GenomeNet

Database: RefSeq
Entry: NC_008769
LinkDB: NC_008769
Original site: NC_008769 
LOCUS       NC_008769            4374522 bp    DNA     circular CON 10-JUN-2013
DEFINITION  Mycobacterium bovis BCG str. Pasteur 1173P2 chromosome, complete
            genome.
ACCESSION   NC_008769
VERSION     NC_008769.1  GI:121635883
DBLINK      Project: 58781
            BioProject: PRJNA58781
KEYWORDS    RefSeq; complete genome.
SOURCE      Mycobacterium bovis BCG str. Pasteur 1173P2
  ORGANISM  Mycobacterium bovis BCG str. Pasteur 1173P2
            Bacteria; Actinobacteria; Actinobacteridae; Actinomycetales;
            Corynebacterineae; Mycobacteriaceae; Mycobacterium; Mycobacterium
            tuberculosis complex.
REFERENCE   1  (bases 1 to 4374522)
  AUTHORS   Brosch,R., Gordon,S.V., Garnier,T., Eiglmeier,K., Frigui,W.,
            Valenti,P., Dos Santos,S., Duthoy,S., Lacroix,C., Garcia-Pelayo,C.,
            Inwald,J.K., Golby,P., Garcia,J.N., Hewinson,R.G., Behr,M.A.,
            Quail,M.A., Churcher,C., Barrell,B.G., Parkhill,J. and Cole,S.T.
  TITLE     Genome plasticity of BCG and impact on vaccine efficacy
  JOURNAL   Proc. Natl. Acad. Sci. U.S.A. 104 (13), 5596-5601 (2007)
   PUBMED   17372194
REFERENCE   2  (bases 1 to 4374522)
  CONSRTM   NCBI Genome Project
  TITLE     Direct Submission
  JOURNAL   Submitted (10-JAN-2007) National Center for Biotechnology
            Information, NIH, Bethesda, MD 20894, USA
REFERENCE   3  (bases 1 to 4374522)
  AUTHORS   Garnier,T.
  TITLE     Direct Submission
  JOURNAL   Submitted (23-OCT-2006) Garnier T., Unite Genetique Moleculaire
            Bacterienne, Institut Pasteur, 28,rue du Dr ROUX, PARIS, 75015,
            FRANCE. Garnier T., submitted on behalf of the Mycobacterium bovis
            sequencing teams, TB Research Group, Veterinary Laboratories Agency
            Weybridge, Woodham Lane, New Haw,Addlestone, Surrey KT15 3NB, UK.
            Sanger Centre, Wellcome Trust Genome Campus, Hinxton,Cambridge CB10
            1SA, UK. PT4 Annotation, Genopole, Institut Pasteur, 28 Rue du
            Docteur Roux, 75724 Paris Cedex 15, France. Unite de Genetique
            Moleculaire Bacterienne, Institut Pasteur, 28 rue du Docteur Roux,
            75724 Paris Cedex 15, France
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from AM408590.
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..4374522
                     /organism="Mycobacterium bovis BCG str. Pasteur 1173P2"
                     /mol_type="genomic DNA"
                     /strain="BCG Pasteur 1173P2"
                     /db_xref="taxon:410289"
     gene            1..1524
                     /gene="dnaA"
                     /locus_tag="BCG_0001"
                     /db_xref="GeneID:4697358"
     CDS             1..1524
                     /gene="dnaA"
                     /locus_tag="BCG_0001"
                     /note="binds to the dnaA-box as an ATP-bound complex at
                     the origin of replication during the initiation of
                     chromosomal replication; can also affect transcription of
                     multiple genes including itself."
                     /codon_start=1
                     /transl_table=11
                     /product="chromosomal replication initiation protein"
                     /protein_id="YP_976107.1"
                     /db_xref="GI:121635884"
                     /db_xref="GeneID:4697358"
                     /translation="MTDDPGSGFTTVWNAVVSELNGDPKVDDGPSSDANLSAPLTPQQ
                     RAWLNLVQPLTIVEGFALLSVPSSFVQNEIERHLRAPITDALSRRLGHQIQLGVRIAP
                     PATDEADDTTVPPSENPATTSPDTTTDNDEIDDSAAARGDNQHSWPSYFTERPRNTDS
                     ATAGVTSLNRRYTFDTFVIGASNRFAHAAALAIAEAPARAYNPLFIWGESGLGKTHLL
                     HAAGNYAQRLFPGMRVKYVSTEEFTNDFINSLRDDRKVAFKRSYRDVDVLLVDDIQFI
                     EGKEGIQEEFFHTFNTLHNANKQIVISSDRPPKQLATLEDRLRTRFEWGLITDVQPPE
                     LETRIAILRKKAQMERLAVPDDVLELIASSIERNIRELEGALIRVTAFASLNKTPIDK
                     ALAEIVLRDLIADANTMQISAATIMAATAEYFDTTVEELRGPGKTRALAQSRQIAMYL
                     CRELTDLSLPKIGQAFGRDHTTVMYAQRKILSEMAERREVFDHVKELTTRIRQRSKR"
     misc_feature    1..1512
                     /gene="dnaA"
                     /locus_tag="BCG_0001"
                     /note="chromosomal replication initiation protein;
                     Provisional; Region: dnaA; PRK14086"
                     /db_xref="CDD:237605"
     misc_feature    595..978
                     /gene="dnaA"
                     /locus_tag="BCG_0001"
                     /note="The AAA+ (ATPases Associated with a wide variety of
                     cellular Activities) superfamily represents an ancient
                     group of ATPases belonging to the ASCE (for additional
                     strand, catalytic E) division of the P-loop NTPase fold.
                     The ASCE division also includes ABC; Region: AAA; cd00009"
                     /db_xref="CDD:99707"
     misc_feature    622..645
                     /gene="dnaA"
                     /locus_tag="BCG_0001"
                     /note="Walker A motif; other site"
                     /db_xref="CDD:99707"
     misc_feature    order(625..648,811..813,910..912)
                     /gene="dnaA"
                     /locus_tag="BCG_0001"
                     /note="ATP binding site [chemical binding]; other site"
                     /db_xref="CDD:99707"
     misc_feature    799..816
                     /gene="dnaA"
                     /locus_tag="BCG_0001"
                     /note="Walker B motif; other site"
                     /db_xref="CDD:99707"
     misc_feature    949..951
                     /gene="dnaA"
                     /locus_tag="BCG_0001"
                     /note="arginine finger; other site"
                     /db_xref="CDD:99707"
     misc_feature    1243..1503
                     /gene="dnaA"
                     /locus_tag="BCG_0001"
                     /note="C-terminal domain of bacterial DnaA proteins. The
                     DNA-binding C-terminal domain of DnaA contains a
                     helix-turn-helix motif that specifically interacts with
                     the DnaA box, a 9-mer motif that occurs repetitively in
                     the replication origin oriC. Multiple...; Region:
                     Bac_DnaA_C; cd06571"
                     /db_xref="CDD:119330"
     misc_feature    order(1306..1308,1330..1335,1354..1356,1372..1380,
                     1402..1416,1423..1425,1432..1437)
                     /gene="dnaA"
                     /locus_tag="BCG_0001"
                     /note="DnaA box-binding interface [nucleotide binding];
                     other site"
                     /db_xref="CDD:119330"
     gene            2052..3260
                     /gene="dnaN_1"
                     /locus_tag="BCG_0002"
                     /db_xref="GeneID:4697407"
     CDS             2052..3260
                     /gene="dnaN_1"
                     /locus_tag="BCG_0002"
                     /EC_number="2.7.7.7"
                     /note="binds the polymerase to DNA and acts as a sliding
                     clamp"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit beta"
                     /protein_id="YP_976108.1"
                     /db_xref="GI:121635885"
                     /db_xref="GeneID:4697407"
                     /translation="MDAATTRVGLTDLTFRLLRESFADAVSWVAKNLPARPAVPVLSG
                     VLLTGSDNGLTISGFDYEVSAEAQVGAEIVSPGSVLVSGRLLSDITRALPNKPVGVHV
                     EGNRVALTCGNARFSLPTMPVEDYPTLPTLPEETGLLPAELFAEAISQVAIAAGRDDT
                     LPMLTGIRVEILGETVVLAATDRFRLAVRELKWSASSPDIEAAVLVPAKTLAEAAKAG
                     IGGSDVRLSLGTGPGVGKDGLLGISGNGKRSTTRLLDAEFPKFRQLLPTEHTAVATMD
                     VAELIEAIKLVALVADRGAQVRMEFADGSVRLSAGADDVGRAEEDLVVDYAGEPLTIA
                     FNPTYLTDGLSSLRSERVSFGFTTAGKPALLRPVSGDDRPVAGLNGNGPFPAVSTDYV
                     YLLMPVRLPG"
     misc_feature    2094..3257
                     /gene="dnaN_1"
                     /locus_tag="BCG_0002"
                     /note="DNA polymerase III subunit beta; Validated; Region:
                     PRK07761"
                     /db_xref="CDD:236089"
     misc_feature    2094..3248
                     /gene="dnaN_1"
                     /locus_tag="BCG_0002"
                     /note="Beta clamp domain.  The beta subunit (processivity
                     factor) of DNA polymerase III holoenzyme, refered to as
                     the beta clamp, forms a ring shaped dimer that encircles
                     dsDNA (sliding clamp) in bacteria.  The beta-clamp is
                     structurally similar to the trimeric...; Region:
                     beta_clamp; cd00140"
                     /db_xref="CDD:238082"
     misc_feature    order(2157..2159,2301..2303,2322..2324,2676..2678)
                     /gene="dnaN_1"
                     /locus_tag="BCG_0002"
                     /note="putative DNA binding surface [nucleotide binding];
                     other site"
                     /db_xref="CDD:238082"
     misc_feature    order(2304..2306,2313..2315,2388..2390,2394..2396,
                     2916..2918,3006..3011)
                     /gene="dnaN_1"
                     /locus_tag="BCG_0002"
                     /note="dimer interface [polypeptide binding]; other site"
                     /db_xref="CDD:238082"
     misc_feature    order(2592..2594,2598..2609,3057..3059,3237..3248)
                     /gene="dnaN_1"
                     /locus_tag="BCG_0002"
                     /note="beta-clamp/clamp loader binding surface; other
                     site"
                     /db_xref="CDD:238082"
     misc_feature    order(2592..2594,2598..2603,2841..2843,2943..2945,
                     2982..2987,3066..3068,3237..3248)
                     /gene="dnaN_1"
                     /locus_tag="BCG_0002"
                     /note="beta-clamp/translesion DNA polymerase binding
                     surface; other site"
                     /db_xref="CDD:238082"
     gene            3280..4437
                     /gene="recF"
                     /locus_tag="BCG_0003"
                     /db_xref="GeneID:4695679"
     CDS             3280..4437
                     /gene="recF"
                     /locus_tag="BCG_0003"
                     /note="Required for DNA replication; binds preferentially
                     to single-stranded, linear DNA"
                     /codon_start=1
                     /transl_table=11
                     /product="recombination protein F"
                     /protein_id="YP_976109.1"
                     /db_xref="GI:121635886"
                     /db_xref="GeneID:4695679"
                     /translation="MYVRHLGLRDFRSWACVDLELHPGRTVFVGPNGYGKTNLIEALW
                     YSTTLGSHRVSADLPLIRVGTDRAVISTIVVNDGRECAVDLEIATGRVNKARLNRSSV
                     RSTRDVVGVLRAVLFAPEDLGLVRGDPADRRRYLDDLAIVRRPAIAAVRAEYERVVRQ
                     RTALLKSVPGARYRGDRGVFDTLEVWDSRLAEHGAELVAARIDLVNQLAPEVKKAYQL
                     LAPESRSASIGYRASMDVTGPSEQSDTDRQLLAARLLAALAARRDAELERGVCLVGPH
                     RDDLILRLGDQPAKGFASHGEAWSLAVALRLAAYQLLRVDGGEPVLLLDDVFAELDVM
                     RRRALATAAESAEQVLVTAAVLEDIPAGWDARRVHIDVRADDTGSMSVVLP"
     misc_feature    3280..4419
                     /gene="recF"
                     /locus_tag="BCG_0003"
                     /note="recF protein; Region: recf; TIGR00611"
                     /db_xref="CDD:233051"
     misc_feature    3286..4422
                     /gene="recF"
                     /locus_tag="BCG_0003"
                     /note="ATP-binding cassette domain of RecF; Region:
                     ABC_RecF; cd03242"
                     /db_xref="CDD:213209"
     misc_feature    3367..3390
                     /gene="recF"
                     /locus_tag="BCG_0003"
                     /note="Walker A/P-loop; other site"
                     /db_xref="CDD:213209"
     misc_feature    order(3376..3381,3385..3393,3583..3585,4252..4257,
                     4339..4341)
                     /gene="recF"
                     /locus_tag="BCG_0003"
                     /note="ATP binding site [chemical binding]; other site"
                     /db_xref="CDD:213209"
     misc_feature    3574..3585
                     /gene="recF"
                     /locus_tag="BCG_0003"
                     /note="Q-loop/lid; other site"
                     /db_xref="CDD:213209"
     misc_feature    4156..4185
                     /gene="recF"
                     /locus_tag="BCG_0003"
                     /note="ABC transporter signature motif; other site"
                     /db_xref="CDD:213209"
     misc_feature    4240..4257
                     /gene="recF"
                     /locus_tag="BCG_0003"
                     /note="Walker B; other site"
                     /db_xref="CDD:213209"
     misc_feature    4264..4275
                     /gene="recF"
                     /locus_tag="BCG_0003"
                     /note="D-loop; other site"
                     /db_xref="CDD:213209"
     misc_feature    4327..4347
                     /gene="recF"
                     /locus_tag="BCG_0003"
                     /note="H-loop/switch region; other site"
                     /db_xref="CDD:213209"
     gene            4434..4997
                     /locus_tag="BCG_0004"
                     /db_xref="GeneID:4696082"
     CDS             4434..4997
                     /locus_tag="BCG_0004"
                     /note="Differs from Mb0004 by 1aa, S16L"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_976110.1"
                     /db_xref="GI:121635887"
                     /db_xref="GeneID:4696082"
                     /translation="MTGSVDRPDQNRGERSMKSPGLDLVRRTLDEARAAARARGQDAG
                     RGRVASVASGRVAGRRRSWSGPGPDIRDPQPLGKAARELAKKRGWSVRVAEGMVLGQW
                     SAVVGHQIAEHARPTALNDGVLSVIAESTAWATQLRIMQAQLLAKIAAAVGNDVVRSL
                     KITGPAAPSWRKGPRHIAGRGPRDTYG"
     misc_feature    4437..4994
                     /locus_tag="BCG_0004"
                     /note="hypothetical protein; Provisional; Region:
                     PRK03195"
                     /db_xref="CDD:179552"
     gene            5123..7267
                     /gene="gyrB"
                     /locus_tag="BCG_0005"
                     /db_xref="GeneID:4695574"
     CDS             5123..7267
                     /gene="gyrB"
                     /locus_tag="BCG_0005"
                     /EC_number="5.99.1.3"
                     /note="negatively supercoils closed circular
                     double-stranded DNA"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA gyrase subunit B"
                     /protein_id="YP_976111.1"
                     /db_xref="GI:121635888"
                     /db_xref="GeneID:4695574"
                     /translation="MGKNEARRSALAPDHGTVVCDPLRRLNRMHATPEESIRIVAAQK
                     KKAQDEYGAASITILEGLEAVRKRPGMYIGSTGERGLHHLIWEVVDNAVDEAMAGYAT
                     TVNVVLLEDGGVEVADDGRGIPVATHASGIPTVDVVMTQLHAGGKFDSDAYAISGGLH
                     GVGVSVVNALSTRLEVEIKRDGYEWSQVYEKSEPLGLKQGAPTKKTGSTVRFWADPAV
                     FETTEYDFETVARRLQEMAFLNKGLTINLTDERVTQDEVVDEVVSDVAEAPKSASERA
                     AESTAPHKVKSRTFHYPGGLVDFVKHINRTKNAIHSSIVDFSGKGTGHEVEIAMQWNA
                     GYSESVHTFANTINTHEGGTHEEGFRSALTSVVNKYAKDRKLLKDKDPNLTGDDIREG
                     LAAVISVKVSEPQFEGQTKTKLGNTEVKSFVQKVCNEQLTHWFEANPTDSKVVVNKAV
                     SSAQARIAARKARELVRRKSATDIGGLPGKLADCRSTDPRKSELYVVEGDSAGGSAKS
                     GRDSMFQAILPLRGKIINVEKARIDRVLKNTEVQAIITALGTGIHDEFDIGKLRYHKI
                     VLMADADVDGQHISTLLLTLLFRFMRPLIENGHVFLAQPPLYKLKWQRSDPEFAYSDR
                     ERDGLLEAGLKAGKKINKEDGIQRYKGLGEMDAKELWETTMDPSVRVLRQVTLDDAAA
                     ADELFSILMGEDVDARRSFITRNAKDVRFLDV"
     misc_feature    5252..7264
                     /gene="gyrB"
                     /locus_tag="BCG_0005"
                     /note="DNA gyrase subunit B; Validated; Region: gyrB;
                     PRK05644"
                     /db_xref="CDD:235542"
     misc_feature    5363..5668
                     /gene="gyrB"
                     /locus_tag="BCG_0005"
                     /note="Histidine kinase-like ATPases; This family includes
                     several ATP-binding proteins for example: histidine
                     kinase, DNA gyrase B, topoisomerases, heat shock protein
                     HSP90, phytochrome-like ATPases and DNA mismatch repair
                     proteins; Region: HATPase_c; cd00075"
                     /db_xref="CDD:238030"
     misc_feature    order(5381..5383,5393..5395,5402..5404,5468..5470,
                     5474..5476,5480..5482,5486..5491,5603..5614,5648..5650,
                     5654..5656)
                     /gene="gyrB"
                     /locus_tag="BCG_0005"
                     /note="ATP binding site [chemical binding]; other site"
                     /db_xref="CDD:238030"
     misc_feature    5393..5395
                     /gene="gyrB"
                     /locus_tag="BCG_0005"
                     /note="Mg2+ binding site [ion binding]; other site"
                     /db_xref="CDD:238030"
     misc_feature    order(5480..5482,5486..5488,5603..5605,5609..5611)
                     /gene="gyrB"
                     /locus_tag="BCG_0005"
                     /note="G-X-G motif; other site"
                     /db_xref="CDD:238030"
     misc_feature    6002..6517
                     /gene="gyrB"
                     /locus_tag="BCG_0005"
                     /note="TopoIIA_Trans_DNA_gyrase: Transducer domain, having
                     a ribosomal S5 domain 2-like fold, of the type found in
                     proteins of the type IIA family of DNA topoisomerases
                     similar to the B subunits of E. coli DNA gyrase and E.
                     coli Topoisomerase IV which are; Region:
                     TopoII_Trans_DNA_gyrase; cd00822"
                     /db_xref="CDD:238419"
     misc_feature    6155..6157
                     /gene="gyrB"
                     /locus_tag="BCG_0005"
                     /note="anchoring element; other site"
                     /db_xref="CDD:238419"
     misc_feature    order(6329..6331,6338..6343,6347..6349,6482..6487,
                     6497..6499,6509..6511)
                     /gene="gyrB"
                     /locus_tag="BCG_0005"
                     /note="dimer interface [polypeptide binding]; other site"
                     /db_xref="CDD:238419"
     misc_feature    order(6347..6349,6353..6355)
                     /gene="gyrB"
                     /locus_tag="BCG_0005"
                     /note="ATP binding site [chemical binding]; other site"
                     /db_xref="CDD:238419"
     misc_feature    6596..6937
                     /gene="gyrB"
                     /locus_tag="BCG_0005"
                     /note="TOPRIM_TopoIIA_GyrB: topoisomerase-primase (TOPRIM)
                     nucleotidyl transferase/hydrolase domain of the type found
                     in proteins of the type IIA family of DNA topoisomerases
                     similar to the Escherichia coli GyrB subunit. TopoIIA
                     enzymes cut both strands of the...; Region:
                     TOPRIM_TopoIIA_GyrB; cd03366"
                     /db_xref="CDD:173786"
     misc_feature    order(6614..6619,6626..6628,6833..6835,6839..6841,
                     6845..6847)
                     /gene="gyrB"
                     /locus_tag="BCG_0005"
                     /note="active site"
                     /db_xref="CDD:173786"
     misc_feature    order(6614..6616,6833..6835)
                     /gene="gyrB"
                     /locus_tag="BCG_0005"
                     /note="putative metal-binding site [ion binding]; other
                     site"
                     /db_xref="CDD:173786"
     misc_feature    7025..7228
                     /gene="gyrB"
                     /locus_tag="BCG_0005"
                     /note="DNA gyrase B subunit, carboxyl terminus; Region:
                     DNA_gyraseB_C; pfam00986"
                     /db_xref="CDD:250273"
     gene            7302..9818
                     /gene="gyrA_1"
                     /locus_tag="BCG_0006"
                     /db_xref="GeneID:4695442"
     CDS             7302..9818
                     /gene="gyrA_1"
                     /locus_tag="BCG_0006"
                     /EC_number="5.99.1.3"
                     /note="negatively supercoils closed circular
                     double-stranded DNA"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA gyrase subunit A"
                     /protein_id="YP_976112.1"
                     /db_xref="GI:121635889"
                     /db_xref="GeneID:4695442"
                     /translation="MTDTTLPPDDSLDRIEPVDIQQEMQRSYIDYAMSVIVGRALPEV
                     RDGLKPVHRRVLYAMFDSGFRPDRSHAKSARSVAETMGNYHPHGDASIYDTLVRMAQP
                     WSLRYPLVDGQGNFGSPGNDPPAAMRYTEARLTPLAMEMLREIDEETVDFIPNYDGRV
                     QEPTVLPSRFPNLLANGSGGIAVGMATNIPPHNLRELADAVFWALENHDADEEETLAA
                     VMGRVKGPDFPTAGLIVGSQGTADAYKTGRGSIRMRGVVEVEEDSRGRTSLVITELPY
                     QVNHDNFITSIAEQVRDGKLAGISNIEDQSSDRVGLRIVIEIKRDAVAKVVINNLYKH
                     TQLQTSFGANMLAIVDGVPRTLRLDQLIRYYVDHQLDVIVRRTTYRLRKANERAHILR
                     GLVKALDALDEVIALIRASETVDIARAGLIELLDIDEIQAQAILDMQLRRLAALERQR
                     IIDDLAKIEAEIADLEDILAKPERQRGIVRDELAEIVDRHGDDRRTRIIAADGDVSDE
                     DLIAREDVVVTITETGYAKRTKTDLYRSQKRGGKGVQGAGLKQDDIVAHFFVCSTHDL
                     ILFFTTQGRVYRAKAYDLPEASRTARGQHVANLLAFQPEERIAQVIQIRGYTDAPYLV
                     LATRNGLVKKSKLTDFDSNRSGGIVAVNLRDNDELVGAVLCSADDDLLLVSANGQSIR
                     FSATDEALRPMGRATSGVQGMRFNIDDRLLSLNVVREGTYLLVATSGGYAKRTAIEEY
                     PVQGRGGKGVLTVMYDRRRGRLVGALIVDDDSELYAVTSGGGVIRTAARQVRKAGRQT
                     KGVRLMNLGEGDTLLAIARNAEESGDDNAVDANGADQTGN"
     misc_feature    7338..9764
                     /gene="gyrA_1"
                     /locus_tag="BCG_0006"
                     /note="DNA gyrase subunit A; Validated; Region: PRK05560"
                     /db_xref="CDD:235502"
     misc_feature    7410..8759
                     /gene="gyrA_1"
                     /locus_tag="BCG_0006"
                     /note="DNA Topoisomerase, subtype IIA; domain A';
                     bacterial DNA topoisomerase IV (C subunit, ParC),
                     bacterial DNA gyrases (A subunit, GyrA),mammalian DNA
                     toposiomerases II. DNA topoisomerases are essential
                     enzymes that regulate the conformational changes...;
                     Region: TOP4c; cd00187"
                     /db_xref="CDD:238111"
     misc_feature    order(7410..7493,7506..7655,7659..7715,7719..7790,
                     7797..7799)
                     /gene="gyrA_1"
                     /locus_tag="BCG_0006"
                     /note="CAP-like domain; other site"
                     /db_xref="CDD:238111"
     misc_feature    7686..7688
                     /gene="gyrA_1"
                     /locus_tag="BCG_0006"
                     /note="active site"
                     /db_xref="CDD:238111"
     misc_feature    order(8496..8504,8511..8522,8553..8558,8598..8648)
                     /gene="gyrA_1"
                     /locus_tag="BCG_0006"
                     /note="primary dimer interface [polypeptide binding];
                     other site"
                     /db_xref="CDD:238111"
     misc_feature    8844..8987
                     /gene="gyrA_1"
                     /locus_tag="BCG_0006"
                     /note="DNA gyrase C-terminal domain, beta-propeller;
                     Region: DNA_gyraseA_C; pfam03989"
                     /db_xref="CDD:252298"
     misc_feature    8994..9146
                     /gene="gyrA_1"
                     /locus_tag="BCG_0006"
                     /note="DNA gyrase C-terminal domain, beta-propeller;
                     Region: DNA_gyraseA_C; pfam03989"
                     /db_xref="CDD:252298"
     misc_feature    9165..9299
                     /gene="gyrA_1"
                     /locus_tag="BCG_0006"
                     /note="DNA gyrase C-terminal domain, beta-propeller;
                     Region: DNA_gyraseA_C; pfam03989"
                     /db_xref="CDD:252298"
     misc_feature    9306..9455
                     /gene="gyrA_1"
                     /locus_tag="BCG_0006"
                     /note="DNA gyrase C-terminal domain, beta-propeller;
                     Region: DNA_gyraseA_C; pfam03989"
                     /db_xref="CDD:252298"
     misc_feature    9465..9608
                     /gene="gyrA_1"
                     /locus_tag="BCG_0006"
                     /note="DNA gyrase C-terminal domain, beta-propeller;
                     Region: DNA_gyraseA_C; pfam03989"
                     /db_xref="CDD:252298"
     misc_feature    9618..9752
                     /gene="gyrA_1"
                     /locus_tag="BCG_0006"
                     /note="DNA gyrase C-terminal domain, beta-propeller;
                     Region: DNA_gyraseA_C; pfam03989"
                     /db_xref="CDD:252298"
     gene            9914..10828
                     /locus_tag="BCG_0007"
                     /db_xref="GeneID:4695440"
     CDS             9914..10828
                     /locus_tag="BCG_0007"
                     /note="Differs from Rv0007 by 1aa, I272V"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_976113.1"
                     /db_xref="GI:121635890"
                     /db_xref="GeneID:4695440"
                     /translation="MTAPNEPGALSKGDGPNADGLVDRGGAHRAATGPGRIPDAGDPP
                     PWQRAATRQSQAGHRQPPPVSHPEGRPTNPPAAADARLNRFISGASAPVTGPAAAVRT
                     PQPDPDASLGCGDGSPAEAYASELPDLSGPTPRAPQRNPAPARPAEGGAGSRGDSAAG
                     SSGGRSITAESRDARVQLSARRSRGPVRASMQIRRIDPWSTLKVSLLLSVALFFVWMI
                     TVAFLYLVLGGMGVWAKLNSNVGDLLNNASGSSAELVSSGTIFGGAFLIGLVNIVLMT
                     ALATIGAFVYNLITDLIGGIEVTLADRD"
     misc_feature    10466..10822
                     /locus_tag="BCG_0007"
                     /note="Transmembrane domain of unknown function (DUF3566);
                     Region: DUF3566; pfam12089"
                     /db_xref="CDD:152524"
     gene            10887..10960
                     /gene="tRNA-Ile"
                     /locus_tag="BCG_ileT_1"
                     /db_xref="GeneID:4696536"
     tRNA            10887..10960
                     /gene="tRNA-Ile"
                     /locus_tag="BCG_ileT_1"
                     /product="tRNA-Ile"
                     /note="ileT_1, len: 74 nt. First of two copies equivalent
                     to ileT, len: 74 nt, from Mycobacterium tuberculosis
                     strain H37Rv, (100.0% identity in 74 nt overlap).
                     tRNA-Ile, anticodon gat"
                     /anticodon=(pos:10921..10923,aa:Ile,seq:gat)
                     /codon_recognized="AUC"
                     /db_xref="GeneID:4696536"
     gene            11112..11184
                     /gene="tRNA-Ala"
                     /locus_tag="BCG_alaT_1"
                     /db_xref="GeneID:4696332"
     tRNA            11112..11184
                     /gene="tRNA-Ala"
                     /locus_tag="BCG_alaT_1"
                     /product="tRNA-Ala"
                     /note="alaT_1, len: 73 nt. First of two copies equivalent
                     to alaT, len: 73 nt, from Mycobacterium tuberculosis
                     strain H37Rv, (100.0% identity in 73 nt overlap).
                     tRNA-Ala, anticodon tgc"
                     /anticodon=(pos:11145..11147,aa:Ala,seq:tgc)
                     /codon_recognized="GCA"
                     /db_xref="GeneID:4696332"
     gene            complement(11874..12311)
                     /locus_tag="BCG_0008c"
                     /db_xref="GeneID:4697331"
     CDS             complement(11874..12311)
                     /locus_tag="BCG_0008c"
                     /note="Differs from Rv0008c by 1aa, P145S"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_976114.1"
                     /db_xref="GI:121635891"
                     /db_xref="GeneID:4697331"
                     /translation="MSEQVETRLTPRERLTRGLAYSAVGPVDVTRGLLELGVGLGLQS
                     ARSTAAGLRRRYREGRLAREVAAAQETLAQELTAAQDVVANLPQALQDARTQRRSKHH
                     LWIFAGIAAAILAGGAVAFSIVRRSSRPEPSPRPPSVEVQPRP"
     misc_feature    complement(11877..12287)
                     /locus_tag="BCG_0008c"
                     /note="Protein of unknown function (DUF2562); Region:
                     DUF2562; pfam10814"
                     /db_xref="CDD:256172"
     gene            12468..13016
                     /gene="ppiA_1"
                     /locus_tag="BCG_0009"
                     /db_xref="GeneID:4697477"
     CDS             12468..13016
                     /gene="ppiA_1"
                     /locus_tag="BCG_0009"
                     /EC_number="5.2.1.8"
                     /standard_name="cfp22"
                     /codon_start=1
                     /transl_table=11
                     /product="iron-regulated peptidyl-prolyl cis-trans
                     isomerase A ppiA"
                     /protein_id="YP_976115.1"
                     /db_xref="GI:121635892"
                     /db_xref="GeneID:4697477"
                     /translation="MADCDSVTNSPLATATATLHTNRGDIKIALFGNHAPKTVANFVG
                     LAQGTKDYSTQNASGGPSGPFYDGAVFHRVIQGFMIQGGDPTGTGRGGPGYKFADEFH
                     PELQFDKPYLLAMANAGPGTNGSQFFITVGKTPHLNRRHTIFGEVIDAESQRVVEAIS
                     KTATDGNDRPTDPVVIESITIS"
     misc_feature    12519..13001
                     /gene="ppiA_1"
                     /locus_tag="BCG_0009"
                     /note="cyclophilin: cyclophilin-type peptidylprolyl cis-
                     trans isomerases. This family contains eukaryotic,
                     bacterial and archeal proteins which exhibit a
                     peptidylprolyl cis- trans isomerases activity (PPIase,
                     Rotamase) and in addition bind the...; Region:
                     cyclophilin; cd00317"
                     /db_xref="CDD:238194"
     misc_feature    order(12684..12686,12690..12692,12699..12704,12708..12710,
                     12813..12818,12843..12845,12849..12851,12873..12878,
                     12888..12890)
                     /gene="ppiA_1"
                     /locus_tag="BCG_0009"
                     /note="active site"
                     /db_xref="CDD:238194"
     gene            complement(13222..13557)
                     /locus_tag="BCG_0010c"
                     /db_xref="GeneID:4698099"
     CDS             complement(13222..13557)
                     /locus_tag="BCG_0010c"
                     /note="In Mycobacterium bovis BCG Pasteur, and
                     Mycobacterium bovis, a single base deletion (g-*) leads to
                     a shorter product compared to its homolog in Mycobacterium
                     tuberculosis strain H37Rv (111 aa versus 141 aa)"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_976116.1"
                     /db_xref="GI:121635893"
                     /db_xref="GeneID:4698099"
                     /translation="MQQTAWAPRTSGIAGCGAGGVVMAIASVTLVTDTPGRVLTGVAA
                     LGLILFASATWRARPRLAITPDGLAIRGWFRTQLLRHSNIKIIRIDEFRRYGRLVRLL
                     EIETVSGGC"
     misc_feature    complement(<13264..13386)
                     /locus_tag="BCG_0010c"
                     /note="Bacterial PH domain; Region: bPH_6; pfam10756"
                     /db_xref="CDD:204551"
     gene            complement(13713..13994)
                     /locus_tag="BCG_0011c"
                     /db_xref="GeneID:4695508"
     CDS             complement(13713..13994)
                     /locus_tag="BCG_0011c"
                     /note="integral membrane protein involved in inhibition of
                     the Z-ring formation"
                     /codon_start=1
                     /transl_table=11
                     /product="septation inhibitor protein"
                     /protein_id="YP_976117.1"
                     /db_xref="GI:121635894"
                     /db_xref="GeneID:4695508"
                     /translation="MPKSKVRKKNDFTVSAVSRTPMKVKVGPSSVWFVSLFIGLMLIG
                     LIWLMVFQLAAIGSQAPTALNWMAQLGPWNYAIAFAFMITGLLLTMRWH"
     misc_feature    complement(13716..13994)
                     /locus_tag="BCG_0011c"
                     /note="putative septation inhibitor protein; Reviewed;
                     Region: PRK00159"
                     /db_xref="CDD:178907"
     gene            14088..14876
                     /locus_tag="BCG_0012"
                     /db_xref="GeneID:4699131"
     CDS             14088..14876
                     /locus_tag="BCG_0012"
                     /note="Differs from Rv0012 by 2aa, E105K, R233C"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_976118.1"
                     /db_xref="GI:121635895"
                     /db_xref="GeneID:4699131"
                     /translation="MRLTHPTPCPENGETMIDRRRSAWRFSVPLVCLLAGLLLAATHG
                     VSGGTEIRRSDAPRLVDLVRRAQASVNRLATEREALTTRIDSVHGRSVDTALAAMQRR
                     SAELAGVAAMNPVHGPGLVVTLQDAQRDANGRFPRDASPDDLVVHQQDIEAVLNALWN
                     AGAEAIQMQDQRIIAMSIARCVGNTLLLNGRTYSPPYTIAAIGDAAAMQAALAAAPLV
                     TLYKQYVVRFGLGYREEVHPDLQIVGYADPVRMHFAQPAGPLDY"
     misc_feature    14097..14864
                     /locus_tag="BCG_0012"
                     /note="Uncharacterized protein conserved in bacteria
                     [Function unknown]; Region: COG3879"
                     /db_xref="CDD:226396"
     gene            14913..15611
                     /gene="trpG_1"
                     /locus_tag="BCG_0013"
                     /db_xref="GeneID:4698875"
     CDS             14913..15611
                     /gene="trpG_1"
                     /locus_tag="BCG_0013"
                     /note="aminodeoxychorismate synthase subunit PabA; with
                     PabB catalyzes the formation of 4-amino-4-deoxychorismate
                     from chorismate and glutamine in para-aminobenzoate
                     synthesis; PabA provides the glutamine amidotransferase
                     activity"
                     /codon_start=1
                     /transl_table=11
                     /product="para-aminobenzoate synthase component II"
                     /protein_id="YP_976119.1"
                     /db_xref="GI:121635896"
                     /db_xref="GeneID:4698875"
                     /translation="MRILVVDNYDSFVFNLVQYLGQLGIEAEVWRNDDHRLSDEAAVA
                     GQFDGVLLSPGPGTPERAGASVSMVHACAAAHTPLLGVCLGHQAIGVAFGATVDRAPE
                     LLHGKTSSVFHTNVGVLQGLPDPFTATRYHSLTILPKSLPAVLRVTARTSSGVIMAVQ
                     HTGLPIHGVQFHPESILTEGGHRILANWLTCCGWTQDDTLVRRLENEVLTAISPHFPT
                     STASAGEATGRTSA"
     misc_feature    14919..15479
                     /gene="trpG_1"
                     /locus_tag="BCG_0013"
                     /note="Type 1 glutamine amidotransferase (GATase1) domain
                     found in Anthranilate synthase; Region:
                     GATase1_Anthranilate_Synthase; cd01743"
                     /db_xref="CDD:153214"
     misc_feature    14922..15479
                     /gene="trpG_1"
                     /locus_tag="BCG_0013"
                     /note="Glutamine amidotransferase class-I; Region: GATase;
                     pfam00117"
                     /db_xref="CDD:249601"
     misc_feature    order(15072..15077,15081..15083,15159..15164,15171..15173,
                     15303..15314)
                     /gene="trpG_1"
                     /locus_tag="BCG_0013"
                     /note="glutamine binding [chemical binding]; other site"
                     /db_xref="CDD:153214"
     misc_feature    order(15159..15161,15426..15428,15432..15434)
                     /gene="trpG_1"
                     /locus_tag="BCG_0013"
                     /note="catalytic triad [active]"
                     /db_xref="CDD:153214"
     gene            complement(15589..16734)
                     /gene="pknB"
                     /locus_tag="BCG_0014c"
                     /pseudo
                     /db_xref="GeneID:4695828"
     gene            16731..18287
                     /locus_tag="BCG_0015"
                     /pseudo
                     /db_xref="GeneID:4698696"
     repeat_region   16733..46399
                     /note="DU1, len: 29667 bases. Duplicated Region DU1. In
                     Mycobacterium bovis BCG Pasteur, the region corresponding
                     to Mycobacterium tuberculosis H37Rv
                     positions:4398597-16733 (comprising the origin of
                     replication) has been duplicated as tandem repeat at
                     position: 4361588..16732 and 16733..46399. No difference
                     has been found beetwen the two copies"
     gene            18322..18912
                     /gene="sigMa_2"
                     /locus_tag="BCG_0016"
                     /db_xref="GeneID:4696441"
     CDS             18322..18912
                     /gene="sigMa_2"
                     /locus_tag="BCG_0016"
                     /note="Member of the extracytoplasmic function sigma
                     factors which are active under specific conditions; binds
                     with the catalytic core of RNA polymerase to produce the
                     holoenzyme and directs bacterial core RNA polymerase to
                     specific promoter elements to initiate transcription: in
                     Mycobacterium bovis this protein has been shown to be
                     active at high temperatures and during stationary phase"
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase sigma factor SigM"
                     /protein_id="YP_976120.1"
                     /db_xref="GI:121635897"
                     /db_xref="GeneID:4696441"
                     /translation="MPPPIGYCPAVGFGGRHERSDAELLAAHVAGDRYAFDQLFRRHH
                     RQLHRLARLTSRTSEDADDALQDAMLSAHRGAGSFRYDAAVSSWLHRIVVNACLDRLR
                     RAKAHPTAPLEDVYPVADRTAQVETAIAVQRALMRLPVEQRAAVVAVDMQGYSIADTA
                     RMLGVAEGTVKSRCARARARLARLLGYLNTGVNIRR"
     misc_feature    18334..18906
                     /gene="sigMa_2"
                     /locus_tag="BCG_0016"
                     /note="RNA polymerase sigma factor SigM; Reviewed; Region:
                     PRK09643"
                     /db_xref="CDD:236604"
     misc_feature    18436..18639
                     /gene="sigMa_2"
                     /locus_tag="BCG_0016"
                     /note="Sigma-70 region 2; Region: Sigma70_r2; pfam04542"
                     /db_xref="CDD:252661"
     misc_feature    18709..18840
                     /gene="sigMa_2"
                     /locus_tag="BCG_0016"
                     /note="Sigma-70, region 4; Region: Sigma70_r4_2;
                     pfam08281"
                     /db_xref="CDD:203898"
     misc_feature    order(18736..18738,18766..18768,18784..18789,18817..18819,
                     18823..18828,18832..18840)
                     /gene="sigMa_2"
                     /locus_tag="BCG_0016"
                     /note="DNA binding residues [nucleotide binding]"
                     /db_xref="CDD:100119"
     gene            18801..18989
                     /gene="sigMb_2"
                     /locus_tag="BCG_0017"
                     /pseudo
                     /db_xref="GeneID:4696446"
     gene            19005..19769
                     /locus_tag="BCG_0018"
                     /db_xref="GeneID:4697289"
     CDS             19005..19769
                     /locus_tag="BCG_0018"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_976121.1"
                     /db_xref="GI:121635898"
                     /db_xref="GeneID:4697289"
                     /translation="MSAADKDPDKHSADADPPLTVELLADLQAGLLDDATAARIRSRV
                     RSDPQAQQILRALNRVRRDVAAMGADPAWGPAARPAVVDSISAALRSARPNSSPGAAH
                     AARPHVHPVRMIAGAAGLCAVATAIGVGAVVDAPPPAPSAPTTAQHITVSKPAPVIPL
                     SRPQVLDLLHHTPDYGPPGGPLGDPSRRTSCLSGLGYPASTPVLGAQPIDIDARPAVL
                     LVIPADTPDKLAVFAVAPHCSAADTGLLASTVVPRA"
     gene            19863..20870
                     /gene="trxB2_2"
                     /locus_tag="BCG_0019"
                     /db_xref="GeneID:4695650"
     CDS             19863..20870
                     /gene="trxB2_2"
                     /locus_tag="BCG_0019"
                     /EC_number="1.8.1.9"
                     /note="Differs from Rv3913 by 1aa, G57D"
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin reductase trxB2 (TRXR)"
                     /protein_id="YP_976122.1"
                     /db_xref="GI:121635899"
                     /db_xref="GeneID:4695650"
                     /translation="MTAPPVHDRAHHPVRDVIVIGSGPAGYTAALYAARAQLAPLVFE
                     GTSFGGALMTTTGVENYPGFRNGITGPELMDEMREQALRFGADLRMEDVESVSLHGPL
                     KSVVTADGQTHRARAVILAMGAAARYLQVPGEQELLGRGVSSCATCDGFFFRDQDIAV
                     IGGGDSAMEEATFLTRFARSVTLVHRRDEFRASKIMLDRARNNDKIRFLTNHTVVAVD
                     GDTTVTGLRVRDTNTGAETTLPVTGVFVAIGHEPRSGLVREAIDVDPDGYVLVQGRTT
                     STSLPGVFAAGDLVDRTYRQAVTAAGSGCAAAIDAERWLAEHAATGEADSTDALIGAQ
                     R"
     misc_feature    19908..20807
                     /gene="trxB2_2"
                     /locus_tag="BCG_0019"
                     /note="thioredoxin-disulfide reductase; Region:
                     TRX_reduct; TIGR01292"
                     /db_xref="CDD:233345"
     misc_feature    19914..20426
                     /gene="trxB2_2"
                     /locus_tag="BCG_0019"
                     /note="Short-chain dehydrogenases/reductases (SDR);
                     Region: SDR; cl21454"
                     /db_xref="CDD:271874"
     misc_feature    20334..20552
                     /gene="trxB2_2"
                     /locus_tag="BCG_0019"
                     /note="Pyridine nucleotide-disulphide oxidoreductase;
                     Region: Pyr_redox; pfam00070"
                     /db_xref="CDD:249559"
     gene            20867..21217
                     /gene="trxC_2"
                     /locus_tag="BCG_0020"
                     /db_xref="GeneID:4696834"
     CDS             20867..21217
                     /gene="trxC_2"
                     /locus_tag="BCG_0020"
                     /EC_number="1.-.-.-"
                     /standard_name="trx; trxA"
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin trxC (TRX) (MPT46)"
                     /protein_id="YP_976123.1"
                     /db_xref="GI:121635900"
                     /db_xref="GeneID:4696834"
                     /translation="MTDSEKSATIKVTDASFATDVLSSNKPVLVDFWATWCGPCKMVA
                     PVLEEIATERATDLTVAKLDVDTNPETARNFQVVSIPTLILFKDGQPVKRIVGAKGKA
                     ALLRELSDVVPNLN"
     misc_feature    20924..21190
                     /gene="trxC_2"
                     /locus_tag="BCG_0020"
                     /note="TRX family; composed of two groups: Group I, which
                     includes proteins that exclusively encode a TRX domain;
                     and Group II, which are composed of fusion proteins of TRX
                     and additional domains. Group I TRX is a small ancient
                     protein that alter the redox...; Region: TRX_family;
                     cd02947"
                     /db_xref="CDD:239245"
     misc_feature    order(20975..20977,20984..20986)
                     /gene="trxC_2"
                     /locus_tag="BCG_0020"
                     /note="catalytic residues [active]"
                     /db_xref="CDD:239245"
     gene            21327..22547
                     /locus_tag="BCG_0021"
                     /db_xref="GeneID:4697088"
     CDS             21327..22547
                     /locus_tag="BCG_0021"
                     /EC_number="3.-.-.-"
                     /codon_start=1
                     /transl_table=11
                     /product="hydrolase"
                     /protein_id="YP_976124.1"
                     /db_xref="GI:121635901"
                     /db_xref="GeneID:4697088"
                     /translation="MPSPRREDGDALRCGDRSAAVTEIRAALTALGMLDHQEEDLTTG
                     RNVALELFDAQLDQAVRAFQQHRGLLVDGIVGEATYRALKEASYRLGARTLYHQFGAP
                     LYGDDVATLQARLQDLGFYTGLVDGHFGLQTHNALMSYQREYGLAADGICGPETLRSL
                     YFLSSRVSGGSPHAIREEELVRSSGPKLSGKRIIIDPGRGGVDHGLIAQGPAGPISEA
                     DLLWDLASRLEGRMAAIGMETHLSRPTNRSPSDAERAATANAVGADLMISLRCETQTS
                     LAANGVASFHFGNSHGSVSTIGRNLADFIQREVVARTGLRDCRVHGRTWDLLRLTRMP
                     TVQVDIGYITNPHDRGMLVSTQTRDAIAEGILAAVKRLYLLGKNDRPTGTFTFAELLA
                     HELSVERAGRLGGS"
     misc_feature    21327..21806
                     /locus_tag="BCG_0021"
                     /note="Putative peptidoglycan-binding domain-containing
                     protein [Cell envelope biogenesis, outer membrane];
                     Region: COG3409"
                     /db_xref="CDD:225943"
     misc_feature    21375..21575
                     /locus_tag="BCG_0021"
                     /note="Putative peptidoglycan binding domain; Region:
                     PG_binding_1; pfam01471"
                     /db_xref="CDD:250643"
     misc_feature    21639..21806
                     /locus_tag="BCG_0021"
                     /note="Putative peptidoglycan binding domain; Region:
                     PG_binding_1; pfam01471"
                     /db_xref="CDD:250643"
     misc_feature    21825..22454
                     /locus_tag="BCG_0021"
                     /note="N-acetylmuramoyl-L-alanine amidase [Cell envelope
                     biogenesis, outer membrane]; Region: AmiC; COG0860"
                     /db_xref="CDD:223929"
     misc_feature    21900..22436
                     /locus_tag="BCG_0021"
                     /note="N-acetylmuramoyl-L-alanine amidase or MurNAc-LAA
                     (also known as peptidoglycan aminohydrolase, NAMLA
                     amidase, NAMLAA, Amidase 3, and peptidoglycan amidase; EC
                     3.5.1.28) is an autolysin that hydrolyzes the amide bond
                     between N-acetylmuramoyl and L-amino...; Region:
                     MurNAc-LAA; cd02696"
                     /db_xref="CDD:119407"
     misc_feature    order(21921..21923,21975..21977,22134..22136,22341..22343)
                     /locus_tag="BCG_0021"
                     /note="active site"
                     /db_xref="CDD:119407"
     misc_feature    order(21921..21923,21975..21977,22134..22136)
                     /locus_tag="BCG_0021"
                     /note="metal binding site [ion binding]; metal-binding
                     site"
                     /db_xref="CDD:119407"
     gene            complement(22568..23302)
                     /locus_tag="BCG_0022c"
                     /db_xref="GeneID:4695702"
     CDS             complement(22568..23302)
                     /locus_tag="BCG_0022c"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_976125.1"
                     /db_xref="GI:121635902"
                     /db_xref="GeneID:4695702"
                     /translation="MSARITALRLEAFEQLPKHARRCVFWEVDPAILGKDDHLADPEF
                     EKEAWLSMVMLEWGSCGQVATAVPDERSHAEPPCLGYVLYAPPSAVPRAQRFPTAPVS
                     ADAVLLTSMGIERGQADDDLPHSLIARVIEELVRRGVRALEAFGRTPAATDLQNPGAV
                     TPDVRPVLEALGDCCVEHCIIDANFLMDVGFVVVAPHPYFPRLRLELDKGLGWKAEVE
                     AALERLLENARLQEPIAAGSTAGNTS"
     gene            complement(23592..24626)
                     /gene="parB_2"
                     /locus_tag="BCG_0023c"
                     /db_xref="GeneID:4695600"
     CDS             complement(23592..24626)
                     /gene="parB_2"
                     /locus_tag="BCG_0023c"
                     /codon_start=1
                     /transl_table=11
                     /product="chromosome partitioning protein parB"
                     /protein_id="YP_976126.1"
                     /db_xref="GI:121635903"
                     /db_xref="GeneID:4695600"
                     /translation="MTQPSRRKGGLGRGLAALIPTGPADGESGPPTLGPRMGSATADV
                     VIGGPVPDTSVMGAIYREIPPSAIEANPRQPRQVFDEEALAELVHSIREFGLLQPIVV
                     RSLAGSQTGVRYQIVMGERRWRAAQEAGLATIPAIVRETGDDNLLRDALLENIHRVQL
                     NPLEEAAAYQQLLDEFGVTHDELAARIGRSRPLITNMIRLLKLPIPVQRRVAAGVLSA
                     GHARALLSLEAGPEAQEELASRIVAEGLSVRATEETVTLANHEANRQAHHSDATTPAP
                     PRRKPIQMPGLQDVAERLSTTFDTRVTVSLGKRKGKIVVEFGSVDDLARIVGLMTTDG
                     RDKGLHRDAL"
     misc_feature    complement(23904..24461)
                     /gene="parB_2"
                     /locus_tag="BCG_0023c"
                     /note="ParB/RepB/Spo0J family partition protein; Region:
                     parB_part; TIGR00180"
                     /db_xref="CDD:232860"
     misc_feature    complement(24162..24446)
                     /gene="parB_2"
                     /locus_tag="BCG_0023c"
                     /note="ParB-like nuclease domain; Region: ParBc;
                     pfam02195"
                     /db_xref="CDD:251149"
     misc_feature    complement(23853..24104)
                     /gene="parB_2"
                     /locus_tag="BCG_0023c"
                     /note="KorB domain; Region: KorB; pfam08535"
                     /db_xref="CDD:254862"
     gene            complement(24623..25666)
                     /gene="parA_2"
                     /locus_tag="BCG_0024c"
                     /db_xref="GeneID:4697551"
     CDS             complement(24623..25666)
                     /gene="parA_2"
                     /locus_tag="BCG_0024c"
                     /codon_start=1
                     /transl_table=11
                     /product="chromosome partitioning protein parA"
                     /protein_id="YP_976127.1"
                     /db_xref="GI:121635904"
                     /db_xref="GeneID:4697551"
                     /translation="MSAPWGPVAAGPSALVRSGQASTIEPFQREMTPPTPTPEAAHNP
                     TMNVSRETSTEFDTPIGAAAERAMRVLHTTHEPLQRPGRRRVLTIANQKGGVGKTTTA
                     VNIAAALAVQGLKTLVIDLDPQGNASTALGITDRQSGTPSSYEMLIGEVSLHTALRRS
                     PHSERLFCIPATIDLAGAEIELVSMVARENRLRTALAALDNFDFDYVFVDCPPSLGLL
                     TINALVAAPEVMIPIQCEYYALEGVSQLMRNIEMVKAHLNPQLEVTTVILTMYDGRTK
                     LADQVADEVRQYFGSKVLRTVIPRSVKVSEAPGYSMTIIDYDPGSRGAMSYLDASREL
                     AERDRPPSAKGRP"
     misc_feature    complement(24656..25414)
                     /gene="parA_2"
                     /locus_tag="BCG_0024c"
                     /note="ATPases involved in chromosome partitioning [Cell
                     division and chromosome partitioning]; Region: Soj;
                     COG1192"
                     /db_xref="CDD:224113"
     misc_feature    complement(24860..25411)
                     /gene="parA_2"
                     /locus_tag="BCG_0024c"
                     /note="ParA and ParB of Caulobacter crescentus belong to a
                     conserved family of bacterial proteins implicated in
                     chromosome segregation. ParB binds to DNA sequences
                     adjacent to the origin of replication and localizes to
                     opposite cell poles shortly following the...; Region:
                     ParA; cd02042"
                     /db_xref="CDD:238997"
     misc_feature    complement(25370..25390)
                     /gene="parA_2"
                     /locus_tag="BCG_0024c"
                     /note="P-loop; other site"
                     /db_xref="CDD:238997"
     misc_feature    complement(order(25037..25039,25370..25372))
                     /gene="parA_2"
                     /locus_tag="BCG_0024c"
                     /note="Magnesium ion binding site [ion binding]; other
                     site"
                     /db_xref="CDD:238997"
     gene            complement(25663..26337)
                     /gene="gidB"
                     /locus_tag="BCG_0025c"
                     /db_xref="GeneID:4697549"
     CDS             complement(25663..26337)
                     /gene="gidB"
                     /locus_tag="BCG_0025c"
                     /note="glucose-inhibited division protein B; SAM-dependent
                     methyltransferase; methylates the N7 position of guanosine
                     in position 527 of 16S rRNA"
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA methyltransferase GidB"
                     /protein_id="YP_976128.1"
                     /db_xref="GI:121635905"
                     /db_xref="GeneID:4697549"
                     /translation="MSPIEPAASAIFGPRLGLARRYAEALAGPGVERGLVGPREVGRL
                     WDRHLLNCAVIGELLERGDRVVDIGSGAGLPGVPLAIARPDLQVVLLEPLLRRTEFLR
                     EMVTDLGVAVEIVRGRAEESWVQDQLGGSDAAVSRAVAALDKLTKWSMPLIRPNGRML
                     AIKGERAHDEVREHRRVMIASGAVDVRVVTCGANYLRPPATVVFARRGKQIARGSARM
                     ASGGTA"
     misc_feature    complement(25756..26295)
                     /gene="gidB"
                     /locus_tag="BCG_0025c"
                     /note="rRNA small subunit methyltransferase G; Region:
                     GidB; pfam02527"
                     /db_xref="CDD:251353"
     gene            complement(26469..27032)
                     /locus_tag="BCG_0026c"
                     /db_xref="GeneID:4697395"
     CDS             complement(26469..27032)
                     /locus_tag="BCG_0026c"
                     /note="Differs from Rv3920c by 1aa, W110R"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_976129.1"
                     /db_xref="GI:121635906"
                     /db_xref="GeneID:4697395"
                     /translation="MADADTTDFDVDAEAPGGGVREDTATDADEADDQEERLVAEGEI
                     AGDYLEELLDVLDFDGDIDLDVEGNRAVVSIDGSDDLNKLVGRGGEVLDALQELTRLA
                     VHQKTGVWSRLMLDIARWRRRRREELAALADEVARRVAETGDREELVPMTPFERKIVH
                     DAVAAVPGVHSESEGVEPERRVVVLRD"
     misc_feature    complement(26472..27032)
                     /locus_tag="BCG_0026c"
                     /note="Predicted RNA-binding protein [General function
                     prediction only]; Region: Jag; COG1847"
                     /db_xref="CDD:224760"
     misc_feature    complement(26682..26894)
                     /locus_tag="BCG_0026c"
                     /note="jag_K homology RNA-binding domain. The KH domain is
                     found in proteins homologous to the Bacillus subtilis
                     protein Jag, which is associated with SpoIIIJ and is
                     necessary for the third stage of sporulation.  The KH
                     motif is a beta-alpha-alpha-beta-beta...; Region: jag_KH;
                     cd02414"
                     /db_xref="CDD:239097"
     misc_feature    complement(26766..26777)
                     /locus_tag="BCG_0026c"
                     /note="G-X-X-G motif; other site"
                     /db_xref="CDD:239097"
     misc_feature    complement(26475..26636)
                     /locus_tag="BCG_0026c"
                     /note="R3H domain found in proteins homologous to Bacillus
                     subtilus Jag, which is associated with SpoIIIJ. SpoIIIJ is
                     necessary for the third stage of sporulation. The name of
                     the R3H domain comes from the characteristic spacing of
                     the most conserved arginine...; Region: R3H_jag; cd02644"
                     /db_xref="CDD:100073"
     misc_feature    complement(order(26553..26555,26565..26567))
                     /locus_tag="BCG_0026c"
                     /note="RxxxH motif; other site"
                     /db_xref="CDD:100073"
     gene            complement(27104..28204)
                     /locus_tag="BCG_0027c"
                     /db_xref="GeneID:4696493"
     CDS             complement(27104..28204)
                     /locus_tag="BCG_0027c"
                     /note="functions to insert inner membrane proteins into
                     the IM in Escherichia coli; interacts with transmembrane
                     segments; functions in both Sec-dependent and -independent
                     membrane insertion; similar to Oxa1p in mitochondria"
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit YidC"
                     /protein_id="YP_976130.1"
                     /db_xref="GI:121635907"
                     /db_xref="GeneID:4696493"
                     /translation="MSLLFDFFSLDFIYYPVSWIMWVWYRLFAFVLGPSNFFAWALSV
                     MFLVFTLRALLYKPFVRQIRTTRQMQELQPQIKALQKKYGKDRQRMALEMQKLQREHG
                     FNPILGCLPMLAQIPVFLGLYHVLRSFNRTTGGFGQPHLSVIENRLTGNYVFSPVDVG
                     HFLDANLFGAPIGAYMTQRSGLDVFVDFSRPALIAVGVPVMILAGIATYFNSRASIAR
                     QSAEAAANPQTAMMNKLALYVFPLGVVVGGPFLPLAIILYWFSNNIWTFGQQHYVFGM
                     IEKEEEAKKQEAVRRRAANAPAPGAKPKRSPKTAPATNAAAPTEAGDTDDGAESDAST
                     ERPADTSNPARRNSGPSARTPRPGVRPKKRKR"
     misc_feature    complement(27281..28180)
                     /locus_tag="BCG_0027c"
                     /note="putative inner membrane protein translocase
                     component YidC; Provisional; Region: PRK03449"
                     /db_xref="CDD:179580"
     gene            complement(28188..28550)
                     /locus_tag="BCG_0028c"
                     /db_xref="GeneID:4697744"
     CDS             complement(28188..28550)
                     /locus_tag="BCG_0028c"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_976131.1"
                     /db_xref="GI:121635908"
                     /db_xref="GeneID:4697744"
                     /translation="MSLSRQSCGRVVRVTGRASARGLIFVIQVYRHMLSPLRPASCRF
                     VPTCSQYAVDALTEYGLLRGSWLTMIRLAKCGPWHRGGWDPIPEGLTTGRSCQTDVDG
                     ANDDWNPASKRGERESFV"
     misc_feature    complement(28236..28511)
                     /locus_tag="BCG_0028c"
                     /note="Uncharacterized conserved protein [Function
                     unknown]; Region: COG0759"
                     /db_xref="CDD:223830"
     gene            complement(28547..28924)
                     /gene="rnpA"
                     /locus_tag="BCG_0029c"
                     /db_xref="GeneID:4697864"
     CDS             complement(28547..28924)
                     /gene="rnpA"
                     /locus_tag="BCG_0029c"
                     /EC_number="3.1.26.5"
                     /note="protein component of RNaseP which catalyzes the
                     removal of the 5'-leader sequence from pre-tRNA to produce
                     the mature 5'terminus; this enzyme also cleaves other RNA
                     substrates"
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease P"
                     /protein_id="YP_976132.1"
                     /db_xref="GI:121635909"
                     /db_xref="GeneID:4697864"
                     /translation="MIATPGLFAVLRARNRMRRSADFETTVKHGMRTVRSDMVVYWWR
                     GSGGGPRVGLIIAKSVGSAVERHRVARRLRHVAGSIVKELHPSDHVVIRALPSSRHVS
                     SARLEQQLRCGLRRAVELAGSDR"
     misc_feature    complement(28550..28894)
                     /gene="rnpA"
                     /locus_tag="BCG_0029c"
                     /note="ribonuclease P; Reviewed; Region: rnpA; PRK00588"
                     /db_xref="CDD:179073"
     gene            complement(28921..29064)
                     /gene="rpmH"
                     /locus_tag="BCG_0030c"
                     /db_xref="GeneID:4696318"
     CDS             complement(28921..29064)
                     /gene="rpmH"
                     /locus_tag="BCG_0030c"
                     /note="in Escherichia coli transcription of this gene is
                     enhanced by polyamines"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L34"
                     /protein_id="YP_976133.1"
                     /db_xref="GI:121635910"
                     /db_xref="GeneID:4696318"
                     /translation="MTKGKRTFQPNNRRRARVHGFRLRMRTRAGRSIVSSRRRKGRRT
                     LSA"
     misc_feature    complement(28924..29052)
                     /gene="rpmH"
                     /locus_tag="BCG_0030c"
                     /note="50S ribosomal protein L34; Reviewed; Region: rpmH;
                     PRK00399"
                     /db_xref="CDD:179004"
     gene            29668..31191
                     /gene="dnaA"
                     /locus_tag="BCG_0031"
                     /db_xref="GeneID:4695799"
     CDS             29668..31191
                     /gene="dnaA"
                     /locus_tag="BCG_0031"
                     /note="binds to the dnaA-box as an ATP-bound complex at
                     the origin of replication during the initiation of
                     chromosomal replication; can also affect transcription of
                     multiple genes including itself."
                     /codon_start=1
                     /transl_table=11
                     /product="chromosomal replication initiation protein"
                     /protein_id="YP_976134.1"
                     /db_xref="GI:121635911"
                     /db_xref="GeneID:4695799"
                     /translation="MTDDPGSGFTTVWNAVVSELNGDPKVDDGPSSDANLSAPLTPQQ
                     RAWLNLVQPLTIVEGFALLSVPSSFVQNEIERHLRAPITDALSRRLGHQIQLGVRIAP
                     PATDEADDTTVPPSENPATTSPDTTTDNDEIDDSAAARGDNQHSWPSYFTERPRNTDS
                     ATAGVTSLNRRYTFDTFVIGASNRFAHAAALAIAEAPARAYNPLFIWGESGLGKTHLL
                     HAAGNYAQRLFPGMRVKYVSTEEFTNDFINSLRDDRKVAFKRSYRDVDVLLVDDIQFI
                     EGKEGIQEEFFHTFNTLHNANKQIVISSDRPPKQLATLEDRLRTRFEWGLITDVQPPE
                     LETRIAILRKKAQMERLAVPDDVLELIASSIERNIRELEGALIRVTAFASLNKTPIDK
                     ALAEIVLRDLIADANTMQISAATIMAATAEYFDTTVEELRGPGKTRALAQSRQIAMYL
                     CRELTDLSLPKIGQAFGRDHTTVMYAQRKILSEMAERREVFDHVKELTTRIRQRSKR"
     misc_feature    29668..31179
                     /gene="dnaA"
                     /locus_tag="BCG_0031"
                     /note="chromosomal replication initiation protein;
                     Provisional; Region: dnaA; PRK14086"
                     /db_xref="CDD:237605"
     misc_feature    30262..30645
                     /gene="dnaA"
                     /locus_tag="BCG_0031"
                     /note="The AAA+ (ATPases Associated with a wide variety of
                     cellular Activities) superfamily represents an ancient
                     group of ATPases belonging to the ASCE (for additional
                     strand, catalytic E) division of the P-loop NTPase fold.
                     The ASCE division also includes ABC; Region: AAA; cd00009"
                     /db_xref="CDD:99707"
     misc_feature    30289..30312
                     /gene="dnaA"
                     /locus_tag="BCG_0031"
                     /note="Walker A motif; other site"
                     /db_xref="CDD:99707"
     misc_feature    order(30292..30315,30478..30480,30577..30579)
                     /gene="dnaA"
                     /locus_tag="BCG_0031"
                     /note="ATP binding site [chemical binding]; other site"
                     /db_xref="CDD:99707"
     misc_feature    30466..30483
                     /gene="dnaA"
                     /locus_tag="BCG_0031"
                     /note="Walker B motif; other site"
                     /db_xref="CDD:99707"
     misc_feature    30616..30618
                     /gene="dnaA"
                     /locus_tag="BCG_0031"
                     /note="arginine finger; other site"
                     /db_xref="CDD:99707"
     misc_feature    30910..31170
                     /gene="dnaA"
                     /locus_tag="BCG_0031"
                     /note="C-terminal domain of bacterial DnaA proteins. The
                     DNA-binding C-terminal domain of DnaA contains a
                     helix-turn-helix motif that specifically interacts with
                     the DnaA box, a 9-mer motif that occurs repetitively in
                     the replication origin oriC. Multiple...; Region:
                     Bac_DnaA_C; cd06571"
                     /db_xref="CDD:119330"
     misc_feature    order(30973..30975,30997..31002,31021..31023,31039..31047,
                     31069..31083,31090..31092,31099..31104)
                     /gene="dnaA"
                     /locus_tag="BCG_0031"
                     /note="DnaA box-binding interface [nucleotide binding];
                     other site"
                     /db_xref="CDD:119330"
     gene            31719..32927
                     /gene="dnaN_2"
                     /locus_tag="BCG_0032"
                     /db_xref="GeneID:4696807"
     CDS             31719..32927
                     /gene="dnaN_2"
                     /locus_tag="BCG_0032"
                     /EC_number="2.7.7.7"
                     /note="binds the polymerase to DNA and acts as a sliding
                     clamp"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit beta"
                     /protein_id="YP_976135.1"
                     /db_xref="GI:121635912"
                     /db_xref="GeneID:4696807"
                     /translation="MDAATTRVGLTDLTFRLLRESFADAVSWVAKNLPARPAVPVLSG
                     VLLTGSDNGLTISGFDYEVSAEAQVGAEIVSPGSVLVSGRLLSDITRALPNKPVGVHV
                     EGNRVALTCGNARFSLPTMPVEDYPTLPTLPEETGLLPAELFAEAISQVAIAAGRDDT
                     LPMLTGIRVEILGETVVLAATDRFRLAVRELKWSASSPDIEAAVLVPAKTLAEAAKAG
                     IGGSDVRLSLGTGPGVGKDGLLGISGNGKRSTTRLLDAEFPKFRQLLPTEHTAVATMD
                     VAELIEAIKLVALVADRGAQVRMEFADGSVRLSAGADDVGRAEEDLVVDYAGEPLTIA
                     FNPTYLTDGLSSLRSERVSFGFTTAGKPALLRPVSGDDRPVAGLNGNGPFPAVSTDYV
                     YLLMPVRLPG"
     misc_feature    31761..32924
                     /gene="dnaN_2"
                     /locus_tag="BCG_0032"
                     /note="DNA polymerase III subunit beta; Validated; Region:
                     PRK07761"
                     /db_xref="CDD:236089"
     misc_feature    31761..32915
                     /gene="dnaN_2"
                     /locus_tag="BCG_0032"
                     /note="Beta clamp domain.  The beta subunit (processivity
                     factor) of DNA polymerase III holoenzyme, refered to as
                     the beta clamp, forms a ring shaped dimer that encircles
                     dsDNA (sliding clamp) in bacteria.  The beta-clamp is
                     structurally similar to the trimeric...; Region:
                     beta_clamp; cd00140"
                     /db_xref="CDD:238082"
     misc_feature    order(31824..31826,31968..31970,31989..31991,32343..32345)
                     /gene="dnaN_2"
                     /locus_tag="BCG_0032"
                     /note="putative DNA binding surface [nucleotide binding];
                     other site"
                     /db_xref="CDD:238082"
     misc_feature    order(31971..31973,31980..31982,32055..32057,32061..32063,
                     32583..32585,32673..32678)
                     /gene="dnaN_2"
                     /locus_tag="BCG_0032"
                     /note="dimer interface [polypeptide binding]; other site"
                     /db_xref="CDD:238082"
     misc_feature    order(32259..32261,32265..32276,32724..32726,32904..32915)
                     /gene="dnaN_2"
                     /locus_tag="BCG_0032"
                     /note="beta-clamp/clamp loader binding surface; other
                     site"
                     /db_xref="CDD:238082"
     misc_feature    order(32259..32261,32265..32270,32508..32510,32610..32612,
                     32649..32654,32733..32735,32904..32915)
                     /gene="dnaN_2"
                     /locus_tag="BCG_0032"
                     /note="beta-clamp/translesion DNA polymerase binding
                     surface; other site"
                     /db_xref="CDD:238082"
     gene            32947..34104
                     /gene="recF"
                     /locus_tag="BCG_0033"
                     /db_xref="GeneID:4697933"
     CDS             32947..34104
                     /gene="recF"
                     /locus_tag="BCG_0033"
                     /note="Required for DNA replication; binds preferentially
                     to single-stranded, linear DNA"
                     /codon_start=1
                     /transl_table=11
                     /product="recombination protein F"
                     /protein_id="YP_976136.1"
                     /db_xref="GI:121635913"
                     /db_xref="GeneID:4697933"
                     /translation="MYVRHLGLRDFRSWACVDLELHPGRTVFVGPNGYGKTNLIEALW
                     YSTTLGSHRVSADLPLIRVGTDRAVISTIVVNDGRECAVDLEIATGRVNKARLNRSSV
                     RSTRDVVGVLRAVLFAPEDLGLVRGDPADRRRYLDDLAIVRRPAIAAVRAEYERVVRQ
                     RTALLKSVPGARYRGDRGVFDTLEVWDSRLAEHGAELVAARIDLVNQLAPEVKKAYQL
                     LAPESRSASIGYRASMDVTGPSEQSDTDRQLLAARLLAALAARRDAELERGVCLVGPH
                     RDDLILRLGDQPAKGFASHGEAWSLAVALRLAAYQLLRVDGGEPVLLLDDVFAELDVM
                     RRRALATAAESAEQVLVTAAVLEDIPAGWDARRVHIDVRADDTGSMSVVLP"
     misc_feature    32947..34086
                     /gene="recF"
                     /locus_tag="BCG_0033"
                     /note="recF protein; Region: recf; TIGR00611"
                     /db_xref="CDD:233051"
     misc_feature    32953..34089
                     /gene="recF"
                     /locus_tag="BCG_0033"
                     /note="ATP-binding cassette domain of RecF; Region:
                     ABC_RecF; cd03242"
                     /db_xref="CDD:213209"
     misc_feature    33034..33057
                     /gene="recF"
                     /locus_tag="BCG_0033"
                     /note="Walker A/P-loop; other site"
                     /db_xref="CDD:213209"
     misc_feature    order(33043..33048,33052..33060,33250..33252,33919..33924,
                     34006..34008)
                     /gene="recF"
                     /locus_tag="BCG_0033"
                     /note="ATP binding site [chemical binding]; other site"
                     /db_xref="CDD:213209"
     misc_feature    33241..33252
                     /gene="recF"
                     /locus_tag="BCG_0033"
                     /note="Q-loop/lid; other site"
                     /db_xref="CDD:213209"
     misc_feature    33823..33852
                     /gene="recF"
                     /locus_tag="BCG_0033"
                     /note="ABC transporter signature motif; other site"
                     /db_xref="CDD:213209"
     misc_feature    33907..33924
                     /gene="recF"
                     /locus_tag="BCG_0033"
                     /note="Walker B; other site"
                     /db_xref="CDD:213209"
     misc_feature    33931..33942
                     /gene="recF"
                     /locus_tag="BCG_0033"
                     /note="D-loop; other site"
                     /db_xref="CDD:213209"
     misc_feature    33994..34014
                     /gene="recF"
                     /locus_tag="BCG_0033"
                     /note="H-loop/switch region; other site"
                     /db_xref="CDD:213209"
     gene            34101..34664
                     /locus_tag="BCG_0034"
                     /db_xref="GeneID:4696083"
     CDS             34101..34664
                     /locus_tag="BCG_0034"
                     /note="Differs from Mb0004 by 1aa, S16L"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_976137.1"
                     /db_xref="GI:121635914"
                     /db_xref="GeneID:4696083"
                     /translation="MTGSVDRPDQNRGERSMKSPGLDLVRRTLDEARAAARARGQDAG
                     RGRVASVASGRVAGRRRSWSGPGPDIRDPQPLGKAARELAKKRGWSVRVAEGMVLGQW
                     SAVVGHQIAEHARPTALNDGVLSVIAESTAWATQLRIMQAQLLAKIAAAVGNDVVRSL
                     KITGPAAPSWRKGPRHIAGRGPRDTYG"
     misc_feature    34104..34661
                     /locus_tag="BCG_0034"
                     /note="hypothetical protein; Provisional; Region:
                     PRK03195"
                     /db_xref="CDD:179552"
     gene            34790..36934
                     /gene="gyrB"
                     /locus_tag="BCG_0035"
                     /db_xref="GeneID:4696763"
     CDS             34790..36934
                     /gene="gyrB"
                     /locus_tag="BCG_0035"
                     /EC_number="5.99.1.3"
                     /note="negatively supercoils closed circular
                     double-stranded DNA"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA gyrase subunit B"
                     /protein_id="YP_976138.1"
                     /db_xref="GI:121635915"
                     /db_xref="GeneID:4696763"
                     /translation="MGKNEARRSALAPDHGTVVCDPLRRLNRMHATPEESIRIVAAQK
                     KKAQDEYGAASITILEGLEAVRKRPGMYIGSTGERGLHHLIWEVVDNAVDEAMAGYAT
                     TVNVVLLEDGGVEVADDGRGIPVATHASGIPTVDVVMTQLHAGGKFDSDAYAISGGLH
                     GVGVSVVNALSTRLEVEIKRDGYEWSQVYEKSEPLGLKQGAPTKKTGSTVRFWADPAV
                     FETTEYDFETVARRLQEMAFLNKGLTINLTDERVTQDEVVDEVVSDVAEAPKSASERA
                     AESTAPHKVKSRTFHYPGGLVDFVKHINRTKNAIHSSIVDFSGKGTGHEVEIAMQWNA
                     GYSESVHTFANTINTHEGGTHEEGFRSALTSVVNKYAKDRKLLKDKDPNLTGDDIREG
                     LAAVISVKVSEPQFEGQTKTKLGNTEVKSFVQKVCNEQLTHWFEANPTDSKVVVNKAV
                     SSAQARIAARKARELVRRKSATDIGGLPGKLADCRSTDPRKSELYVVEGDSAGGSAKS
                     GRDSMFQAILPLRGKIINVEKARIDRVLKNTEVQAIITALGTGIHDEFDIGKLRYHKI
                     VLMADADVDGQHISTLLLTLLFRFMRPLIENGHVFLAQPPLYKLKWQRSDPEFAYSDR
                     ERDGLLEAGLKAGKKINKEDGIQRYKGLGEMDAKELWETTMDPSVRVLRQVTLDDAAA
                     ADELFSILMGEDVDARRSFITRNAKDVRFLDV"
     misc_feature    34919..36931
                     /gene="gyrB"
                     /locus_tag="BCG_0035"
                     /note="DNA gyrase subunit B; Validated; Region: gyrB;
                     PRK05644"
                     /db_xref="CDD:235542"
     misc_feature    35030..35335
                     /gene="gyrB"
                     /locus_tag="BCG_0035"
                     /note="Histidine kinase-like ATPases; This family includes
                     several ATP-binding proteins for example: histidine
                     kinase, DNA gyrase B, topoisomerases, heat shock protein
                     HSP90, phytochrome-like ATPases and DNA mismatch repair
                     proteins; Region: HATPase_c; cd00075"
                     /db_xref="CDD:238030"
     misc_feature    order(35048..35050,35060..35062,35069..35071,35135..35137,
                     35141..35143,35147..35149,35153..35158,35270..35281,
                     35315..35317,35321..35323)
                     /gene="gyrB"
                     /locus_tag="BCG_0035"
                     /note="ATP binding site [chemical binding]; other site"
                     /db_xref="CDD:238030"
     misc_feature    35060..35062
                     /gene="gyrB"
                     /locus_tag="BCG_0035"
                     /note="Mg2+ binding site [ion binding]; other site"
                     /db_xref="CDD:238030"
     misc_feature    order(35147..35149,35153..35155,35270..35272,35276..35278)
                     /gene="gyrB"
                     /locus_tag="BCG_0035"
                     /note="G-X-G motif; other site"
                     /db_xref="CDD:238030"
     misc_feature    35669..36184
                     /gene="gyrB"
                     /locus_tag="BCG_0035"
                     /note="TopoIIA_Trans_DNA_gyrase: Transducer domain, having
                     a ribosomal S5 domain 2-like fold, of the type found in
                     proteins of the type IIA family of DNA topoisomerases
                     similar to the B subunits of E. coli DNA gyrase and E.
                     coli Topoisomerase IV which are; Region:
                     TopoII_Trans_DNA_gyrase; cd00822"
                     /db_xref="CDD:238419"
     misc_feature    35822..35824
                     /gene="gyrB"
                     /locus_tag="BCG_0035"
                     /note="anchoring element; other site"
                     /db_xref="CDD:238419"
     misc_feature    order(35996..35998,36005..36010,36014..36016,36149..36154,
                     36164..36166,36176..36178)
                     /gene="gyrB"
                     /locus_tag="BCG_0035"
                     /note="dimer interface [polypeptide binding]; other site"
                     /db_xref="CDD:238419"
     misc_feature    order(36014..36016,36020..36022)
                     /gene="gyrB"
                     /locus_tag="BCG_0035"
                     /note="ATP binding site [chemical binding]; other site"
                     /db_xref="CDD:238419"
     misc_feature    36263..36604
                     /gene="gyrB"
                     /locus_tag="BCG_0035"
                     /note="TOPRIM_TopoIIA_GyrB: topoisomerase-primase (TOPRIM)
                     nucleotidyl transferase/hydrolase domain of the type found
                     in proteins of the type IIA family of DNA topoisomerases
                     similar to the Escherichia coli GyrB subunit. TopoIIA
                     enzymes cut both strands of the...; Region:
                     TOPRIM_TopoIIA_GyrB; cd03366"
                     /db_xref="CDD:173786"
     misc_feature    order(36281..36286,36293..36295,36500..36502,36506..36508,
                     36512..36514)
                     /gene="gyrB"
                     /locus_tag="BCG_0035"
                     /note="active site"
                     /db_xref="CDD:173786"
     misc_feature    order(36281..36283,36500..36502)
                     /gene="gyrB"
                     /locus_tag="BCG_0035"
                     /note="putative metal-binding site [ion binding]; other
                     site"
                     /db_xref="CDD:173786"
     misc_feature    36692..36895
                     /gene="gyrB"
                     /locus_tag="BCG_0035"
                     /note="DNA gyrase B subunit, carboxyl terminus; Region:
                     DNA_gyraseB_C; pfam00986"
                     /db_xref="CDD:250273"
     gene            36969..39485
                     /gene="gyrA_2"
                     /locus_tag="BCG_0036"
                     /db_xref="GeneID:4695443"
     CDS             36969..39485
                     /gene="gyrA_2"
                     /locus_tag="BCG_0036"
                     /EC_number="5.99.1.3"
                     /note="negatively supercoils closed circular
                     double-stranded DNA"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA gyrase subunit A"
                     /protein_id="YP_976139.1"
                     /db_xref="GI:121635916"
                     /db_xref="GeneID:4695443"
                     /translation="MTDTTLPPDDSLDRIEPVDIQQEMQRSYIDYAMSVIVGRALPEV
                     RDGLKPVHRRVLYAMFDSGFRPDRSHAKSARSVAETMGNYHPHGDASIYDTLVRMAQP
                     WSLRYPLVDGQGNFGSPGNDPPAAMRYTEARLTPLAMEMLREIDEETVDFIPNYDGRV
                     QEPTVLPSRFPNLLANGSGGIAVGMATNIPPHNLRELADAVFWALENHDADEEETLAA
                     VMGRVKGPDFPTAGLIVGSQGTADAYKTGRGSIRMRGVVEVEEDSRGRTSLVITELPY
                     QVNHDNFITSIAEQVRDGKLAGISNIEDQSSDRVGLRIVIEIKRDAVAKVVINNLYKH
                     TQLQTSFGANMLAIVDGVPRTLRLDQLIRYYVDHQLDVIVRRTTYRLRKANERAHILR
                     GLVKALDALDEVIALIRASETVDIARAGLIELLDIDEIQAQAILDMQLRRLAALERQR
                     IIDDLAKIEAEIADLEDILAKPERQRGIVRDELAEIVDRHGDDRRTRIIAADGDVSDE
                     DLIAREDVVVTITETGYAKRTKTDLYRSQKRGGKGVQGAGLKQDDIVAHFFVCSTHDL
                     ILFFTTQGRVYRAKAYDLPEASRTARGQHVANLLAFQPEERIAQVIQIRGYTDAPYLV
                     LATRNGLVKKSKLTDFDSNRSGGIVAVNLRDNDELVGAVLCSADDDLLLVSANGQSIR
                     FSATDEALRPMGRATSGVQGMRFNIDDRLLSLNVVREGTYLLVATSGGYAKRTAIEEY
                     PVQGRGGKGVLTVMYDRRRGRLVGALIVDDDSELYAVTSGGGVIRTAARQVRKAGRQT
                     KGVRLMNLGEGDTLLAIARNAEESGDDNAVDANGADQTGN"
     misc_feature    37005..39431
                     /gene="gyrA_2"
                     /locus_tag="BCG_0036"
                     /note="DNA gyrase subunit A; Validated; Region: PRK05560"
                     /db_xref="CDD:235502"
     misc_feature    37077..38426
                     /gene="gyrA_2"
                     /locus_tag="BCG_0036"
                     /note="DNA Topoisomerase, subtype IIA; domain A';
                     bacterial DNA topoisomerase IV (C subunit, ParC),
                     bacterial DNA gyrases (A subunit, GyrA),mammalian DNA
                     toposiomerases II. DNA topoisomerases are essential
                     enzymes that regulate the conformational changes...;
                     Region: TOP4c; cd00187"
                     /db_xref="CDD:238111"
     misc_feature    order(37077..37160,37173..37322,37326..37382,37386..37457,
                     37464..37466)
                     /gene="gyrA_2"
                     /locus_tag="BCG_0036"
                     /note="CAP-like domain; other site"
                     /db_xref="CDD:238111"
     misc_feature    37353..37355
                     /gene="gyrA_2"
                     /locus_tag="BCG_0036"
                     /note="active site"
                     /db_xref="CDD:238111"
     misc_feature    order(38163..38171,38178..38189,38220..38225,38265..38315)
                     /gene="gyrA_2"
                     /locus_tag="BCG_0036"
                     /note="primary dimer interface [polypeptide binding];
                     other site"
                     /db_xref="CDD:238111"
     misc_feature    38511..38654
                     /gene="gyrA_2"
                     /locus_tag="BCG_0036"
                     /note="DNA gyrase C-terminal domain, beta-propeller;
                     Region: DNA_gyraseA_C; pfam03989"
                     /db_xref="CDD:252298"
     misc_feature    38661..38813
                     /gene="gyrA_2"
                     /locus_tag="BCG_0036"
                     /note="DNA gyrase C-terminal domain, beta-propeller;
                     Region: DNA_gyraseA_C; pfam03989"
                     /db_xref="CDD:252298"
     misc_feature    38832..38966
                     /gene="gyrA_2"
                     /locus_tag="BCG_0036"
                     /note="DNA gyrase C-terminal domain, beta-propeller;
                     Region: DNA_gyraseA_C; pfam03989"
                     /db_xref="CDD:252298"
     misc_feature    38973..39122
                     /gene="gyrA_2"
                     /locus_tag="BCG_0036"
                     /note="DNA gyrase C-terminal domain, beta-propeller;
                     Region: DNA_gyraseA_C; pfam03989"
                     /db_xref="CDD:252298"
     misc_feature    39132..39275
                     /gene="gyrA_2"
                     /locus_tag="BCG_0036"
                     /note="DNA gyrase C-terminal domain, beta-propeller;
                     Region: DNA_gyraseA_C; pfam03989"
                     /db_xref="CDD:252298"
     misc_feature    39285..39419
                     /gene="gyrA_2"
                     /locus_tag="BCG_0036"
                     /note="DNA gyrase C-terminal domain, beta-propeller;
                     Region: DNA_gyraseA_C; pfam03989"
                     /db_xref="CDD:252298"
     gene            39581..40495
                     /locus_tag="BCG_0037"
                     /db_xref="GeneID:4695441"
     CDS             39581..40495
                     /locus_tag="BCG_0037"
                     /note="Differs from Rv0007 by 1aa, I272V"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_976140.1"
                     /db_xref="GI:121635917"
                     /db_xref="GeneID:4695441"
                     /translation="MTAPNEPGALSKGDGPNADGLVDRGGAHRAATGPGRIPDAGDPP
                     PWQRAATRQSQAGHRQPPPVSHPEGRPTNPPAAADARLNRFISGASAPVTGPAAAVRT
                     PQPDPDASLGCGDGSPAEAYASELPDLSGPTPRAPQRNPAPARPAEGGAGSRGDSAAG
                     SSGGRSITAESRDARVQLSARRSRGPVRASMQIRRIDPWSTLKVSLLLSVALFFVWMI
                     TVAFLYLVLGGMGVWAKLNSNVGDLLNNASGSSAELVSSGTIFGGAFLIGLVNIVLMT
                     ALATIGAFVYNLITDLIGGIEVTLADRD"
     misc_feature    40133..40489
                     /locus_tag="BCG_0037"
                     /note="Transmembrane domain of unknown function (DUF3566);
                     Region: DUF3566; pfam12089"
                     /db_xref="CDD:152524"
     gene            40554..40627
                     /gene="tRNA-Ile"
                     /locus_tag="BCG_ileT_2"
                     /db_xref="GeneID:4697762"
     tRNA            40554..40627
                     /gene="tRNA-Ile"
                     /locus_tag="BCG_ileT_2"
                     /product="tRNA-Ile"
                     /note="ileT_2, len: 74 nt. Second of two copies equivalent
                     to ileT, len: 74 nt, from Mycobacterium tuberculosis
                     strain H37Rv, (100.0% identity in 74 nt overlap).
                     tRNA-Ile, anticodon gat"
                     /anticodon=(pos:40588..40590,aa:Ile,seq:gat)
                     /codon_recognized="AUC"
                     /db_xref="GeneID:4697762"
     gene            40779..40851
                     /gene="tRNA-Ala"
                     /locus_tag="BCG_alaT_2"
                     /db_xref="GeneID:4696333"
     tRNA            40779..40851
                     /gene="tRNA-Ala"
                     /locus_tag="BCG_alaT_2"
                     /product="tRNA-Ala"
                     /note="alaT_2, len: 73 nt. Second of two copies equivalent
                     to alaT, len: 73 nt, from Mycobacterium tuberculosis
                     strain H37Rv, (100.0% identity in 73 nt overlap).
                     tRNA-Ala, anticodon tgc"
                     /anticodon=(pos:40812..40814,aa:Ala,seq:tgc)
                     /codon_recognized="GCA"
                     /db_xref="GeneID:4696333"
     gene            complement(41541..41978)
                     /locus_tag="BCG_0038c"
                     /db_xref="GeneID:4697079"
     CDS             complement(41541..41978)
                     /locus_tag="BCG_0038c"
                     /note="Differs from Rv0008c by 1aa, P145S"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_976141.1"
                     /db_xref="GI:121635918"
                     /db_xref="GeneID:4697079"
                     /translation="MSEQVETRLTPRERLTRGLAYSAVGPVDVTRGLLELGVGLGLQS
                     ARSTAAGLRRRYREGRLAREVAAAQETLAQELTAAQDVVANLPQALQDARTQRRSKHH
                     LWIFAGIAAAILAGGAVAFSIVRRSSRPEPSPRPPSVEVQPRP"
     misc_feature    complement(41544..41954)
                     /locus_tag="BCG_0038c"
                     /note="Protein of unknown function (DUF2562); Region:
                     DUF2562; pfam10814"
                     /db_xref="CDD:256172"
     gene            42135..42683
                     /gene="ppiA_2"
                     /locus_tag="BCG_0039"
                     /db_xref="GeneID:4698839"
     CDS             42135..42683
                     /gene="ppiA_2"
                     /locus_tag="BCG_0039"
                     /EC_number="5.2.1.8"
                     /standard_name="cfp22"
                     /codon_start=1
                     /transl_table=11
                     /product="iron-regulated peptidyl-prolyl cis-trans
                     isomerase a ppiA"
                     /protein_id="YP_976142.1"
                     /db_xref="GI:121635919"
                     /db_xref="GeneID:4698839"
                     /translation="MADCDSVTNSPLATATATLHTNRGDIKIALFGNHAPKTVANFVG
                     LAQGTKDYSTQNASGGPSGPFYDGAVFHRVIQGFMIQGGDPTGTGRGGPGYKFADEFH
                     PELQFDKPYLLAMANAGPGTNGSQFFITVGKTPHLNRRHTIFGEVIDAESQRVVEAIS
                     KTATDGNDRPTDPVVIESITIS"
     misc_feature    42186..42668
                     /gene="ppiA_2"
                     /locus_tag="BCG_0039"
                     /note="cyclophilin: cyclophilin-type peptidylprolyl cis-
                     trans isomerases. This family contains eukaryotic,
                     bacterial and archeal proteins which exhibit a
                     peptidylprolyl cis- trans isomerases activity (PPIase,
                     Rotamase) and in addition bind the...; Region:
                     cyclophilin; cd00317"
                     /db_xref="CDD:238194"
     misc_feature    order(42351..42353,42357..42359,42366..42371,42375..42377,
                     42480..42485,42510..42512,42516..42518,42540..42545,
                     42555..42557)
                     /gene="ppiA_2"
                     /locus_tag="BCG_0039"
                     /note="active site"
                     /db_xref="CDD:238194"
     gene            complement(42889..43224)
                     /locus_tag="BCG_0040c"
                     /db_xref="GeneID:4698100"
     CDS             complement(42889..43224)
                     /locus_tag="BCG_0040c"
                     /note="In Mycobacterium bovis BCG Pasteur, and
                     Mycobacterium bovis, a single base deletion (g-*) leads to
                     a shorter product compared to its homolog in Mycobacterium
                     tuberculosis strain H37Rv (111 aa versus 141 aa)"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_976143.1"
                     /db_xref="GI:121635920"
                     /db_xref="GeneID:4698100"
                     /translation="MQQTAWAPRTSGIAGCGAGGVVMAIASVTLVTDTPGRVLTGVAA
                     LGLILFASATWRARPRLAITPDGLAIRGWFRTQLLRHSNIKIIRIDEFRRYGRLVRLL
                     EIETVSGGC"
     misc_feature    complement(<42931..43053)
                     /locus_tag="BCG_0040c"
                     /note="Bacterial PH domain; Region: bPH_6; pfam10756"
                     /db_xref="CDD:204551"
     gene            complement(43380..43661)
                     /locus_tag="BCG_0041c"
                     /db_xref="GeneID:4695661"
     CDS             complement(43380..43661)
                     /locus_tag="BCG_0041c"
                     /note="integral membrane protein involved in inhibition of
                     the Z-ring formation"
                     /codon_start=1
                     /transl_table=11
                     /product="septation inhibitor protein"
                     /protein_id="YP_976144.1"
                     /db_xref="GI:121635921"
                     /db_xref="GeneID:4695661"
                     /translation="MPKSKVRKKNDFTVSAVSRTPMKVKVGPSSVWFVSLFIGLMLIG
                     LIWLMVFQLAAIGSQAPTALNWMAQLGPWNYAIAFAFMITGLLLTMRWH"
     misc_feature    complement(43383..43661)
                     /locus_tag="BCG_0041c"
                     /note="putative septation inhibitor protein; Reviewed;
                     Region: PRK00159"
                     /db_xref="CDD:178907"
     gene            43755..44543
                     /locus_tag="BCG_0042"
                     /db_xref="GeneID:4698560"
     CDS             43755..44543
                     /locus_tag="BCG_0042"
                     /note="Differs from Rv0012 by 2aa, E105K, R233C"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_976145.1"
                     /db_xref="GI:121635922"
                     /db_xref="GeneID:4698560"
                     /translation="MRLTHPTPCPENGETMIDRRRSAWRFSVPLVCLLAGLLLAATHG
                     VSGGTEIRRSDAPRLVDLVRRAQASVNRLATEREALTTRIDSVHGRSVDTALAAMQRR
                     SAELAGVAAMNPVHGPGLVVTLQDAQRDANGRFPRDASPDDLVVHQQDIEAVLNALWN
                     AGAEAIQMQDQRIIAMSIARCVGNTLLLNGRTYSPPYTIAAIGDAAAMQAALAAAPLV
                     TLYKQYVVRFGLGYREEVHPDLQIVGYADPVRMHFAQPAGPLDY"
     misc_feature    43764..44531
                     /locus_tag="BCG_0042"
                     /note="Uncharacterized protein conserved in bacteria
                     [Function unknown]; Region: COG3879"
                     /db_xref="CDD:226396"
     gene            44580..45278
                     /gene="trpG_2"
                     /locus_tag="BCG_0043"
                     /db_xref="GeneID:4695708"
     CDS             44580..45278
                     /gene="trpG_2"
                     /locus_tag="BCG_0043"
                     /note="aminodeoxychorismate synthase subunit PabA; with
                     PabB catalyzes the formation of 4-amino-4-deoxychorismate
                     from chorismate and glutamine in para-aminobenzoate
                     synthesis; PabA provides the glutamine amidotransferase
                     activity"
                     /codon_start=1
                     /transl_table=11
                     /product="para-aminobenzoate synthase component II"
                     /protein_id="YP_976146.1"
                     /db_xref="GI:121635923"
                     /db_xref="GeneID:4695708"
                     /translation="MRILVVDNYDSFVFNLVQYLGQLGIEAEVWRNDDHRLSDEAAVA
                     GQFDGVLLSPGPGTPERAGASVSMVHACAAAHTPLLGVCLGHQAIGVAFGATVDRAPE
                     LLHGKTSSVFHTNVGVLQGLPDPFTATRYHSLTILPKSLPAVLRVTARTSSGVIMAVQ
                     HTGLPIHGVQFHPESILTEGGHRILANWLTCCGWTQDDTLVRRLENEVLTAISPHFPT
                     STASAGEATGRTSA"
     misc_feature    44586..45146
                     /gene="trpG_2"
                     /locus_tag="BCG_0043"
                     /note="Type 1 glutamine amidotransferase (GATase1) domain
                     found in Anthranilate synthase; Region:
                     GATase1_Anthranilate_Synthase; cd01743"
                     /db_xref="CDD:153214"
     misc_feature    44589..45146
                     /gene="trpG_2"
                     /locus_tag="BCG_0043"
                     /note="Glutamine amidotransferase class-I; Region: GATase;
                     pfam00117"
                     /db_xref="CDD:249601"
     misc_feature    order(44739..44744,44748..44750,44826..44831,44838..44840,
                     44970..44981)
                     /gene="trpG_2"
                     /locus_tag="BCG_0043"
                     /note="glutamine binding [chemical binding]; other site"
                     /db_xref="CDD:153214"
     misc_feature    order(44826..44828,45093..45095,45099..45101)
                     /gene="trpG_2"
                     /locus_tag="BCG_0043"
                     /note="catalytic triad [active]"
                     /db_xref="CDD:153214"
     gene            complement(45256..47136)
                     /gene="pknB"
                     /locus_tag="BCG_0044c"
                     /db_xref="GeneID:4695829"
     CDS             complement(45256..47136)
                     /gene="pknB"
                     /locus_tag="BCG_0044c"
                     /EC_number="2.7.1.-"
                     /codon_start=1
                     /transl_table=11
                     /product="Ser/Thr protein kinase"
                     /protein_id="YP_976147.1"
                     /db_xref="GI:121635924"
                     /db_xref="GeneID:4695829"
                     /translation="MTTPSHLSDRYELGEILGFGGMSEVHLARDLRLHRDVAVKVLRA
                     DLARDPSFYLRFRREAQNAAALNHPAIVAVYDTGEAETPAGPLPYIVMEYVDGVTLRD
                     IVHTEGPMTPKRAIEVIADACQALNFSHQNGIIHRDVKPANIMISATNAVKVMDFGIA
                     RAIADSGNSVTQTAAVIGTAQYLSPEQARGDSVDARSDVYSLGCVLYEVLTGEPPFTG
                     DSPVSVAYQHVREDPIPPSARHEGLSADLDAVVLKALAKNPENRYQTAAEMRADLVRV
                     HNGEPPEAPKVLTDAERTSLLSSAAGNLSGPRTDPLPRQDLDDTDRDRSIGSVGRWVA
                     VVAVLAVLTVVVTIAINTFGGITRDVQVPDVRGQSSADAIATLQNRGFKIRTLQKPDS
                     TIPPDHVIGTDPAANTSVSAGDEITVNVSTGPEQREIPDVSTLTYAEAVKKLTAAGFG
                     RFKQANSPSTPELVGKVIGTNPPANQTSAITNVVIIIVGSGPATKDIPDVAGQTVDVA
                     QKNLNVYGFTKFSQASVDSPRPAGEVTGTNPPAGTTVPVDSVIELQVSKGNQFVMPDL
                     SGMFWVDAEPRLRALGWTGMLDKGADVDAGGSQHNRVVYQNPPAGTGVNRDGIITLRF
                     GQ"
     misc_feature    complement(46318..47109)
                     /gene="pknB"
                     /locus_tag="BCG_0044c"
                     /note="Catalytic domain of bacterial Serine/Threonine
                     kinases, PknB and similar proteins; Region:
                     STKc_PknB_like; cd14014"
                     /db_xref="CDD:270916"
     misc_feature    complement(order(46858..46860,46906..46917,46930..46932,
                     46945..46947,47032..47037,47107..47109))
                     /gene="pknB"
                     /locus_tag="BCG_0044c"
                     /note="dimer interface [polypeptide binding]; other site"
                     /db_xref="CDD:270916"
     misc_feature    complement(46321..47106)
                     /gene="pknB"
                     /locus_tag="BCG_0044c"
                     /note="Serine/Threonine protein kinases, catalytic domain;
                     Region: S_TKc; smart00220"
                     /db_xref="CDD:214567"
     misc_feature    complement(order(46594..46605,46660..46662,46669..46674,
                     46702..46704,46708..46713,46717..46719,46723..46725,
                     46834..46836,46840..46842,46852..46863,46921..46923,
                     47017..47019,47023..47025,47062..47064,47068..47079,
                     47083..47088))
                     /gene="pknB"
                     /locus_tag="BCG_0044c"
                     /note="active site"
                     /db_xref="CDD:270916"
     misc_feature    complement(order(46669..46674,46702..46704,46708..46713,
                     46717..46719,46840..46842,46852..46863,46921..46923,
                     47017..47019,47023..47025,47062..47064,47068..47079,
                     47083..47088))
                     /gene="pknB"
                     /locus_tag="BCG_0044c"
                     /note="ATP binding site [chemical binding]; other site"
                     /db_xref="CDD:270916"
     misc_feature    complement(order(46594..46605,46660..46662,46711..46713,
                     46717..46719,46723..46725,46834..46836,46840..46842,
                     47074..47076))
                     /gene="pknB"
                     /locus_tag="BCG_0044c"
                     /note="polypeptide substrate binding site [polypeptide
                     binding]; other site"
                     /db_xref="CDD:270916"
     misc_feature    complement(order(46594..46617,46648..46674))
                     /gene="pknB"
                     /locus_tag="BCG_0044c"
                     /note="activation loop (A-loop); other site"
                     /db_xref="CDD:270916"
     misc_feature    complement(45259..46062)
                     /gene="pknB"
                     /locus_tag="BCG_0044c"
                     /note="Uncharacterized protein conserved in bacteria
                     [Function unknown]; Region: COG2815"
                     /db_xref="CDD:225372"
     misc_feature    complement(45874..46056)
                     /gene="pknB"
                     /locus_tag="BCG_0044c"
                     /note="PASTA domain of bacterial serine/threonine kinase
                     pknB-like proteins. PknB is a member of a group of related
                     transmembrane sensor kinases present in many gram positive
                     bacteria, which has been shown to regulate cell shape in
                     Mycobacterium tubercolosis; Region: PASTA_pknB; cd06577"
                     /db_xref="CDD:119328"
     misc_feature    complement(45673..45855)
                     /gene="pknB"
                     /locus_tag="BCG_0044c"
                     /note="PASTA domain of bacterial serine/threonine kinase
                     pknB-like proteins. PknB is a member of a group of related
                     transmembrane sensor kinases present in many gram positive
                     bacteria, which has been shown to regulate cell shape in
                     Mycobacterium tubercolosis; Region: PASTA_pknB; cd06577"
                     /db_xref="CDD:119328"
     misc_feature    complement(45469..45648)
                     /gene="pknB"
                     /locus_tag="BCG_0044c"
                     /note="PASTA domain of bacterial serine/threonine kinase
                     pknB-like proteins. PknB is a member of a group of related
                     transmembrane sensor kinases present in many gram positive
                     bacteria, which has been shown to regulate cell shape in
                     Mycobacterium tubercolosis; Region: PASTA_pknB; cd06577"
                     /db_xref="CDD:119328"
     misc_feature    complement(45271..45453)
                     /gene="pknB"
                     /locus_tag="BCG_0044c"
                     /note="PASTA domain of bacterial serine/threonine kinase
                     pknB-like proteins. PknB is a member of a group of related
                     transmembrane sensor kinases present in many gram positive
                     bacteria, which has been shown to regulate cell shape in
                     Mycobacterium tubercolosis; Region: PASTA_pknB; cd06577"
                     /db_xref="CDD:119328"
     gene            complement(47133..48428)
                     /gene="pknA"
                     /locus_tag="BCG_0045c"
                     /db_xref="GeneID:4696549"
     CDS             complement(47133..48428)
                     /gene="pknA"
                     /locus_tag="BCG_0045c"
                     /EC_number="2.7.1.-"
                     /codon_start=1
                     /transl_table=11
                     /product="Ser/Thr protein kinase"
                     /protein_id="YP_976148.1"
                     /db_xref="GI:121635925"
                     /db_xref="GeneID:4696549"
                     /translation="MSPRVGVTLSGRYRLQRLIATGGMGQVWEAVDNRLGRRVAVKVL
                     KSEFSSDPEFIERFRAEARTTAMLNHPGIASVHDYGESQMNGEGRTAYLVMELVNGEP
                     LNSVLKRTGRLSLRHALDMLEQTGRALQIAHAAGLVHRDVKPGNILITPTGQVKITDF
                     GIAKAVDAAPVTQTGMVMGTAQYIAPEQALGHDASPASDVYSLGVVGYEAVSGKRPFA
                     GDGALTVAMKHIKEPPPPLPPDLPPNVRELIEITLVKNPAMRYRSGGPFADAVAAVRA
                     GRRPPRPSQTPPPGRAAPAAIPSGTTARVAANSAGRTAASRRSRPATGGHRPPRRTFS
                     SGQRALLWAAGVLGALAIIIAVLLVIKAPGDNSPQQAPTPTVTTTGNPPASNTGGTDA
                     SPRLNWTERGETRHSGLQSWVVPPTPHSRASLARYEIAQ"
     misc_feature    complement(47610..48395)
                     /gene="pknA"
                     /locus_tag="BCG_0045c"
                     /note="Catalytic domain of bacterial Serine/Threonine
                     kinases, PknB and similar proteins; Region:
                     STKc_PknB_like; cd14014"
                     /db_xref="CDD:270916"
     misc_feature    complement(order(48141..48143,48192..48203,48216..48218,
                     48231..48233,48318..48323,48393..48395))
                     /gene="pknA"
                     /locus_tag="BCG_0045c"
                     /note="dimer interface [polypeptide binding]; other site"
                     /db_xref="CDD:270916"
     misc_feature    complement(47646..48392)
                     /gene="pknA"
                     /locus_tag="BCG_0045c"
                     /note="Serine/Threonine protein kinases, catalytic domain;
                     Region: S_TKc; smart00220"
                     /db_xref="CDD:214567"
     misc_feature    complement(order(47883..47894,47943..47945,47952..47957,
                     47985..47987,47991..47996,48000..48002,48006..48008,
                     48117..48119,48123..48125,48135..48146,48207..48209,
                     48303..48305,48309..48311,48348..48350,48354..48365,
                     48369..48374))
                     /gene="pknA"
                     /locus_tag="BCG_0045c"
                     /note="active site"
                     /db_xref="CDD:270916"
     misc_feature    complement(order(47952..47957,47985..47987,47991..47996,
                     48000..48002,48123..48125,48135..48146,48207..48209,
                     48303..48305,48309..48311,48348..48350,48354..48365,
                     48369..48374))
                     /gene="pknA"
                     /locus_tag="BCG_0045c"
                     /note="ATP binding site [chemical binding]; other site"
                     /db_xref="CDD:270916"
     misc_feature    complement(order(47883..47894,47943..47945,47994..47996,
                     48000..48002,48006..48008,48117..48119,48123..48125,
                     48360..48362))
                     /gene="pknA"
                     /locus_tag="BCG_0045c"
                     /note="polypeptide substrate binding site [polypeptide
                     binding]; other site"
                     /db_xref="CDD:270916"
     misc_feature    complement(order(47883..47906,47931..47957))
                     /gene="pknA"
                     /locus_tag="BCG_0045c"
                     /note="activation loop (A-loop); other site"
                     /db_xref="CDD:270916"
     gene            complement(48425..49900)
                     /gene="pbpA"
                     /locus_tag="BCG_0046c"
                     /db_xref="GeneID:4699308"
     CDS             complement(48425..49900)
                     /gene="pbpA"
                     /locus_tag="BCG_0046c"
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein pbpA"
                     /protein_id="YP_976149.1"
                     /db_xref="GI:121635926"
                     /db_xref="GeneID:4699308"
                     /translation="MNASLRRISVTVMALIVLLLLNATMTQVFTADGLRADPRNQRVL
                     LDEYSRQRGQITAGGQLLAYSVATDGRFRFLRVYPNPEVYAPVTGFYSLRYSSTALER
                     AEDPILNGSDRRLFGRRLADFFTGRDPRGGNVDTTINPRIQQAGWDAMQQGCYGPCKG
                     AVVALEPSTGKILALVSSPSYDPNLLASHNPEVQAQAWQRLGDNPASPLTNRAISETY
                     PPGSTFKVITTAAALAAGATETEQLTAAPTIPLPGSTAQLENYGGAPCGDEPTVSLRE
                     AFVKSCNTAFVQLGIRTGADALRSMARAFGLDSPPRPTPLQVAESTVGPIPDSAALGM
                     TSIGQKDVALTPLANAEIAATIANGGITMRPYLVGSLKGPDLANISTTVGYQQRRAVS
                     PQVAAKLTELMVGAEKVAQQKGAIPGVQIASKTGTAEHGTDPRHTPPHAWYIAFAPAQ
                     APKVAVAVLVENGADRLSATGGALAAPIGRAVIEAALQGEP"
     misc_feature    complement(48431..>49768)
                     /gene="pbpA"
                     /locus_tag="BCG_0046c"
                     /note="Cell division protein FtsI/penicillin-binding
                     protein 2 [Cell envelope biogenesis, outer membrane];
                     Region: FtsI; COG0768"
                     /db_xref="CDD:223839"
     misc_feature    complement(48449..49423)
                     /gene="pbpA"
                     /locus_tag="BCG_0046c"
                     /note="Penicillin binding protein transpeptidase domain;
                     Region: Transpeptidase; pfam00905"
                     /db_xref="CDD:250215"
     gene            complement(49897..51306)
                     /gene="rodA"
                     /locus_tag="BCG_0047c"
                     /db_xref="GeneID:4698833"
     CDS             complement(49897..51306)
                     /gene="rodA"
                     /locus_tag="BCG_0047c"
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein rodA"
                     /protein_id="YP_976150.1"
                     /db_xref="GI:121635927"
                     /db_xref="GeneID:4698833"
                     /translation="MTTRLQAPVAVTPPLPTRRNAELLLLCFAAVITFAALLVVQANQ
                     DQGVPWDLTSYGLAFLTLFGSAHLAIRRFAPYTDPLLLPVVALLNGLGLVMIHRLDLV
                     DNEIGEHRHPSANQQMLWTLVGVAAFALVVTFLKDHRQLARYGYICGLAGLVFLAVPA
                     LLPAALSEQNGAKIWIRLPGFSIQPAEFSKILLLIFFSAVLVAKRGLFTSAGKHLLGM
                     TLPRPRDLAPLLAAWVISVGVMVFEKDLGASLLLYTSFLVVVYLATQRFSWVVIGLTL
                     FAAGTLVAYFIFEHVRLRVQTWLDPFADPDGTGYQIVQSLFSFATGGIFGTGLGNGQP
                     DTVPAASTDFIIAAFGEELGLVGLTAILMLYTIVIIRGLRTAIATRDSFGKLLAAGLS
                     STLAIQLFIVVGGVTRLIPLTGLTTPWMSYGGSSLLANYILLAILARISHGARRPLRT
                     RPRNKSPITAAGTEVIERV"
     misc_feature    complement(49954..51096)
                     /gene="rodA"
                     /locus_tag="BCG_0047c"
                     /note="Bacterial cell division membrane protein [Cell
                     division and chromosome partitioning]; Region: FtsW;
                     COG0772"
                     /db_xref="CDD:223843"
     gene            complement(51303..52847)
                     /gene="pstP"
                     /locus_tag="BCG_0048c"
                     /db_xref="GeneID:4697710"
     CDS             complement(51303..52847)
                     /gene="pstP"
                     /locus_tag="BCG_0048c"
                     /EC_number="3.1.3.16"
                     /note="Differs from Rv0018c by 3aa, L3R, A455S, S463P"
                     /codon_start=1
                     /transl_table=11
                     /product="Serine/threonine phosphatase PPP"
                     /protein_id="YP_976151.1"
                     /db_xref="GI:121635928"
                     /db_xref="GeneID:4697710"
                     /translation="MALVTLVLRYAARSDRGLVRANNEDSVYAGARLLALADGMGGHA
                     AGEVASQLVIAALAHLDDDEPGGDLLAKLDAAVRAGNSAIAAQVEMEPDLEGMGTTLT
                     AILFAGNRLGLVHIGDSRGYLLRDGELTQITKDDTFVQTLVDEGRITPEEAHSHPQRS
                     LIMRALTGHEVEPTLTMREARAGDRYLLCSDGLSDPVSDETILEALQIPEVAESAHRL
                     IELALRGGGPDNVTVVVADVVDYDYGQTQPILAGAVSGDDDQLTLPNTAAGRASAISQ
                     RKEIVKRVPPQADTFSRPRWSGRRLAFVVALVTVLMTAGLLIGRAIIRSNYYVADYAG
                     SVSIMRGIQGSLLGMSLHQPYLMGCLSPRNELSQISYGQSGGPLDCHLMKLEDLRPPE
                     RAQVRAGLPAGTLDDAIGQLRELAANSLLPPCPAPRATSPPGRPAPPTTSETTEPNVT
                     SSPAAPSPTTSASAPTGTTPAIPTSASPAAPASPPTPWPVTSSPTMAALPPPPPQPGI
                     DCRAAA"
     misc_feature    complement(52164..52823)
                     /gene="pstP"
                     /locus_tag="BCG_0048c"
                     /note="Serine/threonine phosphatases, family 2C, catalytic
                     domain; The protein architecture and deduced catalytic
                     mechanism of PP2C phosphatases are similar to the PP1,
                     PP2A, PP2B family of protein Ser/Thr phosphatases, with
                     which PP2C shares no sequence...; Region: PP2Cc; cd00143"
                     /db_xref="CDD:238083"
     misc_feature    complement(order(52275..52277,52728..52736,52773..52778,
                     52788..52790))
                     /gene="pstP"
                     /locus_tag="BCG_0048c"
                     /note="active site"
                     /db_xref="CDD:238083"
     misc_feature    complement(51453..>51680)
                     /gene="pstP"
                     /locus_tag="BCG_0048c"
                     /note="Uncharacterized conserved protein [Function
                     unknown]; Region: COG1615; cl09133"
                     /db_xref="CDD:245017"
     gene            complement(52936..53403)
                     /locus_tag="BCG_0049c"
                     /db_xref="GeneID:4695696"
     CDS             complement(52936..53403)
                     /locus_tag="BCG_0049c"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_976152.1"
                     /db_xref="GI:121635929"
                     /db_xref="GeneID:4695696"
                     /translation="MQGLVLQLTRAGFLMLLWVFIWSVLRILKTDIYAPTGAVMMRRG
                     LALRGTLLGARQRRHAARYLVVTEGALTGARITLSEQPVLIGRADDSTLVLTDDYAST
                     RHARLSMRGSEWYVEDLGSTNGTYLDRAKVTTAVRVPIGTPVRIGKTAIELRP"
     misc_feature    complement(52948..53403)
                     /locus_tag="BCG_0049c"
                     /note="FOG: FHA domain [Signal transduction mechanisms];
                     Region: COG1716"
                     /db_xref="CDD:224630"
     misc_feature    complement(52942..53217)
                     /locus_tag="BCG_0049c"
                     /note="Forkhead associated domain (FHA); found in
                     eukaryotic and prokaryotic proteins. Putative nuclear
                     signalling domain. FHA domains may bind phosphothreonine,
                     phosphoserine and sometimes phosphotyrosine. In
                     eukaryotes, many FHA domain-containing proteins...;
                     Region: FHA; cd00060"
                     /db_xref="CDD:238017"
     misc_feature    complement(order(53032..53040,53098..53103,53107..53109,
                     53143..53145))
                     /locus_tag="BCG_0049c"
                     /note="phosphopeptide binding site; other site"
                     /db_xref="CDD:238017"
     gene            complement(53527..55092)
                     /gene="TB39.8"
                     /locus_tag="BCG_0050c"
                     /db_xref="GeneID:4697326"
     CDS             complement(53527..55092)
                     /gene="TB39.8"
                     /locus_tag="BCG_0050c"
                     /note="Differs from Mb0020c by 2aa, G47R, Y250H, and from
                     Rv0020c by 3aa, G222D, C298Y, Q378R, and deletion of 6aa
                     (EQRGYP) at position 246"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_976153.1"
                     /db_xref="GI:121635930"
                     /db_xref="GeneID:4697326"
                     /translation="MGSQKRLVQRVERKLEQTVGDAFARIFGGSIVPQEVEALLRREA
                     ADGIQSLQGNRLLAPNEYIITLGVHDFEKLGADPELKSTGFARDLADYIQEQGWQTYG
                     DVVVRFEQSSNLHTGQFRARGTVNPDVETHPPVIDCARPQSNHAFGAEPGVAPMSDNS
                     SYRGGQGQGRPDEYYDDRYARPQEDPRGGPDPQGGSDPRGGYPPETGGYPPQPGYPRP
                     RHPGQGDYPEQIGYPDQGGYPEQRGYPDQRGYQDQGRGYPDQGQGGYPPPYEQRPPVS
                     PGPAAGYGAPGYDQGYRQSGGCGPSPGGGQPGYGGYGEYGRGPARHEEGSYVPSGPPG
                     PPEQRPAYPDQGGYDQGYQQGATTYGRQDYGGGADYTRYTESPQVPGYAPQGGGYAEP
                     AGRDYDYGQSGAPDYGQPAPGGYSGYGQGGYGSAGTSVTLQLDDGSGRTYQLREGSNI
                     IGRGQDAQFRLPDTGVSRRHLEIRWDGQVALLADLNSTNGTTVNNAPVQEWQLADGDV
                     IRLGHSEIIVRMH"
     misc_feature    complement(54724..55071)
                     /gene="TB39.8"
                     /locus_tag="BCG_0050c"
                     /note="Protein of unknown function (DUF2662); Region:
                     DUF3662; pfam12401"
                     /db_xref="CDD:204906"
     misc_feature    complement(54277..>54528)
                     /gene="TB39.8"
                     /locus_tag="BCG_0050c"
                     /note="Arsenite-resistance protein 2; Region: ARS2;
                     pfam04959"
                     /db_xref="CDD:252906"
     misc_feature    complement(53536..53790)
                     /gene="TB39.8"
                     /locus_tag="BCG_0050c"
                     /note="Forkhead associated domain (FHA); found in
                     eukaryotic and prokaryotic proteins. Putative nuclear
                     signalling domain. FHA domains may bind phosphothreonine,
                     phosphoserine and sometimes phosphotyrosine. In
                     eukaryotes, many FHA domain-containing proteins...;
                     Region: FHA; cd00060"
                     /db_xref="CDD:238017"
     misc_feature    complement(53533..>53766)
                     /gene="TB39.8"
                     /locus_tag="BCG_0050c"
                     /note="FOG: FHA domain [Signal transduction mechanisms];
                     Region: COG1716"
                     /db_xref="CDD:224630"
     misc_feature    complement(order(53623..53631,53689..53694,53698..53700,
                     53734..53736))
                     /gene="TB39.8"
                     /locus_tag="BCG_0050c"
                     /note="phosphopeptide binding site; other site"
                     /db_xref="CDD:238017"
     gene            55292..55374
                     /gene="tRNA-Leu"
                     /locus_tag="BCG_t01"
                     /db_xref="GeneID:4696424"
     tRNA            55292..55374
                     /gene="tRNA-Leu"
                     /locus_tag="BCG_t01"
                     /product="tRNA-Leu"
                     /note="leuT, len: 83 nt. Equivalent to leuT, len: 83 nt,
                     from Mycobacterium tuberculosis strain H37Rv, (100.0%
                     identity in 83 nt overlap). tRNA-Leu, anticodon cag"
                     /anticodon=(pos:55325..55327,aa:Leu,seq:cag)
                     /codon_recognized="CUG"
                     /db_xref="GeneID:4696424"
     gene            complement(55561..56529)
                     /locus_tag="BCG_0051c"
                     /db_xref="GeneID:4696748"
     CDS             complement(55561..56529)
                     /locus_tag="BCG_0051c"
                     /note="Differs from Rv0021c by 1aa, P277A"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_976154.1"
                     /db_xref="GI:121635931"
                     /db_xref="GeneID:4696748"
                     /translation="MVLSTAFSQMFGIDYPIVSAPMDLIAGGELAAAVSGAGGLGLIG
                     GGYGDRDWLARQFDLAAGAPVGCGFITWSLARQPQLLDLALQYEPVAVMLSFGDPAVF
                     ADAIKSAGTRLVCQIQNRTQAERALQVGADVLVAQGTEAGGHGHGPRSTLTLVPEIVD
                     LVTARGTDIPVIAAGGIADGRGLAAALMLGAAGVLVGTRFYATVEALSTPQARDPLLA
                     ATGDDMCRTTIYDQLRRYPWPQGHTMSVLSNALTDQFEDTELDILHREEAMARYWRAV
                     PARDYSIANVTAGQAAGLVNAVLPAADVITGMAQQAARTLTAMRAV"
     misc_feature    complement(55597..56520)
                     /locus_tag="BCG_0051c"
                     /note="Nitronate monooxygenase; Region: NMO; pfam03060"
                     /db_xref="CDD:251701"
     misc_feature    complement(55837..56493)
                     /locus_tag="BCG_0051c"
                     /note="2-Nitropropane dioxygenase (NPD), one of the
                     nitroalkane oxidizing enzyme families, catalyzes oxidative
                     denitrification of nitroalkanes to their corresponding
                     carbonyl compounds and nitrites. NDP is a member of the
                     NAD(P)H-dependent flavin oxidoreductase...; Region:
                     NPD_like; cd04730"
                     /db_xref="CDD:240081"
     misc_feature    complement(order(55936..55947,56002..56010,56104..56109,
                     56119..56121,56182..56184,56245..56247,56320..56322,
                     56464..56469))
                     /locus_tag="BCG_0051c"
                     /note="FMN binding site [chemical binding]; other site"
                     /db_xref="CDD:240081"
     misc_feature    complement(56098..56103)
                     /locus_tag="BCG_0051c"
                     /note="substrate binding site [chemical binding]; other
                     site"
                     /db_xref="CDD:240081"
     misc_feature    complement(56098..56100)
                     /locus_tag="BCG_0051c"
                     /note="putative catalytic residue [active]"
                     /db_xref="CDD:240081"
     gene            complement(56671..57090)
                     /gene="whiB5"
                     /locus_tag="BCG_0052c"
                     /db_xref="GeneID:4698046"
     CDS             complement(56671..57090)
                     /gene="whiB5"
                     /locus_tag="BCG_0052c"
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulatory protein whiB-like
                     whiB5"
                     /protein_id="YP_976155.1"
                     /db_xref="GI:121635932"
                     /db_xref="GeneID:4698046"
                     /translation="MAHPCATDPELWFGYPDDDGSDGAAKARAYERSATQARIQCLRR
                     CPLLQQRRCAQHAVEHRVEYGVWAGIKLPGGQYRKREQLAAAHDVLRRIAGGEINSRQ
                     LPDNAALLARNEGLEVTPVPGVVVHLPIAQVGPQPAA"
     misc_feature    complement(56842..57057)
                     /gene="whiB5"
                     /locus_tag="BCG_0052c"
                     /note="Transcription factor WhiB; Region: Whib; pfam02467"
                     /db_xref="CDD:111373"
     gene            57243..58013
                     /locus_tag="BCG_0053"
                     /db_xref="GeneID:4697344"
     CDS             57243..58013
                     /locus_tag="BCG_0053"
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulatory protein"
                     /protein_id="YP_976156.1"
                     /db_xref="GI:121635933"
                     /db_xref="GeneID:4697344"
                     /translation="MSRESAGAAIRALRESRDWSLADLAAATGVSTMGLSYLERGARK
                     PHKSTVQKVENGLGLPPGTYSRLLVAADPDAELARLIAAQPSNPTAVRRAGAVVVDRH
                     SDTDVLEGYAEAQLDAIKSVIDRLPATTSNEYETYILSVIAQCVKAEMLAASSWRVAV
                     NAGADSTGRLMEHLRALEATRGALLERMPTSLSARFDRACAQSSLPEAVVAALIGVGA
                     DEMWDIRNRGVIPAGALPRVRAFVDAIEASHDADEGQQ"
     misc_feature    57261..>57482
                     /locus_tag="BCG_0053"
                     /note="Predicted transcriptional regulators
                     [Transcription]; Region: HipB; COG1396"
                     /db_xref="CDD:224314"
     misc_feature    57261..57425
                     /locus_tag="BCG_0053"
                     /note="Helix-turn-helix XRE-family like proteins.
                     Prokaryotic DNA binding proteins belonging to the
                     xenobiotic response element family of transcriptional
                     regulators; Region: HTH_XRE; cd00093"
                     /db_xref="CDD:238045"
     misc_feature    order(57273..57275,57285..57287,57360..57362)
                     /locus_tag="BCG_0053"
                     /note="non-specific DNA binding site [nucleotide binding];
                     other site"
                     /db_xref="CDD:238045"
     misc_feature    order(57282..57284,57357..57359)
                     /locus_tag="BCG_0053"
                     /note="salt bridge; other site"
                     /db_xref="CDD:238045"
     misc_feature    order(57303..57308,57339..57341,57348..57350,57360..57365)
                     /locus_tag="BCG_0053"
                     /note="sequence-specific DNA binding site [nucleotide
                     binding]; other site"
                     /db_xref="CDD:238045"
     gene            58010..58843
                     /locus_tag="BCG_0054"
                     /db_xref="GeneID:4697145"
     CDS             58010..58843
                     /locus_tag="BCG_0054"
                     /note="In Mycobacterium tuberculosis strain H37Rv, and
                     other mycobacteria, Rv0024 exists as a single gene. In
                     Mycobacterium bovis BCG Pasteur, and Mycobacterium bovis,
                     a frameshift due to a single base deletion (c-*) splits
                     Rv0024 into 2 parts"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_976157.1"
                     /db_xref="GI:121635934"
                     /db_xref="GeneID:4697145"
                     /translation="MNYSEVELLSRAHQLFAGDSRRPGLDAGTTPYGDLLSRAADLNV
                     GAGQRRYQLAVDHSRAALLSAARTDAAAGAVITGAQRDRAWARRSTGTVLDEARSDTT
                     VTAVMPIAQREAIRRRVARLRAQRAHVLTARRRARRHLAALRALRYRVAHGPGVALAK
                     LRLPSPSGRAGIAVHAALSRLGRPYVWGATGPTSSTVPVWSSGPTPRRVFTWIAPPIN
                     RSTRGSRCRAHRSGRAIWSSRTPGTCSWRSATIWSSRRPMRARRFGSARWATTCRFGD
                     R"
     gene            58585..58854
                     /locus_tag="BCG_0055"
                     /pseudo
                     /db_xref="GeneID:4698692"
     gene            58892..59254
                     /locus_tag="BCG_0056"
                     /db_xref="GeneID:4696316"
     CDS             58892..59254
                     /locus_tag="BCG_0056"
                     /note="Differs from Rv0025 by 1aa, L73P"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_976158.1"
                     /db_xref="GI:121635935"
                     /db_xref="GeneID:4696316"
                     /translation="MSEQAGSSVAVIQERQALLARQHDAVAEADRELADVLASAHAAM
                     RESVRRLDAIAAELDRAVPDQDQLAVDTLMGAREFQTFLVAKQREIVAVVAAAHELDR
                     AKSAVLKRLRAQYTEPAR"
     misc_feature    58898..59236
                     /locus_tag="BCG_0056"
                     /note="Domain of unknown function (DUF4226); Region:
                     DUF4226; pfam10774"
                     /db_xref="CDD:256159"
     gene            59369..60802
                     /locus_tag="BCG_0057"
                     /db_xref="GeneID:4695476"
     CDS             59369..60802
                     /locus_tag="BCG_0057"
                     /note="In Mycobacterium bovis and Mycobacterium bovis BCG
                     Pasteur, a 4 bp insertion (*-atcg) leads to a longer
                     protein with a different COOH part compared to its homolog
                     in Mycobacterium tuberculosis strain H37Rv (477 aa versus
                     448 aa). Differs from Rv0026 by 1aa, P93Q"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_976159.1"
                     /db_xref="GI:121635936"
                     /db_xref="GeneID:4695476"
                     /translation="MAFDAAMSTHEDLLATIRYVRDRTGDPNAWQTGLTPTEVTAVVT
                     STTRSEQLDAILRKIRQRHSNLYYPAPPDREQGDAARAIADAEAALAHPNSATAQLDL
                     QVVSAILNAHLKTVEGGESLHELQQEIEAAVRIRSDLDTPAGARDFQRFLIGKLKDIR
                     EVVATASLDAASKSALMAAWTSLYDASKGDRGDADDRGPASVGSGGAPARGAGQQPEL
                     PTRAEPDCLLDSLLLEDPGLLADDLQVPGGTSAAIPSASSTPSLPNLGGATMPGGGAT
                     PALVPGVSAPGGLPLSGLLRGVGDEPELTDFDERGQEVRDPADYEHSNEPDERRADDR
                     EGADEDAGLGKSESPPQAPTTVTLPNGETVTAASPQLAAAIKAAASGTPIADAFQQQG
                     IAIPLPGTAVANPVDPARISAGDVGVFTDRHALALGPSKALLDGQIQHISAVRGRNFL
                     GWIHPAATATAPARTEAPTPTRPAAAR"
     misc_feature    59588..59920
                     /locus_tag="BCG_0057"
                     /note="Domain of unknown function (DUF4226); Region:
                     DUF4226; pfam10774"
                     /db_xref="CDD:256159"
     gene            60840..61157
                     /locus_tag="BCG_0058"
                     /db_xref="GeneID:4698607"
     CDS             60840..61157
                     /locus_tag="BCG_0058"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_976160.1"
                     /db_xref="GI:121635937"
                     /db_xref="GeneID:4698607"
                     /translation="MTDRIHVQPAHLRQAAAHHQQTADYLRTVPSSHDAIRESLDSLG
                     PIFSELRDTGRELLELRKQCYQQQADNHADIAQNLRTSAAMWEQHERAASRSLGNIID
                     GSR"
     misc_feature    60840..61136
                     /locus_tag="BCG_0058"
                     /note="Protein of unknown function (DUF2580); Region:
                     DUF2580; pfam10824"
                     /db_xref="CDD:256175"
     gene            61165..61470
                     /locus_tag="BCG_0059"
                     /db_xref="GeneID:4695862"
     CDS             61165..61470
                     /locus_tag="BCG_0059"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_976161.1"
                     /db_xref="GI:121635938"
                     /db_xref="GeneID:4695862"
                     /translation="MTDANPAFDTVHPSGHILVRSCRGGYMHSVSLSEAAMETDAETL
                     AEAILLTADVSCLKALLEVRNEIVAAGHTPSAQVPTTDDLNVAIEKLLAHQLRRRNR"
     misc_feature    61165..61467
                     /locus_tag="BCG_0059"
                     /note="Protein of unknown function (DUF2694); Region:
                     DUF2694; pfam10904"
                     /db_xref="CDD:151351"
     gene            61708..62805
                     /locus_tag="BCG_0060"
                     /db_xref="GeneID:4696897"
     CDS             61708..62805
                     /locus_tag="BCG_0060"
                     /note="Differs from Rv0029 by 1aa, N190H"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_976162.1"
                     /db_xref="GI:121635939"
                     /db_xref="GeneID:4696897"
                     /translation="MAIFGRWSARQRLRRATRESLTIPTFSSSLDCTTRVIGGLWPAE
                     LSSNTAETATLAEHLKADLHRIVGSANDELMVIWRAGMADSTRRAEEDRVIDRARASA
                     MRRVESAMRELRQITGRVPVEIPRMRGAGGSDLDTTRLMPAVTVVQPADQACTDWPVA
                     AAEDDEARLQRLLAFVARQEPRLNWAVGVNADGTTVLVTDVAHGWIPPGIALPEGVRL
                     LAPARRAGRAPELVGITTCCKTYTPGDSLRRAVDSTAPTSSVQPRALPAIAGLSVELG
                     IATQRHDGLPKIVHAMATAAGNGAAAEEVDLLRVHVDTALHHVLAQYPRVDPALLLNC
                     MLLAATERSVTGDPIAANYHFAWFRELDSRR"
     gene            62875..63204
                     /locus_tag="BCG_0061"
                     /db_xref="GeneID:4695377"
     CDS             62875..63204
                     /locus_tag="BCG_0061"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_976163.1"
                     /db_xref="GI:121635940"
                     /db_xref="GeneID:4695377"
                     /translation="MVSGSDSRSEPSQLSDRDLVESVLRDLSEAADKWEALVTQAETV
                     TYSVDLGDVRAVANSDGRLLELTLHPGVMTGYAHGELADRVNLAITALRDEVEAENRA
                     RYGGRLQ"
     misc_feature    62875..63201
                     /locus_tag="BCG_0061"
                     /note="Protein of unknown function (DUF2710); Region:
                     DUF2710; pfam10921"
                     /db_xref="CDD:151368"
     gene            63233..63445
                     /locus_tag="BCG_0062"
                     /db_xref="GeneID:4696701"
     CDS             63233..63445
                     /locus_tag="BCG_0062"
                     /codon_start=1
                     /transl_table=11
                     /product="remnant of a transposase"
                     /protein_id="YP_976164.1"
                     /db_xref="GI:121635941"
                     /db_xref="GeneID:4696701"
                     /translation="MLARHFGAGRKAHSRAVATLKADIQAWHPAGIQTPKPRCESDVF
                     ARIGHTSHPSTRKSRVGPGASEAPLA"
     gene            63946..66261
                     /gene="bioF2"
                     /locus_tag="BCG_0063"
                     /db_xref="GeneID:4696691"
     CDS             63946..66261
                     /gene="bioF2"
                     /locus_tag="BCG_0063"
                     /EC_number="2.3.1.47"
                     /codon_start=1
                     /transl_table=11
                     /product="8-amino-7-oxononanoate synthase bioF2"
                     /protein_id="YP_976165.1"
                     /db_xref="GI:121635942"
                     /db_xref="GeneID:4696691"
                     /translation="MPTGLGYDFLRPVEDSGINDLKHYYFMADLADGQPLGRANLYSV
                     CFDLATTDRKLTPAWRTTIKRWFPGFMTFRFLECGLLTMVSNPLALRSDTDLERVLPV
                     LAGQMDQLAHDDGSDFLMIRDVDPEHYQRYLDILRPLGFRPALGFSRVDTTISWSSVE
                     EALGCLSHKRRLPLKTSLEFRERFGIEVEELDEYAEHAPVLARLWRNVKTEAKDYQRE
                     DLNPEFFAACSRHLHGRSRLWLFRYQGTPIAFFLNVWGADENYILLEWGIDRDFEHYR
                     KANLYRAALMLSLKDAISRDKRRMEMGITNYFTKLRIPGARVIPTIYFLRHSTDPVHT
                     ATLARMMMHNIQRPTLPDDMSEEFCRWEERIRLDQDGLPEHDIFRKIDRQHKYTGLKL
                     GGVYGFYPRFTGPQRSTVKAAELGEIVLLGTNSYLGLATHPEVVEASAEATRRYGTGC
                     SGSPLLNGTLDLHVSLEQELACFLGKPAAVLCSTGYQSNLAAISALCESGDMIIQDAL
                     NHRSLFDAARLSGADFTLYRHNDMDHLARVLRRTEGRRRIIVVDAVFSMEGTVADLAT
                     IAELADRHGCRVYVDESHALGVLGPDGRGASAALGVLARMDVVMGTFSKSFASVGGFI
                     AGDRPVVDYIRHNGSGHVFSASLPPAAAAATHAALRVSRREPDRRARVLAAAEYMATG
                     LARQGYQAEYHGTAIVPVILGNPTVAHAGYLRLMRSGVYVNPVAPPAVPEERSGFRTS
                     YLADHRQSDLDRALHVFAGLAEDLTPQGAAL"
     misc_feature    64489..64866
                     /gene="bioF2"
                     /locus_tag="BCG_0063"
                     /note="Acetyltransferase (GNAT) domain; Region:
                     Acetyltransf_6; pfam13480"
                     /db_xref="CDD:257804"
     misc_feature    65095..66225
                     /gene="bioF2"
                     /locus_tag="BCG_0063"
                     /note="7-keto-8-aminopelargonate synthetase and related
                     enzymes [Coenzyme metabolism]; Region: BioF; COG0156"
                     /db_xref="CDD:223234"
     misc_feature    65194..66216
                     /gene="bioF2"
                     /locus_tag="BCG_0063"
                     /note="Aspartate aminotransferase (AAT) superfamily (fold
                     type I) of pyridoxal phosphate (PLP)-dependent enzymes.
                     PLP combines with an alpha-amino acid to form a compound
                     called a Schiff base or aldimine intermediate, which
                     depending on the reaction, is the...; Region: AAT_I;
                     cl18945"
                     /db_xref="CDD:271826"
     misc_feature    order(65398..65403,65410..65412,65599..65601,65686..65688,
                     65695..65697,65779..65781,65788..65790)
                     /gene="bioF2"
                     /locus_tag="BCG_0063"
                     /note="pyridoxal 5'-phosphate binding pocket [chemical
                     binding]; other site"
                     /db_xref="CDD:99742"
     misc_feature    65788..65790
                     /gene="bioF2"
                     /locus_tag="BCG_0063"
                     /note="catalytic residue [active]"
                     /db_xref="CDD:99742"
     gene            66258..66521
                     /gene="acpA"
                     /locus_tag="BCG_0064"
                     /db_xref="GeneID:4695544"
     CDS             66258..66521
                     /gene="acpA"
                     /locus_tag="BCG_0064"
                     /standard_name="acpP"
                     /codon_start=1
                     /transl_table=11
                     /product="acyl carrier protein"
                     /protein_id="YP_976166.1"
                     /db_xref="GI:121635943"
                     /db_xref="GeneID:4695544"
                     /translation="MKEAINATIQRILRTDRGITANQVLVDDLGFDSLKLFQLITELE
                     DEFDIAISFRDAQNIKTVGDVYTSVAVWFPETAKPAPLGKGTA"
     misc_feature    66258..66464
                     /gene="acpA"
                     /locus_tag="BCG_0064"
                     /note="Acyl carrier protein [Lipid metabolism / Secondary
                     metabolites biosynthesis, transport, and catabolism];
                     Region: AcpP; COG0236"
                     /db_xref="CDD:223314"
     gene            66518..66913
                     /locus_tag="BCG_0065"
                     /db_xref="GeneID:4695773"
     CDS             66518..66913
                     /locus_tag="BCG_0065"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_976167.1"
                     /db_xref="GI:121635944"
                     /db_xref="GeneID:4695773"
                     /translation="MTDDADLDLVRRTFAAFARGDLAELTQCFAPDVEQFVPGKHALA
                     GVFRGVDNVVACLGDTAAAADGTMTVTLEDVLSNTDGQVIAVYRLRASRAGKVLDQRE
                     AILVTVAGGRITRLSEFYADPAATESFWA"
     misc_feature    66518..66910
                     /locus_tag="BCG_0065"
                     /note="Ketosteroid isomerase-related protein [General
                     function prediction only]; Region: COG3631"
                     /db_xref="CDD:226158"
     gene            66910..68598
                     /gene="fadD34"
                     /locus_tag="BCG_0066"
                     /db_xref="GeneID:4697408"
     CDS             66910..68598
                     /gene="fadD34"
                     /locus_tag="BCG_0066"
                     /EC_number="6.2.1.-"
                     /codon_start=1
                     /transl_table=11
                     /product="fatty-acid-CoA ligase"
                     /protein_id="YP_976168.1"
                     /db_xref="GI:121635945"
                     /db_xref="GeneID:4697408"
                     /translation="MTAALLSPAIAWQQISACTDRTLTITCEDSEVISYQDLIARAAA
                     CIPPLRRLDLKRGEPVLITAHTNLEFLSCFLGLMLHGAVPVPIPPREALKTTERFMTR
                     LGPLLRHHRVLICTPAEHDEIRAAASTDCQISRFTALAEAGDEQFGRATAQQLADTAT
                     ADWPLCTLDDDAYVQYTSGSTAAPRGVVITYRNLLSNMRAMAVGSQFQHGDVMGSWLP
                     LHHDMGLVGSLFAALFNSVSAVFTTPHRFLYDPLGFLRLLTSSGATHTFMPNFALEWL
                     INAYHRRGADIEGIDLHKMRRLIIASEPVHAEGMRRFAATFAGVGLAPTALGSGYGLA
                     EATVAVSMSAPNTGFRTETHAAAEVVTGGRVLPGYEVRIDAAPGARAGTIKLRGDSVA
                     AKAYVGGKKLDALDEEGFCDTHDLGFLVDDEIVILGRQDEVFIVHGENRFPYDIEFII
                     RGESEQHRTKVACFGVNERVVVVLESPLDSIIDKAEADRLRCQVVAATGLQLDELITV
                     RRGAIPTTTSGKLKRRAVAQAYRDGTLPRLATHAWTADPDSAPKTTRSSLEGAH"
     misc_feature    66910..68526
                     /gene="fadD34"
                     /locus_tag="BCG_0066"
                     /note="Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases
                     II [Lipid metabolism / Secondary metabolites biosynthesis,
                     transport, and catabolism]; Region: CaiC; COG0318"
                     /db_xref="CDD:223395"
     misc_feature    66946..68505
                     /gene="fadD34"
                     /locus_tag="BCG_0066"
                     /note="Fatty acyl-AMP ligase (FAAL); Region: FAAL;
                     cd05931"
                     /db_xref="CDD:213297"
     misc_feature    order(67429..67431,67438..67455,67459..67464)
                     /gene="fadD34"
                     /locus_tag="BCG_0066"
                     /note="acyl-activating enzyme (AAE) consensus motif; other
                     site"
                     /db_xref="CDD:213297"
     misc_feature    order(67510..67512,67570..67578,67804..67806,67813..67824,
                     67897..67911,67924..67926,67993..67995,68152..68154,
                     68185..68187,68194..68196)
                     /gene="fadD34"
                     /locus_tag="BCG_0066"
                     /note="active site"
                     /db_xref="CDD:213297"
     gene            complement(68799..69479)
                     /locus_tag="BCG_0067c"
                     /db_xref="GeneID:4699133"
     CDS             complement(68799..69479)
                     /locus_tag="BCG_0067c"
                     /note="Differs from Mb0037c and Rv0036c by 1aa, L186P, and
                     at C-terminal end due to frameshift resulting from 1 bp
                     deletion at position equivalent to Mycobacterium
                     tuberculosis H37Rv2, 39228-39228, after codon 202"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_976169.1"
                     /db_xref="GI:121635946"
                     /db_xref="GeneID:4699133"
                     /translation="MADPGPFVADLRAESDDLDALVAHLPADRWADPTPAPGWTIAHQ
                     IGHLLWTDRVALTAVTDEAGFAELMTAAAANPAGFVDDAATELAAVSPAELLTDWRVT
                     RGRLHEELLAVPDGRKLAWFGPPMSAASMATARLMETWAHGLDVADALGVIRPATQRL
                     RSIAHLGVRTRDYAFIVNNLTPPAELFLVELRGPSGDTWSWGHPMRPSGSPGPPRTSA
                     SWSPSGAR"
     misc_feature    complement(69039..69449)
                     /locus_tag="BCG_0067c"
                     /note="Mycothiol maleylpyruvate isomerase N-terminal
                     domain; Region: MDMPI_N; pfam11716"
                     /db_xref="CDD:256569"
     gene            complement(69527..70852)
                     /locus_tag="BCG_0068c"
                     /db_xref="GeneID:4697953"
     CDS             complement(69527..70852)
                     /locus_tag="BCG_0068c"
                     /codon_start=1
                     /transl_table=11
                     /product="integral membrane protein"
                     /protein_id="YP_976170.1"
                     /db_xref="GI:121635947"
                     /db_xref="GeneID:4697953"
                     /translation="MPRVEVGLVIHSRMHARAPVDVWRSVRSLPDFWRLLQVRVASQF
                     GDGLFQAGLAGALLFNPDRAADPMAIAGAFAVLFLPYSLLGPFAGALMDRWDRRWVLV
                     GANTGRLALIAGVGTILAVGAGDVPLLVGALVANGLARFVASGLSAALPHVVPREQVV
                     TMNSVAIASGAVSAFLGANFMLLPRWLLGSGDEGASAIVFLVAIPVSIALLWSLRFGP
                     RVLGPDDTERAIHGSAVYAVVTGWLHGARTVVQLPTVAAGLSGLAAHRMVVGINSLLI
                     LLLVRHVTARAVGGLGTALLFFAATGLGAFLANVLTPTAIRRWGRYATANGALAAAAT
                     IQVAAAGLLVPVMVVCGFLLGVAGQVVKLCADSAMQMDVDDALRGHVFAVQDALFWVS
                     YILSITVAAALIPEHGHAPVFVLFGSAIYLAGLVVHTIVGRRGQPVIGR"
     misc_feature    complement(69638..70759)
                     /locus_tag="BCG_0068c"
                     /note="H+ Antiporter protein; Region: 2A0121; TIGR00900"
                     /db_xref="CDD:162098"
     misc_feature    complement(69560..70669)
                     /locus_tag="BCG_0068c"
                     /note="The Major Facilitator Superfamily (MFS) is a large
                     and diverse group of secondary transporters that includes
                     uniporters, symporters, and antiporters. MFS proteins
                     facilitate the transport across cytoplasmic or internal
                     membranes of a variety of...; Region: MFS; cd06174"
                     /db_xref="CDD:119392"
     misc_feature    complement(order(69674..69676,69683..69688,69695..69700,
                     69707..69712,69743..69745,69752..69757,69767..69769,
                     69776..69781,69788..69790,69926..69928,69938..69940,
                     69947..69949,69959..69961,69971..69973,70013..70015,
                     70022..70027,70034..70039,70046..70048,70331..70333,
                     70349..70354,70361..70366,70400..70402,70409..70414,
                     70421..70426,70433..70435,70586..70591,70595..70600,
                     70610..70612,70619..70624,70631..70633))
                     /locus_tag="BCG_0068c"
                     /note="putative substrate translocation pore; other site"
                     /db_xref="CDD:119392"
     gene            70954..71562
                     /locus_tag="BCG_0069"
                     /db_xref="GeneID:4696034"
     CDS             70954..71562
                     /locus_tag="BCG_0069"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_976171.1"
                     /db_xref="GI:121635948"
                     /db_xref="GeneID:4696034"
                     /translation="MVAPHEDPEDHVAPAAQRVRAGTLLLANTDLLEPTFRRSVIYIV
                     EHNDGGTLGVVLNRPSETAVYNVLPQWAKLAAKPKTMFIGGPVKRDAALCLAVLRVGA
                     DPEGVPGLRHVAGRLVMVDLDADPEVLAAAVEGVRIYAGYSGWTIGQLEGEIERDDWI
                     VLSALPSDVLVGPRADLWGQVLRRQPLPLSLLATHPIDLSRN"
     misc_feature    70990..71550
                     /locus_tag="BCG_0069"
                     /note="hypothetical protein; Validated; Region: PRK00228"
                     /db_xref="CDD:234694"
     gene            complement(71654..72001)
                     /locus_tag="BCG_0070c"
                     /db_xref="GeneID:4699368"
     CDS             complement(71654..72001)
                     /locus_tag="BCG_0070c"
                     /note="Differs from Rv0039c by 1aa, F24C"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_976172.1"
                     /db_xref="GI:121635949"
                     /db_xref="GeneID:4699368"
                     /translation="MFLAGVLCMCAAAASALFGSWSLFHTPTADPTALALRAMAPTQL
                     AAAVMLAAGGVVAVAAPGHTALMVVIVCIAGAVGTLAAGSWQSAQYALRRETASPTAN
                     CVGSCAVCTQACH"
     gene            complement(72083..73015)
                     /gene="mtc28"
                     /locus_tag="BCG_0071c"
                     /db_xref="GeneID:4697254"
     CDS             complement(72083..73015)
                     /gene="mtc28"
                     /locus_tag="BCG_0071c"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_976173.1"
                     /db_xref="GI:121635950"
                     /db_xref="GeneID:4697254"
                     /translation="MIQIARTWRVFAGGMATGFIGVVLVTAGKASADPLLPPPPIPAP
                     VSAPATVPPVQNLTALPGGSSNRFSPAPAPAPIASPIPVGAPGSTAVPPLPPPVTPAI
                     SGTLRDHLREKGVKLEAQRPHGFKALDITLPMPPRWTQVPDPNVPDAFVVIADRLGNS
                     VYTSNAQLVVYRLIGDFDPAEAITHGYIDSQKLLAWQTTNASMANFDGFPSSIIEGTY
                     RENDMTLNTSRRHVIATSGADKYLVSLSVTTALSQAVTDGPATDAIVNGFQVVAHAAP
                     AQAPAPAPGSAPVGLPGQAPGYPPAGTLTPVPPR"
     misc_feature    complement(72206..72709)
                     /gene="mtc28"
                     /locus_tag="BCG_0071c"
                     /note="Probable lipoprotein LpqN; Region: Lpp-LpqN;
                     pfam10738"
                     /db_xref="CDD:256148"
     gene            73212..76121
                     /gene="leuS"
                     /locus_tag="BCG_0072"
                     /db_xref="GeneID:4697737"
     CDS             73212..76121
                     /gene="leuS"
                     /locus_tag="BCG_0072"
                     /EC_number="6.1.1.4"
                     /note="leucine--tRNA ligase; LeuRS; class-I aminoacyl-tRNA
                     synthetase; charges leucine by linking carboxyl group to
                     alpha-phosphate of ATP and then transfers
                     aminoacyl-adenylate to its tRNA; due to the large number
                     of codons that tRNA(Leu) recognizes, the leucyl-tRNA
                     synthetase does not recognize the anticodon loop of the
                     tRNA, but instead recognition is dependent on a conserved
                     discriminator base A37 and a long arm; an editing domain
                     hydrolyzes misformed products; in Methanothermobacter
                     thermautotrophicus this enzyme associates with prolyl-tRNA
                     synthetase"
                     /codon_start=1
                     /transl_table=11
                     /product="leucyl-tRNA synthetase"
                     /protein_id="YP_976174.1"
                     /db_xref="GI:121635951"
                     /db_xref="GeneID:4697737"
                     /translation="MTESPTAGPGGVPRADDADSDVPRYRYTAELAARLERTWQENWA
                     RLGTFNVPNPVGSLAPPDGAAVPDDKLFVQDMFPYPSGEGLHVGHPLGYIATDVYARY
                     FRMVGRNVLHALGFDAFGLPAEQYAVQTGTHPRTRTEANVVNFRRQLGRLGFGHDSRR
                     SFSTTDVDFYRWTQWIFLQIYNAWFDTTANKARPISELVAEFESGARCLDGGRDWAKL
                     TAGERADVIDEYRLVYRADSLVNWCPGLGTVLANEEVTADGRSDRGNFPVFRKRLRQW
                     MMRITAYADRLLDDLDVLDWPEQVKTMQRNWIGRSTGAVALFSARAASDDGFEVDIEV
                     FTTRPDTLFGATYLVLAPEHDLVDELVAASWPAGVNPLWTYGGGTPGEAIAAYRRAIA
                     AKSDLERQESREKTGVFLGSYAINPANGEPVPIFIADYVLAGYGTGAIMAVPGHDQRD
                     WDFARAFGLPIVEVIAGGNISESAYTGDGILVNSDYLNGMSVPAAKRAIVDRLESAGR
                     GRARIEFKLRDWLFARQRYWGEPFPIVYDSDGRPHALDEAALPVELPDVPDYSPVLFD
                     PDDADSEPSPPLAKATEWVHVDLDLGDGLKPYSRDTNVMPQWAGSSWYELRYTDPHNS
                     ERFCAKENEAYWMGPRPAEHGPDDPGGVDLYVGGAEHAVLHLLYSRFWHKVLYDLGHV
                     SSREPYRRLVNQGYIQAYAYTDARGSYVPAEQVIERGDRFVYPGPDGEVEVFQEFGKI
                     GKSLKNSVSPDEICDAYGADTLRVYEMSMGPLEASRPWATKDVVGAYRFLQRVWRLVV
                     DEHTGETRVADGVELDIDTLRALHRTIVGVSEDFAALRNNTATAKLIEYTNHLTKKHR
                     DAVPRAAVEPLVQMLAPLAPHIAEELWLRLGNTTSLAHGPFPKADAAYLVDETVEYPV
                     QVNGKVRGRVVVAADTDEETLKAAVLTDEKVQAFLAGATPRKVIVVAGRLVNLVI"
     misc_feature    73287..76118
                     /gene="leuS"
                     /locus_tag="BCG_0072"
                     /note="leucyl-tRNA synthetase; Validated; Region: leuS;
                     PRK00390"
                     /db_xref="CDD:234743"
     misc_feature    73419..>74138
                     /gene="leuS"
                     /locus_tag="BCG_0072"
                     /note="nucleotidyl transferase superfamily; Region:
                     nt_trans; cl00015"
                     /db_xref="CDD:271408"
     misc_feature    73467..73478
                     /gene="leuS"
                     /locus_tag="BCG_0072"
                     /note="active site"
                     /db_xref="CDD:173912"
     misc_feature    73467..73478
                     /gene="leuS"
                     /locus_tag="BCG_0072"
                     /note="HIGH motif; other site"
                     /db_xref="CDD:173912"
     misc_feature    order(73467..73469,73476..73478)
                     /gene="leuS"
                     /locus_tag="BCG_0072"
                     /note="nucleotide binding site [chemical binding]; other
                     site"
                     /db_xref="CDD:173912"
     misc_feature    74124..74723
                     /gene="leuS"
                     /locus_tag="BCG_0072"
                     /note="Leucyl-tRNA synthetase, Domain 2; Region:
                     tRNA-synt_1_2; pfam13603"
                     /db_xref="CDD:257918"
     misc_feature    <74760..75545
                     /gene="leuS"
                     /locus_tag="BCG_0072"
                     /note="nucleotidyl transferase superfamily; Region:
                     nt_trans; cl00015"
                     /db_xref="CDD:271408"
     misc_feature    75432..75443
                     /gene="leuS"
                     /locus_tag="BCG_0072"
                     /note="active site"
                     /db_xref="CDD:173912"
     misc_feature    75432..75443
                     /gene="leuS"
                     /locus_tag="BCG_0072"
                     /note="KMSKS motif; other site"
                     /db_xref="CDD:173912"
     misc_feature    75543..75869
                     /gene="leuS"
                     /locus_tag="BCG_0072"
                     /note="Anticodon-binding domain of bacterial and
                     eukaryotic mitochondrial leucyl tRNA synthetases; Region:
                     Anticodon_Ia_Leu_BEm; cd07958"
                     /db_xref="CDD:153412"
     misc_feature    order(75552..75554,75561..75566,75573..75575,75585..75587,
                     75723..75725,75735..75737,75744..75749,75756..75758,
                     75765..75767)
                     /gene="leuS"
                     /locus_tag="BCG_0072"
                     /note="tRNA binding surface [nucleotide binding]; other
                     site"
                     /db_xref="CDD:153412"
     gene            complement(76231..76857)
                     /locus_tag="BCG_0073c"
                     /db_xref="GeneID:4697485"
     CDS             complement(76231..76857)
                     /locus_tag="BCG_0073c"
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulatory protein
                     (marR-family)"
                     /protein_id="YP_976175.1"
                     /db_xref="GI:121635952"
                     /db_xref="GeneID:4697485"
                     /translation="MSVVRSIGKKMQRISGPNALAVKGRPTQVYGHTHVRLDCRFMAD
                     SEFTAPEVTQLAEGLHRALSKLISMLRRGDPNGAAAGDLTLAQLSILVTLLDQGPIRM
                     TDLAAHERVRTPTTTVAIRRLEKIGLVKRSRDPSDLRAVLVDITPQGRAVHGESLANR
                     RAALAALLSQLPRSDLETLRKALAPLERLASGEPASGPASNSPARKRA"
     misc_feature    complement(76294..76653)
                     /locus_tag="BCG_0073c"
                     /note="Transcriptional regulators [Transcription]; Region:
                     MarR; COG1846"
                     /db_xref="CDD:224759"
     misc_feature    complement(<76399..76614)
                     /locus_tag="BCG_0073c"
                     /note="Arsenical Resistance Operon Repressor and similar
                     prokaryotic, metal regulated homodimeric repressors. ARSR
                     subfamily of helix-turn-helix bacterial transcription
                     regulatory proteins (winged helix topology). Includes
                     several proteins that appear to...; Region: HTH_ARSR;
                     cl17220"
                     /db_xref="CDD:266564"
     gene            complement(77016..77750)
                     /locus_tag="BCG_0074c"
                     /db_xref="GeneID:4695352"
     CDS             complement(77016..77750)
                     /locus_tag="BCG_0074c"
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="YP_976176.1"
                     /db_xref="GI:121635953"
                     /db_xref="GeneID:4695352"
                     /translation="MPKKYGVKEKDQVVAHILNLLLTGKLRSGDRVDRNEIAHGLGVS
                     RVPIQEALVQLEHDGIVSTRYHRGAFIERFDVATILEHHELDGLLNGIASARAAANPT
                     PRILGQLDAVMRSLRNSKESRAFAECVWEYRRTVNDEYAGPRLHATIRASQNLIPRVF
                     WMTYQNSRDDVLPFYEEENAAIHRREPEAARAACIGRSELMAQTMLAELFRRRVLVPP
                     EGACPGPFGAPIPGFARSYQPSSPVP"
     misc_feature    complement(77076..77723)
                     /locus_tag="BCG_0074c"
                     /note="Transcriptional regulators [Transcription]; Region:
                     GntR; COG1802"
                     /db_xref="CDD:224715"
     misc_feature    complement(77538..77720)
                     /locus_tag="BCG_0074c"
                     /note="Winged helix-turn-helix (WHTH) DNA-binding domain
                     of the GntR family of transcriptional regulators; Region:
                     WHTH_GntR; cd07377"
                     /db_xref="CDD:153418"
     misc_feature    complement(order(77544..77555,77559..77564,77592..77594,
                     77601..77606,77610..77624,77646..77648,77652..77654))
                     /locus_tag="BCG_0074c"
                     /note="DNA-binding site [nucleotide binding]; DNA binding
                     site"
                     /db_xref="CDD:153418"
     gene            complement(77883..78677)
                     /locus_tag="BCG_0075c"
                     /db_xref="GeneID:4697694"
     CDS             complement(77883..78677)
                     /locus_tag="BCG_0075c"
                     /EC_number="1.-.-.-"
                     /codon_start=1
                     /transl_table=11
                     /product="oxidoreductase"
                     /protein_id="YP_976177.1"
                     /db_xref="GI:121635954"
                     /db_xref="GeneID:4697694"
                     /translation="MTSLVRPDLPVRIGVQLQPQHAPHYRAVRDAVRRCEDIGVDIAF
                     TWDHFFPLYGDPDGPHFECWTVLGAWAEQTSHIEIGALVTCNSYRNPELLADMARTVD
                     HISGGRLILGIGSGWKQKDYDEYGYRFGTAGSRLDDLAAALPRIKARLGKLNPPPTRD
                     IPVLIGGGGERKTLRLVAEYADIWHSFTAGDSYLAKSAVLSTHCSTVGRNPATIERSA
                     AVDGGGLIASAEALAGLGVTLLTVGCDGPDYDLSAAAALCRWRDGR"
     misc_feature    complement(<78327..78503)
                     /locus_tag="BCG_0075c"
                     /note="Flavin-utilizing monoxygenases; Region:
                     Flavin_utilizing_monoxygenases; cl19096"
                     /db_xref="CDD:271834"
     misc_feature    complement(<78081..78383)
                     /locus_tag="BCG_0075c"
                     /note="N5,N10-methylenetetrahydromethanopterin reductase
                     (Mer) catalyzes the reduction of
                     N5,N10-methylenetetrahydromethanopterin with reduced
                     coenzyme F420 to N5-methyltetrahydromethanopterin and
                     oxidized coenzyme F420; Region:
                     Tetrahydromethanopterin_reductase; cd01097"
                     /db_xref="CDD:238530"
     gene            complement(78693..79589)
                     /locus_tag="BCG_0076c"
                     /db_xref="GeneID:4697521"
     CDS             complement(78693..79589)
                     /locus_tag="BCG_0076c"
                     /EC_number="3.-.-.-"
                     /codon_start=1
                     /transl_table=11
                     /product="hydrolase"
                     /protein_id="YP_976178.1"
                     /db_xref="GI:121635955"
                     /db_xref="GeneID:4697521"
                     /translation="MLSDDELTGLDEFALLAENAEQAGVNGPLPEVERVQAGAISALR
                     WGGSAPRVIFLHGGGQNAHTWDTVIVGLGEPALAVDLPGHGHSAWREDGNYSPQLNSE
                     TLAPVLRELAPGAEFVVGMSLGGLTAIRLAAMAPDLVGELVLVDVTPSALQRHAELTA
                     EQRGTVALMHGEREFPSFQAMLDLTIAAAPHRDVKSLRRGVFHNSRRLDNGNWVWRYD
                     AIRTFGDFAGLWDDVDALSAPITLVRGGSSGFVTDQDTAELHRRATHFRGVHIVEKSG
                     HSVQSDQPRALIEIVRGVLDTR"
     misc_feature    complement(78720..79436)
                     /locus_tag="BCG_0076c"
                     /note="Alpha/beta hydrolase family; Region: Abhydrolase_6;
                     pfam12697"
                     /db_xref="CDD:257231"
     misc_feature    complement(78699..79367)
                     /locus_tag="BCG_0076c"
                     /note="Esterases and lipases (includes fungal lipases,
                     cholinesterases, etc.)  These enzymes act on carboxylic
                     esters (EC: 3.1.1.-). The catalytic apparatus involves
                     three residues (catalytic triad): a serine, a glutamate or
                     aspartate and a histidine.These...; Region:
                     Esterase_lipase; cl21494"
                     /db_xref="CDD:271914"
     gene            complement(79671..80774)
                     /gene="ino1"
                     /locus_tag="BCG_0077c"
                     /db_xref="GeneID:4696669"
     CDS             complement(79671..80774)
                     /gene="ino1"
                     /locus_tag="BCG_0077c"
                     /EC_number="5.5.1.4"
                     /standard_name="tbINO"
                     /note="Differs from Mb0047c by 1aa, T120I, and from
                     Rv0046c by 2aa, T120I, G190R"
                     /codon_start=1
                     /transl_table=11
                     /product="myo-inositol-1-phosphate synthase INO1"
                     /protein_id="YP_976179.1"
                     /db_xref="GI:121635956"
                     /db_xref="GeneID:4696669"
                     /translation="MSEHQSLPAPEASTEVRVAIVGVGNCASSLVQGVEYYYNADDTS
                     TVPGLMHVRFGPYHVRDVKFVAAFDVDAKKVGFDLSDAIFASENNTIKIADVAPTNVI
                     VQRGPTLDGIGKYYADTTELSDAEPVDVVQALKEAKVDVLVSYLPVGSEEADKFYAQC
                     AIDAGVAFVNALPVFIASDPVWAKKFTDAGVPIVGDDIKSQVGATITHRVLAKLFEDR
                     GVQLDRTMQLNVGGNMDFLNMLERERLESKKISKTQAVTSNLKREFKTKDVHIGPSDH
                     VGWLDDRKWAYVRLEGRAFGDVPLNLEYKLEVWDSPNSAGVIIDAVRAAKIAKDRGIG
                     GPVIPASAYLMKSPPEQLPDDIARAQLEEFIIG"
     misc_feature    complement(79680..80729)
                     /gene="ino1"
                     /locus_tag="BCG_0077c"
                     /note="Myo-inositol-1-phosphate synthase; Region:
                     NAD_binding_5; cl00554"
                     /db_xref="CDD:260495"
     gene            complement(80835..81377)
                     /locus_tag="BCG_0078c"
                     /db_xref="GeneID:4697433"
     CDS             complement(80835..81377)
                     /locus_tag="BCG_0078c"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_976180.1"
                     /db_xref="GI:121635957"
                     /db_xref="GeneID:4697433"
                     /translation="MLELAILGLLIESPMHGYELRKRLTGLLGAFRAFSYGSLYPALR
                     RMQADGLIAENAAPAGTPVRRARRVYQLTDKGRRRFGELVADTGPHNYTDDGFGVHLA
                     FFNRTPAEARMRILEGRRRQVEERREGLREAVARASSSFDRYTRQLHQLGLESSEREV
                     KWLNELIAAERAAPNPAEQT"
     misc_feature    complement(81132..81362)
                     /locus_tag="BCG_0078c"
                     /note="Transcriptional regulator PadR-like family; Region:
                     PadR; pfam03551"
                     /db_xref="CDD:252023"
     gene            complement(81478..82347)
                     /locus_tag="BCG_0079c"
                     /db_xref="GeneID:4698581"
     CDS             complement(81478..82347)
                     /locus_tag="BCG_0079c"
                     /note="Differs from Rv0048c by 1aa, A250V"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_976181.1"
                     /db_xref="GI:121635958"
                     /db_xref="GeneID:4698581"
                     /translation="MAKWLGAPLARGVSTATRAKDSDRQDACRILDDALRDGELSMEE
                     HRERVSAATKAVTLGDLQRLVADLQVESAPAQMPALKSRAKRTELGLLAAAFVASVLL
                     GVGIGWGVYGNTRSPLDFTSDPGAKPDGIAPVVLTPPRQLHSLGGLTGLLEQTRKRFG
                     DTMGYRLVIYPEYASLDRVDPADDRRVLAYTYRGGWGDATSSAKSIADVSVVDLSKFD
                     AKTAVSIMRGAPETLGLKQSDVKSMYLIVEPAKDPTTPAALSLSLYVSSDYGGGYLVF
                     AGDGTIKHVSYPS"
     misc_feature    complement(82141..82299)
                     /locus_tag="BCG_0079c"
                     /note="Domain of unknown function (DUF1707); Region:
                     DUF1707; pfam08044"
                     /db_xref="CDD:149239"
     gene            82481..82894
                     /locus_tag="BCG_0080"
                     /db_xref="GeneID:4696521"
     CDS             82481..82894
                     /locus_tag="BCG_0080"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_976182.1"
                     /db_xref="GI:121635959"
                     /db_xref="GeneID:4696521"
                     /translation="MDYTLRRRSLLAEVYSGRTGVSEVCDANPYLLRAAKFHGKPSRV
                     ICPICRKEQLTLVSWVFGEHLGAVSGSARTAEELILLATRFSEFAVHVVEVCRTCSWN
                     HLVKSYVLGAARPARPPRGSGGTRTARNGARTASE"
     gene            83313..85358
                     /gene="ponA1"
                     /locus_tag="BCG_0081"
                     /db_xref="GeneID:4696779"
     CDS             83313..85358
                     /gene="ponA1"
                     /locus_tag="BCG_0081"
                     /EC_number="2.4.2.-"
                     /EC_number="3.4.-.-"
                     /note="In Mycobacterium bovis BCG Pasteur, insertion of 3
                     codons after position 632 leads to a slightly longer
                     product compared to its homologs in Mycobacterium
                     tuberculosis strain H37Rv (681 aa versus 678 aa) and
                     Mycobacterium bovis AF2122/97 (681 aa versus 680 aa). In
                     addition, differs from Rv0050 by 1aa, L6P"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional penicillin-binding protein 1A/1B
                     PONA1"
                     /protein_id="YP_976183.1"
                     /db_xref="GI:121635960"
                     /db_xref="GeneID:4696779"
                     /translation="MVILLLMVTFTMAYLIVDVPKPGDIRTNQVSTILASDGSEIAKI
                     VPPEGNRVDVNLSQVPMHVRQAVIAAEDRNFYSNPGFSFTGFARAVKNNLFGGDLQGG
                     STITQQYVKNALVGSAQHGWSGLMRKAKELVIATKMSGEWSKDDVLQAYLNIIYFGRG
                     AYGISAASKAYFDKPVEQLTVAEGALLAALIRRPSTLDPAVDPEGAHARWNWVLDGMV
                     ETKALSPNDRAAQVFPETVPPDLARAENQTKGPNGLIERQVTRELLELFNIDEQTLNT
                     QGLVVTTTIDPQAQRAAEKAVAKYLDGQDPDMRAAVVSIDPHNGAVRAYYGGDNANGF
                     DFAQAGLQTGSSFKVFALVAALEQGIGLGYQVDSSPLTVDGIKITNVEGEGCGTCNIA
                     EALKMSLNTSYYRLMLKLNGGPQAVADAAHQAGIASSFPGVAHTLSEDGKGGPPNNGI
                     VLGQYQTRVIDMASAYATLAASGIYHPPHFVQKVVSANGQVLFDASTADNTGDQRIPK
                     AVADNVTAAMEPIAGYSRGHNLAGGRDSAAKTGTTQFGDTTANKDAWMVGYTPSLSTA
                     VWVGTVKGDEPLVTASGAAIYGSGLPSDIWKATMDGALKGTSNETFPKPTEVGGYAGV
                     PPPPPPPPPSEVPPSETVIQPTVEIAPGITIPIGPPTTITLAPPPPAPPAATPTPPP"
     misc_feature    83421..83966
                     /gene="ponA1"
                     /locus_tag="BCG_0081"
                     /note="Transglycosylase; Region: Transgly; pfam00912"
                     /db_xref="CDD:250219"
     misc_feature    83460..85130
                     /gene="ponA1"
                     /locus_tag="BCG_0081"
                     /note="penicillin-binding protein, 1A family; Region:
                     PBP_1a_fam; TIGR02074"
                     /db_xref="CDD:233710"
     misc_feature    84240..85115
                     /gene="ponA1"
                     /locus_tag="BCG_0081"
                     /note="Penicillin binding protein transpeptidase domain;
                     Region: Transpeptidase; pfam00905"
                     /db_xref="CDD:250215"
     gene            85355..87037
                     /locus_tag="BCG_0082"
                     /db_xref="GeneID:4696279"
     CDS             85355..87037
                     /locus_tag="BCG_0082"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_976184.1"
                     /db_xref="GI:121635961"
                     /db_xref="GeneID:4696279"
                     /translation="MTGALSQSSNISPLPLAADLRSADNRDCPSRTDVLGAALANVVG
                     GPVGRHALIGRTRLMTPLRVMFAIALVFLALGWSTKAACLQSTGTGPGDQRVANWDNQ
                     RAYYQLCYSDTVPLYGAELLSQGKFPYKSSWIETDSNGTPQLRYDGQIAVRYMEYPVL
                     TGIYQYLSMAIAKTYTALSKVAPLPVVAEVVMFFNVAAFGLALAWLTTVWATSGLAGR
                     RIWDAALVAASPLVIFQIFTNFDALATGLATSGLLAWARRRPVLAGVLIGLGSAAKLY
                     PLLFLYPLLLLGIRAGRLNALARTMAAAAATWLLVNLPVMLLFPRGWSEFFRLNTRRG
                     DDMDSLYNVVKSFTGWRGFDPTLGFWEPPLVLNTVVTLLFVLCCAAIAYIALTAPHRP
                     RVAQLTFLTVASFLLVNKVWSPQFSLWLVPLAVLALPHRRILLAWMTIDALVWVPRMY
                     YLYGNPSRSLPEQWFTTTVLLRDIAVMVLCGLVVWQIYRPGRDLVRTGGPGALPACGG
                     VDDPVGGVFANAADAPPGRLPSWLRPRLGDEHARERTPDAGRDRTFSGQHRA"
     misc_feature    85412..87034
                     /locus_tag="BCG_0082"
                     /note="Predicted integral membrane protein [Function
                     unknown]; Region: COG5650"
                     /db_xref="CDD:227937"
     gene            87069..87632
                     /locus_tag="BCG_0083"
                     /db_xref="GeneID:4697704"
     CDS             87069..87632
                     /locus_tag="BCG_0083"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_976185.1"
                     /db_xref="GI:121635962"
                     /db_xref="GeneID:4697704"
                     /translation="MPSFDVVFVGHRRGEVRSDNAMLGLLCDAAFDELTRPDVVIFPG
                     GIGTRTLIHDQTVLDWVREAHRHTLLTTSVCTGGLVLAAAGLLNGLTATTHWRVQDLF
                     NSLGARYVPQRVVEHLPERVITAAGVSSGIDMGLRLVELLVSREAAEASQLMIEYDPQ
                     PPVDAGSLAKASPATHRLALEFYQHRL"
     misc_feature    87072..87542
                     /locus_tag="BCG_0083"
                     /note="Type 1 glutamine amidotransferase (GATase1)-like
                     domain found in a subgroup of proteins similar to PfpI
                     from Pyrococcus furiosus; Region: GATase1_PfpI_2; cd03139"
                     /db_xref="CDD:153233"
     misc_feature    87291..87293
                     /locus_tag="BCG_0083"
                     /note="conserved cys residue [active]"
                     /db_xref="CDD:153233"
     gene            87851..88141
                     /gene="rpsF"
                     /locus_tag="BCG_0084"
                     /db_xref="GeneID:4695848"
     CDS             87851..88141
                     /gene="rpsF"
                     /locus_tag="BCG_0084"
                     /note="binds cooperatively with S18 to the S15-16S
                     complex, allowing platform assembly to continue with S11
                     and S21"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S6"
                     /protein_id="YP_976186.1"
                     /db_xref="GI:121635963"
                     /db_xref="GeneID:4695848"
                     /translation="MRPYEIMVILDPTLDERTVAPSLETFLNVVRKDGGKVEKVDIWG
                     KRRLAYEIAKHAEGIYVVIDVKAAPATVSELDRQLSLNESVLRTKVMRTDKH"
     misc_feature    87851..88138
                     /gene="rpsF"
                     /locus_tag="BCG_0084"
                     /note="30S ribosomal protein S6; Reviewed; Region: rpsF;
                     PRK00453"
                     /db_xref="CDD:179034"
     gene            88245..88739
                     /gene="ssb"
                     /locus_tag="BCG_0085"
                     /db_xref="GeneID:4697300"
     CDS             88245..88739
                     /gene="ssb"
                     /locus_tag="BCG_0085"
                     /note="binds to single stranded DNA and may facilitate the
                     binding and interaction of other proteins to DNA"
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
                     /protein_id="YP_976187.1"
                     /db_xref="GI:121635964"
                     /db_xref="GeneID:4697300"
                     /translation="MAGDTTITIVGNLTADPELRFTPSGAAVANFTVASTPRIYDRQT
                     GEWKDGEALFLRCNIWREAAENVAESLTRGARVIVSGRLKQRSFETREGEKRTVIEVE
                     VDEIGPSLRYATAKVNKASRSGGFGSGSRPAPAQTSSASGDDPWGSAPASGSFGGGDD
                     EPPF"
     misc_feature    88248..88736
                     /gene="ssb"
                     /locus_tag="BCG_0085"
                     /note="Single-stranded DNA-binding protein [DNA
                     replication, recombination, and repair]; Region: Ssb;
                     COG0629"
                     /db_xref="CDD:223702"
     misc_feature    88263..88568
                     /gene="ssb"
                     /locus_tag="BCG_0085"
                     /note="SSB_OBF: A subfamily of OB folds similar to the OB
                     fold of ssDNA-binding protein (SSB). SSBs bind with high
                     affinity to ssDNA. They bind to and protect ssDNA
                     intermediates during DNA metabolic pathways. All bacterial
                     and eukaryotic SSBs studied to date...; Region: SSB_OBF;
                     cd04496"
                     /db_xref="CDD:239942"
     misc_feature    order(88263..88274,88347..88355,88401..88403,88407..88409,
                     88470..88472,88497..88499,88530..88532,88539..88541)
                     /gene="ssb"
                     /locus_tag="BCG_0085"
                     /note="dimer interface [polypeptide binding]; other site"
                     /db_xref="CDD:239942"
     misc_feature    order(88278..88286,88302..88304,88332..88334,88353..88358,
                     88395..88400,88404..88406,88410..88412,88416..88418,
                     88422..88424,88461..88466,88488..88490,88494..88496,
                     88500..88505,88542..88544,88548..88550)
                     /gene="ssb"
                     /locus_tag="BCG_0085"
                     /note="ssDNA binding site [nucleotide binding]; other
                     site"
                     /db_xref="CDD:239942"
     misc_feature    order(88470..88472,88476..88478,88482..88484,88563..88565)
                     /gene="ssb"
                     /locus_tag="BCG_0085"
                     /note="tetramer (dimer of dimers) interface [polypeptide
                     binding]; other site"
                     /db_xref="CDD:239942"
     gene            88781..89035
                     /gene="rpsR"
                     /locus_tag="BCG_0086"
                     /db_xref="GeneID:4695625"
     CDS             88781..89035
                     /gene="rpsR"
                     /locus_tag="BCG_0086"
                     /note="binds as a heterodimer with protein S6 to the
                     central domain of the 16S rRNA; helps stabilize the
                     platform of the 30S subunit"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S18"
                     /protein_id="YP_976188.1"
                     /db_xref="GI:121635965"
                     /db_xref="GeneID:4695625"
                     /translation="MAKSSKRRPAPEKPVKTRKCVFCAKKDQAIDYKDTALLRTYISE
                     RGKIRARRVTGNCVQHQRDIALAVKNAREVALLPFTSSVR"
     misc_feature    88793..89026
                     /gene="rpsR"
                     /locus_tag="BCG_0086"
                     /note="30S ribosomal protein S18; Reviewed; Region: rpsR;
                     PRK00391"
                     /db_xref="CDD:178997"
     gene            89068..89526
                     /gene="rplI"
                     /locus_tag="BCG_0087"
                     /db_xref="GeneID:4695807"
     CDS             89068..89526
                     /gene="rplI"
                     /locus_tag="BCG_0087"
                     /note="in Escherichia coli this protein is wrapped around
                     the base of the L1 stalk"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L9"
                     /protein_id="YP_976189.1"
                     /db_xref="GI:121635966"
                     /db_xref="GeneID:4695807"
                     /translation="MKLILTADVDHLGSIGDTVEVKDGYGRNFLLPRGLAIVASRGAQ
                     KQADEIRRARETKSVRDLEHANEIKAAIEALGPIALPVKTSADSGKLFGSVTAADVVA
                     AIKKAGGPNLDKRIVRLPKTHIKAVGTHFVSVHLHPEIDVEVSLDVVAQS"
     misc_feature    89068..89520
                     /gene="rplI"
                     /locus_tag="BCG_0087"
                     /note="50S ribosomal protein L9; Reviewed; Region: rplI;
                     PRK00137"
                     /db_xref="CDD:234659"
     misc_feature    89068..89205
                     /gene="rplI"
                     /locus_tag="BCG_0087"
                     /note="Ribosomal protein L9, N-terminal domain; Region:
                     Ribosomal_L9_N; pfam01281"
                     /db_xref="CDD:250502"
     misc_feature    89251..89520
                     /gene="rplI"
                     /locus_tag="BCG_0087"
                     /note="Ribosomal protein L9, C-terminal domain; Region:
                     Ribosomal_L9_C; pfam03948"
                     /db_xref="CDD:252268"
     gene            89555..90076
                     /locus_tag="BCG_0088"
                     /db_xref="GeneID:4695924"
     CDS             89555..90076
                     /locus_tag="BCG_0088"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_976190.1"
                     /db_xref="GI:121635967"
                     /db_xref="GeneID:4695924"
                     /translation="MPVVTAVGRRRGFAMPWVSTARSGAVMLANYSAGVCGRVSSPGL
                     NVRKMCLKANTPGAVTWLDTPKRFLSTQTASRCMAVNSSDVVTGRIDPQVLHTPLNTD
                     VDGYAHAMHSSINSGPLEYLPATFSVFPALGDVGDLGGGVGAATYALDRLSNMRSGAC
                     VGGGESPWRSLMT"
     gene            90055..92679
                     /gene="dnaB"
                     /locus_tag="BCG_0089"
                     /db_xref="GeneID:4696243"
     CDS             90055..92679
                     /gene="dnaB"
                     /locus_tag="BCG_0089"
                     /EC_number="3.6.1.-"
                     /note="unwinds double stranded DNA; these Mycobacterial
                     enzymes appear to contain inteins"
                     /codon_start=1
                     /transl_table=11
                     /product="replicative DNA helicase"
                     /protein_id="YP_976191.1"
                     /db_xref="GI:121635968"
                     /db_xref="GeneID:4696243"
                     /translation="MAVVDDLAPGMDSSPPSEDYGRQPPQDLAAEQSVLGGMLLSKDA
                     IADVLERLRPGDFYRPAHQNVYDAILDLYGRGEPADAVTVAAELDRRGLLRRIGGAPY
                     LHTLISTVPTAANAGYYASIVAEKALLRRLVEAGTRVVQYGYAGAEGADVAEVVDRAQ
                     AEIYDVADRRLSEDFVALEDLLQPTMDEIDAIASSGGLARGVATGFTELDEVTNGLHP
                     GQMVIVAARPGVGKSTLGLDFMRSCSIRHRMASVIFSLEMSKSEIVMRLLSAEAKIKL
                     SDMRSGRMSDDDWTRLARRMSEISEAPLFIDDSPNLTMMEIRAKARRLRQKANLKLIV
                     VDYLQLMTSGKKYESRQVEVSEFSRHLKLLAKELEVPVVAISQLNRGPEQRTDKKPML
                     ADLRESGCLTASTRILRADTGAEVAFGELMRSGERPMVWSLDERLRMVARPMINVFPS
                     GRKEVFRLRLASGREVEATGSHPFMKFEGWTPLAQLKVGDRIAAPRRVPEPIDTQRMP
                     ESELISLARMIGDGSCLKNQPIRYEPVDEANLAAVTVSAAHSDGAAIRDDYLAARVPS
                     LRPARQRLPRGRCTPIAAWLAGLGLFTKRSHEKCVPEAVFRAPNDQVALFLRHLWSAG
                     GSVRWDPTNGQGRVYYGSTSRRLIDDVAQLLLRVGIFSWITHAPKLGGHDSWRLHIHG
                     AKDQVRFLRHVGVHGAEAVAAQEMLRQLKGPVRNPNLDSAPKKVWAQVRNRLSAKQMM
                     DIQLHEPTMWKHSPSRSRPHRAEARIEDRAIHELARGDAYWDTVVEITSIGDQHVFDG
                     TVSGTHNFVANGISLHNSLEQDADVVILLHRPDAFDRDDPRGGEADFILAKHRNGPTK
                     TVTVAHQLHLSRFANMAR"
     misc_feature    90055..92676
                     /gene="dnaB"
                     /locus_tag="BCG_0089"
                     /note="replicative DNA helicase; Validated; Region:
                     PRK07773"
                     /db_xref="CDD:236093"
     misc_feature    90121..90429
                     /gene="dnaB"
                     /locus_tag="BCG_0089"
                     /note="DnaB-like helicase N terminal domain; Region: DnaB;
                     pfam00772"
                     /db_xref="CDD:250122"
     misc_feature    90673..>91251
                     /gene="dnaB"
                     /locus_tag="BCG_0089"
                     /note="DnaB helicase C terminal domain. The hexameric
                     helicase DnaB unwinds the DNA duplex at the  chromosome
                     replication fork. Although the mechanism by which DnaB
                     both couples ATP hydrolysis to translocation along DNA and
                     denatures the duplex is unknown, a...; Region: DnaB_C;
                     cd00984"
                     /db_xref="CDD:238484"
     misc_feature    90733..90753
                     /gene="dnaB"
                     /locus_tag="BCG_0089"
                     /note="Walker A motif; other site"
                     /db_xref="CDD:238484"
     misc_feature    order(90748..90753,91060..91062,91183..91185)
                     /gene="dnaB"
                     /locus_tag="BCG_0089"
                     /note="ATP binding site [chemical binding]; other site"
                     /db_xref="CDD:238484"
     misc_feature    91051..91062
                     /gene="dnaB"
                     /locus_tag="BCG_0089"
                     /note="Walker B motif; other site"
                     /db_xref="CDD:238484"
     misc_feature    order(91075..91080,91099..91107,91180..91206)
                     /gene="dnaB"
                     /locus_tag="BCG_0089"
                     /note="DNA binding loops [nucleotide binding]"
                     /db_xref="CDD:238484"
     misc_feature    91252..>91548
                     /gene="dnaB"
                     /locus_tag="BCG_0089"
                     /note="Hedgehog/Intein domain, found in Hedgehog proteins
                     as well as proteins which contain inteins and undergo
                     protein splicing (e.g. DnaB, RIR1-2, GyrA and Pol). In
                     protein splicing an intervening polypeptide sequence - the
                     intein - is excised from a protein; Region: Hint; cd00081"
                     /db_xref="CDD:238035"
     misc_feature    order(91252..91254,91459..91461,91468..91470)
                     /gene="dnaB"
                     /locus_tag="BCG_0089"
                     /note="thioester formation/cholesterol transfer; other
                     site"
                     /db_xref="CDD:238035"
     misc_feature    order(91252..91254,91468..91470)
                     /gene="dnaB"
                     /locus_tag="BCG_0089"
                     /note="protein-splicing catalytic site; other site"
                     /db_xref="CDD:238035"
     misc_feature    91894..92136
                     /gene="dnaB"
                     /locus_tag="BCG_0089"
                     /note="LAGLIDADG-like domain; Region: LAGLIDADG_3;
                     pfam14528"
                     /db_xref="CDD:258668"
     misc_feature    <92371..92499
                     /gene="dnaB"
                     /locus_tag="BCG_0089"
                     /note="Hedgehog/Intein domain, found in Hedgehog proteins
                     as well as proteins which contain inteins and undergo
                     protein splicing (e.g. DnaB, RIR1-2, GyrA and Pol). In
                     protein splicing an intervening polypeptide sequence - the
                     intein - is excised from a protein; Region: Hint; cd00081"
                     /db_xref="CDD:238035"
     misc_feature    92494..92499
                     /gene="dnaB"
                     /locus_tag="BCG_0089"
                     /note="protein-splicing catalytic site; other site"
                     /db_xref="CDD:238035"
     misc_feature    <92500..92646
                     /gene="dnaB"
                     /locus_tag="BCG_0089"
                     /note="ATP-binding cassette transporter nucleotide-binding
                     domain; Region: ABC_ATPase; cl21455"
                     /db_xref="CDD:271875"
     gene            92859..93551
                     /locus_tag="BCG_0090"
                     /db_xref="GeneID:4697423"
     CDS             92859..93551
                     /locus_tag="BCG_0090"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_976192.1"
                     /db_xref="GI:121635969"
                     /db_xref="GeneID:4697423"
                     /translation="MITRYKPESGFVARSGGPDRKRPHDWIVWHFTHADNLPGIITAG
                     RLLADSAVTPTTEVAYNPVKELRRHKVVAPDSRYPASMASDHVPFYIAARSPMLYVVC
                     KGHSGYSGGAGPLVHLGVALGDIIDADLTWCASDGNAAASYTKFSRQVDTLGTFVDFD
                     LLCQRQWHNTDDDPNRQSRRAAEILVYGHVPFELVSYVCCYNTETMTRVRTLLDPVGG
                     VRKYVIKPGMYY"
     misc_feature    92943..93548
                     /locus_tag="BCG_0090"
                     /note="Domain of unknown function (DUF4433); Region:
                     DUF4433; pfam14487"
                     /db_xref="CDD:258627"
     gene            93568..94626
                     /locus_tag="BCG_0091"
                     /db_xref="GeneID:4697073"
     CDS             93568..94626
                     /locus_tag="BCG_0091"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_976193.1"
                     /db_xref="GI:121635970"
                     /db_xref="GeneID:4697073"
                     /translation="MITYGSGDLLRADTEALVNTVNCVGVMGKGIALQFKRRYPEMFT
                     AYEKACKRGEVTIGKMFVVDTGQLDGPKHIINFPTKKHWRAPSKLAYIDAGLIDLIRV
                     IRELNIASVAVPPLGVGNGGLDWEDVEQRLVSAFQQLPDVDAVIYPPSGGSRAIEGVE
                     GLRMTWGRAVILEAMRRYLQQRRAMEPWEDPAGISHLEIQKLMYFANEADPDLALDFT
                     PGRYGPYSERVRHLLQGMEGAFTVGLGDGTARVLANQPISLTTKGTDAITDYLATDAA
                     ADRVSAAVDTVLRVIEGFEGPYGVELLASTHWVATREGAKEPATAAAAVRKWTKRKGR
                     IYSDDRIGVALDRILMTA"
     misc_feature    93568..93984
                     /locus_tag="BCG_0091"
                     /note="Macro domain, Poa1p_like family. The macro domain
                     is a high-affinity ADP-ribose binding module found in a
                     variety of proteins as a stand-alone domain or in
                     combination with other domains like in histone macroH2A
                     and some PARPs (poly ADP-ribose...; Region:
                     Macro_Poa1p_like; cd02901"
                     /db_xref="CDD:239230"
     misc_feature    order(93589..93594,93631..93633,93652..93654,93658..93663,
                     93916..93918,93922..93930)
                     /locus_tag="BCG_0091"
                     /note="ADP-ribose binding site [chemical binding]; other
                     site"
                     /db_xref="CDD:239230"
     misc_feature    93829..94500
                     /locus_tag="BCG_0091"
                     /note="Predicted phosphatase homologous to the C-terminal
                     domain of histone macroH2A1 [General function prediction
                     only]; Region: COG2110"
                     /db_xref="CDD:225021"
     gene            94650..95075
                     /locus_tag="BCG_0092"
                     /db_xref="GeneID:4697355"
     CDS             94650..95075
                     /locus_tag="BCG_0092"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_976194.1"
                     /db_xref="GI:121635971"
                     /db_xref="GeneID:4697355"
                     /translation="MCADAQPSGSVGLLGRNCPTATTRWRRAGEGLTAADTIEVKLWA
                     GKPRLHPLVPKRAVGVLLAVAHGQVAKTPSATRAIAFRHVRLMRVRWICAGNRGRKHK
                     RRCTTQYRSTQASKLQLHFKLRQTLNRLGGLQAMVSACG"
     gene            95211..96353
                     /gene="celA1"
                     /locus_tag="BCG_0093"
                     /db_xref="GeneID:4696098"
     CDS             95211..96353
                     /gene="celA1"
                     /locus_tag="BCG_0093"
                     /EC_number="3.2.1.4"
                     /note="Differs from Mb0063 by 1aa, A72D, and from Rv0062
                     by 2aa, A72D, V106I"
                     /codon_start=1
                     /transl_table=11
                     /product="cellulase celA1 (endoglucanase)"
                     /protein_id="YP_976195.1"
                     /db_xref="GI:121635972"
                     /db_xref="GeneID:4696098"
                     /translation="MTRRTGQRWRGTLPGRRPWTRPAPATCRRHLAFVELRHYFARVM
                     SSAIGSVARWIVPLLGVAAVASIGVIAAPVRVVRAPALILVDAANPLAGKPFYVDPAS
                     AAMVAARNANPPNAELTSVANTPQSYWLDQAFPPATVGGTVARYTGAAQAAGAMPVLT
                     LYGIPHRDCGSYASGGFATGTDYRGWIDAVASGLGSSPATIIVEPDALAMADCLSPDQ
                     RQERFDLVRYAVDTLTRDPAAAVYVDAGHSRWLSAEAMAARLNDVGVGRARGFSLNVS
                     NFYTTDEEIGYGEAISGLTNGSHYVIDTSRNGAGPAPDAPLNWCNPSGRALGAPPTTA
                     TAGAHADAYLWIKRPGESDGTCGRGEPQAGRFVSQYAIDLAHNAGQ"
     misc_feature    95502..96308
                     /gene="celA1"
                     /locus_tag="BCG_0093"
                     /note="Glycosyl hydrolases family 6; Region:
                     Glyco_hydro_6; pfam01341"
                     /db_xref="CDD:250545"
     gene            96582..98021
                     /locus_tag="BCG_0094"
                     /db_xref="GeneID:4697596"
     CDS             96582..98021
                     /locus_tag="BCG_0094"
                     /EC_number="1.-.-.-"
                     /codon_start=1
                     /transl_table=11
                     /product="oxidoreductase"
                     /protein_id="YP_976196.1"
                     /db_xref="GI:121635973"
                     /db_xref="GeneID:4697596"
                     /translation="MAREISRQTFLRGAAGALAAGAVFGSVRATADPAASGWEALSSA
                     LGGKVLQPDDGPQFATAKQVFNTNYNGYTPAVIVTPTSQLDVQKAMAFAAANNLKVAP
                     RGGGHSYVGASTANGAMVLDLRQLPGDINYDATTGRVTVTPATGLYAMHQVLAAAGRG
                     IPTGTCPTVGVAGHALGGGLGANSRHAGLLCDQLTSASVVLPSGQAVTASATDHPDLF
                     WALRGGGGGNFGVTTSLTFATFPSGDLDVVNLNFPPQSFAQVLVGWQNWLRTADRGSW
                     ALADATVDPLGTHCRILATCPAGSGGSVAAAIVSAVGTQPTGTENHTFNYLDLVRYLA
                     VGNLNPSPLGYVGGSDVFTTITPATAQGIASAVDAFPRGAGRMLAIMHALDGALATVS
                     PGATAFPWRRQSALVQWYVETSGSPSEATSWLNTAHQAVRAYSVGGYVNYLEVNQPPA
                     RYFGPNLSRLSAVRQKYDPSRVMFSGLNF"
     misc_feature    96699..98018
                     /locus_tag="BCG_0094"
                     /note="FAD/FMN-containing dehydrogenases [Energy
                     production and conversion]; Region: GlcD; COG0277"
                     /db_xref="CDD:223354"
     misc_feature    96801..97211
                     /locus_tag="BCG_0094"
                     /note="FAD binding domain; Region: FAD_binding_4;
                     pfam01565"
                     /db_xref="CDD:250709"
     misc_feature    97896..97997
                     /locus_tag="BCG_0094"
                     /note="Berberine and berberine like; Region: BBE;
                     pfam08031"
                     /db_xref="CDD:254594"
     gene            98279..101218
                     /locus_tag="BCG_0095"
                     /db_xref="GeneID:4696895"
     CDS             98279..101218
                     /locus_tag="BCG_0095"
                     /note="Differs from Mb0065 by 1aa, T435I, and from Rv0064
                     by 4aa, T435I, D457G, F550V, P906R"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_976197.1"
                     /db_xref="GI:121635974"
                     /db_xref="GeneID:4696895"
                     /translation="METGSPGKRPVLPKRARLLVTAGMGMLALLLFGPRLVDIYVDWL
                     WFGEVGFRSVWITVLLTRLAIVAAVALVVAGIVLAALLLAYRSRPFFVPDEPQRDPVA
                     PLRSAVMRRPRLFGWGIAVTLGVVCGLIASFDWVKVQLFVHGGTFGIVDPEFGYDIGF
                     FVFDLPFYRSVLNWLFVAVVLAFLASLLTHYLFGGLRLTTGRGMLTQAARVQLAVFAG
                     AVVLLKAVAYWLDRYELLSSGRKEPTFTGAGYTDIHAELPAKLVLVAIAVLCAVSFFT
                     AIFLRDLRIPAMAAALLVLSAILVGGLWPLLMEQFSVRPNAADVERPYIQRNIEATRE
                     AYRIGGDWVQYRSYPGIGTKQPRDVPVDVTTIAKVRLLDPHILSRTFTQQQQLKNFFS
                     FAEILDIDRYRIDGELQDYIVGVRELSPKSLTGNQTDWINKHTVYTHGNGFVAAPANR
                     VNAAARDAENISDSNSGYPIYAVSDIASLGSGRQVIPVEQPRVYYGEVIAQADPDYAI
                     VGGAPGSAPREYDTDTSKYTYTGAGGVSIGNWFNRTVFATKFAQHKFLFSREIGSESK
                     VLIHRDPKERVQRVAPWLTTDDNPYPVVVNGRIVWIVDAYTTLDTYPYAQRSSLEGPV
                     TSPTGIVRQGKQVSYVRNSVKATVDAYDGTVTLFQFDRDDPVLRTWMRAFPGTVKSED
                     QIPDELRAHFRYPEDLFEVQRSLLAKYHVDEPREFFTTNAFWSVPSDPTNDANATQPP
                     FYVLVGDQQSAQPSFRLASAMVGYNREFLSAYISAHSDPANYGKLTVLELPTDTLTQG
                     PQQIQNSMISDTRVASERTLLERSNRIHYGNLLSLPIADGGVLYVEPLYTERISTSPS
                     SSTFPQLSRVLVSVREPRTEGGVRVGYAPTLAESLDQVFGPGTGRVATAPGGDAASAP
                     PPGAGGPAPPQAVPPPRTTQPPAAPPRGPDVPPATVAELRETLADLRAVLDRLEKAID
                     AAETPGG"
     misc_feature    98279..101215
                     /locus_tag="BCG_0095"
                     /note="hypothetical protein; Provisional; Region:
                     PRK12438"
                     /db_xref="CDD:171499"
     gene            101285..101524
                     /locus_tag="BCG_0095A"
                     /db_xref="GeneID:4697388"
     CDS             101285..101524
                     /locus_tag="BCG_0095A"
                     /note="Differs from Rv0064A by 1aa,V48A"
                     /codon_start=1
                     /transl_table=11
                     /product="antitoxin"
                     /protein_id="YP_976198.1"
                     /db_xref="GI:121635975"
                     /db_xref="GeneID:4697388"
                     /translation="MATIQVRDLPEDVAETYRRRATAAGQSLQTYMRTKLIEGVRGRD
                     KAEVIEILEQALASTASPGISRETIEASRRELRGG"
     gene            101517..101918
                     /locus_tag="BCG_0096"
                     /db_xref="GeneID:4697383"
     CDS             101517..101918
                     /locus_tag="BCG_0096"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_976199.1"
                     /db_xref="GI:121635976"
                     /db_xref="GeneID:4697383"
                     /translation="MDECVVDAAAVVDALAGKGASAIVLRGLLKESISNAPHLLDAEV
                     GHALRRAVLSDEISEEQARAALDALPYLIDNRYPHSPRLIEYTWQLRHNVTFYDALYV
                     ALATALDVPLLTGDSRLAAAPGLPCEIKLVR"
     misc_feature    <101622..101888
                     /locus_tag="BCG_0096"
                     /note="PIN domain of the Pyrobaculum aerophilum Pae0151
                     and Pae2754 proteins and homologs; Region: PIN_Pae0151;
                     cd09873"
                     /db_xref="CDD:189043"
     misc_feature    order(101625..101633,101637..101654,101658..101666,
                     101700..101705,101709..101714,101721..101723,
                     101766..101768,101772..101777,101781..101786,
                     101796..101810,101814..101816,101859..101870,
                     101880..101882)
                     /locus_tag="BCG_0096"
                     /note="homotetrameric interface [polypeptide binding];
                     other site"
                     /db_xref="CDD:189043"
     misc_feature    order(101643..101645,101808..101810,101862..101864)
                     /locus_tag="BCG_0096"
                     /note="putative active site [active]"
                     /db_xref="CDD:189043"
     misc_feature    101862..101864
                     /locus_tag="BCG_0096"
                     /note="metal binding site [ion binding]; metal-binding
                     site"
                     /db_xref="CDD:189043"
     gene            complement(101970..104207)
                     /gene="icd2"
                     /locus_tag="BCG_0097c"
                     /db_xref="GeneID:4695423"
     CDS             complement(101970..104207)
                     /gene="icd2"
                     /locus_tag="BCG_0097c"
                     /EC_number="1.1.1.42"
                     /note="Differs from Rv0066c by 1aa, N117K"
                     /codon_start=1
                     /transl_table=11
                     /product="isocitrate dehydrogenase"
                     /protein_id="YP_976200.1"
                     /db_xref="GI:121635977"
                     /db_xref="GeneID:4695423"
                     /translation="MSAEQPTIIYTLTDEAPLLATYAFLPIVRAFAEPAGIKIEASDI
                     SVAARILAEFPDYLTEEQRVPDNLAELGRLTQLPDTNIIKLPNISASVPQLVAAIKEL
                     QDKGYAVPDYPADPNTDQEKAIKERYARCLGSAVNPVLRQGNSDRRAPKAVKEYARKH
                     PHSMGEWSMASRTHVAHMRHGDFYAGEKSMTLDRARNVRMELLAKSGKTIVLKPEVPL
                     DDGDVIDSMFMSKKALCDFYEEQMQDAFETGVMFSLHVKATMMKVSHPIVFGHAVRIF
                     YKDAFAKHQELFDDLGVNVNNGLSDLYSKIESLPASQRDEIIEDLHRCHEHRPELAMV
                     DSARGISNFHSPSDVIVDASMPAMIRAGGKMYGADGKLKDTKAVNPESTFSRIYQEII
                     NFCKTNGQFDPTTMGTVPNVGLMAQQAEEYGSHDKTFEIPEDGVANIVDVATGEVLLT
                     ENVEAGDIWRMCIVKDAPIRDWVKLAVTRARISGMPVLFWLDPYRPHENELIKKVKTY
                     LKDHDTEGLDIQIMSQVRSMRYTCERLVRGLDTIAATGNILRDYLTDLFPILELGTSA
                     KMLSVVPLMAGGGMYETGAGGSAPKHVKQLVEENHLRWDSLGEFLALGAGFEDIGIKT
                     GNERAKLLGKTLDAAIGKLLDNDKSPSRKTGELDNRGSQFYLAMYWAQELAAQTDDQQ
                     LAEHFASLADVLTKNEDVIVRELTEVQGEPVDIGGYYAPDSDMTTAVMRPSKTFNAAL
                     EAVQG"
     misc_feature    complement(101973..104207)
                     /gene="icd2"
                     /locus_tag="BCG_0097c"
                     /note="Monomeric isocitrate dehydrogenase [Energy
                     production and conversion]; Region: Icd; COG2838"
                     /db_xref="CDD:225394"
     gene            complement(104325..104894)
                     /locus_tag="BCG_0098c"
                     /db_xref="GeneID:4699214"
     CDS             complement(104325..104894)
                     /locus_tag="BCG_0098c"
                     /codon_start=1
                     /transl_table=11
                     /product="TetR family transcriptional regulator"
                     /protein_id="YP_976201.1"
                     /db_xref="GI:121635978"
                     /db_xref="GeneID:4699214"
                     /translation="MAPTDRRVRADAARNRARVLEVAYQTFAADGLSVPVDEIARRAG
                     VGAGTVYRHFPTKEALFQAVIADRMHRIIDKGHALLKSKHPGDALFAFLRSMVLQWGA
                     TDRGLVEALAGVGIEISSAAPEAEADFLDLLTDLLRAAQRAGTVRPDVDVLEVKTLLV
                     GCQAMQSYNAELAAKVTDVALDGLRANRK"
     misc_feature    complement(104337..104837)
                     /locus_tag="BCG_0098c"
                     /note="Transcriptional regulator [Transcription]; Region:
                     AcrR; COG1309"
                     /db_xref="CDD:224228"
     misc_feature    complement(104703..104837)
                     /locus_tag="BCG_0098c"
                     /note="Bacterial regulatory proteins, tetR family; Region:
                     TetR_N; pfam00440"
                     /db_xref="CDD:249860"
     gene            104997..105908
                     /locus_tag="BCG_0099"
                     /db_xref="GeneID:4697775"
     CDS             104997..105908
                     /locus_tag="BCG_0099"
                     /EC_number="1.-.-.-"
                     /note="Differs from Rv0068 by 1aa, L214V"
                     /codon_start=1
                     /transl_table=11
                     /product="short chain dehydrogenase"
                     /protein_id="YP_976202.1"
                     /db_xref="GI:121635979"
                     /db_xref="GeneID:4697775"
                     /translation="MTKWTAADIPDQTGRTAVITGANTGLGFETAAALAAHGAHVVLA
                     VRNLDKGKQAAARITEATPGAEVELQELDLTSLASVRAAAAQLKSDHQRIDLLINNAG
                     VMYTPRQTTADGFEMQFGTNHLGHFALTGLLIDRLLPVAGSRVVTISSVGHRIRAAIH
                     FDDLQWERRYRRVAAYGQAKLANLLFTYELQRRLAPGGTTIAVASHPGVSNTELVRNM
                     PRPLVAVAAILAPLMQDAELGALPTLRAATDPAVRGGQYFGPDGFGEIRGYPKVVASS
                     AQSHDEQLQRRLWAVSEELTGVVYPVG"
     misc_feature    104997..105902
                     /locus_tag="BCG_0099"
                     /note="short chain dehydrogenase; Provisional; Region:
                     PRK06197"
                     /db_xref="CDD:235737"
     misc_feature    105036..105863
                     /locus_tag="BCG_0099"
                     /note="retinol dehydrogenase (retinol-DH), Light dependent
                     Protochlorophyllide (Pchlide) OxidoReductase (LPOR) and
                     related proteins, classical (c) SDRs; Region:
                     retinol-DH_like_SDR_c_like; cd05327"
                     /db_xref="CDD:212492"
     misc_feature    order(105057..105059,105063..105074,105129..105137,
                     105210..105218,105294..105302,105357..105359,
                     105456..105458,105459..105461,105522..105524,
                     105534..105536,105615..105626,105630..105635)
                     /locus_tag="BCG_0099"
                     /note="putative NAD(P) binding site [chemical binding];
                     other site"
                     /db_xref="CDD:212492"
     misc_feature    order(105360..105362,105459..105461,105522..105524,
                     105534..105536)
                     /locus_tag="BCG_0099"
                     /note="active site"
                     /db_xref="CDD:212492"
     gene            complement(105933..107318)
                     /gene="sdaA"
                     /locus_tag="BCG_0100c"
                     /db_xref="GeneID:4696487"
     CDS             complement(105933..107318)
                     /gene="sdaA"
                     /locus_tag="BCG_0100c"
                     /EC_number="4.3.1.17"
                     /codon_start=1
                     /transl_table=11
                     /product="l-serine dehydratase sdaA"
                     /protein_id="YP_976203.1"
                     /db_xref="GI:121635980"
                     /db_xref="GeneID:4696487"
                     /translation="MTISVFDLFTIGIGPSSSHTVGPMRAANQFVVALRRRGHLDDLE
                     AMRVDLFGSLAATGAGHGTMSAILLGLEGCQPETITTEHKERRLAEIAASGVTRIGGV
                     IPVPLTERDIDLHPDIVLPTHPNGMTFTAAGPHGRVLATETYFSVGGGFIVTEQTSGN
                     SGQHPCSVALPYVSAQELLDICDRLDVSISEAALRNETCCRTENEVRAALLHLRDVMV
                     ECEQRSIAREGLLPGGLRVRRRAKVWYDRLNAEDPTRKPEFAEDWVNLVALAVNEENA
                     SGGRVVTAPTNGAAGIVPAVLHYAIHYTSAGAGDPDDVTVRFLLTAGAIGSLFKERAS
                     ISGAEVGCQGEVGSAAAMAAAGLAEILGGTPRQVENAAEIAMEHSLGLTCDPIAGLVQ
                     IPCIERNAISAGKAINAARMALRGDGIHRVTLDQVIDTMRATGADMHTKYKETSAGGL
                     AINVAVNIVEC"
     misc_feature    complement(105957..107312)
                     /gene="sdaA"
                     /locus_tag="BCG_0100c"
                     /note="L-serine dehydratase, iron-sulfur-dependent, single
                     chain form; Region: sda_mono; TIGR00720"
                     /db_xref="CDD:188076"
     misc_feature    complement(106839..107288)
                     /gene="sdaA"
                     /locus_tag="BCG_0100c"
                     /note="Serine dehydratase beta chain; Region: SDH_beta;
                     pfam03315"
                     /db_xref="CDD:251868"
     misc_feature    complement(105960..106772)
                     /gene="sdaA"
                     /locus_tag="BCG_0100c"
                     /note="Serine dehydratase alpha chain; Region: SDH_alpha;
                     pfam03313"
                     /db_xref="CDD:251866"
     gene            complement(107315..108592)
                     /gene="glyA"
                     /locus_tag="BCG_0101c"
                     /db_xref="GeneID:4697898"
     CDS             complement(107315..108592)
                     /gene="glyA"
                     /locus_tag="BCG_0101c"
                     /EC_number="2.1.2.1"
                     /note="catalyzes the reaction of glycine with
                     5,10-methylenetetrahydrofolate to form L-serine and
                     tetrahydrofolate"
                     /codon_start=1
                     /transl_table=11
                     /product="serine hydroxymethyltransferase"
                     /protein_id="YP_976204.1"
                     /db_xref="GI:121635981"
                     /db_xref="GeneID:4697898"
                     /translation="MNTLNDSLTAFDPDIAALIDGELRRQESGLEMIASENYAPLAVM
                     QAQGSVLTNKYAEGYPGRRYYGGCEFVDGVEQLAIDRVKALFGAEYANVQPHSGATAN
                     AATMHALLNPGDTILGLSLAHGGHLTHGMRINFSGKLYHATAYEVSKEDYLVDMDAVA
                     EAARTHRPKMIIAGWSAYPRQLDFARFRAIADEVDAVLMVDMAHFAGLVAAGVHPSPV
                     PHAHVVTSTTHKTLGGPRGGIILCNDPAIAKKINSAVFPGQQGGPLGHVIAAKATAFK
                     MAAQPEFAQRQQRCLDGARILAGRLTQPDVAERGIAVLTGGTDVHLVLVDLRDAELDG
                     QQAEDRLAAVDITVNRNAVPFDPRPPMITSGLRIGTPALAARGFSHNDFRAVADLIAA
                     ALTATNDDQLGPLRAQVQRLAARYPLYPELHRT"
     misc_feature    complement(107357..108559)
                     /gene="glyA"
                     /locus_tag="BCG_0101c"
                     /note="Serine-glycine hydroxymethyltransferase (SHMT).
                     This family belongs to pyridoxal phosphate (PLP)-dependent
                     aspartate aminotransferase superfamily (fold I). SHMT
                     carries out interconversion of serine and glycine; it
                     catalyzes the transfer of hydroxymethyl...; Region: SHMT;
                     cd00378"
                     /db_xref="CDD:99733"
     misc_feature    complement(order(107747..107749,107801..107803,
                     108176..108181,108284..108286,108305..108307,
                     108350..108352,108374..108379,108431..108433,
                     108485..108487,108500..108502,108527..108532,
                     108551..108553,108557..108559))
                     /gene="glyA"
                     /locus_tag="BCG_0101c"
                     /note="dimer interface [polypeptide binding]; other site"
                     /db_xref="CDD:99733"
     misc_feature    complement(order(107492..107494,107885..107887,
                     107903..107908,107981..107983,107990..107992,
                     108065..108067,108215..108217,108296..108301,
                     108398..108400,108428..108430,108488..108490))
                     /gene="glyA"
                     /locus_tag="BCG_0101c"
                     /note="glycine-pyridoxal phosphate binding site [chemical
                     binding]; other site"
                     /db_xref="CDD:99733"
     misc_feature    complement(order(107492..107494,107903..107905,
                     108215..108217,108488..108490))
                     /gene="glyA"
                     /locus_tag="BCG_0101c"
                     /note="active site"
                     /db_xref="CDD:99733"
     misc_feature    complement(order(107540..107542,107825..107827,
                     108212..108214,108218..108220,108230..108232,
                     108401..108403,108422..108424))
                     /gene="glyA"
                     /locus_tag="BCG_0101c"
                     /note="folate binding site [chemical binding]; other site"
                     /db_xref="CDD:99733"
     gene            109182..109934
                     /locus_tag="BCG_0102"
                     /db_xref="GeneID:4697847"
     CDS             109182..109934
                     /locus_tag="BCG_0102"
                     /note="In Mycobacterium bovis BCG Pasteur, a 45 bp
                     insertion (5 copies of VDP repeat) leads to longer
                     products compared to its homologs in Mycobacterium
                     tuberculosis strain H37Rv (250 aa versus 235 aa) and
                     Mycobacterium bovis (250 aa versus 238 aa)"
                     /codon_start=1
                     /transl_table=11
                     /product="maturase"
                     /protein_id="YP_976205.1"
                     /db_xref="GI:121635982"
                     /db_xref="GeneID:4697847"
                     /translation="MSSITVSVDPVDPVDPVDPVDPVDPVDPVDPVDPVDPVDAVVAA
                     GSDGLTVARIESEIGALEFLNELRTELKSGQFRPQPVRERKIPKPGGLGKVRRLGIPT
                     VADRVVQAALKLVLEPIFETDFEPVSYGFRPARRAHDTIAEIHLFGTQEYRWVLDADI
                     KACFDRIDHADLMDRVRHRIKDKRVLRLVNWQRIRHRWNWTDVRRWLTDPTGRWHPIS
                     ADGITLFNPAAVPIRRYRYRGNTIPTPWTQAV"
     misc_feature    <109314..109901
                     /locus_tag="BCG_0102"
                     /note="Retron-type reverse transcriptase [DNA replication,
                     recombination, and repair]; Region: COG3344"
                     /db_xref="CDD:225881"
     misc_feature    109425..>109748
                     /locus_tag="BCG_0102"
                     /note="RT_G2_intron: Reverse transcriptases (RTs) with
                     group II intron origin. RT transcribes DNA using RNA as
                     template. Proteins in this subfamily are found in
                     bacterial and mitochondrial group II introns. Their most
                     probable ancestor was a retrotransposable...; Region:
                     RT_G2_intron; cd01651"
                     /db_xref="CDD:238828"
     misc_feature    109656..109673
                     /locus_tag="BCG_0102"
                     /note="putative NTP binding site [chemical binding]; other
                     site"
                     /db_xref="CDD:238828"
     repeat_region   109977..110291
                     /note="REP'-1, len: 315 nt. Equivalent to REP', len: 315
                     nt, from Mycobacterium tuberculosis strain H37Rv, (100.0%
                     identity in 315 nt overlap). Probable pseudogene fragment,
                     len: 105 aa; similar to many Mycobacterium tuberculosis
                     proteins inside REP13E12 elements eg. TR:Q50655
                     (EMBL:Z95390) MTCY13E12.20 (317 aa), FASTA scores; opt:
                     324 z-score: 432.5 E(): 6.8e-17, 43.4% identity in 99 aa
                     overlap, but no possible startsite"
                     /rpt_family="REP"
     gene            110365..111414
                     /locus_tag="BCG_0103"
                     /db_xref="GeneID:4697457"
     CDS             110365..111414
                     /locus_tag="BCG_0103"
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine ABC transporter"
                     /protein_id="YP_976206.1"
                     /db_xref="GI:121635983"
                     /db_xref="GeneID:4697457"
                     /translation="MLFAALRDMQWRKRRLVITIISTGLIFGMTLVLTGLANGFRVEA
                     RHTVDSMGVDVFVVRSGAAGPFLGSIPFPDVDLARVAAEPGVMAAAPLGSVGTIMKEG
                     TSTRNVTVFGAPEHGPGMPRVSEGRSPSKPDEVAASSTMGRHLGDTVEVGARRLRVVG
                     IVPNSTALAKIPNVFLTTEGLQKLAYNGQPNITSIGIIGMPRQLPEGYQTFDRVGAVN
                     DLVRPLKVAVNSISIVAVLLWIVAVLIVGSVVYLSALERLRDFAVFKAIGTPTRSIMA
                     GLALQALVIALLAAVVGVVLAQVLAPLFPMIVAVPVGAYLALPVAAIVIGLFASVAGL
                     KRVVTVDPAQAFGGP"
     misc_feature    110365..111402
                     /locus_tag="BCG_0103"
                     /note="ABC-type transport system, involved in lipoprotein
                     release, permease component [Cell envelope biogenesis,
                     outer membrane]; Region: LolE; COG4591"
                     /db_xref="CDD:226957"
     misc_feature    110377..110955
                     /locus_tag="BCG_0103"
                     /note="MacB-like periplasmic core domain; Region:
                     MacB_PCD; pfam12704"
                     /db_xref="CDD:257236"
     misc_feature    111058..111390
                     /locus_tag="BCG_0103"
                     /note="FtsX-like permease family; Region: FtsX; pfam02687"
                     /db_xref="CDD:251477"
     gene            111417..112409
                     /locus_tag="BCG_0104"
                     /db_xref="GeneID:4695394"
     CDS             111417..112409
                     /locus_tag="BCG_0104"
                     /note="In Mycobacterium tuberculosis strain H37Rv, Rv0073
                     exists as a single gene as in Mycobacterium bovis BCG
                     Pasteur. In Mycobacterium bovis, a frameshift due to a
                     single base deletion (a-*) splits Rv0073 into 2 parts,
                     Mb0074 and Mb0075"
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine ABC transporter ATP-binding protein"
                     /protein_id="YP_976207.1"
                     /db_xref="GI:121635984"
                     /db_xref="GeneID:4695394"
                     /translation="MGDLSIQNLVVEYYSGGYALRPINGLNLDVAAGSLVMLLGPSGC
                     GKTTLLSCLGGILRPKSGAIKFDEVDITTLQGAELANYRRNKVGIVFQAFNLVPSLTA
                     VENVMVPLRSAGMSRRASRRRAEELLARVNLAERMNHRPGDLSGGQQQRVAVARAIAL
                     DPPLILADEPTAHLDFIQVEEVLRLIRELADGERVVVVATHDSRMLPMADRVVELTPD
                     FAETNRPPETVHLQAGEVLFEQSTMGDLIYVVSEGEFEIVHELADGGEELVKVAGPGD
                     YFGEIGVLFHLPRSATVRARSDATAVGYTVQAFRERLGVGGLRDLIEHRALAND"
     misc_feature    111426..112061
                     /locus_tag="BCG_0104"
                     /note="ATP-binding cassette domain of the transporters
                     involved in export of lipoprotein and macrolide, and cell
                     division protein; Region: ABC_MJ0796_LolCDE_FtsE; cd03255"
                     /db_xref="CDD:213222"
     misc_feature    111426..112061
                     /locus_tag="BCG_0104"
                     /note="ABC-type antimicrobial peptide transport system,
                     ATPase component [Defense mechanisms]; Region: SalX;
                     COG1136"
                     /db_xref="CDD:224059"
     misc_feature    111534..111557
                     /locus_tag="BCG_0104"
                     /note="Walker A/P-loop; other site"
                     /db_xref="CDD:213222"
     misc_feature    order(111543..111548,111552..111560,111690..111692,
                     111918..111923,112017..112019)
                     /locus_tag="BCG_0104"
                     /note="ATP binding site [chemical binding]; other site"
                     /db_xref="CDD:213222"
     misc_feature    111681..111692
                     /locus_tag="BCG_0104"
                     /note="Q-loop/lid; other site"
                     /db_xref="CDD:213222"
     misc_feature    111846..111875
                     /locus_tag="BCG_0104"
                     /note="ABC transporter signature motif; other site"
                     /db_xref="CDD:213222"
     misc_feature    111906..111923
                     /locus_tag="BCG_0104"
                     /note="Walker B; other site"
                     /db_xref="CDD:213222"
     misc_feature    111930..111941
                     /locus_tag="BCG_0104"
                     /note="D-loop; other site"
                     /db_xref="CDD:213222"
     misc_feature    112005..112025
                     /locus_tag="BCG_0104"
                     /note="H-loop/switch region; other site"
                     /db_xref="CDD:213222"
     misc_feature    112065..>112355
                     /locus_tag="BCG_0104"
                     /note="cAMP-binding proteins - catabolite gene activator
                     and regulatory subunit of cAMP-dependent protein kinases
                     [Signal transduction mechanisms]; Region: Crp; COG0664"
                     /db_xref="CDD:223736"
     misc_feature    112095..112358
                     /locus_tag="BCG_0104"
                     /note="effector domain of the CAP family of transcription
                     factors; members include CAP (or cAMP receptor protein
                     (CRP)), which binds cAMP, FNR (fumarate and nitrate
                     reduction), which uses an iron-sulfur cluster to sense
                     oxygen) and CooA, a heme containing CO...; Region: CAP_ED;
                     cd00038"
                     /db_xref="CDD:237999"
     misc_feature    order(112251..112256,112281..112289)
                     /locus_tag="BCG_0104"
                     /note="ligand binding site [chemical binding]; other site"
                     /db_xref="CDD:237999"
     misc_feature    112347..112355
                     /locus_tag="BCG_0104"
                     /note="flexible hinge region; other site"
                     /db_xref="CDD:237999"
     gene            112489..113724
                     /locus_tag="BCG_0105"
                     /db_xref="GeneID:4698175"
     CDS             112489..113724
                     /locus_tag="BCG_0105"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_976208.1"
                     /db_xref="GI:121635985"
                     /db_xref="GeneID:4698175"
                     /translation="MGDLSISQVSARPGRIGIRARQMFDGYRFQRGPVLVVVEDGRIS
                     AVDFAGSACPDMNLVDLGESTLLPGLVDAHAHLCWDPDGRPEDLAGDPHAVLVGRARR
                     HAAAALRSGITTIRDLGDRDYAALALREEYRQKTTVGPELVVSGPPLTRSGGHCWFLG
                     GVADSVEELVDAVQERAARGADWIKVMATGGFVTTASDPWQPQYGSGQLAAVVAAAEQ
                     VGLPVTAHAHATAGIAAAVAAGVDGIEHCTFLSEGSAAASPDVVEAIVAQGVWCGMTI
                     PRVYPEMPENLVAVVQDGWRNIRRLIDAGARVALSTDAGVAPGRRHDVLPDDLVYLSR
                     HGFTSTEVLTGATAAAAASCGLGHRKGRIAPGYDADLLAVAAGVDHDPAGLCDVKAVW
                     RSGTQVPLQASAVGYNTPS"
     misc_feature    112501..113700
                     /locus_tag="BCG_0105"
                     /note="Imidazolonepropionase and related amidohydrolases
                     [Secondary metabolites biosynthesis, transport, and
                     catabolism]; Region: HutI; COG1228"
                     /db_xref="CDD:224149"
     misc_feature    112582..>112722
                     /locus_tag="BCG_0105"
                     /note="Superfamily of metallo-dependent hydrolases (also
                     called amidohydrolase superfamily) is a large group of
                     proteins that show conservation in their 3-dimensional
                     fold (TIM barrel) and in details of their active site. The
                     vast majority of the members have a...; Region:
                     metallo-dependent_hydrolases; cl00281"
                     /db_xref="CDD:271457"
     misc_feature    112663..113643
                     /locus_tag="BCG_0105"
                     /note="Metallo-dependent hydrolases, subgroup A is part of
                     the superfamily of metallo-dependent hydrolases, a large
                     group of proteins that show conservation in their
                     3-dimensional fold (TIM barrel) and in details of their
                     active site. The vast majority of the...; Region:
                     Met_dep_hydrolase_A; cd01299"
                     /db_xref="CDD:238624"
     misc_feature    order(112708..112710,112714..112716,113164..113166,
                     113224..113226,113425..113427)
                     /locus_tag="BCG_0105"
                     /note="active site"
                     /db_xref="CDD:238624"
     gene            113737..114909
                     /locus_tag="BCG_0106"
                     /db_xref="GeneID:4696342"
     CDS             113737..114909
                     /locus_tag="BCG_0106"
                     /EC_number="2.6.1.-"
                     /note="Differs from Rv0075 and Mb0077 by 1aa, G326D"
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase"
                     /protein_id="YP_976209.1"
                     /db_xref="GI:121635986"
                     /db_xref="GeneID:4696342"
                     /translation="MQDSIFNLLTEEQLRGRNTLKWNYFGPDVVPLWLAEMDFPTAPA
                     VLDGVRACVDNEEFGYPPLGEDSLPRATADWCRQRYGWCPRPDWVRVVPDVLKGMEVV
                     VEFLTRPESPVALPVPAYMPFFDVLHVTGRQRVEVPMVQQDSGRYLLDLDALQAAFVR
                     GAGSVIICNPNNPLGTAFTEAELRAIVDIAARHGARVIADEIWAPVVYGSRHVAAASV
                     SEAAAEVVVTLVSASKGWNLPGLMCAQVILSNRRDAHDWDRINMLHRMGASTVGIRAN
                     IAAYHHGESWLDELLPYLRANRDHLARALPELAPGVEVNAPDGTYLSWVGFRALALPS
                     EPAEYLLSKAKVALSPGIPFGAAVGSGFARLNFATTRAILDRAIEAIAAALRDIID"
     misc_feature    113779..114894
                     /locus_tag="BCG_0106"
                     /note="putative C-S lyase; Region: C_S_lyase_PatB;
                     TIGR04350"
                     /db_xref="CDD:213963"
     misc_feature    113824..114885
                     /locus_tag="BCG_0106"
                     /note="Aspartate aminotransferase family. This family
                     belongs to pyridoxal phosphate (PLP)-dependent aspartate
                     aminotransferase superfamily (fold I). Pyridoxal phosphate
                     combines with an alpha-amino acid to form a compound
                     called a Schiff base or aldimine...; Region: AAT_like;
                     cd00609"
                     /db_xref="CDD:99734"
     misc_feature    order(114016..114024,114094..114096,114250..114252,
                     114343..114345,114427..114429,114433..114438,
                     114460..114462)
                     /locus_tag="BCG_0106"
                     /note="pyridoxal 5'-phosphate binding site [chemical
                     binding]; other site"
                     /db_xref="CDD:99734"
     misc_feature    order(114025..114027,114124..114126,114322..114324,
                     114454..114462,114550..114552,114559..114561)
                     /locus_tag="BCG_0106"
                     /note="homodimer interface [polypeptide binding]; other
                     site"
                     /db_xref="CDD:99734"
     misc_feature    114436..114438
                     /locus_tag="BCG_0106"
                     /note="catalytic residue [active]"
                     /db_xref="CDD:99734"
     gene            complement(114924..115313)
                     /locus_tag="BCG_0107c"
                     /db_xref="GeneID:4696055"
     CDS             complement(114924..115313)
                     /locus_tag="BCG_0107c"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_976210.1"
                     /db_xref="GI:121635987"
                     /db_xref="GeneID:4696055"
                     /translation="MPAVTTPSNHWGDERRKLSHQPPVRGQILGRRQARRLSQHFARV
                     GVEAPPKRLQEMLLGAPAADEEWTDVKFALIVTQLNHEKRVAKFHRLQRRATHSLICL
                     GLVLVALNFLICLAYIFFSLTQHAAAL"
     gene            complement(115377..116207)
                     /locus_tag="BCG_0108c"
                     /db_xref="GeneID:4695393"
     CDS             complement(115377..116207)
                     /locus_tag="BCG_0108c"
                     /EC_number="1.-.-.-"
                     /codon_start=1
                     /transl_table=11
                     /product="oxidoreductase"
                     /protein_id="YP_976211.1"
                     /db_xref="GI:121635988"
                     /db_xref="GeneID:4695393"
                     /translation="MSTIDISAGTIHYEATGPETGRPVVFVHGYMMGGQLWRRVSERL
                     AGRGLRCIAPTWPLGAHPKPLRPGADQTIGGVAGIVADVLAALELKDVVLVGNDTGGV
                     VTQLVAVHYPERLGALVLTSCDAFEHFPPPILKPVILAAKSATLFRAAIQVMRAPAAR
                     NRAYAGLSHHNIDHLTRAWVRPALSNPAIAEDLRQLSLSLRTEVTTAVAARLPEFDKP
                     ALIAWSADDVFFALENGQRLAATIPRARFEVIEGARTFSMVDSPDRLADQLSTVAVRT
                     "
     misc_feature    complement(<115872..116165)
                     /locus_tag="BCG_0108c"
                     /note="Esterases and lipases (includes fungal lipases,
                     cholinesterases, etc.)  These enzymes act on carboxylic
                     esters (EC: 3.1.1.-). The catalytic apparatus involves
                     three residues (catalytic triad): a serine, a glutamate or
                     aspartate and a histidine.These...; Region:
                     Esterase_lipase; cl21494"
                     /db_xref="CDD:271914"
     misc_feature    complement(115407..116138)
                     /locus_tag="BCG_0108c"
                     /note="Alpha/beta hydrolase family; Region: Abhydrolase_6;
                     pfam12697"
                     /db_xref="CDD:257231"
     gene            116269..116874
                     /locus_tag="BCG_0109"
                     /db_xref="GeneID:4698145"
     CDS             116269..116874
                     /locus_tag="BCG_0109"
                     /note="Differs from Rv0078 by 1aa, V113I"
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulatory protein"
                     /protein_id="YP_976212.1"
                     /db_xref="GI:121635989"
                     /db_xref="GeneID:4698145"
                     /translation="MEIKRRTQEERSAATREALITGARKLWGLRGYAEVGTPEIATEA
                     GVTRGAMYHQFADKAALFRDVVEVVEQDVMARMATLVAASGAATPADAIRAAVDAWLE
                     VSGDPEVRQLVLLDAPVVLGWAGFRDVAQRYSLGMTEQLITEAIRAGQLARQPVRPLA
                     QVLIGALDEAAMFIATADDPKRARRETRQVLRRLIDGMLNG"
     misc_feature    116281..116826
                     /locus_tag="BCG_0109"
                     /note="Transcriptional regulator [Transcription]; Region:
                     AcrR; COG1309"
                     /db_xref="CDD:224228"
     misc_feature    116323..116457
                     /locus_tag="BCG_0109"
                     /note="Bacterial regulatory proteins, tetR family; Region:
                     TetR_N; pfam00440"
                     /db_xref="CDD:249860"
     gene            complement(116949..117542)
                     /locus_tag="BCG_0110c"
                     /db_xref="GeneID:4696050"
     CDS             complement(116949..117542)
                     /locus_tag="BCG_0110c"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_976213.1"
                     /db_xref="GI:121635990"
                     /db_xref="GeneID:4696050"
                     /translation="MNAVESTLRRVAKDLTGLRQRWALVGGFAVSARSEPRFTRDVDI
                     VVAVANDDAAESLVRQLLTQQYHLLASVEQDAARRLAAVRLGATADTAANVVVDLLFA
                     SCGIEPEIAEAAEEIEILPDLVAPVATTAHLIAMKLLARDDDRRPQDRSDLRALVDAA
                     SPQDIQDARKAIELITLRGFHRDRDLAAEWTRLAAKW"
     misc_feature    complement(<117069..117494)
                     /locus_tag="BCG_0110c"
                     /note="Nucleotidyl transferase of unknown function
                     (DUF1814); Region: DUF1814; pfam08843"
                     /db_xref="CDD:255068"
     gene            complement(117539..117751)
                     /locus_tag="BCG_0111c"
                     /db_xref="GeneID:4697451"
     CDS             complement(117539..117751)
                     /locus_tag="BCG_0111c"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_976214.1"
                     /db_xref="GI:121635991"
                     /db_xref="GeneID:4697451"
                     /translation="MSVAVSVAAQKLRLALDMYEVGEQMQRMRLGRERPNADVVEIEA
                     AIDAWRMTRPGAEEGDSAGPTSTRFT"
     gene            117945..118766
                     /locus_tag="BCG_0112"
                     /db_xref="GeneID:4697996"
     CDS             117945..118766
                     /locus_tag="BCG_0112"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_976215.1"
                     /db_xref="GI:121635992"
                     /db_xref="GeneID:4697996"
                     /translation="MEPKRSRLVVCAPEPSHAREFPDVAVFSGGRANASQAERLARAV
                     GRVLADRGVTGGARVRLTMANCADGPTLVQINLQVGDTPLRAQAATAGIDDLRPALIR
                     LDRQIVRASAQWCPRPWPDRPRRRLTTPAEALVTRRKPVVLRRATPLQAIAAMDAMDY
                     DVHLFTDAETGEDAVVYRAGPSGLRLARQHHVFPPGWSRCRAPAGPPVPLIVNSRPTP
                     VLTEAAAVDRAREHGLPFLFFTDQATGRGQLLYSRYDGNLGLITPTGDGVADGLA"
     gene            118763..119221
                     /locus_tag="BCG_0113"
                     /db_xref="GeneID:4695860"
     CDS             118763..119221
                     /locus_tag="BCG_0113"
                     /note="Differs from Mb0083 by 1aa, C35R, and from Rv0080
                     by 2aa, C35R, V60G"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_976216.1"
                     /db_xref="GI:121635993"
                     /db_xref="GeneID:4695860"
                     /translation="MSPGSRRASPQSAREVVELDRDEAMRLLASVDHGCVVFTRAALP
                     AIRPVNHLVVDGRVIVRTRLTAKVSVAVRSSADAGVVVAYEADDLDPRRRTGWSVVVT
                     GLATEVSDPEQVARYQRLLHPWVNMAMDTVVAIEPEIVTGIRIVADSRTP"
     misc_feature    118820..119110
                     /locus_tag="BCG_0113"
                     /note="Pyridoxamine 5'-phosphate oxidase; Region:
                     Pyridox_ox_2; pfam12900"
                     /db_xref="CDD:257388"
     gene            119316..119660
                     /locus_tag="BCG_0114"
                     /db_xref="GeneID:4698066"
     CDS             119316..119660
                     /locus_tag="BCG_0114"
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulatory protein"
                     /protein_id="YP_976217.1"
                     /db_xref="GI:121635994"
                     /db_xref="GeneID:4698066"
                     /translation="MESEPLYKLKAEFFKTLAHPARIRILELLVERDRSVGELLSSDV
                     GLESSNLSQQLGVLRRAGVVAARRDGNAMIYSIAAPDIAELLAVARKVLARVLSDRVA
                     VLEDLRAGGSAT"
     misc_feature    119355..119558
                     /locus_tag="BCG_0114"
                     /note="Arsenical Resistance Operon Repressor and similar
                     prokaryotic, metal regulated homodimeric repressors. ARSR
                     subfamily of helix-turn-helix bacterial transcription
                     regulatory proteins (winged helix topology). Includes
                     several proteins that appear to...; Region: HTH_ARSR;
                     cd00090"
                     /db_xref="CDD:238042"
     misc_feature    order(119355..119360,119364..119366,119373..119375,
                     119382..119387,119394..119399,119406..119408,
                     119499..119501)
                     /locus_tag="BCG_0114"
                     /note="dimerization interface [polypeptide binding]; other
                     site"
                     /db_xref="CDD:238042"
     misc_feature    order(119358..119363,119373..119381,119418..119426,
                     119454..119465,119469..119474,119481..119486,
                     119490..119495,119511..119519,119532..119540)
                     /locus_tag="BCG_0114"
                     /note="putative DNA binding site [nucleotide binding];
                     other site"
                     /db_xref="CDD:238042"
     misc_feature    order(119418..119420,119427..119429)
                     /locus_tag="BCG_0114"
                     /note="putative Zn2+ binding site [ion binding]; other
                     site"
                     /db_xref="CDD:238042"
     gene            119665..120144
                     /locus_tag="BCG_0115"
                     /db_xref="GeneID:4695863"
     CDS             119665..120144
                     /locus_tag="BCG_0115"
                     /EC_number="1.-.-.-"
                     /note="Differs from Rv0082 by 1aa, R74Q"
                     /codon_start=1
                     /transl_table=11
                     /product="oxidoreductase"
                     /protein_id="YP_976218.1"
                     /db_xref="GI:121635995"
                     /db_xref="GeneID:4695863"
                     /translation="MGWVAKIFRVGRVVEPAAPLPAAIAEPPAGVRGSLQIRHVDAGS
                     CNGCEVEISGAFGPVYDAERFGARLVASPRHADALLVTGVVTHNMAGPLRKTLEATPR
                     PRVVIACGDCALNRGVFADAYGVVGAVGEVVPVDVEIAGCPPTPAAIMAALRSVTGK"
     misc_feature    119752..120141
                     /locus_tag="BCG_0115"
                     /note="Ni,Fe-hydrogenase III small subunit [Energy
                     production and conversion]; Region: COG3260"
                     /db_xref="CDD:225799"
     gene            120141..122069
                     /locus_tag="BCG_0116"
                     /db_xref="GeneID:4697023"
     CDS             120141..122069
                     /locus_tag="BCG_0116"
                     /EC_number="1.-.-.-"
                     /note="In Mycobacterium bovis, a single base transversion
                     (a-t) leads to a slightly longer product compared to its
                     homolog in Mycobacterium tuberculosis strain H37Rv (642 aa
                     versus 640 aa). Differs from Mb0086 by 1aa, A177V"
                     /codon_start=1
                     /transl_table=11
                     /product="oxidoreductase"
                     /protein_id="YP_976219.1"
                     /db_xref="GI:121635996"
                     /db_xref="GeneID:4697023"
                     /translation="MTAAPTAGGVVTSGVGVAGVGVGLLGMFGPVRVVHVGWLLPLSG
                     VHIELDRLGGFFMALTGAVAAPVGCYLIGYVRREHLGRVPMAVVPLFVAAMLLVPAAG
                     SVTTFLLAWELMAIASLILVLSEHARPQVRSAGLWYAVMTQLGFIAILVGLVVLAAAG
                     GSDRFAGLGAVCDGVRAAVFMLTLVGFGSKAGLVPLHAWLPRAHPEAPSPVSALMSAA
                     MVNLGIYGIVRFDLQLLGPGPRWWGLALLAVGGTSALYGVLQASVAADLKRLLAYSTT
                     ENMGLITLALGAATLFADTGAYGPASIAAAAAMLHMIAHAAFKSLAFMAAGSVLAATG
                     LRDLDLLGGLARRMPATTVFFGVAALGACGLPLGAGFVSEWLLVQSLIHAAPGHDPIV
                     ALTTPLAVGVVALATGLSVAAMTKAFGIGFLARPRSTQAEAAREAPASMRAGMAIAAG
                     ACLVLAVAPLLVAPMVRRAAATLPAAQAVKFTGLGAVVRLPAMSGSIAPGVIAAAVLA
                     AALAVAVLARWRFRRRPAPARLPLWACGAADLTVRMQYTATSFAEPLQRVFGDVLRPD
                     TDIEVTHTAESRYMAERITYRTAVADAIEQRLYTPVVGAVAAMAELLRRAHTGSVHRY
                     LAYGALGVLIVLVVARCT"
     misc_feature    120258..122060
                     /locus_tag="BCG_0116"
                     /note="hydrogenase 4 subunit B; Validated; Region:
                     PRK06521"
                     /db_xref="CDD:235820"
     misc_feature    120441..121283
                     /locus_tag="BCG_0116"
                     /note="NADH-Ubiquinone/plastoquinone (complex I), various
                     chains; Region: Oxidored_q1; pfam00361"
                     /db_xref="CDD:201180"
     gene            122069..123019
                     /gene="hycD"
                     /locus_tag="BCG_0117"
                     /db_xref="GeneID:4695375"
     CDS             122069..123019
                     /gene="hycD"
                     /locus_tag="BCG_0117"
                     /EC_number="1.-.-.-"
                     /codon_start=1
                     /transl_table=11
                     /product="formate hydrogenlyase hycD (FHL)"
                     /protein_id="YP_976220.1"
                     /db_xref="GI:121635997"
                     /db_xref="GeneID:4695375"
                     /translation="MSYLAGAAQIGGVMVGAPLVIGMTRQVRARWEGRAGAGLLQPWR
                     DLLKQLGKQQITPAGTTIVFAAAPVIVAGTTLLIAAIAPLVATGSPLDPSADLFAVVG
                     LLFLGTVALTLAGIDTGTSFGGMGASREITIAALVEPTILLAVFALSIPAGSANLGAL
                     VASTIDHPGHVVSLAGVLAFVALVIVIVAETGRLPVDNPATHLELTMVHEAMVLEYAG
                     PRLALVEWAAGMRLTVLLALLANLFLPWGIAGAAPTALDVLTGVVAVAAKVAILAVLL
                     ATFEVFLAKLRLFRVPELLAGSFLLALLAVTAANFFTVGA"
     misc_feature    122069..122965
                     /gene="hycD"
                     /locus_tag="BCG_0117"
                     /note="Formate hydrogenlyase subunit 4 [Energy production
                     and conversion]; Region: HyfC; COG0650"
                     /db_xref="CDD:223723"
     gene            123030..123692
                     /gene="hycP"
                     /locus_tag="BCG_0118"
                     /db_xref="GeneID:4697265"
     CDS             123030..123692
                     /gene="hycP"
                     /locus_tag="BCG_0118"
                     /EC_number="1.-.-.-"
                     /codon_start=1
                     /transl_table=11
                     /product="hydrogenase hycP"
                     /protein_id="YP_976221.1"
                     /db_xref="GI:121635998"
                     /db_xref="GeneID:4697265"
                     /translation="MSNANFSILVDFAAGGLVLASVLIVWRRDLRAIVRLLAWQGAAL
                     AAIPLLRGIRDNDRALIAVGIAVLALRALVLPWLLARAVGAEAAAQREATPLVNTASS
                     LLITAGLTLTAFAITQPVVNLEPGVTINAVPAAFAVVLIALFVMTTRLHAVSQAAGFL
                     MLDNGIAATAFLLTAGVPLIVELGASLDVLFAVIVIGVLTGRLRRIFGDADLDKLREL
                     RD"
     misc_feature    123036..123689
                     /gene="hycP"
                     /locus_tag="BCG_0118"
                     /note="Hydrogenase 4 membrane component (E) [Energy
                     production and conversion]; Region: HyfE; COG4237"
                     /db_xref="CDD:226688"
     gene            123692..125158
                     /gene="hycQ"
                     /locus_tag="BCG_0119"
                     /db_xref="GeneID:4697267"
     CDS             123692..125158
                     /gene="hycQ"
                     /locus_tag="BCG_0119"
                     /EC_number="1.-.-.-"
                     /note="Differs from Rv0086 by 1aa, T118M"
                     /codon_start=1
                     /transl_table=11
                     /product="hydrogenase hycQ"
                     /protein_id="YP_976222.1"
                     /db_xref="GI:121635999"
                     /db_xref="GeneID:4697267"
                     /translation="MTGLLLAAILAPLAASIASLITGWRRTTATLTALSATTVLACAV
                     AMGFWMGSGAQFGLGGLLRADALTVVMLVVIGIVGTLATAASIGYIDTELAHGHIDGR
                     SARLYGVLTPAFLCATVLAVCANNIGVIWVAIEATTVITAFLVGHRRTRTALEATWKY
                     VVICSVGIAVAFLGTVLLYFAARDSGAAAAGALNLDILAEHAAGLDPGVARLAGGLLL
                     IGYGAKAGLFPFHTWLADAHSQAPAPVSALMSGVLLAVAFSVLIRLRPILDAVSGPAY
                     LRNGLLVVGLATLLVAVLMLTVTGDVKRMLAYSSMEHMGLIAIAAAAGTTLAIAALLL
                     HVLAHGIGKTVLFLAGGQLQAAHDSTAIADITGVMRRSRLIGVSFAVGLIVLLGLPPF
                     AMFASELAIARSLANERLAWVLGAALLLIAIGFTALARNSGRMLLGTPAAGAPAITVP
                     ATAAAALMVGIVVSAALGITAGPLADLLGIAASNVGLP"
     misc_feature    123758..125149
                     /gene="hycQ"
                     /locus_tag="BCG_0119"
                     /note="hydrogenase 4 subunit F; Validated; Region:
                     PRK06458"
                     /db_xref="CDD:235805"
     misc_feature    124061..124894
                     /gene="hycQ"
                     /locus_tag="BCG_0119"
                     /note="NADH-Ubiquinone/plastoquinone (complex I), various
                     chains; Region: Oxidored_q1; pfam00361"
                     /db_xref="CDD:201180"
     gene            125155..126633
                     /gene="hycE"
                     /locus_tag="BCG_0120"
                     /db_xref="GeneID:4697268"
     CDS             125155..126633
                     /gene="hycE"
                     /locus_tag="BCG_0120"
                     /EC_number="1.-.-.-"
                     /note="Differs from Rv0087 by 1aa, I230V"
                     /codon_start=1
                     /transl_table=11
                     /product="formate hydrogenase hycQ (FHL)"
                     /protein_id="YP_976223.1"
                     /db_xref="GI:121636000"
                     /db_xref="GeneID:4697268"
                     /translation="MMSASWLRHRVSERGLIATAEQLWADSFRLALVAAHDDGDSLRV
                     VYLFLAGYPDRRVELEYVVPADNPEIRSLAYLSFPAGRFEREMADLYGIRPVGHPKPR
                     RLVRHAHWPDWHPMRTDAGPAPEFTDTGAFPFLAVEGPGVYEIPVGPVHAGLIEPGHF
                     RFSVAGETIVRLKARLWFVHRGIEKLFHGRPATAAVDLAERISGDTSAAHALAHSLAI
                     EDALGIELPHEIHRLRALIVELERLYNHAADLGALANDVGYSLANAHAQRIRENLLRR
                     NAAVTGHRLLRGAIRAGGVALRALPDTDELAALAVDLAEVATLTLANSVVYDRFAGTA
                     VLHPDDASALGCLGYVARASGLRSDARVEHPTIVLPITEIGAPDGDVLARYTVRRDEF
                     AASAALAQHIVESHTGPIEYAATLHPVGAPSSGIGIVEGWRGTIVHRVEIDVDGRITR
                     AKVVDPSWFNWPALPVAMADTIVPDFPLANKSFNQSYAGNDL"
     misc_feature    125155..125547
                     /gene="hycE"
                     /locus_tag="BCG_0120"
                     /note="Respiratory-chain NADH dehydrogenase, 30 Kd
                     subunit; Region: Complex1_30kDa; cl19197"
                     /db_xref="CDD:267550"
     misc_feature    125557..126630
                     /gene="hycE"
                     /locus_tag="BCG_0120"
                     /note="Ni,Fe-hydrogenase III large subunit [Energy
                     production and conversion]; Region: HycE; COG3261"
                     /db_xref="CDD:225800"
     misc_feature    125581..126606
                     /gene="hycE"
                     /locus_tag="BCG_0120"
                     /note="Respiratory-chain NADH dehydrogenase, 49 Kd
                     subunit; Region: Complex1_49kDa; cl21493"
                     /db_xref="CDD:271913"
     gene            126668..127342
                     /locus_tag="BCG_0121"
                     /db_xref="GeneID:4697266"
     CDS             126668..127342
                     /locus_tag="BCG_0121"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_976224.1"
                     /db_xref="GI:121636001"
                     /db_xref="GeneID:4697266"
                     /translation="MSVYKHAPSRVRLRQTRSTVVKGRSGSLSWRRVRTGDLGLAVWG
                     GREEYRAVKPGTPGIQPKGDMMTVTVVDAGPGRVSRSVEVAAPAAELFAIVADPRRHR
                     ELDGSGTVRGNIKVPAKLVVGSKFSTKMKLFGLPYRITSRVTALKPNELVEWSHPLGH
                     RWRWEFESLSPTLTRVTETFDYHAAGAIKNGLKFYEMTGFAKSNAAGIEATLAKLSDQ
                     YARGRA"
     misc_feature    126896..127309
                     /locus_tag="BCG_0121"
                     /note="Ligand-binding SRPBCC domain of an uncharacterized
                     subfamily of proteins; Region: SRPBCC_7; cd07825"
                     /db_xref="CDD:176867"
     misc_feature    order(126899..126901,126905..126907,126911..126913,
                     126938..126946,126950..126955,126986..126988,
                     127019..127021,127025..127027,127031..127033,
                     127037..127039,127088..127090,127094..127096,
                     127112..127114,127118..127120,127157..127162,
                     127166..127168,127172..127174,127193..127195,
                     127199..127201,127205..127207,127211..127213,
                     127247..127261,127265..127273,127277..127285,
                     127292..127294)
                     /locus_tag="BCG_0121"
                     /note="putative hydrophobic ligand binding site [chemical
                     binding]; other site"
                     /db_xref="CDD:176867"
     gene            127499..128092
                     /locus_tag="BCG_0122"
                     /db_xref="GeneID:4695770"
     CDS             127499..128092
                     /locus_tag="BCG_0122"
                     /EC_number="2.1.1.-"
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase/methylase"
                     /protein_id="YP_976225.1"
                     /db_xref="GI:121636002"
                     /db_xref="GeneID:4695770"
                     /translation="MDQPWNANIHYDALLDAMVPLGTQCVLDVGCGDGLLAARLARRI
                     PYVTAVDIDAPVLRRAQTRFANAPIRWLHADIMTAELPNAGFDAVVSNAALHHIEDTR
                     TALSRLGGLVTPGGTLAVVTFVTPSLRNGLWHLTSWVACGMANRVKGKWEHSAPIKWP
                     PPQTLHELRSHVRALLPGACIRRLLYGRVLVTWRAPV"
     misc_feature    127574..127870
                     /locus_tag="BCG_0122"
                     /note="S-adenosylmethionine-dependent methyltransferases
                     (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes
                     that use S-adenosyl-L-methionine (SAM or AdoMet) as a
                     substrate for methyltransfer, creating the product
                     S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases;
                     cd02440"
                     /db_xref="CDD:100107"
     misc_feature    order(127583..127603,127649..127654,127718..127726,
                     127772..127774)
                     /locus_tag="BCG_0122"
                     /note="S-adenosylmethionine binding site [chemical
                     binding]; other site"
                     /db_xref="CDD:100107"
     gene            128221..128991
                     /locus_tag="BCG_0123"
                     /db_xref="GeneID:4695984"
     CDS             128221..128991
                     /locus_tag="BCG_0123"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_976226.1"
                     /db_xref="GI:121636003"
                     /db_xref="GeneID:4695984"
                     /translation="MAKNQNRIRNRWELITCGLGGHVTYAPDDAALAARLRASTGLGE
                     VWRCLRCGDFALGGPQGRGAPEDAPLIMRGKALRQAIIIRALGVERLVRALVLALAAW
                     AVWEFRGARGAIQATLDRDLPVLRAAGFKVDQMTVIHALEKALAAKPSTLALITGMLA
                     AYAVLQAVEGVGLWLLKRWGEYFAVVATSIFLPLEVHDLAKGITTTRVVTFSINVAAV
                     VYLLISKRLFGVRGGRKAYDVERRGEQLLDLERAAMLT"
     misc_feature    128473..128934
                     /locus_tag="BCG_0123"
                     /note="Predicted membrane protein [Function unknown];
                     Region: COG3305"
                     /db_xref="CDD:225842"
     gene            129425..130192
                     /gene="mtn"
                     /locus_tag="BCG_0124"
                     /db_xref="GeneID:4697519"
     CDS             129425..130192
                     /gene="mtn"
                     /locus_tag="BCG_0124"
                     /EC_number="3.2.2.16"
                     /EC_number="3.2.2.9"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional MTA/SAH nucleosidase mtn"
                     /protein_id="YP_976227.1"
                     /db_xref="GI:121636004"
                     /db_xref="GeneID:4697519"
                     /translation="MAVTVGVICAIPQELAYLRGVLVDAKRQQVAQILFDSGQLDAHR
                     VVLAAAGMGKVNTGLTATLLADRFGCRTIVFTGVAGGLDPELCIGDIVIADRVVQHDF
                     GLLTDERLRPYQPGHIPFIEPTERLGYPVDPAVIDRVKHRLDGFTLAPLSTAAGGGGR
                     QPRIYYGTILTGDQYLHCERTRNRLHHELGGMAVEMEGGAVAQICASFDIPWLVIRAL
                     SDLAGADSGVDFNRFVGEVAASSARVLLRLLPVLTAC"
     misc_feature    129434..130141
                     /gene="mtn"
                     /locus_tag="BCG_0124"
                     /note="Phosphorylase superfamily; Region: PNP_UDP_1;
                     cl00303"
                     /db_xref="CDD:260338"
     gene            130324..132609
                     /gene="ctpA"
                     /locus_tag="BCG_0125"
                     /db_xref="GeneID:4697738"
     CDS             130324..132609
                     /gene="ctpA"
                     /locus_tag="BCG_0125"
                     /EC_number="3.6.3.-"
                     /note="Differs from Rv0092 by 1aa, A3T"
                     /codon_start=1
                     /transl_table=11
                     /product="cation transporter p-type atpase A ctpA"
                     /protein_id="YP_976228.1"
                     /db_xref="GI:121636005"
                     /db_xref="GeneID:4697738"
                     /translation="MTAAVTGEHHASVQRIQLRISGMSCSACAHRVESTLNKLPGVRA
                     AVNFGTRVATIDTSEAVDAAALCQAVRRAGYQADLCTDDGRSASDPDADHARQLLIRL
                     AIAAVLFVPVADLSVMFGVVPATRFTGWQWVLSALALPVVTWAAWPFHRVAMRNARHH
                     AASMETLISVGITAATIWSLYTVFGNHSPIERSGIWQALLGSDAIYFEVAAGVTVFVL
                     VGRYFEARAKSQAGSALRALAALSAKEVAVLLPDGSEMVIPADELKEQQRFVVRPGQI
                     VAADGLAVDGSAAVDMSAMTGEAKPTRVRPGGQVIGGTTVLDGRLIVEAAAVGADTQF
                     AGMVRLVEQAQAQKADAQRLADRISSVFVPAVLVIAALTAAGWLIAGGQPDRAVSAAL
                     AVLVIACPCALGLATPTAMMVASGRGAQLGIFLKGYKSLEATRAVDTVVFDKTGTLTT
                     GRLQVSAVTAAPGWEADQVLALAATVEAASEHSVALAIAAATTRRDAVTDFRAIPGRG
                     VSGTVSGRAVRVGKPSWIGSSSCHPNMRAARRHAESLGETAVFVEVDGEPCGVIAVAD
                     AVKDSARDAVAALADRGLRTMLLTGDNPESAAAVATRVGIDEVIADILPEGKVDVIEQ
                     LRDRGHVVAMVGDGINDGPALARADLGMAIGRGTDVAIGAADIILVRDHLDVVPLALD
                     LARATMRTVKLNMVWAFGYNIAAIPVAAAGLLNPLVAGAAMAFSSFFVVSNSLRLRKF
                     GRYPLGCGTVGGPQMTAPSSA"
     misc_feature    130363..132549
                     /gene="ctpA"
                     /locus_tag="BCG_0125"
                     /note="Cation transport ATPase [Inorganic ion transport
                     and metabolism]; Region: ZntA; COG2217"
                     /db_xref="CDD:225127"
     misc_feature    130372..130554
                     /gene="ctpA"
                     /locus_tag="BCG_0125"
                     /note="Heavy-metal-associated domain (HMA) is a conserved
                     domain of approximately 30 amino acid residues found in a
                     number of proteins that transport or detoxify heavy
                     metals, for example, the CPx-type heavy metal ATPases and
                     copper chaperones. HMA domain...; Region: HMA; cd00371"
                     /db_xref="CDD:238219"
     misc_feature    order(130390..130398,130405..130407)
                     /gene="ctpA"
                     /locus_tag="BCG_0125"
                     /note="metal-binding site [ion binding]"
                     /db_xref="CDD:238219"
     misc_feature    130960..131622
                     /gene="ctpA"
                     /locus_tag="BCG_0125"
                     /note="E1-E2 ATPase; Region: E1-E2_ATPase; pfam00122"
                     /db_xref="CDD:249606"
     misc_feature    131989..132378
                     /gene="ctpA"
                     /locus_tag="BCG_0125"
                     /note="Soluble P-type ATPase [General function prediction
                     only]; Region: COG4087"
                     /db_xref="CDD:226572"
     misc_feature    132091..132093
                     /gene="ctpA"
                     /locus_tag="BCG_0125"
                     /note="motif II; other site"
                     /db_xref="CDD:119389"
     gene            complement(132556..133404)
                     /locus_tag="BCG_0126c"
                     /db_xref="GeneID:4697724"
     CDS             complement(132556..133404)
                     /locus_tag="BCG_0126c"
                     /note="Differs from Rv0093c by 1aa, R22C"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_976229.1"
                     /db_xref="GI:121636006"
                     /db_xref="GeneID:4697724"
                     /translation="MLAQATTAGSFNHHASTVLQGRRGVPAAMWSEPAGAIRRHCATI
                     DGMDCEVAREALSARLDGERAPVPSARVDEHLGECSACRAWFTQVASQAGDLRRLAES
                     RPVVPPVGRLGIRRAPRRQHSPMTWRRWALLCVGIAQIALGTVQGFGLDVGLTHQHPT
                     GAGTHLLNESTSWSIALGVIMVGAALWPSAAAGLAGVLTAFVAILTGYVIVDALSGAV
                     STTRILTHLPVVIGAVLAIMVWRSASGPRPRPDAVAAEPDIVLPDNASRGRRRGHLWP
                     TDGSAA"
     misc_feature    complement(132559..133269)
                     /locus_tag="BCG_0126c"
                     /note="Predicted integral membrane protein [Function
                     unknown]; Region: COG5660"
                     /db_xref="CDD:227947"
     misc_feature    complement(133153..133260)
                     /locus_tag="BCG_0126c"
                     /note="Putative zinc-finger; Region: zf-HC2; pfam13490"
                     /db_xref="CDD:257814"
     gene            complement(133451..134404)
                     /locus_tag="BCG_0127c"
                     /db_xref="GeneID:4696049"
     CDS             complement(133451..134404)
                     /locus_tag="BCG_0127c"
                     /note="Differs from Rv0094c by 3aa, D256E, W296R, K315E"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_976230.1"
                     /db_xref="GI:121636007"
                     /db_xref="GeneID:4696049"
                     /translation="MSTRQAAEADLAGKAAQYRPDELARYAQRVMDWLHPDGDLTDTE
                     RARKRGITLSNQQYDGMSRLSGYLTPQARATFEAVLAKLAAPGATNPDDHTPVIDTTP
                     DAAAIDRDTRSQAQRNHDGLLAGLRALIASGELGQHNGLPVSIVVTTTLTDLQTGAGK
                     GFTGGGTLLPMADVIRMTSHAHHYSPASGRYPQAIFDHGTPLALYHTKRLASPAQRIM
                     LFANDRGCTKPGCDAPAYHSQAHHVTGWTSTGRTDITDLTLACDPDNRLAEKGWTTRK
                     NTHGHTEWLPPPHLDHGQPWTNTFHHPERFLHNQDDDDKPD"
     misc_feature    complement(133736..>134404)
                     /locus_tag="BCG_0127c"
                     /note="Domain of unknown function (DUF222); Region:
                     DUF222; pfam02720"
                     /db_xref="CDD:251494"
     misc_feature    complement(133601..133762)
                     /locus_tag="BCG_0127c"
                     /note="HNH nucleases; HNH endonuclease signature which is
                     found in viral, prokaryotic, and eukaryotic proteins. The
                     alignment includes members of the large group of homing
                     endonucleases, yeast intron 1 protein, MutS, as well as
                     bacterial colicins, pyocins, and...; Region: HNHc;
                     cd00085"
                     /db_xref="CDD:238038"
     misc_feature    complement(order(133610..133612,133619..133624,
                     133634..133639,133670..133672,133676..133684,
                     133688..133690))
                     /locus_tag="BCG_0127c"
                     /note="active site"
                     /db_xref="CDD:238038"
     repeat_region   complement(133454..134957)
                     /note="REP-2, len: 1504 nt. Equivalent to REP, len: 1503
                     nt, from Mycobacterium tuberculosis strain H37Rv, (97.0%
                     identity in 1504 nt overlap). REP251, member of REP13E12
                     family"
                     /rpt_family="REP"
     gene            complement(134175..134957)
                     /locus_tag="BCG_0128c"
                     /db_xref="GeneID:4698785"
     CDS             complement(134175..134957)
                     /locus_tag="BCG_0128c"
                     /note="In Mycobacterium tuberculosis strain H37Rv, Rv0095c
                     and Rv1588 exist as separate genes in their respective
                     positions. In Mycobacterium bovis BCG Pasteur, and
                     Mycobacterium bovis, a 73 bp substitution leads to a
                     single combined gene. Differs from Rv0095c by 5aa, E57D,
                     T70S, V85A, V91G, A92Q"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_976231.1"
                     /db_xref="GI:121636008"
                     /db_xref="GeneID:4698785"
                     /translation="MRYLPVSTRRIWVNPLCHFSFTVISGALFVSARRYDSNMLANSR
                     EELVEVFDALDAELDRLDEVSFEVLTTPERLRSLERLECLVRRLPAVGHTLINQLDTQ
                     ASEEELGGTLCCALANRLRITKPDAALRIADAADLGPRRALTGEPLAPQLTATATAQR
                     QGLIGEAHIKVIRALFRPPARRGGCVHPPGRRSRPGRQSRSISSRRAGPLRPAGHGLA
                     TPRRRPHRHRTRPQTRHHPEQPAIRRHVTAKWLPDPPSAGHL"
     misc_feature    complement(<134436..134738)
                     /locus_tag="BCG_0128c"
                     /note="Domain of unknown function (DUF222); Region:
                     DUF222; pfam02720"
                     /db_xref="CDD:251494"
     gene            135066..136457
                     /gene="PPE1"
                     /locus_tag="BCG_0129"
                     /db_xref="GeneID:4697111"
     CDS             135066..136457
                     /gene="PPE1"
                     /locus_tag="BCG_0129"
                     /note="Differs from Rv0096 by 1aa, W182R"
                     /codon_start=1
                     /transl_table=11
                     /product="PPE family protein"
                     /protein_id="YP_976232.1"
                     /db_xref="GI:121636009"
                     /db_xref="GeneID:4697111"
                     /translation="MAIPPEVHSGLLSAGCGPGSLLVAAQQWQELSDQYALACAELGQ
                     LLGEVQASSWQGTAATQYVAAHGPYLAWLEQTAINSAVTAAQHVAAAAAYCSALAAMP
                     TPAELAANHAIHGVLIATNFFGINTVPIALNEADYVRMWLQAADTMAAYQAVADAATV
                     AVPSTQPAPPIRAPGGDAADTWLDVLSSIGQLIRDILDFIANPYKYFLEFFEQFGFSP
                     AVTVVLALVALQLYDFLWYPYYASYGLLLLPFFTPTLSALTALSALIHLLNLPPAGLL
                     PIAAALGPGDQWGANLAVAVTPATAAVPGGSPPTSNPAPAAPSSNSVGSASAAPGISY
                     AVPGLAPPGVSSGPKAGTKSPDTAADTLATAGAARPGLARAHRRKRSESGVGIRGYRD
                     EFLDATATVDAATDVPAPANAAGSQGAGTLGFAGTAPTTSGAAAGMVQLSSHSTSTTV
                     PLLPTTWTTDAEQ"
     misc_feature    135066..136445
                     /gene="PPE1"
                     /locus_tag="BCG_0129"
                     /note="PPE-repeat proteins [Cell motility and secretion];
                     Region: COG5651"
                     /db_xref="CDD:227938"
     misc_feature    135069..135509
                     /gene="PPE1"
                     /locus_tag="BCG_0129"
                     /note="PPE family; Region: PPE; pfam00823"
                     /db_xref="CDD:250158"
     misc_feature    <135978..136178
                     /gene="PPE1"
                     /locus_tag="BCG_0129"
                     /note="Gammaherpesvirus capsid protein; Region:
                     Herpes_capsid; pfam06112"
                     /db_xref="CDD:147982"
     gene            136476..137345
                     /locus_tag="BCG_0130"
                     /db_xref="GeneID:4696160"
     CDS             136476..137345
                     /locus_tag="BCG_0130"
                     /EC_number="1.-.-.-"
                     /codon_start=1
                     /transl_table=11
                     /product="oxidoreductase"
                     /protein_id="YP_976233.1"
                     /db_xref="GI:121636010"
                     /db_xref="GeneID:4696160"
                     /translation="MTLKVKGEGLGAQVTGVDPKNLDDITTDEIRDIVYTNKLVVLKD
                     VHPSPREFIKLGRIIGQIVPYYEPMYHHEDHPEIFVSSTEEGQGVPKTGAFWHIDYMF
                     MPEPFAFSMVLPLAVPGHDRGTYFIDLARVWQSLPAAKRDPARGTVSTHDPRRHIKIR
                     PSDVYRPIGEVWDEINRTTPPIKWPTVIRHPKTGQEILYICATGTTKIEDKDGNPVDP
                     EVLQELMAATGQLDPEYQSPFIHTQHYQVGDIILWDNRVLMHRAKHGSAAGTLTTYRL
                     TMLDGLKTPGYAA"
     misc_feature    136476..137339
                     /locus_tag="BCG_0130"
                     /note="Probable taurine catabolism dioxygenase [Secondary
                     metabolites biosynthesis, transport, and catabolism];
                     Region: TauD; COG2175"
                     /db_xref="CDD:225086"
     misc_feature    136494..137306
                     /locus_tag="BCG_0130"
                     /note="Taurine catabolism dioxygenase TauD, TfdA family;
                     Region: TauD; pfam02668"
                     /db_xref="CDD:251459"
     gene            137342..137893
                     /locus_tag="BCG_0131"
                     /db_xref="GeneID:4697693"
     CDS             137342..137893
                     /locus_tag="BCG_0131"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_976234.1"
                     /db_xref="GI:121636011"
                     /db_xref="GeneID:4697693"
                     /translation="MSHTDLTPCTRVLASSGTVPIAEELLARVLEPYSCKGCRYLIDA
                     QYSATEDSVLAYGNFTIGESAYIRSTGHFNAVELILCFNQLAYSAFAPAVLNEEIRVL
                     RGWSIDDYCQHQLSSMLIRKASSRFRKPLNPQKFSARLLCRDLQVIERTWRYLKVPCV
                     IEFWDENGGAASGEIELAALNIP"
     misc_feature    137423..137878
                     /locus_tag="BCG_0131"
                     /note="FcoT-like thioesterase domain; Region: FcoT;
                     pfam10862"
                     /db_xref="CDD:151311"
     gene            137898..139520
                     /gene="fadD10"
                     /locus_tag="BCG_0132"
                     /db_xref="GeneID:4697870"
     CDS             137898..139520
                     /gene="fadD10"
                     /locus_tag="BCG_0132"
                     /EC_number="2.3.1.86"
                     /note="activates fatty acids by binding to coenzyme A"
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-CoA synthetase"
                     /protein_id="YP_976235.1"
                     /db_xref="GI:121636012"
                     /db_xref="GeneID:4697870"
                     /translation="MGGKKFQAMPQLPSTVLDRVFEQARQQPEAIALRRCDGTSALRY
                     RELVAEVGGLAADLRAQSVSRGSRVLVISDNGPETYLSVLACAKLGAIAVMADGNLPI
                     AAIERFCQITDPAAALVAPGSKMASSAVPEALHSIPVIAVDIAAVTRESEHSLDAASL
                     AGNADQGSEDPLAMIFTSGTTGEPKAVLLANRTFFAVPDILQKEGLNWVTWVVGETTY
                     SPLPATHIGGLWWILTCLMHGGLCVTGGENTTSLLEILTTNAVATTCLVPTLLSKLVS
                     ELKSANATVPSLRLVGYGGSRAIAADVRFIEATGVRTAQVYGLSETGCTALCLPTDDG
                     SIVKIEAGAVGRPYPGVDVYLAATDGIGPTAPGAGPSASFGTLWIKSPANMLGYWNNP
                     ERTAEVLIDGWVNTGDLLERREDGFFYIKGRSSEMIICGGVNIAPDEVDRIAEGVSGV
                     REAACYEIPDEEFGALVGLAVVASAELDESAARALKHTIAARFRRESEPMARPSTIVI
                     VTDIPRTQSGKVMRASLAAAATADKARVVVRG"
     misc_feature    137898..139517
                     /gene="fadD10"
                     /locus_tag="BCG_0132"
                     /note="acyl-CoA synthetase; Validated; Region: PRK05857"
                     /db_xref="CDD:180293"
     misc_feature    138405..139460
                     /gene="fadD10"
                     /locus_tag="BCG_0132"
                     /note="Adenylate forming domain, Class I; Region:
                     AFD_class_I; cd04433"
                     /db_xref="CDD:213270"
     misc_feature    order(138417..138419,138426..138443,138447..138452)
                     /gene="fadD10"
                     /locus_tag="BCG_0132"
                     /note="acyl-activating enzyme (AAE) consensus motif; other
                     site"
                     /db_xref="CDD:213270"
     misc_feature    order(138426..138428,138777..138782,138840..138857,
                     139119..139121,139155..139157,139164..139166,
                     139197..139199,139452..139454)
                     /gene="fadD10"
                     /locus_tag="BCG_0132"
                     /note="AMP binding site [chemical binding]; other site"
                     /db_xref="CDD:213270"
     misc_feature    order(138426..138428,138558..138563,138696..138698,
                     138702..138707,138714..138716,138777..138782,
                     138840..138857,139119..139121,139155..139157,
                     139164..139166,139188..139199,139395..139397)
                     /gene="fadD10"
                     /locus_tag="BCG_0132"
                     /note="active site"
                     /db_xref="CDD:213270"
     misc_feature    order(138558..138560,138702..138707,138714..138716,
                     138777..138779,139188..139196,139377..139379,
                     139395..139397)
                     /gene="fadD10"
                     /locus_tag="BCG_0132"
                     /note="CoA binding site [chemical binding]; other site"
                     /db_xref="CDD:213270"
     gene            139525..139761
                     /locus_tag="BCG_0133"
                     /db_xref="GeneID:4695648"
     CDS             139525..139761
                     /locus_tag="BCG_0133"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_976236.1"
                     /db_xref="GI:121636013"
                     /db_xref="GeneID:4695648"
                     /translation="MRDRILAAVCDVLYIDEADLIDGDETDLRDLGLDSVRFVLLMKQ
                     LGVNRQSELPSRLAANPSIAGWLRELEAVCTEFG"
     misc_feature    139531..139734
                     /locus_tag="BCG_0133"
                     /note="Phosphopantetheine attachment site; Region:
                     PP-binding; pfam00550"
                     /db_xref="CDD:249951"
     gene            139743..147281
                     /gene="nrp"
                     /locus_tag="BCG_0134"
                     /db_xref="GeneID:4696972"
     CDS             139743..147281
                     /gene="nrp"
                     /locus_tag="BCG_0134"
                     /EC_number="6.-.-.-"
                     /codon_start=1
                     /transl_table=11
                     /product="peptide synthetase nrp"
                     /protein_id="YP_976237.1"
                     /db_xref="GI:121636014"
                     /db_xref="GeneID:4696972"
                     /translation="MHRVRLSRSQRNLYNGVRQDNNPALYLIGKSYRFRRLELARFLA
                     ALHATVLDNPVQLCVLENSGADYPDLVPRLRFGDIVRVGSADEHLQSTWCSGILGKPL
                     VRHTVHTDPNGYVTGLDVHTHHILLDGGATGTIEADLARYLTTDPAGETPSVGAGLAK
                     LREAHRRETAKVEESRGRLSAVVQRELADEAYHGGHGHSVSDAPGTAAKGVLHESATI
                     CGNAFDAILTLSEAQRVPLNVLVAAAAVAVDASLRQNTETLLVHTVDNRFGDSDLNVA
                     TCLVNSVAQTVRFPPFASVSDVVRTLDRGYVKAVRRRWLREEHYRRMYLAINRTSHVE
                     ALTLNFIREPCAPGLRPFLSEVPIATDIGPVEGMTVASVLDEEQRTLNLAIWNRADLP
                     ACKTHPKVAERIAAALESMAAMWDRPIAMIVNDWFGIGPDGTRCQGDWPARQPSTPAW
                     FLDSARGVHQFLGRRRFVYPWVAWLVQRGAAPGDVLVFTDDDTDKTIDLLIACHLAGC
                     GYSVCDTADEISVRTNAITEHGDGILVTVVDVAATQLAVVGHDELRKVVDERVTQVTH
                     DALLATKTAYIMPTSGTTGQPKLVRISHGSLAVFCDAISRAYGWGAHDTVLQCAPLTS
                     DISVEEIFGGAACGARLVRSAAMKTGDLAALVDDLVARETTIVDLPTAVWQLLCADGD
                     AIDAIGRSRLRQIVIGGEAIRCSAVDKWLESAASQGISLLSSYGPTEATVVATFLPIV
                     CDQTTMDGALLRLGRPILPNTVFLAFGEVVIVGDLVADGYLGIDGDGFGTVTAADGSR
                     RRAFATGDRVTVDAEGFPVFSGRKDAVVKISGKRVDIAEVTRRIAEDPAVSDVAVELH
                     SGSLGVWFKSQRTREGEQDAAAATRIRLVLVSLGVSSFFVVGVPNIPRKPNGKIDSDN
                     LPRLPQWSAAGLNTAETGQRAAGLSQIWSRQLGRAIGPDSSLLGEGIGSLDLIRILPE
                     TRRYLGWRLSLLDLIGADTAANLADYAPTPDAPTGEDRFRPLVAAQRPAAIPLSFAQR
                     RLWFLDQLQRPAPVYNMAVALRLRGYLDTEALGAAVADVVGRHESLRTVFPAVDGVPR
                     QLVIEARRADLGCDIVDATAWPADRLQRAIEEAARHSFDLATEIPLRTWLFRIADDEH
                     VLVAVAHHIAADGWSVAPLTADLSAAYASRCAGRAPDWAPLPVQYVDYTLWQREILGD
                     LDDSDSPIAAQLAYWENALAGMPERLRLPTARPYPPVADQRGASLVVDWPASVQQQVR
                     RIARQHNATSFMVVAAGLAVLLSKLSGSPDVAVGFPIAGRSDPALDNLVGFFVNTLVL
                     RVNLAGDPSFAELLGQVRARSLAAYENQDVPFEVLVDRLKPTRAMTHHPLIQVMLAWQ
                     DNPVGQLNLGDLQATPMPIDTRTARMDLVFSLAERFSEGSEPAGIGGAVEYRTDVFEA
                     QAIDVLIERLRKVLVAVAAAPERTVSSIDALDGTERARLDEWGNRAVLTAPAPTPVSI
                     PQMLAAQVARIPEAEAVCCGDASMTYRELDEASNRLAHRLAGCGAGPGECVALLFERC
                     APAVVAMVAVLKTGAAYLPIDPANPPPRVAFMLGDAVPVAAVTTAGLRSRLAGHDLPI
                     IDVVDALAAYPGTPPPMPAAVNLAYILYTSGTTGEPKGVGITHRNVTRLFASLPARLS
                     AAQVWSQCHSYGFDASAWEIWGALLGGGRLVIVPESVAASPNDFHGLLVAEHVSVLTQ
                     TPAAVAMLPTQGLESVALVVAGEACPAALVDRWAPGRVMLNAYGPTETTICAAISAPL
                     RPGSGMPPIGVPVSGAALFVLDSWLRPVPAGVAGELYIAGAGVGVGYWRRAGLTASRF
                     VACPFGGSGARMYRTGDLVCWRADGQLEFLGRTDDQVKIRGYRIELGEVATALAELAG
                     VGQAVVIAREDRPGDKRLVGYATEIAPGAVDPAGLRAQLAQRLPGYLVPAAVVVIDAL
                     PLTVNGKLDHRALPAPEYGDTNGYRAPAGPVEKTVAGIFARVLGLERVGVDDSFFELG
                     GDSLAAMRVIAAINTTLNADLPVRALLHASSTRGLSQLLGRDARPTSDPRLVSVHGDN
                     PTEVHASDLTLDRFIDADTLATAVNLPGPSPELRTVLLTGATGFLGRYLVLELLRRLD
                     VDGRLICLVRAESDEDARRRLEKTFDSGDPELLRHFKELAADRLEVVAGDKSEPDLGL
                     DQPMWRRLAETVDLIVDSAAMVNAFPYHELFGPNVAGTAELIRIALTTKLKPFTYVST
                     ADVGAAIEPSAFTEDADIRVISPTRTVDGGWAGGYGTSKWAGEVLLREANDLCALPVA
                     VFRCGMILADTSYAGQLNMSDWVTRMVLSLMATGIAPRSFYEPDSEGNRQRAHFDGLP
                     VTFVAEAIAVLGARVAGSSLAGFATYHVMNPHDDGIGLDEYVDWLIEAGYPIRRIDDF
                     AEWLQRFEASLGALPDRQRRHSVLPMLLASNSQRLQPLKPTRGCSAPTDRFRAAVRAA
                     KVGSDKDNPDIPHVSAPTIINYVTNLQLLGLL"
     misc_feature    141159..>141608
                     /gene="nrp"
                     /locus_tag="BCG_0134"
                     /note="Adenylate forming domain, Class I; Region:
                     AFD_class_I; cl17068"
                     /db_xref="CDD:266508"
     misc_feature    141171..142301
                     /gene="nrp"
                     /locus_tag="BCG_0134"
                     /note="amino acid adenylation domain; Region:
                     AA-adenyl-dom; TIGR01733"
                     /db_xref="CDD:233550"
     misc_feature    141414..142475
                     /gene="nrp"
                     /locus_tag="BCG_0134"
                     /note="Adenylate forming domain, Class I; Region:
                     AFD_class_I; cl17068"
                     /db_xref="CDD:266508"
     misc_feature    order(141471..141473,141480..141497,141501..141506)
                     /gene="nrp"
                     /locus_tag="BCG_0134"
                     /note="acyl-activating enzyme (AAE) consensus motif; other
                     site"
                     /db_xref="CDD:213270"
     misc_feature    order(141471..141473,141480..141497,141501..141506)
                     /gene="nrp"
                     /locus_tag="BCG_0134"
                     /note="acyl-activating enzyme (AAE) consensus motif; other
                     site"
                     /db_xref="CDD:213270"
     misc_feature    order(141480..141482,141834..141839,141909..141926,
                     142158..142160,142194..142196,142203..142205,
                     142236..142238,142467..142469)
                     /gene="nrp"
                     /locus_tag="BCG_0134"
                     /note="AMP binding site [chemical binding]; other site"
                     /db_xref="CDD:213270"
     misc_feature    order(141480..141482,141600..141605,141750..141752,
                     141756..141761,141768..141770,141834..141839,
                     141909..141926,142158..142160,142194..142196,
                     142203..142205,142227..142238,142407..142409)
                     /gene="nrp"
                     /locus_tag="BCG_0134"
                     /note="active site"
                     /db_xref="CDD:213270"
     misc_feature    order(141600..141602,141756..141761,141768..141770,
                     141834..141836,142227..142235,142407..142409)
                     /gene="nrp"
                     /locus_tag="BCG_0134"
                     /note="CoA binding site [chemical binding]; other site"
                     /db_xref="CDD:213270"
     misc_feature    142554..142736
                     /gene="nrp"
                     /locus_tag="BCG_0134"
                     /note="Phosphopantetheine attachment site; Region:
                     PP-binding; pfam00550"
                     /db_xref="CDD:249951"
     misc_feature    142809..143714
                     /gene="nrp"
                     /locus_tag="BCG_0134"
                     /note="Condensation domain; Region: Condensation;
                     pfam00668"
                     /db_xref="CDD:250042"
     misc_feature    143499..145439
                     /gene="nrp"
                     /locus_tag="BCG_0134"
                     /note="Non-ribosomal peptide synthetase modules and
                     related proteins [Secondary metabolites biosynthesis,
                     transport, and catabolism]; Region: EntF; COG1020"
                     /db_xref="CDD:223951"
     misc_feature    143778..144080
                     /gene="nrp"
                     /locus_tag="BCG_0134"
                     /note="HxxPF-repeated domain; Region: HxxPF_rpt;
                     pfam13745"
                     /db_xref="CDD:258038"
     misc_feature    144258..145655
                     /gene="nrp"
                     /locus_tag="BCG_0134"
                     /note="The adenylation domain of nonribosomal peptide
                     synthetases (NRPS); Region: A_NRPS; cd05930"
                     /db_xref="CDD:213296"
     misc_feature    order(144648..144650,144657..144674,144678..144683)
                     /gene="nrp"
                     /locus_tag="BCG_0134"
                     /note="acyl-activating enzyme (AAE) consensus motif; other
                     site"
                     /db_xref="CDD:213296"
     misc_feature    order(144657..144662,144984..144989,145041..145058,
                     145119..145121,145317..145319,145353..145355,
                     145362..145364,145635..145637)
                     /gene="nrp"
                     /locus_tag="BCG_0134"
                     /note="AMP binding site [chemical binding]; other site"
                     /db_xref="CDD:213296"
     misc_feature    145713..145907
                     /gene="nrp"
                     /locus_tag="BCG_0134"
                     /note="Phosphopantetheine attachment site; Region:
                     PP-binding; pfam00550"
                     /db_xref="CDD:249951"
     misc_feature    146064..147278
                     /gene="nrp"
                     /locus_tag="BCG_0134"
                     /note="Putative dehydrogenase domain of multifunctional
                     non-ribosomal peptide synthetases and related enzymes
                     [Secondary metabolites biosynthesis, transport, and
                     catabolism]; Region: COG3320"
                     /db_xref="CDD:225857"
     misc_feature    146067..147017
                     /gene="nrp"
                     /locus_tag="BCG_0134"
                     /note="extended (e) SDRs, subgroup 1; Region: SDR_e1;
                     cd05235"
                     /db_xref="CDD:187546"
     misc_feature    order(146082..146084,146088..146099,146163..146171,
                     146364..146372,146409..146411,146478..146486,
                     146589..146591,146601..146603,146670..146681)
                     /gene="nrp"
                     /locus_tag="BCG_0134"
                     /note="putative NAD(P) binding site [chemical binding];
                     other site"
                     /db_xref="CDD:187546"
     misc_feature    order(146412..146414,146484..146486,146589..146591,
                     146601..146603)
                     /gene="nrp"
                     /locus_tag="BCG_0134"
                     /note="active site"
                     /db_xref="CDD:187546"
     misc_feature    order(146484..146486,146589..146591,146676..146678,
                     146724..146726,146757..146759)
                     /gene="nrp"
                     /locus_tag="BCG_0134"
                     /note="putative substrate binding site [chemical binding];
                     other site"
                     /db_xref="CDD:187546"
     gene            147456..149441
                     /locus_tag="BCG_0135"
                     /db_xref="GeneID:4699183"
     CDS             147456..149441
                     /locus_tag="BCG_0135"
                     /codon_start=1
                     /transl_table=11
                     /product="integral membrane protein"
                     /protein_id="YP_976238.1"
                     /db_xref="GI:121636015"
                     /db_xref="GeneID:4699183"
                     /translation="MGTHGATKSATSAVPTPRSNSMAMVRLAIGLLGVCAVVAAFGLV
                     SGARRYAEAGNPYPGAFVSVAEPVGFFAASLAGALCLGALIHVVMTAKPEPDGLIDAA
                     AFRIHLLAERVSGLWLGLAATMVVIQAAHDTGVGPARLLASGALSDSVAASEMARGWI
                     VAAICALVVATALRLYTRWLGHVVLLVPTVLAVVATAVTGNPGQGPDHDYATSAAIVF
                     AVAFATLTGLKIAAALAGTTPSRAVLVTQVTCGALALAYGAMLLYLFIPGWAVDSDFA
                     RLGLLAGVILTSVWLFDCWRLLVRPPHAGRRRGGGSGAALAMMAAMASIAAMAVMTAP
                     RFLTHAFTAWDVFLGYELPQPPTIARVLTVWRFDSLIGAAGVVLAIGYAAGFAALRRR
                     GNSWPVGRLIAWLTGCAALVFTSGSGVRAYGSAMFSVHMAEHMTLNMFIPVLLVLGGP
                     VTLALRVLPVTGDGRPPGAREWLTWLLHSRVTTFLSHPITAFVLFVASPYIVYFTPLF
                     DTFVRYHWGHEFMAIHFLVVGYLFYWAIIGIDPGPRRLPYPGRIGLLFAVMPFHAFFG
                     IALMTMSSTVGATFYRSVNLPWLSSIIADQHLGGGIAWSLTELPVIMVIVALVTQWAR
                     QDRRVASREDRHADSDYADDELEAYNAMLRELSRMRR"
     misc_feature    148521..149438
                     /locus_tag="BCG_0135"
                     /note="Predicted membrane protein [Function unknown];
                     Region: COG3336"
                     /db_xref="CDD:225873"
     gene            complement(149657..151915)
                     /gene="ctpB"
                     /locus_tag="BCG_0136c"
                     /db_xref="GeneID:4697602"
     CDS             complement(149657..151915)
                     /gene="ctpB"
                     /locus_tag="BCG_0136c"
                     /EC_number="3.6.3.-"
                     /note="Differs from Rv0103c by 1aa, S22L"
                     /codon_start=1
                     /transl_table=11
                     /product="cation-transporter P-type atpase B ctpB"
                     /protein_id="YP_976239.1"
                     /db_xref="GI:121636016"
                     /db_xref="GeneID:4697602"
                     /translation="MAAPVVGDADLQSVRRIRLDVSGMSCAACASRVETKLNKIPGVR
                     ASVNFATRVATIDAVGMAADELCGVVEKAGYHAAPHTETTVLDKRTKDPDGAHARRLL
                     RRLLVAAVLFVPLADLSTLFAIVPSARVPGWGYILTALAAPVVTWAAWPFHSVALRNA
                     RHRTTSMETLISVGIVAATAWSLSSVFGDQPPREGSGIWRAILNSDSIYLEVAAGVTV
                     FVLAGRYFEARAKSKAGSALRALAELGAKNVAVLLPDGAELVIPASELKKRQRFVTRP
                     GETIAADGVVVDGSAAIDMSAMTGEAKPVRAYPAASVVGGTVVMDGRLVIEATAVGAD
                     TQFAAMVRLVEQAQTQKARAQRLADHIAGVFVPVVFVIAGLAGAAWLVSGAGADRAFS
                     VTLGVLVIACPCALGLATPTAMMVASGRGAQLGIFIKGYRALETIRSIDTVVFDKTGT
                     LTVGQLAVSTVTMAGSGTSERDREEVLGLAAAVESASEHAMAAAIVAASPDPGPVNGF
                     VAVAGCGVSGEVGGHHVEVGKPSWITRTTPCHDAALVSARLDGESRGETVVFVSVDGV
                     VRAALTIADTLKDSAAAAVAALRSRGLRTILLTGDNRAAADAVAAQVGIDSAVADMLP
                     EGKVDVIQRLREEGHTVAMVGDGINDGPALVGADLGLAIGRGTDVALGAADIILVRDD
                     LNTVPQALDLARATMRTIRMNMIWAFGYNVAAIPIAAAGLLNPLIAGAAMAFSSFFVV
                     SNSLRLRNFGAQ"
     misc_feature    complement(149669..151873)
                     /gene="ctpB"
                     /locus_tag="BCG_0136c"
                     /note="Cation transport ATPase [Inorganic ion transport
                     and metabolism]; Region: ZntA; COG2217"
                     /db_xref="CDD:225127"
     misc_feature    complement(151682..151861)
                     /gene="ctpB"
                     /locus_tag="BCG_0136c"
                     /note="Heavy-metal-associated domain (HMA) is a conserved
                     domain of approximately 30 amino acid residues found in a
                     number of proteins that transport or detoxify heavy
                     metals, for example, the CPx-type heavy metal ATPases and
                     copper chaperones. HMA domain...; Region: HMA; cd00371"
                     /db_xref="CDD:238219"
     misc_feature    complement(order(151829..151831,151838..151846))
                     /gene="ctpB"
                     /locus_tag="BCG_0136c"
                     /note="metal-binding site [ion binding]"
                     /db_xref="CDD:238219"
     misc_feature    complement(150608..151270)
                     /gene="ctpB"
                     /locus_tag="BCG_0136c"
                     /note="E1-E2 ATPase; Region: E1-E2_ATPase; pfam00122"
                     /db_xref="CDD:249606"
     misc_feature    complement(149882..>150121)
                     /gene="ctpB"
                     /locus_tag="BCG_0136c"
                     /note="Soluble P-type ATPase [General function prediction
                     only]; Region: COG4087"
                     /db_xref="CDD:226572"
     gene            152059..153573
                     /locus_tag="BCG_0137"
                     /db_xref="GeneID:4697687"
     CDS             152059..153573
                     /locus_tag="BCG_0137"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_976240.1"
                     /db_xref="GI:121636017"
                     /db_xref="GeneID:4697687"
                     /translation="MTPVTTFPLVDAILAGRDRNLDGVILIAAQHLLQTTHAMLRSLF
                     RVGLDPRNVAVIGKCYSTHPGVVDAMRADGIYVDDCSDAYAPHESFDTQYTRHVEWFF
                     AESWARLTAGRTARVVLLDDGGSLLAVAGAMLDASADVIGIEQTSAGYAKIVGCALGF
                     PVINIARSSAKLLYESPIIAARVTQTAFERTAGIDSSAAILITGAGAIGTALADVLRP
                     LHDRVDVYDTRSGCMTPIDLPNAIGGYDVIIGATGATSVPASMHELLRPGVLLMSASS
                     SDREFDAVALRRRTTPNPDCHADLRVADGSVDATLLNSGFPVNFDGSPMCGDASMALT
                     MALLAAAVLYASVAVADEMSSDHPHLGLIDQGDIVASFLNIDVPLQALSRLPLLSIDG
                     YRRLQVRSGHTLFRQGERADHFFVIESGELEALVDGKVILRLGAGDHFGEACLLGGMR
                     RIATVRACEPSVLWELDGKAFGDALHGDAAMREIAYGVARTRLMHAGASESLMV"
     misc_feature    <152410..152937
                     /locus_tag="BCG_0137"
                     /note="Short-chain dehydrogenases/reductases (SDR);
                     Region: SDR; cl21454"
                     /db_xref="CDD:271874"
     misc_feature    order(152668..152676,152680..152682,152734..152742,
                     152809..152814,152878..152880)
                     /locus_tag="BCG_0137"
                     /note="NAD binding site [chemical binding]; other site"
                     /db_xref="CDD:240631"
     misc_feature    153172..>153567
                     /locus_tag="BCG_0137"
                     /note="cAMP-binding proteins - catabolite gene activator
                     and regulatory subunit of cAMP-dependent protein kinases
                     [Signal transduction mechanisms]; Region: Crp; COG0664"
                     /db_xref="CDD:223736"
     misc_feature    153190..153504
                     /locus_tag="BCG_0137"
                     /note="effector domain of the CAP family of transcription
                     factors; members include CAP (or cAMP receptor protein
                     (CRP)), which binds cAMP, FNR (fumarate and nitrate
                     reduction), which uses an iron-sulfur cluster to sense
                     oxygen) and CooA, a heme containing CO...; Region: CAP_ED;
                     cd00038"
                     /db_xref="CDD:237999"
     misc_feature    order(153379..153384,153409..153417)
                     /locus_tag="BCG_0137"
                     /note="ligand binding site [chemical binding]; other site"
                     /db_xref="CDD:237999"
     misc_feature    order(153475..153483,153493..153501)
                     /locus_tag="BCG_0137"
                     /note="flexible hinge region; other site"
                     /db_xref="CDD:237999"
     gene            complement(153722..154006)
                     /gene="rpmB"
                     /locus_tag="BCG_0138c"
                     /db_xref="GeneID:4695457"
     CDS             complement(153722..154006)
                     /gene="rpmB"
                     /locus_tag="BCG_0138c"
                     /note="required for 70S ribosome assembly"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L28"
                     /protein_id="YP_976241.1"
                     /db_xref="GI:121636018"
                     /db_xref="GeneID:4695457"
                     /translation="MSARCQITGRTVGFGKAVSHSHRRTRRRWPPNIQLKAYYLPSED
                     RRIKVRVSAQGIKVIDRDGHRGRRRAARAGSAPAHFARQAGSSLRTAAIL"
     misc_feature    complement(<153830..154006)
                     /gene="rpmB"
                     /locus_tag="BCG_0138c"
                     /note="50S ribosomal protein L28; Reviewed; Region: rpmB;
                     PRK00359"
                     /db_xref="CDD:234736"
     gene            154116..155312
                     /locus_tag="BCG_0139"
                     /db_xref="GeneID:4697629"
     CDS             154116..155312
                     /locus_tag="BCG_0139"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_976242.1"
                     /db_xref="GI:121636019"
                     /db_xref="GeneID:4697629"
                     /translation="MRTPVILVAGQDHTDEVTGALLRRTGTVVVEHRFDGHVVRRMTA
                     TLSRGELITTEDALEFAHGCVSCTIRDDLLVLLRRLHRRDNVGRIVVHLAPWLEPQPI
                     CWAIDHVRVCVGHGYPDGPAALDVRVAAVVTCVDCVRWLPQSLGEDELPDGRTVAQVT
                     VGQAEFADLLVLTHPEPVAVAVLRRLAPRARITGGVDRVELALAHLDDNSRRGRTDTP
                     HTPLLAGLPPLAADGEVAIVEFSARRPFHPQRLHAAVDLLLDGVVRTRGRLWLANRPD
                     QVMWLESAGGGLRVASAGKWLAAMAASEVAYVDLERRLFADLMWVYPFGDRHTAMTVL
                     VCGADPTDIVNALNAALLSDDEMASPQRWQSYVDPFGDWHDDPCHEMPDAAGEFSAHR
                     NSGESR"
     misc_feature    154122..155171
                     /locus_tag="BCG_0139"
                     /note="Putative GTPases (G3E family) [General function
                     prediction only]; Region: COG0523"
                     /db_xref="CDD:223597"
     misc_feature    154827..155168
                     /locus_tag="BCG_0139"
                     /note="Cobalamin synthesis protein cobW C-terminal domain;
                     Region: CobW_C; smart00833"
                     /db_xref="CDD:214844"
     gene            complement(155407..160284)
                     /gene="ctpI"
                     /locus_tag="BCG_0140c"
                     /db_xref="GeneID:4696800"
     CDS             complement(155407..160284)
                     /gene="ctpI"
                     /locus_tag="BCG_0140c"
                     /EC_number="3.6.3.-"
                     /note="In Mycobacterium bovis BCG Pasteur, and
                     Mycobacterium bovis, a single base insertion (*-t) leads
                     to a product with a different COOH part compared to its
                     homolog in Mycobacterium tuberculosis strain H37Rv;
                     differs from Rv0107c by 3aa, V136A, P1247S, S1327A"
                     /codon_start=1
                     /transl_table=11
                     /product="cation-transporter atpase I ctpI"
                     /protein_id="YP_976243.1"
                     /db_xref="GI:121636020"
                     /db_xref="GeneID:4696800"
                     /translation="MKIPGVATVLGGVTNGVAQTVRAGARLPGSAAAAVQTLASPVLE
                     LTGPVVQSVVQTTGRAIGVRGSHNESPDGMTPPVRWRSGRRVHFDLDPLLPFPRWHEH
                     AAMVEEPVRRIPGVAEAHVEGSLGRLVVELEPDVDSDIAVDEVRDVVSAVAADIFLAG
                     SVSSPNSAPFADPGNPLAILVPLTAAAMDLVAMGATVTGWVARLPAAPQTTRALAALI
                     NHQPRMVSLMESRLGRVGTDIALAATTAAANGLTQSLGTPLLDLVQRSLQISEAAAHR
                     RVWRDREPALASPRRPQAPVVPIISSAGAKSQEPRHSWAAAAAGEASHVVVGGSIDAA
                     IDTAKGSRAGPVEQYVNQAANGSLIAAASALVAGGGTEDAAGAILAGVPRAAHMGRQA
                     FAAVLGRGLANTGQLVLDPGALRRLDRVRVVVIDGAALRGDNRAVLHAQGDEPGWDDD
                     RVYEVADALLHGEQAPEPDPDELPATGARLRWAPAQGPSATPAQGLEHADLVVDGQCV
                     GSVDVGWEVDPYAIPLLQTAHRTGARVVLRHVAGTEDLSASVGSTHPPGTPLLKLVRE
                     LRADRGPVLLITAVHRDFASTDTLAALAIADVGVALDDPRGATPWTADLITGTDLAAA
                     VRILSALPVARAASESAVHLAQGGTTLAGLLLVTGEQDKTTNPASFRRWLNPVNAAAA
                     TALVSGMWSAAKVLRMPDPTPQPLTAWHALDPEIVYSRLAGGSRPLAVEPGIPAWRRI
                     LDDLSYEPVMAPLRGPARTLAQLAVATRHELADPLTPILAVGAAASAIVGSNIDALLV
                     AGVMTVNAITGGVQRLRAEAAAAELFAEQDQLVRRVVVPAVATTRRRLEAARHATRTA
                     TVSAKSLRVGDVIDLAAPEVVPADARLLVAEDLEVDESFLTGESLPVDKQVDPVAVND
                     PDRASMLFEGSTIVAGHARAIVVATGVGTAAHRAISAVADVETAAGVQARLRELTSKV
                     LPMTLAGGAAVTALALLRRASLRQAVADGVAIAVAAVPEGLPLVATLSQLAAAQRLTA
                     RGALVRSPRTIEALGRVDTICFDKTGTLTENRLRVVCALPSSTAAERDPLPQTTDAPS
                     AEVLRAAARASTQPHNGEGHAHATDEAILAAASALAGSLSSQGDSEWVVLAEVPFESS
                     RGYAAAIGRVGTDGIPMLMLKGAPETILPRCRLADPGVDHEHAESVVRHLAEQGLRVL
                     AVAQRTWDNGTTHDDETDADAVDAVAHDLELIGYVGLADTARPSSRPLIEALLDAERN
                     VVLITGDHPITARAIARQLGLPADARVVTGAELAVLDEEAHAKLAADMQVFARVSPEQ
                     KVQIVASLQRCGRVTAMVGDGANDAAAIRMADVGIGVSGRGSSAARGAADIVLTDDDL
                     GVLLDALVEGRSMWAGVRDAVTILVGGNVGEVLFTVIGTAFGAGRAPVGTRQLLLVNL
                     LTDMFPALAVAVTSQFAEPDDAEYPTDDAAERAQREHRRAVLIGPTPSLDAPLLRQIV
                     NRGVVTAAGATAAWAIGRWTPGTERRTATMGLTALVMTQLAQTLLTRRHSPLVIATAL
                     GSAGVLVGIIQTPVISHFFGCTPLGPVAWTGVFSATAGATAVSALAPKWLASTVGVVQ
                     PDERPDDAEDSDAGG"
     misc_feature    complement(155443..158217)
                     /gene="ctpI"
                     /locus_tag="BCG_0140c"
                     /note="Cation transport ATPase [Inorganic ion transport
                     and metabolism]; Region: MgtA; COG0474"
                     /db_xref="CDD:223550"
     misc_feature    complement(157156..>157716)
                     /gene="ctpI"
                     /locus_tag="BCG_0140c"
                     /note="E1-E2 ATPase; Region: E1-E2_ATPase; pfam00122"
                     /db_xref="CDD:249606"
     misc_feature    complement(156754..>156891)
                     /gene="ctpI"
                     /locus_tag="BCG_0140c"
                     /note="Putative hydrolase of sodium-potassium ATPase alpha
                     subunit; Region: Hydrolase_like2; pfam13246"
                     /db_xref="CDD:257602"
     misc_feature    complement(156214..156546)
                     /gene="ctpI"
                     /locus_tag="BCG_0140c"
                     /note="Haloacid dehalogenase-like hydrolases. The haloacid
                     dehalogenase-like (HAD) superfamily includes L-2-haloacid
                     dehalogenase, epoxide hydrolase, phosphoserine
                     phosphatase, phosphomannomutase, phosphoglycolate
                     phosphatase, P-type ATPase, and many others; Region:
                     HAD_like; cd01427"
                     /db_xref="CDD:119389"
     misc_feature    complement(156484..156486)
                     /gene="ctpI"
                     /locus_tag="BCG_0140c"
                     /note="motif II; other site"
                     /db_xref="CDD:119389"
     misc_feature    complement(155479..155997)
                     /gene="ctpI"
                     /locus_tag="BCG_0140c"
                     /note="Cation transporting ATPase, C-terminus; Region:
                     Cation_ATPase_C; pfam00689"
                     /db_xref="CDD:250058"
     gene            complement(160638..160847)
                     /locus_tag="BCG_0141c"
                     /db_xref="GeneID:4697539"
     CDS             complement(160638..160847)
                     /locus_tag="BCG_0141c"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_976244.1"
                     /db_xref="GI:121636021"
                     /db_xref="GeneID:4697539"
                     /translation="MVPVETLHSGDPITDVNGGGQRYIVLESKTVGDSCVVLELESRV
                     NHQLQVIEKSFPAGYHVGRAHHRIL"
     gene            161126..162616
                     /gene="PE_PGRS1"
                     /locus_tag="BCG_0142"
                     /db_xref="GeneID:4698119"
     CDS             161126..162616
                     /gene="PE_PGRS1"
                     /locus_tag="BCG_0142"
                     /note="Differs from Rv0109 by 1aa, G346R"
                     /codon_start=1
                     /transl_table=11
                     /product="PE-PGRS family protein"
                     /protein_id="YP_976245.1"
                     /db_xref="GI:121636022"
                     /db_xref="GeneID:4698119"
                     /translation="MSLLITSPATVAAAATHLAGIGSALSTANAAAAAPTTALSVAGA
                     DEVSVLIAALFEAYAQEYQALSAQALAFHDQFVQALNMGAVCYAAAETANATPLQALQ
                     TVQQNVLTVVNAPTQALLGRPIIGNGANGLPNTGQDGGPGGLLFGNGGNGGSGGVDQA
                     GGNGGAAGLIGNGGSGGVGGPGIAGSAGGAGGAGGLLFGNGGPGGAGGIGTTGDGGPG
                     GAGGNAIGLFGSGGTGGMGGVGGMGGVGNGGNAGNGGTAGLFGHGGAGGAGGIGSADG
                     GLGGGGGNGRFMGNGGVGGAGGYGASGDGGNAGNGGLGGVFGDGGAGGTGGLGDVNGG
                     LAGIGGNAGFVGNGGAGGNGQLGSGAVSSAGGMGGNGGLVFGNGGPGGLGGPGTSAGN
                     GGMGGNAVGLFGQGGAGGAGGSGFGAGIPGGRGGDGGSGGLIGDGGTGGGAGAGDAAA
                     SAGGNGGNARLIGNGGDGGPGMFGGPGGAGGSGGTIFGFAGTPGPS"
     misc_feature    161126..161407
                     /gene="PE_PGRS1"
                     /locus_tag="BCG_0142"
                     /note="PE family; Region: PE; pfam00934"
                     /db_xref="CDD:250239"
     gene            162764..163513
                     /locus_tag="BCG_0143"
                     /db_xref="GeneID:4696296"
     CDS             162764..163513
                     /locus_tag="BCG_0143"
                     /codon_start=1
                     /transl_table=11
                     /product="integral membrane protein"
                     /protein_id="YP_976246.1"
                     /db_xref="GI:121636023"
                     /db_xref="GeneID:4696296"
                     /translation="MRVGPVGHQCAECVREGARAVRQPRTPFGGRQRSATPVVTYTLI
                     SLNALVFVMQVTVMGLERQLALWPPAVASGQTYRLVTSAFLHYGAMHLLLNMWALYVV
                     GPPLEMWLGRLRFGALYAVSALGGSVLVYLIAPLNTATAGASGAVFGLFGATFMVARR
                     LHLDVRWVVALIVINLAFTFLAPAISWQGHVGGLVTGALVAATYVYAPRERRNLIQAT
                     VTITVLVAFVVLIGWRTVDLLALFGGRLNLS"
     misc_feature    162971..163390
                     /locus_tag="BCG_0143"
                     /note="Rhomboid family; Region: Rhomboid; pfam01694"
                     /db_xref="CDD:250801"
     gene            163694..165751
                     /locus_tag="BCG_0144"
                     /db_xref="GeneID:4697514"
     CDS             163694..165751
                     /locus_tag="BCG_0144"
                     /EC_number="2.3.1.-"
                     /codon_start=1
                     /transl_table=11
                     /product="acyltransferase"
                     /protein_id="YP_976247.1"
                     /db_xref="GI:121636024"
                     /db_xref="GeneID:4697514"
                     /translation="MPARSVPRPRWVAPVRRVGRLAVWDRPERRSGIPALDGLRAIAV
                     ALVLASHGGIPGMGGGFIGVDAFFVLSGFLITSLLLDELGRTGRIDLSGFWIRRARRL
                     LPALVLMVLTVSAARALFPDQALTGLRSDAIAAFLWTANWRFVAQNTDYFTQGAPPSP
                     LQHTWSLGVEEQYYVVWPLLLIGATLLLAARARRRCRRATVGGVRFAAFLIASLGTMA
                     SATAAVAFTSAATRDRIYFGTDTRAQALLIGSAAAALLVRDWPSLNRGWCLIRTRWGR
                     RIARLLPFVGLAGLAVTTHVATGSVGEFRHGLLIVVAGAAVIVVASVAMEQRGAVARI
                     LAWRPLVWLGTISYGVYLWHWPIFLALNGQRTGWSGPALFAARCAATVVLAGASWWLI
                     EQPIRRWRPARVPLLPLAAATVASAAAVTMLVVPVGAGPGLREIGLPPGVSAVAAVSP
                     SPPEASQPAPGPRDPNRPFTVSVFGDSIGWTLMHYLPPTPGFRFIDHTVIGCSLVRGT
                     PYRYIGQTLEQRAECDGWPARWSAQVNRDQPDVALLIVGRWETVDRVNEGRWTHIGDP
                     TFDAYLNAELQRALSIVGSTGVRVMVTTVPYSRGGEKPDGRLYPEDQPERVNKWNAML
                     HNAISQHSNVGMIDLNKKLCPDGVYTAKVDGIKVRSDGVHLTQEGVKWLIPWLEDSVR
                     VAS"
     misc_feature    163781..164911
                     /locus_tag="BCG_0144"
                     /note="Predicted acyltransferases [Lipid metabolism];
                     Region: COG1835"
                     /db_xref="CDD:224748"
     misc_feature    165110..165700
                     /locus_tag="BCG_0144"
                     /note="GDSL-like Lipase/Acylhydrolase family; Region:
                     Lipase_GDSL_2; pfam13472"
                     /db_xref="CDD:257796"
     misc_feature    order(165359..165361,165674..165676,165683..165685)
                     /locus_tag="BCG_0144"
                     /note="active site"
                     /db_xref="CDD:238141"
     misc_feature    order(165674..165676,165683..165685)
                     /locus_tag="BCG_0144"
                     /note="catalytic triad [active]"
                     /db_xref="CDD:238141"
     gene            166033..166989
                     /gene="gca"
                     /locus_tag="BCG_0145"
                     /db_xref="GeneID:4696313"
     CDS             166033..166989
                     /gene="gca"
                     /locus_tag="BCG_0145"
                     /EC_number="4.2.1.47"
                     /codon_start=1
                     /transl_table=11
                     /product="GDP-mannose 4,6-dehydratase"
                     /protein_id="YP_976248.1"
                     /db_xref="GI:121636025"
                     /db_xref="GeneID:4696313"
                     /translation="MKVWITGAGGMMGSHLAEMLLAAGHDVYATYCRPTIDPSDLQFN
                     GAEVDITDWCSVYDSIATFRPDAVFHLAAQSYPAVSWARPVETLTTNMVGTAIVFEAL
                     RRVRPHAKIIVAGSSAEYGFVDPSEVPINERRELRPLHPYGVSKAATDMLAYQYHKSY
                     GMHTVVARIFNCTGPRKVGDALSDFVRRCTWLEHHPEQSAIRVGNLKTKRTIVDVRDL
                     NRALMLMLDKGEAGADYNVGGSIAYEMGDVLKQVIAACKRDDIVPEVDPALLRPTDEK
                     IIYGDCSKLAAITGWQQEICLTQTIADMFDYWRSKSESALMV"
     misc_feature    166033..166974
                     /gene="gca"
                     /locus_tag="BCG_0145"
                     /note="Nucleoside-diphosphate-sugar epimerases [Cell
                     envelope biogenesis, outer membrane / Carbohydrate
                     transport and metabolism]; Region: WcaG; COG0451"
                     /db_xref="CDD:223528"
     misc_feature    166036..166959
                     /gene="gca"
                     /locus_tag="BCG_0145"
                     /note="Short-chain dehydrogenases/reductases (SDR);
                     Region: SDR; cl21454"
                     /db_xref="CDD:271874"
     misc_feature    order(166051..166053,166057..166062,166066..166068,
                     166123..166131,166243..166251,166372..166380,
                     166456..166458,166468..166470,166537..166548)
                     /gene="gca"
                     /locus_tag="BCG_0145"
                     /note="NAD(P) binding site [chemical binding]; other site"
                     /db_xref="CDD:187535"
     misc_feature    order(166303..166305,166378..166380,166456..166458,
                     166468..166470)
                     /gene="gca"
                     /locus_tag="BCG_0145"
                     /note="active site"
                     /db_xref="CDD:187535"
     gene            167063..167653
                     /gene="gmhA"
                     /locus_tag="BCG_0146"
                     /db_xref="GeneID:4696528"
     CDS             167063..167653
                     /gene="gmhA"
                     /locus_tag="BCG_0146"
                     /EC_number="5.-.-.-"
                     /note="catalyzes the isomerization of sedoheptulose
                     7-phosphate to D-glycero-D-manno-heptose 7-phosphate"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoheptose isomerase"
                     /protein_id="YP_976249.1"
                     /db_xref="GI:121636026"
                     /db_xref="GeneID:4696528"
                     /translation="MCTARTAEEIFVETIAVKTRILNDRVLLEAARAIGDRLIAGYRA
                     GARVFMCGNGGSAADAQHFAAELTGHLIFDRPPLGAEALHANSSHLTAVANDYDYDTV
                     FARALEGSARPGDTLFAISTSGNSMSVLRAAKTARELGVTVVAMTGESGGQLAEFADF
                     LINVPSRDTGRIQESHIVFIHAISEHVEHALFAPRQ"
     misc_feature    167093..167629
                     /gene="gmhA"
                     /locus_tag="BCG_0146"
                     /note="Phosphoheptose isomerase is a member of the SIS
                     (Sugar ISomerase) superfamily. Phosphoheptose isomerase
                     catalyzes the isomerization of sedoheptulose 7-phosphate
                     into D-glycero-D-mannoheptose 7-phosphate. This is the
                     first step of the biosynthesis of...; Region: SIS_GmhA;
                     cd05006"
                     /db_xref="CDD:240139"
     misc_feature    order(167102..167104,167114..167116,167156..167158,
                     167165..167167,167225..167227,167243..167248,
                     167579..167584,167594..167596,167603..167605,
                     167615..167617,167627..167629)
                     /gene="gmhA"
                     /locus_tag="BCG_0146"
                     /note="dimer interface [polypeptide binding]; other site"
                     /db_xref="CDD:240139"
     misc_feature    order(167219..167227,167423..167431,167438..167440,
                     167567..167569,167579..167581)
                     /gene="gmhA"
                     /locus_tag="BCG_0146"
                     /note="active site"
                     /db_xref="CDD:240139"
     gene            167685..168257
                     /locus_tag="BCG_0147"
                     /db_xref="GeneID:4697849"
     CDS             167685..168257
                     /locus_tag="BCG_0147"
                     /EC_number="4.-.-.-"
                     /note="Differs from Rv0114 by 1aa, R121G"
                     /codon_start=1
                     /transl_table=11
                     /product="dehydratase"
                     /protein_id="YP_976250.1"
                     /db_xref="GI:121636027"
                     /db_xref="GeneID:4697849"
                     /translation="MVAERAGHQWCLFLDRDGVINRQVVGDYVRNWRQFEWLPGAARA
                     LKKLRAWAPYIVVVTNQQGVGAGLMSAVDVMVIHRHLQMQLASDGVLIDGFQVCPHHR
                     SQRCGCRKPRPGLVLDWLRRHPDSEPLLSIVVGDSLSDLELAHNVAAAAGACASVQIG
                     GASSGGVADASFDSLWEFAVAVGHARGERG"
     misc_feature    167697..168248
                     /locus_tag="BCG_0147"
                     /note="Histidinol phosphatase and related phosphatases
                     [Amino acid transport and metabolism]; Region: HisB;
                     COG0241"
                     /db_xref="CDD:223319"
     misc_feature    167715..168122
                     /locus_tag="BCG_0147"
                     /note="Haloacid dehalogenase-like hydrolases. The haloacid
                     dehalogenase-like (HAD) superfamily includes L-2-haloacid
                     dehalogenase, epoxide hydrolase, phosphoserine
                     phosphatase, phosphomannomutase, phosphoglycolate
                     phosphatase, P-type ATPase, and many others; Region:
                     HAD_like; cd01427"
                     /db_xref="CDD:119389"
     misc_feature    order(167727..167735,167859..167864)
                     /locus_tag="BCG_0147"
                     /note="active site"
                     /db_xref="CDD:119389"
     misc_feature    167727..167744
                     /locus_tag="BCG_0147"
                     /note="motif I; other site"
                     /db_xref="CDD:119389"
     misc_feature    167859..167861
                     /locus_tag="BCG_0147"
                     /note="motif II; other site"
                     /db_xref="CDD:119389"
     gene            168257..169324
                     /locus_tag="BCG_0149"
                     /db_xref="GeneID:4697418"
     CDS             168257..169324
                     /locus_tag="BCG_0149"
                     /EC_number="2.-.-.-"
                     /note="In Mycobacterium bovis BCG Pasteur, and
                     Mycobacterium bovis, a single base insertion (*-c)
                     equivalent to Mycobacterium tuberculosis H37Rv position
                     139559, leads to shorter product with a different COOH
                     part compared to its homolog in Mycobacterium tuberculosis
                     strain H37Rv. In addition, in Mycobacterium bovis, a
                     single base insertion, at position equivalent to 138823,
                     leads to a different NH2 part"
                     /codon_start=1
                     /transl_table=11
                     /product="sugar kinase"
                     /protein_id="YP_976251.1"
                     /db_xref="GI:121636028"
                     /db_xref="GeneID:4697418"
                     /translation="MAILRGRAPLRLGLGGGGTDVEPYSSQFGGRILSVTIDKYAYAF
                     AERGTGDEIAFRSPDRDRAGQASIDDLASLEEDFPLHVAVYRRVIAEFNGGTPFPLQL
                     ATQVDAPPGSGLGSSSALVVAMLLTTCALIGSSPGPYELARLAWEIERVDLGMAGGWQ
                     DHYAAAFGGFNFMESRPNGEVVVNPLRIRREVIAELEASLLLYFGGVSRLSSEVIADQ
                     QRNVVERDADALAATHSICAEALEMKDLLVVGDIPGFADSLLRGWQAKKRTSTRISNP
                     AIEHAYQVAQSSGMVAGKVSGAGGGGFLMMIVDPRRRIEVARSLERECGGSVAPCLFT
                     KGGAVTWHIPESTAPRKAWSC"
     misc_feature    168257..169288
                     /locus_tag="BCG_0149"
                     /note="Predicted kinase related to galactokinase and
                     mevalonate kinase [General function prediction only];
                     Region: COG2605"
                     /db_xref="CDD:225325"
     misc_feature    168575..168763
                     /locus_tag="BCG_0149"
                     /note="GHMP kinases N terminal domain; Region:
                     GHMP_kinases_N; pfam00288"
                     /db_xref="CDD:249743"
     gene            complement(170012..170767)
                     /locus_tag="BCG_0150c"
                     /db_xref="GeneID:4695709"
     CDS             complement(170012..170767)
                     /locus_tag="BCG_0150c"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_976252.1"
                     /db_xref="GI:121636029"
                     /db_xref="GeneID:4695709"
                     /translation="MRRVVRYLSVVVAITLMLTAESVSIATAAVPPLQPIPGVASVSP
                     ANGAVVGVAHPVVVTFTTPVTDRRAVERSIRISTPHNTTGHFEWVASNVVRWVPHRYW
                     PPHTRVSVGVQELTEGFETGDALIGVASISAHTFTVSRNGEVLRTMPASLGKPSRPTP
                     IGSFHAMSKERTVVMDSRTIGIPLNSSDGYLLTAHYAVRVTWSGVYVHSAPWSVNSQG
                     YANVSHGCINLSPDNAAWYFDAVTVGDPIEVVG"
     misc_feature    complement(170015..170725)
                     /locus_tag="BCG_0150c"
                     /note="Uncharacterized protein conserved in bacteria
                     [Function unknown]; Region: ErfK; COG1376"
                     /db_xref="CDD:224294"
     misc_feature    complement(170396..170680)
                     /locus_tag="BCG_0150c"
                     /note="IgD-like repeat domain of mycobacterial
                     L,D-transpeptidases; Region: LDT_IgD_like; cl17506"
                     /db_xref="CDD:248060"
     misc_feature    complement(170021..170386)
                     /locus_tag="BCG_0150c"
                     /note="L,D-transpeptidase catalytic domain; Region: YkuD;
                     pfam03734"
                     /db_xref="CDD:252135"
     gene            170945..171889
                     /gene="oxyS"
                     /locus_tag="BCG_0151"
                     /db_xref="GeneID:4697654"
     CDS             170945..171889
                     /gene="oxyS"
                     /locus_tag="BCG_0151"
                     /codon_start=1
                     /transl_table=11
                     /product="oxidative stress response regulatory protein
                     oxyS"
                     /protein_id="YP_976253.1"
                     /db_xref="GI:121636030"
                     /db_xref="GeneID:4697654"
                     /translation="MLFRQLEYFVAVAQERHFARAAEKCYVSQPALSSAIAKLERELN
                     VTLINRGHSFEGLTREGERLVVWAKRILAEHAAFKAEVDAVRSGITGTLRLGTVPTAS
                     TTASLVLSAFCSAHPLAKVQVCSRLAATELYRRLREFELDAVIVHPETQDSDDVDLVP
                     LYEEQYVLLSPADMLPPGTSTLVWRDAAQLPLALLTADMRDRQVIDAAFADHAVSAIP
                     QVETDSVASLFAQVATGNWASIVPHTWLWAMPMSGPTGGEIRAVELVDPVLKAQIALA
                     TNALGPGSPVARALITCAQALALNEFFDTQLRGITRRR"
     misc_feature    170945..171838
                     /gene="oxyS"
                     /locus_tag="BCG_0151"
                     /note="Transcriptional regulator [Transcription]; Region:
                     LysR; COG0583"
                     /db_xref="CDD:223656"
     misc_feature    170951..171130
                     /gene="oxyS"
                     /locus_tag="BCG_0151"
                     /note="Bacterial regulatory helix-turn-helix protein, lysR
                     family; Region: HTH_1; pfam00126"
                     /db_xref="CDD:249610"
     misc_feature    171218..171826
                     /gene="oxyS"
                     /locus_tag="BCG_0151"
                     /note="The substrate binding domain of LysR-type
                     transcriptional regulators (LTTRs), a member of the type 2
                     periplasmic binding fold protein superfamily; Region:
                     PBP2_LTTR_substrate; cd05466"
                     /db_xref="CDD:176102"
     misc_feature    order(171260..171265,171269..171274,171281..171283,
                     171293..171295,171299..171313,171317..171322,
                     171599..171616,171632..171637,171641..171646)
                     /gene="oxyS"
                     /locus_tag="BCG_0151"
                     /note="dimerization interface [polypeptide binding]; other
                     site"
                     /db_xref="CDD:176102"
     gene            complement(171873..173621)
                     /gene="oxcA"
                     /locus_tag="BCG_0152c"
                     /db_xref="GeneID:4695405"
     CDS             complement(171873..173621)
                     /gene="oxcA"
                     /locus_tag="BCG_0152c"
                     /EC_number="4.1.1.8"
                     /note="catalyzes the formation of formyl-CoA from
                     oxalyl-CoA"
                     /codon_start=1
                     /transl_table=11
                     /product="oxalyl-CoA decarboxylase"
                     /protein_id="YP_976254.1"
                     /db_xref="GI:121636031"
                     /db_xref="GeneID:4695405"
                     /translation="MTTRSASPCTVLTDGCHLVVDALKANDVDTIYGVVGIPITDLAR
                     AAQASGIRYIGFRHEASAGNAAAAAGFLTARPGVCLTTSGPGFLNGLPALANATTNCF
                     PMIQISGSSSRPMVDLQRGDYQDLDQLNAARPFVKAAYRIGQVQDIGRGVARAIRTAT
                     SGRPGGVYLDIPGDVLGQAVEASAASGAIWRPVDPAPRLLPAPEAIDRALDVLAQAQR
                     PLLVLGKGAAYAQADNVIREFVEHTGIPFLPMSMAKGLLPDSHPQSAAAARSLAMARA
                     DVVLLVGARLNWLLGNGESPQWSADAKFIQVDIEASEFDSNRPIVAPLTGDIGSVMSA
                     LLEAAADRSSVASAAWTGELADRKARNSAKMRRRLADDHHPMRFYNALGAIRSVLQRN
                     PDVYVVNEGANALDLARNIIDMHLPRHRLDSGTWGVMGIGMGYAIAAAVETGRPVVAI
                     EGDSAFGFSGMEFETICRYRLPVTVVILNNGGVYRGDEATIFRSAAPVWRHDPAPTVL
                     NAHARHELIAEAFGGKGYHVSTPTELESALTDALASNGPSLIDCELDPADGVESGHLA
                     KLNTTSAATPAISGDG"
     misc_feature    complement(171891..173588)
                     /gene="oxcA"
                     /locus_tag="BCG_0152c"
                     /note="putative oxalyl-CoA decarboxylase; Validated;
                     Region: PRK09259"
                     /db_xref="CDD:236433"
     misc_feature    complement(173106..173573)
                     /gene="oxcA"
                     /locus_tag="BCG_0152c"
                     /note="Pyrimidine (PYR) binding domain of POX and related
                     proteins; Region: TPP_PYR_POX_like; cd07035"
                     /db_xref="CDD:132918"
     misc_feature    complement(order(173322..173327,173334..173336,
                     173346..173348,173367..173369,173403..173411,
                     173415..173420,173427..173432,173439..173441,
                     173448..173468,173490..173492,173502..173504,
                     173514..173519,173532..173534))
                     /gene="oxcA"
                     /locus_tag="BCG_0152c"
                     /note="PYR/PP interface [polypeptide binding]; other site"
                     /db_xref="CDD:132918"
     misc_feature    complement(order(173220..173222,173229..173231,
                     173337..173339,173346..173351,173355..173360,
                     173367..173369,173442..173444,173448..173459,
                     173463..173465,173490..173492,173502..173504,
                     173511..173519))
                     /gene="oxcA"
                     /locus_tag="BCG_0152c"
                     /note="dimer interface [polypeptide binding]; other site"
                     /db_xref="CDD:132918"
     misc_feature    complement(order(173355..173357,173367..173369,
                     173445..173447,173517..173519))
                     /gene="oxcA"
                     /locus_tag="BCG_0152c"
                     /note="TPP binding site [chemical binding]; other site"
                     /db_xref="CDD:132918"
     misc_feature    complement(172617..173006)
                     /gene="oxcA"
                     /locus_tag="BCG_0152c"
                     /note="Thiamine pyrophosphate enzyme, central domain;
                     Region: TPP_enzyme_M; pfam00205"
                     /db_xref="CDD:249676"
     misc_feature    complement(171957..172490)
                     /gene="oxcA"
                     /locus_tag="BCG_0152c"
                     /note="Thiamine pyrophosphate (TPP) family, BZL_OCoD_HPCL
                     subfamily, TPP-binding module; composed of proteins
                     similar to benzaldehyde lyase (BZL), oxalyl-CoA
                     decarboxylase (OCoD) and 2-hydroxyphytanoyl-CoA lyase
                     (2-HPCL). Pseudomonas fluorescens biovar I BZL...; Region:
                     TPP_BZL_OCoD_HPCL; cd02004"
                     /db_xref="CDD:238962"
     misc_feature    complement(order(172170..172172,172176..172178,
                     172182..172184,172257..172268,172335..172337,
                     172341..172343,172410..172421,172488..172490))
                     /gene="oxcA"
                     /locus_tag="BCG_0152c"
                     /note="TPP-binding site; other site"
                     /db_xref="CDD:238962"
     misc_feature    complement(order(172059..172064,172074..172076,
                     172080..172085,172092..172094,172104..172106,
                     172110..172112,172143..172145,172230..172232,
                     172239..172241,172248..172253,172263..172265,
                     172344..172346))
                     /gene="oxcA"
                     /locus_tag="BCG_0152c"
                     /note="dimer interface [polypeptide binding]; other site"
                     /db_xref="CDD:238962"
     gene            173794..175371
                     /gene="fadD7"
                     /locus_tag="BCG_0153"
                     /db_xref="GeneID:4695404"
     CDS             173794..175371
                     /gene="fadD7"
                     /locus_tag="BCG_0153"
                     /EC_number="2.3.1.86"
                     /note="activates fatty acids by binding to coenzyme A"
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-CoA synthetase"
                     /protein_id="YP_976255.1"
                     /db_xref="GI:121636032"
                     /db_xref="GeneID:4695404"
                     /translation="MASDFGPRIADLVEVAATRLPEAPALVVTADRIAISHRDLARLV
                     DELAGQLTRSGLLPGDRVALRMGSNAEFVVALLAASRADLVVVPLDPALPITEQRVRS
                     QAAGARVVLIDADGPHDRAEPTTRWWPLTVNVGGDSGPSGGTLSVHLDAATEPNPATS
                     TPEGLRPDDAMIMFTGGTTGLPKMVPWTHANIASSVRAIITGYRLSPRDATVAVMPLY
                     HGHGLIASLLATLASGGAVSLPARGRFSAHTFWDDIKAVGATWYTAVPTIHQILLERS
                     ATEPSGRKPAALRFIRSCSAPLTAQAALALQTEFAAPVVCAFGMTEATHQVTTTQIEG
                     IDQTETPVVSTGLVGRSTGAQIRIVGSDGLPLPAGAVGEIWLRGTTVVRGYLGDPTIT
                     AANFTDGWLRTGDLGSLSAAGDLSIRGRIKELINRGGEKISPERVEGVLASHPNVMEA
                     AVFGVPHQLYGEAVAAVIVPRESAPPTREELVQFCRERLAAFEIPASFQEASGLPHTA
                     KGSLDRRAVAERFGHSV"
     misc_feature    173794..175368
                     /gene="fadD7"
                     /locus_tag="BCG_0153"
                     /note="acyl-CoA synthetase; Validated; Region: PRK05852"
                     /db_xref="CDD:235625"
     misc_feature    173923..>174573
                     /gene="fadD7"
                     /locus_tag="BCG_0153"
                     /note="Adenylate forming domain, Class I; Region:
                     AFD_class_I; cl17068"
                     /db_xref="CDD:266508"
     misc_feature    174289..175350
                     /gene="fadD7"
                     /locus_tag="BCG_0153"
                     /note="Subfamily of fatty acid CoA ligase (FACL) similar
                     to Fum10p of Gibberella moniliformis; Region:
                     FACL_fum10p_like; cd05926"
                     /db_xref="CDD:213292"
     misc_feature    order(174307..174309,174316..174333,174337..174342)
                     /gene="fadD7"
                     /locus_tag="BCG_0153"
                     /note="acyl-activating enzyme (AAE) consensus motif; other
                     site"
                     /db_xref="CDD:213292"
     misc_feature    order(174307..174309,174316..174333,174337..174342)
                     /gene="fadD7"
                     /locus_tag="BCG_0153"
                     /note="acyl-activating enzyme (AAE) consensus motif; other
                     site"
                     /db_xref="CDD:213270"
     misc_feature    order(174316..174318,174673..174678,174739..174756,
                     175006..175008,175042..175044,175051..175053,
                     175084..175086,175324..175326)
                     /gene="fadD7"
                     /locus_tag="BCG_0153"
                     /note="putative AMP binding site [chemical binding]; other
                     site"
                     /db_xref="CDD:213292"
     misc_feature    order(174316..174318,174436..174441,174586..174588,
                     174592..174597,174604..174606,174673..174678,
                     174739..174756,175006..175008,175042..175044,
                     175051..175053,175075..175086,175267..175269)
                     /gene="fadD7"
                     /locus_tag="BCG_0153"
                     /note="putative active site [active]"
                     /db_xref="CDD:213292"
     misc_feature    order(174436..174438,174592..174597,174604..174606,
                     174673..174675,175075..175083,175249..175251,
                     175267..175269)
                     /gene="fadD7"
                     /locus_tag="BCG_0153"
                     /note="putative CoA binding site [chemical binding]; other
                     site"
                     /db_xref="CDD:213292"
     gene            complement(175372..177516)
                     /gene="fusA2b"
                     /locus_tag="BCG_0154c"
                     /gene_synonym="fusA"
                     /db_xref="GeneID:4696274"
     CDS             complement(175372..177516)
                     /gene="fusA2b"
                     /locus_tag="BCG_0154c"
                     /gene_synonym="fusA"
                     /standard_name="fus2"
                     /note="EF-G; promotes GTP-dependent translocation of the
                     ribosome during translation; many organisms have multiple
                     copies of this gene"
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor G"
                     /protein_id="YP_976256.1"
                     /db_xref="GI:121636033"
                     /db_xref="GeneID:4696274"
                     /translation="MADRVNASQGAAAAPTANGPGGVRNVVLVGPSGGGKTTLIEALL
                     VAAKVLSRPGSVTEGTTVCDFDEAEIRQQRSVGLAVASLAYDGIKVNLVDTPGYADFV
                     GELWAGLRAADCALFVIAANEGVDEPTKSLWQECSQVGMPRAVVITKLDHARANYREA
                     LTAAQDAFGDKVLPLYLPSGDGLIGLLSQALYEYADGKRTTRTPAESDTERIEEARGA
                     LIEGIIEESEDESLMERYLGGETIDESVLIQDLEKAVARGSFFPVIPVCSSTGVGTLE
                     LLEVATRGFPSPMEHPLPEVFTPQGVPHAELACDNDAPLLAEVVKTTSDPYVGRVSLV
                     RVFSGTIRPDTTVHVSGHFSSFFGGGTSNTHPDHDEDERIGVLSFPLGKQQRPAAAVV
                     AGDICAIGKLSRAETGDTLSDKAEPLVLKPWTMPEPLLPIAIAAHAKTDEDKLSVGLG
                     RLAAEDPTLRIEQNQETHQVVLWCMGEAHAGVVLDTLANRYGVSVDTIELRVPLRETF
                     AGNAKGHGRHIKQSGGHGQYGVCDIEVEPLPEGSGFEFLDKVVGGAVPRQFIPSVEKG
                     VRAQMDKGVHAGYPVVDIRVTLLDGKAHSVDSSDFAFQMAGALALREAAAATKVILLE
                     PIDEISVLVPDDFVGAVLGDLSSRRGRVLGTETAGHDRTVIKAEVPQVELTRYAIDLR
                     SLAHGAASFTRSFARYEPMPESAAARVKAGAG"
     misc_feature    complement(176653..177444)
                     /gene="fusA2b"
                     /locus_tag="BCG_0154c"
                     /gene_synonym="fusA"
                     /note="Rat sarcoma (Ras)-like superfamily of small
                     guanosine triphosphatases (GTPases); Region:
                     Ras_like_GTPase; cl17170"
                     /db_xref="CDD:266525"
     misc_feature    complement(175384..177432)
                     /gene="fusA2b"
                     /locus_tag="BCG_0154c"
                     /gene_synonym="fusA"
                     /note="elongation factor G; Reviewed; Region: PRK12740"
                     /db_xref="CDD:237186"
     misc_feature    complement(177406..177429)
                     /gene="fusA2b"
                     /locus_tag="BCG_0154c"
                     /gene_synonym="fusA"
                     /note="G1 box; other site"
                     /db_xref="CDD:206648"
     misc_feature    complement(order(176710..176718,177064..177066,
                     177070..177075,177226..177228,177403..177423))
                     /gene="fusA2b"
                     /locus_tag="BCG_0154c"
                     /gene_synonym="fusA"
                     /note="GTP/Mg2+ binding site [chemical binding]; other
                     site"
                     /db_xref="CDD:206648"
     misc_feature    complement(177295..177297)
                     /gene="fusA2b"
                     /locus_tag="BCG_0154c"
                     /gene_synonym="fusA"
                     /note="G2 box; other site"
                     /db_xref="CDD:206648"
     misc_feature    complement(177274..177282)
                     /gene="fusA2b"
                     /locus_tag="BCG_0154c"
                     /gene_synonym="fusA"
                     /note="Switch I region; other site"
                     /db_xref="CDD:206648"
     misc_feature    complement(177226..177237)
                     /gene="fusA2b"
                     /locus_tag="BCG_0154c"
                     /gene_synonym="fusA"
                     /note="G3 box; other site"
                     /db_xref="CDD:206648"
     misc_feature    complement(order(177175..177180,177226..177231))
                     /gene="fusA2b"
                     /locus_tag="BCG_0154c"
                     /gene_synonym="fusA"
                     /note="Switch II region; other site"
                     /db_xref="CDD:206648"
     misc_feature    complement(177064..177075)
                     /gene="fusA2b"
                     /locus_tag="BCG_0154c"
                     /gene_synonym="fusA"
                     /note="G4 box; other site"
                     /db_xref="CDD:206648"
     misc_feature    complement(176710..176718)
                     /gene="fusA2b"
                     /locus_tag="BCG_0154c"
                     /gene_synonym="fusA"
                     /note="G5 box; other site"
                     /db_xref="CDD:206648"
     misc_feature    complement(176278..176574)
                     /gene="fusA2b"
                     /locus_tag="BCG_0154c"
                     /gene_synonym="fusA"
                     /note="EFG_mtEFG_II: this subfamily represents the domain
                     II of elongation factor G (EF-G) in bacteria and, the
                     C-terminus of mitochondrial Elongation factor G1 (mtEFG1)
                     and G2 (mtEFG2)_like proteins found in eukaryotes. During
                     the process of peptide synthesis...; Region: EFG_mtEFG_II;
                     cd04088"
                     /db_xref="CDD:239755"
     misc_feature    complement(176026..176244)
                     /gene="fusA2b"
                     /locus_tag="BCG_0154c"
                     /gene_synonym="fusA"
                     /note="Elongation Factor G, domain II; Region: EFG_II;
                     pfam14492"
                     /db_xref="CDD:258632"
     misc_feature    complement(175702..176004)
                     /gene="fusA2b"
                     /locus_tag="BCG_0154c"
                     /gene_synonym="fusA"
                     /note="EFG_mtEFG1_IV: domains similar to domain IV of the
                     bacterial translational elongation factor (EF) EF-G.
                     Included in this group is a domain of mitochondrial
                     Elongation factor G1 (mtEFG1) proteins homologous to
                     domain IV of EF-G. Eukaryotic cells harbor 2...; Region:
                     EFG_mtEFG1_IV; cd01434"
                     /db_xref="CDD:238715"
     misc_feature    complement(175411..175647)
                     /gene="fusA2b"
                     /locus_tag="BCG_0154c"
                     /gene_synonym="fusA"
                     /note="EFG_mtEFG_C: domains similar to the C-terminal
                     domain of the bacterial translational elongation factor
                     (EF) EF-G.  Included in this group is the C-terminus of
                     mitochondrial Elongation factor G1 (mtEFG1) and G2
                     (mtEFG2) proteins. Eukaryotic cells harbor 2...; Region:
                     EFG_mtEFG_C; cd03713"
                     /db_xref="CDD:239683"
     gene            complement(177652..178086)
                     /locus_tag="BCG_0155c"
                     /db_xref="GeneID:4695507"
     CDS             complement(177652..178086)
                     /locus_tag="BCG_0155c"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_976257.1"
                     /db_xref="GI:121636034"
                     /db_xref="GeneID:4695507"
                     /translation="MGEFDPKLRFAQSPVARLATSTPDGTPHLVPVVFALGARRPAEA
                     TGADVIYTAVDAKRKTTQRLRRLANLEHNPRASVLVDSYADDWTQLWWVRADGVAAIH
                     RDGEVMRAAYRLLRAKYAQYQSVPLNGPVIAIAVQRWASWHA"
     misc_feature    complement(177658..178083)
                     /locus_tag="BCG_0155c"
                     /note="PPOX class probable F420-dependent enzyme, Rv0121
                     family; Region: Rv0121_F420; TIGR03668"
                     /db_xref="CDD:132707"
     gene            178235..178603
                     /locus_tag="BCG_0156"
                     /db_xref="GeneID:4696264"
     CDS             178235..178603
                     /locus_tag="BCG_0156"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_976258.1"
                     /db_xref="GI:121636035"
                     /db_xref="GeneID:4696264"
                     /translation="MAGSVSAAAGIGWVGLNVTETNRDQCYRVERTTVDALTHPEYRV
                     HTRGVQRVRVTRNARKHRVSKHRIVAAMRHCGVPVIQEDGSLYYQGRDTSGRLTEVVA
                     VEADDGDLIITHAMPKEWKR"
     gene            178600..178968
                     /locus_tag="BCG_0157"
                     /db_xref="GeneID:4695590"
     CDS             178600..178968
                     /locus_tag="BCG_0157"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_976259.1"
                     /db_xref="GI:121636036"
                     /db_xref="GeneID:4695590"
                     /translation="MTKKPRNPADYVIGDDVEVSDVDLKQEEVYVDGERLTDERVEQM
                     ASESLRLAREREANLIPGGKSLSGGSAHSPAVQVVVSKATHAKLKELARSRKMSVSKL
                     LRPVLDEFVQRETGRILPRR"
     gene            179277..180893
                     /gene="PE_PGRS2"
                     /locus_tag="BCG_0158"
                     /db_xref="GeneID:4695953"
     CDS             179277..180893
                     /gene="PE_PGRS2"
                     /locus_tag="BCG_0158"
                     /note="In Mycobacterium bovis and Mycobacterium bovis BCG
                     Pasteur, a 180 bp insertion leads to a longer product in
                     the 3' direction compared to its homolog in Mycobacterium
                     tuberculosis strain H37Rv (538 aa versus 487 aa)"
                     /codon_start=1
                     /transl_table=11
                     /product="PE-PGRS family protein"
                     /protein_id="YP_976260.1"
                     /db_xref="GI:121636037"
                     /db_xref="GeneID:4695953"
                     /translation="MSFVSVAPEIVVAAATDLAGIGSAISAANAAAAAPTTAVLAAGA
                     DEVSAAIAALFSGHAQAYQALSAQAAAFHQQFVQTLAGGAGAYAAAEAQVEQQLLAAI
                     NAPTQALLGRPLIGNGADGAPGTGQAGGAGGILYGNGGNGGSGAAGQAGGAGGPAGLI
                     GHGGSGGAGGHGGWLWGNGGVGGSGGAGVGAGVAGGHGGAGGAAGLWGAGGGGGNGGN
                     GADANIVSGGDGGLGGAGGGGGWLYGDGGAGGHGGQGAIGLGGGAGGDGGQGGAGRGL
                     WGTGGAGGHGGQGGGTGGPPLPGQAGMGAAGGAGGLIGNGGAGGDGGVGASGGVAGVG
                     GAGGNAMLIGHGGAGGAGGDSSFANGAAGGAGGAGGHLFGNGGSGGHGGAVTAGNTGI
                     GGAGGVGGDARLIGHGGAGGAGGDRAGALVGRDGGPGGNGGAGGQLYGNGGDGGPGGQ
                     GGQAFGANNIGGTGGAGGNGGPAILSGNGGNGGAGGAGGAGGAGGGAGGVGGAGGAPG
                     TGGTLQAAVSGLVTALFGAPGQPGDTGQPG"
     misc_feature    179277..179516
                     /gene="PE_PGRS2"
                     /locus_tag="BCG_0158"
                     /note="PE family; Region: PE; pfam00934"
                     /db_xref="CDD:250239"
     gene            181045..182112
                     /gene="pepA"
                     /locus_tag="BCG_0159"
                     /db_xref="GeneID:4697722"
     CDS             181045..182112
                     /gene="pepA"
                     /locus_tag="BCG_0159"
                     /EC_number="3.4.21.-"
                     /codon_start=1
                     /transl_table=11
                     /product="serine protease pepA"
                     /protein_id="YP_976261.1"
                     /db_xref="GI:121636038"
                     /db_xref="GeneID:4697722"
                     /translation="MSNSRRRSLRWSWLLSVLAAVGLGLATAPAQAAPPALSQDRFAD
                     FPALPLDPSAMVAQVGPQVVNINTKLGYNNAVGAGTGIVIDPNGVVLTNNHVIAGATD
                     INAFSVGSGQTYGVDVVGYDRTQDVAVLQLRGAGGLPSAAIGGGVAVGEPVVAMGNSG
                     GQGGTPRAVPGRVVALGQTVQASDSLTGAEETLNGLIQFDAAIQPGDSGGPVVNGLGQ
                     VVGMNTAASDNFQLSQGGQGFAIPIGQAMAIAGQIRSGGGSPTVHIGPTAFLGLGVVD
                     NNGNGARVQRVVGSAPAASLGISTGDVITAVDGAPINSATAMADALNGHHPGDVISVT
                     WQTKSGGTRTGNVTLAEGPPA"
     misc_feature    181075..182109
                     /gene="pepA"
                     /locus_tag="BCG_0159"
                     /note="Trypsin-like serine proteases, typically
                     periplasmic, contain C-terminal PDZ domain
                     [Posttranslational modification, protein turnover,
                     chaperones]; Region: DegQ; COG0265"
                     /db_xref="CDD:223343"
     misc_feature    181279..181710
                     /gene="pepA"
                     /locus_tag="BCG_0159"
                     /note="Trypsin-like peptidase domain; Region: Trypsin_2;
                     pfam13365"
                     /db_xref="CDD:257693"
     misc_feature    181846..182046
                     /gene="pepA"
                     /locus_tag="BCG_0159"
                     /note="PDZ domain of trypsin-like serine proteases, such
                     as DegP/HtrA, which are oligomeric proteins involved in
                     heat-shock response, chaperone function, and apoptosis.
                     May be responsible for substrate recognition and/or
                     binding, as most PDZ domains bind...; Region:
                     PDZ_serine_protease; cd00987"
                     /db_xref="CDD:238487"
     misc_feature    order(181849..181860,181864..181866,181984..181989,
                     181996..182001)
                     /gene="pepA"
                     /locus_tag="BCG_0159"
                     /note="protein binding site [polypeptide binding]; other
                     site"
                     /db_xref="CDD:238487"
     gene            182221..184026
                     /gene="treS"
                     /locus_tag="BCG_0160"
                     /db_xref="GeneID:4696118"
     CDS             182221..184026
                     /gene="treS"
                     /locus_tag="BCG_0160"
                     /EC_number="5.4.99.-"
                     /codon_start=1
                     /transl_table=11
                     /product="trehalose synthase treS"
                     /protein_id="YP_976262.1"
                     /db_xref="GI:121636039"
                     /db_xref="GeneID:4696118"
                     /translation="MNEAEHSVEHPPVQGSHVEGGVVEHPDAKDFGSAAALPADPTWF
                     KHAVFYEVLVRAFFDASADGSGDLRGLIDRLDYLQWLGIDCIWLPPFYDSPLRDGGYD
                     IRDFYKVLPEFGTVDDFVALVDAAHRRGIRIITDLVMNHTSESHPWFQESRRDPDGPY
                     GDYYVWSDTSERYTDARIIFVDTEESNWSFDPVRRQFYWHRFFSHQPDLNYDNPAVQE
                     AMIDVIRFWLGLGIDGFRLDAVPYLFEREGTNCENLPETHAFLKRVRKVVDDEFPGRV
                     LLAEANQWPGDVVEYFGDPNTGGDECHMAFHFPLMPRIFMAVRRESRFPISEIIAQTP
                     PIPDMAQWGIFLRNHDELTLEMVTDEERDYMYAEYAKDPRMKANVGIRRRLAPLLDND
                     RNQIELFTALLLSLPGSPVLYYGDEIGMGDVIWLGDRDGVRIPMQWTPDRNAGFSTAN
                     PGRLYLPPSQDPVYGYQAVNVEAQRDTSTSLLNFTRTMLAVRRRHPAFAVGAFQELGG
                     SNPSVLAYVRQVAGDDGDTVLCVNNLSRFPQPIELDLQQWTNYTPVELTGHVEFPRIG
                     QVPYLLTLPGHGFYWFQLTTHEVGAPPTCGGERRL"
     misc_feature    182347..183972
                     /gene="treS"
                     /locus_tag="BCG_0160"
                     /note="trehalose synthase; Region: treS_nterm; TIGR02456"
                     /db_xref="CDD:233874"
     misc_feature    182347..183696
                     /gene="treS"
                     /locus_tag="BCG_0160"
                     /note="Alpha amylase catalytic domain found in Trehalose
                     synthetase; Region: AmyAc_TreS; cd11334"
                     /db_xref="CDD:200473"
     misc_feature    order(182926..182928,182932..182937,183058..183060,
                     183265..183270)
                     /gene="treS"
                     /locus_tag="BCG_0160"
                     /note="active site"
                     /db_xref="CDD:200473"
     misc_feature    order(182932..182934,183058..183060,183268..183270)
                     /gene="treS"
                     /locus_tag="BCG_0160"
                     /note="catalytic site [active]"
                     /db_xref="CDD:200473"
     gene            184129..185496
                     /locus_tag="BCG_0161"
                     /db_xref="GeneID:4696821"
     CDS             184129..185496
                     /locus_tag="BCG_0161"
                     /note="Differs from Rv0127 by 1aa, P18S"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_976263.1"
                     /db_xref="GI:121636040"
                     /db_xref="GeneID:4696821"
                     /translation="MTRSDTLATKLPWSDWLPRQRWYAGRNRELATVKPGVVVALRHN
                     LDLVLVDVTYTDGATERYQVLVGWDFEPASEYGTKAAIGVADDRTGFDALYDVAGPQF
                     LLSLIVSSAVCGTSTGEVTFTREPDVELPFAAQPRVCDAEQSNTSVIFDRRAILKVFR
                     RVSSGINPDIELNRVLTRAGNPHVARLLGAYQFGRPNRSPTDALAYALGMVTEYEANA
                     AEGWAMATASVRDLFAEGDLYAHEVGGDFAGESYRLGEAVASVHATLADSLGTAQATF
                     PVDRMLARLSSTVAVVPELREYAPTIEQQFQKLAAEAITVQRVHGDLHLGQVLRTPES
                     WLLIDFEGEPGQPLDERRAPDSPLRDVAGVLRSFEYAAYGPLVDQATDKQLAARAREW
                     VERNRAAFCDGYAVASGIDPRDSALLLGAYELDKAVYETGYETRHRPGWLPIPLRSIA
                     RLTAS"
     misc_feature    184204..185493
                     /locus_tag="BCG_0161"
                     /note="Uncharacterized protein, probably involved in
                     trehalose biosynthesis [Carbohydrate transport and
                     metabolism]; Region: Ble; COG3281"
                     /db_xref="CDD:225820"
     gene            185564..186343
                     /locus_tag="BCG_0162"
                     /db_xref="GeneID:4697426"
     CDS             185564..186343
                     /locus_tag="BCG_0162"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_976264.1"
                     /db_xref="GI:121636041"
                     /db_xref="GeneID:4697426"
                     /translation="MQREIYDGEARLSWVLAALAGILGATAFTHSAGYFVTFMTGNSQ
                     RAVLGLFGDDAWMSVTASLLILFFVAGVVIASVCRRHFWAAHPHGPTVLTTFSLIFAA
                     GVDIMLGGWHESMLDFVPILFVVFGIGALNTSFVKDGEVSVPLSYVTGTLVKMGQGIE
                     RHLAGGKVEDWLGYFLLHASFVLGAAAGGAISMVVTGPQMLAVAAVVCAATTGYTYLH
                     ADRRGLVNQKRPQPGKRLFRALRRGELDSGTSTPATNYGSS"
     misc_feature    185564..186217
                     /locus_tag="BCG_0162"
                     /note="Predicted membrane protein [Function unknown];
                     Region: COG3619"
                     /db_xref="CDD:226146"
     gene            complement(186475..187497)
                     /gene="fbpC"
                     /locus_tag="BCG_0163c"
                     /db_xref="GeneID:4697184"
     CDS             complement(186475..187497)
                     /gene="fbpC"
                     /locus_tag="BCG_0163c"
                     /standard_name="mpt45; 85C; fbpC2"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_976265.1"
                     /db_xref="GI:121636042"
                     /db_xref="GeneID:4697184"
                     /translation="MTFFEQVRRLRSAATTLPRRLAIAAMGAVLVYGLVGTFGGPATA
                     GAFSRPGLPVEYLQVPSASMGRDIKVQFQGGGPHAVYLLDGLRAQDDYNGWDINTPAF
                     EEYYQSGLSVIMPVGGQSSFYTDWYQPSQSNGQNYTYKWETFLTREMPAWLQANKGVS
                     PTGNAAVGLSMSGGSALILAAYYPQQFPYAASLSGFLNPSEGWWPTLIGLAMNDSGGY
                     NANSMWGPSSDPAWKRNDPMVQIPRLVANNTRIWVYCGNGTPSDLGGDNIPAKFLEGL
                     TLRTNQTFRDTYAADGGRNGVFNFPPNGTHSWPYWNEQLVAMKADIQHVLNGATPPAA
                     PAAPAA"
     misc_feature    complement(186514..187476)
                     /gene="fbpC"
                     /locus_tag="BCG_0163c"
                     /note="Predicted esterase [General function prediction
                     only]; Region: COG0627"
                     /db_xref="CDD:223700"
     misc_feature    complement(<186886..>187149)
                     /gene="fbpC"
                     /locus_tag="BCG_0163c"
                     /note="Esterases and lipases (includes fungal lipases,
                     cholinesterases, etc.)  These enzymes act on carboxylic
                     esters (EC: 3.1.1.-). The catalytic apparatus involves
                     three residues (catalytic triad): a serine, a glutamate or
                     aspartate and a histidine.These...; Region:
                     Esterase_lipase; cl21494"
                     /db_xref="CDD:271914"
     gene            187744..188199
                     /locus_tag="BCG_0164"
                     /db_xref="GeneID:4696522"
     CDS             187744..188199
                     /locus_tag="BCG_0164"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_976266.1"
                     /db_xref="GI:121636043"
                     /db_xref="GeneID:4696522"
                     /translation="MRTFESVADLAAAAGEKVGQSDWVTITQEEVNLFADATGDHQWI
                     HVDPERAAAGPFGTTIAHGFMTLALLPRLQHQMYTVKGVKLAINYGLNKVRFPAPVPV
                     GSRVRATSSLVGVEDLGNGTVQATVSTTVEVEGSAKPACVAESIVRYVA"
     misc_feature    187750..188196
                     /locus_tag="BCG_0164"
                     /note="NodN (nodulation factor N) contains a single hot
                     dog fold similar to those of the peroxisomal
                     Hydratase-Dehydrogenase-Epimerase (HDE) protein, and the
                     fatty acid synthase beta subunit.  Rhizobium and related
                     species form nodules on the roots of their...; Region:
                     NodN; cd03450"
                     /db_xref="CDD:239534"
     misc_feature    order(187846..187848,187861..187863,187867..187869,
                     187876..187878,187921..187923,187930..187935)
                     /locus_tag="BCG_0164"
                     /note="putative active site [active]"
                     /db_xref="CDD:239534"
     misc_feature    order(187861..187863,187867..187869,187876..187878,
                     187930..187932)
                     /locus_tag="BCG_0164"
                     /note="putative catalytic site [active]"
                     /db_xref="CDD:239534"
     gene            complement(188212..189555)
                     /gene="fadE1"
                     /locus_tag="BCG_0165c"
                     /db_xref="GeneID:4695959"
     CDS             complement(188212..189555)
                     /gene="fadE1"
                     /locus_tag="BCG_0165c"
                     /EC_number="1.3.99.-"
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-CoA dehydrogenase fadE1"
                     /protein_id="YP_976267.1"
                     /db_xref="GI:121636044"
                     /db_xref="GeneID:4695959"
                     /translation="MPVRRRAGERLPTVWDFETDPQYQSKLDWVEKFMAEELEPLDLV
                     ALDPYDKKNADTMAILRPLQRQVKDQGLWAAHLRPELGGQGFGQVKLALLNEIIGRSR
                     WAPSAFGCQAPDSGNAEILALFGTDEQKARYLRPLLDGEITSCYSMTEPQGGSDPGLF
                     VTAATRDAAGNGDWIINGEKWFSTNAKHASFFIVMAVTKPEARTYEKMSLFIVPADTP
                     GIEIVRNVGVGAESTRHASHGYIRYHDVRVPADHVLGGEGQAFMIAQTRLGGGRIHHA
                     MRTIALARRAFDMMCERALSRQTRHGRLADLQMTQEKIADSWIQIEQFRLLVLRTAWL
                     IDKHHDYQKVRRDIAAVKVAMPQVLHDVVQRAMHLHGALGVSDEMPFVKMMLAAESLG
                     IADGATELHKMTVARRTLREYQPVTTLFPSQHIPTRRAHAEAWLAQRLEHAIAEF"
     misc_feature    complement(188311..189510)
                     /gene="fadE1"
                     /locus_tag="BCG_0165c"
                     /note="Acyl-CoA dehydrogenases [Lipid metabolism]; Region:
                     CaiA; COG1960"
                     /db_xref="CDD:224871"
     misc_feature    complement(188323..189486)
                     /gene="fadE1"
                     /locus_tag="BCG_0165c"
                     /note="Acyl-CoA dehydrogenase; Region: ACAD; cl09933"
                     /db_xref="CDD:271680"
     misc_feature    complement(order(188359..188361,188365..188367,
                     188371..188379,189004..189006,189010..189012,
                     189112..189114,189118..189120,189208..189210))
                     /gene="fadE1"
                     /locus_tag="BCG_0165c"
                     /note="active site"
                     /db_xref="CDD:173838"
     gene            complement(189597..190679)
                     /gene="fgd2"
                     /locus_tag="BCG_0166c"
                     /db_xref="GeneID:4695872"
     CDS             complement(189597..190679)
                     /gene="fgd2"
                     /locus_tag="BCG_0166c"
                     /EC_number="1.-.-.-"
                     /note="Differs from Rv0132c by 1aa, E147K"
                     /codon_start=1
                     /transl_table=11
                     /product="F420-dependent glucose-6-phosphate
                     dehydrogenase"
                     /protein_id="YP_976268.1"
                     /db_xref="GI:121636045"
                     /db_xref="GeneID:4695872"
                     /translation="MTGISRRTFGLAAGFGAIGAGGLGGGCSTRSGPTPTPEPASRGV
                     GVVLSHEQFRTDRLVAHAQAAEQAGFRYVWASDHLQPWQDNEGHSMFPWLTLALVGNS
                     TSSILFGTGVTCPIYRYHPATVAQAFASLAILNPGRVFLGLGTGERLNEQAATDTFGN
                     YRERHDRLIEAIVLIRQLWSGERISFTGHYFRTDELKLYDTPAMPPPIFVAASGPQSA
                     TLAGRYGDGWIAQARDINDAKLLAAFAAGAQAAGRDPTTLGKRAELFAVVGDDKAAAR
                     AADLWRFTAGAVDQPNPVEIQRAAESNPIEKVLANWAVGTDPGVHIGAVQAVLDAGAV
                     PFLHFPQDDPITAIDFYRTNVLPELR"
     misc_feature    complement(<190248..190577)
                     /gene="fgd2"
                     /locus_tag="BCG_0166c"
                     /note="Flavin-utilizing monoxygenases; Region:
                     Flavin_utilizing_monoxygenases; cl19096"
                     /db_xref="CDD:271834"
     misc_feature    complement(<189984..190547)
                     /gene="fgd2"
                     /locus_tag="BCG_0166c"
                     /note="N5,N10-methylenetetrahydromethanopterin reductase
                     (Mer) catalyzes the reduction of
                     N5,N10-methylenetetrahydromethanopterin with reduced
                     coenzyme F420 to N5-methyltetrahydromethanopterin and
                     oxidized coenzyme F420; Region:
                     Tetrahydromethanopterin_reductase; cd01097"
                     /db_xref="CDD:238530"
     gene            190766..191248
                     /locus_tag="BCG_0167"
                     /db_xref="GeneID:4695794"
     CDS             190766..191248
                     /locus_tag="BCG_0167"
                     /EC_number="2.3.1.-"
                     /note="In Mycobacterium tuberculosis strain H37Rv, and
                     Mycobacterium bovis AF2122/97, codon 161 is TAC and in
                     Mycobacterium bovis BCG Pasteur, TAA"
                     /codon_start=1
                     /transl_table=11
                     /product="acetyltransferase"
                     /protein_id="YP_976269.1"
                     /db_xref="GI:121636046"
                     /db_xref="GeneID:4695794"
                     /translation="MTPQARPARRADVRELSRTMARAFYDDPFMSWLLSNDNARTARL
                     TRLFATIVRHQHLAGGGVEVARGAAGIGGAALWDPPDRWRESRRQQLAMTPGFLRVFG
                     FRTAKARAALDVMMRVHPEEPHWYLAAIGSDPTVRGQGFGQVLMRSRLDRCDAEHCPA
                     "
     misc_feature    <191105..191242
                     /locus_tag="BCG_0167"
                     /note="N-Acyltransferase superfamily: Various enzymes that
                     characteristically catalyze the transfer of an acyl group
                     to a substrate; Region: NAT_SF; cd04301"
                     /db_xref="CDD:173926"
     misc_feature    order(191153..191161,191189..191194)
                     /locus_tag="BCG_0167"
                     /note="Coenzyme A binding pocket [chemical binding]; other
                     site"
                     /db_xref="CDD:173926"
     gene            191668..192051
                     /locus_tag="BCG_0168"
                     /pseudo
                     /db_xref="GeneID:4698881"
     misc_feature    191668..192051
                     /locus_tag="BCG_0168"
                     /pseudo
     gene            192051..192158
                     /locus_tag="BCG_0169"
                     /pseudo
                     /db_xref="GeneID:4696383"
     misc_feature    192051..192158
                     /locus_tag="BCG_0169"
                     /pseudo
     gene            192160..192570
                     /locus_tag="BCG_0170"
                     /pseudo
                     /db_xref="GeneID:4695611"
     misc_feature    192160..192570
                     /locus_tag="BCG_0170"
                     /note="differs from Mb0139-3 by 1aa, G16R"
                     /pseudo
     gene            complement(192541..193146)
                     /locus_tag="BCG_0171c"
                     /db_xref="GeneID:4696778"
     CDS             complement(192541..193146)
                     /locus_tag="BCG_0171c"
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulatory protein"
                     /protein_id="YP_976270.1"
                     /db_xref="GI:121636047"
                     /db_xref="GeneID:4696778"
                     /translation="MTAVAAGALVVETDSFRLRLLDGLVASIGERGYRATTVSDIVRH
                     ARTSKRTFYDRFTSKEQCFLELLLADNETLGNSIRAAVDPNADWHDQIRQAVEAYVTH
                     IESRPAVTLSWIREFPSLGAAAYPVQRRGMEQLTSLLIELSASPGFRRANLPPLNVPL
                     AVILLGGLRELTALTVEDGQPIRNIVEPAVDASIALLGPRS"
     misc_feature    complement(192544..193113)
                     /locus_tag="BCG_0171c"
                     /note="Transcriptional regulator [Transcription]; Region:
                     AcrR; COG1309"
                     /db_xref="CDD:224228"
     misc_feature    complement(192949..193089)
                     /locus_tag="BCG_0171c"
                     /note="Bacterial regulatory proteins, tetR family; Region:
                     TetR_N; pfam00440"
                     /db_xref="CDD:249860"
     gene            193263..194588
                     /gene="cyp138"
                     /locus_tag="BCG_0172"
                     /db_xref="GeneID:4696345"
     CDS             193263..194588
                     /gene="cyp138"
                     /locus_tag="BCG_0172"
                     /EC_number="1.14.-.-"
                     /codon_start=1
                     /transl_table=11
                     /product="cytochrome p450 138 cyp138"
                     /protein_id="YP_976271.1"
                     /db_xref="GI:121636048"
                     /db_xref="GeneID:4696345"
                     /translation="MSEVVTAAPAPPVVRLPPAVRGPKLFQGLAFVVSRRRLLGRFVR
                     RYGKAFTANILMYGRVVVVADPQLARQVFTSSPEELGNIQPNLSRMFGSGSVFALDGD
                     DHRRRRRLLAPPFHGKSMKNYETIIEEETLRETANWPQGQAFATLPSMMHITLNAILR
                     AIFGAGGSELDELRRLIPPWVTLGSRLAALPKPKRDYGRLSPWGRLAEWRRQYDTVID
                     KLIEAERADPNFADRTDVLALMLRSTYDDGSIMSRKDIGDELLTLLAAGHETTAATLG
                     WAFERLSRHPDVLAALVEEVDNGGHELRQAAILEVQRARTVIDFAARRVNPPVYQLGE
                     WVIPRGYSIIINIAQIHGDPDVFPQPDRFDPQRYIGSKPSPFAWIPFGGGTRRCVGAA
                     FANMEMDVVLRTVLRHFTLETTTAAGERSHGRGVAFTPKDGGRVVMRRR"
     misc_feature    193311..194585
                     /gene="cyp138"
                     /locus_tag="BCG_0172"
                     /note="Cytochrome P450 [Secondary metabolites
                     biosynthesis, transport, and catabolism]; Region: CypX;
                     COG2124"
                     /db_xref="CDD:225035"
     gene            complement(194609..195157)
                     /gene="msrA"
                     /locus_tag="BCG_0173c"
                     /db_xref="GeneID:4696607"
     CDS             complement(194609..195157)
                     /gene="msrA"
                     /locus_tag="BCG_0173c"
                     /EC_number="1.8.4.11"
                     /note="this stereospecific enzymes reduces the S isomer of
                     methionine sulfoxide while MsrB reduces the R form;
                     provides protection against oxidative stress"
                     /codon_start=1
                     /transl_table=11
                     /product="methionine sulfoxide reductase A"
                     /protein_id="YP_976272.1"
                     /db_xref="GI:121636049"
                     /db_xref="GeneID:4696607"
                     /translation="MTSNQKAILAGGCFWGLQDLIRNQPGVVSTRVGYSGGNIPNATY
                     RNHGTHAEAVEIIFDPTVTDYRTLLEFFFQIHDPTTKDRQGNDRGTSYRSAIFYFDEQ
                     QKRIALDTIADVEASGLWPGKVVTEVSPAGDFWEAEPEHQDYLQRYPNGYTCHFVRPG
                     WRLPRRTAESALRASLSPELGT"
     misc_feature    complement(194660..195154)
                     /gene="msrA"
                     /locus_tag="BCG_0173c"
                     /note="methionine sulfoxide reductase A; Provisional;
                     Region: PRK14054"
                     /db_xref="CDD:237597"
     gene            195220..195723
                     /locus_tag="BCG_0174"
                     /db_xref="GeneID:4697736"
     CDS             195220..195723
                     /locus_tag="BCG_0174"
                     /note="Differs from Mb0143 by 1aa, D96G"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_976273.1"
                     /db_xref="GI:121636050"
                     /db_xref="GeneID:4697736"
                     /translation="MSASEFSRAELAAAFEKFEKTVARAAATRDWDCWVQHYTPDVEY
                     IEHAAGIMRGRQRVRAWIQETMTTFPGSHMVAFPSLWSVIDESTGRIICELDNPMLDP
                     GDGSVISATNISIITYAGNGQWCRQEDIYNPLRFLRAAMKWCRKAQELGTLDEDAARW
                     MRRHGGP"
     misc_feature    195289..195597
                     /locus_tag="BCG_0174"
                     /note="SnoaL-like domain; Region: SnoaL_2; pfam12680"
                     /db_xref="CDD:257217"
     gene            195724..196746
                     /locus_tag="BCG_0175"
                     /db_xref="GeneID:4697886"
     CDS             195724..196746
                     /locus_tag="BCG_0175"
                     /EC_number="1.-.-.-"
                     /note="Differs from Rv0139 by 1aa, R227H"
                     /codon_start=1
                     /transl_table=11
                     /product="oxidoreductase"
                     /protein_id="YP_976274.1"
                     /db_xref="GI:121636051"
                     /db_xref="GeneID:4697886"
                     /translation="MNAPKLVIGANGFLGSHVTRQLVADCAPQKGEVRAMVRPAANTR
                     SIDDLPLTRFHGDVFDTATVAEAMAGCDDVYYCVVDTRAWLRDPSPLFRTNVAGLRNV
                     LDVATDASLRRFVFTSSYATVGRRRGHVATEEDRVDTRKVTPYVRSRVAAEDLVLQYA
                     HDAGLPAVAMCVSTTYGGGDWGRTPHGAFIAGAVFGRLPFTMRGIRLEAVGVDDAARA
                     LILAAERGRNGERYLISERMMPLQEVVRIAADEAGVPPPRWSISVPVLYALGALGSLR
                     ARLTGKDTELSLASVRMMRSEADVDHGKAVRELGWQPRPVEESIREAARFWAAMRTVG
                     KDPAAS"
     misc_feature    195733..196710
                     /locus_tag="BCG_0175"
                     /note="hopanoid-associated sugar epimerase; Region: HpnA;
                     TIGR03466"
                     /db_xref="CDD:163279"
     misc_feature    195739..196698
                     /locus_tag="BCG_0175"
                     /note="Short-chain dehydrogenases/reductases (SDR);
                     Region: SDR; cl21454"
                     /db_xref="CDD:271874"
     misc_feature    order(195748..195750,195754..195759,195763..195765,
                     195832..195840,195952..195960,196072..196080,
                     196156..196158,196168..196170,196237..196248)
                     /locus_tag="BCG_0175"
                     /note="NAD(P) binding site [chemical binding]; other site"
                     /db_xref="CDD:187535"
     misc_feature    order(196006..196008,196078..196080,196156..196158,
                     196168..196170)
                     /locus_tag="BCG_0175"
                     /note="active site"
                     /db_xref="CDD:187535"
     gene            196807..197187
                     /locus_tag="BCG_0176"
                     /db_xref="GeneID:4696471"
     CDS             196807..197187
                     /locus_tag="BCG_0176"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_976275.1"
                     /db_xref="GI:121636052"
                     /db_xref="GeneID:4696471"
                     /translation="MSNRIVLEPSADHPITIEPTNRRVQVRVNGEVVADTAAALCLQE
                     ASYPAVQYIPLADVVQDRLIRTETSTYCPFKGEASYYSVTTDAGDIVDDVMWTYENPY
                     PAVAAIAGHVACYPDKAEISIFPG"
     misc_feature    196807..197184
                     /locus_tag="BCG_0176"
                     /note="Uncharacterized protein conserved in bacteria
                     [Function unknown]; Region: COG2343"
                     /db_xref="CDD:225220"
     gene            complement(197168..197578)
                     /locus_tag="BCG_0177c"
                     /db_xref="GeneID:4697244"
     CDS             complement(197168..197578)
                     /locus_tag="BCG_0177c"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_976276.1"
                     /db_xref="GI:121636053"
                     /db_xref="GeneID:4697244"
                     /translation="MTPFDDPQAELAWMFLQSLCEGGDLDEGFALLSNDFTYWSIVTR
                     TELDKKTFRRAVERRKQVFEVNIELIRCVNEGETVVVEGHCDGVSADRTRYDSPFVCI
                     FETRDGMIISLREYSDTQSLAEVYPVACATPGRC"
     misc_feature    complement(197171..197566)
                     /locus_tag="BCG_0177c"
                     /note="Ketosteroid isomerase-related protein [General
                     function prediction only]; Region: COG3631"
                     /db_xref="CDD:226158"
     gene            197608..198534
                     /locus_tag="BCG_0178"
                     /db_xref="GeneID:4695477"
     CDS             197608..198534
                     /locus_tag="BCG_0178"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_976277.1"
                     /db_xref="GI:121636054"
                     /db_xref="GeneID:4695477"
                     /translation="MRSIDVVVEAVVTFAGAAGFAHTLAPLRRGQQDPCFRVPGDGTI
                     WRTSLLPTGPVTARISRAGRDAARCVAWGSGAEEFVDMAPAMLGAADDASDFVPLHPA
                     VAAAHRRLPNLRLGRTGQVLEALIPAVIEQRVPGADAFRSWRLLVSKYGTQAPGPAPP
                     GMRVPPSAEVWRHIPSWEFHRANVDPGRARAVVGCAQRAASLERLVSLPAARAAEALT
                     SLPGVGVWTAAETTQRVFGDADAVSVGDYHIPKMIGWTLVGRPVDDAGMLELLEPMRP
                     HRHRVVRLLEASGLAREPRRGPRLPVQNIRAL"
     misc_feature    197641..198510
                     /locus_tag="BCG_0178"
                     /note="3-methyladenine DNA glycosylase/8-oxoguanine DNA
                     glycosylase [DNA replication, recombination, and repair];
                     Region: AlkA; COG0122"
                     /db_xref="CDD:223200"
     misc_feature    197974..198453
                     /locus_tag="BCG_0178"
                     /note="endonuclease III; includes endonuclease III
                     (DNA-(apurinic or apyrimidinic site) lyase), alkylbase DNA
                     glycosidases (Alka-family) and other DNA glycosidases;
                     Region: ENDO3c; cd00056"
                     /db_xref="CDD:238013"
     misc_feature    order(198004..198012,198019..198021,198169..198171)
                     /locus_tag="BCG_0178"
                     /note="minor groove reading motif; other site"
                     /db_xref="CDD:238013"
     misc_feature    198265..198288
                     /locus_tag="BCG_0178"
                     /note="helix-hairpin-helix signature motif; other site"
                     /db_xref="CDD:238013"
     misc_feature    198343..198345
                     /locus_tag="BCG_0178"
                     /note="active site"
                     /db_xref="CDD:238013"
     gene            complement(198601..200079)
                     /locus_tag="BCG_0179c"
                     /db_xref="GeneID:4696266"
     CDS             complement(198601..200079)
                     /locus_tag="BCG_0179c"
                     /note="Differs from Rv0143c by 1aa, L34F"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_976278.1"
                     /db_xref="GI:121636055"
                     /db_xref="GeneID:4696266"
                     /translation="MAPGDWSVFAWHAANLPTMPEAEDIGNEAAGGRLGVSIRSAGYL
                     RKWFLLGITIGVIAGLGAVVFYLALKYTSEFLLGYLADYQIPTPVGEGGHRGSTGFAR
                     PWAIPLVTTGGAVLSALIVAKLAPEATGHGTDEAIESVHGDPRAIRGRAVLVKMVASA
                     LTIGSGGSGGREGPTAQISAGFCSLLTRRLNLSNEDGRTAVALGIGAGIGAIFAAPLG
                     GAALGASIPYRDDFDYRNLLPGFIASGTAYAVLGAFLGFDPLFGYIDAEYRFEKAWPL
                     LWFVVIGLIAAAVGYLYARVFHASVAITRRLPGGPVLKPAIGGLLVGLLGLPIPQILS
                     SGYGWAQLAADRGTLLSIPLWIVIVLPIAKILATSLSIGTGGSGGLFGPGIVIGAFVG
                     AAIWRLGELTELPGVPHEPGIFVVVAMMACFGSVSRAPLAVMIMVAEMTGSFSVVPGA
                     IIAVGIAALLLSRTNVTIYETQRLNRQTAEAERGGSDRPTTA"
     misc_feature    complement(198709..199917)
                     /locus_tag="BCG_0179c"
                     /note="CLC voltage-gated chloride channel. The ClC
                     chloride channels catalyse the selective flow of Cl- ions
                     across cell membranes, thereby regulating electrical
                     excitation in skeletal muscle and the flow of salt and
                     water across epithelial barriers. This...; Region:
                     Voltage_gated_ClC; cd00400"
                     /db_xref="CDD:238233"
     misc_feature    complement(order(198931..198945,199558..199572,
                     199663..199677))
                     /locus_tag="BCG_0179c"
                     /note="Cl- selectivity filter; other site"
                     /db_xref="CDD:238233"
     misc_feature    complement(order(198937..198945,199561..199566,
                     199666..199668,199672..199674))
                     /locus_tag="BCG_0179c"
                     /note="Cl- binding residues [ion binding]; other site"
                     /db_xref="CDD:238233"
     misc_feature    complement(199564..199566)
                     /locus_tag="BCG_0179c"
                     /note="pore gating glutamate residue; other site"
                     /db_xref="CDD:238233"
     misc_feature    complement(order(198715..198720,198739..198741,
                     198763..198765,198787..198789,198796..198798,
                     199333..199335,199354..199356,199402..199404,
                     199429..199431))
                     /locus_tag="BCG_0179c"
                     /note="dimer interface [polypeptide binding]; other site"
                     /db_xref="CDD:238233"
     gene            200181..201023
                     /locus_tag="BCG_0180"
                     /db_xref="GeneID:4697048"
     CDS             200181..201023
                     /locus_tag="BCG_0180"
                     /codon_start=1
                     /transl_table=11
                     /product="TetR family transcriptional regulator"
                     /protein_id="YP_976279.1"
                     /db_xref="GI:121636056"
                     /db_xref="GeneID:4697048"
                     /translation="MPHSWTPTSVMTPPLVVAAFRPVGHYRLATDRAGGPCSPPATGA
                     KLTSSVASRPTVGTKPQWWHTLVMSMSLTAGRGPGRPPAAKADETRKRILHAARQVFS
                     ERGYDGATFQEIAVRADLTRPAINHYFANKRVLYQEVVEQTHELVIVAGIERARREPT
                     LMGRLAVVVDFAMEADAQYPASTAFLATTVLESQRHPELSRTENDAVRATREFLVWAV
                     NDAIERGELAADVDVSSLAETLLVVLCGVGFYIGFVGSYQRMATITDSFQQLLAGTLW
                     RPPT"
     misc_feature    200418..200957
                     /locus_tag="BCG_0180"
                     /note="Transcriptional regulator [Transcription]; Region:
                     AcrR; COG1309"
                     /db_xref="CDD:224228"
     misc_feature    200457..200597
                     /locus_tag="BCG_0180"
                     /note="Bacterial regulatory proteins, tetR family; Region:
                     TetR_N; pfam00440"
                     /db_xref="CDD:249860"
     gene            201112..202065
                     /locus_tag="BCG_0181"
                     /db_xref="GeneID:4696148"
     CDS             201112..202065
                     /locus_tag="BCG_0181"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_976280.1"
                     /db_xref="GI:121636057"
                     /db_xref="GeneID:4696148"
                     /translation="MTELDDVSSLPSSRRTAGDTWAITESVGATALGVAAARAVETAA
                     TNPLIRDEFAKVLVSSAGTAWARLADADLAWLDGDQLGRRVHRVACDYQAVRTHFFDE
                     YFGAAVDAGVRQVVILAAGLDARAYRLNWPAGTVVYEIDQPSVLEYKAGILQSHGAVP
                     TARRHAVAVDLRDDWPAALIAAGFDGTQPTAWLAEGLLPYLPGDAADRLFDMVTALSA
                     PGSQVAVEAFTMNTKGNTQRWNRMRERLGLDIDVQALTYHEPDRSDAAQWLATHGWQV
                     HSVSNREEMARLGRAIPQDLVDETVRTTLLRGRLVTPAQPA"
     misc_feature    201151..202047
                     /locus_tag="BCG_0181"
                     /note="O-Methyltransferase involved in polyketide
                     biosynthesis [Secondary metabolites biosynthesis,
                     transport, and catabolism]; Region: COG3315"
                     /db_xref="CDD:225852"
     gene            202108..203040
                     /locus_tag="BCG_0182"
                     /db_xref="GeneID:4695365"
     CDS             202108..203040
                     /locus_tag="BCG_0182"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_976281.1"
                     /db_xref="GI:121636058"
                     /db_xref="GeneID:4695365"
                     /translation="MRTHDDTWDIKTSVGATAVMVAAARAVETDRPDPLIRDPYARLL
                     VTNAGAGAIWEAMLDPTLVAKAAAIDAETAAIVAYLRSYQAVRTNFFDTYFASAVAAG
                     IRQVVILASGLDSRAYRLDWPAGTIVYEIDQPKVLSYKSTTLAENGVTPSAGRREVPA
                     DLRQDWPAALRDAGFDPTARTAWLAEGLLMYLPAEAQDRLFTQVGAVSVAGSRIAAET
                     APVHGEERRAEMRARFKKVADVLGIEQTIDVQELVYHDQDRASVADWLTDHGWRARSQ
                     RAPDEMRRVGRWVEGVPMADDPTAFAEFVTAERL"
     misc_feature    202189..202971
                     /locus_tag="BCG_0182"
                     /note="methyltransferase, TIGR00027 family; Region:
                     mthyl_TIGR00027"
                     /db_xref="CDD:232789"
     gene            203135..204655
                     /locus_tag="BCG_0183"
                     /db_xref="GeneID:4695675"
     CDS             203135..204655
                     /locus_tag="BCG_0183"
                     /EC_number="1.2.1.-"
                     /codon_start=1
                     /transl_table=11
                     /product="aldehyde dehydrogenase"
                     /protein_id="YP_976282.1"
                     /db_xref="GI:121636059"
                     /db_xref="GeneID:4695675"
                     /translation="MSDRVKAVAPPDGRTMMTTESVARKTQKSETEAPREPAPVSDEK
                     QTDVAKTVARLRKTFASGRTRSVEWRKQQLRALQKLMDENEDAIAAALAEDLDRNPFE
                     AYLADIATTSAEAKYAAKRVRRWMRRRYLLLEVPQLPGRGWVEYEPYGTVLIIGAWNY
                     PFYLTLGPAVGAIAAGNAVVLKPSEIAAASAHLMTELVYRYLDTEAIAVVQGDGAVSQ
                     ELIAQGFDRVMFTGGTEIGRKVYEGAAPHLTPVTLELGGKSPVIVAADADVDVAAKRI
                     AWIKLLNAGQTCVAPDYVLADATVRDELVSKITAALTKFRSGAPQGMRIVNQRQFDRL
                     SGYLAAAKTDAAADGGGVVVGGDCDASNLRIQPTVVVDPDPDGPLMSNEIFGPILPVV
                     TVKSLDDAIRFVNSRPKPLSAYLFTKSRAVRERVIREVPAGGMMVNHLAFQVSTAKLP
                     FGGVGASGMGAYHGRWGFEEFSHRKSVLTKPTRPDLSSFIYPPYTERAIKVARRLF"
     misc_feature    203285..204571
                     /locus_tag="BCG_0183"
                     /note="ALDH subfamily: Coniferyl aldehyde dehydrogenase,
                     ALDH families 3, 13, and 14, and other related proteins;
                     Region: ALDH_F3-13-14_CALDH-like; cd07087"
                     /db_xref="CDD:143406"
     misc_feature    order(203603..203611,203687..203689,203774..203776,
                     203828..203830,204113..204115,204119..204124,
                     204131..204133,204281..204283,204287..204289)
                     /locus_tag="BCG_0183"
                     /note="NAD(P) binding site [chemical binding]; other site"
                     /db_xref="CDD:143406"
     misc_feature    order(203609..203611,203894..203896,203987..203989,
                     203996..203998)
                     /locus_tag="BCG_0183"
                     /note="catalytic residues [active]"
                     /db_xref="CDD:143406"
     gene            204730..205590
                     /locus_tag="BCG_0184"
                     /db_xref="GeneID:4697099"
     CDS             204730..205590
                     /locus_tag="BCG_0184"
                     /EC_number="1.-.-.-"
                     /codon_start=1
                     /transl_table=11
                     /product="short-chain type dehydrogenase/reductase"
                     /protein_id="YP_976283.1"
                     /db_xref="GI:121636060"
                     /db_xref="GeneID:4697099"
                     /translation="MPGVQDRVIVVTGAGGGLGREYALTLAGEGASVVVNDLGGARDG
                     TGAGSAMADEVVAEIRDKGGRAVANYDSVATEDGAANIIKTALDEFGAVHGVVSNAGI
                     LRDGTFHKMSFENWDAVLKVHLYGGYHVLRAAWPHFREQSYGRVVVATSTSGLFGNFG
                     QTNYGAAKLGLVGLINTLALEGAKYNIHANALAPIAATRMTQDILPPEVLEKLTPEFV
                     APVVAYLCTEECADNASVYVVGGGKVQRVALFGNDGANFDKPPSVQDVAARWAEITDL
                     SGAKIAGFKL"
     misc_feature    204730..205464
                     /locus_tag="BCG_0184"
                     /note="short chain dehydrogenase; Provisional; Region:
                     PRK07791"
                     /db_xref="CDD:236099"
     misc_feature    204739..205455
                     /locus_tag="BCG_0184"
                     /note="(3R)-hydroxyacyl-CoA dehydrogenase-like,
                     classical(c)-like SDRs; Region:
                     hydroxyacyl-CoA-like_DH_SDR_c-like; cd05353"
                     /db_xref="CDD:187611"
     misc_feature    order(204766..204768,204775..204783,204835..204843,
                     204847..204849,204943..204948,205024..205035,
                     205093..205098,205174..205182,205219..205221,
                     205231..205233,205309..205317,205321..205332)
                     /locus_tag="BCG_0184"
                     /note="NAD binding site [chemical binding]; other site"
                     /db_xref="CDD:187611"
     misc_feature    order(204814..204816,205048..205056,205060..205068,
                     205075..205080,205087..205089,205099..205104,
                     205111..205113,205120..205125,205132..205137,
                     205183..205209,205213..205215,205222..205227,
                     205234..205239,205243..205251,205255..205263,
                     205267..205272,205276..205281,205285..205287,
                     205354..205356,205363..205368,205378..205380,
                     205387..205392,205396..205404,205423..205425,
                     205435..205443,205447..205455)
                     /locus_tag="BCG_0184"
                     /note="homodimer interface [polypeptide binding]; other
                     site"
                     /db_xref="CDD:187611"
     misc_feature    order(205096..205098,205180..205182,205219..205221,
                     205231..205233)
                     /locus_tag="BCG_0184"
                     /note="active site"
                     /db_xref="CDD:187611"
     gene            205597..206565
                     /locus_tag="BCG_0185"
                     /db_xref="GeneID:4698796"
     CDS             205597..206565
                     /locus_tag="BCG_0185"
                     /EC_number="1.6.5.-"
                     /codon_start=1
                     /transl_table=11
                     /product="quinone oxidoreductase"
                     /protein_id="YP_976284.1"
                     /db_xref="GI:121636061"
                     /db_xref="GeneID:4698796"
                     /translation="MKACVVKELSGPSGMVYTDIDEVSGDGGKVVIDVRAAGVCFPDL
                     LLTKGEYQLKLTPPFVPGMETAGVVRSAPSDAGFHVGERVSAFGVLGGYAEQIAVPVA
                     NVVRSPVELDDAGAVSLLVNYNTMYFALARRAALRPGDTVLVLGAAGGVGTAAVQIAK
                     AMQAGKVIAMVHREGAIDYVASLGADVVLPLTEGWAQQVRDHTYGQGVDIVVDPIGGP
                     TFDDALGVLAIDGKLLLIGFAAGAVPTLKVNRLLVRNISVVGVGWGEYLNAVPGSAAL
                     FAWGLNQLVFLGLRPPPPQRYPLSEAQAALQSLDDGGVLGKVVLEP"
     misc_feature    205597..206562
                     /locus_tag="BCG_0185"
                     /note="NADPH:quinone reductase and related Zn-dependent
                     oxidoreductases [Energy production and conversion /
                     General function prediction only]; Region: Qor; COG0604"
                     /db_xref="CDD:223677"
     misc_feature    205597..206559
                     /locus_tag="BCG_0185"
                     /note="Quinone oxidoreductase (QOR); Region: QOR1;
                     cd08241"
                     /db_xref="CDD:176203"
     misc_feature    order(205714..205719,205957..205959,205969..205971,
                     206032..206034,206041..206049,206107..206112,
                     206122..206124,206167..206169,206236..206238,
                     206302..206307,206311..206316,206377..206385,
                     206530..206532,206536..206538,206542..206544)
                     /locus_tag="BCG_0185"
                     /note="NAD(P) binding site [chemical binding]; other site"
                     /db_xref="CDD:176203"
     gene            complement(206562..206849)
                     /locus_tag="BCG_0186c"
                     /db_xref="GeneID:4697427"
     CDS             complement(206562..206849)
                     /locus_tag="BCG_0186c"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_976285.1"
                     /db_xref="GI:121636062"
                     /db_xref="GeneID:4697427"
                     /translation="MLTLPDDRAPTGLPDPGIEALAHTKIASTISTVVADGYAVVLST
                     ADIANSLLANAIGYPIAASVALVTPAAGANSSCWPADPSQHHRIAESRACA"
     gene            complement(207440..209206)
                     /gene="PE1"
                     /locus_tag="BCG_0187c"
                     /db_xref="GeneID:4697778"
     CDS             complement(207440..209206)
                     /gene="PE1"
                     /locus_tag="BCG_0187c"
                     /note="Differs from Rv0151c by 1aa, R26G"
                     /codon_start=1
                     /transl_table=11
                     /product="PE family protein"
                     /protein_id="YP_976286.1"
                     /db_xref="GI:121636063"
                     /db_xref="GeneID:4697778"
                     /translation="MAPFGFTPKARHNRGVALRSTYRLDRWVMGPVDKEGWGLSYVFA
                     QPSVLAAAATDLAGIGSAINQATAAVAAPTTGLAAAAADEVSTALATLFGAYGQQFQA
                     ISAQVAAFHNEFTQRLAAAANAFVNAEATNTSALVQEATAGLFKPTSPPVLPPMFNQN
                     TAIIMGGTGSPIPTPSYVNAITTLFIDPVVSNPVVKALVTPEELYPITGVKSLPFQTS
                     VQLGLQILDGAIWEQINAGNHVTVFGYSQSAVIASLEMQHLISLGPNAPSPSQLNFIL
                     IGNEMNPNGGILARIPGLNVTTLGLPFYGATPDNPYPTTTYTLEYDGFADFPRYPLNV
                     LSDINAVFGILTVHTTYADLTPAQIASATQLPTQGTTSNTYYIIETEHLPLLAPLRAI
                     PVIGPPLAALVEPNLEVIVNLGYGDPRFGYSTSPANVPTPFGLFPDVPASVVADALVA
                     GTQQGVNDFMVELPAALNTLPQTPMPAFPPYVPTLLPPPPPPQPATLINIADTFASVV
                     STGYSILLPTADLGLAFVTILPAYDLTLFVNQLAAGNLRAAIELPLAATIGLAALGGM
                     IEFIAIVVTLADITQQLQSFSI"
     misc_feature    complement(208853..209089)
                     /gene="PE1"
                     /locus_tag="BCG_0187c"
                     /note="PE family; Region: PE; pfam00934"
                     /db_xref="CDD:250239"
     misc_feature    complement(207959..208618)
                     /gene="PE1"
                     /locus_tag="BCG_0187c"
                     /note="PE-PPE domain; Region: PE-PPE; pfam08237"
                     /db_xref="CDD:254681"
     gene            complement(209216..210793)
                     /gene="PE2"
                     /locus_tag="BCG_0188c"
                     /db_xref="GeneID:4695743"
     CDS             complement(209216..210793)
                     /gene="PE2"
                     /locus_tag="BCG_0188c"
                     /codon_start=1
                     /transl_table=11
                     /product="PE family protein"
                     /protein_id="YP_976287.1"
                     /db_xref="GI:121636064"
                     /db_xref="GeneID:4695743"
                     /translation="MRCRPPSRNRSAHTARNTRPCSLKSRRFTVRFHQTLAAAANSYA
                     DAEAAIASTRQNQLAVPAAAPTPAAAAMIPPFPANLTTLFFGPTGIPLPPPSMLTPPI
                     RCRSVRRALQAVFTPEELYPLTGVRSLVLNTSVEEGLTILHDAIMVELATTGNAVTVF
                     GWSQSAIIASLEMQRFTAMGGAAPSASDLNFVLVGNEMNPNGGMLARFPDLTLPTLDL
                     TFYGATPSDTIYPTAIYTLEYDGFADFSRYPLNFISDLNAVAGITFVHTKYLDLTPAQ
                     VEGATKLPTSPGYTGVTDYYIIRTENRPLLQPLRAVPVIGDPLADLIQPNLKVIVNLG
                     YGDPNYGYSTSYADVRTPFGLWPNVPPQVIADALAAGTQEGILDFTADLQALSAQPLT
                     LPQIQLPQPADLVAAVAAAPTPAEVVNTLARIISTNYAVLLPTVDIALALVTTLPLYT
                     TQLFVRQLAAGNLINAIGYPLAATVGLGTIDSGRRGIAHPPRGGLGHRSKHRGPRHLT
                     DSRRHRRPPTTVYRPRQ"
     misc_feature    complement(209786..210460)
                     /gene="PE2"
                     /locus_tag="BCG_0188c"
                     /note="PE-PPE domain; Region: PE-PPE; pfam08237"
                     /db_xref="CDD:254681"
     gene            complement(211052..211882)
                     /gene="ptbB"
                     /locus_tag="BCG_0189c"
                     /db_xref="GeneID:4699376"
     CDS             complement(211052..211882)
                     /gene="ptbB"
                     /locus_tag="BCG_0189c"
                     /EC_number="3.1.3.48"
                     /standard_name="MPtpB"
                     /note="Differs from Rv0153c by 1aa, G105D"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphotyrosine protein phosphatase ptpB"
                     /protein_id="YP_976288.1"
                     /db_xref="GI:121636065"
                     /db_xref="GeneID:4699376"
                     /translation="MAVRELPGAWNFRDVADTATALRPGRLFRSSELSRLDDAGRATL
                     RRLGITDVADLRSSREVARRGPGRVPDGIDVHLLPFPDLADDDADDSAPHETAFKRLL
                     TNGGSNGESGESSQSINDAATRYMTDEYRQFPTRNGAQRALHRVVTLLAAGRPVLTHC
                     FAGKDRTGFVVALVLEAVGLDRDVIVADYLRSNDSVPQLRARISEMIQQRFDTELAPE
                     VVTFTKARLSDGVLGVRAEYLAAARQTIDETYGSLGGYLRDAGISQATVNRMRGVLLG
                     "
     misc_feature    complement(211067..211882)
                     /gene="ptbB"
                     /locus_tag="BCG_0189c"
                     /note="Protein tyrosine/serine phosphatase [Signal
                     transduction mechanisms]; Region: COG2365"
                     /db_xref="CDD:225240"
     misc_feature    complement(211304..211852)
                     /gene="ptbB"
                     /locus_tag="BCG_0189c"
                     /note="Tyrosine phosphatase family; Region:
                     Y_phosphatase3; pfam13350"
                     /db_xref="CDD:257679"
     misc_feature    complement(211058..>211192)
                     /gene="ptbB"
                     /locus_tag="BCG_0189c"
                     /note="Tyrosine phosphatase family C-terminal region;
                     Region: Y_phosphatase3C; pfam13348"
                     /db_xref="CDD:257677"
     gene            complement(211884..213095)
                     /gene="fadE2"
                     /locus_tag="BCG_0190c"
                     /db_xref="GeneID:4697316"
     CDS             complement(211884..213095)
                     /gene="fadE2"
                     /locus_tag="BCG_0190c"
                     /EC_number="1.3.99.-"
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-CoA dehydrogenase fadE2"
                     /protein_id="YP_976289.1"
                     /db_xref="GI:121636066"
                     /db_xref="GeneID:4697316"
                     /translation="MSAKAIDYRTRLSDFMTEHVFGAEADYDDYRRAAGPADHTAPPI
                     IEELKTKAKDRGLWNLFLSAESGLTNLEYAPLAEMTGWSMEIAPEALNCAAPDTGNME
                     ILHMFGTEQQRAQWLRPLLDGKIRSAFSMTEPAVASSDARNIETTISRDGADYVINGR
                     KWWTSGAADPRCKILIVMGRTNPDAAAHQQQSMVLVPIDTPGVTIVRSTPVFGWQDRH
                     GHCEIDYHNVRVPATNLLGEEGSGFAIAQARLGPGRIHHCMRALGAAERALALMVNRV
                     RNRVAFGRPLAEQGVVQQAIAQSRNEIDQARLLCEKAAWTIDQHGNKEARHLVAMIKA
                     VAPRVACDVIDRAIQVHGAAGVSDDTPLARLYGWHRAMRIFDGPDEVHLRSIARAELS
                     REKSTFAAAVT"
     misc_feature    complement(211923..213095)
                     /gene="fadE2"
                     /locus_tag="BCG_0190c"
                     /note="Acyl-CoA dehydrogenases [Lipid metabolism]; Region:
                     CaiA; COG1960"
                     /db_xref="CDD:224871"
     misc_feature    complement(211920..213089)
                     /gene="fadE2"
                     /locus_tag="BCG_0190c"
                     /note="Acyl-CoA dehydrogenases similar to fadE2; Region:
                     ACAD_FadE2; cd01155"
                     /db_xref="CDD:173844"
     misc_feature    complement(order(212565..212567,212571..212573,
                     212670..212675,212694..212696,212700..212702))
                     /gene="fadE2"
                     /locus_tag="BCG_0190c"
                     /note="FAD binding site [chemical binding]; other site"
                     /db_xref="CDD:173844"
     misc_feature    complement(order(211968..211973,212334..212336,
                     212343..212348,212367..212369,212601..212603))
                     /gene="fadE2"
                     /locus_tag="BCG_0190c"
                     /note="substrate binding site [chemical binding]; other
                     site"
                     /db_xref="CDD:173844"
     misc_feature    complement(211968..211970)
                     /gene="fadE2"
                     /locus_tag="BCG_0190c"
                     /note="catalytic base [active]"
                     /db_xref="CDD:173844"
     gene            213519..214619
                     /gene="pntAa"
                     /locus_tag="BCG_0191"
                     /db_xref="GeneID:4699118"
     CDS             213519..214619
                     /gene="pntAa"
                     /locus_tag="BCG_0191"
                     /EC_number="1.6.1.2"
                     /standard_name="pntAA"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(p) transhydrogenase (subunit alpha) pntAa"
                     /protein_id="YP_976290.1"
                     /db_xref="GI:121636067"
                     /db_xref="GeneID:4699118"
                     /translation="MTDPQTQSTRVGVVAESGPDERRVALVPKAVASLVNRGVAVVVE
                     AGAGERALLPDELYTAVGASIGDAWAADVVVKVAPPTAAEVGRLRGGQTLIGFLAPRN
                     ADNSIGALTQAGVQAFALEAIPRISRAQVMDALSSQANVSGYKAVLLAASESTRFFPM
                     LTTAAGTVKPATVLVLGVGVAGLQALATAKRLGARTTGYDVRPEVADQVRSVGAQWLD
                     LGISASGEGGYARELTDDERAQQQKALEEAISGFDVVITTALVPGRPAPTLVTAAAVE
                     AMKPGSVVVDLAGETGGNCELTEPGRTVVKHDVTIAAPLNLPATMPEHASELYSKNIT
                     ALLDLLIKDGRLAPDFDDEVIAQSCVTRGKDS"
     misc_feature    213546..214613
                     /gene="pntAa"
                     /locus_tag="BCG_0191"
                     /note="NAD/NADP transhydrogenase alpha subunit [Energy
                     production and conversion]; Region: PntA; COG3288"
                     /db_xref="CDD:225826"
     misc_feature    213546..214607
                     /gene="pntAa"
                     /locus_tag="BCG_0191"
                     /note="Rubrum transdehydrogenase NAD-binding and catalytic
                     domains; Region: Rubrum_tdh; cd05304"
                     /db_xref="CDD:240629"
     misc_feature    order(213585..213587,213750..213752,213807..213809,
                     214386..214388,214464..214466,214470..214472)
                     /gene="pntAa"
                     /locus_tag="BCG_0191"
                     /note="ligand binding site [chemical binding]; other site"
                     /db_xref="CDD:240629"
     misc_feature    order(213672..213674,213906..213911,213936..213941,
                     213948..213953,213960..213965,213969..213974,
                     213978..213995,213999..214001,214005..214013,
                     214020..214022,214089..214094,214356..214361,
                     214485..214490,214500..214502,214509..214514)
                     /gene="pntAa"
                     /locus_tag="BCG_0191"
                     /note="homodimer interface [polypeptide binding]; other
                     site"
                     /db_xref="CDD:240629"
     misc_feature    order(213891..213896,213906..213908,213915..213917,
                     213924..213926,214047..214058,214116..214124,
                     214206..214208,214239..214241,214290..214298,
                     214317..214319,214323..214325)
                     /gene="pntAa"
                     /locus_tag="BCG_0191"
                     /note="NAD(P) binding site [chemical binding]; other site"
                     /db_xref="CDD:240629"
     misc_feature    order(213897..213902,213906..213908,213936..213938,
                     214065..214070,214089..214091,214137..214142,
                     214146..214157)
                     /gene="pntAa"
                     /locus_tag="BCG_0191"
                     /note="trimer interface B [polypeptide binding]; other
                     site"
                     /db_xref="CDD:240629"
     misc_feature    order(213996..214010,214017..214019,214026..214028,
                     214095..214097,214101..214103)
                     /gene="pntAa"
                     /locus_tag="BCG_0191"
                     /note="trimer interface A [polypeptide binding]; other
                     site"
                     /db_xref="CDD:240629"
     gene            214620..214952
                     /gene="pntAb"
                     /locus_tag="BCG_0192"
                     /db_xref="GeneID:4696817"
     CDS             214620..214952
                     /gene="pntAb"
                     /locus_tag="BCG_0192"
                     /standard_name="pntAB"
                     /note="Differs from Rv0156 by 1aa, C2Y"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(p) transhydrogenase (subunit alpha) pntAb"
                     /protein_id="YP_976291.1"
                     /db_xref="GI:121636068"
                     /db_xref="GeneID:4696817"
                     /translation="MCNELLENLAILVLSGFVGFAVISKVPNTLHTPLMSGTNAIHGI
                     VVLGALVVFGEIEHPSLVLQVILFVAVVFGTLNVIGGFIVTDRMLGMFKAKKPAVPAK
                     PDRDEALR"
     misc_feature    <214620..>214943
                     /gene="pntAb"
                     /locus_tag="BCG_0192"
                     /note="NAD/NADP transhydrogenase alpha subunit [Energy
                     production and conversion]; Region: PntA; COG3288"
                     /db_xref="CDD:225826"
     misc_feature    214635..214898
                     /gene="pntAb"
                     /locus_tag="BCG_0192"
                     /note="Domain of unknown function (DUF3814); Region:
                     DUF3814; pfam12769"
                     /db_xref="CDD:257285"
     gene            214949..216376
                     /gene="pntB"
                     /locus_tag="BCG_0193"
                     /db_xref="GeneID:4696818"
     CDS             214949..216376
                     /gene="pntB"
                     /locus_tag="BCG_0193"
                     /EC_number="1.6.1.1"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(p) transhydrogenase (subunit beta) pntB"
                     /protein_id="YP_976292.1"
                     /db_xref="GI:121636069"
                     /db_xref="GeneID:4696818"
                     /translation="MNLHYLVEILYIISFSLFIYGLMGLTGPKTAVRGNLIAAAGMTI
                     AVAATLVMIRHTSQWPLIIAGLVVGVVLGVPPARLTKMTAMPQLVAFFNGVGGGTVAL
                     IALSEFIDTTGFSAFQHGESPTVHIVVASLFAAIIGSISFWGSIVAFGKLQEIISGRP
                     IGLGKAQQPINLLLLAVAVAAAVVIGLHAHPGSGGVALWWMIGLLVAAGVLGLMVVLP
                     IGGADMPVVISMLNAMTGLSAAAAGLALNNTAMIVAGMIVGASGSILTNLMAKAMNRS
                     IPAIVAGGFGGGGVAPSGGGDDKHVKATSAADAAIQMAYANQVIVVPGYGLAVAQAQH
                     AVKDLATLLEDRGVPVKYAIHPVAGRMPGHMNVLLAEAEVDYDAMKDMDDINDEFART
                     DVTIVIGANDVTNPAARNETSSPIYGMPILNVDKSRSVIVLKRSMNSGFAGIDNPLFY
                     ADGTTMLFGDAKKSVTEVSEELKAL"
     misc_feature    214961..216364
                     /gene="pntB"
                     /locus_tag="BCG_0193"
                     /note="NAD(P) transhydrogenase beta subunit; Region: PNTB;
                     pfam02233"
                     /db_xref="CDD:251172"
     gene            216682..217326
                     /locus_tag="BCG_0194"
                     /db_xref="GeneID:4696277"
     CDS             216682..217326
                     /locus_tag="BCG_0194"
                     /codon_start=1
                     /transl_table=11
                     /product="TetR family transcriptional regulator"
                     /protein_id="YP_976293.1"
                     /db_xref="GI:121636070"
                     /db_xref="GeneID:4696277"
                     /translation="MPSDTSPNGLSRREELLAVATKLFAARGYHGTRMDDVADVIGLN
                     KATVYHYYASKSLILFDIYRQAAEGTLAAVHDDPSWTAREALYQYTVRLLTAIASNPE
                     RAAVYFQEQPYITEWFTSEQVAEVREKEQQVYEHVHGLIDRGIASGEFYECDSHVVAL
                     GYIGMTLGSYRWLRPSGRRTAKEIAAEFSTALLRGLIRDESIRNQSPLGTRKET"
     misc_feature    216715..217275
                     /locus_tag="BCG_0194"
                     /note="Transcriptional regulator [Transcription]; Region:
                     AcrR; COG1309"
                     /db_xref="CDD:224228"
     misc_feature    216727..216867
                     /locus_tag="BCG_0194"
                     /note="Bacterial regulatory proteins, tetR family; Region:
                     TetR_N; pfam00440"
                     /db_xref="CDD:249860"
     misc_feature    216922..217269
                     /locus_tag="BCG_0194"
                     /note="QacR-like protein, C-terminal region; Region:
                     TetR_C_5; pfam08360"
                     /db_xref="CDD:254757"
     gene            complement(217330..218736)
                     /gene="PE3"
                     /locus_tag="BCG_0195c"
                     /db_xref="GeneID:4696051"
     CDS             complement(217330..218736)
                     /gene="PE3"
                     /locus_tag="BCG_0195c"
                     /note="Differs from Rv0159c by 1aa, T255P"
                     /codon_start=1
                     /transl_table=11
                     /product="PE family protein"
                     /protein_id="YP_976294.1"
                     /db_xref="GI:121636071"
                     /db_xref="GeneID:4696051"
                     /translation="MSYVIAAPEMLATAAADVDGIGSAIRAASASAAGPTTGLLAAAA
                     DEVSSAAAALFSEYARECQEVLKQAAAFHGEFTRALAAAGAAYAQAEASNTAAMSGTA
                     GSSGALGSVGMLSGNPLTALMMGGTGEPILSDRVLAIIDSAYIRPIFGPNNPVAQYTP
                     EQWWPFIGNLSLDQSIAQGVTLLNNGINAELQNGHDVVVFGYSQSAAVATNEIRALMA
                     LPPGQAPDPSRLAFTLIGNINNPNGGVLERYVGLYLTFLDMSFNGATPPDSPYQTYMY
                     TGQYDGYAHNPQYPLNILSDLNAFMGIRWVHNAYPFTAAEVANAVPLPTSPGYTGNTH
                     YYMFLTQDLPLLQPIRAIPFVGTPIAELIQPDLRVLVDLGYGYGYADVPTPASLFAPI
                     NPIAVASALATGTVQGPQAALVSIGLLPQSALPNTYPYLPSANPGLMFNFGQSSVTEL
                     SVLSGALGSVARLIPPIA"
     misc_feature    complement(218503..218736)
                     /gene="PE3"
                     /locus_tag="BCG_0195c"
                     /note="PE family; Region: PE; pfam00934"
                     /db_xref="CDD:250239"
     misc_feature    complement(217609..218280)
                     /gene="PE3"
                     /locus_tag="BCG_0195c"
                     /note="PE-PPE domain; Region: PE-PPE; pfam08237"
                     /db_xref="CDD:254681"
     gene            complement(218828..220336)
                     /gene="PE4"
                     /locus_tag="BCG_0196c"
                     /db_xref="GeneID:4698937"
     CDS             complement(218828..220336)
                     /gene="PE4"
                     /locus_tag="BCG_0196c"
                     /note="Differs from Rv0160c by 2aa, T116A, T211A"
                     /codon_start=1
                     /transl_table=11
                     /product="PE family protein"
                     /protein_id="YP_976295.1"
                     /db_xref="GI:121636072"
                     /db_xref="GeneID:4698937"
                     /translation="MSHLVTAPDMLATAAAHVDEIASTLRAANAAAAGPTCNLLAAAG
                     DEVSAATAALFSAYGREYQAVVKQAAAFHSEFTRTLEAAGNAYAHAEAANAARVSHAL
                     DTINAPIRTLLGRTPLSPNGSSGAGGLPAIAQLAAESPITALIMGGTNNPLPDPEYVT
                     DINKAFIQTLFPGAVSQGLFTPEQFWPVTPDLGNLTFNQSVTEGVALLNTTVNNQLAL
                     DNKVVAFGYSQSATIINNYINSLMAMGSPNPDDISFVMIGSGNNPVGGLLARFPGFYI
                     PFLDVPFNGATPANSPYPTHIYTAQYDGIAHAPQFPLRILSDINAFMGYFYVHNTYPE
                     LMATQVDNAVPLPTSPGYTGNTQYYMFLTQDLPLLQPIRDIPYAGPPIADLFQPQLRV
                     LVDLGYADYGPGGNYADIPTPAGLFSIPNPFAVTYYLIKGSLQAPYGAIVEIGVEAGL
                     IGPEWFPDSYPWVPSINPGLNFYFGQPQVTLLSLMSGGLGNILHLIPPPVFT"
     misc_feature    complement(220082..220336)
                     /gene="PE4"
                     /locus_tag="BCG_0196c"
                     /note="PE family; Region: PE; pfam00934"
                     /db_xref="CDD:250239"
     misc_feature    complement(219140..219820)
                     /gene="PE4"
                     /locus_tag="BCG_0196c"
                     /note="PE-PPE domain; Region: PE-PPE; pfam08237"
                     /db_xref="CDD:254681"
     gene            220504..221853
                     /locus_tag="BCG_0197"
                     /db_xref="GeneID:4696201"
     CDS             220504..221853
                     /locus_tag="BCG_0197"
                     /EC_number="1.-.-.-"
                     /codon_start=1
                     /transl_table=11
                     /product="oxidoreductase"
                     /protein_id="YP_976296.1"
                     /db_xref="GI:121636073"
                     /db_xref="GeneID:4696201"
                     /translation="MLTSLVSAVGSHHVTTDPDVLAGRSVDHTGRYRGRASALVRPGS
                     AEEVAEVLRVCRDAGAYVTVQGGRTSLVAGTVPEHDDVLLSTERLCVVSDVDTVERRI
                     EIGAGVTLAAVQHAASTAGLVFGVDLSARDTATVGGMASTNAGGLRTVRYGNMGEQVV
                     GLDVALPDGTVLRRHSRVRRDNTGYDLPALFVGAEGTLGVITALDLRLHPTPSHRVTA
                     VCGFAELAALVDAGRMFRDVEGIAALELIDGRAAALTREHLGVRPPVEADWLLLVELA
                     ADHDQTDRLADLLGGARMCGEPAVGVDAAAQQRLWRTRESLAEVLGVYGPPLKFDVSL
                     PLSAISGFARDAVALVHRHVPDSPEALPLLFGHIGEGNLHLNVLRCPPDREPALYAKM
                     MGLIAECGGNVSSEHGVGSRKRAYLGMSRQANDVAAMRRVKAALDPTGYLNAAVLFD"
     misc_feature    220513..221847
                     /locus_tag="BCG_0197"
                     /note="FAD/FMN-containing dehydrogenases [Energy
                     production and conversion]; Region: GlcD; COG0277"
                     /db_xref="CDD:223354"
     misc_feature    220609..221022
                     /locus_tag="BCG_0197"
                     /note="FAD binding domain; Region: FAD_binding_4;
                     pfam01565"
                     /db_xref="CDD:250709"
     misc_feature    221134..221832
                     /locus_tag="BCG_0197"
                     /note="FAD linked oxidases, C-terminal domain; Region:
                     FAD-oxidase_C; pfam02913"
                     /db_xref="CDD:251615"
     gene            complement(221881..223032)
                     /gene="adhE1"
                     /locus_tag="BCG_0198c"
                     /db_xref="GeneID:4698436"
     CDS             complement(221881..223032)
                     /gene="adhE1"
                     /locus_tag="BCG_0198c"
                     /EC_number="1.1.1.1"
                     /note="Differs from Rv0162c and Mb0167c by 1aa, R41H"
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-type alcohol dehydrogenase (e subunit)
                     adhE"
                     /protein_id="YP_976297.1"
                     /db_xref="GI:121636074"
                     /db_xref="GeneID:4698436"
                     /translation="MPAVQPWLYSNMPAIRGAVLDQIGVPRPYWRSKPISVVELRLDP
                     PDRGEVLVRIEAAGVCHSDLSVVDGTRVRPVPILLGHEAAGIVEQVGDGVDGVAVGQR
                     VVLVFLPRCGQCAACATDGRTPCEPGSAANKAGTLLGGGIRLSRGGRPVYHHLGVSGF
                     ATHVVVNRASVVPVPHEVPPTVAALLGCAVLTGGGAVLNVGDPQPGQSVAVVGLGGVG
                     MAAVLTALTYTDVRVVAVDQLPEKLSAAKALGAHEIYTPQQATAGGVKAAVVVEAVGH
                     PAALHTAIGLTAPGGRTITVGLPPPDVRISLSPLDFVTEGRSLIGSYLGSAVPSHDIP
                     RFVSLWQSGRLPVESLVTSTIRLDDINEAMDHLADGIAVRQLISFTGDL"
     misc_feature    complement(221896..222990)
                     /gene="adhE1"
                     /locus_tag="BCG_0198c"
                     /note="Zn-dependent alcohol dehydrogenases, class III
                     [Energy production and conversion]; Region: AdhC; COG1062"
                     /db_xref="CDD:223990"
     misc_feature    complement(221902..222990)
                     /gene="adhE1"
                     /locus_tag="BCG_0198c"
                     /note="Medium chain reductase/dehydrogenase
                     (MDR)/zinc-dependent alcohol dehydrogenase-like family;
                     Region: MDR; cl16912"
                     /db_xref="CDD:266485"
     misc_feature    complement(order(222061..222069,222142..222147,
                     222211..222216,222262..222264,222307..222309,
                     222319..222324,222379..222396,222457..222459,
                     222469..222471,222838..222840,222847..222855))
                     /gene="adhE1"
                     /locus_tag="BCG_0198c"
                     /note="NAD(P) binding site [chemical binding]; other site"
                     /db_xref="CDD:176178"
     gene            223014..223469
                     /locus_tag="BCG_0199"
                     /db_xref="GeneID:4697252"
     CDS             223014..223469
                     /locus_tag="BCG_0199"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_976298.1"
                     /db_xref="GI:121636075"
                     /db_xref="GeneID:4697252"
                     /translation="MAALPAPEKLLRSDFPVLWPVGTRWADNDMFGHLNNAVYYQLFD
                     TAINAWINTSTGVDPLAMPVLGIVAESGCRYFSELRFPESLMVGLAVTRLGRSSVTYR
                     LGVFKEPDDAGVITALGHWVHVYVDRTSRRPVPIPEAIRSLLSTACVSG"
     misc_feature    223068..223394
                     /locus_tag="BCG_0199"
                     /note="4-hydroxybenzoyl-CoA thioesterase (4HBT). Catalyzes
                     the final step in the 4-chlorobenzoate degradation pathway
                     in which 4-chlorobenzoate is converted to
                     4-hydroxybenzoate in certain soil-dwelling bacteria. 4HBT
                     forms a homotetramer with four active sites; Region: 4HBT;
                     cd00586"
                     /db_xref="CDD:238329"
     misc_feature    order(223143..223145,223215..223217,223296..223307)
                     /locus_tag="BCG_0199"
                     /note="active site"
                     /db_xref="CDD:238329"
     gene            223523..224008
                     /gene="TB18.5"
                     /locus_tag="BCG_0200"
                     /db_xref="GeneID:4697507"
     CDS             223523..224008
                     /gene="TB18.5"
                     /locus_tag="BCG_0200"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_976299.1"
                     /db_xref="GI:121636076"
                     /db_xref="GeneID:4697507"
                     /translation="MTAISCSPRPRYASRMPVLSKTVEVTADAASIMAIVADIERYPE
                     WNEGVKGAWVLARYDDGRPSQVRLDTAVQGIEGTYIHAVYYPGENQIQTVMQQGELFA
                     KQEQLFSVVATGAASLLTVDMDVQVTMPVPEPMVKMLLNNVLEHLAENLKQRAEQLAA
                     S"
     misc_feature    223568..223987
                     /gene="TB18.5"
                     /locus_tag="BCG_0200"
                     /note="Ligand-binding SRPBCC domain of an uncharacterized
                     subfamily of proteins; Region: SRPBCC_2; cd07819"
                     /db_xref="CDD:176861"
     misc_feature    order(223577..223579,223583..223585,223589..223591,
                     223616..223624,223628..223633,223667..223669,
                     223688..223690,223694..223696,223700..223702,
                     223706..223708,223718..223720,223724..223726,
                     223763..223765,223769..223771,223844..223849,
                     223853..223855,223859..223861,223877..223879,
                     223883..223885,223889..223891,223895..223897,
                     223913..223927,223943..223951,223958..223966,
                     223973..223975)
                     /gene="TB18.5"
                     /locus_tag="BCG_0200"
                     /note="putative hydrophobic ligand binding site [chemical
                     binding]; other site"
                     /db_xref="CDD:176861"
     gene            complement(224022..224837)
                     /locus_tag="BCG_0201c"
                     /db_xref="GeneID:4697561"
     CDS             complement(224022..224837)
                     /locus_tag="BCG_0201c"
                     /note="In Mycobacterium tuberculosis strain H37Rv, Rv0165c
                     exists as a single gene. In Mycobacterium bovis BCG
                     Pasteur, and Mycobacterium bovis, a frameshift due to a 2
                     bp insertion (*-cc) leads to a product with a different
                     COOH terminus"
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="YP_976300.1"
                     /db_xref="GI:121636077"
                     /db_xref="GeneID:4697561"
                     /translation="MIKHDVVWVTLWPERPNNKPPPSPRQVPGNPGPTLKVLASHVNA
                     PLSAKPRSQLPLRRAQLSDEVAGHLRAAIMSGALRSGTFIRLDETAAELGVSVTPVRE
                     ALLKLRGEGMVGLEPHRGHVVLPLTRQDIDDIFWLQATIAQELATSATAHITDVEIDE
                     LDRINNALAGAIGSGDAKTIASIEFAFHRVFNKASRRIKLAWFLLNAARYMPAQVFAA
                     DPRWGADAVNSHRQLIAALRRRDTAAVIEHTVWQFTDGARRLTEALAETEVFG"
     misc_feature    complement(224034..224705)
                     /locus_tag="BCG_0201c"
                     /note="Transcriptional regulators [Transcription]; Region:
                     GntR; COG1802"
                     /db_xref="CDD:224715"
     misc_feature    complement(224469..224657)
                     /locus_tag="BCG_0201c"
                     /note="Winged helix-turn-helix (WHTH) DNA-binding domain
                     of the GntR family of transcriptional regulators; Region:
                     WHTH_GntR; cl17414"
                     /db_xref="CDD:266669"
     misc_feature    complement(order(224475..224486,224490..224495,
                     224523..224525,224532..224537,224541..224555,
                     224577..224579,224652..224654))
                     /locus_tag="BCG_0201c"
                     /note="DNA-binding site [nucleotide binding]; DNA binding
                     site"
                     /db_xref="CDD:153418"
     misc_feature    complement(224103..224441)
                     /locus_tag="BCG_0201c"
                     /note="FCD domain; Region: FCD; pfam07729"
                     /db_xref="CDD:254389"
     gene            224892..226556
                     /gene="fadD5"
                     /locus_tag="BCG_0203"
                     /db_xref="GeneID:4697652"
     CDS             224892..226556
                     /gene="fadD5"
                     /locus_tag="BCG_0203"
                     /EC_number="2.3.1.86"
                     /note="activates fatty acids by binding to coenzyme A"
                     /codon_start=1
                     /transl_table=11
                     /product="long-chain-fatty-acid--CoA ligase"
                     /protein_id="YP_976301.1"
                     /db_xref="GI:121636078"
                     /db_xref="GeneID:4697652"
                     /translation="MTAQLASHLTRALTLAQQQPYLARRQNWVNQLERHAMMQPDAPA
                     LRFVGNTMTWADLRRRVAALAGALSGRGVGFGDRVMILMLNRTEFVESVLAANMIGAI
                     AVPLNFRLTPTEIAVLVEDCAAHVMLTEAALAPVAIGVRNIQPLLSVIVVAGGSSQDS
                     VFGYEDLLNEAGDVHEPVDIPNDSPALIMYTAGTTGRPKGAVLTHANLTGQAMTALYT
                     SGANINSDVGFVGVPLFHIAGIGNMLTGLLLGLPTVIYPLGAFDPGQLLDVLEAEKVT
                     GIFLVPAQWQAVCTEQQARPRDLRLRVLSWGAAPAPDALLRQMSATFPETQILAAFGQ
                     TEMSPVTCMLLGEDAIAKRGSVGRVIPTVAARVVDQNMNDVPVGEVGEIVYRAPTLMS
                     CYWNNPEATAEAFAGGWFHSGDLVRMDSDGYVWVVDRKKDMIISGGENIYCAELENVL
                     ASHPDIAEVAVIGRADEKWGEVPIAVAAVTNDDLRIEDLGEFLTDRLARYKHPKALEI
                     VDALPRNPAGKVLKTELRLRYGACVNVERRSASAGFTERRENRQKL"
     misc_feature    224919..226538
                     /gene="fadD5"
                     /locus_tag="BCG_0203"
                     /note="long-chain-fatty-acid--CoA ligase; Validated;
                     Region: PRK07786"
                     /db_xref="CDD:169098"
     misc_feature    225438..226469
                     /gene="fadD5"
                     /locus_tag="BCG_0203"
                     /note="Bacterial Bile acid CoA ligases and similar
                     proteins; Region: BACL_like; cd05929"
                     /db_xref="CDD:213295"
     misc_feature    order(225453..225455,225462..225479,225483..225488)
                     /gene="fadD5"
                     /locus_tag="BCG_0203"
                     /note="acyl-activating enzyme (AAE) consensus motif; other
                     site"
                     /db_xref="CDD:213295"
     misc_feature    order(225462..225464,225810..225815,225879..225896,
                     226131..226133,226167..226169,226176..226178,
                     226209..226211,226446..226448)
                     /gene="fadD5"
                     /locus_tag="BCG_0203"
                     /note="putative AMP binding site [chemical binding]; other
                     site"
                     /db_xref="CDD:213295"
     misc_feature    order(225462..225464,225585..225590,225732..225734,
                     225738..225743,225750..225752,225810..225815,
                     225879..225896,226131..226133,226167..226169,
                     226176..226178,226200..226211,226389..226391)
                     /gene="fadD5"
                     /locus_tag="BCG_0203"
                     /note="putative active site [active]"
                     /db_xref="CDD:213295"
     misc_feature    order(225585..225587,225738..225743,225750..225752,
                     225810..225812,226200..226208,226371..226373,
                     226389..226391)
                     /gene="fadD5"
                     /locus_tag="BCG_0203"
                     /note="putative CoA binding site [chemical binding]; other
                     site"
                     /db_xref="CDD:213295"
     gene            226760..227557
                     /gene="yrbE1A"
                     /locus_tag="BCG_0204"
                     /db_xref="GeneID:4696272"
     CDS             226760..227557
                     /gene="yrbE1A"
                     /locus_tag="BCG_0204"
                     /codon_start=1
                     /transl_table=11
                     /product="integral membrane protein YrbE1a"
                     /protein_id="YP_976302.1"
                     /db_xref="GI:121636079"
                     /db_xref="GeneID:4696272"
                     /translation="MTTSTTLGGYVRDQLQTPLTLVGGFFRMCVLTGKALFRWPFQWR
                     EFILQCWFIMRVGFLPTIMVSIPLTVLLIFTLNILLAQFGAADISGSGAAIGAVTQLG
                     PLTTVLVVAGAGSTAICADLGARTIREEIDAMEVLGIDPIHRLVVPRVLASMLVATLL
                     NGLVITVGLVGGFLFGVYLQNVSGGAYLATLTLITGLPEVVIATIKAATFGLIAGLVG
                     CYRGLTVRGGSKGLGTAVNETVVLCVIALFAVNVILTTIGVRFGTGR"
     misc_feature    226784..227548
                     /gene="yrbE1A"
                     /locus_tag="BCG_0204"
                     /note="ABC-type transport system involved in resistance to
                     organic solvents, permease component [Secondary
                     metabolites biosynthesis, transport, and catabolism];
                     Region: Ttg2B; COG0767"
                     /db_xref="CDD:223838"
     gene            227559..228428
                     /gene="yrbE1B"
                     /locus_tag="BCG_0205"
                     /db_xref="GeneID:4697801"
     CDS             227559..228428
                     /gene="yrbE1B"
                     /locus_tag="BCG_0205"
                     /codon_start=1
                     /transl_table=11
                     /product="integral membrane protein YrbE1b"
                     /protein_id="YP_976303.1"
                     /db_xref="GI:121636080"
                     /db_xref="GeneID:4697801"
                     /translation="MSTAAVLRARFPRAVANLRQYGGAAARGLDEAGQLTWFALTSIG
                     QIAHALRYYRKETLRLIAQIGMGTGAMAVVGGTVAIVGFVTLSGSSLVAIQGFASLGN
                     IGVEAFTGFFAALINVRIAGPVVTGVALAATVGAGATAELGAMRISEEIDALEVMGIK
                     SISFLASTRIMAGLVVIIPLYALAMIMSFLSPQITTTVLYGQSNGTYEHYFQTFLRPD
                     DVFWSFLEALIITAIVMVSHCYYGYAAGGGPVGVGEAVGRSMRFSLVSVQVVVLFAAL
                     ALYGVDPNFNLTV"
     misc_feature    227580..228407
                     /gene="yrbE1B"
                     /locus_tag="BCG_0205"
                     /note="ABC-type transport system involved in resistance to
                     organic solvents, permease component [Secondary
                     metabolites biosynthesis, transport, and catabolism];
                     Region: Ttg2B; COG0767"
                     /db_xref="CDD:223838"
     gene            228433..229797
                     /gene="mce1A"
                     /locus_tag="BCG_0206"
                     /db_xref="GeneID:4697802"
     CDS             228433..229797
                     /gene="mce1A"
                     /locus_tag="BCG_0206"
                     /standard_name="mce1"
                     /note="Differs from Rv0169 by 2aa, A313S, S359P;
                     Differs from Rv0169 by 2aa, A313S, S359P"
                     /codon_start=1
                     /transl_table=11
                     /product="MCE-family protein mce1A"
                     /protein_id="YP_976304.1"
                     /db_xref="GI:121636081"
                     /db_xref="GeneID:4697802"
                     /translation="MTTPGKLNKARVPPYKTAGLGLVLVFALVVALVYLQFRGEFTPK
                     TQLTMLSARAGLVMDPGSKVTYNGVEIGRVDTISEVTRDGESAAKFILDVDPRYIHLI
                     PANVNADIKATTVFGGKYVSLTTPKNPTKRRITPKDVIDVRSVTTEINTLFQTLTSIA
                     EKVDPVKLNLTLSAAAEALTGLGDKFGESIVNANTVLDDLNSRMPQSRHDIQQLAALG
                     DVYADAAPDLFDFLDSSVTTARTINAQQAELDSALLAAAGFGNTTADVFDRGGPYLQR
                     GVADLVPTATLLDTYSPELFCTIRNFYDADPLAKAAAGGGNGYSLRTNSEILSGIGIS
                     LLSPLALATNGAAIGIGLVAGLIASPLAVAANLAGALPGIVGGAPNPYTYPENLPRVN
                     ARGGPGGAPGCWQPITRDLWPAPYLVMDTGASLAPYNHMEVGSPYAVEYVWGRQVGDN
                     TINP"
     misc_feature    228475..229353
                     /gene="mce1A"
                     /locus_tag="BCG_0206"
                     /note="virulence factor Mce family protein; Region:
                     Mtu_fam_mce; TIGR00996"
                     /db_xref="CDD:233227"
     misc_feature    228559..228810
                     /gene="mce1A"
                     /locus_tag="BCG_0206"
                     /note="mce related protein; Region: MCE; pfam02470"
                     /db_xref="CDD:251316"
     misc_feature    228892..229794
                     /gene="mce1A"
                     /locus_tag="BCG_0206"
                     /note="Protein of unknown function (DUF3407); Region:
                     DUF3407; pfam11887"
                     /db_xref="CDD:256700"
     gene            229794..230834
                     /gene="mce1B"
                     /locus_tag="BCG_0207"
                     /db_xref="GeneID:4695351"
     CDS             229794..230834
                     /gene="mce1B"
                     /locus_tag="BCG_0207"
                     /standard_name="mceD"
                     /note="Differs from Rv0170 by 1aa, T179I"
                     /codon_start=1
                     /transl_table=11
                     /product="MCE-family protein mce1B"
                     /protein_id="YP_976305.1"
                     /db_xref="GI:121636082"
                     /db_xref="GeneID:4695351"
                     /translation="MKITGTVVKLGIVSVVLLFFTVMIIVIFGQMRFDRTNGYTAEFS
                     NVSGLRQGQFVRASGVEIGKVKALHLVDGGRRVRVEFNIDRSVPLYQSTTAQIRYSDL
                     IGNRYVELKRGEGKGANDLLPPGGLIPLSRTSPALDLDALIGGFKPVFRALDPAKVNN
                     IANALITVFQGQGGTINDTLDQTAQLTSQIAERDQAIGEVVKNLNIVLDTTVKHRKEF
                     DETVNNLENLITGLRNHSDQLAGGLAHISNGAGTVADLLAENRTLVRKAVSYLDAIQQ
                     PVIDQRVELDDLLHKTPTALTALGRANGTYGDFQNFYLCDLQIKWNGFQAGGPVRTVK
                     LFSQPTGRCTPQ"
     misc_feature    229809..230831
                     /gene="mce1B"
                     /locus_tag="BCG_0207"
                     /note="ABC-type transport system involved in resistance to
                     organic solvents, periplasmic component [Secondary
                     metabolites biosynthesis, transport, and catabolism];
                     Region: Ttg2C; COG1463"
                     /db_xref="CDD:224380"
     misc_feature    229896..230132
                     /gene="mce1B"
                     /locus_tag="BCG_0207"
                     /note="mce related protein; Region: MCE; pfam02470"
                     /db_xref="CDD:251316"
     misc_feature    230235..>230588
                     /gene="mce1B"
                     /locus_tag="BCG_0207"
                     /note="Protein of unknown function (DUF3407); Region:
                     DUF3407; pfam11887"
                     /db_xref="CDD:256700"
     gene            230831..232378
                     /gene="mce1C"
                     /locus_tag="BCG_0208"
                     /db_xref="GeneID:4697196"
     CDS             230831..232378
                     /gene="mce1C"
                     /locus_tag="BCG_0208"
                     /note="Differs from Rv0171 by 1aa, D212E"
                     /codon_start=1
                     /transl_table=11
                     /product="MCE-family protein mce1C"
                     /protein_id="YP_976306.1"
                     /db_xref="GI:121636083"
                     /db_xref="GeneID:4697196"
                     /translation="MRTLEPPNRMRIGLMGIVVALLVVAVGQSFTSVPMLFAKPSYYG
                     QFTDSGGLHKGDRVRIAGLGVGTVEGLKIDGDHIVVKFSIGTNTIGTESRLAIRTDTI
                     LGRKVLEIEPRGAQALPPGGVLPVGQSTTPYQIYDAFFDVTKAASGWDIETVKRSLNV
                     LSETVDQTYPHLSAALDGVAKFSDTIGKRDEQITHLLAQANQVASILGDRSDQVDRLL
                     VNAKTLIAAFNERGRAVDALLGNISAFSAQVQNLINDNPNLNHVLEQLRILTDLLVDR
                     KEDLAETLTILGRFSASFGETFASGPYFKVLLANLVPGQILQPFVDAAFKKRGISPED
                     FWRSAGLPAYRWPDPNGTRFPNGAPPPPPPVLEGTPEHPGPAVPPGSPCSYTPPADGL
                     PRPWDPLPCANLTQGPFGGPDFPAPLDVATSPPNPDGPPPAPGLPIAGRPGEVPPNVP
                     GTPVPIPQEAPPGARTLPLGPAPGPAPPPAAPGPPAPPGPGPQLPAPFINPGGTGGSG
                     VTGGSEN"
     misc_feature    230861..231709
                     /gene="mce1C"
                     /locus_tag="BCG_0208"
                     /note="virulence factor Mce family protein; Region:
                     Mtu_fam_mce; TIGR00996"
                     /db_xref="CDD:233227"
     misc_feature    230942..231169
                     /gene="mce1C"
                     /locus_tag="BCG_0208"
                     /note="mce related protein; Region: MCE; pfam02470"
                     /db_xref="CDD:251316"
     gene            232375..233967
                     /gene="mce1D"
                     /locus_tag="BCG_0209"
                     /db_xref="GeneID:4697197"
     CDS             232375..233967
                     /gene="mce1D"
                     /locus_tag="BCG_0209"
                     /codon_start=1
                     /transl_table=11
                     /product="MCE-family protein mce1D"
                     /protein_id="YP_976307.1"
                     /db_xref="GI:121636084"
                     /db_xref="GeneID:4697197"
                     /translation="MSTIFDIRNLRLPQLSRASVVIGSLVVVLALAAGIVGVRLYQKL
                     TNNTVVAYFTQANALYVGDKVQIMGLPVGSIDKIEPAGDKMKVTFHYQNKYKVPANAS
                     AVILNPTLVASRNIQLEPPYRGGPVLADNAVIPVERTQVPTEWDELRDSVSHIIDELG
                     PTPEQPKGPFGEVIEAFADGLAGKGKQINTTLNSLSQALNALNEGRGDFFAVVRSLAL
                     FVNALHQDDQQFVALNKNLAEFTDRLTHSDADLSNAIQQFDSLLAVARPFFAKNREVL
                     THDVNNLATVTTTLLQPDPLDGLETVLHIFPTLAANINQLYHPTHGGVVSLSAFTNFA
                     NPMEFICSSIQAGSRLGYQESAELCAQYLAPVLDAIKFNYFPFGLNVASTASTLPKEI
                     AYSEPRLQPPNGYKDTTVPGIWVPDTPLSHRNTQPGWVVAPGMQGVQVGPITQGLLTP
                     ESLAELMGGPDIAPPSSGLQTPPGPPNAYDEYPVLPPIGLQAPQVPIPPPPPGPDVIP
                     GPVPPTPAPVGAPLPAEAGGGQ"
     misc_feature    232432..233310
                     /gene="mce1D"
                     /locus_tag="BCG_0209"
                     /note="virulence factor Mce family protein; Region:
                     Mtu_fam_mce; TIGR00996"
                     /db_xref="CDD:233227"
     misc_feature    232510..232737
                     /gene="mce1D"
                     /locus_tag="BCG_0209"
                     /note="mce related protein; Region: MCE; pfam02470"
                     /db_xref="CDD:251316"
     gene            233964..235136
                     /gene="lprK"
                     /locus_tag="BCG_0210"
                     /db_xref="GeneID:4697198"
     CDS             233964..235136
                     /gene="lprK"
                     /locus_tag="BCG_0210"
                     /standard_name="mce1E"
                     /codon_start=1
                     /transl_table=11
                     /product="mce family lipoprotein LprK"
                     /protein_id="YP_976308.1"
                     /db_xref="GI:121636085"
                     /db_xref="GeneID:4697198"
                     /translation="MMSVLARMRVMRHRAWQGLVLLVLALLLSSCGWRGISNVAIPGG
                     PGTGPGSYTIYVQMPDTLAINGNSRVMVADVWVGSIRAIKLKNWVATLTLSLKKDVTL
                     PKNATAKIGQTSLLGSQHVELAAPPDPSPVPLKDGDTIPLKRSSAYPTTEQTLASIAT
                     LLRGGGLVNLEGIQQEINAIVTGRADQIRAFLGKLDTFTDELNQQRDDITRAIDSTNR
                     LLAYVGGRSEVLNRVLTDLPPLIKHFADKQELLINASDAVGRLSQSADQYLSAARGDL
                     HQDLQALQCPLKELRRAAPYLVGALKLILTQPFDVDTVPQLVRGDYMNLSLTLDLTYS
                     AIDNAFLTGTGFSGALRALEQSFGRDPETMIPDIRYTPNPNDAPGGPLVERGNRQC"
     misc_feature    234051..234890
                     /gene="lprK"
                     /locus_tag="BCG_0210"
                     /note="virulence factor Mce family protein; Region:
                     Mtu_fam_mce; TIGR00996"
                     /db_xref="CDD:233227"
     misc_feature    234114..234341
                     /gene="lprK"
                     /locus_tag="BCG_0210"
                     /note="mce related protein; Region: MCE; pfam02470"
                     /db_xref="CDD:251316"
     gene            235130..236677
                     /gene="mce1F"
                     /locus_tag="BCG_0211"
                     /db_xref="GeneID:4698588"
     CDS             235130..236677
                     /gene="mce1F"
                     /locus_tag="BCG_0211"
                     /note="Differs from Rv0174 by 1aa, P370L"
                     /codon_start=1
                     /transl_table=11
                     /product="MCE-family protein mce1F"
                     /protein_id="YP_976309.1"
                     /db_xref="GI:121636086"
                     /db_xref="GeneID:4698588"
                     /translation="MLTRFIRRQLILFAIVSVVAIVVLGWYYLRIPSLVGIGQYTLKA
                     DLPASGGLYPTANVTYRGITIGKVTAVEPTDQGARVTMSIASNYKIPVDASANVHSVS
                     AVGEQYIDLVSTGAPGKYFSSGQTITKGTVPSEIGPALDNSNRGLAALPTEKIGLLLD
                     ETAQAVGGLGPALQRLVDSTQAIVGDFKTNIGDVNDIIENSGPILDSQVNTGDQIERW
                     ARKLNNLAAQTATRDQNVRSILSQAAPTADEVNAVFSGVRDSLPQTLANLEVVFDMLK
                     RYHAGVEQLLVFLPQGAAIAQTVLTPTPGAAQLPLAPAINYPPPCLTGFLPASEWRSP
                     ADTSPRPLPSGTYCKIPQDAQLQVRGARNIPCVDVPGKRAATPKECRSKDPYVPLGTN
                     PWFGDPNQILTCPAPGARCDQPVKPGLVIPAPSINTGLNPAPADQVQGTPPPVSDPLQ
                     RPGSGTVQCNGQQPNPCVYTPTSGPSAVYSPASGELVGPDGVKYAVANSSTTGDDGWK
                     EMLAPAS"
     misc_feature    235154..236014
                     /gene="mce1F"
                     /locus_tag="BCG_0211"
                     /note="virulence factor Mce family protein; Region:
                     Mtu_fam_mce; TIGR00996"
                     /db_xref="CDD:233227"
     misc_feature    235247..235465
                     /gene="mce1F"
                     /locus_tag="BCG_0211"
                     /note="mce related protein; Region: MCE; pfam02470"
                     /db_xref="CDD:251316"
     gene            236713..237354
                     /locus_tag="BCG_0212"
                     /db_xref="GeneID:4697199"
     CDS             236713..237354
                     /locus_tag="BCG_0212"
                     /codon_start=1
                     /transl_table=11
                     /product="mce associated membrane protein"
                     /protein_id="YP_976310.1"
                     /db_xref="GI:121636087"
                     /db_xref="GeneID:4697199"
                     /translation="MKAADSAESDAGADQTGPQVKAADSAESDAGELGEDACPEQALV
                     ERRPSRLRRGWLVGIAATLLALAGGLGAAGYFALRSHQESQSIAREDLAAIEAAKDCV
                     AATQAPDAGAMSASMQKIIECGTGDFGAQASLYTSMLVEAYQAASVHVQVTDMRAAVE
                     RNNNDGSVDVLVALRVKVSNTDSDAHEVGYRLRVRMALDEGRYKIAKLDQVTK"
     gene            237351..238319
                     /locus_tag="BCG_0213"
                     /db_xref="GeneID:4697872"
     CDS             237351..238319
                     /locus_tag="BCG_0213"
                     /note="Differs from Mb0182 by 1aa, S285N, and from Rv0176
                     by 3aa, S285N, S290Q, A291S"
                     /codon_start=1
                     /transl_table=11
                     /product="mce associated transmembrane protein"
                     /protein_id="YP_976311.1"
                     /db_xref="GI:121636088"
                     /db_xref="GeneID:4697872"
                     /translation="MTVVVEKTPTTLPQATPNGAAPWHVRAGAFAIDVLPGLAVAATM
                     ALTALTVPPGSAWRWLCACLLGLTILLLAVNRLLLPTITGWSLGRALTGIRVVRRDGS
                     AIGPWRLLVRDLAHLVDTLSLFVGWLWPLWDSRRRTFADLLLRTEVRRVEPVQRPAVI
                     RRLTAAVALAAAGACASATAVGAAVVYVNEWQTDHTRAQLATRGPKLVVDVLSYDPET
                     VQRDFERARSLATDRYRPQLSIQQDSVRESGPVRNQYWVTDSAVLSATPAQATMLLFM
                     QGERGTPPSQRYISATVRAIFQKSRGQWRLDDLAVVMKPRQPTGEK"
     misc_feature    237411..237785
                     /locus_tag="BCG_0213"
                     /note="RDD family; Region: RDD; pfam06271"
                     /db_xref="CDD:253650"
     gene            238316..238870
                     /locus_tag="BCG_0214"
                     /db_xref="GeneID:4697011"
     CDS             238316..238870
                     /locus_tag="BCG_0214"
                     /codon_start=1
                     /transl_table=11
                     /product="mce associated protein"
                     /protein_id="YP_976312.1"
                     /db_xref="GI:121636089"
                     /db_xref="GeneID:4697011"
                     /translation="MSPRRKFEPGEGALLAPQSIEPSRRWGLPLALTASAVVMAAAIS
                     ACALMRISHESHQRAAHKDIVMLSDVRSFMTMFTSPDPFHANEYAERVLSHATGDFAK
                     QYHERANDILIRISGVEPTTGTVLDAGVQRWNEDGSANVLVVTQITSKSADGKRVVSN
                     ANRWLVTAKQEGNEWKISSLLPVI"
     gene            238837..239571
                     /locus_tag="BCG_0215"
                     /db_xref="GeneID:4696892"
     CDS             238837..239571
                     /locus_tag="BCG_0215"
                     /codon_start=1
                     /transl_table=11
                     /product="MCE associated membrane protein"
                     /protein_id="YP_976313.1"
                     /db_xref="GI:121636090"
                     /db_xref="GeneID:4696892"
                     /translation="MEDQQSASGDLTQKSVANGESTDTASAATEGHRGEIDAAGEPDE
                     RGAAVADSQADEDDSAATAARGGKTRARRSRGRRLAITVGVAAALFVGSAAFAGATVE
                     PYLSERAVVATKLMVARTAANAITTLWTYTPENMDTLADRAANYLSGDFAAQYRRFVD
                     QIAAANKQAKITNDTEVTGAAVESLSGRDAVAIVYTNTTTTSPVTKNIPALKYLSYRL
                     FMKRYDARWLVTRMTTITSLDLTPQV"
     misc_feature    <239158..239391
                     /locus_tag="BCG_0215"
                     /note="indolepyruvate ferredoxin oxidoreductase;
                     Validated; Region: PRK09193"
                     /db_xref="CDD:169705"
     gene            complement(239602..240711)
                     /gene="lprO"
                     /locus_tag="BCG_0216c"
                     /db_xref="GeneID:4696358"
     CDS             complement(239602..240711)
                     /gene="lprO"
                     /locus_tag="BCG_0216c"
                     /note="Differs from Rv0179c by 1aa, H124R"
                     /codon_start=1
                     /transl_table=11
                     /product="lipoprotein lprO"
                     /protein_id="YP_976314.1"
                     /db_xref="GI:121636091"
                     /db_xref="GeneID:4696358"
                     /translation="MWIRAERVAVLTPTASLRRLTACYAALAVCAALACTTGQPAARA
                     ADGREMLAQAIATTRGSYLVYNFGGGHPMPLLNAGGHWYEMNNGGHLMIIKNASQRLS
                     PHLLVDTHTGDQARCEHNPGAHTGEGLWQASEIYPPLKAWQRMGRPTIAVNANFFDVR
                     GQKGGSWRSTGCSSPLGAYVDNTRGQGRANQAVTGTVAYAGKQGLSGGNELWSSLTTM
                     ILPVGGAPYVLRPKSRQDYDLATPVIEDLLNKNARFVAVAGIGLLSPGNTGQLHDGGP
                     SAARTALAYAKQKDEMYIFQGGNYTPDNIQDLFRGLGSDTAILLDGGGSSAIVLRRDT
                     GGMWAGAGSPKGSCDTRQVLCDSHERALPSWLAFN"
     misc_feature    complement(239716..>239892)
                     /gene="lprO"
                     /locus_tag="BCG_0216c"
                     /note="Predicted periplasmic protein (DUF2233); Region:
                     DUF2233; pfam09992"
                     /db_xref="CDD:255681"
     gene            complement(240791..242149)
                     /locus_tag="BCG_0217c"
                     /db_xref="GeneID:4698591"
     CDS             complement(240791..242149)
                     /locus_tag="BCG_0217c"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_976315.1"
                     /db_xref="GI:121636092"
                     /db_xref="GeneID:4698591"
                     /translation="MSQAQPRPAAPNPKRNVKAIRTVRFWMAPIATTLALMSALAALY
                     LGGILNPMTNLRHFPIALVNEDAGPAGQQIVDGLVSGLDKNKFDIRVVSPDEARRLLD
                     TAAVYGSALIPPTFSSQLRDFGASAVTPTRTDRPAITISTNPRAGTLAASIAGQTLTR
                     ALTVVNGKVGERLTAEVAAQTGGVALAGAAAAGLASPIDVKSTAYNPLPNGTGNGLSA
                     FYYALLLLLAGFTGSIVVSTLVDSMLGYVPAEFGPVYRFAEQVNISRFRTLLVKWAVM
                     VVLALLTSGVYLAIAHGLGMPIPLGWQVWLYGVFAIIAVGVTSSSLIAVLGSMGLLVS
                     MLIFVILGLPSAGATVPLEAVPAFFRWLAQFEPMHQVFLGVRSLLYLNGNADAGLSQA
                     LTMTSIGLIIGLLLGGFITHLYDRSSFHRIPGAVEMAIAVEHQAQYQARQSARESSSE
                     QP"
     misc_feature    complement(<240800..242119)
                     /locus_tag="BCG_0217c"
                     /note="Predicted membrane protein [Function unknown];
                     Region: COG1511"
                     /db_xref="CDD:224428"
     misc_feature    complement(241637..>242002)
                     /locus_tag="BCG_0217c"
                     /note="YhgE/Pip N-terminal domain; Region: pip_yhgE_Nterm;
                     cl19580"
                     /db_xref="CDD:267933"
     misc_feature    complement(240965..241564)
                     /locus_tag="BCG_0217c"
                     /note="ABC-2 type transporter; Region: ABC2_membrane;
                     cl21474"
                     /db_xref="CDD:271894"
     gene            complement(242176..242910)
                     /locus_tag="BCG_0218c"
                     /db_xref="GeneID:4697013"
     CDS             complement(242176..242910)
                     /locus_tag="BCG_0218c"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_976316.1"
                     /db_xref="GI:121636093"
                     /db_xref="GeneID:4697013"
                     /translation="MTATVEIRRAADRAVTTTSWLKSRHSFSFGDHYDPDNTHHGLLL
                     VNNDDQMEPASGFDPHPHRDMEIVTWVLRGALRHQDSAGNSGVIYPGLAQRMSAGTGI
                     LHSEMNDSATEPVHFVQMWVIPDATGITASYQQQEIDDELLRAGLVTIASGIPGQDAA
                     LTLHNSSASLHGARLRPGATVSLPCAPFLHLFVAYGRLTLEGGGELADGDAVRFTDAD
                     ARGLTANEPSEVLIWEMHAKLGDSAT"
     misc_feature    complement(242179..242895)
                     /locus_tag="BCG_0218c"
                     /note="Pirin-related protein [General function prediction
                     only]; Region: COG1741"
                     /db_xref="CDD:224655"
     misc_feature    complement(242545..242874)
                     /locus_tag="BCG_0218c"
                     /note="Pirin; Region: Pirin; pfam02678"
                     /db_xref="CDD:251469"
     gene            complement(242927..244039)
                     /gene="sigG"
                     /locus_tag="BCG_0219c"
                     /db_xref="GeneID:4695936"
     CDS             complement(242927..244039)
                     /gene="sigG"
                     /locus_tag="BCG_0219c"
                     /EC_number="2.7.7.6"
                     /note="DNA-dependent RNA polymerase catalyzes the
                     transcription of DNA into RNA using the four
                     ribonucleoside triphosphates as substrates"
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase factor sigma-70"
                     /protein_id="YP_976317.1"
                     /db_xref="GI:121636094"
                     /db_xref="GeneID:4695936"
                     /translation="MRTSPMPAKFRSVRVVVITGSVTAAPVRVSETLRRLIDVSVLAE
                     NSGREPADERRGDFSAHTEPYRRELLAHCYRMTGSLHDAEDLVQETLLRAWKAYEGFA
                     GKSSLRTWLHRIATNTCLTALEGRRRRPLPTGLGRPSADPSGELVERREVSWLEPLPD
                     VTDDPADPSTIVGNRESVRLAFVAALQHLSPRQRAVLLLRDVLQWKSAEVADAIGTST
                     VAVNSLLQRARSQLQTVRPSAADRLSAPDSPEAQDLLARYIAAFEAYDIDRLVELFTA
                     EAIWEMPPYTGWYQGAQAIVTLIHQQCPAYSPGDMRLISLIANGQPAAAMYMRAGDVH
                     LPFQLHVLDMAADRVSHVVAFLDTTLFPKFGLPDSL"
     misc_feature    complement(242930..243895)
                     /gene="sigG"
                     /locus_tag="BCG_0219c"
                     /note="RNA polymerase factor sigma-70; Validated; Region:
                     PRK08241"
                     /db_xref="CDD:236196"
     misc_feature    complement(243653..243853)
                     /gene="sigG"
                     /locus_tag="BCG_0219c"
                     /note="Sigma-70 region 2; Region: Sigma70_r2; pfam04542"
                     /db_xref="CDD:252661"
     misc_feature    complement(243341..243487)
                     /gene="sigG"
                     /locus_tag="BCG_0219c"
                     /note="Sigma70, region (SR) 4 refers to the most
                     C-terminal of four conserved domains found in Escherichia
                     coli (Ec) sigma70, the main housekeeping sigma, and
                     related sigma-factors (SFs). A SF is a dissociable subunit
                     of RNA polymerase, it directs bacterial or...; Region:
                     Sigma70_r4; cd06171"
                     /db_xref="CDD:100119"
     misc_feature    complement(order(243353..243355,243359..243364,
                     243368..243376,243380..243385,243389..243391,
                     243419..243424,243440..243442,243470..243472))
                     /gene="sigG"
                     /locus_tag="BCG_0219c"
                     /note="DNA binding residues [nucleotide binding]"
                     /db_xref="CDD:100119"
     misc_feature    complement(<243059..243277)
                     /gene="sigG"
                     /locus_tag="BCG_0219c"
                     /note="SnoaL-like domain; Region: SnoaL_2; pfam12680"
                     /db_xref="CDD:257217"
     gene            243987..244826
                     /locus_tag="BCG_0220"
                     /db_xref="GeneID:4695354"
     CDS             243987..244826
                     /locus_tag="BCG_0220"
                     /EC_number="3.1.-.-"
                     /codon_start=1
                     /transl_table=11
                     /product="lysophospholipase"
                     /protein_id="YP_976318.1"
                     /db_xref="GI:121636095"
                     /db_xref="GeneID:4695354"
                     /translation="MTTTRTERNFAGIGDVRIVYDVWTPDTAPQAVVVLAHGLGEHAR
                     RYDHVAQRLGAAGLVTYALDHRGHGRSGGKRVLVRDISEYTADFDTLVGIATREYPGC
                     KRIVLGHSMGGGIVFAYGVERPDNYDLMVLSAPAVAAQDLVSPVVAVAAKLLGVVVPG
                     LPVQELDFTAISRDPEVVQAYNTDPLVHHGRVPAGIGRALLQVGETMPRRAPALTAPL
                     LVLHGTDDRLIPIEGSRRLVECVGSADVQLKEYPGLYHEVFNEPERNQVLDDVVAWLT
                     ERL"
     misc_feature    243987..244823
                     /locus_tag="BCG_0220"
                     /note="Lysophospholipase [Lipid metabolism]; Region: PldB;
                     COG2267"
                     /db_xref="CDD:225176"
     misc_feature    244029..244262
                     /locus_tag="BCG_0220"
                     /note="Putative lysophospholipase; Region: Hydrolase_4;
                     pfam12146"
                     /db_xref="CDD:256874"
     misc_feature    <244218..>244472
                     /locus_tag="BCG_0220"
                     /note="Esterases and lipases (includes fungal lipases,
                     cholinesterases, etc.)  These enzymes act on carboxylic
                     esters (EC: 3.1.1.-). The catalytic apparatus involves
                     three residues (catalytic triad): a serine, a glutamate or
                     aspartate and a histidine.These...; Region:
                     Esterase_lipase; cl21494"
                     /db_xref="CDD:271914"
     misc_feature    <244635..244823
                     /locus_tag="BCG_0220"
                     /note="Esterases and lipases (includes fungal lipases,
                     cholinesterases, etc.)  These enzymes act on carboxylic
                     esters (EC: 3.1.1.-). The catalytic apparatus involves
                     three residues (catalytic triad): a serine, a glutamate or
                     aspartate and a histidine.These...; Region:
                     Esterase_lipase; cl21494"
                     /db_xref="CDD:271914"
     gene            244868..245617
                     /locus_tag="BCG_0221"
                     /db_xref="GeneID:4697419"
     CDS             244868..245617
                     /locus_tag="BCG_0221"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_976319.1"
                     /db_xref="GI:121636096"
                     /db_xref="GeneID:4697419"
                     /translation="MTNDKMLARIAALLRQAEGTDNPHEADAFMSTAQRLATAASIDL
                     AVARSHAGNRSPAQAPTQRTITIGAAGTRGLRTYVQLFVLIAAANDVRCDVASNSTFV
                     YAYGFAEDIDTSHALYASLVVQMVRASDAYLASGAHRPTPTITARLNFQLAFGARVGQ
                     RLADAREQTRQEATKDRDRPPGTAIALRDKDIELHEYYRRSSKARGAWRASRATAGYS
                     SAARRAGDRAGRQARLGNNPELPGARAALGR"
     misc_feature    244877..245002
                     /locus_tag="BCG_0221"
                     /note="Protein of unknown function (DUF2786); Region:
                     DUF2786; pfam10979"
                     /db_xref="CDD:256224"
     gene            245614..246123
                     /locus_tag="BCG_0222"
                     /db_xref="GeneID:4695540"
     CDS             245614..246123
                     /locus_tag="BCG_0222"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_976320.1"
                     /db_xref="GI:121636097"
                     /db_xref="GeneID:4695540"
                     /translation="MIGADVPRDSQRARVYAAEAFVRTLFDRVTAHGSPTVEFFGTQL
                     TLPPEGRFGSVASVQRYVDDVLALPAVGQNWPTVSPVRVRARRAATAAHYENHGGTGT
                     IAVPDRHTAGWAMRELVVLHEVAHHLCQVPPPHGPEFVATVCTLTELVMGPEVGHVFR
                     VVYAQEGVR"
     misc_feature    245635..246117
                     /locus_tag="BCG_0222"
                     /note="putative metallohydrolase, TIGR04338 family;
                     Region: HEXXH_Rv0185"
                     /db_xref="CDD:234552"
     gene            246168..248243
                     /gene="bglS"
                     /locus_tag="BCG_0223"
                     /db_xref="GeneID:4697390"
     CDS             246168..248243
                     /gene="bglS"
                     /locus_tag="BCG_0223"
                     /EC_number="3.2.1.21"
                     /note="Differs from Mb0192 by 1aa, S504I, and from Rv0186
                     by 2aa, S504I, R532P"
                     /codon_start=1
                     /transl_table=11
                     /product="beta-glucosidase bglS"
                     /protein_id="YP_976321.1"
                     /db_xref="GI:121636098"
                     /db_xref="GeneID:4697390"
                     /translation="MTDDERFSLLVGLTGASDLWPVRDERIPQGVPMCAGYVPGIPRL
                     GVPALLMSDAGLGVTNPGYRPGDTATALPAGLALAASFNPVLARSSGKAIGREARSRG
                     FNVQLAGAINLARDPRNGRNFEYLSEDPLLSATMAAESIIGIQQQGVIATTKHFSLNC
                     NETNRHWLDAVIDPDAHRESDLLAFEIVIERSQPGAVMAAYNKVNGDYAAGNDHLLND
                     VLKGAWGYRGWVMSDWGGTPSWECALAGLDQECGAQIDAVLWQSEAFTDRLRAAYADG
                     NLPKGRLSDMVRRILRSMFAVGIDRWKPAPAPDMNAHNEIAAQMARQGIVLLQNRGLL
                     PLAPESAGRIAVIGGYAHLGVPAGYGSSAVTPPGGYAGVIPIGGSGLAAGLRNLYLLP
                     SSPLSELRKRLPNAQFEFDPGINPAEAVLAARRADIAIVFAIRAEGEGFDSADLSLPW
                     GQDALIAAVASANANTVVVLETGNPVTMPWRDSVNAIMQAWYPGQAGGQAVAESVTGQ
                     VNPSGRLPITFPVDLGQTPRSQPRELGAPWGTSTTIHYTEGADVGYRWFASTNQTPMF
                     AFGHGLSYTSFEYRDLVVTGGHTVHASFSVTNTGDRSGADVPQLYMIAAPGESRLRLL
                     GFERVELEPGQTRRVRIEADPRLLARYDGEARSWRIEPGGYTVAVGASAVALKLAAKV
                     KLAGRGFGR"
     misc_feature    246237..248177
                     /gene="bglS"
                     /locus_tag="BCG_0223"
                     /note="Probable beta-xylosidase; Provisional; Region:
                     PLN03080"
                     /db_xref="CDD:178629"
     misc_feature    246261..247319
                     /gene="bglS"
                     /locus_tag="BCG_0223"
                     /note="Beta-glucosidase-related glycosidases [Carbohydrate
                     transport and metabolism]; Region: BglX; COG1472"
                     /db_xref="CDD:224389"
     misc_feature    247140..247892
                     /gene="bglS"
                     /locus_tag="BCG_0223"
                     /note="Glycosyl hydrolase family 3 C-terminal domain;
                     Region: Glyco_hydro_3_C; pfam01915"
                     /db_xref="CDD:250964"
     misc_feature    247983..248186
                     /gene="bglS"
                     /locus_tag="BCG_0223"
                     /note="Fibronectin type III-like domain; Region: Fn3-like;
                     pfam14310"
                     /db_xref="CDD:258486"
     gene            248604..249266
                     /locus_tag="BCG_0224"
                     /db_xref="GeneID:4696688"
     CDS             248604..249266
                     /locus_tag="BCG_0224"
                     /EC_number="2.1.1.-"
                     /note="Differs from Rv0187 and Mb0193 by 1aa, V147A"
                     /codon_start=1
                     /transl_table=11
                     /product="o-methyltransferase"
                     /protein_id="YP_976322.1"
                     /db_xref="GI:121636099"
                     /db_xref="GeneID:4696688"
                     /translation="MGMDQQPNPPDVDAFLDSTLVGDDPALAAALAASDAAELPRIAV
                     SAQQGKFLCLLAGAIQARRVLEIGTLGGFSTIWLARGAGPQGRVVTLEYQPKHAEVAR
                     VNLQRAGVADRVEVVVGPALDTLPTLAGGPFDLVFIDADKENNVVYIQWAIRLARRGA
                     VIVVDNVIRGGGILAESDDADAVAARRTLQMMGEHPGLDATAIQTVGRKGWDGFALAL
                     VR"
     misc_feature    248790..249095
                     /locus_tag="BCG_0224"
                     /note="S-adenosylmethionine-dependent methyltransferases
                     (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes
                     that use S-adenosyl-L-methionine (SAM or AdoMet) as a
                     substrate for methyltransfer, creating the product
                     S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases;
                     cd02440"
                     /db_xref="CDD:100107"
     misc_feature    order(248802..248822,248877..248882,248958..248966)
                     /locus_tag="BCG_0224"
                     /note="S-adenosylmethionine binding site [chemical
                     binding]; other site"
                     /db_xref="CDD:100107"
     gene            249385..249816
                     /locus_tag="BCG_0225"
                     /db_xref="GeneID:4697406"
     CDS             249385..249816
                     /locus_tag="BCG_0225"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_976323.1"
                     /db_xref="GI:121636100"
                     /db_xref="GeneID:4697406"
                     /translation="MSTVHSSIDQHPDLLALRASFDRAAESTIAHFTFGLALLAGLYV
                     AASPWIVGFSATRGLPTCDLIVGIAVAYLAYGFASALDRTHGMTWTLPVLGVWVIFSP
                     WVLPGVAVTAGMMWSHIIAGAVVAVLGFYFGMRTRAAANQG"
     misc_feature    249481..249633
                     /locus_tag="BCG_0225"
                     /note="SPW repeat; Region: SPW; pfam03779"
                     /db_xref="CDD:202765"
     misc_feature    249643..249798
                     /locus_tag="BCG_0225"
                     /note="SPW repeat; Region: SPW; pfam03779"
                     /db_xref="CDD:202765"
     gene            complement(249895..251622)
                     /gene="ilvD"
                     /locus_tag="BCG_0226c"
                     /db_xref="GeneID:4697026"
     CDS             complement(249895..251622)
                     /gene="ilvD"
                     /locus_tag="BCG_0226c"
                     /EC_number="4.2.1.9"
                     /note="catalyzes the dehydration of
                     2,3-dihydroxy-3-methylbutanoate to 3-methyl-2-oxobutanoate
                     in valine and isoleucine biosynthesis"
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroxy-acid dehydratase"
                     /protein_id="YP_976324.1"
                     /db_xref="GI:121636101"
                     /db_xref="GeneID:4697026"
                     /translation="MPQTTDEAASVSTVADIKPRSRDVTDGLEKAAARGMLRAVGMDD
                     EDFAKPQIGVASSWNEITPCNLSLDRLANAVKEGVFSAGGYPLEFGTISVSDGISMGH
                     EGMHFSLVSREVIADSVEVVMQAERLDGSVLLAGCDKSLPGMLMAAARLDLAAVFLYA
                     GSILPGRAKLSDGSERDVTIIDAFEAVGACSRGLMSRADVDAIERAICPGEGACGGMY
                     TANTMASAAEALGMSLPGSAAPPATDRRRDGFARRSGQAVVELLRRGITARDILTKEA
                     FENAIAVVMAFGGSTNAVLHLLAIAHEANVALSLQDFSRIGSGVPHLADVKPFGRHVM
                     SDVDHIGGVPVVMKALLDAGLLHGDCLTVTGHTMAENLAAITPPDPDGKVLRALANPI
                     HPSGGITILHGSLAPEGAVVKTAGFDSDVFEGTARVFDGERAALDALEDGTITVGDAV
                     VIRYEGPKGGPGMREMLAITGAIKGAGLGKDVLLLTDGRFSGGTTGLCVGHIAPEAVD
                     GGPIALLRNGDRIRLDVAGRVLDVLADPAEFASRQQDFSPPPPRYTTGVLSKYVKLVS
                     SAAVGAVCG"
     misc_feature    complement(249901..251568)
                     /gene="ilvD"
                     /locus_tag="BCG_0226c"
                     /note="dihydroxy-acid dehydratase; Provisional; Region:
                     PRK00911"
                     /db_xref="CDD:234861"
     gene            251770..252060
                     /locus_tag="BCG_0227"
                     /db_xref="GeneID:4699341"
     CDS             251770..252060
                     /locus_tag="BCG_0227"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_976325.1"
                     /db_xref="GI:121636102"
                     /db_xref="GeneID:4699341"
                     /translation="MTAAHGYTQQKDNYAKRLRRVEGQVRGIARMIEEDKYCIDVLTQ
                     ISAVTSALRSVALNLLDEHLSHCVTRAVAEGGPGADGKLAEASAAIARLVRS"
     misc_feature    251800..252045
                     /locus_tag="BCG_0227"
                     /note="Transcriptional regulators CsoR (copper-sensitive
                     operon repressor), RcnR, and FrmR, and related domains;
                     this domain superfamily was previously known as DUF156;
                     Region: CsoR-like_DUF156; cd10148"
                     /db_xref="CDD:197385"
     misc_feature    order(251800..251802,251809..251814,251821..251826,
                     251833..251835,251842..251847,251851..251856,
                     251863..251874,251878..251886,251890..251898,
                     251902..251907,251911..251916,251923..251928,
                     251935..251940,251944..251952,251956..251964,
                     251971..251973,252004..252009,252013..252042)
                     /locus_tag="BCG_0227"
                     /note="putative homotetramer interface [polypeptide
                     binding]; other site"
                     /db_xref="CDD:197385"
     misc_feature    order(251800..251802,251809..251814,251821..251826,
                     251833..251835,251842..251847,251851..251856,
                     251863..251874,251878..251886,251890..251898,
                     251902..251907,251911..251916,251923..251928,
                     251935..251937,251944..251946,251956..251958,
                     252022..252024,252031..252042)
                     /locus_tag="BCG_0227"
                     /note="putative homodimer interface [polypeptide binding];
                     other site"
                     /db_xref="CDD:197385"
     misc_feature    order(251878..251880,251956..251958,252022..252024)
                     /locus_tag="BCG_0227"
                     /note="putative allosteric switch controlling residues;
                     other site"
                     /db_xref="CDD:197385"
     misc_feature    order(251881..251883,251956..251958,251968..251970)
                     /locus_tag="BCG_0227"
                     /note="putative metal binding site [ion binding]; other
                     site"
                     /db_xref="CDD:197385"
     misc_feature    order(251938..251940,251947..251952,251959..251964,
                     251968..251973,252004..252009,252013..252021,
                     252025..252030)
                     /locus_tag="BCG_0227"
                     /note="putative homodimer-homodimer interface [polypeptide
                     binding]; other site"
                     /db_xref="CDD:197385"
     gene            252188..253429
                     /locus_tag="BCG_0228"
                     /db_xref="GeneID:4696104"
     CDS             252188..253429
                     /locus_tag="BCG_0228"
                     /codon_start=1
                     /transl_table=11
                     /product="integral membrane protein"
                     /protein_id="YP_976326.1"
                     /db_xref="GI:121636103"
                     /db_xref="GeneID:4696104"
                     /translation="MTAPTGTSATTTRPWTPRIATQLSVLACAAFIYVTAEILPVGAL
                     SAIARNLRVSVVLVGTLLSWYALVAAVTTVPLVRWTAHWPRRRALVVSLVCLTVSQLV
                     SALAPNFAVLAAGRVLCAVTHGLLWAVIAPIATRLVPPSHAGRATTSIYIGTSLALVV
                     GSPLTAAMSLMWGWRLAAVCVTGAAAAVALAARLALPEMVLRADQLEHVGRRARHHRN
                     PRLVKVSVLTMIAVTGHFVSYTYIVVIIRDVVGVRGPNLAWLLAAYGVAGLVSVPLVA
                     RPLDRWPKGAVIVGMTGLTAAFTLLTALAFGERHTAATALLGTGAIVLWGALATAVSP
                     MLQSAAMRSGGDDPDGASGLYVTAFQIGIMAGALLGGLLYERSLAMMLTASAGLMGVA
                     LFGMTVSQHLFENPTLSPGDG"
     misc_feature    252212..253414
                     /locus_tag="BCG_0228"
                     /note="Arabinose efflux permease [Carbohydrate transport
                     and metabolism]; Region: AraJ; COG2814"
                     /db_xref="CDD:225371"
     misc_feature    252254..253369
                     /locus_tag="BCG_0228"
                     /note="The Major Facilitator Superfamily (MFS) is a large
                     and diverse group of secondary transporters that includes
                     uniporters, symporters, and antiporters. MFS proteins
                     facilitate the transport across cytoplasmic or internal
                     membranes of a variety of...; Region: MFS; cd06174"
                     /db_xref="CDD:119392"
     misc_feature    order(252296..252298,252305..252313,252317..252322,
                     252371..252373,252380..252385,252392..252394,
                     252404..252409,252413..252418,252554..252559,
                     252566..252571,252578..252583,252590..252592,
                     252626..252631,252638..252643,252659..252661,
                     252881..252883,252890..252895,252902..252907,
                     252914..252916,252956..252958,252968..252970,
                     252980..252982,252989..252991,253001..253003,
                     253163..253165,253172..253177,253184..253186,
                     253196..253201,253208..253210,253238..253243,
                     253250..253255,253262..253267,253274..253276)
                     /locus_tag="BCG_0228"
                     /note="putative substrate translocation pore; other site"
                     /db_xref="CDD:119392"
     gene            253506..254564
                     /locus_tag="BCG_0229"
                     /db_xref="GeneID:4698256"
     CDS             253506..254564
                     /locus_tag="BCG_0229"
                     /note="In Mycobacterium tuberculosis strain H37Rv, Rv0192
                     and Rv0192A exist as 2 genes with an overlap region. In
                     Mycobacterium bovis BCG Pasteur, and Mycobacterium bovis,
                     a single base insertion (*-g) leads to a single product.
                     Differs from Mb0198 by 1aa, A279V and from Rv0192 by 2aa,
                     P113S, A279V"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_976327.1"
                     /db_xref="GI:121636104"
                     /db_xref="GeneID:4698256"
                     /translation="MSRWKQGWTRGSLFAALNIAAVVAVLMLGAGVAVADPDAAPGDP
                     GGPGGPGGTAGPVDPPAVDLLAPPPDPLALPPALDPLAPPPPDPLAPPPPDPLAVPVA
                     AGPVAGQDPTPFVGPPPFRPPTFNPVDGAMVGVAKPIVINFAVPIADRAMAESAIHIS
                     SIPPVPGKFYWMSPTQVRWRPFEFWPANTAVNIDAAGTKSSFRTGDSLVATADDATHQ
                     MTITRNGVVQKTFPMSMGMVSGGHQTPNGTYYVLEKFATVVMDSSTYGVPVNSAQGYK
                     LTASDAVRIDNSGNFVHSAPWSVADQGKRNVTHGCINLSPANAKWFYDNFGSGDPVVV
                     KNSVGTYNKNDGAQDWQI"
     misc_feature    253842..254126
                     /locus_tag="BCG_0229"
                     /note="IgD-like repeat domain of mycobacterial
                     L,D-transpeptidases; Region: LDT_IgD_like_1; cd13431"
                     /db_xref="CDD:240446"
     misc_feature    253869..254519
                     /locus_tag="BCG_0229"
                     /note="Uncharacterized protein conserved in bacteria
                     [Function unknown]; Region: ErfK; COG1376"
                     /db_xref="CDD:224294"
     misc_feature    254130..254507
                     /locus_tag="BCG_0229"
                     /note="L,D-transpeptidase catalytic domain; Region: YkuD;
                     pfam03734"
                     /db_xref="CDD:252135"
     gene            complement(254624..256471)
                     /locus_tag="BCG_0230c"
                     /db_xref="GeneID:4698698"
     CDS             complement(254624..256471)
                     /locus_tag="BCG_0230c"
                     /note="Differs from Rv0193c and Mb0199c by 1aa, E417K"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_976328.1"
                     /db_xref="GI:121636105"
                     /db_xref="GeneID:4698698"
                     /translation="MIQISRDMSSLGQTATTQALPDNSDGIQLTKFAADDILPLEYAP
                     PIGPELVSQDQLPAAWAYKRFRDLDDKESYRRKLLQELTDALAAQGSEAAEIATAALR
                     DLIDQMAEQGAVVLADIVESDDFLELVKRYDELMAREGSRSFIHRFLDLRRSPGMLTD
                     PAVNGALVHPLMIALISYAVGGPIRMIDARGKDAEPLSVLAQDNMLHIDNTPFNDEYK
                     ILITWRRGTAQGPAGQNFTFLPGTHKLARTCFVNEDGVPWSSENASIFTTPDSIRKVF
                     DAQRQLGGQDHPTVIEVTDSERPLSSVFAAGSLVHHRFRTASGSARSCIILVFHRVAD
                     NPGRMVSDVEDSSDVSLSELLTRGVPDESYQQRFIATLCAAADEIAELLLKWKKTPQR
                     PVSLPLQTKQIDGARFEEWISAATEAPEVREIRNRELTIPYGEVLSAEEFFDLIWRLM
                     RFDKHGPLDLILYHDNREEPRKWARNLIREMSADRLYERLLGWLADIQQPRPADCLRP
                     LQIHALISEVLKTLPLDEDQDPPADWHFDLLGMSHAEAARSVKHLLEDVAEALLRCED
                     MAAYLSTSLFAFWAVDAAYSLDGRRNLVVKDCARRLLRHYTMLSLTCFQ"
     gene            256778..260362
                     /locus_tag="BCG_0231"
                     /db_xref="GeneID:4698450"
     CDS             256778..260362
                     /locus_tag="BCG_0231"
                     /note="Differs from Mb0200 by 1aa, I49V, and from Rv0194
                     by 2aa, T74M, M223T"
                     /codon_start=1
                     /transl_table=11
                     /product="drugs-transport transmembrane ATP-binding
                     protein ABC transporter"
                     /protein_id="YP_976329.1"
                     /db_xref="GI:121636106"
                     /db_xref="GeneID:4698450"
                     /translation="MRTNCWWRLSGYVMRHRRDLLLGFGAALAGTVIAVLVPLVTKRV
                     IDDAIAADHRPLAPWAVVLVAAAGATYLLTYVRRYYGGRIAHLVQHDLRMDAFQALLR
                     WDGRQQDRWSSGQLIVRTTNDLQLVQALLFDVPNVLRHVLTLLLGVAVMTWLSVPLAL
                     LAVLLVPVIGLIAHRSRRLLAAATHCAQEHKAAVTGVVDAAVCGIRVVKAFGQEERET
                     VKLVMASRALYAAQLRVARLNAHFGPLLQTLPALGQMAVFALGGWMAAQGSITVGTFV
                     AFWACLTLLARPACDLAGMLTIAQQARAGAVRVLELIDSRPTLVDGTKPLSLEARLSL
                     EFQRVSFGYVADRPVLREISLSVRAGETLAVVGAPGSGKSTLASLATRCYDVTQGAVR
                     IGGQDVRELTLDSLRSAIGLVPEDAVLFSGTIGANIAYGRPDATPEQIATAARAAHIE
                     EFVNTLPDGYQTAVGARGLTLSGGQRQRIALARALLHQPRLLIMDDPTSAVDAVIECG
                     IQEVLREAIADRTAVIFTRRRSMLTLADRVAVLDSGRLLDVGTPDEVWERCPRYRELL
                     SPAPDLADDLVVAERSPVCRPVAGLGTKAAQHTNVHNPGPHDHPPGPDPLRRLLREFR
                     GPLALSLLLVAVQTCAGLLPPLLIRHGIDVGIRRHVLSALWWAALAGTATVVIRWVVQ
                     WGSAMVAGYTGEQVLFRLRSVVFAHAQRLGLDAFEDDGDAQIVTAVTADVEAIVAFLR
                     TGLVVAVISVVTLVGILVALLAIRARLVLLIFTTMPVLALATWQFRRASNWTYRRARH
                     RLGTVTATLREYAAGLRIAQAFRAEYRGLQSYFAHSDDYRRLGVRGQRLLALYYPFVA
                     LLCSLATTLVLLDGAREVRAGVISVGALVTYLLYIELLYTPIGELAQMFDDYQRAAVA
                     AGRIRSLLSTRTPSSPAARPVGTLRGEVVFDAVHYSYRTREVPALAGINLRIPAGQTV
                     VFVGSTGSGKSTLIKLVARFYDPTHGTVRVDGCDLREFDVDGYRNRLGIVTQEQYVFA
                     GTVRDAIAYGRPDATDAQVERAAREVGAHPMITALDNGYLHQVTAGGRNLSAGQLQLL
                     ALARARLVDPDILLLDEATVALDPATEAVVQRATLTLAARRTTLIVAHGLAIAEHADR
                     IVVLEHGTVVEDGAHTELLAAGGHYSRLWAAHTRLCSPEITQLQCIDA"
     misc_feature    256793..258472
                     /locus_tag="BCG_0231"
                     /note="ABC-type multidrug transport system, ATPase and
                     permease components [Defense mechanisms]; Region: MdlB;
                     COG1132"
                     /db_xref="CDD:224055"
     misc_feature    256835..257611
                     /locus_tag="BCG_0231"
                     /note="ABC transporter transmembrane region; Region:
                     ABC_membrane; pfam00664"
                     /db_xref="CDD:250039"
     misc_feature    257777..258472
                     /locus_tag="BCG_0231"
                     /note="ATP-binding cassette transporter nucleotide-binding
                     domain; Region: ABC_ATPase; cl17201"
                     /db_xref="CDD:266551"
     misc_feature    257876..257899
                     /locus_tag="BCG_0231"
                     /note="Walker A/P-loop; other site"
                     /db_xref="CDD:213179"
     misc_feature    order(257885..257890,257894..257902,258020..258022,
                     258260..258265,258356..258358)
                     /locus_tag="BCG_0231"
                     /note="ATP binding site [chemical binding]; other site"
                     /db_xref="CDD:213179"
     misc_feature    258011..258022
                     /locus_tag="BCG_0231"
                     /note="Q-loop/lid; other site"
                     /db_xref="CDD:213179"
     misc_feature    258188..258217
                     /locus_tag="BCG_0231"
                     /note="ABC transporter signature motif; other site"
                     /db_xref="CDD:213179"
     misc_feature    258248..258265
                     /locus_tag="BCG_0231"
                     /note="Walker B; other site"
                     /db_xref="CDD:213179"
     misc_feature    258272..258283
                     /locus_tag="BCG_0231"
                     /note="D-loop; other site"
                     /db_xref="CDD:213179"
     misc_feature    258344..258364
                     /locus_tag="BCG_0231"
                     /note="H-loop/switch region; other site"
                     /db_xref="CDD:213179"
     misc_feature    258686..260314
                     /locus_tag="BCG_0231"
                     /note="ABC-type multidrug transport system, ATPase and
                     permease components [Defense mechanisms]; Region: MdlB;
                     COG1132"
                     /db_xref="CDD:224055"
     misc_feature    258686..259471
                     /locus_tag="BCG_0231"
                     /note="ABC transporter transmembrane region; Region:
                     ABC_membrane; pfam00664"
                     /db_xref="CDD:250039"
     misc_feature    259601..260302
                     /locus_tag="BCG_0231"
                     /note="ATP-binding cassette transporter nucleotide-binding
                     domain; Region: ABC_ATPase; cl17201"
                     /db_xref="CDD:266551"
     misc_feature    259703..259726
                     /locus_tag="BCG_0231"
                     /note="Walker A/P-loop; other site"
                     /db_xref="CDD:213179"
     misc_feature    order(259712..259717,259721..259729,259847..259849,
                     260087..260092,260183..260185)
                     /locus_tag="BCG_0231"
                     /note="ATP binding site [chemical binding]; other site"
                     /db_xref="CDD:213179"
     misc_feature    259838..259849
                     /locus_tag="BCG_0231"
                     /note="Q-loop/lid; other site"
                     /db_xref="CDD:213179"
     misc_feature    260015..260044
                     /locus_tag="BCG_0231"
                     /note="ABC transporter signature motif; other site"
                     /db_xref="CDD:213179"
     misc_feature    260075..260092
                     /locus_tag="BCG_0231"
                     /note="Walker B; other site"
                     /db_xref="CDD:213179"
     misc_feature    260099..260110
                     /locus_tag="BCG_0231"
                     /note="D-loop; other site"
                     /db_xref="CDD:213179"
     misc_feature    260171..260191
                     /locus_tag="BCG_0231"
                     /note="H-loop/switch region; other site"
                     /db_xref="CDD:213179"
     gene            260800..261435
                     /locus_tag="BCG_0232"
                     /db_xref="GeneID:4695751"
     CDS             260800..261435
                     /locus_tag="BCG_0232"
                     /codon_start=1
                     /transl_table=11
                     /product="LuxR family two component transcriptional
                     regulator"
                     /protein_id="YP_976330.1"
                     /db_xref="GI:121636107"
                     /db_xref="GeneID:4695751"
                     /translation="MAPVNVISVAVVASDPLTRDGALARLSSHRELDVRAWQAGCETS
                     VLLVLATTITAPLLCQIEDVQKDGPSHAPKLVVVADEFSAEQVFRMIKLGLTGLLYRS
                     QSTFDCIVETIRLSAEGRLRLPERVQRYLVGRIKSTPTAEPDTPCAAALAEREVAVLR
                     LLADGLSTHQVAVQLNYCERTIKNIVHDIVTRLKLRNRTHAVAHALRAGLI"
     misc_feature    260818..261432
                     /locus_tag="BCG_0232"
                     /note="Response regulator containing a CheY-like receiver
                     domain and an HTH DNA-binding domain [Signal transduction
                     mechanisms / Transcription]; Region: CitB; COG2197"
                     /db_xref="CDD:225107"
     misc_feature    261250..261420
                     /locus_tag="BCG_0232"
                     /note="C-terminal DNA-binding domain of LuxR-like
                     proteins. This domain contains a helix-turn-helix motif
                     and binds DNA. Proteins belonging to this group are
                     response regulators; some act as transcriptional
                     activators, others as transcriptional repressors. Many...;
                     Region: LuxR_C_like; cd06170"
                     /db_xref="CDD:99777"
     misc_feature    order(261253..261261,261298..261306,261328..261333,
                     261337..261342,261346..261360,261391..261393)
                     /locus_tag="BCG_0232"
                     /note="DNA binding residues [nucleotide binding]"
                     /db_xref="CDD:99777"
     misc_feature    order(261286..261288,261292..261294,261298..261300,
                     261391..261399,261406..261408,261415..261420)
                     /locus_tag="BCG_0232"
                     /note="dimerization interface [polypeptide binding]; other
                     site"
                     /db_xref="CDD:99777"
     gene            261548..262132
                     /locus_tag="BCG_0233"
                     /db_xref="GeneID:4695509"
     CDS             261548..262132
                     /locus_tag="BCG_0233"
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulatory protein"
                     /protein_id="YP_976331.1"
                     /db_xref="GI:121636108"
                     /db_xref="GeneID:4695509"
                     /translation="MQGPRERMVVSAALLIRERGAHATAISDVLQHSGAPRGSAYHYF
                     PGGRTQLLCEAVDYAGEHVAAMINEAEGGLELLDALIDKYRQQLLSTDFRAGCPIAAV
                     SVEAGDEQDRERMAPVIARAAAVFDRWSDLTAQRFIADGIPPDRAHELAVLATSTLEG
                     AILLARVRRDLTPLDLVHRQLRNLLLAELPERSR"
     misc_feature    261560..262066
                     /locus_tag="BCG_0233"
                     /note="Transcriptional regulator [Transcription]; Region:
                     AcrR; COG1309"
                     /db_xref="CDD:224228"
     misc_feature    261572..261685
                     /locus_tag="BCG_0233"
                     /note="Bacterial regulatory proteins, tetR family; Region:
                     TetR_N; pfam00440"
                     /db_xref="CDD:249860"
     gene            262132..264378
                     /locus_tag="BCG_0234"
                     /db_xref="GeneID:4695763"
     CDS             262132..264378
                     /locus_tag="BCG_0234"
                     /EC_number="1.-.-.-"
                     /note="In Mycobacterium bovis BCG Pasteur, and
                     Mycobacterium bovis, a single base transversion (t-g)
                     introduces a stop codon that leads to a shorter product
                     compared to its homolog in Mycobacterium tuberculosis
                     strain H37Rv (748 aa versus 762 aa). Differs from Rv0197
                     by 1aa, S378R"
                     /codon_start=1
                     /transl_table=11
                     /product="oxidoreductase"
                     /protein_id="YP_976332.1"
                     /db_xref="GI:121636109"
                     /db_xref="GeneID:4695763"
                     /translation="MTSSDWLPTACILCECNCGIVVQVDDRRLARIRGDKAHPGSAGY
                     TCNKALRLDHYQNNRARLSSPMRRRADGTYEEIDWDTAIVEIAEGFKQIRDTHGGDKI
                     FYYGGGGQGNHLGGAYSGAFLKALGSRYRSNALAQEKTGEAWVDFQLYGGHTRGEFEN
                     AEVSVFVGKNPWMSQSFPRARVVLNEIAKDPGRSMIVIDPVVTDTAKMADFHLRVQPG
                     CDAWCLAALAAVLVQENLCNEAFLAAHVHGVDTVRAALQEVPVADYAQRCGVDEELLR
                     AAARRIGTAASVSVFEDLGIQQAPNSTVCSYLNKLLWILTGNFAKKGGQHLHSSFAPL
                     FSQVSGRTPVTGAPIIAGLIPGNVVPEEILTEHPDRFRAMIVESGNPAHSLADSAACR
                     AAFQALELMVVVDVAMTETARLAHYVLPAASQFEKPEATFFNFEFPRNGFQLRRPLFP
                     PLPGTLPEPEIWARLVRALGVVDEADLRPLREAAAQGRQAYTEAFLAAAATNPTVAKL
                     TAYVLYETLGPTLPDGLAGAAALWGLAQKTAMAYPDAVRRAGHADGNALFDAILERPS
                     GVTFTVHNYEDDFALISHPDHKIALEIPEMLAEIRSLTQTPSRLTTPQLPIVLSVGER
                     RAYTANDIFRDPSWRKRDANGALRVSVEDAQALGLADGCLARITTAAGSAEATVEVTE
                     TMLAGHAALPNGFGLDYTGDDGRTVVAGVAPNALTSTRWRDPYAGTPWHKHVPAAIRR
                     ADAESPIW"
     misc_feature    262132..264357
                     /locus_tag="BCG_0234"
                     /note="Anaerobic dehydrogenases, typically
                     selenocysteine-containing [Energy production and
                     conversion]; Region: BisC; COG0243"
                     /db_xref="CDD:223321"
     misc_feature    262153..263940
                     /locus_tag="BCG_0234"
                     /note="The MopB_1 CD includes a group of related
                     uncharacterized bacterial molybdopterin-binding
                     oxidoreductase-like domains with a putative N-terminal
                     iron-sulfur [4Fe-4S] cluster binding site and
                     molybdopterin cofactor binding site. These members belong
                     to...; Region: MopB_1; cd02762"
                     /db_xref="CDD:239163"
     misc_feature    order(262162..262164,262171..262173,262183..262185,
                     262267..262269)
                     /locus_tag="BCG_0234"
                     /note="putative [Fe4-S4] binding site [ion binding]; other
                     site"
                     /db_xref="CDD:239163"
     misc_feature    order(262273..262275,262519..262521,262525..262533,
                     262630..262635,262639..262641,262648..262653,
                     262723..262731,262789..262791,263008..263019,
                     263122..263127,263263..263271,263341..263349,
                     263356..263358,263392..263397,263410..263412)
                     /locus_tag="BCG_0234"
                     /note="putative molybdopterin cofactor binding site
                     [chemical binding]; other site"
                     /db_xref="CDD:239163"
     misc_feature    263971..264354
                     /locus_tag="BCG_0234"
                     /note="The MopB_CT_1 CD includes a group of related
                     uncharacterized bacterial molybdopterin-binding
                     oxidoreductase-like domains with a putative N-terminal
                     iron-sulfur [4Fe-4S] cluster binding site and
                     molybdopterin cofactor binding site. This CD is of the...;
                     Region: MopB_CT_1; cd02782"
                     /db_xref="CDD:239183"
     misc_feature    order(263992..264006,264010..264021,264208..264210,
                     264271..264273,264331..264336)
                     /locus_tag="BCG_0234"
                     /note="putative molybdopterin cofactor binding site; other
                     site"
                     /db_xref="CDD:239183"
     gene            complement(264419..266410)
                     /locus_tag="BCG_0235c"
                     /db_xref="GeneID:4696246"
     CDS             complement(264419..266410)
                     /locus_tag="BCG_0235c"
                     /EC_number="3.4.24.-"
                     /codon_start=1
                     /transl_table=11
                     /product="zinc metalloprotease"
                     /protein_id="YP_976333.1"
                     /db_xref="GI:121636110"
                     /db_xref="GeneID:4696246"
                     /translation="MTLAIPSGIDLSHIDADARPQDDLFGHVNGRWLAEHEIPADRAT
                     DGAFRSLFDRAETQVRDLIIQASQAGAAVGTDAQRIGDLYASFLDEEAVERAGVQPLH
                     DELATIDSAADATELAAALGTLQRAGVGGGIGVYVDTDSKDSTRYLVHFTQSGIGLPD
                     ESYYRDEQHAAVLAAYPGHIARMFGLVYGGESRDHAKTADRIVALETKLADAHWDVVK
                     RRDADLGYNLRTFAQLQTEGAGFDWVSWVTALGSAPDAMTELVVRQPDYLVTFASLWA
                     SVNVEDWKCWARWRLIRARAPWLTRALVAEDFEFYGRTLTGAQQLRDRWKRGVSLVEN
                     LMGDAVGKLYVQRHFPPDAKSRIDTLVDNLQEAYRISISELDWMTPQTRQRALAKLNK
                     FTAKVGYPIKWRDYSKLAIDRDDLYGNVQRGYAVNHDRELAKLFGPVDRDEWFMTPQT
                     VNAYYNPGMNEIVFPAAILQPPFFDPQADEAANYGGIGAVIGHEIGHGFDDQGAKYDG
                     DGNLVDWWTDDDRTEFAARTKALIEQYHAYTPRDLVDHPGPPHVQGAFTIGENIGDLG
                     GLSIALLAYQLSLNGNPAPVIDGLTGMQRVFFGWAQIWRTKSRAAEAIRRLAVDPHSP
                     PEFRCNGVVRNVDAFYQAFDVTEDDALFLDPQRRVRIWN"
     misc_feature    complement(264425..266410)
                     /locus_tag="BCG_0235c"
                     /note="Predicted metalloendopeptidase [Posttranslational
                     modification, protein turnover, chaperones]; Region: PepO;
                     COG3590"
                     /db_xref="CDD:226118"
     misc_feature    complement(264431..266359)
                     /locus_tag="BCG_0235c"
                     /note="Peptidase family M13 includes neprilysin,
                     endothelin-converting enzyme I; Region: M13; cd08662"
                     /db_xref="CDD:189000"
     misc_feature    complement(order(264527..264529,264545..264547,
                     264608..264613,264731..264733,264920..264922,
                     264929..264934,264941..264943,265052..265057))
                     /locus_tag="BCG_0235c"
                     /note="active site"
                     /db_xref="CDD:189000"
     misc_feature    complement(order(264731..264733,264920..264922,
                     264932..264934))
                     /locus_tag="BCG_0235c"
                     /note="Zn binding site [ion binding]; other site"
                     /db_xref="CDD:189000"
     gene            266453..267112
                     /locus_tag="BCG_0236"
                     /db_xref="GeneID:4696352"
     CDS             266453..267112
                     /locus_tag="BCG_0236"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_976334.1"
                     /db_xref="GI:121636111"
                     /db_xref="GeneID:4696352"
                     /translation="MPDGEQSQPPAQEDAEDDSRPDAAEAAAAEPKSSAGPMFSTYGI
                     ASTLLGVLSVAAVVLGAMIWSAHRDDSGERTYLTRVMLTAAEWTAVLINMNADNIDAS
                     LQRLHDGTVGQLNTDFDAVVQPYRQVVEKLRTHSSGRIEAVAIDTVHRELDTQSGAAR
                     PVVTTKLPPFATRTDSVLLVATSVSENAGAKPQTVHWNLRLDVSDVDGKLMISRLESI
                     R"
     gene            267109..267798
                     /locus_tag="BCG_0237"
                     /db_xref="GeneID:4696349"
     CDS             267109..267798
                     /locus_tag="BCG_0237"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_976335.1"
                     /db_xref="GI:121636112"
                     /db_xref="GeneID:4696349"
                     /translation="MRNAWRLVVFDVLAPLATIAALAAIGVLLGWPLWWVSTCSVLVL
                     LVVEGVAINFWLLRRDSVTVGTDDDAPGLRLAVVFLCAAAISAAVVTGYLRWTTPDRD
                     FNRDSREVVHLATGMAETVASFSPSAPAAAVDRAAAMMVPEHAGGFKEQYAKSSADLA
                     RRGVTAQAATLAAGVEAIGPSAASVAVILRVSQSIPGQPTSQAARALRVTLTKRGSGW
                     LVLDVTPINAR"
     gene            complement(267795..268298)
                     /locus_tag="BCG_0238c"
                     /db_xref="GeneID:4696741"
     CDS             complement(267795..268298)
                     /locus_tag="BCG_0238c"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_976336.1"
                     /db_xref="GI:121636113"
                     /db_xref="GeneID:4696741"
                     /translation="MTLAAEPHPAPPQQPTVAWSEPDVDRRVEFWPTVAIRSALESGD
                     IATWQRIAAALKRDPYGRTARQVEEVLEGIPATGIANAFWEVLDRARTHLDANERAEV
                     ARQVGLLLDRSGLQRQEFASRIGVTAQDLTAYLDGIVSPSASLMIRMRRLSDRFVRAK
                     SVRAADS"
     gene            complement(268295..271195)
                     /gene="mmpL11"
                     /locus_tag="BCG_0239c"
                     /db_xref="GeneID:4696794"
     CDS             complement(268295..271195)
                     /gene="mmpL11"
                     /locus_tag="BCG_0239c"
                     /codon_start=1
                     /transl_table=11
                     /product="transmembrane transport protein mmpL11"
                     /protein_id="YP_976337.1"
                     /db_xref="GI:121636114"
                     /db_xref="GeneID:4696794"
                     /translation="MMRLSRNLRRCRWLVFTGWLLALVPAVYLAMTQSGNLTGGGFEV
                     AGSQSLLVHDQLDAHYPDRGAPALALVAAPRPDASYQDIDNAVALLRQIASELPGVTE
                     APNPTQRPPQPDRPYVVSLRLDARNAGTSDVAKKLRDRIGVKGDQSGQTANGKVRLYV
                     IGQGALSAAAAANTKHDIANAERWNLPIILMVLVAVFGSLAAAAIPLALAVCTVVITM
                     GLVFVLSMHTTMSVFVTSTVSMFGIALAVDYSLFILMRYREELRCGRRPPDAVDAAMA
                     TSGLAVVLSGMTVIASLTGIYLINTPALRSMATGAILAVAVAMLTSATLTPAVLATFA
                     RAAAKRSALVHWSRRPASTQSWFWSRWVGWVMRRPWITALAASTVLLVMAAPATLMVL
                     GNSLLRQFDSSHEIRTGAAAAAQALGPGALGPVQVLVRFDAGGASAPEHSQTIAAIRH
                     RIAQAPNVVSVAPPRFADDNGSALLSAVLSVDPEDLGARDTITWMRTQLPRVAGAAQV
                     DVGGPTALIKDFDDRVSATQPLVLVFVAVIAFLMLLISIRSVFLAFKGVLMTLLSVAA
                     AYGSLVMVFQWGWARGLGFPALHSIDSTVPPLVLAMTFGLSMDYEIFLLTRIRERFLQ
                     TGQTRDAVAYGVRTSARTITSAALIMIAVFCGFAFAGMPLVAEIGVACAVAIAVDATV
                     VRLVLVPALMAMFDRWNWWLPRWLAHILPSVDFDRPLPKVDLGDVVVIPDDFAAAIPP
                     SADVRMVLKSAAKLKRLAPDAICVTDPLAFTGCGCDGKALDQVQLAYRNGIARAISWG
                     QRPVHPVTVWRKRLAVALDALQTTTWECGGVQTHRAGPGYRRRSPVETTNVALPTGDR
                     LQIPTGAETLRFKGYLIMSRNSSHDYADFADLVDTMAPETAAAVLAGMDRYYSCQAPG
                     RQWMATQLVGRLADPQPSDLGDQSPGADAQAKWEEVRRRCLSVAVAMLEEAR"
     misc_feature    complement(268502..271195)
                     /gene="mmpL11"
                     /locus_tag="BCG_0239c"
                     /note="Predicted drug exporters of the RND superfamily
                     [General function prediction only]; Region: COG2409"
                     /db_xref="CDD:225272"
     misc_feature    complement(270089..271063)
                     /gene="mmpL11"
                     /locus_tag="BCG_0239c"
                     /note="MMPL family; Region: MMPL; cl21543"
                     /db_xref="CDD:271963"
     misc_feature    complement(269084..269923)
                     /gene="mmpL11"
                     /locus_tag="BCG_0239c"
                     /note="MMPL family; Region: MMPL; cl21543"
                     /db_xref="CDD:271963"
     gene            271417..271827
                     /locus_tag="BCG_0240"
                     /db_xref="GeneID:4697541"
     CDS             271417..271827
                     /locus_tag="BCG_0240"
                     /note="Differs from Rv0203 and Mb0209 by 1aa, T88K"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_976338.1"
                     /db_xref="GI:121636115"
                     /db_xref="GeneID:4697541"
                     /translation="MKTGTATTRRRLLAVLIALALPGAAVALLAEPSATGASDPCAAS
                     EVARTVGSVAKSMGDYLDSHPETNQVMTAVLQQQVGPGSVASLTAHFEANPKVASDLH
                     ALSQPLTDLSTRCSLPISGLQAIGLMQAVQGARR"
     gene            complement(271879..273162)
                     /locus_tag="BCG_0241c"
                     /db_xref="GeneID:4696793"
     CDS             complement(271879..273162)
                     /locus_tag="BCG_0241c"
                     /note="In Mycobacterium bovis BCG Pasteur, and
                     Mycobacterium bovis, the presence of a more likely start
                     codon leads to a longer product compared to its homolog in
                     Mycobacterium tuberculosis strain H37Rv (427 a versus 412
                     aa). Differs from Rv0204c by 1aa, L321V"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_976339.1"
                     /db_xref="GI:121636116"
                     /db_xref="GeneID:4696793"
                     /translation="MYRDYGATCTVTLKHVSHDAPARNLRQRVGALPRTRVGAPPAEG
                     VPPRGKYWWLRWAVLAIVAIVLAIEVALGWDQLAKAWVSLYRAKWWWLLAAVAAAGAS
                     MHSFAQIQRTLLKSAGVHVKQWRSEAAFYAANSLSTTLPGGPVLSATFLLRQQRIWGA
                     STVVASWQLVMSGVLQAVGLALLGLGGAFFLGAKNNPFSLLFTLGGFVTLLLLAQAVA
                     SRPELIEGIGRRVLSWANSVRGRPADAGLPKWRETLMQLESVSLGRRDLGVAFGWSLF
                     NWIADVACLGFAAYAAGDHASVGGLAVAYAAARAVGTIPLMPGGLLVVEAVLVPGLVS
                     SGMPLPSAISAMLIYRLISWLLIAAIGWVVFFFMFRTESTADSDNDRDPPTDPNLRLV
                     IQPQGTPCDDPVETTPQGPAPTPDLRPEGGETPPR"
     misc_feature    complement(272026..273024)
                     /locus_tag="BCG_0241c"
                     /note="Predicted integral membrane protein [Function
                     unknown]; Region: COG0392"
                     /db_xref="CDD:223469"
     gene            273287..274390
                     /locus_tag="BCG_0242"
                     /db_xref="GeneID:4697022"
     CDS             273287..274390
                     /locus_tag="BCG_0242"
                     /note="Differs from Rv0205 by 1aa, R72H"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_976340.1"
                     /db_xref="GI:121636117"
                     /db_xref="GeneID:4697022"
                     /translation="MSASLDDASVAPLVRKTAAWAWRFLVILAAMVALLWVLNKFEVI
                     VVPVLLALMLSALLVPPVDWLDSRGLPRAVAVTLVLLSGFAVLGGILTFVVSQFIAGL
                     PHLVTEVERSIDSARRWLIEGPAHLRGEQIDNAGNAAIEALRNNQAKLTSGALSTAAT
                     ITELVTAAVLVLFTLIFFLYGGRSIWQYVTKAFPASVRDRVRAAGRAGYASLIGYARA
                     TFLVALTDAAGVGAGLAVMGVPLALPLASLVFFGAFIPLIGAVVAGFLAVVVALLAKG
                     IGYALITVGLLIAVNQLEAHLLQPLVMGRAVSIHPLAVVLAIAAGGVLAGVVGALLAV
                     PTAAFFNNAVQVLLGGNPFADVADVSSDHLTEV"
     misc_feature    273347..274330
                     /locus_tag="BCG_0242"
                     /note="Domain of unknown function DUF20; Region: UPF0118;
                     pfam01594"
                     /db_xref="CDD:250730"
     gene            complement(274387..277221)
                     /gene="mmpL3"
                     /locus_tag="BCG_0243c"
                     /db_xref="GeneID:4697222"
     CDS             complement(274387..277221)
                     /gene="mmpL3"
                     /locus_tag="BCG_0243c"
                     /note="Differs from Rv0206c by 2aa, I384F, E466D"
                     /codon_start=1
                     /transl_table=11
                     /product="transmembrane transport protein mmpL3"
                     /protein_id="YP_976341.1"
                     /db_xref="GI:121636118"
                     /db_xref="GeneID:4697222"
                     /translation="MFAWWGRTVYRYRFIVIGVMVALCLGGGVFGLSLGKHVTQSGFY
                     DDGSQSVQASVLGDQVYGRDRSGHIVAIFQAPAGKTVDDPAWSKKVVDELNRFQQDHP
                     DQVLGWAGYLRASQATGMATADKKYTFVSIPLKGDDDDTILNNYKAIAPDLQRLDGGT
                     VKLAGLQPVAEALTGTIATDQRRMEVLALPLVAVVLFFVFGGVIAAGLPVMVGGLCIA
                     GALGIMRFLAIFGPVHYFAQPVVSLIGLGIAIDYGLFIVSRFREEIAEGYDTETAVRR
                     TVITAGRTVTFSAVLIVASAIGLLLFPQGFLKSLTYATIASVMLSAILSITVLPACLG
                     ILGKHVDALGVRTLFRVPFLANWKISAAYLNWLADRLQRTKTREEVEAGIWGKLVNRV
                     MKRPVLFAAPIVIIMILLIIPVGKLSLGGISEKYLPPTNSVRQAQEEFDKLFPGYRTN
                     PLTLVIQTSNHQPVTEAQIADIRSKAMAIGGFIEPDNDPANMWQERAYAVGASKDPSV
                     RVLQNGLINPADASKKLTELRAITPPKGITVLVGGTPALELDSIHGLFAKMPLMVVIL
                     LTTTIVLMFLAFGSVVLPIKATLMSALTLGSTMGILTWIFVDGHFSKWLNFTPTPLTA
                     PVIGLIIALVFGLSTDYEVFLVSRMVEARERGMSTQEAIRIGTAATGRIITAAALIVA
                     VVAGAFVFSDLVMMKYLAFGLMAALLLDATVVRMFLVPSVMKLLGDDCWWAPRWARRL
                     QTRIGLGEIHLPDERKRPVSNGRPARPPVTAGLVAARAAGDPRPPHDPTHPLAESPRP
                     ARSSPASSPELTPALEATAAPAAPSGASTTRMQIGSSTEPPTTRLAAAGRSVQSPAST
                     PPPTPTPPSAPSAGQTRAMPLAANRSTDAAGDPAEPTAALPIIRSDGDDSEAATEQLN
                     ARGTSDKTRQRRRGGGALSAQDLLRREGRL"
     misc_feature    complement(275065..277221)
                     /gene="mmpL3"
                     /locus_tag="BCG_0243c"
                     /note="Predicted exporters of the RND superfamily [General
                     function prediction only]; Region: COG1033"
                     /db_xref="CDD:223964"
     misc_feature    complement(276208..277089)
                     /gene="mmpL3"
                     /locus_tag="BCG_0243c"
                     /note="MMPL family; Region: MMPL; cl21543"
                     /db_xref="CDD:271963"
     misc_feature    complement(274990..275946)
                     /gene="mmpL3"
                     /locus_tag="BCG_0243c"
                     /note="MMPL family; Region: MMPL; cl21543"
                     /db_xref="CDD:271963"
     gene            complement(277287..278015)
                     /locus_tag="BCG_0244c"
                     /db_xref="GeneID:4695521"
     CDS             complement(277287..278015)
                     /locus_tag="BCG_0244c"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_976342.1"
                     /db_xref="GI:121636119"
                     /db_xref="GeneID:4695521"
                     /translation="MSLTEDVTSQTSESLARHSVLAEDLSQDGLTSLGAPGARVLLVW
                     DAPNLDMGLGSILGRRPTALERPRFDALGRWLLARTAEIVAGRPGISTEPEATVFTNI
                     APGSAEVVRPWVDALRNVGFAVFAKPKVDEDSDVDRDMLAHIDERYREGLAALVVASA
                     DGQAFRQPLEAVARSGTPVQVLGFREHASWALASDTLEFVDLEDIAGVFREPLPRIGL
                     DSLPEQGAWLQPFRPLSSLLTSRV"
     misc_feature    complement(277413..277898)
                     /locus_tag="BCG_0244c"
                     /note="LabA_like proteins; Region: LabA_like; cd06167"
                     /db_xref="CDD:199895"
     misc_feature    complement(order(277527..277529,277533..277535,
                     277539..277541,277605..277607,277872..277874,
                     277881..277883))
                     /locus_tag="BCG_0244c"
                     /note="putative metal binding site [ion binding]; other
                     site"
                     /db_xref="CDD:199895"
     gene            complement(278018..278809)
                     /gene="trmB"
                     /locus_tag="BCG_0245c"
                     /gene_synonym="yggH"
                     /db_xref="GeneID:4697253"
     CDS             complement(278018..278809)
                     /gene="trmB"
                     /locus_tag="BCG_0245c"
                     /gene_synonym="yggH"
                     /EC_number="2.1.1.33"
                     /note="tRNA (guanine-N(7)-)-methyltransferase; catalyzes
                     the formation of N(7)-methylguanine at position 46 (m7G46)
                     in tRNA by transferring the methyl residue from
                     S-adenosyl-L-methionine"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (guanine-N(7)-)-methyltransferase"
                     /protein_id="YP_976343.1"
                     /db_xref="GI:121636120"
                     /db_xref="GeneID:4697253"
                     /translation="MVHHGQMHAQPGVGLRPDTPVASGQLPSTSIRSRRSGISKAQRE
                     TWERLWPELGLLALPQSPRGTPVDTRAWFGRDAPVVLEIGSGSGTSTLAMAKAEPHVD
                     VIAVDVYRRGLAQLLCAIDKVGSDGINIRLILGNAVDVLQHLIAPDSLCGVRVFFPDP
                     WPKARHHKRRLLQPATMALIADRLVPSGVLHAATDHPGYAEHIAAAGDAEPRLVRVDP
                     DTELLPISVVRPATKYERKAQLGGGAVIELLWKKHGCSERDLKIR"
     misc_feature    complement(278240..278572)
                     /gene="trmB"
                     /locus_tag="BCG_0245c"
                     /gene_synonym="yggH"
                     /note="S-adenosylmethionine-dependent methyltransferases
                     (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes
                     that use S-adenosyl-L-methionine (SAM or AdoMet) as a
                     substrate for methyltransfer, creating the product
                     S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases;
                     cd02440"
                     /db_xref="CDD:100107"
     misc_feature    complement(order(278336..278338,278399..278407,
                     278486..278491,278543..278563))
                     /gene="trmB"
                     /locus_tag="BCG_0245c"
                     /gene_synonym="yggH"
                     /note="S-adenosylmethionine binding site [chemical
                     binding]; other site"
                     /db_xref="CDD:100107"
     gene            278941..280026
                     /locus_tag="BCG_0246"
                     /db_xref="GeneID:4697234"
     CDS             278941..280026
                     /locus_tag="BCG_0246"
                     /note="Differs from Rv0209 by 1aa, A162V"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_976344.1"
                     /db_xref="GI:121636121"
                     /db_xref="GeneID:4697234"
                     /translation="MRGQGHQIFVDELARFATSSADQRVVAIAQRAAEPLRVAVRGRP
                     GVGCRTVARALQGAGSSSGMTVTPQARAADSDVDLVVYVTVEVVKPEDREAIAATRRP
                     VVAVLNKADLAGPLSGAGPIVMAQARCAQFSTLLGVPMESMIGLLAVAALDDLDDTLR
                     AALRALAAHPDGFDALDRAVAGFLAAALPVPTEVRLRLLDTLDLFGIALGMAAFRPGR
                     PSRTPAQLRTLLRRVSGVDAVIDKVTAAGSEVRYRRLLDAVAELEALAAQAKEIGGPI
                     GEFLRDDDTVLARMAAAVDVALAVGLDVGPLDDPAAHLPRAVRWHRYSLDNGDMHRTC
                     GADIARGSLRLWSLAGGMPLHRYRKSS"
     gene            280023..281501
                     /locus_tag="BCG_0247"
                     /db_xref="GeneID:4699331"
     CDS             280023..281501
                     /locus_tag="BCG_0247"
                     /note="Differs from Rv0210 by 1aa, T486A"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_976345.1"
                     /db_xref="GI:121636122"
                     /db_xref="GeneID:4699331"
                     /translation="MIRAASDDPAGVDELVAAIAPGLAGLGLPVINRREVVLVTGPWL
                     AGVSGVRAALAERLPQRRFVETAELGPGDAPVAVVFVVSAATALTESDCVLLDTAAEH
                     TDAVVAVVSKIDVHRGWRDVLTSNRDRLAARASRYARVPWVGAAAAPELGEPYLDDLV
                     AAIQKQLADPAVARRNMLRAWESRLLMVARRFDGDAQSAGRRARVDALRQQRRTVLRQ
                     GRQSKSEHTIALRAQIQHARVKLSYFARNRCSLLRVELQEHVAGLSRKDIARFAAYTR
                     GRVQEVVAEVGEGAVAHLADVAQLLGVPVQPPVLENLPAVLPTVVAPPLTSRRLEIRL
                     TTLLGAGFGLGIALTLSRLVAGLTPGLAASGMVAGVAIGLAVTAWVVNARALLHDRVV
                     VDRWTGEVTASLRSVVEQLVATRVVAVETLLSTAISERDDAENARVADQVSIIDGELR
                     EHAVAAARAAALRDREMPAVRAALEAVRAELGEPGTPTTGLF"
     gene            281685..283505
                     /gene="pckA"
                     /locus_tag="BCG_0248"
                     /db_xref="GeneID:4697998"
     CDS             281685..283505
                     /gene="pckA"
                     /locus_tag="BCG_0248"
                     /EC_number="4.1.1.32"
                     /standard_name="pckG; pck1"
                     /note="catalyzes the phosphorylation and decarboxylation
                     of oxaloacetate to form phosphoenolpyruvate using GTP"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoenolpyruvate carboxykinase"
                     /protein_id="YP_976346.1"
                     /db_xref="GI:121636123"
                     /db_xref="GeneID:4697998"
                     /translation="MTSATIPGLDTAPTNHQGLLSWVEEVAELTQPDRVVFTDGSEEE
                     FQRLCDQLVEAGTFIRLNPEKHKNSYLALSDPSDVARVESRTYICSAKEIDAGPTNNW
                     MDPGEMRSIMKDLYRGCMRGRTMYVVPFCMGPLGAEDPKLGVEITDSEYVVVSMRTMT
                     RMGKAALEKMGDDGFFVKALHSVGAPLEPGQKDVAWPCSETKYITHFPETREIWSYGS
                     GYGGNALLGKKCYSLRIASAMAHDEGWLAEHMLILKLISPENKAYYFAAAFPSACGKT
                     NLAMLQPTIPGWRAETLGDDIAWMRFGKDGRLYAVNPEFGFFGVAPGTNWKSNPNAMR
                     TIAAGNTVFTNVALTDDGDVWWEGLEGDPQHLIDWKGNDWYFRETETNAAHPNSRYCT
                     PMSQCPILAPEWDDPQGVPISGILFGGRRKTTVPLVTEARDWQHGVFIGATLGSEQTA
                     AAEGKVGNVRRDPMAMLPFLGYNVGDYFQHWINLGKHADESKLPKVFFVNWFRRGDDG
                     RFLWPGFGENSRVLKWIVDRIEHKAGGATTPIGTVPAVEDLDLDGLDVDAADVAAALA
                     VDADEWRQELPLIEEWLQFVGEKLPTGVKDEFDALKERLG"
     misc_feature    281739..283487
                     /gene="pckA"
                     /locus_tag="BCG_0248"
                     /note="Phosphoenolpyruvate carboxykinase (PEPCK), a
                     critical gluconeogenic enzyme, catalyzes the first
                     committed step in the diversion of tricarboxylic acid
                     cycle intermediates toward gluconeogenesis. It catalyzes
                     the reversible decarboxylation and...; Region: PEPCK_GTP;
                     cd00819"
                     /db_xref="CDD:238417"
     misc_feature    order(281925..281927,282342..282344,282348..282350,
                     282366..282371,282429..282431,282495..282515,
                     282567..282572,282636..282638,282642..282644,
                     282669..282671,282849..282851,283218..283220,
                     283227..283229,283236..283238)
                     /gene="pckA"
                     /locus_tag="BCG_0248"
                     /note="active site"
                     /db_xref="CDD:238417"
     misc_feature    order(281925..281927,282342..282344,282348..282350,
                     282366..282371,282636..282638,282849..282851)
                     /gene="pckA"
                     /locus_tag="BCG_0248"
                     /note="substrate-binding site [chemical binding]; other
                     site"
                     /db_xref="CDD:238417"
     misc_feature    order(282369..282371,282429..282431,282510..282512,
                     282567..282572,282636..282638)
                     /gene="pckA"
                     /locus_tag="BCG_0248"
                     /note="metal-binding site [ion binding]"
                     /db_xref="CDD:238417"
     misc_feature    order(282498..282500,282504..282506,282942..282944,
                     283185..283190,283218..283220,283227..283229,
                     283236..283238)
                     /gene="pckA"
                     /locus_tag="BCG_0248"
                     /note="GTP binding site [chemical binding]; other site"
                     /db_xref="CDD:238417"
     gene            complement(283572..284543)
                     /gene="nadR"
                     /locus_tag="BCG_0249c"
                     /db_xref="GeneID:4698418"
     CDS             complement(283572..284543)
                     /gene="nadR"
                     /locus_tag="BCG_0249c"
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator NadR"
                     /protein_id="YP_976347.1"
                     /db_xref="GI:121636124"
                     /db_xref="GeneID:4698418"
                     /translation="MTHGMVLGKFMPPHAGHVYLCEFARRWVDELTIVVGSTAAEPIP
                     GAQRVAWMRELFPFDRVVHLANENPQRPWEHPDFWDIWKASLQGVLATRPDFVFGAEP
                     YNADFAQVLGARFVAVDHGRTVVPVTATDIRADPLGHWQHIPRCVRPAFVKRVSIIGP
                     ESTGKTTLAQAVAEKLRTKWVPERAKMLRELNGGSLIGLEWAEIVRGQIASEEALARD
                     ADRVLICDTDPLATTVWAEFLAGGCPQELRDLARRPYDLTLLTTPDVPWDADDGRCVP
                     GARGTFFARCEQALRAAGRSFVVITGGWEERLSVSLRAVEELVRARR"
     misc_feature    complement(283620..284543)
                     /gene="nadR"
                     /locus_tag="BCG_0249c"
                     /note="nicotinamide-nucleotide adenylyltransferase, NadR
                     type; Region: nadR_NMN_Atrans; TIGR01526"
                     /db_xref="CDD:233448"
     misc_feature    complement(284100..284537)
                     /gene="nadR"
                     /locus_tag="BCG_0249c"
                     /note="Nicotinamide/nicotinate mononucleotide
                     adenylyltransferase of bifunctional NadR-like proteins;
                     Region: NMNAT_NadR; cd02167"
                     /db_xref="CDD:173918"
     misc_feature    complement(order(284163..284165,284169..284171,
                     284241..284249,284298..284300,284307..284315,
                     284319..284330,284343..284345,284421..284423,
                     284436..284438,284484..284486,284493..284495,
                     284502..284504,284514..284525))
                     /gene="nadR"
                     /locus_tag="BCG_0249c"
                     /note="active site"
                     /db_xref="CDD:173918"
     misc_feature    complement(284493..284504)
                     /gene="nadR"
                     /locus_tag="BCG_0249c"
                     /note="(T/H)XGH motif; other site"
                     /db_xref="CDD:173918"
     misc_feature    complement(283575..284111)
                     /gene="nadR"
                     /locus_tag="BCG_0249c"
                     /note="Predicted ATPase/kinase involved in NAD metabolism
                     [Coenzyme metabolism]; Region: NadR; COG3172"
                     /db_xref="CDD:225713"
     gene            complement(284540..285853)
                     /locus_tag="BCG_0250c"
                     /db_xref="GeneID:4696616"
     CDS             complement(284540..285853)
                     /locus_tag="BCG_0250c"
                     /EC_number="2.1.1.-"
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase"
                     /protein_id="YP_976348.1"
                     /db_xref="GI:121636125"
                     /db_xref="GeneID:4696616"
                     /translation="MSIKAYAKTQGIAVTSVNGLVAGHGSVQETWLAMQSAAALSGTP
                     RLVGFSCIDTFPEVLWLAQRARQAWDGVRIVIGNAMATLNYERILRQHDCFDYVVVGD
                     GEVAFTKLALALANDAAVDDVPGLARRSEQGQILRTPSSLVDLDELPRPARDELPTVL
                     ADGFAASVFSTRGCPYRCTFCGTGAMSAMLGKDSYRAKSVDAVVDEIDYLVSDYDVNF
                     LSITDDLFISKHPGSQQRAADFANAVLRRGISVNFMVDIRLDSVVDLDLFKHLHRAGL
                     RRVFIGVETGSYEQLRAYRKQILTRGQDAADTINALQQLGIDVIPGTIMFHPTVQPDE
                     LRETVRLLRATKYTVGFKFMSRIVPYPGTPLYQAYSDAGYLTAKWPLGQWEFVDPEAS
                     RVYADVVAKVAPDVGISFDEAEAYFLSRLDEWENVIAGRIAEATS"
     misc_feature    complement(285461..285775)
                     /locus_tag="BCG_0250c"
                     /note="B12 binding domain_like associated with radical SAM
                     domain. This domain shows similarity with B12
                     (adenosylcobamide) binding domains found in several
                     enzymes, such as glutamate mutase, methionine synthase and
                     methylmalonyl-CoA mutase, but it lacks the...; Region:
                     radical_SAM_B12_BD; cd02068"
                     /db_xref="CDD:239019"
     misc_feature    complement(284828..285352)
                     /locus_tag="BCG_0250c"
                     /note="Radical SAM superfamily; Region: Radical_SAM;
                     pfam04055"
                     /db_xref="CDD:252342"
     misc_feature    complement(284732..285343)
                     /locus_tag="BCG_0250c"
                     /note="Radical SAM superfamily. Enzymes of this family
                     generate radicals by combining a 4Fe-4S cluster and
                     S-adenosylmethionine (SAM) in close proximity. They are
                     characterized by a conserved CxxxCxxC motif, which
                     coordinates the conserved iron-sulfur cluster; Region:
                     Radical_SAM; cd01335"
                     /db_xref="CDD:100105"
     misc_feature    complement(order(284783..284788,284882..284884,
                     285008..285010,285098..285106,285182..285187,
                     285191..285193,285308..285316,285320..285322,
                     285326..285328,285332..285334))
                     /locus_tag="BCG_0250c"
                     /note="FeS/SAM binding site; other site"
                     /db_xref="CDD:100105"
     gene            285967..287580
                     /gene="fadD4"
                     /locus_tag="BCG_0251"
                     /db_xref="GeneID:4697727"
     CDS             285967..287580
                     /gene="fadD4"
                     /locus_tag="BCG_0251"
                     /EC_number="2.3.1.86"
                     /note="activates fatty acids by binding to coenzyme A"
                     /codon_start=1
                     /transl_table=11
                     /product="long-chain-fatty-acid--CoA ligase"
                     /protein_id="YP_976349.1"
                     /db_xref="GI:121636126"
                     /db_xref="GeneID:4697727"
                     /translation="MPRGELYKRFRLVMGGIAPCGSGRRAATYPRRMQIRPYIAADKP
                     AVILYPSGTVISFDELEARANRLAHWFRQAGLREDDVVAILMENNEHVHAVMWAARRS
                     GLYYVPINTHLTASEAAYIVDNSGAKAIVGSAALRETCHGLAEHLPGGLPDLLMLAGG
                     GLVGWMTYPECVADQPDTPIEDEREGDLLQYSSGTTGRPKGIKRELPHVSPDAAPGMM
                     PALLDFWMDADSVYLSPAPMYHTAPSVWTMSALAAGVTTVVMEKFDAEGALDAIQRYR
                     VTHAQFVPAMFVRMLKLPEAVRNSYDMSSLRRVIHAAAPCPVQIKEQMIHWWGPIIDE
                     YYASSEASGSTLITAEDWLTHPGSVGKPIQGGVHIVGADGSELPPNQPGEIYFEGGYP
                     FEYLNDPAKTAASRNKHGWVTVGDVGYLDDDGYLFLTGRRHHMIISGGVNIYPQEAEN
                     LLVAHPKVLDAAVFGVPDDEMGQRVMAAVQTVDSADANDQFAGELLAWLRDRLSHFKC
                     PRSIAFEPQLPRTDTGKLYKSGLVEKYSV"
     misc_feature    286096..287571
                     /gene="fadD4"
                     /locus_tag="BCG_0251"
                     /note="long-chain-fatty-acid--CoA ligase; Validated;
                     Region: PRK08276"
                     /db_xref="CDD:236215"
     misc_feature    286528..287559
                     /gene="fadD4"
                     /locus_tag="BCG_0251"
                     /note="Bacterial Bile acid CoA ligases and similar
                     proteins; Region: BACL_like; cd05929"
                     /db_xref="CDD:213295"
     misc_feature    order(286531..286533,286540..286557,286561..286566)
                     /gene="fadD4"
                     /locus_tag="BCG_0251"
                     /note="acyl-activating enzyme (AAE) consensus motif; other
                     site"
                     /db_xref="CDD:213295"
     misc_feature    order(286540..286542,286900..286905,286966..286983,
                     287212..287214,287248..287250,287257..287259,
                     287290..287292,287539..287541)
                     /gene="fadD4"
                     /locus_tag="BCG_0251"
                     /note="putative AMP binding site [chemical binding]; other
                     site"
                     /db_xref="CDD:213295"
     misc_feature    order(286540..286542,286672..286677,286813..286815,
                     286819..286824,286831..286833,286900..286905,
                     286966..286983,287212..287214,287248..287250,
                     287257..287259,287281..287292,287482..287484)
                     /gene="fadD4"
                     /locus_tag="BCG_0251"
                     /note="putative active site [active]"
                     /db_xref="CDD:213295"
     misc_feature    order(286672..286674,286819..286824,286831..286833,
                     286900..286902,287281..287289,287464..287466,
                     287482..287484)
                     /gene="fadD4"
                     /locus_tag="BCG_0251"
                     /note="putative CoA binding site [chemical binding]; other
                     site"
                     /db_xref="CDD:213295"
     gene            complement(287622..288788)
                     /gene="fadE3"
                     /locus_tag="BCG_0252c"
                     /db_xref="GeneID:4696271"
     CDS             complement(287622..288788)
                     /gene="fadE3"
                     /locus_tag="BCG_0252c"
                     /EC_number="1.3.99.-"
                     /note="In Mycobacterium bovis BCG Pasteur, and
                     Mycobacterium bovis, a 29 bp insertion leads to a longer
                     product compared to its homolog in Mycobacterium
                     tuberculosis strain H37Rv (388 aa versus 357 aa). Differs
                     from Mb0221c by 1aa, S361A"
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-CoA dehydrogenase fadE3"
                     /protein_id="YP_976350.1"
                     /db_xref="GI:121636127"
                     /db_xref="GeneID:4696271"
                     /translation="MRNELNDDEAMLVATVRAFIDRDVKPTVREVEHANSYPEAWIEQ
                     MKHIGIYGLAIDEQYGGSPVSMPCYVQVTQELARGWMSLAGAMGGHTVVAKLLTLFGT
                     EEQRRTYLPPMASGELRATMALTEPGGGSDLQNMSTTALADGPEGSAGLLINGCKTWI
                     SNARRSGLFAVLCKTDPNATPRHQGMSIVLVEPGPGLTVSRDLPKLGYKGVESCELSF
                     DNLRVPVSAILGGAMGQGFSQMMKGLETGRIQVAARALGVATAALEDSLAYAQQRESF
                     GRPIWQHQAVGNYLADMATKLTAARQLTRYAAERYDSGQRCDMEAGMAKLFASEVAME
                     IALNAVRIHGGYGYSTEYDVERYFRDSPLMILGEGTNEIQRNVIAGQLVARGGI"
     misc_feature    complement(287634..288788)
                     /gene="fadE3"
                     /locus_tag="BCG_0252c"
                     /note="Acyl-CoA dehydrogenases [Lipid metabolism]; Region:
                     CaiA; COG1960"
                     /db_xref="CDD:224871"
     misc_feature    complement(287643..288770)
                     /gene="fadE3"
                     /locus_tag="BCG_0252c"
                     /note="Acyl-CoA dehydrogenase; Region: ACAD; cl09933"
                     /db_xref="CDD:263927"
     misc_feature    complement(order(287673..287675,287679..287681,
                     287685..287693,288306..288308,288312..288314,
                     288417..288419,288423..288425,288513..288515))
                     /gene="fadE3"
                     /locus_tag="BCG_0252c"
                     /note="active site"
                     /db_xref="CDD:173838"
     gene            288845..289858
                     /locus_tag="BCG_0253"
                     /db_xref="GeneID:4697579"
     CDS             288845..289858
                     /locus_tag="BCG_0253"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_976351.1"
                     /db_xref="GI:121636128"
                     /db_xref="GeneID:4697579"
                     /translation="MASGYGGIRVGGPYFDDLSKGQVFDWAPGVTLSLGLAAAHQSIV
                     GNRLRLALDSDLCAAVTGMPGPLAHPGLVCDVAIGQSTLATQRVKANLFYRGLRFHRF
                     PAVGDTLYTRTEVVGLRANSPKPGRAPTGLAGLRMTTIDRTDRLVLDFYRCAMLPASP
                     DWKPGAVPGDDLSRIGADAPAPAADPTAHWDGAVFRKRVPGPHFDAGIAGAVLHSTAD
                     LVSGAPELARLTLNIAATHHDWRVSGRRLVYGGHTIGLALAQATRLLPNLATVLDWES
                     CDHTAPVHEGDTLYSELHIESAQAHADGGVLGLRSLVYAVSDSASEPDRQVLDWRFSA
                     LQF"
     misc_feature    288878..289324
                     /locus_tag="BCG_0253"
                     /note="FkbR2 is a Streptomyces hygroscopicus protein with
                     a hot dog fold that belongs to a conserved family of
                     proteins found in prokaryotes and archaea but not in
                     eukaryotes. FkbR2  has sequence similarity to (R)-specific
                     enoyl-CoA hydratase, the peroxisomal...; Region: FkbR2;
                     cd03451"
                     /db_xref="CDD:239535"
     misc_feature    order(288965..288967,288980..288982,288986..288988,
                     288995..288997,289043..289045,289052..289057)
                     /locus_tag="BCG_0253"
                     /note="putative active site [active]"
                     /db_xref="CDD:239535"
     misc_feature    order(288980..288982,288986..288988,288995..288997,
                     289052..289054)
                     /locus_tag="BCG_0253"
                     /note="putative catalytic site [active]"
                     /db_xref="CDD:239535"
     misc_feature    289418..289849
                     /locus_tag="BCG_0253"
                     /note="The hotdog fold was initially identified in the E.
                     coli FabA (beta-hydroxydecanoyl-acyl carrier protein
                     (ACP)-dehydratase) structure and subsequently in 4HBT
                     (4-hydroxybenzoyl-CoA thioesterase) from Pseudomonas. A
                     number of other seemingly unrelated...; Region: hot_dog;
                     cl00509"
                     /db_xref="CDD:271497"
     misc_feature    order(289589..289594,289679..289690)
                     /locus_tag="BCG_0253"
                     /note="active site 2 [active]"
                     /db_xref="CDD:239524"
     misc_feature    order(289607..289609,289616..289621,289628..289630,
                     289655..289663)
                     /locus_tag="BCG_0253"
                     /note="active site 1 [active]"
                     /db_xref="CDD:239524"
     gene            complement(289855..290763)
                     /gene="lipW"
                     /locus_tag="BCG_0254c"
                     /db_xref="GeneID:4698090"
     CDS             complement(289855..290763)
                     /gene="lipW"
                     /locus_tag="BCG_0254c"
                     /EC_number="3.1.1.-"
                     /note="Differs from Rv0217c by 1aa T184P"
                     /codon_start=1
                     /transl_table=11
                     /product="esterase lipW"
                     /protein_id="YP_976352.1"
                     /db_xref="GI:121636129"
                     /db_xref="GeneID:4698090"
                     /translation="MSGNEVHPDLRRIAVVTPRQLVGPRTLPVMRALIVVAGLRMSRT
                     PPDIEVLTLESGVGVRLYRPAGSNEPAPALLWIHAGGYVMGTAQQDDRLCLRFSSRLG
                     ITVASVDYRLAPENPYPAALGDCYSALTWLASLPAVDPARVAIGGASAGGGLAAALAL
                     LARDRGGITPAFQLLVYPMLDDRTSIAPANPHYRLWNGRANRFGWRAYLGDADARVAV
                     PGRRDDLGGLAPAWIGVGTHDLLHDEDLAYAERLTAAGVPCQVEVVEGAFHGFDRVAP
                     NVGVSQRFFTSQCNSLRAALALSNRT"
     misc_feature    complement(289900..290625)
                     /gene="lipW"
                     /locus_tag="BCG_0254c"
                     /note="Esterases and lipases (includes fungal lipases,
                     cholinesterases, etc.)  These enzymes act on carboxylic
                     esters (EC: 3.1.1.-). The catalytic apparatus involves
                     three residues (catalytic triad): a serine, a glutamate or
                     aspartate and a histidine.These...; Region:
                     Esterase_lipase; cl21494"
                     /db_xref="CDD:271914"
     misc_feature    complement(289951..290544)
                     /gene="lipW"
                     /locus_tag="BCG_0254c"
                     /note="alpha/beta hydrolase fold; Region: Abhydrolase_3;
                     pfam07859"
                     /db_xref="CDD:254474"
     gene            290856..292184
                     /locus_tag="BCG_0255"
                     /db_xref="GeneID:4695784"
     CDS             290856..292184
                     /locus_tag="BCG_0255"
                     /note="Differs from Rv0218 by 2aa, R316C, N413D"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_976353.1"
                     /db_xref="GI:121636130"
                     /db_xref="GeneID:4695784"
                     /translation="MSDPARGAEAEDAYGFPAGLWRWLQRHPPPALHRLTRFRSPLRG
                     PWLTSVFGLVLLVALPFVIITGLLSYIAYAPQLGQAIPGDVGWLRLPAFTWPTRPSWL
                     YRLTQGLHVGLGLVIIPVVLAKLWSVIPRLFVWPPARSIAQVLERLSVLMLVGGILFQ
                     IVTGVLNIQYDYIFGFSFYTGHYFGAWVFIAGFLLHIVVKIPHMVTGLRSIPMREVLG
                     TNVADTRAQPCDPDGLVSVNPGEATLSRRGALGLVGAGVLLIGVLTVGQTLGGFTRKA
                     ALLLPRGRVVSPGDFPVNKTAAAAGITAEAIGPDWRLVLRGGPAEVVLDRATLAGLPQ
                     RTARLPLACVEGWSAVRTWSGVPLAELALLAGVPAARSARVTSLQRGGAFGEAKLAAN
                     QIADPDALLALRVDGADLSLNHGYPARIIVPALPGVHNTKWVAGIEFHKR"
     misc_feature    290988..292028
                     /locus_tag="BCG_0255"
                     /note="Sulfite oxidase and related enzymes [General
                     function prediction only]; Region: COG2041"
                     /db_xref="CDD:224952"
     misc_feature    291783..292181
                     /locus_tag="BCG_0255"
                     /note="Sulfite oxidase (SO) family, molybdopterin binding
                     domain. This molybdopterin cofactor (Moco) binding domain
                     is found in a variety of oxidoreductases, main members of
                     this family are nitrate reductase (NR) and sulfite oxidase
                     (SO). SO catalyzes the...; Region: SO_family_Moco;
                     cd00321"
                     /db_xref="CDD:238198"
     misc_feature    order(291882..291884,292005..292007,292095..292097,
                     292110..292112,292134..292136,292143..292145,
                     292149..292154)
                     /locus_tag="BCG_0255"
                     /note="Moco binding site; other site"
                     /db_xref="CDD:238198"
     misc_feature    291882..291884
                     /locus_tag="BCG_0255"
                     /note="metal coordination site [ion binding]; other site"
                     /db_xref="CDD:238198"
     gene            292186..292734
                     /locus_tag="BCG_0256"
                     /db_xref="GeneID:4697761"
     CDS             292186..292734
                     /locus_tag="BCG_0256"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_976354.1"
                     /db_xref="GI:121636131"
                     /db_xref="GeneID:4697761"
                     /translation="MFDIATRFKNSYGSGPLHLLAMVSGFALLGYIVATARPSALWNQ
                     ATWWQSIAVWFVAAVVAHDLLLYPLYALADRILARLVGRRDVSAPRRRPELPVRNYIR
                     IPALAAGLTLLVFLPGIIRQGAPTYLDATGQTQEPFLGRWLLLTAVAFGISAAAYAIR
                     LVVAHVRRRRAGCSRVDAIDEE"
     gene            292744..293985
                     /gene="lipC"
                     /locus_tag="BCG_0257"
                     /db_xref="GeneID:4699256"
     CDS             292744..293985
                     /gene="lipC"
                     /locus_tag="BCG_0257"
                     /EC_number="3.1.1.-"
                     /codon_start=1
                     /transl_table=11
                     /product="esterase lipC"
                     /protein_id="YP_976355.1"
                     /db_xref="GI:121636132"
                     /db_xref="GeneID:4699256"
                     /translation="MNQRRAAGSTGVAYIRWLLRARPADYMLALSVAGGSLPVVGKHL
                     KPLGGVTAIGVWGARHASDFLSATAKDLLTPGINEVRRRDRASTQEVSVAALRGIVSP
                     DDLAVEWPAPERTPPVCGALRHRRYVHRRRVLYGDDPAQLLDVWRRKDMPTKPAPVLI
                     FVPGGAWVHGSRAIQGYAVLSRLAAQGWVCLSIDYRVAPHHRWPRHILDVKTAIAWAR
                     ANVDKFGGDRNFIAVAGCSAGGHLSALAGLTANDPQYQAELPEGSDTSVDAVVGIYGR
                     YDWEDRSTPERARFVDFLERVVVQRTIDRHPEVFRDASPIQRVTRNAPPFLVIHGSRD
                     CVIPVEQARSFVERLRAVSRSQVGYLELPGAGHGFDLLDGARTGPTAHAIALFLNQVH
                     RSRAQFAKEVIQTPANCMVAL"
     misc_feature    293218..293856
                     /gene="lipC"
                     /locus_tag="BCG_0257"
                     /note="alpha/beta hydrolase fold; Region: Abhydrolase_3;
                     pfam07859"
                     /db_xref="CDD:254474"
     misc_feature    293290..293850
                     /gene="lipC"
                     /locus_tag="BCG_0257"
                     /note="Prolyl oligopeptidase family; Region: Peptidase_S9;
                     cl19144"
                     /db_xref="CDD:267497"
     gene            293999..294772
                     /locus_tag="BCG_0258"
                     /db_xref="GeneID:4698688"
     CDS             293999..294772
                     /locus_tag="BCG_0258"
                     /note="In Mycobacterium bovis and Mycobacterium bovis BCG
                     Pasteur, RD10, a 1902 bp deletion leads to a shorter
                     product with a different COOH part, compared to its
                     homolog in Mycobacterium tuberculosis strain H37Rv (257 aa
                     versus 469 aa). It also leads to the deletion of the next
                     protein, echA1 (Rv0222)"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_976356.1"
                     /db_xref="GI:121636133"
                     /db_xref="GeneID:4698688"
                     /translation="MKRLSGWDAVLLYSETPNVHMHTLKVAVIELDSDRQEFGVDAFR
                     EVIAGRLHKLEPLGYQLVDVPLKFHHPMWREHCQVDLNYHIRPWRLRAPGGRRELDEA
                     VGEIASTPLNRDHPLWEMYFVEGLANHRIAVVAKIHHALADGVASANMMARGMDLLPG
                     PEVGRYVPDPAPTKRQLLSAAFIDHLRHLGRIPATIRYTTQGLGRVRRSSRKLSPALT
                     MPFTPPPTFMNRIKKPLSKPSGRPPPHTNRAPSSMPLAM"
     misc_feature    294008..294688
                     /locus_tag="BCG_0258"
                     /note="Wax ester synthase-like Acyl-CoA acyltransferase
                     domain; Region: WES_acyltransf; pfam03007"
                     /db_xref="CDD:111851"
     gene            complement(294638..295447)
                     /locus_tag="BCG_0259c"
                     /db_xref="GeneID:4698049"
     CDS             complement(294638..295447)
                     /locus_tag="BCG_0259c"
                     /EC_number="1.2.1.-"
                     /note="In mycobacterium bovis strain AF2122/97 and
                     Mycobacterium bovis BCG Pasteur, RD10, a 1902 bp deletion,
                     compared to Mycobacterium tuberculosis H37Rv, truncates
                     Rv0221c and Rv0223c and removes Rv0222c;
                     In Mycobacterium bovis BCG Pasteur, a single base deletion
                     at position equivalent to Mycobacterium tuberculosis
                     H37Rv2 267419-267419(*-c) splits gene into two parts
                     compared to its homologs in Mycobacterium tuberculosis
                     strain H37Rv and Mycobacterium bovis AF2122/97 (116 aa and
                     269 aa, versus 487 aa and 385 aa, respectively. Also has
                     same 1 bp insertion, as Mycobacterium bovis AF2122/97, at
                     position equivalent to Mycobacterium tuberculosis H37Rv2
                     base 266743. Deletion in Mycobacterium bovis and bovis BCG
                     Pasteur of region RD10 leads to a different COOH part
                     compared to Mycobacterium tuberculosis strain H37Rv. May
                     be pseudogene"
                     /codon_start=1
                     /transl_table=11
                     /product="aldehyde dehydrogenase"
                     /protein_id="YP_976357.1"
                     /db_xref="GI:121636134"
                     /db_xref="GeneID:4698049"
                     /translation="MNYFAGAADKVTWTETRTGSYGQSIVSRESVGVVGAIVAWNVPL
                     FLAVNKIAPALLAGCTIVLKPAAETPLTANALAEVFAEVGLPEGVLSVVPGGIETGQA
                     LTSNPDIDMFTFTGSSAVGREVGRRAAEMLKPCTLELGGKSAAIILEDVDLAAAIPMM
                     VFSGVMNAGQGCVNQTRILAPRSRYDEIVAAVTNFVTALPVGPPSDPAAQIGPLISEK
                     QRTRVEALHRQGHRGGRSVGVRRRPSRGLGQRLLYPIHERRWRGKWHGQCG"
     misc_feature    complement(<294746..>295447)
                     /locus_tag="BCG_0259c"
                     /note="NAD(P)+-dependent aldehyde dehydrogenase
                     superfamily; Region: ALDH-SF; cl11961"
                     /db_xref="CDD:264488"
     misc_feature    complement(order(294932..294934,295028..295036,
                     295076..295081,295088..295090,295097..295108,
                     295247..295252,295256..295258,295301..295303,
                     295325..295339))
                     /locus_tag="BCG_0259c"
                     /note="NAD(P) binding site [chemical binding]; other site"
                     /db_xref="CDD:143395"
     misc_feature    complement(order(294932..294934,294941..294943,
                     295034..295036,295325..295327))
                     /locus_tag="BCG_0259c"
                     /note="catalytic residues [active]"
                     /db_xref="CDD:143395"
     misc_feature    294686..294687
                     /locus_tag="BCG_0258"
                     /note="RD10, 1902 bp. Region of Difference RD10, deleted
                     region in Mycobacterium bovis BCG Pasteur (position
                     294686..294687) and Mycobacterium bovis AF2122/97
                     (position 264979..264980) compared to Mycobacterium
                     tuberculosis H37Rv2 (position: 264755..266656, 1902bp).
                     Removes gene Rv0222 and truncates genes Rv0221 and Rv0223"
     gene            complement(295444..295794)
                     /locus_tag="BCG_0260c"
                     /db_xref="GeneID:4698185"
     CDS             complement(295444..295794)
                     /locus_tag="BCG_0260c"
                     /EC_number="1.2.1.-"
                     /note="In Mycobacterium bovis BCG Pasteur, a single base
                     deletion at position equivalent to Mycobacterium
                     tuberculosis H37Rv2 267419-267419(*-c) splits gene into
                     two parts compared to its homologs in Mycobacterium
                     tuberculosis strain H37Rv and Mycobacterium bovis
                     AF2122/97 (116 aa and 269 aa, versus 487 aa and 385 aa,
                     respectively. Also has same 1 bp insertion, as
                     Mycobacterium bovis AF2122/97, at position equivalent to
                     Mycobacterium tuberculosis H37Rv2 base 266743. May be
                     pseudogene"
                     /codon_start=1
                     /transl_table=11
                     /product="aldehyde dehydrogenase"
                     /protein_id="YP_976358.1"
                     /db_xref="GI:121636135"
                     /db_xref="GeneID:4698185"
                     /translation="MSDSATEYDKLFIGGKWTKPSTSDVIEVRCPATGEYVGKVPMAA
                     AADVDAAVAAARAAFDNGPWPSTPPHERAAVIAAAVKMLAERKDLFTKLLAAETGQPP
                     TIIETMHWMGSMGR"
     misc_feature    complement(<295450..295764)
                     /locus_tag="BCG_0260c"
                     /note="NAD(P)+-dependent aldehyde dehydrogenase
                     superfamily; Region: ALDH-SF; cl11961"
                     /db_xref="CDD:264488"
     gene            complement(295893..296657)
                     /locus_tag="BCG_0261c"
                     /db_xref="GeneID:4699063"
     CDS             complement(295893..296657)
                     /locus_tag="BCG_0261c"
                     /EC_number="2.1.1.-"
                     /note="Differs from Rv0224c by 1aa, L117F"
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase"
                     /protein_id="YP_976359.1"
                     /db_xref="GI:121636136"
                     /db_xref="GeneID:4699063"
                     /translation="MAVTDVFARRATLRRSLRLLADFRYEQRDPARFYRTLAADTAAM
                     IGDLWLATHSEPPVGRTLLDVGGGPGYFATAFSDAGVGYIGVEPDPDEMHAAGPAFTG
                     RPGMFVRASGMALPLADDSVDICLSSNVAEHVPRPWQLGTEMLRVTKPGGLVVLSYTV
                     WLGPFGGHEMGLSHYLGGARAAARYVRKHGHPAKNNYGSSLFAVSAAEGLRWAAGTGA
                     ALAVFPRYHPRWAWWLTSVPVLREFLVSNLVLVLTP"
     misc_feature    complement(296175..296477)
                     /locus_tag="BCG_0261c"
                     /note="S-adenosylmethionine-dependent methyltransferases
                     (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes
                     that use S-adenosyl-L-methionine (SAM or AdoMet) as a
                     substrate for methyltransfer, creating the product
                     S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases;
                     cd02440"
                     /db_xref="CDD:100107"
     misc_feature    complement(order(296274..296276,296322..296330,
                     296394..296399,296445..296465))
                     /locus_tag="BCG_0261c"
                     /note="S-adenosylmethionine binding site [chemical
                     binding]; other site"
                     /db_xref="CDD:100107"
     gene            296693..297847
                     /locus_tag="BCG_0262"
                     /db_xref="GeneID:4699029"
     CDS             296693..297847
                     /locus_tag="BCG_0262"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_976360.1"
                     /db_xref="GI:121636137"
                     /db_xref="GeneID:4699029"
                     /translation="MSALRSVLLLCWRDIGHPQGGGSEAYLQRIGAQLAASGIAVTLR
                     TARYPGAPRHELVDGVRISRAGGRYSVYLWALLAMAAARCGLGPLRRVRPDVVVDTQN
                     GWPFVARLLYGRRSLVLVHHCHREQWPVAGRMMGRLGWYVESMLSPRLHRRNQYVTVS
                     LPSARDLIALGVDSERIAVVRNGLDEAPSPTLSGPRAPTPRVVVLSRLVPHKQIEDAL
                     AAVAELQPRIPGLHLDIVGGGWWRQRLVDHVHRLDIADAVTFHGHVDDVTKHHVLQSS
                     WVHLLPSRKEGWGLAVIEAAQHGVPTIGYRSSGGLADSIVDGVTGILVDDRAELVAWL
                     EQLLSDSVLRDQLGAKAQARSGEFSWRQSAEALRSVLEAVQASRFVSGVV"
     misc_feature    296711..297808
                     /locus_tag="BCG_0262"
                     /note="This family is most closely related to the GT1
                     family of glycosyltransferases and named after YqgM in
                     Bacillus licheniformis about which little is known.
                     Glycosyltransferases catalyze the transfer of sugar
                     moieties from activated donor molecules to...; Region:
                     GT1_YqgM_like; cd03801"
                     /db_xref="CDD:99974"
     misc_feature    296717..297826
                     /locus_tag="BCG_0262"
                     /note="Glycosyltransferase [Cell envelope biogenesis,
                     outer membrane]; Region: RfaG; COG0438"
                     /db_xref="CDD:223515"
     gene            complement(297864..299594)
                     /locus_tag="BCG_0263c"
                     /db_xref="GeneID:4698239"
     CDS             complement(297864..299594)
                     /locus_tag="BCG_0263c"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_976361.1"
                     /db_xref="GI:121636138"
                     /db_xref="GeneID:4698239"
                     /translation="MRWFRPGYALVLVLLLAAPLLRPGYLLLRDAVSTPRSYVSANAL
                     GLTSAPRATPQDFAVALASHLVDGGVVVKALLLLGLWLAGWGAARLVATALPAAGAAG
                     QFVAITLAIWNPYVAERLLQGHWSLLVGYGCLPWVATAMLTMRTTVGAGWFGLFGLAF
                     WVALAGLTPSGLLLAATVAVVCVAMPGAGRPRWQCGVAALGSALVGALPWLTASALGS
                     SLTSHTAANQLGVTAFAPRAEPGLGTLGSLASLGGIWNGEAVPSSRTTLFAVASAVVL
                     LAMVAIGLPTVARRPVAVPLLTLAAVSVMVPAVLATGPGLHALRVVVDAAPGLGVLRD
                     GQKWVALAVPGYTLSGAGTVLTLRRWLRPATAAVVCCLALVLTLPDLAWGVWGKVAPV
                     HYPSGWAAVAAAINADPRTVAVLPAGTMRRFSWSGSAPVLDPLPRWVRADVLTTGDLV
                     ISGVTVPGEDAHARAVQELLLTGPHPSTLAAAGVGWLVVESDSAGDMGAAARTLGRLA
                     AAHRDDELALYRVGGQTSGASSARLKATMLAHWAWLSMLLVGGAGAAGYWVRRHLHHC
                     EDTPASRAQD"
     gene            complement(299604..300869)
                     /locus_tag="BCG_0264c"
                     /db_xref="GeneID:4698794"
     CDS             complement(299604..300869)
                     /locus_tag="BCG_0264c"
                     /note="Differs from Rv0227c by 1aa, R29S, and from Mb0232c
                     by 1aa, S392N"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_976362.1"
                     /db_xref="GI:121636139"
                     /db_xref="GeneID:4698794"
                     /translation="MLRFAACGAIGLGAALLIAALLLSTYTTRRIAEIPLDIDATLIS
                     DGTGTALDSASLATEHIVVNQDVPLVSQQQVTVESPANADVVTLQVGSSLRRTDKQKD
                     SGLLLAIVDTVTLNRKTAMAVSDDTHTGGAVQKPRGLNDENPPTAIPLRHDGLSYRFP
                     FHTEKKTYPYFDPIAQKAFDANYEGEEDVNGLTTYRFTQNVGYTPEGKLVAPLKYPSL
                     YAGDEDGKVTTSAAMWGLPGDPNEQITMTRYYAAQRTFWVDPVSGTIVKETERANHYF
                     ARDPLKPEVTFADYQVTSTEETVESQVNAARDERDRLALWSRVLPITFTAAGLVALVG
                     GGLFASFSLRTEGALMAASGDRDDHDYRRGGFEEPVPGAEAETEKLPTQRPDFPREPS
                     GSDPPRLGSAQPPPPPDAGHPDPGPPERR"
     misc_feature    complement(299856..300797)
                     /locus_tag="BCG_0264c"
                     /note="Protein of unknown function (DUF3068); Region:
                     DUF3068; pfam11271"
                     /db_xref="CDD:256386"
     gene            301085..302308
                     /locus_tag="BCG_0265"
                     /db_xref="GeneID:4698221"
     CDS             301085..302308
                     /locus_tag="BCG_0265"
                     /EC_number="2.3.1.-"
                     /codon_start=1
                     /transl_table=11
                     /product="integral membrane acyltransferase"
                     /protein_id="YP_976363.1"
                     /db_xref="GI:121636140"
                     /db_xref="GeneID:4698221"
                     /translation="MGPADESGAPIRPQTPHRHTVLVTNGQVVGGTRGFLPAVEGMRA
                     CAAVGVVVTHVAFQTGHSSGVGGRLFGRFDLAVAVFFAVSGFLLWRGHAAAARDLRSH
                     PRTGPYLRSRVARIMPAYVVAVVVILSLLPDADHASLTVWLANLTLTQIYVPLTLTGG
                     LTQMWSLSVEVAFYAALPVLALLGRRIPVGARVPAIAALAALSWAWGWLPLDAGSGIN
                     PLTWPPAFFSWFAAGMLLAEWAYSPVGLPHRWARRRVAMAVTALLGYLVAASPLAGPE
                     GLVPGTAAQFAVKTAMGSLVAFALVAPLVLDRPDTSHRLLGSPAMVTLGRWSYGLFIW
                     HLAALAMVFPVIGAFPFTGRMPTVLVLTLIFGFAIAAVSYALVESPCREALRRWERRN
                     EPISVGELQADAIAP"
     misc_feature    301163..302305
                     /locus_tag="BCG_0265"
                     /note="Predicted acyltransferases [Lipid metabolism];
                     Region: COG1835"
                     /db_xref="CDD:224748"
     gene            complement(302336..303016)
                     /locus_tag="BCG_0266c"
                     /db_xref="GeneID:4698790"
     CDS             complement(302336..303016)
                     /locus_tag="BCG_0266c"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_976364.1"
                     /db_xref="GI:121636141"
                     /db_xref="GeneID:4698790"
                     /translation="MRQPRRANAMGLALCIYIGSLLIYTPIHGETSRRHRRAGFKHGS
                     YRIGHDDDQRHRQRGPAASHVSASSTRRRRSRHAGRRTARGPRRSMALKYLLDTSVIK
                     RLSRPAVRRAVEPLAEAGAVARTQITDLEVGYSARNETEWQRLMVALSAFDLIESTAS
                     HHRRALGIQRLLAARSQRGRKIPDLLIAAAGEEHGLVVLHYDADFDLIAAVTGQPCQW
                     IVPAGTID"
     misc_feature    complement(302363..302734)
                     /locus_tag="BCG_0266c"
                     /note="PIN domain of the Rv0301 toxin of Mycobacterium
                     tuberculosis and other uncharacterized, annotated PilT
                     protein domain proteins; Region: PIN_MtRv0301; cd09882"
                     /db_xref="CDD:189052"
     misc_feature    complement(order(302411..302413,302465..302467,
                     302624..302626,302726..302728))
                     /locus_tag="BCG_0266c"
                     /note="putative active site [active]"
                     /db_xref="CDD:189052"
     gene            complement(303013..303993)
                     /gene="php"
                     /locus_tag="BCG_0267c"
                     /db_xref="GeneID:4695383"
     CDS             complement(303013..303993)
                     /gene="php"
                     /locus_tag="BCG_0267c"
                     /EC_number="3.1.8.1"
                     /note="Differs from Rv0230c by 1aa, E199D"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphotriesterase PHP"
                     /protein_id="YP_976365.1"
                     /db_xref="GI:121636142"
                     /db_xref="GeneID:4695383"
                     /translation="MPELNTARGPIDTADLGVTLMHEHVFIMTTEIAQNYPEAWGDED
                     KRVAGAIARLGELKARGVDTIVDLTVIGLGRYIPRIARVAAATELNIVVATGLYTYND
                     VPFYFHYLGPGAQLDGPEIMTDMFVRDIEHGIADTGIKAGILKCATDEPGLTPGVERV
                     LRAVAQAHKRTGAPISTHTHAGLRRGLDQQRIFAEEGVELSRVVIGHCGDSTDVGYLE
                     ELIAAGSYLGMDRFGVDVISPFQDRVNIVARMCERGHADKMVLSHDACCYFDALPEEL
                     VPVAMPNWHYLHIHNDVIPALKQHGVTDEQLHTMLVDNPRRIFERQGGYQ"
     misc_feature    complement(303037..303945)
                     /gene="php"
                     /locus_tag="BCG_0267c"
                     /note="Phosphotriesterase (PTE) catalyzes the hydrolysis
                     of organophosphate nerve agents, including the chemical
                     warfare agents VX, soman, and sarin as well as the
                     insecticide paraoxon. PTE exists as a homodimer with one
                     active site per monomer. The active site...; Region: PTE;
                     cd00530"
                     /db_xref="CDD:238295"
     misc_feature    complement(order(303202..303204,303373..303375,
                     303460..303462,303559..303561,303922..303924,
                     303928..303930))
                     /gene="php"
                     /locus_tag="BCG_0267c"
                     /note="active site"
                     /db_xref="CDD:238295"
     misc_feature    complement(order(303202..303204,303460..303462,
                     303700..303702,303922..303924))
                     /gene="php"
                     /locus_tag="BCG_0267c"
                     /note="substrate binding pocket [chemical binding]; other
                     site"
                     /db_xref="CDD:238295"
     misc_feature    complement(order(303589..303591,303610..303612,
                     303631..303633,303643..303645,303781..303783,
                     303907..303909))
                     /gene="php"
                     /locus_tag="BCG_0267c"
                     /note="homodimer interaction site [polypeptide binding];
                     other site"
                     /db_xref="CDD:238295"
     gene            304088..305794
                     /gene="fadE4"
                     /locus_tag="BCG_0268"
                     /db_xref="GeneID:4697037"
     CDS             304088..305794
                     /gene="fadE4"
                     /locus_tag="BCG_0268"
                     /EC_number="1.3.99.-"
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-CoA dehydrogenase fadE4"
                     /protein_id="YP_976366.1"
                     /db_xref="GI:121636143"
                     /db_xref="GeneID:4697037"
                     /translation="MLLNPNHLTRKYPDRRSGEIMAATVDFFESRGKARLKHDDHERI
                     WYSDFLDFVGRERIFASLLTPASYGADDCRWDTYRISEFAEIMGFYGLSYWYPFQVTA
                     LGLGPIWMSANEDAKRKAAAGLEAGEVFAFGLSEQTHGADVYQTDMILTPSDGGWTAN
                     GEKYYIGNANVARMVSTFGKIAGTPESQEYVFFVADSQHERYDLIKNVVNSQNYVANY
                     ALRDYPVTEADILHRGAEAFHAALNTVNVCKYNLGWGAIGMCTHALYESVTHAANRHL
                     YGTVVTDFSHVRRLLTDAYVRLIAMKLVASRASDYMRSASAADRRYLLYSPLTKAKVT
                     SEGERVITALWDVIAAKGVEKDTFFETVAREIGLLPRLEGTVHINIGLLGKFMPNYLF
                     APDSTLPVIPRRDDAADDAFLFAQGPTGGLGKVRFHDWRASFDTCAHLPNVALLREQV
                     DVFAELLASATPDAAQQKDIDFAFGVGQLFANVPYAQLILEEARLSGVDEALIDEIFG
                     VLVRDFNTHAVELHGRSATTAEQARFAMRMVRRPVHDPARYDQIWKDHVLALNGAYQM
                     AP"
     misc_feature    304139..305242
                     /gene="fadE4"
                     /locus_tag="BCG_0268"
                     /note="Acyl-CoA dehydrogenases [Lipid metabolism]; Region:
                     CaiA; COG1960"
                     /db_xref="CDD:224871"
     misc_feature    304394..305242
                     /gene="fadE4"
                     /locus_tag="BCG_0268"
                     /note="Acyl-CoA dehydrogenase; Region: ACAD; cl09933"
                     /db_xref="CDD:271680"
     misc_feature    order(304394..304396,304481..304483,304487..304489,
                     304580..304582,304586..304588,305198..305206,
                     305210..305212,305216..305218)
                     /gene="fadE4"
                     /locus_tag="BCG_0268"
                     /note="active site"
                     /db_xref="CDD:173838"
     gene            305929..306618
                     /locus_tag="BCG_0269"
                     /db_xref="GeneID:4696255"
     CDS             305929..306618
                     /locus_tag="BCG_0269"
                     /codon_start=1
                     /transl_table=11
                     /product="TetR family transcriptional regulator"
                     /protein_id="YP_976367.1"
                     /db_xref="GI:121636144"
                     /db_xref="GeneID:4696255"
                     /translation="MPTVTWARVDPARRAAVVEAAEAEFGAHGFSRGSLNVIARRAGV
                     AKGSLFQYFADKRDLYAFIADIASQRVRSYMEDLIRELDPNRPFFEFLTDLLDGWVAY
                     FAEHPRERALHAAATLEVDTDARISVRSVLHRHYLDVLRPLVRDAHARGDLRADSDTG
                     ALMSLLLLIFPHLALAPYMRGLDPILGLDEPTPEQPALAVRRLVAVLAAAFDAQHPAT
                     NSAQTRSEEIT"
     misc_feature    306001..306480
                     /locus_tag="BCG_0269"
                     /note="Transcriptional regulator [Transcription]; Region:
                     AcrR; COG1309"
                     /db_xref="CDD:224228"
     misc_feature    306001..306111
                     /locus_tag="BCG_0269"
                     /note="Bacterial regulatory proteins, tetR family; Region:
                     TetR_N; pfam00440"
                     /db_xref="CDD:249860"
     gene            306615..307559
                     /gene="nrdB"
                     /locus_tag="BCG_0270"
                     /db_xref="GeneID:4695750"
     CDS             306615..307559
                     /gene="nrdB"
                     /locus_tag="BCG_0270"
                     /EC_number="1.17.4.1"
                     /note="Catalyzes the rate-limiting step in dNTP synthesis"
                     /codon_start=1
                     /transl_table=11
                     /product="ribonucleotide-diphosphate reductase subunit
                     beta"
                     /protein_id="YP_976368.1"
                     /db_xref="GI:121636145"
                     /db_xref="GeneID:4695750"
                     /translation="MTRTRSGSLAAGGLNWASLPLKLFAGGNAKFWDPADIDFTRDRA
                     DWEKLSDDERDYATRLCTQFIAGEEAVTEDIQPFMSAMRAEGRLADEMYLTQFAFEEA
                     KHTQVFRMWLDAVGISEDLHRYLDDLPAYRQIFYAELPECLNALSADPSPAAQVRASV
                     TYNHIVEGMLALTGYYAWHKICVERAILPGMQELVRRIGDDERRHMAWGTFTCRRHVA
                     ADDANWTVFETRMNELIPLALRLIEEGFALYGDQPPFDLSKDDFLQYSTDKGMRRFGT
                     ISNARGRPVAEIDVDYSPAQLEDTFADEDRRTLAAASA"
     misc_feature    306648..307493
                     /gene="nrdB"
                     /locus_tag="BCG_0270"
                     /note="Ribonucleotide Reductase R2-like protein,
                     Mn/Fe-binding domain; Region: RNRR2_Rv0233_like; cd07911"
                     /db_xref="CDD:153120"
     misc_feature    order(306780..306782,306804..306806,306816..306818,
                     306825..306827,306903..306905,306915..306917,
                     306924..306926,307017..307019,307110..307115,
                     307125..307127,307134..307136,307143..307145,
                     307218..307220,307227..307229,307335..307337,
                     307350..307352,307398..307400)
                     /gene="nrdB"
                     /locus_tag="BCG_0270"
                     /note="active site"
                     /db_xref="CDD:153120"
     misc_feature    order(306816..306818,306915..306917,306924..306926,
                     307113..307115,307137..307139,307218..307220,
                     307227..307229)
                     /gene="nrdB"
                     /locus_tag="BCG_0270"
                     /note="diiron metal binding site [ion binding]; other
                     site"
                     /db_xref="CDD:153120"
     gene            complement(307635..309170)
                     /gene="gabD1"
                     /locus_tag="BCG_0271c"
                     /db_xref="GeneID:4698713"
     CDS             complement(307635..309170)
                     /gene="gabD1"
                     /locus_tag="BCG_0271c"
                     /EC_number="1.2.1.16"
                     /standard_name="gabD2"
                     /note="NADP-dependent semialdehyde dehydrogenase; part of
                     alternative pathway from alpha-ketoglutarate to succinate"
                     /codon_start=1
                     /transl_table=11
                     /product="succinate-semialdehyde dehydrogenase"
                     /protein_id="YP_976369.1"
                     /db_xref="GI:121636146"
                     /db_xref="GeneID:4698713"
                     /translation="MRSVTCSATLVLPVIEPTPADRRPRHLLLGSAGHVSGRLDTGRF
                     VQTHPAKDVSVPIATINPATGETVKTFTAATDDEVDAAIARAHRRFADYRQTSFAQRA
                     RWANATADLLEAEADQAAAMMTLEMGKTLAAAKAEALKCAKGFRYYAENAEALLADEP
                     ADAAKVGASAAYGRYQPLGVILAVMPWNFPLWQAVRFAAPALMAGNVGLLKHASNVPQ
                     CALYLADVIARGGFPDGCFQTLLVSSGAVEAILRDPRVAAATLTGSEPAGQSVGAIAG
                     NEIKPTVLELGGSDPFIVMPSADLDAAVSTAVTGRVQNNGQSCIAAKRFIVHADIYDD
                     FVDKFVARMAALRVGDPTDPDTDVGPLATEQGRNEVAKQVEDAAAAGAVIRCGGKRLD
                     RPGWFYPPTVITDISKDMALYTEEVFGPVASVFRAANIDEAVEIANATTFGLGSNAWT
                     RDETEQRRFIDDIVAGQVFINGMTVSYPELPFGGVKRSGYGRELSAHGIREFCNIKTV
                     WIA"
     misc_feature    complement(307641..308936)
                     /gene="gabD1"
                     /locus_tag="BCG_0271c"
                     /note="Mycobacterium tuberculosis succinate-semialdehyde
                     dehydrogenase 1-like; Region: ALDH_SSADH1_GabD1; cd07100"
                     /db_xref="CDD:143418"
     misc_feature    complement(order(307725..307727,307839..307841,
                     307917..307919,307923..307925,308214..308216,
                     308310..308318,308358..308363,308370..308372,
                     308379..308390,308529..308534,308538..308540,
                     308583..308585,308607..308621))
                     /gene="gabD1"
                     /locus_tag="BCG_0271c"
                     /note="NAD(P) binding site [chemical binding]; other site"
                     /db_xref="CDD:143418"
     misc_feature    complement(order(308214..308216,308223..308225,
                     308316..308318,308607..308609))
                     /gene="gabD1"
                     /locus_tag="BCG_0271c"
                     /note="catalytic residues [active]"
                     /db_xref="CDD:143418"
     gene            complement(309196..310644)
                     /locus_tag="BCG_0272c"
                     /db_xref="GeneID:4695548"
     CDS             complement(309196..310644)
                     /locus_tag="BCG_0272c"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_976370.1"
                     /db_xref="GI:121636147"
                     /db_xref="GeneID:4695548"
                     /translation="MGWFSAPEYWLGRLALERGTAIIYLIAFVAAAQQFRPLIGEHGM
                     LPVPRYLAGQSFWRTPSIFHFRYSDRVFAGVCWLGAVLSAAVVAGAASFVPLWATMLI
                     WLTLWVLYLSIVNVGQAWYSFGWESLLLETGFLMIFLGNERTAPPILTLLLARWLLFR
                     VEFGAGLIKMRGDSCWRSLTCLYYHHETQPMPGPLSWFFHHLPKPLHRIEVAGNHFAQ
                     LVVPFGLFTPQPAASIAAAIIVVTQLWLVASGNFSWLNWLTILLACSAIDTSSAAALL
                     PMPAQPALSAPPQWFAGLVVVFTAAVLLLSYWPARNLLSSHQRMNMSFNPFHLVNTYG
                     AFGSICRTRREVVIEGTDESPITEQTVWKAYEFKGKPGDPRRLPRQWAPYHLRLDWLM
                     WFAAISPGYALPWMTPFLNRLLRNDPATLKLLRHNPFPQSPPRYVRAQLYQYRFTTVA
                     ELRRDRAWWHRTLIGRYVPPMSLRKVASPPAD"
     misc_feature    complement(309223..310284)
                     /locus_tag="BCG_0272c"
                     /note="Lipase maturation factor; Region: LMF1; pfam06762"
                     /db_xref="CDD:253900"
     gene            complement(310679..314881)
                     /locus_tag="BCG_0273c"
                     /db_xref="GeneID:4698499"
     CDS             complement(310679..314881)
                     /locus_tag="BCG_0273c"
                     /note="Differs from Rv0236c by 3aa, V412M, A990T, G1080S"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_976371.1"
                     /db_xref="GI:121636148"
                     /db_xref="GeneID:4698499"
                     /translation="MAPLSRKWLPVVGAVALALTFAQSPGQVSPDTKLDLTANPLRFL
                     ARATNLWNSDLPFGQAQNQAYGYLFPHGTFFVIGHLLGVPGWVTQRLWWAVLLTVGFW
                     GLLRVAEALGVGGPSSRVVGAVAFALSPRVLTTLGSISSETLPMMLAPWVLLPTILAL
                     RGTSGRSVRALAAQAGLAVALMGAVNAIATLAGCLPAVIWWACHRPNRLWWRYTAWWL
                     LAMALATLWWVMALTQLHGVSPPFLDFIESSGVTTQWSSLVEVLRGTDSWTPFVAPNA
                     TAGAPLVTGSAAILGTCLVAAAGLAGLTSPAMPARGRLVTMLLVGVVLLAVGHRGGLA
                     SPVAHPVQAFLDAAGTPLRNVHKVGPVIRLPLVLGLAQLLSRVPLPGSAPRPAWLRAF
                     AHPERDKRVAVAVVALTALVVSTSLAWTGRVAPPGTFGALPQYWQEAADWLRTHHAAT
                     PTPGRVLVVPGAPFATQVWGTSHDEPLQVLGDGPWGVRDSIPLTPPQTIRALDSVQRL
                     FAAGRPSAGLADTLARQGISYVLVRNDLDPETSRSARPILLHRSIAGSPGLAKLAEFG
                     APVGPDPLAGFVNDSGLRPRYPAIEIYRVSAPANPGAPYFAATDQLARVDGGPEVLLR
                     LDERRRLQGQPPLGPVLMTADARAAGLPVPQVAVTDTPVARETDYGRVDHHSSAIRAP
                     GDARHTYNRVPDYPVPGAEPVVGGWTGGRITVSSSSADATAMPDVAPASAPAAAVDGD
                     PATAWVSNALQAAVGQWLQVDFDRPVTNAVVTLTPSATAVGAQVRRILIETVNGSTTL
                     RFDEAGKPLTAALPYGETPWVRFTAAATDDGSAGVQFGITDLAITQYDASGFAHPVQL
                     RHTVLVPGPPPGSAIAGWDLGSELLGRPGCAPGPDGVRCAASMALAPEEPANLSRTLT
                     VPRPVSVTPMVWVRPRQGPKLADLIAAPSTTRASGDSDLVDILGSAYAAADGDPATAW
                     TAPQRVVQHKTPPTLTLALPRPTVVTGLRLAASRSMLPAHPTVVAINLGDGPQVRQLQ
                     VGELTTLWLHPRVTDTVSVSLLDWDDVIDRNALGFDQLKPPGLAEVVVLGAGGAPIAP
                     ADAARNRARALTVDCDHGPVVAVAGRFVHTSIRTTVGALLDGEPVAALPCEREPIALP
                     AGQQELLISPGAAFVVDGAQLSTPGAGLSSATVTSAETGAWGPTHREVRVPESATSRV
                     LVVPESINSGWVARTSTGARLTPIAVNGWQQAWVVPAGNPGTITLTFAPNSLYRASLA
                     IGLALLPLLALLAFWRTGRRQLADRPTPPWRPGAWAAAGVLAAGAVIASIAGVMVMGT
                     ALGVRYALRRRERLRDRVTVGLAAGGLILAGAALSRHPWRSVDGYAGNWASVQLLALI
                     SVSVVAASVVATSESRGQDRMQ"
     misc_feature    complement(312800..314842)
                     /locus_tag="BCG_0273c"
                     /note="Domain of unknown function (DUF3367); Region:
                     DUF3367; pfam11847"
                     /db_xref="CDD:256668"
     gene            complement(314928..315101)
                     /locus_tag="BCG_0274c"
                     /db_xref="GeneID:4698021"
     CDS             complement(314928..315101)
                     /locus_tag="BCG_0274c"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_976372.1"
                     /db_xref="GI:121636149"
                     /db_xref="GeneID:4698021"
                     /translation="MNRIVAPAAASVVVGLLLGAAAIFGVTLMVQQDKKPPLPGGDPS
                     SSVLNRVEYGNRS"
     misc_feature    complement(314934..315101)
                     /locus_tag="BCG_0274c"
                     /note="Protein of unknown function (DUF2613); Region:
                     DUF2613; pfam11021"
                     /db_xref="CDD:151468"
     gene            315216..316382
                     /gene="lpqI"
                     /locus_tag="BCG_0275"
                     /db_xref="GeneID:4698823"
     CDS             315216..316382
                     /gene="lpqI"
                     /locus_tag="BCG_0275"
                     /note="Differs from Rv0237 by 1aa, L129V"
                     /codon_start=1
                     /transl_table=11
                     /product="lipoprotein lpqI"
                     /protein_id="YP_976373.1"
                     /db_xref="GI:121636150"
                     /db_xref="GeneID:4698823"
                     /translation="MAFPRTLAILAAAAALVVACSHGGTPTGSSTTSGASPATPVAVP
                     VPRSCAEPAGIPALLSPRDKLAQLLVVGVRDAADAQAVVTNYHVGGILIGSDTDLTIF
                     DGALAEIVAGGGPLPLAVSVDEEGGRLSRLRSLIGGTGPSARELAQTRTVQQVRDLAR
                     DRGRQMRKLGITIDFAPVVDVTDAPDDTVIGDRSFGSDPATVTAYAGAYAQGLRDAGV
                     LPVLKHFPGHGRGSGDSHNGGVTTPPLDDLVGDDLVPYRTLVTQAPVGVMVGHLQVPG
                     LTGSEPASLSKAAVNLLRTGTGYGAPPFDGPVFSDDLSGMAAISDRFGVSEAVLRTLQ
                     AGADIALWVTTKEVPAVLDRLEQALRAGELPMSAVDRSVVRVATMKGPNPGCGR"
     misc_feature    315390..>316355
                     /gene="lpqI"
                     /locus_tag="BCG_0275"
                     /note="Beta-glucosidase-related glycosidases [Carbohydrate
                     transport and metabolism]; Region: BglX; COG1472"
                     /db_xref="CDD:224389"
     gene            316458..317072
                     /locus_tag="BCG_0276"
                     /db_xref="GeneID:4698156"
     CDS             316458..317072
                     /locus_tag="BCG_0276"
                     /codon_start=1
                     /transl_table=11
                     /product="TetR family transcriptional regulator"
                     /protein_id="YP_976374.1"
                     /db_xref="GI:121636151"
                     /db_xref="GeneID:4698156"
                     /translation="MAGGTKRLPRAVREQQMLDAAVQMFSVNGYHETSMDAIAAEAQI
                     SKPMLYLYYGSKEDLFGACLNREMSRFIDALRSSINFDQSPKDLLRNTIVSFLRYIDA
                     NRASWIVMYTQATSSQAFAHTVREGREQIVQLVAELVRAGTRGPLTDAEIEMMAVALV
                     GAGEAVATRLGIGDTDVDEAAEMMINLFWLGLKGAPVDRLETGH"
     misc_feature    316458..317042
                     /locus_tag="BCG_0276"
                     /note="Transcriptional regulator [Transcription]; Region:
                     AcrR; COG1309"
                     /db_xref="CDD:224228"
     misc_feature    316509..316646
                     /locus_tag="BCG_0276"
                     /note="Bacterial regulatory proteins, tetR family; Region:
                     TetR_N; pfam00440"
                     /db_xref="CDD:249860"
     gene            317134..317367
                     /locus_tag="BCG_0277"
                     /db_xref="GeneID:4696734"
     CDS             317134..317367
                     /locus_tag="BCG_0277"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_976375.1"
                     /db_xref="GI:121636152"
                     /db_xref="GeneID:4696734"
                     /translation="MIRTQVQLPDELYRDAKRVAHEHEMTLAEVVRRGLEHMVRIYPR
                     RDAASDTWQPPTPRRLGPFRASEETWRELANEA"
     gene            317375..317812
                     /locus_tag="BCG_0278"
                     /db_xref="GeneID:4698779"
     CDS             317375..317812
                     /locus_tag="BCG_0278"
                     /note="Differs from Rv0240 by 1aa, S31A"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_976376.1"
                     /db_xref="GI:121636153"
                     /db_xref="GeneID:4698779"
                     /translation="MLSIDTNILLYAQNRDCPEHDAAAAFLVECSGRADVAVCELVLM
                     ELYQLLRNPTVVTRPLEGPEAAEVCQTFRRNRRWALLENAPVMNEVWVLAATPRIARR
                     RLFDARLALTLRHHGVDEFATRNINGFTDFGFSRVWDPITSDG"
     misc_feature    317375..317803
                     /locus_tag="BCG_0278"
                     /note="Mycobacterium tuberculosis PIN domain family;
                     Region: Mtu_PIN_fam; TIGR00028"
                     /db_xref="CDD:232790"
     gene            complement(317842..318684)
                     /locus_tag="BCG_0279c"
                     /db_xref="GeneID:4698015"
     CDS             complement(317842..318684)
                     /locus_tag="BCG_0279c"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_976377.1"
                     /db_xref="GI:121636154"
                     /db_xref="GeneID:4698015"
                     /translation="MTQPSGLKNLLRAAAGALPVVPRTDQLPNRTVTVEELPIDPANV
                     AAYAAVTGLRYGNQVPLTYPFALTFPSVMSLVTGFDFPFAAMGAIHTENHITQYRPIA
                     VTDAVGVRVRAENLREHRRGLLVDLVTNVSVGNDVAWHQVTTFLHQQRTSLSGEPKPP
                     PQKKPKLPPPAAVLRITPAKIRRYAAVGGDHNPIHTNPIAAKLFGFPTVIAHGMFTAA
                     AVLANIEARFPDAVRYSVRFAKPVLLPATAGLYVAEGDGGWDLTLRNMAKGYPHLTAT
                     VRGL"
     misc_feature    complement(318298..>318567)
                     /locus_tag="BCG_0279c"
                     /note="The hotdog fold was initially identified in the E.
                     coli FabA (beta-hydroxydecanoyl-acyl carrier protein
                     (ACP)-dehydratase) structure and subsequently in 4HBT
                     (4-hydroxybenzoyl-CoA thioesterase) from Pseudomonas. A
                     number of other seemingly unrelated...; Region: hot_dog;
                     cl00509"
                     /db_xref="CDD:271497"
     misc_feature    complement(317857..318165)
                     /locus_tag="BCG_0279c"
                     /note="MaoC like domain; Region: MaoC_dehydratas;
                     pfam01575"
                     /db_xref="CDD:250715"
     misc_feature    complement(order(317962..317973,318046..318051))
                     /locus_tag="BCG_0279c"
                     /note="active site 2 [active]"
                     /db_xref="CDD:239524"
     misc_feature    complement(order(317986..317994,318016..318018,
                     318031..318033))
                     /locus_tag="BCG_0279c"
                     /note="active site 1 [active]"
                     /db_xref="CDD:239524"
     gene            complement(318695..320059)
                     /gene="fabG"
                     /locus_tag="BCG_0280c"
                     /db_xref="GeneID:4695780"
     CDS             complement(318695..320059)
                     /gene="fabG"
                     /locus_tag="BCG_0280c"
                     /EC_number="1.1.1.100"
                     /note="Catalyzes the first of the two reduction steps in
                     the elongation cycle of fatty acid synthesis"
                     /codon_start=1
                     /transl_table=11
                     /product="3-ketoacyl-ACP reductase"
                     /protein_id="YP_976378.1"
                     /db_xref="GI:121636155"
                     /db_xref="GeneID:4695780"
                     /translation="MAPKRSSDLFSQVVNSGPGSFLARQLGVPQPETLRRYRAGEPPL
                     TGSLLIGGAGRVVEPLRAALEKDYDLVGNNLGGRWADSFGGLVFDATGITEPAGLKGL
                     HEFFTPVLRNLGRCGRVVVVGGTPEAAASTNERIAQRALEGFTRSLGKELRRGATTAL
                     VYLSPDAKPAATGLESTMRFLLSAKSAYVDGQVFSVGADDSTPPADWEKPLDGKVAIV
                     TGAARGIGATIAEVFARDGAHVVAIDVESAAENLAETASKVGGTALWLDVTADDAVDK
                     ISEHLRDHHGGKADILVNNAGITRDKLLANMDDARWDAVLAVNLLAPLRLTEGLVGNG
                     SIGEGGRVIGLSSIAGIAGNRGQTNYATTKAGMIGITQALAPGLAAKGITINAVAPGF
                     IETQMTAAIPLATREVGRRLNSLLQGGQPVDVAEAIAYFASPASNAVTGNVIRVCGQA
                     MIGA"
     misc_feature    complement(318698..320041)
                     /gene="fabG"
                     /locus_tag="BCG_0280c"
                     /note="3-ketoacyl-(acyl-carrier-protein) reductase;
                     Provisional; Region: fabG; PRK08261"
                     /db_xref="CDD:236207"
     misc_feature    complement(318716..319420)
                     /gene="fabG"
                     /locus_tag="BCG_0280c"
                     /note="Short-chain dehydrogenases/reductases (SDR);
                     Region: SDR; cl21454"
                     /db_xref="CDD:271874"
     misc_feature    complement(order(318881..318892,318968..318970,
                     318980..318982,319019..319027,319169..319177,
                     319322..319330,319385..319387,319391..319396,
                     319400..319402))
                     /gene="fabG"
                     /locus_tag="BCG_0280c"
                     /note="NAD(P) binding site [chemical binding]; other site"
                     /db_xref="CDD:187535"
     misc_feature    complement(order(318968..318970,318980..318982,
                     319019..319021,319103..319105))
                     /gene="fabG"
                     /locus_tag="BCG_0280c"
                     /note="active site"
                     /db_xref="CDD:187535"
     gene            320201..321523
                     /gene="fadA2"
                     /locus_tag="BCG_0281"
                     /db_xref="GeneID:4697071"
     CDS             320201..321523
                     /gene="fadA2"
                     /locus_tag="BCG_0281"
                     /EC_number="2.3.1.9"
                     /note="Catalyzes the synthesis of acetoacetyl coenzyme A
                     from two molecules of acetyl coenzyme A. It can also act
                     as a thiolase, catalyzing the reverse reaction and
                     generating two-carbon units from the four-carbon product
                     of fatty acid oxidation"
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA acetyltransferase"
                     /protein_id="YP_976379.1"
                     /db_xref="GI:121636156"
                     /db_xref="GeneID:4697071"
                     /translation="MAPAAKNTSQTRRRVAVLGGNRIPFARSDGAYADASNQDMFTAA
                     LSGLVDRFGLAGERLDMVVGGAVLKHSRDFNLMRECVLGSELSPYTPAFDLQQACGTG
                     LQAAIAAADGIAAGRYEVAAAGGVDTTSDPPIGLGDDLRRTLLKLRRSRSNVQRLKLV
                     GTLPASLGVEIPANSEPRTGLSMGEHAAVTAKQMGIKRVDQDELAAASHRNMADAYDR
                     GFFDDLVSPFLGLYRDDNLRPNSSVEKLATLRPVFGVKAGDATMTAGNSTPLTDGASV
                     ALLASEQWAEAHSLAPLAYLVDAETAAVDYVNGNDGLLMAPTYAVPRLLARNGLSLQD
                     FDFYEIHEAFASVVLAHLAAWESEEYCKRRLGLDAALGSIDRSKLNVNGSSLAAGHPF
                     AATGGRILAQTAKQLAEKKAAKKGGGPLRGLISICAAGGQGVAAILEA"
     misc_feature    320219..321520
                     /gene="fadA2"
                     /locus_tag="BCG_0281"
                     /note="acetyl-CoA acetyltransferase; Provisional; Region:
                     PRK09268"
                     /db_xref="CDD:236440"
     misc_feature    320246..321520
                     /gene="fadA2"
                     /locus_tag="BCG_0281"
                     /note="Thiolase are ubiquitous enzymes that catalyze the
                     reversible thiolytic cleavage of 3-ketoacyl-CoA into
                     acyl-CoA and acetyl-CoA, a 2-step reaction involving a
                     covalent intermediate formed with a catalytic cysteine.
                     They are found in prokaryotes and...; Region: thiolase;
                     cd00751"
                     /db_xref="CDD:238383"
     misc_feature    order(320300..320302,320381..320383,320423..320425,
                     320432..320434,320444..320446,320477..320488,
                     320510..320512,320531..320536,320543..320545,
                     320588..320590,321095..321097,321101..321103,
                     321107..321109,321179..321181,321488..321493)
                     /gene="fadA2"
                     /locus_tag="BCG_0281"
                     /note="dimer interface [polypeptide binding]; other site"
                     /db_xref="CDD:238383"
     misc_feature    order(320495..320497,321368..321370,321479..321481)
                     /gene="fadA2"
                     /locus_tag="BCG_0281"
                     /note="active site"
                     /db_xref="CDD:238383"
     gene            complement(321829..323664)
                     /gene="fadE5"
                     /locus_tag="BCG_0282c"
                     /db_xref="GeneID:4698442"
     CDS             complement(321829..323664)
                     /gene="fadE5"
                     /locus_tag="BCG_0282c"
                     /EC_number="1.3.99.-"
                     /note="Differs from Mb0250c by 1aa, N503D and from Rv0244c
                     by 3aa, R394K, A479E, N503D"
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-CoA dehydrogenase fadE5"
                     /protein_id="YP_976380.1"
                     /db_xref="GI:121636157"
                     /db_xref="GeneID:4698442"
                     /translation="MSHYRSNVRDQVFNLFEVLGVDKALGHGEFSDVDVDTARDMLAE
                     VSRLAEGPVAESFVEGDRNPPVFDPKTHSVMLPESFKKSVNAMLEAGWDKVGIDEALG
                     GMPMPKAVVWALHEHILGANPAVWMYAGGAGFAQILYHLGTEEQKKWAVLAAERGWGS
                     TMVLTEPDAGSDVGAARTKAVQQADGSWHIDGVKRFITSGDSGDLFENIFHLVLARPE
                     GAGPGTKGLSLYFVPKFLFDVETGEPGERNGVFVTNVEHKMGLKVSATCELAFGQHGV
                     PAKGWLVGEVHNGIAQMFEVIEQARMMVGTKAIATLSTGYLNALQYAKSRVQGADLTQ
                     MTDKTAPRVTITHHPDVRRSLMTQKAYAEGLRALYLYTATFQDAAVAEVVHGVDAKLA
                     VRVNDLMLPVVKGVGSEQAYAKLTESLQTLGGSGFLQDYPIEQYIRDAKIDSLYEGTT
                     AIQAQDFFFRKIVRDKGVALAHVSGQIQAFVDSGAGNGRLKTERALLAKALTNVQGMA
                     AALTGYLMAAQQDVTSLYKVGLGSVRFLMSVGDLIIGWLLQRQAAVAVAALDAGATGD
                     ERSFYEGKVAVASFFAKNFLPLLTSTREVIETLDNDIMELDEAAF"
     misc_feature    complement(323563..323661)
                     /gene="fadE5"
                     /locus_tag="BCG_0282c"
                     /note="Acyl-CoA dehydrogenase N terminal; Region:
                     AcylCoA_DH_N; pfam12418"
                     /db_xref="CDD:257037"
     misc_feature    complement(321832..323658)
                     /gene="fadE5"
                     /locus_tag="BCG_0282c"
                     /note="acyl-CoA dehydrogenase; Provisional; Region:
                     PTZ00456"
                     /db_xref="CDD:185635"
     misc_feature    complement(322276..323544)
                     /gene="fadE5"
                     /locus_tag="BCG_0282c"
                     /note="Putative acyl-CoA dehydrogenases similar to fadE5;
                     Region: ACAD_fadE5; cd01153"
                     /db_xref="CDD:173842"
     misc_feature    complement(order(322312..322314,322318..322320,
                     322339..322341,323071..323073,323077..323079,
                     323152..323157,323170..323175,323179..323181))
                     /gene="fadE5"
                     /locus_tag="BCG_0282c"
                     /note="FAD binding site [chemical binding]; other site"
                     /db_xref="CDD:173842"
     misc_feature    complement(order(322321..322326,322990..322992,
                     323152..323154))
                     /gene="fadE5"
                     /locus_tag="BCG_0282c"
                     /note="substrate binding site [chemical binding]; other
                     site"
                     /db_xref="CDD:173842"
     misc_feature    complement(322321..322326)
                     /gene="fadE5"
                     /locus_tag="BCG_0282c"
                     /note="catalytic residues [active]"
                     /db_xref="CDD:173842"
     misc_feature    complement(321841..322251)
                     /gene="fadE5"
                     /locus_tag="BCG_0282c"
                     /note="Acetyl-CoA dehydrogenase C-terminal like; Region:
                     Acyl-CoA_dh_C; pfam12806"
                     /db_xref="CDD:257313"
     gene            324036..324524
                     /locus_tag="BCG_0283"
                     /db_xref="GeneID:4696256"
     CDS             324036..324524
                     /locus_tag="BCG_0283"
                     /EC_number="1.-.-.-"
                     /codon_start=1
                     /transl_table=11
                     /product="oxidoreductase"
                     /protein_id="YP_976381.1"
                     /db_xref="GI:121636158"
                     /db_xref="GeneID:4696256"
                     /translation="MNSTNNLTPSSLREAFGHFPTGVVAIAAEVDGVRQGLAASTFVP
                     VSLEPPLVSFCVQNTSTTWPKLTGVPMLGISVLGEAHDAAVRTLAAKTGDRFAGLETV
                     SNDAGAVFIKGTSVWLESAIEQLVPAGDHTIVVLRVNQVKVDPNVAPIVFHRSVLRRL
                     GV"
     misc_feature    324066..324521
                     /locus_tag="BCG_0283"
                     /note="Conserved protein/domain typically associated with
                     flavoprotein oxygenases, DIM6/NTAB family [General
                     function prediction only]; Region: COG1853"
                     /db_xref="CDD:224766"
     gene            324840..326150
                     /locus_tag="BCG_0284"
                     /db_xref="GeneID:4698092"
     CDS             324840..326150
                     /locus_tag="BCG_0284"
                     /note="Differs from Rv0246 by 1aa, A129V"
                     /codon_start=1
                     /transl_table=11
                     /product="integral membrane protein"
                     /protein_id="YP_976382.1"
                     /db_xref="GI:121636159"
                     /db_xref="GeneID:4698092"
                     /translation="MAKTSHRVSSADGMSKRILRLIIAQSGFYSAALQLGNVSIVLPF
                     VVAELDAELWIAALIFPAFTAGGAIGNVVAPPAVAAVPRRHRLFIIVSCLAVLAGVNA
                     LCATIGKGSVAGILLVVNVTLIGVVSAISFVAFADLVAAMPSGTARARILLTEVGVGA
                     ALTAVVAATLSFVPDQHPLSRNIHLLWTAAVAMAISAAICRALPHRIVPRVHAAPGLH
                     KLVYVGWTAIRTNGWYRRYLLVQVLFGSVVLGSSFHSIRVAAVPGDQPDEVVAVVLFV
                     CVGLLGGIALWNRVRERFGLVGLFVGSALVSIAAAVLSIAFDLAGAWPNVVAIGLVIA
                     LVSIANQSVFTAGQLWIARDAEPGLRTSLISFGQLVINAGLVGMGLALGLIAQDHDAV
                     WPVMIVLLLNLTAAYSATRFAPAKSVDVRGLPQVSRTSRPKTGG"
     gene            complement(326147..326893)
                     /locus_tag="BCG_0285c"
                     /db_xref="GeneID:4698720"
     CDS             complement(326147..326893)
                     /locus_tag="BCG_0285c"
                     /EC_number="1.3.99.1"
                     /note="catalyzes the fumarate and succinate
                     interconversion; fumarate reductase is used under
                     anaerobic conditions with glucose or glycerol as carbon
                     source"
                     /codon_start=1
                     /transl_table=11
                     /product="fumarate reductase iron-sulfur subunit"
                     /protein_id="YP_976383.1"
                     /db_xref="GI:121636160"
                     /db_xref="GeneID:4698720"
                     /translation="MTYSASMRVWRGDESCGELREFTVEVNEGEVVLDVILRLQQTQT
                     PDLAVRWNCKAGKCGSCSAEINGKPRLMCMTRMSTFDEDEIVTVTPMRTFPVIRDLVT
                     DVSFNYQKAREIPSFAPPKELQPSEYRMAQVDVARSQEFRKCIECFLCQNVCHVVRDH
                     EENKDAFAGPRFLMRIAELEMHPLDTRDRRSQAQEEHGLGYCNITKCCTEVCPENIKI
                     TDNALIPMKERVADRKYDPVVWLGSKLFRR"
     misc_feature    complement(326150..326893)
                     /locus_tag="BCG_0285c"
                     /note="fumarate reductase iron-sulfur subunit;
                     Provisional; Region: PRK12386"
                     /db_xref="CDD:237086"
     misc_feature    complement(326657..326848)
                     /locus_tag="BCG_0285c"
                     /note="2Fe-2S iron-sulfur cluster binding domain.
                     Iron-sulfur proteins play an important role in electron
                     transfer processes and in various enzymatic reactions. The
                     family includes plant and algal ferredoxins, which act as
                     electron carriers in photosynthesis...; Region: fer2;
                     cd00207"
                     /db_xref="CDD:238126"
     misc_feature    complement(order(326675..326680,326711..326722,
                     326726..326728,326735..326737,326744..326749))
                     /locus_tag="BCG_0285c"
                     /note="catalytic loop [active]"
                     /db_xref="CDD:238126"
     misc_feature    complement(order(326675..326677,326711..326713,
                     326720..326722,326735..326737))
                     /locus_tag="BCG_0285c"
                     /note="iron binding site [ion binding]; other site"
                     /db_xref="CDD:238126"
     misc_feature    complement(326246..326476)
                     /locus_tag="BCG_0285c"
                     /note="4Fe-4S dicluster domain; Region: Fer4_8; pfam13183"
                     /db_xref="CDD:257551"
     gene            complement(326894..328834)
                     /gene="sdhA"
                     /locus_tag="BCG_0286c"
                     /db_xref="GeneID:4695826"
     CDS             complement(326894..328834)
                     /gene="sdhA"
                     /locus_tag="BCG_0286c"
                     /EC_number="1.3.5.1"
                     /note="part of four member succinate dehydrogenase enzyme
                     complex that forms a trimeric complex (trimer of
                     tetramers); SdhA/B are the catalytic subcomplex and can
                     exhibit succinate dehydrogenase activity in the absence of
                     SdhC/D which are the membrane components and form
                     cytochrome b556; SdhC binds ubiquinone; oxidizes succinate
                     to fumarate while reducing ubiquinone to ubiquinol"
                     /codon_start=1
                     /transl_table=11
                     /product="succinate dehydrogenase flavoprotein subunit"
                     /protein_id="YP_976384.1"
                     /db_xref="GI:121636161"
                     /db_xref="GeneID:4695826"
                     /translation="MVEVERHSYDVVVIGAGGAGLRAVIEARERGLKVAVVCKSLFGK
                     AHTVMAEGGCAAAMGNANPKDNWKTHFGDTMRGGKFLNNWRMAELHAKEAPDRVWELE
                     TYGALFDRTDDGRISQRNFGGHTYPRLAHVGDRTGLELIRTLQQKVVSLQQEDHAELG
                     DYEARIKVFAECTITELLKDQGAIAGAFGYWRESGRFIVFEAPAVVLATGGIGKSFKV
                     TSNSWEYTGDGHALALRAGATLINMEFVQFHPTGMVWPPSVKGILVTEGVRGDGGVLK
                     NSENSRFMFDYIPPVFKGQYAETEEEADQWLKDNDSARRTPDLLPRDEVARAINSEVK
                     AGRGTPHGGVYLDIASRLTPAEIKRRLPSMYHQFKELAEVDITTQAMEVGPTCHYVMG
                     GVEVDADTGAATVPGLFAAGECAGGMHGSNRLGGNSLSDLLVFGRRAGLGAADYVRAL
                     SSRPAVSAEAIDAAAQQALSPFEGPKDGSAPENPYALHMDLQYVMNDLVGIIRNADEI
                     SRALTLLAELWSRYHNVLVEGHRQYNPGWNLSIDLRNMLLVSECVARAALQRTESRGG
                     HTRDDHPGMDPNWRRILLVCRATETMGTGGSGSGDSNCHINVTQQLQTPMRPDLLELF
                     EISELEKYYTDEELAEHPGRRG"
     misc_feature    complement(326915..328834)
                     /gene="sdhA"
                     /locus_tag="BCG_0286c"
                     /note="succinate dehydrogenase flavoprotein subunit;
                     Reviewed; Region: sdhA; PRK07803"
                     /db_xref="CDD:236101"
     misc_feature    complement(327512..328810)
                     /gene="sdhA"
                     /locus_tag="BCG_0286c"
                     /note="Short-chain dehydrogenases/reductases (SDR);
                     Region: SDR; cl21454"
                     /db_xref="CDD:271874"
     misc_feature    complement(<327092..327373)
                     /gene="sdhA"
                     /locus_tag="BCG_0286c"
                     /note="Fumarate reductase flavoprotein C-term; Region:
                     Succ_DH_flav_C; pfam02910"
                     /db_xref="CDD:251613"
     gene            complement(328865..329686)
                     /locus_tag="BCG_0287c"
                     /db_xref="GeneID:4696782"
     CDS             complement(328865..329686)
                     /locus_tag="BCG_0287c"
                     /codon_start=1
                     /transl_table=11
                     /product="succinate dehydrogenase membrane anchor subunit"
                     /protein_id="YP_976385.1"
                     /db_xref="GI:121636162"
                     /db_xref="GeneID:4696782"
                     /translation="MSAPTANRPAIGVFTPTRAQIPERTLRTDLWWLPPLLTNLGLLA
                     FICYATTRAFWGSQYWVEKYHYLTPFYSPCVSASCQPGASHLGVWFGHFPGWIPLGAM
                     VLPFLLGFRLTCYYYRKAYYRSVWQSPTSCAVPEPRAHYTGETRLPLIVQNTHRYFFY
                     IAVVVSLINTYDAIAAFHSPSGFGFGLGNVILTINVVLLWAYTISCHSCRHATGGRLK
                     HFSKHPVRYWIWTQVSKLNTRHMQFAWITLGTLALTDFYIMLVASGSITDLRFIG"
     gene            complement(329766..330059)
                     /locus_tag="BCG_0288c"
                     /db_xref="GeneID:4697759"
     CDS             complement(329766..330059)
                     /locus_tag="BCG_0288c"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_976386.1"
                     /db_xref="GI:121636163"
                     /db_xref="GeneID:4697759"
                     /translation="MSTTAELAELHDLVGGLRRCVTALKARFGDNPATRRIVIDADRI
                     LTDIELLDTDVSELDLERAAVPQPSEKIAIPDTEYDREFWRDVDDEGVGGHRY"
     gene            complement(330204..330683)
                     /gene="hsp"
                     /locus_tag="BCG_0289c"
                     /db_xref="GeneID:4695359"
     CDS             complement(330204..330683)
                     /gene="hsp"
                     /locus_tag="BCG_0289c"
                     /standard_name="hsp 20; hrpA; acr2"
                     /codon_start=1
                     /transl_table=11
                     /product="heat shock protein hsp"
                     /protein_id="YP_976387.1"
                     /db_xref="GI:121636164"
                     /db_xref="GeneID:4695359"
                     /translation="MNNLALWSRPVWDVEPWDRWLRDFFGPAATTDWYRPVAGDFTPA
                     AEIVKDGDDAVVRLELPGIDVDKDVNVELDPGQPVSRLVIRGEHRDEHTQDAGDKDGR
                     TLREIRYGSFRRSFRLPAHVTSEAIAASYDAGVLTVRVAGAYKAPAETQAQRIAITK"
     misc_feature    complement(330213..330632)
                     /gene="hsp"
                     /locus_tag="BCG_0289c"
                     /note="Molecular chaperone (small heat shock protein)
                     [Posttranslational modification, protein turnover,
                     chaperones]; Region: IbpA; COG0071"
                     /db_xref="CDD:223149"
     misc_feature    complement(330264..330542)
                     /gene="hsp"
                     /locus_tag="BCG_0289c"
                     /note="Alpha-crystallin domain (ACD) of
                     alpha-crystallin-type small(s) heat shock proteins (Hsps).
                     sHsps are small stress induced proteins with monomeric
                     masses between 12 -43 kDa, whose common feature is the
                     Alpha-crystallin domain  (ACD). sHsps are generally...;
                     Region: ACD_sHsps-like; cd06464"
                     /db_xref="CDD:107221"
     misc_feature    complement(order(330279..330284,330342..330344,
                     330498..330503,330507..330509,330513..330515,
                     330531..330542))
                     /gene="hsp"
                     /locus_tag="BCG_0289c"
                     /note="putative dimer interface [polypeptide binding];
                     other site"
                     /db_xref="CDD:107221"
     gene            330897..333458
                     /gene="nirB"
                     /locus_tag="BCG_0290"
                     /db_xref="GeneID:4697339"
     CDS             330897..333458
                     /gene="nirB"
                     /locus_tag="BCG_0290"
                     /EC_number="1.7.1.4"
                     /codon_start=1
                     /transl_table=11
                     /product="nitrite reductase NAD(P)H] large subunit"
                     /protein_id="YP_976388.1"
                     /db_xref="GI:121636165"
                     /db_xref="GeneID:4697339"
                     /translation="MPTAGSSRAPAAAREIVVVGHGMVGHRLVEAVRARDADGSLRIT
                     VLAEEGDAAYDRVGLTSYTESWDRALLALPGNDYAGDQRVRLLLNTRVTQIDRATKSV
                     VTAAGQRHRYDTLVLATGSYAFVPPVPGHDLPACHVYRTFDDLDAIRAGAQRTLDGGH
                     TDGGVVIGGGLLGLEAANALRQFGLQTHVVEMMPRLMAQQIDEAGGALLARMIADLGI
                     AVHVGTGTESIESVKHSDGSVWARVRLSDGEVIDAGVVIFAAGIRPRDELARAAGLAI
                     GDRGGVLTDLSCRTSDPDIYAVGEVAAIDGRCYGLVGPGYTSAEVVADRLLDGSAEFP
                     EADLSTKLKLLGVDVASFGDAMGATENCLEVVINDAVKRTYAKLVLSDDATTLLGGVL
                     VGDASSYGVLRPMVGAELPGDPLALIAPAGSGAGAGALGVGALPDSAQICSCNNVTKG
                     ELKCAIADGCGDVPALKSCTAAGTSCGSCVPLLKQLLEAEGVEQSKALCEHFSQSRAE
                     LFEIITATEVRTFSGLLDRFGRGKGCDICKPVVASILASTGSDHILDGEQASLQDSND
                     HFLANIQKNGSYSVVPRVPGGDIKPEHLILIGQIAQDFGLYTKITGGQRIDLFGARVD
                     QLPLIWQRLVDGGMESGHAYGKAVRTVKSCVGSDWCRYGQQDSVQLAIDLELRYRGLR
                     APHKIKLGVSGCARECAEARGKDVGVIATEKGWNLYVAGNGGMTPKHAQLLASDLDKE
                     TLIRYIDRFLIYYIRTADRLQRTAPWVESLGLDHVREVVCEDSLGLAEEFEAAMQRHV
                     ANYKCEWKGVLEDPDKLSRFVSFVNAPDAVDSTVTFTERAGRKVPVSIGIPRVRS"
     misc_feature    330942..333332
                     /gene="nirB"
                     /locus_tag="BCG_0290"
                     /note="nitrite reductase [NAD(P)H], large subunit; Region:
                     nitri_red_nirB; TIGR02374"
                     /db_xref="CDD:162827"
     misc_feature    331407..331640
                     /gene="nirB"
                     /locus_tag="BCG_0290"
                     /note="Pyridine nucleotide-disulphide oxidoreductase;
                     Region: Pyr_redox; pfam00070"
                     /db_xref="CDD:249559"
     misc_feature    332211..332366
                     /gene="nirB"
                     /locus_tag="BCG_0290"
                     /note="BFD-like [2Fe-2S] binding domain; Region: Fer2_BFD;
                     pfam04324"
                     /db_xref="CDD:252526"
     misc_feature    332613..332792
                     /gene="nirB"
                     /locus_tag="BCG_0290"
                     /note="Nitrite/Sulfite reductase ferredoxin-like half
                     domain; Region: NIR_SIR_ferr; pfam03460"
                     /db_xref="CDD:251971"
     misc_feature    332826..333242
                     /gene="nirB"
                     /locus_tag="BCG_0290"
                     /note="Nitrite and sulphite reductase 4Fe-4S domain;
                     Region: NIR_SIR; pfam01077"
                     /db_xref="CDD:250346"
     gene            333484..333840
                     /gene="nirD"
                     /locus_tag="BCG_0291"
                     /db_xref="GeneID:4699206"
     CDS             333484..333840
                     /gene="nirD"
                     /locus_tag="BCG_0291"
                     /EC_number="1.7.1.4"
                     /codon_start=1
                     /transl_table=11
                     /product="nitrite reductase [NAD(P)H] small subunit nirD"
                     /protein_id="YP_976389.1"
                     /db_xref="GI:121636166"
                     /db_xref="GeneID:4699206"
                     /translation="MTLLNDIQVWTTACAYDHLIPGRGVGVLLDDGSQVALFRLDDGS
                     VHAVGNVDPFSGAAVMSRGIVGDRGGRAMVQSPILKQAFALDDGSCLDDPRVSVPVYP
                     ARVTPEGRIQVARVAV"
     misc_feature    333511..333825
                     /gene="nirD"
                     /locus_tag="BCG_0291"
                     /note="Assimilatory nitrite reductase (NirD) family,
                     Rieske domain; Assimilatory nitrate and nitrite reductases
                     convert nitrate through nitrite to ammonium. Members
                     include bacterial and fungal proteins. The bacterial NirD
                     contains a single Rieske domain while...; Region:
                     Rieske_NirD; cd03529"
                     /db_xref="CDD:239605"
     gene            complement(333856..334380)
                     /gene="cobU"
                     /locus_tag="BCG_0292c"
                     /db_xref="GeneID:4699207"
     CDS             complement(333856..334380)
                     /gene="cobU"
                     /locus_tag="BCG_0292c"
                     /EC_number="2.-.-.-"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional cobalamin biosynthesis protein
                     cobU: cobinamide kinase + cobinamide phosphate
                     guanylyltransferase"
                     /protein_id="YP_976390.1"
                     /db_xref="GI:121636167"
                     /db_xref="GeneID:4699207"
                     /translation="MRILVTGGVRSGKSTHAEALLGDAADVVYVAPGRPAAGSDPDWD
                     ARVALHRARRPPTWLTVETADVATALSEARSPVLVDCLGTWLTAIMDGEALWSAATAD
                     VYAVLEARLDGLCAALTGLPTAIVVTNEVGLGVVPSHSSGVLFRDLLGTINRRVAAVC
                     DEVHLVIAGRVLKL"
     misc_feature    complement(333859..334380)
                     /gene="cobU"
                     /locus_tag="BCG_0292c"
                     /note="Adenosyl cobinamide kinase/adenosyl cobinamide
                     phosphate guanylyltransferase [Coenzyme metabolism];
                     Region: CobU; COG2087"
                     /db_xref="CDD:224998"
     misc_feature    complement(order(334339..334347,334357..334362))
                     /gene="cobU"
                     /locus_tag="BCG_0292c"
                     /note="Walker A motif; other site"
                     /db_xref="CDD:238540"
     misc_feature    complement(order(334138..334143,334285..334290,
                     334294..334296,334339..334347,334357..334359))
                     /gene="cobU"
                     /locus_tag="BCG_0292c"
                     /note="ATP binding site [chemical binding]; other site"
                     /db_xref="CDD:238540"
     misc_feature    complement(334141..334155)
                     /gene="cobU"
                     /locus_tag="BCG_0292c"
                     /note="Walker B motif; other site"
                     /db_xref="CDD:238540"
     gene            complement(334405..335889)
                     /gene="cobQ1"
                     /locus_tag="BCG_0293c"
                     /db_xref="GeneID:4697940"
     CDS             complement(334405..335889)
                     /gene="cobQ1"
                     /locus_tag="BCG_0293c"
                     /note="catalyzes amidations at positions B, D, E, and G on
                     adenosylcobyrinic A,C-diamide. NH(2) groups are provided
                     by glutamine, and one molecule of ATP is hydrogenolyzed
                     for each amidation"
                     /codon_start=1
                     /transl_table=11
                     /product="cobyric acid synthase"
                     /protein_id="YP_976391.1"
                     /db_xref="GI:121636168"
                     /db_xref="GeneID:4697940"
                     /translation="MSGLLVAGTTSDAGKSAVTAGLCRALARRGVRVAPFKAQNMSNN
                     SMVCRGPDGTGVEIGRAQWVQALAARTTPEAAMNPVLLKPASDHRSHVVLMGKPWGEV
                     ASSSWCAGRRALAEAACRAFDALAARYDVVVAEGAGSPAEINLRAGDYVNMGLARHAG
                     LPTIVVGDIDRGGVFAAFLGTVALLAAEDQALVAGFVVNKFRGDSDLLAPGLRDLERV
                     TGRRVYGTLPWHPDLWLDSEDALDLQGRRAAGTGARRVAVVRLPRISNFTDVDALGLE
                     PDLDVVFASDPRALDDADLIVLPGTRATIADLAWLRARDLDRALLVHVAAGKPLLGIC
                     GGFQMLGRVIRDPYGIEGPGGQVTEVEGLGLLDVETAFSPHKVLRLPRGEGLGVPASG
                     YEIHHGRITRGDTAEEFLGGARDGPVFGTMWHGSLEGDALREAFLRETLGLAPSGSCF
                     LAARERRLDLLGDLVERHLDVDALLNLARHGCPPTLPFLAPGAP"
     misc_feature    complement(334456..335889)
                     /gene="cobQ1"
                     /locus_tag="BCG_0293c"
                     /note="cobyric acid synthase; Provisional; Region:
                     PRK00784"
                     /db_xref="CDD:234838"
     misc_feature    complement(335194..335889)
                     /gene="cobQ1"
                     /locus_tag="BCG_0293c"
                     /note="ATP-binding cassette transporter nucleotide-binding
                     domain; Region: ABC_ATPase; cl21455"
                     /db_xref="CDD:271875"
     misc_feature    complement(334579..335124)
                     /gene="cobQ1"
                     /locus_tag="BCG_0293c"
                     /note="Type 1 glutamine amidotransferase (GATase1) domain
                     found in Cobyric Acid Synthase (CobQ); Region:
                     GATase1_CobQ; cd01750"
                     /db_xref="CDD:153221"
     misc_feature    complement(order(334696..334698,334702..334704,
                     334888..334890))
                     /gene="cobQ1"
                     /locus_tag="BCG_0293c"
                     /note="catalytic triad [active]"
                     /db_xref="CDD:153221"
     gene            complement(335908..337578)
                     /gene="PPE2"
                     /locus_tag="BCG_0294c"
                     /db_xref="GeneID:4698555"
     CDS             complement(335908..337578)
                     /gene="PPE2"
                     /locus_tag="BCG_0294c"
                     /codon_start=1
                     /transl_table=11
                     /product="PPE family protein"
                     /protein_id="YP_976392.1"
                     /db_xref="GI:121636169"
                     /db_xref="GeneID:4698555"
                     /translation="MTAPIWMASPPEVHSALLSSGPGPGPLLVSAEGWHSLSIAYAET
                     ADELAALLAAVQAGTWDGPTAAVYVAAHTPYLAWLVQASANSAAMATRQETAATAYGT
                     ALAAMPTLAELGANHALHGVLMATNFFGINTIPIALNESDYARMWIQAATTMASYQAV
                     STAAVAAAPQTTPAPQIVKANAPTAASDEPNQVQEWLQWLQKIGYTDFYNNVIQPFIN
                     WLTNLPFLQAMFSGFDPWLPSLGNPLTFLSPANIAFALGYPMDIGSYVAFLSQTFAFI
                     GADLAAAFASGNPATIAFTLMFTTVEAIGTIITDTIALVKTLLEQTLALLPAALPLLA
                     APLAPLTLAPASAAGGFAGLSGLAGLVGIPPSAPPVIPPVAAIAPSIPTPTPTPAPAP
                     APTAVTAPTPPPGPPPPPVTAPPPVTGAGIQSFGYLVGDLNSAAQARKAVGTGVRKKT
                     PEPDSAEAPAAAAAPEEQVQPQRRRRPKIKQLGRGYEYLDLDPETGHDPTGSPQGAGT
                     LGFAGTTHKASPGQVAGLITLPNDAFGGSPRTPMMPGTWDTDSATRVE"
     misc_feature    complement(335926..337569)
                     /gene="PPE2"
                     /locus_tag="BCG_0294c"
                     /note="PPE-repeat proteins [Cell motility and secretion];
                     Region: COG5651"
                     /db_xref="CDD:227938"
     misc_feature    complement(337105..337557)
                     /gene="PPE2"
                     /locus_tag="BCG_0294c"
                     /note="PPE family; Region: PPE; pfam00823"
                     /db_xref="CDD:250158"
     gene            337886..338104
                     /locus_tag="BCG_0295"
                     /db_xref="GeneID:4697069"
     CDS             337886..338104
                     /locus_tag="BCG_0295"
                     /note="In Mycobacterium bovis BCG Pasteur, and
                     Mycobacterium bovis, a single base transition (c-t) leads
                     to a truncated product in the 5' direction compared to
                     Mycobacterium tuberculosis strain H37Rv (72 aa versus 124
                     aa)"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_976393.1"
                     /db_xref="GI:121636170"
                     /db_xref="GeneID:4697069"
                     /translation="MQSVDLHVERHLPSRGRSHRTVATVTCVTALGDIRSAQLSATGA
                     WPAVLFPSWSWLCGIGGGVDLQKPSCRA"
     gene            complement(338325..338780)
                     /locus_tag="BCG_0296c"
                     /db_xref="GeneID:4695376"
     CDS             complement(338325..338780)
                     /locus_tag="BCG_0296c"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_976394.1"
                     /db_xref="GI:121636171"
                     /db_xref="GeneID:4695376"
                     /translation="MARSQEPSRGLLDPVAKMLRLPFGTPDFIEKIVTGSVNQVGRRT
                     LYVLITTWDAAGGGPFAASAIATTGLAKTAEIVQSMFIGPVFNPLLKMLGADKIAIRA
                     SLCAAQLVGLGIMRYGVRSEPLHSMSVEMLVDAIGPTMQRYLVGDIGRG"
     gene            complement(338805..339548)
                     /locus_tag="BCG_0297c"
                     /db_xref="GeneID:4698229"
     CDS             complement(338805..339548)
                     /locus_tag="BCG_0297c"
                     /note="Differs from Rv0259c by 1aa, V182A"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_976395.1"
                     /db_xref="GI:121636172"
                     /db_xref="GeneID:4698229"
                     /translation="MNLILTAHGTRRPSGVAMIADIAAQVSALVDRTVQVAFVDVLGP
                     SPSEVLSALSCRPAIVVPAFLSRGYHVRTDLPAHVAASAHPHVTVTPALGPCREIAQI
                     VTQQLVESGWRPGDSVILAAAGASDRRARADLHTTRTLVSELTGSWVDMGFAGTGGPD
                     VRTAVQRARDRAEANRGARRVVVASFLLAEGLFQERLRASGADVVTRPLGTHPGLAQL
                     VANRFRSAVARQQRLHRWHGTPTPVTLDL"
     misc_feature    complement(338853..339548)
                     /locus_tag="BCG_0297c"
                     /note="Sirohydrochlorin ferrochelatase [Inorganic ion
                     transport and metabolism]; Region: COG2138"
                     /db_xref="CDD:225049"
     misc_feature    complement(339267..339542)
                     /locus_tag="BCG_0297c"
                     /note="Sirohydrochlorin cobalt chelatase (CbiX) and
                     sirohydrochlorin iron chelatase (SirB), N-terminal domain.
                     SirB catalyzes the ferro-chelation of sirohydrochlorin to
                     siroheme, the prosthetic group of sulfite and nitrite
                     reductases. CbiX is a cobaltochelatase; Region:
                     CbiX_SirB_N; cd03416"
                     /db_xref="CDD:239509"
     misc_feature    complement(order(339339..339341,339525..339527))
                     /locus_tag="BCG_0297c"
                     /note="putative active site [active]"
                     /db_xref="CDD:239509"
     misc_feature    complement(338868..339203)
                     /locus_tag="BCG_0297c"
                     /note="Sirohydrochlorin cobalt chelatase (CbiX) and
                     sirohydrochlorin iron chelatase (SirB), C-terminal domain.
                     SirB catalyzes the ferro-chelation of sirohydrochlorin to
                     siroheme, the prosthetic group of sulfite and nitrite
                     reductases. CbiX is a cobaltochelatase; Region:
                     CbiX_SirB_C; cd03414"
                     /db_xref="CDD:239507"
     misc_feature    complement(order(338973..338975,339180..339182))
                     /locus_tag="BCG_0297c"
                     /note="putative active site [active]"
                     /db_xref="CDD:239507"
     gene            complement(339545..340690)
                     /locus_tag="BCG_0298c"
                     /db_xref="GeneID:4699345"
     CDS             complement(339545..340690)
                     /locus_tag="BCG_0298c"
                     /EC_number="4.2.1.75"
                     /note="catalyzes the formation of uroporphyrinogen-III
                     from hydroxymethylbilane"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional uroporphyrinogen-III
                     synthetase/response regulator domain-containing protein"
                     /protein_id="YP_976396.1"
                     /db_xref="GI:121636173"
                     /db_xref="GeneID:4699345"
                     /translation="MAQAHSAPLTGYRIAVTSARRAEELCALLRRQGAEVCSAPAIKM
                     IALPDDDELQNNTEALIADPPDILVAHTGIGFRGWLAAAEGWGLANELLESLSSARII
                     SRGPKATGALRAAGLREEWSPDSESSHEVLEYLLESGVSRTRIAVQLHGAADSWDPFP
                     EFLGGLRFAGAQVVPIRVYRWKPAPLGGVFDHLVTGIARRQFDAVTFTSAPAAAAVLE
                     RSRELDIEDQLLAALRTDVHAMCVGPVTSRPLIRKGVPTSAPERMRLGALARHIAEEL
                     PLLGSCTFKAAGHVIEIRGTSVLVDDSVKPLSPSGMAILRALVHRPGGVVSRGDLLRV
                     LPGDGSDTHAVDTAVLRLRTALGDKNIVATVVKRGYRLAVDSRHDDV"
     misc_feature    complement(339548..340690)
                     /locus_tag="BCG_0298c"
                     /note="bifunctional uroporphyrinogen-III
                     synthetase/response regulator domain protein; Validated;
                     Region: PRK07239"
                     /db_xref="CDD:235981"
     misc_feature    complement(339875..340651)
                     /locus_tag="BCG_0298c"
                     /note="Uroporphyrinogen-III synthase (HemD) catalyzes the
                     asymmetrical cyclization of tetrapyrrole (linear) to
                     uroporphyrinogen-III, the fourth step in the biosynthesis
                     of heme. This ubiquitous enzyme is present in eukaryotes,
                     bacteria and archaea. Mutations in...; Region: HemD;
                     cd06578"
                     /db_xref="CDD:119440"
     misc_feature    complement(order(340055..340069,340148..340150,
                     340154..340156,340241..340243,340370..340372,
                     340469..340477))
                     /locus_tag="BCG_0298c"
                     /note="active site"
                     /db_xref="CDD:119440"
     misc_feature    complement(<339548..339865)
                     /locus_tag="BCG_0298c"
                     /note="DNA-binding winged-HTH domains [Transcription];
                     Region: CadC; COG3710"
                     /db_xref="CDD:226233"
     misc_feature    complement(order(339584..339586,339599..339601,
                     339623..339628,339650..339652,339659..339661,
                     339707..339712,339767..339769))
                     /locus_tag="BCG_0298c"
                     /note="DNA binding site [nucleotide binding]"
                     /db_xref="CDD:238225"
     gene            complement(340790..342199)
                     /gene="narK3"
                     /locus_tag="BCG_0299c"
                     /db_xref="GeneID:4698915"
     CDS             complement(340790..342199)
                     /gene="narK3"
                     /locus_tag="BCG_0299c"
                     /codon_start=1
                     /transl_table=11
                     /product="integral membrane nitrite extrusion protein
                     narK3"
                     /protein_id="YP_976397.1"
                     /db_xref="GI:121636174"
                     /db_xref="GeneID:4698915"
                     /translation="MGRSHQISDWDPEDSVAWEAGNKFIARRNLIWSVAAEHVGFSVW
                     SLWSVMVLFMPTSVYGFSAGDKFLLGATATLVGACLRFPYTFATAKFGGRNWTIFSAL
                     VLLIPTVGSILLLANPGLPLWPYLVCGALAGLGGGNFAASMTNINAFFPQRLKGAALA
                     LNAGGGNLGVPMVQLVGLLVIATAGDREPYWVCAIYLVLLAVAGLGAALYMDNLTEYR
                     IELNTMRAVVSEPHTWVISLLYIGTFGSFIGFSFAFGQVLQINFIASGQSTAQASLHA
                     AQIAFLGPLLGSLSRIYGGKLADRIGGGRVTLAAFCAMLLATGILISASTFGDHLAGP
                     MPTATMVGYVIGFTALFILSGIGNGSVYKMIPSIFEARSHSLQISEAERRQWSRSMSG
                     ALIGLAGAVGALGGVGVNLALRESYLTSGTATSAFWAFGVFYLVASVLTWAIYVRRGL
                     KSAGELVPATTAPAGLAYV"
     misc_feature    complement(340856..342187)
                     /gene="narK3"
                     /locus_tag="BCG_0299c"
                     /note="The Major Facilitator Superfamily (MFS) is a large
                     and diverse group of secondary transporters that includes
                     uniporters, symporters, and antiporters. MFS proteins
                     facilitate the transport across cytoplasmic or internal
                     membranes of a variety of...; Region: MFS; cl21472"
                     /db_xref="CDD:271892"
     misc_feature    complement(340820..342157)
                     /gene="narK3"
                     /locus_tag="BCG_0299c"
                     /note="Nitrate/nitrite transporter [Inorganic ion
                     transport and metabolism]; Region: NarK; COG2223"
                     /db_xref="CDD:225133"
     gene            complement(342340..342885)
                     /gene="aac"
                     /locus_tag="BCG_0300c"
                     /db_xref="GeneID:4697467"
     CDS             complement(342340..342885)
                     /gene="aac"
                     /locus_tag="BCG_0300c"
                     /EC_number="2.3.1.-"
                     /standard_name="aac(2')-IC"
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside 2'-n-acetyltransferase aac"
                     /protein_id="YP_976398.1"
                     /db_xref="GI:121636175"
                     /db_xref="GeneID:4697467"
                     /translation="MHTQVHTARLVHTADLDSETRQDIRQMVTGAFAGDFTETDWEHT
                     LGGMHALIWHHGAIIAHAAVIQRRLIYRGNALRCGYVEGVAVRADWRGQRLVSALLDA
                     VEQVMRGAYQLGALSSSARARRLYASRGWLPWHGPTSVLAPTGPVRTPDDDGTVFVLP
                     IDISLDTSAELMCDWRAGDVW"
     misc_feature    complement(342562..342735)
                     /gene="aac"
                     /locus_tag="BCG_0300c"
                     /note="N-Acyltransferase superfamily: Various enzymes that
                     characteristically catalyze the transfer of an acyl group
                     to a substrate; Region: NAT_SF; cd04301"
                     /db_xref="CDD:173926"
     misc_feature    complement(order(342595..342600,342628..342636))
                     /gene="aac"
                     /locus_tag="BCG_0300c"
                     /note="Coenzyme A binding pocket [chemical binding]; other
                     site"
                     /db_xref="CDD:173926"
     gene            complement(342895..343797)
                     /locus_tag="BCG_0301c"
                     /db_xref="GeneID:4698700"
     CDS             complement(342895..343797)
                     /locus_tag="BCG_0301c"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_976399.1"
                     /db_xref="GI:121636176"
                     /db_xref="GeneID:4698700"
                     /translation="MTTLEILRSGPLALVEDLGRAGLAHLGVGRSGAADRRSHTLANR
                     LVANPDDWATVEVTFGGFSARVRGGDVDIAVTGADTDPTVNGIMVGTNSIHHVRDGQV
                     ISLGTPRAGLRTYLAVRGGVCVEPVLGSRSYDVMSAIGPSPLRAGDVLPVGEHTDDYP
                     ELDQAPVAAIEEHLVELRVVPGPRDDWLVDPDALVHTIWMASNRSDRVGMRLQGRPLQ
                     HRWPDRQLPGEGVTRGAIQVPPNGLPVILGPDHPITGSYPVVGVITDEDIDKVAQIRP
                     GQYVRLHWARPRSRLPGQGVTQAW"
     misc_feature    complement(342898..343791)
                     /locus_tag="BCG_0301c"
                     /note="Allophanate hydrolase subunit 2; Region: AHS2;
                     cl00865"
                     /db_xref="CDD:260667"
     gene            complement(343814..344446)
                     /locus_tag="BCG_0302c"
                     /db_xref="GeneID:4699153"
     CDS             complement(343814..344446)
                     /locus_tag="BCG_0302c"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_976400.1"
                     /db_xref="GI:121636177"
                     /db_xref="GeneID:4699153"
                     /translation="MDAALACTVLDYGDHALMLQCDSTADAMAWTDALRAAALPGVVD
                     IVAASRTVLVKLDAPRYQGVTRQRLRRLRVTPEAVAAADHRCDLVIDVVYDGPDLAEV
                     ARCTGLTTAAVINAHTATGWRAGFSGSAPGFAYLIDGDPSLRVPRRPERRTSMPPGSV
                     ALADGFSAIYPSQAPSDWQIIGHTDAVLWDVDRPQPALLTPGMWVQFRAA"
     misc_feature    complement(343817..344434)
                     /locus_tag="BCG_0302c"
                     /note="Allophanate hydrolase subunit 1 [Amino acid
                     transport and metabolism]; Region: DUR1; COG2049"
                     /db_xref="CDD:224960"
     gene            complement(344542..345534)
                     /locus_tag="BCG_0303c"
                     /db_xref="GeneID:4697220"
     CDS             complement(344542..345534)
                     /locus_tag="BCG_0303c"
                     /note="Differs from Rv0265c and Mb0271c by 1aa, C313Y"
                     /codon_start=1
                     /transl_table=11
                     /product="periplasmic iron-transport lipoprotein"
                     /protein_id="YP_976401.1"
                     /db_xref="GI:121636178"
                     /db_xref="GeneID:4697220"
                     /translation="MRQGCSRRGFLQVAEAAAATGLFAGCSSPKPPPGTPGGAAVTIT
                     HLFGQTVIKEPPKRVVSAGYTEQDDLLAVDVVPIAVTDWFGDQPFAVWPWAAPKLGGA
                     RPAVLNLDNGIQIDRIAALKPDLIVAINAGVDADTYQQLSAIAPTVAQSGGDAFFEPW
                     KDQARSIGQAVFAADRMRSLIEAVDQKFAAVAQRHPRWRGKKALLLQGRLWQGNVVAT
                     LAGWRTDFLNDMGLVIADSIKPFAVDQRGVIPRDHIKAVLDAADVLIWMTESPEDEKA
                     LLADPEIAASQATAQRRHIFTSKEQAGAIAFSSVLSCPVVAEQLPPQISQILGA"
     misc_feature    complement(344545..345489)
                     /locus_tag="BCG_0303c"
                     /note="ABC-type Fe3+-hydroxamate transport system,
                     periplasmic component [Inorganic ion transport and
                     metabolism]; Region: FepB; COG0614"
                     /db_xref="CDD:223687"
     misc_feature    complement(344692..345375)
                     /locus_tag="BCG_0303c"
                     /note="Helical backbone metal receptor (TroA-like domain).
                     These proteins have been shown to function in the ABC
                     transport of ferric siderophores and metal ions such as
                     Mn2+, Fe3+, Cu2+ and/or Zn2+.  Their ligand binding site
                     is formed in the interface between...; Region: TroA-like;
                     cl00262"
                     /db_xref="CDD:260309"
     misc_feature    complement(order(345028..345030,345106..345108,
                     345115..345120))
                     /locus_tag="BCG_0303c"
                     /note="intersubunit interface [polypeptide binding]; other
                     site"
                     /db_xref="CDD:238347"
     gene            complement(345556..349185)
                     /gene="oplA"
                     /locus_tag="BCG_0304c"
                     /db_xref="GeneID:4695900"
     CDS             complement(345556..349185)
                     /gene="oplA"
                     /locus_tag="BCG_0304c"
                     /EC_number="3.5.2.9"
                     /codon_start=1
                     /transl_table=11
                     /product="5-oxoprolinase"
                     /protein_id="YP_976402.1"
                     /db_xref="GI:121636179"
                     /db_xref="GeneID:4695900"
                     /translation="MVGAGWHFWVDRGGTFTDVVARRPDGRLLTHKLLSDNPARYRDA
                     AVAGIRALLANGEAGTRVDAVRMGTTVATNALLERTGERTLLVITRGFGDALRIAYQN
                     RPRIFDRRIVLPEMLYERVVEVDERVTADGRVLRAPDLEALGEKMRQAHADGIRAVAV
                     VCLHSYLYPGHEREIGTLAQRIGFAQISLSSEVSPLMKLVPRGDTTVVDAYLSPVLRR
                     YINQVADQMRGVRLMFMQSNGGLAQAGHFRGKDAILSGPAGGIVGMVRMSALAGFDHV
                     IGFDMGGTSTDVSHYAGEYERVFTTQVAGVRLRAPMLDIHTVAAGGGSILHFDGSRYR
                     VGPDSAGADPGPACYRGGGPLCVTDANVMLGRIQPTHFPSVFGPSGDQPLDAGTVRRG
                     FTDLAADIAARTGDDRSPEQVAEGYLRIAVANMANAVKKISVQKGHDVTRYALTTFGG
                     AGGQHACAVADALGIRTVLIPPMAGVLSALGIGLADTTAMREQSVEIPLGPAAPQRLA
                     SVAESLERAARAELLDEGVPGERIRVVRRVHLRYEGTDTAIPVQLAEIETMATAFESS
                     HRALYTFLLDRPLIAEAISVEATGLTDQPDLSQLGDQANDTTGSSETVRIYSNGLWRD
                     APLRRREAMRPGDVLTGPAIIAEANATTVVDDGWQATMTETGHLLAQRVVTPPRPDAA
                     TRAGFEAGFEADPVLLEIFNNLFMSIAEQMGFRLEATAQSVNIRERLDFSCALFDPDG
                     NLVANAPHIPVHLGSMGTTVKEVIRRRLSGMKPGDVYAVNDPYHGGTHLPDITVITPV
                     FNTGGEDVLFFVASRGHHAEIGGITPGSMPADSREIHEEGVLFDNWLLAENGRFREAE
                     TRRLLTEAPFGSRNPDTNLADLRAQIAANQKGVDEVGKMIDHFGRDVVAAYMRHVQDN
                     AEEAVRRVIDRLDNGAYRYRMDSGATIAVRITVDRAARSATIDFTGTSAQLDTNFNAP
                     TSVVNAAVLYVFRTLVADDIPLNDGCLRPLRIVVPEGSMLAPTHPAAVVAGNVETSQA
                     ITGALFAALGVQAEGSGTMNNVTFGNERHQYYETVGSGSGAGDGYHGASVVQTHMTNS
                     RLTDPEVLEWRYPVLLREFAVRQGSGGAGRWRGGDGAVRRLEFTEPMTVSTLSGHRRV
                     RPYGMAGGSPGELGRNRVERADGSTVELAGCGSTHVEPGDTLVIETPGGGGYGPASTS
                     ARRRR"
     misc_feature    complement(345580..349167)
                     /gene="oplA"
                     /locus_tag="BCG_0304c"
                     /note="5-oxoprolinase; Region: PLN02666"
                     /db_xref="CDD:215358"
     misc_feature    complement(348637..349167)
                     /gene="oplA"
                     /locus_tag="BCG_0304c"
                     /note="Hydantoinase/oxoprolinase N-terminal region;
                     Region: Hydant_A_N; pfam05378"
                     /db_xref="CDD:253171"
     misc_feature    complement(347719..348582)
                     /gene="oplA"
                     /locus_tag="BCG_0304c"
                     /note="Hydantoinase/oxoprolinase; Region: Hydantoinase_A;
                     pfam01968"
                     /db_xref="CDD:251002"
     misc_feature    complement(345559..347109)
                     /gene="oplA"
                     /locus_tag="BCG_0304c"
                     /note="Hydantoinase B/oxoprolinase; Region:
                     Hydantoinase_B; pfam02538"
                     /db_xref="CDD:251360"
     gene            349362..350753
                     /gene="narU"
                     /locus_tag="BCG_0305"
                     /db_xref="GeneID:4698680"
     CDS             349362..350753
                     /gene="narU"
                     /locus_tag="BCG_0305"
                     /codon_start=1
                     /transl_table=11
                     /product="integral membrane nitrite extrusion protein
                     narU"
                     /protein_id="YP_976403.1"
                     /db_xref="GI:121636180"
                     /db_xref="GeneID:4698680"
                     /translation="MALTTAPAIDYALPRQQDEGDHWIDDWRPEDPVFWETIGRPIAR
                     RNLIFSIFAEHVGFSVWMLWSIVVVQMTAAAPGHPAASGWALSASQALCLVAVPSGVG
                     AFLRLPYTFAIPIFGGRNWTTVSAALLVIPCLLLAWAVSHPSLPFAVLVVIAATAGFG
                     GGNFASSMANISFFYPEKDKGWALGLNAAGGNIGVAVVQKIIPPIVVAGSGVALSRAG
                     LFFVPLAVAAAVCAFLFMNNLTEAKADVKPVWQSLRHADTWIMSLLYIGTFGSFIGYS
                     AAFPTLLKTVFGRGDIALGWAFLGAGIGSLVRPLGGKLADRIGGARITAASFVMLAAG
                     AAAALWSVQSVNLPVFFVSFMFLFVATGIGNGSSYRMISRIFQVKGEVAGGDPETMVN
                     MRRQAAGALGIISSIGAFGGFVVPLAYAWSKVHFGNIEPALHFYVAFFLALLVVTWYC
                     YLRRTTPMGQVGV"
     misc_feature    349455..350732
                     /gene="narU"
                     /locus_tag="BCG_0305"
                     /note="Nitrate/nitrite transporter [Inorganic ion
                     transport and metabolism]; Region: NarK; COG2223"
                     /db_xref="CDD:225133"
     misc_feature    349611..350714
                     /gene="narU"
                     /locus_tag="BCG_0305"
                     /note="The Major Facilitator Superfamily (MFS) is a large
                     and diverse group of secondary transporters that includes
                     uniporters, symporters, and antiporters. MFS proteins
                     facilitate the transport across cytoplasmic or internal
                     membranes of a variety of...; Region: MFS; cd06174"
                     /db_xref="CDD:119392"
     misc_feature    order(349644..349646,349653..349658,349665..349667,
                     349677..349682,349686..349691,349839..349844,
                     349851..349856,349863..349868,349875..349877,
                     349911..349916,349923..349928,349944..349946,
                     350166..350168,350175..350180,350187..350192,
                     350199..350201,350241..350243,350253..350255,
                     350265..350267,350274..350276,350283..350285,
                     350427..350429,350436..350441,350448..350450,
                     350460..350465,350472..350474,350559..350564,
                     350571..350576,350583..350588,350595..350597)
                     /gene="narU"
                     /locus_tag="BCG_0305"
                     /note="putative substrate translocation pore; other site"
                     /db_xref="CDD:119392"
     gene            complement(350795..351304)
                     /locus_tag="BCG_0306c"
                     /db_xref="GeneID:4697469"
     CDS             complement(350795..351304)
                     /locus_tag="BCG_0306c"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_976404.1"
                     /db_xref="GI:121636181"
                     /db_xref="GeneID:4697469"
                     /translation="MGTRSKSRTRQLKQSNGCTATTSGASDRRRRARRRTAPAWLRED
                     EWLRHHLPHPPRQLSRCLHRRRRSACHHRYSRRTPKGGLPMTSSLVPISEARAHLSRL
                     VRESADDDVVLMNHGRPAAILISAERYESLMEELEDLRDRLSVHEREHVTMPLDKLGA
                     ELGVDIGRV"
     misc_feature    complement(350798..351058)
                     /locus_tag="BCG_0306c"
                     /note="Antitoxin of toxin-antitoxin stability system [Cell
                     division and chromosome partitioning]; Region: StbD;
                     COG2161"
                     /db_xref="CDD:225072"
     gene            complement(351369..352562)
                     /locus_tag="BCG_0307c"
                     /db_xref="GeneID:4698669"
     CDS             complement(351369..352562)
                     /locus_tag="BCG_0307c"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_976405.1"
                     /db_xref="GI:121636182"
                     /db_xref="GeneID:4698669"
                     /translation="MSRMAAPVSLDVHGRQVIVTHPGRVVFPAHNDRKGYTKFDLVRY
                     YLAVAEGAMRGVAGRPMILKRFVKGISAEAVFQKRAPANRPDWVDVAELHYASGRSAA
                     EAVIHDAAGLAWVINLGCVDLNPHPVLAGDLDHPDELRVDLDPMPGVAWQRVVEVALV
                     VREVLEDYGLTAWPKTSGSRGFHVYARIAPCWSFPQVRLAAQTVAREVERRLPDAATS
                     RWWKEEREGVFVDFNQNAKDRTVASAYSVRATPDARVSTPLHWEEVPGCDPAVFTMAT
                     VPSRLADIGDPWAGMDDAVGRLDRLLMLAEELGPPQKAQSAKPLIEIARAKTRAEAMA
                     ALDIWRDRYPGAAALLRPADVLVDGMRGPSSIWYRIRINLQHVPADQRPPQEELIADY
                     SPWPR"
     misc_feature    complement(351771..352451)
                     /locus_tag="BCG_0307c"
                     /note="LigD_Pol_like_2: Polymerase (Pol) domain of
                     bacterial LigD proteins similar to Pseudomonas aeruginosa
                     (Pae) LigD, subgroup 2. The LigD Pol domain belongs to the
                     archaeal/eukaryal primase (AEP) superfamily. In
                     prokaryotes, LigD along with Ku is required...; Region:
                     LigD_Pol_like_2; cd04865"
                     /db_xref="CDD:240135"
     misc_feature    complement(order(351813..351821,351843..351845,
                     351861..351863,351870..351872,352014..352016,
                     352020..352028,352032..352034,352131..352133,
                     352137..352139,352191..352193,352329..352331,
                     352335..352337))
                     /locus_tag="BCG_0307c"
                     /note="nucleotide binding site [chemical binding]; other
                     site"
                     /db_xref="CDD:240135"
     gene            352598..354280
                     /gene="fadD2"
                     /locus_tag="BCG_0308"
                     /db_xref="GeneID:4698035"
     CDS             352598..354280
                     /gene="fadD2"
                     /locus_tag="BCG_0308"
                     /EC_number="2.3.1.86"
                     /note="activates fatty acids by binding to coenzyme A"
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-CoA synthetase"
                     /protein_id="YP_976406.1"
                     /db_xref="GI:121636183"
                     /db_xref="GeneID:4698035"
                     /translation="MPNLTDLPGQAVSKLQKSIGQYVARGTAELHYLRKIIESGAIGL
                     EPPLNYAALAADIRKWGEVGMLPSHNARRAPNRAAVIDEEGTLTFSELDEAAHAVANG
                     LLAKGVRAGEGVAILARNHRWFVIANYGAARVGARIILLNSEFSGPQIKEVSDREGAK
                     VIIYDDEYTKAVSLAQPPLGKLRALGVNPDDDKPSGSSDETLAELIAHSSTAPAPKAS
                     RRASIIILTSGTTGTPKGANRNTPPTLAPIGGILSHVPFKAGEVTLLPSPMFHALGYM
                     HAALAMFLGSTLVLRRRFKPALVLEDIEKHKATSMVVVPVMLSRILDQLEKTEPKPDL
                     SSLKIVFVSGSQLGAELATRALGDLGPVIYNMYGSTEVAFATIAGPKDLQFNPSTVGP
                     VVKGVTVKILDENGNEVPQGAVGRIFVGNAFPFEGYTGGGGKQIIDGLLSSGDVGYFD
                     ERGLLYVSGRDDEMIVSGGENVFPAEVEDLISGHPDVVEAAAIGVDDKEFGARLRAFV
                     VKKPGADLDEDTIKQYVRDHLARYKVPREVIFLDELPRNPTGKVLKRELRKL"
     misc_feature    352637..354277
                     /gene="fadD2"
                     /locus_tag="BCG_0308"
                     /note="acyl-CoA synthetase; Validated; Region: PRK07788"
                     /db_xref="CDD:236097"
     misc_feature    352802..>353716
                     /gene="fadD2"
                     /locus_tag="BCG_0308"
                     /note="Adenylate forming domain, Class I; Region:
                     AFD_class_I; cl17068"
                     /db_xref="CDD:266508"
     misc_feature    353264..354271
                     /gene="fadD2"
                     /locus_tag="BCG_0308"
                     /note="Adenylate forming domain, Class I; Region:
                     AFD_class_I; cl17068"
                     /db_xref="CDD:266508"
     misc_feature    order(353267..353269,353276..353293,353297..353302)
                     /gene="fadD2"
                     /locus_tag="BCG_0308"
                     /note="acyl-activating enzyme (AAE) consensus motif; other
                     site"
                     /db_xref="CDD:213270"
     misc_feature    order(353267..353269,353276..353293,353297..353302)
                     /gene="fadD2"
                     /locus_tag="BCG_0308"
                     /note="acyl-activating enzyme (AAE) consensus motif; other
                     site"
                     /db_xref="CDD:213270"
     misc_feature    order(353276..353278,353624..353629,353690..353707,
                     353930..353932,353966..353968,353975..353977,
                     354008..354010,354248..354250)
                     /gene="fadD2"
                     /locus_tag="BCG_0308"
                     /note="AMP binding site [chemical binding]; other site"
                     /db_xref="CDD:213270"
     misc_feature    order(353276..353278,353396..353401,353537..353539,
                     353543..353548,353555..353557,353624..353629,
                     353690..353707,353930..353932,353966..353968,
                     353975..353977,353999..354010,354191..354193)
                     /gene="fadD2"
                     /locus_tag="BCG_0308"
                     /note="active site"
                     /db_xref="CDD:213270"
     misc_feature    order(353276..353278,353399..353401,353537..353539,
                     353543..353548,353555..353557,353624..353629,
                     353690..353707)
                     /gene="fadD2"
                     /locus_tag="BCG_0308"
                     /note="active site"
                     /db_xref="CDD:213270"
     misc_feature    order(353276..353278,353624..353629,353690..353707)
                     /gene="fadD2"
                     /locus_tag="BCG_0308"
                     /note="AMP binding site [chemical binding]; other site"
                     /db_xref="CDD:213270"
     misc_feature    order(353396..353398,353543..353548,353555..353557,
                     353624..353626,353999..354007,354173..354175,
                     354191..354193)
                     /gene="fadD2"
                     /locus_tag="BCG_0308"
                     /note="CoA binding site [chemical binding]; other site"
                     /db_xref="CDD:213270"
     gene            complement(354297..356492)
                     /gene="fadE6"
                     /locus_tag="BCG_0309c"
                     /db_xref="GeneID:4695420"
     CDS             complement(354297..356492)
                     /gene="fadE6"
                     /locus_tag="BCG_0309c"
                     /EC_number="1.3.99.-"
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-CoA dehydrogenase fadE6"
                     /protein_id="YP_976407.1"
                     /db_xref="GI:121636184"
                     /db_xref="GeneID:4695420"
                     /translation="MSIAITPEHYELADSVRSLVARVAPSEVLHAALESPVENPPPYW
                     QAAAEQGLQGVHLAESVGGQGFGILELAVVLAEFGYGAVPGPFVPSAIASALIAAHDP
                     QAKVLAELATGAAIAAYALDSGLTATRHGDVLVIRGEVRAVPAAAQASVLVLPVAIES
                     RDEWVVLRNDQLEIEAVKSLDPLRPIAHVRANAVDVSDDALLSNLTMTTAHALMSTLL
                     SAEAVGVARWATDTASAYAKIREQFGRPIGQFQAIKHKCAEMIADTERATAAVWDAAR
                     ALDDAGESSSDVEFAAAVAATLAPATAQRCTQDCIQVHGGIGFTWEHDTNVYYRRALM
                     LAACFGRGSEYPQRVVDTATTAGMRPVDIDLDPSTEKLRAQIRAEVAALKAMPREPRT
                     VAIAEGGWVLPYLPKPWGRAASPVEQIIIAQEFTAGRVKRPQIAIATWIVPSIVAFGT
                     DNQKQRLLPPTFRGDIFWCQLFSEPGAGSDLASLATKATRVDGGWRITGQKIWTTGAQ
                     YSQWGALLARTDPSAPKHNGITYFLLDMKSEGVQVKPLRELTGKEFFNTVYLDDVFVP
                     DELVLGEVNRGWEVSRNTLTAERVSIGGSDSTFLPTLGEFVDFVRDYRFEGQFDQVAR
                     HRAGQLIAEGHATKLLNLRSTLLTLAGGDPMAPAAISKLLSMRTGQGYAEFAVSSFGT
                     DAVIGDTERLPGKWGEYLLASRATTIYGGTSEVQLNIIAERLLGLPRDP"
     misc_feature    complement(355473..356492)
                     /gene="fadE6"
                     /locus_tag="BCG_0309c"
                     /note="Acyl-CoA dehydrogenases [Lipid metabolism]; Region:
                     CaiA; COG1960"
                     /db_xref="CDD:224871"
     misc_feature    complement(355488..356474)
                     /gene="fadE6"
                     /locus_tag="BCG_0309c"
                     /note="Acyl-CoA dehydrogenase; Region: ACAD; cl09933"
                     /db_xref="CDD:271680"
     misc_feature    complement(order(356061..356063,356067..356069,
                     356130..356132,356136..356138,356331..356333))
                     /gene="fadE6"
                     /locus_tag="BCG_0309c"
                     /note="active site"
                     /db_xref="CDD:173838"
     misc_feature    complement(354315..355394)
                     /gene="fadE6"
                     /locus_tag="BCG_0309c"
                     /note="Putative acyl-CoA dehydrogenases similar to fadE6,
                     fadE17, and fadE26; Region: ACAD_fadE6_17_26; cd01152"
                     /db_xref="CDD:173841"
     misc_feature    complement(354300..355385)
                     /gene="fadE6"
                     /locus_tag="BCG_0309c"
                     /note="Acyl-CoA dehydrogenases [Lipid metabolism]; Region:
                     CaiA; COG1960"
                     /db_xref="CDD:224871"
     misc_feature    complement(order(354978..354980,354984..354986,
                     355056..355061,355074..355079,355083..355085))
                     /gene="fadE6"
                     /locus_tag="BCG_0309c"
                     /note="FAD binding site [chemical binding]; other site"
                     /db_xref="CDD:173841"
     misc_feature    complement(order(354327..354329,354360..354365,
                     354912..354914,355056..355058))
                     /gene="fadE6"
                     /locus_tag="BCG_0309c"
                     /note="substrate binding site [chemical binding]; other
                     site"
                     /db_xref="CDD:173841"
     misc_feature    complement(354729..354731)
                     /gene="fadE6"
                     /locus_tag="BCG_0309c"
                     /note="catalytic base [active]"
                     /db_xref="CDD:173841"
     gene            complement(356606..357739)
                     /locus_tag="BCG_0310c"
                     /db_xref="GeneID:4696257"
     CDS             complement(356606..357739)
                     /locus_tag="BCG_0310c"
                     /note="Differs from Mb0278c by 1aa, P164L"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_976408.1"
                     /db_xref="GI:121636185"
                     /db_xref="GeneID:4696257"
                     /translation="MTGRAATPGVIREFVGLPSRTAGRAAAGGHPCQGLYHHSVGRKP
                     KVALIAAHYQIDFSEHYLAEYMAIRGIGFLGWNTRFRGFESSFLLDHALVDIGVGVRW
                     LREVQGVETVVLLGNSGGGSLMAAYQSQAVDPNVTPLDGMRPAAGVTELPAADAYVAA
                     AAHPGRPDVLTAWMDAAVIDENDPVATDPELDLFDERNGPPYSPEFISRYRSAQVKRN
                     HTITDWAESELKRVRAAGFSDRPFSVMRTWADPRMVDPSIEPTKRRPNQCYAGTPVKA
                     NRSAHGIAAACTLRGWLGMWSLRVAQTRAAPHLARITCPALVLNAEADTGIFPSDAQQ
                     IYDGLASSDKTQVSIDTDHYFTTPGARSEQADTIAKWIAKRWR"
     misc_feature    complement(356627..>357085)
                     /locus_tag="BCG_0310c"
                     /note="Alpha/beta hydrolase family; Region: Abhydrolase_6;
                     pfam12697"
                     /db_xref="CDD:257231"
     gene            complement(357736..358356)
                     /locus_tag="BCG_0311c"
                     /db_xref="GeneID:4697726"
     CDS             complement(357736..358356)
                     /locus_tag="BCG_0311c"
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulatory protein"
                     /protein_id="YP_976409.1"
                     /db_xref="GI:121636186"
                     /db_xref="GeneID:4697726"
                     /translation="MPDFPTQRGRRTQAAIDAAARTVVVRNGILATTVADITAEAGRS
                     AASFYNYYDSKEAMVRQWALRFRDDANQRALSVIRHGLSDRERAYEAAAAHWYTYRNR
                     LAEAISVSQLAMVSDDFAQYWSEICQIPISFITETVKRAQAHGYCVGDDPQLMAEAIV
                     AMFNQFCYLQLSGKRSRRGQPDDQACIQTLANIYYRAIYSKEDSSN"
     misc_feature    complement(357868..358344)
                     /locus_tag="BCG_0311c"
                     /note="Transcriptional regulator [Transcription]; Region:
                     AcrR; COG1309"
                     /db_xref="CDD:224228"
     misc_feature    complement(358177..358305)
                     /locus_tag="BCG_0311c"
                     /note="Bacterial regulatory proteins, tetR family; Region:
                     TetR_N; pfam00440"
                     /db_xref="CDD:249860"
     gene            358453..359034
                     /locus_tag="BCG_0312"
                     /db_xref="GeneID:4697690"
     CDS             358453..359034
                     /locus_tag="BCG_0312"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_976410.1"
                     /db_xref="GI:121636187"
                     /db_xref="GeneID:4697690"
                     /translation="MIKPHNTNTEFELGGINHVALVCSDMARTVDFYSNILGMPLIKA
                     LDLPGGQGQHFFFDAGNGDCVAFFWFADAPDRVPGLSSPVAIPGIGDITSAVSTMNHL
                     AFHVPAERFDAYRQRLKDKGVRVGPVLNHDDSETQVSAVVHPGVYVRSFYFQDPDGIT
                     LEFACWTKEFTTSDAQAVPKTAADRRPPVAADR"
     misc_feature    358495..358944
                     /locus_tag="BCG_0312"
                     /note="N-terminal domain of Sphingobium chlorophenolicum
                     2,6-dichloro-p-hydroquinone 1,2-dioxygenase (PcpA), and
                     similar proteins; Region: PcpA_N_like; cd08346"
                     /db_xref="CDD:211356"
     misc_feature    order(358504..358506,358510..358512)
                     /locus_tag="BCG_0312"
                     /note="Zn binding site [ion binding]; other site"
                     /db_xref="CDD:211356"
     gene            complement(358964..359689)
                     /locus_tag="BCG_0313c"
                     /db_xref="GeneID:4699312"
     CDS             complement(358964..359689)
                     /locus_tag="BCG_0313c"
                     /note="Differs from Rv0275c by 1aa, L24S"
                     /codon_start=1
                     /transl_table=11
                     /product="TetR family transcriptional regulator"
                     /protein_id="YP_976411.1"
                     /db_xref="GI:121636188"
                     /db_xref="GeneID:4699312"
                     /translation="MTRSDRPYRGVEAAERLATRRRQLLSAGLDLLGSDQHDIAELTI
                     RTICRRAGLSVRYFYESFTDKDEFVGRVFDWVVAELVATTQAAVTAVPAREQTRAGMA
                     NIVRTITADARVGRLLFSTQLANAVITRKRAESSALFAMLSGQHAVDTLHAPANDHVK
                     AVAHFAVGGVGQTISAWLAGDVRLDPDQLVDQLAALLDELTDPNLSRPRVAATAAKSG
                     ANDPQPPEVAGQPPSSARPARRS"
     misc_feature    complement(359087..359647)
                     /locus_tag="BCG_0313c"
                     /note="Transcriptional regulator [Transcription]; Region:
                     AcrR; COG1309"
                     /db_xref="CDD:224228"
     misc_feature    complement(359474..359620)
                     /locus_tag="BCG_0313c"
                     /note="Bacterial regulatory proteins, tetR family; Region:
                     TetR_N; cl19382"
                     /db_xref="CDD:267735"
     gene            359779..360699
                     /locus_tag="BCG_0314"
                     /db_xref="GeneID:4697725"
     CDS             359779..360699
                     /locus_tag="BCG_0314"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_976412.1"
                     /db_xref="GI:121636189"
                     /db_xref="GeneID:4697725"
                     /translation="MAISLVAHQPIPHVERPMADPPRLQLARRRRSAAGPGGNEDSLM
                     GVALLAGPANVIMELAMPGVGYGVLESRVESGRLDRHPIKRARTTFTYVAVAVAGSDD
                     QKAAFRRAVNKVHAQVYSTPESPVSYHAFDPELQLWVAACLYKGGVDVYRTFVGEMDD
                     EEADHHYRAGMAMGTTLQVPPQMWPPDRAAFDRYWRQSLDRVHIDDVVRDYLYPIVAL
                     RIRGIALPGPLRRLSEGIALLITTGFLPQRFRDEMRLPWDATKQRRFDALMAVLRTVN
                     RLMPRFVREFPFNLMLWDLDRRMRRGRPLV"
     misc_feature    359779..360696
                     /locus_tag="BCG_0314"
                     /note="Uncharacterized protein conserved in bacteria
                     [Function unknown]; Region: COG3662"
                     /db_xref="CDD:226188"
     gene            complement(360739..361167)
                     /locus_tag="BCG_0315c"
                     /db_xref="GeneID:4696359"
     CDS             complement(360739..361167)
                     /locus_tag="BCG_0315c"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_976413.1"
                     /db_xref="GI:121636190"
                     /db_xref="GeneID:4696359"
                     /translation="MFLIDVNVLLAAHRGDHPNHRTVRPWFDRLLAADDPFTVPNLVW
                     ASFLRLTTNRRIFEIPSPRADAFAFVEAVNAQPHHLPTSPGPRHLVLLRKLCDEADAS
                     GDLIPDAVLGAIAVEHHCAVVSLDRDFARFASVRHIRPPI"
     misc_feature    complement(360745..361167)
                     /locus_tag="BCG_0315c"
                     /note="Mycobacterium tuberculosis PIN domain family;
                     Region: Mtu_PIN_fam; TIGR00028"
                     /db_xref="CDD:232790"
     misc_feature    complement(order(360790..360792,360844..360846,
                     361153..361155))
                     /locus_tag="BCG_0315c"
                     /note="putative active site [active]"
                     /db_xref="CDD:189022"
     gene            complement(361191..361448)
                     /locus_tag="BCG_0315A"
                     /db_xref="GeneID:4697964"
     CDS             complement(361191..361448)
                     /locus_tag="BCG_0315A"
                     /note="Differs by 1 aa, Q24* from Rv0227A and Mb0351A"
                     /codon_start=1
                     /transl_table=11
                     /product="antitoxin"
                     /protein_id="YP_976414.1"
                     /db_xref="GI:121636191"
                     /db_xref="GeneID:4697964"
                     /translation="MRTTVSISDELLATAKRRARERGQSLGAVIEDALRRELAAARTG
                     GARPTVPVFDAGTGPRPGIDLTSNRVLSEVLDEGLELNSRK"
     misc_feature    complement(361344..361445)
                     /locus_tag="BCG_0315A"
                     /note="Ribbon-helix-helix protein, copG family; Region:
                     RHH_1; pfam01402"
                     /db_xref="CDD:250592"
     gene            complement(361468..361710)
                     /gene="PE_PGRS3b"
                     /locus_tag="BCG_0316c"
                     /pseudo
                     /db_xref="GeneID:4695664"
     gene            complement(361533..364283)
                     /gene="PE_PGRS3a"
                     /locus_tag="BCG_0317c"
                     /db_xref="GeneID:4697094"
     CDS             complement(361533..364283)
                     /gene="PE_PGRS3a"
                     /locus_tag="BCG_0317c"
                     /note="In Mycobacterium tuberculosis strain H37Rv,
                     PE_PGRS3 exists as a single gene. In Mycobacterium bovis
                     and Mycobacterium bovs BCG Pasteur, a large insertion
                     leads to an extra copy of PE_PGRS3. Also, a frameshift due
                     to single base deletion (t-*), splits this extra copy of
                     PE_PGRS3 into 2 parts, PE_PGRS3a and PE_PGRS3b. Also
                     differs from Mb0285c by an insertion of 144bp"
                     /codon_start=1
                     /transl_table=11
                     /product="PE-PGRS family protein"
                     /protein_id="YP_976415.1"
                     /db_xref="GI:121636192"
                     /db_xref="GeneID:4697094"
                     /translation="MSFVIAAPEVIAAAATDLASLESSIAAANAAAAANTTALLAAGA
                     DEVSTAVAALFGAHGQAYQALSAQAQAFHAQFTQALTSGGGAYAAAEAAATSPLLAPI
                     NEFFLANTGRPLIGNGANGAPGTGADGAPGGWLIGNGGAGGSGAANNAVGGTGGTGGA
                     GGASGLLGSGGAGGAGGVATNTGGIGGAGGTGGNAVLFGAGGAGGASTNTTGGAGGAG
                     GDGGNAGLLFGAAGVGGAGGFALATTASGGAGGAGGAGGMFTDGGVGGVGGKGGFGGA
                     GGAGGNGGLFGAGGTGGAGGTIGAGVAGMGGAGGAGGAGGLFGAGGTGGSGGGGATTG
                     GDGGAGGNAGTLSLGAAGGAGGAGGEGLASAGGDGGAGGDGGNAGMFFGSGGAGGAGG
                     FGRTTGGIGGTGGNAGLLNGSGGAGGAGGAAITGPGGTGGAGGIPGLIGNGGNGGDGG
                     ASVTGTGGNGGAGGNGVQIGNGGNGGSGGTGAAAGKAGLGGLGGQLIGLDGSNAPVST
                     SVHTLQQAALNVVNEPFQTLTGRPLIGNGANGTPGTGAAGGAGGWLFGNGGNGGHGAT
                     NTAATATGGAGGAGGILFGTGGNGGTGGIATGAGGIGGAGGAGGVSLLIGSGGTGGNG
                     GNSIGVAGIGGAGGRGGDAGLLFGAAGTGGHGAAGGVPAGVGGAGGNGGLFANGGAGG
                     AGGFNAAGGNGGNGGLFGTGGTGGAGTNFGAGGNGGNGGLFGAGGTGGAAGSGGSGIT
                     TGGGGHGGNAGLLSLGASGGAGGSGGASSLAGGAGGTGGNGALLFGFGGAGGAGGHGG
                     AALTSIQQGGAGGAGGNGGLLFGSAGAGGAGGSGANALGAGTGGTGGDGGHAGVFGNG
                     GDGGAGGFGAGTGGSGGVGGNAVLIGNGGNGGNAGKAGATPGAGGTGGLLLGENGLNG
                     LP"
     misc_feature    complement(364038..364283)
                     /gene="PE_PGRS3a"
                     /locus_tag="BCG_0317c"
                     /note="PE family; Region: PE; pfam00934"
                     /db_xref="CDD:250239"
     misc_feature    362672..365595
                     /note="I-RD01, 2924 bp. Region of Difference I-RDXXXX,
                     inserted region in Mycobacterium bovis BCG Pasteur
                     (position 362672..365595, 2924bp) and Mycobacterium bovis
                     AF2122/97 (position 332966..335745, 2780 bp) compared to
                     Mycobacterium tuberculosis H37Rv2 (position:
                     334641..334642). Duplicates PE_PGRS3"
     gene            complement(364547..367246)
                     /gene="PE_PGRS3"
                     /locus_tag="BCG_0318c"
                     /db_xref="GeneID:4697093"
     CDS             complement(364547..367246)
                     /gene="PE_PGRS3"
                     /locus_tag="BCG_0318c"
                     /note="In Mycobacterium bovis BCG Pasteur, a insertion of
                     66 bp lead to a longer product than to the homolog
                     Mycobacterium bovis (899 aa versus 877 aa). In
                     Mycobacterium bovis, 2 deletions, one of 18 bp and the
                     other of 66 bp, and part of a 2780 bp insertion , leads to
                     a shorter product with a different 3' end compared to its
                     homolog in Mycobacterium tuberculosis strain H37Rv (877 aa
                     versus 957 aa)"
                     /codon_start=1
                     /transl_table=11
                     /product="PE-PGRS family protein"
                     /protein_id="YP_976416.1"
                     /db_xref="GI:121636193"
                     /db_xref="GeneID:4697093"
                     /translation="MSFVIAAPEVIAAAATDLASLGSSISAANAAAAANTTALMAAGA
                     DEVSTAIAALFGAHGQAYQALSAQAQAFHAQFVQALTSGGGAYAAAEAAAVSPLLDPI
                     NEFFLANTGRPLIGNGANGAPGTGANGGDGGWLIGNGGAGGSGAAGVNGGAGGNGGAG
                     GLIGNGGAGGAGGVASSGIGGSGGAGGNAMLFGAGGAGGAGGGVVALTGGAGGAGGAG
                     GNAGLLFGAAGVGGAGGFTNGSALGGAGGAGGAGGLFATGGVGGSGGAGSSGGAGGAG
                     GAGGLFGAGGTGGHGGFADSSFGGVGGAGGAGGLFGAGGEGGSGGHSLVAGGDGGAGG
                     NAGMLALGAAGGAGGIGGDGGTLTAGGIGGAGGAGGNAGLLFGSGGSGGAGGFGFADG
                     GQGGPGGNAGTVFGSGGAGGNGGVGQGFAGGIGGAGGTPGLIGNGGNGGNGGASAVTG
                     GNGGIGGTGVLIGNGGNGGSGGIGAGKAGVGGVSGLLLGLDGFNAPASTSPLHTLQQN
                     VLNVVNEPFQTLTGRPLIGNGANGTPGTGADGGAGGWLFGNGGNGGSGATGTNGGDGG
                     DGGAGGIFFGTGGTGGAGGVGTTGTGGDGGAGGAAFLVGSGGNGGSGGAGLTAGGDGG
                     DGGNAGSFFGAAGTGGAGASTKAGGTGGTGGNGGLFANGGAGGSGGLGGDAGTGGAGG
                     NGGLFGAGGTGGAGGSLGPGAGGAGGNGGLFGAGGTGGSGGHGTPAAVPGGAGGAGGN
                     AGLFSLGASGGAGGSGGSSLTDSGGIGGVGGAGGLLFGYGGAGGAGGYSNIGAGGAGG
                     AGGNAGMLSGSGGSGGTGGASGAAKGGVGGNGGTAGVFGNGGDGGAGGFGAGTGGNGG
                     VGGNAVLIGNGGNGGNGGKAGGTPGAGGTSGLLIGENGLNGLP"
     misc_feature    complement(367001..367246)
                     /gene="PE_PGRS3"
                     /locus_tag="BCG_0318c"
                     /note="PE family; Region: PE; pfam00934"
                     /db_xref="CDD:250239"
     gene            complement(367496..370000)
                     /gene="PE_PGRS4"
                     /locus_tag="BCG_0319c"
                     /db_xref="GeneID:4696182"
     CDS             complement(367496..370000)
                     /gene="PE_PGRS4"
                     /locus_tag="BCG_0319c"
                     /note="In Mycobacterium bovis BCG Pasteur, 2 insertions
                     each of 9 bp and a deletion of 9bp, lead to a longer
                     product compared to its homolog in Mycobacterium bovis
                     (834 aa versus 831 aa). In Mycobacterium bovis, 2
                     deletions each of 9 bp (ccgccggcg-* and cccgccggc-*),
                     leads to a shorter product compared to its homolog in
                     Mycobacterium tuberculosis strain H37Rv (831 aa versus 837
                     aa)"
                     /codon_start=1
                     /transl_table=11
                     /product="PE-PGRS family protein"
                     /protein_id="YP_976417.1"
                     /db_xref="GI:121636194"
                     /db_xref="GeneID:4696182"
                     /translation="MSFVIAAPEVIAAAATDLASLESSIAAANAAAAANTTALLAAGA
                     DEVSTAVAALFGAHGQAYQALSAQAQAFHAQFVQALTSGGGAYAAAEAAATSPLLAPI
                     NEFFLANTGRPLIGNGANGAPGTGADGAPGGWLIGNGGAGGSGAAGVNGGAGGNGGAG
                     GLIGNGGAGGAGGRASTGTGGAGGAGGAAGMLFGAAGVGGPGGFAAAFGATGGAGGAG
                     GNGGLFADGGVGGAGGATDAGTGGAGGSGGNGGLFGAGGTGGPGGFGIFGGGAGGDGG
                     SGGLFGAGGTGGSGGTSIINVGGNGGAGGDAGMLSLGAAGGAGGSGGSSPDGGGGAGG
                     IGGDGGTLFGSGGVGGLGFDAGGAGGAGGKAGLLSGAGGAGGAGGGSFAGAGGTGGAG
                     GAPGLVGNAGNGGNGGASANGAGAAGGAGGSGVLIGNGGNGGSGGTGAPAGTAGAGGL
                     GGQLLGRDGFNAPASTPLHTLQQQILNAINEPTQALTGRPLIGNGANGTPGTGADGGA
                     GGWLFGNGGNGGHGATGADGGDGGSGGAGGILSGIGGTGGSGGIGTTGQGGTGGTGGA
                     ALLIGSGGTGGSGGFGLDTGGAGGRGGDAGLFLGAAGTGGQAALSQNFIGAGGTAGAG
                     GTGGLFANGGAGGAGGFGANGGTGGNGLLFGAGGTGGAGTLGADGGAGGHGGLFGAGG
                     TGGAGGSSGGTFGGNGGSGGNAGLLALGASGGAGGSGGSALNVGGTGGVGGNGGSGGS
                     LFGFGGAGGTGGSSGIGSSGGTGGDGGTAGVFGNGGDGGAGGFGTGAGGTGGTGGNAV
                     LIGNGGNGGNGGKAGGTPGAGGTSGLIIGENGLNGL"
     misc_feature    complement(369755..370000)
                     /gene="PE_PGRS4"
                     /locus_tag="BCG_0319c"
                     /note="PE family; Region: PE; pfam00934"
                     /db_xref="CDD:250239"
     gene            370291..371901
                     /gene="PPE3"
                     /locus_tag="BCG_0320"
                     /db_xref="GeneID:4697095"
     CDS             370291..371901
                     /gene="PPE3"
                     /locus_tag="BCG_0320"
                     /note="Differs from Rv0280 by 1 aa P337S"
                     /codon_start=1
                     /transl_table=11
                     /product="PPE family protein"
                     /protein_id="YP_976418.1"
                     /db_xref="GI:121636195"
                     /db_xref="GeneID:4697095"
                     /translation="MTLWMASPPEVHSALLSSGPGPGSVLSAAGVWSSLSAEYAAVAD
                     ELIGLLGAVQTGAWQGPSAAAYVAAHAPYLAWLMRASETSAEAAARHETVAAAYTTAV
                     AAMPTLVELAANHTLHGVLVATNFFGINTIPIALNEADYARMWTQAASTMATYQAVAE
                     AAVASAPQTTPAPPILAAEAADDDHDHDHDHGGEPTPLDYLVAEILRIISGGRLIWDP
                     AEGTMNGIPFEDYTDAAQPIWWVVRAIEFSKDFETFVQELFVNPVEAFQFYFELLLFD
                     YPTHIVQIVEALSQSPQLLAVALGSVISNLGAVTGFAGLSGLAGMQPAAIPALAPVAA
                     APPTLPAVAMAPTMAAPGAAVASAAAPASAPAASTVASATPAPPPAPGAAGFGYPYAI
                     APPGIGFGSGMSASASAQRKAPQPDSAAAAAAAAAVRDQARARRRRRVTRRGYGDEFM
                     DMNIDVDPDWGPPPGEDPVTSTVASDRGAGHLGFAGTARREAVADAAGMTTLAGDDFG
                     DGPTTPMVPGSWDPDRDAPGSAEPGDRG"
     misc_feature    370300..371862
                     /gene="PPE3"
                     /locus_tag="BCG_0320"
                     /note="PPE-repeat proteins [Cell motility and secretion];
                     Region: COG5651"
                     /db_xref="CDD:227938"
     misc_feature    370306..370758
                     /gene="PPE3"
                     /locus_tag="BCG_0320"
                     /note="PPE family; Region: PPE; pfam00823"
                     /db_xref="CDD:250158"
     gene            371925..372833
                     /locus_tag="BCG_0321"
                     /db_xref="GeneID:4697685"
     CDS             371925..372833
                     /locus_tag="BCG_0321"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_976419.1"
                     /db_xref="GI:121636196"
                     /db_xref="GeneID:4697685"
                     /translation="MRTEGDSWDITTSVGSTALFVATARALEAQKSDPLVVDPYAEAF
                     CRAVGGSWADVLDGKLPDHKLKSTDFGEHFVNFQGARTKYFDEYFRRAAAAGARQVVI
                     LAAGLDSRAYRLPWPDGTTVFELDRPQVLDFKREVLASHGAQPRALRREIAVDLRDDW
                     PQALRDSGFDAAAPSAWIAEGLLIYLPATAQERLFTGIDALAGRRSHVAVEDGAPMGP
                     DEYAAKVEEERAAIAEGAEEHPFFQLVYNERCAPAAEWFGERGWTAVATLLNDYLEAV
                     GRPVPGPESEAGPMFARNTLVSAARV"
     misc_feature    371925..372827
                     /locus_tag="BCG_0321"
                     /note="O-Methyltransferase involved in polyketide
                     biosynthesis [Secondary metabolites biosynthesis,
                     transport, and catabolism]; Region: COG3315"
                     /db_xref="CDD:225852"
     gene            373058..374953
                     /locus_tag="BCG_0322"
                     /db_xref="GeneID:4697218"
     CDS             373058..374953
                     /locus_tag="BCG_0322"
                     /note="Differs from Rv0282 by 1aa, A6E"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_976420.1"
                     /db_xref="GI:121636197"
                     /db_xref="GeneID:4697218"
                     /translation="MAGVGAGDSGGVERDDIGMVAASPVASRVNGKVDADVVGRFATC
                     CRALGIAVYQRKRPPDLAAARSGFAALTRVAHDQCDAWTGLAAAGDQSIGVLEAASRT
                     ATTAGVLQRQVELADNALGFLYDTGLYLRFRATGPDDFHLAYAAALASTGGPEEFAKA
                     NHVVSGITERRAGWRAARWLAVVINYRAERWSDVVKLLTPMVNDPDLDEAFSHAAKIT
                     LGTALARLGMFAPALSYLEEPDGPVAVAAVDGALAKALVLRAHVDEESASEVLQDLYA
                     AHPENEQVEQALSDTSFGIVTTTAGRIEARTDPWDPATEPGAEDFVDPAAHERKAALL
                     HEAELQLAEFIGLDEVKRQVSRLKSSVAMELVRKQRGLTVAQRTHHLVFAGPPGTGKT
                     TIARVVAKIYCGLGLLKRENIREVHRADLIGQHIGETEAKTNAIIDSALDGVLFLDEA
                     YALVATGAKNDFGLVAIDTLLARMENDRDRLVVIIAGYRADLDKFLDTNEGLRSRFTR
                     NIDFPSYTSHELVEIAHKMAEQRDSVFEQSALHDLEALFAKLAAESTPDTNGISRRSL
                     DIAGNGRFVRNIVERSEEEREFRLDHSEHAGSGEFSDEELMTITADDVGRSVEPLLRG
                     LGLSVRA"
     misc_feature    373259..374926
                     /locus_tag="BCG_0322"
                     /note="type VII secretion AAA-ATPase EccA; Region:
                     T7SS_EccA; TIGR03922"
                     /db_xref="CDD:188437"
     misc_feature    374015..>374257
                     /locus_tag="BCG_0322"
                     /note="The AAA+ (ATPases Associated with a wide variety of
                     cellular Activities) superfamily represents an ancient
                     group of ATPases belonging to the ASCE (for additional
                     strand, catalytic E) division of the P-loop NTPase fold.
                     The ASCE division also includes ABC; Region: AAA; cl18944"
                     /db_xref="CDD:267297"
     misc_feature    374138..374599
                     /locus_tag="BCG_0322"
                     /note="The AAA+ (ATPases Associated with a wide variety of
                     cellular Activities) superfamily represents an ancient
                     group of ATPases belonging to the ASCE (for additional
                     strand, catalytic E) division of the P-loop NTPase fold.
                     The ASCE division also includes ABC; Region: AAA; cd00009"
                     /db_xref="CDD:99707"
     misc_feature    374210..374233
                     /locus_tag="BCG_0322"
                     /note="Walker A motif; other site"
                     /db_xref="CDD:99707"
     misc_feature    order(374213..374236,374399..374401,374519..374521)
                     /locus_tag="BCG_0322"
                     /note="ATP binding site [chemical binding]; other site"
                     /db_xref="CDD:99707"
     misc_feature    374387..374404
                     /locus_tag="BCG_0322"
                     /note="Walker B motif; other site"
                     /db_xref="CDD:99707"
     misc_feature    374570..374572
                     /locus_tag="BCG_0322"
                     /note="arginine finger; other site"
                     /db_xref="CDD:99707"
     gene            374950..376566
                     /locus_tag="BCG_0323"
                     /db_xref="GeneID:4697294"
     CDS             374950..376566
                     /locus_tag="BCG_0323"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_976421.1"
                     /db_xref="GI:121636198"
                     /db_xref="GeneID:4697294"
                     /translation="MTNQQHDHDFDHDRRSFASRTPVNNNPDKVVYRRGFVTRHQVTG
                     WRFVMRRIAAGIALHDTRMLVDPLRTQSRAVLMGVLIVITGLIGSFVFSLIRPNGQAG
                     SNAVLADRSTAALYVRVGEQLHPVLNLTSARLIVGRPVSPTTVKSTELDQFPRGNLIG
                     IPGAPERMVQNTSTDANWTVCDGLNAPSRGGADGVGVTVIAGPLEDTGARAAALGPGQ
                     AVLVDSGAGTWLLWDGKRSPIDLADHAVTSGLGLGADVPAPRIIASGLFNAIPEAPPL
                     TAPIIPDAGNPASFGVPAPIGAVVSSYALKDSGKTISDTVQYYAVLPDGLQQISPVLA
                     AILRNNNSYGLQQPPRLGADEVAKLPVSRVLDTRRYPSEPVSLVDVTRDPVTCAYWSK
                     PVGAATSSLTLLAGSALPVPDAVHTVELVGAGNGGVATRVALAAGTGYFTQTVGGGPD
                     APGAGSLFWVSDTGVRYGIDNEPQGVAGGGKAVEALGLNPPPVPIPWSVLSLFVPGPT
                     LSRADALLAHDTLVPDSRPARPVSAEGGYR"
     misc_feature    375043..376524
                     /locus_tag="BCG_0323"
                     /note="Protein of unknown function (DUF690); Region:
                     DUF690; pfam05108"
                     /db_xref="CDD:253013"
     gene            376563..380555
                     /locus_tag="BCG_0324"
                     /db_xref="GeneID:4696654"
     CDS             376563..380555
                     /locus_tag="BCG_0324"
                     /note="Differs from Mb0292 by 1aa, A134T, and from Rv0284
                     by 2aa, A134T, R214P"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_976422.1"
                     /db_xref="GI:121636199"
                     /db_xref="GeneID:4696654"
                     /translation="MSRLIFEARRRLAPPSSHQGTIIIEAPPELPRVIPPSLLRRALP
                     YLIGILIVGMIVALVATGMRVISPQTLFFPFVLLLAATALYRGNDKKMRTEEVDAERA
                     DYLRYLSVVRDNIRAQAAEQRASALWSHPDPAALASVPGSRRQWERDPHDPDFLVLRA
                     GRHTVPLATTLRVNDTADEIDLEPVSHSALRSLLDTQRSIGDVPTGIDLTKVSRITVL
                     GERAQVRAVLRAWIAQAVTWHDPTVLGVALAARDLEGRDWNWLKWLPHVDIPGRLDAL
                     GPARNLSTDPDELIALLGPVLADRPAFTGQPTDALRHLLIVVDDPDYDLGASPLAVGR
                     AGVTVVHCSASAPHREQYSDPEKPILRVAHGAIERWQTGGWQPYIDAADQFSADEAAH
                     LARRLSRWDSNPTHAGLRSAATRGASFTTLLGIEDASRLDVPALWAPRRRDEELRVPI
                     GVTGTGEPLMFDLKDEAEGGMGPHGLMIGMTGSGKSQTLMSILLSLLTTHSAERLIVI
                     YADFKGEAGADSFRDFPQVVAVISNMAEKKSLADRFADTLRGEVARREMLLREAGRKV
                     QGSAFNSVLEYENAIAAGHSLPPIPTLFVVADEFTLMLADHPEYAELFDYVARKGRSF
                     RIHILFASQTLDVGKIKDIDKNTAYRIGLKVASPSVSRQIIGVEDAYHIESGKEHKGV
                     GFLVPAPGATPIRFRSTYVDGIYEPPQTAKAVVVQSVPEPKLFTAAAVEPDPGTVIAD
                     TDEQEPADPPRKLIATIGEQLARYGPRAPQLWLPPLDETIPLSAALARAGVGPRQWRW
                     PLGEIDRPFEMRRDPLVFDARSSAGNMVIHGGPKSGKSTALQTFILSAASLHSPHEVS
                     FYCLDYGGGQLRALQDLAHVGSVASALEPERIRRTFGELEQLLLSRQQREVFRDRGAN
                     GSTPDDGFGEVFLVIDNLYGFGRDNTDQFNTRNPLLARVTELVNVGLAYGIHVIITTP
                     SWLEVPLAMRDGLGLRLELRLHDARDSNVRVVGALRRPADAVPHDQPGRGLTMAAEHF
                     LFAAPELDAQTNPVAAINARYPGMAAPPVRLLPTNLAPHAVGELYRGPDQLVIGQREE
                     DLAPVILDLAANPLLMVFGDARSGKTTLLRHIIRTVREHSTADRVAFTVLDRRLHLVD
                     EPLFPDNEYTANIDRIIPAMLGLANLIEARRPPAGMSAAELSRWTFAGHTHYLIIDDV
                     DQVPDSPAMTGPYIGQRPWTPLIGLLAQAGDLGLRVIVTGRATGSAHLLMTSPLLRRF
                     NDLQATTLMLAGNPADSGKIRGERFARLPAGRAILLTDSDSPTYVQLINPLVDAAAVS
                     GETQQKGSQS"
     misc_feature    376668..378677
                     /locus_tag="BCG_0324"
                     /note="type VII secretion protein EccCa; Region:
                     T7SS_EccC_a; TIGR03924"
                     /db_xref="CDD:234400"
     misc_feature    377880..378473
                     /locus_tag="BCG_0324"
                     /note="FtsK/SpoIIIE family; Region: FtsK_SpoIIIE;
                     pfam01580"
                     /db_xref="CDD:250719"
     misc_feature    378816..380489
                     /locus_tag="BCG_0324"
                     /note="type VII secretion protein EccCb; Region:
                     T7SS_EccC_b; TIGR03925"
                     /db_xref="CDD:234401"
     misc_feature    378912..379664
                     /locus_tag="BCG_0324"
                     /note="FtsK/SpoIIIE family; Region: FtsK_SpoIIIE;
                     pfam01580"
                     /db_xref="CDD:250719"
     misc_feature    379794..>379979
                     /locus_tag="BCG_0324"
                     /note="FtsK/SpoIIIE family; Region: FtsK_SpoIIIE;
                     pfam01580"
                     /db_xref="CDD:250719"
     gene            380552..380860
                     /gene="PE5"
                     /locus_tag="BCG_0325"
                     /db_xref="GeneID:4698280"
     CDS             380552..380860
                     /gene="PE5"
                     /locus_tag="BCG_0325"
                     /codon_start=1
                     /transl_table=11
                     /product="PE family protein"
                     /protein_id="YP_976423.1"
                     /db_xref="GI:121636200"
                     /db_xref="GeneID:4698280"
                     /translation="MTLRVVPEGLAAASAAVEALTARLAAAHASAAPVITAVVPPAAD
                     PVSLQTAAGFSAQGVEHAVVTAEGVEELGRAGVGVGESGASYLAGDAAAAATYGVVGG
                     "
     misc_feature    380558..380821
                     /gene="PE5"
                     /locus_tag="BCG_0325"
                     /note="PE family; Region: PE; pfam00934"
                     /db_xref="CDD:250239"
     gene            380863..382404
                     /gene="PPE4"
                     /locus_tag="BCG_0326"
                     /db_xref="GeneID:4696202"
     CDS             380863..382404
                     /gene="PPE4"
                     /locus_tag="BCG_0326"
                     /codon_start=1
                     /transl_table=11
                     /product="PPE family protein"
                     /protein_id="YP_976424.1"
                     /db_xref="GI:121636201"
                     /db_xref="GeneID:4696202"
                     /translation="MAAPIWMASPPEVHSALLSNGPGPGSLVAAATAWSQLSAEYAST
                     AAELSGLLGAVPGWAWQGPSAEWYVAAHLPYVAWLTQASADAAGAAAQHEAAAAAYTT
                     ALAAMPTLAELAANHVIHTVLVATNFFGINTIPITLNEADYVRMWLQAAAVMGLYQAA
                     SGAALASAPRTVPAPTVMNPGGGAASTVGAVNPWQWLLALLQQLWNAYTGFYGWMLQL
                     IWQFLQDPIGNSIKIIIAFLTNPIQALITYGPLLFALGYQIFFNLVGWPTWGMILSSP
                     FLLPAGLGLGLAAIAFLPIVLAPAVIPPASTPLAAAAVAAGSVWPAVSMAVTGAGTAG
                     AATPAAGAAPSAGAAPAPAAPATASFAYAVGGSGDWGPSLGPTVGGRGGIKAPAATVP
                     AAAAAAATRGQSRARRRRRSELRDYGDEFLDMDSDSGFGPSTGDHGAQASERGAGTLG
                     FAGTATKERRVRAVGLTALAGDEFGNGPRMPMVPGTWEQGSNEPEAPDGSGRGGGDGL
                     PHDSK"
     misc_feature    380872..382335
                     /gene="PPE4"
                     /locus_tag="BCG_0326"
                     /note="PPE-repeat proteins [Cell motility and secretion];
                     Region: COG5651"
                     /db_xref="CDD:227938"
     misc_feature    380884..381336
                     /gene="PPE4"
                     /locus_tag="BCG_0326"
                     /note="PPE family; Region: PPE; pfam00823"
                     /db_xref="CDD:250158"
     gene            382453..382746
                     /gene="esxG"
                     /locus_tag="BCG_0327"
                     /db_xref="GeneID:4697818"
     CDS             382453..382746
                     /gene="esxG"
                     /locus_tag="BCG_0327"
                     /standard_name="TB9.8"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_976425.1"
                     /db_xref="GI:121636202"
                     /db_xref="GeneID:4697818"
                     /translation="MSLLDAHIPQLVASQSAFAAKAGLMRHTIGQAEQAAMSAQAFHQ
                     GESSAAFQAAHARFVAAAAKVNTLLDVAQANLGEAAGTYVAADAAAASTYTGF"
     gene            382776..383066
                     /gene="esxH"
                     /locus_tag="BCG_0328"
                     /db_xref="GeneID:4698781"
     CDS             382776..383066
                     /gene="esxH"
                     /locus_tag="BCG_0328"
                     /standard_name="cfp7; TB10.4"
                     /codon_start=1
                     /transl_table=11
                     /product="low molecular weight protein antigen 7 cfp7"
                     /protein_id="YP_976426.1"
                     /db_xref="GI:121636203"
                     /db_xref="GeneID:4698781"
                     /translation="MSQIMYNYPAMLGHAGDMAGYAGTLQSLGAEIAVEQAALQSAWQ
                     GDTGITYQAWQAQWNQAMEDLVRAYHAMSSTHEANTMAMMARDTAEAAKWGG"
     misc_feature    382776..383063
                     /gene="esxH"
                     /locus_tag="BCG_0328"
                     /note="Uncharacterized protein conserved in bacteria
                     [Function unknown]; Region: COG4842"
                     /db_xref="CDD:227179"
     gene            383077..383964
                     /locus_tag="BCG_0329"
                     /db_xref="GeneID:4698809"
     CDS             383077..383964
                     /locus_tag="BCG_0329"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_976427.1"
                     /db_xref="GI:121636204"
                     /db_xref="GeneID:4698809"
                     /translation="MDATPNAVELTVDNAWFIAETIGAGTFPWVLAITMPYSDAAQRG
                     AFVDRQRDELTRMGLLSPQGVINPAVADWIKVVCFPDRWLDLRYVGPASADGACELLR
                     GIVALRTGTGKTSNKTGNGVVALRNAQLVTFTAMDIDDPRALVPILGVGLAHRPPARF
                     DEFSLPTRVGARADERLRSGVPLGEVVDYLGIPASARPVVESVFSGPRSYVEIVAGCN
                     RDGRHTTTEVGLSIVDTSAGRVLVSPSRAFDGEWVSTFSPGTPFAIAVAIQTLTACLP
                     DGQWFPGQRVSRDFSTQSS"
     misc_feature    383104..383889
                     /locus_tag="BCG_0329"
                     /note="EspG family; Region: ESX-1_EspG; pfam14011"
                     /db_xref="CDD:258246"
     gene            384011..385429
                     /locus_tag="BCG_0330"
                     /db_xref="GeneID:4698139"
     CDS             384011..385429
                     /locus_tag="BCG_0330"
                     /note="Differs from Rv0290 by 1aa, T400A"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_976428.1"
                     /db_xref="GI:121636205"
                     /db_xref="GeneID:4698139"
                     /translation="MSGTVMQIVRVAILADSRLTEMALPAELPLREILPAVQRLVVPS
                     AQNGDGGQADSGAAVQLSLAPVGGQPFSLDASLDTVGVVDGDLLVLQPVPAGPAAPGI
                     VEDIADAAMIFSTSRLKPWGIAHIQRGALAAVIAVALLATGLTVTYRVATGVLAGLLA
                     VAGIAVASALAGLLITIRSPRSGIALSIAALVPIGAALALAVPGKFGPAQVLLGAAGV
                     AAWSLIALMIPSAERERVVAFFTAAAVVGASVALAAGAQLLWQLPLLSIGCGLIVAAL
                     LVTIQAAQLSALWARFPLPVIPAPGDPTPSAPPLRLLEDLPRRVRVSDAHQSGFIAAA
                     VLLSVLGSVAIAVRPEALSVVGWYLVAATAAAATLRARVWDSAACKAWLLAQPYLVAG
                     VLLVFYTTTGRYVAAFGAVLVLAVLMLAWVVVALNPGIASPESYSLPLRRLLGLVAAG
                     LDVSLIPVMAYLVGLFAWVLNR"
     misc_feature    384041..385360
                     /locus_tag="BCG_0330"
                     /note="type VII secretion integral membrane protein EccD;
                     Region: T7SS_EccD; TIGR03920"
                     /db_xref="CDD:234397"
     gene            385426..386811
                     /locus_tag="BCG_0331"
                     /db_xref="GeneID:4699096"
     CDS             385426..386811
                     /locus_tag="BCG_0331"
                     /EC_number="3.4.-.-"
                     /codon_start=1
                     /transl_table=11
                     /product="protease"
                     /protein_id="YP_976429.1"
                     /db_xref="GI:121636206"
                     /db_xref="GeneID:4699096"
                     /translation="MIRAAFACLAATVVVAGWWTPPAWAIGPPVVDAAAQPPSGDPGP
                     VAPMEQRGACSVSGVIPGTDPGVPTPSQTMLNLPAAWQFSRGEGQLVAIIDTGVQPGP
                     RLPNVDAGGDFVESTDGLTDCDGHGTLVAGIVAGQPGNDGFSGVAPAARLLSIRAMST
                     KFSPRTSGGDPQLAQATLDVAVLAGAIVHAADLGAKVINVSTITCLPADRMVDQAALG
                     AAIRYAAVDKDAVIVAAAGNTGASGSVSASCDSNPLTDLSRPDDPRNWAGVTSVSIPS
                     WWQPYVLSVASLTSAGQPSKFSMPGPWVGIAAPGENIASVSNSGDGALANGLPDAHQK
                     LVALSGTSYAAGYVSGVAALVRSRYPGLNATEVVRRLTATAHRGARESSNIVGAGNLD
                     AVAALTWQLPAEPGGGAAPAKPVADPPVPAPKDTTPRNVAFAGAAALSVLVGLTAATV
                     AIARRRREPTE"
     misc_feature    385645..386550
                     /locus_tag="BCG_0331"
                     /note="Peptidase domain in the S8 and S53 families;
                     Region: Peptidases_S8_S53; cl10459"
                     /db_xref="CDD:271701"
     misc_feature    385648..386796
                     /locus_tag="BCG_0331"
                     /note="type VII secretion-associated serine protease
                     mycosin; Region: T7SS_mycosin; TIGR03921"
                     /db_xref="CDD:234398"
     misc_feature    order(385801..385803,386041..386043,386449..386451)
                     /locus_tag="BCG_0331"
                     /note="active site"
                     /db_xref="CDD:173787"
     misc_feature    order(385801..385803,386449..386451)
                     /locus_tag="BCG_0331"
                     /note="catalytic residues [active]"
                     /db_xref="CDD:173787"
     gene            386808..387803
                     /locus_tag="BCG_0332"
                     /db_xref="GeneID:4698120"
     CDS             386808..387803
                     /locus_tag="BCG_0332"
                     /note="Differs from Rv0292 by 1aa, D217N"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_976430.1"
                     /db_xref="GI:121636207"
                     /db_xref="GeneID:4698120"
                     /translation="MNPIPSWPGRGRVTLVLLAVVPVALAYPWQSTRDYVLLGVAAAV
                     VIGLFGFWRGLYFTTIARRGLAILRRRRRIAEPATCTRTTVLVWVGPPASDTNVLPLT
                     LIARYLDRYGIRADTIRITSRVTASGDCRTWVGLTVVADDNLAALQARSARIPLQETA
                     QVAARRLADHLREIGWEAGTAAPDEIPALVAADSRETWRGMRHTDSDYVAAYRVSADA
                     ELPDTLPAIRSRPAQETWIALEIAYAAGSSTRYTVAAACALRTDWRPGGTAPVAGLLP
                     QHGNHVPALTALDPRSTRRLDGHTDAPADLLTRLHWPTPTAGAHRAPLTNAVSRT"
     misc_feature    386838..387692
                     /locus_tag="BCG_0332"
                     /note="type VII secretion protein EccE; Region: T7SS_EccE;
                     TIGR03923"
                     /db_xref="CDD:234399"
     gene            complement(387790..388992)
                     /locus_tag="BCG_0333c"
                     /db_xref="GeneID:4695810"
     CDS             complement(387790..388992)
                     /locus_tag="BCG_0333c"
                     /note="Differs from Rv0293c and Mb0301c by 1aa, S263G"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_976431.1"
                     /db_xref="GI:121636208"
                     /db_xref="GeneID:4695810"
                     /translation="MSGTFTADAIGPPVPIPDVPGADAGAEGLPSRSVLSARQRILVE
                     SSAIADVALRTAVASVLSATVTPAVVANALRHVNEGSERSNLNFYAELAAAHDPAKSF
                     PAPTELPKVTSRPASPLTEWVARGTVDNIAFASGFRAINPTMRQRWSALTANNIVHAQ
                     HWRHRDGPRPTLCVIHGFMGSSYLLNGLFFSLPWYYRSGYDVLLYTLPFHGQRAEKFS
                     PFSGFGYFTSGLSGFAEAMAQAVYDFRSIVDYLRHIGVDRIALTSISLGGYTSALLAS
                     VESRLEAVIPNCPVVMPAKLFDEWFPANKLVKLGLRLTNISRDELIAGLAYHGPLNYR
                     PLLPKDRRMIITGLGDRMAPPEHAVTLWKQWDRCALHWFPGSHLLHVSQLDYLRRMTV
                     FLQGLMFD"
     misc_feature    complement(387826..388470)
                     /locus_tag="BCG_0333c"
                     /note="Alpha/beta hydrolase family; Region: Abhydrolase_6;
                     pfam12697"
                     /db_xref="CDD:257231"
     misc_feature    complement(387814..>388404)
                     /locus_tag="BCG_0333c"
                     /note="Uncharacterized conserved protein (DUF2048);
                     Region: DUF2048; pfam09752"
                     /db_xref="CDD:255531"
     gene            389099..389884
                     /gene="tam"
                     /locus_tag="BCG_0334"
                     /db_xref="GeneID:4696893"
     CDS             389099..389884
                     /gene="tam"
                     /locus_tag="BCG_0334"
                     /EC_number="2.1.1.-"
                     /note="catalyzes the formation of
                     (E)-3-(methoxycarbonyl)pent-2-enedioate and
                     S-adenosyl-L-homocysteine from S-adenosyl-L-methionine and
                     trans-aconitate"
                     /codon_start=1
                     /transl_table=11
                     /product="trans-aconitate 2-methyltransferase"
                     /protein_id="YP_976432.1"
                     /db_xref="GI:121636209"
                     /db_xref="GeneID:4696893"
                     /translation="MWDPDVYLAFSGHRNRPFYELVSRVGLERARRVVDLGCGPGHLT
                     RYLARRWPGAVIEALDSSPEMVAAAAERGIDATTGDLRDWKPKPDTDVVVSNAALHWV
                     PEHSDLLVRWVDELAPGSWIAVQIPGNFETPSHAAVRALARREPYAKLMRDIPFRVGA
                     VVQSPAYYAELLMDTGCKVDVWETTYLHQLTGEHPVLDWITGSALVPVRERLSDESWQ
                     QFRQELIPLLNDAYPPRADGSTIFPFRRLFMVAEVGGARRSGG"
     misc_feature    389099..389863
                     /gene="tam"
                     /locus_tag="BCG_0334"
                     /note="Trans-aconitate methyltransferase [General function
                     prediction only]; Region: Tam; COG4106"
                     /db_xref="CDD:226591"
     misc_feature    389132..>389248
                     /gene="tam"
                     /locus_tag="BCG_0334"
                     /note="S-adenosylmethionine-dependent methyltransferases
                     (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes
                     that use S-adenosyl-L-methionine (SAM or AdoMet) as a
                     substrate for methyltransfer, creating the product
                     S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases;
                     cl17173"
                     /db_xref="CDD:271798"
     misc_feature    389192..389476
                     /gene="tam"
                     /locus_tag="BCG_0334"
                     /note="S-adenosylmethionine-dependent methyltransferases
                     (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes
                     that use S-adenosyl-L-methionine (SAM or AdoMet) as a
                     substrate for methyltransfer, creating the product
                     S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases;
                     cd02440"
                     /db_xref="CDD:100107"
     misc_feature    order(389204..389224,389276..389281,389333..389341,
                     389384..389386)
                     /gene="tam"
                     /locus_tag="BCG_0334"
                     /note="S-adenosylmethionine binding site [chemical
                     binding]; other site"
                     /db_xref="CDD:100107"
     gene            complement(389873..390676)
                     /locus_tag="BCG_0335c"
                     /db_xref="GeneID:4696339"
     CDS             complement(389873..390676)
                     /locus_tag="BCG_0335c"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_976433.1"
                     /db_xref="GI:121636210"
                     /db_xref="GeneID:4696339"
                     /translation="MSRAVRPYLVLATQRSGSTLLVESLRATGCAGEPQEFFQYLPST
                     GMAPQPREWFAGVDDDTILQLLDPLDPGTPDTATPVAWREHVRTSGRTPNGVWGGKLM
                     WNQTALLQQRAAQLPDRSGDGLRAAIRDVIGNEPVFVHVHRPDVVSQAVSFWRAVQTQ
                     VWRGHPDPKRDSQAVYHAGAIAHIIRNLRDQENGWRAWFAEEGIDPIDIAYPVLWRNL
                     TAIVASVLDAIGQDPKLAPAPMLERQANQRSDEWVDRYRAEAPRLGLPT"
     misc_feature    complement(389876..390676)
                     /locus_tag="BCG_0335c"
                     /note="Uncharacterized protein conserved in bacteria
                     [Function unknown]; Region: COG4424"
                     /db_xref="CDD:226848"
     gene            complement(390686..392083)
                     /locus_tag="BCG_0336c"
                     /db_xref="GeneID:4697957"
     CDS             complement(390686..392083)
                     /locus_tag="BCG_0336c"
                     /EC_number="3.-.-.-"
                     /codon_start=1
                     /transl_table=11
                     /product="sulfatase"
                     /protein_id="YP_976434.1"
                     /db_xref="GI:121636211"
                     /db_xref="GeneID:4697957"
                     /translation="MTSERATGQRENLLIVHWHDLGRYLGVYHHPDVYSPRLDRLAAE
                     GILFTRAHATAPLCTPSRGSLFTGRYPQSNGLVGLAHHGWEYRTGVQTLPQLLSESGW
                     YSALFGMQHETSYPKRLGFDEFDVSNSYCEYVVAKAQDWLHNRVPALDGQRFLLTAGF
                     FETHRPYPHERYRPADSAAVELPDYLPDTPEVRQDVAEFYGSIATADEAVGRLLDTLA
                     DTGLDASTWVVFVTDHGPAFPRAKSTLYDAGTGIALIIRPPTRRAMAPRVYDELFSGV
                     DLVPTLLDLLRLEVPADVEGVSHAPALLAPDTENAAVRDHVYTAKTYHDSFDPIRAIR
                     TKEYSYIENYAPRPLLDLPWDIQESPAGMAVAPLVKAPRPQRELYDLRADPTETNNLL
                     AGDDSTQGVAAIAADLAVRLHDWRQRTADVIPSDFAGSRIAERYTETYLRIHRKTPTG
                     RSAIAADRGIDEHCS"
     misc_feature    complement(390851..392056)
                     /locus_tag="BCG_0336c"
                     /note="Arylsulfatase A and related enzymes [Inorganic ion
                     transport and metabolism]; Region: AslA; COG3119"
                     /db_xref="CDD:225661"
     misc_feature    complement(391226..392050)
                     /locus_tag="BCG_0336c"
                     /note="Sulfatase; Region: Sulfatase; pfam00884"
                     /db_xref="CDD:250201"
     gene            392262..394082
                     /gene="PE_PGRS5"
                     /locus_tag="BCG_0337"
                     /db_xref="GeneID:4697403"
     CDS             392262..394082
                     /gene="PE_PGRS5"
                     /locus_tag="BCG_0337"
                     /note="In Mycobacterium bovis BCG Pasteur, and
                     Mycobacterium bovis, a 45 bp in-frame insertion leads to a
                     longer product compared to its homolog in Mycobacterium
                     tuberculosis strain H37Rv (606 aa versus 591 aa)"
                     /codon_start=1
                     /transl_table=11
                     /product="PE-PGRS family protein"
                     /protein_id="YP_976435.1"
                     /db_xref="GI:121636212"
                     /db_xref="GeneID:4697403"
                     /translation="MSFVIAQPEMIAAAAGELASIRSAINAANAAAAAQTTGVMSAAA
                     DEVSTAVAALFSSHAQAYQAASAQAAAFHAQVVRTLTVDAGAYASAEAANAGPNMLAA
                     VNAPAQALLGRPLIGNGANGAPGTGQAGGDGGLLFGNGGNGGSGAPGQAGGAGGAAGF
                     FGNGGNGGDGGAGANGGAGGTAGWFFGFGGNGGAGGIGVAGINGGLGGAGGDGGNAGF
                     FGNGGNGGMGGAGAAGVNAVNPGLATPVTPAANGGNGLNLVGVPGTAGGGADGANGSA
                     IGQAGGAGGDGGNASTSGGIGIAQTGGAGGAGGAGGDGAPGGNGGNGGSVEHTGATGS
                     SASGGNGATGGNGGVGAPGGAGGNGGHVSGGSVNTAGAGGKGGNGGTGGAGGPGGHGG
                     SVLSGPVGDSGNGGAGGDGGAGVSATDIAGTGGRGGNGGHGGLWIGNGGDGGAGGVGG
                     VGGAGAAGAIGGHGGDGGSVNTPIGGSEAGDGGKGGLGGDGGDGAAGGDGGAGGDGGG
                     RGIFGQFGAGGAGGAGGVGGAGGAGGTGGGGGNGGAIFNAGTPGAAGTGGDGGVGGTG
                     AAGGKGGAGGSGGVNGATGADGAKGLDGATGGKGNNGNPG"
     misc_feature    392262..>392435
                     /gene="PE_PGRS5"
                     /locus_tag="BCG_0337"
                     /note="PE family; Region: PE; pfam00934"
                     /db_xref="CDD:250239"
     gene            394225..394452
                     /locus_tag="BCG_0338"
                     /db_xref="GeneID:4695718"
     CDS             394225..394452
                     /locus_tag="BCG_0338"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_976436.1"
                     /db_xref="GI:121636213"
                     /db_xref="GeneID:4695718"
                     /translation="MTKEKISVTVDAAVLAAIDADARAAGLNRSEMIEQALRNEHLRV
                     ALRDYTAKTVPALDIDAYAQRVYQANRAAGS"
     gene            394449..394751
                     /locus_tag="BCG_0339"
                     /db_xref="GeneID:4698968"
     CDS             394449..394751
                     /locus_tag="BCG_0339"
                     /note="Differs from Mb0307 by 1aa, S13N"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_976437.1"
                     /db_xref="GI:121636214"
                     /db_xref="GeneID:4698968"
                     /translation="MIAPGDIAPRRDSEHELYVAVLSNALHRAADTGRVITCPFIPGR
                     VPEDLLAMVVAVEQPNGTLLPELVQWLHVAALGAPLGNAGVAALREAASVVTALLC"
     gene            394799..395020
                     /locus_tag="BCG_0340"
                     /db_xref="GeneID:4698642"
     CDS             394799..395020
                     /locus_tag="BCG_0340"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_976438.1"
                     /db_xref="GI:121636215"
                     /db_xref="GeneID:4698642"
                     /translation="MSDVLIRDIPDDVLASLDAIAARLGLSRTEYIRRRLAQDAQTAR
                     VTVTAADLRRLRGAVAGLGDPELMRQAWR"
     misc_feature    394823..>394900
                     /locus_tag="BCG_0340"
                     /note="hypothetical protein; Region: PHA01748"
                     /db_xref="CDD:222832"
     gene            395017..395442
                     /locus_tag="BCG_0341"
                     /db_xref="GeneID:4698422"
     CDS             395017..395442
                     /locus_tag="BCG_0341"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_976439.1"
                     /db_xref="GI:121636216"
                     /db_xref="GeneID:4698422"
                     /translation="MTDQRWLIDKSALVRLTDSPDMEIWSNRIERGLVHITGVTRLEV
                     GFSAECGEIARREFREPPLSAMPVEYLTPRIEDRALEVQTLLADRGHHRGPSIPDLLI
                     AATAELSGLTVLHVDKDFDAIAALTGQKTERLTHRPPSA"
     misc_feature    395035..395415
                     /locus_tag="BCG_0341"
                     /note="PIN domain of the Rv0301 toxin of Mycobacterium
                     tuberculosis and other uncharacterized, annotated PilT
                     protein domain proteins; Region: PIN_MtRv0301; cd09882"
                     /db_xref="CDD:189052"
     misc_feature    order(395041..395043,395143..395145,395311..395313,
                     395365..395367)
                     /locus_tag="BCG_0341"
                     /note="putative active site [active]"
                     /db_xref="CDD:189052"
     gene            395579..396211
                     /locus_tag="BCG_0342"
                     /db_xref="GeneID:4695467"
     CDS             395579..396211
                     /locus_tag="BCG_0342"
                     /note="Differs from Mb0310 by 1aa A124V"
                     /codon_start=1
                     /transl_table=11
                     /product="TetR family transcriptional regulator"
                     /protein_id="YP_976440.1"
                     /db_xref="GI:121636217"
                     /db_xref="GeneID:4695467"
                     /translation="MGVPAKKKQQQGERSRESILDATERLMATKGYAATSISDIRDAC
                     GLAPSSIYWHFGSKEGVLAAMMERGAQRFFAAIPTWDEAHGPVEQRSERQLTELVSLQ
                     SQHPDFLRLFYLLSMERSQDPAVAAVVRRVRNTAIARFRDSITHLLPSDIPPGKADLV
                     VAELTAFAVALSDGVYFAGHLEPDTTDVERMYRRLRQALEALIPVLLEET"
     misc_feature    395588..396190
                     /locus_tag="BCG_0342"
                     /note="Transcriptional regulator [Transcription]; Region:
                     AcrR; COG1309"
                     /db_xref="CDD:224228"
     misc_feature    395633..395773
                     /locus_tag="BCG_0342"
                     /note="Bacterial regulatory proteins, tetR family; Region:
                     TetR_N; pfam00440"
                     /db_xref="CDD:249860"
     misc_feature    <395990..396190
                     /locus_tag="BCG_0342"
                     /note="Bacterial transcriptional repressor; Region:
                     TetR_C_6; pfam13977"
                     /db_xref="CDD:258229"
     gene            396208..397116
                     /locus_tag="BCG_0343"
                     /db_xref="GeneID:4697256"
     CDS             396208..397116
                     /locus_tag="BCG_0343"
                     /EC_number="1.-.-.-"
                     /codon_start=1
                     /transl_table=11
                     /product="dehydrogenase/reductase"
                     /protein_id="YP_976441.1"
                     /db_xref="GI:121636218"
                     /db_xref="GeneID:4697256"
                     /translation="MNTGTAVITGASSGLGLQCARALLRRDASWHVVLAVRDPARGRA
                     AMEELGEPNRCSVLEVDLASVRSVRSFVETVRTTPLPPIRALVCNAGLQVVSGIAFTD
                     DGVEMTFGVNHLGHFALVTGILDWLARPARIVVVSSGTHDPSKHTGMPDPRYTCAADL
                     AHPPTDQNTPAEGRRRYTTSKLCNVLFTYELDRRLDHGEQGVMVNAFDPGLMPGSGLA
                     RDYPPILRLAYRLLSPMLRVLPFVHSTRVSGEHLAALAVDPRFAGVTGQYFAGAKAIR
                     SSAESYDRAKALDLWETSERLLAQVT"
     misc_feature    396214..397107
                     /locus_tag="BCG_0343"
                     /note="light-dependent protochlorophyllide reductase
                     (LPOR)-like, classical (c)-like SDRs; Region:
                     LPOR_like_SDR_c_like; cd09810"
                     /db_xref="CDD:187670"
     misc_feature    396220..397098
                     /locus_tag="BCG_0343"
                     /note="short chain dehydrogenase; Provisional; Region:
                     PRK06197"
                     /db_xref="CDD:235737"
     misc_feature    order(396235..396237,396241..396252,396313..396321,
                     396385..396393,396472..396480,396538..396540,
                     396631..396639,396736..396738,396748..396750,
                     396832..396843,396847..396852)
                     /locus_tag="BCG_0343"
                     /note="putative NAD(P) binding site [chemical binding];
                     other site"
                     /db_xref="CDD:187670"
     misc_feature    order(396541..396543,396637..396639,396736..396738,
                     396748..396750)
                     /locus_tag="BCG_0343"
                     /note="active site"
                     /db_xref="CDD:187670"
     gene            complement(397124..400567)
                     /gene="PPE5"
                     /locus_tag="BCG_0344c"
                     /db_xref="GeneID:4697219"
     CDS             complement(397124..400567)
                     /gene="PPE5"
                     /locus_tag="BCG_0344c"
                     /note="In Mycobacterium tuberculosis strain H37Rv, PPE5
                     and PPE6 exist as separate genes. In Mycobacterium bovis
                     BCG Pasteur, and Mycobacterium bovis, a frameshift due to
                     a single base deletion (g-*) leads to a shorter CDS
                     (Mb0312c and BCG_0344c) equivalent to the 3' end of
                     Rv0304c/PPE5. Differs from Rv0304c by 3aa, S481G, F708S,
                     A955T, and 5 codon in-frame deletion at position 503"
                     /codon_start=1
                     /transl_table=11
                     /product="PPE family protein"
                     /protein_id="YP_976442.1"
                     /db_xref="GI:121636219"
                     /db_xref="GeneID:4697219"
                     /translation="MFNSGDGNIGFFNSGTGNFGIGNTGTGNFGIGNSGSTSTGLFNS
                     GDGNTGGFNPGNFNTGNFNTGSFNTGGFNAGNTNTGHFNTGNYNTGIANTGDVSTGAF
                     ISGNYSNGILWRGDYQGLIGYSYALTIPEIPAHLDVNIPIDIPITGSFTDLVVDNFTI
                     PIIGFESFAFSFHIHTEPDIGPIIVPSFVLSVPTFAIAVGGPTTAINISATAGLGPIT
                     IPIIDIPAAPGIGNSTTSPSSGFFNTGAGTASGFGNVGGNTSGLWNLASAASGVSGLL
                     NVGALGSGVANVGNTISGIYNTSPLDLGTPAFGSGLANIAGLLQGGAGTTILDLAGLG
                     NLNVGLANLGGSNFGIGNTGIFNVGFANVGNHNIGLANLGNYSVGFANSGNYHIGIAN
                     TGSANIGFANTGSGNIGIGLTGTGQIGFGSFNSGSHNIGLFNSGDGNVGFFNSGTGNV
                     GIGNTGTANFGIANSGSFNTGLGNTGSTNTSLFNPGNVNTGVGNTGSINTGSFNTGST
                     NTGSFNLGDHNTGSFNSGDYNTGYFNAGDYNTGVANTGNVNTGAFISGNYSNGFFWRG
                     DYQGLIGLSTTITIPEIPYRYDLSVPIDIPITGTVVATTPNSFTIPGFQIRVLLGPAA
                     VLVNEMIGPITIDVNQVIAIDSPIQQTISMVGTGGFGPIPIGISIGGTPGFGNSTTGP
                     SSGFFHTGAGHVSGFGNFGAGNMSGFGNFGAGNSGFFNAGGLGNSGLLNFGALQSGLA
                     NLGNTISGVYNTSTLDLATPAFGSGIANIGANLAGLFLDNTGNLTLNFGVANQGGLNA
                     GIGNLGSVNIGFVNTGDSNLGIGNLGDLNFGGVNIGGNNIGIANTGIFDIGLANLGSY
                     NIGLANLGDDNLGFGNAGSYNIGFANFGSDNLGFANTGSYNIGFANTGNNNIGVGLTG
                     NGQIGIGSLNSGSNNIGLFNSGSGNIGFFNSGTGNVGIFNAGTGNFGLANSGGFNTGI
                     GNAGSTNTGVFNPGDLNTGSFNPGSFNTGGFNPGSGNTGYLNTGDYNTGVANTGDVDT
                     GAFITGSYSNGFLVSGDYQGLIGLPLLGIPVTPGYFNLTGGPSSGFFNSGAGSVSGFV
                     NSGAGLSGYLNTGALGSGVANVGNTISGWLNASALDLATPGFLSGIGNFGTNLAGFFR
                     G"
     misc_feature    complement(400460..400564)
                     /gene="PPE5"
                     /locus_tag="BCG_0344c"
                     /note="Pentapeptide repeats (8 copies); Region:
                     Pentapeptide_2; pfam01469"
                     /db_xref="CDD:250641"
     misc_feature    complement(400370..400489)
                     /gene="PPE5"
                     /locus_tag="BCG_0344c"
                     /note="Pentapeptide repeats (8 copies); Region:
                     Pentapeptide_2; pfam01469"
                     /db_xref="CDD:250641"
     misc_feature    complement(400280..400396)
                     /gene="PPE5"
                     /locus_tag="BCG_0344c"
                     /note="Pentapeptide repeats (8 copies); Region:
                     Pentapeptide_2; pfam01469"
                     /db_xref="CDD:250641"
     misc_feature    complement(398867..>399811)
                     /gene="PPE5"
                     /locus_tag="BCG_0344c"
                     /note="PPE-repeat proteins [Cell motility and secretion];
                     Region: COG5651"
                     /db_xref="CDD:227938"
     misc_feature    complement(399200..399310)
                     /gene="PPE5"
                     /locus_tag="BCG_0344c"
                     /note="Pentapeptide repeats (8 copies); Region:
                     Pentapeptide_2; pfam01469"
                     /db_xref="CDD:250641"
     misc_feature    complement(399047..399163)
                     /gene="PPE5"
                     /locus_tag="BCG_0344c"
                     /note="Pentapeptide repeats (8 copies); Region:
                     Pentapeptide_2; pfam01469"
                     /db_xref="CDD:250641"
     misc_feature    complement(398957..399073)
                     /gene="PPE5"
                     /locus_tag="BCG_0344c"
                     /note="Pentapeptide repeats (8 copies); Region:
                     Pentapeptide_2; pfam01469"
                     /db_xref="CDD:250641"
     misc_feature    complement(398897..399013)
                     /gene="PPE5"
                     /locus_tag="BCG_0344c"
                     /note="Pentapeptide repeats (8 copies); Region:
                     Pentapeptide_2; pfam01469"
                     /db_xref="CDD:250641"
     misc_feature    complement(397427..>398254)
                     /gene="PPE5"
                     /locus_tag="BCG_0344c"
                     /note="PPE-repeat proteins [Cell motility and secretion];
                     Region: COG5651"
                     /db_xref="CDD:227938"
     misc_feature    complement(398078..398197)
                     /gene="PPE5"
                     /locus_tag="BCG_0344c"
                     /note="Pentapeptide repeats (8 copies); Region:
                     Pentapeptide_2; pfam01469"
                     /db_xref="CDD:250641"
     misc_feature    complement(397928..398047)
                     /gene="PPE5"
                     /locus_tag="BCG_0344c"
                     /note="Pentapeptide repeats (8 copies); Region:
                     Pentapeptide_2; pfam01469"
                     /db_xref="CDD:250641"
     misc_feature    complement(397841..397957)
                     /gene="PPE5"
                     /locus_tag="BCG_0344c"
                     /note="Pentapeptide repeats (8 copies); Region:
                     Pentapeptide_2; pfam01469"
                     /db_xref="CDD:250641"
     misc_feature    complement(397667..397783)
                     /gene="PPE5"
                     /locus_tag="BCG_0344c"
                     /note="Pentapeptide repeats (8 copies); Region:
                     Pentapeptide_2; pfam01469"
                     /db_xref="CDD:250641"
     misc_feature    complement(397547..397663)
                     /gene="PPE5"
                     /locus_tag="BCG_0344c"
                     /note="Pentapeptide repeats (8 copies); Region:
                     Pentapeptide_2; pfam01469"
                     /db_xref="CDD:250641"
     misc_feature    complement(397487..397603)
                     /gene="PPE5"
                     /locus_tag="BCG_0344c"
                     /note="Pentapeptide repeats (8 copies); Region:
                     Pentapeptide_2; pfam01469"
                     /db_xref="CDD:250641"
     gene            complement(400711..406638)
                     /gene="PPE6"
                     /locus_tag="BCG_0345c"
                     /db_xref="GeneID:4696876"
     CDS             complement(400711..406638)
                     /gene="PPE6"
                     /locus_tag="BCG_0345c"
                     /note="In Mycobacterium tuberculosis strain H37Rv, PPE5
                     and PPE6 exist as separate genes. In Mycobacterium bovis
                     BCG Pasteur, and Mycobacterium bovis, a single base
                     deletion (t-*) resulting in the absence of a stop codon
                     leads to a longer product. The second part of this CDS
                     shares homology with the 5' end of Rv0304c/PPE5. Differs
                     from Mb0313c by in-frame deletion of 10 codons"
                     /codon_start=1
                     /transl_table=11
                     /product="PPE family protein"
                     /protein_id="YP_976443.1"
                     /db_xref="GI:121636220"
                     /db_xref="GeneID:4696876"
                     /translation="MDFVVSAPEVNSLRMYLGAGSGPMLAAAAAWDGLADELAVAASW
                     FGSVTSGLADAAWRGPAAVAMARAVAPYLGWLISATAQAEQAAAQARVAVATFEAARA
                     ATVHPAIVAANRAVLVSLVSSNLLGFNAPAIAATEAAYERMWAQDVAAMVGYHAGASA
                     AVSALMPFTQQLKKLAGLSERLTSAAAAAAGPPSAAGFNLGLANVGANNVGNGNVGVF
                     NVGFGNLGSYNLGFANLGSDNLGLANLGGHNIGFANTGSNNVGFGNTGSNNVGIGLTG
                     NGQIGFGSFNSGSHNIGLFNSGSGNVGLFNSGTGNFGIGNSGTGNFGLGNTGSTNTGW
                     FNTGDVNTGNFNTGNYNTGSFNAGNYNTGYFNTGDYNTGVANTGNVNTGAFIAGNYSN
                     GVLWRGDYQGLIGADIALEIPAIPINAQLFSMPIHQVMVMPGSVMTIPGMRLPFTSIV
                     PFVVYYGPVELPQSTLTLPTVTITVGGPTTTIDGNLTGMVGGVSIPLIKIPAAPGFGN
                     STTSPSSGFFNAGAGTASGFGNFGGGASGFWNLASATSGLSGFGNVGALGSGVANVGN
                     TISGLYNTSTSNLATPAFNSGLLHHSVGTMTLNFGLANVGGNNVGGANAGIFNVGLAN
                     LGDYNIGFGNLGGDNLGFAHAGSYNIGFANTGSNNLGFANTGDNNIGFANIGSNNIGI
                     GLTGSGQIGFGSLNSGSHNIGLFNSGDGNIGLFNSGSGNFGIGNAGTGNWGIGNSGAG
                     NFGIGNAGSTNTGLFNSGDLNTGSLNPGSYNTGSVNTGSVNTGGFNAGNYNTGYFNTG
                     DYNTGMANTGNINTGAFISGNHSNGLLWRGDNQGLIDLAIGVDIPEIPIVSVDVNIPI
                     HIPITASFTDIVYSGLDLPPNTAVTVIFFGPVDIDPFTVPVIRITGPTPVVMVGGPTT
                     AINIGATVGVDAINIPIIHIPATPGFGNSTGGLSSGFFNSGAGSASGFGNFGGAASGF
                     MNLVSTTSGMSGFLNVGALGSGVANVGNTISGIYNVGTSDLSTPAVNSGLANIGTNIA
                     GLLRDGAGTAAINLGLANHGNLNVGFASLGGFNFGGATIGHNNVGIGNTGIFDVGLAN
                     LGSYNIGFGNLGDDNLGFGNFGSYNIGFGNVGNDNLGFANAGGGNIGFANTGSNNVGF
                     GNTGSNNVGIGLTGNGQIGFGSFNSGSGNIGLFNSGSNNIGFFNSGSGNFGIANSGSF
                     NTGIGNTGNTNTGLFNSGDVNTGAFNPGSFNTGSFNTGSFNTGGFNPGNTNTGYLNIG
                     NYNTGIANTGDVDTGAFITGNYSNGLFLSGDYQGLVGLNLVIDMPLPISLGVNIPIDI
                     PITASAGNITLMGVTIPPTGDIVLSSIAGQRAHFGPITIPNITVVGPTTTVAIGGPNT
                     AITITGGGAIRIPLISIPAAPGFGNSTTNPSSGFFNTGAGGASGFGNFGGANSGFWNL
                     ASATSGASGLLNVGALGSGLANVGTTVSGFYNTSTSDLATPAFNSGLANISTSIAGLL
                     RDSTGTMVLNLGLANHGTLNVGIANLGDYNIGFANLGSANFGSANIGGNNIGGANTGI
                     FDIGLANLGSYNIGFGNFGDDNLGFGNLGSYNVGFGNLGNDNLGFANTGSNNIGFANT
                     GSNNIGIGLTGDGQIGFGSLNSGSGNIGLFNSGSGNIGFFNSGNGNVGIGNTGTANFG
                     LGNTGSTNTGFFNSGDVNTGIGNTGSFNTGSFNPGDSNTGDFNPGSYNTGLGNTGDVD
                     TGAFISGSYSNGFLWSGNYQGLIGLHAALAIPEIALTFGVDIPIHIPINIDAGVVTLQ
                     GFSIVAAENNIDFTPIIIPTINITLPTAAITVGGPTTSIGITASAGIGSITIPIIDIP
                     ATSGFGNSTTSPSSGFFNSGAGSASGFLNVVAGASGISGYLNVGALGSGVTNVGHTVS
                     GFYNASALDLVTPAFASGLMRDGMGTMTLNLGLANLGSNNAGFGNTGIFDVGVANLGN
                     YNIGFGNFGDDNLALPT"
     misc_feature    complement(405442..406638)
                     /gene="PPE6"
                     /locus_tag="BCG_0345c"
                     /note="PPE-repeat proteins [Cell motility and secretion];
                     Region: COG5651"
                     /db_xref="CDD:227938"
     misc_feature    complement(406150..406617)
                     /gene="PPE6"
                     /locus_tag="BCG_0345c"
                     /note="PPE family; Region: PPE; pfam00823"
                     /db_xref="CDD:250158"
     misc_feature    complement(405826..405942)
                     /gene="PPE6"
                     /locus_tag="BCG_0345c"
                     /note="Pentapeptide repeats (8 copies); Region:
                     Pentapeptide_2; pfam01469"
                     /db_xref="CDD:250641"
     misc_feature    complement(405652..405768)
                     /gene="PPE6"
                     /locus_tag="BCG_0345c"
                     /note="Pentapeptide repeats (8 copies); Region:
                     Pentapeptide_2; pfam01469"
                     /db_xref="CDD:250641"
     misc_feature    complement(405562..405681)
                     /gene="PPE6"
                     /locus_tag="BCG_0345c"
                     /note="Pentapeptide repeats (8 copies); Region:
                     Pentapeptide_2; pfam01469"
                     /db_xref="CDD:250641"
     misc_feature    complement(405502..405618)
                     /gene="PPE6"
                     /locus_tag="BCG_0345c"
                     /note="Pentapeptide repeats (8 copies); Region:
                     Pentapeptide_2; pfam01469"
                     /db_xref="CDD:250641"
     misc_feature    complement(404152..>405159)
                     /gene="PPE6"
                     /locus_tag="BCG_0345c"
                     /note="PPE-repeat proteins [Cell motility and secretion];
                     Region: COG5651"
                     /db_xref="CDD:227938"
     misc_feature    complement(404596..404712)
                     /gene="PPE6"
                     /locus_tag="BCG_0345c"
                     /note="Pentapeptide repeats (8 copies); Region:
                     Pentapeptide_2; pfam01469"
                     /db_xref="CDD:250641"
     misc_feature    complement(404425..404538)
                     /gene="PPE6"
                     /locus_tag="BCG_0345c"
                     /note="Pentapeptide repeats (8 copies); Region:
                     Pentapeptide_2; pfam01469"
                     /db_xref="CDD:250641"
     misc_feature    complement(404302..404421)
                     /gene="PPE6"
                     /locus_tag="BCG_0345c"
                     /note="Pentapeptide repeats (8 copies); Region:
                     Pentapeptide_2; pfam01469"
                     /db_xref="CDD:250641"
     misc_feature    complement(404242..404358)
                     /gene="PPE6"
                     /locus_tag="BCG_0345c"
                     /note="Pentapeptide repeats (8 copies); Region:
                     Pentapeptide_2; pfam01469"
                     /db_xref="CDD:250641"
     misc_feature    complement(404182..404298)
                     /gene="PPE6"
                     /locus_tag="BCG_0345c"
                     /note="Pentapeptide repeats (8 copies); Region:
                     Pentapeptide_2; pfam01469"
                     /db_xref="CDD:250641"
     misc_feature    complement(402760..>403785)
                     /gene="PPE6"
                     /locus_tag="BCG_0345c"
                     /note="PPE-repeat proteins [Cell motility and secretion];
                     Region: COG5651"
                     /db_xref="CDD:227938"
     misc_feature    complement(403291..403410)
                     /gene="PPE6"
                     /locus_tag="BCG_0345c"
                     /note="Pentapeptide repeats (8 copies); Region:
                     Pentapeptide_2; pfam01469"
                     /db_xref="CDD:250641"
     misc_feature    complement(403174..403290)
                     /gene="PPE6"
                     /locus_tag="BCG_0345c"
                     /note="Pentapeptide repeats (8 copies); Region:
                     Pentapeptide_2; pfam01469"
                     /db_xref="CDD:250641"
     misc_feature    complement(403000..403119)
                     /gene="PPE6"
                     /locus_tag="BCG_0345c"
                     /note="Pentapeptide repeats (8 copies); Region:
                     Pentapeptide_2; pfam01469"
                     /db_xref="CDD:250641"
     misc_feature    complement(402910..403026)
                     /gene="PPE6"
                     /locus_tag="BCG_0345c"
                     /note="Pentapeptide repeats (8 copies); Region:
                     Pentapeptide_2; pfam01469"
                     /db_xref="CDD:250641"
     misc_feature    complement(402820..402936)
                     /gene="PPE6"
                     /locus_tag="BCG_0345c"
                     /note="Pentapeptide repeats (8 copies); Region:
                     Pentapeptide_2; pfam01469"
                     /db_xref="CDD:250641"
     misc_feature    complement(<402208..402678)
                     /gene="PPE6"
                     /locus_tag="BCG_0345c"
                     /note="BDLF3; Provisional; Region: PHA03255"
                     /db_xref="CDD:165513"
     misc_feature    complement(401407..>402402)
                     /gene="PPE6"
                     /locus_tag="BCG_0345c"
                     /note="PPE-repeat proteins [Cell motility and secretion];
                     Region: COG5651"
                     /db_xref="CDD:227938"
     misc_feature    complement(401998..402117)
                     /gene="PPE6"
                     /locus_tag="BCG_0345c"
                     /note="Pentapeptide repeats (8 copies); Region:
                     Pentapeptide_2; pfam01469"
                     /db_xref="CDD:250641"
     misc_feature    complement(401818..401937)
                     /gene="PPE6"
                     /locus_tag="BCG_0345c"
                     /note="Pentapeptide repeats (8 copies); Region:
                     Pentapeptide_2; pfam01469"
                     /db_xref="CDD:250641"
     misc_feature    complement(401617..401736)
                     /gene="PPE6"
                     /locus_tag="BCG_0345c"
                     /note="Pentapeptide repeats (8 copies); Region:
                     Pentapeptide_2; pfam01469"
                     /db_xref="CDD:250641"
     misc_feature    complement(401527..401646)
                     /gene="PPE6"
                     /locus_tag="BCG_0345c"
                     /note="Pentapeptide repeats (8 copies); Region:
                     Pentapeptide_2; pfam01469"
                     /db_xref="CDD:250641"
     misc_feature    complement(401467..401583)
                     /gene="PPE6"
                     /locus_tag="BCG_0345c"
                     /note="Pentapeptide repeats (8 copies); Region:
                     Pentapeptide_2; pfam01469"
                     /db_xref="CDD:250641"
     gene            406841..407512
                     /locus_tag="BCG_0346"
                     /db_xref="GeneID:4698215"
     CDS             406841..407512
                     /locus_tag="BCG_0346"
                     /EC_number="1.-.-.-"
                     /codon_start=1
                     /transl_table=11
                     /product="oxidoreductase"
                     /protein_id="YP_976444.1"
                     /db_xref="GI:121636221"
                     /db_xref="GeneID:4698215"
                     /translation="MFSAPERRAVYRVIAERRDMRRFVPGGVVSEDVLARLLHAAHAA
                     PSVGLMQPWRFIRITDETLKRRIHALVDDERLLTAEALGAREEEFLALKVEGILDCAE
                     LLVVALCDRRGSYIFGRRTLPQMDLASVSCAIQNLWLAARSEGLGMGWVSLFDPQRLA
                     ALLAMPADAEPVAILCLGPVPEFPDRPALELDGWAYARPLAEFVSENRWSYPSALATD
                     HHHGE"
     misc_feature    406871..407452
                     /locus_tag="BCG_0346"
                     /note="Proteins of this family catalyze the reduction of
                     flavin or nitrocompounds using NAD(P)H as electron donor
                     in a obligatory two-electron transfer,  utilizing FMN or
                     FAD as cofactor. They are often found to be homodimers.
                     Enzymes of this family are...; Region:
                     Nitro_FMN_reductase; cl00514"
                     /db_xref="CDD:260471"
     misc_feature    order(406889..406891,406895..406897,406901..406903,
                     406982..406984,407294..407299)
                     /locus_tag="BCG_0346"
                     /note="FMN binding site [chemical binding]; other site"
                     /db_xref="CDD:239015"
     misc_feature    order(407228..407230,407234..407239,407246..407251,
                     407258..407260)
                     /locus_tag="BCG_0346"
                     /note="dimer interface [polypeptide binding]; other site"
                     /db_xref="CDD:239015"
     gene            complement(407500..407982)
                     /locus_tag="BCG_0347c"
                     /db_xref="GeneID:4695774"
     CDS             complement(407500..407982)
                     /locus_tag="BCG_0347c"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_976445.1"
                     /db_xref="GI:121636222"
                     /db_xref="GeneID:4695774"
                     /translation="MAVIVRKWFGLGRLPADLRCQVEAEGLIYLAEYVAVTRRFTGVI
                     PGLRASHSIASYVGALAFTEQRVLGTLSMVPKLAGRVVDARWDGPQAGAATAEISPTG
                     LQLDLDVADVDPKFSGQLALHFKATIGEDVLSRLPRRSLAFDVPAEYVNLAVGVTYSP
                     "
     gene            408040..408756
                     /locus_tag="BCG_0348"
                     /db_xref="GeneID:4697716"
     CDS             408040..408756
                     /locus_tag="BCG_0348"
                     /codon_start=1
                     /transl_table=11
                     /product="integral membrane protein"
                     /protein_id="YP_976446.1"
                     /db_xref="GI:121636223"
                     /db_xref="GeneID:4697716"
                     /translation="MTRPQALLAVSLAFVATAVYAVMWVGHSQDWGWLHSFDWSLLNA
                     AHDIGIKNPAWVRFWDGVSLILGPVVLRPLGLLAAMVALAKRKIRIALLLLACLPLNA
                     IMTIAAKSVAHRPRPATALVSAHSTSFPSGHALEATASVLALLTVLLPMLHSRFTRHI
                     AITVGALCVLTVGVARVALNVHHPTDVVAGWALGYLYFLVCLCVFRPPSIFGAQRASH
                     ALSPPVEVSRQPEPEVDTAR"
     misc_feature    408058..408672
                     /locus_tag="BCG_0348"
                     /note="Membrane-associated phospholipid phosphatase [Lipid
                     metabolism]; Region: PgpB; COG0671"
                     /db_xref="CDD:223743"
     misc_feature    408130..408657
                     /locus_tag="BCG_0348"
                     /note="PAP2_like_2 proteins. PAP2 is a super-family of
                     phosphatases and haloperoxidases. This subgroup, which is
                     specific to bacteria, lacks functional characterization
                     and may act as a membrane-associated lipid phosphatase;
                     Region: PAP2_like_2; cd03392"
                     /db_xref="CDD:239486"
     misc_feature    order(408364..408366,408385..408387,408430..408438,
                     408565..408567,408583..408585,408595..408597)
                     /locus_tag="BCG_0348"
                     /note="active site"
                     /db_xref="CDD:239486"
     gene            408858..409514
                     /locus_tag="BCG_0349"
                     /db_xref="GeneID:4698232"
     CDS             408858..409514
                     /locus_tag="BCG_0349"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_976447.1"
                     /db_xref="GI:121636224"
                     /db_xref="GeneID:4698232"
                     /translation="MSRLLALLCAAVCTGCVAVVLAPVSLAVVNPWFANSVGNATQVV
                     SVVGTGGSTAKMDVYQRTAAGWQPLKTGITTHIGSAGMAPEAKSGYPATPMGVYSLDS
                     AFGTAPNPGGGLPYTQVGPNHWWSGDDNSPTFNSMQVCQKSQCPFSTADSENLQIPQY
                     KHSVVMGVNKAKVPGKGSAFFFHTTDGGPTAGCVAIDDATLVQIIRWLRPGAVIAIAK
                     "
     misc_feature    408858..409511
                     /locus_tag="BCG_0349"
                     /note="Uncharacterized protein conserved in bacteria
                     [Function unknown]; Region: COG3786"
                     /db_xref="CDD:226309"
     gene            complement(409584..410075)
                     /locus_tag="BCG_0350c"
                     /db_xref="GeneID:4695402"
     CDS             complement(409584..410075)
                     /locus_tag="BCG_0350c"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_976448.1"
                     /db_xref="GI:121636225"
                     /db_xref="GeneID:4695402"
                     /translation="MCCNGVVTPGDPADIAAIKQLKYRYLRALDTKHWDDFTDTLAED
                     VTGDYGSSVGTELHFTNRADLVDYLRQALGPGVITEHRVTHPEITVTGDTATGIWYLQ
                     DRVIVAEFNFMLIGAAFYHDQYRRTTDGWRISATGYDRTYEATMSLAGLNFNIRPGRA
                     LAD"
     misc_feature    complement(409674..410039)
                     /locus_tag="BCG_0350c"
                     /note="SnoaL-like domain; Region: SnoaL_4; pfam13577"
                     /db_xref="CDD:257893"
     gene            410099..411328
                     /locus_tag="BCG_0351"
                     /db_xref="GeneID:4698435"
     CDS             410099..411328
                     /locus_tag="BCG_0351"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_976449.1"
                     /db_xref="GI:121636226"
                     /db_xref="GeneID:4698435"
                     /translation="MSQSRYAGLSRSELAVLLPELLLIGQLIDRSGMAWCIQAFGRQE
                     MLQIAIEEWAGASPIYTKRMQKALNFEGDDVPTIFKGLQLDIGAPPQFMDFRFTLHDR
                     WHGEFHLDHCGALLDVEPMGDDYVVGMCHTIEDPTFDATAIATNPRAQVRPIHRPPRK
                     PADRHPHCAWTVIIDESYPEAEGIPALDAVRETKAATWELDNVDASDDGLVDYSGPLV
                     SDLDFGAFSHSALVRMADEVCLQMHLLNLSFAIAVRKRAKADAQLAISVNTRQLIGVA
                     GLGAERIHRAMALPGGIEGALGVLELHPLLNPAGYVLAETSPDRLVVHNSPAHADGAW
                     ISLCTPASVQPLQAIATAVDPHLKVRISGTDTDWTAELIEADAPASELPEVLVAKVSR
                     GSVFQFEPRRSLPLTVK"
     gene            411483..413345
                     /locus_tag="BCG_0352"
                     /db_xref="GeneID:4698919"
     CDS             411483..413345
                     /locus_tag="BCG_0352"
                     /note="Differs from Rv0312 by 2aa, G159S, L563P"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_976450.1"
                     /db_xref="GI:121636227"
                     /db_xref="GeneID:4698919"
                     /translation="MYDPLGLSIGTTNLVAAGNGGPPVTRRAVLTLYPHCAPKIGVPS
                     QNPNLIEPGALMSGFVERIGDAVALVSPDGSVHDPDLLLVEALDAMVLTAGADASSSE
                     IAIAVPAHWKPGAVHALRNGLRTHVGFVRSGMAPRLVSDAIAALTAVNSELGLPHGGV
                     VGLLDFGGSATYVTLVETKSDSRTSDFQPVSATARYQDFSGSQIDQALLLRVIDQFGY
                     GDDVDPASTAAVGQLGQLREQCRAAKERLSTDVATELFAELAGCSSSIEMTREQLEDL
                     IQDPLTGFIYAFDDMLARHNASWADLAAVVTVGGGANIPLVTQRLSFHTRRPVLTASQ
                     PGCAAAMGALLLANRGGERDSRTRTSIGLATAAAAGTSVIELPAGDVMVIDHEALTDR
                     ELAWSQTDFPSEAPARFEGDSYNEGGPCWSMRLNAVEPPKGPAWRRIRVSQLLIGVSA
                     VVAMTAIGGVALTLTAIERRPSPLPTPIVPGLAPMPPGSVVPSSRAPTPPPPPSTVAP
                     LPSAAPAPTTVAPAPPPPTQVVTTTTAPPVTTTPRPSPTTTTTTAPPSTTTTTELPVT
                     TTSTIPTIPTTTTTVKMTTEWLHVPFLPVPIPVPIPQNPGAGEPQNPFGSLGSG"
     misc_feature    411492..>412493
                     /locus_tag="BCG_0352"
                     /note="Molecular chaperone [Posttranslational
                     modification, protein turnover, chaperones]; Region: DnaK;
                     COG0443"
                     /db_xref="CDD:223520"
     misc_feature    <411786..412487
                     /locus_tag="BCG_0352"
                     /note="Nucleotide-Binding Domain of the sugar
                     kinase/HSP70/actin superfamily; Region:
                     NBD_sugar-kinase_HSP70_actin; cl17037"
                     /db_xref="CDD:271791"
     misc_feature    order(411903..411905,411975..411986,412407..412409)
                     /locus_tag="BCG_0352"
                     /note="nucleotide binding site [chemical binding]; other
                     site"
                     /db_xref="CDD:212657"
     gene            413417..413803
                     /locus_tag="BCG_0353"
                     /db_xref="GeneID:4697371"
     CDS             413417..413803
                     /locus_tag="BCG_0353"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_976451.1"
                     /db_xref="GI:121636228"
                     /db_xref="GeneID:4697371"
                     /translation="MGDYGPFGFDPDEFDRVIREGSEGLRDAFERIGRFLSSSGAGTG
                     WSAIFEDLSRRSRPAPETAGEAGDGVWAIYTVDADGGARVEQVYATELDALRANKDNT
                     DPKRKVRFLPYGIAVSVLDDPVDEAQ"
     misc_feature    <413453..>413797
                     /locus_tag="BCG_0353"
                     /note="Molecular chaperone, HSP90 family
                     [Posttranslational modification, protein turnover,
                     chaperones]; Region: HtpG; COG0326"
                     /db_xref="CDD:223403"
     gene            complement(413806..414468)
                     /locus_tag="BCG_0354c"
                     /db_xref="GeneID:4697400"
     CDS             complement(413806..414468)
                     /locus_tag="BCG_0354c"
                     /note="Differs from Rv0314c by 1aa, A184V"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_976452.1"
                     /db_xref="GI:121636229"
                     /db_xref="GeneID:4697400"
                     /translation="MIVVWEHLCMNPEDDPEARIRELERPLADVARASELGGSQSGGY
                     TYPPGPPPPPYSYGGPFGGPSPRSSSGNRAWWILAAVVVVGVLVLVGGIAAFSAQRLS
                     QGNFVVLSPTPSVSRAVPTPTAQPATTLPPAGASLSVSGVNVNRTIACNDSIVSVSGM
                     SNTVVITGHCTSLTVSGMRNSVTADSVDTIEAAGFNNEVTYHSGSPKISNAGGSNSVQ
                     QG"
     misc_feature    complement(413821..414003)
                     /locus_tag="BCG_0354c"
                     /note="Protein of unknown function (DUF3060); Region:
                     DUF3060; pfam11259"
                     /db_xref="CDD:204617"
     gene            414529..415413
                     /locus_tag="BCG_0355"
                     /db_xref="GeneID:4697754"
     CDS             414529..415413
                     /locus_tag="BCG_0355"
                     /EC_number="3.2.1.-"
                     /note="Differs from Rv0315 by 1aa, T260K"
                     /codon_start=1
                     /transl_table=11
                     /product="beta-1,3-glucanase"
                     /protein_id="YP_976453.1"
                     /db_xref="GI:121636230"
                     /db_xref="GeneID:4697754"
                     /translation="MLMPEMDRRRMMMMAGFGALAAALPAPTAWADPSRPAAPAGPTP
                     APAAPAAATGGLLFHDEFDGPAGSVPDPSKWQVSNHRTPIKNPVGFDRPQFFGQYRDS
                     RQNVFLDGNSNLVLRATREGNRYFGGLVHGLWRGGIGTTWEARIKFNCLAPGMWPAWW
                     LSNDDPGRSGEIDLIEWYGNGTWPSGTTVHANPDGTAFETCPIGVDGGWHNWRVTWNP
                     SGMYFWLDYADGIEPYFSVPATGIEDLNEPIREWPFNDPGYTVFPVLNLAVGGSGGGD
                     PATGSYPQEMLVDWVRVF"
     misc_feature    414694..415410
                     /locus_tag="BCG_0355"
                     /note="Beta-glucanase/Beta-glucan synthetase [Carbohydrate
                     transport and metabolism]; Region: SKN1; COG2273"
                     /db_xref="CDD:225182"
     misc_feature    414700..415410
                     /locus_tag="BCG_0355"
                     /note="Laminarinase, member of the glycosyl hydrolase
                     family 16; Region: GH16_laminarinase_like; cd08023"
                     /db_xref="CDD:185693"
     misc_feature    order(414937..414939,414994..414996,415006..415008,
                     415039..415041,415045..415047,415054..415056,
                     415096..415098)
                     /locus_tag="BCG_0355"
                     /note="active site"
                     /db_xref="CDD:185693"
     misc_feature    order(415039..415041,415045..415047,415054..415056)
                     /locus_tag="BCG_0355"
                     /note="catalytic residues [active]"
                     /db_xref="CDD:185693"
     gene            415462..416076
                     /locus_tag="BCG_0356"
                     /db_xref="GeneID:4695701"
     CDS             415462..416076
                     /locus_tag="BCG_0356"
                     /EC_number="5.3.3.-"
                     /codon_start=1
                     /transl_table=11
                     /product="muconolactone isomerase"
                     /protein_id="YP_976454.1"
                     /db_xref="GI:121636231"
                     /db_xref="GeneID:4695701"
                     /translation="MEFLVTMTTRVPDSMPADAVERVRAREAARSRELAAQGKLLRLW
                     RPPLRPGEWRTLGLFAADDNGELEQLLASMPPRSWRTDDVTPLGAHPNDPVGQGITIA
                     PGKGPEFLIATTIMVPPGTPAQVVDDTVAREARRAPELAGRGHLVRLWALPDGPDGQR
                     TLGLWRARDPGELMAILESLPLAGWMTIETTPLSPHPDDPIRMP"
     misc_feature    415462..415776
                     /locus_tag="BCG_0356"
                     /note="Muconolactone delta-isomerase; Region: MIase;
                     cl01992"
                     /db_xref="CDD:242825"
     misc_feature    415786..416052
                     /locus_tag="BCG_0356"
                     /note="Muconolactone delta-isomerase; Region: MIase;
                     cl01992"
                     /db_xref="CDD:242825"
     gene            complement(416100..416870)
                     /gene="glpQ2"
                     /locus_tag="BCG_0357c"
                     /db_xref="GeneID:4698721"
     CDS             complement(416100..416870)
                     /gene="glpQ2"
                     /locus_tag="BCG_0357c"
                     /EC_number="3.1.4.46"
                     /codon_start=1
                     /transl_table=11
                     /product="glycerophosphoryl diester phosphodiesterase
                     glpQ2"
                     /protein_id="YP_976455.1"
                     /db_xref="GI:121636232"
                     /db_xref="GeneID:4698721"
                     /translation="MEFLRHGGRIAMAHRGFTSFRLPMNSMGAFQEAAKLGFRYIETD
                     VRATRDGVAVILHDRRLAPGVGLSGAVDRLDWRDVRKAQLGAGQSIPTLEDLLTALPD
                     MRVNIDIKAASAIEPTVNVIERCNAHNRVLIGSFSERRRRRALRLLTKRVASSAGTGA
                     LLAWLTARPLGSRAYAWRMMRDIDCVQLPSRLGGVPVITPARVRGFHAAGRQVHAWTV
                     DEPDVMHTLLDMDVDGIITDRADLLRDVLIARGEWDGA"
     misc_feature    complement(416130..416840)
                     /gene="glpQ2"
                     /locus_tag="BCG_0357c"
                     /note="Glycerophosphodiester phosphodiesterase domain of
                     Streptomyces coelicolor cytoplasmic phosphodiesterases
                     UgpQ2 and similar proteins; Region:
                     GDPD_cytoplasmic_ScUgpQ2_like; cd08561"
                     /db_xref="CDD:176504"
     misc_feature    complement(416145..416831)
                     /gene="glpQ2"
                     /locus_tag="BCG_0357c"
                     /note="Glycerophosphoryl diester phosphodiesterase family;
                     Region: GDPD; pfam03009"
                     /db_xref="CDD:251672"
     misc_feature    complement(order(416223..416225,416469..416471,
                     416547..416549,416700..416702,416739..416741,
                     416745..416747,416829..416831))
                     /gene="glpQ2"
                     /locus_tag="BCG_0357c"
                     /note="putative active site [active]"
                     /db_xref="CDD:176504"
     misc_feature    complement(order(416700..416702,416829..416831))
                     /gene="glpQ2"
                     /locus_tag="BCG_0357c"
                     /note="catalytic site [active]"
                     /db_xref="CDD:176504"
     misc_feature    complement(order(416547..416549,416739..416741,
                     416745..416747))
                     /gene="glpQ2"
                     /locus_tag="BCG_0357c"
                     /note="putative metal binding site [ion binding]; other
                     site"
                     /db_xref="CDD:176504"
     gene            complement(417131..417201)
                     /gene="tRNA-Gly"
                     /locus_tag="BCG_t02"
                     /db_xref="GeneID:4696568"
     tRNA            complement(417131..417201)
                     /gene="tRNA-Gly"
                     /locus_tag="BCG_t02"
                     /product="tRNA-Gly"
                     /note="glyU, len: 71 nt. Equivalent to glyU, len: 71 nt,
                     from Mycobacterium tuberculosis strain H37Rv, (100.0%
                     identity in 71 nt overlap). tRNA-Gly, anticodon ccc"
                     /anticodon=(pos:complement(417167..417169),aa:Gly,seq:ccc)
                     /codon_recognized="GGG"
                     /db_xref="GeneID:4696568"
     gene            complement(417232..418026)
                     /locus_tag="BCG_0358c"
                     /db_xref="GeneID:4696329"
     CDS             complement(417232..418026)
                     /locus_tag="BCG_0358c"
                     /note="Differs from Rv0318c by 1aa, A223G"
                     /codon_start=1
                     /transl_table=11
                     /product="integral membrane protein"
                     /protein_id="YP_976456.1"
                     /db_xref="GI:121636233"
                     /db_xref="GeneID:4696329"
                     /translation="MSLAVTMFKRARAEIFDRNREVGISNVTTAASLVTFPVLAGILG
                     GVVPSVRTPSAAMVSGVQHFAAGIVMAAVAGEVLPDLRSRGPLWLIVVGFSAGVAVLV
                     ALRRFDGHGEHQDGDDVGELPVGFLTVVAVDLFIDGLLVATGATVSSRTAIIITIALT
                     VEVLFLGLAVALRLAGSGMPRIRAAATTSALSLVIAVGGVSGAVALGRAGNTVLTLVL
                     AFAAAALLWLVVEELLVEAHETPERPWMAVMFFAGFLILYGLGVME"
     misc_feature    complement(417238..418011)
                     /locus_tag="BCG_0358c"
                     /note="Predicted divalent heavy-metal cations transporter
                     [Inorganic ion transport and metabolism]; Region: COG0428"
                     /db_xref="CDD:223505"
     gene            418075..418743
                     /gene="pcp"
                     /locus_tag="BCG_0359"
                     /db_xref="GeneID:4696347"
     CDS             418075..418743
                     /gene="pcp"
                     /locus_tag="BCG_0359"
                     /EC_number="3.4.19.3"
                     /note="catalyzes the removal of 5-oxoproline from various
                     penultimate amino acid residues except L-proline"
                     /codon_start=1
                     /transl_table=11
                     /product="pyrrolidone-carboxylate peptidase"
                     /protein_id="YP_976457.1"
                     /db_xref="GI:121636234"
                     /db_xref="GeneID:4696347"
                     /translation="MSKVLVTGFGPYGVTPVNPAQLTAEELDGRTIAGATVISRIVPN
                     TFFESIAAAQQAIAEIEPALVIMLGEYPGRSMITVERLAQNVNDCGRYGLADCAGRVL
                     VGEPTDPAGPVAYHATVPVRAMVLAMRKAGVPADVSDAAGTFVCNHLMYGVLHHLAQK
                     GLPVRAGWIHLPCLPSVAALDHNLGVPSMSVQTAVAGVTAGIEAAIRQSADIREPIPS
                     RLQI"
     misc_feature    418081..418674
                     /gene="pcp"
                     /locus_tag="BCG_0359"
                     /note="Pyroglutamyl peptidase (PGP) type I, also known as
                     pyrrolidone carboxyl peptidase (pcp) type I:  Enzymes
                     responsible for cleaving pyroglutamate (pGlu) from the
                     N-terminal end of specialized proteins. The N-terminal
                     pGlu protects these proteins from...; Region:
                     Peptidase_C15; cd00501"
                     /db_xref="CDD:238279"
     misc_feature    order(418099..418101,418108..418110,418204..418206,
                     418504..418512)
                     /gene="pcp"
                     /locus_tag="BCG_0359"
                     /note="putative substrate binding pocket [chemical
                     binding]; other site"
                     /db_xref="CDD:238279"
     misc_feature    order(418294..418302,418459..418461,418468..418482,
                     418597..418602,418606..418608,418633..418638,
                     418642..418644)
                     /gene="pcp"
                     /locus_tag="BCG_0359"
                     /note="AC domain interface; other site"
                     /db_xref="CDD:238279"
     misc_feature    order(418312..418314,418510..418512,418582..418584)
                     /gene="pcp"
                     /locus_tag="BCG_0359"
                     /note="catalytic triad [active]"
                     /db_xref="CDD:238279"
     misc_feature    order(418315..418320,418330..418332,418336..418338,
                     418342..418344,418381..418386,418411..418422,
                     418438..418440,418489..418494,418501..418503)
                     /gene="pcp"
                     /locus_tag="BCG_0359"
                     /note="AB domain interface; other site"
                     /db_xref="CDD:238279"
     misc_feature    418642..418644
                     /gene="pcp"
                     /locus_tag="BCG_0359"
                     /note="interchain disulfide; other site"
                     /db_xref="CDD:238279"
     gene            418815..419477
                     /locus_tag="BCG_0360"
                     /db_xref="GeneID:4698420"
     CDS             418815..419477
                     /locus_tag="BCG_0360"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_976458.1"
                     /db_xref="GI:121636235"
                     /db_xref="GeneID:4698420"
                     /translation="MGRHELARDRRKSSAVLAAVLAPAAVFFATGGDVSTLAARADAN
                     PVLGDDAPCCVQIVPVAPLAFSSQISGGEIGTGLAASQFASASRWRIVSRYLPVGVAP
                     EQGLQVKTVLTARSISAAFPEIREIGGVRPDALRWHPNGLALDVMVPNPGTAEGIALG
                     NEIVAFVLKNATRFGMQDVIWRGAYYTPNGARTTGAGHYDHIHITTVGGGYPTGEELY
                     IR"
     gene            419509..420081
                     /gene="dcd"
                     /locus_tag="BCG_0361"
                     /db_xref="GeneID:4697227"
     CDS             419509..420081
                     /gene="dcd"
                     /locus_tag="BCG_0361"
                     /EC_number="3.5.4.13"
                     /note="Catalyzes the formation of dUTP from dCTP in
                     thymidylate biosynthesis"
                     /codon_start=1
                     /transl_table=11
                     /product="deoxycytidine triphosphate deaminase"
                     /protein_id="YP_976459.1"
                     /db_xref="GI:121636236"
                     /db_xref="GeneID:4697227"
                     /translation="MLLSDRDLRAEISSGRLGIDPFDDTLVQPSSIDVRLDCLFRVFN
                     NTRYTHIDPAKQQDELTSLVQPVDGEPFVLHPGEFVLGSTLELFTLPDNLAGRLEGKS
                     SLGRLGLLTHSTAGFIDPGFSGHITLELSNVANLPITLWPGMKIGQLCMLRLTSPSEH
                     PYGSSRAGSKYQGQRGPTPSRSCQNFIRST"
     misc_feature    419710..419955
                     /gene="dcd"
                     /locus_tag="BCG_0361"
                     /note="Trimeric dUTP diphosphatases; Region:
                     trimeric_dUTPase; cd07557"
                     /db_xref="CDD:143638"
     misc_feature    order(419725..419727,419740..419745,419749..419751,
                     419797..419799,419803..419820,419833..419841,
                     419857..419859,419866..419868,419887..419889,
                     419893..419895,419899..419901,419905..419907,
                     419917..419931,419938..419940,419950..419952)
                     /gene="dcd"
                     /locus_tag="BCG_0361"
                     /note="trimer interface [polypeptide binding]; other site"
                     /db_xref="CDD:143638"
     misc_feature    order(419809..419817,419857..419865,419872..419874,
                     419884..419889)
                     /gene="dcd"
                     /locus_tag="BCG_0361"
                     /note="active site"
                     /db_xref="CDD:143638"
     gene            420187..421518
                     /gene="udgA"
                     /locus_tag="BCG_0362"
                     /db_xref="GeneID:4697262"
     CDS             420187..421518
                     /gene="udgA"
                     /locus_tag="BCG_0362"
                     /EC_number="1.1.1.22"
                     /codon_start=1
                     /transl_table=11
                     /product="udp-glucose 6-dehydrogenase udgA"
                     /protein_id="YP_976460.1"
                     /db_xref="GI:121636237"
                     /db_xref="GeneID:4697262"
                     /translation="MRCSVFGTGYLGATHAVGMAQLGHEVVGVDIDPGKVAKLAGGDI
                     PFYEPGLRKLLTDNLAAGRLRFTTDYDMAADFADVHFLGVGTPQKIGEYGADLRHVHA
                     VIDALVPRLVRASILVGKSTVPVGTAAELGHRAGALAPRGVDVEIAWNPEFLREGFAV
                     HDTLNPDRIVLGVQDDSTRAEVAVRELYAPLLAAGVPFLVTDLQTAELVKVSANAFLA
                     TKISFINAISEVCEAAGADVSQLADALGYDPRIGRQCLNAGLGFGGGCLPKDIRAFMA
                     RAGELGADQALTFLREVDSINMRRRTKMVELATTACGGSLLGANIAVLGAAFKPESDD
                     VRDSPALNVAGQLQLNGATVHVYDPKALDNAHRLFPTLNYAVSVAEACERADAVLVLT
                     EWREFIDLEPADLANRVRARVIVDGRNCLDVTRWRRAGWRVFRLGVPRLGH"
     misc_feature    420187..421458
                     /gene="udgA"
                     /locus_tag="BCG_0362"
                     /note="Predicted UDP-glucose 6-dehydrogenase [Cell
                     envelope biogenesis, outer membrane]; Region: Ugd;
                     COG1004"
                     /db_xref="CDD:223936"
     misc_feature    420187..420735
                     /gene="udgA"
                     /locus_tag="BCG_0362"
                     /note="UDP-glucose/GDP-mannose dehydrogenase family, NAD
                     binding domain; Region: UDPG_MGDP_dh_N; pfam03721"
                     /db_xref="CDD:252123"
     misc_feature    order(420211..420219,420274..420279,420433..420438,
                     420493..420495)
                     /gene="udgA"
                     /locus_tag="BCG_0362"
                     /note="NAD(P) binding site [chemical binding]; other site"
                     /db_xref="CDD:133419"
     misc_feature    order(420223..420225,420235..420237,420289..420291,
                     420295..420300,420304..420312)
                     /gene="udgA"
                     /locus_tag="BCG_0362"
                     /note="LDH/MDH dimer interface [polypeptide binding];
                     other site"
                     /db_xref="CDD:133419"
     misc_feature    420793..421086
                     /gene="udgA"
                     /locus_tag="BCG_0362"
                     /note="UDP-glucose/GDP-mannose dehydrogenase family,
                     central domain; Region: UDPG_MGDP_dh; pfam00984"
                     /db_xref="CDD:250272"
     misc_feature    421150..421452
                     /gene="udgA"
                     /locus_tag="BCG_0362"
                     /note="UDP binding domain; Region: UDPG_MGDP_dh_C;
                     smart00984"
                     /db_xref="CDD:214954"
     gene            complement(421507..422178)
                     /locus_tag="BCG_0363c"
                     /db_xref="GeneID:4696865"
     CDS             complement(421507..422178)
                     /locus_tag="BCG_0363c"
                     /note="Differs from Rv0323c by 1aa, G142S"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_976461.1"
                     /db_xref="GI:121636238"
                     /db_xref="GeneID:4696865"
                     /translation="MNSCNRLPCAHEVLAVFAHPDDESFGLGAVLGDFTAQGTRLRGL
                     CFTHGEASTLGRTDRNLGEVRREELAAAAQVLGVDHVQLLAYPDNGLAQIPLNELTQR
                     VVDALAGADLLLVFDDNGVTGHPDHRRATEAALAAASTPGIPVLAWALPQPIADRLNA
                     EFSASFGGRGHGHLDIMIEVDRSRQLAAIGCHFTQSADNPVLWRRLELLGDREYLRWL
                     RRSVP"
     misc_feature    complement(421519..422178)
                     /locus_tag="BCG_0363c"
                     /note="Uncharacterized proteins, LmbE homologs [Function
                     unknown]; Region: COG2120"
                     /db_xref="CDD:225031"
     gene            422279..422959
                     /locus_tag="BCG_0364"
                     /db_xref="GeneID:4696364"
     CDS             422279..422959
                     /locus_tag="BCG_0364"
                     /note="Differs from Rv0324 by 1aa, A168T"
                     /codon_start=1
                     /transl_table=11
                     /product="ArsR family transcriptional regulator"
                     /protein_id="YP_976462.1"
                     /db_xref="GI:121636239"
                     /db_xref="GeneID:4696364"
                     /translation="MAGQSDRKAALLDQVARVGKALANGRRLQILDLLAQGERAVEAI
                     ATATGMNLTTASANLQALKSGGLVEARREGTRQYYRIAGEDVARLFALVQVVADEHLA
                     DVAVAAADVLGSPEDAITRAELLRRREAGEVTLVDVRPHEEYQAGHIPGAINIPIAEL
                     ADRLAELAGDRDIVAYCRGAYCVMAPDAVRIARDAGREVKRLDDGMLEWRLAGLPVDE
                     GAPVGHGD"
     misc_feature    422333..422572
                     /locus_tag="BCG_0364"
                     /note="Arsenical Resistance Operon Repressor and similar
                     prokaryotic, metal regulated homodimeric repressors. ARSR
                     subfamily of helix-turn-helix bacterial transcription
                     regulatory proteins (winged helix topology). Includes
                     several proteins that appear to...; Region: HTH_ARSR;
                     cd00090"
                     /db_xref="CDD:238042"
     misc_feature    order(422333..422338,422342..422344,422351..422353,
                     422360..422365,422372..422377,422384..422386,
                     422474..422476,422540..422545,422549..422557,
                     422561..422569)
                     /locus_tag="BCG_0364"
                     /note="dimerization interface [polypeptide binding]; other
                     site"
                     /db_xref="CDD:238042"
     misc_feature    order(422336..422341,422351..422359,422396..422404,
                     422429..422440,422444..422449,422456..422461,
                     422465..422470,422486..422494,422507..422515)
                     /locus_tag="BCG_0364"
                     /note="putative DNA binding site [nucleotide binding];
                     other site"
                     /db_xref="CDD:238042"
     misc_feature    order(422396..422398,422405..422407,422540..422542)
                     /locus_tag="BCG_0364"
                     /note="putative Zn2+ binding site [ion binding]; other
                     site"
                     /db_xref="CDD:238042"
     misc_feature    422645..422908
                     /locus_tag="BCG_0364"
                     /note="Rhodanese Homology Domain (RHOD); an alpha beta
                     fold domain found duplicated in the rhodanese protein. The
                     cysteine containing enzymatically active version of the
                     domain is also found in the Cdc25 class of protein
                     phosphatases and a variety of proteins...; Region: RHOD;
                     cd00158"
                     /db_xref="CDD:238089"
     misc_feature    422807..422809
                     /locus_tag="BCG_0364"
                     /note="active site residue [active]"
                     /db_xref="CDD:238089"
     gene            422966..423655
                     /locus_tag="BCG_0365"
                     /db_xref="GeneID:4695771"
     CDS             422966..423655
                     /locus_tag="BCG_0365"
                     /note="In Mycobacterium tuberculosis strain H37Rv, Rv0325
                     and Rv0326 exist as 2 genes. In Mycobacterium bovis BCG
                     Pasteur, and Mycobacterium bovis, the absence of a stop
                     codon between Rv0325 and Rv0326 due to a single base
                     transition (t-c) leads to single product"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_976463.1"
                     /db_xref="GI:121636240"
                     /db_xref="GeneID:4695771"
                     /translation="MGPKGSLRLVKRQPELLVAQHEHWQDTYRAHPVLYGTRPSEPGV
                     YAAEVFNADGVQRVLELAAGHGRDTLYFAGQGFTVVATDFSDVAVAQLRRSAQARGVS
                     ARVQPIVHDLRQPLPVKTGSIDGAFAHMALCMALSTSEIHAVVAEVGRVLRPGGKFIY
                     TVRHTGDAHYGAGQAHGDDIFECAGFAVHFFRRELVARLATGWVLEEVHDFEEGELPR
                     RLWRVTVTKPA"
     misc_feature    423134..423457
                     /locus_tag="BCG_0365"
                     /note="S-adenosylmethionine-dependent methyltransferases
                     (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes
                     that use S-adenosyl-L-methionine (SAM or AdoMet) as a
                     substrate for methyltransfer, creating the product
                     S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases;
                     cd02440"
                     /db_xref="CDD:100107"
     misc_feature    order(423146..423166,423212..423217,423293..423301,
                     423350..423352)
                     /locus_tag="BCG_0365"
                     /note="S-adenosylmethionine binding site [chemical
                     binding]; other site"
                     /db_xref="CDD:100107"
     gene            complement(423623..424972)
                     /gene="cyp135A1"
                     /locus_tag="BCG_0366c"
                     /db_xref="GeneID:4698342"
     CDS             complement(423623..424972)
                     /gene="cyp135A1"
                     /locus_tag="BCG_0366c"
                     /EC_number="1.14.-.-"
                     /note="Differs from Rv0327c by 1aa, Y100H"
                     /codon_start=1
                     /transl_table=11
                     /product="cytochrome P450 135A1 cyp135A1"
                     /protein_id="YP_976464.1"
                     /db_xref="GI:121636241"
                     /db_xref="GeneID:4698342"
                     /translation="MASTLTTGLPPGPRLPRYLQSVLYLRFREWFLPAMHRKYGDVFS
                     LRVPPYADNLVVYTRPEHIKEIFAADPRSLHAGEGNHILGFVMGEHSVLMTDEAEYAR
                     MRSLLMPAFTRAALRGYRDMIASVAREHITRWRPHATINSLDHMNALTLDIILRVVFG
                     VTDPKVKAELTSRLQQIINIHPAILAGVPYPSLKRMNPWKRFFHNQTKIDEILYREIA
                     SRRIDSDLTARTDVLSRLLQTKDTPTKPLTDAELRDQLITLLLAGHETTAAALSWTLW
                     ELAHAPEIQSQVVWAAVGGDDGFLEAVLKEGMRRHTVIASTARKVTAPAEIGGWRLPA
                     GTVVNTSILLAHASEVSHPKPTEFRPSRFLDGSVAPNTWLPFGGGVRRCLGFGFALTE
                     GAVILQEIFRRFTITAAGPSKGETPLVRNITTVPKHGAHLRLIPQRRLGGLGDSDPP"
     misc_feature    complement(423659..424945)
                     /gene="cyp135A1"
                     /locus_tag="BCG_0366c"
                     /note="Cytochrome P450 [Secondary metabolites
                     biosynthesis, transport, and catabolism]; Region: CypX;
                     COG2124"
                     /db_xref="CDD:225035"
     gene            425038..425640
                     /locus_tag="BCG_0367"
                     /db_xref="GeneID:4697064"
     CDS             425038..425640
                     /locus_tag="BCG_0367"
                     /codon_start=1
                     /transl_table=11
                     /product="TetR family transcriptional regulator"
                     /protein_id="YP_976465.1"
                     /db_xref="GI:121636242"
                     /db_xref="GeneID:4697064"
                     /translation="MQQQRTNRDKLLDGALACLRERGYGNTSSRDIARAAGVNIASIN
                     YHFGSKDALLDDALGRCFSTWNQRVQEAFDHSRAAGPAGQILAVLEATVDSFEQIRPA
                     VYACVESYAPALRSEALRERLAAGYADVRQHSVDLAGAALAGTDIAPPENLSTIVSVL
                     MAVIDGLMIQWIADPSATPRSTEVIRALASIGAVVTSQLR"
     misc_feature    425059..425634
                     /locus_tag="BCG_0367"
                     /note="transcriptional repressor BetI; Region:
                     betaine_BetI; TIGR03384"
                     /db_xref="CDD:132427"
     misc_feature    425068..425202
                     /locus_tag="BCG_0367"
                     /note="Bacterial regulatory proteins, tetR family; Region:
                     TetR_N; pfam00440"
                     /db_xref="CDD:249860"
     misc_feature    425278..425604
                     /locus_tag="BCG_0367"
                     /note="Bacterial transcriptional repressor; Region:
                     TetR_C_6; pfam13977"
                     /db_xref="CDD:258229"
     gene            complement(425621..426247)
                     /locus_tag="BCG_0368c"
                     /db_xref="GeneID:4696759"
     CDS             complement(425621..426247)
                     /locus_tag="BCG_0368c"
                     /note="Differs from Rv0329c by 1aa, S129W"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_976466.1"
                     /db_xref="GI:121636243"
                     /db_xref="GeneID:4696759"
                     /translation="MRLTHPARRYLSSQAARPTGAFGRLLGRIWRAETADVNRIAVEL
                     LAPGPGERVCEIGFGPGRTLGLLAAAGAQVSGVEVSTTMIAIAAHHNAKAIAAGLISL
                     YHGDGVTLPVADHSLDKVLGVHNFYFSPDPRASLCDIARALRPGGRLVLTSISDDQPL
                     AARFDPAIYRVPPTLDTAAWLGAAGFIDVGIKRSADHPATVWFTATAT"
     misc_feature    complement(425792..426094)
                     /locus_tag="BCG_0368c"
                     /note="S-adenosylmethionine-dependent methyltransferases
                     (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes
                     that use S-adenosyl-L-methionine (SAM or AdoMet) as a
                     substrate for methyltransfer, creating the product
                     S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases;
                     cd02440"
                     /db_xref="CDD:100107"
     misc_feature    complement(order(425879..425881,425927..425935,
                     426011..426016,426062..426082))
                     /locus_tag="BCG_0368c"
                     /note="S-adenosylmethionine binding site [chemical
                     binding]; other site"
                     /db_xref="CDD:100107"
     gene            complement(426274..427014)
                     /locus_tag="BCG_0369c"
                     /db_xref="GeneID:4697221"
     CDS             complement(426274..427014)
                     /locus_tag="BCG_0369c"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_976467.1"
                     /db_xref="GI:121636244"
                     /db_xref="GeneID:4697221"
                     /translation="MARSIPADRFSAIVAASARVFIAHGYQRTQVQDVADALALAKGT
                     LYGYAQGKAALFAAAVRYGDAQEALPLASELPVAAPVAGEIAAVVSARLAGEVTDMRL
                     THALRATLPPGATTGDARAELAGIVTDLYSRLARHRIALKLVDRCAPELPDLAEVWFG
                     TGRNAQVDAVQAYLVHRERAGLLILPGPAPMVARTIVELCALWAVHLHFDPSPEPWSI
                     VQPGVIDDDAIAATLAEFVVRATTASSD"
     misc_feature    complement(<426550..426981)
                     /locus_tag="BCG_0369c"
                     /note="Transcriptional regulator [Transcription]; Region:
                     AcrR; COG1309"
                     /db_xref="CDD:224228"
     misc_feature    complement(426838..426978)
                     /locus_tag="BCG_0369c"
                     /note="Bacterial regulatory proteins, tetR family; Region:
                     TetR_N; pfam00440"
                     /db_xref="CDD:249860"
     gene            427128..428294
                     /locus_tag="BCG_0370"
                     /db_xref="GeneID:4698412"
     CDS             427128..428294
                     /locus_tag="BCG_0370"
                     /EC_number="1.-.-.-"
                     /codon_start=1
                     /transl_table=11
                     /product="dehydrogenase/reductase"
                     /protein_id="YP_976468.1"
                     /db_xref="GI:121636245"
                     /db_xref="GeneID:4698412"
                     /translation="MSKTVLILGAGVGGLTTADTLRQLLPPEDRIILVDRSFDGTLGL
                     SLLWVLRGWRRPDDVRVRPTAASLPGVEMVTATVAHIDIAAQVVHTDNSVIGYDALVI
                     ALGAALNTDAVPGLSDALDADVAGQFYTLDGAAELRAKVEALEHGRIAVAIAGVPFKC
                     PAAPFEAAFLIAAQLGDRYATGTVQIDTFTPDPLPMPVAGPEVGEALVSMLKDHGVGF
                     HPRKALARVDEAARTMHFGDGTSEPFDLLAVVPPHVPSAAARSAGLSESGWIPVDPRT
                     LSTSADNVWAIGDATVLTLPNGKPLPKAAVFAEAQAAVVAHGVARHLGYDVAERHFTG
                     TGACYVETGDHQAAKGDGDFFAPSAPSVTLYPPSREFHEEKVAQELAWLTRWKT"
     misc_feature    427140..428000
                     /locus_tag="BCG_0370"
                     /note="Pyridine nucleotide-disulphide oxidoreductase;
                     Region: Pyr_redox_2; pfam07992"
                     /db_xref="CDD:254568"
     gene            428369..429154
                     /locus_tag="BCG_0371"
                     /db_xref="GeneID:4696350"
     CDS             428369..429154
                     /locus_tag="BCG_0371"
                     /note="Differs from Rv0332 by 1aa, G198E"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_976469.1"
                     /db_xref="GI:121636246"
                     /db_xref="GeneID:4696350"
                     /translation="MRKPASSLAKVDYSSAYLEQTHAFGELIRNVDQSTPVPTCPGWS
                     LGQLFRHVGRGDRWAAQIVRDRLDHFLDPRSVEGGKPPPDPDDAISWLYGGARLLVDA
                     VEQTGVETPVWTFLGPRPAGWWVRRRLHEVAVHRADVAITVGGEFTLEPNVAADGISE
                     FLERIAVQAGSGGTPLPLEDDDTLHLHATDPGLLEAGGWTVRRDERGVTWSHRHGKGA
                     VALRGGATELLLAMVRRLSVADTGIELLGDAGVWQKWLDRTPL"
     misc_feature    428414..429073
                     /locus_tag="BCG_0371"
                     /note="uncharacterized Actinobacterial protein TIGR03083;
                     Region: TIGR03083"
                     /db_xref="CDD:234103"
     misc_feature    428414..428788
                     /locus_tag="BCG_0371"
                     /note="Mycothiol maleylpyruvate isomerase N-terminal
                     domain; Region: MDMPI_N; pfam11716"
                     /db_xref="CDD:256569"
     misc_feature    428825..429127
                     /locus_tag="BCG_0371"
                     /note="MDMPI C-terminal domain; Region: MDMPI_C;
                     pfam07398"
                     /db_xref="CDD:254187"
     gene            429181..429555
                     /locus_tag="BCG_0372"
                     /db_xref="GeneID:4697767"
     CDS             429181..429555
                     /locus_tag="BCG_0372"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_976470.1"
                     /db_xref="GI:121636247"
                     /db_xref="GeneID:4697767"
                     /translation="MTTSEIATVLAWHDALNAADIETLVALSTDDIDIGDAHGAVQGH
                     DALRGWASSLTTTAELGRMYVHHGVVVVEQKITSGEDPGIARTGAAAFRVVQDHVASV
                     FRHEDLASALAATELTEDDLVD"
     misc_feature    429205..429501
                     /locus_tag="BCG_0372"
                     /note="SnoaL-like domain; Region: SnoaL_2; pfam12680"
                     /db_xref="CDD:257217"
     gene            429585..430451
                     /gene="rmlA"
                     /locus_tag="BCG_0373"
                     /db_xref="GeneID:4696702"
     CDS             429585..430451
                     /gene="rmlA"
                     /locus_tag="BCG_0373"
                     /EC_number="2.7.7.24"
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-1-phosphate thymidylyltransferase rmlA"
                     /protein_id="YP_976471.1"
                     /db_xref="GI:121636248"
                     /db_xref="GeneID:4696702"
                     /translation="MRGIILAGGSGTRLYPITMGISKQLLPVYDKPMIYYPLTTLMMA
                     GIRDIQLITTPHDAPGFHRLLGDGAHLGVNISYATQDQPDGLAQAFVIGANHIGADSV
                     ALVLGDNIFYGPGLGTSLKRFQSISGGAIFAYWVANPSAYGVVEFGAEGMALSLEEKP
                     VTPKSNYAVPGLYFYDNDVIEIARGLKKSARGEYEITEVNQVYLNQGRLAVEVLARGT
                     AWLDTGTFDSLLDAADFVRTLERRQGLKVSIPEEVAWRMGWIDDEQLVQRARALVKSG
                     YGNYLLELLERN"
     misc_feature    429585..430301
                     /gene="rmlA"
                     /locus_tag="BCG_0373"
                     /note="G1P_TT_short is the short form of
                     glucose-1-phosphate thymidylyltransferase; Region:
                     G1P_TT_short; cd02538"
                     /db_xref="CDD:133019"
     misc_feature    429588..430442
                     /gene="rmlA"
                     /locus_tag="BCG_0373"
                     /note="glucose-1-phosphate thymidylyltransferase, short
                     form; Region: rmlA; TIGR01207"
                     /db_xref="CDD:130274"
     misc_feature    order(429600..429602,429606..429611,429822..429824,
                     429831..429842,429906..429908,430011..430013,
                     430056..430061,430089..430091,430173..430175)
                     /gene="rmlA"
                     /locus_tag="BCG_0373"
                     /note="substrate binding site; other site"
                     /db_xref="CDD:133019"
     misc_feature    order(429618..429620,429627..429635,429642..429647,
                     429657..429665,429669..429680,429687..429689,
                     429762..429764,429918..429923,429984..429995,
                     430005..430010,430242..430250,430260..430265,
                     430272..430274,430281..430289,430296..430301)
                     /gene="rmlA"
                     /locus_tag="BCG_0373"
                     /note="tetramer interface; other site"
                     /db_xref="CDD:133019"
     gene            complement(430462..430977)
                     /gene="PE6"
                     /locus_tag="BCG_0374c"
                     /db_xref="GeneID:4695583"
     CDS             complement(430462..430977)
                     /gene="PE6"
                     /locus_tag="BCG_0374c"
                     /note="Differs from Rv0335c and Mb0340 by 1aa P131T"
                     /codon_start=1
                     /transl_table=11
                     /product="PE family protein"
                     /protein_id="YP_976472.1"
                     /db_xref="GI:121636249"
                     /db_xref="GeneID:4695583"
                     /translation="MRSMGFLHRACRAPSSLPAPLMARPGRSVLARPAATPPGPLCAT
                     TRPRPPQGNQPPASRISNFPPKRHKTRVLAAAEDEVSAAVAALISAHGRRHHSLNNQA
                     AAFHGQFAQNLNVGAGSCASAETTADAPPQALLGPADRQRRQRRAVRQWLVRWAAHPG
                     RATRGFHNHRQ"
     misc_feature    complement(430597..>430770)
                     /gene="PE6"
                     /locus_tag="BCG_0374c"
                     /note="PE family; Region: PE; pfam00934"
                     /db_xref="CDD:250239"
     gene            431119..432630
                     /locus_tag="BCG_0375"
                     /db_xref="GeneID:4696203"
     CDS             431119..432630
                     /locus_tag="BCG_0375"
                     /note="Differs from Rv0336 by 1aa, H496P"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_976473.1"
                     /db_xref="GI:121636250"
                     /db_xref="GeneID:4696203"
                     /translation="MPSPEAIAHFDERFECHAPRTTRVSAAFIDRICSATRAENRAAA
                     AQLVALGELFAYRWSRCGGREEWVMDTMAAVAAEVAAALRISQGLAASRLRYARAMRE
                     RLPKTAEVFSAGDIGYLMFATIVYRTDLIVDPDVLAAVDAQLAANVARWPSMTKARLA
                     GQVDKIVARADADAVRRRKEYQAQRQFWVGESQDGVCQIGGSLLAVDAHALDARLSAL
                     AGTVCEHDPRSREQRRADALGALAGGADRLGCGCGRADCAAGKRPAAPPVVIHLIAEA
                     ATINGTGSAPASQMNADGLITAELVAELAKTATLVPLVHPGDAPPEPGYAPSKALADF
                     VRCRDLTCRWPGCDEPATNCDLDHTIPYAAGGPTHASNLKCYCRTHHLVKTFWGWRDQ
                     QLPDGTLILTSPSGHTYVSTPGSALLFPSLCHFSGGIPAPEADPPYDHCDQRTAMMPK
                     RRRTRAQDRAYRIATERRQNHAARQRAQVLTQTAAATDTHGPPPDHNDDPPPF"
     misc_feature    431215..432135
                     /locus_tag="BCG_0375"
                     /note="Domain of unknown function (DUF222); Region:
                     DUF222; pfam02720"
                     /db_xref="CDD:251494"
     misc_feature    432130..432273
                     /locus_tag="BCG_0375"
                     /note="HNH nucleases; HNH endonuclease signature which is
                     found in viral, prokaryotic, and eukaryotic proteins. The
                     alignment includes members of the large group of homing
                     endonucleases, yeast intron 1 protein, MutS, as well as
                     bacterial colicins, pyocins, and...; Region: HNHc;
                     cd00085"
                     /db_xref="CDD:238038"
     misc_feature    order(432181..432183,432187..432195,432199..432201,
                     432232..432237,432247..432252,432259..432261,
                     432271..432273)
                     /locus_tag="BCG_0375"
                     /note="active site"
                     /db_xref="CDD:238038"
     gene            complement(432800..434089)
                     /gene="aspC"
                     /locus_tag="BCG_0376c"
                     /db_xref="GeneID:4697963"
     CDS             complement(432800..434089)
                     /gene="aspC"
                     /locus_tag="BCG_0376c"
                     /EC_number="2.6.1.2"
                     /note="broad specificity; family IV; in Corynebacterium
                     glutamicum this protein can use glutamate,
                     2-aminobutyrate, and aspartate as amino donors and
                     pyruvate as the acceptor"
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase"
                     /protein_id="YP_976474.1"
                     /db_xref="GI:121636251"
                     /db_xref="GeneID:4697963"
                     /translation="MDNDGTIVDVTTHQLPWHTASHQRQRAFAQSAKLQDVLYEIRGP
                     VHQHAARLEAEGHRILKLNIGNPAPFGFEAPDVIMRDIIQALPYAQGYSDSQGILSAR
                     RAVVTRYELVPGFPRFDVDDVYLGNGVSELITMTLQALLDNGDQVLIPSPDYPLWTAS
                     TSLAGGTPVHYLCDETQGWQPDIADLESKITERTKALVVINPNNPTGAVYSCEILTQM
                     VDLARKHQLLLLADEIYDKILYDDAKHISLASIAPDMLCLTFNGLSKAYRVAGYRAGW
                     LAITGPKEHASSFIEGIGLLANMRLCPNVPAQHAIQVALGGHQSIEDLVLPGGRLLEQ
                     RDIAWTKLNEIPGVSCVKPAGALYAFPRLDPEVYDIDDDEQLVLDLLLSEKILVTQGT
                     GFNWPAPDHLRLVTLPWSRDLAAAIERLGNFLVSYRQ"
     misc_feature    complement(432803..434017)
                     /gene="aspC"
                     /locus_tag="BCG_0376c"
                     /note="aminotransferase AlaT; Validated; Region: PRK09265"
                     /db_xref="CDD:181738"
     misc_feature    complement(432827..433912)
                     /gene="aspC"
                     /locus_tag="BCG_0376c"
                     /note="Aspartate aminotransferase family. This family
                     belongs to pyridoxal phosphate (PLP)-dependent aspartate
                     aminotransferase superfamily (fold I). Pyridoxal phosphate
                     combines with an alpha-amino acid to form a compound
                     called a Schiff base or aldimine...; Region: AAT_like;
                     cd00609"
                     /db_xref="CDD:99734"
     misc_feature    complement(order(433271..433273,433295..433300,
                     433304..433306,433385..433387,433478..433480,
                     433628..433630,433700..433708))
                     /gene="aspC"
                     /locus_tag="BCG_0376c"
                     /note="pyridoxal 5'-phosphate binding site [chemical
                     binding]; other site"
                     /db_xref="CDD:99734"
     misc_feature    complement(order(433160..433162,433169..433171,
                     433271..433279,433406..433408,433598..433600,
                     433697..433699))
                     /gene="aspC"
                     /locus_tag="BCG_0376c"
                     /note="homodimer interface [polypeptide binding]; other
                     site"
                     /db_xref="CDD:99734"
     misc_feature    complement(433295..433297)
                     /gene="aspC"
                     /locus_tag="BCG_0376c"
                     /note="catalytic residue [active]"
                     /db_xref="CDD:99734"
     gene            complement(434120..436768)
                     /locus_tag="BCG_0377c"
                     /db_xref="GeneID:4695459"
     CDS             complement(434120..436768)
                     /locus_tag="BCG_0377c"
                     /EC_number="1.-.-.-"
                     /note="Differs from Rv0338c by 2aa, G506R, V621A"
                     /codon_start=1
                     /transl_table=11
                     /product="iron-sulfur-binding reductase"
                     /protein_id="YP_976475.1"
                     /db_xref="GI:121636252"
                     /db_xref="GeneID:4695459"
                     /translation="MTTQTLIRLILGMSMTAVVGVFALRRVWWLYKLVMSGQPASGRT
                     DNLGTRIWTQISEVLGQRRLLKWSIPGLAHFFTMWGFFILLTVYIEAYGLLFEERFHI
                     PVIGRWDALGFLQDFFATAVFLGITTFAIIRILRNPREIGRSSRFYGSHNGGAWLVLL
                     MIFNVIWTYVLVRGSAVNNGTLPYGNGAFLSQLFGAILRPLGQPANEIIETTALLLHI
                     GVMLAFLILVLHSKHLHIFLAPINVTFKRLPDGLGPLLPLEADGKPIDFENPSEDAVF
                     GRGKIEDFTWKGMLDFATCTECGRCQSQCPAWNTGKPLSPKLVIMDLRDHWMAKAPYI
                     LGQKDASAGGEAGHQEHHHVPESGFGRVPGHGPEQATRPLVGTEEQGGVIDPDVLWSC
                     VTCGACVEQCPVDIEHVDHIVDMRRYQVMMESEFPSELSVLFKNLETKGNPWGQNASD
                     RTNWIDEVDFDVPVYGQDVDSFDGYEYLFWVGCAGAYDDKAKKTTKAVAELLAVAGVK
                     YLVLGAGETCNGDSARRSGNEFLFQQLAQQAVETLDGLFEGVETVDRKIVVTCPHCFN
                     TIGKEYRQLGANYTVLHHTQLLNRLVRDKRLVPVTPVSQDITYHDPCYLGRHNKVYEA
                     PRELIGAAGASLTEMPRHADRSFCCGAGGARMWMEEHIGKRINHERVDEALATDATAI
                     ATACPFCRVMVTDGVNDRQEEAGRSGVEVLDVAQVLLGSLDHDKAQLPAKGTAAKQAQ
                     ERAPKAAPKAAAPVTPVEAPAEAPQAPAPAAPAAPVKGLGMAAGAKRPGAKKAAPTPA
                     APAAPAAPVKGLGIAAGAKRPGAKKTPPPAPGLAEPAAQPQPEAKPQPEPAAPPKPQT
                     DGDPAAPAAPVKGLGIARGARPPGKR"
     misc_feature    complement(434606..435916)
                     /locus_tag="BCG_0377c"
                     /note="Fe-S oxidoreductase [Energy production and
                     conversion]; Region: GlpC; COG0247"
                     /db_xref="CDD:223325"
     misc_feature    complement(435551..435886)
                     /locus_tag="BCG_0377c"
                     /note="4Fe-4S dicluster domain; Region: Fer4_8; pfam13183"
                     /db_xref="CDD:257551"
     misc_feature    complement(435062..435340)
                     /locus_tag="BCG_0377c"
                     /note="Cysteine-rich domain; Region: CCG; pfam02754"
                     /db_xref="CDD:202376"
     misc_feature    complement(434690..434950)
                     /locus_tag="BCG_0377c"
                     /note="Cysteine-rich domain; Region: CCG; pfam02754"
                     /db_xref="CDD:202376"
     misc_feature    complement(434129..>434350)
                     /locus_tag="BCG_0377c"
                     /note="Transmembrane subunit (TM) of Periplasmic Binding
                     Protein (PBP)-dependent ATP-Binding Cassette (ABC)
                     transporters which are involved in the uptake of
                     branched-chain amino acids (AAs), as well as TMs of
                     transporters involved in the uptake of...; Region:
                     TM_PBP1_branched-chain-AA_like; cl00454"
                     /db_xref="CDD:271489"
     gene            complement(436877..439375)
                     /locus_tag="BCG_0378c"
                     /db_xref="GeneID:4695752"
     CDS             complement(436877..439375)
                     /locus_tag="BCG_0378c"
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulatory protein"
                     /protein_id="YP_976476.1"
                     /db_xref="GI:121636253"
                     /db_xref="GeneID:4695752"
                     /translation="MQHRGCKNRGQAYDASVTDSLTEVPPAARRALLELANAPTVPVK
                     VLITGGIGTGKTTVLAAARDTLRRSGLTVLACPPPDGEPPETALVIDDAQLLTDTELL
                     RLTERVADSRLTVVAAAEAREHHRALRALTMALERDRPRISLGPLPVAEHLRDCTAGL
                     PFLIHAVSARAQAPAQAAKVALIERLRRLDEPTLDTLLMMSLTHELGVSDVAAALGIS
                     VTDARGLVDRAHASGLIESSHTAAFLQSVHDAIAQIVGNAHHHEVETSLLRSQLDISP
                     VSAELALRLAEHGLRDERLADILTRYAADTRDASVRCARLYRAAVHAGAKGLTVRLAD
                     ALARTGDCTAAATLADDLLSSPDATERAAAVRVAASVAVHDGNTGHAAELFGWLGPHP
                     DTMVSSAATIVFAANGDLATARATLRLKDAGPPTMAARCARNLAEGLLLTMDQPYPVA
                     MAKLGQAIATEQSLSQVIPDSPAALVTLAAIHAGDPVRARSVIGRAVRAGADPLFQRR
                     HLLLSGWIKMQEGQLPSASADVAAASAGTHLHRRDALWAAALQTAISRRTGDIGALQQ
                     HWYAAMEALAEYSLDLFALLPLGELWVAAARMRQVDQLQHTLDQALTLLDSLGNPALW
                     SNSLHWAGVHAGILANSPESVAPHGQALGAMVAHSTLAQALSDAGRTWLRVLAENVDA
                     DEVTAAARSLSHVGLTSDATRLAGQAALQTSDARVSGAMLQLARDLKLGNDFGEPPSG
                     AGDTEPASGTPPAPRQPPAGSPLSDREREVAELLLLGMPYRDIGARLFISAKTVEHHV
                     ARIRQRLGAGSRSEMLSMLRAMLAPESLTADERR"
     misc_feature    complement(436940..>437137)
                     /locus_tag="BCG_0378c"
                     /note="Response regulator containing a CheY-like receiver
                     domain and an HTH DNA-binding domain [Signal transduction
                     mechanisms / Transcription]; Region: CitB; COG2197"
                     /db_xref="CDD:225107"
     misc_feature    complement(436922..437089)
                     /locus_tag="BCG_0378c"
                     /note="C-terminal DNA-binding domain of LuxR-like
                     proteins. This domain contains a helix-turn-helix motif
                     and binds DNA. Proteins belonging to this group are
                     response regulators; some act as transcriptional
                     activators, others as transcriptional repressors. Many...;
                     Region: LuxR_C_like; cd06170"
                     /db_xref="CDD:99777"
     misc_feature    complement(order(436946..436948,436979..436993,
                     436997..437002,437006..437011,437033..437041,
                     437078..437086))
                     /locus_tag="BCG_0378c"
                     /note="DNA binding residues [nucleotide binding]"
                     /db_xref="CDD:99777"
     misc_feature    complement(order(436922..436924,436931..436933,
                     436940..436948,437039..437041,437045..437047,
                     437051..437053))
                     /locus_tag="BCG_0378c"
                     /note="dimerization interface [polypeptide binding]; other
                     site"
                     /db_xref="CDD:99777"
     gene            439561..440100
                     /locus_tag="BCG_0379"
                     /db_xref="GeneID:4697829"
     CDS             439561..440100
                     /locus_tag="BCG_0379"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_976477.1"
                     /db_xref="GI:121636254"
                     /db_xref="GeneID:4697829"
                     /translation="MANSLLDFVISLVRDPEAAARYAANPERSIAEAHLTDVTRADVN
                     SLIPVVSDSLSMSEPIGAAGGAHAGDRGNVWASGAATAALDAFAPHADAGVVQQHGAV
                     GSVLNQPTPPGPGVTPTDPRPFRAGPHETSALLTSAEIPDTTSEDGGLPTDHPAVWNH
                     PVVDPHTVEPDHHGYDIHG"
     gene            440289..441728
                     /gene="iniB"
                     /locus_tag="BCG_0380"
                     /db_xref="GeneID:4699344"
     CDS             440289..441728
                     /gene="iniB"
                     /locus_tag="BCG_0380"
                     /codon_start=1
                     /transl_table=11
                     /product="isoniazid inductible gene protein iniB"
                     /protein_id="YP_976478.1"
                     /db_xref="GI:121636255"
                     /db_xref="GeneID:4699344"
                     /translation="MTSLIDYILSLFRSEDAARSFVAAPGRAMTSAGLIDIAPHQISS
                     VAANVVPGLNLGAGDPMSGLRQAVAARHGFAQDVANVGFAGDAGAGVASVITTDVGAG
                     LASGLGAGFLGQGGLALAASSGGFGGQVGLAAQVGLGFTAVIEAEVGAQVGAGLGIGT
                     GLGAQAGMGFGGGVGLGLGGQAGGVIGGSAAGAIGAGVGGRLGGNGQIGVAGQGAVGA
                     GVGAGVGGQAGIASQIGVSAGGGLGGVGNVSGLTGVSSNAVLASNASGQAGLIASEGA
                     ALNGAAMPHLSGPLAGVGVGGQAGAAGGAGLGFGAVGHPTPQPAALGAAGVVAKTEAA
                     AGVVGGVGGATAAGVGGAHGDILGHEGAALGSVDTVNAGVTPVEHGLVLPSGPLIHGG
                     TGGYGGMNPPVTDAPAPQVPARAQPMTTAAEHTPAVTQPQHTPVEPPVHDKPPSHSVF
                     DVGHEPPVTHTPPAPIELPSYGLFGLPGF"
     misc_feature    <441489..>441704
                     /gene="iniB"
                     /locus_tag="BCG_0380"
                     /note="EBNA-3A; Provisional; Region: PHA03379"
                     /db_xref="CDD:223066"
     gene            441765..443687
                     /gene="iniA"
                     /locus_tag="BCG_0381"
                     /db_xref="GeneID:4697078"
     CDS             441765..443687
                     /gene="iniA"
                     /locus_tag="BCG_0381"
                     /note="Differs from by 2aa, S88N, Q481H"
                     /codon_start=1
                     /transl_table=11
                     /product="isoniazid inductible gene protein iniA"
                     /protein_id="YP_976479.1"
                     /db_xref="GI:121636256"
                     /db_xref="GeneID:4697078"
                     /translation="MVPAGLCAYRDLRRKRARKWGDTVTQPDDPRRVGVIVELIDHTI
                     AIAKLNERGDLVQRLTRARQRITDPQVRVVIAGLLKQGKSQLLSSLLNLPAARVGDDE
                     ATVVITVVSYSAQPSARLVLAAGPDGTTAAVDIPVDDISTDVRRAPHAGGREVLRVEV
                     GAPSPLLRGGLAFIDTPGVGGLGQPHLSATLGLLPEADAVLVVSDTSQEFTEPEMWFV
                     RQAHQICPVGAVVATKTDLYPRWREIVNANAAHLQRARVPMPIIAVSSLLRSHAVTLN
                     DKELNEESNFPAIVKFLSEQVLSRATERVRAGVLGEIRSATEQLAVSLGSELSVVNDP
                     NLRDRLASDLERRKREAQQAVQQTALWQQVLGDGFNDLTADVDHDLRTRFRTVTEDAE
                     RQIDSCDPTAHWAEIGNDVENAIATAVGDNFVWAYQRSEALADDVARSFADAGLDSVL
                     SAELSPHVMGTDFGRLKALGRMESKPLRRGQKMIIGMRGSYGGVVMIGMLSSVVGLGL
                     FNPLSVGAGLILGRMAYKEDKQNRLLRVRSEAKANVRRFVDDISFVVSKQSRDRLKMI
                     QRLLRDHYREIAEEITRSLTESLQATIAAAQVAETERDNRIRELQRQLGILSQVNDNL
                     AGLEPTLTPRASLGRA"
     misc_feature    441765..443597
                     /gene="iniA"
                     /locus_tag="BCG_0381"
                     /note="Predicted GTPases (dynamin-related) [General
                     function prediction only]; Region: COG0699"
                     /db_xref="CDD:223771"
     misc_feature    442074..442400
                     /gene="iniA"
                     /locus_tag="BCG_0381"
                     /note="Rat sarcoma (Ras)-like superfamily of small
                     guanosine triphosphatases (GTPases); Region:
                     Ras_like_GTPase; cl17170"
                     /db_xref="CDD:266525"
     misc_feature    <442263..442649
                     /gene="iniA"
                     /locus_tag="BCG_0381"
                     /note="Rat sarcoma (Ras)-like superfamily of small
                     guanosine triphosphatases (GTPases); Region:
                     Ras_like_GTPase; cl17170"
                     /db_xref="CDD:266525"
     misc_feature    442287..442298
                     /gene="iniA"
                     /locus_tag="BCG_0381"
                     /note="G3 box; other site"
                     /db_xref="CDD:206648"
     misc_feature    order(442293..442298,442356..442361)
                     /gene="iniA"
                     /locus_tag="BCG_0381"
                     /note="Switch II region; other site"
                     /db_xref="CDD:206648"
     misc_feature    order(442296..442298,442461..442466,442470..442472,
                     442557..442565)
                     /gene="iniA"
                     /locus_tag="BCG_0381"
                     /note="GTP/Mg2+ binding site [chemical binding]; other
                     site"
                     /db_xref="CDD:206648"
     misc_feature    442461..442472
                     /gene="iniA"
                     /locus_tag="BCG_0381"
                     /note="G4 box; other site"
                     /db_xref="CDD:206648"
     misc_feature    442557..442565
                     /gene="iniA"
                     /locus_tag="BCG_0381"
                     /note="G5 box; other site"
                     /db_xref="CDD:206648"
     gene            443684..445165
                     /gene="iniC"
                     /locus_tag="BCG_0382"
                     /db_xref="GeneID:4697077"
     CDS             443684..445165
                     /gene="iniC"
                     /locus_tag="BCG_0382"
                     /codon_start=1
                     /transl_table=11
                     /product="isoniazid inductible gene protein iniC"
                     /protein_id="YP_976480.1"
                     /db_xref="GI:121636257"
                     /db_xref="GeneID:4697077"
                     /translation="MSTSDRVRAILHATIQAYRGAPAYRQRGDVFCQLDRIGARLAEP
                     LRIALAGTLKAGKSTLVNALVGDDIAPTDATEATRIVTWFRHGPTPRVTANHRGGRRA
                     NVPITRRGGLSFDLRRINPAELIDLEVEWPAEELIDATIVDTPGTSSLACDASERTLR
                     LLVPADGVPRVDAVVFLLRTLNAADVALLKQIGGLVGGSVGALGIIGVASRADEIGAG
                     RIDAMLSANDVAKRFTRELNQMGICQAVVPVSGLLALTARTLRQTEFIALRKLAGAER
                     TELNRALLSVDRFVRRDSPLPVDAGIRAQLLERFGMFGIRMSIAVLAAGVTDSTGLAA
                     ELLERSGLVALRNVIDQQFAQRSDMLKAHTALVSLRRFVQTHPVPATPYVIADIDPLL
                     ADTHAFEELRMLSLLPSRATTLNDDEIASLRRIIGGSGTSAAARLGLDPANSREAPRA
                     ALAAAQHWRRRAAHPLNDPFTTRACRAAVRSAEAMVAEFSARR"
     misc_feature    443693..445162
                     /gene="iniC"
                     /locus_tag="BCG_0382"
                     /note="Predicted GTPases (dynamin-related) [General
                     function prediction only]; Region: COG0699"
                     /db_xref="CDD:223771"
     misc_feature    443816..444493
                     /gene="iniC"
                     /locus_tag="BCG_0382"
                     /note="ATP-binding cassette transporter nucleotide-binding
                     domain; Region: ABC_ATPase; cl21455"
                     /db_xref="CDD:271875"
     misc_feature    443834..443857
                     /gene="iniC"
                     /locus_tag="BCG_0382"
                     /note="G1 box; other site"
                     /db_xref="CDD:206648"
     misc_feature    order(443840..443860,444119..444121,444311..444316,
                     444320..444322,444431..444439)
                     /gene="iniC"
                     /locus_tag="BCG_0382"
                     /note="GTP/Mg2+ binding site [chemical binding]; other
                     site"
                     /db_xref="CDD:206648"
     misc_feature    443960..443962
                     /gene="iniC"
                     /locus_tag="BCG_0382"
                     /note="G2 box; other site"
                     /db_xref="CDD:206648"
     misc_feature    order(444002..444007,444017..444019)
                     /gene="iniC"
                     /locus_tag="BCG_0382"
                     /note="Switch I region; other site"
                     /db_xref="CDD:206648"
     misc_feature    444110..444121
                     /gene="iniC"
                     /locus_tag="BCG_0382"
                     /note="G3 box; other site"
                     /db_xref="CDD:206648"
     misc_feature    order(444116..444121,444197..444202)
                     /gene="iniC"
                     /locus_tag="BCG_0382"
                     /note="Switch II region; other site"
                     /db_xref="CDD:206648"
     misc_feature    444311..444322
                     /gene="iniC"
                     /locus_tag="BCG_0382"
                     /note="G4 box; other site"
                     /db_xref="CDD:206648"
     misc_feature    444431..444439
                     /gene="iniC"
                     /locus_tag="BCG_0382"
                     /note="G5 box; other site"
                     /db_xref="CDD:206648"
     gene            complement(445308..445868)
                     /gene="lpqJ"
                     /locus_tag="BCG_0383c"
                     /db_xref="GeneID:4697432"
     CDS             complement(445308..445868)
                     /gene="lpqJ"
                     /locus_tag="BCG_0383c"
                     /codon_start=1
                     /transl_table=11
                     /product="lipoprotein lpqJ"
                     /protein_id="YP_976481.1"
                     /db_xref="GI:121636258"
                     /db_xref="GeneID:4697432"
                     /translation="MRLSLIARGMAALLAATALVAGCNTTIDGRPVASPGSGPTEPTF
                     PTPRPTTAPPGTTAPTLPTTPVSPTAPAGAIPLPPDSNGYVFIETKSGMTRCQINRDS
                     VGCEAPFTNSPLRDGEHANGIHITAGGSVQWVLGNLGAIPTVSIDYRTYEAQGWTIDA
                     TTDGTRFTNNRTGHGMFVSIEKVDTF"
     gene            445977..446387
                     /locus_tag="BCG_0384"
                     /db_xref="GeneID:4698157"
     CDS             445977..446387
                     /locus_tag="BCG_0384"
                     /note="In Mycobacterium bovis, a frameshift due to a
                     single base deletion (a-*) leads to a shorter product with
                     a different NH2 part compared to its homolog in
                     Mycobacterium tuberculosis strain H37Rv in Mycobacterium
                     bovis BCG Pasteur"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_976482.1"
                     /db_xref="GI:121636259"
                     /db_xref="GeneID:4698157"
                     /translation="MLPSTVVGVLLAAGAGRWYGKPKVLVDGWLDTAVGALRDGGCND
                     VILVLGAVEVSAPAGVTAITAPDWQQGLSASVRAGLAQADREHADYAVLHVIDTPDVN
                     AKVVARVLGRALVSRSGLAGRGRIPAHSARRRGC"
     misc_feature    445977..>446315
                     /locus_tag="BCG_0384"
                     /note="Uncharacterized MobA-related protein [General
                     function prediction only]; Region: COG2068"
                     /db_xref="CDD:224979"
     misc_feature    order(446007..446009,446013..446015,446115..446117,
                     446259..446261,446265..446267)
                     /locus_tag="BCG_0384"
                     /note="active site"
                     /db_xref="CDD:132997"
     gene            complement(446429..447892)
                     /gene="ansP2"
                     /locus_tag="BCG_0385c"
                     /db_xref="GeneID:4695803"
     CDS             complement(446429..447892)
                     /gene="ansP2"
                     /locus_tag="BCG_0385c"
                     /standard_name="aroP2"
                     /codon_start=1
                     /transl_table=11
                     /product="l-asparagine permease ansP2"
                     /protein_id="YP_976483.1"
                     /db_xref="GI:121636260"
                     /db_xref="GeneID:4695803"
                     /translation="MPPLDITDERLTREDTGYHKGLHSRQLQMIALGGAIGTGLFLGA
                     GGRLASAGPGLFLVYGICGIFVFLILRALGELVLHRPSSGSFVSYAREFYGEKVAFVA
                     GWMYFLNWAMTGIVDTTAIAHYCHYWRAFQPIPQWTLALIALLVVLSMNLISVRLFGE
                     LEFWASLIKVIALVTFLIVGTVFLAGRYKIDGQETGVSLWSSHGGIVPTGLLPIVLVT
                     SGVVFAYAAIELVGIAAGETAEPAKIMPRAINSVVLRIACFYVGSTVLLALLLPYTAY
                     KEHVSPFVTFFSKIGIDAAGSVMNLVVLTAALSSLNAGLYSTGRILRSMAINGSGPRF
                     TAPMSKTGVPYGGILLTAGIGLLGIILNAIKPSQAFEIVLHIAATGVIAAWATIVACQ
                     LRLHRMANAGQLQRPKFRMPLSPFSGYLTLAFLAGVLILMYFDEQHGPWMIAATVIGV
                     PALIGGWYLVRNRVTAVAHHAIDHTKSVAVVHSADPI"
     misc_feature    complement(446474..447868)
                     /gene="ansP2"
                     /locus_tag="BCG_0385c"
                     /note="Gamma-aminobutyrate permease and related permeases
                     [Amino acid transport and metabolism]; Region: AnsP;
                     COG1113"
                     /db_xref="CDD:224038"
     gene            448231..449217
                     /locus_tag="BCG_0386"
                     /db_xref="GeneID:4697141"
     CDS             448231..449217
                     /locus_tag="BCG_0386"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_976484.1"
                     /db_xref="GI:121636261"
                     /db_xref="GeneID:4697141"
                     /translation="MPGARELTLRVERGALFRRRWAASAASSARAAIRRDPRRCALGT
                     RPRWVSFLVIVLVIMNVVTAHPKYPNDPLALVLIELRHPRTEPPVPSAISILKEELAR
                     WTPILEQEEVRQVNLETGEHTAHSQKKLVARDRRTAITFRPDAMTLEVTDYPGWEEFR
                     SIVHAMVTARQDVAPVDGCIRIGLRYINEIRASLAEPSGWAYWVAESLLGPGTQLADL
                     KLTTTAQRHVIQCEGPEPGDSLTLRYAGARGAVIQSTPFLQRLKEPPAEGDFFLIDID
                     SAWSDPCKGIPALDAHLVDEVAERLHTPIGPLFESLITSELRTKVLQQPGQE"
     misc_feature    448429..449190
                     /locus_tag="BCG_0386"
                     /note="TIGR04255 family protein; Region: sporadTIGR04255"
                     /db_xref="CDD:234524"
     gene            449220..449873
                     /locus_tag="BCG_0387"
                     /db_xref="GeneID:4695384"
     CDS             449220..449873
                     /locus_tag="BCG_0387"
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulatory protein"
                     /protein_id="YP_976485.1"
                     /db_xref="GI:121636262"
                     /db_xref="GeneID:4695384"
                     /translation="MTISFSSSNLRDDATSGNGDYRLDKLPETTPSTSVFDRADVTYR
                     QFTELHGQARDTRREAHVVELESKTGERARCAPMHALEQLADYGFAWRDIARVVGVSV
                     PAITKWRKGAGVTGENRLKIARLLALIDMLSDRFIGEPASWLEMPIQAGVGITRMDLL
                     ERGRYDLVLALASTHTGDGTVEYVLNETDKDWRETVVDNAFESYTAEDGVISIRPKR"
     gene            449876..450535
                     /locus_tag="BCG_0388"
                     /db_xref="GeneID:4695917"
     CDS             449876..450535
                     /locus_tag="BCG_0388"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_976486.1"
                     /db_xref="GI:121636263"
                     /db_xref="GeneID:4695917"
                     /translation="MPELETPDDPESIYLARLEDVGEHRPTFTGDIYRLGDGRMVMIL
                     QHPCALRHGVDLHPRLLVAPVRPDSLRSNWARAPFGTMPLPKLIDGQDHSADFINLEL
                     IDSPTLPTCERIAVLSQSGVNLVMQRWVYHSTRLAVPTHTYSDSTVGPFDEADLIEEW
                     VTDRVDDGADPQAAEHECASWLDERISGRTRRALLSDRQHASSIRREARSHRKSVKLA
                     D"
     gene            450762..452639
                     /gene="dnaK"
                     /locus_tag="BCG_0389"
                     /db_xref="GeneID:4697869"
     CDS             450762..452639
                     /gene="dnaK"
                     /locus_tag="BCG_0389"
                     /EC_number="3.6.1.-"
                     /standard_name="hsp70"
                     /note="heat shock protein 70; assists in folding of
                     nascent polypeptide chains; refolding of misfolded
                     proteins; utilizes ATPase activity to help fold;
                     co-chaperones are DnaJ and GrpE; multiple copies in some
                     bacteria"
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone DnaK"
                     /protein_id="YP_976487.1"
                     /db_xref="GI:121636264"
                     /db_xref="GeneID:4697869"
                     /translation="MARAVGIDLGTTNSVVSVLEGGDPVVVANSEGSRTTPSIVAFAR
                     NGEVLVGQPAKNQAVTNVDRTVRSVKRHMGSDWSIEIDGKKYTAPEISARILMKLKRD
                     AEAYLGEDITDAVITTPAYFNDAQRQATKDAGQIAGLNVLRIVNEPTAAALAYGLDKG
                     EKEQRILVFDLGGGTFDVSLLEIGEGVVEVRATSGDNHLGGDDWDQRVVDWLVDKFKG
                     TSGIDLTKDKMAMQRLREAAEKAKIELSSSQSTSINLPYITVDADKNPLFLDEQLTRA
                     EFQRITQDLLDRTRKPFQSVIADTGISVSEIDHVVLVGGSTRMPAVTDLVKELTGGKE
                     PNKGVNPDEVVAVGAALQAGVLKGEVKDVLLLDVTPLSLGIETKGGVMTRLIERNTTI
                     PTKRSETFTTADDNQPSVQIQVYQGEREIAAHNKLLGSFELTGIPPAPRGIPQIEVTF
                     DIDANGIVHVTAKDKGTGKENTIRIQEGSGLSKEDIDRMIKDAEAHAEEDRKRREEAD
                     VRNQAETLVYQTEKFVKEQREAEGGSKVPEDTLNKVDAAVAEAKAALGGSDISAIKSA
                     MEKLGQESQALGQAIYEAAQAASQATGAAHPGGEPGGAHPGSADDVVDAEVVDDGREA
                     K"
     misc_feature    450762..452561
                     /gene="dnaK"
                     /locus_tag="BCG_0389"
                     /note="molecular chaperone DnaK; Provisional; Region:
                     dnaK; PRK00290"
                     /db_xref="CDD:234715"
     misc_feature    450762..451829
                     /gene="dnaK"
                     /locus_tag="BCG_0389"
                     /note="Nucleotide-binding domain of human HSPA9 and
                     similar proteins; Region: HSPA9-Ssq1-like_NBD; cd10234"
                     /db_xref="CDD:212676"
     misc_feature    order(450789..450800,450969..450971,451200..451202,
                     451275..451280,451284..451286,451362..451364,
                     451476..451478,451485..451487,451497..451499,
                     451701..451709,451713..451715)
                     /gene="dnaK"
                     /locus_tag="BCG_0389"
                     /note="nucleotide binding site [chemical binding]; other
                     site"
                     /db_xref="CDD:212676"
     misc_feature    order(450843..450845,450852..450854,450906..450908,
                     450918..450920,450927..450932,450936..450941,
                     451074..451085,451446..451448,451455..451460,
                     451467..451469,451521..451523,451527..451532)
                     /gene="dnaK"
                     /locus_tag="BCG_0389"
                     /note="NEF interaction site [polypeptide binding]; other
                     site"
                     /db_xref="CDD:212676"
     misc_feature    order(451131..451136,451140..451145,451188..451193,
                     451197..451199,451323..451334)
                     /gene="dnaK"
                     /locus_tag="BCG_0389"
                     /note="SBD interface [polypeptide binding]; other site"
                     /db_xref="CDD:212676"
     gene            452636..453343
                     /gene="grpE"
                     /locus_tag="BCG_0390"
                     /db_xref="GeneID:4699017"
     CDS             452636..453343
                     /gene="grpE"
                     /locus_tag="BCG_0390"
                     /note="with DnaK and DnaJ acts in response to hyperosmotic
                     and heat shock by preventing the aggregation of
                     stress-denatured proteins; may act as a thermosensor"
                     /codon_start=1
                     /transl_table=11
                     /product="heat shock protein GrpE"
                     /protein_id="YP_976488.1"
                     /db_xref="GI:121636265"
                     /db_xref="GeneID:4699017"
                     /translation="MTDGNQKPDGNSGEQVTVTDKRRIDPETGEVRHVPPGDMPGGTA
                     AADAAHTEDKVAELTADLQRVQADFANYRKRALRDQQAAADRAKASVVSQLLGVLDDL
                     ERARKHGDLESGPLKSVADKLDSALTGLGLVAFGAEGEDFDPVLHEAVQHEGDGGQGS
                     KPVIGTVMRQGYQLGEQVLRHALVGVVDTVVVDAAELESVDDGTAVADTAENDQADQG
                     NSADTLGEQAESEPSGS"
     misc_feature    452801..453184
                     /gene="grpE"
                     /locus_tag="BCG_0390"
                     /note="nucleotide exchange factor GrpE; Region: GrpE;
                     cd00446"
                     /db_xref="CDD:271355"
     misc_feature    452801..452953
                     /gene="grpE"
                     /locus_tag="BCG_0390"
                     /note="2-helical coiled coil; other site"
                     /db_xref="CDD:271355"
     misc_feature    order(452807..452809,452816..452821,452828..452833,
                     452837..452842,452849..452857,452861..452863,
                     452870..452875,452882..452887,452894..452899,
                     452903..452908,452915..452923,452927..452941,
                     452945..452950,452978..452983,452987..452995,
                     453002..453004,453020..453025)
                     /gene="grpE"
                     /locus_tag="BCG_0390"
                     /note="dimer interface [polypeptide binding]; other site"
                     /db_xref="CDD:271355"
     misc_feature    order(452855..452857,452879..452881,452945..452947,
                     452954..452956,453059..453061,453065..453070,
                     453074..453088,453137..453139,453164..453166,
                     453176..453178,453182..453184)
                     /gene="grpE"
                     /locus_tag="BCG_0390"
                     /note="Hsp70 (ATPase domain) interactions [polypeptide
                     binding]; other site"
                     /db_xref="CDD:271355"
     misc_feature    452978..453025
                     /gene="grpE"
                     /locus_tag="BCG_0390"
                     /note="2-helical coiled coil; other site"
                     /db_xref="CDD:271355"
     gene            453379..454566
                     /gene="dnaJ1"
                     /locus_tag="BCG_0391"
                     /db_xref="GeneID:4697812"
     CDS             453379..454566
                     /gene="dnaJ1"
                     /locus_tag="BCG_0391"
                     /standard_name="dnaJ"
                     /note="chaperone Hsp40; co-chaperone with DnaK;
                     Participates actively in the response to hyperosmotic and
                     heat shock by preventing the aggregation of
                     stress-denatured proteins and by disaggregating proteins,
                     also in an autonomous, dnaK-independent fashion"
                     /codon_start=1
                     /transl_table=11
                     /product="chaperone protein DnaJ"
                     /protein_id="YP_976489.1"
                     /db_xref="GI:121636266"
                     /db_xref="GeneID:4697812"
                     /translation="MAQREWVEKDFYQELGVSSDASPEEIKRAYRKLARDLHPDANPG
                     NPAAGERFKAVSEAHNVLSDPAKRKEYDETRRLFAGGGFGGRRFDSGFGGGFGGFGVG
                     GDGAEFNLNDLFDAASRTGGTTIGDLFGGLFGRGGSARPSRPRRGNDLETETELDFVE
                     AAKGVAMPLRLTSPAPCTNCHGSGARPGTSPKVCPTCNGSGVINRNQGAFGFSEPCTD
                     CRGSGSIIEHPCEECKGTGVTTRTRTINVRIPPGVEDGQRIRLAGQGEAGLRGAPSGD
                     LYVAVHVRPDKIFGRDGDDLTVTVPVSFTELALGSTLSVPTLDGTVGVRVPKGTADGR
                     ILRVRGRGVPKRSGGSGDLLVTVKVAVPPNLAGAAQEALEAYAAAERSSGFNPRAGWA
                     GNR"
     misc_feature    453379..454557
                     /gene="dnaJ1"
                     /locus_tag="BCG_0391"
                     /note="chaperone protein DnaJ; Provisional; Region:
                     PRK14279"
                     /db_xref="CDD:237655"
     misc_feature    453406..453570
                     /gene="dnaJ1"
                     /locus_tag="BCG_0391"
                     /note="DnaJ domain or J-domain.  DnaJ/Hsp40 (heat shock
                     protein 40) proteins are highly conserved and play crucial
                     roles in protein translation, folding, unfolding,
                     translocation, and degradation. They act primarily by
                     stimulating the ATPase activity of Hsp70s; Region: DnaJ;
                     cd06257"
                     /db_xref="CDD:99751"
     misc_feature    order(453490..453498,453523..453525,453532..453537,
                     453544..453549)
                     /gene="dnaJ1"
                     /locus_tag="BCG_0391"
                     /note="HSP70 interaction site [polypeptide binding]; other
                     site"
                     /db_xref="CDD:99751"
     misc_feature    453907..454080
                     /gene="dnaJ1"
                     /locus_tag="BCG_0391"
                     /note="Zinc finger domain of DnaJ and HSP40; Region:
                     DnaJ_zf; cd10719"
                     /db_xref="CDD:199908"
     misc_feature    order(453907..453909,453916..453918,453958..453960,
                     453967..453969,454024..454026,454033..454035,
                     454066..454068,454075..454077)
                     /gene="dnaJ1"
                     /locus_tag="BCG_0391"
                     /note="Zn binding sites [ion binding]; other site"
                     /db_xref="CDD:199908"
     misc_feature    <454111..454473
                     /gene="dnaJ1"
                     /locus_tag="BCG_0391"
                     /note="C-terminal substrate binding domain of DnaJ and
                     HSP40; Region: DnaJ_C; cd10747"
                     /db_xref="CDD:199909"
     misc_feature    order(454288..454293,454300..454305,454363..454374,
                     454459..454473)
                     /gene="dnaJ1"
                     /locus_tag="BCG_0391"
                     /note="dimer interface [polypeptide binding]; other site"
                     /db_xref="CDD:199909"
     gene            454566..454946
                     /gene="hspR"
                     /locus_tag="BCG_0392"
                     /db_xref="GeneID:4699347"
     CDS             454566..454946
                     /gene="hspR"
                     /locus_tag="BCG_0392"
                     /codon_start=1
                     /transl_table=11
                     /product="heat shock protein transcriptional regulator
                     HspR"
                     /protein_id="YP_976490.1"
                     /db_xref="GI:121636267"
                     /db_xref="GeneID:4699347"
                     /translation="MAKNPKDGESRTFLISVAAELAGMHAQTLRTYDRLGLVSPRRTS
                     GGGRRYSLHDVELLRQVQHLSQDEGVNLAGIKRIIELTSQVEALQSRLQEMAEELAVL
                     RANQRREVAVVPKSTALVVWKPRR"
     misc_feature    454599..454892
                     /gene="hspR"
                     /locus_tag="BCG_0392"
                     /note="Helix-Turn-Helix DNA binding domain of HspR-like
                     transcription regulators; Region: HTH_HspR-like; cd01279"
                     /db_xref="CDD:133387"
     misc_feature    454602..>454889
                     /gene="hspR"
                     /locus_tag="BCG_0392"
                     /note="Predicted transcriptional regulators
                     [Transcription]; Region: SoxR; COG0789"
                     /db_xref="CDD:223860"
     misc_feature    order(454605..454613,454653..454655,454701..454709)
                     /gene="hspR"
                     /locus_tag="BCG_0392"
                     /note="DNA binding residues [nucleotide binding]"
                     /db_xref="CDD:133387"
     misc_feature    order(454743..454745,454752..454754,454767..454772,
                     454797..454799,454827..454829,454839..454841,
                     454857..454859,454869..454871,454878..454883)
                     /gene="hspR"
                     /locus_tag="BCG_0392"
                     /note="putative dimer interface [polypeptide binding];
                     other site"
                     /db_xref="CDD:133387"
     gene            complement(454969..465492)
                     /gene="PPE8"
                     /locus_tag="BCG_0393c"
                     /db_xref="GeneID:4696301"
     CDS             complement(454969..465492)
                     /gene="PPE8"
                     /locus_tag="BCG_0393c"
                     /note="In Mycobacterium tuberculosis strain H37Rv, PPE7
                     and PPE8 exist as 2 genes. In Mycobacterium bovis BCG
                     Pasteur, and Mycobacterium bovis, a 2 bp insertion (*-ta)
                     resulting in the absence of a stop codon between the 2
                     genes, leads to a single product, and an altered
                     C-terminus"
                     /codon_start=1
                     /transl_table=11
                     /product="PPE family protein"
                     /protein_id="YP_976491.1"
                     /db_xref="GI:121636268"
                     /db_xref="GeneID:4696301"
                     /translation="MSFAVLPPEINSARLYVGAGLAPMLDAAAAWDGLADELGSAAAS
                     FSAVTAGLAGSSWLGAASTAMTGAAAPYLGWLSAAAAQAQQAATQTRLAAAAFEAALA
                     ATVHPAIISANRALFVSLVVSNLLGQNAPAIAATEAAYEQMWAQDVAAMFGYHAGASA
                     AVSALTPFGQALPTVAGGGALVSAAAAQVTTRVFRNLGLANVGEGNVGNGNVGNFNLG
                     SANIGNGNIGSGNIGSSNIGFGNVGPGLTAALNNIGFGNTGSNNIGFGNTGSNNIGFG
                     NTGDGNRGIGLTGSGLLGFGGLNSGTGNIGLFNSGTGNVGIGNSGTGNWGIGNSGNSY
                     NTGFGNSGDANTGFFNSGIANTGVGNAGNYNTGSYNPGNSNTGGFNMGQYNTGYLNSG
                     NYNTGLANSGNVNTGAFITGNFNNGFLWRGDHQGLIFGSPGFFNSTSAPSSGFFNSGA
                     GSASGFLNSGANNSGFFNSSSGAIGNSGLANAGVLVSGVINSGNTVSGLFNMSLVAIT
                     TPALISGFFNTGSNMSGFFGGPPVFNLGLANRGVVNILGNANIGNYNILGSGNVGDFN
                     ILGSGNLGSQNILGSGNVGSFNIGSGNIGVFNVGSGSLGNYNIGSGNLGIYNIGFGNV
                     GDYNVGFGNAGDFNQGFANTGNNNIGFANTGNNNIGIGLSGDNQQGFNIASGWNSGTG
                     NSGLFNSGTNNVGIFNAGTGNVGIANSGTGNWGIGNPGTDNTGILNAGSYNTGILNAG
                     DFNTGFYNTGSYNTGGFNVGNTNTGNFNVGDTNTGSYNPGDTNTGFFNPGNVNTGAFD
                     TGDFNNGFLVAGDNQGQIAIDLSVTTPFIPINEQMVIDVHNVMTFGGNMITVTEASTV
                     FPQTFYLSGLFFFGPVNLSASTLTVPTITLTIGGPTVTVPISIVGALESRTITFLKID
                     PAPGIGNSTTNPSSGFFNSGTGGTSGFQNVGGGSSGVWNSGLSSAIGNSGFQNLGSLQ
                     SGWANLGNSVSGFFNTSTVNLSTPANVSGLNNIGTNLSGVFRGPTGTIFNAGLANLGQ
                     LNIGSANLGDFNLGSGNVGSFNVFSGNQGSYNIGPANLGNYNIGFANLGNYNIGFGNA
                     GDFNQGFANTGNNNIGFANTGNNNIGIGLSGDNQQGFNFAGGWNSGTANIGLFNSGTN
                     NVGIGNSGTGNWGIGNSGSGNTGIGNTGSTNTGFFNTGIVNTGVANAGSYNTGWYNTG
                     DTNTGIANLGDFNTGFYNTGNFSTGFANQGDIATGAFITGDMGNGAFWRGDQQGLFSA
                     GYRVHVPEIPAHVTVEVPVNIPITASFTNTVYSGITLEQINFGFTIDIAGIPLLAGAI
                     SKAVLPPITGTGPAITVNIGDPGGSTAIRIPATASVGPFDVTFVNIAATTGFFNATTD
                     PSSGFFNGGPGTVSGIANIGANISGFQNVANSATSGFNNYGSLQSGLANLGDTVSGVF
                     NTGIGAPANVSGMFNIGSNLAGFFHDQATGMSMFNLGLGNIGQFNVGFSNVGDSNAGL
                     ANIGSFNLGSGNLGSFNVFGGNQGSYNIGPANLGNYNIGLGNLGSYNFGFGNAGDFNL
                     GFANTGNNNIGFANTGNNNIGIGLSGDNQQGFNFAGGWNSGSGNSGLFNSGTNNIGLF
                     NSGTGNIGIGNSGTGNWGIANTGDTNTGIFNTGDVNTGLLNAGNVNTGIFNTGHYNTG
                     SFNAGSFNTAGFNPGSYNTGYLNTGSYNTGLANSGDVNTGGFITGNYSNGFWWRGDYQ
                     GLAGISQTITVPDTAVPVKLHVPIFLDIPVTGTLGTFTVHGFRFPEITGDIFLIGIPF
                     NAATLDAFSFPNISIVLPNIGINLGSGPDPLIDIAGTGGLLPIKIPLIDIPAAPGFGN
                     STTTPSSGFFNAGTGTVSGVGNVGSNSSGFFNLTSGSSGISGVQNFGELISGGFNFGN
                     TVSGLVNASTLGLSMPANLSGGGNVGATVAGFVNNTQILNLGFGNVGSGNVGHGNIGD
                     SNVGLGNLGNANVGHGNIGSFNVFSGNRGSYNIGPANLGNYNIGLGNLGSYNFGFGNA
                     GDFNLGFANSGSNNIGFANTGNNNIGIGLSGHNQQGFGSWNSGTANTGLFNSGTNNIG
                     LFNSGTGNIGIGNSGIGNTGIGNPGVGNTGLGNSGTGNWGLWNPGTGNMGVANVGTYN
                     TGGYNVGSTNTGIANVGIANTGSYNTGSTNTGSFNDGDFNTGFYNTGDYNTGFYNTGD
                     VNTGAFIGGNFSNGAFWQSDHQGQWGAHYAITVPQIPLLNFSLNIPVNIPIHLDFGTL
                     AVNGFQIPAITLRALGVTHFSVGPIIVPRIAGTLPVIDINIGDPGGSSSIPITITSGA
                     GPVVIPLLDIPPAPGFGNSTTGPSSGFFNSGTGSSSGFGNVGANNSGFWNTAFAGIGN
                     SGLQNFGSLQSGWANLGNTVSGFYNTSAADFATPANLSGLSNVGADLTGVLRGPNGST
                     FNAGLANLGQFNVGSANLGSANLGSANLGNSNVGFGNIGNANIGGANIGDFNVGIANT
                     GPGLTAAVNNIGIGNTGNYNIGVGNTGNYNIGFGNTGNNNIGIGLSGDNQIGFGPLNA
                     GIANMGLFNLGDNNFGMANAGNFNQGIANTGNNNIGLFNTGNNNVGIGLTGDGLSGFS
                     SLNSGAGNTGFFNSGTANTGLFNSGTGNTGLFNSGTGNVGIGNMGTGGFGVGLSGDSQ
                     VGIGGTNSGSFNIGLFNSGTGNVGIGNSGTGNVGIGNTGTGNTGIGNSGNYNTGLLNA
                     GLVNTGIANPGNHNTGLFNIGTFNTGIANPGHYNTGSYNTGSYNTGMANAGDYGTGAF
                     ITGSMNNGLLWRADRQGLLAANYTITIERPAAFLNVDIPVNIPITGDITNVSIPAITF
                     PRIDASGSVDIGILSGTVLAPVGPITLHGGDASAPLDTPIEIDFGPSPAINLNIGKPD
                     GSTVINIVGGAGAGPISIPIIDLRPAPGFFNATTGPSSGFLNWGAGSASGLLNFGNNS
                     GLYNFATSSMGNSGFQNYGSLQSGWANLGNSISGIYNTGLGAPANVSGLLNIGTNLAG
                     WLQNGPTETTFSVGLANLGFWNLGSANIGNYNLGSANIGVYNLGSANIGDFNLGSANI
                     GDFNLGSANIGSSNIGFGNVGPGLTAAIGNIGFGNTGNGNIGIGNTGTGNIGFGNTGN
                     GNIGIGLTGDTMTGFGGWNSGTGNIGLFNSGTGNIGFGNSGTGNWGIGNSGDYNTGIG
                     NTGSTNSGFFNTGLVNTGIGNSGDYNTGLFNAGNTNTGSFNPGDYNTGGFNPGNYNTG
                     YFNPGNSNTGFANSGDVNTGAFNSGNYSNGFFWRGDYQGLGGFAYQSAVSEIPWSYDI
                     GSNIEIPIEGDINAITQDAFTIDEFEIPIKLRVSVCVIYIPFKGCVKHVSVTIPITTE
                     HLGPYEIDASTINPDQPIDTAFTQTLDFAGSGTVGAFPFGFGWQQSPGFFNSTTTPSS
                     GFFNSGAGGASGFLNDAAAAVSGLGNVFTETSGFFNAGGVGNSGFQNFGNLLSGWANL
                     GNTVSGFYNTSMLDLATQALISGFGNHGARLSGILNNGSGP"
     misc_feature    complement(464050..465492)
                     /gene="PPE8"
                     /locus_tag="BCG_0393c"
                     /note="PPE-repeat proteins [Cell motility and secretion];
                     Region: COG5651"
                     /db_xref="CDD:227938"
     misc_feature    complement(465004..465480)
                     /gene="PPE8"
                     /locus_tag="BCG_0393c"
                     /note="PPE family; Region: PPE; pfam00823"
                     /db_xref="CDD:250158"
     misc_feature    complement(464374..464490)
                     /gene="PPE8"
                     /locus_tag="BCG_0393c"
                     /note="Pentapeptide repeats (8 copies); Region:
                     Pentapeptide_2; pfam01469"
                     /db_xref="CDD:250641"
     misc_feature    complement(463060..>464157)
                     /gene="PPE8"
                     /locus_tag="BCG_0393c"
                     /note="PPE-repeat proteins [Cell motility and secretion];
                     Region: COG5651"
                     /db_xref="CDD:227938"
     misc_feature    complement(463630..463749)
                     /gene="PPE8"
                     /locus_tag="BCG_0393c"
                     /note="Pentapeptide repeats (8 copies); Region:
                     Pentapeptide_2; pfam01469"
                     /db_xref="CDD:250641"
     misc_feature    complement(463540..463659)
                     /gene="PPE8"
                     /locus_tag="BCG_0393c"
                     /note="Pentapeptide repeats (8 copies); Region:
                     Pentapeptide_2; pfam01469"
                     /db_xref="CDD:250641"
     misc_feature    complement(463333..463449)
                     /gene="PPE8"
                     /locus_tag="BCG_0393c"
                     /note="Pentapeptide repeats (8 copies); Region:
                     Pentapeptide_2; pfam01469"
                     /db_xref="CDD:250641"
     misc_feature    complement(463210..463326)
                     /gene="PPE8"
                     /locus_tag="BCG_0393c"
                     /note="Pentapeptide repeats (8 copies); Region:
                     Pentapeptide_2; pfam01469"
                     /db_xref="CDD:250641"
     misc_feature    complement(463150..463266)
                     /gene="PPE8"
                     /locus_tag="BCG_0393c"
                     /note="Pentapeptide repeats (8 copies); Region:
                     Pentapeptide_2; pfam01469"
                     /db_xref="CDD:250641"
     misc_feature    complement(463060..463179)
                     /gene="PPE8"
                     /locus_tag="BCG_0393c"
                     /note="Pentapeptide repeats (8 copies); Region:
                     Pentapeptide_2; pfam01469"
                     /db_xref="CDD:250641"
     misc_feature    complement(461728..>462660)
                     /gene="PPE8"
                     /locus_tag="BCG_0393c"
                     /note="PPE-repeat proteins [Cell motility and secretion];
                     Region: COG5651"
                     /db_xref="CDD:227938"
     misc_feature    complement(462301..462417)
                     /gene="PPE8"
                     /locus_tag="BCG_0393c"
                     /note="Pentapeptide repeats (8 copies); Region:
                     Pentapeptide_2; pfam01469"
                     /db_xref="CDD:250641"
     misc_feature    complement(462178..462297)
                     /gene="PPE8"
                     /locus_tag="BCG_0393c"
                     /note="Pentapeptide repeats (8 copies); Region:
                     Pentapeptide_2; pfam01469"
                     /db_xref="CDD:250641"
     misc_feature    complement(461968..462087)
                     /gene="PPE8"
                     /locus_tag="BCG_0393c"
                     /note="Pentapeptide repeats (8 copies); Region:
                     Pentapeptide_2; pfam01469"
                     /db_xref="CDD:250641"
     misc_feature    complement(461878..461997)
                     /gene="PPE8"
                     /locus_tag="BCG_0393c"
                     /note="Pentapeptide repeats (8 copies); Region:
                     Pentapeptide_2; pfam01469"
                     /db_xref="CDD:250641"
     misc_feature    complement(461818..461934)
                     /gene="PPE8"
                     /locus_tag="BCG_0393c"
                     /note="Pentapeptide repeats (8 copies); Region:
                     Pentapeptide_2; pfam01469"
                     /db_xref="CDD:250641"
     misc_feature    complement(460321..>461082)
                     /gene="PPE8"
                     /locus_tag="BCG_0393c"
                     /note="PPE-repeat proteins [Cell motility and secretion];
                     Region: COG5651"
                     /db_xref="CDD:227938"
     misc_feature    complement(460924..461037)
                     /gene="PPE8"
                     /locus_tag="BCG_0393c"
                     /note="Pentapeptide repeats (8 copies); Region:
                     Pentapeptide_2; pfam01469"
                     /db_xref="CDD:250641"
     misc_feature    complement(460774..460890)
                     /gene="PPE8"
                     /locus_tag="BCG_0393c"
                     /note="Pentapeptide repeats (8 copies); Region:
                     Pentapeptide_2; pfam01469"
                     /db_xref="CDD:250641"
     misc_feature    complement(460591..460710)
                     /gene="PPE8"
                     /locus_tag="BCG_0393c"
                     /note="Pentapeptide repeats (8 copies); Region:
                     Pentapeptide_2; pfam01469"
                     /db_xref="CDD:250641"
     misc_feature    complement(460471..460590)
                     /gene="PPE8"
                     /locus_tag="BCG_0393c"
                     /note="Pentapeptide repeats (8 copies); Region:
                     Pentapeptide_2; pfam01469"
                     /db_xref="CDD:250641"
     misc_feature    complement(460381..460497)
                     /gene="PPE8"
                     /locus_tag="BCG_0393c"
                     /note="Pentapeptide repeats (8 copies); Region:
                     Pentapeptide_2; pfam01469"
                     /db_xref="CDD:250641"
     misc_feature    complement(458863..>459939)
                     /gene="PPE8"
                     /locus_tag="BCG_0393c"
                     /note="PPE-repeat proteins [Cell motility and secretion];
                     Region: COG5651"
                     /db_xref="CDD:227938"
     misc_feature    complement(459559..459675)
                     /gene="PPE8"
                     /locus_tag="BCG_0393c"
                     /note="Pentapeptide repeats (8 copies); Region:
                     Pentapeptide_2; pfam01469"
                     /db_xref="CDD:250641"
     misc_feature    complement(459454..459573)
                     /gene="PPE8"
                     /locus_tag="BCG_0393c"
                     /note="Pentapeptide repeats (8 copies); Region:
                     Pentapeptide_2; pfam01469"
                     /db_xref="CDD:250641"
     misc_feature    complement(459367..459483)
                     /gene="PPE8"
                     /locus_tag="BCG_0393c"
                     /note="Pentapeptide repeats (8 copies); Region:
                     Pentapeptide_2; pfam01469"
                     /db_xref="CDD:250641"
     misc_feature    complement(459196..459312)
                     /gene="PPE8"
                     /locus_tag="BCG_0393c"
                     /note="Pentapeptide repeats (8 copies); Region:
                     Pentapeptide_2; pfam01469"
                     /db_xref="CDD:250641"
     misc_feature    complement(457597..459210)
                     /gene="PPE8"
                     /locus_tag="BCG_0393c"
                     /note="PPE-repeat proteins [Cell motility and secretion];
                     Region: COG5651"
                     /db_xref="CDD:227938"
     misc_feature    complement(459073..459192)
                     /gene="PPE8"
                     /locus_tag="BCG_0393c"
                     /note="Pentapeptide repeats (8 copies); Region:
                     Pentapeptide_2; pfam01469"
                     /db_xref="CDD:250641"
     misc_feature    complement(458923..459042)
                     /gene="PPE8"
                     /locus_tag="BCG_0393c"
                     /note="Pentapeptide repeats (8 copies); Region:
                     Pentapeptide_2; pfam01469"
                     /db_xref="CDD:250641"
     misc_feature    complement(458077..458193)
                     /gene="PPE8"
                     /locus_tag="BCG_0393c"
                     /note="Pentapeptide repeats (8 copies); Region:
                     Pentapeptide_2; pfam01469"
                     /db_xref="CDD:250641"
     misc_feature    complement(457909..458025)
                     /gene="PPE8"
                     /locus_tag="BCG_0393c"
                     /note="Pentapeptide repeats (8 copies); Region:
                     Pentapeptide_2; pfam01469"
                     /db_xref="CDD:250641"
     misc_feature    complement(457570..457686)
                     /gene="PPE8"
                     /locus_tag="BCG_0393c"
                     /note="Pentapeptide repeats (8 copies); Region:
                     Pentapeptide_2; pfam01469"
                     /db_xref="CDD:250641"
     misc_feature    complement(457381..457497)
                     /gene="PPE8"
                     /locus_tag="BCG_0393c"
                     /note="Pentapeptide repeats (8 copies); Region:
                     Pentapeptide_2; pfam01469"
                     /db_xref="CDD:250641"
     misc_feature    complement(457294..457410)
                     /gene="PPE8"
                     /locus_tag="BCG_0393c"
                     /note="Pentapeptide repeats (8 copies); Region:
                     Pentapeptide_2; pfam01469"
                     /db_xref="CDD:250641"
     misc_feature    complement(457201..457317)
                     /gene="PPE8"
                     /locus_tag="BCG_0393c"
                     /note="Pentapeptide repeats (8 copies); Region:
                     Pentapeptide_2; pfam01469"
                     /db_xref="CDD:250641"
     misc_feature    complement(455683..>456720)
                     /gene="PPE8"
                     /locus_tag="BCG_0393c"
                     /note="PPE-repeat proteins [Cell motility and secretion];
                     Region: COG5651"
                     /db_xref="CDD:227938"
     misc_feature    complement(456292..456411)
                     /gene="PPE8"
                     /locus_tag="BCG_0393c"
                     /note="Pentapeptide repeats (8 copies); Region:
                     Pentapeptide_2; pfam01469"
                     /db_xref="CDD:250641"
     misc_feature    complement(456109..456228)
                     /gene="PPE8"
                     /locus_tag="BCG_0393c"
                     /note="Pentapeptide repeats (8 copies); Region:
                     Pentapeptide_2; pfam01469"
                     /db_xref="CDD:250641"
     misc_feature    complement(455953..456072)
                     /gene="PPE8"
                     /locus_tag="BCG_0393c"
                     /note="Pentapeptide repeats (8 copies); Region:
                     Pentapeptide_2; pfam01469"
                     /db_xref="CDD:250641"
     misc_feature    complement(455863..455979)
                     /gene="PPE8"
                     /locus_tag="BCG_0393c"
                     /note="Pentapeptide repeats (8 copies); Region:
                     Pentapeptide_2; pfam01469"
                     /db_xref="CDD:250641"
     misc_feature    complement(455803..455919)
                     /gene="PPE8"
                     /locus_tag="BCG_0393c"
                     /note="Pentapeptide repeats (8 copies); Region:
                     Pentapeptide_2; pfam01469"
                     /db_xref="CDD:250641"
     misc_feature    complement(455713..455829)
                     /gene="PPE8"
                     /locus_tag="BCG_0393c"
                     /note="Pentapeptide repeats (8 copies); Region:
                     Pentapeptide_2; pfam01469"
                     /db_xref="CDD:250641"
     gene            complement(465643..466287)
                     /locus_tag="BCG_0394c"
                     /db_xref="GeneID:4696417"
     CDS             complement(465643..466287)
                     /locus_tag="BCG_0394c"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_976492.1"
                     /db_xref="GI:121636269"
                     /db_xref="GeneID:4696417"
                     /translation="MTDASVHPDELDPEYHHHGGFPEYGPASPGAGFGQFVATMRRLQ
                     DLAVAADPGDAVWDEAAERAAALVELLSPFEADEGKAPAGRTPGLPGMGSLLLPPWTV
                     TRYGTDGVEMRGSFSRFHVGGNSAVHGGVLPLLFDHMFGMISHAAGRPISRTAFLHVD
                     YRRITPIDVPLIVRGRVTNTEGRKAFVCAELFDSDETLLAEGNGLMVRLLPGQP"
     misc_feature    complement(465664..465999)
                     /locus_tag="BCG_0394c"
                     /note="PaaI_thioesterase is a tetrameric acyl-CoA
                     thioesterase with a hot dog fold and one of several
                     proteins responsible for phenylacetic acid (PA)
                     degradation in bacteria.  Although orthologs of PaaI exist
                     in archaea and eukaryotes, their function has not...;
                     Region: PaaI_thioesterase; cd03443"
                     /db_xref="CDD:239527"
     misc_feature    complement(order(465796..465807,465826..465828,
                     465907..465909))
                     /locus_tag="BCG_0394c"
                     /note="CoenzymeA binding site [chemical binding]; other
                     site"
                     /db_xref="CDD:239527"
     misc_feature    complement(order(465805..465807,465811..465825,
                     465889..465891,465898..465900,465904..465906))
                     /locus_tag="BCG_0394c"
                     /note="subunit interaction site [polypeptide binding];
                     other site"
                     /db_xref="CDD:239527"
     misc_feature    complement(order(465826..465828,465862..465867,
                     465874..465879,465901..465903))
                     /locus_tag="BCG_0394c"
                     /note="PHB binding site; other site"
                     /db_xref="CDD:239527"
     gene            complement(466284..467582)
                     /gene="purA"
                     /locus_tag="BCG_0395c"
                     /db_xref="GeneID:4696674"
     CDS             complement(466284..467582)
                     /gene="purA"
                     /locus_tag="BCG_0395c"
                     /EC_number="6.3.4.4"
                     /note="catalyzes the formation of
                     N6-(1,2,-dicarboxyethyl)-AMP from L-aspartate, inosine
                     monophosphate and GTP in AMP biosynthesis"
                     /codon_start=1
                     /transl_table=11
                     /product="adenylosuccinate synthetase"
                     /protein_id="YP_976493.1"
                     /db_xref="GI:121636270"
                     /db_xref="GeneID:4696674"
                     /translation="MPAIVLIGAQWGDEGKGKATDLLGGRVQWVVRYQGGNNAGHTVV
                     LPTGENFALHLIPSGVLTPGVTNVIGNGVVIDPGVLLNELRGLQDRGVDTAKLLISAD
                     AHLLMPYHIAIDKVTERYMGSKKIGTTGRGIGPCYQDKIARIGIRVADVLDPEQLTHK
                     VEAACEFKNQVLVKIYNRKALDPAQVVDALLEQAEGFKHRIADTRLLLNAALEAGETV
                     LLEGSQGTLLDVDHGTYPYVTSSNPTAGGAAVGSGIGPTRIGTVLGILKAYTTRVGSG
                     PFPTELFDEHGEYLSKTGREFGVTTGRRRRCGWFDAVIARYAARVNGITDYFLTKLDV
                     LSSLESVPVCVGYEIDGRRTRDMPMTQRDLCRAKPVYEELPGWWEDISGAREFDDLPA
                     KARDYVLRLEQLAGAPVSCIGVGPGREQTIVRRDVLQDRP"
     misc_feature    complement(466335..467576)
                     /gene="purA"
                     /locus_tag="BCG_0395c"
                     /note="Adenylosuccinate synthetase (AdSS) catalyzes the
                     first step in the de novo biosynthesis of AMP. IMP and
                     L-aspartate are conjugated in a two-step reaction
                     accompanied by the hydrolysis of GTP to GDP in the
                     presence of Mg2+. In the first step, the...; Region: AdSS;
                     cd03108"
                     /db_xref="CDD:239382"
     misc_feature    complement(order(466335..466340,466584..466586,
                     466590..466592,467451..467453,467457..467465,
                     467532..467540,467544..467546))
                     /gene="purA"
                     /locus_tag="BCG_0395c"
                     /note="GDP-binding site [chemical binding]; other site"
                     /db_xref="CDD:239382"
     misc_feature    complement(order(467460..467462,467529..467531,
                     467538..467540))
                     /gene="purA"
                     /locus_tag="BCG_0395c"
                     /note="ACT binding site; other site"
                     /db_xref="CDD:239382"
     misc_feature    complement(order(466866..466868,466911..466913,
                     467196..467198,467205..467207,467469..467471))
                     /gene="purA"
                     /locus_tag="BCG_0395c"
                     /note="IMP binding site; other site"
                     /db_xref="CDD:239382"
     gene            467673..468320
                     /locus_tag="BCG_0396"
                     /db_xref="GeneID:4699225"
     CDS             467673..468320
                     /locus_tag="BCG_0396"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_976494.1"
                     /db_xref="GI:121636271"
                     /db_xref="GeneID:4699225"
                     /translation="MYTAENAPGVAVLLSGDADVPGPLTGLPTHQDNLDTVIGRYSRL
                     IVVGADADLGAVLTRLLRTDRLDVEVGYVPRRRSPATRAYRLPAGRRAARRARCGVAR
                     RVPLIRDETGSVIVGRAQWLPAEEQALIHGEAVVDDTVLFDGDVAGVCIEPTLTLPGL
                     RAAVDGAGKWRRWIGGRAAQLGTTGAAVLRDGVAAPRPVRRSTFYRNVEGWLLVR"
     gene            468331..469110
                     /locus_tag="BCG_0397"
                     /db_xref="GeneID:4697373"
     CDS             468331..469110
                     /locus_tag="BCG_0397"
                     /note="Differs from Rv0359 by 1aa, T252A"
                     /codon_start=1
                     /transl_table=11
                     /product="integral membrane protein"
                     /protein_id="YP_976495.1"
                     /db_xref="GI:121636272"
                     /db_xref="GeneID:4697373"
                     /translation="MSETGQRESVRPSPIFLGLLGLTAVGGALAWLAGETVQPLAYAG
                     VFVMVIAGWLVSLCLHEFGHAFTAWRFGDHDVAVRGYLTLDPRRYSHPMLSLGLPMLF
                     IALGGIGLPGAAVYVHTWFMTTARRTLVSLAGPTVNLALAMLLLAATRLLFDPIHAVL
                     WAGVAFLAFLQLTALVLNLLPIPGLDGYAALEPHLRPETQRALAPAKQFALVFLLVLF
                     LAPTLNGWFFGVVYWLFDLSGVSHRLAAAGSVLTRFWSIWF"
     misc_feature    468466..468954
                     /locus_tag="BCG_0397"
                     /note="Uncharacterized homologs of Site-2 protease (S2P),
                     zinc metalloproteases (MEROPS family M50) which cleave
                     transmembrane domains of substrate proteins, regulating
                     intramembrane proteolysis (RIP) of diverse signal
                     transduction mechanisms. Members of the...; Region:
                     S2P-M50_like_1; cd06158"
                     /db_xref="CDD:100079"
     misc_feature    468472..469002
                     /locus_tag="BCG_0397"
                     /note="Peptidase family M50; Region: Peptidase_M50;
                     pfam02163"
                     /db_xref="CDD:251129"
     misc_feature    order(468508..468513,468520..468522,468862..468864,
                     468886..468888)
                     /locus_tag="BCG_0397"
                     /note="active site"
                     /db_xref="CDD:100079"
     misc_feature    468862..468873
                     /locus_tag="BCG_0397"
                     /note="putative substrate binding region [chemical
                     binding]; other site"
                     /db_xref="CDD:100079"
     gene            complement(469115..469552)
                     /locus_tag="BCG_0398c"
                     /db_xref="GeneID:4696939"
     CDS             complement(469115..469552)
                     /locus_tag="BCG_0398c"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_976496.1"
                     /db_xref="GI:121636273"
                     /db_xref="GeneID:4696939"
                     /translation="MTKRTITPMTSMGDLLGPEPILLPGDSDAEAELLANESPSIVAA
                     AHPSASVAWAVLAEGALADDKTVTAYAYARTGYHRGLDQLRRHGWKGFGPVPYSHQPN
                     RGFLRCVAALARAAAAIGETDEYGRCLDLLDDCDPAARPALGL"
     misc_feature    complement(469124..469510)
                     /locus_tag="BCG_0398c"
                     /note="Protein of unknown function (DUF3151); Region:
                     DUF3151; pfam11349"
                     /db_xref="CDD:256426"
     gene            469635..470462
                     /locus_tag="BCG_0399"
                     /db_xref="GeneID:4696308"
     CDS             469635..470462
                     /locus_tag="BCG_0399"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_976497.1"
                     /db_xref="GI:121636274"
                     /db_xref="GeneID:4696308"
                     /translation="MSNAPEPDRSAGESGSEPAGERSADPGEERTESYPLVPHDAETE
                     TVVITTSDNDAAVTQPEAQRERRFTAPGFDAKETQVIVTAHEAATEVFQTNQAPTTPP
                     RMPTGMPPKTAVPQSIPPRTEATSVRQRTWGWALAVVVIVLALAAIAILGTVLLTRGK
                     HSKMSQEDQVRQAIQSLDIAIQTGDLTALRSLTCGSTRDGYVDYDERDWAETYRRVSA
                     AKQYPVIASIDQVVVNGAHAEANVTTFMAFDPQVRSTRSLDLQFRDDQWKICQSSSN"
     misc_feature    469914..>470111
                     /locus_tag="BCG_0399"
                     /note="Glycosyltransferase family A (GT-A) includes
                     diverse families of glycosyl transferases with a common
                     GT-A type structural fold; Region: Glyco_tranf_GTA_type;
                     cl11394"
                     /db_xref="CDD:271710"
     gene            470684..472066
                     /gene="mgtE"
                     /locus_tag="BCG_0400"
                     /db_xref="GeneID:4695690"
     CDS             470684..472066
                     /gene="mgtE"
                     /locus_tag="BCG_0400"
                     /note="Differs from Rv0362 by 1aa, V292A"
                     /codon_start=1
                     /transl_table=11
                     /product="Mg2+ transport transmembrane protein mgtE"
                     /protein_id="YP_976498.1"
                     /db_xref="GI:121636275"
                     /db_xref="GeneID:4695690"
                     /translation="MSIRPAENSTLDIRHVIGIGTPKAVDLWLDVVTELPDRARELGS
                     LSKAELGKLGPLLDGTNAVELFESIDDKLAAEALHAMDPSLAATFLEALDSDHAANIL
                     REFKEPKREALLTLLPLERAMVLRGLLSWPEDCAAAHMVPETLTVRPNMTVSQAVASV
                     RERASGLRSDARTTAYVYVTDADSHLLGVIAFRALVLANPEQRVRELMGDDLIVVSPL
                     TDKELAAQTIMGHNLMAVPVVDADNRLLGIIAEDEAIDIAEEEATEDAERQGGSAPLE
                     VPYLRASPWLLWRKRVVWLLVLFAAEAYTGSVLRAFSDEMEAVIALAFFIPLLIGTGG
                     NTGTQIATTLVRAMATGQVRFRDVPAVLAKELSTGVLVGLTMAAAAVVRAWTLGVGPQ
                     VTLTVALTVAAIVVWSSLVAAVLPPLLKKLRIDPAIVSGPMIATIVDGTGLLIYFLVA
                     HLTLTELHGL"
     misc_feature    470696..472057
                     /gene="mgtE"
                     /locus_tag="BCG_0400"
                     /note="Mg/Co/Ni transporter MgtE (contains CBS domain)
                     [Inorganic ion transport and metabolism]; Region: MgtE;
                     COG2239"
                     /db_xref="CDD:225148"
     misc_feature    470792..471085
                     /gene="mgtE"
                     /locus_tag="BCG_0400"
                     /note="MgtE intracellular N domain; Region: MgtE_N;
                     pfam03448"
                     /db_xref="CDD:146204"
     misc_feature    471119..471454
                     /gene="mgtE"
                     /locus_tag="BCG_0400"
                     /note="This cd contains two tandem repeats of the
                     cystathionine beta-synthase (CBS pair) domain in the
                     magnesium transporter, MgtE.  MgtE and its homologs are
                     found in eubacteria, archaebacteria, and eukaryota.
                     Members of this family transport Mg2+ or other...; Region:
                     CBS_pair_Mg_transporter; cd04606"
                     /db_xref="CDD:239979"
     misc_feature    471656..472033
                     /gene="mgtE"
                     /locus_tag="BCG_0400"
                     /note="Divalent cation transporter; Region: MgtE;
                     pfam01769"
                     /db_xref="CDD:110745"
     gene            complement(472078..473112)
                     /gene="fba"
                     /locus_tag="BCG_0401c"
                     /db_xref="GeneID:4699000"
     CDS             complement(472078..473112)
                     /gene="fba"
                     /locus_tag="BCG_0401c"
                     /EC_number="4.1.2.13"
                     /standard_name="fda"
                     /note="catalyzes the formation of glycerone phosphate and
                     glyceraldehyde 3-phosphate from fructose 1,6,
                     bisphosphate"
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-bisphosphate aldolase"
                     /protein_id="YP_976499.1"
                     /db_xref="GI:121636276"
                     /db_xref="GeneID:4699000"
                     /translation="MPIATPEVYAEMLGQAKQNSYAFPAINCTSSETVNAAIKGFADA
                     GSDGIIQFSTGGAEFGSGLGVKDMVTGAVALAEFTHVIAAKYPVNVALHTDHCPKDKL
                     DSYVRPLLAISAQRVSKGGNPLFQSHMWDGSAVPIDENLAIAQELLKAAAAAKIILEI
                     EIGVVGGEEDGVANEINEKLYTSPEDFEKTIEALGAGEHGKYLLAATFGNVHGVYKPG
                     NVKLRPDILAQGQQVAAAKLGLPADAKPFDFVFHGGSGSLKSEIEEALRYGVVKMNVD
                     TDTQYAFTRPIAGHMFTNYDGVLKVDGEVGVKKVYDPRSYLKKAEASMSQRVVQACND
                     LHCAGKSLTH"
     misc_feature    complement(472087..473112)
                     /gene="fba"
                     /locus_tag="BCG_0401c"
                     /note="fructose-bisphosphate aldolase; Provisional;
                     Region: PRK09197"
                     /db_xref="CDD:236406"
     misc_feature    complement(order(472282..472287,472291..472293,
                     472348..472350,472354..472359,472468..472470,
                     472474..472482,472606..472617,472624..472626,
                     472630..472632,472720..472722,472825..472830,
                     473032..473034))
                     /gene="fba"
                     /locus_tag="BCG_0401c"
                     /note="active site"
                     /db_xref="CDD:238255"
     misc_feature    complement(order(472240..472242,472249..472251,
                     472261..472263,472270..472275,472279..472284,
                     472606..472608,472867..472872,472879..472881,
                     472891..472893,472930..472938,472945..472947,
                     473008..473010,473017..473025))
                     /gene="fba"
                     /locus_tag="BCG_0401c"
                     /note="intersubunit interface [polypeptide binding]; other
                     site"
                     /db_xref="CDD:238255"
     misc_feature    complement(order(472357..472359,472477..472479,
                     472609..472611,472630..472632,472720..472722,
                     472825..472827))
                     /gene="fba"
                     /locus_tag="BCG_0401c"
                     /note="zinc binding site [ion binding]; other site"
                     /db_xref="CDD:238255"
     misc_feature    complement(order(472348..472350,472354..472356,
                     472468..472470,472474..472476,472480..472482))
                     /gene="fba"
                     /locus_tag="BCG_0401c"
                     /note="Na+ binding site [ion binding]; other site"
                     /db_xref="CDD:238255"
     gene            473208..473891
                     /locus_tag="BCG_0402"
                     /db_xref="GeneID:4695684"
     CDS             473208..473891
                     /locus_tag="BCG_0402"
                     /note="Differs from Rv0364 by 1aa, L193I"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_976500.1"
                     /db_xref="GI:121636277"
                     /db_xref="GeneID:4695684"
                     /translation="MSTAVTAMPDILDPMYWLGANGVFGSAVLPGILIIVFIETGLLF
                     PLLPGESLLFTGGLLSASPAPPVTIGVLAPCVALVAVLGDQTAYFIGRRIGPALFKKE
                     DSRFFKKHYVTESHAFFEKYGKWTIILARFVPIARTFVPVIAGVSYMRYPVFLGFDIV
                     GGVAWGAGVTLAGYFLGSVPFVHMNFQLIILALVFVSLLPALVSAARVYRARRNAPQS
                     DPDPLVLPE"
     misc_feature    473277..473852
                     /locus_tag="BCG_0402"
                     /note="SNARE associated Golgi protein; Region:
                     SNARE_assoc; cl00429"
                     /db_xref="CDD:260418"
     gene            complement(473880..475010)
                     /locus_tag="BCG_0403c"
                     /db_xref="GeneID:4695525"
     CDS             complement(473880..475010)
                     /locus_tag="BCG_0403c"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_976501.1"
                     /db_xref="GI:121636278"
                     /db_xref="GeneID:4695525"
                     /translation="MNLANRAASAETAVTQRHLRRLWALPGTQLAVVAWPSTRRDRLF
                     GSWHYWWQAHLLDCLVDAQLRDPQPQRRARINRQVRSHRVRNNFSWLNSYYDDMAWLA
                     LALERADRVAGVRRRRALPKLTNQFVEAWVPEDGGGIPWRKQDQFFNAPANGPAGLFL
                     ARYPDQYGKRLKRAEQMADWIDRTLIDPETHLVFDGIKAGSLVRAQYTYCQGVVLGLE
                     TELAVRTGPAARARHCARVHRLVAAVNEHMAPLGVLRGAGGGDGGLFAGITARYLALV
                     ATTLPGDSADDAAARDTARAIVLASAQSAWDYRQTVDGLPVFGAFWDREAELPTAGGE
                     QARSVRGAVHSSAIAERDLSVQLSGWMLMEAAHSAAAVSSLG"
     misc_feature    complement(473883..474998)
                     /locus_tag="BCG_0403c"
                     /note="Predicted glycosyl hydrolase [Carbohydrate
                     transport and metabolism]; Region: COG4833"
                     /db_xref="CDD:227170"
     gene            complement(475035..475628)
                     /locus_tag="BCG_0404c"
                     /db_xref="GeneID:4695589"
     CDS             complement(475035..475628)
                     /locus_tag="BCG_0404c"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_976502.1"
                     /db_xref="GI:121636279"
                     /db_xref="GeneID:4695589"
                     /translation="MKRLDLVAGPNGAGKSTFVALTLAPLLPGIVFVNADEIAKQRWP
                     DDPTSHAYQAAQVAADTRARLIDLGRPFIAETVFSHPSKLELIRTARTAGYTVVLHVL
                     VIPEGLAVERVRHRVAAGGHDVPETKIRERHRRLAELVAQAITLADGATVYDNSRLAG
                     PRIVAQFSGGGIIGRACWPSWTPPPLMSRWSNRPETA"
     misc_feature    complement(475068..475628)
                     /locus_tag="BCG_0404c"
                     /note="Uncharacterized protein conserved in bacteria
                     [Function unknown]; Region: COG4185"
                     /db_xref="CDD:226648"
     misc_feature    complement(475212..475613)
                     /locus_tag="BCG_0404c"
                     /note="AAA domain; Region: AAA_33; pfam13671"
                     /db_xref="CDD:257977"
     misc_feature    complement(475581..475604)
                     /locus_tag="BCG_0404c"
                     /note="Walker A/P-loop; other site"
                     /db_xref="CDD:213179"
     misc_feature    complement(order(475578..475586,475590..475595))
                     /locus_tag="BCG_0404c"
                     /note="ATP binding site [chemical binding]; other site"
                     /db_xref="CDD:213179"
     gene            complement(475657..476046)
                     /locus_tag="BCG_0405c"
                     /db_xref="GeneID:4698009"
     CDS             complement(475657..476046)
                     /locus_tag="BCG_0405c"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_976503.1"
                     /db_xref="GI:121636280"
                     /db_xref="GeneID:4698009"
                     /translation="MPKAVDRVTRVAADLVDSAAAEGARQSRSAKQQLDHWARVGRAV
                     SNQHTASRRRVEAALAGHLPMTDLTLEEGVVFNAEISAAIEERLSRTNYGDVLAAQGI
                     TTVALNDAGDIVEHRPDGTSVVLAATP"
     misc_feature    complement(<475867..476031)
                     /locus_tag="BCG_0405c"
                     /note="Protein of unknown function (DUF3423); Region:
                     DUF3423; pfam11903"
                     /db_xref="CDD:152339"
     gene            complement(476127..477338)
                     /locus_tag="BCG_0406c"
                     /db_xref="GeneID:4695835"
     CDS             complement(476127..477338)
                     /locus_tag="BCG_0406c"
                     /note="Differs from Rv0368c by 1aa, H249R, and from
                     Mb0375c by 1aa, G371S"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_976504.1"
                     /db_xref="GI:121636281"
                     /db_xref="GeneID:4695835"
                     /translation="MATPALLPGVDLAAFAAALAARLRDAGIPVSASGQASLVQALQQ
                     LVPRTPAALYWGARLTLVSRVDELATFDAVFASLFGVFGSAEPDGANRPPPPIAGPRT
                     PVAGVGHRAKRRSCAAQAQNLPWDTRSLTMASAGQGGPSRTLPDVLPSRIVARADEPF
                     DQFDPDDLRLLGAWLEATMARWPRRRSMRFESSPHGKRIDLRATMNASRSTGWESVLL
                     ARIRPRRRPRRVLLLCDVSRSMQPYAAIYLHLMRAAVLRRAGGHPEVFAFSTSLTRLT
                     SVLSHRSAEMALHRANARVTDRYGGTFIGRSVAALLAPPHGNALRGAVVIIASDGWDS
                     DPPDVLVHALTRVRRRAELLVWLNPRAAHPEFQPRAGSMAAALPYCDLFLPAHSLAGL
                     HQLLLALAGAR"
     misc_feature    complement(476130..477338)
                     /locus_tag="BCG_0406c"
                     /note="Protein containing von Willebrand factor type A
                     (vWA) domain [General function prediction only]; Region:
                     CoxE; COG3552"
                     /db_xref="CDD:226082"
     misc_feature    complement(476289..476636)
                     /locus_tag="BCG_0406c"
                     /note="Von Willebrand factor type A (vWA) domain was
                     originally found in the blood coagulation protein von
                     Willebrand factor (vWF). Typically, the vWA domain is made
                     up of approximately 200 amino acid residues folded into a
                     classic a/b para-rossmann type of...; Region: vWFA;
                     cd00198"
                     /db_xref="CDD:238119"
     misc_feature    complement(order(476349..476351,476433..476435,
                     476634..476636))
                     /locus_tag="BCG_0406c"
                     /note="metal ion-dependent adhesion site (MIDAS); other
                     site"
                     /db_xref="CDD:238119"
     gene            complement(477344..477859)
                     /locus_tag="BCG_0407c"
                     /db_xref="GeneID:4695431"
     CDS             complement(477344..477859)
                     /locus_tag="BCG_0407c"
                     /EC_number="1.-.-.-"
                     /codon_start=1
                     /transl_table=11
                     /product="membrane oxidoreductase"
                     /protein_id="YP_976505.1"
                     /db_xref="GI:121636282"
                     /db_xref="GeneID:4695431"
                     /translation="MPGAQLIGHEGDEYLGKVKVKVGPVTSEFSGKVHFVEQDRNQHR
                     AVFDAKGKEARGTGNAAATVAAQLHEVGERTRVTVDTDLKIVGKLAQFGSGMLQQVSE
                     KLLGQFVDSLEAELAAQSSESPQGTPPATEAAPIDLLQLADGGQLKKYGSALLAALTV
                     LLLIWVLRRRR"
     misc_feature    complement(477506..477859)
                     /locus_tag="BCG_0407c"
                     /note="Ligand-binding SRPBCC domain of an uncharacterized
                     subfamily of proteins; Region: SRPBCC_5; cd07823"
                     /db_xref="CDD:176865"
     misc_feature    complement(order(477524..477526,477533..477541,
                     477545..477553,477557..477571,477611..477613,
                     477617..477619,477623..477625,477629..477631,
                     477659..477661,477665..477667,477671..477676,
                     477719..477721,477725..477727,477755..477757,
                     477761..477763,477806..477808,477812..477814,
                     477818..477820,477824..477826,477848..477850))
                     /locus_tag="BCG_0407c"
                     /note="putative hydrophobic ligand binding site [chemical
                     binding]; other site"
                     /db_xref="CDD:176865"
     gene            complement(477960..478856)
                     /locus_tag="BCG_0408c"
                     /db_xref="GeneID:4697476"
     CDS             complement(477960..478856)
                     /locus_tag="BCG_0408c"
                     /EC_number="1.-.-.-"
                     /note="Differs from Rv0370c by 1aa, E201G"
                     /codon_start=1
                     /transl_table=11
                     /product="oxidoreductase"
                     /protein_id="YP_976506.1"
                     /db_xref="GI:121636283"
                     /db_xref="GeneID:4697476"
                     /translation="MTFASPDDVIRRFDEQNYLLDTGTASAIYLAVTLGRPLLLEGEP
                     GVGKTTAAKTLAVVLDTTLIRLQCYEGLTANEALYDWNYQRQLLSIRLAEARGKGISD
                     ISEADLYTEAYLVDRPILRCVRHRGPTPPVLLIDEIDRADDEFEALLLEFLGESAVTV
                     PELGTFLAECPPIAVLTSNRSRDLHDALRRRCLYHWIDYPEPDRAAAIVRRTVPGATA
                     PLIENATQFVCTARDLDLDKPPGVAETIDWVAALVALGVADLTAADSSPALASLGALA
                     KTPDDRTQIRDAYQAFTECSHA"
     misc_feature    complement(478278..478754)
                     /locus_tag="BCG_0408c"
                     /note="ATPases associated with a variety of cellular
                     activities; Region: AAA; smart00382"
                     /db_xref="CDD:214640"
     misc_feature    complement(478281..478754)
                     /locus_tag="BCG_0408c"
                     /note="The AAA+ (ATPases Associated with a wide variety of
                     cellular Activities) superfamily represents an ancient
                     group of ATPases belonging to the ASCE (for additional
                     strand, catalytic E) division of the P-loop NTPase fold.
                     The ASCE division also includes ABC; Region: AAA; cd00009"
                     /db_xref="CDD:99707"
     misc_feature    complement(478710..478733)
                     /locus_tag="BCG_0408c"
                     /note="Walker A motif; other site"
                     /db_xref="CDD:99707"
     misc_feature    complement(order(478326..478328,478449..478451,
                     478707..478730))
                     /locus_tag="BCG_0408c"
                     /note="ATP binding site [chemical binding]; other site"
                     /db_xref="CDD:99707"
     misc_feature    complement(478446..478463)
                     /locus_tag="BCG_0408c"
                     /note="Walker B motif; other site"
                     /db_xref="CDD:99707"
     misc_feature    complement(478284..478286)
                     /locus_tag="BCG_0408c"
                     /note="arginine finger; other site"
                     /db_xref="CDD:99707"
     gene            complement(478853..479446)
                     /locus_tag="BCG_0409c"
                     /db_xref="GeneID:4696983"
     CDS             complement(478853..479446)
                     /locus_tag="BCG_0409c"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_976507.1"
                     /db_xref="GI:121636284"
                     /db_xref="GeneID:4696983"
                     /translation="MTATQITGVVLAAGRSNRLGTPKQLLPYRDTTVLGATLDVARQA
                     GFDQLILTLGGAASAVRAAMALDGTDVVVVEDVERGCAASLRVALARVHPRATGIVLM
                     LGDQPQVAPATLRRIIDVGPATEIMVCRYADGVGHPFWFSRTVFGELARLHGDKGVWK
                     LVHSGRHPVRELAVDGCVPLDVDTWDDYRRLLESVPS"
     misc_feature    complement(478880..479431)
                     /locus_tag="BCG_0409c"
                     /note="GT_2_like_f is a subfamily of the
                     glycosyltransferase family 2 (GT-2) with unknown function;
                     Region: GT_2_like_f; cd04182"
                     /db_xref="CDD:133025"
     misc_feature    complement(order(479132..479134,479408..479410,
                     479414..479416))
                     /locus_tag="BCG_0409c"
                     /note="Ligand binding site; other site"
                     /db_xref="CDD:133025"
     misc_feature    complement(order(478898..478900,478904..478906,
                     479132..479134))
                     /locus_tag="BCG_0409c"
                     /note="metal-binding site"
                     /db_xref="CDD:133025"
     gene            complement(479443..480198)
                     /locus_tag="BCG_0410c"
                     /db_xref="GeneID:4695369"
     CDS             complement(479443..480198)
                     /locus_tag="BCG_0410c"
                     /note="Differs from Rv0372c by 1aa, G161S"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_976508.1"
                     /db_xref="GI:121636285"
                     /db_xref="GeneID:4695369"
                     /translation="MSISDRAAQLVAARTPFVRATVVRAQQPTSARPGDEAILLADGT
                     IEGFVGGHCAQNSVRKAAMGVLQAGESVLLRVLPDGDVHFPEAPGACVVVNPCLAGGS
                     LEIFLTPQLPAPLIQIYGETPIADALIELCGLLGYDARRDTDPADTDALPTAIVIASH
                     GGPEAEIIRTALDNGVGYVGLVASTVRGASILDSLDLSDAERARVHTPVGLAIGAKTP
                     AEIAVSIAAELIATLRGGGPRGRKALADENGGA"
     misc_feature    complement(479449..480198)
                     /locus_tag="BCG_0410c"
                     /note="Xanthine and CO dehydrogenases maturation factor,
                     XdhC/CoxF family [Posttranslational modification, protein
                     turnover, chaperones]; Region: XdhC; COG1975"
                     /db_xref="CDD:224886"
     misc_feature    complement(479971..480177)
                     /locus_tag="BCG_0410c"
                     /note="XdhC and CoxI family; Region: XdhC_CoxI; pfam02625"
                     /db_xref="CDD:251428"
     misc_feature    complement(479512..479847)
                     /locus_tag="BCG_0410c"
                     /note="Medium chain reductase/dehydrogenase
                     (MDR)/zinc-dependent alcohol dehydrogenase-like family;
                     Region: MDR; cl16912"
                     /db_xref="CDD:271786"
     gene            complement(480217..482616)
                     /locus_tag="BCG_0411c"
                     /db_xref="GeneID:4696547"
     CDS             complement(480217..482616)
                     /locus_tag="BCG_0411c"
                     /EC_number="1.2.99.2"
                     /note="Differs from Rv0373c by 1aa, S122F"
                     /codon_start=1
                     /transl_table=11
                     /product="carbon monoxyde dehydrogenase large chain"
                     /protein_id="YP_976509.1"
                     /db_xref="GI:121636286"
                     /db_xref="GeneID:4696547"
                     /translation="MTTIESRPPSPEDLADNAQQPCGHGRMMRKEDPRFIRGRGTYVD
                     DVALPGMLHLAILRSPYAHARIVRIDVTAAQAHPKVKAVVTGADLAAKGLAWMPTLAN
                     DVQAVLATDKTRFQGQEVASVVAEDRYSARDACELVDVDYEPRDPVVDARTALDPSAP
                     VIRTDLEGKSDNHIFDWETGDAAATEAVFAKADVVVQQEIVYPRVHPAPMETCGAVAD
                     LDPVTGKLTLWTTSQAPHAHRTLYALVAGLPEHKIRVISPDIGGGFGNKVPIYPGYVC
                     AIVASLLLDKPVKWMEDRSENLTSTGFARDYIMVGEIAANRDGKILAIRSNVLADHGA
                     FNAQAAPAKYPAGFFGVFTGSYDIEAAYCHMTAVYTNKAPGGVAYACSFRITEAVYFV
                     ERLVDCLAFELKMDPAELRLRNLLRPNQFPYQSKTGWVYDSGDYETTMRKAMNMIGYE
                     ALRAEQKQRRARGELMGIGMSFFTEAVGAGPRKDMDILGLGMADGCELRVHPTGKAVL
                     RLSVQTQGQGHETTFAQIVAEELGIAPDDIEVVHGDTDQTPFGLGTYGSRSTPVSGGA
                     AALVARKVRDKAKIIASGMLEVSVADLQWEKGKFHVKGDPSAAVTIADIAMRAHGAGD
                     LPEGIEGGLDAEVCYNPSNLTYPYGAYFCVVDIDPGTAVVKVRRFLAVDDCGTRINPM
                     IIEGQVHGGIVDGIGMALMEMIAFDEDGNCLGGSLMDYLIPTALEVPHLETGHTVTPS
                     PHHPIGAKGIGESATVGSPPAVVNAVVDALAPFGVRHADMPLTPSRVWEAMQGRATPP
                     I"
     misc_feature    complement(480247..482526)
                     /locus_tag="BCG_0411c"
                     /note="carbon-monoxide dehydrogenase, large subunit;
                     Region: CO_dehy_Mo_lg; TIGR02416"
                     /db_xref="CDD:131469"
     misc_feature    complement(482179..482505)
                     /locus_tag="BCG_0411c"
                     /note="Aldehyde oxidase and xanthine dehydrogenase, a/b
                     hammerhead domain; Region: Ald_Xan_dh_C; pfam01315"
                     /db_xref="CDD:250528"
     misc_feature    complement(480430..482133)
                     /locus_tag="BCG_0411c"
                     /note="Molybdopterin-binding domain of aldehyde
                     dehydrogenase; Region: Ald_Xan_dh_C2; pfam02738"
                     /db_xref="CDD:251506"
     gene            complement(482613..483092)
                     /locus_tag="BCG_0412c"
                     /db_xref="GeneID:4696006"
     CDS             complement(482613..483092)
                     /locus_tag="BCG_0412c"
                     /EC_number="1.2.99.2"
                     /codon_start=1
                     /transl_table=11
                     /product="carbon monoxyde dehydrogenase small chain"
                     /protein_id="YP_976510.1"
                     /db_xref="GI:121636287"
                     /db_xref="GeneID:4696006"
                     /translation="MQVNMTVNGEPVTAEVEPRMLLVHFLRDQLRLTGTHWGCDTSNC
                     GTCVVEVDGVPVKSCTMLAVMASGHSIRTVEGLAGPDGQLDPVQEGFMRCHGLQCGFC
                     TPGMLITARALLDRNPDPDEQTIREAISGQICRCTGYTTIVRSIQWAAAHQTVKAQS"
     misc_feature    complement(482634..483092)
                     /locus_tag="BCG_0412c"
                     /note="Aerobic-type carbon monoxide dehydrogenase, small
                     subunit CoxS/CutS homologs [Energy production and
                     conversion]; Region: CoxS; COG2080"
                     /db_xref="CDD:224991"
     misc_feature    complement(<482937..483086)
                     /locus_tag="BCG_0412c"
                     /note="2Fe-2S iron-sulfur cluster binding domain.
                     Iron-sulfur proteins play an important role in electron
                     transfer processes and in various enzymatic reactions. The
                     family includes plant and algal ferredoxins, which act as
                     electron carriers in photosynthesis...; Region: fer2;
                     cd00207"
                     /db_xref="CDD:238126"
     misc_feature    complement(order(482952..482963,482967..482969,
                     482976..482978,482985..482990))
                     /locus_tag="BCG_0412c"
                     /note="catalytic loop [active]"
                     /db_xref="CDD:238126"
     misc_feature    complement(order(482952..482954,482961..482963,
                     482976..482978))
                     /locus_tag="BCG_0412c"
                     /note="iron binding site [ion binding]; other site"
                     /db_xref="CDD:238126"
     misc_feature    complement(482652..482876)
                     /locus_tag="BCG_0412c"
                     /note="[2Fe-2S] binding domain; Region: Fer2_2; pfam01799"
                     /db_xref="CDD:250876"
     gene            complement(483107..483967)
                     /locus_tag="BCG_0413c"
                     /db_xref="GeneID:4696726"
     CDS             complement(483107..483967)
                     /locus_tag="BCG_0413c"
                     /EC_number="1.2.99.2"
                     /codon_start=1
                     /transl_table=11
                     /product="carbon monoxyde dehydrogenase medium chain"
                     /protein_id="YP_976511.1"
                     /db_xref="GI:121636288"
                     /db_xref="GeneID:4696726"
                     /translation="MDHAIGLLDRLGEGARVVAGGHSLLPMMKLRIANPEYLVDINDL
                     APELGYVVVGGINNPNLVRLGAMTRHREILDSDALAAVCPIFRDAERVIADPVVRNRG
                     TLGGSLCQADPAEDLSTVCTVLDAVCLAKGPSGEREIAIDDFLVGPYETALAHNEVLI
                     EVRIPLRHNTSSAYAKVERRVGDWAITAAGAAVTLDGQTILAARVGLTAVNPDPVALA
                     ELSAGLVGQPATEEVFAEAGRRAAQACTPVTDVRGTAEYKRHLAGELTVRTLRTAAGR
                     VLGAPAAPEA"
     misc_feature    complement(483470..483967)
                     /locus_tag="BCG_0413c"
                     /note="FAD binding domain in molybdopterin dehydrogenase;
                     Region: FAD_binding_5; pfam00941"
                     /db_xref="CDD:250245"
     misc_feature    complement(483140..483964)
                     /locus_tag="BCG_0413c"
                     /note="Aerobic-type carbon monoxide dehydrogenase, middle
                     subunit CoxM/CutM homologs [Energy production and
                     conversion]; Region: CoxM; COG1319"
                     /db_xref="CDD:224238"
     misc_feature    complement(483149..483451)
                     /locus_tag="BCG_0413c"
                     /note="CO dehydrogenase flavoprotein C-terminal domain;
                     Region: CO_deh_flav_C; smart01092"
                     /db_xref="CDD:215021"
     gene            complement(484043..485185)
                     /locus_tag="BCG_0414c"
                     /db_xref="GeneID:4697103"
     CDS             complement(484043..485185)
                     /locus_tag="BCG_0414c"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_976512.1"
                     /db_xref="GI:121636289"
                     /db_xref="GeneID:4697103"
                     /translation="MAIWAAGDTAGVATVVRTLRSAPRPPGAAMVVAPDGSVSGSVSG
                     GCVEGAVYELAAEVAQTGIPRLEHYGVSDDTAFAVGLTCGGIIDVFVEPVSRATFPEL
                     GELADDIGAQRPVAIATVIAHPDERRVGRRLVIRPDTKSPVTGSLGSARADAAVIDDA
                     RGLLAVGRSEILEYGPDGQRRGEGMEVFVSSHAPRPRMLVFGAIDFAAALARQGSFLG
                     YRVTVCDARAVFATPARFPTADDVVVAWPHRYLAAQAEAGGIDERTVICVLTHDPKFD
                     VPVLEVALRLGVGYVGAMGSRKTHDDRMDRLRAAGLTDAELSRLSSPIGLDLGARTPE
                     ETAVSIAADIIARRWGGGGRPLADIAGRIHHDAQVAGEFKDYLTRH"
     misc_feature    complement(484973..485182)
                     /locus_tag="BCG_0414c"
                     /note="XdhC and CoxI family; Region: XdhC_CoxI; pfam02625"
                     /db_xref="CDD:251428"
     misc_feature    complement(484079..485173)
                     /locus_tag="BCG_0414c"
                     /note="Xanthine and CO dehydrogenases maturation factor,
                     XdhC/CoxF family [Posttranslational modification, protein
                     turnover, chaperones]; Region: XdhC; COG1975"
                     /db_xref="CDD:224886"
     misc_feature    complement(484658..484870)
                     /locus_tag="BCG_0414c"
                     /note="XdhC and CoxI family; Region: XdhC_CoxI; pfam02625"
                     /db_xref="CDD:251428"
     misc_feature    complement(484154..484594)
                     /locus_tag="BCG_0414c"
                     /note="XdhC Rossmann domain; Region: XdhC_C; pfam13478"
                     /db_xref="CDD:257802"
     gene            485234..486199
                     /locus_tag="BCG_0415"
                     /db_xref="GeneID:4696588"
     CDS             485234..486199
                     /locus_tag="BCG_0415"
                     /note="Differs from Rv0377 by 1aa, R302P"
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="YP_976513.1"
                     /db_xref="GI:121636290"
                     /db_xref="GeneID:4696588"
                     /translation="MTPAQLRAYSAVVRLGSVRAAAAELGLSDAGVSMHVAALRKELD
                     DPLFTRTGAGLAFTPGGLRLASRAVEILGLQQQTAIEVTEAAHGRRLLRIAASSAFAE
                     HAAPGLIELFSSRADDLSVELSVHPTSRFRELICSRAVDIAIGPASESSIGSDGSIFL
                     RPFLKYQIITVVAPNSPLAAGIPMPALLRHQQWMLGPSAGSVDGEIATMLRGLAIPES
                     QQRIFQSDAAALEEVMRVGGATLAIGFAVAKDLAAGRLVHVTGPGLDRAGEWCVATLA
                     PSARQPAVSELVGFISTPRCIQAMIRGSGVGVTRFRPKVHVTLWS"
     misc_feature    485234..486106
                     /locus_tag="BCG_0415"
                     /note="Transcriptional regulator [Transcription]; Region:
                     LysR; COG0583"
                     /db_xref="CDD:223656"
     misc_feature    485246..485416
                     /locus_tag="BCG_0415"
                     /note="Bacterial regulatory helix-turn-helix protein, lysR
                     family; Region: HTH_1; pfam00126"
                     /db_xref="CDD:249610"
     misc_feature    485486..486106
                     /locus_tag="BCG_0415"
                     /note="LysR substrate binding domain; Region:
                     LysR_substrate; pfam03466"
                     /db_xref="CDD:251977"
     misc_feature    order(485549..485554,485558..485563,485570..485572,
                     485582..485584,485588..485608,485900..485908,
                     485924..485929,485933..485938)
                     /locus_tag="BCG_0415"
                     /note="dimerization interface [polypeptide binding]; other
                     site"
                     /db_xref="CDD:176102"
     gene            486450..486671
                     /locus_tag="BCG_0416"
                     /db_xref="GeneID:4697455"
     CDS             486450..486671
                     /locus_tag="BCG_0416"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_976514.1"
                     /db_xref="GI:121636291"
                     /db_xref="GeneID:4697455"
                     /translation="MSGRWEAGNADGNGGSAGLIGSGGAGGDGGSGGATGAGGEGGDA
                     GASGSINGNAGDPGNSGERGAVGKPGAPG"
     gene            486790..487005
                     /gene="secE2"
                     /locus_tag="BCG_0417"
                     /db_xref="GeneID:4697673"
     CDS             486790..487005
                     /gene="secE2"
                     /locus_tag="BCG_0417"
                     /codon_start=1
                     /transl_table=11
                     /product="protein transport protein secE2"
                     /protein_id="YP_976515.1"
                     /db_xref="GI:121636292"
                     /db_xref="GeneID:4697673"
                     /translation="MSVYKVIDIIGTSPTSWEQAAAEAVQRARDSVDDIRVARVIEQD
                     MAVDSAGKITYRIKLEVSFKMRPAQPR"
     misc_feature    486790..486996
                     /gene="secE2"
                     /locus_tag="BCG_0417"
                     /note="Uncharacterized conserved protein [Function
                     unknown]; Region: COG3360"
                     /db_xref="CDD:225896"
     gene            complement(487081..487632)
                     /locus_tag="BCG_0418c"
                     /db_xref="GeneID:4697708"
     CDS             complement(487081..487632)
                     /locus_tag="BCG_0418c"
                     /EC_number="2.1.1.-"
                     /codon_start=1
                     /transl_table=11
                     /product="rna methyltransferase"
                     /protein_id="YP_976516.1"
                     /db_xref="GI:121636293"
                     /db_xref="GeneID:4697708"
                     /translation="MLLRDGDARNVVDAYRYWTREAIIADIDTRRHPLHVAIENFGHD
                     ANIGSVVRTANAFAVHTVHIVGRRRWNRRGAMVTDRYQRLCHHDSTTGLLEFAAGAGL
                     TVVAVDNVPGAARLEQTALPRECLLLFGQEGPGITDDARAGAAVTVSIAQFGSTRSIN
                     AGVAAGIAMHAWIRQHADLGRAW"
     misc_feature    complement(487096..>487614)
                     /locus_tag="BCG_0418c"
                     /note="rRNA methylases [Translation, ribosomal structure
                     and biogenesis]; Region: SpoU; COG0566"
                     /db_xref="CDD:223640"
     misc_feature    complement(487123..487536)
                     /locus_tag="BCG_0418c"
                     /note="SpoU rRNA Methylase family; Region: SpoU_methylase;
                     pfam00588"
                     /db_xref="CDD:249983"
     gene            complement(487728..488636)
                     /locus_tag="BCG_0419c"
                     /db_xref="GeneID:4697216"
     CDS             complement(487728..488636)
                     /locus_tag="BCG_0419c"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_976517.1"
                     /db_xref="GI:121636294"
                     /db_xref="GeneID:4697216"
                     /translation="MRILVAWATCGAVVLSGLTGCSGSSHSGRTYGAQSARTGESLAV
                     LGWNMSVSNLRWSGDYVLIDVDASPTDPHAPHAKPEDIRFGLYGALAHPMESAALGSC
                     GDAMAHVRDVVSPLSAPAGRLTGTVCLGPLKERSAVRGVYTYSPRDRIPGTAAAYPAA
                     FPVGMLPTNQNDAGLVVKTTSVSAWRADGMQLGKPQLGDPVAFTGNGYMLLGLEVDAV
                     PDRYRDDSAARGGPMMLLAAPTLPGRGLSPACATYGSSVLILPDALLDAVHISASLCT
                     QGEINEALLYATVATVGTHAALWTSR"
     gene            complement(488654..489193)
                     /gene="pyrE"
                     /locus_tag="BCG_0420c"
                     /db_xref="GeneID:4697528"
     CDS             complement(488654..489193)
                     /gene="pyrE"
                     /locus_tag="BCG_0420c"
                     /EC_number="2.4.2.10"
                     /note="involved in fifth step of pyrimidine biosynthesis;
                     converts orotidine 5'-phosphate and diphosphate to orotate
                     and 5-phospho-alpha-D-ribose 1-diphosphate"
                     /codon_start=1
                     /transl_table=11
                     /product="orotate phosphoribosyltransferase"
                     /protein_id="YP_976518.1"
                     /db_xref="GI:121636295"
                     /db_xref="GeneID:4697528"
                     /translation="MAGPDRAELAELVRRLSVVHGRVTLSSGREADYYVDLRRATLHH
                     RASALIGRLMRELTADWDYSVVGGLTLGADPVATAIMHAPGRPIDAFVVRKSAKAHGM
                     QRLIEGSEVTGQRVLVVEDTSTTGNSALTAVHAVQDVGGEVVGVATVVDRATGAAEAI
                     EAEGLRYRSVLGLADLGLD"
     misc_feature    complement(488681..489049)
                     /gene="pyrE"
                     /locus_tag="BCG_0420c"
                     /note="Phosphoribosyl transferase (PRT)-type I domain;
                     Region: PRTases_typeI; cd06223"
                     /db_xref="CDD:206754"
     misc_feature    complement(order(488738..488740,488810..488824,
                     488828..488836,488978..488980,488984..488986))
                     /gene="pyrE"
                     /locus_tag="BCG_0420c"
                     /note="active site"
                     /db_xref="CDD:206754"
     gene            complement(489274..490128)
                     /locus_tag="BCG_0421c"
                     /db_xref="GeneID:4697784"
     CDS             complement(489274..490128)
                     /locus_tag="BCG_0421c"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_976519.1"
                     /db_xref="GI:121636296"
                     /db_xref="GeneID:4697784"
                     /translation="MVPLWFTLSALCFVGAVVLLYVDIDRRRGRSRRRKSWARSHGFD
                     YERESTEILKRWTRGVMSTVGDVAAHNVVLGQIRGEAVYIFDLEEVATVIALHRKVGT
                     NVVVDLRLKGLKEPRESDIWLLGAIGPRMVYSTNLDAARRACDRRMVTFAHTAPDCAE
                     IMWNEQNWTLVSMPIASTRAQWDEGLRTVRQFNDLLRVLPPLPQEMPQQTGVGPRGAA
                     PGRPVAPGGPAELPPRRAQPDPATTVLPDPARRAPEPIRRDEGRSEGVRRPPPAGRNG
                     QQATNYQH"
     misc_feature    complement(<489295..>489558)
                     /locus_tag="BCG_0421c"
                     /note="Proline-rich; Region: Pro-rich; pfam15240"
                     /db_xref="CDD:259374"
     gene            complement(490269..492815)
                     /gene="clpB"
                     /locus_tag="BCG_0422c"
                     /db_xref="GeneID:4697361"
     CDS             complement(490269..492815)
                     /gene="clpB"
                     /locus_tag="BCG_0422c"
                     /EC_number="3.-.-.-"
                     /standard_name="htpM"
                     /codon_start=1
                     /transl_table=11
                     /product="endopeptidase ATP binding protein subunit B"
                     /protein_id="YP_976520.1"
                     /db_xref="GI:121636297"
                     /db_xref="GeneID:4697361"
                     /translation="MDSFNPTTKTQAALTAALQAASTAGNPEIRPAHLLMALLTQNDG
                     IAAPLLEAVGVEPATVRAETQRLLDRLPQATGASTQPQLSRESLAAITTAQQLATELD
                     DEYVSTEHVMVGLATGDSDVAKLLTGHGASPQALREAFVKVRGSARVTSPEPEATYQA
                     LQKYSTDLTARAREGKLDPVIGRDNEIRRVVQVLSRRTKNNPVLIGEPGVGKTAIVEG
                     LAQRIVAGDVPESLRDKTIVALDLGSMVAGSKYRGEFEERLKAVLDDIKNSAGQIITF
                     IDELHTIVGAGATGEGAMDAGNMIKPMLARGELRLVGATTLDEYRKHIEKDAALERRF
                     QQVYVGEPSVEDTIGILRGLKDRYEVHHGVRITDSALVAAATLSDRYITARFLPDKAI
                     DLVDEAASRLRMEIDSRPVEIDEVERLVRRLEIEEMALSKEEDEASAERLAKLRSELA
                     DQKEKLAELTTRWQNEKNAIEIVRDLKEQLEALRGESERAERDGDLAKAAELRYGRIP
                     EVEKKLDAALPQAQAREQVMLKEEVGPDDIADVVSAWTGIPAGRLLEGETAKLLRMED
                     ELGKRVIGQKAAVTAVSDAVRRSRAGVSDPNRPTGAFMFLGPTGVGKTELAKALADFL
                     FDDERAMVRIDMSEYGEKHTVARLIGAPPGYVGYEAGGQLTEAVRRRPYTVVLFDEIE
                     KAHPDVFDVLLQVLDEGRLTDGHGRTVDFRNTILILTSNLGSGGSAEQVLAAVRATFK
                     PEFINRLDDVLIFEGLNPEELVRIVDIQLAQLGKRLAQRRLQLQVSLPAKRWLAQRGF
                     DPVYGARPLRRLVQQAIGDQLAKMLLAGQVHDGDTVPVNVSPDADSLILG"
     misc_feature    complement(492609..492746)
                     /gene="clpB"
                     /locus_tag="BCG_0422c"
                     /note="Clp amino terminal domain; Region: Clp_N;
                     pfam02861"
                     /db_xref="CDD:251573"
     misc_feature    complement(490293..492743)
                     /gene="clpB"
                     /locus_tag="BCG_0422c"
                     /note="ATP-dependent chaperone ClpB; Region:
                     chaperone_ClpB; TIGR03346"
                     /db_xref="CDD:234173"
     misc_feature    complement(492381..492536)
                     /gene="clpB"
                     /locus_tag="BCG_0422c"
                     /note="Clp amino terminal domain; Region: Clp_N;
                     pfam02861"
                     /db_xref="CDD:251573"
     misc_feature    complement(491805..492275)
                     /gene="clpB"
                     /locus_tag="BCG_0422c"
                     /note="The AAA+ (ATPases Associated with a wide variety of
                     cellular Activities) superfamily represents an ancient
                     group of ATPases belonging to the ASCE (for additional
                     strand, catalytic E) division of the P-loop NTPase fold.
                     The ASCE division also includes ABC; Region: AAA; cd00009"
                     /db_xref="CDD:99707"
     misc_feature    complement(492177..492200)
                     /gene="clpB"
                     /locus_tag="BCG_0422c"
                     /note="Walker A motif; other site"
                     /db_xref="CDD:99707"
     misc_feature    complement(order(491868..491870,491982..491984,
                     492174..492197))
                     /gene="clpB"
                     /locus_tag="BCG_0422c"
                     /note="ATP binding site [chemical binding]; other site"
                     /db_xref="CDD:99707"
     misc_feature    complement(491979..491996)
                     /gene="clpB"
                     /locus_tag="BCG_0422c"
                     /note="Walker B motif; other site"
                     /db_xref="CDD:99707"
     misc_feature    complement(491817..491819)
                     /gene="clpB"
                     /locus_tag="BCG_0422c"
                     /note="arginine finger; other site"
                     /db_xref="CDD:99707"
     misc_feature    complement(491343..491570)
                     /gene="clpB"
                     /locus_tag="BCG_0422c"
                     /note="TATA element modulatory factor 1 TATA binding;
                     Region: TMF_TATA_bd; pfam12325"
                     /db_xref="CDD:256982"
     misc_feature    complement(490554..491099)
                     /gene="clpB"
                     /locus_tag="BCG_0422c"
                     /note="The AAA+ (ATPases Associated with a wide variety of
                     cellular Activities) superfamily represents an ancient
                     group of ATPases belonging to the ASCE (for additional
                     strand, catalytic E) division of the P-loop NTPase fold.
                     The ASCE division also includes ABC; Region: AAA; cd00009"
                     /db_xref="CDD:99707"
     misc_feature    complement(490974..490997)
                     /gene="clpB"
                     /locus_tag="BCG_0422c"
                     /note="Walker A motif; other site"
                     /db_xref="CDD:99707"
     misc_feature    complement(order(490653..490655,490779..490781,
                     490971..490994))
                     /gene="clpB"
                     /locus_tag="BCG_0422c"
                     /note="ATP binding site [chemical binding]; other site"
                     /db_xref="CDD:99707"
     misc_feature    complement(490776..490793)
                     /gene="clpB"
                     /locus_tag="BCG_0422c"
                     /note="Walker B motif; other site"
                     /db_xref="CDD:99707"
     misc_feature    complement(490578..490580)
                     /gene="clpB"
                     /locus_tag="BCG_0422c"
                     /note="arginine finger; other site"
                     /db_xref="CDD:99707"
     misc_feature    complement(490308..490550)
                     /gene="clpB"
                     /locus_tag="BCG_0422c"
                     /note="C-terminal, D2-small domain, of ClpB protein;
                     Region: ClpB_D2-small; pfam10431"
                     /db_xref="CDD:255983"
     gene            492948..494120
                     /locus_tag="BCG_0423"
                     /db_xref="GeneID:4697010"
     CDS             492948..494120
                     /locus_tag="BCG_0423"
                     /EC_number="1.-.-.-"
                     /codon_start=1
                     /transl_table=11
                     /product="monooxygenase"
                     /protein_id="YP_976521.1"
                     /db_xref="GI:121636298"
                     /db_xref="GeneID:4697010"
                     /translation="MGLEDRDALRVLQNAFKLDDPELVRRFYAHWFALDASVRDLFPP
                     DMGAQRAAFGQALHWVYGELVAQRAEEPVAFLAQLGRDHRKYGVLPTQYDTLRRALYT
                     TLRDYLGHPSRGAWTDAVDEAAGQSLNLIIGVMSGAADADDAPAWWDGTVVEHIRVSR
                     DLAVARLQLDRPLHYYPGQYVNVHVPQCPRRWRYLSPAIPADPNGRIEFHVRVVPGGL
                     VSNAIVGETRPGDRWRLSGPHGAFRVDRDGGDVLMVAGSTGLAPLRALIIDLSRFAVN
                     PRVHLFFGARYACELYDLPTLWQIAAHNPWLSVSPVSEYNGDPAWAADYPDVSAPRGL
                     HVRQTGRLPDVVSRYGGWGDRQILICGGPAMVRATKAALIAKGAPPERIQHDPLSR"
     misc_feature    492981..493352
                     /locus_tag="BCG_0423"
                     /note="myoglobin_like; M family globin domain; Region:
                     Mb_like; cd01040"
                     /db_xref="CDD:271266"
     misc_feature    493008..494096
                     /locus_tag="BCG_0423"
                     /note="bifunctional nitric oxide
                     dioxygenase/dihydropteridine reductase 2; Provisional;
                     Region: PRK13289"
                     /db_xref="CDD:237337"
     misc_feature    order(493068..493073,493092..493094,493101..493106,
                     493113..493115,493182..493184,493191..493196,
                     493209..493211,493221..493226,493233..493235)
                     /locus_tag="BCG_0423"
                     /note="heme binding site [chemical binding]; other site"
                     /db_xref="CDD:271266"
     misc_feature    493401..494108
                     /locus_tag="BCG_0423"
                     /note="The oxygenase reductase FAD/NADH binding domain
                     acts as part of the multi-component bacterial oxygenases
                     which oxidize hydrocarbons using oxygen as the oxidant.
                     Electron transfer is from NADH via FAD (in the oxygenase
                     reductase) and an [2FE-2S]...; Region:
                     O2ase_reductase_like; cd06187"
                     /db_xref="CDD:99784"
     misc_feature    order(493485..493487,493524..493535,493575..493583,
                     493587..493589,493599..493607,493719..493721,
                     493728..493730,494103..494105)
                     /locus_tag="BCG_0423"
                     /note="FAD binding pocket [chemical binding]; other site"
                     /db_xref="CDD:99784"
     misc_feature    order(493524..493526,493530..493535)
                     /locus_tag="BCG_0423"
                     /note="FAD binding motif [chemical binding]; other site"
                     /db_xref="CDD:99784"
     misc_feature    order(493596..493598,493605..493607,493614..493616,
                     493635..493637,493659..493661,493665..493667)
                     /locus_tag="BCG_0423"
                     /note="phosphate binding motif [ion binding]; other site"
                     /db_xref="CDD:99784"
     misc_feature    order(493704..493706,493716..493727,493731..493733)
                     /locus_tag="BCG_0423"
                     /note="beta-alpha-beta structure motif; other site"
                     /db_xref="CDD:99784"
     misc_feature    order(493719..493724,493797..493805,494028..494033)
                     /locus_tag="BCG_0423"
                     /note="NAD binding pocket [chemical binding]; other site"
                     /db_xref="CDD:99784"
     gene            494224..497481
                     /locus_tag="BCG_0424"
                     /db_xref="GeneID:4697702"
     CDS             494224..497481
                     /locus_tag="BCG_0424"
                     /note="Differs from Mb0393 by 1aa, D902A"
                     /codon_start=1
                     /transl_table=11
                     /product="LuxR family transcriptional regulator"
                     /protein_id="YP_976522.1"
                     /db_xref="GI:121636299"
                     /db_xref="GeneID:4697702"
                     /translation="MSKLLPRGTVTLLLADVEGSTWLWETHPDDMGAAVARLDKAVSG
                     VIAAHDGVRPVEQGEGDSFVLAFACASDAVAAALDLQRARLAPIRLRIGVHTGEVALR
                     DEGNYAGPTINRTARLRDLAHGGQTVLSGVTESLVIDRLPDKAWLVDLGTHALRDLSR
                     PERVMQLCHPELRIDFPPLRVANDDVAHGLPVHLTRFVGRGAQITEVHRLVTDNRLVT
                     LTGAGGVGKTRLAAQLAAQIAGEFGRAWFVDLAPITDPDLVPVTVAGALGLHDQPGRS
                     TTDTVLRFLGGRPALVVLDNCEHLLDATAALVLALVKACRGVRLLATCREPLRVEGEV
                     SYRVPSLSLSDEAVEMFCYRAQRVRPDFRLTDDNSAAVTEICKRLDGLPLAIELAAAR
                     LRSMTLDEIIDGLRDRFALLTGGARTAAHRQQTLWASVDWSYTLLTEPERTLFRRLAV
                     FVGCFFVDDAQAVACSGDVQRYQVLDEITLLVDKSLVMADDNSGRTCYRLCETMRHYA
                     LEKLSEAGEVDAVFARHRDYYTALAARVDNPGPSDYSHCLDQAETEIDNLRAAFVWNR
                     ENSDTEGALALASSLLRVWMTRGRIQEGRAWFDSILADENARHLEVAAAVRARALADK
                     ALLDIFVDAAAGMEQAQQALVIAREVDEPALLSRALTACGLIAVAVARADAAASYFAE
                     AIDLARAVDDRWRLAQILTFQAVDAVVAGDPVAARPAAQEARELAAAIGDHSNALWCR
                     WCLGYAQLMRGELAAAAAQFGEVVDEAEASQEVLHKANSLQGLAFALAYQGELSAARA
                     AADAALEAAELGEYFAGMGYSALTTAALAAGDVQTAQHASEAAWRNLSLALPLSAAVQ
                     RAFNAQAALAGGDLSAARRWCDDAVQSMTGHHLAMALATRARIAVAEGKREEAERDAH
                     KALACAAESGAHLDLPDVLECLAGLASDAGTHHAAARLFGAAEAIRQQIGSVRFAIYR
                     SDYVQSVTALRDAMGEKDFDAAWAEGAALSIKETIAYAQRGHSWRKRPATGWESLTPT
                     EIDVVRLVGEGLANKDIATRLFVSPRTVQTHLTHVYTKLGFTSRLQLAQAAARRT"
     misc_feature    494248..494754
                     /locus_tag="BCG_0424"
                     /note="Adenylate cyclase, family 3 (some proteins contain
                     HAMP domain) [Signal transduction mechanisms]; Region:
                     CyaA; COG2114"
                     /db_xref="CDD:225025"
     misc_feature    494248..494724
                     /locus_tag="BCG_0424"
                     /note="cyclase homology domain; Region: CHD; cd07302"
                     /db_xref="CDD:143636"
     misc_feature    order(494263..494265,494269..494286,494392..494394,
                     494398..494406,494413..494415,494539..494547,
                     494557..494562,494569..494574,494689..494691)
                     /locus_tag="BCG_0424"
                     /note="nucleotidyl binding site; other site"
                     /db_xref="CDD:143636"
     misc_feature    order(494269..494271,494404..494406)
                     /locus_tag="BCG_0424"
                     /note="metal binding site [ion binding]; metal-binding
                     site"
                     /db_xref="CDD:143636"
     misc_feature    order(494284..494286,494317..494319,494326..494331,
                     494338..494340,494350..494352,494392..494397,
                     494542..494553,494560..494562,494689..494691)
                     /locus_tag="BCG_0424"
                     /note="dimer interface [polypeptide binding]; other site"
                     /db_xref="CDD:143636"
     misc_feature    494827..496053
                     /locus_tag="BCG_0424"
                     /note="Predicted ATPase [General function prediction
                     only]; Region: COG3903"
                     /db_xref="CDD:226418"
     misc_feature    <497158..497475
                     /locus_tag="BCG_0424"
                     /note="Response regulator containing a CheY-like receiver
                     domain and an HTH DNA-binding domain [Signal transduction
                     mechanisms / Transcription]; Region: CitB; COG2197"
                     /db_xref="CDD:225107"
     misc_feature    497302..497472
                     /locus_tag="BCG_0424"
                     /note="C-terminal DNA-binding domain of LuxR-like
                     proteins. This domain contains a helix-turn-helix motif
                     and binds DNA. Proteins belonging to this group are
                     response regulators; some act as transcriptional
                     activators, others as transcriptional repressors. Many...;
                     Region: LuxR_C_like; cd06170"
                     /db_xref="CDD:99777"
     misc_feature    order(497305..497313,497350..497358,497380..497385,
                     497389..497394,497398..497412,497443..497445)
                     /locus_tag="BCG_0424"
                     /note="DNA binding residues [nucleotide binding]"
                     /db_xref="CDD:99777"
     misc_feature    order(497338..497340,497344..497346,497350..497352,
                     497443..497451,497458..497460,497467..497472)
                     /locus_tag="BCG_0424"
                     /note="dimerization interface [polypeptide binding]; other
                     site"
                     /db_xref="CDD:99777"
     gene            complement(497485..498816)
                     /gene="PPE9"
                     /locus_tag="BCG_0425c"
                     /db_xref="GeneID:4696958"
     CDS             complement(497485..498816)
                     /gene="PPE9"
                     /locus_tag="BCG_0425c"
                     /note="In Mycobacterium tuberculosis strain H37Rv, Rv0388c
                     and Rv0387c exist as 2 separate genes. In Mycobacterium
                     bovis BCG Pasteur, and Mycobacterium bovis, 3 different
                     base substitutions, the first of 14 bases, the second of 8
                     bases (tctacagt-gctacagg), and lastly of 28 bases, leads
                     to a longer single product;
                     Differs from Mb0394c by 1aa, T361A"
                     /codon_start=1
                     /transl_table=11
                     /product="PPE family protein"
                     /protein_id="YP_976523.1"
                     /db_xref="GI:121636300"
                     /db_xref="GeneID:4696958"
                     /translation="MDFGALPPEINSARIYSGPGSRPLMQAAAAWQRLANELTATAAS
                     YSSVISGLTGDDWLGPSALSMAAAAVPYVAWMRATAASAEQAAAQAVAAANAYESAYA
                     ATVPPTVIAANRRTMLSLVKTNVFGQNTPAIATSEAQYGAMWAQDIVAMEGYAGASAA
                     ASQLPPFTPPPATTSGAGSLSDAAATAAQAVVPAAAATDVSLLPTLQSFLPPPFDAIP
                     NPIEDLDVLVAAAVAVAAGSLGVSAAQLGEIYRHDVVDEAQKAPHCPAESDQTPAGAA
                     GDGDLPEVGGRVTSPPQPPVAALTGYSANIGGLSVPHSWNLPPAVRQVAAMFPGATPM
                     YMTGSSDGSYAGLAAAGLAGTGLAGLTARGGSAPTPAAAAPAGAGGAGPAATRPAAQQ
                     TPAVPAAAAGSAIPGLPPGLPPGVVANLAATLAAIPGATIIVVPPSPNANQ"
     misc_feature    complement(<497800..498816)
                     /gene="PPE9"
                     /locus_tag="BCG_0425c"
                     /note="PPE-repeat proteins [Cell motility and secretion];
                     Region: COG5651"
                     /db_xref="CDD:227938"
     misc_feature    complement(498361..498804)
                     /gene="PPE9"
                     /locus_tag="BCG_0425c"
                     /note="PPE family; Region: PPE; pfam00823"
                     /db_xref="CDD:250158"
     gene            499150..500409
                     /gene="purT"
                     /locus_tag="BCG_0426"
                     /db_xref="GeneID:4696418"
     CDS             499150..500409
                     /gene="purT"
                     /locus_tag="BCG_0426"
                     /EC_number="2.1.2.-"
                     /note="non-folate utilizing enzyme, catalyzes the
                     production of beta-formyl glycinamide ribonucleotide from
                     formate, ATP, and beta-GAR and a side reaction producing
                     acetyl phosphate and ADP from acetate and ATP; involved in
                     de novo purine biosynthesis"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylglycinamide formyltransferase 2"
                     /protein_id="YP_976524.1"
                     /db_xref="GI:121636301"
                     /db_xref="GeneID:4696418"
                     /translation="MIDGWTEGQHEPTVRHERPAAPQDVRRVMLLGSAEPSRELAIAL
                     QGLGAEVIAVDGYVGAPAHRIADQSVVVTMTDAEELTAVIRRLQPDFLVTVTAAVSVD
                     ALDAVEQADGECTELVPNARAVRCTADREGLRRLAADQLGLPTAPFWFVGSLGELQAV
                     AVHAGFPLLVSPVAGVAGQGSSVVAGPNEVEPAWQRAAGHQVQPQTGGVSPRVCAESV
                     VEIEFLVTMIVVCSQGPNGPLIEFCAPIGHRDADAGELESWQPQKLSTAALDAAKSIA
                     ARIVKALGGRGVFGVELMINGDEVYFADVTVCPAGSAWVTVRSQRLSVFELQARATLG
                     LAVDTLMISPGAARVINPDHTAGRAAVGAAPPADALTGALGVPESDVVIFGRGLGVAL
                     ATAPEVAIARERAREVASRLNVPDSRE"
     misc_feature    499186..500397
                     /gene="purT"
                     /locus_tag="BCG_0426"
                     /note="Formate-dependent phosphoribosylglycinamide
                     formyltransferase (GAR transformylase) [Nucleotide
                     transport and metabolism]; Region: PurT; COG0027"
                     /db_xref="CDD:223106"
     misc_feature    499246..>499470
                     /gene="purT"
                     /locus_tag="BCG_0426"
                     /note="Signal receiver domain; originally thought to be
                     unique to bacteria (CheY, OmpR, NtrC, and PhoB), now
                     recently identified in eukaroytes ETR1 Arabidopsis
                     thaliana; this domain receives the signal from the sensor
                     partner in a two-component systems; Region: REC; cl19078"
                     /db_xref="CDD:271833"
     misc_feature    499561..500028
                     /gene="purT"
                     /locus_tag="BCG_0426"
                     /note="ATP-grasp domain; Region: ATP-grasp_4; cl17255"
                     /db_xref="CDD:271806"
     gene            500406..500828
                     /locus_tag="BCG_0427"
                     /db_xref="GeneID:4696059"
     CDS             500406..500828
                     /locus_tag="BCG_0427"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_976525.1"
                     /db_xref="GI:121636302"
                     /db_xref="GeneID:4696059"
                     /translation="MSYAGDITPLQAWEMLSDNPRAVLVDVRCEAEWRFVGVPDLSSL
                     GREVVYVEWATSDGTHNDNFLAELRDRIPADADQHERPVIFLCRSGNRSIGAAEVATE
                     AGITPAYNVLDGFEGHLDAEGHRGATGWRAVGLPWRQG"
     misc_feature    500424..500801
                     /locus_tag="BCG_0427"
                     /note="Member of the Rhodanese Homology Domain
                     superfamily, subgroup 1. This CD includes the putative
                     rhodanese-related sulfurtransferases of several
                     uncharacterized proteins; Region: RHOD_1; cd01522"
                     /db_xref="CDD:238780"
     misc_feature    500664..500666
                     /locus_tag="BCG_0427"
                     /note="active site residue [active]"
                     /db_xref="CDD:238780"
     gene            500825..502045
                     /gene="metZ"
                     /locus_tag="BCG_0428"
                     /db_xref="GeneID:4696910"
     CDS             500825..502045
                     /gene="metZ"
                     /locus_tag="BCG_0428"
                     /EC_number="4.2.99.-"
                     /codon_start=1
                     /transl_table=11
                     /product="O-succinylhomoserine sulfhydrylase"
                     /protein_id="YP_976526.1"
                     /db_xref="GI:121636303"
                     /db_xref="GeneID:4696910"
                     /translation="MTDESSVRTPKALPDGVSQATVGVRGGMLRSGFEETAEAMYLTS
                     GYVYGSAAVAEKSFAGELDHYVYSRYGNPTVSVFEERLRLIEGAPAAFATASGMAAVF
                     TSLGALLGAGDRLVAARSLFGSCFVVCSEILPRWGVQTVFVDGDDLSQWERALSVPTQ
                     AVFFETPSNPMQSLVDIAAVTELAHAAGAKVVLDNVFATPLLQQGFPLGVDVVVYSGT
                     KHIDGQGRVLGGAILGDREYIDGPVQKLMRHTGPAMSAFNAWVLLKGLETLAIRVQHS
                     NASAQRIAEFLNGHPSVRWVRYPYLPSHPQYDLAKRQMSGGGTVVTFALDCPEDVAKQ
                     RAFEVLDKMRLIDISNNLGDAKSLVTHPATTTHRAMGPEGRAAIGLGDGVVRISVGLE
                     DTDDLIADIDRALS"
     misc_feature    500945..502042
                     /gene="metZ"
                     /locus_tag="BCG_0428"
                     /note="CGS_like: Cystathionine gamma-synthase is a PLP
                     dependent enzyme and catalyzes the committed step of
                     methionine biosynthesis. This pathway is unique to
                     microorganisms and plants, rendering the enzyme an
                     attractive target for the development of...; Region:
                     CGS_like; cd00614"
                     /db_xref="CDD:99738"
     misc_feature    order(500948..500959,500963..500968,501023..501025,
                     501029..501031,501107..501112,501116..501121,
                     501188..501190,501203..501205,501212..501214,
                     501476..501478,501500..501502,501506..501508,
                     501557..501559,501587..501589,501593..501598,
                     501845..501847)
                     /gene="metZ"
                     /locus_tag="BCG_0428"
                     /note="homodimer interface [polypeptide binding]; other
                     site"
                     /db_xref="CDD:99738"
     misc_feature    500948..501736
                     /gene="metZ"
                     /locus_tag="BCG_0428"
                     /note="Beta-eliminating lyase; Region: Beta_elim_lyase;
                     pfam01212"
                     /db_xref="CDD:250447"
     misc_feature    order(501110..501118,501188..501190,501317..501319,
                     501404..501406,501470..501472,501476..501481,
                     501506..501508)
                     /gene="metZ"
                     /locus_tag="BCG_0428"
                     /note="substrate-cofactor binding pocket; other site"
                     /db_xref="CDD:99738"
     misc_feature    order(501110..501118,501188..501190,501404..501406,
                     501413..501415,501470..501472,501476..501481)
                     /gene="metZ"
                     /locus_tag="BCG_0428"
                     /note="pyridoxal 5'-phosphate binding site [chemical
                     binding]; other site"
                     /db_xref="CDD:99738"
     misc_feature    501479..501481
                     /gene="metZ"
                     /locus_tag="BCG_0428"
                     /note="catalytic residue [active]"
                     /db_xref="CDD:99738"
     gene            complement(502042..503454)
                     /gene="ndhA"
                     /locus_tag="BCG_0429c"
                     /db_xref="GeneID:4699106"
     CDS             complement(502042..503454)
                     /gene="ndhA"
                     /locus_tag="BCG_0429c"
                     /EC_number="1.6.99.3"
                     /note="Differs from Rv0392c by 1aa, A241V"
                     /codon_start=1
                     /transl_table=11
                     /product="membrane NADH dehydrogenase ndhA"
                     /protein_id="YP_976527.1"
                     /db_xref="GI:121636304"
                     /db_xref="GeneID:4699106"
                     /translation="MTLSSGEPSAVGGRHRVVIIGSGFGGLNAAKALKRADVDITLIS
                     KTTTHLFQPLLYQVATGILSEGDIAPTTRLILRRQKNVRVLLGEVNAIDLKAQTVTSK
                     LMDMTTVTPYDSLIVAAGAQQSYFGNDEFATFAPGMKTIDDALELRGRILGAFEAAEV
                     STDHAERERRLTFVVVGAGPTGVEVAGQIVELAERTLAGAFRTITPSECRVILLDAAP
                     AVLPPMGPKLGLKAQRRLEKMDAEVQLNAMVTAVDYKGITIKEKDGGERRIECACKVW
                     AAGVAASPLGKMIAEGSDGTEIDRAGRVIVEPDLTVKGHPNVFVVGDLMFVPGVPGVA
                     QGAIQGARYATTVIKHMVKGNDDPANRKPFHYFNKGSMATISRHSAVAQVGKLEFAGY
                     FAWLAWLVLHLVYLVGYRNRIAALFAWGISFMGRARGQMAITSQMIYARLVMTLMEQQ
                     AQGALAAAEQAEHAEQEAAG"
     misc_feature    complement(502165..503415)
                     /gene="ndhA"
                     /locus_tag="BCG_0429c"
                     /note="NADH dehydrogenase, FAD-containing subunit [Energy
                     production and conversion]; Region: Ndh; COG1252"
                     /db_xref="CDD:224172"
     misc_feature    complement(<503320..503400)
                     /gene="ndhA"
                     /locus_tag="BCG_0429c"
                     /note="NAD(P)-binding Rossmann-like domain; Region:
                     NAD_binding_8; pfam13450"
                     /db_xref="CDD:257775"
     misc_feature    complement(502663..502935)
                     /gene="ndhA"
                     /locus_tag="BCG_0429c"
                     /note="Pyridine nucleotide-disulphide oxidoreductase;
                     Region: Pyr_redox; pfam00070"
                     /db_xref="CDD:249559"
     gene            503596..504921
                     /locus_tag="BCG_0430"
                     /db_xref="GeneID:4696138"
     CDS             503596..504921
                     /locus_tag="BCG_0430"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_976528.1"
                     /db_xref="GI:121636305"
                     /db_xref="GeneID:4696138"
                     /translation="MAVGRCAIPRFDQAASGSAINGGQVHLSDGSTSPARQLPAPWPG
                     DAGAAAEGRAGVCCRGNRLPHVSDVGVSHRFDHRPAGVGAGGCRAGAAGAGLAVDDPG
                     QLAAAIDRIVAVADPDAVRQVRERARDREVSIWNSADGMGEVYAQLYATDAQALDARL
                     NALVATVCAGDPRSTDQRRADALGALAAGADRLACRCDNPDCAAEGRPVSAVVIHVVA
                     EQASVKGHGQAPAALLGGDGLIPAELVAELAKTAGLQPIPVPAGTEPGYRPSVKLAAF
                     VRARDLTCRAPGCDRPATQCDLDHTIAFADGGATHAANLKCLCRLHHLLATFCGWRAQ
                     QLPDGTVIWTLPGNQTYVTTPGSALLFPALCTPTGDPPAPEPARADRRGQRTAMMPRR
                     ASTRTQNRAHCIAAERHRNHQARRIAQAAVIATETHGPPPDPDDDPPPF"
     misc_feature    <503893..504438
                     /locus_tag="BCG_0430"
                     /note="Domain of unknown function (DUF222); Region:
                     DUF222; pfam02720"
                     /db_xref="CDD:251494"
     misc_feature    504409..504576
                     /locus_tag="BCG_0430"
                     /note="HNH nucleases; HNH endonuclease signature which is
                     found in viral, prokaryotic, and eukaryotic proteins. The
                     alignment includes members of the large group of homing
                     endonucleases, yeast intron 1 protein, MutS, as well as
                     bacterial colicins, pyocins, and...; Region: HNHc;
                     cd00085"
                     /db_xref="CDD:238038"
     misc_feature    order(504484..504486,504490..504498,504502..504504,
                     504535..504540,504550..504555,504562..504564,
                     504574..504576)
                     /locus_tag="BCG_0430"
                     /note="active site"
                     /db_xref="CDD:238038"
     gene            complement(504937..505656)
                     /locus_tag="BCG_0431c"
                     /db_xref="GeneID:4697365"
     CDS             complement(504937..505656)
                     /locus_tag="BCG_0431c"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_976529.1"
                     /db_xref="GI:121636306"
                     /db_xref="GeneID:4697365"
                     /translation="MTEPRPVFAVVISAGLSAIPMVGGPLQTVFDAIEERTRHRAETT
                     TREICESVGGADTVLSRIDKNPELEPLLSQAIEAATRTSMEAKRRLLAQAAAAALEDD
                     QKVEPASLIVATLSQLEPVHIHALVRLAKAAKSSPDQDEIQRREVMRAASKVEPVPVL
                     AALIQTGVAIATTTVWHGNGTGTPAEESGHILIHDVSDFGHRLLAYLRAADAGAELLI
                     LPSGGSAPTGDHPTPHPSTSR"
     gene            505755..506159
                     /locus_tag="BCG_0432"
                     /db_xref="GeneID:4696421"
     CDS             505755..506159
                     /locus_tag="BCG_0432"
                     /note="Differs from Rv0395 by 1aa, A80V"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_976530.1"
                     /db_xref="GI:121636307"
                     /db_xref="GeneID:4696421"
                     /translation="MDWMPLGDYETFRHWSGKPRAWGPQESGWRAWFGGKIVDGLCEV
                     LDEHLAVRRRGVPAAIGCVPWLSSEAVAETLLALSAFCVVIDKGTSFPSRLRNPDKGF
                     PNVALLRLRDMAPSEHGSRCSSARGRLCLSMS"
     gene            506165..506557
                     /locus_tag="BCG_0433"
                     /db_xref="GeneID:4696027"
     CDS             506165..506557
                     /locus_tag="BCG_0433"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_976531.1"
                     /db_xref="GI:121636308"
                     /db_xref="GeneID:4696027"
                     /translation="MRALGWLREDRKPLLNAKLLVLGHLALNVYDPDNGYGEEVLDFE
                     PRTVWWGSANWTVRAGSHLEVGFACDDPTLVEEATAFVADVIAFSEPIDTTCAGPEPN
                     LVQVEFDDAAMAEAMEEMAEPDDDGEDW"
     misc_feature    <506291..506404
                     /locus_tag="BCG_0433"
                     /note="PLD-like domain; Region: PLDc_2; pfam13091"
                     /db_xref="CDD:257494"
     gene            506631..506999
                     /locus_tag="BCG_0434"
                     /db_xref="GeneID:4695980"
     CDS             506631..506999
                     /locus_tag="BCG_0434"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_976532.1"
                     /db_xref="GI:121636309"
                     /db_xref="GeneID:4695980"
                     /translation="MLATFWGWRAQQLPDGTVIWTLPGDQTYVTTPGSALLFPALCTP
                     TGDPPRPDPARADRRGQRTAMMPRRASTRAQNRAHYIAAERHRNHQARRIAHVVTQTA
                     TTAPETNGPPPDPDDDPPPF"
     gene            complement(507494..508135)
                     /locus_tag="BCG_0435c"
                     /db_xref="GeneID:4697139"
     CDS             complement(507494..508135)
                     /locus_tag="BCG_0435c"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_976533.1"
                     /db_xref="GI:121636310"
                     /db_xref="GeneID:4697139"
                     /translation="MGVIARVVGVAACGLSLAVLAAAPTAGAEPTGALPPMTSSGSGP
                     VIGDGDAALRQRISQQLFSFGDPTVQEVDGSDAAQFITAAAAVADRDVASVFLPLQRV
                     LGCQQNTAGSGAGFGARAYRRTDGQWGGAMLVVAKSTVSDVDALKACVKSGWRKATAG
                     TPTSMCNNGWTYPPFADTRRGEEGYFVLLAGTASDFCSAPNANYRTTASSWPG"
     gene            complement(508142..509371)
                     /gene="lpqK"
                     /locus_tag="BCG_0436c"
                     /db_xref="GeneID:4695965"
     CDS             complement(508142..509371)
                     /gene="lpqK"
                     /locus_tag="BCG_0436c"
                     /codon_start=1
                     /transl_table=11
                     /product="lipoprotein lpqK"
                     /protein_id="YP_976534.1"
                     /db_xref="GI:121636311"
                     /db_xref="GeneID:4695965"
                     /translation="MPVLRRLGCSVLALGLLAGCAPPRTGPASSPTNNGAKADAVIRI
                     VRDFMTQAHLKAVLVRVTVAGKEVVTRAVGDSMTGVPATTAMHFRNGAVAISYVATLL
                     LKLVDEKKLRLDDKLSRWLPDFPHADRVTLGQLAQMTSGYPDYVLGNEAFDAELYANP
                     FRQWTTQELLDQISSRPLLYDPGTNWNYAHTNYLLLGLALEKAAGQDMPTLLQRKVLS
                     PLGLTATANSDTPAIPEPALHAFTSERRAALKIPAGVPFYEESTFWNPSWTITHGAIQ
                     TTTIYDMEATAVGIGSGRLLSADSYKKMVSTELRGKTRAQPGCPTCFEQNDGYSYGLG
                     IVISGHWLLQNPMFAGYAAVEAYLPSQRVAVAVAVTYAPEAFDDQGNYRNQADILFRK
                     IGAEVAPNDAPPMPPGR"
     misc_feature    complement(508202..509251)
                     /gene="lpqK"
                     /locus_tag="BCG_0436c"
                     /note="Beta-lactamase; Region: Beta-lactamase; pfam00144"
                     /db_xref="CDD:249626"
     gene            complement(509381..510568)
                     /gene="fadE7"
                     /locus_tag="BCG_0437c"
                     /db_xref="GeneID:4698158"
     CDS             complement(509381..510568)
                     /gene="fadE7"
                     /locus_tag="BCG_0437c"
                     /EC_number="1.3.99.-"
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-CoA dehydrogenase fadE7"
                     /protein_id="YP_976535.1"
                     /db_xref="GI:121636312"
                     /db_xref="GeneID:4698158"
                     /translation="MSTPTPPALDRDDPLGLDASLSSDEIAVRDTVRRFCAEHVTPHV
                     AAWFEDGDLPVARDLAKQFGELGLLGMQLHGHGCGGASAVHYGLACRELEAADSGIRS
                     LVSVQGSLAMFAIASFGSDEQKRQWLPGMATGDLLGCFGLTEPDVGSDPAAMKTRARR
                     DGPDWVITGGKMWITNGSVADVAIVWAATDDGIRGFIVPTDTPGFTANTIGHKLSLRA
                     SITSELVLDNVRLPADAMLPGATGLRAPLACLSEARYGIVWGAMGAARSAWQCALDYA
                     RQRTQFGRPIAGFQLTQAKLVDMAVELHKGQLLSLHLGRLKDRVGLRPDQVSFGKLNN
                     TREALKICRTARTILGGNGISLEYPVIRHMVNLESVLTYEGTPEMHQLVLGQAFTGLA
                     AFR"
     misc_feature    complement(509387..510544)
                     /gene="fadE7"
                     /locus_tag="BCG_0437c"
                     /note="Glutaryl-CoA dehydrogenase; Region: GCD; cd01151"
                     /db_xref="CDD:173840"
     misc_feature    complement(509384..510520)
                     /gene="fadE7"
                     /locus_tag="BCG_0437c"
                     /note="Acyl-CoA dehydrogenases [Lipid metabolism]; Region:
                     CaiA; COG1960"
                     /db_xref="CDD:224871"
     misc_feature    complement(order(509435..509437,509441..509443,
                     509462..509464,510044..510046,510050..510052,
                     510122..510127,510140..510145,510149..510151))
                     /gene="fadE7"
                     /locus_tag="BCG_0437c"
                     /note="FAD binding site [chemical binding]; other site"
                     /db_xref="CDD:173840"
     misc_feature    complement(order(509447..509452,509807..509809,
                     509816..509821,509840..509842,510122..510124))
                     /gene="fadE7"
                     /locus_tag="BCG_0437c"
                     /note="substrate binding pocket [chemical binding]; other
                     site"
                     /db_xref="CDD:173840"
     misc_feature    complement(509447..509449)
                     /gene="fadE7"
                     /locus_tag="BCG_0437c"
                     /note="catalytic base [active]"
                     /db_xref="CDD:173840"
     gene            510604..510975
                     /locus_tag="BCG_0438"
                     /db_xref="GeneID:4696258"
     CDS             510604..510975
                     /locus_tag="BCG_0438"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_976536.1"
                     /db_xref="GI:121636313"
                     /db_xref="GeneID:4696258"
                     /translation="MRPRRALAGLAADVVAVLVFCAVGRRSHAEGLSVTGLAATAWPF
                     LTGTGIGWVLARGWRRPTALAPTGVIVWLCTIVVGMVLRKVSSAGVAASFVVVASAVT
                     AVLLLGWRAAVALMAPHRADG"
     misc_feature    510631..510945
                     /locus_tag="BCG_0438"
                     /note="Protein of unknown function (DUF3054); Region:
                     DUF3054; pfam11255"
                     /db_xref="CDD:256379"
     gene            complement(511170..512273)
                     /gene="mmpL1b"
                     /locus_tag="BCG_0439c"
                     /db_xref="GeneID:4697008"
     CDS             complement(511170..512273)
                     /gene="mmpL1b"
                     /locus_tag="BCG_0439c"
                     /note="In Mycobacterium tuberculosis strain H37Rv, mmpL1
                     exists as a single gene. In Mycobacterium bovis BCG
                     Pasteur, and Mycobacterium bovis, a frameshift due to a
                     single base deletion (c-*) splits mmpL1 into 2 parts,
                     mmpL1a and mmpL1b"
                     /codon_start=1
                     /transl_table=11
                     /product="transmembrane transport protein mmpL1b"
                     /protein_id="YP_976537.1"
                     /db_xref="GI:121636314"
                     /db_xref="GeneID:4697008"
                     /translation="MNSMDNVDKLTEDLANLTDDTERMDTTQRQLLAQLDPTIATMQT
                     VKDLAQTLTSAFSGLVTQMEDMTRNATVMGRTFDAANNDDSFYLPPEAFQNPDFQRGL
                     KLFLSPDGTCARFVITHRGDPASAEGISHIDPIMQAADEAVKGTPLQAASIYLAGTSS
                     TYKDIHEGTLYDVMIAVVASLCLIFIIMLGITRSVVASAVIVGTVALSLGSAFGLSVL
                     IWQHILHMPLHWLVLPMAIIVMLAVGSDYNLLLIARFQEEIGAGLKTGMIRAMAGTGR
                     VVTIAGLVFAFTMGSMVASDLRVVGQIGTTIMIGLLFDTLVVRSYMTPALATLLGRWF
                     WWPRRVDRLARQPQVLGPRRTTALSAERAALLQ"
     misc_feature    complement(511248..>512270)
                     /gene="mmpL1b"
                     /locus_tag="BCG_0439c"
                     /note="Predicted drug exporters of the RND superfamily
                     [General function prediction only]; Region: COG2409"
                     /db_xref="CDD:225272"
     misc_feature    complement(511233..512246)
                     /gene="mmpL1b"
                     /locus_tag="BCG_0439c"
                     /note="MMPL family; Region: MMPL; pfam03176"
                     /db_xref="CDD:251779"
     gene            complement(512270..514045)
                     /gene="mmpL1a"
                     /locus_tag="BCG_0440c"
                     /db_xref="GeneID:4695519"
     CDS             complement(512270..514045)
                     /gene="mmpL1a"
                     /locus_tag="BCG_0440c"
                     /note="In Mycobacterium tuberculosis strain H37Rv, mmpL1
                     exists as a single gene. In Mycobacterium bovis, a
                     frameshift due to a single base deletion (c-*) splits
                     mmpL1 into 2 parts, mmpL1a and mmpL1b;
                     Differs from Rv0402c by 1aa, P451L"
                     /codon_start=1
                     /transl_table=11
                     /product="transmembrane transport protein mmpL1a"
                     /protein_id="YP_976538.1"
                     /db_xref="GI:121636315"
                     /db_xref="GeneID:4695519"
                     /translation="MRSQRLAGHLSAAARTIHALSLPIILFWVALTIVVNVVAPQLQS
                     VARTHSVALGPHDAPSLIAMKRIGKDFQQFDSDTTAMVLLEGQEKLGDEAHRFYDVLV
                     TKLSQDTTHVQHIENFWGDPLTAAGSQSADGKAAYVQLNLTGDQGGSQANESVAAVQR
                     IVDSVPPPPGIKAYVTGPGPLGADRVVYGDRSLHTITGISIAVIAIMLFIAYRSLSAA
                     LIMLLTVGLELLAVRGIISTFAVNDLMGLSTFTVNVLVALTIAASTDYIIFLVGRYQE
                     ARATGQNREAAYYTMFGGTAHVVLASGLTVAGAMYCLGFTRLPYFNTLASPCAIGLVT
                     VMLASLTLAPAIIAVASRFGLFDPKRATTKRRWRRIGTVVVRWPGPVLAATLLIALIG
                     LLALPKYQTNYNERYYIPSAAPSNIGYLASDRHFPQARMEPEVLMVEADHDLRNPTDM
                     PILDRIAKTVFHTPGIARVQSITRPLGAPIDHSSIPFQLGMQSTMTIENLQNLKDRVA
                     DLSTLTDQLQRMIDITQRTQELTRQLTDATHDMNAHTRQMRDNANELRDRIADFDDFW
                     RPSEVSRTGSATASTFPSAGRCAPC"
     misc_feature    complement(<512342..514024)
                     /gene="mmpL1a"
                     /locus_tag="BCG_0440c"
                     /note="Predicted drug exporters of the RND superfamily
                     [General function prediction only]; Region: COG2409"
                     /db_xref="CDD:225272"
     misc_feature    complement(512903..513892)
                     /gene="mmpL1a"
                     /locus_tag="BCG_0440c"
                     /note="MMPL family; Region: MMPL; pfam03176"
                     /db_xref="CDD:251779"
     gene            complement(514042..514470)
                     /gene="mmpS1"
                     /locus_tag="BCG_0441c"
                     /db_xref="GeneID:4695518"
     CDS             complement(514042..514470)
                     /gene="mmpS1"
                     /locus_tag="BCG_0441c"
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein mmpS1"
                     /protein_id="YP_976539.1"
                     /db_xref="GI:121636316"
                     /db_xref="GeneID:4695518"
                     /translation="MFGVAKRFWIPMVIVIVVAVAAVTVSRLHSVFGSHQHAPDTGNL
                     DPIIAFYPKHVLYEVFGPPGTVASINYLDADAQPHEVVNAAVPWSFTIVTTLTAVVAN
                     VVARGDGASLGCRITVNEVIREERIVNAYHAHTSCLVKSA"
     misc_feature    complement(514045..514461)
                     /gene="mmpS1"
                     /locus_tag="BCG_0441c"
                     /note="Mycobacterium membrane protein; Region:
                     Mycobact_memb; pfam05423"
                     /db_xref="CDD:114164"
     gene            514791..516548
                     /gene="fadD30"
                     /locus_tag="BCG_0442"
                     /db_xref="GeneID:4697490"
     CDS             514791..516548
                     /gene="fadD30"
                     /locus_tag="BCG_0442"
                     /EC_number="2.3.1.86"
                     /note="activates fatty acids by binding to coenzyme A"
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-CoA synthetase"
                     /protein_id="YP_976540.1"
                     /db_xref="GI:121636317"
                     /db_xref="GeneID:4697490"
                     /translation="MSVISTLRDRATTTPSDEAFVFMDYDTKTGDQIDRMTWSQLYSR
                     VTAVSAYLISYGRHADRRRTAAISAPQGLDYVAGFLGALCAGWAPVPLPEPLGSLRDK
                     RTGLAVLDCAADVVLTTSQAETRVRATIATHGASVTTPVIALDTLDEPSGDNCDLDSQ
                     LSDWSSYLQYTSGSTANPRGVVLSMRNVTENVDQIIRNYFRHEGGAPRLPSSVVSWLP
                     LYHDMGLMVGLFIPLFVGCPVILTSPEAFIRKPARWMQLLAKHQAPFSAAPNFAFDLA
                     VAKTSEEDMAGLDLGHVNTIINGSEQVQPNTITKFLRRFRPYNLMPAAVKPSYGMAEA
                     VVYLATTKAGSPPTSTEFDADSLARGHAELSTFETERATRLIRYHSDDKEPLLRIVDP
                     DSNIELGPGRIGEIWIHGKNVSTGYHNADDALNRDKFQASIREASAGTPRSPWLRTGD
                     LGFIVGDEFYIVGRMKDLIIQDGVNHYPDDIETTVKEFTGGRVAAFSVSDDGVEHLVI
                     AAEVRTEHGPDKVTIMDFSTIKRLVVSALSKLHGLHVTDFLLVPPGALPKTTSGKISR
                     AACAKQYGANKLQRVATFP"
     misc_feature    514791..516545
                     /gene="fadD30"
                     /locus_tag="BCG_0442"
                     /note="acyl-CoA synthetase; Validated; Region: PRK05850"
                     /db_xref="CDD:235624"
     misc_feature    514815..516515
                     /gene="fadD30"
                     /locus_tag="BCG_0442"
                     /note="Fatty acyl-AMP ligase (FAAL); Region: FAAL;
                     cd05931"
                     /db_xref="CDD:213297"
     misc_feature    order(515292..515294,515301..515318,515322..515327)
                     /gene="fadD30"
                     /locus_tag="BCG_0442"
                     /note="acyl-activating enzyme (AAE) consensus motif; other
                     site"
                     /db_xref="CDD:213297"
     misc_feature    order(515373..515375,515451..515459,515679..515681,
                     515688..515699,515772..515786,515799..515801,
                     515922..515924,516138..516140,516171..516173,
                     516180..516182)
                     /gene="fadD30"
                     /locus_tag="BCG_0442"
                     /note="active site"
                     /db_xref="CDD:213297"
     gene            516545..517927
                     /gene="pks6a"
                     /locus_tag="BCG_0443"
                     /db_xref="GeneID:4699138"
     CDS             516545..517927
                     /gene="pks6a"
                     /locus_tag="BCG_0443"
                     /note="In Mycobacterium tuberculosis strain H37Rv, pks6
                     exists as a single gene. In Mycobacterium bovis BCG
                     Pasteur, and Mycobacterium bovis, a frameshift due to
                     single base insertion (*-g) splits pks6 into 2 parts,
                     pks6a and pks6b"
                     /codon_start=1
                     /transl_table=11
                     /product="membrane bound polyketide synthase pks6a"
                     /protein_id="YP_976541.1"
                     /db_xref="GI:121636318"
                     /db_xref="GeneID:4699138"
                     /translation="MTDGSVTADKLQKWFREYLSTHIECHPNEVSLDVPIRDLGLKSI
                     DVLAIPGDLGDRFGFCIPDLAVWDNPSANDLIDSLLNQRSADSLRESHGHADRNTQGR
                     GSINEPVAVIGVGCRFPGDIDGPERLWDFLTEKKCAITAYPDRGFTNAGTFAESGGFL
                     KDVAGFDNRFFDIPPDEALRMDPQQRLLLEVSWEALEHAGIIPESLRLSRTGVFVGVS
                     STDYVRLVSASAQQKSTIWDNTGGSSSIIANRISYFLDIQGPSIVIDTACSSSLVAVH
                     LACRSLSTWDCDIALVGGTNVLISPEPWGGFREAGILSQTGCCHAFDKSADGMVRGEG
                     CGVIVLQRLSDARLEGRRILAILTGSAVNQDGKSNGIMAPNPSAQIGVLENACKSARV
                     DPLEIGYVEAHGTGTSLGDRIEAHALGMVFGRKRPGSGPLMIGSIKPNIGHLEGAAGI
                     AGLIKAGVDG"
     misc_feature    516581..516775
                     /gene="pks6a"
                     /locus_tag="BCG_0443"
                     /note="Phosphopantetheine attachment site; Region:
                     PP-binding; pfam00550"
                     /db_xref="CDD:249951"
     misc_feature    516854..>517912
                     /gene="pks6a"
                     /locus_tag="BCG_0443"
                     /note="Polyketide synthase modules and related proteins
                     [Secondary metabolites biosynthesis, transport, and
                     catabolism]; Region: COG3321"
                     /db_xref="CDD:225858"
     misc_feature    516863..517912
                     /gene="pks6a"
                     /locus_tag="BCG_0443"
                     /note="polyketide synthases (PKSs) polymerize simple fatty
                     acids into a large variety of different products, called
                     polyketides, by successive decarboxylating Claisen
                     condensations. PKSs can be divided into 2 groups, modular
                     type I PKSs consisting of one or...; Region: PKS; cd00833"
                     /db_xref="CDD:238429"
     misc_feature    order(517346..517348,517751..517753,517871..517873)
                     /gene="pks6a"
                     /locus_tag="BCG_0443"
                     /note="active site"
                     /db_xref="CDD:238429"
     gene            517914..520754
                     /gene="pks6b"
                     /locus_tag="BCG_0444"
                     /db_xref="GeneID:4696577"
     CDS             517914..520754
                     /gene="pks6b"
                     /locus_tag="BCG_0444"
                     /note="In Mycobacterium tuberculosis strain H37Rv, pks6
                     exists as a single gene. In Mycobacterium bovis, a
                     frameshift due to single base insertion (*-g), splits pks6
                     into 2 parts, pks6a and pks6b;
                     Differs from Mb0413 by 1aa, M921V"
                     /codon_start=1
                     /transl_table=11
                     /product="membrane bound polyketide synthase pks6b"
                     /protein_id="YP_976542.1"
                     /db_xref="GI:121636319"
                     /db_xref="GeneID:4696577"
                     /translation="MLMVERGSLLPSGGFTEPNPAIPFTELGLRVVDELQEWPVVAGR
                     PRRAGVSSFGFGGTNAHVIVEEAGSVGADTVSGRADVGGSGGGVVAWVISGKTASALA
                     AQAGRLGRYVRARPALDVVDVGYSLVSTRSVFDHRAVVVGQTRDELLAGLAGVVAGRP
                     EAGVVCGVGKPAGKTAFVFAGQGSQWLGMGSELYAAYPVFAEALDAVVDELDRHLRYP
                     LRDVIWGHDQDLLNTTEFAQPALFAVEVALYRLLMSWGVRPGLVLGHSVGELAAAHVA
                     GALCLPDAAMLVAARGRLMQALPAGGAMFAVQAREDEVAPMLGHDVSIAAVNGPASVV
                     ISGAHDAVSAIADRLRGQGRRVHRLAVSHAFHSALMEPMIAEFTAVAAELSVGLPTIP
                     VISNVTGQLVADDFASADYWARHIRAVVRFGDSVRSAHCAGASRFIEVGPGGGLTSLI
                     EASLADAQIVSVPTLRKDRPEPVSVMTAAAQGFVSGMGLDWASVFSGYRPKRVELPTY
                     AFQHQKFWLAPAPSVSDPTAAGQIGASDGGAELLASSGFAARLAGRSADEQLAAAIEV
                     VCEHAAAVLGRDGAAGLDAGQAFADSGFNSLSAVELRNRLTAVTAVTLPATAIFDHPT
                     PTELAQYLITQIDGHGSSAAAAANPAERIDALTDLFLQACDAGRDADGWKMVALASNT
                     RERMSSPVRNNVSKNVALLADGISDVVVICIPTLTVLSDQREYRDIANAMTGRHSVYS
                     LTLPGFDSSDALPQNADMIVETVSNAIIDVVGGSCRFVLSGYSSGGVLAYALCSHLSV
                     KHQRNPLGVALIDTYLPSQIANPSMNEGFSPNDTGKGLSREVIRVARMLNRLTATRLT
                     AAATYAAIFQAWEPGRSMAPVLNIVAKDRIATVENLREERINRWRTAAAEAAYSVAEV
                     PGDHFGMMSTSSEAIATEIHDWISGLVRGPHP"
     misc_feature    <517917..519833
                     /gene="pks6b"
                     /locus_tag="BCG_0444"
                     /note="Polyketide synthase modules and related proteins
                     [Secondary metabolites biosynthesis, transport, and
                     catabolism]; Region: COG3321"
                     /db_xref="CDD:225858"
     misc_feature    <517917..518105
                     /gene="pks6b"
                     /locus_tag="BCG_0444"
                     /note="Condensing enzymes; Family of enzymes that catalyze
                     a (decarboxylating or non-decarboxylating) Claisen-like
                     condensation reaction. Members are share strong structural
                     similarity, and are involved in the synthesis and
                     degradation of fatty acids, and the...; Region:
                     cond_enzymes; cl09938"
                     /db_xref="CDD:263929"
     misc_feature    518445..519317
                     /gene="pks6b"
                     /locus_tag="BCG_0444"
                     /note="Acyl transferase domain in polyketide synthase
                     (PKS) enzymes; Region: PKS_AT; smart00827"
                     /db_xref="CDD:214838"
     misc_feature    519564..519821
                     /gene="pks6b"
                     /locus_tag="BCG_0444"
                     /note="Phosphopantetheine attachment site; Region: PKS_PP;
                     smart00823"
                     /db_xref="CDD:214834"
     misc_feature    520041..>520358
                     /gene="pks6b"
                     /locus_tag="BCG_0444"
                     /note="Alpha/beta hydrolase family; Region: Abhydrolase_6;
                     pfam12697"
                     /db_xref="CDD:257231"
     misc_feature    520044..520724
                     /gene="pks6b"
                     /locus_tag="BCG_0444"
                     /note="Thioesterase; Region: PKS_TE; smart00824"
                     /db_xref="CDD:214835"
     gene            complement(520702..521520)
                     /locus_tag="BCG_0445c"
                     /db_xref="GeneID:4696578"
     CDS             complement(520702..521520)
                     /locus_tag="BCG_0445c"
                     /codon_start=1
                     /transl_table=11
                     /product="beta-lactamase"
                     /protein_id="YP_976543.1"
                     /db_xref="GI:121636320"
                     /db_xref="GeneID:4696578"
                     /translation="MVATRGTRLAALALAPRLAGMAELVQITDKVHLARGHAVNWVLV
                     TDDTGVLLIDAGYPGDRAEVLASLNKLGYTPGDVRAIVLTHAHIDHLGSAIWFAREHS
                     TPVYCHAEEVGHAKREYRENASVFDVALRSWRPRVAVWGIHLLRRGGLTGDGIPTAQP
                     LTAEAAAGLPGQPMAIFTPGHTSGHCSYVVDGVLASGDALITGHPMLRHRGPQLLPAV
                     FSHSQQNSIRSLAALALLETNILAPGHGELWHGPIRKATDEALERAQKSNHVFR"
     misc_feature    complement(520786..521403)
                     /locus_tag="BCG_0445c"
                     /note="Metallo-beta-lactamase superfamily; Region:
                     Lactamase_B; smart00849"
                     /db_xref="CDD:214854"
     gene            521598..522608
                     /gene="fgd1"
                     /locus_tag="BCG_0446"
                     /db_xref="GeneID:4696963"
     CDS             521598..522608
                     /gene="fgd1"
                     /locus_tag="BCG_0446"
                     /EC_number="1.-.-.-"
                     /standard_name="fgd"
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-6-phosphate dehydrogenase"
                     /protein_id="YP_976544.1"
                     /db_xref="GI:121636321"
                     /db_xref="GeneID:4696963"
                     /translation="MAELKLGYKASAEQFAPRELVELAVAAEAHGMDSATVSDHFQPW
                     RHQGGHAPFSLSWMTAVGERTNRLLLGTSVLTPTFRYNPAVIAQAFATMGCLYPNRVF
                     LGVGTGEALNEIATGYEGAWPEFKERFARLRESVGLMRQLWSGDRVDFDGDYYRLKGA
                     SIYDVPDGGVPVYIAAGGPAVAKYAGRAGDGFICTSGKGEELYTEKLMPAVREGAAAA
                     DRSVDGIDKMIEIKISYDPDPELALNNTRFWAPLSLTAEQKHSIDDPIEMEKAADALP
                     IEQIAKRWIVASDPDEAVEKVGQYVTWGLNHLVFHAPGHDQRRFLELFQSDLAPRLRR
                     LG"
     misc_feature    521607..>522257
                     /gene="fgd1"
                     /locus_tag="BCG_0446"
                     /note="N5,N10-methylenetetrahydromethanopterin reductase
                     (Mer) catalyzes the reduction of
                     N5,N10-methylenetetrahydromethanopterin with reduced
                     coenzyme F420 to N5-methyltetrahydromethanopterin and
                     oxidized coenzyme F420; Region:
                     Tetrahydromethanopterin_reductase; cd01097"
                     /db_xref="CDD:238530"
     misc_feature    <521790..>521915
                     /gene="fgd1"
                     /locus_tag="BCG_0446"
                     /note="Flavin-utilizing monoxygenases; Region:
                     Flavin_utilizing_monoxygenases; cl19096"
                     /db_xref="CDD:271834"
     gene            522601..524673
                     /gene="pta"
                     /locus_tag="BCG_0447"
                     /db_xref="GeneID:4695793"
     CDS             522601..524673
                     /gene="pta"
                     /locus_tag="BCG_0447"
                     /EC_number="2.3.1.8"
                     /note="catalyzes the synthesis of acetylphosphate or
                     propionylphosphate from acetyl-CoA or propionyl-CoA and
                     inorganic phosphate; when using propionyl-CoA the enzyme
                     is functioning in the anaerobic pathway catabolizing
                     threonine to propionate"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate acetyltransferase"
                     /protein_id="YP_976545.1"
                     /db_xref="GI:121636322"
                     /db_xref="GeneID:4695793"
                     /translation="MADSSAIYLAAPESQTGKSTIALGLLHRLTAMVAKVGVFRPITR
                     LSAERDYILELLLAHTSAGLPYERCVGVTYQQLHADRDDAIAEIVDSYHAMADECDAV
                     VVVGSDYTDVTSPTELSVNARIAVNLGAPVLLTVRAKDRTPDQVASVVEVCLAELDTQ
                     RAHTAAVVANRCELSAIPAVTDALRRFTPPSYVVPEEPLLSAPTVAELTQAVNGAVVS
                     GDVALREREVMGVLAAGMTADHVLERLTDGMAVITPGDRSDVVLAVASAHAAEGFPSL
                     SCIVLNGGFQLHPAIAALVSGLRLRLPVIATALGTYDTASAAASARGLVTATSQRKID
                     TALELMDRHVDVAGLLAQLTIPIPTVTTPQMFTYRLLQQARSDLMRIVLPEGDDDRIL
                     KSAGRLLQRGIVDLTILGDEAKVRLRAAELGVDLDGATVIEPCASELHDQFADQYAQL
                     RKAKGITVEHAREIMNDATYFGTMLVHNCHADGMVSGAAHTTAHTVRPALEIIKTVPG
                     ISTVSSIFLMCLPDRVLAYGDCAIIPNPTVEQLADIAICSARTAAQFGIEPRVAMLSY
                     STGDSGKGADVDKVRAATELVRAREPQLPVEGPIQYDAAVEPSVAATKLRDSPVAGRA
                     TVLIFPDLNTGNNTYKAVQRSAGAIAIGPVLQGLRKPVNDLSRGALVDDIVNTVAITA
                     IQAQGVHE"
     misc_feature    522610..524658
                     /gene="pta"
                     /locus_tag="BCG_0447"
                     /note="phosphate acetyltransferase; Reviewed; Region:
                     PRK05632"
                     /db_xref="CDD:235537"
     misc_feature    523219..523563
                     /gene="pta"
                     /locus_tag="BCG_0447"
                     /note="DRTGG domain; Region: DRTGG; pfam07085"
                     /db_xref="CDD:254050"
     misc_feature    523705..524661
                     /gene="pta"
                     /locus_tag="BCG_0447"
                     /note="phosphotransacetylase; Reviewed; Region: eutD;
                     PRK09653"
                     /db_xref="CDD:236609"
     gene            524666..525823
                     /gene="ackA"
                     /locus_tag="BCG_0448"
                     /db_xref="GeneID:4697315"
     CDS             524666..525823
                     /gene="ackA"
                     /locus_tag="BCG_0448"
                     /EC_number="2.7.2.1"
                     /note="AckA utilizes acetate and can acetylate CheY which
                     increases signal strength during flagellar rotation;
                     utilizes magnesium and ATP; also involved in conversion of
                     acetate to aceyl-CoA"
                     /codon_start=1
                     /transl_table=11
                     /product="acetate kinase"
                     /protein_id="YP_976546.1"
                     /db_xref="GI:121636323"
                     /db_xref="GeneID:4697315"
                     /translation="MSSTVLVINSGSSSLKFQLVEPVAGMSRAAGIVERIGERSSPVA
                     DHAQALHRAFKMLAEDGIDLQTCGLVAVGHRVVHGGTEFHQPTLLDDTVIGKLEELSA
                     LAPLHNPPAVLGIKVARRLLANVAHVAVFDTAFFHDLPPAAATYAIDRDVADRWHIRR
                     YGFHGTSHQYVSERAAAFLGRPLDGLNQIVLHLGNGASASAIARGRPVETSMGLTPLE
                     GLVMGTRSGDLDPGVISYLWRTARMGVEDIESMLNHRSGMLGLAGERDFRRLRLVIET
                     GDRSAQLAYEVFIHRLRKYLGAYLAVLGHTDVVSFTAGIGENDAAVRRDALAGLQGLG
                     IALDQDRNLGPGHGARRISSDDSPIAVLVVPTNEELAIARDCLRVLGGRRA"
     misc_feature    524678..525814
                     /gene="ackA"
                     /locus_tag="BCG_0448"
                     /note="acetate kinase A/propionate kinase 2; Reviewed;
                     Region: PRK00180"
                     /db_xref="CDD:234680"
     gene            complement(525877..528129)
                     /gene="pknG"
                     /locus_tag="BCG_0449c"
                     /db_xref="GeneID:4698962"
     CDS             complement(525877..528129)
                     /gene="pknG"
                     /locus_tag="BCG_0449c"
                     /EC_number="2.7.1.-"
                     /codon_start=1
                     /transl_table=11
                     /product="Serine/threonine-protein kinase pknG"
                     /protein_id="YP_976547.1"
                     /db_xref="GI:121636324"
                     /db_xref="GeneID:4698962"
                     /translation="MAKASETERSGPGTQPADAQTATSATVRPLSTQAVFRPDFGDED
                     NFPHPTLGPDTEPQDRMATTSRVRPPVRRLGGGLVEIPRAPDIDPLEALMTNPVVPES
                     KRFCWNCGRPVGRSDSETKGASEGWCPYCGSPYSFLPQLNPGDIVAGQYEVKGCIAHG
                     GLGWIYLALDRNVNGRPVVLKGLVHSGDAEAQAMAMAERQFLAEVVHPSIVQIFNFVE
                     HTDRHGDPVGYIVMEYVGGQSLKRSKGQKLPVAEAIAYLLEILPALSYLHSIGLVYND
                     LKPENIMLTEEQLKLIDLGAVSRINSFGYLYGTPGFQAPEIVRTGPTVATDIYTVGRT
                     LAALTLDLPTRNGRYVDGLPEDDPVLKTYDSYGRLLRRAIDPDPRQRFTTAEEMSAQL
                     TGVLREVVAQDTGVPRPGLSTIFSPSRSTFGVDLLVAHTDVYLDGQVHAEKLTANEIV
                     TALSVPLVDPTDVAASVLQATVLSQPVQTLDSLRAARHGALDADGVDFSESVELPLME
                     VRALLDLGDVAKATRKLDDLAERVGWRWRLVWYRAVAELLTGDYDSATKHFTEVLDTF
                     PGELAPKLALAATAELAGNTDEHKFYQTVWSTNDGVISAAFGLARARSAEGDRVGAVR
                     TLDEVPPTSRHFTTARLTSAVTLLSGRSTSEVTEEQIRDAARRVEALPPTEPRVLQIR
                     ALVLGGALDWLKDNKASTNHILGFPFTSHGLRLGVEASLRSLARVAPTQRHRYTLVDM
                     ANKVRPTSTF"
     misc_feature    complement(526948..527682)
                     /gene="pknG"
                     /locus_tag="BCG_0449c"
                     /note="Catalytic domain of bacterial Serine/Threonine
                     kinases, PknB and similar proteins; Region:
                     STKc_PknB_like; cd14014"
                     /db_xref="CDD:270916"
     misc_feature    complement(order(527431..527433,527482..527493,
                     527506..527508,527521..527523,527602..527607,
                     527680..527682))
                     /gene="pknG"
                     /locus_tag="BCG_0449c"
                     /note="dimer interface [polypeptide binding]; other site"
                     /db_xref="CDD:270916"
     misc_feature    complement(526966..527679)
                     /gene="pknG"
                     /locus_tag="BCG_0449c"
                     /note="Serine/Threonine protein kinases, catalytic domain;
                     Region: S_TKc; smart00220"
                     /db_xref="CDD:214567"
     misc_feature    complement(order(527197..527208,527242..527244,
                     527251..527256,527281..527283,527287..527292,
                     527296..527298,527302..527304,527407..527409,
                     527413..527415,527425..527436,527497..527499,
                     527587..527589,527593..527595,527635..527637,
                     527641..527652,527656..527661))
                     /gene="pknG"
                     /locus_tag="BCG_0449c"
                     /note="active site"
                     /db_xref="CDD:270916"
     misc_feature    complement(order(527251..527256,527281..527283,
                     527287..527292,527296..527298,527413..527415,
                     527425..527436,527497..527499,527587..527589,
                     527593..527595,527635..527637,527641..527652,
                     527656..527661))
                     /gene="pknG"
                     /locus_tag="BCG_0449c"
                     /note="ATP binding site [chemical binding]; other site"
                     /db_xref="CDD:270916"
     misc_feature    complement(order(527197..527208,527242..527244,
                     527290..527292,527296..527298,527302..527304,
                     527407..527409,527413..527415,527647..527649))
                     /gene="pknG"
                     /locus_tag="BCG_0449c"
                     /note="polypeptide substrate binding site [polypeptide
                     binding]; other site"
                     /db_xref="CDD:270916"
     misc_feature    complement(order(527197..527220,527239..527256))
                     /gene="pknG"
                     /locus_tag="BCG_0449c"
                     /note="activation loop (A-loop); other site"
                     /db_xref="CDD:270916"
     misc_feature    complement(526426..526614)
                     /gene="pknG"
                     /locus_tag="BCG_0449c"
                     /note="Tetratricopeptide repeat; Region: TPR_16;
                     pfam13432"
                     /db_xref="CDD:257757"
     gene            complement(528129..529115)
                     /gene="glnH"
                     /locus_tag="BCG_0450c"
                     /db_xref="GeneID:4697522"
     CDS             complement(528129..529115)
                     /gene="glnH"
                     /locus_tag="BCG_0450c"
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine-binding lipoprotein glnH"
                     /protein_id="YP_976548.1"
                     /db_xref="GI:121636325"
                     /db_xref="GeneID:4697522"
                     /translation="MTRRALLARAAAPLAPLALAMVLASCGHSETLGVEATPTLPLPT
                     PVGMEIMPPQPPLPPDSSSQDCDPTASLRPFATKAEADAAVADIRARGRLIVGLDIGS
                     NLFSFRDPITGEITGFDVDIAGEVARDIFGVPSHVEYRILSAAERVTALQKSQVDIVV
                     KTMSITCERRKLVNFSTVYLDANQRILAPRDSPITKVSDLSGKRVCVARGTTSLRRIR
                     EIAPPPVIVSVVNWADCLVALQQREIDAVSTDDTILAGLVEEDPYLHIVGPDMADQPY
                     GVGINLD