of
the nuclear pore complex (NPC); contributes to
nucleocytoplasmic transport, NPC biogenesis and spindle
pole body duplication; homologous to human NUP210"
/codon_start=1
/product="Pom152p"
/protein_id="NP_013848.1"
/db_xref="GI:6323777"
/db_xref="SGD:S000004736"
/db_xref="GeneID:855159"
/translation="MEHRYNVFNDTPRGNHWMGSSVSGSPRPSYSSRPNVNTTRRFQY
SDDEPAEKIRPLRSRSFKSTESNISDEKSRISERDSKDRYINGDKKVDIYSLPLISTD
VLEISKQRTFAVILFLIIQCYKIYDLVILKSGLPLSGLLFKNYRFNFISKYFIIDSFF
LYVLPSFNIPRLTFKPWVVYLQILAMLLLNIFISSDHEFVLISLIMTTWRKLYTKELS
VTGSAINHHRIFDSSAHFKGALTIKILPENTAMFNPLHESYCLPMDTNLFKINSIDVP
IRINSTEEIEYIELEYRDLYTNSVELRSLSKKDFKIIDNPKSFLKKDQSVLKSHSNDF
EEGSTIRYLAVTLQDIGFYQIKKIVDSKKLNLKIHQSHLVVPYCPIASITGTGSNDRC
IGDSDNVSFEIQGVPPMKLAYSKIVNGQTFSYVDSSLQPEYFESPLQSSKSKQSFTQG
ELNDLKWGRNQPVNINLDSSITQDGKFAYKIDKITDGLGNVVDFTSLPEELKKRYDLS
YNFNVHEVPRAALEERFDPKSPTKRSIAIVFEEIKNWISDIPYVISLSYTDAQDKSKK
IMNVTTDSLTKVLQADLPGSYNLEYIESKFCPGEIVGKSNVLVTMPVAPTMEVKSFPI
LDQCVGQVGLNFELSFTGAPPYYYNTKIYKLENGERKLYDAKRYTSEGTRNRFSYSPP
KEGNYEIVFDTVSNKLFTEPIKLEPVKEYTFKTSMRVKPSASLKLHHDLKLCLGDHSS
VPVALKGQGPFTLTYDIIETFSSKRKTFEIKEIKTNEYVIKTPVFTTGGDYILSLVSI
KDSTGCVVGLSQPDAKIQVRRDIPSAAFNFFEPIKEAKIKHGSVTEIPLKLSGEGPFT
VKFKHMDYDGNIVKEFENKFQNSYKPALKVSKEGLYQLVDIRDSSCQGNVIYRNSLYK
VSFLEKPKFAIQDNHHITKVTENLFSKEEVCQGMEGTVDLALFGSPPFILEYDLMAPN
GHISTKKIQVATKYASLKLPNQIPGEYITTIKAIFDGNYGESDIHFREHQSELIIKQT
VHPIPDVAFADGGKTLRACAANVDQISFLEPINLKFLQGESPFSITFSVYHESTSRTD
QYTIDNIDSENFSFEKLYEGMKLGNHAITIDSVVDANGCVNSLISGPRNQILVSITDA
PKIHILDPSTEYCVGDYVAYQLNGVAPFMIKYEFNGIPLKSKERSSQFVRLASEPGII
SITSLQDSSSQCIVDFTNPKLKSEFDDLSLNIHPIPSVTVSQGNYVTEDIREGDQAEV
IFSFEGTPPFSLTYVRTEETDGKHGKRRSQVVETHKVTDIYSHEYKVITSLQGTYEAI
EITDAYCFAKNDLFFNN"
gene 532119..533027
/locus_tag="YMR130W"
/db_xref="GeneID:855160"
mRNA 532119..533027
/locus_tag="YMR130W"
/product="hypothetical protein"
/transcript_id="NM_001182631.1"
/db_xref="GI:296147247"
/db_xref="GeneID:855160"
CDS 532119..533027
/locus_tag="YMR130W"
/note="hypothetical protein; YMR130W is not an essential
gene"
/codon_start=1
/product="hypothetical protein"
/protein_id="NP_013849.1"
/db_xref="GI:6323778"
/db_xref="SGD:S000004737"
/db_xref="GeneID:855160"
/translation="MTYPKRIPINAWSEVHRVARPLIITFDAYNTLYATKLPVMEQYC
IVGRKYGIKANPSTLTNNFPHVFKKLKEDYPQYGKYSGIKPEQWWSILIRNVFAPNEI
PDEMINEILMRFEGFDSYFVYPDLIKFLKDLKSRHPDVILGIVSNTDPIFYKLLKNIG
LFETFSGHIYLSYELNLAKPDRAIFQYALDDIISKQPHLLEKYTREEILQHCFHIGDE
LKNDLEGAEAAGWTGILLDRNDKYGFLSNSISKPMRDEYKLSIDKIDNNSINTWEANT
KQTDTLQLSERKYVVSNLEVLEELFP"
gene complement(533163..534698)
/gene="RRB1"
/locus_tag="YMR131C"
/db_xref="GeneID:855161"
mRNA complement(533163..534698)
/gene="RRB1"
/locus_tag="YMR131C"
/product="Rrb1p"
/transcript_id="NM_001182632.1"
/db_xref="GI:296147248"
/db_xref="GeneID:855161"
CDS complement(533163..534698)
/gene="RRB1"
/locus_tag="YMR131C"
/note="Essential nuclear protein involved in early steps
of ribosome biogenesis; physically interacts with the
ribosomal protein Rpl3p"
/codon_start=1
/product="Rrb1p"
/protein_id="NP_013850.1"
/db_xref="GI:6323779"
/db_xref="SGD:S000004738"
/db_xref="GeneID:855161"
/translation="MSKRSIEVNEEQDRVVSAKTESHSVPAIPASEEQDAPKNDLEEQ
LSDEFDSDGEIIEIDGDDEINDEDDLRKKQEEAETLVQKDQSEGNKEKIQELYLPHMS
RPLGPDEVLEADPTVYEMLHNVNMPWPCLTLDVIPDTLGSERRNYPQSILLTTATQSS
RKKENELMVLALSNLAKTLLKDDNEGEDDEEDDEDDVDPVIENENIPLRDTTNRLKVS
PFAISNQEVLTATMSENGDVYIYNLAPQSKAFSTPGYQIPKSAKRPIHTVKNHGNVEG
YGLDWSPLIKTGALLSGDCSGQIYFTQRHTSRWVTDKQPFTVSNNKSIEDIQWSRTES
TVFATAGCDGYIRIWDTRSKKHKPAISVKASNTDVNVISWSDKIGYLLASGDDNGTWG
VWDLRQFTPSNADAVQPVAQYDFHKGAITSIAFNPLDESIVAVGSEDNTVTLWDLSVE
ADDEEIKQQAAETKELQEIPPQLLFVHWQKEVKDVKWHKQIPGCLVSTGTDGLNVWKT
ISV"
gene complement(534944..535570)
/gene="JLP2"
/locus_tag="YMR132C"
/db_xref="GeneID:855162"
mRNA complement(534944..535570)
/gene="JLP2"
/locus_tag="YMR132C"
/product="Jlp2p"
/transcript_id="NM_001182633.1"
/db_xref="GI:296147249"
/db_xref="GeneID:855162"
CDS complement(534944..535570)
/gene="JLP2"
/locus_tag="YMR132C"
/note="hypothetical protein, contains sequence that
closely resembles a J domain (typified by the E. coli DnaJ
protein)"
/codon_start=1
/product="Jlp2p"
/protein_id="NP_013851.1"
/db_xref="GI:6323780"
/db_xref="SGD:S000004739"
/db_xref="GeneID:855162"
/translation="MVYFYESKPTEYSTPYQIVMGKDKFENDLLIKWSYRELNYVWFH
ADKYSSGHVYLKLRPNEKTIDDIPQEVICDCLQLCKSESIQGNKMPQCTILITPWHNL
RKNRYMNPGEVSFKSLRQCRKMECGARDNKILNRLAKTRVELFNNVEATLNEAKKTKN
GDFFVNYIESNRSNLIEEEKLRKVAKKNQKKKNKQSKDEVTDDMQLEV"
rep_origin 535597..535844
/note="ARS1320;
Autonomously Replicating Sequence"
/db_xref="SGD:S000118373"
gene 536207..537609
/gene="REC114"
/locus_tag="YMR133W"
/db_xref="GeneID:855163"
mRNA join(536207..537448,537565..537609)
/gene="REC114"
/locus_tag="YMR133W"
/product="Rec114p"
/transcript_id="NM_001182634.1"
/db_xref="GI:296147250"
/db_xref="GeneID:855163"
CDS join(536207..537448,537565..537609)
/gene="REC114"
/locus_tag="YMR133W"
/note="Protein involved in early stages of meiotic
recombination; possibly involved in the coordination of
recombination and meiotic division; mutations lead to
premature initiation of the first meiotic division"
/codon_start=1
/product="Rec114p"
/protein_id="NP_013852.1"
/db_xref="GI:6323781"
/db_xref="SGD:S000004740"
/db_xref="GeneID:855163"
/translation="MYEYCSVVIKKYSKYTIPSFAPNGFQSMLEPPQIDKWQHLSANC
TLQFRVLLMDSRQILINVVLNNSTLLENIRLPLGDNQDLIQFSCKSPIISCKYISEEF
GPRMLRRFQMNLPNDVEFNRTVVSLKNLNFVLRTARTSIAQSTITSQVQGNNNGTKVC
FTEGPKVSSYTNPNTQFQTQNMIMDFSQRYQEESERESNNRSNITLPHDSIQIAQQIW
PNTDLNVVQSSQDLNTPMATQTVLGRPESLIVQPLEVSQSPPNTTNCLPNAENKKKKV
DTTSDFTSRKEIALCKTGLLETIHIPKERESQMQSVTGLDATPTIIWSPGKDNTAKKN
TSNKKNIDDKLTNPQKSGNTHTPDRNKEVLPNGTLNETRKEASPSEGLTIRVKNVNRN
ASRKISKRLIKEKLKDEEFMKWVNKVETVLNKMFEK"
gene 537838..538551
/locus_tag="YMR134W"
/db_xref="GeneID:855164"
mRNA 537838..538551
/locus_tag="YMR134W"
/product="hypothetical protein"
/transcript_id="NM_001182635.1"
/db_xref="GI:296147251"
/db_xref="GeneID:855164"
CDS 537838..538551
/locus_tag="YMR134W"
/note="hypothetical protein that may be involved in iron
metabolism; mutant bm-8 has a growth defect on
iron-limited medium that is complemented by overexpression
of Yfh1p; shows localization to the ER; highly conserved
in ascomycetes"
/codon_start=1
/product="hypothetical protein"
/protein_id="NP_013853.1"
/db_xref="GI:6323782"
/db_xref="SGD:S000004741"
/db_xref="GeneID:855164"
/translation="MSLKDRYLNLELKLINKLQELPYVHQFIHDRISGRITLFLIVVG
TLAFFNELYITIEMSLLQKNTSEELERGRIDESLKLHRMLVSDEYHGKEYKDEKSGIV
IEEFEDRDKFFAKPVFVSELDVECNVIVDGKELLSTPLKFHVEFSPEDYENEKRPEFG
TTLRVLRLRLYHYFKDCEIYRDIIKNEGGEGARKFTISNGVKIYNHKDELLPLNIDDV
QLCFLKIDTGNTIKCEFIL"
gene complement(538689..540056)
/gene="GID8"
/locus_tag="YMR135C"
/gene_synonym="DCR1"
/db_xref="GeneID:855166"
mRNA complement(538689..540056)
/gene="GID8"
/locus_tag="YMR135C"
/gene_synonym="DCR1"
/product="glucose-induced degradation complex subunit
GID8"
/transcript_id="NM_001182636.1"
/db_xref="GI:296147252"
/db_xref="GeneID:855166"
CDS complement(538689..540056)
/gene="GID8"
/locus_tag="YMR135C"
/gene_synonym="DCR1"
/note="Subunit of GID Complex, binds strongly to central
component Vid30p; GID Complex is involved in
proteasome-dependent catabolite inactivation of
fructose-1,6-bisphosphatase; recruits Rmd5p, Fyv10 and
Vid28p to GID Complex; contains LisH, CTLH, and CRA
domains that mediate binding to Vid30p (LisH) and Rmd5p
and Vid28p (CTLH and CRA); dosage-dependent regulator of
START"
/codon_start=1
/product="glucose-induced degradation complex subunit
GID8"
/protein_id="NP_013854.1"
/db_xref="GI:6323784"
/db_xref="SGD:S000004742"
/db_xref="GeneID:855166"
/translation="MTISTLSNETTKSGSCSGQGKNGGKDFTYGKKCFTKEEWKEQVA
KYSAMGELYANKTIHYPLKIQPNSSGGSQDEGFATIQTTPIEPTLPRLLLNYFVSMAY
EDSSIRMAKELGFIRNNKDIAVFNDLYKIKERFHIKHLIKLGRINEAMEEINSIFGLE
VLEETFNATGSYTGRTDRQQQQQQQQFDIDGDLHFKLLLLNLIEMIRSHHQQENITKD
SNDFILNLIQYSQNKLAIKASSSVKKMQELELAMTLLLFPLSDSADSGSIKLPKSLQN
LYSISLRSKIADLVNEKLLKFIHPRIQFEISNNNSKFPDLLNSDKKIITQNFTVYNNN
LVNGSNGTKITHISSDQPINEKMSSNEVTAAANSVWLNQRDGNVGTGSAATTFHNLEN
KNYWNQTSELLSSSNGKEKGLEFNNYYSSEFPYEPRLTQIMKLWCWCENQLHHNQIGV
PRVEN"
gene 541199..542881
/gene="GAT2"
/locus_tag="YMR136W"
/db_xref="GeneID:855167"
mRNA 541199..542881
/gene="GAT2"
/locus_tag="YMR136W"
/product="Gat2p"
/transcript_id="NM_001182638.1"
/db_xref="GI:296147253"
/db_xref="GeneID:855167"
CDS 541199..542881
/gene="GAT2"
/locus_tag="YMR136W"
/note="Protein containing GATA family zinc finger motifs;
similar to Gln3p and Dal80p; expression repressed by
leucine"
/codon_start=1
/product="Gat2p"
/protein_id="NP_013856.1"
/db_xref="GI:6323785"
/db_xref="SGD:S000004744"
/db_xref="GeneID:855167"
/translation="MQAPNIYPFSQTQPQALPGFTYGPPQLVFDHSAPRVDPLHSTVT
INSPLPLQHYNGPNAHINSANNNYAYYYHHPNNNDNNNHSNNTIKNNNINSVLPAVNI
QISNNSHYRNTHQIPSAPQRLVSIIPDPHMPPNISHFQLNNIHPQMHAPVATDIHFQQ
VPVYNKTNNGIGTDNINNDKPVNSNQNEVLDNIDERSCHEINRVVSFSKHFENNELTT
TANDLNIQSTMDELAKLKSLSNSTHFRQSIATQNFHSLQNHITTIENRLASLLTDRQQ
EQQQLKQQESEKESSSPFSNKIKLPSLQELTDSISTQHLPTFYDNKRHASDTDLKSST
LHGPLYHRHAFLSTSSSSPSPTAGSAPLQKLQVPRQDDPNDKKMNISSSPFNSITYIP
NTTLSPMVQTQLKNLTTSNLNTKKKNNRGRPRAIQRQPTLTTSSHFINNSNPGAAAVS
TTTPAANSDEKNPNAKKIIEFCFHCGETETPEWRKGPYGTRTLCNACGLFYRKVTKKF
GSKSSNLLLRYRRSIDLANDRRIPDFITIPNRFIHDMDNDQTLDSEYNTILQ"
rep_origin 542881..542978
/note="ARS1321;
Putative replication origin, identified in multiple array
studies, not yet confirmed by plasmid-based assay"
/db_xref="SGD:S000130190"
gene complement(542978..544963)
/gene="PSO2"
/locus_tag="YMR137C"
/gene_synonym="SNM1"
/db_xref="GeneID:855168"
mRNA complement(542978..544963)
/gene="PSO2"
/locus_tag="YMR137C"
/gene_synonym="SNM1"
/product="Pso2p"
/transcript_id="NM_001182639.1"
/db_xref="GI:296147254"
/db_xref="GeneID:855168"
CDS complement(542978..544963)
/gene="PSO2"
/locus_tag="YMR137C"
/gene_synonym="SNM1"
/EC_number="3.1.-.-"
/note="Nuclease required for DNA single- and double-strand
break repair; acts at a post-incision step in repair of
breaks that result from interstrand cross-links produced
by a variety of mono- and bi-functional psoralen
derivatives; induced by UV-irradiation; forms nuclear foci
upon DNA replication stress"
/codon_start=1
/product="Pso2p"
/protein_id="NP_013857.1"
/db_xref="GI:6323786"
/db_xref="SGD:S000004745"
/db_xref="GeneID:855168"
/translation="MSRKSIVQIRRSEVKRKRSSTASSTSEGKTLHKNTHTSSKRQRT
LTEFNIPTSSNLPVRSSSYSFSRFSCSTSNKNTEPVIINDDDHNSICLEDTAKVEITI
DTDEEELVSLHDNEVSAIENRTEDRIVTELEEQVNVKVSTEVIQCPICLENLSHLELY
ERETHCDTCIGSDPSNMGTPKKNIRSFISNPSSPAKTKRDIATSKKPTRVKLVLPSFK
IIKFNNGHEIVVDGFNYKASETISQYFLSHFHSDHYIGLKKSWNNPDENPIKKTLYCS
KITAILVNLKFKIPMDEIQILPMNKRFWITDTISVVTLDANHCPGAIIMLFQEFLANS
YDKPIRQILHTGDFRSNAKMIETIQKWLAETANETIDQVYLDTTYMTMGYNFPSQHSV
CETVADFTLRLIKHGKNKTFGDSQRNLFHFQRKKTLTTHRYRVLFLVGTYTIGKEKLA
IKICEFLKTKLFVMPNSVKFSMMLTVLQNNENQNDMWDESLLTSNLHESSVHLVPIRV
LKSQETIEAYLKSLKELETDYVKDIEDVVGFIPTGWSHNFGLKYQKKNDDDENEMSGN
TEYCLELMKNDRDNDDENGFEISSILRQYKKYNKFQVFNVPYSEHSSFNDLVKFGCKL
KCSEVIPTVNLNNLWKVRYMTNWFQCWENVRKTRAAK"
gene 545155..545730
/gene="CIN4"
/locus_tag="YMR138W"
/gene_synonym="GTP1; UGX1"
/db_xref="GeneID:855169"
mRNA 545155..545730
/gene="CIN4"
/locus_tag="YMR138W"
/gene_synonym="GTP1; UGX1"
/product="Cin4p"
/transcript_id="NM_001182640.1"
/db_xref="GI:296147255"
/db_xref="GeneID:855169"
CDS 545155..545730
/gene="CIN4"
/locus_tag="YMR138W"
/gene_synonym="GTP1; UGX1"
/note="GTP-binding protein involved in beta-tubulin
(Tub2p) folding; isolated as mutant with increased
chromosome loss and sensitivity to benomyl; regulated by
the GTPase-activating protein, Cin2p, the human retinitis
pigmentosa 2 (RP2) homolog"
/codon_start=1
/product="Cin4p"
/protein_id="NP_013858.1"
/db_xref="GI:6323787"
/db_xref="SGD:S000004746"
/db_xref="GeneID:855169"
/translation="MGLLSIIRKQKLRDKEIRCLILGLDNSGKSTIVNKLLPKDEQNN
DGIMPTVGFQIHSLMIKDVTISLWDIGGQRTLRPFWDNYFDKTQAMIWCIDVSLSMRF
DETLQELKELINRDENRIGYECAVIVVLNKIDLVEDKSELHRRCLLVESELKCLFKPD
IRIELVKCSGVTGEGIDNLRDRLVESCHFTQ"
gene 546125..547237
/gene="RIM11"
/locus_tag="YMR139W"
/gene_synonym="GSK3; MDS1"
/db_xref="GeneID:855170"
mRNA 546125..547237
/gene="RIM11"
/locus_tag="YMR139W"
/gene_synonym="GSK3; MDS1"
/product="Rim11p"
/transcript_id="NM_001182641.1"
/db_xref="GI:296147256"
/db_xref="GeneID:855170"
CDS 546125..547237
/gene="RIM11"
/locus_tag="YMR139W"
/gene_synonym="GSK3; MDS1"
/EC_number="2.7.11.1"
/note="Protein kinase; required for signal transduction
during entry into meiosis; promotes the formation of the
Ime1p-Ume6p complex by phosphorylating Ime1p and Ume6p;
shares similarity with mammalian glycogen synthase kinase
3-beta; protein abundance increases in response to DNA
replication stress"
/codon_start=1
/product="Rim11p"
/protein_id="NP_013859.1"
/db_xref="GI:6323788"
/db_xref="SGD:S000004747"
/db_xref="GeneID:855170"
/translation="MNIQSNNSPNLSNNIVSKQVYYAHPPPTIDPNDPVQISFPTTEV
VGHGSFGVVFATVIQETNEKVAIKKVLQDKRFKNRELEIMKMLSHINIIDLKYFFYER
DSQDEIYLNLILEYMPQSLYQRLRHFVHQRTPMSRLEIKYYMFQLFKSLNYLHHFANV
CHRDIKPQNLLVDPETWSLKLCDFGSAKQLKPTEPNVSYICSRYYRAPELIFGATNYT
NQIDIWSSGCVMAELLLGQPMFPGESGIDQLVEIIKILGTPSKQEICSMNPNYMEHKF
PQIKPIPLSRVFKKEDDQTVEFLADVLKYDPLERFNALQCLCSPYFDELKLDDGKINQ
ITTDLKLLEFDENVELGHLSPDELSSVKKKLYPKSK"
gene 547714..549183
/gene="SIP5"
/locus_tag="YMR140W"
/db_xref="GeneID:855171"
mRNA 547714..549183
/gene="SIP5"
/locus_tag="YMR140W"
/product="Sip5p"
/transcript_id="NM_001182642.1"
/db_xref="GI:296147257"
/db_xref="GeneID:855171"
CDS 547714..549183
/gene="SIP5"
/locus_tag="YMR140W"
/note="hypothetical protein; interacts with both the
Reg1p/Glc7p phosphatase and the Snf1p kinase; forms
cytoplasmic foci upon DNA replication stress"
/codon_start=1
/product="Sip5p"
/protein_id="NP_013860.1"
/db_xref="GI:6323789"
/db_xref="SGD:S000004748"
/db_xref="GeneID:855171"
/translation="MGNVPGKIDQEDSFNDVRPDSSYNTTSSNSVIKQYDEEASSRVR
TRRTTSLVNNILNGNNARTKTGSHLSSTSRRKTSREKELAKEAHAKQLVVRCSETVDG
GFLAPFGCYSFEKLDYDATVVKNLIIKRKLAPFYTPLQDFDESWTRDELIKIVDGLPL
HDTFDENLEEFEDVPIGNLRKSTFNELIDKSLSKKEQRRMHAKIFRARLYKKRILWQE
NENETFLERKLEMKRIGSKSSNVEDNTSSQPRKNYHLPSDDLKYTLYKNGSECPICFL
YFPGPFNYSKCCQQPICTECFVQIKRADPHFPHDEVDPTEPQTNDSEKDPNLLTSEPA
NCPYCATASFSITYQPPTNRETGIGGMPADSYVYKDAAISRADGGQPNISAITSDTIR
PDWEIKLNKERARLMRRSANATAIHISNRLIDPSHSRRRNTSHSITPIHDESTSASRS
PEPTINELEDQMVREAIRLSLEDQDNRKKSKNRNTSLRP"
gene complement(550206..551207)
/gene="RPL13B"
/locus_tag="YMR142C"
/db_xref="GeneID:855173"
mRNA complement(join(550206..550801,551204..551207))
/gene="RPL13B"
/locus_tag="YMR142C"
/product="ribosomal 60S subunit protein L13B"
/transcript_id="NM_001182644.1"
/db_xref="GI:296147258"
/db_xref="GeneID:855173"
CDS complement(join(550206..550801,551204..551207))
/gene="RPL13B"
/locus_tag="YMR142C"
/note="Ribosomal 60S subunit protein L13B; not essential
for viability; homologous to mammalian ribosomal protein
L13, no bacterial homolog; RPL13B has a paralog, RPL13A,
that arose from the whole genome duplication"
/codon_start=1
/product="ribosomal 60S subunit protein L13B"
/protein_id="NP_013862.1"
/db_xref="GI:6323791"
/db_xref="SGD:S000004750"
/db_xref="GeneID:855173"
/translation="MAISKNLPILKNHFRKHWQERVKVHFDQAGKKVSRRNARAARAA
KIAPRPLDLLRPVVRAPTVKYNRKVRAGRGFTLAEVKAAGLTAAYARTIGIAVDHRRQ
NRNQEIFDANVQRLKEYQSKIIVFPRDGKAPEAEQVLSAAATFPIAQPATDVEARAVQ
DNGESAFRTLRLARSEKKFRGIREKRAREKAEAEAEKKK"
gene 551928..552903
/gene="RPS16A"
/locus_tag="YMR143W"
/db_xref="GeneID:855174"
mRNA join(551928..551951,552496..552903)
/gene="RPS16A"
/locus_tag="YMR143W"
/product="ribosomal 40S subunit protein S16A"
/transcript_id="NM_001182645.1"
/db_xref="GI:296147259"
/db_xref="GeneID:855174"
CDS join(551928..551951,552496..552903)
/gene="RPS16A"
/locus_tag="YMR143W"
/note="Protein component of the small (40S) ribosomal
subunit; homologous to mammalian ribosomal protein S16 and
bacterial S9; RPS16A has a paralog, RPS16B, that arose
from the whole genome duplication"
/codon_start=1
/product="ribosomal 40S subunit protein S16A"
/protein_id="NP_013863.2"
/db_xref="GI:9755341"
/db_xref="SGD:S000004751"
/db_xref="GeneID:855174"
/translation="MSAVPSVQTFGKKKSATAVAHVKAGKGLIKVNGSPITLVEPEIL
RFKVYEPLLLVGLDKFSNIDIRVRVTGGGHVSQVYAIRQAIAKGLVAYHQKYVDEQSK
NELKKAFTSYDRTLLIADSRRPEPKKFGGKGARSRFQKSYR"
gene 553362..554390
/locus_tag="YMR144W"
/db_xref="GeneID:855175"
mRNA 553362..554390
/locus_tag="YMR144W"
/product="hypothetical protein"
/transcript_id="NM_001182646.1"
/db_xref="GI:296147260"
/db_xref="GeneID:855175"
CDS 553362..554390
/locus_tag="YMR144W"
/note="hypothetical protein; localized to the nucleus;
YMR144W is not an essential gene"
/codon_start=1
/product="hypothetical protein"
/protein_id="NP_013864.1"
/db_xref="GI:6323793"
/db_xref="SGD:S000004752"
/db_xref="GeneID:855175"
/translation="MEENKLSGNKPIQLATWSNQMGSPENNGNNANNGSDVQNVIQKA
LGLIRQLNNNGLMSPMEEEHSQPSSSQETLSVDREINEQGRLRLLMQAKDDNTRKEVG
TYSSPMDSAYARENMLNVLQSLVTHLNQAVSQIQQLKFKNMILTSNENNIQSRHEVED
NLQKQQFERMKCQFLLERQSLKDQLRKRENKIVKYKQKIIEKNKKLNNLAKVLNQHAI
SDTSQIDSFSSSVKKTPSSTTTPQEMKSDMLNTLGILATHVLKDEIDDDSGNQTILQL
AAGSISNDCNTTELEITCSPEMGRTITHNRPNTKDESIQDSHGNRTLQLPKMKSFSTI
DGSIKDIK"
rep_origin 553422..554331
/locus_tag="YMR144W"
/note="ARS1322;
Putative replication origin, identified in multiple array
studies, not yet confirmed by plasmid-based assay"
/db_xref="SGD:S000130191"
gene complement(554793..556475)
/gene="NDE1"
/locus_tag="YMR145C"
/gene_synonym="NDH1"
/db_xref="GeneID:855176"
mRNA complement(554793..556475)
/gene="NDE1"
/locus_tag="YMR145C"
/gene_synonym="NDH1"
/product="NADH-ubiquinone reductase (H(+)-translocating)
NDE1"
/transcript_id="NM_001182647.1"
/db_xref="GI:296147261"
/db_xref="GeneID:855176"
CDS complement(554793..556475)
/gene="NDE1"
/locus_tag="YMR145C"
/gene_synonym="NDH1"
/EC_number="1.6.5.3"
/note="Mitochondrial external NADH dehydrogenase, a type
II NAD(P)H:quinone oxidoreductase that catalyzes the
oxidation of cytosolic NADH; Nde1p and Nde2p provide
cytosolic NADH to the mitochondrial respiratory chain"
/codon_start=1
/product="NADH-ubiquinone reductase (H(+)-translocating)
NDE1"
/protein_id="NP_013865.1"
/db_xref="GI:6323794"
/db_xref="SGD:S000004753"
/db_xref="GeneID:855176"
/translation="MIRQSLMKTVWANSSRFSLQSKSGLVKYAKNRSFHAARNLLEDK
KVILQKVAPTTGVVAKQSFFKRTGKFTLKALLYSALAGTAYVSYSLYREANPSTQVPQ
SDTFPNGSKRKTLVILGSGWGSVSLLKNLDTTLYNVVVVSPRNYFLFTPLLPSTPVGT
IELKSIVEPVRTIARRSHGEVHYYEAEAYDVDPENKTIKVKSSAKNNDYDLDLKYDYL
VVGVGAQPNTFGTPGVYEYSSFLKEISDAQEIRLKIMSSIEKAASLSPKDPERARLLS
FVVVGGGPTGVEFAAELRDYVDQDLRKWMPELSKEIKVTLVEALPNILNMFDKYLVDY
AQDLFKEEKIDLRLKTMVKKVDATTITAKTGDGDIENIPYGVLVWATGNAPREVSKNL
MTKLEEQDSRRGLLIDNKLQLLGAKGSIFAIGDCTFHPGLFPTAQVAHQEGEYLAQYF
KKAYKIDQLNWKMTHAKDDSEVARLKNQIVKTQSQIEDFKYNHKGALAYIGSDKAIAD
LAVGEAKYRLAGSFTFLFWKSAYLAMCLSFRNRVLVAMDWAKVYFLGRDSSI"
gene complement(557481..558524)
/gene="TIF34"
/locus_tag="YMR146C"
/db_xref="GeneID:855177"
mRNA complement(557481..558524)
/gene="TIF34"
/locus_tag="YMR146C"
/product="Tif34p"
/transcript_id="NM_001182648.1"
/db_xref="GI:296147262"
/db_xref="GeneID:855177"
CDS complement(557481..558524)
/gene="TIF34"
/locus_tag="YMR146C"
/note="eIF3i subunit of the core complex of translation
initiation factor 3 (eIF3), which is essential for
translation; stimulates rate of ribosomal scanning during
translation reinitiation"
/codon_start=1
/product="Tif34p"
/protein_id="NP_013866.1"
/db_xref="GI:6323795"
/db_xref="SGD:S000004754"
/db_xref="GeneID:855177"
/translation="MKAIKLTGHERPLTQVKYNKEGDLLFSCSKDSSASVWYSLNGER
LGTLDGHTGTIWSIDVDCFTKYCVTGSADYSIKLWDVSNGQCVATWKSPVPVKRVEFS
PCGNYFLAILDNVMKNPGSINIYEIERDSATHELTKVSEEPIHKIITHEGLDAATVAG
WSTKGKYIIAGHKDGKISKYDVSNNYEYVDSIDLHEKSISDMQFSPDLTYFITSSRDT
NSFLVDVSTLQVLKKYETDCPLNTAVITPLKEFIILGGGQEAKDVTTTSANEGKFEAR
FYHKIFEEEIGRVQGHFGPLNTVAISPQGTSYASGGEDGFIRLHHFEKSYFDFKYDVE
KAAEAKEHMQEAN"
gene 559199..559870
/locus_tag="YMR147W"
/db_xref="GeneID:855178"
mRNA 559199..559870
/locus_tag="YMR147W"
/product="hypothetical protein"
/transcript_id="NM_001182649.1"
/db_xref="GI:296147263"
/db_xref="GeneID:855178"
CDS 559199..559870
/locus_tag="YMR147W"
/codon_start=1
/product="hypothetical protein"
/protein_id="NP_013867.1"
/db_xref="GI:6323796"
/db_xref="SGD:S000004755"
/db_xref="GeneID:855178"
/translation="MAARNRRKNNKKKSLLVTSAAQEKNATYVLVAEELHKKTIDLNM
GTETPLTENHENPIPAKEFKHQQKLEPIDEHDDGEDELSIKFKSMTKSSGPITEAEVQ
KLLLSYAFTSAAIQEDENEKESRHYPIKPPSPSASSLSAYFQSFVEKCKQVFYNFSLQ
TVEKLNALQNSLYEVFWIIFIYLNYWFPNVGDYVRYVCRSFSRHNEIAQLLTRIFTYN
INHLH"
gene 560366..560812
/gene="OSW5"
/locus_tag="YMR148W"
/db_xref="GeneID:855179"
mRNA 560366..560812
/gene="OSW5"
/locus_tag="YMR148W"
/product="Osw5p"
/transcript_id="NM_001182650.1"
/db_xref="GI:296147264"
/db_xref="GeneID:855179"
CDS 560366..560812
/gene="OSW5"
/locus_tag="YMR148W"
/note="hypothetical protein that may play a role in spore
wall assembly; predicted to contain an N-terminal
transmembrane domain; osw5 null mutant spores exhibit
increased spore wall permeability and sensitivity to
beta-glucanase digestion"
/codon_start=1
/product="Osw5p"
/protein_id="NP_013868.1"
/db_xref="GI:6323797"
/db_xref="SGD:S000004756"
/db_xref="GeneID:855179"
/translation="MVSTATFFFFVYLTLFVVIGFFSSLFIIPLLGISFVFAIGVVSF
GFCSNMSFKMAQLIYVRADAFLKKVLDKMALQTQPAQLQEPQEPLSTLRPVSNPTIPS
PLRQTARPSKFVTEEDVIFEPVSAQSAIARSLETTANKAGNKFQLS"
gene 560996..561856
/gene="SWP1"
/locus_tag="YMR149W"
/db_xref="GeneID:855180"
mRNA 560996..561856
/gene="SWP1"
/locus_tag="YMR149W"
/product="Swp1p"
/transcript_id="NM_001182651.1"
/db_xref="GI:296147265"
/db_xref="GeneID:855180"
CDS 560996..561856
/gene="SWP1"
/locus_tag="YMR149W"
/EC_number="2.4.99.18"
/note="Delta subunit of the oligosaccharyl transferase
glycoprotein complex, which is required for N-linked
glycosylation of proteins in the endoplasmic reticulum"
/codon_start=1
/product="Swp1p"
/protein_id="NP_013869.1"
/db_xref="GI:6323798"
/db_xref="SGD:S000004757"
/db_xref="GeneID:855180"
/translation="MQFFKTLAALVSCISFVLAYVAQDVHVSFPSTAGKSRVMIGKVE
PRIGIDETVPTTITVEDPNEVIQVNFAIESTNKPFQNTLLIGLPNKNLEMAFEPEIKD
NGKLSMYKYRIDLAKLDAALLQEASRSPEPIKATLILASSTAKPKENLFREILQLNLN
FDVDHSDSSLVDKFGIKPEIHHIFHAEPKRVAKPIAVIFVLIIFITILSLIVTWLNSC
AAAFNNIPTGVTAVYFLGFIATIVGFEVIFARYYLGTSIFETLFSSLYLGAPGLLTST
KFLRSFGQTI"
gene complement(561956..562528)
/gene="IMP1"
/locus_tag="YMR150C"
/db_xref="GeneID:855182"
mRNA complement(561956..562528)
/gene="IMP1"
/locus_tag="YMR150C"
/product="Imp1p"
/transcript_id="NM_001182652.1"
/db_xref="GI:296147266"
/db_xref="GeneID:855182"
CDS complement(561956..562528)
/gene="IMP1"
/locus_tag="YMR150C"
/EC_number="3.4.21.-"
/note="Catalytic subunit of the mitochondrial inner
membrane peptidase complex, required for maturation of
mitochondrial proteins of the intermembrane space; complex
contains Imp1p and Imp2p (both catalytic subunits), and
Som1p"
/codon_start=1
/product="Imp1p"
/protein_id="NP_013870.1"
/db_xref="GI:6323800"
/db_xref="SGD:S000004758"
/db_xref="GeneID:855182"
/translation="MTVGTLPIWSKTFSYAIRSLCFLHIIHMYAYEFTETRGESMLPT
LSATNDYVHVLKNFQNGRGIKMGDCIVALKPTDPNHRICKRVTGMPGDLVLVDPSTIV
NYVGDVLVDEERFGTYIKVPEGHVWVTGDNLSHSLDSRTYNALPMGLIMGKIVAANNF
DKPFWDGSIRNIWGFKWINNTFLDVQAKSN"
gene 563096..564193
/gene="YIM1"
/locus_tag="YMR152W"
/db_xref="GeneID:855183"
mRNA 563096..564193
/gene="YIM1"
/locus_tag="YMR152W"
/product="Yim1p"
/transcript_id="NM_001182654.1"
/db_xref="GI:296147267"
/db_xref="GeneID:855183"
CDS 563096..564193
/gene="YIM1"
/locus_tag="YMR152W"
/note="hypothetical protein; null mutant displays
sensitivity to DNA damaging agents; the authentic,
non-tagged protein is detected in highly purified
mitochondria in high-throughput studies; protein abundance
increases in response to DNA replication stress"
/codon_start=1
/product="Yim1p"
/protein_id="NP_013872.1"
/db_xref="GI:6323801"
/db_xref="SGD:S000004760"
/db_xref="GeneID:855183"
/translation="MSDEIVTNKSVTYVNNTTPVTITSSELDLRSCYQDDEVVIEVHA
AALNPIDFITHQLCNSYIFGKYPKTYSRDYSGVIIKAGKDVDNRWKVGDKVNGMYSHI
YGERGTLTHYLILNPAKDVPITHMVEVPKDENDPYDDFVYAAAWPLTFGTAFSTLYDF
KKDWTSDSKVLVIGASTSVSYAFVHIAKNYFNIGTVVGICSKNSIERNKKLGYDYLVP
YDEGSIVENVKKLKQSVLENDKFDMIFDSVGNHDFFPVIDQFLKPKAKNSFYVTIAGN
NKADYKNISWRDFVSLSSILKAINPFKKYNWRFGHPYPPNNFIEVGNEMIKKGTYKPP
IDSVYEFDQYKEAIDRLMSNRAKGKVVVKMK"
gene 564435..565862
/gene="NUP53"
/locus_tag="YMR153W"
/db_xref="GeneID:855184"
mRNA 564435..565862
/gene="NUP53"
/locus_tag="YMR153W"
/product="Nup53p"
/transcript_id="NM_001182656.1"
/db_xref="GI:296147268"
/db_xref="GeneID:855184"
CDS 564435..565862
/gene="NUP53"
/locus_tag="YMR153W"
/note="FG-nucleoporin component of central core of nuclear
pore complex (NPC); also part of the NPC nuclear basket;
contributes directly to nucleocytoplasmic transport;
involved in regulation of transcription and mitosis;
induces membrane tubulation, which may contribute to
nuclear pore assembly; NUP53 has a paralog, ASM4, that
arose from the whole genome duplication"
/codon_start=1
/product="Nup53p"
/protein_id="NP_013873.1"
/db_xref="GI:6323802"
/db_xref="SGD:S000004762"
/db_xref="GeneID:855184"
/translation="MADLQKQENSSRFTNVSVIAPESQGQHEQQKQQEQLEQQKQPTG
LLKGLNGFPSAPQPLFMEDPPSTVSGELNDNPAWFNNPRKRAIPNSIIKRSNGQSLSP
VRSDSADVPAFSNSNGFNNVTFGSKKDPRILKNVSPNDNNSANNNAHSSDLGTVVFDS
NEAPPKTSLADWQKEDGIFSSKTDNIEDPNLSSNITFDGKPTATPSPFRPLEKTSRIL
NFFDKNTKTTPNTASSEASAGSKEGASTNWDDHAIIIFGYPETIANSIILHFANFGEI
LEDFRVIKDFKKLNSKNMSKSPSLTAQKYPIYTGDGWVKLTYKSELSKSRALQENGII
MNGTLIGCVSYSPAALKQLASLKKSEEIINNKTSSQTSLSSKDLSNYRKTEGIFEKAK
AKAVTSKVRNAEFKVSKNSTSFKNPRRLEIKDGRSLFLRNRGKIHSGVLSSIESDLKK
REQASKSKKSWLNRLNNWLFGWNDL"
gene complement(565999..568182)
/gene="RIM13"
/locus_tag="YMR154C"
/gene_synonym="CPL1"
/db_xref="GeneID:855186"
mRNA complement(565999..568182)
/gene="RIM13"
/locus_tag="YMR154C"
/gene_synonym="CPL1"
/product="Rim13p"
/transcript_id="NM_001182657.1"
/db_xref="GI:296147269"
/db_xref="GeneID:855186"
CDS complement(565999..568182)
/gene="RIM13"
/locus_tag="YMR154C"
/gene_synonym="CPL1"
/EC_number="3.4.22.-"
/note="Calpain-like cysteine protease; involved in
proteolytic activation of Rim101p in response to alkaline
pH; localizes to punctate structures in alkaline
conditions and in vps4 mutant; has similarity to A.
nidulans palB"
/codon_start=1
/product="Rim13p"
/protein_id="NP_013875.1"
/db_xref="GI:6323804"
/db_xref="SGD:S000004763"
/db_xref="GeneID:855186"
/translation="MNDWHEFNAAIKSIYCNAEGDSSSIINRLVGLAMKSEDSTFIEA
VLVLKENVSKVDKQLRFLWLTSTINSRFYPPIPISEASPVSWNKTEYCAPGTEELQRR
YPGRAKLQNEEDYSGGIEQCRDVPDCSLVASLINLRSKNLNLPLIKQISSTKYHVNLS
FNGSNKRLVTVDISQIPTSVDGKQLSLKSNDISDKIGELALLLVSKGTYSTDGSNISI
DTYRLSGFLPEITQVNSYPFEKLWKFHKSNLCLMGAGTGNRSNDMIKPLVENHDYSII
DITYDSRLVKLRDPRNSALNVEISYEQYLKNFKQLYLNWNQEKLFKRSQVLHFRYDTS
RYNKFSIVADKPLFHLVNNSKVTETVWLLLESHLQDEGSQENRSVSFLNEAPECIICP
IEPPVECGGNHIGLQLVKLRLDAETERLLYCYSTTNNNFSIHSFSVVKEICFQRLKDT
KSLFAKVLFSFPYEIEGKASFDTCNFFQNPTFELEVHSEQDYQVLMDAACISTSSHDL
INIQVYYFNDYELIKPIMFDNHYQPGQGLKQDVPILTNVKYMIVCSTYGPPASTEFEL
LASIRLSSSWRLISGITLRSVNLIYGTYPYHCRNRFHWKETSDKLKIQMTLPTKKYST
NKLFIRVVPVESSARLRMRCNIFEPESALCVYECQEYRTCPSGGIVIPDLEVSRTNIV
VLMIERSVPISSCLPTEGQLDELELFVGSSQKIRIEKYSDDVIPK"
gene 568551..570194
/locus_tag="YMR155W"
/db_xref="GeneID:855187"
mRNA 568551..570194
/locus_tag="YMR155W"
/product="hypothetical protein"
/transcript_id="NM_001182658.1"
/db_xref="GI:296147270"
/db_xref="GeneID:855187"
CDS 568551..570194
/locus_tag="YMR155W"
/note="hypothetical protein; identified as interacting
with Hsp82p in a high-throughput two-hybrid screen"
/codon_start=1
/product="hypothetical protein"
/protein_id="NP_013876.1"
/db_xref="GI:6323805"
/db_xref="SGD:S000004764"
/db_xref="GeneID:855187"
/translation="MVKKHQNSKMGNTNHFGHLKSFVGGNVVALGAGTPYLFSFYAPQ
LLSKCHIPVSASSKLSFSLTIGSSLMGILAGIVVDRSPKLSCLIGSMCVFIAYLILNL
CYKHEWSSTFLISLSLVLIGYGSVSGFYASVKCANTNFPQHRGTAGAFPVSLYGLSGM
VFSYLCSKLFGENIEHVFIFLMVACGCMILVGYFSLDIFSNAEGDDASIKEWELQKSR
ETDDNIVPLYENSNDYIGSPVRSSSPATYETYALSDNFQETSEFFALEDRQLSNRPLL
SPSSPHTKYDFEDENTSKNTVGENSAQKSMRLHVFQSLKSSTFIGYYIVLGILQGVGL
MYIYSVGFMVQAQVSTPPLNQLPINAEKIQSLQVTLLSLLSFCGRLSSGPISDFLVKK
FKAQRLWNIVIASLLVFLASNKISHDFSSIEDPSLRASKSFKNISVCSAIFGYSFGVL
FGTFPSIVADRFGTNGYSTLWGVLTTGGVFSVSVFTDILGRDFKANTGDDDGNCKKGV
LCYSYTFMVTKYCAAFNLLFVLGIIGYTYYRRRATANSL"
gene complement(570300..571016)
/gene="TPP1"
/locus_tag="YMR156C"
/db_xref="GeneID:855188"
mRNA complement(570300..571016)
/gene="TPP1"
/locus_tag="YMR156C"
/product="Tpp1p"
/transcript_id="NM_001182659.1"
/db_xref="GI:296147271"
/db_xref="GeneID:855188"
CDS complement(570300..571016)
/gene="TPP1"
/locus_tag="YMR156C"
/EC_number="3.1.3.32"
/note="DNA 3'-phosphatase that functions in repair of
endogenous damage of double-stranded DNA, activity is
specific for removal of 3' phosphates at strand breaks;
has similarity to the l-2-haloacid dehalogenase
superfamily"
/codon_start=1
/product="Tpp1p"
/protein_id="NP_013877.1"
/db_xref="GI:6323806"
/db_xref="SGD:S000004765"
/db_xref="GeneID:855188"
/translation="MSHKLTILPFLIKFTPKFPQSIDHDEHGLNVYAFDLDHTIIKPK
SPNISFSRSASDWQFINFNSKKSTLDYLCNIIDNDPTAVIVIFSNQGGVITVPRTSKS
CTKYTNKILLFLKAIKNDERGETLSHRLWLYAAPKRPKTFAANHSKITFASLGESYNN
DPNIFEKVRKPMTGMVEFFKRDLESAYRVSEQISPIKLNWIYYCGDAAGRKKDFSDSD
IKFAENLHVEFKYPEEIFHG"
gene complement(571277..572044)
/gene="AIM36"
/locus_tag="YMR157C"
/gene_synonym="FMP39"
/db_xref="GeneID:855189"
mRNA complement(571277..572044)
/gene="AIM36"
/locus_tag="YMR157C"
/gene_synonym="FMP39"
/product="Aim36p"
/transcript_id="NM_001182660.1"
/db_xref="GI:296147272"
/db_xref="GeneID:855189"
CDS complement(571277..572044)
/gene="AIM36"
/locus_tag="YMR157C"
/gene_synonym="FMP39"
/note="hypothetical protein; null mutant displays reduced
respiratory growth and elevated frequency of mitochondrial
genome loss; the authentic, non-tagged protein is detected
in purified mitochondria in high-throughput studies"
/codon_start=1
/product="Aim36p"
/protein_id="NP_013878.1"
/db_xref="GI:6323807"
/db_xref="SGD:S000004766"
/db_xref="GeneID:855189"
/translation="MLRPLRKSVLASCRHCFKVCGGLPQKQLPLFSPLLLRARYSSTD
SSTKRSNKSDKIDAPGFKKIFLVAIIGTVIFVKTVQSLDKNKPKTTLSEEEFENVVKG
LKRRVAIFPQGEVDIKFSLSPSIEETRKVLQKSQGDDINELQFVDPVKVIDYYRTLRD
DRYEALLNEYYKKYGCDTYAYNLPTGMLVMLLGRYFKENFKTGDKLVVVNFPHSIADA
TRFENEVSIVSKIFVPRKLSGSDVCKYYETVGKADII"
gene 572248..572715
/gene="MRPS8"
/locus_tag="YMR158W"
/db_xref="GeneID:855190"
mRNA 572248..572715
/gene="MRPS8"
/locus_tag="YMR158W"
/product="mitochondrial 37S ribosomal protein MRPS8"
/transcript_id="NM_001182661.1"
/db_xref="GI:296147273"
/db_xref="GeneID:855190"
CDS 572248..572715
/gene="MRPS8"
/locus_tag="YMR158W"
/note="Mitochondrial ribosomal protein of the small
subunit"
/codon_start=1
/product="mitochondrial 37S ribosomal protein MRPS8"
/protein_id="NP_013879.1"
/db_xref="GI:6323808"
/db_xref="SGD:S000004767"
/db_xref="GeneID:855190"
/translation="MSLVKLANTCAHLQNCSKVRVALTSIPYTKLQLQFAYNLYQQGF
LSSLQKGSTMGPDKDFVEVTPDNISTRRLWVGLKYRDNKPVLSSCKLISKPNSRIHLP
MEDMKKLCSGVTIRNIKPLQPGELILVRAHNNIMDINEAISKKLDGEVLCRVK"
gene complement(572883..572955)
/gene="EMT4"
/locus_tag="tM(CAU)M"
/db_xref="GeneID:855191"
tRNA complement(572883..572955)
/gene="EMT4"
/locus_tag="tM(CAU)M"
/product="tRNA-Met"
/note="Methionine tRNA (tRNA-Met), functions in
translational elongation; not involved in translational
initiation; predicted by tRNAscan-SE analysis"
/db_xref="SGD:S000006664"
/db_xref="GeneID:855191"
LTR complement(573112..573338)
/note="Ty1 LTR"
/db_xref="SGD:S000007116"
gene complement(573194..573331)
/locus_tag="YMR158C-A"
/gene_synonym="YMR158C-B"
/db_xref="GeneID:855192"
mRNA complement(573194..573331)
/locus_tag="YMR158C-A"
/gene_synonym="YMR158C-B"
/product="hypothetical protein"
/transcript_id="NM_001184342.1"
/db_xref="GI:296147274"
/db_xref="GeneID:855192"
CDS complement(573194..573331)
/locus_tag="YMR158C-A"
/gene_synonym="YMR158C-B"
/note="hypothetical protein, may contain a lipid
attachment site; YMR158C-A is not an essential gene"
/codon_start=1
/product="hypothetical protein"
/protein_id="NP_013880.1"
/db_xref="GI:6323809"
/db_xref="SGD:S000007249"
/db_xref="GeneID:855192"
/translation="MKMNYHLSTSSYTTSMLSCTVLDDDIRYEKLSWKLDEAEMQGLI
M"
gene complement(574476..574928)
/gene="ATG16"
/locus_tag="YMR159C"
/gene_synonym="APG15; APG16; CVT11; SAP18"
/db_xref="GeneID:855194"
mRNA complement(574476..574928)
/gene="ATG16"
/locus_tag="YMR159C"
/gene_synonym="APG15; APG16; CVT11; SAP18"
/product="Atg16p"
/transcript_id="NM_001182663.1"
/db_xref="GI:296147275"
/db_xref="GeneID:855194"
CDS complement(574476..574928)
/gene="ATG16"
/locus_tag="YMR159C"
/gene_synonym="APG15; APG16; CVT11; SAP18"
/note="Conserved protein involved in autophagy; interacts
with Atg12p-Atg5p conjugates to form Atg12p-Atg5p-Atg16p
multimers, which localize to the pre-autophagosomal
structure and are required for autophagy; relocalizes from
nucleus to cytoplasmic foci upon DNA replication stress"
/codon_start=1
/product="Atg16p"
/protein_id="NP_013882.1"
/db_xref="GI:6323811"
/db_xref="SGD:S000004769"
/db_xref="GeneID:855194"
/translation="MGNFIITERKKAKEERSNPQTDSMDDLLIRRLTDRNDKEAHLNE
LFQDNSGAIGGNIVSHDDALLNTLAILQKELKSKEQEIRRLKEVIALKNKNTERLNDE
LISGTIENNVLQQKLSDLKKEHSQLVARWLKKTEKETEAMNSEIDGTK"
gene 575066..577516
/locus_tag="YMR160W"
/db_xref="GeneID:855195"
mRNA 575066..577516
/locus_tag="YMR160W"
/product="hypothetical protein"
/transcript_id="NM_001182664.1"
/db_xref="GI:296147276"
/db_xref="GeneID:855195"
CDS 575066..577516
/locus_tag="YMR160W"
/note="hypothetical protein; green fluorescent protein
(GFP)-fusion protein localizes to the membrane of the
vacuole; mutant has enhanced sensitivity to overexpression
of mutant huntingtin; YMR160W is not an essential gene;
relative distribution within the vacuolar membrane changes
upon DNA replication stress"
/codon_start=1
/product="hypothetical protein"
/protein_id="NP_013883.1"
/db_xref="GI:6323812"
/db_xref="SGD:S000004770"
/db_xref="GeneID:855195"
/translation="MDVVQQKQDKQLQHQTQEQQQIREDQQEVPPQRPRQQNRWKPWW
NSTADDEPNTGRIAEYPNGQGRSSPTTDFQDSVNSNNDNKGIWSKIASFATSRYRSAP
IVVDDNTRYSQLNTEQINFLENEAKDIISKKSKSWCWYEAIPHISNSSNIIDSIDTPG
IISVSGTGSAKCPLPLNKYPGEGGNPGYNVFINDSLILPSDNPLNFLHVQPLRTKVLN
TIKNYYNFPNEQHLYLRQKKTALLKDKRIIIISVVGDLPEKYEQRSLESQRSAYYLSR
KLSQNLAQEQPQRVLTLSFQCPLHNQDLIPTYKECVELLNHWAHLFKEVDSIFFVGVY
HSVPLTLLLAKYIVQNNEVLEFDENTTVSVLSFQSCLQGYRFWDHSTDFTSNSYNNLG
SNSSTNENDSNDHDSNNDFTTKSQQIKEKQLFQGIDKKQQDTLSKIKNYRRIDSSESK
LVQDALDWLLFNWDTFRLTFFGKLYDNFMTISEKLAIDYNHPKILRNLWCNGKYMGID
LKNANNLNLDTDDEATSNINDVHVRTPNFESRLKIPTNRLFEITLWDILMITENLGYK
QFIPIINLLSPFFISRSFNDYTLPPNIRKQYQNSNKIWLQEMDSKWKMNGHQLNYDQR
EGESLGSSSESLLPENISTVKDFLQFVQYQNEKSSDFVRIYSDIYDDDKVYKCFLYNT
IFTKNPLSRKHLRLNIDLDTPTSILNTVNQYDLVWKIHDSFSKLIQLKNLPQREIPHA
LRLSISLNCFLDSTTSTSGPVFQRDTVEALRRLTEIWRTYQDWSPPTRGLKHLRDILS
VLAMYDNPKNLINDVRRT"
gene 577718..578392
/gene="HLJ1"
/locus_tag="YMR161W"
/db_xref="GeneID:855196"
mRNA 577718..578392
/gene="HLJ1"
/locus_tag="YMR161W"
/product="Hlj1p"
/transcript_id="NM_001182665.1"
/db_xref="GI:296147277"
/db_xref="GeneID:855196"
CDS 577718..578392
/gene="HLJ1"
/locus_tag="YMR161W"
/note="Co-chaperone for Hsp40p, anchored in the ER
membrane; with its homolog Ydj1p promotes ER-associated
protein degradation (ERAD) of integral membrane
substrates; similar to E. coli DnaJ"
/codon_start=1
/product="Hlj1p"
/protein_id="NP_013884.1"
/db_xref="GI:6323813"
/db_xref="SGD:S000004771"
/db_xref="GeneID:855196"
/translation="MSFTEDQEKIALEILSKDKHEFYEILKVDRKATDSEIKKAYRKL
AIKLHPDKNSHPKAGEAFKVINRAFEVLSNEEKRSIYDRIGRDPDDRQMPSRGAASGF
RGSAGGSPMGGGFEDMFFNSRFGGQRAGPPEDIFDFLFNAGGSPFGASPFGPSASTFS
FGGPGGFRVYTNNRGGSPFMRQQPRSRQQQQQAEENAVNSQLKNMLVLFIIFIVLPMI
KDYLFS"
gene complement(578951..583921)
/gene="DNF3"
/locus_tag="YMR162C"
/db_xref="GeneID:855197"
mRNA complement(578951..583921)
/gene="DNF3"
/locus_tag="YMR162C"
/product="aminophospholipid-translocating P4-type ATPase
DNF3"
/transcript_id="NM_001182666.1"
/db_xref="GI:296147278"
/db_xref="GeneID:855197"
CDS complement(578951..583921)
/gene="DNF3"
/locus_tag="YMR162C"
/EC_number="3.6.3.1"
/note="Aminophospholipid translocase (flippase) that
maintains membrane lipid asymmetry in post-Golgi secretory
vesicles; localizes to the trans-Golgi network; likely
involved in protein transport; type 4 P-type ATPase"
/codon_start=1
/product="aminophospholipid-translocating P4-type ATPase
DNF3"
/protein_id="NP_013885.1"
/db_xref="GI:6323814"
/db_xref="SGD:S000004772"
/db_xref="GeneID:855197"
/translation="MGIADGQRRRSSSLRTQMFNKHLYDKYRGRTDDEIELEDINESK
TFSGSDNNDKDDRDETSGNYAAEEDYEMEEYGSPDVSYSIITKILDTILDRRRTFHSK
DGRHIPIILDHNAIEYKQAATKRDGHLIDERFNKPYCDNRITSSRYTFYSFLPRQLYA
QFSKLANTYFFIVAVLQMIPGWSTTGTYTTIIPLCVFMGISMTREAWDDFRRHRLDKE
ENNKPVGVLVKDGNNDAQEVYTLPSSVVSSTAYLTKSAAAENNPPLNDDRNSSQGHFL
DTHFNNFELLKNKYNVHIHQKKWEKLRVGDFVLLTQDDWVPADLLLLTCDGENSECFV
ETMALDGETNLKSKQPHPELNKLTKAASGLANINAQVTVEDPNIDLYNFEGNLELKNH
RNDTIMKYPLGPDNVIYRGSILRNTQNVVGMVIFSGEETKIRMNALKNPRTKAPKLQR
KINMIIVFMVFVVATISLFSYLGHVLHKKKYIDQNKAWYLFQADAGVAPTIMSFIIMY
NTVIPLSLYVTMEIIKVVQSKMMEWDIDMYHAETNTPCESRTATILEELGQVSYIFSD
KTGTLTDNKMIFRKFSLCGSSWLHNVDLGNSEDNFEDNRDNTNSLRLPPKAHNGSSID
VVSIGDQNVLDRLGFSDAPIEKGHRPSLDNFPKSRNSIEYKGNSSAIYTGRPSMRSLF
GKDNSHLSKQASVISPSETFSENIKSSFDLIQFIQRYPTALFSQKAKFFFLSLALCHS
CLPKKTHNESIGEDSIEYQSSSPDELALVTAARDLGYIVLNRNAQILTIKTFPDGFDG
EAKLENYEILNYIDFNSQRKRMSVLVRMPNQPNQVLLICKGADNVIMERLHDRELAAK
KMADICTSTKERKDAEAELVLQQRKSLERMVDEEAMARTSLRNSLSSVPRASLSLQAV
RKSLSMKNSRTRDPEKQIDSIDQFLETVKKSDQEIGSVVNKSRKSLHKQQIEKYGPRI
SIDGTHFPNNNVPIDTRKEGLQHDYDTEILEHIGSDELILNEEYVIERTLQAIDEFST
EGLRTLVYAYKWIDIGQYENWNKRYHQAKTSLTDRKIKVDEAGAEIEDGLNLLGVTAI
EDKLQDGVSEAIEKIRRAGIKMWMLTGDKRETAINIGYSCMLIKDYSTVVILTTTDEN
IISKMNAVSQEVDSGNIAHCVVVIDGATMAMFEGNPTYMSVFVELCTKTDSVICCRAS
PSQKALMVSNIRNTDPNLVTLAIGDGANDIAMIQSADIGVGIAGKEGLQASRVSDYSI
GQFRFLLKLLFVHGRYNYIRTSKFMLCTFYKEITFYFTQLIYQRYTMFSGSSLYEPWS
LSMFNTLFTSLPVLCIGMFEKDLKPMTLLTVPELYSYGRLSQGFNWLIFMEWVILATT
NSLIITFLNVVMWGMSSLSDNTMYPLGLINFTAIVALINVKSQFVEMHNRNWLAFTSV
VLSCGGWLVWCCALPILNNTDQIYDVAYGFYNHFGKDITFWCTSLVLALLPITLDIVY
KTFKVMIWPSDSDIFAELEQKSDIRKKLELGAYSEMRQGWTWDKDPSTFTRYTDKVLS
RPRTNSRASAKTHNSSIYSMSNGNVDHSSKKNFFGNSSKKSSERYEVLPSGKLIKRPS
LKTQSSKDSIGGNITTKLTKKLKLPSRNVEDEDVNQIIQARLKDLE"
gene complement(584271..586388)
/gene="INP2"
/locus_tag="YMR163C"
/db_xref="GeneID:855198"
mRNA complement(584271..586388)
/gene="INP2"
/locus_tag="YMR163C"
/product="Inp2p"
/transcript_id="NM_001182667.1"
/db_xref="GI:296147279"
/db_xref="GeneID:855198"
CDS complement(584271..586388)
/gene="INP2"
/locus_tag="YMR163C"
/note="Peroxisome-specific receptor important for
peroxisome inheritance; co-fractionates with peroxisome
membranes and co-localizes with peroxisomes in vivo;
physically interacts with the myosin V motor Myo2p; INP2
is not an essential gene"
/codon_start=1
/product="Inp2p"
/protein_id="NP_013886.1"
/db_xref="GI:6323815"
/db_xref="SGD:S000004773"
/db_xref="GeneID:855198"
/translation="MTTNSRPSALQAPGLQIFSMLKSSEEDGFMSSSLTLDSDNIIGV
TENNRQEFYSTWRKPSLLSSRSVLHEYSPTIVGSNDCTFSPITVGKTTKFFNWDDIIS
RIFMQQPFGVTHQFFEEFRYSIITSHFLNDMNHYRLSLHLDQSIMNFHKSSTLLKNVP
PKSVPFMATKYGKLAVAEDKKLYFRQNFNYLSMIITSYRVLTQLKKYCRKKNSPGLKR
VVILILVAVYLSIQQEYFRRHLICYKTLLKVRKVLESLQQVDVMIHKYHLRFKEIKNH
SFISRVSLISIADEHSSVIKELLVFSSDALFYKLKSIIPDIVIFSDTSELSKYCELYG
IDVPNLYYNNTTTVKDLDGKLYRLKLLKKFMLCCLLSLDMTGNENLSNVNMRNALNKI
FPDYMARVQLKKKYNPIGTFQNIVSLLRGLHSLLSTVLVSLNDHKQILYAFPEETSTN
TGCERANVCSFSKNDKLFQALNYLKMIENNLLAIDIRNGITENDRNIIEDKLEELITF
WKTSKICGNISRIQKVSPTNTINHGFHLDILKGRKSPRSSSVQGLSLERKVDFIDVAE
SVNDSFENDTELEEYEDYDCQEECSAGSRQNHRVDFIGKDSCRKPDFKQLSDNELRRK
LDERILKLAQENREGRERLRTAKSFELLRKAQASMSVKFGFQKPLRDDAFLESRPLSK
CKVSSEETIPFLYELKGLLGNDS"
gene complement(586636..586709)
/locus_tag="tV(AAC)M3"
/db_xref="GeneID:855199"
tRNA complement(586636..586709)
/locus_tag="tV(AAC)M3"
/product="tRNA-Val"
/note="Valine tRNA (tRNA-Val), predicted by tRNAscan-SE
analysis"
/db_xref="SGD:S000006765"
/db_xref="GeneID:855199"
gene complement(587274..589550)
/gene="MSS11"
/locus_tag="YMR164C"
/db_xref="GeneID:855200"
mRNA complement(587274..589550)
/gene="MSS11"
/locus_tag="YMR164C"
/product="Mss11p"
/transcript_id="NM_001182668.1"
/db_xref="GI:296147280"
/db_xref="GeneID:855200"
CDS complement(587274..589550)
/gene="MSS11"
/locus_tag="YMR164C"
/note="Transcription factor involved in regulation of
invasive growth and starch degradation; controls the
activation of MUC1 and STA2 in response to nutritional
signals"
/codon_start=1
/product="Mss11p"
/protein_id="NP_013887.1"
/db_xref="GI:6323816"
/db_xref="SGD:S000004774"
/db_xref="GeneID:855200"
/translation="MDNTTNINTNERSSNTDFSSAPNIKGLNSHTQLQFDADSRVFVS
DVMAKNSKQLLYAHIYNYLIKNNYWNSAAKFLSEADLPLSRINGSASGGKTSLNASLK
QGLMDIASKGDIVSEDGLLPSKMLMDANDTFLLEWWEIFQSLFNGDLESGYQQDHNPL
RERIIPILPANSKSNMPSHFSNLPPNVIPPTQNSFPVSEESFRPNGDGSNFNLNDPTN
RNVSERFLSRTSGVYDKQNSANFAPDTAINSDIAGQQYATINLHKHFNDLQSPAQPQQ
SSQQQIQQPQHQPQHQPQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQHQQQQQTPYPI
VNPQMVPHIPSENSHSTGLMPSVPPTNQQFNAQTQSSMFSDQQRFFQYQLHHQNQGQA
PSFQQSQSGRFDDMNAMKMFFQQQALQQNSLQQNLGNQNYQSNTRNNTAEETTPTNDN
NANGNSLLQEHIRARFNKMKTIPQQMKNQSTVANPVVSDITSQQQYMHMMMQRMAANQ
QLQNSAFPPDTNRIAPANNTMPLQPGNMGSPVIENPGMRQTNPSGQNPMINMQPLYQN
VSSAMHAFAPQQQFHLPQHYKTNTSVPQNDSTSVFPLPNNNNNNNNNNNNNNNNNSNN
SNNNNNNNNNNNNSNNTPTVSQPSSKCTSSSSTTPNITTTIQPKRKQRVGKTKTKESR
KVAAAQKVMKSKKLEQNGDSAATNFINVTPKDSGGKGTVKVQNSNSQQQLNGSFSMDT
ETFDIFNIGDFSPDLMDS"
gene complement(590040..592628)
/gene="PAH1"
/locus_tag="YMR165C"
/gene_synonym="SMP2"
/db_xref="GeneID:855201"
mRNA complement(590040..592628)
/gene="PAH1"
/locus_tag="YMR165C"
/gene_synonym="SMP2"
/product="phosphatidate phosphatase PAH1"
/transcript_id="NM_001182669.1"
/db_xref="GI:296147281"
/db_xref="GeneID:855201"
CDS complement(590040..592628)
/gene="PAH1"
/locus_tag="YMR165C"
/gene_synonym="SMP2"
/note="Mg2+-dependent phosphatidate (PA) phosphatase;
dephosphorylates PA to yield diacylglycerol; responsible
for de novo lipid synthesis and formation of lipid
droplets; phosphorylation by Pho80p-Pho85p decreases
catalytic activity and alters Pah1p localization and
abundance; phosphorylation by protein kinase A decreases
catalytic efficiency; dephosphorylation by Nem1p-Spo7p
anchors Pah1p to the membrane increasing substrate
catalysis; homologous to mammalian lipins 1 and 2"
/codon_start=1
/product="phosphatidate phosphatase PAH1"
/protein_id="NP_013888.1"
/db_xref="GI:6323817"
/db_xref="SGD:S000004775"
/db_xref="GeneID:855201"
/translation="MQYVGRALGSVSKTWSSINPATLSGAIDVIVVEHPDGRLSCSPF
HVRFGKFQILKPSQKKVQVFINEKLSNMPMKLSDSGEAYFVFEMGDQVTDVPDELLVS
PVMSATSSPPQSPETSILEGGTEGEGEGENENKKKEKKVLEEPDFLDINDTGDSGSKN
SETTGSLSPTESSTTTPPDSVEERKLVEQRTKNFQQKLNKKLTEIHIPSKLDNNGDLL
LDTEGYKPNKNMMHDTDIQLKQLLKDEFGNDSDISSFIKEDKNGNIKIVNPYEHLTDL
SPPGTPPTMATSGSVLGLDAMESGSTLNSLSSSPSGSDTEDETSFSKEQSSKSEKTSK
KGTAGSGETEKRYIRTIRLTNDQLKCLNLTYGENDLKFSVDHGKAIVTSKLFVWRWDV
PIVISDIDGTITKSDALGHVLAMIGKDWTHLGVAKLFSEISRNGYNILYLTARSAGQA
DSTRSYLRSIEQNGSKLPNGPVILSPDRTMAALRREVILKKPEVFKIACLNDIRSLYF
EDSDNEVDTEEKSTPFFAGFGNRITDALSYRTVGIPSSRIFTINTEGEVHMELLELAG
YRSSYIHINELVDHFFPPVSLDSVDLRTNTSMVPGSPPNRTLDNFDSEITSGRKTLFR
GNQEEKFTDVNFWRDPLVDIDNLSDISNDDSDNIDEDTDVSQQSNISRNRANSVKTAK
VTKAPQRNVSGSTNNNEVLAASSDVENASDLVSSHSSSGSTPNKSTMSKGDIGKQIYL
ELGSPLASPKLRYLDDMDDEDSNYNRTKSRRASSAAATSIDKEFKKLSVSKAGAPTRI
VSKINVSNDVHSLGNSDTESRREQSVNETGRNQLPHNSMDDKDLDSRVSDEFDDDEFD
EDEFED"
gene complement(593367..594473)
/locus_tag="YMR166C"
/db_xref="GeneID:855202"
mRNA complement(593367..594473)
/locus_tag="YMR166C"
/product="hypothetical protein"
/transcript_id="NM_001182670.1"
/db_xref="GI:296147282"
/db_xref="GeneID:855202"
CDS complement(593367..594473)
/locus_tag="YMR166C"
/note="Predicted transporter of the mitochondrial inner
membrane; has similarity to human mitochondrial ATP-Mg/Pi
carriers; YMR166C is not an essential gene"
/codon_start=1
/product="hypothetical protein"
/protein_id="NP_013889.1"
/db_xref="GI:6323818"
/db_xref="SGD:S000004776"
/db_xref="GeneID:855202"
/translation="MNSWNLSSSIPIIHTPHDHPPTSEGTPDQPNNNRKDDKLHKKRG
DSDEDLSPIWHCVVSGGIGGKIGDSAMHSLDTVKTRQQGAPNVKKYRNMISAYRTIWL
EEGVRRGLYGGYMAAMLGSFPSAAIFFGTYEYTKRTMIEDWQINDTITHLSAGFLGDF
ISSFVYVPSEVLKTRLQLQGRFNNPFFQSGYNYSNLRNAIKTVIKEEGFRSLFFGYKA
TLARDLPFSALQFAFYEKFRQLAFKIEQKDGRDGELSIPNEILTGACAGGLAGIITTP
MDVVKTRVQTQQPPSQSNKSYSVTHPHVTNGRPAALSNSISLSLRTVYQSEGVLGFFS
GVGPRFVWTSVQSSIMLLLYQMTLRGLSNAFPTD"
gene 594886..597195
/gene="MLH1"
/locus_tag="YMR167W"
/gene_synonym="PMS2"
/db_xref="GeneID:855203"
mRNA 594886..597195
/gene="MLH1"
/locus_tag="YMR167W"
/gene_synonym="PMS2"
/product="mismatch repair ATPase MLH1"
/transcript_id="NM_001182671.1"
/db_xref="GI:296147283"
/db_xref="GeneID:855203"
CDS 594886..597195
/gene="MLH1"
/locus_tag="YMR167W"
/gene_synonym="PMS2"
/note="Protein required for mismatch repair in mitosis and
meiosis as well as crossing over during meiosis; forms a
complex with Pms1p and Msh2p-Msh3p during mismatch repair;
human homolog is associated with hereditary non-polyposis
colon cancer"
/codon_start=1
/product="mismatch repair ATPase MLH1"
/protein_id="NP_013890.1"
/db_xref="GI:6323819"
/db_xref="SGD:S000004777"
/db_xref="GeneID:855203"
/translation="MSLRIKALDASVVNKIAAGEIIISPVNALKEMMENSIDANATMI
DILVKEGGIKVLQITDNGSGINKADLPILCERFTTSKLQKFEDLSQIQTYGFRGEALA
SISHVARVTVTTKVKEDRCAWRVSYAEGKMLESPKPVAGKDGTTILVEDLFFNIPSRL
RALRSHNDEYSKILDVVGRYAIHSKDIGFSCKKFGDSNYSLSVKPSYTVQDRIRTVFN
KSVASNLITFHISKVEDLNLESVDGKVCNLNFISKKSISPIFFINNRLVTCDLLRRAL
NSVYSNYLPKGNRPFIYLGIVIDPAAVDVNVHPTKREVRFLSQDEIIEKIANQLHAEL
SAIDTSRTFKASSISTNKPESLIPFNDTIESDRNRKSLRQAQVVENSYTTANSQLRKA
KRQENKLVRIDASQAKITSFLSSSQQFNFEGSSTKRQLSEPKVTNVSHSQEAEKLTLN
ESEQPRDANTINDNDLKDQPKKKQKLGDYKVPSIADDEKNALPISKDGYIRVPKERVN
VNLTSIKKLREKVDDSIHRELTDIFANLNYVGVVDEERRLAAIQHDLKLFLIDYGSVC
YELFYQIGLTDFANFGKINLQSTNVSDDIVLYNLLSEFDELNDDASKEKIISKIWDMS
SMLNEYYSIELVNDGLDNDLKSVKLKSLPLLLKGYIPSLVKLPFFIYRLGKEVDWEDE
QECLDGILREIALLYIPDMVPKVDTSDASLSEDEKAQFINRKEHISSLLEHVLFPCIK
RRFLAPRHILKDVVEIANLPDLYKVFERC"
gene complement(597332..599158)
/gene="CEP3"
/locus_tag="YMR168C"
/gene_synonym="CBF3; CSL1"
/db_xref="GeneID:855204"
mRNA complement(597332..599158)
/gene="CEP3"
/locus_tag="YMR168C"
/gene_synonym="CBF3; CSL1"
/product="Cep3p"
/transcript_id="NM_001182672.1"
/db_xref="GI:296147284"
/db_xref="GeneID:855204"
CDS complement(597332..599158)
/gene="CEP3"
/locus_tag="YMR168C"
/gene_synonym="CBF3; CSL1"
/note="Essential kinetochore protein, component of the
CBF3 complex that binds the CDEIII region of the
centromere; contains an N-terminal Zn2Cys6 type zinc
finger domain, a C-terminal acidic domain, and a putative
coiled coil dimerization domain"
/codon_start=1
/product="Cep3p"
/protein_id="NP_013891.1"
/db_xref="GI:6323820"
/db_xref="SGD:S000004778"
/db_xref="GeneID:855204"
/translation="MFNRTTQLKSKHPCSVCTRRKVKCDRMIPCGNCRKRGQDSECMK
STKLITASSSKEYLPDLLLFWQNYEYWITNIGLYKTKQRDLTRTPANLDTDTEECMFW
MNYLQKDQSFQLMNFAMENLGALYFGSIGDISELYLRVEQYWDRRADKNHSVDGKYWD
ALIWSVFTMCIYYMPVEKLAEIFSVYPLHEYLGSNKRLNWEDGMQLVMCQNFARCSLF
QLKQCDFMAHPDIRLVQAYLILATTTFPYDEPLLANSLLTQCIHTFKNFHVDDFRPLL
NDDPVESIAKVTLGRIFYRLCGCDYLQSGPRKPIALHTEVSSLLQHAAYLQDLPNVDV
YREENSTEVLYWKIISLDRDLDQYLNKSSKPPLKTLDAIRRELDIFQYKVDSLEEDFR
SNNSRFQKFIALFQISTVSWKLFKMYLIYYDTADSLLKVIHYSKVIISLIVNNFHAKS
EFFNRHPMVMQTITRVVSFISFYQIFVESAAVKQLLVDLTELTANLPTIFGSKLDKLV
YLTERLSKLKLLWDKVQLLDSGDSFYHPVFKILQNDIKIIELKNDEMFSLIKGLGSLV
PLNKLRQESLLEEEDENNTEPSDFRTIVEEFQSEYNISDILS"
gene complement(599352..600872)
/gene="ALD3"
/locus_tag="YMR169C"
/db_xref="GeneID:855205"
mRNA complement(599352..600872)
/gene="ALD3"
/locus_tag="YMR169C"
/product="aldehyde dehydrogenase (NAD(+)) ALD3"
/transcript_id="NM_001182673.1"
/db_xref="GI:296147285"
/db_xref="GeneID:855205"
CDS complement(599352..600872)
/gene="ALD3"
/locus_tag="YMR169C"
/EC_number="1.2.1.3"
/note="Cytoplasmic aldehyde dehydrogenase, involved in
beta-alanine synthesis; uses NAD+ as the preferred
coenzyme; very similar to Ald2p; expression is induced by
stress and repressed by glucose"
/codon_start=1
/product="aldehyde dehydrogenase (NAD(+)) ALD3"
/protein_id="NP_013892.1"
/db_xref="GI:6323821"
/db_xref="SGD:S000004779"
/db_xref="GeneID:855205"
/translation="MPTLYTDIEIPQLKISLKQPLGLFINNEFCPSSDGKTIETVNPA
TGEPITSFQAANEKDVDKAVKAARAAFDNVWSKTSSEQRGIYLSNLLKLIEEEQDTLA
ALETLDAGKPFHSNAKQDLAQIIELTRYYAGAVDKFNMGETIPLTFNKFAYTLKVPFG
VVAQIVPWNYPLAMACRKMQGALAAGNTVIIKPAENTSLSLLYFATLIKKAGFPPGVV
NVIPGYGSVVGKALGTHMDIDKISFTGSTKVGGSVLEASGQSNLKDITLECGGKSPAL
VFEDADLDKAIEWVANGIFFNSGQICTANSRVYVQSSIYDKFVEKFKETAKKEWDVAG
KFDPFDEKCIVGPVISSTQYDRIKSYIERGKKEEKLDMFQTSEFPIGGAKGYFIPPTI
FTDVPETSKLLRDEIFGPVVVVSKFTNYDDALKLANDTCYGLASAVFTKDVKKAHMFA
RDIKAGTVWINQTNQEEAKVPFGGFKMSGIGRESGDTGVDNYLQIKSVHVDLSLDK"
gene complement(601562..603082)
/gene="ALD2"
/locus_tag="YMR170C"
/db_xref="GeneID:855206"
mRNA complement(601562..603082)
/gene="ALD2"
/locus_tag="YMR170C"
/product="aldehyde dehydrogenase (NAD(+)) ALD2"
/transcript_id="NM_001182674.1"
/db_xref="GI:296147286"
/db_xref="GeneID:855206"
CDS complement(601562..603082)
/gene="ALD2"
/locus_tag="YMR170C"
/EC_number="1.2.1.3"
/note="Cytoplasmic aldehyde dehydrogenase, involved in
ethanol oxidation and beta-alanine biosynthesis; uses NAD+
as the preferred coenzyme; expression is stress induced
and glucose repressed; very similar to Ald3p"
/codon_start=1
/product="aldehyde dehydrogenase (NAD(+)) ALD2"
/protein_id="NP_013893.1"
/db_xref="GI:6323822"
/db_xref="SGD:S000004780"
/db_xref="GeneID:855206"
/translation="MPTLYTDIEIPQLKISLKQPLGLFINNEFCPSSDGKTIETVNPA
TGEPITSFQAANEKDVDKAVKAARAAFDNVWSKTSSEQRGIYLSNLLKLIEEEQDTLA
ALETLDAGKPYHSNAKGDLAQILQLTRYFAGSADKFDKGATIPLTFNKFAYTLKVPFG
VVAQIVPWNYPLAMACWKLQGALAAGNTVIIKPAENTSLSLLYFATLIKKAGFPPGVV
NIVPGYGSLVGQALASHMDIDKISFTGSTKVGGFVLEASGQSNLKDVTLECGGKSPAL
VFEDADLDKAIDWIAAGIFYNSGQNCTANSRVYVQSSIYDKFVEKFKETAKKEWDVAG
KFDPFDEKCIVGPVISSTQYDRIKSYIERGKREEKLDMFQTSEFPIGGAKGYFIPPTI
FTDVPQTSKLLQDEIFGPVVVVSKFTNYDDALKLANDTCYGLASAVFTKDVKKAHMFA
RDIKAGTVWINSSNDEDVTVPFGGFKMSGIGRELGQSGVDTYLQTKAVHINLSLDN"
gene complement(603868..605520)
/gene="EAR1"
/locus_tag="YMR171C"
/db_xref="GeneID:855207"
mRNA complement(603868..605520)
/gene="EAR1"
/locus_tag="YMR171C"
/product="Ear1p"
/transcript_id="NM_001182675.1"
/db_xref="GI:296147287"
/db_xref="GeneID:855207"
CDS complement(603868..605520)
/gene="EAR1"
/locus_tag="YMR171C"
/note="Specificity factor required for Rsp5p-dependent
ubiquitination and sorting of specific cargo proteins at
the multivesicular body; mRNA is targeted to the bud via
the mRNA transport system involving She2p"
/codon_start=1
/product="Ear1p"
/protein_id="NP_013894.1"
/db_xref="GI:6323823"
/db_xref="SGD:S000004781"
/db_xref="GeneID:855207"
/translation="MSFKFLIESLLLGSISGQIRCGRSSVIPRGDVSYGGDDTDELNM
DIMLFAFGTLIVVYIVICIVYFFTKQIATRLITAYYNEHGPGQRISLFSDYDENNAHV
HSRRLMENMSLRWPNNLDDADEVRDKLAQLSPEEQFYYKQGEEYIKQNPPFLLNQGLL
QQSEDSNPDTTREDPIMNEQTRQYIQEEGAYAWEFSPNPDMPNHTVIVENKTEVSFLN
YNYDASISTNLPIPCINKVYYCEFKIFETDGPLNSDENVSKGVISFGLSTQPYPYFRL
PGRHHHSIAYDSNGARRFNDSFKLNEQLRTLFPQCEKGDIVGIGYRSRSGTVFFTRNG
KKLNEKSVGGHIRGWKFQYLYPIIGSNVPCQIHVNFGTYGFVYIEANVKKWGYAKSNG
IKLPPPSYEDYGKDTLLESGGEDNDFDEDFSDGDSDNIAAGSTTNLNDDIIIRNGEIL
PPPPGFEFTMSPPTGKKIINEEINLDSLPMLPPSYSDDEHHSKNDKSAISGRIIGTSR
NLITDEASFDSVDNDNEDENDHERDPEQFSEFDDYESRMHGI"
gene 605981..608140
/gene="HOT1"
/locus_tag="YMR172W"
/db_xref="GeneID:855208"
mRNA 605981..608140
/gene="HOT1"
/locus_tag="YMR172W"
/product="Hot1p"
/transcript_id="NM_001182677.1"
/db_xref="GI:296147288"
/db_xref="GeneID:855208"
CDS 605981..608140
/gene="HOT1"
/locus_tag="YMR172W"
/note="Transcription factor required for the transient
induction of glycerol biosynthetic genes GPD1 and GPP2 in
response to high osmolarity; targets Hog1p to osmostress
responsive promoters; has similarity to Msn1p and Gcr1p"
/codon_start=1
/product="Hot1p"
/protein_id="NP_013895.1"
/db_xref="GI:6323824"
/db_xref="SGD:S000004783"
/db_xref="GeneID:855208"
/translation="MSGMGIAILCIVRTKIYRITISFDYSTLMSPFFLFLMMPTTLKD
GYRMNSQVNEDAIGINLDLSLPTHISPTTGSESASGSNASTLRNDGNALDGGLLRTSA
AISAPTGTSQPTETIGEKLSNEERVNSNVSASNSTTAGTGRMLSQSLTNDSPSNEIST
DQLKIFQRMDEMSARMIEMEESFNKLSNKIAEQNTMVLNLKQDNYKVMNKLNILLKLV
AQPSARPSTNNAQNKLAIELLNSISAVSSAYLQKMQNNGSGRQHTADLCTGDSNTHSG
INQHRTTNGTIDVNTNTAQLNNQFSNALNTILPDQQHNRNNVSQNINQSLPNRQLGPV
INTQANQNQSQVLIHNTNTHQQVNRSPISFPNASTDKPFKLNPNGIKRRRRNTQSNNN
ASTNDHASAAQKPISALSPLTNSHNSTTSMNYTNSSIHSGVTSASNSFHDLNSLNNFG
TTTALSLPSLALDNASFPPNQNVIPPIINNTQQPLSFSQLINQDSTTSELLPSGKSGV
NTNIVNRNRASTLPSYPKPMTVKSNVDDDGYQEDDDDDGDDEGDGRDNEEDSTAEEDE
VDDEIETDMKNASINKRRRSLHHKKSNSLNGRRKLHGESATKPNINSDLHYRILKAPT
DVKTIWEEYDTGIRGKPSIKHLEAKYGNKWRLNKNKKTFSRRKRLYKFILNGMERGKT
AQEMIETLENKRLYKDDEDGEVKKRTIGWLQESLAGI"
gene 608689..609981
/gene="DDR48"
/locus_tag="YMR173W"
/db_xref="GeneID:855210"
mRNA 608689..609981
/gene="DDR48"
/locus_tag="YMR173W"
/product="DNA damage-responsive protein 48"
/transcript_id="NM_001182678.1"
/db_xref="GI:296147289"
/db_xref="GeneID:855210"
CDS 608689..609981
/gene="DDR48"
/locus_tag="YMR173W"
/note="DNA damage-responsive protein; expression is
increased in response to heat-shock stress or treatments
that produce DNA lesions; contains multiple repeats of the
amino acid sequence NNNDSYGS; protein abundance increases
in response to DNA replication stress"
/codon_start=1
/product="DNA damage-responsive protein 48"
/protein_id="NP_013897.1"
/db_xref="GI:6323826"
/db_xref="SGD:S000004784"
/db_xref="GeneID:855210"
/translation="MGLFDKVKQFANSNNNNNDSGNNNQGDYVTKAENMIGEDRVNQF
KSKIGEDRFDKMESKVRQQFSNTSINDNDSNNNDSYGSNNNDSYGSNNNDSYGSNNND
SYGSNNNDSYGSNNDDSYGSSNKKKSSYGSNNDDSYGSSNNNDSYGSNNNDSYGSNNN
DSYGSNNDDSYGSSNKNKSSYGSNNDDSYGSNNDDSYGSSNKKKSSYGSSNNDSYGSN
NDDSYGSNNNDSYGSNNDDSYGSSNKKKSSYGSNNDDSYGSSNNNDSYGSNNDDSYGS
SNKNKSSYGSSSNDDSYGSSNNDDSYGSSNKKKSSYGSNNDDSYGSNNDDSYGSSNKK
KSSYGSSNNDSYGSNNDDSYGSSNKKKSSYGSNNDDSYGSSNNNDSYGSNNDDSYGSS
NRNKNSYGSSNYGSSNNDDSYGSSNRGGRNQYGGDDDY"
gene complement(610159..610365)
/gene="PAI3"
/locus_tag="YMR174C"
/db_xref="GeneID:855212"
mRNA complement(610159..610365)
/gene="PAI3"
/locus_tag="YMR174C"
/product="Pai3p"
/transcript_id="NM_001182680.1"
/db_xref="GI:296147290"
/db_xref="GeneID:855212"
CDS complement(610159..610365)
/gene="PAI3"
/locus_tag="YMR174C"
/note="Cytoplasmic proteinase A (Pep4p) inhibitor,
dependent on Pbs2p and Hog1p protein kinases for osmotic
induction; intrinsically unstructured, N-terminal half
becomes ordered in the active site of proteinase A upon
contact"
/codon_start=1
/product="Pai3p"
/protein_id="NP_013899.1"
/db_xref="GI:6323828"
/db_xref="SGD:S000004786"
/db_xref="GeneID:855212"
/translation="MNTDQQKVSEIFQSSKEKLQGDAKVVSDAFKKMASQDKDGKTTD
ADESEKHNYQEQYNKLKGAGHKKE"
gene 611016..611255
/gene="SIP18"
/locus_tag="YMR175W"
/db_xref="GeneID:855213"
mRNA 611016..611255
/gene="SIP18"
/locus_tag="YMR175W"
/product="Sip18p"
/transcript_id="NM_001182681.1"
/db_xref="GI:296147291"
/db_xref="GeneID:855213"
CDS 611016..611255
/gene="SIP18"
/locus_tag="YMR175W"
/note="Phospholipid-binding hydrophilin; essential to
overcome desiccation-rehydration process; expression is
induced by osmotic stress"
/codon_start=1
/product="Sip18p"
/protein_id="NP_013900.1"
/db_xref="GI:6323829"
/db_xref="SGD:S000004787"
/db_xref="GeneID:855213"
/translation="MSNMMNKFAEKLQGNDDSHQKGKNAKSSNKERDDMNMDMGMGHD
QSEGGMKMGHDQSGTKMNAGRGIANDWKTYENMKK"
rep_origin 611275..611489
/note="ARS1323;
Autonomously Replicating Sequence"
/db_xref="SGD:S000118374"
gene 611314..611508
/locus_tag="YMR175W-A"
/db_xref="GeneID:1466501"
mRNA 611314..611508
/locus_tag="YMR175W-A"
/product="hypothetical protein"
/transcript_id="NM_001184660.1"
/db_xref="GI:296147292"
/db_xref="GeneID:1466501"
CDS 611314..611508
/locus_tag="YMR175W-A"
/codon_start=1
/product="hypothetical protein"
/protein_id="NP_878143.1"
/db_xref="GI:33438855"
/db_xref="SGD:S000028848"
/db_xref="GeneID:1466501"
/translation="MNCLCLCSLYSKSISAYFSEFSSTNIYKSYLRLPSVLYYVCMMH
TMMPNQLDAVGIQSSESLLM"
gene 611740..615975
/gene="ECM5"
/locus_tag="YMR176W"
/db_xref="GeneID:855214"
mRNA 611740..615975
/gene="ECM5"
/locus_tag="YMR176W"
/product="Ecm5p"
/transcript_id="NM_001182682.1"
/db_xref="GI:296147293"
/db_xref="GeneID:855214"
CDS 611740..615975
/gene="ECM5"
/locus_tag="YMR176W"
/note="Non-essential hypothetical protein; contains
ATP/GTP-binding site motif A; null mutant exhibits
cellular volume up to four times greater than wild-type,
also large drooping buds with elongated necks; relative
distribution to the nucleus increases upon DNA replication
stress"
/codon_start=1
/product="Ecm5p"
/protein_id="NP_013901.1"
/db_xref="GI:6323830"
/db_xref="SGD:S000004788"
/db_xref="GeneID:855214"
/translation="MSGHDSVTKISHILNEPVNEKVMVQNGFHESSKIADIELEIQER
PSIKQWESPRSAVIPTSNHNFSPFLYTQFKSRGAAPFAPETIKSVDLVELPEGVPARV
FHEKTGLFYQISPHSIPTFILAKKELPDPIKFYELVEDLGSVYGCVKLKIIPDADKFT
QLNVDVDRLWFKARKQFFNSNEFQRTKIVDFYAKLYNFHNKIKKSTLTRIPSIDKRTL
DLYRLRSCVKLRGGFNAVCEKKLWAQIGRELGYSGRIMSSLSTSLRSAYAKILLDFDI
YEEEEQAARNNEKNEDMVESEIFRHSNSRSRDEEEPLHKKAKIHRDVFRAGSINHEFK
RMRDIKHIKGFPTYFNSLTEFKLGYTQSTETTLPGYDFTFWENGMEIYDKSKYETKTS
PVYNLRQYYEKSLAVFTAIVAKFGSSYPDLFAKHTTLPQKEFERLYFHLLSEHFIDFE
IDTGLGLPCSMRSPGNNSSNEKFAIKNILDQWNLDNIPLNELSLLQHLDLDMANFTRT
TYDIGMLFSCQGWSVSDHFLPSIDFNHLGSTKLVYSIAPKDMEKFEALIARGKSEWDT
IQSRPRYSTSDDELKSFIETDFYKSFLDAEQSADYSNTGDNSKNSFPEDKIAGNTLHD
GSQSDFIFEPNFILANGIKLYKTTQEQGSYIFKFPKAFTCSIGSGFYLSQNAKFAPSS
WLRFSSEAAKWTSKMGFLPGLDVNQLLINALLNSNNPVLRKKCRDLISNYVVEEAENS
KKLGELIGTVDVVYNKLNYISDISLESTGLSKIVVTHGALQRNLSLKEFVVLLEKPEN
GAHSICGIPIRDQSGNLNVCLHSYFDSASLGIALDGLDKPPTSYLLVHNEDFEKKWDV
LMTSTFRNRTVPLNIIQYLISHTDSNTEFNRMLRSNFDDSLLLIEKCKKFIKTFVDVS
CSVKDVDFGNGFNLRHLPLKFSDNMADNLESLYESVRKCSIEFSEKPTIIRLYHVSRQ
FPIDNRDIIDGNNLDLLKELYQKSLTIPLKVSYWTKLTRKICRLEWLSVYEHIFIERC
DIKNEDPAKYSLPLLYSYFEFGLKYCDSEDIDKLGEVRKLILKYQDMMQKVRVFLKKD
PPSKISLSDLEDVLLDIEEYRLPIQSSFFSELDYVIREIENAKKMNDVNILYNTDNID
KIDELIRKNDPKFVKFANQFNGSRLDKRPLASDNSGSVKAKQELKVFKLWNQHLDQIM
QKNKFIEILPSIFRCLDLKSDKYIPLESCSKRQTKYCFCRRVEEGTAMVECEICKEWY
HVDCISNGELVPPDDPNVLFVCSICTPPCMAVDNIEGVTFELDDLKRILVESLKLSLI
PDPPILKNLFDVFAFALNFKNEMEKELFTNGYVNQLSSTHKIKYYLRKLKGSQCGFTN
LTDPLRKHCQVKDAEAIKWLTDNGRIIITGIPN"
gene 616566..618098
/gene="MMT1"
/locus_tag="YMR177W"
/db_xref="GeneID:855215"
mRNA 616566..618098
/gene="MMT1"
/locus_tag="YMR177W"
/product="Mmt1p"
/transcript_id="NM_001182683.1"
/db_xref="GI:296147294"
/db_xref="GeneID:855215"
CDS 616566..618098
/gene="MMT1"
/locus_tag="YMR177W"
/note="Putative metal transporter involved in
mitochondrial iron accumulation; closely related to Mmt2p"
/codon_start=1
/product="Mmt1p"
/protein_id="NP_013902.1"
/db_xref="GI:6323831"
/db_xref="SGD:S000004789"
/db_xref="GeneID:855215"
/translation="MLRICVKRPCIKIVLSQVRPALLVRKENLHISTGVKVEKSSIIN
QKDPNKVRVEINELKRQAEIEKAAIKELEKNPQYQKLAEAFNSHDHVHLRESETEQND
IISLGTIRDYKSSKCEQADKPSSLNLHSHTHSHGHTHSHAAHNPLLVLSTEQIRKNAG
VRITWVGLGVNVGIAIGKFFGGIVFHSQALFADAIHAISDMVSDLLTLLSVGLAANKP
TADYPYGYGKIETVGSLAVSTILAMAGISIGWSSLCALVGPVIPHTIIDTIGNLGHAH
TYSEDIIEDVTDINAAWIAAASIAAKEWIFRATRKIAINTNSNVLMANAWHHRVDSLT
SLVALVAISTGYLVNIQSLDTIGGLIVSGLIIKAGGEGMCIAIKELIDQSVSRDDPRY
LEIETLVKDTLNKLISNNNSQKPYGLKELTLLSSGPNLRGHLTLEVPLQKWGNILGVN
EFEIVTHHLRNVLTNEVSNLRRLDIEYVEEKNGEENEHIKGQQNYKEDVLIKHDHTNT
HI"
gene 618479..619303
/locus_tag="YMR178W"
/db_xref="GeneID:855216"
mRNA 618479..619303
/locus_tag="YMR178W"
/product="hypothetical protein"
/transcript_id="NM_001182684.1"
/db_xref="GI:296147295"
/db_xref="GeneID:855216"
CDS 618479..619303
/locus_tag="YMR178W"
/note="hypothetical protein; green fluorescent protein
(GFP)-fusion protein localizes to both the cytoplasm and
nucleus; YMR178W is not an essential gene; protein
abundance increases in response to DNA replication stress"
/codon_start=1
/product="hypothetical protein"
/protein_id="NP_013903.1"
/db_xref="GI:6323832"
/db_xref="SGD:S000004790"
/db_xref="GeneID:855216"
/translation="MVKVTAACIIIGDEVLNGKVVDTNSTFFAKYCFDHGIQLKEIAT
IGDDETQIVDTVRRLVKNYDFIISTGGIGPTHDDITYECMAKSFNLPCELDEECKERM
RHKSDPEARLDADALKAHYQMATMPKGTNVKNYYVCDDLWVPICSISHKMYILPGIPQ
LFARMLKAFTPTLKKIYNLDKDPREYVRYFVRTHLTESQISKELKLIQDESTKVSEAI
KIGSYPHFGMGFNTVSILGEKKDDSYLKSIVNRVVNNLEGEVISSELENKFSNQES"
gene 619858..622134
/gene="SPT21"
/locus_tag="YMR179W"
/db_xref="GeneID:855217"
mRNA 619858..622134
/gene="SPT21"
/locus_tag="YMR179W"
/product="Spt21p"
/transcript_id="NM_001182685.1"
/db_xref="GI:296147296"
/db_xref="GeneID:855217"
CDS 619858..622134
/gene="SPT21"
/locus_tag="YMR179W"
/note="Protein with a role in transcriptional silencing;
required for normal transcription at several loci
including HTA2-HTB2 and HHF2-HHT2, but not required at the
other histone loci; functionally related to Spt10p;
localizes to nuclear foci that become diffuse upon DNA
replication stress"
/codon_start=1
/product="Spt21p"
/protein_id="NP_013904.1"
/db_xref="GI:6323833"
/db_xref="SGD:S000004791"
/db_xref="GeneID:855217"
/translation="MSELSQMTLKILYTLDNGSNGSYLARSRAPKQVRVANIPSPFPT
DSNEQTELRIGAIHLKTILHEIYLNSPEVLDHDTLKDGYDYNLYYRDICEVDEPLVSL
GLLSGLRKKFHKNSPYQYTENNIGEEESEERDEVTEEEYEDESFIVTGRVCSNVSALL
RRSYSNISNKKGRVVNNQIPEETLEVKLRFTKVITNLRTSGNNTTNSRISCLQMPSSL
PSATLPFTPKSQSLFKTNQIKNSRNARTTITINNTNSGTVGRRQTNPMPAPKAVRTQS
LPIWNLKPNIANTGFPRNSIAHKIYLADRKTEANQQNNQHQNIAYEINTLQNDNTIQR
TKIDDSVSKRFDFMLNKRKSTKKVSPGIATIAKKPASININPKQPPKTSGEKKANDKQ
TIVKVKNSNSKNSAKSTQAGCRRSSVIEHLNDHDDSILSDILSEPGIEGQKLQQKQKG
RKISLTSENDKENIPPQSITSKENKLEGDLDFNAEFPMSDFSDVVFKDEMGWFSNFNC
NFFESPTSASASQLNQQNLKPSITLNDPNTCNTIALENEDVSELETAQNNKISLPSDV
DKTSPIDSLSIPLIELTHSSSTTNMQRISIKEGSTLNITDSNNATPCDNDIKDRKASV
IDSDNTKPQAGLINFSTPADQPASDNNVTASKKLTSMLETQQSKRSHEEVLDEEEEEE
ALKKQKAIPSSPCGMFNYHQPMELSEDIVEEEQGHNIGDDNESDKTNDLFSTFIHSGI
RVSQVVTSPIGEFQSIKH"
gene complement(622251..623213)
/gene="CTL1"
/locus_tag="YMR180C"
/gene_synonym="CTH1"
/db_xref="GeneID:855218"
mRNA complement(622251..623213)
/gene="CTL1"
/locus_tag="YMR180C"
/gene_synonym="CTH1"
/product="Ctl1p"
/transcript_id="NM_001182686.1"
/db_xref="GI:296147297"
/db_xref="GeneID:855218"
CDS complement(622251..623213)
/gene="CTL1"
/locus_tag="YMR180C"
/gene_synonym="CTH1"
/EC_number="3.1.3.33"
/note="RNA 5'-triphosphatase, localizes to both the
nucleus and cytoplasm"
/codon_start=1
/product="Ctl1p"
/protein_id="NP_013905.1"
/db_xref="GI:6323834"
/db_xref="SGD:S000004792"
/db_xref="GeneID:855218"
/translation="MSDQPETPSNSRNSHENVGAKKADANVASKFRSLHISETTKPLT
STRALYKTTRNNSRGATEFHKHVCKLAWKYLACIDKSSISHIEIEMKFGVITDKRTHR
RMTPHNKPFIVQNRNGRLVSNVPEQMFSSFQELLRSKSENPSKCAPRVVKQVQKYTKD
SIYNCNNASKVGKLTSWRCSEDLRNKELKLTYIKKVRVKDFLIRYPQSSLDAKISISL
EVPEYETSAAFRNGFILQRTKSRSTYTFNDKMPLHLDLTKVTTTRRNSHQYTSHEVEV
EMDPIFKETISANDREKFNEYMCSFLNASDLIRKAAERDNMLTT"
gene complement(623616..624080)
/locus_tag="YMR181C"
/db_xref="GeneID:855219"
mRNA complement(623616..624080)
/locus_tag="YMR181C"
/product="hypothetical protein"
/transcript_id="NM_001182687.1"
/db_xref="GI:296147298"
/db_xref="GeneID:855219"
CDS complement(623616..624080)
/locus_tag="YMR181C"
/note="hypothetical protein; mRNA transcribed as part of a
bicistronic transcript with a predicted transcriptional
repressor RGM1/YMR182C; mRNA is destroyed by
nonsense-mediated decay (NMD); YMR181C is not an essential
gene"
/codon_start=1
/product="hypothetical protein"
/protein_id="NP_013906.1"
/db_xref="GI:6323835"
/db_xref="SGD:S000004793"
/db_xref="GeneID:855219"
/translation="MTPLLQAEAKMNTSLYLTESIQQHEFNLTSPQSFYSSPSVPNSK
NNSGIFSYNTANNSRVSSSDEFTTQQDGMNTIMYKNNISKTFEDDIFYCPRSLLTPEE
QVVYQEIDKYYMEQALLTQLQISQTYSSTPKEEKIVKFNPYTSKSFSPASSE"
gene complement(624532..625167)
/gene="RGM1"
/locus_tag="YMR182C"
/db_xref="GeneID:855220"
mRNA complement(624532..625167)
/gene="RGM1"
/locus_tag="YMR182C"
/product="Rgm1p"
/transcript_id="NM_001182688.1"
/db_xref="GI:296147299"
/db_xref="GeneID:855220"
CDS complement(624532..625167)
/gene="RGM1"
/locus_tag="YMR182C"
/note="Putative zinc finger DNA binding transcription
factor; contains two N-terminal C2H2 zinc fingers and
C-terminal proline rich domain; overproduction impairs
cell growth and induces expression of genes involved in
monosaccharide catabolism and aldehyde metabolism;
regulates expression of of Y-prime telomeric elements and
subtelomeric COS genes; RGM1 has a paralog, USV1, that
arose from the whole genome duplication"
/codon_start=1
/product="Rgm1p"
/protein_id="NP_013907.1"
/db_xref="GI:6323836"
/db_xref="SGD:S000004794"
/db_xref="GeneID:855220"
/translation="MRGKQPKRNKDNASVKRNYRCVGYPDCNMSFNRTEHLARHIRKH
TGEKPFQCNICLKFFSRIDNLRQHQSSVHSDVDLMSLRRLQQSANSTANDPNATRMFP
QLRPYGIVVQPAPVPYNLPISTPASPQDTISLYAPPYFPHPMPSAPIPLPHQPPPLPI
YSYMQPLFLNHTPIQNHNIVELPPDSSDTPASPSKVQSFDQAKDASPNAKK"
gene 625811..625897
/locus_tag="YMR182W-A"
/db_xref="GeneID:1466502"
mRNA 625811..625897
/locus_tag="YMR182W-A"
/product="hypothetical protein"
/transcript_id="NM_001184615.1"
/db_xref="GI:296147300"
/db_xref="GeneID:1466502"
CDS 625811..625897
/locus_tag="YMR182W-A"
/codon_start=1
/product="hypothetical protein"
/protein_id="NP_878144.1"
/db_xref="GI:33438856"
/db_xref="SGD:S000028693"
/db_xref="GeneID:1466502"
/translation="MRKPSAFHACNIIFLPLVKCASATIMLN"
gene 626349..626654
/locus_tag="snR83"
/db_xref="GeneID:9164955"
ncRNA 626349..626654
/locus_tag="snR83"
/ncRNA_class="snoRNA"
/product="SNR83"
/note="H/ACA box small nucleolar RNA (snoRNA); guides
pseudouridylation of small subunit (SSU) rRNA at positions
U1290 and U1415"
/db_xref="SGD:S000028468"
/db_xref="GeneID:9164955"
gene complement(626921..627808)
/gene="SSO2"
/locus_tag="YMR183C"
/db_xref="GeneID:855221"
mRNA complement(626921..627808)
/gene="SSO2"
/locus_tag="YMR183C"
/product="Sso2p"
/transcript_id="NM_001182689.1"
/db_xref="GI:296147301"
/db_xref="GeneID:855221"
CDS complement(626921..627808)
/gene="SSO2"
/locus_tag="YMR183C"
/note="Plasma membrane t-SNARE involved in fusion of
secretory vesicles at the plasma membrane; syntaxin
homolog that is functionally redundant with Sso1p"
/codon_start=1
/product="Sso2p"
/protein_id="NP_013908.1"
/db_xref="GI:6323837"
/db_xref="SGD:S000004795"
/db_xref="GeneID:855221"
/translation="MSNANPYENNNPYAENYEMQEDLNNAPTGHSDGSDDFVAFMNKI
NSINANLSRYENIINQIDAQHKDLLTQVSEEQEMELRRSLDDYISQATDLQYQLKADI
KDAQRDGLHDSNKQAQAENCRQKFLKLIQDYRIIDSNYKEESKEQAKRQYTIIQPEAT
DEEVEAAINDVNGQQIFSQALLNANRRGEAKTALAEVQARHQELLKLEKTMAELTQLF
NDMEELVIEQQENVDVIDKNVEDAQQDVEQGVGHTNKAVKSARKARKNKIRCLIICFI
IFAIVVVVVVVPSVVETRK"
gene 628189..628785
/gene="ADD37"
/locus_tag="YMR184W"
/db_xref="GeneID:855222"
mRNA 628189..628785
/gene="ADD37"
/locus_tag="YMR184W"
/product="Add37p"
/transcript_id="NM_001182690.1"
/db_xref="GI:296147302"
/db_xref="GeneID:855222"
CDS 628189..628785
/gene="ADD37"
/locus_tag="YMR184W"
/note="hypothetical protein; involved in ER-associated
protein degradation; green fluorescent protein
(GFP)-fusion protein localizes to the cytoplasm and is
induced in response to the DNA-damaging agent MMS; YMR184W
is not an essential gene; protein abundance increases in
response to DNA replication stress"
/codon_start=1
/product="Add37p"
/protein_id="NP_013909.1"
/db_xref="GI:6323838"
/db_xref="SGD:S000004796"
/db_xref="GeneID:855222"
/translation="MAIKPTKSFQNCLEAEVPGYNDCPTVLFSIDPNSGPRSKSKQRT
KSKRCVSGRLATEVLDLYGNTKTATTPPPVLRRPSVTAAQQESACEGVLVKDQGDRQL
QPILCSKEELVAKINDLCVCGSKLSSKELEFYKKKLDSNITKILQNEHTKTVLSQIFN
EKDKNMAVKTIKHWMVTDTTISNWCPAFLKIFENAMPN"
gene 629025..631970
/locus_tag="YMR185W"
/db_xref="GeneID:855223"
mRNA 629025..631970
/locus_tag="YMR185W"
/product="hypothetical protein"
/transcript_id="NM_001182691.1"
/db_xref="GI:296147303"
/db_xref="GeneID:855223"
CDS 629025..631970
/locus_tag="YMR185W"
/note="hypothetical protein; conflicting evidence on
whether null mutant is viable with elongated buds, or
inviable"
/codon_start=1
/product="hypothetical protein"
/protein_id="NP_013910.1"
/db_xref="GI:6323839"
/db_xref="SGD:S000004797"
/db_xref="GeneID:855223"
/translation="MNEDKEQKINIHDILNTRPKLTKKTALDVFFEDLDDNVITPINE
YVLDSGSSSSSSIYQALKCSNNNEFVAVLLQKFQNLHIHVLEQQRRLIESKSDLLPIS
LHDMKYVDELINLLIIHGIDANLSPTMKIPFDSKRINTFKKGQKSAEYETPRWHTINN
DTLSQVITVFYNVLTSERSSDYLREIISKGSAYANILLGLIVLHLQLPNRYSSQMITN
LEDTQETYTLFGVYTLLVETIQDEKVREPILSKLTTLTLRRPENGLISLIDFVLGVRD
AEDIDIEKFNRIYQILMSKPKTMTNLQYLTELFKQIYDGLTFVNRPILVTCLNGLILK
FYLRNKRIVNDFLFKKVRSIIFNSPLTDHTAKELNDVINVLISLSKNSSSDLLNDLVT
SCPDEDGTTPGQFFLYVWIYALFLKKNQKLDPLEINKLSISDNKSTDSIHFPEQSSSK
YYEVVLSLLKSLIVITENFQYLNVLSLNLLNFEHEKWKYLIDLDTQLPYISVKNTDMA
ELFFEKGSKNSQISEFLQDMDLSIELFMEFLVLLNDEEQSKTLFLDILKRWVHHTKKS
EKRSSDNHSGMPSVTDNALILMDLKLLECMNNRFKTKIVNKPKDVLIVIDQLIDVVQE
KDETIQEVEADSDDEVEEGEETEELDPNENSSYKIILQLLSTVLSESSSSILLQNSYI
LKSISRKLQSFNTNASEIDALLASIDNILINGHTTERNDNIEIEMDEERLDKAITSLH
DPLVPIKSYGLTELRHLAEKKSPVISLEKVLQIHLDYLKNMDPFIYLNVIKGLTTLCE
LEPETILPLLAEFYANKKKKNRLDDVLKVGEVFINYIQRQNELFQGKLAYLIIDTCLS
IVRPNDSKPLDNRWRMSSMSILGMCLQINARGVSDRIRDMLDCVFGILQLEQPQNHLK
DKDDSFLMRRSAVHLIHDLLYSTGFDLLPFEYNYDKLKTLLSYVRDQDEDYMVCEQID
KLLTVLDSL"
gene 632355..634472
/gene="HSC82"
/locus_tag="YMR186W"
/gene_synonym="HSP90"
/db_xref="GeneID:855224"
mRNA 632355..634472
/gene="HSC82"
/locus_tag="YMR186W"
/gene_synonym="HSP90"
/product="Hsc82p"
/transcript_id="NM_001182692.1"
/db_xref="GI:296147304"
/db_xref="GeneID:855224"
CDS 632355..634472
/gene="HSC82"
/locus_tag="YMR186W"
/gene_synonym="HSP90"
/note="Cytoplasmic chaperone of the Hsp90 family,
redundant in function and nearly identical with Hsp82p,
and together they are essential; expressed constitutively
at 10-fold higher basal levels than HSP82 and induced 2-3
fold by heat shock; contains two acid-rich unstructured
regions that promote the solubility of chaperone-substrate
complexes"
/codon_start=1
/product="Hsp90 family chaperone HSC82"
/protein_id="NP_013911.1"
/db_xref="GI:6323840"
/db_xref="SGD:S000004798"
/db_xref="GeneID:855224"
/translation="MAGETFEFQAEITQLMSLIINTVYSNKEIFLRELISNASDALDK
IRYQALSDPKQLETEPDLFIRITPKPEEKVLEIRDSGIGMTKAELINNLGTIAKSGTK
AFMEALSAGADVSMIGQFGVGFYSLFLVADRVQVISKNNEDEQYIWESNAGGSFTVTL
DEVNERIGRGTVLRLFLKDDQLEYLEEKRIKEVIKRHSEFVAYPIQLLVTKEVEKEVP
IPEEEKKDEEKKDEDDKKPKLEEVDEEEEEKKPKTKKVKEEVQELEELNKTKPLWTRN
PSDITQEEYNAFYKSISNDWEDPLYVKHFSVEGQLEFRAILFIPKRAPFDLFESKKKK
NNIKLYVRRVFITDEAEDLIPEWLSFVKGVVDSEDLPLNLSREMLQQNKIMKVIRKNI
VKKLIEAFNEIAEDSEQFDKFYSAFAKNIKLGVHEDTQNRAALAKLLRYNSTKSVDEL
TSLTDYVTRMPEHQKNIYYITGESLKAVEKSPFLDALKAKNFEVLFLTDPIDEYAFTQ
LKEFEGKTLVDITKDFELEETDEEKAEREKEIKEYEPLTKALKDILGDQVEKVVVSYK
LLDAPAAIRTGQFGWSANMERIMKAQALRDSSMSSYMSSKKTFEISPKSPIIKELKKR
VDEGGAQDKTVKDLTNLLFETALLTSGFSLEEPTSFASRINRLISLGLNIDEDEETET
APEASTEAPVEEVPADTEMEEVD"
rep_origin 634481..634715
/note="ARS1324;
Autonomously Replicating Sequence"
/db_xref="SGD:S000118375"
gene complement(634689..635984)
/locus_tag="YMR187C"
/db_xref="GeneID:855225"
mRNA complement(634689..635984)
/locus_tag="YMR187C"
/product="hypothetical protein"
/transcript_id="NM_001182693.1"
/db_xref="GI:296147305"
/db_xref="GeneID:855225"
CDS complement(634689..635984)
/locus_tag="YMR187C"
/note="hypothetical protein; YMR187C is not an essential
gene"
/codon_start=1
/product="hypothetical protein"
/protein_id="NP_013912.1"
/db_xref="GI:6323841"
/db_xref="SGD:S000004799"
/db_xref="GeneID:855225"
/translation="MTPPHFFLSLIKKRCICWICLEESTYDSTWLQHTCGCNLQIHKR
CYIRWLYQMHVELFLPNTVDLPKDADLPIITCLKCLVDGHHDFMTTFSLTEIWETRPI
WGQKSVPFQNDYVFNLMSLYTKRDNHPPYVLVKFGECPQCKKTNFIKRPTVTIQSSVL
SLFYQWQKITRYVIPLGITSLFLLNPEKTSFDIGLWQLRCLFPENVLRNMLNISTTKA
LDVYAQTERGLLSIPLTSSIIIYGFIHYLSNISNVSANAILFKWVYLSIVKTAGNKYY
KGIGLPKIILYSNLATFCYNFTFKRLVDLIYRRLINKGGKYLYHGNFENSSNSVPAEE
FFIRRNWYAILAEKILWPFVGKCTGGLLLNAFLWIQRKFKIEWTPNCSPSEFRMIFNI
IGCGTAAIGWSSLKLYASYKRCQELEKINEFIEQSCKGE"
gene complement(636291..637004)
/gene="MRPS17"
/locus_tag="YMR188C"
/db_xref="GeneID:855226"
mRNA complement(636291..637004)
/gene="MRPS17"
/locus_tag="YMR188C"
/product="mitochondrial 37S ribosomal protein MRPS17"
/transcript_id="NM_001182694.1"
/db_xref="GI:296147306"
/db_xref="GeneID:855226"
CDS complement(636291..637004)
/gene="MRPS17"
/locus_tag="YMR188C"
/note="Mitochondrial ribosomal protein of the small
subunit"
/codon_start=1
/product="mitochondrial 37S ribosomal protein MRPS17"
/protein_id="NP_013913.1"
/db_xref="GI:6323842"
/db_xref="SGD:S000004800"
/db_xref="GeneID:855226"
/translation="MARQNFLGLVVSQGKMQKTVKVRVETKVFNKKINKELFHRRDYL
VHDEGEISREGDLVRIEATRPLSKRKFFAIAEIIRNKGQQFALYESEAQLSVAKEEAQ
KAKEFLDKRSVRENKLNEKTTLLRDIRTIQDALSSGSTPKELLEIKQRYGIQDFSQET
VRQLLQLDISGLEVNLEKQRSLIDRIQTRLSELLSNDLKCDQFLKDHGVEDPLTLKKN
IKKNLLRKHVMMDMQQPSQ"
gene 637500..640604
/gene="GCV2"
/locus_tag="YMR189W"
/gene_synonym="GSD2"
/db_xref="GeneID:855227"
mRNA 637500..640604
/gene="GCV2"
/locus_tag="YMR189W"
/gene_synonym="GSD2"
/product="glycine decarboxylase subunit P"
/transcript_id="NM_001182695.1"
/db_xref="GI:296147307"
/db_xref="GeneID:855227"
CDS 637500..640604
/gene="GCV2"
/locus_tag="YMR189W"
/gene_synonym="GSD2"
/EC_number="1.4.4.2"
/note="P subunit of the mitochondrial glycine
decarboxylase complex, required for the catabolism of
glycine to 5,10-methylene-THF; expression is regulated by
levels of 5,10-methylene-THF in the cytoplasm"
/codon_start=1
/product="glycine decarboxylase subunit P"
/protein_id="NP_013914.1"
/db_xref="GI:6323843"
/db_xref="SGD:S000004801"
/db_xref="GeneID:855227"
/translation="MLRTRVTALLCRATVRSSTNYVSLARTRSFHSQSILLKTAATDI
TSTQYSRIFNPDLKNIDRPLDTFARRHLGPSPSDVKKMLKTMGYSDLNAFIEELVPPN
ILKRRPLKLEAPSKGFCEQEMLQHLEKIANKNHYKVKNFIGKGYYGTILPPVIQRNLL
ESPEWYTSYTPYQPEISQGRLEALLNFQTVVSDLTGLPVANASLLDEGTAAGEAMLLS
FNISRKKKLKYVIDKKLHQQTKSVLHTRAKPFNIEIIEVDCSDIKKAVDVLKNPDVSG
CLVQYPATDGSILPPDSMKQLSDALHSHKSLLSVASDLMALTLLKPPAHYGADIVLGS
SQRFGVPMGYGGPHAAFFAVIDKLNRKIPGRIVGISKDRLGKTALRLALQTREQHIKR
DKATSNICTAQALLANVASSYCVYHGPKGLQNISRRIFSLTSILANAIENDSCPHELI
NKTWFDTLTIKLGNGISSEQLLDKALKEFNINLFAVDTTTISLALDETTTKADVENLL
KVFDIENSSQFLSEDYSNSFPREFQRTDEILRNEVFHMHHSETAMLRYLHRLQSRDLS
LANSMIPLGSCTMKLNSTVEMMPITWPQFSNIHPFQPSNQVQGYKELITSLEKDLCSI
TGFDGISLQPNSGAQGEYTGLRVIRSYLESKGENHRNVCLIPVSAHGTNPASAAMAGL
KVVPVNCLQDGSLDLVDLKNKAEQHSKELAAVMITYPSTYGLFEPGIQHAIDIVHSFG
GQVYLDGANMNAQVGLTSPGDLGADVCHLNLHKTFSIPHGGGGPAGAPICVKSHLIPH
LPKHDVVDMITGIGGSKSIDSVSSAPYGNALVLPISYAYIKMMGNEGLPFSSVIAMLN
SNYMMTRLKDHYKILFVNEMSTLKHCAHEFIVDLREYKAKGVEAIDVAKRLQDYGFHA
PTLAFPVPGTLMIEPTESENLEELDRFCDAMISIKEEINALVAGQPKGQILKNAPHSL
EDLITSSNWDTRGYTREEAAYPLPFLRYNKFWPTVARLDDTYGDMNLICTCPSVEEIA
NETE"
gene complement(640915..645258)
/gene="SGS1"
/locus_tag="YMR190C"
/db_xref="GeneID:855228"
mRNA complement(640915..645258)
/gene="SGS1"
/locus_tag="YMR190C"
/product="Sgs1p"
/transcript_id="NM_001182696.1"
/db_xref="GI:296147308"
/db_xref="GeneID:855228"
CDS complement(640915..645258)
/gene="SGS1"
/locus_tag="YMR190C"
/EC_number="3.6.1.-"
/note="Nucleolar DNA helicase of the RecQ family; involved
in genome integrity maintenance; regulates chromosome
synapsis and meiotic joint molecule/crossover formation;
potential role as repressor of a subset of rapamycin
responsive genes; rapidly lost in response to rapamycin in
Rrd1p-dependent manner; similar to human BLM and WRN
proteins implicated in Bloom and Werner syndromes; forms
nuclear foci upon DNA replication stress"
/codon_start=1
/product="Sgs1p"
/protein_id="NP_013915.1"
/db_xref="GI:6323844"
/db_xref="SGD:S000004802"
/db_xref="GeneID:855228"
/translation="MVTKPSHNLRREHKWLKETATLQEDKDFVFQAIQKHIANKRPKT
NSPPTTPSKDECGPGTTNFITSIPASGPTNTATKQHEVMQTLSNDTEWLSYTATSNQY
ADVPMVDIPASTSVVSNPRTPNGSKTHNFNTFRPHMASSLVENDSSRNLGSRNNNKSV
IDNSSIGKQLENDIKLEVIRLQGSLIMALKEQSKLLLQKCSIIESTSLSEDAKRLQLS
RDIRPQLSNMSIRIDSLEKEIIKAKKDGMSKDQSKGRSQVSSQDDNIISSILPSPLEY
NTSSRNSNLTSTTATTVTKALAITGAKQNITNNTGKNSNNDSNNDDLIQVLDDEDDID
CDPPVILKEGAPHSPAFPHLHMTSEEQDELTRRRNMRSREPVNYRIPDRDDPFDYVMG
KSLRDDYPDVEREEDELTMEAEDDAHSSYMTTRDEEKEENELLNQSDFDFVVNDDLDP
TQDTDYHDNMDVSANIQESSQEGDTRSTITLSQNKNVQVILSSPTAQSVPSNGQNQIG
VEHIDLLEDDLEKDAILDDSMSFSFGRQHMPMSHSDLELIDSEKENEDFEEDNNNNGI
EYLSDSDLERFDEERENRTQVADIQELDNDLKIITERKLTGDNEHPPPSWSPKIKREK
SSVSQKDEEDDFDDDFSLSDIVSKSNLSSKTNGPTYPWSDEVLYRLHEVFKLPGFRPN
QLEAVNATLQGKDVFVLMPTGGGKSLCYQLPAVVKSGKTHGTTIVISPLISLMQDQVE
HLLNKNIKASMFSSRGTAEQRRQTFNLFINGLLDLVYISPEMISASEQCKRAISRLYA
DGKLARIVVDEAHCVSNWGHDFRPDYKELKFFKREYPDIPMIALTATASEQVRMDIIH
NLELKEPVFLKQSFNRTNLYYEVNKKTKNTIFEICDAVKSRFKNQTGIIYCHSKKSCE
QTSAQMQRNGIKCAYYHAGMEPDERLSVQKAWQADEIQVICATVAFGMGIDKPDVRFV
YHFTVPRTLEGYYQETGRAGRDGNYSYCITYFSFRDIRTMQTMIQKDKNLDRENKEKH
LNKLQQVMAYCDNVTDCRRKLVLSYFNEDFDSKLCHKNCDNCRNSANVINEERDVTEP
AKKIVKLVESIQNERVTIIYCQDVFKGSRSSKIVQANHDTLEEHGIGKSMQKSEIERI
FFHLITIRVLQEYSIMNNSGFASSYVKVGPNAKKLLTGKMEIKMQFTISAPNSRPSTS
SSFQANEDNIPVIAQKSTTIGGNVAANPPRFISAKEHLRSYTYGGSTMGSSHPITLKN
TSDLRSTQELNNLRMTYERLRELSLNLGNRMVPPVGNFMPDSILKKMAAILPMNDSAF
ATLGTVEDKYRRRFKYFKATIADLSKKRSSEDHEKYDTILNDEFVNRAAASSNGIAQS
TGTKSKFFGANLNEAKENEQIINQIRQSQLPKNTTSSKSGTRSISKSSKKSANGRRGF
RNYRGHYRGRK"
gene 645656..646777
/gene="SPG5"
/locus_tag="YMR191W"
/db_xref="GeneID:855229"
mRNA 645656..646777
/gene="SPG5"
/locus_tag="YMR191W"
/product="Spg5p"
/transcript_id="NM_001182697.1"
/db_xref="GI:296147309"
/db_xref="GeneID:855229"
CDS 645656..646777
/gene="SPG5"
/locus_tag="YMR191W"
/note="Protein required for survival at high temperature
during stationary phase; not required for growth on
nonfermentable carbon sources"
/codon_start=1
/product="Spg5p"
/protein_id="NP_013916.2"
/db_xref="GI:37362682"
/db_xref="SGD:S000004803"
/db_xref="GeneID:855229"
/translation="MAVGGNNWSMWLRMSRVHLRQITKSLDRTLISLSHGNFSHQYNR
NIFVTWWKSLFEASTAFRRASGLTVSPLTRRGIARFDHFRPVPNVSKFASFPRVPKGA
PRGLFTNWNMTTSKRLLGQRAYSTSSIKFTQEAVNNMTISLRCFFNSLGGLNQCSHSN
SCKAYQNASNVTSKQDHVQPVALKKLSQKDINFIRNLELFKIMKTQNEVVDETSAYYM
EKPGSYIEFTISEFNVNGTFSAPLSFLDPSLLADLDEMIRNYKYELKSIYSSVDMILQ
NYGSLPITFHRNKIRIHFPNSTVVETEKLIAGLNIATGVIYADTSPDISLEGTNLNAL
VNVDNSGSVWSFVKEPSFPSRSAFSPILSDASYDTYELV"
gene 647118..649280
/gene="GYL1"
/locus_tag="YMR192W"
/gene_synonym="APP2"
/db_xref="GeneID:855230"
mRNA 647118..649280
/gene="GYL1"
/locus_tag="YMR192W"
/gene_synonym="APP2"
/product="Gyl1p"
/transcript_id="NM_001182698.1"
/db_xref="GI:296147310"
/db_xref="GeneID:855230"
CDS 647118..649280
/gene="GYL1"
/locus_tag="YMR192W"
/gene_synonym="APP2"
/note="Putative GTPase activating protein (GAP) with a
role in exocytosis; stimulates Gyp5p GAP activity on
Ypt1p, colocalizes with Gyp5p at sites of polarized
growth; interacts with Gyp5p, Rvs161p, and Rvs167p;
involved in recruiting Rvs167p to the bud tip during
polarized growth; increases in abundance and relocalizes
from bud neck to cytoplasm upon DNA replication stress"
/codon_start=1
/product="Gyl1p"
/protein_id="NP_013917.1"
/db_xref="GI:6323846"
/db_xref="SGD:S000004804"
/db_xref="GeneID:855230"
/translation="MNSNEDIHEERIEVPRTPHQTQPEKDSDRIALRDEISVPEGDEK
AYSDEKVEMATTNASSNFGSNESAKDGESIGAFSNPHEALMQSKLREESQSKTILPSD
DLSQQLETEESKVEEALKRITSPPLPPRADCIEESASALKSSLPPVLAGNKNDQAPLD
RPQLPPRQVVNAETLHLKAPHGNATPSKSPTSAVGNSSSSTPPTLPPRRIEDPLDLAA
QKHFLASTFKRNMLFYKSEDNSIKCDLDKNILNLKEDSKKINNNEIPEEVSSFWLKVI
GDYQNILINDIETLHFQLSRGIPAAYRLVVWQLVSYAKSKSFDPIYETYLTEMAPFDV
QEFENQLKMMDEVPSEYVKRISNVLKAYLLFDPECEFSTDIAYIINMILDVCEEEANA
FGLLVRLMKVYGLRLLFLPSASEIDILCYKFDRLVEEFYPEIHNHMVEKGVRSSMFLP
GFFTTLFQKKLPTEIQPRIGDMVFLEGIDSIMRILATLLSNSRDHLLKMGFDDMLELL
KSGLLDAYIKQNDGTRGDTLLSNECMDKLLQDSMMKVAITPKTMKKYSSEYEEIHRLD
NEKEVQYKSITEKNLHLQKHVRKLENDYTSLNREHVTIANELVKNRLNIESVLNENNG
YKLQILDLKKKLDSEKKKQVLGVYVPNDLKKDLEETMKKNTQVMDENLKLQDRISELE
RLIEEIKTANKNGTLFEYSNSKNNPLGAGWSGFKKVFK"
rep_origin 649309..649552
/note="ARS1325;
Autonomously Replicating Sequence"
/db_xref="SGD:S000118376"
gene 650036..650812
/gene="MRPL24"
/locus_tag="YMR193W"
/db_xref="GeneID:855231"
mRNA 650036..650812
/gene="MRPL24"
/locus_tag="YMR193W"
/product="mitochondrial 54S ribosomal protein YmL24/YmL14"
/transcript_id="NM_001182700.1"
/db_xref="GI:296147311"
/db_xref="GeneID:855231"
CDS 650036..650812
/gene="MRPL24"
/locus_tag="YMR193W"
/note="Mitochondrial ribosomal protein of the large
subunit; two mitochondrial ribosomal proteins, YmL14 and
YmL24, have been assigned to the same gene"
/codon_start=1
/product="mitochondrial 54S ribosomal protein YmL24/YmL14"
/protein_id="NP_013918.1"
/db_xref="GI:6323847"
/db_xref="SGD:S000004806"
/db_xref="GeneID:855231"
/translation="MQKIFRPFQLTRGFTSSVKNFRQWRLIETRKIAKQPNYQVGDAK
PLHMPKERKKFPDYKYGESNIFKQSNKGLYGGSFVQFGNNISESKAKTRKKWLPNVVK
KGLWSETLNRKISIKMTAKVLKTISKEGGIDNYLTKEKSARIKELGPTGWKLRYRVLK
RKDEIENPPHKDAPIIEMAGGKKAKIYYDEIVNGSPRKISVGRRRLMSFLYPLEKLEY
RSVGKDLNYKKFVELFADVPVKDILARLEDHKFDLSTITV"
gene 651145..651910
/gene="RPL36A"
/locus_tag="YMR194W"
/gene_synonym="RPL39B"
/db_xref="GeneID:855232"
mRNA join(651145..651160,651624..651910)
/gene="RPL36A"
/locus_tag="YMR194W"
/gene_synonym="RPL39B"
/product="ribosomal 60S subunit protein L36A"
/transcript_id="NM_001182701.1"
/db_xref="GI:296147312"
/db_xref="GeneID:855232"
CDS join(651145..651160,651624..651910)
/gene="RPL36A"
/locus_tag="YMR194W"
/gene_synonym="RPL39B"
/note="Ribosomal 60S subunit protein L36A; N-terminally
acetylated; binds to 5.8 S rRNA; homologous to mammalian
ribosomal protein L36, no bacterial homolog; RPL36A has a
paralog, RPL36B, that arose from the whole genome
duplication"
/codon_start=1
/product="ribosomal 60S subunit protein L36A"
/protein_id="NP_013920.1"
/db_xref="GI:6323848"
/db_xref="SGD:S000004807"
/db_xref="GeneID:855232"
/translation="MTVKTGIAIGLNKGKKVTSMTPAPKISYKKGAASNRTKFVRSLV
REIAGLSPYERRLIDLIRNSGEKRARKVAKKRLGSFTRAKAKVEEMNNIIAASRRH"
gene 652275..652532
/locus_tag="snR11"
/db_xref="GeneID:9164951"
ncRNA 652275..652532
/locus_tag="snR11"
/ncRNA_class="snoRNA"
/product="SNR11"
/note="H/ACA box small nucleolar RNA (snoRNA); guides
pseudouridylation of large subunit (LSU) rRNA at position
U2416"
/db_xref="SGD:S000007293"
/db_xref="GeneID:9164951"
gene complement(652594..652887)
/gene="CMC4"
/locus_tag="YMR194C-B"
/db_xref="GeneID:1466503"
mRNA complement(join(652594..652775,652848..652887))
/gene="CMC4"
/locus_tag="YMR194C-B"
/product="Cmc4p"
/transcript_id="NM_001184524.1"
/db_xref="GI:296147313"
/db_xref="GeneID:1466503"
CDS complement(join(652594..652775,652848..652887))
/gene="CMC4"
/locus_tag="YMR194C-B"
/note="Protein that localizes to the mitochondrial
intermembrane space via the Mia40p-Erv1p system; contains
twin cysteine-x(9)-cysteine motifs"
/codon_start=1
/product="Cmc4p"
/protein_id="NP_878145.1"
/db_xref="GI:33438857"
/db_xref="SGD:S000028514"
/db_xref="GeneID:1466503"
/translation="MSNPCQKEACAIQDCLLSHQYDDAKCAKVIDQLYICCSKFYNDN
GKDSRSPCCPLPSLLELKMKQRKLTPGDS"
gene 654034..654417
/gene="ICY1"
/locus_tag="YMR195W"
/db_xref="GeneID:855235"
mRNA 654034..654417
/gene="ICY1"
/locus_tag="YMR195W"
/product="Icy1p"
/transcript_id="NM_001182702.1"
/db_xref="GI:296147314"
/db_xref="GeneID:855235"
CDS 654034..654417
/gene="ICY1"
/locus_tag="YMR195W"
/note="hypothetical protein, required for viability in
rich media of cells lacking mitochondrial DNA; mutants
have an invasive growth defect with elongated morphology;
induced by amino acid starvation"
/codon_start=1
/product="Icy1p"
/protein_id="NP_013922.1"
/db_xref="GI:6323851"
/db_xref="SGD:S000004808"
/db_xref="GeneID:855235"
/translation="MSSNYATPLDDEVFPLSFANYQFTEHVSLGEHYSLNTSEDAKYN
NLNGPFVVPRDTGKFDLNTSSASDETVFSLDNPQENNYKHQAMNNVQDCRMAVAAKTT
QSCDKLTDLYANAAQQNYRLWLSSF"
gene 655076..658342
/locus_tag="YMR196W"
/db_xref="GeneID:855236"
mRNA 655076..658342
/locus_tag="YMR196W"
/product="hypothetical protein"
/transcript_id="NM_001182703.1"
/db_xref="GI:296147315"
/db_xref="GeneID:855236"
CDS 655076..658342
/locus_tag="YMR196W"
/note="hypothetical protein; green fluorescent protein
(GFP)-fusion protein localizes to the cytoplasm; YMR196W
is not an essential gene"
/codon_start=1
/product="hypothetical protein"
/protein_id="NP_013923.1"
/db_xref="GI:6323852"
/db_xref="SGD:S000004809"
/db_xref="GeneID:855236"
/translation="MNKLRDKFVDSTVEEERLRENRNHEKYWYRWGPYLSERSWATVR
EDYSLNGDAWSNFPFEHANARVFRWGEDGLFGVSDNKQLVCMNVALWNGKDERLKERL
FGLTGPQGNHGEDVKELYFYLDNTPTHSYMKALYKYPFKKAFPYKELVQKNGERGYED
KEFEVYDIDGLYRDSETGDNPYFDVFFEMAKDDENPSELNFRLTIHNRSKIDSGELYI
APQLFFRNTWAFDGTRTKDKPLLERDAEAANLINMTHKKYGNCQMVFQPSPGGFSSGT
NEEEEDKEVEDIDPLLLFTDNESNLVKLFNEEKNPSEYTKDAFEEYLVQGKTDAVNPE
NKGTKACAVYHFKNIPPGEYVTVRYKFTNDPKNSIFKAQNLAVVDEDEFDLIFDNREE
EADNFYWRITPLPISDELRNLQRQAFSGLLWTKQFYNFTYDAWYNGDANVKPRPPPNR
ANGRNKNWKHLYIEDILSMPDKWEYPFFASWDTAFHCIPLAMIDPEFAKRQLDLLTRE
WYMHPNGQIPAYEWNFNDVNPPVHAWAVYRVFKIERNMYNREDRTFLERVFQKLLLNF
TWWVNRKDTEGKNVFEGGFLGLDNIGVFNRSEPLPTGGTLEQADSTGWMAFFSLQMLN
IALELAKENPVYEDIASKFFEHFILISDSMSFEYATDITGEKCKEVIKQNLWNEADKF
YYDAISWGDHKVQLPIRSLVGLIPLYASMTLEPSIIKQFRGFKKRVDWFVNNRPEIFD
RNIASMSKKGVGERLLLSLVTKERLTAILSRLLDETEFLSPYGIRSLSKYHEKHPFEM
NVNGVEYMVKYLPGESDSGMFGGNSNWRGPIWFPTSFLIMEALQRFYLYYGSDFKVEC
PVGSGDYLNLAEVAEELGYRMIHLFVPDENGERAIHYGDHSKFLSSDPYFRDYVPFFE
YFDGDTGRGLGASHQCGWTALVAKWISDVGISCVRLPRTPRSSVATTASTESSEQGPK
MKRMARRKSAKSLVNYTATILDLTEEEKRHHRIGGTHSGLTPQSSISSDKARHLMEEM
NEEEGIHETVVPEDRHNFETKLIGKLKDKVKNMKVTDKAKDEDIDPMDPMSPLNKDVS
"
gene complement(658545..659198)
/gene="VTI1"
/locus_tag="YMR197C"
/db_xref="GeneID:855237"
mRNA complement(658545..659198)
/gene="VTI1"
/locus_tag="YMR197C"
/product="Vti1p"
/transcript_id="NM_001182704.1"
/db_xref="GI:296147316"
/db_xref="GeneID:855237"
CDS complement(658545..659198)
/gene="VTI1"
/locus_tag="YMR197C"
/note="Protein involved in cis-Golgi membrane traffic;
v-SNARE that interacts with two t-SNARES, Sed5p and
Pep12p; required for multiple vacuolar sorting pathways"
/codon_start=1
/product="Vti1p"
/protein_id="NP_013924.1"
/db_xref="GI:6323853"
/db_xref="SGD:S000004810"
/db_xref="GeneID:855237"
/translation="MSSLLISYESDFKTTLEQAKASLAEAPSQPLSQRNTTLKHVEQQ
QDELFDLLDQMDVEVNNSIGDASERATYKAKLREWKKTIQSDIKRPLQSLVDSGDRDR
LFGDLNASNIDDDQRQQLLSNHAILQKSGDRLKDASRIANETEGIGSQIMMDLRSQRE
TLENARQTLFQADSYVDKSIKTLKTMTRRLVANKFISYAIIAVLILLILLVLFSKFK"
gene 659745..661529
/gene="CIK1"
/locus_tag="YMR198W"
/db_xref="GeneID:855238"
mRNA 659745..661529
/gene="CIK1"
/locus_tag="YMR198W"
/product="Cik1p"
/transcript_id="NM_001182705.1"
/db_xref="GI:296147317"
/db_xref="GeneID:855238"
CDS 659745..661529
/gene="CIK1"
/locus_tag="YMR198W"
/note="Kinesin-associated protein required for both
karyogamy and mitotic spindle organization, interacts
stably and specifically with Kar3p and may function to
target this kinesin to a specific cellular role; has
similarity to Vik1p"
/codon_start=1
/product="Cik1p"
/protein_id="NP_013925.1"
/db_xref="GI:6323854"
/db_xref="SGD:S000004811"
/db_xref="GeneID:855238"
/translation="MNNSKIPKLSFHSDPNNVTRDFPKTKRQKVQKREMDMILTPNNN
KLNILHSSGSGIRRCYTDDTSATYTKKLTFGGDPKIIERVKNNERKVRKDIDSLLNAI
SEIEKESVRIHARELPAITLELDAKVKACRELQNEIDGLSTEMDLKDNQCDLQRKNVE
LSSKNIVSMHAVKVQEFENDLEEELSNAKREWTYKLMEVENLKPDERLTDEMRQLKTE
FEEVNRKLFILQNENENECKNYKKELDKKFEIFKKVKNDARIELDGEQERLSKVLKDL
QDTHGELKENIKTCRDEFNDFEKRIGEAEVNFHSMELAVVPLKKKLASTSQALTQVQE
EKKQVEGEANNWKKKYVNELEKVQQELYTRQNLATSIEEIKGYTRCFAYANERQMPDE
FHINYVDRCICENSGEKRVQVFDRVVLEEIHKDHKRLYNECIPFLEKYISKLINCSII
VVSQQPTAPMKKTLLKQLIEQYGENYKMTLNILHLDGSIKHSDVGLDNPTEIRDLSQD
EECMNILTLDTKLGKDEESHSMNIYIGSMSTVQLNRELDDAPSVLSHILTKTKQCFVF
KINAGENIEKALALAGKLKRTITLPQLD"
gene 662644..664284
/gene="CLN1"
/locus_tag="YMR199W"
/db_xref="GeneID:855239"
mRNA 662644..664284
/gene="CLN1"
/locus_tag="YMR199W"
/product="Cln1p"
/transcript_id="NM_001182706.1"
/db_xref="GI:296147318"
/db_xref="GeneID:855239"
CDS 662644..664284
/gene="CLN1"
/locus_tag="YMR199W"
/note="G1 cyclin involved in regulation of the cell cycle;
activates Cdc28p kinase to promote the G1 to S phase
transition; late G1 specific expression depends on
transcription factor complexes, MBF (Swi6p-Mbp1p) and SBF
(Swi6p-Swi4p)"
/codon_start=1
/product="Cln1p"
/protein_id="NP_013926.1"
/db_xref="GI:6323855"
/db_xref="SGD:S000004812"
/db_xref="GeneID:855239"
/translation="MNHSEVKTGLIVTAKQTYYPIELSNAELLTHYETIQEYHEEISQ
NVLVQSSKTKPDIKLIDQQPEMNPHQTREAIVTFLYQLSVMTRVSNGIFFHAVRFYDR
YCSKRVVLKDQAKLVVGTCLWLAAKTWGGCNHIINNVSIPTGGRFYGPNPRARIPRLS
ELVHYCGGSDLFDESMFIQMERHILDTLNWDVYEPMINDYILNVDENCLIQYELYKNQ
LQNNNSNGKEWSCKRKSQSSDDSDATVEEHISSSPQSTGLDGDTTTMDEDEELNSKIK
LINLKRFLIDLSCWQYNLLKFELYEICNGMFSIINKFTNQDQGPFLSMPIGNDINSNT
QTQVFSIIINGIVNSPPSLVEVYKEQYGIVPFILQVKDYNLELQKKLQLASTIDLTRK
IAVNSRYFDQNASSSSVSSPSTYSSGTNYTPMRNFSAQSDNSVFSTTNIDHSSPITPH
MYTFNQFKNESACDSAISVSSLPNQTQNGNMPLSSNYQNMMLEERNKENRIPNSSSAE
IPQRAKFMTTGIFQNTGELTNRASSISLSLRNHNSSQL"
gene 664752..665522
/gene="ROT1"
/locus_tag="YMR200W"
/db_xref="GeneID:855240"
mRNA 664752..665522
/gene="ROT1"
/locus_tag="YMR200W"
/product="Rot1p"
/transcript_id="NM_001182707.1"
/db_xref="GI:296147319"
/db_xref="GeneID:855240"
CDS 664752..665522
/gene="ROT1"
/locus_tag="YMR200W"
/note="Molecular chaperone involved in protein folding in
the ER; mutation causes defects in cell wall synthesis and
in lysis of autophagic bodies, suppresses tor2 mutations,
and is synthetically lethal with kar2-1 and with rot2
mutations; involved in N-linked glycosylation and
O-mannosylation"
/codon_start=1
/product="Rot1p"
/protein_id="NP_013927.1"
/db_xref="GI:6323856"
/db_xref="SGD:S000004813"
/db_xref="GeneID:855240"
/translation="MWSKKFTLKKLILGGYLFAQKVYCEDESNSIYGTWSSKSNQVFT
GPGFYDPVDELLIEPSLPGLSYSFTEDGWYEEATYQVSGNPRNPTCPMASLIYQHGTY
NISENGTLVLNPIEVDGRQLFSDPCNDDGVSTYSRYNQTETFKEYAVGIDPYHGIYTL
QLYQYDGTPMQPLYLAYRPPMMLPTETLNPTSSATSTDDPSSNKKRSLRSLVRRSLEN
RHKTNAIKRQNTSFLTSNAIWYISAGMLGVGSLLFLAF"
gene complement(665845..667044)
/gene="RAD14"
/locus_tag="YMR201C"
/db_xref="GeneID:855241"
mRNA complement(join(665845..666933,667018..667044))
/gene="RAD14"
/locus_tag="YMR201C"
/product="Rad14p"
/transcript_id="NM_001182708.1"
/db_xref="GI:296147320"
/db_xref="GeneID:855241"
CDS complement(join(665845..666933,667018..667044))
/gene="RAD14"
/locus_tag="YMR201C"
/note="Protein that recognizes and binds damaged DNA
during nucleotide excision repair; subunit of Nucleotide
Excision Repair Factor 1 (NEF1); contains zinc finger
motif; homolog of human XPA protein"
/codon_start=1
/product="Rad14p"
/protein_id="NP_013928.1"
/db_xref="GI:6323857"
/db_xref="SGD:S000004814"
/db_xref="GeneID:855241"
/translation="MTPEQKAKLEANRKLAIERLRKRGILSSDQLNRIESRNEPLKTR
PLAVTSGSNRDDNAAAAVHVPNHNGQPSALANTNTNTTSLYGSGVVDGSKRDASVLDK
RPTDRIRPSIRKQDYIEYDFATMQNLNGGYINPKDKLPNSDFTDDQEFESEFGSKKQK
TLQDWKKEQLERKMLYENAPPPEHISKAPKCIECHINIEMDPVLHDVFKLQVCKQCSK
EHPEKYALLTKTECKEDYFLTDPELNDEDLFHRLEKPNPHSGTFARMQLFVRCEVEAF
AFKKWGGEEGLDEEWQRREEGKAHRREKKYEKKIKEMRLKTRAQEYTNRLREKKHGKA
HIHHFSDPVDGGIDEDGYQIQRRRCTDCGLETEEIDI"
gene complement(667288..667456)
/locus_tag="RNA170"
/db_xref="GeneID:9164961"
ncRNA complement(667288..667456)
/locus_tag="RNA170"
/ncRNA_class="other"
/product="RNA170"
/note="RNA polymerase III transcribed RNA of unknown
function, conserved in other yeast species"
/db_xref="SGD:S000114171"
/db_xref="GeneID:9164961"
gene 667537..668205
/gene="ERG2"
/locus_tag="YMR202W"
/gene_synonym="END11"
/db_xref="GeneID:855242"
mRNA 667537..668205
/gene="ERG2"
/locus_tag="YMR202W"
/gene_synonym="END11"
/product="C-8 sterol isomerase ERG2"
/transcript_id="NM_001182709.1"
/db_xref="GI:296147321"
/db_xref="GeneID:855242"
CDS 667537..668205
/gene="ERG2"
/locus_tag="YMR202W"
/gene_synonym="END11"
/EC_number="5.-.-.-"
/note="C-8 sterol isomerase, catalyzes the isomerization
of the delta-8 double bond to the delta-7 position at an
intermediate step in ergosterol biosynthesis"
/codon_start=1
/product="C-8 sterol isomerase ERG2"
/protein_id="NP_013929.1"
/db_xref="GI:6323858"
/db_xref="SGD:S000004815"
/db_xref="GeneID:855242"
/translation="MKFFPLLLLIGVVGYIMNVLFTTWLPTNYMFDPKTLNEICNSVI
SKHNAAEGLSTEDLLQDVRDALASHYGDEYINRYVKEEWVFNNAGGAMGQMIILHASV
SEYLILFGTAVGTEGHTGVHFADDYFTILHGTQIAALPYATEAEVYTPGMTHHLKKGY
AKQYSMPGGSFALELAQGWIPCMLPFGFLDTFSSTLDLYTLYRTVYLTARDMGKNLLQ
NKKF"
gene 668492..669655
/gene="TOM40"
/locus_tag="YMR203W"
/gene_synonym="ISP42; MOM38"
/db_xref="GeneID:855243"
mRNA 668492..669655
/gene="TOM40"
/locus_tag="YMR203W"
/gene_synonym="ISP42; MOM38"
/product="Tom40p"
/transcript_id="NM_001182710.1"
/db_xref="GI:296147322"
/db_xref="GeneID:855243"
CDS 668492..669655
/gene="TOM40"
/locus_tag="YMR203W"
/gene_synonym="ISP42; MOM38"
/note="Component of the TOM (translocase of outer
membrane) complex responsible for recognition and initial
import steps for all mitochondrially directed proteins;
constitutes the core element of the protein conducting
pore"
/codon_start=1
/product="Tom40p"
/protein_id="NP_013930.1"
/db_xref="GI:6323859"
/db_xref="SGD:S000004816"
/db_xref="GeneID:855243"
/translation="MSAPTPLAEASQIPTIPALSPLTAKQSKGNFFSSNPISSFVVDT
YKQLHSHRQSLELVNPGTVENLNKEVSRDVFLSQYFFTGLRADLNKAFSMNPAFQTSH
TFSIGSQALPKYAFSALFANDNLFAQGNIDNDLSVSGRLNYGWDKKNISKVNLQISDG
QPTMCQLEQDYQASDFSVNVKTLNPSFSEKGEFTGVAVASFLQSVTPQLALGLETLYS
RTDGSAPGDAGVSYLTRYVSKKQDWIFSGQLQANGALIASLWRKVAQNVEAGIETTLQ
AGMVPITDPLMGTPIGIQPTVEGSTTIGAKYEYRQSVYRGTLDSNGKVACFLERKVLP
TLSVLFCGEIDHFKNDTKIGCGLQFETAGNQELLMLQQGLDADGNPLQALPQL"
gene complement(670063..671325)
/gene="INP1"
/locus_tag="YMR204C"
/db_xref="GeneID:855244"
mRNA complement(670063..671325)
/gene="INP1"
/locus_tag="YMR204C"
/product="Inp1p"
/transcript_id="NM_001182711.1"
/db_xref="GI:296147323"
/db_xref="GeneID:855244"
CDS complement(670063..671325)
/gene="INP1"
/locus_tag="YMR204C"
/note="Peripheral membrane protein of peroxisomes involved
in peroxisomal inheritance; recruitment to peroxisomes is
mediated by interaction with Pex3p at the peroxisomal
membrane"
/codon_start=1
/product="Inp1p"
/protein_id="NP_013931.1"
/db_xref="GI:6323860"
/db_xref="SGD:S000004817"
/db_xref="GeneID:855244"
/translation="MVLSRGETKKNSVRLTAKQEKKPQSTFQTLKQSLKLSNNKKLKQ
DSTQHSNDTNKSVKAKKNGTSSKKTGTQRKRISTQRFSLFTYGNVQVMNSFVPIHNDI
PNSSCIRRNSQVSANNVTESSGVFFNDTQSQDSQNTIKLKPTSLMAKGPIEIYQICTG
FDKLKENIAPFQKSSKASSHDGHVVNYLSIGRHGDIVHPVLPKLQITRLNGAGFKYFI
SFYNPERYWEIEFLPLISQSQSELENSVKAFENVISKICQFSHINEGATIGNNESLSD
KFKLPPTSDIEPPNTEIINNDDDNDDDDDNYDDDDLNYLLDEEYEQGCTDNSFSVISN
TCSNLNASFLYPSDPTDAVSISINEAFKNAIRRTAPVLNIPIAAPSIHSKQQNKRYSS
YPFIDSPPYLQDRHRRFQRRSISGLGDL"
gene complement(671887..674766)
/gene="PFK2"
/locus_tag="YMR205C"
/db_xref="GeneID:855245"
mRNA complement(671887..674766)
/gene="PFK2"
/locus_tag="YMR205C"
/product="6-phosphofructokinase subunit beta"
/transcript_id="NM_001182712.1"
/db_xref="GI:296147324"
/db_xref="GeneID:855245"
CDS complement(671887..674766)
/gene="PFK2"
/locus_tag="YMR205C"
/EC_number="2.7.1.11"
/note="Beta subunit of heterooctameric phosphofructokinase
involved in glycolysis, indispensable for anaerobic
growth, activated by fructose-2,6-bisphosphate and AMP,
mutation inhibits glucose induction of cell cycle-related
genes"
/codon_start=1
/product="6-phosphofructokinase subunit beta"
/protein_id="NP_013932.1"
/db_xref="GI:6323861"
/db_xref="SGD:S000004818"
/db_xref="GeneID:855245"
/translation="MTVTTPFVNGTSYCTVTAYSVQSYKAAIDFYTKFLSLENRSSPD
ENSTLLSNDSISLKILLRPDEKINKNVEAHLKELNSITKTQDWRSHATQSLVFNTSDI
LAVKDTLNAMNAPLQGYPTELFPMQLYTLDPLGNVVGVTSTKNAVSTKPTPPPAPEAS
AESGLSSKVHSYTDLAYRMKTTDTYPSLPKPLNRPQKAIAVMTSGGDAPGMNSNVRAI
VRSAIFKGCRAFVVMEGYEGLVRGGPEYIKEFHWEDVRGWSAEGGTNIGTARCMEFKK
REGRLLGAQHLIEAGVDALIVCGGDGSLTGADLFRSEWPSLIEELLKTNRISNEQYER
MKHLNICGTVGSIDNDMSTTDATIGAYSALDRICKAIDYVEATANSHSRAFVVEVMGR
NCGWLALLAGIATSADYIFIPEKPATSSEWQDQMCDIVSKHRSRGKRTTIVVVAEGAI
AADLTPISPSDVHKVLVDRLGLDTRITTLGHVQRGGTAVAYDRILATLQGLEAVNAVL
ESTPDTPSPLIAVNENKIVRKPLMESVKLTKAVAEAIQAKDFKRAMSLRDTEFIEHLN
NFMAINSADHNEPKLPKDKRLKIAIVNVGAPAGGINSAVYSMATYCMSQGHRPYAIYN
GWSGLARHESVRSLNWKDMLGWQSRGGSEIGTNRVTPEEADLGMIAYYFQKYEFDGLI
IVGGFEAFESLHQLERARESYPAFRIPMVLIPATLSNNVPGTEYSLGSDTALNALMEY
CDVVKQSASSTRGRAFVVDCQGGNSGYLATYASLAVGAQVSYVPEEGISLEQLSEDIE
YLAQSFEKAEGRGRFGKLILKSTNASKALSATKLAEVITAEADGRFDAKPAYPGHVQQ
GGLPSPIDRTRATRMAIKAVGFIKDNQAAIAEARAAEENFNADDKTISDTAAVVGVKG
SHVVYNSIRQLYDYETEVSMRMPKVIHWQATRLIADHLVGRKRVD"
gene 675896..676837
/locus_tag="YMR206W"
/db_xref="GeneID:855246"
mRNA 675896..676837
/locus_tag="YMR206W"
/product="hypothetical protein"
/transcript_id="NM_001182713.1"
/db_xref="GI:296147325"
/db_xref="GeneID:855246"
CDS 675896..676837
/locus_tag="YMR206W"
/note="hypothetical protein; YMR206W is not an essential
gene"
/codon_start=1
/product="hypothetical protein"
/protein_id="NP_013933.1"
/db_xref="GI:6323862"
/db_xref="SGD:S000004819"
/db_xref="GeneID:855246"
/translation="MLSSSSNRPISAHLTIHYKAIQEEEGEDMRSGAGSGGHHDDYFL
ESNRSPTPNKKHEFIKTVLNINDNDSEFSESCSPREKLHNEGACNTDLFGDFMSKRQQ
RLSNSMNIYDLYQCVHNLSPSNNNHQFIARRFSDSHIPSLHHRQQQQKVTTKNFVQPT
KDIQRIASYAADSDQRVKYLPNYHQSAPSTALSAAESKAAVPRKLPDRDSTQNYVLKL
QLSSPNSQPMSPRTRPGYRPSCSSSNCSSSSSSSACSSVSISDPNNITAYETNNVNPQ
FPSNQPLDISSPCARHHHRRNSIAVKFDKALYKKTTG"
gene complement(677193..683564)
/gene="HFA1"
/locus_tag="YMR207C"
/db_xref="GeneID:855247"
mRNA complement(677193..683564)
/gene="HFA1"
/locus_tag="YMR207C"
/product="acetyl-CoA carboxylase HFA1"
/transcript_id="NM_001182714.1"
/db_xref="GI:296147326"
/db_xref="GeneID:855247"
CDS complement(677193..683564)
/gene="HFA1"
/locus_tag="YMR207C"
/EC_number="6.4.1.2"
/EC_number="6.3.4.14"
/note="Mitochondrial acetyl-coenzyme A carboxylase;
catalyzes the production of malonyl-CoA in mitochondrial
fatty acid biosynthesis; relocalizes from mitochondrion to
cytoplasm upon DNA replication stress"
/codon_start=1
/product="acetyl-CoA carboxylase HFA1"
/protein_id="NP_013934.1"
/db_xref="GI:6323863"
/db_xref="SGD:S000004820"
/db_xref="GeneID:855247"
/translation="MRSIRKWAYETFNDEKIIQFVVMATPDDLHANSEYIRMADQYVQ
VPGGTNNNNYANIDLILDVAEQTDVDAVWAGWGHASENPCLPELLASSQRKILFIGPP
GRAMRSLGDKISSTIVAQSAKIPCIPWSGSHIDTIHIDNKTNFVSVPDDVYVRGCCSS
PEDALEKAKLIGFPVMIKASEGGGGKGIRRVDNEDDFIALYRQAVNETPGSPMFVMKV
VTDARHLEVQLLADQYGTNITLFGRDCSIQRRHQKIIEEAPVTITKPETFQRMERAAI
RLGELVGYVSAGTVEYLYSPKDDKFYFLELNPRLQVEHPTTEMISGVNLPATQLQIAM
GIPMHMISDIRKLYGLDPTGTSYIDFKNLKRPSPKGHCISCRITSEDPNEGFKPSTGK
IHELNFRSSSNVWGYFSVGNNGAIHSFSDSQFGHIFAVGNDRQDAKQNMVLALKDFSI
RGEFKTPIEYLIELLETRDFESNNISTGWLDDLILKNLSSDSKLDPTLAIICGAAMKA
YVFTEKVRNKYLELLRRGQVPPKDFLKTKFPVDFIFDNNRYLFNVAQSSEEQFILSIN
KSQCEVNVQKLSSDCLLISVDGKCHTVYWKDDIRGTRLSIDSNTIFLEAELNPTQVIS
PTPGKLVKYLVRSGDHVFAGQQYAEIEIMKMQMPLVAKSDGVIELLRQPGSIIEAGDV
IAKLTLDSPSKANESSLYRGELPVLGPPLIEGSRPNHKLRVLINRLENILNGYHENSG
IETTLKELIKILRDGRLPYSEWDSQISTVRNRLPRQLNEGLGNLVKKSVSFPAKELHK
LMKRYLEENTNDHVVYVALQPLLKISERYSEGLANHECEIFLKLIKKYYAVEKIFENH
DIHEERNLLNLRRKDLTNLKKILCISLSHANVVAKNKLVTAILHEYEPLCQDSSKMSL
KFRAVIHDLASLESKWAKEVAVKARSVLLRGIFPPIKKRKEHIKTLLQLHIKDTGAEN
IHSRNIYSCMRDFGNLIHSNLIQLQDLFFFFGHQDTALSSIASEIYARYAYGNYQLKS
IKIHKGAPDLLMSWQFSSLRNYLVNSDGESDEFTKLSKPPSTSGKSSANSFGLLVNMR
ALESLEKTLDEVYEQIHIPEERLSSGENSLIVNILSPIRYRSENDLIKTLKIKLHENE
RGLSKLKVNRITFAFIAANAPAVKFYSFDGTTYDEISQIRNMDPSYEAPLELGKMSNY
KIRSLPTYDSSIRIFEGISKFTPLDKRFFVRKIINSFMYNDQKTTEENLKAEINAQVV
YMLEHLGAVDISNSDLNHIFLSFNTVLNIPVHRLEEIVSTILKTHETRLFQERITDVE
ICISVECLETKKPAPLRLLISNKSGYVVKIETYYEKIGKNGNLILEPCSEQSHYSQKS
LSLPYSVKDWLQPKRYKAQFMGTTYVYDFPGLFHQAAIQQWKRYFPKHKLNDSFFSWV
ELIEQNGNLIKVNREPGLNNIGMVAFEIMVQTPEYPEGRNMIVISNDITYNIGSFGPR
EDLFFDRVTNYARERGIPRIYLAANSGAKLGIAEELIPLFRVAWNDPSDPTKGFQYLY
LAPKDMQLLKDSGKGNSVVVEHKMVYGEERYIIKAIVGFEEGLGVECLQGSGLIAGAT
SKAYRDIFTITAVTCRSVGIGSYLVRLGQRTIQVEDKPIILTGASAINKVLGTDIYTS
NLQIGGTQIMYKNGIAHLTASNDMKAIEKIMTWLSYVPAKRDMSPPLLETMDRWDRDV
DFKPAKQVPYEARWLIEGKWDSNNNFQSGLFDKDSFFETLSGWAKGVIVGRARLGGIP
VGVIAVETKTIEEIIPADPANLDSSEFSVKEAGQVWYPNSAFKTAQTINDFNYGEQLP
LIILANWRGFSGGQRDMYNEVLKYGSFIVDALVDYKQPILIYIPPFGELRGGSWVVID
PTINPEQMEMYADVESRGGVLEPDGVVSIKYRKEKMIETMIRLDSTYGHLRRTLTEKK
LSLEKQNDLTKRLKIRERQLIPIYNQISIQFADLHDRSTRMLVKGVIRNELEWKKSRR
FLYWRLRRRLNEGQVIKRLQKKTCDNKTKMKYDDLLKIVQSWYNDLDVNDDRAVVEFI
ERNSKKIDKNIEEFEISLLIDELKKKFEDRRGNIVLEELTRLVDSKRKR"
gene 684467..685798
/gene="ERG12"
/locus_tag="YMR208W"
/gene_synonym="RAR1"
/db_xref="GeneID:855248"
mRNA 684467..685798
/gene="ERG12"
/locus_tag="YMR208W"
/gene_synonym="RAR1"
/product="mevalonate kinase"
/transcript_id="NM_001182715.1"
/db_xref="GI:296147327"
/db_xref="GeneID:855248"
CDS 684467..685798
/gene="ERG12"
/locus_tag="YMR208W"
/gene_synonym="RAR1"
/EC_number="2.7.1.36"
/note="Mevalonate kinase, acts in the biosynthesis of
isoprenoids and sterols, including ergosterol, from
mevalonate"
/codon_start=1
/product="mevalonate kinase"
/protein_id="NP_013935.1"
/db_xref="GI:6323864"
/db_xref="SGD:S000004821"
/db_xref="GeneID:855248"
/translation="MSLPFLTSAPGKVIIFGEHSAVYNKPAVAASVSALRTYLLISES
SAPDTIELDFPDISFNHKWSINDFNAITEDQVNSQKLAKAQQATDGLSQELVSLLDPL
LAQLSESFHYHAAFCFLYMFVCLCPHAKNIKFSLKSTLPIGAGLGSSASISVSLALAM
AYLGGLIGSNDLEKLSENDKHIVNQWAFIGEKCIHGTPSGIDNAVATYGNALLFEKDS
HNGTINTNNFKFLDDFPAIPMILTYTRIPRSTKDLVARVRVLVTEKFPEVMKPILDAM
GECALQGLEIMTKLSKCKGTDDEAVETNNELYEQLLELIRINHGLLVSIGVSHPGLEL
IKNLSDDLRIGSTKLTGAGGGGCSLTLLRRDITQEQIDSFKKKLQDDFSYETFETDLG
GTGCCLLSAKNLNKDLKIKSLVFQLFENKTTTKQQIDDLLLPGNTNLPWTS"
gene complement(685911..687284)
/locus_tag="YMR209C"
/db_xref="GeneID:855249"
mRNA complement(685911..687284)
/locus_tag="YMR209C"
/product="hypothetical protein"
/transcript_id="NM_001182716.1"
/db_xref="GI:296147328"
/db_xref="GeneID:855249"
CDS complement(685911..687284)
/locus_tag="YMR209C"
/note="Putative S-adenosylmethionine-dependent
methyltransferase; YMR209C is not an essential gene"
/codon_start=1
/product="hypothetical protein"
/protein_id="NP_013936.1"
/db_xref="GI:6323865"
/db_xref="SGD:S000004822"
/db_xref="GeneID:855249"
/translation="MVSSLASNIILALVVVLMTLLRQNKPLQRWFVSYVEKLLSRKSN
LAQKVSVLSPSLKLVDVEKSISADQSNLSKINYQIPTLPDLTGNLIRLHEYRARGEGY
NGLLFRRARQLNGISEDQLQKLGYFTKLMKNNEGIRENARVIDKIIEFTLGKLIHSNE
HDEEFTEEIEKICAEHGYKIKDGHLIQLNPDFVFPIVSSRGSQSVVHEALAHLCRDFS
SYYSVERDPLQNFIISRINHHVISAGDMKEKILIVTPGAGVGGLSHTLATTFPKIQVD
SIELSALMYICNLFALEYKHDVKIRPFVQQYSCQTVFDNQLRSLSADLSKVGHRSNLD
PLWGDFTRYSPISKDYDKIIICSAYFIDTAENMFEYLSSIEALKKYCKELHWVNVGPL
KYGTKPLVQFTGDELSRLRKIRGWKDLVEEYEVDSSKGLNGYLTDYESMYQGYYGLLK
FHSVFES"
gene 687516..688865
/locus_tag="YMR210W"
/db_xref="GeneID:855250"
mRNA 687516..688865
/locus_tag="YMR210W"
/product="putative carboxylic ester hydrolase"
/transcript_id="NM_001182717.1"
/db_xref="GI:296147329"
/db_xref="GeneID:855250"
CDS 687516..688865
/locus_tag="YMR210W"
/EC_number="3.1.1.-"
/note="Putative acyltransferase with similarity to Eeb1p
and Eht1p, has a minor role in medium-chain fatty acid
ethyl ester biosynthesis; may be involved in lipid
metabolism and detoxification"
/codon_start=1
/product="putative carboxylic ester hydrolase"
/protein_id="NP_013937.1"
/db_xref="GI:6323866"
/db_xref="SGD:S000004823"
/db_xref="GeneID:855250"
/translation="MRLKELLPNFLIVHQEVPEDPIAFKSTDKRENENKEITIPELID
TKVPELADGATDTLYGLLVNGHLQTAYGSFRHFDNIYKVQYKRMIIKYPHGGEGTVDF
AVNGRSTKRRKVEKEYVPTSQPVFNGNLKRRYSYYSPDDPKLNSDDAKPMLIILHGLT
GGSRESYVRAIVHEITTKYDFEACVFNARGCCYSAITTPLLYNGGWTNDIRYCVNDLR
KRFPNRKFYMMGFSLGASIMTNYLGEESDRTKIECAISVSNPFDLYNSAYFINSTPMG
SRFYSPALGHNLLRMVRNHLSTLEENPDFKDVIEKHLKKIRTVRQFDNLLTGPMFGYK
NAEEYYKNASSYKRIPGIRTPFIALHAQDDPIVGGDLPIDQIKSNPYTLLLETSTGGH
VGWFKDRSGRRWYAEPLCRFLKIFHDEITVKGLKPDLENVQLPDPNCEPIATTFRAN"
gene 689083..690510
/gene="DML1"
/locus_tag="YMR211W"
/db_xref="GeneID:855251"
mRNA 689083..690510
/gene="DML1"
/locus_tag="YMR211W"
/product="Dml1p"
/transcript_id="NM_001182718.1"
/db_xref="GI:296147330"
/db_xref="GeneID:855251"
CDS 689083..690510
/gene="DML1"
/locus_tag="YMR211W"
/note="Essential protein involved in mtDNA inheritance,
may also function in the partitioning of the mitochondrial
organelle or in the segregation of chromosomes, exhibits
regions similar to members of a GTPase family"
/codon_start=1
/product="Dml1p"
/protein_id="NP_013938.1"
/db_xref="GI:6323867"
/db_xref="SGD:S000004824"
/db_xref="GeneID:855251"
/translation="MHEVVTISVSQRANHLTTQFFNIQEGYLQLSKEQQVNDSKIFLN
SVVDKVSKTISYAPRALLWDARTGNGSLGTYQYSESQDYHFGNEDKFKEQTVIKTHPR
IPKSEYQSSLDAGAPLPCLNRENTMYWSDYSKLIYGPSSFNILRNWYHDTENPNQPDF
QNLGERKFDRYSIGYDEFTENYLQEFFDGNLHRELEKCDTLQGFNLVSDMESGWGGFS
SALLVELRNELPKKAVFSWGHNEDDPFTDDFPMKRLSKKWLPIISNKLRSTINMMQES
DLYFPLYAAPGLTNWETAGKSCRIFDSINATISQSNLEQRKTMDYLTTAITLGYSSRN
MVTGMVIGDTDYSFCSRVLPFKNSHKPNSTHIFSKSFIDRGNQTHKHHSEPDSRSKMI
EMYTHRYFPSDTIPTEFSNDREFVLELESSEKNRDIFKHWNEFVVRYFKNDSDREELK
NELSDYASAYESGWYEDEDSGDDDM"
gene complement(690695..693043)
/gene="EFR3"
/locus_tag="YMR212C"
/db_xref="GeneID:855252"
mRNA complement(690695..693043)
/gene="EFR3"
/locus_tag="YMR212C"
/product="Efr3p"
/transcript_id="NM_001182719.1"
/db_xref="GI:296147331"
/db_xref="GeneID:855252"
CDS complement(690695..693043)
/gene="EFR3"
/locus_tag="YMR212C"
/note="Protein required for Stt4-containing
phosphoinositide kinase patch assembly at the plasma
membrane; exhibits synthetic lethal genetic interactions
with PHO85; has sequence similarity to the Drosophila
rolling blackout (RBO) gene"
/codon_start=1
/product="Efr3p"
/protein_id="NP_013939.1"
/db_xref="GI:6323868"
/db_xref="SGD:S000004825"
/db_xref="GeneID:855252"
/translation="MQLSMRMMFTPKHQKLVNQCYPTGRTTDKKPKSSETSYLLYYVN
SRRSKLEKVSTYLIKRSTSDLNHRRIGNIAVTLDLMNKIVLHCKENLNVFVKDFLYIM
NKVLSNNNFNNDVSVVELIELAFSSICQNLDDVLCNGDMEFVQLYQNFVDLFFKIVTE
RIHNDDMLLKCCIDISNTNSVSSNPQLNHFVSKSVAYTISKFQERNPKFKTLSLEAAL
ESNLGKRLSRTQTRTIGLDKAAEDNHDLSVKALQSYFNTTETDKLNLSIRTLLRCLQS
TPNKELLEFVCNGIPVQLRYIVILLLVRQLSDKDKNVNPIVSLKLMSSLLVSDVSIVG
LSVLDIMRKLLNFQLKNATNKEVVAQSCITMTDLNHKTYYAEQTSDMLYELLLKLKSD
TVKDVEKNAVVEDIDFLVEHITQPSISLELFIDLAHYMKNHIICLFNIVETEVPSSIL
FSKLYSLLRELDSHGVQKEMMEEIFDKYGKMALLSGLNYFLENVSEPEYTYYSYHLQA
ANFLKLNDYKSQTEYKMQTRTLFTKEDLLSYYSDTGSNKYSKKGAQILLSRDNQISTS
DLLSDSQVRTTPLEYKNVPNAIFSNGKAVYDNNDFAAKQNKFDNSIDDNIEEANDTVI
SDANAKGSIYRFVAEDARSWKTMRATAPKVSDLKKTMNEKNIPNNMKRDGSFRGSQSV
KSRVTNITFLLNELKTFSDDANKIKDPDEENIVGLDKIDVARSNSLRLAPISSLSDRS
SIGNRKSFLQKTATGENQNDDFKDANEDLHSLSSRGKIFSST"
gene 693381..695153
/gene="CEF1"
/locus_tag="YMR213W"
/gene_synonym="NTC85"
/db_xref="GeneID:855253"
mRNA 693381..695153
/gene="CEF1"
/locus_tag="YMR213W"
/gene_synonym="NTC85"
/product="Cef1p"
/transcript_id="NM_001182720.1"
/db_xref="GI:296147332"
/db_xref="GeneID:855253"
CDS 693381..695153
/gene="CEF1"
/locus_tag="YMR213W"
/gene_synonym="NTC85"
/note="Essential splicing factor; associated with Prp19p
and the spliceosome, contains an N-terminal c-Myb DNA
binding motif necessary for cell viability but not for
Prp19p association, evolutionarily conserved and
homologous to S. pombe Cdc5p"
/codon_start=1
/product="Cef1p"
/protein_id="NP_013940.1"
/db_xref="GI:6323869"
/db_xref="SGD:S000004826"
/db_xref="GeneID:855253"
/translation="MPPVPIYVKGGVWTNVEDQILKAAVQKYGTHQWSKVASLLQKKT
ARQSELRWNEYLNPKLNFTEFSKEEDAQLLDLARELPNQWRTIADMMARPAQVCVERY
NRLLESEDSGGAALSTGVTDLKAGDINPNAETQMARPDNGDLEDEEKEMLAEARARLL
NTQGKKATRKIRERMLEESKRIAELQKRRELKQAGINVAIKKPKKKYGTDIDYNEDIV
YEQAPMPGIYDTSTEDRQIKKKFEQFERKVNRKGLDGNKDKPSKKNKDKKRKHDENEH
VEKAALGESTTLTDEYKKPKLILSAPGTKQGKVTYKKKLESKRQKLIEAQATGTVLTP
KELLPHDSGQEDNERSNIKSGKQLKSRIRKFLVQMFASLPSPKNDFEIVLSEDEKEED
AEIAEYEKEFENERAMNEEDNFIEPPSQNDAPRVSLVAVPLAYSTLPIPEFKNNPQSA
IDNKYNLLVANAINKEPHMVPEDTVDFLKEVESRMQHITQGRTSMKIQFKTAMPPTEV
LLESIQSKVESIEQLQRKLQHVQPLEQQNNEMCSTLCHHSLPALIEGQRKYYADYYAY
RQEIRSLEGRRKRLQAMLNSSSSI"
gene 695350..696483
/gene="SCJ1"
/locus_tag="YMR214W"
/db_xref="GeneID:855254"
mRNA 695350..696483
/gene="SCJ1"
/locus_tag="YMR214W"
/product="Scj1p"
/transcript_id="NM_001182721.1"
/db_xref="GI:296147333"
/db_xref="GeneID:855254"
CDS 695350..696483
/gene="SCJ1"
/locus_tag="YMR214W"
/note="One of several homologs of bacterial chaperone
DnaJ, located in the ER lumen where it cooperates with
Kar2p to mediate maturation of proteins"
/codon_start=1
/product="Scj1p"
/protein_id="NP_013941.2"
/db_xref="GI:37362683"
/db_xref="SGD:S000004827"
/db_xref="GeneID:855254"
/translation="MIPKLYIHLILSLLLLPLILAQDYYAILEIDKDATEKEIKSAYR
QLSKKYHPDKNAGSEEAHQKFIEVGEAYDVLSDPEKKKIYDQFGADAVKNGGGGGGPG
GPGAGGFHDPFDIFERMFQGGHGGPGGGFGQRQRQRGPMIKVQEKLSLKQFYSGSSIE
FTLNLNDECDACHGSGSADGKLAQCPDCQGRGVIIQVLRMGIMTQQIQQMCGRCGGTG
QIIKNECKTCHGKKVTKKNKFFHVDVPPGAPRNYMDTRVGEAEKGPDFDAGDLVIEFK
EKDTENMGYRRRGDNLYRTEVLSAAEALYGGWQRTIEFLDENKPVKLSRPAHVVVSNG
EVEVVKGFGMPKGSKGYGDLYIDYVVVMPKTFKSGQNMLKDEL"
gene 696796..698370
/gene="GAS3"
/locus_tag="YMR215W"
/db_xref="GeneID:855255"
mRNA 696796..698370
/gene="GAS3"
/locus_tag="YMR215W"
/product="Gas3p"
/transcript_id="NM_001182722.1"
/db_xref="GI:296147334"
/db_xref="GeneID:855255"
CDS 696796..698370
/gene="GAS3"
/locus_tag="YMR215W"
/note="Low abundance, possibly inactive member of the GAS
family of GPI-containing proteins; putative
1,3-beta-glucanosyltransferase with similarity to other
GAS family members; localizes to the cell wall; mRNA
induced during sporulation"
/codon_start=1
/product="Gas3p"
/protein_id="NP_013942.1"
/db_xref="GI:6323871"
/db_xref="SGD:S000004828"
/db_xref="GeneID:855255"
/translation="MQLSKSILLAALAATPSLVNAMLPIHIKNYRFIKPSSATNSESD
NEVFFVKGVDYQPGGSSGYDADSDTDILSDPEVCARDAYAFQQLGVNTVRIYSLNPDL
NHDKCMTIFNNAGIYAILDVNSGNYGESLNRADPSGTYDSLYLSRVFKFIDAFKNYPN
VLGFFSGNEVINDQSDYAKIDPPYIRAVQRDMKQYISKHANRSIPVGYSAADNTDLRL
ATFKYLQCNSLDGNKVNDDLDISKSDFFGLNTYEWCSGTSSWESSGYDKLNSTFEDAV
IPLIFSEYGCNKNTPRTFDEVSEGLYGGLKNVFSGGLVYEYTEEANNYGLVKLDDSGS
LTYKDDFVNLESQLKNVSLPTTKESEISSDSIYKCDNSAITNIYSGFGTNNFTLPSQP
AEIANMIEYGVNGTNTGKILTDYAVPTTFNYTIKNNKDDTISATISYDKANSLNELDV
TATTVAKSASTSQSSSRSLTSSTSPSSSTGSSSSTGSSSASSSSKSKGVGNIVNVSFS
QSGYLALFAGLISALL"
gene complement(698811..701039)
/gene="SKY1"
/locus_tag="YMR216C"
/db_xref="GeneID:855256"
mRNA complement(698811..701039)
/gene="SKY1"
/locus_tag="YMR216C"
/product="Sky1p"
/transcript_id="NM_001182723.1"
/db_xref="GI:296147335"
/db_xref="GeneID:855256"
CDS complement(698811..701039)
/gene="SKY1"
/locus_tag="YMR216C"
/EC_number="2.7.11.1"
/note="SR protein kinase (SRPK) involved in regulating
proteins involved in mRNA metabolism and cation
homeostasis; similar to human SRPK1"
/codon_start=1
/product="Sky1p"
/protein_id="NP_013943.1"
/db_xref="GI:6323872"
/db_xref="SGD:S000004829"
/db_xref="GeneID:855256"
/translation="MGSSINYPGFVTKSAHLADTSTDASISCEEATSSQEAKKNFFQR
DYNMMKKAPAPTKSKLSLALQTSKSSSSANGTVQEDTSSKTEDFSTKSIKKKPDSGVE
SHVSIQSDSGPQSDSDLDSDSSISSCDERNEESLKDYRPGGYHPAFKGEPYKDARYIL
VRKLGWGHFSTVWLAKDMVNNTHVAMKIVRGDKVYTEAAEDEIKLLQRVNDADNTKED
SMGANHILKLLDHFNHKGPNGVHVVMVFEVLGENLLALIKKYEHRGIPLIYVKQISKQ
LLLGLDYMHRRCGIIHTDIKPENVLMEIGDVEGIVQMVEALDKQKREAKRLQRHVSRS
SDITANDSSDEKWAECQTSMPCGSSSNSKSRSIEKDLSKRCFRRPRRHTIITGSQPLP
SPISSSNFFEMRAHFCGSSHNSFSSVSGNRNIPSSINNNSINNGIGIKNSNNSFLNSV
PHSVTRMFINEDSNDNNNNDNSKNKNNNNNNSNNNNNEDIMNTPLHEEQLADSLSTFD
ISNISQSSDTNGPYISNTMDSNSNVSTDINSPENLIQIKIADLGNACWYDEHYTNSIQ
TREYRSPEVLLGAPWGCGADIWSTACLIFELITGDFLFEPDEGHSYTKDDDHIAQIIE
LLGELPSYLLRNGKYTRTFFNSRGLLRNISKLKFWPLEDVLTEKYKFSKDEAKEISDF
LSPMLQLDPRKRADAGGLVNHPWLKDTLGMEEIRVPDRELYGSGSDIPGWFEEVRDHK
RH"
gene 701790..703367
/gene="GUA1"
/locus_tag="YMR217W"
/db_xref="GeneID:855257"
mRNA 701790..703367
/gene="GUA1"
/locus_tag="YMR217W"
/product="GMP synthase (glutamine-hydrolyzing)"
/transcript_id="NM_001182724.1"
/db_xref="GI:296147336"
/db_xref="GeneID:855257"
CDS 701790..703367
/gene="GUA1"
/locus_tag="YMR217W"
/EC_number="6.3.5.2"
/note="GMP synthase; highly conserved enzyme that
catalyzes the second step in the biosynthesis of GMP from
inosine 5'-phosphate (IMP); transcription is not subject
to regulation by guanine but is negatively regulated by
nutrient starvation; reduction-of-function mutation
gua1-G388D causes changes in cellular guanine nucleotide
pools, defects in general protein synthesis, and impaired
translation of GCN4 mRNA"
/codon_start=1
/product="GMP synthase (glutamine-hydrolyzing)"
/protein_id="NP_013944.1"
/db_xref="GI:6323873"
/db_xref="SGD:S000004830"
/db_xref="GeneID:855257"
/translation="MAAGEQVSNMFDTILVLDFGSQYSHLITRRLREFNIYAEMLPCT
QKISELGWTPKGVILSGGPYSVYAEDAPHVDHAIFDLNVPILGICYGMQELAWINGKQ
VGRGDKREYGPATLKVIDDSNSLFKGMNDSTVWMSHGDKLHGLPTGYKTIATSDNSPY
CGIVHETKPIYGIQFHPEVTHSTQGKTLLKNFAVDLCHAKQNWTMENFIDTEINRIRK
LVGPTAEVIGAVSGGVDSTVASKLMTEAIGDRFHAILVDNGVLRLNEAANVKKTLVEG
LGINLMVVDASEEFLSKLKGVTDPEKKRKIIGNTFIHVFEREAEKIKPKDGKEIQFLL
QGTLYPDVIESISFKGPSQTIKTHHNVGGLLENMKLKLIEPLRELFKDEVRHLGELLG
IPHDLVWRHPFPGPGIAIRVLGEVTKEQVEIARKADNIYIEEIKKAGLYNQISQAFAC
LLPVKSVGVMGDQRTYDQVIALRAIETTDFMTADWFPFEHSFLKKVASRIVNEVDGVA
RVTYDITSKPPATVEWE"
gene complement(703579..706887)
/gene="TRS130"
/locus_tag="YMR218C"
/db_xref="GeneID:855258"
mRNA complement(703579..706887)
/gene="TRS130"
/locus_tag="YMR218C"
/product="Trs130p"
/transcript_id="NM_001182725.1"
/db_xref="GI:296147337"
/db_xref="GeneID:855258"
CDS complement(703579..706887)
/gene="TRS130"
/locus_tag="YMR218C"
/note="One of 10 subunits of the transport protein
particle (TRAPP) complex of the cis-Golgi which mediates
vesicle docking and fusion; involved in ER to Golgi
membrane traffic; mutation activates transcription of
OCH1; mutants are defective in cytoplasm-to-vacuole
targeting (Cvt) pathway and starvation-induced autophagy"
/codon_start=1
/product="Trs130p"
/protein_id="NP_013945.1"
/db_xref="GI:6323874"
/db_xref="SGD:S000004831"
/db_xref="GeneID:855258"
/translation="MDKEIYCGSVPVSYFDPFDLFESLRPEFQQILPLDNIHWKAFDG
TVRTVNRLPIELIPEGRGEADKSNDEQPFIRFLIVNCISIDQYRAKVRPLVRQWLPNL
ESVSSSTGEKMIYKPIILLYANSEVVDSNLFKSVSLMEKFGKDFPHVQTLEVRSVYRS
PKERQEFWNQFSQKIKASVLSIFQKRLTHLQHSLANLQKGNNFEEQLLTREKLYELYV
VFNILEDASLELQKIKKEILRRNMNMPDGKLQVPFESSSKSDESLGSIIIEGTLDKFQ
LHKYFFIRRLRLLKLEDQTLTAFVGAFQLIKNFIESISIEYRKSVRLLEFKHYFITSM
LSYFEFENVSNPLLCEIKAELLMLKRDNWVQGVMATSGYRLMDKNYPNSDVKYKFDLL
KETFVDETVFQENFLTLTKEILSLFNKCEGKRQRIVDILSIEIGLLYYQGKKYEEAVS
LFLSCYEYYTQTNWNSIGLKILQVFIDSLSHCPKLDVLQIDGESVSASAVLTNAFLNI
LKLCKDNDSKEIWWKKFMDLQMKNNIHLMYPLDGLFEVTLNSKVHLARANVSAIEVNL
KSYGFPEDISTKTMRLSLKNMGGDVIVFGASDFLLKKGENKLILECRDIMYGEFSLLS
FEIIVEGITFVKEFPENQDEFIVVPEIYCKESTKVLVKQAHNLNLGEYALELKSVQSD
ALESLQVEVEVQKNIGNMKNLPVSFSMDEIQARKRYNTPFENVRLEYYLLDQITAFDL
IIKTSFTKKNDQGTFGETKKVRIQCYLQLSVSVEDIFKKDIFFFKFLLNSSVREEPVI
LYSSELSAPDTRNDYNIRGDYIATTPALITFDGNESFINCYEITANNNFDSKDIFNLK
VRYNTLKEQLDCFITDAVLIEGDVEWFILFEKWKTFWELEILKKLKYDYDAFKENRII
RLLKTSIDLNKTKSKIRNLCIEKAVLDKILICLNKVSRGIAVCNTDMDEYVRNLVPKQ
LTVPVQLPGFEQFFHVQFEQMETSHDALHDTIATIGNSLSYTVIVENLSGQWGQDVID
DGGYIFEILSSNEWLIHGQKRCAIKEKRKEFEVHLIPLKKGYLNFPRVEITNINGKSC
RVDHSNAFESILIF"
gene 707133..712109
/gene="ESC1"
/locus_tag="YMR219W"
/db_xref="GeneID:855259"
mRNA 707133..712109
/gene="ESC1"
/locus_tag="YMR219W"
/product="Esc1p"
/transcript_id="NM_001182726.1"
/db_xref="GI:296147338"
/db_xref="GeneID:855259"
CDS 707133..712109
/gene="ESC1"
/locus_tag="YMR219W"
/note="Protein localized to the nuclear periphery,
involved in telomeric silencing; interacts with
PAD4-domain of Sir4p"
/codon_start=1
/product="Esc1p"
/protein_id="NP_013946.1"
/db_xref="GI:6323875"
/db_xref="SGD:S000004832"
/db_xref="GeneID:855259"
/translation="MSKKKETFTPRANKLKLTTPRRKLKILSSLLDADEDSKMKDQHG
YSRVHNDKYRVAKPTQHSTLHESISSRRSSHIHNKSLHEDSARALSWVDSLINRGKSI
LTTLEKEDALFERSLEEERQRFQLHDSLMNKYTGNSKSHQRLIDLRKSQYGTDTSFQN
NDEIPLDSFISSPLPDAEDESSSNIDSDKDEDLEGKQSLIKDFDLENDEYELSEEEKN
SDGQSSPSIMILSDEEYAEEGALQDVSNDEYAEEEGQVERKNIGQEQANVENATQISS
SDSSEGQNYSEGVEMELEDDIDVESDAEKDESQGAEGTEHSVDFSKYMQPRTDNTKIP
VIEKYESDEHKVHQRYSEDGAFDFGSVNISVDDESEDEESQAESYSANAENVYHHNEH
ELDDKELIEDIESSDSESQSAQESEQGSEDDFEYKMKNEKSTSEETENTSESRDQGFA
KDAYTKNKVEQQENDEEPEKDDIIRSSLDKNFHGNNNKSEYSENVLENETDPAIVERE
NQINDVEGYDVTGKSVESDLHEHSPDNLYDLAARAMLQFQQSRNSNCPQKEEQVSESY
LGHSNGSNLSGRSLDESEEQIPLKDFTGENNNNLKTDRGDLSSSVEIEVEKVSEKKLD
GSTEKELVPLSTDTTINNSSLGNEDSIYYSLDDADAISENLTDVPLMEIKTTPKYEVV
ISESVYSSTSYEDNTVAMPPQVEYTSPFMNDPFNSLNDDYEKKHDLLKSTLAALAPAF
TKKDAEFVEAGVTKSCLTSTSGHTNIFHTSKETKQVSDLDESTENVTFENENTGDENK
NQSKNFPGVANSTDKSTEDNTDEKYFSAINYTNVTGDSSCEDIIETASNVEENLRYCE
KDMNEAEMSSGDECVKQNDDGSKTQISFSTDSPDNFQESNDNTEFSSTKYKVRNSDLE
DDESLKKELTKAEVVDKLDEEESEDSYEQDYADPEPGNDEGSNENIVKGTKKDTLGIV
EPENEKVNKVHEEETLFEANVSSSVNVQNKDMHTDVINQEAQANYEAGERKYYIQNTD
TEEAHISIIERIDENAIGNNMEIPERSCVEKTHNEVLFERRATTIENTKALENNTNMH
DQVSQACSDSDRDQDSTAEKNVEGSAKHNLDIRVSSSEIESVEPLKPESDRSNIFSSP
IRVIGAVVKGVGKVVDVAESFVKKIDVMDSESDDNVDIGDYNQDIFNKSNSTDASVNM
KSVSSKERDSDEDEAVILGGVTAEAHNDNGNNSRVINIDPTTNGAYEEDSEVFRQQVK
DKENLHKSEEPLVEGLQSEQHFEKKDHSENEEEFDTIYGDITSANIHSNAPDDIKRQQ
LLKNLSDLENYSQRLIEDSRRGKNQEESDEVNTSRERDLTFEKSVNEKYAGAIEEDTF
SELDISIQHPEHEEDLDLSNNQERSIEELNSEPEEAELYELEIEGPTETAASSKMNDD
ERQRGNIPSTDLPSDPPSDKEEVTDSYPYSNSENITAEKSAPTSPEVYEIFSDTPNEV
PMEINDEIPATTLEKHDKTNVTSVLDDRSEHLSSHDVDNEPHDNSINIKVNEGEEPEH
QAVDIPVKVEVKEEQEEMPSKSVLEEQKPSMELINDKSSPENNNDEETNREKDKTKAK
KKSRKRNYNSRRRKRKITEGSSAASNTKRRRGHEPKSRGQNTHPSVDK"
gene 712316..713671
/gene="ERG8"
/locus_tag="YMR220W"
/db_xref="GeneID:855260"
mRNA 712316..713671
/gene="ERG8"
/locus_tag="YMR220W"
/product="phosphomevalonate kinase"
/transcript_id="NM_001182727.1"
/db_xref="GI:296147339"
/db_xref="GeneID:855260"
CDS 712316..713671
/gene="ERG8"
/locus_tag="YMR220W"
/EC_number="2.7.4.2"
/note="Phosphomevalonate kinase, an essential cytosolic
enzyme that acts in the biosynthesis of isoprenoids and
sterols, including ergosterol, from mevalonate"
/codon_start=1
/product="phosphomevalonate kinase"
/protein_id="NP_013947.1"
/db_xref="GI:6323876"
/db_xref="SGD:S000004833"
/db_xref="GeneID:855260"
/translation="MSELRAFSAPGKALLAGGYLVLDTKYEAFVVGLSARMHAVAHPY
GSLQGSDKFEVRVKSKQFKDGEWLYHISPKSGFIPVSIGGSKNPFIEKVIANVFSYFK
PNMDDYCNRNLFVIDIFSDDAYHSQEDSVTEHRGNRRLSFHSHRIEEVPKTGLGSSAG
LVTVLTTALASFFVSDLENNVDKYREVIHNLAQVAHCQAQGKIGSGFDVAAAAYGSIR
YRRFPPALISNLPDIGSATYGSKLAHLVDEEDWNITIKSNHLPSGLTLWMGDIKNGSE
TVKLVQKVKNWYDSHMPESLKIYTELDHANSRFMDGLSKLDRLHETHDDYSDQIFESL
ERNDCTCQKYPEITEVRDAVATIRRSFRKITKESGADIEPPVQTSLLDDCQTLKGVLT
CLIPGAGGYDAIAVITKQDVDLRAQTANDKRFSKVQWLDVTQADWGVRKEKDPETYLD
K"
gene complement(713931..715445)
/locus_tag="YMR221C"
/db_xref="GeneID:855261"
mRNA complement(713931..715445)
/locus_tag="YMR221C"
/product="hypothetical protein"
/transcript_id="NM_001182728.1"
/db_xref="GI:296147340"
/db_xref="GeneID:855261"
CDS complement(713931..715445)
/locus_tag="YMR221C"
/note="hypothetical protein; the authentic, non-tagged
protein is detected in highly purified mitochondria in
high-throughput studies; physical interaction with Atg27p
suggests a possible role in autophagy"
/codon_start=1
/product="hypothetical protein"
/protein_id="NP_013948.1"
/db_xref="GI:6323877"
/db_xref="SGD:S000004834"
/db_xref="GeneID:855261"
/translation="MTSTRTLRYAQVACACIWCLFSAGIIFGFAALKPILISEGVYHE
LCDPKDGDRLLCTAQDLKLNFIFALSATVTNIMALPVGKILDMYGPRVCGIIGSCLLF
LASGNFISAKHLVSLWDPYLVGYTLLAVAGPFVFISCFQLANSFPQRSGTVLALLTGS
FDSSSALFLLYRLLYQNWFPTLNVSRFFTLYLIVPVFILACQLTIMPHSSYKTVNHIA
KIAVEGLDENGRLIEGDTGSGIIPDEQERQSLIAIEREEDSIPSRPQRRKSVLETYVE
DKLQKKSGGIFGVLHGKSAYEQIKSPWFYLMLLFALVAMLRINYFIATVRTQEEYLLN
DPDLALKLNSIFDMLLPLGGAVSIPFIGLLLDHTDTLSTLTILFTTSTAIGVFGLIPN
SFTWNLIGIVLLVVYRPFYYTVVSDYSSKVFGFDTFGTVYGLLSCICGIFNMSQNLLD
KWTHTTFNMNPFPINLTLVILTVVFSLTLTFYIRSQILPKPVNERGLSSNYQTI"
gene complement(715638..716309)
/gene="FSH2"
/locus_tag="YMR222C"
/db_xref="GeneID:855262"
mRNA complement(715638..716309)
/gene="FSH2"
/locus_tag="YMR222C"
/product="Fsh2p"
/transcript_id="NM_001182729.1"
/db_xref="GI:296147341"
/db_xref="GeneID:855262"
CDS complement(715638..716309)
/gene="FSH2"
/locus_tag="YMR222C"
/EC_number="3.1.-.-"
/note="Putative serine hydrolase that localizes to the
cytoplasm; sequence is similar to S. cerevisiae Fsh1p and
Fsh3p and the human candidate tumor suppressor OVCA2"
/codon_start=1
/product="Fsh2p"
/protein_id="NP_013949.1"
/db_xref="GI:6323878"
/db_xref="SGD:S000004835"
/db_xref="GeneID:855262"
/translation="MTKNVLMLHGLAQSGDYFASKTKGFRAEMEKLGYKLYYPTAPNE
FPPADVPDFLGEVIADAPGDGENTGVLAWLENDPSTGGYFIPQTTIDYLHNYVLENGP
FAGIVGFSQGAGVAGYLATDFNGLLGLTTEEQPPLEFFMAVSGFRFQPQQYQEQYDLH
PISVPSLHVQGELDTITEPAKVQGLYNSCTEDSRTLLMHSGGHFVPNSRGFVRKVAQW
LQQLT"
gene 716715..718130
/gene="UBP8"
/locus_tag="YMR223W"
/db_xref="GeneID:855263"
mRNA 716715..718130
/gene="UBP8"
/locus_tag="YMR223W"
/product="Ubp8p"
/transcript_id="NM_001182730.1"
/db_xref="GI:296147342"
/db_xref="GeneID:855263"
CDS 716715..718130
/gene="UBP8"
/locus_tag="YMR223W"
/EC_number="3.1.2.15"
/note="Ubiquitin-specific protease that is a component of
the SAGA (Spt-Ada-Gcn5-Acetyltransferase) acetylation
complex; required for SAGA-mediated deubiquitination of
histone H2B"
/codon_start=1
/product="Ubp8p"
/protein_id="NP_013950.1"
/db_xref="GI:6323879"
/db_xref="SGD:S000004836"
/db_xref="GeneID:855263"
/translation="MSICPHIQQVFQNEKSKDGVLKTCNAARYILNHSVPKEKFLNTM
KCGTCHEINSGATFMCLQCGFCGCWNHSHFLSHSKQIGHIFGINSNNGLLFCFKCEDY
IGNIDLINDAILAKYWDDVCTKTMVPSMERRDGLSGLINMGSTCFMSSILQCLIHNPY
FIRHSMSQIHSNNCKVRSPDKCFSCALDKIVHELYGALNTKQASSSSTSTNRQTGFIY
LLTCAWKINQNLAGYSQQDAHEFWQFIINQIHQSYVLDLPNAKEVSRANNKQCECIVH
TVFEGSLESSIVCPGCQNNSKTTIDPFLDLSLDIKDKKKLYECLDSFHKKEQLKDFNY
HCGECNSTQDAIKQLGIHKLPSVLVLQLKRFEHLLNGSNRKLDDFIEFPTYLNMKNYC
STKEKDKHSENGKVPDIIYELIGIVSHKGTVNEGHYIAFCKISGGQWFKFNDSMVSSI
SQEEVLKEQAYLLFYTIRQVN"
gene complement(718575..720653)
/gene="MRE11"
/locus_tag="YMR224C"
/gene_synonym="NGS1; RAD58; XRS4"
/db_xref="GeneID:855264"
mRNA complement(718575..720653)
/gene="MRE11"
/locus_tag="YMR224C"
/gene_synonym="NGS1; RAD58; XRS4"
/product="Mre11p"
/transcript_id="NM_001182731.1"
/db_xref="GI:296147343"
/db_xref="GeneID:855264"
CDS complement(718575..720653)
/gene="MRE11"
/locus_tag="YMR224C"
/gene_synonym="NGS1; RAD58; XRS4"
/note="Subunit of the MRX complex with Rad50p and Xrs2p;
complex functions in repair of DNA double-strand breaks
and in telomere stability; exhibits nuclease activity that
appears to be required for MRX function; widely conserved;
forms nuclear foci upon DNA replication stress"
/codon_start=1
/product="Mre11p"
/protein_id="NP_013951.1"
/db_xref="GI:6323880"
/db_xref="SGD:S000004837"
/db_xref="GeneID:855264"
/translation="MDYPDPDTIRILITTDNHVGYNENDPITGDDSWKTFHEVMMLAK
NNNVDMVVQSGDLFHVNKPSKKSLYQVLKTLRLCCMGDKPCELELLSDPSQVFHYDEF
TNVNYEDPNFNISIPVFGISGNHDDASGDSLLCPMDILHATGLINHFGKVIESDKIKV
VPLLFQKGSTKLALYGLAAVRDERLFRTFKDGGVTFEVPTMREGEWFNLMCVHQNHTG
HTNTAFLPEQFLPDFLDMVIWGHEHECIPNLVHNPIKNFDVLQPGSSVATSLCEAEAQ
PKYVFILDIKYGEAPKMTPIPLETIRTFKMKSISLQDVPHLRPHDKDATSKYLIEQVE
EMIRDANEETKQKLADDGEGDMVAELPKPLIRLRVDYSAPSNTQSPIDYQVENPRRFS
NRFVGRVANGNNVVQFYKKRSPVTRSKKSGINGTSISDRDVEKLFSESGGELEVQTLV
NDLLNKMQLSLLPEVGLNEAVKKFVDKDEKTALKEFISHEISNEVGILSTNEEFLRTD
DAEEMKALIKQVKRANSVRPTPPKENDETNFAFNGNGLDSFRSSNREVRTGSPDITQS
HVDNESRITHISQAESSKPTSKPKRVRTATKKKIPAFSDSTVISDAENELGDNNDAQD
DVDIDENDIIMVSTDEEDASYGLLNGRKTKTKTRPAASTKTASRRGKGRASRTPKTDI
LGSLLAKKRK"
gene complement(720960..721403)
/gene="MRPL44"
/locus_tag="YMR225C"
/gene_synonym="YMR44"
/db_xref="GeneID:855265"
mRNA complement(join(720960..721198,721346..721403))
/gene="MRPL44"
/locus_tag="YMR225C"
/gene_synonym="YMR44"
/product="mitochondrial 54S ribosomal protein YmL44"
/transcript_id="NM_001182732.1"
/db_xref="GI:296147344"
/db_xref="GeneID:855265"
CDS complement(join(720960..721198,721346..721403))
/gene="MRPL44"
/locus_tag="YMR225C"
/gene_synonym="YMR44"
/note="Mitochondrial ribosomal protein of the large
subunit; protein abundance increases in response to DNA
replication stress"
/codon_start=1
/product="mitochondrial 54S ribosomal protein YmL44"
/protein_id="NP_013952.1"
/db_xref="GI:6323881"
/db_xref="SGD:S000004838"
/db_xref="GeneID:855265"
/translation="MITKYFSKVIVRFNPFGKEAKVARLVLAAIPPTQRNMGTQIQSE
IISDYNKVKPLVKVTYKDKKEMEVDPSNMNFQELANHFDRHSKQLDLKHMLEMH"
gene complement(721593..722396)
/locus_tag="YMR226C"
/db_xref="GeneID:855266"
mRNA complement(721593..722396)
/locus_tag="YMR226C"
/product="oxidoreductase"
/transcript_id="NM_001182733.1"
/db_xref="GI:296147345"
/db_xref="GeneID:855266"
CDS complement(721593..722396)
/locus_tag="YMR226C"
/EC_number="1.-.-.-"
/note="NADP(+)-dependent dehydrogenase; acts on serine,
L-allo-threonine, and other 3-hydroxy acids; green
fluorescent protein fusion protein localizes to the
cytoplasm and nucleus; may interact with ribosomes, based
on co-purification experiments"
/codon_start=1
/product="oxidoreductase"
/protein_id="NP_013953.1"
/db_xref="GI:6323882"
/db_xref="SGD:S000004839"
/db_xref="GeneID:855266"
/translation="MSQGRKAAERLAKKTVLITGASAGIGKATALEYLEASNGDMKLI
LAARRLEKLEELKKTIDQEFPNAKVHVAQLDITQAEKIKPFIENLPQEFKDIDILVNN
AGKALGSDRVGQIATEDIQDVFDTNVTALINITQAVLPIFQAKNSGDIVNLGSIAGRD
AYPTGSIYCASKFAVGAFTDSLRKELINTKIRVILIAPGLVETEFSLVRYRGNEEQAK
NVYKDTTPLMADDVADLIVYATSRKQNTVIADTLIFPTNQASPHHIFRG"
gene complement(722613..724385)
/gene="TAF7"
/locus_tag="YMR227C"
/gene_synonym="TAF67"
/db_xref="GeneID:855267"
mRNA complement(722613..724385)
/gene="TAF7"
/locus_tag="YMR227C"
/gene_synonym="TAF67"
/product="Taf7p"
/transcript_id="NM_001182734.1"
/db_xref="GI:296147346"
/db_xref="GeneID:855267"
CDS complement(722613..724385)
/gene="TAF7"
/locus_tag="YMR227C"
/gene_synonym="TAF67"
/note="TFIID subunit (67 kDa), involved in RNA polymerase
II transcription initiation"
/codon_start=1
/product="Taf7p"
/protein_id="NP_013954.1"
/db_xref="GI:6323883"
/db_xref="SGD:S000004840"
/db_xref="GeneID:855267"
/translation="MAVIRIKKPRGPGEKDQPLEGEPKLKRIRIKTKVTDEDIKPKPK
LKINLKKKKESADGKEKKNSLKLKLNLKKNEEPVKKIHKAPKLRLKPIRIPGEAYDSE
ASDIEDDPLIESGVILRILPDIQLEFVKNSLESGDYSGISIKWKNERHAVVTINDVMY
GAILVDLPTVIEVNKSVDRKNLLKTFDVSQMLLCIRPIQEEEEVYALEAPDTEDLVVK
HFEGIEDEIWENKETFLKGYNGAPLSDMEAKHLKEIALKGYDYKHGISPPLYNVRNRR
FRRKMDPNEIDYVEKVVDMLLKQDKQAEEVSYDLVDKSELQARQERVSSWENFKEEPG
EPLSRPALKKEEIHTIASAVGKQGAEEEGEEGMEEEEEEDLDLGAAFESEEEGSGAEG
DKEQQQEEVGDEVDQDTGGEDDDDDDDGDIEAAGGESESDDEKDENRQHTELLADELN
ELETTLAHTKHKLSKATNPLLKSRFIDSIKKLEKEAELKRKQLQQTEDSVQKQHQHRS
DAETANNVEEEEEEEEEEEEEDEVDEDEEDDEENDEDEDNVHEREHIQENKVVRELDE
APAEETLDQNDLDMMMLFGAEGDE"
gene 724626..725651
/gene="MTF1"
/locus_tag="YMR228W"
/db_xref="GeneID:855268"
mRNA 724626..725651
/gene="MTF1"
/locus_tag="YMR228W"
/product="Mtf1p"
/transcript_id="NM_001182735.1"
/db_xref="GI:296147347"
/db_xref="GeneID:855268"
CDS 724626..725651
/gene="MTF1"
/locus_tag="YMR228W"
/note="Mitochondrial RNA polymerase specificity factor;
has structural similarity to
S-adenosylmethionine-dependent methyltransferases and
functional similarity to bacterial sigma-factors; Mtf1p
interacts with and stabilizes the Rpo41p-promoter complex,
enhancing DNA bending and melting to facilitate
pre-initiation open complex formation"
/codon_start=1
/product="Mtf1p"
/protein_id="NP_013955.1"
/db_xref="GI:6323884"
/db_xref="SGD:S000004841"
/db_xref="GeneID:855268"
/translation="MSVPIPGIKDISKLKFFYGFKYLWNPTVYNKIFDKLDLTKTYKH
PEELKVLDLYPGVGIQSAIFYNKYCPRQYSLLEKRSSLYKFLNAKFEGSPLQILKRDP
YDWSTYSNLIDEERIFVPEVQSSDHINDKFLTVANVTGEGSEGLIMQWLSCIGNKNWL
YRFGKVKMLLWMPSTTARKLLARPGMHSRSKCSVVREAFTDTKLIAISDANELKGFDS
QCIEEWDPILFSAAEIWPTKGKPIALVEMDPIDFDFDVDNWDYVTRHLMILKRTPLNT
VMDSLGHGGQQYFNSRITDKDLLKKCPIDLTNDEFIYLTKLFMEWPFKPDILMDFVDM
YQTEHSG"
gene complement(725934..731123)
/gene="RRP5"
/locus_tag="YMR229C"
/db_xref="GeneID:855269"
mRNA complement(725934..731123)
/gene="RRP5"
/locus_tag="YMR229C"
/product="Rrp5p"
/transcript_id="NM_001182736.1"
/db_xref="GI:296147348"
/db_xref="GeneID:855269"
CDS complement(725934..731123)
/gene="RRP5"
/locus_tag="YMR229C"
/note="RNA binding protein involved in synthesis of both
18S and 5.8S rRNAs; component of both the ribosomal small
subunit (SSU) processosome and the 90S preribosome; has
binding preference for single stranded tracts of U's;
relocalizes from nucleolus to nucleus upon DNA replication
stress"
/codon_start=1
/product="Rrp5p"
/protein_id="NP_013956.1"
/db_xref="GI:6323885"
/db_xref="SGD:S000004842"
/db_xref="GeneID:855269"
/translation="MVASTKRKRDEDFPLSREDSTKQPSTSSLVRNTEEVSFPRGGAS
ALTPLELKQVANEAASDVLFGNESVKASEPASRPLKKKKTTKKSTSKDSEASSANSDE
ARAGLIEHVNFKTLKNGSSLLGQISAITKQDLCITFTDGISGYVNLTHISEEFTSILE
DLDEDMDSDTDAADEKKSKVEDAEYESSDDEDEKLDKSNELPNLRRYFHIGQWLRCSV
IKNTSLEPSTKKSKKKRIELTIEPSSVNIYADEDLVKSTSIQCAVKSIEDHGATLDVG
LPGFTGFIAKKDFGNFEKLLPGAVFLGNITKKSDRSIVVNTDFSDKKNKITQISSIDA
IIPGQIVDLLCESITKNGIAGKVFGLVSGVVNVSHLRTFSEEDLKHKFVIGSSIRCRI
IACLENKSGDKVLILSNLPHILKLEDALRSTEGLDAFPIGYTFESCSIKGRDSEYLYL
ALDDDRLGKVHSSRVGEIENSENLSSRVLGYSPVDDIYQLSTDPKYLKLKYLRTNDIP
IGELLPSCEITSVSSSGIELKIFNGQFKASVPPLHISDTRLVYPERKFKIGSKVKGRV
ISVNSRGNVHVTLKKSLVNIEDNELPLVSTYENAKNIKEKNEKTLATIQVFKPNGCII
SFFGGLSGFLPNSEISEVFVKRPEEHLRLGQTVIVKLLDVDADRRRIIATCKVSNEQA
AQQKDTIENIVPGRTIITVHVIEKTKDSVIVEIPDVGLRGVIYVGHLSDSRIEQNRAQ
LKKLRIGTELTGLVIDKDTRTRVFNMSLKSSLIKDAKKETLPLTYDDVKDLNKDVPMH
AYIKSISDKGLFVAFNGKFIGLVLPSYAVDSRDIDISKAFYINQSVTVYLLRTDDKNQ
KFLLSLKAPKVKEEKKKVESNIEDPVDSSIKSWDDLSIGSIVKAKIKSVKKNQLNVIL
AANLHGRVDIAEVFDTYEEITDKKQPLSNYKKDDVIKVKIIGNHDVKSHKFLPITHKI
SKASVLELSMKPSELKSKEVHTKSLEEINIGQELTGFVNNSSGNHLWLTISPVLKARI
SLLDLADNDSNFSENIESVFPLGSALQVKVASIDREHGFVNAIGKSHVDINMSTIKVG
DELPGRVLKIAEKYVLLDLGNKVTGISFITDALNDFSLTLKEAFEDKINNVIPTTVLS
VDEQNKKIELSLRPATAKTRSIKSHEDLKQGEIVDGIVKNVNDKGIFVYLSRKVEAFV
PVSKLSDSYLKEWKKFYKPMQYVLGKVVTCDEDSRISLTLRESEINGDLKVLKTYSDI
KAGDVFEGTIKSVTDFGVFVKLDNTVNVTGLAHITEIADKKPEDLSALFGVGDRVKAI
VLKTNPEKKQISLSLKASHFSKEAELASTTTTTTTVDQLEKEDEDEVMADAGFNDSDS
ESDIGDQNTEVADRKPETSSDGLSLSAGFDWTASILDQAQEEEESDQDQEDFTENKKH
KHKRRKENVVQDKTIDINTRAPESVADFERLLIGNPNSSVVWMNYMAFQLQLSEIEKA
RELAERALKTINFREEAEKLNIWIAMLNLENTFGTEETLEEVFSRACQYMDSYTIHTK
LLGIYEISEKFDKAAELFKATAKKFGGEKVSIWVSWGDFLISHNEEQEARTILGNALK
ALPKRNHIEVVRKFAQLEFAKGDPERGRSLFEGLVADAPKRIDLWNVYVDQEVKAKDK
KKVEDLFERIITKKITRKQAKFFFNKWLQFEESEGDEKTIEYVKAKATEYVASHESQK
ADE"
gene 732414..733141
/gene="RPS10B"
/locus_tag="YMR230W"
/db_xref="GeneID:855270"
mRNA join(732414..732465,732876..733141)
/gene="RPS10B"
/locus_tag="YMR230W"
/product="ribosomal 40S subunit protein S10B"
/transcript_id="NM_001182737.1"
/db_xref="GI:296147349"
/db_xref="GeneID:855270"
CDS join(732414..732465,732876..733141)
/gene="RPS10B"
/locus_tag="YMR230W"
/note="Protein component of the small (40S) ribosomal
subunit; homologous to mammalian ribosomal protein S10, no
bacterial homolog; RPS10B has a paralog, RPS10A, that
arose from the whole genome duplication"
/codon_start=1
/product="ribosomal 40S subunit protein S10B"
/protein_id="NP_013957.1"
/db_xref="GI:6323886"
/db_xref="SGD:S000004843"
/db_xref="GeneID:855270"
/translation="MLMPKQERNKIHQYLFQEGVVVAKKDFNQAKHEEIDTKNLYVIK
ALQSLTSKGYVKTQFSWQYYYYTLTEEGVEYLREYLNLPEHIVPGTYIQERNPSQRPQ
RRY"
gene 733268..733456
/locus_tag="YMR230W-A"
/db_xref="GeneID:1466504"
mRNA 733268..733456
/locus_tag="YMR230W-A"
/product="hypothetical protein"
/transcript_id="NM_001184573.1"
/db_xref="GI:296147350"
/db_xref="GeneID:1466504"
CDS 733268..733456
/locus_tag="YMR230W-A"
/codon_start=1
/product="hypothetical protein"
/protein_id="NP_878146.1"
/db_xref="GI:33438858"
/db_xref="SGD:S000028576"
/db_xref="GeneID:1466504"
/translation="MCIIVKYSQCNLFFQDVLRCRHVLCMLFSIVVHFRLSSFVSVCG
VRIMCNCINCSRFIHNIN"
gene 733545..736634
/gene="PEP5"
/locus_tag="YMR231W"
/gene_synonym="END1; VAM1; VPL9; VPS11; VPT11"
/db_xref="GeneID:855271"
mRNA 733545..736634
/gene="PEP5"
/locus_tag="YMR231W"
/gene_synonym="END1; VAM1; VPL9; VPS11; VPT11"
/product="Pep5p"
/transcript_id="NM_001182738.1"
/db_xref="GI:296147351"
/db_xref="GeneID:855271"
CDS 733545..736634
/gene="PEP5"
/locus_tag="YMR231W"
/gene_synonym="END1; VAM1; VPL9; VPS11; VPT11"
/note="Histone E3 ligase, component of CORVET tethering
complex; peripheral vacuolar membrane protein required for
protein trafficking and vacuole biogenesis; interacts with
Pep7p; involved in ubiquitylation and degradation of
excess histones"
/codon_start=1
/product="Pep5p"
/protein_id="NP_013958.1"
/db_xref="GI:6323887"
/db_xref="SGD:S000004844"
/db_xref="GeneID:855271"
/translation="MSLSSWRQFQLFENIPIRDPNFGGDSLLYSDPTLCAATIVDPQT
LIIAVNSNIIKVVKLNQSQVIHEFQSFPHDFQITFLKVINGEFLVALAESIGKPSLIR
VYKLEKLPNREQLYHSQVELKNGNNTYPISVVSISNDLSCIVVGFINGKIILIRGDIS
RDRGSQQRIIYEDPSKEPITALFLNNDATACFAATTSRILLFNTTGRNRGRPSLVLNS
KNGLDLNCGSFNPATNEFICCLSNFIEFFSSSGKKHQFAFDLSLRKRIFCVDKDHILI
VTEETGVPTTSISVNELSPTIINRIFIIDAKNKIISLNFVVSSAIIDIFSTSQSGKNI
TYLLTSEGVMHRITPKSLENQINIIIQKELYPFALQLAKQHSLSPLDVQEIHKKYGDY
LFKKGLRKEATDQYIQCLDVVETSEIISKFGVKEVPDPESMRNLADYLWSLIKNSISQ
RDHVTLLLIVLIKLKDVEGIDTFIQHFDRKGIWNEGVVMDDMDDVTFFYSDNDFFDLD
LILELMKESDFKRLSYRLAKKYSKDSLIIVDILLNLLHNPVKAIKYIKSLPIDETLRC
LVTYSKKLLEESPNETNALLIEVFTGKFKPSTFEVDLDRRDTTGDFSENIRTVFYSYK
TFFNYMNSNGTSDAMSESSEASHEHEEPTYHPPKPSIVFSSFVTKPFEFVVFLEACLA
CYQQYEGFDEDRQVILTTLYDLYLNLAQNDVPERIDDWRSRATGVLRESNKLVYSAAS
NNTSKRVDNSIMLLISHMDQSSASAKDKTKIDIASFANDNPEMDLLSTFRAMTLNEEP
STCLKFLEKYGTEEPKLLQVALSYFVSNKLIFKEMGGNEVLKEKVLRPIIEGERMPLL
DIIKALSRTNVAHFGLIQDIIIDHVKTEDTEIKRNEKLIESYDKELKEKNKKLKNTIN
SDQPLHVPLKNQTCFMCRLTLDIPVVFFKCGHIYHQHCLNEEEDTLESERKLFKCPKC
LVDLETSNKLFEAQHEVVEKNDLLNFALNSEEGSRDRFKVITEFLGRGAISYSDITI"
gene 736926..738959
/gene="FUS2"
/locus_tag="YMR232W"
/db_xref="GeneID:855272"
mRNA 736926..738959
/gene="FUS2"
/locus_tag="YMR232W"
/product="Fus2p"
/transcript_id="NM_001182739.1"
/db_xref="GI:296147352"
/db_xref="GeneID:855272"
CDS 736926..738959
/gene="FUS2"
/locus_tag="YMR232W"
/note="Cytoplasmic protein localized to the shmoo tip;
required for the alignment of parental nuclei before
nuclear fusion during mating"
/codon_start=1
/product="Fus2p"
/protein_id="NP_013959.1"
/db_xref="GI:6323888"
/db_xref="SGD:S000004845"
/db_xref="GeneID:855272"
/translation="MFKTSYNLYDLNYPKNDSLTPIRDYKNDYFHKNDDKLPEIVRKP
TRKLSKHENKLNDKKFTNKRPASLDLHSIVESLSNKKIYSPINTEIFQNVVRLNLSPQ
IPNSPHEGCKFYKIVQEFYLSEVEYYNNLLTANNVYRKALNSDPRFKNKLVKLDSSDE
LLLFGNIDTIASISKILVTAIKDLLLAKQRGKMLDANEWQKIFTKNEVQQQLYSTFDI
SEAFEQHLLRIKSTYTSYFVSHQKQMELFTTLRMNKNHFFNKWYEYCLKESGCIKLED
ILKSPMKRLTQWIDTLETLESCYEDILSPELGLKLSPTRRKYSLFSNKLETEVSEYKS
NSMYNFSLTPSEIIQSYDEDQFTHLLKPPDKQNKNICNASRQESNLDNSRVPSLLSGS
SSYYSDVSGLEIVTNTSTASAEMINLKMDEETEFFTLADHISKFKKVMKGLLELKKNL
LKNDLSGIIDISLRRINAWKKVIECERPSGAFFAHDNLISTMCSSYIDKLHEQKNQVT
ILKLTELETDVMNPLERIIAHCTTVKSKLKDLQALKKDYMLFLQEKKANVRDIKRDLL
GMHFQNLQNQMKRELPVFITLIHDTIECILLNYIKVFLKYLEIIAGGKKYLQKDLENM
SLNDSIATGQIKNLDILQCYSKSRYMTKRMVRKDWPFPGDPSGSRVVRKLFEL"
gene 739185..739865
/gene="TRI1"
/locus_tag="YMR233W"
/db_xref="GeneID:855273"
mRNA 739185..739865
/gene="TRI1"
/locus_tag="YMR233W"
/product="Tri1p"
/transcript_id="NM_001182740.1"
/db_xref="GI:296147353"
/db_xref="GeneID:855273"
CDS 739185..739865
/gene="TRI1"
/locus_tag="YMR233W"
/note="Non-essential sumoylated hypothetical protein with
similarity to components of human SWI/SNF complex
including SMRD3; green fluorescent protein (GFP)-fusion
protein localizes to the cytoplasm, nucleus and nucleolus"
/codon_start=1
/product="Tri1p"
/protein_id="NP_013960.1"
/db_xref="GI:6323889"
/db_xref="SGD:S000004846"
/db_xref="GeneID:855273"
/translation="MADINKYIPMVDAILSVSNPDEISPKRVRKALQILYSVNLDSQR
KLINELILERFGDIQENPRVLIPKNDLISRDQELSLRLQKEEERPLRSTRKRKGKSES
KSKRKKKKNDSPDSNSISVRKVLLSAPLQKFLGSEELPRTQVVKMIWQYIKEHDLQNP
KDRREILCDEKMEPIFGKKMTMFSMNKLLTKHLFNPDEIVKHEEEQKQTPEKEIKLEN
ESLPNLSG"
gene 740266..741312
/gene="RNH1"
/locus_tag="YMR234W"
/db_xref="GeneID:855274"
mRNA 740266..741312
/gene="RNH1"
/locus_tag="YMR234W"
/product="Rnh1p"
/transcript_id="NM_001182741.1"
/db_xref="GI:296147354"
/db_xref="GeneID:855274"
CDS 740266..741312
/gene="RNH1"
/locus_tag="YMR234W"
/EC_number="3.1.26.4"
/note="Ribonuclease H1; able to bind double-stranded RNAs
and RNA-DNA hybrids; associates with RNAse polymerase I;
the homolog of mammalian RNAse HII (the S. cerevisiae
homolog of mammalian RNAse HI is RNH201)"
/codon_start=1
/product="Rnh1p"
/protein_id="NP_013961.1"
/db_xref="GI:6323890"
/db_xref="SGD:S000004847"
/db_xref="GeneID:855274"
/translation="MARQGNFYAVRKGRETGIYNTWNECKNQVDGYGGAIYKKFNSYE
QAKSFLGQPNTTSNYGSSTHAGGQVSKPHTTQKRVHRRNRPLHYSSLTSSSACSSLSS
ANTNTFYSVKSNVPNIESKIFNNWKDCQAYVKHKRGITFKKFEDQLAAENFISGMSAH
DYKLMNISKESFESKYKLSSNTMYNKSMNVYCDGSSFGNGTSSSRAGYGAYFEGAPEE
NISEPLLSGAQTNNRAEIEAVSEALKKIWEKLTNEKEKVNYQIKTDSEYVTKLLNDRY
MTYDNKKLEGLPNSDLIVPLVQRFVKVKKYYELNKECFKNNGKFQIEWVKGHDGDPGN
EMADFLAKKGASRR"
gene complement(741512..742735)
/gene="RNA1"
/locus_tag="YMR235C"
/db_xref="GeneID:855275"
mRNA complement(741512..742735)
/gene="RNA1"
/locus_tag="YMR235C"
/product="Rna1p"
/transcript_id="NM_001182742.1"
/db_xref="GI:296147355"
/db_xref="GeneID:855275"
CDS complement(741512..742735)
/gene="RNA1"
/locus_tag="YMR235C"
/note="GTPase activating protein (GAP) for Gsp1p, involved
in nuclear transport"
/codon_start=1
/product="Rna1p"
/protein_id="NP_013962.1"
/db_xref="GI:6323891"
/db_xref="SGD:S000004848"
/db_xref="GeneID:855275"
/translation="MATLHFVPQHEEEQVYSISGKALKLTTSDDIKPYLEELAALKTC
TKLDLSGNTIGTEASEALAKCIAENTQVRESLVEVNFADLYTSRLVDEVVDSLKFLLP
VLLKCPHLEIVNLSDNAFGLRTIELLEDYIAHAVNIKHLILSNNGMGPFAGERIGKAL
FHLAQNKKAASKPFLETFICGRNRLENGSAVYLALGLKSHSEGLKVVKLYQNGIRPKG
VATLIHYGLQYLKNLEILDLQDNTFTKHASLILAKALPTWKDSLFELNLNDCLLKTAG
SDEVFKVFTEVKFPNLHVLKFEYNEMAQETIEVSFLPAMEKGNLPELEKLEINGNRLD
EDSDALDLLQSKFDDLEVDDFEEVDSEDEEGEDEEDEDEDEKLEEIETERLEKELLEV
QVDDLAERLAETEIK"
gene 742971..743444
/gene="TAF9"
/locus_tag="YMR236W"
/gene_synonym="TAF17"
/db_xref="GeneID:855276"
mRNA 742971..743444
/gene="TAF9"
/locus_tag="YMR236W"
/gene_synonym="TAF17"
/product="Taf9p"
/transcript_id="NM_001182743.1"
/db_xref="GI:296147356"
/db_xref="GeneID:855276"
CDS 742971..743444
/gene="TAF9"
/locus_tag="YMR236W"
/gene_synonym="TAF17"
/note="Subunit (17 kDa) of TFIID and SAGA complexes,
involved in RNA polymerase II transcription initiation and
in chromatin modification, similar to histone H3"
/codon_start=1
/product="Taf9p"
/protein_id="NP_013963.1"
/db_xref="GI:6323892"
/db_xref="SGD:S000004849"
/db_xref="GeneID:855276"
/translation="MNGGGKNVLNKNSVGSVSEVGPDSTQEETPRDVRLLHLLLASQS
IHQYEDQVPLQLMDFAHRYTQGVLKDALVYNDYAGSGNSAGSGLGVEDIRLAIAARTQ
YQFKPTAPKELMLQLAAERNKKALPQVMGTWGVRLPPEKYCLTAKEWDLEDPKSM"
gene 743749..745923
/gene="BCH1"
/locus_tag="YMR237W"
/db_xref="GeneID:855277"
mRNA 743749..745923
/gene="BCH1"
/locus_tag="YMR237W"
/product="Bch1p"
/transcript_id="NM_001182744.1"
/db_xref="GI:296147357"
/db_xref="GeneID:855277"
CDS 743749..745923
/gene="BCH1"
/locus_tag="YMR237W"
/note="Member of the ChAPs family (Chs5p-Arf1p-binding
proteins); members include Bch1p, Bch2p, Bud7p, and Chs6p;
ChAPs family proteins form the exomer complex with Chs5p
to mediate export of specific cargo proteins from the
Golgi to the plasma membrane; may interact with ribosomes;
protein abundance increases and forms cytoplasmic foci in
response to DNA replication stress"
/codon_start=1
/product="Bch1p"
/protein_id="NP_013964.1"
/db_xref="GI:6323893"
/db_xref="SGD:S000004850"
/db_xref="GeneID:855277"
/translation="MLSQTSIPEVKEDVIGYALHQRRARVGQFQDLGPPDLITLIKSL
PSSSSTTTATASANDNGATSNINGQDPTTIVTELHSHDKLKGQIGTFFYCMGIDTSDP
TSITIFAKKITDLFLDTPQIWFGKKKHFHVSKISISSWNAFRKYDVNIIVHIPGTVQT
YIINSDGEQSQLPSVAEASSGRNSQDLNVNMIWAETFMSGIVRDIMIMKDNRADGESQ
NLVETLIFNPFTSGELEDVANNFIKLFPLVYEKGVYLDAPTHVLNPSLTNNYLVETLV
EIVRLTKSLEACRKMLKKLIEIHPEAVIILIRVYFACDLEIDAVDLINEQLNSPSSFL
ADDSKTSHIQLIFKSELLSIQSEFLLDVKRDYKLAKEVAMEAVNCAPNEFKTWYLLTR
IYIKLNDMSNALLSLNACPMSQVKEKYVLRRIAPITSDENLHLPLPLDASIEEISSLN
PMDVQLEQKSADPNLVNLSASSLKSTFQLAYKLLTEIVQITGWEQLLKYRSKIFVMED
EYQGSTSSIDEAEVRGNDISKMRSKRLCERWLDNLFMLLYEDLKTYTDWQSEQLYFDA
QNSKYHKLTVEWELFGLCAKRLGHLPEAAKAFQIGLSQRFSPVCAKNLLQFYIDEHKR
IRRDSVSANSELTSSQILSSINDIDSSIIDLVVKICCWNHRWYIEFSIILIDALSVAV
QDMGITKVHNEIASRFSDPVAQLIDDNILNFLKNFTNDTFDN"
gene 746353..747729
/gene="DFG5"
/locus_tag="YMR238W"
/db_xref="GeneID:855278"
mRNA 746353..747729
/gene="DFG5"
/locus_tag="YMR238W"
/product="Dfg5p"
/transcript_id="NM_001182745.1"
/db_xref="GI:296147358"
/db_xref="GeneID:855278"
CDS 746353..747729
/gene="DFG5"
/locus_tag="YMR238W"
/EC_number="3.2.1.101"
/note="Putative mannosidase, essential
glycosylphosphatidylinositol (GPI)-anchored membrane
protein required for cell wall biogenesis in bud
formation, involved in filamentous growth, homologous to
Dcw1p"
/codon_start=1
/product="Dfg5p"
/protein_id="NP_013965.1"
/db_xref="GI:6323894"
/db_xref="SGD:S000004851"
/db_xref="GeneID:855278"
/translation="MIVNISAKMILSICFTFLSFFKATHAMDLDTTSKTSICDATALI
QGGMLDYYEGTRYGGTVGMFQSPYYWWHAGEAFGGMLENWFLCENDTYQELLYDALLA
QTGSNYDYIPSNQTMVEGNDDQGIWGITVMGAVERNFTDPGDGKPGWLAMVQAVFNTM
YSRWDSEHCGGGLRWQIFTWNSGYNYKNTVSNACLFQIAARLGRYTGNTTYLEVAEQV
FDWLVDVGYVVLNDTANVFDGAEIDTNCTDITKIEWTYNHGIVLGGLAYMYNATNGTG
EWETSLTKILNGAKSYFFKDSIMYESACQDYGTCNTDQRTFKSIFSRMLGLTSVMAPF
TRDTIDDLIKTSAEAAAKSCNGGTDGHTCGLNWQKQTNDGYYGLGEQMSALEVIQNLL
IHDRPAPYKEDNGGTSKGDANAGMNSSTTNVLQNNLNIKKGDRAGAAIITAVILSVLT
GGAVWMLF"
gene complement(747892..747963)
/locus_tag="tR(UCU)M1"
/db_xref="GeneID:855279"
tRNA complement(747892..747963)
/locus_tag="tR(UCU)M1"
/product="tRNA-Arg"
/note="Arginine tRNA (tRNA-Arg), predicted by tRNAscan-SE
analysis; one of 11 nuclear tRNA genes containing the
tDNA-anticodon UCU (converted to mcm5-UCU in the mature
tRNA), decodes AGA codons into arginine, one of 19 nuclear
tRNAs for arginine"
/db_xref="SGD:S000006717"
/db_xref="GeneID:855279"
gene complement(748262..749677)
/gene="RNT1"
/locus_tag="YMR239C"
/db_xref="GeneID:855280"
mRNA complement(748262..749677)
/gene="RNT1"
/locus_tag="YMR239C"
/product="Rnt1p"
/transcript_id="NM_001182746.1"
/db_xref="GI:296147359"
/db_xref="GeneID:855280"
CDS complement(748262..749677)
/gene="RNT1"
/locus_tag="YMR239C"
/EC_number="3.1.26.3"
/note="Nuclear dsRNA-specific ribonuclease (RNase III);
involved in rDNA transcription, rRNA processing and U2
snRNA 3' end formation by cleavage of a stem-loop
structure at the 3' end of U2 snRNA; involved in
polyadenylation-independent transcription termination;
involved in the cell wall stress response, regulating the
degradation of cell wall integrity and morphogenesis
checkpoint genes"
/codon_start=1
/product="Rnt1p"
/protein_id="NP_013966.1"
/db_xref="GI:6323895"
/db_xref="SGD:S000004852"
/db_xref="GeneID:855280"
/translation="MGSKVAGKKKTQNDNKLDNENGSQQRENINTKTLLKGNLKISNY
KYLEVIQLEHAVTKLVESYNKIIELSPNLVAYNEAVNNQDRVPVQILPSLSRYQLKLA
AELKTLHDLKKDAILTEITDYENEFDTEQKQPILQEISKADMEKLEKLEQVKREKREK
IDVNVYENLNEKEDEEEDEGEDSYDPTKAGDIVKATKWPPKLPEIQDLAIRARVFIHK
STIKDKVYLSGSEMINAHNERLEFLGDSILNSVMTLIIYNKFPDYSEGQLSTLRMNLV
SNEQIKQWSIMYNFHEKLKTNFDLKDENSNFQNGKLKLYADVFEAYIGGLMEDDPRNN
LPKIRKWLRKLAKPVIEEATRNQVALEKTDKLDMNAKRQLYSLIGYASLRLHYVTVKK
PTAVDPNSIVECRVGDGTVLGTGVGRNIKIAGIRAAENALRDKKMLDFYAKQRAAIPR
SESVLKDPSQKNKKRKFSDTS"
gene complement(749930..751240)
/gene="CUS1"
/locus_tag="YMR240C"
/db_xref="GeneID:855281"
mRNA complement(749930..751240)
/gene="CUS1"
/locus_tag="YMR240C"
/product="Cus1p"
/transcript_id="NM_001182747.1"
/db_xref="GI:296147360"
/db_xref="GeneID:855281"
CDS complement(749930..751240)
/gene="CUS1"
/locus_tag="YMR240C"
/note="Protein required for assembly of U2 snRNP into the
spliceosome, forms a complex with Hsh49p and Hsh155p"
/codon_start=1
/product="Cus1p"
/protein_id="NP_013967.1"
/db_xref="GI:6323896"
/db_xref="SGD:S000004853"
/db_xref="GeneID:855281"
/translation="MARTKSRKRSGNNQNKNASVVNNKAEIAAMIDARRLEQKKKGGV
TNSKGKTNKVVDAKLEKEFKDVLQRFQVQENDTPKEITKDEKNNHVVIVEKNPVMNRK
HTAEDELEDTPSDGIEEHLSARKRRKTEKPSLSQLKSQVPYPQIIEWYDCDARYPGLL
ASIKCTKNVIPVPSHWQSKKEYLSGRSLLGKRPFELPDIIKKTNIEQMRSTLPQSGLD
GQDEKSLKEASRARVQPKMGALDLDYKKLHDVFFKIGANWKPDHLLCFGDVYYENRNL
FEETNWKRMVDHKRPGRISQELRAIMNLPEGQLPPWCMKMKDIGLPTGYPDLKIAGLN
WDITNLKGDVYGKIIPNHHSRSKKQGRNYFGALISFETPEFENSKEDTQANAENGRQD
DKIDDEVEHKLDHFQEDISEVTSAEEKLERNEEESEKQLYTVLK"
gene 751961..752905
/gene="YHM2"
/locus_tag="YMR241W"
/db_xref="GeneID:855282"
mRNA 751961..752905
/gene="YHM2"
/locus_tag="YMR241W"
/product="Yhm2p"
/transcript_id="NM_001182748.1"
/db_xref="GI:296147361"
/db_xref="GeneID:855282"
CDS 751961..752905
/gene="YHM2"
/locus_tag="YMR241W"
/note="Carrier protein that exports citrate from and
imports oxoglutarate into the mitochondrion, causing net
export of NADPH reducing equivalents; also associates with
mt nucleoids and has a role in replication and segregation
of the mt genome"
/codon_start=1
/product="Yhm2p"
/protein_id="NP_013968.1"
/db_xref="GI:6323897"
/db_xref="SGD:S000004854"
/db_xref="GeneID:855282"
/translation="MPSTTNTAAANVIEKKPVSFSNILLGACLNLSEVTTLGQPLEVV
KTTMAANRNFTFLESVKHVWSRGGILGYYQGLIPWAWIEASTKGAVLLFVSAEAEYRF
KSLGLNNFASGILGGVTGGVTQAYLTMGFCTCMKTVEITRHKSASAGGVPQSSWSVFK
NIYKKEGIRGINKGVNAVAIRQMTNWGSRFGLSRLVEDGIRKITGKTNKDDKLNPFEK
IGASALGGGLSAWNQPIEVIRVEMQSKKEDPNRPKNLTVGKTFKYIYQSNGLKGLYRG
VTPRIGLGIWQTVFMVGFGDMAKEFVARMTGETPVAKH"
gene complement(753225..754220)
/gene="RPL20A"
/locus_tag="YMR242C"
/gene_synonym="RPL18A2"
/db_xref="GeneID:855283"
mRNA complement(join(753225..753742,754220))
/gene="RPL20A"
/locus_tag="YMR242C"
/gene_synonym="RPL18A2"
/product="ribosomal 60S subunit protein L20A"
/transcript_id="NM_001182749.1"
/db_xref="GI:296147362"
/db_xref="GeneID:855283"
CDS complement(join(753225..753742,754220))
/gene="RPL20A"
/locus_tag="YMR242C"
/gene_synonym="RPL18A2"
/note="Ribosomal 60S subunit protein L20A; homologous to
mammalian ribosomal protein L18A, no bacterial homolog;
RPL20A has a paralog, RPL20B, that arose from the whole
genome duplication"
/codon_start=1
/product="ribosomal 60S subunit protein L20A"
/protein_id="NP_013969.3"
/db_xref="GI:154199621"
/db_xref="SGD:S000004855"
/db_xref="GeneID:855283"
/translation="MAHFKEYQVIGRRLPTESVPEPKLFRMRIFASNEVIAKSRYWYF
LQKLHKVKKASGEIVSINQINEAHPTKVKNFGVWVRYDSRSGTHNMYKEIRDVSRVAA
VETLYQDMAARHRARFRSIHILKVAEIEKTADVKRQYVKQFLTKDLKFPLPHRVQKST
KTFSYKRPSTFY"
gene 754297..754386
/locus_tag="YMR242W-A"
/db_xref="GeneID:1466505"
mRNA 754297..754386
/locus_tag="YMR242W-A"
/product="hypothetical protein"
/transcript_id="NM_001184616.1"
/db_xref="GI:296147363"
/db_xref="GeneID:1466505"
CDS 754297..754386
/locus_tag="YMR242W-A"
/codon_start=1
/product="hypothetical protein"
/protein_id="NP_878147.1"
/db_xref="GI:33438859"
/db_xref="SGD:S000028694"
/db_xref="GeneID:1466505"
/translation="MFKMKFGDTLPRSDFGTGGNKQAPGLELG"
gene complement(754838..756166)
/gene="ZRC1"
/locus_tag="YMR243C"
/gene_synonym="OSR1"
/db_xref="GeneID:855284"
mRNA complement(754838..756166)
/gene="ZRC1"
/locus_tag="YMR243C"
/gene_synonym="OSR1"
/product="Zn(2+) transporter ZRC1"
/transcript_id="NM_001182750.1"
/db_xref="GI:296147364"
/db_xref="GeneID:855284"
CDS complement(754838..756166)
/gene="ZRC1"
/locus_tag="YMR243C"
/gene_synonym="OSR1"
/note="Vacuolar membrane zinc transporter; transports zinc
from cytosol to vacuole for storage; also has role in
resistance to zinc shock resulting from sudden influx of
zinc into cytoplasm; human ortholog SLC30A10 functions as
a Mn transporter and mutations in SLC30A10 cause
neurotoxic accumulation of Mn in liver and brain; ZRC1 has
a paralog, COT1, that arose from the whole genome
duplication"
/codon_start=1
/product="Zn(2+) transporter ZRC1"
/protein_id="NP_013970.1"
/db_xref="GI:6323899"
/db_xref="SGD:S000004856"
/db_xref="GeneID:855284"
/translation="MITGKELRIISLLTLDTVFFLLEITIGYMSHSLALIADSFHMLN
DIISLLVALWAVDVAKNRGPDAKYTYGWKRAEILGALINAVFLIALCFSIMIEALQRL
IEPQEIQNPRLVLYVGVAGLISNVVGLFLFHDHGSDSLHSHSHGSVESGNNDLDIESN
ATHSHSHASLPNDNLAIDEDAISSPGPSGQIGEVLPQSVVNRLSNESQPLLNHDDHDH
SHESKKPGHRSLNMHGVFLHVLGDALGNIGVIAAALFIWKTEYSWRYYSDPIVSLIIT
IIIFSSALPLSRRASRILLQATPSTISADQIQREILAVPGVIAVHDFHVWNLTESIYI
ASIHVQIDCAPDKFMSSAKLIRKIFHQHGIHSATVQPEFVSGDVNEDIRRRFSIIAGG
SPSSSQEAFDSHGNTEHGRKKRSPTAYGATTASSNCIVDDAVNCNTSNCL"
gene 757250..758317
/locus_tag="YMR244W"
/db_xref="GeneID:855285"
mRNA 757250..758317
/locus_tag="YMR244W"
/product="hypothetical protein"
/transcript_id="NM_001182752.1"
/db_xref="GI:296147365"
/db_xref="GeneID:855285"
CDS 757250..758317
/locus_tag="YMR244W"
/codon_start=1
/product="hypothetical protein"
/protein_id="NP_013971.1"
/db_xref="GI:6323900"
/db_xref="SGD:S000004858"
/db_xref="GeneID:855285"
/translation="MVLCKLLTPYFLLSILSVGVFTATAAPSPSIQMTENTNQDHHEH
AKRGGTCAFPNYDGMVAVQKGGSNGGWAMSPDQECSYGSWCPYACKPGQLMGQWDPSA
TTYSYPKCQNGGLYCDSNGNLQKPNSDKDYCYDGKGTVIAKNNANSGDVAFCQTVLPG
NEAMLIPTLVGSGSKQTLAVPGTDYWASSASHYYVNAPGVSVEDACQWGSSANPQGNW
APFVAGSNMDDNQNTFVKIGWNPVYLESSCPFKNVKPSFGIRITCDDESQCEGLPCSI
DPSSNGVNEVTSSGGGSSGAGGGNFCVVTARNGAKANIEVFDVGSGSSSKGKRELNPL
DVITTTVTETKYKTVTVTAKT"
rep_origin 758224..758471
/note="ARS1327;
Autonomously Replicating Sequence"
/db_xref="SGD:S000118377"
gene complement(758517..758831)
/gene="COA6"
/locus_tag="YMR244C-A"
/db_xref="GeneID:855287"
mRNA complement(758517..758831)
/gene="COA6"
/locus_tag="YMR244C-A"
/product="Coa6p"
/transcript_id="NM_001182751.1"
/db_xref="GI:296147366"
/db_xref="GeneID:855287"
CDS complement(758517..758831)
/gene="COA6"
/locus_tag="YMR244C-A"
/note="Protein involved in cytochrome c oxidase assembly;
also required for efficient formation of respiratory
supercomplexes comprised of Complexes III and IV;
localizes to the mitochondrial intermembrane space; has a
human homolog; transcription is induced in response to the
DNA-damaging agent MMS; protein abundance increases in
response to DNA replication stress"
/codon_start=1
/product="Coa6p"
/protein_id="NP_013972.1"
/db_xref="GI:6323902"
/db_xref="SGD:S000004857"
/db_xref="GeneID:855287"
/translation="MGLFSFDGGKKESQPPNTRSQRKLCWESRDAFFQCLDKADILDA
MDPKNSKSIKSHCKVENEKFEENCAHSWIKYFKEKRVIDFKREQTIKRIEQEAKQRER
NQ"
gene 759807..761891
/gene="FAA4"
/locus_tag="YMR246W"
/db_xref="GeneID:855288"
mRNA 759807..761891
/gene="FAA4"
/locus_tag="YMR246W"
/product="long-chain fatty acid-CoA ligase FAA4"
/transcript_id="NM_001182754.1"
/db_xref="GI:296147367"
/db_xref="GeneID:855288"
CDS 759807..761891
/gene="FAA4"
/locus_tag="YMR246W"
/EC_number="6.2.1.3"
/note="Long chain fatty acyl-CoA synthetase; activates
imported fatty acids with a preference for C12:0-C16:0
chain lengths; functions in long chain fatty acid import;
important for survival during stationary phase; localized
to lipid particles; involved in
sphingolipid-to-glycerolipid metabolism; forms cytoplasmic
foci upon DNA replication stress; FAA4 has a paralog,
FAA1, that arose from the whole genome duplication"
/codon_start=1
/product="long-chain fatty acid-CoA ligase FAA4"
/protein_id="NP_013974.1"
/db_xref="GI:6323903"
/db_xref="SGD:S000004860"
/db_xref="GeneID:855288"
/translation="MTEQYSVAVGEAANEHETAPRRNIRVKDQPLIRPINSSASTLYE
FALECFTKGGKRDGMAWRDIIDIHETKKTIVKRVDGKDKPIEKTWLYYELTPYITMTY
EEMICVMHDIGRGLIKIGVKPNGENKFHIFASTSHKWMKTFLGCMSQGIPVVTAYDTL
GESGLIHSMVETDSVAIFTDNQLLSKLAVPLKTAKNVKFVIHNEPIDPSDKRQNGKLY
KAAKDAVDKIKEVRPDIKIYSFDEIIEIGKKAKDEVELHFPKPEDPACIMYTSGSTGT
PKGVVLTHYNIVAGIGGVGHNVIGWIGPTDRIIAFLPLAHIFELTFEFEAFYWNGILG
YANVKTLTPTSTRNCQGDLMEFKPTVMVGVAAVWETVRKGILAKINELPGWSQTLFWT
VYALKERNIPCSGLLSGLIFKRIREATGGNLRFILNGGSAISIDAQKFLSNLLCPMLI
GYGLTEGVANACVLEPEHFDYGIAGDLVGTITAKLVDVEDLGYFAKNNQGELLFKGAP
ICSEYYKNPEETAAAFTDDGWFRTGDIAEWTPKGQVKIIDRKKNLVKTLNGEYIALEK
LESIYRSNPYVQNICVYADENKVKPVGIVVPNLGHLSKLAIELGIMVPGEDVESYIHE
KKLQDAVCKDMLSTAKSQGLNGIELLCGIVFFEEEWTPENGLVTSAQKLKRRDILAAV
KPDVERVYKENT"
gene complement(762110..763113)
/locus_tag="snR86"
/db_xref="GeneID:9164959"
ncRNA complement(762110..763113)
/locus_tag="snR86"
/ncRNA_class="snoRNA"
/product="SNR86"
/note="H/ACA box small nucleolar RNA (snoRNA); guides
pseudouridylation of large subunit (LSU) rRNA at position
U2314"
/db_xref="SGD:S000119075"
/db_xref="GeneID:9164959"
gene complement(763351..768039)
/gene="RKR1"
/locus_tag="YMR247C"
/gene_synonym="LTN1"
/db_xref="GeneID:855289"
mRNA complement(763351..768039)
/gene="RKR1"
/locus_tag="YMR247C"
/gene_synonym="LTN1"
/product="ubiquitin-protein ligase RKR1"
/transcript_id="NM_001182755.1"
/db_xref="GI:296147368"
/db_xref="GeneID:855289"
CDS complement(763351..768039)
/gene="RKR1"
/locus_tag="YMR247C"
/gene_synonym="LTN1"
/note="RING domain E3 ubiquitin ligase; involved in the
ubiquitin-mediated degradation of non-stop proteins;
functional connections to chromatin modification; nuclear
protein that also co-localizes with ribosomes; homolog of
mouse Listerin, whose mutation has been reported to cause
neurodegeneration in mice"
/codon_start=1
/product="ubiquitin-protein ligase RKR1"
/protein_id="NP_013975.1"
/db_xref="GI:6323904"
/db_xref="SGD:S000004861"
/db_xref="GeneID:855289"
/translation="MSFGGINTFQQYNTDLGLGHNGVRISLNYFDGLPDPSLLNSLYS
NELKLIFKSLLKRDETTKEKALMDLSNLISDFNQNEYFFNDIFLLCWSQIYAKLIISD
YKVIRLQSHQITIMLVKSLRKKISKFLKDFIPLILLGTCELDYSVSKPSLNELTECFN
KDPAKINALWAVFQEQLLNLVKEIVVNENEDTISDERYSSKEESEFRYHRVIASAVLL
LIKLFVHNKDVSERNSSSLKVILSDESIWKLLNLKNGQNTNAYETVLRLIDVLYTRGY
MPSHKNIMKLAVKKLLKSLTHITSKNILKVCPVLPSILNLLATLDDYEDGTIWSYDKS
SKEKVLKFLSVSRTSPSPGFFNAVFALYSSTKRHSFLDYYLEWLPFWQKSVQRLNEKG
FSARNSAEVLNEFWTNFLKFAEDSSEERVKKMVESEIFNSLSCGKSLSEYTKLNQTLS
GVFPPDKWEREIEDYFTSDEDIRKIKVSFEKNLFALLVTSPNNESAISRLFDFFVQLI
ETDPSNVFNKYDGVYDALNYFLDSDMIFLNGKIGKFINEIPTLVQESTYQNFAGIMAQ
YSNSKFFKMNTDAITSLEDFFIVALSFNLPKTIILATMNELDNDIYQQLMKSDSLELE
LYIEDFMKNYKFDDSGEIFKGNNKFLNQRTITTLYRSAVANGQVEQFCAVLSKLDETF
FSTLLLNTDFLSCALYEVSEDTNEKLFKLSLQLAKGNSEIANKLAQVILQHAQVYFSP
GAKEKYVTHAVELINGCNDTSQIFFPANAIEVFARYMPAIDYRSSLVSSLSTNTHLLL
TDDKPINLKNMQKLIRYALFLDALLDALPERVNNHIVAFITVVSELVTDYNCLSEEPN
DLYYDFGHTFFKHGKVNLNFSDIVGNVIQPANGGDAMLTFDIAESNSVYFFYYSRVLY
KVLLNSIDTVSSTTLNGLLASVESFVTKTVRDQKSTDKDYLLCAILLLMFNRSNSKDE
ITKLRTLLASQLIGIREVELVDQEFKSLALLNNLLDIPQADKQFVPIAPQRLNMIFRS
ILKWLDSDLAYEPSFSTVRLLLLDFFTKLMRFEGVRDMGITAFELSERLLADSLSMCQ
IDDTLYLLELRSSCLNLYETLSQGVSKNGEEISEYGDEIQENLIELMFLNFNQERNNQ
VSTLFYQKLYKVISSMELKKLESQYKRIFEVVLNDKDIGSNINQSRLLTTLLGSLVVK
TQQDIIIEYELRIQKQTGSDVDGSASDNDVNSKFKLPQKLLQKVTDEVPKEYLEYENK
NSFIKYLWYWHLILMYFKDTSYNMRQIFIEQLKEAGLINRMFDFITDQIDLRDTEFWK
QVDTKEISEYNIVGNNFSPYKEDIFEECKKLLGHTLYQLFNNVGCLTSIWWLNIKDRT
LQNDIEKFVSEFISPILIKNEFDDINSKMDRLTSNDDALTIKLNNITNEVKASYLIDD
QKLEISFKLPKNYPLTNIQVNGVSRVGISEQKWKQWIMSTQHVITGMNGSVLDSLELF
TKNVHLQFSGFEECAICYSILHAVDRKLPSKTCPTCKNKFHGACLYKWFRSSGNNTCP
LCRSEIPFRR"
gene complement(768369..768441)
/locus_tag="tA(AGC)M2"
/db_xref="GeneID:855290"
tRNA complement(768369..768441)
/locus_tag="tA(AGC)M2"
/product="tRNA-Ala"
/note="Alanine tRNA (tRNA-Ala), predicted by tRNAscan-SE
analysis; one of 11 nuclear tRNA genes containing the
tDNA-anticodon AGC (converted to IGC in the mature tRNA),
decodes GCU and GCC codons into alanine, one of 16 nuclear
tRNAs for alanine"
/db_xref="SGD:S000006519"
/db_xref="GeneID:855290"
LTR 768548..768879
/note="Ty2 LTR"
/db_xref="SGD:S000007125"
gene 769283..769426
/locus_tag="YMR247W-A"
/db_xref="GeneID:1466506"
mRNA 769283..769426
/locus_tag="YMR247W-A"
/product="hypothetical protein"
/transcript_id="NM_001184661.1"
/db_xref="GI:296147369"
/db_xref="GeneID:1466506"
CDS 769283..769426
/locus_tag="YMR247W-A"
/codon_start=1
/product="hypothetical protein"
/protein_id="NP_878148.1"
/db_xref="GI:33438860"
/db_xref="SGD:S000028849"
/db_xref="GeneID:1466506"
/translation="MAHKCASAKLLSGIMALLFNGKSLLRPICLHVHNHLVSNSDTNI
VWP"
gene 770801..772558
/gene="GAD1"
/locus_tag="YMR250W"
/db_xref="GeneID:855291"
mRNA 770801..772558
/gene="GAD1"
/locus_tag="YMR250W"
/product="glutamate decarboxylase GAD1"
/transcript_id="NM_001182756.1"
/db_xref="GI:296147370"
/db_xref="GeneID:855291"
CDS 770801..772558
/gene="GAD1"
/locus_tag="YMR250W"
/EC_number="4.1.1.15"
/note="Glutamate decarboxylase, converts glutamate into
gamma-aminobutyric acid (GABA) during glutamate
catabolism; involved in response to oxidative stress"
/codon_start=1
/product="glutamate decarboxylase GAD1"
/protein_id="NP_013976.1"
/db_xref="GI:6323905"
/db_xref="SGD:S000004862"
/db_xref="GeneID:855291"
/translation="MLHRHGSKQKNFENIAGKVVHDLAGLQLLSNDVQKSAVQSGHQG
SNNMRDTSSQGMANKYSVPKKGLPADLSYQLIHNELTLDGNPHLNLASFVNTFTTDQA
RKLIDENLTKNLADNDEYPQLIELTQRCISMLAQLWHANPDEEPIGCATTGSSEAIML
GGLAMKKRWEHRMKNAGKDASKPNIIMSSACQVALEKFTRYFEVECRLVPVSHRSHHM
LDPESLWDYVDENTIGCFVILGTTYTGHLENVEKVADVLSQIEAKHPDWSNTDIPIHA
DGASGGFIIPFGFEKEHMKAYGMERWGFNHPRVVSMNTSGHKFGLTTPGLGWVLWRDE
SLLADELRFKLKYLGGVEETFGLNFSRPGFQVVHQYFNFVSLGHSGYRTQFQNSLFVA
RAFSFELLNSSKLPGCFEIVSSIHESIENDSAPKSVKDYWEHPQAYKPGVPLVAFKLS
KKFHEEYPEVPQAILSSLLRGRGWIIPNYPLPKATDGSDEKEVLRVVFRSEMKLDLAQ
LLIVDIESILTKLIHSYEKVCHHIELASEQTPERKSSFIYEMLLALASPQDDIPTPDE
IEKKNKLKETTTRNYRGTC"
rep_origin 772631..772879
/note="ARS1328;
Autonomously Replicating Sequence"
/db_xref="SGD:S000118378"
gene 772915..774015
/gene="GTO3"
/locus_tag="YMR251W"
/db_xref="GeneID:855292"
mRNA 772915..774015
/gene="GTO3"
/locus_tag="YMR251W"
/product="Gto3p"
/transcript_id="NM_001182757.1"
/db_xref="GI:296147371"
/db_xref="GeneID:855292"
CDS 772915..774015
/gene="GTO3"
/locus_tag="YMR251W"
/EC_number="2.5.1.18"
/note="Omega class glutathione transferase; putative
cytosolic localization"
/codon_start=1
/product="Gto3p"
/protein_id="NP_013977.1"
/db_xref="GI:6323906"
/db_xref="SGD:S000004863"
/db_xref="GeneID:855292"
/translation="MSEKSASNNKAEFKRQSSPFREIISADHPIYKPAKGRYWLYVAL
PCPWAQRTLITRALKGLAPIIGCSVAHWHLDDKGWRFLEEGDGKTNERHWFDIAGGIS
SVNLNTSTPVANIPNNAHRLLVDGTDEPHYGYKRLSDFYFKTKPDYKGRFTVPVLWDL
ETCTIVNNESSDIIGIMNSAAFDEFVGEEYRQVRLVPRSLEAQITEFNSWVYDKINNG
VYKAGFAECAEVYEREVTSLFQYLDKLENLLDKKYTDLEAEYGKNNKDKILDRYFAIG
DTLTEADVRLYPTIVRFDVVYHQHFKCNLATIRDDYSRIHTWLKNIYWRHEAFQRTTD
FTHIKLGYTRSQPRVNPIGITPLGPKPDIRPP"
gene 774752..774931
/gene="HOR7"
/locus_tag="YMR251W-A"
/db_xref="GeneID:855293"
mRNA 774752..774931
/gene="HOR7"
/locus_tag="YMR251W-A"
/product="Hor7p"
/transcript_id="NM_001182758.1"
/db_xref="GI:296147372"
/db_xref="GeneID:855293"
CDS 774752..774931
/gene="HOR7"
/locus_tag="YMR251W-A"
/note="hypothetical protein; overexpression suppresses
Ca2+ sensitivity of mutants lacking inositol
phosphorylceramide mannosyltransferases Csg1p and Csh1p;
transcription is induced under hyperosmotic stress and
repressed by alpha factor"
/codon_start=1
/product="Hor7p"
/protein_id="NP_013978.1"
/db_xref="GI:6323907"
/db_xref="SGD:S000004864"
/db_xref="GeneID:855293"
/translation="MKLSQVVVSAVAFTGLVSAANSSNSSSSKNAAQPIAGLNNGKVA
GAAGVALAGALAFLI"
gene complement(775315..775719)
/locus_tag="YMR252C"
/db_xref="GeneID:855294"
mRNA complement(775315..775719)
/locus_tag="YMR252C"
/product="hypothetical protein"
/transcript_id="NM_001182759.1"
/db_xref="GI:296147373"
/db_xref="GeneID:855294"
CDS complement(775315..775719)
/locus_tag="YMR252C"
/note="hypothetical protein; green fluorescent protein
(GFP)-fusion protein localizes to mitochondria; YMR252C is
not an essential gene"
/codon_start=1
/product="hypothetical protein"
/protein_id="NP_013979.1"
/db_xref="GI:6323908"
/db_xref="SGD:S000004865"
/db_xref="GeneID:855294"
/translation="MFGKVFVSYIRTRIGFKPLSTIYTPVSSSSLSFDKEACFPFKKW
HELNMSQKQEFIQRFVKNYRHQYPSSKTNVSLKGLSIGMDEHNDSPSVFGIFYNDIWK
SFKNEQLGTNNDNMKSGSRFSHPSFKQLLIQK"
gene complement(775946..777190)
/locus_tag="YMR253C"
/db_xref="GeneID:855295"
mRNA complement(775946..777190)
/locus_tag="YMR253C"
/product="hypothetical protein"
/transcript_id="NM_001182760.1"
/db_xref="GI:296147374"
/db_xref="GeneID:855295"
CDS complement(775946..777190)
/locus_tag="YMR253C"
/note="hypothetical protein; green fluorescent protein
(GFP)-fusion protein localizes to the cytoplasm in a
punctate pattern; YMR253C is not an essential gene"
/codon_start=1
/product="hypothetical protein"
/protein_id="NP_013980.1"
/db_xref="GI:6323909"
/db_xref="SGD:S000004866"
/db_xref="GeneID:855295"
/translation="MNPSVPKVMKRENNTHLLVSKEMNDTSLQLPSTTRSLSPKESNS
NEDFNVDGNETTLQRISKDYLKPNIGLVLLTVSYFFNSAMVVSTKVLENDPDDIANDR
QIKPLQILLVRMVITYIGTLIYMYINKSTISDVPFGKPEVRKWLVLRGCTGFFGVFGM
YYSLMYLTISDAVLITFLAPSLTIFLSWVILRERFTKVEALGSLISLLGVVLIVRPSF
LFGTPELTDSSSQIVESSDPKSRLIATLVGLWGVLGMSCVYIIIRYIGKRAHAIMSVS
YFSLITAIVSFIGINTIPSMKFQIPHSKKQWILFGNLGVSGFIFQLLLTMGIQRERAG
RGSLMTYTQLLYAVFWDVALYKHWPNIWSWIGMIIIISATLWVIRIRAANNETTAKDL
TPIIDDEENSIPLTEFDLSDSK"
gene 778001..778567
/gene="GFD1"
/locus_tag="YMR255W"
/db_xref="GeneID:855297"
mRNA 778001..778567
/gene="GFD1"
/locus_tag="YMR255W"
/product="Gfd1p"
/transcript_id="NM_001182762.1"
/db_xref="GI:296147375"
/db_xref="GeneID:855297"
CDS 778001..778567
/gene="GFD1"
/locus_tag="YMR255W"
/note="Coiled-coiled hypothetical protein; identified as a
high-copy suppressor of a dbp5 mutation; protein abundance
increases in response to DNA replication stress"
/codon_start=1
/product="Gfd1p"
/protein_id="NP_013982.1"
/db_xref="GI:6323911"
/db_xref="SGD:S000004868"
/db_xref="GeneID:855297"
/translation="MPLESIWADAPDEEPIKKQKPSHKRSNNNKKNNNSRWSNESSSN
NKKKDSVNKVKNNKGNHESKTKNKIKETLPREKKPPHSQGKISPVSESLAINPFSQKA
TEISPPPVSPSKMKTTKTQSKQDTASKMKLLKKKIEEQREILQKTHHKNQQQQVLMDF
LNDEGSSNWVDDDEEELILQRLKTSLKI"
gene complement(778945..779127)
/gene="COX7"
/locus_tag="YMR256C"
/db_xref="GeneID:855298"
mRNA complement(778945..779127)
/gene="COX7"
/locus_tag="YMR256C"
/product="cytochrome c oxidase subunit VII"
/transcript_id="NM_001182763.1"
/db_xref="GI:296147376"
/db_xref="GeneID:855298"
CDS complement(778945..779127)
/gene="COX7"
/locus_tag="YMR256C"
/EC_number="1.9.3.1"
/note="Subunit VII of cytochrome c oxidase, which is the
terminal member of the mitochondrial inner membrane
electron transport chain"
/codon_start=1
/product="cytochrome c oxidase subunit VII"
/protein_id="NP_013983.1"
/db_xref="GI:6323912"
/db_xref="SGD:S000004869"
/db_xref="GeneID:855298"
/translation="MANKVIQLQKIFQSSTKPLWWRHPRSALYLYPFYAIFAVAVVTP
LLYIPNAIRGIKAKKA"
gene complement(779629..782031)
/gene="PET111"
/locus_tag="YMR257C"
/db_xref="GeneID:855299"
mRNA complement(779629..782031)
/gene="PET111"
/locus_tag="YMR257C"
/product="Pet111p"
/transcript_id="NM_001182764.1"
/db_xref="GI:296147377"
/db_xref="GeneID:855299"
CDS complement(779629..782031)
/gene="PET111"
/locus_tag="YMR257C"
/note="Mitochondrial translational activator specific for
the COX2 mRNA; located in the mitochondrial inner
membrane"
/codon_start=1
/product="Pet111p"
/protein_id="NP_013984.1"
/db_xref="GI:6323913"
/db_xref="SGD:S000004870"
/db_xref="GeneID:855299"
/translation="MLQRRFISSSGIKRLLHRESNKVMHTVFFKVRYYSTELIKKKHK
EDIEDWVKAQLKDSSTISGVYESRNKLDWMDSITKSPSSLDILKNQYNIVKDKDFGIL
WKQKFESADPDILMTIISLSTNQKVLFSIQQLLILINSLHFLKRDYDIGQIYTTYEQF
TPLLASHTDKGTYGQFIEIMLVVQHNLHHFDVCETLFAEYIKYCKVKPQMISLGLNSF
IRSNNTQLAVEFYTQAITNPDTFPITEKQLFEFLRCMERYLDMSSMKHIFYLWLKVKC
GDEQSSSTNLPSFKTLAIIHRMLLRFSNTDELNDFLTNPVVLSTGYTSSVQFELIEFC
HSLYCIKGDRTKSIDDSILMERVDKFITRLNNNISTRKELYMSVVQAYVSTNNFENLK
VILEKIQRDNDISIDGSFHLCISRYFVNTNQFEGLFKYYRSVVKTTDGKTRLRPAFIQ
QLWSCAVNVYPMLAKEITNDLLVTLKRSQYSKCLTWVYTFLQENAHIHTRKINGGEDS
SLSGFNAVDFERFEEFKKKVSHNDVYGAELVISNSLKEGIAPQFSFLYSVLALCLRNS
LTGLARVVDVILRTRFRYIPLKVDILWLKWEIISNYRSFEKLSAEHLKELEFKLKEFE
RVHQKELSVQNYLQLTQICFHTRDFKYACYLISQARKNLDTSNNKQWMMYYMTSLKLA
SRMHESERFSRILKDWNCNHRASLITPGCIRQIKGFMKYFEKRPAYISTAASIDNKEI
KDRIDELVLRYVDYKYQGLENMRKLTLFLKEWFDEEISLLKLEQNERKMKLFEENKKE
EE"
gene complement(782620..784281)
/gene="ROY1"
/locus_tag="YMR258C"
/db_xref="GeneID:855300"
mRNA complement(782620..784281)
/gene="ROY1"
/locus_tag="YMR258C"
/product="Roy1p"
/transcript_id="NM_001182765.1"
/db_xref="GI:296147378"
/db_xref="GeneID:855300"
CDS complement(782620..784281)
/gene="ROY1"
/locus_tag="YMR258C"
/note="GTPase inhibitor with similarity to F-box proteins;
inhibits Ypt52p GTPase activity by preventing Ypt52p from
binding GTP; involved in regulating intracellular
trafficking; physically interacts with Skp1p"
/codon_start=1
/product="Roy1p"
/protein_id="NP_013985.1"
/db_xref="GI:6323914"
/db_xref="SGD:S000004871"
/db_xref="GeneID:855300"
/translation="MAFQDQDIFIVFSHASLFLNQNDLLSLSLTSKKMHDMIAIPRLY
SNIHITKNPVLRTNKWFLDGGKTYVSGYRSVLKTGDKNDIFLYDRIERLLETSHLKCI
KQLTIDEDLFHNREEGLQLLQRLVNEITDLDVIESLDIKDPTLFELCSAKYYRLSSLK
KRVVYGETGFDGIKLWQNFKSLKWQLPESLDLQNVIIPEVGVMLMKQLNGGELEIKDE
AYSSLRVFEYFDSLNLRFKNLRRLKLNHVHKQGDGSATSMRLSSRAFKDVVNLSNLKA
LELEFSCEVDDCECDDDFLQDITGNLVSLTSLGFIEKTFTKKGYHYMDEKWDLVVNKF
ILNLPNVSKDLRLLSIRHDPPLNGKGIDTVDGNLLRRKKLYEKVLPKLTSLETIIAPT
VLQSITSYEMYACDLLWNGCKCAFCSKYLPLFDKYIMNHQYFSTPDARYLDIIPIVFA
AYTGKSLAKRFDPQKNWDLDLLQYAPEDTTWNFHGFERIHHFASYECYFDESSFEPLA
TIISHFFYPYMNYLIKILPNLRQTMLSGIYFSVSPELHTYETIYD"
gene complement(784621..788883)
/gene="TRM732"
/locus_tag="YMR259C"
/db_xref="GeneID:855301"
mRNA complement(784621..788883)
/gene="TRM732"
/locus_tag="YMR259C"
/product="Trm732p"
/transcript_id="NM_001182766.1"
/db_xref="GI:296147379"
/db_xref="GeneID:855301"
CDS complement(784621..788883)
/gene="TRM732"
/locus_tag="YMR259C"
/note="Interacts with Trm7p for 2'-O-methylation of C32 of
substrate tRNAs; green fluorescent protein (GFP)-fusion
protein localizes to the cytoplasm; non-essential gene"
/codon_start=1
/product="Trm732p"
/protein_id="NP_013986.1"
/db_xref="GI:6323915"
/db_xref="SGD:S000004872"
/db_xref="GeneID:855301"
/translation="MTTDVQFSSQEIELFRVKEFLIANNPAKINNENKDAVLTQIEHD
FRYLIQYIKDGLPNLNESTRLIFPDTFSICLLRSHQIIASKKIDSQEFLSAVKEQLLT
EANANIIFEYVLDFWADGGAPLMNALRDLFSKLLNLLKITYPMSTLKDVLFNWMNEIL
EVPSTLRVQYYLIDALSSDFDLYYIIEKKPHFIDNSFSLMNSDLLANSVGKCIVSLLL
NIYEKHFKKNESFVQEWIQLWKSCALKYIHDKQYTKSINLYIMIPLFKNMPNSAFTLF
LECMSNKDPSLLLSLLKIGQELGIEEEPFCDNKYTTVDSVNKLIEQDEYKLQVFEILT
FSTKKSKPIRPFVFKTIKQYLYVFFVDTELERRNYFCSSMKHFIFRTRDCAYSLARDA
RKLKKAEKFPDEQREKLAQVEEARAFLVWLCNFIKYNLAPGTLYQANVTSLKLMHILI
KSGVDKSTPQKFLDNQNKREYPFSIPILQDVTFLRLLIDLLVSNYADVRELSKEMLFI
MISADESRGLFLDTLDANALKWTATSLLSDYEKGDAGATVYEFIFTVMGSQRSFIDQT
IDILAQMVQNLQNDSIGCAENSIGPHFAALSLILNKFNSEENHQDTSKIISKLINLVL
KSWEATRNVVCHDSAHGILPEKYANCGVPDQVIISHAFRAIKEASYLLETILKKYPLT
RDQLDSIGDLFIVQLSTIRHSGAFQAVLPGLKAFCIRCQLEFPAILEELLSKSVKSLK
SKTQHITRRSGGLPFLVTTVLSAEVTKGRPLLQKTFENLLLVARLPIPPHQDEFDLPQ
VNAINCINAIFVEPKLSVHCTSFVSEALELALLNFDCDIWALRNCSIMLFTSLQNRIF
GKVGRSVSAKLFFTKYSGLRQLLLNILNSSIAQYSGSERKSYQIESIFLVLNVLLRLR
PTAGYTGLKEFNVSVYECLSNENWKIRDMASRVLHMLSENFEEEIRKLLDLASIAKQN
QLHGHLLALQQLVPQYLSGTRDMELIQRILEKKRMLLLENKCFITKKAYLKLTCCILE
TCDIPDSILKDYISTLRNTFIAENNEYVVDGSKQLYLAQILDMLLKYEDSIYLDDICL
LGLYSPFYEAQLSTLQYMNTNFHWETTRNSEFLEQLQLLLRVPDLLPMAKALVVKILS
RKKNTLSLTTCTDLLKTNNSEDTKLAAVSSLSAKLSSQTFHQVWNLLQGFFADSCSKD
FRLASLECLTAYPESCKNSRILLQLYNFLWDDDSEIREKASFYLNKNFIQTADWEYNR
NTSVTALIFTKKFVDVFTSSEVVEELCLQLFQYLNEYDMFAAEESAKNCLFTIEKDNQ
FINELQKAMHILNMIKLTGRDISKCYKDQIHHLKSALLEHFNTEDFKDSPLGWCSNAE
IFSRITLLKELIQHYSPSDYENFINVLTKHSVHPLIISYSQL"
gene complement(789378..789839)
/gene="TIF11"
/locus_tag="YMR260C"
/db_xref="GeneID:855302"
mRNA complement(789378..789839)
/gene="TIF11"
/locus_tag="YMR260C"
/product="Tif11p"
/transcript_id="NM_001182767.1"
/db_xref="GI:296147380"
/db_xref="GeneID:855302"
CDS complement(789378..789839)
/gene="TIF11"
/locus_tag="YMR260C"
/note="Translation initiation factor eIF1A, essential
protein that forms a complex with Sui1p (eIF1) and the 40S
ribosomal subunit and scans for the start codon;
C-terminus associates with Fun12p (eIF5B); N terminus
interacts with eIF2 and eIF3"
/codon_start=1
/product="Tif11p"
/protein_id="NP_013987.1"
/db_xref="GI:6323916"
/db_xref="SGD:S000004873"
/db_xref="GeneID:855302"
/translation="MGKKNTKGGKKGRRGKNDSDGPKRELIYKEEGQEYAQITKMLGN
GRVEASCFDGNKRMAHIRGKLRKKVWMGQGDIILVSLRDFQDDQCDVVHKYNLDEART
LKNQGELPENAKINETDNFGFESDEDVNFEFGNADEDDEEGEDEELDIDDI"
gene complement(790205..793369)
/gene="TPS3"
/locus_tag="YMR261C"
/db_xref="GeneID:855303"
mRNA complement(790205..793369)
/gene="TPS3"
/locus_tag="YMR261C"
/product="Tps3p"
/transcript_id="NM_001182768.1"
/db_xref="GI:296147381"
/db_xref="GeneID:855303"
CDS complement(790205..793369)
/gene="TPS3"
/locus_tag="YMR261C"
/note="Regulatory subunit of trehalose-6-phosphate
synthase/phosphatase complex, which synthesizes the
storage carbohydrate trehalose; expression is induced by
stress conditions and repressed by the Ras-cAMP pathway"
/codon_start=1
/product="Tps3p"
/protein_id="NP_013988.1"
/db_xref="GI:6323917"
/db_xref="SGD:S000004874"
/db_xref="GeneID:855303"
/translation="MTIIVASLFLPYTPQFEADVTNSDTAKLVESSMIKVDCNNQELS
NNKQERSSSVTSASSHYIGLPQEAQINGEPLQRANVGSPATGVNYHNEMEMLSSEQFL
EELTANATHAANSGIPPANNPVSSGSTAQRPSVEEFFSAPSARVCSPSQEASASSISA
SRSSAHHNDLSSSLMKNPNLSFDSHPPRVRSSSKSAVITPVSKSVPDVDPAVVDVAKV
REEFQQQASLPSMKRVSGSTAGDSSIASSSSNLRYSQQFQDNFIEDTDSEDDIDSDLE
TDATKKYNVPKFGGYSNNAKLRASLMRNSYELFKHLPWTIVDSDKGNGSLKNAVNIAV
AEKTVKEPVSWVGTMGIPTDELPHEVCHKISKKLEQDFSSFPVVTDDITFKGAYKNYA
KQILWPTLHYQIPDNPNSKAFEDHSWDYYQKVNQKFSDRIVSVYKPGDTIWIHDYHLM
LVPQMVREKLPKAKIGFFLHVSFPSSEVFRCLANRERILEGIIGANFVGFQTKEYKRH
FLQTCNRLLAADVSNDEVKYHCNIVSVMYAPIGIDYYHLTSQLRNGSVLEWRQLIKER
WRNKKLIVCRDQFDRIRGLQKKMLAYERFLIENPEYIEKVVLIQICIGKSSDPEYERQ
IMVVVDRINSLSSNISISQPVVFLHQDLDFAQYLALNCEADVFLVDALREGMNLTCHE
FIVSSFEKNAPLLLSEFTGSSSVLKEGAILINPWDINHVAQSIKRSLEMSPEEKRRRW
KKLFKSVIEHDSDNWITKCFEYINNAWESNQETSTVFNLAPEKFCADYKASKKHLFIF
KISEPPTSRMLSLLSELSSNNIVYVLSSFTKNTFESLYNGVLNIGLIAENGAYVRVNG
SWYNIVEELDWMKEVAKIFDEKVERLPGSYYKIADSMIRFHTENADDQDRVPTVIGEA
ITHINTLFDDRDIHAYVHKDIVFVQQTGLALAAAEFLMKFYNSGVSPTDNSRISLSRT
SSSMSVGNNKKHFQNQVDFVCVSGSTSPIIEPLFKLVKQEVEKNNLKFGYTILYGSSR
STYAKEHINGVNELFTILHDLTAA"
gene 793726..794667
/locus_tag="YMR262W"
/db_xref="GeneID:855304"
mRNA 793726..794667
/locus_tag="YMR262W"
/product="hypothetical protein"
/transcript_id="NM_001182769.2"
/db_xref="GI:330443682"
/db_xref="GeneID:855304"
CDS 793726..794667
/locus_tag="YMR262W"
/note="hypothetical protein; interacts weakly with Knr4p;
YMR262W is not an essential gene"
/codon_start=1
/product="hypothetical protein"
/protein_id="NP_013989.2"
/db_xref="GI:330443683"
/db_xref="SGD:S000004875"
/db_xref="GeneID:855304"
/translation="MNKLVDAHCHVITDPDNTFCGDDGGSQGTLRCVMSSNPYDWNNL
KKLAGRSTSKNDICVGFGVHPWYSHLFYVGSRRDKVSHYQDVLEYKNEEQFDSLVQVL
PEPLDLEEYIKREFNDTLVSVIGEIGLDKLFRLPANGFYMQNEKARLTTVKVKLSHQE
TVFRRFCRLARHTSKPISIHDVKCHGKLNDICNEELLTYHSVKICLHSYTGSKETLLG
QWLKKFPPDRIFVSLSKWINFKDPEEGDALVRSLPSTCILTETDYPIDNPDPSYQKAL
TEQLQYLNAQIARAWDETLDASQAALRVYENFQKFIK"
gene 794919..795524
/gene="SAP30"
/locus_tag="YMR263W"
/db_xref="GeneID:855305"
mRNA 794919..795524
/gene="SAP30"
/locus_tag="YMR263W"
/product="Sap30p"
/transcript_id="NM_001182770.1"
/db_xref="GI:296147383"
/db_xref="GeneID:855305"
CDS 794919..795524
/gene="SAP30"
/locus_tag="YMR263W"
/note="Subunit of a histone deacetylase complex, along
with Rpd3p and Sin3p, that is involved in silencing at
telomeres, rDNA, and silent mating-type loci; involved in
telomere maintenance"
/codon_start=1
/product="Sap30p"
/protein_id="NP_013990.1"
/db_xref="GI:6323919"
/db_xref="SGD:S000004876"
/db_xref="GeneID:855305"
/translation="MARPVNTNAETESRGRPTQGGGYASNNNGSCNNNNGSNNNNNNN
NNNNNNSNNSNNNNGPTSSGRTNGKQRLTAAQQQYIKNLIETHITDNHPDLRPKSHPM
DFEEYTDAFLRRYKDHFQLDVPDNLTLQGYLLGSKLGAKTYSYKRNTQGQHDKRIHKR
DLANVVRRHFDEHSIKETDCIPQFIYKVKNQKKKFKMEFRG"
gene 795805..796416
/gene="CUE1"
/locus_tag="YMR264W"
/gene_synonym="KIS4"
/db_xref="GeneID:855306"
mRNA 795805..796416
/gene="CUE1"
/locus_tag="YMR264W"
/gene_synonym="KIS4"
/product="Cue1p"
/transcript_id="NM_001182771.1"
/db_xref="GI:296147384"
/db_xref="GeneID:855306"
CDS 795805..796416
/gene="CUE1"
/locus_tag="YMR264W"
/gene_synonym="KIS4"
/note="Endoplasmic reticulum membrane protein that
recruits the ubiquitin-conjugating enzyme Ubc7p to the ER
where it functions in protein degradation; contains a CUE
domain that binds ubiquitin to facilitate intramolecular
monoubiquitination"
/codon_start=1
/product="Cue1p"
/protein_id="NP_013991.1"
/db_xref="GI:6323920"
/db_xref="SGD:S000004877"
/db_xref="GeneID:855306"
/translation="MEDSRLLITLILVFGVIFLKKFFQSNQHPSAQRLSATGVNAHGR
PQGSTQNALRRTGRVNGGHPVTTQMVETVQNLAPNLHPEQIRYSLENTGSVEETVERY
LRGDEFSFPPGFEPSRAPMGANAAVDNNAAGGGEFNDPRKKNMICAENLLDKFHVDLN
EDMSNLSFKDLDIEERKRLLVWQARKNLETKLQSDKDLQSLLT"
gene complement(796540..797925)
/locus_tag="YMR265C"
/db_xref="GeneID:855307"
mRNA complement(796540..797925)
/locus_tag="YMR265C"
/product="hypothetical protein"
/transcript_id="NM_001182772.1"
/db_xref="GI:296147385"
/db_xref="GeneID:855307"
CDS complement(796540..797925)
/locus_tag="YMR265C"
/codon_start=1
/product="hypothetical protein"
/protein_id="NP_013992.1"
/db_xref="GI:6323921"
/db_xref="SGD:S000004878"
/db_xref="GeneID:855307"
/translation="MEEFEEFRRKGEMSSRCGNHRVLRKWNSCACELAVPFEVPEHAI
TKLHIYDFDNTLFATPGPTEQLYTRELLNLLTSSTLPNGGWWNEPGFLQAAIEISKTK
PRRYSWNADIVKLAEESYSAKDTISIVLTGREESKFHKLIEHALQTARSHWKCSENEF
RFNAVCLKKRAISEYTSKYKKELMRDFLEYYPSLRELSIYDDRIHQIDAFKSFFHSLD
LPRLKWSAIPVRPFTKSLPREQELEMVMDMVRKNNSQALSTSQKFDLRRTPRQIGYIL
CTASHRLLSIEVIKYLKRRKGRRTFRPKLYEHPLYIPCAEPGKDIPALEIAKVWSNND
TRTFDSEKKVQHISQIFYLEQPGKCIVHFQVTDLAVIASAHHNRRKPLEVYFKATPEP
NRYTFTLFPEYIVTGHFYKRDRIEDLEVVTERLINCKEDIHWVPLDNTIPIKAFFGRF
AKLAAIPCSNA"
gene 798518..801379
/gene="RSN1"
/locus_tag="YMR266W"
/db_xref="GeneID:855308"
mRNA 798518..801379
/gene="RSN1"
/locus_tag="YMR266W"
/product="Rsn1p"
/transcript_id="NM_001182773.1"
/db_xref="GI:296147386"
/db_xref="GeneID:855308"
CDS 798518..801379
/gene="RSN1"
/locus_tag="YMR266W"
/note="Membrane hypothetical protein; overexpression
suppresses NaCl sensitivity of sro7 mutant cells by
restoring sodium pump (Ena1p) localization to the plasma
membrane"
/codon_start=1
/product="Rsn1p"
/protein_id="NP_013993.1"
/db_xref="GI:6323922"
/db_xref="SGD:S000004879"
/db_xref="GeneID:855308"
/translation="MNSTNSTNSTTTATSTNTSTQQVVTSLVSNGTIFGVFVIAFLIL
RIKLKRIYEPKSSFNLINEEKKPEPLPQGVWQWLKPLLKKSDNFVIQQAGLDGYFFLR
YLFIIAIYCAVSMSYIFPILLSINASNGNHESGLNQLAYQNVKHRGRYFAHVFCGWIF
FWGFLYIIYRELYFYTSMKQAVLASPRYAKKLSSRTVLFQTVPKQYLSEEEFSKLFDG
VKRVWIARGSGSIEAMVKARDNMAIQLEGAETKYLKAALKKIKKLNKKSPQLSVSDNI
AEYVPDKKRPHHKINKVAKFFFGKKVDTISYIKEELPKLNQKVKALQEDHENSSPFNS
VFVEFESQYQAQVAAQITTYHAPLFMTPVYIGIEPSDVVWFNLRMFWWERLGREVSAV
SAIVALVILWAFPVAFVGMISNITSLTNEVKWLKFIYKLPKQLLGLLTSLAPTVALAV
LMSFLPKFIRGMAITQGAPSKQNVEYFTQQAYFAFQVIQVFLVTTLSSAATSTVTEIV
KEPTKAMDLLASNLPKASNFFMSYVILQGLSISSGALLQIVPLILFYVLGAFLDGTVR
KKWNRFCGLSSMQWGTAFPVYTNLAVITFSYSIISPLILLFAAVAFFLLYIAYLYNLT
YVYQESPDARGIYYPRALFQTIVGIYIGQICLLGLFAVGKGWGPIVLQVIGICVTVLI
HLHLSAAFDHLSKVIPVDTMKPLDGVSDTPSFKNIYKGIESTKVKKNTFGANIDMDGI
KELPEFPIKKYHKRSESVTEQQVENSIFSENTFEYQFNPANEANADGHAINAENLIED
VPLLADGDTMKIPPAPWWKRFLKPHIYYSYKAVKSRLPEIYGLVDPDERVNDFDISHA
YDYPAVSAQCPELWIPRDPFGFSKLLISDVSGVVEMNDENATIDENLKFTLRDVPPPY
NDVKDEANGEANGEFDTASKENNPFADPKYKEEESRSAV"
gene 801772..802704
/gene="PPA2"
/locus_tag="YMR267W"
/gene_synonym="IPP2"
/db_xref="GeneID:855309"
mRNA 801772..802704
/gene="PPA2"
/locus_tag="YMR267W"
/gene_synonym="IPP2"
/product="Ppa2p"
/transcript_id="NM_001182774.1"
/db_xref="GI:296147387"
/db_xref="GeneID:855309"
CDS 801772..802704
/gene="PPA2"
/locus_tag="YMR267W"
/gene_synonym="IPP2"
/EC_number="3.6.1.1"
/note="Mitochondrial inorganic pyrophosphatase, required
for mitochondrial function and possibly involved in energy
generation from inorganic pyrophosphate"
/codon_start=1
/product="Ppa2p"
/protein_id="NP_013994.1"
/db_xref="GI:6323923"
/db_xref="SGD:S000004880"
/db_xref="GeneID:855309"
/translation="MNLLRMNALTSKARSIERLKQTLNILSIRNHRQFSTIQQGSKYT
LGFKKYLTLLNGEVGSFFHDVPLDLNEHEKTVNMIVEVPRWTTGKFEISKELRFNPIV
QDTKNGKLRFVNNIFPYHGYIHNYGAIPQTWEDPTIEHKLGKCDVALKGDNDPLDCCE
IGSDVLEMGSIKKVKVLGSLALIDDGELDWKVIVIDVNDPLSSKIDDLEKIEEYFPGI
LDTTREWFRKYKVPAGKPLNSFAFHEQYQNSNKTIQTIKKCHNSWKNLISGSLQEKYD
NLPNTERAGNGVTLEDSVKPPSQIPPEVQKWYYV"
gene complement(802888..804222)
/gene="PRP24"
/locus_tag="YMR268C"
/db_xref="GeneID:855310"
mRNA complement(802888..804222)
/gene="PRP24"
/locus_tag="YMR268C"
/product="Prp24p"
/transcript_id="NM_001182775.1"
/db_xref="GI:296147388"
/db_xref="GeneID:855310"
CDS complement(802888..804222)
/gene="PRP24"
/locus_tag="YMR268C"
/note="Splicing factor that reanneals U4 and U6 snRNPs
during spliceosome recycling"
/codon_start=1
/product="Prp24p"
/protein_id="NP_013995.1"
/db_xref="GI:6323924"
/db_xref="SGD:S000004881"
/db_xref="GeneID:855310"
/translation="MEYGHHARPDSKRPLDEGSPAAAGLTSKKANEALTRNRELTTVL
VKNLPKSYNQNKVYKYFKHCGPIIHVDVADSLKKNFRFARIEFARYDGALAAITKTHK
VVGQNEIIVSHLTECTLWMTNFPPSYTQRNIRDLLQDINVVALSIRLPSLRFNTSRRF
AYIDVTSKEDARYCVEKLNGLKIEGYTLVTKVSNPLEKSKRTDSATLEGREIMIRNLS
TELLDENLLRESFEGFGSIEKINIPAGQKEHSFNNCCAFMVFENKDSAERALQMNRSL
LGNREISVSLADKKPFLERNEVKRLLASRNSKELETLICLFPLSDKVSPSLICQFLQE
EIHINEKDIRKILLVSDFNGAIIIFRDSKFAAKMLMILNGSQFQGKVIRSGTINDMKR
YYNNQQNHSMKHVKPSCINMMEKGPNLQVKKKIPDKQEQMSNDDFRKMFLGE"
gene 804456..805091
/gene="TMA23"
/locus_tag="YMR269W"
/gene_synonym="YMR268W-A"
/db_xref="GeneID:855311"
mRNA 804456..805091
/gene="TMA23"
/locus_tag="YMR269W"
/gene_synonym="YMR268W-A"
/product="Tma23p"
/transcript_id="NM_001182776.1"
/db_xref="GI:296147389"
/db_xref="GeneID:855311"
CDS 804456..805091
/gene="TMA23"
/locus_tag="YMR269W"
/gene_synonym="YMR268W-A"
/note="Nucleolar protein implicated in ribosome
biogenesis; deletion extends chronological lifespan"
/codon_start=1
/product="Tma23p"
/protein_id="NP_013996.2"
/db_xref="GI:44829555"
/db_xref="SGD:S000004882"
/db_xref="GeneID:855311"
/translation="MDSKEYLISYGWKEGEAFREGGLKRPILVKHKRDKKGLGNAPGG
NDGEAWWERLFDGHLKNLDVSTDSNNGSIKFTQNEAVATAVSKSSSPLYRWFVKGEGL
KGTITNLGKKEEASFVVSSASSSKGKKRRRRDEDDNKVKRKKLKKDKKTSNDSESKKK
KKKKSKKESKKGKKSKHSSDEGDKSKHKKSKKSKKHKKEESSARRDRKEHI"
rep_origin 805117..805338
/note="ARS1329;
Autonomously Replicating Sequence"
/db_xref="SGD:S000118379"
gene complement(805326..806423)
/gene="RRN9"
/locus_tag="YMR270C"
/db_xref="GeneID:855312"
mRNA complement(805326..806423)
/gene="RRN9"
/locus_tag="YMR270C"
/product="Rrn9p"
/transcript_id="NM_001182777.1"
/db_xref="GI:296147390"
/db_xref="GeneID:855312"
CDS complement(805326..806423)
/gene="RRN9"
/locus_tag="YMR270C"
/note="Protein involved in promoting high level
transcription of rDNA, subunit of UAF (upstream activation
factor) for RNA polymerase I"
/codon_start=1
/product="Rrn9p"
/protein_id="NP_013997.1"
/db_xref="GI:6323926"
/db_xref="SGD:S000004883"
/db_xref="GeneID:855312"
/translation="MSDLDEESQIETQIDAPIEDIIRGSELTTTTADKETLKSANELL
DSLEHSHRVDLSLHLYSAYLLKRLLYKANEKKHFYEVNQFVKTQIKDNWTSWPNPNTI
IDPSVDKLYEDIPEGIANVSVQPGEISNRALMHASDMMRVELDAQWQKFLSKSALDHD
VTLDVDELNIPNEISRNILVKLDSLFEGLHDKIAKENEFDVRQDKHSNNIRANQIDDE
PMQANRRIKYTYHDLVSRGCEMNEDMTDIYMKSLELYNDIPEKYKKRKFRLPKQILKK
YHQPKKTSSYLKELLSKTREDFIPVEKLLKDKRLTSKDKSKLQRLNREETEDALNKRT
FFQVKGYLEDENEISDYELDDCLIELPNGNI"
gene complement(806865..807548)
/gene="URA10"
/locus_tag="YMR271C"
/db_xref="GeneID:855313"
mRNA complement(806865..807548)
/gene="URA10"
/locus_tag="YMR271C"
/product="orotate phosphoribosyltransferase URA10"
/transcript_id="NM_001182778.1"
/db_xref="GI:296147391"
/db_xref="GeneID:855313"
CDS complement(806865..807548)
/gene="URA10"
/locus_tag="YMR271C"
/EC_number="2.4.2.10"
/note="Minor orotate phosphoribosyltransferase (OPRTase)
isozyme that catalyzes the fifth enzymatic step in the de
novo biosynthesis of pyrimidines, converting orotate into
orotidine-5'-phosphate; major OPRTase encoded by URA5"
/codon_start=1
/product="orotate phosphoribosyltransferase URA10"
/protein_id="NP_013998.1"
/db_xref="GI:6323927"
/db_xref="SGD:S000004884"
/db_xref="GeneID:855313"
/translation="MSASTTSLEEYQKTFLELGLECKALRFGSFKLNSGRQSPYFFNL
SLFNSGKLLANLATAYATAIIQSELKFDVIFGPAYKGIPLAAIVCVKLAEIGGTKFQG
IQYAFNRKKVKDHGEGGIIVGASLEDKRVLIIDDVMTAGTAINEAFEIISIAQGRVVG
CIVALDRQEVIHESDPERTSATQSVSKRYNVPVLSIVSLTQVVQFMGNRLSPEQKSAI
ENYRKAYGI"
gene complement(808246..808317)
/gene="CDC65"
/locus_tag="tQ(CUG)M"
/db_xref="GeneID:855314"
tRNA complement(808246..808317)
/gene="CDC65"
/locus_tag="tQ(CUG)M"
/product="tRNA-Gln"
/note="Glutamine tRNA (tRNA-Gln), predicted by tRNAscan-SE
analysis; can mutate to cause constitutive pseudohyphal
growth in homozygous diploids"
/db_xref="SGD:S000006690"
/db_xref="GeneID:855314"
LTR complement(808537..808906)
/note="Ty4 LTR"
/db_xref="SGD:S000007118"
LTR 809000..809233
/note="Ty1 LTR"
/db_xref="SGD:S000007126"
gene complement(809623..810777)
/gene="SCS7"
/locus_tag="YMR272C"
/gene_synonym="FAH1"
/db_xref="GeneID:855315"
mRNA complement(809623..810777)
/gene="SCS7"
/locus_tag="YMR272C"
/gene_synonym="FAH1"
/product="fatty acid alpha-hydroxylase"
/transcript_id="NM_001182779.1"
/db_xref="GI:296147392"
/db_xref="GeneID:855315"
CDS complement(809623..810777)
/gene="SCS7"
/locus_tag="YMR272C"
/gene_synonym="FAH1"
/EC_number="1.-.-.-"
/note="Sphingolipid alpha-hydroxylase, functions in the
alpha-hydroxylation of sphingolipid-associated very long
chain fatty acids, has both cytochrome b5-like and
hydroxylase/desaturase domains, not essential for growth"
/codon_start=1
/product="fatty acid alpha-hydroxylase"
/protein_id="NP_013999.1"
/db_xref="GI:6323928"
/db_xref="SGD:S000004885"
/db_xref="GeneID:855315"
/translation="MSTNTSKTLELFSKKTVQEHNTANDCWVTYQNRKIYDVTRFLSE
HPGGDESILDYAGKDITEIMKDSDVHEHSDSAYEILEDEYLIGYLATDEEAARLLTNK
NHKVEVQLSADGTEFDSTTFVKELPAEEKLSIATDYSNDYKKHKFLDLNRPLLMQILR
SDFKKDFYVDQIHRPRHYGKGSAPLFGNFLEPLTKTAWWVVPVAWLPVVVYHMGVALK
NMNQLFACFLFCVGVFVWTLIEYGLHRFLFHFDDWLPESNIAFATHFLLHGCHHYLPM
DKYRLVMPPTLFVILCAPFYKLVFALLPLYWAYAGFAGGLFGYVCYDECHFFLHHSKL
PPFMRKLKKYHLEHHYKNYQLGFGVTSWFWDEVFGTYLGPDAPLSKMKYE"
gene 811089..811196
/locus_tag="YMR272W-B"
/db_xref="GeneID:1466507"
mRNA 811089..811196
/locus_tag="YMR272W-B"
/product="hypothetical protein"
/transcript_id="NM_001184617.1"
/db_xref="GI:296147393"
/db_xref="GeneID:1466507"
CDS 811089..811196
/locus_tag="YMR272W-B"
/note="Identified by gene-trapping, microarray-based
expression analysis, and genome-wide homology searching"
/codon_start=1
/product="hypothetical protein"
/protein_id="NP_878149.1"
/db_xref="GI:33438861"
/db_xref="SGD:S000028696"
/db_xref="GeneID:1466507"
/translation="MRSLVFVQLSLLSWEIFCGERSFVSMKAIFSCMYV"
gene complement(811233..813980)
/gene="ZDS1"
/locus_tag="YMR273C"
/gene_synonym="CES1; CKM1; NRC1; OSS1"
/db_xref="GeneID:855316"
mRNA complement(811233..813980)
/gene="ZDS1"
/locus_tag="YMR273C"
/gene_synonym="CES1; CKM1; NRC1; OSS1"
/product="Zds1p"
/transcript_id="NM_001182780.1"
/db_xref="GI:296147394"
/db_xref="GeneID:855316"
CDS complement(811233..813980)
/gene="ZDS1"
/locus_tag="YMR273C"
/gene_synonym="CES1; CKM1; NRC1; OSS1"
/note="Protein with a role in regulating Swe1p-dependent
polarized growth; involved in maintaining Cdc55p in the
cytoplasm where it promotes mitotic entry; involved in
mitotic exit through Cdc14p regulation; interacts with
silencing proteins at the telomere; has a role in Bcy1p
localization; implicated in mRNA nuclear export"
/codon_start=1
/product="Zds1p"
/protein_id="NP_014000.1"
/db_xref="GI:6323929"
/db_xref="SGD:S000004886"
/db_xref="GeneID:855316"
/translation="MSNRDNESMLRTTSSDKAIASQRDKRKSEVLIAAQSLDNEIRSV
KNLKRLSIGSMDLLIDPELDIKFGGESSGRRSWSGTTSSSASMPSDTTTVNNTRYSDP
TPLENLHGRGNSGIESSNKTKQGNYLGIKKGVHSPSRKLNANVLKKNLLWVPANQHPN
VKPDNFLELVQDTLQNIQLSDNGEDNDGNSNENNDIEDNGEDKESQSYENKENNTINL
NRGLSRHGNASLIRRPSTLRRSYTEFDDNEDDDNKGDSASETVNKVEERISKIKERPV
SLRDITEELTKISNSAGLTDNDAITLARTLSMAGSYSDKKDQPQPEGHYDEGDIGFST
SQANTLDDGEFASNMPINNTMTWPERSSLRRSRFNTYRIRSQEQEKEVEQSVDEMKND
DEERLKLTKNTIKVEIDPHKSPFRQQDEDSENMSSPGSIGDFQDIYNHYRQSSGEWEQ
EMGIEKEAEEVPVKVRNDTVEQDLELREGTTDMVKPSATDDNKETKRHRRRNGWTWLN
NKMSREDDNEENQGDDENEENVDSQRMELDNSKKHYISLFNGGEKTEVSNKEEMNNSS
TSTATSQTRQKIEKTFANLFRRKPHHKHDASSSPSSSPSSSPSIPNNDAVHVRVRKSK
KLGNKSGREPVEPIVLRNRPRPHRHHHSRHGSQKISVKTLKDSQPQQQIPLQPQLEGA
IEIEKKEESDSESLPQLQPAVSVSSTKSNSRDREEEEAKKKNKKRSNTTEISNQQHSK
HVQKENTDEQKAQLQAPAQEQVQTSVPVQASAPVQNSAPVQTSAPVEASAQTQAPAAP
PLKHTSILPPRKLTFADVKKPDKPNSPVQFTDSAFGFPLPLLTVSTVIMFDHRLPINV
ERAIYRLSHLKLSNSKRGLREQVLLSNFMYAYLNLVNHTLYMEQVAHDKEQQQQQQQQ
P"
gene complement(814364..815311)
/gene="RCE1"
/locus_tag="YMR274C"
/db_xref="GeneID:855317"
mRNA complement(814364..815311)
/gene="RCE1"
/locus_tag="YMR274C"
/product="Rce1p"
/transcript_id="NM_001182781.1"
/db_xref="GI:296147395"
/db_xref="GeneID:855317"
CDS complement(814364..815311)
/gene="RCE1"
/locus_tag="YMR274C"
/EC_number="3.4.-.-"
/note="Type II CAAX prenyl protease involved in the
proteolysis and maturation of Ras and the a-factor mating
pheromone"
/codon_start=1
/product="Rce1p"
/protein_id="NP_014001.1"
/db_xref="GI:6323930"
/db_xref="SGD:S000004887"
/db_xref="GeneID:855317"
/translation="MLQFSTFLVLLYISISYVLPLYATSQPEGSKRDNPRTIKSRMQK
LTIMLISNLFLVPFLQSQLSSTTSHISFKDAFLGLGIIPGYYAALPNPWQFSQFVKDL
TKCVAMLLTLYCGPVLDFVLYHLLNPKSSILEDFYHEFLNIWSFRNFIFAPITEEIFY
TSMLLTTYLNLIPHSQLSYQQLFWQPSLFFGLAHAHHAYEQLQEGSMTTVSILLTTCF
QILYTTLFGGLTKFVFVRTGGNLWCCIILHALCNIMGFPGPSRLNLHFTVVDKKAGRI
SKLVSIWNKCYFALLVLGLISLKDTLQTLVGTPGYRITL"
rep_origin 815342..815567
/note="ARS1330;
Autonomously Replicating Sequence"
/db_xref="SGD:S000118380"
gene complement(815651..818581)
/gene="BUL1"
/locus_tag="YMR275C"
/gene_synonym="DAG1; RDS1; SMM2"
/db_xref="GeneID:855318"
mRNA complement(815651..818581)
/gene="BUL1"
/locus_tag="YMR275C"
/gene_synonym="DAG1; RDS1; SMM2"
/product="ubiquitin-ubiquitin ligase BUL1"
/transcript_id="NM_001182782.1"
/db_xref="GI:296147396"
/db_xref="GeneID:855318"
CDS complement(815651..818581)
/gene="BUL1"
/locus_tag="YMR275C"
/gene_synonym="DAG1; RDS1; SMM2"
/note="Ubiquitin-binding component of the Rsp5p
E3-ubiquitin ligase complex; disruption causes
temperature-sensitive growth, overexpression causes
missorting of amino acid permeases; BUL1 has a paralog,
BUL2, that arose from the whole genome duplication"
/codon_start=1
/product="ubiquitin-ubiquitin ligase BUL1"
/protein_id="NP_014002.1"
/db_xref="GI:6323931"
/db_xref="SGD:S000004888"
/db_xref="GeneID:855318"
/translation="MAKDLNDSGFPPKRKPLLRPQRSDFTANSSTTMNVNANTRGRGR
QKQEGGKGSSRSPSLHSPKSWIRSASATGILGLRRPELAHSHSHAPSTGTPAGGNRSP
LRRSTANATPVETGRSLTDGDINNVVDVLPSFEMYNTLHRHIPQGNVDPDRHDFPPSY
QEANNSTATGAAGSSADLSHQSLSTDALGATRSSSTSNLENLIPLRTEHHSIAAHQST
AVDEDSLDIPPILDDLNDTDNIFIDKLYTLPKMSTPIEITIKTTKHAPIPHVKPEEES
ILKEYTSGDLIHGFITIENKSQANLKFEMFYVTLESYISIIDKVKSKRTIKRFLRMVD
LSASWSYSKIALGSGVDFIPADVDYDGSVFGLNNSRVLEPGVKYKKFFIFKLPLQLLD
VTCKQEHFSHCLLPPSFGIDKYRNNCKYSGIKVNRVLGCGHLGTKGSPILTNDMSDDN
LSINYTIDARIVGKDQKASKLYIMKEREYNLRVIPFGFDANVVGERTTMSQLNDITKL
VQERLDALRKIFQRLEKKEPITNRDIHGADLSGTIDDSIESDSQEILQRKLDQLHIKN
RNNYLVNYNDLKLGHDLDNGRSGNSGHNTDTSRAWGPFVESELKYKLKNKSNSSSFLN
FSHFLNSSSSSMSSSSNAGKNNHDLTGNKERTGLILVKAKIPKQGLPYWAPSLLRKTN
VFESKSKHDQENWVRLSELIPEDVKKPLEKLDLQLTCIESDNSLPHDPPEIQSITTEL
ICITAKSDNSIPIKLNSELLMNKEKLTSIKALYDDFHSKICEYETKFNKNFLELNELY
NMNRGDRRPKELKFTDFITSQLFNDIESICNLKVSVHNLSNIFKKQVSTLKQHSKHAL
SEDSISHTGNGSSSSPSSASLTPVTSSSKSSLFLPSGSSSTSLKFTDQIVHKWVRIAP
LQYKRDINVNLEFNKDIKETLIPSFESCLCCRFYCVRVMIKFENHLGVAKIDIPISVR
QVTK"
gene 818827..819948
/gene="DSK2"
/locus_tag="YMR276W"
/db_xref="GeneID:855319"
mRNA 818827..819948
/gene="DSK2"
/locus_tag="YMR276W"
/product="Dsk2p"
/transcript_id="NM_001182783.1"
/db_xref="GI:296147397"
/db_xref="GeneID:855319"
CDS 818827..819948
/gene="DSK2"
/locus_tag="YMR276W"
/note="Nuclear-enriched ubiquitin-like
polyubiquitin-binding protein; required for spindle pole
body (SPB) duplication and for transit through the G2/M
phase of the cell cycle; involved in proteolysis;
interacts with the proteasome; protein abundance increases
in response to DNA replication stress"
/codon_start=1
/product="Dsk2p"
/protein_id="NP_014003.1"
/db_xref="GI:6323932"
/db_xref="SGD:S000004889"
/db_xref="GeneID:855319"
/translation="MSLNIHIKSGQDKWEVNVAPESTVLQFKEAINKANGIPVANQRL
IYSGKILKDDQTVESYHIQDGHSVHLVKSQPKPQTASAAGANNATATGAAAGTGATPN
MSSGQSAGFNPLADLTSARYAGYLNMPSADMFGPDGGALNNDSNNQDELLRMMENPIF
QSQMNEMLSNPQMLDFMIQSNPQLQAMGPQARQMLQSPMFRQMLTNPDMIRQSMQFAR
MMDPNAGMGSAGGAASAFPAPGGDAPEEGSNTNTTSSSNTGNNAGTNAGTNAGANTAA
NPFASLLNPALNPFANAGNAASTGMPAFDPALLASMFQPPVQASQAEDTRPPEERYEH
QLRQLNDMGFFDFDRNVAALRRSGGSVQGALDSLLNGDV"
gene 820256..822454
/gene="FCP1"
/locus_tag="YMR277W"
/db_xref="GeneID:855320"
mRNA 820256..822454
/gene="FCP1"
/locus_tag="YMR277W"
/product="Fcp1p"
/transcript_id="NM_001182784.1"
/db_xref="GI:296147398"
/db_xref="GeneID:855320"
CDS 820256..822454
/gene="FCP1"
/locus_tag="YMR277W"
/EC_number="3.1.3.16"
/note="Carboxy-terminal domain (CTD) phosphatase,
essential for dephosphorylation of the repeated C-terminal
domain of the RNA polymerase II large subunit (Rpo21p)"
/codon_start=1
/product="Fcp1p"
/protein_id="NP_014004.1"
/db_xref="GI:6323933"
/db_xref="SGD:S000004890"
/db_xref="GeneID:855320"
/translation="MTTQIRSPQGLPYPIQIDKLIPSVGSYLHEGDRLLVYKFWYLVE
RASDTGDDDNEHDVSPGGSAGSNGVSPPTKQLRESIEFFESPYEGDLISWNVDVGDEV
ATANQVICEIKRPCNHDIVYGGLCTQCGKEVSADAFDGVPLDVVGDVDLQISETEAIR
TGKALKEHLRRDKKLILVVDLDQTIIHCGVDPTIAEWKNDPNNPNFETLRDVKSFTLD
EELVLPLMYMNDDGSMLRPPPVRKCWYYVKVRPGLKEFFAKVAPLFEMHIYTMATRAY
ALQIAKIVDPTGELFGDRILSRDENGSLTTKSLAKLFPTDQSMVVVIDDRGDVWNWCP
NLIKVVPYNFFVGVGDINSNFLPKQSTGMLQLGRKTRQKSQESQELLTDIMDNEKKLQ
EKIDKEVKRQEEKLNHQLATAEEPPANESKEELTKKLEYSASLEVQQQNRPLAKLQKH
LHDQKLLVDDDDELYYLMGTLSNIHKTYYDMLSQQNEPEPNLMEIIPSLKQKVFQNCY
FVFSGLIPLGTDIQRSDIVIWTSTFGATSTPDIDYLTTHLITKNPSTYKARLAKKFNP
QIKIVHPDWIFECLVNWKKVDEKPYTLIVDSPISDEELQNFQTQLQKRQEYLEETQEQ
QHMLTSQENLNLFAAGTSWLNNDDDEDIPDTASDDDEDDDHDDESDDENNSEGIDRKR
SIEDNHDDTSQKKTKAEPSQDGPVQHKGEGDDNEDSDSQLEEELMDMLDD"
gene 822763..824631
/gene="PGM3"
/locus_tag="YMR278W"
/db_xref="GeneID:855321"
mRNA 822763..824631
/gene="PGM3"
/locus_tag="YMR278W"
/product="phosphoglucomutase PGM3"
/transcript_id="NM_001182785.1"
/db_xref="GI:296147399"
/db_xref="GeneID:855321"
CDS 822763..824631
/gene="PGM3"
/locus_tag="YMR278W"
/note="Phosphoglucomutase, catalyzes interconversion of
glucose-1-phosphate and glucose-6-phospate; transcription
induced in response to stress; green fluorescent protein
(GFP)-fusion protein localizes to the cytoplasm and
nucleus; non-essential"
/codon_start=1
/product="phosphoglucomutase PGM3"
/protein_id="NP_014005.1"
/db_xref="GI:6323934"
/db_xref="SGD:S000004891"
/db_xref="GeneID:855321"
/translation="MLQGILETVPSDLKDPISLWFKQDRNPKTIEEVTALCKKSDWNE
LHKRFDSRIQFGTAGLRSQMQAGFSRMNTLVVIQASQGLATYVRQQFPDNLVAVVGHD
HRFHSKEFARATAAAFLLKGFKVHYLNPDHEFVHTPLVPFAVDKLKASVGVMITASHN
PKMDNGYKVYYSNGCQIIPPHDHAISDSIDANLEPWANVWDFDDVLNKALKQGKLMYS
REEMLKLYLEEVSKNLVEINPLKLEVKAKPWFVYTPMHGVGFDIFSTIVKKTLCLVEG
KDYLCVPEQQNPDPSFPTVGFPNPEEKGALDIGINLAEKHDIDLLVANDPDADRFSVA
VKDMQSGEWRQLTGNEIGFLFAFYEYQKYKSMDKEFQHVHPLAMLNSTVSSQMIKKMA
EIEGFHYEDTLTGFKWIGNRAILLEKKGYYVPFGFEEAIGYMFPAMEHDKDGISASIV
FLQAYCKWKIDHNLDPLNVLENGFKKYGVFKEYNGYYVVPNPTVTKDIFDYIRNVYTP
EGASYPSSIGEEIEVLYYRDLTTGYQSDTINHKPTLPVDPTSQMITVSARPSNGSENE
HIRFTIRGSGTEPKLKVYIEACANEEQRASFLAKLTWNVLRREWFRPDEMNIVTKF"
gene complement(824729..826351)
/locus_tag="YMR279C"
/db_xref="GeneID:855322"
mRNA complement(824729..826351)
/locus_tag="YMR279C"
/product="hypothetical protein"
/transcript_id="NM_001182786.1"
/db_xref="GI:296147400"
/db_xref="GeneID:855322"
CDS complement(824729..826351)
/locus_tag="YMR279C"
/note="Putative boron transporter involved in boron efflux
and resistance; overexpression mutant but not null mutant
displays boron tolerance phenotype; identified as a
heat-induced gene in a high-throughout screen; YMR279C is
not an essential gene; YMR279C has a paralog, ATR1, that
arose from the whole genome duplication"
/codon_start=1
/product="hypothetical protein"
/protein_id="NP_014006.1"
/db_xref="GI:6323935"
/db_xref="SGD:S000004892"
/db_xref="GeneID:855322"
/translation="MFSIFKKKTSVQGTDSEIDEKITVKAKDKVVVSTEDEEVTTIVS
STKSTQVTNDSPWQDPTYFSSFGKELMFIATCMLAQLLNQAGQTHALCIMNVLSKSFN
SEANNQAWLMASFPLAAGSFILISGRLGDIYGLKKMLIVGYVIVIVWSIISGLSKYSN
SDAFFITSRAFQGVGIAFILPNIMGLVGHVYKVGSFRKNIVISFIGACAPTGGMFGGL
FGGLIVTEDPNQWPWVFYAFGIATFLSLLMAWYSIPNNVPTNIHGLSMDWTGSALAII
GLILFNFVWNQAPIVGWDKPYIIVLLIISVIFLVAFFVYESKYAEVPLLPRAMTKNRH
MIMILLAVFLGWGSFGIWTFYYVSFQLNLRHYSPVWTGGTYFVFVIFGSMAAFFVAFS
IKRLGPALLLCFSLMAFDAGSIMFSVLPVEQSYWKLNFAMQAILCFGMDLSFPASSII
LSDGLPMQYQGMAGSLVNTVINYSASLCLGMGGTVEHQINKSGNDLLKGYRAAVYLGV
GLASLGVVISVTYMLENLWNRHRKSEDRSLEA"
gene complement(827028..831329)
/gene="CAT8"
/locus_tag="YMR280C"
/gene_synonym="DIL1; MSP8"
/db_xref="GeneID:855323"
mRNA complement(827028..831329)
/gene="CAT8"
/locus_tag="YMR280C"
/gene_synonym="DIL1; MSP8"
/product="Cat8p"
/transcript_id="NM_001182787.1"
/db_xref="GI:296147401"
/db_xref="GeneID:855323"
CDS complement(827028..831329)
/gene="CAT8"
/locus_tag="YMR280C"
/gene_synonym="DIL1; MSP8"
/note="Zinc cluster transcriptional activator; necessary
for derepression of a variety of genes under
non-fermentative growth conditions, active after diauxic
shift, binds carbon source responsive elements; relative
distribution to the nucleus increases upon DNA replication
stress"
/codon_start=1
/product="Cat8p"
/protein_id="NP_014007.1"
/db_xref="GI:6323936"
/db_xref="SGD:S000004893"
/db_xref="GeneID:855323"
/translation="MANNNSDRQGLEPRVIRTLGSQALSGPSISNRTSSSEANPHFSK
NVKEAMIKTASPTPLSTPIYRIAQACDRCRSKKTRCDGKRPQCSQCAAVGFECRISDK
LLRKAYPKGYTESLEERVRELEAENKRLLALCDIKEQQISLVSQSRPQTSTDNTINGN
FKHDLKDAPLNLSSTNIYLLNQTVNKQLQNGKMDGDNSGSAMSPLGAPPPPPHKDHLC
DGVSCTNHLHVKPTSTSLNDPTAISFEQDEAPGLPAVKALKSMTTHQRSTQLATLVSL
SIPRSTEEILFIPQLLTRIRQIFGFNSKQCLYTVSLLSSLKNRLPAPRLLAPSTSTKL
KEKDEDKKLDDDSAFVKRFQSTNLSEFVDLKKFLISLKFNINSFSKQSEKPANDQDDE
LLSLTEIKELLHLFFKFWSNQVPILNNDHFLIYFNNFVEVVKHLSTENLETNNTTKST
VTTNHEIFALKLLMMLQMGLLVKIKMEKIKYTVPKNPKAKYARLMAYYHQLSLIIPKN
PYFLNMSTTSLPSLQLLSLASFYYLNVGDISAIYGVRGRIVSMAQQLRLHRCPSAVLS
VHSNPVLQKFEQSERRLLFWAIYYVDVFASLQLGVPRLLKDFDIECALPISDVEYKDQ
LSMENEKADKKAKKIQLQGQVSSFSLQIIRFAKILGNILDSIFKRGMMDERITSEVAL
VHENALDNWRNQLPEMYYFQITVNGTVNLDEIRATNQRNTETKFDKKDIILFEKKILL
LFYFLAKSMIHLPVIATKPLPKNVDNATKKKQSMFNNDSKGATNQDHMILDVDMTSPA
IRTSSSYIILQQATNATLTIFQAINSMYLPLPLNVSRTLIRFSLLCARGSLEYTKGGA
LFLDNKNLLLDTIKDIENDRLLDLPGIASWHTLKLFDMSINLLLKAPNVKVERLDKFL
EKKLNYYNRLMGLPPATTTSLKPLFGSQSKNSLENRQRTPNVKRENPEHEYLYGNDSN
NNNNSEAGHSPMTNTTNGNKRLKYEKDAKRNAKDGGISKGENAHNFQNDTKKNMSTSN
LFPFSFSNTDLTALFTHPEGPNCTNTNNGNVDVCNRASTDATDANIENLSFLNMAPFL
QTGNSNIGQNTIENKPMHMDAIFSLPSNLDLMKDNMDSKPEQLEPVIKQNPENSKNNQ
FHQKGKSTNMEKNNLSFNNKSNYSLTKLMRLLNNDNSFSNISINNFLYQNDQNSASAD
PGTNKKAVTNAGANFKPPSTGSNTSQGSILGSTKHGMDNCDFNDLGNFNNFMTNVNYS
GVDYDYIVDASLGLAPLLVDTPDISNTNTTSTTSNRSKNSIILDTTFNDDLDRSRMNA
REVLNPTDSILSQGMVSSVSTRNTSNQRSLSSGNDSKGDSSSQENSKSATGNQLDTPS
TLFQMRRTSSGPSASHRGPRRPQKNRYNTDRSKSSGGGSSNTDNVSDLFQWQNAK"
gene 832339..833253
/gene="GPI12"
/locus_tag="YMR281W"
/db_xref="GeneID:855324"
mRNA 832339..833253
/gene="GPI12"
/locus_tag="YMR281W"
/product="Gpi12p"
/transcript_id="NM_001182788.1"
/db_xref="GI:296147402"
/db_xref="GeneID:855324"
CDS 832339..833253
/gene="GPI12"
/locus_tag="YMR281W"
/EC_number="3.5.1.89"
/note="ER membrane protein involved in the second step of
glycosylphosphatidylinositol (GPI) anchor assembly, the
de-N-acetylation of the
N-acetylglucosaminylphosphatidylinositol intermediate;
functional homolog of human PIG-Lp"
/codon_start=1
/product="Gpi12p"
/protein_id="NP_014008.1"
/db_xref="GI:6323937"
/db_xref="SGD:S000004894"
/db_xref="GeneID:855324"
/translation="MKMLRRTKVNFSKLLYKITKLAIVLTILYIYFTPKIVSRNNASL
QHIFPHKYGDYEINLVIAHPDDEVMFFSPIISQLNSYFPRTVPFNIICLSKGNAEGLG
ETRVRELNESAALLLHNERAVSVQVMDFQDGMDEIWDIDSITSSLSQKIDIKNHNLNQ
IIVTFDSYGVSNHINHKSCYAAVKKLVDDYAQPKTKRNEQPPHVTALYLRSYKNNIVL
KYNSFIWEILKILYDLISPFRRIIQALPPNTAAEKDKLSLMNTHAQYVLAFATMLNAH
ESQVVWFRYGWWIFSRFVFVNEFDVYTY"
STS 832718..832927
/gene="GPI12"
/locus_tag="YMR281W"
/standard_name="px-64e4"
/db_xref="UniSTS:258445"
gene complement(833356..835098)
/gene="AEP2"
/locus_tag="YMR282C"
/gene_synonym="ATP13"
/db_xref="GeneID:855325"
mRNA complement(833356..835098)
/gene="AEP2"
/locus_tag="YMR282C"
/gene_synonym="ATP13"
/product="Aep2p"
/transcript_id="NM_001182789.1"
/db_xref="GI:296147403"
/db_xref="GeneID:855325"
CDS complement(833356..835098)
/gene="AEP2"
/locus_tag="YMR282C"
/gene_synonym="ATP13"
/note="Mitochondrial protein, likely involved in
translation of the mitochondrial OLI1 mRNA; exhibits
genetic interaction with the OLI1 mRNA 5'-untranslated
leader"
/codon_start=1
/product="Aep2p"
/protein_id="NP_014009.1"
/db_xref="GI:6323938"
/db_xref="SGD:S000004895"
/db_xref="GeneID:855325"
/translation="MWINRLVKHPSYSVLRFYTKRLCTVSVKSLREFGVLPNSTICHS
VYPRRTYVMGRAVINDILIKKSYSTHTVCAIDRSKDENNGSAYDKFEAKGIPIDVHTL
KRIISSSGMDESEFSKSISYLFAKTVDPEPKDVLSLEDLSFLLSKLYTQRFQIRRICR
DINAKYSEFWFKLFSLYAEKVDAKRNQVNLRNTKLDACEIFDANLMIKNFIELGQLGK
AQKILSFILDRNPDILLSPKNADISTIVHFLQLRCGALAPYWKIPDNSEQKQGFLRKM
VRLGAKNTSIRLSSTYKAMDHQTLLKIADLALQEKKLLNSEDLLSTLIQSFGHLGQTQ
ILERCIEHIWQISPQEFPSHVVIKHRGCYPSSKILVSILVSFYFNDHDLHRGLSILDS
FIKHYPDVKLDALFWRRLFQLSHFAWTPANDKKATSVVRCWHLMKQWYASKRLRPSVD
YETLRQLYDIMKKTGNFPLGIDVLRSFKPGIERTRAENAGKVNNIIIKYQKCIIKELV
NRGRFSAVREFIDSYGFDRKMTKDLNIFCANRMFLRSKKMKNKIENKKEREKVRLDSF
DDDEDDGMIIGSLW"
gene complement(835326..836867)
/gene="RIT1"
/locus_tag="YMR283C"
/db_xref="GeneID:855326"
mRNA complement(835326..836867)
/gene="RIT1"
/locus_tag="YMR283C"
/product="Rit1p"
/transcript_id="NM_001182790.1"
/db_xref="GI:296147404"
/db_xref="GeneID:855326"
CDS complement(835326..836867)
/gene="RIT1"
/locus_tag="YMR283C"
/EC_number="2.4.2.-"
/note="2'-O-ribosyl phosphate transferase, modifies the
initiator methionine tRNA at position 64 to distinguish it
from elongator methionine tRNA"
/codon_start=1
/product="Rit1p"
/protein_id="NP_014010.1"
/db_xref="GI:6323939"
/db_xref="SGD:S000004896"
/db_xref="GeneID:855326"
/translation="MVSRLSKRYRSRVQFSISVMDENIYLSLSQINKDIRKENKSVRN
RLQSILLDNKFLQDRVIPIFPHYPLIPNERCGLWYCNPSSFKQTSYFKSTDGHVNQWD
FSTRRLNFHLLETIRDNKGIIIVDSTRRGKKIPDALSKTVPIWCAVLNTLMLQETEKN
VAIDKVLYLPPETVPKSEYDMIKRKIPELVAKLQKLNIIDSKKLNELFMGKLLRPIWV
HPGSSLLDHSVDYFTGEVQEYEAWETPEDQNIIPIILCTVSYQAQDGMDKRYGFTYVQ
GAADDHELWSFGLDSNMFWAHIEYLGDASYSDDQLHDYIMDLAAAKLRNQCYIQDKGS
LDEVFGNIDKITNEISLGKVSSGLTINKNLKQKLKSEYGKVIIFSNSVTVAEDTDDEE
ESGTDPFISIYKLQSGDKKSSKALRSTFPRIHGEIQSLFTNRDEKIKPMLICCNTGTD
MSIGVILSILCTKYTEEWMLTSELPDISKLIVRKHLTKLISHLKGRNVNPSRATLNSV
NSFLM"
LTR 837450..837764
/note="Ty1 LTR"
/db_xref="SGD:S000007127"
rep_origin 837764..837928
/note="ARS1331;
Putative replication origin, identified in multiple array
studies, not yet confirmed by plasmid-based assay"
/db_xref="SGD:S000130192"
gene 837928..838016
/gene="SUP8"
/locus_tag="tY(GUA)M2"
/db_xref="GeneID:855327"
tRNA join(837928..837966,837981..838016)
/gene="SUP8"
/locus_tag="tY(GUA)M2"
/product="tRNA-Tyr"
/note="Tyrosine tRNA (tRNA-Tyr), predicted by tRNAscan-SE
analysis; can mutate to suppress ochre nonsense mutations"
/db_xref="SGD:S000006784"
/db_xref="GeneID:855327"
gene 838187..839995
/gene="YKU70"
/locus_tag="YMR284W"
/gene_synonym="HDF1; NES24"
/db_xref="GeneID:855328"
mRNA 838187..839995
/gene="YKU70"
/locus_tag="YMR284W"
/gene_synonym="HDF1; NES24"
/product="Yku70p"
/transcript_id="NM_001182791.1"
/db_xref="GI:296147405"
/db_xref="GeneID:855328"
CDS 838187..839995
/gene="YKU70"
/locus_tag="YMR284W"
/gene_synonym="HDF1; NES24"
/note="Subunit of the telomeric Ku complex
(Yku70p-Yku80p), involved in telomere length maintenance,
structure and telomere position effect; relocates to sites
of double-strand cleavage to promote nonhomologous end
joining during DSB repair"
/codon_start=1
/product="Yku70p"
/protein_id="NP_014011.1"
/db_xref="GI:6323940"
/db_xref="SGD:S000004897"
/db_xref="GeneID:855328"
/translation="MRSVTNAFGNSGELNDQVDETGYRKFDIHEGILFCIELSETMFK
ESSDLEYKSPLLEILESLDELMSQLVITRPGTAIGCYFYYCNREDAKEGIYELFPLRD
INATFMKKLNDLLEDLSSGRISLYDYFMFQQTGSEKQVRLSVLFTFMLDTFLEEIPGQ
KQLSNKRVFLFTDIDKPQEAQDIDERARLRRLTIDLFDNKVNFATFFIGYADKPFDNE
FYSDILQLGSHTNENTGLDSEFDGPSTKPIDAKYIKSRILRKKEVKRIMFQCPLILDE
KTNFIVGVKGYTMYTHEKAGVRYKLVYEHEDIRQEAYSKRKFLNPITGEDVTGKTVKV
YPYGDLDINLSDSQDQIVMEAYTQKDAFLKIIGFRSSSKSIHYFNNIDKSSFIVPDEA
KYEGSIRTLASLLKILRKKDKIAILWGKLKSNSHPSLYTLSPSSVKDYNEGFYLYRVP
FLDEIRKFPSLLSYDDGSEHKLDYDNMKKVTQSIMGYFNLRDGYNPSDFKNPLLQKHY
KVLHDYLLQIETTFDENETPNTKKDRMMREDDSLRKLYYIRNKILESEKSEDPIIQRL
NKYVKIWNMFYKKFNDDNISIKEEKKPFDKKPKFNI"
gene complement(840144..841691)
/gene="NGL2"
/locus_tag="YMR285C"
/db_xref="GeneID:855329"
mRNA complement(840144..841691)
/gene="NGL2"
/locus_tag="YMR285C"
/product="Ngl2p"
/transcript_id="NM_001182792.1"
/db_xref="GI:296147406"
/db_xref="GeneID:855329"
CDS complement(840144..841691)
/gene="NGL2"
/locus_tag="YMR285C"
/EC_number="3.1.-.-"
/note="Protein involved in 5.8S rRNA processing;
Ccr4p-like RNase required for correct 3'-end formation of
5.8S rRNA at site E; similar to Ngl1p and Ngl3p"
/codon_start=1
/product="Ngl2p"
/protein_id="NP_014012.1"
/db_xref="GI:6323941"
/db_xref="SGD:S000004898"
/db_xref="GeneID:855329"
/translation="MTQDKEVKVVAPDVAPDQEVEINKSVKDAKHQTNDDSLLQHKKK
GKKGKKSKPIVTPEHIAKVRAEREVMRKAKRDAMLAQGVDPDCPPELHFIRRPFLSLH
EAEPVTGFRFKLMTYNCLAQALIRRKLFPDSGDALKWYRRSKVLLNEFKYYNSDVICL
QEIDHIQFQSFWKDEFSKLGYDGQYYRNATKNHGVAIMWRRELFHQVDKMLIDYDKES
SESISTRTTTNNVGLVLALKFSEKVLSNLGKKSSKKCGILIGTTHLFWHPFGTYERTR
QCYIVLKKMKEFMHRVNVLQNENDGDLSHWFPFFCGDFNSQPFDTPYLSMTSKPVHYR
NRAKTVIGCSTSYKFSKVRDGEEGADDEEGGNIEKYGKDQPESPVPEKFHANEEQSEL
VDKMAQLHNSLDMRAISLYSVGYKNVHPENAGLDNDRGEPEISNWANTWRGLLDYLFY
VKKWDPQSNCQEVETLGDFEKENKVKCRGFLRMPPGNEMTKHGQPHVGEYASDHLSMV
CDLELQL"
gene 841942..842202
/gene="MRPL33"
/locus_tag="YMR286W"
/db_xref="GeneID:855330"
mRNA 841942..842202
/gene="MRPL33"
/locus_tag="YMR286W"
/product="mitochondrial 54S ribosomal protein YmL33"
/transcript_id="NM_001182793.1"
/db_xref="GI:296147407"
/db_xref="GeneID:855330"
CDS 841942..842202
/gene="MRPL33"
/locus_tag="YMR286W"
/note="Mitochondrial ribosomal protein of the large
subunit"
/codon_start=1
/product="mitochondrial 54S ribosomal protein YmL33"
/protein_id="NP_014013.1"
/db_xref="GI:6323942"
/db_xref="SGD:S000004899"
/db_xref="GeneID:855330"
/translation="MVFYKVTLSRSLIGVPHTTKSIVKSLGLGKRGSIVYKKVNPAIA
GSLAKVKELVKVEVTEHELTPSQQRELRKSNPGFIVEKRTID"
gene complement(842436..845345)
/gene="DSS1"
/locus_tag="YMR287C"
/gene_synonym="MSU1"
/db_xref="GeneID:855331"
mRNA complement(842436..845345)
/gene="DSS1"
/locus_tag="YMR287C"
/gene_synonym="MSU1"
/product="Dss1p"
/transcript_id="NM_001182794.1"
/db_xref="GI:296147408"
/db_xref="GeneID:855331"
CDS complement(842436..845345)
/gene="DSS1"
/locus_tag="YMR287C"
/gene_synonym="MSU1"
/EC_number="3.1.13.1"
/note="3'-5' exoribonuclease, component of the
mitochondrial degradosome along with the ATP-dependent RNA
helicase Suv3p; the degradosome associates with the
ribosome and mediates turnover of aberrant or unprocessed
RNAs"
/codon_start=1
/product="Dss1p"
/protein_id="NP_014014.1"
/db_xref="GI:6323943"
/db_xref="SGD:S000004900"
/db_xref="GeneID:855331"
/translation="MVVRRKVHVLLIARSFHSYTPCFRVTTRGKRQRSKSKQQAKVEL
DHTRELDNDQATETVVDRSVGPEKDIESINKDFLQRTKGLEPDIELKQLPQIKQEFNQ
RYKDRYVKPSEDWYVNSWRSLTKPKIPLYKLINSDFQLITKLKAPNPMEFQPVQLMES
PLNVGDFVLLKMRPNELAMCVSLPSSTMDPRYTFVTIDGTMCFATKNRVLLRIPHKLP
AGIHSLIQPESHHKHLPIGTVKNFSNQTNILPIVARQLITSRYPAQISKLAWKDLPIT
TKKLQLLHRSLQNYMGPWQIPFFTLVGLVQKLDLNKALDDKNGINYLTSLVNNYHTVN
DIPINSPTFVSTYWAIMQQQESNLWGEIHLNTALLSPISVTIIPLKSQHLYYAQVIEK
LEANSYREVNKFVKLVNERKYRDISALYPSVIQLLKDFAAGNFHNNGIIVALISKIFR
KIERYKDCDITRDICQDLINEITPNSIPNPLLLNMDLALPASSKLVKWQQKLYDLTNI
EELQWKKSGTDDDRYDFGDLRVFCIDSETAHEIDDGVSVKNYGRDGLYTLYIHIADPT
SMFPESTNVDIEGISTDILNVALKRSFTTYLPDTVVPMLPQSICHLSDLGKQGQRTKT
ISFSVDVKITSKCSGKSIEIMYDSFKIRKGIVSNFPKATYEDVDRILGTPNSEASPVK
KDLESLSMISKLLREQRIKNSNAVIFGEGFNKGLVMLNADSEGELTEVTFSDQEETLS
TILVSEMMILANTLTGRYFAENKIGGVFRCYKQLPLGEVAQQQYDSMITSTKKGIFPK
LKDIVKLSSLLNSSFYTGRPFRHEMIGAKQYLTVTSPLRRFPDLINHLQIHRHLQKKP
LCFNQTQIDSLIWPIQSRADILKRASRNSSTYWTLNYLKKLTKLEPERTFDVMVTSVP
QNGFTGCVFPDLSFARGTLKLHPSSMHYPMIGDIVKNCKISKIDCLEGMLELEKL"
gene 845571..848486
/gene="HSH155"
/locus_tag="YMR288W"
/db_xref="GeneID:855332"
mRNA 845571..848486
/gene="HSH155"
/locus_tag="YMR288W"
/product="Hsh155p"
/transcript_id="NM_001182795.1"
/db_xref="GI:296147409"
/db_xref="GeneID:855332"
CDS 845571..848486
/gene="HSH155"
/locus_tag="YMR288W"
/note="U2-snRNP associated splicing factor that forms
extensive associations with the branch site-3' splice
site-3' exon region upon prespliceosome formation;
similarity to the mammalian U2 snRNP-associated splicing
factor SAP155"
/codon_start=1
/product="Hsh155p"
/protein_id="NP_014015.1"
/db_xref="GI:6323944"
/db_xref="SGD:S000004901"
/db_xref="GeneID:855332"
/translation="MSHPIQFVNANNSDKSHQLGGQYSIPQDLRENLQKEAARIGENE
KDVLQEKMETRTVQNREDSYHKRRFDMKFEPDSDTQTVTSSENTQDAVVPRKRKSRWD
VKGYEPPDESSTAVKENSDSALVNVEGIHDLMFFKPSDHKYFADVISKKPIDELNKDE
KKERTLSMLLLKIKNGNTASRRTSMRILTDKAVTFGPEMIFNRLLPILLDRSLEDQER
HLMIKTIDRVLYQLGDLTKPYVHKILVVAAPLLIDEDPMVRSTGQEIITNLSTVAGLK
TILTVMRPDIENEDEYVRNVTSRAAAVVAKALGVNQLLPFINAACHSRKSWKARHTGI
KIVQQIGILLGIGVLNHLTGLMSCIKDCLMDDHVPVRIVTAHTLSTLAENSYPYGIEV
FNVVLEPLWKGIRSHRGKVLSSFLKAVGSMIPLMDPEYAGYYTTEAMRIIRREFDSPD
DEMKKTILLVLQKCSAVESITPKFLREEIAPEFFQKFWVRRVALDRPLNKVVTYTTVT
LAKKLGCSYTIDKLLTPLRDEAEPFRTMAVHAVTRTVNLLGTADLDERLETRLIDALL
IAFQEQTNSDSIIFKGFGAVTVSLDIRMKPFLAPIVSTILNHLKHKTPLVRQHAADLC
AILIPVIKNCHEFEMLNKLNIILYESLGEVYPEVLGSIINAMYCITSVMDLDKLQPPI
NQILPTLTPILRNKHRKVEVNTIKFVGLIGKLAPTYAPPKEWMRICFELLELLKSTNK
EIRRSANATFGFIAEAIGPHDVLVALLNNLKVQERQLRVCTAVAIGIVAKVCGPYNVL
PVIMNEYTTPETNVQNGVLKAMSFMFEYIGNMSKDYIYFITPLLEDALTDRDLVHRQT
ASNVITHLALNCSGTGHEDAFIHLMNLLIPNIFETSPHAIMRILEGLEALSQALGPGL
FMNYIWAGLFHPAKNVRKAFWRVYNNMYVMYQDAMVPFYPVTPDNNEEYIEELDLVL"
gene 848685..849809
/gene="ABZ2"
/locus_tag="YMR289W"
/db_xref="GeneID:855333"
mRNA 848685..849809
/gene="ABZ2"
/locus_tag="YMR289W"
/product="aminodeoxychorismate lyase ABZ2"
/transcript_id="NM_001182796.1"
/db_xref="GI:296147410"
/db_xref="GeneID:855333"
CDS 848685..849809
/gene="ABZ2"
/locus_tag="YMR289W"
/note="Aminodeoxychorismate lyase
(4-amino-4-deoxychorismate lyase), catalyzes the third
step in para-aminobenzoic acid biosynthesis; involved in
folic acid biosynthesis"
/codon_start=1
/product="aminodeoxychorismate lyase ABZ2"
/protein_id="NP_014016.1"
/db_xref="GI:6323945"
/db_xref="SGD:S000004902"
/db_xref="GeneID:855333"
/translation="MSLMDNWKTDMESYDEGGLVANPNFEVLATFRYDPGFARQSASK
KEIFETPDPRLGLRDEDIRQQIINEDYSSYLRVREVNSGGDLLENIQHPDAWKHDCKT
IVCQRVEDMLQVIYERFFLLDEQYQRIRIALSYFKIDFSTSLNDLLKLLVENLINCKE
GNSEYHEKIQKMINERQCYKMRVLVSKTGDIRIEAIPMPMEPILKLTTDYDSVSTYFI
KTMLNGFLIDSTINWDVVVSSEPLNASAFTSFKTTSRDHYARARVRMQTAINNLRGSE
PTSSVSQCEILFSNKSGLLMEGSITNVAVIQKDPNGSKKYVTPRLATGCLCGTMRHYL
LRLGLIEEGDIDIGSLTVGNEVLLFNGVMGCIKGTVKTKY"
gene complement(850074..851591)
/gene="HAS1"
/locus_tag="YMR290C"
/db_xref="GeneID:855335"
mRNA complement(850074..851591)
/gene="HAS1"
/locus_tag="YMR290C"
/product="ATP-dependent RNA helicase HAS1"
/transcript_id="NM_001182797.1"
/db_xref="GI:296147411"
/db_xref="GeneID:855335"
CDS complement(850074..851591)
/gene="HAS1"
/locus_tag="YMR290C"
/EC_number="3.6.1.-"
/note="ATP-dependent RNA helicase; localizes to both the
nuclear periphery and nucleolus; highly enriched in
nuclear pore complex fractions; constituent of 66S
pre-ribosomal particles"
/codon_start=1
/product="ATP-dependent RNA helicase HAS1"
/protein_id="NP_014017.1"
/db_xref="GI:6323947"
/db_xref="SGD:S000004903"
/db_xref="GeneID:855335"
/translation="MATPSNKRSRDSESTEEPVVDEKSTSKQNNAAPEGEQTTCVEKF
EELKLSQPTLKAIEKMGFTTMTSVQARTIPPLLAGRDVLGAAKTGSGKTLAFLIPAIE
LLHSLKFKPRNGTGIIVITPTRELALQIFGVARELMEFHSQTFGIVIGGANRRQEAEK
LMKGVNMLIATPGRLLDHLQNTKGFVFKNLKALIIDEADRILEIGFEDEMRQIIKILP
NEDRQSMLFSATQTTKVEDLARISLRPGPLFINVVPETDNSTADGLEQGYVVCDSDKR
FLLLFSFLKRNQKKKIIVFLSSCNSVKYYAELLNYIDLPVLELHGKQKQQKRTNTFFE
FCNAERGILICTDVAARGLDIPAVDWIIQFDPPDDPRDYIHRVGRTARGTKGKGKSLM
FLTPNELGFLRYLKASKVPLNEYEFPENKIANVQSQLEKLIKSNYYLHQTAKDGYRSY
LQAYASHSLKTVYQIDKLDLAKVAKSYGFPVPPKVNITIGASGKTPNTKRRKTHK"
gene 852630..854390
/gene="TDA1"
/locus_tag="YMR291W"
/db_xref="GeneID:855336"
mRNA 852630..854390
/gene="TDA1"
/locus_tag="YMR291W"
/product="Tda1p"
/transcript_id="NM_001182799.1"
/db_xref="GI:296147412"
/db_xref="GeneID:855336"
CDS 852630..854390
/gene="TDA1"
/locus_tag="YMR291W"
/EC_number="2.7.11.1"
/note="Protein kinase of unknown cellular role; green
fluorescent protein (GFP)-fusion protein localizes to the
cytoplasm and nucleus; null mutant is sensitive to
expression of the top1-T722A allele; not an essential
gene; relocalizes from nucleus to cytoplasm upon DNA
replication stress"
/codon_start=1
/product="Tda1p"
/protein_id="NP_014019.1"
/db_xref="GI:6323948"
/db_xref="SGD:S000004905"
/db_xref="GeneID:855336"
/translation="MTTASSSASQLQQRLPEEKPWPQLSGSNADAQTFKCKYVTNHNS
LGDGNFSVVKECMNIHTKDLYAMKLIKKQTVKNKIQLIQREFDLLRSISEKIRDMEKK
NEHSLDIFEGHHHILQLFDYFETADNIVLITQLCQKGDLYEKIVENQCLDLETQVTSY
CACLVSVLEFLHSQGIVHRDLKAENVLFRLRVNENEKNLQGEHHGDFKYDLLAHDLVL
ADFGLAAEYNTSKVNSLKEFVGTISYIAPEIVKCKGVGEMTPDQVGKLDKYGCPVDIW
ALGVLTYFMAFGYTPFDCTTDDETLECISKCDYYVDEQMMHDPKYEQFWNFVQCCFTI
DPAVRRSAKNLKQHPFIKDYFATSNSLNTKDTPNFSFHPTIRRVSSTASMHTLRSPSK
SRKTTTLAYLNMDGGSSETSTAFSSKMDLPDLYVDRTINSRERSLNRIRDTLKKTLSM
TSLKPAGTFDYLHANKNGTSLSSSKSGLVKKNSTFVLDPKPPKNSLMNGCFSTTPESR
SNFNTPKTLSRQGSSTSVKKYVNEVDLLLTPRTASMSSNDTTAINDYDTTNDKNPARK
HAASFQVNVDDSDGDETMQI"
gene 854795..855293
/gene="GOT1"
/locus_tag="YMR292W"
/db_xref="GeneID:855337"
mRNA join(854795..854816,854899..855293)
/gene="GOT1"
/locus_tag="YMR292W"
/product="Got1p"
/transcript_id="NM_001182800.1"
/db_xref="GI:296147413"
/db_xref="GeneID:855337"
CDS join(854795..854816,854899..855293)
/gene="GOT1"
/locus_tag="YMR292W"
/note="Homodimeric protein that is packaged into COPII
vesicles and cycles between the ER and Golgi; involved in
secretory transport but not directly required for aspects
of transport assayed in vitro; may influence membrane
composition"
/codon_start=1
/product="Got1p"
/protein_id="NP_014020.1"
/db_xref="GI:6323949"
/db_xref="SGD:S000004906"
/db_xref="GeneID:855337"
/translation="MWLTEAQKFGVAFTFGGFLFFLFGIFTFFDRALLALGNILFLIG
VFLIIGSQKTYIFFTRPNKRRGSLFFLVGAFLILLKWTFLGFIIESLGIIGLFGDFFG
VIVQFLRSMPIIGPILSHPAIAPIVDKLAGVRVLPV"
gene complement(855399..856793)
/gene="HER2"
/locus_tag="YMR293C"
/gene_synonym="GEP6; RRG6"
/db_xref="GeneID:855338"
mRNA complement(855399..856793)
/gene="HER2"
/locus_tag="YMR293C"
/gene_synonym="GEP6; RRG6"
/product="glutamyl-tRNA(Gln) amidotransferase subunit
HER2"
/transcript_id="NM_001182801.1"
/db_xref="GI:296147414"
/db_xref="GeneID:855338"
CDS complement(855399..856793)
/gene="HER2"
/locus_tag="YMR293C"
/gene_synonym="GEP6; RRG6"
/EC_number="3.5.1.4"
/note="Subunit of the trimeric GatFAB
AmidoTransferase(AdT) complex; involved in the formation
of Q-tRNAQ; required for remodeling of ER caused by Hmg2p
overexpression; similar to bacterial GatA glutamyl-tRNA
amidotransferase"
/codon_start=1
/product="glutamyl-tRNA(Gln) amidotransferase subunit
HER2"
/protein_id="NP_014021.1"
/db_xref="GI:6323950"
/db_xref="SGD:S000004907"
/db_xref="GeneID:855338"
/translation="MPLKRSLKESIERLSSFQSKYNIFTSINPSPYSITNKKGTKETL
TGCVASIKDNIVTKDFPTTCASHILENFKSPFDATVVKLLKQAGVHILGKTNLDEFGM
GSGGVHSIRGPVINPLYPHEDKKIMGGSSSGAAASVACDLVDFALGTDTGGSVRLPAC
YGSVLGFKPSYGRLSRFGVIAYSQSLDTVGILSKKINVLRKVFHTLDKYDMKDPTSLS
VELRELIEGNKKVRRPLKVGIVKEFSHESMPIGFHRLYLSLLEKLINLGLEIYPVSIP
SVKNCLPIYYTLSPAEAASNLSRYDGIRYGYRDSELDIKDGILFAPTRSKFGTEVKNR
IILGNYNLCSDAFKNNFIKAEKLRVNLIDEFDGIFRFPNVLTNSKGNPDGLDLLIVPT
SSKLPGSIRDFEEEEAKSPANSYINDVFTVPMSLAGLPSLSMPLKEKTPIGLQVVGQY
GDDSTVLDFVESIS"
gene 856966..858087
/gene="JNM1"
/locus_tag="YMR294W"
/gene_synonym="INS1; PAC3"
/db_xref="GeneID:855339"
mRNA 856966..858087
/gene="JNM1"
/locus_tag="YMR294W"
/gene_synonym="INS1; PAC3"
/product="Jnm1p"
/transcript_id="NM_001182802.1"
/db_xref="GI:296147415"
/db_xref="GeneID:855339"
CDS 856966..858087
/gene="JNM1"
/locus_tag="YMR294W"
/gene_synonym="INS1; PAC3"
/note="Component of the yeast dynactin complex, consisting
of Nip100p, Jnm1p, and Arp1p; required for proper nuclear
migration and spindle partitioning during mitotic anaphase
B"
/codon_start=1
/product="Jnm1p"
/protein_id="NP_014022.1"
/db_xref="GI:6323951"
/db_xref="SGD:S000004908"
/db_xref="GeneID:855339"
/translation="MNVIDLSDPAINVDYDSLIGIDNEESQEIFENEVKEDGQQEEQE
EASSRKDGLIVEPGRDVESLRRAIRDQLLFKIHRQNQSDCADARKLSNDEEDESRQQK
LERIREELEELKIENLTSEMQTEIKELCEIQSKLATESSSRLTNLRKKLLETYEGQDT
VILPNIILDTSNIKRLQKLDQKISLMERFVGIPEALEAEEDRKSVHSKVNELYRSIQL
LQGDDKAEGKLQKFRDRLVELNEEFENSLLGKKIQQDLRLKDDTVSKLVMPENKVKEI
NSMYSMFKQYQDSLPLLAERMKSLNKMNNRVIEVYETTKGLDSQITSIQEQGKVWLKA
LNELDKKFDEQEVKIRENMEQIRRKIDTLEDEALQRNSK"
gene complement(858297..858890)
/locus_tag="YMR295C"
/db_xref="GeneID:855341"
mRNA complement(858297..858890)
/locus_tag="YMR295C"
/product="hypothetical protein"
/transcript_id="NM_001182804.1"
/db_xref="GI:296147416"
/db_xref="GeneID:855341"
CDS complement(858297..858890)
/locus_tag="YMR295C"
/note="hypothetical protein that associates with
ribosomes; green fluorescent protein (GFP)-fusion protein
localizes to the cell periphery and bud; YMR295C is not an
essential gene; protein abundance increases in response to
DNA replication stress"
/codon_start=1
/product="hypothetical protein"
/protein_id="NP_014024.1"
/db_xref="GI:6323953"
/db_xref="SGD:S000004910"
/db_xref="GeneID:855341"
/translation="MMHFRKKSSISNTSDHDGANRASDVKISEDDKARLKMRTASVAD
PILDAVQEAQPFEQAADTFHDNMNRQSYFSNEEGHVLCDVFGQPITQADISNPTRARD
ERPLDTIRSFEYAVSGDPVWAQQLETPTYGFRVRPDFPVFGAAVTYDANGMPQQVGGA
SSQMYGEQAVYQPQQHVQTEEKQKKKKKGLFGRMKKK"
gene complement(859215..860891)
/gene="LCB1"
/locus_tag="YMR296C"
/gene_synonym="END8; TSC2"
/db_xref="GeneID:855342"
mRNA complement(859215..860891)
/gene="LCB1"
/locus_tag="YMR296C"
/gene_synonym="END8; TSC2"
/product="serine C-palmitoyltransferase LCB1"
/transcript_id="NM_001182805.1"
/db_xref="GI:296147417"
/db_xref="GeneID:855342"
CDS complement(859215..860891)
/gene="LCB1"
/locus_tag="YMR296C"
/gene_synonym="END8; TSC2"
/EC_number="2.3.1.50"
/note="Component of serine palmitoyltransferase,
responsible along with Lcb2p for the first committed step
in sphingolipid synthesis, which is the condensation of
serine with palmitoyl-CoA to form 3-ketosphinganine"
/codon_start=1
/product="serine C-palmitoyltransferase LCB1"
/protein_id="NP_014025.1"
/db_xref="GI:6323954"
/db_xref="SGD:S000004911"
/db_xref="GeneID:855342"
/translation="MAHIPEVLPKSIPIPAFIVTTSSYLWYYFNLVLTQIPGGQFIVS
YIKKSHHDDPYRTTVEIGLILYGIIYYLSKPQQKKSLQAQKPNLSPQEIDALIEDWEP
EPLVDPSATDEQSWRVAKTPVTMEMPIQNHITITRNNLQEKYTNVFNLASNNFLQLSA
TEPVKEVVKTTIKNYGVGACGPAGFYGNQDVHYTLEYDLAQFFGTQGSVLYGQDFCAA
PSVLPAFTKRGDVIVADDQVSLPVQNALQLSRSTVYYFNHNDMNSLECLLNELTEQEK
LEKLPAIPRKFIVTEGIFHNSGDLAPLPELTKLKNKYKFRLFVDETFSIGVLGATGRG
LSEHFNMDRATAIDITVGSMATALGSTGGFVLGDSVMCLHQRIGSNAYCFSACLPAYT
VTSVSKVLKLMDSNNDAVQTLQKLSKSLHDSFASDDSLRSYVIVTSSPVSAVLHLQLT
PAYRSRKFGYTCEQLFETMSALQKKSQTNKFIEPYEEEEKFLQSIVDHALINYNVLIT
RNTIVLKQETLPIVPSLKICCNAAMSPEELKNACESVKQSILACCQESNK"
gene 861922..863520
/gene="PRC1"
/locus_tag="YMR297W"
/gene_synonym="LBC1"
/db_xref="GeneID:855343"
mRNA 861922..863520
/gene="PRC1"
/locus_tag="YMR297W"
/gene_synonym="LBC1"
/product="carboxypeptidase C PRC1"
/transcript_id="NM_001182806.1"
/db_xref="GI:296147418"
/db_xref="GeneID:855343"
CDS 861922..863520
/gene="PRC1"
/locus_tag="YMR297W"
/gene_synonym="LBC1"
/EC_number="3.4.16.5"
/note="Vacuolar carboxypeptidase Y (proteinase C; CPY),
broad-specificity C-terminal exopeptidase involved in
non-specific protein degradation in the vacuole; member of
the serine carboxypeptidase family"
/codon_start=1
/product="carboxypeptidase C PRC1"
/protein_id="NP_014026.1"
/db_xref="GI:6323955"
/db_xref="SGD:S000004912"
/db_xref="GeneID:855343"
/translation="MKAFTSLLCGLGLSTTLAKAISLQRPLGLDKDVLLQAAEKFGLD
LDLDHLLKELDSNVLDAWAQIEHLYPNQVMSLETSTKPKFPEAIKTKKDWDFVVKNDA
IENYQLRVNKIKDPKILGIDPNVTQYTGYLDVEDEDKHFFFWTFESRNDPAKDPVILW
LNGGPGCSSLTGLFFELGPSSIGPDLKPIGNPYSWNSNATVIFLDQPVNVGFSYSGSS
GVSNTVAAGKDVYNFLELFFDQFPEYVNKGQDFHIAGESYAGHYIPVFASEILSHKDR
NFNLTSVLIGNGLTDPLTQYNYYEPMACGEGGEPSVLPSEECSAMEDSLERCLGLIES
CYDSQSVWSCVPATIYCNNAQLAPYQRTGRNVYDIRKDCEGGNLCYPTLQDIDDYLNQ
DYVKEAVGAEVDHYESCNFDINRNFLFAGDWMKPYHTAVTDLLNQDLPILVYAGDKDF
ICNWLGNKAWTDVLPWKYDEEFASQKVRNWTASITDEVAGEVKSYKHFTYLRVFNGGH
MVPFDVPENALSMVNEWIHGGFSL"
gene 863819..864271
/gene="LIP1"
/locus_tag="YMR298W"
/db_xref="GeneID:855344"
mRNA 863819..864271
/gene="LIP1"
/locus_tag="YMR298W"
/product="sphingosine N-acyltransferase subunit LIP1"
/transcript_id="NM_001182807.1"
/db_xref="GI:296147419"
/db_xref="GeneID:855344"
CDS 863819..864271
/gene="LIP1"
/locus_tag="YMR298W"
/note="Ceramide synthase subunit; single-span ER membrane
protein associated with Lag1p and Lac1p and required for
ceramide synthase activity, null mutant grows extremely
slowly and is defective in ceramide synthesis"
/codon_start=1
/product="sphingosine N-acyltransferase subunit LIP1"
/protein_id="NP_014027.1"
/db_xref="GI:6323956"
/db_xref="SGD:S000004913"
/db_xref="GeneID:855344"
/translation="MSQPTPIITTKSAAKPKPKIFNLFRVCFISLLLIAAVEYFKYGT
RINYEWFHCTPIKEPQSGSVIKLWARGGPSCDKRGEYKTIVKRITRDYEPNDEHLSFC
IIENDNVPPVHYPIHEDKGEPGYVAYVGYDTDSELVQELCADSTIYHM"
gene complement(864412..865350)
/gene="DYN3"
/locus_tag="YMR299C"
/db_xref="GeneID:855345"
mRNA complement(864412..865350)
/gene="DYN3"
/locus_tag="YMR299C"
/product="dynein light intermediate chain"
/transcript_id="NM_001182808.2"
/db_xref="GI:330443684"
/db_xref="GeneID:855345"
CDS complement(864412..865350)
/gene="DYN3"
/locus_tag="YMR299C"
/note="Dynein light intermediate chain (LIC); localizes
with dynein, null mutant is defective in nuclear
migration"
/codon_start=1
/product="dynein light intermediate chain"
/protein_id="NP_014028.2"
/db_xref="GI:330443685"
/db_xref="SGD:S000004914"
/db_xref="GeneID:855345"
/translation="MDNCNAWDKLLSQNESTINSTETATITAIIYSPSSKTLHQFINI
CFPEGSNSILDTTLINYATIGWTNDLKENYSVDVYTLIRNTDDALDLLKPFLQEHSSK
VRWLILLDWTLNDQKLWLNELSYAFNKIKQLNDDNEFSVWCLNSGEILNLQRHTTVWQ
SVHIDFILQTLRSFCYFNDSSLFYICEDHTEEKREEAQRLKYQELLKHFCEDRDMKDH
IEMVKRSEILIPKGCDSIGLIKTVDERFEPTEVKEQHFLARYMDFIPTIDKIREDRKT
TSGIDLDKLYPLEVFKVNIQEELGKMFAKYRENSRI"
gene complement(865559..867091)
/gene="ADE4"
/locus_tag="YMR300C"
/db_xref="GeneID:855346"
mRNA complement(865559..867091)
/gene="ADE4"
/locus_tag="YMR300C"
/product="amidophosphoribosyltransferase"
/transcript_id="NM_001182809.1"
/db_xref="GI:296147421"
/db_xref="GeneID:855346"
CDS complement(865559..867091)
/gene="ADE4"
/locus_tag="YMR300C"
/EC_number="2.4.2.14"
/note="Phosphoribosylpyrophosphate amidotransferase
(PRPPAT; amidophosphoribosyltransferase), catalyzes first
step of the 'de novo' purine nucleotide biosynthetic
pathway"
/codon_start=1
/product="amidophosphoribosyltransferase"
/protein_id="NP_014029.1"
/db_xref="GI:6323958"
/db_xref="SGD:S000004915"
/db_xref="GeneID:855346"
/translation="MCGILGIVLANQTTPVAPELCDGCIFLQHRGQDAAGIATCGSRG
RIYQCKGNGMARDVFTQQRVSGLAGSMGIAHLRYPTAGSSANSEAQPFYVNSPYGINL
AHNGNLVNTASLKRYMDEDVHRHINTDSDSELLLNIFAAELEKHNKYRVNNEDVFHAL
EGVYRLCRGGYACVGLLAGFALFGFRDPNGIRPLLFGERENPDGTKDYMLASESVVFK
AHNFTKYRDLKPGEAVIIPKNCSKGEPEFKQVVPINSYRPDLFEYVYFARPDSVLDGI
SVYHTRLAMGSKLAENILKQLKPEDIDVVIPVPDTARTCALECANVLGKPYREGFVKN
RYVGRTFIMPNQRERVSSVRRKLNPMESEFKGKKVLIVDDSIVRGTTSKEIVNMAKES
GATKVYFASAAPAIRYNHIYGIDLTDTKNLIAYNRTDEEVAEVIGCERVIYQSLEDLI
DCCKTDKITKFEDGVFTGNYVTGVEDGYIQELEEKRESIANNSSDMKAEVDIGLYNCA
DY"
gene complement(867555..869627)
/gene="ATM1"
/locus_tag="YMR301C"
/db_xref="GeneID:855347"
mRNA complement(867555..869627)
/gene="ATM1"
/locus_tag="YMR301C"
/product="ATP-binding cassette Fe/S cluster precursor
transporter ATM1"
/transcript_id="NM_001182810.1"
/db_xref="GI:296147422"
/db_xref="GeneID:855347"
CDS complement(867555..869627)
/gene="ATM1"
/locus_tag="YMR301C"
/note="Mitochondrial inner membrane ATP-binding cassette
(ABC) transporter, exports mitochondrially synthesized
precursors of iron-sulfur (Fe/S) clusters to the cytosol"
/codon_start=1
/product="ATP-binding cassette Fe/S cluster precursor
transporter ATM1"
/protein_id="NP_014030.1"
/db_xref="GI:6323959"
/db_xref="SGD:S000004916"
/db_xref="GeneID:855347"
/translation="MLLLPRCPVIGRIVRSKFRSGLIRNHSPVIFTVSKLSTQRPLLF
NSAVNLWNQAQKDITHKKSVEQFSSAPKVKTQVKKTSKAPTLSELKILKDLFRYIWPK
GNNKVRIRVLIALGLLISAKILNVQVPFFFKQTIDSMNIAWDDPTVALPAAIGLTILC
YGVARFGSVLFGELRNAVFAKVAQNAIRTVSLQTFQHLMKLDLGWHLSRQTGGLTRAM
DRGTKGISQVLTAMVFHIIPISFEISVVCGILTYQFGASFAAITFSTMLLYSIFTIKT
TAWRTHFRRDANKADNKAASVALDSLINFEAVKYFNNEKYLADKYNGSLMNYRDSQIK
VSQSLAFLNSGQNLIFTTALTAMMYMGCTGVIGGNLTVGDLVLINQLVFQLSVPLNFL
GSVYRDLKQSLIDMETLFKLRKNEVKIKNAERPLMLPENVPYDITFENVTFGYHPDRK
ILKNASFTIPAGWKTAIVGSSGSGKSTILKLVFRFYDPESGRILINGRDIKEYDIDAL
RKVIGVVPQDTPLFNDTIWENVKFGRIDATDEEVITVVEKAQLAPLIKKLPQGFDTIV
GERGLMISGGEKQRLAIARVLLKNARIMFFDEATSALDTHTEQALLRTIRDNFTSGSR
TSVYIAHRLRTIADADKIIVLDNGRVREEGKHLELLAMPGSLYRELWTIQEDLDHLEN
ELKDQQEL"
gene complement(870073..872625)
/gene="YME2"
/locus_tag="YMR302C"
/gene_synonym="PRP12; RNA12"
/db_xref="GeneID:855348"
mRNA complement(870073..872625)
/gene="YME2"
/locus_tag="YMR302C"
/gene_synonym="PRP12; RNA12"
/product="Yme2p"
/transcript_id="NM_001182811.1"
/db_xref="GI:296147423"
/db_xref="GeneID:855348"
CDS complement(870073..872625)
/gene="YME2"
/locus_tag="YMR302C"
/gene_synonym="PRP12; RNA12"
/note="Integral inner mitochondrial membrane protein with
a role in maintaining mitochondrial nucleoid structure and
number; mutants exhibit an increased rate of mitochondrial
DNA escape; shows some sequence similarity to
exonucleases"
/codon_start=1
/product="Yme2p"
/protein_id="NP_014031.1"
/db_xref="GI:6323960"
/db_xref="SGD:S000004917"
/db_xref="GeneID:855348"
/translation="MLLVRTTSLNVSRMPVPCLARGIGILKGKYRLANLMNAQPSVRH
VSSEIQQKDQQAGESNTATDTGVIHKSDEETLIYFDNVYARTTSVWNPTLWYNLLLRN
QSRDAVREKIRNLASPPNNPIYGLELKSTIPVKRDGGVFATFVVPPKYTKAQVNSLIQ
QNTARESSKNLLSYFTRASAFPVKGSPWIEDLRRLPSTTIVIKFQGPALTEEEIYSLF
RRYGTIIDIFPPTAANNNVAKVRYRSFRGAISAKNCVSGIEIHNTVLHIQYENIRRGH
LVSNFFTNHTRIAIPVLFALLSIFAVLVFDPIREFSIEQKITHKYSLSWDNKFWKQLK
TLTSSTMTSIKYYWGGPDDNHQRKHLWEERIEKVNDLKMWLEENNNTFVVIRGPRGSG
KHDLVMQHTLQNRANVLYLDCDKLIKSRTDPMFLKNAASQLGYFPIFPWIDSVTGVLD
LTVQGLTGQKTGLSETKESRFRNMLTTSLMSIRRIALKNYKAFVSTGDGTVNVKEEDY
LQQHPEAKPVIVIDRFEGKSEINGFVYKELSDWAAMLVQMNIAHVIFLTETVASNQRL
SESLPNQVFKNLILSDASKENSRNYVLSQLEDYLYYNKKSKGENVKEPESEKETAENN
DSDSEADTSVKKAEVILNEKELQEIDASLEPLGGRMLDLQAFVRRVKSGEEPSEAVDK
MIEQASEQITQMFLSDKIDSNKSAQAWELIELLSANPVIPFHEIVNKPLFKAAPETGI
MELENNGLITVSRDRGVLQEIRPAKPLYRAAFTYLINDPELAKVLKTRYLLKVVGFET
GRIKKWEEELKPLGKVPDQKLFKTRLDYLSGKINASNAVITKCEEEIKNLSK"
gene complement(873291..874337)
/gene="ADH2"
/locus_tag="YMR303C"
/gene_synonym="ADR2"
/db_xref="GeneID:855349"
mRNA complement(873291..874337)
/gene="ADH2"
/locus_tag="YMR303C"
/gene_synonym="ADR2"
/product="alcohol dehydrogenase ADH2"
/transcript_id="NM_001182812.1"
/db_xref="GI:296147424"
/db_xref="GeneID:855349"
CDS complement(873291..874337)
/gene="ADH2"
/locus_tag="YMR303C"
/gene_synonym="ADR2"
/EC_number="1.1.1.190"
/EC_number="1.1.1.1"
/note="Glucose-repressible alcohol dehydrogenase II,
catalyzes the conversion of ethanol to acetaldehyde;
involved in the production of certain carboxylate esters;
regulated by ADR1"
/codon_start=1
/product="alcohol dehydrogenase ADH2"
/protein_id="NP_014032.1"
/db_xref="GI:6323961"
/db_xref="SGD:S000004918"
/db_xref="GeneID:855349"
/translation="MSIPETQKAIIFYESNGKLEHKDIPVPKPKPNELLINVKYSGVC
HTDLHAWHGDWPLPTKLPLVGGHEGAGVVVGMGENVKGWKIGDYAGIKWLNGSCMACE
YCELGNESNCPHADLSGYTHDGSFQEYATADAVQAAHIPQGTDLAEVAPILCAGITVY
KALKSANLRAGHWAAISGAAGGLGSLAVQYAKAMGYRVLGIDGGPGKEELFTSLGGEV
FIDFTKEKDIVSAVVKATNGGAHGIINVSVSEAAIEASTRYCRANGTVVLVGLPAGAK
CSSDVFNHVVKSISIVGSYVGNRADTREALDFFARGLVKSPIKVVGLSSLPEIYEKME
KGQIAGRYVVDTSK"
gene 874987..878679
/gene="UBP15"
