LOCUS NC_001146 784333 bp DNA linear PLN 25-FEB-2013
DEFINITION Saccharomyces cerevisiae S288c chromosome XIV, complete sequence.
ACCESSION NC_001146
VERSION NC_001146.8 GI:330443715
DBLINK Project: 128
KEYWORDS TPA:inferential.
SOURCE Saccharomyces cerevisiae S288c
ORGANISM Saccharomyces cerevisiae S288c
Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina;
Saccharomycetes; Saccharomycetales; Saccharomycetaceae;
Saccharomyces.
REFERENCE 1 (bases 1 to 784333)
AUTHORS Philippsen,P., Kleine,K., Pohlmann,R., Dusterhoft,A., Hamberg,K.,
Hegemann,J.H., Obermaier,B., Urrestarazu,L.A., Aert,R.,
Albermann,K., Altmann,R., Andre,B., Baladron,V., Ballesta,J.P.,
Becam,A.M., Beinhauer,J., Boskovic,J., Buitrago,M.J., Bussereau,F.,
Coster,F., Crouzet,M., D'Angelo,M., Dal Pero,F., De Antoni,A.,
Hani,J. et al.
TITLE The nucleotide sequence of Saccharomyces cerevisiae chromosome XIV
and its evolutionary implications
JOURNAL Nature 387 (6632 SUPPL), 93-98 (1997)
PUBMED 9169873
REFERENCE 2 (bases 1 to 784333)
AUTHORS Goffeau,A., Barrell,B.G., Bussey,H., Davis,R.W., Dujon,B.,
Feldmann,H., Galibert,F., Hoheisel,J.D., Jacq,C., Johnston,M.,
Louis,E.J., Mewes,H.W., Murakami,Y., Philippsen,P., Tettelin,H. and
Oliver,S.G.
TITLE Life with 6000 genes
JOURNAL Science 274 (5287), 546 (1996)
PUBMED 8849441
REFERENCE 3 (bases 1 to 784333)
CONSRTM NCBI Genome Project
TITLE Direct Submission
JOURNAL Submitted (14-FEB-2013) National Center for Biotechnology
Information, NIH, Bethesda, MD 20894, USA
REFERENCE 4 (bases 1 to 784333)
CONSRTM Saccharomyces Genome Database
TITLE Direct Submission
JOURNAL Submitted (04-MAY-2012) Department of Genetics, Stanford
University, CA, Stanford 94305-5120, USA
REMARK Protein update by submitter
REFERENCE 5 (bases 1 to 784333)
CONSRTM Saccharomyces Genome Database
TITLE Direct Submission
JOURNAL Submitted (31-MAR-2011) Department of Genetics, Stanford
University, CA, Stanford 94305-5120, USA
REMARK Sequence update by submitter
REFERENCE 6 (bases 1 to 784333)
CONSRTM Saccharomyces Genome Database
TITLE Direct Submission
JOURNAL Submitted (26-MAY-2010) Department of Genetics, Stanford
University, CA, Stanford 94305-5120, USA
REMARK Sequence update by submitter
REFERENCE 7 (bases 1 to 784333)
CONSRTM Saccharomyces Genome Database
TITLE Direct Submission
JOURNAL Submitted (14-DEC-2009) Department of Genetics, Stanford
University, CA, Stanford 94305-5120, USA
COMMENT PROVISIONAL REFSEQ: This record has not yet been subject to final
NCBI review. The reference sequence is identical to BK006947.
On Apr 26, 2011 this sequence version replaced gi:296147840.
Sequence assembly version R64-1-1.
COMPLETENESS: full length.
PRIMARY REFSEQ_SPAN PRIMARY_IDENTIFIER PRIMARY_SPAN COMP
1-6560 Z71615.1 1-6560
3203-7164 Z71614.1 1-3962
6692-8329 Z71613.1 1-1638
7391-11451 Z71612.1 1-4061
9476-12207 Z71611.1 1-2732
12130-13266 Z71610.1 1-1137
12877-14831 Z71609.1 1-1955
13992-16117 Z71608.1 1-2126
15855-18000 Z71607.1 1-2146
17249-19540 Z71606.1 1-2292
18699-22833 Z71605.1 1-4135
22634-24047 Z71604.1 1-1413
23275-27336 Z71603.1 1-4061
27174-28738 Z71602.1 1-1565
28348-31943 Z71601.1 1-3596
31446-33293 Z71599.1 1-1848
33189-34695 Z71598.1 1-1507
34236-37699 Z71597.1 1-3464
37423-38641 Z71596.1 1-1219
38555-40618 Z71595.1 1-2064
40330-42070 Z71593.1 1-1741
42017-43323 Z71592.1 1-1307
43178-44446 Z71591.1 1-1269
44281-45307 Z71590.1 1-1027
45215-48286 Z71589.1 1-3072
47023-49396 Z71588.1 1-2374
49217-51906 Z71587.1 1-2690
51689-52544 Z71586.1 1-856
52525-54121 Z71585.1 1-1597
53925-56445 Z71584.1 1-2522
55898-58154 Z71583.1 1-2258
57523-58897 Z71582.1 1-1375
58809-60482 Z71581.1 1-1673
59792-61957 Z71580.1 1-2165
61858-63569 Z71578.1 1-1712
62944-65743 Z71577.1 1-2800
64563-66516 Z71576.1 1-1954
66053-68914 Z71575.1 1-2861
68396-71672 Z71574.1 1-3277
71444-76945 Z71573.1 1-5502
76588-78658 Z71571.1 1-2071
78521-80639 Z71570.1 1-2119
80261-82805 Z71569.1 1-2545
82542-84168 Z71568.1 1-1627
84018-86217 Z71567.1 1-2200
85154-87896 Z71566.1 1-2743
87241-90302 Z71565.1 1-3062
88737-91993 Z71564.1 1-3257
91425-95222 Z71563.1 1-3798
94802-96172 Z71562.1 1-1371
96081-103133 Z71561.1 1-7053
96313-105183 Z71560.1 1-8871
96313-105183 Z71560.1 1-8871
104103-107686 Z71559.1 1-3584
106696-108466 Z71558.1 1-1771
108275-109094 Z71557.1 1-820
108929-110916 Z71556.1 1-1988
110412-113270 Z71555.1 1-2859
112903-117348 Z71554.1 1-4446
116454-119267 Z71553.1 1-2814
118827-121117 Z71551.1 1-2291
120999-122882 Z71550.1 1-1884
122171-126804 Z71549.1 1-4634
126600-129521 Z71548.1 1-2923
129085-135939 Z71547.1 1-6856
130725-137698 Z71546.1 1-6974
137662-138549 Z71545.1 1-888
138095-140877 Z71544.1 1-2783
140386-144244 Z71543.1 1-3859
144079-145562 Z71542.1 1-1484
145282-146895 Z71540.1 1-1614
146616-148211 Z71539.1 1-1596
147841-155099 Z71538.1 1-7259
154881-156858 Z71537.1 1-1978
156540-157643 Z71536.1 1-1104
157456-158108 Z71535.1 1-653
157866-160630 Z71534.1 1-2765
160374-164502 Z71533.1 1-4129
164321-167328 Z71532.1 1-3008
167098-168042 Z71531.1 1-945
167791-170017 Z71530.1 1-2227
169249-171440 Z71529.1 1-2192
171287-172587 Z71528.1 1-1301
172287-175409 Z71527.1 1-3123
174316-179393 Z71526.1 1-5078
179349-181360 Z71525.1 1-2012
181023-182874 Z71524.1 1-1852
182609-185459 Z71523.1 1-2851
185179-187169 Z71522.1 1-1991
186886-188050 Z71520.1 1-1165
187497-191323 Z71519.1 1-3827
190507-196425 Z71518.1 1-5919
196103-198501 Z71517.1 1-2399
197944-200481 Z71516.1 1-2538
199978-202427 Z71515.1 1-2450
201934-205187 Z71514.1 1-3254
204873-206929 Z71513.1 1-2057
206568-210232 Z71512.1 1-3665
209980-211921 Z71510.1 1-1942
211514-214922 Z71509.1 1-3409
214601-215986 Z71508.1 1-1386
215802-217522 Z71507.1 1-1721
217043-219136 Z71506.1 1-2094
218663-220644 Z71505.1 1-1982
220202-222723 Z71504.1 1-2522
222650-224795 Z71501.1 1-2146
224470-227333 Z71500.1 1-2864
227100-229093 Z71499.1 1-1994
228855-231067 Z71498.1 1-2213
229715-234412 Z71497.1 1-4698
233696-235995 Z71496.1 1-2300
235715-238237 Z71495.1 1-2523
237664-240330 Z71494.1 1-2667
238583-241688 Z71493.1 1-3106
241312-244467 Z71492.1 1-3156
244173-245616 Z71491.1 1-1444
245431-246459 Z71490.1 1-1029
246217-247460 Z71489.1 1-1244
247105-250054 Z71488.1 1-2950
249810-250930 Z71487.1 1-1121
250316-252058 Z71486.1 1-1743
251744-254417 Z71485.1 1-2674
253901-255352 Z71484.1 1-1450
255035-256787 Z71483.1 1-1753
256631-259438 Z71482.1 1-2808
259278-260626 Z71479.1 1-1349
260457-263712 Z71477.1 1-3256
263204-264925 Z71476.1 1-1722
264454-267607 Z71475.1 1-3154
266817-270274 Z71473.1 1-3458
269594-271575 Z71472.1 1-1982
271172-272709 Z71471.1 1-1537
271936-274367 Z71470.1 1-2432
273616-276501 Z71469.1 1-2886
276045-280431 Z71468.1 1-4387
279898-282394 Z71467.1 1-2497
281506-284259 Z71466.1 1-2754
283010-286307 Z71465.1 1-3298
285889-287993 Z71464.1 1-2106
287610-289497 Z71463.1 1-1889
289068-292192 Z71462.1 1-3125
291877-293136 Z71461.1 1-1260
292884-295959 Z71459.1 1-3076
295510-298334 Z71458.1 1-2825
297628-299661 Z71457.1 1-2034
299559-300665 Z71456.1 1-1107
300650-302679 Z71455.1 1-2030
301104-303685 Z71454.1 1-2582
303403-305069 Z71453.1 1-1667
304616-307400 Z71452.1 1-2785
306981-308956 Z71451.1 1-1976
308647-310635 Z71449.1 1-1989
310058-318029 Z71448.1 1-7972
317149-319415 Z71444.1 1-2267
318810-322218 Z71443.1 1-3409
321360-323831 Z71442.1 1-2472
323566-325264 Z71441.1 1-1699
325053-326740 Z71440.1 1-1688
326321-331321 Z71439.1 1-5001
330074-332596 Z71438.1 1-2523
332155-336544 Z71437.1 1-4390
334868-338477 Z71436.1 1-3610
337610-339611 Z71435.1 1-2002
339348-340351 Z71434.1 1-1004
340209-341068 Z71433.1 1-860
340859-342515 Z71432.1 1-1657
341969-343635 Z71431.1 1-1667
343341-345668 Z71430.1 1-2328
345277-346312 Z71429.1 1-1036
346059-347765 Z71428.1 1-1707
347543-349250 Z71427.1 1-1708
348522-349906 Z71426.1 1-1385
349560-350939 Z71424.1 1-1380
350672-351714 Z71423.1 1-1043
351384-352413 Z71422.1 1-1030
352018-352819 Z71421.1 1-802
352531-356793 Z71420.1 1-4263
355043-357452 Z71419.1 1-2410
357187-359595 Z71418.1 1-2409
358953-360916 Z71417.1 1-1964
360640-366740 Z71416.1 1-6101
365718-368594 Z71414.1 1-2877
368322-370367 Z71413.1 1-2046
370056-371881 Z71412.1 1-1826
371646-372450 Z71411.1 1-805
372227-374170 Z71410.1 1-1944
373582-375320 Z71409.1 1-1739
374693-378766 Z71408.1 1-4074
378492-379557 Z71407.1 1-1066
379226-381479 Z71406.1 1-2254
381160-382358 Z71405.1 1-1199
382203-383986 Z71404.1 1-1784
383664-387226 Z71403.1 1-3563
384060-390145 Z71402.1 1-6086
389768-392891 Z71401.1 1-3124
392168-394684 Z71400.1 1-2517
394371-398022 Z71399.1 1-3652
397679-398683 Z71398.1 1-1005
398371-401032 Z71397.1 1-2662
400538-402651 Z71396.1 1-2114
402522-406357 Z71394.1 1-3836
405565-408340 Z71393.1 1-2776
408023-410118 Z71392.1 1-2096
409910-412683 Z71391.1 1-2774
412054-413638 Z71390.1 1-1585
413200-416939 Z71388.1 1-3740
416282-417825 Z71387.1 1-1544
417303-418963 Z71386.1 1-1661
418489-420097 Z71385.1 1-1609
419827-420943 Z71383.1 1-1117
420779-424894 Z71382.1 1-4116
424584-427734 Z71380.1 1-3151
426755-430086 Z71379.1 1-3332
429754-434998 Z71378.1 1-5245
434494-437612 Z71377.1 1-3119
437141-438566 Z71376.1 1-1426
438318-439601 Z71375.1 1-1284
439284-441365 Z71374.1 1-2082
440571-443397 Z71373.1 1-2827
442359-444911 Z71372.1 1-2553
444316-447610 Z71371.1 1-3295
446841-449867 Z71370.1 1-3027
449375-450870 Z71369.1 1-1496
450531-452407 Z71368.1 1-1877
452074-456564 Z71367.1 1-4491
456131-457703 Z71366.1 1-1573
457170-462410 Z71364.1 1-5241
461991-466333 Z71363.1 1-4343
465948-467130 Z71362.1 1-1183
466643-470052 Z71361.1 1-3410
468834-471376 Z71360.1 1-2543
471103-473297 Z71359.1 1-2195
473298-476931 Z71357.1 1-3634
476620-478565 Z71356.1 1-1946
478033-479767 Z71355.1 1-1735
479166-481390 Z71354.1 1-2225
480992-483555 Z71353.1 1-2564
482978-485606 Z71352.1 1-2629
485311-486765 Z71351.1 1-1455
486480-488385 Z71350.1 1-1906
488125-490316 Z71349.1 1-2192
490117-491522 Z71348.1 1-1406
491241-493365 Z71347.1 1-2125
492972-493955 Z71346.1 1-984
493549-495700 Z71345.1 1-2152
495002-499680 Z71344.1 1-4679
496970-501514 Z71343.1 1-4545
500257-503723 Z71342.1 1-3467
502778-505867 Z71341.1 1-3089
505485-507757 Z71340.1 1-2272
507098-508775 Z71339.1 1-1678
508703-510539 Z71338.1 1-1837
510213-512667 Z71337.1 1-2455
512422-515762 Z71335.1 1-3341
514936-517248 Z71334.1 1-2313
516736-517993 Z71332.1 1-1258
517843-526085 Z71331.1 1-8243
518846-529941 Z71330.1 1-11096
529584-531724 Z71329.1 1-2141
531412-532658 Z71328.1 1-1247
532187-534078 Z71327.1 1-1892
533871-535280 Z71326.1 1-1410
534983-538172 Z71325.1 1-3190
536279-539910 Z71324.1 1-3632
539820-542303 Z71323.1 1-2484
541882-542962 Z71322.1 1-1081
542823-545400 Z71321.1 1-2578
544979-548099 Z71320.1 1-3121
545910-549467 Z71318.1 1-3558
549291-553379 Z71317.1 1-4089
551988-555047 Z71316.1 1-3060
554751-557019 Z71315.1 1-2269
556833-557919 Z71314.1 1-1087
557659-559813 Z71313.1 1-2155
559003-568521 Z71312.1 1-9519
560480-570476 Z71311.1 1-9997
569692-572998 Z71310.1 1-3307
572316-574505 Z71309.1 1-2190
573854-575639 Z71308.1 1-1786
575352-576726 Z71307.1 1-1375
575862-577204 Z71306.1 1-1343
577039-579579 Z71305.1 1-2541
578997-581919 Z71303.1 1-2923
581617-584319 Z71302.1 1-2703
583375-587106 Z71301.1 1-3732
585292-588262 Z71300.1 1-2971
587848-591426 Z71299.1 1-3579
591161-593226 Z71298.1 1-2066
592900-595622 Z71297.1 1-2723
595348-598375 Z71296.1 1-3028
597540-599935 Z71295.1 1-2396
599231-602137 Z71294.1 1-2907
601775-602906 Z71293.1 1-1132
602386-605383 Z71292.1 1-2998
604269-606318 Z71291.1 1-2050
605612-610054 Z71290.1 1-4443
609511-611835 Z71288.1 1-2325
611666-613634 Z71287.1 1-1969
613171-614820 Z71286.1 1-1650
614361-616210 Z71285.1 1-1850
616084-618506 Z71284.1 1-2424
617109-620066 Z71283.1 1-2959
619566-621312 Z71282.1 1-1747
620979-623331 Z71281.1 1-2353
622429-624974 Z71280.1 1-2546
624622-626173 Z71279.1 1-1552
625830-627455 Z71278.1 1-1626
627143-629621 Z71277.1 1-2479
628617-633007 Z71616.1 1-4391
631062-634343 Z71617.1 1-3282
633857-635942 Z71618.1 1-2086
635298-636930 Z71619.1 1-1633
636384-639181 Z71620.1 1-2798
638855-640395 Z71622.1 1-1541
640115-642689 Z71623.1 1-2575
642382-643743 Z71624.1 1-1362
643440-644319 Z71625.1 1-880
644194-647431 Z71626.1 1-3238
646951-649027 Z71627.1 1-2077
648938-652464 Z71628.1 1-3527
650833-653386 Z71629.1 1-2554
653104-654672 Z71630.1 1-1569
654392-662912 Z71631.1 1-8521
661375-664269 Z71632.1 1-2895
663582-665338 Z71633.1 1-1757
664945-667409 Z71634.1 1-2465
667268-668376 Z71635.1 1-1109
668223-669773 Z71636.1 1-1551
669592-670417 Z71637.1 1-826
670194-672408 Z71638.1 1-2215
672119-673273 Z71639.1 1-1155
673062-674922 Z71641.1 1-1861
674690-676176 Z71642.1 1-1487
675877-677198 Z71643.1 1-1322
677104-678798 Z71644.1 1-1695
678489-680693 Z71645.1 1-2205
680455-686009 Z71646.1 1-5555
685434-687634 Z71647.1 1-2201
687117-690320 Z71648.1 1-3204
689999-693018 Z71649.1 1-3020
691287-694360 Z71650.1 1-3074
694048-695051 Z71651.1 1-1004
694823-695594 Z71652.1 1-772
695328-697613 Z71653.1 1-2286
697485-699689 Z71654.1 1-2205
699432-700540 Z71655.1 1-1109
700461-701894 Z71656.1 1-1434
701667-703698 Z71658.1 1-2032
703086-706138 Z71659.1 1-3053
705877-707787 Z71660.1 1-1911
707609-708522 Z71661.1 1-914
708196-711629 Z71662.1 1-3434
711205-713022 Z71663.1 1-1818
712812-714047 Z71664.1 1-1236
713656-716779 Z71665.1 1-3124
715389-719345 Z71666.1 1-3957
718328-721119 Z71667.1 1-2792
720648-723355 Z71668.1 1-2707
723113-728425 Z71669.1 1-5313
724307-731617 Z71670.1 1-7310
729271-733355 Z71671.1 1-4084
733304-734290 Z71672.1 1-987
734070-736802 Z71673.1 1-2733
735734-739950 Z71674.1 1-4217
738546-742880 Z71675.1 1-4335
742111-744359 Z71676.1 1-2249
743541-746942 Z71677.1 1-3402
745344-749135 Z71678.1 1-3792
748767-750349 Z71679.1 1-1583
750009-753724 Z71680.1 1-3716
753701-755745 Z71681.1 1-2045
755036-760066 Z71682.1 1-5031
759100-761122 Z71683.1 1-2023
760886-765374 Z71684.1 1-4489
764978-772656 Z71686.1 1-7679
771469-774791 Z71687.1 1-3323
774352-777601 Z71688.1 1-3250
774985-779915 Z71689.1 1-4931
778739-781917 Z71690.1 1-3179
781041-783286 Z71691.1 1-2246
782281-784333 Z71692.1 1-2053
782281-784333 Z71692.1 1-2053
FEATURES Location/Qualifiers
source 1..784333
/organism="Saccharomyces cerevisiae S288c"
/mol_type="genomic DNA"
/strain="S288c"
/db_xref="taxon:559292"
/chromosome="XIV"
telomere complement(1..7428)
/note="TEL14L; Telomeric region on the left arm of
Chromosome XIV, composed of an X element core sequence, X
element combinatorial repeats, a short stretch of
telomeric repeats, and a long Y' element"
/db_xref="SGD:S000028924"
repeat_region complement(1..6617)
/note="TEL14L-YP; Telomeric long Y' element on the left
arm of Chromosome XIV; contains an ARS consensus sequence,
a region of 36-bp repeats, and three ORFs (YRF1-6/YNL339C,
YNL339W-A, YNL339W-B)"
/rpt_family="Y' element"
/db_xref="SGD:S000028928"
gene complement(371..6098)
/gene="YRF1-6"
/locus_tag="YNL339C"
/gene_synonym="YRF1"
/db_xref="GeneID:855377"
mRNA complement(join(371..5931,6080..6098))
/gene="YRF1-6"
/locus_tag="YNL339C"
/gene_synonym="YRF1"
/product="Y' element ATP-dependent helicase protein 1 copy
6"
/transcript_id="NM_001183177.1"
/db_xref="GI:296147446"
/db_xref="GeneID:855377"
CDS complement(join(371..5931,6080..6098))
/gene="YRF1-6"
/locus_tag="YNL339C"
/gene_synonym="YRF1"
/EC_number="3.6.1.-"
/note="Helicase encoded by the Y' element of subtelomeric
regions, highly expressed in the mutants lacking the
telomerase component TLC1; potentially phosphorylated by
Cdc28p"
/codon_start=1
/product="Y' element ATP-dependent helicase protein 1 copy
6"
/protein_id="NP_014060.1"
/db_xref="GI:6323990"
/db_xref="SGD:S000005283"
/db_xref="GeneID:855377"
/translation="MEIENEQICTCIAQILHLLNSLIITFLDDDKTETGQSFVYIDGF
LVKKHNNQHTIVNFETYKNKMKVSDRRKFEKANFDEFESALNNKNDLVHCPSITLFES
IPTEVRSFYEDEKSGLIKVVKFRTGAMDRKRSFEKIVVSVMVGKNVQKFLTFVEDEPD
FQGGPIPSKYLIPKKINLMVYTLFQVHTLKFNRKDYDTLSLFYLNRGYYNELSFRVLE
RCYEIASARPNDSSTMRTFTDFVSGTPIVRGLQKSTIRKYGYNLAPYMFLLLHVDELS
IFSAYQASLPGEKKVDTERLKRDLCPRKPTEIKYFSQICNDMMNKKDRLGDILHIILR
ACALNFGAGPRGGAGDEEDRSITNEEPIIPSVDEHGLKVCKLRSPNTPRRLRKTLDAV
KALLVSSCACTARDLDIFDDNNGVAMWKWIKILYHEVAQETALKDSYRITLVPSSDGV
SVCGKLFNREYVRGFYFACKAQFDNLWEELNDCFYMPTVVDIASLILRNREVLFREPK
RGIDEYLENDSFLQMIPVKYREIVLPKLRRDTNKMTAALKNKVTVAIDELTVPLMWMI
HFAVGYPYRYPELQLLAFAGPQRNVYVDDTTRRIQLYTDYNKNGSSEPRLKTLDGLTS
DYVFYFVTVLRQMQICALGNSYDAFNHDPWMDVVGFEDPDQVTNRDISRIVLYSYMFL
NTAKGCLVEYATFRQYMRELPKNAPQKLNFREMRQGLIALGRHCVGSRFETDLYESAT
SELMANHSVQTGRNIYGVDSFSLTSVSGTTATLLQERASERWIQWLGLESDYHCSFSS
TRNAEDVVAGEAASSDHHQKISRVTRKRPREPKSTNDILVAGQKLFGSSFEFRDLHQL
RLCHEIYMADTPSVAVQAPPGYGKTELFHLPLIALASKGDVKYVSFLFVPYTVLLANC
MIRLSRCGCLNVAPVRNFIEEGCDGVTDLYVGIYDDLASTNFTDRIAAWENIVECTFR
TNNVKLGYLIVDEFHNFETEVYRQSQFGGITNLDFDAFEKAIFLSGTAPEAVADAALQ
RIGLTGLAKKSMDINELKRSEDLSRGLSSYPTRMFNLIKEKSEVPLGHVHKIWKKVES
QPEEALKLLLALFEIEPESKAIVVASTTNEVEELACSWRKYFRVVWIHGKLGAAEKVS
RTKEFVTDGSMRVLIGTKLVTEGIDIKQLMMVIMLDNRLNIIELIQGVGRLRDGGLCY
LLSRKNSWAARNRKGELPPIKEGCITEQVREFYGLESKKGKKGQHVGCCGSRTDLSAD
TVELIERMDRLAEKQATASMSIVALPSSFQESNSSDRCRKYCSSDEDSDTCIHGSANA
STNATTNSSTNATTTASTNVRTSATTTASINVRTSATTTESTNSSTNATTTASTNVRT
SATTTASINVRTSATTTESTNSNTSATTTESTDSNTSATTTESTDSNTSATTTASTNS
STNATTTASTNSSTNATTTESTNASAKEDANKDGNAEDNRFHPVTDINKESYKRKGSQ
MVLLERKKLKAQFPNTSENMNVLQFLGFRSDEIKHLFLYGIDVYFCPEGVFTQYGLCK
GCQKMFELCVCWAGQKVSYRRMAWEALAVERMLRNDEEYKEYLEDIEPYHGDPVGYLK
FFSVKRGEIYSQIQRNYAWYLAITRRRETISVLDSTRGKQGSQVFRMSGRQIKELYYK
VWSNLRESKTEVLQYFLNWDEKKCREEWEAKDDTVFVEALEKVGVFQRLRSMTSAGLQ
GPQYVKLQFSRHHRQLRSRYELSLGMHLRDQLALGVTPSKVPHWTAFLSMLIGLFCNK
TFRQKLEYLLEQISEVWLLPHWLDLANVEVLAADNTRVPLYMLMVAVHKELDSDDVPD
GRFDILLCRDSSREVGE"
repeat_region complement(6618..6691)
/note="TEL14L-TR; Internal stretch of telomeric repeats
spanning ORF YNL338W on the left arm of Chromosome XIV"
/rpt_family="Telomeric Repeat"
/db_xref="SGD:S000028925"
repeat_region complement(6692..6963)
/note="TEL14L-XR; Telomeric X element combinatorial Repeat
region on the left arm of Chromosome XIV; contains repeats
of the D, C, B and A types, as well as Tbf1p binding
sites; formerly called SubTelomeric Repeats"
/rpt_family="X element Combinatorial Repeats"
/db_xref="SGD:S000028927"
repeat_region complement(6964..7428)
/note="TEL14L-XC; Telomeric X element Core sequence on the
left arm of Chromosome XIV; contains an ARS consensus
sequence, an Abf1p binding site consensus sequence, and
ORF YNL337W"
/rpt_family="X element Core sequence"
/db_xref="SGD:S000028926"
gene 8330..9475
/gene="COS1"
/locus_tag="YNL336W"
/db_xref="GeneID:855380"
mRNA 8330..9475
/gene="COS1"
/locus_tag="YNL336W"
/product="Cos1p"
/transcript_id="NM_001183174.1"
/db_xref="GI:296147447"
/db_xref="GeneID:855380"
CDS 8330..9475
/gene="COS1"
/locus_tag="YNL336W"
/note="hypothetical protein, member of the DUP380
subfamily of conserved, often subtelomerically-encoded
proteins"
/codon_start=1
/product="Cos1p"
/protein_id="NP_014063.1"
/db_xref="GI:6323993"
/db_xref="SGD:S000005280"
/db_xref="GeneID:855380"
/translation="MKENELKNEKSVDVLSFKQLESQKIVLPQDLFRSSFTWFCYEIY
KSLAFRIWMLLWLPLSVWWKLSNNCIYPLIVSLLVLFLGPIFVLVICGLSRKRSLSKQ
LIQFCKEVTENTPSSDPHDWEVVAANLNSYLYENKAWNTKYFFFNAMVCQEAFRTTLL
EPFSLKKDEAAKVKSFKDSVPYIEEALGVYFREVEKQWKLFNSEKSWSPVGLEDAKLP
KEAYRFKLTWFLKRISNIFMLIPFLNFLCCIYVSRGMCLLLRTFYLGWILFMLVQGFQ
NMRMIVLSVKMEHKMQFLSTIINEQESGANGWDEIAKKMNRYLFEKKVWKNEEFFFDG
IDCEWFFSHFFYRVLSAKKSMRALSLNVELWPYIKEAQLSCSEESLA"
gene 11452..12129
/gene="DDI3"
/locus_tag="YNL335W"
/db_xref="GeneID:855381"
mRNA 11452..12129
/gene="DDI3"
/locus_tag="YNL335W"
/product="Ddi3p"
/transcript_id="NM_001183173.1"
/db_xref="GI:296147448"
/db_xref="GeneID:855381"
CDS 11452..12129
/gene="DDI3"
/locus_tag="YNL335W"
/note="hypothetical protein; expression is induced over
100-fold by DNA damage; induction decreased in rad6 and
rad18 mutants"
/codon_start=1
/product="Ddi3p"
/protein_id="NP_014064.1"
/db_xref="GI:6323994"
/db_xref="SGD:S000005279"
/db_xref="GeneID:855381"
/translation="MSQYGFVRVPREVEKAIPVVNAPRPRAVVPPPNSETARLVREYA
AKELTAPVLNHSLRVFQYSVAIIRDQFPAWDLDQEVLYVTCLLHDIATTDKNMRATKM
SFEYYGGILSRELVFNATGGNQDYADAVTEAIIRHQDLTGTGYITTLGLILQIATTLD
NVGSNTDLIHIDTVSAINEQFPRLHWLSCFATVVDTENSRKPWGHTSSLGDDFSKKVI
CNTFGYN"
gene complement(12208..12876)
/gene="SNO2"
/locus_tag="YNL334C"
/db_xref="GeneID:855382"
mRNA complement(12208..12876)
/gene="SNO2"
/locus_tag="YNL334C"
/product="Sno2p"
/transcript_id="NM_001183172.1"
/db_xref="GI:296147449"
/db_xref="GeneID:855382"
CDS complement(12208..12876)
/gene="SNO2"
/locus_tag="YNL334C"
/EC_number="2.6.-.-"
/note="hypothetical protein, nearly identical to Sno3p;
expression is induced before the diauxic shift and also in
the absence of thiamin"
/codon_start=1
/product="Sno2p"
/protein_id="NP_014065.1"
/db_xref="GI:6323995"
/db_xref="SGD:S000005278"
/db_xref="GeneID:855382"
/translation="MTVVIGVLALQGAFIEHVRHVEKCIVENRDFYEKKLSVMTVKDK
NQLAQCDALIIPGGESTAMSLIAERTGFYDDLYAFVHNPSKVTWGTCAGMIYISQQLS
NEEKLVKTLNLLKVKVKRNAFGRQAQSSTRICDFSNFIPHCNDFPATFIRAPVIEEVL
DPEHVQVLYKLDGKDNGGQELIVAAKQKNNILATSFHPELAENDIRFHDWFIREFVLK
NYSK"
gene 13267..14163
/gene="SNZ2"
/locus_tag="YNL333W"
/db_xref="GeneID:855383"
mRNA 13267..14163
/gene="SNZ2"
/locus_tag="YNL333W"
/product="Snz2p"
/transcript_id="NM_001183171.1"
/db_xref="GI:296147450"
/db_xref="GeneID:855383"
CDS 13267..14163
/gene="SNZ2"
/locus_tag="YNL333W"
/note="Member of a stationary phase-induced gene family;
transcription of SNZ2 is induced prior to diauxic shift,
and also in the absence of thiamin in a Thi2p-dependent
manner; forms a coregulated gene pair with SNO2; interacts
with Thi11p"
/codon_start=1
/product="Snz2p"
/protein_id="NP_014066.1"
/db_xref="GI:6323996"
/db_xref="SGD:S000005277"
/db_xref="GeneID:855383"
/translation="MSEFKVKTGLAQMLKGGVIMDVVTPEQAIIAERAGACAVMALER
IPADMRKSGQVCRMSDPRMIKEIMEAVSIPVMAKVRIGHFVEAQILEELQVDYIDESE
VLTPADWTHHIEKHNFKVPFVCGAKDLGEALRRINEGAAMIRTKGEAGTGDVSEAVKH
ITKIKAEIQQYKENLKTESDFAAKATELRVPVDLLKTTLSEGKLPVVNFAAGGVATPA
DAALLMQLGCEGVFVGSGIFKSSDPEKLACAIVEATTHYDNPAKLLQISSDLGDLMGG
ISIQSINEAGGKNGARLSEIGW"
gene 14832..15854
/gene="THI12"
/locus_tag="YNL332W"
/db_xref="GeneID:855384"
mRNA 14832..15854
/gene="THI12"
/locus_tag="YNL332W"
/product="Thi12p"
/transcript_id="NM_001183170.1"
/db_xref="GI:296147451"
/db_xref="GeneID:855384"
CDS 14832..15854
/gene="THI12"
/locus_tag="YNL332W"
/note="Protein involved in synthesis of the thiamine
precursor hydroxymethylpyrimidine (HMP); member of a
subtelomeric gene family including THI5, THI11, THI12, and
THI13"
/codon_start=1
/product="Thi12p"
/protein_id="NP_014067.1"
/db_xref="GI:6323997"
/db_xref="SGD:S000005276"
/db_xref="GeneID:855384"
/translation="MSTDKITFLLNWQPTPYHIPIFLAQTKGYFKEQGLDMAILEPTN
PSDVTELIGSGKVDMGLKAMIHTLAAKARGFPVTSVASLLDEPFTGVLYLKGSGITED
FQSLKGKKIGYVGEFGKIQIDELTKHYGMKPEDYTAVRCGMNVAKYIIEGKIDAGIGI
ECMQQVELEEYLAKQGRPASDAKMLRIDKLACLGCCCFCTVLYICNDEFLKKNPEKVR
KFLKAIKKATDYVLADPVKAWKEYIDFKPRLNNDLSYKQYQRCYAYFSSSLYNVHRDW
KKVTGYGKRLAILPPDYVSNYTNEYLSWPEPEEVSDPLEAQRLMAIHQEKCRQEGTFK
RLALPA"
gene complement(16118..17248)
/gene="AAD14"
/locus_tag="YNL331C"
/db_xref="GeneID:855385"
mRNA complement(16118..17248)
/gene="AAD14"
/locus_tag="YNL331C"
/product="Aad14p"
/transcript_id="NM_001183169.1"
/db_xref="GI:296147452"
/db_xref="GeneID:855385"
CDS complement(16118..17248)
/gene="AAD14"
/locus_tag="YNL331C"
/EC_number="1.1.1.-"
/note="Putative aryl-alcohol dehydrogenase; similar to P.
chrysosporium aryl-alcohol dehydrogenase; mutational
analysis has not yet revealed a physiological role"
/codon_start=1
/product="Aad14p"
/protein_id="NP_014068.1"
/db_xref="GI:6323998"
/db_xref="SGD:S000005275"
/db_xref="GeneID:855385"
/translation="MTDLFKPLPEPPTELGRLRVLSKTAGIRVSPLILGGASIGDAWS
GFMGSMNKEQAFELLDAFYEAGGNCIDTANSYQNEESEIWIGEWMASRKLRDQIVIAT
KFTGDYKKYEVGGGKSANYCGNHKRSLHVSVRDSLRKLQTDWIDILYIHWWDYMSSIE
EVMDSLHILVQQGKVLYLGVSDTPAWVVSAANYYATSHGKTPFSVYQGKWNVLNRDFE
RDIIPMARHFGMALAPWDVMGGGRFQSKKAMEERKKNGEGLRTFVGGPEQTELEVKIS
EALTKIAEEHGTESVTAIAIAYVRSKAKNVFPLIGGRKIEHLKQNIEALSIKLTPEQI
EYLESIVPFDVGFPKSLIGDDPAVTKKLSPLTSMSARIAFDN"
gene complement(18001..19302)
/gene="RPD3"
/locus_tag="YNL330C"
/gene_synonym="MOF6; REC3; SDI2; SDS6"
/db_xref="GeneID:855386"
mRNA complement(18001..19302)
/gene="RPD3"
/locus_tag="YNL330C"
/gene_synonym="MOF6; REC3; SDI2; SDS6"
/product="Rpd3p"
/transcript_id="NM_001183168.1"
/db_xref="GI:296147453"
/db_xref="GeneID:855386"
CDS complement(18001..19302)
/gene="RPD3"
/locus_tag="YNL330C"
/gene_synonym="MOF6; REC3; SDI2; SDS6"
/note="Histone deacetylase; regulates transcription,
silencing, and other processes by influencing chromatin
remodeling; forms at least two different complexes which
have distinct functions and members; Rpd3(L) recruitment
to the subtelomeric region is regulated by interaction
with the arginine methyltransferase, Hmt1p"
/codon_start=1
/product="Rpd3p"
/protein_id="NP_014069.1"
/db_xref="GI:6323999"
/db_xref="SGD:S000005274"
/db_xref="GeneID:855386"
/translation="MVYEATPFDPITVKPSDKRRVAYFYDADVGNYAYGAGHPMKPHR
IRMAHSLIMNYGLYKKMEIYRAKPATKQEMCQFHTDEYIDFLSRVTPDNLEMFKRESV
KFNVGDDCPVFDGLYEYCSISGGGSMEGAARLNRGKCDVAVNYAGGLHHAKKSEASGF
CYLNDIVLGIIELLRYHPRVLYIDIDVHHGDGVEEAFYTTDRVMTCSFHKYGEFFPGT
GELRDIGVGAGKNYAVNVPLRDGIDDATYRSVFEPVIKKIMEWYQPSAVVLQCGGDSL
SGDRLGCFNLSMEGHANCVNYVKSFGIPMMVVGGGGYTMRNVARTWCFETGLLNNVVL
DKDLPYNEYYEYYGPDYKLSVRPSNMFNVNTPEYLDKVMTNIFANLENTKYAPSVQLN
HTPRDAEDLGDVEEDSAEAKDTKGGSQYARDLHVEHDNEFY"
gene complement(19541..22633)
/gene="PEX6"
/locus_tag="YNL329C"
/gene_synonym="PAS8"
/db_xref="GeneID:855387"
mRNA complement(19541..22633)
/gene="PEX6"
/locus_tag="YNL329C"
/gene_synonym="PAS8"
/product="Pex6p"
/transcript_id="NM_001183167.1"
/db_xref="GI:296147454"
/db_xref="GeneID:855387"
CDS complement(19541..22633)
/gene="PEX6"
/locus_tag="YNL329C"
/gene_synonym="PAS8"
/note="AAA-peroxin that heterodimerizes with AAA-peroxin
Pex1p and participates in the recycling of peroxisomal
signal receptor Pex5p from the peroxisomal membrane to the
cystosol"
/codon_start=1
/product="AAA family ATPase peroxin 6"
/protein_id="NP_014070.1"
/db_xref="GI:6324000"
/db_xref="SGD:S000005273"
/db_xref="GeneID:855387"
/translation="MKASLTFSLSGIYAPCSISRDIYLEYGDKKAECLYGTIRLPQYG
PGCTPGKIVHCVLDDSLPFCSIVVPSKLFGFMPTQPTMDFCYFEPILDNVVPVLDSVT
FLINEQLYSKLMDLPQEMQQIQFLHYKYNINSMETVVHSRDILTSGLCQILNCSPFPQ
GLVDFTETQLILVNDTEQKLSALKYANEDEEYALPKIGTNSALSIDLESLPCTISRDL
LRPAPHINDDNSIYAFTDAETLLRLDVTSGSFITVSNMGCVRLVKLFVLLLPNGFKKR
TIYAPPKIIASFPDCSVVTISKSNIGHTDIPIANQVFISRVGGWLQSQKCFQNIILTT
LKKFFSESKRILCQNDLIPIAFDSSMADLNIAEENDESDDEDELGQYYKNDSLVWFFV
TSAELDCFSKDNSHFIIDPNRTKLITTNITNRRPLPLSRSNLQRYYGFAETFYYDLHI
FPYVRQLVNILETSFNCSQRGITLNASVLLHSTTNNVGKATMVRFASKYLGIHLLEID
CLSLTSNSRQLDSTSKIIGYIRAKCENVLPYASPAVIFLAHLDSILLDVNANQDPEAI
KLQKSINFEMSKLLDDFTFKFPGTTFVGSVNNIDNVPSSFRSHMRFEILVPVPSEAQR
LRIFQWYLSSHELNRDVQQKVPVSYMDNISFSSLSSYSAGLTPLDIKSIVETARMTAT
ARFYQESKKCGWLPQSILITQEDLSKATSKARNEFSVSIGAPQIPNVTWDDIGGIDFV
KGEILDTIDMPLKHPELFTSGMKKRSGILFYGPPGTGKTLMAKAIATNFSLNFFSVKG
PELLNMYIGESEANVRRVFQKAREAKPCVIFFDEIDSVAPKRGNQGDSGGVMDRIVSQ
LLAELDGMSTDADGVFVIGATNRPDLLDEALLRPGRFDKLLYLGIPDTDTKQLNILEA
LTRKFVLDNDVKLIELAKLCPFNYTGADFYALCSDAMLNAMSRIARMVEKKVSQHNEL
TGENISTRRWFDKIATKEDTKVVVKMEDFLKAQEQLTPSVSRAELNHYEAVRANFEGA
"
gene complement(22834..23274)
/gene="MDJ2"
/locus_tag="YNL328C"
/db_xref="GeneID:855388"
mRNA complement(22834..23274)
/gene="MDJ2"
/locus_tag="YNL328C"
/product="Mdj2p"
/transcript_id="NM_001183166.1"
/db_xref="GI:296147455"
/db_xref="GeneID:855388"
CDS complement(22834..23274)
/gene="MDJ2"
/locus_tag="YNL328C"
/note="Constituent of the mitochondrial import motor
associated with the presequence translocase; function
overlaps with that of Pam18p; stimulates the ATPase
activity of Ssc1p to drive mitochondrial import; contains
a J domain"
/codon_start=1
/product="Mdj2p"
/protein_id="NP_014071.1"
/db_xref="GI:6324001"
/db_xref="SGD:S000005272"
/db_xref="GeneID:855388"
/translation="MVLPIIIGLGVTMVALSVKSGLNAWTVYKTLSPLTIAKLNNIRI
ENPTAGYRDALKFKSSLIDEELKNRLNQYQGGFAPRMTEPEALLILDISAREINHLDE
KLLKKKHRKAMVRNHPDRGGSPYMAAKINEAKEVLERSVLLRKR"
gene 24048..27173
/gene="EGT2"
/locus_tag="YNL327W"
/db_xref="GeneID:855389"
mRNA 24048..27173
/gene="EGT2"
/locus_tag="YNL327W"
/product="Egt2p"
/transcript_id="NM_001183165.2"
/db_xref="GI:330443689"
/db_xref="GeneID:855389"
CDS 24048..27173
/gene="EGT2"
/locus_tag="YNL327W"
/note="Glycosylphosphatidylinositol (GPI)-anchored cell
wall endoglucanase required for proper cell separation
after cytokinesis, expression is activated by Swi5p and
tightly regulated in a cell cycle-dependent manner"
/codon_start=1
/product="Egt2p"
/protein_id="NP_014072.2"
/db_xref="GI:330443690"
/db_xref="SGD:S000005271"
/db_xref="GeneID:855389"
/translation="MNKLLLHLVRVISILGLANALTQTQPILKDIQITDSYTKTKECT
DPDHWFIIEGQLSIPKGSQQNITFQVPDAFSSFPQEPFSIKHNSNSVATISRPDKSTN
NFTISIPEKSSEDITTTFNFLAQLTSDAKSKVTEPKSIVYSFYSENTMFNDVIDYVAK
NTSAITTDGGIYKTNNTAWFTVDLPMRTFRNPVYLTSQTSSSSDYVFDTSLTKFEVVT
AVDSFNEPINAIPYTTVHDYSTEDEIRCLFNSTISGGLYFRVTYFTKKLSTSSISNTV
ELTYPDEGTSVRLLGKRDTSTTLASELYSESAANIDSTTSDDTTSSDAAITPTYSNST
LSSYTSQSSAIPEVAVTASLSSGILSSTVDGASTSADASMSAVSTVSSSSEQASSSSI
SLSAPSSSNSTFTTPSSSLSATETYSIISSASISVTQASYIDNSTTTAVTQSTSTIAV
SSAEKLSSTLSYTSNVTISVSSATQHTTTPSYVSNSTTLSSSSVLESVISSPYLANTT
VSGASSASQSTNPPYVSNSTTSSATQLATIAPFAINITGTSISSSITNTSSVSSTTSS
LSSGPFVSNTTVASGSYILTTTTESAQLTEIGSLIPISTITTSTTTSGTDKTGSNKVA
SSTEIAQSIVNNSSLSVSTINTNAATAAANARNATFTHATHSGSLQPSYHSSSLLSST
IDTKVTTATTSTSRDGSSSLAFTTGLNQSVVTGTDKSDTYSVISSTESAQVTEYDSLL
PISTLKPTVVTGTSRNSTFSMVSSTKLTEATATDKGDAYSVISSTQSAQVTEYGSMLP
ISTLETPTVIMSTDESGYFTLTTCTESGQATEYGSLIPISTLDGSVIYTFTGESVVVG
YSTTVGAAQYAQHTSLVPVSTIKGSKTSLSTEESVVAGYSTTVGAAQYAQHTSLVPVS
TIKGSKTSLSTEESVVAGYSTTVDSAQYAEHTNLVAIDTLKTSTFQKATATEVCVTCT
ALSSPHSATLDAGTTISLPTSSSTSLSTIITWYSSSTIKPPSISTYSGAAGQLTIRIG
SLLLGLISFLL"
gene complement(27337..28347)
/gene="PFA3"
/locus_tag="YNL326C"
/db_xref="GeneID:855390"
mRNA complement(27337..28347)
/gene="PFA3"
/locus_tag="YNL326C"
/product="Pfa3p"
/transcript_id="NM_001183164.1"
/db_xref="GI:296147457"
/db_xref="GeneID:855390"
CDS complement(27337..28347)
/gene="PFA3"
/locus_tag="YNL326C"
/EC_number="2.3.1.-"
/note="Palmitoyltransferase for Vac8p, required for
vacuolar membrane fusion; contains an
Asp-His-His-Cys-cysteine rich (DHHC-CRD) domain;
autoacylates; required for vacuolar integrity under stress
conditions"
/codon_start=1
/product="Pfa3p"
/protein_id="NP_014073.1"
/db_xref="GI:6324003"
/db_xref="SGD:S000005270"
/db_xref="GeneID:855390"
/translation="MNDRLSLTSLFPRCLTTCLYIWTAYITLTRIHQIPRWFLALTIV
PTLAVALYTYYKVIARGPGSPLDFPDLLVHDLKAAENGLELPPEYMSKRCLTLKHDGR
FRVCQVCHVWKPDRCHHCSSCDVCILKMDHHCPWFAECTGFRNQKFFIQFLMYTTLYA
FLVLIYTCYELGTWFNSGSFNRELIDFHLLGVALLAVAVFISVLAFTCFSIYQVCKNQ
TTIEVHGMRRYRRDLEILNDSYGTNEHLENIFDLGSSMANWQDIMGTSWLEWILPIET
FKYKKSKHTKDEKGLYFNVRPQVQDRLLSSRCLEDQLLRRVTPRPSLEADRASVEIID
AN"
rep_origin 28469..28700
/note="ARS1405;
Autonomously Replicating Sequence"
/db_xref="SGD:S000118382"
gene complement(28739..31378)
/gene="FIG4"
/locus_tag="YNL325C"
/db_xref="GeneID:855392"
mRNA complement(28739..31378)
/gene="FIG4"
/locus_tag="YNL325C"
/product="phosphatidylinositol-3,5-bisphosphate
5-phosphatase"
/transcript_id="NM_001183163.1"
/db_xref="GI:296147458"
/db_xref="GeneID:855392"
CDS complement(28739..31378)
/gene="FIG4"
/locus_tag="YNL325C"
/EC_number="3.1.3.-"
/note="Phosphatidylinositol 3,5-bisphosphate
(PtdIns[3,5]P) phosphatase; required for efficient mating
and response to osmotic shock; physically associates with
and regulated by Vac14p; contains a SAC1-like domain"
/codon_start=1
/product="phosphatidylinositol-3,5-bisphosphate
5-phosphatase"
/protein_id="NP_014074.1"
/db_xref="GI:6324005"
/db_xref="SGD:S000005269"
/db_xref="GeneID:855392"
/translation="MNNDAMEHTLGGGILTTSGSKQRKTSKFVMGKYTLYETKDRMYI
VGSNKRETMFRILEIDLTVPRGELTVLEDNVFFTRNEIMNVLASLEEATEDGLHKKIT
GYGLLGFIKFTCWYYLIMVTKYSQVAVIGGHGIYHIDGIDIIPITNNYKKPEKSSDEA
RLLNIFKDLDLTKTFYFSYTYDITNTLQTNILREKLKAVDRCDITIPCGITDYNEMFV
WNNNLLSPIFACIDTVFDWFQCIIHGFIDQVNVSVLGKSIYITLIARRSHHFAGARFL
KRGVNNKGHVANEVETEQIVTDMILTPFHQPGNGFFDSDRYTSFVQHRGSIPLYWTQD
ASNLTTKPPIRINVVDPFFSPAALHFDNLFQRYGGGTIQILNLIKTKEKTPRETKLLW
EFEQCIDYLNEFLPTLKKLDYTSWDMSRASKQDGQGVIEFLEKYAVNTVTTTGIFHNG
PDFASTKIQEGICRSNCIDCLDRTNAAQFVIGKRALGCQLKSLGIIDNSYLEYDSDIV
NILTELFHDLGDTIALQYGGSHLVNTMETYRKINQWSSHSRDMIESIKRFYSNSFVDA
QRQDAINLFLGHYSWREGFPSLWEMNTDFYLHNAYSLNMPKRSYIHWWNDYNIKSVKE
LINEELIATGNDVTREKIIKNVRGYPGAFDNYWNEYYLPRSVTWIRDLFAYNMNSTRR
YHNALSKQDKAMSPFTSRKQSWLNNKLKMITSSKSLEKAEGRVVETTDLDRDTSPKQE
LELYEHYLHIISDRSQKLEEKMNSFSYSKYPIFISHESSEIPPMRKVIGEPLVDIAED
FTDVYDDDDDGDDENDEMTTEALLIAPDHVSVDEKFYEKVLNVDDYKPALDDYSAVIH
IKPDNLQLYRDLCFSKDIQLDFQ"
STS 28836..29641
/standard_name="D1S3690"
/db_xref="UniSTS:474268"
gene 31944..33188
/gene="LEM3"
/locus_tag="YNL323W"
/gene_synonym="BRE3; ROS3"
/db_xref="GeneID:855393"
mRNA 31944..33188
/gene="LEM3"
/locus_tag="YNL323W"
/gene_synonym="BRE3; ROS3"
/product="Lem3p"
/transcript_id="NM_001183161.1"
/db_xref="GI:296147459"
/db_xref="GeneID:855393"
CDS 31944..33188
/gene="LEM3"
/locus_tag="YNL323W"
/gene_synonym="BRE3; ROS3"
/note="Membrane protein of the plasma membrane and ER,
interacts specifically in vivo with the phospholipid
translocase (flippase) Dnf1p; involved in translocation of
phospholipids and alkylphosphocholine drugs across the
plasma membrane"
/codon_start=1
/product="Lem3p"
/protein_id="NP_014076.1"
/db_xref="GI:6324006"
/db_xref="SGD:S000005267"
/db_xref="GeneID:855393"
/translation="MVNFDLGQVGEVFRRKDKGAIVSGDNPEEEEDVDASEFEEDEVK
PVRTKNRRPKEDAFTQQRLAAINPVLTPRTVLPLYLLIAVVFVIVGGCILAQNSKVDE
VTIYYQDCMTNATSSWSDIPSEHWQFVFHKYKTYNTAPQWRFVDDESDDFTKQRGTCQ
IRFTTPSDMKNNVYLNYVLEKFAANHRRYVLSFSEDQIRGEDASYETVHDATGINCKP
LSKNADGKIYYPCGLIANSMFNDTFPLQLTNVGDTSNNYSLTNKGINWESDKKRYKKT
KYNYTQIAPPPYWEKMYPDGYNETNIPDIQDWEEFQNWMRPGAFDKITKLIRINKNDT
LPAGEYQLDIGLHWPVLEFNGKKGIYLTHGSHLGGRNPFLGIVYLIGGCICAAMALIL
LTFWLFGGRKIADASSLSWNMK"
gene complement(33294..34235)
/gene="KRE1"
/locus_tag="YNL322C"
/db_xref="GeneID:855394"
mRNA complement(33294..34235)
/gene="KRE1"
/locus_tag="YNL322C"
/product="Kre1p"
/transcript_id="NM_001183160.1"
/db_xref="GI:296147460"
/db_xref="GeneID:855394"
CDS complement(33294..34235)
/gene="KRE1"
/locus_tag="YNL322C"
/note="Cell wall glycoprotein involved in beta-glucan
assembly; serves as a K1 killer toxin membrane receptor"
/codon_start=1
/product="Kre1p"
/protein_id="NP_014077.1"
/db_xref="GI:6324007"
/db_xref="SGD:S000005266"
/db_xref="GeneID:855394"
/translation="MMRRTLLHSFATLLLSLSLWSAAVMAAVTTQVTVVTNVAGALVT
ETTIWDPATAAAAATTTAQTGFFTTVFTTTNDVGTTVTLTQTVNRATMLPTTTTSTSS
TGKTTTTVPTATSSLSSGLYLSTVTTTNDLGTTVTLTQTFTHSSTSATSSASSSVSSS
VSSSGSSSSVKTTTSTGSAVAETGTRPDPSTDFTEPPVSAVTSLSIDSYITITEGTTS
TYTTTRAPTSMWVTVVRQGNTITVQTTFVQRFSSQYVTVASPSVGSIGMGTLTGTVGV
IKSAIKKTVSHNEAQHLGMSSFTSILGGLLTVLIWFL"
gene 34696..37422
/gene="VNX1"
/locus_tag="YNL321W"
/db_xref="GeneID:855395"
mRNA 34696..37422
/gene="VNX1"
/locus_tag="YNL321W"
/product="Vnx1p"
/transcript_id="NM_001183159.1"
/db_xref="GI:296147461"
/db_xref="GeneID:855395"
CDS 34696..37422
/gene="VNX1"
/locus_tag="YNL321W"
/note="Calcium/H+ antiporter localized to the endoplasmic
reticulum membrane; member of the calcium exchanger (CAX)
family; potential Cdc28p substrate"
/codon_start=1
/product="Vnx1p"
/protein_id="NP_014078.1"
/db_xref="GI:6324008"
/db_xref="SGD:S000005265"
/db_xref="GeneID:855395"
/translation="MAKNNHISASGNSTSGDHRLKEEVLTPTTSASTPHRIFSVDDDP
KEIQNDIRYLEGLHEGLKFALHANKSKRSVSSQSPIVHSSNNTLHHHEHQQHLPPTLE
SLSSKSHSVPDLNTATPSSPKRMHSSIRELPHDDNDDEDANDDSRFIIHDSHGHDLLI
DEINCQSPSHLENNDQASNASSTESFTLRERQDAINETHPFGIRIWKPALYKKHRSVQ
RTAAQDIHETQLKTITWEVTCSNVLWFILFGFPIAILFYSAAIVVFLLGGGGLVTNSA
KEYSKCLYKLANYFLWPFGKMVYLLQDEQYLQEDKDEGISMQQFYNWVTSYSNRLVFH
QSQAKFQQREDHPAPATESSSLMPPANTTATPLNSNHPSYNSIRHEIPHAAAQRRYFG
RGKWSWGRVLFYTIFHLVLQPILAVLSLCLWLLVFTIPMSNVLWQIMYHCRRHPLALG
FKYVENSSQSHENEITQQQLNKNILLCTFRAAGWHYYKYTVDGTNVIVVNLISIVFFT
IFDFYVLKNFLHWKTWFTYESSIFILCLTSTIPLAFYIGQAVASISAQTSMGVGAVIN
AFFSTIVEIFLYCVALQQKKGLLVEGSMIGSILGAVLLLPGLSMCGGALNRKTQRYNP
ASAGVSSALLIFSMIVMFVPTVLYEIYGGYSVNCADGANDRDCTFSHPPLKFNRLFTH
VIQPMSISCAIVLFCAYIIGLWFTLRTHAKMIWQLPIADPTSTAPEQQEQNSHDAPNW
SRSKSTCILLMSTLLYAIIAEILVSCVDAVLEDIPSLNPKFLGLTIFALIPNTTEFLN
AISFAIHGNVALSMEIGSAYALQVCLLQIPSLVIYSIFYTWNVKKSMINIRTQMFPLV
FPRWDIFGAMTSVFMFTYLYAEGKSNYFKGSMLILLYIIIVVGFYFQGALSE"
gene 37700..38554
/locus_tag="YNL320W"
/db_xref="GeneID:855396"
mRNA 37700..38554
/locus_tag="YNL320W"
/product="hypothetical protein"
/transcript_id="NM_001183158.1"
/db_xref="GI:296147462"
/db_xref="GeneID:855396"
CDS 37700..38554
/locus_tag="YNL320W"
/note="hypothetical protein; the authentic, non-tagged
protein is detected in highly purified mitochondria in
high-throughput studies"
/codon_start=1
/product="hypothetical protein"
/protein_id="NP_014079.1"
/db_xref="GI:6324009"
/db_xref="SGD:S000005264"
/db_xref="GeneID:855396"
/translation="MLWKVSKMFLGGLVALTTISVATLYHYQNRLVYPSWAQGARNHV
DTPDSRGIPYEKLTLITQDHIKLEAWDIKNENSTSTVLILCPNAGNIGYFILIIDIFY
RQFGMSVFIYSYRGYGNSEGSPSEKGLKLDADCVISHLSTDSFHSKRKLVLYGRSLGG
ANALYIASKFRDLCDGVILENTFLSIRKVIPYIFPLLKRFTLLCHEIWNSEGLMGSCS
SETPFLFLSGLKDEIVPPFHMRKLYETCPSSNKKIFEFPLGSHNDTIIQDGYWDIIRD
FLIEKGFI"
gene complement(38707..40329)
/gene="HXT14"
/locus_tag="YNL318C"
/db_xref="GeneID:855398"
mRNA complement(38707..40329)
/gene="HXT14"
/locus_tag="YNL318C"
/product="Hxt14p"
/transcript_id="NM_001183156.1"
/db_xref="GI:296147463"
/db_xref="GeneID:855398"
CDS complement(38707..40329)
/gene="HXT14"
/locus_tag="YNL318C"
/note="Protein with similarity to hexose transporter
family members, expression is induced in low glucose and
repressed in high glucose; the authentic, non-tagged
protein is detected in highly purified mitochondria in
high-throughput studies"
/codon_start=1
/product="Hxt14p"
/protein_id="NP_014081.1"
/db_xref="GI:6324011"
/db_xref="SGD:S000005262"
/db_xref="GeneID:855398"
/translation="MTAQIPYQHSSGYISHFHNNELDAGRGRDYNVTIKYLDDKEENI
EGQAAKISHNASLHIPVLLCLVISLGGFIFGWDIGTIGGMTNMVSFQEKFGTTNIIHD
DETIFVSTKKLTDLQIGLIISIFNISCGVGALTLSKIGDWIGRKGGIWFALVVYCIGI
TIQILSYGRWYFLTLGRAVTGIGVGVTTVLVPMFLSENSPLKIRGSMVSTYQLIVTFG
ILMGNILNFICERCYKDPTQNIAWQLPLFLGYIWAIIIGMSLVYVPESPQYLAKIKND
VPSAKYSFARMNGIPATDSMVIEFIDDLLENNYNNEETNNESKKQSLVKRNTFEFIMG
KPKLWLRLIIGMMIMAFQQLSGINYFFYYGTSVFKGVGIKDPYITSIILSSVNFLSTI
LGIYYVEKWGHKTCLLYGSTNLLFYMMTYATVGTFGRETDFSNIVLIIVTCCFIFWFA
ITLGPVTFVLVSELFPLRTRAISMAICTFINWMFNFLISLLTPMIVSKIDFKLGYIFA
ACLLALIIFSWILVPETRKKNEQEINKIFEPE"
gene 40619..42016
/gene="PFS2"
/locus_tag="YNL317W"
/db_xref="GeneID:855399"
mRNA 40619..42016
/gene="PFS2"
/locus_tag="YNL317W"
/product="Pfs2p"
/transcript_id="NM_001183155.1"
/db_xref="GI:296147464"
/db_xref="GeneID:855399"
CDS 40619..42016
/gene="PFS2"
/locus_tag="YNL317W"
/note="Integral subunit of the pre-mRNA cleavage and
polyadenylation factor (CPF) complex; plays an essential
role in mRNA 3'-end formation by bridging different
processing factors and thereby promoting the assembly of
the processing complex"
/codon_start=1
/product="Pfs2p"
/protein_id="NP_014082.1"
/db_xref="GI:6324012"
/db_xref="SGD:S000005261"
/db_xref="GeneID:855399"
/translation="MDGHNQNQYQNQNQIQQSQQPPLKKYVTQRRSVDVSSPYINLYY
NRRHGLPNLVVEPETSYTIDIMPPNAYRGRDRVINLPSKFTHLSSNKVKHVIPAIQWT
PEGRRLVVATYSGEFSLWNASSFTFETLMQAHDSAVTTMKYSHDSDWMISGDADGMIK
IWQPNFSMVKEIDAAHTESIRDMAFSSNDSKFVTCSDDNILKIWNFSNGKQERVLSGH
HWDVKSCDWHPEMGLIASASKDNLVKLWDPRSGNCISSILKFKHTVLKTRFQPTKGNL
LMAISKDKSCRVFDIRYSMKELMCVRDETDYMTLEWHPINESMFTLACYDGSLKHFDL
LQNLNEPILTIPYAHDKCITSLSYNPVGHIFATAAKDRTIRFWTRARPIDPNAYDDPT
YNNKKINGWFFGINNDINAVREKSEFGAAPPPPATLEPHALPNMNGFINKKPRQEIPG
IDSNIKSSTLPGLSI"
gene complement(42071..43075)
/gene="PHA2"
/locus_tag="YNL316C"
/db_xref="GeneID:855400"
mRNA complement(42071..43075)
/gene="PHA2"
/locus_tag="YNL316C"
/product="prephenate dehydratase PHA2"
/transcript_id="NM_001183154.1"
/db_xref="GI:296147465"
/db_xref="GeneID:855400"
CDS complement(42071..43075)
/gene="PHA2"
/locus_tag="YNL316C"
/EC_number="4.2.1.51"
/note="Prephenate dehydratase, catalyzes the conversion of
prephanate to phenylpyruvate, which is a step in the
phenylalanine biosynthesis pathway"
/codon_start=1
/product="prephenate dehydratase PHA2"
/protein_id="NP_014083.2"
/db_xref="GI:37362685"
/db_xref="SGD:S000005260"
/db_xref="GeneID:855400"
/translation="MASKTLRVLFLGPKGTYSHQAALQQFQSTSDVEYLPAASIPQCF
NQLENDTSIDYSVVPLENSTNGQVVFSYDLLRDRMIKKALSLPAPADTNRITPDIEVI
AEQYVPITHCLISPIQLPNGIASLGNFEEVIIHSHPQVWGQVECYLRSMAEKFPQVTF
IRLDCSSTSESVNQCIRSSTADCDNILHLAIASETAAQLHKAYIIEHSINDKLGNTTR
FLVLKRRENAGDNEVEDTGLLRVNLLTFTTRQDDPGSLVDVLNILKIHSLNMCSINSR
PFHLDEHDRNWRYLFFIEYYTEKNTPKNKEKFYEDISDKSKQWCLWGTFPRNERYYHK
"
gene complement(43324..44280)
/gene="ATP11"
/locus_tag="YNL315C"
/db_xref="GeneID:855401"
mRNA complement(43324..44280)
/gene="ATP11"
/locus_tag="YNL315C"
/product="Atp11p"
/transcript_id="NM_001183153.1"
/db_xref="GI:296147466"
/db_xref="GeneID:855401"
CDS complement(43324..44280)
/gene="ATP11"
/locus_tag="YNL315C"
/note="Molecular chaperone, required for the assembly of
alpha and beta subunits into the F1 sector of
mitochondrial F1F0 ATP synthase"
/codon_start=1
/product="Atp11p"
/protein_id="NP_014084.1"
/db_xref="GI:6324014"
/db_xref="SGD:S000005259"
/db_xref="GeneID:855401"
/translation="MWRLTRKIGTRIHISNQLSPIFNKAIGTVPVFRFYSSSPEQKYR
KKLLEEAQKQGFNSIEELKNHLKETIESKKREFNKIDPLKELEDYQQKTQMENNNSKH
LMTKSRSPLDPSAPKVPFKTLDSFLDVGKLKDLSKQEVEFLWRARWAQKDNTLCAVIP
VSVYDKMMANARNNPIFVLPLPRQVQSEDAKPNEEQGMELHYIQWQFVGPQTTHCMMT
SLAEYKLHQEFARPHTTLQFHSDLVKDKGIVFMNGHVEPDTNVNVQDAQLLLLNVQRF
YGAMGEETPVAKQRVQLLRDFSKASPGFTVEKLISLSQSMEN"
gene 44447..45214
/gene="DAL82"
/locus_tag="YNL314W"
/db_xref="GeneID:855402"
mRNA 44447..45214
/gene="DAL82"
/locus_tag="YNL314W"
/product="Dal82p"
/transcript_id="NM_001183152.1"
/db_xref="GI:296147467"
/db_xref="GeneID:855402"
CDS 44447..45214
/gene="DAL82"
/locus_tag="YNL314W"
/note="Positive regulator of allophanate inducible genes;
binds a dodecanucleotide sequence upstream of all genes
that are induced by allophanate; contains an UISALL
DNA-binding, a transcriptional activation, and a
coiled-coil domain"
/codon_start=1
/product="Dal82p"
/protein_id="NP_014085.1"
/db_xref="GI:6324015"
/db_xref="SGD:S000005258"
/db_xref="GeneID:855402"
/translation="MDESVDPVELLLRLLIRHKPHLKPYAYRQDSWQRVLDEYNRQTG
SRYRQSRTLKTKFRRLKDLFSADRAQFSPSQLKLMGALLDEAPEHPRPRTKFGNESSS
SLSSSSFIKSHPGPDPFQQLSSAEHPNNHSSDDEHSGSQPLPLDSITIGIPPTLHTIP
MILSKDNDVGKVIKSPKINKGTNRFSETVLPPQMAAEQSWSDSNMELEICLDYLHNEL
EVIKKRQEDFECKVLNKLNIIEALLSQMRPPSQGDKI"
gene complement(45308..48022)
/gene="EMW1"
/locus_tag="YNL313C"
/db_xref="GeneID:855403"
mRNA complement(45308..48022)
/gene="EMW1"
/locus_tag="YNL313C"
/product="Emw1p"
/transcript_id="NM_001183151.1"
/db_xref="GI:296147468"
/db_xref="GeneID:855403"
CDS complement(45308..48022)
/gene="EMW1"
/locus_tag="YNL313C"
/note="Essential conserved protein with a role in cell
wall integrity; contains six TPR (tetratricopeptide
repeat) domains clustered in the C-terminal region;
conditional mutant is suppressed by overexpression of
GFA1; protein abundance increases in response to DNA
replication stress"
/codon_start=1
/product="Emw1p"
/protein_id="NP_014086.1"
/db_xref="GI:6324016"
/db_xref="SGD:S000005257"
/db_xref="GeneID:855403"
/translation="METLLHAKLLLSAEVESLKSGSFDQTYVKKAEHIISGESYQLVQ
QFVDKFKGKISISGEISTSSVIAALNDFLNVEVFKMGQENEMLFLAIALLQTFIQNNY
TGPAARLKAISGLFGKTGIEIGAVNTALSRSLAIMGQPAYEFMDDPLYLVLSLLLLER
ITGQKSLFDVTPDQEIPLPIISAESTPGLLAVAYWWWARALLTQLSLIPEPSGFQASV
ASAIYQSADLAYAITKELPESIHEDFKRELCAMYYLENVKCSLAINTEHLCLPSLTRA
KKITNFEFVMTGARATRTKYQQKAHAGLIILAKSFTFQNFALRTTSATPETFALESDL
LLEKPHFESIADEPLDEQIYSKRQKVDLNEGYEEDKLLPLALRQENIPKLLLDLNPND
QPTLSDYDNIQLLLRLYTIKNTTPAKDPLVEEELTALLSRILYQNGDKNWSIFARSLW
ERSIIETTKAKTIERGLLQMQSLVEELDLKIKSKLVPSSSEINVASRLSYIHQLPFIP
RWQLDATLAEKYMSLGILKSAVEIYERLGMACETALCYAAVGDEKKAEEILLQRINEN
DSDARAYSILGDIKQDPSLWEKSWEIGKYVNAKNSLAKYYFNPPPKSGAQPNYSATLK
HLNDSLRQYPLSFETWYFYGCVGLQCGKMQIAAEAFTRCVSLDPYHALSWSNLSAAYT
KMDKLKEAYSCLKRAISCDAQKNWKIWENYMLVAVKLNEWEDVLTACKQLVSIRRDKS
GEGSIDLPIIEKLVELLVTSEYPEEPQQLSYFQKSCTEFICNTLPQVITTSARCWRLV
ARVELWRKRPWAALECHEKAYRAISHNPDLEVEEKVWNDTVDACEDLVAAYESLGEME
GKYGPGSLVCKDWKYKCRSTIKALMSKGKGRWDDSPGWDRLVEARSQI"
gene 48287..49216
/gene="RFA2"
/locus_tag="YNL312W"
/gene_synonym="BUF1; RPA2"
/db_xref="GeneID:855404"
mRNA join(48287..48293,48402..49216)
/gene="RFA2"
/locus_tag="YNL312W"
/gene_synonym="BUF1; RPA2"
/product="Rfa2p"
/transcript_id="NM_001183150.1"
/db_xref="GI:296147469"
/db_xref="GeneID:855404"
CDS join(48287..48293,48402..49216)
/gene="RFA2"
/locus_tag="YNL312W"
/gene_synonym="BUF1; RPA2"
/note="Subunit of heterotrimeric Replication Protein A
(RPA); RPA is a highly conserved single-stranded DNA
binding protein involved in DNA replication, repair, and
recombination; protein abundance increases in response to
DNA replication stress"
/codon_start=1
/product="Rfa2p"
/protein_id="NP_014087.1"
/db_xref="GI:6324017"
/db_xref="SGD:S000005256"
/db_xref="GeneID:855404"
/translation="MATYQPYNEYSSVTGGGFENSESRPGSGESETNTRVNTLTPVTI
KQILESKQDIQDGPFVSHNQELHHVCFVGVVRNITDHTANIFLTIEDGTGQIEVRKWS
EDANDLAAGNDDSSGKGYGSQVAQQFEIGGYVKVFGALKEFGGKKNIQYAVIKPIDSF
NEVLTHHLEVIKCHSIASGMMKQPLESASNNNGQSLFVKDDNDTSSGSSPLQRILEFC
KKQCEGKDANSFAVPIPLISQSLNLDETTVRNCCTTLTDQGFIYPTFDDNNFFAL"
gene complement(49397..51688)
/gene="SKP2"
/locus_tag="YNL311C"
/db_xref="GeneID:855405"
mRNA complement(49397..51688)
/gene="SKP2"
/locus_tag="YNL311C"
/product="putative SCF ubiquitin ligase complex subunit
SKP2"
/transcript_id="NM_001183149.1"
/db_xref="GI:296147470"
/db_xref="GeneID:855405"
CDS complement(49397..51688)
/gene="SKP2"
/locus_tag="YNL311C"
/note="F-box hypothetical protein predicted to be part of
an SCF ubiquitin protease complex; involved in regulating
protein levels of sulfur metabolism enzymes; may interact
with ribosomes, based on co-purification experiments"
/codon_start=1
/product="putative SCF ubiquitin ligase complex subunit
SKP2"
/protein_id="NP_014088.1"
/db_xref="GI:6324018"
/db_xref="SGD:S000005255"
/db_xref="GeneID:855405"
/translation="MKRLQLFGRSKYFSLVSSAAKEEEEEEEGCADAKSLLHSTSHDI
KSRSLRFNDKSSLMCLPTKVLLLILRTLDFNTLVTLCQVNSRFYNLITNEFLFQNVIL
DSKLSLLKFNALIHSEFHTSNIVTHSGDCSTQSRSQNARFLVRSIEFKNPQSQDSLLK
YSKFYNKSGQDSIIAGSYKLDSYDKDVKKLNNIRLNDETPIITSERIKLLDKLESNYF
HYTYIELMLDIIDYLPNLTRVILSDVEPNFKIPLWYSVFNDGSRDFFKKIIKGQQSIT
NEDLRTFQLSKKFVKEYESKYYSLPRLKILEIKANNKRQRTFNRQRHHQKLVLRPSLF
CCFGIINELKLENVTIDTESLDTPMEFLPLFLKNEDNELYSLQSPITALTLDSCDVVP
GNGILRLFHSYFKMVKHLSLLKINSKFDLLLCSCFPSLSNLTIDCNSKCFTNEQVVGE
SYYFQQRSLDTEDDFDDCNSMTETLFEAPSDSKIITPPPTSSVVLSLNLNYISRTTGN
DVSNNPSPDNNKKPAMLTAAQLQNFQRQRIPEFHSFYHYYRLLWERLPSKNISINVIN
IPFTNVYPLSPLSFWEHLARTITSVDETDEDVGDENDQETLIGYENNSIRDNIPNANA
VPNLSTVMSPESDIHHTYYWNNSVRRCLRDSLIKLKNRTIEYRDLDVEEFLQNVTLEN
FFNDFQDPENFKDIPNINLWCFLRNLSKFKAVKIRMLRHFSLCTPRTRYDWELLLKPV
LRVNVPIEVRDKDGFVLYSYGQK"
gene complement(51907..52431)
/gene="ZIM17"
/locus_tag="YNL310C"
/gene_synonym="HEP1; TIM15"
/db_xref="GeneID:855406"
mRNA complement(51907..52431)
/gene="ZIM17"
/locus_tag="YNL310C"
/gene_synonym="HEP1; TIM15"
/product="Zim17p"
/transcript_id="NM_001183148.1"
/db_xref="GI:296147471"
/db_xref="GeneID:855406"
CDS complement(51907..52431)
/gene="ZIM17"
/locus_tag="YNL310C"
/gene_synonym="HEP1; TIM15"
/note="Heat shock protein with a zinc finger motif;
essential for protein import into mitochondria; may act
with Pam18p to facilitate recognition and folding of
imported proteins by Ssc1p (mtHSP70) in the mitochondrial
matrix"
/codon_start=1
/product="Zim17p"
/protein_id="NP_014089.2"
/db_xref="GI:99030930"
/db_xref="SGD:S000005254"
/db_xref="GeneID:855406"
/translation="MIPRTRTLLQSKIPITRYFARCWAPRVRYNVCRTLPAAALHTNI
IAHNEVKKDDKKVHLGSFKVDKPKMMIAFTCKKCNTRSSHTMSKQAYEKGTVLISCPH
CKVRHLIADHLKIFHDHHVTVEQLMKANGEQVSQDVGDLEFEDIPDSLKDVLGKYAKN
NSENASQLPHPSQK"
gene 52662..53924
/gene="STB1"
/locus_tag="YNL309W"
/db_xref="GeneID:855407"
mRNA 52662..53924
/gene="STB1"
/locus_tag="YNL309W"
/product="Stb1p"
/transcript_id="NM_001183147.1"
/db_xref="GI:296147472"
/db_xref="GeneID:855407"
CDS 52662..53924
/gene="STB1"
/locus_tag="YNL309W"
/note="Protein with a role in regulation of MBF-specific
transcription at Start, phosphorylated by Cln-Cdc28p
kinases in vitro; unphosphorylated form binds Swi6p and
binding is required for Stb1p function; expression is
cell-cycle regulated"
/codon_start=1
/product="Stb1p"
/protein_id="NP_014090.2"
/db_xref="GI:37362686"
/db_xref="SGD:S000005253"
/db_xref="GeneID:855407"
/translation="MSQPQMSPEKEQELASKILHRAELAQMTRQLKLGLSNVPSTKRK
QDSTTKKRSGEDAEDVDEDHKTLLEAISPAKKPLHDDTNKMTVISPVKFVEKPNTPPS
SRQRKAEDRSQQIKPRKEDTPSTPRASATPIILPHASSHYQRPHDKNFMTPKRNNNNS
SNHSNNNNNIKKKAAGSKDAPQDSDNTAGADLLMYLATSPYNKSSHHGTPMAVRMPTT
PRSYHYASQLSLNGNTASTSNDAVRFSHIKPSASSPQSTFKSNLLPNFPDESLMDSPS
LYLSNNNGSVQATLSPQQRRKPTTNTLHPPSNVPTTPSRELNGTNFNLLRTPNFNMGD
YLHNLFSPSPRVPAQQGASNTSASIPSVPAMVPGSSSNTSAIATAAISSHTTNNFLDM
NANGIPLIVGPGTDRIGEGESIDDKLTD"
gene complement(54122..55897)
/gene="KRI1"
/locus_tag="YNL308C"
/db_xref="GeneID:855408"
mRNA complement(54122..55897)
/gene="KRI1"
/locus_tag="YNL308C"
/product="Kri1p"
/transcript_id="NM_001183146.1"
/db_xref="GI:296147473"
/db_xref="GeneID:855408"
CDS complement(54122..55897)
/gene="KRI1"
/locus_tag="YNL308C"
/note="Essential nucleolar protein required for 40S
ribosome biogenesis; associate with snR30; physically and
functionally interacts with Krr1p"
/codon_start=1
/product="Kri1p"
/protein_id="NP_014091.1"
/db_xref="GI:6324021"
/db_xref="SGD:S000005252"
/db_xref="GeneID:855408"
/translation="MPRKKSAAKRAREQAKKEAAVPATDTATIKTSETSATTVKPAIE
ASKSYVPSEDEEEDEEEEEEEDDYGELITDEVENGINQVLDAIKNNKTDKLLDPKVKF
FEDPESAAAKLANREGKHKPIYLKDYHRMNILSGDALKEDDEEYEHATVDGKQSFVSQ
QREEKTQLLNEIKSAFSDEENEESSGDEDDGFLKKKEPSTKKEGKNLPDPTVNEENFL
EEFVNQQAWIPKKGDKVISLDLNNNEEDDEEFEDAAEKFENAYNFRYEDPNAAEIISY
ARSQATLRRSDDSSRRRKREEKRKIKEQIKAEKETALQKKKTKKLNKLTDILEQLTKE
YGAEINADMVKKITDTLLKNDFKEEEWDNVVAELFNEEFYQQEGKPTWNEDDEIMGDF
YADADGDDQTEEGEVEKEQKEEDEEEGPKRKKSKKEEKLQKKKEKRKVNELVENALEQ
NKLALIEEVEKEEEERKSRSRTKEEQDLKFRYREVSPESFGLTAREIFAADDTDLNEF
IGLKKFAPYRSKELRAKDKRKVMKARRLREWRKKTFKNENGLAPVEAEAGEKDEDTIL
IPVEKASKSKHKRGHSHKHKGHQKK"
gene complement(56446..57573)
/gene="MCK1"
/locus_tag="YNL307C"
/gene_synonym="CMS1; YPK1"
/db_xref="GeneID:855409"
mRNA complement(56446..57573)
/gene="MCK1"
/locus_tag="YNL307C"
/gene_synonym="CMS1; YPK1"
/product="Mck1p"
/transcript_id="NM_001183145.1"
/db_xref="GI:296147474"
/db_xref="GeneID:855409"
CDS complement(56446..57573)
/gene="MCK1"
/locus_tag="YNL307C"
/gene_synonym="CMS1; YPK1"
/EC_number="2.7.12.1"
/note="Protein serine/threonine/tyrosine
(dual-specificity) kinase; involved in control of
chromosome segregation and in regulating entry into
meiosis; interacts with Clb2p and Mih1p; inhibits
Clb2p-Cdk1 activity; related to mammalian glycogen
synthase kinases of the GSK-3 family"
/codon_start=1
/product="Mck1p"
/protein_id="NP_014092.1"
/db_xref="GI:6324022"
/db_xref="SGD:S000005251"
/db_xref="GeneID:855409"
/translation="MSTEEQNGVPLQRGSEFIADDVTSNKSNNTRRMLVKEYRKIGRG
AFGTVVQAYLTQDKKNWLGPFAIKKVPAHTEYKSRELQILRIADHPNIVKLQYFFTHL
SPQDNKVYQHLAMECLPETLQIEINRYVTNKLEMPLKHIRLYTYQIARGMLYLHGLGV
CHRDIKPSNVLVDPETGVLKICDFGSAKKLEHNQPSISYICSRFYRAPELIIGCTQYT
TQIDIWGLGCVMGEMLIGKAIFQGQEPLLQLREIAKLLGPPDKRFIFFSNPAYDGPLF
SKPLFSGSSQQRFEKYFGHSGPDGIDLLMKILVYEPQQRLSPRRILAHQFFNELRNDD
TFLPRGFTEPIKLPNLFDFNDFELQILGEFADKIKPTKVAE"
gene 58155..58808
/gene="MRPS18"
/locus_tag="YNL306W"
/db_xref="GeneID:855410"
mRNA 58155..58808
/gene="MRPS18"
/locus_tag="YNL306W"
/product="mitochondrial 37S ribosomal protein YmS18"
/transcript_id="NM_001183144.1"
/db_xref="GI:296147475"
/db_xref="GeneID:855410"
CDS 58155..58808
/gene="MRPS18"
/locus_tag="YNL306W"
/note="Mitochondrial ribosomal protein of the small
subunit; essential for viability, unlike most other
mitoribosomal proteins"
/codon_start=1
/product="mitochondrial 37S ribosomal protein YmS18"
/protein_id="NP_014093.1"
/db_xref="GI:6324023"
/db_xref="SGD:S000005250"
/db_xref="GeneID:855410"
/translation="MLLQPVWKGCRWTQFVRPIRRWNSTGTNRGVPFSFKDISNQEDI
TNISYPSSSDSVLTKSNGSSEVYKPKEEVVKYILHGKFTKNNTHLTFSSVVEDKNFHK
NKGLTYNDTMLYYLNLPQKVKISLSTGCLGFRKAARGEYEAAFQTSGRMFELIKEKNM
LNKDIEVVMDDFGKGRAAFISALVGKEGASVVKKVVKISDATKLKFGGVRSPKMRRL"
gene complement(58898..59791)
/gene="BXI1"
/locus_tag="YNL305C"
/gene_synonym="YBH3"
/db_xref="GeneID:855411"
mRNA complement(58898..59791)
/gene="BXI1"
/locus_tag="YNL305C"
/gene_synonym="YBH3"
/product="Bxi1p"
/transcript_id="NM_001183143.1"
/db_xref="GI:296147476"
/db_xref="GeneID:855411"
CDS complement(58898..59791)
/gene="BXI1"
/locus_tag="YNL305C"
/gene_synonym="YBH3"
/note="Protein involved in apoptosis; variously described
as containing a BCL-2 homology (BH3) domain or as a member
of the BAX inhibitor family; reported to promote apoptosis
under some conditions and to inhibit it in others;
localizes to ER and vacuole; may link the unfolded protein
response to apoptosis via regulation of calcium-mediated
signaling; translocates to mitochondria under
apoptosis-inducing conditions in a process involving Mir1p
and Cor1p"
/codon_start=1
/product="Bxi1p"
/protein_id="NP_014094.1"
/db_xref="GI:6324024"
/db_xref="SGD:S000005249"
/db_xref="GeneID:855411"
/translation="MSGPPPPYEEQSSHLYGQPASSQDGNAFIPEDFKYSTVVISCEP
IIRQRFMHKVYSLLSCQLLASLSFCYWASVSTSLQNFIMSHIALFYICMVVSLVSCIW
LAVSPRPEDYEASVPEPLLTGSSEEPAQEQRRLPWYVLSSYKQKLTLLSIFTLSEAYC
LSLVTLAYDKDTVLSALLITTIVVVGVSLTALSERFENVLNSATSIYYWLNWGLWIMI
GMGLTALLFGWNTHSSKFNLLYGWLGAILFTAYLFIDTQLIFRKVYPDEEVRCAMMLY
LDIVNLFLSILRILANSNDDN"
gene 60297..61550
/gene="YPT11"
/locus_tag="YNL304W"
/db_xref="GeneID:855412"
mRNA 60297..61550
/gene="YPT11"
/locus_tag="YNL304W"
/product="Ypt11p"
/transcript_id="NM_001183142.1"
/db_xref="GI:296147477"
/db_xref="GeneID:855412"
CDS 60297..61550
/gene="YPT11"
/locus_tag="YNL304W"
/note="Rab family GTPase that interacts with the
C-terminal tail domain of Myo2p; mediates distribution of
mitochondria and endoplasmic reticuli to daughter cells"
/codon_start=1
/product="Ypt11p"
/protein_id="NP_014095.2"
/db_xref="GI:82795261"
/db_xref="SGD:S000005248"
/db_xref="GeneID:855412"
/translation="MSQRKRYSLNVVTSPSIPSPTPSAPIRTNESNWEAASPASAASS
FLPNVHHGGTVLNPGLGIMRSPSLNKSGAFGRSGSSGSSTVIEPSNIKLLLIGDANVG
KTAMILSYCRELLTRAEMSRSARLRHQQQQQHKDLGLKKTVVNHRLSMKEKRKRYSSN
DFEKEFKDINHFADETSDFGNPNIGDDNNHEMADPNEIVIETRSTIGIDIKTNLVNID
NRFFNVILWDTAGQERYQNAIIPSLYKKTNAVILTYDITNAKSFQSCMERWIVQALEN
FSSQDLLKARFFLVGNKIDLYKERQVTHYDVVQMVQEMQLKHGIKISGNFEVSCKWVN
VVERTMNMIILDLVENGCFENNDPCVSITTSDDVQGHEQEFHDTVEEPFNFTRQRQHQ
LEKNNTVDITKPNDDIANNQSICCV"
rep_origin 61599..61895
/note="ARS1406;
Autonomously Replicating Sequence"
/db_xref="SGD:S000118383"
gene complement(61958..62943)
/gene="RPS19B"
/locus_tag="YNL302C"
/gene_synonym="RP55B"
/db_xref="GeneID:855414"
mRNA complement(join(61958..62372,62924..62943))
/gene="RPS19B"
/locus_tag="YNL302C"
/gene_synonym="RP55B"
/product="ribosomal 40S subunit protein S19B"
/transcript_id="NM_001183140.1"
/db_xref="GI:296147478"
/db_xref="GeneID:855414"
CDS complement(join(61958..62372,62924..62943))
/gene="RPS19B"
/locus_tag="YNL302C"
/gene_synonym="RP55B"
/note="Protein component of the small (40S) ribosomal
subunit, required for assembly and maturation of pre-40 S
particles; homologous to mammalian ribosomal protein S19,
no bacterial homolog; mutations in human RPS19 are
associated with Diamond Blackfan anemia; RPS19B has a
paralog, RPS19A, that arose from the whole genome
duplication"
/codon_start=1
/product="ribosomal 40S subunit protein S19B"
/protein_id="NP_014097.1"
/db_xref="GI:6324027"
/db_xref="SGD:S000005246"
/db_xref="GeneID:855414"
/translation="MAGVSVRDVAAQDFINAYASFLQRQGKLEVPGYVDIVKTSSGNE
MPPQDAEGWFYKRAASVARHIYMRKQVGVGKLNKLYGGAKSRGVRPYKHIDASGSINR
KVLQALEKIGIVEISPKGGRRISENGQRDLDRIAAQTLEEDE"
gene complement(63570..64562)
/gene="RPL18B"
/locus_tag="YNL301C"
/gene_synonym="RP28B"
/db_xref="GeneID:855415"
mRNA complement(join(63570..64018,64451..64562))
/gene="RPL18B"
/locus_tag="YNL301C"
/gene_synonym="RP28B"
/product="ribosomal 60S subunit protein L18B"
/transcript_id="NM_001183139.1"
/db_xref="GI:296147479"
/db_xref="GeneID:855415"
CDS complement(join(63570..64018,64451..64562))
/gene="RPL18B"
/locus_tag="YNL301C"
/gene_synonym="RP28B"
/note="Ribosomal 60S subunit protein L18B; homologous to
mammalian ribosomal protein L18, no bacterial homolog;
RPL18B has a paralog, RPL18A, that arose from the whole
genome duplication"
/codon_start=1
/product="ribosomal 60S subunit protein L18B"
/protein_id="NP_014098.1"
/db_xref="GI:6324028"
/db_xref="SGD:S000005245"
/db_xref="GeneID:855415"
/translation="MGIDHTSKQHKRSGHRTAPKSDNVYLKLLVKLYTFLARRTDAPF
NKVVLKALFLSKINRPPVSVSRIARALKQEGAANKTVVVVGTVTDDARIFEFPKTTVA
ALRFTAGARAKIVKAGGECITLDQLAVRAPKGQNTLILRGPRNSREAVRHFGMGPHKG
KAPRILSTGRKFERARGRRRSKGFKV"
gene 65744..66052
/gene="TOS6"
/locus_tag="YNL300W"
/db_xref="GeneID:855416"
mRNA 65744..66052
/gene="TOS6"
/locus_tag="YNL300W"
/product="Tos6p"
/transcript_id="NM_001183138.1"
/db_xref="GI:296147480"
/db_xref="GeneID:855416"
CDS 65744..66052
/gene="TOS6"
/locus_tag="YNL300W"
/note="Glycosylphosphatidylinositol-dependent cell wall
protein, expression is periodic and decreases in respone
to ergosterol perturbation or upon entry into stationary
phase; depletion increases resistance to lactic acid"
/codon_start=1
/product="Tos6p"
/protein_id="NP_014099.1"
/db_xref="GI:6324029"
/db_xref="SGD:S000005244"
/db_xref="GeneID:855416"
/translation="MKFSTLSTVAAIAAFASADSTSDGVTYVDVTTTPQSTTSMVSTV
KTTSTPYTTSTIATLSTKSISSQANTTTHEISTYVGAAVKGSVAGMGAIMGAAAFALL
"
gene 66517..68445
/gene="TRF5"
/locus_tag="YNL299W"
/db_xref="GeneID:855417"
mRNA 66517..68445
/gene="TRF5"
/locus_tag="YNL299W"
/product="non-canonical poly(A) polymerase TRF5"
/transcript_id="NM_001183137.1"
/db_xref="GI:296147481"
/db_xref="GeneID:855417"
CDS 66517..68445
/gene="TRF5"
/locus_tag="YNL299W"
/EC_number="2.7.7.-"
/note="Non-canonical poly(A) polymerase, involved in
nuclear RNA degradation as a component of the TRAMP
complex; catalyzes polyadenylation of hypomodified tRNAs,
and snoRNA and rRNA precursors; overlapping but
non-redundant functions with Pap2p"
/codon_start=1
/product="non-canonical poly(A) polymerase TRF5"
/protein_id="NP_014100.2"
/db_xref="GI:81360384"
/db_xref="SGD:S000005243"
/db_xref="GeneID:855417"
/translation="MTRLKAKYSPTKGKRKEDKHTKRMRKSSFTRTQKMLEVFNDNRS
HFNKYESLAIDVEDDDTFGNLVLMENDKSDVDIPVIEEVTSSEDEQRAESSKRNNSLE
DNQDFIAFSDSSEDETEQIKEDDDERSSFLLTDEHEVSKLTSQQSLNTESACNVEYPW
IRNHCHSKQRRIADWLTSEIKDFVHYISPSKNEIKCRNRTIDKLRRAVKELWSDADLH
VFGSFATDLYLPGSDIDCVVNSRNRDKEDRNYIYELARHLKNKGLAIRMEVIVKTRVP
IIKFIEPQSQLHIDVSFERTNGLEAAKLIREWLRDSPGLRELVLIIKQFLHSRRLNNV
HTGGLGGFTVICLVYSFLNMHPRIKSNDIDVLDNLGVLLIDFFELYGKNFGYDDVAIS
ISDGYASYIPKSCWRTLEPSRSKFSLAIQDPGDPNNNISRGSFNMKDIKKAFAGAFEL
LVNKCWELNSATFKDRVGKSILGNVIKYRGQKRDFNDERDLVQNKAIIENERYHKRRT
RIVQEDLFINDTEDLPVEEIYKLDEPAKKKQKAKKDKREGEIKKSAIPSPPPDFGVSR
SKLKRKVKKTDQGSLLHQNNLSIDDLMGLSENDQESDQDQKGRDTPSGQDEKSPLETK
TVDAQTRRDYWLSKGQAL"
gene 68915..71443
/gene="CLA4"
/locus_tag="YNL298W"
/gene_synonym="ERC10"
/db_xref="GeneID:855418"
mRNA 68915..71443
/gene="CLA4"
/locus_tag="YNL298W"
/gene_synonym="ERC10"
/product="Cla4p"
/transcript_id="NM_001183136.1"
/db_xref="GI:296147482"
/db_xref="GeneID:855418"
CDS 68915..71443
/gene="CLA4"
/locus_tag="YNL298W"
/gene_synonym="ERC10"
/EC_number="2.7.11.1"
/note="Cdc42p-activated signal transducing kinase of the
PAK (p21-activated kinase) family, along with Ste20p and
Skm1p; involved in septin ring assembly, vacuole
inheritance, cytokinesis, sterol uptake regulation;
phosphorylates Cdc3p and Cdc10p"
/codon_start=1
/product="Cla4p"
/protein_id="NP_014101.1"
/db_xref="GI:6324031"
/db_xref="SGD:S000005242"
/db_xref="GeneID:855418"
/translation="MSLSAAANKISDNDFQNIGPAPRPPSSNSQGRTCYNQTQPITKL
MSQLDLTSASHLGTSTSKKKSGWVSYKDDGILSFIWQKRYLMLHDSYVALYKNDKQND
DAILKIPLTSIISVSRTQLKQYCFELVRCSDRNSVSSGSSSSLNVSSDSNSKKSIYIA
TKTESDLHSWLDAIFAKCPLLSGVSSPTNFTHKVHVGFDPETGSFVGMPTNWEKLLKH
SRITGEDWNNNSAAVIQVLQFYQEYNGAGNPTNTLDKPQSGETSSSQKSLPNSYNDNK
LRNNSVNSKSSSGVSSSMVSQRKTSQPPNTKSPVSLGSGSLPPINTKLPTSQSNIPRH
LQNVPNQQYPKMRNGHSPTNGQFPRGPMHPNNSQRSLQQQQQQQQQQKQQHQQYPYHH
QGPSPSPSPSPSPLNPYRPHHNMINPYSKQPQSPLSSQSTQNQAIPRYAQNSSPTAAH
FQPQRTAPKPPISAPRAPYPSNQNATSNTHVQPVAPKNDQSTPQTMRQAPKRPDADVA
QPGGVAKPKKPARPTMSTAEIMSKLKKVTVNADPSQCFKVIEKAGQGASGSVYLAERT
HIPTESNMIELINNDIDEPHVGDKVAIKQMVLSKQPRKELIVNEILVMKDSRHKNIVN
FLEAYLRTDDDLWVVMEFMEGGSLTDIIENSPTNDNSHSPLTEPQIAYIVRETCQGLK
FLHDKHIIHRDIKSDNVLLDTRARVKITDFGFCARLTDKRSKRATMVGTPYWMAPEVV
KQREYDEKIDVWSLGIMTIEMLEGEPPYLNEDPLKALYLIATNGTPKLKHPESLSLEI
KRFLSVCLCVDVRYRASTEELLHHGFFNMACDPKDLTSLLEWKE"
gene complement(71673..76583)
/gene="MON2"
/locus_tag="YNL297C"
/gene_synonym="YSL2"
/db_xref="GeneID:855420"
mRNA complement(71673..76583)
/gene="MON2"
/locus_tag="YNL297C"
/gene_synonym="YSL2"
/product="Mon2p"
/transcript_id="NM_001183135.1"
/db_xref="GI:296147483"
/db_xref="GeneID:855420"
CDS complement(71673..76583)
/gene="MON2"
/locus_tag="YNL297C"
/gene_synonym="YSL2"
/note="Peripheral membrane protein with a role in
endocytosis and vacuole integrity, interacts with Arl1p
and localizes to the endosome; member of the Sec7p family
of proteins"
/codon_start=1
/product="Mon2p"
/protein_id="NP_014102.1"
/db_xref="GI:6324033"
/db_xref="SGD:S000005241"
/db_xref="GeneID:855420"
/translation="MAMNTGGFDSMQRQLEAELRSLSSESKRRNSTIRHASDKSIEIL
KRVHSFEELERHPDFALPFVLACQSRNAKMTTLAMQCLQGLSTVPSIPRSRLSEILDA
FIEATHLAMEIQLKVLQVVPIFFKTYGKFIYGPLCKKLLLCCSNLLHVPNKAPVVVGT
ASATLQQLIDEIFDRLSIESVVDDKQYEVLISNSESIKVNVYRYDANKLFDNICSLNE
ISSNGAVSDEEMLLDIGDIPIDYGLEILESILKNSQKNLLECQDLQYLLRVKAIPLLL
RCISSSRHFSTAVRSCRCLKLLIRKEYLSILELELEVILSLLIHGISVESNLSGWQRV
LSLELFKDLSQDPEIVNTLYMDYDNYPDKKHVFKYLLKECIVLLNSPEYITFLAPSKV
VEKMDSPLITTENSTVKTKFMHLLDKSNAPSINITYIISLILTICNHLCEGLNKSALE
SSPLEKKIEDKEREEGTGNDSTVVKVYSGLFSGLFELNKLFLYSTSLETSIFHLVVRA
FQKLAHSAGVLSLKDKLRACMKLFSILITNNVTSSNQYSFNDTSKSAKNQHTRNISTS
SVTTSPVESTKNPSRSIADSAQNKEMKRRLHPRNISSRQVSLLRALISLSISLGPIFD
SESWRYTFLTWQWITYYIYGPSADFKESFYSEDIPPPPILTKSDVTSIESSLTKFFES
TSSYSCSTFHLVLTRLILDSKNTLTLEQTNLNLNNDIGYHPLDAKDEIIPCIYNKAFF
VNKIGELATYNCKKFLFGKNGKELWSLISTYMIKLISNREMDNDSLRLYTVRVFTDII
KKATNEVGNSDEQDNKVKQFGTLENLVIDSLMATINSIKQLDIGKQEIYNGTINVESD
ILFQLLLTLKEILNEFGELLMNSWTNIFNIINSPFEWTVEDTDFSVNEDIDDSSLFEG
IVQKHKNMIQVSYDVFKLISDDFLQSLPMSVIKFVIDTLVNFVSQKRNLNISFSSISQ
FWLVGDYLRVRFNPETLNLSDEKRRSLSEKINNQKLIEIITSSSSHDWELYNGLWIYL
LKNLINCTNDDRVEVKNGAVQTFFRIIDSHSVCFPPWDLIFLEVIEPLLTKEWSTEEL
ENETDFINVTLQGLIKLYPEHFKDFKNNTTCAKEWSMLLDFLKRLLSSTSNNTKNAVI
LNYQTLLKEIITIEDVPSDILKKCCEIFTDYNITYSDLSTNASSKTEYDCIYELITGF
PPLYQLISKYDAMTDEFVEKVLLLFNSAIKYPLLPEFVQDKTKPSSMQKAILSGLDIF
MTNDSKDTEILILLQLSTISILAFDTREKITKKLGPKLPKASLNRLPTFEAISYMSCS
NLRNRIAKIDQFGISTLKAKHILRILKNLAEIIKRKSLITGSESDEIPIWVLASNCFC
DLSNKIFKSLQEDAENPLKDNFCDLFINVIVVTLQRINPELDNLTEIDDLNEYSKYRE
ILLENRIIDLFNERQLDTFIYAVWDCSFLYEFDELENALMQDCGTFSELSQKLSSFDF
SCIFGSTTNPRFQTKYKCSLECLQDLVNFMLNTNEKLRKLTAPYLSARIALALRRYIS
DEYLIGRAPIPKLRKTELATLLNGLCVILRGVLDQNSTLGNKQIGVENLQTLSPLILR
TIPVSHKMDGLQDKVLELSLGFTKLD"
gene 76946..78520
/locus_tag="YNL295W"
/db_xref="GeneID:855421"
mRNA 76946..78520
/locus_tag="YNL295W"
/product="hypothetical protein"
/transcript_id="NM_001183133.1"
/db_xref="GI:296147484"
/db_xref="GeneID:855421"
CDS 76946..78520
/locus_tag="YNL295W"
/codon_start=1
/product="hypothetical protein"
/protein_id="NP_014104.1"
/db_xref="GI:6324034"
/db_xref="SGD:S000005239"
/db_xref="GeneID:855421"
/translation="MEHQALRRLVLYCPNFIRRGALRQNMTRVSCRHMSGKGGGRDEK
GDCNEEKDSSKDLGRVPSKMKRAYDGETVIKEGDSHAESLAQQGKQPTDLAYNSRSKI
SGSNLHLLVPRVASTDYISNKEVHTEGLFAGYRPLFLGNSGFPSDARKGKNFHELDDV
LPNIQVVDASEKDGKLNVQEIIEDLQRTSLRESIHSMEQLPSSHKRKPVIPWDASISG
MVYNDMPFKYVPKNIILKMKPFKLLRIERKSQAKNARKPTMIKLQFHNRRINDTPELV
NLYHNKSRLHESLYNTKPLQESGYSSANTSKRQKMLKARSDFEHKQKNYAYKHTFIKN
DQELFRNELTKLNKILAREFKKLTKLSIHNEFKREHLPLAVYVSKSKGTKKLFRRSLK
MKIMDHIYPVYTTILSTLTNSRDSKKFENKIKAYIEKIIVRLSDEVPSTYFFQDGVDC
IIQPSPIHNFKRMHWLRYTKRHNTFWGRTIHKDVQVSFNDKYVVTRSGVRYTRYPTNL
NTQLLETAFEEWDYYE"
gene complement(78659..80260)
/gene="RIM21"
/locus_tag="YNL294C"
/gene_synonym="PAL2"
/db_xref="GeneID:855422"
mRNA complement(78659..80260)
/gene="RIM21"
/locus_tag="YNL294C"
/gene_synonym="PAL2"
/product="Rim21p"
/transcript_id="NM_001183132.1"
/db_xref="GI:296147485"
/db_xref="GeneID:855422"
CDS complement(78659..80260)
/gene="RIM21"
/locus_tag="YNL294C"
/gene_synonym="PAL2"
/note="pH sensor molecule, component of the RIM101
pathway; has a role in cell wall construction and alkaline
pH response; is glycosylated and phosphorylated; interacts
with Dfg16p and Rim9p to form a pH-sensing complex;
localization to the plasma membrane is dependent on Dfg16p
and Rim9p; has similarity to A. nidulans PalH"
/codon_start=1
/product="Rim21p"
/protein_id="NP_014105.1"
/db_xref="GI:6324035"
/db_xref="SGD:S000005238"
/db_xref="GeneID:855422"
/translation="MNLWRHSPEELAAYNSCHPMKLGSGVLIQLPLYDNSAVYAEDIT
FRSFCCERVPVYVSTVLRNSSPYRYLDEVINDWQKFIQVSDYVGGSAEYAIYAVILSI
TSNFVITVFLTVICCINISGRAYKRILQLLRIASLLASLNLTIFITKVLRRLEKEHNV
YGVVRAHSIMHIFSDDMTFVVLDFLATLMFQFCQVGIVIRLFQRAQEKRIIFFIGVIL
TITANILWVIPPFANHTTKHRNDWQILRPFVYLFRIAIATSYASIVIYHIWQKKKLWF
KFNQMGLLTLLTILVVLLLPGFFLADVSNLWISELGEVFNTTCYVTSTVITWEWLDRL
NVLERKEEAQSILGRPIFEEEQQDYRFAKYALRVQNALTRRESQDASTDRHDTSSNSE
VCDLQTISRYDPEDQISVGRSIDRMHFNDRGTYKDVALKKLGYARDKILYFTDQIVQK
SVGHNNSSSSKNEKTKQRKAMVRKRLGLDKPGIYIYSTKDVVFNSDEDDDENAEDEDD
DEYEVGSEGNNNSSATFTSDHIGHI"
gene 80640..82541
/gene="MSB3"
/locus_tag="YNL293W"
/gene_synonym="GYP3"
/db_xref="GeneID:855423"
mRNA 80640..82541
/gene="MSB3"
/locus_tag="YNL293W"
/gene_synonym="GYP3"
/product="Msb3p"
/transcript_id="NM_001183131.1"
/db_xref="GI:296147486"
/db_xref="GeneID:855423"
CDS 80640..82541
/gene="MSB3"
/locus_tag="YNL293W"
/gene_synonym="GYP3"
/note="Rab GTPase-activating protein; regulates
endocytosis via activation of Vps21p and Ypt7p; also acts
on Ypt52p and Sec4p; also required for proper actin
organization; localizes to the plasma membrane and sites
of polarized growth, and a portion localizes to endosomes
and vacuoles; similar to Msb4p; relocalizes from bud neck
to cytoplasm upon DNA replication stress"
/codon_start=1
/product="Msb3p"
/protein_id="NP_014106.1"
/db_xref="GI:6324036"
/db_xref="SGD:S000005237"
/db_xref="GeneID:855423"
/translation="MQNDQQRFSLQNRTVLAHPYKRLGGAFTVKSPSVPNFHDKMHSD
HSSSDSALVNGSFRANDHRSVEPSCLGQASPSEHDGNLSVIDLYGDEVESQRAEGEDD
DDNNGDNGNEDLEEVHSDDLDLVPDDDNRQRVELEGAASATSANSNGINNTHFDRYGF
KKQNNYISEAEYDKWWVEYSQYCVRRKHKWQLLLEKSGLPVTDDSPSRFPSKSERLKR
YVRKGIPAEWRGNAWWHFARGQEKLNKNKGVYSQLLRKMKQIKKQNPNEKQVQDLDII
ERDLNRTFPDNIHFQSSLHNKEGPPIIKSLRRVLVAFSLYNPKIGYCQSMNFLAGLLL
LFLDEERAFWMLVIITSRYLPGVHNINLEGVNIDQGVLMLCVKEYIPEVWSYIKPSID
HHQKNNKTFSPSNKKVLFNMQKNEFLYRLPPITLCTASWFMSCFVGVVPIETTLRIWD
CLFYEESHFLFKVSLAVLKLSEHDLSKIKPRNNSLNYSWGSNLNQRGGSMGQEDSDME
IFQVIQTFPKTLLNPNEIFEKIIFKRRFNLNRLDQDEIDRCRKFVAAQRLKFKTYGEL
LGNSTSEADLPINDNTDNKGIHITSDAVNEALSSEVYGFKKSLAGVHWNNSIKEKVKQ
MRKKKDKGD"
gene 82806..84017
/gene="PUS4"
/locus_tag="YNL292W"
/db_xref="GeneID:855424"
mRNA 82806..84017
/gene="PUS4"
/locus_tag="YNL292W"
/product="pseudouridine synthase PUS4"
/transcript_id="NM_001183130.1"
/db_xref="GI:296147487"
/db_xref="GeneID:855424"
CDS 82806..84017
/gene="PUS4"
/locus_tag="YNL292W"
/EC_number="4.2.1.70"
/note="Pseudouridine synthase, catalyzes only the
formation of pseudouridine-55 (Psi55), a highly conserved
tRNA modification, in mitochondrial and cytoplasmic tRNAs;
PUS4 overexpression leads to translational derepression of
GCN4 (Gcd- phenotype)"
/codon_start=1
/product="pseudouridine synthase PUS4"
/protein_id="NP_014107.1"
/db_xref="GI:6324037"
/db_xref="SGD:S000005236"
/db_xref="GeneID:855424"
/translation="MNGIFAIEKPSGITSNQFMLKLQHALTKSQVFSKEIQRATAERK
QQYEKQTGKKASKRKLRKVSKVKMGHGGTLDPLASGVLVIGIGAGTKKLANYLSGTVK
VYESEALFGVSTTSGDVEGEILSQNSVKHLNFDDLKTVEEKFVGQLKQTPPIYAALKM
DGKPLHEYAREGKPLPRAIEPRQVTIYDLKVFSDSLKRDHDYPLLRPTTEEAVDTVKN
LNANMLNDVLYFSKEYTEKHGLDSEVAKVEEPFPLSEQEEQEIQKEGDSYRAPKLHFK
ANVSSGTYIRSLVSDIGKSMRSSCYMVKLIRLQQQDWSLEKNNVFQLTDFTERDEKVW
SKVLEKVLDEGATVDVIEELKKAEKEIPADVKECIVSSDQPGDEATAETIETANAEEH
SNTLKRKIEQV"
gene complement(84169..85815)
/gene="MID1"
/locus_tag="YNL291C"
/db_xref="GeneID:855425"
mRNA complement(84169..85815)
/gene="MID1"
/locus_tag="YNL291C"
/product="Mid1p"
/transcript_id="NM_001183129.1"
/db_xref="GI:296147488"
/db_xref="GeneID:855425"
CDS complement(84169..85815)
/gene="MID1"
/locus_tag="YNL291C"
/note="N-glycosylated integral membrane protein of the ER
membrane and plasma membrane, functions as a
stretch-activated Ca2+-permeable cation channel required
for Ca2+ influx stimulated by pheromone; interacts with
Cch1p; forms an oligomer"
/codon_start=1
/product="Mid1p"
/protein_id="NP_014108.1"
/db_xref="GI:6324038"
/db_xref="SGD:S000005235"
/db_xref="GeneID:855425"
/translation="MIVWQALFVVYCLFTTSIHGLFQDFNPFANKNISLKFPSLNRWE
KNVMATGQQTIINSDSIYEWTPILSNITAGKKDSFVFTIDAEASGYGFAPTYEVLMFI
SGNICQMPMNRSDVDLTIYYSFNETVLENPNIGQSAVFQDGYIQALAISPVQSSSSNA
TSTYSNLYVVAELVNSTTEQPLSSSDASENWEYRLSISENDLVFQWDVRPWVEVLDTD
MNSALLSTGNVTADAKVYHNYSIYDPSLYDLYVYSYEDSVQLNQNYNLSLCAVKNGPY
LVSSQNTSNATVTSNSTNPLERTDLAIQKKITEYGGSVTEMFYVTGLNASTTYVAYLT
KKISNGDGLSSVGGILFSHVYFTTRSTDVCSLIFGLDFCSDVAYSVPTSSFSVGNKTL
MAQTYDHIAEALYANFSKALQLISCDADKDARYSPVMTCDDCAEAYRDWVCAVSIPRC
TTTSSQYYIHRDKSHNRNDYLNKFIKPLDDYYEILPCIDMCYTLVRNCPSDFQFSCPN
DLTTEDLLYQSYNFYMDTDYSTCNYIGNSSLMVIHPLDDT"
gene 86218..87240
/gene="RFC3"
/locus_tag="YNL290W"
/db_xref="GeneID:855426"
mRNA 86218..87240
/gene="RFC3"
/locus_tag="YNL290W"
/product="replication factor C subunit 3"
/transcript_id="NM_001183128.1"
/db_xref="GI:296147489"
/db_xref="GeneID:855426"
CDS 86218..87240
/gene="RFC3"
/locus_tag="YNL290W"
/note="Subunit of heteropentameric Replication factor C
(RF-C), which is a DNA binding protein and ATPase that
acts as a clamp loader of the proliferating cell nuclear
antigen (PCNA) processivity factor for DNA polymerases
delta and epsilon"
/codon_start=1
/product="replication factor C subunit 3"
/protein_id="NP_014109.1"
/db_xref="GI:6324039"
/db_xref="SGD:S000005234"
/db_xref="GeneID:855426"
/translation="MSTSTEKRSKENLPWVEKYRPETLDEVYGQNEVITTVRKFVDEG
KLPHLLFYGPPGTGKTSTIVALAREIYGKNYSNMVLELNASDDRGIDVVRNQIKDFAS
TRQIFSKGFKLIILDEADAMTNAAQNALRRVIERYTKNTRFCVLANYAHKLTPALLSR
CTRFRFQPLPQEAIERRIANVLVHEKLKLSPNAEKALIELSNGDMRRVLNVLQSCKAT
LDNPDEDEISDDVIYECCGAPRPSDLKAVLKSILEDDWGTAHYTLNKVRSAKGLALID
LIEGIVKILEDYELQNEETRVHLLTKLADIEYSISKGGNDQIQGSAVIGAIKASFENE
TVKANV"
gene 87897..88736
/gene="PCL1"
/locus_tag="YNL289W"
/gene_synonym="HCS26"
/db_xref="GeneID:855427"
mRNA 87897..88736
/gene="PCL1"
/locus_tag="YNL289W"
/gene_synonym="HCS26"
/product="Pcl1p"
/transcript_id="NM_001183127.1"
/db_xref="GI:296147490"
/db_xref="GeneID:855427"
CDS 87897..88736
/gene="PCL1"
/locus_tag="YNL289W"
/gene_synonym="HCS26"
/note="Cyclin, interacts with cyclin-dependent kinase
Pho85p; member of the Pcl1,2-like subfamily, involved in
the regulation of polarized growth and morphogenesis and
progression through the cell cycle; localizes to sites of
polarized cell growth"
/codon_start=1
/product="Pcl1p"
/protein_id="NP_014110.1"
/db_xref="GI:6324040"
/db_xref="SGD:S000005233"
/db_xref="GeneID:855427"
/translation="MCEYSKALHILLKSPVTDDIIKFLTDTTLRVVPSSNYPTPPGSP
GEKHLTRLPSLMTFITRLVRYTNVYTPTLLTAACYLNKLKRILPRDATGLPSTIHRIF
LACLILSAKFHNDSSPLNKHWARYTDGLFTLEDINLMERQLLQLLNWDLRVNTEDLIL
DLQPLLEPIKQDLARSSDQRKRINMMMSMNRRTCAGTSPIRSNNRFKLYEKQRNVSIA
SDLSSATLVDSCNDLRRLKDVTNIANNTVANTNYVRTVEKWNDNVNRQSWDLEQIMSQ
HGF"
gene 89210..89306
/locus_tag="snR40"
/db_xref="GeneID:9164969"
ncRNA 89210..89306
/locus_tag="snR40"
/ncRNA_class="snoRNA"
/product="SNR40"
/note="C/D box small nucleolar RNA (snoRNA), guides
2'-O-methylation of large subunit (LSU) rRNA at position
U898 and small subunit (SSU) rRNA at position G1271"
/db_xref="SGD:S000007304"
/db_xref="GeneID:9164969"
rep_origin 89531..89804
/note="ARS1407;
Autonomously Replicating Sequence"
/db_xref="SGD:S000118384"
gene 90303..91424
/gene="CAF40"
/locus_tag="YNL288W"
/db_xref="GeneID:855428"
mRNA 90303..91424
/gene="CAF40"
/locus_tag="YNL288W"
/product="CCR4-NOT core subunit CAF40"
/transcript_id="NM_001183126.1"
/db_xref="GI:296147491"
/db_xref="GeneID:855428"
CDS 90303..91424
/gene="CAF40"
/locus_tag="YNL288W"
/note="Evolutionarily conserved subunit of the CCR4-NOT
complex involved in controlling mRNA initiation,
elongation and degradation; binds Cdc39p"
/codon_start=1
/product="CCR4-NOT core subunit CAF40"
/protein_id="NP_014111.1"
/db_xref="GI:6324041"
/db_xref="SGD:S000005232"
/db_xref="GeneID:855428"
/translation="MFSAQKPIYGNGAGVNMGGGGPSTNNPGSMSMPGVPTSMGPGMN
QQIPSGGPMLMGNTPNNNNSNENGENNGNNGNNGGNDANATRNNPNMVNNRGAVHALD
DPNVYHWICQLTYGPQKEQALLELGRKREQFDDLAVVLWSSFGVMTSLLNEIISVYPM
LQPQMLSNNLSNRVCNALVLLQCVASHPETKHLFLQAHIPLFLFPFLNTTSRQRTFEY
LRLTSLGVIGALVKNDSQDVITFLLRTDIVPLCLRIMESSSELSKTVAIFILQKILLD
DVGLQYICATLERFYAVTNVLKDMVEHLTVSTPPGRLLKHIIRCYLRLSDDLEARRLL
KIVLPAKLRDNTFTEVLRDDVGSKRCLAQLLLTLNEETS"
gene 91994..94801
/gene="SEC21"
/locus_tag="YNL287W"
/db_xref="GeneID:855429"
mRNA 91994..94801
/gene="SEC21"
/locus_tag="YNL287W"
/product="Sec21p"
/transcript_id="NM_001183125.1"
/db_xref="GI:296147492"
/db_xref="GeneID:855429"
CDS 91994..94801
/gene="SEC21"
/locus_tag="YNL287W"
/note="Gamma subunit of coatomer, a heptameric protein
complex that together with Arf1p forms the COPI coat;
involved in ER to Golgi transport of selective cargo"
/codon_start=1
/product="Sec21p"
/protein_id="NP_014112.1"
/db_xref="GI:6324042"
/db_xref="SGD:S000005231"
/db_xref="GeneID:855429"
/translation="MSAHTYKKFENSTSGDLPDKMTIYQDCMNTFNESPVNSKRCRLL
ISRLLRLLAQGETFPQNEATALFFSISKLFQHQNDPLRQAVYLAIKELSGISEDVLMA
TSSIMKDVQNGSDLIKPDAIRSLTYVLDESTAFSAERLLKSAVVSRHPSISSAALCTS
YHLLPISEVTIRRFTNETQEAVLDLKQFPNQHGNSEYYPNSTYISQYHALGLLYQLKK
TDKMALLKLVRHFSENNSMKNQLAKVELVKIVNDLIYRDPQLFSQFRPLLSDWLSNKF
ESVQLETAKLITSFATRNSRLVAPELYAAAISALQSLLTVPRVSSRFAALRILNRISM
VSPEKIVVCNPELESLINDSNRNISTYAITTLLKTGTSKNISSLISTITNFIHDVSDD
FKIIIIDAVRTLSLNFPQEWKSILNFLIDVLKNSEGGFKFKNSIVEALIDIVSFVPQS
KELALENLCDFIEDCEFNEILVRILHLLGKEGPSAPNPSLYVRHIYNRVVLENSIIRS
AAVVALSKFALTKNDPTLYESIISLLKRIANDKDDEVRDRATIALEFIDSARNKDDVI
AQNLIESKYFYDIPSLESKLSSYISSNTDSFATAFDVNQVRKFTEDEMKAINLKRKQE
QIFNQKSETTLDTTPEAESVPEKRADANSFAGPNLDDHQEDLLATKYADELLSIEQIK
PFGQLVNSSRAISLTEPEAEFVVRGVKHLFKDNVVLQFNITNTLTDIALDNVSVVCTP
EISDEAELEELFTLQVDRLLPSEEAACYVAFKKLDEIVMEGFLNNLTFTTKEINPDTN
EPFDGDEGFQDEYEIDSIFLNAGDYVKSSFTGNFSATFDELPCEEVAVFNIQEDLSIQ
EVVDKIILNSSCLPVESTQFAPSDSNSHTLKLFGKSALTGSKVALQIKMIKSSKGLAL
KVHGKGEDSLLCSDLVNGLMQ"
gene 95223..96080
/gene="CUS2"
/locus_tag="YNL286W"
/db_xref="GeneID:855430"
mRNA 95223..96080
/gene="CUS2"
/locus_tag="YNL286W"
/product="Cus2p"
/transcript_id="NM_001183124.1"
/db_xref="GI:296147493"
/db_xref="GeneID:855430"
CDS 95223..96080
/gene="CUS2"
/locus_tag="YNL286W"
/note="Protein that binds to U2 snRNA and Prp11p, may be
involved in U2 snRNA folding; contains two RNA recognition
motifs (RRMs)"
/codon_start=1
/product="Cus2p"
/protein_id="NP_014113.1"
/db_xref="GI:6324043"
/db_xref="SGD:S000005230"
/db_xref="GeneID:855430"
/translation="MDADELELKGHLKKLKKEELLRRKQLKESNLQKRELEYNNASKN
TSIYISGLPTDKTTKEGLTEQFCKYGMIRTNRDGEPLCKLYVNDKGAFKGDALITYSK
EESVTLAIEMMNESIFLGKQIRVERAQFQNKEGDNMHGKENDLKEFNGPEPPIKRLKK
AKSEGEGEVIDYNDDESLAKADRTVIFANVFNIYKSYTNDDINDIQEDLLEGCEEIGQ
VDSISVSPNKGEATVVFKNNKVALQCCKIMTGRYFDGQKLLAFISGDENTSSTSDKNE
DSEVEDDLI"
gene complement(96241..96312)
/gene="SUF6"
/locus_tag="tG(UCC)N"
/db_xref="GeneID:855432"
tRNA complement(96241..96312)
/gene="SUF6"
/locus_tag="tG(UCC)N"
/product="tRNA-Gly"
/note="Glycine tRNA (tRNA-Gly), predicted by tRNAscan-SE
analysis; can mutate to suppress +1 frameshift mutations
in glycine codons"
/db_xref="SGD:S000006591"
/db_xref="GeneID:855432"
rep_origin 96247..96463
/note="ARS1409;
Putative replication origin, identified in multiple array
studies, not yet confirmed by plasmid-based assay"
/db_xref="SGD:S000130140"
LTR 96451..96609
/note="Ty4 LTR"
/db_xref="SGD:S000007140"
mobile_element complement(96610..102523)
/note="YNLCTy1-1; Ty1 element, LTR retrotransposon of the
Copia (Pseudoviridae) group; contains co-transcribed genes
TYA Gag and TYB Pol, encoding proteins involved in
structure and function of virus-like particles, flanked by
two direct repeats"
/mobile_element_type="retrotransposon:YNLCTy1-1"
/db_xref="SGD:S000007134"
LTR complement(96610..96941)
/note="Ty1 LTR"
/db_xref="SGD:S000007129"
gene complement(96964..102232)
/locus_tag="YNL284C-B"
/db_xref="GeneID:855433"
mRNA complement(join(<96964..100926,100928..>102232))
/locus_tag="YNL284C-B"
/transcript_id="NM_001184415.1"
/db_xref="GI:296147494"
/db_xref="GeneID:855433"
CDS complement(join(96964..100926,100928..102232))
/locus_tag="YNL284C-B"
/EC_number="2.7.7.49"
/EC_number="3.4.23.-"
/EC_number="3.1.26.4"
/EC_number="2.7.7.7"
/ribosomal_slippage
/note="Retrotransposon TYA Gag and TYB Pol genes;
transcribed/translated as one unit; polyprotein is
processed to make a nucleocapsid-like protein (Gag),
reverse transcriptase (RT), protease (PR), and integrase
(IN); similar to retroviral genes"
/codon_start=1
/product="gag-pol fusion protein"
/protein_id="NP_058178.1"
/db_xref="GI:7839194"
/db_xref="SGD:S000007387"
/db_xref="GeneID:855433"
/translation="MESQQLSQHSPISHGSACASVTSKEVHTNQDPLDVSASKIQEYD
KASTKANSQQTTTPASSAVPENPHHASPQTAQSHSPQNGPYQQQCMMTQNQANPSGWS
FYGRPSMIPYTPYQMSPMYFPPGPHSQFPQYPSSVGTPLSTPSPESGNTFTDSSSADS
DMTSTKKYVRPPPMLTSPNDFLNWVKTYIKFLQNSNLGDIIPTATRKAVRQMTDDELT
FLCHTFQLFAPSQFLPTWVKDILSADYTDIMKILSKSINKMQSDTQEVNDITTLATLH
YNGSTPADAFEAEVTNILDRLNNNGIPINNKVACQFIMRGLSGEYKFLRYARHRYIHM
TVADLFSDIHSMYEEQQESKRNKSTYRRNPSDEKKDSRTYTNTTKPKSITRNSQKPNN
SQSRTARAHNVSTSNNSSGPDNDLIRGSTTEPIQLKNKHDLHLGQELTESTVNHTNHS
DDELPGHLLLDSGASRTLIRSAHHIHSASSNPGINVVDAQKRNIPINAIGDLQFHFQD
NTKTSIKVLHTPNIAYDLLSLNELAAVDITACFTKNVLERSDGTVLAPIVKYGDFYWV
SKKYLLPSNISVPTINNVHTSESTRKYPYPFIHRMLAHANAQTIRYSLKNNTITYFNE
SDVDWSSAIDYQCPDCLIGKSTKHRHIKGSRLKYQNSYEPFQYLHTDIFGPVHNLPKS
APSYFISFTDETTKFRWVYPLHDRREDSILDVFTTILAFIKNQFQASVLVIQMDRGSE
YTNRTLHKFLEKNGITPCYTTTADSRAHGVAERLNRTLLDDCRTQLQCSGLPNHLWFS
AIEFSTIVRNSLASPKSKKSARQHAGLAGLDISTLLPFGQPVIVNDHNPNSKIHPRGI
PGYALHPSRNSYGYIIYLPSLKKTVDTTNYVILQGKESRLDQFNYDALTFDEDLNRLT
ASYQSFIASNEIQQSDDLNIESDHDFQSDIELHPEQPRNVLSKAVSPTDSTPPSTHTE
DSKRVSKTNIRAPREVDPNISKSNILPSKKRSSTPQISDIESTGSGGMHRLDVPLLAP
MSQYNTHESSHTSKSKDFRHSDSYSDNETNHTNVPISSTGGTNNKTVPQTSEQETEKR
IIHRSPSIDTSSSESNSLHHVVPIKTSDTCPKENTEESIIADLPLPDLPPEPPTKLSD
SFKELPPINSRQTNSSLGGIGDSNAYTTINSKKRSLEDNETEIKVSRDTWNTKNMRSL
EPPRSKKRIHLIAAVKAVKSIKPIRTTLRYDEAITYNKDIKEKEKYIEAYHKEVNQLL
KMKTWDTDRYYDRKEIDPKRVINSMFIFNRKRDGTHKARFVARGDIQHPDTYDSGMQS
NTVHHYALMTSLSLALDNNYYITQLDISSAYLYADIKEELYIRPPPHLGMNDKLIRLK
KSLYGLKQSGANWYETIKSYLIQQCGMEEVRGWSCVFKNSQVTICLFVDDMVLFSKNL
NSNKRIIEKLKMQYDTKIINLGESDEEIQYDILGLEIKYQRGKYMKLGMENSLTEKIP
KLNVPLNPKGRKLSAPGQPGLYIDQQELELEEDDYKMKVHEMQKLIGLASYVGYKFRF
DLLYYINTLAQHILFPSKQVLDMTYELIQFIWNTRDKQLIWHKSKPVKPTNKLVVISD
ASYGNQPYYKSQIGNIYLLNGKVIGGKSTKASLTCTSTTEAEIHAISESVPLLNNLSY
LIQELDKKPITKGLLTDSKSTISIIISNNEEKFRNRFFGTKAMRLRDEVSGNHLHVCY
IETKKNIADVMTKPLPIKTFKLLTNKWIH"
gene complement(100910..102232)
/locus_tag="YNL284C-A"
/db_xref="GeneID:855434"
mRNA complement(<100910..>102232)
/locus_tag="YNL284C-A"
/transcript_id="NM_001184414.1"
/db_xref="GI:296147495"
/db_xref="GeneID:855434"
CDS complement(100910..102232)
/locus_tag="YNL284C-A"
/note="Retrotransposon TYA Gag gene co-transcribed with
TYB Pol; translated as TYA or TYA-TYB polyprotein; Gag is
a nucleocapsid protein that is the structural constituent
of virus-like particles (VLPs); similar to retroviral Gag"
/codon_start=1
/product="gag protein"
/protein_id="NP_058179.1"
/db_xref="GI:7839193"
/db_xref="SGD:S000007386"
/db_xref="GeneID:855434"
/translation="MESQQLSQHSPISHGSACASVTSKEVHTNQDPLDVSASKIQEYD
KASTKANSQQTTTPASSAVPENPHHASPQTAQSHSPQNGPYQQQCMMTQNQANPSGWS
FYGRPSMIPYTPYQMSPMYFPPGPHSQFPQYPSSVGTPLSTPSPESGNTFTDSSSADS
DMTSTKKYVRPPPMLTSPNDFLNWVKTYIKFLQNSNLGDIIPTATRKAVRQMTDDELT
FLCHTFQLFAPSQFLPTWVKDILSADYTDIMKILSKSINKMQSDTQEVNDITTLATLH
YNGSTPADAFEAEVTNILDRLNNNGIPINNKVACQFIMRGLSGEYKFLRYARHRYIHM
TVADLFSDIHSMYEEQQESKRNKSTYRRNPSDEKKDSRTYTNTTKPKSITRNSQKPNN
SQSRTARAHNVSTSNNSSGPDNDLIRGSTTEPIQLKNKHDLHLRPGTY"
LTR complement(102192..102523)
/note="Ty1 LTR"
/db_xref="SGD:S000007130"
LTR complement(102632..102700)
/note="Ty3 LTR"
/db_xref="SGD:S000007133"
gene 102716..102789
/locus_tag="tN(GUU)N1"
/db_xref="GeneID:855435"
tRNA 102716..102789
/locus_tag="tN(GUU)N1"
/product="tRNA-Asn"
/note="Asparagine tRNA (tRNA-Asn), predicted by
tRNAscan-SE analysis"
/db_xref="SGD:S000006673"
/db_xref="GeneID:855435"
gene complement(103134..104102)
/gene="MRPL10"
/locus_tag="YNL284C"
/gene_synonym="MRPL18"
/db_xref="GeneID:855436"
mRNA complement(103134..104102)
/gene="MRPL10"
/locus_tag="YNL284C"
/gene_synonym="MRPL18"
/product="mitochondrial 54S ribosomal protein YmL10/YmL18"
/transcript_id="NM_001183122.1"
/db_xref="GI:296147496"
/db_xref="GeneID:855436"
CDS complement(103134..104102)
/gene="MRPL10"
/locus_tag="YNL284C"
/gene_synonym="MRPL18"
/note="Mitochondrial ribosomal protein of the large
subunit; appears as two protein spots (YmL10 and YmL18) on
two-dimensional SDS gels"
/codon_start=1
/product="mitochondrial 54S ribosomal protein YmL10/YmL18"
/protein_id="NP_014115.1"
/db_xref="GI:6324045"
/db_xref="SGD:S000005228"
/db_xref="GeneID:855436"
/translation="MKAERQTGLRNSFTTVIGRKLINTFVPSMMLTSVAGNDIFFRGL
FKSPVLAFQSYRYVSILGQLKPSDGSTKSFKRLGRGPSSGLGKTSGRGQKGQKARGKV
KSWFEGGQTPIYKLFPKIGFTNVGAKPLKELNLKRIQWFHDKNRLHLQPGEVLDMNKM
RKLGLVTGPIKYGVKILASGKFHYNLPIALEASRASAKAIAAIEKAGGKFTARYYTPL
GLRAHLNPQWFLEKRGRVPLQARPTKRRDIDFYSKEEKRGYLVMEKDKLLQDIKEAQN
KGSRHFLKQNVKKSSLEIELEELSPEKDWVPVVSNSKVMNIKALDH"
gene 104805..104877
/locus_tag="tT(AGU)N1"
/db_xref="GeneID:855437"
tRNA 104805..104877
/locus_tag="tT(AGU)N1"
/product="tRNA-Thr"
/note="Threonine tRNA (tRNA-Thr), predicted by tRNAscan-SE
analysis"
/db_xref="SGD:S000006744"
/db_xref="GeneID:855437"
gene complement(105184..106695)
/gene="WSC2"
/locus_tag="YNL283C"
/gene_synonym="STA3"
/db_xref="GeneID:855438"
mRNA complement(105184..106695)
/gene="WSC2"
/locus_tag="YNL283C"
/gene_synonym="STA3"
/product="Wsc2p"
/transcript_id="NM_001183121.1"
/db_xref="GI:296147497"
/db_xref="GeneID:855438"
CDS complement(105184..106695)
/gene="WSC2"
/locus_tag="YNL283C"
/gene_synonym="STA3"
/note="Partially redundant sensor-transducer of the
stress-activated PKC1-MPK1 signaling pathway involved in
maintenance of cell wall integrity and recovery from heat
shock; secretory pathway Wsc2p is required for the arrest
of secretion response"
/codon_start=1
/product="Wsc2p"
/protein_id="NP_014116.1"
/db_xref="GI:6324046"
/db_xref="SGD:S000005227"
/db_xref="GeneID:855438"
/translation="MHLDLIHKSFILVWLIYIRAALADQFTYKACYSASDIRKLGLTY
KGVYEYQSVSYCQNECPGQAVVALFNGTGCYCGGSVAQLQSLTQVDSSKCDVSCAGWP
YQNCGGSSAMNVYINNAASTADSTSSTATSTSTTSSSSTSVSSKTSTKLDTKTSTSSS
ATHSSSSSSTTSTTTSSSETTTSSSSSSSSSSTSTTSTTSTTSSTTSTSSSPSTTSSS
TSASSSSETSSTQATSSSTTSTSSSTSTATVTSTPSSTSIGTSTHYTTRVVTQSVVSQ
ANQQASTIFTTRTSVYATVSSTSSSTSSLLNGKSSSSKSKGLSGGAIAGVVVGVVCGT
VALLALALFFFVWKKRRQSSQHVDLEETKQYQPYSLGDADANPVIPPSASSTNWHIPS
RNNTALSKNTASTFATYDLPTRAPGGRDSIITGDAHNISKRSHFPSVVYEEPPSIYNG
NQRFSATSLPDMMEERQLHIVNPDNVSSNIGSNVSDGDDDYDDAKDSNNSSLR"
gene 107687..108274
/gene="POP3"
/locus_tag="YNL282W"
/db_xref="GeneID:855439"
mRNA 107687..108274
/gene="POP3"
/locus_tag="YNL282W"
/product="Pop3p"
/transcript_id="NM_001183120.1"
/db_xref="GI:296147498"
/db_xref="GeneID:855439"
CDS 107687..108274
/gene="POP3"
/locus_tag="YNL282W"
/note="Subunit of both RNase MRP and nuclear RNase P;
RNase MRP cleaves pre-rRNA, while nuclear RNase P cleaves
tRNA precursors to generate mature 5' ends and facilitates
turnover of nuclear RNAs"
/codon_start=1
/product="Pop3p"
/protein_id="NP_014117.1"
/db_xref="GI:6324047"
/db_xref="SGD:S000005226"
/db_xref="GeneID:855439"
/translation="MSGSLKSLDKKIAKRRQVYKPVLDNPFTNEAHMWPRVHDQPLIW
QLLQSSIINKLIHIQSKENYPWELYTDFNEIVQYLSGAHGNSDPVCLFVCNKDPDVPL
VLLQQIPLLCYMAPMTVKLVQLPKSAMDTFKSVSKYGMLLLRCDDRVDKKFVSQIQKN
VDLLQFPWLNAIKYRPTSVKLLKTTVPIVSKKRQK"
gene 108467..108928
/gene="HCH1"
/locus_tag="YNL281W"
/db_xref="GeneID:855440"
mRNA 108467..108928
/gene="HCH1"
/locus_tag="YNL281W"
/product="Hch1p"
/transcript_id="NM_001183119.1"
/db_xref="GI:296147499"
/db_xref="GeneID:855440"
CDS 108467..108928
/gene="HCH1"
/locus_tag="YNL281W"
/note="Heat shock protein regulator; binds to Hsp90p and
may stimulate ATPase activity; originally identified as a
high-copy number suppressor of a HSP90 loss-of-function
mutation; GFP-fusion protein localizes to the cytoplasm
and nucleus; protein abundance increases in response to
DNA replication stress"
/codon_start=1
/product="Hch1p"
/protein_id="NP_014118.1"
/db_xref="GI:6324048"
/db_xref="SGD:S000005225"
/db_xref="GeneID:855440"
/translation="MVVLNPNNWHWVDKNTLPWSKDYLNGKLTSLSTVSSDGKSKIEL
TQVSSITGDSNVSQRKGKPICYFDLQLSMNVKVTNLDTNKDDEDDDGILADGKLEIPE
FMHDESDIPILSQGFDAFDGLVRSEFVPKVVETLLKYQDDLIKEHSKDIQV"
gene complement(109095..110411)
/gene="ERG24"
/locus_tag="YNL280C"
/db_xref="GeneID:855441"
mRNA complement(109095..110411)
/gene="ERG24"
/locus_tag="YNL280C"
/product="delta(14)-sterol reductase"
/transcript_id="NM_001183118.1"
/db_xref="GI:296147500"
/db_xref="GeneID:855441"
CDS complement(109095..110411)
/gene="ERG24"
/locus_tag="YNL280C"
/EC_number="1.3.1.70"
/note="C-14 sterol reductase, acts in ergosterol
biosynthesis; mutants accumulate the abnormal sterol
ignosterol (ergosta-8,14 dienol), and are viable under
anaerobic growth conditions but inviable on rich medium
under aerobic conditions"
/codon_start=1
/product="delta(14)-sterol reductase"
/protein_id="NP_014119.1"
/db_xref="GI:6324049"
/db_xref="SGD:S000005224"
/db_xref="GeneID:855441"
/translation="MVSALNPRTTEFEFGGLIGALGISIGLPVFTIILNQMIRPDYFI
KGFFQNFDIVELWNGIKPLRYYLGNRELWTVYCLWYGILAVLDVILPGRVMKGVQLRD
GSKLSYKINGIAMSTTLVLVLAIRWKLTDGQLPELQYLYENHVSLCIISILFSFFLAT
YCYVASFIPLIFKKNGNGKREKILALGGNSGNIIYDWFIGRELNPRLGPLDIKMFSEL
RPGMLLWLLINLSCLHHHYLKTGKINDALVLVNFLQGFYIFDGVLNEEGVLTMMDITT
DGFGFMLAFGDLSLVPFTYSLQARYLSVSPVELGWVKVVGILAIMFLGFHIFHSANKQ
KSEFRQGKLENLKSIQTKRGTKLLCDGWWAKSQHINYFGDWLISLSWCLATWFQTPLT
YYYSLYFATLLLHRQQRDEHKCRLKYGENWEEYERKVPYKIIPYVY"
gene 110917..112902
/gene="PRM1"
/locus_tag="YNL279W"
/db_xref="GeneID:855442"
mRNA 110917..112902
/gene="PRM1"
/locus_tag="YNL279W"
/product="Prm1p"
/transcript_id="NM_001183117.1"
/db_xref="GI:296147501"
/db_xref="GeneID:855442"
CDS 110917..112902
/gene="PRM1"
/locus_tag="YNL279W"
/note="Pheromone-regulated multispanning membrane protein
involved in membrane fusion during mating; predicted to
have 5 transmembrane segments and a coiled coil domain;
localizes to the shmoo tip; regulated by Ste12p"
/codon_start=1
/product="Prm1p"
/protein_id="NP_014120.1"
/db_xref="GI:6324050"
/db_xref="SGD:S000005223"
/db_xref="GeneID:855442"
/translation="MSGFKCYLQLGDRLSQIWLNKYTLVLLLAMLKLLFFSKSIQHAI
EVSETYILSNCYSIDSLYSKMTDNTPHYLGIMGNYLIEKGMEETVKATLETLSLIVYA
SEGLVNFAIDLYLGTYACLIVSAVDGTVDVATNITEKLISLVNDTVSSVANELDTGLN
DISKIINKVIKAASKVENFFTGDDDDSNMTSSIKSVNLTISALHNLYIPSSINDKLEE
LSAKTPDFAQVKNTTKNLISVPFNEVRKNIKAVNASNIIGDTSVLYVPPVSLDNSTGI
CSSNQSEILAFYSILGHVLKIATVVCITVLICFAVGAMAPVAWNEIKLWRRLCGMRDH
YMLSRQDSYTSFSSENTHELKDPFRDPPIQNGQYDVIASYQQCFQTWNTRIAGWMTNL
VTFGKSPENIDPKTKQKIEWVVAYMTSERALCVLGIGLLGILVCICQFVMIALLKHKI
SHSLTSNDGDGVQNLLKSSTAVDIENQMSLWSVQTNKYINTTETNINQEVFGWINTTT
LSVNNTVATMISDIDTTLADVFNGTLLYNPMKTVVGCAIENKLYTIEKAMTWIHDKAQ
LHIPRINGTQIKQALAKQTDNSTIPTASSTSAATENLLENLVNDMREGLLKILRAYHR
ITLGELTVALVILAVWLVQLPIALVILRLRLRKATFD"
gene 113271..116453
/gene="CAF120"
/locus_tag="YNL278W"
/db_xref="GeneID:855443"
mRNA 113271..116453
/gene="CAF120"
/locus_tag="YNL278W"
/product="Caf120p"
/transcript_id="NM_001183116.1"
/db_xref="GI:296147502"
/db_xref="GeneID:855443"
CDS 113271..116453
/gene="CAF120"
/locus_tag="YNL278W"
/note="Part of the evolutionarily-conserved CCR4-NOT
transcriptional regulatory complex involved in controlling
mRNA initiation, elongation, and degradation"
/codon_start=1
/product="Caf120p"
/protein_id="NP_014121.1"
/db_xref="GI:6324051"
/db_xref="SGD:S000005222"
/db_xref="GeneID:855443"
/translation="MRIFSGDNKVVDSLASNPGLMSPSNFGGDFGSRLKVNVTSKKKL
NDSSPTSPMESSPVSPELVPILTLLNAHTHRRYHEGVFLILQDLNNNGTHAARKWKDV
YGVLLGTQLALWDAKELAEFTDPSCPVSEKKLKEVASKPTYINLTDATLRTLDNSDNI
VMECGKNLTNALVVSTTLKNRYFLQFGNKESFNAWNSAIRLCLYECSSLQEAYTGAFI
SSRGAKLGDIRILLTNRKYDYKDWVSVRFGAGMPWKRCYAVISQSSSKKKGHFGEINL
YENDKKVKKNHAMATIVEAKALYAVYPSSPKLIDSSTIIKVVGSVKFEKKESAQEKDV
FIMPEKHQAVPSYDTIIRFLIPAMDTFKLYGRPEKLLSSKNDPHSLLFGLPVLPHIYY
LEVEDLLPLTNSVSSLHWSNNEWKEHISDILQRKIAQGYCGCNSTSNITSPLPSPFLG
SADLFERADGVLSPKLSYGSKSSSNNSSKNSLPKRERVKLSSSSEQDLNNSDSPSIKR
KSPPLVISESPHKVHTPTDASFRTRVTEGSPYAKQRHPKPFASSVNDSPSDRAKSRTV
PYNNNDRKATTPEKFERGETSCGKNVDESLEKVRNMKLEIPESNFDKFMTDKNLLSVD
SKCSNEKKLSVESDLSAIYEKYSNGPFGHTEGLNGSSDETYLRFQRASVHSESNYNSR
KSFTPSDFSNGNEEEHAVLQELNSLTQRINELGMESINSNSDSDRINGSYSQVDFGNN
NDEDDMNLFDPDFMAQDQLRAEERDYNKDDRTPLAKVPAAFQSTGLGITPDDDIERQY
ITEHRSRHEVPKRSPEKPSNPLEIGNPYAKPGTRLNTTHTHSKTDRSITPQRGQPVPS
GQQISSYVQPANINSPNKMYGANNSAMGSPRNPKTRAPPGPYNQGWNNRPSPSNIYQR
PHPSDTQPQAYHLPGNPYSTGNRPNMQAQYHPQQVPMPILQQPNRPYQPYAMNTHMGS
PGGYAGAAPPFQPANVNYNTRPQQPWPTPNSPSAHYRPPPNLNQPQNGSAGYYRPPAP
QLQNSQARPQKKDGFSQFMPSATTKNPYAQ"
gene 116679..116867
/locus_tag="YNL277W-A"
/db_xref="GeneID:1466509"
mRNA 116679..116867
/locus_tag="YNL277W-A"
/product="hypothetical protein"
/transcript_id="NM_001184664.1"
/db_xref="GI:296147503"
/db_xref="GeneID:1466509"
CDS 116679..116867
/locus_tag="YNL277W-A"
/codon_start=1
/product="hypothetical protein"
/protein_id="NP_878151.1"
/db_xref="GI:33438863"
/db_xref="SGD:S000028852"
/db_xref="GeneID:1466509"
/translation="MTLAYYGQPVKMCHILPPLRSLPVLVGKKKLKKKKSQTTNNHVI
FLFTLFIKLLKTHNRMSL"
gene 117349..118809
/gene="MET2"
/locus_tag="YNL277W"
/db_xref="GeneID:855444"
mRNA 117349..118809
/gene="MET2"
/locus_tag="YNL277W"
/product="homoserine O-acetyltransferase"
/transcript_id="NM_001183115.1"
/db_xref="GI:296147504"
/db_xref="GeneID:855444"
CDS 117349..118809
/gene="MET2"
/locus_tag="YNL277W"
/EC_number="2.3.1.31"
/note="L-homoserine-O-acetyltransferase, catalyzes the
conversion of homoserine to O-acetyl homoserine which is
the first step of the methionine biosynthetic pathway"
/codon_start=1
/product="homoserine O-acetyltransferase"
/protein_id="NP_014122.1"
/db_xref="GI:6324052"
/db_xref="SGD:S000005221"
/db_xref="GeneID:855444"
/translation="MSHTLKSKTLQELDIEEIKETNPLLKLVQGQRIVQVPELVLESG
VVINNFPIAYKTWGTLNEAGDNVLVICHALTGSADVADWWGPLLGNDLAFDPSRFFII
CLNSMGSPYGSFSPLTINEETGVRYGPEFPLCTVRDDVRAHRIVLDSLGVKSIACVIG
GSMGGMLSLEWAAMYGKEYVKNMVALATSARHSAWCISWSEAQRQSIYSDPNYLDGYY
PVEEQPVAGLSAARMSALLTYRTRNSFENKFSRRSPSIAQQQKAQREETRKPSTVSEH
SLQIHNDGYKTKASTAIAGISGQKGQSVVSTASSSDSLNSSTSMTSVSSVTGEVKDIK
PAQTYFSAQSYLRYQGTKFINRFDANCYIAITRKLDTHDLARDRVDDITEVLSTIQQP
SLIIGIQSDGLFTYSEQEFLAEHIPKSQLEKIESPEGHDAFLLEFKLINKLIVQFLKT
NCKAITDAAPRAWGGDVGNDETKTSVFGEAEEVTNW"
gene 119268..120998
/gene="BOR1"
/locus_tag="YNL275W"
/db_xref="GeneID:855446"
mRNA 119268..120998
/gene="BOR1"
/locus_tag="YNL275W"
/product="Bor1p"
/transcript_id="NM_001183113.1"
/db_xref="GI:296147505"
/db_xref="GeneID:855446"
CDS 119268..120998
/gene="BOR1"
/locus_tag="YNL275W"
/note="Boron efflux transporter of the plasma membrane;
binds HCO3-, I-, Br-, NO3- and Cl-; has similarity to the
characterized boron efflux transporter A. thaliana BOR1"
/codon_start=1
/product="Bor1p"
/protein_id="NP_014124.1"
/db_xref="GI:6324054"
/db_xref="SGD:S000005219"
/db_xref="GeneID:855446"
/translation="MSNESTRVTVSRGCTASDECAQALERTNDELDRESSVSESRSDE
ESHEKLSRRRFPTLGIGIWLDLKDRIPYYKSDWVDAFNYRVIPSIVDTYFNNLLPAIA
FAQDMFDRTDNSYGVNEVLLSSAMAGIVFGVLGGQPLCIVGVTGPISIFNYTVYEIIK
PLNTSYFGFMFWICMWSMIFHLVLAFTNAVCLLQYVTTFPCDIFGLFINVVYIQKGIQ
ILTRQFSAKSGEKSVQDGFASVVVALVMTAFGLFFKLFHYYPLFSHRIRTFISDYSTA
LSVLFWSSFTHFGGYLHDVKFKKLPITKAFFPTSKVNRPQNTWLAYEPIPVKDVFIAL
PFGIFLTILFYFDHNVSSLMAQRHQYKLKKPSSFHYDFALLGLTTCISGVLGIPAPNG
LIPQAPLHTETLLVRDSNQKVISCVEQRFTNTFQGLMILGTMTRPLLVCLGEIPQAVL
SGLFFIMGINGLMTNSIIQRLVFLFSDPNRRDNTSPLMKVSKKSMLIFLSFSLTGFAG
EFAITNTIAAIGFPLVLLLSVLVSFSFAYIFPTEELKILDTNVAQKFTIKNLLLENIR
DAKFCDKHED"
gene complement(121118..122170)
/gene="GOR1"
/locus_tag="YNL274C"
/db_xref="GeneID:855447"
mRNA complement(121118..122170)
/gene="GOR1"
/locus_tag="YNL274C"
/product="Gor1p"
/transcript_id="NM_001183112.1"
/db_xref="GI:296147506"
/db_xref="GeneID:855447"
CDS complement(121118..122170)
/gene="GOR1"
/locus_tag="YNL274C"
/EC_number="1.-.-.-"
/note="Glyoxylate reductase; null mutation results in
increased biomass after diauxic shift; the authentic,
non-tagged protein is detected in highly purified
mitochondria in high-throughput studies; protein abundance
increases in response to DNA replication stress"
/codon_start=1
/product="Gor1p"
/protein_id="NP_014125.1"
/db_xref="GI:6324055"
/db_xref="SGD:S000005218"
/db_xref="GeneID:855447"
/translation="MSKKPIVLKLGKDAFGDQAWGELEKIADVITIPESTTREQFLRE
VKDPQNKLSQVQVITRTARSVKNTGRFDEELALALPSSVVAVCHTGAGYDQIDVEPFK
KRHIQVANVPDLVSNATADTHVFLLLGALRNFGIGNRRLIEGNWPEAGPACGSPFGYD
PEGKTVGILGLGRIGRCILERLKPFGFENFIYHNRHQLPSEEEHGCEYVGFEEFLKRS
DIVSVNVPLNHNTHHLINAETIEKMKDGVVIVNTARGAVIDEQAMTDALRSGKIRSAG
LDVFEYEPKISKELLSMSQVLGLPHMGTHSVETRKKMEELVVENAKNVILTGKVLTIV
PELQNEDWPNESKPLV"
gene 122883..126599
/gene="TOF1"
/locus_tag="YNL273W"
/db_xref="GeneID:855448"
mRNA 122883..126599
/gene="TOF1"
/locus_tag="YNL273W"
/product="Tof1p"
/transcript_id="NM_001183111.1"
/db_xref="GI:296147507"
/db_xref="GeneID:855448"
CDS 122883..126599
/gene="TOF1"
/locus_tag="YNL273W"
/note="Subunit of a replication-pausing checkpoint complex
(Tof1p-Mrc1p-Csm3p) that acts at the stalled replication
fork to promote sister chromatid cohesion after DNA
damage, facilitating gap repair of damaged DNA; interacts
with the MCM helicase"
/codon_start=1
/product="Tof1p"
/protein_id="NP_014126.1"
/db_xref="GI:6324056"
/db_xref="SGD:S000005217"
/db_xref="GeneID:855448"
/translation="MSADLQQGTTNAADFSLTVLRARIALLATAIGGPDYTSQIDPPP
YKLGDDCLACLKDLKRWFKLVDDQQKRWDVAMAVAEYRILTDDLLPILIDWENKCSLA
AKLAKNNPDHEEFRNKAYYDKIALNCLQLLVLMTWPLIVTEQSSSNQITLYGELKKHQ
LVYKKTILSMESGKVLRAAIRLALDVIKIDRLSRTPRDNMVLKLVLNFFRNVIAIEPG
EFTINTKKSMPKKGITSIDTLPPNVSMDDISLNTVISSFHKNKVFGFLLTLTSSLSKE
FDQDFINIPLLEIMFYFTKDVNQELLFPRQFETGTHSKVVNKNESSSANNIVTSAGFE
LSKLLQKEHQMRKNVIKHTSARHSRFGGLLSIQTPDKTRLTVSGSQALVDEKIALQKL
DDSKKWNKRIIKKHQSVAAEGLPNSLLNSQTGKAIFFTESNGKHFKEFINNFIDSGFN
ILLHSVTNYFTTEQDRMVTLEQVEYLLFFAWFVKYQLLRSKIDNSADIKQVSEALKEV
TFILVSSLLRSAYDLKNWTVTHAGMIAFNELLNLVSRTKAAQEEDSTDIEFIVSRLFS
DERIQLLSNLPKIGSKYSLQFMKSCIELTHSVLKVLEQYSDDKTLVIEGKSRRQKKFN
ISEGDITKLIEEENVDRDEALDILTSSLRSIEVNFQKVQANYMTEPVIETYINFLERF
RELEDDSIKKVFSFFHRVFVQAKEQALLFRFDLIILLREMLSPDGLDRMSRSRKYVSQ
FSDYFLARLKKRLKKSPAWFVGLLFPPLHNSEVGFYQRYGEYNVLNNESMYAAPASQF
KPIPDEEALPPSILLDMKYGVLVSTLLDDGKTELLDQLLKHITHTLDIFKSWLTVNVN
AGKETVNPPNEYFTLTGVLNNDPIFKDKDYRALLLLIGYSIPRKINEPCFLPGTVEVS
DLTVSCELVKKYLSTPFETPNGLPSSSYLLRVRSEKDSFSHNEQDGWEGDDDYDYNDP
YIVPDDQILSKSDAAYFKDLDNNASDKLKGTKFSKGIARSKKKDKRKRRKGEAKTNLP
MFGDQDDERPQTVRERHGVFSKEFISDSEDDEDLMNPIFFENETYMRWLLDKNNGQLT
EDRYIQFAKFAAERMNNGGVVTGDYTSLFGGSIPSIESIRATESSSFAPDKSLISLAS
HVASEMSIFDVNNNNNNQLSDDDVNSESRNSLGSSQPSNSQNMFQSEVYSRKESTKRS
LEASAADESDEDEEAIRLFGKKSRVVLSQGDSDD"
rep_origin 126599..126805
/note="ARS1410;
Replication origin; identified in multiple array studies,
confirmed by plasmid-based recombinational ARS assay"
/db_xref="SGD:S000130141"
gene complement(126805..129084)
/gene="SEC2"
/locus_tag="YNL272C"
/db_xref="GeneID:855449"
mRNA complement(126805..129084)
/gene="SEC2"
/locus_tag="YNL272C"
/product="Sec2p"
/transcript_id="NM_001183110.1"
/db_xref="GI:296147508"
/db_xref="GeneID:855449"
CDS complement(126805..129084)
/gene="SEC2"
/locus_tag="YNL272C"
/note="Guanyl-nucleotide exchange factor for the small
G-protein Sec4p; essential for post-Golgi vesicle
transport and for autophagy; associates with the exocyst,
via exocyst subunit Sec15p, on secretory vesicles"
/codon_start=1
/product="Sec2p"
/protein_id="NP_014127.1"
/db_xref="GI:6324057"
/db_xref="SGD:S000005216"
/db_xref="GeneID:855449"
/translation="MDASEEAKRVSIQVTSLSTQLIESVDKQSHLEEQLNKSLKTIAS
QKAAIENYNQLKEDYNTLKRELSDRDDEVKRLREDIAKENELRTKAEEEADKLNKEVE
DLTASLFDEANNMVADARKEKYAIEILNKRLTEQLREKDTLLDTLTLQLKNLKKVMHS
LDNESTVTNNSNRYSTILSDSATSSSTSLNKVPTSYSLASQDIYSGIVYSPSISSIRY
DISLYNEFLKFVAALPRCENIKATSTESKLIRRLVNDEIQPILKIDNASGIGWLVKKT
LLSLIIDGLVVVEPLSGVNATYQIGYNSSSPAKQATSNMPKMFKFPLDSPPVAVHAAC
SFCGESRDDIIEHARMYILKTLHKTDDGKEQVTNTYPLCHWCLLKLRQTCEIFAFLRS
LKVGAWHLEKLTTQNITKEDLEKFSEVTKHTKRDGRVSSQDKKTKRLSFMAGLGINSS
TKNKPKMEIFSSETNAKPGQPTTNIQRAWLQLCKLRCILHWTHIGIWAVDDSISSKIG
PLVEDDSDEDQNDAISVRLQDKALWKQDAKRPFSSSSAEESQKSDAFDFESGDMENEI
TGESSSDESSSDGSSTDNSTADSSSEDESSLADSTTSSADSSSPESIDNGEGDDTVTK
DDKSSIKSANNNEENSDCGDKKGRSIIKKKAPQRKIQKKKLLQDLDDLEEQFREESAI
DQTEFENAESNVKQNISSKRASSGDENSKKDNNEKTLKTNLTIGDKTQEQIGENSPSS
GLHASSSNDDNFDDAQEQQ"
gene complement(129522..135383)
/gene="BNI1"
/locus_tag="YNL271C"
/gene_synonym="PPF3; SHE5"
/db_xref="GeneID:855450"
mRNA complement(129522..135383)
/gene="BNI1"
/locus_tag="YNL271C"
/gene_synonym="PPF3; SHE5"
/product="Bni1p"
/transcript_id="NM_001183109.2"
/db_xref="GI:330443691"
/db_xref="GeneID:855450"
CDS complement(129522..135383)
/gene="BNI1"
/locus_tag="YNL271C"
/gene_synonym="PPF3; SHE5"
/note="Formin, nucleates the formation of linear actin
filaments, involved in cell processes such as budding and
mitotic spindle orientation which require the formation of
polarized actin cables, functionally redundant with BNR1"
/codon_start=1
/product="Bni1p"
/protein_id="NP_014128.2"
/db_xref="GI:330443692"
/db_xref="SGD:S000005215"
/db_xref="GeneID:855450"
/translation="MLKNSGSKHSNSKESHSNSSSGIFQNLKRLANSNATNSNTGSPT
YASQQQHSPVGNEVSTSPASSSSFRKLNAPSRSTSTEARPLNKKSTLNTQNLSQYMNG
KLSGDVPVSSQHARSHSMQSKYSYSKRNSSQASNKLTRQHTGQSHSASSLLSQGSLTN
LSKFTTPDGKIYLEMPSDPYEVEVLFEDIMYKRNIFQSLSEDKQEALMGYSIEKKWLI
VKQDLQNELKKMRANTTSSSTASRTSMASDHHPILTANSSLSSPKSVLMTSASSPTST
VYSNSLNHSTTLSSVGTSTSKGKKLVSGSLKKQPSLNNIYRGGAENNTSASTLPGDRT
NRPPIHYVQRILADKLTSDEMKDLWVTLRTEQLDWVDAFIDHQGHIAMANVLMNSIYK
TAPRENLTKELLEKENSFFKCFRVLSMLSQGLYEFSTHRLMTDTVAEGLFSTKLATRK
MATEIFVCMLEKKNKSRFEAVLTSLDKKFRIGQNLHMIQNFKKMPQYFSHLTLESHLK
IIQAWLFAVEQTLDGRGKMGSLVGASDEFKNGGGENAILEYCQWTMVFINHLCSCSDN
INQRMLLRTKLENCGILRIMNKIKLLDYDKVIDQIELYDNNKLDDFNVKLEANNKAFN
VDLHDPLSLLKNLWDICKGTENEKLLVSLVQHLFLSSSKLIEENQNSSKLTKQLKLMD
SLVTNVSVASTSDEETNMNMAIQRLYDAMQTDEVARRAILESRALTKKLEEIQAERDS
LSEKLSKAEHGLVGQLEDELHERDRILAKNQRVMQQLEAELEELKKKHLLEKHQQEVE
LRKMLTILNSRPEESFNKNEGTRGMNSSLNSSEKANIQKVLQDGLSRAKKDYKDDSKK
FGMTLQPNKRLKMLRMQMENIENEARQLEMTNFAEFEKDRLEPPIHIKKPKVKKMKNK
DRKPLVKPQEADVNKLNDLRRALAEIQMESNDISKFNVEERVNELFNEKKSLALKRLK
ELETKYKGFGIDFNVDEIMDSPKKNTGDVETEEDANYASLDPKTYQKKLDEINRITDQ
LLDIQTQTEHEIQVEEDGESDLSSSSSDDESEEIYQDASPTQELRSEHSELSSGSGPG
SFLDALSQKYGTGQNVTASAAFGENNNGSGIGPLHSKVEKTFMNRLRKSTVSSAPYLE
ELTQKVNKVEPYEQNEDEGLDKKSLPENSTASAASAFDKAEKDMRQHVENGKQGRVVN
HEEDKTADFSAVSKLNNTDGAEDLSTQSSVLSSQPPPPPPPPPPVPAKLFGESLEKEK
KSEDDTVKQETTGDSPAPPPPPPPPPPPPMALFGKPKGETPPPPPLPSVLSSSTDGVI
PPAPPMMPASQIKSAVTSPLLPQSPSLFEKYPRPHKKLKQLHWEKLDCTDNSIWGTGK
AEKFADDLYEKGVLADLEKAFAAREIKSLASKRKEDLQKITFLSRDISQQFGINLHMY
SSLSVADLVKKILNCDRDFLQTPSVVEFLSKSEIIEVSVNLARNYAPYSTDWEGVRNL
EDAKPPEKDPNDLQRADQIYLQLMVNLESYWGSRMRALTVVTSYEREYNELLAKLRKV
DKAVSALQESDNLRNVFNVILAVGNFMNDTSKQAQGFKLSTLQRLTFIKDTTNSMTFL
NYVEKIVRLNYPSFNDFLSELEPVLDVVKVSIEQLVNDCKDFSQSIVNVERSVEIGNL
SDSSKFHPLDKVLIKTLPVLPEARKKGDLLEDEVKLTIMEFESLMHTYGEDSGDKFAK
ISFFKKFADFINEYKKAQAQNLAAEEEERLYIKHKKIVEEQQKRAQEKEKQKENSNSP
SSEGNEEDEAEDRRAVMDKLLEQLKNAGPAKSDPSSARKRALVRKKYLSEKDNAPQLL
NDLDTEEGSILYSPEAMDPTADTVIHAESPTPLATRGVMNTSEDLPSPSKTSALEDQE
EISDRARMLLKELRGSDTPVKQNSILDEHLEKLRARKERSIGEASTGNRLSFK"
gene complement(135940..137661)
/gene="ALP1"
/locus_tag="YNL270C"
/gene_synonym="APL1"
/db_xref="GeneID:855451"
mRNA complement(135940..137661)
/gene="ALP1"
/locus_tag="YNL270C"
/gene_synonym="APL1"
/product="Alp1p"
/transcript_id="NM_001183108.1"
/db_xref="GI:296147510"
/db_xref="GeneID:855451"
CDS complement(135940..137661)
/gene="ALP1"
/locus_tag="YNL270C"
/gene_synonym="APL1"
/note="Arginine transporter; expression is normally very
low and it is unclear what conditions would induce
significant expression"
/codon_start=1
/product="Alp1p"
/protein_id="NP_014129.1"
/db_xref="GI:6324059"
/db_xref="SGD:S000005214"
/db_xref="GeneID:855451"
/translation="MDETVNIQMSKEGQYEINSSSIIKEEEFVDEQYSGENVTKAITT
ERKVEDDAAKETESSPQERREVKRKLKQRHIGMIALGGTIGTGLIIGIGPPLAHAGPV
GALISYLFMGTVIYSVTQSLGEMVTFIPVTSSFSVFAQRFLSPALGATNGYMYWLSWC
FTFALELSVLGKVIQYWTEAVPLAAWIVIFWCLLTSMNMFPVKYYGEFEFCIASIKVI
ALLGFIIFSFCVVCGAGQSDGPIGFRYWRNPGAWGPGIISSDKNEGRFLGWVSSLINA
AFTYQGTELVGITAGEAANPRKALPRAIKKVVVRILVFYILSLFFIGLLVPYNDPKLD
SDGIFVSSSPFMISIENSGTKVLPDIFNAVVLITILSAGNSNVYIGSRVLYSLSKNSL
APRFLSNVTRGGVPYFSVLSTSVFGFLAFLEVSAGSGKAFNWLLNITGVAGFFAWLLI
SFSHIRFMQAIRKRGISRDDLPYKAQMMPFLAYYASFFIALIVLIQGFTAFAPTFQPI
DFVAAYISIFLFLAIWLSFQVWFKCRLLWKLQDIDIDSDRRQIEELVWIEPECKTRWQ
RVWDVLS"
gene 137699..138094
/gene="BSC4"
/locus_tag="YNL269W"
/db_xref="GeneID:855452"
mRNA 137699..138094
/gene="BSC4"
/locus_tag="YNL269W"
/product="Bsc4p"
/transcript_id="NM_001183107.1"
/db_xref="GI:296147511"
/db_xref="GeneID:855452"
CDS 137699..138094
/gene="BSC4"
/locus_tag="YNL269W"
/note="hypothetical protein, ORF exhibits genomic
organization compatible with a translational
readthrough-dependent mode of expression; readthrough is
increased upon depletion of Sup35p"
/codon_start=1
/product="Bsc4p"
/protein_id="NP_014130.1"
/db_xref="GI:6324060"
/db_xref="SGD:S000005213"
/db_xref="GeneID:855452"
/translation="MSIVLRKSNKKNKNCITSKFYTIHIIKISTPVFRAPIAIGESPY
VEWSCLQVVFRKDMVTKKTTFAQLITRLNHFLCQALKRRDSKTYILCRTAVFGAMTPF
SPRKSHINNKLPMQPRKKKIVIIYVVRFH"
gene 138550..140385
/gene="LYP1"
/locus_tag="YNL268W"
/db_xref="GeneID:855453"
mRNA 138550..140385
/gene="LYP1"
/locus_tag="YNL268W"
/product="Lyp1p"
/transcript_id="NM_001183106.1"
/db_xref="GI:296147512"
/db_xref="GeneID:855453"
CDS 138550..140385
/gene="LYP1"
/locus_tag="YNL268W"
/note="Lysine permease; one of three amino acid permeases
(Alp1p, Can1p, Lyp1p) responsible for uptake of cationic
amino acids"
/codon_start=1
/product="Lyp1p"
/protein_id="NP_014131.1"
/db_xref="GI:6324061"
/db_xref="SGD:S000005212"
/db_xref="GeneID:855453"
/translation="MGRFSNIITSNKWDEKQNNIGEQSMQELPEDQIEHEMEAIDPSN
KTTPYSIDEKQYNTKKKHGSLQGGAIADVNSITNSLTRLQVVSHETDINEDEEEAHYE
DKHVKRALKQRHIGMIALGGTIGTGLFVGISTPLSNAGPVGSLIAYIFMGTIVYFVTQ
SLGEMATFIPVTSSITVFSKRFLSPAFGVSNGYMYWFNWAITYAVEVSVIGQVIEYWT
DKVPLAAWIAIFWVIITLMNFFPVKVYGEFEFWVASVKVLAIMGYLIYALIIVCGGSH
QGPIGFRYWRNPGAWGPGIISSDKSEGRFLGWVSSLINAAFTYQGTELVGITAGEAAN
PRKTVPRAINKVVFRIVLFYIMSLFFIGLLVPYNDSRLSASSAVIASSPFVISIQNAG
TYALPDIFNAVVLITVVSAANSNVYVGSRVLYSLARTGNAPKQFGYVTRQGVPYLGVV
CTAALGLLAFLVVNNNANTAFNWLINISTLAGLCAWLFISLAHIRFMQALKHRGISRD
DLPFKAKLMPYGAYYAAFFVTVIIFIQGFQAFCPFKVSEFFTSYISLILLAVVFIGCQ
IYYKCRFIWKLEDIDIDSDRREIEAIIWEDDEPKNLWEKFWAAVA"
gene 140878..144078
/gene="PIK1"
/locus_tag="YNL267W"
/gene_synonym="PIK120; PIK41"
/db_xref="GeneID:855454"
mRNA 140878..144078
/gene="PIK1"
/locus_tag="YNL267W"
/gene_synonym="PIK120; PIK41"
/product="1-phosphatidylinositol 4-kinase"
/transcript_id="NM_001183105.1"
/db_xref="GI:296147513"
/db_xref="GeneID:855454"
CDS 140878..144078
/gene="PIK1"
/locus_tag="YNL267W"
/gene_synonym="PIK120; PIK41"
/EC_number="2.7.1.67"
/note="Phosphatidylinositol 4-kinase; catalyzes first step
in the biosynthesis of
phosphatidylinositol-4,5-biphosphate; may control
cytokinesis through the actin cytoskeleton"
/codon_start=1
/product="1-phosphatidylinositol 4-kinase"
/protein_id="NP_014132.1"
/db_xref="GI:6324062"
/db_xref="SGD:S000005211"
/db_xref="GeneID:855454"
/translation="MHKASSSKKSFDDTIELKKNEQLLKLINSSEFTLHNCVELLCKH
SENIGIHYYLCQKLATFPHSELQFYIPQLVQVLVTMETESMALEDLLLRLRAENPHFA
LLTFWQLQALLTDLSTDPASYGFQVARRVLNNLQTNLFNTSSGSDKNVKIHENVAPAL
VLSSMIMSAIAFPQLSEVTKPLVESQGRRQKAFVFKLARSAMKDFTKNMTLKNTLLNK
KTSRSKRVSSNRSSTPTSPIDLIDPIKTKEDASFRKSRHSEVKLDFDIVDDIGNQVFE
ERISSSIKLPKRKPKYLDNSYVHRTYDGKNINRDGSISNTAKALDGNKGDYISPKGRN
DENNEIGNNEDETGGETEEDADALNSDHFTSSMPDLHNIQPRTSSASSASLEGTPKLN
RTNSQPLSRQAFKNSKKANSSLSQEIDLSQLSTTSKIKMLKANYFRCETQFAIALETI
SQRLARVPTEARLSALRAELFLLNRDLPAEVDIPTLLPPNKKGKLHKLVTITANEAQV
LNSAEKVPYLLLIEYLRDEFDFDPTSETNERLLKKISGNQGGLIFDLNYMNRKENNEN
RNESTLTSNNTRSSVYDSNSFNNGASRNEGLSSTSRSDSASTAHVRTEVNKEEDLGDM
SMVKVRNRTDDEAYRNALVIQSAANVPILPDDSQDRSPELNFGSNLDEVLIENGINSK
NIHSQTDALADQMRVSAVMLAQLDKSPQQLSESTKQIRAQIISSMKEVQDKFGYHDLE
ALHGMAGERKLENDLMTGGIDTSYLGEDWATKKERIRKTSEYGHFENWDLCSVIAKTG
DDLRQEAFAYQMIQAMANIWVKEKVDVWVKRMKILITSANTGLVETITNAMSVHSIKK
ALTKKMIEDAELDDKGGIASLNDHFLRAFGNPNGFKYRRAQDNFASSLAAYSVICYLL
QVKDRHNGNIMIDNEGHVSHIDFGFMLSNSPGSVGFEAAPFKLTYEYIELLGGVEGEA
FKKFVELTKSSFKALRKYADQIVSMCEIMQKDNMQPCFDAGEQTSVQLRQRFQLDLSE
KEVDDFVENFLIGKSLGSIYTRIYDQFQLITQGIYS"
gene complement(144280..145281)
/gene="IST1"
/locus_tag="YNL265C"
/db_xref="GeneID:855456"
mRNA complement(join(144280..145149,145255..145281))
/gene="IST1"
/locus_tag="YNL265C"
/product="Ist1p"
/transcript_id="NM_001183103.1"
/db_xref="GI:296147514"
/db_xref="GeneID:855456"
CDS complement(join(144280..145149,145255..145281))
/gene="IST1"
/locus_tag="YNL265C"
/note="Protein with a positive role in the multivesicular
body sorting pathway; functions and forms a complex with
Did2p; recruitment to endosomes is mediated by the
Vps2p-Vps24p subcomplex of ESCRT-III; also interacts with
Vps4p"
/codon_start=1
/product="Ist1p"
/protein_id="NP_014134.1"
/db_xref="GI:6324064"
/db_xref="SGD:S000005209"
/db_xref="GeneID:855456"
/translation="MAPSMIPFTIKLKTCLKMCIQRLRYAQEKQQAIAKQSRRQVAQL
LLTNKEQKAHYRVETLIHDDIHIELLEILELYCELLLARVQVINDISTEEQLVKEHMD
DGINEAIRSLIYAILFVDEVKELSQLKDLMAWKINVEFVNGVIADHIDVPEKIIKKCS
PSVPKEELVDLYLKEIAKTYDVPYSKLENSLSSSSSNISSDFSDPSGDIEDNDEEKPI
LALDNDDNDNADAKHPITVKKPRQNSENIKNELKIPKDIKKEVIEKKQSEKKTTKRKT
KKEQENDELDELKKRFDALRRK"
gene complement(145563..146615)
/gene="PDR17"
/locus_tag="YNL264C"
/gene_synonym="ISS1; SFH4"
/db_xref="GeneID:855457"
mRNA complement(145563..146615)
/gene="PDR17"
/locus_tag="YNL264C"
/gene_synonym="ISS1; SFH4"
/product="Pdr17p"
/transcript_id="NM_001183102.1"
/db_xref="GI:296147515"
/db_xref="GeneID:855457"
CDS complement(145563..146615)
/gene="PDR17"
/locus_tag="YNL264C"
/gene_synonym="ISS1; SFH4"
/note="Phosphatidylinositol transfer protein (PITP),
downregulates Plb1p-mediated turnover of
phosphatidylcholine, found in the cytosol and microsomes,
homologous to Pdr16p, deletion affects phospholipid
composition"
/codon_start=1
/product="Pdr17p"
/protein_id="NP_014135.1"
/db_xref="GI:6324065"
/db_xref="SGD:S000005208"
/db_xref="GeneID:855457"
/translation="MGLFSRKRDHTPAVPKEKLIPCDKIFLDPPAKYGNAPLLEPISE
DQNEKYRAVLRHFQDDDLKLPENLNDLDNGTHANDRPLSDWEKFWLSRECFLRYLRAN
KWNTANAIKGLTKTLVWRREIGLTHGKEDKDPLTADKVAVENETGKQVILGFDNAKRP
LYYMKNGRQNTESSFRQVQELVYMMETATTVAPQGVEKITVLVDFKSYKEPGIITDKA
PPISIARMCLNVMQDHYPERLAKCVLINIPWFAWAFLKMMYPFLDPATKAKAIFDEPF
ENHIEPSQLDALYNGLLDFKYKHEVYWPDMVKKVDDLRLKRFDRFLKFGGIVGLSEYD
TKGQHDELKYPVDMVI"
gene complement(146896..147840)
/gene="YIF1"
/locus_tag="YNL263C"
/db_xref="GeneID:855458"
mRNA complement(146896..147840)
/gene="YIF1"
/locus_tag="YNL263C"
/product="Yif1p"
/transcript_id="NM_001183101.1"
/db_xref="GI:296147516"
/db_xref="GeneID:855458"
CDS complement(146896..147840)
/gene="YIF1"
/locus_tag="YNL263C"
/note="Integral membrane protein required for the fusion
of ER-derived COPII transport vesicles with the Golgi;
interacts with Yip1p and Yos1p; localizes to the Golgi,
the ER, and COPII vesicles; homolog of human YIPF3"
/codon_start=1
/product="Yif1p"
/protein_id="NP_014136.1"
/db_xref="GI:6324066"
/db_xref="SGD:S000005207"
/db_xref="GeneID:855458"
/translation="MSYNPYAYATSEQNGVNDRFSHTPQQQRPMQIPRNTPVNGQGNA
NMNANVNGSGGGFPFQDPRGSMAFQLGQSAFSNFIGQDNFNQFQETVNKATANAAGSQ
QISTYFQVSTRYVINKLKLILVPFLNGTKNWQRIMDSGNFLPPRDDVNSPDMYMPIMG
LVTYILIWNTQQGLKGSFNPEDLYYKLSSTLAFVCLDLLILKLGLYLLIDSKIPSFSL
VELLCYVGYKFVPLILAQLLTNVTMPFNLNILIKFYLFIAFGVFLLRSVKFNLLSRSG
AEDDDIHVSISKSTVKKCNYFLFVYGFIWQNVLMWLMG"
gene 148212..154880
/gene="POL2"
/locus_tag="YNL262W"
/gene_synonym="DUN2"
/db_xref="GeneID:855459"
mRNA 148212..154880
/gene="POL2"
/locus_tag="YNL262W"
/gene_synonym="DUN2"
/product="Pol2p"
/transcript_id="NM_001183100.1"
/db_xref="GI:296147517"
/db_xref="GeneID:855459"
CDS 148212..154880
/gene="POL2"
/locus_tag="YNL262W"
/gene_synonym="DUN2"
/EC_number="2.7.7.7"
/note="Catalytic subunit of DNA polymerase (II) epsilon, a
chromosomal DNA replication polymerase that exhibits
processivity and proofreading exonuclease activity; also
involved in DNA synthesis during DNA repair; interacts
extensively with Mrc1p"
/codon_start=1
/product="Pol2p"
/protein_id="NP_014137.1"
/db_xref="GI:6324067"
/db_xref="SGD:S000005206"
/db_xref="GeneID:855459"
/translation="MMFGKKKNNGGSSTARYSAGNKYNTLSNNYALSAQQLLNASKID
DIDSMMGFERYVPPQYNGRFDAKDIDQIPGRVGWLTNMHATLVSQETLSSGSNGGGNS
NDGERVTTNQGISGVDFYFLDEEGGSFKSTVVYDPYFFIACNDESRVNDVEELVKKYL
ESCLKSLQIIRKEDLTMDNHLLGLQKTLIKLSFVNSNQLFEARKLLRPILQDNANNNV
QRNIYNVAANGSEKVDAKHLIEDIREYDVPYHVRVSIDKDIRVGKWYKVTQQGFIEDT
RKIAFADPVVMAFDIETTKPPLKFPDSAVDQIMMISYMIDGEGFLITNREIISEDIED
FEYTPKPEYPGFFTIFNENDEVALLQRFFEHIRDVRPTVISTFNGDFFDWPFIHNRSK
IHGLDMFDEIGFAPDAEGEYKSSYCSHMDCFRWVKRDSYLPQGSQGLKAVTQSKLGYN
PIELDPELMTPYAFEKPQHLSEYSVSDAVATYYLYMKYVHPFIFSLCTIIPLNPDETL
RKGTGTLCEMLLMVQAYQHNILLPNKHTDPIERFYDGHLLESETYVGGHVESLEAGVF
RSDLKNEFKIDPSAIDELLQELPEALKFSVEVENKSSVDKVTNFEEIKNQITQKLLEL
KENNIRNELPLIYHVDVASMYPNIMTTNRLQPDSIKAERDCASCDFNRPGKTCARKLK
WAWRGEFFPSKMDEYNMIKRALQNETFPNKNKFSKKKVLTFDELSYADQVIHIKKRLT
EYSRKVYHRVKVSEIVEREAIVCQRENPFYVDTVKSFRDRRYEFKGLAKTWKGNLSKI
DPSDKHARDEAKKMIVLYDSLQLAHKVILNSFYGYVMRKGSRWYSMEMAGITCLTGAT
IIQMARALVERVGRPLELDTDGIWCILPKSFPETYFFTLENGKKLYLSYPCSMLNYRV
HQKFTNHQYQELKDPLNYIYETHSENTIFFEVDGPYKAMILPSSKEEGKGIKKRYAVF
NEDGSLAELKGFELKRRGELQLIKNFQSDIFKVFLEGDTLEGCYSAVASVCNRWLDVL
DSHGLMLEDEDLVSLICENRSMSKTLKEYEGQKSTSITTARRLGDFLGEDMVKDKGLQ
CKYIISSKPFNAPVTERAIPVAIFSADIPIKRSFLRRWTLDPSLEDLDIRTIIDWGYY
RERLGSAIQKIITIPAALQGVSNPVPRVEHPDWLKRKIATKEDKFKQTSLTKFFSKTK
NVPTMGKIKDIEDLFEPTVEEDNAKIKIARTTKKKAVSKRKRNQLTNEEDPLVLPSEI
PSMDEDYVGWLNYQKIKWKIQARDRKRRDQLFGNTNSSRERSALGSMIRKQAESYANS
TWEVLQYKDSGEPGVLEVFVTINGKVQNITFHIPKTIYMKFKSQTMPLQKIKNCLIEK
SSASLPNNPKTSNPAGGQLFKITLPESVFLEEKENCTSIFNDENVLGVFEGTITPHQR
AIMDLGASVTFRSKAMGALGKGIQQGFEMKDLSMAENERYLSGFSMDIGYLLHFPTSI
GYEFFSLFKSWGDTITILVLKPSNQAQEINASSLGQIYKQMFEKKKGKIETYSYLVDI
KEDINFEFVYFTDISKLYRRLSQETTKLKEERGLQFLLLLQSPFITKLLGTIRLLNQM
PIVKLSLNEVLLPQLNWQPTLLKKLVNHVLSSGSWISHLIKLSQYSNIPICNLRLDSM
DYIIDVLYARKLKKENIVLWWNEKAPLPDHGGIQNDFDLNTSWIMNDSEFPKINNSGV
YDNVVLDVGVDNLTVNTILTSALINDAEGSDLVNNNMGIDDKDAVINSPSEFVHDAFS
NDALNVLRGMLKEWWDEALKENSTADLLVNSLASWVQNPNAKLFDGLLRYHVHNLTKK
ALLQLVNEFSALGSTIVYADRNQILIKTNKYSPENCYAYSQYMMKAVRTNPMFSYLDL
NIKRYWDLLIWMDKFNFSGLACIEIEEKENQDYTAVSQWQLKKFLSPIYQPEFEDWMM
IILDSMLKTKQSYLKLNSGTQRPTQIVNVKKQDKEDSVENSLNGFSHLFSKPLMKRVK
KLFKNQQEFILDPQYEADYVIPVLPGSHLNVKNPLLELVKSLCHVMLLSKSTILEIRT
LRKELLKIFELREFAKVAEFKDPSLSLVVPDFLCEYCFFISDIDFCKAAPESIFSCVR
CHKAFNQVLLQEHLIQKLRSDIESYLIQDLRCSRCHKVKRDYMSAHCPCAGAWEGTLP
RESIVQKLNVFKQVAKYYGFDILLSCIADLTI"
gene 155100..156539
/gene="ORC5"
/locus_tag="YNL261W"
/db_xref="GeneID:855460"
mRNA 155100..156539
/gene="ORC5"
/locus_tag="YNL261W"
/product="origin recognition complex subunit 5"
/transcript_id="NM_001183099.1"
/db_xref="GI:296147518"
/db_xref="GeneID:855460"
CDS 155100..156539
/gene="ORC5"
/locus_tag="YNL261W"
/note="Subunit of the origin recognition complex, which
directs DNA replication by binding to replication origins
and is also involved in transcriptional silencing"
/codon_start=1
/product="origin recognition complex subunit 5"
/protein_id="NP_014138.1"
/db_xref="GI:6324068"
/db_xref="SGD:S000005205"
/db_xref="GeneID:855460"
/translation="MNVTTPEVAFREYQTNCLASYISADPDITPSNLILQGYSGTGKT
YTLKKYFNANPNLHAVWLEPVELVSWKPLLQAIARTVQYKLKTLYPNIPTTDYDPLQV
EEPFLLVKTLHNIFVQYESLQEKTCLFLILDGFDSLQDLDAALFNKYIKLNELLPKDS
KINIKFIYTMLETSFLQRYSTHCIPTVMFPRYNVDEVSTILVMSRCGELMEDSCLRKR
IIEEQITDCTDDQFQNVAANFIHLIVQAFHSYTGNDIFALNDLIDFKWPKYVSRITKE
NIFEPLALYKSAIKLFLSTDDNLSENGQGESAITTNRDDLENSQTYDLSIISKYLLIA
SYICSYLEPRYDASIFSRKTRIIQGRAAYGRRKKKEVNPRYLQPSLFAIERLLAIFQA
IFPIQGKAESGSLSALREESLMKANIEVFQNLSELHTLKLIATTMNKNIDYLSPKVRW
KVNVPWEIIKEISESVHFNISDYFSDIHE"
gene complement(156859..157455)
/gene="LTO1"
/locus_tag="YNL260C"
/db_xref="GeneID:855461"
mRNA complement(156859..157455)
/gene="LTO1"
/locus_tag="YNL260C"
/product="Lto1p"
/transcript_id="NM_001183098.1"
/db_xref="GI:296147519"
/db_xref="GeneID:855461"
CDS complement(156859..157455)
/gene="LTO1"
/locus_tag="YNL260C"
/note="Essential protein that forms a complex with Rli1p
and Yae1p; ortholog of human ORAOV1, which is
overexpressed in solid tumors; inviability of null mutant
under standard conditions is complemented by
overexpression of ORAOV1; essential for growth under
standard (aerobic) conditions but not under anaerobic
conditions; may have a role in protection of ribosomal
assembly and function from damage due to reactive oxygen
species"
/codon_start=1
/product="Lto1p"
/protein_id="NP_014139.1"
/db_xref="GI:6324069"
/db_xref="SGD:S000005204"
/db_xref="GeneID:855461"
/translation="MVRNRFIRKMKKNLFKSNHLSYLKSKWKVKITGQIKMDFDNLLN
LEEQYYQEGFLEGQNENIKQSFLEGKQYGLQVGFQRFTLLGQMEGLCDVIESYGLHSP
TLEKNIHTIRTLMKGLKMNNDDESVMEFERVLIKLKNKFRTILITLHRLVKDKRTPTV
TFEVFEDVSRAIAGEIRGFVENEDIAKNKTKQNQAQSW"
gene complement(157644..157865)
/gene="ATX1"
/locus_tag="YNL259C"
/db_xref="GeneID:855462"
mRNA complement(157644..157865)
/gene="ATX1"
/locus_tag="YNL259C"
/product="Atx1p"
/transcript_id="NM_001183097.1"
/db_xref="GI:296147520"
/db_xref="GeneID:855462"
CDS complement(157644..157865)
/gene="ATX1"
/locus_tag="YNL259C"
/note="Cytosolic copper metallochaperone that transports
copper to the secretory vesicle copper transporter Ccc2p
for eventual insertion into Fet3p, which is a multicopper
oxidase required for high-affinity iron uptake"
/codon_start=1
/product="Atx1p"
/protein_id="NP_014140.1"
/db_xref="GI:6324070"
/db_xref="SGD:S000005203"
/db_xref="GeneID:855462"
/translation="MAEIKHYQFNVVMTCSGCSGAVNKVLTKLEPDVSKIDISLEKQL
VDVYTTLPYDFILEKIKKTGKEVRSGKQL"
gene complement(158109..160373)
/gene="DSL1"
/locus_tag="YNL258C"
/gene_synonym="RNS1"
/db_xref="GeneID:855463"
mRNA complement(158109..160373)
/gene="DSL1"
/locus_tag="YNL258C"
/gene_synonym="RNS1"
/product="Dsl1p"
/transcript_id="NM_001183096.1"
/db_xref="GI:296147521"
/db_xref="GeneID:855463"
CDS complement(158109..160373)
/gene="DSL1"
/locus_tag="YNL258C"
/gene_synonym="RNS1"
/note="Peripheral membrane protein needed for Golgi-to-ER
retrograde traffic; forms a complex with Sec39p and Tip20p
that interacts with ER SNAREs Sec20p and Use1p; component
of the ER target site that interacts with coatomer;
interacts with Cin5p; similar to the fly and human ZW10
gene"
/codon_start=1
/product="Dsl1p"
/protein_id="NP_014141.1"
/db_xref="GI:6324071"
/db_xref="SGD:S000005202"
/db_xref="GeneID:855463"
/translation="MESLFPNKGEIIRELLKDPLILKNDSKRSNGSELELDSSDLLQR
EAILANELNILDNLKTFLNLIKEVKTNLNILELENCYYSLQSLRKKMRNNAAYLKQSF
NFQQSISTYVDTLHLELVSTLYKILTNGFWKITENSIQFTPTVEWGKDKVHIEYDTFM
DFVAQQYFPKGSLDNQAWFILDMTSADSQEQVRAKLNTIMKEYMNLSRIVSMIKNSIF
ISGKEISYENEKNILVFSKSSSHGQHCVSTVLTSFEAVCDFMLDGLAFRDRKTLSYEL
GPLFNTEFTKFVKNNASIILESLDSPLKNLVSVINNKLTRLVAKSEVTNWTHSGKEIQ
DLLMNKQLYYNLLLDKVLESHISEIRSIFEDPKKSWQNLEVVELTTSNTNTMSEKIGK
NDSDVQNEKELHNAVSKDDDWNWEVEDDDADAWGDEIDVNIDDEEEKTNQEKEKEPEE
EENAWDEAWAIDENIDDASLENGKEHLKAHDVGSLDKDHIEVTQLPKLFLAISQNFKS
SFADSHVDEQYFAYKYNLLQTSYMAMCTANFSHNWCQLYVDMRYLIERDEKLYRIKEL
TRNLLETKLNMKYRIVCQLIRHQLTEFRENERNPSWDATIEKLLPYILKEIVRPLQKI
RGEEGSRYLLSFLNFLYNDCVTKEILKWQIISEVNSENLGELVSLLVNNTDIQLLAKE
PSYKKMREKFATMGKFLPLHLKEIMEMFYNGDFYLFATDELIQWIELLFADTPLRRNA
IDDIYEIRGTALDD"
gene complement(160631..164320)
/gene="SIP3"
/locus_tag="YNL257C"
/db_xref="GeneID:855464"
mRNA complement(160631..164320)
/gene="SIP3"
/locus_tag="YNL257C"
/product="Sip3p"
/transcript_id="NM_001183095.1"
/db_xref="GI:296147522"
/db_xref="GeneID:855464"
CDS complement(160631..164320)
/gene="SIP3"
/locus_tag="YNL257C"
/note="Protein that activates transcription through
interaction with DNA-bound Snf1p, C-terminal region has a
putative leucine zipper motif; potential Cdc28p substrate"
/codon_start=1
/product="Sip3p"
/protein_id="NP_014142.1"
/db_xref="GI:6324072"
/db_xref="SGD:S000005201"
/db_xref="GeneID:855464"
/translation="MSVHGRDPKKRQLRLISVAFKEASIDSPSFRASVNFFQTRVDAL
EDWIEKTVDFFDQKYKVSFEDFRRAKETLLSQLLPPPALLSNGFVSNQSFTPRLIDSF
NKDYYDFSMKLLQIVKGDDSSHSTALLELMTTAIEPYRNVRKNFDFYQGKYDSMLASY
QAIRISKTSLEPSSIKSDALQLFEVQKNYLKASLDLISAISAVKLSLDKFILESMKVL
KSRSIFITKDSGRKIDLSPCINEYLDNYAIWVENSIEGSKVLDSDISNAKKQAYRYTL
KRITPSSDTSDYNIRSIHSSKLLSKDTQVPPKSPEKSGWLYMKTQVGKPTREIWVRRW
CFLKNAVFGMFLLSPSKTYVEETDKFGVFLTNVRYDPEEDRKFCFEVKIFGNKVTEAH
DNMSKDITLVFQTSNYLDLKSWLIAFEATKKYVMSIQHDSLEYELAFKRFSPKFFEFA
SSTTTSIDQLITTFDKETESLYETLNCSISEYDILTLGEEKVFQFQMPTTPISTKMTQ
LAILSNFLTKGSWFPNAVLANIWGTTDWSEYTILPGKGKKPSSLLTIDGKRLPIRNST
IYPQYYSNELKVLDLQFKSLVFSPDQRLEKLPEELLLFKFEALWCPNKKQKFSATCFC
TKDYIYCYMNSMEFICLTKISLSEIVSVEADRSSKKTLKLYDASGLQMKAIVLFSDYK
LIASKLQYLLENKAIKNPNSNEEILVKFEQMEKESQEKKQEELYKIEQENSFDRKATS
VSKIIKSRVTFWEMSDDASTLLNRLKKLQTEYSITYNHEYEISSKGLAHILFGDKSNA
FPKCLFLARKDGEEHGKRFWYKNKDINGKSQLVRKIPFRLDMTGNFLNTGKYHRDKES
KMIFATQRIVKIVDNKYYEVDLDPFFVKVPFCHLLKLSIKFVITESYDVDNHLEIKLN
MTASSSSLHVLYKLEYIDSRTGKTIEKLSLAEIICQTWALKFAHSEFLLIRRVLRYYL
EKIGKHGKVIKAIKLCGILGVLSNKSEEPATEKNGNSKESESMQYDIRYSCTILFLVF
IKLMVYRVTNLTFVFFRILIGILLLCAEKFSRINRMMVVGLLASIMINILLSEKASVP
YWSIKRAEKLFHDRLGSDKFTMQRAIYISDSDLLSSQLSVPSNNPIFEKFSEDNFNKD
YQYSETRKQLAMRRNELLIELRILQDMEKQLVHDDYEKFLLEEVNKCSMVSIEMTDLW
FNDTQLQNYCSICNEELEKLRPPIT"
gene 164623..167097
/gene="FOL1"
/locus_tag="YNL256W"
/db_xref="GeneID:855465"
mRNA 164623..167097
/gene="FOL1"
/locus_tag="YNL256W"
/product="trifunctional dihydropteroate
synthetase/dihydrohydroxymethylpterin
pyrophosphokinase/dihydroneopterin aldolase FOL1"
/transcript_id="NM_001183094.1"
/db_xref="GI:296147523"
/db_xref="GeneID:855465"
CDS 164623..167097
/gene="FOL1"
/locus_tag="YNL256W"
/EC_number="4.1.2.25"
/EC_number="2.7.6.3"
/EC_number="2.5.1.15"
/note="Multifunctional enzyme of the folic acid
biosynthesis pathway, has dihydropteroate synthetase,
dihydro-6-hydroxymethylpterin pyrophosphokinase, and
dihydroneopterin aldolase activities"
/codon_start=1
/product="trifunctional dihydropteroate
synthetase/dihydrohydroxymethylpterin
pyrophosphokinase/dihydroneopterin aldolase FOL1"
/protein_id="NP_014143.2"
/db_xref="GI:37362687"
/db_xref="SGD:S000005200"
/db_xref="GeneID:855465"
/translation="MSKLFSTVNSARHSVPLGGMRDYVHIKKLEMNTVLGPDSWNQLM
PQKCLLSLDMGTDFSKSAATDDLKYSLNYAVISRDLTNFVSKKKNWGSVSNLAKSVSQ
FVMDKYSGVECLNLEVQADTTHIRSDHISCIIQQERGNPESQEFDVVRISELKMLTLI
GVFTFERLKKQYVTLDIKLPWPKKAELPPPVQSIIDNVVKFVEESNFKTVEALVESVS
AVIAHNEYFQKFPDSPLVVKVLKLNAITATEGVGVSCIREPREIAMVNIPYLSSIHES
SDIKFQLSSSQNTPIEGKNTWKRAFLAFGSNIGDRFKHIQMALQLLSREKTVKLRNIS
SIFESEPMYFKDQTPFMNGCVEVETLLTPSELLKLCKKIEYEELQRVKHFDNGPRTID
LDIVMFLNSAGEDIIVNEPDLNIPHPRMLERTFVLEPLCELISPVHLHPVTAEPIVDH
LKQLYDKQHDEDTLWKLVPLPYRSGVEPRFLKFKTATKLDEFTGETNRITVSPTYIMA
IFNATPDSFSDGGEHFADIESQLNDIIKLCKDALYLHESVIIDVGGCSTRPNSIQASE
EEEIRRSIPLIKAIRESTELPQDKVILSIDTYRSNVAKEAIKVGVDIINDISGGLFDS
NMFAVIAENPEICYILSHTRGDISTMNRLAHYENFALGDSIQQEFVHNTDIQQLDDLK
DKTVLIRNVGQEIGERYIKAIDNGVKRWQILIDPGLGFAKTWKQNLQIIRHIPILKNY
SFTMNSNNSQVYVNLRNMPVLLGPSRKKFIGHITKDVDAKQRDFATGAVVASCIGFGS
DMVRVHDVKNCSKSIKLADAIYKGLE"
gene complement(167329..167790)
/gene="GIS2"
/locus_tag="YNL255C"
/db_xref="GeneID:855466"
mRNA complement(167329..167790)
/gene="GIS2"
/locus_tag="YNL255C"
/product="Gis2p"
/transcript_id="NM_001183093.1"
/db_xref="GI:296147524"
/db_xref="GeneID:855466"
CDS complement(167329..167790)
/gene="GIS2"
/locus_tag="YNL255C"
/note="Translational activator for mRNAs with internal
ribosome entry sites; associates with polysomes and binds
to a specific subset of mRNAs; localizes to RNA processing
bodies (P bodies) and to stress granules; may have a role
in translation regulation under stress conditions;
ortholog of human ZNF9/CNBP, a gene involved in myotonic
dystrophy type 2"
/codon_start=1
/product="Gis2p"
/protein_id="NP_014144.1"
/db_xref="GI:6324074"
/db_xref="SGD:S000005199"
/db_xref="GeneID:855466"
/translation="MSQKACYVCGKIGHLAEDCDSERLCYNCNKPGHVQTDCTMPRTV
EFKQCYNCGETGHVRSECTVQRCFNCNQTGHISRECPEPKKTSRFSKVSCYKCGGPNH
MAKDCMKEDGISGLKCYTCGQAGHMSRDCQNDRLCYNCNETGHISKDCPKA"
gene complement(168043..169248)
/gene="RTC4"
/locus_tag="YNL254C"
/db_xref="GeneID:855467"
mRNA complement(168043..169248)
/gene="RTC4"
/locus_tag="YNL254C"
/product="Rtc4p"
/transcript_id="NM_001183092.1"
/db_xref="GI:296147525"
/db_xref="GeneID:855467"
CDS complement(168043..169248)
/gene="RTC4"
/locus_tag="YNL254C"
/note="hypothetical protein; null mutation suppresses
cdc13-1 temperature sensitivity; (GFP)-fusion protein
localizes to both the cytoplasm and the nucleus"
/codon_start=1
/product="Rtc4p"
/protein_id="NP_014145.1"
/db_xref="GI:6324075"
/db_xref="SGD:S000005198"
/db_xref="GeneID:855467"
/translation="MVGPGLGINRVRRKGVYSTKKGSGDNLLLMKRQGKHDIHDRESD
DLSGHDAFSPSKKRGKIDSITEDEIEVKKLSTVATFDKLSRSFPNSEVQAAKNAALRG
KEKEEEKVVSIPLIQNLKNEDIESIKCRNNNLLDGKKLLLEAELSAVEDNQIFSSSFP
EDKKLSLQSCLSSKEQIIKKLQVREEYMSKFKLPPMLFSDELLTEVEPFMPIVMDILE
GKISSVYYFEAKNAFKNSQKAYLSVDEFRKLNLNKFTAGFYGLKRQLRVGEEIAKRYK
RALTHNQPATLKWWGITDFCNYVLAPETLTSFCIYQLNLSNKSCSSKTPNKHPKQQLN
EKEYYYDPELRMLAYDLLEDTVEYGIIVADSDPIEQWEAAIEEDRLRELKLDVHNYSS
RRWRLDTHD"
rep_origin 169568..169805
/note="ARS1411;
ARS activated in late S phase"
/db_xref="SGD:S000077373"
gene 170018..171286
/gene="TEX1"
/locus_tag="YNL253W"
/db_xref="GeneID:855468"
mRNA 170018..171286
/gene="TEX1"
/locus_tag="YNL253W"
/product="Tex1p"
/transcript_id="NM_001183091.1"
/db_xref="GI:296147526"
/db_xref="GeneID:855468"
CDS 170018..171286
/gene="TEX1"
/locus_tag="YNL253W"
/note="Protein involved in mRNA export, component of the
transcription export (TREX) complex"
/codon_start=1
/product="Tex1p"
/protein_id="NP_014146.1"
/db_xref="GI:6324076"
/db_xref="SGD:S000005197"
/db_xref="GeneID:855468"
/translation="MSTIGAVDILNQKTITSEVAASVTSKYLQSTFSKGNTSHIEDKR
FIHVSSRSHSRFTSTPITPNEILSLKFHVSGSSMAYSRMDGSLTVWFIKDASFDKSVE
VYIPDCCGSDKLATDLSWNPTSLNQIAVVSNSSEISLLLINEKSLTASKLRTLSLGSK
TKVNTCLYDPLGNWLLAATKSEKIYLFDVKKDHSSVCSLNISDISQEDNDVVYSLAWS
NGGSHIFIGFKSGYLAILKAKHGILEVCTKIKAHTGPITEIKMDPWGRNFITGSIDGN
CYVWNMKSLCCELIINDLNSAVTTLDVCHLGKILGICTEDEMVYFYDLNSGNLLHSKS
LANYKTDPVLKFYPDKSWYIMSGKNDTLSNHFVKNEKNLITYWKDMFDNTMIEKRRKN
NGGGNNHNKRTSKNTDRIGKDRPSRFNSKK"
gene complement(171441..172286)
/gene="MRPL17"
/locus_tag="YNL252C"
/gene_synonym="MRPL30"
/db_xref="GeneID:855469"
mRNA complement(171441..172286)
/gene="MRPL17"
/locus_tag="YNL252C"
/gene_synonym="MRPL30"
/product="mitochondrial 54S ribosomal protein YmL17/YmL30"
/transcript_id="NM_001183090.1"
/db_xref="GI:296147527"
/db_xref="GeneID:855469"
CDS complement(171441..172286)
/gene="MRPL17"
/locus_tag="YNL252C"
/gene_synonym="MRPL30"
/note="Mitochondrial ribosomal protein of the large
subunit"
/codon_start=1
/product="mitochondrial 54S ribosomal protein YmL17/YmL30"
/protein_id="NP_014147.1"
/db_xref="GI:6324077"
/db_xref="SGD:S000005196"
/db_xref="GeneID:855469"
/translation="MKVNLMLKRGLATATATASSAPPKIKVGVLLSRIPIIKSELNEL
EKKYYEYQSELEKRLMWTFPAYFYFKKGTVAEHKFLSLQKGPISKKNGIWFPRGIPDI
KHGRERSTKQEVKLSDDSTVAFSNNQKEQSKDDVNRPVIPNDRITEADRSNDMKSLER
QLSRTLYLLVKDKSGTWKFPNFDLSDESKPLHVHAENELKLLSGDQIYTWSVSATPIG
VLQDERNRTAEFIVKSHILAGKFDLVASKNDAFEDFAWLTKGEISEYVPKDYFNKTEF
LLADN"
gene complement(172588..174315)
/gene="NRD1"
/locus_tag="YNL251C"
/db_xref="GeneID:855470"
mRNA complement(172588..174315)
/gene="NRD1"
/locus_tag="YNL251C"
/product="Nrd1p"
/transcript_id="NM_001183089.1"
/db_xref="GI:296147528"
/db_xref="GeneID:855470"
CDS complement(172588..174315)
/gene="NRD1"
/locus_tag="YNL251C"
/note="RNA-binding protein, subunit of Nrd1 complex
(Nrd1p-Nab3p-Sen1p); complex interacts with the exosome to
mediate 3' end formation of some mRNAs, snRNAs, snoRNAs,
and CUTs; interacts with the C-terminal domain of the RNA
polymerase II large subunit (Rpo21p), preferentially at
phosphorylated Ser5, to direct transcription termination
of non-polyadenylated transcripts; H3K4 trimethylation of
transcribed regions by Set1p enhances recruitment of Nrd1p
to those sites"
/codon_start=1
/product="Nrd1p"
/protein_id="NP_014148.1"
/db_xref="GI:6324078"
/db_xref="SGD:S000005195"
/db_xref="GeneID:855470"
/translation="MQQDDDFQNFVATLESFKDLKSGISGSRIKKLTTYALDHIDIES
KIISLIIDYSRLCPDSHKLGSLYIIDSIGRAYLDETRSNSNSSSNKPGTCAHAINTLG
EVIQELLSDAIAKSNQDHKEKIRMLLDIWDRSGLFQKSYLNAIRSKCFAMDISNNTAN
TASQQLSLDPKQRSKQILSNLKKSPPLNLNISLPTDLTSTDPAKQQAALFQVIAALQK
HFKTLPSHTSVGTVAPPQAHTITEYGSRRERERERERYNSRRNRSRSPPAPFSQPSTG
RKDRYPSVAQDQYSIGAPNTTFGTNNHHLYPDELNVSNNPHYRPKPVSYDSTLPPDHI
KVYSRTLFIGGVPLNMKEWDLANVLKPFAEVQSVILNNSRKHAFVKVYSRHEAENVLQ
NFNKDGALPLRTRWGVGFGPRDCCDYQHGYSIIPMHRLTDADKKWSVSAQWGGTSGQP
LVTGIVFEEPDIIVGEGVSSKAISQKMPTDSGRNGPRSGKPNKSGSISSISPVPYGNA
PLASPPPQQYVQPMMQQPYGYAPNQPLPSQGPAAAAPPVPQQQFDPTAQLNSLMNMLN
QQQQQQQQS"
gene 175410..179348
/gene="RAD50"
/locus_tag="YNL250W"
/db_xref="GeneID:855471"
mRNA 175410..179348
/gene="RAD50"
/locus_tag="YNL250W"
/product="Rad50p"
/transcript_id="NM_001183088.1"
/db_xref="GI:296147529"
/db_xref="GeneID:855471"
CDS 175410..179348
/gene="RAD50"
/locus_tag="YNL250W"
/EC_number="3.6.-.-"
/note="Subunit of MRX complex with Mre11p and Xrs2p;
complex is involved in processing double-strand DNA breaks
in vegetative cells, initiation of meiotic DSBs, telomere
maintenance, and nonhomologous end joining; forms nuclear
foci upon DNA replication stress"
/codon_start=1
/product="Rad50p"
/protein_id="NP_014149.1"
/db_xref="GI:6324079"
/db_xref="SGD:S000005194"
/db_xref="GeneID:855471"
/translation="MSAIYKLSIQGIRSFDSNDRETIEFGKPLTLIVGMNGSGKTTII
ECLKYATTGDLPPNSKGGVFIHDPKITGEKDIRAQVKLAFTSANGLNMIVTRNIQLLM
KKTTTTFKTLEGQLVAINNSGDRSTLSTRSLELDAQVPLYLGVPKAILEYVIFCHQED
SLWPLSEPSNLKKKFDEIFQAMKFTKALDNLKSIKKDMSVDIKLLKQSVEHLKLDKDR
SKAMKLNIHQLQTKIDQYNEEVSEIESQLNEITEKSDKLFKSNQDFQKILSKVENLKN
TKLSISDQVKRLSNSIDILDLSKPDLQNLLANFSKVLMDKNNQLRDLETDISSLKDRQ
SSLQSLSNSLIRRQGELEAGKETYEKNRNHLSSLKEAFQHKFQGLSNIENSDMAQVNH
EMSQFKAFISQDLTDTIDQFAKDIQLKETNLSDLIKSITVDSQNLEYNKKDRSKLIHD
SEELAEKLKSFKSLSTQDSLNHELENLKTYKEKLQSWESENIIPKLNQKIEEKNNEMI
ILENQIEKFQDRIMKTNQQADLYAKLGLIKKSINTKLDELQKITEKLQNDSRIRQVFP
LTQEFQRADLEMDFQKLFINMQKNIAINNKKMHELDRRYTNALYNLNTIEKDLQDNQK
SKEKVIQLLSENLPEDCTIDEYNDVLEETELSYKTALENLKMHQTTLEFNRKALEIAE
RDSCCYLCSRKFENESFKSKLLQELKTKTDANFEKTLKDTVQNEKEYLHSLRLLEKHI
ITLNSINEKIDNSQKCLEKAKEETKTSKSKLDELEVDSTKLKDEKELAESEIRPLIEK
FTYLEKELKDLENSSKTISEELSIYNTSEDGIQTVDELRDQQRKMNDSLRELRKTISD
LQMEKDEKVRENSRMINLIKEKELTVSEIESSLTQKQNIDDSIRSKRENINDIDSRVK
ELEARIISLKNKKDEAQSVLDKVKNERDIQVRNKQKTVADINRLIDRFQTIYNEVVDF
EAKGFDELQTTIKELELNKAQMLELKEQLDLKSNEVNEEKRKLADSNNEEKNLKQNLE
LIELKSQLQHIESEISRLDVQNAEAERDKYQEESLRLRTRFEKLSSENAGKLGEMKQL
QNQIDSLTHQLRTDYKDIEKNYHKEWVELQTRSFVTDDIDVYSKALDSAIMKYHGLKM
QDINRIIDELWKRTYSGTDIDTIKIRSDEVSSTVKGKSYNYRVVMYKQDVELDMRGRC
SAGQKVLASIIIRLALSETFGANCGVIALDEPTTNLDEENIESLAKSLHNIINMRRHQ
KNFQLIVITHDEKFLGHMNAAAFTDHFFKVKRDDRQKSQIEWVDINRVTY"
gene complement(179394..181022)
/gene="MPA43"
/locus_tag="YNL249C"
/db_xref="GeneID:855472"
mRNA complement(179394..181022)
/gene="MPA43"
/locus_tag="YNL249C"
/product="Mpa43p"
/transcript_id="NM_001183087.1"
/db_xref="GI:296147530"
/db_xref="GeneID:855472"
CDS complement(179394..181022)
/gene="MPA43"
/locus_tag="YNL249C"
/note="hypothetical protein; the authentic, non-tagged
protein is detected in highly purified mitochondria in
high-throughput studies"
/codon_start=1
/product="Mpa43p"
/protein_id="NP_014150.1"
/db_xref="GI:6324080"
/db_xref="SGD:S000005193"
/db_xref="GeneID:855472"
/translation="MNSSLQVGIGIDVGSSSARIGVYNYYNDALLEMAQEPVPYYQDS
SKKSWKFWQKSTEIIKALQKCLQKLNIREYEVKSCGVSATCSLAIFERDRTSNMLIPY
PNEDNVIFWMDSSAVNECQWLNMQCPQQLLDYLGGKFVPEMGVPKLKYFLDEYSHLRD
KHFHIFDLHQYIAYELSRLYEWNIEGLLGRENLNGIGNDGEVSGWSSSFYKNIINLPS
NVSIGTTSLVANKHISTTVVRSCIDSYASWFAVASPHLETSLFMIAGTSSCYMYGTTI
SDTRIPGVWGPFDTILDNRGDFSVYAAGQSCTGKLIEHLFESHPCARKILKDGADIYQ
VLEQTIRDIEKNNGLSIHILTKDMFFYGDYEGNRTPFADPRIKGSFIGESTDTSMLNL
TYKYICILEFLSFQTKLIIDTFQNENSNIHIKELRISGSQAKNERLLSLISLVNNGVA
IIKPKENVDMMGIKGAYVLAKSAKEKKQLADVITERDISNDSEKFESLAEYRLGNDSI
LLRKLLCVKYHIHLDMAKQQKRYHKLVDEVFQHL"
gene complement(181361..182608)
/gene="RPA49"
/locus_tag="YNL248C"
/db_xref="GeneID:855473"
mRNA complement(181361..182608)
/gene="RPA49"
/locus_tag="YNL248C"
/product="Rpa49p"
/transcript_id="NM_001183086.1"
/db_xref="GI:296147531"
/db_xref="GeneID:855473"
CDS complement(181361..182608)
/gene="RPA49"
/locus_tag="YNL248C"
/note="RNA polymerase I subunit A49"
/codon_start=1
/product="Rpa49p"
/protein_id="NP_014151.1"
/db_xref="GI:6324081"
/db_xref="SGD:S000005192"
/db_xref="GeneID:855473"
/translation="MSVKRSVSEIEIESVQDQPSVAVGSFFKGFRAPSDTTFDLYKKK
KSEKDEFVLHGENERLEYEGYTDSSSQASNQYVVGLFNPEKKSIQLYKAPVLVSKVVS
KSSKNLRGPKIKSKSDTRPSALRNALGEAFGTKKAKKAIADLERNRIDSDKLTDSAID
IVDSVRTASKDLPTRAQLDEITSNDRPTPLANIDATDVEQIYPIESIIPKKELQFIRV
SSILKEADKEKKLELFPYQNNSKYVAKKLDSLTQPSQMTKLQLLYYLSLLLGVYENRR
VNNKTKLLERLNSPPEILVDGILSRFTVIKPGQFGRSKDRSYFIDPQNEDKILCYILA
IIMHLDNFIVEITPLAHELNLKPSKVVSLFRVLGAIVKGATVAQAEAFGIPKSTAASY
KIATMKVPFKLPEMTRRGRGPRR"
gene 182875..185178
/locus_tag="YNL247W"
/db_xref="GeneID:855474"
mRNA 182875..185178
/locus_tag="YNL247W"
/product="cysteine--tRNA ligase"
/transcript_id="NM_001183085.1"
/db_xref="GI:296147532"
/db_xref="GeneID:855474"
CDS 182875..185178
/locus_tag="YNL247W"
/EC_number="6.1.1.16"
/note="Cysteinyl-tRNA synthetase; may interact with
ribosomes, based on co-purification experiments"
/codon_start=1
/product="cysteine--tRNA ligase"
/protein_id="NP_014152.1"
/db_xref="GI:6324082"
/db_xref="SGD:S000005191"
/db_xref="GeneID:855474"
/translation="MNIFIKALRRYTIMSTPKIVQPKWKVPTPQAKETVLKLYNSLTR
SKVEFIPQSGNRGVTWYSCGPTVYDASHMGHARNYVSIDINRRIIQDYFGYDVQFVQN
VTDIDDKIILRARQNYLFDNFVKENDTKFNATVVDKVKTALFQYINKNFTIQGSEIKT
IEEFETWLSNADTETLKLENPKFPMHVTAVQNAIESITKGDSMDAEVAFEKVKDVTVP
LLDKELGSTISNPEIFRQLPAYWEQKFNDDMLSLNVLPPTVTTRVSEYVPEIIDFVQK
IIDNGYAYATSDGSVYFDTLKFDKSPNHDYAKCQPWNKGQLDLINDGEGSLSNFADNG
KKSNNDFALWKASKAGEPEWESPWGKGRPGWHIECSVMASDILGSNIDIHSGGIDLAF
PHHDNELAQSEARFDNQQWINYFLHTGHLHIEGQKMSKSLKNFITIQEALKKFSPRQL
RLAFASVQWNNQLDFKESLIHEVKSFENSMNNFFKTIRALKNDAASAGHISKKFSPLE
KELLADFVESESKVHSAFCDNLSTPVALKTLSELVTKSNTYITTAGAALKIEPLIAIC
SYITKILRIIGFPSRPDNLGWAAQAGSNDGSLGSLEDTVMPYVKCLSTFRDDVRSLAI
KKAEPKEFLQLTDKIRNEDLLNLNVALDDRNGQSALIKFLTNDEKLEIVKLNEEKHAN
ELAKKQKKLEQQKLREQKENERKQKAQIKPQDMFKDVTLYSAWDEQGLPTKDKDGNDI
TKSMTKKLKKQWEQQKKLHEEYFGEDK"
gene 185460..186349
/gene="VPS75"
/locus_tag="YNL246W"
/db_xref="GeneID:855475"
mRNA join(185460..185491,185587..186349)
/gene="VPS75"
/locus_tag="YNL246W"
/product="Vps75p"
/transcript_id="NM_001183084.1"
/db_xref="GI:296147533"
/db_xref="GeneID:855475"
CDS join(185460..185491,185587..186349)
/gene="VPS75"
/locus_tag="YNL246W"
/note="NAP family histone chaperone; binds to histones and
Rtt109p, stimulating histone acetyltransferase activity;
possesses nucleosome assembly activity in vitro; proposed
role in vacuolar protein sorting and in double-strand
break repair; protein abundance increases in response to
DNA replication stress"
/codon_start=1
/product="Vps75p"
/protein_id="NP_014153.1"
/db_xref="GI:6324083"
/db_xref="SGD:S000005190"
/db_xref="GeneID:855475"
/translation="MMSDQENENEHAKAFLGLAKCEEEVDAIEREVELYRLNKMKPVY
EKRDAYIDEIAEFWKIVLSQHVSFANYIRASDFKYIDTIDKIKVEWLALESEMYDTRD
FSITFHFHGIEGDFKEQQVTKVFQIKKGKDDQEDGILTSEPVPIEWPQSYDSINPDLI
KDKRSPEGKKKYRQGMKTIFGWFRWTGLKPGKEFPHGDSLASLFSEEIYPFCVKYYAE
AQRDLEDEEGESGLSADGDSEDDDGSLGEVDLPLSDEEPSSKKRKV"
gene complement(186346..186885)
/gene="CWC25"
/locus_tag="YNL245C"
/db_xref="GeneID:855476"
mRNA complement(186346..186885)
/gene="CWC25"
/locus_tag="YNL245C"
/product="Cwc25p"
/transcript_id="NM_001183083.1"
/db_xref="GI:296147534"
/db_xref="GeneID:855476"
CDS complement(186346..186885)
/gene="CWC25"
/locus_tag="YNL245C"
/note="Splicing factor required for the first step of
pre-mRNA splicing; binding to the spliceosome requires
Prp2p and Yju2p; heat-stable protein; has similarity to S.
pombe Cwf25p"
/codon_start=1
/product="Cwc25p"
/protein_id="NP_014154.1"
/db_xref="GI:6324084"
/db_xref="SGD:S000005189"
/db_xref="GeneID:855476"
/translation="MGSGDLNLLKSWNPKLMKNRKKVWETEQDLITEQQKLNTRLKEI
EKERELNELLNESSKDKPETLKNDLALKKSGLEWMYQDAKLSDEKEDYLLGKKKLDSS
ILNQPATPPVRAATTISASGAATSISSQKKKSKLLKDDPMSKFKVTKQQRRTPDSTKK
RAMSQRGKPLSKPAPDLDY"
gene complement(187170..187496)
/gene="SUI1"
/locus_tag="YNL244C"
/gene_synonym="MOF2; RFR1"
/db_xref="GeneID:855477"
mRNA complement(187170..187496)
/gene="SUI1"
/locus_tag="YNL244C"
/gene_synonym="MOF2; RFR1"
/product="Sui1p"
/transcript_id="NM_001183082.1"
/db_xref="GI:296147535"
/db_xref="GeneID:855477"
CDS complement(187170..187496)
/gene="SUI1"
/locus_tag="YNL244C"
/gene_synonym="MOF2; RFR1"
/note="Translation initiation factor eIF1; component of a
complex involved in recognition of the initiator codon;
modulates translation accuracy at the initiation phase"
/codon_start=1
/product="Sui1p"
/protein_id="NP_014155.1"
/db_xref="GI:6324085"
/db_xref="SGD:S000005188"
/db_xref="GeneID:855477"
/translation="MSIENLKSFDPFADTGDDETATSNYIHIRIQQRNGRKTLTTVQG
VPEEYDLKRILKVLKKDFACNGNIVKDPEMGEIIQLQGDQRAKVCEFMISQLGLQKKN
IKIHGF"
gene 188051..190957
/gene="SLA2"
/locus_tag="YNL243W"
/gene_synonym="END4; MOP2"
/db_xref="GeneID:855478"
mRNA 188051..190957
/gene="SLA2"
/locus_tag="YNL243W"
/gene_synonym="END4; MOP2"
/product="Sla2p"
/transcript_id="NM_001183081.2"
/db_xref="GI:330443693"
/db_xref="GeneID:855478"
CDS 188051..190957
/gene="SLA2"
/locus_tag="YNL243W"
/gene_synonym="END4; MOP2"
/note="Adaptor protein that links actin to clathrin and
endocytosis; involved in membrane cytoskeleton assembly
and cell polarization; present in the actin cortical patch
of the emerging bud tip; dimer in vivo"
/codon_start=1
/product="Sla2p"
/protein_id="NP_014156.2"
/db_xref="GI:330443694"
/db_xref="SGD:S000005187"
/db_xref="GeneID:855478"
/translation="MSRIDSDLQKALKKACSVEETAPKRKHVRACIVYTWDHQSSKAV
FTTLKTLPLANDEVQLFKMLIVLHKIIQEGHPSALAEAIRDRDWIRSLGRVHSGGSSY
SKLIREYVRYLVLKLDFHAHHRGFNNGTFEYEEYVSLVSVSDPDEGYETILDLMSLQD
SLDEFSQIIFASIQSERRNTECKISALIPLIAESYGIYKFITSMLRAMHRQLNDAEGD
AALQPLKERYELQHARLFEFYADCSSVKYLTTLVTIPKLPVDAPDVFLINDVDESKEI
KFKKREPSVTPARTPARTPTPTPPVVAEPAISPRPVSQRTTSTPTGYLQTMPTGATTG
MMIPTATGAANAIFPQATAQMQPDFWANQQAQFANEQNRLEQERVQQLQQQQAQQELF
QQQLQKAQQDMMNMQLQQQNQHQNDLIALTNQYEKDQALLQQYDQRVQQLESEITTMD
STASKQLANKDEQLTALQDQLDVWERKYESLAKLYSQLRQEHLNLLPRFKKLQLKVNS
AQESIQKKEQLEHKLKQKDLQMAELVKDRDRARLELERSINNAEADSAAATAAAETMT
QDKMNPILDAILESGINTIQESVYNLDSPLSWSGPLTPPTFLLSLLESTSENATEFAT
SFNNLIVDGLAHGDQTEVIHCVSDFSTSMATLVTNSKAYAVTTLPQEQSDQILTLVKR
CAREAQYFFEDLMSENLNQVGDEEKTDIVINANVDMQEKLQELSLAIEPLLNIQSVKS
NKETNPHSELVATADKIVKSSEHLRVDVPKPLLSLALMIIDAVVALVKAAIQCQNEIA
TTTSIPLNQFYLKNSRWTEGLISAAKAVAGATNVLITTASKLITSEDNENTSPEQFIV
ASKEVAASTIQLVAASRVKTSIHSKAQDKLEHCSKDVTDACRSLGNHVMGMIEDDHST
SQQQQPLDFTSEHTLKTAEMEQQVEILKLEQSLSNARKRLGEIRRHAYYNQDDD"
gene 191324..196102
/gene="ATG2"
/locus_tag="YNL242W"
/gene_synonym="APG2; AUT8; SPO72"
/db_xref="GeneID:855479"
mRNA 191324..196102
/gene="ATG2"
/locus_tag="YNL242W"
/gene_synonym="APG2; AUT8; SPO72"
/product="Atg2p"
/transcript_id="NM_001183080.1"
/db_xref="GI:296147537"
/db_xref="GeneID:855479"
CDS 191324..196102
/gene="ATG2"
/locus_tag="YNL242W"
/gene_synonym="APG2; AUT8; SPO72"
/note="Peripheral membrane protein required for autophagic
vesicle formation; also required for vesicle formation
during pexophagy and the cytoplasm-to-vaucole targeting
(Cvt) pathway; involved in Atg9p cycling between the
phagophore assembly site and mitochondria; forms
cytoplasmic foci upon DNA replication stress"
/codon_start=1
/product="Atg2p"
/protein_id="NP_014157.1"
/db_xref="GI:6324087"
/db_xref="SGD:S000005186"
/db_xref="GeneID:855479"
/translation="MAFWLPQNIQKRLLLYVLQQISLFSNIDLSNLDVSIGSKSHFSF
HDVNLSLDDLNIPNVQINEGIVDELVLKLTVSGGVEIDGSGLRFIMTPLYSSGSQELH
SDFLVKSIQDLTNSMLQFSDPLTTYNRYKEDDISSSDSSSDLNSNIEASKPAANGSYT
LQNMRNKALNVALAKLKIALKDVTIRFIVNDRDPSDNIVEVHLESIQLITTDANLRHI
NIENITISSIQKQAVPDSPVHPFNNDDLSQSVYLSKMEATSLYMSAMEEQSNEDPSEP
QVTQEEQENDKCKESLMEINNLNIAFKGLSSVNDLRMSNIVIDIQDVHLAIHKIVEIK
NSTLKNIIDIIVTHLDANESFSCQDSQSPSPDKQEPSALSSVDIKCIYLNLGQDITVI
LKSFKLEQKENNSLAFSLGSFYSNSSPLTISHKTKPLLTGEQTPQSIALNMGDELDII
ISHDGIAHFFKIFQFVSKCMSFYQNKSKGMMPQIASDTKRTVQLTSKAVKLSLKFPYF
LLCFQVSPFIYDSNRELYIELVDVFKKLPSRCTKILTMSSITISNLQSPLQLGSYDDT
LKEALIYSSVHAIIKEVIFNEEYSGIVQLVEDISAFGKLFTDSKNSECTGKSKSKRGS
FLQRSVRVLNSSRFVYKQSLSANFSLKIDSMKLKVSEIIGPQFGSVEALLSNNFFAIT
DDSQIVYFTKNLKVERKTPSLLEPQEIMSVVLNKAVNEPVLYVHRRANGKLKVIFNNI
RIHYYARWLEILKKNIGPDNASSKDEPVSQKLSKKQPTSGFPWELKCLDCSLILHPFR
LKSVMVIVLDNLTTGGSSFIPQAKLLSKANTLFLIDDYQNFKIQKDKNWPSLINFYAG
QGFSAIGKIDTLNFLINKSDGALLLDCKIEQVGLSLCADSFQTFCQLCIDLKYPQTFP
DEEKFRTQLKNPIDVFKDIDCDLFNSAFIRENNHQNDYDSVHLVDSFLDKTHEFNNGA
RSKLSSQGSYEMDSSSGTATGGILLPHESYLDSAQPKEEDTPPIASKEQERDVDIRGS
IDVEKVVIKLFDGYDWKYTRKFIANTVEKLDKELSKAEASSSKSNVPQSEANIFDSIY
ISANKNNVTDLRRNLDGEIQGVQNSFSDVSKVNLRPSKHYKALIQLNKVHVNLKNYRV
DEPDESNSDNSTDVLNRCVVSIYEFEIIDNVPTSTWNKFVTLLKHEPWPHSSPMFLLD
LEFIRPIDFLQAVELVMQLNVAPLRLHVDQDTLEFLIRFLGFKDKRFELIDEYPDIVF
IQKFSTNSIKLRLDYKPKKVDYAGLRSGQTSELMNFFTLDGSKIILKSVVLYGLNGFD
ELNNKLKAIWTPDITKKQLPGVLEGLAPVRSFMAIGSGVKTLVTVLMSEYRQEGHLGR
SLKKGGNVFLKTTTGDFVKLGVKLTSGTQAILENTEELFGGVGSNGRVYDASKFGSAD
GADSDTAAVLDLDTLFEEDQLVGSKYSRIRDHEPTAVVIDMSSPGDHNEPTIVSLYAD
QPLDLPTGLKEAYSSLEKHMHIAYDAVWRAKGQMKDDKRGGPSAAAVYVARAAPVAII
RPLIGATEAVSKTLQGIANQVDKTHNEQINDKYKSNRTDS"
rep_origin 196057..196292
/note="ARS1412;
ARS activated in late S phase"
/db_xref="SGD:S000077374"
gene complement(196426..197943)
/gene="ZWF1"
/locus_tag="YNL241C"
/gene_synonym="MET19; POS10"
/db_xref="GeneID:855480"
mRNA complement(196426..197943)
/gene="ZWF1"
/locus_tag="YNL241C"
/gene_synonym="MET19; POS10"
/product="glucose-6-phosphate dehydrogenase"
/transcript_id="NM_001183079.1"
/db_xref="GI:296147538"
/db_xref="GeneID:855480"
CDS complement(196426..197943)
/gene="ZWF1"
/locus_tag="YNL241C"
/gene_synonym="MET19; POS10"
/EC_number="1.1.1.49"
/note="Glucose-6-phosphate dehydrogenase (G6PD); catalyzes
the first step of the pentose phosphate pathway; involved
in adapting to oxidatve stress; homolog of the human G6PD
which is deficient in patients with hemolytic anemia;
protein abundance increases in response to DNA replication
stress"
/codon_start=1
/product="glucose-6-phosphate dehydrogenase"
/protein_id="NP_014158.1"
/db_xref="GI:6324088"
/db_xref="SGD:S000005185"
/db_xref="GeneID:855480"
/translation="MSEGPVKFEKNTVISVFGASGDLAKKKTFPALFGLFREGYLDPS
TKIFGYARSKLSMEEDLKSRVLPHLKKPHGEADDSKVEQFFKMVSYISGNYDTDEGFD
ELRTQIEKFEKSANVDVPHRLFYLALPPSVFLTVAKQIKSRVYAENGITRVIVEKPFG
HDLASARELQKNLGPLFKEEELYRIDHYLGKELVKNLLVLRFGNQFLNASWNRDNIQS
VQISFKERFGTEGRGGYFDSIGIIRDVMQNHLLQIMTLLTMERPVSFDPESIRDEKVK
VLKAVAPIDTDDVLLGQYGKSEDGSKPAYVDDDTVDKDSKCVTFAAMTFNIENERWEG
VPIMMRAGKALNESKVEIRLQYKAVASGVFKDIPNNELVIRVQPDAAVYLKFNAKTPG
LSNATQVTDLNLTYASRYQDFWIPEAYEVLIRDALLGDHSNFVRDDELDISWGIFTPL
LKHIERPDGPTPEIYPYGSRGPKGLKEYMQKHKYVMPEKHPYAWPVTKPEDTKDN"
gene complement(198502..199977)
/gene="NAR1"
/locus_tag="YNL240C"
/db_xref="GeneID:855481"
mRNA complement(198502..199977)
/gene="NAR1"
/locus_tag="YNL240C"
/product="Nar1p"
/transcript_id="NM_001183078.1"
/db_xref="GI:296147539"
/db_xref="GeneID:855481"
CDS complement(198502..199977)
/gene="NAR1"
/locus_tag="YNL240C"
/note="Component of the cytosolic iron-sulfur (FeS)
protein assembly machinery, required for maturation of
cytosolic and nuclear FeS proteins and for normal
resistance to oxidative stress; homologous to human Narf"
/codon_start=1
/product="Nar1p"
/protein_id="NP_014159.1"
/db_xref="GI:6324089"
/db_xref="SGD:S000005184"
/db_xref="GeneID:855481"
/translation="MSALLSESDLNDFISPALACVKPTQVSGGKKDNVNMNGEYEVST
EPDQLEKVSITLSDCLACSGCITSSEEILLSSQSHSVFLKNWGKLSQQQDKFLVVSVS
PQCRLSLAQYYGLTLEAADLCLMNFFQKHFQCKYMVGTEMGRIISISKTVEKIIAHKK
QKENTGADRKPLLSAVCPGFLIYTEKTKPQLVPMLLNVKSPQQITGSLIRATFESLAI
ARESFYHLSLMPCFDKKLEASRPESLDDGIDCVITPREIVTMLQELNLDFKSFLTEDT
SLYGRLSPPGWDPRVHWASNLGGTCGGYAYQYVTAVQRLHPGSQMIVLEGRNSDIVEY
RLLHDDRIIAAASELSGFRNIQNLVRKLTSGSGSERKRNITALRKRRTGPKANSREMA
AATAATADPYHSDYIEVNACPGACMNGGGLLNGEQNSLKRKQLVQTLNKRHGEELAMV
DPLTLGPKLEEAAARPLSLEYVFAPVKQAVEKDLVSVGSTW"
gene 200569..201933
/gene="LAP3"
/locus_tag="YNL239W"
/gene_synonym="BLH1; GAL6; YCP1"
/db_xref="GeneID:855482"
mRNA 200569..201933
/gene="LAP3"
/locus_tag="YNL239W"
/gene_synonym="BLH1; GAL6; YCP1"
/product="Lap3p"
/transcript_id="NM_001183077.1"
/db_xref="GI:296147540"
/db_xref="GeneID:855482"
CDS 200569..201933
/gene="LAP3"
/locus_tag="YNL239W"
/gene_synonym="BLH1; GAL6; YCP1"
/EC_number="3.4.22.40"
/note="Cysteine aminopeptidase with
homocysteine-thiolactonase activity; protects cells
against homocysteine toxicity; has bleomycin hydrolase
activity in vitro; transcription is regulated by galactose
via Gal4p; orthologous to human BLMH"
/codon_start=1
/product="Lap3p"
/protein_id="NP_014160.2"
/db_xref="GI:27808714"
/db_xref="SGD:S000005183"
/db_xref="GeneID:855482"
/translation="MSSSIDISKINSWNKEFQSDLTHQLATTVLKNYNADDALLNKTR
LQKQDNRVFNTVVSTDSTPVTNQKSSGRCWLFAATNQLRLNVLSELNLKEFELSQAYL
FFYDKLEKANYFLDQIVSSADQDIDSRLVQYLLAAPTEDGGQYSMFLNLVKKYGLIPK
DLYGDLPYSTTASRKWNSLLTTKLREFAETLRTALKERSADDSIIVTLREQMQREIFR
LMSLFMDIPPVQPNEQFTWEYVDKDKKIHTIKSTPLEFASKYAKLDPSTPVSLINDPR
HPYGKLIKIDRLGNVLGGDAVIYLNVDNETLSKLVVKRLQNNKAVFFGSHTPKFMDKK
TGVMDIELWNYPAIGYNLPQQKASRIRYHESLMTHAMLITGCHVDETSKLPLRYRVEN
SWGKDSGKDGLYVMTQKYFEEYCFQIVVDINELPKELASKFTSGKEEPIVLPIWDPMG
ALAK"
gene 202428..204872
/gene="KEX2"
/locus_tag="YNL238W"
/gene_synonym="QDS1; SRB1; VMA45"
/db_xref="GeneID:855483"
mRNA 202428..204872
/gene="KEX2"
/locus_tag="YNL238W"
/gene_synonym="QDS1; SRB1; VMA45"
/product="Kex2p"
/transcript_id="NM_001183076.1"
/db_xref="GI:296147541"
/db_xref="GeneID:855483"
CDS 202428..204872
/gene="KEX2"
/locus_tag="YNL238W"
/gene_synonym="QDS1; SRB1; VMA45"
/EC_number="3.4.21.61"
/note="Subtilisin-like protease (proprotein convertase), a
calcium-dependent serine protease involved in the
activation of proproteins of the secretory pathway"
/codon_start=1
/product="Kex2p"
/protein_id="NP_014161.1"
/db_xref="GI:6324091"
/db_xref="SGD:S000005182"
/db_xref="GeneID:855483"
/translation="MKVRKYITLCFWWAFSTSALVSSQQIPLKDHTSRQYFAVESNET
LSRLEEMHPNWKYEHDVRGLPNHYVFSKELLKLGKRSSLEELQGDNNDHILSVHDLFP
RNDLFKRLPVPAPPMDSSLLPVKEAEDKLSINDPLFERQWHLVNPSFPGSDINVLDLW
YNNITGAGVVAAIVDDGLDYENEDLKDNFCAEGSWDFNDNTNLPKPRLSDDYHGTRCA
GEIAAKKGNNFCGVGVGYNAKISGIRILSGDITTEDEAASLIYGLDVNDIYSCSWGPA
DDGRHLQGPSDLVKKALVKGVTEGRDSKGAIYVFASGNGGTRGDNCNYDGYTNSIYSI
TIGAIDHKDLHPPYSEGCSAVMAVTYSSGSGEYIHSSDINGRCSNSHGGTSAAAPLAA
GVYTLLLEANPNLTWRDVQYLSILSAVGLEKNADGDWRDSAMGKKYSHRYGFGKIDAH
KLIEMSKTWENVNAQTWFYLPTLYVSQSTNSTEETLESVITISEKSLQDANFKRIEHV
TVTVDIDTEIRGTTTVDLISPAGIISNLGVVRPRDVSSEGFKDWTFMSVAHWGENGVG
DWKIKVKTTENGHRIDFHSWRLKLFGESIDSSKTETFVFGNDKEEVEPAATESTVSQY
SASSTSISISATSTSSISIGVETSAIPQTTTASTDPDSDPNTPKKLSSPRQAMHYFLT
IFLIGATFLVLYFMFFMKSRRRIRRSRAETYEFDIIDTDSEYDSTLDNGTSGITEPEE
VEDFDFDLSDEDHLASLSSSENGDAEHTIDSVLTNENPFSDPIKQKFPNDANAESASN
KLQELQPDVPPSSGRS"
gene 205188..206567
/gene="YTP1"
/locus_tag="YNL237W"
/db_xref="GeneID:855484"
mRNA 205188..206567
/gene="YTP1"
/locus_tag="YNL237W"
/product="Ytp1p"
/transcript_id="NM_001183075.1"
/db_xref="GI:296147542"
/db_xref="GeneID:855484"
CDS 205188..206567
/gene="YTP1"
/locus_tag="YNL237W"
/note="Probable type-III integral membrane hypothetical
protein, has regions of similarity to mitochondrial
electron transport proteins"
/codon_start=1
/product="Ytp1p"
/protein_id="NP_014162.1"
/db_xref="GI:6324092"
/db_xref="SGD:S000005181"
/db_xref="GeneID:855484"
/translation="MTAANKNIVFGFSRSISAILLICFFFEKVCGDMEHDMGMDDTSG
YTRPEIVQAGSKSFHWLCTLGFLLLLPSVVTCLSFAGRIYSATLLQCTCAVYAFLEAA
VLRFQDNDGVENRTSRGTAWFLVGLTWITLFFGGLAGGTGFLVKSKRLQTFISNAGEK
RLSYIHRGLSFLTVLTGWVKVCLAPVALFGFCREAHTGQCIAHGIMGSAFVLYGFIYV
LVLVIPWIRSAQTSYSQDYVDSWVMCIWGVVNTFTEHRWGREGWSVHDYQHTFMGIIW
WTGGILGIFLSRNGRRTFVPSLIIIFTGWAMSEHAQHLIISTKVHNMFGLVLMCGGAL
RIIEISFLLRDKRTLDKIHSFQYLAPFCLVCSGLLFMGANEEQLILVLRLGGDHSAYV
LIIVSGAFLVYFWMIACLEFYLYLLEKGKQGFLPKSYELEEENNNVSFELDNISNEDV
DEDTTPFNV"
gene 206930..209854
/gene="SIN4"
/locus_tag="YNL236W"
/gene_synonym="BEL2; GAL22; MED16; RYE1; SDI3; SSF5; SSN4;
TSF3"
/db_xref="GeneID:855485"
mRNA 206930..209854
/gene="SIN4"
/locus_tag="YNL236W"
/gene_synonym="BEL2; GAL22; MED16; RYE1; SDI3; SSF5; SSN4;
TSF3"
/product="Sin4p"
/transcript_id="NM_001183074.1"
/db_xref="GI:296147543"
/db_xref="GeneID:855485"
CDS 206930..209854
/gene="SIN4"
/locus_tag="YNL236W"
/gene_synonym="BEL2; GAL22; MED16; RYE1; SDI3; SSF5; SSN4;
TSF3"
/note="Subunit of the RNA polymerase II mediator complex;
associates with core polymerase subunits to form the RNA
polymerase II holoenzyme; contributes to both postive and
negative transcriptional regulation; dispensible for basal
transcription"
/codon_start=1
/product="Sin4p"
/protein_id="NP_014163.1"
/db_xref="GI:6324093"
/db_xref="SGD:S000005180"
/db_xref="GeneID:855485"
/translation="MMLGEHLMSWSKTGIIAYSDSQSSNANICLTFLESINGINWRFH
TPQKYVLHPQLHEVQYQESSSTLSTHSTTTSVNGSTTAGVGSTPNFGGNSNKSPPQFF
YNISSIHWNNWFSLPGDMLAVCDELGNMTMLITGQRPDRATTYEKLTMVFQDNVYKIY
NHVMPLKPVDKLKPMNIERKQTRKEYNTSILEFRWLTSSKSVIVSQFCAFDSSSNTYR
SRAQQVPPYGVYHPPFIKYACLAIRKNGQIDFWYQFSNSKDHKKITLQLLDTSNQRFK
DLQWLEFARITPMNDDQCMLITTYSKLSKNISFYKLHVNWNLNATKPNVLNDPSLKIQ
FILSTTLDPTDDEGHVLKLENLHVVSKSSIEKDPSPEILVLYNVCDTSKSLVKRYRLA
PTQLSAEYLVILKPDLNIDRNNSTNQIFQSRRYNLRRHSDIVLDKKVTLITSEMFDAF
VSFYFEDGTIESYNQNDWKLETERLISQSQLGKFKNIIASPLSAGFNYGKLPLPPSVE
WMKVSPSMCGVIVKQYNKKWPQFYAAVQKNYADPEKDSINATALAFGYVKSLHKQISA
EDLTIAAKTHILRISFLDRKRAKEFITTLLKSLYSFFNISPDAPKEIMDKIITSRPLQ
KIMLLQLELGSCFSQENIEEMARVILYLKNVLFAFNGVARNFHFAIEQISNNSNQQQN
PKLFQTIFSKQDLIHSLIPVAKWFVKFITYLTQEILILINDPTNKEYTLVHGIFGAKM
SRTLILSILNEIKKVTQIVAKFPETSYPILNESSTFLKLVLSESPVDFEKFETFLVDV
NNKFIALCEQQPSQEREFSLLVKAEIPPEYAKVGDFLLQYANNAVISHANAAAVYFAD
TSGLKISNSEFFNPEIFHLLQPLEEGLIIDTDKLPIKNRTSKSFSKLLYDDVTCDKLS
VSEISDGKLKRCSRCGSVTRAGNIISSDKTIVPTSIQTKRWPTMYTRLCICSGMLFEM
DG"
gene 210233..211513
/locus_tag="YNL234W"
/db_xref="GeneID:855487"
mRNA 210233..211513
/locus_tag="YNL234W"
/product="hypothetical protein"
/transcript_id="NM_001183072.1"
/db_xref="GI:296147544"
/db_xref="GeneID:855487"
CDS 210233..211513
/locus_tag="YNL234W"
/note="hypothetical protein with similarity to globins;
has a functional heme-binding domain; mutant has
aneuploidy tolerance; transcription induced by stress
conditions; may be involved in glucose signaling or
metabolism; regulated by Rgt1"
/codon_start=1
/product="hypothetical protein"
/protein_id="NP_014165.1"
/db_xref="GI:6324095"
/db_xref="SGD:S000005178"
/db_xref="GeneID:855487"
/translation="MTGEKILHSQLLTNSDMSSGNVHHTKPMMYNVTLPSYNSSSIGP
VDNLKINERPGSHDHSMRSEMSSKNSGSDFMPQSISRSEGSVYQVKIDRGDSPNTEGF
DFKVNARDLLLLRMSWDILLREYLTPKELKVFQALLYSNKHITSTERPYLNTAPDGMI
SKTIDPTARPRKTKQRDNDNKVDTALFCSQFYDNLIAMDPLLEEYFPSLKHQAVSFCK
VLDSAIDNLENVHVLDDYIVKLGKRHSRILGIKTVGFEVMGKAFMTTLQDRFGSFLTL
ELKNLWGQLYSYLANCMITAGKDPMEKIQPDFSYNGDSVVLNFSIPKLAMHDISTVNK
LQMVKTKNATIPHNITQVPTNKIPTEILLDNSSTPIKSDRESTPPISPKGSGSTKPSI
GSSTVVESNTKKNNYDEKIHLLQKTAQQKNCSIM"
gene 211922..214600
/gene="BNI4"
/locus_tag="YNL233W"
/db_xref="GeneID:855488"
mRNA 211922..214600
/gene="BNI4"
/locus_tag="YNL233W"
/product="Bni4p"
/transcript_id="NM_001183071.1"
/db_xref="GI:296147545"
/db_xref="GeneID:855488"
CDS 211922..214600
/gene="BNI4"
/locus_tag="YNL233W"
/note="Targeting subunit for Glc7p protein phosphatase,
localized to the bud neck, required for localization of
chitin synthase III to the bud neck via interaction with
the chitin synthase III regulatory subunit Skt5p"
/codon_start=1
/product="Bni4p"
/protein_id="NP_014166.1"
/db_xref="GI:6324096"
/db_xref="SGD:S000005177"
/db_xref="GeneID:855488"
/translation="MSDSISDSKSSELLNSTFYSSTSINTLDHARTFRNSLILKEISD
QSLNSSIKPCESVLDRDVESSVLQRSFGESNARDSEVQTVNMTTSPSLSALADILNER
SKYADQKTRKAQNIESSIIEEEEEAEEQNNSINYHEDITGSRLSVREEANENLAMTSP
NLIDIDGSNSIQVAPLSLPSFEEPDFLSTPRVKPDSQGPRSKVSTRRTILERDNNLPV
KREENTIINSETESTTHSAPFLKEDPKPSPPSSKLYNPKVRLNKAEARKYTDSSAQRT
TSAGSVLEDTSMHKKKKSIFSFLKKKEPKPVIGNNSVTNEKNKMSSSSTFSMNIQTSL
KTPEKLKKKSHSSSSIFNSFLKGKIETSDSPRKEPMRQKKRTPKSKDKKQDTEQIIDA
ASVLSTESPLLRKNHDDTPVKIDHVTRSIDQRKPTPLNMDLILGGDKQINTPLQEHVR
EDDDAKNDLQLPTKDNFLSLDYEAPSPAFSKHDTGEVLFPKFLDNHEVDSIVSLERTR
STKSNKRSSMNSQRRSLTDTLSIKAQSEGMFITEASSVVLSTPDLTKSPASSILKNGR
FEYSDNFSREHSYEGTTNEDFLDIKDDSGPLKKDDIFLESIEQKFDQLVMASDEEKTE
VERDVPKPREEPLKKDSERQSVFADDDNELISDIMEFASFINFGDDDLNLDLDLGDTT
ASYATETPEPVGNDEVNRSGTFDTRNNKEDSYKERETQSYSAAGATTYGDERQGQLHT
FEQDGSEINDNEFENEDFNKHIEQPIEVTPRNNAYLPEFEPNRPVSMSFKGLKAPRMN
TSFIDSMTPDSPVKSDLTSLGEVYVNSNNDQGVRFSSQIILYDTYGEFEYDRHPEIST
CNQLTPQLAQMIKLELNELKSAMEVHDDSRCYTHFY"
gene 214923..215801
/gene="CSL4"
/locus_tag="YNL232W"
/gene_synonym="SKI4"
/db_xref="GeneID:855489"
mRNA 214923..215801
/gene="CSL4"
/locus_tag="YNL232W"
/gene_synonym="SKI4"
/product="Csl4p"
/transcript_id="NM_001183070.1"
/db_xref="GI:296147546"
/db_xref="GeneID:855489"
CDS 214923..215801
/gene="CSL4"
/locus_tag="YNL232W"
/gene_synonym="SKI4"
/EC_number="3.1.13.-"
/note="Exosome non-catalytic core component; involved in
3'-5' RNA processing and degradation in both the nucleus
and the cytoplasm; predicted to contain an S1 RNA binding
domain; has similarity to human hCsl4p (EXOSC1)"
/codon_start=1
/product="Csl4p"
/protein_id="NP_014167.1"
/db_xref="GI:6324097"
/db_xref="SGD:S000005176"
/db_xref="GeneID:855489"
/translation="MACNFQFPEIAYPGKLICPQYGTENKDGEDIIFNYVPGPGTKLI
QYEHNGRTLEAITATLVGTVRCEEEKKTDQEEEREGTDQSTEEEKSVDASPNDVTRRT
VKNILVSVLPGTEKGRKTNKYANNDFANNLPKEGDIVLTRVTRLSLQRANVEILAVED
KPSPIDSGIGSNGSGIVAAGGGSGAATFSVSQASSDLGETFRGIIRSQDVRSTDRDRV
KVIECFKPGDIVRAQVLSLGDGTNYYLTTARNDLGVVFARAANGAGGLMYATDWQMMT
SPVTGATEKRKCAKPF"
gene complement(215987..217042)
/gene="PDR16"
/locus_tag="YNL231C"
/gene_synonym="SFH3"
/db_xref="GeneID:855490"
mRNA complement(215987..217042)
/gene="PDR16"
/locus_tag="YNL231C"
/gene_synonym="SFH3"
/product="Pdr16p"
/transcript_id="NM_001183069.1"
/db_xref="GI:296147547"
/db_xref="GeneID:855490"
CDS complement(215987..217042)
/gene="PDR16"
/locus_tag="YNL231C"
/gene_synonym="SFH3"
/note="Phosphatidylinositol transfer protein (PITP);
controlled by the multiple drug resistance regulator
Pdr1p; localizes to lipid particles and microsomes;
controls levels of various lipids, may regulate lipid
synthesis; homologous to Pdr17p; protein abundance
increases in response to DNA replication stress"
/codon_start=1
/product="Pdr16p"
/protein_id="NP_014168.1"
/db_xref="GI:6324098"
/db_xref="SGD:S000005175"
/db_xref="GeneID:855490"
/translation="MFKRFSKKKEAPEDPKNLINIDKPIKELPASIAIPKEKPLTGEQ
QKMYDEVLKHFSNPDLKVYTSEKNKSEDDLKPLEEEEKAWLTRECFLRYLRATKWVLK
DCIDRITMTLAWRREFGISHLGEEHGDKITADLVAVENESGKQVILGYENDARPILYL
KPGRQNTKTSHRQVQHLVFMLERVIDFMPAGQDSLALLIDFKDYPDVPKVPGNSKIPP
IGVGKEVLHILQTHYPERLGKALLTNIPWLAWTFLKLIHPFIDPLTREKLVFDEPFVK
YVPKNELDSLYGGDLKFKYNHDVYWPALVETAREKRDHYFKRFQSFGGIVGLSEVDLR
GTHEKLLYPVKSESSTV"
gene complement(217523..218662)
/gene="ELA1"
/locus_tag="YNL230C"
/db_xref="GeneID:855491"
mRNA complement(217523..218662)
/gene="ELA1"
/locus_tag="YNL230C"
/product="Ela1p"
/transcript_id="NM_001183068.1"
/db_xref="GI:296147548"
/db_xref="GeneID:855491"
CDS complement(217523..218662)
/gene="ELA1"
/locus_tag="YNL230C"
/note="Elongin A; F-box protein that forms a heterodimer
with Elc1p and is required for ubiquitin-dependent
degradation of the RNA Polymerase II subunit Rpo21p;
subunit of the Elongin-Cullin-Socs (ECS) ligase complex"
/codon_start=1
/product="elongin A"
/protein_id="NP_014169.1"
/db_xref="GI:6324099"
/db_xref="SGD:S000005174"
/db_xref="GeneID:855491"
/translation="MKSLQTLCEISLMRNHSNIQSVSNVPYHLLKRILQKVKIPQLLK
LEKSNVLLIFDDDELWLEFLRQDFPTNVHEQFVSKRDIICKYYFDFVKENDIELYHSN
QDLLKSCVRQSVVKDIRNNKYRIPYRMLYSKYQQEVEKKQEESAERLRLEMQKLQQER
EKKQTIVVDHTVYFKKRNTKKTTRLHNEPHSQLYMKSLKDHESRLKHFKDGGFNIAKR
HAQRVAFGGQAGGQSSSPKKGPLSIKPEPVKVNRQMDNVTAEKKDVTQPITPVKKRRS
ESPSIFLNRKKPALFRPTPKTNAAGSRPHTTAITNDHRTTSHPYPHKDVVTSISSVTA
NPVTKGHKKKKSGIFVRNAGSDGDSFPHVTATGPTTRPYIYEPRK"
gene complement(219137..220201)
/gene="URE2"
/locus_tag="YNL229C"
/db_xref="GeneID:855492"
mRNA complement(219137..220201)
/gene="URE2"
/locus_tag="YNL229C"
/product="Ure2p"
/transcript_id="NM_001183067.1"
/db_xref="GI:296147549"
/db_xref="GeneID:855492"
CDS complement(219137..220201)
/gene="URE2"
/locus_tag="YNL229C"
/note="Nitrogen catabolite repression transcriptional
regulator that acts by inhibition of GLN3 transcription in
good nitrogen source; has glutathione peroxidase activity
and can mutate to acquire GST activity; altered form
creates [URE3] prion"
/codon_start=1
/product="Ure2p"
/protein_id="NP_014170.1"
/db_xref="GI:6324100"
/db_xref="SGD:S000005173"
/db_xref="GeneID:855492"
/translation="MMNNNGNQVSNLSNALRQVNIGNRNSNTTTDQSNINFEFSTGVN
NNNNNNSSSNNNNVQNNNSGRNGSQNNDNENNIKNTLEQHRQQQQAFSDMSHVEYSRI
TKFFQEQPLEGYTLFSHRSAPNGFKVAIVLSELGFHYNTIFLDFNLGEHRAPEFVSVN
PNARVPALIDHGMDNLSIWESGAILLHLVNKYYKETGNPLLWSDDLADQSQINAWLFF
QTSGHAPMIGQALHFRYFHSQKIASAVERYTDEVRRVYGVVEMALAERREALVMELDT
ENAAAYSAGTTPMSQSRFFDYPVWLVGDKLTIADLAFVPWNNVVDRIGINIKIEFPEV
YKWTKHMMRRPAVIKALRGE"
gene complement(220659..222431)
/gene="JJJ1"
/locus_tag="YNL227C"
/db_xref="GeneID:855495"
mRNA complement(220659..222431)
/gene="JJJ1"
/locus_tag="YNL227C"
/product="Jjj1p"
/transcript_id="NM_001183065.1"
/db_xref="GI:296147550"
/db_xref="GeneID:855495"
CDS complement(220659..222431)
/gene="JJJ1"
/locus_tag="YNL227C"
/note="Co-chaperone that stimulates the ATPase activity of
Ssa1p, required for a late step of ribosome biogenesis;
associated with the cytosolic large ribosomal subunit;
contains a J-domain; mutation causes defects in
fluid-phase endocytosis"
/codon_start=1
/product="Jjj1p"
/protein_id="NP_014172.1"
/db_xref="GI:6324103"
/db_xref="SGD:S000005171"
/db_xref="GeneID:855495"
/translation="MKTCYYELLGVETHASDLELKKAYRKKALQYHPDKNPDNVEEAT
QKFAVIRAAYEVLSDPQERAWYDSHKEQILNDTPPSTDDYYDYEVDATVTGVTTDELL
LFFNSALYTKIDNSAAGIYQIAGKIFAKLAKDEILSGKRLGKFSEYQDDVFEQDINSI
GYLKACDNFINKTDKLLYPLFGYSPTDYEYLKHFYKTWSAFNTLKSFSWKDEYMYSKN
YDRRTKREVNRRNEKARQQARNEYNKTVKRFVVFIKKLDKRMKEGAKIAEEQRKLKEQ
QRKNELNNRRKFGNDNNDEEKFHLQSWQTVKEENWDELEKVYDNFGEFENSKNDKEGE
VLIYECFICNKTFKSEKQLKNHINTKLHKKNMEEIRKEMEEENITLGLDNLSDLEKFD
SADESVKEKEDIDLQALQAELAEIERKLAESSSEDESEDDNLNIEMDIEVEDVSSDEN
VHVNTKNKKKRKKKKKAKVDTETEESESFDDTKDKRSNELDDLLASLGDKGLQTDDDE
DWSTKAKKKKGKQPKKNSKSTKSTPSLSTLPSSMSPTSAIEVCTTCGESFDSRNKLFN
HVKIAGHAAVKNVVKRKKVKTKRI"
gene complement(222724..224469)
/gene="CNM67"
/locus_tag="YNL225C"
/db_xref="GeneID:855496"
mRNA complement(222724..224469)
/gene="CNM67"
/locus_tag="YNL225C"
/product="Cnm67p"
/transcript_id="NM_001183063.1"
/db_xref="GI:296147551"
/db_xref="GeneID:855496"
CDS complement(222724..224469)
/gene="CNM67"
/locus_tag="YNL225C"
/note="Component of the spindle pole body outer plaque;
required for spindle orientation and mitotic nuclear
migration; CNM67 has a paralog, ADY3, that arose from the
whole genome duplication"
/codon_start=1
/product="Cnm67p"
/protein_id="NP_014174.1"
/db_xref="GI:6324104"
/db_xref="SGD:S000005169"
/db_xref="GeneID:855496"
/translation="MTDFDLMNFPFHERLDSPVSENGEIKDGEPIPQNWLNENHVGKS
ILPLFVNPEDVINCNFSNARDSYEENKSPSMDQMNYARNTSYQESPGLQERPKNEKDK
SPIGTDVHKKDVPNFIHSTPRENSSKHFTRANEQASAQPTDEHTSPDISIEDCNGAKI
FLQNSLSKEDFRMLENVILGYQKKVIELGRDNLRQEERANSLQKELEAATKSNDKTLD
NKKKIEEQTVLIENLTKDLSLNKEMLEKANDTIQTKHTALLSLTDSLRKAELFEIPIG
ILFFDLYDSEENSSKLDHILQEKYPNIKGFLCASQQEELSRISQRFKNAKAEAEDLRN
ELENKKIEIQTMREKNNTLIGTNKTLSKQNKILCDKFDKLTIDEKEILKGCNEEIKIK
LERLNERLGSWEKSKEKYETSLKDKEKMLADAEKKTNTLSKELDNLRSRFGNLEGNTS
ERITIKNILQSRPDISAEECNFLMVEQIDSANLTTLQNTVKEIVLAVGIPYPKLRRKI
PLLAIKLKYENIMLSNFAQRLHRQVYSQEMNLKKFTDQAYYDFMSTRRMDSIDHHLER
CLDHLYDHILEKMVK"
gene complement(224796..227099)
/gene="SQS1"
/locus_tag="YNL224C"
/gene_synonym="PFA1"
/db_xref="GeneID:855497"
mRNA complement(224796..227099)
/gene="SQS1"
/locus_tag="YNL224C"
/gene_synonym="PFA1"
/product="Sqs1p"
/transcript_id="NM_001183062.1"
/db_xref="GI:296147552"
/db_xref="GeneID:855497"
CDS complement(224796..227099)
/gene="SQS1"
/locus_tag="YNL224C"
/gene_synonym="PFA1"
/note="Protein that stimulates the ATPase and helicase
activities of Prp43p; acts with Prp43p to stimulate 18s
rRNA maturation by Nob1p; overexpression antagonizes the
suppression of splicing defects by spp382 mutants;
component of pre-ribosomal particles; relocalizes from
nucleus to nucleolus upon DNA replication stress"
/codon_start=1
/product="Sqs1p"
/protein_id="NP_014175.1"
/db_xref="GI:6324105"
/db_xref="SGD:S000005168"
/db_xref="GeneID:855497"
/translation="MAKRHSHYQGSRRRHARGSNSKKAGRGNAKGIQGRKIKKKPTPT
NSWHNSSIPLGEGDLDDVGADFNPGRAFISPKTIEDYYFGRDAKSRSMKMGGLRPGNR
YDSSTDLQAGRAAFRKRPMQFVKAKEVYDPSHNMIQKLRAKNETKNSEEIVEREADVF
EEPGKMTSDVEYINNEDSENEDDDSQNSPSTDHSLSSNESKVEDGDLFFVDEEAQQSP
DLTKIKRVCIEEIARPREVAIEFDPILTIGKVELSVSEGNESKEISVDVPNKGNKTYH
PFAGYISNVLHGMHTSDSDNDELDYEIETENNSEPLYESSASSEVDQGFNYVGQRHNS
RADNNLLPSPSPQLTEDIKCLSINGTKTFEGNNDNLPSPASEELEFGFKEEDFVINTN
DIVVSNIRMGGVDNSYYLRCYRLLGDYDFHWIDQDLLTDFVVDELGLPEDRLPAYLNF
IKNSLIPKIEPAEPTYSDIPISDSSDEGDSYEGDSYEDDEDMASSVVHSDIEEGLDDL
IAYTLKHDTERFKTFETKSLETKGKGKKKKLLIDDALALDTETLETLQSKFSKRIETK
AKKRKAKEDFIDQENRNSNDMLKKYPYGLHIQNIKDEFESFLSRNNDRLTFPPLDPHG
NKTVMKIAKHYNMKSSKIGKANHTSVVVEKIKKTKWSSPNYSLIDQLMRQRPVFMRID
IRRPREEQAAFERTKTIRGKFHVKEGEIVGQNAPEIGNENIGRRMLEKLGWKSGEGLG
IQGNKGISEPIFAKIKKNRSGLRHSES"
gene 227370..228854
/gene="ATG4"
/locus_tag="YNL223W"
/gene_synonym="APG4; AUT2"
/db_xref="GeneID:855498"
mRNA 227370..228854
/gene="ATG4"
/locus_tag="YNL223W"
/gene_synonym="APG4; AUT2"
/product="Atg4p"
/transcript_id="NM_001183061.1"
/db_xref="GI:296147553"
/db_xref="GeneID:855498"
CDS 227370..228854
/gene="ATG4"
/locus_tag="YNL223W"
/gene_synonym="APG4; AUT2"
/EC_number="3.4.22.-"
/note="Conserved cysteine protease required for autophagy;
cleaves Atg8p to a form required for autophagosome and Cvt
vesicle generation"
/codon_start=1
/product="Atg4p"
/protein_id="NP_014176.2"
/db_xref="GI:37362688"
/db_xref="SGD:S000005167"
/db_xref="GeneID:855498"
/translation="MQRWLQLWKMDLVQKVSHGVFEGSSEEPAALMNHDYIVLGEVYP
ERDEESGAEQCEQDCRYRGEAVSDGFLSSLFGREISSYTKEFLLDVQSRVNFTYRTRF
VPIARAPDGPSPLSLNLLVRTNPISTIEDYIANPDCFNTDIGWGCMIRTGQSLLGNAL
QILHLGRDFRVNGNESLERESKFVNWFNDTPEAPFSLHNFVSAGTELSDKRPGEWFGP
AATARSIQSLIYGFPECGIDDCIVSVSSGDIYENEVEKVFAENPNSRILFLLGVKLGI
NAVNESYRESICGILSSTQSVGIAGGRPSSSLYFFGYQGNEFLHFDPHIPQPAVEDSF
VESCHTSKFGKLQLSEMDPSMLIGILIKGEKDWQQWKLEVAESAIINVLAKRMDDFDV
SCSMDDVESVSSNSMKKDASNNENLGVLEGDYVDIGAIFPHTTNTEDVDEYDCFQDIH
CKKQKIVVMGNTHTVNANLTDYEVEGVLVEKETVGIHSPIDEKC"
gene 229094..229714
/gene="SSU72"
/locus_tag="YNL222W"
/db_xref="GeneID:855499"
mRNA 229094..229714
/gene="SSU72"
/locus_tag="YNL222W"
/product="Ssu72p"
/transcript_id="NM_001183060.1"
/db_xref="GI:296147554"
/db_xref="GeneID:855499"
CDS 229094..229714
/gene="SSU72"
/locus_tag="YNL222W"
/EC_number="3.1.3.16"
/note="Transcription/RNA-processing factor that associates
with TFIIB and cleavage/polyadenylation factor Pta1p;
exhibits phosphatase activity on serine-5 of the RNA
polymerase II C-terminal domain; affects start site
selection in vivo"
/codon_start=1
/product="Ssu72p"
/protein_id="NP_014177.1"
/db_xref="GI:6324107"
/db_xref="SGD:S000005166"
/db_xref="GeneID:855499"
/translation="MPSHRNSNLKFCTVCASNNNRSMESHKVLQEAGYNVSSYGTGSA
VRLPGLSIDKPNVYSFGTPYNDIYNDLLSQSADRYKSNGLLQMLDRNRRLKKAPEKWQ
ESTKVFDFVFTCEERCFDAVCEDLMNRGGKLNKIVHVINVDIKDDDENAKIGSKAILE
LADMLNDKIEQCEKDDIPFEDCIMDILTEWQSSHSQLPSLYAPSYY"
gene complement(230105..230672)
/locus_tag="snR19"
/db_xref="GeneID:9164965"
ncRNA complement(230105..230672)
/locus_tag="snR19"
/ncRNA_class="snRNA"
/product="SNR19"
/note="U1 spliceosomal RNA (U1 snRNA); snRNA U1 homolog"
/db_xref="SGD:S000007295"
/db_xref="GeneID:9164965"
gene complement(231068..233695)
/gene="POP1"
/locus_tag="YNL221C"
/db_xref="GeneID:855500"
mRNA complement(231068..233695)
/gene="POP1"
/locus_tag="YNL221C"
/product="Pop1p"
/transcript_id="NM_001183059.1"
/db_xref="GI:296147555"
/db_xref="GeneID:855500"
CDS complement(231068..233695)
/gene="POP1"
/locus_tag="YNL221C"
/EC_number="3.1.26.5"
/note="Subunit of both RNase MRP and nuclear RNase P;
RNase MRP cleaves pre-rRNA, while nuclear RNase P cleaves
tRNA precursors to generate mature 5' ends and facilitates
turnover of nuclear RNAs; binds to the RPR1 RNA subunit in
RNase P"
/codon_start=1
/product="Pop1p"
/protein_id="NP_014178.1"
/db_xref="GI:6324108"
/db_xref="SGD:S000005165"
/db_xref="GeneID:855500"
/translation="MSGSLSRGNGGKKVLNKNQLLKRNRIRNARSIRAEAVAASSTKT
GTPSDLSESGSKLNVDQFISSRQFEVKQLQLAMHNSKAASSTRIFQALPRKLRRRTAS
HNVRRIPKRMRNRALREMRKSDQQDVLKGSSASSRKAHGLNAKQLYKARMSIKLLRLA
SKSTSMKLSMPPEVTSSNCHVRQKIKTLKRMIKESSTANPNIKLLNNRMGSYDCTGVN
ELAPIPKGRVKYTKRQKHFAWLPTHIWNAKRSHMMKRWGYQMVWAPTQKCFKLTHRLG
GDTCSSDGALCMDSSYIGTIIVKDKSNDSEGDFLKSIIGKLTAERANLRKYREGQVLF
QGLIYSFNEENGEDSTKPLGPCDVFWVQKDTAIIRLHPSIYTQVFNILLQHKEKLTVQ
DCRYSLASVTLKGAKALESLASCLRSTEYSKSFEQFKMVSMITDHNALPQRCTFAFEA
IDPRHLAAPKKLNDSQRKTVNSDDILSLHENYPQDEINAVFNELCDPESRTQSYNNQN
TLKEISARRYKLLTATPNSINKTTVPFKESDDPSIPLVIIRRLKTRDWIVVLPWFWLL
PLWHLLNRIPRMYHIGLRQFQQIQYENKQLYFPDDYPFTQLGYIENSFYKKEASKTKW
DRKPMGKRINFEKIKDIHNTKLPAYSGEIGDFFSSDWRFLQILRNGIDYLQRNDKTLE
LMDSKKTGQFNAQGVRDINCVNDVLEFCKDYEAKTKAMSLSIEENIPVALCKNRKCQF
RTPDSISVNSSSFSLTFFPRCIIAVSCTLLERGHPKDNARIYQVPEKDLEHWLQLAKG
VYRPNGRKDHDLKIPLPEVHDLIGFITSGTYHLNCGNGMGIGFIDHHAAIRQPTRYVL
IRNVGTNTYRLGEWSKISV"
gene 234413..235714
/gene="ADE12"
/locus_tag="YNL220W"
/gene_synonym="BRA9"
/db_xref="GeneID:855501"
mRNA 234413..235714
/gene="ADE12"
/locus_tag="YNL220W"
/gene_synonym="BRA9"
/product="adenylosuccinate synthase"
/transcript_id="NM_001183058.1"
/db_xref="GI:296147556"
/db_xref="GeneID:855501"
CDS 234413..235714
/gene="ADE12"
/locus_tag="YNL220W"
/gene_synonym="BRA9"
/EC_number="6.3.4.4"
/note="Adenylosuccinate synthase, catalyzes the first step
in synthesis of adenosine monophosphate from inosine
5'monophosphate during purine nucleotide biosynthesis;
exhibits binding to single-stranded autonomously
replicating (ARS) core sequence"
/codon_start=1
/product="adenylosuccinate synthase"
/protein_id="NP_014179.1"
/db_xref="GI:6324109"
/db_xref="SGD:S000005164"
/db_xref="GeneID:855501"
/translation="MVNVVLGSQWGDEGKGKLVDLLVGKYDIVARCAGGNNAGHTIVV
DGVKYDFHMLPSGLVNPNCQNLLGNGVVIHVPSFFKELETLEAKGLKNARSRLFVSSR
AHLVFDFHQVTDKLRELELSGRSKDGKNIGTTGKGIGPTYSTKASRSGLRVHHLVNDQ
PGAWEEFVARYKRLLETRRQRYGDFEYDFEAKLAEYKKLREQLKPFVVDSVVFMHNAI
EAKKKILVEGANALMLDIDFGTYPYVTSSNTGIGGVLTGLGIPPRTIDEIYGVVKAYT
TRVGEGPFPTEQLNENGEKLQTIGAEFGVTTGRKRRCGWLDLVVLKYSTLINGYTSLN
ITKLDVLDTFKEIPVGISYSIQGKKLDLFPEDLNILGKVEVEYKVLPGWDQDITKITK
YEDLPENAKKYLKYIEDFVGVPVEWVGTGPARESMLHKEIK"
gene complement(235996..237663)
/gene="ALG9"
/locus_tag="YNL219C"
/db_xref="GeneID:855502"
mRNA complement(235996..237663)
/gene="ALG9"
/locus_tag="YNL219C"
/product="dolichyl-P-Man:Man(6)GlcNAc(2)-PP-dolichol
alpha-1,2-mannosyltransferase"
/transcript_id="NM_001183057.1"
/db_xref="GI:296147557"
/db_xref="GeneID:855502"
CDS complement(235996..237663)
/gene="ALG9"
/locus_tag="YNL219C"
/note="Mannosyltransferase, involved in N-linked
glycosylation; catalyzes both the transfer of seventh
mannose residue on B-arm and ninth mannose residue on the
C-arm from Dol-P-Man to lipid-linked oligosaccharides;
mutation of the human ortholog causes type 1 congenital
disorders of glycosylation"
/codon_start=1
/product="dolichyl-P-Man:Man(6)GlcNAc(2)-PP-dolichol
alpha-1,2-mannosyltransferase"
/protein_id="NP_014180.1"
/db_xref="GI:6324110"
/db_xref="SGD:S000005163"
/db_xref="GeneID:855502"
/translation="MNCKAVTISLLLLLFLTRVYIQPTFSLISDCDETFNYWEPLNLL
VRGFGKQTWEYSPEYSIRSWAFLLPFYCILYPVNKFTDLESHWNFFITRACLGFFSFI
MEFKLHREIAGSLALQIANIWIIFQLFNPGWFHASVELLPSAVAMLLYVGATRHSLRY
LSTGSTSNFTKSLAYNFLASILGWPFVLILSLPLCLHYLFNHRIISTIRTAFDCCLIF
SLTAFAVIVTDSIFYGKLAPVSWNILFYNVINASEESGPNIFGVEPWYYYPLNLLLNF
PLPVLVLAILGIFHLRLWPLWASLFTWIAVFTQQPHKEERFLYPIYGLITLSASIAFY
KVLNLFNRKPILKKGIKLSVLLIVAGQAMSRIVALVNNYTAPIAVYEQFSSLNQGGVK
APVVNVCTGREWYHFPSSFLLPDNHRLKFVKSGFDGLLPGDFPESGSIFKKIRTLPKG
MNNKNIYDTGKEWPITRCDYFIDIVAPINLTKDVFNPLHLMDNWNKLACAAFIDGENS
KILGRAFYVPEPINRIMQIVLPKQWNQVYGVRYIDYCLFEKPTETTN"
gene 238238..240001
/gene="MGS1"
/locus_tag="YNL218W"
/db_xref="GeneID:855503"
mRNA 238238..240001
/gene="MGS1"
/locus_tag="YNL218W"
/product="ssDNA-dependent ATPase MGS1"
/transcript_id="NM_001183056.1"
/db_xref="GI:296147558"
/db_xref="GeneID:855503"
CDS 238238..240001
/gene="MGS1"
/locus_tag="YNL218W"
/note="Protein with DNA-dependent ATPase and ssDNA
annealing activities; involved in maintenance of genome;
interacts functionally with DNA polymerase delta; homolog
of human Werner helicase interacting protein (WHIP); forms
nuclear foci upon DNA replication stress"
/codon_start=1
/product="ssDNA-dependent ATPase MGS1"
/protein_id="NP_014181.1"
/db_xref="GI:6324111"
/db_xref="SGD:S000005162"
/db_xref="GeneID:855503"
/translation="MSNKRTSVEQLISCPICSRKVFFSLINSHLDICGKEKSKPSSRP
QTVSSLLAGPKKRKQANSEKFIDLENKDHEIKPGLKSESDDIEIVENESKRFKAAPST
DFAKSIVEPASSRDQLHNDYESRWLQKISHLPLSEKLRPKELRDYVGQQHILSQDNGT
LFKYIKQGTIPSMILWGPPGVGKTSLARLLTKTATTSSNESNVGSRYFMIETSATKAN
TQELRGIFEKSKKEYQLTKRRTVLFIDEIHRFNKVQQDLLLPHVENGDIILIGATTEN
PSFQLNNALISRCLIFVLEKLNVNELCIVLSRGIALLNKCRKQVWNIENPLKLSRSIL
EYVVDLSVGDTRRALNMLEMIEVSTRERKADEEELSIDDVRDIIKNNSSNGLNTYYDP
KGDNHYDTISAFHKSIRGGDENASLYYLARMLQGGEDPLYVARRMIRIASEDIGLRDS
SLLPLAVAAHDAVMKVGLPEADLALAQCCVALARAPKSVELYRAWKKLRAMMSENMYS
LASSEIPMHIRNAPTKLMEELGYHKGYKYNPDYIEGKVQQDYFPKEVLEKCPNKTDLK
FLDGKHLGDKEDPDLRQSYQG"
gene 240331..241311
/locus_tag="YNL217W"
/db_xref="GeneID:855504"
mRNA 240331..241311
/locus_tag="YNL217W"
/product="putative serine/threonine-protein phosphatase"
/transcript_id="NM_001183055.1"
/db_xref="GI:296147559"
/db_xref="GeneID:855504"
CDS 240331..241311
/locus_tag="YNL217W"
/EC_number="3.1.-.-"
/note="hypothetical protein; weak sequence similarity to
bis (5'-nucleotidyl)-tetraphosphatases; (GFP)-fusion
protein localizes to the vacuole; null mutant is highly
sensitive to azaserine and resistant to sodium-O-vandate"
/codon_start=1
/product="putative serine/threonine-protein phosphatase"
/protein_id="NP_014182.1"
/db_xref="GI:6324112"
/db_xref="SGD:S000005161"
/db_xref="GeneID:855504"
/translation="MEDKRKRRAATLSTALILFVACCVYTLYIFKFDNPRLSPPVSLL
PTISTLKKIEHVTDLNKEYVFVGDVHGNYDEFIELIDDKIGGLGENITMILLGDFIHK
GPDSDKVVSYILNHKDQVKCVLGNHEILVMMAYLNPDFSKWVRRPKLMTPLTFSTETN
FIPQDISKISNAHGRLARELGFSKLSQLAEHCSMAIELDLDITGDILFGAHAGMVPGD
FMKPNQIPGVSSLSNMKYVDKKNWSKTSREKENKNYVRWYTLWDKYGDHFSNAKVFYG
HDASMGLNLRRQTKGLDTACIKNNLLSSMKVKYDIKKGQYDYELIQVQCS"
gene 241689..244172
/gene="RAP1"
/locus_tag="YNL216W"
/gene_synonym="GRF1; TBA1; TUF1"
/db_xref="GeneID:855505"
mRNA 241689..244172
/gene="RAP1"
/locus_tag="YNL216W"
/gene_synonym="GRF1; TBA1; TUF1"
/product="Rap1p"
/transcript_id="NM_001183054.1"
/db_xref="GI:296147560"
/db_xref="GeneID:855505"
CDS 241689..244172
/gene="RAP1"
/locus_tag="YNL216W"
/gene_synonym="GRF1; TBA1; TUF1"
/note="Essential DNA-binding transcription regulator that
binds at many loci; involved in either transcription
activation or repression, chromatin silencing, and
telomere length maintenance; conserved protein with an
N-terminal BRCT domain, a central region with homology to
the Myb DNA binding domain, and a C-terminal Rap1-specific
protein-interaction domain (RCT domain)"
/codon_start=1
/product="Rap1p"
/protein_id="NP_014183.1"
/db_xref="GI:6324113"
/db_xref="SGD:S000005160"
/db_xref="GeneID:855505"
/translation="MSSPDDFETAPAEYVDALDPSMVVVDSGSAAVTAPSDSAAEVKA
NQNEENTGATAAETSEKVDQTEVEKKDDDDTTEVGVTTTTPSIADTAATANIASTSGA
SVTEPTTDDTAADEKKEQVSGPPLSNMKFYLNRDADAHDSLNDIDQLARLIRANGGEV
LDSKPRESKENVFIVSPYNHTNLPTVTPTYIKACCQSNSLLNMENYLVPYDNFREVVD
SRLQEESHSNGVDNSNSNSDNKDSIRPKTEIISTNTNGATEDSTSEKVMVDAEQQARL
QEQAQLLRQHVSSTASITSGGHNDLVQIEQPQKDTSNNNNSNVNDEDNDLLTQDNNPQ
TADEGNASFQAQRSMISRGALPSHNKASFTDEEDEFILDVVRKNPTRRTTHTLYDEIS
HYVPNHTGNSIRHRFRVYLSKRLEYVYEVDKFGKLVRDDDGNLIKTKVLPPSIKRKFS
ADEDYTLAIAVKKQFYRDLFQIDPDTGRSLITDEDTPTAIARRNMTMDPNHVPGSEPN
FAAYRTQSRRGPIAREFFKHFAEEHAAHTENAWRDRFRKFLLAYGIDDYISYYEAEKA
QNREPEPMKNLTNRPKRPGVPTPGNYNSAAKRARNYSSQRNVQPTANAASANAAAAAA
AAASNSYAIPENELLDEDTMNFISSLKNDLSNISNSLPFEYPHEIAEAIRSDFSNEDI
YDNIDPDTISFPPKIATTDLFLPLFFHFGSTRQFMDKLHEVISGDYEPSQAEKLVQDL
CDETGIRKNFSTSILTCLSGDLMVFPRYFLNMFKDNVNPPPNVPGIWTHDDDESLKSN
DQEQIRKLVKKHGTGRMEMRKRFFEKDLL"
gene 244468..245430
/gene="IES2"
/locus_tag="YNL215W"
/db_xref="GeneID:855506"
mRNA 244468..245430
/gene="IES2"
/locus_tag="YNL215W"
/product="Ies2p"
/transcript_id="NM_001183053.1"
/db_xref="GI:296147561"
/db_xref="GeneID:855506"
CDS 244468..245430
/gene="IES2"
/locus_tag="YNL215W"
/note="Protein that associates with the INO80 chromatin
remodeling complex; associates with the INO80 complex
under low-salt conditions; essential for growth under
anaerobic conditions; protein abundance increases in
response to DNA replication stress"
/codon_start=1
/product="Ies2p"
/protein_id="NP_014184.1"
/db_xref="GI:6324114"
/db_xref="SGD:S000005159"
/db_xref="GeneID:855506"
/translation="MDSEASDIEAELSDSVSAGGEEYIDDDDYTEDIDDQIVTAKSSR
RTARRSVPKGVRTSKRIRDKELSVEVDEDYDEEEDVLSPSKKRHLHTRSMDKRQVAAT
ASEKSDIGDSKGNDGEIEDGILEEEESLEKELNRGGGKEVEKSEESYYAQNDVGQKGE
EEQDGESGGYEDNEPSISKESDELVSVVNGNGNEEDDEVEATKENTTDSTRSTTTRSK
MLLDLLEDGGSKKKLTDEEIQLRRAENARKRKNLSEKRLEEEKQDTINKLLKKRAGKS
RSHLPNDDEKNDGSSSFVKPRRPYNSEGMTRILRRYEEDLFCTF"
gene 245617..246216
/gene="PEX17"
/locus_tag="YNL214W"
/gene_synonym="PAS9"
/db_xref="GeneID:855507"
mRNA 245617..246216
/gene="PEX17"
/locus_tag="YNL214W"
/gene_synonym="PAS9"
/product="Pex17p"
/transcript_id="NM_001183052.1"
/db_xref="GI:296147562"
/db_xref="GeneID:855507"
CDS 245617..246216
/gene="PEX17"
/locus_tag="YNL214W"
/gene_synonym="PAS9"
/note="Peroxisomal membrane peroxin and subunit of the
docking complex that facilitates the import of peroxisomal
matrix proteins; required for peroxisome biogenesis"
/codon_start=1
/product="Pex17p"
/protein_id="NP_014185.1"
/db_xref="GI:6324115"
/db_xref="SGD:S000005158"
/db_xref="GeneID:855507"
/translation="MTSINSFPRNIDWPSNIGIKKIEGTNPTVNAIKGLLYNGGSIYA
FLYFVIAMFVEPTLQKQYQQRNDFSLFVLLRLRRIIAQLQKRLVMTPVSSLGFNEQNN
FVERSTQTSDDNIIREDNSHWAEMIYQLQNMKQELQYFNRSSGQPSESIDDFVFQIKM
VTDQVELTDRSRAFSNKSRNIIQGIREIKGWFVNGQVPR"
gene complement(246460..247104)
/gene="RRG9"
/locus_tag="YNL213C"
/db_xref="GeneID:855508"
mRNA complement(246460..247104)
/gene="RRG9"
/locus_tag="YNL213C"
/product="Rrg9p"
/transcript_id="NM_001183051.1"
/db_xref="GI:296147563"
/db_xref="GeneID:855508"
CDS complement(246460..247104)
/gene="RRG9"
/locus_tag="YNL213C"
/note="hypothetical protein; null mutant lacks
mitochondrial DNA and cannot grow on glycerol; the
authentic, non-tagged protein is detected in highly
purified mitochondria in high-throughput studies"
/codon_start=1
/product="Rrg9p"
/protein_id="NP_014186.1"
/db_xref="GI:6324116"
/db_xref="SGD:S000005157"
/db_xref="GeneID:855508"
/translation="MNILRIACRSFHCLRCGPLLNENRGWSSKKIIKLVNKSSLSNKE
FTEKVRDGTKDIPEWKKQKMAVRKKLQGQRWNPPKKISQEQMEALRLLKFNFPELTAS
DLADRFKISPEAVRRILKSNWKRTDEENNNTYERWKRRGERIKEMYQRKEDADFVSNQ
IVTSRKIILGSNSNSPELIARNVRTFKPFKPNNSTPEKKNTNKLYILKHLGSKQ"
gene 247461..249809
/gene="VID27"
/locus_tag="YNL212W"
/db_xref="GeneID:855509"
mRNA 247461..249809
/gene="VID27"
/locus_tag="YNL212W"
/product="Vid27p"
/transcript_id="NM_001183050.1"
/db_xref="GI:296147564"
/db_xref="GeneID:855509"
CDS 247461..249809
/gene="VID27"
/locus_tag="YNL212W"
/note="Cytoplasmic hypothetical protein; possibly involved
in vacuolar protein degradation; not essential for
proteasome-dependent degradation of
fructose-1,6-bisphosphatase (FBPase); null mutants exhibit
normal growth"
/codon_start=1
/product="Vid27p"
/protein_id="NP_014187.1"
/db_xref="GI:6324117"
/db_xref="SGD:S000005156"
/db_xref="GeneID:855509"
/translation="MNILKKFMESGNKPELITIPSGQFNLLRSKNSPKAALECIYNNA
TLSVRKIGKFDYELAVYRVEDDSEGGTGDEAENFEDDTISVLSTQSKKKEEEWSVEIS
DKIMFHKTWDKQGNVALVWENLRGDEQDEKVQFVVAADVSFSDVEQFIQTVYRCQFEV
RNKKSSLTASADDLKEIEHRSTRLFVQDDDDELDSSSDDFQDAKDTSFEHEKESEILE
RTPSPLKKVPEGEYCCLVMSSLYMYDPIQEKFILQEPVVKVAIIDTGKYEFWLAIEGK
DNRLGTQVAPNINPTFELATDAFLFNYTLQNITLSYMLKFKDLDKCIQFRFAWVKCLW
MTLNKETWTDVPEKEKDYILDSSSVPLEKQFDDILHIDDRSNEERDKESSESENDSED
EDDENDHSKRIISSEAFEEPRRATSKGNSSLTVAFRNNRSYVTRDNRIGVFKTDDEDD
SLEFVAAIKNISNLGGKSIDPHKPMLYMEDRNLILTDGENENKLYKMDIERGKVIEEW
STGDKNVVQYGPTKKFDQMTPEQTIVGVSQKGVFKIDPRINGKNKIAVDESKDYVGKY
NFSSIGTTESGYIAIGSEKGDIKLYDRLGIRAKTAIPSLGQAIKFITTSADGKWLLAT
CESTLLLMDLKIKDGKNAGNIGFLKSFPASENVKTYVLKIRPEHSASILTYTKKPIRF
TKAYFNTGIGQQEQTIVTSTGPYAISWSLKGILNQDGSNNYPYRIRRYNADVVADNFE
FGSDKKVIVALKDDVSLSKVKSFKQPSKGVLMPSASLQDFYG"
gene complement(250055..250315)
/locus_tag="YNL211C"
/db_xref="GeneID:855510"
mRNA complement(250055..250315)
/locus_tag="YNL211C"
/product="hypothetical protein"
/transcript_id="NM_001183049.1"
/db_xref="GI:296147565"
/db_xref="GeneID:855510"
CDS complement(250055..250315)
/locus_tag="YNL211C"
/note="hypothetical protein; green fluorescent protein
(GFP)-fusion protein localizes to mitochondria; YNL211C is
not an essential gene"
/codon_start=1
/product="hypothetical protein"
/protein_id="NP_014188.1"
/db_xref="GI:6324118"
/db_xref="SGD:S000005155"
/db_xref="GeneID:855510"
/translation="MPPRSIEEWFYYKLLSSPGFHRFVRKVYRKVNGIKEDPFTDQST
AFQYLYKPTPRQKFKALRLLFWDEMRSTFGFRRRLGDRFKKD"
rep_origin 250315..250931
/note="ARS1413;
ARS activated in late S phase"
/db_xref="SGD:S000077375"
gene 250931..251743
/gene="MER1"
/locus_tag="YNL210W"
/db_xref="GeneID:855511"
mRNA 250931..251743
/gene="MER1"
/locus_tag="YNL210W"
/product="Mer1p"
/transcript_id="NM_001183048.1"
/db_xref="GI:296147566"
/db_xref="GeneID:855511"
CDS 250931..251743
/gene="MER1"
/locus_tag="YNL210W"
/note="Protein with RNA-binding motifs required for
meiosis-specific mRNA splicing; required for chromosome
pairing and meiotic recombination; Mer1p regulon embraces
four essential meiotic pre-mRNAs: REC107, HFM1, AMA1 and
SPO22"
/codon_start=1
/product="Mer1p"
/protein_id="NP_014189.1"
/db_xref="GI:6324119"
/db_xref="SGD:S000005154"
/db_xref="GeneID:855511"
/translation="MSNQHSPQPFCLDTKLVKLLEELQEGKQFNNKNIFPEKALYLKL
ALDYSFFRKNLLEFCVHLDKIKGVIRPNYDTIYILCLLEVDLLNLVFTDNILEICLPR
FVSREDLRVFNNTFYTYHDNRLRILQEDFSQLFKKIKTKASVLCFTVEEIFLTNQEIL
PQNSTVAELQKSTNKVQTNGPQRHDFIVTLEIKLNKTQITFLIGAKGTRIESLREKSG
ASIKIIPISDKMTAHERNHPESVQQTILISGDLYSIALAVTSIESALITLDL"
gene 252059..253900
/gene="SSB2"
/locus_tag="YNL209W"
/gene_synonym="YG103"
/db_xref="GeneID:855512"
mRNA 252059..253900
/gene="SSB2"
/locus_tag="YNL209W"
/gene_synonym="YG103"
/product="Ssb2p"
/transcript_id="NM_001183047.1"
/db_xref="GI:296147567"
/db_xref="GeneID:855512"
CDS 252059..253900
/gene="SSB2"
/locus_tag="YNL209W"
/gene_synonym="YG103"
/note="Cytoplasmic ATPase that is a ribosome-associated
molecular chaperone, functions with J-protein partner
Zuo1p; may be involved in the folding of newly-synthesized
polypeptide chains; member of the HSP70 family; homolog of
SSB1"
/codon_start=1
/product="Hsp70 family ATPase SSB2"
/protein_id="NP_014190.1"
/db_xref="GI:6324120"
/db_xref="SGD:S000005153"
/db_xref="GeneID:855512"
/translation="MAEGVFQGAIGIDLGTTYSCVATYESSVEIIANEQGNRVTPSFV
AFTPQERLIGDAAKNQAALNPRNTVFDAKRLIGRRFDDESVQKDMKTWPFKVIDVDGN
PVIEVQYLEETKTFSPQEISAMVLTKMKEIAEAKIGKKVEKAVITVPAYFNDAQRQAT
KDAGAISGLNVLRIINEPTAAAIAYGLGAGKSEKERHVLIFDLGGGTFDVSLLHIAGG
VYTVKSTSGNTHLGGQDFDTNLLEHFKAEFKKKTGLDISDDARALRRLRTAAERAKRT
LSSVTQTTVEVDSLFDGEDFESSLTRARFEDLNAALFKSTLEPVEQVLKDAKISKSQI
DEVVLVGGSTRIPKVQKLLSDFFDGKQLEKSINPDEAVAYGAAVQGAILTGQSTSDET
KDLLLLDVAPLSLGVGMQGDIFGIVVPRNTTVPTIKRRTFTTVSDNQTTVQFPVYQGE
RVNCKENTLLGEFDLKNIPMMPAGEPVLEAIFEVDANGILKVTAVEKSTGKSSNITIS
NAVGRLSSEEIEKMVNQAEEFKAADEAFAKKHEARQRLESYVASIEQTVTDPVLSSKL
KRGSKSKIEAALSDALAALQIEDPSADELRKAEVGLKRVVTKAMSSR"
gene 254418..255017
/locus_tag="YNL208W"
/db_xref="GeneID:855513"
mRNA 254418..255017
/locus_tag="YNL208W"
/product="hypothetical protein"
/transcript_id="NM_001183046.1"
/db_xref="GI:296147568"
/db_xref="GeneID:855513"
CDS 254418..255017
/locus_tag="YNL208W"
/note="hypothetical protein; may interact with ribosomes,
based on co-purification experiments; authentic,
non-tagged protein is detected in purified mitochondria in
high-throughput studies; potential orthologs found in
other fungi"
/codon_start=1
/product="hypothetical protein"
/protein_id="NP_014191.2"
/db_xref="GI:42742305"
/db_xref="SGD:S000005152"
/db_xref="GeneID:855513"
/translation="MSANEFYSSGQQGQYNQQNNQERTGAPNNGQYGADNGNPNGERG
LFSTIVGGSAGAYAGSKVSNNHSKLSGVLGAIGGAFLANKISDERKEHKQQEQYGNSN
FGGAPQGGHNNHHRQDNNNNNGGFGGPGGPGGQGFGRQGPQGFGGPGPQEFGGPGGQG
FGGPNPQEFGGPGGQGFGGPNPQEFGGQGRQGFNGGSRW"
gene 255353..256630
/gene="RIO2"
/locus_tag="YNL207W"
/db_xref="GeneID:855514"
mRNA 255353..256630
/gene="RIO2"
/locus_tag="YNL207W"
/product="Rio2p"
/transcript_id="NM_001183045.1"
/db_xref="GI:296147569"
/db_xref="GeneID:855514"
CDS 255353..256630
/gene="RIO2"
/locus_tag="YNL207W"
/EC_number="2.7.11.1"
/note="Essential serine kinase involved in the processing
of the 20S pre-rRNA into mature 18S rRNA; has similarity
to Rio1p"
/codon_start=1
/product="Rio2p"
/protein_id="NP_014192.1"
/db_xref="GI:6324122"
/db_xref="SGD:S000005151"
/db_xref="GeneID:855514"
/translation="MKLDTSHMRYLTTDDFRVLQAVEQGSRSHEVVPTPLIHQISGMR
SQSGTNRAISDLAKLSLISKMRNVKYDGYRLTYNGIDYLALKTMLNRDTVYSVGNTIG
VGKESDIYKVSDKNGNPRVMKIHRLGRTSFHSVRNNRDYLKKSNQGANWMHLSRLAAN
KEYQFMSMLYSKGFKVPEPFDNSRHIVVMELIEGYPMRRLRKHKNIPKLYSDLMCFIV
DLANSGLIHCDFNEFNIMIKDKLEDENDCGFVVIDFPQCISIQHQDADYYFQRDVDCI
RRFFKKKLKYEPKPDSSMLDTEGFGDGYKYAYPDFKRDVKRTDNLDELVQASGFSKKH
PGDRGLETAVESMRNAVYNSDDDMSNDEAEEENGEGDYSEEDEYYDSELDNESSEDDS
EDAQEEENERIIEALSSGVENLKMDKLGNYILE"
gene complement(256788..258155)
/gene="RTT106"
/locus_tag="YNL206C"
/db_xref="GeneID:855515"
mRNA complement(256788..258155)
/gene="RTT106"
/locus_tag="YNL206C"
/product="Rtt106p"
/transcript_id="NM_001183044.1"
/db_xref="GI:296147570"
/db_xref="GeneID:855515"
CDS complement(256788..258155)
/gene="RTT106"
/locus_tag="YNL206C"
/note="Histone chaperone, involved in regulation of
chromatin structure in both transcribed and silenced
chromosomal regions; affects transcriptional elongation;
has a role in regulation of Ty1 transposition"
/codon_start=1
/product="Rtt106p"
/protein_id="NP_014193.1"
/db_xref="GI:6324123"
/db_xref="SGD:S000005150"
/db_xref="GeneID:855515"
/translation="MSKLFLDELPESLSRKIGTVVRVLPSSLEIFEELYKYALNENSN
DRSGRHKKPRIDVSSDLLKTDEISETNTIFKLEGVSVLSPLRKKLDLVFYLSNVDGSP
VITLLKGNDRELSIYQLNKNIKMASFLPVPEKPNLIYLFMTYTSCEDNKFSEPVVMTL
NKENTLNQFKNLGLLDSNVTDFEKCVEYIRKQAILTGFKISNPFVNSTLVDTDAEKIN
SFHLQCHRGTKEGTLYFLPDHIIFGFKKPILLFDASDIESITYSSITRLTFNASLVTK
DGEKYEFSMIDQTEYAKIDDYVKRKQMKDKSMSEELKAKSKSKGQATDGTADQPSILQ
EATRQMQDEKKAGVFSDDDEENDQNFEAESDLSDGSGQESSDGAEDGEEAEEDDEEDD
EEEDKKGQSALNRDNSFASINGQPEQELQYKEFKEPLELEDIPIEIDNDDDEDDEDGS
GVEYD"
gene complement(258375..259277)
/gene="SPS18"
/locus_tag="YNL204C"
/gene_synonym="SPX18"
/db_xref="GeneID:855517"
mRNA complement(258375..259277)
/gene="SPS18"
/locus_tag="YNL204C"
/gene_synonym="SPX18"
/product="Sps18p"
/transcript_id="NM_001183042.1"
/db_xref="GI:296147571"
/db_xref="GeneID:855517"
CDS complement(258375..259277)
/gene="SPS18"
/locus_tag="YNL204C"
/gene_synonym="SPX18"
/note="hypothetical protein, contains a putative
zinc-binding domain; expressed during sporulation"
/codon_start=1
/product="Sps18p"
/protein_id="NP_014195.1"
/db_xref="GI:6324125"
/db_xref="SGD:S000005148"
/db_xref="GeneID:855517"
/translation="MRLFENSKDMENRKRLLRAKKAAGNNNCFECKSVNPQFVSCSFG
IFICVNCANLLRGMGTNIFCVKSITMDNFEEKDVRRVEKSGNNRFGSFLSKNGILQNG
IPLREKYDNLFAKSYKRRLANEVRSNDINRNMYLGFNNFQQYTNGATSQIRDRTLREI
SNNSNASEGAEFVLPEKVLGSDNFQDCERFPACLSSERNLDENNVTSATSTLTIEKFQ
NDPIGTISRSWQLLSDALYKSYEDFKGSVVQPTIENIQQRNLPNDIKRSFVHFNEKLH
ETPHLPSPVFSCFTGGDILPPEFN"
gene 259578..260456
/gene="SPS19"
/locus_tag="YNL202W"
/gene_synonym="SPX19"
/db_xref="GeneID:855518"
mRNA 259578..260456
/gene="SPS19"
/locus_tag="YNL202W"
/gene_synonym="SPX19"
/product="Sps19p"
/transcript_id="NM_001183040.1"
/db_xref="GI:296147572"
/db_xref="GeneID:855518"
CDS 259578..260456
/gene="SPS19"
/locus_tag="YNL202W"
/gene_synonym="SPX19"
/EC_number="1.3.1.34"
/note="Peroxisomal 2,4-dienoyl-CoA reductase, auxiliary
enzyme of fatty acid beta-oxidation; homodimeric enzyme
required for growth and sporulation on petroselineate
medium; expression induced during late sporulation and in
the presence of oleate"
/codon_start=1
/product="Sps19p"
/protein_id="NP_014197.2"
/db_xref="GI:99030931"
/db_xref="SGD:S000005146"
/db_xref="GeneID:855518"
/translation="MNTANTLDGKFVTEGSWRPDLFKGKVAFVTGGAGTICRVQTEAL
VLLGCKAAIVGRDQERTEQAAKGISQLAKDKDAVLAIANVDVRNFEQVENAVKKTVEK
FGKIDFVIAGAAGNFVCDFANLSPNAFKSVVDIDLLGSFNTAKACLKELKKSKGSILF
VSATFHYYGVPFQGHVGAAKAGIDALAKNLAVELGPLGIRSNCIAPGAIDNTEGLKRL
AGKKYKEKALAKIPLQRLGSTRDIAESTVYIFSPAASYVTGTVLVVDGGMWHLGTYFG
HELYPEALIKSMTSKL"
gene complement(260627..263203)
/gene="PSY2"
/locus_tag="YNL201C"
/db_xref="GeneID:855520"
mRNA complement(260627..263203)
/gene="PSY2"
/locus_tag="YNL201C"
/product="Psy2p"
/transcript_id="NM_001183039.1"
/db_xref="GI:296147573"
/db_xref="GeneID:855520"
CDS complement(260627..263203)
/gene="PSY2"
/locus_tag="YNL201C"
/note="Subunit of protein phosphatase PP4 complex; active
complex is composed of catalytic subunit Pph3p and Psy2p,
with Psy4p apparently providing additional substrate
specificity in some cases; regulates recovery from the DNA
damage checkpoint and also the gene conversion- and
single-strand annealing-mediated pathways of meiotic
double-strand break repair; Pph3p and Psy2p localize to
foci on meiotic chromosomes; putative homolog of mammalian
R3"
/codon_start=1
/product="Psy2p"
/protein_id="NP_014198.1"
/db_xref="GI:6324128"
/db_xref="SGD:S000005145"
/db_xref="GeneID:855520"
/translation="MSLPGTPTTSPTPMDEDTEQAVSVNTEPKRVKVYILENNEWKDT
GTGFCIGEVDEGKFAYLVVSDEDSPTETLLKSKLEGNIEYQRQEETLIVWKDLGGKDI
ALSFEESMGCDTLCEFIVHVQRNIESNISLVTVKSSDNGLGSVHDIITGPVTLPSNDQ
QQNSQTLLEALKILNENTSFDFLKNETIEFILQSNYIDTLISHFHKAEEEKIPKDLFL
LSNIIKTLILYNKRDILESMVEDDRIMGIVGILEYDTEYPTSKANHRKYLGSKGPNFK
EVIPLENEDLKIIMKKCFRLQFLKDVVLVRFLDDHNFNLISEIVMDLETCIIDFLQVG
TFLDRLIELYDTKTLPESSSEKEKFVQKRKDGIRLLQQCVQMSINLDAVDRSKFYKTL
VRKGLFKVLDYAFHMETDSNVRILATDTIITIIEHDILLIHNVQNEDSFKRQHKSAPD
DKSSHRKYPQDYSSSTDSKLLLILSTILLSDRSPGLREQVVQALNTLLHPEGCVGNGE
GSYDLMGRSNYEAKNTSEDFPSFSYGLNSDSINLNNYHYSSDEMNNLEPESESEFQVM
EYFANFYNKIAPILFGPLIKKDITTEMAEIDGQIEKVTKDDLLLIHLVKLVSFVCTEH
DRVLSRRFILENGILDSVSKLIGGNHMMQLRLTAVRCIKNLMCLDDKYYHRYMISKNL
YAPVFKLFQENIDKNNLANSCIQDFFRIIITECRAYQSDGHNRKEKTNGSYDGNGNDV
KTNVNNNRTNFTILNKYLVQTYGDVLRKATDIPFIQDMLETGEENQPDHSSFENSIEG
GNDISVNMSTDGFASNHLEDIDIKNVKRLHSEIEHFENDPHYSGDQLAFKKSVDQMNA
ST"
gene complement(263713..264453)
/locus_tag="YNL200C"
/db_xref="GeneID:855521"
mRNA complement(263713..264453)
/locus_tag="YNL200C"
/product="NADHX epimerase"
/transcript_id="NM_001183038.1"
/db_xref="GI:296147574"
/db_xref="GeneID:855521"
CDS complement(263713..264453)
/locus_tag="YNL200C"
/note="NADHX epimerase; catalyzes isomerization of (R)-
and (S)-NADHX; homologous to AIBP in mammals and the N-
terminal domain of YjeF in E.coli; enzyme is widespread in
eukaryotes, prokaryotes and archaea; the authentic,
non-tagged protein is detected in highly purified
mitochondria in high-throughput studies"
/codon_start=1
/product="NADHX epimerase"
/protein_id="NP_014199.1"
/db_xref="GI:6324129"
/db_xref="SGD:S000005144"
/db_xref="GeneID:855521"
/translation="MSTLKVVSSKLAAEIDKELMGPQIGFTLQQLMELAGFSVAQAVC
RQFPLRGKTETEKGKHVFVIAGPGNNGGDGLVCARHLKLFGYNPVVFYPKRSERTEFY
KQLVHQLNFFKVPVLSQDEGNWLEYLKPEKTLCIVDAIFGFSFKPPMREPFKGIVEEL
CKVQNIIPIVSVDVPTGWDVDKGPISQPSINPAVLVSLTVPKPCSSHIRENQTTHYVG
GRFIPRDFANKFGFEPFGYESTDQILKL"
gene complement(264926..266530)
/gene="GCR2"
/locus_tag="YNL199C"
/db_xref="GeneID:855522"
mRNA complement(264926..266530)
/gene="GCR2"
/locus_tag="YNL199C"
/product="Gcr2p"
/transcript_id="NM_001183037.1"
/db_xref="GI:296147575"
/db_xref="GeneID:855522"
CDS complement(264926..266530)
/gene="GCR2"
/locus_tag="YNL199C"
/note="Transcriptional activator of genes involved in
glycolysis; interacts and functions with the DNA-binding
protein Gcr1p"
/codon_start=1
/product="Gcr2p"
/protein_id="NP_014200.1"
/db_xref="GI:6324130"
/db_xref="SGD:S000005143"
/db_xref="GeneID:855522"
/translation="MHHQTKLDVFIIRAYNLLSNESVISGASLQSVTNSPQTTTNTPS
GMVNGAVGTGIANPTGLMGSDSTPNIDEIITSTGSNALTKTNSDSANGTPNGNSSSTS
AISNASNPATTGNNASSSATSNGIYTQAQYSQLFAKISKLYNATLSSGSIDDRSTSPK
SAIELYQRFQQMIKELELSFDASPYAKYFRRLDGRLWQIKTDSELENDELWRLVSMSI
FTVFDPQTGQILTQGRRKGNSLNTSTKGSPSDLQGINNGNNNGNNGNIGNGSNIKNYG
NKNMPNNRTKKRGTRVAKNAKNGKNNKNSNKERNGITDTSAFSNTTISNPGTNMLFDP
SLSQQLQKRLQTLSQDVNSRSLTGYYTQPTSPGSGGFEFGLSHADLNPNASSNTMGYN
TMSNNGSHSWKRRSLGSLDVNTLDDEAVEELLQLTNTSKRQRPMTTAAEGALINDGPD
TNLNANNTQMKVDLNPSNSMGPIDTEAVIRPLKEAYDAIISEKGQRIVQLERELELQR
QETQWLRKMLIEDMGCVRSMLRDLQR"
gene complement(267608..269593)
/gene="WHI3"
/locus_tag="YNL197C"
/db_xref="GeneID:855524"
mRNA complement(267608..269593)
/gene="WHI3"
/locus_tag="YNL197C"
/product="Whi3p"
/transcript_id="NM_001183035.1"
/db_xref="GI:296147576"
/db_xref="GeneID:855524"
CDS complement(267608..269593)
/gene="WHI3"
/locus_tag="YNL197C"
/note="RNA binding protein that sequesters CLN3 mRNA in
cytoplasmic foci; cytoplasmic retention factor for Cdc28p
and associated cyclins; regulates cell fate and
dose-dependently regulates the critical cell size required
for passage through Start"
/codon_start=1
/product="Whi3p"
/protein_id="NP_014202.1"
/db_xref="GI:6324132"
/db_xref="SGD:S000005141"
/db_xref="GeneID:855524"
/translation="MQSSVYFDQTGSFASSSDNVVSSTTNTHNISPSHRSSLNLNTTS
HPHEASGRGSASGELYLNDTNSPLAISSMLNTLALGSMPQDIASSNISNHDNNIKGSY
SLKLSNVAKDITLRECYAIFALAEGVKSIELQKKNSSSSITSASLEDENDIFIIARFE
LLNLAINYAVILNSKNELFGPSFPNKTTVEIIDDTTKNLVSFPSSAIFNDTSRLNKSN
SGMKRPSLLSQRSRFSFSDPFSNDSPLSQQQSQQQQQQPQQPQQHSTQKHSPQQCNQQ
QVNSSIPLSSQGQVIGLHSNHSHQDLSVESTIQTSDIGKSFLLRDNTEINEKIWGTSG
IPSSINGYMSTPQPSTPTLEWGNTSASQHGSSFFLPSAASTAIAPTNSNTSANANASS
NNGASNNGANQALSASSQQPMMQIGNTINTSLTSSNSLPPYGLMSSQSQHISNMVNTS
DMNITPQKQNRFMQQPQPEHMYPVNQSNTPQKVPPARLSSSRNSHKNNSTTSLSSNIT
GSASISQADLSLLARIPPPANPADQNPPCNTLYVGNLPSDATEQELRQLFSGQEGFRR
LSFRNKNTTSNGHSHGPMCFVEFDDVSFATRALAELYGRQLPRSTVSSKGGIRLSFSK
NPLGVRGPNSRRGGSGNPNPNVNMLSSYNSNVGHIKN"
gene complement(270275..271171)
/gene="SLZ1"
/locus_tag="YNL196C"
/db_xref="GeneID:855525"
mRNA complement(270275..271171)
/gene="SLZ1"
/locus_tag="YNL196C"
/product="Slz1p"
/transcript_id="NM_001183034.1"
/db_xref="GI:296147577"
/db_xref="GeneID:855525"
CDS complement(270275..271171)
/gene="SLZ1"
/locus_tag="YNL196C"
/note="Sporulation-specific protein with a leucine zipper
motif"
/codon_start=1
/product="Slz1p"
/protein_id="NP_014203.1"
/db_xref="GI:6324133"
/db_xref="SGD:S000005140"
/db_xref="GeneID:855525"
/translation="MMNKVDQIIGYKKYEVKLPKDRQVKKNKSKGGNVDQIDTKREKD
KMRAFGEERKKFLDKMAKNKKKNTSRKDREKPKEVEKENYKREDKRLKEQKKLSLAKE
FRFKEPNSEAINQNTAAENGKPKPQTGLDFDIDHQTVSKIMIDQAIQTSSPLNVQLTE
LFNDNVLDVSKDSQFVLQDMEFTSWERRWSNCSTTSNATTVSSVPDPKYNINYNDITS
FNSVALITEDLNISASSNGLHERGKKLLQQEMEYSNKVKNVTIGLERLCMDEKPVPDA
GITMQQASRWSEFPTCCDQAAI"
gene complement(271523..272308)
/locus_tag="YNL195C"
/db_xref="GeneID:855526"
mRNA complement(271523..272308)
/locus_tag="YNL195C"
/product="hypothetical protein"
/transcript_id="NM_001183033.1"
/db_xref="GI:296147578"
/db_xref="GeneID:855526"
CDS complement(271523..272308)
/locus_tag="YNL195C"
/note="hypothetical protein; shares a promoter with
YNL194C; the authentic, non-tagged protein is detected in
highly purified mitochondria in high-throughput studies"
/codon_start=1
/product="hypothetical protein"
/protein_id="NP_014204.2"
/db_xref="GI:42742306"
/db_xref="SGD:S000005139"
/db_xref="GeneID:855526"
/translation="MLGLGQSAQAYASDDALNMNQAKDKTYSVPGCGRASDLKYPHRD
GHSSSHEQRSGILPTECPGPTLNTGAGSIGIPGCGKVTNRVVSDYNKNARSTLANFDS
SKMTEARMNSKNVPIGCQDTSDPHFNGPIDQHVPGAGSPQSQPHHIDAWNSVSSRRAD
NNNQDMMDPQTASSDRYNEKMMREENSGVSASSYTTKVQGYPASIPSFNQETEEKETY
AYGVGDRHNVPRNQIMDETNPSANVLNATDHSISHPENKVLHK"
gene complement(272710..273615)
/locus_tag="YNL194C"
/db_xref="GeneID:855527"
mRNA complement(272710..273615)
/locus_tag="YNL194C"
/product="hypothetical protein"
/transcript_id="NM_001183032.1"
/db_xref="GI:296147579"
/db_xref="GeneID:855527"
CDS complement(272710..273615)
/locus_tag="YNL194C"
/note="Integral membrane protein required for sporulation
and plasma membrane sphingolipid content; has sequence
similarity to SUR7 and FMP45; GFP-fusion protein is
induced in response to the DNA-damaging agent MMS"
/codon_start=1
/product="hypothetical protein"
/protein_id="NP_014205.1"
/db_xref="GI:6324135"
/db_xref="SGD:S000005138"
/db_xref="GeneID:855527"
/translation="MSYKKFVYFINLFFLLGATLLTFFLILAGGRTTGVLKNFYWFQA
STSGFNSAPSVTRWYNYNWCGWESRGIAVNCSSKMAAQPFSPRDNFGSSPLMPSTFLN
NRNAYYYLSRVGWAMLLIGLFFLLITLVSVIASLIRYNRRTAALATAMSWITLFFITL
SACLYTGCYAKAVKAFHHENRDARLGPKNFGLIWTTVFLLIVNAICCTIMVATHKRNE
YIYDRSFASTKTVDSQTPTPVPTNGGIPSSVPVTEVQQSQSHQNHRFFKKLRTKKRTV
TSAGDEPDRVQEERVYTEQNVPVVS"
gene 274368..276044
/locus_tag="YNL193W"
/db_xref="GeneID:855528"
mRNA 274368..276044
/locus_tag="YNL193W"
/product="hypothetical protein"
/transcript_id="NM_001183031.2"
/db_xref="GI:330443695"
/db_xref="GeneID:855528"
CDS 274368..276044
/locus_tag="YNL193W"
/note="hypothetical protein; exhibits a two-hybrid
interaction with Yhr151cp in a large-scale analysis"
/codon_start=1
/product="hypothetical protein"
/protein_id="NP_014206.2"
/db_xref="GI:330443696"
/db_xref="SGD:S000005137"
/db_xref="GeneID:855528"
/translation="MGPPKNFKHFSKSNKHKKEQKALITQEDFYLAAIDCEEQADRWL
LSDIKKCLRFYLKALEHYENGLTALDSTQEGKYNIYYNETRLFLQIYTDYLANNGYIN
ILQYVKMDDMPDLSNLVLSLPQIIQRFEIVYETFPEQRTWDLQFNLLTCYLTLIESLD
DTVSPTVAMEGADILTLTNKYIEIFQHLVNYLLQELQNWSENAEQDSDDTDTELQRDT
LDEDAMQVTRDGSGIRTNGPVQPPAEVMDVSEQVTPSSLTEVLANSLKFNHALMELVI
ESKISIEKNVETKILNPIQINFLEDTTNKFYLQLRDIIDSISAAIPLDLKEIGLAKTL
IEGLNIISSGTFESLQDFVLQTVSFTDLLDEKDVQGKIDLSLIRVDIVEFAILCLNDY
SSDASWKLSGLLTKVLTEARTLLTDYRNQILFLKNQTLNEQLSHVVFQLCDVLVNSSD
NELRRYAIKESTEKSQKTPGGAHTLNILMKNANVFLNNAVAISSKQCGLQETIIDKLK
RNYIHNQAKERLLFLQRLEQKSNEDDGTSASPTAMTFDMPPEHPFYSHYR"
gene 276502..279897
/gene="CHS1"
/locus_tag="YNL192W"
/gene_synonym="USA4"
/db_xref="GeneID:855529"
mRNA 276502..279897
/gene="CHS1"
/locus_tag="YNL192W"
/gene_synonym="USA4"
/product="chitin synthase CHS1"
/transcript_id="NM_001183030.2"
/db_xref="GI:330443697"
/db_xref="GeneID:855529"
CDS 276502..279897
/gene="CHS1"
/locus_tag="YNL192W"
/gene_synonym="USA4"
/EC_number="2.4.1.16"
/note="Chitin synthase I, requires activation from
zymogenic form in order to catalyze the transfer of
N-acetylglucosamine (GlcNAc) to chitin; required for
repairing the chitin septum during cytokinesis;
transcription activated by mating factor"
/codon_start=1
/product="chitin synthase CHS1"
/protein_id="NP_014207.2"
/db_xref="GI:330443698"
/db_xref="SGD:S000005136"
/db_xref="GeneID:855529"
/translation="MSDQNNRSRNEYHSNRKNEPSYELQNAHSGLFHSSNEELTNRNQ
RYTNQNASMGSFTPVQSLQFPEQSQQTNMLYNGDDGNNNTINDNERDIYGGFVNHHRQ
RPPPATAEYNDVFNTNSQQLPSEHQYNNVPSYPLPSINVIQTTPELIHNGSQTMATPI
ERPFFNENDYYYNNRNSRTSPSIASSSDGYADQEARPILEQPNNNMNSGNIPQYHDQP
FGYNNGYHGLQAKDYYDDPEGGYIDQRGDDYQINSYLGRNGEMVDPYDYENSLRHMTP
MERREYLHDDSRPVNDGKEELDSVKSGYSHRDLGEYDKDDFSRDDEYDDLNTIDKLQF
QANGVPASSSVSSIGSKESDIIVSNDNLTANRALKRSGTEIRKFKLWNGNFVFDSPIS
KTLLDQYATTTENANTLPNEFKFMRYQAVTCEPNQLAEKNFTVRQLKYLTPRETELML
VVTMYNEDHILLGRTLKGIMDNVKYMVKKKNSSTWGPDAWKKIVVCIISDGRSKINER
SLALLSSLGCYQDGFAKDEINEKKVAMHVYEHTTMINITNISESEVSLECNQGTVPIQ
LLFCLKEQNQKKINSHRWAFEGFAELLRPNIVTLLDAGTMPGKDSIYQLWREFRNPNV
GGACGEIRTDLGKRFVKLLNPLVASQNFEYKMSNILDKTTESNFGFITVLPGAFSAYR
FEAVRGQPLQKYFYGEIMENEGFHFFSSNMYLAEDRILCFEVVTKKNCNWILKYCRSS
YASTDVPERVPEFILQRRRWLNGSFFASVYSFCHFYRVWSSGHNIGRKLLLTVEFFYL
FFNTLISWFSLSSFFLVFRILTVSIALAYHSAFNVLSVIFLWLYGICTLSTFILSLGN
KPKSTEKFYVLTCVIFAVMMIYMIFCSIFMSVKSFQNILKNDTISFEGLITTEAFRDI
VISLGSTYCLYLISSIIYLQPWHMLTSFIQYILLSPSYINVLNIYAFCNVHDLSWGTK
GAMANPLGKINTTEDGTFKMEVLVSSSEIQANYDKYLKVLNDFDPKSESRPTEPSYDE
KKTGYYANVRSLVIIFWVITNFIIVAVVLETGGIADYIAMKSISTDDTLETAKKAEIP
LMTSKASIYFNVILWLVALSALIRFIGCSIYMIVRFFKKVTFR"
rep_origin 279880..280112
/note="ARS1414;
ARS activated in mid-S phase"
/db_xref="SGD:S000077376"
gene 280432..281505
/gene="DUG3"
/locus_tag="YNL191W"
/db_xref="GeneID:855530"
mRNA 280432..281505
/gene="DUG3"
/locus_tag="YNL191W"
/product="glutamine amidotransferase subunit DUG3"
/transcript_id="NM_001183029.1"
/db_xref="GI:296147582"
/db_xref="GeneID:855530"
CDS 280432..281505
/gene="DUG3"
/locus_tag="YNL191W"
/note="Component of glutamine amidotransferase (GATase
II); forms a complex with Dug2p to degrade glutathione
(GSH) and other peptides containing a gamma-glu-X bond in
an alternative pathway to GSH degradation by
gamma-glutamyl transpeptidase (Ecm38p)"
/codon_start=1
/product="glutamine amidotransferase subunit DUG3"
/protein_id="NP_014208.1"
/db_xref="GI:6324138"
/db_xref="SGD:S000005135"
/db_xref="GeneID:855530"
/translation="MCRFLIFKGKQPIRLSHLLTRPAHSIINQSFDSRLRLDRRRPMN
GDGFGVAYYPLDTELSEDGPCLFKAITPAWNNQNLSTLAEKTKSDLVFAHVRASTYGV
LSETNCHPFTYHSLCFMHNGGISNFKGIKRKLLNHIKDEYLNFIQGSTDSECAFALFL
DTLDKLGYDPKKQDGDFGNVALRKAMLRTIDYIRDWTKEANKDEAHVEPSLLNFAVTD
GSTVVVSRYITSKTDEAASLHFSCGSSFVETSPGEYRVERLDRNQDVIMVASEPLTFE
RGDWTAVPTNSILTIKKQTILLHPIIDEYYQEDPLYLRSSTLAESKGLMGSIPLAKAV
EKNVPPLEREGRTRPPTAVAHIA"
gene 282395..283009
/locus_tag="YNL190W"
/db_xref="GeneID:855531"
mRNA 282395..283009
/locus_tag="YNL190W"
/product="hypothetical protein"
/transcript_id="NM_001183028.1"
/db_xref="GI:296147583"
/db_xref="GeneID:855531"
CDS 282395..283009
/locus_tag="YNL190W"
/note="Hydrophilin essential in dessication-rehydration
process; cell wall protein; contains a putative
GPI-attachment site"
/codon_start=1
/product="hypothetical protein"
/protein_id="NP_014209.1"
/db_xref="GI:6324139"
/db_xref="SGD:S000005134"
/db_xref="GeneID:855531"
/translation="MKFSSVTAITLATVATVATAKKGEHDFTTTLTLSSDGSLTTTTS
THTTHKYGKFNKTSKSKTPNHTGTHKYGKFNKTSKSKTPNHTGTHKYGKFNKTSKSKT
PNHTGTHKYGKFNKTSKSKTPNHTGTHKYGKFNKTSKSKTPNHTGTHKYGKFNKTKHD
TTTYGPGEKARKNNAAPGPSNFNSIKLFGVTAGSAAVAGALLLL"
gene 284260..285888
/gene="SRP1"
/locus_tag="YNL189W"
/gene_synonym="KAP60; SCM1"
/db_xref="GeneID:855532"
mRNA 284260..285888
/gene="SRP1"
/locus_tag="YNL189W"
/gene_synonym="KAP60; SCM1"
/product="Srp1p"
/transcript_id="NM_001183027.1"
/db_xref="GI:296147584"
/db_xref="GeneID:855532"
CDS 284260..285888
/gene="SRP1"
/locus_tag="YNL189W"
/gene_synonym="KAP60; SCM1"
/note="Karyopherin alpha homolog, forms a dimer with
karyopherin beta Kap95p to mediate import of nuclear
proteins, binds the nuclear localization signal of the
substrate during import; may also play a role in
regulation of protein degradation"
/codon_start=1
/product="Srp1p"
/protein_id="NP_014210.1"
/db_xref="GI:6324140"
/db_xref="SGD:S000005133"
/db_xref="GeneID:855532"
/translation="MDNGTDSSTSKFVPEYRRTNFKNKGRFSADELRRRRDTQQVELR
KAKRDEALAKRRNFIPPTDGADSDEEDESSVSADQQFYSQLQQELPQMTQQLNSDDMQ
EQLSATVKFRQILSREHRPPIDVVIQAGVVPRLVEFMRENQPEMLQLEAAWALTNIAS
GTSAQTKVVVDADAVPLFIQLLYTGSVEVKEQAIWALGNVAGDSTDYRDYVLQCNAME
PILGLFNSNKPSLIRTATWTLSNLCRGKKPQPDWSVVSQALPTLAKLIYSMDTETLVD
ACWAISYLSDGPQEAIQAVIDVRIPKRLVELLSHESTLVQTPALRAVGNIVTGNDLQT
QVVINAGVLPALRLLLSSPKENIKKEACWTISNITAGNTEQIQAVIDANLIPPLVKLL
EVAEYKTKKEACWAISNASSGGLQRPDIIRYLVSQGCIKPLCDLLEIADNRIIEVTLD
ALENILKMGEADKEARGLNINENADFIEKAGGMEKIFNCQQNENDKIYEKAYKIIETY
FGEEEDAVDETMAPQNAGNTFGFGSNVNQQFNFN"
gene 286308..287609
/gene="KAR1"
/locus_tag="YNL188W"
/db_xref="GeneID:855533"
mRNA 286308..287609
/gene="KAR1"
/locus_tag="YNL188W"
/product="Kar1p"
/transcript_id="NM_001183026.1"
/db_xref="GI:296147585"
/db_xref="GeneID:855533"
CDS 286308..287609
/gene="KAR1"
/locus_tag="YNL188W"
/note="Essential protein involved in karyogamy during
mating and in spindle pole body duplication during
mitosis, localizes to the half-bridge of the spindle pole
body, interacts with Spc72p during karyogamy, also
interacts with Cdc31p"
/codon_start=1
/product="Kar1p"
/protein_id="NP_014211.1"
/db_xref="GI:6324141"
/db_xref="SGD:S000005132"
/db_xref="GeneID:855533"
/translation="MNVTSPKDGNHSFSKKNRFNTNKPRFHKLNEQAQSINLPEDRDS
IVSSNTTSIMTDDAFDYNEGIASRTKNINSDSDRSNDTIKQNNYNKRETGYNPFYNGS
GINQRYTQFRKREFEPTLAENKAEEYISDEDNVKIDEDNIENELQFTPKIKEASILRS
SLLGQRNVLNTRNPKSKESHIKVKPIINNKSSSQRKSSAALRKQLGKPLPLPYLNSPN
SDSTPTLQRKEEVFTDEVLQKKRELIESKWHRLLFHDKKMVEKKLESLREYERKRMPP
RGTDVSSSEQDNSFKISTPTKSYVSLEQKPLPNLSAMNNFNDVTDNKEKEETNNNILK
FQAQRDPLQILQSEIEMHTKKLDTIIELLKDDTDSKEKRKVVTNDNAAPEQMVNKGWR
KNVMMIYKKSGNIMKKYREYFLWTICILILLYCNIYVYYRF"
gene 287994..289067
/gene="SWT21"
/locus_tag="YNL187W"
/db_xref="GeneID:855534"
mRNA 287994..289067
/gene="SWT21"
/locus_tag="YNL187W"
/product="Swt21p"
/transcript_id="NM_001183025.1"
/db_xref="GI:296147586"
/db_xref="GeneID:855534"
CDS 287994..289067
/gene="SWT21"
/locus_tag="YNL187W"
/note="Protein involved in mRNA splicing; contains a
consensus nuclear export signal (NES) sequence similar to
the consensus sequence recognized by Crm1p; interacts
genetically with Prp40p and Tgs1p; contains WD40 repeats"
/codon_start=1
/product="Swt21p"
/protein_id="NP_014212.1"
/db_xref="GI:6324142"
/db_xref="SGD:S000005131"
/db_xref="GeneID:855534"
/translation="MEKKVICQDIFWSCDGTSFVSVHNDFGIRQYLVPEESNTDKLNR
NLLLPFTRFFRNQSIVSCAIDPFYTLYNENSDRLAGDRIVVGGKNFPLQLYSLMDGQC
ILSYDTMNKINGEYETVYSVKIDVESRVYTGSCRNKVAIYDKSRRDAVWMNQSTKKAS
KGRQSIISCFEEQPMGGQALSRGSLLCGSYANEMFQVDCRHQRLERLNYTRTVAGGIV
QILTSDNGRYVYVVRRNSDAISIYDRRNLQHELNVLRLPFRIHHNSAKLKAYIDTAYG
LSMGTPQGTILNWGRDLVEFGGVPSHNSVEDPLITSIPPESEWRTNLDSTIPATVVKN
CPGDPELFALSHGGTISLCRFGG"
gene 289498..291876
/gene="UBP10"
/locus_tag="YNL186W"
/gene_synonym="DOT4"
/db_xref="GeneID:855535"
mRNA 289498..291876
/gene="UBP10"
/locus_tag="YNL186W"
/gene_synonym="DOT4"
/product="Ubp10p"
/transcript_id="NM_001183024.2"
/db_xref="GI:330443699"
/db_xref="GeneID:855535"
CDS 289498..291876
/gene="UBP10"
/locus_tag="YNL186W"
/gene_synonym="DOT4"
/EC_number="3.1.2.15"
/note="Ubiquitin-specific protease, deubiquitinates
Ub-protein moieties; interacts with proteins that function
in rRNA production and ribosome biogenesis; stabilizes
Rpa190p, the largest subunit of RNAP I, by mediating its
deubiquitination; may regulate silencing by acting on
Sir4p; involved in posttranscriptionally regulating Gap1p
and possibly other transporters; localized to the
nucleolus; human USP36 is a functional analog of Ubp10p"
/codon_start=1
/product="Ubp10p"
/protein_id="NP_014213.2"
/db_xref="GI:330443700"
/db_xref="SGD:S000005130"
/db_xref="GeneID:855535"
/translation="MTTQESIKPLVDRILSNPLQFNAAMISNKSNNNDTSAAPENSSY
IVIGKQHNNNSNSTAIAATAESKQIKENNLIDRPNGKKTNTVPKSMAEALLLYTSKND
KDAADATGAKKSAELSTELSTEPPSSSSEDDKVGKEEEEEGEIFHEARDYVEPRKASL
KERDNADKGDGEDIGEDIGEDIGEDIGEDIGEDIGENLGSPLATIDDSSNENEKEKRK
ELSTSISSDDEIEDDEDEDDMDYDSSAMEKELPEEEENDSSSKISEGEKKSLYQDLME
NSTVEVNRYEPVNNTKENGNRNPKGEEEEEEEEELKHKSRSITPPVTISNLSNFYQFN
ENINDRGSLNSTRIVKNWGDKFTNLKPRGLLNHGVTCYTNAAVQAMLHIPSIQHYLFD
ILMGKYDSTISKNSVSYTLAETSKKMWLPVSKNPRKNVSASYINPKHLISRLDDINCM
MSEWQQEDSHEYFMSLMSRLQEDSVPKGHKLIESIIYDIFGGLLKQIVTCKSCGSISK
TEQPFYDLSLHLKGKKKLDPNSDLSSDSINGTSATTSTTTSNAATKPSLSSSSSVNLN
NGSPFAAASDLSSANRRFSIEKSIKDFFNPELIKVDKEQKGYVCEKCHKTTNAVKHSS
ILRAPETLLVHLKKFRFNGTSSSKMKQAVSYPMFLDLTEYCESKELPVKYQLLSVVVH
EGRSLSSGHYIAHCKQPDGSWATYDDEYINIISERDVLKEPNAYYLLYTRLTPKSVPL
PLAKSAMATGNVTSKSKQEQAVNEPNNRPLKINSKKNNRKKWKKNKKRKFTK"
gene complement(292193..292669)
/gene="MRPL19"
/locus_tag="YNL185C"
/db_xref="GeneID:855536"
mRNA complement(292193..292669)
/gene="MRPL19"
/locus_tag="YNL185C"
/product="mitochondrial 54S ribosomal protein YmL19"
/transcript_id="NM_001183023.1"
/db_xref="GI:296147588"
/db_xref="GeneID:855536"
CDS complement(292193..292669)
/gene="MRPL19"
/locus_tag="YNL185C"
/note="Mitochondrial ribosomal protein of the large
subunit"
/codon_start=1
/product="mitochondrial 54S ribosomal protein YmL19"
/protein_id="NP_014214.1"
/db_xref="GI:6324144"
/db_xref="SGD:S000005129"
/db_xref="GeneID:855536"
/translation="MSQAAKNVIVKLIVGAGQAAPSPPVGPALGSKGIKAIDFCKEFN
ARSANYQPGVPVPVLITIKPDRTFTFEMKSPPTGYLLLKALKMDKGHGQPNVGTMLGS
APAKGPTRALGELSLKHVYEIAKIKKSDERHSLLEMEGIVKSIVGVAKSMGIKVVP"
gene complement(292557..292883)
/locus_tag="YNL184C"
/db_xref="GeneID:855537"
mRNA complement(292557..292883)
/locus_tag="YNL184C"
/product="hypothetical protein"
/transcript_id="NM_001270758.1"
/db_xref="GI:398364484"
/db_xref="GeneID:855537"
CDS complement(292557..292883)
/locus_tag="YNL184C"
/note="hypothetical protein; expressed at both mRNA and
protein levels"
/codon_start=1
/product="hypothetical protein"
/protein_id="NP_001257687.1"
/db_xref="GI:398364485"
/db_xref="SGD:S000005128"
/db_xref="GeneID:855537"
/translation="MKRVTLIVLPRRQFPFLKFHSKEALESAVNLQLIRRKKSVNIQI
DSVTFCIYFCLLYFRTLEYHRGTISLHNVTGSKKRDSKANSRSRPSGTITSRGARIGL
QGYKSH"
gene complement(293137..295509)
/gene="NPR1"
/locus_tag="YNL183C"
/db_xref="GeneID:855538"
mRNA complement(293137..295509)
/gene="NPR1"
/locus_tag="YNL183C"
/product="Npr1p"
/transcript_id="NM_001183021.1"
/db_xref="GI:296147589"
/db_xref="GeneID:855538"
CDS complement(293137..295509)
/gene="NPR1"
/locus_tag="YNL183C"
/EC_number="2.7.11.1"
/note="Protein kinase that stabilizes several plasma
membrane amino acid transporters by antagonizing their
ubiquitin-mediated degradation; phosphorylates Aly2p;
negatively regulates Ldb19p-mediated endocytosis through
phosphorylation of Ldb19p, which prevents its association
with the plasma membrane; Npr1p activity is negatively
regulated via phosphorylation by the TOR complex"
/codon_start=1
/product="Npr1p"
/protein_id="NP_014216.1"
/db_xref="GI:6324146"
/db_xref="SGD:S000005127"
/db_xref="GeneID:855538"
/translation="MSSLTRLLQEKRKNETSNSSPRTSADTLTTTPESQSLDLHSRNK
SSSHIGSVSNSSSSDRNRANVPVPGSVTTVTQIYSEEDSSSTAGSSLDDRNQFSSSFL
NANFAHTASFYGTSAQSRDRFGSLINDQGTAGLSSHGGSFAAQNRITSRLSTTSHTSG
RAIPSLSSSIPYSVPNSNKDNNSSNSNSSSLSSSWLETYAGGMPNNISAIDSNVISSP
KVDSVEPRFVISKQKLQKASMDSNNANATQSRSISRSGSFSSQLGNFFFSKNSKESSN
SNSAGMSFSANSNGPSPNIKNPNVTNGSTPIPKPIRARQSSIYSASRQPTGSYTDNFY
GSPSSVHDHLPPSQSVPRSQHSSIGDLKRFFKKSSNSNLSSNSNNVIPNGSPLSSGIA
VPSHSHSSSHFAAGNNSYSTSYNGNGDTIYSHSHGGSGIPFSKRYIKTGADLGAGAGG
SVKLAQRISDNKIFAVKEFRTKFENESKRDYVKKITSEYCIGTTLNHPNIIETIEIVY
ENDRILQVMEYCEYDLFAIVMSNKMSYEEICCCFKQILTGVQYLHSIGLAHRDLKLDN
CVINEKGIVKLIDFGAAVVFSYPFSKNLVEASGIVGSDPYLAPEVCIFAKYDPRPVDI
WSSAIIFACMILKKFPWKIPKLRDNSFKLFCSGRDCDSLSSLVTRTPDPPSYDESHST
EKKKPESSSNNVSDPNNVNIGPQRLLHSLPEETQHIVGRMIDLAPACRGNIEEIMEDP
WIRSIDMCHLVEDGLSFKVVRGEDHHHTQVDQSEAHIAGLEKKKKKQNNQ"
gene complement(295960..297627)
/gene="IPI3"
/locus_tag="YNL182C"
/db_xref="GeneID:855539"
mRNA complement(295960..297627)
/gene="IPI3"
/locus_tag="YNL182C"
/product="Ipi3p"
/transcript_id="NM_001183020.1"
/db_xref="GI:296147590"
/db_xref="GeneID:855539"
CDS complement(295960..297627)
/gene="IPI3"
/locus_tag="YNL182C"
/note="Essential component of the Rix1 complex (Rix1p,
Ipi1p, Ipi3p) that is required for processing of ITS2
sequences from 35S pre-rRNA; highly conserved and contains
WD40 motifs; Rix1 complex associates with Mdn1p in pre-60S
ribosomal particles"
/codon_start=1
/product="Ipi3p"
/protein_id="NP_014217.1"
/db_xref="GI:6324147"
/db_xref="SGD:S000005126"
/db_xref="GeneID:855539"
/translation="MDEQVIFTTNTSGTIASVHSFEQINLRQCSTQSRNSCVQVGNKY
LFIAQAQKALINVYNLSGSFKRESVEQRLPLPEILKCLEVVENDGVQYDRIQGVNHNL
PDFNLPYLLLGSTESGKLYIWELNSGILLNVKPMAHYQSITKIKSILNGKYIITSGND
SRVIIWQTVDLVSASNDDPKPLCILHDHTLPVTDFQVSSSQGKFLSCTDTKLFTVSQD
ATIRCYDLSLIGSKKKQKANENDVSIGKTPVLLATFTTPYSIKSIVLDPADRACYIGT
AEGCFSLNLFYKLKGNAIVNLLQSAGVNTVQKGRVFSLVQRNSLTGGENEDLDALYAM
GQLVCENVLNSNVSCLEISMDGTLLLIGDTEGKVSIAEIYSKQIIRTIQTLTTSQDSV
GEVTNLLTNPYRLERGNLLFEGESKGKQPSNNNGHNFMKIPNLQRVIFDGKNKGHLHD
IWYQIGEPEAETDPNLALPLNDFNAYLEQVKTQESIFSHIGKVSSNVKVIDNKIDATS
SLDSNAAKDEEITELKTNIEALTHAYKELRDMHEKLYEEHQQMLDKQ"
gene 298335..299558
/locus_tag="YNL181W"
/db_xref="GeneID:855540"
mRNA 298335..299558
/locus_tag="YNL181W"
/product="hypothetical protein"
/transcript_id="NM_001183019.2"
/db_xref="GI:330443701"
/db_xref="GeneID:855540"
CDS 298335..299558
/locus_tag="YNL181W"
/note="Putative oxidoreductase; required for cell
viability"
/codon_start=1
/product="hypothetical protein"
/protein_id="NP_014218.2"
/db_xref="GI:330443702"
/db_xref="SGD:S000005125"
/db_xref="GeneID:855540"
/translation="MPLNIIGTALLDGTDKIPYYQTIKKVAPYVLATGAIKYWSRGPS
NTWERKLHGKVYLVTGATSQGMGTSVAYKMAELGAQLIILTREVDEWVTEWCEELREK
TKNELIFVEKCDLSNLWEIRKFATSWLDNSPPRRLDGVIVMSGDMEPWGIPKISLPQR
RSSKDGLELQIATNYVAIFHLLNLLQPSFKAQPPDRDVRIILATCWLQVVGDINIEDP
LWQNAKYKSALKFFASSKLQLGLSMMELQRRLTEDIKNQKTNGAERTGKNVTITMVQP
GTMRSNSLRRVISNGSVVLLIILYCILLYPILWLFTKSGRRGDQSFLYALMTPELEEV
NLKDTKVKYISDCSIVKFARKEFDDEELQKKLFDNTERDILQLEKKVAAKRNANKTGN
QNSKKKSQNKSRKDD"
gene complement(299654..300649)
/gene="RHO5"
/locus_tag="YNL180C"
/gene_synonym="YNS0"
/db_xref="GeneID:855541"
mRNA complement(299654..300649)
/gene="RHO5"
/locus_tag="YNL180C"
/gene_synonym="YNS0"
/product="Rho5p"
/transcript_id="NM_001183018.1"
/db_xref="GI:296147592"
/db_xref="GeneID:855541"
CDS complement(299654..300649)
/gene="RHO5"
/locus_tag="YNL180C"
/gene_synonym="YNS0"
/note="Non-essential small GTPase of the Rho/Rac subfamily
of Ras-like proteins, likely involved in protein kinase C
(Pkc1p)-dependent signal transduction pathway that
controls cell integrity"
/codon_start=1
/product="Rho5p"
/protein_id="NP_014219.1"
/db_xref="GI:6324149"
/db_xref="SGD:S000005124"
/db_xref="GeneID:855541"
/translation="MRSIKCVIIGDGAVGKTSLLISYTTNSFPTDYVPTVFDNYSTTI
AIPNGTASSPLELDNGNDKRGSLSSASSSPSTDRKLYKINLWDTAGQEDYDRLRPLCY
PQTDIFLICFSVSEHASFANVTEKWLPELKQTSNIEGTSLYTKLGKYPILLVGTKSDL
RDDPATQKKLQEANSDYVSQEEIDELVQRCGFMGYTECSAATQAGVREVFEQAVRYAI
YEPESPNQKSANHTLTDELTTATTNTNGDKNIREQKQQPHHNNSTDSTLPKGSLQQEK
EALNIKPTKKGQKDKIHEQSKSKGSKIASNNHHNKQAKPKTRNDKKKKKSKCVIL"
gene 302680..303402
/gene="RPS3"
/locus_tag="YNL178W"
/gene_synonym="SUF14"
/db_xref="GeneID:855543"
mRNA 302680..303402
/gene="RPS3"
/locus_tag="YNL178W"
/gene_synonym="SUF14"
/product="ribosomal 40S subunit protein S3"
/transcript_id="NM_001183016.3"
/db_xref="GI:398364504"
/db_xref="GeneID:855543"
CDS 302680..303402
/gene="RPS3"
/locus_tag="YNL178W"
/gene_synonym="SUF14"
/note="Protein component of the small (40S) ribosomal
subunit, has apurinic/apyrimidinic (AP) endonuclease
activity; essential for viability; homologous to mammalian
ribosomal protein S3 and bacterial S3"
/codon_start=1
/product="ribosomal 40S subunit protein S3"
/protein_id="NP_014221.3"
/db_xref="GI:398364505"
/db_xref="SGD:S000005122"
/db_xref="GeneID:855543"
/translation="MVALISKKRKLVADGVFYAELNEFFTRELAEEGYSGVEVRVTPT
KTEVIIRATRTQDVLGENGRRINELTLLVQKRFKYAPGTIVLYAERVQDRGLSAVAQA
ESMKFKLLNGLAIRRAAYGVVRYVMESGAKGCEVVVSGKLRAARAKAMKFADGFLIHS
GQPVNDFIDTATRHVLMRQGVLGIKVKIMRDPAKSRTGPKALPDAVTIIEPKEEEPIL
APSVKDYRPAEETEAQAEPVEA"
gene complement(303686..304615)
/gene="MRPL22"
/locus_tag="YNL177C"
/db_xref="GeneID:855544"
mRNA complement(303686..304615)
/gene="MRPL22"
/locus_tag="YNL177C"
/product="mitochondrial 54S ribosomal protein YmL22"
/transcript_id="NM_001183015.2"
/db_xref="GI:330443703"
/db_xref="GeneID:855544"
CDS complement(303686..304615)
/gene="MRPL22"
/locus_tag="YNL177C"
/note="Mitochondrial ribosomal protein of the large
subunit"
/codon_start=1
/product="mitochondrial 54S ribosomal protein YmL22"
/protein_id="NP_014222.2"
/db_xref="GI:330443704"
/db_xref="SGD:S000005121"
/db_xref="GeneID:855544"
/translation="MNFHTARISQVGVISRALLSSVSRRWIHVTPISLNNSGGSLFGS
ITENKPKEGKNRGDEDAGSFSNRLAIASDSSGEAPEVNRDSITIENDKLLQQHIISLQ
QPEQLASQSLLSPLKREIYEANCKINGGFYKKDTIVKLPNSSERYKLKLTKREIEVLE
PSVYAQSYRIKSSMKKATLLLRLLGGLDVMKAISQCHFSNKKIAREVAELLQKGVKDG
QKLGLKPEDLYISQIWTGSDGFWRKRVEFKARTRIGIISHPYIHVRCILRTKSVTKRR
LAYEAHLKEQKRAPWVQLGDKPIRGVTGGVYKW"
gene complement(305070..306980)
/gene="TDA7"
/locus_tag="YNL176C"
/db_xref="GeneID:855545"
mRNA complement(305070..306980)
/gene="TDA7"
/locus_tag="YNL176C"
/product="Tda7p"
/transcript_id="NM_001183014.2"
/db_xref="GI:330443705"
/db_xref="GeneID:855545"
CDS complement(305070..306980)
/gene="TDA7"
/locus_tag="YNL176C"
/note="Cell cycle-regulated gene of unknown function,
promoter bound by Fkh2p; null mutant is sensitive to
expression of the top1-T722A allele"
/codon_start=1
/product="Tda7p"
/protein_id="NP_014223.2"
/db_xref="GI:330443706"
/db_xref="SGD:S000005120"
/db_xref="GeneID:855545"
/translation="MNSNSTIGRTTLGESDTISLSFSEPSSSLNSRSTDVVFASTSTL
VPQQGSLTSLPPVSSTATPTYYSTSLTYDETLHTSIDVSSTSTLVSSTDSSSSSEQDT
YSSQYDPATSSYSIITPSMSIFSSTSPMSSSSSITSEWSSLTSTTPTLSSSATSLSSS
WSSLSSPSSLLVSSSLSLSLSSSYSDTKLFSFDSRSSIFSPSTPTVISPSYTYLSSIS
ATSFQISTTSELSSSWFSTISSPSTISNKDTTFPSSSRNTSTSFYSSSLSSTNDFSTI
SKSSKLSPSASSSTVSISTISVPTSSSVSSSSSKVPSNRPSSSSSSDDTTSAYSSTYT
FQSLQSTTSSSIPPTTQTPSTSTISTSPIPTSSQVFNTVAISSSEDSKTIYYFYTQTY
DITDSSTTFVTGLPTTIAVAKSEVTSFSAPSSTITADMSFYQHWLDGSLDNNKNQGTS
KTNTGTIVGSVVGSVGGILICVLVVWFMLVRKRKAKRHFKENDSFCHEIGRRTGFPTT
AQAKEASLQAQDSGSQQRNTETASANNPFSNEFNFKARGNPPPVPPPRNVTAMNGSFQ
NMRSNFMDQENRFSYGSSFTYSSLGSSTQGGFSTLSSNSIRLGRGLDNDISHDERNTV
QNNSQGFLREII"
gene complement(307401..308612)
/gene="NOP13"
/locus_tag="YNL175C"
/db_xref="GeneID:855547"
mRNA complement(307401..308612)
/gene="NOP13"
/locus_tag="YNL175C"
/product="Nop13p"
/transcript_id="NM_001183013.2"
/db_xref="GI:330443707"
/db_xref="GeneID:855547"
CDS complement(307401..308612)
/gene="NOP13"
/locus_tag="YNL175C"
/note="Nucleolar protein found in preribosomal complexes;
contains an RNA recognition motif (RRM); relative
distribution to the nucleolus increases upon DNA
replication stress"
/codon_start=1
/product="Nop13p"
/protein_id="NP_014224.2"
/db_xref="GI:330443708"
/db_xref="SGD:S000005119"
/db_xref="GeneID:855547"
/translation="MSETELSKEDAVTKKDNEEQVKKALLDPTKKRKAEDEIEIDLKS
SIPLSKKQKRLLRRGKVTLEELNAKYNIDPKSIEEYKEDAEKKKSGASEKDAQGEEST
INTPTGDESGEVVKKKKKDENKYGVWIGNLSFDTTKDDLVRFFIAKTKDNEDEKSRVT
EQDITRLSMPRVAAKNSNAMKNKGFCYMFFKNVEQMKAVLELSESHLNGRNMLIKDSE
NYSGRPDKDDLVAMSKNPPSRILFVGNLSFDVTDDLLRKHFQHCGDIVKIRMATFEDS
GKCKGFAFIDFKNEEGSTNALKDKSCRKIAGRPLRMEYGEDRSKRQVRKKVENVSRNN
SSSFDISNNKGYDRAGQDNGSKPEYKRSNANRRPPVDSNNRTKSSVALATAQRGSAAI
VPSQGKKVKFD"
gene complement(308957..310057)
/gene="MDG1"
/locus_tag="YNL173C"
/db_xref="GeneID:855548"
mRNA complement(308957..310057)
/gene="MDG1"
/locus_tag="YNL173C"
/product="Mdg1p"
/transcript_id="NM_001183011.1"
/db_xref="GI:296147597"
/db_xref="GeneID:855548"
CDS complement(308957..310057)
/gene="MDG1"
/locus_tag="YNL173C"
/note="Plasma membrane protein involved in G-protein
mediated pheromone signaling pathway; overproduction
suppresses bem1 mutations"
/codon_start=1
/product="Mdg1p"
/protein_id="NP_014226.1"
/db_xref="GI:6324156"
/db_xref="SGD:S000005117"
/db_xref="GeneID:855548"
/translation="MQSSLPQFTFKWPKGPEAIILTGTFDDWKGTLPMVKDPSGAFEI
TLPVTFDSPSSKFYFKFIVDGQWLPSKDYKVNIDEGVENNFITEEDVIKQRENGSSTL
VPESAGLAVSKNAPLIEPEAEKRAKKLRKFKIKRVIKTNKQTGERSIFSQEVVELPDS
EDETQQVNKTGKNADGLSGTTTIIENNVGVNEEKAIKPYEENHPKVNLVKSEGYVTDG
LGKTQSSESRLYELSAEDLEKEEEEEDEDKGGGKDTSTSADAEASEDQNKEPLSKSAK
FEKPEEKVPVSSITSHAKETSVKPTGKVATETQTYETKQGAPTAAAKKIEAKKATRPS
KPKGTKETPNKGVQKNPAKNGGFFKKLAQLLK"
gene 310636..315882
/gene="APC1"
/locus_tag="YNL172W"
/db_xref="GeneID:855549"
mRNA 310636..315882
/gene="APC1"
/locus_tag="YNL172W"
/product="anaphase promoting complex subunit 1"
/transcript_id="NM_001183010.4"
/db_xref="GI:398364518"
/db_xref="GeneID:855549"
CDS 310636..315882
/gene="APC1"
/locus_tag="YNL172W"
/note="Largest subunit of the Anaphase-Promoting
Complex/Cyclosome; APC/C is a ubiquitin-protein ligase
required for degradation of anaphase inhibitors, including
mitotic cyclins, during the metaphase/anaphase transition;
component of the platform domain of the APC/C, based on
structural analysis; localizes to nuclear foci that become
diffuse upon DNA replication stress"
/codon_start=1
/product="anaphase promoting complex subunit 1"
/protein_id="NP_014227.4"
/db_xref="GI:398364519"
/db_xref="SGD:S000005116"
/db_xref="GeneID:855549"
/translation="MTSKPSTRNDYLPRETHNGEYTGDSPEWQLQINITNKIGGINGD
IWLSRDGRSVKWCIEDQCLRQFTYNQKIIKAGYIDFEKTPDCFVVVLSDIAHVYMLKN
GGSTTVCFPFQIGNAFWYANGVILERETSASFMDGGYDLKPIEFDLKHKYITLTDPMA
PFGLISITNTFKGGINSASGNKTDILQDFQLVLFPSDKDKCIAVFLDRNSKVLRFYYS
RILSSDQSRKGELTISSTKKTGLDAAGNSQKSGGISKDLRKFSHLTRRSTSINSNSHD
FNAAERVLSGNVGNASGRTDIFALPSSCSRRSLSATLDRMGNNIAPTNRAAPSGFFDS
SSANTATHSNITPVSQPMQQQQQEYLNQTATSSKDIVLTEISSLKLPDDIIFTSRRLS
SILSKLKFLSLRFERREGLLIFHEPTHFCKIWLIDLLPDVLDSIPFKIYGNSPQNMIR
LENLKLKEPSRIQAMYIHELLESCLILVSEGQNKEEYKACLYDPFVKITSPSKNISEE
LTKQNSLPSLQKLFPYPETSFTKLCFEAVKYITSPAFNISFIFLWQSAYSILLSRAND
DVVGGLKMEHDAFSLVLSLLILPIPSSSAQEYQEYKEIYERDLFQHLKQDSEITSSVL
PRIVIGLHLIREEYSLNVLCRNEHALLGQFLRFATAAMGWPDLWQSYYVPKMDSESKT
FLHPREQNSTFFHPLDEPPSITKSLYSITENSSIPLCPFISFSRLVATDTQVELRITP
RSFKILGLYELVHSPNFLPDYVLGILSSFKVDKDELQTYPLGILVPLQNILKILEDKL
SEVRDNLELLDRADLQRCSAIINSIRSDSKEVLKRGQRDSYMLCKVPLAKNRSSLSKK
PSDIYSILSEIVKSASQVPLDGSAMRMSNIQDDEDIDEGRSLKLNAGLIFSEDKRFTH
VVSLLAYYRPTKTQFFTTKTEYAQILAQKKYFAKIMALRTCTNGVGWGAVAYATEKPI
STQKWVIQPLNLISVFPDDTKITVKAPEDIAHDIVEWGQFHAGVSSGLRISKKATGIT
GSWIAFNKPKELDAYHGGFLLGLGLNGHLKNLEEWHIYNYLSPRNTHISIGLLLGMSS
SMKGSMDSKLIKVISVHLVAFLPSGSSDLNIDLKLQTAGIIGMGMLYLNSRHKRMSDS
IFAQLVSLLNVNDEMVADEEYRLAAGISLGLINLGAGQTKLRKWDSSLLGLGDDLPED
VYDSSDVEQNVMYEDLTTKLLEIVTSTYDVENDWIPENSQIGAVIAIMFLFLKSNNFG
ISNMLKVDLKEILKANINTRPELLMYREWASNMILWEFIGDDLSFIMKDVDIGVKFSE
LNTDLLPIYYTMAGRILAMGIRFASTGNLKIRNILLSLVDKFLPLYQYPGKQNLDFRL
TISVINVLTNVIVVSLSMVMCASGDLEVLRRVKYLHEVASGPYSDLFQEIPSSKSDVS
GVTQVTSNTNTPGNSDRERVDETAASLDDERSSNGSDISDPTAYLEDKKDIDDHYGKF
ISTNLALGFLFLGSGQYALNTSTLESIAFLSMSVLPTYTTPHPLQELKHFWSMAVEPR
CLVIKDISTGDAVNNVPIELVVEEDVEKEEVIREISTPCLLPDFSKIKSIRVKMHGYF
PLEVNFTKDYSASDFFSGGTIIYIQRKSESVFENKASFRNVEDIHVALKRKAAESKNY
SRLNLKNEQGNTTSSQLVESLGIQDLTMVELDTLLSAGNNTALTDSESYNLGLLCSDK
NSGDILDCQLELWYKSFGPHDE"
gene complement(316169..317671)
/gene="PSD1"
/locus_tag="YNL169C"
/db_xref="GeneID:855552"
mRNA complement(316169..317671)
/gene="PSD1"
/locus_tag="YNL169C"
/product="phosphatidylserine decarboxylase 1"
/transcript_id="NM_001183007.1"
/db_xref="GI:296147599"
/db_xref="GeneID:855552"
CDS complement(316169..317671)
/gene="PSD1"
/locus_tag="YNL169C"
/EC_number="4.1.1.65"
/note="Phosphatidylserine decarboxylase of the
mitochondrial inner membrane, converts phosphatidylserine
to phosphatidylethanolamine"
/codon_start=1
/product="phosphatidylserine decarboxylase 1"
/protein_id="NP_014230.1"
/db_xref="GI:6324160"
/db_xref="SGD:S000005113"
/db_xref="GeneID:855552"
/translation="MSIMPVKNALAQGRTLLMGRMPAVKFSTRMQLRNRTAVLWNRKF
STRLFVQQRRSSGEIVDRAKAAAANSGRKQVSMKWVVLTSFTIVLGTILLVSRNDSTE
EDATEGKKGRRTRKIKIFNNNWLFFCYSTLPLNAMSRLWGQVNSLTLPIWVRPWGYRL
YSFLFGVNLDEMEDPDLTHYANLSEFFYRNIKPGTRPVAQGEDVIASPSDGKILQVGI
INSETGEIEQVKGMTYSIKEFLGTHSHPLMSKSASSLDLTSDEEKHREFARVNRIQLA
GSEDTEQPLLNFKNEGDQSVREFKPSVSKNIHLLSQLSLNYFSNGFSCSEPHDTELFF
AVIYLAPGDYHHFHSPVDWVCKVRRHFPGDLFSVAPYFQRNFPNLFVLNERVALLGSW
KYGFFSMTPVGATNVGSIKLNFDQEFVTNSKSDKHLEPHTCYQAVYENASKILGGMPL
VKGEEMGGFELGSTVVLCFEAPTEFKFDVRVGDKVKMGQKLGIIGKNDLK"
gene complement(318030..318809)
/gene="FMP41"
/locus_tag="YNL168C"
/db_xref="GeneID:855553"
mRNA complement(318030..318809)
/gene="FMP41"
/locus_tag="YNL168C"
/product="Fmp41p"
/transcript_id="NM_001183006.1"
/db_xref="GI:296147600"
/db_xref="GeneID:855553"
CDS complement(318030..318809)
/gene="FMP41"
/locus_tag="YNL168C"
/EC_number="3.-.-.-"
/note="hypothetical protein; GFP-fusion protein is induced
in response to the DNA-damaging agent MMS; the authentic,
non-tagged protein is detected in highly purified
mitochondria in high-throughput studies"
/codon_start=1
/product="Fmp41p"
/protein_id="NP_014231.1"
/db_xref="GI:6324161"
/db_xref="SGD:S000005112"
/db_xref="GeneID:855553"
/translation="MSYNYLKAARKIICIGRNYAAHIKELNNSTPKQPFFFLKPTSSI
VTPLSSSLVKTTRPANSTFNGLNEDGTNPGPIFIPRGVKVHHEIELALIVSKHLSNVT
KMKPEEVYDSISGVALALDLTARNVQDEAKKKGLPWTISKGFDTFMPISAIVSREKFS
SYKSNLQDIFRVKCSVNGQLRQDGGTNLMLHPLHKILQHISTMISLEPGDIILTGTPA
GVGELKPGDRVHCELLQNNDNIVDMNFECENRPGPYEFRET"
gene complement(319416..321359)
/gene="SKO1"
/locus_tag="YNL167C"
/gene_synonym="ACR1"
/db_xref="GeneID:855554"
mRNA complement(319416..321359)
/gene="SKO1"
/locus_tag="YNL167C"
/gene_synonym="ACR1"
/product="Sko1p"
/transcript_id="NM_001183005.1"
/db_xref="GI:296147601"
/db_xref="GeneID:855554"
CDS complement(319416..321359)
/gene="SKO1"
/locus_tag="YNL167C"
/gene_synonym="ACR1"
/note="Basic leucine zipper transcription factor of the
ATF/CREB family; forms a complex with Tup1p and Cyc8p to
both activate and repress transcription; cytosolic and
nuclear protein involved in osmotic and oxidative stress
responses"
/codon_start=1
/product="Sko1p"
/protein_id="NP_014232.1"
/db_xref="GI:6324162"
/db_xref="SGD:S000005111"
/db_xref="GeneID:855554"
/translation="MSSEERSRQPSTVSTFDLEPNPFEQSFASSKKALSLPGTISHPS
LPKELSRNNSTSTITQHSQRSTHSLNSIPEENGNSTVTDNSNHNDVKKDSPSFLPGQQ
RPTIISPPILTPGGSKRLPPLLLSPSILYQANSTTNPSQNSHSVSVSNSNPSAIGVSS
TSGSLYPNSSSPSGTSLIRQPRNSNVTTSNSGNGFPTNDSQMPGFLLNLSKSGLTPNE
SNIRTGLTPGILTQSYNYPVLPSINKNTITGSKNVNKSVTVNGSIENHPHVNIMHPTV
NGTPLTPGLSSLLNLPSTGVLANPVFKSTPTTNTTDGTVNNSISNSNFSPNTSTKAAV
KMDNPAEFNAIEHSAHNHKENENLTTQIENNDQFNNKTRKRKRRMSSTSSTSKASRKN
SISRKNSAVTTAPAQKDDVENNKISNNVTLDENEEQERKRKEFLERNRVAASKFRKRK
KEYIKKIENDLQFYESEYDDLTQVIGKLCGIIPSSSSNSQFNVNVSTPSSSSPPSTSL
IALLESSISRSDYSSAMSVLSNMKQLICETNFYRRGGKNPRDDMDGQEDSFNKDTNVV
KSENAGYPSVNSRPIILDKKYSLNSGANISKSNTTTNNVGNSAQNIINSCYSVTNPLV
INANSDTHDTNKHDVLSTLPHNN"
rep_origin 321921..322213
/note="ARS1415;
Autonomously Replicating Sequence"
/db_xref="SGD:S000118385"
gene complement(322219..323565)
/gene="BNI5"
/locus_tag="YNL166C"
/db_xref="GeneID:855555"
mRNA complement(322219..323565)
/gene="BNI5"
/locus_tag="YNL166C"
/product="Bni5p"
/transcript_id="NM_001183004.1"
/db_xref="GI:296147602"
/db_xref="GeneID:855555"
CDS complement(322219..323565)
/gene="BNI5"
/locus_tag="YNL166C"
/note="Protein involved in organization of septins at the
mother-bud neck, may interact directly with the Cdc11p
septin, localizes to bud neck in a septin-dependent
manner"
/codon_start=1
/product="Bni5p"
/protein_id="NP_014233.1"
/db_xref="GI:6324163"
/db_xref="SGD:S000005110"
/db_xref="GeneID:855555"
/translation="MGLDQDKIKKRLSQIEIDINQMNQMIDENLQLVEPAEDEAVEDN
VKDTGVVDAVKVAETALFSGNDGADSNPGDSAQVEEHKTAQVHIPTENEANKSTDDPS
QLSVTQPFIAKEQITHTAIAIGDSYNSFVANSAGNEKAKDSCTENKEDGTVNIDQNRG
EADVEIIENNDDEWEDEKSDVEEGRVDKGTEENSEIESFKSPMPQNNTLGGENKLDAE
LVLDKFSSANKDLDIQPQTIVVGGDNEYNHESSRLADQTPHDDNSENCPNRSGGSTPL
DSQTKIFIPKKNSKEDGTNINHFNSDGDGQKKMANFETRRPTNPFRVISVSSNSNSRN
GSRKSSLNKYDSPVSSPITSASELGSIAKLEKRHDYLSMKCIKLQKEIDYLNKMNAQG
SLSMEDGKRLHRAVVKLQEYLDKKTKEKYEVGVLLSRHLRKQIDRGENGQFWIGTK"
gene 323832..325052
/locus_tag="YNL165W"
/db_xref="GeneID:855556"
mRNA 323832..325052
/locus_tag="YNL165W"
/product="hypothetical protein"
/transcript_id="NM_001183003.3"
/db_xref="GI:398364534"
/db_xref="GeneID:855556"
CDS 323832..325052
/locus_tag="YNL165W"
/note="hypothetical protein; YNL165W is not an essential
gene"
/codon_start=1
/product="hypothetical protein"
/protein_id="NP_014234.3"
/db_xref="GI:398364535"
/db_xref="SGD:S000005109"
/db_xref="GeneID:855556"
/translation="MDRVRSLIGNRRGRRHNRQHPPYPHSGSPSTVNLLGANGYGDDQ
STIFARENESLETSANEGDDSADAATLNTAVSEGSTIGDLQRQGYVNRAPRFTSERAM
PFVSVLLQRGFFAFPSEESLQLFLHNKRKLDNIDPKRGLGLPLFHAISLNLVKSLFSD
QNTPVMRIYKYVMIDSQCDKPPLNSEVVSRINENVSIYKYEFCTILKKMESHNFSSRV
EHDFIFHRKDEPDVHIPMINYNQRKNADTAIHGLNLRWYGTTSLASPFGSNSINLLVL
DDTMASYMNQQTIEEFDSYSRSRPTRPLGYLPVWARYTDDKVSVIPKKRTLRVATLYL
QETDSFDDGSSLTSTNYTEMGSNIIENVPWDSQILTCMCMLLHEYESRKEKRHTAWGS
STTYMLNGPAGLLM"
rep_origin 325054..325267
/note="ARS1416;
Putative replication origin, identified in multiple array
studies, not yet confirmed by plasmid-based assay"
/db_xref="SGD:S000130142"
gene complement(325265..326320)
/gene="IBD2"
/locus_tag="YNL164C"
/db_xref="GeneID:855557"
mRNA complement(325265..326320)
/gene="IBD2"
/locus_tag="YNL164C"
/product="Ibd2p"
/transcript_id="NM_001183002.1"
/db_xref="GI:296147604"
/db_xref="GeneID:855557"
CDS complement(325265..326320)
/gene="IBD2"
/locus_tag="YNL164C"
/note="Component of the BUB2-dependent spindle checkpoint
pathway, interacts with Bfa1p and functions upstream of
Bub2p and Bfa1p"
/codon_start=1
/product="Ibd2p"
/protein_id="NP_014235.1"
/db_xref="GI:6324165"
/db_xref="SGD:S000005108"
/db_xref="GeneID:855557"
/translation="MTPTNQSSGTTNASVEVLSEDGPMPINVMMQEGVKALTKILSNQ
LQDRQAFQNAPHAMQFVIRNGGKALSNARLEELKDALPKMDSLSLEDELAKIDGQSAY
HIDSAEEKETFESKIGQIASRNSADFIIEEDLQNILDDDLKDSELNLDGEEAEIIFDY
ESQELDTPDGIGEKISQMIESVLPGGFGSEEQGGLRTVTNVEDLDVAEEVTDIDHDTV
DAARLHGDGQHSISSRKHSRSKNSKKNGHVRRHDFYDESRDHKSCCPHHHYENLSKLR
NYYYHDFEYISRTENRVPDFSVLVNESSPMCLFCEYYMVFGEPPRNMIKWYNRTFGYN
RMPNPPRDEQDSRKRNR"
gene complement(326741..330073)
/gene="RIA1"
/locus_tag="YNL163C"
/gene_synonym="EFL1"
/db_xref="GeneID:855558"
mRNA complement(326741..330073)
/gene="RIA1"
/locus_tag="YNL163C"
/gene_synonym="EFL1"
/product="Ria1p"
/transcript_id="NM_001183001.1"
/db_xref="GI:296147605"
/db_xref="GeneID:855558"
CDS complement(326741..330073)
/gene="RIA1"
/locus_tag="YNL163C"
/gene_synonym="EFL1"
/note="Cytoplasmic GTPase/eEF2-like factor involved in
ribosomal biogenesis; with Sdo1p, promotes release of
Tif6p from 60S ribosomal subunits in the cytoplasm so that
they can assemble with 40S subunits to generate mature
ribosomes; required for quality control check of newly
made large ribosomal subunits before they are released
into the pool of translating ribosomes"
/codon_start=1
/product="Ria1p"
/protein_id="NP_014236.1"
/db_xref="GI:6324166"
/db_xref="SGD:S000005107"
/db_xref="GeneID:855558"
/translation="MPRVESETYKRLQNDPSCIRNICIVAHVDHGKTSLSDSLLASNG
IISQRLAGKIRFLDARPDEQLRGITMESSAISLYFRVLRKQEGSDEPLVSEHLVNLID
SPGHIDFSSEVSAASRLCDGAVVLVDVVEGVCSQTVTVLRQCWTEKLKPILVLNKIDR
LITELQLTPQEAYIHLSKVIEQVNSVIGSFFANERQLDDLFWREQLEKNENAEYIEKD
DSGIYFNPTDNNVIFASAIDGWGFNIGQLAKFYEQKLGAKRENLQKVLWGDFYMDPKT
KKIINNKGLKGRSLKPLFTSLILENIWKIYQNIITSRDSEMVEKIAKTLNIKLLARDL
RSKDDKQLLRTIMGQWLPVSTAVLLTVIEKLPSPLESQTDRLNTILVSESDTAAMDPR
LLKAMKTCDKEGPVSAYVSKMLSIPREELPVESKRIASSDELMERSRKAREEALNAAK
HAGMVENMAMMDLNDNSKNTSDLYKRAKDTVMTPEVGEQTKPKPSRNNDVFCVVSEPS
SALDLEFEYEGEDDSDSQDNFGLDFVPTDIDPNDPLSSMFEYEEEDPLLESIKQISED
VNDEVDDIFDEKEECLVAFARIYSGTLRVGQEISVLGPKYDPKCPEEHIETAIITHLY
LFMGKELVPLDVCPSGNIVGIRGLAGKVLKSGTLIEKGVQGVNLAGVNFHFTPIVRVA
VEPANPVEMSKLVRGLKLLDQADPCVHTYVENTGEHILCTAGELHLERCLKDLTERFA
GIEITHSEPAIPYRETFLSASDMNPPQNSQLGRGVHELLLSQYKITFRTFPLSGKVTD
FLSQHQNSIKNILKTSTSSMDPVIESTGSSFLDKKSLLVAFEEVINQEEKSRELLSGF
KVKLAGFGPSRVGCNILLSQDNLLGSLFEGTPAAFEYSDSIKNGFQLAVSEGPLANEP
VQGMCVLVESVHKMSQDEIESIEDPRYQQHIVDLSGRLITSTRDAIHEAFLDWSPRIM
WAIYSCDIQTSVDVLGKVYAVILQRHGKIISEEMKEGTPFFQIEAHVPVVEAFGLSED
IRKRTSGAAQPQLVFSGFECIDLDPFWVPTTEEELEELGDTADRENIARKHMNAIRRR
KGLFIEEKVVENAEKQRTLKKN"
gene 330329..330547
/locus_tag="YNL162W-A"
/db_xref="GeneID:855559"
mRNA 330329..330547
/locus_tag="YNL162W-A"
/product="hypothetical protein"
/transcript_id="NM_001184490.1"
/db_xref="GI:296147606"
/db_xref="GeneID:855559"
CDS 330329..330547
/locus_tag="YNL162W-A"
/note="hypothetical protein; identified by homology"
/codon_start=1
/product="hypothetical protein"
/protein_id="NP_076906.1"
/db_xref="GI:13129184"
/db_xref="SGD:S000007624"
/db_xref="GeneID:855559"
/translation="MSDKPDSQVFCPNCNERLQKCLVQQNYAIIICPSLVCGYPFNQR
EVLENLTYVDDNDVLKVAKKRLSSRSKP"
gene 331322..332154
/gene="RPL42A"
/locus_tag="YNL162W"
/db_xref="GeneID:855560"
mRNA join(331322..331325,331838..332154)
/gene="RPL42A"
/locus_tag="YNL162W"
/product="ribosomal 60S subunit protein L42A"
/transcript_id="NM_001183000.1"
/db_xref="GI:296147607"
/db_xref="GeneID:855560"
CDS join(331322..331325,331838..332154)
/gene="RPL42A"
/locus_tag="YNL162W"
/note="Ribosomal 60S subunit protein L42A; homologous to
mammalian ribosomal protein L36A, no bacterial homolog;
RPL42A has a paralog, RPL42B, that arose from the whole
genome duplication"
/codon_start=1
/product="ribosomal 60S subunit protein L42A"
/protein_id="NP_014237.2"
/db_xref="GI:6681849"
/db_xref="SGD:S000005106"
/db_xref="GeneID:855560"
/translation="MVNVPKTRKTYCKGKTCRKHTQHKVTQYKAGKASLFAQGKRRYD
RKQSGFGGQTKPVFHKKAKTTKKVVLRLECVKCKTRAQLTLKRCKHFELGGEKKQKGQ
ALQF"
gene 332597..334867
/gene="CBK1"
/locus_tag="YNL161W"
/db_xref="GeneID:855561"
mRNA 332597..334867
/gene="CBK1"
/locus_tag="YNL161W"
/product="Cbk1p"
/transcript_id="NM_001182999.3"
/db_xref="GI:398364550"
/db_xref="GeneID:855561"
CDS 332597..334867
/gene="CBK1"
/locus_tag="YNL161W"
/EC_number="2.7.11.1"
/note="Serine/threonine protein kinase of the the RAM
signaling network; Ndr/LATS family member; binds
regulatory subunit Mob2p; involved in regulation of
cellular morphogenesis, polarized growth, and septum
destruction; phosphorylation by Cbk1p regulates
localization and activity of Ace2p transcription factor
and Ssd1p translational repressor; Cbk1p activity is
regulated by both phosphorylation and specific
localization; relocalizes to cytoplasm upon DNA
replication stress"
/codon_start=1
/product="Cbk1p"
/protein_id="NP_014238.3"
/db_xref="GI:398364551"
/db_xref="SGD:S000005105"
/db_xref="GeneID:855561"
/translation="MYNSSTNHHEGAPTSGHGYYMSQQQDQQHQQQQQYANEMNPYQQ
IPRPPAAGFSSNYMKEQGSHQSLQEHLQRETGNLGSGFTDVPALNYPATPPPHNNYAA
SNQMINTPPPSMGGLYRHNNNSQSMVQNGNGSGNAQLPQLSPGQYSIESEYNQNLNGS
SSSSPFHQPQTLRSNGSYSSGLRSVKSFQRLQQEQENVQVQQQLSQAQQQNSRQQQQQ
LQYQQQQQQQQQQQHMQIQQQQQQQQQQQQSQSPVQSGFNNGTISNYMYFERRPDLLT
KGTQDKAAAVKLKIENFYQSSVKYAIERNERRVELETELTSHNWSEERKSRQLSSLGK
KESQFLRLRRTRLSLEDFHTVKVIGKGAFGEVRLVQKKDTGKIYAMKTLLKSEMYKKD
QLAHVKAERDVLAGSDSPWVVSLYYSFQDAQYLYLIMEFLPGGDLMTMLIRWQLFTED
VTRFYMAECILAIETIHKLGFIHRDIKPDNILIDIRGHIKLSDFGLSTGFHKTHDSNY
YKKLLQQDEATNGISKPGTYNANTTDTANKRQTMVVDSISLTMSNRQQIQTWRKSRRL
MAYSTVGTPDYIAPEIFLYQGYGQECDWWSLGAIMYECLIGWPPFCSETPQETYRKIM
NFEQTLQFPDDIHISYEAEDLIRRLLTHADQRLGRHGGADEIKSHPFFRGVDWNTIRQ
VEAPYIPKLSSITDTRFFPTDELENVPDSPAMAQAAKQREQMTKQGGSAPVKEDLPFI
GYTYSRFDYLTRKNAL"
gene 336545..337609
/gene="YGP1"
/locus_tag="YNL160W"
/db_xref="GeneID:855562"
mRNA 336545..337609
/gene="YGP1"
/locus_tag="YNL160W"
/product="Ygp1p"
/transcript_id="NM_001182998.1"
/db_xref="GI:296147609"
/db_xref="GeneID:855562"
CDS 336545..337609
/gene="YGP1"
/locus_tag="YNL160W"
/note="Cell wall-related secretory glycoprotein; induced
by nutrient deprivation-associated growth arrest and upon
entry into stationary phase; may be involved in adaptation
prior to stationary phase entry; has similarity to
Sps100p"
/codon_start=1
/product="Ygp1p"
/protein_id="NP_014239.1"
/db_xref="GI:6324169"
/db_xref="SGD:S000005104"
/db_xref="GeneID:855562"
/translation="MKFQVVLSALLACSSAVVASPIENLFKYRAVKASHSKNINSTLP
AWNGSNSSNVTYANGTNSTTNTTTAESSQLQIIVTGGQVPITNSSLTHTNYTRLFNSS
SALNITELYNVARVVNETIQDKSSAGAVVVANAKSLEAVSFFFSIIFDTEKPIVVTED
SAYAIPVANNKNATKRGVLSVTSDKLVYSGVFTPPTACSYGAGLPVAIVDDQDEVKWF
FDASKPTLISSDSIIRKEYSNFTTPYGLLENGVPIVPIVYDGGYSSSLIDSLSSAVQG
LVVVSSGSTNSTSSTIESTEIPVVYAQANTPLNFIDNKDVPKNAVGAGYLSPIKAQIL
LSIAAVNGVTSKSALESIFP"
gene complement(338478..339347)
/gene="ASI2"
/locus_tag="YNL159C"
/db_xref="GeneID:855563"
mRNA complement(338478..339347)
/gene="ASI2"
/locus_tag="YNL159C"
/product="Asi2p"
/transcript_id="NM_001182997.1"
/db_xref="GI:296147610"
/db_xref="GeneID:855563"
CDS complement(338478..339347)
/gene="ASI2"
/locus_tag="YNL159C"
/note="Integral inner nuclear membrane protein that acts
with Asi1p and Asi3p to ensure the fidelity of SPS-sensor
signalling by maintaining the dormant repressed state of
gene expression in the absence of inducing signals"
/codon_start=1
/product="Asi2p"
/protein_id="NP_014240.1"
/db_xref="GI:6324170"
/db_xref="SGD:S000005103"
/db_xref="GeneID:855563"
/translation="MARPQNHRRSNWTERDDNDDYLFQRFLEESETRHSREPSPVTEQ
SQQELQQDVQQAIDGIFNSLRRNMSSTSNINRAANMDATTNGNGGINADTIRATNANT
ADSPFTARQQSPLRTFLRNLFILDYFIGLILFPFSVYNILRSGFNSMTFSENDFIIEI
VGYWKFAKIFGSGGTTLIAYKDTGKLGLLGKFHNIIVFYSSPVIKHIMKSRDGNEPNL
NWIRLMFAKAFELFVKVSTILIYLAYGVSGTVYMVTAGFFFVLCLLFTVIRRYKGVHR
MLVSQRITGPGVF"
gene 339612..340208
/gene="PGA1"
/locus_tag="YNL158W"
/db_xref="GeneID:855564"
mRNA 339612..340208
/gene="PGA1"
/locus_tag="YNL158W"
/product="Pga1p"
/transcript_id="NM_001182996.1"
/db_xref="GI:296147611"
/db_xref="GeneID:855564"
CDS 339612..340208
/gene="PGA1"
/locus_tag="YNL158W"
/note="Essential component of GPI-mannosyltransferase II,
responsible for second mannose addition to GPI precursors
as a partner of Gpi18p; required for maturation of Gas1p
and Pho8p; has synthetic genetic interations with
secretory pathway genes"
/codon_start=1
/product="Pga1p"
/protein_id="NP_014241.1"
/db_xref="GI:6324171"
/db_xref="SGD:S000005102"
/db_xref="GeneID:855564"
/translation="MVRPQNVHWFIATIVFFIGFVHANTESILYKVPHNFPLKKPRDS
STYARDVNLISSISLSGEAMSQITIEANTTDLELHNTTYIELADLQRDETYQIKVCWS
AIHPISINNLQTITIPRFTEFQGTKSDYARILVTFQVLSDSYPSEHAMVPIQVSLITT
RLGIPVDIYPTLIVMVLLVAGLVVTRAPHVLNDLLLKF"
gene 340352..340858
/gene="IGO1"
/locus_tag="YNL157W"
/db_xref="GeneID:855565"
mRNA 340352..340858
/gene="IGO1"
/locus_tag="YNL157W"
/product="Igo1p"
/transcript_id="NM_001182995.1"
/db_xref="GI:296147612"
/db_xref="GeneID:855565"
CDS 340352..340858
/gene="IGO1"
/locus_tag="YNL157W"
/note="Protein required for initiation of G0 program;
prevents degradation of nutrient-regulated mRNAs via the
5'-3' mRNA decay pathway; phosphorylated by Rim15p; GFP
protein localizes to the cytoplasm and nucleus; similar to
Igo2p"
/codon_start=1
/product="Igo1p"
/protein_id="NP_014242.1"
/db_xref="GI:6324172"
/db_xref="SGD:S000005101"
/db_xref="GeneID:855565"
/translation="MSNENLSPNSSNPDLTKLNNGESGTIDTSKFSPNEMKLYKMYGK
LPSKKDIFKHTMQKRKYFDSGDYALQKAGIQNNDPINYGKNNLPLTNPSKLREDIIKR
RISTCPSTASTAGVVDNATLIQKEGSISSGPPSSNNGTIGGGSTSSTPVGNHSSSSSS
LYTESPIR"
gene complement(341069..341968)
/gene="NSG2"
/locus_tag="YNL156C"
/db_xref="GeneID:855566"
mRNA complement(341069..341968)
/gene="NSG2"
/locus_tag="YNL156C"
/product="Nsg2p"
/transcript_id="NM_001182994.3"
/db_xref="GI:398364568"
/db_xref="GeneID:855566"
CDS complement(341069..341968)
/gene="NSG2"
/locus_tag="YNL156C"
/note="Protein involved in regulation of sterol
biosynthesis; specifically stabilizes Hmg2p, one of two
HMG-CoA isoenzymes that catalyze the rate-limiting step in
sterol biosynthesis; homolog of mammalian INSIG proteins"
/codon_start=1
/product="Nsg2p"
/protein_id="NP_014243.3"
/db_xref="GI:398364569"
/db_xref="SGD:S000005100"
/db_xref="GeneID:855566"
/translation="MANRGEPDPKKSTESICSLTKPQLYSLYDDDVVRSEDNEIYEEL
KRSVSIDSTKYSRDQTIDSTFYLAHKVGGSLPRNTVSSNNLERILSASSIHENFPSRT
RQTRQNILHYLQAVLILSLSGFAYHELSRNLHDNHLLHPDFASRPLLLGVKLCNWLSN
GVLPNWLGYGVEGLLFGSVVPILDNIFQTEVVKSSVHHDSLTSVIRSINAMLGVTFGI
RKIQWNSSLQAAGAWGLLNIILWLFFDGSISMLMSCICIGVGCCISCYKDIIDGSQFL
YFMDFYFLGSLMFGKLGRYLYSH"
gene 342516..343340
/locus_tag="YNL155W"
/db_xref="GeneID:855567"
mRNA 342516..343340
/locus_tag="YNL155W"
/product="hypothetical protein"
/transcript_id="NM_001182993.1"
/db_xref="GI:296147614"
/db_xref="GeneID:855567"
CDS 342516..343340
/locus_tag="YNL155W"
/note="hypothetical protein; contains a DHHC domain and an
AN1-type zinc finger; predicted to have thiol-disulfide
oxidoreductase active site; transcriptionally regulated by
Rpn4p along with proteasome subunit genes; putative
ortholog of human AIRAP, which stimulates proteasome
activity in response to arsenic; protein abundance
increases in response to DNA replication stress"
/codon_start=1
/product="hypothetical protein"
/protein_id="NP_014244.1"
/db_xref="GI:6324174"
/db_xref="SGD:S000005099"
/db_xref="GeneID:855567"
/translation="MSAAIEKETGMLDVGKHCAYCRQLDFLPFHCSFCNEDFCSNHRL
KEDHHCRWLLEHEEVHKTEKSPSKSRDGSSSNDEAYFKSLLPERASVRIQRVSETREP
LRGSNTAKVSSTLNSKTLDKIFKFFQRNEKRKSNNKSKKNFGSSSNKIIQLANLKKIA
KGDPKIPMQNRIYIWCYLVDGDETDIAKEDTRMPLYINKMWPVGRAMDYLSIQLNVKS
STLTNSSSNDKFQLCKLKEGKQVSFYNIGASLRVTNEIKDLDTLYLVHNNADEKSN"
gene complement(343636..345276)
/gene="YCK2"
/locus_tag="YNL154C"
/db_xref="GeneID:855568"
mRNA complement(343636..345276)
/gene="YCK2"
/locus_tag="YNL154C"
/product="Yck2p"
/transcript_id="NM_001182992.1"
/db_xref="GI:296147615"
/db_xref="GeneID:855568"
CDS complement(343636..345276)
/gene="YCK2"
/locus_tag="YNL154C"
/EC_number="2.7.11.1"
/note="Palmitoylated plasma membrane-bound casein kinase I
isoform; shares redundant functions with Yck1p in
morphogenesis, proper septin assembly, endocytic
trafficking; provides an essential function overlapping
with that of Yck1p"
/codon_start=1
/product="Yck2p"
/protein_id="NP_014245.1"
/db_xref="GI:6324175"
/db_xref="SGD:S000005098"
/db_xref="GeneID:855568"
/translation="MSQVQSPLTATNSGLAVNNNTMNSQMPNRSNVRLVNGTLPPSLH
VSSNLNHNTGNSSASYSGSQSRDDSTIVGLHYKIGKKIGEGSFGVLFEGTNMINGLPV
AIKFEPRKTEAPQLKDEYRTYKILAGTPGIPQEYYFGQEGLHNILVIDLLGPSLEDLF
DWCGRRFSVKTVVQVAVQMITLIEDLHAHDLIYRDIKPDNFLIGRPGQPDANKVHLID
FGMAKQYRDPKTKQHIPYREKKSLSGTARYMSINTHLGREQSRRDDMEAMGHVFFYFL
RGQLPWQGLKAPNNKQKYEKIGEKKRLTNVYDLAQGLPIQFGRYLEIVRNLSFEETPD
YEGYRMLLLSVLDDLGETADGQYDWMKLNGGRGWDLSINKKPNLHGYGHPNPPNEKSK
RHRSKNHQYSSPDHHHHYNQQQQQQQAQAQAQAQAQAKVQQQQLQQAQAQQQANRYQL
QPDDSHYDEEREASKLDPTSYEAYQQQTQQKYAQQQQKQMQQKSKQFANTGANGQTNK
YPYNAQPTANDEQNAKNAAQDRNSNKSSKGFFSKLGCC"
gene complement(345669..346058)
/gene="GIM3"
/locus_tag="YNL153C"
/gene_synonym="PFD4"
/db_xref="GeneID:855569"
mRNA complement(345669..346058)
/gene="GIM3"
/locus_tag="YNL153C"
/gene_synonym="PFD4"
/product="Gim3p"
/transcript_id="NM_001182991.1"
/db_xref="GI:296147616"
/db_xref="GeneID:855569"
CDS complement(345669..346058)
/gene="GIM3"
/locus_tag="YNL153C"
/gene_synonym="PFD4"
/note="Subunit of the heterohexameric cochaperone
prefoldin complex which binds specifically to cytosolic
chaperonin and transfers target proteins to it"
/codon_start=1
/product="Gim3p"
/protein_id="NP_014246.1"
/db_xref="GI:6324176"
/db_xref="SGD:S000005097"
/db_xref="GeneID:855569"
/translation="MELLPQGQRNNTQVTFEDQQKINEFSKLIMRKDAIAQELSLQRE
EKEYLDDVSLEIELIDEDEPVQYKVGDLFIFMKQSKVTAQLEKDAERLDNKIETLEDK
QRDIDSRLDALKAILYAKFGDNINLER"
gene 346313..347542
/gene="INN1"
/locus_tag="YNL152W"
/db_xref="GeneID:855570"
mRNA 346313..347542
/gene="INN1"
/locus_tag="YNL152W"
/product="Inn1p"
/transcript_id="NM_001182990.1"
/db_xref="GI:296147617"
/db_xref="GeneID:855570"
CDS 346313..347542
/gene="INN1"
/locus_tag="YNL152W"
/note="Essential protein that associates with the
contractile actomyosin ring, required for ingression of
the plasma membrane into the bud neck during cytokinesis;
C2 domain, a membrane targeting module, is required for
function"
/codon_start=1
/product="Inn1p"
/protein_id="NP_014247.1"
/db_xref="GI:6324177"
/db_xref="SGD:S000005096"
/db_xref="GeneID:855570"
/translation="MSEEVWNGNQGILSVYVSKARDLPNLNKLDKQNVMLRLRIAHMT
RASNTLHRAGQNPVFHYLEKFDITPEIKPLMYVEVYCDRRKKSPLPIGRCEIDLLNAI
RADPKEGYCTWYELKRSGDEFAGTIFIELTFTPKVPRLNRDDLNKEMDRLDSSMAMRP
IPPLPTESEYDYVHGSTMRQITPQCVSTSHEDKDEGQPYRNGNVFSMSSKSDTAVLAN
SNDPIILPPTFSASMGTTSTLETNDTAISNTSNTKFHFANLRKLKEKINIFKNPDSST
NNCQNESNKVDIEALQKAIGVTSLSYDEDDDDDDENDAFYSSSHRVSHNYNQPPLPPI
PTRDDMSNYSSSRNTPLVRRDRPSRLDSSSPNSHPHPSGLNSPKLPPLPTTSNSNFNS
RKNSMSPTRKRPPPRLS"
gene complement(347766..348521)
/gene="RPC31"
/locus_tag="YNL151C"
/gene_synonym="ACP2; RPC8"
/db_xref="GeneID:855571"
mRNA complement(347766..348521)
/gene="RPC31"
/locus_tag="YNL151C"
/gene_synonym="ACP2; RPC8"
/product="Rpc31p"
/transcript_id="NM_001182989.3"
/db_xref="GI:398364596"
/db_xref="GeneID:855571"
CDS complement(347766..348521)
/gene="RPC31"
/locus_tag="YNL151C"
/gene_synonym="ACP2; RPC8"
/note="RNA polymerase III subunit C31"
/codon_start=1
/product="Rpc31p"
/protein_id="NP_014248.3"
/db_xref="GI:398364597"
/db_xref="SGD:S000005095"
/db_xref="GeneID:855571"
/translation="MSSYRGGSRGGGSNYMSNLPFGLGYGDVGKNHITEFPSIPLPIN
GPITNKERSLAVKYINFGKTVKDGPFYTGSMSLIIDQQENSKSGKRKPNIILDEDDTN
DGIERYSDKYLKKRKIGISIDDHPYNLNLFPNELYNVMGINKKKLLAISKFNNADDVF
TGTGLQDENIGLSMLAKLKELAEDVDDASTGDGAAKGSKTGEGEDDDLADDDFEEDED
EEDDDDYNAEKYFNNGDDDDYGDEEDPNEEAAF"
gene complement(349367..349756)
/gene="PGA2"
/locus_tag="YNL149C"
/db_xref="GeneID:855573"
mRNA complement(349367..349756)
/gene="PGA2"
/locus_tag="YNL149C"
/product="Pga2p"
/transcript_id="NM_001182987.1"
/db_xref="GI:296147619"
/db_xref="GeneID:855573"
CDS complement(349367..349756)
/gene="PGA2"
/locus_tag="YNL149C"
/note="Essential protein required for maturation of Gas1p
and Pho8p; involved in protein trafficking; GFP-fusion
protein localizes to the ER and YFP-fusion protein to the
nuclear envelope-ER network; null mutants have a cell
separation defect"
/codon_start=1
/product="Pga2p"
/protein_id="NP_014250.1"
/db_xref="GI:6324180"
/db_xref="SGD:S000005093"
/db_xref="GeneID:855573"
/translation="MSEVAETWVDTWMAKLVNYDYKHFIRLVIIVGGYLLLRNIASRE
LAKKQLAAQVEKDKRDKEEKRSKDLIDKPDDAATAETTSFGWGKKTRRRVKRQQELFE
NALEEAKRRNQGLDPDSDADIEELLEE"
gene complement(349907..350671)
/gene="ALF1"
/locus_tag="YNL148C"
/db_xref="GeneID:855574"
mRNA complement(349907..350671)
/gene="ALF1"
/locus_tag="YNL148C"
/product="Alf1p"
/transcript_id="NM_001182986.1"
/db_xref="GI:296147620"
/db_xref="GeneID:855574"
CDS complement(349907..350671)
/gene="ALF1"
/locus_tag="YNL148C"
/note="Alpha-tubulin folding protein, similar to mammalian
cofactor B; Alf1p-GFP localizes to cytoplasmic
microtubules; required for the folding of alpha-tubulin
and may play an additional role in microtubule
maintenance"
/codon_start=1
/product="Alf1p"
/protein_id="NP_014251.1"
/db_xref="GI:6324181"
/db_xref="SGD:S000005092"
/db_xref="GeneID:855574"
/translation="MVRVVIESELVRTEKELPNSLKLRQFKDRLYHVTGVEPEDMEIV
VKRQYDNKEIYSTKKGGAYSNEDEDANFLKGEEELIVVVTDSNAQSISNQLATQAEGI
PSMEVISEEDYLRRDQSVLRWKMAHGYGRFNAAQQSQRAALAKQDEAYAREQLTAAIG
RHCRVTVDGSAPREAILRYVGPLPLDVMGTWCGVEFPEAAGKNDGRINGVTLFGPVAP
GHGSFVRPRAVEILSKDEESAEVEDVHDDVESDDEI"
gene 350940..351383
/gene="LSM7"
/locus_tag="YNL147W"
/db_xref="GeneID:855575"
mRNA join(350940..350957,351054..351383)
/gene="LSM7"
/locus_tag="YNL147W"
/product="Lsm7p"
/transcript_id="NM_001182985.1"
/db_xref="GI:296147621"
/db_xref="GeneID:855575"
CDS join(350940..350957,351054..351383)
/gene="LSM7"
/locus_tag="YNL147W"
/note="Lsm (Like Sm) protein; part of heteroheptameric
complexes (Lsm2p-7p and either Lsm1p or 8p): cytoplasmic
Lsm1p complex involved in mRNA decay; nuclear Lsm8p
complex part of U6 snRNP and possibly involved in
processing tRNA, snoRNA, and rRNA; protein abundance
increases and forms cytoplasmic foci in response to DNA
replication stress"
/codon_start=1
/product="Lsm7p"
/protein_id="NP_014252.2"
/db_xref="GI:158267618"
/db_xref="SGD:S000005091"
/db_xref="GeneID:855575"
/translation="MHQQHSKSENKPQQQRKKFEGPKREAILDLAKYKDSKIRVKLMG
GKLVIGVLKGYDQLMNLVLDDTVEYMSNPDDENNTELISKNARKLGLTVIRGTILVSL
SSAEGSDVLYMQK"
gene complement(351386..351580)
/locus_tag="YNL146C-A"
/db_xref="GeneID:1466510"
mRNA complement(351386..351580)
/locus_tag="YNL146C-A"
/product="hypothetical protein"
/transcript_id="NM_001184663.1"
/db_xref="GI:296147622"
/db_xref="GeneID:1466510"
CDS complement(351386..351580)
/locus_tag="YNL146C-A"
/codon_start=1
/product="hypothetical protein"
/protein_id="NP_878152.1"
/db_xref="GI:33438864"
/db_xref="SGD:S000028851"
/db_xref="GeneID:1466510"
/translation="MISVCFVFPHSLALDFKSRCKKNRTKLCSAYYVSQVLRICKEMP
YRDLILFSTVRKGVYMRLYY"
gene 351715..352017
/locus_tag="YNL146W"
/db_xref="GeneID:855576"
mRNA 351715..352017
/locus_tag="YNL146W"
/product="hypothetical protein"
/transcript_id="NM_001182984.3"
/db_xref="GI:398364628"
/db_xref="GeneID:855576"
CDS 351715..352017
/locus_tag="YNL146W"
/note="hypothetical protein; green fluorescent protein
(GFP)-fusion protein localizes to the endoplasmic
reticulum; YNL146W is not an essential gene"
/codon_start=1
/product="hypothetical protein"
/protein_id="NP_014253.3"
/db_xref="GI:398364629"
/db_xref="SGD:S000005090"
/db_xref="GeneID:855576"
/translation="MSNTKHTTSHHMELKRIIILTLLFILIMLIFRNSVSFKMTFQEL
LPRFYKKNSNSVSNNNRPSSIFSENLVDFDDVNMVDKTRLFIFLFFSFIITIPFMV"
gene 352414..352530
/gene="MFA2"
/locus_tag="YNL145W"
/db_xref="GeneID:855577"
mRNA 352414..352530
/gene="MFA2"
/locus_tag="YNL145W"
/product="Mfa2p"
/transcript_id="NM_001182983.1"
/db_xref="GI:296147624"
/db_xref="GeneID:855577"
CDS 352414..352530
/gene="MFA2"
/locus_tag="YNL145W"
/note="Mating pheromone a-factor, made by a cells;
interacts with alpha cells to induce cell cycle arrest and
other responses leading to mating; biogenesis involves
C-terminal modification, N-terminal proteolysis, and
export; also encoded by MFA1"
/codon_start=1
/product="Mfa2p"
/protein_id="NP_014254.1"
/db_xref="GI:6324184"
/db_xref="SGD:S000005089"
/db_xref="GeneID:855577"
/translation="MQPITTASTQATQKDKSSEKKDNYIIKGLFWDPACVIA"
gene complement(352820..355042)
/locus_tag="YNL144C"
/db_xref="GeneID:855578"
mRNA complement(352820..355042)
/locus_tag="YNL144C"
/product="hypothetical protein"
/transcript_id="NM_001182982.1"
/db_xref="GI:296147625"
/db_xref="GeneID:855578"
CDS complement(352820..355042)
/locus_tag="YNL144C"
/note="hypothetical protein; non-tagged protein is
detected in highly purified mitochondria in
high-throughput studies; contains a PH domain and binds
phosphatidylinositols and phosphatidylethanolamine in a
large-scale study"
/codon_start=1
/product="hypothetical protein"
/protein_id="NP_014255.1"
/db_xref="GI:6324185"
/db_xref="SGD:S000005088"
/db_xref="GeneID:855578"
/translation="MSSSIFEMTIDHDGMDSTGLKLSQTASSISMGDEFLCSSTTSNS
ILDSPLPKVTFNHIDSITDINTNIMNEIVEPQSGVDVDVADKNVLYCIDPYPVEPPCY
DFANPSKVIRYPIYEHCRPCLTSVKPPSYTPSVEHYTVVSMKMEKLSPFENASSRLWN
NFILQINSTQINFYSIDDSLTRHIKNYRGGDMFDHSHHSKTASDRHHSARSLLNAFTT
KSTYQFDKYDKERICGEIARDEHKFLSDERLFKSYSLQCAKVGLPIDYSSRDFVLRMR
CEGQQFLVQFSHVDELIYWAMYLNMGISLSLDLELREMPTYRSVPRRRHPRARRFKQH
NKNKNKNKSRQNSDRNDSRSHSLLLRRSHTSSVVTKVATGNERPTNKSRSRSLSLLPP
SVSDASHDSNGPNDSGSLAGESSQTDFCGLFTSKLRNFFKTDSSSRKNSNMDIGQKMR
SKELNSVQEEIDDNGSTTNTNTSVLSSTFSPTAHSVLTAQTSIHENFRSRSNSNPIDP
LRCDRSVLKINNFEPVYEGTGRSTISNSAERTNREEKLNRGNEDVNGDEDDDEDEDDA
NYEEDDEDGYVEDDDINRLVYLDERESRYENADVEYGTIFSTKSFSVTGCLNHDFPKK
LSLKCGNKNQSSNDSKWAPATQLVSRKRYIKDSLRCIKPLTEDHPWVGKIIFKPALPP
AFETNNPPIRVYSGEDSTDLMHVKNHYLKPYIVGSCGFLKTGSKLFHFYDRTNDLTNL
"
gene complement(356794..357186)
/locus_tag="YNL143C"
/db_xref="GeneID:855579"
mRNA complement(356794..357186)
/locus_tag="YNL143C"
/product="hypothetical protein"
/transcript_id="NM_001270759.1"
/db_xref="GI:398364642"
/db_xref="GeneID:855579"
CDS complement(356794..357186)
/locus_tag="YNL143C"
/note="hypothetical protein; expressed at both mRNA and
protein levels"
/codon_start=1
/product="hypothetical protein"
/protein_id="NP_001257688.1"
/db_xref="GI:398364643"
/db_xref="SGD:S000005087"
/db_xref="GeneID:855579"
/translation="MREQLKLFTREIVDFTFLILSGFDYYQTLLISSNSSKKRPKDSS
LLSEKKKKKKKKKKDVLSYLSYLKDLPFVPFLFWQPGYSQREKNPRQHSLFIMTITKP
GMISMADMNYVVSKNRSLNRPAERGGNR"
gene 357453..358952
/gene="MEP2"
/locus_tag="YNL142W"
/db_xref="GeneID:855580"
mRNA 357453..358952
/gene="MEP2"
/locus_tag="YNL142W"
/product="Mep2p"
/transcript_id="NM_001182980.1"
/db_xref="GI:296147626"
/db_xref="GeneID:855580"
CDS 357453..358952
/gene="MEP2"
/locus_tag="YNL142W"
/note="Ammonium permease involved in regulation of
pseudohyphal growth; belongs to a ubiquitous family of
cytoplasmic membrane proteins that transport only ammonium
(NH4+); expression is under the nitrogen catabolite
repression regulation"
/codon_start=1
/product="Mep2p"
/protein_id="NP_014257.1"
/db_xref="GI:6324187"
/db_xref="SGD:S000005086"
/db_xref="GeneID:855580"
/translation="MSYNFTGTPTGEGTGGNSLTTDLNTQFDLANMGWIGVASAGVWI
MVPGIGLLYSGLSRKKHALSLLWASMMASAVCIFQWFFWGYSLAFSHNTRGNGFIGTL
EFFGFRNVLGAPSSVSSLPDILFAVYQGMFAAVTGALMLGGACERARLFPMMVFLFLW
MTIVYCPIACWVWNAEGWLVKLGSLDYAGGLCVHLTSGHGGLVYALILGKRNDPVTRK
GMPKYKPHSVTSVVLGTVFLWFGWMFFNGGSAGNATIRAWYSIMSTNLAAACGGLTWM
VIDYFRCGRKWTTVGLCSGIIAGLVGITPAAGFVPIWSAVVIGVVTGAGCNLAVDLKS
LLRIDDGLDCYSIHGVGGCIGSVLTGIFAADYVNATAGSYISPIDGGWINHHYKQVGY
QLAGICAALAWTVTVTSILLLTMNAIPFLKLRLSADEEELGTDAAQIGEFTYEESTAY
IPEPIRSKTSAQMPPPHENIDDKIVGNTDAEKNSTPSDASSTKNTDHIV"
gene 359596..360639
/gene="AAH1"
/locus_tag="YNL141W"
/db_xref="GeneID:855581"
mRNA 359596..360639
/gene="AAH1"
/locus_tag="YNL141W"
/product="adenine deaminase"
/transcript_id="NM_001182979.1"
/db_xref="GI:296147627"
/db_xref="GeneID:855581"
CDS 359596..360639
/gene="AAH1"
/locus_tag="YNL141W"
/EC_number="3.5.4.2"
/note="Adenine deaminase (adenine aminohydrolase),
converts adenine to hypoxanthine; involved in purine
salvage; transcriptionally regulated by nutrient levels
and growth phase; Aah1p degraded upon entry into
quiescence via SCF and the proteasome"
/codon_start=1
/product="adenine deaminase"
/protein_id="NP_014258.1"
/db_xref="GI:6324188"
/db_xref="SGD:S000005085"
/db_xref="GeneID:855581"
/translation="MVSVEFLQELPKCEHHLHLEGTLEPDLLFPLAKRNDIILPEGFP
KSVEELNEKYKKFRDLQDFLDYYYIGTNVLISEQDFFDLAWAYFKKVHKQGLVHAEVF
YDPQSHTSRGISIETVTKGFQRACDKAFSEFGITSKLIMCLLRHIEPEECLKTIEEAT
PFIKDGTISALGLDSAEKPFPPHLFVECYGKAASLNKDLKLTAHAGEEGPAQFVSDAL
DLLQVTRIDHGINSQYDEELLDRLSRDQTMLTICPLSNVKLQVVQSVSELPLQKFLDR
DVPFSLNSDDPAYFGGYILDVYTQVSKDFPHWDHETWGRIAKNAIKGSWCDDKRKNGL
LSRVDEVVTKYSH"
gene complement(360917..361486)
/locus_tag="YNL140C"
/db_xref="GeneID:855582"
mRNA complement(360917..361486)
/locus_tag="YNL140C"
/product="hypothetical protein"
/transcript_id="NM_001270760.1"
/db_xref="GI:398364662"
/db_xref="GeneID:855582"
CDS complement(360917..361486)
/locus_tag="YNL140C"
/note="hypothetical protein; expressed at both mRNA and
protein levels; partially overlaps THO2/YNL139C"
/codon_start=1
/product="hypothetical protein"
/protein_id="NP_001257689.1"
/db_xref="GI:398364663"
/db_xref="SGD:S000005084"
/db_xref="GeneID:855582"
/translation="MLEAKMVMVVPTIEDQAMIVLHPKILSQSVVMHIKGQNYQLDLV
KVKHIMIEVGHLDPQVRTGAMVLIKGITAYVKSIRKTVHNVHNYGFLKSHFKRAKTAA
KPTLTKLHLTSATRLQKMKKSRIKDSRRMKQLETNFKRKIIEIHEIAVLPIEPMKIKG
TTEIERAILRRFRKVPRVGITSVGTRGNY"
gene complement(360924..365717)
/gene="THO2"
/locus_tag="YNL139C"
/gene_synonym="LDB5; RLR1; ZRG13"
/db_xref="GeneID:855583"
mRNA complement(360924..365717)
/gene="THO2"
/locus_tag="YNL139C"
/gene_synonym="LDB5; RLR1; ZRG13"
/product="Tho2p"
/transcript_id="NM_001182977.3"
/db_xref="GI:398364666"
/db_xref="GeneID:855583"
CDS complement(360924..365717)
/gene="THO2"
/locus_tag="YNL139C"
/gene_synonym="LDB5; RLR1; ZRG13"
/note="Subunit of the THO complex, which is required for
efficient transcription elongation and involved in
transcriptional elongation-associated recombination;
required for LacZ RNA expression from certain plasmids"
/codon_start=1
/product="Tho2p"
/protein_id="NP_014260.3"
/db_xref="GI:398364667"
/db_xref="SGD:S000005083"
/db_xref="GeneID:855583"
/translation="MAEQTLLSKLNALSQKVIPPASPSQASILTEEVIRNWPERSKTL
CSDFTALESNDEKEDWLRTLFIELFDFINKNDENSPLKLSDVASFTNELVNHERQVSQ
ASIVGKMFIAVSSTVPNINDLTTISLCKLIPSLHEELFKFSWISSKLLNKEQTTLLRH
LLKKSKYELKKYNLLVENSVGYGQLVALLILAYYDPDNFSKVSAYLKEIYHIMGKYSL
DSIRTLDVILNVSSQFITEGYKFFIALLRKSDSWPSSHVANNSNYSSLNEGGNMIAAN
IISFNLSQYNEEVDKENYERYMDMCCILLKNGFVNFYSIWDNVKPEMEFLQEYIQNLE
TELEEESTKGVENPLAMAAALSTENETDEDNALVVNDDVNMKDKISEETNADIESKGK
QKTQQDILLFGKIKLLERLLIHGCVIPVIHVLKQYPKVLYVSESLSRYLGRVFEYLLN
PLYTSMTSSGESKDMATALMITRIDNGILAHKPRLIHKYKTHEPFESLELNSSYVFYY
SEWNSNLTPFASVNDLFENSHIYLSIIGPYLGRIPTLLSKISRIGVADIQKNHGSESL
HVTIDKWIDYVRKFIFPATSLLQNNPIATSEVYELMKFFPFEKRYFIYNEMMTKLSQD
ILPLKVSFNKAEREAKSILKALSIDTIAKESRRFAKLISTNPLASLVPAVKQIENYDK
VSELVVYTTKYFNDFAYDVLQFVLLLRLTYNRPAVQFDGVNQAMWVQRLSIFIAGLAK
NCPNMDISNIITYILKTLHNGNIIAVSILKELIITVGGIRDLNEVNMKQLLMLNSGSP
LKQYARHLIYDFRDDNSVISSRLTSFFTDQSAISEIILLLYTLNLKANTQNSHYKILS
TRCDEMNTLLWSFIELIKHCLKGKAFEENVLPFVELNNRFHLSTPWTFHIWRDYLDNQ
LNSNENFSIDELIEGAEFSDVDLTKISKDLFTTFWRLSLYDIHFDKSLYDERKNALSG
ENTGHMSNRKKHLIQNQIKDILVTGISHQRAFKKTSEFISEKSNVWNKDCGEDQIKIF
LQNCVVPRVLFSPSDALFSSFFIFMAFRTENLMSILNTCITSNILKTLLFCCTSSEAG
NLGLFFTDVLKKLEKMRLNGDFNDQASRKLYEWHSVITEQVIDLLSEKNYMSIRNGIE
FMKHVTSVFPVVKAHIQLVYTTLEENLINEEREDIKLPSSALIGHLKARLKDALELDE
FCTLTEEEAEQKRIREMELEEIKNYETACQNEQKQVALRKQLELNKSQRLQNDPPKSV
ASGSAGLNSKDRYTYSRNEPVIPTKPSSSQWSYSKVTRHVDDINHYLATNHLQKAISL
VENDDETRNLRKLSKQNMPIFDFRNSTLEIFERYFRTLIQNPQNPDFAEKIDSLKRYI
KNISREPYPDTTSSYSEAAAPEYTKRSSRYSGNAGGKDGYGSSNYRGPSNDRSAPKNI
KPISSYAHKRSELPTRPSKSKTYNDRSRALRPTGPDRGDGFDQRDNRLREEYKKNSSQ
RSQLRFPEKPFQEGKDSSKANPYQASSYKRDSPSENEEKPNKRFKKDETIRNKFQTQD
YRNTRDSGAAHRANENQRYNGNRKSNTQALPQGPKGGNYVSRYQR"
gene 366033..366412
/gene="YSF3"
/locus_tag="YNL138W-A"
/gene_synonym="RCP10"
/db_xref="GeneID:1466511"
mRNA join(366033..366035,366158..366412)
/gene="YSF3"
/locus_tag="YNL138W-A"
/gene_synonym="RCP10"
/product="Ysf3p"
/transcript_id="NM_001184519.1"
/db_xref="GI:296147629"
/db_xref="GeneID:1466511"
CDS join(366033..366035,366158..366412)
/gene="YSF3"
/locus_tag="YNL138W-A"
/gene_synonym="RCP10"
/note="Component of the SF3b subcomplex of the U2 snRNP,
essential protein required for for splicing and for
assembly of SF3b"
/codon_start=1
/product="Ysf3p"
/protein_id="NP_878153.1"
/db_xref="GI:33438865"
/db_xref="SGD:S000028509"
/db_xref="GeneID:1466511"
/translation="MAEKQRQLKLQKIYKQKYIGLGDESTTREQWQRNVRNDTLNTLQ
GHSASLEYVSLSRGDLSIRDTRIHLLKSMSPGYKAYLREER"
gene 366741..368321
/gene="SRV2"
/locus_tag="YNL138W"
/gene_synonym="CAP"
/db_xref="GeneID:855584"
mRNA 366741..368321
/gene="SRV2"
/locus_tag="YNL138W"
/gene_synonym="CAP"
/product="Srv2p"
/transcript_id="NM_001182976.1"
/db_xref="GI:296147630"
/db_xref="GeneID:855584"
CDS 366741..368321
/gene="SRV2"
/locus_tag="YNL138W"
/gene_synonym="CAP"
/note="CAP (cyclase-associated protein) subunit of
adenylyl cyclase complex; N-terminus binds adenylyl
cyclase and facilitates activation by RAS; C-terminus
binds ADP-actin monomers, facilitating regulation of actin
dynamics and cell morphogenesis"
/codon_start=1
/product="Srv2p"
/protein_id="NP_014261.1"
/db_xref="GI:6324191"
/db_xref="SGD:S000005082"
/db_xref="GeneID:855584"
/translation="MPDSKYTMQGYNLVKLLKRLEEATARLEDVTIYQEGYIQNKLEA
SKNNKPSDSGADANTTNEPSAENAPEVEQDPKCITAFQSYIGENIDPLVELSGKIDTV
VLDALQLLKGGFQSQLTFLRAAVRSRKPDYSSQTFADSLRPINENIIKLGQLKESNRQ
SKYFAYLSALSEGAPLFSWVAVDTPVSMVTDFKDAAQFWTNRILKEYRESDPNAVEWV
KKFLASFDNLKAYIKEYHTTGVSWKKDGMDFADAMAQSTKNTGATSSPSPASATAAPA
PPPPPPAPPASVFEISNDTPATSSDANKGGIGAVFAELNQGENITKGLKKVDKSQQTH
KNPELRQSSTVSSTGSKSGPPPRPKKPSTLKTKRPPRKELVGNKWFIENYENETESLV
IDANKDESIFIGKCSQVLVQIKGKVNAISLSETESCSVVLDSSISGMDVIKSNKFGIQ
VNHSLPQISIDKSDGGNIYLSKESLNTEIYTSCSTAINVNLPIGEDDDYVEFPIPEQM
KHSFADGKFKSAVFEHAG"
gene complement(368595..370055)
/gene="NAM9"
/locus_tag="YNL137C"
/gene_synonym="MNA6"
/db_xref="GeneID:855585"
mRNA complement(368595..370055)
/gene="NAM9"
/locus_tag="YNL137C"
/gene_synonym="MNA6"
/product="mitochondrial 37S ribosomal protein NAM9"
/transcript_id="NM_001182975.3"
/db_xref="GI:398364684"
/db_xref="GeneID:855585"
CDS complement(368595..370055)
/gene="NAM9"
/locus_tag="YNL137C"
/gene_synonym="MNA6"
/note="Mitochondrial ribosomal component of the small
subunit"
/codon_start=1
/product="mitochondrial 37S ribosomal protein NAM9"
/protein_id="NP_014262.3"
/db_xref="GI:398364685"
/db_xref="SGD:S000005081"
/db_xref="GeneID:855585"
/translation="MPRKANLLKSLARGRVRTSFNKYNLFNLYKKGGVDLKSKSLYQQ
KWTAKQETRAYHGEHLTEKRWQTVFKPKLDSVAQLDASLRGGEIKETPFLLQTFAVLE
KRLDFALFRAMFASSVRQARQFILHGNVRVNGVKIKHPSYTLKPGDMFSVKPDKVLEA
LGAKKPSFQEALKIDKTQIVLWNKYVKEAKTEPKEVWEKKLENFEKMSDSNPKKLQFQ
EFLRQYNKNLESQQYNALKGCTQEGILRKLLNVEKEIGKSNNEPLSIDELKQGLPEIQ
DSQLLESLNNAYQEFFKSGEIRREIISKCQPDELISLATEMMNPNETTKKELSDGAKS
ALRSGKRIIAESVKLWTKNITDHFKTRMSDISDGSLTFDPKWAKNLKYHDPIKLSELE
GDEPKARKLINLPWQKNYVYGRQDPKKPFFTPWKPRPFLSPFAILPHHLEISFKTCHA
VYLRDPVARPGQSEVISPFDVPVHERAYMYYLRNGK"
gene 370368..371645
/gene="EAF7"
/locus_tag="YNL136W"
/db_xref="GeneID:855586"
mRNA 370368..371645
/gene="EAF7"
/locus_tag="YNL136W"
/product="Eaf7p"
/transcript_id="NM_001182974.1"
/db_xref="GI:296147632"
/db_xref="GeneID:855586"
CDS 370368..371645
/gene="EAF7"
/locus_tag="YNL136W"
/note="Subunit of the NuA4 histone acetyltransferase
complex, which acetylates the N-terminal tails of histones
H4 and H2A"
/codon_start=1
/product="Eaf7p"
/protein_id="NP_014263.1"
/db_xref="GI:6324193"
/db_xref="SGD:S000005080"
/db_xref="GeneID:855586"
/translation="MVVHWTIVDEIRLLRWASEFKPAGIHKHFHMFCIVERMNSPDKY
PVTLLQKETMKLGKVFTAKDIWDKLSQSYNLEKIDEMENTYSLEATTESSRNGNGNGD
DAEIHEETLLELNNRIRVRKQDFTLPWEEYGELILENARKSPNSNEEYPRVEDMNEKD
STIPKESPSTDLKNDNNKQEKNATIKVKELPEYHTEENDSPIDVQKEPIKEVQSDEKE
LQREHMSEEEQKMKSTNKTAAPVRKSQRLKRSKEVKFEDEEKEEIEEDNTKDEEQKEK
KEEIQEPKITHNEEVDKEKNENEEGDDEREKSTSYENTNGSESEGVDEGVDEELGYES
EREAEGKGKQIESEGGNLKKKTENKKGDDQQDDTKKDSKDKNEPLAKRTRHSSSTGNT
SNETSPKRKRRKAGSRKNSPPATRVSSRLRNKK"
gene complement(371882..372226)
/gene="FPR1"
/locus_tag="YNL135C"
/gene_synonym="FKB1; RBP1"
/db_xref="GeneID:855587"
mRNA complement(371882..372226)
/gene="FPR1"
/locus_tag="YNL135C"
/gene_synonym="FKB1; RBP1"
/product="peptidylprolyl isomerase FPR1"
/transcript_id="NM_001182973.1"
/db_xref="GI:296147633"
/db_xref="GeneID:855587"
CDS complement(371882..372226)
/gene="FPR1"
/locus_tag="YNL135C"
/gene_synonym="FKB1; RBP1"
/EC_number="5.2.1.8"
/note="Peptidyl-prolyl cis-trans isomerase (PPIase), binds
to the drugs FK506 and rapamycin; also binds to the
nonhistone chromatin binding protein Hmo1p and may
regulate its assembly or function"
/codon_start=1
/product="peptidylprolyl isomerase FPR1"
/protein_id="NP_014264.1"
/db_xref="GI:6324194"
/db_xref="SGD:S000005079"
/db_xref="GeneID:855587"
/translation="MSEVIEGNVKIDRISPGDGATFPKTGDLVTIHYTGTLENGQKFD
SSVDRGSPFQCNIGVGQVIKGWDVGIPKLSVGEKARLTIPGPYAYGPRGFPGLIPPNS
TLVFDVELLKVN"
gene complement(372451..373581)
/locus_tag="YNL134C"
/db_xref="GeneID:855588"
mRNA complement(372451..373581)
/locus_tag="YNL134C"
/product="hypothetical protein"
/transcript_id="NM_001182972.3"
/db_xref="GI:398364702"
/db_xref="GeneID:855588"
CDS complement(372451..373581)
/locus_tag="YNL134C"
/note="hypothetical protein; has similarity to
dehydrogenases from other model organisms; green
fluorescent protein (GFP)-fusion protein localizes to both
the cytoplasm and nucleus; protein abundance increases in
response to DNA replication stress"
/codon_start=1
/product="hypothetical protein"
/protein_id="NP_014265.3"
/db_xref="GI:398364703"
/db_xref="SGD:S000005078"
/db_xref="GeneID:855588"
/translation="MSASIPETMKAVVIENGKAVVKQDIPIPELEEGFVLIKTVAVAG
NPTDWKHIDFKIGPQGALLGCDAAGQIVKLGPNVDAARFAIGDYIYGVIHGASVRFPS
NGAFAEYSAISSETAYKPAREFRLCGKDKLPEGPVKSLEGAVSLPVSLTTAGMILTHS
FGLDMTWKPSKAQRDQPILFWGGATAVGQMLIQLAKKLNGFSKIIVVASRKHEKLLKE
YGADELFDYHDADVIEQIKKKYNNIPYLVDCVSNTETIQQVYKCAADDLDATVVQLTV
LTEKDIKEEDRRQNVSIEGTLLYLIGGNDVPFGTFTLPADPEYKEAAIKFIKFINPKI
NDGEIHHIPVKVYKNGLDDIPQLLDDIKHGRNSGEKLVAVLK"
gene complement(374171..374692)
/gene="FYV6"
/locus_tag="YNL133C"
/db_xref="GeneID:855589"
mRNA complement(374171..374692)
/gene="FYV6"
/locus_tag="YNL133C"
/product="Fyv6p"
/transcript_id="NM_001182971.3"
/db_xref="GI:398364708"
/db_xref="GeneID:855589"
CDS complement(374171..374692)
/gene="FYV6"
/locus_tag="YNL133C"
/note="hypothetical protein, required for survival upon
exposure to K1 killer toxin; proposed to regulate
double-strand break repair via non-homologous end-joining"
/codon_start=1
/product="Fyv6p"
/protein_id="NP_014266.3"
/db_xref="GI:398364709"
/db_xref="SGD:S000005077"
/db_xref="GeneID:855589"
/translation="MSSTSDNNANSAREKKPLKFVSEGVGNVEAQRIREQVEQKKYEA
EYKRKTRKSLRDQLRSNAISKQKQYNGLVRDRESFTRLSKEDLEFYQKSKNELLKKEK
ELNNYLDVKAINFEKKKKALLMENDSTTNTEKYLETGTSLGSKTQIKGVKTSSPKPKI
KVSIKKLGRKLEN"
gene 374869..374959
/locus_tag="tF(GAA)N"
/db_xref="GeneID:855590"
tRNA join(374869..374905,374924..374959)
/locus_tag="tF(GAA)N"
/product="tRNA-Phe"
/note="Phenylalanine tRNA (tRNA-Phe), predicted by
tRNAscan-SE analysis"
/db_xref="SGD:S000006569"
/db_xref="GeneID:855590"
gene 375321..378491
/gene="KRE33"
/locus_tag="YNL132W"
/db_xref="GeneID:855591"
mRNA 375321..378491
/gene="KRE33"
/locus_tag="YNL132W"
/product="Kre33p"
/transcript_id="NM_001182970.1"
/db_xref="GI:296147636"
/db_xref="GeneID:855591"
CDS 375321..378491
/gene="KRE33"
/locus_tag="YNL132W"
/note="Essential protein, required for biogenesis of the
small ribosomal subunit; heterozygous mutant shows
haploinsufficiency in K1 killer toxin resistance"
/codon_start=1
/product="Kre33p"
/protein_id="NP_014267.1"
/db_xref="GI:6324197"
/db_xref="SGD:S000005076"
/db_xref="GeneID:855591"
/translation="MAKKAIDSRIPSLIRNGVQTKQRSIFVIVGDRARNQLPNLHYLM
MSADLKMNKSVLWAYKKKLLGFTSHRKKRENKIKKEIKRGTREVNEMDPFESFISNQN
IRYVYYKESEKILGNTYGMCILQDFEALTPNLLARTIETVEGGGIVVILLKSMSSLKQ
LYTMTMDVHARYRTEAHGDVVARFNERFILSLGSNPNCLVVDDELNVLPLSGAKNVKP
LPPKEDDELPPKQLELQELKESLEDVQPAGSLVSLSKTVNQAHAILSFIDAISEKTLN
FTVALTAGRGRGKSAALGISIAAAVSHGYSNIFVTSPSPENLKTLFEFIFKGFDALGY
QEHIDYDIIQSTNPDFNKAIVRVDIKRDHRQTIQYIVPQDHQVLGQAELVVIDEAAAI
PLPIVKNLLGPYLVFMASTINGYEGTGRSLSLKLIQQLRNQNNTSGRESTQTAVVSRD
NKEKDSHLHSQSRQLREISLDEPIRYAPGDPIEKWLNKLLCLDVTLIKNPRFATRGTP
HPSQCNLFVVNRDTLFSYHPVSENFLEKMMALYVSSHYKNSPNDLQLMSDAPAHKLFV
LLPPIDPKDGGRIPDPLCVIQIALEGEISKESVRNSLSRGQRAGGDLIPWLISQQFQD
EEFASLSGARIVRIATNPEYASMGYGSRAIELLRDYFEGKFTDMSEDVRPKDYSIKRV
SDKELAKTNLLKDDVKLRDAKTLPPLLLKLSEQPPHYLHYLGVSYGLTQSLHKFWKNN
SFVPVYLRQTANDLTGEHTCVMLNVLEGRESNWLVEFAKDFRKRFLSLLSYDFHKFTA
VQALSVIESSKKAQDLSDDEKHDNKELTRTHLDDIFSPFDLKRLDSYSNNLLDYHVIG
DMIPMLALLYFGDKMGDSVKLSSVQSAILLAIGLQRKNIDTIAKELNLPSNQTIAMFA
KIMRKMSQYFRQLLSQSIEETLPNIKDDAIAEMDGEEIKNYNAAEALDQMEEDLEEAG
SEAVQAMREKQKELINSLNLDKYAINDNSEEWAESQKSLEIAAKAKGVVSLKTGKKRT
TEKAEDIYRQEMKAMKKPRKSKKAAN"
gene 378767..379225
/gene="TOM22"
/locus_tag="YNL131W"
/gene_synonym="MAS17; MAS22; MOM22"
/db_xref="GeneID:855592"
mRNA 378767..379225
/gene="TOM22"
/locus_tag="YNL131W"
/gene_synonym="MAS17; MAS22; MOM22"
/product="Tom22p"
/transcript_id="NM_001182969.1"
/db_xref="GI:296147637"
/db_xref="GeneID:855592"
CDS 378767..379225
/gene="TOM22"
/locus_tag="YNL131W"
/gene_synonym="MAS17; MAS22; MOM22"
/note="Component of the TOM (translocase of outer
mitochondrial membrane) complex responsible for initial
import of mitochondrially directed proteins; acts as a
receptor for precursor proteins and mediates interaction
between TOM and TIM complexes"
/codon_start=1
/product="Tom22p"
/protein_id="NP_014268.1"
/db_xref="GI:6324198"
/db_xref="SGD:S000005075"
/db_xref="GeneID:855592"
/translation="MVELTEIKDDVVQLDEPQFSRNQAIVEEKASATNNDVVDDEDDS
DSDFEDEFDENETLLDRIVALKDIVPPGKRQTISNFFGFTSSFVRNAFTKSGNLAWTL
TTTALLLGVPLSLSILAEQQLIEMEKTFDLQSDANNILAQGEKDAAATAN"
gene complement(379558..380831)
/gene="CPT1"
/locus_tag="YNL130C"
/db_xref="GeneID:855593"
mRNA complement(join(379558..380689,380782..380831))
/gene="CPT1"
/locus_tag="YNL130C"
/product="diacylglycerol cholinephosphotransferase"
/transcript_id="NM_001182968.3"
/db_xref="GI:398364722"
/db_xref="GeneID:855593"
CDS complement(join(379558..380689,380782..380831))
/gene="CPT1"
/locus_tag="YNL130C"
/EC_number="2.7.8.2"
/note="Cholinephosphotransferase; required for
phosphatidylcholine biosynthesis and for
inositol-dependent regulation of EPT1 transcription; CPT1
has a paralog, EPT1, that arose from the whole genome
duplication"
/codon_start=1
/product="diacylglycerol cholinephosphotransferase"
/protein_id="NP_014269.4"
/db_xref="GI:398364723"
/db_xref="SGD:S000005074"
/db_xref="GeneID:855593"
/translation="MGFFIPQSSLGNLKLYKYQSDDRSFLSNHVLRPFWRKFATIFPL
WMAPNLVTLLGFCFIIFNVLTTLYYDPYFDQESPRWTYFSYAIGLFLYQTFDACDGMH
ARRTGQQGPLGELFDHCIDSINTTLSMIPVCSMTGMGYTYMTIFSQFAILCSFYLSTW
EEYHTHKLYLAEFCGPVEGIIVLCISFIAVGIYGPQTIWHTKVAQFSWQDFVFDVETV
HLMYAFCTGALIFNIVTAHTNVVRYYESQSTKSATPSKTAENISKAVNGLLPFFAYFS
SIFTLVLIQPSFISLALILSIGFSVAFVVGRMIIAHLTMQPFPMVNFPFLIPTIQLVL
YAFMVYVLDYQKGSIVSALVWMGLGLTLAIHGMFINDIIYDITTFLDIYALSIKHPKE
I"
gene complement(381245..381391)
/gene="DGR1"
/locus_tag="YNL130C-A"
/db_xref="GeneID:1466512"
mRNA complement(381245..381391)
/gene="DGR1"
/locus_tag="YNL130C-A"
/product="Dgr1p"
/transcript_id="NM_001184574.1"
/db_xref="GI:296147639"
/db_xref="GeneID:1466512"
CDS complement(381245..381391)
/gene="DGR1"
/locus_tag="YNL130C-A"
/note="hypothetical protein; dgr1 null mutant is resistant
to 2-deoxy-D-glucose"
/codon_start=1
/product="Dgr1p"
/protein_id="NP_878154.1"
/db_xref="GI:33438866"
/db_xref="SGD:S000028579"
/db_xref="GeneID:1466512"
/translation="MQVGFVSQTNCRSFPACIVFLFQMSQRQRSFNANLRVFKSKCKK
IYIG"
gene 381480..382202
/gene="NRK1"
/locus_tag="YNL129W"
/db_xref="GeneID:855594"
mRNA 381480..382202
/gene="NRK1"
/locus_tag="YNL129W"
/product="ribosylnicotinamide kinase"
/transcript_id="NM_001182967.1"
/db_xref="GI:296147640"
/db_xref="GeneID:855594"
CDS 381480..382202
/gene="NRK1"
/locus_tag="YNL129W"
/EC_number="2.7.1.22"
/note="Nicotinamide riboside kinase, catalyzes the
phosphorylation of nicotinamide riboside and nicotinic
acid riboside in salvage pathways for NAD+ biosynthesis"
/codon_start=1
/product="ribosylnicotinamide kinase"
/protein_id="NP_014270.1"
/db_xref="GI:6324200"
/db_xref="SGD:S000005073"
/db_xref="GeneID:855594"
/translation="MTSKKVILVALSGCSSSGKTTIAKLTASLFTKATLIHEDDFYKH
DNEVPVDAKYNIQNWDSPEALDFKLFGKELDVIKQTGKIATKLIHNNNVDDPFTKFHI
DRQVWDELKAKYDSINDDKYEVVIVDGFMIFNNTGISKKFDLKILVRAPYEVLKKRRA
SRKGYQTLDSFWVDPPYYFDEFVYESYRANHAQLFVNGDVEGLLDPRKSKNIKEFIND
DDTPIAKPLSWVCQEILKLCKD"
gene 382359..383663
/gene="TEP1"
/locus_tag="YNL128W"
/db_xref="GeneID:855595"
mRNA 382359..383663
/gene="TEP1"
/locus_tag="YNL128W"
/product="Tep1p"
/transcript_id="NM_001182966.4"
/db_xref="GI:398364734"
/db_xref="GeneID:855595"
CDS 382359..383663
/gene="TEP1"
/locus_tag="YNL128W"
/EC_number="3.1.3.67"
/note="PTEN homolog with no demonstrated inositol lipid
phosphatase activity; plays a role in normal sporulation;
homolog of human tumor suppressor gene PTEN/MMAC1/TEP1 and
fission yeast ptn1"
/codon_start=1
/product="Tep1p"
/protein_id="NP_014271.3"
/db_xref="GI:398364735"
/db_xref="SGD:S000005072"
/db_xref="GeneID:855595"
/translation="MREEGSELEMEKGFLKWKPVNLMKKILSLPMKKTKNDIGLRLDI
SYILVNLIVCSYPVNTYPKLLYRNSLDDLILFLTVYHGKGNFRIFNFRGEKEDSDYKD
NDLIGIAAKFESKDFEIQELRSTLINDGKIPISPIDLETRTLVEEETNNVICERIGWL
DHFPPPFELLEEIVDGIENYLSVSKNRVAVLHCRMGKGRSGMITVAYLMKYLQCPLGE
ARLIFMQARFKYGMTNGVTIPSQLRYLRYHEFFITHEKAAQEGISNEAVKFKFKFRLA
KMTFLRPSSLITSESAIVTTKIQHYNDDRNALLTRKVVYSDIMAHECGGNMTFIFGRD
YLTLENDCRIEFTLGTSKSKAASSIISWTSCASCWLNIYLETLMHIIKDDSSPDYFQV
ERLKRDEMLGTTISWQELDGFGELSTHGLKLFQALKLEWEII"
gene 383987..386848
/gene="FAR11"
/locus_tag="YNL127W"
/db_xref="GeneID:855596"
mRNA 383987..386848
/gene="FAR11"
/locus_tag="YNL127W"
/product="Far11p"
/transcript_id="NM_001182965.3"
/db_xref="GI:398364736"
/db_xref="GeneID:855596"
CDS 383987..386848
/gene="FAR11"
/locus_tag="YNL127W"
/note="Protein involved in recovery from cell cycle arrest
in response to pheromone, in a Far1p-independent pathway;
interacts with Far3p, Far7p, Far8p, Far9p, and Far10p; has
similarity to the N- and C-termini of N. crassa HAM-2"
/codon_start=1
/product="Far11p"
/protein_id="NP_014272.3"
/db_xref="GI:398364737"
/db_xref="SGD:S000005071"
/db_xref="GeneID:855596"
/translation="MNASGRSHSKGPIIRSVSLEDLKRNSSFKGNLKYKDEVTSHKEP
QVGTLSNEELLKDLDNMLRGKLNMGRNSFHADKRNKSDGNISALTFKARSGLEGDIRT
IDIQQDSSDENDNFKFSDDGVNKDRNNEKDNNTDNAVEFQDDAEEAEEENEDESFANV
DELDGFDLNKVSDGKHVPINEKGEVDYNMPVDKEFQKSLDQCAASLEERSSAPYALQR
AVDWELKMFYSLEDELSEWFCSSDYMHFGQTQTLFKQKITQPQLFFDDENYAASVVEC
LIEDIPNSLASNLLALSYISMGCFAFTNSKSEHTKIIRRNNLMLVPHIQEIVHAFKKI
AISCRDDNRNLKKQTILLFHSSTILYFICSICIEGRGENPEAVNVVIDAFEKTDLLEF
LTKYIENWRWNSRLAMRIRNMISLLFKLIVLQFGDSSVYKQTKSSIYNLHGLTYPSKH
PEKLSISPLHYQAFREDITSRFPDYNMPSSGLPKDVDKSESLSQFLEIPRPKSKNPLN
MALIVPEKHIATPAPSPPSSPQLMHLGEGPRPRKSFQTNMAYPCLYPSDNEGSEDDTL
EDRIDLNIERKPDNDIVIPFSTEEAARILSESLEIKLSTKQLWYERDLFMITERGWKQ
QLENEPYDYAALNHDANSSKEEKSAICIMQRIDKYYKSCLSSFNSLVFVLLQTMESSL
TNNFHRKSEVSDKNLLNMLTPQLEIVRAKELSLKSAAGILHALLKWFKLSHILKFEHL
AVVIHDSRYINTCASILSKYSEVYPERVFNKYVQTPNSFWKECSLSNESYRESYSVDD
SGEVDTEIMPSFAYLLRILRKVTGNKTQRLKELPLSIGILFKRYYRLFNLDMYHPILK
ITRELTPFKNKRWKSEHMELISGVYLYEKLELTDNWVTGKDISGELSDACGQEIALRA
LLQFYNFQHYEISMEDLGYGHRNSSSQDLLNKESEYLNI"
gene 387227..389767
/gene="SPC98"
/locus_tag="YNL126W"
/db_xref="GeneID:855597"
mRNA 387227..389767
/gene="SPC98"
/locus_tag="YNL126W"
/product="Spc98p"
/transcript_id="NM_001182964.1"
/db_xref="GI:296147643"
/db_xref="GeneID:855597"
CDS 387227..389767
/gene="SPC98"
/locus_tag="YNL126W"
/note="Component of the microtubule-nucleating Tub4p
(gamma-tubulin) complex; interacts with Spc110p at the
spindle pole body (SPB) inner plaque and with Spc72p at
the SPB outer plaque"
/codon_start=1
/product="Spc98p"
/protein_id="NP_014273.1"
/db_xref="GI:6324203"
/db_xref="SGD:S000005070"
/db_xref="GeneID:855597"
/translation="MELEPTLFGIIEALAPQLLSQSHLQTFVSDVVNLLRSSTKSATQ
LGPLIDFYKLQSLDSPETTIMWHKIEKFLDALFGIQNTDDMVKYLSVFQSLLPSNYRA
KIVQKSSGLNMENLANHEHLLSPVRAPSIYTEASFENMDRFSERRSMVSSPNRYVPSS
TYSSVTLRQLSNPYYVNTIPEEDILKYVSYTLLATTSALFPFDHEQIQIPSKIPNFES
GLLHLIFEAGLLYQSLGYKVEKFRMLNISPMKKALIIEISEELQNYTAFVNNLVSSGT
VVSLKSLYREIYENIIRLRIYCRFTEHLEELSGDTFLIELNIFKSHGDLTIRKIATNL
FNSMISLYYEYLMNWLTKGLLRATYGEFFIAENTDTNGTDDDFIYHIPIEFNQERVPA
FIPKELAYKIFMIGKSYIFLEKYCKEVQWTNEFSKKYHVLYQSNSYRGISTNFFEIIN
DQYSEIVNHTNQILNQKFHYRDVVFALKNILLMGKSDFMDALIEKANDILATPSDSLP
NYKLTRVLQEAVQLSSLRHLMNSPRNSSVINGLDARVLDLGHGSVGWDVFTLDYILYP
PLSLVLNVNRPFGRKEYLRIFNFLWRFKKNNYFYQKEMLKSNDIIRSFKKIRGYNPLI
RDIINKLSRISILRTQFQQFNSKMESYYLNCIIEENFKEMTRKLQRTENKSQNQFDLI
RLNNGTIELNGILTPKAEVLTKSSSSKPQKHAIEKTLNIDELESVHNTFLTNILSHKL
FATNTSEISVGDYSGQPYPTSLVLLLNSVYEFVKVYCNLNDIGYEIFIKMNLNDHEAS
NGLLGKFNTNLKEIVSQYKNFKDRLYIFRADLKNDGDEELFLLSKSLR"
gene complement(390146..392167)
/gene="ESBP6"
/locus_tag="YNL125C"
/gene_synonym="MCH3"
/db_xref="GeneID:855598"
mRNA complement(390146..392167)
/gene="ESBP6"
/locus_tag="YNL125C"
/gene_synonym="MCH3"
/product="Esbp6p"
/transcript_id="NM_001182963.1"
/db_xref="GI:296147644"
/db_xref="GeneID:855598"
CDS complement(390146..392167)
/gene="ESBP6"
/locus_tag="YNL125C"
/gene_synonym="MCH3"
/note="Protein with similarity to monocarboxylate
permeases, appears not to be involved in transport of
monocarboxylates such as lactate, pyruvate or acetate
across the plasma membrane"
/codon_start=1
/product="Esbp6p"
/protein_id="NP_014274.1"
/db_xref="GI:6324204"
/db_xref="SGD:S000005069"
/db_xref="GeneID:855598"
/translation="MSTHSNDYFSASSGMVSETSSEVSSINSSQPVSFSKASIAAPVP
CSDLHSTKSNDASRKLSISRTLTNRLNDIKKAVDDDNLQTEENSADVNKILESRFDVA
DAIRLQHNESVQSKLNIPVTHTTTAGASLSAPSSSAFSASSIQNDTTEHKASMDSKLM
RNRLYPASTKHSGKDLEAQGITEFEPDEPTVKKVFTNKSTGQLELPPDGGYGWVVTFC
VFLTMFSTWGCNASFGVDLAYYLNHDTYPGASKYDYALIAGLTVFLGQLLSPLVMALM
RIIGLRTTMLFGDAVMLAAYLLASFTTKLWQLYVTQGFMVGCSISLIFVPATTVLPGW
FLKKRAVAMGVSLLGTGAGGVVYGLATNKMLSDFGNTRWCLRIIGISCSISVLVAIAL
LKERNPTPAIGLKSPRAMFEQLKAMFSLKVITKPFVVLIALWFMFALFAYNMMVFTLS
SYAISKGLSSHDASTLTAILNGSQSIGRPLMGLAGDKFGRANVTIVLTTLLTIYMFAF
WIPAHTFVQLIFFSILVGSCVGVANVMNTVLIADMVKPEEFLPAWAFVNYCGAPFLLV
CEVIAQALTVEKDKSNPYLHAQIFCGCCFIAALILISILREYSIRMKLTERQAMTNEK
LKEWKASEYDTDSADEDWGKLKERKTKYDLLLGPGIKKYFLRMVYPMKV"
gene 392892..394370
/gene="NAF1"
/locus_tag="YNL124W"
/db_xref="GeneID:855599"
mRNA 392892..394370
/gene="NAF1"
/locus_tag="YNL124W"
/product="Naf1p"
/transcript_id="NM_001182962.3"
/db_xref="GI:398364752"
/db_xref="GeneID:855599"
CDS 392892..394370
/gene="NAF1"
/locus_tag="YNL124W"
/note="RNA-binding protein required for the assembly of
box H/ACA snoRNPs and thus for pre-rRNA processing, forms
a complex with Shq1p and interacts with H/ACA snoRNP
components Nhp2p and Cbf5p; similar to Gar1p"
/codon_start=1
/product="Naf1p"
/protein_id="NP_014275.3"
/db_xref="GI:398364753"
/db_xref="SGD:S000005068"
/db_xref="GeneID:855599"
/translation="MSDDLFSKALENPDQDLNVELPKDDVDLGLLGDGGNERKTDEPV
ADAERSTGLGSGSSESESDSGSDSDSDSGSSGSEDDSADQDVEGEDEGGDAIENEDED
EDPSPSGPILSKNEILEETVPELPEDYEISEKTIITPIGVLKSAFENNIIIHATMSGE
KRVLKEGSIFCLEDRTLIGMLTEVFGPLQNPFYRIKLPDSKKNLFDELKVRLGEKAFI
VTPDAHWIDTFELKRNKGTDASNGYDEELPEEEQEFSDDEKEALFKKMKKQQRQRKKR
DNRKLANDSDNVKVKRARQPKANSLPKLVPPLGMSSNAPMQHGYKSRNARENIKRESS
ATSNRNGSSPVPITQHHQQQFSANNYPFPQQPNGMPYPPYSPFPQPTNFQYPPPPFGQ
ATPAQFSNTVPYGSLPPAYNNMSPPTQQSFMPMTQSQPPLPYGVPPMNQMQNPMYIQP
PPQAPPQGNGNFQQVMELHQILLQQQQQQHQYQHQHQQDPRT"
gene 394685..397678
/gene="NMA111"
/locus_tag="YNL123W"
/gene_synonym="YNM3"
/db_xref="GeneID:855600"
mRNA 394685..397678
/gene="NMA111"
/locus_tag="YNL123W"
/gene_synonym="YNM3"
/product="Nma111p"
/transcript_id="NM_001182961.1"
/db_xref="GI:296147646"
/db_xref="GeneID:855600"
CDS 394685..397678
/gene="NMA111"
/locus_tag="YNL123W"
/gene_synonym="YNM3"
/note="Serine protease and general molecular chaperone;
involved in response to heat stress and promotion of
apoptosis; may contribute to lipid homeostasis; sequence
similarity to the mammalian Omi/HtrA2 family of serine
proteases"
/codon_start=1
/product="Nma111p"
/protein_id="NP_014276.1"
/db_xref="GI:6324206"
/db_xref="SGD:S000005067"
/db_xref="GeneID:855600"
/translation="MTISLSNIKKRDHSKISDGTSGESSLVKRKQLESATGDQEEEYT
DHEIIIEPLHFANNNNTVLTDSENYLRWQNTISNVVKSVVSIHFSQVAPFDCDSALVS
EATGFVVDAKLGIILTNRHVVGPGPFVGYVVFDNHEECDVIPIYRDPVHDFGFLKFDP
KNIKYSKIKALTLKPSLAKVGSEIRVVGNDAGEKLSILAGFISRIDRNAPEYGELTYN
DFNTEYIQAAASASGGSSGSPVVNIDGYAVALQAGGSTEASTDFFLPLDRILRALICI
QTNKPITRGTIQVQWLLKPYDECRRLGLTSERESEARAKFPENIGLLVAETVLREGPG
YDKIKEGDTLISINGETISSFMQVDKIQDENVGKEIQLVIQRGGVECTVTCTVGDLHA
ITPHRYVEVCGATFHELSYQMARFYALPVRGVFLSSASGSFNFDSKERVGWIVDSIDN
KETPDLDTFIEIMKTIPDRKRVTVRYHHLTDQHSPLVTSIYIDRHWCNEFRVYTRNDT
TGIWDYKNVADPLPADALKPRSAKIIPIPVNNEKVAKLSSSLCTVATMAAVPLDSLSA
DILKTSGLIIDAEKGYVLVSRRVVPHDCLDTFVTIADSLVVPATVEFLHPTHNFAIVK
YDPELVKAPLITPKLSTTRMKRGDKLQFIGFTQNDRIVTSETTVTDISSVSIPSNLIP
RYRATNLEAISIDCNVSTRCNSGILTDNDGTVRGLWLPFLGERLENKEKVYLMGLDIM
DCREVIDILKNGGKPRVSIVDAGFGSISVLQARIRGVPEEWIMRMEHESNNRLQFITV
SRVSYTEDKIHLETGDVILSVNGKLVTEMNDLNGVVSSADGILPSAMLDFKVVRDGNI
VDLKIKTVEVQETDRFVIFAGSILQKPHHAVLQAMVDVPKGVYCTFRGESSPALQYGI
SATNFITHVNEIETPDLDTFLKVVKTIPDNSYCKMRLMTFDNVPFAISLKTNYHYFPT
AELKRDNITHKWIEKEFTGNSQSEK"
gene complement(398023..398370)
/locus_tag="YNL122C"
/db_xref="GeneID:855601"
mRNA complement(398023..398370)
/locus_tag="YNL122C"
/product="hypothetical protein"
/transcript_id="NM_001182960.1"
/db_xref="GI:296147647"
/db_xref="GeneID:855601"
CDS complement(398023..398370)
/locus_tag="YNL122C"
/note="hypothetical protein; green fluorescent protein
(GFP)-fusion protein localizes to mitochondria; YNL122C is
not an essential gene"
/codon_start=1
/product="hypothetical protein"
/protein_id="NP_014277.1"
/db_xref="GI:6324207"
/db_xref="SGD:S000005066"
/db_xref="GeneID:855601"
/translation="MKISLHNKRQRGDQNQNMSVFNVLKPLLKGSNSFKVKLNGFLFN
NVSTITIRTLMKTHKGTAKRWRRTGNTFKRGIAGRKHGNIGWSHRSLKALTGRKIAHP
AYSKHLKRLLPYH"
gene complement(398684..400537)
/gene="TOM70"
/locus_tag="YNL121C"
/gene_synonym="MAS70; MOM72; OMP1"
/db_xref="GeneID:855602"
mRNA complement(398684..400537)
/gene="TOM70"
/locus_tag="YNL121C"
/gene_synonym="MAS70; MOM72; OMP1"
/product="Tom70p"
/transcript_id="NM_001182959.3"
/db_xref="GI:398364772"
/db_xref="GeneID:855602"
CDS complement(398684..400537)
/gene="TOM70"
/locus_tag="YNL121C"
/gene_synonym="MAS70; MOM72; OMP1"
/note="Component of the TOM (translocase of outer
membrane) complex responsible for recognition and initial
import steps for all mitochondrially directed proteins;
acts as a receptor for incoming precursor proteins"
/codon_start=1
/product="Tom70p"
/protein_id="NP_014278.3"
/db_xref="GI:398364773"
/db_xref="SGD:S000005065"
/db_xref="GeneID:855602"
/translation="MKSFITRNKTAILATVAATGTAIGAYYYYNQLQQQQQRGKKNTI
NKDEKKDTKDSQKETEGAKKSTAPSNPPIYPVSSNGEPDFSNKANFTAEEKDKYALAL
KDKGNQFFRNKKYDDAIKYYNWALELKEDPVFYSNLSACYVSVGDLKKVVEMSTKALE
LKPDYSKVLLRRASANEGLGKFADAMFDLSVLSLNGDFNDASIEPMLERNLNKQAMSK
LKEKFGDIDTATATPTELSTQPAKERKDKQENLPSVTSMASFFGIFKPELTFANYDES
NEADKELMNGLSNLYKRSPESYDKADESFTKAARLFEEQLDKNNEDEKLKEKLAISLE
HTGIFKFLKNDPLGAHEDIKKAIELFPRVNSYIYMALIMADRNDSTEYYNYFDKALKL
DSNNSSVYYHRGQMNFILQNYDQAGKDFDKAKELDPENIFPYIQLACLAYRENKFDDC
ETLFSEAKRKFPEAPEVPNFFAEILTDKNDFDKALKQYDLAIELENKLDGIYVGIAPL
VGKATLLTRNPTVENFIEATNLLEKASKLDPRSEQAKIGLAQMKLQQEDIDEAITLFE
ESADLARTMEEKLQAITFAEAAKVQQRIRSDPVLAKKIQETLAKLREQGLM"
gene 401040..402521
/gene="NCS2"
/locus_tag="YNL119W"
/gene_synonym="TUC2"
/db_xref="GeneID:855603"
mRNA 401040..402521
/gene="NCS2"
/locus_tag="YNL119W"
/gene_synonym="TUC2"
/product="Ncs2p"
/transcript_id="NM_001182957.3"
/db_xref="GI:398364776"
/db_xref="GeneID:855603"
CDS 401040..402521
/gene="NCS2"
/locus_tag="YNL119W"
/gene_synonym="TUC2"
/note="Protein required for thiolation of the uridine at
the wobble position of Lys(UUU) and Glu(UUC) tRNAs; has a
role in urmylation and in invasive and pseudohyphal
growth; inhibits replication of Brome mosaic virus in S.
cerevisiae"
/codon_start=1
/product="Ncs2p"
/protein_id="NP_014280.3"
/db_xref="GI:398364777"
/db_xref="SGD:S000005063"
/db_xref="GeneID:855603"
/translation="MECQRCPASARNPATVESRKEKFCDECFIKFVSTKQRKQMMKDE
YFRNLFKVIYPFEKEGSVSKILLPLSHSDSGSLVMLDIVHDLLLEQTKQHNNRTGFTV
DVLTVFTEENVSVIKERMESLINEKMSQLNKISNIFNVHFIDVNEFFNNASEVSTFII
DNENFEIFSKSKSVDDSNILTLKEILGKYCLNNSSRSDLISIIKTQLIKHFAYENGYN
AIMWGHSMTKLSEVIISLVVKGKGSQIATFLDSESFDTLNNKPCKYKNLYPMKDLLSV
EIESFLQIRNLAQFLINVEETNVKPNCLIARKSLPSLGQQKLVKNMTINEITNKYFQD
IQNDYSNIISTVLRTADKLTQPKSSMAKPSQCQICQSKIYTNPSNWLNRITVTSPYPV
ETTEEKYLFKQWQDSKLGQSHTHYVELLNEIKQGASNSLDVEDGDVKLCYGCLILLNT
SIKDKNLVWPKVDTMDITANATNKNKELSQILDQFEINSDGEE"
gene complement(402652..405564)
/gene="DCP2"
/locus_tag="YNL118C"
/gene_synonym="PSU1"
/db_xref="GeneID:855605"
mRNA complement(402652..405564)
/gene="DCP2"
/locus_tag="YNL118C"
/gene_synonym="PSU1"
/product="Dcp2p"
/transcript_id="NM_001182956.1"
/db_xref="GI:296147650"
/db_xref="GeneID:855605"
CDS complement(402652..405564)
/gene="DCP2"
/locus_tag="YNL118C"
/gene_synonym="PSU1"
/EC_number="3.-.-.-"
/note="Catalytic subunit of the Dcp1p-Dcp2p decapping
enzyme complex; removes the 5' cap structure from mRNAs
prior to their degradation; member of the Nudix hydrolase
family; forms cytoplasmic foci upon DNA replication
stress"
/codon_start=1
/product="Dcp2p"
/protein_id="NP_014281.1"
/db_xref="GI:6324211"
/db_xref="SGD:S000005062"
/db_xref="GeneID:855605"
/translation="MSLPLRHALENVTSVDRILEDLLVRFIINCPNEDLSSVERELFH
FEEASWFYTDFIKLMNPTLPSLKIKSFAQLIIKLCPLVWKWDIRVDEALQQFSKYKKS
IPVRGAAIFNENLSKILLVQGTESDSWSFPRGKISKDENDIDCCIREVKEEIGFDLTD
YIDDNQFIERNIQGKNYKIFLISGVSEVFNFKPQVRNEIDKIEWFDFKKISKTMYKSN
IKYYLINSMMRPLSMWLRHQRQIKNEDQLKSYAEEQLKLLLGITKEEQIDPGRELLNM
LHTAVQANSNNNAVSNGQVPSSQELQHLKEQSGEHNQQKDQQSSFSSQQQPSIFPSLS
EPFANNKNVIPPTMPMANVFMSNPQLFATMNGQPFAPFPFMLPLTNNSNSANPIPTPV
PPNFNAPPNPMAFGVPNMHNLSGPAVSQPFSLPPAPLPRDSGYSSSSPGQLLDILNSK
KPDSNVQSSKKPKLKILQRGTDLNSIKQNNNDETAHSNSQALLDLLKKPTSSQKIHAS
KPDTSFLPNDSVSGIQDAEYEDFESSSDEEVETARDERNSLNVDIGVNVMPSEKDSRR
SQKEKPRNDASKTNLNASAESNSVEWGPGKSSPSTQSKQNSSVGMQNKYRQEIHIGDS
DAYEVFESSSDEEDGKKLEELEQTQDNSKLISQDILKENNFQDGEVPHRDMPTESNKS
INETVGLSSTTNTVKKVPKVKILKRGETFASLANDKKAFDSSSNVSSSKDLLQMLRNP
ISSTVSSNQQSPKSQHLSGDEEIMMMLKRNSVSKPQNSEENASTSSINDANASELLGM
LKQKEKDITAPKQPYNVDSYSQKNSAKGLLNILKKNDSTGYPRTEGGPSSEMSTSMKR
NDATNNQELDKNSTELLNYLKPKPLNDGYENISNKDSSHELLNILHGNKNSSAFNNNV
YATDGYSLASDNNENSSNKLLNMLQNRSSAINEPNFDVRSNGTSGSNELLSILHRK"
gene 406358..408022
/gene="MLS1"
/locus_tag="YNL117W"
/db_xref="GeneID:855606"
mRNA 406358..408022
/gene="MLS1"
/locus_tag="YNL117W"
/product="malate synthase MLS1"
/transcript_id="NM_001182955.1"
/db_xref="GI:296147651"
/db_xref="GeneID:855606"
CDS 406358..408022
/gene="MLS1"
/locus_tag="YNL117W"
/EC_number="2.3.3.9"
/note="Malate synthase, enzyme of the glyoxylate cycle,
involved in utilization of non-fermentable carbon sources;
expression is subject to carbon catabolite repression;
localizes in peroxisomes during growth in oleic acid
medium"
/codon_start=1
/product="malate synthase MLS1"
/protein_id="NP_014282.1"
/db_xref="GI:6324212"
/db_xref="SGD:S000005061"
/db_xref="GeneID:855606"
/translation="MVKVSLDNVKLLVDVDKEPFFKPSSTTVGDILTKDALEFIVLLH
RTFNNKRKQLLENRQVVQKKLDSGSYHLDFLPETANIRNDPTWQGPILAPGLINRSTE
ITGPPLRNMLINALNAPVNTYMTDFEDSASPTWNNMVYGQVNLYDAIRNQIDFDTPRK
SYKLNGNVANLPTIIVRPRGWHMVEKHLYVDDEPISASIFDFGLYFYHNAKELIKLGK
GPYFYLPKMEHHLEAKLWNDVFCVAQDYIGIPRGTIRATVLIETLPAAFQMEEIIYQL
RQHSSGLNCGRWDYIFSTIKRLRNDPNHILPNRNQVTMTSPFMDAYVKRLINTCHRRG
VHAMGGMAAQIPIKDDPAANEKAMTKVRNDKIRELTNGHDGSWVAHPALAPICNEVFI
NMGTPNQIYFIPENVVTAANLLETKIPNGEITTEGIVQNLDIGLQYMEAWLRGSGCVP
INNLMEDAATAEVSRCQLYQWVKHGVTLKDTGEKVTPELTEKILKEQVERLSKASPLG
DKNKFALAAKYFLPEIRGEKFSEFLTTLLYDEIVSTKATPTDLSKL"
gene 408341..409909
/gene="DMA2"
/locus_tag="YNL116W"
/gene_synonym="CHF2"
/db_xref="GeneID:855607"
mRNA 408341..409909
/gene="DMA2"
/locus_tag="YNL116W"
/gene_synonym="CHF2"
/product="ubiquitin-conjugating protein DMA2"
/transcript_id="NM_001182954.3"
/db_xref="GI:398364792"
/db_xref="GeneID:855607"
CDS 408341..409909
/gene="DMA2"
/locus_tag="YNL116W"
/gene_synonym="CHF2"
/note="Ubiquitin-protein ligase (E3); controls septin
dynamics and the spindle position checkpoint (SPOC) along
with functionally redundant ligase Dma1p by regulating the
recruitment of Elm1p to the bud neck; regulates levels of
the translation initiation factor eIF2 subunit Gcd11p, as
well as abundance, localization, and ubiquitination of Cdk
inhibitory kinase Swe1p; ortholog of human RNF8 protein,
with sequence similarity to human Chfr; contains FHA and
RING finger domains"
/codon_start=1
/product="ubiquitin-conjugating protein DMA2"
/protein_id="NP_014283.3"
/db_xref="GI:398364793"
/db_xref="SGD:S000005060"
/db_xref="GeneID:855607"
/translation="MYTPIPANTPAPTAPTSSMTSNSSSASNANTTSSSGINPRNRAS
GTPSNERARPASGISSFLNTFGIRQNSQTASSSAAPDQRLFGTTPSNSHMSVAMESID
TAPQQQEPRLHHPIQMPLSAQFHVHRNYQLPISISLTAPTTTDHQQSSAHNFEGNNVG
NVQESLNQRQPNGTNNTTTSIISMAPAATTRNIVGGADGSTIVNNSQEMYKNLRHLIY
AANQPNGTEILHLDLPATSAEESNNMFNVDEVTLKQRKDKHGLFSIRLTPFIDSSSTT
NQGLFFEPIIRKAGPGSQLVIGRYTERVRDAISKIPEQYHPVVFKSKVVSRTHGCFKV
DSQGNWYIKDVKSSSGTFLNHQRLSPASSLSKDTPLRDGDILQLGMDFRGGTEEIYRC
VRMRIELNRSWKLKANSFNKEALQRLQNLQKLTTGIEEEDCSICLCKIKPCQAIFISP
CAHSWHFRCVRRLVMLSYPQFVCPNCRSSCDLEASFESSDEEDESDVESEGDQLVDQL
SVLMETSKDVDSHP"
gene complement(410119..412053)
/locus_tag="YNL115C"
/db_xref="GeneID:855608"
mRNA complement(410119..412053)
/locus_tag="YNL115C"
/product="hypothetical protein"
/transcript_id="NM_001182953.1"
/db_xref="GI:296147653"
/db_xref="GeneID:855608"
CDS complement(410119..412053)
/locus_tag="YNL115C"
/note="hypothetical protein; green fluorescent protein
(GFP)-fusion protein localizes to mitochondria; YNL115C is
not an essential gene"
/codon_start=1
/product="hypothetical protein"
/protein_id="NP_014284.1"
/db_xref="GI:6324214"
/db_xref="SGD:S000005059"
/db_xref="GeneID:855608"
/translation="MKANGLDNDPARTGMERTDIDSEHPEAQPLLNNNHRTLGAGSAN
GPAVNEGRDIESDGFIKDSLFQIRKGYRIFIHNSKWILNILILINTIWLVTTLISDFF
FNINILFGFSNRYASFNDLTLIFISIIANSFNLWFNKLGLYSALDYSLNVTLCVLTLF
NLALTYLIKYTRQRIGFVGTFTYLWTSFSFFIGAILDWYLLFYNNSINEPLEERRIDD
ANISTFNENHTNSTENRDRSQYGSGSPTPTHRSQLVQNKHTLTEWVSIGFRNTIKFLI
LIFFALFTLNTLLTTLDTYRLTHKLPITVQSPSYEAFHYVDAAKTYQLHITCYGDVFD
QENNTDLSENKKQPIILFEHGGYDTGYLSATWIEELYHLDKIQRYCLYDRPGYGLSDS
PPAPISIAMVAESLRYALIKDAKIKGPFTTVGYDLGGLFTRVFTAKNVDIVDSMMLVE
SWHEELLLKNYIQRLLPPGRGDGDDGDDGNGNDGDGRNHDKTWLPSEIERHNEFRLWW
KGIWSSLGWRLQTSWLLAHHGSKERIYGRDMKYQGRFLRSKFLESVTSSILSYRDVTN
NAESLQNVKTSIVSSKEMVKKSALWGDWQRDLTKISHKTQEWKIVEGGHEIYKYGLGK
QQTQEVLLRLIGELGKLTED"
rep_origin 412267..412496
/note="ARS1417;
Autonomously Replicating Sequence"
/db_xref="SGD:S000118386"
gene 412771..413199
/gene="RPC19"
/locus_tag="YNL113W"
/db_xref="GeneID:855609"
mRNA 412771..413199
/gene="RPC19"
/locus_tag="YNL113W"
/product="Rpc19p"
/transcript_id="NM_001182951.1"
/db_xref="GI:296147654"
/db_xref="GeneID:855609"
CDS 412771..413199
/gene="RPC19"
/locus_tag="YNL113W"
/note="RNA polymerase subunit AC19, common to RNA
polymerases I and III"
/codon_start=1
/product="Rpc19p"
/protein_id="NP_014286.1"
/db_xref="GI:6324215"
/db_xref="SGD:S000005057"
/db_xref="GeneID:855609"
/translation="MTEDIEQKKTATEVTPQEPKHIQEEEEQDVDMTGDEEQEEEPDR
EKIKLLTQATSEDGTSASFQIVEEDHTLGNALRYVIMKNPDVEFCGYSIPHPSENLLN
IRIQTYGETTAVDALQKGLKDLMDLCDVVESKFTEKIKSM"
gene 413639..416281
/gene="DBP2"
/locus_tag="YNL112W"
/db_xref="GeneID:855611"
mRNA join(413639..414911,415914..416281)
/gene="DBP2"
/locus_tag="YNL112W"
/product="Dbp2p"
/transcript_id="NM_001182950.3"
/db_xref="GI:398364808"
/db_xref="GeneID:855611"
CDS join(413639..414911,415914..416281)
/gene="DBP2"
/locus_tag="YNL112W"
/EC_number="3.6.1.-"
/note="Essential ATP-dependent RNA helicase of the
DEAD-box protein family, involved in nonsense-mediated
mRNA decay and rRNA processing"
/codon_start=1
/product="Dbp2p"
/protein_id="NP_014287.3"
/db_xref="GI:398364809"
/db_xref="SGD:S000005056"
/db_xref="GeneID:855611"
/translation="MTYGGRDQQYNKTNYKSRGGDFRGGRNSDRNSYNDRPQGGNYRG
GFGGRSNYNQPQELIKPNWDEELPKLPTFEKNFYVEHESVRDRSDSEIAQFRKENEMT
ISGHDIPKPITTFDEAGFPDYVLNEVKAEGFDKPTGIQCQGWPMALSGRDMVGIAATG
SGKTLSYCLPGIVHINAQPLLAPGDGPIVLVLAPTRELAVQIQTECSKFGHSSRIRNT
CVYGGVPKSQQIRDLSRGSEIVIATPGRLIDMLEIGKTNLKRVTYLVLDEADRMLDMG
FEPQIRKIVDQIRPDRQTLMWSATWPKEVKQLAADYLNDPIQVQVGSLELSASHNITQ
IVEVVSDFEKRDRLNKYLETASQDNEYKTLIFASTKRMCDDITKYLREDGWPALAIHG
DKDQRERDWVLQEFRNGRSPIMVATDVAARGIDVKGINYVINYDMPGNIEDYVHRIGR
TGRAGATGTAISFFTEQNKGLGAKLISIMREANQNIPPELLKYDRRSYGGGHPRYGGG
RGGRGGYGRRGGYGGGRGGYGGNRQRDGGWGNRGRSNY"
gene complement(416940..417302)
/gene="CYB5"
/locus_tag="YNL111C"
/db_xref="GeneID:855612"
mRNA complement(416940..417302)
/gene="CYB5"
/locus_tag="YNL111C"
/product="Cyb5p"
/transcript_id="NM_001182949.3"
/db_xref="GI:398364810"
/db_xref="GeneID:855612"
CDS complement(416940..417302)
/gene="CYB5"
/locus_tag="YNL111C"
/note="Cytochrome b5, involved in the sterol and lipid
biosynthesis pathways; acts as an electron donor to
support sterol C5-6 desaturation"
/codon_start=1
/product="Cyb5p"
/protein_id="NP_014288.3"
/db_xref="GI:398364811"
/db_xref="SGD:S000005055"
/db_xref="GeneID:855612"
/translation="MPKVYSYQEVAEHNGPENFWIIIDDKVYDVSQFKDEHPGGDEII
MDLGGQDATESFVDIGHSDEALRLLKGLYIGDVDKTSERVSVEKVSTSENQSKGSGTL
VVILAILMLGVAYYLLNE"
gene complement(417826..418488)
/gene="NOP15"
/locus_tag="YNL110C"
/db_xref="GeneID:855613"
mRNA complement(417826..418488)
/gene="NOP15"
/locus_tag="YNL110C"
/product="Nop15p"
/transcript_id="NM_001182948.1"
/db_xref="GI:296147657"
/db_xref="GeneID:855613"
CDS complement(417826..418488)
/gene="NOP15"
/locus_tag="YNL110C"
/note="Constituent of 66S pre-ribosomal particles,
involved in 60S ribosomal subunit biogenesis; localizes to
both nucleolus and cytoplasm"
/codon_start=1
/product="Nop15p"
/protein_id="NP_014289.1"
/db_xref="GI:6324219"
/db_xref="SGD:S000005054"
/db_xref="GeneID:855613"
/translation="MVKSTSKTSTKETVTKQPTEEKPIQEKEELALETSSSSSDEEDE
KDEDEIEGLAASDDEQSGTHKIKRLNPKKQANEKKSKDKKTLEEYSGIIYVSRLPHGF
HEKELSKYFAQFGDLKEVRLARNKKTGNSRHYGFLEFVNKEDAMIAQESMNNYLLMGH
LLQVRVLPKGAKIEKLYKYKKRVLVEKGITKPVKQLKDNMKQKHEERIKKLAKSGIEF
KW"
gene complement(419014..419826)
/locus_tag="YNL108C"
/gene_synonym="HUF"
/db_xref="GeneID:855615"
mRNA complement(419014..419826)
/locus_tag="YNL108C"
/gene_synonym="HUF"
/product="hypothetical protein"
/transcript_id="NM_001182946.1"
/db_xref="GI:296147658"
/db_xref="GeneID:855615"
CDS complement(419014..419826)
/locus_tag="YNL108C"
/gene_synonym="HUF"
/note="hypothetical protein with similarity to Tfc7p and
prokaryotic phosphotransfer enzymes; null mutant shows
alterations in glucose metabolism; GFP-fusion protein
localizes to the cytoplasm and nucleus"
/codon_start=1
/product="hypothetical protein"
/protein_id="NP_014291.1"
/db_xref="GI:6324221"
/db_xref="SGD:S000005052"
/db_xref="GeneID:855615"
/translation="MAIENIYIARHGYRSNWLPKGPYPPPPTGIDNDVPLSEHGVEQA
HELANYISKLDVKPEMIFSSPFYRCLETSKPTVEALKIPLYVDRGVGEWYKPDRPIIP
EPATHEVMSKFFPSMISPDWEPSIIPSNKGETEEDIFERCHKFWPVFIDRVERKFPNV
KTIMIVTHAATKSALGMNLLKFSSAKEPIDNKGTFIRNGSCAIDKFELVKGENESIPF
EEREWKLTMNGNTSFLTNGEEMNWTFMNAFEAGSDADIKARRAAESGKLKME"
gene 420098..420778
/gene="YAF9"
/locus_tag="YNL107W"
/db_xref="GeneID:855616"
mRNA 420098..420778
/gene="YAF9"
/locus_tag="YNL107W"
/product="Yaf9p"
/transcript_id="NM_001182945.3"
/db_xref="GI:398364822"
/db_xref="GeneID:855616"
CDS 420098..420778
/gene="YAF9"
/locus_tag="YNL107W"
/note="Subunit of both the NuA4 histone H4
acetyltransferase complex and the SWR1 complex, may
function to antagonize silencing near telomeres; interacts
directly with Swc4p, has homology to human leukemogenic
protein AF9, contains a YEATS domain"
/codon_start=1
/product="Yaf9p"
/protein_id="NP_014292.3"
/db_xref="GI:398364823"
/db_xref="SGD:S000005051"
/db_xref="GeneID:855616"
/translation="MAPTISKRIKTLSVSRPIIYGNTAKKMGSVKPPNAPAEHTHLWT
IFVRGPQNEDISYFIKKVVFKLHDTYPNPVRSIEAPPFELTETGWGEFDINIKVYFVE
EANEKVLNFYHRLRLHPYANPVPNSDNGNEQNTTDHNSKDAEVSSVYFDEIVFNEPNE
EFFKILMSRPGNLLPSNKTDDCVYSKQLEQEEIDRIEIGIEKVDKEIDELKQKLENLV
KQEAINGS"
gene complement(420944..424495)
/gene="INP52"
/locus_tag="YNL106C"
/gene_synonym="SJL2"
/db_xref="GeneID:855618"
mRNA complement(420944..424495)
/gene="INP52"
/locus_tag="YNL106C"
/gene_synonym="SJL2"
/product="phosphatidylinositol-3-/phosphoinositide
5-phosphatase INP52"
/transcript_id="NM_001182944.1"
/db_xref="GI:296147660"
/db_xref="GeneID:855618"
CDS complement(420944..424495)
/gene="INP52"
/locus_tag="YNL106C"
/gene_synonym="SJL2"
/EC_number="3.1.3.56"
/note="Polyphosphatidylinositol phosphatase,
dephosphorylates a number of phosphatidylinositols (PIs)
to PI; involved in endocytosis; hyperosmotic stress causes
translocation to actin patches; synaptojanin-like protein
with a Sac1 domain"
/codon_start=1
/product="phosphatidylinositol-3-/phosphoinositide
5-phosphatase INP52"
/protein_id="NP_014293.1"
/db_xref="GI:6324224"
/db_xref="SGD:S000005050"
/db_xref="GeneID:855618"
/translation="MKILLSKQQTRKIAIVSETHGLVFRPINSKNSRRSTCAVELVPK
AELNGNGFRRLSNHEIYGFIGLIEIEGLMFIATITGKSKVAQPIPNKTVNKIYAVDFF
CLNNSKWDFMDIDSSGYPIVTNDGDFAISSPPSISTHSSRSSLRSSSSRSLNAQEQAP
KHPCHELRKLLSNGSFYYSTDFDLTCTLQKRGFTEHSLSFDDFDREFMWNSFLMDEII
TYRDRLDVTAKELLDQRGFLTTVIRGFAETIFSYINRLKVGLTIISRQSWKRAGTRFN
ARGIDDDGHVANFVETEMIMYSSQYCYAFTQIRGSLPIFWEQDTSLISPKIQITRSVE
ATQPTFDEHFIRLFKKYGPVHIINLLSTKSSEIQLSRRYKEQLKNSEKMKIGRDVFLT
SFDFHRETSQDGFAAASRIIPKIRNTILDAGYFSYDVKEGRLISEQDGVFRTNCLDCL
DRTNLIQQTISLAVFKLFLEDFRLVKPSSFIDDNEFVQKVNALWADNGDQISQIYTGT
NALKSSYSRKGKMSFSGALSDATKSVSRMYINNFVDKGKQQNIDTLLGKLPHQQVVEL
YDPICEYVNERLLESEEKFTTHSNINLFVGTFNVNGNSRRADLSKWLFPIGDKFKPDV
VVLGLQEVIELTAGSILNADYTKSSFWETMVTDCLNQYEEKYLLLRVEQMSSLLILFF
ARSDRAYNIKEVGGSTKKTGFGGITGNKGAVAIRFDYGATSFCFVNTHLSAGASNIDE
RRNDYNNIYRNITFPRSKTIPHHDSLFWLGDLNYRITLTNDEVRRELRAQKDGYIDRL
LQYDQLTQEINEGVVFQGFKEPTLQFRPTYKYDYGTDNYDTSEKARTPSWTDRIIYKG
ENLHPLAYSDAPLKISDHKPVYAAYRANVKFVDEKEKLNLVEKLYAEYKNTHPEALTT
GPDELSHARMEKQKESIPLDATVQSAGIKLIDLDDTSSCVSPLLSGPSPQPSVVGPGG
LSNVSPDKSKLNVLPPPPPTSRHNKEPSSKLLSPTKEISIVSVSPRKGESNLPALERH
STPKPLPPVPALSLSKPVSLQKSSSELQHAKETIDNGKIVPRPCPPIRRKSSTAPDEI
STSTKNSGVSTTEDPEPAKASTKPEKPPVVKKPHYLSVAANKLNTSQEHSIKVSPSNS
KSEEELPCKKKSKPKVPAKNPELEKLSVHPLKPCDPN"
gene complement(424895..426754)
/gene="LEU4"
/locus_tag="YNL104C"
/db_xref="GeneID:855619"
mRNA complement(424895..426754)
/gene="LEU4"
/locus_tag="YNL104C"
/product="2-isopropylmalate synthase LEU4"
/transcript_id="NM_001182942.1"
/db_xref="GI:296147661"
/db_xref="GeneID:855619"
CDS complement(424895..426754)
/gene="LEU4"
/locus_tag="YNL104C"
/EC_number="2.3.3.13"
/note="Alpha-isopropylmalate synthase (2-isopropylmalate
synthase); the main isozyme responsible for the first step
in the leucine biosynthesis pathway; LEU4 has a paralog,
LEU9, that arose from the whole genome duplication"
/codon_start=1
/product="2-isopropylmalate synthase LEU4"
/protein_id="NP_014295.1"
/db_xref="GI:6324225"
/db_xref="SGD:S000005048"
/db_xref="GeneID:855619"
/translation="MVKESIIALAEHAASRASRVIPPVKLAYKNMLKDPSSKYKPFNA
PKLSNRKWPDNRITRAPRWLSTDLRDGNQSLPDPMSVEQKKEYFHKLVNIGFKEIEVS
FPSASQTDFDFTRYAVENAPDDVSIQCLVQSREHLIKRTVEALTGAKKATIHTYLATS
DMFREIVFNMSREEAISKAVEATKLVRKLTKDDPSQQATRWSYEFSPECFSDTPGEFA
VEICEAVKKAWEPTEENPIIFNLPATVEVASPNVYADQIEYFATHITEREKVCISTHC
HNDRGCGVAATELGMLAGADRVEGCLFGNGERTGNVDLVTVAMNMYTQGVSPNLDFSD
LTSVLDVVERCNKIPVSQRAPYGGDLVVCAFSGSHQDAIKKGFNLQNKKRAQGETQWR
IPYLPLDPKDIGRDYEAVIRVNSQSGKGGAAWVILRSLGLDLPRNMQIEFSSAVQDHA
DSLGRELKSDEISKLFKEAYNYNDEQYQAISLVNYNVEKFGTERRVFTGQVKVGDQIV
DIEGTGNGPISSLVDALSNLLNVRFAVANYTEHSLGSGSSTQAASYIHLSYRRNADNE
KAYKWGVGVSEDVGDSSVRAIFATINNIIHSGDVSIPSLAEVEGKNAAASGSA"
gene 427735..429753
/gene="MET4"
/locus_tag="YNL103W"
/db_xref="GeneID:855620"
mRNA 427735..429753
/gene="MET4"
/locus_tag="YNL103W"
/product="Met4p"
/transcript_id="NM_001182941.3"
/db_xref="GI:398364832"
/db_xref="GeneID:855620"
CDS 427735..429753
/gene="MET4"
/locus_tag="YNL103W"
/note="Leucine-zipper transcriptional activator,
responsible for the regulation of the sulfur amino acid
pathway, requires different combinations of the auxiliary
factors Cbf1p, Met28p, Met31p and Met32p"
/codon_start=1
/product="Met4p"
/protein_id="NP_014296.4"
/db_xref="GI:398364833"
/db_xref="SGD:S000005047"
/db_xref="GeneID:855620"
/translation="MKQEQSHEGDSYSTEFINLFGKDTATHPSSNNGANNNGMGSTNS
LDQFVATASSSSSLVTSSENRRPLIGDVTNRGNTNLYDHAVTPEILLEQLAYVDNFIP
SLDNEFSNVDWNVNTTHNNANNNGADTFSSINANPFDLDEQLAIELSAFADDSFIFPD
EDKPSNNNNNSNNGNDDHSNHDVLHEDPSTNNRQRNPHFLTQRRNTFLTSQYDQSKSR
FSSKNKRNGNNGETNNFGDNMQNNHPFEPNFMGSPSQFPADATNMTSIDHGGFTNVDI
TSTENNTTGDNGVDALSNLLHRTTHTPNRSSPLSNVTSAQNSSSQQRKHSESKVDSNS
DNNSSNKAPNITVPDYSIIPTSVLVTLLPRVNVPNGAYNSLISAGFDNDQIDAIAAIM
AYHHQKKIRENNSNNNKNINTNDSQEAPILKNINELLSVLIPPSPAETAAPTTLSTSP
SFNEHGVVAEASFLSSILELGIKHPKSNNIHNQRQPSRNDHKISRESDGNNGNDNVHH
NNAVIKSSTTRGDEIAKIRSEPTLNASSSDHKENSLKRSHSGDLKNKKVPVDRKYSDN
EDDEYDDADLHGFEKKQLIKKELGDDDEDLLIQSKKSHQKKKLKEKELESSIHELTEI
AASLQKRIHTLETENKLLKNLVLSSGETEGIKKAESLKKQIFEKVQKE"
gene 430087..434493
/gene="POL1"
/locus_tag="YNL102W"
/gene_synonym="CDC17; CRT5; HPR3"
/db_xref="GeneID:855621"
mRNA 430087..434493
/gene="POL1"
/locus_tag="YNL102W"
/gene_synonym="CDC17; CRT5; HPR3"
/product="Pol1p"
/transcript_id="NM_001182940.3"
/db_xref="GI:398364842"
/db_xref="GeneID:855621"
CDS 430087..434493
/gene="POL1"
/locus_tag="YNL102W"
/gene_synonym="CDC17; CRT5; HPR3"
/EC_number="2.7.7.7"
/note="Catalytic subunit of the DNA polymerase I
alpha-primase complex, required for the initiation of DNA
replication during mitotic DNA synthesis and premeiotic
DNA synthesis"
/codon_start=1
/product="Pol1p"
/protein_id="NP_014297.3"
/db_xref="GI:398364843"
/db_xref="SGD:S000005046"
/db_xref="GeneID:855621"
/translation="MSSKSEKLEKLRKLQAARNGTSIDDYEGDESDGDRIYDEIDEKE
YRARKRQELLHDDFVVDDDGVGYVDRGVEEDWREVDNSSSDEDTGNLASKDSKRKKNI
KREKDHQITDMLRTQHSKSTLLAHAKKSQKKSIPIDNFDDILGEFESGEVEKPNILLP
SKLRENLNSSPTSEFKSSIKRVNGNDESSHDAGISKKVKIDPDSSTDKYLEIESSPLK
LQSRKLRYANDVQDLLDDVENSPVVATKRQNVLQDTLLANPPSAQSLADEEDDEDSDE
DIILKRRTMRSVTTTRRVNIDSRSNPSTSPFVTAPGTPIGIKGLTPSKSLQSNTDVAT
LAVNVKKEDVVDPETDTFQMFWLDYCEVNNTLILFGKVKLKDDNCVSAMVQINGLCRE
LFFLPREGKTPTDIHEEIIPLLMDKYGLDNIRAKPQKMKYSFELPDIPSESDYLKVLL
PYQTPKSSRDTIPSDLSSDTFYHVFGGNSNIFESFVIQNRIMGPCWLDIKGADFNSIR
NASHCAVEVSVDKPQNITPTTTKTMPNLRCLSLSIQTLMNPKENKQEIVSITLSAYRN
ISLDSPIPENIKPDDLCTLVRPPQSTSFPLGLAALAKQKLPGRVRLFNNEKAMLSCFC
AMLKVEDPDVIIGHRLQNVYLDVLAHRMHDLNIPTFSSIGRRLRRTWPEKFGRGNSNM
NHFFISDICSGRLICDIANEMGQSLTPKCQSWDLSEMYQVTCEKEHKPLDIDYQNPQY
QNDVNSMTMALQENITNCMISAEVSYRIQLLTLTKQLTNLAGNAWAQTLGGTRAGRNE
YILLHEFSRNGFIVPDKEGNRSRAQKQRQNEENADAPVNSKKAKYQGGLVFEPEKGLH
KNYVLVMDFNSLYPSIIQEFNICFTTVDRNKEDIDELPSVPPSEVDQGVLPRLLANLV
DRRREVKKVMKTETDPHKRVQCDIRQQALKLTANSMYGCLGYVNSRFYAKPLAMLVTN
KGREILMNTRQLAESMNLLVVYGDTDSVMIDTGCDNYADAIKIGLGFKRLVNERYRLL
EIDIDNVFKKLLLHAKKKYAALTVNLDKNGNGTTVLEVKGLDMKRREFCPLSRDVSIH
VLNTILSDKDPEEALQEVYDYLEDIRIKVETNNIRIDKYKINMKLSKDPKAYPGGKNM
PAVQVALRMRKAGRVVKAGSVITFVITKQDEIDNAADTPALSVAERAHALNEVMIKSN
NLIPDPQYYLEKQIFAPVERLLERIDSFNVVRLSEALGLDSKKYFRREGGNNNGEDIN
NLQPLETTITDVERFKDTVTLELSCPSCDKRFPFGGIVSSNYYRVSYNGLQCKHCEQL
FTPLQLTSQIEHSIRAHISLYYAGWLQCDDSTCGIVTRQVSVFGKRCLNDGCTGVMRY
KYSDKQLYNQLLYFDSLFDCEKNKKQELKPIYLPDDLDYPKEQLTESSIKALTEQNRE
LMETGRSVVQKYLNDCGRRYVDMTSIFDFMLN"
gene 434999..437140
/gene="AVT4"
/locus_tag="YNL101W"
/db_xref="GeneID:855622"
mRNA 434999..437140
/gene="AVT4"
/locus_tag="YNL101W"
/product="Avt4p"
/transcript_id="NM_001182939.1"
/db_xref="GI:296147664"
/db_xref="GeneID:855622"
CDS 434999..437140
/gene="AVT4"
/locus_tag="YNL101W"
/note="Vacuolar transporter, exports large neutral amino
acids from the vacuole; member of a family of seven S.
cerevisiae genes (AVT1-7) related to vesicular
GABA-glycine transporters"
/codon_start=1
/product="Avt4p"
/protein_id="NP_014298.1"
/db_xref="GI:6324228"
/db_xref="SGD:S000005045"
/db_xref="GeneID:855622"
/translation="MVTNNGDGEHLGIRRNGNLRHPSNNMKIPRRAQSTVLNSNPFYS
RKYSMSTLTPRDICRSVDSRVFVDMSSPNFQTLEDPHRDEIINSVRLNYLNSSKRSSV
SHGNEAIPRVNPTKNSSASTIAAANVDSDDDETNLSSAGGDITHDIYKLVKAEDPKRL
RRPRSMENVTPKIEHHTKLSSASGLNVPGGFRREFIVNKKRQEHQLNDSASSDFTSHE
SDSINQSSPSSNQDIDKVPFLTRNFLEFLYVFGHFAGESFEDDFIPDSSNMMIRGEDE
RSALLSRPDHMKVLPSAKGTTSTKKVFLILLKSFIGTGVLFLPNAFHNGGLFFSVSML
AFFGIYSYWCYYILVQAKSSCGVSSFGDIGLKLYGPWMRIIILFSLVITQVGFSGAYM
IFTAKNLQAFLDNVFHVGVLPLSYLMVFQTIIFIPLSFIRNISKLSLPSLLANFFIMA
GLVIVIIFTAKRLFFDLMGTPAMGVVYGLNADRWTLFIGTAIFAFEGIGLIIPVQDSM
RNPEKFPLVLALVILTATILFISIATLGYLAYGSNVQTVILLNLPQSNIFVNLIQLFY
SIAIMLSTPLQLFPAIKIIENKFFPKFTKIYVKHDDLTTRVELRPNSGKLNWKIKWLK
NFIRSIIVIIVVSIAYFGSDNLDKFVSVIGSLACIPLVYIYPSMLHLRGNSLPETKGE
FWRFKPMLDTILIFFGIASMLYTSYQSIFGV"
gene 437613..438317
/gene="AIM37"
/locus_tag="YNL100W"
/gene_synonym="MCS27"
/db_xref="GeneID:855623"
mRNA 437613..438317
/gene="AIM37"
/locus_tag="YNL100W"
/gene_synonym="MCS27"
/product="Aim37p"
/transcript_id="NM_001182938.1"
/db_xref="GI:296147665"
/db_xref="GeneID:855623"
CDS 437613..438317
/gene="AIM37"
/locus_tag="YNL100W"
/gene_synonym="MCS27"
/note="Mitochondrial inner membrane protein; component of
the mitochondrial inner membrane organizing system (MitOS,
MICOS, or MINOS), a scaffold-like structure on the
intermembrane space side of the inner membrane which has a
role in the maintenance of crista junctions and inner
membrane architecture"
/codon_start=1
/product="Aim37p"
/protein_id="NP_014299.1"
/db_xref="GI:6324229"
/db_xref="SGD:S000005044"
/db_xref="GeneID:855623"
/translation="MVNFYDDVDESKSHGEFPLIPVVLQNSSELSVRTIPTGNEIIES
VHLTKWLRKYRNALASQLDRYEKGWQSKIANFRLQVQHVINYSRKNIFNVDSENKHTV
VPGSLIALGAFFAGSIAVNRSNWGAKRLIFGHKSSILEKLCTSLPSRILLPWVLAAAT
FKYWAPQTSQNLVNATENDLLPADFVKSYHNTWKRIYEEGYVAKKCDLKRQIDQTLQK
NIRYAREQLYEKLEQA"
gene complement(438567..439283)
/gene="OCA1"
/locus_tag="YNL099C"
/db_xref="GeneID:855624"
mRNA complement(438567..439283)
/gene="OCA1"
/locus_tag="YNL099C"
/product="Oca1p"
/transcript_id="NM_001182937.3"
/db_xref="GI:398364852"
/db_xref="GeneID:855624"
CDS complement(438567..439283)
/gene="OCA1"
/locus_tag="YNL099C"
/note="Putative protein tyrosine phosphatase, required for
cell cycle arrest in response to oxidative damage of DNA"
/codon_start=1
/product="Oca1p"
/protein_id="NP_014300.3"
/db_xref="GI:398364853"
/db_xref="SGD:S000005043"
/db_xref="GeneID:855624"
/translation="MTSKVGEYEDVPEDESRLTEENVSVPEEEVEDEDEEEDDDDDHI
YINEETESGREKVLVSHAPQERIVPPLNFCPVERYLYRSGQPSPVNFPFLLNLKLKTI
IWLSNEEPQDTLLEFCDTHRINLQFAAINPDAGEDDNPWDGLTEHSIINVLQTIVTQE
NYPLLVCCGMGRHRTGTVIGCLRRIMGWNLASVSEEYRRFTGSRGGRILVELLIEAFD
TNLVKIDKNKAPSWLLTALE"
gene complement(439602..440570)
/gene="RAS2"
/locus_tag="YNL098C"
/gene_synonym="CTN5; CYR3; GLC5; TSL7"
/db_xref="GeneID:855625"
mRNA complement(439602..440570)
/gene="RAS2"
/locus_tag="YNL098C"
/gene_synonym="CTN5; CYR3; GLC5; TSL7"
/product="Ras2p"
/transcript_id="NM_001182936.1"
/db_xref="GI:296147667"
/db_xref="GeneID:855625"
CDS complement(439602..440570)
/gene="RAS2"
/locus_tag="YNL098C"
/gene_synonym="CTN5; CYR3; GLC5; TSL7"
/note="GTP-binding protein that regulates the nitrogen
starvation response, sporulation, and filamentous growth;
farnesylation and palmitoylation required for activity and
localization to plasma membrane; homolog of mammalian Ras
proto-oncogenes"
/codon_start=1
/product="Ras2p"
/protein_id="NP_014301.1"
/db_xref="GI:6324231"
/db_xref="SGD:S000005042"
/db_xref="GeneID:855625"
/translation="MPLNKSNIREYKLVVVGGGGVGKSALTIQLTQSHFVDEYDPTIE
DSYRKQVVIDDEVSILDILDTAGQEEYSAMREQYMRNGEGFLLVYSITSKSSLDELMT
YYQQILRVKDTDYVPIVVVGNKSDLENEKQVSYQDGLNMAKQMNAPFLETSAKQAINV
EEAFYTLARLVRDEGGKYNKTLTENDNSKQTSQDTKGSGANSVPRNSGGHRKMSNAAN
GKNVNSSTTVVNARNASIESKTGLAGNQATNGKTQTDRTNIDNSTGQAGQANAQSANT
VNNRVNNNSKAGQVSNAKQARKQQAAPGGNTSEASKSGSGGCCIIS"
gene complement(440797..440919)
/locus_tag="YNL097C-B"
/gene_synonym="YNL097C-A"
/db_xref="GeneID:1466513"
mRNA complement(440797..440919)
/locus_tag="YNL097C-B"
/gene_synonym="YNL097C-A"
/product="hypothetical protein"
/transcript_id="NM_001184620.1"
/db_xref="GI:296147668"
/db_xref="GeneID:1466513"
CDS complement(440797..440919)
/locus_tag="YNL097C-B"
/gene_synonym="YNL097C-A"
/codon_start=1
/product="hypothetical protein"
/protein_id="NP_878155.1"
/db_xref="GI:33438867"
/db_xref="SGD:S000028699"
/db_xref="GeneID:1466513"
/translation="MTAKTKQSWNKGIWENGKQGSHQQTFLPKIWVNIYSTPTS"
gene complement(441366..442358)
/gene="PHO23"
/locus_tag="YNL097C"
/db_xref="GeneID:855626"
mRNA complement(441366..442358)
/gene="PHO23"
/locus_tag="YNL097C"
/product="Pho23p"
/transcript_id="NM_001182935.3"
/db_xref="GI:398364870"
/db_xref="GeneID:855626"
CDS complement(441366..442358)
/gene="PHO23"
/locus_tag="YNL097C"
/note="Probable component of the Rpd3 histone deacetylase
complex, involved in transcriptional regulation of PHO5;
affects termination of snoRNAs and cryptic unstable
transcripts (CUTs); C-terminus has similarity to human
candidate tumor suppressor p33(ING1) and its isoform ING3"
/codon_start=1
/product="Pho23p"
/protein_id="NP_014302.3"
/db_xref="GI:398364871"
/db_xref="SGD:S000005041"
/db_xref="GeneID:855626"
/translation="MSSPANLFPGLNDITDVLEEFPLATSRYLTLLHEIDAKCVHSMP
NLNERIDKFLKKDFNKDHQTQVRLLNNINKIYEELMPSLEEKMHVSSIMLDNLDRLTS
RLELAYEVAIKNTEIPRGLRLGVDNHPAMHLHHELMEKIESKSNSKSSQALKSESRRE
AMAANRRQGEHYSASTHQQDDSKNDANYGGSRHESQDHTGNNTNSRKRANAANTNNAD
PETKKRKRRVATTAVSPSTISTATAVNNGRIGTSTASRGVSSVGNSNNSRISRPKTND
YGEPLYCYCNQVAYGEMVGCDGADCELEWFHLPCIGLETLPKGKWYCDDCKKKL"
gene 443006..443119
/locus_tag="tL(CAA)N"
/db_xref="GeneID:855627"
tRNA join(443006..443043,443076..443119)
/locus_tag="tL(CAA)N"
/product="tRNA-Leu"
/note="Leucine tRNA (tRNA-Leu), predicted by tRNAscan-SE
analysis"
/db_xref="SGD:S000006645"
/db_xref="GeneID:855627"
gene complement(443398..444315)
/gene="RPS7B"
/locus_tag="YNL096C"
/db_xref="GeneID:855628"
mRNA complement(join(443398..443826,444172..444315))
/gene="RPS7B"
/locus_tag="YNL096C"
/product="ribosomal 40S subunit protein S7B"
/transcript_id="NM_001182934.3"
/db_xref="GI:398364882"
/db_xref="GeneID:855628"
CDS complement(join(443398..443826,444172..444315))
/gene="RPS7B"
/locus_tag="YNL096C"
/note="Protein component of the small (40S) ribosomal
subunit; interacts with Kti11p; deletion causes
hypersensitivity to zymocin; homologous to mammalian
ribosomal protein S7, no bacterial homolog; RPS7B has a
paralog, RPS7A, that arose from the whole genome
duplication; protein abundance increases in response to
DNA replication stress"
/codon_start=1
/product="ribosomal 40S subunit protein S7B"
/protein_id="NP_014303.3"
/db_xref="GI:398364883"
/db_xref="SGD:S000005040"
/db_xref="GeneID:855628"
/translation="MSSVQSKILSQAPSELELQVAKTFIDLESSSPELKADLRPLQIK
SIREIDVTGGKKALVLFVPVPALSAYHKVQTKLTRELEKKFPDRHVIFLAERRILPKP
SRTSRQVQKRPRSRTLTAVHDKVLEDMVFPTEIVGKRVRYLVGGNKIQKVLLDSKDVQ
QIDYKLESFQAVYNKLTGKQIVFEIPSQTN"
gene complement(444912..446840)
/locus_tag="YNL095C"
/db_xref="GeneID:855629"
mRNA complement(444912..446840)
/locus_tag="YNL095C"
/product="hypothetical protein"
/transcript_id="NM_001182933.1"
/db_xref="GI:296147671"
/db_xref="GeneID:855629"
CDS complement(444912..446840)
/locus_tag="YNL095C"
/note="hypothetical protein predicted to contain a
transmembrane domain; YNL095C is not an essential gene"
/codon_start=1
/product="hypothetical protein"
/protein_id="NP_014304.1"
/db_xref="GI:6324234"
/db_xref="SGD:S000005039"
/db_xref="GeneID:855629"
/translation="MVHITLGQAIWVSVKPIIKIYLIIGVGFLMAKMGILTVEATRII
SDIVLTVLLPSLSFNKIVANIEDKDIKSVGIICLSALLIFGSGFFFAYVVRLFLPVPK
QWYGGILAGGMFPNISDLPIAYLQSMDQGLVFSEEEGNKGVANVIIFLTMFLICIFNL
GGFRLIESDFEYNDDESAVRVSETTKTQPAVSANTTNTDTSERFFSNEQQLFNNKYTA
RDSLTEAIGTKGENADVPPISRRSTNSIAPLSLPDTSSNSKITKPVQVKARNTIACTQ
SEESQATRGSNPLDSQSSASTIHSYNTSESYESSIDTMRARRTASQPRAYNTTTLLEE
NCLDEKCPKNMSMAALEPIRSIDMRALPSQNIHHLIREYSNVDQYGHQRRNSSLRGAD
MNDVHSISSNSTLQTIKTANLTRILTSDATVSKKDIETSGESLPQWMRKFSLTPLLVF
FLKNCLRPCSMAVIIALTVAFIPWVKALFVTTANTPHISQAPDNAPPLSFFMDFTGYV
GAACVPFGLILLGATLGRLKIGNLYPGFWKAAVTLVILRQCVMPIFGVLWCDRLVKAG
WVNWQDDRMLLFVIAISWNLPTMTTLIYFTASFTPPETTAPIQMECVSFFLMLQYPLM
VVSLPFLVSYFLKVQMNL"
gene 447611..449374
/gene="APP1"
/locus_tag="YNL094W"
/db_xref="GeneID:855630"
mRNA 447611..449374
/gene="APP1"
/locus_tag="YNL094W"
/product="phosphatidate phosphatase APP1"
/transcript_id="NM_001182932.1"
/db_xref="GI:296147672"
/db_xref="GeneID:855630"
CDS 447611..449374
/gene="APP1"
/locus_tag="YNL094W"
/note="Phosphatidate phosphatase, converts phosphatidate
to diacylglycerol; App1p, Pah1p, Dpp1p, and Lpp1p are
responsible for all the phosphatidate phosphatase
activity; component of cortical actin patches; interacts
with components of endocytic pathway"
/codon_start=1
/product="phosphatidate phosphatase APP1"
/protein_id="NP_014305.1"
/db_xref="GI:6324235"
/db_xref="SGD:S000005038"
/db_xref="GeneID:855630"
/translation="MNSQGYDESSSSTAATSGPTSGDPRMGKKQRFMNLIRTTKDVYI
PNLTSSISQKTMDGIRSTTNSFEGYNDLPMELPHNTTITYFPTYTTTNLVDPDGLSAP
RKDFETTVRCAVSYPGNPTSRRNRWLLSLCKQYLRTGTAEADVAPVVPPHLEEDSGDL
NDSQSSIESSLSSKSENRYSHMGIQEEDVLNERIQGFLSKKVPNTPVVVDLLPKDKLR
GDTASFFGTTDSYGNLLIKAETDFLPSKINITLDTPIEGHADPISETFPANYVSPYGI
GLISDIDDTIKHTGVTGDRRSMFRNVFIHDVQSWVIDGVPLWYKTLHDVADVDFFYVS
NSPIQTFTLLKQYICANFPPGPIFLKQYSGNFFSTIMTSSANRKIQPIANILKDFPKK
KFILVGDSGEHDLEAYTTTALQFPNQILAIYIRCCSNSMSDVPSHDEEVMNEVNNIIE
LQQRPMQMTKSTVRTRRRPPPPPIPSTQKPSLTEEQTESIRMSRRNKDENNAKRVAPP
PLPNRQLPNLDANTYYVPSSQNDYGMYGAFMDKKADEWKRRVMDSIQKLSNQDTTLMF
FSDPALSLEDSIRRIREKYSN"
rep_origin 449347..449591
/note="ARS1419;
Autonomously Replicating Sequence"
/db_xref="SGD:S000118387"
gene 449868..450530
/gene="YPT53"
/locus_tag="YNL093W"
/db_xref="GeneID:855631"
mRNA 449868..450530
/gene="YPT53"
/locus_tag="YNL093W"
/product="Ypt53p"
/transcript_id="NM_001182931.3"
/db_xref="GI:398364898"
/db_xref="GeneID:855631"
CDS 449868..450530
/gene="YPT53"
/locus_tag="YNL093W"
/note="Rab family GTPase, similar to Ypt51p and Ypt52p and
to mammalian rab5; required for vacuolar protein sorting
and endocytosis"
/codon_start=1
/product="Ypt53p"
/protein_id="NP_014306.3"
/db_xref="GI:398364899"
/db_xref="SGD:S000005037"
/db_xref="GeneID:855631"
/translation="MDKHTAAIPTLTIKVVLLGESAVGKSSIVLRFVSDDFKESKEPT
IGAAFLTKRITRDGKVIKFEIWDTAGQERFAPLAPMYYRNAQAALVVFDVTNEGSFYK
AQNWVEELHEKVGHDIVIALVGNKMDLLNNDDENENRAMKAPAVQNLCERENLLYFEA
SAKTGENIYQIFQTLGEKVPCPEQNTRQSSTHDRTITDNQRIDLESTTVESTRETGGC
NC"
gene 450871..452073
/locus_tag="YNL092W"
/db_xref="GeneID:855632"
mRNA 450871..452073
/locus_tag="YNL092W"
/product="hypothetical protein"
/transcript_id="NM_001182930.1"
/db_xref="GI:296147674"
/db_xref="GeneID:855632"
CDS 450871..452073
/locus_tag="YNL092W"
/note="Putative S-adenosylmethionine-dependent
methyltransferase of the seven beta-strand family; YNL092W
is not an essential gene"
/codon_start=1
/product="hypothetical protein"
/protein_id="NP_014307.1"
/db_xref="GI:6324237"
/db_xref="SGD:S000005036"
/db_xref="GeneID:855632"
/translation="MDENEFDNQRENKAVARVIISFLKYEEYALKEIYNLRVKKWASI
SDRQKDMVPNYTKYLANLKAAIIENGKFFRSVAEYALQSISFEPGEIVQPNDLDMSKT
CSLLTQVYREWSAEAISERNCLNSRLVPFLKTLSPPKADILIPGCGTGRLLVDLSRMG
YNCEGNEFSYHMLLVSQYMLNAGLLQNQIIIYPFIHCFSHWKKIEDQLSPIKVPDIEA
WSSNKGMGSMSICAGSFVDCYGRNQGTKISSHYTFSRRMQLSRAKAENSKDVVVTNFF
IDTGSNILDYLDTIGHVLKPGGIWCNFGPLLYHFENDHGVETTYEVNPYSGFQDKIND
YTPLMGLELSSDDIISIATNHLDFELIRRESGILCGYGRYAGPESCAMPGYMCHYWIL
KSNPTNES"
gene 452408..456130
/gene="NST1"
/locus_tag="YNL091W"
/db_xref="GeneID:855633"
mRNA 452408..456130
/gene="NST1"
/locus_tag="YNL091W"
/product="Nst1p"
/transcript_id="NM_001182929.1"
/db_xref="GI:296147675"
/db_xref="GeneID:855633"
CDS 452408..456130
/gene="NST1"
/locus_tag="YNL091W"
/note="hypothetical protein, mediates sensitivity to salt
stress; interacts physically with the splicing factor
Msl1p and also displays genetic interaction with MSL1"
/codon_start=1
/product="Nst1p"
/protein_id="NP_014308.1"
/db_xref="GI:6324238"
/db_xref="SGD:S000005035"
/db_xref="GeneID:855633"
/translation="MPPNSKSKRRKNKSKQHNKKNGNSDPEQSINPTQLVPRMEPELY
HTESDYPTSRVIKRAPNGDVIVEPINTDDDKKERTANLTHNKDSMDSASSLAFTLDSH
WESLSPEEKKTILRIEKEEVFNVIRNYQDDHSCSCSVCGRRHLAMDQEMERIYNTLYA
MDKDKDPETNPIKFHLGIIKELQISKNQQQNDLSSTKGEVVKNFLSSSTVGSLKEEVL
HFKQKQLSKQEQAHNETADNTSLLEENLNNIHINKTSSEISANFNSVSDEELQQKYSN
FTKTFISSHPKIAEEYVQKMMMYPNIRALTDDLMNSNGQGFLNAIEDFVRDGQIQASK
KDDSITEDEASSTDLTDPKEFTTMLHSGKPLTEDEYADLQRNIAERMTNAYDTASKKF
KDVSQLEKELFTRFMSGRDKKSFRELIIQSFKNKFDGELGPSVLAATLSSCFSSQSKD
TSLDTDSIYEDEDEEDYDDYSEYAEDSEEVSEYEGIEAVEKPEHDEKSNGIRETLHLS
YDHDHKRQNHPHHHYHSTSTHSEDELSEEEYISDIELPHDPHKHFHRDDDILDGDEDE
PEEEDENEGDDEEDTYDSGLDETDRLEEGRKLIQIAITKLLQSRIMASYHEKQADNNR
LKLLQELEEEKRKKREKEEKKQKKREKEKEKKRLQQLAKEEEKRKREEEKERLKKELE
EREMRRREAQRKKVEEAKRKKDEERKRRLEEQQRREEMQEKQRKQKEELKRKREEEKK
RIREQKRLEQEKLQKEKEEEERQRLIAEDALRKQKLNEEQTSANILSAKPFTENGVGN
PVSSQSHPNMTNYQEDNSCSINDEILKMVNSVAASKPVSPTGFNVHDLLLPSTNNQMP
AMEQSHLPQPGNQNNHFGTTTIPNALDLATKSSLQTENNYLMNSQTLENTSLLMHNNS
SPTKLLPNDFGLSSWGGLTNTMSINPTCKPPVIQTSEMESQAHKSSPQATMPSFGLPN
GGTHRKSFTDELNTLTSMLSSSGFADTSLSSSGFPPSQRSVWNDQKSSFSGPSTAGNF
NNSSIQSGMLLAPTLGSVESFPNRTSIWDSSTTPMMNKSELSGRNITSTAQDSPAFMA
SNIWSSNSQYNSPYLTSNVLQSPQISSGVDESHILDSIYNTYLAISPQDSLNPYIAIG
TLFQNLVGLNLDYSTFINKLISMQGAYNCEFFTDNNGSITHVRFARQTPAGHSKGLLN
QLFSGLNDPTATPFTSRPHTSTRASFPIASSTTQTS"
gene 456565..457143
/gene="RHO2"
/locus_tag="YNL090W"
/db_xref="GeneID:855634"
mRNA 456565..457143
/gene="RHO2"
/locus_tag="YNL090W"
/product="Rho2p"
/transcript_id="NM_001182928.3"
/db_xref="GI:398364926"
/db_xref="GeneID:855634"
CDS 456565..457143
/gene="RHO2"
/locus_tag="YNL090W"
/note="Non-essential small GTPase of the Rho/Rac subfamily
of Ras-like proteins, involved in the establishment of
cell polarity and in microtubule assembly"
/codon_start=1
/product="Rho2p"
/protein_id="NP_014309.3"
/db_xref="GI:398364927"
/db_xref="SGD:S000005034"
/db_xref="GeneID:855634"
/translation="MSEKAVRRKLVIIGDGACGKTSLLYVFTLGKFPEQYHPTVFENY
VTDCRVDGIKVSLTLWDTAGQEEYERLRPFSYSKADIILIGFAVDNFESLINARTKWA
DEALRYCPDAPIVLVGLKKDLRQEAHFKENATDEMVPIEDAKQVARAIGAKKYMECSA
LTGEGVDDVFEVATRTSLLMKKEPGANCCIIL"
gene 457704..461990
/gene="TOP2"
/locus_tag="YNL088W"
/gene_synonym="TOR3; TRF3"
/db_xref="GeneID:855636"
mRNA 457704..461990
/gene="TOP2"
/locus_tag="YNL088W"
/gene_synonym="TOR3; TRF3"
/product="DNA topoisomerase 2"
/transcript_id="NM_001182926.3"
/db_xref="GI:398364936"
/db_xref="GeneID:855636"
CDS 457704..461990
/gene="TOP2"
/locus_tag="YNL088W"
/gene_synonym="TOR3; TRF3"
/EC_number="5.99.1.3"
/note="Topoisomerase II, relieves torsional strain in DNA
by cleaving and re-sealing the phosphodiester backbone of
both positively and negatively supercoiled DNA; cleaves
complementary strands; localizes to axial cores in
meiosis; required for replication slow zone (RSZ) breakage
following Mec1p inactivation"
/codon_start=1
/product="DNA topoisomerase 2"
/protein_id="NP_014311.3"
/db_xref="GI:398364937"
/db_xref="SGD:S000005032"
/db_xref="GeneID:855636"
/translation="MSTEPVSASDKYQKISQLEHILKRPDTYIGSVETQEQLQWIYDE
ETDCMIEKNVTIVPGLFKIFDEILVNAADNKVRDPSMKRIDVNIHAEEHTIEVKNDGK
GIPIEIHNKENIYIPEMIFGHLLTSSNYDDDEKKVTGGRNGYGAKLCNIFSTEFILET
ADLNVGQKYVQKWENNMSICHPPKITSYKKGPSYTKVTFKPDLTRFGMKELDNDILGV
MRRRVYDINGSVRDINVYLNGKSLKIRNFKNYVELYLKSLEKKRQLDNGEDGAAKSDI
PTILYERINNRWEVAFAVSDISFQQISFVNSIATTMGGTHVNYITDQIVKKISEILKK
KKKKSVKSFQIKNNMFIFINCLIENPAFTSQTKEQLTTRVKDFGSRCEIPLEYINKIM
KTDLATRMFEIADANEENALKKSDGTRKSRITNYPKLEDANKAGTKEGYKCTLVLTEG
DSALSLAVAGLAVVGRDYYGCYPLRGKMLNVREASADQILKNAEIQAIKKIMGLQHRK
KYEDTKSLRYGHLMIMTDQDHDGSHIKGLIINFLESSFPGLLDIQGFLLEFITPIIKV
SITKPTKNTIAFYNMPDYEKWREEESHKFTWKQKYYKGLGTSLAQEVREYFSNLDRHL
KIFHSLQGNDKDYIDLAFSKKKADDRKEWLRQYEPGTVLDPTLKEIPISDFINKELIL
FSLADNIRSIPNVLDGFKPGQRKVLYGCFKKNLKSELKVAQLAPYVSECTAYHHGEQS
LAQTIIGLAQNFVGSNNIYLLLPNGAFGTRATGGKDAAAARYIYTELNKLTRKIFHPA
DDPLYKYIQEDEKTVEPEWYLPILPMILVNGAEGIGTGWSTYIPPFNPLEIIKNIRHL
MNDEELEQMHPWFRGWTGTIEEIEPLRYRMYGRIEQIGDNVLEITELPARTWTSTIKE
YLLLGLSGNDKIKPWIKDMEEQHDDNIKFIITLSPEEMAKTRKIGFYERFKLISPISL
MNMVAFDPHGKIKKYNSVNEILSEFYYVRLEYYQKRKDHMSERLQWEVEKYSFQVKFI
KMIIEKELTVTNKPRNAIIQELENLGFPRFNKEGKPYYGSPNDEIAEQINDVKGATSD
EEDEESSHEDTENVINGPEELYGTYEYLLGMRIWSLTKERYQKLLKQKQEKETELENL
LKLSAKDIWNTDLKAFEVGYQEFLQRDAEARGGNVPNKGSKTKGKGKRKLVDDEDYDP
SKKNKKSTARKGKKIKLEDKNFERILLEQKLVTKSKAPTKIKKEKTPSVSETKTEEEE
NAPSSTSSSSIFDIKKEDKDEGELSKISNKFKKISTIFDKMGSTSATSKENTPEQDDV
ATKKNQTTAKKTAVKPKLAKKPVRKQQKVVELSGESDLEILDSYTDREDSNKDEDDAI
PQRSRRQRSSRAASVPKKSYVETLELSDDSFIEDDEEENQGSDVSFNEED"
gene 462411..465947
/gene="TCB2"
/locus_tag="YNL087W"
/db_xref="GeneID:855637"
mRNA 462411..465947
/gene="TCB2"
/locus_tag="YNL087W"
/product="Tcb2p"
/transcript_id="NM_001182925.1"
/db_xref="GI:296147678"
/db_xref="GeneID:855637"
CDS 462411..465947
/gene="TCB2"
/locus_tag="YNL087W"
/note="Bud-specific protein with a potential role in
membrane trafficking; localizes to endoplasmic reticulum
and is enriched at ER-plasma membrane contact sites;
GFP-fusion protein migrates from the cell surface to
intracellular vesicles near vacuole; contains 3 calcium
and lipid binding domains; mRNA is targeted to the bud"
/codon_start=1
/product="Tcb2p"
/protein_id="NP_014312.1"
/db_xref="GI:6324242"
/db_xref="SGD:S000005031"
/db_xref="GeneID:855637"
/translation="MSPNSSKTRTDQISSMPGINEATKVESKNVVKDAVPIKSEVETN
GTSIVREKQDPSYVGWKQVGGWEEKDELTSEDLLVDVNKDTFLGNLLPDKFYGDWYHE
VAILIIAGLCSFVLGYFKFSLASVLIVMLTTGMLYRTSSKKYRESLRDLAQKEQTVEK
ITSDYESVEWLNTFLDKYWPIIEPSVSQQIVDGTNTALSENVAIPKFIKAIWLDQFTL
GVKPPRIDAIKTFQNTKSDVVVMDVCLSFTPHDMSDLDAKQCRNYVNSNVVLKAKIFG
MDIPVSVADIFFQVFVRFRFQLMTTLPLVETINIQLLEVPEVDFISRLLGNSVFNWEI
LAIPGLMRLIQKMAFKYLSPVLLPPFSLQLNIPQLLSKTGLPIGVLEIKVKNAHGLRK
LVGMIKKTVDPYLTFELSGKIVGKTKVFKNSANPVWNESIYILLQSFTDPLTIAVYDK
RETLSDKKMGTVIFNLNKLHANHYHKNEKVHFLRNSKPVGELTFDLRFFPTIEPKKLL
NGDEEPLPDMNTGITKITIRELKGLDELSDKKFVFAELYVNAELVMTTKKEKRTAHLK
WNSDYYSVVTDRRKTICRFVLKDQSGKVISSSVQPLNHLIDRTEVNKEWIPLRNGKGE
LKVTTYWRPVDIDLGLKSVGYTTPIGMLRVFINKAENLRNPDSLGKISPYAKVSVNGV
ARGRTNERIETLNPIWNQSIYVSVTSPLQKVSIDCFGIDTNGDDHNLGSLNIQTQNIY
HKDNDDKYTIFIDNAPRTGNLIGKKGVKGTVTYYLSFYPVVPVLSLEEAKEVDEINEK
KDKLEKQKSTLDDKNISKEEKERIKKEEFRLTEKYDMYSYKMKLDLDELLQYNAGVLG
VTVLGGELPQPGLYVQTFFDSCGYAAITSAKNAIRTIKTGWSGDFMIKELEWSVTTFR
VTKTKDANKAENFICEVNIPTIELVRNCYYKPSVLNLIGKKSAKLLVQVSWFPVTATE
LPQSDLITNSGDLKITAKSAENLIGVNKNGYSDPYVEFFLNEKSTSPFFKTAVQKKTL
NPTWNESKTIEVSNRVNDYLTINVKDYESTNSNRSIGKAVVPLSTIDPESDTTFNIPL
VGPKGEDGGVLHLEFEFEPRYTTNVVKREAGLGNFATKGLGTGIKAGSTVFALGTNVV
STGLGTIDKVKAGVFGGKKSTTTGDKKSEEKQ"
gene 466334..466642
/gene="SNN1"
/locus_tag="YNL086W"
/db_xref="GeneID:855638"
mRNA 466334..466642
/gene="SNN1"
/locus_tag="YNL086W"
/product="Snn1p"
/transcript_id="NM_001182924.1"
/db_xref="GI:296147679"
/db_xref="GeneID:855638"
CDS 466334..466642
/gene="SNN1"
/locus_tag="YNL086W"
/note="hypothetical protein; likely member of BLOC complex
involved in endosomal cargo sorting; green fluorescent
protein (GFP)-fusion protein localizes to endosomes"
/codon_start=1
/product="Snn1p"
/protein_id="NP_014313.1"
/db_xref="GI:6324243"
/db_xref="SGD:S000005030"
/db_xref="GeneID:855638"
/translation="MAGDSISADGTGVHPVELSVYSVLSTDLDGLYQSINELRESQAL
LILMLRKVRDKLRREGQVLYDPEPFKPTMDKLADLSARVRILSQRYEELQGNARALNN
"
gene 467131..469623
/gene="MKT1"
/locus_tag="YNL085W"
/db_xref="GeneID:855639"
mRNA 467131..469623
/gene="MKT1"
/locus_tag="YNL085W"
/product="Mkt1p"
/transcript_id="NM_001182923.3"
/db_xref="GI:398364956"
/db_xref="GeneID:855639"
CDS 467131..469623
/gene="MKT1"
/locus_tag="YNL085W"
/note="Protein that forms a complex with Pbp1p; complex
may mediate posttranscriptional regulation of HO; involved
in propagation of M2 dsRNA satellite of L-A virus; allelic
variation affects mitochondrial genome stability, drug
resistance, and more; forms cytoplasmic foci upon DNA
replication stress"
/codon_start=1
/product="Mkt1p"
/protein_id="NP_014314.3"
/db_xref="GI:398364957"
/db_xref="SGD:S000005029"
/db_xref="GeneID:855639"
/translation="MAIKSLESFLFERGLVGSYAIEALNNCTLDIDVNHYVSRLLTNK
REQYLDAIGGFPTSLKMYLESDLKIFKDFNITPIFVFNGGLTYNQLEASGHFTAASAS
ASISSTTTSSSGTNATTRSNTESVLLQRSRGWTQWNNLISSNQNSYIDQPIQPQEPFR
HNTTIDSKAYQNDLIAYFIEHGYMYQVAPYSSWFQLAYLLNSAYIDAIYGPTDCLMLD
CVDRFILGMEFPNKEFRFIDRSRVMKDLGCTHEEFIDIAMAVGNDLQPTTLPPLQIYP
VPQLFDIALEMVLNTGTNFYAYQLSTTLQNDSKENIQNYQRGISALRYMPVLKDTGKV
ELFVQEIVVSEEDSEKNNKDGKKSNLSSPSSASSSASPATTVTKNASEKLTYEKSSTK
EVRKPRDIPNDVHDFIGQMLPHEYYFYRSIGLVTGKLFDAIVTGVYPEEPPLGGGSST
SYKKLVSKSVEIFKNKEINLLTQPINRYYQIKQIKQVKWYAANEPTTLTNRMSPSMFE
TINHLIVKTETSDEKEFSISEFITTINGSSNMAKDFISEKVIFPNSVPIESKLNSPFN
LLSTNFLRLLVLLEFFTFDFKEKLLEPTRWGEVFLKLNELNIDSKYHESVIIFLVFLK
CDVLKLDEEVQPPAPSALSQATLRSYPEESLYVLLITRVLTLFQVDQKPSNYHGPIDK
KTLIFRDHLSFIKENLNELFEAVLISSLTSGEFNRLSLDNFGWARKIVRYLPFKLDSP
NTIMAMMWEFFLQKYLHNGNAKNDALSLVATEFNTYKSTPNLDEQFVESHRFLLEISK
VMQELNAAKLIDENVFKLFTKAVEFTTTALSS"
gene complement(470053..471102)
/gene="END3"
/locus_tag="YNL084C"
/db_xref="GeneID:855640"
mRNA complement(470053..471102)
/gene="END3"
/locus_tag="YNL084C"
/product="End3p"
/transcript_id="NM_001182922.1"
/db_xref="GI:296147681"
/db_xref="GeneID:855640"
CDS complement(470053..471102)
/gene="END3"
/locus_tag="YNL084C"
/note="EH domain-containing protein involved in
endocytosis, actin cytoskeletal organization and cell wall
morphogenesis; forms a complex with Sla1p and Pan1p"
/codon_start=1
/product="End3p"
/protein_id="NP_014315.1"
/db_xref="GI:6324245"
/db_xref="SGD:S000005028"
/db_xref="GeneID:855640"
/translation="MPKLEQFEIKKYWQIFSGLKPIENKVNHDQVLPILYNSKLDSSV
LNKIWFLADIDDDDNLDFEEFVICMRLIFDMVNKNISSVPDELPDWLIPGSKVNLIKE
RKKRKQIENADLPPKKEIKVDWYMSPDDLNQYEKIYNSCAKLTDGTITFNELSTKLST
KFFNISKTDLNKVWSLINPQNLPSIDRDPTFYFIHCLRQRNDLGAEIPASLPNSLAEV
CNKKQLSYDLRSSQPPTKRKEEANEVDNLRDNGQNSSSDSSGSNVLSNEDSIKQKYAS
LTDDQVANMREQLEGLLNYKKSEKTQGGSKLSKRINIRSITDDLDNIEQQVEVLENYL
NNKRHELQALQAEIN"
gene 471377..472861
/gene="SAL1"
/locus_tag="YNL083W"
/db_xref="GeneID:855641"
mRNA 471377..472861
/gene="SAL1"
/locus_tag="YNL083W"
/product="Sal1p"
/transcript_id="NM_001182921.1"
/db_xref="GI:296147682"
/db_xref="GeneID:855641"
CDS 471377..472861
/gene="SAL1"
/locus_tag="YNL083W"
/note="ADP/ATP transporter; member of the Ca2+-binding
subfamily of mitochondrial carriers, with two EF-hand
motifs; transport activity of either Sal1p or Pet9p is
critical for viability; polymorphic in different S.
cerevisiae strains"
/codon_start=1
/product="Sal1p"
/protein_id="NP_014316.3"
/db_xref="GI:296147683"
/db_xref="SGD:S000005027"
/db_xref="GeneID:855641"
/translation="MLLKNCETDKQRDIRYACLFKELDVKGNGQVTLDNLISAFEKND
HPLKGNDEAIKMLFTAMDVNKDSVVDLSDFKKYASNAESQIWNGFQRIDLDHDGKIGI
NEINRYLSDLDNQSICNNELNHELSNEKMNKFSRFFEWAFPKRKANIALRGQASHKKN
TDNDRSKKTTDSDLYVTYDQWRDFLLLVPRKQGSRLHTAYSYFYLFNEDVDLSSEGDV
TLINDFIRGFGFFIAGGISGVISRTCTAPFDRLKVFLIARTDLSSILLNSKTDLLAKN
PNADINKISSPLAKAVKSLYRQGGIKAFYVGNGLNVIKVFPESSIKFGSFEVTKKIMT
KLEGCRDTKDLSKFSTYIAGGLAGMAAQFSVYPIDTLKFRVQCAPLDTKLKGNNLLFQ
TAKDMFREGGGQIILQRCHSRYSGHISLCCIRFGDFFCLKKMVYCQTGKDPEPTTRSG
HSKQPGCTSNGCIQWNCRSFCCLSNQSFKNKTTSPRNICTSLCV"
gene 473391..476012
/gene="PMS1"
/locus_tag="YNL082W"
/db_xref="GeneID:855642"
mRNA 473391..476012
/gene="PMS1"
/locus_tag="YNL082W"
/product="Pms1p"
/transcript_id="NM_001182920.3"
/db_xref="GI:398364980"
/db_xref="GeneID:855642"
CDS 473391..476012
/gene="PMS1"
/locus_tag="YNL082W"
/note="ATP-binding protein required for mismatch repair in
mitosis and meiosis; functions as a heterodimer with
Mlh1p, binds double- and single-stranded DNA via its
N-terminal domain, similar to E. coli MutL"
/codon_start=1
/product="Pms1p"
/protein_id="NP_014317.4"
/db_xref="GI:398364981"
/db_xref="SGD:S000005026"
/db_xref="GeneID:855642"
/translation="MTQIHQINDIDVHRITSGQVITDLTTAVKELVDNSIDANANQIE
IIFKDYGLESIECSDNGDGIDPSNYEFLALKHYTSKIAKFQDVAKVQTLGFRGEALSS
LCGIAKLSVITTTSPPKADKLEYDMVGHITSKTTTSRNKGTTVLVSQLFHNLPVRQKE
FSKTFKRQFTKCLTVIQGYAIINAAIKFSVWNITPKGKKNLILSTMRNSSMRKNISSV
FGAGGMRGLEEVDLVLDLNPFKNRMLGKYTDDPDFLDLDYKIRVKGYISQNSFGCGRN
SKDRQFIYVNKRPVEYSTLLKCCNEVYKTFNNVQFPAVFLNLELPMSLIDVNVTPDKR
VILLHNERAVIDIFKTTLSDYYNRQELALPKRMCSQSEQQAQKRLKTEVFDDRSTTHE
SDNENYHTARSESNQSNHAHFNSTTGVIDKSNGTELTSVMDGNYTNVTDVIGSECEVS
VDSSVVLDEGNSSTPTKKLPSIKTDSQNLSDLNLNNFSNPEFQNITSPDKARSLEKVV
EEPVYFDIDGEKFQEKAVLSQADGLVFVDNECHEHTNDCCHQERRGSTDTEQDDEADS
IYAEIEPVEINVRTPLKNSRKSISKDNYRSLSDGLTHRKFEDEILEYNLSTKNFKEIS
KNGKQMSSIISKRKSEAQENIIKNKDELEDFEQGEKYLTLTVSKNDFKKMEVVGQFNL
GFIIVTRKVDNKYDLFIVDQHASDEKYNFETLQAVTVFKSQKLIIPQPVELSVIDELV
VLDNLPVFEKNGFKLKIDEEEEFGSRVKLLSLPTSKQTLFDLGDFNELIHLIKEDGGL
RRDNIRCSKIRSMFAMRACRSSIMIGKPLNKKTMTRVVHNLSELDKPWNCPHGRPTMR
HLMELRDWSSFSKDYEI"
gene complement(476188..476619)
/gene="SWS2"
/locus_tag="YNL081C"
/db_xref="GeneID:855643"
mRNA complement(476188..476619)
/gene="SWS2"
/locus_tag="YNL081C"
/product="putative mitochondrial 37S ribosomal protein
SWS2"
/transcript_id="NM_001182919.3"
/db_xref="GI:398364984"
/db_xref="GeneID:855643"
CDS complement(476188..476619)
/gene="SWS2"
/locus_tag="YNL081C"
/note="Putative mitochondrial ribosomal protein of the
small subunit, has similarity to E. coli S13 ribosomal
protein; participates in controlling sporulation
efficiency"
/codon_start=1
/product="putative mitochondrial 37S ribosomal protein
SWS2"
/protein_id="NP_014318.3"
/db_xref="GI:398364985"
/db_xref="SGD:S000005025"
/db_xref="GeneID:855643"
/translation="MVVHILGKGFKGKEVIKIALASKFYGIGKTTAEKICSKLGFYPW
MRMHQLSEPQIMSIASELSTMTIEGDARAIVKDNIALKRKIGSYSGMRHTLHLPVRGQ
HTRNNAKTARKLNKIDRRGIHTFSQAKVQHNPSLWSCIFGK"
gene complement(476932..478032)
/gene="EOS1"
/locus_tag="YNL080C"
/db_xref="GeneID:855644"
mRNA complement(476932..478032)
/gene="EOS1"
/locus_tag="YNL080C"
/product="Eos1p"
/transcript_id="NM_001182918.1"
/db_xref="GI:296147686"
/db_xref="GeneID:855644"
CDS complement(476932..478032)
/gene="EOS1"
/locus_tag="YNL080C"
/note="Protein involved in N-glycosylation; deletion
mutation confers sensitivity to exidative stress and shows
synthetic lethality with mutations in the spindle
checkpoint genes BUB3 and MAD1; YNL080C is not an
essential gene"
/codon_start=1
/product="Eos1p"
/protein_id="NP_014319.1"
/db_xref="GI:6324249"
/db_xref="SGD:S000005024"
/db_xref="GeneID:855644"
/translation="MTWILSTGMGPHEDKYAKHERATFKKTYSSMKTLSLNHLTAKQH
MLMALCRDISLLPPLTYIFTSLRKAWRVSMRTSITLYEPQSLRDAFTYFWQKLNSAYD
NNSSFEGASQKAVNGDGKDSLLLSALTTARASEYLLCSLWCLVSLYLSYAILDSLMVR
WIVKYSTVAAILRMFSMSLIIVTLELLLLSSLSPELDYFLHTWILISCVLTAVYIWQS
YLTSDLRYIRNQEGEVQEDTNVPEETEDYEDGEDDADEDSHVVVADESTVDVPSNDSL
SDNSDGGLFPVNRPSVSHSQSPKRPKKYPKKAFNFTTKRTIDLYKITVLCVVPVGLAS
FITMLGLLRNLFIQRLDVEQLERILHEMHPPA"
gene complement(478566..479165)
/gene="TPM1"
/locus_tag="YNL079C"
/db_xref="GeneID:855645"
mRNA complement(478566..479165)
/gene="TPM1"
/locus_tag="YNL079C"
/product="Tpm1p"
/transcript_id="NM_001182917.1"
/db_xref="GI:296147687"
/db_xref="GeneID:855645"
CDS complement(478566..479165)
/gene="TPM1"
/locus_tag="YNL079C"
/note="Major isoform of tropomyosin; binds to and
stabilizes actin cables and filaments, which direct
polarized cell growth and the distribution of several
organelles; acetylated by the NatB complex and acetylated
form binds actin most efficiently"
/codon_start=1
/product="Tpm1p"
/protein_id="NP_014320.1"
/db_xref="GI:6324250"
/db_xref="SGD:S000005023"
/db_xref="GeneID:855645"
/translation="MDKIREKLSNLKLEAESWQEKYEELKEKNKDLEQENVEKENQIK
SLTVKNQQLEDEIEKLEAGLSDSKQTEQDNVEKENQIKSLTVKNHQLEEEIEKLEAEL
AESKQLSEDSHHLQSNNDNFSKKNQQLEEDLEESDTKLKETTEKLRESDLKADQLERR
VAALEEQREEWERKNEELTVKYEDAKKELDEIAASLENL"
gene 479768..480991
/gene="NIS1"
/locus_tag="YNL078W"
/gene_synonym="JIP1"
/db_xref="GeneID:855646"
mRNA 479768..480991
/gene="NIS1"
/locus_tag="YNL078W"
/gene_synonym="JIP1"
/product="Nis1p"
/transcript_id="NM_001182916.3"
/db_xref="GI:398365010"
/db_xref="GeneID:855646"
CDS 479768..480991
/gene="NIS1"
/locus_tag="YNL078W"
/gene_synonym="JIP1"
/note="Protein localized in the bud neck at G2/M phase;
physically interacts with septins; possibly involved in a
mitotic signaling network"
/codon_start=1
/product="Nis1p"
/protein_id="NP_014321.3"
/db_xref="GI:398365011"
/db_xref="SGD:S000005022"
/db_xref="GeneID:855646"
/translation="METYETSIGTQSYPPTLFPPPLGTGGFTTSGYIHALVDSTSNSN
SNSNTNSNTNSNTNSNSDTKIPIVQISDDSHITHDSFKPYMEYHDASHLRNRNISKAD
QVESTEVMEQFTQWSNYKMRSRSPTINAKPIRHTSQRRTDFTSKNELSKFSKNHNFIF
HKGFLKRQHSIRREDRQAKVRSRFRSKKELTSVLNYIELEQMDIANVLASQPVNLHAI
RNLTSRDPAVTPIPFLRSQMYATSSRPPYLRNRSISRKLPKSQPGSLPTTMPATATKT
IKQNSTTPTTRSVYNKNVGRSNTSPSVLYHPKRRGKLNTKSHARKEQLLLELWREYLM
LVITQRTQLRLTLLCSPGSASNESSVCSSNASDLDMSLLSTPSSLFQMAGETKSNPII
IPDSQDDSILSSDPF"
gene 481391..482977
/gene="APJ1"
/locus_tag="YNL077W"
/db_xref="GeneID:855647"
mRNA 481391..482977
/gene="APJ1"
/locus_tag="YNL077W"
/product="Apj1p"
/transcript_id="NM_001182915.1"
/db_xref="GI:296147689"
/db_xref="GeneID:855647"
CDS 481391..482977
/gene="APJ1"
/locus_tag="YNL077W"
/note="Putative chaperone of the HSP40 (DNAJ) family;
overexpression interferes with propagation of the [Psi+]
prion; the authentic, non-tagged protein is detected in
highly purified mitochondria in high-throughput studies;
forms nuclear foci upon DNA replication stress"
/codon_start=1
/product="Apj1p"
/protein_id="NP_014322.1"
/db_xref="GI:6324252"
/db_xref="SGD:S000005021"
/db_xref="GeneID:855647"
/translation="MQQNTSLYDSLNVTAAASTSEIKKAYRNAALKYHPDKNNHTEES
KRKFQEICQAYEILKDNRLRALYDQYGTTDEVLIQEQQAQAQRQQAGPFSSSSNFDTE
AMSFPDLSPGDLFAQFFNSSATPSSNGSKSSFNFSFNNSSTPSFSFVNGSGVNNLYSS
SAKYNSNDEDHHLDRGPDIKHNLKCTLKELYMGKTAKLGLNRTRICSVCDGHGGLKKC
TCKTCKGQGIQTQTRRMGPLVQSWSQTCADCGGAGVFVKNKDICQQCQGLGFIKERKI
LQVTVQPGSCHNQLIVLTGEGDEVISTKGGGHEKVIPGDVVITILRLKDPNFQVINYS
NLICKKCKIDFMTSLCGGVVYIEGHPSGKLIKLDIIPGEILKPGCFKTVEDMGMPKFI
NGVRSGFGHLYVKFDVTYPERLEPENAKKIQNILANDKYIKAERSTMETADSDCYCDL
EKSYDSVEEHVLSSFEAPNLNNEVIEDDDLGDLINERDSRKRNNRRFDESNINNNNET
KRNKYSSPVSGFYDHDINGY"
gene 483556..485310
/gene="MKS1"
/locus_tag="YNL076W"
/gene_synonym="LYS80"
/db_xref="GeneID:855648"
mRNA 483556..485310
/gene="MKS1"
/locus_tag="YNL076W"
/gene_synonym="LYS80"
/product="Mks1p"
/transcript_id="NM_001182914.1"
/db_xref="GI:296147690"
/db_xref="GeneID:855648"
CDS 483556..485310
/gene="MKS1"
/locus_tag="YNL076W"
/gene_synonym="LYS80"
/note="Pleiotropic negative transcriptional regulator
involved in Ras-CAMP and lysine biosynthetic pathways and
nitrogen regulation; involved in retrograde (RTG)
mitochondria-to-nucleus signaling"
/codon_start=1
/product="Mks1p"
/protein_id="NP_014323.1"
/db_xref="GI:6324253"
/db_xref="SGD:S000005020"
/db_xref="GeneID:855648"
/translation="MSREAFDVPNIGTNKFLKVTPNLFTPERLNLFDDVELYLTLIKA
SKCVEQGERLHNISWRILNKAVLKEHNINRSKKRDGVKNIYYVLNPNNKQPIKPKQAA
VKQPPLQKANLPPTTAKQNVLTRPMTSPAIAQGAHDRSLDNPNSTNNDVKNDVAPNRQ
FSKSTTSGLFSNFADKYQKMKNVNHVANKEEPQTIITGFDTSTVITKKPLQSRRSRSP
FQHIGDMNMNCIDNETSKSTSPTLENMGSRKSSFPQKESLFGRPRSYKNDQNGQLSLS
KTSSRKGKNKIFFSSEDEDSDWDSVSNDSEFYADEDDEEYDDYNEEEADQYYRRQWDK
LLFAKNQQNLDSTKSSVSSANTINSNTSHDPVRKSLLSGLFLSEANSNSNNHNTAHSE
YASKHVSPTPQSSHSNIGPQPQQNPPSANGIKQQKPSLKTSNVTALASLSPPQPSNNE
RLSMDIQKDFKTDNESNHLYESNAPLTAQTILPTALSTHMFLPNNIHQQRMAIATGSN
TRHRFSRRQSMDIPSKNRNTGFLKTRMEISEEEKMVRTISRLDNTSIANSNGNGNDDT
SNQRTEALGRKTSNGGRI"
gene 485607..486479
/gene="IMP4"
/locus_tag="YNL075W"
/db_xref="GeneID:855649"
mRNA 485607..486479
/gene="IMP4"
/locus_tag="YNL075W"
/product="Imp4p"
/transcript_id="NM_001182913.3"
/db_xref="GI:398365038"
/db_xref="GeneID:855649"
CDS 485607..486479
/gene="IMP4"
/locus_tag="YNL075W"
/note="Component of the SSU processome, which is required
for pre-18S rRNA processing; interacts with Mpp10p; member
of a superfamily of proteins that contain a sigma(70)-like
motif and associate with RNAs"
/codon_start=1
/product="Imp4p"
/protein_id="NP_014324.3"
/db_xref="GI:398365039"
/db_xref="SGD:S000005019"
/db_xref="GeneID:855649"
/translation="MLRRQARERREYLYRKAQELQDSQLQQKRQIIKQALAQGKPLPK
ELAEDESLQKDFRYDQSLKESEEADDLQVDDEYAATSGIMDPRIIVTTSRDPSTRLSQ
FAKEIKLLFPNAVRLNRGNYVMPNLVDACKKSGTTDLVVLHEHRGVPTSLTISHFPHG
PTAQFSLHNVVMRHDIINAGNQSEVNPHLIFDNFTTALGKRVVCILKHLFNAGPKKDS
ERVITFANRGDFISVRQHVYVRTREGVEIAEVGPRFEMRLFELRLGTLENKDADVEWQ
LRRFIRTANKKDYL"
gene complement(486766..488124)
/gene="MLF3"
/locus_tag="YNL074C"
/gene_synonym="YMK1"
/db_xref="GeneID:855650"
mRNA complement(486766..488124)
/gene="MLF3"
/locus_tag="YNL074C"
/gene_synonym="YMK1"
/product="Mlf3p"
/transcript_id="NM_001182912.3"
/db_xref="GI:398365050"
/db_xref="GeneID:855650"
CDS complement(486766..488124)
/gene="MLF3"
/locus_tag="YNL074C"
/gene_synonym="YMK1"
/note="Serine-rich hypothetical protein, predicted to be
palmitoylated; overproduction suppresses the growth
inhibition caused by exposure to the immunosuppressant
leflunomide"
/codon_start=1
/product="Mlf3p"
/protein_id="NP_014325.3"
/db_xref="GI:398365051"
/db_xref="SGD:S000005018"
/db_xref="GeneID:855650"
/translation="MCVYKSNSNNSNPSFIFERTVQEASSNDLFLQPPVSASNTSHSS
RSNSFYNLQTISPIPISGSEVRTPSLRKNSNNVSSPLDNVIPTSRSASNSTTSSLAHQ
EYILNPICNMQNHHHRRRTLENSVAPALDASCSIVNDENTDLSDVDMVYSRRPSSAVS
LNMALLARTNSATLPSSESSPASPDLKLSRSHSHSAATRPTLNNINNTGMTTTTSNGE
PNSRILRFYSYVDMLNDEKLAQANNTPTSRPPMKSQAYSCPFILKRSPPQAYSSSSAT
TTFSNPFIKTTELPATSPYVSPQQSARQYSNNANNNAKSPKNRSSSILFQRQSILSNV
DPVANMHKNPKFQIESSDSEEEDLTMDMLDPSFPLSSSLRSSANLASNPELATQTPLS
TSSSYTAIGKPMPLSTDPSYVSSSNTLSSEHELRVEKVSEVLKKKVSNGGFSTEFNSC
DT"
gene 488386..490116
/gene="MSK1"
/locus_tag="YNL073W"
/db_xref="GeneID:855651"
mRNA 488386..490116
/gene="MSK1"
/locus_tag="YNL073W"
/product="lysine--tRNA ligase MSK1"
/transcript_id="NM_001182911.1"
/db_xref="GI:296147693"
/db_xref="GeneID:855651"
CDS 488386..490116
/gene="MSK1"
/locus_tag="YNL073W"
/EC_number="6.1.1.6"
/note="Mitochondrial lysine-tRNA synthetase, required for
import of both aminoacylated and deacylated forms of
tRNA(Lys) into mitochondria and for aminoacylation of
mitochondrially encoded tRNA(Lys)"
/codon_start=1
/product="lysine--tRNA ligase MSK1"
/protein_id="NP_014326.1"
/db_xref="GI:6324256"
/db_xref="SGD:S000005017"
/db_xref="GeneID:855651"
/translation="MNVLLKRRSLTFAPRWLWCKCRSSRSRPYSLAHAVDTSKMEATR
RNGQIVKDLGRYYPSMSESALHDLCQEYKEVTIADFNERFLGNPATLHHEDNPNLLLS
INGRIKSIRFSGQKIVFIDLYNGSSGLKNDTQLQLIVNYNKIGGSSEDKANFSEYMNF
LKKGDYIKALGYPGFSQSRVKMLSLICNKLPIVLSVSQLPLPSRLNDETKIKSNRVVD
YQLNGTQTLLVRARIIKLLRKFLDDRNFVEVETPILSSKSNGAMAKPFITSSKDFDHL
ELRIAPELWLKRLIISGLQKVYEIGKVFRNEGIDSTHNAEFSTLEFYETYMSMDDIVT
RTEDLFKFLITNLQKFFQDTRLPVPKTFSELHLALSENNWKFRKVEFLPTLNKELGID
LMNSGLDINKPSELLKALPKDIAKKYFPSADNTGQLSSLQILNKLSDVFLEQRHCQST
LPTVIYHQPAILSPLAKTDPQNKQVTKRFEVFIKGKEYINAYEEENCPQLQLQKFLQQ
KQINELTGNKTETLSPVIDYQYVETMKYGMPPVGGFGLGIDRLCMLFCDKKRIEEVLP
FGCVDDVNRQ"
gene 490317..491240
/gene="RNH201"
/locus_tag="YNL072W"
/gene_synonym="RNH35"
/db_xref="GeneID:855652"
mRNA 490317..491240
/gene="RNH201"
/locus_tag="YNL072W"
/gene_synonym="RNH35"
/product="Rnh201p"
/transcript_id="NM_001182910.1"
/db_xref="GI:296147694"
/db_xref="GeneID:855652"
CDS 490317..491240
/gene="RNH201"
/locus_tag="YNL072W"
/gene_synonym="RNH35"
/EC_number="3.1.26.4"
/note="Ribonuclease H2 catalytic subunit, removes RNA
primers during Okazaki fragment synthesis and errant
ribonucleotides misincorporated during DNA replication;
homolog of RNAse HI; related to human AGS4 which causes
Aicardi-Goutieres syndrome"
/codon_start=1
/product="Rnh201p"
/protein_id="NP_014327.1"
/db_xref="GI:6324257"
/db_xref="SGD:S000005016"
/db_xref="GeneID:855652"
/translation="MVPPTVEASLESPYTKSYFSPVPSALLEQNDSPIIMGIDEAGRG
PVLGPMVYAVAYSTQKYQDETIIPNYEFDDSKKLTDPIRRMLFSKIYQDNEELTQIGY
ATTCITPLDISRGMSKFPPTRNYNLNEQAHDVTMALIDGVIKQNVKLSHVYVDTVGPP
ASYQKKLEQRFPGVKFTVAKKADSLYCMVSVASVVAKVTRDILVESLKRDPDEILGSG
YPSDPKTVAWLKRNQTSLMGWPANMVRFSWQTCQTLLDDASKNSIPIKWEEQYMDSRK
NAAQKTKQLQLQMVAKPVRRKRLRTLDNWYR"
gene 491523..492971
/gene="LAT1"
/locus_tag="YNL071W"
/gene_synonym="ODP2; PDA2"
/db_xref="GeneID:855653"
mRNA 491523..492971
/gene="LAT1"
/locus_tag="YNL071W"
/gene_synonym="ODP2; PDA2"
/product="dihydrolipoyllysine-residue acetyltransferase"
/transcript_id="NM_001182909.3"
/db_xref="GI:398365062"
/db_xref="GeneID:855653"
CDS 491523..492971
/gene="LAT1"
/locus_tag="YNL071W"
/gene_synonym="ODP2; PDA2"
/EC_number="2.3.1.12"
/note="Dihydrolipoamide acetyltransferase component (E2)
of pyruvate dehydrogenase complex, which catalyzes the
oxidative decarboxylation of pyruvate to acetyl-CoA"
/codon_start=1
/product="dihydrolipoyllysine-residue acetyltransferase"
/protein_id="NP_014328.3"
/db_xref="GI:398365063"
/db_xref="SGD:S000005015"
/db_xref="GeneID:855653"
/translation="MSAFVRVVPRISRSSVLTRSLRLQLRCYASYPEHTIIGMPALSP
TMTQGNLAAWTKKEGDQLSPGEVIAEIETDKAQMDFEFQEDGYLAKILVPEGTKDIPV
NKPIAVYVEDKADVPAFKDFKLEDSGSDSKTSTKAQPAEPQAEKKQEAPAEETKTSAP
EAKKSDVAAPQGRIFASPLAKTIALEKGISLKDVHGTGPRGRITKADIESYLEKSSKQ
SSQTSGAAAATPAAATSSTTAGSAPSPSSTASYEDVPISTMRSIIGERLLQSTQGIPS
YIVSSKISISKLLKLRQSLNATANDKYKLSINDLLVKAITVAAKRVPDANAYWLPNEN
VIRKFKNVDVSVAVATPTGLLTPIVKNCEAKGLSQISNEIKELVKRARINKLAPEEFQ
GGTICISNMGMNNAVNMFTSIINPPQSTILAIATVERVAVEDAAAENGFSFDNQVTIT
GTFDHRTIDGAKGAEFMKELKTVIENPLEMLL"
gene 493366..493548
/gene="TOM7"
/locus_tag="YNL070W"
/gene_synonym="MOM7; YOK22"
/db_xref="GeneID:855654"
mRNA 493366..493548
/gene="TOM7"
/locus_tag="YNL070W"
/gene_synonym="MOM7; YOK22"
/product="Tom7p"
/transcript_id="NM_001182908.1"
/db_xref="GI:296147696"
/db_xref="GeneID:855654"
CDS 493366..493548
/gene="TOM7"
/locus_tag="YNL070W"
/gene_synonym="MOM7; YOK22"
/note="Component of the TOM (translocase of outer
membrane) complex responsible for recognition and initial
import steps for all mitochondrially directed proteins;
promotes assembly and stability of the TOM complex"
/codon_start=1
/product="Tom7p"
/protein_id="NP_014329.1"
/db_xref="GI:6324259"
/db_xref="SGD:S000005014"
/db_xref="GeneID:855654"
/translation="MSFLPSFILSDESKERISKILTLTHNVAHYGWIPFVLYLGWAHT
SNRPNFLNLLSPLPSV"
gene complement(493956..495001)
/gene="RPL16B"
/locus_tag="YNL069C"
/gene_synonym="RP23"
/db_xref="GeneID:855655"
mRNA complement(join(493956..494524,494974..495001))
/gene="RPL16B"
/locus_tag="YNL069C"
/gene_synonym="RP23"
/product="ribosomal 60S subunit protein L16B"
/transcript_id="NM_001182907.1"
/db_xref="GI:296147697"
/db_xref="GeneID:855655"
CDS complement(join(493956..494524,494974..495001))
/gene="RPL16B"
/locus_tag="YNL069C"
/gene_synonym="RP23"
/note="Ribosomal 60S subunit protein L16B; N-terminally
acetylated, binds 5.8 S rRNA; transcriptionally regulated
by Rap1p; homologous to mammalian ribosomal protein L13A
and bacterial L13; RPL16B has a paralog, RPL16A, that
arose from the whole genome duplication"
/codon_start=1
/product="ribosomal 60S subunit protein L16B"
/protein_id="NP_014330.1"
/db_xref="GI:6324260"
/db_xref="SGD:S000005013"
/db_xref="GeneID:855655"
/translation="MSQPVVVIDAKDHLLGRLASTIAKQVLNGQKIVVVRAEALNISG
EFFRNKLKYHDFLRKATAFNKTRGPFHFRAPSRILYKAIRGMVSHKTARGKAALERLK
IFEGIPPPYDKKKRVVVPQALRVLRLKPGRKYTTLGKLSTSVGWKYEDVVAKLEDKRK
VRSAEYYAKKRAFTKKVSSASAAASESDVAKQLASFGY"
gene complement(495701..498289)
/gene="FKH2"
/locus_tag="YNL068C"
/db_xref="GeneID:855656"
mRNA complement(495701..498289)
/gene="FKH2"
/locus_tag="YNL068C"
/product="Fkh2p"
/transcript_id="NM_001182906.3"
/db_xref="GI:398365088"
/db_xref="GeneID:855656"
CDS complement(495701..498289)
/gene="FKH2"
/locus_tag="YNL068C"
/note="Forkhead family transcription factor; plays a major
role in the expression of G2/M phase genes; positively
regulates transcriptional elongation; negative role in
chromatin silencing at HML and HMR; substrate of the
Cdc28p/Clb5p kinase; FKH2 has a paralog, FKH1, that arose
from the whole genome duplication"
/codon_start=1
/product="Fkh2p"
/protein_id="NP_014331.3"
/db_xref="GI:398365089"
/db_xref="SGD:S000005012"
/db_xref="GeneID:855656"
/translation="MSSSNFNEMNELNMTQTNYGSTKYTAQHHQGVINAIISSLTAPD
QPTTVSLQYSNDKNMATEIQAYAKLSGPNWTYYVKDLEVSIGRNTDPLNSALQENSDG
VKNSYRVNIDLGPAKVVSRKHAIIKYNMNIGGWELHILGRNGAKVNFQRTHNGPNNPP
IRLSSGTLLDIGGTQMMFILPDSDPVVAPICIEHLMPNLINMFGLEGNNNPLLRDIIK
QSNYAKQRQLTSNQQIKGFKLYGSGGNAPFGSGANLGPSEQGIFNNNNNSKNKNGYFT
SINPNYTASTTTSNTINPQAASPQGPPNTIIAANFVDSYKSSNAYPQALDFTSDLSHD
ENRNVKPPHSYATMITQAILSSPEGVISLADIYKYISSNYAYYRFAKSGWQNSIRHNL
SLNKAFEKVPRRPNEPGKGMKWRISESYQQEFLNKWNTGKVGKIRRGSSVARQLQLHM
AKFNSLPMEMDYRLSLNMAQPPKRQLQSHNVLEPSNNNIIEGFVQHVPSKGNLPASQQ
SQPPVSHQNQSQQPPPQEQRQEIQFTFADTQNRNIALARPIKTPQLQAPNSNANLNQN
NMKEYKESLHPPAISISQMNRQSPNNALVSFTNACANSKIINNISDSADKSTNNNGGT
KMNLPAISTSSLDENGNLEPTTTTSSGNSNSVPQTGTTTSSLAANSLRLSQPYDTLLR
SPTKAFHITAMEAYTPERGSANRARSPLHSNSNNTNNNGANNSNLQTSGMENKQTGLV
LDSNVLKSMESNNDNRRLTPSTSKSQNVKSSPGVWNLLQFSSTNNTPAADSGGNKRGF
SINPDIKAKENENATSEKDSDSNSNDLETKDINSSPLKNQGGSTANAKELILDTDGAK
ISIINN"
rep_origin 498991..499235
/note="ARS1420;
Autonomously Replicating Sequence"
/db_xref="SGD:S000118388"
gene 499417..499557
/locus_tag="YNL067W-B"
/gene_synonym="YNL067W-A"
/db_xref="GeneID:1466514"
mRNA 499417..499557
/locus_tag="YNL067W-B"
/gene_synonym="YNL067W-A"
/product="hypothetical protein"
/transcript_id="NM_001184639.3"
/db_xref="GI:398365098"
/db_xref="GeneID:1466514"
CDS 499417..499557
/locus_tag="YNL067W-B"
/gene_synonym="YNL067W-A"
/codon_start=1
/product="hypothetical protein"
/protein_id="NP_878156.3"
/db_xref="GI:398365099"
/db_xref="SGD:S000028810"
/db_xref="GeneID:1466514"
/translation="MCKLMWCTGVVSKTALLTGNFFFSSSEFFFKATHRKSENYLNGR
QT"
gene 499681..500256
/gene="RPL9B"
/locus_tag="YNL067W"
/db_xref="GeneID:855658"
mRNA 499681..500256
/gene="RPL9B"
/locus_tag="YNL067W"
/product="ribosomal 60S subunit protein L9B"
/transcript_id="NM_001182905.1"
/db_xref="GI:296147700"
/db_xref="GeneID:855658"
CDS 499681..500256
/gene="RPL9B"
/locus_tag="YNL067W"
/note="Ribosomal 60S subunit protein L9B; nearly identical
to Rpl9Ap; homologous to mammalian ribosomal protein L9
and bacterial L6"
/codon_start=1
/product="ribosomal 60S subunit protein L9B"
/protein_id="NP_014332.1"
/db_xref="GI:6324262"
/db_xref="SGD:S000005011"
/db_xref="GeneID:855658"
/translation="MKYIQTEQQIEIPEGVTVSIKSRIVKVVGPRGTLTKNLKHIDVT
FTKVNNQLIKVAVHNGDRKHVAALRTVKSLVDNMITGVTKGYKYKMRYVYAHFPINVN
IVEKDGAKFIEVRNFLGDKKIRNVPVRDGVTIEFSTNVKDEIVLSGNSVEDVSQNAAD
LQQICRVRNKDIRKFLDGIYVSHKGFIVEDM"
gene 501515..502777
/gene="SUN4"
/locus_tag="YNL066W"
/gene_synonym="SCW3"
/db_xref="GeneID:855659"
mRNA 501515..502777
/gene="SUN4"
/locus_tag="YNL066W"
/gene_synonym="SCW3"
/product="Sun4p"
/transcript_id="NM_001182904.1"
/db_xref="GI:296147701"
/db_xref="GeneID:855659"
CDS 501515..502777
/gene="SUN4"
/locus_tag="YNL066W"
/gene_synonym="SCW3"
/note="Cell wall protein related to glucanases, possibly
involved in cell wall septation; member of the SUN family"
/codon_start=1
/product="Sun4p"
/protein_id="NP_014333.1"
/db_xref="GI:6324263"
/db_xref="SGD:S000005010"
/db_xref="GeneID:855659"
/translation="MKLSATTLTAASLIGYSTIVSALPYAADIDTGCTTTAHGSHQHK
RAVAVTYVYETVTVDKNGQTVTPTSTEASSTVASTTTLISESSVTKSSSKVASSSEST
EQIATTSSSAQTTLTSSETSTSESSVPISTSGSASTSSAASSATGSIYGDLADFSGPY
EKFEDGTIPCGQFPSGQGVIPISWLDEGGWSGVENTDTSTGGSCKEGSYCSYACQPGM
SKTQWPSDQPSDGRSIGGLLCKDGYLYRSNTDTDYLCEWGVDAAYVVSELSNDVAICR
TDYPGTENMVIPTYVQAGDSLPLTVVDQDTYYTWQGLKTSAQYYVNNAGISVEDACVW
GSSSSGVGNWAPLNFGAGSSDGVAYLSLIPNPNNGNALNFNVKIVAADDSSTVNGECI
YENGSFSGGSDGCTVSVTAGKAKFVLYN"
gene 503724..505484
/gene="AQR1"
/locus_tag="YNL065W"
/db_xref="GeneID:855660"
mRNA 503724..505484
/gene="AQR1"
/locus_tag="YNL065W"
/product="Aqr1p"
/transcript_id="NM_001182903.3"
/db_xref="GI:398365122"
/db_xref="GeneID:855660"
CDS 503724..505484
/gene="AQR1"
/locus_tag="YNL065W"
/note="Plasma membrane transporter of the major
facilitator superfamily; member of the 12-spanner
drug:H(+) antiporter DHA1 family; confers resistance to
short-chain monocarboxylic acids and quinidine; involved
in the excretion of excess amino acids; AQR1 has a
paralog, QDR1, that arose from the whole genome
duplication; relocalizes from plasma membrane to cytoplasm
upon DNA replication stress"
/codon_start=1
/product="Aqr1p"
/protein_id="NP_014334.3"
/db_xref="GI:398365123"
/db_xref="SGD:S000005009"
/db_xref="GeneID:855660"
/translation="MSRSNSIYTEDIEMYPTHNEQHLTREYTKPDGQTKSEKLNFEGA
YINSHGTLSKTTTREIEGDLDSETSSHSSDDKVDPTQQITAETKAPYTLLSYGQKWGM
VAILTMCGFWSSLGSPIYYPALRQLEKQFNVDENMVNVTVVVYLLFQGISPTVSGGLA
DCFGRRPIILAGMLIYVIASIGLACAPSYGVIIFLRCIQSIGISPTIAISSGVVGDFT
LKHERGTFVGATSGFVLLGQCFGSLIGAVLTARWDWRAIFWFLTIGCGSCFLIAFLIL
PETKRTIAGNLSIKPKRFINRAPIFLLGPVRRRFKYDNPDYETLDPTIPKLDLSSAGK
ILVLPEIILSLFPSGLLFAMWTLMLSSISSGLSVAPYNYHLVIIGVCYLPGGIGGLMG
SFFTGRIIDMYFKRKIKKFEQDKANGLIPQDAEINMFKVRLVCLLPQNFLAVVAYLLF
GWSIDKGWRIESILITSFVCSYCAMSTLSTSTTLLVDLYPTKSSTASSCFNFVRCSLS
TIFMGCFAKMKAAMTVGGTFTFLCALVFFFNFLMFIPMKYGMKWREDRLLKQQRQSWL
NTLAVKAKKGTKRDQNDNHN"
gene complement(505868..507097)
/gene="YDJ1"
/locus_tag="YNL064C"
/gene_synonym="HSP40; MAS5"
/db_xref="GeneID:855661"
mRNA complement(505868..507097)
/gene="YDJ1"
/locus_tag="YNL064C"
/gene_synonym="HSP40; MAS5"
/product="Ydj1p"
/transcript_id="NM_001182902.1"
/db_xref="GI:296147703"
/db_xref="GeneID:855661"
CDS complement(505868..507097)
/gene="YDJ1"
/locus_tag="YNL064C"
/gene_synonym="HSP40; MAS5"
/note="Type I HSP40 co-chaperone; involved in regulation
of HSP90 and HSP70 functions; critical for determining
cell size at Start as a function of growth rate; involved
in protein translocation across membranes; member of the
DnaJ family"
/codon_start=1
/product="Ydj1p"
/protein_id="NP_014335.1"
/db_xref="GI:6324265"
/db_xref="SGD:S000005008"
/db_xref="GeneID:855661"
/translation="MVKETKFYDILGVPVTATDVEIKKAYRKCALKYHPDKNPSEEAA
EKFKEASAAYEILSDPEKRDIYDQFGEDGLSGAGGAGGFPGGGFGFGDDIFSQFFGAG
GAQRPRGPQRGKDIKHEISASLEELYKGRTAKLALNKQILCKECEGRGGKKGAVKKCT
SCNGQGIKFVTRQMGPMIQRFQTECDVCHGTGDIIDPKDRCKSCNGKKVENERKILEV
HVEPGMKDGQRIVFKGEADQAPDVIPGDVVFIVSERPHKSFKRDGDDLVYEAEIDLLT
AIAGGEFALEHVSGDWLKVGIVPGEVIAPGMRKVIEGKGMPIPKYGGYGNLIIKFTIK
FPENHFTSEENLKKLEEILPPRIVPAIPKKATVDECVLADFDPAKYNRTRASRGGANY
DSDEEEQGGEGVQCASQ"
gene 507758..508702
/gene="MTQ1"
/locus_tag="YNL063W"
/db_xref="GeneID:855662"
mRNA 507758..508702
/gene="MTQ1"
/locus_tag="YNL063W"
/product="Mtq1p"
/transcript_id="NM_001182901.1"
/db_xref="GI:296147704"
/db_xref="GeneID:855662"
CDS 507758..508702
/gene="MTQ1"
/locus_tag="YNL063W"
/EC_number="2.1.1.-"
/note="S-adenosylmethionine-dependent methyltransferase;
methylates translational release factor Mrf1p; similar to
E.coli PrmC; is not an essential gene"
/codon_start=1
/product="Mtq1p"
/protein_id="NP_014336.1"
/db_xref="GI:6324266"
/db_xref="SGD:S000005007"
/db_xref="GeneID:855662"
/translation="MPRISTSLIRKASRIRPGLHLLLPECRTLEQAKLEYKWLTEELP
PDKSIRWACLQRYKHVPLQYILRSQPFGALDIVCKPGVLIPRWETEEWVMAIIRALNN
SMLSRHTIPLHICDTFTGTGCIALALSHGIANCTFTAIDVSTRAIKLVKENMLKNKVS
GGKLVQHNILSSKASDEYPSHIDILTGNPPYIRKRDFNRDVKTSVKLFEPRLALVGEL
ECYINLVNYWLPKTDSFFYEIGDVEQFNYVERRIKEDSYLSRIWSIGLKYDSNGKARV
VYGFKATPKGRILHQIFASFGTIRHLATALSGHKANCN"
gene complement(508776..510212)
/gene="GCD10"
/locus_tag="YNL062C"
/gene_synonym="TRM6"
/db_xref="GeneID:855663"
mRNA complement(508776..510212)
/gene="GCD10"
/locus_tag="YNL062C"
/gene_synonym="TRM6"
/product="Gcd10p"
/transcript_id="NM_001182900.3"
/db_xref="GI:398365150"
/db_xref="GeneID:855663"
CDS complement(508776..510212)
/gene="GCD10"
/locus_tag="YNL062C"
/gene_synonym="TRM6"
/note="Subunit of tRNA (1-methyladenosine)
methyltransferase with Gcd14p, required for the
modification of the adenine at position 58 in tRNAs,
especially tRNAi-Met; first identified as a negative
regulator of GCN4 expression"
/codon_start=1
/product="Gcd10p"
/protein_id="NP_014337.3"
/db_xref="GI:398365151"
/db_xref="SGD:S000005006"
/db_xref="GeneID:855663"
/translation="MNALTTIDFNQHVIVRLPSKNYKIVELKPNTSVSLGKFGAFEVN
DIIGYPFGLTFEIYYDGEEVSSDENRDSKPKNKIPIGKVRLLSQEIKDVNNDKDDGQS
EPPLSIKEKSVSLELSSIDSSATNQNLVNMGSKAQELTVEEIEKMKQESLSSKEIIDK
IIKSHKSFHNKTVYSQEKYVNRKKQKFAKYFTVEYLSSSNLLQFLIDKGDIQRVLDMS
QESMGMLLNLANIQSEGNYLCMDETGGLLVYFLLERMFGGDNESKSKGKVIVIHENEH
ANLDLLKFANYSEKFIKEHVHTISLLDFFEPPTLQEIQSRFTPLPKEEARALKGGKKN
SYYRKLRWYNTQWQILELTGEFLYDGLVMATTLHLPTLVPKLAEKIHGSRPIVCYGQF
KETLLELAHTLYSDLRFLAPSILETRCRPYQSIRGKLHPLMTMKGGGGYLMWCHRVIP
APEPVSENATAADSSEKLAEHGAKKQKI"
gene 510540..512396
/gene="NOP2"
/locus_tag="YNL061W"
/gene_synonym="YNA1"
/db_xref="GeneID:855664"
mRNA 510540..512396
/gene="NOP2"
/locus_tag="YNL061W"
/gene_synonym="YNA1"
/product="Nop2p"
/transcript_id="NM_001182899.3"
/db_xref="GI:398365156"
/db_xref="GeneID:855664"
CDS 510540..512396
/gene="NOP2"
/locus_tag="YNL061W"
/gene_synonym="YNA1"
/EC_number="2.1.1.-"
/note="Probable RNA m(5)C methyltransferase, essential for
processing and maturation of 27S pre-rRNA and large
ribosomal subunit biogenesis; localized to the nucleolus;
constituent of 66S pre-ribosomal particles"
/codon_start=1
/product="Nop2p"
/protein_id="NP_014338.3"
/db_xref="GI:398365157"
/db_xref="SGD:S000005005"
/db_xref="GeneID:855664"
/translation="MGSRRHKNKQAAPPTLEEFQARKEKKANRKLEKGKRPSTTQGDE
VSDRKKKKSKPFKKSRKEEEEVVEEDKDLPEVDLEELSKARKSLFDDEEDDDEAGLVD
EELKDEFDLEQEYDYDEDEDNDAHPIFSDDDDEADLEELNAQNMEALSKKLDEEEAEE
AEEAEMELVEAENMQPRADILPTEEQEEMMAQETPNLTSTRTRMIEIVKVLENFKTLG
AEGRSRGEYVDRLLKDICEYFGYTPFLAEKLFNLFSPAEAMEFFEANEIARPITIRTN
TLKTRRRDLAQTLVNRGVNLQPIGSWTKVGLQIFDSQVPIGATPEYLAGHYILQAASS
FLPVIALDPHENERILDMAAAPGGKTTYISAMMKNTGCVFANDANKSRTKSLIANIHR
LGCTNTIVCNYDAREFPKVIGGFDRILLDAPCSGTGVIGKDQSVKVSRTEKDFIQIPH
LQKQLLLSAIDSVDCNSKHGGVIVYSTCSVAVEEDEAVIDYALRKRPNVKLVDTGLAI
GKEAFTSYRGKKFHPSVKLARRYYPHTYNVDGFFVAKFQKIGPSSFDDNQASAKEKET
AARKEALEEGIIHSDFATFEDEEDDKYIEKSVKNNLLKKGVNPKAKRPSNEK"
gene complement(512668..514935)
/gene="ARP5"
/locus_tag="YNL059C"
/db_xref="GeneID:855665"
mRNA complement(512668..514935)
/gene="ARP5"
/locus_tag="YNL059C"
/product="Arp5p"
/transcript_id="NM_001182898.1"
/db_xref="GI:296147707"
/db_xref="GeneID:855665"
CDS complement(512668..514935)
/gene="ARP5"
/locus_tag="YNL059C"
/note="Nuclear actin-related protein involved in chromatin
remodeling, component of chromatin-remodeling enzyme
complexes"
/codon_start=1
/product="Arp5p"
/protein_id="NP_014339.1"
/db_xref="GI:6324269"
/db_xref="SGD:S000005004"
/db_xref="GeneID:855665"
/translation="MSSRDASLTPLKAVVIDDPPLRQTPEPFDEQSAYNPQSPIAIDF
GSSKLRAGFVNHATPTHIFPNALTKFRDRKLNKNFTFVGNDTLLDQAVRSQSRSPFDG
PFVTNWNLTEEILDYTFHHLGVVPDNGIPNPILLTERLATVQSQRTNWYQILFETYNV
PGVTFGIDSLFSFYNYNPSGNKTGLVISCGHEDTNVIPVVDGAGILTDAKRINWGGHQ
AVDYLNDLMALKYPYFPTKMSYLQYETMYKDYCYVSRNYDEDIEKILTLENLDTNDVV
VEAPFTEVLQPQKTEEELRIQAEKRKETGKRLQEQARLKRMEKLVQKQEEFEYFSKVR
DQLIDEPKKKVLSVLQNAGFDDERDFKKYLHSLEQSLKKAQMVEAEDDSHLDEMNEDK
TAQKFDLLDIADEDLNEDQIKEKRKQRFLKASQDARQKAKEEKERVAKEEEEKKLKEQ
QWRETDLNGWIKDKRLKLNKLIKRRKEKLKLRDEMKDRKSQVSQNRMKNLASLAEDNV
KQGAKRNRHQATIDNDPNDTFGANDEDWLIYTDITQNPEAFEEALEYEYKDIVELERL
LLEHDPNFTEEDTLEAQYDWRNSILHLFLRGPRPHDSENIHEQHQMHLNVERIRVPEV
IFQPTMGGQDQAGICELSETILLKKFGSQPGKLSQTSIDMVNNVLITGGNAKVPGLKE
RIVKEFTGFLPTGTNITVNMSSDPSLDAWKGMAALARNEEQYRKTVISKKEYEEYGPE
YIKEHKLGNTKYFED"
gene complement(515763..516713)
/locus_tag="YNL058C"
/db_xref="GeneID:855667"
mRNA complement(515763..516713)
/locus_tag="YNL058C"
/product="hypothetical protein"
/transcript_id="NM_001182897.1"
/db_xref="GI:296147708"
/db_xref="GeneID:855667"
CDS complement(515763..516713)
/locus_tag="YNL058C"
/note="hypothetical protein; green fluorescent protein
(GFP)-fusion protein localizes to the vacuole; YNL058C is
not an essential gene"
/codon_start=1
/product="hypothetical protein"
/protein_id="NP_014340.1"
/db_xref="GI:6324271"
/db_xref="SGD:S000005003"
/db_xref="GeneID:855667"
/translation="MVKKNFIPSVSLVRRDLPTLVTTTTSSTALSKPTSSVVSETSSK
SLPSLTSSAFSTSSGATSSSSLIVASITPPSTAGNPFILNAADKPNGTVYIAVGAVIG
AIFISILIWWLVSSYLSRRFTMTNSYANDSKNLYRGHHKHSSSLQSNPFDINDEKSYM
QDDWDSMSQLESSQYEDAASPFNPIQDPFTDNRRSLFISPTLQVSQYEKSHSRHQSKD
TNIFIDDPFLYVGTYLEEEEEEEEERKLNLNRPQRAASPERKEKKINSMEGYHKRNQS
SLGLIPVASATSNTSSPKKAHKRQAPSMFLDDVLNGREII"
gene 517249..517842
/gene="OCA2"
/locus_tag="YNL056W"
/db_xref="GeneID:855668"
mRNA 517249..517842
/gene="OCA2"
/locus_tag="YNL056W"
/product="Oca2p"
/transcript_id="NM_001182895.3"
/db_xref="GI:398365188"
/db_xref="GeneID:855668"
CDS 517249..517842
/gene="OCA2"
/locus_tag="YNL056W"
/note="Putative protein with similarity to predicted
tyrosine phosphatases Oca1p and Siw14p; green fluorescent
protein (GFP)-fusion protein localizes to the cytoplasm;
YNL056W is not an essential gene"
/codon_start=1
/product="Oca2p"
/protein_id="NP_014342.3"
/db_xref="GI:398365189"
/db_xref="SGD:S000005001"
/db_xref="GeneID:855668"
/translation="MKYIPPLNFSPVVSTDVSLYRSGYPMPLNYSFIKHQLHLKTIIY
IGDKDRPLEEYQSFLESEKIKYYHIFMDSSRDEGIQERMNQVLHLVLDVRNYPILVHS
NKGKHRVGVVVGIIRKLLQGWSTAGICQEYGLFSGGMKDGVDLEFITMFETNLKIPRN
VIPGFAKHCLYLNELEAAEGSDDESGSESILTAKQPI"
gene complement(517994..518845)
/gene="POR1"
/locus_tag="YNL055C"
/gene_synonym="OMP2"
/db_xref="GeneID:855669"
mRNA complement(517994..518845)
/gene="POR1"
/locus_tag="YNL055C"
/gene_synonym="OMP2"
/product="Por1p"
/transcript_id="NM_001182894.1"
/db_xref="GI:296147710"
/db_xref="GeneID:855669"
CDS complement(517994..518845)
/gene="POR1"
/locus_tag="YNL055C"
/gene_synonym="OMP2"
/note="Mitochondrial porin (voltage-dependent anion
channel); outer membrane protein required for the
maintenance of mitochondrial osmotic stability and
mitochondrial membrane permeability; phosphorylated;
protein abundance increases in response to DNA replication
stress"
/codon_start=1
/product="Por1p"
/protein_id="NP_014343.1"
/db_xref="GI:6324273"
/db_xref="SGD:S000005000"
/db_xref="GeneID:855669"
/translation="MSPPVYSDISRNINDLLNKDFYHATPAAFDVQTTTANGIKFSLK
AKQPVKDGPLSTNVEAKLNDKQTGLGLTQGWSNTNNLQTKLEFANLTPGLKNELITSL
TPGVAKSAVLNTTFTQPFFTARGAFDLCLKSPTFVGDLTMAHEGIVGGAEFGYDISAG
SISRYAMALSYFAKDYSLGATLNNEQITTVDFFQNVNAFLQVGAKATMNCKLPNSNVN
IEFATRYLPDASSQVKAKVSDSGIVTLAYKQLLRPGVTLGVGSSFDALKLSEPVHKLG
WSLSFDA"
gene complement(519099..519169)
/locus_tag="tD(GUC)N"
/db_xref="GeneID:855670"
tRNA complement(519099..519169)
/locus_tag="tD(GUC)N"
/product="tRNA-Asp"
/note="Aspartate tRNA (tRNA-Asp), predicted by tRNAscan-SE
analysis"
/db_xref="SGD:S000006544"
/db_xref="GeneID:855670"
mobile_element 519163..525062
/note="YNLWTy1-2; Ty1 element, LTR retrotransposon of the
Copia (Pseudoviridae) group; contains co-transcribed genes
TYA Gag and TYB Pol, encoding proteins involved in
structure and function of virus-like particles, flanked by
two direct repeats"
/mobile_element_type="retrotransposon:YNLWTy1-2"
/db_xref="SGD:S000007142"
LTR 519163..519496
/note="Ty1 LTR"
/db_xref="SGD:S000007136"
gene 519456..524706
/locus_tag="YNL054W-B"
/note="TyB Gag-Pol protein; proteolytically processed to
make the Gag, RT, PR, and IN proteins that are required
for retrotransposition"
/db_xref="GeneID:855672"
/db_xref="SGD:S000007385"
mRNA 519456..524706
/locus_tag="YNL054W-B"
/transcript_id="NM_001184413.2"
/db_xref="GI:452832457"
/db_xref="GeneID:855672"
/db_xref="SGD:S000007385"
gene 519456..520778
/locus_tag="YNL054W-A"
/db_xref="GeneID:855671"
CDS 519456..520778
/locus_tag="YNL054W-A"
/note="Retrotransposon TYA Gag gene co-transcribed with
TYB Pol; translated as TYA or TYA-TYB polyprotein; Gag is
a nucleocapsid protein that is the structural constituent
of virus-like particles (VLPs); similar to retroviral Gag"
/codon_start=1
/product="gag protein"
/protein_id="NP_058180.1"
/db_xref="GI:7839195"
/db_xref="SGD:S000007384"
/db_xref="GeneID:855671"
/translation="MESQQLSQHSPISHGSACASVTSKEVHTNQDPLDVSASKIQEYD
KASTKANSQQTTTPASSAVPENPHHASPQTAQSHSPQNGPYPQQCMMTQNQANPSDWS
FYGRPSMIPYTPYQMSPMYFPPGPHSQFPQYPSSVGTPLSTPSPESGNTFTDSSSADS
DMTSTKKYVRPPPMLTSPNDFLNWVKTYIKFLQNSNLGGIIPTVNGKPVRQITDDELT
FLYNTFQIFAPSQFLPTWVKDILSVDYTDIMKILSKSIEKMQSDTQEANDIVTLANLQ
YNGSTPADAFETKVTNIIDRLNNNGIHINNKVACQLIMRGLSGEYKFLRYTRHRHLNM
TVAELFLDIHAIYEEQQGSRNSKPNYRRNPSDEKNDSRSYTNTTKPKVIARNPQKTNN
SKSKTARAHNVSTSNNSPSTDNDSISKSTTEPIQLNNKHDLHLRPETY"
LTR 524729..525062
/note="Ty1 LTR"
/db_xref="SGD:S000007137"
gene 526086..529583
/gene="VAC7"
/locus_tag="YNL054W"
/db_xref="GeneID:855673"
mRNA 526086..529583
/gene="VAC7"
/locus_tag="YNL054W"
/product="Vac7p"
/transcript_id="NM_001182893.3"
/db_xref="GI:398365208"
/db_xref="GeneID:855673"
CDS 526086..529583
/gene="VAC7"
/locus_tag="YNL054W"
/note="Integral vacuolar membrane protein involved in
vacuole inheritance and morphology; activates Fab1p kinase
activity under basal conditions and also after
hyperosmotic shock"
/codon_start=1
/product="Vac7p"
/protein_id="NP_014344.3"
/db_xref="GI:398365209"
/db_xref="SGD:S000004999"
/db_xref="GeneID:855673"
/translation="MTEEDRKLTVETETVEAPVANNLLLSNNSNVVAPNPSIPSASTS
TSPLHREIVDDSVATANTTSNVVQHNLPTIDNNLMDSDATSHNQDHWHSDINRAGTSM
STSDIPTDLHLEHIGSVSSTNNNSNNALINHNPLSSHLSNPSSSLRNKKSSLLVASNP
AFASDVELSKKKPAVISNNMPTSNIALYQTARSANIHGPSSTSASKAFRKASAFSNNT
APSTSNNIGSNTPPAPLLPLPSLSQQNKPKIIERPTMHVTNSREILLGENLLDDTKAK
NAPANSTTHDNGPVANDGLRIPNHSNADDNENNNKMKKNKNINSGKNERNDDTSKICT
TSTKTAPSTAPLGSTDNTQALTASVSSSNADNHNNNKKKTSSNNNGNNSNSASNKTNA
DIKNSNADLSASTSNNNAINDDSHESNSEKPTKADFFAARLATAVGENEISDSEETFV
YESAANSTKNLIFPDSSSQQQQQQQQPPKQQQQQQNHGITSKISAPLLNNNKKLLSRL
KNSRHISTGAILNNTIATISTNPNLNSNVMQNNNNLMSGHNHLDELSSIKQEPPHQLQ
QQQPPMDVQSVDSYTSDNPDSNVIAKSPDKRSSLVSLSKVSPHLLSSTSSNGNTISCP
NVATNSQELEPNNDISTKKSLSNSTLRHSSANRNSNYGDNKRPLRTTVSKIFDSNPNG
APLRRYSGVPDHVNLEDYIEQPHNYPTMQNSVKKDEFYNSRNNKFPHGLNFYGDNNVI
EEENNGDSSNVNRPQHTNLQHEFIPEDNESDENDIHSMFYYNHKNDLETKPLISDYGE
DEDVDDYDRPNATFNSYYGSASNTHELPLHGRMPSRSNNDYYDFMVGNNTGNNNQLNE
YTPLRMKRGQRHLSRTNNSIMNGSIHMNGNDDVTHSNINNNDIVGYSPHNFYSRKSPF
VKVKNFLYLAFVISSLLMTGFILGFLLATNKELQDVDVVVMDNVISSSDELIFDITVS
AFNPGFFSISVSQVDLDIFAKSSYLKCDSNGDCTVMEQERKILQITTNLSLVEESANN
DISGGNIETVLLGTAKKLETPLKFQGGAFNRNYDVSVSSVKLLSPGSREAKHENDDDD
DDDGDDGDDENNTNERQYKSKPNARDDKEDDTKKWKLLIKHDYELIVRGSMKYEVPFF
NTQKSTAIQKDSMVHPGKK"
gene 529942..531411
/gene="MSG5"
/locus_tag="YNL053W"
/db_xref="GeneID:855674"
mRNA 529942..531411
/gene="MSG5"
/locus_tag="YNL053W"
/product="Msg5p"
/transcript_id="NM_001182892.3"
/db_xref="GI:398365218"
/db_xref="GeneID:855674"
CDS 529942..531411
/gene="MSG5"
/locus_tag="YNL053W"
/EC_number="3.1.3.48"
/note="Dual-specificity protein phosphatase; exists in 2
isoforms; required for maintenance of a low level of
signaling through the cell integrity pathway, adaptive
response to pheromone; regulates and is regulated by
Slt2p; dephosphorylates Fus3p"
/codon_start=1
/product="Msg5p"
/protein_id="NP_014345.3"
/db_xref="GI:398365219"
/db_xref="SGD:S000004998"
/db_xref="GeneID:855674"
/translation="MQFHSDKQHLDSKTDIDFKPNSPRSLQNRNTKNLSLDIAALHPL
MEFSSPSQDVPGSVKFPSPTPLNLFMKPKPIVLEKCPPKVSPRPTPPSLSMRRSEASI
YTLPTSLKNRTVSPSVYTKSSTVSSISKLSSSSPLSSFSEKPHLNRVHSLSVKTKDLK
LKGIRGRSQTISGLETSTPISSTREGTLDSTDVNRFSNQKNMQTTLIFPEEDSDLNID
MVHAEIYQRTVYLDGPLLVLPPNLYLYSEPKLEDILSFDLVINVAKEIPNLEFLIPPE
MAHKIKYYHIEWTHTSKIVKDLSRLTRIIHTAHSQGKKILVHCQCGVSRSASLIVAYI
MRYYGLSLNDAYNKLKGVAKDISPNMGLIFQLMEWGTMLSKNSPGEEGETVHMPEEDD
IGNNEVSSTTKSYSSASFRSFPMVTNLSSSPNDSSVNSSEVTPRTPATLTGARTALAT
ERGEDDEHCKSLSQPADSLEASVDNESISTAPEQMMFLP"
gene 531725..532186
/gene="COX5A"
/locus_tag="YNL052W"
/db_xref="GeneID:855675"
mRNA 531725..532186
/gene="COX5A"
/locus_tag="YNL052W"
/product="cytochrome c oxidase subunit Va"
/transcript_id="NM_001182891.1"
/db_xref="GI:296147714"
/db_xref="GeneID:855675"
CDS 531725..532186
/gene="COX5A"
/locus_tag="YNL052W"
/EC_number="1.9.3.1"
/note="Subunit Va of cytochrome c oxidase; cytochrome c
oxidase is the terminal member of the mitochondrial inner
membrane electron transport chain; Cox5Ap is predominantly
expressed during aerobic growth while its isoform Vb
(Cox5Bp) is expressed during anaerobic growth; COX5A has a
paralog, COX5B, that arose from the whole genome
duplication"
/codon_start=1
/product="cytochrome c oxidase subunit Va"
/protein_id="NP_014346.1"
/db_xref="GI:6324276"
/db_xref="SGD:S000004997"
/db_xref="GeneID:855675"
/translation="MLRNTFTRAGGLSRITSVRFAQTHALSNAAVMDLQSRWENMPST
EQQDIVSKLSERQKLPWAQLTEPEKQAVWYISYGEWGPRRPVLNKGDSSFIAKGVAAG
LLFSVGLFAVVRMAGGQDAKTMNKEWQLKSDEYLKSKNANPWGGYSQVQSK"
gene 532659..533870
/gene="COG5"
/locus_tag="YNL051W"
/gene_synonym="API4; COD4"
/db_xref="GeneID:855676"
mRNA 532659..533870
/gene="COG5"
/locus_tag="YNL051W"
/gene_synonym="API4; COD4"
/product="Cog5p"
/transcript_id="NM_001182890.1"
/db_xref="GI:296147715"
/db_xref="GeneID:855676"
CDS 532659..533870
/gene="COG5"
/locus_tag="YNL051W"
/gene_synonym="API4; COD4"
/note="Component of the conserved oligomeric Golgi complex
(Cog1p through Cog8p), a cytosolic tethering complex that
functions in protein trafficking to mediate fusion of
transport vesicles to Golgi compartments"
/codon_start=1
/product="Cog5p"
/protein_id="NP_014347.1"
/db_xref="GI:6324277"
/db_xref="SGD:S000004996"
/db_xref="GeneID:855676"
/translation="MTIAPMANDLEDFESLLEPDFDAKQFGNDLLKATNNNDTTILDL
NTPLKKLNYDLHEIDSRIDQLMNSNPLEIIELIYKNEHVNSTIVGELKPSLGYMNMSY
DRLKNQVLDPYERARKVQLALSKVYQTSFLLRGALLYIHLSNKLNALSKTAQLSTSTA
INLASLHYQLEITLEENKNLKSLRKIKQLDQDIVSPNKRELITFLSLQMCKECLNSIK
IKSNKEIISQLAYSLYLLSSQEFESAINKIVLSNVTMSSQILSKILNSIRMFPDAFNE
VVEKGYNIYILETLLQNIKTDNVTNSSRSIAANKSRLGNLLSEYTSMKSKAGSGTPRD
LFWSKVSSAFKKDFDISVNRGGPVGKSLLKNKDFIINTMKQSMKKSSDNSDYQSYLDV
MLNSVSISLNK"
gene complement(534079..534982)
/locus_tag="YNL050C"
/db_xref="GeneID:855677"
mRNA complement(join(534079..534874,534966..534982))
/locus_tag="YNL050C"
/product="hypothetical protein"
/transcript_id="NM_001182889.3"
/db_xref="GI:398365238"
/db_xref="GeneID:855677"
CDS complement(join(534079..534874,534966..534982))
/locus_tag="YNL050C"
/note="hypothetical protein; YNL050c is not an essential
gene"
/codon_start=1
/product="hypothetical protein"
/protein_id="NP_014348.3"
/db_xref="GI:398365239"
/db_xref="SGD:S000004995"
/db_xref="GeneID:855677"
/translation="MSEFKIVSRKDLYNEGEGLGEDYDSNSSSKNNSEHVEVLVPPTE
FEFVEVERTDSSLDLKESNNSAHEQKEEKQEEFEFPLFSFGVVEASTSPAQEEQGSST
QEKDTPQTEVSLMKISLKEPEEEIINQERPKDYYFASYSADQKLQFQQSSIDYDVIIQ
ESTKILEDDLRIRDKWPYCQGRIIDLYKHNARIELEQQKELKIKKRRPGQKQRAAKKL
ALERTKERDTKAREIKKQLKKKFHKRGGKKNKKKVPLNPLAKAGSTPKFRTE"
gene complement(535281..537911)
/gene="SFB2"
/locus_tag="YNL049C"
/gene_synonym="ISS1"
/db_xref="GeneID:855678"
mRNA complement(535281..537911)
/gene="SFB2"
/locus_tag="YNL049C"
/gene_synonym="ISS1"
/product="Sfb2p"
/transcript_id="NM_001182888.1"
/db_xref="GI:296147717"
/db_xref="GeneID:855678"
CDS complement(535281..537911)
/gene="SFB2"
/locus_tag="YNL049C"
/gene_synonym="ISS1"
/note="Component of the Sec23p-Sfb2p heterodimer of the
COPII vesicle coat, required for cargo selection during
vesicle formation in ER to Golgi transport; homologous to
Sec24p and Sfb3p"
/codon_start=1
/product="Sfb2p"
/protein_id="NP_014349.1"
/db_xref="GI:6324279"
/db_xref="SGD:S000004994"
/db_xref="GeneID:855678"
/translation="MSHHKKRVYPQAQVPYIASMPIVAEQQQSQQQIDQTAYAMGNLQ
LNNRANSFTQLAQNQQFPGSGKVVNQLYPVDLFTELPPPIRDLSLPPLPITISQDNIV
TPSEYSNVPYQYVRSTLKAVPKTNSLLKKTKLPFAIVIRPYLHLQDSDNQVPLNTDGV
IVRCRRCRSYMNPFVVFINQGRKWQCNICRFKNDVPFGFDQNLQGAPINRYERNEIKN
SVVDYLAPVEYSVREPPPSVYVFLLDVSQNAVKNGLLATSARTILENIEFLPNHDGRT
RIAIICVDHSLHYFYVPLDDDYEVSDEDDEESDGEEEDEDEEEEDVDNSETIQMFDIG
DLDEPFLPMPSDELVVPLKYCKNNLETLLKKIPEIFQDTHSSKFALGPALKAASNLIK
STGGKVEVISSTLPNTGIGKLKKRSEQGILNTPKESSQLLSCKDSFYKTFTIECNKLQ
ITVDMFLASEDYMDVATLSHLGRFSGGQTHFYPGFNATSLNDVTKFTRELSRHLSMDI
SMEAVMRVRCSTGLRATSFFGHFFNRSSDLCAFSTMPRDQSYLFGISIEDSLMAEYCY
LQVSTLLTLNTGERRIRVMTLALPTSESAREVFASADQLAITDFMTQNAVTKALNSSM
YSARDFITKSLEDILNAYKKEISMSNINSVTSLNLCANLRMLPLLMNGLSKHIALRPG
VVPSDYRASALNRLETEPLHYLIKSIYPTVYSLHDMPDEVGLPDFEGKTVLPEPINAT
ISLFERYGLYLIDNSAELFLWVGGDAVPELLIDVFNTDTISQIPVGKSELPLLNDSPF
NERLRRIIGRIRENNDTITFQSLYIIRGPSINEPANLNSEKDMASLRLWVLSTLVEDK
VLNCASYREYLQSMKTSINR"
gene 538173..539819
/gene="ALG11"
/locus_tag="YNL048W"
/db_xref="GeneID:855679"
mRNA 538173..539819
/gene="ALG11"
/locus_tag="YNL048W"
/product="alpha-1,2-mannosyltransferase ALG11"
/transcript_id="NM_001182887.1"
/db_xref="GI:296147718"
/db_xref="GeneID:855679"
CDS 538173..539819
/gene="ALG11"
/locus_tag="YNL048W"
/EC_number="2.4.1.-"
/note="Alpha-1,2-mannosyltransferase, catalyzes sequential
addition of the two terminal alpha 1,2-mannose residues to
the Man5GlcNAc2-PP-dolichol intermediate during
asparagine-linked glycosylation in the ER"
/codon_start=1
/product="alpha-1,2-mannosyltransferase ALG11"
/protein_id="NP_014350.1"
/db_xref="GI:6324280"
/db_xref="SGD:S000004993"
/db_xref="GeneID:855679"
/translation="MGSAWTNYNFEEVKSHFGFKKYVVSSLVLVYGLIKVLTWIFRQW
VYSSLNPFSKKSSLLNRAVASCGEKNVKVFGFFHPYCNAGGGGEKVLWKAVDITLRKD
AKNVIVIYSGDFVNGENVTPENILNNVKAKFDYDLDSDRIFFISLKLRYLVDSSTWKH
FTLIGQAIGSMILAFESIIQCPPDIWIDTMGYPFSYPIIARFLRRIPIVTYTHYPIMS
KDMLNKLFKMPKKGIKVYGKILYWKVFMLIYQSIGSKIDIVITNSTWTNNHIKQIWQS
NTCKIIYPPCSTEKLVDWKQKFGTAKGERLNQAIVLAQFRPEKRHKLIIESFATFLKN
LPDSVSPIKLIMAGSTRSKQDENYVKSLQDWSENVLKIPKHLISFEKNLPFDKIEILL
NKSTFGVNAMWNEHFGIAVVEYMASGLIPIVHASAGPLLDIVTPWDANGNIGKAPPQW
ELQKKYFAKLEDDGETTGFFFKEPSDPDYNTTKDPLRYPNLSDLFLQITKLDYDCLRV
MGARNQQYSLYKFSDLKFDKDWENFVLNPICKLLEEEERG"
gene complement(539911..541881)
/gene="SLM2"
/locus_tag="YNL047C"
/gene_synonym="LIT1"
/db_xref="GeneID:855680"
mRNA complement(539911..541881)
/gene="SLM2"
/locus_tag="YNL047C"
/gene_synonym="LIT1"
/product="Slm2p"
/transcript_id="NM_001182886.3"
/db_xref="GI:398365254"
/db_xref="GeneID:855680"
CDS complement(539911..541881)
/gene="SLM2"
/locus_tag="YNL047C"
/gene_synonym="LIT1"
/note="Phosphoinositide PI4,5P(2) binding protein, forms a
complex with Slm1p; acts downstream of Mss4p in a pathway
regulating actin cytoskeleton organization in response to
stress; phosphorylated by the TORC2 complex"
/codon_start=1
/product="Slm2p"
/protein_id="NP_014351.3"
/db_xref="GI:398365255"
/db_xref="SGD:S000004992"
/db_xref="GeneID:855680"
/translation="MSYQRNSARASLDLRSQYQQLEGRMRSEHFNPAYQQQQQKGQNI
PLSLPSSLAQRNPIPYPIDAVTSDPTIPAQLNVYDHDRQNSIVDAAAGTNTTHSLNSN
NIPSSQNNNINNNNINNVGSFTDPSMLTLPKMSLHSHQKQYDSNQNDPRSPLAILIPT
SAQPTDVLSARFSAWRNVIRAILVYLSETASIQDEIVRQQLRLSHAVQFPFFSIENQY
QPVSNEDKSMQKFFLPLGSGSVQDLPTMLTKYHDNLASLASKSSKELTSEIIPRLEDL
RRDLLVKIKEIKALQSDFKNSCNKELQQTKHLMKLFNESLKECKLGTPKSDPFLIKLQ
LEKQIKRQLVEENYLHEAFDNLQNSGAQLESVIVMEIQNGLTSYARILGKEAQVVFDS
VISKLDSTILNKNTNLEWDSFILRNISNFVPPNLPMRRFKEISYSNQNDPFTFEVKSG
FLEKRSKFLKSYSRGFYVLTPSFLHEFKTPDKHKFSTPLMSIPLVECTVTEHSKKTKS
NSEQGKNKFILRTNSNGLIHRGHNWVFKVDSYDDMIEWFGNIKALSSLPNYDDKCKYV
SKVAKLSKEKAKSNENTTESVTPQVTNEQHTRYDDVSSSNFPLNSIPKLDNLTITNTT
SSIPETNDSQIQNRVPEFYIENVDSPRKSNQL"
gene 542304..542822
/locus_tag="YNL046W"
/db_xref="GeneID:855681"
mRNA 542304..542822
/locus_tag="YNL046W"
/product="hypothetical protein"
/transcript_id="NM_001182885.3"
/db_xref="GI:398365262"
/db_xref="GeneID:855681"
CDS 542304..542822
/locus_tag="YNL046W"
/note="hypothetical protein; expression depends on Swi5p;
GFP-fusion protein localizes to the endoplasmic reticulum;
deletion confers sensitivity to
4-(N-(S-glutathionylacetyl)amino) phenylarsenoxide (GSAO)"
/codon_start=1
/product="hypothetical protein"
/protein_id="NP_014352.3"
/db_xref="GI:398365263"
/db_xref="SGD:S000004991"
/db_xref="GeneID:855681"
/translation="MEHVSKRSIGQFFKRKTSTVDGSKSQKCGTTNQLRKLLHKRRVQ
KQAVPVESQYRIPGDFRDNQSVRVKNSMYNSSPSVTPSTHHINERYVRYDINTRPLVV
VLAISIVFFGCLLVLKDIIIQSSENILSVSKWKIIGASFMGTPYTGLLTGLVGPLLSP
FSAVSSWLSFIF"
gene 542963..544978
/gene="LAP2"
/locus_tag="YNL045W"
/db_xref="GeneID:855682"
mRNA 542963..544978
/gene="LAP2"
/locus_tag="YNL045W"
/product="Lap2p"
/transcript_id="NM_001182884.1"
/db_xref="GI:296147721"
/db_xref="GeneID:855682"
CDS 542963..544978
/gene="LAP2"
/locus_tag="YNL045W"
/EC_number="3.3.2.6"
/note="Leucyl aminopeptidase yscIV (leukotriene A4
hydrolase) with epoxide hydrolase activity, metalloenzyme
containing one zinc atom; green fluorescent protein
(GFP)-fusion protein localizes to the cytoplasm and
nucleus"
/codon_start=1
/product="Lap2p"
/protein_id="NP_014353.1"
/db_xref="GI:6324283"
/db_xref="SGD:S000004990"
/db_xref="GeneID:855682"
/translation="MFLLPFVIRHSSSIYLPTLRFRGLLTVISRNIHISTPHKMLPLS
IEQRRPSRSPEYDQSTLSNYKDFAVLHTDLNLSVSFEKSAISGSVTFQLKKLHEGKNK
SDELHLDTSYLDVQEVHIDGSKADFQIEQRKEPLGSRLVINNASCNDNFTLNIQFRTT
DKCTALQWLNSKQTKGGKPYVFSQLEAIHARSLFPCFDTPSVKSTFTASIESPLPVVF
SGIRIEDTSKDTNIYRFEQKVPIPAYLIGIASGDLSSAPIGPRSTVYTEPFRLKDCQW
EFENDVEKFIQTAEKIIFEYEWGTYDILVNVDSYPYGGMESPNMTFATPTLIAHDRSN
IDVIAHELAHSWSGNLVTNCSWNHFWLNEGWTVYLERRIIGAIHGEPTRHFSALIGWS
DLQNSIDSMKDPERFSTLVQNLNDNTDPDDAFSTVPYEKGFNLLFHLETILGGKAEFD
PFIRHYFKKFAKKSLDTFQFLDTLYEFYPEKKEILDSVDWETWLYKPGMPPRPHFITA
LADNVYQLADKWVEMAQHLKTTEDFRSEFNAIDIKDFNSNQLVLFLETLTQNGHSNKK
PKDFDWAKFPVASRALLDIYQDNIVKSQNAEVVFKMFKFQIFAKLQEEYKHLADWLGT
VGRMKFVRPGYRLLNSVDRRLALATFDKFKDTYHPICKALVKQDLGL"
gene 545268..545877
/gene="YIP3"
/locus_tag="YNL044W"
/db_xref="GeneID:855683"
mRNA join(545268..545291,545371..545877)
/gene="YIP3"
/locus_tag="YNL044W"
/product="Yip3p"
/transcript_id="NM_001182883.1"
/db_xref="GI:296147722"
/db_xref="GeneID:855683"
CDS join(545268..545291,545371..545877)
/gene="YIP3"
/locus_tag="YNL044W"
/note="Protein localized to COPII vesicles, proposed to be
involved in ER to Golgi transport; interacts with members
of the Rab GTPase family and Yip1p; also interacts with
Rtn1p"
/codon_start=1
/product="Yip3p"
/protein_id="NP_014354.2"
/db_xref="GI:6681850"
/db_xref="SGD:S000004989"
/db_xref="GeneID:855683"
/translation="MNQLGALAQVSRFTQNFSMENIKSEFQSLQSKLATLRTPQEFFN
FKKISKPQNFGEVQSRVAYNLKYFSSNYGLIIGCLSIYTLLTNLLLLFVIVLVVAGIV
GINKLKGEELVTPFGSFKTNQLYTGLVCVAVPIGFLASPISTLLWLIGASAVSVFGHA
SLMEKPIETVFDEETV"
rep_origin 545971..546205
/note="ARS1421;
Autonomously Replicating Sequence"
/db_xref="SGD:S000118389"
LTR 546423..546714
/note="Ty3 LTR"
/db_xref="SGD:S000007138"
LTR 546738..547077
/note="Ty3 LTR"
/db_xref="SGD:S000007139"
gene 547094..547196
/locus_tag="tP(UGG)N1"
/db_xref="GeneID:855685"
tRNA join(547094..547129,547161..547196)
/locus_tag="tP(UGG)N1"
/product="tRNA-Pro"
/note="Proline tRNA (tRNA-Pro), predicted by tRNAscan-SE
analysis; target of K. lactis zymocin"
/db_xref="SGD:S000006685"
/db_xref="GeneID:855685"
gene 547113..547370
/locus_tag="YNL042W-B"
/db_xref="GeneID:1466515"
mRNA 547113..547370
/locus_tag="YNL042W-B"
/product="hypothetical protein"
/transcript_id="NM_001184662.3"
/db_xref="GI:398365282"
/db_xref="GeneID:1466515"
CDS 547113..547370
/locus_tag="YNL042W-B"
/codon_start=1
/product="hypothetical protein"
/protein_id="NP_878157.3"
/db_xref="GI:398365283"
/db_xref="SGD:S000028850"
/db_xref="GeneID:1466515"
/translation="MILALGDFLPKQEDKACERPWVQFPARPVIFFHHQGGIFLFSIN
QPNLSCFSKLKEVNSLYVRVATYICQKNESRFRTNRLKGDQ"
gene 548100..549290
/gene="BOP3"
/locus_tag="YNL042W"
/db_xref="GeneID:855686"
mRNA 548100..549290
/gene="BOP3"
/locus_tag="YNL042W"
/product="Bop3p"
/transcript_id="NM_001182881.1"
/db_xref="GI:296147724"
/db_xref="GeneID:855686"
CDS 548100..549290
/gene="BOP3"
/locus_tag="YNL042W"
/note="hypothetical protein, potential Cdc28p substrate;
overproduction confers resistance to methylmercury"
/codon_start=1
/product="Bop3p"
/protein_id="NP_014356.1"
/db_xref="GI:6324286"
/db_xref="SGD:S000004987"
/db_xref="GeneID:855686"
/translation="MSTFNSYSQPKESNDNSHNNVNKSKSLLDIIFGTNVSEWAFSEN
ALMKAMDLKIEQEKTKQQYYKLENLNRSIELFKLASSSGLPINQIHKLFNTDHGVPAS
SPMKAGGNQPHNNTEGTQSSENLPRLNGSMKSLKPLNMNTVSPTPMSRQPSPYKFPAS
SSTGGISHSTVTNVQRRANSPARIGASAVAALNDNISIKEEDVARRIPSGTKSQESPL
NKKPTSLHSRNLSLPIGKFTNPNIPSTMTSILSFNRDQQQPLSQPLPPPPQQQQDLHT
HNLHTIPRKPGMVQKKHRRARSTSSFGVIDLSIIDEAKEKQVQRSPSPIHSNVSVALT
SHDKPIESNMKEQPNMLQSVREGRQVHDDLDDRTCSESSSRNESPVRTITKDNSVGKI
LNST"
gene complement(549468..551987)
/gene="COG6"
/locus_tag="YNL041C"
/gene_synonym="COD2; SEC37"
/db_xref="GeneID:855687"
mRNA complement(549468..551987)
/gene="COG6"
/locus_tag="YNL041C"
/gene_synonym="COD2; SEC37"
/product="Cog6p"
/transcript_id="NM_001182880.1"
/db_xref="GI:296147725"
/db_xref="GeneID:855687"
CDS complement(549468..551987)
/gene="COG6"
/locus_tag="YNL041C"
/gene_synonym="COD2; SEC37"
/note="Component of the conserved oligomeric Golgi complex
(Cog1p through Cog8p), a cytosolic tethering complex that
functions in protein trafficking to mediate fusion of
transport vesicles to Golgi compartments"
/codon_start=1
/product="Cog6p"
/protein_id="NP_014357.1"
/db_xref="GI:6324287"
/db_xref="SGD:S000004986"
/db_xref="GeneID:855687"
/translation="MDFVVDYQTYAMADTATPELPEPEPRLNLTSDAQSQPTGKLDLQ
FKLPDLQRYSNNNATLPVDNDGAGSKDLHKKMTHYAMSSIDKIQLSNPSKQLGQNSQD
EKLSQQESQNFTNYEPKNLDLSKLVSPSSGSNKNTTNLVLSNKLSKILNNYTLINYQA
TVQLRKSLKVLEENKERLSLDEQKLMNPEYVGTLARRALRTDLESQLLKEHITVLEEF
KPIIRRIKRLSSSVEKIQRTSEKLLSNETNEVPTNNVVLQEIDQYRLKAEQLKLKKKI
LLSIRDRFTLNQVEDDVITNGTIDNIFFEVVKKVINIKDESSFLLTLPNLNAGNALIM
GVNEILEKTNKKIFNYLIDFLYSFESSSNLLNDHGTTEQESLNIFRKSLVFLSSDLEL
FNELLKRVTTLRSKSILDEFLSQFDMNSTTSKPIILSAHDPIRYIGDVLASVHSIIAN
EADFVKSLFDFQDEDLKDTPISILQQNKTFLKGIDNKLLNDIIQSLSNSCRIRIEQIV
RFEENPIINFEIVRLLKLYRVMFERKGIQDDSSIINNLKSLEDISKNRIIGYYEDYMK
QTVMAETKNSSDDLLPPEWLSEYMNKLVELFEIYEKTHAAEDEESEDNKLLSSKNLQT
IVEQPIKDVLLKQLQTSFPLAKKNEKEKASLLTIEINCFDLIKSRLQPFEGLFAQDDD
SRKITIWVCDKLKEYTKQMLTLQIKFLFENTGLDLYSNLVNMIFPVDSVKDELDYDMY
LALRDNSLMELDMVRKNVHDKLNYYLPQALTDVQGNLLFKLTSPMIADEICDECFKKL
SLFYNIFRKLLIHLYPNKKDQVFEILNFSTDEFDMLIGIDH"
gene 553380..554750
/locus_tag="YNL040W"
/db_xref="GeneID:855688"
mRNA 553380..554750
/locus_tag="YNL040W"
/product="putative alanine--tRNA ligase"
/transcript_id="NM_001182879.3"
/db_xref="GI:398365300"
/db_xref="GeneID:855688"
CDS 553380..554750
/locus_tag="YNL040W"
/note="hypothetical protein with strong similarity to
alanyl-tRNA synthases from Eubacteria; green fluorescent
protein (GFP)-fusion protein localizes to the cytoplasm;
YNL040W is not an essential gene"
/codon_start=1
/product="putative alanine--tRNA ligase"
/protein_id="NP_014358.3"
/db_xref="GI:398365301"
/db_xref="SGD:S000004985"
/db_xref="GeneID:855688"
/translation="MPTPMTPVKVGALACQRNSFLFDGFKTLVVSCEPTKNKKGEIEG
YEIELQDTILFPEGGGQPSDSGFLKIVEGNRNSSKIEKILVSHVSRFGLHAKHHVNDY
IEPGTTVEVAVDEQKRMDYMQQHTGQHLLSAILERNYKVDTVSWSMGGIITKKKPVLE
PSDYFNYIELNRKLTLDEITNVSDEINQLIINFPQEIIVEERIGEETVDEVSTSKIPD
DYDLSKGVLRTIHIGDIDSNPCCGTHLKCTSQIGSILILSNQSAVRGSNSRLYFMCGK
RVSLYAKSVNKILLDSKNLLSCSETQISEKITRQTKQIQQLNKREQYWIKRLARTASE
ELMNTLKASGKKRAYFMEEEYGTLELLLQIHKEVSNFLKDDTEGYEIILCGYERQTNT
GSLLILSESGEKIANLAANLGSILQNLKGGGGKKGGKWQGKITSISNAEFAALSDYLS
HDFASC"
gene 555048..556832
/gene="BDP1"
/locus_tag="YNL039W"
/gene_synonym="TFC5; TFC7"
/db_xref="GeneID:855689"
mRNA 555048..556832
/gene="BDP1"
/locus_tag="YNL039W"
/gene_synonym="TFC5; TFC7"
/product="Bdp1p"
/transcript_id="NM_001182878.3"
/db_xref="GI:398365308"
/db_xref="GeneID:855689"
CDS 555048..556832
/gene="BDP1"
/locus_tag="YNL039W"
/gene_synonym="TFC5; TFC7"
/note="Essential subunit of RNA polymerase III
transcription factor (TFIIIB), which is involved in
transcription of genes encoding tRNAs, 5S rRNA, U6 snRNA,
and other small RNAs"
/codon_start=1
/product="Bdp1p"
/protein_id="NP_014359.3"
/db_xref="GI:398365309"
/db_xref="SGD:S000004984"
/db_xref="GeneID:855689"
/translation="MSSIVNKSGTRFAPKVRQRRAATGGTPTPKPRTPQLFIPESKEI
EEDNSDNDKGVDENETAIVEKPSLVGERSLEGFTLTGTNGHDNEIGDEGPIDASTQNP
KADVIEDNVTLKPAPLQTHRDQKVPRSSRLASLSKDNESRPSFKPSFLDSSSNSNGTA
RRLSTISNKLPKKIRLGSITENDMNLKTFKRHRVLGKPSSAKKPAGAHRISIVSKISP
PTAMTDSLDRNEFSSETSTSREADENENYVISKVKDIPKKVRDGESAKYFIDEENFTM
AELCKPNFPIGQISENFEKSKMAKKAKLEKRRHLRELRMRARQEFKPLHSLTKEEQEE
EEEKRKEERDKLLNADIPESDRKAHTAIQLKLNPDGTMAIDEETMVVDRHKNASIENE
YKEKVDENPFANLYNYGSYGRGSYTDPWTVEEMIKFYKALSMWGTDFNLISQLYPYRS
RKQVKAKFVNEEKKRPILIELALRSKLPPNFDEYCCEIKKNIGTVADFNEKLIELQNE
HKHHMKEIEEAKNTAKEEDQTAQRLNDANLNKKGSGGIMTNDLKVYRKTEVVLGTIDD
LKRKKLKERNNDDNEDNEGSEEEPEIDQ"
gene 557020..557783
/gene="GPI15"
/locus_tag="YNL038W"
/db_xref="GeneID:855690"
mRNA join(557020..557610,557685..557783)
/gene="GPI15"
/locus_tag="YNL038W"
/product="Gpi15p"
/transcript_id="NM_001182877.1"
/db_xref="GI:296147728"
/db_xref="GeneID:855690"
CDS join(557020..557610,557685..557783)
/gene="GPI15"
/locus_tag="YNL038W"
/EC_number="2.4.1.198"
/note="Protein involved in the synthesis of
N-acetylglucosaminyl phosphatidylinositol (GlcNAc-PI), the
first intermediate in the synthesis of
glycosylphosphatidylinositol (GPI) anchors; homologous to
the human PIG-H protein"
/codon_start=1
/product="Gpi15p"
/protein_id="NP_014360.2"
/db_xref="GI:37362689"
/db_xref="SGD:S000004983"
/db_xref="GeneID:855690"
/translation="MISKEYEFGKTSILNRKKYTLVIDEDKNGNFIRFTVLPVSNRKF
KKVKQNGRVEINMGIQYHQIVLILLLNILFYVICLRSRFLEHINRTFEVTIARSFQIL
IIMGLFALGTIILVRGPSVETVTIFKESGLQLSRVKGMVIFPQQWNRKFFEQVEFISN
ERIIDVVINEGFCRGFRVIFYLAAIVRKSSTLKLLFPSNLPSIDDQRLIYNISRKYLS
KQEKPLSRPKD"
gene complement(557920..559002)
/gene="IDH1"
/locus_tag="YNL037C"
/db_xref="GeneID:855691"
mRNA complement(557920..559002)
/gene="IDH1"
/locus_tag="YNL037C"
/product="isocitrate dehydrogenase (NAD(+)) IDH1"
/transcript_id="NM_001182876.1"
/db_xref="GI:296147729"
/db_xref="GeneID:855691"
CDS complement(557920..559002)
/gene="IDH1"
/locus_tag="YNL037C"
/EC_number="1.1.1.41"
/note="Subunit of mitochondrial NAD(+)-dependent
isocitrate dehydrogenase, which catalyzes the oxidation of
isocitrate to alpha-ketoglutarate in the TCA cycle"
/codon_start=1
/product="isocitrate dehydrogenase (NAD(+)) IDH1"
/protein_id="NP_014361.1"
/db_xref="GI:6324291"
/db_xref="SGD:S000004982"
/db_xref="GeneID:855691"
/translation="MLNRTIAKRTLATAAQAERTLPKKYGGRFTVTLIPGDGVGKEIT
DSVRTIFEAENIPIDWETINIKQTDHKEGVYEAVESLKRNKIGLKGLWHTPADQTGHG
SLNVALRKQLDIYANVALFKSLKGVKTRIPDIDLIVIRENTEGEFSGLEHESVPGVVE
SLKVMTRPKTERIARFAFDFAKKYNRKSVTAVHKANIMKLGDGLFRNIITEIGQKEYP
DIDVSSIIVDNASMQAVAKPHQFDVLVTPSMYGTILGNIGAALIGGPGLVAGANFGRD
YAVFEPGSRHVGLDIKGQNVANPTAMILSSTLMLNHLGLNEYATRISKAVHETIAEGK
HTTRDIGGSSSTTDFTNEIINKLSTM"
gene 559814..560479
/gene="NCE103"
/locus_tag="YNL036W"
/gene_synonym="NCE3"
/db_xref="GeneID:855692"
mRNA 559814..560479
/gene="NCE103"
/locus_tag="YNL036W"
/gene_synonym="NCE3"
/product="carbonate dehydratase NCE103"
/transcript_id="NM_001182875.3"
/db_xref="GI:398365326"
/db_xref="GeneID:855692"
CDS 559814..560479
/gene="NCE103"
/locus_tag="YNL036W"
/gene_synonym="NCE3"
/note="Carbonic anhydrase; metalloenzyme that catalyzes
CO2 hydration to bicarbonate, which is an important
metabolic substrate, and protons; not expressed under
conditions of high CO2, such as inside a growing colony,
but transcription is induced in response to low CO2
levels, such as on the colony surface in ambient air;
poorly transcribed under aerobic conditions and at an
undetectable level under anaerobic conditions; abundance
increases in response to DNA replication stress"
/codon_start=1
/product="carbonate dehydratase NCE103"
/protein_id="NP_014362.3"
/db_xref="GI:398365327"
/db_xref="SGD:S000004981"
/db_xref="GeneID:855692"
/translation="MSATESSSIFTLSHNSNLQDILAANAKWASQMNNIQPTLFPDHN
AKGQSPHTLFIGCSDSRYNENCLGVLPGEVFTWKNVANICHSEDLTLKATLEFAIICL
KVNKVIICGHTDCGGIKTCLTNQREALPKVNCSHLYKYLDDIDTMYHEESQNLIHLKT
QREKSHYLSHCNVKRQFNRIIENPTVQTAVQNGELQVYGLLYNVEDGLLQTVSTYTKV
TPK"
gene complement(560693..560765)
/locus_tag="tT(AGU)N2"
/db_xref="GeneID:855693"
tRNA complement(560693..560765)
/locus_tag="tT(AGU)N2"
/product="tRNA-Thr"
/note="Threonine tRNA (tRNA-Thr), predicted by tRNAscan-SE
analysis"
/db_xref="SGD:S000006745"
/db_xref="GeneID:855693"
rep_origin 561111..561388
/note="ARS1422;
Autonomously Replicating Sequence"
/db_xref="SGD:S000118390"
LTR 561607..561977
/note="Ty4 LTR"
/db_xref="SGD:S000007141"
LTR complement(562033..562364)
/note="Ty2 LTR"
/db_xref="SGD:S000007131"
mobile_element complement(562364..567660)
/note="YNLCTy2-1; Ty2 element, LTR retrotransposon of the
Copia (Pseudoviridae) group; contains genes TYA Gag and
TYB Pol, encoding proteins involved in structure and
function of virus-like particles, flanked by two direct
repeats; mutated in S288C"
/mobile_element_type="retrotransposon:YNLCTy2-1"
/db_xref="SGD:S000007135"
LTR complement(567660..567992)
/note="Ty2 LTR"
/db_xref="SGD:S000007132"
gene 568115..568217
/locus_tag="tP(UGG)N2"
/db_xref="GeneID:855694"
tRNA join(568115..568150,568182..568217)
/locus_tag="tP(UGG)N2"
/product="tRNA-Pro"
/note="Proline tRNA (tRNA-Pro), predicted by tRNAscan-SE
analysis; target of K. lactis zymocin"
/db_xref="SGD:S000006686"
/db_xref="GeneID:855694"
rep_origin 568219..568524
/note="ARS1423;
Putative replication origin, identified in multiple array
studies, not yet confirmed by plasmid-based assay"
/db_xref="SGD:S000130143"
gene complement(568522..569691)
/locus_tag="YNL035C"
/db_xref="GeneID:855695"
mRNA complement(568522..569691)
/locus_tag="YNL035C"
/product="hypothetical protein"
/transcript_id="NM_001182874.1"
/db_xref="GI:296147731"
/db_xref="GeneID:855695"
CDS complement(568522..569691)
/locus_tag="YNL035C"
/note="hypothetical protein; has similarity to proteins
containing WD-40 domains; green fluorescent protein
(GFP)-fusion protein localizes to the nucleus; YNL035C is
not an essential gene; protein abundance increases in
response to DNA replication stress"
/codon_start=1
/product="hypothetical protein"
/protein_id="NP_014363.1"
/db_xref="GI:6324293"
/db_xref="SGD:S000004980"
/db_xref="GeneID:855695"
/translation="MASYSLVESNSFGSENWCLKLQPSYKHGLLTGLSNGEIRLLDWS
TGKSVQKIKASETAINDMKVIGSDFSAGHLVSSASIDAVKVFDIRTNDRIAQIQNEAN
SPFISLDSRHGLLACGTELQGIDAAVYIYDIRKWDTPLRSLIDSHHDDVTCIKFHPSD
VNILLSGSTDGYTNIYDLKQDEEEDALHQVINYASIHSCGWLSPKRIFTLSHMETFAI
HELNDKSDELKEPQPLDFGDVREIWNCDYVVDIYPGLIATGKTQENCGELCLLPFKDE
KVDTENGIVIPHAHGDEVVRDIFIPAQHSNMLYSCGEDGCVKIWENKQGPLDIPENFW
DYSKKMNVLGDDDREGSINLDEPLIIQKESVSTRPRKEKHKKAKKHSMKSRFKPY"
gene complement(569867..569940)
/locus_tag="tI(AAU)N1"
/db_xref="GeneID:855696"
tRNA complement(569867..569940)
/locus_tag="tI(AAU)N1"
/product="tRNA-Ile"
/note="Isoleucine tRNA (tRNA-Ile), predicted by
tRNAscan-SE analysis"
/db_xref="SGD:S000006609"
/db_xref="GeneID:855696"
gene 570477..572315
/locus_tag="YNL034W"
/db_xref="GeneID:855697"
mRNA 570477..572315
/locus_tag="YNL034W"
/product="hypothetical protein"
/transcript_id="NM_001182873.1"
/db_xref="GI:296147732"
/db_xref="GeneID:855697"
CDS 570477..572315
/locus_tag="YNL034W"
/note="hypothetical protein; YNL034W is not an essential
gene"
/codon_start=1
/product="hypothetical protein"
/protein_id="NP_014364.1"
/db_xref="GI:6324294"
/db_xref="SGD:S000004979"
/db_xref="GeneID:855697"
/translation="MSTSFQEFKAFCNKVGLDFQWLNLQSSKSVPESGSSEGFSAVSD
TVQENIRPATEPLNVNQSKDPVSNFFYDVKNAPLWNVYKRNHSGHSSTEACSGVSSGQ
ASKNIPEAMVKETVLSNHDNVTIINELLPTSSAMHQEESTAMTTSYLLSHSVNDSCNV
MLSSSSHNRAMLPPSLVQRNNATTSPTTDSASENNESVPSLTSSVSTSSSVYSSWNPP
HSPHISSFPDGNFASLNAEVTCFDFRRTKDSRTKETNESIIPTEIYCPINSTDHHKHY
PSQKSKQDACAPAPRNQNISCSVGSAAEFSQSNHTLTTVVPSYMQQYLDRPQNWFESK
MGKYCPLFLRSTKNIDYDSLEFKFERKMIAVQYLLLDEQSEPRRYYNPSNKSIPFWKR
PFNFDTMPSYDQLMEEAECRFYSYQYKYEGFQRIEPYSIFCPWKNTQREIDLVLDHIH
FSLDVGEKKSLNRKGNITLDTLDSKVDPNIQIKPYQIFPSNNLVYEGLPHPAEQSLIL
SPGTSLIERAFQALIDICKESIPPSNDCTTRNHNSAPQLTVPEPSKPCRLLLVRESRT
ATELETNKKLWLHSQRRNIEVTVPMHPSEHGTKSRLRKWLSTFVHQ"
gene 572999..573853
/locus_tag="YNL033W"
/db_xref="GeneID:855698"
mRNA 572999..573853
/locus_tag="YNL033W"
/product="hypothetical protein"
/transcript_id="NM_001182872.3"
/db_xref="GI:398365334"
/db_xref="GeneID:855698"
CDS 572999..573853
/locus_tag="YNL033W"
/codon_start=1
/product="hypothetical protein"
/protein_id="NP_014365.3"
/db_xref="GI:398365335"
/db_xref="SGD:S000004978"
/db_xref="GeneID:855698"
/translation="MLYSRESRTTVLFLALVTSLTVLCHSVDVTTVFTTSTITEITTV
TAAPQPQNKAETALNTATNIIQTMQFLFNCAPFKWKGPLKITSCALNFIVLLLTAWGY
LLKYLQENKLNSDADMEKMVGLGFGEMVGRIFGKGVGKAFTKMDITQKLVYPFEGSNR
QKCLLMTVGENSIVPFHDLFTEICFDQYTLDSLSHHNHGSISILDAGSVSALGFADIS
SKMPSVSELYTLFGDYTIEVLGGITKLASTLNREDWQGERNGFAVLSRDRPNQTLLSV
HMYSSSLL"
gene 574506..575351
/gene="SIW14"
/locus_tag="YNL032W"
/gene_synonym="OCA3"
/db_xref="GeneID:855699"
mRNA 574506..575351
/gene="SIW14"
/locus_tag="YNL032W"
/gene_synonym="OCA3"
/product="Siw14p"
/transcript_id="NM_001182871.3"
/db_xref="GI:398365340"
/db_xref="GeneID:855699"
CDS 574506..575351
/gene="SIW14"
/locus_tag="YNL032W"
/gene_synonym="OCA3"
/EC_number="3.1.3.48"
/note="Tyrosine phosphatase that plays a role in actin
filament organization and endocytosis; localized to the
cytoplasm"
/codon_start=1
/product="Siw14p"
/protein_id="NP_014366.3"
/db_xref="GI:398365341"
/db_xref="SGD:S000004977"
/db_xref="GeneID:855699"
/translation="MGLYQAKNDEGSDPKSSSKIDDLIENEAEIIRLIKEDGKLLIDN
GDGRDIHNIIQEDKLLSVEFNEVLKRFHGEEKSDIPRKEFDEDEDDGYDSNEHHQKTI
EVMNTLNHVINKEVIPPENFSHVVGEIYRSSFPRQENFSFLHERLKLKSILVLIPEEY
PQENLNFLKLTGIKLYQVGMSGNKEPFVNIPSHLLTKALEIVLNPANQPILIHCNRGK
HRTGCLIGCIRKLQNWSLTMIFDEYRRFAFPKARALDQQFIEMYDDDEIKRIASKNNW
LPLQW"
gene complement(575640..576050)
/gene="HHT2"
/locus_tag="YNL031C"
/db_xref="GeneID:855700"
mRNA complement(575640..576050)
/gene="HHT2"
/locus_tag="YNL031C"
/product="Hht2p"
/transcript_id="NM_001182870.1"
/db_xref="GI:296147735"
/db_xref="GeneID:855700"
CDS complement(575640..576050)
/gene="HHT2"
/locus_tag="YNL031C"
/note="Histone H3, core histone protein required for
chromatin assembly, part of heterochromatin-mediated
telomeric and HM silencing; one of two identical histone
H3 proteins (see HHT1); regulated by acetylation,
methylation, and phosphorylation"
/codon_start=1
/product="Hht2p"
/protein_id="NP_014367.1"
/db_xref="GI:6324297"
/db_xref="SGD:S000004976"
/db_xref="GeneID:855700"
/translation="MARTKQTARKSTGGKAPRKQLASKAARKSAPSTGGVKKPHRYKP
GTVALREIRRFQKSTELLIRKLPFQRLVREIAQDFKTDLRFQSSAIGALQESVEAYLV
SLFEDTNLAAIHAKRVTIQKKDIKLARRLRGERS"
gene 576727..577038
/gene="HHF2"
/locus_tag="YNL030W"
/db_xref="GeneID:855701"
mRNA 576727..577038
/gene="HHF2"
/locus_tag="YNL030W"
/product="Hhf2p"
/transcript_id="NM_001182869.1"
/db_xref="GI:296147736"
/db_xref="GeneID:855701"
CDS 576727..577038
/gene="HHF2"
/locus_tag="YNL030W"
/note="Histone H4, core histone protein required for
chromatin assembly and chromosome function; one of two
identical histone proteins (see also HHF1); contributes to
telomeric silencing; N-terminal domain involved in
maintaining genomic integrity"
/codon_start=1
/product="Hhf2p"
/protein_id="NP_014368.1"
/db_xref="GI:6324298"
/db_xref="SGD:S000004975"
/db_xref="GeneID:855701"
/translation="MSGRGKGGKGLGKGGAKRHRKILRDNIQGITKPAIRRLARRGGV
KRISGLIYEEVRAVLKSFLESVIRDSVTYTEHAKRKTVTSLDVVYALKRQGRTLYGFG
G"
gene complement(577205..578773)
/gene="KTR5"
/locus_tag="YNL029C"
/db_xref="GeneID:855703"
mRNA complement(577205..578773)
/gene="KTR5"
/locus_tag="YNL029C"
/product="Ktr5p"
/transcript_id="NM_001182868.3"
/db_xref="GI:398365364"
/db_xref="GeneID:855703"
CDS complement(577205..578773)
/gene="KTR5"
/locus_tag="YNL029C"
/EC_number="2.4.1.131"
/note="Putative mannosyltransferase involved in protein
glycosylation; member of the KRE2/MNT1 mannosyltransferase
family"
/codon_start=1
/product="Ktr5p"
/protein_id="NP_014369.3"
/db_xref="GI:398365365"
/db_xref="SGD:S000004974"
/db_xref="GeneID:855703"
/translation="MLLIRRTINAFLGCIHCNLTATCILIAFVITMYVVLVSEPASVD
GTMGNFLPFSKMDLATKRDRPFYSNCVNTQDYLLNPSYIKQNASFVMLTRNGELEDVI
KTINSIEEHFNQWFHYPYVFLNDQPFEEDFKAKVRDVTVGALVEFGTIDEISWNFPSD
VKDTFEFYNAIEDQGDRSILYGNLESYHKMCRFYSGLFYKHPLVQKYEWYWRLEPDVE
FFCDITYDPFLEMLRTNKKYGFTIIIPELYWTVPNLFRHTKSFISQKGVTLGSLWKLF
TKDYDIFESDDPELRDWINYDFQAKAKISEKIAIEQLLKKGDDFQQINDDKEGIMNLI
HKARSRKHIVEDKFFNEEYNLCHFWSNFEIARLSVFDNDIYNSFFQYLEKSGGFWKER
WGDAPVHSIGLSLTLDLDDVHYFRDIGYRHSTIQHCPHNAMGNEEFSYLASDSKFKRK
NAAYDEGREFGCGCRCRCPKKKREIEDSMGFCVNIWVNLLNQQRGHERHVEALNGNEM
EEHIREDYLRQFGN"
gene 579580..581616
/gene="CRZ1"
/locus_tag="YNL027W"
/gene_synonym="HAL8; TCN1"
/db_xref="GeneID:855704"
mRNA 579580..581616
/gene="CRZ1"
/locus_tag="YNL027W"
/gene_synonym="HAL8; TCN1"
/product="Crz1p"
/transcript_id="NM_001182866.1"
/db_xref="GI:296147738"
/db_xref="GeneID:855704"
CDS 579580..581616
/gene="CRZ1"
/locus_tag="YNL027W"
/gene_synonym="HAL8; TCN1"
/note="Transcription factor that activates transcription
of genes involved in stress response; nuclear localization
is positively regulated by calcineurin-mediated
dephosphorylation"
/codon_start=1
/product="Crz1p"
/protein_id="NP_014371.1"
/db_xref="GI:6324301"
/db_xref="SGD:S000004972"
/db_xref="GeneID:855704"
/translation="MSFSNGNMASYMTSSNGEEQSINNKNDIDDNSAYRRNNFRNSSN
SGSHTFQLSDLDLDVDMRMDSANSSEKISKNLSSGIPDSFDSNVNSLLSPSSGSYSAD
LNYQSLYKPDLPQQQLQQQQLQQQQQQQQQQQQQQQKQTPTLKVEQSDTFQWDDILTP
ADNQHRPSLTNQFLSPRSNYDGTTRSSGIDSNYSDTESNYHTPYLYPQDLVSSPAMSH
LTANNDDFDDLLSVASMNSNYLLPVNSHGYKHISNLDELDDLLSLTYSDNNLLSASNN
SDFNNSNNGIINTADTQNSTIAINKSKVGTNQKMLLTIPTSSTPSPSTHAAPVTPIIS
IQEFNEGHFPVKNEDDGTLQLKVRDNESYSATNNNNLLRPDDNDYNNEALSDIDRSFE
DIINGRKLKLKKSRRRSSQTSNNSFTSRRSSRSRSISPDEKAKSISANREKLLEMADL
LPSSENDNNRERYDNDSKTSYNTINSSNFNEDNNNNNLLTSKPKIESGIVNIKNELDD
TSKDLGILLDIDSLGQFEQKVGFKNDDNHENNDNGTFSVKKNDNLEKLDSVTNNRKNP
ANFACDVCGKKFTRPYNLKSHLRTHTNERPFICSICGKAFARQHDRKRHEDLHTGKKR
YVCGGKLKDGKPWGCGKKFARSDALGRHFKTESGRRCITPLYEEARQEKSGQES"
gene 581920..583374
/gene="SAM50"
/locus_tag="YNL026W"
/gene_synonym="OMP85; TOB55"
/db_xref="GeneID:855705"
mRNA 581920..583374
/gene="SAM50"
/locus_tag="YNL026W"
/gene_synonym="OMP85; TOB55"
/product="Sam50p"
/transcript_id="NM_001182865.1"
/db_xref="GI:296147739"
/db_xref="GeneID:855705"
CDS 581920..583374
/gene="SAM50"
/locus_tag="YNL026W"
/gene_synonym="OMP85; TOB55"
/note="Essential component of the Sorting and Assembly
Machinery (SAM or TOB complex) of the mitochondrial outer
membrane, which binds precursors of beta-barrel proteins
and facilitates their outer membrane insertion; homologous
to bacterial Omp85"
/codon_start=1
/product="Sam50p"
/protein_id="NP_014372.1"
/db_xref="GI:6324302"
/db_xref="SGD:S000004971"
/db_xref="GeneID:855705"
/translation="MTSSSGVDNEISLDSPMPIFNESSTLKPIRVAGVVTTGTDHIDP
SVLQAYLDDTIMKSITLGQLVKNADVLNKRLCQHHIALNAKQSFHFQGNTYISDEKET
HDVVPLMEVVSQLDILPPKTFTAKTGTNFGNDNDAEAYLQFEKLIDKKYLKLPTRVNL
EILRGTKIHSSFLFNSYSSLSPQSILNLKVFSQFYNWNTNKGLDIGQRGARLSLRYEP
LFLHKLLHNPHSNESPTLFHEWFLETCWRSTKICSQGTSAPYMYSGTMLSQAGDQLRT
ILGHTFVLDKRDHIMCPTKGSMLKWSNELSPGKHLKTQLELNSVKSWMNDDFITFSTT
IKTGYLKNLSSQQSLPVHICDKFQSGGPSDIRGFQTFGLGPRDLYDAVGGDAFVSYGL
SVFSRLPWKKVEKSNFRLHWFFNGGKLVNHDNTSLGNCIGQLSKEHSTSTGIGLVLRH
PMARFELNFTLPITAHENDLIRKGFQFGLGLAFL"
gene complement(584320..585291)
/gene="SSN8"
/locus_tag="YNL025C"
/gene_synonym="GIG3; NUT9; RYE2; SRB11; UME3"
/db_xref="GeneID:855706"
mRNA complement(584320..585291)
/gene="SSN8"
/locus_tag="YNL025C"
/gene_synonym="GIG3; NUT9; RYE2; SRB11; UME3"
/product="Ssn8p"
/transcript_id="NM_001182864.3"
/db_xref="GI:398365378"
/db_xref="GeneID:855706"
CDS complement(584320..585291)
/gene="SSN8"
/locus_tag="YNL025C"
/gene_synonym="GIG3; NUT9; RYE2; SRB11; UME3"
/note="Cyclin-like component of the RNA polymerase II
holoenzyme, involved in phosphorylation of the RNA
polymerase II C-terminal domain; involved in glucose
repression and telomere maintenance"
/codon_start=1
/product="Ssn8p"
/protein_id="NP_014373.3"
/db_xref="GI:398365379"
/db_xref="SGD:S000004970"
/db_xref="GeneID:855706"
/translation="MSGSFWTSTQRHHWQYTKASLAKERQKLWLLECQLFPQGLNIVM
DSKQNGIEQSITKNIPITHRDLHYDKDYNLRIYCYFLIMKLGRRLNIRQYALATAHIY
LSRFLIKASVREINLYMLVTTCVYLACKVEECPQYIRTLVSEARTLWPEFIPPDPTKV
TEFEFYLLEELESYLIVHHPYQSLKQIVQVLKQPPFQITLSSDDLQNCWSLINDSYIN
DVHLLYPPHIIAVACLFITISIHGKPTKGSSLASAASEAIRDPKNSSSPVQIAFNRFM
AESLVDLEEVMDTIQEQITLYDHWDKYHEQWIKFLLHTLYLRPASAI"
gene 585587..585926
/locus_tag="NME1"
/db_xref="GeneID:9164967"
ncRNA 585587..585926
/locus_tag="NME1"
/ncRNA_class="snoRNA"
/product="NME1"
/note="RNA component of RNase MRP, which cleaves pre-rRNA
and has a role in cell cycle-regulated degradation of
daughter cell-specific mRNAs; human ortholog is implicated
in cartilage-hair hypoplasia (CHH)"
/db_xref="SGD:S000007436"
/db_xref="GeneID:9164967"
gene 586090..586175
/locus_tag="snR66"
/db_xref="GeneID:9164968"
ncRNA 586090..586175
/locus_tag="snR66"
/ncRNA_class="snoRNA"
/product="SNR66"
/note="C/D box small nucleolar RNA (snoRNA), guides
2'-O-methylation of large subunit (LSU) rRNA at position
U2417"
/db_xref="SGD:S000006457"
/db_xref="GeneID:9164968"
gene complement(586602..586820)
/gene="KSH1"
/locus_tag="YNL024C-A"
/db_xref="GeneID:1466516"
mRNA complement(586602..586820)
/gene="KSH1"
/locus_tag="YNL024C-A"
/product="Ksh1p"
/transcript_id="NM_001184619.3"
/db_xref="GI:398365384"
/db_xref="GeneID:1466516"
CDS complement(586602..586820)
/gene="KSH1"
/locus_tag="YNL024C-A"
/note="Essential protein suggested to function early in
the secretory pathway; inviability is suppressed by
overexpression of Golgi protein Tvp23p; ortholog of human
Kish"
/codon_start=1
/product="Ksh1p"
/protein_id="NP_878158.3"
/db_xref="GI:398365385"
/db_xref="SGD:S000028698"
/db_xref="GeneID:1466516"
/translation="MSALFNFRSLLQVILLLICSCSYVHGQWPSLLDRYKNHEVLGAF
WKMARVGERASPYVSLACILMAISQFNS"
gene complement(587107..587847)
/locus_tag="YNL024C"
/db_xref="GeneID:855707"
mRNA complement(587107..587847)
/locus_tag="YNL024C"
/product="hypothetical protein"
/transcript_id="NM_001182863.1"
/db_xref="GI:296147742"
/db_xref="GeneID:855707"
CDS complement(587107..587847)
/locus_tag="YNL024C"
/note="Putative methyltransferase; has seven beta-strand
methyltransferase motif; green fluorescent protein
(GFP)-fusion protein localizes to the cytoplasm; despite
similarity to methyltransferases, null mutant does not
display alterations in lysine methylation pattern"
/codon_start=1
/product="hypothetical protein"
/protein_id="NP_014374.1"
/db_xref="GI:6324304"
/db_xref="SGD:S000004969"
/db_xref="GeneID:855707"
/translation="MESIFGGFGDLVVPRPKEHLGQTDLSFGGKLLPALKICEDGGES
GCGGKVWIAGELLCEYILEKSVDHLLSKTVNGTKQFKKVLELGSGTGLVGLCVGLLEK
NTFHDGTKVYVTDIDKLIPLLKRNIELDEVQYEVLARELWWGEPLSADFSPQEGAMQA
NNVDLVLAADCVYLEEAFPLLEKTLLDLTHCINPPVILMAYKKRRKADKHFFNKIKRN
FDVLEITDFSKFEHYLKERTHLFQLIRK"
gene complement(588263..591160)
/gene="FAP1"
/locus_tag="YNL023C"
/db_xref="GeneID:855708"
mRNA complement(588263..591160)
/gene="FAP1"
/locus_tag="YNL023C"
/product="Fap1p"
/transcript_id="NM_001182862.1"
/db_xref="GI:296147743"
/db_xref="GeneID:855708"
CDS complement(588263..591160)
/gene="FAP1"
/locus_tag="YNL023C"
/note="Protein that binds to Fpr1p, conferring rapamycin
resistance by competing with rapamycin for Fpr1p binding;
accumulates in the nucleus upon treatment of cells with
rapamycin; has similarity to D. melanogaster shuttle craft
and human NFX1"
/codon_start=1
/product="Fap1p"
/protein_id="NP_014375.1"
/db_xref="GI:6324305"
/db_xref="SGD:S000004968"
/db_xref="GeneID:855708"
/translation="MTEHESLGLEQNQDGGDTYRHHNLSDGCISSVEDANEQPSSYEE
ESDDDMQYYERAIQEISSGDSYVCMICTVEMDYTCQMFACKRCYRVFDYGCIREWALK
STEKTVDRIWKCPNCYYVSKRVPVKNRPTCWCGKVVNPDPNPLDPNSCGQTCNASTCM
HGCSKICHLGPHPECTRMVEIMCHCGKHSKSIFCYQSKVMKKNFNCQEVCGLPLSCSI
HTCKKKCHPGLCGPCPEMIISKDSPKKQIKCYCGNHTRANIKCSETKFPKSGKSSKDE
NGNRWIGVFACADNRVVDYSCRKHSFIESCISPPTINGEKACPFLPSSLKTCPCGRTA
LEELTKPRKHCDDPIPTCDSRCGKPLKCGKHSCPFTCHDKACMEPCLQIDSVKCACEQ
STFSVPCGFQGRPRCNIKCESLMSCRRHRCTDRCCSGRPSAIRRKKNLFRTQDLLDES
LVEAKHICLKPCNLTLSCGIHKCQRKCHPGKCPPCLESDSNDLVCPCGNTVVPAPVRC
GTKLPTCNHPCIKVVRGESTCGHKPMPHTCHSLDVSCPPCTETVFKPCKCGKKTKVRT
VCFQTDVSCGIKCGIPLSYCYHTCQKTCHLPGNCQKVCKQTCGQKRLNCNHECPKPCH
GKTECPDLPCATLVKIYCKCGRIKKSVTCGAKSDRVSVTESSVLDCNEECEALKRLKE
LKEAFGIKEETNNFTSNELDALKKLVSVATTFEELQLPFTEAALSVYSKQERWCSQIE
AILNKLMDDKTRSSLHFKPMRPPQRHFIRELAKAYGLYSESQDREPMRSVFIKKEDNG
ASNKPVLSLAEAYPLYESFKQLQKERKAQEFQARTTAKLINFEVQDTEPKVEVAKKNG
FLVQNLVAGNTAEDLRRFFEPHLKHTLVVNPQYLILDDGKTALVYPENYETASVNTER
DMELLVGHFDFMAKEAFLADSISLCSTEEELERRLDTPVIQEDSPVMDNNT"
STS 588729..588831
/standard_name="px-17d12"
/db_xref="UniSTS:257343"
gene complement(591427..592899)
/locus_tag="YNL022C"
/db_xref="GeneID:855709"
mRNA complement(591427..592899)
/locus_tag="YNL022C"
/product="hypothetical protein"
/transcript_id="NM_001182861.3"
/db_xref="GI:398365406"
/db_xref="GeneID:855709"
CDS complement(591427..592899)
/locus_tag="YNL022C"
/note="Putative cytosine 5-methyltransferase, contains
seven beta-strand methyltransferase motif similar to
NOP2/YNL061W; green fluorescent protein (GFP)-fusion
protein localizes to the nucleus; predicted to be involved
in ribosome biogenesis"
/codon_start=1
/product="hypothetical protein"
/protein_id="NP_014376.3"
/db_xref="GI:398365407"
/db_xref="SGD:S000004967"
/db_xref="GeneID:855709"
/translation="MNFYRDATWVLEDIEKEAAKERISGSMQTLVLKSCKRYKLKSNP
KHIYAVLDSCWKYKPYLEKVMKKAHILEDIPKKKGKPLFSRLTLLLLCHDLLLSKQKR
IQMGKHPIKDYVLKFKSPLHSEMVKLKLKLKVRELSELVLSEDISNDLPPVRWIRINP
LKCHPNGETEPVLAELRKKFTLKVDKWSELVPGSIYYDEFIPNLFGIHPSDKITAHEL
YKHGKIIIQDRASCFPAHILNPGPSDIVIDSCSAPGNKTTHTASYIYPEPPKDNNTRI
YAFEKDPERAKVLQKMIKIAGCSPNISVNVGDFTKLATPEKYKDVTCFIVDPSCSGSG
IFGRKFFDSFNRRKIDDKDDDGGIVPDEQEEFIAKEELQTRLAKLSSFQFQMVKHAMS
FPAAKKIVYSTCSIHAEENERVVIDLLLDKSVREWGWKVAPKREVIPSWPRRGKVEEF
EEVFRDGVTYDPQQLAEGCIRALPKSDGGIGFFAVCFERD"
gene 593227..595347
/gene="HDA1"
/locus_tag="YNL021W"
/db_xref="GeneID:855710"
mRNA 593227..595347
/gene="HDA1"
/locus_tag="YNL021W"
/product="Hda1p"
/transcript_id="NM_001182860.1"
/db_xref="GI:296147745"
/db_xref="GeneID:855710"
CDS 593227..595347
/gene="HDA1"
/locus_tag="YNL021W"
/note="Putative catalytic subunit of a class II histone
deacetylase complex that also contains Hda2p and Hda3p;
Hda1p interacts with the Hda2p-Hda3p subcomplex to form an
active tetramer; deletion increases histone H2B, H3 and H4
acetylation"
/codon_start=1
/product="Hda1p"
/protein_id="NP_014377.1"
/db_xref="GI:6324307"
/db_xref="SGD:S000004966"
/db_xref="GeneID:855710"
/translation="MDSVMVKKEVLENPDHDLKRKLEENKEEENSLSTTSKSKRQVIV
PVCMPKIHYSPLKTGLCYDVRMRYHAKIFTSYFEYIDPHPEDPRRIYRIYKILAENGL
INDPTLSGVDDLGDLMLKIPVRAATSEEILEVHTKEHLEFIESTEKMSREELLKETEK
GDSVYFNNDSYASARLPCGGAIEACKAVVEGRVKNSLAVVRPPGHHAEPQAAGGFCLF
SNVAVAAKNILKNYPESVRRIMILDWDIHHGNGTQKSFYQDDQVLYVSLHRFEMGKYY
PGTIQGQYDQTGEGKGEGFNCNITWPVGGVGDAEYMWAFEQVVMPMGREFKPDLVIIS
SGFDAADGDTIGQCHVTPSCYGHMTHMLKSLARGNLCVVLEGGYNLDAIARSALSVAK
VLIGEPPDELPDPLSDPKPEVIEMIDKVIRLQSKYWNCFRRRHANSGCNFNEPINDSI
ISKNFPLQKAIRQQQQHYLSDEFNFVTLPLVSMDLPDNTVLCTPNISESNTIIIVVHD
TSDIWAKRNVISGTIDLSSSVIIDNSLDFIKWGLDRKYGIIDVNIPLTLFEPDNYSGM
ITSQEVLIYLWDNYIKYFPSVAKIAFIGIGDSYSGIVHLLGHRDTRAVTKTVINFLGD
KQLKPLVPLVDETLSEWYFKNSLIFSNNSHQCWKENESRKPRKKFGRVLRCDTDGLNN
IIEERFEEATDFILDSFEEWSDEE"
gene complement(595623..597539)
/gene="ARK1"
/locus_tag="YNL020C"
/db_xref="GeneID:855711"
mRNA complement(595623..597539)
/gene="ARK1"
/locus_tag="YNL020C"
/product="Ark1p"
/transcript_id="NM_001182859.1"
/db_xref="GI:296147746"
/db_xref="GeneID:855711"
CDS complement(595623..597539)
/gene="ARK1"
/locus_tag="YNL020C"
/EC_number="2.7.11.1"
/note="Serine/threonine protein kinase involved in
regulation of the cortical actin cytoskeleton; involved in
control of endocytosis"
/codon_start=1
/product="Ark1p"
/protein_id="NP_014378.1"
/db_xref="GI:6324308"
/db_xref="SGD:S000004965"
/db_xref="GeneID:855711"
/translation="MNQPQIGTYNVGTQLTVGSHQVEIIKYLTSGGFAQVYSALINPP
DPHSNSSVACLKRVIVPDKPSLNTLRAEVDAMRLLKNNRYVVSYIDSHAAKAMLHNGS
YEVFVLMEYCERGGLIDFMNTRLQNRLHEFEILQIMSQVTQGVAAMHALQPPLIHRDI
KIENVLISANNEYKLCDFGSVCGIIRPPRNSQELSYVQQDILKNTTAQYRSPEMIDTF
RGLPIDEKSDIWALGIFLYKLCYYTTPFEKGGDLAILSGKFEFPLYPNYSEQLKGLIR
DILVQDPRHRPNVYQLLKRISIMQNVPCPINDIQVVQAPSSHLNLTELHQLSATQNIL
SLNSPTTMENTMPNATFQISMADNTTTAQMHPNRKPSQIAYDASFSNSAKGSQPLFDK
SQNMYHALDPPLVEPLASSVSNNDNELKANSATKLKQAIVSEAHTFRQNNSIDFPLQN
IIPQYEDSSSSSDESYSGDVDELKKTRSLGSYSTRGNIKKNQSVKESLTSSSLPGTSF
TPTSTKVNLKHENSPFKSTFVNTIDNSKDDLNKPSYEDLDVSKQNLKNSIQQRMIDKL
NSSEESFNARKMSKVKLHEKGEIDKPTMLKSSGPISKDKKTKPTPPPKPSHLKPKPPP
KPLLLAGRKLSLDK"
gene complement(598376..599230)
/locus_tag="YNL019C"
/db_xref="GeneID:855712"
mRNA complement(598376..599230)
/locus_tag="YNL019C"
/product="hypothetical protein"
/transcript_id="NM_001182858.3"
/db_xref="GI:398365426"
/db_xref="GeneID:855712"
CDS complement(598376..599230)
/locus_tag="YNL019C"
/codon_start=1
/product="hypothetical protein"
/protein_id="NP_014379.3"
/db_xref="GI:398365427"
/db_xref="SGD:S000004964"
/db_xref="GeneID:855712"
/translation="MLYSRESRTTVLFLALVTSLTVLCHSVDVTTVFTTSTITEITTV
TAAPQPQNKAETALNTATNIIQTMQFLFNCAPFKWKGPLKITSCALNFIVLLLTAWGY
LLKYLQENKLNSDADMEKMVGLGFGEMVGRIFGKGVGKAFTKMDITQKLVYPFEGSNR
QKCLLMTVGENSIVPFHDLSTEICFDQYTLDSLSHHNHGSISILDAGSVSALGFADIS
SKMPSVSELYTLFGDYTIEVLGGITKLASTLNREDWQGERNGFAVLSRDRPNQTLLSV
HMYSSSLL"
gene complement(599936..601774)
/locus_tag="YNL018C"
/db_xref="GeneID:855713"
mRNA complement(599936..601774)
/locus_tag="YNL018C"
/product="hypothetical protein"
/transcript_id="NM_001182857.3"
/db_xref="GI:398365432"
/db_xref="GeneID:855713"
CDS complement(599936..601774)
/locus_tag="YNL018C"
/codon_start=1
/product="hypothetical protein"
/protein_id="NP_014380.3"
/db_xref="GI:398365433"
/db_xref="SGD:S000004963"
/db_xref="GeneID:855713"
/translation="MSTSFQEFKAFCNKVGLDFQWLNLQSSKSVPENGSSEGFSAVSD
TVQENIRPATEPLNVNQSKDPVSNFFYDVKNAPLWNVYKRNHSGHSSAEACSGVSSRQ
APKNIPEAMVKETVLSNHDNVTIINELLPTSSAMHQEESTAMTTSYLLSHSVNDTCNV
MFSSSSHNRAMLPSSLVQRNNATTSPTTDSASENNESVPSLTSSVSTSSSVYSSWNPP
HSPHISSFPDGNFASLNAEVTCFDFRRTKDSRTKETNESIIPTEIYCPTNSTDHHKHY
PSRKSKQDACAPAPCNQNISCSVVSTAEFSQSNHTLTTVVPSYMQQYLDRPQNWFESK
MGKYCPLFLRSTKNIDYDSLEFKFERKMIAVQYLLLDEQSEPRRYYNPSNKSIPFWKR
PFNFDTMPSYDQLMEEAECRFYSYQYKYEGFQRIEPYSISCPWKNTQREIDLVLDHIH
FSLDVGEKKSLNRKGNITLDTLDSKVDPNIQIKPYQIFPSNNLVYEGLPHPAEQSLIL
SPDTSLIERAFQALIDICKESIPSSNDCSTRNNNSAPQLTVPEPSKPCRLLLVRESRT
ATELKTNKKLWLHSQRRNIEVTVPMHPSERGTKSWLRKWLSTFVHQ"
gene 602312..602385
/locus_tag="tI(AAU)N2"
/db_xref="GeneID:855714"
tRNA 602312..602385
/locus_tag="tI(AAU)N2"
/product="tRNA-Ile"
/note="Isoleucine tRNA (tRNA-Ile), predicted by
tRNAscan-SE analysis"
/db_xref="SGD:S000006610"
/db_xref="GeneID:855714"
gene 602907..604268
/gene="PUB1"
/locus_tag="YNL016W"
/gene_synonym="RNP1"
/db_xref="GeneID:855716"
mRNA 602907..604268
/gene="PUB1"
/locus_tag="YNL016W"
/gene_synonym="RNP1"
/product="Pub1p"
/transcript_id="NM_001182855.1"
/db_xref="GI:296147749"
/db_xref="GeneID:855716"
CDS 602907..604268
/gene="PUB1"
/locus_tag="YNL016W"
/gene_synonym="RNP1"
/note="Poly (A)+ RNA-binding protein; abundant
mRNP-component protein that binds mRNA and is required for
stability of many mRNAs; component of glucose deprivation
induced stress granules, involved in P-body-dependent
granule assembly; protein abundance increases in response
to DNA replication stress"
/codon_start=1
/product="Pub1p"
/protein_id="NP_014382.1"
/db_xref="GI:6324312"
/db_xref="SGD:S000004961"
/db_xref="GeneID:855716"
/translation="MSENNEEQHQQQQQQQPVAVETPSAVEAPASADPSSEQSVAVEG
NSEQAEDNQGENDPSVVPANAITGGRETSDRVLYVGNLDKAITEDILKQYFQVGGPIA
NIKIMIDKNNKNVNYAFVEYHQSHDANIALQTLNGKQIENNIVKINWAFQSQQSSSDD
TFNLFVGDLNVNVDDETLRNAFKDFPSYLSGHVMWDMQTGSSRGYGFVSFTSQDDAQN
AMDSMQGQDLNGRPLRINWAAKRDNNNNNNYQQRRNYGNNNRGGFRQYNSNNNNNMNM
GMNMNMNMNMNNSRGMPPSSMGMPIGAMPLPSQGQPQQSQTIGLPPQVNPQAVDHIIR
SAPPRVTTAYIGNIPHFATEADLIPLFQNFGFILDFKHYPEKGCCFIKYDTHEQAAVC
IVALANFPFQGRNLRTGWGKERSNFMPQQQQQGGQPLIMNDQQQPVMSEQQQQQQQQQ
QQQ"
gene 605384..605611
/gene="PBI2"
/locus_tag="YNL015W"
/gene_synonym="LMA1"
/db_xref="GeneID:855717"
mRNA 605384..605611
/gene="PBI2"
/locus_tag="YNL015W"
/gene_synonym="LMA1"
/product="Pbi2p"
/transcript_id="NM_001182854.1"
/db_xref="GI:296147750"
/db_xref="GeneID:855717"
CDS 605384..605611
/gene="PBI2"
/locus_tag="YNL015W"
/gene_synonym="LMA1"
/note="Cytosolic inhibitor of vacuolar proteinase B
(PRB1); required for efficient vacuole inheritance; with
thioredoxin forms protein complex LMA1, which assists in
priming SNARE molecules and promotes vacuole fusion;
protein abundance increases in response to DNA replication
stress"
/codon_start=1
/product="Pbi2p"
/protein_id="NP_014383.1"
/db_xref="GI:6324313"
/db_xref="SGD:S000004960"
/db_xref="GeneID:855717"
/translation="MTKNFIVTLKKNTPDVEAKKFLDSVHHAGGSIVHEFDIIKGYTI
KVPDVLHLNKLKEKHNDVIENVEEDKEVHTN"
gene 606319..609453
/gene="HEF3"
/locus_tag="YNL014W"
/gene_synonym="ZRG7"
/db_xref="GeneID:855718"
mRNA 606319..609453
/gene="HEF3"
/locus_tag="YNL014W"
/gene_synonym="ZRG7"
/product="translation elongation factor EF-3"
/transcript_id="NM_001182853.3"
/db_xref="GI:398365454"
/db_xref="GeneID:855718"
CDS 606319..609453
/gene="HEF3"
/locus_tag="YNL014W"
/gene_synonym="ZRG7"
/note="Translational elongation factor EF-3; paralog of
YEF3 and member of the ABC superfamily; stimulates EF-1
alpha-dependent binding of aminoacyl-tRNA by the ribosome;
normally expressed in zinc deficient cells"
/codon_start=1
/product="translation elongation factor EF-3"
/protein_id="NP_014384.3"
/db_xref="GI:398365455"
/db_xref="SGD:S000004959"
/db_xref="GeneID:855718"
/translation="MSDSQQSITVLEELFRKLETATSETREGISSELSSFLNGNIIEH
DVPEVFFDEFQKAIQSKQKALNTLGAVAYIANETNLSPSVEPYIVATVPSVCSKAGSK
DNDVQLAATKALKAIASAVNPVAVKALLPHLIHSLETSNKWKEKVAVLEVISVLVDAA
KEQIALRMPELIPVLSESMWDTKKGVKEAATTTITKATETVDNKDIERFIPKLIECIA
NPNEVPETVHLLGATTFVAEVTPATLSIMVPLLSRGLAERETSIKRKAAVIIDNMCKL
VEDPQVVAPFLGKLLPGLKNNFATIADPEAREVTLKALKTLRRVGNVGEDDVLPEISH
AGDVSTTLGVIKELLEPEKVAPRFTIVVEYIAAIAANLIDERIIDQQTWFTHVTPYMT
IFLHEKTAKEILDDFRKRAVDNIPVGPNFQDEEDEGEDLCNCEFSLAYGAKILLNKTQ
LRLKRGRRYGLCGPNGAGKSTLMRSIANGQVDGFPTQDECRTVYVEHDIDNTHSDMSV
LDFVYSGNVGTKDVITSKLKEFGFSDEMIEMPIASLSGGWKMKLALARAVLKDADILL
LDEPTNHLDTVNVEWLVNYLNTCGITSVIVSHDSGFLDKVCQYIIHYEGLKLRKYKGN
LSEFVQKCPTAQSYYELGASDLEFQFPTPGYLEGVKTKQKAIVKVSNMTFQYPGTTKP
QVSDVTFQCSLSSRIAVIGPNGAGKSTLINVLTGELLPTSGEVYTHENCRIAYIKQHA
FAHIESHLDKTPSEYIQWRFQTGEDRETMDRANRQINENDAEAMNKIFKIEGTPRRVA
GIHSRRKFKNTYEYECSFLLGENIGMKSERWVPMMSVDNAWLPRGELIESHSKMVAEI
DMKEALASGQFRALTRKEIELHCAMLGLDSELVSHSRIRGLSGGQKVKLVLAACTWQR
PHLIVLDEPTNYLDRDSLGALSKALKAFEGGVIIITHSAEFTKNLTDEVWAVKDGKMT
PSGHNWVAGQGAGPRIEKKEEEGDKFDAMGNKINSGKKKSKLSSAELRKKKKERMKKK
KEMGDEYVSSDEDF"
rep_origin 609463..609710
/note="ARS1424;
Autonomously Replicating Sequence"
/db_xref="SGD:S000118391"
gene 609686..611665
/gene="SPO1"
/locus_tag="YNL012W"
/db_xref="GeneID:855720"
mRNA join(609686..609790,609875..611665)
/gene="SPO1"
/locus_tag="YNL012W"
/product="Spo1p"
/transcript_id="NM_001182851.1"
/db_xref="GI:296147752"
/db_xref="GeneID:855720"
CDS join(609686..609790,609875..611665)
/gene="SPO1"
/locus_tag="YNL012W"
/EC_number="3.1.1.-"
/note="Meiosis-specific prospore protein; required for
meiotic spindle pole body duplication and separation;
required to produce bending force necessary for proper
prospore membrane assembly during sporulation; has
similarity to phospholipase B"
/codon_start=1
/product="Spo1p"
/protein_id="NP_014386.2"
/db_xref="GI:9755342"
/db_xref="SGD:S000004957"
/db_xref="GeneID:855720"
/translation="MQKLLFVFSVLLTVVLATAPFQVQCPSSPLIREAKHELCPEETL
YLKKKKIKTKNKLIQFLKSLTEAKFSSKFYKRVLKDPPKIGIAISGGGYRSMLVGTGF
ISQMNDYGLFEYSDYIAGLSGGSWILMDLVVQNFEVKSLLQEWDLEEDLLLGIPEFDI
SEEEIVTNAKKEYNDNDLKMKKRQGGSLITSSSNFYEQIEEIMNSIEEIPEDYMITKR
NLNPLARLKKIFFPNNTFTGTDAKIETFKKVLDFYKSLHLKIKPKKMEGFQISFTDYW
GKAIVQRLKKNFDDDPNHSFSFSKLVNSSKKFKECSVPIPIFVANCKNGLLSNVIFEF
TPFEFGSWENILRLFVKLPYLGSKIVSGKAEKCINNFDDLGFITATSSSIFNNVLIFI
WNLASQSSREAMKALNMVMGIFGLGKEEIFSISKDSSRLETDYAVYQPNPFYLYPEKD
NVLTNKNHLYLVDGGEDGENIPLRTLVIPERELDVIFVLDSSSDIDNYPNGSKLKRIF
EKLDEENVHYQFPNNVKTFTHPIVIGCNATKRTGHDSFLPIIIYHANANHGNASNTST
FKITYNQSEVSSMLPTGRGVFSNDYDLYYKNCLGCILTKRTMDRLPRKKKFSPFCLQC
FKDYCYS"
gene complement(611836..613170)
/locus_tag="YNL011C"
/db_xref="GeneID:855721"
mRNA complement(611836..613170)
/locus_tag="YNL011C"
/product="hypothetical protein"
/transcript_id="NM_001182850.1"
/db_xref="GI:296147753"
/db_xref="GeneID:855721"
CDS complement(611836..613170)
/locus_tag="YNL011C"
/note="hypothetical protein; YNL011C is not an essential
gene"
/codon_start=1
/product="hypothetical protein"
/protein_id="NP_014387.1"
/db_xref="GI:6324317"
/db_xref="SGD:S000004956"
/db_xref="GeneID:855721"
/translation="MNVVVCSGGTATNSLTPCFSNISILKGHELTYILPISDNGGSTS
EILRIVGGPAIGDIRSRIVRLLQDEQLVELFGHRLPNDKLLAKKEWNEIVEGSHPIWK
NISIEVKEMCRSFIIHMQAELLKKIKHSNPFQFESASIGNFFLTGARLFLGSLDASIE
LMMRIGRCSPLVHVIPCINTNHTHHISALLTNGEMITGQSQISHPSKSVPKDNSIAHS
AKFIHLLGSYDDHLKILLDDEEEEAEEEYANPIYILPELKNSQLHFDKLDESQNLPAP
VHRILYINPYGEEIKPMGNPRAISKVKKADMVVYSIGSLMTSLLPILILGNLAEVILE
SNNTKKVLLINNKYDREVFGLDGLHYVQMIIDSMSRAIAGYRQSKGVHSENDDFEWQD
FITDIVYLKNGEIEIDETIFEKHSIRCHQIASSDKMESEELEKVLNQIGLKN"
gene 613635..614360
/locus_tag="YNL010W"
/db_xref="GeneID:855722"
mRNA 613635..614360
/locus_tag="YNL010W"
/product="hypothetical protein"
/transcript_id="NM_001182849.3"
/db_xref="GI:398365466"
/db_xref="GeneID:855722"
CDS 613635..614360
/locus_tag="YNL010W"
/note="hypothetical protein with similarity to
phosphoserine phosphatases; green fluorescent protein
(GFP)-fusion protein localizes to the cytoplasm and
nucleus; homozygous diploid mutant shows an increase in
glycogen accumulation"
/codon_start=1
/product="hypothetical protein"
/protein_id="NP_014388.3"
/db_xref="GI:398365467"
/db_xref="SGD:S000004955"
/db_xref="GeneID:855722"
/translation="MVKAVIFTDFDGTVTLEDSNDYLTDTLGFGKEKRLKVFEGVLDD
TKSFRQGFMEMLESIHTPFPECIKILEKKIRLDPGFKDTFEWAQENDVPVIVVSSGMK
PIIKVLLTRLVGQESIHKIDIVSNEVEIDAHDQWKIIYKDESPFGHDKSRSIDAYKKK
FESTLKAGEQRPVYFYCGDGVSDLSAAKECDLLFAKRGKDLVTYCKKQNVPFHEFDTF
KDILASMKQVLAGEKTVAELMEN"
gene 614821..616083
/gene="IDP3"
/locus_tag="YNL009W"
/db_xref="GeneID:855723"
mRNA 614821..616083
/gene="IDP3"
/locus_tag="YNL009W"
/product="isocitrate dehydrogenase (NADP(+)) IDP3"
/transcript_id="NM_001182848.3"
/db_xref="GI:398365478"
/db_xref="GeneID:855723"
CDS 614821..616083
/gene="IDP3"
/locus_tag="YNL009W"
/EC_number="1.1.1.42"
/note="Peroxisomal NADP-dependent isocitrate
dehydrogenase, catalyzes oxidation of isocitrate to
alpha-ketoglutarate with the formation of NADP(H+),
required for growth on unsaturated fatty acids"
/codon_start=1
/product="isocitrate dehydrogenase (NADP(+)) IDP3"
/protein_id="NP_014389.3"
/db_xref="GI:398365479"
/db_xref="SGD:S000004954"
/db_xref="GeneID:855723"
/translation="MSKIKVVHPIVEMDGDEQTRVIWKLIKEKLILPYLDVDLKYYDL
SIQERDRTNDQVTKDSSYATLKYGVAVKCATITPDEARMKEFNLKEMWKSPNGTIRNI
LGGTVFREPIIIPKIPRLVPHWEKPIIIGRHAFGDQYRATDIKIKKAGKLRLQFSSDD
GKENIDLKVYEFPKSGGIAMAMFNTNDSIKGFAKASFELALKRKLPLFFTTKNTILKN
YDNQFKQIFDNLFDKEYKEKFQALKITYEHRLIDDMVAQMLKSKGGFIIAMKNYDGDV
QSDIVAQGFGSLGLMTSILITPDGKTFESEAAHGTVTRHFRKHQRGEETSTNSIASIF
AWTRAIIQRGKLDNTDDVIKFGNLLEKATLDTVQVGGKMTKDLALMLGKTNRSSYVTT
EEFIDEVAKRLQNMMLSSNEDKKGMCKL"
gene complement(616211..618241)
/gene="ASI3"
/locus_tag="YNL008C"
/db_xref="GeneID:855724"
mRNA complement(616211..618241)
/gene="ASI3"
/locus_tag="YNL008C"
/product="putative ubiquitin-protein ligase ASI3"
/transcript_id="NM_001182847.2"
/db_xref="GI:330443712"
/db_xref="GeneID:855724"
CDS complement(616211..618241)
/gene="ASI3"
/locus_tag="YNL008C"
/note="Putative integral membrane E3 ubiquitin ligase;
acts with Asi1p and Asi2p to ensure the fidelity of
SPS-sensor signalling by maintaining the dormant repressed
state of gene expression in the absence of inducing
signals; ASI3 has a paralog, ASI1, that arose from the
whole genome duplication"
/codon_start=1
/product="putative ubiquitin-protein ligase ASI3"
/protein_id="NP_014390.2"
/db_xref="GI:330443713"
/db_xref="SGD:S000004953"
/db_xref="GeneID:855724"
/translation="MSTNILQHVKQLLHNRDVFSFFHNKTGNLNYLDNTTQKPEVFVS
PNSTIVSAPTLDSFQALMEKGNFTTLQLAKVGIRMFFSYSVSKYAVLCFSTAIILNRL
TVMSSLRSNSTNIRLPLWSKTLLHLVATLSLVKALLQILSQFGLMHELHVSDTDFYAL
SVYLFVALSDCIEIFISSTTNVPSLICSDFSIWGLSLNLYIISKMPAGQQHIGDNVEL
LGAVFHRLVIHLVELFHIRAYRLCGEVILNAGFFTAFVTRTYLNGLDFINICLIHNYF
PGFFYISTILLASIGIFLKALFTSNPFRSLYSRYKNLEKWWRSNNYNGEEEFNEIALS
LCLLLTSNDYKIFKKSDNVKSVDEVAAFSNSYVVSGHLNQLQSTPEDLLSRKEMTTDS
QLPGFARTYLGLFELVRTIILTYSRLLKNLLWSKNFESSIDKKPRVGKRKKRDLNKYV
TEKNYKKFLYKPDVKELNIESDLRSLELLLPEDDSSKDYFPPRKIDESVSDEEFDSDM
ESQLIIDEEKELTHLSSNAVDSDDLEEIAWNISMWSILNYEMDVHNKVNGPLTRSQYG
KRNPQGVLVDVVIERLLHHTNSRYMYKRLNMKDDDKLEFKFDFAFDSCDEVEEMDLSC
LICKVNKRNIVTWPCRCLALCDDCRISLGYKGFATCVSCDSEVKGYSKLNIV"
rep_origin 616311..617125
/note="ARS1425;
Putative replication origin, identified in multiple array
studies, not yet confirmed by plasmid-based assay"
/db_xref="SGD:S000130144"
gene complement(618507..619565)
/gene="SIS1"
/locus_tag="YNL007C"
/db_xref="GeneID:855725"
mRNA complement(618507..619565)
/gene="SIS1"
/locus_tag="YNL007C"
/product="Sis1p"
/transcript_id="NM_001182846.1"
/db_xref="GI:296147757"
/db_xref="GeneID:855725"
CDS complement(618507..619565)
/gene="SIS1"
/locus_tag="YNL007C"
/note="Type II HSP40 co-chaperone that interacts with the
HSP70 protein Ssa1p; not functionally redundant with Ydj1p
due to due to substrate specificity; has similarity to
bacterial DnaJ proteins; protein abundance increases in
response to DNA replication stress"
/codon_start=1
/product="Sis1p"
/protein_id="NP_014391.1"
/db_xref="GI:6324321"
/db_xref="SGD:S000004952"
/db_xref="GeneID:855725"
/translation="MVKETKLYDLLGVSPSANEQELKKGYRKAALKYHPDKPTGDTEK
FKEISEAFEILNDPQKREIYDQYGLEAARSGGPSFGPGGPGGAGGAGGFPGGAGGFSG
GHAFSNEDAFNIFSQFFGGSSPFGGADDSGFSFSSYPSGGGAGMGGMPGGMGGMHGGM
GGMPGGFRSASSSPTYPEEETVQVNLPVSLEDLFVGKKKSFKIGRKGPHGASEKTQID
IQLKPGWKAGTKITYKNQGDYNPQTGRRKTLQFVIQEKSHPNFKRDGDDLIYTLPLSF
KESLLGFSKTIQTIDGRTLPLSRVQPVQPSQTSTYPGQGMPTPKNPSQRGNLIVKYKV
DYPISLNDAQKRAIDENF"
gene 620067..620978
/gene="LST8"
/locus_tag="YNL006W"
/db_xref="GeneID:855726"
mRNA 620067..620978
/gene="LST8"
/locus_tag="YNL006W"
/product="Lst8p"
/transcript_id="NM_001182845.3"
/db_xref="GI:398365488"
/db_xref="GeneID:855726"
CDS 620067..620978
/gene="LST8"
/locus_tag="YNL006W"
/note="Protein required for the transport of amino acid
permease Gap1p from the Golgi to the cell surface;
component of the TOR signaling pathway; associates with
both Tor1p and Tor2p; contains a WD-repeat"
/codon_start=1
/product="Lst8p"
/protein_id="NP_014392.3"
/db_xref="GI:398365489"
/db_xref="SGD:S000004951"
/db_xref="GeneID:855726"
/translation="MSVILVSAGYDHTIRFWEALTGVCSRTIQHSDSQVNRLEITNDK
KLLATAGHQNVRLYDIRTTNPNPVASFEGHRGNVTSVSFQQDNRWMVTSSEDGTIKVW
DVRSPSIPRNYKHNAPVNEVVIHPNQGELISCDRDGNIRIWDLGENQCTHQLTPEDDT
SLQSLSMASDGSMLAAANTKGNCYVWEMPNHTDASHLKPVTKFRAHSTYITRILLSSD
VKHLATCSADHTARVWSIDDDFKLETTLDGHQRWVWDCAFSADSAYLVTASSDHYVRL
WDLSTREIVRQYGGHHKGAVCVALNDV"
gene complement(621313..622428)
/gene="MRP7"
/locus_tag="YNL005C"
/db_xref="GeneID:855727"
mRNA complement(621313..622428)
/gene="MRP7"
/locus_tag="YNL005C"
/product="mitochondrial 54S ribosomal protein YmL2"
/transcript_id="NM_001182844.1"
/db_xref="GI:296147759"
/db_xref="GeneID:855727"
CDS complement(621313..622428)
/gene="MRP7"
/locus_tag="YNL005C"
/note="Mitochondrial ribosomal protein of the large
subunit"
/codon_start=1
/product="mitochondrial 54S ribosomal protein YmL2"
/protein_id="NP_014393.1"
/db_xref="GI:6324323"
/db_xref="SGD:S000004950"
/db_xref="GeneID:855727"
/translation="MWNPILLDTSSFSFQKHVSGVFLQVRNATKRAAGSRTSMKDSAG
RRLGPKKYEGQDVSTGEIIMRQRGTKFYPGENVGIGKDHSIFALEPGVVRYYLDPFHP
KRKFIGVALRRDLKLPSPHFEPTVRRFGRFELTNKRAAYKEENSISRKDYLAKPNILK
QLEVRESKRKELQDKLSKVLRDELKLDIKDIELATSYLIRVRASLKNGYPIEDARFNS
RYYLKEEERLKARRESWTNEKLSESLSKIDECSDLLNSSTSFNNKLELHQYISEQEKQ
ALKAKLLEDLEKSQHLETKKDKNYIKALFKDACNFLTLSEEVHLRRKYLKSVFPETDS
TVETKSGKKSIVSRRFDYTKNKVEVIARSRRAFLSKL"
gene 622915..624621
/gene="HRB1"
/locus_tag="YNL004W"
/gene_synonym="TOM34"
/db_xref="GeneID:855728"
mRNA join(622915..622944,623287..624621)
/gene="HRB1"
/locus_tag="YNL004W"
/gene_synonym="TOM34"
/product="Hrb1p"
/transcript_id="NM_001182843.1"
/db_xref="GI:296147760"
/db_xref="GeneID:855728"
CDS join(622915..622944,623287..624621)
/gene="HRB1"
/locus_tag="YNL004W"
/gene_synonym="TOM34"
/note="Poly(A+) RNA-binding protein, involved in the
export of mRNAs from the nucleus to the cytoplasm; similar
to Gbp2p and Npl3p"
/codon_start=1
/product="Hrb1p"
/protein_id="NP_014394.2"
/db_xref="GI:154199622"
/db_xref="SGD:S000004949"
/db_xref="GeneID:855728"
/translation="MSDQERGSENNNRSRSRSRSPVRRRMSDDHGYERDNHLSRRSGN
YNGRRKFADTYRGSRDRGEYRGGRERSDYRERERFNNRDNPRSRDRYDDRRRGRDVTG
RYGNRRDDYPRSFRSRHNTRDDSRRGGFGSSGARGDYGPLLARELDSTYEEKVNRNYS
NSIFVGNLTYDSTPEDLTEFFSQIGKVVRADIITSRGHHRGMGTVEFTNSDDVDRAIR
QYDGAFFMDRKIFVRQDNPPPSNNIKERKALDRGELRHNRKTHEVIVKNLPASVNWQA
LKDIFKECGNVAHADVELDGDGVSTGSGTVSFYDIKDLHRAIEKYNGYSIEGNVLDVK
SKESVHNHSDGDDVDIPMDDSPVNEEARKFTENVVGGGERNRLIYCSNLPFSTAKSDL
YDLFETIGKVNNAELRYDSKGAPTGIAVVEYDNVDDADVCIERLNNYNYGGCDLDISY
AKRL"
gene complement(624975..625829)
/gene="PET8"
/locus_tag="YNL003C"
/gene_synonym="SAM5"
/db_xref="GeneID:855729"
mRNA complement(624975..625829)
/gene="PET8"
/locus_tag="YNL003C"
/gene_synonym="SAM5"
/product="Pet8p"
/transcript_id="NM_001182842.3"
/db_xref="GI:398365518"
/db_xref="GeneID:855729"
CDS complement(624975..625829)
/gene="PET8"
/locus_tag="YNL003C"
/gene_synonym="SAM5"
/note="S-adenosylmethionine transporter of the
mitochondrial inner membrane, member of the mitochondrial
carrier family; required for biotin biosynthesis and
respiratory growth"
/codon_start=1
/product="Pet8p"
/protein_id="NP_014395.3"
/db_xref="GI:398365519"
/db_xref="SGD:S000004948"
/db_xref="GeneID:855729"
/translation="MNTFFLSLLSGAAAGTSTDLVFFPIDTIKTRLQAKGGFFANGGY
KGIYRGLGSAVVASAPGASLFFISYDYMKVKSRPYISKLYSQGSEQLIDTTTHMLSSS
IGEICACLVRVPAEVVKQRTQVHSTNSSWQTLQSILRNDNKEGLRKNLYRGWSTTIMR
EIPFTCIQFPLYEYLKKTWAKANGQSQVEPWKGAICGSIAGGIAAATTTPLDFLKTRL
MLNKTTASLGSVIIRIYREEGPAVFFSGVGPRTMWISAGGAIFLGMYETVHSLLSKSF
PTAGEMRA"
gene complement(626174..627142)
/gene="RLP7"
/locus_tag="YNL002C"
/gene_synonym="RPL7"
/db_xref="GeneID:855730"
mRNA complement(626174..627142)
/gene="RLP7"
/locus_tag="YNL002C"
/gene_synonym="RPL7"
/product="Rlp7p"
/transcript_id="NM_001182841.3"
/db_xref="GI:398365526"
/db_xref="GeneID:855730"
CDS complement(626174..627142)
/gene="RLP7"
/locus_tag="YNL002C"
/gene_synonym="RPL7"
/note="Nucleolar protein with similarity to large
ribosomal subunit L7 proteins; constituent of 66S
pre-ribosomal particles; plays an essential role in
processing of precursors to the large ribosomal subunit
RNAs"
/codon_start=1
/product="Rlp7p"
/protein_id="NP_014396.3"
/db_xref="GI:398365527"
/db_xref="SGD:S000004947"
/db_xref="GeneID:855730"
/translation="MSSTQDSKAQTLNSNPEILLRKRRNADRTRIERQELAKKKREEQ
IKKKRSNKNKFVRAESIVAKTLATSREKERIKRVSILEDKKAKNETQHIASGKDFILK
ITEKANGAEENSVDLEETEEEEDDGLIREKTTYDGKPALLFIVRVRGPLAVNIPNKAF
KILSLLRLVETNTGVFVKLTKNVYPLLKVIAPYVVIGKPSLSSIRSLIQKRGRIIYKG
ENEAEPHEIVLNDNNIVEEQLGDHGIICVEDIIHEIATMGESFSVCNFFLQPFKLNRE
VSGFGSLNRLRKIKQREAESRTRQFSNAATAPVIEVDIDSLLAKLN"
gene 627456..628616
/gene="DOM34"
/locus_tag="YNL001W"
/db_xref="GeneID:855731"
mRNA 627456..628616
/gene="DOM34"
/locus_tag="YNL001W"
/product="Dom34p"
/transcript_id="NM_001182840.1"
/db_xref="GI:296147763"
/db_xref="GeneID:855731"
CDS 627456..628616
/gene="DOM34"
/locus_tag="YNL001W"
/note="Protein that facilitates ribosomal subunit
dissociation; acts when translation is stalled, with
binding partner Hbs1p; required for RNA cleavage in no-go
decay, but reports conflict on endonuclease activity;
Pelota ortholog; protein abundance increases in response
to DNA replication stress"
/codon_start=1
/product="Dom34p"
/protein_id="NP_014397.1"
/db_xref="GI:6324327"
/db_xref="SGD:S000004946"
/db_xref="GeneID:855731"
/translation="MKVISLKKDSFNKGGAVITLLPEDKEDLFTVYQIVDKDDELIFK
KKFTSKLDEAGKKKSTDLVKLKIKVISEDFDMKDEYLKYKGVTVTDESGASNVDIPVG
KYLSFTLDYVYPFTIIKQNFNKFMQKLLNEACNIEYKSDTAAVVLQEGIAHVCLVTSS
STILKQKIEYSMPKKKRTTDVLKFDEKTEKFYKAIYSAMKKDLNFDKLKTIILCSPGF
YAKILMDKIFQYAEEEHNKKILDNKGMFFIAHCSTGYLQGINEVLKNPLYASKLQDTK
YSKEIMVMDEFLLHLNKDDDKAWYGEKEVVKAAEYGAISYLLLTDKVLHSDNIAQREE
YLKLMDSVESNGGKALVLSTLHSLGEELDQLTGIACILKYPLPDLDEDDGEE"
centromere 628758..628875
/note="CEN14; Chromosome XIV centromere"
/db_xref="SGD:S000006475"
centromere 628758..628767
/note="CEN14_CDEI of CEN14"
centromere 628768..628850
/note="CEN14_CDEII of CEN14"
centromere 628851..628875
/note="CEN14_CDEIII of CEN14"
gene complement(629622..631061)
/gene="CIT1"
/locus_tag="YNR001C"
/gene_synonym="LYS6"
/db_xref="GeneID:855732"
mRNA complement(629622..631061)
/gene="CIT1"
/locus_tag="YNR001C"
/gene_synonym="LYS6"
/product="citrate (Si)-synthase CIT1"
/transcript_id="NM_001183178.1"
/db_xref="GI:296147764"
/db_xref="GeneID:855732"
CDS complement(629622..631061)
/gene="CIT1"
/locus_tag="YNR001C"
/gene_synonym="LYS6"
/EC_number="2.3.3.1"
/note="Citrate synthase; catalyzes the condensation of
acetyl coenzyme A and oxaloacetate to form citrate; the
rate-limiting enzyme of the TCA cycle; nuclear encoded
mitochondrial protein; CIT1 has a paralog, CIT2, that
arose from the whole genome duplication"
/codon_start=1
/product="citrate (Si)-synthase CIT1"
/protein_id="NP_014398.1"
/db_xref="GI:6324328"
/db_xref="SGD:S000005284"
/db_xref="GeneID:855732"
/translation="MSAILSTTSKSFLSRGSTRQCQNMQKALFALLNARHYSSASEQT
LKERFAEIIPAKAEEIKKFKKEHGKTVIGEVLLEQAYGGMRGIKGLVWEGSVLDPEEG
IRFRGRTIPEIQRELPKAEGSTEPLPEALFWLLLTGEIPTDAQVKALSADLAARSEIP
EHVIQLLDSLPKDLHPMAQFSIAVTALESESKFAKAYAQGVSKKEYWSYTFEDSLDLL
GKLPVIASKIYRNVFKDGKITSTDPNADYGKNLAQLLGYENKDFIDLMRLYLTIHSDH
EGGNVSAHTTHLVGSALSSPYLSLAAGLNGLAGPLHGRANQEVLEWLFKLREEVKGDY
SKETIEKYLWDTLNAGRVVPGYGHAVLRKTDPRYTAQREFALKHFPDYELFKLVSTIY
EVAPGVLTKHGKTKNPWPNVDSHSGVLLQYYGLTEASFYTVLFGVARAIGVLPQLIID
RAVGAPIERPKSFSTEKYKELVKKIESKN"
gene complement(631846..631917)
/gene="SUF10"
/locus_tag="tP(AGG)N"
/db_xref="GeneID:855734"
tRNA complement(631846..631917)
/gene="SUF10"
/locus_tag="tP(AGG)N"
/product="tRNA-Pro"
/note="Proline tRNA (tRNA-Pro), predicted by tRNAscan-SE
analysis; can mutate to suppress +1 frameshift mutations
in proline codons"
/db_xref="SGD:S000006679"
/db_xref="GeneID:855734"
LTR complement(631998..632114)
/note="Ty1 LTR"
/db_xref="SGD:S000007143"
LTR complement(632119..632489)
/note="Ty4 LTR"
/db_xref="SGD:S000007146"
gene 632599..632672
/locus_tag="tN(GUU)N2"
/db_xref="GeneID:855735"
tRNA 632599..632672
/locus_tag="tN(GUU)N2"
/product="tRNA-Asn"
/note="Asparagine tRNA (tRNA-Asn), predicted by
tRNAscan-SE analysis"
/db_xref="SGD:S000006674"
/db_xref="GeneID:855735"
gene complement(633008..633856)
/gene="ATO2"
/locus_tag="YNR002C"
/gene_synonym="FUN34"
/db_xref="GeneID:855736"
mRNA complement(633008..633856)
/gene="ATO2"
/locus_tag="YNR002C"
/gene_synonym="FUN34"
/product="Ato2p"
/transcript_id="NM_001183179.3"
/db_xref="GI:398365548"
/db_xref="GeneID:855736"
CDS complement(633008..633856)
/gene="ATO2"
/locus_tag="YNR002C"
/gene_synonym="FUN34"
/note="Putative transmembrane protein involved in export
of ammonia; ammonia is a starvation signal that promotes
cell death in aging colonies; phosphorylated in
mitochondria; member of the TC 9.B.33 YaaH family; homolog
of Y. lipolytica Gpr1p; ATO2 has a paralog, ADY2, that
arose from the whole genome duplication"
/codon_start=1
/product="Ato2p"
/protein_id="NP_014399.3"
/db_xref="GI:398365549"
/db_xref="SGD:S000005285"
/db_xref="GeneID:855736"
/translation="MSDREQSSGNTAFENPKALDSSEGEFISENNDQSRHSQESICKI
YTAGKNNEYIYIGRQKFLRDDLFEAFGGTLNPGLAPAPVHKFANPAPLGLSGFALTTF
VLSMFNARAQGITIPNVVVGCAMFYGGLVQLIAGIWEIALENTFGGTALCSFGGFWLS
FGAIYIPWFGILDAYKDKESDLGNALGFYLLGWALFTFGLSVCTMKSTIMFFALFFLL
AVTFLLLSIANFTGEVGVTRAGGVLGVIVAFIAWYNAYAGIATRQNSYIMVHPFALPS
NDKVFF"
gene complement(634344..635297)
/gene="RPC34"
/locus_tag="YNR003C"
/db_xref="GeneID:855737"
mRNA complement(634344..635297)
/gene="RPC34"
/locus_tag="YNR003C"
/product="Rpc34p"
/transcript_id="NM_001183180.1"
/db_xref="GI:296147766"
/db_xref="GeneID:855737"
CDS complement(634344..635297)
/gene="RPC34"
/locus_tag="YNR003C"
/note="RNA polymerase III subunit C34; interacts with
TFIIIB70 and is a key determinant in pol III recruitment
by the preinitiation complex"
/codon_start=1
/product="Rpc34p"
/protein_id="NP_014400.1"
/db_xref="GI:6324330"
/db_xref="SGD:S000005286"
/db_xref="GeneID:855737"
/translation="MSGMIENGLQLSDNAKTLHSQMMSKGIGALFTQQELQKQMGIGS
LTDLMSIVQELLDKNLIKLVKQNDELKFQGVLESEAQKKATMSAEEALVYSYIEASGR
EGIWSKTIKARTNLHQHVVLKCLKSLESQRYVKSVKSVKFPTRKIYMLYSLQPSVDIT
GGPWFTDGELDIEFINSLLTIVWRFISENTFPNGFKNFENGPKKNVFYAPNVKNYSTT
QEILEFITAAQVANVELTPSNIRSLCEVLVYDDKLEKVTHDCYRVTLESILQMNQGEG
EPEAGNKALEDEEEFSIFNYFKMFPASKHDKEVVYFDEWTI"
rep_origin 635664..635904
/note="ARS1426;
Autonomously Replicating Sequence"
/db_xref="SGD:S000118392"
gene 635943..636383
/gene="SWM2"
/locus_tag="YNR004W"
/db_xref="GeneID:855738"
mRNA 635943..636383
/gene="SWM2"
/locus_tag="YNR004W"
/product="Swm2p"
/transcript_id="NM_001183181.1"
/db_xref="GI:296147767"
/db_xref="GeneID:855738"
CDS 635943..636383
/gene="SWM2"
/locus_tag="YNR004W"
/note="hypothetical protein; haploid disruptant exhibits
cold-sensitive growth and elongated buds"
/codon_start=1
/product="Swm2p"
/protein_id="NP_014401.1"
/db_xref="GI:6324331"
/db_xref="SGD:S000005287"
/db_xref="GeneID:855738"
/translation="MIDLYNYSNLEGLLDGLTDLNRIPKEYSAVLEPYFQNIARNAHL
KSRALKICRSNFHKWNEEGAKTVNPEIIRRCLNLWYVLKGKEYKKLKDPPPADNIIKD
EIDVSYVKNLNVVRLEFDEFGKLISNPLENLILEEVEVNDFIQE"
gene 636986..638854
/gene="VPS27"
/locus_tag="YNR006W"
/gene_synonym="DID7; GRD11; SSV17; VPL23; VPT27"
/db_xref="GeneID:855739"
mRNA 636986..638854
/gene="VPS27"
/locus_tag="YNR006W"
/gene_synonym="DID7; GRD11; SSV17; VPL23; VPT27"
/product="Vps27p"
/transcript_id="NM_001183183.3"
/db_xref="GI:398365556"
/db_xref="GeneID:855739"
CDS 636986..638854
/gene="VPS27"
/locus_tag="YNR006W"
/gene_synonym="DID7; GRD11; SSV17; VPL23; VPT27"
/note="Endosomal protein that forms a complex with Hse1p;
required for recycling Golgi proteins, forming lumenal
membranes and sorting ubiquitinated proteins destined for
degradation; has Ubiquitin Interaction Motifs which bind
ubiquitin (Ubi4p)"
/codon_start=1
/product="Vps27p"
/protein_id="NP_014403.3"
/db_xref="GI:398365557"
/db_xref="SGD:S000005289"
/db_xref="GeneID:855739"
/translation="MSVSTPSELDALIEQATSESIPNGDLDLPIALEISDVLRSRRVN
PKDSMRCIKKRILNTADNPNTQLSSWKLTNICVKNGGTPFIKEICSREFMDTMEHVIL
REDSNEELSELVKTILYELYVAFKNDSQLNYVAKVYDKLISRGIKFPEKLTLSNSPTA
MFDSKTPADWIDSDACMICSKKFSLLNRKHHCRSCGGVFCQEHSSNSIPLPDLGIYEP
VRVCDSCFEDYDLKRHDDSKKSKKHRHKRKKDRDYSTPEDEEELIRKAIELSLKESRN
SASSEPIVPVVESKNEVKRQEIEEEEDPDLKAAIQESLREAEEAKLRSERQKASRQMQ
PQQPSPQPQPIHSVDLSDEEKDSIYMFASLVEKMKSRPLNEILEDSKLQNLAQRVFAS
KARLNYALNDKAQKYNTLIEMNGKISEIMNIYDRLLEQQLQSINLSQQYTLPQVPSDP
YNYLTENVQNPAESYQTPPLQQLSSHQYKPQQDVSRQQSVKANSSPTTNIDHLKTIDV
TPHAQQKPQSHVELAPSDPPYPKEEAEDEGTQAVQDEESSTQESRERPYPVETENGET
SINKRPQGITRYDFPTVPARKFVQPESTVPLPASSSEIPIKEERPPSPQEELLIEL"
gene complement(639182..640114)
/gene="ATG3"
/locus_tag="YNR007C"
/gene_synonym="APG3; AUT1"
/db_xref="GeneID:855741"
mRNA complement(639182..640114)
/gene="ATG3"
/locus_tag="YNR007C"
/gene_synonym="APG3; AUT1"
/product="Atg3p"
/transcript_id="NM_001183184.3"
/db_xref="GI:398365566"
/db_xref="GeneID:855741"
CDS complement(639182..640114)
/gene="ATG3"
/locus_tag="YNR007C"
/gene_synonym="APG3; AUT1"
/note="E2-like enzyme involved in autophagy and the
cytoplasm-to-vacuole targeting (Cvt) pathway; plays a role
in formation of Atg8p-phosphatidylethanolamine conjugates,
which are involved in membrane dynamics during autophagy
and Cvt"
/codon_start=1
/product="Atg3p"
/protein_id="NP_014404.3"
/db_xref="GI:398365567"
/db_xref="SGD:S000005290"
/db_xref="GeneID:855741"
/translation="MIRSTLSSWREYLTPITHKSTFLTTGQITPEEFVQAGDYLCHMF
PTWKWNEESSDISYRDFLPKNKQFLIIRKVPCDKRAEQCVEVEGPDVIMKGFAEDGDE
DDVLEYIGSETEHVQSTPAGGTKDSSIDDIDELIQDMEIKEEDENDDTEEFNAKGGLA
KDMAQERYYDLYIAYSTSYRVPKMYIVGFNSNGSPLSPEQMFEDISADYRTKTATIEK
LPFYKNSVLSVSIHPCKHANVMKILLDKVRVVRQRRRKELQEEQELDGVGDWEDLQDD
IDDSLRVDQYLIVFLKFITSVTPSIQHDYTMEGW"
gene 640396..642381
/gene="LRO1"
/locus_tag="YNR008W"
/db_xref="GeneID:855742"
mRNA 640396..642381
/gene="LRO1"
/locus_tag="YNR008W"
/product="phospholipid:diacylglycerol acyltransferase"
/transcript_id="NM_001183185.1"
/db_xref="GI:296147770"
/db_xref="GeneID:855742"
CDS 640396..642381
/gene="LRO1"
/locus_tag="YNR008W"
/EC_number="2.3.1.158"
/note="Acyltransferase that catalyzes diacylglycerol
esterification; one of several acyltransferases that
contribute to triglyceride synthesis; putative homolog of
human lecithin cholesterol acyltransferase"
/codon_start=1
/product="phospholipid:diacylglycerol acyltransferase"
/protein_id="NP_014405.1"
/db_xref="GI:6324335"
/db_xref="SGD:S000005291"
/db_xref="GeneID:855742"
/translation="MGTLFRRNVQNQKSDSDENNKGGSVHNKRESRNHIHHQQGLGHK
RRRGISGSAKRNERGKDFDRKRDGNGRKRWRDSRRLIFILGAFLGVLLPFSFGAYHVH
NSDSDLFDNFVNFDSLKVYLDDWKDVLPQGISSFIDDIQAGNYSTSSLDDLSENFAVG
KQLLRDYNIEAKHPVVMVPGVISTGIESWGVIGDDECDSSAHFRKRLWGSFYMLRTMV
MDKVCWLKHVMLDPETGLDPPNFTLRAAQGFESTDYFIAGYWIWNKVFQNLGVIGYEP
NKMTSAAYDWRLAYLDLERRDRYFTKLKEQIELFHQLSGEKVCLIGHSMGSQIIFYFM
KWVEAEGPLYGNGGRGWVNEHIDSFINAAGTLLGAPKAVPALISGEMKDTIQLNTLAM
YGLEKFFSRIERVKMLQTWGGIPSMLPKGEEVIWGDMKSSSEDALNNNTDTYGNFIRF
ERNTSDAFNKNLTMKDAINMTLSISPEWLQRRVHEQYSFGYSKNEEELRKNELHHKHW
SNPMEVPLPEAPHMKIYCIYGVNNPTERAYVYKEEDDSSALNLTIDYESKQPVFLTEG
DGTVPLVAHSMCHKWAQGASPYNPAGINVTIVEMKHQPDRFDIRGGAKSAEHVDILGS
AELNDYILKIASGNGDLVEPRQLSNLSQWVSQMPFPM"
gene 642690..643439
/gene="NRM1"
/locus_tag="YNR009W"
/db_xref="GeneID:855743"
mRNA 642690..643439
/gene="NRM1"
/locus_tag="YNR009W"
/product="Nrm1p"
/transcript_id="NM_001183186.1"
/db_xref="GI:296147771"
/db_xref="GeneID:855743"
CDS 642690..643439
/gene="NRM1"
/locus_tag="YNR009W"
/note="Transcriptional co-repressor of MBF (MCB binding
factor)-regulated gene expression; Nrm1p associates stably
with promoters via MBF to repress transcription upon exit
from G1 phase"
/codon_start=1
/product="Nrm1p"
/protein_id="NP_014406.1"
/db_xref="GI:6324336"
/db_xref="SGD:S000005292"
/db_xref="GeneID:855743"
/translation="MSIMKQRLPLGEFSSSKINKLAIANIADASEPRNHGENNVGTVC
LPSIKSLMVSPEVYENTKSLPVPLMRSSGGGMACASKSSCQDGISTKTTSRDYSELSK
KLQIRLQFAYYKYKTKQTDKNFTDLKSKHSITRPSKVATHSKSEPLTRRRKLVLSQGH
YKTPARSKIKTPSSICSHDNTSSFTSFRGVSESSSTTADMNVADTTTPIRNNINTKHS
NSHNRTLYQRQETPTSIKAAKSLIHLFTSNQ"
gene 643744..644193
/gene="CSE2"
/locus_tag="YNR010W"
/gene_synonym="MED9"
/db_xref="GeneID:855744"
mRNA 643744..644193
/gene="CSE2"
/locus_tag="YNR010W"
/gene_synonym="MED9"
/product="Cse2p"
/transcript_id="NM_001183187.3"
/db_xref="GI:398365586"
/db_xref="GeneID:855744"
CDS 643744..644193
/gene="CSE2"
/locus_tag="YNR010W"
/gene_synonym="MED9"
/note="Subunit of the RNA polymerase II mediator complex;
associates with core polymerase subunits to form the RNA
polymerase II holoenzyme; component of the Middle domain
of mediator; required for regulation of RNA polymerase II
activity"
/codon_start=1
/product="Cse2p"
/protein_id="NP_014407.3"
/db_xref="GI:398365587"
/db_xref="SGD:S000005293"
/db_xref="GeneID:855744"
/translation="MNLQNNVLNQIHQILLPTNPTLDKPNAEATKEEFSSAENRDEKD
YLTNQQPKNLSTPSTSSNGEFIPHIFYSLHQIRKDPNNLSNQLETLTGSIRHRLKLCK
SLISENEDTKDLLSKSPSEWQDIIHQREQELQIKRDVLDDLYRKLQR"
gene complement(644320..646950)
/gene="PRP2"
/locus_tag="YNR011C"
/gene_synonym="RNA2"
/db_xref="GeneID:855745"
mRNA complement(644320..646950)
/gene="PRP2"
/locus_tag="YNR011C"
/gene_synonym="RNA2"
/product="DEAH-box RNA-dependent ATPase PRP2"
/transcript_id="NM_001183188.1"
/db_xref="GI:296147773"
/db_xref="GeneID:855745"
CDS complement(644320..646950)
/gene="PRP2"
/locus_tag="YNR011C"
/gene_synonym="RNA2"
/EC_number="3.6.1.-"
/note="RNA-dependent ATPase in the DEAH-box family,
required for activation of the spliceosome before the
first transesterification step in RNA splicing;
orthologous to human protein DHX16"
/codon_start=1
/product="DEAH-box RNA-dependent ATPase PRP2"
/protein_id="NP_014408.1"
/db_xref="GI:6324338"
/db_xref="SGD:S000005294"
/db_xref="GeneID:855745"
/translation="MSSITSETGKRRVKRTYEVTRQNDNAVRIEPSSLGEEEDKEAKD
KNSALQLKRSRYDPNKVFSNTNQGPEKNNLKGEQLGSQKKSSKYDEKITSNNELTTKK
GLLGDSENETKYASSNSKFNVEVTHKIKNAKEIDKINRQRMWEEQQLRNAMAGQSDHP
DDITLEGSDKYDYVFDTDAMIDYTNEEDDLLPEEKLQYEARLAQALETEEKRILTIQE
ARKLLPVHQYKDELLQEIKKNQVLIIMGETGSGKTTQLPQYLVEDGFTDQGKLQIAIT
QPRRVAATSVAARVADEMNVVLGKEVGYQIRFEDKTTPNKTVLKYMTDGMLLREFLTD
SKLSKYSCIMIDEAHERTLATDILIGLLKDILPQRPTLKLLISSATMNAKKFSEFFDN
CPIFNVPGRRYPVDIHYTLQPEANYIHAAITTIFQIHTTQSLPGDILVFLTGQEEIER
TKTKLEEIMSKLGSRTKQMIITPIYANLPQEQQLKIFQPTPENCRKVVLATNIAETSL
TIDGIRYVIDPGFVKENSYVPSTGMTQLLTVPCSRASVDQRAGRAGRVGPGKCFRIFT
KWSYLHELELMPKPEITRTNLSNTVLLLLSLGVTDLIKFPLMDKPSIPTLRKSLENLY
ILGALNSKGTITRLGKMMCEFPCEPEFAKVLYTAATHEQCQGVLEECLTIVSMLHETP
SLFIGQKRDAAASVLSEVESDHILYLEIFNQWRNSKFSRSWCQDHKIQFKTMLRVRNI
RNQLFRCSEKVGLVEKNDQARMKIGNIAGYINARITRCFISGFPMNIVQLGPTGYQTM
GRSSGGLNVSVHPTSILFVNHKEKAQRPSKYVLYQQLMLTSKEFIRDCLVIPKEEWLI
DMVPQIFKDLIDDKTNRGRR"
gene 647432..648937
/gene="URK1"
/locus_tag="YNR012W"
/db_xref="GeneID:855746"
mRNA 647432..648937
/gene="URK1"
/locus_tag="YNR012W"
/product="uridine kinase URK1"
/transcript_id="NM_001183189.1"
/db_xref="GI:296147774"
/db_xref="GeneID:855746"
CDS 647432..648937
/gene="URK1"
/locus_tag="YNR012W"
/EC_number="2.7.1.74"
/EC_number="2.7.1.48"
/note="Uridine/cytidine kinase, component of the
pyrimidine ribonucleotide salvage pathway that converts
uridine into UMP and cytidine into CMP; involved in the
pyrimidine deoxyribonucleotide salvage pathway, converting
deoxycytidine into dCMP"
/codon_start=1
/product="uridine kinase URK1"
/protein_id="NP_014409.1"
/db_xref="GI:6324339"
/db_xref="SGD:S000005295"
/db_xref="GeneID:855746"
/translation="MSHRIAPSKERSSSFISILDDETRDTLKANAVMDGEVDVKKTKG
KSSRYIPPWTTPYIIGIGGASGSGKTSVAAKIVSSINVPWTVLISLDNFYNPLGPEDR
ARAFKNEYDFDEPNAINLDLAYKCILNLKEGKRTNIPVYSFVHHNRVPDKNIVIYGAS
VVVIEGIYALYDRRLLDLMDLKIYVDADLDVCLARRLSRDIVSRGRDLDGCIQQWEKF
VKPNAVKFVKPTMKNADAIIPSMSDNATAVNLIINHIKSKLELKSNEHLRELIKLGSS
PSQDVLNRNIIHELPPTNQVLSLHTMLLNKNLNCADFVFYFDRLATILLSWALDDIPV
AHTNIITPGEHTMENVIACQFDQVTAVNIIRSGDCFMKSLRKTIPNITIGKLLIQSDS
QTGEPQLHCEFLPPNIEKFGKVFLMEGQIISGAAMIMAIQVLLDHGIDLEKISVVVYL
ATEVGIRRILNAFDNKVNIFAGMIISREKLQNHQYKWALTRFFDSKYFGCD"
gene complement(649028..651712)
/gene="PHO91"
/locus_tag="YNR013C"
/db_xref="GeneID:855747"
mRNA complement(649028..651712)
/gene="PHO91"
/locus_tag="YNR013C"
/product="Pho91p"
/transcript_id="NM_001183190.3"
/db_xref="GI:398365614"
/db_xref="GeneID:855747"
CDS complement(649028..651712)
/gene="PHO91"
/locus_tag="YNR013C"
/note="Low-affinity phosphate transporter of the vacuolar
membrane; deletion of pho84, pho87, pho89, pho90, and
pho91 causes synthetic lethality; transcription
independent of Pi and Pho4p activity; overexpression
results in vigorous growth"
/codon_start=1
/product="Pho91p"
/protein_id="NP_014410.3"
/db_xref="GI:398365615"
/db_xref="SGD:S000005296"
/db_xref="GeneID:855747"
/translation="MKFSHSLQFNSVPEWSTKYLAYSQLKKLIYSLQKDKLYSNNKHH
VVEPHDANDENLPLLADASPDDQFYISKFVAALNQELKKIDKFYISQETGLIANYNEL
KDDVMELENTNKATQLFNQQQQHQLQSVARNRKSKSQQRQRRFSSVSSTDSNPSLTDM
SIDSAPVIHTQVSNTTNNGNSMQNLASASVSLSNSNPVYLSPFTQHRLSLKKRLISIY
TQLSELKDFIELNQTGFSKICKKFDKSLNTNLKQNYLNYIKFHSHVFNPATINRIQHH
ITETILTYASLNKGTRRPSNTFNLDADRINNDENSSGNEEDEDGNRQEVLDFQDAERE
LSSHLRDHVVWERNTVWKDMMNLERKYQSAKTDNKKFSKLSSSQLRPNANITESMAMS
SGGAGIIAPSTDSLTFRELMHLPPKQWLQFIMGQTSLLKFLLITSCFIALLTFNLTPF
TQDSLQKNCFAILIYASLLWATETIPLFVTSLMIPLLIVVFPVIKDPITSQPMSPRDS
SQFILSTMWSSVIMLLLGGFTLAAALSKYNIAKVLSTHILASAGTNPHFILLTNMFVA
LFVSMWVSNVAAPVLCYSIVQPLLRTLPRNCSYAKALILGIALASNIGGMSSPIASPQ
NIFSIGIMDPSPSWAEWFMIALPVCFICVMAIWVLLIITFPPEPNVKILQLHPSRDPF
TLKQWFVTLVCIITIVLWCLSNQISGIFGEMGIISIIPIVVFFGTGLLTSDDFNNFMW
TIVVLAMGGTTLGKAVSSSGLLSTMAQLIKAQVEHEPIFIIVLIFGLVILVMATFVSH
TVAAMIIVPLMSEIGSNLPSGDHSRLLIVIAALLCSSAMGLPTSGFPNVTAISMIDEV
GDRYLTVGTFITRGVPASLLSYAAIVTVGYGILKVMGF"
gene 652465..653103
/locus_tag="YNR014W"
/db_xref="GeneID:855748"
mRNA 652465..653103
/locus_tag="YNR014W"
/product="hypothetical protein"
/transcript_id="NM_001183191.3"
/db_xref="GI:398365618"
/db_xref="GeneID:855748"
CDS 652465..653103
/locus_tag="YNR014W"
/note="hypothetical protein; expression is cell-cycle
regulated, Azf1p-dependent, and heat-inducible"
/codon_start=1
/product="hypothetical protein"
/protein_id="NP_014411.3"
/db_xref="GI:398365619"
/db_xref="SGD:S000005297"
/db_xref="GeneID:855748"
/translation="MSSTDIKPCAVNIPVSAHITFHYKSIADRSSSRSSSSSSCSSAT
SKACSPRGSSVGLPPALSTDNEIVETVLNVSAPVVADPTRPSLFKSNYTAASCLTSDP
TSPSLLPSSRRNSVLPASDFHQCAHHKNFQRRASEPQLPSFDNRSSSEMKRSVSYAQH
SMMFPISDQQEPQTSASPNDHSDPSCPCNRHHHRRNSVAVKFDKPLYERLET"
gene 653387..654541
/gene="SMM1"
/locus_tag="YNR015W"
/gene_synonym="DUS2"
/db_xref="GeneID:855749"
mRNA 653387..654541
/gene="SMM1"
/locus_tag="YNR015W"
/gene_synonym="DUS2"
/product="Smm1p"
/transcript_id="NM_001183192.1"
/db_xref="GI:296147777"
/db_xref="GeneID:855749"
CDS 653387..654541
/gene="SMM1"
/locus_tag="YNR015W"
/gene_synonym="DUS2"
/EC_number="1.-.-.-"
/note="Dihydrouridine synthase, member of a family of
dihydrouridine synthases including Dus1p, Smm1p, Dus3p,
and Dus4p; modifies uridine residues at position 20 of
cytoplasmic tRNAs"
/codon_start=1
/product="Smm1p"
/protein_id="NP_014412.1"
/db_xref="GI:6324342"
/db_xref="SGD:S000005298"
/db_xref="GeneID:855749"
/translation="MVTYAGKLVLAPMVRAGELPTRLMALAHGADLVWSPEIIDKKLI
QCVRKENTALQTVDYVVPSKVQTRPETLVFRTYPKLESSKLIFQIGSASPALATQAAL
KVINDVSGIDINAGCPKHFSIHSGMGSALLRTPDTLCLILKELVKNVGNPHSKPISVK
IRLLDTKQDTLQLVKRLCATGITNLTVHCRKTEMRNREQPITDYIAEIYEICQANNVS
LIVNGAIRDRSHFHDLQANHWKNTNIGGMIAECAERDPTVFDHTSKPSEDGPSWVVAC
REFIQWATKFDNHIGNTKYMLSRIVPGKSVFFQYFARCKSPEEVSFVLKQLNDDGSAQ
TDPSEYLENCRAQEKALKNANAIAKQKRKQTDHIGSDTKKQKVVPLPTDI"
gene complement(654673..661374)
/gene="ACC1"
/locus_tag="YNR016C"
/gene_synonym="ABP2; FAS3; MTR7"
/db_xref="GeneID:855750"
mRNA complement(654673..661374)
/gene="ACC1"
/locus_tag="YNR016C"
/gene_synonym="ABP2; FAS3; MTR7"
/product="acetyl-CoA carboxylase ACC1"
/transcript_id="NM_001183193.1"
/db_xref="GI:296147778"
/db_xref="GeneID:855750"
CDS complement(654673..661374)
/gene="ACC1"
/locus_tag="YNR016C"
/gene_synonym="ABP2; FAS3; MTR7"
/EC_number="6.4.1.2"
/EC_number="6.3.4.14"
/note="Acetyl-CoA carboxylase, biotin containing enzyme;
catalyzes the carboxylation of cytosolic acetyl-CoA to
form malonyl-CoA and regulates histone acetylation by
regulating the availablity of acetyl-CoA; required for de
novo biosynthesis of long-chain fatty acids"
/codon_start=1
/product="acetyl-CoA carboxylase ACC1"
/protein_id="NP_014413.1"
/db_xref="GI:6324343"
/db_xref="SGD:S000005299"
/db_xref="GeneID:855750"
/translation="MSEESLFESSPQKMEYEITNYSERHTELPGHFIGLNTVDKLEES
PLRDFVKSHGGHTVISKILIANNGIAAVKEIRSVRKWAYETFGDDRTVQFVAMATPED
LEANAEYIRMADQYIEVPGGTNNNNYANVDLIVDIAERADVDAVWAGWGHASENPLLP
EKLSQSKRKVIFIGPPGNAMRSLGDKISSTIVAQSAKVPCIPWSGTGVDTVHVDEKTG
LVSVDDDIYQKGCCTSPEDGLQKAKRIGFPVMIKASEGGGGKGIRQVEREEDFIALYH
QAANEIPGSPIFIMKLAGRARHLEVQLLADQYGTNISLFGRDCSVQRRHQKIIEEAPV
TIAKAETFHEMEKAAVRLGKLVGYVSAGTVEYLYSHDDGKFYFLELNPRLQVEHPTTE
MVSGVNLPAAQLQIAMGIPMHRISDIRTLYGMNPHSASEIDFEFKTQDATKKQRRPIP
KGHCTACRITSEDPNDGFKPSGGTLHELNFRSSSNVWGYFSVGNNGNIHSFSDSQFGH
IFAFGENRQASRKHMVVALKELSIRGDFRTTVEYLIKLLETEDFEDNTITTGWLDDLI
THKMTAEKPDPTLAVICGAATKAFLASEEARHKYIESLQKGQVLSKDLLQTMFPVDFI
HEGKRYKFTVAKSGNDRYTLFINGSKCDIILRQLSDGGLLIAIGGKSHTIYWKEEVAA
TRLSVDSMTTLLEVENDPTQLRTPSPGKLVKFLVENGEHIIKGQPYAEIEVMKMQMPL
VSQENGIVQLLKQPGSTIVAGDIMAIMTLDDPSKVKHALPFEGMLPDFGSPVIEGTKP
AYKFKSLVSTLENILKGYDNQVIMNASLQQLIEVLRNPKLPYSEWKLHISALHSRLPA
KLDEQMEELVARSLRRGAVFPARQLSKLIDMAVKNPEYNPDKLLGAVVEPLADIAHKY
SNGLEAHEHSIFVHFLEEYYEVEKLFNGPNVREENIILKLRDENPKDLDKVALTVLSH
SKVSAKNNLILAILKHYQPLCKLSSKVSAIFSTPLQHIVELESKATAKVALQAREILI
QGALPSVKERTEQIEHILKSSVVKVAYGSSNPKRSEPDLNILKDLIDSNYVVFDVLLQ
FLTHQDPVVTAAAAQVYIRRAYRAYTIGDIRVHEGVTVPIVEWKFQLPSAAFSTFPTV
KSKMGMNRAVSVSDLSYVANSQSSPLREGILMAVDHLDDVDEILSQSLEVIPRHQSSS
NGPAPDRSGSSASLSNVANVCVASTEGFESEEEILVRLREILDLNKQELINASIRRIT
FMFGFKDGSYPKYYTFNGPNYNENETIRHIEPALAFQLELGRLSNFNIKPIFTDNRNI
HVYEAVSKTSPLDKRFFTRGIIRTGHIRDDISIQEYLTSEANRLMSDILDNLEVTDTS
NSDLNHIFINFIAVFDISPEDVEAAFGGFLERFGKRLLRLRVSSAEIRIIIKDPQTGA
PVPLRALINNVSGYVIKTEMYTEVKNAKGEWVFKSLGKPGSMHLRPIATPYPVKEWLQ
PKRYKAHLMGTTYVYDFPELFRQASSSQWKNFSADVKLTDDFFISNELIEDENGELTE
VEREPGANAIGMVAFKITVKTPEYPRGRQFVVVANDITFKIGSFGPQEDEFFNKVTEY
ARKRGIPRIYLAANSGARIGMAEEIVPLFQVAWNDAANPDKGFQYLYLTSEGMETLKK
FDKENSVLTERTVINGEERFVIKTIIGSEDGLGVECLRGSGLIAGATSRAYHDIFTIT
LVTCRSVGIGAYLVRLGQRAIQVEGQPIILTGAPAINKMLGREVYTSNLQLGGTQIMY
NNGVSHLTAVDDLAGVEKIVEWMSYVPAKRNMPVPILETKDTWDRPVDFTPTNDETYD
VRWMIEGRETESGFEYGLFDKGSFFETLSGWAKGVVVGRARLGGIPLGVIGVETRTVE
NLIPADPANPNSAETLIQEPGQVWHPNSAFKTAQAINDFNNGEQLPMMILANWRGFSG
GQRDMFNEVLKYGSFIVDALVDYKQPIIIYIPPTGELRGGSWVVVDPTINADQMEMYA
DVNARAGVLEPQGMVGIKFRREKLLDTMNRLDDKYRELRSQLSNKSLAPEVHQQISKQ
LADRERELLPIYGQISLQFADLHDRSSRMVAKGVISKELEWTEARRFFFWRLRRRLNE
EYLIKRLSHQVGEASRLEKIARIRSWYPASVDHEDDRQVATWIEENYKTLDDKLKGLK
LESFAQDLAKKIRSDHDNAIDGLSEVIKMLSTDDKEKLLKTLK"
gene 662913..663581
/gene="TIM23"
/locus_tag="YNR017W"
/gene_synonym="MAS6; MIM23; MPI3"
/db_xref="GeneID:855751"
mRNA 662913..663581
/gene="TIM23"
/locus_tag="YNR017W"
/gene_synonym="MAS6; MIM23; MPI3"
/product="Tim23p"
/transcript_id="NM_001183194.3"
/db_xref="GI:398365640"
/db_xref="GeneID:855751"
CDS 662913..663581
/gene="TIM23"
/locus_tag="YNR017W"
/gene_synonym="MAS6; MIM23; MPI3"
/note="Essential component of the Translocase of the Inner
Mitochondrial membrane (TIM23 complex); involved in
protein import into mitochondrial matrix and inner
membrane; with Tim17p, contributes to architecture and
function of the import channel"
/codon_start=1
/product="Tim23p"
/protein_id="NP_014414.3"
/db_xref="GI:398365641"
/db_xref="SGD:S000005300"
/db_xref="GeneID:855751"
/translation="MSWLFGDKTPTDDANAAVGGQDTTKPKELSLKQSLGFEPNINNI
ISGPGGMHVDTARLHPLAGLDKGVEYLDLEEEQLSSLEGSQGLIPSRGWTDDLCYGTG
AVYLLGLGIGGFSGMMQGLQNIPPNSPGKLQLNTVLNHITKRGPFLGNNAGILALSYN
IINSTIDALRGKHDTAGSIGAGALTGALFKSSKGLKPMGYSSAMVAAACAVWCSVKKR
LLEK"
gene 664270..664944
/gene="RCF2"
/locus_tag="YNR018W"
/gene_synonym="AIM38"
/db_xref="GeneID:855752"
mRNA 664270..664944
/gene="RCF2"
/locus_tag="YNR018W"
/gene_synonym="AIM38"
/product="Rcf2p"
/transcript_id="NM_001183195.1"
/db_xref="GI:296147780"
/db_xref="GeneID:855752"
CDS 664270..664944
/gene="RCF2"
/locus_tag="YNR018W"
/gene_synonym="AIM38"
/note="Cytochrome c oxidase subunit; has a role in
assembly of respiratory supercomplexes; similar to Rcf1p,
and either Rcf1p or Rcf2p is required for late-stage
assembly of the Cox12p and Cox13p subunits and for
cytochrome c oxidase activity; associates with the
cytochrome c oxidase - cytochrome bc1 supercomplex; null
mutant accumulates reactive oxygen species; member of the
conserved hypoxia induced gene family; C. elegans homolog
is functional in yeast"
/codon_start=1
/product="Rcf2p"
/protein_id="NP_014415.1"
/db_xref="GI:6324345"
/db_xref="SGD:S000005301"
/db_xref="GeneID:855752"
/translation="MKILTQDEIEAHRSHTLKGGIEGALAGFAISAIIFKVLPRRYPK
FKPSTLTWSIKTALWITPPTVLTAICAEEASNNFDATMYGSGSSSEDALDEHRRWKSL
STKDKFVEGLSNNKYKIITGAWAASLYGSWVIVNKDPIMTKAQKIVQARMYAQFITVG
LLLASVGLSMYENKLHPNKQKVNEMRRWENALRVAEEEERLEKEGRRTGYVSNEERIN
SKIFKS"
gene 665339..667267
/gene="ARE2"
/locus_tag="YNR019W"
/gene_synonym="SAT1"
/db_xref="GeneID:855753"
mRNA 665339..667267
/gene="ARE2"
/locus_tag="YNR019W"
/gene_synonym="SAT1"
/product="Are2p"
/transcript_id="NM_001183196.1"
/db_xref="GI:296147781"
/db_xref="GeneID:855753"
CDS 665339..667267
/gene="ARE2"
/locus_tag="YNR019W"
/gene_synonym="SAT1"
/EC_number="2.3.1.26"
/note="Acyl-CoA:sterol acyltransferase; endoplasmic
reticulum enzyme that contributes the major sterol
esterification activity in the presence of oxygen; ARE2
has a paralog, ARE1, that arose from the whole genome
duplication"
/codon_start=1
/product="Are2p"
/protein_id="NP_014416.1"
/db_xref="GI:6324346"
/db_xref="SGD:S000005302"
/db_xref="GeneID:855753"
/translation="MDKKKDLLENEQFLRIQKLNAADAGKRQSITVDDEGELYGLDTS
GNSPANEHTATTITQNHSVVASNGDVAFIPGTATEGNTEIVTEEVIETDDNMFKTHVK
TLSSKEKARYRQGSSNFISYFDDMSFEHRPSILDGSVNEPFKTKFVGPTLEKEIRRRE
KELMAMRKNLHHRKSSPDAVDSVGKNDGAAPTTVPTAATSETVVTVETTIISSNFSGL
YVAFWMAIAFGAVKALIDYYYQHNGSFKDSEILKFMTTNLFTVASVDLLMYLSTYFVV
GIQYLCKWGVLKWGTTGWIFTSIYEFLFVIFYMYLTENILKLHWLSKIFLFLHSLVLL
MKMHSFAFYNGYLWGIKEELQFSKSALAKYKDSINDPKVIGALEKSCEFCSFELSSQS
LSDQTQKFPNNISAKSFFWFTMFPTLIYQIEYPRTKEIRWSYVLEKICAIFGTIFLMM
IDAQILMYPVAMRALAVRNSEWTGILDRLLKWVGLLVDIVPGFIVMYILDFYLIWDAI
LNCVAELTRFGDRYFYGDWWNCVSWADFSRIWNIPVHKFLLRHVYHSSMSSFKLNKSQ
ATLMTFFLSSVVHELAMYVIFKKLRFYLFFFQMLQMPLVALTNTKFMRNRTIIGNVIF
WLGICMGPSVMCTLYLTF"
gene complement(667410..668222)
/gene="ATP23"
/locus_tag="YNR020C"
/db_xref="GeneID:855754"
mRNA complement(667410..668222)
/gene="ATP23"
/locus_tag="YNR020C"
/product="Atp23p"
/transcript_id="NM_001183197.3"
/db_xref="GI:398365654"
/db_xref="GeneID:855754"
CDS complement(667410..668222)
/gene="ATP23"
/locus_tag="YNR020C"
/note="Putative metalloprotease of the mitochondrial inner
membrane, required for processing of Atp6p; has an
additional role in assembly of the F0 sector of the F1F0
ATP synthase complex"
/codon_start=1
/product="Atp23p"
/protein_id="NP_014417.3"
/db_xref="GI:398365655"
/db_xref="SGD:S000005303"
/db_xref="GeneID:855754"
/translation="MTMRTNKKNKSSNIKMIRRVRHNLYNQNQGKLIVPNFFFFWHDM
NSSGDNAGFEWWRRTMQYKTGIGLTPEEKTRYEDDSKARELKKECLKCYEYRDWMLKY
SPTVRFMVQAITKLNKGSDSKFDDSKIICDYCPDWKGGGFHPELGILLCQNRLRDKWH
LEDTLSHELIHYFDDLKWQIDWLNLKHHACSEIRASSLSGECRFWEEFKRRGFRTGFH
VARGHQDCVRRRAIISVSGNPNCQSKEHAAKIVDEVWDSCFADTRPFDEIYR"
gene 668377..669591
/locus_tag="YNR021W"
/db_xref="GeneID:855755"
mRNA 668377..669591
/locus_tag="YNR021W"
/product="hypothetical protein"
/transcript_id="NM_001183198.3"
/db_xref="GI:398365664"
/db_xref="GeneID:855755"
CDS 668377..669591
/locus_tag="YNR021W"
/note="hypothetical protein; green fluorescent protein
(GFP)-fusion protein localizes to the endoplasmic
reticulum; YNR021W is not an essential gene"
/codon_start=1
/product="hypothetical protein"
/protein_id="NP_014418.3"
/db_xref="GI:398365665"
/db_xref="SGD:S000005304"
/db_xref="GeneID:855755"
/translation="MSSSIFGPLTGFLERVNSLNAPYQALSYDEQKAMTIWQRVKFYN
WTFELCALGVLFLVYAFYKFGNSVNLKRGNQIFQSLHSFLANDLKFSRVGFNINDSKI
FTVEHQNTWFSSFATGRSAIKSINLNLHLVARSNPFSMCLEYLLGFFFASLKSKQLEE
FMEIVIRPNGILVTSESAHPNKNAHEILTKFRFVTSIVNKEFMNQARTENYFLSIAHT
SENDKLPNNFVYMSDVNQLSGFMFHYSKPYEVLSQAGNLLKYISFTDLPVNPPRDDKE
WESSIEPKAIIRCAVPQNENELKLLNQIISLVVEIYDGFTQDLVQQSPNLFITNDILK
RTTNLRQQELNKIKKFMKETELELAKEKKLELEKAKRRQLKASGQQEKVDQKMKEKRE
RRLKNKQRTRFQ"
gene complement(669774..670193)
/gene="MRPL50"
/locus_tag="YNR022C"
/db_xref="GeneID:855756"
mRNA complement(669774..670193)
/gene="MRPL50"
/locus_tag="YNR022C"
/product="mitochondrial 54S ribosomal protein MRPL50"
/transcript_id="NM_001183199.1"
/db_xref="GI:296147784"
/db_xref="GeneID:855756"
CDS complement(669774..670193)
/gene="MRPL50"
/locus_tag="YNR022C"
/note="Mitochondrial ribosomal protein of the large
subunit, not essential for mitochondrial translation"
/codon_start=1
/product="mitochondrial 54S ribosomal protein MRPL50"
/protein_id="NP_014419.1"
/db_xref="GI:6324349"
/db_xref="SGD:S000005305"
/db_xref="GeneID:855756"
/translation="MLHCTQVCLSALTKRTHRVKVQVLKDFPRFQLYKGQVANVKPSL
MRNYLHNFNGAKYILSEEHDINTELLKQYQTLEAKLEEDHQQLSKRHETEVQKNMELR
KESVFGHKKEEKPKEEKKGLLDSGITIEEVKIPGLDI"
gene 670418..672118
/gene="SNF12"
/locus_tag="YNR023W"
/gene_synonym="SWP73"
/db_xref="GeneID:855757"
mRNA 670418..672118
/gene="SNF12"
/locus_tag="YNR023W"
/gene_synonym="SWP73"
/product="Snf12p"
/transcript_id="NM_001183200.1"
/db_xref="GI:296147785"
/db_xref="GeneID:855757"
CDS 670418..672118
/gene="SNF12"
/locus_tag="YNR023W"
/gene_synonym="SWP73"
/note="73 kDa subunit of the SWI/SNF chromatin remodeling
complex involved in transcriptional regulation; homolog of
Rsc6p subunit of the RSC chromatin remodeling complex;
relocates to the cytosol under hypoxic conditions;
deletion mutants are temperature-sensitive"
/codon_start=1
/product="Snf12p"
/protein_id="NP_014420.1"
/db_xref="GI:6324350"
/db_xref="SGD:S000005306"
/db_xref="GeneID:855757"
/translation="MSKVMKPSNGKGSRKSSKAATPDTKNFFHAKKKDPVNQDKANNA
SQITPTVPHSHPSDMVIPDHLAELIPELYSFQQLVDSEKRLDHFIHLRNLHMKRMVAQ
WERSKLSQEFLYPHLNFPNVKFLRIFISNVSENQPWQMDTNNEADLMALENATWTMRI
EGRLLDNVQANDPAREKFSSFIESIVVDFKNKENDNVPSTKFNAAPEENATEGPSDKK
LNLNLPLQFSLPNGDNSTTTNTDQNNATMGEETAKKDMSSTTPKLESVKWQYDPNNPV
DFDGLDIKRVGSENVECTISILRKSSPEEPFMSYSPQLTAIIGLKSGTSHDAIFSIYK
YIHLNELLTNDESAFENLMGNRNNHNSNTSTSKMLDAASSQVSIVKLDTQLITLLPSS
LKESSPDTMKLTDLLSLINSTHLLPLQPIEIDYTVRVDKASTYGELVLDIEVPDVNAL
KFNNTQRESQIGAAELNENARELEQIKPKIALQDKEITSVLSNLHESNKRYRFFKKIS
EDPVKALNECIASTSNALKVLSGDEGYNEDMVRRANFYKENEAMLRENIEVILSNGRM
"
gene 672409..672969
/gene="MPP6"
/locus_tag="YNR024W"
/db_xref="GeneID:855758"
mRNA 672409..672969
/gene="MPP6"
/locus_tag="YNR024W"
/product="Mpp6p"
/transcript_id="NM_001183201.3"
/db_xref="GI:398365678"
/db_xref="GeneID:855758"
CDS 672409..672969
/gene="MPP6"
/locus_tag="YNR024W"
/note="Nuclear exosome-associated RNA binding protein;
involved in surveillance of pre-rRNAs and pre-mRNAs, and
the degradation of cryptic non-coding RNAs (ncRNA);
copurifies with ribosomes"
/codon_start=1
/product="Mpp6p"
/protein_id="NP_014421.3"
/db_xref="GI:398365679"
/db_xref="SGD:S000005307"
/db_xref="GeneID:855758"
/translation="MSANNGVTGKLSSRVMNMKFMKFGKTDDEESSNSNTPSNINSDV
EPIEQKGKLFGLDDSAWDLNSYKDDLKKISGKEKKKVKRVVYKKRPNLIISNVGYSEL
RKPEGVISGRKTFGDNSDDSGSRKRKFDEGEQNEDEKRDAKDKEFTGSQDDGEDEYDL
DKLFKDSIKKKKTNHNGKNKNRNSKK"
gene complement(673274..674689)
/gene="SEC12"
/locus_tag="YNR026C"
/gene_synonym="SED2"
/db_xref="GeneID:855760"
mRNA complement(673274..674689)
/gene="SEC12"
/locus_tag="YNR026C"
/gene_synonym="SED2"
/product="Sec12p"
/transcript_id="NM_001183203.1"
/db_xref="GI:296147787"
/db_xref="GeneID:855760"
CDS complement(673274..674689)
/gene="SEC12"
/locus_tag="YNR026C"
/gene_synonym="SED2"
/note="Guanine nucleotide exchange factor (GEF), activates
Sar1p by catalyzing the exchange of GDP for GTP; required
for the initiation of COPII vesicle formation in ER to
Golgi transport; glycosylated integral membrane protein of
the ER"
/codon_start=1
/product="Sec12p"
/protein_id="NP_014423.1"
/db_xref="GI:6324353"
/db_xref="SGD:S000005309"
/db_xref="GeneID:855760"
/translation="MKFVTASYNVGYPAYGAKFLNNDTLLVAGGGGEGNNGIPNKLTV
LRVDPTKDTEKEQFHILSEFALEDNDDSPTAIDASKGIILVGCNENSTKITQGKGNKH
LRKFKYDKVNDQLEFLTSVDFDASTNADDYTKLVYISREGTVAAIASSKVPAIMRIID
PSDLTEKFEIETRGEVKDLHFSTDGKVVAYITGSSLEVISTVTGSCIARKTDFDKNWS
LSKINFIADDTVLIAASLKKGKGIVLTKISIKSGNTSVLRSKQVTNRFKGITSMDVDM
KGELAVLASNDNSIALVKLKDLSMSKIFKQAHSFAITEVTISPDSTYVASVSAANTIH
IIKLPLNYANYTSMKQKISKFFTNFILIVLLSYILQFSYKHNLHSMLFNYAKDNFLTK
RDTISSPYVVDEDLHQTTLFGNHGTKTSVPSVDSIKVHGVHETSSVNGTEVLCTESNI
INTGGAEFEITNATFREIDDA"
gene 674923..675876
/gene="BUD17"
/locus_tag="YNR027W"
/db_xref="GeneID:855761"
mRNA 674923..675876
/gene="BUD17"
/locus_tag="YNR027W"
/product="putative pyridoxal kinase BUD17"
/transcript_id="NM_001183204.1"
/db_xref="GI:296147788"
/db_xref="GeneID:855761"
CDS 674923..675876
/gene="BUD17"
/locus_tag="YNR027W"
/note="Putative pyridoxal kinase, a key enzyme in vitamin
B6 metabolism; involved in bud-site selection; diploid
mutants display a random rather than a bipolar budding
pattern; similarity to yeast BUD16 and human pyridoxal
kinase (PDXK)"
/codon_start=1
/product="putative pyridoxal kinase BUD17"
/protein_id="NP_014424.1"
/db_xref="GI:6324354"
/db_xref="SGD:S000005310"
/db_xref="GeneID:855761"
/translation="MTSTLHTTKKVLSIQSHVIHGYVGNKAATFPLQYRGWDVDVLNT
VQFSNHSGYAHFTGFKCSTEELVDIVEKGLIGSLRIKYDAVLSGYLPNVQALQKVAGI
VGQLCEGSENVKWILDPVLGDNGRLYVDRECVAVYQDILQNFKIFLATPNQFEMELLV
GMSIRTLDDAKQAFKLFHKKYPRVSRIVVTSLELSEFLSNDTYVVAGFDCSASEEIFF
YEIPKINAKFSGSGDLISAMLTDSLLGDRRCTQLSLSASLGQVLWLVTSILQKTYDLN
IAERGPQDSTIDIKDLKLIQCRDILKQDLIPSIGKPKTIKI"
gene 676177..677103
/gene="CPR8"
/locus_tag="YNR028W"
/db_xref="GeneID:855762"
mRNA 676177..677103
/gene="CPR8"
/locus_tag="YNR028W"
/product="peptidylprolyl isomerase family protein CPR8"
/transcript_id="NM_001183205.3"
/db_xref="GI:398365694"
/db_xref="GeneID:855762"
CDS 676177..677103
/gene="CPR8"
/locus_tag="YNR028W"
/EC_number="5.2.1.8"
/note="Peptidyl-prolyl cis-trans isomerase (cyclophilin),
catalyzes the cis-trans isomerization of peptide bonds
N-terminal to proline residues; similarity to Cpr4p
suggests a potential role in the secretory pathway"
/codon_start=1
/product="peptidylprolyl isomerase family protein CPR8"
/protein_id="NP_014425.3"
/db_xref="GI:398365695"
/db_xref="SGD:S000005311"
/db_xref="GeneID:855762"
/translation="MKSFFLYLYVAFMFSCITALPLPVDNKRASSDSLDLKKKYAPDP
PITHNVNIGIVFTDPESSEEAGRLITIDLYGTMVPKTVMTFCQYVDSVKDRLASRHSY
SPERDFDKILPNGAIEGSSVSSSSIEETEMLAPKLPEENHSLIHDRPGRVSMIKDDKG
LKFIIETSETPLEGESVVFGQVTAGLKDLMDKLANVKTDENGKPEQPITIGYISSQEH
RIQHAKEAHEKYLQRLQDYQNGDLEKGITLKNYLYQGSQRKLEDAKYNQLHHPLPKIM
LGISVLLLFYVLAKYRKRIFNRSSKIVSIRED"
gene complement(677199..678488)
/locus_tag="YNR029C"
/db_xref="GeneID:855763"
mRNA complement(677199..678488)
/locus_tag="YNR029C"
/product="hypothetical protein"
/transcript_id="NM_001183206.3"
/db_xref="GI:398365700"
/db_xref="GeneID:855763"
CDS complement(677199..678488)
/locus_tag="YNR029C"
/note="hypothetical protein, deletion confers reduced
fitness in saline"
/codon_start=1
/product="hypothetical protein"
/protein_id="NP_014426.3"
/db_xref="GI:398365701"
/db_xref="SGD:S000005312"
/db_xref="GeneID:855763"
/translation="MSALRNIKFNEEEDGELPCLVTGEENNLQEILENVSYDGGNIVS
DAKVERVNKQVENTSAGATDVHEKKRIPVSIITGYLGSGKSTLLEKIALKGADKKIAV
ILNEFGDSSEIEKAMTIKNGSNSYQEWLDLGNGCLCCSLKNIGVKAIEDMVERSPGKI
DYILLETSGIADPAPIAKMFWQDEGLNSSVYIDGIITVLDCEHILKCLDDISIDAHWH
GDKVGLEGNLTIAHFQLAMADRIIMNKYDTIEHSPEMVKQLKERVREINSIAPMFFTK
YSDTPIQNLLDIHAYDSVRISDILDSGSGNGTIHDDRMGTIMLTFRPLKNEEEYNNKF
IKQFLQPLLWKNFGAMTVLGGRRRDDGRDWEVQRTKGLILIEGENPIARVIQGVRDTY
DVFPGKYDGSNKECKIVLIGKYLEKESIEELLRKTLE"
gene 678799..680454
/gene="ALG12"
/locus_tag="YNR030W"
/gene_synonym="ECM39"
/db_xref="GeneID:855764"
mRNA 678799..680454
/gene="ALG12"
/locus_tag="YNR030W"
/gene_synonym="ECM39"
/product="dolichyl-P-Man:Man(7)GlcNAc(2)-PP-dolichol
alpha-1,6-mannosyltransferase"
/transcript_id="NM_001183207.1"
/db_xref="GI:296147791"
/db_xref="GeneID:855764"
CDS 678799..680454
/gene="ALG12"
/locus_tag="YNR030W"
/gene_synonym="ECM39"
/note="Alpha-1,6-mannosyltransferase localized to the ER;
responsible for the addition of the alpha-1,6 mannose to
dolichol-linked Man7GlcNAc2, acts in the dolichol pathway
for N-glycosylation"
/codon_start=1
/product="dolichyl-P-Man:Man(7)GlcNAc(2)-PP-dolichol
alpha-1,6-mannosyltransferase"
/protein_id="NP_014427.1"
/db_xref="GI:6324357"
/db_xref="SGD:S000005313"
/db_xref="GeneID:855764"
/translation="MRWSVLDTVLLTVISFHLIQAPFTKVEESFNIQAIHDILTYSVF
DISQYDHLKFPGVVPRTFVGAVIIAMLSRPYLYLSSLIQTSRPTSIDVQLVVRGIVGL
TNGLSFIYLKNCLQDMFDEITEKKKEENEDKDIYIYDSAGTWFLLFLIGSFHLMFYST
RTLPNFVMTLPLTNVALGWVLLGRYNAAIFLSALVAIVFRLEVSALSAGIALFSVIFK
KISLFDAIKFGIFGLGLGSAISITVDSYFWQEWCLPEVDGFLFNVVAGYASKWGVEPV
TAYFTHYLRMMFMPPTVLLLNYFGYKLAPAKLKIVSLASLFHIIVLSFQPHKEWRFII
YAVPSIMLLGATGAAHLWENMKVKKITNVLCLAILPLSIMTSFFISMAFLYISRMNYP
GGEALTSFNDMIVEKNITNATVHISIPPCMTGVTLFGELNYGVYGINYDKTENTTLLQ
EMWPSFDFLITHEPTASQLPFENKTTNHWELVNTTKMFTGFDPTYIKNFVFQERVNVL
SLLKQIIFDKTPTVFLKELTANSIVKSDVFFTYKRIKQDEKTD"
gene complement(680694..685433)
/gene="SSK2"
/locus_tag="YNR031C"
/db_xref="GeneID:855765"
mRNA complement(680694..685433)
/gene="SSK2"
/locus_tag="YNR031C"
/product="Ssk2p"
/transcript_id="NM_001183208.1"
/db_xref="GI:296147792"
/db_xref="GeneID:855765"
CDS complement(680694..685433)
/gene="SSK2"
/locus_tag="YNR031C"
/EC_number="2.7.11.25"
/note="MAP kinase kinase kinase of the HOG1
mitogen-activated signaling pathway; interacts with Ssk1p,
leading to autophosphorylation and activation of Ssk2p
which phosphorylates Pbs2p; also mediates actin
cytoskeleton recovery from osmotic stress"
/codon_start=1
/product="Ssk2p"
/protein_id="NP_014428.1"
/db_xref="GI:6324358"
/db_xref="SGD:S000005314"
/db_xref="GeneID:855765"
/translation="MSHSDYFNYKPYGDSTEKPSSSKMRQSSSSSSSRLRSESLGRNS
NTTQARVASSPISPGLHSTQYFRSPNAVYSPGESPLNTVQLFNRLPGIPQGQFFHQNA
ISGSSSSSARSSRRPSNIGLPLPKNPQQSLPKLSTQPVPVHKKVEASKTESEIIKKPA
PVNSNQDPLLTTPTLVISPELASLNTTNTSIMSTPQNITNQTSNKHIPTRSQPNGSTS
SSTLQDIVTTNSSQRSVGHHGGSTTSLRTYKKQYVLNEQLYLRKMRNRANDDYYTRGI
VASSNFEDDEENFSNKGEDDLELEMDDLLKVEGEDKDNDFNFGYNFITSSTKNNENVV
SMSLNYLKGKLDWLRDVNNDQPCEIEDEEWHSILGSEDLLSKLLQNPMVNNRFEWQTM
LSKVLKGDIVRNEKTKIANQGKGPGFNTQFSDDIWIELKAWMNGRTVEDQNKSLRIFR
DSTDSVFQEIMAFKLEDNMSADEAAETIKSLVDKYYRVLNLWPNIKRMHAEKPITKTE
AFRNRIDTLNSWLNFKFNFDTNIAYLKKWIVGNKELESTTEVDNTTVNLDDPAVFATN
CKRFAEQIMKEKDIELIFQKKIFFPLAPWILKAKFFFLKYQKTWNELNLSYLDQDLEF
LLMFPMRLVKDIILIRLSYAKKIQNPTLMMIDQMMDDFSTYIKLAVQMKFTVASYCND
WFFKVKIDPEFDHTVVEGLEYFFSILELRILYSGKNSFKTSKEPDLLLKYWEMFRNVG
YYIDDAGELIAAEFTKLTLRLVHRLHAYLLRQQNTPPKLENEAAAEKWLVQIFEILGS
MKRKLNRFTNILTKAFQNFVRYKIEDHNYLLKQLKETGHFLIYTGGYLEQNGTYLIGS
PELLGCKDDDILRIIKNSDIGCDLVPKLEINNSLTIYNALDDNWNSNSSLGSDISNDG
TPFYYIKNDLTTQPRSYNGNRVNREPDFENSRSTEEEFYELETRLNSLGYVLVLTPQE
PLLWEGEMYNLSDNKTIKPEGLNLKVIPNSIDLMCQGSSYALEYQCDRFQQISGSSVS
FLEKKSSSETVKNNLQRINKAYFRCTYSVLKNYTKIVTTFKKVSPVNDLLNNIFLFGR
DFGLNFLRINVANNEKRSIIILLMMRLSIGWLKFLAEDCDPTDQRVFRWCVTSMEFAM
HMVSGWNILALDECQFSSLKQKISECMSLLISHFDIIGARSIEVEKINQQARSNLDLE
DVFDDDMMLQVNSEFRVQSIMELEERIKRNPHQTGKVIDDSDKGNKYLVSLASSISNV
SMRWQKRNFIGGGTFGRVYSAVDLDNGEILAVKEINIQDSKSMQKIFPLIKEEMSVLE
ILNHPNIVSYYGVEVHRDKVNIFMEYCEGGSLAALLEHGRIEDEMVTQVYTLQLLEGL
AYLHESGIVHRDVKPENILLDFNGVIKYVDFGAAKKIANNGTRLASMNKIENADGEHE
DVTHVSDSKAVKNNENALLDMMGTPMYMAPESITGSTTKGKLGADDVWSLGCVVLEMI
TGRRPWANLDNEWAIMYHVAAGHTPQFPTKDEVSSAGMKFLERCLIQNPSKRASAVEL
LMDPWIVQIREIAFGDDSSSTDTEERE"
gene 686010..687116
/gene="PPG1"
/locus_tag="YNR032W"
/db_xref="GeneID:855766"
mRNA 686010..687116
/gene="PPG1"
/locus_tag="YNR032W"
/product="Ppg1p"
/transcript_id="NM_001183209.3"
/db_xref="GI:398365710"
/db_xref="GeneID:855766"
CDS 686010..687116
/gene="PPG1"
/locus_tag="YNR032W"
/EC_number="3.1.3.16"
/note="Putative serine/threonine protein phosphatase of
the type 2A-like phosphatase family, required for glycogen
accumulation; interacts with Tap42p, which binds to and
regulates other protein phosphatases"
/codon_start=1
/product="Ppg1p"
/protein_id="NP_014429.3"
/db_xref="GI:398365711"
/db_xref="SGD:S000005315"
/db_xref="GeneID:855766"
/translation="MELDECLERLYKAQLLPEVTVRALCFKLKEMLVKESNVIHIQTP
VTVVGDMHGQFHDMLEIFQIGGPVPDTNYLFLGDYVDRGLYSVETIMLLIVLKLRYPS
RIHLLRGNHESRQITQSYGFYTECLNKYGGNSRVWQYLTDIFDYLVLCCIIDDEIFCV
HGGLSPNVQTIDQIKIIDRFREIPHDGAMADLVWSDPEENNNPTLDHPDNSGQHFQVS
PRGAGYTFGRSVVEKFLRMNDMNRIYRAHQLCNEGYQIYFDGLVTTVWSAPNYCYRCG
NKASILELYSKDQFYFNVFEEAPENKLLKENSMNDNALEDSISNPVANRKLIADYFED
DSASADGSTDPEMYIFSDVYQARSASNRHVDYFL"
gene complement(687243..687464)
/gene="HUB1"
/locus_tag="YNR032C-A"
/db_xref="GeneID:855767"
mRNA complement(687243..687464)
/gene="HUB1"
/locus_tag="YNR032C-A"
/product="Hub1p"
/transcript_id="NM_001184344.1"
/db_xref="GI:296147794"
/db_xref="GeneID:855767"
CDS complement(687243..687464)
/gene="HUB1"
/locus_tag="YNR032C-A"
/note="Ubiquitin-like protein modifier; promotes
alternative splicing of SRC1 pre-mRNA; binds
non-covalently to the HIND domain of Snu66, may function
in modification of Sph1p and Hbt1p, functionally
complemented by the human or S. pombe ortholog; mechanism
of Hub1p adduct formation not yet clear"
/codon_start=1
/product="Hub1p"
/protein_id="NP_014430.1"
/db_xref="GI:6324360"
/db_xref="SGD:S000007251"
/db_xref="GeneID:855767"
/translation="MIEVVVNDRLGKKVRVKCLAEDSVGDFKKVLSLQIGTQPNKIVL
QKGGSVLKDHISLEDYEVHDQTNLELYYL"
gene 687635..689998
/gene="ABZ1"
/locus_tag="YNR033W"
/db_xref="GeneID:855768"
mRNA 687635..689998
/gene="ABZ1"
/locus_tag="YNR033W"
/product="4-amino-4-deoxychorismate synthase"
/transcript_id="NM_001183210.1"
/db_xref="GI:296147795"
/db_xref="GeneID:855768"
CDS 687635..689998
/gene="ABZ1"
/locus_tag="YNR033W"
/EC_number="2.6.1.85"
/note="Para-aminobenzoate (PABA) synthase; has similarity
to Escherichia coli PABA synthase components PabA and
PabB; required for the synthesis of para-aminobenzoic
acid, an important intermediate for folate and ubiquinone
Q biosynthesis; protein abundance increases in response to
DNA replication stress"
/codon_start=1
/product="4-amino-4-deoxychorismate synthase"
/protein_id="NP_014431.1"
/db_xref="GI:6324361"
/db_xref="SGD:S000005316"
/db_xref="GeneID:855768"
/translation="MLSDTIDTKQQQQQLHVLFIDSYDSFTYNVVRLIEQQTDISPGV
NAVHVTTVHSDTFQSMDQLLPLLPLFDAIVVGPGPGNPNNGAQDMGIISELFENANGK
LDEVPILGICLGFQAMCLAQGADVSELNTIKHGQVYEMHLNDAARACGLFSGYPDTFK
STRYHSLHVNAEGIDTLLPLCTTEDENGILLMSAQTKNKPWFGVQYHPESCCSELGGL
LVSNFLKLSFINNVKTGRWEKKKLNGEFSDILSRLDRTIDRDPIYKVKEKYPKGEDTT
YVKQFEVSEDPKLTFEICNIIREEKFVMSSSVISENTGEWSIIALPNSASQVFTHYGA
MKKTTVHYWQDSEISYTLLKKCLDGQDSDLPGSLEVIHEDKSQFWITLGKFMENKIID
NHREIPFIGGLVGILGYEIGQYIACGRCNDDENSLVPDAKLVFINNSIVINHKQGKLY
CISLDNTFPVALEQSLRDSFVRKKNIKQSLSWPKYLPEEIDFIITMPDKLDYAKAFKK
CQDYMHKGDSYEMCLTTQTKVVPSAVIEPWRIFQTLVQRNPAPFSSFFEFKDIIPRQD
ETPPVLCFLSTSPERFLKWDADTCELRPIKGTVKKGPQMNLAKATRILKTPKEFGENL
MILDLIRNDLYELVPDVRVEEFMSVQEYATVYQLVSVVKAHGLTSASKKTRYSGIDVL
KHSLPPGSMTGAPKKITVQLLQDKIESKLNKHVNGGARGVYSGVTGYWSVNSNGDWSV
NIRCMYSYNGGTSWQLGAGGAITVLSTLDGELEEMYNKLESNLQIFM"
gene 690321..691286
/gene="SOL1"
/locus_tag="YNR034W"
/db_xref="GeneID:855769"
mRNA 690321..691286
/gene="SOL1"
/locus_tag="YNR034W"
/product="Sol1p"
/transcript_id="NM_001183211.3"
/db_xref="GI:398365724"
/db_xref="GeneID:855769"
CDS 690321..691286
/gene="SOL1"
/locus_tag="YNR034W"
/EC_number="3.1.1.31"
/note="Protein with a possible role in tRNA export; shows
similarity to 6-phosphogluconolactonase non-catalytic
domains but does not exhibit this enzymatic activity;
homologous to Sol3p and Sol4p; SOL1 has a paralog, SOL2,
that arose from the whole genome duplication; protein
abundance increases in response to DNA replication stress"
/codon_start=1
/product="Sol1p"
/protein_id="NP_014432.3"
/db_xref="GI:398365725"
/db_xref="SGD:S000005317"
/db_xref="GeneID:855769"
/translation="MTTTVPKVFAFHEFAGVAEAVADHVIHAQNSALKKGKVSRSTQM
SGTSLNGNGNTESKTMERVNSVRSNASSRGGSEDGATKKLKKEKERRFKIALSGGSLI
QVLHEGLLKRDDVQWGKWDIYFADERLVPFSSSESNYGLAKRKIFDLIDTEKYGTPKI
YHIDESLINDPQECADNYEKILIKGFAGRDSVKLPMFDLFLLGCAPDGHIASLFPNFQ
ENLRENLAWVIPVENAPSGPSNRISLTIPVICHSHRVTFVVEGATKAPVIKTIMERPE
KGLPSSIVNEGAAGRVSWFVDDDALKDVFVIKKKYKFYDDENLTE"
rep_origin 691486..691730
/note="ARS1427;
Autonomously Replicating Sequence"
/db_xref="SGD:S000118393"
gene 692561..692857
/locus_tag="YNR034W-A"
/db_xref="GeneID:855770"
mRNA 692561..692857
/locus_tag="YNR034W-A"
/product="hypothetical protein"
/transcript_id="NM_001184446.3"
/db_xref="GI:398365726"
/db_xref="GeneID:855770"
CDS 692561..692857
/locus_tag="YNR034W-A"
/note="hypothetical protein; expression is regulated by
Msn2p/Msn4p"
/codon_start=1
/product="hypothetical protein"
/protein_id="NP_061494.3"
/db_xref="GI:398365727"
/db_xref="SGD:S000007525"
/db_xref="GeneID:855770"
/translation="MKSSIPITEVLPRAVGSLTFDENYNLLDTSGVAKVIEKSPIAEI
IRKSNAELGRLGYSVYEDAQYIGHAFKKAGHFIVYFTPKNKNREGVVPPVGITN"
gene complement(693019..694047)
/gene="ARC35"
/locus_tag="YNR035C"
/gene_synonym="END9"
/db_xref="GeneID:855771"
mRNA complement(693019..694047)
/gene="ARC35"
/locus_tag="YNR035C"
/gene_synonym="END9"
/product="Arc35p"
/transcript_id="NM_001183212.1"
/db_xref="GI:296147798"
/db_xref="GeneID:855771"
CDS complement(693019..694047)
/gene="ARC35"
/locus_tag="YNR035C"
/gene_synonym="END9"
/note="Subunit of the ARP2/3 complex, which is required
for the motility and integrity of cortical actin patches;
required for cortical localization of calmodulin"
/codon_start=1
/product="Arc35p"
/protein_id="NP_014433.1"
/db_xref="GI:6324363"
/db_xref="SGD:S000005318"
/db_xref="GeneID:855771"
/translation="MLHLQPQNLLIQKTLNEAIEALRKGSPLTMDRIVSDFDYTTYHI
SNTAEDKSILLLSVKTKAWVSVSECQLDGSLTLLKFLADHYSSLGGVTIPSEVEPGYD
YTLQITLAELVQESILQLSVLKTIILSFPFELAISKFIELSQQQPAPVEAEITGGEVA
ANGDNTLFTIKYRDEENIFIKPSNDRVTIIFETIFQDETDKIFGKVFLQEFVDARKRN
RQIQSAPQVLYSHEPPLELKRLYQPPKVAEQSRRFITFVLFPRHFQTKELQFHSICQL
TLFRNYFHYHIKCSKAYMHSRMRFRVDSFIKVLNRAKVDEDDENDELSAEGRQQARRT
FTGRKIVY"
gene complement(694361..694822)
/gene="MRPS12"
/locus_tag="YNR036C"
/db_xref="GeneID:855772"
mRNA complement(694361..694822)
/gene="MRPS12"
/locus_tag="YNR036C"
/product="putative mitochondrial 37S ribosomal protein
MRPS12"
/transcript_id="NM_001183213.1"
/db_xref="GI:296147799"
/db_xref="GeneID:855772"
CDS complement(694361..694822)
/gene="MRPS12"
/locus_tag="YNR036C"
/note="Mitochondrial protein; may interact with ribosomes
based on co-purification experiments; similar to E. coli
and human mitochondrial S12 ribosomal proteins"
/codon_start=1
/product="putative mitochondrial 37S ribosomal protein
MRPS12"
/protein_id="NP_014434.1"
/db_xref="GI:6324364"
/db_xref="SGD:S000005319"
/db_xref="GeneID:855772"
/translation="MLSRFMSNTWCTPLRQAQRLFSSTTTMQATLNQIKRGSGPPRRK
KISTAPQLDQCPQRKGVVLRVMVLKPKKPNSAQRKACRVRLTNGNVVSAYIPGEGHDA
QEHSIVYVRGGRCQDLPGVKYHVIRGAGDLSGVVNRISSRSKYGAKKPSKS"
gene complement(695052..695327)
/gene="RSM19"
/locus_tag="YNR037C"
/db_xref="GeneID:855773"
mRNA complement(695052..695327)
/gene="RSM19"
/locus_tag="YNR037C"
/product="mitochondrial 37S ribosomal protein RSM19"
/transcript_id="NM_001183214.3"
/db_xref="GI:398365752"
/db_xref="GeneID:855773"
CDS complement(695052..695327)
/gene="RSM19"
/locus_tag="YNR037C"
/note="Mitochondrial ribosomal protein of the small
subunit, has similarity to E. coli S19 ribosomal protein"
/codon_start=1
/product="mitochondrial 37S ribosomal protein RSM19"
/protein_id="NP_014435.3"
/db_xref="GI:398365753"
/db_xref="SGD:S000005320"
/db_xref="GeneID:855773"
/translation="MQPAARLLSRSVWKGPNIVPLPIREAMTKGTPIRTNARAATILP
QFVGLKFQIHNGKEYVPIEISEDMVGHKLGEFAPTRKRFSYTQTKNK"
gene 695595..697484
/gene="DBP6"
/locus_tag="YNR038W"
/db_xref="GeneID:855774"
mRNA 695595..697484
/gene="DBP6"
/locus_tag="YNR038W"
/product="Dbp6p"
/transcript_id="NM_001183215.1"
/db_xref="GI:296147801"
/db_xref="GeneID:855774"
CDS 695595..697484
/gene="DBP6"
/locus_tag="YNR038W"
/EC_number="3.6.1.-"
/note="Essential protein involved in ribosome biogenesis;
putative ATP-dependent RNA helicase of the DEAD-box
protein family"
/codon_start=1
/product="Dbp6p"
/protein_id="NP_014436.1"
/db_xref="GI:6324366"
/db_xref="SGD:S000005321"
/db_xref="GeneID:855774"
/translation="MFASRFDPSQLTAPAASAPEGIVGTTPPAIVPLKRQATESDNEE
YGSHQDSDESSNSSSEEDEDRMQVDYGASEEDSSEVEEEESKPSTHSTVLSRFKQTVS
LQERLGASDIAESKEDEGIEDEAASTHQLKQIPQPEFVKNPMNLNTNSLQFKSTGWLN
TEKIYYDNSLIKPFSDYANELEAKLLQNICKNFSTNTFPIQSIILDSILPVLNFTLNV
SKRNFTRRIGDILVNAATGSGKTLAYSIPIVQTLFKRQINRLRCIIIVPTKLLINQVY
TTLTKLTQGTSLIVSIAKLENSLKDEHKKLSNLEPDILITTPGRLVDHLNMKSINLKN
LKFLIIDEADRLLNQSFQGWCPKLMSHLKTDKLDTLPGNVIKMIFSATLTTNTEKLNG
LNLYKPKLFLKQTDKLYQLPNKLNEFNINIPTAKSVYKPLILLYSICQFMAHSPIAAK
ILIFVKSNESSIRLSKLLQLICESRSQSSVLKNLQNLAVSINSVNSNNSKAENKKIVA
NFSHHSESAGITILITTDIMSRGIDINDITQVINYDPPMSSQQYVHRVGRTARANELG
SAYNLLVGRGERTFFDDLNKDLDRDGKSVQPLELDFTLLESDSELYTSSLESLKNYHN
NTAQA"
gene complement(697614..699431)
/gene="ZRG17"
/locus_tag="YNR039C"
/db_xref="GeneID:855775"
mRNA complement(697614..699431)
/gene="ZRG17"
/locus_tag="YNR039C"
/product="Zn(2+) transporter ZRG17"
/transcript_id="NM_001183216.1"
/db_xref="GI:296147802"
/db_xref="GeneID:855775"
CDS complement(697614..699431)
/gene="ZRG17"
/locus_tag="YNR039C"
/note="Endoplasmic reticulum hypothetical protein,
transcription is induced under conditions of zinc
deficiency; mutant phenotype suggests a role in uptake of
zinc"
/codon_start=1
/product="Zn(2+) transporter ZRG17"
/protein_id="NP_014437.1"
/db_xref="GI:6324367"
/db_xref="SGD:S000005322"
/db_xref="GeneID:855775"
/translation="METPQMNAIQEEDNLSPEVAFQTPKLNDSDASSFSLSNMNAVGN
VDGIPSQNRTFFASPRPSSLFYSAKEGNNSSSSIIYNPSFTFGENASSNANINEAALM
KGKGNEGRRQSLKYIPAPKLVPPPPRTRSPVRGISPDAGSSKRSSMTLDSPFNFTTST
LQPHQQTPPSSAASRTSFRKGHRYKHSSVSMNFFQEPEVKIPLNIAKSLPIPDFNDLL
SNLPWPKAYIQLSIAALQIFACLITFQVGHLYSWSNFITLSHFITYDIIGSLVIIFVE
NLSQFQVWFTGTITFPFGLNRIDVLLSFALAVSLCFVGLDLLFHIIEEFIVLFVESGS
SLTNNHDHDEINEQIPHSHIANANDSQNENITLWYSILMINLVLSTLSLYKTFYANKY
SNLKTKNPIITITYTAYLFIYPLLLDLLSSISDYLATLVISSLILWHGLTIARWTSTV
LLMGFSTTSLSNSALFNNNDSTDTTAHTQQVESKAAKEKPSVRPRSMSSLPIATKNTK
IRKTGFLNSAGFTENPTTIKNMIKDQIERLSEFKSRYILNYDDIVISKVNFTLYVVLI
KITMKGGSDDDELMLRLAIDKCIQTSIPTCETTIDIDRI"
gene 699690..700460
/locus_tag="YNR040W"
/db_xref="GeneID:855776"
mRNA 699690..700460
/locus_tag="YNR040W"
/product="hypothetical protein"
/transcript_id="NM_001183217.3"
/db_xref="GI:398365762"
/db_xref="GeneID:855776"
CDS 699690..700460
/locus_tag="YNR040W"
/note="hypothetical protein; the authentic, non-tagged
protein is detected in highly purified mitochondria in
high-throughput studies"
/codon_start=1
/product="hypothetical protein"
/protein_id="NP_014438.3"
/db_xref="GI:398365763"
/db_xref="SGD:S000005323"
/db_xref="GeneID:855776"
/translation="MTNMAAKNQFKGSSFTLAQLIEEVGRNGGKKPVFQYKVPRSIRW
ASTALAVVFLTYGAAYTDMSWRTAREVYGNATEEEKHSPWFKCKTFGPVALGVLPVIL
AAATKHVTSRLVTEMKYLPPLKNSTVPRCQLTRRTYLLGRPVSITREINELSKNKATK
IFTGVGSQGMEDKATFVFFTVDEKAPSFFNKFYIFSRSGSVVKNDARILDCFFNSVAE
NKLLNRSILTQILSHTSAKTLFHSGNSRSSIKNIVKPK"
gene complement(700541..701659)
/gene="COQ2"
/locus_tag="YNR041C"
/db_xref="GeneID:855778"
mRNA complement(700541..701659)
/gene="COQ2"
/locus_tag="YNR041C"
/product="4-hydroxybenzoate octaprenyltransferase"
/transcript_id="NM_001183218.3"
/db_xref="GI:398365766"
/db_xref="GeneID:855778"
CDS complement(700541..701659)
/gene="COQ2"
/locus_tag="YNR041C"
/EC_number="2.5.1.-"
/note="Para hydroxybenzoate: polyprenyl transferase,
catalyzes the second step in ubiquinone (coenzyme Q)
biosynthesis"
/codon_start=1
/product="4-hydroxybenzoate octaprenyltransferase"
/protein_id="NP_014439.3"
/db_xref="GI:398365767"
/db_xref="SGD:S000005324"
/db_xref="GeneID:855778"
/translation="MFIWQRKSILLGRSILGSGRVTVAGIIGSSRKRYTSSSSSSSSP
SSKESAPVFTSKELEVARKERLDGLGPFVSRLPKKWIPYAELMRLEKPVGTWLLYLPC
SWSILMGAMMQGATLSATAGMLGIFGVGALVMRGAGCTINDFLDRKLDQRVIRSVERP
IASGRVSPRRALVFLGAQTLVGMGVLSLLPAQCWWLGLASLPIVFTYPLFKRFTYYPQ
AALSACFNWGALLGFPAMGVMSWPTMIPLYLSSYLWCMTYDTIYAHQDKKFDIKAGIK
STALAWGPRTKSIMKAMSASQIALLAVAGLNSGLLWGPGFIGGLGVFAYRLFSMIKKV
DLDNPKNCWKYFNANINTGLYFTYALAVDYILRLFGFL"
gene 701895..703085
/gene="MVD1"
/locus_tag="YNR043W"
/gene_synonym="ERG19"
/db_xref="GeneID:855779"
mRNA 701895..703085
/gene="MVD1"
/locus_tag="YNR043W"
/gene_synonym="ERG19"
/product="diphosphomevalonate decarboxylase MVD1"
/transcript_id="NM_001183220.1"
/db_xref="GI:296147805"
/db_xref="GeneID:855779"
CDS 701895..703085
/gene="MVD1"
/locus_tag="YNR043W"
/gene_synonym="ERG19"
/EC_number="4.1.1.33"
/note="Mevalonate pyrophosphate decarboxylase, essential
enzyme involved in the biosynthesis of isoprenoids and
sterols, including ergosterol; acts as a homodimer"
/codon_start=1
/product="diphosphomevalonate decarboxylase MVD1"
/protein_id="NP_014441.1"
/db_xref="GI:6324371"
/db_xref="SGD:S000005326"
/db_xref="GeneID:855779"
/translation="MTVYTASVTAPVNIATLKYWGKRDTKLNLPTNSSISVTLSQDDL
RTLTSAATAPEFERDTLWLNGEPHSIDNERTQNCLRDLRQLRKEMESKDASLPTLSQW
KLHIVSENNFPTAAGLASSAAGFAALVSAIAKLYQLPQSTSEISRIARKGSGSACRSL
FGGYVAWEMGKAEDGHDSMAVQIADSSDWPQMKACVLVVSDIKKDVSSTQGMQLTVAT
SELFKERIEHVVPKRFEVMRKAIVEKDFATFAKETMMDSNSFHATCLDSFPPIFYMND
TSKRIISWCHTINQFYGETIVAYTFDAGPNAVLYYLAENESKLFAFIYKLFGSVPGWD
KKFTTEQLEAFNHQFESSNFTARELDLELQKDVARVILTQVGSGPQETNESLIDAKTG
LPKE"
gene 703699..705876
/gene="AGA1"
/locus_tag="YNR044W"
/db_xref="GeneID:855780"
mRNA 703699..705876
/gene="AGA1"
/locus_tag="YNR044W"
/product="Aga1p"
/transcript_id="NM_001183221.1"
/db_xref="GI:296147806"
/db_xref="GeneID:855780"
CDS 703699..705876
/gene="AGA1"
/locus_tag="YNR044W"
/note="Anchorage subunit of a-agglutinin of a-cells,
highly O-glycosylated protein with N-terminal secretion
signal and C-terminal signal for addition of GPI anchor to
cell wall, linked to adhesion subunit Aga2p via two
disulfide bonds"
/codon_start=1
/product="Aga1p"
/protein_id="NP_014442.1"
/db_xref="GI:6324372"
/db_xref="SGD:S000005327"
/db_xref="GeneID:855780"
/translation="MTLSFAHFTYLFTILLGLTNIALASDPETILVTITKTNDANGVV
TTTVSPALVSTSTIVQAGTTTLYTTWCPLTVSTSSAAEISPSISYATTLSRFSTLTLS
TEVCSHEACPSSSTLPTTTLSVTSKFTSYICPTCHTTAISSLSEVGTTTVVSSSAIEP
SSASIISPVTSTLSSTTSSNPTTTSLSSTSTSPSSTSTSPSSTSTSSSSTSTSSSSTS
TSSSSTSTSPSSTSTSSSLTSTSSSSTSTSQSSTSTSSSSTSTSPSSTSTSSSSTSTS
PSSKSTSASSTSTSSYSTSTSPSLTSSSPTLASTSPSSTSISSTFTDSTSSLGSSIAS
SSTSVSLYSPSTPVYSVPSTSSNVATPSMTSSTVETTVSSQSSSEYITKSSISTTIPS
FSMSTYFTTVSGVTTMYTTWCPYSSESETSTLTSMHETVTTDATVCTHESCMPSQTTS
LITSSIKMSTKNVATSVSTSTVESSYACSTCAETSHSYSSVQTASSSSVTQQTTSTKS
WVSSMTTSDEDFNKHATGKYHVTSSGTSTISTSVSEATSTSSIDSESQEQSSHLLSTS
VLSSSSLSATLSSDSTILLFSSVSSLSVEQSPVTTLQISSTSEILQPTSSTAIATISA
STSSLSATSISTPSTSVESTIESSSLTPTVSSIFLSSSSAPSSLQTSVTTTEVSTTSI
SIQYQTSSMVTISQYMGSGSQTRLPLGKLVFAIMAVACNVIFS"
gene 706139..707608
/gene="PET494"
/locus_tag="YNR045W"
/db_xref="GeneID:855781"
mRNA 706139..707608
/gene="PET494"
/locus_tag="YNR045W"
/product="Pet494p"
/transcript_id="NM_001183222.3"
/db_xref="GI:398365784"
/db_xref="GeneID:855781"
CDS 706139..707608
/gene="PET494"
/locus_tag="YNR045W"
/note="Mitochondrial translational activator specific for
the COX3 mRNA, acts together with Pet54p and Pet122p;
located in the mitochondrial inner membrane"
/codon_start=1
/product="Pet494p"
/protein_id="NP_014443.3"
/db_xref="GI:398365785"
/db_xref="SGD:S000005328"
/db_xref="GeneID:855781"
/translation="MHLKKGKRSISTVWRLLWKRFYSVNSKTNMHFSRSRKKPVTNFT
RTNGLLLSCNGDTFPYLRTLWRYFNAPGNLMFVTTNIVAFMGIVTYNTLVTISSERAF
EEQMMAAQVSLAKQREELETTALSLPRDIELRGEEDDIKWEQPDVAHVREDPLVEEQN
AKLDTPIKQYTLGDLILNKRENVTDYDSQRAKASIFHMLYAYMLYRDVIQPTTMTQNN
NSEEWRREVELLTKGKEVQGTHRRIDVFYDLWNKNFDKIVTSPEKVQNFQLPNWSKYP
TILKFICTELHDNSLKTLGEFKQFYGKVRSNEVKKLLGLWLYDHSFLFPHNIYDNRTE
EDFYDILINDSMQDNRIFQKYSSIVMNPYNERTQLFFPNVNSPSVNKPVPSISLETYT
RLLKGYINLQETGCKYDYNDNIFKLISILKLNCFLQRNKKKHAGPTVRILLPRDEDRS
QILGTISQAEKRTCYQILSKNRDVVALLKRISDIQADSS"
gene 707788..708195
/gene="TRM112"
/locus_tag="YNR046W"
/db_xref="GeneID:855782"
mRNA 707788..708195
/gene="TRM112"
/locus_tag="YNR046W"
/product="Trm112p"
/transcript_id="NM_001183223.1"
/db_xref="GI:296147808"
/db_xref="GeneID:855782"
CDS 707788..708195
/gene="TRM112"
/locus_tag="YNR046W"
/note="Protein involved in methylation of tRNA, rRNA, and
translation factors; subunit of tRNA methyltransferase
(MTase) complexes in combination with Trm9p and Trm11p;
interacts with and stabilizes 18S rRNA methyltransferase
Bud23p; subunit of complex with Mtq2p that methylates
Sup45p (eRF1) in the ternary complex eRF1-eRF3-GTP;
deletion confers resistance to zymocin; relative
distribution to the nucleus increases upon DNA replication
stress"
/codon_start=1
/product="Trm112p"
/protein_id="NP_014444.1"
/db_xref="GI:6324374"
/db_xref="SGD:S000005329"
/db_xref="GeneID:855782"
/translation="MKFLTTNFLKCSVKACDTSNDNFPLQYDGSKCQLVQDESIEFNP
EFLLNIVDRVDWPAVLTVAAELGNNALPPTKPSFPSSIQELTDDDMAILNDLHTLLLQ
TSIAEGEMKCRNCGHIYYIKNGIPNLLLPPHLV"
gene 708523..711204
/gene="FPK1"
/locus_tag="YNR047W"
/db_xref="GeneID:855783"
mRNA 708523..711204
/gene="FPK1"
/locus_tag="YNR047W"
/product="Fpk1p"
/transcript_id="NM_001183224.1"
/db_xref="GI:296147809"
/db_xref="GeneID:855783"
CDS 708523..711204
/gene="FPK1"
/locus_tag="YNR047W"
/EC_number="2.7.11.1"
/note="Ser/Thr protein kinase that regulates the putative
phospholipid translocases Lem3p-Dnf1p/Dnf2p;
phosphorylates and inhibits upstream inhibitory kinase,
Ypk1p; localizes to the cytoplasm, early endosome/TGN
compartments, and plasma membrane"
/codon_start=1
/product="Fpk1p"
/protein_id="NP_014445.1"
/db_xref="GI:6324375"
/db_xref="SGD:S000005330"
/db_xref="GeneID:855783"
/translation="MAGHHHEHEQERDHEQEHEHDSLQRPTTGSERTRSISFSKLLTR
SWKRNASSSNNMSVSSVNLYSDPENSRESDHNNSGSEGQSSRFSKLKSMFQSGNSSKN
ASAHNSSQSSLEGDSASSSSKLRYVKPMTSVANASPASPPLSPTIPETDVLQTPKMVH
IDQHEHEREHSNCGSPIMLSSSSFSPTVARTGTGRRRSPSTPIMPSQNSNNSSSTSAI
RPNNYRHHSGSQGFSSNNPFRERAGTVRSSNPYFAYQGLPTHAMSSHDLDEGFQPYAN
GSGIHFLSTPTSKTNSLTNTKNLSNLSLNEIKENEEVQEFNNEDFFFHDIPKDLSLKD
TLNGSPSRGSSKSPTITQTFPSIIVGFDNEYEEDNNNDKHDEKEEQQTTTDNKTRNLS
PTKQNGKATHPRIKIPLRRAASEPNGLQLASATSPTSSSARKTSGSSNINDKIPGQSV
PPPNSFFPQEPSPKISDFPEPRRSRRLRTKSFSNKFQDIMVGPQSFEKIRLLGQGDVG
KVFLVREKKTNRVYALKVLSKDEMIKRNKIKRVLTEQEILATSNHPFIVTLYHSFQSE
DYLYLCMEYCMGGEFFRALQTRKTKCICEDDARFYASEVTAALEYLHLLGFIYRDLKP
ENILLHQSGHIMLSDFDLSIQAKDSKVPVVKGSAQSTLVDTKICSDGFRTNSFVGTEE
YIAPEVIRGNGHTAAVDWWTLGILIYEMLFGFTPFKGDNTNETFTNILKNEVSFPNNN
EISRTCKDLIKKLLTKNESKRLGCKMGAADVKKHPFFKKVQWSLLRNQEPPLIPVLSE
DGYDFAKLSSNKKRQTSQDSHKHLDEQEKNMFEERVEYDDEVSEDDPFHDFNSMSLME
QDNNSMIYGNTNSYGKIAYTPNSNRSRSNSHRTFFKR"
gene 711630..712811
/locus_tag="YNR048W"
/gene_synonym="CRF1"
/db_xref="GeneID:855784"
mRNA 711630..712811
/locus_tag="YNR048W"
/gene_synonym="CRF1"
/product="hypothetical protein"
/transcript_id="NM_001183225.3"
/db_xref="GI:398365796"
/db_xref="GeneID:855784"
CDS 711630..712811
/locus_tag="YNR048W"
/gene_synonym="CRF1"
/note="Protein that interacts with phospholipid
translocase (flippase) Dnf3p; YNR048W has a paralog,
CDC50, that arose from the whole genome duplication"
/codon_start=1
/product="hypothetical protein"
/protein_id="NP_014446.3"
/db_xref="GI:398365797"
/db_xref="SGD:S000005331"
/db_xref="GeneID:855784"
/translation="MGLILRWKEKKQLSSKQNAQKSRKPANTSFRQQRLKAWQPILSP
QSVLPLLILMACVFAPIGIGLVVSTISVQRLVVNYTECDALAPAKHFETIPSEYVDYH
FSKKVAVQPQWMVLTDPELGNQTCRIQFEVPNHIKKSTYVYYRLTNFNQNYREYVQSL
DLDQLKGKALIGNDLDPNCDPLRTVENKTIFPCGLIANSMFNDTFGTTLTGVNDTADY
LLTTKGIAWDTDSHRYGKTEYNASDIVPPPNWAKLFPNGYTDDNIPDLQNWEQFKIWM
RTAALPNFYKLAMKNETNGLGKGIYIADIELNYPVRSFYGTKSFVLTTNSIIGAGNEA
LGIVYLIVAGIATLFAILFLIKVIFKPRPMHDHSYLNFENSDTPFDESSVVSIPLREI
L"
gene complement(713023..713655)
/gene="MSO1"
/locus_tag="YNR049C"
/db_xref="GeneID:855785"
mRNA complement(713023..713655)
/gene="MSO1"
/locus_tag="YNR049C"
/product="Mso1p"
/transcript_id="NM_001183226.3"
/db_xref="GI:398365804"
/db_xref="GeneID:855785"
CDS complement(713023..713655)
/gene="MSO1"
/locus_tag="YNR049C"
/note="Probable component of the secretory vesicle docking
complex; acts at a late step in secretion; shows genetic
and physical interactions with Sec1p; required for
prospore membrane formation during sporulation;
relocalizes from bud neck to nucleus upon DNA replication
stress"
/codon_start=1
/product="Mso1p"
/protein_id="NP_014447.3"
/db_xref="GI:398365805"
/db_xref="SGD:S000005332"
/db_xref="GeneID:855785"
/translation="MMSQVSHSQEGSGRFWNKFKSSTKSLSTSLAHLSIKAEKDGDTV
NTTLVHKGLVKFYENQHPFQGFPGWLGEKEDLPNERKILDTQVKHDMKKQNSRHFSPS
FSNRRKASSEDPMGTPSSNGNTPEYTPASKSFQDIYNNHTSSSSATPRRASSRPTRPS
AGQEFRASLGRSKTSNSFNTSSTPTPPPDASSGVMAMKDRLKRRNNDYGF"
gene complement(714048..715388)
/gene="LYS9"
/locus_tag="YNR050C"
/gene_synonym="LYS13"
/db_xref="GeneID:855786"
mRNA complement(714048..715388)
/gene="LYS9"
/locus_tag="YNR050C"
/gene_synonym="LYS13"
/product="saccharopine dehydrogenase (NADP+,
L-glutamate-forming)"
/transcript_id="NM_001183227.1"
/db_xref="GI:296147812"
/db_xref="GeneID:855786"
CDS complement(714048..715388)
/gene="LYS9"
/locus_tag="YNR050C"
/gene_synonym="LYS13"
/EC_number="1.5.1.10"
/note="Saccharopine dehydrogenase (NADP+,
L-glutamate-forming); catalyzes the formation of
saccharopine from alpha-aminoadipate 6-semialdehyde, the
seventh step in lysine biosynthesis pathway; exhibits
genetic and physical interactions with TRM112"
/codon_start=1
/product="saccharopine dehydrogenase (NADP+,
L-glutamate-forming)"
/protein_id="NP_014448.1"
/db_xref="GI:6324378"
/db_xref="SGD:S000005333"
/db_xref="GeneID:855786"
/translation="MGKNVLLLGSGFVAQPVIDTLAANDDINVTVACRTLANAQALAK
PSGSKAISLDVTDDSALDKVLADNDVVISLIPYTFHPNVVKSAIRTKTDVVTSSYISP
ALRELEPEIVKAGITVMNEIGLDPGIDHLYAVKTIDEVHRAGGKLKSFLSYCGGLPAP
EDSDNPLGYKFSWSSRGVLLALRNSAKYWKDGKIETVSSEDLMATAKPYFIYPGYAFV
CYPNRDSTLFKDLYHIPEAETVIRGTLRYQGFPEFVKALVDMGMLKDDANEIFSKPIA
WNEALKQYLGAKSTSKEDLIASIDSKATWKDDEDRERILSGFAWLGLFSDAKITPRGN
ALDTLCARLEELMQYEDNERDMVVLQHKFGIEWADGTTETRTSTLVDYGKVGGYSSMA
ATVGYPVAIATKFVLDGTIKGPGLLAPYSPEINDPIMKELKDKYGIYLKEKTVA"
gene 716120..716284
/locus_tag="snR49"
/db_xref="GeneID:9164966"
ncRNA 716120..716284
/locus_tag="snR49"
/ncRNA_class="snoRNA"
/product="SNR49"
/note="H/ACA box small nucleolar RNA (snoRNA); guides
pseudouridylation of large subunit (LSU) rRNA at position
U990 and small subunit (SSU) rRNA at positions U120, U211,
and U302"
/db_xref="SGD:S000007460"
/db_xref="GeneID:9164966"
gene complement(716780..718327)
/gene="BRE5"
/locus_tag="YNR051C"
/db_xref="GeneID:855787"
mRNA complement(716780..718327)
/gene="BRE5"
/locus_tag="YNR051C"
/product="Bre5p"
/transcript_id="NM_001183228.1"
/db_xref="GI:296147813"
/db_xref="GeneID:855787"
CDS complement(716780..718327)
/gene="BRE5"
/locus_tag="YNR051C"
/note="Ubiquitin protease cofactor, forms deubiquitination
complex with Ubp3p that coregulates anterograde and
retrograde transport between the endoplasmic reticulum and
Golgi compartments; null is sensitive to brefeldin A"
/codon_start=1
/product="Bre5p"
/protein_id="NP_014449.1"
/db_xref="GI:6324379"
/db_xref="SGD:S000005334"
/db_xref="GeneID:855787"
/translation="MGVTVQDICFAFLQNYYERMRTDPSKLAYFYASTAELTHTNYQS
KSTNEKDDVLPTVKVTGRENINKFFSRNDAKVRSLKLKLDTIDFQYTGHLHKSILIMA
TGEMFWTGTPVYKFCQTFILLPSSNGSTFDITNDIIRFISNSFKPYVLTDASLSQSNE
ENSVSAVEEDKIRHESGVEKEKEKEKSPEISKPKAKKETVKDTTAPTESSTQEKPIVD
HSQPRAIPVTKESKIHTETVPSSTKGNHKQDEVSTEELGNVTKLNEKSHKAEKKAAPI
KTKEGSVEAINAVNNSSLPNGKEVSDEKPVPGGVKEAETEIKPIEPQVSDAKESGNNA
STPSSSPEPVANPPKMTWASKLMNENSDRISKNNTTVEYIRPETLPKKPTERKFEMGN
RRDNASANSKNKKKPVFSTVNKDGFYPIYIRGTNGLREEKLRSALEKEFGKVMRITAA
DNFAVVDFETQKSQIDALEKKKKSIDGIEVCLERKTVKKPTSNNPPGIFTNGTRSHRK
QPLKRKD"
gene complement(719346..720647)
/gene="POP2"
/locus_tag="YNR052C"
/gene_synonym="CAF1"
/db_xref="GeneID:855788"
mRNA complement(719346..720647)
/gene="POP2"
/locus_tag="YNR052C"
/gene_synonym="CAF1"
/product="Pop2p"
/transcript_id="NM_001183229.3"
/db_xref="GI:398365812"
/db_xref="GeneID:855788"
CDS complement(719346..720647)
/gene="POP2"
/locus_tag="YNR052C"
/gene_synonym="CAF1"
/EC_number="3.1.13.4"
/note="RNase of the DEDD superfamily, subunit of the
Ccr4-Not complex that mediates 3' to 5' mRNA
deadenylation"
/codon_start=1
/product="Pop2p"
/protein_id="NP_014450.3"
/db_xref="GI:398365813"
/db_xref="SGD:S000005335"
/db_xref="GeneID:855788"
/translation="MQSMNVQPRVLAVGGEQFFSQRQASEQHQQQNMGPQVYSPKVNR
ARMFPQGMPVNTINGSVNQEMNNAYLLKQKNEPLLTQQQQQQQQQQQPFNIGTPVSVA
SLPPGLNVLQQQQQQQQQQQQQQQGVGLNRPLASQLPKHLTNQSMPPIFLPPPNYLFV
RDVWKSNLYSEFAVIRQLVSQYNHVSISTEFVGTLARPIGTFRSKVDYHYQTMRANVD
FLNPIQLGLSLSDANGNKPDNGPSTWQFNFEFDPKKEIMSTESLELLRKSGINFEKHE
NLGIDVFEFSQLLMDSGLMMDDSVTWITYHAAYDLGFLINILMNDSMPNNKEDFEWWV
HQYMPNFYDLNLVYKIIQEFKNPQLQQSSQQQQQQQYSLTTLADELGLPRFSIFTTTG
GQSLLMLLSFCQLSKLSMHKFPNGTDFAKYQGVIYGIDGDQ"
gene complement(721120..723112)
/gene="NOG2"
/locus_tag="YNR053C"
/gene_synonym="NUG2"
/db_xref="GeneID:855789"
mRNA complement(join(721120..721770,722303..723112))
/gene="NOG2"
/locus_tag="YNR053C"
/gene_synonym="NUG2"
/product="Nog2p"
/transcript_id="NM_001183230.1"
/db_xref="GI:296147815"
/db_xref="GeneID:855789"
CDS complement(join(721120..721770,722303..723112))
/gene="NOG2"
/locus_tag="YNR053C"
/gene_synonym="NUG2"
/note="Putative GTPase that associates with pre-60S
ribosomal subunits in the nucleolus and is required for
their nuclear export and maturation"
/codon_start=1
/product="Nog2p"
/protein_id="NP_014451.1"
/db_xref="GI:6324381"
/db_xref="SGD:S000005336"
/db_xref="GeneID:855789"
/translation="MGTGKKEKSRRIREGDTKDGNLRVKGENFYRDSKRVKFLNMYTS
GKEIRNKKGNLIRAASFQDSTIPDARVQPDRRWFGNTRVISQDALQHFRSALGETQKD
TYQVLLRRNKLPMSLLEEKDADESPKARILDTESYADAFGPKAQRKRPRLAASNLEDL
VKATNEDITKYEEKQVLDATLGLMGNQEDKENGWTSAAKEAIFSKGQSKRIWNELYKV
IDSSDVVIHVLDARDPLGTRCKSVEEYMKKETPHKHLIYVLNKCDLVPTWVAAAWVKH
LSKERPTLAFHASITNSFGKGSLIQLLRQFSQLHTDRKQISVGFIGYPNTGKSSIINT
LRKKKVCQVAPIPGETKVWQYITLMKRIFLIDCPGIVPPSSKDSEEDILFRGVVRVEH
VTHPEQYIPGVLKRCQVKHLERTYEISGWKDATEFIEILARKQGRLLKGGEPDESGVS
KQILNDFNRGKIPWFVLPPEKEGEEKPKKKEVEKTA"
gene complement(721938..722211)
/locus_tag="snR191"
/db_xref="GeneID:9164970"
ncRNA complement(721938..722211)
/locus_tag="snR191"
/ncRNA_class="snoRNA"
/product="SNR191"
/note="H/ACA box small nucleolar RNA (snoRNA); guides
pseudouridylation of large subunit (LSU) rRNA at positions
U2258 and U2260; encoded within the intron of
NOG2/YNR053C"
/db_xref="SGD:S000029463"
/db_xref="GeneID:9164970"
gene complement(723356..724306)
/gene="ESF2"
/locus_tag="YNR054C"
/gene_synonym="ABT1"
/db_xref="GeneID:855790"
mRNA complement(723356..724306)
/gene="ESF2"
/locus_tag="YNR054C"
/gene_synonym="ABT1"
/product="Esf2p"
/transcript_id="NM_001183231.1"
/db_xref="GI:296147816"
/db_xref="GeneID:855790"
CDS complement(723356..724306)
/gene="ESF2"
/locus_tag="YNR054C"
/gene_synonym="ABT1"
/note="Essential nucleolar protein involved in pre-18S
rRNA processing; binds to RNA and stimulates ATPase
activity of Dbp8; involved in assembly of the small
subunit (SSU) processome"
/codon_start=1
/product="Esf2p"
/protein_id="NP_014452.1"
/db_xref="GI:6324382"
/db_xref="SGD:S000005337"
/db_xref="GeneID:855790"
/translation="MSEKVNSDFEDFSSDEETDQHNVLIQTKKKISSKDDIFSKKVED
IESENESDIEEEQKQEEKEDVEQPDKENGEKLDREVEEQASSTTSLDLKTEKLRQLVK
SKAAKKSKHKTGVVYFSSIPPYMKPAKMRQILTRFGEVDRLFLKKEDDQKYKQRVKGG
GNKKNKYEEGWAEFIRKRDAKLCAETLNGNIIGGKKGTFYHDDILNVKYLPGFKWADL
TEQIARENDIRQAKLEMEISQANKLNAEFIRNVEQSKMIQNIKNSRKRAGKEGESADS
HPHREFKQRRVETSRANAPSDIKQQSSGSKDLGNVLTNLL"
gene complement(726134..726217)
/locus_tag="tL(UAA)N"
/db_xref="GeneID:855791"
tRNA complement(726134..726217)
/locus_tag="tL(UAA)N"
/product="tRNA-Leu"
/note="Leucine tRNA (tRNA-Leu), predicted by tRNAscan-SE
analysis"
/db_xref="SGD:S000006653"
/db_xref="GeneID:855791"
LTR 726234..726574
/note="Ty3 LTR"
/db_xref="SGD:S000007147"
LTR complement(726614..726945)
/note="Ty1 LTR"
/db_xref="SGD:S000007144"
LTR complement(727363..727661)
/note="Ty1 LTR"
/db_xref="SGD:S000007145"
gene complement(728426..730186)
/gene="HOL1"
/locus_tag="YNR055C"
/db_xref="GeneID:855792"
mRNA complement(728426..730186)
/gene="HOL1"
/locus_tag="YNR055C"
/product="Hol1p"
/transcript_id="NM_001183232.3"
/db_xref="GI:398365828"
/db_xref="GeneID:855792"
CDS complement(728426..730186)
/gene="HOL1"
/locus_tag="YNR055C"
/note="Putative transporter in the major facilitator
superfamily; member of the 12-spanner drug:H(+) antiporter
DHA1 family; mutations in membrane-spanning domains permit
cation and histidinol uptake"
/codon_start=1
/product="Hol1p"
/protein_id="NP_014453.3"
/db_xref="GI:398365829"
/db_xref="SGD:S000005338"
/db_xref="GeneID:855792"
/translation="MDKYTNRDHPDYIPGTFNIYSSQNLENGIIYESKLKKTSSGVVL
IPQPSYSPNDPLNWSSWRKLAHFGLMAFITAFTAATSNDAGAAQDSLNEIYGISYDSM
NTGAGVLFLGIGWSTLFLAPFANLYGRKITYIVCTTLGLFGALWFALAKRTSDTIWSQ
LFVGISESCAEAQVQLSLSDIFFQHQLGSVLTVYIMCTSIGTFLGPLIAGYISAFTNF
RWVGWVAVIISGGLLITIIFGCEETYFDRGQYMTPLTSCQSGYEDGTTLQNSDNTAVS
RRKRHLDAKLSTPGAMGEKGVDLSETAEFEVNNEEEVTIPETRELIDGSKEHLKPYPK
RVAILTKATNLKGYGFKQYFKYLKINLRMFLFPPVWLSGMFWGIQDVFLTFYLTTQES
AYYEPPWNYSDFGVAIMNVPTLIGAVIGCICAGIVSDYFVLWMARHNRGILEAEFRLY
FSIATAIIGPAGLLMFGIGTARQWPWQAIYVGLGFVGFAWGCSGDIAMAYLMDCYPDM
VLEGMVCTAIINNTISCIFTFTCSDWLAASGTENTYIALAVINFGITAFALPMYYYGK
RIRLWTKRWYLQSVNLRDGV"
gene complement(731618..733303)
/gene="BIO5"
/locus_tag="YNR056C"
/db_xref="GeneID:855793"
mRNA complement(731618..733303)
/gene="BIO5"
/locus_tag="YNR056C"
/product="Bio5p"
/transcript_id="NM_001183233.3"
/db_xref="GI:398365832"
/db_xref="GeneID:855793"
CDS complement(731618..733303)
/gene="BIO5"
/locus_tag="YNR056C"
/note="Putative transmembrane protein involved in the
biotin biosynthesis pathway; responsible for uptake of
7-keto 8-aminopelargonic acid; BIO5 is in a cluster of 3
genes (BIO3, BIO4, and BIO5) that mediate biotin
synthesis"
/codon_start=1
/product="Bio5p"
/protein_id="NP_014454.3"
/db_xref="GI:398365833"
/db_xref="SGD:S000005339"
/db_xref="GeneID:855793"
/translation="MNRVGAVFLFVYERNFFLSIVPDRHRTEIRMSSSERSEVKFDKH
FNWWSLLGIAFSLSCSWVGISASMAVGIASGGPLLIIYGLIIAAFFSLMCGISLGDFA
AILPNSSGGSFWVLKMLEQESVTLKTPEYEDPSDDDEEVFLENYCQTFNVEVSSKFQK
VSSMVVGLLNYFGAIFTTASICSSLSMSCIGIHKLLHPDYELKHWHVFVGYECINAVL
TLFNIYSTPLPYISQFGLYTSLLSFAMTFIICIVSRSDNTVDPWPKASNIFGSFDNQT
GWNSSGMAFVVGLVNPIWAFVGIDSATHMIDEVGYSKSRFLVPKVIITTIIVGFVTSF
IYCVGLFFCITDQTAVVESILPIVEIFYQATGNRNLSVFLQCMCITTGFVSGIASGTW
QSRILQSFGKSYAPFYKEGSLGNKSLKKLAVLTPGFKSPLYAHFLSQICVTIIGCIFM
GSSTAFNAIITACITLLLMSYAVPSFIFLFVIKKEKFIHRIESDVNCVSRPNRRRMSM
IPHIICILWTLFCLVFLSFPYTLPVTAGNMNYTSVVYAVVFCIISIVVFPTCI"
gene complement(733356..734069)
/gene="BIO4"
/locus_tag="YNR057C"
/db_xref="GeneID:855794"
mRNA complement(733356..734069)
/gene="BIO4"
/locus_tag="YNR057C"
/product="dethiobiotin synthase"
/transcript_id="NM_001183234.1"
/db_xref="GI:296147819"
/db_xref="GeneID:855794"
CDS complement(733356..734069)
/gene="BIO4"
/locus_tag="YNR057C"
/EC_number="6.3.3.3"
/note="Dethiobiotin synthetase, catalyzes the third step
in the biotin biosynthesis pathway; BIO4 is in a cluster
of 3 genes (BIO3, BIO4, and BIO5) that mediate biotin
synthesis; expression appears to be repressed at low iron
levels"
/codon_start=1
/product="dethiobiotin synthase"
/protein_id="NP_014455.1"
/db_xref="GI:6324385"
/db_xref="SGD:S000005340"
/db_xref="GeneID:855794"
/translation="MNSKSQQQEQQPIVFVTGTDTDVGKTFVSTLLVHKWKAAYWKPV
QTGIESDQGDSETLKNFKIAASTWQPPIFTPTYALQKPLSPLQAMEYEPNVDIRLLDF
VVPEEWSAENPLVVEGAGGVCVPITRKLEITTDLIKHLIETSGHPVYVVVVARSGLGT
LNHTLLTWNHLCDNGLRSHLFGVILNGEPNEGNVQALKKFGVNIMAQVAQCTTAHDQD
MELHELPSVESLMTQQDVE"
gene 734291..735733
/gene="BIO3"
/locus_tag="YNR058W"
/db_xref="GeneID:855795"
mRNA 734291..735733
/gene="BIO3"
/locus_tag="YNR058W"
/product="adenosylmethionine-8-amino-7-oxononanoate
transaminase"
/transcript_id="NM_001183235.1"
/db_xref="GI:296147820"
/db_xref="GeneID:855795"
CDS 734291..735733
/gene="BIO3"
/locus_tag="YNR058W"
/EC_number="2.6.1.62"
/note="7,8-diamino-pelargonic acid aminotransferase
(DAPA), catalyzes the second step in the biotin
biosynthesis pathway; BIO3 is in a cluster of 3 genes
(BIO3, BIO4, and BIO5) that mediate biotin synthesis"
/codon_start=1
/product="adenosylmethionine-8-amino-7-oxononanoate
transaminase"
/protein_id="NP_014456.1"
/db_xref="GI:6324386"
/db_xref="SGD:S000005341"
/db_xref="GeneID:855795"
/translation="MSQEISYTPDVAELLDFDKKHIWHPYTSLSSPLNVYPVKSAHGC
KLVLDTDSPVDVEVIDAMSSWWCVIHGYNNPELNEALTKQMLKFSHVLLGGFTHKGAV
NLVQKLLKVIDEPSLQYCFLADSGSVAVEVALKMALQSNMSGEATKNRTKFLTIKNGY
HGDTFGAMSVCDPENSMHHIYNDRLSENIFAQAPSIVDGLPTSQNGFEDHWNAEEVTD
LKKQFELHSDKICAVILEPILQGAGGLRPYHPQFLIEVQKLCNQYDVLFIMDEIATGF
GRTGEIFAFKHCQKYQDQHGISPSDQIKVVPDILCVGKGLTSGYMTMSAVVVNDKVAS
RISSPNSPTGGCFMHGPTFMGNALACSVAEKSMDILLRGEWRKQVSAIENQIYRELYQ
YIKNPDNGLIGTVVKRVSVIGAVGIVELYKKTDPEWFQKKFISKGVHIRPFNCLCYIM
PPYVITTEELTKVNQVLIEVLHEWKSHINQ"
gene 736803..738545
/gene="MNT4"
/locus_tag="YNR059W"
/db_xref="GeneID:855796"
mRNA 736803..738545
/gene="MNT4"
/locus_tag="YNR059W"
/product="Mnt4p"
/transcript_id="NM_001183236.3"
/db_xref="GI:398365842"
/db_xref="GeneID:855796"
CDS 736803..738545
/gene="MNT4"
/locus_tag="YNR059W"
/EC_number="2.4.1.-"
/note="Putative alpha-1,3-mannosyltransferase, not
required for protein O-glycosylation"
/codon_start=1
/product="Mnt4p"
/protein_id="NP_014457.3"
/db_xref="GI:398365843"
/db_xref="SGD:S000005342"
/db_xref="GeneID:855796"
/translation="MVLRIRRIKKLAPLIFTSLLSLIVLFRVYRQYPFSDHFETRRED
DRSGNVHCFSRLRQIEEYEKPELTSKFYEPNRWKSFISYVTRSRKDVKTVSRSLSNLD
LYQKCSKEIRADQDISLLHSIETKLFPYINFTALNSEQSHNFWPVHTRFDGTKYRGQV
LQFSSENNSFIGTSPIEFKASEPFWENWLNSALQRNSKGVVMSVSEYLVADTIRLIRV
LRLLNNSLPIEIVHKSDLHESSQQLLIAAARESGSLNYPPQELWFLDVKDMLNDEYLA
RFKRFSNKWLAITFCSFQIPIFLDSDTVPFVPLDTLYEIDGFKRTGTLFFKDRSFPTS
KLSPLQVKVLKQIINNSLDVSSDSEQGFEILKHNLNDEMAIDAIEALIFKKQKHYMDS
GLVIFDKQKHFFCLPIAIMLQFSPIQEFFHGDKEWFWLSLFISKKEFTFYPIEASNVG
RLEKPETLESSTICSTQLSHTDVYGNLLWLNGGLSVCKKNCWNYDFTKRKEIAAKYKS
VDELRNYYQSPVKLEAVIIPDVSKSPWSQQSECVMYSYCTHYRKGQYGKLIEFTDSQK
KYYEKVVELWNKVV"
gene 739951..742110
/gene="FRE4"
/locus_tag="YNR060W"
/db_xref="GeneID:855797"
mRNA 739951..742110
/gene="FRE4"
/locus_tag="YNR060W"
/product="Fre4p"
/transcript_id="NM_001183237.1"
/db_xref="GI:296147822"
/db_xref="GeneID:855797"
CDS 739951..742110
/gene="FRE4"
/locus_tag="YNR060W"
/EC_number="1.16.1.7"
/note="Ferric reductase, reduces a specific subset of
siderophore-bound iron prior to uptake by transporters;
expression induced by low iron levels"
/codon_start=1
/product="Fre4p"
/protein_id="NP_014458.1"
/db_xref="GI:6324388"
/db_xref="SGD:S000005343"
/db_xref="GeneID:855797"
/translation="MLLVHIISFLLFFQLSAAKAPPSKTSLINTHERRSIYSCYVGLR
KETWGFNGSAICRYEPAIQSMLYCLYEDTHEKGYSNKTLEKGFEEMRQFCYTPKFLNM
TDAEFYTSLDNGTYYIQDQPKAGINITYPIRLNTTLRKAYYDAYYGYYYNHDIPYYFG
GIICAYFVGVMLLAGLIRFLNYTPIKKIMFQQKLVNYVRGYTTLPTLYEKHAEPFSYL
KVITGYLPTRFETLVILGYLILHTIFMAYKYQYDPYHIIFAAHRAEVAHFVAYRSGIL
SFAHLPLIVLFAGRNNFLQLISGLKHTSFIVFHKWLGRMMFLDAIIHAAGFTNYYLYY
KKWNTVRLRVYWKFGIATTCLAGMLIFFSIAAFRRHYYETFMALHIVFAALFLYTCWE
HVTNFSGIEWIYAAIAIWGVDRIVRITRIALLGFPKADLQLVGSDLVRVTVKKPKKFW
KAKPGQYVFVSFLRPLCFWQSHPFTVMDSCVNDRELVIVLKAKKGVTKLVRNFVERKG
GKASMRLAIEGPYGSKSTAHRFDNVLLLAGGSGLPGPISHALELGKTTAASGKNFVQL
VIAVRGLDMLNACKKELMALKGLNVQVHIYNSKQELASAEKISSNEVKNGETTAEKAP
SSLSNSEKAPSESENTELPLSLNDTSISDLEFATFHVGRPNVEEILNESVNHSGSLAV
VCCGPPIFVDTARNQTAKAVIRNPSRMIEYLEEYQAW"
gene complement(742881..743540)
/locus_tag="YNR061C"
/db_xref="GeneID:855798"
mRNA complement(742881..743540)
/locus_tag="YNR061C"
/product="hypothetical protein"
/transcript_id="NM_001183238.1"
/db_xref="GI:296147823"
/db_xref="GeneID:855798"
CDS complement(742881..743540)
/locus_tag="YNR061C"
/note="hypothetical protein; relocalizes from vacuole to
cytoplasm upon DNA replication stress"
/codon_start=1
/product="hypothetical protein"
/protein_id="NP_014459.1"
/db_xref="GI:6324389"
/db_xref="SGD:S000005344"
/db_xref="GeneID:855798"
/translation="MLKLTTTSVTFHVLRYFQLGLSVTNLLLASFAIITNYKVDRILR
LSLAVSIISSVYFGIVRFLPVLLIFVMEIVQTVLWFTAFVTLASKFGSMSCSSMPRGI
NFDYSGSCKIAKIDILPEAVLFILFLATTYASYITVLSQAKENGSSTRSVLKACVKAL
RDTVDRLETSLEESEPLLDLEVQEDARTETESIEDSTDSEDNANIEQEKVIDGSIEHS
S"
gene complement(744360..745343)
/locus_tag="YNR062C"
/db_xref="GeneID:855799"
mRNA complement(744360..745343)
/locus_tag="YNR062C"
/product="hypothetical protein"
/transcript_id="NM_001183239.3"
/db_xref="GI:398365856"
/db_xref="GeneID:855799"
CDS complement(744360..745343)
/locus_tag="YNR062C"
/note="Putative membrane hypothetical protein"
/codon_start=1
/product="hypothetical protein"
/protein_id="NP_014460.3"
/db_xref="GI:398365857"
/db_xref="SGD:S000005345"
/db_xref="GeneID:855799"
/translation="MSIAQDRGIVFKLLSIYRAAAGIFMALAQLIVIFFGYCDFKIKG
YRIASYNAPTFASSFIILAVCLLLVVVLENPEVKVTNSENSLFSALKQFFRVERKKLI
SCLILLWSMFLSSFIMSEVVYFMPLFLTLHVNWDTKFQGIAFMVASILGVTGSYFAPK
LINVGCSCGRAKDGGLEESDTTGSETVEVKKKDSLYSGQVFLSIFALFVSLLGQAFMI
GASEALKHKSMPPTNSGIFFSAGMSITLLGYNFLASSIPALFSMYIDPKLKVQLMPSI
GAISGIGKLVAPIVLAALYGTRLGLSIAVGFGMILVAVSIPPLIWLRKKRC"
gene 746943..748766
/locus_tag="YNR063W"
/db_xref="GeneID:855800"
mRNA 746943..748766
/locus_tag="YNR063W"
/product="hypothetical protein"
/transcript_id="NM_001183240.3"
/db_xref="GI:398365860"
/db_xref="GeneID:855800"
CDS 746943..748766
/locus_tag="YNR063W"
/note="Putative zinc-cluster hypothetical protein"
/codon_start=1
/product="hypothetical protein"
/protein_id="NP_014461.3"
/db_xref="GI:398365861"
/db_xref="SGD:S000005346"
/db_xref="GeneID:855800"
/translation="MDRSKDARKRSISLACTVCRKRKLKCDGNKPCGRCIRLNTPKEC
IYNIDKRKDKRKIKNGSKVFLFKNNTIDNGNNSILENKGLNEDLSSHIYEKEAPKFDS
DIDISRFGTNDAVIFNNDGWDTSLPIDFDFDEFNTETTDFDDFLKLLGDNSPSKEQKS
LSYSPTATGLSGVVKETESEDNAPTRSRLIDVLFENKLHSVPGISKWHLYELESQYPN
LECTEGNSDEKFLLSTVLCLGSLTIRKRELLNHSNIDNRPLLPENSISKLTTDAFKYY
NAAKTLVPDLLSHPTIDGFCGLVLMANFMTMMISLEHQLYLSINALQLAVALNLNNNT
KCKELLESNSDGIGVILLFWNIWCSSCMLATIHGKNPFITLEQITTPLPCEISPRNKT
NKLLIDFMQIRIKLATLQSKIFQRLYTSSTANEVPFVNLEREFEEVSLQITRLKGFPI
FEEHLFYRSRVLMLELSCLRAQASFLLYRPYLITGESLQAVTMAKSIIHEIWSQYTKQ
FPDNEKERHERLDWNFCYPLRTASLTLCISCIILLRYKQVVQFLKGTELFEYILALEI
LQDLVQVLPIEQNLIDIIKYPISPVQLSGDSFVEFWGRILY"
gene complement(749136..750008)
/locus_tag="YNR064C"
/db_xref="GeneID:855801"
mRNA complement(749136..750008)
/locus_tag="YNR064C"
/product="epoxide hydrolase"
/transcript_id="NM_001183241.1"
/db_xref="GI:296147826"
/db_xref="GeneID:855801"
CDS complement(749136..750008)
/locus_tag="YNR064C"
/EC_number="3.1.-.-"
/note="Epoxide hydrolase, member of the alpha/beta
hydrolase fold family; may have a role in detoxification
of epoxides"
/codon_start=1
/product="epoxide hydrolase"
/protein_id="NP_014462.1"
/db_xref="GI:6324392"
/db_xref="SGD:S000005347"
/db_xref="GeneID:855801"
/translation="MSNIIARFHKIQVQDGVKVWYREAGAAGNPTILLLHGFPTSSNM
FRNLIPLLAGQFHIIAPDLPGFGFTETPENYKFSFDSLCESIGYLLDTLSIEKFAMYI
FDYGSPVGFRLALKFPSRITGIVTQNGNAYEEGLDDRFWGPLKEYWKSYQSDPVFVKS
LIPYLEDPANVICQYHDGVPAIESVDPAAYTLDIALIQRTGQTDIQLRLFFDYQNNIK
LYPAFQKFLRDSKIPVLVAWGANDTIFSVAGAEAYRKDVDNLKVVYYDTGHFALETHV
VAIAEEIISMFAEN"
gene complement(750350..753700)
/locus_tag="YNR065C"
/db_xref="GeneID:855802"
mRNA complement(750350..753700)
/locus_tag="YNR065C"
/product="hypothetical protein"
/transcript_id="NM_001183242.1"
/db_xref="GI:296147827"
/db_xref="GeneID:855802"
CDS complement(750350..753700)
/locus_tag="YNR065C"
/note="hypothetical protein; protein-protein interactions
suggest a possible role in actin patch formation; YNR065C
is not an essential gene"
/codon_start=1
/product="hypothetical protein"
/protein_id="NP_014463.1"
/db_xref="GI:6324393"
/db_xref="SGD:S000005348"
/db_xref="GeneID:855802"
/translation="MLMTGSVGDGSEFDWEDQKTFISRDGGLTWRFVHNSSGLYATGD
LGNIIVYIPYDPEEDGDFQSEFYYSLDQGRTWNEYELTNAISSVHPYKLINPTPDGSG
SKFIFKGTFATTDSETNSITSLKGVEYIIDFSAAFDSRTCEEEDFEDWDLADGKCVNG
AKYKYRRRKQDAQCLVKKAFKDLSLDETPCNSCGESDYECSFEFVRDANGLCIPDYNL
IAFSNICDKSKDKSVLVEPLQLIKGDECKTPMKIEPVDIPCDEIPEEGSSDREIVTTE
NKFDFEIKFYQYFDTVADESLVMLNSIGDAYISHDGGQTIKRFDTNGEKIVEVVFNPY
FNSSAYLFGSKGNIFSTHDRGHSFMIAKLPEARQLGMPLDFSAKAQDTFIYYGGKNCE
SILSPECHAVAYLTKDGGETFTEMLDNAIHCEFAGTLFEYPSNEEMVMCQVKKKSSET
RSLVSSIDFFQGDNKIIFENIIGYLSTGGYIIVAVPHEDNELRAYVTIDGTEFAEAKF
PYGQDVSKQEAFTILGSEKGSIFLHLATNLESGHDFGNLLKSNSNGTSFVTLEHAVNR
NTFGYVDFEKVQGLEGIIITNIVSNREKVGENKEDEQLKTKITFNDGSDWNFLKPPKK
DSEGKKFPCDSVSLDKCSLHLHGYTERKDIRDTYSSGSALGMMFGVGNVGDKLLPYEE
CSTFLTTDGGETWTEVKKGPHQWEYGDHGGVLVLVPENAETDSISYSTDFGKTWKDYK
FCGDKVLVKDIITVPRDSALRFLLFGEAKNMGSGSFRTYTIDFRNIFERQCEFDITGK
KRADFKYSPLGSRTGCLFGHQTEFLRKTDEKCFIGNIPLSEFSRNVKNCSCTRQDFEC
DYNFYKASDGTCKLVKGLSSANGADICKKEPDLIEYYDSSGYRKIPLSTCKGGLKLDA
HLAPHPCPGKEKAFREKYSINTGAYALVFVTILLVIFFAAWFVYDRGIRRNGGFSRFE
EIRLGDDGLIENNRTDRVVNIIVRLGLCISLITKSAFQRTKAGVARFSSKLRARFGNR
KGPTYSSLLQGQFSDESDGLHEDANDLSSFTSQDSNFEIEQEDAYRPEQEHTSQIDQP
ATSNIPDALPARSAIHKPDSTAVRNEDE"
gene complement(753725..755035)
/locus_tag="YNR066C"
/db_xref="GeneID:855803"
mRNA complement(753725..755035)
/locus_tag="YNR066C"
/product="hypothetical protein"
/transcript_id="NM_001183243.3"
/db_xref="GI:398365872"
/db_xref="GeneID:855803"
CDS complement(753725..755035)
/locus_tag="YNR066C"
/note="Putative membrane-localized hypothetical protein"
/codon_start=1
/product="hypothetical protein"
/protein_id="NP_014464.3"
/db_xref="GI:398365873"
/db_xref="SGD:S000005349"
/db_xref="GeneID:855803"
/translation="MILLQVICTIWTCLFIPLLNAEEFVPKVTETLSEYSFSLESFDD
SNSLIRLDNQVVWISSDSGENWEAVKEIEGHILELIVDPLHGQDRAFVSIHLSPKFYV
TDDRGKSWRALTIPVSENCRLGTSCSIATHPTDKKYLIADCPCFINDNGYIQIQNETY
FTNDGESFYNIEPSLKKKEDDHITSSSCNFVKSSKDSDIEGNDASILCLFSNHGYDSD
RHLSAAYTQLALSTDGGKTFKKFDEFNDKIIYQYKILKSHIIVSTQDDRYNEMSPMDI
WISNDASTFQKARLPAQVRHVHMYGIYEDSIGRIIIPISTIFTDEKNDQPAPSEILIS
DSQGLKFLPVEWTINPHFGYIDIASPHFLEGTIIGSFHPSFDYSHNKGKYNKKIARYE
TKISVDNGLTWSNLKVVDEENADSFPCDITRPERCSLQNPFYSI"
gene complement(755746..759099)
/gene="DSE4"
/locus_tag="YNR067C"
/gene_synonym="ENG1"
/db_xref="GeneID:855804"
mRNA complement(755746..759099)
/gene="DSE4"
/locus_tag="YNR067C"
/gene_synonym="ENG1"
/product="Dse4p"
/transcript_id="NM_001183244.1"
/db_xref="GI:296147829"
/db_xref="GeneID:855804"
CDS complement(755746..759099)
/gene="DSE4"
/locus_tag="YNR067C"
/gene_synonym="ENG1"
/EC_number="3.2.1.6"
/note="Daughter cell-specific secreted protein with
similarity to glucanases, degrades cell wall from the
daughter side causing daughter to separate from mother"
/codon_start=1
/product="Dse4p"
/protein_id="NP_014465.1"
/db_xref="GI:6324395"
/db_xref="SGD:S000005350"
/db_xref="GeneID:855804"
/translation="MQLYLTLLFLLSFVECSYISFISNNADEILETDLIETLSYATLT
VGEPYVAQSVVVTRVSAASHSPLSVSPKNRVSASPINSQDSDSNTRTAVQLSLSLSNY
ASQVSQKISAQTNNDPVTVSNIYANDNSKSKSSVHNLSSVSGVASVMPSASTMRKVTT
LLSQTASTSTSTLFSSSLSISGTQLNGTLLTSVSKGTIDPLVTQMPSYSSQETKIIPS
SLTSNKTIYTISVRTNAATATGEDSFIASTPASSTLFYPSNSTQDLVQTLASTTASPA
YPSNRTQITLSPSVSLYSTTSPIYPSNITENGSSPSPSLSSTVSPVYPSSSTGNILLS
SLFSTVDSSSSPVSSTLDTIYVSSSMQATISSSSSSRQTKTSSSSLSTSTSSTATTTE
NSSTTTIVNLFNAVSTDEPPTVFDRSPNPMSLADGVSNDGPIQTNKFYTNLIVGSQES
PAFVYPYSLWKYTSSSYGFAVQHTTVDQYSYGGYDSSGNAEYLVNPLGIAHVVFSASN
FDSSMTMQVDEMTLSSTRVVLSESNDSSNYLEIPLVQGMGFATGIYHGSLNAKIGSSV
GFNTIVSESSSNLAQGILKYRITLLNGVTWLCYVIGPDDLTSTDFSLEVSSEYEIKAS
ASVDGLIIQLAVAPSETDYEVFYDQAAGMYVTNFKLQGVSDGSTATYEFSYTTQGESA
SGSTMIFALPHHESSFSDIMQDYYTGIQLASTTKGVMNGYLTTSLQFSTSLNRQISWL
PWSSQLGSNLLEYSKEQLQLLAEVANSELQVSISESISGLNTYYLGKVIDKYSYILLT
VSEIIQDEASTKSTLENIKSAFDILLQNEQTYPLIYDTKFNGLVSSGDWGSTSTQYDF
GNTYYNDHHFHYGYIIHAAAVIGYVDSKLNGTWAADNKDWVNSLVRDVANPSEKDEYF
AQSRMFDWFNGHSWAAGLYENGNGKNEESSSEDYNFAYAMKLWGATIGDQSMELRGDL
MISIMKDAMNDYFYYQNDNTVEPEEIIGNKVSGILFDNIIDYTTYFGTNTEYIHGIHM
LPITPVSSNIRSETFVEEEWQTKIEPIIESIESGWTGILKLNQALFDPVDSYAFFSDS
TFDSSTYLDNGMSRTWALAFSGGLANSIA"
gene complement(760067..760885)
/locus_tag="YNR068C"
/gene_synonym="BUL3"
/db_xref="GeneID:855805"
mRNA complement(760067..760885)
/locus_tag="YNR068C"
/gene_synonym="BUL3"
/product="hypothetical protein"
/transcript_id="NM_001183245.1"
/db_xref="GI:296147830"
/db_xref="GeneID:855805"
CDS complement(760067..760885)
/locus_tag="YNR068C"
/gene_synonym="BUL3"
/note="hypothetical protein; exhibits homology to
C-terminal end of Bul1p; expressed as a readthrough
product of BSC5, the readthrough locus being termed BUL3;
the BUL3 readthrough product is involved in
ubiquitin-mediated sorting of plasma membrane proteins and
interacts with WW domains of Rsp5p in vitro, but in a
functionally different way than the non-readthrough form"
/codon_start=1
/product="hypothetical protein"
/protein_id="NP_014466.1"
/db_xref="GI:6324396"
/db_xref="SGD:S000005351"
/db_xref="GeneID:855805"
/translation="MRNRQNQKNWTNLRGLLSVEEREKLENLRLELVCMQAANSIPHD
PPEISSLETELICLTTNTKDCKPVRFHSDLLLKKHKYNEIKKIFKEILENIEAYRDEF
TKNQTKINLLLADDARASLRNRSLDFSDLMPSSIIKDVQVLANMEANVVVMKNALKTK
LVGEKSVPVASSPISSIIPRTSRNKKTSPSNYHHSVLSHRKSNEWNQVSSTEYKRTLL
LNIKYNDDFKATIVPSFESCLCSRSYFLRVKLHFDKGVGSAEIDIPVQVKNSFI"
gene complement(761123..762592)
/gene="BSC5"
/locus_tag="YNR069C"
/gene_synonym="BUL3"
/db_xref="GeneID:855806"
mRNA complement(761123..762592)
/gene="BSC5"
/locus_tag="YNR069C"
/gene_synonym="BUL3"
/product="Bsc5p"
/transcript_id="NM_001183246.3"
/db_xref="GI:398365886"
/db_xref="GeneID:855806"
CDS complement(761123..762592)
/gene="BSC5"
/locus_tag="YNR069C"
/gene_synonym="BUL3"
/note="hypothetical protein; shows homology with
N-terminal end of Bul1p; ORF exhibits genomic organization
compatible with a translational readthrough-dependent mode
of expression; readthrough expression includes YNR068C and
the locus for this readthrough is termed BUL3; Bul3p is
involved in ubiquitin-mediated sorting of plasma membrane
proteins; readthrough and shortened forms of Bul3p
interact with Rsp5p differently in vitro"
/codon_start=1
/product="Bsc5p"
/protein_id="NP_014467.3"
/db_xref="GI:398365887"
/db_xref="SGD:S000005352"
/db_xref="GeneID:855806"
/translation="MQESKEPQNKFEGCQRISSSSSTLFGGTSFEEPRCGTSQGKEED
AFACNNGDHCSSITNVQEDDFVLPELLPSFEMYENLLSNIPQSSFDTYFPENPPFYEV
ASRNQSIPSEGESGNDMRILTGDIVGPDNHEVTVDGRRFASGPAESQIRNYDDTKGIP
VENIYALPRIKTPIATELYVTKTAPKFGQLPKHESMLREYTSGDIIHGYFTVENKSTK
PIKFDMFYLTLEGTTSSKTQSPFGIQKTTERILRMVDMAASWSYNHEDVNTGEDLCGF
FDSIDKTSFGLPNSRILNPGDKRKKFFTFKIPNQLLDVTCKHGHFSHSLLPPTLGFDR
PSSSHPELSTLKFSESLGYGRLSERGSSLWLNDSSSGSLINYSINAMIVGKDVASGRV
CLMSEKKYSIRIVPFGFQNNPISREKCLKDLEDFDIEIANRLGMIEKVFSKIERAIPI
HKEDIQEANRSDQLSPLRGKYEWNAVAGNTENGTLKKKH"
gene 765375..769376
/gene="PDR18"
/locus_tag="YNR070W"
/db_xref="GeneID:855807"
mRNA 765375..769376
/gene="PDR18"
/locus_tag="YNR070W"
/product="ATP-binding cassette multidrug transporter
PDR18"
/transcript_id="NM_001183247.4"
/db_xref="GI:398365892"
/db_xref="GeneID:855807"
CDS 765375..769376
/gene="PDR18"
/locus_tag="YNR070W"
/note="Putative transporter of the ATP-binding cassette
(ABC) family, implicated in pleiotropic drug resistance;
the authentic, non-tagged protein is detected in highly
purified mitochondria in high-throughput studies"
/codon_start=1
/product="ATP-binding cassette multidrug transporter
PDR18"
/protein_id="NP_014468.3"
/db_xref="GI:398365893"
/db_xref="SGD:S000005353"
/db_xref="GeneID:855807"
/translation="MECVSVEGLDSSFLEGQTFGDILCLPWTIIKGIRERKNRNKMKI
ILKNVSLLAKSGEMVLVLGRPGAGCTSFLKSAAGETSQFAGGVTTGHISYDGIPQKEM
MQHYKPDVIYNGEQDVHFPHLTVKQTLDFAISCKMPAKRVNNVTKEEYITANREFYAK
IFGLTHTFDTKVGNDFISGVSGGERKRVSIAEALAAKGSIYCWDNATRGLDSSTALEF
ARAIRTMTNLLGTTALVTVYQASENIYETFDKVTVLYAGRQIFCGKTTEAKDYFENMG
YLCPPRQSTAEYLTAITDPNGLHEIKPGFEYQVPHTADEFEKYWLDSPEYARLKGEIQ
KYKHEVNTEWTKKTYNESMAQEKSKGTRKKSYYTVSYWEQIRLCTIRGFLRIYGDKSY
TVINTCAAIAQAFITGSLFYQAPSSTLGAFSRSGVLFFSLLYYSLMGLANISFEHRPI
LQKHKVYSLYHPSAEALASTISSFPFRMIGLTFFIIILYFLAGLHRSAGAFFTMYLLL
TMCSEAITSLFQMVSSLCDTLSQANSIAGVVMLSIAMYSTYMIQLPSMHPWFKWISYI
LPIRYAFESMLNAEFHGRHMDCGGTLVPSGPGFENILPENQVCAFVGSRPGQSWVLGD
DYLRAQYQYEYKNTWRNFGIMWCFLIGYIVLRAVFTEYKSPVKSGGDALVVKKGTKNA
IQRSWSSKNDEENLNASIATQDMKEIASSNDDSTSADFEGLESTGVFIWKNVSFTIPH
SSGQRKLLDSVSGYCVPGTLTALIGESGAGKTTLLNTLAQRNVGTITGDMLVDGLPMD
ASFKRRTGYVQQQDLHVAELTVKESLQFSARMRRPQSIPDAEKMEYVEKIISILEMQE
FSEALVGEIGYGLNVEQRKKLSIGVELVGKPDLLLFLDEPTSGLDSQSAWAVVKMLKR
LALAGQSILCTIHQPSATLFEQFDRLLLLGKGGQTIYFGEIGKNSSSVIKYFEKNGAR
KCQQNENPAEYILEAIGAGATASVQQNWPDIWQKSHEYANINEKINDMIKDLSSTTLH
KTATRASKYATSYSYQFHHVLKRSSLTFWRNLNYIMAKMMLLMISGLFIGFTFFHVGV
NAIGLQNSLFACFMAIVISAPATNQIQERATVAKELYEVRESKSNMFHWSLLLITHYL
NELPYHLLFSTIFFVSSYFPLGVFTEASRSSVFYLNYAILFQLYYIGLALMILYMSPN
LQSANVIVGFILSFLLSFCGAVQPASLMPGFWTFMWKLSPYTYFLQNLVGLLMHDKPV
RCSKKELSLFNPPVGQTCGEFTKPFFEFGTGYIANPDATADCAYCQYKVGDEYLARIN
ASFSYLWRNFGFI"
gene complement(770440..771468)
/locus_tag="YNR071C"
/db_xref="GeneID:855808"
mRNA complement(770440..771468)
/locus_tag="YNR071C"
/product="aldose 1-epimerase superfamily protein"
/transcript_id="NM_001183248.1"
/db_xref="GI:296147833"
/db_xref="GeneID:855808"
CDS complement(770440..771468)
/locus_tag="YNR071C"
/EC_number="5.-.-.-"
/note="Putative aldose 1-epimerase"
/codon_start=1
/product="aldose 1-epimerase superfamily protein"
/protein_id="NP_014469.1"
/db_xref="GI:6324399"
/db_xref="SGD:S000005354"
/db_xref="GeneID:855808"
/translation="MSNSNGDNKYGVITIGDEKKFQATIAPLGATLVDLKVNGQSVVQ
GYSNVQDYLTDGNMMGATVGRYANRIAKGVFSLDDGPHKLTVNNCGNTNHSSISSLNL
KQYKASPVENPSKGVYVVEFKLLDDHTQPNPNEFPGDLEVTVKYTLNVAEMTLDMEYQ
AQLVRGDATPINMTNHSYFNLNKVKSEKSIRGTEVKVCSNKSLEVTEGALLPTGKIIE
RNIATFDSTKPTVLHEDTPVFDCTFIIDANKDLKTTDSVSVNKLVPVFKAYHPESHIK
FEVSTTEPTVHLYTGDNLCGKFVPRSGFAVQQGRYVDAINRDEWRGCVLLKRGEVYTS
KTQYKFDI"
gene 772657..774351
/gene="HXT17"
/locus_tag="YNR072W"
/db_xref="GeneID:855809"
mRNA 772657..774351
/gene="HXT17"
/locus_tag="YNR072W"
/product="Hxt17p"
/transcript_id="NM_001183249.1"
/db_xref="GI:296147834"
/db_xref="GeneID:855809"
CDS 772657..774351
/gene="HXT17"
/locus_tag="YNR072W"
/note="Hexose transporter, up-regulated in media
containing raffinose and galactose at pH 7.7 versus pH
4.7, repressed by high levels of glucose"
/codon_start=1
/product="Hxt17p"
/protein_id="NP_014470.1"
/db_xref="GI:6324400"
/db_xref="SGD:S000005355"
/db_xref="GeneID:855809"
/translation="MQSSTESDRDIQDGPDADIHVAPPVEKEWSDGFDDNEVINGDNV
EPPKRGLIGYLVIYLLCYPISFGGFLPGWDSGITAGFINMDNFKMNFGSYKHSTGEYY
LSNVRMGLLVAMFSIGCAIGGLIFARLADTLGRRLAIVIVVLVYMVGAIIQISSNHKW
YQYFVGKIIYGLGAGGCSVLCPMLLSEIAPTDLRGGLVSLYQLNMTFGIFLGYCSVYG
TRKYDNTAQWRVPLGLCFLWTLIIIIGMLLVPESPRYLIECERHEEARASIAKINKVS
PEDPWVLKQADEINAGVLAQRELGEASWKELFSVKTKVLQRLITGILVQTFLQLTGEN
YFFFYGTTIFKSVGLTDGFETSIVLGTVNFFSTIIAVMVVDKIGRRKCLLFGAAGMMA
CMVIFASIGVKCLYPHGQDGPSSKGAGNAMIVFTCFYIFCFATTWAPVAYIVVAESFP
SKVKSRAMSISTACNWLWQFLIGFFTPFITGSIHFYYGYVFVGCLVAMFLYVFFFLPE
TIGLSLEEIQLLYEEGIKPWKSASWVPPSRRGIPSEESKTEKKDWKKFLKFSKGSD"
gene complement(774792..776300)
/locus_tag="YNR073C"
/db_xref="GeneID:855810"
mRNA complement(774792..776300)
/locus_tag="YNR073C"
/product="putative mannitol dehydrogenase"
/transcript_id="NM_001183250.3"
/db_xref="GI:398365900"
/db_xref="GeneID:855810"
CDS complement(774792..776300)
/locus_tag="YNR073C"
/EC_number="1.1.-.-"
/note="Putative mannitol dehydrogenase; identical in amino
acid sequence to Dsf1p"
/codon_start=1
/product="putative mannitol dehydrogenase"
/protein_id="NP_014471.3"
/db_xref="GI:398365901"
/db_xref="SGD:S000005356"
/db_xref="GeneID:855810"
/translation="MTKSDETTATSLNAKTLKSFESTLPIPTYPREGVKQGIVHLGVG
AFHRSHLAVFMHRLMQEHHLKDWSICGVGLMKADALMRDAMKAQDCLYTLVERGIKDT
NAYIVGSITAYMYAPDDPRAVIEKMANPDTHIVSLTVTENGYYHSEATNSLMTDAPEI
INDLNHPEKPDTLYGYLYEALLLRYKRGLTPFTIMSCDNMPQNGVTVKTMLVAFAKLK
KDEKFAAWIEDKVTSPNSMVDRVTPRCTDKERKYVADTWGIKDQCPVVAEPFIQWVLE
DNFSDGRPPWELVGVQVVKDVDSYELMKLRLLNGGHSAMGYLGYLAGYTYIHEVVNDP
TINKYIRVLMREEVIPLLPKVPGVDFEEYTASVLERFSNPAIQDTVARICLMGSGKMP
KYVLPSIYEQLRKPDGKYKLLAVCVAGWFRYLTGVDMNGKPFEIEDPMAPTLKAAAVK
GGKDPHELLNIEVLFSPEIRDNKEFVAQLTHSLETVYDKGPIAAIKEILDQV"
gene complement(777602..778738)
/gene="AIF1"
/locus_tag="YNR074C"
/gene_synonym="CPD1"
/db_xref="GeneID:855811"
mRNA complement(777602..778738)
/gene="AIF1"
/locus_tag="YNR074C"
/gene_synonym="CPD1"
/product="Aif1p"
/transcript_id="NM_001183251.1"
/db_xref="GI:296147836"
/db_xref="GeneID:855811"
CDS complement(777602..778738)
/gene="AIF1"
/locus_tag="YNR074C"
/gene_synonym="CPD1"
/EC_number="1.-.-.-"
/note="Mitochondrial cell death effector that translocates
to the nucleus in response to apoptotic stimuli, homolog
of mammalian Apoptosis-Inducing Factor, putative
reductase"
/codon_start=1
/product="Aif1p"
/protein_id="NP_014472.1"
/db_xref="GI:6324402"
/db_xref="SGD:S000005357"
/db_xref="GeneID:855811"
/translation="MTINTKNIVVVGAGVFGVSVANHLYRELGGTYAIKLVTASNYVY
FLPSAVRLTVSKDYTKSILPLKNVLDSGIEVIKDTAASFDDKEVVLGSDRAIKFDILV
LATGSKWADPIGSTYTFGDNYKEYFEREASRISDADHILFLGGGFVNCELAGELLFKY
LEEIRSGKKRISIIHNSDKLLPDSGLYNDTLRKNVTDYLSKNGITLYLNTVGASLDTS
PKRIFLGEGSSKYIDADLIYRGVGISPNVPVNSISDLCDKKGFIQVEKNFRVKAVEAG
NVFAIGDVTNFRYHGLVKRDNWVDVLTRNVISSLQEGTEASLVDADCLETGHAPSGVS
LGPNAGFGQFPLPLLGTINIPSFLISRAKSKNLFSDKMEPLFKK"
gene 779916..781040
/gene="COS10"
/locus_tag="YNR075W"
/db_xref="GeneID:855812"
mRNA 779916..781040
/gene="COS10"
/locus_tag="YNR075W"
/product="Cos10p"
/transcript_id="NM_001183252.1"
/db_xref="GI:296147837"
/db_xref="GeneID:855812"
CDS 779916..781040
/gene="COS10"
/locus_tag="YNR075W"
/note="hypothetical protein, member of the DUP380
subfamily of conserved, often subtelomerically-encoded
proteins"
/codon_start=1
/product="Cos10p"
/protein_id="NP_014473.1"
/db_xref="GI:6324403"
/db_xref="SGD:S000005358"
/db_xref="GeneID:855812"
/translation="MGEEIRLLSSKGLETHSSFCLPEDIFRNRLTWLCSEIRNSGFWI
WSLSWLPLAVWWGMASTWFYPLLTSVVLILALIAILPVVQIQYSKYTLSNQLTQLSKE
IIKSAPGAYSADWDAVAIHFNSYLYENKAWKTAHFFFNGTDCQEAFRKTILEPAVLRR
QNEDPRFSSIEILVPYTEDAVQVYFTKVNAQWRLIHGKKECKLTMLENVKLPKETYRC
KLAWSCQRIRISFSPLDFLPDMSDFFICANLSPACLVSYWLIDIFFRMIDDFQNIRPK
SMKVDDKMQYLSDIINEQGASPEKWDTIARKTNTRLFEKRVWKNEEFFFDGTDCQAFF
ERNFSSLLFSKKSASPRSLNVELWKYIQEAQLSCNYEPLP"
gene complement(781511..781603)
/locus_tag="YNR075C-A"
/db_xref="GeneID:1466517"
mRNA complement(781511..781603)
/locus_tag="YNR075C-A"
/product="hypothetical protein"
/transcript_id="NM_001184621.3"
/db_xref="GI:398365924"
/db_xref="GeneID:1466517"
CDS complement(781511..781603)
/locus_tag="YNR075C-A"
/note="Identified by gene-trapping, microarray-based
expression analysis, and genome-wide homology searching"
/codon_start=1
/product="hypothetical protein"
/protein_id="NP_878159.3"
/db_xref="GI:398365925"
/db_xref="SGD:S000028706"
/db_xref="GeneID:1466517"
/translation="MPIIGVPRCLENPFCAPAKFPLSVKKKIRI"
gene 781918..782280
/gene="PAU6"
/locus_tag="YNR076W"
/db_xref="GeneID:855813"
mRNA 781918..782280
/gene="PAU6"
/locus_tag="YNR076W"
/product="Pau6p"
/transcript_id="NM_001183253.3"
/db_xref="GI:398365930"
/db_xref="GeneID:855813"
CDS 781918..782280
/gene="PAU6"
/locus_tag="YNR076W"
/note="Member of the seripauperin multigene family encoded
mainly in subtelomeric regions, active during alcoholic
fermentation, regulated by anaerobiosis, negatively
regulated by oxygen, repressed by heme; identical to
Pau18p"
/codon_start=1
/product="Pau6p"
/protein_id="NP_014474.3"
/db_xref="GI:398365931"
/db_xref="SGD:S000005359"
/db_xref="GeneID:855813"
/translation="MVKLTSIAAGVAAIAATASATTTLAQSDERVNLVELGVYVSDIR
AHLAQYYMFQAAHPTETYPVEVAEAVFNYGDFTTMLTGIAPDQVTRMITGVPWYSTRL
KPAISKALSKDGIYTIAN"
telomere 783278..784333
/note="TEL14R; Telomeric region on the right arm of
Chromosome XIV, composed of an X element core sequence, X
element combinatorial repeats, and a terminal stretch of
telomeric repeats"
/db_xref="SGD:S000028993"
repeat_region 783278..783740
/note="TEL14R-XC; Telomeric X element Core sequence on the
right arm of Chromosome XIV; contains an ARS consensus
sequence, an Abf1p binding site consensus sequence, and
ORF YNR077C"
/rpt_family="X element Core sequence"
/db_xref="SGD:S000028995"
gene complement(783287..783541)
/locus_tag="YNR077C"
/db_xref="GeneID:855814"
mRNA complement(783287..783541)
/locus_tag="YNR077C"
/product="hypothetical protein"
/transcript_id="NM_001267862.1"
/db_xref="GI:392861357"
/db_xref="GeneID:855814"
CDS complement(783287..783541)
/locus_tag="YNR077C"
/note="hypothetical protein, abundance changes with carbon
source"
/codon_start=1
/product="hypothetical protein"
/protein_id="NP_001254791.1"
/db_xref="GI:392861358"
/db_xref="SGD:S000005360"
/db_xref="GeneID:855814"
/translation="MHGTCLSGLYPEPFTHNSHDYPHFNIYISFGGPKYCITALNTYV
IPLLHHILTTQFIHTYFNIPTKSPPKSPKHKNYLSFNFTK"
repeat_region 783741..784037
/note="TEL14R-XR; Telomeric X element combinatorial Repeat
region on the right arm of Chromosome XIV; contains
repeats of the D, C, B and A types, as well as Tbf1p
binding sites; formerly called SubTelomeric Repeats"
/rpt_family="X element Combinatorial Repeats"
/db_xref="SGD:S000028996"
repeat_region 784038..784333
/note="TEL14R-TR; Terminal stretch of telomeric repeats on
the right arm of Chromosome XIV"
/rpt_family="Telomeric Repeat"
/db_xref="SGD:S000028994"
ORIGIN
1 ccggctttct gaccgaaatt aaaaaaaaaa aatgaaaatg aaaccctgtt ctttagccct
61 acagcacttc tacatagccc taaatagccc taaatagccc tcatgtacgt ctcctccaag
121 ccctgttgtc tcttacccgg atgttcaacc aaaagctact tactaccttt attttatgtt
181 tactttttat agattgtctt tttatcctac tctttcccac ttgtctctcg ctactgccgt
241 gcaacaaaca ctaaatcaaa acagtgaaat actactacat caaaacgcat attccctaga
301 aaaaaaaatt tcttacaata tactatacta cacaatacat aatcactgac tttcgtaaca
361 acaatttcct tcactctcca acttctctgc tcgaatctct acataataat atatcaaatc
421 taccgtctgg aacatcatcg ctatccagct ctttgtgaac cgctaccatc agcatgtaca
481 gcggtaccct cgtgttatct gcagcgagaa cttcaacgtt tgccaaatca agccaatgtg
541 gtaacaacca cacctccgaa atctgctcca aaagatattc cagtttctgc cgaaatgttt
601 tattgcagaa cagccctatc agcatcgaca ggaatgccgt ccaatgcggc actttagatg
661 gggtaactcc cagcgcaagc tgatctcgca agtgcattcc tagacttaat tcatatctgc
721 tcctcaactg tcgatgatgc ctgctaaact gcagcttgac gtactgcgga ccctgcagtc
781 cagcgctcgt catggaacgc aaacgctgaa aaactccaac tttctcgagc gcttccacaa
841 agaccgtatc gtcttttgcc tcccattctt cccggcactt tttttcgtcc cagttcaaaa
901 agtactgcag cacctctgtc ttcgattcac gcaagttgct ccatacttta taatacaact
961 ctttgatctg ccttccagac atgcggaaaa cttggctccc ttgcttgcct cttgtcgaat
1021 ccaatacact aattgtttct cttcttctag taatggccag gtaccaagca taatttctct
1081 gtatctgaga gtagatctct ccccttttta cgctaaaaaa tttcaaatac cctacagggt
1141 ccccatgata tggctcgatg tcttccaagt attctttgta ttcctcgtca tttcgcagca
1201 ttctctccac agctagtgct tcccaagcca tcctccgata cgatactttc tggccagccc
1261 aacagacaca gagctcgaac atcttttgac agcccttgca taatccgtat tgtgtgaata
1321 ctccctctgg gcagaagtat acgtcaatac catagaggaa aagatgttta atttcgtcag
1381 accgaaatcc aagaaactgt aagacattca tattctcgga agtattggga aattgtgctt
1441 tcagtttctt tctctctagc aaaaccattt gactcccttt ccgcttatac gactctttgt
1501 taatgtcggt gactggatgg aatctattat cctcagcatt gccatcttta ttggcgtcct
1561 ccttggcact agcgttggta ctttcagtgg tagtggcatt agtgctggag ttggtgctag
1621 cagtggtagt ggcattagtg ctggagttgg tgctagcagt ggtagtagca ctagtgttgg
1681 agtcggtact ttcggtggta gtagcactag tgttggagtc ggtactttcg gtggtagtag
1741 cactagtgtt ggagttggta ctttcagtgg tagtcgcact agtcctgacg ttgatgctgg
1801 cagtggtagt agcactagtc ctgacgttgg tgctggcagt ggtagtagca ttagtgctgg
1861 agttggtact ttcagtggta gtcgcactag tcctgacgtt gatgctggca gtggtagtag
1921 cactagtcct gacgttggtg ctggcagtgg tagtagcatt agtgctggag ttggtagtcg
1981 cattggtact ggcattagca ctaccatgaa tgcacgtgtc gctgtcctca tcactgctgc
2041 aatactttct gcacctgtca ctgctattgc tctcctggaa gctagacggt aacgcaacga
2101 tcgacatgga agctgtcgcc tgtttttcag ccaatctgtc cattctttct atcagttcca
2161 ctgtgtcagc agacaggtct gtcctggagc cacagcatcc aacatgctgg cccttttttc
2221 ctttctttga ttcaagtcca tagaactcgc gtacctgttc ggttatacag ccttccttaa
2281 tcggtggtaa ttcaccctta cgattccttg ccgcccaact gttttttcta gataatagat
2341 aacagaggcc cccatctctt agtctcccta cgccttgaat gagctcaata atattaagtc
2401 tattatcaag catgatcacc atcatcaatt gcttaatgtc aattccttca gtcactaatt
2461 tcgttccgat gagaactcgc atgctaccgt cagtgacaaa ctcctttgtg cgagacacct
2521 tttctgcagc acccagcttc ccgtgtatcc ataccaccct aaaatacttt ctccaagagc
2581 aggccaattc ttccacttcg ttggttgtgc ttgcaactac aatggccttc gactctggtt
2641 caatttcaaa gagggctaaa agaagcttca gtgcttcttc gggctgtgat tccactttct
2701 tccaaatttt atgaacatgc cctaaaggca cctcggattt ctccttgatt agattaaaca
2761 tccgtgttgg atagctggat agacctctgc tgagatcttc cgaccgtttg agctcgttga
2821 tgtccatcga cttcttggcc agtcccgtaa gcccaatacg ctgcaacgca gcatcagcta
2881 cagcctcagg tgctgtgccg ctcaaaaaga ttgctttctc aaaagcgtca aaatcaaggt
2941 tagttatgcc cccaaattgc gactgccggt agacctccgt ttcaaagttg tgaaactcat
3001 ctacaatgag gtaacccaat tttacgttgt tggtcctaaa ggtgcactca acaatattct
3061 cccacgcagc tatcctgtct gtgaaattag tgctagcaag atcatcgtag atccccacgt
3121 ataaatcagt aacgccatcg caaccttctt caataaagtt tcttacaggg gccacattca
3181 agcaaccgca tcggctcaac ctgatcatgc aattagcaag caacactgtg tacggtacaa
3241 acagaaacga cacatatttc acgtcgccct tagacgccag tgctatcaag gggagatgaa
3301 ataactccgt cttaccatag cccggtgggg cctgtactgc cacagagggt gtgtctgcca
3361 tgtatatttc atgacataag cgcaactgat gcaagtccct gaattcaaag gagctgccaa
3421 agagtttctg gcctgcgacg aggatatcgt ttgtactctt gggctctcgg ggcctttttc
3481 gcgttactct tgaaattttt tgatgatgat ctgaactcgc cgcctcacct gccactacgt
3541 cttccgcatt ccgagtacta gagaatgaac aatggtagtc gctttcaagg cctaaccatt
3601 gaatccagcg ctcggaagct cgttcctgca ataaagtggc ggtcgtccca ctgacactag
3661 ttaacgaaaa ggaatccaca ccgtaaatat ttcgccctgt ttgaacggaa tgattggcca
3721 tgagttcact cgtcgccgac tcgtacaaat ctgtttcaaa tctgctacct acgcagtgcc
3781 gtcctagggc aatcaacccc tgacgcatct cccgaaaatt cagcttctga ggtgcattct
3841 tcggaagttc cctcatgtac tgccgaaaag ttgcgtattc aaccagacag cccttcgcgg
3901 tattcagaaa catgtaggaa tacaaaacta tcctcgaaat gtctcgattt gttacttgat
3961 ctggatcctc aaatcccacc acatccatcc aaggatcatg attaaaagcg tcataactgt
4021 taccaagcgc acatatttgc atttgcctta gcacagtgac aaaataaaac acgtaatctg
4081 aagtgagtcc gtcaagcgtc ttaagtcgag gctccgatga accgttcttg ttgtaatcag
4141 tgtacagttg gatgcgtctt gttgtatcat cgacgtatac gttgcgctga ggaccggcaa
4201 aagcgagtag ctgaagctct ggataacggt aagggtatcc tacggcaaaa tggatcatcc
4261 acataagtgg caccgtaagc tcgtcaattg caacagtgac tttattttta agagccgcgg
4321 tcattttgtt agtatctctt ctcaacttgg gcagcacaat ttcacgatat ttaacaggta
4381 tcatttgaag gaaagaatcg ttctccagat actcgtcaat tcctcgcttt ggctctctga
4441 acaaaacttc tcgattacgc aaaatgaggc tggcaatatc aaccactgta ggcatataaa
4501 agcagtcgtt caattcttcc caaaggttat caaactgagc cttgcatgca aagtaaaagc
4561 cgcggacata ctcgcgatta aacagttttc cacatactga tacaccatca gaagaaggta
4621 ccaaagttat tctataagag tccttcagcg cggtttcctg cgctacttcg tggtacagaa
4681 ttttgatcca tttccacatc gcaacgccgt tgttgtcatc aaatatatct aaatcccttg
4741 cggtacaagc acaagacgac accaataaag ctttcacggc atctagtgtt tttctgagtc
4801 ttcgtggagt gttaggactg cgcaacttac atactttcaa gccatgctcg tccacagagg
4861 gaataatggg ttcttcattc gtaatggatc gatcctcttc gtcaccagcg ccaccacggg
4921 gacccgcccc gaaattgagc gcacatgctc gcaagataat atgcaaaata tcacccaatc
4981 ggtccttttt gttcatcata tcgttacata tctgtgaaaa gtactttatc tcagtgggtt
5041 tacgtgggca tagatcacgc ttcagccgct ctgtgtcgac tttcttttcg ccaggtaaac
5101 ttgcttggta tgcagaaaaa atcgatagct catctacgtg tagtaacaaa aacatgtagg
5161 gtgccaaatt gtatccatat ttccttatgg tgcttttctg aagacccctt acaataggtg
5221 tgccagaaac aaagtcagtg aaagtacgca tcgtagagct gtcgttcggc ctggcactcg
5281 ctatttcgta acaacgttcc aggacacgga aactcaactc attatagtat cctctgttga
5341 ggtaaaaaag agaaagggta tcgtaatcct ttctattgaa tttcaaagta tgcacttgaa
5401 acaacgtgta gaccatcaag ttgattttct tgggaataag atactttgaa gggattggtc
5461 cgccctggaa atctggttcg tcttcaacaa acgtcaggaa cttttgtaca tttttcccga
5521 ccatgacgga aacgacaatt ttttcaaaag accttttcct atccattgca ccagttctga
5581 attttaccac tttgattaga ccagactttt cgtcttcgta gaatgaccgc acttccgtgg
5641 ggatcgattc aaataaagtt attgagggac aatgtaccaa gtcgtttttg ttatttagag
5701 ccgactcaaa ctcgtcaaag tttgcttttt caaacttacg cctatcggaa actttcattt
5761 tatttttgta agtttcgaaa ttaacaatag tatgttgatt gttatgcttt ttgacaagaa
5821 atccatcaat ataaacaaaa gattgtccag tttccgtctt atcatcatct aagaatgtaa
5881 taattaagct attgagaaga tgcagaatct gcgctatgca ggtgcaaatc tctagcagca
5941 gcaaagtaaa ttcagttagt aagaaatctc actaagataa gcgactgtct gtccccttca
6001 agcacaacat agaaagcaga aggatgtctc attcatcgct tgatttccgg cctgcaaaaa
6061 taaagtagtc ggtacgtacg ttcgttttca atttccatgg tgcacagtat cttaactatc
6121 tgcttagtcg aggagaacca ggattctgtt cgttgctcag ccgcttcgtg gatattctct
6181 tggatacttt aaatatggac ctacgcttag cctgcgctta gcctacaact tcttccgctc
6241 tcgaaaagac caatataata gaaagttata aattacattt ccttattagg tatacgacct
6301 cgcgcttcga agtagaggag ccctttttgg cgtacctaca tatggcgcgt cagacagaca
6361 aacttccccc aaaaatgtat taccccgccg aataagaaaa cagacccatt cacccacgac
6421 gtatcaagtt acttccttgg tgcaatgtcc cactataaaa aaattccttg acgctagatc
6481 gttggactaa aatctgcgtc acaatcgcct aaacaggaaa tattgcctat tttcgtacaa
6541 ggttacttcc tagatgctat atgtccctac ggccttgtct aacaccatcc agcatgcaat
6601 acagtgacat atatataccc acacccacac ccacacacca cacccacaca cccacaccac
6661 acccacaccc acacacccac acccacaccc atcacaaccc taaccctacc ctattctaac
6721 cctgatgaac gtgtctctca acttaccctc cattacccta cctccccact cgttaccctg
6781 ccccactcaa ccataccact cccaaccacc atccatcact ctacttacta ctaccatcca
6841 ccgcccatca taaccgttac cctccaatta cccaaatcca actctactac cattacccta
6901 ccatcgacca tctgctactc actatactgt tgttctaccc tccatattga aacgttaaca
6961 aataatcgta aataatacac atatacttac cctaccactc taatcccact accacatgcc
7021 atactcacct tcacttgtat tctgatcggt catacgtaca cggatgctac agtatatacc
7081 atctcaactt accctgccat aacattccac tccactccat ggcccatctc tcactaaatc
7141 agtaccaaat gcacccacat cattatgcac ggcacttgcc tcagcggtct ataccctgtg
7201 ccatttaccc ataactccca cgattatcca cattttaata tctatatctc attcggcggc
7261 cccaaatatt gtataactgc tcttaataca tacgttacac cacttttaca ccgtatacta
7321 accactcaat ttatatacac ttatgccaat attacaaaaa aatcaccact aaaatcacct
7381 aaacataaaa atattctatt cttcaaccat aatacataaa cacactcaat tgcgtatcaa
7441 taccaccatg acgtcattaa cttaaatgtt ccttaatacg tcataccact atgctctatt
7501 ccatatattg taatataact gtactctata gtcatacaga cgcttttact tcaccccatc
7561 ttctcatact attgtcatag aatctcacac tgacgcatga ttaaaacgaa taatttttac
7621 tgtaagggct gccatccgcg ctctatcctt ttgtttgcaa tatttatata cagaatctca
7681 aaacaagcgg gagaagtgct aattacccag aggtcatgca taatctgagt accaccgtac
7741 ctctaggttt tgctttgatc cgttttacag tgacaccgaa cataagggga agctattgac
7801 atggtatcga aaggttgtcc acattgggaa gtaacttggt tctatgaatc ttcatgtcag
7861 atacgtagga cagactcttc ctgtgtaaat atttgtgaca gctacgtcta ttttctacta
7921 gatgtttaca cagttttgtc acaggaaatc tacgcttaaa atatgtattt cattcaagcg
7981 gtaaccgctg tacgagcagt gacattgctg gtcgcacctt aaatgtaaac caacgttacg
8041 gcacaccgtg atgtacccgc attaaagttt tgtaaattcg ttattacgat tatcgagttg
8101 gctagataga aaaccggaaa tgaaatggat gcccttttcg aatagctgag tttctttgcc
8161 taaaatagcc caatattgtt tccctttttc tatcacgagg ttactgagcc attgcatgaa
8221 cgcgcgcgcc tcggcggctt tttttttctg ctgtgctgta taaaagcgaa aagccagaag
8281 ttactatctc gaataaaaaa cccctcgaac tgccatctca ctaccgaaaa tgaaagagaa
8341 tgaacttaaa aatgagaaga gtgtagatgt attatccttc aaacagctcg aatcccaaaa
8401 gattgttcta cctcaagatc ttttcagaag cagctttacc tggttttgtt atgaaattta
8461 caagtcctta gcgtttcgca tctggatgct attatggcta ccacttagcg tctggtggaa
8521 actttccaac aattgtattt acccacttat agtttcactt ctggtcctgt ttctgggacc
8581 aatatttgtc cttgttattt gtggactttc tcgtaagcgt tccttatcga aacaactcat
8641 tcagttttgc aaagaggtta ctgaaaacac accaagttct gatcctcatg attgggaagt
8701 tgttgcagca aatctaaatt cgtacttata tgaaaataag gcttggaata ctaagtactt
8761 tttcttcaat gccatggtct gtcaagaagc gttcagaaca acccttctcg aaccattttc
8821 tttgaaaaaa gacgaagctg ccaaggttaa gtcatttaag gattccgtcc cttacattga
8881 agaagcattg ggagtttatt ttagagaagt tgaaaaacaa tggaagttgt ttaattctga
8941 gaaatcatgg agccctgttg gcctggaaga tgctaaactt cccaaagaag cttaccgatt
9001 taagcttact tggtttttaa agaggatttc caatattttt atgttgatac cattccttaa
9061 ttttttgtgc tgcatatatg tgtcacgggg aatgtgcctt ctattacgca ccttttatct
9121 cgggtggatt cttttcatgt tggtacaagg tttccaaaac atgaggatga tcgttttatc
9181 cgtgaaaatg gaacacaaga tgcagttctt gtcgactatt ataaatgagc aagaaagtgg
9241 tgcgaatgga tgggacgaaa ttgcaaaaaa aatgaatagg tacttgtttg agaaaaaagt
9301 ctggaagaat gaagagtttt tctttgacgg gattgactgt gaatggtttt ttagccactt
9361 cttctaccgc gttctctctg caaagaaatc tatgcgggct ctatcattga atgtggaact
9421 atggccatat attaaagaag cgcaattatc ctgcagtgag gagtccttag cgtaaagata
9481 aatacaactt tttcaattta tatattttgt agtttgtcag ctgcgaataa ccaaaacgag
9541 actacttttt accattacaa ccattttctt tttccctatt tctcactggt tgacagaaat
9601 cagtgtgcta tcatcctacc atatgcgcta aacttattgt ctttctcctc ctagagatgc
9661 tgtattccat gcatattctg aacgatgggt tggtgttttt atcaagcaag gttaatcaca
9721 tggcgtggct tgctccacac atcagtagaa aacgcatacc gcagcggaat ccttaaataa
9781 taagtgattt tactgttcat caactacaat cggactcttt cacaattacc cttcttgttt
9841 tccacattta ctgttaaatg aagggatgta cagaaggctt aggaaaacct gtgctgaata
9901 ctggatggac actgcattcc cacagtgaaa cttttataga tacactgtca gttattttcg
9961 aactttcatc aagttgctga gttttagtat ccctttgcct tagctatatg tttgaatgag
10021 caaaatattt gcaatgtctc tagctttctt gaaatattgg tttatattga gggcttggta
10081 agatttcaaa tttcactttg aaatactcag gagaaaaatc atgctctttt gataatttgg
10141 tgactaaaca tacataaaac agtttaattt tgggtggtaa tggctgtgtg actagctata
10201 gaaagaaaaa aattaaaaaa aaaaaaaaaa atcaagtagt tcctgcactg cgacgtccat
10261 tatagcatta tgaattggtc cctgatttac gcatgcgata aactattttt agcgcagccg
10321 catattatcc gagaataact tccgacataa gaaaattcgc agaaaataga taaaaaactg
10381 ctcttggcat tcttcacttc ctctattaca cactgtgtca taccacaatc atctcacagt
10441 atgtatttgt atgtttatac atgctataac gtaaaacaat gtagaatata tatctaaata
10501 cctcacggtt ttagtttagt gcagcccaca tactactttt ttccttttgt ttttttttat
10561 atttcaaagg ttaaactcgc ttagactatg tctataatat aaaaaaaaaa atagctctat
10621 tccgtttctt ttattctatt tgatatttcc atcacacttt catcttaatc acggatgtat
10681 actgataata gggttgactg cgcctgtacg gattacagtg ccctcttcaa ttggaaaatc
10741 caagctttca agatgcgtaa ctgttattca aaggatcctc taagataaaa cacagatcgg
10801 cagatccgag agttggcttc tgtgccttgg gctcaaattc ctttcccacc tcattcaaat
10861 tgatttttct gactccaaaa aaagacaaag ccctgcgata gttcccgaat gttgtaacat
10921 caaagccaag cactccttta tagaagtcgc atgaacgttg aatactagca gctggtgaaa
10981 ctacagggtc taaactaact agtatccata tcgttttgag agcattgaaa gtatacggag
11041 tacaagctgg gttagaagga atttttatct taacagcaat gaaaatcaac tttctagact
11101 gaatccctca agaaaattgc aaaagactaa ccgatactgg tttaaaagag aaagatgtca
11161 aatatgcgga gttataccat caaacaactt tggacggccc cgaaacaaat gtccgcaaaa
11221 aagatcttat taaagtgcat ggacactatc atttctataa tacaaaatac tccaccgcac
11281 aatagtttgt cgggaagtca tcaatcaatc ttgtacgagc tttacaaata actttttagg
11341 atcggtcccc tcataaaatt atatataaat gggttagttt ccttcttctt ctgttaacat
11401 gaagttgctt cgtactgttt tttgccttgc tcctcttcaa aagaatcaat catgtcacag
11461 tacggatttg taagagttcc tagagaggta gaaaaggcca ttccagtggt gaatgcacct
11521 agaccacggg ccgttgttcc gcctccaaac agtgaaactg ctaggcttgt tcgggaatat
11581 gccgctaaag aattgactgc ccccgttcta aaccactctt tgcgtgtttt tcaatatagt
11641 gtagctatca taagagacca atttccagca tgggacttgg atcaggaagt tttgtacgtc
11701 acctgcttac ttcatgatat tgcaacaaca gataagaata tgagagccac gaagatgtca
11761 tttgagtatt atggtggcat actttcaagg gagcttgtat ttaatgcgac aggtggaaat
11821 caggactacg cagatgcagt aactgaggcc atcattcgtc accaggattt gactgggact
11881 ggctacatta ccaccttggg gctcattctg cagattgcta ctacgcttga caatgtcgga
11941 tccaataccg atctgattca tatcgataca gttagtgcca ttaacgagca atttccaaga
12001 ctgcactggt tatcatgttt tgctacggtg gtggacactg aaaactcgag aaaaccgtgg
12061 ggccacacca gttctttggg tgatgatttt tcaaagaaag tcatatgcaa tacatttggg
12121 tataactaaa taggtaagtt tcaatgaggc gagttcagaa tgaacagtga tgatctcctt
12181 tctccataac tatactatac gtccctttta tttactgtag tttttaagaa caaattctct
12241 gatgaaccag tcgtgaaacc gtatatcgtt ttctgccaat tccggatgaa atgatgtcgc
12301 aagaatattg tttttttgct tagcggcaac aattagttct tgaccaccat tatccttccc
12361 atctaatttg tacaggacct gcacatgttc aggatccagc acctcttcta ttactggggc
12421 tcttataaaa gtagcaggaa aatcattgca gtgaggaata aagtttgaaa agtcgcaaat
12481 ccgggtagaa gactgagctt gtctcccaaa tgcatttctt tttactttaa cctttagtaa
12541 attcagcgtc ttgaccagtt tttcttcgtt agataattgt tgtgaaatat aaatcatacc
12601 tgcacaagta ccccaggtta ccttgcttgg gttgtgtacg aatgcgtaga gatcgtcgta
12661 aaatcctgtt ctttctgcaa taagggacat tgcagtcgac tctcccccag gtatgatcaa
12721 tgcatcacat tgagctagtt gatttttatc cttcactgtc atcacagata gttttttttc
12781 atagaaatcc ctgttttcga cgatgcattt ttctacgtgt cgcacatgtt caatgaacgc
12841 accctgtaat gccaagactc cgataacgac ggtcattttt gagatattac tcttgtcttg
12901 gccccagcaa ccggggtcat ggtaagtgtg cttgctactc aaacagaaaa aaatgggctt
12961 ttatcaatga ataacttttt ttttttgtag ctgaatgatg aaagatggct caactattct
13021 tacagtttcc aataaagtga cgcgccgccc aatggcataa cagtagtagg cacattatat
13081 cgtttgaatg gcaaaatgtt gtggcaagga aagatcagaa ttatttgttc atgtggaatg
13141 aatttcacac acacacacac acatatataa aactagtatg tttctccacc atagtcacat
13201 tattattcga cccttctagg aaaggaacta taatagaaaa ataagtatat cgtaaaaaag
13261 acaaaaatgt cagaattcaa ggttaaaact gggcttgccc aaatgttaaa gggcggtgtg
13321 attatggacg tcgtcacacc tgaacaggct attatcgcag aaagagcggg cgcttgtgct
13381 gtaatggcat tggaacgcat tccagctgac atgcgcaagt ctggccaagt atgccgtatg
13441 tcagatcctc gcatgatcaa agaaattatg gaagctgttt caattccggt gatggcaaag
13501 gtccgtattg gacacttcgt ggaggcacag atcctggaag agctgcaagt agactacatt
13561 gacgaaagcg aggttttgac tccagctgat tggacacatc acattgagaa gcataacttc
13621 aaggtgccat ttgtttgcgg tgccaaggat ctaggtgagg ctttgagaag aataaacgaa
13681 ggtgctgcaa tgatccgtac caaaggtgaa gcaggtaccg gtgacgtttc cgaggccgtc
13741 aagcacatca ccaagattaa ggcggagatc cagcagtata aagagaattt gaagaccgaa
13801 tccgattttg cagctaaggc cacagaatta cgcgtccctg tcgacttgct gaagacaaca
13861 ctatcagagg gaaagctacc tgtagtcaat tttgctgctg gtggagttgc tactccagca
13921 gacgctgctc tattgatgca attgggttgt gaaggtgttt tcgtcggttc aggtatattc
13981 aaatcgtcag atcctgagaa gttagcatgt gctattgttg aagccacgac tcactacgat
14041 aatccagcaa aactgttgca aatttccagc gatttgggtg acttgatggg tggtatttcc
14101 atccaatcaa ttaatgaagc aggaggcaaa aacggtgcaa gactttctga aatcggatgg
14161 tagaactagc gatgctcaca caacgctaat ttgtttcctt cgaaggggca gtcggctatt
14221 gtagtttcta tatattatgt agcacaacat ggaaaccata ttcagccagt ttgtatatat
14281 gagaattaaa cgttaaaact ttttcatcct atcagtctta cacattggcc ttgctaaagg
14341 gcacaatcgt tcacgtatat acatatgtat gtttacgtat atatatatgt gtttacaaat
14401 atgcatgtat attcttttcg aggaagatta ttatatgcta ttaggcgatg agtcggctta
14461 attttttagg gggacgagat tggcgcgtta gtgcataaag acagcaaatc acctggaggt
14521 gacaacatta atgcatttat cggtttttgg ctatgatgca atgagtacag ttccaattga
14581 acggctcatg aactatgaaa tatacgaatt attcaactag cagaaggctt gaaatattac
14641 ttattcagat tatgaaaatg gtgctgttat agcaaaataa gcaacatcaa tctcttgcga
14701 cgacagcaaa caaaacatat aaaaacctcg tattatcatc ttcatgaaca atattcttgt
14761 ccattctttc gttcttttac cttttcaatt ttataaaaat accacaacaa caataaacac
14821 acttccaagc tatgtctaca gacaagatca catttttgtt gaactggcaa ccaaccccat
14881 accatattcc aattttcttg gctcaaacca aaggttactt caaggagcaa ggtctagaca
14941 tggccatcct agaaccaacc aatccttccg atgtcactga gttaattgga tctggtaagg
15001 tcgacatggg tttgaaagcc atgattcaca ccttggctgc caaggcccgt ggtttcccag
15061 tgacctctgt tgcctctttg ttggacgaac catttaccgg tgtcttgtac ttaaagggca
15121 gtggtatcac tgaagacttc cagtccctaa agggtaagaa gatcggttac gttggtgaat
15181 tcggtaagat ccaaatcgat gaattgacca agcactacgg tatgaagcca gaagactaca
15241 ccgcagtcag atgtggtatg aatgtcgcca agtacatcat cgaaggtaag attgatgctg
15301 gtattggtat cgaatgtatg caacaagtcg aattggaaga gtacttggct aagcaaggca
15361 gaccagcttc tgatgctaag atgttgagaa ttgacaagtt ggcttgcttg ggttgctgtt
15421 gcttctgtac cgttctttac atctgcaacg atgaattttt gaagaagaac cctgaaaagg
15481 tcagaaagtt cttgaaagcc atcaagaagg caaccgacta cgttctagcc gaccctgtga
15541 aggcttggaa agaatacatc gacttcaagc ctcgattgaa caacgatcta tcttacaagc
15601 aataccaaag atgttacgct tacttctctt catctttgta caatgttcac cgtgactgga
15661 agaaggttac cggttacggt aagagattag ccatcttgcc accagactat gtctcgaact
15721 acactaatga atacttgtcc tggccagaac cagaagaggt ttctgatcct ttggaagctc
15781 aaagattgat ggctattcat caagaaaaat gcagacagga aggtactttc aagagattgg
15841 ctcttccagc ttaaacgtgc ttcgtcactc gttcagccca gccttcctct acgacttgtt
15901 tatgatttca cattagctgt tgtttcctac tcgatatata gacatacata tttacgtatc
15961 agagcatgta tacaagcttt aaatgaactt cgtttatctt aacactttat ttccttgcaa
16021 aatttgcaca cactcggtgg ataaggcaac tgcgtataat ttgtagcttc ttttcaaaat
16081 atagtagatg gatattaaca taaaataatc actttaacta attgtcaaaa gctatcctgg
16141 cagacatcga tgtgaggggt gaaagcttct tggttaccgc tgggtcatct cctattaaac
16201 ttttgggaaa gccaacatca aaaggaacaa tactttccag gtattctatt tgttccggtg
16261 ttaatttaat actcaaagcc tcaatgttct gcttgagatg ttcaattttc cttcctccaa
16321 tcaatgggaa aacatttttc gctttagagc gaacataggc aatagcgata gcagtaacag
16381 actctgttcc atgttcctca gcaattttag tcaatgcttc gctgatttta acctccaatt
16441 ctgtttgttc ggggccaccc acaaaagtac gcagaccctc tccattcttc ttccgttctt
16501 ccattgcttt tttactctga aatcttccac ctcccatgac atcccatggg gctagagcca
16561 taccaaaatg cctagccatt ggaataatat cacgctcaaa gtccctgttc aatacattcc
16621 atttaccttg atagacgcta aaaggagttt taccatgaga tgtagcgtag taatttgccg
16681 cagaaacaac ccaagcaggt gtatcagata ctcctaaata taggaccttg ccctgctgaa
16741 ctaaaatatg caaactatcc ataacttctt cgattgaact catataatcc caccagtgaa
16801 tgtaaagtat atcaatccaa tcagtttgca atttgcggag agaatccctc acactcacat
16861 gtaaactacg cttgtgatta ccacagtagt tggcactttt accaccacct acttcatact
16921 tcttataatc tccggtaaac ttggtggcaa ttacaatctg gtcacgcagt tttcttgatg
16981 ccatccattc acctatccaa atctctgact cttcattttg gtaactgttt gcagtatcaa
17041 tacaattacc tccagcttca taaaaagcat caagaagttc aaaggcctgt tccttattca
17101 tagagcccat aaagcctgac catgcgtcgc cgattgaagc tcctcccaga attagcggtg
17161 aaacccttat gccggcagtt ttagaaagaa ccctgagacg tcccaattcg gtaggtggtt
17221 caggtagagg tttaaacaag tcagtcatgc tgaatagtgg ttttttatgc aatagacaat
17281 atgttaagta aaatacaaag ccgttcagct aattggttag ctagttaatg aagagaagaa
17341 cagcatgcat ccttgacttg gaaatattgt catacttaaa tatggttgga aattttgccc
17401 cccggtttcc ttgaatacga acaatgcaac ttatttgagt cttcgtacga gatctgctta
17461 ctggttttgt acagcgctga aagcgaattt gaaaatatat gcaattagaa gagagtgaat
17521 cagatgagga tagggttaat actgtaaaat tattaccaaa tattgaatga catataaaag
17581 tcgtagtaac cgaatttgtt ttttattatg aataaagact tcttgttttc gcatacttcg
17641 atgatttaag aaattaaaag tcatttaccc aggcgtgatt ataaattata ttggcaccgc
17701 tttatcaaca gcggtgggac gagacgttta gatagtaatt acaatagaaa tacaactgtt
17761 tcaatattaa aatatctcta gtatgtaaat aacacatata ggcaattttc ttcgaaacgt
17821 atgggacgcg gttgatgtat gaacggaacg catcaattaa aggtttgaga aaagtctttt
17881 gcaaaaaaat tgagtttgca cttctcatac acaattggat agcgtcttaa gtgcctttta
17941 ttcacttttc ttcttttgtt tcacattatt tatattcgta tatacttcca actctttttt
18001 tcaatagaat tcattgtcat gctcaacatg taggtccctc gcatattgcg aaccaccctt
18061 cgtatcttta gcctcggcag aatcttcttc aacatcaccc aaatcttcgg catccctagg
18121 tgtgtgattc aactgaacac taggggcata ctttgtgttt tccaaattag caaatatatt
18181 ggtcattacc ttgtcaagat attcgggagt atttacattg aacatattcg aaggtctaac
18241 acttaactta taatctggac cgtaatattc gtaatattca ttgtacggta aatctttatc
18301 caagacaacg ttatttagta gacctgtttc aaagcaccat gtccttgcaa catttctcat
18361 agtatagcct cctccaccaa caaccatcat tgggatccca aaggatttca catagtttac
18421 acaattagca tggccttcca tggaaagatt aaagcaacca agacgatcgc cggacaagga
18481 gtccccacca cactgtaaca cgacagcaga aggttgatac cattccataa ttttttttat
18541 cacaggttca aacacagatc tatacgtagc atcgtcaata ccgtctctta atggcacatt
18601 gaccgcgtag ttttttcctg cacccacccc tatatctctc agttcacctg tgccagggaa
18661 aaactcacca tatttgtgga aagaacatgt catgacacga tccgttgtat aaaacgcttc
18721 ctctacacca tcaccatggt gcacatcaat atcaatatac agaactctgg ggtggtatcg
18781 tagtagctca ataatgccca gtactatgtc atttaaataa caaaacccag aagcttccga
18841 tttttttgca tgatgcaaac cacccgcata gttgacagca acatcacatt tgcctctatt
18901 cagacgagca gctccttcca tagagccacc accagatatg ctacagtact catagagccc
18961 atcaaagaca ggacaatcat ctccgacatt aaacttgaca ctttctcttt taaacatttc
19021 taaattatct ggagtaaccc tcgataaaaa atcaatgtat tcatcagtat ggaactgaca
19081 catttcttgt ttcgttgccg gcttagctct gtaaatttcc atcttcttgt acaagccata
19141 attcataata agggaatgtg ccattcttat tctatgcggc ttcatcgggt gacctgctcc
19201 atatgcatag ttcccaacgt ctgcatcgta aaaatatgca acgcgtcttt tatcgcttgg
19261 cttgaccgtg atcggatcaa aaggtgttgc ttcatatacc atctgcacgg atatcgagtt
19321 gtagccacga atgttttgta tggcgcaatt gttttatgaa cctttatggt tattacttca
19381 aatttttatt atgtataatc aactactagt atcttttctg tttttccctt tcgatagata
19441 ctatgagccg gggagggtaa gtaaataaaa agataaattt caaggcaaaa tatgggacat
19501 atatttacaa atttacctat acgctctgag ttgatattac ttaagcacct tcaaaattag
19561 ctctcaccgc ttcataatga ttcagttcag cccgcgacac acttggggtg agctgctctt
19621 gtgctttcaa gaagtcttcc atttttacga caaccttagt atcctctttt gtcgcaatct
19681 tatcaaacca gcgacgtgta gaaatattct ctcccgtcaa ttcgttatgc tgagaaactt
19741 ttttttctac catgcgtgca attcttgaca tggcgttaag cattgcatct gagcagagag
19801 cataaaaatc tgccccggtg taattaaatg gacatagctt tgccaactca ataagcttta
19861 cgtcgttgtc gagcacgaat ttgcgagtca gagcctctaa aatattcaat tgtttggtat
19921 ccgtatccgg aatgcctaaa tataacaatt tatcgaatcg tcctggtctt agtagtgctt
19981 cgtccaataa gtctggtctg tttgttgctc cgataacaaa tacaccgtca gcgtcggtac
20041 tcataccatc taactctgct agtaactgtg aaacgatacg atccataaca ccacccgaat
20101 caccttgatt accacgtttg ggtgctactg aatcgatttc atcgaaaaat atgacacaag
20161 gtttagcctc tctcgccttt tgaaacactc tgcgcacatt agcttcactc tcaccaatgt
20221 acatattcaa cagttcaggg cctttaacac taaaaaaatt taaagaaaaa tttgttgcaa
20281 tggccttagc cattagagtt ttacctgtac ccggtggacc ataaaaaaga ataccgcttc
20341 tctttttcat acctgaggta aataattcag gatgttttag cggcatgtct attgtgtcca
20401 atatttcacc tttaacaaaa tcaataccac ctatatcatc ccaagttacg ttagggattt
20461 gtggggcacc aatcgaaacc gagaattcgt tcctagcttt cgaagtagct tttgataaat
20521 cctcctgagt gatcaaaatt gattgcggaa gccatccaca cttctttgat tcttggtaaa
20581 aacgcgcagt agccgtcatt cgtgccgttt ccacaattga tttgatgtct aaaggagtta
20641 aaccagcaga atatgaagag agtgatgaaa atgaaatatt atccatgtaa gatactggaa
20701 ccttttgttg aacatctctg tttagttcat gtgaagataa gtaccactga aagatacgca
20761 gtctctgtgc ttcagacgga acgggtacga gaatctcaaa tctcatatgt gatctaaagc
20821 tggaaggcac gttatctatg ttatttacgg agccaacaaa tgtagttcct gggaatttaa
20881 acgtaaaatc gtccagaagt ttagacattt cgaagtttat agatttttgt aatttgattg
20941 cctctggatc ttgattagcg tttacgtcaa gcaaaattga atccaaatga gccaaaaaaa
21001 tcacagcagg tgatgcgtac ggtaggacat tttcacattt agccctaatg taaccaataa
21061 tcttagatgt tgaatccagt tgtcttgaat ttgaagtgag cgaaaggcaa tctatctcca
21121 gtagatgtat accaagatat tttgaagcaa atctcaccat tgtagccttg cccacattgt
21181 ttgtagtgga atgaagtaac acagaggcat ttagggtgat tcccctttga gaacaattga
21241 aggaagtttc taatatgtta accaattgtc ttacataggg gaagatatgc aaatcatagt
21301 aaaaagtttc agcaaaaccg taatatctct gaagattgga tctactcaag ggtaatggtc
21361 ttctgttagt gatattagtt gttattagct tcgtccgatt gggatcaata ataaaatgag
21421 aattatcttt agagaagcaa tcgagctctg cgcttgtgac aaagaaccat acaagggaat
21481 cgttcttgta gtactgccct agctcatctt cgtcatcaga ctcatcattt tcctctgcta
21541 tattgagatc agccatactt gaatcaaaag cgattgggat taaatcattt tgacaaagaa
21601 tccttttgct ctcgctaaaa aactttttca aggttgttag aataatattt tgaaagcatt
21661 tctgagattg aagccagcct ccaactcttg agatgaaaac ttgattagca atgggaatat
21721 ctgtatggcc tatattggac tttgatattg tcacgacgct gcagtctgga aagcttgcta
21781 ttattttggg aggtgcgtat attgttcttt ttttaaagcc gttggggagt agtaaaacaa
21841 acagcttaac tagcctgacg caacccatat ttgacactgt tataaacgat ccacttgtga
21901 catccaggcg cagtagagtt tcagcgtctg taaaggcata tattgaatta tcatcattga
21961 tgtgaggtgc aggtcgcaaa agatctcttg aaattgtgca ggggagagat tcaagatcaa
22021 ttgataaagc agaatttgtc cctattttag gtaatgcata ttcttcatct tcgttagcat
22081 attttagagc acttagtttc tgctcagtat catttactaa tatcaattgg gtttctgtaa
22141 aatcaacaag gccctgcggg aaaggtgagc agtttaaaat ttggcaaaga ccagatgtta
22201 aaatatctcg agaatgaacc acggtttcca tggagttgat gttatatttg taatgcaaaa
22261 attgtatttg ttgcatctct tgcggtaggt ccattagttt tgagtacaat tgttcattaa
22321 tcagaaacgt tacgctatcc agtacaggta ctacattgtc taatatgggt tcaaaatagc
22381 aaaaatccat agtgggctgt gtcggcataa acccaaaaag tttggaaggt acaacaatgc
22441 tacagaaggg cagtgaatca tccaggacac aatgtacaat tttaccaggc gtgcaacctg
22501 gaccgtactg aggcaatcta attgtcccat ataaacattc agctttttta tcgccgtatt
22561 cgagatatat atccctagaa atgctacagg gggcgtatat tccggagaga ctaaacgtaa
22621 gcgatgcctt catattaatg ttactataat cgctttcttt tggagggtat gcaaacacat
22681 atatgctctc cactactgtt ctttgttcta attctaatga cttgtttgaa agtctccgat
22741 ggccgcactt tcccggaagt gttgacgatt atcgccgtat actatgtggt gtaaggaagt
22801 gtagcaattg gctacatgat atataaagtt cttttatctc tttcttagta aaacacttct
22861 ttcgagaact tctttcgcct catttatctt ggccgccatg tagggactcc ctcctctgtc
22921 tgggtggtta cgaaccatag ccttcctgtg cttttttttc agtaattttt catccaagtg
22981 attaatctct ctggcggaga tatccaagat gagcaaggct tcgggctctg tcattcgcgg
23041 tgcaaagcct ccctggtact ggtttaatct atttttcagt tcttcgtcta tcagtgagct
23101 tttgaactta agtgcatcgc ggtagcccgc cgtcgggttt tctatgcgaa tgttatttag
23161 ttttgcaata gttaaagggg acagggtctt gtagacggtc catgcattga gaccagactt
23221 gacacttaga gcaaccattg tcacgcccaa accaattatt ataggcaaaa ccatgctgga
23281 atatcctatt ctttgtggct atactgtgta ttgagtggat cctagcaacg aattcgtttg
23341 ttgttatttt tttctagatt gtatctccgt ttccgaaatt gttattcaca atgagcgttt
23401 acctcttgca ataacaataa tcagagaata agctacaaga cgaaaaatga cgttgagcgt
23461 ggcagtaatg ccataacgaa gatcaatagt gtatgggatg ttggatatgt cgtttccctg
23521 ccaaagaaaa agaaacacaa aaaagaaaaa gcaaaaaaaa acagtgctaa ggatttgata
23581 ttaaacgaag tcccaccatg gaggatcata tcccaataaa tttatgcata gaatggtacc
23641 attcacaact aatatagcct ctgctggttc ctttagtaac ctctttagta acctctttag
23701 tgaaatggtt cttgctggct ctattatttt cctaattcgg acgcgctggc tccgcgccgt
23761 gaggaaaaac agcaggctga caagggacta atttactgac actttcggct gacacttccg
23821 aaaaggtact caagctttta tgagtaagat gctggtttga tgctaagaat acgatttagt
23881 acttcctttt taatgtggct tgtttttttt ttattcgtcc ataacagtac aaatataaaa
23941 gcagaataca ttcttgccga cctaaaactt gtgtccttag actcaaactt tctgatggtt
24001 ttctttcagt agaatcaaca taaacaagca taatataaaa cactacaatg aataaactat
24061 tgttacatct agtacgagtc atttcgatac tcggcctagc aaacgctctc acacaaacgc
24121 aaccgatttt aaaagatatt caaataacag atagttatac caaaacaaaa gaatgtacgg
24181 atccagatca ttggttcata atagaagggc aactgtctat tccaaaggga agtcagcaaa
24241 atataacatt ccaagtacca gatgctttca gctcattccc tcaagaaccc ttcagcataa
24301 aacataattc taacagtgtt gccacgatat cacgcccaga taaatcgacg aacaatttca
24361 ccatttctat tccagaaaag agttcagaag atataactac tacatttaac ttccttgcac
24421 agcttacatc agatgctaaa tccaaagtta cagaaccaaa aagcatcgtt tacagtttct
24481 attcagaaaa tactatgttt aatgacgtta ttgattacgt cgctaaaaat acttctgcta
24541 taacaacaga tggtggtata tacaaaacta ataataccgc ctggtttacc gttgacttac
24601 caatgagaac gttcagaaat cccgtttatt tgacttctca gacatcttcc tcctcagatt
24661 acgtattcga tacttcgtta actaagtttg aggttgtcac tgccgttgat tcttttaacg
24721 aacctattaa tgctatccca tatacaactg ttcatgacta ctccacagaa gatgaaatta
24781 gatgtttatt taattctaca atcagcggtg ggctatactt ccgtgtgact tatttcacaa
24841 agaagctatc tacctcgtcc atatcaaata ctgtcgaatt aacatatccc gatgaaggta
24901 catctgtcag acttttagga aagagagata cttcaaccac cctagcctca gaattatatt
24961 ctgagtcagc tgctaacatt gattccacca ccagtgatga cacaactagc tctgatgctg
25021 ctataacacc aacatactca aattcaacgc tttcttctta tacttcgcaa tcatccgcta
25081 tccctgaagt tgcggttact gcatcattga gtagcgggat cctttcttct acagttgacg
25141 gtgctagcac ctcggcggac gcttccatgt ccgctgtctc tacggtttct tctagcagtg
25201 aacaagcttc ttcttcaagt atttctttat cggctccaag ttcttcaaac tcaaccttta
25261 ctactccttc atcttctctg tctgctactg aaacatatag tattatcagt tcagctagta
25321 tatctgtcac acaggcttcc tacattgata attctacaac taccgctgtt acccaatcta
25381 cttctactat agcagtttca tctgctgaaa aattgtcaag cactctatca tacaccagta
25441 acgtcacaat atcagtatca tcagctaccc aacatactac tactccttca tatgttagta
25501 actccactac actctcatcc tcatctgttc ttgaatctgt aattagctct ccatacctgg
25561 caaacactac tgtttcagga gcttcatctg caagtcaatc tactaatccg ccatatgtct
25621 ccaactccac aacatcatcc gcaactcaat tagccaccat tgctccgttc gcgattaaca
25681 taacaggaac aagtatttct tctagtatca ctaatacttc ttcagttagt tctactacgt
25741 ccagtttatc atccggccca tttgtttcaa acacaacggt tgcctctggg tcttatattc
25801 taaccactac tacagagtct gcacaactta ctgaaatagg gagtttgata ccaatctcga
25861 ctattactac tagtaccacc acttctggta ccgataaaac tggtagtaat aaggtggcct
25921 cttcaactga aatagcgcaa tctatcgtaa acaacagttc actttcggtg tcaacaatca
25981 acactaacgc tgcgacagca gctgctaatg ccagaaatgc tactttcact catgcaaccc
26041 attctggttc gcttcaaccc tcatatcata gcagctcact attatcgtcc acaattgaca
26101 ccaaggtaac tactgctact acaagcacca gtagagacgg tagttcgagt ttggctttca
26161 ccactgggct caatcaatcc gtagttaccg gtacagataa aagtgatacc tatagtgtaa
26221 tttcatccac agaatcagcc caggttacgg agtacgacag cttacttcca atttccaccc
26281 tgaagcctac agtcgttaca ggtacaagta gaaacagtac ctttagtatg gtgtcctcca
26341 ccaaattgac cgaagctact gcaacggata aaggtgatgc gtatagtgta atttcatcta
26401 cacagtcggc tcaagttact gaatatggaa gtatgcttcc aatttctacg ctggaaacac
26461 caacagtcat tatgagtacc gatgaaagcg gctattttac tttaactaca tgtactgagt
26521 ctgggcaagc tacagaatat ggtagtctga ttccaatttc cacactagat ggttcagtta
26581 tatatacatt tactggcgaa agtgtagtgg tgggttacag taccacagtg ggtgccgccc
26641 aatatgcaca acatacaagt ttagtcccag tatctaccat caagggttcc aaaacttctc
26701 tttcaaccga ggaaagcgta gtggctggct acagtactac agtgggtgcc gcccaatatg
26761 cacaacatac aagtttagtc ccggtatcta ccattaaggg ttccaaaact tctctttcaa
26821 ccgaggaaag cgtagtggct ggctacagta ccacagtaga ttctgcccaa tacgccgagc
26881 acacaaattt agttgccata gatacattga aaactagcac attccaaaaa gcaacagcaa
26941 ctgaggtttg tgtcacatgt accgcccttt cttcccctca ttctgcaact ttagatgcag
27001 gtactactat ttcattgcca acaagttcca gcacatctct atctacaata attacctggt
27061 attcctcatc tactattaag cctccttcaa tttctacata ctcgggcgcc gctggtcaat
27121 taaccatccg tattggcagt ttgttgctag ggttaatctc atttctgctg taagaactat
27181 tttatcaaat agaaagttat aaataaaaac taagagttct tttggtataa tgcataaata
27241 atttttttat ataatgtttg taattgtaat gataaatttt tatcatcttg gataattttc
27301 gtattatcgt aacattcatt cgttctagtt ttatgactaa tttgcatcga taatttctac
27361 agacgcccta tcggcttcta atgagggtct tggtgttact cttctcagta attgatcttc
27421 taaacatcta ctacttagca gtcggtcttg tacttgaggt cttacattaa aatataaacc
27481 tttttcatcc tttgtgtgtt tagacttttt gtacttgaag gtctcaatag gaagtatcca
27541 ctctaaccaa gatgtaccca ttatatcttg ccagttggcc attgaagaac ccaagtcaaa
27601 tatattctct aaatgctcat ttgttccata gctgtcattg aggatttcaa gatcccttcg
27661 ataccttctc attccgtgta cctcgatagt agtttggttt ttacaaacct gataaatgct
27721 gaaacaggta aatgctaaaa cagaaatgaa aacagcaacc gccaataggg ccacccctaa
27781 tagatgaaaa tctatcaatt cacggttgaa actaccggag ttaaaccacg tcccaagctc
27841 atagcaagta taaattagga ctaagaacgc gtataatgtt gtgtacatta agaattgaat
27901 aaaaaatttt tgattcctaa aaccagtgca ttcagcgaac caagggcaat gatgatccat
27961 tttcaatatg caaacatcgc atgatgaaca atgatgacag cgatcgggct tccaaacatg
28021 gcatacttgg cacacccgaa atcttccatc atgttttaag gtcaaacacc tttttgacat
28081 atactccgga ggaagttcaa gtccattttc cgctgccttt aaatcgtgga ctaacaaatc
28141 agggaaatct agaggagaac cgggacctct agcaataacc ttataataag tgtatagagc
28201 cactgccaat gtcggaacta ttgttagcgc gagaaaccac ctaggtattt gatgaatcct
28261 tgtcaatgtt atgtatgcag tccaaatata caaacatgtg gtcaaacacc tgggaaacag
28321 acttgtcaac gaaagcctgt cattcatttg cgaaaaagat tctatcgaat tccaagatcg
28381 gcttctttgt cttgtatttg gtacgactta gttatatagg tttttttttt tttcttggac
28441 gcaatcacat aaaagtgtaa tatatctcat tagacaaaat tggaaaagtt agataattag
28501 cgtaaaagcc ttcattaatg ataatagcgt gggaggtata agatgcgctt aataacgctg
28561 aagaatataa agtttcttat acattcaatg aaacaaggaa attttcaatt ttaaatttaa
28621 gttgaaatag cctttagcac ctaaaaataa aaaaatatta aaacaccaac atgttgttga
28681 acaagttttc cagagaattg accgaatatt taaatttcta tttaagagtc atataaattt
28741 attgaaaatc aagttgtata tctttagaaa agcacaaatc cctgtaaagc tgcaaattgt
28801 cgggcttaat gtgtataaca gcagaatagt catcaagagc aggtttataa tcatcgacat
28861 tgaggacttt ttcgtaaaat ttttcgtcaa cagacacatg atcaggagca ataagaagtg
28921 cttctgttgt catctcgtca ttctcatcgt cgccatcatc atcatcatcg tatacatcag
28981 tgaaatcttc tgcaatatca actagtggtt ctcctattac ttttctcatt ggtggaatct
29041 cactactttc atgactgata aaaattggat attttgaata cgaaaatgaa ttcattttct
29101 cttccaactt ttggcttctg tcagatatta tgtgcaggta atgttcatac aattctaatt
29161 cttgctttgg agatgtatct ctgtctaaat cggtagtctc aactacccta ccttcagcct
29221 tttctaaact cttactggat gtgatcatct ttagcttatt attcagccaa ctttgcttcc
29281 tagaagtgaa cggcgacata gccttgtctt gtttggacaa agcattatga tatcttcttg
29341 ttgaattcat attatatgca aagagatcgc gaatccaagt tactgatctt ggcagataat
29401 attcattcca gtaattgtca aaggcaccag gataacctct tacgtttttt ataattttct
29461 ctcttgtcac atcattacct gttgcaataa gttcttcatt aatcaattct tttacacttt
29521 tgatgttgta atcattccac caatgaatat agctcctttt aggcatatta agactataag
29581 cattatgcaa gtagaaatcg gtattcattt cccataaaga gggaaatcct tctctccagg
29641 agtagtgacc caggaataaa ttaatcgcat cttgcctttg tgcatcaacg aatgaattac
29701 tgtagaatct ttttatactt tcgatcatat cccttgaatg ggagctccac tgatttattt
29761 ttctatatgt ctccatggtg ttaaccaaat gcgaaccgcc atattgtaat gcaatagtat
29821 ctcccagatc atgaaacaat tcagttagta tgttgacgat atcagagtcg tactctaaat
29881 aactattatc gataattcct aaagatttga gctggcaacc aagtgctctc ttgccaatga
29941 cgaattgggc ggcgttggtc ctatcaagac agtcaataca attacttcga catattcctt
30001 cctggatctt tgtagaagca aagtctggac cattatgaaa tattcctgtc gtcgtgacag
30061 tgtttaccgc gtacttctct aagaattcaa taacaccttg accatcttgt ttagaagccc
30121 tgctcatatc ccaagaggtg taatctaatt tctttagtgt tggtaaaaat tcattcagat
30181 aatctataca ttgttcaaat tcccagagta acttagtttc tcttggcgtc ttttctttgg
30241 ttttaattaa gttcagtatt tgaatggttc cgccaccata tctttgaaac aagttatcaa
30301 aatgcaacgc agccggagaa aaaaatggat ctaccacatt gattcttata ggtggctttg
30361 tggttaaatt ggacgcatcc tgggtccagt ataaggggat tgagccacga tgctgtacaa
30421 aagaagtgta tcgatcacta tcaaaaaatc catttcccgg ttgatggaat ggagtcaaaa
30481 tcatatctgt tacaatctgt tcagtttcga cttcgttagc aacatgacct ttattgttaa
30541 caccacgctt tagaaagcgt gcaccagcaa aatggtggga tcttcttgcg attaaagtaa
30601 tatatatgga cttacccaaa actgaaacat taacctggtc aataaatcca tgtataatgc
30661 attggaacca atcaaaaaca gtgtcaatac aagcaaaaat aggagataat aaattgttat
30721 tccaaacaaa catttcgtta tagtcggtta tcccgcaagg tattgtaata tcacatcggt
30781 caaccgcttt taatttctct cgcaatatat tggtttgtaa agtatttgtg atatcgtagg
30841 tataactgaa ataaaaggtt tttgttaggt ctaaatcctt aaatatattc aatagccttg
30901 cctcatctga acttttttca ggttttttat agttgttcgt aataggaata atatcaatac
30961 catcaatgtg ataaatacca tgaccgccaa tcactgcaac ttggctatac ttggtaacca
31021 ttattaaata gtaccaacag gtgaatttaa tgaatcccag aagaccgtat cctgtaattt
31081 tcttatgtag accatcttca gttgcttctt ctaaacttgc tagtacattc atgatttcat
31141 ttctggtgaa gaagacatta tcctccaaca cagttaattc tccacggggt acagtaagat
31201 caatttctag aatacgaaac atggtttccc ttttattgct tccaacaata tacattcgat
31261 ctttggtttc gtataacgta tatttaccca ttacaaactt agaggtcttt ctctgcttag
31321 acccagatgt ggtaagtata cctccaccaa gggtatgctc cattgcatca ttgttcatcc
31381 ttgtcctgtt tcttttttgc tttgcgttac gttactacgt ttcaaaacta attaatttca
31441 aataatatca cagcatttac atttcaatag tgctcggcta agtagatgag gactatcgta
31501 aagagaccaa tagaagagct tgaaaacttt acaagaaata tatacatgta tatattatat
31561 atatatgttt aatgcaattg caagaggtat taacaaatca ggaggacaag taaatgaacg
31621 tgctgcaata aacccaaatg gcgtaacgag tgtagtgcgc cttagtgacc accgcaagat
31681 agtgccagta actagtgtac aagtgtggca aaatgcaaat gagcgttctg gtagtatgtg
31741 tccaatgttg tagtgtcaac tttgtctgcc gttctggtgg cttttgacag ttgattttcc
31801 aacgattatt attatgcgcg aaattaaaga aaaggaatct tgtatgatga taaaataaat
31861 agatcaaatt aaatcatcag tacagaccag aaaacaatta agtgtccttt tagaaatacg
31921 agagggtggt aaaatattga agaatggtaa atttcgattt gggccaagtt ggtgaagtat
31981 tccgtagaaa ggacaaagga gctatagtgt ccggagacaa cccagaagaa gaagaagacg
32041 tcgatgcttc tgagtttgaa gaggatgaag taaagcctgt gcgtacaaag aacagaagac
32101 ccaaagagga tgcattcact caacaaagat tagcggctat aaacccggtg ttaacgccga
32161 ggacagtttt gcctctttat ctgttaattg ctgttgtatt tgttattgta ggagggtgca
32221 tattagcaca gaactccaaa gtggatgaag taaccatata ttaccaggac tgtatgacta
32281 acgcaacctc atcatggagc gacatccctt ctgaacattg gcaatttgta tttcacaaat
32341 ataaaacata taatactgca ccacaatgga ggtttgtgga tgatgaatca gatgacttca
32401 caaaacaaag aggtacatgc caaatcaggt tcactactcc aagtgatatg aaaaataacg
32461 tatatttgaa ttatgtgctg gaaaaatttg ctgccaatca cagaagatat gtactatctt
32521 ttagcgaaga tcagatacgt ggggaggacg cctcttatga gacggtgcat gatgcaaccg
32581 gtataaattg taagccacta tctaagaacg ccgatggtaa aatatactat ccatgtggcc
32641 taattgcgaa ctcaatgttc aacgacacgt tccccctgca gttaacaaat gtaggggata
32701 cgtctaacaa ctattcattg acaaataaag gaatcaattg ggaatctgat aaaaaaaggt
32761 acaaaaaaac caaatacaat tatacacaga tagcacctcc accatattgg gaaaagatgt
32821 atccagatgg atacaacgag acgaatattc ctgatattca ggattgggaa gagttccaaa
32881 actggatgag gccaggtgct tttgataaaa ttacaaaact gatcagaatc aataaaaacg
32941 atactttgcc agcgggtgaa taccagttgg atatcggtct gcattggcca gtattggagt
33001 ttaatggtaa gaagggaatc tacttgactc acggttctca ccttggcggt agaaatccat
33061 ttttaggtat agtttacctg attggaggct gtatttgtgc tgccatggca ttgatattat
33121 taacgttttg gctcttcggc ggtagaaaga ttgctgatgc atcaagtttg tcatggaata
33181 tgaaatagaa aaggagtgat ggttttcttt atttttaacc ctgtaaaatt tttttatttt
33241 tttattttta ctcttatata tgtatatgtt tgtgtttatt tctgaataaa aatttataag
33301 aaccaaatta aaaccgttaa tagcccaccc aaaattgaag taaacgaact catacctaga
33361 tgctgggcct cattatgcga aactgttttc tttattgcag atttaataac gcctacagta
33421 ccggttaaag tacccatccc aatagacccc acggagggag aagcgactgt tacgtactgg
33481 gaggagaaac gctggacaaa agtagtttgc acagtgatag tgttgccctg tctaacaaca
33541 gtgacccaca tggacgttgg cgcacgtgtg gttgtgtaag tggaggttgt accttcagtg
33601 atggtaatgt atgagtcaat agatagacta gtgacagcag acacaggagg ttctgtgaag
33661 tctgtggagg ggtctggcct ggtgcctgtt tcagctactg cgctccctgt cgatgtggtc
33721 gtctttacac tggaggatga accagacgaa gatacagacg aggacacaga cgaggaggcg
33781 gatgaagtag cactggtgct agaatgtgtg aacgtttgag tcaatgtaac tgtggtaccc
33841 aaatcgtttg tcgtggtaac tgtagataaa tacagtcccg aagacaacga tgaagttgcg
33901 gtaggaacag tggtggttgt cttaccagta gatgaggtag aagtcgtcgt ggttggtagc
33961 atagtggctc tgttgactgt ctgagtaaga gtgacggtgg ttccgacatc gttagtggta
34021 gtgaataccg tagtgaagaa acctgtttga gcggtagttg tagcagcagc agcagcggtg
34081 gcagggtccc atattgtggt ctccgtaacc agggcccctg cgacatttgt taccactgta
34141 acctgagttg tcacagctgc catgaccgca gctgaccaca acgacaaaga aagtagcagc
34201 gtagcgaatg aatgtaatag cgtgcgacgc atcatttttt ttttgattgt cttgcagaag
34261 ttgaagaggt ctttactgta gcatatacaa gtgcttaatt cttgattttt attttctttt
34321 tttcataata cacgttatag aaaaagcccc attctcagtt tatgaaaaaa cgcgatatca
34381 ccatacacgc tgaggtaggg ggatacaagg tgaagaatgt acgcaataag gcgaagtata
34441 tggcacaatt gagcagtaaa agtgttaaaa tatagtgata tatatatata aaatacgaga
34501 gtaccaacta ttatgatctt ttaatgccct ctttccgttg agatattcat aatagtaacc
34561 gtcacggaac tgtcgcttta tacggtgagg ggattattta gttcctaatt tatattagat
34621 aaagaagata ataaacatga gggatgctgt aaatgaaagt gaaataactg ctagctagaa
34681 gagcggtaag cagcaatggc caaaaataac cacatttctg ccagtggtaa cagtacctct
34741 ggagaccatc gtcttaaaga ggaggttctg accccaacta catctgcctc gactcctcat
34801 agaatattta gcgtggacga tgatccaaag gagatccaaa acgatatcag gtatcttgag
34861 ggtctgcatg aagggttgaa gttcgccctg catgccaata aatccaagcg atctgtaagc
34921 tcgcaatcac caatcgtaca tagcagcaac aacacgctgc accaccacga gcaccaacaa
34981 cacttgccgc ccacactaga gtcgctatcc tccaagtcgc actctgtgcc agacttaaat
35041 acagctactc ccagctctcc gaaacgaatg cattcatcta tccgggaatt acctcatgat
35101 gacaatgatg acgaggacgc caatgatgac agtcggttca ttatacacga ctcgcacggc
35161 catgatttac ttatagacga gatcaattgc cagtcgcctt cacacttgga aaacaatgac
35221 caggcgtcta atgcttcgtc cacagagtca ttcactttac gagaaagaca ggacgccatc
35281 aacgagaccc accccttcgg tatcaggata tggaagcctg ctttatataa gaaacaccgt
35341 tcagttcaaa gaaccgcggc gcaagacatt cacgagactc agttgaagac tattacctgg
35401 gaggtgactt gttccaatgt gctatggttt attttgttcg gtttccccat tgcgatactc
35461 ttctactcgg cggctattgt ggtattttta ctaggcggcg gaggactggt aacgaactct
35521 gcgaaggagt actccaagtg tctgtataaa ctcgccaatt atttcctttg gccttttggc
35581 aaaatggtat acttgttgca ggacgagcaa tatttacaag aagataagga tgaaggtatt
35641 agtatgcagc aattctacaa ttgggtgact tcatactcca acaggctggt cttccaccag
35701 tctcaggcca agtttcagca aagagaggac catccggccc ctgcaacgga atcttcgtct
35761 ttgatgccgc ccgctaacac aacagcaaca ccgcttaact cgaaccatcc atcatataat
35821 tctattagac acgaaattcc gcacgcagcg gctcaaagac ggtactttgg gagaggaaaa
35881 tggagctggg gtcgtgttct tttctataca atcttccatc tcgtcttgca acccatcctt
35941 gccgtcttat ctctttgcct ctggctcctg gtgtttacca ttcccatgag taatgttctt
36001 tggcaaatta tgtatcattg cagaagacat ccgcttgcat taggcttcaa atatgtcgag
36061 aactcctccc aatcgcacga aaatgaaata acccagcagc aattgaacaa aaatatcctc
36121 ttatgtacgt tccgtgccgc tggctggcat tactacaagt acacagttga tggtacaaat
36181 gttattgttg tgaatttaat atccatcgtt ttctttacaa tttttgactt ttatgttttg
36241 aaaaatttcc tgcattggaa aacgtggttc acatacgaat cctcaatatt cattctttgt
36301 ttgacatcca ccatcccact agcattttac attggacaag cagtcgcatc gatctctgct
36361 caaacttcca tgggtgtcgg tgctgtcatt aatgcatttt tctcgaccat tgtggaaatt
36421 ttcttgtact gcgttgcatt gcaacaaaaa aagggtcttc tagtggaagg atccatgatt
36481 ggttccattc taggtgccgt tctattatta ccaggtctgt ccatgtgcgg tggtgctcta
36541 aataggaaaa cacaaagata caaccctgct agcgctggtg tctcttccgc attgttaata
36601 ttttccatga ttgtaatgtt tgtccccacc gttttatacg agatatatgg cggctactcg
36661 gtaaactgtg cagacggtgc taacgaccgt gactgtactt tctcgcatcc tcccctgaag
36721 ttcaaccgtt tattcactca tgttattcaa cctatgtcca tatcttgtgc cattgttctc
36781 ttctgtgctt atatcattgg cttgtggttc acccttagaa cacatgcaaa gatgatttgg
36841 caattgccta ttgcggaccc aacctcgacc gcaccagaac aacaggaaca aaattctcac
36901 gatgcaccca attggtcaag aagcaagtct acttgtattt tacttatgtc tacgctcctg
36961 tacgcaataa ttgcagaaat ccttgtttcc tgtgttgatg ctgtcctaga agatattccc
37021 tccttgaatc caaagtttct aggtctcacc atttttgctc tgatccccaa tacgacagag
37081 tttttgaatg ccatttcatt tgccatccat ggtaatgtag cgttatcaat ggaaatcggt
37141 agtgcttatg ctttacaggt ttgtctttta caaatcccat ccttagtcat ttattccatt
37201 ttctatacgt ggaatgttaa aaagtcgatg attaatatca gaacacagat gttcccatta
37261 gtctttcccc gttgggacat atttggtgct atgacgagtg ttttcatgtt cacctatttg
37321 tatgctgagg gtaaaagtaa ctatttcaag ggttccatgt tgatattact atatatcatt
37381 attgttgtag gattctactt ccagggagct ctttcggagt agaaagcaac tgtccccgct
37441 tttcacctgg atacctacca atttttcttt ttcttatatc tttgtattgt ttgtctttct
37501 tattactttt tattctatat agtctttagt taattaatta cccgcaacga tcattaacac
37561 ctcttaaatt gatctactca caattgggtt gttcttatac ttagagaggt gcgttcctcg
37621 aaataactcg aatcaagccc acacctgctc ccttttttat ttctccgtca attgcactgt
37681 agaatccttt tctggtctca tgttgtggaa agtttctaag atgttcttgg gtggcttggt
37741 agcgctaaca acaatatcgg ttgcgaccct ttatcactac caaaatcgcc tagtctaccc
37801 atcatgggct caaggcgcca ggaatcatgt tgacactcct gattcccgtg gaatccctta
37861 tgaaaagcta accctaatta cacaagacca cattaaactc gaggcatggg atatcaagaa
37921 tgaaaactca acaagtactg tgttgatctt atgtcccaat gccggtaata ttggatactt
37981 tatactaata attgacattt tctatcgtca gtttggaatg agtgtattta tttattcgta
38041 tcgtggttat ggtaactcag aaggttcacc cagcgaaaag ggtttgaaat tggacgctga
38101 ttgtgtcata tcgcatttgt caacggattc tttccattca aagagaaaac tagtattgta
38161 tggtagatct ctaggtggtg ctaatgctct ttacattgct tcaaaatttc gggatctatg
38221 cgatggcgtt atactggaga atacattttt gagtattcga aaagttatcc catatatttt
38281 cccccttttg aaacgcttta cgcttttatg tcacgaaatc tggaattcag aaggccttat
38341 gggaagctgt agttcagaga cgccattctt gtttttaagt ggattaaaag atgaaatcgt
38401 tccacccttc cacatgagga aactgtacga aacatgtcct agttcgaaca aaaagatttt
38461 cgaatttcca cttggttcac acaatgatac tattattcaa gatgggtact gggatataat
38521 aagagatttt ctaatagaga agggttttat ctaaaagtaa taatcaaaat atttgataga
38581 tttatttact ttactgtatg taaagaaaat gtggtcagtc ctcacggcca cttagttact
38641 gatggttatt tattatggaa aaaaaaactg cactttgcta cttcttctat ttatattatg
38701 taatatctac tccggttcaa atattttatt gatctcttgc tcattctttt tcctcgtttc
38761 aggaactagt atccaactga atattatcaa cgctaatagg caagcagcaa atatgtatcc
38821 tagtttgaaa tcaattttgg atacaatcat tggtgttaaa agtgatatta agaaattgaa
38881 catccaattg ataaatgtgc aaatagccat tgatatggcc ctcgttctta gagggaacaa
38941 ttcggacact agtacaaatg taactgggcc caatgttatt gcaaaccaaa aaataaaaca
39001 acaagtcacg ataattaaaa caatatttga gaagtccgtt tctcttccaa atgtccccac
39061 agtagcatat gtcatcatat aaaataataa atttgttgaa ccatataata aacatgtctt
39121 gtggccccat ttctccacgt aatatatgcc taatatcgta gaaaggaagt taacacttga
39181 cagtatgatt gaagtaatat aaggatcctt aatcccgaca cctttgaaaa cagacgttcc
39241 gtaataaaag aaataattta ttccggacag ctgttgaaat gccattatca tcataccaat
39301 aatcagtctc aaccataact ttggctttcc cataataaat tcaaatgtgt ttcttttaac
39361 taagctttgc ttttttgatt cgttgttagt ttcctcatta ttatagttat tttccagcaa
39421 atcatcgatg aattcaatta ccatgctatc cgtcgcaggg atgccattca tcctcgcaaa
39481 agagtattta gcagagggca catcattttt gatttttgcc aagtactgtg gagattcagg
39541 aacgtaaaca agtgacattc caattataat tgcccaaatg tatcccaaga acaatggcaa
39601 ttgccaggct atattttgtg taggatcttt ataacatctt tcgcatatga aatttaaaat
39661 gtttcccatt agtatgccaa atgttacaat caattgatac gtagatacca tggagcctct
39721 gatttttagt ggagaattct cggagagaaa cattggcacc aagacagtgg ttactcccac
39781 accgattccc gttacggctc ttcccaatgt caaaaaatac caccttccat aggagagaat
39841 ttgaatggtt ataccgatgc agtacactac taaggcaaac catataccac ctttcctacc
39901 aatccaatca ccgatttttg acagagttaa agcccctacg ccacaactga tgttaaaaat
39961 actgataatt aggcctattt gcagatcagt aagtttctta gtagatacaa aaattgtttc
40021 atcgtcatgg ataatattag ttgtgccaaa tttttcttga aagctaacca tatttgtcat
40081 tccaccgatg gttccaatgt cccatccaaa aataaagcca ccaagcgaga ttaccaagca
40141 caataaaacg ggaatatgca gactcgcatt gtgactaatc tttgctgctt ggccttctat
40201 attttcttct ttatcatcta gatacttaat ggttacatta taatcccttc ccctgcctgc
40261 atcaagctca ttattgtgaa aatgagagat gtatcccgag ctatgttgat acggaatctg
40321 agcagtcatt tctagcaata attgaagtac tttacttcct aagaatacgt taacaaattc
40381 tttgttagta tttctaatta aaagtggtta attgttctgt taaacagtat tcaatgttgc
40441 tatttgaatt tgtgtcatca ttagaattac tgacattttt attttctatt tttttttcta
40501 ttttttttcc tcttcttttg agggccgacg tatcgatttg tcaagggaag tataattaaa
40561 gaaagcactg atatacaggt tgctgggtag atattaagaa gctcaacata gacacgttat
40621 ggacgggcat aatcagaacc agtaccagaa tcagaatcaa attcagcagt cacaacaacc
40681 acctctgaag aaatatgtga cacagagacg atcggtagac gtgagttctc cgtatattaa
40741 cctatattac aacagacgac atggattacc gaacctagtg gtagagccag aaacttcata
40801 cacaatagat ataatgccgc ctaatgccta cagaggtcga gatcgagtca taaatttgcc
40861 cagcaaattt acgcatttaa gctcgaataa agtgaaacat gtgatacccg ccatccaatg
40921 gaccccagaa ggcagaagac ttgtagtagc aacttatagc ggagaatttt ctctatggaa
40981 cgcatcttcg tttacgtttg aaaccctcat gcaagcacat gattcggctg tgactacaat
41041 gaaatattct cacgacagtg attggatgat tagtggggac gcagatggaa tgattaagat
41101 atggcaacca aactttagta tggttaaaga aattgatgct gcacacacgg aaagtattag
41161 ggatatggca ttcagtagta acgactcgaa atttgttacc tgttcagatg ataatatctt
41221 gaagatttgg aacttcagca atggcaaaca agaaagagta ttatcggggc accactggga
41281 cgtgaaaagt tgtgattggc atcccgagat ggggttaatt gcctccgcat ctaaggacaa
41341 tttagtaaaa ctgtgggatc cgcgttccgg aaactgcata tcatcaattc tgaagttcaa
41401 acatactgtc ttgaagacgc gatttcaacc caccaaggga aatctattaa tggcgatttc
41461 aaaagataaa tcgtgtcgtg tgttcgacat tagatacagt atgaaggaac taatgtgtgt
41521 aagagatgaa acggattata tgacactaga atggcaccca ataaatgaat ctatgttcac
41581 tctggcgtgc tatgacggct cgctaaagca ttttgatctt ttacaaaatc taaacgaacc
41641 tattttgact attccatacg cccatgataa gtgtatcacc tcgttatcat ataatccagt
41701 aggacatata tttgccacag cagctaagga tagaaccata agattttgga ctagagcgag
41761 gccaattgat cctaatgcat atgatgatcc aacttataac aataagaaga taaatggatg
41821 gttttttggc atcaataacg acatcaatgc tgtgagagag aagagtgaat tcggtgcggc
41881 cccgccacca ccagctacac ttgaaccaca tgcgttacca aacatgaatg gattcatcaa
41941 caagaaaccg cgtcaagaaa tcccaggcat cgattcaaac atcaagagtt ccacattgcc
42001 aggtttaagc atataaaagt gcgctttgac gagattttag gatacataaa taaaaagact
42061 atataacata ttatttgtga taatatctct catttctggg gaatgtaccc cacaggcacc
42121 actgtttact tttgtcgctg atatcttcat agaatttttc tttattcttt ggggtattct
42181 tctcggtgta atattcaatg aaaaataaat atcgccagtt tctatcatgt tcgtccaaat
42241 ggaatggtct agagtttata gaacacatgt tgagtgaatg gatttttagt atgttcaaaa
42301 catctaccaa agaaccaggg tcatcttgac gagtagtaaa ggtgagtagg ttaacccgta
42361 gtaatccagt gtcttctact tcattgtcgc ctgcgttctc ccttctcttc aatactaaaa
42421 atcttgttgt atttcctagc ttatcattta tcgaatgttc aatgatgtac gccttatgca
42481 attgggcagc tgtttcacta gcaatggcta aatgcagaat gttgtcgcaa tcggccgttg
42541 atgaccgaat gcattggttc actgattcag atgtggaaga acaatccaat cttataaagg
42601 tgacctgcgg aaatttttct gccatggacc ttaagtaaca ttcaacctgg ccccatactt
42661 gcggatgtga gtgtattatg acttcttcaa aatttccaag ggatgcaata ccatttggta
42721 gttggattgg gctgattaga caatgggtaa tgggtacata ttgctccgct ataacttcta
42781 tatctggtgt aattctatta gtatctgctg gagcaggtaa ggatagggct tttttgatca
42841 tcctatcacg caagagatca taggaaaaaa ctacttgtcc attggtggaa ttttccaacg
42901 gtaccactga ataatctata ctagtgtcgt tctccaattg gttaaaacat tgggggatag
42961 aggctgctgg gaggtactca acatcagatg ttgattgaaa ttgttgtaat gcagcttgat
43021 gggaatacgt acctttggga cccagaaaaa gaaccctcaa agtcttgctg gccataattg
43081 aaggatgaat gcggaaatat aatgaagttg cttttcgtac ttttttagcc tgttctttct
43141 gcgtattata ttcatctact aaaattttta ttttcatttt tcattatgaa aatacaagag
43201 tcatgctgat aactgtgtaa agaaactgta cgcttgtcgc agatgatgta gtacgtattt
43261 tatttacagg tgtcattaat atatatatat atatatatat acgtatacgg aagtaattct
43321 tcgttaattt tccatggact gtgatagcga aatcaatttc tcgacggtga atcccggaga
43381 ggccttagag aaatctctta acaactgcac tctctgttta gcaactggag tttcttcacc
43441 cattgcacca taaaaccttt gcacgtttag caataacagc tgtgcatcct gtacattcac
43501 gtttgtatcc ggttcaacat ggccattcat aaaaacaatt cccttatcct tgaccaaatc
43561 agaatggaac tgcaaggtag tatgtggcct tgcaaattcc tggtgtagtt tgtattctgc
43621 tagggaagtc atcatacaat gtgttgtttg gggtccgaca aactgccatt ggatgtagtg
43681 tagttccatt ccctgttctt cgttcggttt tgcatcctca gattgaactt gtctaggaag
43741 tggcaacacg aatatagggt tattcctggc atttgccatc atcttatcat aaacggagac
43801 aggaatcaca gcgcataatg tattatcttt ttgtgcccat cttgctctcc aaagaaactc
43861 tacttcctgt ttcgataagt ccttcagttt tccaacatcc aaaaaagagt ccaatgtttt
43921 gaagggaact ttaggagcac ttggatcgag aggacttctt gatttcgtca tcaaatgctt
43981 ggagttgtta ttttccattt gagttttttg ttggtaatcc tctagttctt tcagggggtc
44041 gattttatta aattcccgct tcttagactc tatagtctct ttcaaatgat ttttcaactc
44101 ttctatgctg ttaaaacctt gtttttgagc ctcttccaaa agtttctttc tatacttctg
44161 ctctgggctg gaagaataaa aacgaaaaac aggaactgtt ccaattgcct tgttaaaaat
44221 gggcgacagc tgattagaaa tatggattct agtgccgatt tttctggtta gtctccacat
44281 agttattctt aaatctcttt tgttctctat tttcaagtct tgataagttc ttcacatcct
44341 tcgattacgg cgtcaaaata agcgttattt ccattcgggt gagttgaacc attgataaca
44401 acatggttta acgatacttt gaaaggttta ggcggagcca accataatgg atgaatcggt
44461 ggatcctgtg gagctgcttc tacgactact gatacggcac aaacctcatc tgaaaccata
44521 tgcctacaga caagatagct ggcaaagggt gctcgatgag tacaacagac agactgggtc
44581 aagatataga caatcaagga cgttaaaaac caaatttcgt cgactgaagg acctcttcag
44641 cgcagatcga gcccaattct ctccttccca gttgaagctg atgggagcac tcttggacga
44701 agcaccagaa catccaagac caagaactaa attcggaaat gaatcatctt catccttatc
44761 atcatcttct ttcattaaaa gtcatccggg gcctgatccg tttcaacaat tatcatccgc
44821 tgaacatccg aataaccaca gctccgacga tgagcattca ggctcacaac cgctgcccct
44881 ggattcaata acgattggaa ttccgcctac tcttcacaca atccccatga ttctgtctaa
44941 ggataacgac gtcgggaaag tcatcaaaag ccctaagata aacaagggta caaataggtt
45001 cagcgagaca gtactgcctc cacaaatggc tgctgagcaa tcgtggtcgg actctaatat
45061 ggaattggaa atatgtctag attatcttca caacgaactc gaggtgataa agaaaaggca
45121 agaagatttt gagtgtaaag ttttaaacaa gctcaacata attgaggctc tcctttcaca
45181 gatgagacca cccagccaag gagataaaat ataaaaactt ctattagata tgcttgattc
45241 atgtccatat gtatctattt atacaaacat tacgtaatat acacagatta tacatgaaag
45301 gtgctcttca tatttggctt cttgcttcca ctagcctatc ccaaccagga gagtcatccc
45361 atctgccttt gcctttactc attagagctt tgatagtaga tctacatttg tatttccagt
45421 ctttgcaaac cagactgcct ggcccatatt taccttccat ttcaccaagt gattcatagg
45481 cagccaccaa atcttcacaa gcatccactg tatcattcca aaccttttct tcaacttcta
45541 aatcaggatt gtgagaaatg gccctataag ccttctcgtg gcattctagg gcggcccatg
45601 gtctcttcct ccaaagttct actcttgcga ccagtcgcca acatcttgca ctggttgtaa
45661 ttacctgagg taaagtgtta cagataaact cagtacagct cttttgaaaa taagataatt
45721 gctgcggctc ctctggatat tcactagtca ctaatagttc tactagtttt tcaataattg
45781 gtaagtcgat ggaaccttcg ccagatttgt ccctcctaat actgactaat tgtttacatg
45841 cagttaagac atcctcccac tcattcaact taacagcaac aagcatgtaa ttctcccaaa
45901 ttttccagtt cttttgagcg tcacatgaaa tggctctttt caaacaacta taagcttctt
45961 tcaatttatc cattttcgta tatgcagcgc tcaaatttga ccatgaaaga gcatgataag
46021 ggtctaatga aacacatctg gtaaatgcct ccgcagctat ctgcatttta ccacattgta
46081 atccaacgca accataaaaa taccacgttt caaagcttaa tgggtattgc cttaacgagt
46141 catttaaatg tttcaaggta gcagagtaat ttggttgtgc tccagacttt ggaggaggat
46201 taaagtaata ctttgcaagg gaattttttg cgttgacgta ttttccaatc tcccaacttt
46261 tttcccatag ggatggatcc tgttttatat cacccaaaat ggagtaagcc ctggcatccg
46321 aatcattttc atttattctt tgaagaagga tttcttctgc ctttttttca tctccaacag
46381 cggcataaca taatgcagtc tcgcatgcca taccaagtct ttcataaatt tccacagcgg
46441 acttcaaaat acccagcgac atatattttt cagctaaggt ggcatccaat tgccacctag
46501 ggatgaacgg cagctggtgg atgtatgaca gcctgctagc aacattgatt tcgcttgaac
46561 ttggaaccaa tttactctta atcttcaaat ccaattcttc tacgagggat tgcatttgta
46621 aaagtcctct ttcaatagtt ttagcctttg ttgtctcaat aattgacctt tcccataatg
46681 atcgggcgaa aatagaccaa tttttgtcac cgttttgata taatattcta gaaagcaaag
46741 cagtaagttc ttcttccaca agaggatcct tggccggagt tgtgttcttt atggtgtaaa
46801 gacgtaacag caactggatg ttgtcgtaat cagatagggt aggttgatcg ttagggttca
46861 aatccagcaa caactttgga atattttctt gacgtagtgc caatggcaat agtttatctt
46921 cttcataacc ttcatttagg tctacctttt gtcttttact ataaatttgc tcgtctagag
46981 gttcatcagc aatggactca aaatgaggct tctccaataa tagatcggac tctaaagcaa
47041 atgtttctgg tgtagcagat gtcgttctca aagcaaaatt ttgaaatgtg aaggatttgg
47101 caagaatgat caaaccggca tgagcctttt gctgatattt agttctagta gcgcgtgcac
47161 ccgtcattac aaattcaaaa tttgttatct ttttcgctct ggtcaaggat ggcaggcaca
47221 aatgttctgt gttgatggcc aatgaacatt tgacattctc tagatagtac attgcacaaa
47281 gttctctttt gaaatcttcg tgaatactct ccggtaattc cttagttatc gcatatgcaa
47341 ggtcagcaga ctgatatatt gcagatgcaa cactagcttg gaacccagaa ggttctggaa
47401 tcagtgacaa ttgcgtcaaa agagctcttg cccaccacca ataagctaca gctaataatc
47461 caggagtaga ctcagcagag ataataggta gcggaatttc ttgatccggg gtaacatcaa
47521 ataagctttt ttggccggtt atcctttcaa gtaataatag tgataaaacc aaatacaatg
47581 gatcatccat aaattcgtag gcaggctggc ccataatggc taatgagcgg gaaagggctg
47641 tattaactgc tcctatttca attccagttt tgccaaacaa acctgagatt gctttcaacc
47701 tagctgctgg gccggtgtag ttattttgaa taaaggtctg taagagggca atagccaaaa
47761 atagcatctc attttcttgg cccattttga aaacctcaac gttaagaaag tcatttagag
47821 cagcaataac actagatgtg gatatttctc ccgaaatact aatttttccc ttaaatttgt
47881 ccacaaattg ctgtactagc tggtatgatt caccactgat gatatgttca gcctttttca
47941 catatgtctg gtcgaaagaa ccacttttca gagattctac ttctgcagac agcaataatt
48001 ttgcatgcaa taacgtctcc ataattttgc aaccactagt ttactttttg cctggtctga
48061 tagcttcttt ttagcaattc ctttggcctc gatgagcttc cattttcaat tttcatcttt
48121 tttttcacga tgcgaagttt cttagataat tatcgccata tacgaaacgc gttaggaaac
48181 gcgttctttc ctttataata agcaatatta tatcaactta aggtggaagt aatgtggcaa
48241 aatcgatagc gactatctag aacaggctag tttaagcata tacataatgg caagtatgta
48301 ttagtgctag gaattggagg atttgctctt ttctgcatca ttttttttat ttttattggc
48361 gaatgttaaa attactaaca atggatggga ttccaataca gcctatcaac catataacga
48421 atattcatca gtaacgggcg gtggctttga gaactctgag tcccgcccag gtagtgggga
48481 gtcggaaact aacactagag ttaacacctt gacacctgtg acgatcaaac aaattctaga
48541 gtccaaacag gatattcagg acggcccctt cgtttcgcat aaccaagaac ttcatcacgt
48601 ttgttttgta ggtgtggtga gaaacattac agaccatact gcaaatattt ttttaactat
48661 tgaggatgga actggtcaaa tagaagtgag aaaatggagc gaagatgcaa atgacttggc
48721 tgccggtaac gatgactctt ctggtaaagg ttatggttcg caagtcgccc aacaatttga
48781 aattggcggt tacgtaaaag tttttggtgc tttgaaagag tttggtggta agaaaaatat
48841 acagtatgcg gtgattaagc ccatagattc attcaatgaa gtgttgacgc atcacttgga
48901 agtcatcaaa tgtcattcca tagccagtgg aatgatgaaa caacctttgg agagtgcatc
48961 caacaacaat gggcaatcat tatttgtcaa ggatgataac gatacatctt ccggctccag
49021 tccgttacaa agaattctag aattttgtaa gaagcaatgt gagggcaaag acgctaattc
49081 attcgctgtt cccattccat tgatctcgca atccttgaat ttggatgaaa ctaccgtcag
49141 aaactgctgt acgaccttga ctgaccaggg ttttatctac ccaacttttg atgacaataa
49201 cttctttgcc ctatgaaaat atatagatta tttttttagc atttcttagt attcgtttgt
49261 gtatttctac taggtaagta ccaaaatttg ccggaaatag agtggaaaat ggaacccgtt
49321 ccaagaaggg gtaagatgca tgaatattaa gttggttgca taaatatgct atataaagtc
49381 cactacaaaa agtcatttat ttttgcccgt aagaataaag aacgaatccg tccttatctc
49441 tgacttcaat gggaacattt acacgcagta cgggcttcaa taatagttcc cagtcgtatc
49501 tggttctagg tgtacataat gaaaaatgtc tcagcattct tattttgaca gctttgaatt
49561 ttgacaaatt tctcaggaaa caccagaggt taatatttgg aatatcttta aaattctctg
49621 gatcttggaa atcattgaaa aaattttcca atgtcacatt ttgtaagaac tcctccacat
49681 ctaaatctct atattcgatg gttcggttct tcaatttgat taaactatct cttaggcaac
49741 gccttacaga gttgttccaa tagtaagtgt ggtgaatgtc tgattcaggg ctcattactg
49801 tacttaaatt tggaactgca ttagcatttg gtatgttatc tcttatggaa ttattttcgt
49861 aaccgattaa tgtttcttga tcgttctcgt cgccaacatc ctcatctgtc tcatcaacac
49921 tagtaattgt tcttgctaga tgttcccaaa acgatagagg ggataaagga tacacattgg
49981 taaaggggat attgattacg ttaatagaaa tatttttact tggaagtctc tcccaaagta
50041 agcggtaata atggtagaaa gaatgaaatt cagggattct ttgtcgttga aaattttgta
50101 gctgtgccgc agttaacatg gcgggctttt tgttattgtc tggtgatggg ttatttgaaa
50161 catcatttcc tgtagttcta gaaatatagt tcagatttaa ggacaataca actgaagatg
50221 tcggcggagg agtaattatc ttcgaatctg atggcgcttc aaataatgtt tctgtcatgg
50281 aattgcagtc atcaaaatca tcttctgtat ccaaacttcg ctgttggaaa taatatgatt
50341 cgccgactac ctgttcgtta gtgaaacatt tgctattaca atcaattgtt agattggata
50401 acgatgggaa acaactgcat aacaataagt cgaatttact gttaatcttc agtaaggata
50461 gatgtttgac cattttaaag taagagtgaa acaaacgtaa tattccattt ccaggaacta
50521 catcacatga atctaaagta agtgcagtga taggagactg taaactgtac agttcattat
50581 cttcgttctt tagaaatagt ggtaagaatt ccattggagt atctagcgat tcggtgtcta
50641 tcgttacatt ttctagttta agttcattaa ttatgccgaa acagcagaat aaactcggtc
50701 ttagtacgag cttttggtga tggcgttgac gattaaaggt tctttgtctt ttattattag
50761 ctttgatttc cagtattttc aaccttggca gagaataata cttggattcg tattctttga
50821 caaatttttt ggatagttgg aaagtcctca aatcttcgtt tgtgatggat tgctggccct
50881 tgattatttt cttgaaaaaa tctctagatc catcgttgaa tacagagtac cataaaggaa
50941 ttttaaaatt cggttccaca tcactcagaa tcactctggt caggttcggt agatagtcta
51001 taatatcaag cattagctca atataagtat aatggaagta gttgctttcc aatttatcaa
51061 gcagtttgat tcgttctgaa gttatgatgg gagtctcatc gtttagtctg atgttattca
51121 gtttttttac gtctttatca tacgaatcga gtttataaga tccagcaata atagaatctt
51181 ggccactctt attatagaac ttactgtatt ttaacaacga gtcttgggac tgaggatttt
51241 tgaattcgat ggatcttacg aggaaccttg cattttgtga tctagattgt gtgctacaat
51301 caccgctgtg tgtgacaatg ttcgacgtgt ggaactcgga gtgtatcaaa gcattgaact
51361 ttaacaacga aagttttgag tccaaaataa cgttttggaa aaggaactca ttcgtaatca
51421 aattgtagaa cctcgaattg acttggcata gtgttactaa tgtattgaag tccaaagttc
51481 gcagtattaa cagtagaact tttgttggca aacacatgag ggacgattta tcgttgaagc
51541 gtagtgatct cgatttgata tcatggctcg tactatgtag aaggcttttg gcatcagcac
51601 agccctcttc ctcttcttct tcctccttcg cagcactgga gaccagcgag aaatattttg
51661 atctaccaaa caattgcaac cgtttcatga ttcggttggt ttgaacgttt gaaaatgcgg
51721 ttcaactttt catatctagc agtggctcat ctttatgtac tctagtccta aatcttctgc
51781 tggttatcgc aaaaaaatat gtgatgtgcg ggtttttggc agtaatcatg actcagtctc
51841 tggaaaaacg tgctatttaa cggttatata tctatctatg tacatgcctg tgcatgagct
51901 cttcattcat ttctgggaag ggtgagggag ctgggatgca ttttctgagt tgttcttggc
51961 atattttccc aggacgtcct ttagcgaatc tgggatgtct tcaaactcca agtcgcccac
52021 gtcttggcta acttgttctc cgttagcttt cattaactgt tccacggtaa catgatgatc
52081 atggaatatt ttcagatggt ctgctatcaa atgtctcact ttgcagtgcg gacaagagat
52141 caagacagta cctttctcgt acgcctgctt ggacattgtg tgtgaagatc gggtgttaca
52201 tttcttgcag gtgaaagcta tcatcatctt aggcttgtct accttaaaag accccaaatg
52261 aaccttctta tcgtcctttt tcacttcatt atgtgcgatg atattggtat gcaacgctgc
52321 tgcgggtaga gtacggcaca cgttgtagcg tacgcgaggc gcccaacatc tggcaaagta
52381 cctggtaatt ggtattttac tttgcagtag tgttctagtc ctcggaatca tgttcagtct
52441 cttgatattc cagttgcacc ggtgctgctt tagtatcgct gatcccttga agccaacatg
52501 acgctctttc acctttcctc tcataatttt gatatcacgc gaaaatgcaa gaaaaaaaaa
52561 ttacaattat gaagtgcaga aggaaccaaa aatatcatcg aaagaaggag tacgtagagc
52621 gttactattt tcaatcagtg ttcccattgt gcatacaaga aatgtctcaa ccccagatgt
52681 cccctgaaaa agagcaagaa ttggcctcca agattttgca tagagctgag ttggctcaga
52741 tgacgcgtca attaaagctt ggtttaagta atgtcccatc aacaaaacga aaacaggact
52801 ctacaacaaa gaaaagaagc ggagaggatg ccgaagatgt tgatgaggac cacaaaactc
52861 ttttggaagc catatcgcct gcgaaaaagc ctctccacga tgatacaaat aaaatgactg
52921 ttatatcgcc cgtaaaattt gtagagaagc caaatactcc cccaagttca cgccaacgaa
52981 aagccgaaga ccgctcacag cagatcaagc ctaggaagga ggacactcca tctactccga
53041 gggcttctgc tacacctata atcttaccac acgcttcgtc acactaccag cgcccccatg
53101 ataagaattt catgacgcca aaacgtaata ataacaacag cagtaaccat agcaataaca
53161 ataataatat caagaagaag gcagcaggct ctaaggatgc tccacaggac agcgacaaca
53221 ctgcgggcgc tgatctctta atgtatttag ccacaagtcc atataataag tcatcacatc
53281 atggaacacc gatggccgta aggatgccca ctactccacg ctcttatcat tacgcgtcgc
53341 aattgagttt gaacggtaat acagcaagca catcaaacga tgcagtaaga ttctctcata
53401 tcaaaccttc agcgtcttct ccgcagtcca ctttcaaatc taatctgtta ccgaattttc
53461 cggacgaatc tctcatggat tctccatcac tatacttgag caataataac ggtagtgtcc
53521 aggcgacact atcgccacag cagagaagaa agcccaccac aaacacattg catccaccta
53581 gtaacgtacc taccacgcct tcaagagaat tgaacggtac caattttaac ttactcagga
53641 cgcccaactt caacatggga gactatctgc ataatctttt cagcccttca ccaagggtcc
53701 ccgcccagca gggagcgtca aacacgtcag cttcaattcc ttctgttcca gcgatggtgc
53761 ccggatcatc ttccaacact tctgcgatag caacagctgc tatatcaagc cacaccacaa
53821 acaattttct agatatgaac gcaaacggga tcccgctcat tgtaggaccc ggcaccgacc
53881 gtataggcga aggggagtcc attgatgaca aactcactga ttgatcgttg acggccatat
53941 cagttgatga ttccatactt cctgaaatgg accactcaaa gggacaaaaa tgacaaatgt
54001 tgaaattata aaattacata ttaatacgta aaatgacatt cttttttagg gaaattcgga
54061 gatagattat cactatgtaa gcttatgtat cgtaatatac agggccgata tttcacctag
54121 tttacttttt ctggtggcct ttatgtttat gactgtgccc cctcttgtgt ttgcttttag
54181 aggctttctc tacaggtatc agtatggtgt cctcatcctt ctcccctgcc tctgcttcga
54241 ctggagctaa cccattttcg ttcttaaaag ttttcttcct ccactctctt aatcttcttg
54301 ccttcatcac tttcctttta tccttcgctc ttagttcctt ggaacgataa ggtgcaaatt
54361 tcttcaaacc aataaattca tttaaatcag tatcatcggc ggcgaaaatc tctcttgcgg
54421 tcaaaccgaa actctcagga gaaacttcac ggtaacgaaa cttcaaatct tgctcctctt
54481 ttgtacggct tctactcttt ctttcttctt cttctttttc aacctcctct attagtgcta
54541 gtttgttttg ttccaaagca ttttccacta attcatttac ctttctcttt tctttcttct
54601 tttgcagttt ctcttctttc ttgctcttct ttctttttgg accttcttcc tcgtcttctt
54661 ctttttgttc tttttccact tcaccttctt ctgtttggtc atcaccatcg gcgtctgcat
54721 aaaagtcacc cattatttcg tcatcctcgt tccaggtagg ctttccctct tgttgataaa
54781 attcttcatt aaataattca gctaccacgt tatcccactc ttcttctttg aaatcgttct
54841 tcaatagggt gtcagtgatt tttttcacca tgtcggcatt aatttcagca ccatattcct
54901 ttgttagttg ctctaaaatg tcagtcaatt tattcaattt tttagtcttc tttttctgaa
54961 gagctgtctc cttctctgct tttatttgct ctttaatttt tcttttttcc tctctttttc
55021 ttctgcgtga agagtcatcg gatcttctta gtgtagcttg actacgtgca taagatataa
55081 tttcagctgc gtttgggtcc tcgtacctaa aattgtaggc attctcaaat ttttctgcag
55141 catcttcaaa ttcttcatcg tcctcttcat tattgttgag gtcaagagaa atcaccttgt
55201 cccccttctt aggaatccag gcctgttgat tcacaaattc ttccaagaaa ttttcttcat
55261 ttacggttgg atccggtaaa ttttttcctt ccttcttcgt agaaggttcc tttttcttca
55321 aaaacccatc gtcttcatct ccgctagact cttcattttc ttcatcgcta aaggcactct
55381 tgatttcatt taaaagctga gttttctctt cacgttgttg cgagacgaaa gattgctttc
55441 cgtcaacagt tgcatgttcg tattcttcgt catcctcctt taaggcatca ccagaaagta
55501 tgttcatacg gtgataatct tttaggtaaa taggtttatg cttcccctca cgattggcca
55561 gtttggcagc agcagattcg ggatcctcga agaatttgac tttaggatct agtagtttgt
55621 ccgtcttatt gtttttgatg gcatctagca cttgattaat accgttttcc acttcatcag
55681 taatcaattc accgtaatca tcttcctcct cttcttcctc ttcgtcttct tcctcatctt
55741 cactaggaac gtacgatttg cttgcttcga ttgcaggctt aactgtcgtc gcagaggttt
55801 cagaagtttt tatggtagca gtatccgttg caggtacggc cgcttctttt tttgcttgtt
55861 ctctagctct tttagcggca gacttttttc ttggcattga atttagggta tatcacactg
55921 ttgttgaaaa ctatgagcat tttgctttct gaagaaatgg ttctgttaac tagatgagat
55981 gagattgata tatttgaaaa attttaaccg atgaccttgc ggctcctccg ggtaatactt
56041 ttttctcaca taaatatcaa aaaataacga cggtatttca ataatacttt tatataagta
56101 atgataacat gcgaggcaat ttattacaag ccacgtaggc ctaattaaaa ttataaacta
56161 acactaaagt aataataata tttcagatta ataaaagaac aggaaatagg aaagagataa
56221 aaaaaaatta ggaacataaa ataaaaaata aagaagaaat tgaaggagtg actggataaa
56281 agaagtgtat gataatatca aatggaaatt tgaatatatt ttattccaaa aaattttttt
56341 tcttttccaa gtgaaatata aacagcggat caaaggtgaa aaaaatcata gtattttgtt
56401 cattaaattt tccgagggga aagagaacaa attaatagaa aattattatt cagcaacttt
56461 cgtaggttta attttatcag caaattcacc cagaatttgt aactcaaaat cattaaaatc
56521 aaacaaattt ggtagcttga ttggttcagt gaaacctctt ggtaagaaag tgtcatcatt
56581 ccttaattca ttaaagaact gatgggcaag gattcttctt ggagacagtc tttgttgtgg
56641 ttcgtagacc aatattttca tcaaaagatc gataccatct ggaccggaat ggccaaaata
56701 cttctcaaac ctctgttgcg aagagcccga gaacagtggt ttggaaaata gagggccatc
56761 gtaggccgga ttcgaaaaga aaatgaatct tttatcggga ggacctaaca atttagcaat
56821 ttcccttagc tgtagaaggg gttcttgacc ttgaaatatg gctttgccga taagcatctc
56881 gcccatgaca caaccaagcc cccatatatc gatctgggtg gtatattggg tacaaccaat
56941 gatcaattca ggcgctctat aaaatcttga acagatgtaa ctaattgaag gctggttatg
57001 ttccaatttt ttggcagacc caaaatcgca gattttcaag acaccggttt ccgggtctac
57061 aagaacattg gatggtttga tatcacgatg acaaacgcca agaccgtgta aataaagcat
57121 cccgcgggca atctgataag tgtatagcct gatatgtttt aatggcattt ctagcttgtt
57181 tgtcacataa cgattaatct cgatttgtag agtttctggt aagcattcca tggcaaggtg
57241 ttgataaact ttattatctt gcggggacaa atgagtaaag aaatactgca atttaacgat
57301 atttggatgg tcggcaatcc tcagaatctg taattccctg gacttgtact cggtatgagc
57361 agggactttt ttaattgcaa aggggcccaa ccagtttttc ttatcctggg ttaaatatgc
57421 ttgtacaaca gtcccaaagg cacctctacc gattttcctg tactctttca ccagcatccg
57481 cctcgtgttg ttcgatttat tcgaggttac atcgtctgca atgaattcag atcccctttg
57541 cagaggaaca ccattctgct cttccgtaga catatgtact agaatgtgat ggagtggggg
57601 tttcggaaaa taaaaagaaa attgaaagat gaagcaaaga actctgtagt cttgggctta
57661 actcctatca ataaacacgt tacgggcctg cccacactac taacacgaca caatggcact
57721 cacttgcgaa atctatgtcg ttttcccttg gaggttacgc ctgccctctt ccgcatatga
57781 aggtcgcttt tttcagtgtt gtttgtgggt cactgaactg tcattacata cgaactgagt
57841 ggaagcaaga atgctgcttt cgaaagccac tacagctacg tgtgatcata taattcctgc
57901 ataatatggc tgcatgcttt ttaatgatag cttcaattat gatgataatc actgagctac
57961 tagtattcca ttattcagcc taagattgga actttctata gcagcggaga gtgtttgttt
58021 cgtacttcgt gactgtttgg cataataacg atgaattggg aaagagggaa gacaaaatga
58081 gagtaaatca ggtggaaagc agtggttctt ctgaaaagaa aaagtgacag tgtgaactgt
58141 tatagttacg tgtgatgctg ttacaacctg tttggaaagg ctgccgatgg acgcagtttg
58201 tcaggcctat cagaagatgg aattctaccg gcacgaatag aggagttcct ttttcattta
58261 aggatatttc aaatcaggag gatatcacga atatctcgta tccttcgtcc tctgactcag
58321 ttttgacaaa gtcaaatggt agtagtgagg tttacaagcc caaagaggaa gtagttaagt
58381 acattctaca tggcaagttt actaaaaata acacgcattt gacattttca agcgttgtgg
58441 aggacaagaa ctttcataag aataagggac ttacgtataa tgatacaatg ctgtactatt
58501 tgaacttacc ccagaaagtg aagatttcgc tatctacagg ttgtttaggg tttaggaagg
58561 cagcaagagg ggagtatgaa gctgcatttc aaaccagtgg tagaatgttt gaattgatta
58621 aggaaaagaa catgctgaac aaagatatcg aagtggtgat ggacgacttt gggaagggca
58681 gagctgcttt tatttccgct cttgttggta aggaaggggc cagtgtggtg aaaaaggttg
58741 tgaagatcag cgatgccacc aaattgaagt ttggtggtgt aagatcacca aagatgagaa
58801 gactatgatc agctcccact atgtatgaat tataaactat gtaaaagaag aagaaatata
58861 tatatattcg tgtaaataat tcgatttttc ccttttttta attgtcgtcg ttagagttgg
58921 ccaaaatcct taaaatagac aaaaacaaat tgacgatgtc caggtaaagc atcatggcgc
58981 atctaacttc ttcatcagga tacactttcc taaaaatcag ttgcgtatcg atgaaaagat
59041 acgcggtaaa taaaatggca ccaagccagc cgtaaagcag attaaacttg gaagagtggg
59101 tattccagcc gaaaagcaag gccgtgagac ccattccgat cataatccat agaccccagt
59161 ttaaccaata gtatattgac gttgcggaat tcagcacgtt ctcgaatctc tctgatagtg
59221 cggtcaagga aacgccgact acgacgatgg tggtgatcag cagagccgaa agtactgtat
59281 ccttatcgta cgctaaggtt accagcgaca gacagtaagc ctcggaaaga gtgaaaatgg
59341 agagcagcgt gagcttttgc ttgtacgagg acaagacgta ccaaggcaga cgcctttgct
59401 cttgtgccgg ctcttcgctg ctgcccgtga gcaacggttc gggaacactg gcctcgtagt
59461 cttcgggacg aggacttact gccagccaaa tgcacgatac tagcgatacc accatgcaga
59521 tgtagaagag ggcgatatgc gacatgataa agttctgcaa agaagtggaa acgctagccc
59581 agtagcagaa cgacaaactg gccagtaact ggcatgacag cagagagtaa accttgtgca
59641 taaaccgctg gcgaatgatg ggttcgcacg agataaccac cgtggaatat ttaaagtctt
59701 ccgggatgaa agcgtttcca tcctggctgc tcgcaggctg gccgtaaaga tgtgagcttt
59761 gctcttcgta aggaggtgga ggacctgaca tattaacttg attctatatc cttttatttg
59821 ctgttgctct tgaaatattg tcaagagtaa gatgagtgtt atagctgatt cttttcttta
59881 tcccggaaag atccttatta tagcctcaaa aggggagcgg ccgggtaccc tggttgcgtt
59941 gccgccccaa tctgccatag gcccacccat aagagtttag aaatgaatta ttcctgggcc
60001 aatgctgcga tcacgaaaat tatcaacatc ttgataaatt aatagcaagt tggactaact
60061 tacaggtttt ctcgtgaggg aagtggaaga gaaagaagaa aggagcgtat gcaactgccc
60121 ttggcagccg cccatcgtca ctcatggccg ttacgcgccg cggccgaaac acgccaaatg
60181 ctatgtacat aacggaaatg ctaatacgta acaatataat aatataaagc tttcataagt
60241 cttggcactg gcacttgcat cagcatctcg tatattagat acatcatcaa gtccatatgt
60301 cccagagaaa gcgatactca ttgaacgtcg tcacgtcccc gtcgataccg tcaccgacac
60361 ccagtgcacc gatacggact aacgaatcca attgggaagc tgcttcgcca gcgagtgctg
60421 catcttcatt tctcccgaat gttcatcatg gtggcacggt tttgaatcct gggttgggca
60481 taatgaggtc accttcgttg aacaagtctg gtgcgtttgg ccggtccggc agcagtggtt
60541 ccagtacagt aatagaaccg tccaacataa agttgctgct aattggagat gcaaacgtag
60601 ggaagacagc tatgattttg agctattgcc gggaactgtt gacacgagcg gaaatgtcac
60661 gatcggcgcg actgaggcac cagcagcagc aacagcataa agacttagga ttgaagaaaa
60721 ctgtggtgaa ccatagatta agcatgaaag agaaaagaaa acggtacagc tctaacgatt
60781 ttgaaaagga gttcaaagat attaatcatt ttgcagacga aacaagcgat ttcggaaacc
60841 cgaacatcgg tgatgataac aaccacgaaa tggcggatcc taatgagatt gtcatcgaaa
60901 ccagaagtac tatcggaata gacatcaaga cgaacttggt caacatagat aaccggtttt
60961 ttaatgtcat actgtgggac actgcgggac aagaacggta ccaaaacgca atcattccat
61021 cactgtacaa gaagactaat gcggtgatat taacttacga tataacaaat gcgaagtcct
61081 tccaaagctg tatggagcgg tggatagttc aggcgttgga aaacttttct tcccaggatt
61141 tgttaaaagc aagatttttt ctggtgggta acaagattga cctttataag gaaaggcagg
61201 taacccatta tgatgtggtg caaatggttc aggaaatgca actgaaacat ggtattaaaa
61261 tttcgggaaa ctttgaagta agctgtaaat gggtcaacgt ggtggagaga accatgaata
61321 tgataatact agacctggtt gagaacggat gtttcgaaaa caatgatcct tgtgtgtcga
61381 ttacaacatc tgacgacgtc cagggacatg agcaagaatt ccacgataca gtagaagagc
61441 ctttcaattt cactcggcaa cgtcaacacc aacttgaaaa aaataacaca gtggatatta
61501 caaaacctaa tgacgacatt gcaaataatc aatcaatttg ttgcgtttag tcttcgacaa
61561 attatacaac aagattcgca ggcagccatt gtccaatacg ccaatgtcat tatatgtacc
61621 aatatagacg cattatacaa tcctacaatt tatatcattg taaaattatt tactaccact
61681 tattcttcaa tggtgttttt aatgttttgt agaggaaaac ttaaaagttg tcatttttat
61741 tcagatcgca atccatggtt tgacacattc tatcttaaaa aaacaaaatc tatttatttt
61801 ggtttcggct atattgatga tgatgaatgt acatataaaa tggcaaaatt taaataaata
61861 aattatttaa aatcaatttt gtttgagtta aacgataata ctatagtata atgataatat
61921 taataaaaat cttagctttt tatttttaac aactcgctta ttcgtcttct tccaaagttt
61981 gagcggcaat acgatccaaa tctctttgac cgttttcaga gattcttcta ccaccctttg
62041 gagagatttc gacaataccg attttttcca aagcttgcaa gacctttctg ttgatagaac
62101 cggaagcatc aatgtgcttg tatggtctga cacctctgct cttggcacca ccgtacaatt
62161 tgttcaactt accaacaccg acttgctttc tcatgtaaat gtgtctagca acggaggcag
62221 cacgcttgta gaaccaacct tcagcgtctt gtggtggcat ttcattacca gaagaggtct
62281 tgacaatgtc aacgtaacct gggacttcta atttaccttg tctttgcaag aaagaagcgt
62341 aagcattgat gaaatcttga gctgcaacgt ctctaattga aaaaatgcac aattgaaatg
62401 cttttgttag taaaaagttt tctcgtaaaa atagaatatg gaatgctcag tgaaatgttt
62461 attgagacaa cttcttggtg cggcagtatc gtggtctcgg gttgttgctt aaattaacgg
62521 cataaaaatc gcttttcatt gcttttgcat taccacggtt acagatttcc ttccaactta
62581 aacgtcttgg ttcaggttct cctatttcat tagaaaacat cccacctagt taaaacctcc
62641 tatcaatcaa ttccaataaa taaatgatta cctcttcgtc tgagaacttc attttgtata
62701 gttggctcaa aatattctct ccacaattac agcaattata tcataatagt ttaactcatt
62761 cgttcggtaa atgcacagta aagatgaact tcaatttatc aggtaatggg aaattctgca
62821 ctaaatcctt tttctcaatc ccatatgttt tcatctcgtt gttttccacc taatatccat
62881 tcattctcta aatactcatt caatgagtga aagttatacg tacctaacgg aaacacctgc
62941 catctttatt atctttggtt ctataccttt gttgtcaata ttcacaaaaa tcccacttta
63001 aaatttcatt agtccatttt aacgattgta tcttcactaa tgttcgctta ttgaaatggg
63061 cacaccaacc gcgttacggg tggctcccag ggagccgtaa actggagatc tcaatacagt
63121 agaaagaaca gcaatgtgca aaacctcacc aaacaccagg gcttgtcact agagctccgt
63181 cctgctgggc tcaaacgcgc ctaatttatt cagggagaac ggacggacgt agacgcgatt
63241 tttttgtcaa agcacaaaaa gctgacatca ggaagaaaat caatagtgca ccaaaggtat
63301 atggtgtggg ttgctaaaat gttcggatgt aaagtagtat tgaaaaaaaa tgggaaaagt
63361 gtgtgaatga tagtttgtag gtttatgcat agggcggaat agctgacttg atactgaact
63421 gataggttta gattatgaag ttattataca tgtatatatt gtagtcagtc atatggtatg
63481 gaaaaatccc tctttcccaa cctaatatac actgaaacaa ggaaaaagga acaaagaaga
63541 aaaattgtaa ggtttcaaac catactagat tacaccttga aacccttaga tcttcttcta
63601 cctctagctc tttcgaactt tctaccggtg gacaagattc ttggagcctt acccttgtgt
63661 ggacccatac cgaagtgtct gaccgcttct ctggagtttc ttggacctct caagatcaaa
63721 gtgttttgac ccttaggagc tctgacagct aattgatcta aagtgataca ttcaccgcca
63781 gccttaacga tcttggctct ggcaccagca gtgaatctca aagcagcaac agtggtcttt
63841 gggaattcga agatcctggc atcgtcagta acggtaccaa caacgacaac agtcttgttg
63901 gcagcacctt cttgcttcaa agctctagca attctggaga ctgaaacagg tggtctgttg
63961 atcttagaca agaacaaagc cttcaaaaca accttgttga atggagcatc agtacgacct
64021 gtgattaaga caagaaaaac aaaagttttt acgttatgtt agtaaaggga taaaggattt
64081 gttggtattc tcgataggca gcttttaatt tcttccatta attgaagcca aaaagagtgc
64141 aaaacgaaaa agtaccaatt tgtttttctc tttgaagaaa aaagattctg ctcagttaat
64201 agttggtccg cacttgaagg tcgtattgta cttcctttag tactcgcaga atttccagaa
64261 aactaccgct ttctgttcta gtggaaatct ttaacacaaa agagaacaaa ttccactttt
64321 gtctaagaga tccgtcgcac gcaacgatac taagactgaa gccattagaa gatcgccggg
64381 actagaagtt aataatatca cagaatcctt ttatcctgaa gaaaattggg agggagattt
64441 caatacatac gagctaggaa agtgtatagt ttgaccaata atttcaaata gacgttatcg
64501 gattttggag cggttctatg accggatctt ttgtgttgct tggaagtgtg atcaataccc
64561 attttgtttt ttgttttctt ctaattgatt ttttctttct atttcctttg gtgaaacagg
64621 tagttttgtt caaaagaaat cattcaatgg tttaaataaa agcaagaagt atgaaaattt
64681 ttttattttt tcttcagaat tttatcatag ttgtcgtaaa ataacgaggt cgggtaacgt
64741 gtttggtgta ctgaggtctt ttttaaaaga agctccagca agaaagagtt ttgtgtgatg
64801 gctaatgaag tgtcaattgc atttggaaag cagcctgatt tcttgggcgt gaatatgaaa
64861 ttcttctttt gttattttat aatatgaagt atgaatgaaa acataaagcg cgctgagaca
64921 acgactgttc aatgtaaaat aaagaaaatc tatcgttctc aagacgtggt cccatttttt
64981 tttactttga atttcgtcag cagtgtgaca tggttagaat gtaaccccac atttgcaaag
65041 agattgttac aggagcgttc taattgtccc gtactggtac attcataagt gaaaagaaag
65101 ccatatcggg cgcgctggtt tgtgagccac agaaaccgga caaggcactt cttgaatact
65161 tcccaaggaa agcgccaagg tttacggttc tgatgggaat gcagggggga atctagtctt
65221 gaagtatcct tattccttaa aaaaaatatt ggacatcctc ttcgaaatta acaacgacgc
65281 caaaaacttg tctatgtttt caaaaccgcg cgtcacgaaa aagcaggaag cacaaagaag
65341 tgacgcgaaa atgacggtat atatagccat tagcagtcgc caaaaggtga agatcctgac
65401 acgaaatgta gcagagtcac tacattgata ctgatcttgt acttccgaat aaggcaccgc
65461 cagatcaatt ctgtctgatt ttggcgtctt ctggtatagt cttgtaatga acggtggtga
65521 ttctcgagga aaataaaatt cgtgataaat acatgcatgt gtatatataa ggcgctatat
65581 atggccttga aactttgtta ttacgcctac tccatcttta ttggtacata tatcatttaa
65641 aagagtagtc catagaaaac caactgcatt ccttccttat ccctgccttc ggctaatttt
65701 aaaccaactt tttaccttcc tttaatatca atatcaaaat acaatgaaat tctctactct
65761 ctccaccgtt gctgccattg ccgcatttgc ttccgcagat tccacctctg atggtgtcac
65821 ttacgtagat gttaccacca ccccacaaag tactacatct atggtctcca ccgtgaaaac
65881 tacttccact ccatacacta caagtaccat tgccactcta tccactaaat ctatcagtag
65941 ccaagctaac accaccaccc atgagatcag cacatacgtc ggcgctgccg ttaaaggctc
66001 cgttgcgggt atgggtgcca tcatgggtgc tgctgccttt gctttgttat aagttgcatg
66061 gacaacttaa actaggaagg atattccgct tcatttcatt aatttcacat ttttttatct
66121 acatgatatg tattttccct cagttaccag attcgctagc ttcgaagcaa ggactccttg
66181 gtcatactta ataaaggaac gtctgcttca ttctcctaaa gttcctttcg ataaggacgc
66241 agaaggcacc ttactagacc attgtataaa ctcataacta catactaatt caacgatatg
66301 ttacatttat tttcttgtgg ttaccccccg caaatttcca ggcatctcat ctcatcgcag
66361 ttaaaaaaaa aaaagttgta aaaaggtaat aaagcgatac ttgatgaaag caaacatctg
66421 taataacagt tcacaaggtt aagctggttc gtttcactag cgtatcattt tttatttttc
66481 aaataaacaa acgagggcgg agtttattgg gtcgtcatga caaggctcaa agcaaaatat
66541 tcacctacaa aaggtaaaag aaaagaagat aaacatacaa aacgtatgcg taaatcatcc
66601 ttcacaagaa cgcaaaaaat gcttgaagta tttaacgata atcgctcgca ttttaacaag
66661 tacgagagcc tcgctatcga cgttgaagac gatgacactt tcggaaacct agtcttaatg
66721 gaaaatgata aaagtgatgt cgacatacct gtaatagaag aagtcacatc aagtgaagat
66781 gaacaaaggg cagaatctag caaaagaaac aattctctcg aagataatca agattttatt
66841 gctttttcgg acagctctga agatgaaaca gaacaaataa aggaagatga tgatgaaaga
66901 agcagttttc tgttgaccga tgaacatgaa gtttctaagc ttacttcaca gcaatctctg
66961 aacactgaaa gcgcttgcaa tgtggagtat ccttggataa gaaatcattg tcattcgaaa
67021 caaaggagaa tagcagattg gctaacttca gaaatcaaag atttcgttca ttatatctct
67081 ccaagcaaga acgaaatcaa gtgcagaaat agaacgatcg ataaactacg ccgggcggtc
67141 aaggaactgt ggtcggatgc agatttgcat gtgtttggtt cttttgccac cgatttatat
67201 ttgccgggtt ctgacattga ctgtgtcgta aacagccgga atcgcgataa agaggacaga
67261 aattacattt atgaattggc gagacatttg aaaaacaaag ggctagctat aagaatggag
67321 gttattgtta aaacgcgagt gcctattatc aaattcatag agccccaatc acagttacat
67381 atcgacgttt catttgaaag aacgaacggg ttagaggctg caaaactcat cagggaatgg
67441 ctaagagact ctccagggtt acgtgaactg gtactgataa taaaacaatt tttgcattca
67501 agacgattga acaatgtgca cacaggagga ttgggaggtt tcacagtaat ctgtttggtt
67561 tattcttttt taaatatgca tccgcgaata aaatcaaacg atatcgacgt tctagataac
67621 ctgggtgttc tactgattga cttcttcgaa ctttacggaa aaaattttgg ttatgatgac
67681 gttgctataa gcatatctga tggttacgcc tcttatattc ctaaatcgtg ttggagaact
67741 ttggaacctt caaggagtaa attctcgcta gctattcaag atcctggtga tcctaacaat
67801 aatataagca gaggctcctt taatatgaag gatataaaaa aggcctttgc tggtgccttc
67861 gaactgttgg tcaataaatg ctgggaattg aattctgcta cattcaaaga ccgcgttgga
67921 aaaagtatac tcggaaacgt gatcaaatac cgtgggcaaa agagagattt caacgacgaa
67981 agagatttag tgcagaataa agccatcatt gaaaacgagc gctaccacaa gaggcgcacg
68041 aggatagttc aagaagattt atttataaac gacaccgaag acttgccagt agaggagatc
68101 tacaaacttg acgaacctgc aaagaagaaa cagaaggcaa aaaaggataa gagagaaggg
68161 gaaatcaaaa agagtgccat tccatctcca cctccggatt ttggagtgag cagaagcaaa
68221 ttgaaacgca aagtgaaaaa aactgatcag ggctctctcc tacaccaaaa caacctcagc
68281 atagatgact tgatgggact ttctgagaat gatcaagaat ccgatcaaga tcaaaaagga
68341 agagataccc cttcgggaca agatgagaaa tcaccactgg aaactaagac agtagatgct
68401 caaacgagaa gggactactg gctctctaaa ggccaggctc tttaacacaa tatagactct
68461 tatagactat ttactattta tacaagaata ccacatcgat gtccaagtga aacaataagc
68521 taatgatatc aaacgcgtgg gtattttccc tttccggaaa tatagagcca ccaaaaaagg
68581 atagtttccc gatatggaaa ttttctcgag ccggtaagat gacgaaattt ttcatctctg
68641 gcatgataga aacatagtat ggaacgtgca ggagagtctg attcgagaca cataatttga
68701 aagaaccttc tagcctgagc cttgtacatg tattagcgtt gccagttatt tgcttctgct
68761 gctaataaga tcaaaacctt aagtccttta tttcgatcga acgtactgcg ctactgaaaa
68821 ccattgcatc ttttgctatc attcattcct ggtggtttct ttggtgtaat aaatcgaaca
68881 gtgaaactga aacataaaag aaatagtgca aaatatgtct ctttcagctg cagcgaataa
68941 gatatctgac aacgatttcc aaaatatcgg accggcacct agacctccca gttcaaatag
69001 ccagggccgt acttgctata atcaaacgca acctataacc aaacttatga gtcaactgga
69061 tttaacatca gcgtcccatt taggtacaag tacctccaaa aaaaaaagcg ggtgggtgtc
69121 ctacaaagat gacggtatac tttcatttat atggcaaaag agatacctga tgctacacga
69181 ttcgtatgta gccctttaca agaacgataa acaaaatgac gatgcgatct tgaagatacc
69241 actaactagt attataagtg taagcaggac acagttgaaa caatattgtt ttgagttggt
69301 gcgctgcagt gaccgaaatt ctgtatcatc aggatcctcg tcctctttga atgtatcatc
69361 agacagtaac tccaaaaaat caatatacat tgctacaaag acagaaagcg atttgcatag
69421 ttggttagac gccatttttg ctaaatgtcc attattaagt ggtgtatctt ctccaacaaa
69481 cttcacacat aaagttcacg ttggttttga tccagaaaca ggtagttttg ttggtatgcc
69541 caccaactgg gaaaaattat taaagcactc cagaattaca ggagaagatt ggaacaataa
69601 ttctgcggct gtcattcaag tgttgcagtt ttatcaagag tataatggag ccggaaatcc
69661 cacaaatact ttagacaagc ctcaaagtgg tgaaacttcc tcctctcaaa aatcgctgcc
69721 aaacagctat aatgataaca aactcagaaa taattcagta aattcaaagt catcttcagg
69781 cgtttcttca agtatggtat cacagaggaa aacctcacaa ccaccaaata ccaaatcgcc
69841 tgtttctcta ggaagcggct cactgccacc aataaataca aaattgccca ctagtcagtc
69901 aaatattcca agacacttac aaaatgttcc caaccaacaa tatcctaaga tgagaaacgg
69961 acactcccca accaatggcc aatttcctag gggacctatg catccaaaca attctcaacg
70021 atctttgcag cagcagcagc agcagcagca gcaacaaaaa caacagcatc aacaatatcc
70081 ataccaccat caaggaccat ctccatctcc atccccatct ccgtctccat taaaccctta
70141 taggccacat cacaatatga taaatcctta ttccaaacaa cctcaatcgc cattaagttc
70201 acagtcgacc caaaaccaag caattccacg ttatgcacaa aactcaagtc ctacagccgc
70261 acactttcaa cctcaaagaa cagctccaaa gccaccaata tcagctccaa gggcgccata
70321 cccatcaaat caaaatgcta ctagtaacac acatgtacag cctgttgcac ctaagaatga
70381 ccagtcaacc ccacaaacaa tgaggcaggc cccaaagaga ccggatgcag atgtcgcaca
70441 accgggtggt gtggccaaac cgaagaagcc agcaaggcct accatgtcaa ctgcagaaat
70501 aatgagtaag ctgaagaaag tcaccgtaaa tgcggatcca tctcaatgct ttaaagtgat
70561 cgagaaggcc ggtcaaggtg caagtgggtc cgtctacctt gcagagagga cgcatattcc
70621 gacagaaagt aatatgatcg aactcataaa caatgatatt gatgagccgc acgtaggaga
70681 taaagttgct atcaagcaaa tggtcttatc taaacaacct cgtaaagaac tcatagtgaa
70741 tgaaattttg gttatgaagg attcacgtca taaaaatatc gtcaattttc tcgaggctta
70801 tttgagaaca gacgatgacc tatgggttgt gatggagttt atggaaggag gttcactaac
70861 agacattatc gagaatagtc ccaccaacga taattcacat tcaccactaa cagaacccca
70921 aattgcatat atcgtacgag aaacttgcca aggcttgaaa tttctacacg acaagcatat
70981 cattcatagg gatattaaat cagataatgt cttgctggac actagagcta gggtgaaaat
71041 taccgatttt gggttttgcg ccagattaac tgataaaaga agcaaaagag ccactatggt
71101 tgggacacct tactggatgg cacctgaagt tgtcaaacaa cgtgaatacg atgaaaagat
71161 tgacgtatgg tctttgggta tcatgaccat tgaaatgctg gagggtgaac caccatattt
71221 aaatgaagat ccactaaagg cgttgtactt aattgcaact aatggtacac caaagctcaa
71281 gcatccagaa agtttgtctt tagaaattaa acgctttcta agcgtttgcc tttgcgtaga
71341 tgttagatat agggcatcaa ccgaagagct tttacaccac ggttttttca atatggcatg
71401 tgatccaaag gatttgacat cactgttgga gtggaaggaa tgaagcacac aactatttct
71461 ataagcatat catacatact acaatcttat gtatttcttt tcttttagct atgcatacca
71521 atggcataat atataaatac gttcacctta aaagtttttt ttttaaagta aataaaaaaa
71581 gacctgcaac gatacaataa tcaatccaat gtcgtttaat attactattt atcctacgtg
71641 atttttaaaa atattcgtcc atgcttcagc ttctagtcta gtttcgtaaa tccaagtgat
71701 aattccaaaa ctttatcttg gaggccatcc attttatgag atactgggat ggttcttaaa
71761 atcaacggac ttaatgtttg taggttttca actccaattt gtttgttgcc aagggtcgaa
71821 ttttgatcta gaacacctct taaaatcacg catagcccat ttaatagagt agctagttct
71881 gttttacgca attttggtat tggtgctcgc ccaatcaagt attcatctga gatatatctt
71941 ctaagagcaa gggcaattct tgcagaaaga taaggagcag ttaactttct taatttctcg
72001 tttgtgttca acataaaatt aaccaaatct tgcaagcact ctaaagagca cttatatttt
72061 gtctgaaagc gaggatttgt ggtggatcca aatatacatg aaaaatcgaa cgaagatagt
72121 ttttgagaca attcagaaaa cgtaccacag tcttgcatca aagcattttc taattcatcg
72181 aattcatata aaaatgaaca atcccagacg gcataaatga aagtgtctaa ttgcctttca
72241 ttgaagagat caatgattct gttttccagc aatatctccc tatatttgga atactcattc
72301 aaatcgtcta tctcggttaa attatcgagc tctgggttga ttctttgtaa tgtgacaaca
72361 ataacattta taaataaatc acaaaagtta tcctttaatg gattttctgc atcttcttgg
72421 agtgatttga aaattttgtt cgacaaatca cagaagcaat tggaagcaag aacccatatg
72481 gggatttcat cactctctga ccctgtaata agcgattttc gcttgatgat ttcagccaaa
72541 tttttcaata ttcttaaaat atgctttgct ttcagtgtgg atataccaaa ttgatctatt
72601 tttgctattc tatttctcag gttagaacat gacatatagc tgattgcctc aaaagttggt
72661 aacctgttaa gtgatgcttt tggaagcttt ggtccaagtt tttttgttat tttttccctt
72721 gtatcaaaag ccaatatcga tattgtactt aactggagaa gaatcaaaat ttctgtatct
72781 ttagaatcat ttgtcataaa tatatcaagt ccagacaata tggccttttg catagaggac
72841 ggtttagttt tgtcttggac aaactcaggt aagagaggat attttatggc agaattgaat
72901 aaaagaagaa ctttttccac aaattcatct gtcatcgcat cgtatttcga tattaattgg
72961 taaagaggag gaaatccggt tattagttcg tatatacaat cgtattcagt tttgctcgat
73021 gcgtttgtgg agagatcact gtacgtaata ttgtagtcgg taaatatttc gcagcacttt
73081 ttcaatatat ctgatggaac gtcctcaata gtgatgattt ctttcagcag ggtttgataa
73141 tttaatatta cagcattctt ggtattatta gaagtggaag acaacaatct tttcaaaaaa
73201 tctaataaca ttgaccattc cttggcgcag gtagtgttgt ttttgaagtc cttaaagtgt
73261 tccggataaa gcttaattaa tccttgcaat gttacattta taaaatcagt ttcattttcg
73321 agttcttcag tggaccattc cttggtaagc agtggttcaa taacctctaa gaaaattagg
73381 tcccatgggg ggaagcaaac agaatgggag tcgatgattc tgaaaaaagt ctgcacagca
73441 ccgtttttaa cttctactct atcatcatta gtacaattga tcaaattttt caaaagatat
73501 atccataatc cgttgtaaag ttcccaatca tgagatgaac tggatgtaat gatttcaatt
73561 aatttttgat tattaatctt ttcggagaga cttctacgtt tctcatcact taaatttaat
73621 gtttcgggat tgaagcggac tctgagataa tctccaacta accagaactg actaatagaa
73681 gaaaaggaga tattaagatt tcgcttctga cttacgaaat tgacaagcgt atcaataacg
73741 aatttaatga cactcatagg taaactctgt aagaaatcat cagaaattag tttaaaaaca
73801 tcgtatgaca cttggatcat gttcttatgc ttctgaacga taccttcaaa taaagatgaa
73861 tcatctatat cctcattcac ggaaaaatca gtatcctcaa ctgtccactc gaatggtgaa
73921 ttaatgatgt tgaaaatatt ggtccaagag ttcattaaca gttcaccaaa ttcgttcaga
73981 atctctttta aagttagtag caattgaaaa agaatatctg attcaacatt gatcgtccca
74041 ttgtatattt cctgcttacc aatatccaac tgttttatcg agtttatcgt tgccatcaag
74101 ctatcgatga ctaagttttc caatgtacca aactgtttca ctttattatc ttgctcatcg
74161 gaattaccaa cctcattagt agcctttttg atgatatctg taaacactct cactgtgtat
74221 aaacgtaaag aatcgttatc catttcacgg tttgatatca atttgatcat ataggtggaa
74281 atcaaactcc aaagttcttt accatttttt ccaaagagaa attttttgca attataagtt
74341 gccagttcac caattttgtt aacaaaaaac gccttgttgt aaatgcatgg tataatttca
74401 tcttttgcat ctaaaggatg atagccaatg tcattattca ggttgaggtt cgtttgttct
74461 aaagtgaggg tattttttga gtccaaaatt aatctggtta ataccaaatg aaaagttgag
74521 caagaatagc tgcttgtact ttcaaaaaat ttcgttagag agctttcaat agatgtaacg
74581 tctgatttag tcagtattgg aggtggtgga atatcttcag agtaaaagct ctctttgaaa
74641 tctgctgatg gaccatatat gtagtaagtt atccattgcc aggttaaaaa agtgtacctc
74701 cagctttctg aatcgaaaat aggacctagt gatattgata atgatattaa tgcccttagt
74761 aaactaactt gtcttgaact aatattcctg gggtgcaaac gccttttcat ttccttattt
74821 tgcgcagaat ctgcaatcga cctacttgga ttttttgttg attctacggg actggtcgtg
74881 acactagatg tggatatatt tcttgtatgt tgattttttg ctgacttact tgtatcatta
74941 aaagaatatt gattggatga tgtaacgttg tttgttatca aaatcgaaaa caatttcatg
75001 catgccctta atttgtcctt tagtgacaga acgccggcac tatgagctaa tttttgaaaa
75061 gctctaacca ccaagtggaa tatcgatgtc tctaaggagg tcgaatataa aaagagtttg
75121 tttagctcaa ataggccaga aaacaggccg ctataaacct ttacaactgt cgaatcattt
75181 ccagttccct cttcacgttc tttgtcctca attttcttct ctaggggaga gctttccaga
75241 gccgatttgt tcaacccctc gcataagtgg ttacagatgg tcagaattaa tgatataatg
75301 taagtaatat taatggacgg agcgtttgat ttgtccaata aatgcataaa ctttgtttta
75361 actgtagagt tttcagtagt tatcaaggga gaatccattt tctcgactac ttttgatggc
75421 gccaagaaag taatatactc tggcgaattt aataagacaa tacattcttt caaaagatat
75481 ttgaacacat gttttttatc tggataatta tcatagtcca tatagagtgt attgacgatt
75541 tcggggtctt gtgataaatc cttgaaaagt tctagagata gtactctttg ccatccactt
75601 aaattggatt cgacagatat gccatggatt aacagcgaca agatgacctc taattctaac
75661 tcgagtatgc ttaggtactc ttttcttatc aacaacttca aacaacgaca actccttaca
75721 gcggtggaga agtgtctcga agaagatatg caacgtagaa gcaatggaat cgccttaact
75781 ctcagtagat attgtaaatc ttggcattct aaaagatttt tctgactatt cttcaaaatc
75841 gattcaagga tttccaggcc atagtctatt gggatgtccc caatgtctaa cagcatctcc
75901 tcgtcactaa ctgccccatt tgagcttatt tcatttaatg aacagatatt atcgaacaat
75961 ttgttagcat cgtatctata aacattgacc ttaattgact cactattact tatgaggact
76021 tcatattgtt tatcatccac tacagattca atggaaagcc tatcaaatat ttcatcgata
76081 agctgctgta aagtggcact cgcagtacca actactacgg gtgccttatt aggtacatgc
76141 agcagatttg agcaacacag caacaacttc ttacaaagcg gcccatagat gaacttcccg
76201 tatgtcttaa aaaaaatggg taccacctgt aaaactttta attgaatctc catcgcgaga
76261 tgagtagcct caatgaaggc atccaaaatt tcagacagcc ggcttcgagg aatagatgga
76321 acggttgaca gtccctgtag gcattgcatt gccagggtcg tcattttagc attccttgat
76381 tggcaagcca acacgaaagg gagtgcgaaa tccggatgtc tttctagctc ctcaaaacta
76441 tgtactcttt tcaatatctc aatggattta tcactagcat ggcgaatggt tgaatttctt
76501 cttttcgatt cggaagataa agaacgcaat tctgcttcaa gttgcctttg catggagtca
76561 aaccctccag tgttcatggc catatgaatg gtgtgtaaca ggtcaagttg gtttactttc
76621 tttgaaaatc acttgtattg catacagtct acaggcttta tttagctggg cttaggtcac
76681 cttaattatt aacacggacg atttaaaggt catccacgac gaccagccgg ctttatcaga
76741 aagtgggata atgaagactt cgcaatgact ttatgaagaa taagagcagg aggtttgagg
76801 aagtctgcaa ctcgatctga agagagtatt tgttagctgc taggacaata ttggtatacc
76861 cctttagtgt gctcaatttt tggtgaaagc agaccgtatc attagatcat tgcagaagta
76921 gtgagattta gtcgtacgtt acgtcatgga acaccaagca cttcgaaggc ttgtactgta
76981 ctgccccaat ttcatccgac gtggtgctct taggcaaaat atgactagag tgagctgtag
77041 acatatgtca ggcaagggtg gagggagaga tgagaaaggt gattgcaatg aagaaaagga
77101 ttcttccaaa gatttgggga gggtaccgtc gaagatgaaa cgagcatatg atggtgaaac
77161 agttattaaa gagggagatt cgcatgctga gtcgctagcg cagcagggaa agcagcccac
77221 agacctcgca tataacagca gatcgaagat atctggttct aatttgcatt tattggttcc
77281 tagagttgcg tctacagact atatttcgaa taaagaggtt cacacggagg gcctgtttgc
77341 cggctatcga cccttgtttc tggggaactc aggttttccg tctgatgcaa gaaagggtaa
77401 aaactttcat gagttagacg acgttcttcc caatatacag gtagtggacg cttccgagaa
77461 agatggcaaa ctcaatgtgc aggagattat tgaggactta caaagaacaa gtttgagaga
77521 aagcattcat agtatggaac agttaccatc ttcgcacaaa cgtaaacccg taataccgtg
77581 ggacgcatct ataagtggca tggtttataa tgacatgcct ttcaaatatg tgcccaaaaa
77641 tattattctg aaaatgaagc catttaaact tttgcgtatt gagagaaaaa gtcaagcgaa
77701 gaatgcaaga aagcctacta tgataaaact tcagtttcac aatcgaagaa tcaatgacac
77761 cccagagtta gtgaatttat accataataa atcccgtttg cacgagtcac tttacaatac
77821 aaaacccctt caagaatctg gatattcaag tgcaaataca agtaaaagac agaaaatgtt
77881 aaaagcaaga agcgactttg aacataaaca gaaaaattat gcatacaaac acacatttat
77941 caaaaatgat caggaactgt tccgcaatga actaactaag ttaaataaga tacttgctag
78001 agaattcaaa aaattgacaa agctatccat acataatgag ttcaagagag aacacttgcc
78061 cctggccgtt tatgtgagca aatcaaaggg cacaaagaaa ctgtttagaa gatcactgaa
78121 gatgaaaatc atggaccaca tatacccagt ttataccacg atattgtcaa ctttaacaaa
78181 ttccagagac tctaagaaat ttgaaaacaa aatcaaggcg tatattgaaa aaatcatagt
78241 gcggttatca gatgaagtac catccacata ttttttccaa gatggcgtag attgtattat
78301 tcaaccaagt ccgattcata atttcaagag aatgcattgg ttaagataca ccaagaggca
78361 caataccttt tgggggagga ctatacataa ggacgttcaa gtcagcttca atgacaagta
78421 tgttgttact aggagcggcg tgaggtatac gaggtatccc actaatttga atacacaatt
78481 attggaaact gcatttgaag aatgggacta ctatgagtga ttttgcattg agtacttatc
78541 cactgctcta ttatgtgaca tattcgcaat tcgtgtaaat attatgcata tgcatcttga
78601 gcatgcatgg aatatataaa tatgtaggtt tgttgtaata ctgtttctgc tgtgtccttc
78661 aaatatggcc tatatggtcg ctggtaaaag tggca 